Category ID Name Source p-value q-value Bonferroni q-value FDR B&H q-value FDR B&Y Hit Count in Query List Hit Count in Genome Hit in Query List GO: Molecular Function GO:0008092 cytoskeletal protein binding 7.68E-12 1.83E-08 1.83E-08 1.52E-07 188 886 "ACTN1,FMNL2,ADD1,ADD2,ADORA2A,BIN1,ANK2,MYH7B,APC,EPB41L5,GAS7,SHROOM2,SPTBN4,MARK4,ATP1A1,KIF1A,PROM1,DST,WASF1,CALM1,CAMK2B,CAPN3,HIP1R,SPAG9,PRC1,KRIT1,ARHGEF2,MAGI1,CFL2,CLTC,CNN3,PICK1,AKAP5,MYRIP,CRMP1,CLIP3,ARHGEF10,SIPA1L1,PHACTR3,KATNAL2,KIF26A,AIF1L,DBN1,JAKMIP2,KLHL3,KIF19,RAB39B,DMD,DYNC1I1,DPYSL2,KLHL5,EGFR,EPB41,EPB41L2,MTSS1L,GPHN,NCALD,APC2,KATNAL1,ADGRV1,CORO2B,DLC1,FER,FGF13,BAIAP2,EVL,FLNC,DCTN2,PDLIM5,STAU2,TPPP3,BRSK1,ABLIM2,FYN,IQGAP2,DISC1,TUBGCP4,PPARGC1A,STMN2,TPPP,PTPRT,GSN,FRMD5,PACSIN2,FRMD3,GABARAPL2,SYNPO,AGBL5,MYLK2,SCIN,KCNN2,KIF2A,KIF5A,KIFC3,KTN1,STMN1,PACRG,MAP2,MAP4,MAP6,MAPT,KCTD6,MID1,DBNL,BLOC1S2,MYH3,MYO5A,MYO6,MYO7A,MYO9A,NEFM,NEFH,NF1,NRCAM,OGG1,PDE4B,TMOD2,CCSER2,JAKMIP1,PLEC,FXYD1,EPB41L4B,PPP5C,BCAS3,PTK2,PTPRN,RAD51D,RDX,KIF7,KIRREL1,MAP6D1,LRRK2,CLIP1,AP1AR,S100B,KIF27,SGK1,KIF21A,KIF16B,MYO18A,FHOD3,SYBU,ABLIM3,PKNOX2,SLC8A1,SIRT2,CCDC88A,CDK5RAP2,MYH15,LIMCH1,SNAP25,SNCA,KIF13A,MYO16,SPTAN1,SPTB,CLASP2,ITPRID2,MPRIP,STX1A,SYNE2,SYN1,ARC,COBL,MTCL1,PDLIM2,AGTPBP1,KLHL4,TRIM2,CLASP1,SYNE1,OBSL1,TIAM1,TNS1,TPM1,TPM2,SYNPO2,NEIL2,RUSC1,PLEKHH2,WIPF1,CLIP2,KLC2,REEP1,DPYSL5,SPIRE1,ACTR3B,IFT88" GO: Molecular Function GO:0005085 guanyl-nucleotide exchange factor activity 1.73E-09 4.12E-06 1.53E-06 1.28E-05 79 306 "ABR,AMPH,FGD2,MADD,SPTBN4,DOCK11,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,ARHGEF25,ARHGEF1,ARHGEF2,RCBTB2,NGEF,ARHGEF6,NRG2,CSF2RA,ARHGEF10,RASGEF1C,ARHGEF4,DOCK4,GAPVD1,ELMO1,TIAM2,DOCK2,RASGRP1,EGFR,RASGRP2,ERBB2,ERBB4,DENND4A,FGF1,FGFR1,FGFR3,PSD2,FYN,DENND2A,RAPGEF6,GFRA2,GRIN2C,GRIN2D,KNDC1,JAK2,KIT,SHC3,KITLG,RASGEF1B,PSD,PTK2,IQSEC3,RASGRF1,RASGRF2,RET,RIC8B,SBF1,FNIP1,PREX2,ARHGEF40,FNBP1,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,MCF2L,DNMBP,DOCK9,TEK,TIAM1,TRIO,VAV1,P2RY12,DOCK8,SPATA13" GO: Molecular Function GO:0030695 GTPase regulator activity 1.93E-09 4.58E-06 1.53E-06 1.28E-05 80 312 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ARHGDIA,ARHGDIG,ARRB1,RGS20,ADGRB3,RGS11,RGS9,KALRN,KRIT1,ARHGEF1,DGKI,ARHGAP33,EVI5L,CHN1,CHN2,ARHGAP22,SLIT2,ARHGEF6,RGS6,SIPA1L1,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SGSM2,CPEB2,DOCK2,FAM13A,RASA4,TNK2,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,IQGAP2,RUNDC3A,ADAP1,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,IPO5,STXBP5,GIT1,MYO9A,NF1,TBC1D25,OCRL,GPSM2,PLXNB1,RAP1GDS1,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,RASA3,ASAP3,PREX2,ARFGAP1,ARHGAP26,PLCB1,ARHGAP9,TSC1,TSC2,TBC1D15,EVI5" GO: Molecular Function GO:0005088 Ras guanyl-nucleotide exchange factor activity 9.55E-09 2.27E-05 5.67E-06 4.74E-05 63 232 "ABR,FGD2,MADD,SPTBN4,DOCK11,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,ARHGEF25,ARHGEF1,ARHGEF2,RCBTB2,NGEF,ARHGEF6,NRG2,CSF2RA,ARHGEF10,ARHGEF4,TIAM2,DOCK2,RASGRP1,EGFR,ERBB2,ERBB4,DENND4A,FGF1,FGFR1,FGFR3,FYN,DENND2A,GFRA2,GRIN2C,GRIN2D,KNDC1,JAK2,KIT,SHC3,KITLG,RASGEF1B,PTK2,RASGRF1,RASGRF2,RET,SBF1,PREX2,ARHGEF40,SPTAN1,SPTB,MCF2L2,ST5,RGL1,ARHGEF9,MCF2L,DNMBP,DOCK9,TEK,TIAM1,TRIO,VAV1,SPATA13" GO: Molecular Function GO:0060589 nucleoside-triphosphatase regulator activity 2.01E-08 4.78E-05 9.56E-06 7.98E-05 83 344 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,ADGRB3,RGS11,RGS9,KALRN,KRIT1,ARHGEF1,DGKI,ARHGAP33,EVI5L,CHN1,CHN2,ARHGAP22,SLIT2,ARHGEF6,BAG4,RGS6,SIPA1L1,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SGSM2,CPEB2,DOCK2,DNAJB6,FAM13A,RASA4,TNK2,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,IQGAP2,RUNDC3A,ADAP1,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,IPO5,STXBP5,GIT1,MYO9A,NF1,TBC1D25,OCRL,GPSM2,PLXNB1,RAP1GDS1,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,RASA3,ASAP3,PREX2,ARFGAP1,ARHGAP26,PLCB1,ARHGAP9,TSC1,TSC2,TBC1D15,EVI5" GO: Molecular Function GO:0098772 molecular function regulator 3.39E-08 8.05E-05 1.34E-05 1.12E-04 258 1430 "RALGAPA1,ABR,ELFN2,AXIN2,ADRB2,AGT,TBC1D14,TAOK1,ARHGAP20,AMPH,OGT,DPP10,FGD2,PI16,APAF1,KCNAB2,APC,APOC1,APOC2,PPP4R4,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,CCAR2,DYNLL1,ATP1B3,DOCK11,ADGRB3,RGS11,RGS9,CFLAR,ARHGEF7,C5,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,CAPN3,CAST,ARHGEF25,KRIT1,CCNH,CCNT1,RGN,ARHGEF1,DGKI,ARHGEF2,KCNAB3,ARHGAP33,EVI5L,RCBTB2,SOCS6,CHN1,CHN2,ARHGAP22,SLIT2,NRXN3,PLAA,STOML1,NGEF,ARHGEF6,CABP1,BAG4,NRG2,NCOR1,RGS6,CSF2RA,ARHGEF10,SIPA1L1,SOCS5,PHACTR3,CST3,RASGEF1C,PPP1R16B,ARHGEF4,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ELMO1,B3GAT3,TIAM2,LYPD1,SPOCK3,SGSM2,DMPK,CPEB2,DOCK2,CASP8AP2,DPP6,RCAN1,DNAJB6,RASGRP1,FRY,FAM13A,EGFR,RASA4,TNK2,RGS17,PCOLCE2,RCAN2,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,TAOK3,DLC1,RACK1,STRADA,PPP1R1B,FGF1,FGF12,FGF13,FGFR1,FGFR3,PRKAG2,HPCAL4,VTI1B,AGAP2,AGAP3,PSD2,ATP6V1H,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,MALT1,RUNDC3A,DBF4,KCNMB4,ADAP1,GRIN2C,GRIN2D,GRM2,NCKAP1L,ARHGAP36,AGFG1,SMAP1,IGF1,KNDC1,INPP5B,LRRTM1,JAK2,KIT,IPO5,STXBP5,CAMK2N2,SHC3,MIA2,KITLG,MMP16,MMP17,GIT1,COL28A1,DBNL,MYO9A,NF1,NPY,TBC1D25,OCRL,PDPK1,SERPINI1,PIK3R1,GPSM2,FXYD1,PLXNB1,PPP1R1A,PPP2R2B,PPP2R2C,PPP2R5E,RASGEF1B,PKIA,PRKAR1B,PRKCB,MAPK9,PRPSAP2,PSD,BCAS3,PTK2,PTN,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS12,RIC8B,RNH1,FBXW7,SGSM1,LRRK2,KCNIP3,KCNIP1,SBF1,SCN2B,FNIP1,SEC14L1,RASA3,SGK1,ASAP3,PREX2,ARHGEF40,ARFGAP1,SNCA,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,SSPO,ST5,RGL1,STX1A,ARHGEF9,PLCB1,MCF2L,DNMBP,DOCK9,ARHGAP9,TEK,TIAM1,TIMP4,CABIN1,PIK3R5,TRIO,KCNE5,TSC1,TSC2,HSPBP1,SGK3,FLRT2,BCL2L13,VAV1,TBC1D15,P2RY12,WNT7A,RICTOR,ELFN1,CRB2,EVI5,KCNAB1,WNK3,DOCK8,SOCS4,SPATA13" GO: Molecular Function GO:0005509 calcium ion binding 7.22E-08 1.71E-04 2.45E-05 2.04E-04 143 708 "ACTN1,ESYT2,SLC24A4,PCDH19,SPARCL1,PCDH10,LTBP4,SYT13,DOC2A,PITPNM2,CADPS,PCDHGB4,ATP2A2,ATP2B2,DST,CACNA1B,CALB1,CALB2,CABP7,CALM1,CAPN3,RGN,CDH2,CLGN,SLIT2,EPS15L1,CPNE6,MYL6B,CABP1,CPS1,VCAN,PITPNM3,DGKB,DGKG,SPOCK2,AIF1L,SPOCK3,EDIL3,RASGRP1,CELSR3,RASGRP2,NCALD,ADGRV1,MEX3B,HPCAL4,SYT3,EFCAB2,CAMKK2,ATP2C1,CGREF1,DLL3,SYT17,PCDH17,HPGDS,GPD2,PCLO,PLCD4,ADAMTS13,GSN,PADI2,MAN1B1,NKD1,SCIN,C2CD4C,CDH20,SYTL4,MATN2,MATN3,EFHB,LRP1B,MMP16,MMP17,MYO5A,NELL2,VWA2,NUCB2,PCDHGC3,PCDH8,PCDH9,ENPP2,PLCB2,PLCD1,SLC25A23,PCDH18,NECAB2,PPP3CA,EPDR1,DCHS2,MASP1,FAT4,CRTAC1,RET,KCNIP3,KCNIP1,RYR3,S100B,SLC8A1,SNCA,SPTAN1,CLSTN2,SULF2,NECAB1,RHBDL3,PLCB1,SYT1,SYT5,ADGRL3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PHF24,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,VWCE,DNAH7,CDH22,VLDLR,VSNL1,PCDH20,MICU3,CRB2,FSTL5,PLSCR4" GO: Molecular Function GO:0005096 GTPase activator activity 9.08E-08 2.16E-04 2.70E-05 2.25E-04 70 283 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ARHGDIA,ARHGDIG,ARRB1,RGS20,ADGRB3,RGS11,RGS9,KALRN,ARHGEF1,ARHGAP33,EVI5L,CHN1,CHN2,ARHGAP22,ARHGEF6,RGS6,SIPA1L1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SGSM2,DOCK2,FAM13A,RASA4,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,IQGAP2,ADAP1,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,STXBP5,GIT1,MYO9A,NF1,TBC1D25,OCRL,PLXNB1,RAP1GDS1,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,RASA3,ASAP3,PREX2,ARFGAP1,ARHGAP26,PLCB1,ARHGAP9,TSC2,TBC1D15,EVI5" GO: Molecular Function GO:0015631 tubulin binding 1.74E-07 4.14E-04 4.60E-05 3.84E-04 71 293 "APC,MARK4,KIF1A,DST,PRC1,KRIT1,ARHGEF2,CNN3,CLIP3,KATNAL2,KIF26A,JAKMIP2,KIF19,DYNC1I1,DPYSL2,NCALD,APC2,KATNAL1,FGF13,TPPP3,BRSK1,FYN,TUBGCP4,PPARGC1A,STMN2,TPPP,GABARAPL2,AGBL5,KIF2A,KIF5A,KIFC3,STMN1,PACRG,MAP2,MAP4,MAP6,MAPT,MID1,BLOC1S2,NEFM,NEFH,NF1,OGG1,PDE4B,CCSER2,JAKMIP1,PPP5C,BCAS3,RAD51D,KIF7,MAP6D1,LRRK2,CLIP1,KIF27,KIF21A,KIF16B,SYBU,SIRT2,CCDC88A,CDK5RAP2,SNCA,KIF13A,CLASP2,MTCL1,AGTPBP1,CLASP1,TIAM1,NEIL2,CLIP2,REEP1,DPYSL5" GO: Molecular Function GO:0008017 microtubule binding 2.41E-07 5.72E-04 5.72E-05 4.77E-04 56 214 "APC,MARK4,KIF1A,DST,PRC1,KRIT1,ARHGEF2,CNN3,CLIP3,KATNAL2,KIF26A,JAKMIP2,KIF19,DYNC1I1,DPYSL2,APC2,KATNAL1,FGF13,TUBGCP4,TPPP,GABARAPL2,KIF2A,KIF5A,KIFC3,MAP2,MAP4,MAP6,MAPT,MID1,NEFM,NEFH,NF1,OGG1,CCSER2,JAKMIP1,PPP5C,KIF7,MAP6D1,LRRK2,CLIP1,KIF27,KIF21A,KIF16B,SYBU,CCDC88A,CDK5RAP2,SNCA,KIF13A,CLASP2,MTCL1,CLASP1,TIAM1,NEIL2,CLIP2,REEP1,DPYSL5" GO: Molecular Function GO:0017075 syntaxin-1 binding 1.20E-06 2.86E-03 2.60E-04 2.17E-03 12 20 "SNPH,DAPK1,CPLX2,CPLX1,STXBP5,MYO5A,LRRK2,SYBU,SNAP25,STXBP1,SYP,SYT1" GO: Molecular Function GO:0005089 Rho guanyl-nucleotide exchange factor activity 1.93E-06 4.59E-03 3.83E-04 3.20E-03 27 80 "ABR,FGD2,DOCK11,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,DOCK2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,DOCK9,TIAM1,TRIO,VAV1,SPATA13" GO: Molecular Function GO:0032559 adenyl ribonucleotide binding 2.60E-06 6.18E-03 4.75E-04 3.97E-03 260 1518 "ABCF1,SYN3,CLK4,ADCY5,ADCY6,ADCY8,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,CDK10,CASK,CDK13,STK33,DNAH17,MARK4,ATP1A1,ATP1A3,ATP2A2,ATP2B2,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,CARS,P2RX6,ENTPD2,DGKI,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,ABCG2,MAP4K4,AKAP7,SMARCAL1,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,KIF19,DMPK,DNAH9,RPS6KL1,FARSB,ABCC5,AASDH,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,CHST15,STRADA,FER,FGFR1,FGFR3,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,IP6K3,ACSS1,GCK,SRCAP,TTBK1,GLUL,DCLK2,CIT,BVES,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,MYLK2,NIM1K,ITPKA,ITPKB,JAK2,KHK,KIF2A,KIF5A,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,NRBP2,MYH3,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,KSR2,P2RX7,P2RY1,CDK18,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,ABCB1,PIK3C2A,PKM,PPP5C,PRKACB,PRKAR1B,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,CNNM2,SNRK,PTK2,STK32A,ACSM5,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,KIF7,RNASEL,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,SMARCA4,MAST1,MYH15,KIF13A,MYO16,NMNAT2,CDK19,ATP10B,NEK4,TTBK2,SYN1,SYN2,SIK3,TEK,DNAH7,DICER1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,MAP3K12,GAL3ST3,NAV3,ITM2C,WNK3,WNK2,DNAH10,ACTR3B,NLRP3" GO: Molecular Function GO:0030554 adenyl nucleotide binding 3.42E-06 8.13E-03 5.54E-04 4.63E-03 261 1530 "ABCF1,SYN3,CLK4,ADCY5,ADCY6,ADCY8,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,CDK10,CASK,CDK13,STK33,DNAH17,MARK4,ATP1A1,ATP1A3,ATP2A2,ATP2B2,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,CARS,P2RX6,ENTPD2,DGKI,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,ABCG2,MAP4K4,AKAP7,SMARCAL1,BAG4,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,KIF19,DMPK,DNAH9,RPS6KL1,FARSB,ABCC5,AASDH,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,CHST15,STRADA,FER,FGFR1,FGFR3,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,IP6K3,ACSS1,GCK,SRCAP,TTBK1,GLUL,DCLK2,CIT,BVES,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,MYLK2,NIM1K,ITPKA,ITPKB,JAK2,KHK,KIF2A,KIF5A,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,NRBP2,MYH3,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,KSR2,P2RX7,P2RY1,CDK18,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,ABCB1,PIK3C2A,PKM,PPP5C,PRKACB,PRKAR1B,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,CNNM2,SNRK,PTK2,STK32A,ACSM5,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,KIF7,RNASEL,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,SMARCA4,MAST1,MYH15,KIF13A,MYO16,NMNAT2,CDK19,ATP10B,NEK4,TTBK2,SYN1,SYN2,SIK3,TEK,DNAH7,DICER1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,MAP3K12,GAL3ST3,NAV3,ITM2C,WNK3,WNK2,DNAH10,ACTR3B,NLRP3" GO: Molecular Function GO:0016773 "phosphotransferase activity, alcohol group as acceptor" 3.50E-06 8.32E-03 5.54E-04 4.63E-03 147 781 "KCNH8,CLK4,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,NRP2,KSR1,BMPR1B,BTK,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,CCNH,CCNT1,CD86,DGKI,DCLK1,TBRG4,TAOK2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,RASSF2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DMPK,RPS6KL1,EDNRA,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGF1,FGFR1,FGFR3,PRKAG2,IP6K2,FLT1,CAMKK2,BRSK1,FYN,IP6K3,GCK,TTBK1,DBF4,DCLK2,CNTRL,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,ITPKA,ITPKB,JAK2,KCNH2,KHK,KIT,MARK1,MARK3,MATK,KITLG,NRBP2,IDNK,NEK1,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PFKFB2,PFKFB3,PFKFB4,PIK3C2A,PIK3R1,PKM,PRKAB2,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RELN,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,HKDC1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,PIK3R5,CDK20,TRIO,SGK3,VAV1,SPHK2,MAP3K12,WNK3,WNK2" GO: Molecular Function GO:0016301 kinase activity 3.93E-06 9.34E-03 5.84E-04 4.88E-03 158 853 "KCNH8,CLK4,NME5,AK2,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,UPRT,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,NRP2,KSR1,BMPR1B,BTK,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,CCNH,CCNT1,CD86,DGKI,DCLK1,TBRG4,TAOK2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,RASSF2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DMPK,RPS6KL1,EDNRA,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGF1,FGFR1,FGFR3,PRKAG2,IP6K2,FLT1,AK8,TPK1,CAMKK2,MPP6,BRSK1,FYN,IP6K3,GCK,TTBK1,DBF4,DCLK2,CNTRL,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,NME9,ITPKA,ITPKB,JAK2,KCNH2,KHK,KIT,MARK1,MARK3,MATK,KITLG,MPP2,NRBP2,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PFKFB2,PFKFB3,PFKFB4,PIK3C2A,PIK3R1,PKM,PRKAB2,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RELN,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,HKDC1,SEPHS1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,TK2,PIK3R5,CDK20,TRIO,SGK3,VAV1,SPHK2,MAP3K12,WNK3,WNK2" GO: Molecular Function GO:0005516 calmodulin binding 4.90E-06 1.16E-02 6.84E-04 5.72E-03 48 190 "ADCY8,ADD1,ADD2,CASK,ATP2B2,CACNA1A,CAMK2A,CAMK2B,CAMK2G,USP6,CNN3,AKAP5,CTH,DAPK1,EGFR,EPB41,CAMKK2,IQGAP2,MYLK2,ITPKA,ITPKB,KCNN1,KCNN2,KCNN3,KCNQ3,MAP2,MAP6,MYH3,MYO5A,MYO6,MYO7A,PDE1C,PDE1B,PIK3R1,STRN3,PPP3CA,PPP3CC,CEP97,RASGRF2,RGS4,MAP6D1,RYR3,SLC8A1,CDK5RAP2,MYH15,SPTAN1,PLCB1,SYT1" GO: Molecular Function GO:0004672 protein kinase activity 9.75E-06 2.32E-02 1.29E-03 1.07E-02 124 649 "KCNH8,CLK4,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,NRP2,KSR1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,CCNH,CCNT1,DCLK1,TBRG4,TAOK2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,RASSF2,DAPK1,DAPK3,DMPK,RPS6KL1,EDNRA,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGF1,FGFR1,FGFR3,PRKAG2,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DBF4,DCLK2,CNTRL,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,ITPKA,JAK2,KCNH2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PRKAB2,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RELN,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,MAP3K12,WNK3,WNK2" GO: Molecular Function GO:0008022 protein C-terminus binding 1.26E-05 2.99E-02 1.46E-03 1.22E-02 53 224 "ADCY8,AP2A1,AMPH,CASK,DYNLL1,ATP2A2,ATP2B2,MPDZ,KSR1,DST,SYNJ1,BAIAP3,CACNA1B,MAGI1,FOXN3,PLEKHB1,CLTC,CNGA3,HOMER3,PICK1,AKAP7,DAPK3,DNM1,MED12,SHANK1,OPTN,ERBB2,ERCC2,BAIAP2,HPCAL4,SDCBP2,MCHR1,JAK2,KCNK3,LIG4,AFDN,DBNL,BLOC1S2,NCF2,OPRL1,PIK3R1,RASGRF1,FIGN,KCNIP3,ATXN2,PEX26,PRRC2C,SYT1,TBL1X,TCF4,SIRT1,ITGB3BP,XRCC4" GO: Molecular Function GO:0019904 protein domain specific binding 1.29E-05 3.05E-02 1.46E-03 1.22E-02 136 729 "ACTN1,AXIN2,CASKIN1,OGT,EPB41L5,SHROOM2,CASK,RGS20,ARRB2,DYNLL1,ATP1A1,ATP2B2,RIPK1,ADAM15,HCN2,SYNJ1,SYNJ2,CALM1,HAP1,LDB2,SYNGR3,DLGAP2,DLGAP1,ASIC3,CLCN3,QKI,HOMER3,PICK1,AKAP7,WHRN,AKAP5,ZNF521,NCOR1,RGS6,IPCEF1,ERC2,ARHGEF4,RIMS2,DOCK4,IST1,DAPK3,ELMO1,MED12,SHANK1,PDCD6IP,DTNA,EBF1,HEYL,PLEKHA1,TNK2,EPB41L2,DLC1,RACK1,BAIAP2,HPCAL4,EVL,STAMBP,TRIM16,KHDRBS3,MPP6,IGSF5,ARFIP1,GHR,LNX1,GRIA2,GRIK5,GRIN2C,CIT,GSN,TCEAL6,ICA1,NKD1,JAK2,KCNH2,KCNN2,L1CAM,LAMP2,MAPT,MEF2C,SRSF12,AFDN,MPP2,DBNL,MYO7A,TCEAL5,HNRNPM,NFE2L2,PAX6,PIK3R1,PKD1,STRN3,SH3KBP1,PPARA,CNTLN,PTK2,USP47,KHDRBS2,RDX,ROBO1,RXRA,STX1B,ATXN2,SCAF8,SH3BGR,SH3BP2,SHC4,NLGN1,ELMO2,SLC22A4,CXXC4,SNAP25,SNCA,ERC1,NFASC,SSTR2,CEP68,STX1A,STXBP1,SYP,TACC1,TAF9,TBL1X,TCF12,DICER1,SIRT1,ZNF106,THRA,CABIN1,TP53BP2,LAT2,XPO1,TCEAL7,ZXDA,TUBA1A,PLSCR4,FZD3" GO: Molecular Function GO:0008047 enzyme activator activity 1.29E-05 3.06E-02 1.46E-03 1.22E-02 102 515 "RALGAPA1,ABR,AXIN2,AGT,TBC1D14,TAOK1,ARHGAP20,OGT,APAF1,APOC1,APOC2,MADD,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,ADGRB3,RGS11,RGS9,CFLAR,CALM1,KALRN,ARHGEF1,ARHGAP33,EVI5L,CHN1,CHN2,ARHGAP22,PLAA,ARHGEF6,RGS6,SIPA1L1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,B3GAT3,TIAM2,SGSM2,DOCK2,CASP8AP2,DNAJB6,FAM13A,RASA4,RGS17,PCOLCE2,TBC1D16,DLC1,RACK1,STRADA,FGF13,PRKAG2,AGAP2,AGAP3,IQGAP2,MALT1,RUNDC3A,DBF4,ADAP1,NCKAP1L,ARHGAP36,AGFG1,SMAP1,IGF1,INPP5B,STXBP5,MIA2,MMP16,MMP17,GIT1,DBNL,MYO9A,NF1,TBC1D25,OCRL,PDPK1,PLXNB1,MAPK9,BCAS3,RAP1GDS1,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,RASA3,ASAP3,PREX2,ARFGAP1,ARHGAP26,PLCB1,ARHGAP9,TSC2,BCL2L13,TBC1D15,RICTOR,EVI5" GO: Molecular Function GO:0044877 protein-containing complex binding 1.38E-05 3.27E-02 1.49E-03 1.24E-02 271 1626 "ABCF1,ACHE,ACTN1,ADD1,ADD2,ADORA1,ADRB2,BEND6,MTA3,AP2A1,AP2A2,C1QTNF1,LTBP4,AMPH,BIN1,SEMA7A,EP400,PHF12,PARG,APC,GAS7,SHROOM2,CASK,ARRB1,ARRB2,MARK4,NCOA1,CCAR2,RIPK1,KIF1A,ADAM23,ADAM15,RGS9,HCN2,CFLAR,DST,SYNJ1,WASF1,DDR1,PRC1,KRIT1,CCNT1,SCARB1,ARHGEF2,CDH2,DLGAP1,LRWD1,NOG,LHX2,VAX2,CNN3,PICK1,LETMD1,AKAP5,ABI3BP,CPS1,CLOCK,HINFP,NCOR1,NCOR2,CLIP3,SIPA1L1,ERC2,KATNAL2,HDAC4,KIF26A,TBC1D5,IST1,AIF1L,GIT2,DBN1,JAKMIP2,SACS,KIF19,DLX1,DNM1,USP3,MED12,DYNC1I1,SHANK1,CPEB2,DOCK2,DPYSL2,ECM2,EDIL3,EGFR,PCOLCE2,COQ7,EPHB1,APC2,KATNAL1,EZH1,PTK2B,CORO2B,FCGR1A,FCGR1B,FCGR3A,FCGRT,PRMT5,FGF1,FGF13,FGFR1,FOXO3,FLNC,STAU2,FYB1,FYN,GABRB3,IQGAP2,DISC1,ALDH1L1,TUBGCP4,PPARGC1A,GLI2,TOX3,CBX1,GNAL,GNAO1,GPER1,TPPP,GRB10,ADAMTS13,PSIP1,MUM1,NCKAP1L,GABARAPL2,MSL1,IGF1,RBPJ,SCIN,INSM1,ITGA7,KIF2A,KIF5A,KIFC3,L1CAM,LMO2,MAP2,MAP4,MAP6,MAPT,MBD1,ADAM11,MEF2C,MEIS1,MID1,MITF,GIT1,DBNL,ADAM22,MSR1,MYH3,MYO6,MYO7A,NEFM,NEFH,NF1,NME4,OGG1,PAX6,PDPK1,OLA1,PIK3R1,CCSER2,PKM,PLCB2,JAKMIP1,MTRF1L,PRIMPOL,STRN3,POLG,PPARA,PPP2R2B,LRRN3,PPP5C,PRKCB,BCAS3,APTX,PTCH1,PTK2,SPDL1,KIF7,PBRM1,RNASEL,ELP2,MCMBP,MAP6D1,LRRK2,CLIP1,RXRA,AP1AR,SAFB,SALL1,SATB1,ATXN7,KIF27,KIF21A,ARX,KIF16B,CPEB3,MYO18A,SHMT2,SYBU,PEX26,DHX30,PKNOX2,KDM4D,SIRT2,CDK5RAP3,CCDC88A,CPEB4,ZKSCAN3,SMARCA4,SMARCC2,CDK5RAP2,SMARCD3,SNCA,MBD5,KIF13A,LMBRD1,MYO16,DOK5,SOX15,KDM4C,SPTAN1,SPTB,CLASP2,CAMTA2,ITPRID2,ERBIN,SUPT5H,SYNE2,SYP,MTCL1,TAL1,TBL1X,SMG6,TCF4,SIN3B,SATB2,ZEB1,CLASP1,SYNE1,NSD1,SIRT1,THRA,TIAM1,RELL2,CBX5,ICAM5,KAT6B,CABIN1,PIK3R5,WBP2,DOK6,NEIL2,TRPS1,TSN,VLDLR,WIPF1,CLIP2,WRN,RICTOR,ZIC2,REEP1,DPYSL5,MEIS3,PRDM8,NELFE,RTN4,KAT6A" GO: Molecular Function GO:0005524 ATP binding 1.77E-05 4.20E-02 1.83E-03 1.53E-02 248 1475 "ABCF1,SYN3,CLK4,ADCY5,ADCY6,ADCY8,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,CDK10,CASK,CDK13,STK33,DNAH17,MARK4,ATP1A1,ATP1A3,ATP2A2,ATP2B2,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,CARS,P2RX6,ENTPD2,DGKI,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,ABCG2,MAP4K4,SMARCAL1,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,KIF19,DMPK,DNAH9,RPS6KL1,FARSB,ABCC5,AASDH,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,STRADA,FER,FGFR1,FGFR3,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,IP6K3,ACSS1,GCK,SRCAP,TTBK1,GLUL,DCLK2,CIT,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,MYLK2,NIM1K,ITPKA,ITPKB,JAK2,KHK,KIF2A,KIF5A,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,NRBP2,MYH3,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,KSR2,P2RX7,P2RY1,CDK18,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,ABCB1,PIK3C2A,PKM,PPP5C,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,CNNM2,SNRK,PTK2,STK32A,ACSM5,ACSS3,RAD17,RAD51D,NWD1,RET,FIGN,KIF7,RNASEL,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,SMARCA4,MAST1,MYH15,KIF13A,MYO16,NMNAT2,CDK19,ATP10B,NEK4,TTBK2,SYN1,SYN2,SIK3,TEK,DNAH7,DICER1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,MAP3K12,NAV3,ITM2C,WNK3,WNK2,DNAH10,ACTR3B,NLRP3" GO: Biological Process GO:0098916 anterograde trans-synaptic signaling 6.82E-25 6.03E-21 2.01E-21 1.94E-20 189 678 "SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,LRFN2,ADRB2,AGT,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,APBA2,PPFIA3,CASK,ARRB2,CADPS,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CBLN1,CD38,DGKI,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CPNE6,NRXN3,CLCN3,CNR1,PICK1,AKAP5,CRHBP,SNCAIP,SIPA1L1,RIMS4,SLITRK5,RIMS2,SNPH,DAPK1,DBI,DBN1,LYPD1,SNAP91,SV2B,DNM1,DMPK,SHANK1,SLC12A6,DTNA,EDN1,EDN3,EGFR,EGR3,STX2,ERBB4,PTK2B,FGF12,FGF14,BAIAP2,SYT3,CSPG5,STAU2,BRSK1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,CPLX2,CPLX1,PCDH17,PPARGC1A,GLUL,KCNMB4,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SHISA6,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNB1,KCND2,KCNK3,KCNN1,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,MAPT,MBP,SHC3,MEF2C,MYO5A,MYO6,NF1,NPY,NOVA1,NPTX1,NPTX2,NTRK2,OPRL1,OXTR,P2RX7,PCDH8,TMOD2,NLGN3,PLCL1,PMP22,PPP3CA,RELN,PTK2,PTN,PTPRD,PTPRN2,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,LRFN5,SCN2B,CPEB3,NLGN1,SLC6A11,SLC12A4,NAPB,SNAP25,SNCA,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,TACR1,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,RASD2,VGF,WNT7A,TRIM9,CELF4,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0007268 chemical synaptic transmission 6.82E-25 6.03E-21 2.01E-21 1.94E-20 189 678 "SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,LRFN2,ADRB2,AGT,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,APBA2,PPFIA3,CASK,ARRB2,CADPS,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CBLN1,CD38,DGKI,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CPNE6,NRXN3,CLCN3,CNR1,PICK1,AKAP5,CRHBP,SNCAIP,SIPA1L1,RIMS4,SLITRK5,RIMS2,SNPH,DAPK1,DBI,DBN1,LYPD1,SNAP91,SV2B,DNM1,DMPK,SHANK1,SLC12A6,DTNA,EDN1,EDN3,EGFR,EGR3,STX2,ERBB4,PTK2B,FGF12,FGF14,BAIAP2,SYT3,CSPG5,STAU2,BRSK1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,CPLX2,CPLX1,PCDH17,PPARGC1A,GLUL,KCNMB4,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SHISA6,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNB1,KCND2,KCNK3,KCNN1,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,MAPT,MBP,SHC3,MEF2C,MYO5A,MYO6,NF1,NPY,NOVA1,NPTX1,NPTX2,NTRK2,OPRL1,OXTR,P2RX7,PCDH8,TMOD2,NLGN3,PLCL1,PMP22,PPP3CA,RELN,PTK2,PTN,PTPRD,PTPRN2,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,LRFN5,SCN2B,CPEB3,NLGN1,SLC6A11,SLC12A4,NAPB,SNAP25,SNCA,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,TACR1,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,RASD2,VGF,WNT7A,TRIM9,CELF4,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0099537 trans-synaptic signaling 6.82E-25 6.03E-21 2.01E-21 1.94E-20 189 678 "SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,LRFN2,ADRB2,AGT,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,APBA2,PPFIA3,CASK,ARRB2,CADPS,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CBLN1,CD38,DGKI,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CPNE6,NRXN3,CLCN3,CNR1,PICK1,AKAP5,CRHBP,SNCAIP,SIPA1L1,RIMS4,SLITRK5,RIMS2,SNPH,DAPK1,DBI,DBN1,LYPD1,SNAP91,SV2B,DNM1,DMPK,SHANK1,SLC12A6,DTNA,EDN1,EDN3,EGFR,EGR3,STX2,ERBB4,PTK2B,FGF12,FGF14,BAIAP2,SYT3,CSPG5,STAU2,BRSK1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,CPLX2,CPLX1,PCDH17,PPARGC1A,GLUL,KCNMB4,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SHISA6,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNB1,KCND2,KCNK3,KCNN1,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,MAPT,MBP,SHC3,MEF2C,MYO5A,MYO6,NF1,NPY,NOVA1,NPTX1,NPTX2,NTRK2,OPRL1,OXTR,P2RX7,PCDH8,TMOD2,NLGN3,PLCL1,PMP22,PPP3CA,RELN,PTK2,PTN,PTPRD,PTPRN2,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,LRFN5,SCN2B,CPEB3,NLGN1,SLC6A11,SLC12A4,NAPB,SNAP25,SNCA,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,TACR1,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,RASD2,VGF,WNT7A,TRIM9,CELF4,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0099536 synaptic signaling 1.43E-24 1.26E-20 3.15E-21 3.04E-20 190 687 "SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,LRFN2,ADRB2,AGT,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,APBA2,PPFIA3,CASK,ARRB2,CADPS,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CBLN1,CD38,DGKI,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CPNE6,NRXN3,CLCN3,CNR1,PICK1,AKAP5,CRHBP,SNCAIP,SIPA1L1,RIMS4,SLITRK5,RIMS2,SNPH,DAPK1,DBI,DBN1,LYPD1,SNAP91,SV2B,DNM1,DMPK,SHANK1,SLC12A6,DTNA,EDN1,EDN3,EGFR,EGR3,STX2,ERBB4,PTK2B,FGF12,FGF14,BAIAP2,SYT3,CSPG5,STAU2,BRSK1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,CPLX2,CPLX1,PCDH17,PPARGC1A,GLUL,KCNMB4,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SHISA6,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNB1,KCND2,KCNK3,KCNN1,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,MAPT,MBP,SHC3,MEF2C,MYO5A,MYO6,NF1,NPY,NOVA1,NPTX1,NPTX2,NTRK2,OPRL1,OXTR,P2RX7,PCDH8,TMOD2,NLGN3,PLCL1,PMP22,PPP3CA,RELN,PTK2,PTN,PTPRD,PTPRN2,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,LRFN5,SCN2B,CPEB3,NLGN1,SLC6A11,SLC12A4,NAPB,SNAP25,SNCA,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,STXBP1,PLCB1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,TACR1,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,RASD2,VGF,WNT7A,TRIM9,CELF4,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0032990 cell part morphogenesis 2.17E-22 1.91E-18 3.83E-19 3.70E-18 229 925 "ACHE,ADORA2A,UNC5A,LRFN2,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NUMB,DYNLL1,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,ARHGEF7,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,EVI5L,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,CCDC151,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,RIMS2,USP6NL,BOC,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,PLPPR4,SNAP91,DMD,NYAP1,SHANK1,DPYSL2,ECM2,DNM1L,FIS1,WDPCP,SEMA3D,CELSR3,EGFR,PLXNC1,EIF4G2,COQ7,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,TUBB3,ZMYND10,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,TMEM107,PDLIM5,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,SEPT9,NTNG2,GLI2,CIT,GSN,RNF165,RABL2A,LINGO1,PACSIN2,KNDC1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,POC1B,DBNL,NBL1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,PAX6,ENPP2,NLGN3,SEMA5B,SNX10,PLXNB1,PPP3CA,CEP41,MAPK3,HYDIN,RELN,PTK2,PTPRD,PTPRO,TMEM231,PID1,CEP97,CCDC40,RET,RFX2,RFX3,KCTD17,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,ATXN2,LRFN5,KIF27,SGK1,ARX,FUZ,NLGN1,DZIP1,NUBPL,ABLIM3,PREX2,BTBD3,IFT122,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,TROVE2,TTBK2,KANK1,STXBP1,SYT1,COBL,ATMIN,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,DNAH7,DICER1,TIAM1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,TBC1D15,WNT7A,CFAP298,ZIC2,TMEM237,DPYSL5,MFF,EVI5,PRDM8,SEMA3B,FZD3,RTN4,IFT88" GO: Biological Process GO:0030030 cell projection organization 9.97E-22 8.80E-18 1.45E-18 1.41E-17 314 1423 "ACHE,ADCY6,ADORA2A,UNC5A,LRFN2,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,SEMA7A,FGD2,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,MARK4,NUMB,DYNLL1,ATP2B2,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,ARHGEF7,MTMR2,RAB29,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,CBFA2T2,SEPT7,CDH2,DCLK1,EVI5L,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CCDC151,ARHGEF6,CNR1,PICK1,CNTN1,WHRN,AKAP5,RTTN,BAG4,SH2B1,CRMP1,AATK,CSF1R,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,PPP1R16B,ARHGEF4,RIMS2,USP6NL,BOC,ARHGAP24,HDAC4,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,KIAA0319,PLPPR4,SNAP91,GRIN3A,DMD,NYAP1,DNAH9,SHANK1,DPYSL2,ECM2,E2F5,WDPCP,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G2,TENM1,PLEKHA1,MTSS1L,EPHB1,STX2,ERBB2,CDKL3,ETV1,ADGRV1,NRN1,SH3YL1,TBC1D16,ACSL4,PTK2B,TUBB3,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,TMEM107,PDLIM5,USP21,STAU2,BRSK1,FYN,CHL1,RAPGEF6,SYT17,DISC1,SEPT9,INPP5K,NTNG2,GLI2,GNAO1,STMN2,CIT,GSN,RNF165,RABL2A,LINGO1,PACSIN2,CFAP126,NEGR1,RBPJ,KNDC1,ITPKA,JAK2,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,GIT1,DBNL,BLOC1S2,MYO6,MYO7A,NBL1,NEFM,NEFH,CCDC13,NEK1,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,OPA1,P2RX7,PALM,PAX6,ENPP2,NLGN3,SEMA5B,SNX10,PLXNB1,PMP22,PPP3CA,CEP41,MAPK3,MAPK9,HYDIN,RELN,KLK6,BCAS3,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,STRC,TMEM231,CEP97,CCDC40,FAT4,RASGRF1,RDX,CRTAC1,RET,RFX2,RFX3,KCTD17,ROBO1,ROBO2,GLDN,LRRK2,RXRA,S100B,SEMA6D,ATXN2,LRFN5,KIF27,SGK1,ARX,CPEB3,FUZ,NLGN1,DZIP1,ABLIM3,PREX2,BTBD3,CCDC88A,TRIM67,TTC17,IFT122,SNAP25,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,TROVE2,TTBK2,KANK1,STXBP1,SYT1,COBL,ATMIN,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DNAH7,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TPM1,TSC1,TSC2,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,TBC1D15,P2RY12,WNT7A,CFAP298,ZIC2,NDRG4,TMEM237,DPYSL5,EVI5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,IFT88,SPATA13" GO: Biological Process GO:0022008 neurogenesis 1.25E-21 1.11E-17 1.45E-18 1.41E-17 348 1628 "ACHE,ADCY6,FZD9,ADORA2A,UNC5A,LRFN2,BEND6,AGT,SEMA6A,ALCAM,ALK,BIN1,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,PRX,SPTBN4,ARHGDIA,ARNTL,ASPA,NCOA1,NUMB,ATP2B2,ADGRB1,ADGRB3,BCHE,NRP2,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,MTMR2,GPC2,RAB29,MYRF,IL33,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,SPAG9,CBLN1,CCK,ARHGEF1,CBFA2T2,ARHGEF2,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,ZNF521,CRMP1,AATK,CSF1,CSF1R,RGS6,ARHGEF10,CSNK1E,SIPA1L1,VCAN,CNTNAP2,PLXNA4,SLITRK5,RIMS2,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBI,DBN1,MYEF2,KIAA0319,GSDME,PLPPR4,SNAP91,CHRDL1,DLX1,GRIN3A,DMD,NYAP1,MED12,CDON,SHANK1,DPYSL2,ECM2,WDPCP,EDN3,EDNRB,HEYL,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G1,EIF4G2,EMX2,COQ7,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,ADGRV1,EYA1,NRN1,ACSL4,PTK2B,TUBB3,FKTN,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXO3,EVL,SEMA4D,SYT3,PDLIM5,USP21,DLL3,STAU2,BRSK1,FYN,CHL1,GABRB3,SYT17,DISC1,NTNG2,GLI2,DCLK2,GNAO1,GPER1,STMN2,CIT,GSN,RNF165,SOX21,LINGO1,NEGR1,IGF1,NKD1,RBPJ,KNDC1,IL6ST,INSM1,ITGAM,ITPKA,JAK2,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIG4,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MARK1,MATN2,MBD1,MBP,MEF2C,MEIS1,AFDN,GIT1,DBNL,BLOC1S2,ADAM22,NRBP2,MYCN,MYO6,MYO7A,NBL1,NEFM,NEFH,NF1,NFE2L2,NFIX,NNAT,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OPA1,P2RY1,PALM,PAX6,ENPP2,GPR173,NLGN3,SEMA5B,PLXNB1,PMP22,SDK2,MBOAT7,FA2H,PPP3CA,MAPK3,MAPK9,RELN,KLK6,PSD,LAMA1,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PEX2,STRC,SH3TC2,FAT4,ROGDI,RASGRF1,CRTAC1,RET,ROBO1,ROBO2,RORB,GLDN,LRRK2,ATAT1,RTN1,RXRA,S100B,SALL1,SEMA6D,ATXN2,LRFN5,SGK1,ARX,CPEB3,NLGN1,PREX2,BTBD3,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SMARCA4,SMARCC2,CDK5RAP2,SMARCD3,SNAP25,FAIM2,MYO16,USP33,SOX3,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,MESP1,ZC4H2,KANK1,STXBP1,SYT1,COBL,TACC1,TAL1,ADGRL3,AGTPBP1,TCF4,SATB2,CUX2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,PARD3,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,MTCH1,VLDLR,P2RY12,WNT7A,XRCC4,LGI4,ZIC2,NDRG4,DPYSL5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,IFT88" GO: Biological Process GO:0048858 cell projection morphogenesis 1.32E-21 1.16E-17 1.45E-18 1.41E-17 223 904 "ACHE,ADORA2A,UNC5A,LRFN2,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NUMB,DYNLL1,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,ARHGEF7,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,EVI5L,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,CCDC151,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,RIMS2,USP6NL,BOC,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,PLPPR4,SNAP91,DMD,NYAP1,SHANK1,DPYSL2,ECM2,WDPCP,SEMA3D,CELSR3,EGFR,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,TUBB3,ZMYND10,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,TMEM107,PDLIM5,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,SEPT9,NTNG2,GLI2,CIT,GSN,RNF165,RABL2A,LINGO1,PACSIN2,KNDC1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,POC1B,DBNL,NBL1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,PAX6,ENPP2,NLGN3,SEMA5B,SNX10,PLXNB1,PPP3CA,CEP41,MAPK3,HYDIN,RELN,PTK2,PTPRD,PTPRO,TMEM231,CEP97,CCDC40,RET,RFX2,RFX3,KCTD17,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,ATXN2,LRFN5,KIF27,SGK1,ARX,FUZ,NLGN1,DZIP1,ABLIM3,PREX2,BTBD3,IFT122,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,TROVE2,TTBK2,KANK1,STXBP1,SYT1,COBL,ATMIN,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,DNAH7,DICER1,TIAM1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,TBC1D15,WNT7A,CFAP298,ZIC2,TMEM237,DPYSL5,EVI5,PRDM8,SEMA3B,FZD3,RTN4,IFT88" GO: Biological Process GO:0032989 cellular component morphogenesis 2.24E-21 1.98E-17 2.20E-18 2.13E-17 314 1430 "ACHE,ACTN1,FMNL2,ADD1,AXIN2,ADORA2A,UNC5A,LRFN2,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,ANK2,SEMA7A,FGD2,APBB2,APC,EPB41L5,GAS7,CPNE5,SHROOM2,SEMA4G,PRX,SPTBN4,ARHGDIA,NUMB,DYNLL1,ATP2B2,ADAM15,ADGRB1,ADGRB3,BBS2,NRP2,CFLAR,BMP7,BMPR1B,ARHGEF7,MTMR2,WASF1,LDLRAD4,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,CAPN3,ISPD,CCK,ARHGEF1,ARHGEF2,SEPT7,CDH2,DCLK1,ZMYM4,EVI5L,NOG,NUMBL,CFL2,CHN1,TAOK2,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,CCDC151,AKAP5,TBPL1,ZNF385A,CRMP1,AATK,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,SLITRK5,RIMS2,USP6NL,BOC,MYADM,KIF26A,TBC1D5,KIAA0586,IST1,DAPK3,DBN1,PLPPR4,SNAP91,DMD,NYAP1,SHANK1,DPYSL2,ECM2,DNM1L,FIS1,WDPCP,EDN1,HEYL,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G2,EPB41,EPB41L2,COQ7,EPHB1,ERBB2,ERCC2,CDKL3,ETV1,NRN1,TBC1D16,PTK2B,TUBB3,DLC1,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FOXF2,EVL,SEMA4D,SYT3,TMEM107,PDLIM5,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,SEPT9,GCNT2,NTNG2,TTBK1,GLI2,LOXL3,FERMT2,CIT,GSN,RNF165,BVES,RABL2A,LINGO1,HAS2,PACSIN2,AGFG1,RBPJ,KNDC1,ITGA7,ITPKA,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIMS1,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,MKLN1,DBNL,MYH3,MYO7A,NBL1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,P2RX7,PALM,PAX6,ENPP2,TMOD2,NLGN3,SEMA5B,SNX10,PLXNB1,PMP22,SH3KBP1,PPP3CA,CEP41,MAPK3,MAPK9,FITM2,HYDIN,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,STRC,TMEM231,PID1,CEP97,CCDC40,RDX,RET,RFX2,RFX3,KCTD17,ROBO1,ROBO2,LRRK2,AP1AR,S100B,SALL1,SEMA6D,ATXN2,LRFN5,KIF27,SGK1,ARX,FUZ,FHOD3,ST6GAL1,NLGN1,DZIP1,NUBPL,ABLIM3,PREX2,BTBD3,RADIL,SMARCA4,IFT122,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,TROVE2,LARP4,SS18,TTBK2,PHLDB1,KANK1,STXBP1,ARC,SYT1,COBL,TAL1,ATMIN,CUX2,RPGRIP1L,CLASP1,SZT2,SYNE1,OBSL1,FRYL,TEK,DNAH7,DICER1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TPM1,TTC3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,TBC1D15,WIPF1,WNT7A,CFAP298,ZIC2,CRB2,TMEM237,DPYSL5,MFF,EVI5,PRDM8,SEMA3B,FZD3,RTN4,JMJD1C,FRMD6,IFT88" GO: Biological Process GO:0000902 cell morphogenesis 4.14E-20 3.66E-16 3.66E-17 3.54E-16 294 1337 "ACHE,ACTN1,FMNL2,ADD1,AXIN2,ADORA2A,UNC5A,LRFN2,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,SEMA7A,FGD2,APBB2,APC,EPB41L5,GAS7,CPNE5,SHROOM2,SEMA4G,SPTBN4,ARHGDIA,NUMB,DYNLL1,ATP2B2,ADAM15,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,ARHGEF7,WASF1,LDLRAD4,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,ARHGEF2,SEPT7,CDH2,DCLK1,ZMYM4,EVI5L,NOG,NUMBL,CHN1,TAOK2,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,CCDC151,AKAP5,ZNF385A,CRMP1,AATK,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,SLITRK5,RIMS2,USP6NL,BOC,MYADM,KIF26A,TBC1D5,KIAA0586,IST1,DAPK3,DBN1,PLPPR4,SNAP91,DMD,NYAP1,SHANK1,DPYSL2,ECM2,WDPCP,HEYL,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G2,EPB41,EPB41L2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,PTK2B,TUBB3,DLC1,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FOXF2,EVL,SEMA4D,SYT3,TMEM107,PDLIM5,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,SEPT9,GCNT2,NTNG2,TTBK1,GLI2,LOXL3,FERMT2,CIT,GSN,RNF165,BVES,RABL2A,LINGO1,HAS2,PACSIN2,RBPJ,KNDC1,ITGA7,ITPKA,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIMS1,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,MKLN1,DBNL,MYO7A,NBL1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,P2RX7,PALM,PAX6,ENPP2,NLGN3,SEMA5B,SNX10,PLXNB1,SH3KBP1,PPP3CA,CEP41,MAPK3,MAPK9,FITM2,HYDIN,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,STRC,TMEM231,CEP97,CCDC40,RDX,RET,RFX2,RFX3,KCTD17,ROBO1,ROBO2,LRRK2,AP1AR,S100B,SALL1,SEMA6D,ATXN2,LRFN5,KIF27,SGK1,ARX,FUZ,ST6GAL1,NLGN1,DZIP1,ABLIM3,PREX2,BTBD3,RADIL,SMARCA4,IFT122,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,TROVE2,LARP4,SS18,TTBK2,PHLDB1,KANK1,STXBP1,ARC,SYT1,COBL,TAL1,ATMIN,CUX2,RPGRIP1L,CLASP1,SZT2,SYNE1,OBSL1,FRYL,TEK,DNAH7,DICER1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TPM1,TTC3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,TBC1D15,WIPF1,WNT7A,CFAP298,ZIC2,CRB2,TMEM237,DPYSL5,EVI5,PRDM8,SEMA3B,FZD3,RTN4,JMJD1C,FRMD6,IFT88" GO: Biological Process GO:0048699 generation of neurons 7.91E-20 6.99E-16 6.36E-17 6.14E-16 325 1528 "ACHE,ADCY6,FZD9,ADORA2A,UNC5A,LRFN2,BEND6,SEMA6A,ALCAM,ALK,BIN1,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,ARNTL,ASPA,NCOA1,NUMB,ATP2B2,ADGRB1,ADGRB3,BCHE,NRP2,PROM1,BMP7,BMPR1B,SYNJ1,MTMR2,GPC2,RAB29,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,SPAG9,CBLN1,CCK,ARHGEF1,CBFA2T2,ARHGEF2,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,ZNF521,CRMP1,AATK,CSF1,CSF1R,RGS6,CSNK1E,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,RIMS2,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBN1,MYEF2,KIAA0319,GSDME,PLPPR4,SNAP91,CHRDL1,DLX1,GRIN3A,DMD,NYAP1,CDON,SHANK1,DPYSL2,ECM2,WDPCP,EDN3,EDNRB,HEYL,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G1,EIF4G2,EMX2,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,ADGRV1,EYA1,NRN1,ACSL4,PTK2B,TUBB3,FKTN,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXO3,EVL,SEMA4D,SYT3,PDLIM5,USP21,DLL3,STAU2,BRSK1,FYN,CHL1,GABRB3,SYT17,DISC1,NTNG2,GLI2,DCLK2,GNAO1,GPER1,STMN2,CIT,RNF165,SOX21,LINGO1,NEGR1,NKD1,RBPJ,KNDC1,IL6ST,INSM1,ITPKA,JAK2,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIG4,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MARK1,MATN2,MBD1,MBP,MEF2C,MEIS1,AFDN,GIT1,DBNL,BLOC1S2,NRBP2,MYCN,MYO6,MYO7A,NBL1,NEFM,NEFH,NF1,NFE2L2,NFIX,NNAT,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,ENPP2,GPR173,NLGN3,SEMA5B,PLXNB1,PMP22,SDK2,PPP3CA,MAPK3,MAPK9,RELN,KLK6,PSD,LAMA1,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PEX2,STRC,FAT4,RASGRF1,CRTAC1,RET,ROBO1,ROBO2,RORB,GLDN,LRRK2,ATAT1,RTN1,RXRA,S100B,SALL1,SEMA6D,ATXN2,LRFN5,SGK1,ARX,CPEB3,NLGN1,PREX2,BTBD3,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SMARCC2,CDK5RAP2,SMARCD3,SNAP25,FAIM2,MYO16,USP33,SOX3,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,ZC4H2,KANK1,STXBP1,SYT1,COBL,TAL1,ADGRL3,AGTPBP1,TCF4,SATB2,CUX2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,MTCH1,VLDLR,P2RY12,WNT7A,XRCC4,LGI4,ZIC2,NDRG4,DPYSL5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,IFT88" GO: Biological Process GO:0048812 neuron projection morphogenesis 1.21E-19 1.07E-15 8.88E-17 8.58E-16 167 630 "ACHE,ADORA2A,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CACNA1A,DDR1,KALRN,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,RIMS2,BOC,KIF26A,IST1,DBN1,PLPPR4,SNAP91,NYAP1,SHANK1,DPYSL2,ECM2,SEMA3D,CELSR3,EGFR,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,PDLIM5,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,NTNG2,GLI2,CIT,RNF165,LINGO1,KNDC1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAP2,MAP6,MAPT,MATN2,MBP,DBNL,NBL1,NEFH,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,PAX6,NLGN3,SEMA5B,PLXNB1,PPP3CA,MAPK3,RELN,PTK2,PTPRD,PTPRO,RET,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,ATXN2,LRFN5,SGK1,ARX,NLGN1,PREX2,BTBD3,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,STXBP1,SYT1,COBL,CUX2,SZT2,SYNE1,OBSL1,DICER1,TIAM1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,WNT7A,ZIC2,DPYSL5,PRDM8,SEMA3B,FZD3,RTN4" GO: Biological Process GO:0030182 neuron differentiation 3.63E-19 3.21E-15 2.47E-16 2.38E-15 301 1398 "ACHE,ADCY6,ADORA2A,UNC5A,LRFN2,BEND6,SEMA6A,ALCAM,ALK,BIN1,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NCOA1,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,PROM1,BMP7,BMPR1B,MTMR2,GPC2,RAB29,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,SPAG9,CBLN1,CCK,ARHGEF1,CBFA2T2,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,ZNF521,CRMP1,AATK,CSF1R,RGS6,CSNK1E,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,RIMS2,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBN1,MYEF2,KIAA0319,GSDME,PLPPR4,SNAP91,CHRDL1,DLX1,GRIN3A,DMD,NYAP1,CDON,SHANK1,DPYSL2,ECM2,WDPCP,EDN3,EDNRB,HEYL,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G1,EIF4G2,EMX2,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,ADGRV1,EYA1,NRN1,ACSL4,PTK2B,TUBB3,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXO3,EVL,SEMA4D,SYT3,PDLIM5,USP21,STAU2,BRSK1,FYN,CHL1,GABRB3,SYT17,DISC1,NTNG2,GLI2,DCLK2,GNAO1,STMN2,CIT,RNF165,SOX21,LINGO1,NEGR1,NKD1,RBPJ,KNDC1,INSM1,ITPKA,JAK2,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBD1,MBP,MEF2C,MEIS1,GIT1,DBNL,BLOC1S2,NRBP2,MYCN,MYO6,MYO7A,NBL1,NEFM,NEFH,NF1,NFE2L2,NFIX,NNAT,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,NLGN3,SEMA5B,PLXNB1,PMP22,SDK2,PPP3CA,MAPK3,MAPK9,RELN,KLK6,PSD,LAMA1,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,STRC,FAT4,RASGRF1,CRTAC1,RET,ROBO1,ROBO2,RORB,GLDN,LRRK2,ATAT1,RTN1,RXRA,S100B,SALL1,SEMA6D,ATXN2,LRFN5,SGK1,ARX,CPEB3,NLGN1,PREX2,BTBD3,CDK5RAP3,CCDC88A,TRIM67,SMARCC2,CDK5RAP2,SNAP25,FAIM2,MYO16,USP33,SOX3,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,ZC4H2,KANK1,STXBP1,SYT1,COBL,TAL1,AGTPBP1,TCF4,SATB2,CUX2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,MTCH1,VLDLR,WNT7A,LGI4,ZIC2,NDRG4,DPYSL5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,IFT88" GO: Biological Process GO:0048667 cell morphogenesis involved in neuron differentiation 6.48E-18 5.73E-14 4.09E-15 3.95E-14 155 590 "ACHE,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,SEMA4G,SPTBN4,ARHGDIA,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CACNA1A,KALRN,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,NRXN3,NGEF,VAX2,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,BOC,KIF26A,IST1,DBN1,PLPPR4,SNAP91,SHANK1,DPYSL2,ECM2,WDPCP,SEMA3D,CELSR3,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,SEC24B,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,PDLIM5,STAU2,BRSK1,FYN,CHL1,DISC1,NTNG2,GLI2,CIT,RNF165,LINGO1,KNDC1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,MAP2,MAP6,MAPT,MATN2,MBP,MEF2C,MYO7A,NEFH,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,PAX6,NLGN3,SEMA5B,PLXNB1,PPP3CA,MAPK3,RELN,PTK2,PTPRD,PTPRO,STRC,RET,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,LRFN5,SGK1,ARX,NLGN1,PREX2,BTBD3,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,STXBP1,COBL,CUX2,SZT2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,FLRT2,VLDLR,WNT7A,ZIC2,DPYSL5,PRDM8,SEMA3B,FZD3,RTN4" GO: Biological Process GO:0031175 neuron projection development 1.17E-17 1.03E-13 6.89E-15 6.66E-14 220 953 "ACHE,ADCY6,ADORA2A,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,RAB29,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,CBFA2T2,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,RIMS2,BOC,KIF26A,IST1,DBN1,KIAA0319,PLPPR4,SNAP91,GRIN3A,DMD,NYAP1,SHANK1,DPYSL2,ECM2,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,ACSL4,PTK2B,TUBB3,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,PDLIM5,USP21,STAU2,BRSK1,FYN,CHL1,SYT17,DISC1,NTNG2,GLI2,GNAO1,STMN2,CIT,RNF165,LINGO1,NEGR1,RBPJ,KNDC1,ITPKA,JAK2,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,GIT1,DBNL,BLOC1S2,MYO6,NBL1,NEFM,NEFH,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,MAPK3,MAPK9,RELN,KLK6,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,RASGRF1,CRTAC1,RET,ROBO1,ROBO2,LRRK2,RXRA,S100B,SEMA6D,ATXN2,LRFN5,SGK1,ARX,CPEB3,NLGN1,PREX2,BTBD3,CCDC88A,TRIM67,SNAP25,MYO16,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,KANK1,STXBP1,SYT1,COBL,CUX2,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,TIAM1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,UGT8,FLRT2,VLDLR,WNT7A,ZIC2,NDRG4,DPYSL5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4" GO: Biological Process GO:0050804 modulation of chemical synaptic transmission 6.03E-17 5.33E-13 3.33E-14 3.22E-13 107 357 "SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,AGT,PPFIA3,ARRB2,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1A,CACNA1B,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CD38,DGKI,CACNA2D2,CHRNA4,CNR1,PICK1,CRHBP,SNCAIP,SIPA1L1,RIMS4,RIMS2,DAPK1,DBI,DBN1,DNM1,DMPK,SHANK1,EDN1,EDN3,EGFR,ERBB4,PTK2B,FGF14,BAIAP2,CSPG5,STAU2,GABBR1,CPLX2,PCDH17,PPARGC1A,GLUL,KCNMB4,GPER1,GRIA2,GRIK5,GRM2,GRM8,SHISA6,ICA1,MYLK2,LRRTM1,ITPKA,KCNB1,KIT,LAMA2,MAPT,MEF2C,MYO6,NF1,NTRK2,OXTR,NLGN3,PLCL1,PPP3CA,RELN,PTK2,PTN,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,CPEB3,NLGN1,NAPB,SNAP25,SNCA,IQSEC2,CLSTN2,STAU1,STX1A,STXBP1,SYN1,ARC,SYP,SYT1,TACR1,CUX2,CRTC1,NR2E1,VGF,WNT7A,CELF4,NETO2,NETO1,JPH3" GO: Biological Process GO:0048666 neuron development 7.90E-17 6.98E-13 4.11E-14 3.97E-13 245 1114 "ACHE,ADCY6,ADORA2A,UNC5A,LRFN2,SEMA6A,ALCAM,ALK,LRFN1,SEMA7A,APBB2,APC,GAS7,CPNE5,SEMA4G,SPTBN4,ARHGDIA,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,MTMR2,RAB29,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,CBFA2T2,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,CPNE6,NRXN3,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,CRMP1,AATK,CSF1R,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,RIMS2,BOC,KIF26A,IST1,DGKG,DBN1,KIAA0319,PLPPR4,SNAP91,GRIN3A,DMD,NYAP1,SHANK1,DPYSL2,ECM2,WDPCP,EDNRB,SEMA3D,FRY,CELSR3,EGFR,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,ADGRV1,NRN1,ACSL4,PTK2B,TUBB3,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,EVL,SEMA4D,SYT3,PDLIM5,USP21,STAU2,BRSK1,FYN,CHL1,GABRB3,SYT17,DISC1,NTNG2,GLI2,DCLK2,GNAO1,STMN2,CIT,RNF165,LINGO1,NEGR1,RBPJ,KNDC1,INSM1,ITPKA,JAK2,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIFR,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,GIT1,DBNL,BLOC1S2,MYO6,MYO7A,NBL1,NEFM,NEFH,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,MAPK3,MAPK9,RELN,KLK6,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,STRC,FAT4,RASGRF1,CRTAC1,RET,ROBO1,ROBO2,RORB,GLDN,LRRK2,ATAT1,RXRA,S100B,SEMA6D,ATXN2,LRFN5,SGK1,ARX,CPEB3,NLGN1,PREX2,BTBD3,CCDC88A,TRIM67,SNAP25,MYO16,USP33,SOX3,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,KANK1,STXBP1,SYT1,COBL,CUX2,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,UCHL1,GORASP1,UGT8,FLRT2,MTCH1,VLDLR,WNT7A,LGI4,ZIC2,NDRG4,DPYSL5,GDPD5,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,IFT88" GO: Biological Process GO:0007417 central nervous system development 2.82E-16 2.49E-12 1.38E-13 1.34E-12 224 1002 "ABR,NDRG2,ADORA2A,PCDH19,AGT,NME5,AK2,BIN1,OGT,SEMA7A,APAF1,APLP1,SHROOM2,SPTBN4,ARRB2,ASPA,CHRD,NCOA1,NUMB,DYNLL1,ATP2B2,ADAM23,BBS2,NRP2,BID,MYRF,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,SYNGR3,CDH2,DCLK1,NOG,NUMBL,SLIT2,LHX2,TPP1,VAX2,QKI,CNTN1,WHRN,AKAP5,HAPLN1,NCOR1,NCOR2,AATK,CSF1R,VCAN,CNTNAP2,PLXNA4,SLITRK5,SNPH,DBI,SEC16A,DLX1,MED12,CDON,DPYSL2,DRP2,RCAN1,SEZ6L2,EGFR,EMX2,EPHB1,ERBB2,ERBB4,ERCC2,EZH1,DLC1,PRMT5,SEC24B,FGF13,FGFR1,FGFR3,HPCAL4,FOXO3,AFF2,AK8,DLL3,FYN,DISC1,PPARGC1A,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,GSN,LINGO1,PADI2,HNMT,IGF1,ZIC5,RBPJ,KNDC1,IL6ST,SLC6A17,ITGAM,KCNK3,STMN1,LIG4,SMAD1,SMAD9,MAP2,MAPT,MBD1,MBP,SHC3,AFDN,ADAM22,TAGLN3,MYCN,NEFH,NF1,NFIX,NNAT,NPY,NOVA1,NPTX1,NRCAM,NTRK2,NTRK3,OXTR,PAX6,PCDH9,ENPP2,PFKFB3,NLGN3,SERPINI1,PKD1,PCDH18,MAPKAP1,SEPT4,MBOAT7,FA2H,POU6F1,PPP3CC,MAPK3,MAPK9,HYDIN,RELN,KLK6,PTCH1,PTK2,PTN,FAT4,ROGDI,CRTAC1,ROBO1,ROBO2,RORB,LRRK2,ATAT1,S100B,SALL1,SEMA6D,ATXN2,KIF27,TRA2B,SH3GL3,ARX,FUZ,BTBD3,ZNF430,SLC6A11,SLC8A1,SIRT2,CDK5RAP3,SMARCA4,SMARCC2,CDK5RAP2,IFT122,FAIM2,MYO16,SOX3,SOX11,MYCBP2,SSTR1,SSTR2,ZC4H2,TTBK2,PLCB1,SYT1,TACC1,TAL1,AGTPBP1,SATB2,ZEB1,RPGRIP1L,SZT2,DICER1,CHST8,CDH22,THRA,TIMP4,TLR4,NR2E1,TP53BP2,NR2C2,TSC1,UBE3A,UGT8,CCDC14,VLDLR,WNT7A,WRN,XRCC4,ZIC1,ZIC2,NDRG4,SPHK2,GDPD5,PRDM8,RNF103,SLC17A7,KCNAB1,FZD3,RTN4,IFT88" GO: Biological Process GO:0043087 regulation of GTPase activity 1.08E-15 9.52E-12 5.01E-13 4.84E-12 167 688 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,AMPH,BIN1,FGD2,PKP4,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,ARRB2,DOCK11,ADGRB3,RGS11,RGS9,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,ARHGEF25,RGN,ARHGEF1,DGKI,ARHGEF2,ARHGAP33,EVI5L,CCPG1,RCBTB2,CHN1,CHN2,ARHGAP22,SLIT2,NGEF,ARHGEF6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ELMO1,TIAM2,SGSM2,CPEB2,DOCK2,RASGRP1,FAM13A,EGFR,RASA4,EIF5,TNK2,RGS17,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,PSD2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GNAO1,ADAP1,GRIN2C,GRIN2D,BVES,FICD,NCKAP1L,ARHGAP36,AGFG1,SMAP1,KNDC1,INPP5B,JAK2,KIT,IPO5,STXBP5,LIMS1,SHC3,KITLG,AFDN,GIT1,MYO9A,NF1,NTRK2,NTRK3,TBC1D25,OCRL,PLXNB1,RASGEF1B,PSD,BCAS3,PTK2,PTPRN2,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RDX,RET,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,SBF1,FNIP1,RASA3,ASAP3,PREX2,ARHGEF40,ARFGAP1,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,PLCB1,MLST8,MCF2L,DNMBP,DOCK9,ARHGAP9,TEK,TIAM1,TRIO,TSC1,TSC2,VAV1,TBC1D15,P2RY12,RICTOR,EVI5,DOCK8,SPATA13" GO: Biological Process GO:0000904 cell morphogenesis involved in differentiation 2.25E-15 1.98E-11 9.92E-13 9.59E-12 193 840 "ACHE,ACTN1,AXIN2,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,EPB41L5,SEMA4G,SPTBN4,ARHGDIA,NUMB,ATP2B2,ADAM15,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,ARHGEF7,LDLRAD4,CACNA1A,KALRN,CAMK2A,CAMK2B,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,NRXN3,NGEF,VAX2,AKAP5,ZNF385A,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,BOC,MYADM,KIF26A,IST1,DBN1,PLPPR4,SNAP91,SHANK1,DPYSL2,ECM2,WDPCP,HEYL,SEMA3D,CELSR3,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FOXF2,EVL,SEMA4D,PDLIM5,STAU2,BRSK1,FYN,CHL1,DISC1,GCNT2,NTNG2,GLI2,LOXL3,FERMT2,CIT,RNF165,BVES,LINGO1,HAS2,RBPJ,KNDC1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,LIMS1,MAP2,MAP6,MAPT,MATN2,MBP,MEF2C,MYO7A,NEFH,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,PAX6,ENPP2,NLGN3,SEMA5B,PLXNB1,PPP3CA,MAPK3,MAPK9,RELN,PTK2,PTPRD,PTPRO,STRC,RET,ROBO1,ROBO2,LRRK2,AP1AR,S100B,SALL1,SEMA6D,LRFN5,SGK1,ARX,FUZ,ST6GAL1,NLGN1,PREX2,BTBD3,RADIL,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,PHLDB1,KANK1,STXBP1,COBL,TAL1,CUX2,CLASP1,SZT2,SYNE1,OBSL1,TEK,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TTC3,UCHL1,GORASP1,FLRT2,VLDLR,WNT7A,ZIC2,CRB2,DPYSL5,PRDM8,SEMA3B,FZD3,RTN4,JMJD1C,FRMD6,IFT88" GO: Biological Process GO:0051960 regulation of nervous system development 1.99E-14 1.75E-10 8.08E-12 7.81E-11 197 881 "ACHE,ADCY6,BEND6,SEMA6A,BIN1,SEMA7A,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASPA,CHRD,NCOA1,NUMB,ADGRB1,ADGRB2,ADGRB3,BMP7,SYNJ1,MTMR2,RAB29,MYRF,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,CBLN1,ARHGEF1,CBFA2T2,ARHGEF2,CDH2,NOG,NUMBL,CHN1,SLIT2,CPNE6,NRXN3,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1,RGS6,SIPA1L1,PLXNA4,SLITRK5,RIMS2,IST1,BRINP1,DBN1,KIAA0319,DLX1,DMD,CDON,SHANK1,DPYSL2,EDNRB,HEYL,SEMA3D,PLXNC1,EIF4G1,EIF4G2,EPHB1,ERBB4,CDKL3,EYA1,PTK2B,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXO3,SEMA4D,SYT3,PDLIM5,DLL3,STAU2,FYN,SYT17,DISC1,GLI2,GPER1,STMN2,CIT,SOX21,LINGO1,NEGR1,IGF1,RBPJ,KNDC1,IL6ST,LRRTM1,ITPKA,KIT,L1CAM,LIG4,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,MYCN,NBL1,NF1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,PALM,PAX6,ENPP2,GPR173,NLGN3,SEMA5B,PLXNB1,PMP22,LRRN3,PPP3CA,PRKACB,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,RET,ROBO1,ROBO2,LRRK2,RXRA,SALL1,SEMA6D,SGK1,CPEB3,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,CDK5RAP2,SMARCD3,IFT122,SNAP25,SOX3,SOX11,SPP1,KDM4C,SPART,CLASP2,CLSTN2,KANK1,SYT1,COBL,ADGRL3,TCF4,CUX2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,GPR161,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,LRRC24,TTC3,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,GDPD5,SEMA3B,ITM2C,FZD3,RTN4" GO: Biological Process GO:0022604 regulation of cell morphogenesis 2.01E-14 1.78E-10 8.08E-12 7.81E-11 149 609 "ACHE,FMNL2,AXIN2,TBC1D14,SEMA6A,SEMA7A,FGD2,EPB41L5,GAS7,CPNE5,SEMA4G,ARHGDIA,NUMB,ADGRB3,ARHGEF7,LDLRAD4,CFAP410,CACNA1A,KALRN,HAP1,CAMK2B,ARHGEF1,SEPT7,CDH2,ZMYM4,EVI5L,NUMBL,CHN1,TAOK2,SLIT2,CPNE6,NGEF,CCDC151,AKAP5,AATK,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,RIMS2,USP6NL,MYADM,TBC1D5,IST1,DAPK3,DBN1,DPYSL2,WDPCP,SEMA3D,PLXNC1,EIF4G2,EPB41,EPB41L2,CDKL3,TBC1D16,PTK2B,DLC1,OLFM1,FGF13,BAIAP2,MAD2L2,SEMA4D,SYT3,PDLIM5,STAU2,FYN,SYT17,DISC1,SEPT9,GCNT2,TTBK1,FERMT2,CIT,BVES,LINGO1,HAS2,KNDC1,ITGA7,ITPKA,KIT,L1CAM,LIMS1,MAP2,MAP4,MAPT,MBP,MKLN1,NRCAM,NTRK2,NTRK3,PALM,ENPP2,NLGN3,SEMA5B,PLXNB1,SH3KBP1,PPP3CA,MAPK9,FITM2,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,CEP97,RDX,RET,KCTD17,ROBO1,ROBO2,LRRK2,AP1AR,S100B,SALL1,SEMA6D,SGK1,FUZ,ST6GAL1,NLGN1,SPP1,SPART,PBLD,CLASP2,LARP4,TTBK2,PHLDB1,KANK1,ARC,SYT1,CUX2,CLASP1,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,TPM1,TTC3,GORASP1,TBC1D15,WIPF1,WNT7A,CRB2,EVI5,SEMA3B,RTN4,IFT88" GO: Biological Process GO:0043547 positive regulation of GTPase activity 2.29E-14 2.02E-10 8.79E-12 8.49E-11 153 632 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,AMPH,BIN1,FGD2,PKP4,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,DOCK11,ADGRB3,RGS11,RGS9,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,ARHGEF25,RGN,ARHGEF1,ARHGEF2,ARHGAP33,EVI5L,RCBTB2,CHN1,CHN2,ARHGAP22,NGEF,ARHGEF6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ELMO1,TIAM2,SGSM2,DOCK2,RASGRP1,FAM13A,EGFR,RASA4,EIF5,RGS17,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,PSD2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GNAO1,ADAP1,GRIN2C,GRIN2D,NCKAP1L,ARHGAP36,AGFG1,SMAP1,KNDC1,INPP5B,JAK2,KIT,STXBP5,LIMS1,SHC3,KITLG,AFDN,GIT1,MYO9A,NF1,NTRK3,TBC1D25,OCRL,PLXNB1,RASGEF1B,PSD,BCAS3,PTK2,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS12,RIC8B,SGSM1,LRRK2,SBF1,FNIP1,RASA3,ASAP3,PREX2,ARHGEF40,ARFGAP1,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,PLCB1,MCF2L,DNMBP,DOCK9,ARHGAP9,TEK,TIAM1,TRIO,TSC1,TSC2,VAV1,TBC1D15,P2RY12,EVI5,DOCK8,SPATA13" GO: Biological Process GO:0007409 axonogenesis 5.75E-14 5.08E-10 2.12E-11 2.04E-10 123 475 "ACHE,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,NRP2,BMP7,BMPR1B,CACNA1A,KALRN,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,NRXN3,VAX2,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,BOC,KIF26A,IST1,DBN1,PLPPR4,SNAP91,DPYSL2,ECM2,SEMA3D,CELSR3,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,BRSK1,FYN,CHL1,DISC1,NTNG2,GLI2,RNF165,LINGO1,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,MAP2,MAPT,MATN2,MBP,NEFH,NPTX1,NRCAM,NTRK2,NTRK3,PAX6,NLGN3,SEMA5B,PLXNB1,MAPK3,RELN,PTK2,PTPRO,RET,ROBO1,ROBO2,S100B,SEMA6D,LRFN5,ARX,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,STXBP1,COBL,SZT2,TIAM1,NR2E1,PARD3,UCHL1,FLRT2,WNT7A,ZIC2,DPYSL5,PRDM8,SEMA3B,FZD3,RTN4" GO: Biological Process GO:0007267 cell-cell signaling 1.27E-13 1.12E-09 4.50E-11 4.35E-10 253 1233 "SYN3,ASIC1,ACHE,ABHD6,ADCY5,ADORA1,ADORA2A,ADRA1D,ADRA1B,LRFN2,ADRB2,AGT,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,AMH,AMPH,LRFN1,ANK2,PPFIA4,PKP4,APBA2,PPFIA3,MADD,CASK,ARNTL,ARRB1,ARRB2,CADPS,PDE8B,ATP2A2,ATP2B2,BCHE,HCN2,SYNJ1,ARHGEF7,BTK,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CBLN1,CD86,CD38,DGKI,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CPNE6,NRXN3,CLCN3,MAP4K4,CNR1,PICK1,AKAP5,MYRIP,CLOCK,CRHBP,CRY2,SNCAIP,SIPA1L1,RIMS4,SLITRK5,RIMS2,SNPH,DAPK1,DBI,DBN1,C2CD2L,LYPD1,SNAP91,SV2B,DNM1,DMPK,SHANK1,SLC12A6,DTNA,EDN1,EDN3,EGFR,EGR3,STX2,ERBB4,PTK2B,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,BAIAP2,SYT3,CSPG5,STAU2,BRSK1,OGA,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,CPLX2,CPLX1,GCK,GDF9,PCDH17,PPARGC1A,GLI2,GLUL,KCNMB4,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,HMGCR,SHISA6,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,JAK2,KCNB1,KCND2,KCNK3,KCNN1,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,MAPT,MBP,SHC3,MEF2C,AFDN,MYO5A,MYO6,MYT1,NDP,NELL2,NF1,NNAT,NPY,NOVA1,NPTX1,NPTX2,NTRK2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PCDH8,PCSK1,PCSK5,PDE1C,TMOD2,PFKFB2,NLGN3,PLCL1,PMP22,TRHDE,SH3KBP1,PPP3CA,RELN,PTK2,PTN,PTPRD,PTPRN,PTPRN2,RASGRF1,RASGRF2,GAL3ST4,RFX3,LRRK2,STX1B,S100B,LRFN5,SCN2B,SMPD3,CPEB3,SYBU,NLGN1,SLC6A11,SLC12A4,NAPB,SNAP25,SNCA,SOX11,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,STXBP1,PLCB1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,TACR1,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,TEK,SIRT1,TIAM1,NR2E1,RASD2,STXBP4,TRPM2,KCNE5,VGF,VIPR2,VSNL1,WNT7A,TRIM9,CELF4,SEMA3B,SLC17A7,GJC2,NETO2,NETO1,JPH3" GO: Biological Process GO:0061564 axon development 1.67E-13 1.48E-09 5.69E-11 5.50E-10 129 514 "ACHE,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,SEMA7A,APBB2,APC,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,NRP2,BMP7,BMPR1B,CACNA1A,DDR1,KALRN,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,NOG,NUMBL,CHN1,SLIT2,LHX2,NRXN3,VAX2,CNR1,CRMP1,AATK,CSF1R,SIPA1L1,PLXNA4,SLITRK5,BOC,KIF26A,IST1,DBN1,PLPPR4,SNAP91,DPYSL2,ECM2,SEMA3D,CELSR3,PLXNC1,EIF4G2,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,EVL,SEMA4D,BRSK1,FYN,CHL1,DISC1,NTNG2,GLI2,RNF165,LINGO1,JAK2,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,MAP2,MAPT,MATN2,MBP,NEFM,NEFH,NPTX1,NRCAM,NTRK2,NTRK3,PAX6,NLGN3,SEMA5B,PLXNB1,MAPK3,RELN,PTK2,PTPRO,CRTAC1,RET,ROBO1,ROBO2,RXRA,S100B,SEMA6D,LRFN5,ARX,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,STXBP1,COBL,SZT2,TIAM1,NR2E1,PARD3,UCHL1,FLRT2,WNT7A,ZIC2,DPYSL5,PRDM8,SEMA3B,FZD3,RTN4" GO: Biological Process GO:0050767 regulation of neurogenesis 7.33E-13 6.48E-09 2.40E-10 2.32E-09 175 784 "ACHE,ADCY6,BEND6,SEMA6A,BIN1,SEMA7A,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASPA,NCOA1,NUMB,ADGRB3,BMP7,SYNJ1,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,ARHGEF2,CDH2,NOG,NUMBL,CHN1,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1,RGS6,SIPA1L1,PLXNA4,RIMS2,IST1,BRINP1,DBN1,KIAA0319,DLX1,DMD,CDON,SHANK1,DPYSL2,EDNRB,HEYL,SEMA3D,PLXNC1,EIF4G1,EIF4G2,ERBB4,CDKL3,EYA1,PTK2B,PRMT5,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXO3,SEMA4D,SYT3,PDLIM5,DLL3,STAU2,FYN,SYT17,DISC1,GLI2,GPER1,STMN2,CIT,SOX21,LINGO1,NEGR1,RBPJ,KNDC1,IL6ST,ITPKA,KIT,L1CAM,LIG4,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,MYCN,NBL1,NF1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,ENPP2,GPR173,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,RET,ROBO1,ROBO2,LRRK2,SALL1,SEMA6D,SGK1,CPEB3,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,CDK5RAP2,SMARCD3,SNAP25,SOX3,SOX11,SPP1,KDM4C,SPART,CLASP2,KANK1,SYT1,COBL,TCF4,CUX2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,TTC3,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,GDPD5,SEMA3B,ITM2C,FZD3,RTN4" GO: Biological Process GO:0099643 signal release from synapse 1.15E-12 1.01E-08 3.50E-10 3.38E-09 57 163 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,DGKI,NRXN3,SNCAIP,RIMS4,RIMS2,SNPH,SNAP91,EDN3,STX2,SYT3,BRSK1,GAD1,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,ICA1,C2CD4C,SYTL4,MEF2C,NF1,NTRK2,P2RX7,PTPRN2,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0007269 neurotransmitter secretion 1.15E-12 1.01E-08 3.50E-10 3.38E-09 57 163 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,DGKI,NRXN3,SNCAIP,RIMS4,RIMS2,SNPH,SNAP91,EDN3,STX2,SYT3,BRSK1,GAD1,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,ICA1,C2CD4C,SYTL4,MEF2C,NF1,NTRK2,P2RX7,PTPRN2,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0060284 regulation of cell development 1.42E-12 1.25E-08 4.17E-10 4.03E-09 208 985 "ACHE,ADCY6,AXIN2,BEND6,SEMA6A,BIN1,SEMA7A,PI16,EPB41L5,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASPA,NCOA1,NUMB,ADGRB3,BMP7,SYNJ1,ARHGEF7,RAB29,LDLRAD4,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,ARHGEF2,CDH2,NOG,NUMBL,CHN1,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP6,AKAP5,CLOCK,CRMP1,AATK,CSF1,RGS6,SIPA1L1,PLXNA4,RIMS2,HDAC9,MYADM,HDAC4,IST1,BRINP1,DBN1,KIAA0319,DLX1,DMD,CDON,SHANK1,DPYSL2,EDN1,EDNRB,HEYL,SEMA3D,PLXNC1,EIF4G1,EIF4G2,ERBB4,CDKL3,EYA1,PTK2B,PRMT5,SLC9B2,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,FOXO3,SEMA4D,SYT3,PDLIM5,DLL3,STAU2,FYN,SYT17,DISC1,GCNT2,GLI2,KDM2B,GPER1,STMN2,CIT,SOX21,LINGO1,HAS2,NEGR1,IGF1,RBPJ,KNDC1,IL6ST,ITPKA,KIT,L1CAM,LIG4,LIMS1,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,MYCN,NACA,NBL1,NF1,NFE2L2,NFYA,NPR2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,PDE3A,ENPP2,GPR173,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,MAPK9,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,RET,RFX3,ROBO1,ROBO2,LRRK2,AP1AR,SALL1,SEMA6D,SGK1,CPEB3,FUZ,ST6GAL1,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,CDK5RAP2,SMARCD3,SNAP25,SOX3,SOX11,KDM3A,SPP1,KDM4C,SPART,PBLD,CLASP2,PHLDB1,KANK1,SYT1,COBL,TAL1,TCF4,CUX2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,TTC3,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,CRB2,GDPD5,SEMA3B,ITM2C,FZD3,RTN4" GO: Biological Process GO:0045664 regulation of neuron differentiation 2.20E-12 1.94E-08 6.27E-10 6.05E-09 151 655 "ACHE,ADCY6,BEND6,SEMA6A,BIN1,SEMA7A,CPNE5,SEMA4G,ARHGDIA,NCOA1,NUMB,ADGRB3,BMP7,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,CDH2,NOG,NUMBL,CHN1,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,RGS6,SIPA1L1,PLXNA4,RIMS2,IST1,BRINP1,DBN1,KIAA0319,DMD,CDON,SHANK1,DPYSL2,EDNRB,HEYL,SEMA3D,PLXNC1,EIF4G1,EIF4G2,CDKL3,EYA1,PTK2B,OLFM1,FGF13,FGFR1,BAIAP2,FOXO3,SEMA4D,SYT3,PDLIM5,STAU2,FYN,SYT17,DISC1,GLI2,STMN2,CIT,SOX21,LINGO1,NEGR1,RBPJ,KNDC1,ITPKA,L1CAM,MAP2,MAPT,MBP,MEF2C,MEIS1,MYCN,NBL1,NF1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,RET,ROBO1,ROBO2,LRRK2,SALL1,SEMA6D,SGK1,CPEB3,NLGN1,CDK5RAP3,CCDC88A,TRIM67,CDK5RAP2,SNAP25,SOX3,SOX11,SPP1,KDM4C,SPART,CLASP2,KANK1,SYT1,COBL,TCF4,CUX2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,TTC3,EIF4ENIF1,GORASP1,VLDLR,WNT7A,NDRG4,GDPD5,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0007610 behavior 7.80E-12 6.89E-08 2.15E-09 2.08E-08 152 671 "ASIC1,ADCY5,ADCY8,FZD9,ADORA1,ADORA2A,ADRA1B,ADRB2,AGT,UNC79,AMPH,APBA2,DDO,SPTBN4,ARRB2,PDE8B,NCOA1,ATP1A3,ATP2B2,ADGRB3,BBS2,BCHE,SYNJ1,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,CCK,USP2,DGKI,NOG,CHRNA4,NRXN3,CLCN3,CNR1,CNTFR,ZNF385A,CRHBP,CSNK1E,CNTNAP2,SLITRK5,PUM1,BRINP1,DBI,GIT2,DBN1,LYPD1,DNM1,SHANK1,RCAN1,SEZ6L2,EGFR,EIF4G1,RCAN2,ETV1,PPP1R1B,FGF12,FGF13,FGF14,AFF2,FYN,GAA,CHL1,GABRG2,GAD1,PCDH17,HPGDS,GNAO1,MCHR1,GPR37,GRIN2D,HMGCR,NEGR1,IGF1,LRRTM1,KCND2,KIT,LSAMP,MAPT,SHC3,MEF2C,MEIS1,MEIS2,MMP17,ADAM22,MYO5A,MYO6,NF1,NPY,NOVA1,NPTX2,SLC11A2,NTRK2,OPRL1,OXTR,P2RY1,PDE1B,SLC10A4,TMOD2,ZDHHC8,NLGN3,PPARA,PRKAR1B,MAPK10,RELN,PTN,OXR1,RASGRF1,FIGN,MRAP2,LRRK2,KCNIP3,RMI1,S100B,SCN8A,SGK1,CPEB3,NLGN1,PREX2,SNAP25,SNCA,MBD5,ANKFN1,VPS13A,DNAJC9,PLCB1,ARC,TACR1,TAL1,ADGRL3,AGTPBP1,CUX2,CRTC1,THRA,BHLHB9,NR2E1,RASD2,NR2C2,TSC1,UCHL1,VLDLR,LGI4,ZIC1,NDRG4,SLC17A7,KCNAB1,EPM2A,AAAS,IFT88,NETO1,JPH3" GO: Biological Process GO:0031344 regulation of cell projection organization 1.15E-11 1.02E-07 3.09E-09 2.99E-08 149 657 "ACHE,ADCY6,TBC1D14,SEMA6A,SEMA7A,APC,CPNE5,SEMA4G,ARHGDIA,NUMB,ADGRB3,BMP7,ARHGEF7,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,ARHGEF1,CBFA2T2,SEPT7,CDH2,EVI5L,NUMBL,CHN1,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CCDC151,CNR1,CNTN1,AKAP5,CRMP1,AATK,SIPA1L1,PLXNA4,PPP1R16B,RIMS2,USP6NL,ARHGAP24,HDAC4,TBC1D5,IST1,DBN1,KIAA0319,DMD,SHANK1,DPYSL2,WDPCP,SEMA3D,PLXNC1,EIF4G2,TENM1,CDKL3,SH3YL1,TBC1D16,PTK2B,FER,OLFM1,FGF13,FGFR1,BAIAP2,EVL,SEMA4D,SYT3,PDLIM5,STAU2,FYN,SYT17,DISC1,SEPT9,STMN2,CIT,LINGO1,NEGR1,RBPJ,KNDC1,ITPKA,KIT,L1CAM,MAP2,MAP4,MAPT,MBP,MEF2C,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,P2RX7,PALM,PAX6,ENPP2,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,RELN,KLK6,BCAS3,PTK2,PTN,PTPRD,PTPRG,PTPRO,CEP97,RDX,RET,KCTD17,ROBO1,ROBO2,LRRK2,SEMA6D,SGK1,CPEB3,FUZ,NLGN1,CCDC88A,TRIM67,SNAP25,SPP1,SPART,CLASP2,TTBK2,KANK1,SYT1,COBL,CUX2,SYNE1,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,NR2E1,GORASP1,VLDLR,TBC1D15,WNT7A,NDRG4,EVI5,SEMA3B,ITM2C,RTN4,IFT88" GO: Biological Process GO:0099531 presynaptic process involved in chemical synaptic transmission 1.83E-11 1.62E-07 4.75E-09 4.59E-08 57 173 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,DGKI,NRXN3,SNCAIP,RIMS4,RIMS2,SNPH,SNAP91,EDN3,STX2,SYT3,BRSK1,GAD1,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,ICA1,C2CD4C,SYTL4,MEF2C,NF1,NTRK2,P2RX7,PTPRN2,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0051345 positive regulation of hydrolase activity 2.38E-11 2.10E-07 6.01E-09 5.80E-08 194 929 "RALGAPA1,ABR,AXIN2,ADRB2,AGT,TBC1D14,ARHGAP20,AMPH,BIN1,FGD2,C6orf89,PKP4,APAF1,APOC2,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,BID,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,ARHGEF25,CCK,RGN,ARHGEF1,ARHGEF2,ARHGAP33,EVI5L,RCBTB2,CHN1,CHN2,ARHGAP22,NGEF,ARHGEF6,AKAP6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,DAPK1,GIT2,ELMO1,TIAM2,SGSM2,DOCK2,CASP8AP2,DNAJB6,FIS1,EDNRA,RASGRP1,FAM13A,EGFR,RASA4,EIF5,RGS17,PCOLCE2,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GNAO1,ADAP1,GPER1,GRIN2C,GRIN2D,GSN,NCKAP1L,ARHGAP36,GABARAPL2,AGFG1,SMAP1,IFI16,KNDC1,INPP5B,JAK2,KIT,STXBP5,LIMS1,SHC3,MEF2C,KITLG,AFDN,GIT1,MYO9A,NF1,SLC11A2,NTRK3,TBC1D25,OCRL,PDCD2,PDPK1,PLCB2,PLXNB1,RASGEF1B,MAPK9,PSD,BCAS3,PTK2,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS12,RIC8B,ROBO1,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,RASA3,ASAP3,PREX2,ARHGEF40,ARFGAP1,SNCA,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,DNAJC9,PLCB1,MTCL1,MCF2L,DNMBP,TCEA1,DOCK9,ARHGAP9,TEK,SIRT1,TIAM1,TPM1,TRIO,TSC1,TSC2,BCL2L13,MTCH1,VAV1,TBC1D15,LMF1,P2RY12,WRN,EVI5,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:0007420 brain development 3.93E-11 3.47E-07 9.65E-09 9.33E-08 164 755 "ABR,NDRG2,PCDH19,NME5,AK2,OGT,SEMA7A,APAF1,APLP1,SHROOM2,ARRB2,CHRD,NCOA1,NUMB,DYNLL1,ATP2B2,BBS2,NRP2,BID,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,SYNGR3,CDH2,DCLK1,NOG,NUMBL,SLIT2,LHX2,VAX2,CNTN1,WHRN,AKAP5,NCOR1,NCOR2,AATK,CSF1R,CNTNAP2,PLXNA4,SLITRK5,SNPH,DBI,SEC16A,DLX1,CDON,DPYSL2,SEZ6L2,EGFR,EMX2,ERBB4,EZH1,DLC1,SEC24B,FGF13,FGFR1,FGFR3,FOXO3,AFF2,AK8,FYN,DISC1,PPARGC1A,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,PADI2,HNMT,IGF1,ZIC5,RBPJ,KNDC1,SLC6A17,KCNK3,STMN1,SMAD1,SMAD9,MAPT,MBP,AFDN,NEFH,NF1,NFIX,NNAT,NPY,NTRK2,OXTR,PAX6,PCDH9,PFKFB3,PCDH18,MAPKAP1,SEPT4,MBOAT7,POU6F1,PPP3CC,HYDIN,RELN,PTCH1,PTN,FAT4,ROGDI,CRTAC1,ROBO1,ROBO2,RORB,LRRK2,ATAT1,SALL1,SEMA6D,ATXN2,KIF27,TRA2B,ARX,BTBD3,ZNF430,SLC6A11,SLC8A1,SIRT2,CDK5RAP3,SMARCA4,SMARCC2,CDK5RAP2,FAIM2,MYO16,SOX3,SSTR1,SSTR2,TTBK2,PLCB1,SYT1,TACC1,AGTPBP1,SATB2,RPGRIP1L,SZT2,DICER1,CDH22,THRA,NR2E1,NR2C2,TSC1,UBE3A,CCDC14,VLDLR,WNT7A,WRN,ZIC1,ZIC2,NDRG4,SPHK2,GDPD5,PRDM8,SLC17A7,KCNAB1,FZD3,RTN4,IFT88" GO: Biological Process GO:0001505 regulation of neurotransmitter levels 4.13E-11 3.64E-07 9.85E-09 9.52E-08 65 214 "SYN3,ASIC1,ACHE,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,DGKI,NRXN3,SNCAIP,RIMS4,RIMS2,SNPH,SNAP91,EDN3,STX2,SYT3,BRSK1,GAD1,SYT17,CPLX2,CPLX1,GLUL,KCNMB4,GPER1,PCLO,GRIK5,GRM8,HNMT,ICA1,C2CD4C,SYTL4,MEF2C,NF1,NTRK2,P2RX7,PDE1B,PTPRN2,PRIMA1,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,AGTPBP1,WNT7A,TRIM9,SLC38A1,SLC17A7" GO: Biological Process GO:0010975 regulation of neuron projection development 4.36E-11 3.85E-07 1.01E-08 9.80E-08 118 492 "ACHE,ADCY6,SEMA6A,SEMA7A,CPNE5,SEMA4G,ARHGDIA,NUMB,ADGRB3,BMP7,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,ARHGEF1,CBFA2T2,CDH2,NUMBL,CHN1,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,SIPA1L1,PLXNA4,RIMS2,IST1,DBN1,KIAA0319,DMD,SHANK1,DPYSL2,SEMA3D,PLXNC1,EIF4G2,CDKL3,PTK2B,OLFM1,FGF13,FGFR1,BAIAP2,SEMA4D,SYT3,PDLIM5,STAU2,FYN,SYT17,DISC1,STMN2,CIT,LINGO1,NEGR1,RBPJ,KNDC1,ITPKA,L1CAM,MAP2,MAPT,MBP,MEF2C,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,NLGN3,SEMA5B,PLXNB1,PMP22,PPP3CA,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,RET,ROBO1,ROBO2,LRRK2,SEMA6D,SGK1,CPEB3,NLGN1,CCDC88A,TRIM67,SNAP25,SPP1,SPART,CLASP2,KANK1,SYT1,COBL,CUX2,SYNE1,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,NR2E1,GORASP1,VLDLR,WNT7A,NDRG4,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0060322 head development 7.09E-11 6.26E-07 1.61E-08 1.55E-07 171 802 "ABR,NDRG2,PCDH19,NME5,AK2,OGT,SEMA7A,APAF1,APLP1,SHROOM2,ARRB2,CHRD,NCOA1,NUMB,DYNLL1,ATP2B2,BBS2,NRP2,BID,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,SYNGR3,CDH2,DCLK1,NOG,NUMBL,SLIT2,LHX2,VAX2,CNTN1,WHRN,AKAP5,NCOR1,NCOR2,AATK,CSF1R,CNTNAP2,PLXNA4,SLITRK5,SNPH,DBI,SEC16A,DLX1,CDON,DPYSL2,SEZ6L2,EDNRA,EGFR,PLEKHA1,EMX2,ERBB4,EZH1,DLC1,SEC24B,FGF13,FGFR1,FGFR3,FOXO3,AFF2,AK8,FYN,DISC1,PPARGC1A,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,PADI2,HNMT,IGF1,ZIC5,RBPJ,KNDC1,SLC6A17,KCNK3,STMN1,SMAD1,SMAD9,MAPT,MBP,AFDN,MYH3,NEFH,NF1,NFIX,NNAT,NPY,NTRK2,OXTR,PAX6,PCDH9,PFKFB3,PCDH18,MAPKAP1,SCHIP1,SEPT4,MBOAT7,POU6F1,PPP3CC,MAPK3,HYDIN,RELN,PTCH1,PTN,FAT4,ROGDI,CRTAC1,ROBO1,ROBO2,RORB,LRRK2,ATAT1,SALL1,SEMA6D,ATXN2,KIF27,TRA2B,ARX,BTBD3,ZNF430,SLC6A11,SLC8A1,SIRT2,CDK5RAP3,SMARCA4,SMARCC2,CDK5RAP2,FAIM2,MYO16,SOX3,SSTR1,SSTR2,TTBK2,PLCB1,SYT1,TACC1,AGTPBP1,SATB2,RPGRIP1L,SZT2,DICER1,CDH22,THRA,NR2E1,NR2C2,TSC1,UBE3A,CCDC14,VLDLR,WNT7A,WRN,ZIC1,ZIC2,NDRG4,SPHK2,ZFAND5,GDPD5,PRDM8,SLC17A7,KCNAB1,FZD3,RTN4,KAT6A,IFT88" GO: Biological Process GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 7.38E-11 6.52E-07 1.63E-08 1.58E-07 53 160 "PCDH19,PCDH10,PCDHGB4,CDH2,NECTIN3,CELSR3,CHL1,PCDH17,PTPRT,CDH20,L1CAM,PCDHGC3,PCDH8,PCDH9,PKD1,PCDH18,SDK2,DCHS2,PTPRG,FAT4,RET,ROBO1,ROBO2,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TRO,PCDH20,CADM2" GO: Biological Process GO:0006836 neurotransmitter transport 7.76E-11 6.85E-07 1.67E-08 1.62E-07 64 212 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,DGKI,NRXN3,SNCAIP,RIMS4,RIMS2,SNPH,SNAP91,SV2B,EDN3,STX2,SYT3,BRSK1,GAD1,SYT17,CPLX2,CPLX1,GLUL,KCNMB4,GPER1,PCLO,GRIK5,GRM8,ICA1,SLC6A17,C2CD4C,SYTL4,MEF2C,NF1,NTRK2,P2RX7,PTPRN2,LRRK2,STX1B,NLGN1,SLC6A8,SLC6A11,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,WNT7A,TRIM9,SLC38A1,SLC17A7" GO: Biological Process GO:0050803 regulation of synapse structure or activity 2.23E-10 1.97E-06 4.69E-08 4.54E-07 75 272 "ABHD6,ADORA1,ADORA2A,AGT,PPFIA3,ATP2B2,ADGRB1,ADGRB2,ADGRB3,CALB1,CAMK2A,CAMK2B,CBLN1,CD38,DGKI,CDH2,NRXN3,PICK1,SIPA1L1,SLITRK5,DBI,DBN1,DMPK,EPHB1,PTK2B,FGF14,BAIAP2,PDLIM5,STAU2,DISC1,CPLX2,PCDH17,SHISA6,MYLK2,LRRTM1,ITPKA,KCNB1,KIT,MAPT,MEF2C,MYO6,NF1,NTRK2,NTRK3,OXTR,NLGN3,LRRN3,RELN,PTK2,PTN,RASGRF1,RASGRF2,ROBO2,S100B,CPEB3,NLGN1,SNAP25,SNCA,IQSEC2,CLSTN2,STAU1,STXBP1,ARC,SYP,ADGRL3,CUX2,CRTC1,BHLHB9,NR2E1,LRRC24,FLRT2,VGF,WNT7A,NETO1,JPH3" GO: Biological Process GO:0048813 dendrite morphogenesis 2.61E-10 2.31E-06 5.37E-08 5.19E-07 48 142 "ACHE,NUMB,ADGRB3,CACNA1A,KALRN,CAMK2A,CAMK2B,SEPT7,DCLK1,NUMBL,NGEF,AKAP5,SIPA1L1,SLITRK5,DBN1,SHANK1,EPHB1,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,FYN,CIT,KNDC1,ITPKA,MAP2,MAP6,SLC11A2,NLGN3,PPP3CA,RELN,PTPRD,ROBO1,LRRK2,SGK1,NLGN1,PREX2,BTBD3,CUX2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,GORASP1,VLDLR,WNT7A" GO: Biological Process GO:0010769 regulation of cell morphogenesis involved in differentiation 3.11E-10 2.75E-06 6.24E-08 6.03E-07 94 374 "ACHE,AXIN2,SEMA6A,SEMA7A,EPB41L5,SEMA4G,ARHGDIA,NUMB,ADGRB3,ARHGEF7,LDLRAD4,CACNA1A,KALRN,CAMK2B,ARHGEF1,CDH2,NUMBL,CHN1,SLIT2,NGEF,AKAP5,AATK,SIPA1L1,PLXNA4,MYADM,IST1,DBN1,DPYSL2,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,FGF13,BAIAP2,MAD2L2,SEMA4D,PDLIM5,STAU2,DISC1,GCNT2,CIT,LINGO1,HAS2,KNDC1,ITPKA,L1CAM,LIMS1,MAP2,MAPT,MBP,NRCAM,NTRK2,NTRK3,ENPP2,NLGN3,SEMA5B,PLXNB1,PPP3CA,MAPK9,RELN,PTK2,PTPRD,PTPRO,RET,ROBO1,ROBO2,LRRK2,AP1AR,SALL1,SEMA6D,SGK1,FUZ,ST6GAL1,NLGN1,SPP1,SPART,PBLD,CLASP2,PHLDB1,KANK1,CUX2,CLASP1,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,TTC3,GORASP1,WNT7A,CRB2,SEMA3B,RTN4" GO: Biological Process GO:0051962 positive regulation of nervous system development 3.77E-10 3.33E-06 7.41E-08 7.16E-07 122 531 "ACHE,BEND6,SEMA6A,BIN1,SEMA7A,CPNE5,ARHGDIA,ASPA,NCOA1,NUMB,ADGRB1,ADGRB2,ADGRB3,BMP7,SYNJ1,MYRF,KALRN,HAP1,CAMK2B,SPAG9,CBLN1,CBFA2T2,NOG,NUMBL,SLIT2,CPNE6,NRXN3,QKI,CNR1,CNTN1,AKAP5,CSF1,RGS6,SLITRK5,RIMS2,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,HEYL,EIF4G1,EIF4G2,EPHB1,CDKL3,PTK2B,PRMT5,FGFR1,BAIAP2,SEMA4D,SYT3,DLL3,STAU2,FYN,SYT17,DISC1,GLI2,GPER1,STMN2,NEGR1,IGF1,IL6ST,LRRTM1,ITPKA,KIT,L1CAM,LIG4,MAPT,MEF2C,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,PALM,PAX6,ENPP2,NLGN3,PLXNB1,LRRN3,RELN,PTK2,PTN,PTPRD,RET,ROBO1,ROBO2,SALL1,SGK1,CPEB3,NLGN1,TRIM67,SMARCD3,SOX11,KDM4C,CLSTN2,SYT1,COBL,ADGRL3,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,BHLHB9,PARD3,LRRC24,FLRT2,VLDLR,WNT7A,XRCC4,NDRG4,GDPD5,FZD3,RTN4" GO: Biological Process GO:0051049 regulation of transport 1.27E-09 1.12E-05 2.44E-07 2.36E-06 350 1975 "KCNH8,ABR,ASIC1,ACHE,ADCY5,ADD1,AXIN2,ADORA1,ADORA2A,ADRB2,AGT,TBC1D14,OSBPL8,C1QTNF1,C1QTNF3,SYT13,DOC2A,BIN1,OGT,DPP10,ANK2,KCNAB2,APOC1,APOC2,MADD,CASK,SPTBN4,ARNTL,ARRB1,RGS20,ARRB2,CADPS,PDE8B,DYNLL1,ATP1A1,ATP1B3,ATP2A2,ATP2B2,RIPK1,BARD1,HCN2,BID,BMP7,SYNJ1,ARHGEF7,MTMR2,CACNA1I,CACNA1G,C5,RAB29,IL33,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2G,CAPN3,CCK,USP6,RGN,SCARB1,SYNGR3,CD38,CDH2,KCNAB3,EVI5L,CACNA2D2,CBARP,CHRNA4,CLCN3,STOML1,MAP4K4,RAB26,CNR1,PICK1,CNTN1,AKAP7,AKAP6,CABP1,AKAP5,BAG4,MYRIP,CLOCK,CRHBP,CRY2,NCOR1,CLIP3,ABCG1,SNCAIP,CSF1R,RIMS4,APPL1,RIMS2,RUBCN,USP6NL,CYBB,GAPVD1,TCAF1,SNPH,ZFYVE16,TBC1D5,DAPK1,DBI,DBN1,B3GAT3,C2CD2L,POM121,SNAP91,SGSM2,DMD,DNM1,DMPK,SHANK1,DOCK2,DPP6,DPYSL2,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,EGFR,TENM1,TNK2,ERBB2,ERBB4,APC2,DNAJC27,TLR7,SIRPB1,REEP2,TBC1D16,ACSL4,PTK2B,PRAM1,RACK1,FCGR1A,SEC24B,FER,FGF12,FGF14,FGFR1,PRKAG2,FHL1,MEX3B,ANKFY1,SYT3,ZBED3,HVCN1,TRIM16,PRELID3A,SARAF,OGA,GABBR1,SYT17,INPP5K,CPLX2,CPLX1,GCK,ARFIP1,GDF9,PCDH17,PPARGC1A,GLUL,KCNMB4,GNAO1,STON1,MCHR1,GPER1,PCLO,GRB10,GRIK5,GRIN2D,GRM8,BVES,PACSIN2,NCKAP1L,HMGCR,HNMT,HSPA1L,SMAP1,ICA1,MYLK2,IGF1,SCIN,LRRTM1,C2CD4C,JAK2,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNN2,KCNN3,KCNQ3,IPO5,STXBP5,SYTL4,MAPT,LYPLAL1,MEF2C,SCAMP5,MXI1,MYO5A,MYO6,MYT1,FXYD7,HNRNPM,NEFH,NELL2,NF1,NFE2L2,NNAT,NTRK2,NUCB2,TBC1D25,OGG1,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PDE1C,PDE4B,PDE4D,PDPK1,PFKFB2,ZDHHC8,NLGN3,NALCN,PIK3C2A,PIK3R1,PKD1,PLCD1,FXYD1,PLTP,PPARA,PPM1B,PPP3CA,PPP3CC,NKAIN4,RANBP3L,PKIA,PRKCB,MAPK3,MAPK7,MAPK9,RELN,BCAS3,PTCH1,PTK2,PTX3,NKAIN1,PID1,SH3TC2,RASGRF1,RASGRF2,RDX,RFX3,RNASEL,FBXW7,SGSM1,LRRK2,KCNIP3,KCNIP1,STX1B,ATXN2,SCN2B,SCN7A,SCN8A,SCP2,SMPD3,SGK1,MYO18A,SYBU,NLGN1,ABLIM3,EPN2,SLC8A1,SLC11A1,NAPB,LGI3,ARFGAP1,SNAP25,SNCA,LMBRD1,SOX11,PBLD,CLASP2,NKAIN2,STX1A,KANK1,SULF2,STXBP1,PLCB1,SYN1,ARC,SYT1,SYT5,TACR1,MTCL1,FBXW11,TPCN2,CLASP1,SYNE1,TEK,SIRT1,THRA,TIAM1,TLR4,LRRC8A,PARD3,TP53BP2,STXBP4,TRPM2,KCNE5,TSC2,SGK3,TBC1D15,VSNL1,WIPF1,P2RY12,KCNK12,XPO1,ZIC1,TRIM9,NDRG4,REEP1,SLC30A3,MFF,EVI5,HPS4,KCNAB1,WNK3,WNK2,RTN4,NLRP3,AAAS,NETO2,JPH3" GO: Biological Process GO:0050808 synapse organization 1.88E-09 1.66E-05 3.53E-07 3.41E-06 70 258 "ACHE,ATP2B2,ADGRB1,ADGRB2,ADGRB3,CACNA1A,CACNB4,CAMK2B,CBLN1,CDH2,CACNA2D2,NRXN3,COL4A5,SLITRK5,SPOCK2,DBN1,RAB39B,DMPK,SHANK1,DRP2,SEZ6L2,EPHB1,GPHN,ERBB2,ERBB4,PDLIM5,STAU2,DISC1,PCDH17,PCLO,LRRTM1,MEF2C,DBNL,MYO5A,MYO6,NRCAM,NTRK2,NTRK3,OXTR,PALM,PCDHGC3,NLGN3,SDK2,LRRN3,RELN,PTK2,PTN,PTPRD,ROBO2,LRRK2,NLGN1,SNCA,PDZRN3,NFASC,CLSTN2,ZC4H2,ADGRL3,CUX2,PCDHGC5,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,BHLHB9,LRRC24,TSC1,FLRT2,WNT7A,ELFN1" GO: Biological Process GO:0048167 regulation of synaptic plasticity 6.42E-09 5.67E-05 1.18E-06 1.14E-05 51 169 "ABHD6,ADORA1,ADORA2A,AGT,PPFIA3,ATP2B2,CALB1,CAMK2A,CAMK2B,CD38,DGKI,PICK1,SIPA1L1,DBI,DBN1,PTK2B,FGF14,BAIAP2,STAU2,CPLX2,SHISA6,MYLK2,LRRTM1,ITPKA,KCNB1,KIT,MAPT,MEF2C,MYO6,NF1,NTRK2,NLGN3,RELN,PTN,RASGRF1,RASGRF2,S100B,CPEB3,NLGN1,SNAP25,SNCA,IQSEC2,STAU1,STXBP1,ARC,SYP,CRTC1,NR2E1,VGF,NETO1,JPH3" GO: Biological Process GO:0060079 excitatory postsynaptic potential 6.90E-09 6.10E-05 1.24E-06 1.20E-05 28 67 "ADORA1,ADORA2A,ADRB2,MTMR2,DGKI,RIMS2,DBN1,DMPK,SHANK1,PTK2B,GRIK5,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,RELN,LRRK2,STX1B,NLGN1,SNCA,STX1A,CUX2,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0023061 signal release 7.14E-09 6.31E-05 1.26E-06 1.22E-05 112 498 "SYN3,ASIC1,ADCY5,ADORA1,ADORA2A,AGT,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,PPFIA4,PPFIA3,MADD,CASK,ARNTL,ARRB1,CADPS,PDE8B,ATP2A2,SYNJ1,ARHGEF7,BTK,BAIAP3,CACNA1A,CACNA1B,CAMK2A,CAMK2G,CD38,DGKI,CACNA2D2,NRXN3,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,CRY2,SNCAIP,RIMS4,RIMS2,SNPH,C2CD2L,SNAP91,EDN1,EDN3,EGFR,STX2,FGFR1,SYT3,BRSK1,OGA,GABBR1,GAD1,SYT17,CPLX2,CPLX1,GCK,GDF9,GLUL,KCNMB4,GPER1,PCLO,GRIK5,GRM8,HMGCR,ICA1,C2CD4C,JAK2,KCNB1,SYTL4,MEF2C,MYO5A,MYT1,NELL2,NF1,NNAT,NTRK2,NUCB2,P2RX7,P2RY1,PAX6,PDE1C,PFKFB2,PPP3CA,PTPRN,PTPRN2,RFX3,LRRK2,STX1B,SMPD3,SYBU,NLGN1,NAPB,SNAP25,SNCA,SOX11,STX1A,STXBP1,SYN1,SYN2,SYT1,SYT5,TACR1,SIRT1,TIAM1,STXBP4,TRPM2,VGF,VSNL1,WNT7A,TRIM9" GO: Biological Process GO:0022603 regulation of anatomical structure morphogenesis 9.22E-09 8.14E-05 1.60E-06 1.54E-05 215 1128 "ABR,ACHE,FMNL2,ADD1,AXIN2,ADRB2,AP2A1,AP2A2,AGT,TBC1D14,SEMA6A,SEMA7A,FGD2,APC,EPB41L5,GAS7,CPNE5,SEMA4G,ARHGDIA,ARRB2,NUMB,ADGRB1,ADGRB2,ADGRB3,CFLAR,BMP7,ARHGEF7,C5,LDLRAD4,CFAP410,CACNA1A,KALRN,HAP1,CAMK2B,KRIT1,ARHGEF1,SEPT7,CDH2,ZMYM4,EVI5L,NOG,NUMBL,CHN1,TAOK2,SLIT2,CPNE6,CLTC,NGEF,CCDC151,AKAP5,MAGED1,AATK,CSF1,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,CST3,PLXNA4,PPP1R16B,RIMS2,USP6NL,CYBB,HDAC9,MYADM,TBC1D5,IST1,DAPK3,DBN1,PARD6A,MED12,DPYSL2,DNM1L,FIS1,WDPCP,EDN1,EDNRA,SEMA3D,CELSR3,PLXNC1,EIF4G2,EPB41,EPB41L2,ERBB2,CDKL3,EYA1,TBC1D16,PTK2B,DLC1,RACK1,SEC24B,FGF1,OLFM1,FGF13,FGFR1,BAIAP2,MAD2L2,SEMA4D,FLT1,SYT3,PDLIM5,STAU2,FYN,ERAP1,SYT17,DISC1,SEPT9,GCNT2,PPARGC1A,TTBK1,FERMT2,CIT,GSN,BVES,LINGO1,HAS2,NKD1,RBPJ,KNDC1,ITGA7,ITPKA,KIT,L1CAM,LIMS1,MAP2,MAP4,MAPT,MBP,MEF2C,MKLN1,NACA,NF1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,ENPP2,NLGN3,SEMA5B,PLXNB1,SH3KBP1,PPP3CA,PRKCB,MAPK7,MAPK9,FITM2,RELN,PSMA6,QRICH1,PTK2,PTN,PTPRD,PTPRO,PID1,CEP97,RDX,RET,KCTD17,RNH1,ROBO1,ROBO2,FBXW7,LRRK2,RXRA,AP1AR,S100B,SALL1,SEMA6D,SGK1,FUZ,ST6GAL1,NLGN1,ANKRD6,LIMS2,BTBD7,SPP1,SPART,PBLD,CLASP2,MESP1,LARP4,TTBK2,PHLDB1,KANK1,SULF2,ARC,SYT1,TCF4,CUX2,CLASP1,SYNE1,OBSL1,TEK,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,TPM1,TTC3,UBC,GORASP1,TBC1D15,WIPF1,WNT7A,CRB2,MFF,EVI5,SEMA3B,FZD3,RTN4,IFT88" GO: Biological Process GO:0051056 regulation of small GTPase mediated signal transduction 1.13E-08 9.94E-05 1.91E-06 1.85E-05 75 295 "RALGAPA1,ABR,ADRA1B,ARHGAP20,OGT,CDC42BPA,FGD2,MADD,ARHGDIA,ARHGDIG,ARRB1,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,DGKI,ARHGEF2,CDH2,ARHGAP33,CHN1,CHN2,ARHGAP22,SLIT2,NGEF,ARHGEF6,CSF1,ARHGEF10,SIPA1L1,ARHGEF4,ARHGAP32,ARHGAP24,TIAM2,RHOBTB1,CDON,DOCK2,RASGRP1,FAM13A,RASA4,ERBB2,DLC1,PSD2,STAMBP,ARHGAP36,IGF1,INPP5B,ITPKB,KITLG,MYO9A,NF1,OCRL,MAPKAP1,RELN,PSD,IQSEC3,RASGRF1,RASGRF2,RDX,ROBO1,RASA3,PREX2,ARHGEF40,TRIM67,ARHGAP26,IQSEC2,MCF2L2,KANK1,ARHGEF9,MCF2L,DNMBP,ARHGAP9,TIAM1,TRIO,TSC2,VAV1,SPATA13" GO: Biological Process GO:0048814 regulation of dendrite morphogenesis 1.19E-08 1.05E-04 1.98E-06 1.92E-05 33 89 "ACHE,NUMB,ADGRB3,KALRN,CAMK2B,NUMBL,NGEF,AKAP5,SIPA1L1,DBN1,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,CIT,KNDC1,ITPKA,NLGN3,PPP3CA,RELN,PTPRD,ROBO1,LRRK2,SGK1,NLGN1,CUX2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,GORASP1" GO: Biological Process GO:0016358 dendrite development 1.59E-08 1.41E-04 2.60E-06 2.51E-05 64 239 "ACHE,NUMB,ADGRB3,BMP7,CACNA1A,KALRN,CAMK2A,CAMK2B,SEPT7,DCLK1,NUMBL,NGEF,AKAP5,SIPA1L1,SLITRK5,DBN1,KIAA0319,GRIN3A,SHANK1,EIF4G2,EPHB1,CDKL3,ACSL4,BAIAP2,SEMA4D,PDLIM5,STAU2,FYN,DISC1,CIT,KNDC1,ITPKA,MAP2,MAP6,MATN2,MEF2C,GIT1,MYO6,SLC11A2,NTRK2,OPA1,PALM,NLGN3,PPP3CA,RELN,PTPRD,ROBO1,LRRK2,SGK1,CPEB3,NLGN1,PREX2,BTBD3,COBL,CUX2,SYNE1,OBSL1,CRTC1,TIAM1,BHLHB9,NR2E1,GORASP1,VLDLR,WNT7A" GO: Biological Process GO:0099504 synaptic vesicle cycle 1.62E-08 1.43E-04 2.60E-06 2.51E-05 40 121 "SYT13,DOC2A,AMPH,CADPS,ATP2A2,SYNJ1,CACNA1A,CDH2,CLCN3,RIMS4,RIMS2,SNPH,DNM1,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIK5,C2CD4C,SYTL4,P2RX7,NLGN3,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYT1,SYT5,WNT7A,TRIM9,SLC17A7" GO: Biological Process GO:0007626 locomotory behavior 1.65E-08 1.46E-04 2.60E-06 2.51E-05 63 234 "ADCY5,ADORA2A,ADRA1B,APBA2,SPTBN4,ARRB2,ATP1A3,ATP2B2,CACNA1A,CACNA1B,CACNB4,CALB1,USP2,CHRNA4,CLCN3,ZNF385A,PUM1,DBN1,DNM1,RCAN1,SEZ6L2,RCAN2,FGF12,FGF14,GAA,CHL1,GAD1,HPGDS,GNAO1,GPR37,GRIN2D,NEGR1,LRRTM1,KCND2,LSAMP,MAPT,MEIS1,ADAM22,MYO5A,MYO6,NOVA1,OPRL1,PDE1B,ZDHHC8,MAPK10,RELN,OXR1,FIGN,LRRK2,SCN8A,PREX2,SNAP25,SNCA,ANKFN1,VPS13A,TAL1,ADGRL3,AGTPBP1,RASD2,TSC1,UCHL1,LGI4,ZIC1" GO: Biological Process GO:0050773 regulation of dendrite development 2.01E-08 1.78E-04 3.09E-06 2.99E-05 46 150 "ACHE,NUMB,ADGRB3,BMP7,KALRN,CAMK2B,NUMBL,NGEF,AKAP5,SIPA1L1,DBN1,KIAA0319,SHANK1,EIF4G2,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,DISC1,CIT,KNDC1,ITPKA,MEF2C,NTRK2,OPA1,PALM,NLGN3,PPP3CA,RELN,PTPRD,ROBO1,LRRK2,SGK1,CPEB3,NLGN1,COBL,CUX2,SYNE1,OBSL1,CRTC1,TIAM1,BHLHB9,NR2E1,GORASP1,VLDLR" GO: Biological Process GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 2.03E-08 1.79E-04 3.09E-06 2.99E-05 62 230 "PCDH19,ALCAM,PCDH10,PCDHGB4,CBLN1,CLDN10,CDH2,NECTIN3,MYADM,CELSR3,ATP2C1,CHL1,PCDH17,PTPRT,CDH20,L1CAM,CLDN11,PCDHGC3,PCDH8,PCDH9,PKD1,PCDH18,SDK2,MAPK7,DCHS2,PTPRD,PTPRG,FAT4,RET,ROBO1,ROBO2,NLGN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TRO,PCDH20,CADM2" GO: Biological Process GO:0060078 regulation of postsynaptic membrane potential 2.44E-08 2.16E-04 3.66E-06 3.54E-05 35 100 "ADORA1,ADORA2A,ADRB2,HCN2,MTMR2,DGKI,CHRNA4,RIMS2,DBN1,DMPK,SHANK1,PTK2B,FGF14,GABRB3,GRIK5,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,RELN,LRRK2,STX1B,SCN2B,SCN7A,SCN8A,NLGN1,SNCA,STX1A,CUX2,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0051094 positive regulation of developmental process 2.82E-08 2.49E-04 4.15E-06 4.01E-05 243 1323 "ACHE,ADD1,AXIN2,ADRB2,BEND6,AGT,SEMA6A,BIN1,OGT,SEMA7A,APC,EPB41L5,CPNE5,SPTBN4,ARHGDIA,ARNTL,ASPA,PTCH2,NCOA1,NUMB,RIPK1,ADGRB1,ADGRB2,ADGRB3,BBS2,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,BTK,C5,MYRF,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,CBLN1,USP2,CD86,CBFA2T2,SEPT7,CDH2,NOG,NUMBL,CACNA2D2,SLIT2,CPNE6,NRXN3,QKI,CNR1,CNTN1,AKAP6,AKAP5,MAGED1,ZNF385A,CSF1,CSF1R,RGS6,SOCS5,SLITRK5,PPP1R16B,CTH,RIMS2,CYBB,BOC,HDAC9,MYADM,MAML1,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,DNM1L,FIS1,EDN1,EDN3,EDNRA,HEYL,RASGRP1,EGR3,EIF4G1,EIF4G2,EPHB1,ERBB4,CDKL3,PTK2B,RACK1,PRMT5,SLC9B2,FGF1,OLFM1,FGFR1,FGFR3,BAIAP2,SUCO,AGAP2,FOXO3,SEMA4D,FLT1,SYT3,TRIM16,CELF1,DLL3,STAU2,FYN,ERAP1,SYT17,DISC1,SEPT9,GCNT2,GHR,PPARGC1A,GLI2,KDM2B,GPER1,STMN2,ATOH8,IRAK3,HAS2,NCKAP1L,HMGCR,NEGR1,SMAP1,IFI16,IGF1,RBPJ,SCIN,IL6R,IL6ST,IL12A,INSM1,LRRTM1,ITPKA,ITPKB,JAK2,KIT,L1CAM,LIG4,LIMS1,SMAD1,SMAD9,MAPT,MEF2C,KITLG,MSR1,NACA,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,P2RX7,PALM,PAX6,PDCD2,PDE3A,ENPP2,NLGN3,PIK3R1,PLXNB1,LRRN3,PRKCB,MAPK9,RELN,GDPD2,PTCH1,PTK2,PTN,PTPRD,PPP2R3C,RET,RFX3,KCTD17,ROBO1,ROBO2,SALL1,MAPK12,SGK1,ARX,CPEB3,FUZ,NLGN1,SLC8A1,SIRT2,TRIM67,EPC1,SMARCA4,SMARCD3,SOX11,SOX15,ZHX3,KDM4C,LMO3,CLASP2,CLSTN2,MESP1,TTBK2,PHLDB1,PLCB1,SYT1,COBL,TAL1,ADGRL3,TCF4,CUX2,ZEB1,TCF12,CLASP1,OBSL1,CRTC1,TEK,DICER1,SIRT1,ZFPM2,THRA,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,IL34,NR2C2,LRRC24,FLRT2,VLDLR,WNT7A,XRCC4,ZIC2,NDRG4,CRB2,MFF,GDPD5,ADAMTS9,HPS4,FZD3,RTN4,NLRP3" GO: Biological Process GO:0048017 inositol lipid-mediated signaling 3.25E-08 2.87E-04 4.71E-06 4.55E-05 58 212 "AGT,OGT,TNRC6C,SYNJ1,CA8,CD86,NRG2,NCOR1,CSF1R,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,AGAP2,SEMA4D,FLT1,STAMBP,FYN,TNRC6A,GPER1,GSN,TNFAIP8L3,IGF1,JAK2,KIT,PIK3AP1,KITLG,MOV10,NF1,NTRK2,PDPK1,PIK3C2A,PIK3R1,PLXNB1,MAPKAP1,MAPK3,RELN,PTK2,PTPN13,PREX2,SIRT2,MYO16,UNC5B,MLST8,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1,RICTOR" GO: Biological Process GO:0050769 positive regulation of neurogenesis 3.32E-08 2.94E-04 4.74E-06 4.58E-05 104 465 "ACHE,BEND6,SEMA6A,BIN1,SEMA7A,CPNE5,ARHGDIA,ASPA,NCOA1,NUMB,BMP7,SYNJ1,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NOG,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,CSF1,RGS6,RIMS2,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,HEYL,EIF4G1,EIF4G2,CDKL3,PTK2B,PRMT5,FGFR1,BAIAP2,SEMA4D,SYT3,DLL3,STAU2,FYN,SYT17,DISC1,GLI2,GPER1,STMN2,NEGR1,IL6ST,ITPKA,KIT,L1CAM,LIG4,MAPT,MEF2C,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,ENPP2,NLGN3,PLXNB1,RELN,PTK2,PTN,PTPRD,RET,ROBO1,ROBO2,SALL1,SGK1,CPEB3,NLGN1,TRIM67,SMARCD3,SOX11,KDM4C,SYT1,COBL,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,BHLHB9,VLDLR,XRCC4,NDRG4,GDPD5,FZD3,RTN4" GO: Biological Process GO:0050806 positive regulation of synaptic transmission 3.95E-08 3.49E-04 5.54E-06 5.36E-05 46 153 "ADORA1,ADORA2A,ARRB2,SYNJ1,CACNA1B,HAP1,CAMK2B,RIMS2,DBI,DBN1,DNM1,SHANK1,EGFR,ERBB4,PTK2B,GLUL,GPER1,GRIA2,LRRTM1,LAMA2,NF1,NTRK2,OXTR,NLGN3,RELN,PTK2,PTN,RASGRF2,STX1B,S100B,NLGN1,SNAP25,SNCA,IQSEC2,CLSTN2,STAU1,STX1A,ARC,SYT1,TACR1,CUX2,CRTC1,NR2E1,WNT7A,NETO2,NETO1" GO: Biological Process GO:0046928 regulation of neurotransmitter secretion 4.77E-08 4.21E-04 6.52E-06 6.30E-05 26 64 "ASIC1,ADORA2A,ATP2A2,CACNA1A,CACNA1B,CAMK2A,SNCAIP,RIMS4,RIMS2,EDN3,KCNMB4,GPER1,GRIK5,GRM8,ICA1,MEF2C,NF1,NTRK2,LRRK2,STX1B,NLGN1,NAPB,SNCA,STX1A,STXBP1,SYN1" GO: Biological Process GO:0048015 phosphatidylinositol-mediated signaling 4.80E-08 4.24E-04 6.52E-06 6.30E-05 57 209 "AGT,OGT,TNRC6C,SYNJ1,CA8,CD86,NRG2,NCOR1,CSF1R,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,AGAP2,SEMA4D,FLT1,STAMBP,FYN,TNRC6A,GPER1,GSN,IGF1,JAK2,KIT,PIK3AP1,KITLG,MOV10,NF1,NTRK2,PDPK1,PIK3C2A,PIK3R1,PLXNB1,MAPKAP1,MAPK3,RELN,PTK2,PTPN13,PREX2,SIRT2,MYO16,UNC5B,MLST8,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1,RICTOR" GO: Biological Process GO:0007270 neuron-neuron synaptic transmission 4.92E-08 4.35E-04 6.59E-06 6.36E-05 46 154 "SYN3,ADORA1,ADORA2A,ADRB2,ARRB2,CACNA1A,CACNB4,KALRN,HAP1,DGKI,DLGAP2,CLCN3,CNR1,CRHBP,DBI,DNM1,EGFR,ERBB4,PTK2B,GABRB3,GABRG2,GLUL,GRIA2,GRIK5,GRIN2D,GRM2,GRM8,SHC3,MEF2C,NF1,NTRK2,OXTR,TMOD2,NLGN3,PLCL1,RELN,LRRK2,NLGN1,NAPB,SNCA,IQSEC2,STXBP1,SYT1,TACR1,RASD2,SLC17A7" GO: Biological Process GO:0007010 cytoskeleton organization 5.01E-08 4.43E-04 6.61E-06 6.39E-05 217 1164 "ABR,ACTN1,FMNL2,ADD1,ADD2,CC2D2A,TAOK1,SEMA6A,CEP126,CDC42BPA,FGD2,APC,EPB41L5,GAS7,SHROOM2,SPTBN4,ARHGDIA,ARRB1,MARK4,DYNLL1,BBS2,CFLAR,DST,WASF1,CFAP410,LURAP1,CAPN3,PRC1,ARHGEF2,SEPT7,ZMYM4,CFL2,TAOK2,SLIT2,CLTC,CCDC151,CNN3,PICK1,BAG4,CDC42BPB,CRMP1,NCOR1,GDA,CLIP3,CSF1R,ARHGEF10,SIPA1L1,MYADM,KATNAL2,DAPK3,DBN1,ELMO1,KIAA0753,KIF19,SHANK1,DOCK2,DPYSL2,PDCD6IP,DNAJB6,WDPCP,EDN1,FRY,TENM1,EPB41,EPB41L2,APC2,KATNAL1,EYA1,TUBA1B,PTK2B,CORO2B,DLC1,ZMYND10,FER,FGF13,BAIAP2,MAD2L2,AGAP2,EVL,DCTN2,ATP2C1,STAU2,TPPP3,BRSK1,ABLIM2,IQGAP2,DISC1,INPP5K,TUBGCP4,TUBA8,ARFIP1,MAP7D2,DCLK2,PCLO,STMN2,TPPP,CIT,GSN,PACSIN2,NCKAP1L,SYNPO,AGFG1,SMAP1,SCIN,ITPKA,JAK2,KIF2A,KIT,STMN1,MAP2,MAP4,MAP6,MAPT,MARK1,MEF2C,MID1,MKLN1,DBNL,BLOC1S2,MYH3,NEFM,NEFH,CCDC13,NF1,NTRK3,P2RX7,PALM,PAX6,PDPK1,TMOD2,PIK3R1,CCSER2,PKD1,GPSM2,PLXNB1,MAGEL2,EPB41L4B,SH3KBP1,MAPK3,FITM2,HYDIN,PRPH,BCAS3,GDPD2,QRICH1,CNTLN,PTK2,SPDL1,PPP2R3C,CEP97,CCDC40,IQSEC3,RAP1GDS1,RDX,FIGN,KIRREL1,MAP6D1,ATAT1,CLIP1,AP1AR,ATXN7,MRAS,SGK1,PPM1E,ASAP3,MYO18A,FHOD3,NLGN1,ABLIM3,SIRT2,CCDC88A,ELMO2,MAST1,CDK5RAP2,TTC17,LIMCH1,SNCA,USP33,MYCBP2,ARHGAP26,SPTAN1,SPTB,IQSEC2,CLASP2,LARP4,SS18,ERBIN,CEP68,PHLDB1,KANK1,SYNE2,ARC,COBL,TACC1,TACR1,MTCL1,MLST8,CLASP1,SYNE1,OBSL1,FRYL,TEK,DNAH7,DICER1,PARD3,TPM1,TSC1,TUBB1,UGT8,PLEKHH2,WIPF1,RICTOR,XPO1,SPIRE1,ACTR3B,IFT88,GAN" GO: Biological Process GO:0010720 positive regulation of cell development 7.26E-08 6.41E-04 9.36E-06 9.05E-05 121 572 "ACHE,AXIN2,BEND6,SEMA6A,BIN1,SEMA7A,EPB41L5,CPNE5,ARHGDIA,ASPA,NCOA1,NUMB,BMP7,SYNJ1,ARHGEF7,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NOG,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP6,AKAP5,CSF1,RGS6,RIMS2,MYADM,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,EDN1,HEYL,EIF4G1,EIF4G2,CDKL3,PTK2B,PRMT5,SLC9B2,OLFM1,FGFR1,BAIAP2,SEMA4D,SYT3,DLL3,STAU2,FYN,SYT17,DISC1,GCNT2,GLI2,KDM2B,GPER1,STMN2,HAS2,NEGR1,IL6ST,ITPKA,KIT,L1CAM,LIG4,LIMS1,MAPT,MEF2C,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,PDE3A,ENPP2,NLGN3,PLXNB1,MAPK9,RELN,PTK2,PTN,PTPRD,RET,RFX3,ROBO1,ROBO2,SALL1,SGK1,CPEB3,NLGN1,SIRT2,TRIM67,SMARCD3,SOX11,KDM4C,SYT1,COBL,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,BHLHB9,VLDLR,XRCC4,NDRG4,CRB2,GDPD5,FZD3,RTN4" GO: Biological Process GO:0045595 regulation of cell differentiation 7.31E-08 6.46E-04 9.36E-06 9.05E-05 298 1699 "ACHE,ADCY6,AXIN2,BEND6,AP2A2,AGT,SEMA6A,LTBP4,BIN1,OGT,SEMA7A,PI16,APC,EPB41L5,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASPA,PTCH2,CHRD,NCOA1,NUMB,RIPK1,ADGRB3,CFLAR,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,BTK,RAB29,LDLRAD4,CACNA1A,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,RUNX1T1,CD86,ARHGEF1,CBFA2T2,ARHGEF2,CDH2,NOG,NUMBL,CHN1,PLEKHB1,SLIT2,CPNE6,NGEF,FBXO7,QKI,MAP4K4,CNR1,CNTN1,AKAP6,AKAP5,ZNF385A,CLOCK,CRMP1,NCOR2,ABCG1,AATK,CSF1,CSF1R,RGS6,SIPA1L1,SOCS5,PLXNA4,CTH,RIMS2,BOC,HDAC9,MYADM,HDAC4,RASSF2,MAML1,IST1,SPOCK2,BRINP1,DBN1,KIAA0319,DLX1,DMD,DMPK,NR1D2,CDON,SHANK1,DPYSL2,EDN1,EDN3,EDNRB,HEYL,RASGRP1,SEMA3D,EGR3,PLXNC1,EIF4G1,EIF4G2,LRRC17,ERBB2,ERBB4,APC2,CDKL3,ADGRV1,EYA1,PTK2B,PRMT5,SLC9B2,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,SUCO,FOXO3,SEMA4D,FLT1,SYT3,PDLIM5,TRIM16,DLL3,STAU2,FYN,MEGF10,SYT17,DISC1,GCNT2,MSTN,GLI2,KDM2B,LILRB4,GPER1,STMN2,C1QL4,PLPP7,CIT,SOX21,LINGO1,ATOH8,HAS2,NCKAP1L,NEGR1,SMAP1,IFI16,IGF1,RBPJ,KNDC1,SCIN,IL6R,IL6ST,IL12A,INSM1,ITPKA,ITPKB,JAK2,KIT,L1CAM,LIG4,LIMS1,LMO2,SMAD1,SMAD9,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,MEIS2,KITLG,MITF,AFDN,MSR1,MYCN,NACA,NBL1,NF1,NFE2L2,NFYA,NPR2,NRCAM,NTRK2,NTRK3,NUCB2,OPA1,PALM,PAX6,PDCD2,PDE3A,ENPP2,GPR173,NLGN3,SEMA5B,PIK3R1,PLXNB1,PMP22,PPARA,PPP3CA,MAPK9,RELN,KLK6,GDPD2,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PPP2R3C,FAT4,RET,RFX3,ROBO1,ROBO2,RORB,LRRK2,ATAT1,AP1AR,S100B,SALL1,MAPK12,SEMA6D,FNIP1,SGK1,CPEB3,FUZ,ST6GAL1,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,EPC1,SMARCA4,CDK5RAP2,SMARCD3,SNAP25,SOX3,SOX11,KDM3A,ZHX3,SPP1,KDM4C,SPART,LMO3,PBLD,CLASP2,MESP1,PHLDB1,KANK1,PLCB1,SYT1,COBL,TAL1,TCF4,CUX2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,ZFPM2,THRA,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,IL34,NR2C2,TRPS1,TTC3,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,CRB2,GDPD5,ADAMTS9,TMEM178A,SEMA3B,ITM2C,FZD3,RTN4,NLRP3,IFT88" GO: Biological Process GO:0051961 negative regulation of nervous system development 9.01E-08 7.96E-04 1.14E-05 1.10E-04 75 309 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,CHRD,BMP7,MTMR2,RAB29,ARHGEF1,CBFA2T2,ARHGEF2,NOG,SLIT2,NGEF,MAP4K4,CRMP1,AATK,BRINP1,KIAA0319,DLX1,EDNRB,SEMA3D,ERBB4,CDKL3,OLFM1,FGF13,FGFR3,FOXO3,SEMA4D,DLL3,STMN2,CIT,SOX21,LINGO1,RBPJ,MBD1,MBP,MEIS1,MYCN,NF1,NTRK3,PAX6,GPR173,NLGN3,SEMA5B,PMP22,PPP3CA,PRKACB,PTK2,PTN,PTPRG,PTPRO,ROBO2,SEMA6D,NLGN1,SIRT2,CDK5RAP2,IFT122,SOX3,SOX11,SPP1,SPART,KANK1,DICER1,GPR161,HEY1,NR2E1,TTC3,EIF4ENIF1,GORASP1,WNT7A,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0035249 "synaptic transmission, glutamatergic" 1.06E-07 9.32E-04 1.31E-05 1.27E-04 30 83 "ADORA1,ADORA2A,ADRB2,CACNA1A,CACNB4,KALRN,DGKI,CLCN3,CNR1,EGFR,PTK2B,GLUL,GRIA2,GRIK5,GRIN2D,GRM2,GRM8,SHC3,MEF2C,NF1,NTRK2,OXTR,NLGN3,RELN,LRRK2,NLGN1,NAPB,IQSEC2,SYT1,SLC17A7" GO: Biological Process GO:0007411 axon guidance 1.10E-07 9.75E-04 1.36E-05 1.31E-04 62 240 "UNC5A,SEMA6A,ALCAM,SEMA7A,APBB2,SEMA4G,SPTBN4,NRP2,BMP7,BMPR1B,ISPD,NOG,CHN1,SLIT2,LHX2,NRXN3,CRMP1,CSF1R,PLXNA4,BOC,KIF26A,DPYSL2,SEMA3D,CELSR3,PLXNC1,EPHB1,ERBB2,ETV1,TUBB3,EVL,SEMA4D,FYN,CHL1,GLI2,RNF165,KIF5A,L1CAM,LAMA2,MATN2,NRCAM,PAX6,SEMA5B,PLXNB1,MAPK3,RELN,PTK2,PTPRO,ROBO1,ROBO2,SEMA6D,ARX,USP33,MYCBP2,UNC5B,SPTAN1,SPTB,NFASC,FLRT2,ZIC2,DPYSL5,SEMA3B,FZD3" GO: Biological Process GO:0007215 glutamate receptor signaling pathway 1.26E-07 1.12E-03 1.53E-05 1.48E-04 28 75 "ATP1A3,CAMK2A,HOMER3,CRHBP,DAPK1,GRIN3A,SHANK1,PTK2B,PPARGC1A,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNB1,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1,CPEB4,SSTR1,PLCB1,ARC,NETO2" GO: Biological Process GO:0051336 regulation of hydrolase activity 1.29E-07 1.14E-03 1.53E-05 1.48E-04 248 1379 "RALGAPA1,ABR,ELFN2,AXIN2,ADORA2A,ADRB2,AGT,TBC1D14,ARHGAP20,AMPH,BIN1,FGD2,C6orf89,PI16,PKP4,APAF1,APOC1,APOC2,PPP4R4,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,ARRB2,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,BID,CFLAR,ARHGEF7,C5,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,CAST,ARHGEF25,CCK,RGN,ARHGEF1,DGKI,ARHGEF2,ARHGAP33,EVI5L,CCPG1,RCBTB2,CHN1,CHN2,ARHGAP22,SLIT2,NGEF,CNN3,ARHGEF6,AKAP6,BAG4,NRG2,CRY2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,VCAN,CST3,RASGEF1C,ARHGEF4,PPP6R2,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,INTS1,DAPK1,GIT2,DBN1,ELMO1,TIAM2,SPOCK3,SGSM2,CPEB2,DOCK2,CASP8AP2,RCAN1,DNAJB6,FIS1,EDNRA,RASGRP1,FAM13A,EGFR,RASA4,EIF5,TNK2,RGS17,PCOLCE2,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GNAO1,ADAP1,GPER1,GRIN2C,GRIN2D,GSN,BVES,FICD,NCKAP1L,ARHGAP36,GABARAPL2,AGFG1,SMAP1,IFI16,IGF1,KNDC1,INPP5B,JAK2,METTL21A,KIT,IPO5,STXBP5,LIMS1,SHC3,MEF2C,KITLG,AFDN,GIT1,COL28A1,MYO9A,NF1,SLC11A2,NTRK2,NTRK3,TBC1D25,OCRL,PDCD2,PDPK1,SERPINI1,NLE1,PLCB2,PLCD1,PLXNB1,PPP2R2B,PPP2R2C,PPP2R5E,RASGEF1B,MAPK7,MAPK9,PSD,BCAS3,PTK2,PTPRN2,PTX3,USP47,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RDX,RET,RGS3,RGS4,RGS12,RIC8B,ROBO1,SGSM1,LRRK2,MAPK12,SBF1,CSRNP3,FNIP1,RASA3,ASAP3,PREX2,ARHGEF40,CDK5RAP3,ARFGAP1,SNCA,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RBM26,SSPO,ST5,MPRIP,RGL1,ARHGEF9,DNAJC9,PLCB1,MTCL1,MLST8,MCF2L,DNMBP,TCEA1,DOCK9,ARHGAP9,TEK,SIRT1,TIAM1,TIMP4,RIMBP2,TPM1,TPM2,TRIO,TSC1,TSC2,BCL2L13,MTCH1,VAV1,TBC1D15,LMF1,P2RY12,WRN,RICTOR,ELFN1,CRB2,EVI5,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:0097485 neuron projection guidance 1.30E-07 1.15E-03 1.53E-05 1.48E-04 62 241 "UNC5A,SEMA6A,ALCAM,SEMA7A,APBB2,SEMA4G,SPTBN4,NRP2,BMP7,BMPR1B,ISPD,NOG,CHN1,SLIT2,LHX2,NRXN3,CRMP1,CSF1R,PLXNA4,BOC,KIF26A,DPYSL2,SEMA3D,CELSR3,PLXNC1,EPHB1,ERBB2,ETV1,TUBB3,EVL,SEMA4D,FYN,CHL1,GLI2,RNF165,KIF5A,L1CAM,LAMA2,MATN2,NRCAM,PAX6,SEMA5B,PLXNB1,MAPK3,RELN,PTK2,PTPRO,ROBO1,ROBO2,SEMA6D,ARX,USP33,MYCBP2,UNC5B,SPTAN1,SPTB,NFASC,FLRT2,ZIC2,DPYSL5,SEMA3B,FZD3" GO: Biological Process GO:0007422 peripheral nervous system development 1.59E-07 1.41E-03 1.85E-05 1.79E-04 29 80 "AGT,PRX,ADGRB1,ADGRB2,ARHGEF10,PLXNA4,DMD,MED12,EDNRB,HEYL,EGR3,ERBB2,ETV1,LAMA2,ADAM22,NEFH,NF1,NTRK2,SERPINI1,PMP22,FA2H,SH3TC2,SCN8A,SIRT2,NFASC,DICER1,PARD3,UGT8,LGI4" GO: Biological Process GO:0097479 synaptic vesicle localization 2.02E-07 1.78E-03 2.31E-05 2.23E-04 42 141 "SYT13,DOC2A,AMPH,CADPS,ATP2A2,SYNJ1,CACNA1A,CDH2,RIMS4,RIMS2,SNPH,DNM1,DPYSL2,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,BLOC1S2,P2RX7,NLGN3,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYT1,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0042391 regulation of membrane potential 2.80E-07 2.47E-03 3.17E-05 3.06E-04 88 391 "KCNH8,ASIC1,ADORA1,ADORA2A,ADRB2,AGT,ANK2,ATP1A1,ATP1A3,ATP1B3,ATP2A2,HCN2,MTMR2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CCK,DGKI,CHRNA4,CNGA3,CNR1,AKAP7,AKAP6,RIMS4,RIMS2,DBN1,DMD,DMPK,SHANK1,DPP6,EDN1,PTK2B,RACK1,FGF12,FGF14,FHL1,OGA,GABRB3,KCNMB4,GPER1,GRIK5,CACFD1,GRIN2C,GRIN2D,BVES,KCNB1,KCND2,KCNH2,KCNK3,KCNQ3,MEF2C,NRCAM,P2RX7,NLGN3,NALCN,FXYD1,PPP3CA,SLC26A11,RELN,PTN,PPP2R3C,PID1,SLC25A36,LRRK2,KCNIP1,STX1B,SCN2B,SCN7A,SCN8A,NLGN1,SLC8A1,SNCA,SPART,STX1A,TACR1,CUX2,TPCN2,CRTC1,KCNE5,WNT7A,KCNK12,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0060997 dendritic spine morphogenesis 2.91E-07 2.57E-03 3.26E-05 3.15E-04 20 45 "KALRN,CAMK2B,SEPT7,NGEF,SIPA1L1,DBN1,SHANK1,EPHB1,BAIAP2,PDLIM5,STAU2,ITPKA,NLGN3,RELN,LRRK2,NLGN1,CUX2,TIAM1,BHLHB9,WNT7A" GO: Biological Process GO:0042063 gliogenesis 3.00E-07 2.65E-03 3.32E-05 3.21E-04 68 279 "ADORA2A,AGT,BIN1,PRX,ASPA,SYNJ1,ARHGEF7,MYRF,IL33,CDH2,NOG,QKI,PICK1,CSF1,ARHGEF10,VCAN,DBI,DLX1,DMD,MED12,EGFR,ERBB2,ERCC2,PTK2B,PRMT5,FGFR3,DLL3,DISC1,GSN,LINGO1,IGF1,IL6ST,ITGAM,LAMA2,MATN2,MBD1,AFDN,ADAM22,MYCN,NF1,NFIX,NTRK2,NTRK3,P2RY1,PAX6,ENPP2,NLGN3,MBOAT7,FA2H,MAPK3,RELN,PTK2,PTN,SH3TC2,S100B,SIRT2,SMARCA4,SOX11,TAL1,DICER1,TIAM1,TLR4,NR2E1,PARD3,P2RY12,LGI4,PRDM8,RTN4" GO: Biological Process GO:0050768 negative regulation of neurogenesis 3.22E-07 2.85E-03 3.52E-05 3.40E-04 69 285 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,BMP7,RAB29,ARHGEF1,CBFA2T2,ARHGEF2,NOG,SLIT2,NGEF,MAP4K4,CRMP1,AATK,BRINP1,KIAA0319,DLX1,EDNRB,SEMA3D,ERBB4,CDKL3,OLFM1,FGF13,FGFR3,FOXO3,SEMA4D,DLL3,STMN2,CIT,SOX21,LINGO1,RBPJ,MBD1,MBP,MEIS1,MYCN,NF1,NTRK3,PAX6,GPR173,NLGN3,SEMA5B,PMP22,PPP3CA,PTK2,PTN,PTPRG,PTPRO,SEMA6D,NLGN1,SIRT2,CDK5RAP2,SOX3,SOX11,SPP1,SPART,KANK1,DICER1,HEY1,NR2E1,TTC3,EIF4ENIF1,GORASP1,WNT7A,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0030029 actin filament-based process 3.26E-07 2.88E-03 3.52E-05 3.40E-04 137 685 "ABR,ACTN1,FMNL2,ADD1,ADD2,CDC42BPA,ANK2,FGD2,APBB2,EPB41L5,GAS7,SHROOM2,SPTBN4,ARHGDIA,ARRB1,DYNLL1,ATP1A1,ATP2A2,CFLAR,WASF1,CACNA2D1,LURAP1,CAPN3,ARHGEF2,CFL2,TAOK2,SLIT2,MYL6B,CNN3,PICK1,AKAP6,BAG4,MYRIP,CDC42BPB,CSF1R,ARHGEF10,SIPA1L1,MYADM,DAPK3,DBN1,ELMO1,DMD,SHANK1,DOCK2,DNAJB6,EDN1,FRY,TENM1,EPB41,EPB41L2,PTK2B,CORO2B,DLC1,FER,FGF12,BAIAP2,MAD2L2,AGAP2,EVL,FLNC,ATP2C1,STAU2,ABLIM2,IQGAP2,INPP5K,ARFIP1,CIT,GSN,PACSIN2,NCKAP1L,SYNPO,SMAP1,MYLK2,SCIN,ITPKA,JAK2,KCNH2,KIT,MEF2C,MKLN1,DBNL,MYH3,MYO5A,MYO6,MYO7A,NF1,NTRK3,PDE4B,PDE4D,PDPK1,TMOD2,PIK3R1,FXYD1,MAGEL2,EPB41L4B,BCAS3,GDPD2,IQSEC3,RAP1GDS1,RDX,KIRREL1,AP1AR,SCN2B,MRAS,PPM1E,ASAP3,MYO18A,FHOD3,ABLIM3,CCDC88A,TTC17,LIMCH1,ARHGAP26,SPTAN1,SPTB,IQSEC2,CLASP2,KANK1,SYNE2,COBL,TACR1,MLST8,CLASP1,OBSL1,FRYL,TEK,PARD3,TPM1,TPM2,KCNE5,TSC1,PLEKHH2,WIPF1,RICTOR,SPIRE1,ACTR3B,FRMD6" GO: Biological Process GO:0007264 small GTPase mediated signal transduction 3.44E-07 3.04E-03 3.66E-05 3.54E-04 121 588 "RALGAPA1,ABR,BRAP,ADRA1B,HACE1,ARHGAP20,OGT,CDC42BPA,FGD2,MADD,ARHGDIA,ARHGDIG,ARRB1,RASL11B,DOCK11,KSR1,ARHGEF7,RAB29,WASF1,KALRN,ARHGEF25,KRIT1,ARHGEF1,DGKI,ARHGEF2,CDH2,ARHGAP33,CHN1,CHN2,ARHGAP22,SLIT2,RAB33A,RAB28,NGEF,RAB26,ARHGEF6,AATK,CSF1,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,DOCK4,ARHGAP32,ARHGAP24,ELMO1,TIAM2,RHOBTB1,RAB39B,CDON,DOCK2,EDNRA,RASGRP1,FAM13A,RASA4,TNK2,RASGRP2,RAB9B,ERBB2,DNAJC27,RASL12,DLC1,BAIAP2,AGAP2,AGAP3,PSD2,STAMBP,RASL10A,RAPGEF6,IQGAP2,RUNDC3A,RAB30,RAB40B,RABL2A,ARHGAP36,IGF1,KNDC1,INPP5B,ITPKB,SHC3,KITLG,DBNL,MYO9A,NF1,OCRL,MAPKAP1,RASGEF1B,DIRAS2,RELN,PSD,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RDX,ROBO1,LRRK2,MRAS,RASA3,PREX2,ARHGEF40,TRIM67,ARHGAP26,IQSEC2,MCF2L2,RGL1,KANK1,ARHGEF9,MCF2L,DNMBP,DOCK9,ARHGAP9,ARL10,TIAM1,RASD2,TRIO,TSC2,VAV1,HRASLS,DOCK8,SPATA13" GO: Biological Process GO:0044087 regulation of cellular component biogenesis 3.57E-07 3.16E-03 3.76E-05 3.63E-04 160 829 "ADD1,ADD2,AGT,TBC1D14,KIAA1324,APC,EPB41L5,SPTBN4,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,MTMR3,WASF1,LDLRAD4,HAP1,CBLN1,CCK,LDB2,SEPT7,CDH2,EVI5L,SLIT2,RAB33A,NRXN3,CCDC151,PICK1,BAG4,GDA,CLIP3,SNCAIP,ARHGEF10,SLITRK5,PPP1R16B,USP6NL,MYADM,ARHGAP24,HDAC4,TBC1D5,DAPK3,DBN1,SACS,SHANK1,PDCD6IP,DNAJB6,DNM1L,WDPCP,EDN1,TENM1,PAN3,EPHB1,ERCC2,SH3YL1,TBC1D16,PTK2B,DLC1,RACK1,SEC24B,FER,BAIAP2,EVL,PDLIM5,STAU2,IQGAP2,SEPT9,INPP5K,ARFIP1,PCDH17,STMN2,TPPP,GSN,NCKAP1L,ATXN2L,SYNPO,IRF8,SCIN,INSM1,LRRTM1,KIT,STMN1,LIMS1,MAP4,MAPT,MEF2C,MITF,DBNL,NTRK2,NTRK3,OXTR,P2RX7,PALM,ENPP2,TMOD2,NLGN3,PIK3R1,MAGEL2,LRRN3,MAPK9,BCAS3,PTK2,CEP97,RDX,KCTD17,KIRREL1,ROBO2,LRRK2,ATAT1,CLIP1,STX1B,AP1AR,ATXN2,FNIP1,SMPD3,SGK1,PPM1E,ASAP3,FUZ,AMBRA1,FHOD3,NLGN1,SIRT2,NAPB,ATF7IP,CDK5RAP2,SNCA,SPTAN1,SPTB,CLASP2,CLSTN2,TTBK2,PHLDB1,STX1A,KANK1,STXBP1,COBL,TACR1,MLST8,TAL1,ADGRL3,CUX2,CLASP1,TEK,THRA,BHLHB9,TLR4,TPM1,LRRC24,TSC1,FLRT2,TBC1D15,WIPF1,WNT7A,RICTOR,TRIM9,SPIRE1,TFIP11,EVI5,ACTR3B,IFT88" GO: Biological Process GO:0046578 regulation of Ras protein signal transduction 3.80E-07 3.36E-03 3.95E-05 3.82E-04 53 200 "ABR,ADRA1B,OGT,FGD2,MADD,ARHGDIA,ARRB1,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,DGKI,ARHGEF2,CDH2,NGEF,ARHGEF6,CSF1,ARHGEF10,ARHGEF4,ARHGAP24,TIAM2,DOCK2,RASGRP1,RASA4,ERBB2,DLC1,PSD2,STAMBP,IGF1,ITPKB,KITLG,NF1,MAPKAP1,PSD,IQSEC3,RASGRF1,RASGRF2,RDX,ROBO1,RASA3,PREX2,ARHGEF40,TRIM67,IQSEC2,MCF2L2,KANK1,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" GO: Biological Process GO:0050890 cognition 3.89E-07 3.44E-03 4.00E-05 3.87E-04 72 303 "ASIC1,ADCY8,FZD9,ADORA1,PTCHD1,ADRA1B,ADRB2,AMPH,PDE8B,ATP1A3,ADGRB3,BCHE,SYNJ1,CALB1,KALRN,DGKI,NOG,CHRNA4,NRXN3,CNR1,ZNF385A,CRHBP,CNTNAP2,DBI,SHANK1,RCAN1,EGFR,RCAN2,PPP1R1B,FGF13,AFF2,FYN,CHL1,HMGCR,IGF1,KIT,GPR155,SHC3,MEF2C,MEIS2,NF1,NPTX2,SLC11A2,NTRK2,OXTR,PDE1B,TMOD2,NLGN3,JAKMIP1,PRKAR1B,RELN,PTN,RASGRF1,S100B,SGK1,CPEB3,SNAP25,PLCB1,ARC,TACR1,CUX2,CRTC1,THRA,BHLHB9,VLDLR,NDRG4,SLC17A7,KCNAB1,EPM2A,AAAS,NETO1,JPH3" GO: Biological Process GO:2000026 regulation of multicellular organismal development 4.44E-07 3.92E-03 4.51E-05 4.35E-04 322 1893 "ACHE,ADCY6,ADD1,AXIN2,ADRB2,BEND6,AP2A1,AP2A2,AGT,SEMA6A,AMH,BIN1,OGT,SEMA7A,PI16,APC,EPB41L5,CPNE5,SEMA4G,ARHGDIA,ARNTL,ARRB2,ASPA,PTCH2,CHRD,NCOA1,NUMB,RIPK1,ADGRB1,ADGRB2,ADGRB3,PROM1,BMP7,BMPR1B,SYNJ1,BTK,MTMR2,C5,RAB29,MYRF,LDLRAD4,CACNA1A,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,CBLN1,KRIT1,USP2,RGN,CD86,ARHGEF1,CBFA2T2,ARHGEF2,SEPT7,CDH2,NOG,NUMBL,CHN1,SLIT2,CPNE6,NRXN3,CLTC,NGEF,FBXO7,QKI,MAP4K4,CNR1,CNTN1,AKAP6,AKAP5,MAGED1,CLOCK,CRMP1,AATK,CSF1,CSF1R,RGS6,SIPA1L1,SOCS5,PLXNA4,SLITRK5,PPP1R16B,PHF14,CTH,RIMS2,CYBB,BOC,HDAC9,MYADM,HDAC4,RASSF2,IST1,BRINP1,DBN1,KIAA0319,PARD6A,DLX1,DMD,MED12,NR1D2,CDON,SHANK1,DPYSL2,WDPCP,EDN1,EDNRA,EDNRB,HEYL,RASGRP1,SEMA3D,CELSR3,EGR3,PLXNC1,EIF4G1,EIF4G2,LRRC17,EPHB1,ERBB2,ERBB4,CDKL3,EYA1,PTK2B,RACK1,PRMT5,SEC24B,SLC9B2,FGF1,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,AGAP2,FOXO3,SEMA4D,FLT1,SYT3,PDLIM5,TRIM16,DLL3,STAU2,FYN,MEGF10,ERAP1,SYT17,DISC1,GCNT2,MSTN,GDF9,USP19,GLI2,LILRB4,GPER1,STMN2,CIT,SOX21,LINGO1,ATOH8,IRAK3,NCKAP1L,HMGCR,NEGR1,SMAP1,IGF1,NKD1,RBPJ,KNDC1,SCIN,IL6ST,IL12A,LRRTM1,ITPKA,ITPKB,KIT,L1CAM,LAMA2,LIG4,LIMS1,LMO2,SMAD1,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,MEIS2,KITLG,MITF,AFDN,MYCN,NACA,NBL1,NF1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,P2RX7,PALM,PAX6,PDCD2,ENPP2,GPR173,NLGN3,SEMA5B,PIK3R1,PLXNB1,PMP22,LRRN3,PPP3CA,PRKACB,PRKCB,MAPK7,RELN,KLK6,PSMA6,LAMA1,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PPP2R3C,FAT4,RET,RFX3,RNH1,ROBO1,ROBO2,FBXW7,LRRK2,RXRA,S100B,SALL1,SEMA6D,FNIP1,SGK1,CPEB3,FUZ,NLGN1,ANKRD6,LIMS2,SLC8A1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,BTBD7,CDK5RAP2,SMARCD3,IFT122,SNAP25,SOX3,SOX11,SOX15,SPP1,KDM4C,SPART,PBLD,CLASP2,CLSTN2,MESP1,PHLDB1,KANK1,SULF2,PLCB1,SYT1,COBL,TAL1,ADGRL3,TCF4,CUX2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,TEK,DICER1,SIRT1,ZFPM2,GPR161,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,PARD3,IL34,NR2C2,LRRC24,TRPS1,TTC3,UBC,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,ZIC2,NDRG4,CRB2,CELF4,GDPD5,ADAMTS9,TMEM178A,SEMA3B,ITM2C,FZD3,RTN4,NLRP3,IFT88" GO: Biological Process GO:0007611 learning or memory 4.59E-07 4.06E-03 4.61E-05 4.46E-04 66 271 "ASIC1,ADCY8,FZD9,ADRA1B,ADRB2,AMPH,PDE8B,ATP1A3,ADGRB3,BCHE,SYNJ1,CALB1,KALRN,DGKI,NOG,NRXN3,CNR1,ZNF385A,CRHBP,CNTNAP2,DBI,SHANK1,RCAN1,EGFR,RCAN2,PPP1R1B,FGF13,AFF2,FYN,HMGCR,IGF1,KIT,SHC3,MEF2C,MEIS2,NF1,NPTX2,SLC11A2,NTRK2,OXTR,PDE1B,TMOD2,NLGN3,PRKAR1B,RELN,PTN,RASGRF1,S100B,SGK1,CPEB3,SNAP25,PLCB1,ARC,TACR1,CUX2,CRTC1,THRA,BHLHB9,VLDLR,NDRG4,SLC17A7,KCNAB1,EPM2A,AAAS,NETO1,JPH3" GO: Biological Process GO:0097061 dendritic spine organization 4.80E-07 4.24E-03 4.76E-05 4.60E-04 22 54 "MTMR2,KALRN,CAMK2B,SEPT7,NGEF,PICK1,SIPA1L1,DBN1,SHANK1,EPHB1,BAIAP2,PDLIM5,STAU2,ITPKA,NLGN3,RELN,LRRK2,NLGN1,CUX2,TIAM1,BHLHB9,WNT7A" GO: Biological Process GO:1900006 positive regulation of dendrite development 5.27E-07 4.65E-03 5.17E-05 5.00E-04 29 84 "ACHE,NUMB,BMP7,KALRN,CAMK2B,NUMBL,AKAP5,DBN1,SHANK1,EIF4G2,CDKL3,BAIAP2,STAU2,ITPKA,OPA1,PALM,NLGN3,RELN,PTPRD,SGK1,CPEB3,NLGN1,COBL,CUX2,OBSL1,CRTC1,TIAM1,BHLHB9,VLDLR" GO: Biological Process GO:0043647 inositol phosphate metabolic process 5.48E-07 4.84E-03 5.32E-05 5.14E-04 26 71 "SYNJ1,SYNJ2,MTMR2,CALM1,MTMR7,IP6K1,PTK2B,IP6K2,IP6K3,INPP5K,GPER1,INPP1,INPP5B,ITPKA,ITPKB,OCRL,P2RY1,PLCB2,PLCD1,PTH1R,NUDT11,SCP2,SNCA,NUDT10,PLCB1,PLD4" GO: Biological Process GO:0045666 positive regulation of neuron differentiation 7.18E-07 6.34E-03 6.89E-05 6.66E-04 84 376 "ACHE,BEND6,SEMA7A,CPNE5,ARHGDIA,NCOA1,NUMB,BMP7,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,RGS6,RIMS2,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,HEYL,EIF4G1,EIF4G2,CDKL3,PTK2B,FGFR1,BAIAP2,SEMA4D,SYT3,STAU2,FYN,SYT17,DISC1,GLI2,STMN2,NEGR1,ITPKA,L1CAM,MAPT,MEF2C,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,NLGN3,PLXNB1,RELN,PTN,PTPRD,RET,ROBO1,ROBO2,SALL1,SGK1,CPEB3,NLGN1,TRIM67,SOX11,KDM4C,SYT1,COBL,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,VLDLR,NDRG4,GDPD5" GO: Biological Process GO:0045597 positive regulation of cell differentiation 7.61E-07 6.73E-03 7.23E-05 6.99E-04 180 966 "ACHE,AXIN2,BEND6,AGT,SEMA6A,BIN1,OGT,SEMA7A,APC,EPB41L5,CPNE5,ARHGDIA,ARNTL,ASPA,PTCH2,NCOA1,NUMB,RIPK1,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,BTK,KALRN,HAP1,CAMK2B,SPAG9,CD86,CBFA2T2,CDH2,NOG,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP6,AKAP5,ZNF385A,CSF1,CSF1R,RGS6,SOCS5,CTH,RIMS2,BOC,MYADM,MAML1,IST1,BRINP1,DBN1,DMD,CDON,SHANK1,EDN1,EDN3,HEYL,RASGRP1,EGR3,EIF4G1,EIF4G2,CDKL3,PTK2B,PRMT5,SLC9B2,OLFM1,FGFR1,FGFR3,BAIAP2,SUCO,FOXO3,SEMA4D,FLT1,SYT3,TRIM16,DLL3,STAU2,FYN,SYT17,DISC1,GCNT2,GLI2,KDM2B,GPER1,STMN2,ATOH8,HAS2,NCKAP1L,NEGR1,SMAP1,IFI16,IGF1,RBPJ,SCIN,IL6R,IL6ST,IL12A,INSM1,ITPKA,ITPKB,JAK2,KIT,L1CAM,LIG4,LIMS1,SMAD1,SMAD9,MAPT,MEF2C,KITLG,MSR1,NBL1,NFE2L2,NRCAM,NTRK2,NTRK3,OPA1,PALM,PAX6,PDE3A,ENPP2,NLGN3,PIK3R1,PLXNB1,MAPK9,RELN,GDPD2,PTCH1,PTK2,PTN,PTPRD,PPP2R3C,RET,RFX3,ROBO1,ROBO2,SALL1,MAPK12,SGK1,CPEB3,NLGN1,SIRT2,TRIM67,EPC1,SMARCA4,SMARCD3,SOX11,ZHX3,KDM4C,LMO3,MESP1,PLCB1,SYT1,COBL,TAL1,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,DICER1,SIRT1,THRA,TIAM1,HEY1,BHLHB9,IL34,NR2C2,VLDLR,XRCC4,NDRG4,CRB2,GDPD5,ADAMTS9,FZD3,RTN4,NLRP3" GO: Biological Process GO:0098815 modulation of excitatory postsynaptic potential 7.87E-07 6.95E-03 7.39E-05 7.14E-04 17 36 "MTMR2,RIMS2,DBN1,DMPK,SHANK1,PTK2B,NLGN3,RELN,LRRK2,STX1B,NLGN1,STX1A,CUX2,WNT7A,CELF4,NETO2,NETO1" GO: Biological Process GO:0016079 synaptic vesicle exocytosis 7.97E-07 7.04E-03 7.41E-05 7.16E-04 30 90 "SYT13,DOC2A,CADPS,ATP2A2,SYNJ1,CACNA1A,RIMS4,RIMS2,SNPH,STX2,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,C2CD4C,SYTL4,P2RX7,LRRK2,STX1B,NLGN1,NAPB,SNAP25,STX1A,STXBP1,SYN1,SYT1,SYT5,TRIM9" GO: Biological Process GO:0097480 establishment of synaptic vesicle localization 8.43E-07 7.45E-03 7.68E-05 7.42E-04 39 133 "SYT13,DOC2A,AMPH,CADPS,ATP2A2,SYNJ1,CACNA1A,RIMS4,RIMS2,SNPH,DNM1,DPYSL2,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,BLOC1S2,P2RX7,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYT1,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0048489 synaptic vesicle transport 8.43E-07 7.45E-03 7.68E-05 7.42E-04 39 133 "SYT13,DOC2A,AMPH,CADPS,ATP2A2,SYNJ1,CACNA1A,RIMS4,RIMS2,SNPH,DNM1,DPYSL2,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,BLOC1S2,P2RX7,LRRK2,STX1B,NLGN1,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYT1,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0007416 synapse assembly 8.57E-07 7.57E-03 7.72E-05 7.46E-04 42 148 "ACHE,ADGRB1,ADGRB2,ADGRB3,CACNA1A,CBLN1,CDH2,NRXN3,SLITRK5,SPOCK2,EPHB1,PDLIM5,STAU2,PCLO,LRRTM1,MEF2C,DBNL,MYO6,NRCAM,NTRK2,NTRK3,OXTR,NLGN3,SDK2,LRRN3,RELN,PTK2,PTPRD,ROBO2,NLGN1,CLSTN2,ADGRL3,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,BHLHB9,LRRC24,FLRT2,WNT7A" GO: Biological Process GO:0030900 forebrain development 8.96E-07 7.92E-03 8.00E-05 7.73E-04 89 407 "OGT,SEMA7A,APAF1,APLP1,CHRD,NCOA1,NUMB,BBS2,NRP2,HAP1,CDH2,DCLK1,NOG,NUMBL,SLIT2,LHX2,VAX2,AKAP5,NCOR1,NCOR2,CSF1R,CNTNAP2,PLXNA4,SLITRK5,DBI,DLX1,CDON,DPYSL2,EGFR,EMX2,ERBB4,EZH1,DLC1,FGF13,FGFR1,FGFR3,FYN,DISC1,PPARGC1A,GLI2,KDM2B,DCLK2,GNAO1,FUT10,ZIC5,RBPJ,AFDN,NEFH,NF1,NPY,NTRK2,OXTR,PAX6,PCDH9,MBOAT7,RELN,PTN,FAT4,CRTAC1,ROBO1,ROBO2,LRRK2,ATAT1,SALL1,TRA2B,ARX,BTBD3,SLC8A1,SMARCA4,SMARCC2,SOX3,SSTR1,SSTR2,TTBK2,PLCB1,TACC1,AGTPBP1,SATB2,RPGRIP1L,SZT2,DICER1,NR2E1,TSC1,VLDLR,WNT7A,GDPD5,PRDM8,RTN4,IFT88" GO: Biological Process GO:0021988 olfactory lobe development 9.11E-07 8.05E-03 8.05E-05 7.78E-04 18 40 "SEMA7A,SLIT2,LHX2,CSF1R,DPYSL2,ERBB4,FGFR1,PAX6,CRTAC1,ROBO1,ROBO2,LRRK2,SALL1,ARX,AGTPBP1,RPGRIP1L,DICER1,NR2E1" GO: Biological Process GO:0061001 regulation of dendritic spine morphogenesis 1.06E-06 9.40E-03 9.31E-05 8.99E-04 16 33 "KALRN,CAMK2B,NGEF,SIPA1L1,DBN1,BAIAP2,PDLIM5,STAU2,ITPKA,NLGN3,RELN,LRRK2,NLGN1,CUX2,TIAM1,BHLHB9" GO: Biological Process GO:0051648 vesicle localization 1.23E-06 1.09E-02 1.06E-04 1.03E-03 64 267 "SYT13,DOC2A,AMPH,SHROOM2,CADPS,ATP2A2,BBS2,SYNJ1,CACNA1A,HAP1,CDH2,MYRIP,SEC24C,RIMS4,RIMS2,SNPH,DCTN1,SEC16A,DNM1,DYNC1I1,DPYSL2,RASGRP1,STX2,F5,F8,SEC24B,FGF14,SYT3,DCTN2,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,BLOC1S2,MYO5A,MYO7A,P2RX7,NLGN3,LRRK2,STX1B,AP1AR,NLGN1,SEC31A,NAPB,SNAP25,SNCA,KIF13A,CLASP2,STX1A,STXBP1,SYN1,SYT1,ANKRD28,SYT5,CLASP1,GORASP1,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0016192 vesicle-mediated transport 1.52E-06 1.34E-02 1.30E-04 1.26E-03 262 1514 "ABR,ACHE,SYS1,ACTN1,ADD1,ADORA1,ADORA2A,ESYT2,ADRB2,AP2A1,AP2A2,OSBPL1A,TBC1D14,SRPX,SYT13,DOC2A,AMPH,BIN1,ANK2,APLP1,APOC1,APOC2,SPTBN4,ARRB1,ARRB2,CADPS,ASGR1,MARCH3,DYNLL1,STX16,ATP2A2,BBS2,SYNJ1,BTK,MTMR2,AP1M1,CACNA1I,CACNA1G,RAB29,CACNA1A,CALM1,KALRN,HAP1,HIP1R,SPAG9,USP6,SCARB1,AP4M1,EVI5L,COPB2,CBARP,EPS15L1,CPNE6,CLCN3,CLTB,CLTC,RAB26,PICK1,SEC31B,CRHBP,CLIP3,SEC24C,CSNK1E,CSNK1G3,RIMS4,RIMS2,RUBCN,USP6NL,GAPVD1,SNPH,ZFYVE16,KIF26A,TBC1D5,SCRN1,DCTN1,ELMO1,SNAP91,SGSM2,SEC16A,RAB39B,DNM1,DYNC1I1,DOCK2,DPYSL2,PDCD6IP,TOM1,DNM1L,GOLT1B,RASGRP1,OPTN,GOLGA7,TNK2,CALCRL,DCTN4,RABEPK,STX2,RAB9B,NCALD,SIRPB1,F5,F8,TBC1D16,PRAM1,RACK1,FCGR1A,FCGR1B,FCGR3A,FCGRT,SEC24B,FER,FGF14,BAIAP2,SCARA3,MEX3B,SEC23B,VTI1B,RGPD5,ANKFY1,SYT3,DCTN2,FOLR2,TMEM175,NBEA,ATP6V1H,ERGIC3,NSG1,HHIPL1,AP4B1,TVP23A,FYN,MEGF10,DENND2A,SYT17,CPLX2,CPLX1,WASHC2A,GHR,LOXL3,STON1,PCLO,GRIA2,GRIK5,GSN,BVES,AP4S1,HBA1,PACSIN2,NCKAP1L,GABARAPL2,HP,SMAP1,IRF8,MYLK2,IGF1,SCIN,LRRTM1,C2CD4C,KCNB1,KIF2A,KIF5A,KIT,STXBP5,LAMP2,SYTL4,LYPLAL1,LRP1B,MIA2,SCAMP5,DBNL,BLOC1S2,MSR1,NRBP2,MYO5A,MYO6,MYO7A,TBC1D25,P2RX7,TREM2,ENPP2,PDPK1,NLGN3,PIK3C2A,PIK3R1,SNX10,LRP12,MAGEL2,SH3KBP1,MAPK3,MASP1,BCAS3,VPS13C,PTK2,PTX3,RDX,SGSM1,LRRK2,STX1B,AP1AR,ATXN2,SMPD3,PEAR1,COPZ1,SH3GL3,KIF16B,MYO18A,NLGN1,SEC31A,EPN2,SLC11A1,NAPB,ELMO2,LGI3,ARFGAP1,SNAP25,SNCA,KIF13A,LMBRD1,USP33,FNBP1,ERC1,SPTAN1,SPTB,CLASP2,STX1A,STXBP1,JMJD6,VPS13A,PLCB1,SYN1,ARC,SYP,SYT1,ANKRD28,SYT5,EXOC7,CLASP1,SYNE1,AP4E1,AKTIP,ICAM5,PARD3,TSC2,UBE3A,GORASP1,VAV1,VLDLR,TBC1D15,LMF1,VSNL1,WIPF1,LAT2,WNT7A,KLC2,TRIM9,NDRG4,SPIRE1,EVI5,ADAMTS9,VPS35L,MPPE1,PLD4,AP3B2" GO: Biological Process GO:0051650 establishment of vesicle localization 1.53E-06 1.35E-02 1.30E-04 1.26E-03 61 252 "SYT13,DOC2A,AMPH,SHROOM2,CADPS,ATP2A2,BBS2,SYNJ1,CACNA1A,HAP1,MYRIP,SEC24C,RIMS4,RIMS2,SNPH,DCTN1,SEC16A,DNM1,DYNC1I1,DPYSL2,RASGRP1,STX2,F5,F8,SEC24B,FGF14,SYT3,DCTN2,SYT17,CPLX2,CPLX1,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,BLOC1S2,MYO5A,MYO7A,P2RX7,LRRK2,STX1B,AP1AR,NLGN1,SEC31A,NAPB,SNAP25,SNCA,KIF13A,CLASP2,STX1A,STXBP1,SYN1,SYT1,ANKRD28,SYT5,CLASP1,GORASP1,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0010001 glial cell differentiation 1.93E-06 1.71E-02 1.63E-04 1.57E-03 53 210 "ADORA2A,AGT,BIN1,PRX,ASPA,MYRF,CDH2,NOG,QKI,PICK1,ARHGEF10,DLX1,DMD,MED12,EGFR,ERBB2,ERCC2,PRMT5,FGFR3,DLL3,GSN,LINGO1,IGF1,IL6ST,ITGAM,LAMA2,MBD1,AFDN,ADAM22,MYCN,NF1,NFIX,NTRK2,NTRK3,PAX6,ENPP2,NLGN3,FA2H,MAPK3,RELN,SH3TC2,S100B,SIRT2,SMARCA4,SOX11,TAL1,DICER1,TLR4,NR2E1,PARD3,LGI4,PRDM8,RTN4" GO: Biological Process GO:0021772 olfactory bulb development 2.02E-06 1.79E-02 1.69E-04 1.63E-03 17 38 "SLIT2,LHX2,CSF1R,DPYSL2,ERBB4,FGFR1,PAX6,CRTAC1,ROBO1,ROBO2,LRRK2,SALL1,ARX,AGTPBP1,RPGRIP1L,DICER1,NR2E1" GO: Biological Process GO:0010657 muscle cell apoptotic process 2.08E-06 1.84E-02 1.72E-04 1.66E-03 25 71 "AGT,APAF1,ARRB1,ARRB2,BMP7,CAMK2A,QKI,DMPK,EDN1,ERBB4,PTK2B,APOPT1,HMGCR,IGF1,RBPJ,IL12A,JAK2,LIFR,NACA,NFE2L2,PDPK1,PIK3R1,RPS6KA2,DICER1,SIRT1" GO: Biological Process GO:0099565 "chemical synaptic transmission, postsynaptic" 2.12E-06 1.87E-02 1.73E-04 1.67E-03 33 108 "ADORA1,ADORA2A,ADRB2,ARRB2,MTMR2,DGKI,CHRNA4,RIMS2,DBN1,DMPK,SHANK1,PTK2B,GABRA3,GABRB3,GABRG2,GRIK5,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,RELN,LRRK2,STX1B,NLGN1,SNCA,STX1A,CUX2,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0050775 positive regulation of dendrite morphogenesis 2.18E-06 1.93E-02 1.77E-04 1.71E-03 18 42 "ACHE,NUMB,KALRN,CAMK2B,NUMBL,AKAP5,DBN1,CDKL3,BAIAP2,STAU2,ITPKA,RELN,PTPRD,SGK1,CUX2,OBSL1,TIAM1,BHLHB9" GO: Biological Process GO:0090066 regulation of anatomical structure size 2.78E-06 2.45E-02 2.23E-04 2.15E-03 110 544 "ADCY6,ADD1,ADD2,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,SEMA6A,OGT,SEMA7A,SHROOM2,AQP6,SEMA4G,SPTBN4,ATP2B2,BBS2,CACNA1G,WASF1,CBS,CD38,CFL2,SLIT2,CLCN3,PICK1,BAG4,CPS1,AATK,PLXNA4,DOCK4,MYADM,IST1,DBN1,DPYSL2,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,EGFR,PLXNC1,EIF4G2,TENM1,CDKL3,MRVI1,PTK2B,FER,OLFM1,FGF13,BAIAP2,EVL,SEMA4D,IQGAP2,DISC1,ARFIP1,KCNMB4,GPER1,CIT,GSN,GUCY1A1,NCKAP1L,HMGCR,SCIN,L1CAM,MAPT,DBNL,NRCAM,NTRK3,OXTR,P2RX7,P2RY1,TMOD2,SEMA5B,PIK3C2A,MAGEL2,PTK2,RAP1GDS1,RDX,RET,KIRREL1,LRRK2,AP1AR,SEMA6D,SMPD3,FHOD3,SLC8A1,SLC12A2,SLC12A4,SPP1,SPTAN1,SPTB,SPART,CLASP2,KANK1,TACR1,MLST8,SIRT1,LRRC8A,TSC1,TSC2,PLEKHH2,VAV1,WIPF1,WNT7A,RICTOR,SPIRE1,SEMA3B,RTN4,ACTR3B" GO: Biological Process GO:0010721 negative regulation of cell development 3.08E-06 2.72E-02 2.45E-04 2.37E-03 78 354 "ADCY6,SEMA6A,SEMA7A,PI16,SEMA4G,ARHGDIA,BMP7,RAB29,LDLRAD4,ARHGEF1,CBFA2T2,ARHGEF2,NOG,SLIT2,NGEF,MAP4K4,CRMP1,AATK,BRINP1,KIAA0319,DLX1,EDNRB,SEMA3D,ERBB4,CDKL3,OLFM1,FGF13,FGFR3,MAD2L2,FOXO3,SEMA4D,DLL3,STMN2,CIT,SOX21,LINGO1,IGF1,RBPJ,MBD1,MBP,MEIS1,MYCN,NF1,NPR2,NTRK3,PAX6,GPR173,NLGN3,SEMA5B,PMP22,PPP3CA,PTK2,PTN,PTPRG,PTPRO,AP1AR,SALL1,SEMA6D,FUZ,NLGN1,SIRT2,CDK5RAP2,SOX3,SOX11,SPP1,SPART,PBLD,KANK1,DICER1,HEY1,NR2E1,TTC3,EIF4ENIF1,GORASP1,WNT7A,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0043085 positive regulation of catalytic activity 3.13E-06 2.76E-02 2.47E-04 2.39E-03 271 1588 "RALGAPA1,ABR,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADORA2A,ADRB2,AGT,TBC1D14,OSBPL8,TAOK1,ARHGAP20,ALK,AMPH,BIN1,OGT,FGD2,C6orf89,MAP4K3,PKP4,APAF1,APOC1,APOC2,CDC14B,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,BID,CFLAR,ARHGEF7,C5,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,SPAG9,ARHGEF25,CCK,CCNH,CCNT1,RGN,ARHGEF1,SCARB1,ARHGEF2,CDC25B,ARHGAP33,EVI5L,RCBTB2,CHN1,CHN2,TAOK2,ARHGAP22,PLAA,NGEF,ARHGEF6,AKAP6,AKAP5,MAGED1,NRG2,CSF1,CSF1R,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,RASSF2,TBC1D5,DAPK1,GIT2,ELMO1,B3GAT3,TIAM2,SGSM2,DOCK2,CASP8AP2,ARRDC4,DUSP9,DNAJB6,FIS1,EDN1,EDN3,EDNRA,RASGRP1,FAM13A,APH1A,EGFR,RASA4,EIF5,TENM1,RGS17,PCOLCE2,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,TAOK3,DLC1,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,PRKAG2,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,CAMKK2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GHR,MALT1,RUNDC3A,COPS8,DBF4,GNAL,GNAO1,ADAP1,GPER1,GRIN2C,GRIN2D,GSN,MAP4K5,NCKAP1L,TNFAIP8L3,ARHGAP36,GABARAPL2,AGFG1,SMAP1,IFI16,IGF1,KNDC1,IL6R,INPP5B,JAK2,KIT,STXBP5,LIMS1,SHC3,MEF2C,MIA2,KITLG,AFDN,MMP16,MMP17,GIT1,DBNL,MYO9A,NF1,SLC11A2,NTRK3,TBC1D25,OCRL,P2RX7,PDCD2,PDPK1,PFKFB2,PKD1,PLCB2,PLXNB1,RASGEF1B,PRKACB,PRKAR1B,MAPK3,MAPK9,MAPK10,DIRAS2,RELN,PSD,BCAS3,PSMA6,PTK2,PPP2R3C,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS12,RIC8B,DCUN1D2,ROBO1,FBXW7,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,RASA3,ASAP3,AMBRA1,PREX2,ARHGEF40,CCDC88A,SLC11A1,ARFGAP1,MAPKBP1,SNCA,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,DNAJC9,PLCB1,MTCL1,MCF2L,DNMBP,TCEA1,DOCK9,ARHGAP9,TEK,SIRT1,TIAM1,TLR4,PIK3R5,TPM1,TRIO,TSC1,TSC2,UBC,BCL2L13,MTCH1,VAV1,VIPR2,VLDLR,TBC1D15,LMF1,P2RY12,WRN,RICTOR,XRCC4,MAP3K12,EVI5,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:0044093 positive regulation of molecular function 3.23E-06 2.86E-02 2.53E-04 2.44E-03 316 1893 "RALGAPA1,ABR,ADCY5,ADCY6,ADCY8,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,ADRB2,AGT,TBC1D14,OSBPL8,TAOK1,ARHGAP20,ALK,AMH,AMPH,BIN1,OGT,ANK2,FGD2,C6orf89,MAP4K3,PKP4,APAF1,EPB41L5,APOC1,APOC2,CDC14B,MADD,SPTBN4,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,BID,CFLAR,ARHGEF7,BTK,C5,CACNA2D1,CALM1,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CAPN3,SPAG9,ARHGEF25,CCK,KRIT1,CCNH,CCNT1,RGN,ARHGEF1,SCARB1,SYNGR3,ARHGEF2,CDC25B,ARHGAP33,LRRFIP1,EVI5L,RCBTB2,CHN1,CHN2,TAOK2,ARHGAP22,PLAA,NGEF,ARHGEF6,AKAP7,AKAP6,AKAP5,MAGED1,NRG2,CLOCK,CSF1,CSF1R,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,CTH,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,TCAF1,ARHGAP24,HDAC4,RASSF2,TBC1D5,DAPK1,GIT2,ELMO1,B3GAT3,TIAM2,SGSM2,DMD,DOCK2,CASP8AP2,ARRDC4,DUSP9,DNAJB6,FIS1,EDN1,EDN3,EDNRA,HIPK3,RASGRP1,FAM13A,APH1A,EGFR,RASA4,EIF5,TENM1,RGS17,PCOLCE2,EPB41,RASGRP2,ERBB2,ERBB4,ERCC2,DENND4A,TBC1D16,PTK2B,TAOK3,DLC1,RACK1,STRADA,FER,FGF1,FGF13,FGF14,FGFR1,FGFR3,PRKAG2,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,CAMKK2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,DBF4,GNAL,GNAO1,ADAP1,GPER1,GRIN2C,GRIN2D,GSN,MAP4K5,IRAK3,NCKAP1L,TNFAIP8L3,ARHGAP36,GABARAPL2,AGFG1,SMAP1,IFI16,IGF1,KNDC1,IL6R,INPP5B,JAK2,KIT,STXBP5,LIMS1,SHC3,MEF2C,MIA2,KITLG,AFDN,MMP16,MMP17,GIT1,DBNL,MYO9A,NDP,NF1,SLC11A2,NTRK3,TBC1D25,OCRL,P2RX7,PDCD2,PDPK1,CYTL1,PFKFB2,NLGN3,PKD1,PLCB2,PLCL1,PLXNB1,PPP3CA,RASGEF1B,PRKACB,PRKAR1B,PRKCB,MAPK3,MAPK9,MAPK10,DIRAS2,RELN,PSD,BCAS3,PSMA6,PTK2,PPP2R3C,IQSEC3,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS12,RIC8B,DCUN1D2,ROBO1,FBXW7,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,RASA3,SGK1,ASAP3,AMBRA1,PREX2,KDM4D,ARHGEF40,SIRT2,CCDC88A,SLC11A1,ARFGAP1,SMARCA4,MAPKBP1,SNCA,USP33,FNBP1,ERC1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,ARHGEF9,DNAJC9,PLCB1,ARC,MTCL1,MCF2L,DNMBP,TCEA1,DOCK9,ARHGAP9,CRTC1,TEK,SIRT1,AKTIP,TIAM1,TLR4,PIK3R5,TP53BP1,TPM1,TRIO,TSC1,TSC2,SGK3,UBC,BCL2L13,MTCH1,VAV1,VIPR2,VLDLR,TBC1D15,LMF1,P2RY12,WRN,RICTOR,XRCC4,ZIC2,MAP3K12,EVI5,WNK3,WNK2,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 3.40E-06 3.00E-02 2.63E-04 2.55E-03 34 115 "ADORA1,ADORA2A,ADRB2,ARRB2,MTMR2,DGKI,CHRNA4,RIMS2,DBN1,DMPK,SHANK1,PTK2B,GABRA3,GABRB3,GABRG2,GLI2,GRIK5,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,RELN,LRRK2,STX1B,NLGN1,SNCA,STX1A,CUX2,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling 4.22E-06 3.73E-02 3.23E-04 3.12E-03 44 167 "AGT,CD86,NRG2,NCOR1,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,AGAP2,SEMA4D,FLT1,STAMBP,FYN,GPER1,IGF1,JAK2,KIT,PIK3AP1,KITLG,NF1,NTRK2,PIK3R1,PLXNB1,MAPK3,RELN,PTK2,PTPN13,PREX2,SIRT2,MYO16,UNC5B,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1" GO: Biological Process GO:0051588 regulation of neurotransmitter transport 4.24E-06 3.75E-02 3.23E-04 3.12E-03 26 78 "ASIC1,ADORA2A,ATP2A2,CACNA1A,CACNA1B,CAMK2A,SNCAIP,RIMS4,RIMS2,EDN3,KCNMB4,GPER1,GRIK5,GRM8,ICA1,MEF2C,NF1,NTRK2,LRRK2,STX1B,NLGN1,NAPB,SNCA,STX1A,STXBP1,SYN1" GO: Biological Process GO:0021537 telencephalon development 4.53E-06 4.00E-02 3.42E-04 3.31E-03 61 260 "SEMA7A,NCOA1,NUMB,BBS2,NRP2,CDH2,NUMBL,SLIT2,LHX2,AKAP5,NCOR2,CSF1R,CNTNAP2,PLXNA4,SLITRK5,DBI,DLX1,CDON,DPYSL2,EGFR,EMX2,ERBB4,EZH1,FGF13,FGFR1,DISC1,KDM2B,DCLK2,FUT10,AFDN,NEFH,NF1,NPY,NTRK2,OXTR,PAX6,MBOAT7,RELN,FAT4,CRTAC1,ROBO1,ROBO2,LRRK2,ATAT1,SALL1,TRA2B,ARX,BTBD3,SLC8A1,PLCB1,TACC1,AGTPBP1,RPGRIP1L,SZT2,DICER1,NR2E1,TSC1,VLDLR,PRDM8,RTN4,IFT88" GO: Biological Process GO:0051932 "synaptic transmission, GABAergic" 4.80E-06 4.24E-02 3.59E-04 3.47E-03 19 48 "SYN3,ADORA1,ADORA2A,CACNA1A,CACNB4,HAP1,CLCN3,CNR1,DBI,DNM1,ERBB4,GABRB3,GABRG2,NF1,OXTR,PLCL1,NLGN1,STXBP1,TACR1" GO: Biological Process GO:2000310 regulation of NMDA receptor activity 6.08E-06 5.37E-02 4.52E-04 4.36E-03 10 16 "CRHBP,DAPK1,PTK2B,PPARGC1A,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1" GO: Biological Process GO:0017156 calcium ion regulated exocytosis 6.24E-06 5.51E-02 4.59E-04 4.44E-03 37 133 "SYT13,DOC2A,CADPS,ATP2A2,SYNJ1,CACNA1I,CACNA1G,CACNA1A,CBARP,RIMS4,RIMS2,SNPH,STX2,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,SCIN,C2CD4C,KCNB1,SYTL4,SCAMP5,P2RX7,LRRK2,STX1B,NLGN1,NAPB,SNAP25,STX1A,STXBP1,PLCB1,SYN1,SYT1,SYT5,TRIM9" GO: Biological Process GO:0010976 positive regulation of neuron projection development 6.91E-06 6.11E-02 5.05E-04 4.88E-03 65 286 "ACHE,SEMA7A,CPNE5,ARHGDIA,NUMB,BMP7,KALRN,HAP1,CAMK2B,CBFA2T2,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,RIMS2,IST1,DBN1,DMD,SHANK1,EIF4G2,CDKL3,PTK2B,FGFR1,BAIAP2,SEMA4D,SYT3,STAU2,FYN,SYT17,DISC1,STMN2,NEGR1,ITPKA,L1CAM,MAPT,NFE2L2,NTRK2,NTRK3,OPA1,PALM,NLGN3,PLXNB1,RELN,PTN,PTPRD,RET,ROBO1,ROBO2,SGK1,CPEB3,NLGN1,TRIM67,SYT1,COBL,CUX2,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,VLDLR,NDRG4" GO: Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential 7.19E-06 6.35E-02 5.21E-04 5.03E-03 13 26 "RIMS2,DBN1,SHANK1,PTK2B,NLGN3,RELN,STX1B,NLGN1,STX1A,CUX2,WNT7A,NETO2,NETO1" GO: Biological Process GO:0046434 organophosphate catabolic process 7.76E-06 6.86E-02 5.58E-04 5.39E-03 45 176 "ABHD6,AMPD3,OGT,APOC1,APOC2,PLA2G4C,PDE8B,SYNJ1,SYNJ2,MTMR2,MTMR7,SCARB1,ENTPD2,ENTPD4,NCOR1,GDA,PNPLA8,HDAC4,ENPP6,GMPR2,RACK1,PRKAG2,INPP5K,GCK,PPARGC1A,GPD1,IGF1,INPP1,NCF2,OGG1,P2RX7,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PPARA,MAPK7,SMPD3,SMUG1,NEIL2,PRTFDC1,NT5M" GO: Biological Process GO:0051494 negative regulation of cytoskeleton organization 9.26E-06 8.18E-02 6.60E-04 6.38E-03 36 130 "ADD1,ADD2,APC,SHROOM2,SPTBN4,ARHGEF2,SLIT2,PICK1,CLIP3,MYADM,DBN1,SHANK1,APC2,DLC1,FGF13,EVL,INPP5K,STMN2,GSN,SCIN,STMN1,MID1,DBNL,TMOD2,RDX,MAP6D1,SGK1,FHOD3,CDK5RAP2,SNCA,SPTAN1,SPTB,CLASP2,KANK1,CLASP1,PLEKHH2" GO: Biological Process GO:0050770 regulation of axonogenesis 9.42E-06 8.33E-02 6.66E-04 6.44E-03 47 188 "ACHE,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,CACNA1A,ARHGEF1,CDH2,CHN1,SLIT2,AATK,SIPA1L1,PLXNA4,IST1,DBN1,DPYSL2,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,FGF13,SEMA4D,DISC1,LINGO1,L1CAM,MAP2,MAPT,MBP,NRCAM,NTRK2,NTRK3,SEMA5B,PLXNB1,PTK2,PTPRO,RET,ROBO1,ROBO2,SEMA6D,SPP1,SPART,CLASP2,TIAM1,WNT7A,SEMA3B,RTN4" GO: Biological Process GO:0060341 regulation of cellular localization 9.93E-06 8.77E-02 6.96E-04 6.73E-03 242 1416 "ABR,ASIC1,ACHE,ADCY5,AXIN2,ADORA1,ADORA2A,AGT,C1QTNF1,C1QTNF3,SYT13,DOC2A,OGT,DPP10,ANK2,KCNAB2,APC,MADD,ARNTL,ARRB1,RGS20,CADPS,PDE8B,NUMB,DYNLL1,ATP2A2,BARD1,BID,BMP7,SYNJ1,ARHGEF7,MTMR2,CACNA1I,CACNA1G,C5,RAB29,IL33,CACNA1A,CACNA1B,CALM1,KALRN,HAP1,CAMK2A,CAPN3,CCK,CD38,CDH2,DCLK1,CACNA2D2,CBARP,CHRNA4,CLTC,HECTD1,MAP4K4,RAB26,CNR1,AKAP6,CABP1,AKAP5,BAG4,MYRIP,CLOCK,CRHBP,CRY2,CLIP3,SNCAIP,CSF1R,CSNK1E,RIMS4,APPL1,RIMS2,TCAF1,DBI,DBN1,B3GAT3,C2CD2L,PARD6A,DMD,DNM1,DPP6,DPYSL2,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EDNRA,RASGRP1,EGFR,TENM1,ERBB2,ERBB4,APC2,DNAJC27,TLR7,REEP2,PTK2B,PRAM1,RACK1,SEC24B,FER,FGF14,FGFR1,VTI1B,SYT3,ZBED3,TRIM16,PRELID3A,OGA,FYN,GABBR1,SYT17,INPP5K,CPLX2,CPLX1,GCK,ARFIP1,GDF9,PCDH17,GLUL,KCNMB4,DCLK2,GPER1,PCLO,GRIK5,GRM8,GSN,KAT7,BVES,HMGCR,HNMT,HSPA1L,ICA1,MYLK2,IGF1,C2CD4C,JAK2,KCNB1,KCNN3,IPO5,STXBP5,SYTL4,MAPT,LYPLAL1,MEF2C,SCAMP5,MXI1,MYO5A,MYT1,HNRNPM,NEFH,NELL2,NF1,NNAT,NTRK2,NUCB2,OGG1,OXTR,P2RX7,P2RY1,TREM2,PAX6,PDE1C,PDE4D,PDPK1,PFKFB2,ZDHHC8,NLGN3,PIK3R1,PKD1,PLCD1,PPM1B,PPP3CA,PPP3CC,RANBP3L,PKIA,PRKCB,MAPK3,MAPK7,BCAS3,PTN,PID1,SH3TC2,RDX,RFX3,FBXW7,LRRK2,STX1B,SCP2,SMPD3,MYO18A,SYBU,NLGN1,ABLIM3,SLC8A1,SIRT2,CDK5RAP3,NAPB,LGI3,SNAP25,SNCA,SOX11,PBLD,CLASP2,TTBK2,STX1A,KANK1,SULF2,STXBP1,PLCB1,SYN1,SYT1,ASTN2,SYT5,TACR1,MTCL1,FBXW11,CLASP1,TEK,SIRT1,THRA,TIAM1,TLR4,PARD3,TP53BP2,STXBP4,TRPM2,VSNL1,WIPF1,P2RY12,XPO1,ZIC1,TRIM9,NDRG4,REEP1,MFF,HPS4,WNK3,RTN4,NLRP3,AAAS,JPH3" GO: Biological Process GO:0032271 regulation of protein polymerization 1.00E-05 8.85E-02 6.97E-04 6.73E-03 46 183 "ADD1,ADD2,APC,SPTBN4,WASF1,SLIT2,PICK1,BAG4,GDA,CLIP3,MYADM,DBN1,TENM1,PTK2B,FER,BAIAP2,EVL,IQGAP2,ARFIP1,STMN2,TPPP,GSN,NCKAP1L,SCIN,STMN1,MAPT,DBNL,TMOD2,MAGEL2,RDX,KIRREL1,CLIP1,AP1AR,SGK1,FHOD3,SNCA,SPTAN1,SPTB,CLASP2,KANK1,MLST8,CLASP1,WIPF1,RICTOR,SPIRE1,ACTR3B" GO: Biological Process GO:0021987 cerebral cortex development 1.15E-05 1.02E-01 7.97E-04 7.70E-03 34 121 "NCOA1,BBS2,NRP2,CDH2,SLIT2,LHX2,CNTNAP2,CDON,EGFR,EMX2,FGF13,FGFR1,DISC1,FUT10,AFDN,NEFH,NF1,NPY,NTRK2,PAX6,MBOAT7,RELN,FAT4,ROBO1,TRA2B,ARX,BTBD3,PLCB1,TACC1,DICER1,NR2E1,TSC1,VLDLR,RTN4" GO: Biological Process GO:0031346 positive regulation of cell projection organization 1.24E-05 1.10E-01 8.50E-04 8.21E-03 78 367 "ACHE,SEMA7A,APC,CPNE5,ARHGDIA,NUMB,BMP7,ARHGEF7,KALRN,HAP1,CAMK2B,CBFA2T2,SEPT7,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,RIMS2,HDAC4,IST1,DBN1,DMD,SHANK1,EIF4G2,TENM1,CDKL3,PTK2B,FGFR1,BAIAP2,SEMA4D,SYT3,STAU2,FYN,SYT17,DISC1,SEPT9,STMN2,NEGR1,ITPKA,KIT,L1CAM,MAPT,NFE2L2,NTRK2,NTRK3,OPA1,P2RX7,PALM,ENPP2,NLGN3,PLXNB1,RELN,BCAS3,PTN,PTPRD,RET,KCTD17,ROBO1,ROBO2,SGK1,CPEB3,FUZ,NLGN1,TRIM67,TTBK2,SYT1,COBL,CUX2,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,VLDLR,NDRG4" GO: Biological Process GO:0060996 dendritic spine development 1.26E-05 1.12E-01 8.58E-04 8.29E-03 27 87 "KALRN,CAMK2B,SEPT7,NGEF,SIPA1L1,DBN1,SHANK1,EIF4G2,EPHB1,ACSL4,BAIAP2,PDLIM5,STAU2,DISC1,ITPKA,MEF2C,GIT1,PALM,NLGN3,RELN,LRRK2,CPEB3,NLGN1,CUX2,TIAM1,BHLHB9,WNT7A" GO: Biological Process GO:0061003 positive regulation of dendritic spine morphogenesis 1.30E-05 1.15E-01 8.78E-04 8.48E-03 10 17 "KALRN,CAMK2B,DBN1,BAIAP2,STAU2,ITPKA,RELN,CUX2,TIAM1,BHLHB9" GO: Biological Process GO:0060627 regulation of vesicle-mediated transport 1.47E-05 1.30E-01 9.86E-04 9.53E-03 101 508 "ABR,ADD1,TBC1D14,SYT13,DOC2A,BIN1,APOC1,APOC2,ARRB1,ARRB2,CADPS,ATP2A2,SYNJ1,MTMR2,CACNA1I,CACNA1G,CACNA1A,HAP1,USP6,SCARB1,EVI5L,CBARP,RAB26,PICK1,CLIP3,RIMS4,RIMS2,RUBCN,USP6NL,SNPH,ZFYVE16,TBC1D5,SNAP91,SGSM2,DNM1,DOCK2,PDCD6IP,TNK2,SIRPB1,TBC1D16,PRAM1,RACK1,FCGR1A,SEC24B,FER,FGF14,MEX3B,ANKFY1,SYT3,SYT17,CPLX2,CPLX1,STON1,PCLO,GRIK5,BVES,PACSIN2,NCKAP1L,SMAP1,LRRTM1,C2CD4C,KCNB1,STXBP5,SYTL4,LYPLAL1,SCAMP5,MYO5A,TBC1D25,PDPK1,MAPK3,PTK2,PTX3,RDX,SGSM1,LRRK2,STX1B,ATXN2,SMPD3,NLGN1,EPN2,SLC11A1,NAPB,LGI3,ARFGAP1,SNCA,CLASP2,STX1A,STXBP1,PLCB1,SYN1,SYT1,SYT5,CLASP1,SYNE1,PARD3,TSC2,TBC1D15,VSNL1,TRIM9,NDRG4,EVI5" GO: Biological Process GO:0044089 positive regulation of cellular component biogenesis 1.48E-05 1.31E-01 9.86E-04 9.53E-03 92 453 "AGT,KIAA1324,APC,EPB41L5,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,WASF1,HAP1,CBLN1,CCK,LDB2,SEPT7,CDH2,NRXN3,PICK1,BAG4,GDA,ARHGEF10,SLITRK5,HDAC4,PDCD6IP,EDN1,TENM1,PAN3,EPHB1,ERCC2,PTK2B,RACK1,FER,BAIAP2,EVL,STAU2,IQGAP2,SEPT9,ARFIP1,TPPP,GSN,NCKAP1L,SYNPO,IRF8,SCIN,LRRTM1,KIT,LIMS1,MAPT,MITF,NTRK2,NTRK3,OXTR,P2RX7,PALM,ENPP2,NLGN3,MAGEL2,LRRN3,MAPK9,BCAS3,KCTD17,KIRREL1,ATAT1,CLIP1,AP1AR,FNIP1,PPM1E,FUZ,NLGN1,CLASP2,CLSTN2,TTBK2,PHLDB1,COBL,TACR1,MLST8,TAL1,ADGRL3,CUX2,CLASP1,TEK,BHLHB9,TLR4,TPM1,LRRC24,TSC1,FLRT2,WIPF1,WNT7A,RICTOR,SPIRE1,ACTR3B" GO: Biological Process GO:0007163 establishment or maintenance of cell polarity 1.68E-05 1.48E-01 1.11E-03 1.07E-02 45 181 "APC,DST,KRIT1,ARHGEF2,LHX2,CDC42BPB,SNAP91,PARD6A,DOCK2,WDPCP,EPHB1,EYA1,PTK2B,RACK1,FGF13,BRSK1,GSN,NCKAP1L,IGF1,LIMS1,MAP2,MAP4,PAX6,PKD1,GPSM2,BCAS3,LAMA1,PTK2,SPDL1,FERMT1,MYO18A,CDK5RAP2,CLASP2,ERBIN,KANK1,SYNE2,MTCL1,RPGRIP1L,CLASP1,TEK,HEY1,PARD3,WNT7A,RICTOR,CRB2" GO: Biological Process GO:0010660 regulation of muscle cell apoptotic process 1.73E-05 1.53E-01 1.13E-03 1.09E-02 22 65 "AGT,ARRB1,ARRB2,BMP7,CAMK2A,QKI,EDN1,ERBB4,PTK2B,APOPT1,HMGCR,IGF1,RBPJ,IL12A,JAK2,LIFR,NACA,NFE2L2,PDPK1,PIK3R1,DICER1,SIRT1" GO: Biological Process GO:0060998 regulation of dendritic spine development 1.73E-05 1.53E-01 1.13E-03 1.09E-02 22 65 "KALRN,CAMK2B,NGEF,SIPA1L1,DBN1,SHANK1,EIF4G2,BAIAP2,PDLIM5,STAU2,DISC1,ITPKA,MEF2C,PALM,NLGN3,RELN,LRRK2,CPEB3,NLGN1,CUX2,TIAM1,BHLHB9" GO: Biological Process GO:0006468 protein phosphorylation 1.80E-05 1.59E-01 1.16E-03 1.12E-02 319 1952 "KCNH8,CLK4,NDRG2,ADCY5,ADCY6,ADCY8,AXIN2,BRAP,ADORA1,ADORA2A,ADRA1B,ADRB2,AGT,OSBPL8,TAOK1,C1QTNF1,C1QTNF3,ALK,OGT,CDC42BPA,SEMA7A,FGD2,MAP4K3,APC,CDK10,MADD,CASK,SPTBN4,ZFYVE28,ARRB1,ARRB2,CDK13,STK33,MARK4,EIF4G3,RIPK1,BLM,KSR1,BMP7,BMPR1B,BTK,C5,LDLRAD4,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,SPAG9,CBS,CCK,CCNH,CCNT1,RGN,ARHGEF2,CDC25B,CDH2,DCLK1,TBRG4,NOG,CRLF1,SOCS6,TAOK2,SLIT2,FBXO7,MAP4K4,ARHGEF6,PICK1,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,NRG2,CDC42BPB,NCOR1,CLIP3,AATK,CSF1,CSF1R,CSF2RA,CSNK1E,CSNK1G3,SOCS5,MYADM,RASSF2,MAML1,DAPK1,DAPK3,PARD6A,DMD,DMPK,RPS6KL1,CDON,DUSP9,EDN1,EDN3,EDNRA,EDNRB,HIPK3,RASGRP1,CELSR3,EGFR,RASA4,IRAK4,TENM1,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,TLR7,RPS6KC1,PTK2B,TAOK3,RACK1,FKTN,STRADA,PRMT5,PPP1R1B,FECH,FER,FGF1,FGF12,FGF13,FGF14,FGFR1,FGFR3,MAD2L2,PRKAG2,MEX3B,AGAP2,SEMA4D,FLT1,WDR83,ZBED3,CAMKK2,BRSK1,FYB1,FYN,ZNF274,IP6K3,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,TTBK1,COPS8,DCLK2,GPER1,GPR37,CNTRL,C1QL4,GRIN2C,GRIN2D,CIT,MAP4K5,IRAK3,NCKAP1L,TNFAIP8L3,HMGCR,MYLK2,IGF1,NIM1K,KNDC1,IL6R,IL6ST,IL12A,INSM1,LRRTM1,ITPKA,ITPKB,JAK2,KCNH2,KIT,CAMK2N2,SMAD1,SMAD9,PIK3AP1,MARK1,MARK3,MATK,SHC3,MEF2C,KITLG,MID1,PPM1L,DBNL,NRBP2,NEK1,NF1,NPR2,NTRK2,NTRK3,KSR2,OPRL1,OXTR,P2RX7,P2RY1,TREM2,PAX6,CDK18,PDE4D,ENPP2,PDPK1,DUSP26,PIK3R1,PKD1,PLCL1,PPP1R1A,LRRN3,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,DIRAS2,RELN,PSMA6,LAMA1,SNRK,PTK2,STK32A,PPP2R3C,PID1,RASGRF1,RASGRF2,DUSP15,RET,RGS3,RGS4,RNASEL,KIRREL1,NEK11,EPHA10,FBXW7,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,FNIP1,TNFRSF19,RASA3,SGK1,PPM1E,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,MAST1,MAPKBP1,SNCA,LMBRD1,DOK5,ERC1,DBNDD2,SPTAN1,SPTB,CDK19,TSPYL2,LMO3,PBLD,SAMSN1,ST5,MPRIP,NEK4,TTBK2,PLCB1,MLST8,FBXW11,NSD1,SIK3,TEK,DICER1,SIRT1,AKTIP,TIAM1,TLR4,PARD3,PIK3R5,CDK20,IL34,NR2C2,TRIO,TSC1,TSC2,SGK3,UBC,UCHL1,FLRT2,VLDLR,WNT7A,RICTOR,NDRG4,MAP3K12,WNK3,WNK2,NELFE,SOCS4" GO: Biological Process GO:0051129 negative regulation of cellular component organization 1.88E-05 1.66E-01 1.20E-03 1.16E-02 128 680 "ADCY6,ADD1,ADD2,SEMA6A,OGT,SEMA7A,APC,APOC1,APOC2,SHROOM2,SEMA4G,SPTBN4,ARHGDIA,ARRB2,NUMB,CFLAR,BMP7,MTMR2,RAB29,LDLRAD4,ARHGEF1,CBFA2T2,ARHGEF2,EVI5L,SLIT2,CLTC,NGEF,HECTD1,MAP4K4,PICK1,BAG4,CRMP1,CLIP3,AATK,CST3,RUBCN,MYADM,SNPH,ARHGAP24,DBN1,KIAA0319,SACS,SHANK1,DNAJB6,SEMA3D,APC2,CDKL3,DLC1,RACK1,FGF13,FGFR3,MAD2L2,EVL,SEMA4D,INPP5K,PPARGC1A,STMN2,CIT,GSN,LINGO1,IRAK3,PACSIN2,IGF1,RBPJ,SCIN,LRRTM1,STMN1,MAP4,LYPLAL1,MBP,SCAMP5,MID1,DBNL,OPA1,TMOD2,NLGN3,SEMA5B,PMP22,PPP3CA,BCAS3,VPS13C,PTK2,PTN,PTPRG,PTPRO,PID1,CEP97,RDX,ROBO2,RPS6KA2,MAP6D1,LRRK2,AP1AR,SALL1,SEMA6D,ATXN2,SGK1,FUZ,FHOD3,NLGN1,KDM4D,SIRT2,TET1,CDK5RAP2,SNCA,KDM4B,KDM3A,SPP1,KDM4C,SPTAN1,SPTB,SPART,PBLD,CLASP2,KANK1,SMG6,CLASP1,SIRT1,THRA,TTC3,GORASP1,PLEKHH2,TOM1L2,TRIM9,TFIP11,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0043242 negative regulation of protein complex disassembly 1.95E-05 1.72E-01 1.24E-03 1.20E-02 23 70 "ADD1,ADD2,APC,SHROOM2,SPTBN4,ARHGEF2,APC2,FGF13,EVL,STMN2,GSN,IRAK3,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SPTAN1,SPTB,CLASP2,CLASP1,PLEKHH2" GO: Biological Process GO:0043269 regulation of ion transport 2.12E-05 1.87E-01 1.34E-03 1.29E-02 126 669 "KCNH8,ADORA1,ADORA2A,ADRB2,AGT,DPP10,ANK2,KCNAB2,CASK,SPTBN4,ARRB2,ATP1A1,ATP1B3,ATP2B2,RIPK1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2G,CAPN3,CCK,RGN,KCNAB3,CACNA2D2,CBARP,CHRNA4,CLCN3,STOML1,CNR1,CNTN1,AKAP7,AKAP6,AKAP5,CRHBP,CRY2,NCOR1,CYBB,TCAF1,DAPK1,DBI,DMD,DMPK,SHANK1,DPP6,DPYSL2,EDN1,EDN3,EDNRA,ACSL4,PTK2B,FGF12,FGF14,FHL1,HVCN1,SARAF,OGA,GABBR1,INPP5K,GCK,PPARGC1A,GNAO1,MCHR1,GPER1,GRIN2D,IGF1,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNN2,KCNQ3,MEF2C,MYO5A,FXYD7,OPRL1,P2RX7,P2RY1,PDE4B,PDE4D,PDPK1,NLGN3,NALCN,PIK3C2A,FXYD1,NKAIN4,PRKCB,MAPK9,RELN,NKAIN1,RASGRF1,RASGRF2,KCNIP3,KCNIP1,SCN2B,SCN7A,SCN8A,SGK1,NLGN1,SLC8A1,SNCA,NKAIN2,PLCB1,ARC,TPCN2,LRRC8A,KCNE5,SGK3,P2RY12,KCNK12,KCNAB1,WNK3,WNK2,RTN4,NETO2,JPH3" GO: Biological Process GO:1902803 regulation of synaptic vesicle transport 2.31E-05 2.04E-01 1.45E-03 1.40E-02 15 36 "ATP2A2,SYNJ1,RIMS4,RIMS2,DNM1,FGF14,GRIK5,LRRK2,STX1B,NLGN1,NAPB,SNCA,STX1A,STXBP1,SYN1" GO: Biological Process GO:0010771 negative regulation of cell morphogenesis involved in differentiation 2.37E-05 2.10E-01 1.48E-03 1.43E-02 35 130 "SEMA6A,SEMA7A,SEMA4G,ARHGDIA,LDLRAD4,ARHGEF1,SLIT2,NGEF,AATK,SEMA3D,CDKL3,FGF13,MAD2L2,SEMA4D,CIT,LINGO1,MBP,NLGN3,SEMA5B,PPP3CA,PTK2,PTPRO,AP1AR,SALL1,SEMA6D,FUZ,NLGN1,SPP1,SPART,PBLD,KANK1,TTC3,GORASP1,SEMA3B,RTN4" GO: Biological Process GO:0014047 glutamate secretion 2.56E-05 2.26E-01 1.57E-03 1.52E-02 19 53 "ADORA1,ADORA2A,PPFIA4,PPFIA3,CCK,DPYSL2,GABBR1,CPLX1,GRM2,MYO6,NF1,NTRK2,P2RX7,SNAP25,SNCA,STX1A,STXBP1,SYT1,SLC17A7" GO: Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis 2.56E-05 2.27E-01 1.57E-03 1.52E-02 28 95 "SYT13,DOC2A,CADPS,ATP2A2,CACNA1I,CACNA1G,CACNA1A,CBARP,RIMS4,RIMS2,SYT3,SYT17,GRIK5,C2CD4C,KCNB1,SYTL4,SCAMP5,LRRK2,STX1B,NLGN1,NAPB,STX1A,STXBP1,PLCB1,SYN1,SYT1,SYT5,TRIM9" GO: Biological Process GO:0014829 vascular smooth muscle contraction 2.76E-05 2.44E-01 1.68E-03 1.62E-02 12 25 "AGT,BBS2,CACNA1G,DOCK4,EDN1,EDN3,EDNRA,EDNRB,PIK3C2A,RAP1GDS1,SMPD3,SLC8A1" GO: Biological Process GO:0010977 negative regulation of neuron projection development 2.79E-05 2.47E-01 1.68E-03 1.62E-02 39 152 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,RAB29,ARHGEF1,CBFA2T2,SLIT2,NGEF,MAP4K4,CRMP1,AATK,KIAA0319,SEMA3D,CDKL3,FGF13,SEMA4D,STMN2,CIT,LINGO1,RBPJ,MBP,NLGN3,SEMA5B,PMP22,PPP3CA,PTK2,PTPRG,PTPRO,SEMA6D,NLGN1,SPP1,SPART,KANK1,GORASP1,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0031345 negative regulation of cell projection organization 2.80E-05 2.47E-01 1.68E-03 1.62E-02 44 179 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,RAB29,ARHGEF1,CBFA2T2,EVI5L,SLIT2,NGEF,MAP4K4,CRMP1,AATK,ARHGAP24,KIAA0319,SEMA3D,CDKL3,FGF13,EVL,SEMA4D,STMN2,CIT,LINGO1,RBPJ,MAP4,MBP,NLGN3,SEMA5B,PMP22,PPP3CA,PTK2,PTPRG,PTPRO,CEP97,SEMA6D,NLGN1,SPP1,SPART,KANK1,GORASP1,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0051130 positive regulation of cellular component organization 2.93E-05 2.58E-01 1.74E-03 1.68E-02 216 1263 "ABR,ACHE,ADD1,AXIN2,ADRB2,AGT,KIAA1324,BIN1,OGT,DPP10,SEMA7A,C6orf89,APC,EPB41L5,APOC2,CPNE5,ARHGDIA,ARRB1,ARRB2,NUMB,DYNLL1,EIF4G3,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,SYNJ1,ARHGEF7,WASF1,KALRN,HAP1,CAMK2B,CBLN1,CCK,CBFA2T2,SEPT7,CDH2,NUMBL,CFL2,SLIT2,CPNE6,NRXN3,QKI,CNR1,PICK1,CNTN1,AKAP5,BAG4,SH2B1,NCOR1,GDA,CLIP3,ARHGEF10,SLITRK5,RIMS2,MYADM,TCAF1,HDAC4,TBC1D5,IST1,DBN1,DMD,SHANK1,DOCK2,DPP6,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EIF4G2,TENM1,PAN3,EPHB1,ERBB2,ERCC2,CDKL3,SIRPB1,PTK2B,RACK1,FCGR1A,FER,OLFM1,FGFR1,BAIAP2,MEX3B,EVL,SEMA4D,ANKFY1,SYT3,ZBED3,APOPT1,PRELID3A,STAU2,OGA,FYN,IQGAP2,SYT17,DISC1,SEPT9,GCNT2,ARFIP1,PPARGC1A,GPER1,STMN2,TPPP,GSN,HAS2,NCKAP1L,SYNPO,HNMT,NEGR1,HSPA1L,IRF8,IGF1,SCIN,LRRTM1,ITPKA,KCNB1,KCNN3,KIT,L1CAM,LIG4,LIMS1,PAXBP1,MAPT,MITF,NFE2L2,NTRK2,NTRK3,OPA1,OXTR,P2RX7,TREM2,PALM,ENPP2,PDPK1,ZDHHC8,NLGN3,PIK3R1,PLXNB1,MAGEL2,LRRN3,PPP3CC,MAPK3,MAPK9,RELN,BCAS3,PTK2,PTN,PTPRD,PTX3,RET,KCTD17,ROBO1,KIRREL1,ROBO2,FBXW7,ATAT1,CLIP1,AP1AR,FNIP1,SGK1,PPM1E,CPEB3,FUZ,AMBRA1,NLGN1,ABLIM3,SIRT2,TRIM67,SLC11A1,TET1,SNCA,CLASP2,CLSTN2,TTBK2,PHLDB1,PLCB1,SYT1,COBL,TACR1,MTCL1,MLST8,TAL1,ADGRL3,CUX2,CLASP1,SYNE1,OBSL1,CRTC1,TEK,SIRT1,TIAM1,BHLHB9,TLR4,PARD3,TP53BP2,TPM1,WBP2,LRRC24,TSC1,FLRT2,VLDLR,WIPF1,WNT7A,RICTOR,NDRG4,CRB2,SPIRE1,MFF,HPS4,WNK3,NELFE,ACTR3B" GO: Biological Process GO:0050807 regulation of synapse organization 2.93E-05 2.59E-01 1.74E-03 1.68E-02 34 126 "ADGRB1,ADGRB2,ADGRB3,CAMK2B,CBLN1,CDH2,NRXN3,SLITRK5,DBN1,DMPK,EPHB1,PDLIM5,STAU2,DISC1,PCDH17,LRRTM1,MEF2C,NTRK2,NTRK3,OXTR,NLGN3,LRRN3,RELN,PTK2,PTN,ROBO2,NLGN1,CLSTN2,ADGRL3,CUX2,BHLHB9,LRRC24,FLRT2,WNT7A" GO: Biological Process GO:1901880 negative regulation of protein depolymerization 2.97E-05 2.62E-01 1.75E-03 1.69E-02 22 67 "ADD1,ADD2,APC,SHROOM2,SPTBN4,ARHGEF2,APC2,FGF13,EVL,STMN2,GSN,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SPTAN1,SPTB,CLASP2,CLASP1,PLEKHH2" GO: Biological Process GO:0016482 cytosolic transport 3.30E-05 2.91E-01 1.93E-03 1.87E-02 133 720 "SYS1,AXIN2,AP2A1,TBC1D14,C1QTNF3,SYT13,DOC2A,AMPH,ANK2,RGS20,CADPS,STX16,ATP2A2,BARD1,BMP7,SYNJ1,MTMR2,RAB29,CACNA1A,CALM1,HAP1,CAPN3,SPAG9,AP4M1,CLTC,AKAP6,CABP1,AKAP5,BAG4,RIMS4,RIMS2,SNPH,TBC1D5,DBI,DCTN1,SGSM2,DMD,DNM1,DPYSL2,EDNRA,EGFR,STX2,RAB9B,ERBB4,APC2,DNAJC27,TLR7,PTK2B,RACK1,SEC24B,FGF14,VTI1B,ANKFY1,SYT3,ZBED3,PRELID3A,OGA,DENND2A,SYT17,CPLX2,CPLX1,WASHC2A,GPER1,PCLO,GRIK5,HNMT,HSPA1L,MYLK2,IGF1,C2CD4C,JAK2,KCNN3,IPO5,SYTL4,LYPLAL1,BLOC1S2,MXI1,MYO5A,NF1,OGG1,P2RX7,PDE4D,PDPK1,ZDHHC8,PIK3R1,PKD1,MAGEL2,PPM1B,PPP3CA,RANBP3L,PKIA,MAPK3,MAPK7,VPS13C,RDX,FBXW7,LRRK2,STX1B,AP1AR,KIF16B,NLGN1,ABLIM3,SLC8A1,NAPB,SNAP25,SNCA,ERC1,PBLD,STX1A,KANK1,SULF2,STXBP1,VPS13A,SYN1,SYT1,SYT5,FBXW11,TEK,SIRT1,AKTIP,THRA,TLR4,WIPF1,WNT7A,XPO1,ZIC1,TRIM9,EVI5,HPS4,NLRP3,AAAS,AP3B2,JPH3" GO: Biological Process GO:0032535 regulation of cellular component size 3.34E-05 2.95E-01 1.94E-03 1.87E-02 78 377 "ADD1,ADD2,SEMA6A,OGT,SEMA7A,SHROOM2,AQP6,SEMA4G,SPTBN4,ATP2B2,WASF1,CFL2,SLIT2,CLCN3,PICK1,BAG4,AATK,PLXNA4,MYADM,IST1,DBN1,DPYSL2,EDN1,SEMA3D,PLXNC1,EIF4G2,TENM1,CDKL3,PTK2B,FER,OLFM1,FGF13,BAIAP2,EVL,SEMA4D,IQGAP2,DISC1,ARFIP1,CIT,GSN,NCKAP1L,SCIN,L1CAM,MAPT,DBNL,NRCAM,NTRK3,P2RX7,TMOD2,SEMA5B,MAGEL2,RDX,RET,KIRREL1,AP1AR,SEMA6D,FHOD3,SLC12A2,SLC12A4,SPP1,SPTAN1,SPTB,SPART,CLASP2,KANK1,MLST8,LRRC8A,TSC1,TSC2,PLEKHH2,VAV1,WIPF1,WNT7A,RICTOR,SPIRE1,SEMA3B,RTN4,ACTR3B" GO: Cellular Component GO:0045202 synapse 5.08E-38 5.10E-35 5.10E-35 3.82E-34 254 870 "SYN3,ASIC1,ACHE,ACTN1,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,KCTD16,SPARCL1,SYT13,DOC2A,AMPH,BIN1,LRFN1,ANK2,PPFIA4,PKP4,APBA2,KCNAB2,APBB2,APC,BCAS1,PPFIA3,MADD,CASK,ARRB1,RGS20,ARRB2,CADPS,ATP1A1,ATP1A3,ATP2A2,ATP2B2,ATP6V1G2,ATP6V0A1,ADGRB1,ADGRB3,MPDZ,HCN2,SYNJ1,MTMR2,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CBLN1,CCK,P2RX6,SYNGR3,DGKI,ARHGEF2,SEPT7,CDH2,DCLK1,DLGAP2,DLGAP1,CBARP,CHN2,CHRNA4,NRXN3,CLCN3,CLTC,HOMER3,CNN3,PICK1,WHRN,CABP1,COL4A5,AKAP5,MYRIP,NECTIN3,SNCAIP,SIPA1L1,RIMS4,ERC2,RIMS2,ARHGAP32,SNPH,HDAC4,KCTD8,DBI,DBN1,SNAP91,SV2B,GRIN3A,DMD,DNM1,SHANK1,CPEB2,DPYSL2,DRP2,DTNA,DTNB,DNM1L,EGFR,COPS4,RGS17,ENO2,RASGRP2,GPHN,STX2,ERBB2,ERBB4,ADGRV1,NRN1,PTK2B,OLFM1,BAIAP2,VTI1B,SYT3,NBEA,PDLIM5,NSG1,BRSK1,FYN,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,DISC1,CPLX2,CPLX1,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SYNPO,CPT1C,SHISA6,ICA1,MYLK2,TMEM240,SLC6A17,LRRTM1,ITGA7,ITPKA,KCNB1,KCND2,KCNN2,KCNN3,STXBP5,L1CAM,LAMA2,SYTL4,MAP2,MAP4,MAPT,MEF2C,SCAMP5,GIT1,DBNL,MYO5A,MYO6,MYO7A,NEFH,NF1,NPY,NRCAM,NTRK2,P2RX7,P2RY1,PALM,PCDH8,PDE4B,PDPK1,NLGN3,SDK2,POLG,SH3KBP1,PPP3CA,MAPK10,NDUFS7,PTCH1,PTN,PTPRN,PTPRN2,PTPRO,IQSEC3,PRRT2,RGS12,PRIMA1,LRRK2,STX1B,CPEB3,SHC4,CNKSR2,NLGN1,SLC8A1,LGI3,CPEB4,ARFGAP1,SNAP25,SNCA,FAIM2,PDZRN3,PDZD2,NMNAT2,ERC1,DDN,SPART,CLSTN2,ZC4H2,STX1A,SEPT3,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,DNMBP,DMXL2,SYNE1,CRTC1,TIAM1,RIMBP2,PRRT1,RUSC1,FLRT2,WNT7A,TRIM9,ELFN1,ANKS1B,SLC30A3,MFF,CADM2,SLC17A7,FZD3,RTN4,FXR1,NETO2,NETO1" GO: Cellular Component GO:0097458 neuron part 5.28E-37 5.30E-34 2.65E-34 1.99E-33 377 1545 "SYN3,ACADM,ASIC1,ACHE,ACTN1,NDRG2,ADD1,ADD2,ADORA1,ADORA2A,UNC5A,ADRB2,KCTD16,SEMA6A,ALCAM,ALK,SYT13,BEGAIN,DOC2A,AMPH,BIN1,OGT,ANK2,PPFIA4,APBA2,KCNAB2,APBB2,APC,PPFIA3,CPNE5,SHROOM2,MADD,CASK,SPTBN4,ARRB1,ARRB2,CADPS,MARK4,NCOA1,ATP1A1,ATP1A3,ATP2B2,ATP6V1G2,ATP6V0A1,KIF1A,BBS2,MPDZ,RGS11,RGS9,HCN2,NRP2,PROM1,BMPR1B,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CAMK2G,CCK,P2RX6,SYNGR3,DGKI,ARHGEF2,SEPT7,CDH2,DCLK1,DLGAP2,DLGAP1,CBARP,PLEKHB1,CHRNA4,TAOK2,CPNE6,NRXN3,CLCN3,CLTC,NGEF,CNGA3,CNN3,CNR1,PICK1,WHRN,AKAP5,SLC4A8,MYRIP,ZNF385A,CRHBP,CRMP1,AATK,SNCAIP,CSNK1E,SIPA1L1,RIMS4,CNTNAP2,CST3,ERC2,RIMS2,CYBB,BOC,DOCK4,ARHGAP32,RIPOR2,SNPH,KCTD8,DBI,DBN1,TIAM2,SNAP91,SACS,PARD6A,SV2B,GRIN3A,RAB39B,DMD,DNM1,SHANK1,CPEB2,SLC12A6,DPP6,DPYSL2,DRP2,DTNA,DNM1L,SEZ6L2,EIF4G2,COPS4,TNK2,RGS17,ENO2,RASGRP2,EPHB1,GPHN,STX2,ADGRV1,ACSL4,PTK2B,TUBB3,RACK1,PPP1R1B,OLFM1,FGF13,BAIAP2,VTI1B,SYNCRIP,PSD2,SYT3,DCTN2,PDLIM5,STAU2,BRSK1,GABBR1,CHL1,GABRB3,GABRG2,GAD1,SYT17,DISC1,INPP5K,CPLX2,CPLX1,GHR,PPARGC1A,NTNG2,CRCP,GLUL,GNAO1,GPER1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM2,GRM8,CIT,FAM107A,ELOVL5,ACOT7,SYNPO,HNMT,NEGR1,CPT1C,AGFG1,ICA1,MYLK2,IGF1,KNDC1,IL6R,IL6ST,SLC6A17,LRRTM1,ITPKA,KCNB1,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,STXBP5,L1CAM,LAMA2,STMN1,SYTL4,PACRG,ZFYVE27,MAP2,MAP4,MAPT,AQP11,MBP,SCAMP5,GIT1,DBNL,BLOC1S2,ADAM22,MYO5A,MYO6,MYO7A,NCAM2,NEFM,NEFH,NELL2,NF1,NPY,NPTX1,NRCAM,NTRK2,OCRL,OPA1,OPRL1,P2RX7,P2RY1,PALM,PCDH8,PCDH9,PDE1C,PDE4B,PDE1B,PDPK1,TMOD2,NLGN3,PIK3R1,STRN3,POLG,SH3KBP1,DRAM2,NKAIN4,PPP5C,SKOR1,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPN13,PTPRN,PTPRN2,PTPRO,STRC,QDPR,RASGRF1,RDX,CRTAC1,RET,RGS12,ROBO1,KIRREL1,ROBO2,LRRK2,ATAT1,KCNIP3,KCNIP1,RXRA,STX1B,S100B,SCN8A,SGK1,CPEB3,CNKSR2,NLGN1,SLC6A11,SLC8A1,SIRT2,LGI3,CPEB4,ARFGAP1,SMARCA4,SMARCC2,SMARCD3,SNAP25,SNCA,PDZD2,NMNAT2,MYCBP2,ERC1,SPTAN1,DDN,NFASC,CLASP2,CLSTN2,SST,SSTR1,SSTR2,STAU1,STX1A,SEPT3,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,COBL,SYT5,TACR1,EXOC7,ADGRL3,DMXL2,PCDHGB1,SYNE1,PUM2,CRTC1,DICER1,SIRT1,TIAM1,PARD3,TRPM2,TSC1,TSC2,UCHL1,OSBP2,FLRT2,VGF,RBFOX3,CLIP2,WNT7A,WRN,KLC2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,SLC30A3,MAP3K12,MFF,CADM2,SLC38A1,GDPD5,SLC17A7,KCNAB1,FZD3,RTN4,HNRNPA3,SNX14,FXR1,IFT88,DPF3,AP3B2" GO: Cellular Component GO:0043005 neuron projection 3.28E-31 3.29E-28 1.10E-28 8.23E-28 299 1194 "ACADM,ASIC1,ACHE,ACTN1,NDRG2,ADD1,ADORA1,ADORA2A,UNC5A,ADRB2,SEMA6A,ALCAM,ALK,BEGAIN,DOC2A,AMPH,BIN1,OGT,ANK2,KCNAB2,APBB2,APC,CPNE5,CASK,SPTBN4,ARRB1,ARRB2,MARK4,NCOA1,ATP1A3,ATP2B2,ATP6V0A1,KIF1A,MPDZ,RGS11,HCN2,NRP2,BMPR1B,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,CACNA1G,CACNA1A,CACNA1B,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CCK,P2RX6,DGKI,ARHGEF2,SEPT7,CDH2,DLGAP2,CBARP,CHRNA4,TAOK2,CPNE6,CLCN3,CLTC,NGEF,CNGA3,CNN3,CNR1,PICK1,WHRN,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,AATK,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,RIMS2,CYBB,BOC,ARHGAP32,SNPH,DBN1,TIAM2,SNAP91,SACS,PARD6A,SV2B,GRIN3A,RAB39B,DMD,DNM1,SHANK1,CPEB2,SLC12A6,DPYSL2,DRP2,DTNA,EIF4G2,TNK2,RGS17,ENO2,RASGRP2,EPHB1,GPHN,PTK2B,TUBB3,RACK1,OLFM1,FGF13,BAIAP2,SYNCRIP,PSD2,DCTN2,PDLIM5,STAU2,GABBR1,CHL1,GABRB3,GABRG2,GAD1,DISC1,INPP5K,CPLX2,CPLX1,PPARGC1A,NTNG2,CRCP,GLUL,GNAO1,GPER1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM2,GRM8,FAM107A,ELOVL5,ACOT7,SYNPO,HNMT,NEGR1,CPT1C,ICA1,MYLK2,KNDC1,IL6ST,LRRTM1,ITPKA,KCNB1,KCND1,KCND2,KCNN2,KCNN3,KCNQ3,KIF5A,L1CAM,LAMA2,STMN1,PACRG,ZFYVE27,MAP2,MAP4,MAPT,AQP11,MBP,GIT1,DBNL,BLOC1S2,ADAM22,MYO5A,MYO6,NCAM2,NEFM,NEFH,NELL2,NF1,NPY,NPTX1,NRCAM,NTRK2,OPA1,OPRL1,P2RY1,PALM,PCDH8,PCDH9,PDE4B,TMOD2,NLGN3,PIK3R1,STRN3,POLG,SH3KBP1,PPP5C,SKOR1,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPN13,PTPRN,PTPRN2,PTPRO,QDPR,RASGRF1,CRTAC1,RET,RGS12,ROBO1,KIRREL1,ROBO2,LRRK2,ATAT1,KCNIP3,KCNIP1,RXRA,SCN8A,SGK1,CPEB3,CNKSR2,NLGN1,SLC6A11,SLC8A1,SIRT2,LGI3,CPEB4,SNAP25,SNCA,PDZD2,MYCBP2,SPTAN1,DDN,NFASC,CLASP2,SSTR1,SSTR2,STAU1,STX1A,SEPT3,STXBP1,SYN1,ARC,SYN2,SYP,SYT1,COBL,SYT5,TACR1,EXOC7,ADGRL3,PCDHGB1,SYNE1,PUM2,CRTC1,DICER1,SIRT1,TIAM1,PARD3,TRPM2,TSC1,TSC2,UCHL1,OSBP2,FLRT2,VGF,CLIP2,WRN,KLC2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,SLC30A3,MAP3K12,CADM2,SLC38A1,GDPD5,SLC17A7,KCNAB1,FZD3,RTN4,HNRNPA3,SNX14,FXR1,AP3B2" GO: Cellular Component GO:0044456 synapse part 4.42E-31 4.44E-28 1.11E-28 8.31E-28 207 708 "SYN3,ASIC1,ACHE,ACTN1,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,KCTD16,SYT13,DOC2A,AMPH,BIN1,LRFN1,ANK2,PPFIA4,PKP4,APBA2,KCNAB2,BCAS1,PPFIA3,MADD,CASK,ARRB1,RGS20,ARRB2,CADPS,ATP1A1,ATP1A3,ATP6V1G2,ATP6V0A1,ADGRB1,ADGRB3,MPDZ,SYNJ1,MTMR2,BAIAP3,CACNA1A,CACNA1B,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CBLN1,CCK,P2RX6,SYNGR3,DGKI,ARHGEF2,CDH2,DCLK1,DLGAP2,DLGAP1,CBARP,CHRNA4,NRXN3,CLCN3,CLTC,HOMER3,CNN3,PICK1,CABP1,AKAP5,NECTIN3,SNCAIP,SIPA1L1,RIMS4,ERC2,RIMS2,ARHGAP32,SNPH,KCTD8,DBI,DBN1,SNAP91,SV2B,GRIN3A,DMD,DNM1,SHANK1,DPYSL2,DRP2,DNM1L,COPS4,ENO2,GPHN,STX2,ERBB2,ERBB4,PTK2B,OLFM1,BAIAP2,VTI1B,SYT3,NBEA,PDLIM5,NSG1,BRSK1,FYN,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,SYT17,DISC1,CPLX2,CPLX1,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SYNPO,ICA1,MYLK2,TMEM240,SLC6A17,LRRTM1,ITPKA,KCNB1,KCND2,KCNN2,STXBP5,L1CAM,LAMA2,SYTL4,MAP2,MAP4,MAPT,MEF2C,SCAMP5,DBNL,MYO5A,NEFH,NF1,NPY,NTRK2,P2RX7,P2RY1,PALM,PCDH8,PDE4B,PDPK1,NLGN3,POLG,PPP3CA,MAPK10,NDUFS7,PTCH1,PTPRN,PTPRN2,PTPRO,IQSEC3,LRRK2,STX1B,SHC4,CNKSR2,NLGN1,SLC8A1,LGI3,CPEB4,ARFGAP1,SNAP25,SNCA,FAIM2,PDZD2,ERC1,DDN,CLSTN2,ZC4H2,STX1A,SEPT3,STXBP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,SYNE1,TIAM1,RUSC1,WNT7A,TRIM9,ANKS1B,SLC30A3,MFF,SLC17A7,FZD3,RTN4,FXR1,NETO2,NETO1" GO: Cellular Component GO:0044463 cell projection part 3.09E-24 3.10E-21 6.21E-22 4.65E-21 270 1139 "SYN3,ASIC1,ACTN1,NDRG2,ADCY6,ADD1,ADD2,FZD9,ADORA1,ADORA2A,UNC5A,ADRB2,AP2A1,WDR35,CC2D2A,AK2,CEP126,AMPH,BIN1,FGD2,KCNAB2,APBB2,APC,EPB41L5,CASK,SPTBN4,ARRB1,ARRB2,DNAH17,MARK4,DYNLL1,ATP1A1,ATP1A3,ATP6V0A1,KIF1A,BBS2,RGS11,RGS9,HCN2,PROM1,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,CA4,CACNA1B,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CAMK2G,CCK,P2RX6,SCARB1,ENTPD2,DGKI,ARHGEF2,SEPT7,DCLK1,DLGAP1,CBARP,RAB28,CLCN3,CLTB,CLTC,NGEF,CCDC151,CNGA3,CNN3,CNR1,PICK1,WHRN,AKAP5,RTTN,CRHBP,AATK,CSNK1E,OSBPL3,SIPA1L1,CNTNAP2,ERC2,ARHGEF4,BOC,ARHGAP32,RIPOR2,KIAA0586,AIF1L,DNAL1,DBN1,TIAM2,SNAP91,PARD6A,SV2B,KIF19,DMD,DNM1,DNAH9,SHANK1,DPYSL2,WDPCP,PLEKHA1,TNK2,MFSD10,RASGRP2,EPHB1,APC2,ADGRV1,SH3YL1,PTK2B,DLC1,OLFM1,FGF13,BAIAP2,SYNCRIP,DCTN2,AKAP3,TMEM107,AK8,STAU2,GABBR1,GABRB3,GABRG2,GAD1,DISC1,SEPT9,INPP5K,CPLX2,CPLX1,GLI2,GLUL,FERMT2,MCHR1,GPER1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,BVES,RABL2A,PACSIN2,SYNPO,CFAP126,MYLK2,LRRTM1,ITPKA,KCNB1,KCND2,KCNN2,KCNQ3,KIF2A,KIF5A,L1CAM,LAMA2,PACRG,ZFYVE27,MAP2,MAP4,MAPT,MBP,POC1B,BLOC1S2,MYO5A,MYO6,MYO7A,NEFH,NPY,SLC11A2,NRCAM,NTRK2,OPA1,P2RY1,PALM,PCDH9,PDE4A,PDE4B,PDPK1,TMOD2,ABCB1,PKD1,SEPT4,POLG,PPP5C,PRKACB,CEP41,PRKAR1B,PRKCB,MAPK10,HYDIN,PRPH,PTCH1,PTH1R,PTPRN,PTPRN2,PTPRO,STRC,TMEM231,CCDC40,RASGRF1,CRTAC1,KIF7,ROBO1,KIRREL1,ROBO2,LRRK2,KCNIP3,SCN8A,FERMT1,AMBRA1,CNKSR2,NLGN1,DZIP1,SLC8A1,SIRT2,ARFGAP1,IFT122,SNAP25,SNCA,SPATA7,SPTAN1,DDN,NFASC,CLASP2,CLSTN2,TTBK2,KANK1,STXBP1,SYNE2,SYN1,ARC,SYN2,SYP,SYT1,COBL,EXOC7,RPGRIP1L,PCDHGB1,SYNE1,DNAH7,DICER1,SIRT1,GPR161,TIAM1,PARD3,TPM1,TSC1,TSC2,UCHL1,CLIP2,KLC2,NDRG4,TMEM237,ANKS1B,LAMP5,MAP3K12,DNALI1,GDPD5,KCNAB1,DNAH10,FZD3,RTN4,FXR1,IFT88,AP3B2,SPATA13" GO: Cellular Component GO:0036477 somatodendritic compartment 1.54E-21 1.55E-18 2.59E-19 1.94E-18 214 867 "ASIC1,ACHE,ACTN1,ADD1,ADORA1,ADORA2A,UNC5A,ADRB2,ALCAM,BEGAIN,OGT,APC,CPNE5,SHROOM2,CASK,SPTBN4,ARRB1,ARRB2,ATP1A3,ATP2B2,KIF1A,MPDZ,RGS11,HCN2,BMPR1B,ARHGEF7,MTMR2,SGCE,CACNA1G,CACNA1A,CACNA1B,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CCK,P2RX6,DGKI,ARHGEF2,CDH2,DLGAP2,CHRNA4,TAOK2,CPNE6,CNGA3,CNN3,PICK1,WHRN,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SNCAIP,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CYBB,BOC,ARHGAP32,SNPH,DBN1,SACS,PARD6A,GRIN3A,SHANK1,DPP6,DPYSL2,DRP2,SEZ6L2,TNK2,ENO2,EPHB1,GPHN,ACSL4,PTK2B,TUBB3,RACK1,PPP1R1B,OLFM1,FGF13,BAIAP2,VTI1B,SYNCRIP,PSD2,STAU2,GABBR1,CHL1,CPLX2,CPLX1,GHR,PPARGC1A,CRCP,GLUL,GNAO1,GPER1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM2,GRM8,CIT,ELOVL5,SYNPO,NEGR1,CPT1C,AGFG1,ICA1,MYLK2,IGF1,KNDC1,IL6R,IL6ST,ITPKA,KCNB1,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,L1CAM,LAMA2,ZFYVE27,MAP2,MAPT,AQP11,MBP,DBNL,MYO5A,MYO6,NEFH,NELL2,NF1,NPY,NTRK2,OPA1,P2RX7,P2RY1,PALM,PCDH8,PDE1C,PDE4B,PDE1B,PDPK1,NLGN3,STRN3,PPP5C,SKOR1,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPRN,PTPRO,RASGRF1,RET,RGS12,ROBO1,KIRREL1,LRRK2,KCNIP3,KCNIP1,S100B,SCN8A,CPEB3,CNKSR2,NLGN1,SLC8A1,SIRT2,CPEB4,SNAP25,DDN,SST,STAU1,SYN1,ARC,COBL,SYT5,TACR1,SYNE1,PUM2,CRTC1,DICER1,TIAM1,PARD3,TRPM2,TSC2,UCHL1,OSBP2,VGF,RBFOX3,CLIP2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,CADM2,GDPD5,KCNAB1,FZD3,RTN4,SNX14,FXR1" GO: Cellular Component GO:0060076 excitatory synapse 3.78E-19 3.79E-16 5.42E-17 4.06E-16 88 252 "SYN3,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN1,PKP4,KCNAB2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,MTMR2,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,ARHGAP32,DBN1,SNAP91,GRIN3A,SHANK1,DRP2,ERBB4,PTK2B,BAIAP2,PDLIM5,FYN,DISC1,GPER1,PCLO,GRIA2,GRIK5,GRIN2C,SYNPO,MYLK2,LRRTM1,KCND2,MAP2,MAP4,MAPT,DBNL,NEFH,NF1,NTRK2,P2RY1,PALM,PDE4B,PDPK1,NLGN3,MAPK10,PTCH1,STX1B,CNKSR2,NLGN1,CPEB4,ARFGAP1,PDZD2,CLSTN2,SYN1,ARC,SYN2,SYP,SYT1,RUSC1,ELFN1,ANKS1B,SLC17A7,RTN4,NETO2,NETO1" GO: Cellular Component GO:0098793 presynapse 1.70E-18 1.71E-15 2.13E-16 1.60E-15 106 341 "SYN3,ACHE,ADORA1,ADORA2A,KCTD16,SYT13,DOC2A,AMPH,BIN1,PPFIA4,APBA2,PPFIA3,MADD,CASK,CADPS,ATP6V1G2,ATP6V0A1,SYNJ1,MTMR2,BAIAP3,CACNA1A,CACNA1B,CALB1,CALB2,HAP1,CAMK2A,CCK,SYNGR3,DGKI,CDH2,CBARP,NRXN3,CLCN3,CLTC,PICK1,SNCAIP,RIMS4,ERC2,RIMS2,SNPH,KCTD8,DBI,SNAP91,SV2B,DNM1,DPYSL2,DNM1L,COPS4,STX2,VTI1B,SYT3,BRSK1,GABBR1,GABRB3,GAD1,SYT17,DISC1,CPLX2,CPLX1,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRM2,GRM8,ICA1,MYLK2,SLC6A17,STXBP5,L1CAM,SYTL4,SCAMP5,MYO5A,NF1,NPY,NTRK2,P2RX7,PCDH8,PDE4B,POLG,PTPRN,PTPRN2,LRRK2,STX1B,NLGN1,LGI3,SNAP25,SNCA,ERC1,STX1A,SEPT3,STXBP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,WNT7A,TRIM9,SLC30A3,MFF,SLC17A7,FZD3" GO: Cellular Component GO:0098794 postsynapse 4.20E-18 4.22E-15 4.69E-16 3.51E-15 127 449 "SYN3,ASIC1,ACHE,ACTN1,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,KCTD16,LRFN1,ANK2,PKP4,KCNAB2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ATP1A3,ADGRB1,ADGRB3,MPDZ,MTMR2,KALRN,CAMK2A,CAMK2B,CAMK2G,CBLN1,P2RX6,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,CHRNA4,HOMER3,CNN3,PICK1,CABP1,AKAP5,NECTIN3,SIPA1L1,ERC2,ARHGAP32,KCTD8,DBN1,SNAP91,GRIN3A,DMD,SHANK1,DRP2,GPHN,ERBB2,ERBB4,PTK2B,BAIAP2,NBEA,PDLIM5,NSG1,FYN,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,DISC1,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,SYNPO,MYLK2,LRRTM1,ITPKA,KCNB1,KCND2,KCNN2,LAMA2,MAP2,MAP4,MAPT,MEF2C,DBNL,NEFH,NF1,NTRK2,P2RY1,PALM,PCDH8,PDE4B,PDPK1,NLGN3,PPP3CA,MAPK10,PTCH1,PTPRO,IQSEC3,LRRK2,SHC4,CNKSR2,NLGN1,SLC8A1,CPEB4,ARFGAP1,SNCA,FAIM2,PDZD2,CLSTN2,ZC4H2,SYN1,ARC,SYN2,SYNE1,TIAM1,RUSC1,ANKS1B,SLC17A7,RTN4,FXR1,NETO2,NETO1" GO: Cellular Component GO:0014069 postsynaptic density 9.97E-18 1.00E-14 9.11E-16 6.82E-15 81 232 "SYN3,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN1,PKP4,KCNAB2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,MTMR2,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,ARHGAP32,DBN1,SNAP91,GRIN3A,SHANK1,DRP2,ERBB4,PTK2B,BAIAP2,PDLIM5,FYN,DISC1,GPER1,PCLO,GRIA2,GRIK5,GRIN2C,SYNPO,MYLK2,KCND2,MAP2,MAP4,MAPT,DBNL,NEFH,NF1,NTRK2,P2RY1,PALM,PDE4B,PDPK1,MAPK10,PTCH1,CNKSR2,NLGN1,CPEB4,ARFGAP1,PDZD2,CLSTN2,SYN1,ARC,SYN2,RUSC1,ANKS1B,RTN4,NETO2,NETO1" GO: Cellular Component GO:0099572 postsynaptic specialization 9.97E-18 1.00E-14 9.11E-16 6.82E-15 81 232 "SYN3,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,LRFN1,PKP4,KCNAB2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,MTMR2,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,ARHGAP32,DBN1,SNAP91,GRIN3A,SHANK1,DRP2,ERBB4,PTK2B,BAIAP2,PDLIM5,FYN,DISC1,GPER1,PCLO,GRIA2,GRIK5,GRIN2C,SYNPO,MYLK2,KCND2,MAP2,MAP4,MAPT,DBNL,NEFH,NF1,NTRK2,P2RY1,PALM,PDE4B,PDPK1,MAPK10,PTCH1,CNKSR2,NLGN1,CPEB4,ARFGAP1,PDZD2,CLSTN2,SYN1,ARC,SYN2,RUSC1,ANKS1B,RTN4,NETO2,NETO1" GO: Cellular Component GO:0043025 neuronal cell body 2.83E-16 2.85E-13 2.37E-14 1.78E-13 154 616 "ACHE,ADORA1,ADORA2A,UNC5A,ADRB2,ALCAM,BEGAIN,OGT,APC,CPNE5,SHROOM2,SPTBN4,ATP2B2,KIF1A,HCN2,BMPR1B,ARHGEF7,CACNA1G,CACNA1A,CACNA1B,CALB1,KALRN,PTBP2,CAMK2A,CAMK2B,CCK,P2RX6,DGKI,ARHGEF2,CHRNA4,CPNE6,CNGA3,CNN3,WHRN,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SNCAIP,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CYBB,BOC,SNPH,DBN1,PARD6A,GRIN3A,DPP6,DPYSL2,DRP2,SEZ6L2,TNK2,ENO2,GPHN,ACSL4,PTK2B,TUBB3,RACK1,PPP1R1B,OLFM1,BAIAP2,VTI1B,SYNCRIP,PSD2,STAU2,GABBR1,CPLX2,CPLX1,GHR,PPARGC1A,CRCP,GLUL,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM8,CIT,ELOVL5,SYNPO,NEGR1,AGFG1,MYLK2,IGF1,KNDC1,IL6R,IL6ST,KCNB1,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,L1CAM,MAP2,MBP,MYO5A,MYO6,NEFH,NELL2,NPY,NTRK2,P2RX7,PDE1C,PDE1B,PDPK1,NLGN3,STRN3,PPP5C,SKOR1,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTPRN,RASGRF1,RET,RGS12,ROBO1,LRRK2,KCNIP1,S100B,SCN8A,CNKSR2,SIRT2,SNAP25,DDN,SST,STAU1,COBL,SYT5,PUM2,CRTC1,TIAM1,PARD3,TRPM2,TSC2,UCHL1,VGF,RBFOX3,DPYSL5,CADM2,GDPD5,KCNAB1,FZD3,RTN4" GO: Cellular Component GO:0030425 dendrite 3.46E-16 3.48E-13 2.68E-14 2.01E-13 149 590 "ASIC1,ACHE,ACTN1,ADD1,ADORA1,ADORA2A,ADRB2,ALCAM,BEGAIN,APC,CASK,ARRB1,ARRB2,ATP1A3,ATP2B2,MPDZ,RGS11,HCN2,BMPR1B,MTMR2,SGCE,CACNA1G,CACNA1A,CACNA1B,CALB1,HAP1,CAMK2A,CAMK2B,CCK,P2RX6,DGKI,ARHGEF2,CDH2,DLGAP2,CHRNA4,TAOK2,CPNE6,CNGA3,CNN3,PICK1,WHRN,AKAP5,ZNF385A,CRHBP,CRMP1,SIPA1L1,CNTNAP2,CYBB,ARHGAP32,DBN1,SACS,SHANK1,DPYSL2,DRP2,TNK2,EPHB1,GPHN,PTK2B,TUBB3,RACK1,FGF13,BAIAP2,SYNCRIP,PSD2,STAU2,GABBR1,CHL1,CPLX2,CPLX1,PPARGC1A,CRCP,GNAO1,GPER1,PCLO,GRIA2,GRIK4,GRIK5,GRM2,ELOVL5,SYNPO,NEGR1,CPT1C,ICA1,MYLK2,KNDC1,IL6ST,ITPKA,KCNB1,KCND1,KCND2,KCNN2,KCNQ3,L1CAM,LAMA2,ZFYVE27,MAP2,MAPT,AQP11,DBNL,NELL2,NF1,NTRK2,OPA1,P2RY1,PALM,PCDH8,PDE4B,NLGN3,STRN3,PPP5C,SKOR1,RELN,PTCH1,PTPRO,RASGRF1,RET,RGS12,KIRREL1,LRRK2,KCNIP3,KCNIP1,SCN8A,CPEB3,NLGN1,SLC8A1,CPEB4,DDN,STAU1,SYN1,ARC,COBL,TACR1,SYNE1,PUM2,CRTC1,DICER1,TIAM1,TSC2,OSBP2,CLIP2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,KCNAB1,FZD3,SNX14,FXR1" GO: Cellular Component GO:0044297 cell body 4.47E-16 4.49E-13 3.21E-14 2.40E-13 167 691 "ACHE,ADORA1,ADORA2A,UNC5A,ADRB2,ALCAM,ALK,BEGAIN,OGT,APC,CPNE5,SHROOM2,SPTBN4,ATP2B2,KIF1A,HCN2,BMPR1B,ARHGEF7,CACNA1G,CACNA1A,CACNA1B,CALB1,KALRN,PTBP2,CAMK2A,CAMK2B,CCK,P2RX6,ENTPD2,DGKI,ARHGEF2,SEPT7,CHRNA4,CPNE6,CNGA3,CNN3,WHRN,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SNCAIP,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CYBB,BOC,SNPH,DBN1,PARD6A,GRIN3A,DPP6,DPYSL2,DRP2,SEZ6L2,TNK2,ENO2,GPHN,ACSL4,PTK2B,TUBB3,RACK1,PPP1R1B,OLFM1,BAIAP2,VTI1B,SYNCRIP,PSD2,STAU2,GABBR1,DISC1,CPLX2,CPLX1,GHR,PPARGC1A,CRCP,GLUL,GNAO1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM8,CIT,ELOVL5,ACOT7,SYNPO,NEGR1,AGFG1,HSPA1L,MYLK2,IGF1,KNDC1,IL6R,IL6ST,KCNB1,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,L1CAM,PACRG,MAP2,MAPT,MBP,MYO5A,MYO6,NEFH,NELL2,NPY,NTRK2,P2RX7,P2RY1,PDE1C,PDE1B,PDPK1,NLGN3,STRN3,PPP5C,SKOR1,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTPN13,PTPRN,RASGRF1,RET,RGS12,ROBO1,LRRK2,KCNIP1,S100B,SCN8A,CNKSR2,SIRT2,SNAP25,USP33,DDN,SST,STAU1,COBL,SYT5,TACR1,PUM2,CRTC1,TIAM1,PARD3,TRPM2,TSC2,UCHL1,VGF,RBFOX3,DPYSL5,CADM2,GDPD5,KCNAB1,FZD3,RTN4" GO: Cellular Component GO:0030424 axon 3.67E-15 3.69E-12 2.46E-13 1.84E-12 142 567 "ACADM,ACHE,ADORA1,ADORA2A,ADRB2,SEMA6A,ALCAM,ALK,AMPH,BIN1,KCNAB2,APC,SPTBN4,ATP1A3,ATP6V0A1,KIF1A,HCN2,NRP2,DST,SYNJ1,SYNJ2,MTMR2,CACNA1B,CALB1,CALB2,HAP1,CAMK2A,CCK,DGKI,SEPT7,CPNE6,CLCN3,CLTC,CNR1,WHRN,CRHBP,AATK,CNTNAP2,CST3,ERC2,BOC,DBN1,SNAP91,SACS,PARD6A,SV2B,DNM1,SLC12A6,DPYSL2,DTNA,EIF4G2,TNK2,EPHB1,PTK2B,TUBB3,OLFM1,FGF13,STAU2,GABBR1,GABRB3,GABRG2,GAD1,DISC1,CPLX2,CPLX1,NTNG2,CRCP,GLUL,GPER1,PCLO,STMN2,GRIA2,GRIK4,GRIK5,GRM2,SYNPO,CPT1C,MYLK2,LRRTM1,KCNB1,KCNQ3,KIF5A,L1CAM,ZFYVE27,MAPT,MBP,BLOC1S2,ADAM22,MYO5A,MYO6,NCAM2,NEFM,NEFH,NF1,NPY,NRCAM,NTRK2,OPA1,PALM,POLG,PRPH,RELN,PTCH1,PTPRN,PTPRN2,PTPRO,RET,ROBO1,ROBO2,LRRK2,ATAT1,KCNIP3,RXRA,SCN8A,SIRT2,SNAP25,SNCA,MYCBP2,SPTAN1,NFASC,CLASP2,STXBP1,SYN1,SYN2,SYP,SYT1,COBL,ADGRL3,DICER1,SIRT1,TIAM1,PARD3,UCHL1,MAP3K12,CADM2,SLC38A1,GDPD5,SLC17A7,KCNAB1,FZD3,FXR1,AP3B2" GO: Cellular Component GO:0097060 synaptic membrane 4.06E-14 4.08E-11 2.55E-12 1.91E-11 88 298 "ACHE,ADORA1,ADORA2A,LRFN2,KCTD16,LRFN1,ANK2,CASK,ARRB1,ARRB2,MPDZ,SYNJ1,MTMR2,CAMK2A,CBLN1,DGKI,DLGAP2,DLGAP1,CHRNA4,HOMER3,PICK1,CABP1,AKAP5,NECTIN3,SNCAIP,SIPA1L1,RIMS4,ERC2,RIMS2,ARHGAP32,SNPH,KCTD8,DBN1,SNAP91,GRIN3A,DMD,SHANK1,DRP2,ENO2,GPHN,ERBB2,OLFM1,NBEA,PDLIM5,NSG1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,DISC1,GPER1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SYNPO,TMEM240,LRRTM1,KCNB1,KCND2,L1CAM,NTRK2,P2RY1,PALM,PCDH8,NDUFS7,IQSEC3,SHC4,CNKSR2,NLGN1,SNAP25,FAIM2,ERC1,DDN,CLSTN2,ZC4H2,SEPT3,ARC,SYP,SYT1,SYNE1,RUSC1,ANKS1B,NETO1" GO: Cellular Component GO:0030054 cell junction 3.77E-12 3.79E-09 2.23E-10 1.67E-09 239 1200 "SYN3,ACHE,ACTN1,ADD1,ADRA1B,LRFN2,KCTD16,ALCAM,DOC2A,AMPH,LRFN1,CDC42BPA,ANK2,PKP4,KCNAB2,APC,EPB41L5,SHROOM2,PRX,CASK,SPTBN4,CADPS,NUMB,ATP1A1,STX16,ATP2A2,ATP2B2,SLC2A11,ADAM15,ADGRB1,MPDZ,DST,ARHGEF7,WASF1,CALB2,HAP1,CAMK2A,CBLN1,CLDN10,KRIT1,P2RX6,SYNGR3,ARHGEF2,CDH2,MAGI1,DLGAP2,DLGAP1,CBARP,CHRNA4,ARHGAP22,CLTC,HOMER3,CNN3,ARHGEF6,PICK1,AKAP6,CABP1,NECTIN3,CDC42BPB,AKAP12,SIPA1L1,RIMS4,ERC2,RIMS2,MYADM,ARHGAP32,SNPH,ARHGAP24,KCTD8,AIF1L,GIT2,DBN1,PARD6A,SV2B,GRIN3A,DMD,CD99L2,SHANK1,DRP2,PDCD6IP,DTNA,DNM1L,EGFR,COPS4,TNK2,RGS17,C8orf37,EPB41,EPB41L2,RASGRP2,GPHN,STX2,NRN1,PTK2B,DLC1,FER,OLFM1,FGF13,FGFR3,AMOTL2,FHL1,EVL,FLNC,FLT1,NBEA,PDLIM5,BRSK1,FYB1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,DISC1,IGSF5,FERMT2,GPER1,PCLO,GRIA2,PARD3B,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GSN,BVES,PACSIN2,SYNPO,CPT1C,ICA1,TJAP1,TMEM240,SLC6A17,LRRTM1,ITGA7,KCNB1,KCND2,KIFC3,KIT,STXBP5,L1CAM,LIG4,LIMS1,SCAMP5,AFDN,GIT1,DBNL,LAYN,CLDN11,OXTR,P2RX7,PCDHGC3,PCDH8,PCDH9,PDPK1,ABCB1,NLGN3,PIK3R1,ZFYVE21,PLEC,PMP22,SDK2,EPB41L4B,SH3KBP1,CEP41,MAPK3,LAMA1,PTK2,PTPRN,PTPRN2,RDX,PRRT2,RGS12,PRIMA1,KIRREL1,LRRK2,ATAT1,PUF60,FERMT1,ASAP3,SHC4,NLGN1,LIMS2,SLC8A1,SIRT2,LGI3,CDK5RAP2,SNAP25,SNCA,FAIM2,USP33,PDZD2,ARHGAP26,SPTAN1,NFASC,CLASP2,ZC4H2,ERBIN,MPRIP,CEP68,STX1A,SEPT3,SYNE2,SYN1,ARC,SYN2,SYP,SYT1,SYT5,DNMBP,PDLIM2,ADGRL3,DMXL2,RPGRIP1L,CLASP1,OBSL1,TNS2,TEK,TIAM1,RIMBP2,PRRT1,PARD3,TNS1,SYNPO2,RUSC1,FLRT2,VAV1,XRCC4,TRIM9,ANKS1B,SLC30A3,MFF,CADM2,SLC17A7,WNK3,GJC2,FRMD6,NETO1" GO: Cellular Component GO:0098589 membrane region 5.50E-12 5.53E-09 3.07E-10 2.30E-09 249 1267 "ACHE,ADCY5,ADCY6,FZD9,ADORA1,ADORA2A,UNC5A,LRFN2,ADRB2,AP2A1,AP2A2,KCTD16,LRFN1,ANK2,FGD2,APC,EPB41L5,SHROOM2,AQP6,CASK,ARRB1,ARRB2,NUMB,ATP1A1,SLC4A4,ATP1B3,ATP2B2,RIPK1,BBS2,MPDZ,RGS9,HCN2,CFLAR,PROM1,DST,SYNJ1,SYNJ2,BTK,MTMR2,SGCE,CA4,DDR1,CAMK2A,HIP1R,CBLN1,SCARB1,ENTPD2,DGKI,ARHGEF2,SEPT7,CDH2,DLGAP2,DLGAP1,CHRNA4,EPS15L1,CLCN3,CLTB,CLTC,ABCG2,CNGA3,HOMER3,CNR1,PICK1,CNTFR,CNTN1,AKAP7,AKAP6,WHRN,CABP1,AKAP5,MYRIP,NECTIN3,CLIP3,SNCAIP,SIPA1L1,RIMS4,CNTNAP2,ERC2,ARHGEF4,RIMS2,MYADM,ARHGAP32,RIPOR2,SNPH,TBC1D5,KCTD8,DAPK3,AIF1L,DBN1,HEPH,SNAP91,GRIN3A,DMD,SLC29A4,SHANK1,SLC12A6,DRP2,DNM1L,WDPCP,EDNRA,EDNRB,EGFR,PLEKHA1,TNK2,ENO2,MFSD10,RASGRP2,EPHB1,GPHN,STX2,ERBB2,ERBB4,APC2,ADGRV1,SH3YL1,PTK2B,DLC1,FCGR1A,OLFM1,AMOTL2,NBEA,PDLIM5,NSG1,AP4B1,FYN,MEGF11,MEGF10,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,RAPGEF6,DISC1,INPP5K,IGSF5,FERMT2,MCHR1,GPER1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,BVES,AP4S1,PACSIN2,SYNPO,CFAP126,IL6R,TMEM240,LRRTM1,JAK2,KCNB1,KCND2,KCNJ16,KCNQ3,L1CAM,LAMP2,SYTL4,MYO6,MYO7A,SLC11A2,NTRK2,OCRL,OXTR,P2RY1,PALM,PCDH8,PDE4A,PDE4D,ABCB1,PKD1,PLCD1,PLEC,FXYD1,LRP12,DRAM2,PRKAB2,PRKCB,MAPK3,PRPH,CNNM2,NDUFS7,PTCH1,PTH1R,PTK2,PTPRO,TMEM231,IQSEC3,RASGRF1,RDX,RET,ROBO1,KIRREL1,ROBO2,LRRK2,ATAT1,FERMT1,SHC4,CNKSR2,NLGN1,SLC2A5,SLC8A1,SLC12A2,SLC14A1,SLC22A4,SNAP25,FAIM2,FNBP1,ERC1,UNC5B,DDN,CLASP2,CLSTN2,ZC4H2,ERBIN,KANK1,SEPT3,SYNE2,ARC,SYP,SYT1,MTCL1,SYNE1,TEK,AP4E1,GPR161,TIAM1,TLR4,TPM1,RGMB,RUSC1,TSC2,VLDLR,P2RY12,LAT2,CLDND1,XPO1,NDRG4,CRB2,ANKS1B,LAMP5,FZD3,IFT88,NETO1,SPATA13" GO: Cellular Component GO:0070382 exocytic vesicle 7.89E-12 7.92E-09 4.17E-10 3.12E-09 57 172 "SYN3,DOC2A,AMPH,BIN1,APBA2,MADD,ATP6V1G2,MTMR2,HAP1,SYNGR3,DGKI,CBARP,CLCN3,AKAP7,SNCAIP,DBI,SNAP91,SV2B,DNM1,DNM1L,COPS4,STX2,VTI1B,SYT3,BRSK1,GABBR1,SYT17,DISC1,GRIA2,ICA1,MYLK2,IGF1,SLC6A17,STXBP5,SYTL4,SCAMP5,MYO5A,PDE4B,PTPRN,PTPRN2,LRRK2,STX1B,LGI3,SNAP25,SNCA,STX1A,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,TRIM9,SLC30A3,MFF,SLC17A7" GO: Cellular Component GO:0008021 synaptic vesicle 5.04E-11 5.07E-08 2.53E-09 1.90E-08 52 156 "SYN3,DOC2A,AMPH,BIN1,APBA2,MADD,ATP6V1G2,MTMR2,HAP1,SYNGR3,DGKI,CBARP,CLCN3,SNCAIP,DBI,SNAP91,SV2B,DNM1,DNM1L,COPS4,STX2,VTI1B,BRSK1,GABBR1,DISC1,GRIA2,ICA1,MYLK2,SLC6A17,STXBP5,SCAMP5,MYO5A,PDE4B,PTPRN,PTPRN2,LRRK2,STX1B,LGI3,SNAP25,SNCA,STX1A,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,TRIM9,SLC30A3,MFF,SLC17A7" GO: Cellular Component GO:0098590 plasma membrane region 7.91E-11 7.95E-08 3.78E-09 2.84E-08 208 1041 "ACHE,ADCY6,FZD9,ADORA1,ADORA2A,UNC5A,LRFN2,ADRB2,AP2A1,KCTD16,LRFN1,ANK2,FGD2,APC,EPB41L5,SHROOM2,AQP6,CASK,ARRB1,ARRB2,NUMB,ATP1A1,SLC4A4,ATP1B3,ATP2B2,BBS2,MPDZ,RGS9,HCN2,PROM1,DST,SYNJ1,SYNJ2,MTMR2,SGCE,CA4,DDR1,CAMK2A,CBLN1,SCARB1,ENTPD2,DGKI,ARHGEF2,SEPT7,CDH2,DLGAP2,DLGAP1,CHRNA4,CLCN3,CLTB,ABCG2,CNGA3,HOMER3,PICK1,CNTFR,AKAP7,AKAP6,WHRN,CABP1,AKAP5,MYRIP,NECTIN3,SNCAIP,SIPA1L1,RIMS4,CNTNAP2,ERC2,ARHGEF4,RIMS2,ARHGAP32,RIPOR2,SNPH,KCTD8,AIF1L,DBN1,HEPH,SNAP91,GRIN3A,DMD,SLC29A4,SHANK1,SLC12A6,DRP2,WDPCP,EGFR,PLEKHA1,ENO2,MFSD10,RASGRP2,GPHN,STX2,ERBB2,ERBB4,APC2,ADGRV1,SH3YL1,DLC1,OLFM1,AMOTL2,NBEA,PDLIM5,NSG1,MEGF11,MEGF10,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,RAPGEF6,DISC1,INPP5K,IGSF5,FERMT2,MCHR1,GPER1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,BVES,PACSIN2,SYNPO,CFAP126,IL6R,TMEM240,LRRTM1,JAK2,KCNB1,KCND2,KCNJ16,L1CAM,SYTL4,MYO6,MYO7A,SLC11A2,NTRK2,OXTR,P2RY1,PALM,PCDH8,PDE4A,PDE4D,ABCB1,PKD1,PLEC,FXYD1,DRAM2,PRKAB2,PRKCB,MAPK3,PRPH,CNNM2,NDUFS7,PTCH1,PTH1R,PTK2,PTPRO,TMEM231,IQSEC3,RASGRF1,RDX,ROBO1,KIRREL1,ROBO2,LRRK2,FERMT1,SHC4,CNKSR2,NLGN1,SLC2A5,SLC8A1,SLC12A2,SLC14A1,SLC22A4,SNAP25,FAIM2,ERC1,DDN,CLASP2,CLSTN2,ZC4H2,ERBIN,KANK1,SEPT3,SYNE2,ARC,SYP,SYT1,MTCL1,SYNE1,TEK,GPR161,TIAM1,TPM1,RUSC1,TSC2,P2RY12,CLDND1,NDRG4,ANKS1B,LAMP5,FZD3,NETO1,SPATA13" GO: Cellular Component GO:0030427 site of polarized growth 1.05E-10 1.05E-07 4.79E-09 3.59E-08 58 187 "NDRG2,APBB2,APC,ARHGEF7,CALM1,HAP1,PTBP2,CBARP,NGEF,CNR1,WHRN,AATK,CSNK1E,ERC2,BOC,DBN1,TIAM2,PARD6A,DPYSL2,FRY,TNK2,PTK2B,OLFM1,FGF13,DCTN2,PCLO,STMN2,GRIA2,LRRTM1,L1CAM,ZFYVE27,MAPT,MYO5A,NTRK2,PCDH9,TMOD2,PTCH1,PTPRO,RASGRF1,CRTAC1,LRRK2,SIRT2,SNAP25,SNCA,CLASP2,COBL,EXOC7,PCDHGB1,FRYL,DICER1,SIRT1,TIAM1,PARD3,TSC1,TSC2,LAMP5,MAP3K12,GDPD5" GO: Cellular Component GO:0030426 growth cone 3.07E-10 3.09E-07 1.34E-08 1.01E-07 56 182 "NDRG2,APBB2,APC,ARHGEF7,CALM1,HAP1,PTBP2,CBARP,NGEF,CNR1,WHRN,AATK,CSNK1E,ERC2,BOC,DBN1,TIAM2,PARD6A,DPYSL2,TNK2,PTK2B,OLFM1,FGF13,DCTN2,PCLO,STMN2,GRIA2,LRRTM1,L1CAM,ZFYVE27,MAPT,MYO5A,NTRK2,PCDH9,TMOD2,PTCH1,PTPRO,RASGRF1,CRTAC1,LRRK2,SIRT2,SNAP25,SNCA,CLASP2,COBL,EXOC7,PCDHGB1,DICER1,SIRT1,TIAM1,PARD3,TSC1,TSC2,LAMP5,MAP3K12,GDPD5" GO: Cellular Component GO:0045211 postsynaptic membrane 1.79E-09 1.80E-06 7.34E-08 5.50E-07 63 225 "ACHE,ADORA1,ADORA2A,LRFN2,KCTD16,LRFN1,ANK2,ARRB1,ARRB2,MPDZ,CBLN1,DLGAP2,DLGAP1,CHRNA4,HOMER3,PICK1,CABP1,NECTIN3,SIPA1L1,ARHGAP32,KCTD8,DBN1,SNAP91,GRIN3A,DMD,SHANK1,DRP2,GPHN,ERBB2,NBEA,PDLIM5,NSG1,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,DISC1,GPER1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,SYNPO,LRRTM1,KCNB1,KCND2,NTRK2,P2RY1,PCDH8,IQSEC3,SHC4,CNKSR2,NLGN1,FAIM2,CLSTN2,ZC4H2,ARC,SYNE1,RUSC1,ANKS1B,NETO1" GO: Cellular Component GO:0033267 axon part 1.83E-09 1.83E-06 7.34E-08 5.50E-07 79 309 "ADORA1,ADORA2A,AMPH,BIN1,KCNAB2,APC,SPTBN4,ATP6V0A1,KIF1A,SYNJ1,SYNJ2,CACNA1B,CALB1,CALB2,HAP1,CCK,DGKI,SEPT7,CLCN3,CLTC,CRHBP,AATK,CNTNAP2,ERC2,BOC,DBN1,SNAP91,PARD6A,SV2B,DNM1,DPYSL2,OLFM1,GABBR1,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPER1,PCLO,GRIA2,GRIK4,GRIK5,MYLK2,KCNQ3,L1CAM,MAPT,MBP,BLOC1S2,NPY,NRCAM,NTRK2,OPA1,POLG,PTCH1,PTPRN,PTPRN2,ROBO1,ROBO2,LRRK2,KCNIP3,SCN8A,SIRT2,SNAP25,SNCA,SPTAN1,NFASC,CLASP2,STXBP1,SYN1,SYN2,SYP,SYT1,COBL,TIAM1,PARD3,UCHL1,KCNAB1,AP3B2" GO: Cellular Component GO:0031252 cell leading edge 2.92E-09 2.93E-06 1.13E-07 8.45E-07 93 389 "ACTN1,ADORA1,ADORA2A,UNC5A,AMPH,CDC42BPA,FGD2,APBB2,APC,EPB41L5,GAS7,HCN2,DST,SYNJ2,ARHGEF7,SGCE,WASF1,LDB2,ARHGEF2,CDH2,ARHGEF6,AKAP5,CDC42BPB,SH2B1,CNTNAP2,ARHGEF4,MYADM,AIF1L,DBN1,DCTN1,TIAM2,PARD6A,PLEKHA1,RASGRP2,MTSS1L,STX2,APC2,SH3YL1,PTK2B,DLC1,FER,BAIAP2,EVL,GABBR1,GABRG2,IQGAP2,INPP5K,FERMT2,GPER1,STMN2,CIT,GSN,PACSIN2,KCNB1,MKLN1,DBNL,LAYN,MYO5A,MYO6,PALM,PDE4A,PSD,BCAS3,GDPD2,PTK2,PTPN13,PTPRO,RDX,ROBO1,ROBO2,CLIP1,S100B,FERMT1,ASAP3,ABLIM3,CCDC88A,SNAP25,DDN,CLASP2,SAMSN1,KANK1,SYNE2,COBL,MCF2L,TIAM1,MTMR14,TPM1,TSC1,PLEKHH2,WIPF1,LAMP5,DOCK8,SPATA13" GO: Cellular Component GO:0015630 microtubule cytoskeleton 5.96E-09 5.99E-06 2.22E-07 1.66E-06 213 1125 "NDRG2,AXIN2,MTUS1,WDR35,CEP126,CCDC146,PKP4,KCNAB2,APC,SHROOM2,RGS20,DNAH17,MARK4,DYNLL1,KIF1A,TTLL9,BBS2,DST,SYNJ1,SYNJ2,CALM1,HAP1,CAMK2B,SPAG9,PRC1,KRIT1,USP2,ARHGEF2,SEPT7,CDC25B,LRWD1,DIS3L,RAB28,CLTC,CCDC151,WHRN,RTTN,RBM39,CRHBP,CRMP1,NCOR1,ARHGEF10,PDE4DIP,KATNAL2,SNPH,KIF26A,KIAA0586,IST1,DNAL1,DCTN1,KIAA0753,ALKBH8,KIF19,DNM1,DNAH9,MED12,DYNC1I1,DPYSL2,PDCD6IP,DNM1L,FRY,DCTN4,TUBD1,ERCC2,CEP85L,APC2,KATNAL1,REEP2,TUBA1B,TUBB3,CEP78,ZMYND10,FER,FGF13,MAD2L2,RGPD5,DCTN2,STAU2,TPPP3,BRSK1,NEURL4,ZNF274,IQGAP2,DISC1,SEPT9,TUBGCP4,TUBA8,SPIN1,CBX1,MAP7D2,DCLK2,CNTRL,TPPP,DIDO1,SPACA9,AGBL5,CFAP126,LRRCC1,KIF2A,KIF5A,KIFC3,CAMK2N2,STMN1,SYTL4,MAP2,MAP4,MAP6,MAPT,MARK1,MBNL1,MID1,POC1B,BLOC1S2,MYO5A,CCDC13,NEK1,NFE2L2,DNHD1,CHAMP1,PDE4B,PDE4D,OLA1,CCSER2,SNX10,GPSM2,JAKMIP1,FSD1,PRKACB,CEP41,PRKCB,MAPK3,KLK6,BCAS3,CNTLN,PTK2,SPDL1,EML5,PPP2R3C,CEP97,RAD51D,RBBP6,DPF2,FIGN,KIF7,RIC8B,TCP11L1,RPS6KA2,MAP6D1,ATAT1,CLIP1,STX1B,ATXN7,KIF27,KIF21A,KIF16B,SHMT2,CCDC92,SYBU,DZIP1,PPP4R3A,WDR47,PKNOX2,SLC8A1,RADIL,SIRT2,CDK5RAP3,CDK5RAP2,IFT122,KIF13A,ZNF415,USP33,SPATA7,SP4,MYCBP2,SPTAN1,TSPYL2,CLASP2,SS18,STAU1,CEP68,TTBK2,MMS19,TACC1,MTCL1,EXOC7,FBXW11,TBL1X,RPGRIP1L,CLASP1,SYNE1,OBSL1,DNAH7,TIAM1,ERCC6L2,PARD3,NEIL2,RUSC1,TUBB2A,TUBB1,CCDC14,CLIP2,WRN,KLC2,XRCC4,POLR3H,EML6,DNALI1,EVI5,TUBA1A,DNAH10,AAAS,IFT88,LAS1L" GO: Cellular Component GO:0030133 transport vesicle 1.55E-07 1.55E-04 5.55E-06 4.16E-05 85 374 "SYN3,AP2A1,SYT13,DOC2A,AMPH,BIN1,APBA2,AQP6,MADD,ATP6V1G2,MTMR2,IL33,CA4,HAP1,SYNGR3,DGKI,COPB2,CBARP,CLCN3,CLTB,CLTC,RAB26,AKAP7,MYRIP,SEC31B,SNCAIP,SEC24C,DBI,SNAP91,SV2B,DNM1,DNM1L,COPS4,RABEPK,STX2,NCALD,F5,F8,SEC24B,FGFR3,SEC23B,VTI1B,SYT3,ATP2C1,BRSK1,GABBR1,GALNT15,SYT17,DISC1,PCLO,GRIA2,ICA1,MYLK2,IGF1,SLC6A17,STXBP5,SYTL4,SCAMP5,MYO5A,NPTX1,PCSK1,PDE4B,PTPRN,PTPRN2,LRRK2,STX1B,AP1AR,COPZ1,SEC31A,LGI3,SNAP25,SNCA,STX1A,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,VGF,TRIM9,SLC30A3,MFF,SLC17A7" GO: Cellular Component GO:0048786 presynaptic active zone 1.69E-07 1.70E-04 5.87E-06 4.40E-05 18 37 "ADORA1,ADORA2A,PPFIA4,PPFIA3,DGKI,CDH2,RIMS4,ERC2,RIMS2,GAD1,GPER1,PCLO,NTRK2,ERC1,SYN1,SYP,SLC17A7,FZD3" GO: Cellular Component GO:0042734 presynaptic membrane 5.05E-07 5.07E-04 1.69E-05 1.27E-04 27 76 "ACHE,ADORA1,ADORA2A,KCTD16,CASK,CAMK2A,PICK1,SNCAIP,ERC2,RIMS2,SNPH,KCTD8,SNAP91,GABBR1,GPER1,GRIA2,GRIK4,GRIK5,GRM2,GRM8,L1CAM,PCDH8,SNAP25,ERC1,SEPT3,SYP,SYT1" GO: Cellular Component GO:0005874 microtubule 5.60E-07 5.63E-04 1.82E-05 1.36E-04 92 426 "AXIN2,MTUS1,KCNAB2,APC,SHROOM2,RGS20,DNAH17,DYNLL1,KIF1A,TTLL9,DST,SYNJ1,SYNJ2,CALM1,PRC1,KRIT1,ARHGEF2,CRHBP,NCOR1,KATNAL2,SNPH,KIF26A,DCTN1,KIF19,DNM1,DNAH9,DYNC1I1,DPYSL2,DNM1L,TUBD1,APC2,KATNAL1,REEP2,TUBA1B,TUBB3,FGF13,DCTN2,STAU2,TPPP3,IQGAP2,DISC1,SEPT9,TUBGCP4,TUBA8,DCLK2,TPPP,SPACA9,KIF2A,KIF5A,KIFC3,STMN1,MAP2,MAP4,MAP6,MAPT,MID1,MYO5A,JAKMIP1,FSD1,BCAS3,EML5,FIGN,TCP11L1,MAP6D1,ATAT1,CLIP1,KIF27,KIF21A,KIF16B,SYBU,WDR47,SLC8A1,RADIL,SIRT2,CDK5RAP3,CDK5RAP2,KIF13A,CLASP2,SS18,TBL1X,CLASP1,DNAH7,TIAM1,NEIL2,RUSC1,TUBB2A,TUBB1,CLIP2,KLC2,EML6,TUBA1A,DNAH10" GO: Cellular Component GO:0005938 cell cortex 1.41E-06 1.42E-03 4.42E-05 3.31E-04 63 266 "ACTN1,AXIN2,OSBPL8,PDZD4,APC,SHROOM2,SPTBN4,RGS20,PLA2G4C,DST,ARHGEF7,USP2,SEPT7,CDH2,CABP1,MYRIP,AKAP12,MYADM,ARHGAP32,DBN1,PARD6A,WDPCP,FRY,EPB41,EPB41L2,MTSS1L,PTK2B,DLC1,FER,FGF1,GAD1,SEPT9,GCK,FERMT2,PCLO,GSN,SCIN,MKLN1,DBNL,MYO6,MYO7A,GPSM2,PTK2,RDX,RIC8B,SNCA,FNBP1,ZHX3,SPTAN1,SPTB,CLASP2,PHLDB1,ARHGEF9,COBL,EXOC7,PDLIM2,CLASP1,FRYL,PARD3,TSC1,PLEKHH2,WIPF1,SPIRE1" GO: Cellular Component GO:0099568 cytoplasmic region 1.81E-06 1.82E-03 5.50E-05 4.12E-04 73 325 "ACTN1,AXIN2,OSBPL8,PDZD4,APC,SHROOM2,SPTBN4,RGS20,PLA2G4C,KIF1A,DST,ARHGEF7,HAP1,CAMK2A,USP2,SEPT7,CDH2,CABP1,MYRIP,AKAP12,MYADM,ARHGAP32,DBN1,PARD6A,WDPCP,FRY,EPB41,EPB41L2,MTSS1L,PTK2B,DLC1,FER,FGF1,GAD1,SEPT9,GCK,FERMT2,PCLO,GRIA2,GSN,SCIN,MKLN1,DBNL,BLOC1S2,MYO6,MYO7A,OPA1,GPSM2,PTK2,RDX,RIC8B,LRRK2,SNCA,FNBP1,ZHX3,SPTAN1,SPTB,CLASP2,PHLDB1,ARHGEF9,COBL,EXOC7,PDLIM2,CLASP1,FRYL,PARD3,TSC1,UCHL1,PLEKHH2,WIPF1,SPIRE1,KCNAB1,AP3B2" GO: Cellular Component GO:0031256 leading edge membrane 2.29E-06 2.30E-03 6.76E-05 5.06E-04 41 150 "ADORA1,ADORA2A,UNC5A,AMPH,FGD2,APC,EPB41L5,HCN2,SYNJ2,SGCE,ARHGEF2,AKAP5,CNTNAP2,ARHGEF4,AIF1L,PLEKHA1,RASGRP2,APC2,SH3YL1,DLC1,GABBR1,GABRG2,INPP5K,FERMT2,GPER1,PACSIN2,KCNB1,MYO6,PALM,PDE4A,ROBO1,ROBO2,FERMT1,DDN,CLASP2,KANK1,SYNE2,TIAM1,TPM1,LAMP5,SPATA13" GO: Cellular Component GO:0044306 neuron projection terminus 2.84E-06 2.85E-03 7.92E-05 5.93E-04 50 199 "ADORA1,AMPH,BIN1,KCNAB2,APC,ATP6V0A1,SYNJ1,SYNJ2,CACNA1B,CALB1,CALB2,HAP1,CCK,DGKI,SEPT7,CLCN3,CLTC,CRHBP,ERC2,SNAP91,SV2B,DMD,DPYSL2,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPER1,PCLO,GRIA2,GRIK4,GRIK5,MYLK2,L1CAM,NPY,NTRK2,POLG,PTPRN,PTPRN2,LRRK2,KCNIP3,SNAP25,SNCA,STXBP1,SYN1,SYN2,SYP,SYT1,UCHL1" GO: Cellular Component GO:0044430 cytoskeletal part 2.84E-06 2.85E-03 7.92E-05 5.93E-04 258 1520 "ACTN1,NDRG2,ADD1,ADD2,AXIN2,ADORA2A,MTUS1,WDR35,CEP126,CDC42BPA,CCDC146,MYH7B,PKP4,KCNAB2,APC,GAS7,SHROOM2,SPTBN4,RGS20,DNAH17,MARK4,DYNLL1,MYOM1,KIF1A,TTLL9,BBS2,DST,SYNJ1,SYNJ2,LURAP1,CALM1,HAP1,CAMK2B,SPAG9,PRC1,KRIT1,USP2,ARHGEF2,SEPT7,CDC25B,CDH2,DLGAP2,LRWD1,DIS3L,RAB28,MYL6B,CLTC,CCDC151,WHRN,RTTN,CDC42BPB,RBM39,CRHBP,CRMP1,NCOR1,ARHGEF10,PDE4DIP,MYADM,KATNAL2,SNPH,HDAC4,KIF26A,KIAA0586,IST1,DAPK3,AIF1L,DNAL1,DBN1,DCTN1,KIAA0753,KIF19,DNM1,DNAH9,MED12,DYNC1I1,DPYSL2,PDCD6IP,DNM1L,FRY,DCTN4,TUBD1,EPB41,EPB41L2,MTSS1L,ERCC2,CEP85L,APC2,KATNAL1,REEP2,TUBA1B,TUBB3,DLC1,CEP78,ZMYND10,FGF13,MAD2L2,RGPD5,DCTN2,STAU2,TPPP3,BRSK1,FYN,NEURL4,ZNF274,IQGAP2,DISC1,SEPT9,GCK,TUBGCP4,TUBA8,SPIN1,CBX1,DCLK2,FERMT2,GPER1,CNTRL,TPPP,DIDO1,SPACA9,GSN,SYNPO,AGBL5,CFAP126,LRRCC1,KIF2A,KIF5A,KIFC3,CAMK2N2,STMN1,SYTL4,MAP2,MAP4,MAP6,MAPT,MBNL1,MID1,POC1B,DBNL,BLOC1S2,MYH3,MYO5A,MYO6,MYO7A,MYO9A,NEFM,NEFH,CCDC13,NEK1,NFE2L2,DNHD1,CHAMP1,PDE4B,PDE4D,TMOD2,OLA1,SNX10,GPSM2,JAKMIP1,FSD1,PRKACB,CEP41,PRKCB,PRPH,BCAS3,GDPD2,CNTLN,PTK2,SPDL1,EML5,PPP2R3C,CEP97,RAD51D,RBBP6,RDX,DPF2,FIGN,KIF7,RIC8B,TCP11L1,RPS6KA2,MAP6D1,ATAT1,CLIP1,STX1B,KIF27,KIF21A,FERMT1,KIF16B,MYO18A,FHOD3,CCDC92,SYBU,DZIP1,ABLIM3,PPP4R3A,WDR47,SLC8A1,RADIL,SIRT2,CDK5RAP3,CDK5RAP2,MYH15,IFT122,KIF13A,MYO16,USP33,SPATA7,SPTAN1,SPTB,TSPYL2,CLASP2,SS18,MPRIP,STAU1,CEP68,TTBK2,STX1A,COBL,MMS19,TACC1,MTCL1,EXOC7,PDLIM2,FBXW11,TBL1X,RPGRIP1L,CLASP1,SYNE1,OBSL1,TEK,DNAH7,TIAM1,ERCC6L2,PARD3,TPM1,TPM2,NEIL2,RUSC1,TSC1,TUBB2A,TUBB1,PLEKHH2,CCDC14,WIPF1,CLIP2,WRN,KLC2,XRCC4,POLR3H,EML6,DNALI1,EVI5,TUBA1A,DNAH10,ACTR3B,AAAS,IFT88,LAS1L" GO: Cellular Component GO:0043195 terminal bouton 3.74E-06 3.76E-03 1.02E-04 7.61E-04 33 112 "ADORA1,AMPH,ATP6V0A1,SYNJ1,CALB1,CALB2,CCK,CLTC,ERC2,SNAP91,SV2B,DPYSL2,GABRB3,CPLX2,CPLX1,PCLO,GRIA2,GRIK4,GRIK5,MYLK2,L1CAM,NPY,NTRK2,POLG,PTPRN2,LRRK2,SNAP25,SNCA,STXBP1,SYN1,SYN2,SYP,SYT1" GO: Cellular Component GO:0001726 ruffle 4.06E-06 4.08E-03 1.04E-04 7.78E-04 44 169 "ACTN1,FGD2,APC,EPB41L5,GAS7,SYNJ2,ARHGEF7,ARHGEF2,SH2B1,ARHGEF4,MYADM,AIF1L,PARD6A,PLEKHA1,RASGRP2,MTSS1L,SH3YL1,DLC1,BAIAP2,INPP5K,CIT,GSN,PACSIN2,MKLN1,DBNL,LAYN,MYO5A,MYO6,PDE4A,PSD,RDX,CLIP1,S100B,FERMT1,ASAP3,CLASP2,SAMSN1,KANK1,COBL,TIAM1,MTMR14,TPM1,WIPF1,SPATA13" GO: Cellular Component GO:0015629 actin cytoskeleton 4.15E-06 4.17E-03 1.04E-04 7.78E-04 97 476 "ACTN1,ADD1,ADD2,AMPH,BIN1,CDC42BPA,MYH7B,GAS7,SHROOM2,CASK,SPTBN4,MYOM1,DST,WASF1,LURAP1,KALRN,HAP1,SEPT7,ZBED1,CDH2,CFL2,MYL6B,CNN3,WHRN,MYRIP,CDC42BPB,MYADM,ARHGAP32,HDAC4,DAPK1,DAPK3,AIF1L,DBN1,DCTN1,PARD6A,DMD,DCTN4,EPB41,EPB41L2,MTSS1L,APC2,CORO2B,DLC1,FER,BAIAP2,FLNC,DCTN2,PDLIM5,ABLIM2,FYB1,FYN,DENND2A,IQGAP2,SEPT9,GCK,TCERG1,FERMT2,CIT,GSN,SYNPO,DBNL,MYH3,MYO5A,MYO6,MYO7A,MYO9A,TMOD2,POU6F1,GDPD2,PTK2,RDX,FERMT1,MYO18A,FHOD3,ABLIM3,PKNOX2,MYH15,TTC17,SNAP25,SNCA,MYO16,SPTAN1,SPTB,MPRIP,STX1A,ARC,COBL,PDLIM2,TEK,TPM1,TPM2,SYNPO2,TSC1,PLEKHH2,WIPF1,ZNF74,ACTR3B" GO: Cellular Component GO:0099501 exocytic vesicle membrane 4.24E-06 4.26E-03 1.04E-04 7.78E-04 22 61 "SYN3,DOC2A,AMPH,SYNGR3,CBARP,SV2B,DNM1L,GRIA2,ICA1,SLC6A17,SCAMP5,PTPRN2,LRRK2,STX1A,SYN1,SYN2,SYP,SYT1,SYT5,DMXL2,SLC30A3,SLC17A7" GO: Cellular Component GO:0030672 synaptic vesicle membrane 4.24E-06 4.26E-03 1.04E-04 7.78E-04 22 61 "SYN3,DOC2A,AMPH,SYNGR3,CBARP,SV2B,DNM1L,GRIA2,ICA1,SLC6A17,SCAMP5,PTPRN2,LRRK2,STX1A,SYN1,SYN2,SYP,SYT1,SYT5,DMXL2,SLC30A3,SLC17A7" GO: Cellular Component GO:0044295 axonal growth cone 4.55E-06 4.57E-03 1.09E-04 8.15E-04 14 29 "APC,AATK,BOC,DBN1,PARD6A,OLFM1,L1CAM,MAPT,PTCH1,SNAP25,CLASP2,COBL,TIAM1,PARD3" GO: Cellular Component GO:0043679 axon terminus 4.71E-06 4.73E-03 1.10E-04 8.25E-04 47 186 "ADORA1,AMPH,BIN1,KCNAB2,ATP6V0A1,SYNJ1,SYNJ2,CACNA1B,CALB1,CALB2,HAP1,CCK,DGKI,SEPT7,CLCN3,CLTC,CRHBP,ERC2,SNAP91,SV2B,DPYSL2,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPER1,PCLO,GRIA2,GRIK4,GRIK5,MYLK2,L1CAM,NPY,NTRK2,POLG,PTPRN,PTPRN2,LRRK2,KCNIP3,SNAP25,SNCA,STXBP1,SYN1,SYN2,SYP,SYT1" GO: Cellular Component GO:0005905 clathrin-coated pit 1.18E-05 1.19E-02 2.69E-04 2.02E-03 23 69 "AP2A1,AP2A2,ARRB1,ARRB2,SYNJ1,HIP1R,EPS15L1,CLTB,CLTC,TBC1D5,SNAP91,DNM1L,EGFR,TNK2,AP4B1,AP4S1,MYO6,OCRL,LRP12,ATAT1,FNBP1,AP4E1,VLDLR" GO: Cellular Component GO:0012506 vesicle membrane 1.63E-05 1.63E-02 3.63E-04 2.72E-03 104 535 "SYN3,ACTN1,AP2A1,AP2A2,DOC2A,AMPH,AQP6,ARRB1,CADPS,MARCH3,ATP2A2,ATP6V0A1,SYNJ1,AP1M1,CA4,CAMK2A,CAMK2B,CAMK2G,HIP1R,SCARB1,SYNGR3,COPB2,CBARP,TAOK2,CLCN3,CLTB,CLTC,RAB26,PICK1,MYRIP,SEC31B,SEC24C,APPL1,CYBB,TBC1D5,SNAP91,SV2B,DNM1L,EGFR,TNK2,MFSD10,RAB9B,NCALD,CLVS1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SYT3,CSPG5,GAD1,GPER1,GRIA2,PACSIN2,ICA1,INPP5B,SLC6A17,KIFC3,STXBP5,LAMP2,SYTL4,SCAMP5,DBNL,MSR1,MYO6,OCRL,ZDHHC8,PKD1,SH3KBP1,PTCH1,PTPRN,PTPRN2,MARCH1,SNX22,LRRK2,CLIP1,COPZ1,FNDC3A,SEC31A,EPN2,SLC11A1,SNCA,ATP10B,STX1A,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,GPR161,UBC,VGF,WNT7A,ATP6V0E2,SPIRE1,LAMP5,SLC30A3,SLC17A7,MARCH8,IFT88,AP3B2" GO: Cellular Component GO:0030659 cytoplasmic vesicle membrane 2.09E-05 2.10E-02 4.57E-04 3.42E-03 100 513 "SYN3,ACTN1,AP2A1,AP2A2,DOC2A,AMPH,AQP6,ARRB1,CADPS,MARCH3,ATP6V0A1,AP1M1,CA4,CAMK2A,CAMK2B,CAMK2G,HIP1R,SCARB1,SYNGR3,COPB2,CBARP,TAOK2,CLCN3,CLTB,CLTC,RAB26,PICK1,MYRIP,SEC31B,SEC24C,CYBB,TBC1D5,SNAP91,SV2B,DNM1L,EGFR,TNK2,MFSD10,RAB9B,NCALD,CLVS1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SYT3,CSPG5,GAD1,GPER1,GRIA2,PACSIN2,ICA1,INPP5B,SLC6A17,KIFC3,STXBP5,LAMP2,SYTL4,SCAMP5,DBNL,MSR1,MYO6,OCRL,ZDHHC8,PKD1,SH3KBP1,PTCH1,PTPRN,PTPRN2,MARCH1,SNX22,LRRK2,CLIP1,COPZ1,SEC31A,EPN2,SLC11A1,SNCA,ATP10B,STX1A,SYN1,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,GPR161,UBC,VGF,WNT7A,ATP6V0E2,SPIRE1,LAMP5,SLC30A3,SLC17A7,MARCH8,IFT88,AP3B2" GO: Cellular Component GO:0043197 dendritic spine 4.06E-05 4.08E-02 8.67E-04 6.50E-03 38 151 "ASIC1,ACTN1,ADD1,ADORA1,ADRB2,ARRB1,ARRB2,ATP1A3,MTMR2,P2RX6,DGKI,CNN3,AKAP5,SIPA1L1,ARHGAP32,DBN1,SHANK1,BAIAP2,GABBR1,GPER1,GRIA2,SYNPO,MYLK2,ITPKA,KCND2,KCNN2,LAMA2,NTRK2,PALM,PDE4B,PTPRO,NLGN1,SLC8A1,ARC,SYNE1,TIAM1,ANKS1B,FXR1" GO: Cellular Component GO:0044304 main axon 4.21E-05 4.23E-02 8.81E-04 6.60E-03 23 74 "ADORA1,ADORA2A,BIN1,KCNAB2,SPTBN4,CCK,CRHBP,CNTNAP2,DNM1,GABBR1,KCNQ3,MAPT,MBP,NRCAM,ROBO1,ROBO2,SCN8A,SIRT2,SPTAN1,NFASC,TIAM1,PARD3,KCNAB1" GO: Cellular Component GO:0031253 cell projection membrane 5.12E-05 5.15E-02 1.03E-03 7.74E-03 69 332 "ADCY6,FZD9,ADORA1,ADORA2A,UNC5A,FGD2,APC,EPB41L5,CASK,BBS2,RGS9,HCN2,PROM1,SYNJ2,SGCE,CA4,SCARB1,ENTPD2,ARHGEF2,CLTB,CNGA3,WHRN,AKAP5,CNTNAP2,ARHGEF4,RIPOR2,AIF1L,DMD,PLEKHA1,MFSD10,RASGRP2,APC2,ADGRV1,SH3YL1,DLC1,GABBR1,GABRG2,INPP5K,FERMT2,MCHR1,GPER1,BVES,PACSIN2,KCNB1,MYO6,SLC11A2,PALM,PDE4A,ABCB1,PKD1,PRKCB,PRPH,PTCH1,PTH1R,TMEM231,ROBO1,KIRREL1,ROBO2,FERMT1,DDN,CLASP2,KANK1,SYNE2,GPR161,TIAM1,TPM1,NDRG4,LAMP5,SPATA13" GO: Cellular Component GO:0030658 transport vesicle membrane 5.14E-05 5.17E-02 1.03E-03 7.74E-03 39 158 "SYN3,AP2A1,DOC2A,AMPH,AQP6,CA4,SYNGR3,CBARP,CLCN3,CLTB,CLTC,RAB26,SEC31B,SEC24C,SV2B,DNM1L,NCALD,SEC24B,SEC23B,VTI1B,SYT3,GRIA2,ICA1,SLC6A17,SYTL4,SCAMP5,PTPRN,PTPRN2,LRRK2,SEC31A,STX1A,SYN1,SYN2,SYP,SYT1,SYT5,DMXL2,SLC30A3,SLC17A7" GO: Cellular Component GO:0044309 neuron spine 5.52E-05 5.55E-02 1.09E-03 8.15E-03 38 153 "ASIC1,ACTN1,ADD1,ADORA1,ADRB2,ARRB1,ARRB2,ATP1A3,MTMR2,P2RX6,DGKI,CNN3,AKAP5,SIPA1L1,ARHGAP32,DBN1,SHANK1,BAIAP2,GABBR1,GPER1,GRIA2,SYNPO,MYLK2,ITPKA,KCND2,KCNN2,LAMA2,NTRK2,PALM,PDE4B,PTPRO,NLGN1,SLC8A1,ARC,SYNE1,TIAM1,ANKS1B,FXR1" GO: Cellular Component GO:0005802 trans-Golgi network 6.50E-05 6.54E-02 1.26E-03 9.42E-03 49 216 "SYS1,KIAA1324,MARCH4,AMPH,LGR5,RGS20,CHID1,STX16,AP1M1,RAB29,CA4,CABP7,AP4M1,LRBA,CLTB,CLTC,CLIP3,USP6NL,OPTN,RABEPK,CLVS1,NBEA,ATP2C1,AP4B1,SYT17,INPP5K,ARFIP1,RAB30,GPER1,PCLO,AP4S1,PACSIN2,TJAP1,SCAMP5,SLC11A2,OCRL,MARCH1,LRRK2,ATXN2,MYO18A,SNAP25,KIF13A,FNBP1,NMNAT2,CLASP2,AP4E1,PLD4,IFT88,AP3B2" GO: Cellular Component GO:0098791 Golgi subcompartment 9.29E-05 9.34E-02 1.76E-03 1.32E-02 67 326 "SYS1,HACE1,KIAA1324,MARCH4,AMPH,LGR5,RGS20,ARSE,CHID1,STX16,AP1M1,RAB29,CA4,CABP7,AP4M1,LRBA,B4GALT6,CLTB,CLTC,CLIP3,USP6NL,OPTN,APH1A,GOLGA7,RABEPK,CLVS1,NBEA,ATP2C1,FUT9,AP4B1,SYT17,INPP5K,ARFIP1,GGTA1P,RAB30,FUT10,GPER1,PCLO,CIT,AP4S1,PACSIN2,ICA1,TJAP1,SCAMP5,SLC11A2,NUCB2,OCRL,MARCH1,GAL3ST4,LRRK2,ATXN2,SMPD3,MYO18A,ST6GAL1,SNAP25,KIF13A,FNBP1,NMNAT2,CLASP2,SULF2,NSFL1C,DNMBP,AP4E1,GAL3ST3,PLD4,IFT88,AP3B2" GO: Cellular Component GO:0031410 cytoplasmic vesicle 1.03E-04 1.04E-01 1.92E-03 1.44E-02 223 1355 "SYN3,ACTN1,ADD2,AXIN2,TEX22,AP2A1,AP2A2,ADGRF5,SYT13,DOC2A,AMPH,BIN1,OGT,APBA2,AQP6,MADD,ARHGDIG,ARRB1,RGS20,ARRB2,CADPS,MARCH3,NUMB,ATP1A1,ATP1B3,ATP6V1G2,ATP6V0A1,ADAM15,MPDZ,DST,BTK,MTMR2,AP1M1,RAB29,IL33,CA4,HAP1,CAMK2A,CAMK2B,CAMK2G,HIP1R,SPAG9,SCARB1,SYNGR3,DGKI,LRBA,ARHGEF2,COPB2,RCBTB2,CBARP,CHGB,TAOK2,CPNE6,CLCN3,TPP1,STOML1,CLTB,CLTC,RAB26,PICK1,AKAP7,MYRIP,SEC31B,ENTPD4,CRHBP,SNCAIP,SEC24C,USP6NL,CYBB,TBC1D5,IST1,DBI,RUSC2,SNAP91,SV2B,DNM1,PDCD6IP,ARRDC4,DNM1L,EDN1,OPTN,EGFR,COPS4,TNK2,TMEM35A,MFSD10,RABEPK,STX2,RAB9B,ERBB2,NCALD,TLR7,F5,F8,CLVS1,FCGR1A,FCGR1B,SEC24B,FGFR1,FGFR3,BAIAP2,AMOTL2,SEC23B,VTI1B,ANKFY1,SYT3,AKAP3,POMT1,ATP2C1,CSPG5,BRSK1,GABBR1,GALNT15,GAD1,RAPGEF6,SYT17,DISC1,GCK,CRCP,GPER1,PCLO,GRIA2,SPACA9,HBA1,PACSIN2,GABARAPL2,HP,AGFG1,ICA1,MYLK2,IGF1,INPP5B,SLC6A17,KIFC3,KIT,STXBP5,LAMP2,SYTL4,CHIC1,SCAMP5,DBNL,MSR1,MYO5A,MYO6,MYO7A,NCF2,NPTX1,SLC11A2,TBC1D25,OCRL,OPRL1,PALM,PCSK1,PCSK5,PDE4B,PDPK1,ZDHHC8,NLGN3,PIK3C2A,PKD1,ZFYVE21,MAPKAP1,SH3KBP1,PTCH1,PTPRN,PTPRN2,MARCH1,SH3TC2,SNX22,MAP6D1,LRRK2,CLIP1,STX1B,AP1AR,SCN8A,COPZ1,AMBRA1,FNDC3A,SYBU,SEC31A,EPN2,CCDC88A,SLC11A1,LGI3,CXXC4,SNAP25,SNCA,LMBRD1,FNBP1,ATP10B,STX1A,STXBP1,VPS13A,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT5,DMXL2,GPR161,RUSC1,SGK3,UBC,VGF,WIPF1,CLIP2,WNT7A,TRIM9,ATP6V0E2,TMEM198,SPIRE1,LAMP5,SLC30A3,SLC30A4,MFF,HPS4,SLC17A7,PLD4,MARCH8,IFT88,AP3B2" Mouse Phenotype MP:0003633 abnormal nervous system physiology 9.24E-25 6.71E-21 6.71E-21 6.35E-20 459 1997 "ABR,SYN3,ASIC1,ACHE,NDRG2,ADCY8,ADD2,FZD9,ADORA1,ADORA2A,UNC5A,PTCHD1,ADRA1D,ADRA1B,LRFN2,MTA3,SLC24A4,PCDH19,AGT,NME5,SORCS2,SEMA6A,ABCD2,ALK,DOC2A,AMPH,APAF1,APBA2,KCNAB2,GAS7,DDO,SEMA4G,PRX,MADD,CASK,SPTBN4,ARRB1,CADPS,ASPA,CHRD,NUMB,TMEM108,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADGRB3,RGS11,RGS9,HCN2,NRP2,BID,PROM1,KSR1,SYNJ1,ST3GAL5,MTMR2,SGCE,CACNA1G,C5,WASF1,MYRF,BAIAP3,CA8,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAST,CBLN1,CBS,CCK,P2RX6,CD86,SYNGR3,ENTPD2,ARHGEF2,CDH2,DLGAP2,NOG,NUMBL,CACNA2D2,COPB2,ASIC3,CHN1,CHRNA4,NDST3,PLAA,PPT2,CLCN3,TPP1,STOML1,QKI,TMEM184B,ARHGEF6,CNR1,PICK1,WHRN,AKAP5,MAGED1,GAL3ST1,ZNF521,ZNF385A,CLOCK,CREM,CRMP1,CRY2,NCOR2,AATK,CSF1,CSF1R,CSNK1E,CNTNAP2,CST3,SLITRK5,ERC2,RIMS2,GPSM1,CYBB,ARHGAP32,SNPH,HDAC4,KIF26A,MAML1,DGKB,DAPK1,DBN1,KIAA0319,LYPD1,PLPPR4,SNAP91,SV2B,GRIN3A,DNM1,CDON,SHANK1,CPEB2,DMTF1,SLC12A6,DPP6,DRP2,PDCD6IP,DNM1L,E2F5,EDIL3,SEZ6L2,EDN1,EDNRA,CELSR3,APH1A,MBNL2,EGR3,PLXNC1,TMEM35A,EMX2,ENO2,GPHN,ERBB2,ERBB4,APC2,ETV1,ADGRV1,EZH1,NRN1,F5,CLVS1,ZMYND10,FKTN,FDFT1,PRMT5,PPP1R1B,OLFM1,FGF12,FGF13,FGF14,FGFR1,BAIAP2,MAD2L2,SUCO,VTI1B,RGPD5,FOXO3,NBEA,SMC2,PDLIM5,CAMKK2,ATP2C1,CSPG5,FUT9,FYN,MEGF10,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,DISC1,CPLX2,CPLX1,GFRA2,PCDH17,PPARGC1A,GLI2,KDM2B,KCNMB4,DCLK2,GNAO1,MCHR1,GPR37,PCLO,TPPP,GRIA2,GRIK4,GRIK5,GRIN2C,ATE1,GRM2,GRM8,CIT,GSN,GSTM5,LINGO1,FRMD5,HLF,ACOT7,SYNPO,HNMT,HSF2,IRF8,IGF1,IL6ST,INSM1,LRRTM1,ITGA7,ITGAM,ITPKA,KCND2,KCNJ16,KCNK3,KCNN3,KCNQ3,KIF2A,KIF5A,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIG4,SYTL4,MAP6,MAPT,MAT2A,MBD1,MBP,MEF2C,PPM1L,MKLN1,AFDN,GIT1,DBNL,MSI1,BLOC1S2,ADAM22,MYCN,MYO5A,MYO6,MYO7A,NCAM2,NEFH,NELL2,NF1,NFE2L2,NPY,NOVA1,NOVA2,NRCAM,NTRK2,IGSF11,OGG1,OPA1,OPRL1,TREM2,PAX6,PCDH9,PDE4B,ENPP2,PDPK1,SLC10A4,TMOD2,ZDHHC8,ABCB1,NLGN3,NALCN,PLCB2,PLCL1,JAKMIP1,PLEC,PLXNB1,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,PPP1R1A,KANSL1,PRKACB,CEP41,PRKAR1B,MAPK3,MAPK7,MAPK9,MAPK10,SLC26A11,FITM2,HYDIN,RELN,PTCH1,PTN,PTPRE,PTPRO,STRC,SH3TC2,OXR1,RASGRF1,KHDRBS2,RET,PRRT2,RFX3,RIC8B,ROBO1,FBXW7,GLDN,LRRK2,KCNIP3,KCNIP1,STX1B,RYR3,ATXN7,SCN2B,SCN8A,TNFRSF19,KIF27,SH3BP2,SH3GL3,ARX,CPEB3,AMBRA1,NLGN1,ST8SIA1,SLC4A3,SLC6A8,SLC6A11,SIRT2,CCDC88A,NAPB,TET1,SMARCC2,CDK5RAP2,SNAP25,SNCA,FAIM2,SOX11,SP2,SP4,GLT8D1,SPP1,ZNF423,NFASC,SST,SSTR1,SSTR2,ERBIN,SEPT8,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,TACR1,TAL1,ADGRL3,TCF4,DMXL2,CUX2,TRIM2,TCF12,SZT2,SIK3,TEK,SIRT1,AP4E1,ZNF106,THRA,ICAM5,TLR4,NR2E1,RIMBP2,TP53BP2,IL34,NR2C2,TRIO,TRPM2,TSC1,TSC2,UBE3A,UCHL1,UGT8,FLRT2,MGAT5B,VGF,VLDLR,CLIP2,WNT7A,XRCC4,LGI4,ZIC2,ZNF24,KCNT2,TRIM9,ELFN1,NDRG4,SPHK2,CELF4,DPYSL5,ANKS1B,MAP3K12,GDPD5,RNF103,TUBA1A,SLC17A7,KCNAB1,PDSS2,EPM2A,FZD3,DOCK8,RTN4,GJC2,NLRP3,NETO2,NETO1,AP3B2,ST8SIA2,GAN,JPH3" Mouse Phenotype MP:0003635 abnormal synaptic transmission 6.95E-19 5.05E-15 2.53E-15 2.39E-14 210 773 "SYN3,ASIC1,ADCY8,ADD2,ADORA1,ADRA1D,LRFN2,MTA3,SEMA6A,DOC2A,APBA2,MADD,CASK,ARRB1,CADPS,ASPA,CHRD,TMEM108,ATP1A3,ATP2A2,ATP2B2,ADGRB3,RGS9,HCN2,KSR1,SYNJ1,ST3GAL5,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB2,KALRN,CAMK2A,CAMK2B,CBLN1,CCK,DLGAP2,CACNA2D2,CHRNA4,PLAA,CLCN3,ARHGEF6,CNR1,PICK1,AKAP5,ZNF521,CRMP1,SLITRK5,ERC2,RIMS2,CYBB,ARHGAP32,SNPH,DGKB,DAPK1,KIAA0319,LYPD1,PLPPR4,SNAP91,SV2B,GRIN3A,DNM1,SHANK1,CPEB2,SLC12A6,DPP6,SEZ6L2,EDNRA,MBNL2,EGR3,TMEM35A,ENO2,ERBB2,ERBB4,ADGRV1,EZH1,NRN1,CLVS1,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,FOXO3,NBEA,PDLIM5,CAMKK2,CSPG5,FYN,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,DISC1,CPLX2,CPLX1,PCDH17,DCLK2,GNAO1,GPR37,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRM2,GRM8,FRMD5,ACOT7,SYNPO,HNMT,IRF8,IL6ST,LRRTM1,ITPKA,KCND2,KCNK3,KIF5A,KIT,STXBP5,L1CAM,LAMA2,MAP6,MAPT,MAT2A,MBD1,MBP,MEF2C,AFDN,GIT1,MYO5A,NELL2,NOVA2,NRCAM,NTRK2,IGSF11,OPRL1,PAX6,PCDH9,PDE4B,TMOD2,ZDHHC8,NLGN3,NALCN,PPP1R1A,PRKACB,PRKAR1B,MAPK3,MAPK9,SLC26A11,RELN,PTN,PTPRE,RASGRF1,RET,PRRT2,LRRK2,KCNIP3,STX1B,RYR3,ATXN7,SCN8A,SH3GL3,CPEB3,NLGN1,CCDC88A,NAPB,SNAP25,SNCA,SP4,SST,SSTR1,SSTR2,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,TCF4,AP4E1,ICAM5,RIMBP2,TSC1,TSC2,UBE3A,UCHL1,VGF,VLDLR,ZIC2,KCNT2,ELFN1,CELF4,DPYSL5,ANKS1B,RNF103,SLC17A7,KCNAB1,FZD3,NETO2,NETO1,JPH3" Mouse Phenotype MP:0002882 abnormal neuron morphology 5.74E-18 4.17E-14 1.39E-14 1.32E-13 360 1581 "ABR,SYN3,UNC5A,LRFN2,ADRB2,SORCS2,CC2D2A,SPARCL1,SEMA6A,ALCAM,ABCD2,SEMA7A,APAF1,APBB2,GAS7,SEMA4G,PRX,MADD,SPTBN4,CADPS,NCOA1,NUMB,TMEM108,ATP1A3,ATP2B2,KIF1A,ADGRB3,BBS2,RGS9,NRP2,BID,PROM1,BMPR1B,SYNJ2,SGCE,CACNA1G,WASF1,CACNA1A,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,ISPD,CBLN1,CD86,SEPT7,CDH2,DCLK1,ARHGAP33,DLGAP2,NOG,CRLF1,NUMBL,CACNA2D2,CHGB,ASIC3,CHN1,CHN2,CHRNA4,SLIT2,LHX2,PLAA,CLCN3,TPP1,NGEF,VAX2,QKI,TMEM184B,CNGA3,ARHGEF6,CNR1,CNTFR,CNTN1,WHRN,GAL3ST1,ZNF521,CLOCK,CRMP1,CRY2,NCOR1,NCOR2,CLIP3,AATK,CSF1,CSF1R,LRIG1,VCAN,CST3,PLXNA4,SLITRK5,ERC2,RIMS2,ARHGAP32,SNPH,KIF26A,DGKB,BRINP1,DBN1,DCTN1,HEPH,GSDME,SNAP91,GRIN3A,DMD,DNM1,NYAP1,SHANK1,CPEB2,SLC12A6,DPYSL2,DRP2,DTNA,DNM1L,EDIL3,EDN3,EDNRB,HEYL,CELSR3,EGFR,MBNL2,EGR3,PLXNC1,C8orf37,EMX2,ENO2,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,APC2,ETV1,ADGRV1,EYA1,NRN1,TUBB3,FGF13,FGF14,FGFR1,FGFR3,VTI1B,EVL,FLT1,NBEA,SMC2,STAMBP,CAMKK2,AP4B1,BRSK1,FYN,MEGF11,MEGF10,GABBR1,CHL1,GABRB3,GABRG2,GALC,B4GALNT1,IP6K3,SRRM4,GFRA2,PCDH17,PPARGC1A,GLI2,DCLK2,GPT2,GPR37,PCLO,GRIA2,GRIK4,RNF165,GUCY1A1,ACOT7,CPT1C,IGF1,ZIC5,RBPJ,INSM1,LRRTM1,KCND2,KIF2A,KIF5A,KIT,L1CAM,LAMA2,LIFR,SMAD9,MAP2,MAP6,MAPT,MBD1,MBNL1,MBP,SHC3,PPM1L,MITF,MKLN1,AFF1,AFDN,MOV10,GIT1,BLOC1S2,ADAM22,MSR1,MYCN,MYO5A,MYO6,MYO7A,NDP,NEFH,NF1,NFE2L2,NPR2,NRCAM,NTRK2,NTRK3,OPA1,CLDN11,PAX6,PCDH9,PDE4B,ENPP2,ZDHHC8,ABCB1,NLGN3,SEMA5B,TMIE,RETREG1,GPSM2,PLEC,PLXNB1,PMP22,MBOAT7,FA2H,POLG,PRKACB,PRPH,RELN,KLK6,LAMA1,PTCH1,PTPN13,PEX2,SH3TC2,KHDRBS2,RDX,CRTAC1,RET,PRRT2,RFX3,KIF7,RIC8B,ROBO1,ROBO2,RORB,FBXW7,GLDN,LRRK2,RXRA,STX1B,ATXN2,ATXN7,SCN8A,SH3GL3,ARX,CPEB3,FUZ,NLGN1,SLC4A3,PREX2,SLC6A8,SIRT2,CCDC88A,SLC12A2,NAPB,TET1,CPEB4,SMARCC2,IFT122,SNCA,MBD5,MYO16,SPATA7,SOX11,SP2,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,NFASC,CLSTN2,SSTR1,SSTR2,ERBIN,STAU1,ELOVL4,SEPT8,STX1A,SULF2,STXBP1,SYNE2,ARHGEF9,PLCB1,SYN1,SYN2,MTCL1,CAMTA1,AGTPBP1,ATMIN,CUX2,ZEB1,TRIM2,USP22,SYNE1,SLC19A3,SIRT1,ZNF106,THRA,ENHO,HEY1,TLR4,NR2E1,TP53BP2,CDK20,WBP2,NR2C2,TRIO,TSC1,TSC2,UBE3A,UCHL1,UGT8,VGF,VLDLR,LGI4,ZIC2,ZNF24,TRIM9,ELFN1,CRB2,REEP1,DPYSL5,SPIRE1,SLC30A3,MAP3K12,GDPD5,PRDM8,TUBA1A,SLC17A7,PDSS2,EPM2A,RTN4,GJC2,MSRB3,NETO1,ST8SIA2,GAN" Mouse Phenotype MP:0002206 abnormal CNS synaptic transmission 2.36E-17 1.71E-13 4.28E-14 4.05E-13 187 681 "SYN3,ASIC1,ADCY8,ADD2,ADORA1,ADRA1D,LRFN2,MTA3,SEMA6A,DOC2A,APBA2,MADD,ARRB1,CADPS,ASPA,CHRD,TMEM108,ATP1A3,ATP2A2,ATP2B2,ADGRB3,RGS9,KSR1,SYNJ1,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB2,KALRN,CAMK2A,CAMK2B,CBLN1,CCK,DLGAP2,CACNA2D2,CHRNA4,PLAA,CLCN3,ARHGEF6,CNR1,PICK1,AKAP5,ZNF521,CRMP1,ERC2,CYBB,ARHGAP32,DGKB,DAPK1,KIAA0319,LYPD1,PLPPR4,SNAP91,SV2B,GRIN3A,DNM1,SHANK1,SLC12A6,DPP6,SEZ6L2,EDNRA,MBNL2,EGR3,TMEM35A,ENO2,ERBB2,ERBB4,ADGRV1,EZH1,NRN1,CLVS1,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,FOXO3,NBEA,PDLIM5,CAMKK2,CSPG5,FYN,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,DISC1,CPLX2,CPLX1,PCDH17,DCLK2,GPR37,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRM2,GRM8,FRMD5,ACOT7,SYNPO,IRF8,LRRTM1,ITPKA,KIF5A,STXBP5,L1CAM,LAMA2,MAP6,MAPT,MAT2A,MBD1,MBP,MEF2C,AFDN,GIT1,MYO5A,NELL2,NOVA2,NRCAM,NTRK2,IGSF11,OPRL1,PAX6,PCDH9,PDE4B,TMOD2,ZDHHC8,NLGN3,PPP1R1A,PRKACB,PRKAR1B,MAPK3,MAPK9,SLC26A11,RELN,PTN,RASGRF1,PRRT2,KCNIP3,STX1B,RYR3,ATXN7,SH3GL3,CPEB3,NLGN1,CCDC88A,NAPB,SNAP25,SP4,SST,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,TCF4,AP4E1,ICAM5,RIMBP2,TSC1,TSC2,UBE3A,UCHL1,VGF,VLDLR,ZIC2,ELFN1,CELF4,DPYSL5,ANKS1B,RNF103,SLC17A7,KCNAB1,FZD3,NETO2,NETO1,JPH3" Mouse Phenotype MP:0001399 hyperactivity 1.01E-16 7.34E-13 1.47E-13 1.39E-12 145 488 "PTCHD1,AGT,SORCS2,C1QTNF1,ABCD2,UNC79,APAF1,ASPA,MARK4,CHRD,ATP1A3,ADGRB2,CACNA1G,CACNA1B,DDR1,KALRN,CAMK2A,USP2,DLGAP2,CACNA2D2,CHN1,CLCN3,CNR1,WHRN,COX4I1,ZNF521,CLOCK,CREM,NCOR1,ABCG1,PDE4DIP,CNTNAP2,APPL1,HDAC4,DGKB,BRINP1,SNAP91,SLC12A6,RCAN1,EIF4G2,MRNIP,TMEM35A,ENO2,RCAN2,ERBB4,NCALD,PPP1R1B,FGF12,FGF13,FGF14,KHDRBS3,GABBR1,GABRA3,GABRB3,GABRG2,GALC,DISC1,CPLX2,PPARGC1A,GLUL,GNAL,GNAO1,MCHR1,TPPP,GRIA2,PARD3B,ATE1,GRM2,GSTM5,FRMD5,VSIG4,ACOT7,KCNB1,L1CAM,LSAMP,MAP6,MAPT,ADAM11,MMP16,MOV10,GIT1,MYO5A,MYO6,MYO7A,NTRK2,OXTR,PCDH9,PDE1B,TMOD2,NLGN3,SH3KBP1,KANSL1,MAPK3,PTPRG,PRRT2,RGS4,LRRK2,KCNIP3,RYR3,SATB1,ATXN2,ARX,FBXO11,WDR47,SLC6A8,SIRT2,SLC12A2,SNAP25,SNCA,ANKFN1,SP4,TSPYL2,CLSTN2,ITPRID2,SST,STX1A,PLCB1,TACR1,ADGRL3,ATMIN,TCF4,ZEB1,SIRT1,AP4E1,AKTIP,SLC44A1,THRA,CSMD1,WBP2,TSC1,TST,UCHL1,TOM1L2,VGF,VLDLR,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,ANKS1B,FTSJ1,TUBA1A,IFT88,AP3B2" Mouse Phenotype MP:0001392 abnormal locomotor behavior 2.07E-16 1.50E-12 2.51E-13 2.37E-12 354 1581 "ABR,ACHE,ADCY5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,C1QTNF1,ABCD2,UNC79,ALK,AMPD2,AMPD3,OGT,APAF1,APBA2,APC,PRX,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,NUMB,CCAR2,ATP1A1,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADAM23,ADGRB2,RGS9,HCN2,BCS1L,BID,PROM1,SYNJ1,MTMR2,CACNA1G,MYRF,CA8,CACNA1A,CACNA1B,DDR1,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CAST,CBLN1,USP2,RGN,DLGAP2,CDO1,CACNA2D2,CFL2,CHN1,CHRNA4,PLAA,PPT2,CLCN3,TPP1,QKI,CNR1,CNTN1,WHRN,MAGED1,GAL3ST1,COX4I1,ZNF521,CLOCK,CREM,CRY2,NCOR1,ABCG1,CSF1R,PDE4DIP,CNTNAP2,APPL1,CTH,CYBB,GPRASP1,HDAC4,DGKB,DAPK1,BRINP1,DBT,DCTN1,SNAP91,DMD,DNM1,SHANK1,SLC12A6,RCAN1,E2F5,E2F6,EDIL3,EGR3,EIF4G2,COPS4,MRNIP,TMEM35A,ENO2,RCAN2,ERBB2,ERBB4,ERCC2,NCALD,APC2,ETV1,PIPOX,F5,FDFT1,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,FGFR1,FGFR3,SUCO,FOXO3,FLNC,NBEA,PDLIM5,FAM49B,KHDRBS3,BRSK1,FYN,GAA,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,DISC1,CPLX2,CPLX1,GATM,GCNT2,PPARGC1A,HPGDS,GLI2,GLUL,GNAL,GNAO1,GPT2,MCHR1,GPR37,TPPP,GRIA2,PARD3B,GRIN2C,GRIN2D,ATE1,GRM2,GRM8,CIT,GSTM5,PSIP1,HAS2,NXPH3,FRMD5,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,ZIC5,RBPJ,LRRTM1,ITGA7,ITPKB,KCNB1,L1CAM,LAMA2,LAMP2,LIG4,LSAMP,MAP6,MAPT,MBP,ADAM11,MEF2C,PPM1L,AFF1,MMP16,MN1,MOV10,GIT1,DBNL,MSI1,ADAM22,MYCN,MYO5A,MYO6,MYO7A,MYO9A,NF1,NFIX,NPY,NRCAM,NTRK2,NTRK3,OGG1,OPA1,OXTR,PCDH9,PDE4B,PDE1B,TMOD2,NLGN3,TMIE,PLCB2,PCDH18,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,KANSL1,PRKAB2,MAPK3,EPDR1,HYDIN,RELN,LAMA1,PTCH1,PTPRG,PEX2,OXR1,KHDRBS2,RET,PRRT2,FIGN,RGS4,ROBO2,RORB,GLDN,LRRK2,KCNIP3,STX1B,RYR3,SATB1,ATXN2,ATXN7,SCN8A,ARX,CPEB3,FBXO11,SLC4A3,PREX2,WDR47,SLC6A8,SIRT2,CCDC88A,SLC12A2,NAPB,SNAP25,SNCA,KIF13A,ANKFN1,SP4,ZNF423,TSPYL2,NFASC,CLSTN2,ITPRID2,SST,SSTR1,SSTR2,STAU1,ELOVL4,SEPT8,STX1A,STXBP1,VPS13A,PLCB1,SYPL1,TACR1,CAMTA1,ADGRL3,AGTPBP1,IQCE,ATMIN,TCF4,ZEB1,TRIM2,USP22,SLC19A3,DICER1,SIRT1,CHST8,AP4E1,ZNF106,AKTIP,SLC44A1,THRA,ENHO,NACC2,TK2,TLR4,CSMD1,TP53BP2,RASD2,WBP2,TRIO,TSC1,TSC2,TST,UBE3A,UCHL1,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,WNT7A,LGI4,ZIC1,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,REEP1,ANKS1B,FTSJ1,TUBA1A,PDSS2,EPM2A,GJC2,RNF170,AAAS,FXR1,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0001516 abnormal motor coordination/balance 5.99E-16 4.35E-12 6.22E-13 5.89E-12 218 858 "ABR,ACHE,ADCY5,ADRA1D,ABCD2,PKP4,APBA2,GAS7,PRX,SPTBN4,ARNTL,ASPA,NCOA1,NUMB,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADAM23,BBS2,RGS9,HCN2,BID,PROM1,BMP7,SYNJ1,MTMR2,SGCE,CACNA1I,CACNA1G,WASF1,MYRF,CA8,CACNA1A,CACNB4,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CBLN1,CERS5,CACNA2D2,CFL2,CHN1,PLAA,PPT2,CLCN3,TPP1,QKI,CNR1,CNTN1,WHRN,AKAP5,GAL3ST1,IGDCC3,PREPL,HAPLN1,CSF1R,CNTNAP2,CYBB,ARHGAP32,SNPH,BRINP1,DMD,DNM1,SHANK1,SLC12A6,DTNA,DTNB,E2F5,E2F6,EDIL3,SEZ6L2,CELSR3,MBNL2,EGR3,ERBB2,ERCC2,APC2,ETV1,FDFT1,PRMT5,FGF12,FGF14,FGFR1,SUCO,AP4B1,GAA,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,SRRM4,CPLX2,CPLX1,PPARGC1A,HPGDS,GLI2,GNAO1,GPR37,GRIA2,GRIN2C,GRM2,GRM8,CIT,NXPH3,ACOT7,KCNK3,KIF5A,L1CAM,LAMA2,LIG4,LSAMP,MAPT,MBNL1,MBP,ADAM11,PPM1L,AFF1,GIT1,DBNL,MSI1,ADAM22,MYO5A,MYO6,MYO7A,NF1,NFIX,NOVA1,NRCAM,NTRK2,NTRK3,OPA1,CLDN11,PCDH9,TMOD2,NLGN3,TMIE,PLCL1,JAKMIP1,PMP22,FA2H,MAPK10,SLC26A11,HYDIN,RELN,LAMA1,PTCH1,PTPRG,PEX2,OXR1,PRRT2,FIGN,RGS4,RORB,EPHA10,GLDN,LRRK2,STX1B,ATXN2,ATXN7,SCN8A,ARX,PREX2,SLC6A8,SIRT2,SLC12A2,NAPB,CPEB4,SNAP25,SNCA,MBD5,ANKFN1,SP4,ZNF423,NFASC,SSTR2,STXBP1,VPS13A,TACR1,MTCL1,CAMTA1,AGTPBP1,TRIM2,SYNE1,ZNF106,THRA,ENHO,MTMR14,TLR4,RASD2,NR2C2,TRIO,TSN,TSC1,TSC2,UBE3A,UCHL1,UGT8,VLDLR,CLIP2,LGI4,ZIC1,ELFN1,SLC30A4,PRDM8,RNF103,SLC17A7,PDSS2,EPM2A,GJC2,RNF170,AAAS,JPH3" Mouse Phenotype MP:0003491 abnormal voluntary movement 3.10E-15 2.25E-11 2.82E-12 2.67E-11 370 1698 "ABR,ACHE,ADCY5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,C1QTNF1,ABCD2,UNC79,ALK,AMPD2,AMPD3,OGT,APAF1,APBA2,APC,PRX,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,NUMB,CCAR2,ATP1A1,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADAM23,ADGRB2,RGS9,HCN2,BCS1L,BID,PROM1,SYNJ1,MTMR2,CACNA1G,MYRF,CA8,CACNA1A,CACNA1B,DDR1,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CAST,CBLN1,USP2,RGN,CD86,DLGAP2,CDO1,CACNA2D2,CFL2,CHN1,CHRNA4,PLAA,PPT2,CLCN3,TPP1,QKI,CNR1,CNTN1,WHRN,MAGED1,GAL3ST1,COX4I1,ZNF521,CLOCK,CREM,CRY2,NCOR1,NCOR2,ABCG1,CSF1,CSF1R,PDE4DIP,CNTNAP2,APPL1,CTH,CYBB,GPRASP1,HDAC4,DGKB,DAPK1,BRINP1,DBT,DCTN1,SNAP91,DMD,DNM1,SHANK1,SLC12A6,RCAN1,E2F5,E2F6,EDIL3,EGR3,EIF4G2,COPS4,MRNIP,TMEM35A,ENO2,RCAN2,ERBB2,ERBB4,ERCC2,NCALD,APC2,ETV1,PIPOX,EYA1,F5,FDFT1,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,FGFR1,FGFR3,SUCO,FOXO3,FLNC,NBEA,PDLIM5,FAM49B,KHDRBS3,DLL3,BRSK1,FYN,GAA,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,DISC1,SRRM4,CPLX2,CPLX1,GATM,GCNT2,PPARGC1A,HPGDS,GLI2,GLUL,GNAL,GNAO1,GPT2,MCHR1,GPR37,TPPP,GRIA2,PARD3B,GRIN2C,GRIN2D,ATE1,GRM2,GRM8,CIT,GSTM5,PSIP1,HAS2,NXPH3,FRMD5,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,ZIC5,RBPJ,IL6R,LRRTM1,ITGA7,ITPKB,KCNB1,KIF5A,L1CAM,LAMA2,LAMP2,LIG4,LSAMP,MAP6,MAPT,MBP,ADAM11,MEF2C,PPM1L,AFF1,MMP16,MN1,MOV10,GIT1,DBNL,MSI1,ADAM22,MYCN,MYO5A,MYO6,MYO7A,MYO9A,NEFH,NF1,NFIX,NPY,NRCAM,NTRK2,NTRK3,OGG1,OPA1,OXTR,PCDH9,PDE4B,PDE1B,TMOD2,NLGN3,TMIE,PLCB2,PCDH18,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,KANSL1,PRKAB2,MAPK3,EPDR1,MAPK7,HYDIN,RELN,LAMA1,PTCH1,PTPRG,PEX2,SH3TC2,OXR1,KHDRBS2,RET,PRRT2,FIGN,RGS4,ROBO2,RORB,GLDN,LRRK2,KCNIP3,STX1B,RYR3,SATB1,ATXN2,ATXN7,SCN8A,ARX,CPEB3,FBXO11,SLC4A3,PREX2,WDR47,SLC6A8,SIRT2,CCDC88A,SLC12A2,NAPB,SNAP25,MAPKBP1,SNCA,KIF13A,ANKFN1,SNRPN,SP4,NMNAT2,ZNF423,TSPYL2,NFASC,CLSTN2,ITPRID2,SST,SSTR1,SSTR2,STAU1,ELOVL4,SEPT8,STX1A,STXBP1,VPS13A,PLCB1,SYPL1,TACR1,CAMTA1,ADGRL3,AGTPBP1,IQCE,ATMIN,TCF4,ZEB1,TRIM2,USP22,SLC19A3,DICER1,SIRT1,CHST8,AP4E1,GPR161,ZNF106,AKTIP,SLC44A1,THRA,ENHO,NACC2,TK2,TLR4,CSMD1,TP53BP2,RASD2,WBP2,TRIO,TSC1,TSC2,TST,UBE3A,UCHL1,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,WNT7A,LGI4,ZIC1,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,REEP1,ANKS1B,FTSJ1,TUBA1A,PDSS2,EPM2A,GJC2,RNF170,AAAS,FXR1,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0002063 abnormal learning/memory/conditioning 3.72E-15 2.71E-11 3.01E-12 2.85E-11 185 703 "SYN3,ASIC1,ADCY8,ADD2,FZD9,ADORA2A,PTCHD1,ADRA1D,ADRA1B,LRFN2,KCTD16,DOC2A,AMPH,APBA2,KCNAB2,CDC14B,CHRD,NCOA1,TMEM108,ATP1A1,ATP1A3,STX16,ADGRB3,RGS9,BCL7A,KSR1,SGCE,CACNA1G,WASF1,CA8,CACNA1B,KALRN,CAMK2A,CAMK2B,CAST,DLGAP2,CHRNA4,TAOK2,CLCN3,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRMP1,NCOR1,CSF1R,CNTNAP2,ERC2,CYBB,ARHGAP32,DGKB,BRINP1,DBN1,LYPD1,SHANK1,SLC12A6,RCAN1,EDIL3,MBNL2,TMEM35A,ENO2,RCAN2,ERBB4,ERCC2,NRN1,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,FYN,GABBR1,CHL1,GABRB3,GABRG2,IP6K3,DISC1,CPLX2,GHR,MCHR1,GRIA2,GRIN2C,GRM8,NXPH3,SYNPO,CPT1C,LRRTM1,L1CAM,LSAMP,MAP2,MAPT,MBD1,MBP,ADAM11,GIT1,MYO5A,IDNK,NF1,NPY,NPTX2,NRCAM,NTRK2,OPA1,OPRL1,OXTR,PCDH9,PDE4B,PDE1B,GPR85,TMOD2,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,FA2H,SH3KBP1,PRKACB,PKIA,PRKCB,MAPK3,RELN,PTPRG,RASGRF1,RGS4,CARF,RORB,ZC3H14,KCNIP3,RYR3,ARX,CPEB3,SLC6A8,CCDC88A,MTERF2,TET1,SNAP25,MBD5,ANKFN1,SP4,CLSTN2,SST,SSTR2,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,TACR1,TAF6,WSCD1,TCF4,DMXL2,CRTC1,SLC44A1,THRA,ICAM5,NR2E1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,NDRG4,ZNF142,SPIRE1,GDPD5,RNF103,TUBA1A,SLC17A7,KCNAB1,EPM2A,FZD3,GJC2,AAAS,NETO1,ST8SIA2,JPH3" Mouse Phenotype MP:0014114 abnormal cognition 4.33E-15 3.14E-11 3.14E-12 2.98E-11 185 704 "SYN3,ASIC1,ADCY8,ADD2,FZD9,ADORA2A,PTCHD1,ADRA1D,ADRA1B,LRFN2,KCTD16,DOC2A,AMPH,APBA2,KCNAB2,CDC14B,CHRD,NCOA1,TMEM108,ATP1A1,ATP1A3,STX16,ADGRB3,RGS9,BCL7A,KSR1,SGCE,CACNA1G,WASF1,CA8,CACNA1B,KALRN,CAMK2A,CAMK2B,CAST,DLGAP2,CHRNA4,TAOK2,CLCN3,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRMP1,NCOR1,CSF1R,CNTNAP2,ERC2,CYBB,ARHGAP32,DGKB,BRINP1,DBN1,LYPD1,SHANK1,SLC12A6,RCAN1,EDIL3,MBNL2,TMEM35A,ENO2,RCAN2,ERBB4,ERCC2,NRN1,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,FYN,GABBR1,CHL1,GABRB3,GABRG2,IP6K3,DISC1,CPLX2,GHR,MCHR1,GRIA2,GRIN2C,GRM8,NXPH3,SYNPO,CPT1C,LRRTM1,L1CAM,LSAMP,MAP2,MAPT,MBD1,MBP,ADAM11,GIT1,MYO5A,IDNK,NF1,NPY,NPTX2,NRCAM,NTRK2,OPA1,OPRL1,OXTR,PCDH9,PDE4B,PDE1B,GPR85,TMOD2,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,FA2H,SH3KBP1,PRKACB,PKIA,PRKCB,MAPK3,RELN,PTPRG,RASGRF1,RGS4,CARF,RORB,ZC3H14,KCNIP3,RYR3,ARX,CPEB3,SLC6A8,CCDC88A,MTERF2,TET1,SNAP25,MBD5,ANKFN1,SP4,CLSTN2,SST,SSTR2,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,TACR1,TAF6,WSCD1,TCF4,DMXL2,CRTC1,SLC44A1,THRA,ICAM5,NR2E1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,NDRG4,ZNF142,SPIRE1,GDPD5,RNF103,TUBA1A,SLC17A7,KCNAB1,EPM2A,FZD3,GJC2,AAAS,NETO1,ST8SIA2,JPH3" Mouse Phenotype MP:0002152 abnormal brain morphology 1.26E-13 9.18E-10 8.34E-11 7.90E-10 373 1755 "ABR,ACHE,ADD1,AXIN2,FZD9,LRFN2,PCDH19,AGT,NME5,SORCS2,CC2D2A,SPARCL1,SEMA6A,ABCD2,PCDH10,BBOX1,ALK,AMT,SEMA7A,APAF1,APBB2,APC,SEMA4G,PRX,SPTBN4,CADPS,ASPA,CHRD,NCOA1,NUMB,DYNLL1,TMEM108,ATP1A3,ATP2B2,BBS2,RGS9,NRP2,BID,BMP7,FUBP1,SGCE,CACNA1G,WASF1,CA8,CACNA1A,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CBLN1,KRIT1,RGN,ARHGEF2,CDH2,DCLK1,ARHGAP33,NOG,NUMBL,CACNA2D2,COPB2,ASIC3,CHN1,CHN2,CHRNA4,NDST3,SLIT2,LHX2,PLAA,PPT2,CLCN3,TPP1,QKI,HECTD1,CNGA3,CNN3,CNR1,CNTFR,CNTN1,GAL3ST1,COX4I1,ZNF521,CLOCK,AKAP12,CRMP1,NCOR1,NCOR2,AATK,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,SLITRK5,PYGO1,CYBB,BOC,HDAC4,DGKB,BRINP1,DBN1,PLPPR4,KIF19,DMD,DNM1,NYAP1,MED12,SLC29A4,CDON,SHANK1,SLC12A6,DPYSL2,PDCD6IP,DNM1L,E2F5,E2F6,EBF1,EDIL3,EDNRB,CELSR3,APH1A,EGFR,EMX2,ENO2,EPB41L2,COQ7,EPHB1,ERBB4,ERCC2,APC2,EYA1,TUBB3,DLC1,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,VTI1B,EVL,NBEA,TMEM107,SMC2,AK8,STAMBP,ATP2C1,DLL3,AP4B1,BRSK1,FYN,MEGF10,CHL1,GABRB3,GAD1,GALC,B4GALNT1,IP6K3,DISC1,SRRM4,CPLX2,GDF1,FREM1,GHR,PPARGC1A,GLI2,GLUL,KDM2B,DCLK2,GPT2,PRRC2B,GPR37,GRIA2,GRIN2C,ATE1,CIT,HLF,SYNPO,DHX35,HSF2,IGF1,ZIC5,LRRCC1,IL6ST,INSM1,LRRTM1,KCNQ3,KIF2A,KIT,L1CAM,LAMA2,LAMP2,STMN1,LIFR,LIG4,SYTL4,SMAD1,SMAD9,MAP2,MAPT,MBD1,MBP,MEF2C,KITLG,PPM1L,AFF1,AFDN,MSI1,BLOC1S2,MYCN,MYO5A,MYO9A,NCAM2,NDP,NEK1,NF1,NFIX,SLC11A2,NRCAM,NTRK2,OPA1,OXTR,PAX6,PCDH9,PDE4B,ENPP2,PDPK1,GPR85,ABCB1,NLGN3,PIK3C2A,PKD1,JAKMIP1,PLXNB1,PSAT1,MBOAT7,FA2H,PPP3CA,PRKACB,CEP41,MAPK7,MAPK9,HYDIN,RELN,LAMA1,PTCH1,PTH1R,PTK2,PEX2,CCDC40,KHDRBS2,CRTAC1,RET,PRRT2,FIGN,RGS4,KIF7,RIC8B,SETD5,ROBO1,ROBO2,FBXW7,ZC3H14,LRRK2,ATAT1,RXRA,SALL1,SATB1,ATXN2,ATXN7,SCN8A,SMPD3,KIF27,ARX,CPEB3,FUZ,AMBRA1,PREX2,EPN2,SLC6A8,SIRT2,CCDC88A,TET1,SMARCA4,SMARCC2,CDK5RAP2,IFT122,SNAP25,SNCA,MBD5,PDZRN3,MYO16,SOX3,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,SPTB,NFASC,TTBK2,SULF2,STXBP1,JMJD6,VPS13A,PLCB1,SYN1,SYN2,COBL,MTCL1,CAMTA1,MLST8,AGTPBP1,MGRN1,ATMIN,TCF4,DMXL2,CUX2,ZEB1,TRIM2,RPGRIP1L,TCF12,USP22,TEK,SIRT1,AP4E1,GPR161,THRA,ENHO,TIAM1,HEY1,TK2,NR2E1,PARD3,TP53BP2,CDK20,TRIO,TSC1,TSC2,HIRA,UBE3A,UCHL1,UGT8,TOM1L2,VLDLR,CLIP2,XRCC4,ZBTB14,ZIC1,ZIC2,ZNF24,TRIM9,CRB2,SPHK2,CELF4,DPYSL5,SLC30A3,MAP3K12,PRDM8,TUBA1A,SEMA3B,PDSS2,EPM2A,FZD3,UBE3B,GJC2,IFT88,ST8SIA2" Mouse Phenotype MP:0002064 seizures 1.38E-13 1.00E-09 8.35E-11 7.90E-10 116 390 "SYN3,ACHE,FZD9,ADORA1,ADORA2A,AMPH,KCNAB2,NUMB,ATP1A3,HCN2,NRP2,BID,SYNJ1,SGCE,CACNA1G,C5,MYRF,BAIAP3,CACNA1A,CACNB4,CAMK2A,P2RX6,SYNGR3,NUMBL,CACNA2D2,CHN1,CHRNA4,CLCN3,TPP1,QKI,CNR1,AKAP5,CREM,CNTNAP2,ARHGAP32,HDAC4,PLPPR4,SNAP91,SV2B,DNM1,DMTF1,SLC12A6,EDIL3,MBNL2,APC2,ADGRV1,FGF13,FGF14,FYN,GABBR1,GABRB3,GABRG2,GALC,B4GALNT1,CPLX1,GFRA2,PPARGC1A,KCNMB4,DCLK2,GNAO1,TPPP,GRIA2,GRIK4,GRIK5,ATE1,CIT,HLF,KCNQ3,KIF5A,MAPT,MBP,DBNL,ADAM22,MYO5A,NF1,NPY,NTRK2,SLC10A4,PLCL1,PMP22,MAPK10,FITM2,PTPRO,PRRT2,KCNIP1,STX1B,ATXN7,SCN2B,SCN8A,SH3GL3,ARX,ST8SIA1,SLC4A3,SLC6A11,NAPB,SNAP25,FAIM2,SST,PLCB1,SYN1,SYN2,SYP,TRIM2,TCF12,SZT2,TSC1,TSC2,UBE3A,ZNF24,ELFN1,CELF4,EPM2A,GJC2,NETO1,AP3B2,GAN" Mouse Phenotype MP:0002572 abnormal emotion/affect behavior 2.88E-13 2.09E-09 1.61E-10 1.52E-09 170 657 "SYN3,ADCY8,ADORA1,ADORA2A,PTCHD1,ADRA1B,LRFN2,MTA3,ALK,APBA2,ASPA,CHRD,ATP1A1,ATP1A3,STX16,ADGRB2,BBS2,RGS9,BCL7A,HCN2,WASF1,BAIAP3,CACNA1B,DDR1,CACNB4,KALRN,HAP1,CAMK2A,CAMK2B,DLGAP2,DLGAP1,CHRNA4,NDST3,CLCN3,QKI,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRHBP,NCOR1,CSF1R,CNTNAP2,SLITRK5,ERC2,ARHGAP32,DGKB,BRINP1,KIAA0319,LYPD1,SNAP91,NR1D2,SHANK1,SLC12A6,TMEM35A,HSD17B14,ENO2,ERBB4,ERCC2,FGF12,FGF13,FGF14,PDLIM5,FYN,GABBR1,CHL1,GABRB3,GABRG2,DISC1,CPLX2,PCDH17,PPARGC1A,DHRS4,GLUL,GNAL,MCHR1,TPPP,GRIA2,GRM2,GRM8,FAM19A2,SYNPO,HNF4G,HNMT,IL6R,LRRTM1,L1CAM,LAMA2,LSAMP,MAP2,MAP6,MAPT,MOV10,GIT1,MYO7A,NPY,NTRK2,OPA1,OPRL1,OXTR,P2RX7,PDE4B,PDE1B,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,SH3KBP1,PKIA,HYDIN,PTCH1,PTPRG,RGS4,RORB,ATAT1,KCNIP3,RYR3,SCN8A,ARX,CPEB3,SLC6A8,CCDC88A,EPC1,SNAP25,MBD5,KIF13A,SP4,SSTR2,STX1A,ARHGEF9,DNAJC9,SYN1,ARC,SYN2,TACR1,TAF6,ADGRL3,ATMIN,WSCD1,TCF4,DMXL2,ZEB1,CRTC1,SLC44A1,THRA,NR2E1,CSMD1,RASD2,NR2C2,TRPM2,TSN,TSC1,TSC2,UBE3A,UCHL1,TOM1L2,ZIC2,ELFN1,ZNF142,GDPD5,RNF103,TUBA1A,SLC17A7,FZD3,AAAS,ST8SIA2,JPH3" Mouse Phenotype MP:0000787 abnormal telencephalon morphology 8.70E-13 6.32E-09 4.51E-10 4.27E-09 209 867 "ACHE,FZD9,LRFN2,AGT,SORCS2,SEMA6A,PCDH10,SEMA7A,APAF1,APBB2,APC,PRX,SPTBN4,CADPS,ASPA,CHRD,NUMB,TMEM108,ATP1A3,ATP2B2,BBS2,RGS9,NRP2,BID,FUBP1,WASF1,KALRN,HAP1,PTBP2,CAMK2A,CDH2,DCLK1,ARHGAP33,NOG,NUMBL,COPB2,CHN1,CHN2,SLIT2,LHX2,PLAA,PPT2,CLCN3,QKI,CNGA3,CNR1,ZNF521,CLOCK,CRMP1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,SLITRK5,DGKB,BRINP1,DBN1,CDON,SHANK1,SLC12A6,DPYSL2,PDCD6IP,E2F5,EBF1,EDIL3,CELSR3,APH1A,EGFR,EMX2,ENO2,EPHB1,APC2,TUBB3,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,VTI1B,EVL,SMC2,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,GAD1,GALC,DISC1,SRRM4,CPLX2,PPARGC1A,GLI2,DCLK2,GPT2,GRIA2,CIT,SYNPO,DHX35,HSF2,IGF1,ZIC5,IL6ST,LRRTM1,KCNQ3,KIF2A,KIT,L1CAM,LAMA2,LIG4,MAP2,MAPT,MBD1,MBP,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,MYO9A,NCAM2,NEK1,NF1,NFIX,NTRK2,OPA1,PAX6,PCDH9,ABCB1,PKD1,JAKMIP1,PLXNB1,MBOAT7,PPP3CA,MAPK9,HYDIN,RELN,PTCH1,PEX2,CRTAC1,PRRT2,RGS4,RIC8B,SETD5,ROBO1,ROBO2,FBXW7,ZC3H14,LRRK2,ATAT1,SALL1,ARX,CPEB3,FUZ,AMBRA1,SLC6A8,CCDC88A,TET1,SMARCC2,CDK5RAP2,SNAP25,SNCA,SOX3,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,VPS13A,PLCB1,SYN1,MLST8,AGTPBP1,CUX2,ZEB1,RPGRIP1L,USP22,AP4E1,THRA,HEY1,NR2E1,PARD3,TP53BP2,TRIO,TSC1,TSC2,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,TRIM9,SLC30A3,MAP3K12,PRDM8,TUBA1A,EPM2A,FZD3,UBE3B,IFT88,ST8SIA2" Mouse Phenotype MP:0002272 abnormal nervous system electrophysiology 2.11E-12 1.54E-08 1.02E-09 9.69E-09 105 353 "SYN3,ADCY8,ADORA1,PTCHD1,PCDH19,SEMA6A,ABCD2,KCNAB2,PRX,MADD,ATP1A3,ATP2B2,ADGRB3,RGS11,HCN2,BID,MTMR2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,CALB2,KALRN,CD86,ENTPD2,CACNA2D2,ASIC3,CHN1,CHRNA4,STOML1,WHRN,CLOCK,CNTNAP2,SNAP91,GRIN3A,DNM1,SLC12A6,DPP6,EGR3,EMX2,GPHN,ERBB2,ETV1,FGF14,FGFR1,GABBR1,GABRG2,GAD1,KCNMB4,MCHR1,GRIA2,GRIK4,GSN,HLF,IL6ST,KCNJ16,KCNK3,KCNN3,KCNQ3,KIT,LAMA2,STMN1,MBP,GIT1,MYO6,MYO7A,NEFH,NRCAM,NALCN,PLCL1,JAKMIP1,PLEC,PMP22,SLC26A11,SH3TC2,GLDN,LRRK2,SCN2B,SCN8A,ARX,SIRT2,NFASC,SST,SSTR1,SSTR2,ERBIN,SEPT8,SYN1,ARC,SYN2,TACR1,TCF4,SIK3,TRPM2,TSC1,UBE3A,UGT8,KCNT2,ELFN1,SLC17A7,KCNAB1,EPM2A,JPH3" Mouse Phenotype MP:0003313 abnormal locomotor activation 3.47E-12 2.52E-08 1.58E-09 1.49E-08 265 1182 "ADCY5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,C1QTNF1,ABCD2,UNC79,ALK,APAF1,APBA2,APC,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,CCAR2,ATP1A1,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADGRB2,RGS9,HCN2,BCS1L,CACNA1G,CACNA1A,CACNA1B,DDR1,CACNB4,KALRN,HAP1,CAMK2A,USP2,DLGAP2,CDO1,CACNA2D2,CFL2,CHN1,CHRNA4,PLAA,CLCN3,TPP1,QKI,CNR1,WHRN,MAGED1,COX4I1,ZNF521,CLOCK,CREM,CRY2,NCOR1,ABCG1,PDE4DIP,CNTNAP2,APPL1,CTH,CYBB,GPRASP1,HDAC4,DGKB,BRINP1,DBT,SNAP91,DMD,SHANK1,SLC12A6,RCAN1,EIF4G2,COPS4,MRNIP,TMEM35A,ENO2,RCAN2,ERBB2,ERBB4,NCALD,PIPOX,F5,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,FOXO3,FLNC,NBEA,PDLIM5,FAM49B,KHDRBS3,BRSK1,GAA,GABBR1,GABRA3,GABRB3,GABRG2,GALC,DISC1,CPLX2,GATM,GCNT2,PPARGC1A,GLI2,GLUL,GNAL,GNAO1,GPT2,MCHR1,GPR37,TPPP,GRIA2,PARD3B,GRIN2C,GRIN2D,ATE1,GRM2,GSTM5,PSIP1,FRMD5,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,RBPJ,LRRTM1,ITPKB,KCNB1,L1CAM,LAMP2,LSAMP,MAP6,MAPT,MBP,ADAM11,MMP16,MN1,MOV10,GIT1,MYCN,MYO5A,MYO6,MYO7A,NPY,NRCAM,NTRK2,OGG1,OXTR,PCDH9,PDE4B,PDE1B,TMOD2,NLGN3,PLCB2,PCDH18,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,KANSL1,PRKAB2,MAPK3,EPDR1,HYDIN,RELN,PTPRG,PEX2,KHDRBS2,RET,PRRT2,RGS4,LRRK2,KCNIP3,RYR3,SATB1,ATXN2,ATXN7,SCN8A,ARX,CPEB3,FBXO11,SLC4A3,PREX2,WDR47,SLC6A8,SIRT2,CCDC88A,SLC12A2,SNAP25,SNCA,KIF13A,ANKFN1,SP4,TSPYL2,NFASC,CLSTN2,ITPRID2,SST,SSTR1,SSTR2,STAU1,ELOVL4,SEPT8,STX1A,VPS13A,PLCB1,SYPL1,TACR1,ADGRL3,IQCE,ATMIN,TCF4,ZEB1,SLC19A3,DICER1,SIRT1,CHST8,AP4E1,ZNF106,AKTIP,SLC44A1,THRA,ENHO,TK2,CSMD1,RASD2,WBP2,TSC1,TSC2,TST,UBE3A,UCHL1,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,ZIC1,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,ANKS1B,FTSJ1,TUBA1A,GJC2,AAAS,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0008415 abnormal neurite morphology 1.00E-11 7.29E-08 4.29E-09 4.06E-08 124 452 "LRFN2,SORCS2,SEMA6A,ABCD2,PRX,SPTBN4,CADPS,NUMB,TMEM108,NRP2,CACNA1A,KALRN,HAP1,CAMK2A,CD86,SEPT7,DCLK1,ARHGAP33,DLGAP2,CACNA2D2,SLIT2,PLAA,QKI,TMEM184B,ARHGEF6,CNTN1,GAL3ST1,CRMP1,AATK,CSF1,VCAN,PLXNA4,SNPH,DBN1,GRIN3A,DNM1,NYAP1,SLC12A6,DPYSL2,DRP2,DNM1L,EDIL3,EPHB1,ERBB2,NRN1,FGF13,EVL,CAMKK2,GABBR1,CHL1,GABRB3,GALC,IP6K3,SRRM4,GRIK4,CPT1C,ZIC5,LRRTM1,KIF2A,L1CAM,MAPT,MBP,PPM1L,MOV10,GIT1,MYO5A,NEFH,NF1,NFE2L2,NRCAM,NTRK2,CLDN11,PCDH9,PDE4B,ZDHHC8,NLGN3,SEMA5B,PLEC,PMP22,MBOAT7,FA2H,PRPH,LAMA1,PTPN13,SH3TC2,KHDRBS2,RET,ROBO1,ROBO2,GLDN,LRRK2,CPEB3,NLGN1,PREX2,CCDC88A,CPEB4,SNCA,MBD5,MYO16,NMNAT2,ZNF423,SPTAN1,NFASC,ERBIN,STAU1,SEPT8,MTCL1,AGTPBP1,TRIM2,ZNF106,THRA,TLR4,TSC1,TSC2,UBE3A,LGI4,ZIC2,ZNF24,ELFN1,DPYSL5,SPIRE1,TUBA1A,SLC17A7,GAN" Mouse Phenotype MP:0001405 impaired coordination 1.27E-11 9.24E-08 5.13E-09 4.86E-08 128 473 "ADCY5,ABCD2,GAS7,PRX,ASPA,NCOA1,ATP1A3,ATP2B2,RGS9,HCN2,BMP7,MTMR2,SGCE,CACNA1G,WASF1,CA8,CACNA1A,CACNB4,CALB2,KALRN,CAMK2B,CBLN1,CACNA2D2,CLCN3,TPP1,QKI,CNR1,AKAP5,IGDCC3,CSF1R,CYBB,ARHGAP32,SNPH,BRINP1,DMD,SHANK1,SLC12A6,DTNA,DTNB,EDIL3,SEZ6L2,CELSR3,MBNL2,ERBB2,APC2,FDFT1,FGF14,FGFR1,AP4B1,GAA,GABRB3,GABRG2,GAD1,B4GALNT1,IP6K3,CPLX2,PPARGC1A,GNAO1,GPR37,GRIA2,GRIN2C,GRM2,NXPH3,ACOT7,KIF5A,L1CAM,MAPT,MBNL1,MBP,ADAM11,PPM1L,DBNL,MYO5A,NF1,NRCAM,NTRK3,OPA1,CLDN11,PCDH9,TMOD2,NLGN3,JAKMIP1,PMP22,FA2H,MAPK10,SLC26A11,RELN,LAMA1,PTPRG,FIGN,RGS4,RORB,ATXN2,ATXN7,SCN8A,ARX,PREX2,SLC6A8,SIRT2,CPEB4,SNAP25,SNCA,MBD5,SP4,NFASC,SSTR2,VPS13A,TACR1,CAMTA1,SYNE1,ZNF106,ENHO,MTMR14,RASD2,NR2C2,TSN,TSC1,TSC2,UBE3A,UCHL1,UGT8,CLIP2,ELFN1,RNF103,SLC17A7,EPM2A,GJC2,JPH3" Mouse Phenotype MP:0008540 abnormal cerebral hemisphere morphology 3.01E-11 2.19E-07 1.15E-08 1.09E-07 161 645 "ACHE,FZD9,LRFN2,AGT,SORCS2,SEMA6A,APAF1,APBB2,SPTBN4,CADPS,NUMB,TMEM108,ATP1A3,ATP2B2,BBS2,NRP2,BID,FUBP1,WASF1,KALRN,HAP1,PTBP2,CAMK2A,CDH2,DCLK1,ARHGAP33,NUMBL,COPB2,CHN1,CHN2,LHX2,PLAA,PPT2,CLCN3,CNR1,ZNF521,CRMP1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,DGKB,BRINP1,DBN1,CDON,SHANK1,SLC12A6,DPYSL2,PDCD6IP,E2F5,EDIL3,CELSR3,EGFR,EMX2,ENO2,EPHB1,APC2,TUBB3,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,VTI1B,SMC2,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,GAD1,GALC,DISC1,SRRM4,CPLX2,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HSF2,ZIC5,LRRTM1,KCNQ3,KIF2A,L1CAM,LIG4,MAP2,MAPT,MBD1,MBP,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,NF1,NFIX,NTRK2,PAX6,PCDH9,ABCB1,PLXNB1,MBOAT7,PPP3CA,MAPK9,HYDIN,RELN,PEX2,PRRT2,RGS4,ROBO1,ROBO2,FBXW7,LRRK2,ATAT1,ARX,CPEB3,SLC6A8,CCDC88A,SMARCC2,CDK5RAP2,SNAP25,SNCA,SOX3,SOX11,SP2,SP4,MYCBP2,ZNF423,PLCB1,SYN1,AGTPBP1,CUX2,RPGRIP1L,USP22,AP4E1,THRA,NR2E1,TP53BP2,TRIO,TSC1,TSC2,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,TRIM9,SLC30A3,MAP3K12,PRDM8,TUBA1A,EPM2A,FZD3,UBE3B,ST8SIA2" Mouse Phenotype MP:0002207 abnormal long term potentiation 6.62E-11 4.81E-07 2.40E-08 2.28E-07 76 238 "ASIC1,ADCY8,ADD2,LRFN2,DOC2A,CHRD,RGS9,KSR1,WASF1,CACNA1B,CALB2,KALRN,CAMK2A,CAMK2B,ARHGEF6,CNR1,AKAP5,CRMP1,CYBB,DGKB,DPP6,MBNL2,TMEM35A,ERBB4,PPP1R1B,FGF14,BAIAP2,NBEA,CAMKK2,FYN,GABBR1,DISC1,CPLX2,GRIA2,GRIK4,SYNPO,LRRTM1,ITPKA,STXBP5,LAMA2,MAPT,MBD1,MEF2C,NELL2,NOVA2,NTRK2,IGSF11,OPRL1,PDE4B,TMOD2,PPP1R1A,PRKACB,PRKAR1B,MAPK3,MAPK9,PTN,RASGRF1,KCNIP3,RYR3,CCDC88A,SP4,STX1A,ARHGEF9,ARC,SYP,TCF4,ICAM5,TSC1,TSC2,UBE3A,VLDLR,ELFN1,SLC17A7,KCNAB1,NETO1,JPH3" Mouse Phenotype MP:0009357 abnormal seizure response to inducing agent 7.42E-11 5.39E-07 2.57E-08 2.43E-07 66 195 "SYN3,FZD9,ADORA1,ADORA2A,AMPH,ATP1A3,HCN2,NRP2,CACNA1G,BAIAP3,CACNA1A,P2RX6,CACNA2D2,CHRNA4,CLCN3,TPP1,CNR1,AKAP5,CREM,CNTNAP2,ARHGAP32,HDAC4,DNM1,SLC12A6,EDIL3,MBNL2,ADGRV1,FGF13,FGF14,FYN,GABBR1,GABRB3,GABRG2,B4GALNT1,GFRA2,GNAO1,GRIK4,GRIK5,CIT,HLF,KCNQ3,MAPT,MBP,NPY,NTRK2,SLC10A4,PLCL1,MAPK10,PTPRO,PRRT2,KCNIP1,SCN2B,SCN8A,ARX,ST8SIA1,SLC4A3,SLC6A11,FAIM2,PLCB1,SYN1,SYN2,SZT2,TSC2,UBE3A,ELFN1,CELF4" Mouse Phenotype MP:0000783 abnormal forebrain morphology 4.98E-10 3.62E-06 1.64E-07 1.56E-06 240 1095 "ACHE,FZD9,LRFN2,PCDH19,AGT,SORCS2,SEMA6A,PCDH10,BBOX1,ALK,SEMA7A,APAF1,APBB2,APC,PRX,SPTBN4,CADPS,ASPA,CHRD,NUMB,TMEM108,ATP1A3,ATP2B2,BBS2,RGS9,NRP2,BID,FUBP1,WASF1,CACNB4,KALRN,HAP1,PTBP2,CAMK2A,CDH2,DCLK1,ARHGAP33,NOG,NUMBL,CACNA2D2,COPB2,CHN1,CHN2,NDST3,SLIT2,LHX2,PLAA,PPT2,CLCN3,QKI,CNGA3,CNR1,ZNF521,CLOCK,CRMP1,NCOR1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,SLITRK5,BOC,DGKB,BRINP1,DBN1,DMD,CDON,SHANK1,SLC12A6,DPYSL2,PDCD6IP,DNM1L,E2F5,EBF1,EDIL3,CELSR3,APH1A,EGFR,EMX2,ENO2,EPHB1,APC2,EYA1,TUBB3,DLC1,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,VTI1B,EVL,NBEA,SMC2,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,GAD1,GALC,DISC1,SRRM4,CPLX2,GDF1,GHR,PPARGC1A,GLI2,DCLK2,GPT2,PRRC2B,GPR37,GRIA2,CIT,SYNPO,DHX35,HSF2,IGF1,ZIC5,IL6ST,INSM1,LRRTM1,KCNQ3,KIF2A,KIT,L1CAM,LAMA2,LAMP2,LIG4,SYTL4,SMAD1,MAP2,MAPT,MBD1,MBP,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,MYO9A,NCAM2,NEK1,NF1,NFIX,NTRK2,OPA1,PAX6,PCDH9,ENPP2,PDPK1,ABCB1,PIK3C2A,PKD1,JAKMIP1,PLXNB1,MBOAT7,PPP3CA,MAPK9,HYDIN,RELN,PTCH1,PEX2,CRTAC1,PRRT2,RGS4,RIC8B,SETD5,ROBO1,ROBO2,FBXW7,ZC3H14,LRRK2,ATAT1,SALL1,SMPD3,ARX,CPEB3,FUZ,AMBRA1,SLC6A8,CCDC88A,TET1,SMARCC2,CDK5RAP2,SNAP25,SNCA,MBD5,SOX3,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,VPS13A,PLCB1,SYN1,MLST8,AGTPBP1,DMXL2,CUX2,ZEB1,RPGRIP1L,USP22,TEK,SIRT1,AP4E1,THRA,TIAM1,HEY1,NR2E1,PARD3,TP53BP2,TRIO,TSC1,TSC2,HIRA,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,TRIM9,SLC30A3,MAP3K12,PRDM8,TUBA1A,EPM2A,FZD3,UBE3B,IFT88,ST8SIA2" Mouse Phenotype MP:0001469 abnormal contextual conditioning behavior 1.10E-09 7.95E-06 3.46E-07 3.27E-06 56 163 "ADCY8,ADD2,PTCHD1,LRFN2,KCTD16,AMPH,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,KALRN,CAMK2A,CAMK2B,CREM,TMEM35A,ENO2,ERBB4,NRN1,FGF14,NBEA,GABRB3,DISC1,GRIA2,GRIN2C,LRRTM1,MAP2,MAPT,GIT1,NTRK2,OXTR,GPR85,TMOD2,NLGN3,PRKCB,RASGRF1,CARF,KCNIP3,RYR3,ARX,CPEB3,SLC6A8,CCDC88A,SP4,STX1A,ARC,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,RNF103,ST8SIA2" Mouse Phenotype MP:0009538 abnormal synapse morphology 2.80E-09 2.03E-05 8.48E-07 8.03E-06 65 206 "LRFN2,GAS7,MADD,CADPS,KIF1A,CACNA1A,CACNB4,KALRN,CAMK2A,CBLN1,DLGAP2,CACNA2D2,PLAA,CLCN3,TMEM184B,ARHGEF6,CLIP3,ERC2,RIMS2,DGKB,DCTN1,SNAP91,DMD,DNM1,DTNA,EDNRB,MBNL2,GPHN,ERBB2,NRN1,NBEA,GABRG2,PCDH17,GPT2,PCLO,GRIK4,LRRTM1,MAP6,MAPT,MBNL1,AFDN,NRCAM,NTRK2,ZDHHC8,NLGN3,SH3TC2,RET,PRRT2,STX1B,SCN8A,SH3GL3,NLGN1,SLC6A8,NAPB,CPEB4,MYCBP2,NFASC,CLSTN2,STX1A,SYNE2,SYN2,SYNE1,UCHL1,SLC30A3,SLC17A7" Mouse Phenotype MP:0001468 abnormal temporal memory 2.98E-09 2.17E-05 8.63E-07 8.17E-06 62 193 "ADCY8,ADD2,PTCHD1,LRFN2,KCTD16,AMPH,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,KALRN,CAMK2A,CAMK2B,CREM,NCOR1,TMEM35A,ENO2,ERBB4,NRN1,FGF14,NBEA,GABRB3,DISC1,GRIA2,GRIN2C,LRRTM1,MAP2,MAPT,GIT1,NTRK2,OXTR,PCDH9,GPR85,TMOD2,NLGN3,PRKCB,RASGRF1,CARF,KCNIP3,RYR3,ARX,CPEB3,SLC6A8,CCDC88A,TET1,SP4,STX1A,ARC,SYN2,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,RNF103,SLC17A7,ST8SIA2,JPH3" Mouse Phenotype MP:0003492 abnormal involuntary movement 3.09E-09 2.24E-05 8.63E-07 8.17E-06 211 954 "ACHE,ADCY8,ADRA1D,LRFN2,AP2A2,KIAA1324,ABCD2,PKP4,KCNAB2,PRX,MADD,SPTBN4,ARNTL,ASPA,ATP1A3,ATP2A2,ATP2B2,KIF1A,ADAM23,BBS2,RGS9,HCN2,BMP7,SYNJ1,MTMR2,CACNA1I,CACNA1G,WASF1,MYRF,CA8,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,CAST,CCK,USP2,CACNA2D2,CFL2,ASIC3,CHN1,PLAA,PPT2,CLCN3,TPP1,VAX2,QKI,CNGA3,WHRN,GAL3ST1,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,CSF1,ARHGEF4,CYBB,ARHGAP32,HDAC4,ZBTB24,SNAP91,DMD,DNM1,DMTF1,SLC12A6,DNM1L,EDIL3,EDNRA,EGR3,EMX2,ERBB2,ERCC2,NCALD,ADGRV1,FDFT1,PRMT5,FGF11,FGF14,FGFR1,SUCO,FOXO3,EVL,FLNC,NBEA,STAMBP,BRSK1,FYN,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,DISC1,SRRM4,CPLX2,GATM,PPARGC1A,NTNG2,GLI2,GNAO1,GRIA2,GRIK4,GRIK5,CACFD1,GRIN2D,ATE1,CIT,PSIP1,NXPH3,CPT1C,KCND2,KIF5A,L1CAM,LAMA2,MAPT,MBP,PPM1L,MITF,DBNL,MYO5A,MYO6,MYO7A,NF1,NFIX,NOVA1,NPR2,NRCAM,NTRK2,NTRK3,OPA1,CLDN11,OXTR,PAX6,TMOD2,ABCB1,NLGN3,TMIE,GPSM2,PRIMPOL,PMP22,MBOAT7,PRODH,RELN,LAMA1,PTPRG,PEX2,SH3TC2,RDX,FIGN,SETD5,RORB,EPHA10,KCNIP3,SATB1,ATXN7,SCN8A,SH3BP2,FBXO11,PREX2,WDR47,SLC12A2,SNAP25,SNCA,ANKFN1,SP4,SPP1,ZNF423,ERBIN,STX1A,JMJD6,PLCB1,TACR1,AGTPBP1,IQCE,TCF4,ZEB1,TRIM2,AP4E1,ZNF106,TK2,TLR4,CSMD1,WBP2,TRIO,TSC1,SSBP2,UBE3A,UCHL1,UGT8,VLDLR,WNT7A,KLC2,LGI4,ZIC1,ZIC2,ZNF24,NDRG4,DPYSL5,SLC30A4,RNF103,SLC17A7,PDSS2,EPM2A,FZD3,GJC2,AP3B2,JPH3" Mouse Phenotype MP:0002065 abnormal fear/anxiety-related behavior 9.38E-09 6.82E-05 2.52E-06 2.39E-05 103 393 "ADCY8,ADORA1,ADORA2A,ADRA1B,LRFN2,ALK,APBA2,ASPA,ATP1A1,ATP1A3,RGS9,WASF1,BAIAP3,CACNA1B,DDR1,CACNB4,KALRN,CAMK2A,CAMK2B,CHRNA4,NDST3,CNR1,AKAP5,ZNF521,CREM,CRHBP,CSF1R,SLITRK5,BRINP1,KIAA0319,LYPD1,SNAP91,NR1D2,SHANK1,TMEM35A,ENO2,ERBB4,FGF13,FGF14,FYN,GABBR1,CHL1,GABRG2,DISC1,CPLX2,PPARGC1A,GLUL,MCHR1,TPPP,GRIA2,GRM2,GRM8,FAM19A2,SYNPO,LRRTM1,L1CAM,LSAMP,MAP2,MAP6,MAPT,MOV10,GIT1,MYO7A,NPY,NTRK2,PDE4B,NLGN3,SERPINI1,JAKMIP1,HYDIN,PTCH1,PTPRG,ATAT1,KCNIP3,RYR3,SCN8A,ARX,CPEB3,SNAP25,KIF13A,SP4,SSTR2,STX1A,ARHGEF9,DNAJC9,ARC,TACR1,ADGRL3,ATMIN,TCF4,CRTC1,THRA,NR2E1,CSMD1,RASD2,NR2C2,TRPM2,TSC1,TOM1L2,ELFN1,RNF103,TUBA1A,SLC17A7" Mouse Phenotype MP:0002062 abnormal associative learning 9.99E-09 7.26E-05 2.59E-06 2.45E-05 87 315 "ASIC1,ADCY8,ADD2,PTCHD1,ADRA1B,LRFN2,KCTD16,DOC2A,AMPH,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,CACNA1B,KALRN,CAMK2A,CAMK2B,CHRNA4,TAOK2,CNR1,CREM,CYBB,DBN1,LYPD1,TMEM35A,ENO2,ERBB4,NRN1,PPP1R1B,FGF13,FGF14,NBEA,FYN,GABBR1,GABRB3,DISC1,GHR,MCHR1,GRIA2,GRIN2C,LRRTM1,MAP2,MAPT,GIT1,MYO5A,IDNK,NTRK2,OPRL1,OXTR,PDE4B,GPR85,TMOD2,NLGN3,JAKMIP1,PRKACB,PRKCB,MAPK3,PTPRG,RASGRF1,RGS4,CARF,KCNIP3,RYR3,ARX,CPEB3,SLC6A8,CCDC88A,ANKFN1,SP4,STX1A,ARC,TACR1,CRTC1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,RNF103,EPM2A,FZD3,ST8SIA2,JPH3" Mouse Phenotype MP:0000947 convulsive seizures 1.17E-08 8.52E-05 2.94E-06 2.78E-05 57 177 "SYN3,AMPH,ATP1A3,HCN2,NRP2,BID,SYNJ1,SGCE,C5,CACNA1A,CACNB4,CACNA2D2,CHN1,CHRNA4,CLCN3,TPP1,QKI,HDAC4,PLPPR4,SNAP91,DNM1,MBNL2,ADGRV1,FYN,GABBR1,B4GALNT1,PPARGC1A,DCLK2,TPPP,GRIA2,GRIK4,ATE1,CIT,HLF,MBP,DBNL,ADAM22,MYO5A,PMP22,FITM2,PRRT2,ATXN7,SCN8A,ARX,ST8SIA1,SNAP25,SST,PLCB1,SYN1,SYN2,SZT2,UBE3A,ZNF24,CELF4,EPM2A,GJC2,AP3B2" Mouse Phenotype MP:0000801 abnormal temporal lobe morphology 1.23E-08 8.95E-05 2.98E-06 2.82E-05 99 375 "FZD9,LRFN2,AGT,SEMA6A,APBB2,SPTBN4,CADPS,NUMB,TMEM108,ATP1A3,ATP2B2,BBS2,NRP2,BID,KALRN,PTBP2,CAMK2A,DCLK1,ARHGAP33,NUMBL,CHN2,LHX2,CLCN3,ZNF521,CRMP1,CSF1,CST3,PLXNA4,DGKB,BRINP1,DBN1,SHANK1,SLC12A6,PDCD6IP,EDIL3,EMX2,ENO2,APC2,FGF13,FGF14,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,DISC1,CPLX2,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HSF2,ZIC5,LRRTM1,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NF1,NFIX,PAX6,ABCB1,MBOAT7,PPP3CA,RELN,RGS4,LRRK2,ATAT1,ARX,CPEB3,SLC6A8,CCDC88A,CDK5RAP2,SNAP25,SNCA,SOX11,SP2,SP4,MYCBP2,ZNF423,PLCB1,SYN1,AGTPBP1,THRA,NR2E1,TRIO,TSC1,TSC2,VLDLR,SLC30A3,TUBA1A,EPM2A,UBE3B,ST8SIA2" Mouse Phenotype MP:0004811 abnormal neuron physiology 1.55E-08 1.12E-04 3.63E-06 3.43E-05 158 682 "NDRG2,UNC5A,SLC24A4,PCDH19,SORCS2,AMPH,APAF1,GAS7,SEMA4G,CASK,CADPS,NUMB,ATP1A3,ATP2B2,KIF1A,HCN2,NRP2,WASF1,CA8,CALB1,KALRN,HAP1,CAMK2A,CAST,ARHGEF2,CDH2,DLGAP2,NUMBL,CACNA2D2,COPB2,PLAA,PPT2,CNR1,WHRN,MAGED1,CREM,CRMP1,NCOR2,AATK,CSNK1E,CNTNAP2,RIMS2,SNPH,HDAC4,KIF26A,MAML1,DAPK1,SNAP91,DNM1,CDON,DNM1L,EDIL3,CELSR3,PLXNC1,EMX2,ENO2,APC2,ADGRV1,FKTN,PRMT5,FGF13,FGFR1,MAD2L2,VTI1B,GABBR1,GABRG2,GAD1,CPLX2,CPLX1,GLI2,KDM2B,GPR37,GRIA2,GRM2,CIT,GSTM5,IGF1,INSM1,KCNJ16,KCNQ3,KIF2A,KIF5A,LAMA2,LIG4,MAPT,MBP,MEF2C,DBNL,BLOC1S2,MYCN,MYO7A,NCAM2,NEFH,NF1,NOVA1,NTRK2,OGG1,PAX6,PDPK1,PLCB2,PLXNB1,MBOAT7,KANSL1,MAPK9,MAPK10,RELN,PTCH1,STRC,OXR1,RET,RFX3,RIC8B,ROBO1,FBXW7,STX1B,SCN8A,TNFRSF19,SH3GL3,ARX,CPEB3,SLC6A8,CCDC88A,NAPB,TET1,SMARCC2,CDK5RAP2,SNCA,SOX11,SP2,SPP1,ZNF423,STX1A,SYN1,SYT1,TACR1,TAL1,TCF4,CUX2,THRA,TLR4,NR2E1,TP53BP2,IL34,NR2C2,TRIO,TSC1,FLRT2,VLDLR,XRCC4,TRIM9,DPYSL5,MAP3K12,GDPD5,TUBA1A,PDSS2,EPM2A,ST8SIA2,GAN" Mouse Phenotype MP:0003861 abnormal nervous system development 2.10E-08 1.52E-04 4.76E-06 4.51E-05 263 1269 "ABR,SYN3,ADD1,AXIN2,BRAP,FZD9,PCDH19,NME5,CC2D2A,BBOX1,AMT,SEMA7A,EP400,APAF1,APBB2,APC,EPB41L5,PRX,CHRD,NUMB,DYNLL1,ATP2B2,BARD1,NRP2,BMP7,BMPR1B,WASF1,CACNA1A,KALRN,HAP1,PTBP2,ISPD,KRIT1,CDH2,DCLK1,NOG,NUMBL,CACNA2D2,CHN1,CHN2,NDST3,SLIT2,LHX2,NGEF,VAX2,QKI,HECTD1,CNN3,CNR1,CNTN1,COX4I1,RTTN,ZNF521,NCOR1,NCOR2,CSF1,CSF1R,PLXNA4,PYGO1,BOC,ARHGAP32,HDAC4,KIF26A,KIAA0586,BRINP1,DCTN1,FBXL5,KIF19,MED12,CDON,SHANK1,DPH1,PDCD6IP,DTNA,DTNB,DNM1L,E2F5,EBF1,EDIL3,WDPCP,EDN3,CELSR3,APH1A,EGFR,EMX2,COQ7,EPHB1,GPHN,ERBB2,ERBB4,ETV1,NRN1,TUBB3,DLC1,ZMYND10,FDFT1,PRMT5,SEC24B,FGFR1,VTI1B,EVL,TMEM107,SMC2,AK8,ATP2C1,DLL3,FUT9,BRSK1,GALC,IP6K3,SRRM4,GDF1,GLI2,KDM2B,GPT2,GRIA2,RNF165,SYNPO,ZDHHC15,DHX35,ZIC5,RBPJ,LRRCC1,IL6ST,INSM1,ITGA7,KIF2A,KIT,L1CAM,LAMA2,LIG4,LMO2,SMAD1,SMAD9,MAP2,MAPT,MBD1,MEIS2,KITLG,MITF,AFDN,MSI1,BLOC1S2,MYCN,MYO9A,NEFH,NEK1,NF1,NFIX,NRCAM,NTRK2,OPA1,PAX6,PCSK5,PDE4B,ENPP2,PDPK1,NLGN3,PIK3C2A,PKD1,PLXNB1,PSAT1,MBOAT7,PRKACB,CEP41,MAPK7,MAPK9,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,TMEM231,RAD17,CCDC40,RAD51D,FAT4,KHDRBS2,CRTAC1,RET,REV3L,FIGN,RGS4,KIF7,ROBO1,ROBO2,FBXW7,LRRK2,RXRA,SALL1,SCN8A,KIF27,ARX,FUZ,AMBRA1,NLGN1,DZIP1,EPN2,DHX30,CCDC88A,TET1,CPEB4,SMARCA4,SMARCC2,CDK5RAP2,IFT122,SOX11,SP2,NMNAT2,MYCBP2,UNC5B,ZNF423,SPTAN1,MESP1,SS18,STAU1,TTBK2,JMJD6,SYN1,SYN2,COBL,MLST8,ATMIN,TCF4,CUX2,ZEB1,RPGRIP1L,TCF12,USP22,TEK,DICER1,SIRT1,GPR161,THRA,TIAM1,HEY1,TLR4,NR2E1,PARD3,TP53BP2,CDK20,TRIO,TSC1,TSC2,HIRA,TOM1L2,VLDLR,ZBTB14,ZIC1,ZIC2,TRIM9,CRB2,SPHK2,MAP3K12,GDPD5,PRDM8,ADAMTS9,PDSS2,FZD3,RTN4,IFT88,ST8SIA2" Mouse Phenotype MP:0004166 abnormal limbic system morphology 2.88E-08 2.09E-04 6.32E-06 5.98E-05 106 416 "FZD9,LRFN2,AGT,SEMA6A,ALK,APAF1,APBB2,CADPS,NUMB,TMEM108,ATP1A3,BBS2,NRP2,BID,WASF1,KALRN,HAP1,PTBP2,CAMK2A,DCLK1,NUMBL,CHN2,LHX2,CLCN3,ZNF521,CLOCK,CRMP1,CSF1,CST3,PLXNA4,DGKB,BRINP1,DBN1,SHANK1,SLC12A6,PDCD6IP,EDIL3,EMX2,ENO2,APC2,FGF13,FGF14,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,DISC1,CPLX2,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HSF2,ZIC5,LRRTM1,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NF1,NFIX,NTRK2,PAX6,ABCB1,MBOAT7,PPP3CA,RELN,RGS4,LRRK2,ATAT1,ARX,CPEB3,SLC6A8,CCDC88A,TET1,CDK5RAP2,SNAP25,SNCA,SOX3,SOX11,SP2,SP4,MYCBP2,ZNF423,PLCB1,SYN1,AGTPBP1,DMXL2,THRA,NR2E1,TRIO,TSC1,TSC2,VLDLR,ZIC2,SLC30A3,TUBA1A,EPM2A,UBE3B,ST8SIA2" Mouse Phenotype MP:0004859 abnormal synaptic plasticity 3.00E-08 2.18E-04 6.32E-06 5.98E-05 30 70 "ADD2,LRFN2,NRP2,KSR1,CAMK2A,CAMK2B,CLCN3,CNR1,PICK1,AKAP5,DBN1,SNAP91,MBNL2,CPLX2,CPLX1,GRIA2,MAP6,NTRK2,NLGN3,RASGRF1,PRRT2,STX1A,ARHGEF9,SYP,RIMBP2,UCHL1,VLDLR,CLIP2,ELFN1,ANKS1B" Mouse Phenotype MP:0002067 abnormal sensory capabilities/reflexes/nociception 3.05E-08 2.21E-04 6.32E-06 5.98E-05 207 957 "ACHE,ADCY8,ADORA1,ADORA2A,ADRA1D,LRFN2,AP2A2,KIAA1324,PKP4,PRX,MADD,SPTBN4,ARNTL,ARRB2,ASPA,ATP1A3,ATP2A2,ATP2B2,KIF1A,BBS2,RGS9,HCN2,MTMR2,CACNA1I,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,CAST,CCK,USP2,P2RX6,CACNA2D2,CFL2,ASIC3,CHN1,CHRNA4,PLAA,PPT2,TPP1,CNGA3,HOMER3,CNR1,WHRN,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,CNTNAP2,ARHGEF4,CYBB,ARHGAP32,HDAC4,GIT2,ZBTB24,SNAP91,DMTF1,SLC12A6,DNM1L,EDIL3,EDNRA,EDNRB,KMT5B,EMX2,ENO2,GPHN,ERBB2,ERCC2,NCALD,ADGRV1,FGF11,FGF14,FGFR1,SUCO,FOXO3,EVL,FLNC,FLT1,NBEA,STAMBP,BRSK1,FYN,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,DISC1,SRRM4,CPLX2,GATM,PPARGC1A,NTNG2,GLI2,GNAO1,GRIA2,GRIK4,GRIK5,CACFD1,GRIN2D,ATE1,PSIP1,MAP4K5,NXPH3,CPT1C,KCND2,L1CAM,LAMA2,MAPT,MBP,PPM1L,MITF,DBNL,MYO5A,MYO6,MYO7A,NBL1,NF1,NFIX,NPR2,NRCAM,NTRK2,NTRK3,OPA1,OPRL1,OXTR,P2RX7,PAX6,PCDH9,TMOD2,NLGN3,TMIE,RETREG1,GPSM2,PLCB2,PMP22,MBOAT7,PRKAR1B,PRODH,RELN,LAMA1,PTPRG,PEX2,SH3TC2,RDX,FIGN,RGS4,SETD5,ROBO2,RORB,EPHA10,KCNIP3,S100B,SATB1,ATXN7,SCN8A,SH3BP2,ARX,FBXO11,PREX2,WDR47,SLC12A2,SNAP25,SNCA,SP4,MYCBP2,SPP1,ERBIN,STX1A,JMJD6,PLCB1,TACR1,TCF4,ZEB1,PHF24,AP4E1,ZNF106,TLR4,NR2E1,CSMD1,WBP2,NR2C2,TRIO,TSC1,SSBP2,UBE3A,UCHL1,WNT7A,KLC2,LGI4,ZIC1,ZIC2,KCNT2,NDRG4,DPYSL5,SLC30A4,RNF103,SLC17A7,PDSS2,EPM2A,FZD3,RNF170,JPH3" Mouse Phenotype MP:0001463 abnormal spatial learning 4.92E-08 3.57E-04 9.93E-06 9.40E-05 71 248 "ASIC1,ADD2,FZD9,ADRA1B,LRFN2,AMPH,KCNAB2,CHRD,NCOA1,ATP1A3,WASF1,CACNA1B,CAMK2A,DLGAP2,ARHGEF6,AKAP5,CLOCK,CRMP1,CYBB,SHANK1,EDIL3,ENO2,NRN1,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,FYN,DISC1,CPLX2,GRIA2,NXPH3,SYNPO,CPT1C,L1CAM,MAPT,MBD1,MBP,ADAM11,GIT1,NF1,NRCAM,NTRK2,OPRL1,PDE1B,TMOD2,NLGN3,FA2H,RASGRF1,KCNIP3,RYR3,ARX,SLC6A8,CCDC88A,TET1,SNAP25,SP4,CLSTN2,ARHGEF9,PLCB1,ARC,TCF4,NR2E1,TSC1,TSC2,UBE3A,VGF,ZIC2,NDRG4,KCNAB1" Mouse Phenotype MP:0009745 abnormal behavioral response to xenobiotic 7.14E-08 5.19E-04 1.40E-05 1.33E-04 82 303 "ADCY5,FZD9,ADORA2A,ADRA1D,ADRA1B,SORCS2,UNC79,ALK,AMPH,ATP1A1,ATP1A3,MPDZ,HCN2,NRP2,CACNA1G,BAIAP3,CACNA1A,CACNA1B,CACNA2D1,CACNB4,P2RX6,CACNA2D2,CHRNA4,TAOK2,CLCN3,CNR1,AKAP5,CLOCK,SLITRK5,GPRASP1,ARHGAP32,DGKB,NR1D2,SLC12A6,EDIL3,MBNL2,ENO2,PPP1R1B,FGF14,PDLIM5,FYN,GABRB3,GABRG2,DISC1,PPARGC1A,MCHR1,GRIK4,GRIK5,GRM2,CIT,GSTM5,HLF,KIT,LAMP2,MAP6,MAPT,MBP,NPY,NTRK2,OPRL1,SLC10A4,PLCL1,SH3KBP1,MAPK10,PTPRO,PRRT2,RGS4,LRRK2,KCNIP1,SCN2B,SCN8A,ARX,SLC4A3,SLC6A11,FAIM2,PLCB1,TACR1,ADGRL3,SZT2,TRPM2,ELFN1,ANKS1B" Mouse Phenotype MP:0000807 abnormal hippocampus morphology 9.13E-08 6.63E-04 1.75E-05 1.65E-04 95 369 "FZD9,LRFN2,AGT,SEMA6A,APBB2,CADPS,NUMB,TMEM108,ATP1A3,BBS2,NRP2,BID,KALRN,PTBP2,CAMK2A,DCLK1,NUMBL,CHN2,LHX2,CLCN3,ZNF521,CRMP1,CSF1,CST3,PLXNA4,DGKB,BRINP1,DBN1,SHANK1,SLC12A6,PDCD6IP,EDIL3,EMX2,ENO2,APC2,FGF13,FGF14,AK8,STAMBP,BRSK1,FYN,CHL1,GABRB3,CPLX2,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HSF2,ZIC5,LRRTM1,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NF1,NFIX,PAX6,ABCB1,MBOAT7,PPP3CA,RELN,RGS4,LRRK2,ATAT1,ARX,CPEB3,SLC6A8,CCDC88A,CDK5RAP2,SNAP25,SNCA,SOX11,SP2,SP4,MYCBP2,ZNF423,PLCB1,SYN1,AGTPBP1,THRA,NR2E1,TRIO,TSC1,TSC2,VLDLR,SLC30A3,TUBA1A,EPM2A,UBE3B,ST8SIA2" Mouse Phenotype MP:0003312 abnormal locomotor coordination 1.11E-07 8.05E-04 2.04E-05 1.93E-04 155 685 "ABR,ACHE,PTCHD1,ABCD2,AMPD2,AMPD3,APBA2,PRX,SPTBN4,ARNTL,ASPA,NUMB,ATP1A3,ATP2B2,KIF1A,ADAM23,HCN2,BID,PROM1,SYNJ1,MTMR2,MYRF,CA8,CACNA1A,CACNA1B,CACNB4,CALB1,CAMK2B,CAST,CBLN1,RGN,CACNA2D2,CHN1,PLAA,PPT2,CLCN3,TPP1,QKI,CNTN1,WHRN,GAL3ST1,CSF1R,DAPK1,DCTN1,DMD,DNM1,SLC12A6,E2F5,E2F6,EDIL3,EGR3,ERBB2,ERCC2,APC2,ETV1,FDFT1,FGF12,FGF14,FGFR1,FGFR3,SUCO,GAA,GABBR1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,CPLX2,CPLX1,HPGDS,GLI2,GRM8,CIT,HAS2,ZIC5,ITGA7,KCNB1,L1CAM,LAMA2,LIG4,LSAMP,MAPT,MBP,MEF2C,PPM1L,AFF1,GIT1,DBNL,MSI1,ADAM22,MYO5A,MYO6,MYO7A,MYO9A,NF1,NFIX,NRCAM,NTRK3,OPA1,TMIE,PMP22,MBOAT7,HYDIN,RELN,LAMA1,PTCH1,PEX2,OXR1,FIGN,ROBO2,RORB,GLDN,STX1B,ATXN7,SCN8A,ARX,PREX2,SLC6A8,SLC12A2,NAPB,SNAP25,SNCA,ANKFN1,ZNF423,NFASC,STXBP1,VPS13A,CAMTA1,AGTPBP1,TRIM2,USP22,ZNF106,THRA,NACC2,TK2,TP53BP2,TRIO,TSC1,TSC2,UBE3A,UCHL1,UGT8,VLDLR,WNT7A,ZIC1,NDRG4,REEP1,PDSS2,EPM2A,GJC2,RNF170,FXR1,GAN" Mouse Phenotype MP:0002910 abnormal excitatory postsynaptic currents 1.12E-07 8.16E-04 2.04E-05 1.93E-04 47 143 "SYN3,ADORA1,LRFN2,APBA2,MADD,CADPS,TMEM108,RGS9,CACNA1A,KALRN,CAMK2A,CBLN1,CLCN3,LYPD1,PLPPR4,SNAP91,DNM1,SEZ6L2,FGF13,NBEA,CSPG5,GABBR1,GABRB3,CPLX2,CPLX1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,LRRTM1,IGSF11,NLGN3,STX1B,SH3GL3,NLGN1,CCDC88A,NAPB,STX1A,PLCB1,SYT1,RIMBP2,ELFN1,ANKS1B,SLC17A7,NETO2,NETO1" Mouse Phenotype MP:0001961 abnormal reflex 1.19E-07 8.67E-04 2.11E-05 2.00E-04 173 784 "ACHE,ADCY8,ADRA1D,LRFN2,AP2A2,KIAA1324,PKP4,PRX,MADD,SPTBN4,ARNTL,ASPA,ATP1A3,ATP2A2,ATP2B2,KIF1A,BBS2,RGS9,MTMR2,CACNA1I,CACNA1A,CACNA1B,CACNB4,CALB1,KALRN,CAST,CCK,USP2,CACNA2D2,CFL2,ASIC3,CHN1,PLAA,PPT2,CNGA3,WHRN,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,ARHGEF4,CYBB,ARHGAP32,HDAC4,ZBTB24,SNAP91,DMTF1,SLC12A6,DNM1L,EDIL3,EDNRA,EMX2,ERBB2,ERCC2,NCALD,ADGRV1,FGF11,FGF14,FGFR1,SUCO,FOXO3,EVL,FLNC,NBEA,STAMBP,BRSK1,FYN,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,DISC1,SRRM4,CPLX2,GATM,PPARGC1A,NTNG2,GLI2,GNAO1,GRIA2,GRIK4,GRIK5,CACFD1,GRIN2D,ATE1,PSIP1,NXPH3,CPT1C,KCND2,L1CAM,LAMA2,MAPT,MBP,PPM1L,MITF,DBNL,MYO5A,MYO6,MYO7A,NF1,NFIX,NPR2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,PAX6,TMOD2,NLGN3,TMIE,GPSM2,PMP22,MBOAT7,PRODH,RELN,LAMA1,PTPRG,PEX2,SH3TC2,RDX,FIGN,SETD5,RORB,EPHA10,KCNIP3,SATB1,ATXN7,SCN8A,SH3BP2,FBXO11,PREX2,WDR47,SLC12A2,SNAP25,SNCA,SP4,SPP1,ERBIN,STX1A,JMJD6,PLCB1,TACR1,TCF4,ZEB1,AP4E1,ZNF106,TLR4,CSMD1,WBP2,TRIO,TSC1,SSBP2,UBE3A,UCHL1,WNT7A,KLC2,LGI4,ZIC1,ZIC2,NDRG4,DPYSL5,SLC30A4,RNF103,SLC17A7,PDSS2,EPM2A,FZD3,JPH3" Mouse Phenotype MP:0009358 environmentally induced seizures 5.10E-07 3.71E-03 8.83E-05 8.36E-04 22 48 "SYN3,ADORA1,ATP1A3,NRP2,CACNA1A,TPP1,CNTNAP2,HDAC4,ADGRV1,FGF13,FYN,GABBR1,B4GALNT1,HLF,MBP,PRRT2,ST8SIA1,SYN1,SYN2,TSC2,UBE3A,ELFN1" Mouse Phenotype MP:0009937 abnormal neuron differentiation 5.37E-07 3.90E-03 9.07E-05 8.59E-04 92 367 "ABR,SYN3,SEMA7A,APAF1,APBB2,NUMB,ATP2B2,NRP2,BMPR1B,HAP1,PTBP2,ISPD,CDH2,DCLK1,NUMBL,CHN1,CHN2,SLIT2,NGEF,VAX2,CNR1,CNTN1,ZNF521,NCOR1,NCOR2,PLXNA4,ARHGAP32,KIF26A,BRINP1,EDIL3,CELSR3,EMX2,EPHB1,GPHN,ETV1,NRN1,TUBB3,FGFR1,VTI1B,EVL,BRSK1,SRRM4,GLI2,GRIA2,RNF165,RBPJ,INSM1,KIF2A,L1CAM,MAPT,MBD1,AFDN,BLOC1S2,MYCN,NEFH,NTRK2,PAX6,PDE4B,ENPP2,PLXNB1,MBOAT7,RELN,LAMA1,PTCH1,CRTAC1,RET,KIF7,ROBO1,ROBO2,FBXW7,LRRK2,CCDC88A,TET1,CPEB4,SMARCC2,SOX11,SP2,NMNAT2,MYCBP2,USP22,TLR4,NR2E1,TP53BP2,TRIO,TSC1,TRIM9,MAP3K12,GDPD5,PRDM8,PDSS2,RTN4,ST8SIA2" Mouse Phenotype MP:0002557 abnormal social/conspecific interaction 6.11E-07 4.44E-03 1.01E-04 9.55E-04 92 368 "SYN3,ADORA2A,LRFN2,APBA2,APC,DDO,SPTBN4,NUMB,CACNA1A,CACNA1B,KALRN,CAMK2A,CAMK2B,DLGAP2,DLGAP1,NUMBL,CACNA2D2,CNR1,WHRN,MAGED1,ZNF521,CSF1,CSF1R,CNTNAP2,RIMS2,ARHGAP32,BRINP1,SNAP91,SHANK1,EDN3,NBEA,CSPG5,DLL3,FYN,GABRB3,DISC1,CPLX1,GNAL,GNAO1,MCHR1,GRIA2,GSTM5,HNF4G,HNMT,NKD1,LRRTM1,L1CAM,LAMA2,LSAMP,MAP6,MAPT,MBP,MEST,MITF,MYO7A,NRCAM,NTRK2,OXTR,PCDH9,ABCB1,NLGN3,TMIE,JAKMIP1,PMP22,MAGEL2,RELN,FIGN,RGS4,RORB,SAFB,ARX,NLGN1,SLC12A2,MBD5,SP4,STX1A,VPS13A,SYN1,SYN2,ZEB1,CRTC1,SIRT1,CHST8,THRA,NR2E1,TRPM2,TSC1,TSC2,UBE3A,LGI4,ZIC2,TUBA1A" Mouse Phenotype MP:0001362 abnormal anxiety-related response 6.32E-07 4.59E-03 1.02E-04 9.66E-04 89 353 "ADCY8,ADORA1,ADORA2A,ALK,APBA2,ASPA,ATP1A1,ATP1A3,RGS9,WASF1,BAIAP3,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CHRNA4,NDST3,CNR1,AKAP5,ZNF521,CREM,CRHBP,CSF1R,SLITRK5,BRINP1,KIAA0319,LYPD1,SNAP91,NR1D2,SHANK1,TMEM35A,ENO2,ERBB4,FGF13,FGF14,CHL1,GABRG2,DISC1,CPLX2,PPARGC1A,MCHR1,TPPP,GRIA2,GRM2,GRM8,FAM19A2,SYNPO,LRRTM1,L1CAM,LSAMP,MAP6,MAPT,MOV10,GIT1,MYO7A,NPY,NTRK2,PDE4B,NLGN3,SERPINI1,JAKMIP1,ATAT1,KCNIP3,SCN8A,ARX,CPEB3,SNAP25,KIF13A,SSTR2,STX1A,ARHGEF9,DNAJC9,TACR1,ADGRL3,ATMIN,TCF4,CRTC1,THRA,NR2E1,CSMD1,RASD2,NR2C2,TRPM2,TSC1,ELFN1,RNF103,TUBA1A,SLC17A7" Mouse Phenotype MP:0012317 impaired conditioning behavior 7.03E-07 5.11E-03 1.11E-04 1.05E-03 42 129 "PTCHD1,ADRA1B,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,CACNA1B,CAMK2A,CAMK2B,CHRNA4,TAOK2,CNR1,DBN1,TMEM35A,ENO2,ERBB4,NRN1,PPP1R1B,FGF13,FGF14,GRIA2,GRIN2C,MAPT,GIT1,IDNK,PDE4B,NLGN3,RASGRF1,RGS4,CARF,ARX,SLC6A8,CCDC88A,ANKFN1,SP4,STX1A,TACR1,CRTC1,UBE3A,ZIC2,FZD3" Mouse Phenotype MP:0001393 ataxia 9.76E-07 7.09E-03 1.51E-04 1.43E-03 85 336 "ABCD2,APBA2,SPTBN4,ASPA,NUMB,ATP1A3,ATP2B2,KIF1A,ADAM23,HCN2,BID,PROM1,SYNJ1,MYRF,CA8,CACNA1A,CACNB4,CALB1,CAMK2B,CBLN1,CACNA2D2,PLAA,PPT2,TPP1,QKI,CNTN1,GAL3ST1,CSF1R,DNM1,SLC12A6,E2F5,E2F6,EGR3,ERBB2,ERCC2,ETV1,FDFT1,FGF12,FGF14,GALC,B4GALNT1,CPLX1,HPGDS,CIT,LAMA2,LIG4,MAPT,MBP,AFF1,MSI1,ADAM22,MYO5A,NF1,NFIX,NRCAM,OPA1,PMP22,HYDIN,RELN,PTCH1,OXR1,GLDN,STX1B,ATXN7,SCN8A,SLC12A2,NAPB,SNAP25,ZNF423,NFASC,STXBP1,CAMTA1,AGTPBP1,TRIM2,THRA,TRIO,TSC1,TSC2,UCHL1,UGT8,VLDLR,ZIC1,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0002945 abnormal inhibitory postsynaptic currents 2.38E-06 1.73E-02 3.55E-04 3.37E-03 31 87 "SYN3,SEMA6A,APBA2,BAIAP3,CACNA1A,CACNA1B,CHRNA4,CNR1,ERC2,SNAP91,DNM1,FGF13,NBEA,CSPG5,GABBR1,GABRG2,GAD1,CPLX2,CPLX1,DCLK2,GPR37,NOVA2,NLGN3,PRRT2,STX1B,NLGN1,STX1A,ARHGEF9,SYN1,SYT1,SYT5" Mouse Phenotype MP:0002915 abnormal synaptic depression 2.40E-06 1.74E-02 3.55E-04 3.37E-03 41 130 "SYN3,ADCY8,ADORA1,ADGRB3,RGS9,SYNJ1,WASF1,CAMK2A,CAMK2B,CBLN1,ARHGEF6,CNR1,PICK1,AKAP5,SV2B,CSPG5,DISC1,PCDH17,PCLO,GRIA2,GRM2,LAMA2,MAPT,MYO5A,PDE4B,NLGN3,PRKACB,PRKAR1B,RYR3,SH3GL3,CPEB3,STX1A,ARHGEF9,SYN1,SYN2,SYT1,UCHL1,VGF,ELFN1,DPYSL5,ANKS1B" Mouse Phenotype MP:0009956 abnormal cerebellar layer morphology 2.86E-06 2.08E-02 4.16E-04 3.94E-03 82 329 "ABR,SORCS2,SPARCL1,SEMA6A,ABCD2,SEMA4G,CADPS,NCOA1,NUMB,ATP2B2,BID,SGCE,CACNA1G,CA8,CACNA1A,CALB1,CBLN1,CACNA2D2,SLIT2,PLAA,PPT2,TPP1,QKI,CNTN1,AKAP12,DNM1,DNM1L,EDIL3,EGFR,ENO2,ERBB4,ERCC2,APC2,FGF13,AP4B1,B4GALNT1,IP6K3,GLI2,GRIN2C,CIT,IGF1,L1CAM,MAP2,AFF1,MYCN,MYO5A,NRCAM,NTRK2,PAX6,PLXNB1,FA2H,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,ROBO2,FBXW7,ATXN2,ATXN7,SCN8A,PREX2,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,TRIO,TSC1,TSC2,UGT8,VLDLR,XRCC4,DPYSL5,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0001900 impaired synaptic plasticity 3.05E-06 2.22E-02 4.35E-04 4.12E-03 20 45 "ADD2,KSR1,CAMK2A,CLCN3,PICK1,DBN1,MBNL2,CPLX2,CPLX1,GRIA2,MAP6,NTRK2,NLGN3,RASGRF1,STX1A,SYP,VLDLR,CLIP2,ELFN1,ANKS1B" Mouse Phenotype MP:0001454 abnormal cued conditioning behavior 4.09E-06 2.97E-02 5.72E-04 5.41E-03 40 128 "ADD2,PTCHD1,KCTD16,AMPH,KSR1,CAMK2A,CNR1,CREM,CYBB,DBN1,LYPD1,TMEM35A,ENO2,ERBB4,NRN1,FGF13,FGF14,LRRTM1,MAPT,GIT1,IDNK,PDE4B,TMOD2,NLGN3,JAKMIP1,PRKACB,PRKCB,PTPRG,ARX,ANKFN1,SP4,STX1A,ARC,CRTC1,TSC1,VLDLR,ZIC2,SPIRE1,FZD3,ST8SIA2" Mouse Phenotype MP:0000788 abnormal cerebral cortex morphology 4.31E-06 3.13E-02 5.91E-04 5.60E-03 92 384 "SORCS2,APAF1,APBB2,NUMB,ATP2B2,BBS2,FUBP1,WASF1,KALRN,HAP1,PTBP2,CDH2,DCLK1,ARHGAP33,NUMBL,COPB2,CHN1,LHX2,PPT2,CLCN3,CNR1,CRMP1,NCOR2,PLXNA4,BRINP1,CDON,DPYSL2,PDCD6IP,E2F5,CELSR3,EGFR,EMX2,EPHB1,APC2,ZMYND10,PRMT5,FGF1,FGF13,SMC2,STAMBP,BRSK1,FYN,CHL1,GAD1,DISC1,SRRM4,PPARGC1A,GPT2,ZIC5,LRRTM1,KIF2A,L1CAM,LIG4,MAP2,MAPT,AFDN,MSI1,BLOC1S2,MYCN,NF1,NFIX,NTRK2,PAX6,PCDH9,PLXNB1,MBOAT7,HYDIN,RELN,PEX2,PRRT2,RGS4,FBXW7,ARX,CCDC88A,SMARCC2,CDK5RAP2,SNAP25,SOX11,MYCBP2,CUX2,USP22,TP53BP2,TSC1,TSC2,UBE3A,VLDLR,XRCC4,ZIC2,MAP3K12,TUBA1A,FZD3,ST8SIA2" Mouse Phenotype MP:0003008 enhanced long term potentiation 4.65E-06 3.38E-02 6.23E-04 5.89E-03 25 65 "LRFN2,CHRD,WASF1,CAMK2A,CNR1,AKAP5,ERBB4,BAIAP2,NBEA,GRIA2,ITPKA,LAMA2,NELL2,OPRL1,PDE4B,TMOD2,PTN,KCNIP3,RYR3,ARHGEF9,ARC,TCF4,ICAM5,TSC2,KCNAB1" Mouse Phenotype MP:0001473 reduced long term potentiation 4.71E-06 3.42E-02 6.23E-04 5.89E-03 46 156 "ADCY8,ADD2,DOC2A,RGS9,KSR1,CACNA1B,CALB2,KALRN,CAMK2A,CAMK2B,ARHGEF6,AKAP5,CYBB,DGKB,MBNL2,TMEM35A,PPP1R1B,FGF14,FYN,GABBR1,DISC1,CPLX2,GRIK4,SYNPO,LRRTM1,MAPT,NTRK2,IGSF11,PPP1R1A,PRKACB,PRKAR1B,MAPK3,MAPK9,RASGRF1,CCDC88A,SP4,STX1A,ARC,SYP,TSC1,UBE3A,VLDLR,ELFN1,SLC17A7,NETO1,JPH3" Mouse Phenotype MP:0000950 abnormal seizure response to pharmacological agent 5.04E-06 3.66E-02 6.43E-04 6.09E-03 42 138 "FZD9,AMPH,ATP1A3,HCN2,NRP2,CACNA1G,BAIAP3,CACNA1A,P2RX6,CACNA2D2,CHRNA4,CLCN3,CNR1,AKAP5,ARHGAP32,SLC12A6,EDIL3,MBNL2,FGF14,GABRB3,GABRG2,GRIK4,GRIK5,CIT,MAPT,MBP,NPY,SLC10A4,PLCL1,MAPK10,PTPRO,PRRT2,KCNIP1,SCN2B,SCN8A,ARX,SLC4A3,SLC6A11,FAIM2,PLCB1,SZT2,ELFN1" Mouse Phenotype MP:0000849 abnormal cerebellum morphology 5.05E-06 3.67E-02 6.43E-04 6.09E-03 108 470 "ABR,SORCS2,SPARCL1,SEMA6A,ABCD2,SEMA4G,SPTBN4,CADPS,NCOA1,NUMB,ATP2B2,BID,FUBP1,SGCE,CACNA1G,CA8,CACNA1A,CALB1,CBLN1,ARHGEF2,DCLK1,CACNA2D2,SLIT2,PLAA,PPT2,TPP1,QKI,CNTN1,ZNF521,AKAP12,DNM1,SLC12A6,DNM1L,E2F6,EDIL3,EGFR,ENO2,EPB41L2,ERBB4,ERCC2,APC2,PRMT5,FGF13,FGFR1,AP4B1,MEGF10,GABRB3,GALC,B4GALNT1,IP6K3,DISC1,PPARGC1A,GLI2,GRIN2C,CIT,IGF1,KIF2A,L1CAM,MAP2,MBP,AFF1,MYCN,MYO5A,NRCAM,NTRK2,OPA1,PAX6,JAKMIP1,PLXNB1,FA2H,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,FIGN,ROBO2,FBXW7,ATXN2,ATXN7,SCN8A,PREX2,SOX11,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,RPGRIP1L,THRA,ENHO,TRIO,TSC1,TSC2,UBE3A,UGT8,VLDLR,XRCC4,ZIC1,DPYSL5,PDSS2,EPM2A,GJC2,ST8SIA2" Mouse Phenotype MP:0003107 abnormal response to novelty 7.67E-06 5.57E-02 9.61E-04 9.10E-03 75 301 "ADORA2A,ADRA1B,APBA2,CHRD,ATP1A1,ATP1A3,STX16,BCL7A,WASF1,BAIAP3,CHRNA4,CLCN3,QKI,ARHGEF6,CNR1,MAGED1,CLOCK,NCOR1,CNTNAP2,ERC2,ARHGAP32,DGKB,BRINP1,SNAP91,SLC12A6,ENO2,ERCC2,FGF12,FGF14,GABBR1,CHL1,GABRB3,DISC1,CPLX2,GNAL,GRIA2,GRM8,LRRTM1,L1CAM,LSAMP,NPY,NTRK2,OPA1,OPRL1,PDE4B,PDE1B,ZDHHC8,SERPINI1,SH3KBP1,PKIA,RORB,ARX,SLC6A8,CCDC88A,MBD5,SP4,SSTR2,STX1A,ARHGEF9,TAF6,WSCD1,TCF4,DMXL2,CRTC1,SLC44A1,NR2E1,TSC1,TSC2,ELFN1,ZNF142,GDPD5,TUBA1A,AAAS,ST8SIA2,JPH3" Mouse Phenotype MP:0004097 abnormal cerebellar cortex morphology 9.49E-06 6.89E-02 1.17E-03 1.11E-02 88 370 "ABR,SORCS2,SPARCL1,SEMA6A,ABCD2,SEMA4G,CADPS,NCOA1,NUMB,ATP2B2,BID,FUBP1,SGCE,CACNA1G,CA8,CACNA1A,CALB1,CBLN1,DCLK1,CACNA2D2,SLIT2,PLAA,PPT2,TPP1,QKI,CNTN1,AKAP12,DNM1,DNM1L,EDIL3,EGFR,ENO2,ERBB4,ERCC2,APC2,FGF13,FGFR1,AP4B1,GABRB3,B4GALNT1,IP6K3,GLI2,GRIN2C,CIT,IGF1,L1CAM,MAP2,AFF1,MYCN,MYO5A,NRCAM,NTRK2,PAX6,PLXNB1,FA2H,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,FIGN,ROBO2,FBXW7,ATXN2,ATXN7,SCN8A,PREX2,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,TRIO,TSC1,TSC2,UGT8,VLDLR,XRCC4,ZIC1,DPYSL5,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0012349 increased susceptibility to induction of seizure by inducing agent 1.61E-05 1.17E-01 1.93E-03 1.83E-02 35 112 "FZD9,AMPH,ATP1A3,HCN2,NRP2,BAIAP3,CACNA1A,CACNA2D2,CHRNA4,CNR1,ARHGAP32,SLC12A6,EDIL3,MBNL2,FGF14,GABRB3,GABRG2,GRIK4,GRIK5,CIT,MBP,NPY,SLC10A4,PLCL1,PTPRO,PRRT2,KCNIP1,SCN2B,ARX,SLC4A3,FAIM2,PLCB1,SZT2,ELFN1,CELF4" Mouse Phenotype MP:0005404 abnormal axon morphology 1.62E-05 1.18E-01 1.93E-03 1.83E-02 58 221 "ABCD2,PRX,SPTBN4,CADPS,CACNA1A,CD86,SEPT7,DCLK1,CACNA2D2,QKI,TMEM184B,GAL3ST1,AATK,VCAN,SNPH,SLC12A6,DRP2,EPHB1,ERBB2,FGF13,CAMKK2,GABBR1,CHL1,GALC,ZIC5,KIF2A,MAPT,MBP,PPM1L,NEFH,NFE2L2,NRCAM,NTRK2,CLDN11,NLGN3,PLEC,PMP22,FA2H,PRPH,PTPN13,SH3TC2,KHDRBS2,GLDN,LRRK2,NLGN1,SNCA,SPTAN1,NFASC,ERBIN,SEPT8,MTCL1,TRIM2,ZNF106,TLR4,LGI4,ZNF24,SLC17A7,GAN" Domain IPR011993 PH_dom-like InterPro 7.70E-15 5.24E-11 5.24E-11 4.93E-10 116 427 "ABR,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,APBA2,APBB2,EPB41L5,SPTBN4,CADPS,NUMB,KIF1A,DOCK11,ARHGEF7,BTK,MTMR3,MTMR2,KALRN,ARHGEF25,MTMR7,ARHGEF1,LRBA,ARHGEF2,NUMBL,PLEKHB1,ARHGAP22,NGEF,HOMER3,ARHGEF6,CDC42BPB,SH2B1,ARHGEF10,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,ELMO1,TIAM2,DNM1,RASA4,PLEKHA1,EPB41,EPB41L2,PTK2B,AGAP2,AGAP3,RGPD5,EVL,PSD2,NBEA,FERMT2,ADAP1,GRB10,PLCD4,CIT,FRMD5,FRMD3,JAK2,SHC3,MYO7A,PDPK1,PLCB2,PLCD1,PLCL1,EPB41L4B,RANBP3L,PSD,MTMR10,PTK2,PTPN13,PID1,IQSEC3,RASGRF1,RASGRF2,RDX,RGS3,RGS12,SBF1,RASA3,SH3BP2,FRMPD1,FERMT1,ASAP3,SHC4,CNKSR2,PREX2,PPP4R3A,ARHGEF40,ELMO2,DOK5,ARHGAP26,IQSEC2,MCF2L2,MPRIP,PHLDB1,ARHGEF9,PLCB1,MCF2L,DOCK9,TNS2,ARHGAP9,TIAM1,TNS1,WBP2,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,ANKS1B,FRMD6,SPATA13" Domain IPR013164 Cadherin_N InterPro 5.61E-14 3.82E-10 1.27E-10 1.20E-09 34 65 "PCDH19,PCDH10,PCDHGB4,PCDH17,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Domain PF08266 Cadherin_2 Pfam 5.61E-14 3.82E-10 1.27E-10 1.20E-09 34 65 "PCDH19,PCDH10,PCDHGB4,PCDH17,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Domain 2.30.29.30 - Gene3D 1.31E-13 8.92E-10 2.23E-10 2.10E-09 106 391 "ABR,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,APBA2,APBB2,EPB41L5,SPTBN4,CADPS,NUMB,KIF1A,DOCK11,ARHGEF7,BTK,MTMR3,MTMR2,KALRN,ARHGEF25,MTMR7,ARHGEF1,ARHGEF2,NUMBL,PLEKHB1,ARHGAP22,NGEF,HOMER3,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,ELMO1,TIAM2,DNM1,RASA4,PLEKHA1,EPB41,EPB41L2,AGAP2,AGAP3,EVL,PSD2,FERMT2,ADAP1,GRB10,PLCD4,CIT,FRMD5,FRMD3,SHC3,MYO7A,PDPK1,PLCD1,PLCL1,EPB41L4B,RANBP3L,PSD,MTMR10,PTPN13,PID1,IQSEC3,RASGRF1,RASGRF2,RDX,RGS3,RGS12,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,SHC4,CNKSR2,PREX2,PPP4R3A,ARHGEF40,ELMO2,DOK5,ARHGAP26,IQSEC2,MCF2L2,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,TNS2,ARHGAP9,TIAM1,TNS1,WBP2,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,ANKS1B,FRMD6,SPATA13" Domain IPR002126 Cadherin InterPro 3.58E-11 2.44E-07 4.88E-08 4.58E-07 44 118 "PCDH19,PCDH10,PCDHGB4,CDH2,KIAA0319,CELSR3,FREM1,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain PF00028 Cadherin Pfam 1.12E-10 7.61E-07 1.27E-07 1.19E-06 42 113 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain PS50268 CADHERIN_2 PROSITE 1.55E-10 1.05E-06 1.32E-07 1.24E-06 42 114 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain 2.60.40.60 - Gene3D 1.55E-10 1.05E-06 1.32E-07 1.24E-06 42 114 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain PF16492 Cadherin_C_2 Pfam 1.99E-10 1.35E-06 1.32E-07 1.24E-06 23 42 "PCDH10,PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7" Domain IPR032455 Cadherin_C InterPro 1.99E-10 1.35E-06 1.32E-07 1.24E-06 23 42 "PCDH10,PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7" Domain SM00112 CA SMART 2.13E-10 1.45E-06 1.32E-07 1.24E-06 42 115 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain IPR015919 Cadherin-like InterPro 2.91E-10 1.98E-06 1.65E-07 1.55E-06 42 116 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,RET,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain IPR001849 PH_domain InterPro 4.28E-10 2.91E-06 2.13E-07 2.01E-06 76 281 "ABR,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,ELMO1,TIAM2,DNM1,RASA4,PLEKHA1,AGAP2,AGAP3,PSD2,FERMT2,ADAP1,GRB10,PLCD4,CIT,PDPK1,PLCD1,PLCL1,PSD,IQSEC3,RASGRF1,RASGRF2,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,TEX2,ARHGAP26,IQSEC2,MCF2L2,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,SPATA13" Domain PS00232 CADHERIN_1 PROSITE 4.39E-10 2.99E-06 2.13E-07 2.01E-06 41 113 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain IPR020894 Cadherin_CS InterPro 4.82E-10 3.28E-06 2.19E-07 2.06E-06 40 109 "PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,PCDH17,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,DCHS2,FAT4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20" Domain SM00233 PH SMART 7.52E-10 5.12E-06 3.20E-07 3.01E-06 75 279 "ABR,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,ELMO1,TIAM2,DNM1,RASA4,PLEKHA1,AGAP2,AGAP3,PSD2,FERMT2,ADAP1,GRB10,PLCD4,CIT,PLCD1,PLCL1,PSD,IQSEC3,RASGRF1,RASGRF2,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,TEX2,ARHGAP26,IQSEC2,MCF2L2,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,SPATA13" Domain PS50003 PH_DOMAIN PROSITE 8.96E-10 6.10E-06 3.59E-07 3.38E-06 75 280 "ABR,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,ELMO1,TIAM2,DNM1,RASA4,PLEKHA1,AGAP2,AGAP3,PSD2,FERMT2,ADAP1,GRB10,PLCD4,CIT,PDPK1,PLCD1,PLCL1,PSD,IQSEC3,RASGRF1,RASGRF2,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,ARHGAP26,IQSEC2,MCF2L2,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,SPATA13" Domain PF15974 Cadherin_tail Pfam 4.14E-09 2.82E-05 1.49E-06 1.40E-05 20 37 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Domain IPR031904 Cadherin_CBD InterPro 4.14E-09 2.82E-05 1.49E-06 1.40E-05 20 37 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Domain PF00169 PH Pfam 7.68E-09 5.23E-05 2.62E-06 2.46E-05 63 230 "ABR,PLEKHH1,OSBPL6,OSBPL8,CDC42BPA,FGD2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,TIAM2,DNM1,RASA4,PLEKHA1,AGAP2,AGAP3,PSD2,FERMT2,ADAP1,GRB10,PLCD4,CIT,PLCD1,PSD,RASGRF1,RASGRF2,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,CNKSR2,PREX2,DOK5,ARHGAP26,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,SPATA13" Domain SM00060 FN3 SMART 2.27E-08 1.55E-04 7.36E-06 6.92E-05 53 185 "ELFN2,LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,BOC,KIAA0319,CDON,FSD1L,EBI3,EPHB1,SPEG,FLNC,CHL1,GHR,PTPRT,IL6R,IL6ST,L1CAM,LIFR,MID1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,ROBO1,ROBO2,EPHA10,FNDC3A,TRIM67,ANKFN1,NFASC,ASTN2,OBSL1,TEK,RIMBP2,FLRT2,TRIM9" Domain PF00041 fn3 Pfam 3.25E-08 2.21E-04 1.01E-05 9.45E-05 48 162 "LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,BOC,CDON,FSD1L,EBI3,EPHB1,SPEG,CHL1,GHR,PTPRT,IL6R,IL6ST,L1CAM,LIFR,MID1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,ROBO1,ROBO2,EPHA10,FNDC3A,TRIM67,ANKFN1,NFASC,OBSL1,TEK,RIMBP2,FLRT2,TRIM9" Domain PF07679 I-set Pfam 6.03E-08 4.10E-04 1.71E-05 1.61E-04 53 190 "UNC5A,LRFN2,ADGRF5,LRFN1,IGDCC4,MYOM1,KALRN,IGLON5,CNTN1,NRG2,IGDCC3,LRIG1,BOC,MFAP3L,CDON,SPEG,FGFR1,FGFR3,FLT1,CHL1,SIGLEC8,IGSF5,ADGRA3,LINGO1,VSIG4,IGFBPL1,NEGR1,L1CAM,LSAMP,NCAM2,NRCAM,NTRK2,NTRK3,IGSF11,CNTN3,PRTG,SDK2,LRRN3,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,UNC5B,NFASC,OBSL1,ICAM5,LRRC24,TRIO,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain IPR013098 Ig_I-set InterPro 6.03E-08 4.10E-04 1.71E-05 1.61E-04 53 190 "UNC5A,LRFN2,ADGRF5,LRFN1,IGDCC4,MYOM1,KALRN,IGLON5,CNTN1,NRG2,IGDCC3,LRIG1,BOC,MFAP3L,CDON,SPEG,FGFR1,FGFR3,FLT1,CHL1,SIGLEC8,IGSF5,ADGRA3,LINGO1,VSIG4,IGFBPL1,NEGR1,L1CAM,LSAMP,NCAM2,NRCAM,NTRK2,NTRK3,IGSF11,CNTN3,PRTG,SDK2,LRRN3,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,UNC5B,NFASC,OBSL1,ICAM5,LRRC24,TRIO,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain IPR000719 Prot_kinase_dom InterPro 2.35E-07 1.60E-03 6.39E-05 6.01E-04 105 489 "CLK4,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DCLK2,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,MAP3K12,WNK3,WNK2" Domain IPR003961 FN3_dom InterPro 2.85E-07 1.94E-03 7.46E-05 7.02E-04 55 209 "ELFN2,LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,BOC,KIAA0319,CDON,FSD1L,EBI3,EPHB1,SPEG,FLNC,CHL1,GHR,PTPRT,IL6R,IL6ST,L1CAM,LIFR,MID1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,ROBO1,ROBO2,EPHA10,LRFN5,FNDC3A,TRIM67,ATF7IP,ANKFN1,NFASC,ASTN2,OBSL1,TEK,RIMBP2,FLRT2,TRIM9" Domain PS50853 FN3 PROSITE 3.09E-07 2.10E-03 7.79E-05 7.32E-04 53 199 "ELFN2,LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,BOC,CDON,FSD1L,EBI3,EPHB1,SPEG,CHL1,GHR,PTPRT,IL6R,IL6ST,L1CAM,LIFR,MID1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,ROBO1,ROBO2,EPHA10,LRFN5,FNDC3A,TRIM67,ATF7IP,ANKFN1,NFASC,ASTN2,OBSL1,TEK,RIMBP2,FLRT2,TRIM9" Domain PS50011 PROTEIN_KINASE_DOM PROSITE 3.56E-07 2.42E-03 8.64E-05 8.13E-04 105 493 "CLK4,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DCLK2,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,MAP3K12,WNK3,WNK2" Domain IPR011009 Kinase-like_dom InterPro 4.43E-07 3.02E-03 1.04E-04 9.78E-04 113 543 "CLK4,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,DST,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMD,DNM1,DMPK,RPS6KL1,PDCD6IP,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DCLK2,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,KNDC1,JAK2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PIK3C2A,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,SNRK,PTK2,STK32A,PTPN13,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,CHD9,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,MAP3K12,WNK3,WNK2" Domain SM00408 IGc2 SMART 6.05E-07 4.12E-03 1.33E-04 1.25E-03 59 235 "LRFN2,ADGRF5,ALCAM,LRFN1,IGDCC4,MYOM1,KALRN,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,CSF1R,LRIG1,BOC,MFAP3L,CDON,SPEG,FCGR1A,FCGR1B,FGFR1,FGFR3,SEMA4D,FLT1,CHL1,SIGLEC8,MALT1,LILRA2,LINGO1,VSIG4,IGFBPL1,NEGR1,IL6R,KIT,L1CAM,LSAMP,NCAM2,NRCAM,NTRK2,IGSF11,CNTN3,PRTG,SDK2,LRRN3,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,UNC5B,NFASC,OBSL1,ICAM5,LRRC24,TRIO,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain IPR003598 Ig_sub2 InterPro 6.05E-07 4.12E-03 1.33E-04 1.25E-03 59 235 "LRFN2,ADGRF5,ALCAM,LRFN1,IGDCC4,MYOM1,KALRN,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,CSF1R,LRIG1,BOC,MFAP3L,CDON,SPEG,FCGR1A,FCGR1B,FGFR1,FGFR3,SEMA4D,FLT1,CHL1,SIGLEC8,MALT1,LILRA2,LINGO1,VSIG4,IGFBPL1,NEGR1,IL6R,KIT,L1CAM,LSAMP,NCAM2,NRCAM,NTRK2,IGSF11,CNTN3,PRTG,SDK2,LRRN3,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,UNC5B,NFASC,OBSL1,ICAM5,LRRC24,TRIO,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain PS00107 PROTEIN_KINASE_ATP PROSITE 7.71E-07 5.25E-03 1.64E-04 1.54E-03 98 459 "CLK4,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,HIPK3,EGFR,IRAK4,TNK2,SRPK3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DCLK2,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK2,KIT,MARK1,MARK3,MATK,NEK1,NTRK2,NTRK3,CDK18,PDPK1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,MAP3K12,WNK3,WNK2" Domain PS50106 PDZ PROSITE 1.49E-06 1.01E-02 3.04E-04 2.86E-03 42 151 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4,GORASP1" Domain PF00595 PDZ Pfam 1.52E-06 1.03E-02 3.04E-04 2.86E-03 40 141 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4" Domain IPR001478 PDZ InterPro 1.79E-06 1.22E-02 3.49E-04 3.28E-03 42 152 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4,GORASP1" Domain IPR001452 SH3_domain InterPro 1.92E-06 1.31E-02 3.64E-04 3.42E-03 55 221 "CASKIN1,AMPH,BIN1,GAS7,CASK,ZNF582,DST,ARHGEF7,BTK,CACNB4,KALRN,ARHGAP33,NGEF,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SHANK1,DOCK2,TNK2,SH3YL1,PRAM1,BAIAP2,MPP6,FYB1,FYN,PACSIN2,MATK,MIA2,MPP2,DBNL,MYO7A,NCF2,PIK3R1,SH3KBP1,SH3TC2,SH3GL3,SLA,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,SH3GLB2,SPATA13" Domain PS00741 DH_1 PROSITE 2.54E-06 1.73E-02 4.68E-04 4.40E-03 23 63 "ABR,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain 2.30.42.10 - Gene3D 3.20E-06 2.18E-02 5.73E-04 5.38E-03 41 150 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4,GORASP1" Domain IPR017441 Protein_kinase_ATP_BS InterPro 3.52E-06 2.40E-02 6.15E-04 5.78E-03 82 379 "CLK4,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CDK13,STK33,MARK4,BMPR1B,BTK,KALRN,CAMK2A,CAMK2B,CAMK2G,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,HIPK3,EGFR,TNK2,SRPK3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,PTK2B,TAOK3,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,TTBK1,DCLK2,CIT,MAP4K5,MYLK2,NIM1K,JAK2,KIT,MARK1,MARK3,MATK,NEK1,NTRK2,NTRK3,CDK18,PDPK1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,SNRK,PTK2,STK32A,RET,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,CDK19,NEK4,TTBK2,SIK3,TEK,CDK20,SGK3" Domain IPR018159 Spectrin/alpha-actinin InterPro 3.90E-06 2.65E-02 6.47E-04 6.09E-03 15 32 "ACTN1,SPTBN4,DST,KALRN,AKAP6,DMD,DRP2,PLEC,SPTAN1,SPTB,MCF2L2,SYNE2,MCF2L,SYNE1,TRIO" Domain SM00150 SPEC SMART 3.90E-06 2.65E-02 6.47E-04 6.09E-03 15 32 "ACTN1,SPTBN4,DST,KALRN,AKAP6,DMD,DRP2,PLEC,SPTAN1,SPTB,MCF2L2,SYNE2,MCF2L,SYNE1,TRIO" Domain PS50002 SH3 PROSITE 5.30E-06 3.61E-02 8.56E-04 8.05E-03 53 217 "CASKIN1,AMPH,BIN1,GAS7,CASK,DST,ARHGEF7,BTK,CACNB4,KALRN,ARHGAP33,NGEF,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SHANK1,DOCK2,TNK2,SH3YL1,PRAM1,BAIAP2,MPP6,FYB1,FYN,PACSIN2,MATK,MPP2,DBNL,MYO7A,NCF2,PIK3R1,SH3KBP1,SH3TC2,SH3GL3,SLA,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,SH3GLB2,SPATA13" Domain PS50010 DH_2 PROSITE 5.54E-06 3.77E-02 8.56E-04 8.05E-03 24 70 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain PF00621 RhoGEF Pfam 5.54E-06 3.77E-02 8.56E-04 8.05E-03 24 70 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain SM00228 PDZ SMART 5.66E-06 3.85E-02 8.56E-04 8.05E-03 40 148 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4" Domain IPR019748 FERM_central InterPro 6.75E-06 4.60E-02 9.78E-04 9.19E-03 19 49 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain IPR000299 FERM_domain InterPro 6.75E-06 4.60E-02 9.78E-04 9.19E-03 19 49 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain IPR000219 DH-domain InterPro 7.33E-06 4.99E-02 1.02E-03 9.58E-03 24 71 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain 1.20.900.10 - Gene3D 7.33E-06 4.99E-02 1.02E-03 9.58E-03 24 71 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain PF00435 Spectrin Pfam 9.16E-06 6.23E-02 1.16E-03 1.09E-02 12 23 "ACTN1,SPTBN4,DST,KALRN,DMD,DRP2,SPTAN1,SPTB,SYNE2,MCF2L,SYNE1,TRIO" Domain IPR019749 Band_41_domain InterPro 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain PS00661 FERM_2 PROSITE 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain SM00295 B41 SMART 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain IPR014352 FERM/acyl-CoA-bd_prot_3-hlx InterPro 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,DBI,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain PS00660 FERM_1 PROSITE 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain PS50057 FERM_3 PROSITE 9.54E-06 6.50E-02 1.16E-03 1.09E-02 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain PF00373 FERM_M Pfam 1.01E-05 6.89E-02 1.21E-03 1.14E-02 18 46 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Domain SM00325 RhoGEF SMART 1.12E-05 7.60E-02 1.31E-03 1.23E-02 23 68 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Domain SM00326 SH3 SMART 1.15E-05 7.85E-02 1.33E-03 1.25E-02 52 217 "CASKIN1,AMPH,BIN1,GAS7,CASK,ARHGEF7,BTK,CACNB4,KALRN,ARHGAP33,NGEF,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SHANK1,DOCK2,TNK2,SH3YL1,PRAM1,BAIAP2,MPP6,FYB1,FYN,PACSIN2,MATK,MPP2,DBNL,MYO7A,NCF2,PIK3R1,SH3KBP1,SH3TC2,SH3GL3,SLA,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,SH3GLB2,SPATA13" Domain PF07653 SH3_2 Pfam 1.24E-05 8.42E-02 1.38E-03 1.30E-02 27 87 "CASKIN1,AMPH,BIN1,CASK,ARHGEF7,ARHGAP33,ARHGEF6,DOCK4,RUSC2,SHANK1,DOCK2,BAIAP2,MPP6,FYB1,MIA2,MPP2,PIK3R1,SH3KBP1,SH3TC2,SH3GL3,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,RIMBP2,SH3GLB2" Domain IPR011511 SH3_2 InterPro 1.24E-05 8.42E-02 1.38E-03 1.30E-02 27 87 "CASKIN1,AMPH,BIN1,CASK,ARHGEF7,ARHGAP33,ARHGEF6,DOCK4,RUSC2,SHANK1,DOCK2,BAIAP2,MPP6,FYB1,MIA2,MPP2,PIK3R1,SH3KBP1,SH3TC2,SH3GL3,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,RIMBP2,SH3GLB2" Domain IPR001331 GDS_CDC24_CS InterPro 1.55E-05 1.05E-01 1.70E-03 1.60E-02 16 39 "ABR,ARHGEF7,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,PREX2,MCF2L,DNMBP,TIAM1,TRIO,VAV1" Pathway 1268763 Neuronal System BioSystems: REACTOME 8.25E-14 2.36E-10 2.36E-10 2.01E-09 96 351 "KCNH8,SYN3,ACHE,ADCY5,ADCY6,ADCY8,LRFN2,AP2A1,AP2A2,BEGAIN,LRFN1,PPFIA4,APBA2,KCNAB2,EPB41L5,PPFIA3,CASK,BCHE,HCN2,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2A,CAMK2B,CAMK2G,KCNAB3,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,NRXN3,HOMER3,PICK1,AKAP5,SIPA1L1,SHANK1,EPB41,EPB41L2,NCALD,PDLIM5,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,CPLX1,GLUL,KCNMB4,GNAL,GNG4,GRIA2,GRIK4,GRIK5,CACFD1,GRIN2C,GRIN2D,LRRTM1,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNN1,KCNN2,KCNN3,KCNQ3,DBNL,MYO6,PDPK1,GNG2,NLGN3,PLCB2,PRKACB,PRKCB,PTPRD,RASGRF1,RASGRF2,RPS6KA2,NLGN1,SLC6A11,SNAP25,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SLC38A1,SLC17A7,KCNAB1" Pathway 169346 Regulation of RAC1 activity BioSystems: Pathway Interaction Database 1.06E-10 3.03E-07 1.52E-07 1.29E-06 22 39 "ABR,ARHGDIA,ARHGEF7,KALRN,ARHGEF25,ARHGEF2,CHN1,CHN2,NGEF,ARHGEF6,ELMO1,TIAM2,DOCK2,RAP1GDS1,RASGRF1,RASGRF2,PREX2,ARHGAP9,TIAM1,TRIO,VAV1,SPATA13" Pathway 1268766 Transmission across Chemical Synapses BioSystems: REACTOME 1.14E-09 3.25E-06 1.08E-06 9.25E-06 61 218 "SYN3,ACHE,ADCY5,ADCY6,ADCY8,AP2A1,AP2A2,PPFIA4,PPFIA3,CASK,BCHE,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2A,CAMK2B,CAMK2G,CACNA2D2,CHRNA4,PICK1,AKAP5,NCALD,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,CPLX1,GLUL,GNAL,GNG4,GRIA2,GRIK4,GRIK5,CACFD1,GRIN2C,GRIN2D,KCNJ5,KCNJ16,MYO6,PDPK1,GNG2,PLCB2,PRKACB,PRKCB,RASGRF1,RASGRF2,RPS6KA2,SLC6A11,SNAP25,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SLC38A1,SLC17A7" Pathway P00057 Wnt signaling pathway PantherDB 2.20E-07 6.28E-04 1.57E-04 1.34E-03 71 305 "AXIN2,FZD9,PCDH19,PCDH10,EP400,MYH7B,APC,ARRB1,ARRB2,PCDHGB4,BMPR1B,CDH2,SMARCAL1,CSNK1E,CSNK1G3,PYGO1,EDN1,CELSR3,APC2,SRCAP,GNG4,NKD1,CDH20,SMAD1,MYCN,MYH3,PCDHGC3,PCDH8,PCDH9,GNG2,PLCB2,PCDH18,PPP2R5E,PPP3CA,PPP3CC,PRKCB,ANKRD6,SMARCA4,SMARCC2,SMARCD3,PLCB1,FBXW11,TBL1X,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,WNT7A,PCDH20,FZD3" Pathway 1270303 Axon guidance BioSystems: REACTOME 2.79E-07 7.98E-04 1.57E-04 1.34E-03 112 554 "BRAP,UNC5A,AP2A1,AP2A2,SEMA6A,ALCAM,ANK2,SEMA7A,SPTBN4,ARRB1,ARRB2,NUMB,NRP2,KSR1,ARHGEF7,CACNA1I,CACNA1G,CACNB4,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,SLIT2,CLTB,CLTC,NGEF,CNTN1,COL4A5,COL9A1,COL9A3,NRG2,CRMP1,CSF2RA,PLXNA4,DNM1,DPYSL2,DUSP9,RASGRP1,APH1A,EGFR,PLXNC1,RASA4,EPHB1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,AGAP2,EVL,SEMA4D,WDR83,ABLIM2,FYN,CHL1,GFRA2,GRB10,GRIN2C,GRIN2D,JAK2,KCNQ3,KIT,L1CAM,MARK3,SHC3,KITLG,GIT1,NF1,NRCAM,KSR2,TREM2,PIK3R1,PLXNB1,PPP2R5E,PPP5C,PRKACB,MAPK3,MAPK7,PSMA6,LAMA1,PTK2,RASGRF1,RASGRF2,RDX,RET,ROBO1,ROBO2,EPHA10,RPS6KA2,SEMA6D,SCN2B,SCN7A,SCN8A,RASA3,CNKSR2,ABLIM3,DOK5,UNC5B,SPTAN1,SPTB,NFASC,CLASP2,CLASP1,TEK,TIAM1,DOK6,RGMB,TRIO,UBC,DPYSL5,ST8SIA2" Pathway P00012 Cadherin signaling pathway PantherDB 3.28E-07 9.39E-04 1.57E-04 1.34E-03 44 159 "FZD9,PCDH19,PCDH10,PCDHGB4,CDH2,CELSR3,EGFR,ERBB2,ERBB4,FER,FYN,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,WNT7A,PCDH20,FZD3" Pathway 1269443 Signalling by NGF BioSystems: REACTOME 7.25E-07 2.08E-03 2.96E-04 2.53E-03 99 483 "ABR,ADCY5,ADCY6,ADCY8,BRAP,ADORA2A,AP2A1,AP2A2,FGD2,TNRC6C,SPTBN4,ARHGDIA,ARRB1,ARRB2,KSR1,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,CD86,ARHGEF1,ARHGEF2,CLTC,NGEF,ARHGEF6,MAGED1,NRG2,CSF2RA,ARHGEF10,ARHGEF4,TIAM2,DNM1,DUSP9,RASGRP1,APH1A,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,FYN,GFRA2,TNRC6A,GRIN2C,GRIN2D,LINGO1,JAK2,KIT,PIK3AP1,MARK3,SHC3,MEF2C,KITLG,MOV10,NF1,NTRK2,KSR2,PCSK5,PDE1C,PDE1B,PDPK1,PIK3R1,MAPKAP1,PPP2R5E,PPP5C,PRKACB,PRKAR1B,MAPK3,MAPK7,PSMA6,PTK2,RASGRF1,RASGRF2,RET,RPS6KA2,MAPK12,RASA3,CNKSR2,ARHGEF40,SPTAN1,SPTB,ARHGEF9,MLST8,MCF2L,TEK,ITGB3BP,TIAM1,TRIO,TSC2,UBC,VAV1,RICTOR,RTN4" Pathway 1427850 Interactions of neurexins and neuroligins at synapses BioSystems: REACTOME 1.45E-06 4.16E-03 5.20E-04 4.44E-03 22 59 "BEGAIN,APBA2,EPB41L5,CASK,DLGAP2,DLGAP1,NRXN3,HOMER3,SIPA1L1,SHANK1,EPB41,EPB41L2,PDLIM5,GRIN2C,GRIN2D,LRRTM1,DBNL,NLGN3,NLGN1,STX1A,STXBP1,SYT1" Pathway 1427849 Protein-protein interactions at synapses BioSystems: REACTOME 1.80E-06 5.14E-03 5.71E-04 4.87E-03 25 73 "LRFN2,BEGAIN,LRFN1,APBA2,EPB41L5,CASK,DLGAP2,DLGAP1,NRXN3,HOMER3,SIPA1L1,SHANK1,EPB41,EPB41L2,PDLIM5,GRIN2C,GRIN2D,LRRTM1,DBNL,NLGN3,PTPRD,NLGN1,STX1A,STXBP1,SYT1" Pathway 83050 Calcium signaling pathway BioSystems: KEGG 6.91E-06 1.98E-02 1.98E-03 1.69E-02 45 182 "ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CALM1,CAMK2A,CAMK2B,CAMK2G,P2RX6,CD38,EDNRA,EDNRB,EGFR,ERBB2,ERBB4,PTK2B,GNAL,PLCD4,GRIN2C,GRIN2D,MYLK2,ITPKA,ITPKB,OXTR,P2RX7,PDE1C,PDE1B,PLCB2,PLCD1,PPP3CA,PPP3CC,PRKACB,PRKCB,RYR3,SLC8A1,PLCB1,TACR1,SPHK2" Pubmed 28671696 Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Pubmed 1.80E-88 3.12E-83 3.12E-83 3.95E-82 258 916 "ABR,ASIC1,TMEM132B,ADD1,AP2A1,AP2A2,CASKIN1,KCTD16,UNC79,BEGAIN,AMPD2,BIN1,LRFN1,OGT,LRCH2,PKP4,KCNAB2,APC,PPFIA3,CASK,SPTBN4,ZSCAN18,CCAR2,DYNLL1,SLC4A4,DOCK11,ADGRB2,ADGRB3,MPDZ,HCN2,SYNJ1,ARHGEF7,WASF1,CACNA1A,CACNA2D1,CACNB4,KALRN,CAMK2A,CAMK2B,CAMK2G,LDB2,DGKI,ARHGEF2,SEPT7,CDH2,DCLK1,LRRFIP1,MAGI1,DLGAP2,DLGAP1,NUMBL,TAOK2,EPS15L1,CLTC,NGEF,MAP4K4,HOMER3,CNTN1,ARMC8,SLC4A8,MAGED1,CNRIP1,CDC42BPB,PREPL,AKAP12,CRMP1,NCOR1,NCOR2,GDA,RGS6,SEC24C,OSBPL3,SIPA1L1,PDE4DIP,DZIP3,ERC2,APPL1,PPP6R2,GPRASP1,ARHGAP32,TCAF1,ARHGAP24,HDAC4,TBC1D5,MATR3,DAPK1,DAPK3,GIT2,DBN1,ARMCX4,DCTN1,JAKMIP2,MYEF2,KIAA0319,PLPPR4,SNAP91,SEC16A,EXOG,DNM1,SHANK1,DPYSL2,PDCD6IP,FARSB,DNM1L,FRY,EIF4G1,EPB41L2,MTSS1L,GPHN,APC2,RACK1,BAIAP2,AGAP2,RGPD5,ANKFY1,NOP56,SYT3,NBEA,SMC2,FAM49B,BRSK1,NEURL4,IQGAP2,GLUL,GNAO1,PRRC2B,TPPP,GRIA2,DIDO1,GRIK5,GRIN2D,GRM2,CIT,GSN,SYNPO,TJAP1,TMEM240,LRRTM1,KCNB1,KCNJ16,KIF2A,KIF5A,MAP6,AFDN,MPP2,GIT1,ADAM22,TAGLN3,MYO5A,HNRNPM,NEFH,CCDC13,NF1,NRCAM,NTRK2,KSR2,OPA1,P2RX7,PCDH8,PDE4A,PDE4B,PDE1B,NLGN3,PLCL1,JAKMIP1,STRN3,SH3KBP1,PPP3CA,PRKACB,PRKAR1B,PRKCB,MAPK3,PTK2,PTPRN2,IQSEC3,RDX,KIF7,PBRM1,RPS6KA2,CLIP1,RTN1,SBF1,ATXN2,CASC3,TRA2B,KIF21A,CNKSR2,SEC31A,ABLIM3,FAM81A,WDR47,CCDC88A,TRIM67,ATF7IP,SMARCA4,SMARCC2,CDK5RAP2,LIMCH1,TRERF1,HECW1,UHRF1BP1L,MYCBP2,ERC1,SPTAN1,IQSEC2,DDN,NFASC,CLASP2,ERBIN,MPRIP,SEPT3,KLHL7,ZC3H4,PRRC2C,SYNE2,DNAJC9,PLCB1,SYN1,ARC,SYT1,ANKRD28,MTCL1,TBL1X,SMG6,SIN3B,DMXL2,ZEB1,CLASP1,SYNE1,NSD1,SIK3,ICAM5,RIMBP2,PARD3,CABIN1,TNS1,TP53BP1,TP53BP2,LRRC24,TRIO,TSC1,TSC2,TTC3,HIRA,UBE3A,VGF,CLIP2,ZIC2,ANKS1B,EMSY,STOX2,PPP1R3F,KCNAB1,WNK3,WNK2,FXR1,NETO1,SPATA13" Pubmed 28611215 Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Pubmed 1.80E-69 3.14E-64 1.57E-64 1.98E-63 307 1489 "RALGAPA1,KCNH8,ABR,PLEKHH1,ESYT2,LRFN2,MTA3,ZNF608,INTS2,TBC1D14,SEMA6A,ALCAM,TRMT9B,PITPNM2,OGT,CDC42BPA,APBB2,TNRC6C,SHROOM2,CDC14B,SFMBT2,PPP4R4,CASK,SPTBN4,ARRB1,ARRB2,CDK13,NUMB,EIF4G3,SLC2A11,KIF1A,BARD1,BMPR1B,SYNJ2,FUBP1,BAIAP3,DDR1,PTBP2,CAMK2B,CAST,CBFA2T2,SCARB1,LRBA,ZMYM4,EVI5L,MAGI1,NUMBL,CACNA2D2,SRSF11,FOXN3,EPS15L1,RPL32P3,RAB28,NGEF,FAM19A5,HECTD1,FAM149A,COL4A5,MYRIP,ZNF385A,CDC42BPB,C2CD2,RBM39,SH2B1,ANKRD44,NCOR2,ABCG1,RASGEF1C,PHF14,GREB1,ARHGEF4,DCAF8,HDAC4,TM9SF4,TBC1D5,ZC3H11A,SGSM2,USP3,RPS6KL1,SLC12A6,DPP6,DPYSL2,PDCD6IP,DTNA,DTNB,TOM1,SNX29,HIPK3,FAM13A,SUGP2,EGFR,MBNL2,TNK2,PAN3,HSD17B14,VPS13B,EPB41,ERBB2,ETV1,ANKMY1,KATNAL1,ADGRV1,NSRP1,ZNF461,SH3YL1,ZNF589,FECH,FGF13,BAIAP2,PRKAG2,POLK,SCARA3,UBE2E3,AGAP3,FOXO3,EVL,SEMA4D,FOLH1,POMT1,ATP2C1,MPP6,ABLIM2,ZMAT1,ZNF44,TMEM8B,SEPT9,SESN1,AHDC1,MALT1,SPIN1,GLI2,GLYR1,TOX3,ZNF638,LUZP2,DCLK2,RAB40B,GNG4,GPT2,PRUNE2,FUT10,GRB10,PARD3B,RNF165,BVES,GUCY1A1,MAN1B1,FRMD3,SYNPO,IGF1,KNDC1,TJAP1,IL6R,ITPKB,JAK2,KLHL23,KCNN2,LSS,PACRG,MAP2,MAP4,MAPT,MARK3,MBNL1,MBP,MKLN1,AFF1,MMP16,MYO5A,MYO6,MYO9A,MYT1,NCAM2,NFIX,KSR2,NUCB2,OPRL1,GPR137C,ZNF827,PDE4D,PFKFB4,NLGN3,PSAT1,EPB41L4B,POLG,PPARA,TATDN3,PPP2R2C,PPP3CA,VSTM2L,PRKACB,PRKAR1B,NDUFS7,BCAS3,VPS13C,WDR25,PTK2,PTPN13,PTPRB,PTPRE,PTPRG,PTPRN2,C1orf109,RIPOR1,MARCH1,ZNF793,HKR1,ZDHHC14,SLC25A36,RIC8B,ZNF532,SETD5,KIAA0895L,SGSM1,RPS6KA2,ATAT1,KCNIP3,RXRA,ZNF331,ATXN2,ATXN7,SCP2,FNIP1,TNFRSF19,CASC3,GALNT10,RASA3,SCAF8,SH3BGR,SH3BP2,FRMPD1,CHD9,WDR37,NBPF1,KANSL3,PKNOX2,MAST1,RCOR3,TTC17,IFT122,LIMCH1,MBD5,TMCC1,KDM4B,DOP1A,PDZD2,BDP1,FNBP1,NMNAT2,MYCBP2,SPTB,CDK19,TSPYL2,NFASC,LHPP,CLASP2,ZC4H2,LARP4,SSPO,ERBIN,ST5,PHLDB1,ARHGEF9,COBL,ASTN2,ANKRD12,CAMTA1,MCF2L,FBXW11,TBL1X,SMG6,MGRN1,ATMIN,TPCN2,PCDHGB1,FRYL,THRA,NACC2,ANKRD24,CSMD1,PARD3,KAT6B,TRIO,TRPM2,TRPS1,TTTY15,TTC3,UBE2H,SLC35A4,LMF1,ZNF708,ZNF189,DPYSL5,SPIRE1,MEIS3,INTS3,SLC30A4,MAP3K12,VPS35L,SEMA3B,WNK2,ST7,KAT6A,HNRNPA3,TMEM63C,JMJD1C,NETO1" Pubmed 17114649 Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Pubmed 8.05E-62 1.40E-56 4.67E-57 5.90E-56 128 330 "SYN3,XKR4,ELFN2,ADCY5,ADD1,ADD2,AP2A1,CASKIN1,TAOK1,BEGAIN,BIN1,PKP4,APC,BCAS1,MADD,ATP1A1,EIF4G3,STX16,ATP2A2,ATP2B2,ATP6V0A1,ADGRB3,HCN2,SYNJ1,ARHGEF7,CACNA1A,CACNA1B,CACNB4,CAMK2A,CAMK2B,CAMK2G,ARHGEF2,SEPT7,DCLK1,DLGAP1,NUMBL,EPS15L1,NGEF,NRG2,SIPA1L1,PITPNM3,ERC2,RIMS2,PPP6R2,DBN1,RUSC2,C2CD2L,SNAP91,DPYSL2,BAIAP2,AGAP2,NBEA,SPECC1,CAMKK2,ABLIM2,GABBR1,GABRA3,TMEM121B,PCLO,CIT,ATXN2L,SYNPO,SLC6A17,KCNB1,KCND2,STXBP5,L1CAM,STMN1,MAP2,MAP4,MAPT,MPP2,GIT1,ADAM22,SAMD14,MYO5A,NCAM2,NEFH,NF1,NRCAM,CLDN11,PALM,PDPK1,GNG2,PIK3C2A,PLEC,SH3KBP1,PPP3CA,PRKACB,PRKCB,MAPK10,BCAS3,PTK2,TMEM145,IQSEC3,OXR1,RASGRF1,RTN1,HSPA4L,CPEB3,MYO18A,CNKSR2,CCDC92,ABLIM3,EPN2,RADIL,ARFGAP1,MYCBP2,TEX2,SPTAN1,STXBP1,PLCB1,SYN1,SYN2,ADGRL3,DMXL2,DOCK9,PHF24,RIMBP2,MTCH1,TOM1L2,CLIP2,NDRG4,DHX33,SLC30A3,ITM2C,RTN4,JPH3" Pubmed 24952961 A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Pubmed 8.79E-60 1.53E-54 3.82E-55 4.83E-54 330 1835 "ASIC1,ACHE,AXIN2,FZD9,ADORA2A,UNC5A,MTA3,PCDH19,AGT,SEMA6A,ALCAM,PCDH10,ALK,TRMT9B,AMH,SEMA7A,APBA2,APC,APLP1,VAT1L,SEMA4G,SPTBN4,ARNTL,NCOA1,NUMB,ATP1A1,BACH1,BCHE,CFLAR,PROM1,BMP7,BMPR1B,JAZF1,CACNA1G,BAIAP3,CACNA1A,CACNA1B,DDR1,CACNA2D1,CALB1,CALB2,HAP1,CAMK2A,RUNX1T1,ARHGEF25,CCK,LDB2,CERS5,SCARB1,CDH2,KCNAB3,LARGE1,ZNF445,NOG,CRLF1,CHRNA4,SLIT2,LHX2,NGEF,FAM189A2,VAX2,CNR1,CNTN1,WHRN,COL4A5,COL9A1,LETMD1,COL9A3,COL11A2,MAGED1,AHCTF1,NRG2,NECTIN3,CLOCK,C1QL2,NCOR1,NCOR2,GDA,CRYM,AATK,CSF1,CSF1R,CSNK1E,CST3,PLXNA4,PYGO1,BOC,MAML1,DBI,TIAM2,LYPD1,DLX1,GRIN3A,MED12,SLC29A4,NR1D2,CDON,E2F5,E2F6,EBF1,EDNRB,HEYL,SEMA3D,CELSR3,APH1A,EGFR,PLXNC1,EMX2,EPHB1,ERBB2,ERBB4,APC2,ETV1,ADGRV1,NRN1,TUBB3,PPP1R1B,FGF1,FGF12,FGF14,FGFR1,FGFR3,SCARA3,FOXO3,EVL,SEMA4D,FLT1,DLL3,FYN,GABBR1,GABRA3,CHL1,GABRB3,GABRG1,GABRG2,GAD1,DISC1,IGSF5,GDF1,MSTN,GDF9,GFRA2,CSDC2,PPARGC1A,NTNG2,TOX3,GLUL,KCNMB4,MCHR1,GPR37,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,PRDM5,GRM8,CIT,KAT7,TOX2,ZHX1,BACH2,HLF,HNF4G,SOWAHA,IGF1,NKD1,ZIC5,RBPJ,IL6ST,INPP1,LRRTM1,ITGAM,CDH20,KCND2,KCNQ3,KIT,L1CAM,LIFR,LIMS1,SMAD1,SMAD9,MAP2,MAPT,MBP,MEF2C,MEIS2,MEST,KITLG,MITF,MYCN,LAYN,MYT1,NCAM2,NEFH,NF1,NFE2L2,NFIX,NFYA,NNAT,NPY,NRCAM,NTRK2,NTRK3,CLDN11,OXTR,P2RX7,CNTN3,PAX6,PDE1C,SEMA5B,PIK3R1,PKD1,NLE1,PLCD1,PCDH18,PLXNB1,NECAB2,POU6F1,IRX1,PPARA,LRRN3,PPP3CA,PRKCB,MAPK9,MAPK10,PRODH,RELN,PSD,LAMA1,PTCH1,PTK2,QDPR,RASGRF1,RASGRF2,CRTAC1,ZMAT4,RET,RGS4,PBRM1,ZFHX4,LGI2,ROBO1,ROBO2,RORB,EPHA10,FBXW7,LRRK2,RXRA,S100B,SEMA6D,SATB1,SGK1,ARX,FNDC3A,PKNOX2,SLC6A11,SLC12A2,LGI3,CXXC4,ABTB1,SNCA,PDZD2,SOX11,ZHX3,MYCBP2,SPP1,UNC5B,PEG10,NFASC,CLSTN2,CAMTA2,POGZ,SST,SSTR1,SSTR2,STX1A,SYN1,ARC,SYT1,ASTN2,TACR1,CAMTA1,TAF6,TAF9,TAL1,TCF4,SATB2,CUX2,ZEB1,TCF12,NSD1,PCDHA7,HIF3A,TEK,ZFPM2,GPR161,THRA,TIAM1,HEY1,ICAM5,NR2E1,PARD3,NR2C2,TRPS1,TSC1,TSC2,RPRM,UBE3A,UBTF,MGAT5B,VGF,VIPR2,PCDH20,ZIC1,ZIC2,ZNF24,ZNF189,DPYSL5,LAMP5,MEIS3,EVI5,SEMA3B,SLC17A7,KCNAB1,FZD3,ST7,PHTF2" Pubmed 12693553 Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 6.24E-54 1.08E-48 2.17E-49 2.74E-48 131 395 "KLHL32,ADCY6,RNF157,PLEKHH1,USP31,UNC5A,LRFN2,KLHL13,PCDH19,MARCH4,PCDH10,LRCH2,EP400,VAT1L,TNRC6C,MADD,IGDCC4,CADPS,MARK4,CCAR2,MTMR3,BAIAP3,CAMK2A,LARGE1,CLTC,WHRN,SEC24C,SIPA1L1,PDE4DIP,DZIP3,ERC2,ARHGEF4,PUM1,RUBCN,DOCK4,RIPOR2,SNPH,ZFYVE16,IST1,DGKB,SPOCK2,SPATA2,MFAP3L,RUSC2,C2CD2L,KIAA0319,ZC3H11A,SV2B,SGSM2,SEC16A,FEM1B,SUGP2,VPS13B,SPEG,CHST15,ANKFY1,CAMKK2,MEGF11,SEPT9,WASHC2A,USP19,PRRC2B,GRB10,NEGR1,DISP2,STXBP5,MARK3,NEFH,NRCAM,OPA1,PPP2R5E,KANSL1,RIPOR1,IQSEC3,LGI2,SETD5,SEMA6D,FNIP1,SCAF8,PPM1E,FRMPD1,R3HDM2,CNKSR2,NLGN1,DHX30,WDR47,BTBD7,MAST1,LIMCH1,MAPKBP1,FAIM2,USP33,PDZD2,FNBP1,ZHX3,ERC1,ZNF423,CDK19,ZBTB43,DDN,CAMTA2,POGZ,ERBIN,PHLDB1,KANK1,JMJD6,PRRC2C,ARHGEF9,COBL,ANKRD12,MTCL1,CAMTA1,MCF2L,ADGRL3,KIAA1107,AGTPBP1,ATMIN,CLASP1,SYNE1,DOCK9,PHF24,PUM2,RIMBP2,R3HDM1,TRO,TSC1,FSTL5,SMARCAD1,NAV3,SPATA13,SENP7" Pubmed 15226823 Genomic analysis of mouse retinal development. Pubmed 3.83E-41 6.66E-36 1.11E-36 1.40E-35 192 961 "FZD9,MTUS1,SORCS2,SPARCL1,FAM135A,PITPNM2,BIN1,LCORL,APC,DDO,SEMA4G,CADPS,NCOA1,CCAR2,BBS2,RGS9,BMP7,DDR1,LDB2,USP2,C1orf52,DCLK1,ZMYM4,LARGE1,COPB2,CHGB,TAOK2,SLIT2,LHX2,CLTB,LETMD1,ZNF385A,RBM39,CRHBP,NCOR1,NCOR2,CLIP3,CRYM,PDE4DIP,FAM169A,PITPNM3,GREB1,PUM1,SV2B,DMTF1,DTNA,EBF1,SEZ6L2,PHC2,FEM1B,MBNL2,EIF5,TMEM35A,EPB41,EPB41L2,GPHN,ERCC2,NCALD,EZH1,TUBA1B,PRMT5,FGFR1,FGFR3,IP6K2,EVL,ANKFY1,NOP56,OGA,GABBR1,GABRB3,CPLX2,CPLX1,WASHC2A,CYP46A1,GLYR1,GLUL,CBX1,GNAO1,PRRC2B,GPR37,GRB10,COQ10A,TOX2,ACOT7,TCEAL6,SHISAL1,NKD1,RBPJ,NIM1K,KCNQ3,KIT,TTYH2,STMN1,SMAD1,MAN2A2,MAP2,MARK3,MAT2A,MBNL1,MEST,KITLG,SCAMP5,MPP2,COMMD5,PTOV1,SAMD14,MYCN,NNAT,CNOT4,NPY,PCBP3,PAX6,DUSP26,SERPINI1,PIK3R1,PKD1,KCTD15,PLEC,SEPT4,POLR2F,DIRAS2,DEF8,SNRK,PTK2,NKAIN1,RAP1GDS1,ZMAT4,RNASEL,ZFHX4,CARF,ROBO1,RORB,ELP2,PCMTD2,RPL15,ATAT1,RTN1,SATB1,SCP2,HES6,ZNF821,RASA3,SGK1,HKDC1,PPP4R3A,SLC6A11,SEPHS1,CDK5RAP3,NAPB,LGI3,EPC1,ZKSCAN3,MAST1,SNAP25,USP33,SPATA7,SOX11,ZSWIM8,ERBIN,ELOVL4,STX1A,STXBP1,ZC3H4,SYT1,MMS19,MCF2L,SIN3B,TCF12,USP22,NSD1,FRYL,TMPO,PIK3R5,SMUG1,TSC1,FAM155A,USP1,PLPPR2,VIPR2,WNT7A,NPDC1,ZNF24,ZFP41,NDRG4,ZNF184,LAMP5,ZFAND5,GDPD5,PRDM8,NAV3,SLC17A7,FZD3" Pubmed 11544199 Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Pubmed 5.48E-41 9.53E-36 1.36E-36 1.72E-35 190 947 "KLHL32,INTS2,TAOK1,FAM135A,APC,SHROOM2,MADD,TMEFF1,ZBTB10,SYNJ1,BAIAP3,PTBP2,ARHGEF1,ENTPD6,DCLK1,ZNF445,COPB2,CNOT8,PLAA,CLTC,FBXO7,ARHGEF6,ARMC8,AKAP6,COL4A5,AHCTF1,FAM171B,AKAP12,CRMP1,SEC24C,CSNK1E,OSBPL3,CSNK1G3,SIPA1L1,VCAN,SOCS5,DZIP3,KIAA0040,PUM1,MYADM,GAPVD1,TCAF1,RIPOR2,MATR3,SPOCK2,DCTN1,ZBTB24,TIAM2,KIAA0753,ZC3H11A,ALKBH8,SEC16A,DMTF1,PDCD6IP,FARSB,DNM1L,FEM1B,KLHL5,EIF4G2,IRAK4,PAN3,VPS13B,LRRC17,SLC43A2,MRPL10,RPS6KC1,TAOK3,RACK1,FECH,POLK,SUCO,NOP56,FLYWCH1,DOT1L,ZMAT1,RAPGEF6,IQGAP2,GCNT2,ARFIP1,WASHC2A,PPARGC1A,BRD8,SPIN1,GLYR1,ZNF638,FERMT2,CNTRL,DIDO1,ZNF496,KAT7,AP4S1,FAM107A,PACSIN2,MAN1B1,NCKAP1L,ICA1,IFI16,RBPJ,FAM69A,KIF2A,LIMS1,PAXBP1,MAP4,MAP6,MARK1,MBNL1,MEST,MKLN1,AFF1,DBNL,ALDH1L2,P2RX7,PDE4B,NLGN3,PIK3R1,ZNF655,CCSER2,FAM216A,PLEC,PCDH18,SMIM7,PLXNB1,EXOSC10,EPB41L4B,FA2H,POLG,PPP2R5E,EPDR1,DEF8,PTCH1,ANKHD1,PTPN13,EML5,RAD17,SETD5,RPL15,ZNF821,SH3GL3,FRMPD1,SHMT2,FBXO11,ST6GAL1,SEC31A,ANKRD6,ABLIM3,CDK5RAP3,TET1,ARFGAP1,OGDHL,CDK5RAP2,KIF13A,LMBRD1,FNBP1,UHRF1BP1L,TEX2,ARHGAP26,CLASP2,CAMTA2,ERBIN,SEPT8,TTBK2,SYT1,ANKRD12,PJA1,CAMTA1,FAM208A,TCEA1,DOCK9,NSD1,CRTC1,FRYL,CHST8,SLC44A1,CBX5,PARD3,TP53BP1,STXBP4,TTC3,UBC,UBTF,TOM1L2,CLDND1,RICTOR,ZNF24,ZNF32,SPIRE1,TFIP11,VPS35L,PHTF2,FXR1" Pubmed 28706196 Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. Pubmed 1.60E-37 2.78E-32 3.47E-33 4.39E-32 88 259 "RALGAPA1,ACTN1,AP2A1,AP2A2,KCTD16,BEGAIN,PITPNM2,AMPH,PKP4,KCNAB2,ADGRB2,SYNJ1,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2G,SEPT7,DCLK1,DLGAP2,DLGAP1,NUMBL,CLTC,CNRIP1,CRMP1,GDA,SIPA1L1,APPL1,RIMS2,ARHGAP32,DBN1,DNM1,DYNC1I1,SHANK1,DPYSL2,DNM1L,EPB41L2,GPHN,PTK2B,BAIAP2,AGAP2,NBEA,CAMKK2,IQGAP2,GLUL,GNAO1,PCLO,GRIA2,GRIN2D,GRM2,CIT,GSN,SYNPO,SHISA6,ITPKA,MAP6,GIT1,ADAM22,MYO5A,NCAM2,NF1,NRCAM,NTRK3,OPA1,NLGN3,PLCL1,PPP3CA,PRKACB,PRKCB,MAPK3,MAPK10,PTK2,IQSEC3,PPM1E,CNKSR2,NLGN1,FAM81A,SPTAN1,IQSEC2,DDN,STXBP1,ARC,DMXL2,SYNE1,SIK3,TP53BP2,TRIO,ANKS1B" Pubmed 16169070 A human protein-protein interaction network: a resource for annotating the proteome. Pubmed 1.89E-36 3.28E-31 3.64E-32 4.61E-31 263 1678 "ABCF1,AP2A1,CEP126,BBOX1,BIN1,LRFN1,PKP4,APLP1,FAM131A,ARHGDIA,ARRB2,ARSE,CADPS,MARK4,DYNLL1,ATP1A1,ALDH7A1,ADGRB2,BCS1L,ARHGEF7,FUBP1,NAE1,SGCE,IL33,CA8,CA12,DDR1,CACNB4,HAP1,CBR1,MAGI1,TBRG4,CHGB,CHN1,CHN2,MS4A7,CPNE6,CLTB,CLTC,NGEF,COL4A5,SUMF2,MAGED1,TBPL1,CRMP1,SNCAIP,PHACTR3,RASGEF1C,BOC,GPRASP1,ZNF337,INTS1,DBI,DBN1,DCTN1,RUSC2,GSDME,POM121,PLPPR4,SGSM2,TMCC2,FAM107B,DNM1,DMPK,PDCD6IP,DNM1L,EDN1,PHC2,EEF1D,CELSR3,EGFR,RASA4,EIF4G1,IRAK4,TNK2,EIF1,ENO2,RASGRP2,MRPL10,PIPOX,ZNF585B,SH3YL1,TUBB3,CORO2B,RACK1,FDFT1,PRMT5,PPP1R1B,FGFR3,BAIAP2,ATP5PD,MEX3B,VTI1B,IQCG,FLYWCH1,NELFCD,DCTN2,NBEA,STAMBP,TRIM16,ATP6V1H,KHDRBS3,CELF1,STAU2,SARAF,OGA,GABBR1,HIGD1B,SEPT9,SRCAP,GDF9,NFU1,GFER,SPIN1,CBX1,HTATSF1,LOXL3,GNAO1,GPD1,ADAP1,STMN2,SPACA9,GRIK5,GSN,KAT7,ZBTB45,LINGO1,FAM107A,HBA1,ZHX1,FRMD5,DDX19B,GABARAPL2,HMGCL,EID2B,IDH3B,LRRCC1,INPP1,INSM1,KCNH2,GATD1,KIF5A,L1CAM,MAN2A2,MAP4,MARK3,ADAM11,GIT1,MSI1,PTOV1,MYO6,MYO9A,NACA,NOVA1,OGG1,PDPK1,OLA1,CCSER2,PKM,KCTD15,RETREG2,FSD1,PPARA,PPP5C,MAPK9,MAPK10,PRPSAP2,NDUFS7,PSD,PSMA6,GDPD2,ANKHD1,SPDL1,PTN,PTPRO,PEX2,ROGDI,ENOX1,BEND5,MSANTD2,GAL3ST4,PRRT2,SLC25A36,ROBO1,ROBO2,RPL15,FBXW7,PLPPR3,RXRA,SAFB,ATXN2,TRA2B,PUF60,SH3BP2,SH3GL3,CCDC92,SYBU,SLA,WDR47,KANSL3,SEPHS1,RADIL,ARHGEF40,CDK5RAP3,KBTBD4,ARFGAP1,SMARCC2,CDK5RAP2,SNAP25,SNRPN,KDM4B,USP33,FAM219A,SPP1,SPTAN1,ITPRID2,APOM,STX1A,SEPT3,NSFL1C,SUPT5H,NUDT10,SYN1,SYT1,SYT5,PJA1,TAF9,EXOC7,FAM208A,TCF12,USP22,SLC35G2,ITGB3BP,AKTIP,TMEM9,ANKRD24,TP53BP1,TP53BP2,WBP2,TRIO,HSPBP1,TUBB2A,UBC,UBTF,UCHL1,WNT7A,KLC2,GUSBP1,XRCC4,ZNF24,TRIM9,DPYSL5,UPF3A,MAP3K12,DNALI1,TUBA1A,URM1,ITM2C,NELFE,RTN4,ACTR3B,FXR1,RNF146" Pubmed 16713569 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Pubmed 6.69E-36 1.16E-30 1.16E-31 1.47E-30 138 608 "ACTN1,ADCY6,ADORA1,C1QTNF1,LTBP4,PDZD4,BEGAIN,PPFIA4,KCNAB2,GAS7,CHRD,ATP1A3,CACNA1G,KALRN,HAP1,PTBP2,RUNX1T1,USP6,CBFA2T2,ENTPD6,ZBED1,NUMBL,QKI,FHL5,PICK1,MAGED1,RCHY1,PREPL,NCOR1,PDE4DIP,CST3,DZIP3,PUM1,PPP6R2,ARHGAP32,TCAF1,TBC1D5,MATR3,IST1,ZNF804A,POM121,SACS,DMPK,DTNA,EDN1,PHC2,SUGP2,EPB41L2,BAIAP2,UBE2E3,PDLIM5,FYN,MEGF11,TMEM8B,SYT17,AHDC1,PCDH17,RUNDC3A,ZNF276,RNPS1,LNX1,PRRC2B,CLASRP,ZHX1,ATXN2L,ACOT7,IDH3B,KPNA5,STMN1,MATN2,MBD1,MBP,NELL2,NOVA1,PCBP3,PCDH8,PCSK5,NECAB2,FA2H,VSTM2L,EPDR1,APTX,QRICH1,ANKHD1,PTN,PTPRN,PTPRN2,FAT4,BEND5,UBR7,ROBO2,YY1AP1,ST6GALNAC6,ATXN2,ATXN7,SUPT20H,PUF60,SH3GL3,MYO18A,R3HDM2,SYBU,RADIL,GKAP1,SMARCC2,MAPKBP1,ZHX3,ZSWIM8,HECW1,SPP1,ZNF423,TSPYL2,LMO3,SSPO,STAC2,TAF9,AGTPBP1,TNS2,ZFPM2,TMPO,R3HDM1,KAT6B,TP53BP2,IL34,ELP5,TRO,STXBP4,HSPBP1,EIF4ENIF1,UBE3A,CCDC136,CCDC14,VSNL1,LAT2,KLC2,XRCC4,PCBP4,WNK2,KAT6A" Pubmed 27507650 Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Pubmed 4.19E-35 7.29E-30 6.63E-31 8.38E-30 82 241 "ABR,TMEM132B,CASKIN1,BEGAIN,KCNAB2,SPTBN4,ADGRB2,ADGRB3,MPDZ,SYNJ1,ARHGEF7,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2G,SEPT7,DCLK1,DLGAP2,DLGAP1,TAOK2,HOMER3,CNTN1,CNRIP1,GDA,ERC2,ARHGAP32,DCTN1,DNM1,SHANK1,DPYSL2,EPB41L2,RACK1,BAIAP2,AGAP2,NBEA,IQGAP2,GLUL,GNAO1,TPPP,GRIA2,GRIK5,GRIN2D,CIT,GSN,SYNPO,KCNJ16,MPP2,GIT1,ADAM22,MYO5A,NEFH,PDE4B,NLGN3,PLCL1,SH3KBP1,PPP3CA,PRKACB,PRKCB,MAPK3,PTK2,IQSEC3,RPS6KA2,CNKSR2,FAM81A,SPTAN1,IQSEC2,DDN,NFASC,ERBIN,MPRIP,SEPT3,PLCB1,SYN1,ARC,SYT1,DMXL2,SYNE1,TRIO,ANKS1B,KCNAB1,NETO1" Pubmed 17081983 "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Pubmed 1.02E-34 1.77E-29 1.47E-30 1.86E-29 245 1546 "ABCF1,CLK4,ACTN1,ELFN2,ADD1,OSBPL1A,OSBPL8,TAOK1,ZNF687,BEGAIN,AMPD2,BIN1,ANK2,ARMC12,PKP4,APAF1,APC,USP37,SHROOM2,PRX,SPTBN4,CDK13,NUMB,CCAR2,EIF4G3,ATP2A2,MPDZ,PROM1,KSR1,DST,ARHGEF7,CACNA1B,CAMK2G,CAST,SPAG9,CERS5,CCNH,C1orf52,LRBA,SEPT7,KCNAB3,LRRFIP1,CLGN,NUMBL,CFL2,COPB2,SRSF11,CBARP,EPS15L1,NRXN3,TMEM184B,CNN3,ARHGEF6,AHCTF1,CDC42BPB,RBM39,AKAP12,NCOR1,NCOR2,CSNK1E,SIPA1L1,PHF14,PUM1,RIMS2,USP6NL,HDAC9,MATR3,SPOCK2,GIT2,DBN1,YTHDC1,ELMSAN1,RUSC2,C2CD2L,ZC3H11A,DDX46,POM121,WDR20,SEC16A,MED12,TOM1,DNAJB6,EEF1D,OPTN,YAF2,EGFR,PLXNC1,EIF4G1,EIF5,TNK2,STARD3NL,VPS13B,SRRM1,ERBB2,NSRP1,RPS6KC1,SEC24B,SEMA4D,NOP56,SPECC1,PDLIM5,KHDRBS3,ZNF44,RAPGEF6,SEPT9,BRD8,RNPS1,ZNF638,CBX1,KIAA1958,HTATSF1,FERMT2,ADGRA3,PRRC2B,PRUNE2,DIDO1,CIT,CLASRP,KAT7,PACSIN2,ATXN2L,SYNPO,AGFG1,IL6ST,IPO5,STXBP5,KTN1,L1CAM,STMN1,PAXBP1,SYTL4,SMAD9,MAP2,MAP4,MBP,MIA2,MID1,AFDN,MOV10,GIT1,DBNL,HNRNPM,NINJ2,CHAMP1,PALM,PDE4D,PDPK1,PKD1,XRN1,PKM,PLEC,MAPKAP1,RETREG2,SH3KBP1,MAPK3,PRPSAP2,VPS13C,TMEM104,PTK2,PTPRB,OXR1,RBBP6,DPF2,REV3L,PBRM1,CCDC82,ROBO1,CCDC25,CLIP1,RMI1,SAFB,MAPK12,CASC3,TRA2B,SCAF8,MYO18A,CHD9,FNDC3A,ABLIM3,EPN2,ATF7IP,SMARCA4,MAST1,SMARCC2,CDK5RAP2,SMARCD3,MYH15,RCOR3,TMCC1,RBM34,FAM219A,MYCBP2,ZC3H13,SPTAN1,RBM26,POGZ,ITPRID2,ERBIN,ST5,MPRIP,PHLDB1,NSFL1C,ZC3H4,SUPT5H,SYNE2,TACC1,MTCL1,TAF9,TCEA1,ZEB1,SYNE1,PUM2,SLC35G2,SIRT1,ZNF106,CBX5,LRRC8A,TMPO,PARD3,KAT6B,TNS1,TP53BP1,TP53BP2,TRIO,TRPS1,TSC2,UBC,BCL2L13,TBC1D15,CLIP2,KLC2,KCNK12,ZNF142,ZBTB38,TFIP11,SMARCAD1,TUBA1A,FIP1L1,NELFE,RTN4,KAT6A,TTC7A,FXR1,GAN,SENP7" Pubmed 14621295 Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.82E-32 3.16E-27 2.43E-28 3.08E-27 119 508 "RALGAPA1,MTA3,ZNF608,INTS2,MTUS1,HECW2,CASKIN1,CEP126,ARHGAP20,CARNS1,SYT13,ZNF687,PITPNM2,CDC42BPA,EP400,PHF12,ZFYVE28,ADGRB3,SYNJ2,ARHGEF7,CACNA1G,HIP1R,ZMYM4,TBRG4,TAOK2,MAP4K4,AKAP6,CLOCK,PREPL,CNTNAP2,RIMS2,USP6NL,GAPVD1,EARS2,KIF26A,MATR3,MAML1,SCRN1,HEPH,MYEF2,TIAM2,DDX46,PLPPR4,CASP8AP2,PDCD6IP,CELSR3,ERBB2,ADGRV1,MED12L,AMOTL2,FLYWCH1,CAMKK2,HHIPL1,OGA,DENND2A,SRRM4,KIAA1841,TNRC6A,KDM2B,DIDO1,PADI2,SYNPO,SHISAL1,NACA,CHAMP1,PALM,SEMA5B,CCSER2,PLXNB1,SDK2,VPS13C,SNRK,ANKHD1,ERI2,ROBO2,SBF1,KIF21A,KIF16B,AMBRA1,FNDC3A,DZIP1,WDR37,KANSL3,CCDC88A,TET1,CDK5RAP2,FAIM2,KDM4B,KDM3A,NMNAT2,TEX2,ARHGAP26,NFASC,POGZ,ZC4H2,SEPT8,SULF2,ZC3H4,PLCB1,DNMBP,IQCE,SMG6,MGRN1,SATB2,ZFP90,SZT2,CRTC1,PCDHA3,SIK3,DICER1,LRRC8A,TRIM9,NDRG4,SH3GLB2,SPIRE1,STOX2,HPS4,WNK2,RTN4" Pubmed 25921289 Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Pubmed 2.24E-32 3.89E-27 2.78E-28 3.51E-27 278 1922 "ABCF1,ACADM,ACTN1,FMNL2,ADD1,KIAA1211,ESYT2,AP2A1,AP2A2,KLHL13,WDR35,OSBPL8,AK2,TAOK1,ALCAM,ABCD2,AMPD2,OGT,CDC42BPA,ANK2,MAP4K3,PARG,EPB41L5,LGR5,MADD,CASK,ARHGDIA,CDK13,CCAR2,ATP1A1,ATP1A3,EIF4G3,ATP2A2,ATP6V0A1,KIF1A,ARHGEF7,FUBP1,NAE1,AP1M1,WASF1,CARS,HIP1R,SPAG9,CBR1,CBS,CCNT1,ARHGEF1,ARHGEF2,CDH2,LRRFIP1,LRWD1,TBRG4,CLGN,COPB2,SRSF11,EPS15L1,PLAA,CLTC,QKI,MAP4K4,CNN3,MAGED1,SMARCAL1,CDC42BPB,RBM39,CRMP1,ANKRD44,CS,SEC24C,CSNK1E,PLXNA4,APPL1,PUM1,PPP6R2,GPSM1,DOCK4,ARHGAP32,GAPVD1,TCAF1,EARS2,TBC1D5,MATR3,INTS1,DBN1,DCTN1,MYEF2,ELMO1,ZC3H11A,GSDME,DDX46,SEC16A,DNM1,MED12,DPYSL2,PDCD6IP,TOM1,DNAJB6,FARSB,DNM1L,SEZ6L2,EEF1D,EGFR,RASA4,EIF4G1,EIF4G2,EIF5,COPS4,DCTN4,ENO2,EPB41,GPHN,SRRM1,ERCC2,MRPL37,TUBB3,RACK1,PRMT5,SEC24B,POLR1B,SEC23B,SYNCRIP,AGAP3,ANKFY1,NELFCD,DCTN2,SMC2,PDLIM5,ATP2C1,MPP6,OGA,GAA,SEPT9,WASHC2A,USP19,TCERG1,HTATSF1,GNAO1,FERMT2,GPD2,MAP4K5,ATXN2L,ACOT7,IDH3B,GAREM2,KCNH2,KIF2A,IPO5,KTN1,L1CAM,LSS,MAP2,MAP4,MARK3,MAT2A,SHC3,AFDN,MOV10,GIT1,DBNL,THYN1,MYO5A,MYO6,NACA,HNRNPM,NRCAM,NTRK3,OCRL,OPA1,PCDHGC3,PDE4B,FAM98B,OLA1,ABCB1,PIK3C2A,PIK3R1,XRN1,PKM,STRN3,PSAT1,EXOSC10,FSD1,LRRN3,PPP5C,PRKACB,MAPK7,PRPSAP2,PSMA6,QRICH1,PTK2,EML5,CEP97,USP47,RAP1GDS1,RDX,RET,RNH1,EXD2,ELP2,RPL15,MCMBP,SAFB,SARS,SBF1,ATXN2,TRA2B,HSPA4L,PUF60,SCAF8,KIF21A,PPM1E,SHMT2,SEC31A,PPP4R3A,DHX30,ARHGEF40,CCDC88A,SLC12A2,SMARCA4,SMARCC2,IFT122,LIMCH1,SNRPN,ZSWIM8,UNC5B,SPTAN1,RBM26,CLASP2,TROVE2,LARP4,STAU1,PHLDB1,STXBP1,ZC3H4,SUPT5H,PRRC2C,DNAJC9,SYT1,ANKRD28,MMS19,TAF6,EXOC7,TCF4,TCF12,CLASP1,SYNE1,PCDHB3,PUM2,DICER1,LRRC8A,TMPO,SYNPO2,TRIO,TSC2,HSPBP1,UBC,UBE3A,UBTF,UCHL1,VGF,TBC1D15,WRN,KLC2,XPO1,DPYSL5,TFIP11,SMARCAD1,INTS3,TUBA1A,VPS35L,FIP1L1,NELFE,RTN4,HNRNPA3,AAAS,FXR1,AP3B2,LAS1L,PRRT4" Pubmed 16452087 Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Pubmed 1.76E-31 3.05E-26 2.04E-27 2.57E-26 73 214 "ABCF1,SYN3,ELFN2,ADD1,ADD2,CASKIN1,BEGAIN,PKP4,BCAS1,PPFIA3,FUBP1,CACNA1B,CACNB4,CAMK2B,CAMK2G,DCLK1,ARHGAP33,EPS15L1,NGEF,QKI,HOMER3,RBM39,SIPA1L1,RIMS2,FAM131B,MATR3,C2CD2L,DYNC1I1,DPYSL2,EPB41L2,GPHN,SPEG,PTK2B,AGAP2,RGPD5,NOP56,ABLIM2,GABBR1,PRRC2B,PCLO,TPPP,GRIN2D,CIT,PSIP1,SYNPO,KCNB1,MAP2,MAPT,MARK1,MBP,MYO5A,ZDHHC8,PURG,SEPT4,PRKCB,IQSEC3,RPS20,CNKSR2,SMARCC2,FNBP1,SPTAN1,CLASP2,MPRIP,SEPT8,STX1A,SEPT3,SYN1,CLASP1,TIAM1,TMPO,TSC2,GJC2,JPH3" Pubmed 21900206 A directed protein interaction network for investigating intracellular signal transduction. Pubmed 3.42E-30 5.94E-25 3.71E-26 4.69E-25 189 1123 "CCDC85A,ADD1,TBC1D14,TAOK1,CEP126,GPRASP2,AMPH,LRFN1,LCORL,PKP4,APBA2,APLP1,APOC1,SPTBN4,ARHGDIA,DYNLL1,TMEM108,EIF4G3,BCS1L,BID,CA12,DDR1,HAP1,SPAG9,CBS,ARHGEF1,ENTPD6,ZBED1,UBE2L6,CHGB,CHN1,CHRNA4,CNOT8,CPNE6,NGEF,ARHGEF6,CNTFR,CNTN1,ARMC8,COL4A5,ANKRD35,COL11A2,ZFP28,AKAP12,CRMP1,CRYM,SNCAIP,CSNK1E,PDE4DIP,PHACTR3,UBXN2A,KIAA0408,MATR3,DBI,DBN1,DCTN1,TIAM2,FBXL5,DNM1,DMPK,DYNC1I1,DPYSL2,PDCD6IP,PHC2,KLHL5,EIF4G1,EIF1,RABEPK,MRPL37,VPS26C,TUBA1B,TUBB3,RACK1,FHL1,MEX3B,HPCAL4,IQCG,FOXO3,DCTN2,UFM1,FAM49B,ZNF605,OGA,FYN,INPP5K,TUBGCP4,GDF9,ADAP1,STMN2,GRB10,SPACA9,KAT7,PSIP1,MAP4K5,HBA1,ZHX1,NXPH3,MAN1B1,GABARAPL2,HMGCL,IDH3B,RBPJ,INPP1,KLHL23,KIF5A,STMN1,SMAD1,MAP4,SHC3,MEST,MPP2,GIT1,BLOC1S2,NELL2,NOVA1,PCDH8,PDE1B,PDPK1,PFKFB4,SEMA5B,CCSER2,PKM,PSAT1,RETREG2,MBOAT7,SH3KBP1,PPP3CA,PPP5C,MAPK3,MAPK9,PRPH,MASP1,PTK2,PTN,PTPRO,RIPOR1,ROBO2,YY1AP1,ZNF671,RXRA,ZNF331,RMI1,SAFB,SBF1,SH3GL3,SEC31A,SLA,ARFGAP1,ZNF667,SNCA,FAM219A,SPTAN1,STAU1,SEPT8,SEPT3,NSFL1C,SYNE2,SYT5,MCF2L,KIAA1107,FBXW11,TCF4,USP22,ITGB3BP,SLC44A1,CBX5,TNS1,TP53BP2,RUNDC3B,TSC2,TTC3,ZKSCAN5,TUBB2A,UBC,UBE3A,GORASP1,OSBP2,CCDC136,VAV1,KLC2,CFAP298,TCEAL7,MAP3K12,DNALI1,TUBA1A,CIAPIN1,RTN4,JMJD1C,ADAMTS10" Pubmed 27626380 High-throughput discovery of novel developmental phenotypes. Pubmed 3.75E-30 6.52E-25 3.83E-26 4.85E-25 243 1633 "SYN3,C3orf14,ELFN2,RNF157,ESYT2,PTCHD1,LRFN2,SLC24A4,AP2A2,CASKIN1,HACE1,KIAA1324,ADGRF5,SPOP,BBOX1,DPP10,PKP4,CPNE5,AQP6,ZFYVE28,ARRB1,ARRB2,TMEM108,ATP1A3,STX16,ATP2A2,ATP6V0A1,ADAM23,BACH1,SYNJ1,NAE1,JAZF1,CACNA1I,GPC2,IL33,LDLRAD4,CA4,CACNA1B,VXN,CAST,CH25H,HIP1R,RHBDL1,CCK,KRIT1,CERS5,USP2,P2RX6,SCARB1,AP4M1,KCNAB3,ARHGAP33,CHN1,PPT2,ABCG2,TMEM184B,HECTD1,CNR1,COX4I1,HAPLN1,CRYM,CS,ARHGEF10,GREB1,GPSM1,CYBB,BOC,SNPH,DAPK1,AIF1L,DBN1,SPATA2,ZBTB24,KIAA0753,KLHL3,USP3,DNM1L,SEZ6L2,SNX29,HEYL,EIF4G2,EPB41,NCALD,SPEG,PIPOX,ADGRV1,EZH1,CLVS1,ABCA8,PRAM1,SLC9B2,FGFR1,BAIAP2,HPCAL4,RGPD5,FOXO3,EVL,SEMA4D,CINP,FAM49B,KHDRBS3,NSG1,HHIPL1,FYB1,GALC,IQGAP2,SYT17,GATM,ALDH1L1,GHR,TOX3,GNAO1,GP1BB,TDRKH,TPPP,PARD3B,ADAMTS13,ZNF496,BVES,RABL2A,RASSF8,PADI2,FRMD5,PACSIN2,GABARAPL2,NEGR1,HSF2,IRF8,IL6R,IL6ST,INPP1,KCNB1,LIFR,HECTD2,NCOA7,LSS,MAPT,LYPLAL1,MAT2A,CHST6,POC1B,MMP16,BLOC1S2,MYO9A,TCEAL5,NEFH,NRCAM,NTRK2,IGSF11,OXTR,P2RX7,PCSK1,PCSK5,PDCD2,PDE1B,PFKFB2,PFKFB4,PIK3C2A,KCTD15,GPSM2,FAM216A,PLCB2,PCDH18,PRIMPOL,MAPKAP1,STRN3,MBOAT7,EPB41L4B,TATDN3,PPP2R2B,PRKAB2,PKIA,EPDR1,PRODH,NDUFS7,VPS13C,USP47,SH3TC2,IQSEC3,RDX,RIC8B,CARF,GSTCD,SNX22,NEK11,EPHA10,SGSM1,RTN1,SATB1,CASC3,SH3BP2,MYO18A,ANKRD6,NUBPL,SLC2A5,PEX26,DHX30,MAPKBP1,LMBRD1,ZHX3,DBNDD2,TSPYL2,THSD1,SST,DIP2A,JMJD6,RHBDL3,VPS13A,DNAJC9,SYPL1,ADGRL3,IQCE,SATB2,TPCN2,USP22,DICER1,SIRT1,CHST8,AP4E1,AKTIP,SLC44A1,ARL10,THRA,NACC2,PARD3,ZNF346,SYNPO2,NUTM2A,SSBP2,TST,UBE2H,ELFN1,NDRG4,LYPD6,FTSJ1,DHX33,GDPD5,PRDM10,ITM2C,PARP11,FZD3,FBXO36,IFT88" Pubmed 15368895 Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 5.62E-30 9.76E-25 5.43E-26 6.86E-25 110 471 "NDRG2,FMNL2,ELFN2,GALNT16,CCDC85A,PWWP2A,AP2A2,KIAA1324,WDR35,OSBPL8,TXNDC16,TAOK1,ADGRF5,FAM135A,EPB41L5,GAS7,USP37,SEMA4G,PRX,PPP4R4,CDK13,DNAH17,SCAPER,THSD7A,SPAG9,DIS3L,HECTD1,SLC4A8,ZFP28,CDC42BPB,SH2B1,CRY2,GDA,OSBPL3,SOCS5,FAM169A,SLITRK5,APPL1,PHF14,PPP6R2,HDAC9,ARHGAP32,TCAF1,RASSF2,KIAA0586,IP6K1,ARMCX2,YTHDC1,KIAA0753,POM121,RHOBTB1,TMCC2,GRIN3A,MED12,DOCK2,ABCA8,MEX3B,PCYOX1,ATP2C1,NEURL4,ACSS1,TTBK1,PRUNE2,LRRCC1,SCIN,MARK1,MOV10,MYO6,NEK1,NLGN3,PCDH18,PDZRN4,SH3TC2,ATP8B4,SEC14L1,ZFP30,ANKRD6,ABLIM3,PPP4R3A,EPN2,FAM214B,RADIL,CPEB4,MBD5,TMCC1,PDZRN3,DOP1A,SP2,HECW1,KDM4C,CEP68,RGL1,ASTN2,EXOC7,FAM208A,SIN3B,DMXL2,KIAA0930,FAM189A1,GPRIN3,BHLHB9,ANKRD24,ZKSCAN5,FLRT2,PLEKHH2,CLIP2,RICTOR,ADAMTS9,JMJD1C,RSPRY1" Pubmed 12168954 Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. Pubmed 6.93E-30 1.20E-24 6.34E-26 8.01E-25 73 225 "ADCY6,ESYT2,AP2A2,ZNF608,WDR35,OSBPL8,APAF1,TNRC6C,PPFIA3,CADPS,ADGRB3,DST,SYNJ1,CACNA1G,BAIAP3,THSD7A,SPAG9,AKAP6,CDC42BPB,AATK,ARHGEF10,SIPA1L1,PPP1R16B,ERC2,APPL1,ARHGEF4,SCRN1,GIT2,ZBTB24,HEPH,C2CD2L,TMCC2,SEC16A,CASP8AP2,ADGRV1,ANKFY1,CAMKK2,OGA,ERAP1,NTNG2,PRUNE2,SNRK,FNDC3A,KDM4B,ZHX3,HECW1,MYCBP2,ERC1,CDK19,NFASC,ERBIN,CEP68,PHLDB1,SULF2,ZC3H4,SYNE2,PLCB1,ANKRD28,CAMTA1,SMG6,DMXL2,CUX2,SYNE1,DOCK9,OBSL1,PUM2,SIK3,DICER1,KAT6B,CLIP2,TRIM9,NDRG4,TTC7A" Pubmed 11230166 Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Pubmed 1.17E-29 2.03E-24 1.01E-25 1.28E-24 145 750 "NDRG2,KIAA1211,AP2A1,INTS2,ADGRF5,FAM135A,SYT13,BIN1,C6orf89,USP37,CCAR2,TMEM108,NAE1,GPC2,BAIAP3,ZNF555,CAST,ENTPD6,ARHGEF2,CNOT8,PPT2,CLCN3,SOCS5,PNPLA8,ARHGAP24,AIF1L,DBN1,ELMO1,FBXL5,TMEM130,FAM107B,RAB39B,CD99L2,ECM2,DNAJB6,GOLT1B,AASDH,FCF1,EIF5,MRNIP,ELN,EMX2,COQ7,NCALD,ADGRV1,CD320,NSRP1,FAM198B,ZMYND10,MEX3B,HPCAL4,RGPD5,IQCG,ZMYND15,PSD2,SLC37A3,FLYWCH1,SYT3,JKAMP,PDLIM5,MSANTD4,MPP6,GALNT15,BRD8,SPIN1,ADAMTS13,FAM107A,PACSIN2,DDX19B,MIER3,ELOVL5,SYNPO,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MITF,MMP16,MOV10,MPP2,PCSK5,GPR85,OLA1,ABCB1,PDZRN4,RETREG2,KANSL1,ANKHD1,MTMR10,RAD17,FAM184A,ZCWPW1,ROGDI,TRIM68,ZDHHC4,ALG9,PNMA8A,YY1AP1,PLPPR3,FAM192A,AP1AR,DGLUCY,SEC14L1,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,RADIL,ELMO2,LIMCH1,SPATA7,ZC3H13,TSPYL2,POGZ,STAU1,SEPT3,KLHL7,SYNE2,TCF12,SLC35G2,SIRT1,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,SSBP2,PLEKHH2,USP1,KLC2,NDRG4,SPHK2,TFIP11,CIAPIN1,VPS35L,FIP1L1,ITM2C,PHTF2,TIGD6,RNF170,RNF146,SENP7" Pubmed 21832049 "Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein." Pubmed 1.18E-28 2.05E-23 9.76E-25 1.23E-23 265 1891 "DGCR6,ABCF1,ABR,FMNL2,KLHL32,ADD2,DPY19L2P4,AP2A2,PDZD4,BEGAIN,BIN1,EPB41L5,PHYHD1,VAT1L,PLA2G4C,ASGR1,MARCH3,STK33,ZSCAN18,NUMB,RASL11B,CHID1,ALDH7A1,BMPR1B,BTK,GYG2,CARS,KYAT1,USP6,USP2,P2RX6,CBFA2T2,KCNAB3,DCLK1,L3MBTL4,CHGB,RAB28,STOML1,QKI,LY86,RAB26,HOMER3,PCYT1B,LETMD1,GAL3ST1,TBPL1,COX4I1,RBM39,HAPLN1,TRIM69,MROH8,SEC24C,CSNK1E,SOCS5,RIMS4,PPP6R2,USP6NL,ARHGAP24,HDAC4,ZFYVE16,SPATA2,GUCD1,TMCC2,DMD,RCAN1,TOM1,DNAJB6,E2F6,TSPAN5,HEYL,FSD1L,PHF20L1,EIF5,TMEM35A,EIF1,EPB41L2,RASGRP2,IGSF6,SPEG,CDKL3,MRPL10,RASL12,RRAGB,NSRP1,ACSL4,ST3GAL6,FCGR3A,GORAB,OLFM1,FGF12,BAIAP2,ATP5PD,SYNCRIP,TMEM175,CINP,TRIM16,CAMKK2,CELF1,HRASLS5,SYT17,SEPT9,CPLX2,KIAA1841,MSTN,AHDC1,MSL3,AIFM3,POLL,RAB40B,FERMT2,GPT2,LNX1,PRRC2B,GPR12,TPPP,GRB10,DIDO1,PLCD4,ANKRD36BP1,CLASRP,KAT7,AP4S1,GUCY1B1,RASSF8,TOX2,DDX19B,VSIG4,GABARAPL2,AGFG1,SMAP1,IFI16,RBPJ,NIM1K,INPP5B,KCNN3,GATD1,KIFC3,PACRG,SMAD1,ZFYVE27,MAP2,MBD1,MBNL1,MEIS2,MEST,MITF,MSI1,BLOC1S2,MX1,MXI1,NDP,NFYA,NNAT,NOVA1,SMIM11A,NTRK3,OPA1,PCDHGC3,CDK18,PDE4D,PDPK1,TMOD2,CCSER2,RETREG1,PKM,PLCD1,PSAT1,ING3,POLR2F,C19orf57,PPP2R5E,PPP3CC,PPP5C,MAPK7,MAPK10,PRPSAP2,PIGG,PTK2,PTPRO,PEX2,TMEM255A,CCDC40,FAM184A,BEND5,ZMAT4,GTDC1,RGS3,MRPS18A,PBRM1,DCUN1D2,CARF,PNMA8A,MRAP2,NEK11,TCP11L1,RPS20,ATAT1,NCBP3,DGLUCY,COPZ1,RASA3,SHMT2,FNDC3A,LIMS2,FAM214B,ARHGEF40,ARFGAP1,CXXC4,RCOR3,LIMCH1,SNAP25,SNCA,FAM126B,SPATA7,TSNAXIP1,SP2,NMNAT2,TEX2,ERC1,SPART,POGZ,SSTR2,LARP4,NXT2,STAU1,RGL1,STXBP1,NECAB1,TAF6,TAF9,TCEA1,KIAA0930,PCDHGC5,ARHGAP9,PCDHA7,TEK,ITGB3BP,ZMAT3,MTMR14,BHLHB9,PIK3R5,NPL,RUSC1,KCNE5,HSPBP1,SGK3,UBE3A,BCL2L13,TOM1L2,CCDC14,VIPR2,KLC2,CFAP298,ZNF23,CELF4,ANKS1B,FTSJ1,ZFAND5,UPF3A,INTS3,DNALI1,KCNAB1,FIP1L1,PDSS2,HRASLS" Pubmed 24154525 Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Pubmed 3.33E-28 5.79E-23 2.63E-24 3.33E-23 90 348 "SEMA6A,ALCAM,DPP10,CPNE5,SEMA4G,IGDCC4,CADPS,CALB2,PRC1,CBS,ENTPD2,KCNAB3,CACNA2D2,PLEKHB1,LHX2,QKI,CNN3,CNR1,COL9A3,HAPLN1,CNTNAP2,CST3,DBI,ZNF804A,ELMO1,DLX1,EGFR,RCAN2,MTSS1L,ERBB4,ADGRV1,ST3GAL6,FGF12,FGFR1,CSPG5,MEGF10,GAA,GAD1,ACSS1,CPLX1,GLUL,STMN2,CIT,PTPRT,GSN,PADI2,IGFBPL1,IRF8,IGF1,KIT,STMN1,LSAMP,MBP,TM6SF1,MSI1,MYCN,NEFH,NNAT,NPY,NTRK2,CLDN11,PDE3A,SLC10A4,SERPINI1,PLTP,PSAT1,NECAB2,SEPT4,RASGEF1B,RELN,PTN,PTPRN,PTX3,RGS12,LGI2,ROBO1,PLPPR3,ATAT1,ST6GAL1,SLC8A1,SLC14A1,MYO16,SOX11,CUX2,NACC2,HSPBP1,DPYSL5,LAMP5,NETO1,SPATA13" Pubmed 20936779 A human MAP kinase interactome. Pubmed 4.04E-28 7.03E-23 3.06E-24 3.86E-23 109 486 "NCKAP5,ACTN1,FMNL2,CDC42BPA,MAP4K3,APC,GAS7,MADD,ARHGDIA,ARRB1,ARRB2,SLC4A4,RIPK1,PROM1,DST,SYNJ2,ARHGEF7,BTK,ARHGEF1,ARHGAP33,MAGI1,DLGAP1,CLTC,MAP4K4,ABI3BP,CDC42BPB,ARHGEF4,PYGO1,HDAC9,ARHGAP32,RIPOR2,HDAC4,KIF26A,ELMSAN1,DCTN1,POM121,DMD,SHANK1,CASP8AP2,PDCD6IP,HIPK3,TNK2,EPB41L2,BAIAP2,FLNC,DCTN2,STAMBP,ABLIM2,TCERG1,TNRC6A,GLUL,CNTRL,MAP4K5,ZHX1,PACSIN2,SYNPO,AGFG1,KIF5A,KTN1,MEF2C,MYO6,MYO9A,HNRNPM,NFYA,PIK3R1,PLEC,KANSL1,PRKAR1B,MAPK7,MAPK9,MAPK10,PTK2,RAP1GDS1,RBBP6,ROBO1,YY1AP1,SUPT20H,MYO18A,CCDC92,SEC31A,PPP4R3A,CCDC88A,ATF7IP,MBD5,SPTAN1,POGZ,ITPRID2,SS18,ERBIN,RGL1,ARHGEF9,PLCB1,COBL,SYNE1,CRTC1,SIK3,ZNF106,ANKRD24,TNS1,SYNPO2,UBC,TOM1L2,CCDC14,WIPF1,CLIP2,ZNF142,HPS4,NAV3,WNK2" Pubmed 15342556 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Pubmed 1.39E-27 2.41E-22 1.00E-23 1.27E-22 189 1177 "KLHL13,SYT13,APC,GAS7,CDC14B,ARSE,ZNF583,ATP6V1G2,RIPK1,BCS1L,BLM,DST,SYNJ1,MTMR2,CACNB4,ZNF501,CCNH,SLC16A4,SEPT7,DIS3L,SRSF11,FOXN3,TAOK2,CLCN3,TPP1,AKAP6,SUMF2,RCHY1,GAL3ST1,COX4I1,CPS1,CREM,MROH8,VCAN,PDE4DIP,RIMS2,GPRASP1,DCAF8,DAPK1,SPOCK2,DBI,HEPH,TIAM2,LYPD1,WDR20,CHRDL1,DYNC1I1,CASP8AP2,DPYSL2,DNM1L,E2F5,FSD1L,GOLGA7,ING4,ELN,RCAN2,SIRPB1,EXTL2,GMPR2,DLC1,FKTN,KAT8,TMEM164,SEC23B,IP6K2,COQ5,POMT1,SPECC1,HVCN1,APOPT1,UFM1,PDLIM5,FYB1,SDCBP2,ERAP1,SIGLEC8,ZNF559,PCDH17,DHRS4,RAB30,ZNF638,GNAL,LILRA2,GRIA2,PLCD4,FAM107A,IRAK3,VSIG4,SYNPO,CPT1C,LIFR,SYTL4,MEF2C,SRSF12,ZNF92,MYH3,NCF2,NEFM,NF1,NFIX,NME4,PALM,PDE1B,NLGN3,KCTD15,NLE1,PLCL1,PLEC,ZNF426,PRIMPOL,SH3KBP1,PPARA,PPP1R1A,PPP2R2B,NKAIN4,HYDIN,KLK6,SNRK,SPDL1,PEX2,DPF2,REV3L,RGS3,KCTD17,CCDC82,ROBO1,TCP11L1,PTGR2,ATAT1,NCBP3,FAM192A,RMI1,SALL1,SARS,ATXN7,SH3GL3,CNKSR2,NUBPL,ABLIM3,PEX26,LIMS2,KANSL3,ZFP1,COA1,OGDHL,RCOR3,INAVA,BDP1,UNC5B,PEG10,DBNDD2,SPTAN1,MESP1,ZC4H2,ERBIN,RGL1,KANK1,SUPT5H,ARHGEF9,ANKRD12,TCF4,TPCN2,CYB561A3,DNAH7,DICER1,ZNF34,HEY1,CBX5,CSMD1,TP53BP1,ELP5,TSN,TTC3,UBTF,UCHL1,CCDC14,WRN,KLC2,RICTOR,TMEM237,ZNF177,ANKS1B,EVI5,PRDM8,VPS35L,PLSCR4,KAT6A,PHTF2,SPATA13" Pubmed 15302935 Large-scale characterization of HeLa cell nuclear phosphoproteins. Pubmed 1.00E-26 1.74E-21 6.95E-23 8.79E-22 142 773 "ABCF1,ADCY6,ADD1,ESYT2,TAOK1,ZNF687,BIN1,EP400,PHF12,PARG,CDK13,CCAR2,ATP2A2,BACH1,BLM,FUBP1,CAST,SPAG9,CBFA2T2,ARHGEF2,ZMYM4,LRRFIP1,CDO1,LRWD1,EPS15L1,CLTC,MAP4K4,ARHGEF6,IQCK,NCOR1,NCOR2,SEC24C,CSNK1E,SIPA1L1,APPL1,PHF14,GAPVD1,MATR3,DBN1,YTHDC1,ZC3H11A,DDX46,SEC16A,PHC2,FAM13A,SUGP2,EGFR,EIF4G1,EIF4G2,EPB41L2,SRRM1,SCML2,UBE2E3,EVL,TRIM16,OGA,RAPGEF6,SEPT9,USP19,BRD8,RNPS1,DBF4,MSL3,ZNF638,KIAA1958,KDM2B,DIDO1,CLASRP,PSIP1,ZHX1,ATXN2L,IFI16,TJAP1,PAXBP1,MAP4,MAPT,MATK,AFF1,AFDN,MN1,GIT1,MYCN,NF1,CHAMP1,PDPK1,PLEC,STRN3,KANSL1,MAPK3,RIPOR1,USP47,RBBP6,RBBP8,DPF2,YY1AP1,CLIP1,SAFB,ATXN7,SCAF8,MYO18A,PPP4R3A,KANSL3,ARFGAP1,SMARCA4,SMARCC2,LIMCH1,FAM126B,KDM4B,TRERF1,FNBP1,KDM3A,ZHX3,MYCBP2,ZC3H13,SPTAN1,POGZ,ITPRID2,ERBIN,NSFL1C,ZC3H4,TAF6,DNMBP,AGTPBP1,TCEA1,ZEB1,CLASP1,PUM2,SIRT1,ZNF106,TMPO,PARD3,KAT6B,TP53BP1,KLC2,RICTOR,XPO1,TFIP11,SMARCAD1,INTS3,EMSY,FIP1L1,NELFE" Pubmed 15618518 Mouse brain organization revealed through direct genome-scale TF expression analysis. Pubmed 4.30E-26 7.48E-21 2.88E-22 3.64E-21 238 1689 "KDM5D,NDRG3,NDRG2,RNF157,BRAP,MTA3,OSBPL6,ZNF687,ZFAT,LCORL,PHF12,ARNTL,NCOA1,ATP1A1,ZNF583,KIF1A,BACH1,BARD1,SCAPER,JAZF1,LDB2,CERS5,ZMYM4,ZNF445,CNOT8,LHX2,VAX2,FHL5,CNN3,TBPL1,AHCTF1,ZNF521,ZFP28,ZNF385A,CLOCK,CREM,RNF14,HINFP,NCOR1,CLIP3,TRIM69,PHF14,PYGO1,ZFYVE16,ZNF804A,ZBTB24,RHOBTB1,DLX1,NR1D2,DMTF1,E2F5,E2F6,EBF1,HEYL,KLHL5,PHF20L1,MBNL2,EGR3,PLXNC1,EIF5,COPS4,ING4,EMX2,ETV1,FHL1,FOXF2,FOXO3,ANKFY1,PDLIM5,STAMBP,TRIM16,ABLIM2,ZMAT1,ZNF274,SRCAP,BRD8,ZNF276,DBF4,GLI2,GLYR1,TOX3,ZNF638,STMN2,DIDO1,PRDM5,ZNF496,KAT7,ZBTB49,SOX21,ATOH8,ZHX1,BACH2,HNF4G,ZDHHC15,HSF2,IRF8,ZNF546,ZIC5,INSM1,LIMS1,LMO2,SMAD1,SMAD9,ZFYVE27,MBD1,MBNL1,MEF2C,MEIS2,MID1,MITF,AFDN,MXI1,MYCN,MYT1,NFE2L2,NFIX,NFYA,CNOT4,CHAMP1,PAX6,ZNF655,ZNF426,ING3,POU6F1,IRX1,PPARA,QRICH1,ZIK1,PEX2,ZSCAN2,ROGDI,TRIM68,DPF2,RET,RFX2,RFX3,ZDHHC4,UBR7,PBRM1,ZFHX4,RORB,FBXW7,ZNF354C,RXRA,SALL1,SATB1,HES6,ZFP2,ZNF821,ZFP30,ARX,FBXO11,DZIP1,LIMS2,PKNOX2,KDM4D,ZNF334,BTBD7,ZKSCAN3,ZFP1,ZNF667,SMARCA4,SMARCD3,PDZRN3,KDM4B,TRERF1,SOX3,SOX11,SOX15,KDM3A,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,RBM26,POGZ,MESP1,JMJD6,SUPT5H,PJA1,TAF6,TAL1,MGRN1,TCEA1,TCF4,SIN3B,SATB2,ZFP90,CUX2,ZEB1,TRIM2,TCF12,NSD1,HIF3A,ZFPM2,ZMAT3,ZNF106,THRA,HEY1,NR2E1,NR2C2,ZNF346,TRPS1,ZKSCAN5,UBTF,VAV1,ZFP37,ZBTB14,ZIC1,ZIC2,ZNF711,ZNF23,ZNF24,TRIM9,ZFP41,ATP6V0E2,NDRG4,MKRN3,SPHK2,ZNF142,ZBTB38,ZNF184,ZNF189,ZNF213,ZFAND5,MEIS3,EVI5,PRDM8,RNF103,NAV3,RTN4,KAT6A,JMJD1C,ZDHHC20,DPF3,RNF146" Pubmed 16189514 Towards a proteome-scale map of the human protein-protein interaction network. Pubmed 7.98E-25 1.39E-19 5.14E-21 6.49E-20 223 1573 "ACTN1,FZD9,AGT,NME5,C1QTNF1,SPOP,BEGAIN,OGT,UPRT,SEMA4G,ARRB1,ASPA,RASL11B,ADAM15,BBS2,AP1M1,GYG2,LURAP1,CALM1,PTBP2,CAPN3,RUNX1T1,PRC1,CBS,CCNH,USP2,CBFA2T2,ZBED1,EVI5L,CFL2,RCBTB2,CNOT8,RAB33A,FAM189A2,QKI,HOMER3,FHL5,CNTFR,HINFP,TRIM69,SEC24C,CSNK1E,APPL1,CTH,GPSM1,KIAA0408,TCAF1,DCAF8,ZNF337,TBC1D5,MATR3,IST1,IP6K1,PITPNC1,SPATA2,JAKMIP2,ZBTB24,ZC3H11A,POM121,PARD6A,DYNC1I1,DTNB,E2F6,PHC2,HEYL,EEF1D,OPTN,EBI3,COPS4,HSD17B14,NCALD,KATNAL1,SH3YL1,RACK1,ZMYND10,BAIAP2,AMOTL2,HPCAL4,SEC23B,IP6K2,VTI1B,DCTN2,C2orf88,CINP,PDLIM5,STAMBP,KHDRBS3,SDCBP2,TRAF3IP2,GAD1,FAM120B,ZNF559,SYT17,INPP5K,TUBGCP4,RUNDC3A,NTNG2,ZNF276,TXNL4A,RNPS1,GLUL,ZNF638,POLL,LNX1,PRRC2B,PRUNE2,STMN2,DIDO1,PLCD4,SERP2,ANKRD36BP1,ZNF496,CLASRP,KAT7,LINGO1,FAM107A,RASSF8,PACSIN2,GABARAPL2,ITPKB,LIMS1,LMO2,SYTL4,SMAD9,MARK3,MATK,DBNL,MXI1,HNRNPM,NFYA,NME4,PCSK5,CDK18,ZNF655,NLE1,ZNF426,MAPKAP1,NECAB2,C19orf57,PPARA,PPP3CA,KANSL1,MAPK9,PRPH,WDR25,PTK2,ZSCAN32,RAP1GDS1,ENOX1,BEND5,RBBP8,KHDRBS2,RFX2,RFX3,KCTD17,SETD5,CARF,YY1AP1,RPE,SNX22,BAALC,ZC3H14,MCMBP,KCNIP3,RTN1,CCDC112,S100B,SATB1,ZNF821,PUF60,FUZ,WDR37,PEX26,FAM214B,SEPHS1,RADIL,ZNF334,GKAP1,RCOR3,SNAP25,DOK5,SPP1,DBNDD2,ZBTB43,LMO3,PBLD,ZC4H2,NXT2,ARC,TAF9,EXOC7,NEU4,TRIM2,ARHGAP9,FRYL,C18orf54,ITGB3BP,AKTIP,CBX5,FAM124A,TPM1,SMUG1,SSBP2,HSPBP1,UBC,EIF4ENIF1,BCL2L13,CCDC14,VSNL1,NPDC1,XRCC4,ZNF24,TRIM9,SH3GLB2,PRTFDC1,CIAPIN1,FIP1L1,ITM2C,PLSCR4,PARP11,FAM13C,RTN4,FRMD6" Pubmed 27173435 An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Pubmed 1.20E-24 2.09E-19 7.46E-21 9.44E-20 197 1321 "ABCF1,ACTN1,FMNL2,ADCY6,AP2A1,AP2A2,RTL9,OSBPL1A,OSBPL6,WDR35,AMPD2,LRFN1,OGT,LRCH2,ARHGDIA,ARNTL,NUMB,CCAR2,DYNLL1,ATP2B2,BACH1,BBS2,BLM,KSR1,WASF1,CFAP410,CALM1,CAMK2A,CAMK2B,SPAG9,CBS,SEPT7,CDC25B,DCLK1,LARGE1,MAGI1,CLGN,NUMBL,SLIT2,EPS15L1,RAB28,MYL6B,CLTB,TMEM184B,ARHGEF6,ARMC8,WHRN,CLOCK,AKAP12,CS,OSBPL3,SIPA1L1,DZIP3,APPL1,CCDC144A,GAPVD1,HDAC4,MAML1,GIT2,DCTN1,POM121,WDR20,SEC16A,E2F5,KCTD3,COPS4,STARD3NL,C8orf37,PAN3,DCTN4,GPHN,DENND4A,ZMYND10,FECH,SEC24B,BAIAP2,ATP5PD,VTI1B,SYNCRIP,AGAP3,FOXO3,DCTN2,WDR83,SMC2,UFM1,USP21,NEURL4,TRAF3IP2,GALC,IQGAP2,TUBGCP4,MMADHC,COPS8,ZNF638,POLL,FERMT2,PRRC2B,GSN,CLASRP,RASSF8,ELOVL5,HSPA1L,SOWAHA,KTN1,PACRG,SMAD9,MBNL1,SRSF12,MKLN1,AFDN,MOV10,GIT1,BLOC1S2,PTOV1,MYO7A,NEFM,NEK1,NF1,TBC1D25,OCRL,OPA1,PCDH9,CDK18,PFKFB2,OLA1,PIK3R1,PLEC,MAPKAP1,MBOAT7,PPP2R5E,PTPN13,EML5,PTPRG,RIPOR1,TMEM231,CEP97,CCDC40,RADX,RFX3,KIF7,RNH1,SETD5,TCP11L1,CLIP1,COPZ1,FUZ,SHMT2,AMBRA1,PPP4R3A,EPN2,DHX30,CCDC88A,GKAP1,IFT122,SPATA7,UHRF1BP1L,MYCBP2,ERC1,ARHGAP26,IQSEC2,CLASP2,MPRIP,NEK4,KLHL7,SUPT5H,DNAJC9,ANKRD28,MLST8,EXOC7,KIAA0930,RPGRIP1L,CLASP1,OBSL1,CRTC1,DICER1,TIAM1,PARD3,TP53BP1,TP53BP2,CDK20,TSC2,SSBP2,HSPBP1,TUBB1,EIF4ENIF1,UBE2H,WRN,XRCC4,TMEM237,DPYSL5,SPIRE1,DNALI1,UBE3B,RSPRY1,IFT88,GAN,LAS1L" Pubmed 8619474 "A ""double adaptor"" method for improved shotgun library construction." Pubmed 2.31E-24 4.02E-19 1.39E-20 1.75E-19 113 569 "ASPHD1,ADD2,MARCH4,BIN1,OGT,ANK2,APBA2,APC,MARCH3,CHRD,KIF1A,ADAM23,BCS1L,BAIAP3,ZNF555,CAMK2B,RUNX1T1,METTL6,DCLK1,ARHGAP22,FAM19A5,COX4I1,ABCG1,RIMS2,HDAC4,MATR3,ZNF804A,FBXL5,GSDME,SNAP91,SV2B,DNM1,DMTF1,RCAN1,DTNB,SEZ6L2,WDPCP,ANKRD46,OPTN,PLXNC1,EPB41L2,STX2,ERBB4,NCALD,CEP85L,ETV1,REEP2,OLFM1,IP6K2,EVL,STAMBP,SDCBP2,TMEM8B,AHDC1,MMADHC,CSDC2,MALT1,RUNDC3A,NTNG2,GPD2,FAM107A,PACSIN2,ATXN2L,HLF,ELOVL5,C2orf72,HECTD2,MAP4,MMP16,PTOV1,SAMD14,NF1,NTRK3,CCSER2,FAM216A,PLTP,SCHIP1,NECAB2,MAPK10,WBP1L,RGS3,LGI2,MEG3,RXRA,SEC14L1,ZNF821,STUM,ST6GAL1,SIRT2,ZNF415,KDM4B,FAM219A,SPP1,PEG10,NFASC,LARP4,SUPT5H,VPS13A,MMS19,KIAA0930,PCDHB10,OBSL1,DICER1,CDH22,TIAM1,MTMR14,BHLHB9,TMPO,UBC,TOM1L2,ZIC1,NDRG4,FAM13C" Pubmed 8125298 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Pubmed 2.48E-24 4.31E-19 1.44E-20 1.82E-19 252 1883 "ACHE,ABHD6,AS3MT,ACTN1,ADCY6,ADRB2,AP2A2,AGT,SPOP,FAM135A,GAS7,APOC1,BCAS1,CDC14B,ARSE,CDK13,ZSCAN18,CHID1,ATP1A3,EIF4G3,ATP6V0A1,BARD1,BCS1L,PROM1,BTK,RAB29,CALB2,CAMK2B,CAMK2G,CARS,NFS1,LDB2,RGN,SLC16A4,SEPT7,TBRG4,FOXN3,CHGB,CPNE6,PLAA,TPP1,STOML1,FHL5,PICK1,LETMD1,NSL1,CLOCK,CRHBP,CSNK1E,CTH,PUM1,DCAF8,RASSF2,GIT2,DBN1,TMEM130,WDR20,DNM1,DPYSL2,DTNB,DNAJB6,E2F6,EEF1D,EGFR,KMT5B,AASS,ASB3,EIF4G2,COPS4,TNK2,PCOLCE2,ELN,TMEM35A,VPS13B,COQ7,LRRC17,IGSF6,ANKMY1,CD320,REEP2,ARMCX1,TUBB3,DLC1,RACK1,ZMYND10,FCGR3A,KAT8,PPP1R1B,FECH,GTF2IRD2,FGFR1,BAIAP2,AMOTL2,FHL1,PCYOX1,SYNCRIP,ANKFY1,DCTN2,FOLR2,COQ5,WDR83,ZBED3,APOPT1,SARAF,GABBR1,GALNT15,ZNF274,IP6K3,ERAP1,MTHFD2,GATM,ALDH1L1,ADAM28,GGT5,RUNDC3A,BRD8,STARD3,HTATSF1,TDRKH,LILRA2,PLCD4,SLC2A6,HBA1,FRMD3,DDX19B,HSF2,HSPA1L,SMAP1,IDH3A,TJAP1,IL6R,LRRTM1,KCNJ16,KHK,IPO5,MATK,MBD1,TM6SF1,MOV10,MPP2,N6AMT1,SAMD14,MX1,NACA,P2RX7,ZNF827,PCSK5,PDPK1,OLA1,PIK3R1,ZNF655,RETREG1,PKM,KCTD15,PLTP,MTRF1L,NKAIN4,PPP5C,MAPK10,DCHS2,NDUFS7,SAMD9,BCAS3,CYBC1,PPP2R3C,QDPR,CEP97,USP47,HKR1,GAL3ST4,PRRT2,ZDHHC4,RGS3,C12orf49,ALG9,CARF,GSTCD,YY1AP1,ELP2,CCDC102B,FBXW7,ZNF671,ATAT1,NCBP3,DGLUCY,SARS,SUPT20H,COPZ1,SH3BP2,FERMT1,SHMT2,FBXO11,CCDC92,SEC31A,ABLIM3,WDR47,SIRT2,CDK5RAP3,MTERF2,ARFGAP1,OGDHL,INTS9,IFT122,SNAP25,KIF13A,LMBRD1,SNRPN,USP33,SPATA7,ZC4H2,NSFL1C,MMS19,PCDHB7,CYB561A3,AKTIP,HEY1,ACTR6,TPM2,SMUG1,ELP5,PDSS1,NEIL2,AMACR,TRO,KCNE5,TSN,TST,SGK3,UGT8,MTCH1,PLPPR2,VAV1,VGF,TBC1D15,LMF1,LAT2,NPDC1,CFAP298,ZNF225,INTS3,PRTFDC1,DNALI1,SLC38A1,ITM2C,PCBP4,MPPE1,PDSS2,PHTF2,RNF170,AAAS,FXR1,LAS1L" Pubmed 26638075 A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Pubmed 5.10E-24 8.87E-19 2.86E-20 3.62E-19 245 1820 "RALGAPA1,ASIC1,C3orf14,XKR4,ADD1,ESYT2,AP2A1,MTUS1,RTL9,OSBPL8,TXNDC16,CC2D2A,AK2,SEMA6A,OGT,ANK2,PKP4,APC,EPB41L5,TNRC6C,CASK,ARRB2,NUMB,CCAR2,DYNLL1,CHID1,ATP1A1,STX16,ATP2A2,DPY19L3,ATP6V0A1,KIF1A,SEC11C,BLM,DST,CFAP410,CACNA1A,CALM1,CAMK2B,PRC1,SCARB1,LRBA,ARHGEF2,DCLK1,CLGN,COPB2,CBARP,CLTC,HECTD1,MAP4K4,AKAP5,MAGED1,RTTN,FAM171B,AKAP12,NCOR1,SEC24C,CSNK1E,SIPA1L1,APPL1,USP6NL,TBC1D5,LIN54,MATR3,KIAA0586,DAPK3,DBT,SPATA2,DCTN1,MYEF2,KIAA0753,WDR20,SEC16A,CD99L2,SLC12A6,DTNB,DNAJB6,ABCC5,GOLT1B,SUGP2,COPS4,TENM1,PLEKHA1,DCTN4,ENO2,MFSD10,CEP85L,REEP2,TUBA1B,GORAB,SEC24B,BAIAP2,SEC23B,FOXO3,DCTN2,WDR83,NBEA,SMC2,PDLIM5,ATP2C1,ERGIC3,AP4B1,OGA,NEURL4,RAPGEF6,TUBA8,ARFIP1,WASHC2A,TOX3,TNRC6A,HTATSF1,MAP7D2,DCLK2,GNAO1,FERMT2,PRRC2B,CNTRL,AP4S1,RASSF8,PACSIN2,DDX19B,HMGCR,AGFG1,DHX35,HSPA1L,IDH3B,LRRCC1,KIF2A,IPO5,KTN1,MAP2,MAPT,LYPLAL1,MARK3,POC1B,MYO9A,NACA,HNRNPM,NEK1,PCBP3,SLC11A2,NUCB2,OCRL,PALM,PIK3C2A,PIK3R1,CCSER2,RETREG1,XRN1,MBOAT7,FA2H,SH3KBP1,FSD1,PPP2R2B,CEP41,MAPK9,CNNM2,BCAS3,PTPN13,TTC13,PPP2R3C,CEP97,KIF7,RNH1,ALG9,KIRREL1,ZC3H14,CLIP1,NCBP3,CCDC112,TRA2B,COPZ1,HSPA4L,FNDC3A,CCDC92,SEC31A,EPN2,DHX30,SLC6A8,SIRT2,SLC12A2,SLC12A4,GKAP1,CDK5RAP2,INTS9,RCOR3,LIMCH1,PDZRN3,FAM219A,FNBP1,ZSWIM8,TEX2,ERC1,UNC5B,SPART,CLASP2,ERBIN,MPRIP,STAU1,NEK4,SUPT5H,ANKRD28,DNMBP,FAM208A,AGTPBP1,TBCEL,FBXW11,TRIM2,RPGRIP1L,USP22,CLASP1,DICER1,SIRT1,AP4E1,AKTIP,TMEM9,TMPO,PARD3,TP53BP2,METTL3,TRIO,STXBP4,HSPBP1,TUBB2A,EIF4ENIF1,UGT8,CCDC14,TBC1D15,KLC2,TRIM9,TMEM237,SH3GLB2,FTSJ1,TFIP11,SMARCAD1,EMSY,SLC38A1,TUBA1A,ITM2C,ST7,RTN4,ZDHHC20,AAAS,IFT88,NETO2" Pubmed 16381901 The LIFEdb database in 2006. Pubmed 7.47E-24 1.30E-18 4.06E-20 5.13E-19 130 720 "NDRG2,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,APOC1,USP37,CDK10,CCAR2,PROM1,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,CNOT8,PPT2,CLCN3,FBXO7,MROH8,LRRC3B,PNPLA8,USP6NL,AIF1L,DBN1,FBXL5,TMEM130,FAM107B,RAB39B,CD99L2,ECM2,DNAJB6,MRNIP,ELN,COQ7,NCALD,NSRP1,FAM198B,RACK1,ZMYND10,MEX3B,HPCAL4,PSD2,SYT3,JKAMP,PDLIM5,MSANTD4,GALNT15,SPIN1,CCDC184,FAM107A,MIER3,GABARAPL2,SYNPO,HSPA1L,ICA1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MOV10,NDP,PCSK5,GPR85,ABCB1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,FAM192A,AP1AR,DGLUCY,SEC14L1,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,KLC2,NDRG4,TFIP11,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,FXR1,RNF146,SENP7" Pubmed 15489336 From ORFeome to biology: a functional genomics pipeline. Pubmed 9.68E-24 1.68E-18 5.10E-20 6.45E-19 130 722 "NDRG2,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,APOC1,USP37,CDK10,CCAR2,PROM1,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,CNOT8,PPT2,CLCN3,FBXO7,MROH8,LRRC3B,PNPLA8,USP6NL,AIF1L,DBN1,FBXL5,TMEM130,FAM107B,RAB39B,CD99L2,ECM2,DNAJB6,MRNIP,ELN,COQ7,NCALD,NSRP1,FAM198B,RACK1,ZMYND10,MEX3B,HPCAL4,PSD2,SYT3,JKAMP,PDLIM5,MSANTD4,GALNT15,SPIN1,CCDC184,FAM107A,MIER3,GABARAPL2,SYNPO,HSPA1L,ICA1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MOV10,NDP,PCSK5,GPR85,ABCB1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,FAM192A,AP1AR,DGLUCY,SEC14L1,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,KLC2,NDRG4,TFIP11,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,FXR1,RNF146,SENP7" Pubmed 9110174 Large-scale concatenation cDNA sequencing. Pubmed 1.10E-23 1.91E-18 5.61E-20 7.09E-19 111 563 "ASPHD1,ADD2,MARCH4,BIN1,OGT,ANK2,APBA2,APC,MARCH3,CHRD,KIF1A,ADAM23,BCS1L,BAIAP3,ZNF555,CAMK2B,RUNX1T1,METTL6,DCLK1,FAM19A5,ABCG1,RIMS2,HDAC4,MATR3,ZNF804A,FBXL5,GSDME,SNAP91,SV2B,DNM1,DMTF1,RCAN1,DTNB,SEZ6L2,WDPCP,ANKRD46,OPTN,PLXNC1,EPB41L2,STX2,ERBB4,NCALD,CEP85L,ETV1,REEP2,OLFM1,IP6K2,EVL,STAMBP,SDCBP2,TMEM8B,AHDC1,MMADHC,CSDC2,MALT1,RUNDC3A,NTNG2,GPD2,FAM107A,PACSIN2,ATXN2L,HLF,ELOVL5,C2orf72,HECTD2,MAP4,MMP16,PTOV1,SAMD14,NF1,NTRK3,FAM216A,PLTP,SCHIP1,NECAB2,MAPK10,WBP1L,RGS3,LGI2,RPL15,MEG3,RXRA,SEC14L1,ZNF821,STUM,ST6GAL1,SIRT2,ZNF415,KDM4B,FAM219A,SPP1,PEG10,NFASC,LARP4,NSFL1C,SUPT5H,VPS13A,MMS19,KIAA0930,PCDHB10,OBSL1,DICER1,CDH22,MTMR14,BHLHB9,TMPO,UBC,TOM1L2,ZIC1,NDRG4,FAM13C" Pubmed 11076863 DNA cloning using in vitro site-specific recombination. Pubmed 1.25E-23 2.18E-18 6.22E-20 7.87E-19 138 794 "NDRG2,ADCY8,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,APC,APOC1,USP37,CDK10,CCAR2,HCN2,PROM1,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,CNOT8,PPT2,CLCN3,FBXO7,MROH8,LRRC3B,PNPLA8,USP6NL,AIF1L,DBN1,FBXL5,TMEM130,FAM107B,RAB39B,DMD,CD99L2,ECM2,DNAJB6,MRNIP,ELN,COQ7,NCALD,F5,NSRP1,FAM198B,RACK1,ZMYND10,MEX3B,HPCAL4,PSD2,SYT3,JKAMP,PDLIM5,CSPG5,MSANTD4,GALNT15,SPIN1,CCDC184,SOX21,FAM107A,MIER3,GABARAPL2,SYNPO,HSPA1L,ICA1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,ADAM11,MIA2,SCAMP5,MOV10,NDP,PCSK5,GPR85,ABCB1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,FAM192A,AP1AR,DGLUCY,SEC14L1,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,KLC2,NDRG4,TFIP11,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,FXR1,RNF146,SENP7" Pubmed 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 6.07E-23 1.06E-17 2.93E-19 3.71E-18 143 852 "KIAA1211,ESYT2,OGT,EP400,PARG,ZBTB10,CCAR2,BLM,WASF1,SPAG9,RUNX1T1,PRC1,LDB2,CBFA2T2,SYNGR3,ARHGEF2,ZMYM4,LRWD1,COPB2,FOXN3,ARMC8,SMARCAL1,CPS1,CREM,SH2B1,NCOR1,NCOR2,CTH,PUM1,GAPVD1,LIN54,MAML1,YTHDC1,DCTN1,MYEF2,ZC3H11A,DLX1,DUSP9,FARSB,E2F6,EEF1D,PHF20L1,SUGP2,EIF4G1,GPHN,ACSL4,FHL1,FOXF2,FOXO3,FLNC,FLYWCH1,NELFCD,SMC2,GAA,IQGAP2,BRD8,TCERG1,GLYR1,PSIP1,ACOT7,HSPA1L,RBPJ,KIT,KPNA5,KTN1,LIG4,SMAD9,MBD1,MEF2C,MEIS1,MOV10,MXI1,MYCN,NEFM,NFIX,NFYA,NOVA1,NOVA2,PKM,ING3,KANSL1,MAPK9,BCAS3,QRICH1,ANKHD1,USP47,ZCWPW1,REV3L,RFX2,RFX3,KIF7,MRPS18A,RNASEL,ZFHX4,RXRA,TRAPPC13,FAM192A,SALL1,SATB1,KIF27,PUF60,FRMPD1,FBXO11,WDR47,KANSL3,EPC1,SMARCA4,SMARCC2,FNBP1,RBM26,POGZ,PRRC2C,DNAJC9,ANKRD28,MMS19,TAF9,AGTPBP1,FBXW11,TBL1X,TCF4,SIN3B,SATB2,TCF12,OBSL1,NACC2,CABIN1,TP53BP1,TPM1,CDK20,TPM2,NR2C2,TRO,TRPS1,HIRA,ZIC2,SMARCAD1,INTS3,EMSY,PRDM10,TUBA1A,FIP1L1,JMJD1C,FXR1" Pubmed 23251661 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Pubmed 6.78E-23 1.18E-17 3.18E-19 4.03E-18 139 817 "ADCY5,GALNT13,LRFN2,SORCS2,CC2D2A,DPP10,PKP4,CA8,CACNA2D1,CAMK2A,CBS,CDH2,DCLK1,DLGAP1,CHN2,RAB28,CLTB,SRP14-AS1,WHRN,AATK,CSF1,SIPA1L1,RIMS4,CNTNAP2,UBXN2A,GREB1,USP6NL,HDAC9,ARHGAP24,SCRN1,DBI,YTHDC1,ZNF804A,PARD6A,SPOCK3,GRIN3A,DYNC1I1,EBF1,SNX29,WDPCP,EDNRA,MBNL2,ASB3,C8orf37,EMX2,TUBD1,ADGRV1,ZNF585B,DLC1,OLFM1,SPECC1,AK8,AP4B1,CHL1,SRRM4,CPLX2,PRDM5,FAM19A2,FICD,RNFT2,HAS2,NCKAP1L,BACH2,SHISA6,ICA1,IFI16,C2CD4C,CDH20,KCNB1,KLHL23,KCNN2,KCNN3,ASPRV1,MATK,SAMD5,LAYN,CCDC13,SETD4,IGSF11,PDE4D,FAM218A,KCTD15,PCDH18,ANKRD16,PSAT1,MBOAT7,DCHS2,BCAS3,SNRK,PTPRD,PTPRN2,SLC25A48,RBBP6,GTDC1,KIF7,RNASE1,CYB561D1,KIRREL1,LRRK2,FHOD3,BTBD3,PKNOX2,SLC8A1,RADIL,TRIM67,CPEB4,CABCOCO1,SNRPN,MYO16,PDZD2,BDP1,SOX11,NMNAT2,HECW1,KDM4C,SPTB,LHPP,SS18,MPRIP,ZC3H4,SYT1,ASTN2,FAM189A1,SLC19A3,TLR4,CSMD1,TSC2,FAM155A,UBE3A,RICTOR,AGMO,DPYSL5,ANKS1B,PRTFDC1,TMEM178A,DOCK8,PHTF2,ACTR3B,FAM198A" Pubmed 11125038 Database resources of the National Center for Biotechnology Information. Pubmed 1.19E-22 2.08E-17 5.46E-19 6.91E-18 221 1614 "KCNH8,CCDC85A,ESYT2,CASKIN1,SORCS2,TXNDC16,CC2D2A,C1QTNF3,ZNF687,PITPNM2,NT5C3B,FAM131A,CDC14B,SEMA4G,ARHGDIA,ARHGDIG,CHID1,N4BP2L1,KIF1A,DOCK11,CARMIL3,LDHD,JAZF1,CA12,KALRN,METTL6,SYNGR3,MAGI1,UBE2L6,DIS3L,CHN1,CHN2,EPS15L1,FBXO7,QKI,CCDC151,ARMC8,LETMD1,FAM171B,CLIP3,SIPA1L1,RASGEF1C,APPL1,GAPVD1,ARHGAP24,TBC1D5,LIN54,KIAA0586,INTS1,MAML1,ARMCX2,YTHDC1,ZNF804A,KIAA0753,SV2B,EXOG,NYAP1,RPS6KL1,FCF1,KLHL5,EBI3,MBNL2,C3orf18,TMEM35A,STARD3NL,CD320,ARMCX1,CLVS1,FAM198B,CEP78,KAT8,MAD2L2,SCARA3,ATP5PD,IQCG,DCTN2,TMEM175,EFCAB2,WDR83,JKAMP,AK8,FAM49B,ST6GALNAC3,MSANTD4,SARAF,DENND2A,HIGD1B,KIAA1841,MMADHC,ZNF276,RNPS1,RAB30,KDM2B,PRUNE2,ADAP1,PRDM5,ZBTB49,RABL2A,RASSF8,FRMD3,NCKAP1L,ARHGAP36,ZDHHC15,LRRCC1,DISP2,SLC35G1,GATD1,HECTD2,LYPLAL1,KCTD6,BLOC1S2,HS6ST3,TBC1D25,ZFYVE21,XRN1,FAM216A,ZNF426,MINDY2,CEP41,GDPD1,GDPD2,QRICH1,CNTLN,SPDL1,TMEM260,ZIK1,RIPOR1,ZSCAN2,MARCH1,SUSD4,RADX,KHDRBS2,ERI2,GTDC1,PRIMA1,SLC25A36,ZFHX4,KLHDC8A,CYB561D1,CCDC25,ELP2,NEK11,GLDN,TCP11L1,EMID1,FAM161B,ST6GALNAC6,TRAPPC13,FAM192A,RMI1,DGLUCY,ZNF821,TRA2B,HSPA4L,PUF60,SH3BP2,KIF21A,FERMT1,FUZ,CHD9,SYBU,NUBPL,WDR37,FAM81A,PPP4R3A,EPN2,FAM214B,KBTBD4,MTERF2,CABCOCO1,PDZRN3,KDM4B,FAM219A,ZBTB43,LHPP,PBLD,POGZ,KLHL7,DNAJC9,COBL,EXOC7,PDLIM2,KIAA1107,TBCEL,IQCE,PHF24,PCDHB7,PCDHB6,VWCE,C18orf54,CDH22,MTMR14,NACC2,BHLHB9,ERCC6L2,RIMBP2,PPIL6,CA14,PDIA2,PLEKHH2,TBC1D15,LMF1,PCDH20,ZNF23,ZFP41,TCEAL7,ZBTB38,FSTL5,ZNF189,SPIRE1,INTS3,EMSY,CADM2,DNALI1,TMEM178A,PPP1R3F,FAM13C,UBE3B,PHTF2,FBXO36,SNX14" Pubmed 16959763 Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Pubmed 1.32E-21 2.30E-16 5.89E-18 7.45E-17 48 138 "KCTD16,KCNAB2,PPFIA3,MADD,MARK4,ATP2B2,ARHGEF7,CAMK2A,CAMK2B,CAMK2G,ARHGEF2,CLTC,HOMER3,ARHGEF6,MATR3,EVL,GSN,PADI2,IDH3B,ITPKA,KIF2A,MAP2,MAP6,MARK3,MBP,GIT1,MYO5A,NF1,PDE1B,PLEC,PPP3CA,PPP3CC,PRKACB,ROGDI,RASGRF2,SBF1,MYO18A,WDR37,CCDC88A,ERC1,SPTAN1,SYN1,SYN2,DMXL2,SIK3,TUBB2A,CLIP2,TUBA1A" Pubmed 24194600 "The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data." Pubmed 1.59E-21 2.76E-16 6.89E-18 8.72E-17 161 1050 "SYN3,ELFN2,ESYT2,LRFN2,SLC24A4,CASKIN1,HACE1,BBOX1,PKP4,PARG,CPNE5,AQP6,ARRB1,ARRB2,ATP1A3,STX16,ATP2A2,DOCK11,ADAM23,BACH1,ADGRB2,SYNJ1,JAZF1,CACNA1I,GPC2,IL33,CA4,CAST,HIP1R,RHBDL1,CCK,KRIT1,CERS5,USP2,SCARB1,ARHGAP33,CHN1,PPT2,ABCG2,TMEM184B,CNR1,COL4A5,COX4I1,HAPLN1,CRYM,ARHGEF10,SIPA1L1,CST3,GREB1,PPP6R2,GPSM1,BOC,SNPH,SPOCK2,AIF1L,DBN1,KIAA0753,KLHL3,RPS6KL1,NCALD,ADGRV1,CLVS1,ABCA8,PRAM1,SLC9B2,FGFR1,BAIAP2,HPCAL4,RGPD5,FOXO3,EVL,SEMA4D,DCTN2,CINP,KHDRBS3,NSG1,HHIPL1,SYT17,ALDH1L1,GHR,DBF4,TOX3,GNAO1,TDRKH,TPPP,PARD3B,BVES,RABL2A,RASSF8,PADI2,PACSIN2,GABARAPL2,IL6R,IL6ST,LIFR,NCOA7,LSS,LYPLAL1,MAT2A,ADAM11,NEFH,NRCAM,NTRK2,IGSF11,OXTR,P2RX7,PCSK5,PDE1B,TMOD2,PFKFB4,KCTD15,PLCB2,PCDH18,PRIMPOL,MAPKAP1,STRN3,MBOAT7,EPB41L4B,PRKAB2,PKIA,FITM2,PRODH,NDUFS7,VPS13C,SH3TC2,IQSEC3,ENOX1,RDX,CARF,GSTCD,SNX22,NEK11,PEX26,DHX30,MAPKBP1,ZHX3,SPP1,TSPYL2,THSD1,SST,RHBDL3,DNAJC9,WSCD1,TPCN2,USP22,DICER1,AP4E1,ARL10,PARD3,ZNF346,SSBP2,TST,LGI4,NDRG4,LYPD6,ZNF142,FTSJ1,ADAMTS9,PARP11,FZD3,IFT88" Pubmed 17474147 Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Pubmed 9.78E-21 1.70E-15 4.15E-17 5.24E-16 76 330 "ABR,NCKAP5,BIN1,ANK2,SEMA7A,MAP4K3,PPFIA4,PPFIA3,SHROOM2,PRX,RGS20,CHRD,HCN2,SYNJ2,CAST,NFS1,LRBA,DLGAP2,DLGAP1,CNTFR,AKAP6,MYRIP,CSF2RA,RIMS2,DNM1,CELSR3,SEC24B,POLR1B,FOXF2,FLNC,AFF2,NBEA,FYB1,FYN,GABBR1,GABRA3,GAD1,ZNF274,CSDC2,GHR,GRB10,GRIN2D,MAP4K5,NXPH3,JAK2,KCNN1,MAP4,MIA2,P2RX7,PIK3R1,PKD1,SH3KBP1,PPP3CA,PTPRN2,DUSP15,ZKSCAN3,SMARCC2,SMARCD3,KIF13A,NFASC,ZC4H2,VPS13A,TAL1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMPO,TP53BP2,PDIA2,WIPF1,ZNF32,WNK2,RTN4" Pubmed 21516116 Next-generation sequencing to generate interactome datasets. Pubmed 1.03E-20 1.78E-15 4.24E-17 5.36E-16 169 1147 "SPOP,GPRASP2,OGT,EP400,CCDC146,PKP4,UPRT,RGS20,ZNF599,BMP7,AP1M1,CALM1,PTBP2,RUNX1T1,CBS,CCNH,CBFA2T2,ZBED1,CFL2,SRSF11,CHN1,FAM189A2,QKI,HOMER3,FHL5,AKAP7,MAGED1,HINFP,CRYBB1,TRIM69,PDE4DIP,DZIP3,MYADM,TCAF1,RIPOR2,DCAF8,MATR3,ARMCX2,FBXL5,POM121,PARD6A,SPOCK3,RAB39B,DPYSL2,DTNB,FIS1,E2F6,PHC2,HEYL,EEF1D,OPTN,YAF2,APH1A,DCTN4,NCALD,SH3YL1,FGF12,BAIAP2,AMOTL2,SCARA3,HPCAL4,SEC23B,IP6K2,VTI1B,HVCN1,SDCBP2,ZMAT1,TRAF3IP2,GAD1,MTHFD2,ZNF559,SEPT9,RUNDC3A,ZNF276,STARD3,RAB40B,FERMT2,LNX1,PRRC2B,CACFD1,GSTM5,GABARAPL2,ITPKB,METTL21A,KIF2A,KIFC3,KPNA5,LMO2,PIK3AP1,MAT2A,MIA2,SCAMP5,MID1,THYN1,HNRNPM,NCF2,NFYA,PDE4D,ZNF426,NECAB2,FA2H,SH3KBP1,C19orf57,PPP3CA,KANSL1,PRKAB2,MAPK7,MAPK9,CYBC1,PSMA6,PTPRN,C1orf109,PPP2R3C,RAD51D,RAP1GDS1,BEND5,RADX,KHDRBS2,RFX2,RFX3,RGS3,S100B,SCP2,PUF60,SHMT2,FAM214B,SEPHS1,NAPB,ABTB1,RCOR3,FAM126B,ZHX3,SP2,PEG10,ARHGAP26,ZC4H2,NXT2,MMS19,TACC1,TAF9,NEU4,TRIM2,TCF12,SLC19A3,SIK3,CYB561A3,THRA,CBX5,FAM124A,TPM1,WBP2,RUSC1,SSBP2,RPRM,EIF4ENIF1,MGAT5B,TBC1D15,WIPF1,ZNF23,ZNF24,MKRN3,TFIP11,PRTFDC1,SLC38A1,CIAPIN1,PLSCR4,RTN4,MSRB3,FRMD6" Pubmed 24722188 Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Pubmed 1.32E-20 2.30E-15 5.35E-17 6.76E-16 85 400 "DGCR6,GALNT13,ADORA2A,PTCHD1,ADRB2,CEP126,PCDH10,GPRASP2,DOC2A,LCORL,CASK,ARNTL,RGS20,KIF1A,NRP2,CACNA1G,CAMK2B,ZBED1,LARGE1,DLGAP2,RCBTB2,TAOK2,MAGED1,RCHY1,CRMP1,PDE4DIP,CNTNAP2,ZC3H11A,DLX1,DMPK,DPYSL2,SEZ6L2,ERBB2,FGFR3,GABRB3,DISC1,CPLX1,TUBGCP4,LNX1,INPP1,KIFC3,MARK1,MEIS2,MIA2,NTRK3,OXTR,PCDH9,PDE4B,NLGN3,NECAB2,PRKAB2,MAPK3,PRODH,MTMR10,RAP1GDS1,BEND5,CCDC102B,RPS6KA2,NUBPL,SLC6A8,NAPB,GKAP1,SNRPN,SP4,ZC4H2,CEP68,STX1A,IQCE,TCF4,TCF12,TNS2,TP53BP2,TSC1,TSC2,EIF4ENIF1,UBE2H,UBE3A,MGAT5B,CCDC136,VIPR2,AGMO,MKRN3,TFIP11,DOCK8,ST7" Pubmed 16512683 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. Pubmed 1.59E-20 2.77E-15 6.29E-17 7.95E-16 50 157 "ADD1,ADD2,AMPH,BIN1,VAT1L,BCAS1,PPFIA3,SPTBN4,ADGRB1,FUBP1,CALM1,CAMK2A,CAMK2B,DCLK1,CLTB,NGEF,MATR3,DYNC1I1,DPYSL2,PHF20L1,EPB41L2,MAP2,MAP6,MBP,NF1,PDE1B,STRN3,SEPT4,PPP3CA,DIRAS2,PTPRE,ROGDI,RPS20,SARS,SBF1,KIF21A,WDR37,SIRT2,NAPB,FNBP1,SPTAN1,CLASP2,SEPT8,SEPT3,STXBP1,SYN1,SYN2,SYT1,SYT5,RTN4" Pubmed 10817752 "Cadherin superfamily genes: functions, genomic organization, and neurologic diversity." Pubmed 3.09E-20 5.37E-15 1.19E-16 1.51E-15 34 74 "PCDH10,PCDHGB4,PCDH17,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 10716726 Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Pubmed 6.33E-20 1.10E-14 2.39E-16 3.03E-15 35 80 "PCDH10,PCDHGB4,CELSR3,PCDH17,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 17043677 Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Pubmed 1.01E-19 1.75E-14 3.72E-16 4.70E-15 48 151 "SPARCL1,GPRASP2,ANK2,DST,KALRN,AKAP6,NCOR2,PDE4DIP,KIAA0408,MATR3,DCTN1,TIAM2,SNAP91,DMD,DPYSL2,OLFM1,DCTN2,NBEA,SMC2,CAMKK2,DISC1,KIF5A,IPO5,SFR1,NEFM,PDE4B,CCSER2,KANSL1,PPP5C,ROGDI,PPM1E,CNKSR2,SYBU,CDK5RAP3,CCDC88A,SPTAN1,EXOC7,AGTPBP1,TRIM2,SYNE1,FRYL,TRIO,TUBB2A,CCDC136,CCDC14,ZNF17,TRIM9,TFIP11" Pubmed 10835267 Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. Pubmed 1.49E-19 2.59E-14 5.39E-16 6.82E-15 34 77 "PCDH10,PCDHGB4,PCDH17,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 20059953 A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Pubmed 1.52E-18 2.65E-13 5.40E-15 6.83E-14 188 1398 "MTA3,ZNF687,LCORL,PHF12,ARNTL,BACH1,BARD1,FUBP1,JAZF1,RUNX1T1,LDB2,CERS5,CCNH,CCNT1,CHGB,CNOT8,LHX2,VAX2,FHL5,MAGED1,TBPL1,ZNF521,ZFP28,ZNF385A,FAM171B,RBM39,RNF14,HINFP,NCOR2,SNCAIP,PPP1R16B,PHF14,PYGO1,MAML1,ZBTB24,MYEF2,B3GAT3,NR1D2,DMTF1,E2F5,E2F6,EBF1,ANKRD46,FEM1B,HEYL,EGR3,ASB3,ING4,EMX2,ERCC2,ETV1,EZH1,KAT8,PPP1R1B,POLR1B,FHL1,FOXF2,FOXO3,NELFCD,ZMAT1,ZNF274,CSDC2,PPARGC1A,BRD8,ZNF276,TCERG1,GLI2,TOX3,MSL3,HTATSF1,PRRC2B,STON1,TMEM121B,PRDM5,KAT7,PSIP1,ATOH8,MIER3,HLF,HNF4G,ZDHHC15,HSF2,IRF8,IFI16,ZNF546,RBPJ,LMO2,SMAD1,MEF2C,MEIS2,MID1,MITF,MXI1,MYCN,NACA,NFE2L2,NFIX,NFYA,CNOT4,CHAMP1,PAX6,ENPP2,DUSP26,ZNF655,ZNF426,ING3,POLR2F,POU6F1,IRX1,PPARA,TMEM260,ZIK1,ZSCAN2,DPF2,RFX2,RFX3,UBR7,PBRM1,CARF,RORB,ARMH4,FBXW7,KCNIP3,ZNF354C,RXRA,SATB1,HES6,ZFP2,ZFP30,ARX,ANKRD6,PKNOX2,SIRT2,ATF7IP,ZKSCAN3,ZFP1,ZNF667,ABTB1,SMARCA4,KDM4B,TRERF1,SOX15,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,KANK1,SUPT5H,MMS19,TAF6,TAF9,TAL1,TCEA1,TCF4,SIN3B,ZFP90,TCF12,CRTC1,SIRT1,ZFPM2,THRA,HEY1,NR2E1,TMPO,TP53BP1,TRPS1,SSBP2,ZKSCAN5,UBTF,VAV1,CLIP2,ZFP37,ZBTB14,ZIC1,ZIC2,ZNF23,ZNF24,ZNF32,ZFP41,ZBTB38,POLR3H,ZNF189,MEIS3,MAP3K12,JMJD1C,DPF3" Pubmed 21145461 Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Pubmed 2.19E-18 3.81E-13 7.61E-15 9.63E-14 216 1696 "ABCF1,ACADM,TMCC3,GALNT13,BRAP,KLHL13,AK2,SMIM17,SRPX,GPRASP2,LRCH2,CCDC146,TNRC6C,ARHGDIA,ZBTB10,CCAR2,DYNLL1,ATP1A1,ATP2A2,BCL7A,BLM,LDHD,FUBP1,NAE1,MTMR3,CALM1,CAMK2G,CBR1,ARHGEF1,SCARB1,ZMYM4,CCPG1,SRSF11,SOCS6,MYL6B,CLTC,FBXO7,ARMC8,MAGED1,BAG4,RBM39,SEC24C,SOCS5,PUM1,GPSM1,DCAF4,DCAF8,MATR3,DCTN1,FBXL5,DDX46,RHOBTB1,SEC16A,NYAP1,DYNC1I1,PDCD6IP,DNAJB6,DNM1L,FEM1B,EEF1D,KLHL5,YAF2,ASB3,KCTD3,EIF4G1,EIF4G2,COPS4,SRPK3,ENO2,SRRM1,MRPL37,TUBB3,RACK1,PRMT5,FECH,SEC24B,POLR1B,AMOTL2,SEC23B,SYNCRIP,FLNC,ANKFY1,NOP56,DCTN2,STAU2,FAM120B,MTHFD2,COPS8,RNPS1,TNRC6A,ZNF638,HTATSF1,POLL,RAB40B,GPT2,CCDC184,PTPRT,MUM1,NXPH3,MAN1B1,DDX19B,ATXN2L,BACH2,HMGCR,HSPA1L,KNDC1,KCNH2,KLHL23,KHK,KPNA5,IPO5,ASPRV1,MAP4,MAT2A,LRP1B,KCTD6,MOV10,MPP2,DBNL,PTOV1,MYH3,NACA,HNRNPM,KSR2,NUCB2,OPA1,FAM98B,PIK3R1,PKM,NLE1,PLEC,SLC25A23,EXOSC10,PRKAR1B,PRPH,PRPSAP2,DCHS2,MASP1,RELN,PSMA6,ANKHD1,QDPR,FAM184A,RBBP6,DPF2,FIGN,RGS12,KCTD17,KLHL11,DCUN1D2,ARMC5,PCMTD2,RPL15,FBXW7,MCMBP,RPS20,HSD11B1L,RYR3,NCBP3,SAFB,ATXN2,CASC3,TRA2B,PUF60,MYO18A,SHMT2,AMBRA1,FBXO11,SEC31A,SLA,DHX30,KDM4D,SEPHS1,KBTBD4,BTBD7,COA1,ABTB1,SMARCA4,SMARCC2,ZSWIM8,MYCBP2,ERC1,SPTAN1,TROVE2,ZNF302,LARP4,SS18,STAU1,TTBK2,KLHL7,SUPT5H,ADAMTS17,DNAJC9,MMS19,ANKRD12,FBXW11,KLHL4,DOCK9,PCDHA6,DICER1,ZNF346,TUBB2A,TUBB1,UBC,RPL7L1,TBC1D15,TRIM9,FTSJ1,PRDM10,TUBA1A,FIP1L1,HNRNPA3,FXR1,SOCS4,GAN,LAS1L" Pubmed 29031500 Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Pubmed 6.12E-18 1.06E-12 2.09E-14 2.64E-13 60 246 "SEMA6A,ALK,SEMA4G,ARNTL,NRP2,BMP7,JAZF1,CALB1,SLIT2,SLITRK5,DLX1,EBF1,EDN1,EDN3,EDNRB,SEMA3D,CELSR3,ETV1,FGF1,FGF13,FGFR1,FOXO3,SEMA4D,CSPG5,GFRA2,HLF,IGF1,L1CAM,MEF2C,MEIS2,MYCN,MYT1,NPY,NRCAM,NTRK2,NTRK3,PLXNB1,PTCH1,PTN,ZIK1,PTPRN,PTPRO,RET,ZFHX4,ROBO2,RXRA,SEMA6D,SATB1,SOX11,ZHX3,TCF4,SATB2,CUX2,ZEB1,TCF12,FLRT2,ZNF24,ZNF184,SEMA3B,FZD3" Pubmed 26673895 A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Pubmed 9.77E-18 1.70E-12 3.27E-14 4.13E-13 150 1038 "ABCF1,ADD1,AP2A1,TBC1D14,BEGAIN,PITPNM2,TNRC6C,MADD,ARRB2,PDE8B,NUMB,CCAR2,RIPK1,BACH1,KSR1,AP1M1,IL33,CFAP410,ARHGEF1,AP4M1,SEPT7,CDC25B,EVI5L,NUMBL,DIS3L,COPB2,EPS15L1,MAP4K4,CRY2,SEC24C,CSNK1E,PUM1,PPP6R2,GPSM1,GAPVD1,DCAF8,TBC1D5,MAML1,SPATA2,RUSC2,WDR20,SEC16A,DMD,MED12,TOM1,DNAJB6,KCTD3,EIF4G2,EIF5,PAN3,ERCC2,TUBA1B,TUBB3,CEP78,STRADA,SEC24B,AMOTL2,SEC23B,FOXO3,EVL,CINP,ZBED3,PDLIM5,AP4B1,RAPGEF6,SEPT9,WASHC2A,MALT1,RNPS1,DBF4,FERMT2,GRB10,CLASRP,KAT7,AGFG1,DHX35,SMAP1,RBPJ,KNDC1,TJAP1,LSS,SMAD1,MITF,HNRNPM,NEK1,CNOT4,OCRL,PDE4B,PDPK1,FAM98B,XRN1,MAPKAP1,STRN3,SCHIP1,PPM1B,PRKACB,CEP41,PRKAR1B,MAPK7,BCAS3,SNRK,C1orf109,RIPOR1,CEP97,USP47,ROGDI,RIC8B,GSTCD,SARS,CASC3,COPZ1,SH3BP2,FERMT1,SEC31A,SIRT2,CCDC88A,BTBD7,ARFGAP1,LIMCH1,ZSWIM8,IQSEC2,RBM26,CLASP2,POGZ,ERBIN,NEK4,SEPT8,PHLDB1,PJA1,MLST8,AGTPBP1,TBL1X,TCF12,CLASP1,CRTC1,AP4E1,MTMR14,R3HDM1,EIF4ENIF1,GORASP1,TOM1L2,TBC1D15,RICTOR,XPO1,UPF3A,FIP1L1,ACTR3B,AAAS,RNF146,LAS1L" Pubmed 10380929 A striking organization of a large family of human neural cadherin-like cell adhesion genes. Pubmed 1.45E-17 2.51E-12 4.74E-14 6.00E-13 31 72 "PCDH10,PCDHGB4,CELSR3,PCDHGC3,PCDH8,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 15345747 Phosphoproteomic analysis of the developing mouse brain. Pubmed 1.83E-17 3.18E-12 5.90E-14 7.46E-13 58 237 "ABCF1,ADD1,ADD2,AMPH,APBA2,CCAR2,PTBP2,DCLK1,DLGAP1,MAP4K4,PCYT1B,AKAP12,CRMP1,APPL1,PPP6R2,GPSM1,DBN1,SNAP91,PARD6A,TMCC2,SRRM1,DCTN2,OGA,HTATSF1,GRB10,KIF2A,MAP2,MAP4,MAPT,SAMD14,NACA,HNRNPM,SFR1,NEK1,PALM,PDE1B,KCTD15,CEP41,USP47,FAT4,NUDT11,CCDC25,RPS6KA2,CLIP1,CNKSR2,SYBU,EPN2,SMARCC2,TMCC1,SOX11,CLASP2,SYN1,COBL,EIF4ENIF1,TBC1D15,REEP1,TUBA1A,RTN4" Pubmed 11230163 Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Pubmed 2.08E-17 3.62E-12 6.57E-14 8.31E-13 30 68 "PCDH10,PCDHGB4,PCDHGC3,PCDH8,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 27880917 Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Pubmed 5.37E-17 9.33E-12 1.67E-13 2.11E-12 149 1048 "RALGAPA1,ADD2,USP31,ESYT2,MTUS1,AK2,CDC42BPA,PKP4,PPFIA3,CDC14B,PPP4R4,MADD,CASK,NUMB,CCAR2,STX16,ATP2A2,BLM,MTMR3,MTMR2,WASF1,SPAG9,CCNH,MTMR7,ARHGEF2,CDC25B,NUMBL,COPB2,CBARP,CLTB,CLTC,AKAP5,COX4I1,FAM171B,CDC42BPB,NCOR1,NCOR2,PUM1,PPP6R2,ARHGAP32,ZFYVE16,TBC1D5,DAPK3,DBT,KIAA0753,WDR20,SEC16A,DMD,ACOT8,RCAN1,DTNA,DTNB,DUSP9,CNNM1,EGFR,KCTD3,PLEKHA1,EYA1,ACSL4,TUBA1B,FDFT1,FECH,SEC24B,BAIAP2,ATP5PD,NBEA,CSPG5,NEURL4,GLYR1,TNRC6A,ZNF638,PRRC2B,GPD2,PTPRT,SCIN,C2CD4C,PPM1L,MYO5A,OPA1,PALM,DUSP26,PIK3R1,PSAT1,PPM1B,PPP2R5E,PPP3CA,PPP3CC,PPP5C,MAPK3,MAPK9,MTMR10,PTPN13,PTPRB,PTPRD,PTPRE,PTPRG,PTPRH,PTPRN,PTPRN2,KIF7,ROBO1,KIRREL1,ELP2,FBXW7,MCMBP,SBF1,ATXN2,PPM1E,SHMT2,PPP4R3A,CCDC88A,SLC12A2,SLC12A4,CDK5RAP2,MYCBP2,ERC1,SPTAN1,CLASP2,ITPRID2,ERBIN,SUPT5H,SYNE2,VPS13A,ANKRD28,AGTPBP1,FBXW11,RPGRIP1L,TNS2,GPRIN3,TIAM1,MTMR14,TMPO,TNS1,TP53BP2,ELP5,TRIO,STXBP4,TRPS1,TSC1,TUBB2A,UBTF,USP1,CCDC14,RICTOR,XPO1,SLC38A1,ST7,NHSL1,AAAS" Pubmed 15146197 Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Pubmed 1.56E-16 2.72E-11 4.77E-13 6.03E-12 153 1101 "GALNT13,ADD2,ADORA2A,PWWP2A,FAHD2CP,ZNF608,HACE1,USP35,ANK2,NT5C3B,ARSE,EIF4G3,ATP1B3,ADAM23,BID,FUBP1,DDR1,CBLN1,CBFA2T2,ARHGEF2,CDH2,SRSF11,TAOK2,CLTB,HOMER3,CNN3,COX4I1,CPS1,CREM,ENTPD4,NCOR2,ARHGEF10,CSNK1G3,VCAN,PUM1,RIMS2,RUBCN,MYADM,KATNAL2,KIAA0586,DAPK1,ARMCX2,HEPH,RHOBTB1,ABCC5,E2F5,EEF1D,TENM1,PLEKHA1,TNK2,MRNIP,MFSD10,STX2,ERBB2,ERCC2,ZNF391,ETV1,TBC1D16,ACSL4,TMEM164,UBE2E3,IP6K2,SLC37A3,NOP56,FLYWCH1,SPECC1,UFM1,FAM49B,TVP23A,ZNF44,NEU3,ARFIP1,WASHC2A,AHDC1,FREM1,PRRC2B,TMEM121B,DIDO1,LINC01089,MAP4K5,ZHX1,PACSIN2,BACH2,HMGCR,HNRNPUL2-BSCL2,ZIC5,IBA57,KIT,LAMA2,LMO2,SMAD9,ADAM11,MEST,BLOC1S2,SAMD14,HNRNPM,NF1,NNAT,NOVA1,CHAMP1,OPA1,OPRL1,PALM,PDE4B,PKD1,KCTD15,PRODH,CYBC1,PTN,RIPOR1,TUG1,ZDHHC4,RPE,MCMBP,LRRK2,CCDC112,AP1AR,SAFB,MRAS,PUF60,SHMT2,RADIL,EPC1,ZNF415,MYCBP2,ZNF423,ZC3H13,DBNDD2,SPTB,APOM,ZC3H4,VPS13A,ANKRD28,MMS19,AGTPBP1,MGRN1,NSD1,C18orf54,ITGB3BP,ANKRD24,TPM1,RUSC1,TTC3,TMEM161B-AS1,BCL2L13,CCDC14,KLC2,ZNF28,ZNF154,EVI5,RTN4,ADAMTS10,RNF146" Pubmed 19322201 Ubiquitin-mediated proteolysis of HuR by heat shock. Pubmed 2.36E-16 4.10E-11 7.07E-13 8.93E-12 207 1671 "NDRG3,RNF150,ADRA1D,MTA3,BIN1,APAF1,FAM131A,CASK,ATP2A2,RNF182,ADAM23,BARD1,FUBP1,MTMR2,CALM1,PTBP2,CAST,SLC16A4,ARHGEF2,SEPT7,FOXN3,CNOT8,QKI,COL4A5,SUMF2,TBPL1,BAG4,ZNF521,CPS1,PREPL,C2CD2,ABCG1,CSNK1E,OSBPL3,CSNK1G3,PDE4DIP,APPL1,CTH,PUM1,MYADM,GAPVD1,HDAC4,CENPL,TM9SF4,LIN54,AIF1L,SPATA2,ELMSAN1,KLHL3,DDX46,GUCD1,FAM107B,USP3,DPYSL2,PDCD6IP,GOLT1B,ANKRD46,APH1A,MBNL2,ASB3,PLEKHA1,STARD3NL,PAN3,SLC43A2,STX2,SRRM1,KATNAL1,ACSL4,TUBB3,FECH,PRKAG2,FOXO3,SEMA4D,FLYWCH1,ZBED3,UFM1,FAM49B,ATP2C1,CELF1,STAU2,OGA,ZNF234,MTHFD2,RNPS1,SPIN1,GLYR1,ZNF638,GRB10,CIT,RABL2A,MAP4K5,MUM1,ZHX1,ELOVL5,GABARAPL2,HP,RBPJ,TJAP1,ITPKB,SLC35G1,LAMP2,HECTD2,MAT2A,MID1,MITF,MKLN1,GIT1,CNOT4,NPTX1,SMIM11A,OCRL,OPA1,PCDH9,PFKFB3,SNX10,SLC25A23,SMIM7,ZNF426,PMP22,STRN3,ING3,EPB41L4B,SH3KBP1,DRAM2,IRX1,PPP2R5E,PTK2,ZDHHC14,RDX,DUSP15,ZNF532,C12orf49,CCDC25,SPIN3,FAM192A,AP1AR,SAFB,SCP2,CASC3,SGK1,KIF21A,FBXO11,FNDC3A,R3HDM2,CCDC92,PEX26,BTBD3,SEPHS1,SLC9A5,NAPB,SMARCC2,RCOR3,LIMCH1,USP33,TRERF1,FNBP1,IQSEC2,ZBTB43,SSTR2,LARP4,SS18,NXT2,STAU1,PRRC2C,FAM208A,TBL1X,MGRN1,SATB2,TRIM2,TCF12,CLASP1,PUM2,SIK3,SIRT1,DICER1-AS1,C18orf54,AP4E1,ZMAT3,SLC44A1,HEY1,LRRC8A,TPM1,NEIL2,HIRA,UBC,RPRM,UBE2H,OSBP2,CCDC14,WIPF1,RICTOR,XPO1,ZBTB14,ZIC2,REEP1,DHX33,INTS3,MAP3K12,EVI5,KCNAB1,PDSS2,KAT6A,PHTF2,FAM219B,RSPRY1,FXR1,NETO2" Pubmed 16284245 Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Pubmed 2.93E-16 5.10E-11 8.64E-13 1.09E-11 39 123 "UNC5A,SEMA6A,SEMA7A,SEMA4G,PTCH2,CALB1,CALB2,LDB2,SLIT2,LHX2,CRYM,PLXNA4,BOC,CDON,SEMA3D,PLXNC1,EMX2,ETV1,FGFR1,FGFR3,SEMA4D,GAD1,NTNG2,KITLG,NEFH,PAX6,SEMA5B,RELN,PTCH1,PTN,ROBO1,ROBO2,RORB,SEMA6D,UNC5B,CDH22,SEMA3B,NETO2,NETO1" Pubmed 10048485 Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 3.01E-16 5.24E-11 8.73E-13 1.10E-11 35 100 "RALGAPA1,AP2A2,ADGRF5,PPFIA4,SYNJ1,TAOK2,CNTNAP2,FAM169A,SLITRK5,PPP1R16B,FAM13A,ABCA8,PCYOX1,USP19,MYT1,NEFH,CNKSR2,SEC31A,ABLIM3,DHX30,WDR47,MYO16,KDM4B,ZSWIM8,MYCBP2,ZC3H13,MCF2L2,CAMTA2,MPRIP,TTBK2,ANKRD12,CAMTA1,DMXL2,FRYL,RTN4" Pubmed 14691545 Transcriptome analysis of mouse stem cells and early embryos. Pubmed 4.97E-16 8.64E-11 1.42E-12 1.79E-11 61 276 "NCKAP5,TAOK1,CDC14B,DOCK11,CACNA1G,CAPN3,LDB2,CCPG1,CNTN1,COL4A5,LETMD1,HINFP,LRIG1,PDE4DIP,ERC2,PUM1,DCAF4,ARHGAP32,SNAP91,FARSB,EDNRA,EIF4G2,POLK,STAU2,ZNF274,USP19,FERMT2,GSN,RBPJ,ITGA7,IPO5,MBNL1,TM6SF1,PLEC,EPB41L4B,BCAS3,CYBC1,DEF8,MTMR10,RAP1GDS1,PBRM1,NCBP3,ZNF821,SGK1,KIF16B,FBXO11,SLC12A2,OGDHL,USP33,LARP4,RGL1,ZC3H4,PJA1,DOCK9,ZNF106,NACC2,TMPO,CABIN1,P2RY12,ZIC1,ADAMTS9" Pubmed 24255178 Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Pubmed 5.34E-16 9.29E-11 1.50E-12 1.89E-11 82 446 "RALGAPA1,AP2A1,AP2A2,AMPD2,LRCH2,PKP4,APC,DYNLL1,DOCK11,MPDZ,KSR1,DST,MTMR3,ARHGEF2,MAGI1,HECTD1,MAP4K4,MAGED1,ANKRD44,CSNK1E,SIPA1L1,PUM1,PPP6R2,GAPVD1,HDAC4,RASSF2,TBC1D5,DBN1,KIAA0753,SEC16A,PLEKHA1,DENND4A,BAIAP2,AMOTL2,AGAP3,FOXO3,RAPGEF6,TNRC6A,RASSF8,KIF2A,MARK1,MARK3,AFDN,NF1,CDK18,PDCD2,PFKFB2,PIK3C2A,CCSER2,STRN3,PTPN13,DPF2,KIF7,KIRREL1,CLIP1,R3HDM2,RADIL,CPEB4,UHRF1BP1L,ERC1,SPTAN1,CLASP2,NEK4,ANKRD28,MTCL1,KIAA0930,CLASP1,FRYL,R3HDM1,PARD3,TP53BP2,TPM1,WBP2,RUNDC3B,STXBP4,TSC2,TUBB2A,EIF4ENIF1,KLC2,RICTOR,SH3GLB2,DOCK8" Pubmed 20201926 Human variation in alcohol response is influenced by variation in neuronal signaling genes. Pubmed 8.02E-16 1.39E-10 2.20E-12 2.79E-11 46 171 "ADRB2,DDO,ASPA,BMPR1B,LARGE1,CHRNA4,ENTPD4,VCAN,ERC2,DYNC1I1,DOCK2,GAD1,CPLX1,GLI2,ZNF638,PCLO,GRIK4,ADAMTS13,GRM8,PTPRT,HLF,SYNPO,IRF8,MATN3,MYO6,MYO7A,NEFM,PDE4B,PDE4D,PKD1,PTPRB,PTPRD,PTPRE,PTPRG,PTPRN2,QDPR,ROBO2,RORB,RYR3,NLGN1,CDK5RAP2,MYO16,ERC1,DICER1,PDSS1,TSC2" Pubmed 23055939 A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. Pubmed 8.11E-16 1.41E-10 2.20E-12 2.79E-11 31 81 "ADD1,WDR35,MADD,CASK,CADPS,DYNLL1,SYNJ1,CACNA1B,PTBP2,CHGB,ERC2,RIMS2,SNAP91,DTNA,ATP13A4,ERGIC3,RAPGEF6,SRRM4,CIT,FAM222A,MYO7A,NRCAM,VPS13C,STUM,NUBPL,KANSL3,SNAP25,DOP1A,CLASP2,MCF2L,SNX14" Pubmed 10718198 Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.24E-15 2.15E-10 3.31E-12 4.19E-11 43 153 "HECW2,KLHL13,CASKIN1,PCDH19,KCTD16,RTL9,HACE1,TBC1D14,KIAA1324,SORCS2,WDR35,TXNDC16,CC2D2A,TAOK1,SEMA6A,USP35,CEP126,ARHGAP20,CARNS1,MARCH4,PCDH10,UNC79,FAM135A,SYT13,ZNF687,ZFP28,SH2B1,APPL1,INTS1,MYEF2,CASP8AP2,PDCD6IP,GPHN,SPEG,ATP2C1,VPS13C,KANSL3,RCOR3,LRRC8A,STOX2,ADAMTS9,JMJD1C,NHSL1" Pubmed 20412781 Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Pubmed 1.44E-15 2.51E-10 3.80E-12 4.80E-11 114 744 "KDM5D,MTA3,ZNF687,LCORL,ARNTL,NCOA1,BACH1,SCAPER,JAZF1,LDB2,CERS5,ZNF445,TBPL1,AHCTF1,ZFP28,ZNF385A,CLOCK,CREM,HINFP,NCOR1,PHF14,ZBTB24,NR1D2,DMTF1,E2F5,E2F6,EBF1,PHF20L1,MBNL2,PLXNC1,ING4,ETV1,FOXO3,ANKFY1,PDLIM5,ABLIM2,ZNF274,SRCAP,BRD8,DBF4,GLYR1,TOX3,ZNF638,DIDO1,PRDM5,ZNF496,KAT7,SOX21,BACH2,IRF8,ZIC5,RBPJ,LIMS1,SMAD1,MBD1,MBNL1,MEIS2,MYCN,MYT1,NFE2L2,NFYA,PAX6,ZNF655,ZNF426,ING3,PPARA,ROGDI,ZDHHC14,DPF2,RFX2,RFX3,ZDHHC4,PBRM1,ZNF354C,RXRA,SALL1,SATB1,HES6,DZIP1,LIMS2,ZNF334,BTBD7,ZKSCAN3,KDM4B,TRERF1,SOX3,SOX15,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,RBM26,POGZ,JMJD6,TAF6,TCEA1,TCF4,SATB2,CUX2,ZEB1,TCF12,ZMAT3,THRA,HEY1,NR2E1,ZNF346,TRPS1,UBTF,ZFP37,ZFP41,ZDHHC20,DPF3" Pubmed 12465718 Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 2.30E-15 3.99E-10 5.95E-12 7.53E-11 32 89 "TBC1D14,SORCS2,SYNJ1,ARHGEF2,DCLK1,ENTPD4,NCOR1,AATK,TM9SF4,SNAP91,EZH1,NBEA,PCLO,KCND2,MBNL1,MYT1,CPEB3,CHD9,BTBD3,ELMO2,ZSWIM8,UHRF1BP1L,CLASP2,ITPRID2,MPRIP,SEPT8,DIP2A,SYNE2,FBXW11,PCDHGA2,FRYL,ZNF142" Pubmed 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 2.59E-15 4.50E-10 6.62E-12 8.36E-11 63 301 "ACHE,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,CCK,NRXN3,CNR1,PICK1,CNTFR,CNTN1,NRG2,CRHBP,CNTNAP2,DBI,SNAP91,GRIN3A,EGFR,PPP1R1B,NBEA,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,DISC1,GRIA2,PLCD4,GRIK4,GRIK5,GRM2,INPP1,L1CAM,NCAM2,NPY,NPR2,NRCAM,NTRK2,NTRK3,OXTR,CNTN3,ABCB1,PLCD1,RELN,PTN,S100B,SHMT2,NLGN1,SLC6A11,SNAP25,SST,SSTR1,SSTR2,SYN1,ASTN2,TACR1,TSC2,UBE3A,VIPR2,TFIP11,SLC17A7" Pubmed 9371744 Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Pubmed 3.40E-15 5.91E-10 8.57E-12 1.08E-10 50 205 "ABR,AGT,SPARCL1,LDHD,CBLN1,DLGAP1,NGEF,CNTN1,MAGED1,COX4I1,ZFP28,CRMP1,RNF14,LRIG1,PDE4DIP,CST3,RIMS2,TMEM170A,PLPPR4,SPEG,TUBA1B,RACK1,GP1BB,GPR12,KIF5A,MBP,MPP2,NPTX1,PKM,PRKAR1B,MAPK3,SNRK,PTK2,SGSM1,SARS,CCDC92,TTC17,SNRPN,UNC5B,DBNDD2,TSPYL2,DDN,SYN2,TCF12,TUBB2A,UBE2H,NDRG4,TUBA1A,RGS7BP,NHSL1" Pubmed 12975309 "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Pubmed 6.89E-15 1.20E-09 1.71E-11 2.16E-10 137 987 "KIAA1324,C1QTNF1,C1QTNF3,C6orf89,PI16,FAM131A,PTCH2,CHRD,TMEM108,ST3GAL5,SGCE,SLC25A14,CRLF1,TAOK2,NDST3,PPT2,TPP1,FAM19A5,SUMF2,LRRC3B,PLXNA4,BOC,MYADM,INTS1,SPOCK2,AIF1L,HEPH,TMEM130,LYPD1,SPOCK3,TMCC2,HS3ST2,CD99L2,TOM1,GOLT1B,SEZ6L2,SEMA3D,EEF1D,APH1A,PCOLCE2,STARD3NL,PAN3,HSD17B14,LRRC17,ENPP6,TLR7,CD320,FAM198B,PCYOX1,ATP13A4,TMEM107,HVCN1,ST6GALNAC3,SARAF,HHIPL1,MEGF11,GALNT15,ERAP1,LYVE1,DHRS4,NTNG2,LUZP2,LNX1,ADGRA3,ADAMTS13,CACFD1,CLASRP,COQ10A,FICD,LINGO1,RNFT2,NXPH3,MAN1B1,VSIG4,ZDHHC15,NEGR1,LRRC25,LRRTM1,ITGA7,CLEC18A,MATN2,PTOV1,LAYN,DNHD1,IGSF11,CYTL1,SEMA5B,SMOX,TRHDE,DRAM2,LRRN3,GRAMD1C,GDPD2,PIGG,TMEM231,SUSD4,ZDHHC4,KIF7,GLDN,STK32B,ST6GALNAC6,DGLUCY,SCN2B,TNFRSF19,SHC4,LGI3,ANKRD36,GLT8D1,IZUMO4,UNC5B,THSD1,SULF2,ALG1,PCDHB10,ENHO,TMEM9,RELL2,LRRC8A,FAM124A,CSMD1,CHST5,CA14,FLRT2,MTCH1,TOM1L2,TSPAN11,CLDND1,LGI4,LYPD6,GDPD5,TMEM178A,SIGLEC10,PLD4,RSPRY1,MSRB3,NETO2,ST8SIA2" Pubmed 10470851 Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 8.29E-15 1.44E-09 2.03E-11 2.57E-10 34 104 "MTMR2,NCOR1,ARHGEF4,SYNPO,KCND2,MYT1,ANKHD1,IQSEC3,PCMTD2,SCAF8,PPM1E,NLGN1,EPN2,LIMCH1,PDZRN3,USP33,DOP1A,ERC1,PEG10,CDK19,ZC3H4,PRRC2C,TACC1,EXOC7,FAM208A,KIAA1107,AGTPBP1,IQCE,SATB2,USP22,DOCK9,PHF24,TNS2,TRO" Pubmed 22558309 Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks. Pubmed 1.17E-14 2.03E-09 2.82E-11 3.56E-10 35 111 "AGT,LTBP4,AMPH,DST,SYNJ2,DLGAP2,DLGAP1,EPS15L1,CLTC,PDE4DIP,PDCD6IP,CEP85L,DISC1,AHDC1,AGFG1,GAREM2,ITPKA,PIK3AP1,MBNL1,PDE4D,PIK3R1,SH3KBP1,SPDL1,KIF16B,EPN2,FNBP1,ERC1,SYN1,TACC1,ZFPM2,TIAM1,NR2C2,TRIO,WIPF1,CLIP2" Pubmed 22939624 Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Pubmed 1.92E-14 3.33E-09 4.56E-11 5.77E-10 70 371 "KLHL32,KLHL13,ALK,CDK10,RIPK1,RGS11,KSR1,BTK,DDR1,CAMK2A,CAMK2B,CAMK2G,RCBTB2,SOCS6,MAP4K4,CSF1R,RGS6,CSNK1E,KCTD8,DAPK3,RHOBTB1,DMPK,RPS6KL1,EGFR,ASB3,TNK2,SRPK3,EPHB1,ERBB2,ERBB4,RPS6KC1,PTK2B,TAOK3,FER,GTF2IRD2,FGFR1,FGFR3,CAMKK2,FYN,DCLK2,LNX1,ZBTB49,IRAK3,MYLK2,KLHL23,MATK,NTRK2,NTRK3,KSR2,CDK18,PRKACB,PRKCB,MAPK4,MAPK7,PTK2,RET,ARMC5,NEK11,FBXW7,RPS6KA2,STK32B,SGK1,KBTBD4,FBXW11,TRIM2,NR2C2,SGK3,ZNF74,MAP3K12,GAN" Pubmed 9872452 Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 2.09E-14 3.63E-09 4.90E-11 6.20E-10 33 101 "ADGRF5,DST,BAIAP3,ZBED1,NRXN3,SLC4A8,PHF14,RIMS2,FAM131B,DOCK4,HDAC9,ARHGAP32,TCAF1,MATR3,DGKB,SPATA2,KIAA0753,DDX46,RHOBTB1,SACS,SV2B,CAMKK2,TMCC1,KDM3A,KDM4C,ZNF423,DDN,NFASC,ATP10B,MTCL1,ADGRL3,SMG6,SYNE1" Pubmed 15772651 The DNA sequence of the human X chromosome. Pubmed 2.25E-14 3.91E-09 5.21E-11 6.58E-10 74 406 "KLHL13,PCDH19,SRPX,GPRASP2,LRCH2,MAGEE2,UPRT,SHROOM2,BTK,SLC25A14,RGN,RAB33A,ARHGEF6,MAGED1,GPRASP1,PABPC5,ARMCX4,ARMCX2,CHRDL1,RAB39B,DMD,DUSP9,TENM1,TMEM35A,RAB9B,RRAGB,ARMCX1,TMEM164,FHL1,AFF2,HTATSF1,MAP7D2,LPAR4,ARHGAP36,ZDHHC15,USP51,TCEAL6,L1CAM,LAMP2,SYTL4,CHIC1,RTL5,NEXMIF,TCEAL5,BEX5,ZC3H12B,OCRL,SMIM10L2B,GDPD2,TMEM255A,RADX,MORC4,NUDT11,TMLHE,SPIN3,CNKSR2,DMRTC1,SOX3,IQSEC2,ZC4H2,NXT2,ARHGEF9,NUDT10,SYN1,PJA1,KLHL4,BEX4,TRO,ZNF711,TCEAL7,FTSJ1,ZXDA,WNK3,LAS1L" Pubmed 19554387 The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Pubmed 3.48E-14 6.04E-09 7.95E-11 1.01E-09 31 91 "ACHE,OGT,SEMA4G,CALB2,CABP7,KCNAB3,HOMER3,CNR1,WHRN,SPOCK3,RCAN2,NSG1,GAD1,GRM2,GRM8,RASSF8,SHISA6,LRRTM1,KIT,NEFH,SERPINI1,EML5,IQSEC3,ZMAT4,SNCA,SST,CDH22,VGF,VLDLR,TRIM9,LYPD6" Pubmed 10231032 Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 3.95E-14 6.88E-09 8.93E-11 1.13E-09 33 103 "MYRF,THSD7A,CAMK2A,TBRG4,CORO2B,AMOTL2,SEPT9,CIT,PADI2,ZFP30,FRMPD1,CPEB3,FNDC3A,R3HDM2,DZIP1,ANKRD6,WDR37,BTBD3,MAST1,MYH15,FAIM2,RGL1,SYNE2,VPS13A,DNAJC9,DNMBP,KIAA0930,RPGRIP1L,SIK3,DNAH7,DICER1,ZKSCAN5,NAV3" Pubmed 25056061 Biological insights from 108 schizophrenia-associated genetic loci. Pubmed 4.53E-14 7.87E-09 1.01E-10 1.28E-09 61 303 "ASPHD1,AS3MT,DOC2A,PITPNM2,ATP2A2,CA8,DGKI,TAOK2,CLCN3,NGEF,ANKRD44,RGS6,PPP1R16B,TBC1D5,ZNF804A,PARD6A,SGSM2,SEZ6L2,TMTC1,APH1A,REEP2,APOPT1,FUT9,LUZP2,KCNB1,TMEM110-MUSTN1,MAN2A2,MEF2C,MMP16,NEK1,ZFYVE21,PLCB2,PLCL1,MAPK3,CNNM2,WBP1L,PTN,ZSCAN2,C1orf54,MSANTD2,PBRM1,ATXN7,GALNT10,SHMT2,R3HDM2,CNKSR2,SLC12A4,TSNAXIP1,GLT8D1,NEK4,SEPT3,PJA1,SMG6,TCF4,SATB2,SLC35G2,CSMD1,CA14,TOM1L2,ADAMTSL3,FXR1" Pubmed 26514267 Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. Pubmed 5.12E-14 8.91E-09 1.13E-10 1.43E-09 63 320 "ACTN1,RGS20,ATP1A3,SLC4A4,MPDZ,DST,CACNA1B,CFL2,HECTD1,RBM39,CRMP1,CRYM,RIPOR2,INTS1,ZC3H11A,DMD,DNM1,DPYSL2,ARRDC4,MAMLD1,EBF1,KLHL5,COPS4,ENO2,TUBA1B,TUBB3,RACK1,AMOTL2,GGT7,CIT,CYP27C1,MAP2,MYO9A,PPP3CA,MAPK10,PTPN13,PTPRD,PTX3,PPP2R3C,RGS12,FAM192A,ASAP3,SLC12A4,SNAP25,SOX11,STXBP1,SYNE2,SYN1,SYN2,MMS19,ANKRD12,DMXL2,CLASP1,PCDHB10,AP4E1,THRA,UCHL1,BCL2L13,CLIP2,CLDND1,MFF,TUBA1A,ITM2C" Pubmed 19615732 Defining the human deubiquitinating enzyme interaction landscape. Pubmed 6.21E-14 1.08E-08 1.35E-10 1.70E-09 136 1005 "ACADM,KLHL13,SRPX,GPRASP2,OGT,APBA2,APC,USP37,CASK,MARK4,DYNLL1,EIF4G3,AZGP1,ADGRB1,BARD1,MPDZ,NAE1,CALM1,CAMK2G,USP6,USP2,ARHGEF2,CDC25B,LONRF2,ZMYM4,FBXO7,QKI,HECTD1,MAP4K4,AKAP7,ARMC8,COL11A2,PREPL,CS,ARHGEF10,SIPA1L1,UBXN2A,PPP6R2,DCAF4,GPRASP1,TCAF1,DBT,SPATA2,WDR20,USP3,DTNA,E2F5,FEM1B,OPTN,KCTD3,EIF4G1,EIF4G2,COPS4,PAN3,USPL1,GPHN,CEP85L,SCML2,FECH,POLR1B,RGPD5,FLNC,ANKFY1,STAMBP,USP21,CELF1,OGA,NEURL4,USP19,TXNL4A,COPS8,CBX1,GNAL,GPT2,PRRC2B,ATE1,DDX19B,ATXN2L,IDH3A,KLHL23,IPO5,KTN1,SYTL4,MARK1,MARK3,KCTD6,BLOC1S2,MYO6,PDCD2,PGAM2,PIK3C2A,PLEC,STRN3,PPP5C,PSMA6,TMEM104,USP47,RAD17,RDX,KIF7,RNH1,MCMBP,SAFB,SUPT20H,SHMT2,AMBRA1,FBXO11,CNKSR2,USP33,KDM3A,MYCBP2,CLASP2,NSFL1C,ANKRD28,MMS19,MTCL1,TAF9,FBXW11,KIAA0930,USP22,DICER1,SIRT1,RIMBP2,TP53BP1,UCHL1,USP1,CCDC14,WRN,ZNF24,USP32P2,POLR3H,FTSJ1,DHX33,TUBA1A,NELFE,PARP11" Pubmed 20114047 Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes. Pubmed 6.27E-14 1.09E-08 1.35E-10 1.70E-09 23 51 "AP2A1,AMPD2,ATP1A1,ATP1A3,CLTC,DNM1,TNK2,VTI1B,TUBGCP4,GNAO1,MAP6,STX1B,NAPB,SNAP25,STX1A,STXBP1,SYP,KIAA1107,TUBB2A,KLC2,SLC30A3,TUBA1A,ST8SIA2" Pubmed 15347688 Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha. Pubmed 6.37E-14 1.11E-08 1.35E-10 1.71E-09 19 34 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 15144186 Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Pubmed 1.66E-13 2.88E-08 3.47E-10 4.39E-09 37 133 "CDK13,PDE8B,RIPK1,ARHGEF7,SPAG9,EPS15L1,ARHGEF6,USP6NL,ZFYVE16,TBC1D5,GIT2,DOCK2,EGFR,SRRM1,FCGR3A,DCTN2,FYB1,FYN,ATXN2L,MAP4,AFDN,DBNL,OPA1,PDPK1,SH3KBP1,MAPK3,PTPRB,KIRREL1,AP1AR,FNBP1,ZC3H13,ERBIN,DMXL2,ICAM5,R3HDM1,PARD3,TP53BP2" Pubmed 17145500 PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Pubmed 1.72E-13 2.99E-08 3.56E-10 4.50E-09 34 114 "FZD9,LRFN2,SEMA6A,LRFN1,SEMA7A,SEMA4G,ADAM23,NRP2,CALB2,NECTIN3,LRRC3B,PLXNA4,SLITRK5,SEMA3D,PLXNC1,SEMA4D,NTNG2,L1CAM,MBP,ADAM11,ADAM22,SEMA5B,PLXNB1,SDK2,PRKCB,SEMA6D,LRFN5,DCBLD1,CADM2,SEMA3B,SLC17A7,FZD3,NETO2,NETO1" Pubmed 15324660 "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." Pubmed 1.77E-13 3.07E-08 3.61E-10 4.56E-09 54 256 "USP37,SHROOM2,ARHGEF7,CAPN3,ARHGEF2,NUMBL,CLTC,HECTD1,ARHGEF6,OSBPL3,DOCK4,GAPVD1,HDAC4,GIT2,SRRM1,DENND4A,PRMT5,FER,BAIAP2,FOXO3,RAPGEF6,RNPS1,PARD3B,RASSF8,MARK3,AFDN,GIT1,HNRNPM,PFKFB2,PIK3R1,JAKMIP1,MAPKAP1,RGS12,TRA2B,PUF60,EPN2,RADIL,MYCBP2,ERC1,MPRIP,KIAA0930,CLASP1,CRTC1,FRYL,TIAM1,PARD3,TP53BP2,TSC1,TSC2,TUBB2A,UBC,KLC2,TUBA1A,FRMD6" Pubmed 15582152 A neurogenomics approach to gene expression analysis in the developing brain. Pubmed 1.99E-13 3.46E-08 4.02E-10 5.09E-09 39 147 "ADCY6,SPARCL1,MADD,NRP2,FUBP1,SCAPER,CAMK2A,CD86,ARHGEF1,COL4A5,RBM39,VCAN,CST3,PPP6R2,TM9SF4,TSPAN5,GORAB,NSG1,GABRG2,FAM19A2,IGF1,STMN1,NPR2,PCDH9,ABCB1,PKD1,PKM,LRRN3,SNRK,PTPN13,SUSD4,ROGDI,ROBO2,RTN1,PRRC2C,FAM208A,ZEB1,FSTL5,NETO2" Pubmed 17353931 Large-scale mapping of human protein-protein interactions by mass spectrometry. Pubmed 2.17E-13 3.76E-08 4.33E-10 5.47E-09 161 1284 "SPOP,UNC79,OGT,BCAS1,ARHGDIA,ARRB1,RGS20,ARRB2,CCAR2,DYNLL1,EIF4G3,ATP1B3,ATP2A2,CFLAR,ARHGEF7,FUBP1,NAE1,CALM1,CAMK2A,CAMK2B,SPAG9,RUNX1T1,CBR1,CCNH,LRBA,ARHGEF2,SEPT7,CDC25B,MAGI1,CDO1,TBRG4,COPB2,SRSF11,CNOT8,CLTC,MAGED1,TBPL1,COX4I1,CDC42BPB,CSNK1E,OSBPL3,DOCK4,GAPVD1,HDAC4,MATR3,DGKB,GIT2,DBT,DCTN1,ZBTB24,PDCD6IP,RASGRP1,EEF1D,KMT5B,ASB3,EIF4G1,EIF4G2,COPS4,EPB41,EPB41L2,SRRM1,DENND4A,FDFT1,BAIAP2,SYNCRIP,NOP56,NELFCD,SMC2,UFM1,AP4B1,NEURL4,FAM120B,IQGAP2,MTHFD2,C15orf41,INPP5K,MALT1,TTBK1,RNPS1,HTATSF1,GSN,FAM107A,RASSF8,DDX19B,GABARAPL2,SMAP1,ICA1,KHK,LIG4,LIMS1,MARK3,MEST,MKLN1,AFDN,MOV10,GIT1,DBNL,MYO6,HNRNPM,OGG1,OPA1,PFKFB3,FAM98B,OLA1,PIK3R1,STRN3,PPM1B,PRKAB2,PSMA6,SNRK,PTK2,RAD51D,RASGRF2,CCDC82,SARS,ATXN2,TRA2B,HSPA4L,PUF60,SGK1,SHMT2,CNKSR2,PPP4R3A,RADIL,SIRT2,CDK5RAP3,SMARCA4,SNRPN,MYCBP2,ERC1,CDK19,CLASP2,TROVE2,MPRIP,SEPT8,TTBK2,MMS19,FBXW11,KIAA0930,CLASP1,FRYL,AKTIP,TIAM1,PARD3,TSC1,TSC2,RPRM,RPL7L1,CLEC2L,KLC2,XRCC4,SPIRE1,NELFE,PARP11,RTN4,HNRNPA3,ACTR3B,JMJD1C,FRMD6,LAS1L,JPH3" Pubmed 9205841 Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 3.38E-13 5.87E-08 6.67E-10 8.44E-09 32 104 "MADD,SYNJ2,MTMR3,DCLK1,AKAP6,CLOCK,ENTPD4,ARHGEF10,ERC2,RIPOR2,SNPH,ZFYVE16,RUSC2,KIAA0319,SEC16A,DNAH9,SUGP2,EZH1,SRCAP,PRUNE2,DIDO1,MYO6,NRCAM,PTPRN2,CHD9,PDZD2,HECW1,ANKRD28,MCF2L,RIMBP2,KAT6B,CABIN1" Pubmed 12421765 Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. Pubmed 4.08E-13 7.10E-08 7.98E-10 1.01E-08 36 130 "HACE1,SEMA6A,CARNS1,EP400,MADD,SPTBN4,CADPS,DST,SYNJ2,SCAPER,THSD7A,TAOK2,HECTD1,WHRN,SH2B1,SIPA1L1,CNTNAP2,ARHGAP32,HDAC4,SPOCK2,KIAA0319,FEM1B,CELSR3,MEGF10,GRB10,NRCAM,PTPRN2,BTBD3,CDK5RAP2,MBD5,MYO16,PDZD2,MCF2L2,SSPO,FAM208A,PUM2" Pubmed 9628581 Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 4.54E-13 7.88E-08 8.76E-10 1.11E-08 32 105 "ADGRB3,SPAG9,LARGE1,CACNA2D2,NRXN3,SUSD5,GREB1,CCDC144A,KIAA0586,ARMCX2,JAKMIP2,RASA4,VPS13B,CHST15,ERAP1,PRRC2B,PCLO,ZNF862,OPA1,MAPKBP1,FNBP1,IQSEC2,SPART,SSPO,CEP68,JMJD6,PLCB1,MGRN1,WSCD1,TRIM2,FAM189A1,ADAMTSL3" Pubmed 23602568 The protein interaction landscape of the human CMGC kinase group. Pubmed 6.34E-13 1.10E-07 1.21E-09 1.53E-08 102 694 "CLK4,AXIN2,ESYT2,EP400,APC,CDK10,CASK,ARNTL,CDK13,DYNLL1,ATP1A1,AZGP1,BACH1,CCNH,CCNT1,EVI5L,FOXN3,HOMER3,RBM39,SIPA1L1,RIMS4,YTHDC1,DDX46,MED12,PDCD6IP,DUSP9,EDIL3,HIPK3,FRY,SUGP2,RASA4,SRPK3,SRRM1,ERBB2,ERCC2,CDKL3,NSRP1,KAT8,FGF12,FGFR1,BAIAP2,FHL1,SEC23B,FLT1,NOP56,NSG1,NEURL4,KIAA1841,RNPS1,MSL3,STON1,DIDO1,CLASRP,FAM222A,KCNN2,SRSF12,AFF1,HNRNPM,NOVA1,CDK18,PDPK1,PKM,PPP5C,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,MASP1,LAMA1,PTK2,CEP97,RBBP6,HKR1,RDX,ZMAT4,RPS6KA2,ATAT1,NCBP3,FAM192A,MAPK12,TRA2B,RBM34,ERC1,ARHGAP26,SPTAN1,CDK19,NXT2,STAU1,OBSL1,TEK,SIRT1,CBX5,FAM124A,CDK20,TRPS1,DHX33,PPP1R3F,KCNAB1,FIP1L1,NELFE,ZNF30" Pubmed 10512203 Exchangeable gene trap using the Cre/mutated lox system. Pubmed 7.08E-13 1.23E-07 1.34E-09 1.69E-08 82 506 "MAP4K3,PKP4,TMEFF1,WASF1,CCNT1,ARHGEF2,SRSF11,HECTD1,MAP4K4,CNN3,NCOR1,NCOR2,OSBPL3,SIPA1L1,PUM1,HDAC4,IST1,YTHDC1,WDR20,DTNB,TSPAN5,HIPK3,SUGP2,MBNL2,COPS4,EPB41L2,NSRP1,POLR1B,FGFR1,SYNCRIP,CAMKK2,TRAF3IP2,C15orf41,SEPT9,AHDC1,TXNL4A,GLI2,RAB30,TNRC6A,STMN2,PACSIN2,RBPJ,KIFC3,MARK3,MAT2A,PKM,MAPKAP1,POLR2F,PPM1B,KANSL1,WBP1L,QRICH1,PTPRG,KIRREL1,PCMTD2,RMI1,CSRNP3,GALNT10,SEC31A,EPN2,TET1,MBD5,TEX2,ZNF423,ERBIN,KANK1,TACC1,CAMTA1,TAF9,TBCEL,SMG6,TCF4,TCF12,CLASP1,FRYL,DICER1,TIAM1,LRRC8A,PARD3,C9orf85,SLC38A1,JMJD1C" Pubmed 10819331 Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.52E-12 2.64E-07 2.84E-09 3.59E-08 31 103 "OSBPL8,PDZD4,BEGAIN,TRMT9B,PITPNM2,LRFN1,ZFAT,DPP10,LRCH2,EP400,CCDC146,MYH7B,PHF12,SUGT1P4-STRA6LP-CCDC180,SCAPER,WHRN,GAPVD1,CERCAM,TNRC6A,MARK1,CNTN3,NLGN3,SEMA5B,SDK2,ERI2,SEMA6D,SYBU,NLGN1,FAM214B,BTBD7,MBD5" Pubmed 11256614 Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. Pubmed 1.60E-12 2.79E-07 2.97E-09 3.75E-08 83 523 "ACADM,NDRG2,INTS2,SYT13,BIN1,APOC1,USP37,CCAR2,GPC2,NFS1,TBRG4,CNOT8,PPT2,FBXO7,MROH8,PNPLA8,ARHGAP24,AIF1L,DBN1,ELMO1,TMEM130,RAB39B,DNAJB6,GOLT1B,COQ7,NCALD,CD320,NSRP1,FAM198B,RACK1,ZMYND10,MEX3B,HPCAL4,PSD2,SYT3,PDLIM5,MSANTD4,GALNT15,SPIN1,CCDC184,FAM107A,DDX19B,GABARAPL2,SYNPO,AGBL5,KHK,STMN1,NCOA7,PCSK5,GPR85,OLA1,PKM,MTRF1L,KANSL1,PTN,QDPR,ROGDI,TRIM68,NUDT11,TMLHE,FAM192A,AP1AR,FOXRED1,FAM214B,KANSL3,LIMCH1,FAM126B,TSPYL2,KLHL7,TCF12,SLC35G2,MTMR14,ZNF346,SYNPO2,SSBP2,PLEKHH2,USP1,KLC2,TFIP11,ITM2C,PHTF2,TIGD6,SENP7" Pubmed 16944949 Identification of 14-3-3epsilon substrates from embryonic murine brain. Pubmed 1.65E-12 2.87E-07 3.02E-09 3.82E-08 35 129 "SYN3,OGT,LRCH2,MARK4,KSR1,CBR1,DCLK1,ARHGAP33,CLTC,HOMER3,ERC2,RIMS2,GIT2,DBN1,BAIAP2,MSANTD4,BRSK1,DCLK2,KIF5A,MARK1,MARK3,GIT1,DBNL,NF1,ATAT1,R3HDM2,WDR37,CCDC88A,ERC1,MPRIP,SYN1,SYN2,CRTC1,TSC1,DOCK8" Pubmed 22589738 Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. Pubmed 1.85E-12 3.21E-07 3.35E-09 4.23E-08 44 193 "ZNF608,ZFAT,BACH1,LARGE1,HAPLN1,CRY2,CNTNAP2,POM121,PDCD6IP,SNX29,EPHB1,HSPA12B,FKTN,MAD2L2,PDLIM5,PCDH17,LUZP2,DCLK2,BACH2,NEGR1,SLC6A17,ITPKB,LYPLAL1,NCAM2,KSR2,SNX10,PSAT1,RORB,TNFRSF19,FAM81A,LHPP,CLSTN2,NKAIN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,CADM2,ADAMTS9,DNAH10" Pubmed 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 2.53E-12 4.40E-07 4.53E-09 5.73E-08 87 565 "NDRG2,FMNL2,ELFN2,ADD1,ESYT2,PKP4,NUMB,DST,SYNJ1,SYNJ2,CAST,SCARB1,SEPT7,LRRFIP1,MAGI1,NUMBL,EPS15L1,CNN3,FAM171B,USP6NL,ARHGAP32,GAPVD1,ZFYVE16,IST1,DBN1,EEF1D,EGFR,EIF4G1,EIF4G2,EIF5,PLEKHA1,EPB41,ERBB2,RACK1,SEC24B,BAIAP2,NOP56,SPECC1,PDLIM5,SEPT9,ARFIP1,PACSIN2,ATXN2L,AGFG1,IL6ST,KTN1,MAP4,MARK3,AFDN,DBNL,MYO6,OLA1,CCSER2,XRN1,PKM,PLEC,EPB41L4B,SH3KBP1,RDX,RPL15,PUF60,FERMT1,ABLIM3,EPN2,SLC12A2,INAVA,LIMCH1,SNAP25,FAM126B,ERC1,SPTAN1,ITPRID2,ERBIN,MPRIP,NSFL1C,DOCK9,TMPO,PARD3,TP53BP2,UBC,KLC2,SH3GLB2,SLC38A1,CIAPIN1,RTN4,TTC7A,NHSL1" Pubmed 16303743 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Pubmed 3.63E-12 6.31E-07 6.44E-09 8.14E-08 72 430 "SYS1,C1QTNF1,ADGRF5,C1QTNF3,SEMA6A,PI16,CHID1,SLC2A11,ADAM15,PROM1,ENTPD6,MS4A7,STOML1,TMEM184B,SUMF2,CS,MYADM,RRP7BP,LYPD1,SEZ6L2,APH1A,PCOLCE2,ELN,SLC43A2,ARMCX1,FCGRT,C2orf88,POMT1,ATP2C1,ERGIC3,DLL3,SARAF,GHDC,LYVE1,GPR34,PLPP7,SPACA9,CACFD1,SLC2A6,MAN1B1,VSIG4,ELOVL5,SCIN,CLEC18A,AQP11,MATN2,KCTD6,PAX6,NLGN3,RETREG2,DRAM2,SLC26A11,PIGG,TMEM145,TTC13,PRRT2,SPP1,DBNDD2,ALG1,CYB561A3,TMEM9,RELL2,LRRC8A,RUSC1,HSPBP1,RPRM,CLDND1,ATP6V0E2,SLC38A1,GDPD5,TMEM178A,ITM2C" Pubmed 15747579 Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Pubmed 3.99E-12 6.93E-07 6.95E-09 8.79E-08 55 284 "VWA5B2,KIAA1324,LTBP4,LCORL,STX16,HIP1R,CLTC,SLC4A8,CREM,SIPA1L1,CNTNAP2,RUBCN,WDR20,STARD3NL,PAN3,FECH,MED12L,FGF12,SEC23B,FLT1,UFM1,USP21,KIAA1841,IGSF5,USP19,GNAO1,PRRC2B,FICD,PSIP1,HECTD2,RTL5,NTRK2,OXTR,PFKFB3,SGSM1,DGLUCY,SARS,ATXN7,RADIL,KDM4B,SP2,LARP4,NEK4,JMJD6,MTCL1,EXOC7,DNMBP,AGTPBP1,BHLHB9,PPIL6,SLC35A4,ZNF24,ZFP41,MEIS3,JMJD1C" Pubmed 15840001 Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Pubmed 4.00E-12 6.95E-07 6.95E-09 8.79E-08 80 504 "MAP4K3,PKP4,TMEFF1,WASF1,CCNT1,ARHGEF2,SRSF11,HECTD1,MAP4K4,CNN3,NCOR1,NCOR2,OSBPL3,SIPA1L1,PUM1,HDAC4,IST1,YTHDC1,WDR20,DTNB,TSPAN5,HIPK3,SUGP2,MBNL2,COPS4,EPB41L2,NSRP1,FGFR1,SYNCRIP,CAMKK2,TRAF3IP2,C15orf41,SEPT9,AHDC1,TXNL4A,GLI2,RAB30,TNRC6A,STMN2,PACSIN2,RBPJ,KIFC3,MARK3,MAT2A,PKM,MAPKAP1,POLR2F,PPM1B,KANSL1,WBP1L,QRICH1,PTPRG,KIRREL1,PCMTD2,CSRNP3,GALNT10,SEC31A,EPN2,TET1,MBD5,TEX2,ZNF423,ERBIN,KANK1,TACC1,CAMTA1,TAF9,TBCEL,SMG6,TCF4,TCF12,CLASP1,FRYL,DICER1,TIAM1,LRRC8A,PARD3,C9orf85,SLC38A1,JMJD1C" Pubmed 16919269 A global genomic transcriptional code associated with CNS-expressed genes. Pubmed 4.24E-12 7.37E-07 7.29E-09 9.22E-08 57 301 "APAF1,SEMA4G,MARCH3,ADAM23,NRP2,CLDN10,LRBA,L3MBTL4,CHN1,PCYT1B,RIMS2,SNPH,EBF1,EDNRB,HIPK3,SPEG,DLC1,GCNT2,POLL,DCLK2,GRIA2,METTL21A,EFHB,MEIS2,MITF,PAX6,GPR85,OLA1,KCTD15,APTX,CNTLN,PTCH1,PTPRE,PEX2,OXR1,FIGN,RGS4,ZFHX4,SALL1,SATB1,SGK1,ARX,CPEB3,NLGN1,DZIP1,ST8SIA1,SOX11,DOK5,TCF4,TCF12,ZFPM2,AKTIP,GALNT17,TMPO,TRPS1,TTC3,ZIC2" Pubmed 25814554 Phospho-tyrosine dependent protein-protein interaction network. Pubmed 8.00E-12 1.39E-06 1.35E-08 1.71E-07 69 410 "OSBPL6,C1QTNF3,MYH7B,CCDC74A,NUMB,BTK,SCAPER,CA8,KRIT1,USP2,LRRFIP1,SOCS6,CHN2,PLEKHB1,NGEF,LETMD1,SH2B1,APPL1,DCAF8,DBN1,ZBTB24,PARD6A,WDR20,DTNA,E2F6,PHC2,ASB3,ING4,TNK2,FER,FGF12,FGF13,BAIAP2,SEMA4D,WDR83,FYB1,FYN,ZMAT1,CYP46A1,AHDC1,LNX1,PRRC2B,GRB10,MATK,BEX5,NME4,PDPK1,PIK3R1,ZNF655,PPARA,VSTM2L,PTK2,KCTD17,GSTCD,SH3BP2,ARFGAP1,DOK5,ZHX3,SPTB,NXT2,MLST8,OBSL1,TNS2,TNS1,TSC1,CCDC14,ANKS1B,MSRB3,SOCS4" Pubmed 28065597 A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Pubmed 8.02E-12 1.39E-06 1.35E-08 1.71E-07 70 419 "USP31,HECW2,ALK,CCDC146,CDK13,ATP1A1,ALDH7A1,KIF1A,MTMR3,MTMR2,CDC25B,ZMYM4,SRSF11,RBM39,AATK,CSF1R,CENPL,SEC16A,DUSP9,AASDH,SNX29,EGFR,EIF4G2,ING4,EPB41L2,SRRM1,ERBB2,ERBB4,FOXO3,GABRA3,SYT17,SRRM4,GLUL,HTATSF1,GRIK4,PTPRT,KIT,MAP4,PPM1L,XRRA1,MYO9A,NF1,PDE1C,DUSP26,ZFYVE21,TRHDE,PPM1B,PPP3CA,RASGEF1B,MTMR10,PTPRB,PTPRH,PID1,DUSP15,RET,RPS20,SBF1,TRA2B,FAM126B,DOP1A,DIP2A,ZC3H4,SUPT5H,AGTPBP1,TEK,DNAH7,MTMR14,RUNDC3B,ZBTB14,EML6" Pubmed 19058789 A common variant in DRD3 receptor is associated with autism spectrum disorder. Pubmed 8.31E-12 1.44E-06 1.39E-08 1.76E-07 34 129 "ADRA1B,APAF1,CAMK2B,CCK,CHRNA4,CNR1,CSNK1E,DLX1,SLC12A6,RASGRP1,PPP1R1B,GABRA3,GABRB3,MCHR1,GRM8,INPP1,KCNN3,NPY,NPTX2,NRCAM,OPRL1,NLGN3,RELN,HES6,SNAP25,COBL,NR2E1,TSC1,TSC2,UBE2H,UBE3A,SLC30A4,ST7,NLRP3" Pubmed 20360068 Systematic analysis of human protein complexes identifies chromosome segregation proteins. Pubmed 8.60E-12 1.50E-06 1.42E-08 1.80E-07 143 1149 "AP2A1,BEGAIN,OGT,APC,ARRB1,ARRB2,CCAR2,DYNLL1,AZGP1,BACH1,BCL7A,BLM,SYNJ2,CACNA2D1,SPAG9,PRC1,C1orf52,CDC25B,ZMYM4,LRWD1,COPB2,CNOT8,EPS15L1,PLAA,CLTC,ABCG2,HOMER3,AHCTF1,NSL1,CPS1,RBM39,AKAP12,CRY2,TRIM69,CSNK1E,DCAF4,GAPVD1,DCAF8,LIN54,MATR3,AIF1L,DCTN1,DDX46,PARD6A,FAM107B,PDCD6IP,EDIL3,PHF20L1,EIF4G1,COPS4,DCTN4,VPS13B,GPHN,TUBA1B,RACK1,CEP78,PRMT5,KAT8,FECH,MAD2L2,SYNCRIP,RGPD5,NOP56,DCTN2,SPECC1,FYN,NEURL4,GATM,TUBGCP4,WASHC2A,BRD8,MSL3,CBX1,HTATSF1,GNAL,GNAO1,PRRC2B,HP,DHX35,HSF2,MSL1,KIFC3,IPO5,PAXBP1,SYTL4,LYPLAL1,POC1B,MOV10,NACA,PCBP3,CHAMP1,OGG1,PDE4D,CCSER2,PKM,STRN3,RETREG2,SH3KBP1,PPP2R5E,KANSL1,PPP2R3C,CEP97,USP47,DPF2,PBRM1,TCP11L1,CLIP1,ZNF331,RMI1,TRA2B,COPZ1,AMBRA1,DHX30,KANSL3,ZFP1,SMARCA4,SMARCC2,CDK5RAP2,RCOR3,UHRF1BP1L,CLASP2,POGZ,SS18,MPRIP,TTBK2,KANK1,ZC3H4,MTCL1,CLASP1,SYNE1,SIRT1,ZNF106,TMPO,TP53BP1,TPM1,STXBP4,TRPS1,GORASP1,XPO1,TFIP11,STOX2,MRPL47,HNRNPA3" Pubmed 18187620 Identification of host proteins required for HIV infection through a functional genomic screen. Pubmed 8.82E-12 1.53E-06 1.45E-08 1.83E-07 53 273 "XKR4,TAOK1,SMIM29,PHF12,ATP6V0A1,ST3GAL5,HIP1R,CCNT1,USP6,DLGAP1,RAB28,C4orf33,NCOR2,RIMS4,ARHGAP32,GAPVD1,DNAL1,TIAM2,RUSC2,ALKBH8,EDNRA,TMTC1,EGFR,KMT5B,STARD3NL,RABEPK,RRAGB,TMEM132C,AGAP2,RGPD5,GCK,MMADHC,HTATSF1,GABARAPL2,AGBL5,SOWAHA,ITPKA,MAP4,NCR3LG1,ERI2,KCNIP3,SEC14L1,ANKRD6,KDM4D,SPTAN1,SEPT8,STAC2,FBXW11,FAM200B,DOK6,CLDND1,DHX33,RNF170" Pubmed 15572359 Proteomic analysis of in vivo phosphorylated synaptic proteins. Pubmed 1.06E-11 1.83E-06 1.71E-08 2.17E-07 21 52 "AP2A1,PKP4,ARHGEF7,CACNB4,CAMK2A,CAMK2B,FAM131B,DBN1,PCLO,MAP2,MAP4,MAPT,MBP,SAMD14,PALM,MAPK3,RTN1,NFASC,STXBP1,PLCB1,GPRIN3" Pubmed 23455924 A Y2H-seq approach defines the human protein methyltransferase interactome. Pubmed 1.08E-11 1.87E-06 1.74E-08 2.19E-07 61 342 "INTS2,MYH7B,CCDC74A,SOCS6,QKI,CCDC151,ZFP28,PDE4DIP,PYGO1,KIAA0408,DCAF8,CENPL,RASSF2,ZBTB24,NR1D2,PHC2,PHF20L1,ASB3,ING4,PRMT5,BAIAP2,SYNCRIP,NELFCD,WDR83,AK8,FYN,MALT1,SPIN1,GLYR1,LNX1,ATE1,RASSF8,KIFC3,SMAD9,NFIX,NME4,NECAB2,PPARA,KANSL1,RAD17,KCTD17,GSTCD,OGDHL,RCOR3,KDM4B,KDM3A,DIP2A,JMJD6,TACC1,MLST8,C18orf54,ITGB3BP,NR2C2,TSC1,ZKSCAN5,CCDC14,SH3GLB2,DNALI1,FIP1L1,JMJD1C,FRMD6" Pubmed 22802532 Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Pubmed 1.19E-11 2.08E-06 1.90E-08 2.41E-07 18 38 "ACTN1,MTA3,NUMB,PTBP2,CAMK2B,CAMK2G,RAB28,DBN1,DNM1,ERBB4,GLUL,NOVA2,PAX6,GPR85,DZIP1,SNAP25,MCF2L,PUM2" Pubmed 26167880 SR protein kinases promote splicing of nonconsensus introns. Pubmed 1.31E-11 2.28E-06 2.08E-08 2.62E-07 63 361 "SFMBT2,SPTBN4,CDK13,MYOM1,AP1M1,ZMYM4,SRSF11,ANKRD35,RBM39,MATR3,IP6K1,YTHDC1,DDX46,DNAH9,CELSR3,EIF4G1,MFSD10,SRRM1,DENND4A,RASL12,F5,TUBA1B,ZMYND10,FGFR3,SCARA3,ANKFY1,HRASLS5,ZNF234,CYP46A1,GHR,HTATSF1,PRRC2B,DIDO1,CLASRP,HNMT,MAP4,NF1,SDK2,EPB41L4B,VSTM2L,RASGRF1,RBBP6,ZFHX4,SAFB,TRA2B,MYCBP2,ERC1,ZC3H13,CLASP2,PHLDB1,PRRC2C,MTCL1,CLASP1,FAM189A1,CRTC1,ASXL3,TMPO,HSPBP1,MICU3,FIP1L1,EPM2A,HNRNPA3,JMJD1C" Pubmed 17634366 Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. Pubmed 1.93E-11 3.36E-06 3.03E-08 3.83E-07 38 161 "ATP1A1,ATP1A3,SEPT7,CLTC,CNTN1,CNRIP1,DNM1,DPYSL2,PDCD6IP,ENO2,TUBA1B,ATP5PD,GLUL,GNAO1,TPPP,GSTM5,HBA1,IDH3A,MBP,TAGLN3,NEFH,CLDN11,PKM,SEPT4,RDX,SIRT2,NAPB,SNAP25,SPTAN1,NFASC,SEPT8,STXBP1,PLCB1,SYN1,SYN2,UBC,UCHL1,TUBA1A" Pubmed 24457600 The central role of EED in the orchestration of polycomb group complexes. Pubmed 2.32E-11 4.02E-06 3.59E-08 4.54E-07 193 1719 "ABCF1,AS3MT,ACTN1,MTA3,AP2A1,AP2A2,ZNF687,OGT,EP400,PKP4,EPB41L5,ARHGDIA,CDK13,NUMB,CCAR2,DYNLL1,ATP1A1,ATP2A2,ATP6V0A1,SYNJ1,FUBP1,AP1M1,CACNB4,CALM1,CBR1,LRRFIP1,COPB2,EPS15L1,CPNE6,PLAA,MYL6B,CLTC,CNN3,RCHY1,AHCTF1,SEC31B,CDC42BPB,RBM39,SIPA1L1,PDE4DIP,PUM1,MYADM,GAPVD1,MATR3,INTS1,DAPK1,DBN1,DBT,YTHDC1,DCTN1,MYEF2,TIAM2,ZC3H11A,SEC16A,MED12,ACOT8,PDCD6IP,TOM1,FARSB,DNM1L,PHC2,FCF1,EEF1D,YAF2,SUGP2,MBNL2,EIF4G1,MFSD10,EZH1,ACSL4,TUBA1B,PTK2B,SCML2,RACK1,SYNCRIP,RGPD5,ANKFY1,NOP56,SMC2,SPECC1,PDLIM5,USP21,ATP6V1H,ATP2C1,KHDRBS3,CELF1,STAU2,CHL1,SEPT9,TCERG1,COPS8,RNPS1,GLYR1,ZNF638,CBX1,KDM2B,FERMT2,TDRKH,DIDO1,CIT,GSN,KAT7,ADAMTS6,ATXN2L,SLC35G1,IPO5,KTN1,LIMS1,PAXBP1,AFDN,MOV10,MYO6,HNRNPM,NME4,FAM98B,OLA1,PIK3C2A,XRN1,PKM,PLEC,PSAT1,EXOSC10,VPS13C,PSMA6,LAMA1,ENOX1,RDX,DPF2,PBRM1,RPL15,ZC3H14,RPS20,CLIP1,RYR3,NCBP3,SAFB,ATXN2,CASC3,TRA2B,COPZ1,PUF60,MYO18A,FBXO11,SEC31A,NUBPL,EPN2,DHX30,SIRT2,CPEB4,SMARCA4,SMARCC2,CDK5RAP2,LIMCH1,SNRPN,RBM34,MYCBP2,ZC3H13,SPTAN1,POGZ,MPRIP,STAU1,ZC3H4,SUPT5H,DNAJC9,MMS19,MLST8,FAM208A,SZT2,SYNE1,NSD1,PUM2,TMPO,TP53BP1,ZNF346,TRIO,TUBB2A,RPL7L1,UBTF,VGF,TBC1D15,KLC2,RICTOR,XPO1,ZSCAN26,TFIP11,SMARCAD1,DHX33,INTS3,VPS35L,FIP1L1,HNRNPA3,FXR1,LAS1L" Pubmed 16964243 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Pubmed 2.39E-11 4.16E-06 3.68E-08 4.65E-07 78 503 "ABCF1,TAOK1,ZNF687,BEGAIN,AMPD2,APC,CDK13,NUMB,EIF4G3,BACH1,BLM,FUBP1,KALRN,PRC1,ARHGEF2,LRRFIP1,TBRG4,EPS15L1,ARHGEF6,AHCTF1,NCOR1,YTHDC1,ZC3H11A,SEC16A,DPYSL2,FAM13A,EIF4G1,EPB41L2,GPHN,SRRM1,NSRP1,AGAP3,STAU2,SEPT9,BRD8,ZNF638,GRB10,DIDO1,KAT7,ATXN2L,IFI16,STMN1,MAP4,AFDN,DBNL,HNRNPM,CHAMP1,PDE3A,PDE4D,PKM,STRN3,USP47,RBBP6,PBRM1,MCMBP,CLIP1,SAFB,TRA2B,ARFGAP1,EPC1,KIF13A,FNBP1,ERC1,ZC3H13,RBM26,ZC3H4,MTCL1,TAF6,EXOC7,SIRT1,TP53BP1,METTL3,TBC1D15,KLC2,ZXDA,FIP1L1,NELFE,LAS1L" Pubmed 15217342 The synaptic vesicle cycle. Pubmed 3.15E-11 5.48E-06 4.81E-08 6.08E-07 16 31 "SYN3,PPFIA4,PPFIA3,RIMS4,ERC2,RIMS2,SV2B,CPLX2,CPLX1,PCLO,STXBP5,SNAP25,STXBP1,SYN1,SYN2,SYP" Pubmed 25826454 Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Pubmed 3.20E-11 5.56E-06 4.84E-08 6.12E-07 33 128 "LRFN2,ALCAM,LRFN1,IGDCC4,IGLON5,CNTN1,IGDCC3,NECTIN3,CSF1R,LRIG1,BOC,CDON,SPEG,FLT1,CHL1,MALT1,ADGRA3,PTPRT,LINGO1,NEGR1,NCAM2,NRCAM,IGSF11,CNTN3,PRTG,LRRN3,KIRREL1,LRFN5,TEK,ICAM5,LRRC24,TRIO,CADM2" Pubmed 9734811 Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 3.73E-11 6.49E-06 5.60E-08 7.08E-07 29 102 "PPFIA3,HIP1R,ARHGEF2,MAP4K4,CRY2,AATK,OSBPL3,SOCS5,DZIP3,PPP6R2,HEPH,MFAP3L,ZC3H11A,POM121,SNAP91,ADGRV1,OGA,KIF21A,UHRF1BP1L,ARHGAP26,CLASP2,PHLDB1,COBL,ASTN2,FBXW11,SIN3B,CLASP1,OBSL1,CRTC1" Pubmed 17207965 "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." Pubmed 4.38E-11 7.61E-06 6.51E-08 8.23E-07 188 1675 "C3orf14,TRMT9B,LCORL,NT5C3B,PHYHD1,VAT1L,ARRB1,CCDC74A,CHID1,SEC11C,LDLRAD4,CFAP410,CA4,CA8,NFS1,KYAT1,AP4M1,CDO1,CBARP,C7orf61,RAB28,PPT2,QKI,LY86,ARMC8,LETMD1,RCHY1,CRHBP,HAPLN1,GDA,PDE4DIP,PLXNA4,DCAF4,KATNAL2,SNPH,CENPL,IST1,TMEM170A,SCRN1,PABPC5,DBI,ELMO1,B3GAT3,GUCD1,ALKBH8,SPOCK3,DMTF1,RCAN1,DTNA,FIS1,GOLT1B,SEZ6L2,TSPAN5,EDN3,APH1A,MRO,EIF5,MRNIP,C3orf18,HSD17B14,MRPL37,RASL12,SIRPB1,GMPR2,CLVS1,SH3YL1,FCGR3A,PRKAG2,SCARA3,EVL,DCTN2,C2orf88,WDR83,TMEM107,AK8,FAM49B,ERGIC3,ST6GALNAC3,TPPP3,HRASLS5,C15orf41,RUNDC3A,COPS8,GNAL,LILRA2,BTN2A1,GSTM5,BVES,RASSF8,DDX19B,ELOVL5,LRRC25,FAM69A,KCNJ5,KCNN3,KPNA5,PACRG,CLEC18A,AQP11,KCTD6,MIA2,KITLG,POC1B,DBNL,MSR1,TAGLN3,PALM,ETFRF1,TMOD2,DUSP26,PIK3R1,FAM218A,RETREG1,KCTD15,SLC25A23,MTRF1L,ANKRD16,PPM1B,PPP3CC,NKAIN4,DIRAS2,CYBC1,ELOVL2,C1orf109,ZSCAN2,PPP2R3C,BEND5,RBBP6,KHDRBS2,DUSP15,PRRT2,MRPS18A,DCUN1D2,KLHDC8A,MRAP2,PTGR2,CCDC112,SCP2,ZNF821,COPZ1,ST6GAL1,CCDC92,NUBPL,CDK5RAP3,NAPB,ARFGAP1,COA1,ANKRD36,SNAP25,CABCOCO1,FAIM2,ZNF415,RBM34,NMNAT2,IZUMO4,ZNF302,ELOVL4,APOM,NUDT10,SYP,SYPL1,RNF175,C18orf54,ZMAT3,AKTIP,ACTR6,ERCC6L2,TMPO,C9orf85,CHST5,RPRM,RPL7L1,SLC35A4,GORASP1,CLDND1,CFAP298,ZNF19,TMEM198,PROCA1,FTSJ1,PRTFDC1,DNALI1,KCNAB1,ITM2C,PARP11,SMIM8,MSRB3,SOCS4" Pubmed 23431145 The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Pubmed 4.46E-11 7.76E-06 6.57E-08 8.31E-07 27 90 "NRP2,CCK,ZNF521,NCOR2,CRYM,PLXNA4,SV2B,EMX2,ETV1,PPP1R1B,FGFR3,ALDH1L1,GNAL,UBE2QL1,KCNQ3,MEST,MMP17,NCAM2,PAX6,PTPRO,ROBO1,ROBO2,RORB,TCF4,HEY1,PRDM8,ACTR3B" Pubmed 17953485 Regulatory pathway analysis by high-throughput in situ hybridization. Pubmed 5.93E-11 1.03E-05 8.66E-08 1.09E-06 27 91 "ADCY8,CALB1,CALB2,CCK,CHRNA4,LHX2,PDE4DIP,OPTN,PLXNC1,FGF14,PCDH17,PRUNE2,PTPRT,IGFBPL1,PAX6,PDE1C,PDE1B,NKAIN4,RASGRF1,RORB,ARX,SLA,ZNF423,SST,NR2E1,WNT7A,TRIM9" Pubmed 28558017 A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. Pubmed 6.38E-11 1.11E-05 9.24E-08 1.17E-06 25 79 "PCDH19,SEMA6A,ALCAM,PCDH10,SEMA7A,CDH2,LYPD1,PLXNC1,TENM1,EPHB1,NRN1,GFRA2,NTNG2,KIT,NTRK2,SDK2,LRRN3,RET,LGI2,EPHA10,CLSTN2,ASTN2,VGF,NETO2,NETO1" Pubmed 19571125 Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. Pubmed 6.51E-11 1.13E-05 9.36E-08 1.18E-06 15 28 "CALB2,LDB2,LHX2,ENO2,ETV1,GAD1,MBP,NEFH,PAX6,RELN,RORB,ARX,SATB2,CUX2,SLC17A7" Pubmed 21565611 Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Pubmed 7.26E-11 1.26E-05 1.04E-07 1.31E-06 79 524 "ACTN1,WDR35,CC2D2A,OGT,EP400,EPB41L5,DYNLL1,ATP1A1,ATP2A2,ATP6V1G2,CALB1,CALM1,CDH2,MAP4K4,VCAN,CNTNAP2,ERC2,LIN54,DNAL1,DBN1,ZC3H11A,SEC16A,DNM1,DPYSL2,ABCA8,TUBA1B,TUBB3,FLNC,NEURL4,CPLX1,CNTRL,TPPP,GRB10,GSN,HBA1,MAP2,MAP4,MAP6,DBNL,MSR1,MYO5A,NACA,HNRNPM,NEFM,PCBP3,PALM,PAX6,PFKFB2,PKD1,PKM,PLEC,STRN3,PRKACB,VPS13C,PSMA6,ANKHD1,PTPN13,QDPR,CEP97,RNH1,PCMTD2,ZC3H14,FAM161B,NAPB,IFT122,SPTAN1,STXBP1,SYN2,MMS19,KLHL4,RPGRIP1L,SIK3,HSPBP1,TUBB2A,UCHL1,TUBA1A,NAV3,UBE3B,IFT88" Pubmed 23382691 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. Pubmed 8.08E-11 1.40E-05 1.14E-07 1.44E-06 42 199 "FMNL2,TBC1D14,CADPS,CACNA1I,MAGI1,CNTN1,CNTNAP2,ARHGAP24,ELMO1,DOCK2,DPP6,FRY,KMT5B,EPB41L2,MEGF10,PTPRT,BACH2,SHISA6,IL6ST,PIK3AP1,LRP1B,MGAT3,MX1,ALDH1L2,CDK18,JAKMIP1,VPS13C,CCDC40,ROBO2,HUNK,SBF1,ST6GAL1,SEPHS1,SMARCD3,ZNF423,MPRIP,TEK,CDH22,PRRT1,CSMD1,PDSS2,DNAH10" Pubmed 9455477 Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. Pubmed 9.42E-11 1.64E-05 1.32E-07 1.67E-06 20 52 "ADCY6,APAF1,GAS7,ZMYM4,PREPL,IPCEF1,SIPA1L1,SEC14L5,KIAA0408,GPRASP1,ZBTB24,SGSM2,FEM1B,MBNL1,PLXNB1,ZHX3,ZBTB43,ARHGEF9,ATMIN,FLRT2" Pubmed 27107014 An inter-species protein-protein interaction network across vast evolutionary distance. Pubmed 1.36E-10 2.36E-05 1.89E-07 2.39E-06 74 483 "C1QTNF1,SPOP,BBOX1,GPRASP2,OGT,RGS20,CAMK2B,CAPN3,CBS,ZBED1,EVI5L,CFL2,COPB2,RCBTB2,CNOT8,QKI,HOMER3,FHL5,TRIM69,SEC24C,PDE4DIP,TBC1D5,JAKMIP2,KLHL3,PHC2,OPTN,HSD17B14,KATNAL1,AMOTL2,SEC23B,KHDRBS3,SDCBP2,GAD1,TUBGCP4,LNX1,PACSIN2,MAT2A,MX1,NFYA,ZNF426,NECAB2,POLR2F,C19orf57,MAPK7,ANKHD1,RBBP8,KHDRBS2,ZMAT4,RPE,MCMBP,KCNIP3,S100B,PUF60,CCDC92,FAM214B,GKAP1,ABTB1,RCOR3,DBNDD2,CAMTA2,EXOC7,TRIM2,ARHGAP9,FAM124A,SSBP2,HSPBP1,UBC,EIF4ENIF1,SH3GLB2,PRTFDC1,FIP1L1,PLSCR4,DOCK8,RTN4" Pubmed 20436479 A genomic atlas of mouse hypothalamic development. Pubmed 1.53E-10 2.65E-05 2.11E-07 2.66E-06 41 195 "TMCC3,SEMA6A,NCOA1,ZNF445,SLIT2,LHX2,CNTFR,IGDCC3,NECTIN3,CRYM,SIPA1L1,DLX1,FEM1B,EMX2,ERBB2,ADGRV1,FGFR1,GAD1,NTNG2,GNAO1,FAM107A,INSM1,LSAMP,NEXMIF,NOVA1,NTRK3,OPRL1,MAGEL2,EPDR1,RASGRF1,ROBO1,RORB,SEMA6D,ARX,SOX11,BHLHB9,SSBP2,WNT7A,ZIC2,FZD3,SPATA13" Pubmed 16537572 Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Pubmed 1.56E-10 2.72E-05 2.14E-07 2.70E-06 42 203 "APAF1,CHRD,BMP7,BMPR1B,CALB1,SLC25A14,NOG,CNR1,PICK1,COL9A1,COL11A2,HAPLN1,VCAN,DGKG,SPOCK2,SPOCK3,NR1D2,RACK1,FGFR1,FGFR3,BAIAP2,CSPG5,DLL3,SYT17,PACSIN2,MATN2,MATN3,NCAM2,PAX6,SEMA5B,PKD1,RELN,LAMA1,PTH1R,CRTAC1,BAALC,S100B,HKDC1,THSD1,STX1A,NPDC1,TFIP11" Pubmed 19274049 "A census of human transcription factors: function, expression and evolution." Pubmed 1.70E-10 2.95E-05 2.30E-07 2.91E-06 116 908 "LCORL,ARNTL,NCOA1,BACH1,JAZF1,MYRF,ZBED1,FOXN3,LHX2,VAX2,AHCTF1,ZNF385A,CLOCK,CREM,HINFP,ELMSAN1,ZBTB24,ZC3H11A,DLX1,NR1D2,DMTF1,E2F5,E2F6,EBF1,HEYL,EGR3,EMX2,ETV1,EZH1,FOXF2,FOXO3,ZBED3,ZNF44,ZNF274,GLI2,TOX3,PRDM5,SOX21,ATOH8,TOX2,ZHX1,BACH2,MIER3,HLF,HNF4G,HSF2,IRF8,ZNF181,RBPJ,INSM1,SMAD1,SMAD9,MEF2C,MEIS1,MEIS2,MITF,MXI1,MYCN,MYT1,NFE2L2,NFIX,NFYA,PAX6,POU6F1,IRX1,PPARA,SKOR1,ZSCAN2,DPF2,RFX2,RFX3,ZFHX4,RORB,RXRA,SALL1,SATB1,ARX,PKNOX2,RCOR3,TRERF1,SOX3,SOX11,SOX15,ZHX3,SP2,SP4,CAMTA2,MESP1,CAMTA1,TAL1,TCF4,SATB2,CUX2,ZEB1,TCF12,HIF3A,ZFPM2,THRA,HEY1,NR2E1,NR2C2,TRPS1,UBTF,ZBTB14,ZIC1,ZIC2,ZNF711,ZNF708,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZBTB38,MEIS3,ZNF30" Pubmed 21307259 LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. Pubmed 1.90E-10 3.30E-05 2.56E-07 3.23E-06 11 15 "AP2A1,AP2A2,CADPS,CLTC,SNAP91,DNM1,LRRK2,STX1B,SYN1,SYP,SYT1" Pubmed 10574462 Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 2.00E-10 3.47E-05 2.67E-07 3.37E-06 28 102 "NDRG2,TMCC3,PLEKHH1,USP31,KIAA1211,RNF150,ESYT2,LRFN2,MTA3,ZNF608,INTS2,MTUS1,CCPG1,GDA,KIF26A,ANKFY1,DENND2A,ZDHHC8,KANSL1,CCDC88A,OGDHL,BDP1,ERBIN,SULF2,SYNE1,FSTL5,PRDM10,ADAMTSL3" Pubmed 16985003 Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Pubmed 2.25E-10 3.91E-05 2.99E-07 3.77E-06 33 137 "KCNH8,KCNAB2,ATP2A2,HCN2,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,P2RX6,KCNAB3,CACNA2D2,CLCN3,KCNMB4,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNN1,KCNN3,KCNQ3,P2RX7,KCNIP3,KCNIP1,SCN7A,SCN8A,SLC8A1,KCNK12,KCNAB1" Pubmed 23515096 Maturation of postnatally generated olfactory bulb granule cells depends on functional ?-protocadherin expression. Pubmed 2.37E-10 4.13E-05 3.13E-07 3.95E-06 13 22 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2" Pubmed 25979088 Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Pubmed 2.44E-10 4.25E-05 3.19E-07 4.04E-06 18 44 "CACNA1A,CAMK2B,CLCN3,TUBB3,GABRA3,GABRG2,GAD1,GRIA2,GRIN2D,GRM2,GRM8,KCNB1,KCNH2,KCNQ3,RELN,SCN8A,STX1A,KCNAB1" Pubmed 24448406 The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Pubmed 2.60E-10 4.53E-05 3.38E-07 4.27E-06 14 26 "CASK,PTBP2,CAMK2A,CAMK2B,MAGI1,DBN1,DNM1,GPHN,ERBB4,GABRG2,GRIA2,PPP3CA,NLGN1,SYP" Pubmed 22360420 "Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration." Pubmed 2.96E-10 5.15E-05 3.82E-07 4.83E-06 27 97 "SYN3,AP2A1,AP2A2,AMPH,CALB2,CAMK2A,CBR1,VCAN,SCRN1,ENO2,SIRPB1,HSPA12B,ATP6V1H,NEGR1,PSAT1,PPP3CA,PPP3CC,PRPH,PRRT2,STX1B,MYH15,SPTB,STX1A,STXBP1,SYT1,TUBB2A,TUBB1" Pubmed 15741177 Tagging genes with cassette-exchange sites. Pubmed 3.10E-10 5.39E-05 3.97E-07 5.01E-06 54 308 "ZFAT,MAP4K3,CARS,ARHGEF2,SEPT7,ZMYM4,PLAA,COL11A2,RBM39,NCOR1,NCOR2,PUM1,HDAC4,DDX46,EIF4G1,SEPT9,MALT1,GLI2,STMN2,DIDO1,PRDM5,CIT,KAT7,MAT2A,MKLN1,AFDN,ZNF655,PLEC,PPP2R5E,PRKACB,MAPK3,QRICH1,PTK2,ENOX1,SAFB,SCAF8,DHX30,TET1,ZNF423,ARHGAP26,CLASP2,PRRC2C,MMS19,SMG6,DOCK9,PUM2,SIRT1,TNS1,NPL,ZNF346,TOM1L2,SMARCAD1,CIAPIN1,SOCS4" Pubmed 19030180 Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. Pubmed 4.45E-10 7.73E-05 5.64E-07 7.13E-06 31 126 "NRP2,LHX2,ZNF521,CRYM,TIAM2,DLX1,EBF1,EGR3,EMX2,ERBB4,ETV1,GAD1,GNAL,GUCY1A1,MAP2,MEF2C,MEIS2,NTRK2,PAX6,POU6F1,ROBO1,ROBO2,RORB,ARX,SOX11,TCF4,CUX2,HEY1,NR2E1,ZIC1,SLC17A7" Pubmed 11853319 Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. Pubmed 5.27E-10 9.16E-05 6.64E-07 8.39E-06 19 51 "UNC5A,CCAR2,DIS3L,FAM171B,EARS2,YTHDC1,GRIN3A,ADGRV1,KIAA1958,C2CD4C,SH3TC2,ATP8B4,SGSM1,FNIP1,ZFP90,ANKRD24,ZNF17,AMZ1,RSPRY1" Pubmed 11879655 Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Pubmed 5.86E-10 1.02E-04 7.33E-07 9.26E-06 8 8 "AP2A1,AP2A2,AMPH,BIN1,SYNJ1,CLTC,DNM1,SYP" Pubmed 19892785 Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon. Pubmed 6.13E-10 1.07E-04 7.62E-07 9.63E-06 10 13 "CALB1,CALB2,CCK,MBP,NF1,STX1B,SNAP25,SST,STX1A,RTN4" Pubmed 26071364 The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Pubmed 7.53E-10 1.31E-04 9.29E-07 1.17E-05 15 32 "AXIN2,BMP7,CALB1,CALB2,SLIT2,TUBB3,GAD1,L1CAM,MAP2,MAPT,NFIX,PAX6,RFX3,SATB2,RPGRIP1L" Pubmed 18519826 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Pubmed 8.00E-10 1.39E-04 9.80E-07 1.24E-05 27 101 "MTUS1,ADGRF5,TMEM108,LARGE1,MAGI1,CHN2,NRXN3,ERC2,DAPK1,DPP6,FGF12,ST6GALNAC3,LUZP2,PTPRT,KCNN3,NECAB2,PPP2R2B,LAMA1,PTPRD,NEK11,SNAP25,ZNF423,CLSTN2,TEK,CSMD1,TRIO,BCL2L13" Pubmed 16107646 Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Pubmed 8.27E-10 1.44E-04 1.01E-06 1.27E-05 34 151 "NCKAP5,FMNL2,LRCH2,DCLK1,QKI,CNN3,MATR3,FAM107B,CDON,DNM1L,FEM1B,PHF20L1,MEX3B,GABRG2,TOX3,ZNF638,SOX21,PSIP1,SMAD1,MEST,KITLG,POC1B,PCDH18,PBRM1,PCMTD2,TRA2B,WDR37,ATF7IP,SOX11,THSD1,ERBIN,SIRT1,TMPO,TP53BP1" Pubmed 28378742 Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Pubmed 8.83E-10 1.54E-04 1.07E-06 1.35E-05 174 1577 "ACTN1,FMNL2,ADD1,ESYT2,SORCS2,OSBPL8,FGD2,ATP1A1,EIF4G3,ATP2A2,MYOM1,DOCK11,NRP2,FUBP1,HIP1R,CBLN1,ARHGEF1,SYNGR3,ENTPD6,ARHGEF2,LRRFIP1,CLGN,COPB2,PLAA,MYL6B,CLTC,QKI,COL11A2,MAGED1,AHCTF1,NRG2,RBM39,AKAP12,CRMP1,ANKRD44,SEC24C,PUM1,CYBB,DCAF8,MATR3,INTS1,DBN1,DBT,MYEF2,ELMO1,POM121,DNM1,DOCK2,DPYSL2,DNAJB6,FIS1,GOLT1B,EEF1D,EGFR,SRPK3,STARD3NL,MFSD10,SPEG,ADGRV1,HSPA12B,TUBA1B,PTK2B,TUBB3,RACK1,PRMT5,ATP5PD,SYNCRIP,RGPD5,FLNC,ANKFY1,NOP56,SMC2,FAM49B,ATP6V1H,MPP6,GAA,IQGAP2,ERAP1,SEPT9,TUBA8,AHDC1,COPS8,SPIN1,GLYR1,CBX1,GNAO1,GP1BB,GPD2,STMN2,C1QL4,GSN,MAN1B1,NCKAP1L,ATXN2L,HMGCL,HMGCR,HP,IDH3B,IFI16,KIF5A,IPO5,MAT2A,MEST,MOV10,DBNL,MYH3,MYO5A,HNRNPM,NCF2,NPR2,PALM,PCDHGC3,PFKFB3,FAM98B,PKM,NLE1,PLEC,PCDH18,PLTP,PPM1B,PRKACB,PRKAR1B,PRKCB,PRPH,PSMA6,PTH1R,RNH1,EXD2,KLHDC8A,KIRREL1,PCMTD2,RPL15,RPS20,SAFB,SEMA6D,TRA2B,PUF60,MYO18A,HKDC1,SEC31A,DHX30,SEPHS1,SMARCA4,TTC17,RBM34,BDP1,GLT8D1,SPTAN1,TROVE2,SUPT5H,DNAJC9,MMS19,TCF12,PUM2,ARL10,TMPO,TUBB2A,SGK3,TUBB1,RPL7L1,UBE3A,UBTF,FLRT2,BCL2L13,VAV1,XPO1,TUBA1A,SIGLEC10,ITM2C,UBE3B,AAAS,FXR1,AP3B2,LAS1L" Pubmed 20935630 "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Pubmed 9.20E-10 1.60E-04 1.10E-06 1.39E-05 20 58 "ZNF608,CCDC146,STK33,PTBP2,NRXN3,IQCK,SH2B1,DNAJC27,CELF1,CBX1,ATXN2L,HMGCR,HNF4G,NEGR1,LRP1B,KCTD15,SKOR1,FAIM2,ZC3H4,CADM2" Pubmed 18617019 Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei. Pubmed 9.47E-10 1.65E-04 1.13E-06 1.43E-05 14 28 "SEMA6A,SEMA7A,NRP2,SLIT2,PLXNA4,SEMA3D,PLXNC1,SEMA4D,SEMA5B,PLXNB1,ROBO1,ROBO2,SEMA6D,SEMA3B" Pubmed 19723784 "Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses." Pubmed 1.04E-09 1.81E-04 1.23E-06 1.55E-05 13 24 "LRBA,DNM1,GPHN,NBEA,CPLX2,STX1B,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYP,SLC17A7" Pubmed 24698270 "Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity." Pubmed 1.04E-09 1.81E-04 1.23E-06 1.55E-05 13 24 "PCDHGC3,PCDHGB7,PCDHGB2,PCDHGA10,PCDHB15,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 22863883 A high-throughput approach for measuring temporal changes in the interactome. Pubmed 1.09E-09 1.89E-04 1.27E-06 1.61E-05 163 1456 "ABCF1,ACADM,ACTN1,MTA3,AMPD2,BIN1,OGT,CCAR2,DYNLL1,ALDH7A1,FUBP1,NAE1,MTMR2,AP1M1,CAST,CARS,SPAG9,CBS,ARHGEF1,LRBA,SEPT7,LRRFIP1,COPB2,EPS15L1,PLAA,HECTD1,AKAP12,CRMP1,GDA,CS,SEC24C,ARHGEF10,APPL1,CTH,GAPVD1,DCAF8,IST1,SCRN1,SEC16A,DNM1,DPYSL2,PDCD6IP,TOM1,FARSB,DNM1L,EEF1D,OPTN,EIF4G1,EIF5,COPS4,DCTN4,ENO2,EPB41L2,GPHN,RRAGB,GMPR2,TUBB3,RACK1,PRMT5,SEC23B,SYNCRIP,FLNC,ANKFY1,DCTN2,SMC2,UFM1,PDLIM5,STAMBP,TRIM16,ATP6V1H,OGA,ARFIP1,WASHC2A,USP19,COPS8,GLUL,HTATSF1,FERMT2,PRUNE2,ATE1,PACSIN2,DDX19B,ACOT7,AGFG1,HSPA1L,IPO5,KTN1,LAMP2,NCOA7,MAP2,MAP4,MAT2A,GIT1,DBNL,NACA,HNRNPM,NUCB2,PDE3A,PDE4D,OLA1,PKM,PLEC,STRN3,PSAT1,PPP2R5E,PPP3CA,PPP5C,PRKACB,PRKAR1B,PRPSAP2,PSMA6,QRICH1,SPDL1,RIPOR1,USP47,RAP1GDS1,OXR1,RDX,UBR7,RNH1,ELP2,RPL15,MCMBP,RPS20,CLIP1,SARS,COPZ1,HSPA4L,PUF60,KIF21A,SHMT2,PPP4R3A,ARFGAP1,INTS9,LIMCH1,SNCA,KIF13A,PEG10,SPTAN1,TROVE2,NSFL1C,JMJD6,SUPT5H,ANKRD28,MMS19,DNMBP,TCEA1,FRYL,SIRT1,TPM1,TPM2,TSN,HSPBP1,TUBB2A,UBE2H,UBE3A,TBC1D15,KLC2,XPO1,SH3GLB2,SMARCAD1,TUBA1A,CIAPIN1" Pubmed 12690205 Human chromosome 7: DNA sequence and biology. Pubmed 1.21E-09 2.11E-04 1.40E-06 1.77E-05 77 536 "ATP6V0E2-AS1,ACHE,ESYT2,AMPH,AZGP1,GPR146,CASTOR3,JAZF1,GPC2,CAMK2B,ISPD,KRIT1,DGKI,AP4M1,TBRG4,ASIC3,CHN2,C7orf61,OSBPL3,CNTNAP2,PLXNA4,PNPLA8,DGKB,ELMO1,TMEM130,NYAP1,DYNC1I1,DNAJB6,SEMA3D,AASS,LINC-PINT,STARD3NL,ETV1,PRKAG2,AGAP3,SLC37A3,TPK1,MPP6,GCK,GPER1,GPR37,PCLO,KCND2,KCNH2,MEST,MKLN1,COL28A1,DBNL,NPY,NPTX2,ABCB1,ZNF655,SNX10,PILRA,CEP41,EPDR1,RELN,SAMD9,PTN,GAL3ST4,ZDHHC4,SUGCT,SMARCD3,HECW1,SYPL1,TAF6,GALNT17,RUNDC3B,ZKSCAN5,UBE2H,LINC00689,CCDC136,VIPR2,AGMO,AMZ1,ST7,PRRT4" Pubmed 11114734 The protein tyrosine kinase family of the human genome. Pubmed 1.21E-09 2.11E-04 1.40E-06 1.77E-05 24 83 "ALK,BTK,DDR1,AATK,CSF1R,EGFR,TNK2,EPHB1,ERBB2,ERBB4,PTK2B,FER,FGFR1,FGFR3,FLT1,FYN,JAK2,KIT,MATK,NTRK2,NTRK3,PTK2,RET,TEK" Pubmed 27565344 Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Pubmed 1.29E-09 2.25E-04 1.48E-06 1.87E-05 15 33 "ADD1,SGCE,DCTN1,GPHN,EVL,DCLK2,KIF2A,PAX6,CLIP1,KIF21A,ELMO2,CLASP2,SYNE2,CLASP1,CLIP2" Pubmed 19056867 Large-scale proteomics and phosphoproteomics of urinary exosomes. Pubmed 1.47E-09 2.56E-04 1.67E-06 2.12E-05 123 1017 "ACTN1,NDRG3,OSBPL1A,TAOK1,ALCAM,BBOX1,ALK,CDC42BPA,APAF1,CPNE5,SHROOM2,ARHGDIA,ARSE,SLC4A4,ATP6V0A1,PROM1,AP1M1,C5,RAB29,CA4,CACNA2D1,CALB1,KALRN,SPAG9,CBR1,AP4M1,SLIT2,TPP1,CLTC,AHCTF1,CDC42BPB,CRYM,CST3,APPL1,CTH,IST1,AIF1L,TIAM2,RUSC2,PDCD6IP,TOM1,GOLGA7,PLEKHA1,ENPP6,ADGRV1,ACSL4,RACK1,BAIAP2,PCYOX1,IQCG,ANKFY1,DCTN2,SMC2,FAM49B,STAMBP,ATP6V1H,SDCBP2,GAA,IQGAP2,ALDH1L1,COPS8,GLUL,GPD1,GSN,PADI2,PACSIN2,DDX19B,ACOT7,HNMT,HP,SCIN,GATD1,KHK,KIFC3,LAMP2,GPR155,DBNL,MYH3,MYO6,DNHD1,PDCD2,OLA1,ABCB1,DUSP26,PIK3C2A,PKD1,TMEM38A,PKM,PLCD1,PSAT1,SLC26A11,VPS13C,CNTLN,PTPN13,EML5,PTPRO,RIPOR1,QDPR,RAP1GDS1,RDX,RNH1,GSTCD,ROBO2,LRRK2,FUZ,SHMT2,CNKSR2,SLC2A5,CDK5RAP2,MBD5,PBLD,STXBP1,SYPL1,MGRN1,CUX2,SLC44A1,BHLHB9,STXBP4,TUBB2A,TOM1L2,CRB2,TUBA1A,ITM2C" Pubmed 11163262 Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Pubmed 1.82E-09 3.16E-04 2.05E-06 2.60E-05 9 11 "CALB1,CALB2,DLX1,TUBB3,GAD1,MAP2,NPY,RELN,SST" Pubmed 15604093 Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Pubmed 1.85E-09 3.22E-04 2.08E-06 2.63E-05 31 133 "ACTN1,NCOA1,KIF1A,CAMK2B,RGN,RNF14,NCOR1,NCOR2,DCTN1,NR1D2,EEF1D,FOXO3,PCDH17,PPARGC1A,GLUL,GSN,CLASRP,GABARAPL2,HNF4G,MAP4,MAP6,NPY,NUCB2,NECAB2,ING3,RORB,RXRA,SHMT2,ITGB3BP,THRA,NR2C2" Pubmed 26460568 Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. Pubmed 1.95E-09 3.38E-04 2.17E-06 2.74E-05 38 187 "MAP4K3,APBB2,DST,ARHGEF1,RTTN,DMD,CELSR3,TUBA1B,TUBB3,RACK1,PRMT5,TUBA8,SPIN1,HSPA1L,KIFC3,HNRNPM,NEFM,NEFH,DNHD1,SEMA5B,PKD1,PLEC,PRPH,MYO18A,ANKRD36,SNRPN,ZC3H13,SPTAN1,SPTB,PHLDB1,SYNE2,PLCB1,CLASP1,SYNE1,WIPF1,TUBA1A,DNAH10,GAN" Pubmed 12853948 The DNA sequence of human chromosome 7. Pubmed 1.97E-09 3.42E-04 2.18E-06 2.75E-05 68 454 "ACHE,FZD9,AMPH,CDK13,AZGP1,SGCE,CACNA2D1,CAMK2B,KRIT1,CHN2,SUMF2,OSBPL3,CNTNAP2,PLXNA4,FAM131B,DOCK4,HDAC9,DGKB,SCRN1,GSDME,POM121,DYNC1I1,DPP6,DNAJB6,FIS1,SEMA3D,EGFR,RASA4,AASS,ELN,STARD3NL,LRRC17,ETV1,PRKAG2,MPP6,DBF4,GPR37,PCLO,GRB10,SCIN,KCND2,KCNH2,ADAM22,NPY,NPTX2,NRCAM,PDE1C,GPR85,ABCB1,ZNF655,SNX10,ING3,RELN,SAMD9,SUGCT,RADIL,SMARCD3,SP4,PEG10,STX1A,KLHL7,SYPL1,ZKSCAN5,UBE2H,CLIP2,LAT2,ST7,ACTR3B" Pubmed 15033168 Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. Pubmed 2.07E-09 3.59E-04 2.28E-06 2.88E-05 24 85 "ABR,PHF12,ATP2B2,FUBP1,B4GALT6,TAOK2,CLTB,SIPA1L1,SHANK1,PHC2,ERBB4,DLL3,CPLX1,RUNDC3A,PRRC2B,PTPRT,IGFBPL1,MYO5A,NFIX,ROBO1,FAIM2,SYT1,DICER1,ICAM5" Pubmed 25231870 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Pubmed 2.28E-09 3.96E-04 2.49E-06 3.15E-05 33 149 "ASPHD1,CCDC85A,BEND6,ARNTL,DST,EVI5L,DLGAP1,EIF4G1,GHR,BRD8,NEGR1,NCOA7,LRP1B,NTRK2,IGSF11,PCSK1,MAGEL2,WDR25,BDNF-AS,PTPRD,PTPRN2,PEX2,RMI1,GALNT10,TRA2B,KDM4C,WSCD1,SATB2,CRTC1,CSMD1,STXBP4,MKRN3,SMARCAD1" Pubmed 22884324 Functional significance of isoform diversification in the protocadherin gamma gene cluster. Pubmed 2.31E-09 4.02E-04 2.51E-06 3.18E-05 16 39 "PCDHGB4,CALB1,PAX6,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SLC17A7" Pubmed 20195357 A comprehensive resource of interacting protein regions for refining human transcription factor networks. Pubmed 2.66E-09 4.62E-04 2.87E-06 3.63E-05 38 189 "ANK2,KIF1A,CACNA1B,SRSF11,CHGB,STOML1,CABP1,NCOR2,ERC2,KIAA0408,MATR3,DCTN1,EEF1D,OPTN,COPS4,TUBA1B,TAOK3,KHDRBS3,MPP6,GABBR1,TCERG1,CBX1,MAP2,TCEAL5,NEFM,PKM,SCHIP1,PKIA,CYBC1,RGS3,RYR3,ZC3H13,SYT1,TAF9,TP53BP1,UBTF,ZNF24,TUBA1A" Pubmed 7829101 Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Pubmed 2.68E-09 4.66E-04 2.88E-06 3.64E-05 24 86 "ACTN1,DYNLL1,QKI,COL9A1,PREPL,PDCD6IP,KATNAL1,EYA1,FGF12,STXBP5,HECTD2,NEFM,PDE4D,PTN,FBXW7,SATB1,ATXN7,TNFRSF19,EPC1,NMNAT2,GLT8D1,ZNF423,TEK,REEP1" Pubmed 24613359 Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Pubmed 2.86E-09 4.97E-04 3.05E-06 3.86E-05 18 50 "ADGRB1,ADGRB2,ADGRB3,SLITRK5,GPHN,GAD1,LRRTM1,NTRK2,NTRK3,LRRN3,NLGN1,CLSTN2,SYN1,SYP,ADGRL3,LRRC24,FLRT2,SLC17A7" Pubmed 18614564 Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Pubmed 2.89E-09 5.03E-04 3.07E-06 3.88E-05 34 158 "AP2A1,CASKIN1,KCNAB2,BCAS1,DYNLL1,ATP6V0A1,CAMK2A,CAMK2B,CLTC,CNTN1,EPB41L2,TUBB3,ATP5PD,AGAP2,DCTN2,BRSK1,GLUL,GNAO1,TPPP,LSAMP,MAP2,MAP4,MAP6,MARK1,MYO5A,TMOD2,NDUFS7,SNCA,SPTAN1,STX1A,STXBP1,SYP,ICAM5,KCNAB1" Pubmed 19386638 Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Pubmed 3.77E-09 6.55E-04 3.97E-06 5.02E-05 29 122 "NRP2,LHX2,MAGED1,ZNF521,CRYM,TIAM2,DLX1,EBF1,EGR3,EMX2,ERBB4,ETV1,FOXO3,GAD1,GUCY1A1,MEF2C,MEIS2,PAX6,POU6F1,ROBO2,RORB,ARX,SOX11,TCF4,CUX2,HEY1,NR2E1,TP53BP1,ZIC1" Pubmed 15231748 Functional proteomics mapping of a human signaling pathway. Pubmed 4.18E-09 7.26E-04 4.38E-06 5.53E-05 81 591 "FMNL2,AP2A1,AP2A2,SPARCL1,CASK,ARRB2,CDK13,STX16,DST,THSD7A,LDB2,SUMF2,RNF14,NCOR1,NCOR2,TRIM69,PDE4DIP,PHACTR3,PUM1,RUBCN,ZFYVE16,DCTN1,DMTF1,PDCD6IP,TOM1,HIPK3,HEYL,OPTN,EBI3,EIF4G1,EIF4G2,FLNC,NELFCD,GLUL,HTATSF1,SMAD1,SMAD9,MBD1,AFF1,AFDN,MYO6,PKD1,PLEC,PPP2R5E,KANSL1,QRICH1,MTMR10,RBBP6,MORC4,RGS3,PBRM1,FAM161B,RXRA,ZFP2,EPN2,DHX30,LIMS2,SLC12A4,ATF7IP,ABTB1,KIF13A,MYCBP2,PEG10,SPART,ERBIN,ST5,STAU1,KANK1,SUPT5H,ANKRD28,ARHGAP9,ZNF106,HEY1,TP53BP2,TPM2,TTC3,UBC,UBE3A,GORASP1,TOM1L2,DOCK8" Pubmed 15164053 DNA sequence and analysis of human chromosome 9. Pubmed 6.12E-09 1.06E-03 6.37E-06 8.05E-05 58 371 "MPDZ,IL33,KYAT1,PLAA,FAM189A2,BRINP1,AIF1L,SEC16A,ECM2,FSD1L,RABEPK,FKTN,SEMA4D,TMEM8B,FREM1,SPIN1,KIAA1958,PRRC2B,PRUNE2,PLPP7,SPACA9,ADAMTS13,CACFD1,SLC2A6,MAN1B1,JAK2,NPR2,DIRAS2,APTX,CNTLN,PTCH1,RFX3,RGS3,RORB,RMI1,FAM102A,CDK5RAP2,FAM219A,FNBP1,KDM4C,SPTAN1,KANK1,VPS13A,PHF24,SLC44A1,NACC2,LRRC8A,CDK20,TPM2,C9orf85,ANKRD20A2,VLDLR,CRB2,ZNF189,SH3GLB2,ZFAND5,URM1,DOCK8" Pubmed 10862698 Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Pubmed 6.63E-09 1.15E-03 6.86E-06 8.67E-05 23 83 "CAMK2A,CAMK2B,CDH2,DLGAP1,CLTC,AKAP5,APPL1,DNM1,PTK2B,GRIN2D,CIT,MAP2,NF1,PIK3R1,PPP3CA,PPP5C,PRKCB,MAPK3,SPTAN1,ARC,TP53BP1,KLC2,TUBA1A" Pubmed 11780052 The DNA sequence and comparative analysis of human chromosome 20. Pubmed 6.82E-09 1.19E-03 7.02E-06 8.87E-05 73 517 "EMILIN3,NDRG3,ADRA1D,MYH7B,BCAS1,STX16,BMP7,NFS1,CBFA2T2,ENTPD6,CDC25B,CHGB,CHRNA4,COL9A3,RBM39,MROH8,RIMS4,PHACTR3,CST3,PPP1R16B,SNPH,ZNF337,RASSF2,TM9SF4,SPATA2,ACOT8,EDN3,SIRPB1,HSPA12B,SEC23B,NOP56,NELFCD,ERGIC3,SDCBP2,ACSS1,GGT7,DIDO1,PTPRT,TOX2,DHX35,IDH3B,MYLK2,INSM1,KCNB1,MYT1,NNAT,OPRL1,SMOX,PLTP,NKAIN4,VSTM2L,FITM2,DUSP15,TSPY26P,PCMTD2,KIF16B,BTBD3,ZNF334,NAPB,ELMO2,ARFGAP1,SNAP25,DOK5,ZHX3,DBNDD2,STAU1,SULF2,NSFL1C,PLCB1,CDH22,TUBB1,LAMP5,FAM182B" Pubmed 15146195 Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Pubmed 8.36E-09 1.45E-03 8.55E-06 1.08E-04 16 42 "SPARCL1,APLP1,ATP1A1,ATP1A3,ATP2B2,ADAM23,CNTN1,DNM1,DPP6,DPYSL2,APH1A,L1CAM,LSAMP,MBP,NCAM2,STXBP1" Pubmed 7913715 Organization of the embryonic and early postnatal murine hippocampus. I. Immunocytochemical characterization of neuronal populations in the subplate and marginal zone. Pubmed 8.44E-09 1.47E-03 8.59E-06 1.09E-04 7 7 "CALB1,CALB2,CCK,MAP2,NPY,SNAP25,SST" Pubmed 19240061 Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Pubmed 8.54E-09 1.49E-03 8.63E-06 1.09E-04 46 265 "BBOX1,DNAH17,ADGRB3,CACNA2D1,P2RX6,LONRF2,ABI3BP,ANKRD44,GREB1,YAF2,ERBB4,EYA1,DLC1,AK8,KIAA1841,FAM19A2,TOX2,RBPJ,IL6ST,KCNJ16,MEIS1,MMP16,MN1,NPY,ZNF827,PDE1C,PDE4B,IRX1,PTPN13,PTPRD,SH3TC2,MSANTD2,FIGN,ROBO2,STK32B,SLA,SLC12A2,MYCBP2,PLCB1,COBL,GALNT17,R3HDM1,CSMD1,PARD3,TNS1,CELF4" Pubmed 15142957 Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Pubmed 8.79E-09 1.53E-03 8.84E-06 1.12E-04 20 65 "OSBPL1A,SEMA7A,CACNA2D1,CRLF1,NGEF,CRYM,RASGRP2,NEGR1,SOWAHA,LSAMP,MEF2C,MMP17,FXYD7,NPY,PAX6,SLC8A1,LIMCH1,SST,TST,VSNL1" Pubmed 16632597 Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Pubmed 1.05E-08 1.82E-03 1.05E-05 1.32E-04 17 48 "CDH2,CRMP1,DLX1,ETV1,TUBB3,FGF13,STMN2,L1CAM,MAPT,TAGLN3,GNG2,SERPINI1,MAPK10,PRPH,RET,PCDHA1,UCHL1" Pubmed 16033648 A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Pubmed 1.12E-08 1.94E-03 1.11E-05 1.40E-04 48 285 "TNRC6C,SYNJ2,FUBP1,PTBP2,SRSF11,QKI,RBM39,PUM1,PABPC5,MYEF2,KLHL3,ALKBH8,CPEB2,POLR1B,SYNCRIP,KHDRBS3,STAU2,PPARGC1A,RNPS1,TNRC6A,ZNF638,HTATSF1,TDRKH,CELF5,MSI1,HNRNPM,CNOT4,NOVA1,NOVA2,PCBP3,ANKHD1,KHDRBS2,SAFB,TRA2B,SCAF8,DHX30,SLC6A8,CPEB4,RBM34,PEG10,RBM26,STAU1,PUM2,CELF4,TFIP11,PCBP4,NELFE,FXR1" Pubmed 20211142 An atlas of combinatorial transcriptional regulation in mouse and man. Pubmed 1.17E-08 2.03E-03 1.15E-05 1.46E-04 104 846 "KDM5D,BIN1,APC,ARNTL,ZSCAN18,BACH1,BARD1,RUNX1T1,LDB2,CERS5,CBFA2T2,CNOT8,LHX2,VAX2,FHL5,TBPL1,ZFP28,RBM39,RNF14,NCOR2,PHF14,PYGO1,HDAC9,HDAC4,MAML1,ZBTB24,DLX1,EBF1,HEYL,SUGP2,ASB3,ING4,EMX2,DENND4A,POLR1B,ZNF274,CSDC2,PPARGC1A,ZNF276,RNPS1,TOX3,KDM2B,PRDM5,ZNF496,HLF,HNF4G,ZDHHC15,ZNF546,LMO2,SMAD1,MBD1,MEF2C,MEIS1,MEIS2,MITF,ZNF92,MXI1,MYCN,NFE2L2,NFYA,PAX6,POU6F1,PPARA,ZSCAN32,ZSCAN2,DPF2,RFX2,RFX3,CARF,RORB,KCNIP3,RXRA,HES6,ZFP2,ZFP30,ANKRD6,PKNOX2,SIRT2,ABTB1,KDM4B,SOX15,SP2,KDM4C,ZBTB43,SUPT5H,MMS19,TAL1,TBL1X,TCF4,TCF12,SIRT1,THRA,TRPS1,SSBP2,ZKSCAN5,UBTF,ZIC1,ZIC2,ZNF23,ZNF24,ZNF70,ZNF184,ZNF195,MEIS3" Pubmed 11347906 Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.18E-08 2.05E-03 1.16E-05 1.46E-04 26 106 "TMEM132B,EP400,CDK13,MARK4,MSANTD4,HHIPL1,DOT1L,BRSK1,ABLIM2,NEURL4,ZMAT1,MEGF11,MEGF10,FAM120B,SRRM4,ACSS1,KIAA1841,NTNG2,TTBK1,MAP6,CHAMP1,HYDIN,RADIL,ELMO2,CCDC136,SH3GLB2" Pubmed 22681889 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Pubmed 1.40E-08 2.43E-03 1.36E-05 1.72E-04 100 806 "ABCF1,CDK13,CCAR2,EIF4G3,FUBP1,PTBP2,TBRG4,SRSF11,CLTC,QKI,BAG4,ZNF385A,RBM39,CS,CSNK1E,PUM1,MATR3,YTHDC1,MYEF2,ZC3H11A,DDX46,DNM1,CPEB2,SUGP2,MBNL2,EIF4G2,EIF5,EIF1,SRRM1,MRPL10,RACK1,MEX3B,SYNCRIP,NOP56,KHDRBS3,CELF1,STAU2,TCERG1,RNPS1,TNRC6A,ZNF638,PRRC2B,DIDO1,PSIP1,ATXN2L,IBA57,IPO5,MAP4,MBNL1,SRSF12,MOV10,MSI1,MYO5A,HNRNPM,CNOT4,NOVA1,NOVA2,FAM98B,XRN1,PURG,EXOSC10,ANKHD1,RBBP6,RADX,RPL15,ZC3H14,RPS20,NCBP3,SAFB,ATXN2,CASC3,TRA2B,PUF60,CPEB3,MYO18A,DHX30,CPEB4,RBM34,PEG10,ZC3H13,RBM26,LARP4,STAU1,ZC3H4,SUPT5H,PRRC2C,PCDHGA9,SYNE1,PUM2,R3HDM1,ZNF346,UBC,RPL7L1,EIF4ENIF1,UBTF,PCDH20,FIP1L1,HNRNPA3,FXR1,LAS1L" Pubmed 24305805 Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. Pubmed 1.41E-08 2.46E-03 1.37E-05 1.74E-04 10 16 "AP2A1,AP2A2,AMPH,SNAP91,PARD6A,CELSR3,EPHB1,L1CAM,MAPK9,FZD3" Pubmed 19029045 A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster. Pubmed 1.50E-08 2.61E-03 1.45E-05 1.83E-04 17 49 "PCDHGB4,CALB1,LHX2,GPHN,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SLC17A7" Pubmed 17124501 Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. Pubmed 1.54E-08 2.67E-03 1.47E-05 1.86E-04 12 24 "CASK,ERC2,RIMS2,SV2B,CPLX2,SNAP25,ERC1,STX1A,STXBP1,SYP,SYT1,RIMBP2" Pubmed 25241761 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. Pubmed 1.55E-08 2.70E-03 1.48E-05 1.87E-04 57 371 "ACTN1,APC,ARRB2,NUMB,BID,CFLAR,CAMK2A,CAMK2G,RUNX1T1,CD86,TAOK2,CLTC,ARHGEF6,CSF1R,CSF2RA,CSNK1E,APPL1,DAPK1,DOCK2,DUSP9,EGFR,ERBB2,F8,PTK2B,FCGR1A,FCGR3A,STRADA,FGF1,FGFR1,FOXO3,FLT1,FYN,GHR,HSPA1L,KIT,SMAD1,KITLG,NTRK2,PDPK1,PIK3R1,PKM,PPM1B,PRKCB,MAPK3,MAPK9,PTK2,RET,RPS6KA2,RXRA,MAPK12,SNCA,SPP1,FBXW11,TBL1X,PARD3,PIK3R5,RICTOR" Pubmed 18725516 Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Pubmed 1.57E-08 2.73E-03 1.49E-05 1.89E-04 20 67 "NDRG2,CARMIL3,AIF1L,EDNRB,NRN1,CLVS1,OLFM1,FGFR3,DLL3,INSM1,MYT1,PPP1R1A,LRRN3,RASGEF1B,HES6,ARX,SYBU,SOX11,SSTR2,MGAT5B" Pubmed 15229646 Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. Pubmed 1.68E-08 2.93E-03 1.59E-05 2.01E-04 11 20 "LHX2,DLX1,EMX2,ETV1,GAD1,GRIA2,PAX6,ROBO1,RORB,NR2E1,SLC17A7" Pubmed 17979178 A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes. Pubmed 1.77E-08 3.08E-03 1.66E-05 2.10E-04 23 87 "SHROOM2,KSR1,OSBPL3,HDAC4,DENND4A,BAIAP2,FOXO3,RASSF8,MARK3,AFDN,CDK18,PFKFB2,CLASP2,CLASP1,CRTC1,TIAM1,PARD3,TP53BP2,TSC1,TSC2,KLC2,REEP1,TUBA1A" Pubmed 10997877 Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.84E-08 3.19E-03 1.72E-05 2.17E-04 25 101 "EPB41L5,VAT1L,TNRC6C,USP37,CPNE5,SFMBT2,SEMA4G,PRX,PPP4R4,IGDCC4,SPTBN4,ZFYVE28,PLXNA4,MED12L,FLYWCH1,NBEA,MOV10,PCDH18,CCDC40,ZNF532,ROBO2,KIF16B,CDK5RAP2,ANKRD36,WNK3" Pubmed 17620599 Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Pubmed 1.89E-08 3.29E-03 1.76E-05 2.22E-04 51 317 "AP2A1,AP2A2,APLP1,ARRB1,ARRB2,CDK13,PTCH2,CALM1,CLTB,CLTC,CNGA3,ARHGEF6,ARHGAP32,KIF26A,DGKG,DBN1,DMD,DNM1,KCTD3,TUBB3,PRMT5,POLR1B,NOP56,TUBA8,SPIN1,HTATSF1,GSN,BACH2,HSPA1L,STXBP5,KTN1,LRP1B,AFDN,HNRNPM,PDE4D,PFKFB3,PIK3C2A,PKM,PPM1B,RGS3,RPL15,SPIN3,SPTAN1,MPRIP,TMPO,TUBB2A,UBC,TUBA1A,KCNAB1,HNRNPA3,AP3B2" Pubmed 22586326 Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Pubmed 1.97E-08 3.43E-03 1.82E-05 2.31E-04 85 653 "ABCF1,ACTN1,OSBPL8,ARHGDIA,CCAR2,ATP1A1,EIF4G3,ATP2A2,KIF1A,BLM,DST,SPAG9,COPB2,CLTC,HECTD1,AHCTF1,RBM39,SEC24C,PUM1,GAPVD1,INTS1,MYEF2,ZC3H11A,DDX46,SEC16A,MED12,DPYSL2,PDCD6IP,SUGP2,EIF4G1,EPB41L2,SRRM1,RACK1,PRMT5,SEC23B,SYNCRIP,FLNC,GLYR1,ZNF638,PRRC2B,DIDO1,ATXN2L,IPO5,MAP4,AFDN,MOV10,MYO5A,NEFM,NF1,XRN1,NLE1,PLEC,EXOSC10,ANKHD1,USP47,PBRM1,RNH1,RPL15,ZC3H14,SBF1,PUF60,DHX30,SMARCA4,SMARCC2,RBM34,ZSWIM8,MYCBP2,ZC3H13,SPTAN1,POGZ,LARP4,STAU1,SUPT5H,PRRC2C,SYNE2,ANKRD28,NSD1,FRYL,DICER1,TP53BP1,UBTF,XPO1,HNRNPA3,FXR1,LAS1L" Pubmed 11471062 High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Pubmed 2.25E-08 3.90E-03 2.07E-05 2.61E-04 18 56 "SYN3,NRP2,CHN1,CST3,MYEF2,EZH1,RASL10A,GAD1,INPP5K,GGT7,MCHR1,MAPT,PTPRN,ZFP2,SLA,SNAP25,PLCB1,ZNF142" Pubmed 16751776 A germline-specific class of small RNAs binds mammalian Piwi proteins. Pubmed 2.37E-08 4.13E-03 2.17E-05 2.75E-04 64 443 "ELFN2,ARHGAP20,MTMR3,CARS,HIP1R,USP6,LRWD1,COL9A1,COL9A3,AKAP12,SEC24C,APPL1,IP6K1,SV2B,SEC16A,EXOG,RPS6KL1,EIF4G2,TNK2,DNAJC27,PTK2B,ATP5PD,WDR83,SPECC1,STAMBP,DOT1L,NEU3,RNPS1,PRRC2B,DDX19B,FAM95B1,ZNF546,KNDC1,MBD1,LOC643201,XRRA1,FAM225B,PDPK1,POLG,RAD51D,ZDHHC4,RGS12,RPS6KA2,SBF1,CCDC92,CCDC88A,IFT122,ZHX3,SPTB,CDK19,MPRIP,TTBK2,SYN2,ANKRD12,USP22,CBX5,WBP2,NR2C2,CCDC136,TOM1L2,MARCH8,UBE3B,RNF170,IFT88" Pubmed 19906978 Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. Pubmed 2.41E-08 4.19E-03 2.19E-05 2.77E-04 33 163 "KCNH8,ALCAM,NRP2,SLIT2,RGS6,LRRC3B,KCTD8,DPP6,SEMA3D,PLXNC1,ETV1,TUBB3,FGF14,NTNG2,GRB10,SLC35G1,KCND2,LSAMP,PACRG,MSI1,SAMD14,NNAT,PCBP3,NECAB2,IRX1,PRPSAP2,ROBO1,ARMH4,KCNIP1,SCN8A,MYO16,TACR1,SPATA13" Pubmed 21368052 MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. Pubmed 2.98E-08 5.18E-03 2.70E-05 3.41E-04 17 51 "BMP7,CALB2,DLX1,ETV1,TUBB3,GAD1,L1CAM,MEF2C,MEIS2,MSI1,PAX6,POLG,RELN,RORB,ARX,SATB2,NR2E1" Pubmed 15461802 A genome annotation-driven approach to cloning the human ORFeome. Pubmed 3.06E-08 5.31E-03 2.75E-05 3.48E-04 48 294 "DGCR6,SYN3,ADORA2A,SLC2A11,BID,MTMR3,P2RX6,LARGE1,FBXO7,TMEM184B,SULT4A1,PICK1,GAL3ST1,CRYBB1,CSNK1E,SLC25A18,TOM1,TUBA8,CSDC2,GGT5,AIFM3,MCHR1,GSTT2,RABL2A,PACSIN2,LINC00634,MGAT3,MN1,ZDHHC8,POLR2F,PPARA,CASTOR1,TUG1,EMID1,MAPK12,PEX26,SEPT3,KIAA0930,RASD2,TST,HIRA,EIF4ENIF1,BCL2L13,ZNF70,ZNF74,POLR3H,TFIP11,HPS4" Pubmed 19075228 A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Pubmed 3.07E-08 5.34E-03 2.75E-05 3.48E-04 18 57 "ADGRF5,CASK,MYOM1,MTMR3,PTBP2,NCOR2,DTNA,MBNL2,FLNC,MPP6,ITGA7,MAP2,MBNL1,MEF2C,PPP3CA,CLIP1,R3HDM1,FXR1" Pubmed 19859539 Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. Pubmed 3.31E-08 5.76E-03 2.95E-05 3.73E-04 11 21 "CALB2,SLIT2,EPHB1,TUBB3,GAD1,L1CAM,MAP2,NPY,SNAP25,SATB2,SLC17A7" Pubmed 16273093 A quantitative protein interaction network for the ErbB receptors using protein microarrays. Pubmed 3.54E-08 6.15E-03 3.14E-05 3.97E-04 23 90 "APBB2,NUMB,NUMBL,CHN1,CHN2,SH2B1,APPL1,EGFR,ERBB2,ERBB4,FER,FGFR1,JAK2,MATK,SHC3,PIK3R1,SH3BP2,SLA,DOK5,TNS2,DOK6,VAV1,ANKS1B" Pubmed 24324551 Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. Pubmed 3.59E-08 6.23E-03 3.16E-05 4.00E-04 29 134 "SMIM29,ZFYVE28,KALRN,DLGAP1,SUMF2,RGS6,LRIG1,DOCK4,HDAC9,DGKB,DYNC1I1,FDFT1,CHL1,ALDH1L1,ALDH1L1-AS2,TJAP1,MITF,PTPRD,MRAS,SLC8A1,SPTB,CAMTA1,PMS2CL,TIAM1,ASXL3,CSMD1,RUNDC3B,EMX2OS,SMIM8" Pubmed 20096683 A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Pubmed 3.81E-08 6.62E-03 3.34E-05 4.23E-04 16 46 "ADORA2A,GUCD1,DLX1,ERBB4,ETV1,TUBB3,GAD1,GGT5,GSTT2,LSS,PAX6,S100B,ARX,SST,DIP2A,CABIN1" Pubmed 26871637 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Pubmed 5.25E-08 9.12E-03 4.58E-05 5.80E-04 80 615 "ACADM,ACTN1,NME5,GPRASP2,APBB2,APOC2,ARHGDIA,ARRB1,ATP2A2,BCS1L,ST3GAL5,SGCE,CAPN3,SCARB1,HOMER3,FHL5,SUMF2,MAGED1,CYBB,ZBTB24,KIAA0753,DMD,CD99L2,E2F6,OPTN,IRAK4,COPS4,DCTN4,RABEPK,SRRM1,ANKMY1,FCGR3A,FGFR1,AMOTL2,KHDRBS3,GAD1,SEPT9,ALDH1L1,GPD2,ZNF496,AGFG1,INPP1,ZFYVE27,MXI1,NCF2,NLGN3,SERPINI1,PPP3CA,MAPK7,SPDL1,ZCWPW1,ENOX1,BEND5,KHDRBS2,ALG9,MCMBP,ST6GALNAC6,S100B,ASAP3,SHMT2,PEX26,SP4,ARHGAP26,SPART,POGZ,ZC4H2,TRIM2,TNS2,TPM1,CDK20,SMUG1,GORASP1,BCL2L13,TRIM9,NDRG4,MKRN3,FTSJ1,TFIP11,PRTFDC1,DOCK8" Pubmed 19167335 Large-scale structural analysis of the classical human protein tyrosine phosphatome. Pubmed 5.40E-08 9.39E-03 4.69E-05 5.93E-04 16 47 "ALK,PKP4,CDH2,EGFR,TNK2,ERBB2,GHR,JAK2,KIT,PDPK1,MAPK3,PTPRB,PTPRE,PTPRG,PTPRO,TEK" Pubmed 19736351 "Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation." Pubmed 5.43E-08 9.43E-03 4.69E-05 5.93E-04 13 31 "DOC2A,DPP10,APBA2,CASK,DLGAP2,ERBB4,GABRB3,GABRG1,MAPT,PRODH,PTK2,NLGN1,ST7" Pubmed 21228161 Calcium channels link the muscle-derived synapse organizer laminin ?2 to Bassoon and CAST/Erc2 to organize presynaptic active zones. Pubmed 5.46E-08 9.49E-03 4.70E-05 5.94E-04 9 14 "CACNA1A,CACNA1B,ERC2,SV2B,PCLO,NEFH,ERC1,SYN1,SYP" Pubmed 17392456 Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. Pubmed 5.88E-08 1.02E-02 5.01E-05 6.33E-04 7 8 "CALB1,CALB2,SLIT2,L1CAM,NPY,ROBO1,ROBO2" Pubmed 10920050 Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Pubmed 5.88E-08 1.02E-02 5.01E-05 6.33E-04 7 8 "CALB1,CALB2,CCK,TUBB3,MAP2,NPY,SST" Pubmed 25875176 Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development. Pubmed 6.20E-08 1.08E-02 5.26E-05 6.65E-04 11 22 "NRP2,BMP7,CCK,ERBB4,ETV1,GAD1,CLDN11,RELN,RORB,SATB2,CUX2" Pubmed 16712791 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Pubmed 6.56E-08 1.14E-02 5.53E-05 7.00E-04 65 465 "ABR,CLK4,NDRG2,OLMALINC,KIAA1324,ALCAM,ATP1A3,AZGP1,BCS1L,CFLAR,HAP1,CCK,CDH2,PICK1,GALNT9,IP6K1,LYPD1,SUGP2,EGFR,CD320,F5,BAIAP2,IP6K2,WDR83,APOPT1,SDCBP2,GABRB3,MTHFD2,ARFIP1,AGBL5,HP,ZIC5,STXBP5,ZFYVE27,MBP,BLOC1S2,MX1,MYO9A,IDNK,NME4,PDE1C,ABCB1,TATDN3,PRKAB2,CEP41,MASP1,WBP1L,TUG1,RPS20,MAPK12,COPZ1,FUZ,KANSL3,EPC1,DMRTC1,SPP1,DBNDD2,PBLD,ADHFE1,PRRC2C,SYN2,SLC35G2,C9orf85,POLR3H,ZNF189" Pubmed 19243017 Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Pubmed 7.78E-08 1.35E-02 6.53E-05 8.26E-04 17 54 "SEMA6A,PROM1,RUNX1T1,PLXNA4,EBF1,HEYL,FRY,HSPA12B,AFDN,NF1,TMOD2,RGS3,SEMA6D,SEPT3,TUBB1,ZIC1,NDRG4" Pubmed 25838543 Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Pubmed 8.10E-08 1.41E-02 6.74E-05 8.52E-04 12 27 "AP2A1,SYNJ1,SLIT2,SHANK1,DCTN2,NBEA,RAPGEF6,SRRM4,ZFYVE27,PAX6,VPS13C,SATB2" Pubmed 20392955 Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. Pubmed 8.10E-08 1.41E-02 6.74E-05 8.52E-04 12 27 "CALB1,CALB2,TIAM2,DLX1,ERBB4,TUBB3,GAD1,GUCY1A1,MAP2,NPY,RELN,SST" Pubmed 27889896 Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice. Pubmed 9.96E-08 1.73E-02 8.25E-05 1.04E-03 24 102 "NDRG3,NDRG2,ADD1,PPFIA3,NUMB,SLC4A4,ATP2A2,WASF1,ENTPD2,ERC2,C2CD2L,DTNA,AGAP2,FERMT2,LNX1,GRIA2,KIF5A,PPP3CA,PRKAR1B,KLHL11,HSPA4L,ERC1,PHLDB1,TRIM9" Pubmed 22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Pubmed 1.05E-07 1.83E-02 8.68E-05 1.10E-03 17 55 "ADCY5,SFMBT2,MADD,FOXN3,AKAP6,CRY2,DGKB,CHL1,GCK,KDM2B,GRB10,IGF1,LYPLAL1,PCSK1,VPS13C,SYN2,DPYSL5" Pubmed 21194568 Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Pubmed 1.07E-07 1.85E-02 8.74E-05 1.11E-03 22 88 "BMPR1B,RUNX1T1,AHCTF1,ZNF521,DLX1,E2F5,E2F6,HEYL,MBNL2,NELFCD,GLI2,STMN2,MEIS2,NFIX,PAX6,ANKHD1,DPF2,HES6,ATF7IP,TAF9,NR2E1,TMPO" Pubmed 25281560 Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. Pubmed 1.08E-07 1.88E-02 8.80E-05 1.11E-03 81 636 "PWWP2A,AP2A1,ZNF608,ZNF687,EP400,PARG,ARRB2,BARD1,DST,ARHGEF7,WASF1,SPAG9,PRC1,LRBA,EPS15L1,ARHGEF6,FAM169A,DZIP3,ZFYVE16,GIT2,DBT,ZBTB24,KIAA0753,SEC16A,USP3,MED12,PHC2,EPB41,SRRM1,F5,KAT8,ATP5PD,NOP56,DCTN2,PDLIM5,ATP6V1H,C15orf41,SRCAP,BRD8,RNPS1,GLYR1,MSL3,ZNF638,GNAO1,KAT7,MSL1,RBPJ,KIF5A,GIT1,XRN1,DPF2,UBR7,KIF7,PBRM1,CCDC25,SCP2,SUPT20H,TRA2B,EPC1,KDM4B,MYCBP2,ERC1,SPTAN1,SPART,ERBIN,NSFL1C,DNAJC9,TCEA1,CBX5,ACTR6,CABIN1,TP53BP2,METTL3,HSPBP1,HIRA,CCDC14,XRCC4,ZNF711,SH3GLB2,TUBA1A,FIP1L1" Pubmed 11756498 Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. Pubmed 1.18E-07 2.04E-02 9.55E-05 1.21E-03 14 38 "ABR,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF9,MCF2L,TIAM1,VAV1" Pubmed 9195986 Identification and characterization of a nerve terminal-enriched amphiphysin isoform. Pubmed 1.22E-07 2.12E-02 9.84E-05 1.24E-03 6 6 "AP2A2,AMPH,BIN1,SYNJ1,CLTC,DNM1" Pubmed 17500595 Huntingtin interacting proteins are genetic modifiers of neurodegeneration. Pubmed 1.24E-07 2.15E-02 9.96E-05 1.26E-03 33 174 "CA4,CACNA2D1,SEPT7,TPP1,CLTC,CNTN1,NCOR1,ARHGAP24,DNM1,DPYSL2,EEF1D,OPTN,EPB41,RACK1,DCTN2,TCERG1,GNAO1,NEGR1,LSAMP,PIK3R1,PKM,JAKMIP1,DIRAS2,STX1B,SNAP25,SPTAN1,STX1A,STXBP1,SYN1,SYP,SYT1,TACC1,DNALI1" Pubmed 20562859 Network organization of the human autophagy system. Pubmed 1.24E-07 2.16E-02 9.96E-05 1.26E-03 61 433 "EMILIN3,ESYT2,OSBPL8,TAOK1,CCAR2,DYNLL1,ALDH7A1,CALM1,CBR1,COPB2,CLTC,CSNK1G3,DZIP3,RUBCN,RASSF2,PDCD6IP,FARSB,EIF5,CEP78,STRADA,SEC24B,PRKAG2,SEC23B,VTI1B,FOXO3,FLNC,ANKFY1,UFM1,CAMKK2,IQGAP2,SEPT9,FREM1,GABARAPL2,IDH3A,IPO5,NCOA7,MAP4,PTOV1,NEFM,PDPK1,PIK3C2A,PRKAB2,MCMBP,SAFB,SARS,FNIP1,SHMT2,AMBRA1,FNBP1,ERC1,RBM26,MLST8,OBSL1,TMPO,TP53BP2,TSC1,TBC1D15,XPO1,ZNF24,SH3GLB2,GAN" Pubmed 25631876 The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon. Pubmed 1.32E-07 2.30E-02 1.05E-04 1.33E-03 13 33 "SEMA6A,CALB2,LHX2,PLXNA4,EBF1,TUBB3,PAX6,SEMA5B,PTCH1,RFX3,ROBO1,ROBO2,SATB2" Pubmed 19851296 Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Pubmed 1.36E-07 2.37E-02 1.08E-04 1.37E-03 29 142 "SORCS2,BIN1,GAS7,USP37,SPTBN4,SLIT2,AKAP12,NCOR2,FAM13A,MEGF11,SEPT9,ACSS1,CPLX2,ALDH1L1,DIDO1,ACOT7,MAPKAP1,PIGG,PTPRN2,RGS12,SBF1,ZFP30,WDR37,OGDHL,CAMTA1,VIPR2,ITM2C,WNK2,JPH3" Pubmed 29055695 Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Pubmed 1.41E-07 2.46E-02 1.12E-04 1.41E-03 17 56 "OGT,PTBP2,SRSF11,ZNF521,RBM39,MATR3,MBNL2,SYNCRIP,MEIS2,NOVA1,PAX6,OLA1,STRN3,SETD5,TRA2B,TCF12,XPO1" Pubmed 23376485 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Pubmed 1.53E-07 2.66E-02 1.20E-04 1.51E-03 178 1744 "ACADM,ABHD6,NDRG2,GALNT16,AGT,TAOK1,SPARCL1,BBOX1,LTBP4,PI16,APOC1,APOC2,ARHGDIA,ASPA,DYNLL1,ATP1A1,SLC4A4,ALDH7A1,ATP6V0A1,AZGP1,BID,PROM1,DST,RAB29,CA4,DDR1,CACNA2D1,CALB1,THSD7A,CALM1,SPAG9,CBR1,ENTPD6,CDH2,ZNF445,SLIT2,PPT2,TPP1,CLTC,CNTN1,COX4I1,GDA,CRYM,CS,CSF1,CST3,ZSCAN23,MYADM,IST1,DBI,AIF1L,B3GAT3,DPP6,PDCD6IP,SNX29,GOLGA7,COPS4,PCOLCE2,EPB41L2,ENPP6,STX2,NCALD,SIRPB1,EXTL2,CD320,REEP2,ACSL4,TUBA1B,RACK1,ST3GAL6,FCGR3A,BAIAP2,ATP5PD,PCYOX1,UFM1,FAM49B,ATP6V1H,TPPP3,SDCBP2,GAA,GALC,IQGAP2,GATM,ALDH1L1,LYVE1,DHRS4,COPS8,GLUL,LILRB4,GPD1,BTN2A1,GSN,HBA1,PACSIN2,VSIG4,ZDHHC15,HP,NEGR1,GAREM2,SCIN,IL6ST,ITGAM,KHK,LAMA2,LAMP2,GPR155,MAP4,LYPLAL1,MYO6,NACA,BEX5,IGSF11,OCRL,CLDN11,PCDHGC3,GNG2,OLA1,ABCB1,SERPINI1,PKM,PLCD1,PLEC,TRHDE,PSAT1,POLG,PPP3CC,PRKACB,MAPK3,EPDR1,PSMA6,PTH1R,PTPN13,PTPRG,PTPRO,RIPOR1,QDPR,FAT4,RNASE1,RNH1,KIRREL1,CCDC25,EPHA10,RPL15,PTGR2,RPS20,SCP2,MRAS,KIF27,SH3GL3,FRMPD1,ST6GAL1,SLC2A5,CDK5RAP2,SPP1,NFASC,PBLD,APOM,PLCB1,SYPL1,PDLIM2,MGRN1,PCDHGC5,CLASP1,SZT2,TST,UBC,UCHL1,FLRT2,TOM1L2,TBC1D15,ZNF711,ELFN1,CRB2,SEMA3B,URM1,ITM2C,PLSCR4,RTN4" Pubmed 26687479 "The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis." Pubmed 1.53E-07 2.67E-02 1.20E-04 1.51E-03 57 396 "ABCF1,MTA3,AK2,SPOP,EP400,CCAR2,PRC1,CFL2,LETMD1,MAGED1,NCOR2,CS,EBF1,PHC2,TMTC1,YAF2,ING4,MRPL37,ARMCX1,PRAM1,TUBB3,SCML2,FECH,SPECC1,TUBGCP4,TXNL4A,TCERG1,KDM2B,PCLO,DIDO1,KAT7,SOX21,PSIP1,ZIC5,NACA,EXOSC10,PPP2R5E,NDUFS7,PBRM1,PCMTD2,RPE,CLIP1,SALL1,FBXO11,SMARCC2,TRERF1,ERC1,PEG10,STAU1,TBL1X,TCF4,SATB2,TP53BP1,TSC2,ZIC2,TUBA1A,MRPL47" Pubmed 24711643 Identifying biological pathways that underlie primordial short stature using network analysis. Pubmed 1.54E-07 2.67E-02 1.20E-04 1.51E-03 116 1024 "ABCF1,ACTN1,AP2A1,EP400,ARHGDIA,CCAR2,ATP1A1,ATP2A2,DST,FUBP1,CACNA2D1,CBR1,ARHGEF2,LRWD1,SRSF11,SLIT2,MYL6B,CLTC,MAP4K4,RBM39,CS,SEC24C,PUM1,GAPVD1,MATR3,INTS1,MYEF2,ZC3H11A,DDX46,POM121,SACS,SEC16A,PDCD6IP,EDIL3,EEF1D,SUGP2,EIF4G1,EPB41L2,SRRM1,F5,TUBA1B,RACK1,PRMT5,ATP5PD,SYNCRIP,FLNC,NOP56,SMC2,SPECC1,FYN,NEURL4,SEPT9,SRCAP,RNPS1,ZNF638,CBX1,GPD2,CIT,GSN,PSIP1,HBA1,IDH3A,IDH3B,SCIN,KIF2A,IPO5,MAP4,AFDN,MYO5A,NACA,NF1,OLA1,ABCB1,PKM,NLE1,PLEC,EXOSC10,KIF7,PBRM1,EXD2,RPL15,ZC3H14,NCBP3,SAFB,TRA2B,PUF60,SHMT2,DHX30,SLC12A2,SMARCA4,SMARCC2,MYCBP2,ITPRID2,STAU1,PHLDB1,ZC3H4,SUPT5H,SYNE2,SYNE1,OBSL1,DICER1,CBX5,TMPO,UBC,RPL7L1,UBTF,UCHL1,TBC1D15,XPO1,ZNF24,FIP1L1,ITM2C,HNRNPA3,AAAS,FXR1,LAS1L" Pubmed 20198315 Association of genetic variants with hemorrhagic stroke in Japanese individuals. Pubmed 1.60E-07 2.77E-02 1.24E-04 1.57E-03 29 143 "SORCS2,BIN1,GAS7,USP37,SPTBN4,SLIT2,AKAP12,NCOR2,FAM13A,MEGF11,SEPT9,ACSS1,CPLX2,ALDH1L1,DIDO1,ACOT7,MAPKAP1,PIGG,PTPRN2,RGS12,SBF1,ZFP30,WDR37,OGDHL,CAMTA1,VIPR2,ITM2C,WNK2,JPH3" Pubmed 29513653 Developmental diversification of cortical inhibitory interneurons. Pubmed 1.65E-07 2.88E-02 1.28E-04 1.62E-03 21 83 "PCDH10,RUNX1T1,LHX2,CST3,DBI,TIAM2,DLX1,EBF1,EDNRB,FGFR3,GAD1,CSDC2,SOX21,INSM1,MEF2C,MYT1,NNAT,PAX6,PBRM1,ARX,SOX11" Pubmed 22922362 Transcription factor Foxp3 and its protein partners form a complex regulatory network. Pubmed 1.66E-07 2.89E-02 1.28E-04 1.62E-03 53 358 "ADD1,AP2A1,CCAR2,EIF4G3,BCL7A,KRIT1,ARHGEF1,COPB2,QKI,CNN3,ARHGEF6,AHCTF1,SEC24C,SIPA1L1,GIT2,DBT,ELMSAN1,MYEF2,PDCD6IP,DNAJB6,DNM1L,PHC2,EIF4G1,ACSL4,RGPD5,SPECC1,FYB1,RNPS1,ZNF638,GSN,NCKAP1L,MSL1,LIMS1,MAP4,MBNL1,DBNL,PFKFB3,FAM98B,PLEC,DPF2,NCBP3,ATXN2,DHX30,SMARCA4,SMARCC2,RBM34,SP2,CLASP2,ZNF346,VAV1,TFIP11,INTS3,LAS1L" Pubmed 16221301 "Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events." Pubmed 1.93E-07 3.35E-02 1.48E-04 1.87E-03 11 24 "GPRASP2,GPRASP1,ARMCX4,ARMCX2,ARMCX1,TCEAL6,TCEAL5,BEX5,BHLHB9,BEX4,TCEAL7" Pubmed 15123239 An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies. Pubmed 2.06E-07 3.58E-02 1.57E-04 1.99E-03 21 84 "ABR,ACTN1,ADRA1D,APC,CASK,ATP2B2,ADGRB2,ADGRB3,ARHGEF7,MTMR2,GDA,FOXO3,GRIN2C,ADAMTS6,MAP4,MPP2,MAPK12,SSTR1,ERBIN,NR2E1,VIPR2" Pubmed 16701205 A role for Nr-CAM in the patterning of binocular visual pathways. Pubmed 2.08E-07 3.62E-02 1.57E-04 1.99E-03 8 12 "CNTN1,EPHB1,CHL1,L1CAM,NRCAM,CNTN3,NFASC,ZIC2" Pubmed 29056747 PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Pubmed 2.08E-07 3.62E-02 1.57E-04 1.99E-03 8 12 "SYS1,MAP2,PRRT2,SNAP25,STX1A,SYN1,SYN2,SYP" Pubmed 20889312 A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. Pubmed 2.23E-07 3.87E-02 1.68E-04 2.12E-03 18 64 "NCKAP5,VAT1L,BCAS1,CACNA2D1,CRYBB1,CNTNAP2,DMD,ADAMTS6,CELF5,FAM69A,COL28A1,NALCN,VPS13C,RFX2,FAM81A,KDM4C,ASTN2,SMARCAD1" Pubmed 7553862 Complexins: cytosolic proteins that regulate SNAP receptor function. Pubmed 2.48E-07 4.32E-02 1.86E-04 2.35E-03 7 9 "CPLX2,CPLX1,SNAP25,STX1A,STXBP1,SYP,SYT1" Pubmed 19328558 Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Pubmed 2.67E-07 4.64E-02 1.99E-04 2.52E-03 16 52 "SORCS2,ARNTL,CAMK2A,CLOCK,DPYSL2,PDLIM5,GAD1,DISC1,GNAL,GRIK4,CIT,P2RX7,KIF13A,SST,CUX2,MPPE1" Pubmed 17913789 Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Pubmed 2.74E-07 4.77E-02 2.04E-04 2.58E-03 9 16 "CALB1,CALB2,ETV1,GAD1,NEFH,RELN,RORB,CUX2,VLDLR" Pubmed 20811636 "The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1." Pubmed 2.75E-07 4.79E-02 2.04E-04 2.58E-03 35 197 "RALGAPA1,ACTN1,AP2A2,ARHGAP20,CDK13,DST,CCNT1,SRSF11,TBPL1,RASGEF1C,SEC16A,DMD,DOCK2,AASS,F5,PRMT5,SEC24B,CLASRP,ATXN2L,IDH3A,PAXBP1,MARK3,NEXMIF,NME4,KCTD15,REV3L,SNX22,HSPA4L,ZC3H13,SPTAN1,SYNE2,SYNE1,TBC1D15,TFIP11,DHX33" Pubmed 29576527 "Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability." Pubmed 2.95E-07 5.14E-02 2.18E-04 2.75E-03 29 147 "USP31,USP35,USP37,BLM,USP6,USP2,SMARCAL1,USP3,DTNB,VPS26C,USP19,DHRS4,NF1,MINDY2,USP47,KIF7,USP33,FNBP1,ZSWIM8,MLST8,AGTPBP1,DMXL2,RPGRIP1L,USP22,SZT2,FRYL,UBC,UCHL1,RICTOR" Pubmed 21862448 Gene expression analysis of the embryonic subplate. Pubmed 2.98E-07 5.19E-02 2.19E-04 2.77E-03 13 35 "ZNF521,PLXNA4,SV2B,RCAN2,GAD1,KIT,MYO9A,RELN,RASGRF1,RORB,SEMA6D,SLC8A1,KCNT2" Pubmed 20881960 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Pubmed 3.12E-07 5.43E-02 2.28E-04 2.89E-03 35 198 "SYN3,NCKAP5,CASKIN1,ZFAT,LCORL,JAZF1,NOG,SOCS5,ZBTB24,STARD3NL,DNAJC27,FER,FOLH1,DOT1L,ADAM28,SPIN1,FAM69A,KCNJ16,LYPLAL1,MEF2C,GIT1,MYO9A,NUCB2,PCSK5,SMOX,PTCH1,PEX2,ADAMTS17,FAM208A,FBXW11,TNS1,ZNF142,ZBTB38,ADAMTSL3,ADAMTS10" Pubmed 23535033 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Pubmed 3.57E-07 6.21E-02 2.60E-04 3.29E-03 16 53 "ARHGAP20,VAT1L,CACNA1G,SLC4A8,ELMO1,MRPL10,MEGF10,AFF1,BCAS3,STK32B,LIMS2,MYO16,HECW1,NKAIN2,PRRC2C,CSMD1" Pubmed 23667531 The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. Pubmed 4.17E-07 7.24E-02 3.02E-04 3.82E-03 44 282 "MTA3,INTS2,ZNF687,EP400,ZBTB10,CCAR2,CCNT1,ARMC8,CLOCK,NCOR1,INTS1,MYEF2,SEC16A,DNAJB6,DNM1L,PHC2,SUGP2,TUBB3,AMOTL2,SMC2,WASHC2A,BRD8,MSL3,FERMT2,MSL1,IPO5,MEIS2,MKLN1,OLA1,ZFHX4,RNH1,CHD9,INTS9,TRERF1,SP2,SUPT5H,MMS19,SMG6,SIN3B,TCF12,TUBB2A,INTS3,TUBA1A,LAS1L" Pubmed 12787561 Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR). Pubmed 4.28E-07 7.43E-02 3.09E-04 3.90E-03 17 60 "ABR,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF4,TIAM2,APH1A,RASGRF1,RASGRF2,ARHGEF9,ITGB3BP,TIAM1,UBC,VAV1" Pubmed 25971728 Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2. Pubmed 4.50E-07 7.83E-02 3.24E-04 4.09E-03 10 21 "LHX2,EMX2,ETV1,TUBB3,NEFH,PAX6,RORB,STX1A,SATB2,CUX2" Pubmed 20634891 Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Pubmed 4.79E-07 8.32E-02 3.42E-04 4.33E-03 49 331 "ACTN1,C1QTNF3,AMT,APOC2,MARK4,PTCH2,BMPR1B,CBS,CDH2,FOXN3,CHRNA4,COL11A2,NECTIN3,CTH,DLX1,EDN1,EGFR,EGR3,EMX2,ERCC2,PIPOX,EYA1,FGF1,FGF12,FGFR1,FGFR3,FOXF2,FOLH1,FOLR2,POMT1,CHL1,GABRB3,GAD1,MTHFD2,ALDH1L1,GDF1,GLI2,SMAD1,MAT2A,OGG1,ABCB1,PTCH1,RET,SALL1,SPP1,SATB2,CUX2,TRPS1,ZNF189" Pubmed 15383276 "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease." Pubmed 4.95E-07 8.60E-02 3.53E-04 4.46E-03 19 74 "CEP126,GPRASP2,APLP1,BARD1,HAP1,CLTC,CRMP1,ARMCX2,DNM1L,GDF9,TCERG1,KAT7,FICD,ZHX1,GIT1,PTN,SH3GL3,TAL1,DNALI1" Pubmed 21706016 Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. Pubmed 4.98E-07 8.66E-02 3.53E-04 4.47E-03 23 103 "MAP4K3,SYNJ1,ARHGEF7,EPS15L1,DOCK4,DNM1,EGFR,STAMBP,MAP4K5,GAREM2,TTYH2,PIK3AP1,AFDN,GIT1,PIK3R1,PPP5C,RBBP6,KIRREL1,HUNK,RADIL,ELMO2,CLASP2,WIPF1" Pubmed 17883393 Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains. Pubmed 5.06E-07 8.79E-02 3.53E-04 4.47E-03 12 31 "ST3GAL5,B4GALT6,GAL3ST1,FUT9,GALC,B4GALNT1,NEU3,MAP2,ST6GALNAC6,ST8SIA1,NEU4,UGT8" Pubmed 18854036 Loss of transforming growth factor-beta 2 leads to impairment of central synapse function. Pubmed 5.08E-07 8.83E-02 3.53E-04 4.47E-03 8 13 "GPHN,NLGN3,S100B,NLGN1,SYN1,SYN2,SYP,SLC17A7" Pubmed 15145078 Quantification of synapse formation and maintenance in vivo in the absence of synaptic release. Pubmed 5.08E-07 8.83E-02 3.53E-04 4.47E-03 8 13 "DOC2A,GRIA2,MAPT,STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 18260139 Sall3 is required for the terminal maturation of olfactory glomerular interneurons. Pubmed 5.08E-07 8.83E-02 3.53E-04 4.47E-03 8 13 "CALB1,CALB2,ETV1,TUBB3,GAD1,PAX6,RELN,SALL1" Pubmed 19332558 The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Pubmed 5.08E-07 8.83E-02 3.53E-04 4.47E-03 8 13 "NRP2,CALB1,CALB2,CELSR3,ERBB4,TUBB3,MAP2,SST" Pubmed 22689450 Regulation of archicortical arealization by the transcription factor Zbtb20. Pubmed 5.23E-07 9.10E-02 3.63E-04 4.58E-03 11 26 "NRP2,CALB2,LHX2,EMX2,EPHB1,ETV1,GRIK4,INSM1,KITLG,PAX6,SATB2" Pubmed 20410112 Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. Pubmed 5.47E-07 9.50E-02 3.74E-04 4.73E-03 9 17 "CALB1,CALB2,TUBB3,FGFR1,GAD1,PAX6,RELN,SST,SATB2" Pubmed 15570159 "CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity." Pubmed 5.47E-07 9.50E-02 3.74E-04 4.73E-03 9 17 "L1CAM,RELN,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 22542597 The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Pubmed 5.47E-07 9.50E-02 3.74E-04 4.73E-03 9 17 "APC,CSF1,CSF1R,TUBB3,MBP,PAX6,S100B,SATB2,IL34" Pubmed 26795843 LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Pubmed 6.31E-07 1.10E-01 4.30E-04 5.44E-03 13 37 "SYN3,SYT13,CALB2,LHX2,DLX1,EMX2,TUBB3,STMN2,MAP2,MAPT,PTCH1,SST,SATB2" Pubmed 14574404 The DNA sequence and analysis of human chromosome 6. Pubmed 6.39E-07 1.11E-01 4.34E-04 5.48E-03 77 621 "ABCF1,LRFN2,HACE1,FGD2,C6orf89,DDO,CPNE5,ATP6V1G2,RIPK1,DST,SYNJ2,DDR1,PPT2,QKI,LY86,FHL5,CNR1,AKAP7,COL9A1,COL11A2,TBPL1,ZSCAN23,KIAA0408,ZBTB24,KIAA0319,SNAP91,EDN1,RGS17,NRN1,SYNCRIP,FOXO3,FUT9,FYN,GABBR1,TRAF3IP2,TTBK1,BTN2A1,BACH2,ELOVL5,HSF2,HSPA1L,SMAP1,TJAP1,STXBP5,NCOA7,PACRG,AFDN,MYO6,NFYA,PDCD2,ZDHHC14,REV3L,MRPS18A,MRAP2,RPS6KA2,SCAF8,SGK1,ANKRD6,ZKSCAN3,KIF13A,LMBRD1,TRERF1,CDK19,NKAIN2,ELOVL4,APOM,SYNE1,NR2E1,PPIL6,DCBLD1,TUBB2A,RPL7L1,MTCH1,NELFE,PDSS2,SMIM8,RNF146" Pubmed 19946888 Defining the membrane proteome of NK cells. Pubmed 6.43E-07 1.12E-01 4.35E-04 5.50E-03 126 1168 "ABCF1,ABR,ESYT2,AP2A1,INTS2,OSBPL8,C1QTNF3,DYNLL1,CHID1,KSR1,AP1M1,CAMK2G,LRBA,EPS15L1,CLCN3,CLTC,COX4I1,NCOR1,NCOR2,OSBPL3,MATR3,INTS1,DCTN1,ELMO1,B3GAT3,MED12,DOCK2,PDCD6IP,DNAJB6,FARSB,DNM1L,FIS1,GOLT1B,APH1A,PLXNC1,EIF4G1,EIF4G2,TNK2,STARD3NL,CD320,F5,ACSL4,AGAP2,SYNCRIP,EVL,NOP56,NELFCD,ATP2C1,ERGIC3,CELF1,STAU2,OGA,GAA,GHDC,ERAP1,INPP5K,TUBGCP4,CNTRL,CIT,HBA1,MAN1B1,NCKAP1L,DDX19B,ATXN2L,ELOVL5,IFI16,IL6ST,KIF2A,KIF5A,IPO5,KTN1,LSS,MIA2,GIT1,MYO5A,MYO6,HNRNPM,NF1,SLC11A2,OPA1,OLA1,PIK3C2A,PIK3R1,XRN1,EXOSC10,MBOAT7,CEP41,PRPH,GDPD1,PIGG,PEX2,ALG9,RPS20,ATXN2,SCP2,MYO18A,FNDC3A,CDK5RAP3,SMARCA4,IFT122,LMBRD1,KDM3A,GLT8D1,MYCBP2,CLASP2,LARP4,STAU1,PRRC2C,MMS19,EXOC7,ALG1,MGRN1,CLASP1,DOCK9,SLC44A1,LRRC8A,TMPO,EIF4ENIF1,KLC2,XPO1,TMEM237,DOCK8,ZDHHC20,AAAS,FXR1,LAS1L" Pubmed 20471030 Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Pubmed 6.76E-07 1.18E-01 4.56E-04 5.76E-03 15 49 "SYN3,ANK2,CBR1,FHL5,GDA,CRYM,GLUL,MAPT,MBP,NEFM,PLEC,QDPR,STX1A,STXBP1,SYT5" Pubmed 12376548 "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway." Pubmed 6.84E-07 1.19E-01 4.59E-04 5.81E-03 14 43 "ABR,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF9,TIAM1,VAV1" Pubmed 16147992 Analysis of BCL6-interacting proteins by tandem mass spectrometry. Pubmed 7.15E-07 1.24E-01 4.78E-04 6.04E-03 17 62 "OSBPL1A,WDR35,CACNA1A,NCOR1,NCOR2,HDAC9,HDAC4,DNAH9,EBF1,PPARGC1A,LPAR4,PCDH9,OLA1,SMARCA4,CSMD1,EIF4ENIF1,SENP7" Pubmed 27432908 Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Pubmed 7.26E-07 1.26E-01 4.84E-04 6.11E-03 105 931 "AP2A2,HECW2,CASKIN1,CDC14B,STX16,DOCK11,MTMR3,MTMR2,RAB29,CBS,MTMR7,CDC25B,CLGN,DIS3L,RAB28,TPP1,QKI,CNN3,ARMC8,COX4I1,CDC42BPB,GAPVD1,DCAF8,DCTN1,B3GAT3,MTX3,DMD,ACOT8,DTNA,DTNB,DUSP9,KCTD3,COPS4,DCTN4,FDFT1,POLR1B,PCYOX1,VTI1B,DCTN2,COQ5,MTHFD2,NFU1,DHRS4,COPS8,SPIN1,CBX1,ATE1,MAN1B1,ACOT7,GATD1,KIF2A,KPNA5,IPO5,KCTD6,DBNL,PDE4D,DUSP26,PPP2R2B,PPP5C,MAPK3,MAPK4,MAPK9,CNNM2,CYBC1,MTMR10,PTPRE,PTPRN,PTPRO,RAP1GDS1,OXR1,ELP2,AP1AR,SARS,SBF1,COPZ1,HSPA4L,AMBRA1,FBXO11,PPP4R3A,RBM34,GLT8D1,ZBTB43,TROVE2,SUPT5H,NUDT10,ALG1,FBXW11,MGRN1,TNS2,SIRT1,ZFPM2,ARL10,MTMR14,TMEM9,TNS1,STXBP4,HSPBP1,RPL7L1,UGT8,MTCH1,TBC1D15,XPO1,XRCC4,MFF,MRPL47" Pubmed 12351730 Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. Pubmed 7.42E-07 1.29E-01 4.85E-04 6.13E-03 6 7 "ACHE,CALB2,TUBB3,MAP2,NEFH,FZD3" Pubmed 9280305 Clathrin interacts specifically with amphiphysin and is displaced by dynamin. Pubmed 7.42E-07 1.29E-01 4.85E-04 6.13E-03 6 7 "AP2A1,AP2A2,AMPH,BIN1,CLTC,DNM1" Pubmed 7671305 "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein." Pubmed 7.42E-07 1.29E-01 4.85E-04 6.13E-03 6 7 "AP2A1,AP2A2,STX1A,SYN1,SYP,AP3B2" Pubmed 22404429 "Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons." Pubmed 7.42E-07 1.29E-01 4.85E-04 6.13E-03 6 7 "DBN1,TUBB3,PRPH,STX1B,STX1A,RUSC1" Pubmed 22337885 TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis. Pubmed 7.42E-07 1.29E-01 4.85E-04 6.13E-03 6 7 "PLPPR4,PTGR2,PLPPR3,TRIM67,UBC,TRIM9" Pubmed 20029029 Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Pubmed 7.54E-07 1.31E-01 4.89E-04 6.19E-03 20 83 "SPARCL1,CALM1,CBR1,COL9A3,AKAP12,MATR3,RUSC2,EGFR,ERBB2,ERBB4,OLFM1,DCTN2,GABARAPL2,PPP5C,PRKAR1B,RAP1GDS1,MAST1,TPM1,UCHL1,MAP3K12" Pubmed 21491433 "Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala." Pubmed 7.54E-07 1.31E-01 4.89E-04 6.19E-03 20 83 "RASL11B,BAIAP3,CALB1,VXN,NECTIN3,GREB1,SEMA3D,ETV1,GAD1,KIT,PDE1C,MAGEL2,RELN,RFX3,RORB,SST,ASTN2,CHST8,SLC30A3,SPATA13" Pubmed 28386764 Roles of tau protein in health and disease. Pubmed 7.74E-07 1.35E-01 4.97E-04 6.28E-03 10 22 "TAOK1,MARK4,FYN,TTBK1,MAPT,MARK1,MARK3,PPP5C,TTBK2,SIRT1" Pubmed 27466336 "Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons." Pubmed 7.77E-07 1.35E-01 4.97E-04 6.28E-03 7 10 "CPLX2,CPLX1,STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 11804571 Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Pubmed 7.77E-07 1.35E-01 4.97E-04 6.28E-03 7 10 "CALB1,CALB2,SLIT2,NEFH,NPY,ROBO1,ROBO2" Pubmed 11074448 Evidence for intrinsic development of olfactory structures in Pax-6 mutant mice. Pubmed 7.77E-07 1.35E-01 4.97E-04 6.28E-03 7 10 "NRP2,CALB1,CALB2,EMX2,PAX6,ROBO2,SEMA3B" Pubmed 22745667 Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. Pubmed 8.21E-07 1.43E-01 5.23E-04 6.61E-03 16 56 "AMPH,BTK,ARHGEF4,RUSC2,DOCK2,SH3YL1,MPP6,FYN,MIA2,MYO7A,PIK3R1,SH3KBP1,ARHGEF9,DNMBP,VAV1,SPATA13" Pubmed 21658586 Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors. Pubmed 8.28E-07 1.44E-01 5.25E-04 6.64E-03 11 27 "NRP2,CALB1,CALB2,DLX1,ETV1,GAD1,NPY,PTCH1,ARX,SST,ZIC1" Pubmed 26930384 "Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun." Pubmed 9.03E-07 1.57E-01 5.70E-04 7.20E-03 26 130 "EMILIN3,ADCY5,MYOM1,AKAP6,AKAP12,CRMP1,LRIG1,BOC,MYADM,NCALD,MRVI1,FOXF2,ACOT7,NKD1,MAPT,MEF2C,NELL2,NF1,PSD,PTN,KCNIP1,SLC8A1,FNBP1,ZNF423,TAL1,FZD3" Pubmed 23754746 Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Pubmed 9.04E-07 1.57E-01 5.70E-04 7.20E-03 15 50 "C1QTNF3,RAB33A,CSF2RA,ZDHHC15,OCRL,MAGEL2,SH3KBP1,SLC6A8,SNRPN,PCDHB15,PCDHB4,PCDHB3,PCDHA6,PCDHA1,MKRN3" Pubmed 25277244 The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Pubmed 9.25E-07 1.61E-01 5.81E-04 7.34E-03 37 225 "ACTN1,ZFAT,EIF4G3,ARHGEF7,CLCN3,HECTD1,RBM39,GAPVD1,LONRF1,OPTN,KCTD3,EIF4G2,EIF5,EPB41L2,CEP78,AGAP3,INPP5K,NFU1,SPIN1,CBX1,BVES,MSL1,RBPJ,ENPP2,KANSL1,PSMA6,PPP2R3C,SBF1,CDK5RAP3,SMARCA4,SPATA7,TSNAXIP1,SUPT5H,OBSL1,TTC3,XPO1,FXR1" Pubmed 19799774 Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Pubmed 9.59E-07 1.67E-01 6.00E-04 7.58E-03 18 70 "CAMK2A,CHGB,IPCEF1,CYBB,PPP1R1B,UBE2E3,GSTM5,HBA1,MAPT,MBP,SEPT4,PPP3CA,RGS4,ROBO1,RORB,FAM81A,SOX11,KIAA0930" Pubmed 12799088 Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Pubmed 1.03E-06 1.78E-01 6.34E-04 8.02E-03 9 18 "ARHGEF7,ARHGEF25,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,MCF2L,DNMBP,SPATA13" Pubmed 21508241 Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain. Pubmed 1.03E-06 1.78E-01 6.34E-04 8.02E-03 9 18 "NRP2,CALB1,SLIT2,PPP1R1B,FLT1,GAD1,ROBO1,ROBO2,SST" Pubmed 12588844 BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Pubmed 1.03E-06 1.78E-01 6.34E-04 8.02E-03 9 18 "CALB1,CALB2,GAD1,GRIA2,RELN,STX1B,STX1A,SYN1,SYP" Pubmed 22103416 Differential gene expression in migratory streams of cortical interneurons. Pubmed 1.11E-06 1.93E-01 6.83E-04 8.63E-03 8 14 "CNR1,NRN1,GAD1,RASGEF1B,RELN,PTPRO,PLCB1,FLRT2" Pubmed 16615895 Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Pubmed 1.11E-06 1.93E-01 6.83E-04 8.63E-03 8 14 "CALB1,CALB2,EBF1,ERBB4,TUBB3,GAD1,L1CAM,MEIS2" Pubmed 25977363 Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo. Pubmed 1.12E-06 1.94E-01 6.83E-04 8.63E-03 12 33 "AXIN2,PCDH19,PCDH10,CHRD,NOG,PCDH17,PCDH8,PCDH9,PCDH18,MESP1,TCF4,PCDH20" Pubmed 16829211 Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Pubmed 1.17E-06 2.03E-01 7.11E-04 8.99E-03 17 64 "NRP2,CDH2,CDO1,PCOLCE2,CGREF1,GSN,MEF2C,SNX10,PLTP,PTCH1,PTH1R,PTPN13,SMPD3,RASA3,SPP1,UNC5B,SATB2" Pubmed 21725061 CIN85 interacting proteins in B cells-specific role for SHIP-1. Pubmed 1.20E-06 2.08E-01 7.29E-04 9.21E-03 15 51 "AP2A1,AP2A2,HIP1R,SEPT7,CLTC,DBT,PDCD6IP,SEPT9,IDH3B,PIK3AP1,PIK3R1,SH3KBP1,SPTAN1,UBTF,WIPF1" Pubmed 19531213 Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. Pubmed 1.21E-06 2.10E-01 7.32E-04 9.25E-03 23 108 "SYNJ1,SYNJ2,PRC1,SEPT7,ELMSAN1,POM121,DNM1,PDCD6IP,KCTD3,SRRM1,SEPT9,TUBGCP4,PSIP1,SYNPO,MAP4,SH3KBP1,ATXN2,SH3BP2,LIMCH1,ERC1,SEPT8,PHLDB1,WIPF1" Pubmed 15815621 Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Pubmed 1.22E-06 2.12E-01 7.35E-04 9.30E-03 59 442 "GALNT13,ADD1,ADD2,RNF150,CCDC74A,KIF1A,BARD1,ST3GAL5,LRRFIP1,CHN1,NDST3,NGEF,CNGA3,CNRIP1,DBI,YTHDC1,E2F6,KLHL5,SPEG,POLR1B,UBE2E3,RGPD5,STAMBP,MTHFD2,SULT1C4,MMADHC,GPR75,ZNF638,RABL2A,HNMT,AGFG1,C2orf72,SFXN5,LIMS1,ASPRV1,GPR155,MAT2A,FIGN,CARF,KCNIP3,AP1AR,CSRNP3,HES6,HSPA4L,ANKRD36,KDM3A,ITPRID2,CEP68,NEU4,CLASP1,SLC19A3,PUM2,FAM200B,TSN,XPO1,REEP1,TMEM237,RNF103,HNRNPA3" Pubmed 20301682 Hereditary Spastic Paraplegia Overview Pubmed 1.26E-06 2.19E-01 7.59E-04 9.59E-03 13 39 "KIF1A,AP4M1,AP4B1,GAD1,AP4S1,KIF5A,L1CAM,ZFYVE27,FA2H,SPART,AP4E1,REEP1,GJC2" Pubmed 17470284 Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. Pubmed 1.28E-06 2.22E-01 7.59E-04 9.60E-03 11 28 "LHX2,DLX1,EMX2,ETV1,TUBB3,GAD1,PAX6,RELN,ROBO1,RORB,CUX2" Pubmed 21826226 Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. Pubmed 1.28E-06 2.23E-01 7.59E-04 9.60E-03 10 23 "NUMB,PROM1,CALB2,EMX2,ERBB2,TUBB3,MSI1,PAX6,RELN,DICER1" Pubmed 24487590 TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. Pubmed 1.28E-06 2.23E-01 7.59E-04 9.60E-03 10 23 "CALB1,CALB2,HAP1,GAD1,GNG4,KITLG,PAX6,RELN,SYBU,ARC" Pubmed 9225980 cDNAs with long CAG trinucleotide repeats from human brain. Pubmed 1.28E-06 2.23E-01 7.59E-04 9.60E-03 10 23 "EP400,CASK,MAGI1,NUMBL,NCOR2,MED12,TOX3,TNRC6A,ATXN2,JPH3" Pubmed 19036983 A crucial role for primary cilia in cortical morphogenesis. Pubmed 1.28E-06 2.23E-01 7.59E-04 9.60E-03 10 23 "AXIN2,LHX2,EMX2,EPHB1,TUBB3,MAPT,PAX6,RELN,PTCH1,IFT88" Pubmed 17015433 Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Pubmed 1.36E-06 2.37E-01 8.02E-04 1.02E-02 39 247 "TMCC3,MTUS1,THSD7A,PLAA,FAM189A2,AKAP7,RCHY1,CENPL,WDR20,DNAJB6,DNM1L,STARD3NL,POLK,ERGIC3,MTHFD2,COPS8,SPIN1,ICA1,NKD1,NPTX2,EXOSC10,PPP5C,SPDL1,RDX,DCUN1D2,SGSM1,CCDC112,TRA2B,EPC1,ZBTB43,RBM26,PDLIM2,MTMR14,WBP2,TRPS1,UBC,CCDC14,FAM47E,NELFE" Pubmed 24658140 The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Pubmed 1.42E-06 2.47E-01 8.36E-04 1.06E-02 26 133 "APBB2,ARRB1,ARRB2,ARHGEF7,CALM1,SOCS6,SH2B1,PDCD6IP,EGFR,ERBB2,ERBB4,BAIAP2,GABBR1,GRB10,MAPT,NTRK2,MAPK9,PTK2,RET,RGS4,SH3GL3,SHC4,SLA,SNCA,VAV1,TUBA1A" Pubmed 20439489 "miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells." Pubmed 1.45E-06 2.53E-01 8.50E-04 1.08E-02 25 125 "WDR35,ADAM23,NRP2,CACNB4,LRBA,STOML1,UBXN2A,CTH,SPOCK2,PCOLCE2,PRDM5,GSTT2,PADI2,MAT2A,NEFH,PAX6,SNX10,RFX2,MRAS,KDM3A,SPP1,SSTR1,TRIM2,SIRT1,UBTF" Pubmed 16964442 Identification of candidate maternal-effect genes through comparison of multiple microarray data sets. Pubmed 1.58E-06 2.74E-01 9.20E-04 1.16E-02 15 52 "AMPD3,APBB2,RUNX1T1,USP2,IQGAP2,KIT,SMAD1,KITLG,SERPINI1,FBXW7,HSPA4L,TRO,ZNF23,NDRG4,ST7" Pubmed 28700664 "Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program." Pubmed 1.61E-06 2.80E-01 9.37E-04 1.19E-02 29 159 "SYN3,STX16,CAST,CERS5,CHN1,CRYM,ARHGEF10,DBN1,KIAA0753,RPS6KL1,HEYL,NCALD,FOXO3,CINP,GHR,DBF4,HSF2,IRF8,RBPJ,IL6ST,NEFH,NRCAM,IGSF11,PCSK5,SH3TC2,ENOX1,AP4E1,ZNF346,IFT88" Pubmed 25640309 Systematic identification of molecular links between core and candidate genes in breast cancer. Pubmed 1.63E-06 2.84E-01 9.45E-04 1.20E-02 33 194 "MTA3,APC,MADD,ATP1A3,ADGRB1,CFL2,SULT4A1,PICK1,BAG4,CRY2,GREB1,ENO2,ERBB2,GMPR2,FECH,SEPT9,STMN1,PRKCB,KLK6,BCAS3,QDPR,FBXW7,BAALC,CASC3,ZNF821,SIRT2,FAIM2,CLASP2,SYN1,PDLIM2,UCHL1,MTCH1,TUBA1A" Pubmed 19953087 Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. Pubmed 1.64E-06 2.85E-01 9.48E-04 1.20E-02 34 203 "AMPD2,KCNAB2,MARK4,RASL11B,BMPR1B,BTK,KCNAB3,DAPK3,TOM1,EGFR,EIF5,NSRP1,FGF12,FGFR1,BAIAP2,FLT1,CAMKK2,FYN,SEPT9,MAP4K5,KCNB1,KIFC3,MAP2,NTRK2,PRRT2,RGS3,TCP11L1,MAPK12,SGK1,SAMSN1,SYT1,WBP2,TOM1L2,KCNAB1" Pubmed 20381070 Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Pubmed 1.75E-06 3.04E-01 9.92E-04 1.26E-02 13 40 "ARHGDIA,SCRN1,DPYSL2,ENO2,TUBA1B,NEFM,RNH1,SNCA,SPTAN1,TPM1,TPM2,TUBB2A,UCHL1" Pubmed 24198358 A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. Pubmed 1.75E-06 3.04E-01 9.92E-04 1.26E-02 13 40 "TUBB3,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,IGF1,NEFH,NTRK2,NTRK3,RET" Pubmed 12473661 The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. Pubmed 1.75E-06 3.05E-01 9.92E-04 1.26E-02 5 5 "ARHGEF7,GIT2,PCLO,GIT1,PTK2" Pubmed 12764042 Choreography of early thalamocortical development. Pubmed 1.75E-06 3.05E-01 9.92E-04 1.26E-02 5 5 "EMX2,L1CAM,PAX6,RELN,SNAP25" Pubmed 12451131 Normal development of embryonic thalamocortical connectivity in the absence of evoked synaptic activity. Pubmed 1.75E-06 3.05E-01 9.92E-04 1.26E-02 5 5 "CALB1,CALB2,L1CAM,RELN,SNAP25" Pubmed 15834957 "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." Pubmed 1.75E-06 3.05E-01 9.92E-04 1.26E-02 5 5 "CRMP1,DPYSL2,MAP2,MAPT,DPYSL5" Pubmed 25053427 Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Pubmed 1.77E-06 3.08E-01 1.00E-03 1.26E-02 16 59 "CDC42BPA,VAT1L,JAZF1,RUNX1T1,CHGB,SPOCK2,CELSR3,FGF14,GHR,INSM1,NNAT,PAX6,SNRK,ARX,SNAP25,SST" Pubmed 18391951 Many sequence variants affecting diversity of adult human height. Pubmed 1.83E-06 3.17E-01 1.02E-03 1.29E-02 27 143 "HACE1,LCORL,NOG,ZBTB24,DDX46,DTNB,DNAJC27,PRAM1,STRADA,SPIN1,BVES,PDE3A,SERPINI1,RASGEF1B,BCAS3,PEX2,RBBP8,ZFHX4,RPS20,SH3GL3,KIF13A,ADAMTS17,CDK20,PPIL6,ZBTB38,ADAMTSL3,ADAMTS10" Pubmed 18799476 Identification of Arx transcriptional targets in the developing basal forebrain. Pubmed 1.83E-06 3.18E-01 1.02E-03 1.29E-02 9 19 "VAT1L,CALB1,HAP1,EBF1,MEF2C,KITLG,MAGEL2,ARX,SST" Pubmed 15529118 Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation. Pubmed 1.83E-06 3.18E-01 1.02E-03 1.29E-02 9 19 "SYN3,APLP1,KIF5A,MAPT,SYN1,SYN2,SYP,SYT1,KLC2" Pubmed 23042737 Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Pubmed 1.93E-06 3.35E-01 1.07E-03 1.35E-02 11 29 "AXIN2,BMP7,CALB1,CALB2,SLIT2,TUBB3,L1CAM,NFIX,MAPK3,PTCH1,SATB2" Pubmed 16186258 Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. Pubmed 1.93E-06 3.35E-01 1.07E-03 1.35E-02 11 29 "CASKIN1,PPFIA3,CASK,CDH2,ERBB4,GRIA2,NLGN3,NLGN1,SNAP25,STXBP1,SYP" Pubmed 21998595 "Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry." Pubmed 1.93E-06 3.35E-01 1.07E-03 1.35E-02 11 29 "SYN3,ZFAT,LCORL,SMIM29,ARSE,DCLK1,ENPP2,CCDC88A,TNS1,ZBTB38,ADAMTSL3" Pubmed 21078624 Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Pubmed 2.00E-06 3.48E-01 1.10E-03 1.39E-02 24 119 "ACTN1,C1QTNF1,LTBP4,CACNA1A,KALRN,ARHGAP22,SUMF2,CRMP1,GPRASP1,IP6K1,NELFCD,KHDRBS3,SRRM4,MATK,MATN2,NELL2,PCSK5,ATXN7,SCP2,PUF60,HECW1,ITPRID2,MPRIP,RIMBP2" Pubmed 19924828 Expression of PTPRO in the interneurons of adult mouse olfactory bulb. Pubmed 2.01E-06 3.49E-01 1.10E-03 1.39E-02 7 11 "CALB1,CALB2,NCALD,GAD1,MAP2,PTPRO,UCHL1" Pubmed 12154121 Molecular mechanisms governing Pcdh-gamma gene expression: evidence for a multiple promoter and cis-alternative splicing model. Pubmed 2.01E-06 3.49E-01 1.10E-03 1.39E-02 7 11 "PCDHGB4,PCDHGC5,PCDHGB6,PCDHGB2,PCDHGA11,PCDHAC2,PCDHA5" Pubmed 9742148 Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. Pubmed 2.01E-06 3.49E-01 1.10E-03 1.39E-02 7 11 "CALB1,CALB2,CCK,GAD1,NPY,RELN,SST" Pubmed 23314748 Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? Pubmed 2.19E-06 3.81E-01 1.19E-03 1.51E-02 30 170 "KIAA1211,KLHL13,UNC79,CBR1,CDH2,SLIT2,RTTN,SOCS5,KIAA0586,TOM1,PHF20L1,MRPL37,TNRC6A,ZHX1,MAP4,PTOV1,HNRNPM,HYDIN,PTH1R,KLHL11,SGK1,NBPF1,SYNE2,DNAH7,CDH22,TIAM1,UBC,RPL7L1,TOM1L2,ZNF213" Pubmed 20713522 Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Pubmed 2.24E-06 3.89E-01 1.20E-03 1.52E-02 8 15 "CALB1,CALB2,ERBB4,GAD1,L1CAM,NPY,RELN,SST" Pubmed 10932191 "A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse." Pubmed 2.24E-06 3.89E-01 1.20E-03 1.52E-02 8 15 "HEPH,KIT,KITLG,AFF1,PMP22,FBXO11,SNAP25,ZIC2" Pubmed 23064108 Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs. Pubmed 2.24E-06 3.89E-01 1.20E-03 1.52E-02 8 15 "CALB1,CALB2,CCK,NPY,STX1B,SNAP25,STX1A,SLC17A7" Pubmed 10679268 "Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains." Pubmed 2.24E-06 3.89E-01 1.20E-03 1.52E-02 8 15 "SH2B1,CSF1R,PTK2B,JAK2,KIT,MATK,PIK3R1,VAV1" Pubmed 17462911 STAT5A/B activity is required in the developing forebrain and spinal cord. Pubmed 2.24E-06 3.89E-01 1.20E-03 1.52E-02 8 15 "CALB2,DLX1,ETV1,TUBB3,STMN2,L1CAM,RELN,RORB" Pubmed 20816195 Analyses of shared genetic factors between asthma and obesity in children. Pubmed 2.29E-06 3.98E-01 1.23E-03 1.55E-02 14 47 "ADRA1B,ADRB2,DPP10,STK33,IL33,SH2B1,DGKG,NEGR1,PDE4D,KCTD15,PTPRD,ROBO1,FAIM2,CHST8" Pubmed 27621311 Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate. Pubmed 2.64E-06 4.59E-01 1.41E-03 1.78E-02 98 878 "ACADM,ACTN1,CDC42BPA,DNAH17,ATP2A2,AZGP1,DST,SYNJ1,CALM1,CBR1,CBS,CFL2,PLAA,MYL6B,CLTC,MAGED1,RTTN,PUM1,EARS2,MATR3,AIF1L,DBN1,DBT,ZC3H11A,PDCD6IP,FARSB,EEF1D,EIF4G1,EIF4G2,EPB41L2,MTSS1L,SRRM1,ACSL4,TUBA1B,TUBB3,RACK1,SEC24B,FHL1,SYNCRIP,NOP56,DCTN2,SPECC1,OGA,RNPS1,CNTRL,GSN,PSIP1,DDX19B,ACOT7,IDH3A,IDH3B,MYLK2,IPO5,MAT2A,MBNL1,AFDN,MOV10,MPP2,HNRNPM,NEFM,NFE2L2,CHAMP1,TMOD2,PGAM2,PKM,PLEC,PPP3CC,PRPSAP2,PSMA6,QRICH1,ANKHD1,RIPOR1,RNH1,RPL15,RPS20,SAFB,SARS,COPZ1,MYO18A,SHMT2,CHD9,SLC6A11,SNRPN,SPTAN1,TROVE2,LARP4,MPRIP,SYNE2,USP22,METTL3,TUBB2A,XPO1,INTS3,SLC30A4,MDH1B,FAM182B,HNRNPA3,AAAS" Pubmed 23414517 A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. Pubmed 2.66E-06 4.63E-01 1.42E-03 1.79E-02 19 82 "CDC42BPA,MYOM1,DST,CAPN3,AKAP6,APPL1,DNAJB6,OPTN,FLNC,LIMS1,BLOC1S2,ZNF426,RDX,SPTB,SYNE2,ANKRD28,DOCK9,WIPF1,SH3GLB2" Pubmed 18839409 Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "HS3ST2,NEFH,NTRK2,NTRK3,RET,UCHL1" Pubmed 22982106 Distribution of protocadherin 9 protein in the developing mouse nervous system. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "PCDH10,CALB1,CALB2,NEFH,PCDH9,PRPH" Pubmed 9736654 TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "NTRK2,NTRK3,SNAP25,STX1A,SYP,SYT1" Pubmed 22298430 Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "ARHGEF2,USP21,MAP4,MARK1,MARK3,UBC" Pubmed 12963086 Co-purification and localization of Munc18-1 (p67) and Cdk5 with neuronal cytoskeletal proteins. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "MAPT,NEFM,NEFH,STX1A,STXBP1,TUBB2A" Pubmed 23931996 Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "CALB2,CDH2,NECTIN3,TUBB3,AFDN,RELN" Pubmed 658175 Studies of erythrocyte protoporphyrin in anemic mutant mice: use of a modified hematofluorometer for the detection of heterozygotes for hemolytic disease. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "HEPH,KIT,KITLG,SLC11A2,CDK5RAP2,SPTB" Pubmed 12895513 Development of the mouse neuromuscular junction in the absence of regulated secretion. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "SYN3,ACHE,NEFH,STXBP1,SYN1,SYN2" Pubmed 23482493 CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Pubmed 2.79E-06 4.85E-01 1.44E-03 1.83E-02 6 8 "CLIP3,TUBB3,PRPH,CLIP1,S100B,CLIP2" Pubmed 20181579 The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. Pubmed 2.85E-06 4.96E-01 1.47E-03 1.86E-02 11 30 "CALB1,CALB2,DLX1,ETV1,TUBB3,PPP1R1B,GAD1,GNAL,NPY,SST,ZIC1" Pubmed 22711842 Wnt/?-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Pubmed 2.85E-06 4.96E-01 1.47E-03 1.86E-02 11 30 "AXIN2,BMP7,NOG,HEYL,RBPJ,SMAD1,SMAD9,MEF2C,SMARCD3,MESP1,HEY1" Pubmed 15328020 A screen for downstream effectors of Neurogenin2 in the embryonic neocortex. Pubmed 3.03E-06 5.26E-01 1.55E-03 1.96E-02 14 48 "CALB2,PTBP2,QKI,NCOR1,TUBB3,FUT9,STMN2,NEGR1,L1CAM,MAP2,MEF2C,PCDH9,NLGN1,SST" Pubmed 23382219 Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Pubmed 3.12E-06 5.42E-01 1.59E-03 2.01E-02 21 98 "ADRB2,ALK,DDR1,TAOK2,SLITRK5,EGFR,ERBB2,ERBB4,TLR7,ADGRV1,FGFR1,FLT1,GPR37,GPR62,LRP1B,NTRK2,NTRK3,PTPRB,PTPRN2,RET,VLDLR" Pubmed 17460091 "Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation." Pubmed 3.12E-06 5.42E-01 1.59E-03 2.01E-02 9 20 "CALB1,CALB2,EBF1,ETV1,PPP1R1B,GAD1,MAP2,NPY,ARX" Pubmed 25467980 NPAS1 represses the generation of specific subtypes of cortical interneurons. Pubmed 3.22E-06 5.60E-01 1.63E-03 2.06E-02 10 25 "CALB2,DLX1,ERBB4,FGFR1,FGFR3,GAD1,NPY,RELN,ARX,SST" Pubmed 23359859 NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Pubmed 3.22E-06 5.60E-01 1.63E-03 2.06E-02 10 25 "SYNGR3,RASGRP2,STX2,GABBR1,NOVA1,NOVA2,RASGRF1,DZIP1,SLC4A3,CDK5RAP2" Pubmed 15935055 "Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation." Pubmed 3.22E-06 5.60E-01 1.63E-03 2.06E-02 10 25 "DOC2A,CALB1,SCAMP5,STX1B,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYP" Pubmed 21795542 Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. Pubmed 3.25E-06 5.66E-01 1.64E-03 2.07E-02 13 42 "LGR5,BMPR1B,PLPPR4,PCDH17,FAM19A2,IFI16,IGF1,NPR2,PCDH8,PCDH9,CYTL1,ZFPM2,FZD3" Pubmed 29459677 A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Pubmed 3.49E-06 6.07E-01 1.76E-03 2.22E-02 38 247 "BEND6,ZBTB10,C5,HIP1R,DLGAP2,CLTC,MAP4K4,ARMC8,OSBPL3,PHF14,SGSM2,EGFR,TUBD1,TUBA1B,TUBB3,SMC2,ARFIP1,LRRCC1,SYTL4,AFDN,GIT1,HNRNPM,PLEC,PTPN13,PCMTD2,RYR3,CCDC112,ATXN7,BTBD3,ZFP1,SNRPN,SPTAN1,IQCE,METTL3,TRIO,TUBB2A,UBC,TUBA1A" Pubmed 14676191 Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. Pubmed 3.61E-06 6.28E-01 1.81E-03 2.29E-02 17 69 "MARK4,CCAR2,ARHGEF2,BRINP1,PARD6A,STRADA,RASSF8,LIMS1,MARK1,MARK3,PNMA3,PNMA8A,MYO18A,CCDC88A,SMARCA4,MTCL1,PARD3" Pubmed 28190767 An Interaction Landscape of Ubiquitin Signaling. Pubmed 3.70E-06 6.43E-01 1.85E-03 2.34E-02 60 468 "ACTN1,BRAP,AP2A1,AP2A2,OSBPL8,OGT,USP37,KIF1A,BARD1,HAP1,ARHGEF2,EPS15L1,PLAA,HECTD1,UBXN2A,TCAF1,TBC1D5,DBT,SPATA2,DDX46,USP3,PDCD6IP,TOM1,OPTN,COPS4,TNK2,GPHN,ERCC2,ATP5PD,NEURL4,USP19,DDX19B,ELOVL5,GABARAPL2,MYO5A,MYO6,PDPK1,OLA1,PLEC,MBOAT7,PPM1B,LAMA1,USP47,PCMTD2,RMI1,CCDC92,EPN2,SPTAN1,NSFL1C,KLHL7,ALG1,AGTPBP1,UBC,UBE3A,UCHL1,TOM1L2,CCDC14,TBC1D15,ZFAND5,UBE3B" Pubmed 19019082 Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. Pubmed 3.97E-06 6.89E-01 1.98E-03 2.50E-02 14 49 "CASK,MARK4,ATP1A1,ATP2A2,CBS,CRMP1,SCRN1,TMCC2,DCTN2,MAT2A,MEST,ZNF302,STXBP1,TUBB2A" Pubmed 18199763 Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. Pubmed 4.14E-06 7.20E-01 2.05E-03 2.59E-02 11 31 "CALB2,NGEF,NECTIN3,EBF1,PPP1R1B,MAP2,MEIS2,RELN,FIGN,SST,NETO1" Pubmed 22357600 The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Pubmed 4.14E-06 7.20E-01 2.05E-03 2.59E-02 11 31 "CASK,CADPS,FUBP1,CACNA1B,CALB1,GABRG2,NRCAM,PBRM1,SCN8A,SNAP25,CAMTA1" Pubmed 2288909 Multiple genes encoding zinc finger domains are expressed in human T cells. Pubmed 4.14E-06 7.20E-01 2.05E-03 2.59E-02 11 31 "ZNF44,ZFP1,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZNF45,ZNF30" Pubmed 24142862 Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons. Pubmed 4.20E-06 7.30E-01 2.05E-03 2.59E-02 8 16 "CALB1,CALB2,EGFR,ERBB2,ERBB4,TUBB3,GAD1,SST" Pubmed 19138174 "Channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics." Pubmed 4.20E-06 7.30E-01 2.05E-03 2.59E-02 8 16 "CAMK2A,CAMK2B,GDA,BAIAP2,PPP3CA,PRKCB,TUBB2A,TUBA1A" Pubmed 15572149 The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Pubmed 4.20E-06 7.30E-01 2.05E-03 2.59E-02 8 16 "CALB2,L1CAM,MAP2,MAPK9,MAPK10,PTK2,SNAP25,STXBP1" Pubmed 22575789 Localization of septin proteins in the mouse cochlea. Pubmed 4.20E-06 7.30E-01 2.05E-03 2.59E-02 8 16 "SEPT7,TUBB3,SEPT9,MYO7A,SEPT4,SEPT8,SEPT3,SYP" Pubmed 14594945 MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes. Pubmed 4.20E-06 7.30E-01 2.05E-03 2.59E-02 8 16 "MARK4,MAP2,MAP4,MAPT,MARK1,MARK3,TUBB2A,TUBA1A" Pubmed 22696295 Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Pubmed 4.37E-06 7.59E-01 2.12E-03 2.68E-02 13 43 "ALCAM,BMP7,SLIT2,CHL1,ATOH8,LAMA2,KITLG,NRCAM,PLCL1,PTCH1,ARX,TCF12,HEY1" Pubmed 22566634 The genetic architecture of economic and political preferences. Pubmed 4.48E-06 7.79E-01 2.17E-03 2.75E-02 12 37 "CADPS,DLGAP1,AKAP6,RGS6,PLXNA4,RAB30,CNTN3,PDE4B,ASTN2,DCBLD1,EML6,NETO1" Pubmed 20830809 Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Pubmed 4.53E-06 7.87E-01 2.17E-03 2.75E-02 7 12 "TUBB3,GLUL,COL28A1,NEFH,PRPH,RDX,S100B" Pubmed 20151419 Differential gene expression in migrating cortical interneurons during mouse forebrain development. Pubmed 4.53E-06 7.87E-01 2.17E-03 2.75E-02 7 12 "CALB1,DGKG,CHL1,GAD1,PTPRT,MGAT5B,WNT7A" Pubmed 18796539 alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. Pubmed 4.53E-06 7.87E-01 2.17E-03 2.75E-02 7 12 "SPTBN4,EPB41,EPB41L2,TUBB3,MYO7A,SPTAN1,SPTB" Pubmed 11572484 Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. Pubmed 4.53E-06 7.88E-01 2.17E-03 2.75E-02 16 63 "XKR4,FMNL2,KLHL32,TMEM132B,ELFN2,PSMG3-AS1,CCDC85A,GALNT13,RNF157,PWWP2A,SCIN,NEK1,RIPOR1,LGI2,ITPRID2,CSMD1" Pubmed 25910212 Widespread macromolecular interaction perturbations in human genetic disorders. Pubmed 4.68E-06 8.14E-01 2.24E-03 2.83E-02 59 461 "ACTN1,GPRASP2,AMPD3,ASPA,BTK,CA8,CACNB4,LURAP1,KRIT1,ZBED1,CFL2,CHN1,FBXO7,HOMER3,FHL5,MAGED1,CRYBB1,CSNK1E,PDE4DIP,KATNAL2,JAKMIP2,DMD,EBF1,OPTN,GOLGA7,IRAK4,HSD17B14,MRPL10,RACK1,FDFT1,AMOTL2,KHDRBS3,GGT7,GLUL,LNX1,ZNF496,HSF2,LIG4,KCTD6,MID1,NCF2,PMP22,C19orf57,GRAMD1C,SPDL1,RAD51D,KHDRBS2,CDK5RAP3,SPP1,STXBP1,MTMR14,EIF4ENIF1,BCL2L13,XRCC4,ZNF24,MKRN3,SH3GLB2,TFIP11,PRTFDC1" Pubmed 12467588 Gamma protocadherins are required for survival of spinal interneurons. Pubmed 4.91E-06 8.54E-01 2.34E-03 2.96E-02 10 26 "ALCAM,CALB1,GPHN,GAD1,MAP2,PCDHGC3,RELN,SYN1,SYP,PCDHB15" Pubmed 15778465 "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer." Pubmed 5.01E-06 8.71E-01 2.38E-03 3.01E-02 20 93 "APC,SYNJ2,MAGI1,OSBPL3,SIPA1L1,ARHGAP32,HDAC4,ZNF638,PARD3B,MARK1,MARK3,PTOV1,MAPKAP1,MYCBP2,ST5,MPRIP,PARD3,KLC2,SPIRE1,GAN" Pubmed 19923290 The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis. Pubmed 5.12E-06 8.90E-01 2.42E-03 3.06E-02 9 21 "NUMB,CDH2,ETV1,TUBB3,FGFR1,PAX6,MAPK3,CUX2,PARD3" Pubmed 17582329 Dlx transcription factors promote migration through repression of axon and dendrite growth. Pubmed 5.12E-06 8.90E-01 2.42E-03 3.06E-02 9 21 "NRP2,ELMO1,DLX1,ERBB4,GAD1,MAP2,MAPT,MEF2C,ROBO1" Pubmed 17192257 Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Pubmed 5.15E-06 8.95E-01 2.42E-03 3.06E-02 18 78 "CDK10,MARK4,CAMK2G,MAP4K4,CSNK1E,EGFR,PTK2B,FER,FYN,MAP4K5,MARK1,MARK3,CDK18,PRKCB,MAPK3,MAPK9,PTK2,RPS6KA2" Pubmed 23793025 Genome-wide meta-analysis identifies new susceptibility loci for migraine. Pubmed 5.15E-06 8.95E-01 2.42E-03 3.06E-02 18 78 "ADRA1B,TRMT9B,FHL5,MRPL37,EYA1,MRVI1,NBEA,GFRA2,MMP16,KSR2,CNNM2,PTPRD,SUGCT,LIMCH1,KANK1,ASTN2,NSD1,TSC1" Pubmed 29091030 CHIP as a membrane-shuttling proteostasis sensor. Pubmed 5.66E-06 9.84E-01 2.65E-03 3.35E-02 16 64 "BIN1,ARHGAP33,DNAJB6,BAIAP2,VTI1B,WDR83,SRCAP,PRRC2B,KIFC3,GPSM2,STAU1,DNAJC9,TAF6,FBXW11,TCF4,AAAS" Pubmed 24163370 "The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition." Pubmed 5.69E-06 9.90E-01 2.66E-03 3.36E-02 41 281 "NCKAP5,HECW2,RTL9,OSBPL8,EP400,SCAPER,KIAA0586,MED12,PHC2,EEF1D,ACSL4,SCML2,PRMT5,KAT8,BAIAP2,SPECC1,USP21,FAM120B,SRCAP,ZNF638,GRB10,DIDO1,CIT,MAP2,MARK1,KCTD6,CHAMP1,XRN1,RBBP6,ZMAT4,MORC4,PBRM1,ZC3H14,SUPT20H,KDM4D,RADIL,SP2,HECW1,CABIN1,TSC2,SPHK2" Pubmed 11812828 Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Pubmed 5.70E-06 9.91E-01 2.66E-03 3.36E-02 24 126 "MADD,FAM19A5,PARD6A,DNAJB6,PAN3,MRPL10,STAU2,FERMT2,TOX2,AFDN,CCDC13,PKM,ANKHD1,PTX3,RDX,DUSP15,ZFHX4,SPTAN1,AGTPBP1,FRYL,FAM124A,FLRT2,VIPR2,MEIS3" Pubmed 19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Pubmed 5.93E-06 1.00E+00 2.76E-03 3.48E-02 23 118 "ACHE,ADCY8,ADORA2A,BCHE,RGS9,CAMK2A,CAMK2B,CHRNA4,GRIN3A,PPP1R1B,GAD1,GLUL,GRIA2,GRIN2C,GRIN2D,GRM2,GRM8,HNMT,NTRK2,ZDHHC8,RELN,SNAP25,SLC17A7" Pubmed 25807483 Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Pubmed 5.95E-06 1.00E+00 2.76E-03 3.49E-02 20 94 "CC2D2A,SEMA6A,SLIT2,HECTD1,CCDC151,EVL,CNTRL,ADAMTS6,PCSK5,PKD1,MAPK7,QRICH1,RFX3,KIF7,ROBO1,FUZ,SMARCA4,WRN,ZBTB14,IFT88" Pubmed 14759258 An unappreciated role for RNA surveillance. Pubmed 6.08E-06 1.00E+00 2.80E-03 3.55E-02 21 102 "CHRD,ATP1A1,CFLAR,CD38,PPT2,DMPK,DTNB,CELF1,GABBR1,MAN2A2,MAP2,MAP4,ADAM11,ADAM22,MSR1,NPR2,SETD4,PDE4A,PTPRD,RAD51D,SH3BP2" Pubmed 11214970 Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 6.08E-06 1.00E+00 2.80E-03 3.55E-02 21 102 "TMEM108,DLC1,KNDC1,LRRCC1,KIAA1755,DISP2,SETD5,KIF21A,AMBRA1,FHOD3,NBPF1,TET1,CPEB4,BDP1,TEX2,KLHL4,SYNE1,ASXL3,BHLHB9,WNK2,SENP7" Pubmed 18579678 Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Pubmed 6.14E-06 1.00E+00 2.82E-03 3.57E-02 12 38 "NOG,LHX2,ETV1,TUBB3,GRIK4,RBPJ,KITLG,RELN,ROBO1,RORB,CUX2,HEY1" Pubmed 20301317 Hereditary Ataxia Overview Pubmed 6.24E-06 1.00E+00 2.85E-03 3.61E-02 18 79 "ATP1A3,CACNA1A,CACNB4,SACS,FGF12,FGF14,NOP56,ELOVL5,TMEM240,PPP2R2B,APTX,LAMA1,ATXN2,ATXN7,ELOVL4,TTBK2,PDSS1,PDSS2" Pubmed 29121065 Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase. Pubmed 6.24E-06 1.00E+00 2.85E-03 3.61E-02 18 79 "CLK4,AP2A1,PPFIA3,CDK13,NUMB,NUMBL,DZIP3,ERC2,LNX1,CIT,MID1,KIF7,KLHL11,FBXO11,MYCBP2,ERC1,DNAJC9,ZNF24" Pubmed 15057823 The DNA sequence and analysis of human chromosome 13. Pubmed 6.40E-06 1.00E+00 2.92E-03 3.69E-02 29 170 "RCBTB2,SLITRK5,SACS,FRY,MBNL2,PAN3,KATNAL1,FGF14,UFM1,PCDH17,GPR12,SERP2,LIG4,HS6ST3,CHAMP1,PCDH9,DCUN1D2,SUPT20H,FNDC3A,MYCBP2,ZC3H13,RBM26,SPART,THSD1,DOCK9,ZIC2,UPF3A,ZDHHC20,SPATA13" Pubmed 23453885 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Pubmed 7.02E-06 1.00E+00 3.20E-03 4.04E-02 16 65 "AS3MT,MAP4K4,HDAC4,ZNF804A,MPP6,MMP16,NTRK3,PPP2R2B,CNNM2,GLT8D1,TCF4,SYNE1,ZFPM2,CSMD1,FAM155A,ANKS1B" Pubmed 25402006 In silico prediction of physical protein interactions and characterization of interactome orphans. Pubmed 7.10E-06 1.00E+00 3.22E-03 4.07E-02 25 136 "APBB2,ARRB1,ARRB2,RIPK1,ARHGEF7,CALM1,SOCS6,SH2B1,PDCD6IP,EGFR,BAIAP2,GRB10,MAPT,NTRK2,MAPK9,PTK2,RET,RGS4,SH3GL3,SHC4,SLA,SNCA,TCF4,VAV1,TUBA1A" Pubmed 15147765 Emx1 and Emx2 cooperate in initial phase of archipallium development. Pubmed 7.31E-06 1.00E+00 3.31E-03 4.19E-02 10 27 "NRP2,NOG,LHX2,CNTN1,DLX1,EMX2,EPHB1,KITLG,CNTN3,PAX6" Pubmed 17721516 OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Pubmed 7.45E-06 1.00E+00 3.35E-03 4.23E-02 8 17 "PCDH10,NRP2,CALB2,EBF1,EMX2,PPP1R1B,L1CAM,PAX6" Pubmed 23022035 p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration. Pubmed 7.45E-06 1.00E+00 3.35E-03 4.23E-02 8 17 "CALB1,PARD6A,TUBB3,GAD1,GSN,NPY,SST,CUX2" Pubmed 17376983 Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation. Pubmed 7.45E-06 1.00E+00 3.35E-03 4.23E-02 8 17 "DLX1,ERBB4,ETV1,GAD1,PAX6,RELN,ROBO1,ROBO2" Pubmed 23455922 Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Pubmed 7.51E-06 1.00E+00 3.36E-03 4.25E-02 57 447 "AXIN2,TAOK1,ZNF687,DYNLL1,ATP1A1,ATP2A2,BACH1,DST,ARHGEF7,CCNT1,HECTD1,ARHGEF6,AKAP7,AKAP5,MAGED1,CSNK1E,PDE4DIP,RASSF2,SEC16A,YAF2,VPS13B,SRRM1,PRMT5,PRKAG2,SEC23B,C2orf88,RNPS1,LIMS1,AFF1,MOV10,GIT1,ADAM22,CDK18,PKM,STRN3,PRKAB2,PRKACB,PRKAR1B,PRKCB,SNX22,RPS6KA2,ZNF568,DHX30,LIMS2,CDK5RAP2,ZSWIM8,ERC1,CLASP2,STAU1,PRRC2C,MMS19,FBXW11,OBSL1,TNS2,DICER1,GPR161,STOX2" Pubmed 22723691 Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord. Pubmed 7.53E-06 1.00E+00 3.36E-03 4.25E-02 18 80 "GRIN3A,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,OPRL1,SSTR1,SSTR2,TACR1,VIPR2" Pubmed 25332235 Substrate trapping proteomics reveals targets of the ?TrCP2/FBXW11 ubiquitin ligase. Pubmed 7.55E-06 1.00E+00 3.37E-03 4.26E-02 24 128 "AXIN2,OGT,EPB41L5,USP37,CDC25B,MAGI1,CBARP,CLTC,MTSS1L,FLNC,TUBGCP4,NFE2L2,PLEC,PTPN13,EML5,USP47,KCTD17,FNIP1,ELMO2,TACC1,FBXW11,TIAM1,UBC,TRIM9" Pubmed 22365545 A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Pubmed 7.64E-06 1.00E+00 3.40E-03 4.30E-02 13 45 "AXIN2,BMP7,CALB2,SLIT2,EPHB1,L1CAM,SMAD1,SMAD9,NBL1,PAX6,SATB2,CUX2,ZIC1" Pubmed 12923177 Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. Pubmed 7.87E-06 1.00E+00 3.49E-03 4.41E-02 6 9 "PPFIA4,PPFIA3,CAST,ERC2,GIT1,ERC1" Pubmed 16778019 Characterization of the piRNA complex from rat testes. Pubmed 7.94E-06 1.00E+00 3.51E-03 4.44E-02 23 120 "USP31,ARHGAP20,CDK10,ZBTB10,USP2,SEC31B,IP6K1,SLC43A2,DNAJC27,FKTN,ANKFY1,SPIN1,DDX19B,SMIM7,PRKAB2,RAD51D,KDM3A,ZC3H4,TACC1,RPGRIP1L,CBX5,NR2C2,STXBP4" Pubmed 26950368 Diverse functions of myosin VI elucidated by an isoform-specific ?-helix domain. Pubmed 8.12E-06 1.00E+00 3.56E-03 4.50E-02 9 22 "AP2A1,AP2A2,COPB2,CLTC,DCTN1,SEC16A,DCTN2,MYO6,PIK3C2A" Pubmed 18371380 Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Pubmed 8.12E-06 1.00E+00 3.56E-03 4.50E-02 9 22 "APC,TUBB3,MAP2,MBP,NEFH,NF1,MAPK3,SYN1,SYP" Pubmed 20534675 Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Pubmed 8.12E-06 1.00E+00 3.56E-03 4.50E-02 9 22 "EBF1,GFRA2,NEFH,NTRK2,NTRK3,PRPH,RET,UCHL1,SLC17A7" Pubmed 24595293 "Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration." Pubmed 8.12E-06 1.00E+00 3.56E-03 4.50E-02 9 22 "ETV1,TUBB3,MAP2,NEFH,PAX6,RELN,RORB,SATB2,CUX2" Pubmed 15761153 High-throughput mapping of a dynamic signaling network in mammalian cells. Pubmed 8.21E-06 1.00E+00 3.59E-03 4.54E-02 38 256 "APBB2,BMPR1B,ARHGEF7,ARHGEF1,SOCS6,CHN1,CHN2,PLEKHB1,FHL5,ARHGEF6,RNF14,OSBPL3,PPP1R16B,GIT2,RHOBTB1,PARD6A,RASL12,UBE2E3,MEX3B,USP21,RAB30,CLASRP,SMAP1,IRF8,INPP5B,LIMS1,LMO2,SMAD1,GNG2,SH3KBP1,PPP2R2B,PPP3CC,RGS3,PREX2,TTC17,RASD2,UBTF,RNF146" Pubmed 19460752 A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. Pubmed 8.23E-06 1.00E+00 3.59E-03 4.54E-02 34 218 "NDRG3,ADD2,ARNTL,MYOM1,RGS11,NRP2,CAPN3,NPIPA1,FAM149A,KIAA0408,DTNA,TSPAN5,EPB41,TUBA1B,FOXO3,AFF2,TPK1,GALC,RAPGEF6,PRDM5,SMAP1,IL6ST,CDK18,PKD1,SNX10,RGS4,RIC8B,SH3BGR,CXXC4,FAM208A,WSCD1,TCF12,DICER1,TUBA1A" Pubmed 26671461 Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Pubmed 8.31E-06 1.00E+00 3.60E-03 4.55E-02 12 39 "AXIN2,CALB2,LHX2,DLX1,EMX2,ETV1,SMAD1,PAX6,RELN,RORB,PDZRN3,CUX2" Pubmed 20943929 "The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence." Pubmed 8.32E-06 1.00E+00 3.60E-03 4.55E-02 11 33 "SEMA6A,NRP2,LHX2,EBF1,EMX2,TUBB3,PAX6,RELN,PTCH1,RORB,SATB2" Pubmed 28069946 Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Pubmed 8.32E-06 1.00E+00 3.60E-03 4.55E-02 11 33 "AXIN2,CAMK2A,CAMK2B,GRIA2,MAP2,NEFH,MAPK3,SYN1,SYP,WNT7A,SLC17A7" Pubmed 18022353 New nomenclature for chromatin-modifying enzymes. Pubmed 8.52E-06 1.00E+00 3.67E-03 4.65E-02 14 52 "KDM5D,NCOA1,CLOCK,KMT5B,KAT8,DOT1L,KDM2B,KAT7,KDM4D,KDM4B,KDM3A,KDM4C,NSD1,KAT6A" Pubmed 21399614 Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Pubmed 8.54E-06 1.00E+00 3.67E-03 4.65E-02 26 146 "DYNLL1,PDE4DIP,KIAA0586,DCTN1,KIAA0753,DCTN4,CEP85L,CEP78,DCTN2,TUBGCP4,CNTRL,LRRCC1,KIF2A,POC1B,NEK1,PRKACB,CEP41,PPP2R3C,CEP97,CLIP1,CDK5RAP2,CEP68,FBXW11,RPGRIP1L,CLASP1,CCDC14" Pubmed 16987237 Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. Pubmed 8.67E-06 1.00E+00 3.72E-03 4.71E-02 16 66 "ACHE,CACNA1A,CCK,DLGAP1,PICK1,ENO2,GPHN,GAD1,PCLO,NPY,CNTN3,PCSK1,SST,SSTR1,STXBP1,TACR1" Pubmed 25036637 A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. Pubmed 8.98E-06 1.00E+00 3.74E-03 4.73E-02 45 326 "ACTN1,GPRASP2,BIN1,AMT,DNAH17,ATP2A2,COPB2,HECTD1,MAGED1,BAG4,SEC24C,VCAN,DNAJB6,EGFR,ERBB2,ERBB4,TUBA1B,FER,USP19,HSF2,HSPA1L,KLHL23,POC1B,HNRNPM,DNHD1,KSR2,PDCD2,PIK3R1,SH3KBP1,PPP5C,PRPSAP2,CEP97,RADX,MCMBP,FAM192A,COPZ1,HSPA4L,PHLDB1,SYNE2,DNAJC9,WBP2,HSPBP1,XPO1,DHX33,TUBA1A" Pubmed 26354767 Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Pubmed 9.17E-06 1.00E+00 3.74E-03 4.73E-02 23 121 "AP2A1,DDO,LINC00173,NECTIN3,NCOR1,CYBB,ALKBH8,PHF20L1,KATNAL1,TUBA1B,DLC1,CINP,DIDO1,LRRTM1,CDK18,SPDL1,PTPRN2,FBXW7,TNFRSF19,PUF60,NELFE,RSPRY1,SENP7" Pubmed 9012511 Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "EDN1,EDN3,EDNRA,EDNRB,KITLG" Pubmed 17244534 Ubiquitin binds to and regulates a subset of SH3 domains. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "AMPH,BIN1,DNM1,SH3KBP1,UBC" Pubmed 27609886 Identification of an elaborate complex mediating postsynaptic inhibition. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "ARHGAP32,GPHN,INSYN1,IQSEC3,ARHGEF9" Pubmed 23516305 Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "TUBB3,NTRK2,NTRK3,PTPRO,RET" Pubmed 18054781 "The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons." Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "CALB1,SLIT2,ROBO1,ROBO2,ARX" Pubmed 19029029 Control of patterns of corneal innervation by Pax6. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "TUBB3,NTRK2,NTRK3,PAX6,TACR1" Pubmed 10449403 A conformational switch in syntaxin during exocytosis: role of munc18. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "CPLX2,CPLX1,SNAP25,STX1A,STXBP1" Pubmed 20037577 HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "DNM1,KIF2A,KIF5A,XPO1,TUBA1A" Pubmed 26987813 Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at G?i/o. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "RGS6,GPSM1,GPSM2,RGS4,RGS12" Pubmed 16374801 Neural activity- and development-dependent expression and distribution of CASK interacting nucleosome assembly protein in mouse brain. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "CASK,TUBB3,TSPYL2,SYP,TAF9" Pubmed 23666762 Role of individual MARK isoforms in phosphorylation of tau at Ser²?² in Alzheimer's disease. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "MARK4,MAPT,MARK1,MARK3,PEG10" Pubmed 10648716 The lack of Emx2 causes impairment of Reelin signaling and defects of neuronal migration in the developing cerebral cortex. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "CALB2,EMX2,TUBB3,MAP2,RELN" Pubmed 19366869 The role of Robo3 in the development of cortical interneurons. Pubmed 9.18E-06 1.00E+00 3.74E-03 4.73E-02 5 6 "CALB1,GAD1,RELN,ROBO1,ROBO2" Pubmed 12561075 "Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding." Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "CALB2,LHX2,EMX2,TUBB3,L1CAM,RELN,RORB" Pubmed 20847152 Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "PCDH19,ETV1,L1CAM,PCDH8,PCDH9,RELN,CUX2" Pubmed 16873583 "Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes." Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "CALB1,CALB2,ETV1,TUBB3,RELN,RORB,CUX2" Pubmed 23142661 Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "CALB2,ETV1,GAD1,NPY,SATB1,SST,CUX2" Pubmed 26813976 Gradient COUP-TFI Expression Is Required for Functional Organization of the Hippocampal Septo-Temporal Longitudinal Axis. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "NRP2,CALB1,CALB2,GAD1,GRIK4,MAP2,NEFH" Pubmed 29045729 Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "CALB1,CALB2,KIAA0319,NEFH,PAX6,RELN,SST" Pubmed 18279309 Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "CALB1,GLUL,SYP,PCDHB15,PCDHB6,PCDHB4,PCDHB3" Pubmed 27223325 NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Pubmed 9.22E-06 1.00E+00 3.74E-03 4.73E-02 7 13 "SLIT2,L1CAM,NEFH,NOVA1,NOVA2,ROBO2,SYP" Pubmed 19208628 The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. Pubmed 1.07E-05 1.00E+00 4.32E-03 5.46E-02 10 28 "ARHGEF7,CAMK2A,DLGAP1,SHANK1,BAIAP2,SYNPO,MAP2,DBNL,SPTAN1,ARC" Pubmed 22923088 The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Pubmed 1.10E-05 1.00E+00 4.45E-03 5.63E-02 15 60 "AXIN2,NRP2,BMP7,CALB2,LHX2,EMX2,EPHB1,ETV1,GRIK4,L1CAM,PAX6,RELN,RORB,SATB2,CUX2" Pubmed 15561718 Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. Pubmed 1.11E-05 1.00E+00 4.48E-03 5.67E-02 12 40 "SEMA6A,CASP8AP2,ETV1,TCERG1,STMN2,MEF2C,HNRNPM,SATB1,KAT6B,HIRA,ZNF24,NELFE" Pubmed 22407321 MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Pubmed 1.15E-05 1.00E+00 4.64E-03 5.86E-02 11 34 "SEMA7A,CALB1,VCAN,SEMA3D,MEGF11,MEGF10,GALNT15,GLUL,HAS2,MMP17,NPY" Pubmed 19521500 The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Pubmed 1.17E-05 1.00E+00 4.69E-03 5.92E-02 35 231 "ADD2,OGT,ADGRB3,DDX46,KLHL5,ING4,ETV1,TUBB3,FGFR1,SESN1,CBX1,IDH3A,MEST,KCTD6,NELL2,NFYA,NTRK2,IGSF11,PAX6,ENPP2,GPR85,FAM98B,PKM,PEX2,RDX,ELP2,RPS20,PUF60,KBTBD4,ZC3H4,TAF9,TBL1X,MTMR14,UBTF,PLPPR2" Pubmed 20571754 Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Pubmed 1.21E-05 1.00E+00 4.83E-03 6.10E-02 17 75 "ADCY5,APOC1,APOC2,LGR5,MADD,STK33,SH2B1,CRY2,DGKB,HMGCR,NEGR1,IGF1,PCSK1,KCTD15,PLTP,SARS,AGMO" Pubmed 28705898 Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Pubmed 1.21E-05 1.00E+00 4.85E-03 6.14E-02 23 123 "AXIN2,SEMA6A,CALB1,CRLF1,COL9A3,PPP1R1B,KHDRBS3,NSG1,KDM2B,ACOT7,NKD1,STMN1,MEST,MYCN,NNAT,NKAIN1,RET,C18orf54,TMPO,DOK6,RPRM,VLDLR,PCBP4" Pubmed 18250082 Gene expression in cortical interneuron precursors is prescient of their mature function. Pubmed 1.26E-05 1.00E+00 5.00E-03 6.32E-02 8 18 "CACNB4,GAD1,NPY,SATB1,SLC12A2,SST,CUX2,SSBP2" Pubmed 10393115 Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Pubmed 1.26E-05 1.00E+00 5.00E-03 6.32E-02 8 18 "CALB1,CALB2,ETV1,TUBB3,GAD1,GNAL,MAP2,PAX6" Pubmed 8653788 Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Pubmed 1.26E-05 1.00E+00 5.00E-03 6.32E-02 8 18 "ACHE,SV2B,DNM1,SYT3,SYT17,NEFH,SYP,SYT1" Pubmed 25515538 A systems-wide screen identifies substrates of the SCF?TrCP ubiquitin ligase. Pubmed 1.28E-05 1.00E+00 5.08E-03 6.43E-02 35 232 "LRCH2,APC,USP37,CDC25B,CLTC,HECTD1,BAG4,CRY2,SIPA1L1,PUM1,DCAF8,MATR3,FLNC,KHDRBS3,MOV10,MXI1,NACA,NFE2L2,PIK3C2A,PTPN13,EML5,USP47,FBXW7,SBF1,FNIP1,SHMT2,AMBRA1,SYBU,TACC1,FBXW11,EIF4ENIF1,ZIC2,TRIM9,SPIRE1,HNRNPA3" Pubmed 15449545 Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.30E-05 1.00E+00 5.11E-03 6.46E-02 18 83 "INTS2,CARMIL3,ARHGEF1,ZNF521,BOC,GGT7,CNTRL,TMEM104,ANKHD1,USP47,ARMC5,PEAR1,GALNT10,FAM102A,ARHGEF40,IFT122,DOCK8,LAS1L" Pubmed 25131634 Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice. Pubmed 1.30E-05 1.00E+00 5.11E-03 6.46E-02 18 83 "ACHE,BCHE,CAMK2A,CHRNA4,CSF1,VCAN,FCGR1A,GABRB3,GABRG1,MAPT,MBP,MSR1,NTRK2,NTRK3,PPP3CC,KCNIP3,MAPK12,SST" Pubmed 28942923 Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Pubmed 1.53E-05 1.00E+00 5.96E-03 7.54E-02 10 29 "CALB2,CCK,NDST3,CHST15,TOX3,HS6ST3,NFIX,SOX15,SST,HEY1" Pubmed 18077674 The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. Pubmed 1.53E-05 1.00E+00 5.96E-03 7.54E-02 10 29 "LARGE1,CNR1,GDA,KCNQ3,NPY,NPTX2,PPP3CA,FBXW7,SATB2,SLC17A7" Pubmed 22514301 c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. Pubmed 1.53E-05 1.00E+00 5.96E-03 7.54E-02 10 29 "CCK,EBF1,GFRA2,MAPT,NEFH,NTRK2,NTRK3,RET,RORB,SLC17A7" Pubmed 21909369 Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice. Pubmed 1.53E-05 1.00E+00 5.96E-03 7.54E-02 10 29 "SLC4A4,BMPR1B,AP4M1,KATNAL1,FGF11,PRUNE2,MAT2A,DZIP1,SPP1,TAF6" Pubmed 22906231 Neurog1 and Neurog2 coordinately regulate development of the olfactory system. Pubmed 1.58E-05 1.00E+00 6.13E-03 7.75E-02 11 35 "CALB2,DLX1,ETV1,GAD1,STMN2,NTRK2,NTRK3,PAX6,RELN,S100B,SLC17A7" Pubmed 29078390 "WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy." Pubmed 1.58E-05 1.00E+00 6.13E-03 7.75E-02 11 35 "STMN2,L1CAM,MAPT,NEFH,PAX6,PPP2R2B,WDR37,WDR47,DMXL2,ZNF106,HIRA" Pubmed 15640798 Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 21435555 Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "SLIT2,DLX1,EBF1,L1CAM,MEIS2,ROBO1,ROBO2" Pubmed 9179496 Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "HDAC4,ELMO1,C2CD2L,PTPRT,CUX2,CLIP2,TRIM9" Pubmed 19948886 Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "CALB2,TUBB3,SEMA4D,GAD1,MAP2,PLXNB1,RELN" Pubmed 22632726 Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "SEMA6A,PLXNA4,SEMA3D,NRCAM,SEMA6D,ZIC2,SEMA3B" Pubmed 12771190 "SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion." Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "PDCD6IP,EGFR,PTK2B,SH3KBP1,MASP1,PTK2,TUBA1A" Pubmed 19936227 Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "CALB1,CALB2,ERBB2,TUBB3,MYO7A,NTRK2,NTRK3" Pubmed 19605412 Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "ACHE,GAD1,MAP2,NPY,ARX,SST,SATB2" Pubmed 22768092 The biochemical anatomy of cortical inhibitory synapses. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "GPHN,NBEA,GABRA3,GABRB3,GABRG1,GABRG2,NLGN3" Pubmed 18940588 Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Pubmed 1.73E-05 1.00E+00 6.59E-03 8.33E-02 7 14 "LHX2,ETV1,TUBB3,L1CAM,NEFH,RORB,CUX2" Pubmed 12223406 MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "TUBB3,MAP2,MAPK3,MAPK9,MAPK12,MAP3K12" Pubmed 15964765 Differential expression of individual gamma-protocadherins during mouse brain development. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "PCDHGB4,CDH2,PCDHGC3,PCDHGC5,PCDHGB6,PCDHGA4" Pubmed 17568776 Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALM1,CAMK2A,CAMK2G,KRIT1,RCHY1,UBC" Pubmed 19616129 Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALB1,TUBB3,GLUL,PAX6,STX1A,PRDM8" Pubmed 21491429 PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-? activation in mouse models of Down syndrome. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALB1,CALB2,CAMK2A,CAMK2G,TUBB3,MAP2" Pubmed 15385616 The Tlx gene regulates the timing of neurogenesis in the cortex. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALB2,TUBB3,MAP2,PAX6,SALL1,NR2E1" Pubmed 22806269 CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALB1,CALB2,TUBB3,MBP,RELN,CDK5RAP2" Pubmed 27810937 Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CPEB2,TUBB3,NEFH,CPEB3,CPEB4,TACR1" Pubmed 27170656 Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Pubmed 1.85E-05 1.00E+00 6.91E-03 8.73E-02 6 10 "CALB1,CALB2,CELSR3,PAX6,RELN,FZD3" Pubmed 15858069 Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. Pubmed 1.88E-05 1.00E+00 6.97E-03 8.81E-02 9 24 "FZD9,LHX2,CRYM,EMX2,EPHB1,TUBB3,GRIK4,KITLG,RELN" Pubmed 26857994 Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Pubmed 1.88E-05 1.00E+00 6.97E-03 8.81E-02 9 24 "CLTC,NBEA,MEIS2,NTRK2,NTRK3,RET,SYT1,UCHL1,MEIS3" Pubmed 27480238 SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Pubmed 1.88E-05 1.00E+00 6.97E-03 8.81E-02 9 24 "LRFN2,LRFN1,CASK,DLGAP1,GRIA2,MAPK3,LRFN5,SYN1,SYP" Pubmed 17461779 Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Pubmed 2.04E-05 1.00E+00 7.50E-03 9.49E-02 8 19 "CLTC,CPS1,TUBA1B,DHRS4,MAPKAP1,MLST8,RICTOR,TUBA1A" Pubmed 23895693 Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Pubmed 2.04E-05 1.00E+00 7.50E-03 9.49E-02 8 19 "ETV1,TUBB3,ALDH1L1,GLUL,PAX6,S100B,SATB2,DICER1" Pubmed 16168404 Gli3 is required for the specification and differentiation of preplate neurons. Pubmed 2.04E-05 1.00E+00 7.50E-03 9.49E-02 8 19 "AXIN2,NUMB,CALB2,STMN2,MAP2,PAX6,RELN,PARD3" Pubmed 17916349 A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Pubmed 2.04E-05 1.00E+00 7.50E-03 9.49E-02 8 19 "ACHE,AXIN2,NRP2,CDH2,TUBB3,GRIK4,MEIS2,PAX6" Pubmed 24721909 Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Pubmed 2.11E-05 1.00E+00 7.76E-03 9.81E-02 13 49 "LRIG1,TM9SF4,MAD2L2,MYO5A,MYO6,MYO7A,DUSP26,PPP3CA,CYBC1,OXR1,WDR37,RPGRIP1L,HIRA" Pubmed 20306291 A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Pubmed 2.15E-05 1.00E+00 7.82E-03 9.89E-02 10 30 "TMCC3,CARS,BOC,RGS17,FOXO3,IDH3A,IRX1,RXRA,FERMT1,PDZRN3" Pubmed 14973295 Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Pubmed 2.15E-05 1.00E+00 7.82E-03 9.89E-02 10 30 "SYT13,PTCH2,DLX1,EBF1,MSTN,GLI2,SHISAL1,MAPT,NELL2,PTCH1" Pubmed 19054571 Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Pubmed 2.15E-05 1.00E+00 7.82E-03 9.89E-02 10 30 "ADAM15,SEMA3D,ADAM28,ADAM22,NEFH,RELN,PCDHA3,WNT7A,FZD3,RTN4" Pubmed 23400010 Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Pubmed 2.33E-05 1.00E+00 8.47E-03 1.07E-01 16 71 "TNRC6C,ARRB1,JAZF1,COX4I1,SLC35F1,SEC31B,GRIN3A,IQGAP2,PPARGC1A,IGF1,MEF2C,WDR37,PHLDB1,LINC00511,STOX2,ZDHHC20" Pubmed 20877624 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. Pubmed 2.37E-05 1.00E+00 8.57E-03 1.08E-01 98 926 "ACADM,AS3MT,METAP1D,AK2,ABCD2,BBOX1,AMT,ALDH7A1,BCS1L,BID,LDHD,NFS1,TBRG4,LETMD1,COX4I1,CPS1,CS,SNPH,EARS2,DBT,EXOG,SLC25A18,FIS1,TMTC1,AASS,ELN,COQ7,MRPL37,MRPL10,DNAJC27,FECH,ATP5PD,COQ5,APOPT1,PRELID3A,GALC,MTHFD2,ACSS1,GATM,ALDH1L1,NFU1,GFER,DHRS4,AIFM3,GPT2,GPD2,TDRKH,COQ10A,HMGCL,CPT1C,IDH3A,IDH3B,IBA57,SFXN5,PACRG,ALDH1L2,NME4,OGG1,OPA1,ETFRF1,DUSP26,SLC25A23,MTRF1L,SEPT4,POLG,TATDN3,FITM2,PRODH,NDUFS7,ACSM5,QDPR,SLC25A48,OXR1,MRPS18A,SLC25A36,SUGCT,PTGR2,DGLUCY,SARS,SCP2,FOXRED1,SHMT2,NUBPL,MTERF2,SLC22A4,OGDHL,ADHFE1,IQCE,TK2,PDSS1,AMACR,TST,BCL2L13,MTCH1,CCDC136,NT5M,PDSS2,MRPL47" Pubmed 10737800 Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Pubmed 2.37E-05 1.00E+00 8.57E-03 1.08E-01 61 508 "FMNL2,TMCC3,MTUS1,TAOK1,CDC42BPA,PDE8B,EIF4G3,KIF1A,CARMIL3,AZGP1,MTMR2,CACNA1A,KALRN,CAMK2A,ISPD,ARHGEF2,MYL6B,FBXO7,PDE4DIP,ARHGAP32,DBI,ABCC5,HIPK3,SUGP2,TENM1,GMPR2,FLT1,AFF2,NOP56,PDLIM5,ABLIM2,ZNF44,HIGD1B,TNRC6A,KAT7,USP51,AGFG1,KLHL23,VWA2,NOVA1,ENPP2,DUSP15,RIC8B,NEK11,ATP8B4,FAM102A,R3HDM2,EPC1,RCOR3,KDM4B,ZSWIM8,ARHGAP26,VPS13A,SZT2,PCDHGA11,PCDHA1,ASXL3,TNS1,ELP5,ZIC1,ZNF225" Pubmed 12466305 "Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set." Pubmed 2.38E-05 1.00E+00 8.57E-03 1.08E-01 23 128 "CLDN10,CDC25B,CREM,PDE4DIP,DCAF4,DMD,DNM1L,EGFR,VPS13B,SYNCRIP,ANKFY1,CGREF1,MSANTD4,ITGA7,LIMS1,ZFYVE27,P2RX7,SEPT4,C19orf57,PRKAR1B,PBRM1,MCF2L,ENHO" Pubmed 12107410 "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants." Pubmed 2.38E-05 1.00E+00 8.57E-03 1.08E-01 21 111 "ADD1,TAOK1,ATP2B2,COL9A1,NCOR2,F5,FOXO3,FLT1,SYT17,CNOT4,PAX6,ENPP2,POLR2F,ATXN2,AMBRA1,SYBU,SEC31A,TMCC1,ZSWIM8,CEP68,TEK" Pubmed 22311982 Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "DPP10,DPP6,KCND2,KCNIP3" Pubmed 8743987 The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CACNB4,IGF1,KITLG,TMPO" Pubmed 8631898 Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "MAP2,MAP4,MAPT,MARK1" Pubmed 10428811 A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ARHGEF7,ARHGEF6,GIT2,GIT1" Pubmed 14654075 Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CSF1,CSF1R,KIT,KITLG" Pubmed 20849899 Role of TPPP/p25 on ?-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "SNCAIP,TPPP,SIRT2,SNCA" Pubmed 17182677 Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "KAT8,KAT7,KAT6B,KAT6A" Pubmed 24722207 Overexpression of LARGE suppresses muscle regeneration via down-regulation of insulin-like growth factor 1 and aggravates muscular dystrophy in mice. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "LARGE1,FKTN,IGF1,LAMA2" Pubmed 21217699 Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "KAT8,MSL3,MSL1,KANSL1" Pubmed 12815063 Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "FGF1,FGF12,FGF14,FGFR3" Pubmed 9895385 Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "EDN3,EDNRB,RET,UCHL1" Pubmed 27626661 SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CAST,ERC2,BRSK1,ERC1" Pubmed 8663089 Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ADD1,CALM1,SPTAN1,SPTB" Pubmed 10336464 Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "AP2A1,CLTC,DNM1,EPN2" Pubmed 10066790 "AP-4, a novel protein complex related to clathrin adaptors." Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "AP4M1,AP4B1,AP4S1,AP4E1" Pubmed 23821748 Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "STX1B,SNAP25,STX1A,STXBP1" Pubmed 27182061 "Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes." Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ARHGEF7,ARHGEF6,GIT2,GIT1" Pubmed 22250198 "Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation." Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ADCY5,P2RY13,P2RX7,P2RY1" Pubmed 12942088 CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "AP2A1,NUMB,DPYSL2,L1CAM" Pubmed 10662501 Structural and functional evolution of the L1 family: are four adhesion molecules better than one? Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CHL1,L1CAM,NRCAM,NFASC" Pubmed 14593108 Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ANK2,SLC8A1,SPTAN1,SPTB" Pubmed 21149567 Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "DNM1L,FIS1,OPA1,MFF" Pubmed 18854160 A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CDC42BPA,LURAP1,CDC42BPB,MYO18A" Pubmed 27895162 Cannabinoid Receptor Interacting Protein 1a Competition with ?-Arrestin for CB1 Receptor Binding Sites. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "ARRB1,ARRB2,CNR1,CNRIP1" Pubmed 1374350 Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CSF1,CSF1R,KIT,KITLG" Pubmed 7509919 "The ligand-receptor interactions of the endothelin systems are mediated by distinct ""message"" and ""address"" domains." Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 25644714 Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner. Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "CAMK2A,CAMK2B,RASGRF1,VLDLR" Pubmed 15454437 Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Pubmed 2.52E-05 1.00E+00 8.60E-03 1.09E-01 4 4 "DPP10,DPP6,KCND1,KCND2" Pubmed 10591208 The DNA sequence of human chromosome 22. Pubmed 2.57E-05 1.00E+00 8.73E-03 1.10E-01 41 299 "SYN3,ELFN2,MTMR3,CACNA1I,P2RX6,LARGE1,FBXO7,FAM19A5,TMEM184B,SULT4A1,PICK1,CRYBB1,CSNK1E,PPP6R2,TOM1,TUBA8,CSDC2,GGT5,MCHR1,GSTT2,PACSIN2,MGAT3,ZDHHC8,POLR2F,PPARA,CASTOR1,KCTD17,MAPK12,SBF1,PEX26,SEPT3,KIAA0930,CABIN1,RASD2,TST,OSBP2,BCL2L13,ZNF74,POLR3H,TFIP11,HPS4" Pubmed 24332808 PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Pubmed 2.62E-05 1.00E+00 8.88E-03 1.12E-01 45 340 "ADD1,AP2A1,AP2A2,KCNAB2,CCAR2,BLM,CCNH,ARHGEF2,CLTC,SMARCAL1,RBM39,MATR3,INTS1,ELMSAN1,DDX46,EGFR,POLR1B,SYNCRIP,SMC2,CELF1,TCERG1,ZNF638,DIDO1,PSIP1,MAP4,MOV10,HNRNPM,XRN1,EXOSC10,RPL15,RMI1,SMARCC2,LIMCH1,SPTAN1,RBM26,MPRIP,DNAJC9,COBL,TMPO,TPM2,UBC,WRN,INTS3,RTN4,HNRNPA3" Pubmed 18625063 FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Pubmed 2.76E-05 1.00E+00 9.34E-03 1.18E-01 9 25 "EMX2,TUBB3,FGFR1,FGFR3,GAD1,MEF2C,MEST,PAX6,RELN" Pubmed 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 2.90E-05 1.00E+00 9.63E-03 1.22E-01 49 383 "APC,ARRB1,ARRB2,CHRD,NCOA1,RIPK1,BMP7,BMPR1B,NOG,CNTFR,CRHBP,CSF1,CSF1R,DLX1,EGFR,EGR3,FGF1,FGFR1,FGFR3,FLT1,DLL3,MSTN,GHR,PPARGC1A,GLI2,MCHR1,IRAK3,IGF1,IL6R,IL6ST,LIFR,SMAD1,MEF2C,NTRK2,NTRK3,P2RX7,PPARA,MAPK3,PTCH1,PTH1R,PTN,RXRA,SPP1,TCF4,THRA,HEY1,TLR4,PIK3R5,WNT7A" Pubmed 22076636 Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Pubmed 2.97E-05 1.00E+00 9.63E-03 1.22E-01 10 31 "CHRD,BMP7,NOG,SLIT2,SEMA3D,FGFR1,FGFR3,PTCH1,UNC5B,SEMA3B" Pubmed 20308569 Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Pubmed 2.97E-05 1.00E+00 9.63E-03 1.22E-01 10 31 "AXIN2,NRP2,CALB2,ETV1,GRIK4,SMAD1,SMAD9,MEF2C,MAPK3,CUX2" Pubmed 19666558 Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Pubmed 2.97E-05 1.00E+00 9.63E-03 1.22E-01 10 31 "CLTB,CLTC,DNM1,HEYL,RBPJ,OCRL,HES6,EPN2,SYT1,HEY1" Pubmed 10712642 "Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain." Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "STMN1,MAP2,SNAP25,STX1A,SYP" Pubmed 20053908 Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "BOC,CDON,EPHB1,L1CAM,ZIC2" Pubmed 16514356 Expression of olig2 in retinal progenitor cells. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,CALB2,TUBB3,GLUL,NEFH" Pubmed 9611234 "The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70." Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "NCOR1,NR1D2,TAF6,TAF9,SIN3B" Pubmed 8999968 Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "STX2,STX1B,SNAP25,STX1A,SYT1" Pubmed 21688288 Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,SLIT2,TUBB3,ROBO1,ROBO2" Pubmed 11856531 Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,ETV1,MAP2,RELN,VLDLR" Pubmed 19710317 Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,CALB2,MAP2,RELN,VLDLR" Pubmed 24987331 "Altered GABAergic markers, increased binocularity and reduced plasticity in the visual cortex of Engrailed-2 knockout mice." Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,GAD1,NPY,SST,SLC17A7" Pubmed 17376969 Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB2,ETV1,GAD1,SST,CUX2" Pubmed 22376909 Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "DLX1,EGFR,ERBB4,GAD1,RELN" Pubmed 21765815 Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "NRP2,CCK,NRN1,NELL2,TCF12" Pubmed 9341169 Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "AMPH,BIN1,SYNJ1,DNM1,SH3GL3" Pubmed 3402356 A survey of neurological mutant mice. II. Lipid composition of myelinated tissue in possible myelin mutants. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "QKI,GALC,LAMA2,MBP,PMP22" Pubmed 12764029 Increase in reelin-positive cells in the marginal zone of Pax6 mutant mouse cortex. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CALB1,CALB2,EMX2,PAX6,RELN" Pubmed 10810084 Comparative genome mapping in the sequence-based era: early experience with human chromosome 7. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "SEPT7,DOCK4,RASA4,ETV1,ICA1" Pubmed 22138645 ?2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "CHN1,CHN2,DPYSL2,TUBB3,MAP2" Pubmed 16722236 The role of SNARE proteins in trafficking and function of neurotransmitter transporters. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "GAD1,CPLX1,SNAP25,STX1A,STXBP1" Pubmed 11148209 The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "BCAS1,DYNLL1,DLGAP1,DYNC1I1,MYO5A" Pubmed 18703708 Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 19713751 Proteomic analyses of native brain K(V)4.2 channel complexes. Pubmed 3.02E-05 1.00E+00 9.63E-03 1.22E-01 5 7 "DPP10,DPP6,KCND2,KCNIP3,KCNIP1" Pubmed 19320733 Pigmentation-related genes and their implication in malignant melanoma susceptibility. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "EDNRB,VPS13B,KIT,MITF,MYO5A,MYO7A,MGRN1" Pubmed 17356169 Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "PLXNA4,DLX1,PLXNC1,TUBB3,NPTX1,NPTX2,PLXNB1" Pubmed 17482548 LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "TUBB3,STRADA,BRSK1,L1CAM,MAP2,MAPT,RELN" Pubmed 23817546 Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "NUMB,CALB2,CDH2,TUBB3,PAX6,RELN,ZIC1" Pubmed 18385258 Dynamic regulation of the expression of neurotrophin receptors by Runx3. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "CALB1,CALB2,NTRK2,NTRK3,RET,SST,SLC17A7" Pubmed 12571103 Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "ACHE,DLX1,ETV1,PPP1R1B,MEIS2,PAX6,NR2E1" Pubmed 18224708 Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "CALB2,CDH2,EGFR,L1CAM,PAX6,STX1B,STX1A" Pubmed 16007083 "Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy." Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "CALB1,CALB2,DLX1,GAD1,NPY,RELN,SST" Pubmed 20619750 ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "CALB1,ETV1,TUBB3,NEFH,PAX6,PARD3,TP53BP2" Pubmed 21745462 Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "PRX,SPTBN4,CDH2,CNTN1,CNTNAP2,DRP2,NRCAM" Pubmed 23821580 Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "NRP2,SLIT2,ENO2,NCAM2,ROBO1,ROBO2,S100B" Pubmed 23454273 Role for Lhx2 in corticogenesis through regulation of progenitor differentiation. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "LHX2,ETV1,TUBB3,PAX6,RORB,CUX2,HEY1" Pubmed 22578469 Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Pubmed 3.05E-05 1.00E+00 9.63E-03 1.22E-01 7 15 "CALB1,CALB2,FGFR1,GAD1,RELN,ZIC1,ZIC2" Pubmed 16385451 A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Pubmed 3.17E-05 1.00E+00 9.97E-03 1.26E-01 52 416 "AS3MT,SEMA4G,CAMK2G,CH25H,ARHGAP22,SEC31B,CREM,SPOCK2,RHOBTB1,FAM107B,CHRDL1,CNNM1,OPTN,CHST15,POLL,ATE1,KNDC1,HECTD2,PIK3AP1,ZFYVE27,MXI1,SFR1,VWA2,PFKFB3,CCSER2,CNNM2,PSD,WBP1L,PTPRE,CRTAC1,RET,MCMBP,CPEB3,HKDC1,SEPHS1,TET1,EPC1,OGDHL,CABCOCO1,ZSWIM8,UNC5B,LHPP,PBLD,MMS19,DNMBP,ZEB1,SIRT1,PARD3,KAT6B,FAM13C,MARCH8,JMJD1C" Pubmed 15648052 Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. Pubmed 3.19E-05 1.00E+00 9.97E-03 1.26E-01 8 20 "ATP1A1,ATP1A3,CAMK2A,DBN1,DPYSL2,ENO2,MBP,STX1B" Pubmed 20696379 Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Pubmed 3.19E-05 1.00E+00 9.97E-03 1.26E-01 8 20 "SLIT2,LHX2,ETV1,TUBB3,MSI1,PAX6,ROBO1,ROBO2" Pubmed 23312517 Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Pubmed 3.19E-05 1.00E+00 9.97E-03 1.26E-01 8 20 "NRP2,CALB2,ERBB4,GAD1,NPY,UNC5B,SST,FLRT2" Pubmed 19079260 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Pubmed 3.19E-05 1.00E+00 9.97E-03 1.26E-01 8 20 "SH2B1,DGKG,NEGR1,KCTD15,BDNF-AS,TRA2B,FAIM2,CHST8" Pubmed 11322959 "The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number." Pubmed 3.19E-05 1.00E+00 9.97E-03 1.26E-01 8 20 "PCDHB17P,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3" Pubmed 15172686 Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. Pubmed 3.23E-05 1.00E+00 1.01E-02 1.27E-01 12 44 "C1QTNF3,ALCAM,FAM19A5,CRYM,SNAP91,SPSB4,GCNT2,RABL2A,PCDH9,SALL1,SMARCD3,SOX11" Pubmed 22094256 A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. Pubmed 3.36E-05 1.00E+00 1.05E-02 1.32E-01 16 73 "PRX,SRSF11,FOXO3,PPARGC1A,MSL3,CLASRP,SRSF12,CASC3,TRA2B,POGZ,ANKRD12,ZEB1,SIRT1,SYNPO2,SSBP2,EIF4ENIF1" Pubmed 20467437 Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. Pubmed 3.52E-05 1.00E+00 1.09E-02 1.38E-01 67 581 "TAOK1,MAGEE2,BID,BLM,FUBP1,PTBP2,HIP1R,ARHGEF1,ARHGEF2,SEPT7,LRWD1,COPB2,SRSF11,SEC31B,RBM39,NCOR2,SEC24C,INTS1,DCTN1,GSDME,DDX46,DOCK2,PDCD6IP,DNM1L,SRRM1,TUBA1B,TUBB3,MED12L,SEC23B,SYNCRIP,DCTN2,SMC2,SEPT9,TUBGCP4,ARFIP1,BRD8,ZNF638,DDX19B,IPO5,LIMS1,MPP2,HNRNPM,NF1,OLA1,PLEC,EXOSC10,KANSL1,KIF27,PUF60,SCAF8,KIF21A,FERMT1,SMARCA4,SMARCC2,SPTAN1,MTCL1,EXOC7,CLASP1,TMPO,METTL3,TUBB1,SMARCAD1,INTS3,FIP1L1,DOCK8,HNRNPA3,LAS1L" Pubmed 24529757 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. Pubmed 3.52E-05 1.00E+00 1.09E-02 1.38E-01 18 89 "TMEM132B,KCTD16,ALCAM,ATP2B2,BMPR1B,NOG,ABCG1,RGS6,TMEM132E,EPB41,ERBB4,STON1,METTL21A,LAMA2,MASP1,MRAS,NFASC,SYNPO2" Pubmed 19454010 In vitro nuclear interactome of the HIV-1 Tat protein. Pubmed 3.54E-05 1.00E+00 1.10E-02 1.39E-01 30 195 "MTA3,EP400,DYNLL1,CCNT1,AHCTF1,RBM39,MATR3,MYEF2,DDX46,EEF1D,ERCC2,TUBB3,RACK1,NOP56,SMC2,STAU2,ZNF638,KAT7,DDX19B,HNRNPM,RBBP6,DPF2,PBRM1,DHX30,SMARCA4,SMARCC2,TMPO,TUBB2A,UBTF,XPO1" Pubmed 19911011 Mutation of ARHGAP9 in patients with coronary spastic angina. Pubmed 3.74E-05 1.00E+00 1.15E-02 1.45E-01 11 38 "ARHGEF1,ARHGEF2,CHN2,NGEF,ARHGEF6,DLC1,ARHGEF9,MCF2L,ARHGAP9,TIAM1,TRIO" Pubmed 17360631 Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "KIF1A,KIF5A,MAP2,SYP,SYT1,TUBA1A" Pubmed 12456676 "Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1." Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "AMPH,BIN1,SYNJ1,DNM1,SH3GL3,SYN1" Pubmed 10325223 Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "BMP7,CALB2,LHX2,EMX2,GAD1,MAP2" Pubmed 22573669 Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CALB1,DCLK1,APC2,TUBB3,NTRK2,RELN" Pubmed 15837802 Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "ATP1A3,EGR3,PRPH,SSTR2,HEY1,TMEM178A" Pubmed 25374362 The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CADPS,CPLX2,CPLX1,SNAP25,STX1A,SYT1" Pubmed 15117958 90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "FGFR1,PIK3R1,RTN1,SH3BP2,SLA,TNS2" Pubmed 9882498 Synapse formation by hippocampal neurons from agrin-deficient mice. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "DLGAP1,SV2B,GPHN,GABRB3,SYN1,SYP" Pubmed 19302145 Secreted TARSH regulates olfactory mitral cell dendritic complexity. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CAMK2B,PLPPR4,PRUNE2,MEF2C,RGS4,PCDH20" Pubmed 15273690 Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "NUMB,NUMBL,TUBB3,MSI1,PAX6,RELN" Pubmed 18562598 Molecular mechanisms controlling midline crossing by precerebellar neurons. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CALB1,SLIT2,ETV1,PAX6,ROBO1,ROBO2" Pubmed 19906969 Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "NRP2,SLIT2,TUBB3,GNAO1,ROBO1,ROBO2" Pubmed 15882093 Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "DLX1,TUBB3,PPP1R1B,PAX6,ROBO1,SOX3" Pubmed 23478408 Planar cell polarity genes control the connectivity of enteric neurons. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CALB2,CELSR3,TUBB3,KIT,RET,FZD3" Pubmed 25030704 Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "SLIT2,CNR1,L1CAM,MAPT,ROBO1,ROBO2" Pubmed 11753414 Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "SNAP25,STX1A,STXBP1,SYN1,SYP,SYT1" Pubmed 12091317 Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Pubmed 3.83E-05 1.00E+00 1.15E-02 1.45E-01 6 11 "CALB2,LHX2,EMX2,L1CAM,MAP2,RELN" Pubmed 26439863 Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef. Pubmed 3.94E-05 1.00E+00 1.18E-02 1.49E-01 23 132 "ELFN2,LRFN1,SCARB1,ARHGEF2,NRXN3,NECTIN3,CSF1,GAPVD1,CD99L2,EIF4G1,CD320,FGFR1,SEMA4D,ADGRA3,NCKAP1L,IPO5,PCDH9,NCR3LG1,RAP1GDS1,PCDHGB1,VLDLR,TMEM237,SLC38A1" Pubmed 23643363 Chromatin regulation by BAF170 controls cerebral cortical size and thickness. Pubmed 3.95E-05 1.00E+00 1.18E-02 1.49E-01 9 26 "PROM1,ETV1,TUBB3,PAX6,RORB,SMARCA4,SMARCC2,SATB2,CUX2" Pubmed 22232070 "Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1." Pubmed 3.95E-05 1.00E+00 1.18E-02 1.49E-01 9 26 "AXIN2,TUBB3,FGFR3,GLI2,RBPJ,MAP2,MSI1,PAX6,NR2E1" Pubmed 18448089 Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Pubmed 3.95E-05 1.00E+00 1.18E-02 1.49E-01 9 26 "AXIN2,CALB1,CALB2,ETV1,GAD1,MAP2,RELN,RORB,CUX2" Pubmed 10843805 A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5. Pubmed 4.05E-05 1.00E+00 1.21E-02 1.52E-01 10 32 "CACNA2D1,CD38,CRMP1,DPP6,SEMA3D,FGFR3,KCNH2,KCNK3,QDPR,SLC30A3" Pubmed 22926577 "Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis." Pubmed 4.13E-05 1.00E+00 1.22E-02 1.55E-01 12 45 "NDRG2,DYNLL1,CALM1,SYNGR3,SEC16A,TTBK1,PADI2,MBP,MAPKAP1,ZNF430,SIRT2,CCDC14" Pubmed 8889549 "Generation and analysis of 280,000 human expressed sequence tags." Pubmed 4.13E-05 1.00E+00 1.22E-02 1.55E-01 44 336 "ADD2,SYT13,SMIM29,DST,CFL2,FOXN3,SNCAIP,PDE4DIP,DAPK1,SPATA2,TMCC2,EGR3,EIF1,AMOTL2,USP21,ZMAT1,WASHC2A,COPS8,GPR34,PTPRT,HLF,ZNF491,HP,IL6R,ZNF92,SH3KBP1,RFX2,PBRM1,DGLUCY,MAPK12,BTBD3,KIF13A,ZNF415,TMCC1,SPART,DNMBP,SIK3,CYB561A3,PARD3,SYNPO2,FAM155A,PCDH20,ZNF138,FAM47E" Pubmed 15592455 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Pubmed 4.23E-05 1.00E+00 1.25E-02 1.58E-01 43 326 "ALK,KCNAB2,BID,FUBP1,CARS,C1orf52,SEPT7,CDC42BPB,ENTPD4,ZFYVE16,IST1,GIT2,DNM1,DOCK2,HIPK3,EIF4G1,TNK2,EIF1,ENO2,TUBA1B,RACK1,BAIAP2,MPP6,CRCP,RNPS1,SYNPO,GIT1,DBNL,PIK3R1,PKM,PLEC,RASA3,ELMO2,FNBP1,ERBIN,STXBP1,TACC1,DICER1,VAV1,TBC1D15,CFAP298,ZNF24,FXR1" Pubmed 20398908 Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Pubmed 4.51E-05 1.00E+00 1.33E-02 1.68E-01 15 67 "DGCR6,ACHE,FZD9,NRXN3,GABBR1,DISC1,GRIA2,GRM8,PLCD1,PPP3CC,PRODH,S100B,NLGN1,TACR1,TFIP11" Pubmed 22321011 Protein phosphatase 1? interacting proteins in the human brain. Pubmed 4.51E-05 1.00E+00 1.33E-02 1.68E-01 15 67 "CEP126,CLTC,MAP4K4,CNTN1,AATK,SNCAIP,PHACTR3,DCTN1,NDP,ZNF827,GLIPR1L2,STAU1,KANK1,TP53BP2,JPH3" Pubmed 12466855 A gene expression map of human chromosome 21 orthologues in the mouse. Pubmed 4.51E-05 1.00E+00 1.33E-02 1.68E-01 25 151 "BACH1,SYNJ1,CFAP410,CBR1,CBS,CLTC,C2CD2,ABCG1,RCAN1,VPS26C,IGSF5,PAXBP1,LSS,N6AMT1,NCAM2,PCBP3,SETD4,HUNK,S100B,SAMSN1,DIP2A,TIAM1,TRPM2,TTC3,CFAP298" Pubmed 18554416 Identification of transcripts with enriched expression in the developing and adult pancreas. Pubmed 4.62E-05 1.00E+00 1.36E-02 1.72E-01 66 575 "VWA5B2,SPARCL1,ALCAM,LTBP4,SYT13,APLP1,ARHGDIG,CADPS,ATP2A2,MYOM1,RGS11,BTK,HAP1,CCK,CHGB,MAGED1,ZNF385A,AKAP12,COQ7,VPS26C,SCARA3,VTI1B,EFCAB2,UFM1,ST6GALNAC3,SARAF,SDCBP2,GCK,TCERG1,LOXL3,FERMT2,GPD2,CCDC184,GRIK5,GSN,HBA1,KIFC3,SYTL4,PACRG,MEST,MOV10,MYT1,NACA,SFR1,PAX6,PCSK1,PDE1C,PGAM2,PPP1R1A,DPF2,ZDHHC4,MRPS18A,LGI2,HES6,ARX,FERMT1,CDK5RAP2,SPP1,APOM,ARC,DICER1,BEX4,TTC3,RPL7L1,MTCH1,ZNF24" Pubmed 21386911 "Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways." Pubmed 4.69E-05 1.00E+00 1.38E-02 1.74E-01 28 179 "ADCY8,CACNB4,LY86,COL9A1,RBM39,SNCAIP,RASSF2,PIPOX,EYA1,C2orf88,CGREF1,ALDH1L1,GPD1,CCDC184,IGF1,AQP11,KITLG,NPY,GNG2,SERPINI1,PTN,PID1,DZIP1,APOM,VWCE,SYNPO2,VLDLR,SEMA3B" Pubmed 22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Pubmed 4.81E-05 1.00E+00 1.40E-02 1.78E-01 18 91 "XKR4,PTCHD1,DAPK1,SPOCK3,DYNC1I1,MAMLD1,IRAK4,TENM1,CNTRL,KCND2,TMEM110-MUSTN1,COL28A1,P2RY1,ZNF827,PDE4D,DCHS2,BCAS3,SGK1" Pubmed 16987518 Disruption of parental-specific expression of imprinted genes in uniparental fetuses. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "SGCE,GRB10,MEST,NNAT,MAGEL2,SNRPN,PEG10,MKRN3" Pubmed 23790753 SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "ETV1,TUBB3,BRSK1,MAPT,NEFH,NTRK3,MAPK3,SLC17A7" Pubmed 16330018 Brg1 is required for murine neural stem cell maintenance and gliogenesis. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "CALB2,TUBB3,MBP,MSI1,PAX6,RELN,S100B,SMARCA4" Pubmed 17065231 BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "BMPR1B,FGFR1,SMAD1,SMAD9,MAPK3,PTCH1,PTH1R,SPP1" Pubmed 20445055 Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "BMPR1B,CALB1,CALB2,ETV1,TUBB3,SMAD1,SMAD9,RORB" Pubmed 11060228 The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Pubmed 4.85E-05 1.00E+00 1.40E-02 1.78E-01 8 21 "CALB1,CALB2,DLX1,EBF1,PPP1R1B,GAD1,PAX6,PTN" Pubmed 20562864 Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Pubmed 4.86E-05 1.00E+00 1.41E-02 1.78E-01 17 83 "BCL7A,NSL1,ZNF585B,ZNF274,AHDC1,CBX1,CHAMP1,PPP2R5E,ZNF568,ZFP1,SMARCA4,POGZ,ZNF302,CBX5,ZNF45,ZNF195,SENP7" Pubmed 23752268 The functional interactome landscape of the human histone deacetylase family. Pubmed 4.88E-05 1.00E+00 1.41E-02 1.78E-01 39 287 "ACADM,PWWP2A,MTA3,ZNF687,PHF12,CCAR2,PLAA,ZNF521,NCOR1,NCOR2,APPL1,HDAC9,HDAC4,ELMSAN1,ZC3H11A,SEC16A,DNAJB6,FDFT1,NOP56,MIER3,IPO5,PAXBP1,ZNF827,ZSCAN2,USP47,PUF60,RCOR3,RBM34,TRERF1,MYCBP2,SYNE2,ANKRD12,TBL1X,SIN3B,DICER1,TMPO,TFIP11,EMSY,FIP1L1" Pubmed 19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Pubmed 4.88E-05 1.00E+00 1.41E-02 1.78E-01 11 39 "NCKAP5,FOXO3,MXI1,PCSK5,PDZRN4,RELN,SLC25A36,KCNIP1,NUBPL,CSMD1,ZIC1" Pubmed 18973680 Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Pubmed 4.92E-05 1.00E+00 1.42E-02 1.79E-01 38 277 "KDM5D,PCDH19,AMPH,CDC14B,SLC4A4,PROM1,IGDCC3,HAPLN1,GPSM1,DBT,MYEF2,FAM107B,CD99L2,PLEKHA1,SCARA3,AP4S1,RABL2A,CFAP126,INPP1,MEST,KITLG,PTOV1,NNAT,NPTX2,PCSK5,PPP1R1A,PTPRG,SLC25A36,SCN2B,LIMCH1,TROVE2,PHLDB1,ZC3H4,PDLIM2,RPL7L1,FLRT2,TBC1D15,MAP3K12" Pubmed 20362541 An Oct4-centered protein interaction network in embryonic stem cells. Pubmed 4.97E-05 1.00E+00 1.43E-02 1.81E-01 26 161 "MTA3,OGT,EP400,ZMYM4,ELMSAN1,MED12,KAT8,BRD8,RBPJ,KIF5A,CHAMP1,ING3,DPF2,PBRM1,SALL1,KANSL3,SMARCA4,SMARCC2,PEG10,POGZ,TAF6,TAF9,SATB2,CABIN1,EMSY,JMJD1C" Pubmed 12466854 Human chromosome 21 gene expression atlas in the mouse. Pubmed 5.05E-05 1.00E+00 1.44E-02 1.83E-01 25 152 "BACH1,SYNJ1,CFAP410,CBR1,CBS,C2CD2,ABCG1,RCAN1,VPS26C,IGSF5,PAXBP1,LSS,N6AMT1,NCAM2,PCBP3,SETD4,HUNK,S100B,SAMSN1,DIP2A,SLC37A2,TIAM1,TRPM2,TTC3,CFAP298" Pubmed 19549840 Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "CALB1,DLX1,TUBB3,PPP1R1B,NPY,PDPK1,SLC17A7" Pubmed 21518438 Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "HDAC9,EDIL3,FGFR3,ADAM22,P2RX7,PKD1,CPEB3" Pubmed 20064392 Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "CALB1,GFRA2,NEFH,NTRK2,NTRK3,RET,UCHL1" Pubmed 27984743 Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "SYNJ1,SLIT2,SHANK1,NBEA,RAPGEF6,SRRM4,VPS13C" Pubmed 8221886 Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "TUBB3,STMN2,KIT,KITLG,NTRK2,PRPH,RET" Pubmed 20808911 A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "DLGAP1,SLC12A6,NSG1,KIF5A,PALM,STAU1,SYT1" Pubmed 23136392 Frs2? enhances fibroblast growth factor-mediated survival and differentiation in lens development. Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "ALK,ETV1,NTRK2,NTRK3,PAX6,MAPK3,RET" Pubmed 28066179 "Distinct and Cooperative Functions for the Protocadherin-?, -? and -? Clusters in Neuronal Survival and Axon Targeting." Pubmed 5.10E-05 1.00E+00 1.44E-02 1.83E-01 7 16 "CALB1,CALB2,TUBB3,MAP2,PCDHB15,PCDHB4,SLC17A7" Pubmed 26002199 The Repeat Expansion Diseases: The dark side of DNA repair. Pubmed 5.45E-05 1.00E+00 1.54E-02 1.95E-01 10 33 "CACNA1A,DMPK,AFF2,NOP56,ZNF713,PPP2R2B,ATXN2,ATXN7,TCF4,JPH3" Pubmed 15174051 "An investigation into the human serum ""interactome""." Pubmed 5.54E-05 1.00E+00 1.56E-02 1.98E-01 26 162 "ADRA1B,AMPD3,APOC1,APOC2,IGDCC4,AP1M1,CACNA1I,CST3,FAM169A,DGKG,SACS,DMD,GABBR1,GSN,HBA1,HP,MIA2,PDE4B,PDZRN4,QDPR,CAMTA1,OBSL1,DICER1,AP4E1,TIAM1,GJC2" Pubmed 27076431 Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. Pubmed 5.57E-05 1.00E+00 1.56E-02 1.98E-01 9 27 "ASIC1,SMAD1,SMAD9,NEFH,NTRK2,NTRK3,RET,SALL1,CUX2" Pubmed 18649358 Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. Pubmed 5.57E-05 1.00E+00 1.56E-02 1.98E-01 9 27 "GALNT13,PKP4,GRIN3A,EPHB1,MYH3,KDM4C,PLCB1,MTCL1,SYNE1" Pubmed 22056141 Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions. Pubmed 5.57E-05 1.00E+00 1.56E-02 1.98E-01 9 27 "CALB2,TUBB3,MBP,PAX6,MAPK3,S100B,TSC1,TSC2,RICTOR" Pubmed 10574461 Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. Pubmed 5.66E-05 1.00E+00 1.59E-02 2.01E-01 16 76 "GALNT16,TMCC3,CADPS,CACNA1I,CACNA1G,HECTD1,CDC42BPB,KLHL3,NXPH3,CCSER2,MINDY2,ZC4H2,NDRG4,SPIRE1,SMARCAD1,TTC7A" Pubmed 19948975 Integrative predictive model of coronary artery calcification in atherosclerosis. Pubmed 5.69E-05 1.00E+00 1.59E-02 2.01E-01 33 229 "ADORA2A,ADRB2,AGT,AMPD2,APOC2,RGS9,C5,CBS,SCARB1,ABCG1,CTH,DMPK,EDN1,FEM1B,PLEKHA1,ELN,MRPL10,TLR7,F5,PRKAG2,GCK,PPARGC1A,HMGCR,IGF1,MYO7A,NFE2L2,PAX6,PDE4D,PLTP,PPARA,PRKAB2,TLR4,WRN" Pubmed 18464913 A genome-wide association study identifies protein quantitative trait loci (pQTLs). Pubmed 6.00E-05 1.00E+00 1.68E-02 2.12E-01 14 61 "OSBPL1A,ATP2A2,CNTN1,SACS,DOCK2,WDPCP,FAM49B,IL6R,PDZRN4,DIRAS2,CYBC1,KHDRBS2,ROBO1,ROBO2" Pubmed 22083510 Oct4 links multiple epigenetic pathways to the pluripotency network. Pubmed 6.05E-05 1.00E+00 1.69E-02 2.13E-01 29 191 "MTA3,TAOK1,OGT,ATP1A1,PTBP2,CNN3,NCOR2,MATR3,DBT,TCERG1,GLI2,PRRC2B,TOX2,IDH3B,LIMS1,AFDN,NACA,LAMA1,DPF2,PBRM1,SALL1,SCAF8,TET1,SMARCA4,SMARCC2,TMPO,TP53BP1,RTN4,JMJD1C" Pubmed 19490893 A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Pubmed 6.05E-05 1.00E+00 1.69E-02 2.13E-01 43 331 "ADCY8,MPDZ,PROM1,NAE1,CA12,USP6,CACNA2D2,CHN1,RCHY1,COPS4,DCTN4,CDKL3,FCGR1A,NOP56,WDR83,ZMAT1,TUBGCP4,FREM1,COPS8,DCLK2,DIDO1,MATN2,MID1,ADAM22,NEK1,NF1,SLC11A2,EXOSC10,RELN,FBXW7,EMID1,CCDC112,FRMPD1,WDR37,SNRPN,ZC3H13,TK2,UBTF,FLRT2,XPO1,NAV3,UBE3B,FBXO36" Pubmed 24997765 Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Pubmed 6.31E-05 1.00E+00 1.76E-02 2.22E-01 11 40 "APC,LDB2,AKAP12,KIF26A,SV2B,EPHB1,MBP,ERBIN,SATB2,CUX2,FLRT2" Pubmed 23375831 In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Pubmed 6.37E-05 1.00E+00 1.77E-02 2.24E-01 24 145 "MAP4K3,ARNTL,RASL11B,CNN3,ENTPD4,CNTNAP2,DLC1,MTHFD2,CACFD1,FAM107A,HMGCL,SCIN,SERPINI1,PKD1,SCHIP1,SEPT4,DGLUCY,ABLIM3,EPC1,TIMP4,LYPD6,ZFAND5,ACTR3B,NETO2" Pubmed 25631074 Analysis of HIV-1 Gag protein interactions via biotin ligase tagging. Pubmed 6.43E-05 1.00E+00 1.78E-02 2.25E-01 13 54 "ATP1A1,EIF4G1,EIF5,EPB41,EPB41L2,ATXN2L,MAP4,AFDN,HNRNPM,XRN1,RBM26,PRRC2C,TMPO" Pubmed 22266860 Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells. Pubmed 6.43E-05 1.00E+00 1.78E-02 2.25E-01 13 54 "MYH7B,CALM1,MYL6B,CDC42BPB,DBN1,TUBA1B,TUBB3,FHL1,MYO6,PLEC,CNTLN,TPM1,TPM2" Pubmed 23824909 Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Pubmed 6.49E-05 1.00E+00 1.79E-02 2.27E-01 47 374 "AK2,DPP10,RASL11B,BID,LRBA,PPT2,NECTIN3,TRIM69,AIF1L,ELMO1,FAM107B,PDCD6IP,COPS4,SH3YL1,EVL,EFCAB2,APOPT1,SPIN1,GNAO1,LPAR4,MUM1,HSPA1L,SCIN,METTL21A,STMN1,MAP4,DBNL,NDP,OLA1,ZNF655,PLEC,ZNF426,PSAT1,MAPK7,PSMA6,S100B,COPZ1,FUZ,PBLD,ALG1,PCDHGB2,WBP2,SSBP2,TOM1L2,WIPF1,CFAP298,NETO1" Pubmed 15102471 Bioinformatics and cellular signaling. Pubmed 6.61E-05 1.00E+00 1.82E-02 2.31E-01 27 173 "ARHGDIA,ARRB1,ARHGEF7,BTK,CAMK2A,CAMK2B,ARHGEF1,HDAC9,GIT2,ELMO1,PDCD6IP,DNAJB6,EIF4G2,COPS4,RACK1,SMC2,FYN,TRAF3IP2,IRAK3,IPO5,PIK3AP1,MEF2C,NFE2L2,PIK3R1,MAPK9,MAPK12,WIPF1" Pubmed 26831064 CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly. Pubmed 6.96E-05 1.00E+00 1.92E-02 2.43E-01 58 494 "OGT,TNRC6C,CCAR2,BARD1,BLM,SPAG9,SEPT7,LRRFIP1,COPB2,CLTC,RCHY1,AKAP12,SEC24C,MATR3,DCTN1,SEC16A,PDCD6IP,EEF1D,EIF4G1,TUBB3,RACK1,PRMT5,SEC24B,SEC23B,SYNCRIP,FLNC,NOP56,PDLIM5,SEPT9,TNRC6A,ATXN2L,HSPA1L,IPO5,MAP4,MOV10,NACA,HNRNPM,PKM,PLEC,EXOSC10,PCMTD2,RPL15,CLIP1,TRA2B,HSPA4L,CHD9,SEC31A,SMARCA4,SMARCC2,ERC1,SPTAN1,ITPRID2,STAU1,GPR161,TP53BP1,XPO1,HNRNPA3,AAAS" Pubmed 20875817 DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Pubmed 7.15E-05 1.00E+00 1.92E-02 2.43E-01 8 22 "BMPR1B,CALB1,CALB2,TUBB3,GLUL,SMAD1,SMAD9,PAX6" Pubmed 28334989 Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. Pubmed 7.15E-05 1.00E+00 1.92E-02 2.43E-01 8 22 "AXIN2,HEYL,MSTN,ITGA7,ITGAM,LAMA2,LAMA1,HEY1" Pubmed 25294941 ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Pubmed 7.15E-05 1.00E+00 1.92E-02 2.43E-01 8 22 "DYNLL1,PAX6,PTCH1,RFX3,IFT122,ATMIN,TP53BP1,IFT88" Pubmed 24626607 Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CALB2,ETV1,NPY,RORB,SST,CUX2" Pubmed 17329426 Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "SEMA6A,SLIT2,LHX2,GAD1,NPTX1,NPTX2" Pubmed 20018852 Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "OGT,KAT8,MSL3,MSL1,KANSL1,KANSL3" Pubmed 28826478 Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CACNA2D1,MBNL2,MBNL1,PPP3CA,PPP3CC,CLASP1" Pubmed 23217742 Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "ISPD,SLIT2,EDIL3,L1CAM,ROBO1,ROBO2" Pubmed 27399837 "Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility." Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "ESYT2,OSBPL8,EDIL3,SYT3,TMEM110-MUSTN1,SYT1" Pubmed 15457507 Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "NRP2,ERBB4,TUBB3,L1CAM,NCAM2,ROBO2" Pubmed 20419449 "Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people." Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "ADCY5,MADD,CRY2,DGKB,IGF1,AGMO" Pubmed 27707970 A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "EDIL3,ETV1,MAPT,NEFH,RET,S100B" Pubmed 11700294 Identification of epilepsy genes in human and mouse. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CACNA1A,CACNB4,CACNA2D2,ADGRV1,MYO5A,PMP22" Pubmed 15331610 The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "TUBA1B,TUBB3,TUBA8,TUBB2A,TUBB1,TUBA1A" Pubmed 28283561 Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "DISC1,KCNB1,L1CAM,PDE4A,PDE4B,SCN8A" Pubmed 16162939 Absence of Fyn and Src causes a reeler-like phenotype. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CALB1,CALB2,TUBB3,FYN,RELN,PTK2" Pubmed 14687546 Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "NUMB,CDH2,NUMBL,ETV1,TUBB3,RELN" Pubmed 23342162 Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "MTMR2,GAA,HAS2,PAX6,FAT4,SNCA" Pubmed 17803915 SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CASK,SNAP25,STXBP1,SYN2,SYP,UBC" Pubmed 16766712 Cellular patterns of transcription factor expression in developing cortical interneurons. Pubmed 7.21E-05 1.00E+00 1.92E-02 2.43E-01 6 12 "CALB2,DLX1,GAD1,ARX,SST,CUX2" Pubmed 18848646 Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Pubmed 7.25E-05 1.00E+00 1.92E-02 2.43E-01 10 34 "LRFN2,LRFN1,LRIG1,ADGRA3,LINGO1,NTRK2,NTRK3,LRRN3,LRFN5,LRRC24" Pubmed 18498732 Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves. Pubmed 7.25E-05 1.00E+00 1.92E-02 2.43E-01 10 34 "LDB2,ETV1,TUBB3,GFRA2,NEFH,NTRK2,NTRK3,MAPK3,PRPH,RET" Pubmed 20301500 Joubert Syndrome and Related Disorders Pubmed 7.25E-05 1.00E+00 1.92E-02 2.43E-01 10 34 "CC2D2A,KIAA0586,TMEM107,POC1B,CEP41,TMEM231,KIF7,ZNF423,RPGRIP1L,TMEM237" Pubmed 25615642 Galnt1 is required for normal heart valve development and cardiac function. Pubmed 7.25E-05 1.00E+00 1.92E-02 2.43E-01 10 34 "GALNT16,GALNT13,HAPLN1,VCAN,EGFR,GALNT15,SMAD1,MAPK3,GALNT10,ADAMTS9" Pubmed 29799838 Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. Pubmed 7.25E-05 1.00E+00 1.92E-02 2.43E-01 10 34 "HIP1R,RGN,YTHDC1,CNNM1,LRP1B,SLC11A2,PSAT1,SPATA7,TRPS1,ZNF711" Pubmed 19625176 PTEN identified as important risk factor of chronic obstructive pulmonary disease. Pubmed 7.39E-05 1.00E+00 1.95E-02 2.46E-01 47 376 "AXIN2,AMT,APAF1,APC,BARD1,BLM,CBR1,CBS,CCNH,CD86,SCARB1,CDC25B,CSF1R,RGS6,CTH,CYBB,MATR3,EDN1,EGFR,RGS17,ERBB2,ERCC2,MTHFD2,ALDH1L1,GHR,HMGCR,IGF1,IL6R,IL12A,LMO2,MEST,MSR1,MX1,MYO5A,NCF2,OGG1,P2RX7,ABCB1,MASP1,RET,RNASEL,FBXW7,RXRA,AMACR,WRN,XRCC4,SLC30A4" Pubmed 19741146 A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. Pubmed 7.51E-05 1.00E+00 1.95E-02 2.46E-01 18 94 "ARNTL,LHX2,TBPL1,E2F5,E2F6,GLUL,SOX21,MBP,MID1,NFIX,IRX1,RFX3,RXRA,ZKSCAN3,TCF4,TCF12,NSD1,NR2E1" Pubmed 11698390 Tubulin seeds alpha-synuclein fibril formation. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "TUBA1B,TUBB3,MAPT,SNCA,TUBA1A" Pubmed 16691566 Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "ACHE,CALB1,ETV1,PPP1R1B,L1CAM" Pubmed 23416450 EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "EGFR,MAP2,NTRK2,NTRK3,PAX6" Pubmed 11395011 Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "SLC12A6,GPHN,MAP2,SLC12A2,SLC12A4" Pubmed 19914172 KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "KIF26A,TUBB3,KIT,MAPK3,UCHL1" Pubmed 16618118 Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "CSNK1E,CSNK1G3,MAPT,SNCA,DBNDD2" Pubmed 17310244 Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "ARHGEF7,GIT2,EPHB1,GIT1,SYP" Pubmed 24327345 Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "DBN1,NEFH,SNAP25,SYN1,SYT1" Pubmed 20237162 "Chemerin, a novel adipokine in the regulation of angiogenesis." Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "PI16,EDIL3,GRM8,TRHDE,PTCH1" Pubmed 22216198 A genome-wide association study of the Protein C anticoagulant pathway. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "MYH7B,KCTD8,ELMO1,LINGO1,FRMD6" Pubmed 18454205 The secreted metalloprotease ADAMTS20 is required for melanoblast survival. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "VCAN,KIT,KITLG,MITF,ADAMTS9" Pubmed 15071120 Molecular determinants of synapsin targeting to presynaptic terminals. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "SYN3,SYN1,SYN2,SYP,SYT1" Pubmed 19372219 Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "ADRB2,ARRB1,ARRB2,RACK1,PDE4D" Pubmed 16571605 Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "CALB2,TUBB3,MAP2,RELN,ARX" Pubmed 19185337 Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "CALB2,EPB41,TUBB3,ELP5,TUBA1A" Pubmed 22912413 Slit2 and Robo3 modulate the migration of GnRH-secreting neurons. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "SLIT2,TUBB3,PRPH,ROBO1,ROBO2" Pubmed 23884932 Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "SLIT2,TUBB3,MYO6,ROBO1,ROBO2" Pubmed 17923693 "Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes." Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "CAMK2A,AKAP6,PDE4DIP,SYNPO,SYNPO2" Pubmed 27510895 Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "CALB1,KIAA0319,EDIL3,NEFH,PAX6" Pubmed 25485759 PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Pubmed 7.60E-05 1.00E+00 1.95E-02 2.46E-01 5 8 "NRP2,SLIT2,ROBO1,ROBO2,SEMA3B" Pubmed 19906857 Lhx2 links the intrinsic and extrinsic factors that control optic cup formation. Pubmed 7.70E-05 1.00E+00 1.96E-02 2.48E-01 9 28 "AXIN2,BMP7,LHX2,VAX2,SMAD1,SMAD9,MITF,PAX6,MAPK3" Pubmed 21896628 Secreted frizzled-related proteins are required for Wnt/?-catenin signalling activation in the vertebrate optic cup. Pubmed 7.70E-05 1.00E+00 1.96E-02 2.48E-01 9 28 "AXIN2,BMP7,CALB1,CDH2,SMAD1,SMAD9,PAX6,PARD3,WNT7A" Pubmed 26620267 Impaired Interneuron Development after Foxg1 Disruption. Pubmed 7.70E-05 1.00E+00 1.96E-02 2.48E-01 9 28 "NRP2,CALB1,CALB2,DLX1,EPHB1,GAD1,RELN,ROBO1,SST" Pubmed 19762422 Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins. Pubmed 7.70E-05 1.00E+00 1.96E-02 2.48E-01 9 28 "GPC2,COL9A1,FGFR1,FGFR3,SMAD1,SMAD9,MAPK3,PTCH1,SPP1" Interaction int:TNIK TNIK interactions 1.28E-15 1.69E-11 1.15E-11 1.16E-10 89 282 "AP2A1,AP2A2,BIN1,ANK2,APC,CASK,ZSCAN18,CCAR2,DOCK11,DST,WASF1,CACNA1A,CACNA2D1,CACNB4,KALRN,CAMK2A,CAMK2B,CAMK2G,DGKI,ARHGEF2,CDH2,DCLK1,DLGAP1,TAOK2,NGEF,MAP4K4,HOMER3,NCOR2,SEC24C,SIPA1L1,PDE4DIP,ERC2,ARHGAP32,MATR3,TIAM2,SNAP91,DNM1,SHANK1,DPYSL2,EGFR,MTSS1L,BAIAP2,AGAP2,NOP56,NBEA,NEURL4,DISC1,GLUL,PRRC2B,GRIA2,CIT,GSN,KIF2A,KIF5A,GIT1,MYO5A,NEFM,PCDH8,STRN3,SH3KBP1,PRKACB,PRKAR1B,PRKCB,IQSEC3,KIF7,PPM1E,CNKSR2,SMARCC2,MYCBP2,SPTAN1,IQSEC2,SEPT3,ZC3H4,SYNE2,ARC,AGTPBP1,TRIM2,CLASP1,SYNE1,RIMBP2,CABIN1,TP53BP1,TRIO,TSC1,TUBB2A,HIRA,XPO1,ZIC2,FXR1" Interaction int:DLGAP1 DLGAP1 interactions 1.75E-15 2.31E-11 1.15E-11 1.16E-10 63 167 "TMEM132B,CASKIN1,BEGAIN,APC,CASK,DYNLL1,ADGRB2,ADGRB3,MPDZ,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2G,SEPT7,DLGAP2,DLGAP1,MAP4K4,HOMER3,ARHGAP32,DBN1,SNAP91,DNM1,SHANK1,DPYSL2,RACK1,BAIAP2,AGAP2,NBEA,IQGAP2,GLUL,GRIA2,GRIN2C,GRIN2D,CIT,GSN,SYNPO,LRRTM1,KIF2A,KIF5A,GIT1,ADAM22,MYO5A,NEFH,PDE4B,SH3KBP1,PPP3CA,PRKCB,MAPK3,PTK2,IQSEC3,CNKSR2,SPTAN1,IQSEC2,DDN,ERBIN,MPRIP,SEPT3,ARC,SYNE1,TRIO,KCNAB1,FXR1" Interaction int:DGUOK DGUOK interactions 6.74E-15 8.91E-11 2.97E-11 2.99E-10 37 71 "AMPH,BIN1,ANK2,ATP2B2,CALB2,CAMK2A,CAMK2B,DCLK1,CNTN1,CRMP1,ERC2,SNAP91,DNM1,DPYSL2,DNM1L,EDIL3,NCALD,HPCAL4,GNAO1,GRIA2,L1CAM,LIG4,MAP2,MAPT,GNG2,STX1B,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYN2,SYP,SYT1,VSNL1,DPYSL5" Interaction int:DNAAF2 DNAAF2 interactions 1.01E-14 1.34E-10 3.34E-11 3.36E-10 40 82 "AMPH,ANK2,ATP2B2,CACNA2D1,CALB2,CALM1,CAMK2A,CAMK2B,DCLK1,CNTN1,CRMP1,PLXNA4,SNAP91,DNM1,DPP6,DPYSL2,DNM1L,NCALD,HPCAL4,FAM49B,GNAO1,GRIA2,L1CAM,LSAMP,MAPT,GNG2,STX1B,NAPB,SNAP25,SNCA,STX1A,SEPT3,STXBP1,SYN1,SYN2,SYP,SYT1,VSNL1,NDRG4,DPYSL5" Interaction int:AGAP2 AGAP2 interactions 9.31E-14 1.23E-09 2.46E-10 2.48E-09 66 193 "RALGAPA1,ACTN1,AP2A1,AP2A2,KCTD16,SYNJ1,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2G,SEPT7,DCLK1,DLGAP2,DLGAP1,NUMBL,CLTC,CRMP1,PDE4DIP,APPL1,RIMS2,DBN1,DNM1,DYNC1I1,SHANK1,DPYSL2,EPB41L2,GPHN,PTK2B,AGAP2,NBEA,CAMKK2,IQGAP2,GLUL,GNAO1,PCLO,GRIA2,GRM2,GSN,MAP6,GIT1,MYO5A,NCAM2,NF1,NRCAM,NLGN3,PIK3R1,PPP3CA,PRKACB,PRKCB,MAPK3,MAPK10,PTK2,IQSEC3,PPM1E,CNKSR2,NLGN1,SPTAN1,IQSEC2,MPRIP,STXBP1,SYNE1,SIK3,TP53BP2,TRIO,ANKS1B" Interaction int:HNRNPL HNRNPL interactions 9.82E-13 1.30E-08 1.97E-09 1.98E-08 321 1671 "RALGAPA1,KCNH8,ABR,PLEKHH1,ESYT2,LRFN2,MTA3,ZNF608,INTS2,TBC1D14,SEMA6A,ALCAM,TRMT9B,PITPNM2,OGT,CDC42BPA,APBB2,TNRC6C,SHROOM2,CDC14B,SFMBT2,PPP4R4,CASK,SPTBN4,ARRB1,ARRB2,CDK13,NUMB,EIF4G3,SLC2A11,KIF1A,BARD1,BMPR1B,SYNJ2,FUBP1,BAIAP3,DDR1,PTBP2,CAMK2B,CAST,CBFA2T2,SCARB1,LRBA,ZMYM4,EVI5L,MAGI1,NUMBL,CACNA2D2,SRSF11,FOXN3,EPS15L1,RPL32P3,RAB28,NGEF,FAM19A5,HECTD1,FAM149A,COL4A5,MYRIP,ZNF385A,CDC42BPB,C2CD2,RBM39,SH2B1,ANKRD44,NCOR2,ABCG1,RASGEF1C,PHF14,GREB1,ARHGEF4,DOCK4,DCAF8,HDAC4,TM9SF4,TBC1D5,MATR3,ZC3H11A,SGSM2,USP3,RPS6KL1,SLC12A6,DPP6,DPYSL2,PDCD6IP,DTNA,DTNB,TOM1,SNX29,HIPK3,FAM13A,SUGP2,EGFR,MBNL2,TNK2,PAN3,HSD17B14,VPS13B,EPB41,ERBB2,ETV1,ANKMY1,KATNAL1,ADGRV1,NSRP1,ZNF461,SH3YL1,ZNF589,FECH,FGF13,FGFR3,BAIAP2,PRKAG2,POLK,SCARA3,UBE2E3,SYNCRIP,AGAP3,FOXO3,EVL,SEMA4D,FOLH1,POMT1,ATP2C1,MPP6,ABLIM2,ZMAT1,ZNF44,TMEM8B,SEPT9,SESN1,AHDC1,MALT1,SPIN1,GLI2,GLYR1,TOX3,ZNF638,LUZP2,DCLK2,RAB40B,GNG4,GPT2,PRUNE2,FUT10,GRB10,PARD3B,RNF165,BVES,GUCY1A1,MAN1B1,FRMD3,SYNPO,IGF1,KNDC1,TJAP1,IL6R,ITPKB,JAK2,KLHL23,KCNN2,LSS,PACRG,MAP2,MAP4,MAPT,MARK3,MBNL1,MBP,MKLN1,AFF1,MMP16,MYO5A,MYO6,MYO9A,MYT1,HNRNPM,NCAM2,NFIX,NOVA2,KSR2,NUCB2,OPRL1,GPR137C,ZNF827,PDE4D,PFKFB4,NLGN3,PLEC,PSAT1,EPB41L4B,POLG,PPARA,TATDN3,PPP2R2C,PPP3CA,VSTM2L,PRKACB,PRKAR1B,NDUFS7,BCAS3,VPS13C,WDR25,PTK2,PTPN13,PTPRB,PTPRE,PTPRG,PTPRN2,C1orf109,RIPOR1,MARCH1,ZNF793,HKR1,KHDRBS2,ZDHHC14,TRIM68,SLC25A36,RIC8B,ZNF532,SETD5,KIAA0895L,SGSM1,RPS6KA2,ATAT1,KCNIP3,RXRA,ZNF331,ATXN2,ATXN7,SCP2,FNIP1,TNFRSF19,CASC3,GALNT10,RASA3,PUF60,SCAF8,SH3BGR,SH3BP2,FRMPD1,CHD9,WDR37,NBPF1,KANSL3,PKNOX2,MAST1,RCOR3,TTC17,IFT122,LIMCH1,MBD5,TMCC1,KDM4B,DOP1A,PDZD2,BDP1,FNBP1,NMNAT2,MYCBP2,SPTB,CDK19,TSPYL2,NFASC,LHPP,CLASP2,ZC4H2,LARP4,SSPO,ERBIN,ST5,PHLDB1,ARHGEF9,COBL,ASTN2,ANKRD12,PJA1,CAMTA1,MCF2L,FBXW11,TBL1X,SMG6,MGRN1,ATMIN,TPCN2,PCDHGB1,OBSL1,FRYL,THRA,NACC2,ANKRD24,CSMD1,PARD3,KAT6B,TRIO,TRPM2,TRPS1,TTTY15,HSPBP1,TTC3,UBE2H,SLC35A4,LMF1,ZNF708,ZNF189,DPYSL5,SPIRE1,SMARCAD1,MEIS3,INTS3,SLC30A4,MAP3K12,VPS35L,SEMA3B,WNK2,ST7,KAT6A,HNRNPA3,TMEM63C,JMJD1C,NETO1" Interaction int:SHANK3 SHANK3 interactions 1.04E-12 1.38E-08 1.97E-09 1.98E-08 58 166 "CASKIN1,SPTBN4,HCN2,ARHGEF7,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2G,SEPT7,DCLK1,DLGAP2,DLGAP1,TAOK2,MAP4K4,HOMER3,CNTN1,CDC42BPB,PDE4DIP,ERC2,PPP6R2,DBN1,DCTN1,SNAP91,DNM1,SHANK1,BAIAP2,AGAP2,GLUL,TPPP,GRM2,CIT,SYNPO,MPP2,MYO5A,NF1,NRCAM,PAX6,PPP3CA,PRKCB,MAPK3,RET,KIF7,RPS6KA2,KIF21A,CNKSR2,HECW1,SPTAN1,IQSEC2,NFASC,SEPT3,PLCB1,ANKRD28,SYNE1,TSC1,ANKS1B,FXR1,SPATA13" Interaction int:NUFIP1 NUFIP1 interactions 5.91E-12 7.82E-08 9.77E-09 9.84E-08 45 116 "ADD2,AMPH,BIN1,ANK2,ATP2B2,ATP6V0A1,CALB2,CAMK2A,CAMK2B,CCNT1,DCLK1,CNTN1,CRMP1,SNAP91,DNM1,DPYSL2,DNM1L,EDIL3,NCALD,HPCAL4,FAM49B,GNAO1,GPD2,GRIA2,L1CAM,MAP2,MAPT,SCAMP5,GNG2,STX1B,NAPB,SNAP25,SNCA,STX1A,STXBP1,SYN1,SYP,SYT1,TAF9,TRIM2,VSNL1,XPO1,NDRG4,DPYSL5,CADM2" Interaction int:DLG4 DLG4 interactions 1.73E-11 2.29E-07 2.54E-08 2.56E-07 78 272 "ABR,PCDH10,BEGAIN,LRFN1,KCNAB2,SEMA4G,CASK,DYNLL1,ATP1A1,ATP2B2,ADGRB1,ADGRB3,SYNJ1,KALRN,CAMK2A,CAMK2B,DLGAP2,DLGAP1,ASIC3,CLTC,CNTN1,AKAP5,GDA,SIPA1L1,ARHGAP32,DBN1,GRIN3A,SHANK1,DPYSL2,ERBB2,ERBB4,PTK2B,BAIAP2,AGAP2,NBEA,FYN,IQGAP2,GLUL,GNAO1,GRIA2,GRIK5,GRIN2C,GRIN2D,CIT,ZDHHC15,TJAP1,KCND2,KCNJ16,KIF2A,KIF5A,MPP2,GIT1,ADAM22,NEFH,NRCAM,NTRK2,NLGN3,PIK3C2A,SH3KBP1,PPP3CA,PRKACB,PRKCB,PTK2,PTPRG,MAPK12,CNKSR2,NLGN1,FAM81A,IQSEC2,ERBIN,SYNE2,ARC,SYT1,SYNE1,TSC1,ANKS1B,KCNAB1,NETO1" Interaction int:SYNGAP1 SYNGAP1 interactions 2.72E-11 3.60E-07 3.60E-08 3.62E-07 50 142 "BEGAIN,PITPNM2,AMPH,KCNAB2,ADGRB2,MPDZ,SYNJ1,KALRN,CAMK2A,CAMK2B,DLGAP2,DLGAP1,CNRIP1,GDA,ARHGAP32,DBN1,DNM1,SHANK1,DPYSL2,DNM1L,EPB41L2,PTK2B,BAIAP2,AGAP2,NBEA,IQGAP2,GLUL,GNAO1,LNX1,GRIA2,GRIN2D,SHISA6,ITPKA,GIT1,ADAM22,MYO5A,NTRK3,OPA1,PLCL1,MAPK3,CNKSR2,FAM81A,MYCBP2,IQSEC2,DDN,SYN1,ARC,DMXL2,TSC1,ANKS1B" Interaction int:CYFIP1 CYFIP1 interactions 2.96E-09 3.92E-05 3.56E-06 3.58E-05 53 174 "AP2A1,HECW2,GAS7,MARK4,WASF1,CAMK2A,CAMK2B,ARHGEF1,ARHGEF2,DCLK1,DLGAP1,NUMBL,SLC4A8,PREPL,CRMP1,ERC2,MATR3,DBN1,DCTN1,SNAP91,DNM1,NYAP1,SHANK1,DPYSL2,PDCD6IP,DNM1L,BAIAP2,AGAP2,TCERG1,GLUL,LNX1,NCKAP1L,SYNPO,TMEM240,KCNB1,KIF2A,MYO5A,NEFH,NTRK2,OPA1,P2RX7,PDE4A,PIK3R1,PRKCB,RTN1,SBF1,ARX,MYO16,SPTAN1,LRRC24,TSC1,AMZ1,FXR1" Interaction int:DISC1 DISC1 interactions 3.39E-08 4.49E-04 3.63E-05 3.66E-04 43 137 "SPARCL1,CEP126,GPRASP2,PPFIA4,SPTBN4,DST,KALRN,AKAP6,MATR3,DCTN1,TIAM2,DMD,DYNC1I1,DPYSL2,ASB3,KATNAL1,OLFM1,DCTN2,SMC2,DISC1,CIT,MGAT3,NEFM,PDE4B,KANSL1,PPP5C,ANKHD1,ROGDI,FBXW7,PPM1E,SYBU,CDK5RAP3,CCDC88A,ATF7IP,SPTAN1,EXOC7,AGTPBP1,SYNE1,FRYL,TRIO,TUBB2A,CCDC136,TFIP11" Interaction int:YWHAZ YWHAZ interactions 3.57E-08 4.72E-04 3.63E-05 3.66E-04 122 567 "KCTD16,CEP126,KCNAB2,PPFIA3,MADD,ARRB1,MARK4,ATP2B2,BARD1,KSR1,ARHGEF7,CAMK2A,CAMK2B,CAMK2G,ARHGEF2,CDC25B,DLGAP1,CLTC,FAM189A2,HOMER3,ARHGEF6,NSL1,NCOR1,HDAC9,RIPOR2,HDAC4,RASSF2,MATR3,PARD6A,DNM1L,OPTN,APH1A,EGFR,EIF5,EPB41L2,PRMT5,KAT8,MEX3B,FOXO3,EVL,GABBR1,DISC1,FERMT2,LNX1,GP1BB,GSN,PADI2,GABARAPL2,SYNPO,IDH3B,ITPKA,KCNK3,KIF2A,MAP2,MAP6,MAPT,MARK1,MARK3,MBP,MEF2C,MOV10,GIT1,ADAM22,MYO5A,NF1,PDE1B,PFKFB2,OLA1,PLEC,PPP3CA,PPP3CC,PRKACB,MAPK7,PTPN13,PTPRO,ROGDI,RASGRF2,RGS3,LRRK2,SBF1,TRA2B,SGK1,MYO18A,SHMT2,CNKSR2,WDR37,CCDC88A,MAST1,BDP1,UHRF1BP1L,MYCBP2,ERC1,SPTAN1,RBM26,ITPRID2,SAMSN1,STAU1,KLHL7,SYN1,SYN2,FBXW11,DMXL2,KIAA0930,RPGRIP1L,OBSL1,SIK3,PARD3,TNS1,TP53BP1,TP53BP2,SYNPO2,TSC1,TSC2,TUBB2A,UBE3A,CLIP2,KLC2,XPO1,REEP1,TUBA1A,WNK2,SPATA13" Interaction int:ATXN1 ATXN1 interactions 5.13E-08 6.78E-04 4.84E-05 4.87E-04 67 260 "ADCY6,KCNAB2,SEMA4G,ATP1A3,CAMK2B,ENTPD6,NUMBL,PLEKHB1,QKI,CREM,CRY2,NCOR1,NCOR2,CST3,DZIP3,PUM1,PPP6R2,ARHGAP32,HDAC4,TBC1D5,IST1,ZNF804A,MYEF2,POM121,DMPK,HEYL,SUGP2,UBE2E3,FYN,AHDC1,ZNF276,PRRC2B,CLASRP,ZHX1,ATXN2L,ACOT7,MATN2,MBP,KCTD15,VSTM2L,QRICH1,ANKHD1,FAT4,YY1AP1,BAALC,ST6GALNAC6,ATXN2,SUPT20H,MYO18A,R3HDM2,SYBU,SMARCC2,ZHX3,ZSWIM8,UHRF1BP1L,RBM26,STAC2,MLST8,R3HDM1,IL34,ELP5,TSC1,EIF4ENIF1,CCDC136,VSNL1,WNK2,KAT6A" Interaction int:HAX1 HAX1 interactions 6.46E-08 8.54E-04 5.69E-05 5.73E-04 42 135 "AMPH,ANK2,CALB2,CAMK2A,CAMK2B,DCLK1,CNTN1,CRMP1,SNAP91,DNM1,DPP6,DPYSL2,DNM1L,EDIL3,TNK2,NCALD,IQGAP2,GNAO1,GPD2,GRIA2,HNF4G,L1CAM,MAP2,MAPT,GNG2,ABCB1,PPP3CC,MAPK10,STX1B,NAPB,SNCA,STX1A,STXBP1,SYN1,SYN2,SYP,SYT1,CDK20,VSNL1,XPO1,NDRG4,DPYSL5" Interaction int:ARMC1 ARMC1 interactions 2.10E-07 2.78E-03 1.48E-04 1.49E-03 20 44 "CALM1,CAMK2A,CAMK2B,CNTN1,CRMP1,DPYSL2,NCALD,DCTN2,GNAO1,MAP2,MAPT,GNG2,STX1B,STXBP1,SYN1,SYN2,SYT1,HSPBP1,VSNL1,DPYSL5" Interaction int:FMR1 FMR1 interactions 2.10E-07 2.78E-03 1.48E-04 1.49E-03 69 280 "CASKIN1,BIN1,LRCH2,PKP4,APC,CCAR2,DYNLL1,CACNB4,CAMK2A,CAMK2B,CAMK2G,LDB2,ARHGEF2,MAGI1,DLGAP1,NUMBL,MAP4K4,HOMER3,CNTN1,MAGED1,NCOR1,NCOR2,ARHGAP24,MATR3,DAPK3,PLPPR4,DNM1,DPYSL2,EIF4G1,APC2,AGAP2,RGPD5,NBEA,BRSK1,PRRC2B,IFI16,KIF2A,KIF5A,GIT1,PRKCB,PTPRN2,PBRM1,FBXW7,ATXN2,CASC3,TRA2B,WDR47,SMARCA4,SMARCC2,CDK5RAP2,SNCA,UHRF1BP1L,MYCBP2,IQSEC2,STAU1,PRRC2C,MTCL1,TBL1X,SMG6,SIN3B,CLASP1,SIK3,ICAM5,PARD3,TNS1,TP53BP1,TSC1,EMSY,FXR1" Interaction int:FXR1 FXR1 interactions 2.12E-07 2.80E-03 1.48E-04 1.49E-03 57 216 "AP2A1,AP2A2,CEP126,MYH7B,PPFIA3,CCAR2,DYNLL1,ARHGEF7,CAMK2A,CAMK2B,ARHGEF2,CDH2,DLGAP1,LRWD1,EPS15L1,MAP4K4,CRMP1,NCOR1,NCOR2,SEC24C,PDE4DIP,GPRASP1,GIT2,MYEF2,SEC16A,EXOG,FARSB,BAIAP2,RGPD5,ANKFY1,NOP56,PRRC2B,DIDO1,IFI16,KIF2A,AFDN,GIT1,HNRNPM,CDK18,RDX,KIF7,CLIP1,SBF1,KIF21A,WDR47,CCDC88A,SMARCA4,SMARCC2,SNCA,MYCBP2,PRRC2C,DNAJC9,TP53BP1,TSC1,TTC3,FXR1,SPATA13" Interaction int:PDE4DIP PDE4DIP interactions 2.13E-07 2.81E-03 1.48E-04 1.49E-03 71 291 "CASKIN1,AMPD2,CCDC146,PKP4,PPFIA3,DYNLL1,WASF1,KALRN,CAMK2A,CAMK2B,CDH2,LRRFIP1,MAP4K4,HOMER3,ARMC8,RGS6,CSNK1E,OSBPL3,PDE4DIP,DZIP3,ERC2,ARHGAP32,HDAC4,MATR3,ARMCX4,JAKMIP2,SHANK1,DPYSL2,FRY,FHL1,AGAP2,NBEA,GATM,CIT,KIF2A,GIT1,CCDC13,NF1,KSR2,PDE4D,ZFYVE21,JAKMIP1,PRKACB,PRKCB,PTPRN2,C1orf109,RDX,KIF7,CLIP1,WDR47,CCDC88A,ATF7IP,CDK5RAP2,SNCA,SPTAN1,CLASP2,KLHL7,SYNE2,ANKRD28,ZEB1,CLASP1,PARD3,TP53BP1,TP53BP2,VGF,CLIP2,ZBTB38,ZSCAN26,TFIP11,STOX2,FXR1" Interaction int:CYFIP2 CYFIP2 interactions 3.61E-07 4.77E-03 2.38E-04 2.40E-03 31 91 "AP2A1,CASKIN1,GAS7,MARK4,WASF1,CAMK2A,CAMK2B,CDH2,DLGAP1,HOMER3,APPL1,DNM1,NYAP1,SHANK1,BAIAP2,AGAP2,TCERG1,PACSIN2,NCKAP1L,MYO5A,NLGN3,PTPRE,MYO16,MYCBP2,SPTAN1,STAU1,DNMBP,TCF4,TSC1,AMZ1,FXR1" Interaction int:YWHAH YWHAH interactions 1.27E-06 1.67E-02 7.60E-04 7.65E-03 59 238 "CC2D2A,ARRB1,ARRB2,MARK4,NCOA1,ALDH7A1,ARHGEF2,CDC25B,DLGAP1,CHRNA4,HOMER3,SNCAIP,RIMS2,HDAC4,RASSF2,RUSC2,PARD6A,WDR20,OPTN,EIF5,EPB41L2,MEX3B,FOXO3,FERMT2,CNTRL,RASSF8,FRMD5,KCNH2,KCNK3,MAPT,MARK1,MARK3,PTOV1,NEK1,NF1,PDPK1,MAPK7,PTH1R,ZC3H14,LRRK2,FAM192A,CCDC88A,MAST1,SNCA,MYCBP2,SAMSN1,KIAA0930,RPGRIP1L,TNS2,FRYL,SIK3,THRA,PARD3,TP53BP2,TSC1,TSC2,XPO1,FRMD6,SPATA13" Interaction int:RAC1 RAC1 interactions 1.27E-06 1.67E-02 7.60E-04 7.65E-03 59 238 "ABR,HACE1,LTBP4,ARHGDIA,ARHGDIG,SYNJ2,ARHGEF7,WASF1,CALM1,KALRN,ARHGEF25,USP6,ARHGEF2,ARHGAP33,MAGI1,DLGAP1,CHN1,CHN2,ARHGAP22,MYL6B,CLTC,ARHGEF6,ARHGEF4,CYBB,ARHGAP32,BRINP1,PARD6A,DMPK,DOCK2,TOM1,BAIAP2,AGAP2,IQGAP2,CIT,KTN1,GIT1,NCF2,OCRL,PIK3R1,PKM,PLXNB1,PSAT1,PPP2R2B,PTK2,RAP1GDS1,RASGRF1,LRRK2,CLIP1,SH3BP2,IQSEC2,STAU1,MCF2L,TIAM1,TRIO,TSC1,VAV1,HPS4,DOCK8,UBE3B" Interaction int:ITSN2 ITSN2 interactions 1.59E-06 2.10E-02 9.12E-04 9.18E-03 30 92 "AGT,SEMA6A,LTBP4,AMPH,MAP4K3,DST,SYNJ2,DLGAP1,EPS15L1,PDE4DIP,TM9SF4,PDCD6IP,GOLT1B,EGFR,MEGF10,AHDC1,GAREM2,ITPKA,PIK3AP1,MBNL1,SH3KBP1,PTN,PPP4R3A,ERC1,SYN1,TACC1,NR2C2,TRIO,UBC,WIPF1" Interaction int:GRIN2B GRIN2B interactions 1.74E-06 2.30E-02 9.42E-04 9.48E-03 31 97 "AP1M1,KALRN,CAMK2A,CAMK2B,CAMK2G,AP4M1,CDH2,DLGAP1,CLTC,AKAP5,ARHGAP32,GRIN3A,DNM1,PTK2B,RACK1,AGAP2,FYN,CIT,MAP2,SHC3,NF1,PIK3R1,PPP3CA,PPP5C,PRKCB,MAPK3,SPTAN1,ERBIN,ARC,EXOC7,TUBA1A" Interaction int:KALRN KALRN interactions 1.78E-06 2.35E-02 9.42E-04 9.48E-03 25 70 "PKP4,CACNA1A,KALRN,CAMK2A,CAMK2B,CAMK2G,DLGAP1,SNCAIP,SIPA1L1,PDE4DIP,AGAP2,DISC1,LNX1,GRIA2,CIT,SYNPO,GIT1,ADAM22,MYO5A,ATXN7,CNKSR2,SPTAN1,IQSEC2,DICER1,TRIO" Interaction int:GNB1 GNB1 interactions 2.62E-06 3.46E-02 1.33E-03 1.34E-02 34 113 "ADRB2,ARRB1,BTK,CACNA1A,CACNA1B,KALRN,DLGAP1,COX4I1,RGS6,HDAC4,DYNC1I1,DUSP9,APH1A,RACK1,AGAP2,FYN,DISC1,GNAO1,GNG4,SYNPO,NCF2,GNG2,PIK3R1,PTH1R,PTK2,RIC8B,CNKSR2,RADIL,MCF2L,PIK3R5,RASD2,UBC,RICTOR,XPO1" Interaction int:PCDHGB1 PCDHGB1 interactions 3.22E-06 4.25E-02 1.58E-03 1.59E-02 25 72 "PCDH19,PCDH10,LRFN1,PCDHGB4,ATP2B2,NRP2,CNTN1,C2CD2L,CDON,CELSR3,SPECC1,GPD2,STMN2,PCDHGC3,PCDH9,PCDH18,SDK2,FAT4,NEK4,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA9,PCDHA1,PCDH20" Interaction int:USP21 USP21 interactions 4.16E-06 5.50E-02 1.97E-03 1.98E-02 38 135 "HECW2,LRFN1,MARK4,RIPK1,KSR1,IL33,USP2,ARHGEF2,CDC25B,DCLK1,MAGI1,SIPA1L1,HDAC4,KCTD3,STAMBP,USP21,GLI2,ZNF638,USP51,MAP4,MARK1,MARK3,SRSF12,KCTD6,AFDN,NF1,TBC1D25,MAPKAP1,EXOSC10,MAPK3,WDR47,USP33,ANKRD28,SYNE1,TIAM1,UCHL1,XPO1,TRIM9" Interaction int:AP2A1 AP2A1 interactions 6.20E-06 8.19E-02 2.83E-03 2.84E-02 36 127 "AP2A1,AP2A2,AMPH,BIN1,ARRB1,ARRB2,NUMB,SYNJ1,CLTB,CLTC,PPP6R2,DBN1,SEC16A,DPYSL2,EGFR,AGAP2,SYT3,STAMBP,GHR,RUNDC3A,LNX1,SYNPO,L1CAM,SMAD9,MYO6,OCRL,FBXW7,ARX,MYO18A,ARFGAP1,SNAP25,MMS19,OBSL1,UBC,XPO1,FXR1" Interaction int:GRIN1 GRIN1 interactions 1.11E-05 1.47E-01 4.79E-03 4.82E-02 32 110 "NUMB,CALM1,CAMK2A,CAMK2B,CAMK2G,CDH2,DLGAP1,CLTC,AKAP5,APPL1,GRIN3A,DNM1,PTK2B,AGAP2,FYN,LNX1,GRIN2D,CIT,MAP2,SHC3,NF1,PIK3R1,PPP3CA,PPP5C,PRKCB,MAPK3,SPTAN1,ARC,TIAM1,TP53BP1,KLC2,TUBA1A" Interaction int:YWHAE YWHAE interactions 1.12E-05 1.48E-01 4.79E-03 4.82E-02 108 544 "SYN3,OGT,LRCH2,SHROOM2,ARRB1,ARRB2,MARK4,ALDH7A1,KSR1,CALM1,CBR1,ARHGEF2,CDC25B,DCLK1,ARHGAP33,DLGAP1,CLTC,FAM189A2,HOMER3,RCHY1,CRY2,NCOR2,OSBPL3,ERC2,RIMS2,RUBCN,HDAC9,HDAC4,RASSF2,GIT2,DBN1,DNM1L,APH1A,EIF5,DENND4A,KAT8,FGF12,BAIAP2,MEX3B,FOXO3,MSANTD4,BRSK1,DISC1,SPIN1,DCLK2,FERMT2,GRB10,RASSF8,KCNH2,KCNK3,KIF5A,MAPT,MARK1,MARK3,AFDN,GIT1,DBNL,NF1,CDK18,PFKFB2,PPM1B,MAPK7,PRPSAP2,RAP1GDS1,RASGRF1,RGS3,LRRK2,ATAT1,TRA2B,SHMT2,R3HDM2,WDR37,SLC8A1,CCDC88A,MAST1,SNCA,ERC1,CLASP2,ITPRID2,SAMSN1,MPRIP,SYN1,SYN2,FBXW11,KIAA0930,RPGRIP1L,CLASP1,OBSL1,TNS2,CRTC1,SIK3,TIAM1,ACTR6,TMPO,PARD3,TP53BP2,TSC1,TSC2,TUBB2A,UBE3A,KLC2,XPO1,REEP1,POLR3H,TUBA1A,DOCK8,HNRNPA3,SPATA13" Interaction int:RGS4 RGS4 interactions 3.10E-05 4.09E-01 1.28E-02 1.29E-01 9 15 "CALM1,KRIT1,COPB2,PREPL,EGFR,GABBR1,GNAO1,RGS4,PLCB1" Interaction int:PEX5L PEX5L interactions 3.43E-05 4.53E-01 1.36E-02 1.37E-01 17 45 "ADD1,AP2A1,AP2A2,CASKIN1,KCTD16,SLC4A4,HCN2,CAMK2A,ARHGEF2,CDH2,DBN1,GIT1,MYO5A,SPTAN1,ICAM5,PARD3,PPP1R3F" Interaction int:PPFIA4 PPFIA4 interactions 3.50E-05 4.63E-01 1.36E-02 1.37E-01 6 7 "PPFIA4,CAST,ERC2,DISC1,GIT1,AGTPBP1" Interaction int:DNM1 DNM1 interactions 3.65E-05 4.82E-01 1.38E-02 1.39E-01 28 96 "AP2A2,CEP126,AMPH,BIN1,ARRB1,DLGAP1,CLTC,DNM1,PTK2B,RACK1,FER,AGAP2,GRIN2D,PACSIN2,KIF2A,KIF5A,PIK3R1,SH3KBP1,RPE,SCN2B,SH3GL3,SNAP25,FNBP1,DNMBP,CABIN1,TBC1D15,LYPD6,TUBA1A" Interaction int:CAMK2N2 CAMK2N2 interactions 4.99E-05 6.59E-01 1.83E-02 1.84E-01 5 5 "CAMK2A,CAMK2B,ARHGAP32,LNX1,CAMK2N2" Cytoband 5q31 5q31 1.19E-15 1.19E-12 1.19E-12 8.93E-12 38 115 "NME5,PCDHGB4,ALDH7A1,KLHL3,CDKL3,REEP2,FGF1,BRD8,TCERG1,PCDHGC3,PCDHB17P,ARHGAP26,SEPT8,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Transcription Factor Binding Site CTGCAGY_UNKNOWN CTGCAGY_UNKNOWN 1.90E-12 1.16E-09 6.28E-10 4.39E-09 154 607 "AXIN2,ADORA2A,AP2A1,MTUS1,KLHL13,C1QTNF3,SEMA6A,ALCAM,ABCD2,DOC2A,PHF12,APBB2,CASK,ATP1A3,STX16,ADGRB2,ADGRB3,CALM1,CAMK2G,SPAG9,CBLN1,CDH2,DCLK1,DLGAP1,CFL2,FOXN3,NRXN3,COL11A2,MAGED1,TBPL1,BAG4,ABCG1,PHACTR3,SLITRK5,HDAC9,SNPH,SPOCK2,GIT2,ELMO1,GRIN3A,DMD,DNM1,CD99L2,DMTF1,DPYSL2,DUSP9,CNNM1,MBNL2,EGR3,EIF4G2,DCTN4,ENO2,EPB41,GPHN,APC2,ETV1,RRAGB,DLC1,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FHL1,MEX3B,IP6K2,FOXO3,SYT3,NBEA,USP21,ATP2C1,CELF1,TPPP3,FYN,GABRA3,KIAA1841,PCDH17,GGT7,RAB30,STMN2,GRIN2D,MYLK2,NKD1,LRRTM1,ITGA7,KCND1,KCNH2,KCNN2,KCNN3,MAP4,MAPT,ADAM11,LRP1B,MEIS1,KITLG,AMZ2P1,NBL1,NFIX,NNAT,NOVA1,NTRK2,PAX6,PCDH9,PDE4D,NLGN3,SEMA5B,PIK3R1,PLXNB1,PNMA3,EPB41L4B,PPP2R2B,MAPK7,PSD,PTK2,PTX3,RAD51D,PRIMA1,ZNF532,FBXW7,KCNIP1,SALL1,SARS,SATB1,LRFN5,SCN8A,MYO18A,ATF7IP,SMARCD3,SNRPN,ZSWIM8,LMO3,POGZ,TTBK2,RGL1,ANKRD28,SZT2,PCDHB15,PCDHB4,NSD1,PUM2,CHST8,HEY1,TIMP4,TRPS1,RUSC1,HIRA,VSNL1,XPO1,FSTL5,GAL3ST3,KCNAB1,RTN4,JMJD1C" Transcription Factor Binding Site CTTTGT_V$LEF1_Q2 CTTTGT_V$LEF1_Q2 2.05E-12 1.26E-09 6.28E-10 4.39E-09 323 1547 "KCNH8,NCKAP5,NDRG2,AXIN2,ADORA1,ADRB2,MTUS1,OSBPL6,C1QTNF1,SEMA6A,SPOP,SRPX,BBOX1,OGT,LRCH2,ANK2,SEMA7A,PHF12,GAS7,SEMA4G,CASK,TMEFF1,ARRB2,NUMB,RASL11B,ATP1A3,ATP1B3,ZNF583,ATP6V0A1,BACH1,BCHE,RGS9,NRP2,BMPR1B,ARHGEF7,CACNA1G,WASF1,DDR1,CACNA2D1,PTBP2,SPAG9,CBLN1,LDB2,CCNT1,RGN,AP4M1,ARHGEF2,CDH2,CDO1,CRLF1,NUMBL,CFL2,FOXN3,CHN2,EPS15L1,RAB33A,HECTD1,MAP4K4,CNN3,CNR1,CNTFR,AKAP7,PCYT1B,COL9A1,TBPL1,ZNF521,IGDCC3,ZNF385A,AKAP12,CRMP1,HAPLN1,CS,CSNK1E,SOCS5,RIMS4,PHACTR3,SLITRK5,PPP1R16B,ARHGEF4,PYGO1,DOCK4,ARHGAP24,RASSF2,DGKB,DAPK1,PITPNC1,ARMCX2,RHOBTB1,CHRDL1,DLX1,DMD,NYAP1,USP3,CD99L2,CDON,DPYSL2,ECM2,ABCC5,PHC2,KLHL5,MBNL2,EGR3,PLXNC1,EIF4G1,EIF4G2,ING4,LRRC17,APC2,ETV1,PIPOX,TLR7,RRAGB,EXTL2,KATNAL1,EYA1,HSPA12B,CLVS1,TBC1D16,SCML2,FECH,FGFR3,FHL1,UBE2E3,MEX3B,FOXF2,IP6K2,SYNCRIP,FOXO3,ATP2C1,CELF1,NSG1,DLL3,AP4B1,OGA,FYN,MEGF10,CHL1,GABRG2,GAD1,KIAA1841,GCNT2,GDF1,MSTN,PCDH17,PPARGC1A,LYVE1,BRD8,RAB30,STARD3,LOXL3,GPR12,STMN2,GRIN2D,GRM2,ZNF496,BTN2A1,PTPRT,GSN,KAT7,SLC2A6,MAP4K5,ATOH8,BACH2,HSF2,NKD1,ZIC5,RBPJ,INSM1,LRRTM1,KCND2,KIF5A,KIT,KTN1,L1CAM,STMN1,SMAD1,MAP2,MAPT,MAT2A,SHC3,MEF2C,MEIS1,MEIS2,KCTD6,MID1,MITF,AFDN,MMP16,MN1,MPP2,GIT1,PTOV1,MXI1,MYT1,HNRNPM,NBL1,NDP,NFIX,NFYA,NNAT,CNOT4,NRCAM,IGSF11,P2RX7,ZNF827,PALM,PAX6,PCDH9,PCSK1,PDE4D,GPR85,TMOD2,PFKFB3,SERPINI1,SEMA5B,PIK3R1,CCSER2,KCTD15,PLEC,SMOX,PCDH18,PDZRN4,PPP2R2B,RASGEF1B,CEP41,PKIA,MASP1,PSD,GDPD2,PTH1R,PTPRG,PTPRO,ZCWPW1,RBBP6,ZDHHC14,DUSP15,DPF2,RFX3,RGS3,PBRM1,ZNF532,ROBO1,KIRREL1,RORB,RTN1,RYR3,FAM192A,SEMA6D,SATB1,HES6,SMPD3,SH3BGR,KIF21A,ARX,FBXO11,CNKSR2,PREX2,BTBD3,DHX30,FAM214B,KANSL3,LGI3,EPC1,CXXC4,SMARCA4,SMARCC2,SOX11,KDM3A,SP4,LMO3,THSD1,NKAIN2,SS18,ERBIN,ST5,MPRIP,SEPT3,KLHL7,ASTN2,ANKRD12,MCF2L,TAL1,ADGRL3,FBXW11,KLHL4,TCF12,CLASP1,PCDHGA11,NSD1,PCDHAC2,ZFPM2,GPR161,GALNT17,TIAM1,HEY1,NR2E1,TPM1,STXBP4,CA14,TSC1,HIRA,UBE2H,UBTF,UCHL1,P2RY12,WNT7A,ZIC1,ZNF32,MKRN3,FSTL5,ZNF184,DPYSL5,SMARCAD1,PRTFDC1,SLC38A1,ADAMTS9,NAV3,PCBP4,FAM13C,ST7,RTN4,KAT6A,JMJD1C" Transcription Factor Binding Site TGACATY_UNKNOWN TGACATY_UNKNOWN 5.23E-08 3.20E-05 1.07E-05 7.47E-05 125 534 "ABR,ADCY6,ADRA1B,SLC24A4,AP2A2,SYT13,APBB2,GAS7,MADD,CDK13,ASGR1,DOCK11,ADGRB2,BCHE,NRP2,CACNA1G,C5,CA12,DDR1,CABP7,CALM1,CBFA2T2,LARGE1,CFL2,FOXN3,CLTB,HECTD1,CNN3,ARHGEF6,COL4A5,AKAP5,RTTN,ZNF521,NECTIN3,CREM,AKAP12,HAPLN1,RNF14,SNCAIP,RGS6,SLITRK5,ARHGAP24,KIAA0586,DAPK3,SPOCK2,PITPNC1,ELMO1,DMD,CELSR3,EGFR,TENM1,RCAN2,EYA1,PPP1R1B,OLFM1,FGF12,FGFR3,SYNCRIP,AKAP3,FYN,GABRG1,RAPGEF6,MSTN,RAB30,ELOVL5,IGF1,INSM1,KCNH2,KCNN2,LIFR,LIMS1,MAP2,MBNL1,ADAM11,LRP1B,MEF2C,MEIS1,MEIS2,MID1,MITF,MYO7A,MYT1,NOVA2,PDE1C,PDE4D,ENPP2,GPR85,PIK3R1,CCSER2,FXYD1,PDZRN4,SCHIP1,MAPK10,PTPRD,RAP1GDS1,RBBP6,DPF2,RORB,SBF1,LRFN5,SCN7A,SCN8A,TNFRSF19,SMPD3,RASA3,SH3BGR,TTC17,FAIM2,LMO3,SS18,ST5,TTBK2,STAC2,SYNE2,FBXW11,TBL1X,DNAH7,DICER1,ZIC1,TRIM9,FSTL5,KCNAB1,FBXO36,SNX14,DPF3" Transcription Factor Binding Site TTGTTT_V$FOXO4_01 TTGTTT_V$FOXO4_01 2.64E-07 1.61E-04 4.03E-05 2.82E-04 306 1603 "CLK4,AXIN2,ADORA1,KLHL13,C1QTNF3,SPARCL1,SEMA6A,ARHGAP20,BIN1,OGT,LRCH2,APBA2,APC,CDC14B,SEMA4G,PRX,TMEFF1,RGS20,ARRB2,LINC00173,STK33,ASPA,SLC4A4,STX16,ATP2A2,ATP6V0A1,DOCK11,RGS9,BCL7A,NRP2,BLM,WASF1,CACNA2D1,CALB1,CABP7,HIP1R,SPAG9,NFS1,CBLN1,KYAT1,LDB2,USP2,CBFA2T2,CD38,AP4M1,CRLF1,CACNA2D2,CFL2,FOXN3,CHN1,CHN2,RAB33A,QKI,MAP4K4,FHL5,ARHGEF6,CNR1,PCYT1B,COL4A5,COL9A1,ZNF521,CPS1,CREM,CRMP1,HAPLN1,CRY2,SNCAIP,CSNK1G3,SIPA1L1,SLITRK5,KIAA0040,GREB1,PUM1,DOCK4,HDAC9,RASSF2,KIAA0586,MAML1,IP6K1,BRINP1,PITPNC1,KLHL3,CHRDL1,DLX1,DMD,USP3,SLC12A6,ECM2,ABCC5,MBNL2,EIF4G1,ING4,EMX2,LRRC17,ENPP6,ERBB4,NCALD,ETV1,EYA1,EZH1,CLVS1,ACSL4,DLC1,SEC24B,OLFM1,FGF12,FGF13,FGF14,PRKAG2,IP6K2,EVL,FLT1,AKAP3,TPPP3,MPP6,CHL1,GABRG1,GABRG2,KIAA1841,ARFIP1,ADAM28,PCDH17,GHR,PPARGC1A,RUNDC3A,BRD8,RAB30,MSL3,GNAO1,GPR12,STMN2,GRIK4,KAT7,SOX21,MAP4K5,ATOH8,HAS2,NXPH3,GABARAPL2,AGBL5,HNF4G,ZDHHC15,IGF1,NKD1,ZIC5,NIM1K,IL6ST,INPP1,LRRTM1,KCNJ16,KCNN1,KCNN2,STMN1,HECTD2,SMAD1,MARK1,MARK3,MAT2A,AQP11,MEF2C,MEIS1,MEIS2,KCTD6,KITLG,PPM1L,MITF,GIT1,MSI1,PTOV1,HS6ST3,MXI1,NBL1,NDP,NEK1,NF1,NFE2L2,NFIX,NOVA1,NPTX1,NPTX2,NTRK2,NTRK3,PALM,PAX6,PCDH8,PDCD2,PDE4D,ENPP2,PFKFB3,ABCB1,SEMA5B,PIK3C2A,PIK3R1,PLCB2,FXYD1,PCDH18,PDZRN4,SDK2,PPM1B,PPP2R2B,LRRN3,RASGEF1B,CEP41,PKIA,MAPK3,MAPK10,MASP1,APTX,PTN,PTPRD,ZCWPW1,ZDHHC14,GTDC1,FIGN,ZDHHC4,RGS3,NUDT11,ZNF532,ROBO1,KIRREL1,RORB,NEK11,RTN1,SEMA6D,SATB1,LRFN5,TNFRSF19,SMPD3,COPZ1,SGK1,FRMPD1,CPEB3,MYO18A,FBXO11,ABLIM3,PREX2,BTBD3,EPN2,DHX30,PKNOX2,SEPHS1,ATF7IP,CPEB4,CXXC4,SMARCA4,TTC17,MBD5,FAIM2,TRERF1,SOX3,FNBP1,KDM3A,SP4,NMNAT2,LMO3,CLSTN2,SST,ERBIN,ST5,ELOVL4,APOM,TTBK2,KANK1,SULF2,NUDT10,ANKRD28,TAL1,ADGRL3,TCF4,SATB2,DOCK9,NSD1,SIK3,TEK,DNAH7,DICER1,ZFPM2,CHST8,THRA,TIAM1,HEY1,WBP2,NR2C2,TRPS1,CA14,TSC1,SSBP2,UBE2H,UBE3A,UGT8,TOM1L2,VLDLR,XRCC4,ZIC1,ZIC2,ZNF24,FSTL5,DPYSL5,PRDM8,NAV3,FIP1L1,EPM2A,PHTF2,JMJD1C,FXR1,JPH3" Transcription Factor Binding Site RTAAACA_V$FREAC2_01 RTAAACA_V$FREAC2_01 5.58E-07 3.42E-04 6.84E-05 4.78E-04 159 746 "NDRG2,AXIN2,C1QTNF3,UNC79,BIN1,DPP10,ANK2,SEMA4G,ARNTL,CADPS,LINC00173,ASPA,ZBTB10,STX16,ADGRB3,CASTOR3,CBFA2T2,AP4M1,ARHGEF2,CLGN,CFL2,FOXN3,PPT2,NGEF,ARHGEF6,PCYT1B,ZNF521,SNCAIP,CSNK1G3,PHACTR3,SLITRK5,CTH,SCRN1,SPOCK2,PITPNC1,ELMO1,DLX1,DMD,NYAP1,USP3,SLC12A6,RCAN1,EDN1,MBNL2,TENM1,EMX2,ERBB2,ERBB4,ETV1,EYA1,MRVI1,EZH1,DLC1,FGF12,FGF14,MEX3B,IP6K2,FOXO3,MPP6,OGA,FYN,SDCBP2,RAPGEF6,GCNT2,PPARGC1A,BRD8,GLYR1,RAB30,GNAO1,ADAMTS13,MAP4K5,BACH2,GABARAPL2,SYNPO,HSF2,IGF1,NIM1K,IL6ST,KCNH2,KCNN3,LIFR,SMAD1,SMAD9,MATN2,MBNL1,MEIS1,MID1,MITF,MMP16,MN1,MYT1,NF1,NFIX,NFYA,NINJ2,NTRK3,P2RX7,PALM,PCDH9,PCSK1,PCSK5,ENPP2,ABCB1,NLGN3,PIK3C2A,RETREG1,KCTD15,PLCB2,SMOX,PCDH18,PDZRN4,ING3,PPP2R2B,PPP3CA,RASGEF1B,PKIA,MAPK3,MAPK10,BCAS3,PTH1R,ZNF532,ROBO1,RORB,FBXW7,SEMA6D,TNFRSF19,SCAF8,KIF21A,ARX,CPEB3,ABLIM3,PREX2,BTBD3,ABTB1,SNAP25,TRERF1,ZNF423,LMO3,ANKRD28,PJA1,TCF4,SATB2,TRIM2,TCF12,TNS2,TEK,THRA,TIAM1,TRPS1,TSC1,UBE2H,BCL2L13,KLC2,NPDC1,TRIM9,MKRN3,SH3GLB2,FAM13C,KAT6A" Transcription Factor Binding Site CAGCTG_V$AP4_Q5 CAGCTG_V$AP4_Q5 7.43E-07 4.55E-04 7.58E-05 5.30E-04 235 1192 "ABR,EMILIN3,NCKAP5,ADCY8,FZD9,CASKIN1,C1QTNF1,SPOP,SRPX,ALK,DOC2A,AMPH,ANK2,SEMA7A,APBA2,APBB2,GAS7,CASK,CADPS,ASPA,PTCH2,CHRD,BACH1,ADGRB3,BCL7A,NRP2,CACNA1G,DDR1,CAMK2G,CAST,HIP1R,CBFA2T2,LRBA,ARHGEF2,CDC25B,ARHGAP33,CDO1,DLGAP1,NUMBL,LHX2,RAB33A,RAB26,ARHGEF6,PCYT1B,CABP1,MAGED1,SMARCAL1,ZNF521,NRG2,NECTIN3,ZNF385A,CPS1,CREM,CRHBP,RNF14,CSF1R,RGS6,IPCEF1,SLITRK5,PPP1R16B,DOCK4,HDAC9,MYADM,SNPH,ARHGAP24,HDAC4,RASSF2,KCTD8,SCRN1,SPOCK2,PABPC5,BRINP1,DCTN1,DLX1,DMD,DMPK,USP3,CD99L2,SLC29A4,DMTF1,DRP2,RCAN1,WDPCP,EDN3,MBNL2,GOLGA7,EIF4G2,ELN,ETV1,RASL12,EYA1,MRVI1,CLVS1,ACSL4,CORO2B,DLC1,FGF1,FGF12,FGF13,FGF14,BAIAP2,ATP5PD,AGAP2,FLNC,NBEA,UFM1,DLL3,TPPP3,MEGF10,GABRA3,IP6K3,TUBA8,MSTN,CYP46A1,GHR,NTNG2,RAB30,POLL,GPD1,GPR34,STMN2,GRIN2D,LINC01089,PSIP1,ATOH8,PADI2,NXPH3,BACH2,AGBL5,SHISA6,IGF1,NKD1,LRRTM1,GPR62,KCNH2,KCNJ16,KCNN2,KCNN3,KIFC3,L1CAM,HECTD2,PIK3AP1,MBNL1,MBP,MEF2C,MEIS2,SCAMP5,MID1,MITF,MXI1,MYCN,MYH3,MYO7A,MYT1,NACA,NFIX,NNAT,NOVA1,KSR2,OGG1,PCDH9,CDK18,PDE3A,NLGN3,PLCB2,PLEC,PCDH18,PMP22,LRRN3,PPP2R5E,PPP3CA,PRKCB,MAPK4,MASP1,CNNM2,PSD,BCAS3,PTH1R,PTK2,RAD51D,RASGRF2,DPF2,RGS12,SALL1,SEMA6D,LRFN5,HES6,TNFRSF19,PPM1E,CPEB3,MYO18A,PREX2,BTBD3,EPN2,SLC12A2,NAPB,ATF7IP,LGI3,CPEB4,CXXC4,TRERF1,ZSWIM8,KDM4C,SPTAN1,CLSTN2,MPRIP,PHLDB1,SEPT3,SUPT5H,TACC1,ANKRD12,PDLIM2,ADGRL3,TCF4,TCF12,DOCK9,TIMP4,NR2E1,TP53BP1,TPM2,EIF4ENIF1,UBE2H,SLC35A4,UBTF,USP1,VGF,LGI4,USP32P2,PRDM8,NAV3,PCBP4,FBXO36,GJC2,JMJD1C,FXR1" Transcription Factor Binding Site CTTTGA_V$LEF1_Q2 CTTTGA_V$LEF1_Q2 1.25E-06 7.64E-04 1.09E-04 7.63E-04 198 981 "KCNH8,ABR,NCKAP5,USP31,SLC24A4,OSBPL6,WDR35,OSBPL8,ALCAM,ABCD2,ARHGAP20,AMPD3,LRCH2,MAP4K3,APBB2,GAS7,PPFIA3,SEMA4G,CASK,CADPS,PTCH2,SLC4A4,DOCK11,ADGRB2,NRP2,BMP7,CA4,CA12,CABP7,SPAG9,USP2,CBFA2T2,CDC25B,NOG,CACNA2D2,FOXN3,CHN2,NDST3,LHX2,CLTC,MAP4K4,ARHGEF6,CNTFR,PCYT1B,COL11A2,ZNF521,IGDCC3,CPS1,CDC42BPB,CREM,HAPLN1,RNF14,CS,SNCAIP,CSNK1G3,SPOCK2,MYEF2,ELMO1,CHRDL1,DLX1,DMD,NYAP1,USP3,EDN3,EIF4G1,EIF4G2,EIF5,TENM1,ERBB4,NCALD,ETV1,EYA1,GMPR2,MRVI1,SCML2,DLC1,PPP1R1B,SEC24B,FGF14,FGFR3,NBEA,AP4B1,MPP6,GABRG2,PPARGC1A,TCERG1,GLI2,GLYR1,RAB30,LINC01089,SOX21,PSIP1,MAP4K5,HAS2,NXPH3,AGBL5,ICA1,NKD1,LRRTM1,ITGAM,TTYH2,LAMP2,LIFR,SMAD1,MBNL1,MBP,MEF2C,MEIS1,MEIS2,KCTD6,KITLG,MID1,PPM1L,MITF,MOV10,MPP2,HS6ST3,NDP,NFIX,NINJ2,OGG1,ZNF827,PAX6,PCDHGC3,PCDH8,PCSK1,ENPP2,PFKFB4,PIK3R1,KCTD15,PLEC,PCDH18,MTRF1L,PPP2R2B,LRRN3,PRKCB,MAPK10,PTPRO,ACSS3,KHDRBS2,RET,FIGN,RFX3,RGS3,RGS12,PBRM1,CYB561D1,ROBO1,PGBD4,FBXW7,EMID1,RTN1,FAM192A,SALL1,SEMA6D,SATB1,SCN2B,TNFRSF19,ARX,CNKSR2,KBTBD4,SLC14A1,ELMO2,SMARCC2,SNAP25,KDM3A,SP4,SPTAN1,CLSTN2,MESP1,ELOVL4,RGL1,STAC2,STX1A,KLHL7,SYNE2,ANKRD28,TCF4,TRIM2,TCF12,PCDHGA4,NSD1,HIF3A,GALNT17,HEY1,NR2E1,TP53BP1,UBE3A,VSNL1,ZIC1,TRIM9,CELF4,SLC30A3,PCBP4,MPPE1,DPF3,AP3B2,CPNE4" Transcription Factor Binding Site CAGGTG_V$E12_Q6 CAGGTG_V$E12_Q6 1.77E-06 1.08E-03 1.26E-04 8.84E-04 358 1956 "ABR,ASIC1,EMILIN3,ADCY8,AXIN2,ADRA1B,ADRB2,MTUS1,KLHL13,CASKIN1,KIAA1324,C1QTNF1,SEMA6A,ALCAM,DOC2A,AMPD2,ANK2,MAP4K3,PKP4,KCNAB2,EPB41L5,USP37,SEMA4G,MADD,ARRB2,ADGRB2,NRP2,BMP7,BMPR1B,JAZF1,CACNA1G,DDR1,CALB1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2G,SLC25A14,CAST,RHBDL1,SPAG9,CBLN1,KYAT1,USP2,SYNGR3,ENTPD2,DGKI,AP4M1,CDH2,MAGI1,TIGD7,CRLF1,UBE2L6,NUMBL,CACNA2D2,PLEKHB1,B4GALT6,SLIT2,RAB33A,NRXN3,PPT2,RAB26,CCDC151,COL9A3,COL11A2,SLC4A8,TBPL1,ZNF521,NRG2,AKAP12,CRMP1,NCOR1,SNCAIP,RGS6,LRIG1,SOCS5,RIMS4,PHACTR3,PPP1R16B,UBXN2A,GREB1,RIMS2,HDAC9,ARHGAP32,ARHGAP24,RASSF2,DGKG,DAPK1,SPOCK2,GIT2,ARMCX2,DCTN1,ELMO1,C2CD2L,KLHL3,RHOBTB1,SV2B,WDR20,DMD,DMPK,NYAP1,CDON,SHANK1,SLC12A6,DRP2,DTNB,DUSP9,WDPCP,EDN1,PHC2,CNNM1,HEYL,PLXNC1,RGS17,ELN,EPB41,RASGRP2,ERBB4,ETV1,RASL12,EYA1,ARMCX1,CLVS1,ACSL4,PTK2B,CORO2B,FGF1,FGF11,FGF12,FGF13,PRKAG2,POLK,HPCAL4,IP6K2,AGAP2,SYNCRIP,AGAP3,FLNC,SYT3,NBEA,CELF1,FUT9,FYN,GABRA3,CHL1,GABRG2,GAD1,IP6K3,IQGAP2,GATM,GCK,PCDH17,PPARGC1A,RUNDC3A,NTNG2,GLI2,HTATSF1,GNAO1,GPD1,TDRKH,GPR37,STMN2,PLCD4,GRIK5,GRM8,ZNF496,LINC01089,CLASRP,KAT7,AP4S1,PSIP1,GUCY1A1,GUCY1B1,ZDHHC15,NEGR1,MYLK2,RBPJ,IL6R,ITGA7,ITPKA,KCNB1,KCND1,KCND2,KCNH2,KCNN2,KCNN3,KCNQ3,KIT,KTN1,LMO2,HECTD2,PIK3AP1,MAPT,MARK1,MATK,CHST6,ADAM11,MEF2C,MEIS2,SCAMP5,MID1,MMP16,GIT1,HS6ST3,NACA,NBL1,NCAM2,NDP,NEFH,NFIX,NNAT,CNOT4,NOVA2,NPTX1,NPTX2,NRCAM,NTRK2,NTRK3,ZNF827,PALM,PAX6,CDK18,PDE1C,PDE3A,PDE4B,ENPP2,PFKFB2,SERPINI1,PIK3R1,SNX10,KCTD15,PLCB2,PLEC,FXYD1,SLC25A23,PMP22,STRN3,MAGEL2,ING3,EPB41L4B,FA2H,PPARA,PPP2R2B,RASGEF1B,CEP41,PKIA,MAPK10,PRPH,MASP1,CNNM2,PSD,GDPD2,ANKHD1,STK32A,PTPRB,EML5,PTPRO,TTC13,STRC,OXR1,RASGRF2,KHDRBS2,TSPY26P,REV3L,RFX3,RGS3,PBRM1,LGI2,ZNF532,RORB,KCNIP1,RTN1,RYR3,TRAPPC13,MAPK12,LRFN5,SCN2B,HES6,SMPD3,ZNF821,CPEB3,MYO18A,CNKSR2,ABLIM3,BTBD3,SLC6A11,SMARCC2,TTC17,SNAP25,SNCA,KIF13A,TRERF1,SOX3,SOX15,UNC5B,ARHGAP26,SPTAN1,SPTB,LMO3,CAMTA2,SSTR1,NKAIN2,STX1A,SEPT3,STXBP1,SYNE2,VPS13A,ADAMTS17,PLCB1,SYT1,COBL,TACC1,TACR1,TAL1,PDLIM2,FBXW11,TCEA1,SYNE1,PCDHA6,PCDHA1,HIF3A,SIRT1,CHST8,THRA,TIAM1,NR2E1,TP53BP1,RASD2,WBP2,TRPS1,SSBP2,HSPBP1,CLHC1,HIRA,UBTF,USP1,MGAT5B,VGF,KCNK12,ZIC2,NDRG4,CELF4,ZNF189,DPYSL5,SH3GLB2,SLC30A3,PRDM10,SEMA3B,GAL3ST3,FIP1L1,PCBP4,RTN4,GJC2,JMJD1C,NETO2,DPF3,JPH3" Transcription Factor Binding Site GTTRYCATRR_UNKNOWN GTTRYCATRR_UNKNOWN 1.86E-06 1.14E-03 1.26E-04 8.84E-04 40 128 "CASKIN1,DOC2A,ANK2,NUMB,ATP1A3,CAMK2A,PPT2,HDAC4,SPATA2,ELMO1,SHANK1,KATNAL1,TBC1D16,HPCAL4,AGAP2,FYN,CHL1,GDF1,POLL,GRIN2D,NIM1K,MPP2,NLGN3,FXYD1,PDZRN4,MAPK10,PSD,ZNF532,PNMA8A,PPM1E,DHX30,FAM214B,FAIM2,SOX3,LMO3,ST5,CHST8,TP53BP1,ZNF24,SMARCAD1" Transcription Factor Binding Site V$ZIC2_01 V$ZIC2_01 2.76E-06 1.69E-03 1.69E-04 1.18E-03 55 201 "ABR,MTUS1,PCDH10,OGT,PI16,PHF12,PKP4,PRX,PTCH2,CALB1,USP2,NOG,CLTC,CCDC151,ZNF385A,PPP1R16B,RASSF2,EDN3,KLHL5,TENM1,CERCAM,FGF12,FGF13,SYNCRIP,ATP2C1,SDCBP2,GABRG2,GHR,GNAO1,GRIN2D,ZDHHC15,LRRTM1,KCND2,KCNK3,MAP4,MYCN,NELL2,NFYA,OGG1,GPR85,NLGN3,PPP2R5E,MAPK10,ZCWPW1,RBBP6,FBXW7,DHX30,TRERF1,FNBP1,SOX15,PDLIM2,TP53BP1,CRB2,PRDM10,SEMA3B" Transcription Factor Binding Site V$E47_02 V$E47_02 4.46E-06 2.73E-03 2.48E-04 1.74E-03 54 199 "ABR,KLHL13,AMPH,SEMA4G,CALB1,NUMBL,PLEKHB1,RAB33A,SNCAIP,RIMS2,HDAC9,ARMCX2,RHOBTB1,PARD6A,DMD,DMPK,DUSP9,FGF11,FGF13,CELF1,GATM,PCDH17,AP4S1,KCNN2,LMO2,MEF2C,MEIS2,MMP16,GIT1,NPTX2,PDE4B,PLEC,STRN3,PPP2R2B,LRRN3,CEP41,ZNF532,TRAPPC13,MAPK12,HES6,MYO18A,BTBD3,SNAP25,TRERF1,UNC5B,SYNE2,TAL1,PCDHA6,PCDHA1,THRA,TPM2,CELF4,JMJD1C,JPH3" Transcription Factor Binding Site V$AMEF2_Q6 V$AMEF2_Q6 1.33E-05 8.15E-03 6.79E-04 4.75E-03 55 211 "MTUS1,SLC4A4,NRP2,JAZF1,USP2,ARHGEF2,NOG,CNTN1,PCYT1B,COL9A1,CRHBP,HAPLN1,SNCAIP,PPP1R16B,HDAC9,DCTN1,C2CD2L,RHOBTB1,CHRDL1,EDN1,MBNL2,ETV1,EYA1,TBC1D16,FGF13,ATP5PD,FLT1,MSTN,PPARGC1A,GNAO1,HAS2,ITGA7,MID1,MYO9A,NDP,ZDHHC8,PDZRN4,PPP2R2B,USP47,ZCWPW1,RBBP6,RFX3,RGS3,CYB561D1,RORB,RTN1,SALL1,SOX15,SPTAN1,TACR1,FBXW11,CLASP1,TPM2,GAL3ST3,JMJD1C" Transcription Factor Binding Site TGACCTY_V$ERR1_Q2 TGACCTY_V$ERR1_Q2 1.52E-05 9.30E-03 6.82E-04 4.77E-03 167 834 "ABR,ASIC1,NCKAP5,NDRG2,FZD9,USP31,SLC24A4,MTUS1,AK2,AMPD3,AMPH,CDC42BPA,SEMA7A,FGD2,MAP4K3,APBA2,USP37,MADD,TMEFF1,CDK13,ATP1A3,ADAM15,BMPR1B,NAE1,CAMK2G,SPAG9,USP2,CD86,SYNGR3,DGKI,NOG,LHX2,CLTC,CCDC151,CNTFR,COX4I1,RNF14,CS,PHACTR3,PPP1R16B,RIMS2,BOC,MYADM,SNPH,ARHGAP24,KIAA0586,DCTN1,FBXL5,PARD6A,DLX1,DMD,DNM1,DMPK,NYAP1,USP3,DTNB,ABCC5,RCAN2,RASGRP2,ERBB4,MRPL37,PIPOX,VPS26C,DNAJC27,EXTL2,MRVI1,FGF12,FGFR3,FHL1,HPCAL4,AGAP2,AGAP3,DCTN2,TPPP3,MPP6,GABRA3,GABRG2,PPARGC1A,NTNG2,TCERG1,HTATSF1,GRM8,LINC01089,MAP4K5,SYNPO,USP51,HP,DHX35,IDH3A,ITGA7,ITPKA,CDH20,KCNN1,KCNN3,KIF5A,STMN1,LIFR,HECTD2,MEF2C,MEIS2,KCTD6,SCAMP5,PPM1L,MITF,MPP2,NFIX,NFYA,NNAT,NPTX2,PAX6,PCSK5,CCSER2,PLEC,FXYD1,PPM1B,PPP3CC,MASP1,STK32A,CRTAC1,RGS3,ZNF532,PNMA8A,RPE,RPS6KA2,PLPPR3,SATB1,LRFN5,PPM1E,ARX,SLC4A3,PEX26,BTBD3,PKNOX2,SLC6A8,RADIL,SMARCC2,OGDHL,MBD5,TRERF1,SP2,SPTAN1,LMO3,ST5,STAC2,ANKRD28,SLC37A2,ASTN2,MLST8,SIK3,TEK,NACC2,TLR4,TP53BP1,TPM2,NR2C2,KCNE5,UCHL1,BCL2L13,PLPPR2,TBC1D15,VSNL1,SLC30A3,PCBP4,MRPL47,ADAMTSL3,JMJD1C,DPF3" Transcription Factor Binding Site V$FOXO4_01 V$FOXO4_01 1.56E-05 9.55E-03 6.82E-04 4.77E-03 52 197 "C1QTNF3,CADPS,LINC00173,SLC4A4,STX16,MTMR2,LDB2,CBFA2T2,CACNA2D2,ZNF521,SNCAIP,CSNK1G3,SLITRK5,HDAC9,PITPNC1,DMD,NYAP1,SLC12A6,ABCC5,EIF4G1,EPHB1,ETV1,EZH1,FGF14,BRD8,ATOH8,NIM1K,IL6ST,MBNL1,MEIS2,MXI1,NTRK3,PALM,PDE4D,ENPP2,PFKFB3,PLCB2,PTH1R,SH3GL3,ABLIM3,ATF7IP,TRERF1,KDM3A,NMNAT2,ST5,ANKRD28,SATB2,PCDHB15,THRA,TRPS1,UBE2H,VLDLR" Transcription Factor Binding Site AACTTT_UNKNOWN AACTTT_UNKNOWN 1.94E-05 1.19E-02 7.91E-04 5.54E-03 282 1531 "KCNH8,NCKAP5,ADCY6,ADCY8,AXIN2,ADRA1B,ADRB2,SLC24A4,OSBPL6,SPARCL1,SEMA6A,ALCAM,PCDH10,UNC79,ALK,BEGAIN,MAP4K3,APBB2,CPNE5,CDC14B,TMEFF1,CADPS,DOCK11,ADAM23,ADGRB2,ADGRB3,BCHE,BCS1L,NRP2,ARHGEF7,JAZF1,CACNA1G,CA12,CALB1,CALB2,CABP7,CALM1,PTBP2,CAMK2A,SPAG9,LDB2,DGKI,ARHGEF2,LARGE1,MAGI1,NOG,FOXN3,CHN1,CHN2,NDST3,LHX2,CLCN3,CNTFR,CNTN1,CABP1,COL4A5,COL9A1,ZNF521,CREM,CRHBP,HAPLN1,RNF14,SNCAIP,PHACTR3,CNTNAP2,SLITRK5,GREB1,PYGO1,DOCK4,HDAC4,RASSF2,PITPNC1,ELMO1,FBXL5,KLHL3,DDX46,RHOBTB1,CHRDL1,DLX1,GRIN3A,DMD,CPEB2,TOM1,ABCC5,EDIL3,PHC2,MBNL2,EGR3,PLXNC1,RASA4,EIF4G1,EIF5,ING4,EMX2,RCAN2,EPHB1,ERBB2,ERBB4,NCALD,IGSF6,ETV1,EXTL2,EYA1,MRVI1,CLVS1,ACSL4,FCGRT,PPP1R1B,SEC24B,OLFM1,FGF12,FGF13,FGF14,FGFR1,PRKAG2,FOXO3,FUT9,MPP6,GABRA3,GABRG1,IQGAP2,MSTN,SESN1,GHR,PPARGC1A,NTNG2,RAB30,GNG4,GPR37,SOX21,NXPH3,PACSIN2,ELOVL5,IGF1,NKD1,ZIC5,IL6ST,LRRTM1,KCNN2,KIT,LAMP2,SFXN5,HECTD2,LSAMP,SMAD1,MBNL1,LRP1B,SHC3,MEF2C,MEIS1,MEIS2,KITLG,MID1,MITF,MMP16,MN1,MPP2,GIT1,MXI1,MYT1,NCAM2,NDP,NELL2,NOVA1,NPTX2,NTRK3,NUCB2,ZNF827,PAX6,PCDHGC3,PCDH8,PCDH9,PCSK1,PCSK5,CDK18,PDE4B,PDE4D,GPR85,NLGN3,SERPINI1,PIK3R1,CCSER2,KCTD15,PLCL1,PLIN1,PCDH18,PDZRN4,PSAT1,ING3,SH3KBP1,PPP2R2B,PRKAB2,PRKACB,MAPK3,MAPK10,RELN,PTK2,ZSCAN32,PTPRG,OXR1,CRTAC1,RFX3,RGS3,PRIMA1,RORB,FBXW7,RPS6KA2,STK32B,KCNIP1,RYR3,FAM192A,SALL1,SEMA6D,SATB1,SCN8A,TNFRSF19,SCAF8,PPM1E,MYO18A,CNKSR2,NLGN1,DZIP1,BTBD3,SLC6A11,SEPHS1,SLC12A2,ELMO2,EPC1,CXXC4,TTC17,SNCA,MBD5,TRERF1,SOX3,KDM3A,SP4,SPP1,SPTB,SPART,LMO3,CLSTN2,ELOVL4,TTBK2,STAC2,STX1A,SYNE2,PLCB1,TACR1,TAL1,TCF4,TRIM2,TCF12,SYNE1,NSD1,ZFPM2,CHST8,TIMP4,NR2E1,PARD3,TRPS1,TSC1,SSBP2,TOM1L2,VIPR2,VLDLR,WNT7A,KCNK12,XPO1,ZIC1,CELF4,ADAMTS9,NAV3,FIP1L1,ITM2C,FAM13C,MRPL47,KAT6A,ADAMTSL3,NETO2,NETO1,DPF3,CPNE4" Transcription Factor Binding Site V$HP1SITEFACTOR_Q6 V$HP1SITEFACTOR_Q6 2.12E-05 1.30E-02 8.11E-04 5.67E-03 50 189 "ZBTB10,CA4,NOG,NRXN3,MAP4K4,CNTFR,NCOR1,CS,SNCAIP,HDAC9,PARD6A,CHRDL1,DLX1,DMD,DMTF1,DPYSL2,MBNL2,EIF4G2,CALCRL,NCALD,POLK,IP6K2,SYNCRIP,GCNT2,MSTN,ADAM28,IGF1,SFXN5,SMAD1,MBNL1,ADAM11,MEIS1,NFIX,ZNF827,PIK3R1,SCHIP1,LRRN3,PRKACB,MAPK10,RGS3,LRFN5,PREX2,MPRIP,ANKRD28,PJA1,PUM2,PCDHA7,VLDLR,XPO1,ZIC1" Transcription Factor Binding Site YGCANTGCR_UNKNOWN YGCANTGCR_UNKNOWN 2.76E-05 1.69E-02 9.72E-04 6.80E-03 32 104 "SEMA7A,STX16,ADGRB2,SYNJ1,CAST,NRXN3,CLTC,MAGED1,EIF4G2,PLEKHA1,EPHB1,FGF13,FGFR1,NOP56,OGA,KIAA1841,ZDHHC15,KCNN2,SFXN5,MAT2A,NNAT,NOVA1,NLGN3,PNMA3,ELP2,SARS,LRFN5,FBXO11,ELOVL4,VSNL1,KLC2,TRIM9" Transcription Factor Binding Site GCANCTGNY_V$MYOD_Q6 GCANCTGNY_V$MYOD_Q6 3.03E-05 1.86E-02 9.72E-04 6.80E-03 146 721 "ABR,ADCY6,AXIN2,FZD9,MTUS1,SPOP,ALK,DOC2A,ANK2,FGD2,PKP4,APBB2,PPP4R4,CASK,CADPS,CHRD,ATP1A3,ATP2A2,ADGRB2,BCL7A,CALM1,USP2,CRLF1,NUMBL,SLIT2,RAB33A,NRXN3,CLCN3,ARHGEF6,CABP1,SLC4A8,MAGED1,TBPL1,ZNF521,ZNF385A,CSF1R,PHACTR3,PPP1R16B,HDAC9,SNPH,ARHGAP24,RASSF2,PABPC5,BRINP1,C2CD2L,DMD,DMPK,SLC29A4,DRP2,HEYL,MBNL2,EIF4G2,GPHN,ETV1,EYA1,CLVS1,FGF11,FGF12,FGF13,FGFR1,PRKAG2,NBEA,DLL3,FYN,MEGF10,GABRA3,PPARGC1A,GPD1,TDRKH,STMN2,GRIN2D,AP4S1,PSIP1,GUCY1A1,ATOH8,MUM1,AGBL5,NEGR1,ITGA7,KCND2,GPR62,KCNH2,KCNN2,KCNN3,MBNL1,ADAM11,MPP2,GIT1,MYH3,MYO7A,MYT1,NEFH,NNAT,NOVA1,NTRK3,PCDH9,STRN3,FA2H,LRRN3,PPP3CA,RASGEF1B,PRKCB,MASP1,PSD,BCAS3,PTH1R,EML5,OXR1,RGS3,RGS12,PBRM1,TRAPPC13,LRFN5,SCN8A,HES6,TNFRSF19,MYO18A,CNKSR2,PREX2,RADIL,ATF7IP,TRERF1,SOX15,SPTB,LMO3,NKAIN2,MPRIP,COBL,TACC1,TACR1,ADGRL3,TBL1X,TCF12,SYNE1,HIF3A,NR2E1,RASD2,TPM2,HIRA,EIF4ENIF1,XPO1,CELF4,DPYSL5,SLC30A3,PCBP4,DPF3" Transcription Factor Binding Site GGGAGGRR_V$MAZ_Q6 GGGAGGRR_V$MAZ_Q6 3.04E-05 1.86E-02 9.72E-04 6.80E-03 330 1838 "ASIC1,NDRG2,ADORA2A,MTUS1,TBC1D14,KIAA1324,ALCAM,SRPX,BEGAIN,AMPD2,AMPH,SEMA7A,FGD2,MAP4K3,PHF12,PKP4,PPFIA3,CASK,TMEFF1,SPTBN4,ARRB2,CADPS,ASGR1,ZBTB10,CHRD,ATP1A1,ATP1A3,STX16,ATP2A2,ADAM15,AZGP1,ADGRB2,HCN2,BMP7,SYNJ1,JAZF1,CACNA1G,WASF1,CAMK2G,SPAG9,KYAT1,USP2,SLC16A4,CDH2,KCNAB3,NUMBL,PLEKHB1,CPNE6,RAB33A,PPT2,CLTC,HECTD1,CNN3,CNTFR,PCYT1B,CABP1,COL4A5,COL11A2,MAGED1,ZNF521,ZNF385A,CLOCK,CREM,AKAP12,CRMP1,HAPLN1,NCOR1,CS,SEC24C,CSNK1E,PHACTR3,CNTNAP2,SLITRK5,PPP1R16B,DOCK4,MYADM,SNPH,ARHGAP24,HDAC4,RASSF2,MATR3,DGKG,BRINP1,PITPNC1,C2CD2L,KLHL3,SV2B,CHRDL1,DLX1,DMD,DMPK,NYAP1,RPS6KL1,CDON,SHANK1,CASP8AP2,ARRDC4,DUSP9,PHC2,CNNM1,EGR3,PLXNC1,RASA4,EIF4G1,EIF4G2,CERCAM,DCTN4,EMX2,RASGRP2,GPHN,SRRM1,APC2,ETV1,EYA1,F5,DLC1,FGF11,FGF13,FGF14,FGFR1,HPCAL4,AGAP2,SYNCRIP,FOXO3,FLNC,SYT3,CELF1,DLL3,HHIPL1,FYN,GABBR1,GABRA3,CHL1,GABRG2,CPLX2,TUBA8,SESN1,PCDH17,RUNDC3A,MSL3,GNAL,LOXL3,GNAO1,FERMT2,ADAP1,STMN2,GRIN2D,ZNF496,GSN,SOX21,PSIP1,NXPH3,FRMD3,BACH2,GABARAPL2,AGBL5,HNF4G,ZDHHC15,USP51,MYLK2,RBPJ,INSM1,LRRTM1,ITPKA,JAK2,KCND1,KCNH2,LAMP2,PIK3AP1,MAP4,MAPT,CHST6,ADAM11,MEIS1,MEIS2,MGAT3,MITF,MOV10,MSI1,ADAM22,HS6ST3,MXI1,MYCN,MYT1,NCAM2,NEFH,NF1,NFIX,NNAT,CNOT4,NPY,NOVA2,NPTX1,NTRK2,NTRK3,OGG1,PAX6,PCDH9,NLGN3,SERPINI1,TMIE,PLCB2,PLEC,PLIN1,FXYD1,SLC25A23,PURG,EPB41L4B,PPP2R2B,PPP2R2C,PPP2R5E,PPP3CA,MAPK3,MAPK7,MAPK10,PRPH,CNNM2,PSD,VPS13C,LAMA1,GDPD2,SNRK,PTH1R,PTPRG,RAD17,RAP1GDS1,ZCWPW1,ZDHHC14,GAL3ST4,DPF2,FIGN,RFX3,RGS3,ZNF532,TMLHE,CARF,CYB561D1,RORB,RPL15,FBXW7,SALL1,MAPK12,SATB1,LRFN5,SCN8A,SMPD3,ZNF821,SCAF8,PPM1E,FBXO11,CNKSR2,NLGN1,DZIP1,EPN2,FAM214B,KDM4D,SLC12A4,SLC14A1,GKAP1,SMARCA4,SMARCD3,SNAP25,SNCA,KIF13A,TRERF1,TSNAXIP1,SOX11,SOX15,KDM3A,SP4,NMNAT2,LMO3,CAMTA2,ST5,ELOVL4,RGL1,STAC2,PHLDB1,SULF2,SYNE2,ARC,SYN2,PJA1,TAF9,ADGRL3,KLHL4,TCF4,TCF12,SYNE1,TNS2,HIF3A,ZFPM2,CHST8,THRA,NR2E1,TPM2,CHST5,TRPS1,KCNE5,CA14,TSC1,SSBP2,UBE2H,UBTF,VGF,VLDLR,WNT7A,WRN,KLC2,NPDC1,XPO1,PCDH20,ZIC2,ZNF24,ZNF32,CRB2,CELF4,FSTL5,PRTFDC1,SLC38A1,PRDM8,ADAMTS9,KCNAB1,ITM2C,PCBP4,ST7,FBXO36,NETO1,SENP7,JPH3" Transcription Factor Binding Site RTTTNNNYTGGM_UNKNOWN RTTTNNNYTGGM_UNKNOWN 3.18E-05 1.94E-02 9.72E-04 6.80E-03 37 128 "OGT,BACH1,SPAG9,CFL2,PCYT1B,HAPLN1,DDX46,DMD,RCAN1,EGFR,ETV1,EYA1,PPP1R1B,GABRG2,MSTN,HAS2,KCTD6,MITF,NDP,NOVA1,SLC11A2,NTRK2,GPR85,PPP2R5E,PTPRG,RFX3,RGS3,FBXO11,ZNF423,ANKRD28,PUM2,TRPS1,ZIC1,ZIC2,CELF4,NAV3,DPF3" Transcription Factor Binding Site YNGTTNNNATT_UNKNOWN YNGTTNNNATT_UNKNOWN 3.68E-05 2.25E-02 1.05E-03 7.37E-03 68 286 "AXIN2,KLHL13,PCDH10,DPP10,PKP4,ASPA,NUMB,ATP2A2,CACNA1G,CALM1,CBLN1,NOG,FOXN3,CHN2,LHX2,NRXN3,PCYT1B,COL9A1,ZNF521,CNTNAP2,CYBB,DOCK4,DCTN1,ELMO1,CHRDL1,GRIN3A,DMD,ETV1,EYA1,ACSL4,DLC1,TPPP3,CHL1,GABRG2,GNAO1,KAT7,INSM1,MITF,MXI1,NFIX,NTRK3,OGG1,PDE1C,ENPP2,PIK3R1,KCTD15,PDZRN4,PPP2R5E,CEP41,PTPRD,RASGRF1,FIGN,RGS3,RORB,SATB1,CPEB4,KIF13A,SP4,LMO3,PLCB1,TAL1,TPCN2,TCF12,ZFPM2,TPM2,ZIC2,CELF4,JMJD1C" Transcription Factor Binding Site V$RFX1_02 V$RFX1_02 3.79E-05 2.32E-02 1.05E-03 7.37E-03 52 203 "CASKIN1,TRMT9B,ANK2,GAS7,ATP1A3,BAIAP3,KALRN,CAMK2A,PPT2,RGS6,PUM1,HDAC4,SPATA2,ELMO1,DMD,ARRDC4,NCALD,KATNAL1,TBC1D16,PTK2B,HPCAL4,AGAP2,CINP,CHL1,POLL,GRIN2D,NIM1K,ITPKA,KCNJ16,MPP2,FXYD7,TMIE,PLEC,FXYD1,LRRN3,CEP41,MAPK10,HYDIN,PSD,ZNF532,PPM1E,BTBD3,BDP1,TSNAXIP1,KDM3A,SYT5,ITGB3BP,ICAM5,TP53BP1,TRPS1,CRB2,SH3GLB2" Transcription Factor Binding Site V$E47_01 V$E47_01 4.37E-05 2.67E-02 1.14E-03 7.98E-03 52 204 "EMILIN3,KLHL13,SORCS2,SPOP,ARRB2,CHRD,CALB1,KALRN,CAMK2A,CAMK2G,CDH2,NUMBL,CACNA2D2,RAB26,AKAP12,GIT2,CHRDL1,DRP2,DUSP9,EPB41,PTK2B,FLNC,GABRG2,PCDH17,GPR37,PSIP1,RBPJ,KCNB1,KCNH2,MYO7A,NBL1,PLEC,EPB41L4B,PPP2R2B,CNNM2,TTC13,KHDRBS2,ZNF532,HES6,ABLIM3,TTC17,SPTAN1,LMO3,VPS13A,PLCB1,NSD1,THRA,EIF4ENIF1,KCNK12,DPYSL5,SH3GLB2,NETO2" Transcription Factor Binding Site V$CDPCR3HD_01 V$CDPCR3HD_01 4.47E-05 2.74E-02 1.14E-03 7.98E-03 50 194 "ASIC1,TBC1D14,DPP10,LINC00173,SLC25A14,CBFA2T2,NOG,FOXN3,CPNE6,RAB33A,CREM,HAPLN1,BRINP1,DMD,DPYSL2,DRP2,WDPCP,EGR3,EIF4G2,ETV1,EYA1,FYN,GCK,NTNG2,STMN2,GRIK4,HNF4G,NEGR1,ITGA7,KCND1,KCNH2,SMAD1,MEIS1,MN1,GIT1,MYT1,NFIX,NOVA1,ZNF827,SERPINI1,RASGRF1,GAL3ST4,ROBO1,FBXW7,BTBD3,CLSTN2,MGAT5B,VGF,CELF4,ST7" Transcription Factor Binding Site RYTGCNWTGGNR_UNKNOWN RYTGCNWTGGNR_UNKNOWN 6.92E-05 4.24E-02 1.69E-03 1.19E-02 28 90 "KIAA1324,TRMT9B,OGT,ANK2,DDR1,CAMK2A,SHANK1,ARRDC4,KATNAL1,PTK2B,HPCAL4,POLL,GRIN2D,KCNN2,FXYD7,NNAT,NLGN3,FXYD1,PPP3CA,MAPK10,PNMA8A,PPM1E,BTBD3,CHST8,ITGB3BP,TIMP4,TP53BP1,ZNF24" Transcription Factor Binding Site V$HNF6_Q6 V$HNF6_Q6 7.87E-05 4.82E-02 1.85E-03 1.30E-02 50 198 "MTUS1,ADGRB3,JAZF1,CAST,CHN2,DGKG,BRINP1,DCTN1,EDN1,RCAN2,ATP6V1H,MSTN,PCDH17,GNAO1,GABARAPL2,HNF4G,MAT2A,MBNL1,MEF2C,MITF,MN1,NFIX,NOVA1,OGG1,ZNF827,GPR85,PIK3R1,KCTD15,PDZRN4,LRRN3,GAL3ST4,ZNF532,NEK11,SALL1,FBXO11,PREX2,SLC12A2,TTC17,CLSTN2,POGZ,SST,SULF2,ANKRD28,NSD1,THRA,NR2C2,VLDLR,ZIC1,CELF4,KCNAB1" Transcription Factor Binding Site CATTGTYY_V$SOX9_B1 CATTGTYY_V$SOX9_B1 8.20E-05 5.02E-02 1.86E-03 1.30E-02 68 293 "NDRG2,KLHL13,TBC1D14,ADGRF5,TRMT9B,ADAM15,GPC2,SPAG9,CBFA2T2,NUMBL,CFL2,CHN1,NDST3,MAP4K4,CNN3,ZNF521,CLOCK,CRMP1,PPP1R16B,GREB1,DOCK4,HDAC9,RASSF2,MAML1,DLX1,DMD,EDN1,PLEKHA1,DLC1,OLFM1,FGFR1,FGFR3,CHL1,GNAO1,PSIP1,IGF1,KCNN2,STMN1,MBP,MEIS1,MID1,MITF,MN1,GPR85,PCDH18,MAPK3,LAMA1,MYO18A,FBXO11,ABLIM3,SEPHS1,RADIL,LMO3,TCF4,TRIM2,TNS2,CHST8,TIAM1,UBE3A,OSBP2,MGAT5B,VLDLR,DPYSL5,PRDM8,PCBP4,FAM13C,KAT6A,GJC2" Transcription Factor Binding Site AAAYRNCTG_UNKNOWN AAAYRNCTG_UNKNOWN 8.56E-05 5.24E-02 1.87E-03 1.31E-02 72 315 "APBB2,ADGRB3,BMPR1B,HIP1R,CDH2,B4GALT6,CLTC,CNTN1,PCYT1B,COL4A5,ZNF521,MAML1,DGKB,SPOCK2,KLHL3,DMD,PHC2,EIF5,RGS17,EMX2,ERBB4,EYA1,FGF12,FGFR1,IP6K2,MPP6,GABRA3,PCDH17,DHRS4,RAB30,AP4S1,SOX21,ATOH8,IGF1,KCNN3,PACRG,MAP2,MAP6,SHC3,MEIS1,KITLG,MID1,NEK1,NTRK2,GPR85,PLEC,PCDH18,PDZRN4,STRN3,PPP2R5E,PPP3CA,PTH1R,TSPY26P,RTN1,SEMA6D,SCN8A,ARX,MYO18A,BTBD3,NAPB,EPC1,TTC17,ANKRD28,ANKRD12,PDLIM2,ZFPM2,TRPS1,SSBP2,USP1,ZIC1,NAV3,RNF146" Transcription Factor Binding Site V$CART1_01 V$CART1_01 1.28E-04 7.80E-02 2.69E-03 1.88E-02 46 181 "ASIC1,MTUS1,KLHL13,ARRB1,CALB2,CFL2,RCHY1,NECTIN3,SLITRK5,RIMS2,CHRDL1,RCAN1,WDPCP,HIPK3,MBNL2,EYA1,FGF13,FYN,CYP46A1,GRM8,ADAM11,MEF2C,MEIS2,MID1,MYT1,NFIX,NPTX2,OGG1,GPR85,KCTD15,PDZRN4,CRTAC1,RFX3,SALL1,LRFN5,PPM1E,SEPHS1,ZNF423,SPTB,LMO3,POGZ,PCDHB15,ZFPM2,PRDM10,NETO1,JPH3" Transcription Factor Binding Site RGAANNTTC_V$HSF1_01 RGAANNTTC_V$HSF1_01 1.75E-04 1.07E-01 3.54E-03 2.48E-02 78 355 "ADCY6,ADCY8,SLC24A4,PCDH10,UNC79,OGT,LINC00173,ATP1B3,ADAM15,SYNJ1,CACNA1A,HIP1R,SPAG9,CACNA2D2,PLEKHB1,NRXN3,PPT2,MAP4K4,CNTFR,COL4A5,CREM,GREB1,RIMS2,HDAC4,DAPK1,DBI,DMD,SHANK1,DMTF1,ABCC5,MBNL2,EGR3,PLXNC1,EIF4G2,RASGRP2,CLVS1,FHL1,FLNC,CAMKK2,ATP2C1,GAD1,CYP46A1,RUNDC3A,GRM8,GSN,CLASRP,ELOVL5,HSPA1L,SHISA6,RBPJ,IL6ST,SMAD1,MAP2,MAP6,MARK3,MAT2A,SHC3,MEF2C,MMP16,HS6ST3,NNAT,ENPP2,PLEC,PPP2R2C,RFX3,CARF,RORB,RTN1,TRERF1,SP4,ANKRD28,CHST8,TPM2,TRPS1,EIF4ENIF1,XPO1,ADAMTS9,NETO2" Transcription Factor Binding Site YCATTAA_UNKNOWN YCATTAA_UNKNOWN 1.79E-04 1.10E-01 3.54E-03 2.48E-02 97 462 "ADRA1B,KLHL13,CPNE5,SEMA4G,TMEFF1,DOCK11,ADGRB2,JAZF1,CA4,KALRN,LARGE1,FOXN3,ARHGAP22,CCDC151,COL9A1,CPS1,CLOCK,PPP1R16B,BOC,RASSF2,PABPC5,RHOBTB1,DMD,HIPK3,KLHL5,MBNL2,TENM1,EMX2,EYA1,SCML2,CHST15,FGF13,SEC23B,IP6K2,AGAP3,MPP6,MSTN,RAB30,PLCD4,GRM8,AP4S1,BACH2,SHISA6,KCND1,KCNH2,LIMS1,SYTL4,MARK1,AQP11,MITF,ADAM22,MYT1,NDP,NF1,NOVA1,NPTX2,ZNF827,PDE4D,GPR85,NLGN3,KCTD15,PLIN1,STRN3,LRRN3,PTK2,PTPRO,RASGRF1,RASGRF2,RBBP8,DPF2,ZNF532,CYB561D1,ROBO1,RORB,RTN1,SATB1,KIF21A,PPM1E,TRERF1,ZNF423,LMO3,SSTR1,STAC2,ANKRD28,KLHL4,SATB2,PCDHGB7,DOCK9,NSD1,PCDHAC2,CHST8,NR2E1,TPM2,TRPS1,MGAT5B,P2RY12,CELF4" Transcription Factor Binding Site V$CDPCR1_01 V$CDPCR1_01 1.88E-04 1.15E-01 3.57E-03 2.50E-02 31 109 "TBC1D14,DPP10,LINC00173,NOG,CPNE6,NRXN3,PPT2,CREM,DGKB,BRINP1,WDPCP,ETV1,FGF12,NTNG2,STMN2,GRIK4,KAT7,ITGA7,KCND1,MBNL1,MEIS1,MN1,NOVA1,ZNF827,SERPINI1,BTBD3,THRA,MGAT5B,CELF4,TMEM237,ST7" Transcription Factor Binding Site V$MYOD_01 V$MYOD_01 1.99E-04 1.22E-01 3.57E-03 2.50E-02 50 205 "KIAA1324,SORCS2,SPOP,ALCAM,BACH1,CALB1,CAMK2A,CBFA2T2,ARHGEF2,CRLF1,CACNA2D2,RAB26,COL11A2,RIMS2,ELMO1,USP3,DRP2,PLXNC1,ETV1,PTK2B,FGF11,AGAP3,CELF1,GABRA3,GCK,PPARGC1A,GPR37,GRIK5,PSIP1,IGF1,KCNB1,KCNN2,KCNN3,KTN1,NTRK2,EPB41L4B,CEP41,CNNM2,PSD,GDPD2,HES6,FRMPD1,ABLIM3,KDM4C,GALNT17,WBP2,KCNE5,EIF4ENIF1,USP32P2,GAL3ST3" Transcription Factor Binding Site V$RORA1_01 V$RORA1_01 2.04E-04 1.25E-01 3.57E-03 2.50E-02 49 200 "NCKAP5,NDRG2,ARNTL,CACNA1A,CAMK2B,SPAG9,LDB2,KCNAB3,LARGE1,NOG,CNTFR,RGS6,CTH,HDAC9,KIAA0586,SPOCK2,CHRDL1,DTNB,RASA4,EXTL2,MRVI1,ACSL4,IP6K2,CAMKK2,MPP6,LPAR4,PSIP1,KIF5A,MATK,MEF2C,NELL2,NFYA,PCDH18,KHDRBS2,FBXW7,SATB1,ARX,SLA,BTBD3,SOX15,SPTAN1,LMO3,MPRIP,TTBK2,STAC2,SYNE1,GPR161,JMJD1C,SOCS4" Transcription Factor Binding Site V$PAX4_02 V$PAX4_02 2.04E-04 1.25E-01 3.57E-03 2.50E-02 49 200 "PITPNM2,ARRB1,SLC4A4,ATP2A2,ATP6V0A1,DOCK11,C5,CA4,CAST,LDB2,CBFA2T2,CS,CSNK1E,ARHGAP24,ELMO1,CHRDL1,DLX1,WDPCP,MBNL2,NCALD,ETV1,EYA1,AGAP3,MPP6,NTNG2,STMN2,HAS2,ITGA7,ADAM11,MEIS2,MITF,NFIX,NNAT,OGG1,PAX6,SEMA5B,PCDH18,PDZRN4,PTPRG,RFX3,BTBD3,CPEB4,POGZ,TCF4,HIF3A,TRPS1,ZIC1,SLC38A1,PRDM8" Transcription Factor Binding Site V$PAX2_02 V$PAX2_02 2.25E-04 1.38E-01 3.74E-03 2.62E-02 50 206 "ADCY8,CADPS,CACNA2D2,CFL2,AKAP7,PHACTR3,KIAA0586,KLHL3,DMD,NYAP1,EGFR,GOLGA7,EIF4G1,EIF5,EPHB1,PTK2B,IP6K2,EVL,FLNC,MPP6,STARD3,STMN2,IGF1,LRRTM1,LSAMP,PACRG,MEIS2,MN1,NFYA,NTRK2,PFKFB3,SERPINI1,PLEC,PMP22,ING3,PPP2R2B,PPP3CA,PTH1R,RTN1,SEMA6D,ATF7IP,LMO3,TCF4,TRIM2,TCF12,ZFPM2,CHST8,XPO1,ZNF184,DPF3" Transcription Factor Binding Site V$E4BP4_01 V$E4BP4_01 2.30E-04 1.41E-01 3.74E-03 2.62E-02 44 175 "ADRB2,OSBPL6,OGT,CALM1,USP2,DGKI,LARGE1,NDST3,RGS6,CSNK1E,SPATA2,DMD,ECM2,CALCRL,EPB41,ACSL4,FGF14,FOXO3,FUT9,MPP6,GABARAPL2,NEGR1,IL6ST,MAP4,LRP1B,MPP2,NPTX1,PIK3R1,ZDHHC14,FBXW7,PREX2,EPN2,FAIM2,FNBP1,POGZ,RGL1,PLCB1,CLASP1,TNS2,UCHL1,ZBTB14,PRDM8,JMJD1C,JPH3" Transcription Factor Binding Site V$FOXO1_01 V$FOXO1_01 2.32E-04 1.42E-01 3.74E-03 2.62E-02 49 201 "AXIN2,C1QTNF3,BIN1,SEMA4G,CADPS,LINC00173,SPAG9,CBFA2T2,AP4M1,FOXN3,CREM,SNCAIP,CSNK1G3,PHACTR3,SLITRK5,DLX1,DMD,USP3,EPHB1,ETV1,EZH1,FGF12,FGF14,NIM1K,KCNN1,SMAD1,MITF,NF1,NFIX,NFYA,NTRK3,PALM,PLCB2,SDK2,RASGEF1B,PTPRD,SEMA6D,SH3GL3,ABLIM3,PREX2,ATF7IP,KDM3A,NMNAT2,LMO3,ANKRD28,THRA,NR2C2,TSC1,UBE2H" Transcription Factor Binding Site YTATTTTNR_V$MEF2_02 YTATTTTNR_V$MEF2_02 2.47E-04 1.51E-01 3.78E-03 2.65E-02 113 558 "NDRG3,SEMA6A,LRCH2,CASK,ARNTL,ADAM23,ADGRB3,NRP2,BMP7,JAZF1,CAPN3,CAST,USP2,DGKI,CHN1,RAB33A,NRXN3,SMARCAL1,SIPA1L1,PPP1R16B,RIMS2,HDAC9,HDAC4,MAML1,DGKB,C2CD2L,DMD,DMPK,DTNB,EDN1,HIPK3,MBNL2,ETV1,TLR7,EYA1,FGF12,FGF13,IP6K2,SEMA4D,NBEA,ATP2C1,PPARGC1A,NTNG2,MSL3,KCNMB4,GNAO1,GPER1,GPR34,PLCD4,GRIN2D,GRM8,LINC01089,MAP4K5,HAS2,HNF4G,HSF2,ZIC5,IL6R,ITGA7,KCNN1,KCNN3,KTN1,LAMA2,LIFR,MARK1,ADAM11,PPM1L,MITF,MXI1,MYO9A,NDP,NFIX,DPY19L2P2,PCDH9,PCSK1,ENPP2,PGAM2,RETREG1,FXYD1,PDZRN4,PPARA,PPM1B,RASGRF1,RFX3,PPM1E,FBXO11,EPN2,SLC14A1,SNAP25,KIF13A,FNBP1,SP4,ARHGAP26,SPTB,LMO3,RGL1,ADHFE1,ANKRD28,AGTPBP1,CLASP1,SYNE1,PCDHA6,SIK3,ZFPM2,KAT6B,TSC1,P2RY12,SLC30A4,HRASLS,DOCK8,JMJD1C,FXR1,RNF146" Transcription Factor Binding Site V$ER_Q6_01 V$ER_Q6_01 2.47E-04 1.51E-01 3.78E-03 2.65E-02 51 212 "NDRG2,KIAA1324,PHF12,PKP4,GAS7,DDR1,NOG,MAGED1,RIMS4,GREB1,SPOCK2,CHRDL1,HS3ST2,NYAP1,DTNB,ERBB4,MRVI1,FGF13,CAMKK2,GALNT15,GRM8,GABARAPL2,SHISA6,KCNN3,STMN1,LIFR,MID1,MITF,PCDH8,PPARA,LRRN3,CEP41,PTH1R,FIGN,ZNF532,FBXW7,SATB1,PPM1E,BTBD3,SPATA7,SPTAN1,PHLDB1,SIK3,TRPS1,TBC1D15,ZIC1,ZNF32,PRDM10,GAL3ST3,PCBP4,RTN4" Transcription Factor Binding Site V$OCT1_02 V$OCT1_02 2.94E-04 1.80E-01 4.39E-03 3.07E-02 45 182 "DOC2A,NRXN3,COL9A1,GAL3ST1,ZNF521,HDAC9,CHRDL1,DLX1,DMD,DNAH9,DPYSL2,TENM1,ERBB4,FGF13,FGFR1,GABRG2,PPARGC1A,GNAL,ZHX1,GABARAPL2,INSM1,KCNN3,MAP2,MBNL1,MEIS1,NPTX2,PAX6,PDE4D,PDZRN4,LRRN3,RASGEF1B,CEP41,PTPRN,CARF,PKNOX2,SEPHS1,ATF7IP,RGL1,TCF4,THRA,TRPS1,TSC1,ZIC1,ZIC2,PRDM8" Transcription Factor Binding Site V$E2A_Q2 V$E2A_Q2 3.17E-04 1.94E-01 4.62E-03 3.23E-02 47 193 "SPOP,AMPD2,APBB2,ATP2A2,ADGRB2,BCL7A,JAZF1,KALRN,CAMK2G,CAST,CBLN1,USP2,ARHGEF2,SLIT2,NRG2,PHACTR3,PABPC5,ARMCX2,WDR20,DMD,EIF4G2,FGF11,TPPP3,PSIP1,GUCY1B1,IGF1,MID1,PLCB2,PPP2R2B,MASP1,PSD,ANKHD1,ZNF532,CPEB3,EPN2,LGI3,NKAIN2,SEPT3,VPS13A,KCNE5,EIF4ENIF1,USP32P2,MKRN3,SH3GLB2,SLC30A3,PRDM8,NETO2" Transcription Factor Binding Site TGAYRTCA_V$ATF3_Q6 TGAYRTCA_V$ATF3_Q6 3.40E-04 2.08E-01 4.84E-03 3.39E-02 90 430 "ABR,ADCY8,ADRA1B,AP2A2,PKP4,PRX,CDK13,CACNA1G,CA12,CALM1,CH25H,SPAG9,KYAT1,CBFA2T2,SYNGR3,CFL2,CHGB,SULT4A1,CNN3,CREM,AKAP12,HAPLN1,RNF14,CS,SNCAIP,PHACTR3,KCTD8,DAPK3,SPOCK2,PITPNC1,DCTN1,PARD6A,HS3ST2,RCAN1,CELSR3,EGFR,MBNL2,PLEKHA1,ING4,EPB41,RCAN2,NCALD,DNAJC27,EYA1,OLFM1,FGF12,ZMYND15,FLT1,AKAP3,ABLIM2,PPARGC1A,RUNDC3A,RAB30,LOXL3,ADAP1,ELOVL5,IGF1,KCNF1,KCNN2,ZFYVE27,ADAM11,SCAMP5,MID1,MITF,MYO7A,MYT1,NF1,NOVA2,PCSK1,PNMA3,SCHIP1,MAPK10,FIGN,SBF1,TNFRSF19,SH3BGR,SNAP25,FAIM2,SPATA7,LMO3,SST,ST5,FBXW11,TBL1X,NR2E1,RUSC1,UBE2H,VGF,ZNF184,SLC38A1" Transcription Factor Binding Site V$HOXA4_Q2 V$HOXA4_Q2 3.99E-04 2.44E-01 5.32E-03 3.72E-02 51 216 "BBOX1,ALK,DPP10,BMPR1B,ARHGEF7,SPAG9,ARHGEF2,CNN3,CS,CYBB,BOC,HDAC4,DLX1,DMD,SHANK1,WDPCP,PHC2,MBNL2,EIF4G2,RCAN2,SYNCRIP,GCK,PPARGC1A,ZHX1,GABARAPL2,LRRTM1,MAP2,MEF2C,MITF,NTRK2,ZNF827,PCDH9,PIK3R1,PDZRN4,PPM1E,KDM4D,SLC9A5,ELMO2,CPEB4,LMO3,POGZ,ST5,STAC2,SYNE2,ADAMTS17,NSD1,DICER1,CHST8,THRA,ZIC1,GAL3ST3" Transcription Factor Binding Site GGGTGGRR_V$PAX4_03 GGGTGGRR_V$PAX4_03 4.02E-04 2.46E-01 5.32E-03 3.72E-02 197 1068 "ABR,ASIC1,NDRG2,ADD1,ADORA2A,MTUS1,SEMA6A,SPOP,BEGAIN,ANK2,SEMA7A,MAP4K3,CPNE5,IGDCC4,SPTBN4,CHRD,RASL11B,ATP1A3,DOCK11,ADGRB2,LDHD,BMP7,BTK,AP1M1,CACNA1G,GPC2,CACNA1A,CAST,SPAG9,KYAT1,USP2,ARHGEF1,CD38,ARHGEF2,CRLF1,NUMBL,FOXN3,CPNE6,COL9A1,COL11A2,MAGED1,ZNF521,NRG2,ZNF385A,HAPLN1,CS,PHACTR3,DZIP3,ARHGAP32,RASSF2,KIAA0586,PITPNC1,DCTN1,C2CD2L,CHRDL1,DLX1,DMPK,HS3ST2,NYAP1,SLC12A6,DPYSL2,EGR3,EIF4G1,EIF4G2,CERCAM,ELN,DCTN4,ENO2,RASGRP2,EPHB1,NCALD,HSPA12B,CLVS1,PTK2B,FGF11,FGFR1,FHL1,MEX3B,HPCAL4,SYNCRIP,FLNC,FLT1,FOLR2,TPPP3,OGA,FYN,GABRG2,IQGAP2,ARFIP1,SESN1,RUNDC3A,RAB30,GNAO1,FERMT2,STMN2,PLCD4,GRIN2D,AP4S1,ATOH8,BACH2,AGBL5,NEGR1,IGF1,ZIC5,ITPKB,KCNH2,KCNN3,MAP4,MAPT,MBNL1,ADAM11,MEIS2,MGAT3,SCAMP5,MN1,MOV10,MPP2,MSI1,HS6ST3,MXI1,FXYD7,NBL1,NCAM2,NFIX,CNOT4,OPRL1,ZNF827,PAX6,GPR85,ZDHHC8,NLGN3,SERPINI1,PLEC,PURG,PMP22,TRHDE,STRN3,PPM1B,PPP2R2B,PKIA,MAPK3,PRPH,PSD,GDPD2,PTPRN,ZCWPW1,ZDHHC14,CRTAC1,LGI2,ZNF532,ELP2,EMID1,SALL1,LRFN5,SCN8A,ZNF821,MYO18A,FAM214B,SLC6A11,RADIL,SLC9A5,SLC12A4,EPC1,TRERF1,SOX15,KDM3A,SP2,SP4,ARHGAP26,SPTAN1,SPTB,POGZ,SEPT3,PJA1,TAL1,TCF4,CLASP1,ZFPM2,THRA,HEY1,TP53BP1,EIF4ENIF1,UBE3A,WRN,KCNK12,LGI4,ZIC2,CELF4,DPYSL5,SH3GLB2,PRDM10,ADAMTS9,SEMA3B,PCBP4,RTN4,FBXO36,JMJD1C" Transcription Factor Binding Site V$CHX10_01 V$CHX10_01 4.07E-04 2.49E-01 5.32E-03 3.72E-02 47 195 "ASIC1,MTUS1,OGT,CASK,BACH1,LDB2,CNN3,CS,DLX1,DMD,RCAN1,WDPCP,ETV1,PPP1R1B,FOXF2,AGAP3,FYN,MSTN,GNAO1,LPAR4,LRRTM1,CDH20,MAP4,MITF,PAX6,PCDH9,SEMA5B,PCDH18,PDZRN4,PTPRG,FIGN,RGS12,LRFN5,PPM1E,BTBD3,ELMO2,ZNF423,LMO3,POGZ,SYNE2,ADAMTS17,CHST8,THRA,KAT6B,VLDLR,VSNL1,ZIC1" Transcription Factor Binding Site TAATTA_V$CHX10_01 TAATTA_V$CHX10_01 4.08E-04 2.50E-01 5.32E-03 3.72E-02 129 659 "NCKAP5,MTUS1,OSBPL8,ALK,PITPNM2,OGT,DPP10,SEMA7A,SEMA4G,CASK,ARNTL,ARRB1,RASL11B,ATP2A2,BACH1,BMPR1B,ARHGEF7,C5,GPC2,CA4,LDB2,ARHGEF2,CDO1,FOXN3,CNN3,WHRN,COL4A5,COL11A2,HAPLN1,CS,SOCS5,SLITRK5,PITPNC1,ELMO1,DLX1,DMD,RCAN1,WDPCP,EMX2,ERBB4,ETV1,EYA1,DLC1,PPP1R1B,FOXF2,AGAP3,ZBED3,FYN,CHL1,MSTN,NTNG2,GNAO1,LPAR4,STMN2,ADAMTS13,GRM8,BACH2,IFI16,NIM1K,LRRTM1,CDH20,KCNN3,LIMS1,SMAD1,MBNL1,ADAM11,MEF2C,MID1,MITF,MYT1,NDP,NELL2,NFIX,NFYA,NOVA1,OGG1,PAX6,SEMA5B,KCTD15,PCDH18,PDZRN4,PPP2R2B,CEP41,PTH1R,PTPRO,FIGN,RFX3,RGS12,ROBO1,RORB,ELP2,SALL1,LRFN5,PPM1E,BTBD3,SLC9A5,ELMO2,CPEB4,CMTR2,UNC5B,ZNF423,ARHGAP26,LMO3,CLSTN2,POGZ,STAC2,SULF2,SYNE2,ADAMTS17,ARC,PJA1,TAL1,KLHL4,PCDHB15,PCDHB3,PCDHA6,CHST8,ITGB3BP,THRA,KAT6B,TP53BP1,VLDLR,WNT7A,ZIC1,PRDM8,FIP1L1,PHTF2,ADAMTS10,JPH3" Transcription Factor Binding Site V$OCT1_03 V$OCT1_03 4.32E-04 2.65E-01 5.51E-03 3.86E-02 45 185 "PHF12,ATP6V0A1,NRP2,ARHGEF7,FOXN3,MS4A7,COL4A5,RIMS2,HDAC9,DLX1,DMD,RCAN1,WDPCP,EMX2,RCAN2,PIPOX,EYA1,CLVS1,DLC1,FGF13,FOXO3,BACH2,LIFR,MBNL1,MEF2C,MEIS2,MID1,MITF,NFIX,NPTX2,PLEC,PPP2R2B,PTPRG,FBXW7,SALL1,FRMPD1,FBXO11,SLC6A11,ZNF423,LMO3,TBL1X,TCF4,CDH22,TP53BP1,JPH3" Transcription Factor Binding Site V$E12_Q6 V$E12_Q6 4.44E-04 2.72E-01 5.55E-03 3.88E-02 48 201 "MTUS1,KLHL13,SORCS2,DOC2A,ANK2,CALB1,KALRN,CAMK2A,USP2,CDH2,RAB26,PHACTR3,ARHGAP24,RASSF2,ELMO1,WDR20,CHRDL1,DMPK,HEYL,PTK2B,CORO2B,FGF11,PRKAG2,AGAP3,DLL3,FYN,GPD1,GPR37,NEGR1,MYLK2,KCNB1,KCNN3,GIT1,NBL1,NTRK2,NTRK3,PLEC,PPARA,CNNM2,GDPD2,HES6,ABLIM3,TTC17,SPTB,NKAIN2,HIF3A,KCNK12,CELF4" Transcription Factor Binding Site V$OCT1_07 V$OCT1_07 4.56E-04 2.79E-01 5.58E-03 3.90E-02 34 129 "ADORA2A,MTUS1,MAGEE2,ZBTB10,JAZF1,LDB2,RAB26,HDAC9,SCRN1,HEPH,RCAN1,ETV1,CLVS1,FGF11,KCNN3,MBP,MID1,MYT1,NDP,NFIX,GPR85,TMOD2,SEMA5B,PDZRN4,SALL1,LRFN5,SLA,BTBD3,CPEB4,TRERF1,SOX3,PLCB1,UBE3A,ZIC1" Transcription Factor Binding Site TTANTCA_UNKNOWN TTANTCA_UNKNOWN 5.84E-04 3.57E-01 6.76E-03 4.73E-02 145 760 "METAP1D,ADCY8,KLHL13,ALK,TRMT9B,CPNE5,CASK,ASPA,NRP2,JAZF1,C5,WASF1,CA8,CABP7,HIP1R,SPAG9,USP2,CBFA2T2,DGKI,DCLK1,LARGE1,MAGI1,NOG,CRLF1,NUMBL,CHN2,CLTC,HOMER3,FHL5,COL4A5,CREM,CRHBP,ARHGAP24,TBC1D5,DBN1,PITPNC1,DLX1,EXOG,DMD,DNM1,USP3,RCAN1,EDN1,NCALD,EYA1,ACSL4,DLC1,FGF12,FGFR1,BAIAP2,IP6K2,AGAP3,FLT1,UFM1,CHL1,GAD1,RAPGEF6,GCNT2,MSTN,CYP46A1,GPD1,GPR34,STMN2,ADAMTS6,SYNPO,HNMT,SHISA6,IGF1,ZIC5,CDH20,KIF5A,L1CAM,LIFR,LMO2,SMAD1,MAP2,ADAM11,MEIS2,KITLG,PPM1L,MITF,NDP,NFIX,NPTX2,PAX6,PCDH9,PCSK1,PDE4D,SEMA5B,TMIE,KCTD15,PLCB2,PMP22,POLG,PPP2R2B,RASGEF1B,PKIA,MAPK9,MASP1,PTPRG,PTPRO,ZCWPW1,CRTAC1,PRIMA1,LGI2,ZNF532,RORB,FBXW7,RTN1,SALL1,CPEB3,FBXO11,NLGN1,SLC8A1,SLC9A5,CPEB4,TRERF1,ZNF423,SPTB,LMO3,MESP1,SSTR1,ERBIN,ST5,RGL1,STAC2,SULF2,ANKRD28,PJA1,TAF6,PCDHB3,ZFPM2,NR2E1,TRPS1,TSC1,UBE3A,VLDLR,ZIC2,SLC30A3,PRDM8,GAL3ST3,HRASLS,JMJD1C,DPF3,CPNE4" Transcription Factor Binding Site V$ZF5_B V$ZF5_B 5.84E-04 3.58E-01 6.76E-03 4.73E-02 47 198 "ASIC1,SEMA6A,BCL7A,MTMR3,KCNAB3,LHX2,COL11A2,NRG2,CLOCK,SV2B,GRIN3A,NYAP1,CDON,RASGRP1,PLXNC1,GPHN,FGF12,FGF13,FGFR3,SYNCRIP,GABRA3,MTHFD2,HTATSF1,ZDHHC15,INSM1,STMN1,MAT2A,MEIS2,CLDN11,ZNF827,PCDHGC3,NLGN3,EPB41L4B,PPP3CA,PSD,PTPRG,CRTAC1,RPS6KA2,TRA2B,SCAF8,ABLIM3,LGI3,EPC1,PLCB1,THRA,NR2E1,ZIC2" Transcription Factor Binding Site V$CDC5_01 V$CDC5_01 5.85E-04 3.58E-01 6.76E-03 4.73E-02 50 214 "ARNTL,ADGRB3,NRXN3,CSNK1G3,MAML1,DGKB,CHRDL1,TENM1,EYA1,ACSL4,FGF12,FYN,PPARGC1A,ADAMTS6,BACH2,ITPKB,MBNL1,MN1,MXI1,NOVA1,NPTX1,ZNF827,PCDHGC3,PCDH8,ENPP2,GPR85,PIK3R1,KCTD15,PDZRN4,ING3,PPP2R2B,PRKACB,RORB,SALL1,LRFN5,SCN7A,BTBD3,CPEB4,FNBP1,LMO3,SAMSN1,KLHL4,CLASP1,TNS2,ZFPM2,TRPS1,UCHL1,KCNK12,NDRG4,ADAMTS9" Transcription Factor Binding Site V$OCT_Q6 V$OCT_Q6 6.29E-04 3.85E-01 7.13E-03 4.99E-02 51 220 "ADORA1,ADORA2A,MTUS1,ALK,ATP2A2,BTK,LDB2,CD86,CBFA2T2,NRXN3,RAB26,PCYT1B,RTTN,HDAC9,DAPK3,DLX1,DMD,DPYSL2,RCAN1,SUGP2,ETV1,EYA1,FGF12,FGF14,HPCAL4,KCNN3,MID1,NDP,PAX6,PCDH8,PDE4D,GPR85,TMOD2,PPP2R2B,CEP41,MRAS,SH3GL3,ATF7IP,CXXC4,KIF13A,TRERF1,ZNF423,LMO3,TCF12,THRA,TSC1,MGAT5B,PLPPR2,VSNL1,FSTL5,PRDM10" Transcription Factor Binding Site V$NRSF_01 V$NRSF_01 7.02E-04 4.30E-01 7.81E-03 5.47E-02 23 78 "KCNH8,FGD2,ATP2B2,ATP6V0A1,CALB1,BRINP1,FGF12,GABRB3,GABRG2,RUNDC3A,STMN2,L1CAM,SCAMP5,NEFH,PTPRN,RASGRF1,OGDHL,SNAP25,SST,SLC35G2,MGAT5B,VGF,TRIM9" Transcription Factor Binding Site TGACAGNY_V$MEIS1_01 TGACAGNY_V$MEIS1_01 7.55E-04 4.62E-01 8.25E-03 5.77E-02 125 645 "ADCY5,ADCY8,FZD9,ADRA1B,CASKIN1,AK2,SPARCL1,PCDH10,UNC79,CDC42BPA,DPP10,PHF12,CASK,LINC00173,ATP1A3,ADGRB3,MTMR3,SLC25A14,CAST,SPAG9,USP2,ARHGAP33,CHN2,CLTC,MAP4K4,TBPL1,NRG2,CDC42BPB,RNF14,RGS6,DOCK4,KCTD8,SPOCK2,ELMO1,RHOBTB1,WDR20,DMD,DMTF1,PHC2,GPHN,NCALD,ETV1,EXTL2,EYA1,PTK2B,PPP1R1B,FGF12,FGF13,FOXO3,NOP56,CAMKK2,ATP2C1,GALNT15,GAD1,IP6K3,GATM,SESN1,PCDH17,PPARGC1A,GNAO1,GRB10,AP4S1,BACH2,ELOVL5,MYLK2,KCNH2,LMO2,LSAMP,PACRG,MAP2,MBNL1,MEIS1,MEIS2,KITLG,MITF,MN1,MYT1,NNAT,CNOT4,PAX6,PCDHGC3,ENPP2,PFKFB3,TMIE,PLCB2,PDZRN4,STRN3,SDK2,PPP2R2B,PPP3CA,PTN,RFX3,PBRM1,HUNK,FAM192A,SEMA6D,HES6,TNFRSF19,ZNF821,SLC12A2,ELMO2,TRERF1,KDM4C,SPTB,CLSTN2,TACC1,ANKRD12,TNS2,SIRT1,TIAM1,NR2E1,TPM2,EIF4ENIF1,UBE2H,UBE3A,PLPPR2,VLDLR,XPO1,SLC30A4,MDH1B,NAV3,PCBP4,KAT6A,FXR1,DPF3" Transcription Factor Binding Site RNGTGGGC_UNKNOWN RNGTGGGC_UNKNOWN 7.76E-04 4.75E-01 8.33E-03 5.83E-02 118 604 "FMNL2,AK2,BEGAIN,AMPD2,PHF12,PKP4,PPFIA3,USP37,PRX,SYNJ1,CACNA1A,PTBP2,CAMK2A,HIP1R,CERS5,P2RX6,CD86,SYNGR3,LRRFIP1,COL9A3,NRG2,AKAP12,SOCS5,RIMS4,PPP1R16B,ARMCX2,DCTN1,PARD6A,DMD,DMPK,SHANK1,DMTF1,DPYSL2,EGR3,RGS17,EMX2,EPHB1,ACSL4,PTK2B,DLC1,FGF11,FGF12,POLK,SYNCRIP,FLT1,FYN,GABBR1,CHL1,STMN2,ADAMTS13,KAT7,NXPH3,ELOVL5,DHX35,SHISA6,ITPKB,KCNB1,KCND1,KCNH2,KCNN3,MAN2A2,CHST6,MEIS2,MPP2,GIT1,MXI1,NRCAM,OGG1,PFKFB3,PKD1,KCTD15,SH3KBP1,PPP2R2B,PPP2R2C,CEP41,PRKCB,KLK6,ANKHD1,PTPRE,ZCWPW1,RBBP6,CYB561D1,FBXW7,FAM192A,SAFB,SALL1,SH3GL3,PPM1E,BTBD3,FAM214B,KANSL3,CMTR2,TRERF1,SP4,SPTAN1,SSTR1,ST5,TTBK2,COBL,PDLIM2,KLHL4,SATB2,TNS2,SIK3,NR2E1,TP53BP1,RUNDC3B,CA14,HIRA,VLDLR,CELF4,SH3GLB2,ADAMTS9,SEMA3B,PCBP4,FBXO36,AP3B2,CPNE4" Transcription Factor Binding Site YATTNATC_UNKNOWN YATTNATC_UNKNOWN 8.27E-04 5.06E-01 8.73E-03 6.11E-02 66 305 "AXIN2,C1QTNF3,ANK2,PKP4,LINC00173,RASL11B,ATP2A2,BMPR1B,CA4,CALB1,ARHGAP33,CFL2,FOXN3,RAB33A,QKI,HAPLN1,SLITRK5,DOCK4,KCTD8,PITPNC1,ELMO1,DMD,MBNL2,EGR3,EMX2,EYA1,DLC1,FOLR2,ABLIM2,GABRB3,GNAO1,STMN2,ADAMTS6,HNMT,USP51,SHISA6,IGF1,NKD1,LRRTM1,KCNH2,KIF5A,MITF,MN1,MXI1,NDP,NFIX,NOVA1,NPTX2,PCSK5,NALCN,TMIE,PLEC,PDZRN4,PPP2R2B,RASGEF1B,ABLIM3,CPEB4,TRERF1,SP4,SSTR1,SYT1,NSD1,ZIC1,ZIC2,CELF4,ST7" Transcription Factor Binding Site V$RSRFC4_01 V$RSRFC4_01 9.94E-04 6.08E-01 1.03E-02 7.17E-02 48 208 "NDRG2,ADAM23,ADGRB3,CAPN3,USP2,DGKI,CFL2,NRXN3,CNTN1,HAPLN1,SIPA1L1,HDAC9,ARHGAP32,ELMO1,DMD,SHANK1,DTNB,MBNL2,EYA1,FGF12,GCK,HAS2,ITGA7,KCNN1,KTN1,TTYH2,ADAM11,MEF2C,MYH3,NDP,PCDH9,RETREG1,RASGEF1B,PTPRO,RASGRF1,RGS3,SLC9A5,CPEB4,ARHGAP26,FBXW11,SIK3,ZFPM2,ITGB3BP,TRPS1,CELF4,SH3GLB2,GAL3ST3,HRASLS" Transcription Factor Binding Site V$SOX9_B1 V$SOX9_B1 1.01E-03 6.15E-01 1.03E-02 7.17E-02 45 192 "ADRB2,KLHL13,CASK,TMEFF1,CADPS,CBFA2T2,SLIT2,MAP4K4,SEC24C,PPP1R16B,PUM1,DOCK4,HDAC9,MAML1,RHOBTB1,DLX1,DMD,CDON,DPYSL2,ETV1,DLC1,OLFM1,FGFR1,CHL1,GNAO1,KCNN2,MBP,MEIS1,MYT1,NDP,NFIX,PPP2R2B,RGS3,MYO18A,SEPHS1,TAL1,TEK,UBE3A,VLDLR,ZIC1,ZIC2,DPYSL5,RTN4,KAT6A,GJC2" Transcription Factor Binding Site V$RP58_01 V$RP58_01 1.04E-03 6.39E-01 1.05E-02 7.33E-02 44 187 "ABR,ASIC1,C1QTNF1,ANK2,GAS7,PTCH2,ATP2A2,ADGRB3,CACNA1G,CABP7,CALM1,ARHGAP22,MAGED1,TBPL1,RIMS2,DAPK1,DMD,MBNL2,TLR7,EYA1,GRIN2D,ATOH8,NXPH3,IGF1,PACRG,NTRK2,GPSM2,PPM1B,SEMA6D,SCN2B,KIF21A,ARX,ABLIM3,BTBD3,DHX30,SPTB,LMO3,PHLDB1,SEPT3,ANKRD12,TCF12,UBTF,SH3GLB2,ADAMTS10" Transcription Factor Binding Site V$POU6F1_01 V$POU6F1_01 1.26E-03 7.71E-01 1.24E-02 8.70E-02 45 194 "BEGAIN,C5,HIP1R,SPAG9,CBLN1,CFL2,FOXN3,FHL5,RHOBTB1,DLX1,TENM1,EMX2,ETV1,EYA1,FGF13,MPP6,ABLIM2,FYN,PPARGC1A,NTNG2,GRIK4,CDH20,MBNL1,ADAM11,MEIS1,MEIS2,PPM1L,MYT1,NDP,ZNF827,TMIE,KCTD15,PCDH18,PDZRN4,PTH1R,RFX3,PRIMA1,FBXW7,SEPHS1,LMO3,SYT5,NSD1,PCDHA3,ZFPM2,RTN4" Transcription Factor Binding Site V$AP2_Q6_01 V$AP2_Q6_01 1.44E-03 8.80E-01 1.40E-02 9.77E-02 47 206 "KCNH8,UNC79,APLP1,KCNAB3,LHX2,DBN1,DMPK,NYAP1,DTNB,EGR3,PLXNC1,EIF4G2,CERCAM,RASGRP2,EPHB1,EYA1,FGF11,ATP5PD,CGREF1,OGA,MSTN,GP1BB,GPR12,CLASRP,NXPH3,ITPKA,KCNH2,KCNK3,STMN1,MN1,PFKFB3,FXYD1,RAP1GDS1,CYB561D1,SALL1,LRFN5,PPM1E,CPEB3,SLC6A11,SLC12A4,FNBP1,CAMTA2,HEY1,NR2E1,UBTF,SLC17A7,ST7" Transcription Factor Binding Site V$OCT1_Q6 V$OCT1_Q6 1.53E-03 9.34E-01 1.44E-02 1.01E-01 48 212 "ADORA1,ADORA2A,MTUS1,ATP2A2,NRP2,PROM1,BTK,LDB2,CBFA2T2,RAB26,PCYT1B,COL11A2,RTTN,SOCS5,RIMS2,DLX1,DMD,SUGP2,ETV1,DLC1,FGF14,KCNN3,MAP2,MID1,NDP,PAX6,PCDH8,PDE4D,GPR85,TMOD2,PRKCB,RGS3,MRAS,SH3GL3,CXXC4,TRERF1,LMO3,STAC2,TCF4,SATB2,THRA,NR2C2,TSC1,PLPPR2,VSNL1,PCDH20,PRDM10,DPF3" Transcription Factor Binding Site V$NKX3A_01 V$NKX3A_01 1.53E-03 9.37E-01 1.44E-02 1.01E-01 43 185 "NCKAP5,ATP2A2,NOG,NRXN3,ZNF521,SLITRK5,DMD,EYA1,DLC1,GPR12,GRM8,ZIC5,LRRTM1,KCNN3,KIT,MBNL1,ADAM11,MID1,MYT1,NNAT,PAX6,GPR85,PDZRN4,SH3KBP1,PTH1R,PTN,SALL1,LRFN5,CASC3,ARX,DHX30,KDM4D,CMTR2,ZNF423,SPTB,LMO3,ADAMTS17,TCF12,ZFPM2,THRA,TPM1,WNT7A,ZIC1" Transcription Factor Binding Site V$AR_01 V$AR_01 1.56E-03 9.56E-01 1.45E-02 1.01E-01 29 112 "AMPH,CLDN10,USP2,BRINP1,DTNB,CALCRL,OLFM1,IP6K2,SDCBP2,IP6K3,ITGA7,ITPKB,JAK2,KCNH2,LIFR,SMOX,FXYD1,PMP22,PSMA6,ZNF532,SGK1,SLC9A5,LGI3,SNAP25,KIF13A,TRERF1,TP53BP1,VGF,WNT7A" Transcription Factor Binding Site V$AP2_Q3 V$AP2_Q3 1.60E-03 9.78E-01 1.46E-02 1.02E-01 47 207 "SPOP,GAS7,APLP1,ADAM23,CACNA1G,CHN2,LHX2,HECTD1,COL11A2,ZNF385A,CLOCK,C1QL2,PHACTR3,SLITRK5,PITPNC1,CNNM1,PLXNC1,EIF4G2,EMX2,EPHB1,MEX3B,FOXO3,OGA,KAT7,KCND1,KCNN2,MAPT,MAT2A,MOV10,MSI1,MYCN,NLGN3,RAP1GDS1,CRTAC1,PBRM1,SALL1,PPM1E,SLC4A3,SLC12A4,EPC1,CAMTA2,HEY1,HIRA,UBTF,ZIC1,ZNF70,SLC30A3" Transcription Factor Binding Site V$ZIC3_01 V$ZIC3_01 1.69E-03 1.00E+00 1.52E-02 1.07E-01 48 213 "MTUS1,PCDH10,OGT,PHF12,PRX,PTCH2,STX16,ARHGAP33,CLTC,CNTFR,ZNF521,PPP1R16B,EPHB1,SYNCRIP,GABRA3,GABRG2,GHR,LOXL3,GNAO1,GRIN2D,HAS2,NEGR1,KCND2,KCNH2,KCNK3,MYCN,NELL2,PAX6,GPR85,NLGN3,MAPK10,GDPD2,ZNF532,CYB561D1,SAFB,DHX30,TRERF1,ZSWIM8,TAL1,THRA,TIMP4,CA14,UCHL1,CRB2,PRDM8,PRDM10,SEMA3B,PCBP4" Transcription Factor Binding Site TGCTGAY_UNKNOWN TGCTGAY_UNKNOWN 1.74E-03 1.00E+00 1.53E-02 1.07E-01 88 440 "ASIC1,GALNT13,AXIN2,SPOP,PCDH10,PKP4,PRX,MADD,ASPA,ADGRB2,NRP2,CACNA1B,CAMK2A,USP2,P2RX6,NUMBL,HECTD1,NECTIN3,PPP1R16B,ARHGAP24,SPOCK2,PABPC5,PITPNC1,ARMCX2,SHANK1,DRP2,DTNB,ETV1,F5,DLC1,FGF13,MEX3B,SYNCRIP,AGAP3,FYN,GABBR1,SRCAP,ARFIP1,LYVE1,NTNG2,RAB30,KCND1,MAP4,MEIS1,MEIS2,MITF,PTOV1,MXI1,PCDHGC3,PCSK1,CDK18,PDE1C,ENPP2,GPR85,PFKFB3,SNX10,PLEC,PCDH18,PURG,PDZRN4,PPP2R2B,GDPD2,PTPRG,PTPRN,ZNF532,FBXW7,MAPK12,GALNT10,PPM1E,FBXO11,SNAP25,MBD5,LMO3,ANKRD28,SYT5,TBL1X,TCF4,TRIM2,SZT2,NSD1,TEK,DICER1,ZFPM2,WNT7A,WRN,KCNK12,PCBP4,JMJD1C" Transcription Factor Binding Site V$BRN2_01 V$BRN2_01 1.75E-03 1.00E+00 1.53E-02 1.07E-01 45 197 "C5,NOG,CHN2,NDST3,NRXN3,CNN3,CLOCK,CS,RGS6,PPP1R16B,ELMO1,DLX1,DMD,EDNRA,MBNL2,TENM1,EXTL2,EYA1,PPP1R1B,FGF13,FGF14,FGFR3,IP6K2,GNAO1,STMN2,MBNL1,ADAM11,MMP16,MYT1,NCAM2,PLCB2,PLEC,PCDH18,PDZRN4,PPM1B,PTPRG,PTPRO,RPE,SALL1,SNAP25,SOX3,AGTPBP1,TCF4,ITGB3BP,NR2E1" Transcription Factor Binding Site V$AP4_Q6_01 V$AP4_Q6_01 1.78E-03 1.00E+00 1.53E-02 1.07E-01 47 208 "ABR,SPOP,ALK,GAS7,CADPS,CHRD,BACH1,ARHGEF2,NUMBL,ZNF385A,CSF1R,SPOCK2,BRINP1,DMD,DRP2,MBNL2,ETV1,RASL12,EYA1,CLVS1,FGF12,FGF13,TPPP3,GRIN2D,LINC01089,PSIP1,AGBL5,KCNN2,MYCN,MYH3,MYO7A,PPP3CA,PRKCB,MASP1,PSD,PTH1R,RGS12,HES6,FRMPD1,MYO18A,PREX2,BTBD3,ATF7IP,ZSWIM8,ADGRL3,EIF4ENIF1,PCBP4" Transcription Factor Binding Site V$CHOP_01 V$CHOP_01 1.83E-03 1.00E+00 1.56E-02 1.09E-01 44 192 "AP2A1,CASK,ZBTB10,CAST,CARS,ARHGEF6,CNTFR,SNCAIP,SOCS5,DPYSL2,PLXNC1,GPHN,FGF11,FGF14,SYNCRIP,TPPP3,PCDH17,PPARGC1A,KCNN2,STMN1,MAP4,MBNL1,TM6SF1,MEF2C,MEIS1,KITLG,NFE2L2,NTRK2,NTRK3,PCDH9,SEMA5B,KCTD15,PCDH18,PDZRN4,ZNF532,SARS,FBXO11,TRERF1,LMO3,ANKRD28,TBL1X,ITGB3BP,SH3GLB2,JMJD1C" Transcription Factor Binding Site GGGYGTGNY_UNKNOWN GGGYGTGNY_UNKNOWN 1.96E-03 1.00E+00 1.65E-02 1.15E-01 102 524 "KCNH8,ABR,ADCY8,SEMA6A,SRPX,OGT,MAP4K3,KCNAB2,MAGEE2,PRX,IGDCC4,ATP1A1,ATP1A3,BCS1L,MTMR3,GPC2,CACNA1B,KALRN,CAST,AP4M1,CRLF1,B4GALT6,CPNE6,CNTFR,COL9A1,COL11A2,NRG2,CRMP1,GDA,BOC,MYADM,IST1,SPOCK2,DBI,ARMCX2,WDR20,NYAP1,DPYSL2,EDIL3,PLXNC1,ARMCX1,PTK2B,SCML2,FHL1,VTI1B,DCTN2,ATP2C1,CELF1,GABRA3,CHL1,RAB30,LPAR4,MAP4K5,DHX35,KCND1,KCNH2,KCNK3,KIF5A,LAMP2,STMN1,PIK3AP1,MITF,MOV10,MPP2,PTOV1,NELL2,NFYA,NOVA2,NTRK2,PALM,PCDH9,PLEC,PMP22,MAGEL2,MBOAT7,EPB41L4B,SH3KBP1,CNNM2,PSD,RGS3,RTN1,SCN8A,FAM214B,NAPB,TRERF1,CAMTA2,STX1A,EXOC7,SYNE1,DOCK9,HIF3A,SIK3,THRA,KCNE5,UCHL1,BCL2L13,PLPPR2,XPO1,LGI4,DPYSL5,SEMA3B,PCBP4" Transcription Factor Binding Site WTGAAAT_UNKNOWN WTGAAAT_UNKNOWN 2.16E-03 1.00E+00 1.79E-02 1.25E-01 97 496 "NCKAP5,SPARCL1,PCDH10,OGT,PKP4,APC,ASPA,ZBTB10,MTMR3,JAZF1,C5,LDB2,USP2,DCLK1,RAB33A,CPS1,CREM,HAPLN1,SNCAIP,SLITRK5,HDAC9,SNPH,SPOCK2,RHOBTB1,DMD,RCAN1,ARRDC4,KLHL5,TENM1,TUBD1,NCALD,PIPOX,GMPR2,FGF11,FGF13,NBEA,FYN,MTHFD2,HTATSF1,GPD1,GPER1,STMN2,GRM8,PSIP1,SHISA6,IGF1,IL6ST,INPP1,STMN1,ADAM11,SHC3,MEF2C,MID1,MITF,MN1,GIT1,MYT1,NFE2L2,NPTX2,OCRL,OGG1,P2RY1,PAX6,PCDHGC3,PLCL1,PURG,PPM1B,PPP2R5E,PRKAB2,PTK2,PTPRD,RFX3,RGS12,ROBO1,RORB,FBXW7,SCN7A,SCN8A,TNFRSF19,ARX,BTBD3,SEPHS1,MBD5,TRERF1,SPATA7,ZNF423,SPTAN1,LMO3,ANKRD28,TCEA1,TCF4,NR2E1,EIF4ENIF1,P2RY12,ZIC1,NAV3,KAT6A" Transcription Factor Binding Site V$ZIC1_01 V$ZIC1_01 2.29E-03 1.00E+00 1.87E-02 1.31E-01 48 216 "FMNL2,MTUS1,PHF12,PTCH2,CBLN1,MAGED1,DCTN1,DMTF1,EIF4G1,CERCAM,ERBB4,ACSL4,FCGR3A,USP21,GABRG2,GHR,GNAO1,GRIN2D,NXPH3,USP51,NEGR1,SHISA6,KCND1,KCND2,KCNH2,MBNL1,GIT1,NELL2,NFYA,CDK18,NLGN3,PMP22,DEF8,CYB561D1,FAM192A,SALL1,CPEB3,DHX30,KANSL3,TRERF1,SZT2,PCDHGA2,TPM2,CA14,CRB2,PRDM10,SEMA3B,PCBP4" Transcription Factor Binding Site V$HSF1_01 V$HSF1_01 2.41E-03 1.00E+00 1.94E-02 1.36E-01 47 211 "ADCY6,ADCY8,SLC24A4,PCDH10,UNC79,LINC00173,CACNA2D2,PLEKHB1,NRXN3,PPT2,CREM,SOCS5,GREB1,RIMS2,DBI,DMD,SHANK1,ABCC5,MBNL2,EGR3,PLXNC1,EIF5,RASGRP2,FHL1,FLNC,GAD1,GSN,ELOVL5,SHISA6,SMAD1,MAP2,HS6ST3,NNAT,PURG,PPP2R2C,CARF,RORB,RTN1,TNFRSF19,TRERF1,ANKRD28,CHST8,TPM2,NR2C2,WRN,ADAMTS9,NETO2" Gene Family 555 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 1.48E-14 7.86E-12 5.15E-12 3.53E-11 49 160 "ELFN2,LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,BOC,CDON,FSD1L,EBI3,EPHB1,CHL1,GHR,PTPRT,IL6ST,L1CAM,LIFR,MID1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,ROBO1,ROBO2,EPHA10,LRFN5,FNDC3A,TRIM67,ATF7IP,ANKFN1,NFASC,ASTN2,TEK,FLRT2,TRIM9,ELFN1" Gene Family 593 Fibronectin type III domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 1.94E-14 1.03E-11 5.15E-12 3.53E-11 49 161 "UNC5A,LRFN2,ADGRF5,LRFN1,IGDCC4,MYOM1,KALRN,CNTN1,NRG2,IGDCC3,NECTIN3,LRIG1,BOC,MFAP3L,CDON,SPEG,FGFR1,FGFR3,FLT1,CHL1,IGSF5,ADGRA3,LINGO1,IGFBPL1,NEGR1,L1CAM,LSAMP,NCAM2,NRCAM,NTRK2,NTRK3,IGSF11,CNTN3,PRTG,SDK2,LRRN3,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,UNC5B,NFASC,OBSL1,LRRC24,TRIO,FSTL5,CADM2,ADAMTSL3" Gene Family 20 Clustered protocadherins genenames.org 3.34E-13 1.77E-10 5.91E-11 4.05E-10 28 64 "PCDHGB4,PCDHGC3,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Gene Family 28 Zinc fingers C2H2-type|BTB domain containing genenames.org 1.73E-12 9.18E-10 2.29E-10 1.57E-09 125 720 "ZNF608,ZNF578,ZFAT,ZSCAN18,ZBTB10,ZNF582,ZNF583,ZNF599,SCAPER,JAZF1,ZNF555,ZNF501,ZNF445,ZNF521,ZFP28,HINFP,ZSCAN23,ZNF337,ZBTB24,EGR3,ZNF391,ZNF549,ZNF461,ZNF585B,ZSCAN30,ZNF589,ZNF605,ZNF44,ZNF234,ZNF274,ZNF559,ZNF276,GLI2,ZNF782,PRDM5,ZNF496,ZBTB49,ZBTB45,ZHX1,ZNF491,ZNF181,ZNF546,ZIC5,ZNF678,ZNF680,ZNF92,ZNF862,CHAMP1,ZNF713,ZNF827,ZNF655,ZNF426,ZSCAN32,ZIK1,ZSCAN2,ZNF615,ZNF844,ZNF793,ZNF493,HKR1,ZNF532,ZNF671,ZNF354C,ZNF568,ZNF331,SALL1,ZFP2,ZNF821,ZFP30,ZNF430,ZNF334,ZKSCAN3,ZFP1,ZNF667,ZNF415,ZHX3,SP2,SP4,ZNF423,ZBTB43,ZNF621,ZNF302,ZSCAN29,ATMIN,ZFP90,ZEB1,ZFPM2,ZNF34,ZNF106,TRPS1,ZKSCAN5,ZNF610,ZNF709,ZNF781,ZFP37,ZBTB14,ZIC1,ZIC2,ZNF711,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZNF45,ZFP41,ZNF540,ZNF70,ZNF74,ZNF138,ZNF142,ZBTB38,ZNF154,ZNF177,ZNF184,ZSCAN26,ZNF189,ZNF195,ZNF213,ZNF225,ZXDA,PRDM10,ZNF30" Gene Family 682 Zinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors genenames.org 1.04E-11 5.54E-09 1.11E-09 7.59E-09 52 206 "ABR,PLEKHH1,OSBPL8,FGD2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,ARHGEF2,PLEKHB1,ARHGAP22,ARHGEF6,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,TIAM2,DNM1,PLEKHA1,AGAP2,AGAP3,PSD2,FERMT2,ADAP1,GRB10,PSD,RASGRF1,RASGRF2,SBF1,RASA3,SH3BP2,FERMT1,ASAP3,CNKSR2,DOK5,SPTB,MPRIP,PHLDB1,ARHGEF9,MCF2L,DOCK9,ARHGAP9,TIAM1,DOK6,OSBP2,PLEKHH2,VAV1,SPATA13" Gene Family 1220 Membrane associated guanylate kinases|PDZ domain containing genenames.org 4.62E-11 2.45E-08 4.09E-09 2.80E-08 42 152 "PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,PICK1,WHRN,SIPA1L1,RIMS2,TIAM2,PARD6A,SHANK1,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,PDZRN4,PTPN13,RGS3,RGS12,FRMPD1,MYO18A,CNKSR2,PREX2,RADIL,MAST1,PDZRN3,PDZD2,ERBIN,PDLIM2,TIAM1,PARD3,SYNPO2,STXBP4,GORASP1" Gene Family 722 Rho guanine nucleotide exchange factors genenames.org 1.61E-09 8.56E-07 1.22E-07 8.38E-07 24 66 "ABR,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,TIAM1,TRIO,VAV1,SPATA13" Gene Family 1293 Minor histocompatibility antigens|FERM domain containing genenames.org 3.51E-08 1.86E-05 2.33E-06 1.60E-05 19 50 "PLEKHH1,EPB41L5,KRIT1,EPB41,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,PLEKHH2,FRMD6" Gene Family 775 Myb/SANT domain containing|Trinucleotide repeat containing genenames.org 5.14E-06 2.73E-03 3.03E-04 2.08E-03 11 25 "EP400,TNRC6C,CASK,MAGI1,NUMBL,NCOR2,MED12,TOX3,TNRC6A,ATXN2,JPH3" Gene Family 694 Protein phosphatase 1 regulatory subunits genenames.org 7.43E-06 3.94E-03 3.94E-04 2.70E-03 36 181 "ELFN2,APC,NCOR1,AATK,PHACTR3,DZIP3,PPP1R16B,ZFYVE16,SPATA2,SACS,TMEM132C,PPP1R1B,FER,GPR12,MAPT,PLCL1,PPP1R1A,HYDIN,PTK2,CSRNP3,TRA2B,PREX2,SLC12A2,MYO16,RBM26,STAU1,ANKRD28,RPGRIP1L,RIMBP2,CSMD1,PARD3,TNS1,TP53BP2,TSC2,ELFN1,PPP1R3F" Gene Family 409 Armadillo repeat containing genenames.org 1.80E-05 9.53E-03 8.00E-04 5.48E-03 14 43 "GPRASP2,ARMC12,PKP4,APC,ARMC8,GPRASP1,ARMCX4,ARMCX2,APC2,ARMCX1,KPNA5,RAP1GDS1,ARMC5,BHLHB9" Gene Family 858 Potassium voltage-gated channel regulatory subunits|EF-hand domain containing genenames.org 1.81E-05 9.60E-03 8.00E-04 5.48E-03 8 15 "DPP10,KCNAB2,KCNAB3,DPP6,KCNIP3,KCNIP1,KCNE5,KCNAB1" Gene Family 21 Non-clustered protocadherins genenames.org 2.89E-05 1.54E-02 1.18E-03 8.10E-03 7 12 "PCDH19,PCDH10,PCDH17,PCDH8,PCDH9,PCDH18,PCDH20" Gene Family 813 "Fibronectin type III domain containing|Protein tyrosine phosphatases, receptor type" genenames.org 4.90E-05 2.60E-02 1.86E-03 1.27E-02 9 21 "PTPRT,PTPRB,PTPRD,PTPRE,PTPRG,PTPRH,PTPRN,PTPRN2,PTPRO" Gene Family 861 Kelch like|BTB domain containing genenames.org 7.80E-05 4.14E-02 2.76E-03 1.89E-02 27 134 "KLHL32,KLHL13,SPOP,ZBTB10,BACH1,RCBTB2,ZBTB24,KLHL3,RHOBTB1,KLHL5,ANKFY1,ZBTB49,ZBTB45,BACH2,KLHL23,KLHL11,BTBD3,KBTBD4,BTBD7,ABTB1,ZBTB43,KLHL7,KLHL4,NACC2,ZBTB14,ZBTB38,GAN" Gene Family 403 Ankyrin repeat domain containing|BRCA1 B complex genenames.org 9.46E-05 5.02E-02 3.14E-03 2.15E-02 41 242 "CASKIN1,HACE1,OSBPL1A,ANK2,BARD1,KRIT1,DGKI,HECTD1,ANKRD35,ANKRD44,CLIP3,SNCAIP,PPP1R16B,DAPK1,GIT2,SHANK1,ANKRD46,FEM1B,ASB3,ANKMY1,AGAP2,AGAP3,ANKFY1,SOWAHA,GIT1,ANKRD16,ANKHD1,RNASEL,ASAP3,ANKRD6,ABTB1,ANKRD36,ANKFN1,MYO16,KANK1,ANKRD28,ANKRD12,ANKRD24,TP53BP2,ANKRD20A2,ANKS1B" Gene Family 863 EF-hand domain containing genenames.org 1.00E-04 5.33E-02 3.14E-03 2.15E-02 38 219 "DST,CACNA1B,CALB1,CALB2,CABP7,CALM1,CAPN3,EPS15L1,MYL6B,CABP1,DGKB,DGKG,AIF1L,RASGRP1,RASGRP2,NCALD,HPCAL4,EFCAB2,CGREF1,GPD2,PLCD4,NKD1,EFHB,NUCB2,PLCD1,SLC25A23,NECAB2,KCNIP3,KCNIP1,RYR3,S100B,SPTAN1,NECAB1,RHBDL3,DNAH7,VSNL1,MICU3,FSTL5" Gene Family 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 1.69E-04 8.96E-02 4.82E-03 3.30E-02 34 193 "ADGRF5,ALCAM,SEMA7A,SEMA4G,IGDCC4,CD86,IGLON5,CNTFR,CNTN1,NECTIN3,CSF1R,BOC,CDON,FCGR1A,FCGR1B,FCGR3A,SEMA4D,FLT1,CHL1,IGSF5,MALT1,PTPRT,VSIG4,IL6R,KIT,NRCAM,CNTN3,SDK2,KIRREL1,OBSL1,TEK,ICAM5,SEMA3B,ADAMTSL3" Gene Family 321 Receptor Tyrosine Kinases|Protein phosphatase 1 regulatory subunits genenames.org 1.72E-04 9.15E-02 4.82E-03 3.30E-02 12 40 "ALK,DDR1,AATK,CSF1R,FGFR1,FGFR3,FLT1,KIT,NTRK2,NTRK3,RET,TEK" Gene Family 396 A-kinase anchoring proteins genenames.org 2.29E-04 1.21E-01 5.61E-03 3.84E-02 10 30 "WASF1,AKAP7,AKAP6,AKAP5,MYRIP,AKAP12,AKAP3,NBEA,MAP2,MYO7A" Gene Family 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 2.29E-04 1.22E-01 5.61E-03 3.84E-02 14 53 "MTA3,EP400,NCOR1,NCOR2,ELMSAN1,DMTF1,EZH1,MSANTD4,MIER3,MSANTD2,SMARCC2,RCOR3,TRERF1,BDP1" Gene Family 736 Immunoglobulin like domain containing|Semaphorins genenames.org 2.32E-04 1.23E-01 5.61E-03 3.84E-02 8 20 "SEMA6A,SEMA7A,SEMA4G,SEMA3D,SEMA4D,SEMA5B,SEMA6D,SEMA3B" Gene Family 720 Regulators of G-protein signaling genenames.org 3.45E-04 1.83E-01 7.97E-03 5.46E-02 8 21 "RGS20,RGS11,RGS9,RGS6,RGS17,RGS3,RGS4,RGS12" Gene Family 1079 Atypical dual specificity phosphatases|Phosphoinositide phosphatases genenames.org 4.14E-04 2.20E-01 9.04E-03 6.19E-02 10 32 "SYNJ1,SYNJ2,MTMR3,MTMR2,MTMR7,INPP5K,INPP1,INPP5B,OCRL,MTMR14" Gene Family 366 Ubiquitin specific peptidases genenames.org 4.25E-04 2.26E-01 9.04E-03 6.19E-02 14 56 "USP31,USP35,USP37,USP6,USP2,USP3,USPL1,USP21,USP19,USP51,USP47,USP33,USP22,USP1" Gene Family 362 Ring finger proteins|WD repeat domain containing genenames.org 5.31E-04 2.82E-01 1.08E-02 7.43E-02 41 262 "WDR35,APAF1,LRBA,LRWD1,COPB2,PLAA,SEC31B,DCAF4,DCAF8,WDR20,DYNC1I1,CORO2B,RACK1,WDR83,NBEA,STXBP5,POC1B,NLE1,STRN3,PPP2R2B,PPP2R2C,BCAS3,WDR25,EML5,NWD1,ELP2,FBXW7,KIF21A,AMBRA1,SEC31A,WDR37,WDR47,IFT122,MAPKBP1,MLST8,FBXW11,TBL1X,DMXL2,HIRA,EML6,AAAS" Gene Family 651 Mitogen-activated protein kinases genenames.org 5.86E-04 3.11E-01 1.15E-02 7.90E-02 6 13 "MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,MAPK12" Gene Family 741 SH2 domain containing genenames.org 7.94E-04 4.22E-01 1.49E-02 1.02E-01 20 101 "BTK,SOCS6,CHN1,CHN2,SH2B1,SOCS5,FER,FYN,GRB10,JAK2,MATK,SHC3,PIK3R1,SH3BP2,SHC4,SLA,TNS2,TNS1,VAV1,SOCS4" Gene Family 912 "Adhesion G protein-coupled receptors, subfamily B" genenames.org 8.67E-04 4.60E-01 1.49E-02 1.02E-01 3 3 "ADGRB1,ADGRB2,ADGRB3" Gene Family 1325 Synapsins genenames.org 8.67E-04 4.60E-01 1.49E-02 1.02E-01 3 3 "SYN3,SYN1,SYN2" Gene Family 774 Transmembrane and coiled-coil domain containing genenames.org 8.67E-04 4.60E-01 1.49E-02 1.02E-01 3 3 "TMCC3,TMCC2,TMCC1" Coexpression 19621087-Table1d Mouse EmbryonicStemCell_Abranches09_1170genes GeneSigDB 5.00E-47 5.68E-43 5.68E-43 5.63E-42 207 651 "GALNT16,ADCY6,RNF157,PCDH19,OSBPL6,TXNDC16,ALCAM,ABCD2,ANK2,APBA2,CASK,CADPS,TMEM108,DPY19L3,ADGRB2,MPDZ,AP1M1,SGCE,CACNA1G,PTBP2,SPAG9,CBLN1,LONRF2,CDH2,DCLK1,MAGI1,CACNA2D2,RCBTB2,SOCS6,SLIT2,LHX2,FBXO7,HOMER3,COL4A5,LETMD1,NECTIN3,SLC35F1,FAM171B,ANKRD44,CLIP3,SNCAIP,LRIG1,SIPA1L1,CNTNAP2,SLITRK5,DZIP3,PHF14,GPSM1,BOC,DOCK4,HDAC9,TCAF1,RASSF2,SCRN1,DBN1,JAKMIP2,RHOBTB1,TMCC2,USP3,CDON,DPYSL2,EDNRB,PHC2,YAF2,PHF20L1,PLXNC1,GPHN,STX2,EXTL2,KATNAL1,ADGRV1,EYA1,TBC1D16,TMEM132C,OLFM1,SPSB4,FGF13,MEX3B,EVL,NBEA,FYN,MEGF10,TOX3,ADGRA3,GP1BB,GRIK5,RNF165,SOX21,ADAMTS6,TOX2,ZHX1,BACH2,NEGR1,MSL1,NKD1,LRRTM1,CAMK2N2,LSAMP,SMAD1,MAN2A2,MARK1,MEIS1,MEIS2,PPM1L,MKLN1,MMP16,MN1,MSI1,SAMD14,MYO5A,NELL2,NOVA1,NRCAM,CNTN3,PAX6,PCDH8,GPR173,TMOD2,SEMA5B,PCDH18,PURG,LRP12,IRX1,PPP2R5E,PKIA,MAPK10,GDPD1,RELN,LAMA1,PTH1R,PTPRD,PTPRN2,NKAIN1,USP47,FAT4,GAL3ST4,RFX3,ZFHX4,CCDC82,ROBO2,ATAT1,CLIP1,RTN1,RXRA,SEMA6D,SATB1,CSRNP3,SCN8A,TNFRSF19,GALNT10,RASA3,HSPA4L,PPM1E,ARX,FHOD3,CNKSR2,DZIP1,CXXC4,IFT122,MBD5,TMCC1,SOX11,SP4,NFASC,CLSTN2,ERBIN,MPRIP,ELOVL4,SEPT3,SYNE2,SYT1,PJA1,ADGRL3,TCF4,SATB2,ZEB1,TCF12,PCDHGA11,PCDHA1,GPR161,ENHO,ASXL3,NR2E1,TRIO,STXBP4,SSBP2,TTC3,RPRM,UBE2H,FLRT2,BCL2L13,MTCH1,VLDLR,ZIC1,ZFP41,ATP6V0E2,REEP1,DPYSL5,ZXDA,STOX2,WNK2,FZD3,ST7,ADAMTS10,NHSL1,ST8SIA2,SENP7" Coexpression 18223198-TableS3 Human Brain_Chen-Plotkin08_747genes GeneSigDB 8.42E-45 9.56E-41 4.78E-41 4.74E-40 192 594 "SYN3,ADD2,KIAA1324,DOC2A,AMPH,PPFIA4,PKP4,APBA2,KCNAB2,GAS7,TMEFF1,ARHGDIG,ATP2A2,ATP6V0A1,ADAM23,ADGRB2,CFLAR,SYNJ1,CACNA1G,RAB29,WASF1,DDR1,CACNB4,KALRN,CAMK2A,CAMK2B,HIP1R,LDB2,DCLK1,LARGE1,DLGAP2,DLGAP1,CHGB,CHN1,B4GALT6,NRXN3,QKI,SULT4A1,LY86,FHL5,CNR1,CABP1,PREPL,CRYM,IPCEF1,SIPA1L1,VCAN,PDE4DIP,CNTNAP2,DZIP3,ERC2,GPRASP1,ARHGAP32,DCTN1,SNAP91,SV2B,DYNC1I1,DOCK2,DPP6,DTNA,ECM2,SEZ6L2,RASGRP1,EGFR,EGR3,AASS,RGS17,SRPK3,EMX2,ENO2,NCALD,RASL12,NRN1,ABCA8,PTK2B,TUBB3,FCGRT,OLFM1,FGF13,BAIAP2,HPCAL4,RASL10A,CAMKK2,CHL1,GABRB3,GAD1,HIGD1B,GATM,GFRA2,RUNDC3A,GNAO1,PCLO,STMN2,CIT,PTPRT,GSN,ACOT7,HMGCR,HNMT,IFI16,SHISAL1,ITPKA,ITPKB,KCNB1,KTN1,L1CAM,LAMP2,MAP2,MATN2,MEF2C,MEST,SCAMP5,TAGLN3,FXYD7,NELL2,NPTX1,OPA1,PDE4A,SERPINI1,SNX10,PLXNB1,TRHDE,FSD1,PPP3CA,PRKAR1B,PRKCB,DIRAS2,PTPN13,PTPRB,PTPRN,PTPRO,IQSEC3,SUSD4,RDX,ZMAT4,RGS4,RNASE1,NUDT11,ZFHX4,PNMA8A,FBXW7,RTN1,CSRNP3,CNKSR2,WDR47,PKNOX2,ARHGEF40,OGDHL,SNAP25,SNCA,FAIM2,NMNAT2,ITPRID2,ERBIN,ELOVL4,STX1A,KANK1,ARHGEF9,PLCB1,SYN1,SYN2,SYP,SYT1,SYT5,KIAA1107,TBL1X,SATB2,CUX2,TCF12,PHF24,TNS2,ICAM5,RIMBP2,R3HDM1,PARD3,TNS1,RUNDC3B,TUBB2A,UCHL1,VSNL1,WIPF1,KLC2,ZIC1,NDRG4,REEP1,ZNF184,SLC30A3,SLC17A7,KCNAB1,ACTR3B,NETO2,AP3B2" Coexpression M2369 Genes down-regulated during differentiation of Oli-Neu cells (oligodendroglial precursor) in response to PD174265 [PubChem=4709]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.37E-35 2.69E-31 8.96E-32 8.88E-31 261 1080 "ASIC1,FMNL2,TMCC3,PCDH19,TBC1D14,KIAA1324,WDR35,ALCAM,OGT,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,GAS7,BCAS1,TNRC6C,SHROOM2,SEMA4G,TMEFF1,ASPA,DYNLL1,TMEM108,N4BP2L1,ATP6V1G2,BCHE,DST,WASF1,MYRF,CFAP410,DDR1,CACNA2D1,THSD7A,KALRN,HIP1R,ARHGEF25,DCLK1,ZNF445,CFL2,SOCS6,CHN2,CLCN3,TPP1,FAM189A2,QKI,IGLON5,COL4A5,COL9A1,COL11A2,GAL3ST1,RTTN,CNRIP1,ANKRD44,NCOR1,CLIP3,AATK,CSF1,LRIG1,PPP1R16B,RUBCN,USP6NL,DOCK4,HDAC9,KATNAL2,RASSF2,LIN54,KIAA0586,DBN1,B3GAT3,MFAP3L,KIAA0753,LYPD1,TMCC2,NR1D2,CPEB2,DTNA,ABCC5,KLHL5,MBNL2,PLXNC1,PLEKHA1,CERCAM,SRPK3,TMEM35A,EPB41L2,NCALD,SPEG,KATNAL1,TBC1D16,TUBB3,CEP78,FCGRT,STRADA,AMOTL2,MEX3B,SEMA4D,WDR83,SPECC1,APOPT1,FAM49B,FUT9,BRSK1,FYN,ZMAT1,GALC,TMEM8B,INPP5K,GATM,SRCAP,GFRA2,PCDH17,RUNDC3A,GNAO1,GPD1,GPR37,TPPP,GRIA2,FAM19A2,COQ10A,SOX21,MAP4K5,HAS2,PADI2,FRMD5,HLF,SYNPO,NEGR1,LRRC75A,SHISAL1,NKD1,GAREM2,TJAP1,FAM69A,ITGA7,JAK2,CDH20,TTYH2,LSAMP,ZFYVE27,MAP6,MAPT,MARK1,MATN2,MBP,CHIC1,MGAT3,PPM1L,POC1B,MPP2,MXI1,MYO6,NCAM2,NINJ2,NRCAM,IGSF11,PRTG,PDE4B,PDE4D,ENPP2,SERPINI1,SEMA5B,RETREG1,XRN1,PLEC,PLXNB1,PURG,PDZRN4,SEPT4,EPB41L4B,FA2H,PPARA,PPP2R2B,LRRN3,KANSL1,RASGEF1B,PRKAR1B,RELN,BCAS3,PIGG,MTMR10,PTPRE,NKAIN1,RBBP6,ZDHHC14,DUSP15,RGS3,RNASEL,PCMTD2,MAP6D1,ATAT1,KCNIP3,S100B,SEMA6D,KIF21A,FAM102A,MYO18A,FHOD3,DZIP1,ST8SIA1,LIMS2,FAM214B,SIRT2,CCDC88A,ZFP1,ABTB1,INAVA,KIF13A,LMBRD1,TEX2,UNC5B,DBNDD2,CDK19,NFASC,LHPP,ERBIN,ZSCAN29,PHLDB1,KANK1,PRRC2C,SYT1,ANKRD28,ANKRD12,PDLIM2,ADGRL3,IQCE,ATMIN,WSCD1,KIAA0930,TRIM2,TCF12,SYNE1,DOCK9,SLC44A1,HEY1,CABIN1,TNS1,TRIO,RUSC1,CA14,TST,TTC3,HIRA,UBE2H,UGT8,FLRT2,WRN,RICTOR,ZNF24,ZNF32,NDRG4,LYPD6,REEP1,ZSCAN26,ZFAND5,CADM2,NAV3,URM1,FAM13C,AMN1,RTN4,NHSL1" Coexpression 19621087-Table1e Mouse EmbryonicStemCell_Abranches09_919genes GeneSigDB 6.27E-32 7.12E-28 1.78E-28 1.77E-27 162 555 "ASIC1,ACHE,NCKAP5,ADCY5,ADCY8,ADD2,RNF150,ARHGAP20,PCDH10,LCORL,APC,SEMA4G,RNF182,ATP6V1G2,BCL7A,SYNJ1,ARHGEF7,CACNB4,CALM1,KALRN,HAP1,RUNX1T1,CDC25B,DCLK1,ARHGAP33,EVI5L,MAGI1,CDO1,CFL2,CHGB,CHN2,CHRNA4,SLIT2,NRXN3,IGLON5,CNTN1,AKAP6,CNTNAP2,ERC2,GPRASP1,DNM1,CD99L2,EDIL3,EDNRB,KMT5B,APC2,NRN1,CLVS1,IP6K2,PSD2,ST6GALNAC3,DLL3,STAU2,TPPP3,ZMAT1,GABBR1,CHL1,TMEM8B,SRRM4,CYP46A1,RAB40B,GP1BB,GRIA2,PARD3B,GABARAPL2,IGFBPL1,INSM1,KCND2,KCNN1,KIF5A,L1CAM,LMO2,LSS,MAPT,MARK1,MBD1,TAGLN3,MXI1,RTL5,MYT1,NFIX,NPR2,NTRK2,GPR137C,PCDH9,GNG2,SERPINI1,NALCN,GPSM2,SMOX,DRAM2,POU6F1,MINDY2,PCDHB17P,LRRN3,NKAIN4,RASGEF1B,MAPK10,VPS13C,CNTLN,PTPRO,TUG1,RBBP6,KHDRBS2,RNASEL,MEG3,ATAT1,HES6,SMPD3,MRAS,ZFP30,SYBU,DZIP1,ST8SIA1,WDR47,SIRT2,CCDC88A,NAPB,ZKSCAN3,SMARCD3,LIMCH1,SNAP25,MYO16,KDM4B,GLT8D1,CDK19,SST,TTBK2,STXBP1,KLHL7,ARHGEF9,CAMTA1,ADGRL3,TCF4,CUX2,TRIM2,PCDHB10,PCDHB7,PCDHB3,PCDHA1,THRA,NR2E1,RGMB,TRPS1,TUBB2A,UCHL1,FLRT2,VLDLR,NPDC1,TRIM9,NDRG4,MKRN3,CELF4,FSTL5,CADM2,GDPD5,PRDM8,TMEM178A,NAV3,NETO1,DPF3,ST8SIA2" Coexpression 19185848-TableS1 Mouse StemCell_Read09_438genes GeneSigDB 6.84E-31 7.77E-27 1.56E-27 1.54E-26 109 299 "ASPHD1,ASIC1,KLHL32,ADCY5,ADD2,SEMA6A,BIN1,APC,APLP1,AQP6,SEMA4G,CADPS,ARHGEF7,CACNA1B,CACNB4,THSD7A,SYNGR3,DCLK1,MAGI1,CHGB,RAB33A,FBXO7,CNTN1,SCRN1,DBN1,ELMO1,SNAP91,SV2B,CPEB2,DTNA,EDIL3,SEZ6L2,PHF20L1,RGS17,RCAN2,APC2,CLVS1,TUBB3,GABBR1,GPR162,GGT7,AIFM3,GP1BB,STMN2,UBE2QL1,IGFBPL1,CELF5,DISP2,KIF5A,L1CAM,TTYH2,LSAMP,MAPT,MYT1,NPR2,NPTX1,NRCAM,PDE4D,GPR173,SERPINI1,PIK3R1,PLCD1,SH3KBP1,MINDY2,PKIA,PRKCB,MAPK10,SPDL1,EML5,NKAIN1,PID1,RBBP6,PRRT2,RNASEL,KLHDC8A,ATAT1,RTN1,SCN8A,PPM1E,WDR47,NAPB,CPEB4,MAST1,SNAP25,PDZRN3,DOP1A,NFASC,SEPT3,STXBP1,PLCB1,SYP,SYT1,MCF2L,DMXL2,PCDHB9,GPRIN3,ZFPM2,THRA,ASXL3,TRIO,TUBB2A,MGAT5B,PCDH20,NDRG4,CELF4,MAP3K12,CADM2,GDPD5,ST8SIA2" Coexpression M17728 Genes down-regulated in brain from patients with Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.07E-29 1.03E-24 1.72E-25 1.70E-24 270 1237 "ACHE,ABHD6,C3orf14,ACTN1,OGT,MAP4K3,APBA2,KCNAB2,APC,TMEFF1,RGS20,CADPS,NUMB,DYNLL1,ATP2A2,ATP2B2,ATP6V1G2,ADAM23,ADGRB2,ADGRB3,SYNJ1,NAE1,SCAPER,WASF1,CALM1,KALRN,CAMK2A,SLC25A14,RUNX1T1,CLDN10,CCK,LDB2,CCNH,USP6,SYNGR3,ZMYM4,LARGE1,DLGAP2,CDO1,DLGAP1,CCPG1,CHN1,B4GALT6,SLIT2,LHX2,CPNE6,STOML1,CLTC,SULT4A1,CNR1,CABP1,LETMD1,MAGED1,RCHY1,TBPL1,COX4I1,PREPL,AKAP12,CRMP1,RNF14,CLIP3,CRYM,CS,CSNK1G3,PDE4DIP,CNTNAP2,ARHGEF4,RIMS2,RIPOR2,MATR3,DGKB,BRINP1,ELMO1,SACS,SV2B,CHRDL1,DMD,HS3ST2,DYNC1I1,CASP8AP2,DNM1L,GOLT1B,EDN3,CNNM1,EIF5,COPS4,TENM1,ENO2,RCAN2,RABEPK,DENND4A,GMPR2,NRN1,REEP2,F8,ARMCX1,FAM198B,SH3YL1,PTK2B,TUBB3,FECH,OLFM1,FGF13,FGFR3,FHL1,ATP5PD,UBE2E3,HPCAL4,SEC23B,AGAP2,SYNCRIP,DCTN2,STAMBP,CAMKK2,ATP6V1H,ATP2C1,CSPG5,OGA,GAA,GABBR1,CHL1,GABRB3,GAD1,GALC,B4GALNT1,NFU1,RUNDC3A,TCERG1,COPS8,TOX3,GLUL,GNAL,GNAO1,FERMT2,PCLO,STMN2,GRIA2,BTN2A1,PTPRT,AP4S1,GUCY1B1,ACOT7,HSF2,SMAP1,IDH3B,IGF1,FAM69A,ITPKA,JAK2,KCND2,KCNF1,KCNN2,KIF2A,KIT,IPO5,L1CAM,MATK,TM6SF1,LRP1B,SHC3,MEF2C,THYN1,TAGLN3,FXYD7,NEFM,NEFH,NELL2,NNAT,NPY,OPA1,PCSK1,PDCD2,PDE4B,PDE4D,ABCB1,SERPINI1,SNX10,FAM216A,LRP12,PSAT1,SCHIP1,MAGEL2,FSD1,PPP2R2B,LRRN3,PPP2R5E,PPP3CA,PRKAR1B,PRKCB,MAPK9,MAPK10,DIRAS2,SNRK,ELOVL2,PTN,PTPRE,PTPRN2,PTX3,RAP1GDS1,OXR1,RGS4,NUDT11,ROBO1,RPE,RPL15,FBXW7,MEG3,KCNIP1,CLIP1,RTN1,SCP2,HSPA4L,CNKSR2,CCDC92,SEC31A,DZIP1,SLC4A3,PKNOX2,ELMO2,SNAP25,SNCA,FAIM2,USP33,NMNAT2,GLT8D1,PEG10,DDN,CLASP2,SST,ELOVL4,STX1A,STXBP1,NSFL1C,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SYT5,PJA1,TAF9,ADGRL3,DMXL2,PUM2,ZMAT3,AKTIP,HEY1,R3HDM1,TRO,RUSC1,TTC3,TUBB2A,UBC,RPRM,UCHL1,FLRT2,VLDLR,VSNL1,USP32P2,NDRG4,ZNF142,ZNF184,SH3GLB2,MFF,KCNAB1,RTN4,ACTR3B,NETO2,AP3B2,JPH3" Coexpression 17880687-TableS2 Human Embryo_Heim07_2325genes GeneSigDB 6.44E-22 7.31E-18 1.05E-18 1.04E-17 299 1565 "CLK4,EMILIN3,NDRG2,FMNL2,TMEM132B,ADD2,AXIN2,PCDH19,TBC1D14,TAOK1,SEMA6A,SPOP,SYT13,PDZD4,BIN1,CDC42BPA,PKP4,APBB2,PHYHD1,VAT1L,SHROOM2,CDC14B,IGDCC4,CADPS,RASL11B,STX16,KIF1A,BACH1,NRP2,PROM1,SYNJ1,CASTOR3,SGCE,CA12,DDR1,CACNA2D1,THSD7A,PTBP2,RUNX1T1,CBLN1,CLDN10,KYAT1,SEPT7,CRLF1,CHN2,PLEKHB1,SLIT2,FAM189A2,VAX2,ABCG2,FAM19A5,HECTD1,HOMER3,ARHGEF6,CNR1,AKAP7,ARMC8,COL9A3,AHCTF1,BAG4,FAM171B,C2CD2,RBM39,SNCAIP,CSNK1G3,SIPA1L1,PDE4DIP,CNTNAP2,CTH,HDAC9,GAPVD1,TBC1D5,MATR3,TMEM170A,DAPK1,BRINP1,DBT,PITPNC1,YTHDC1,ZBTB24,LYPD1,GSDME,MTX3,FAM107B,DYNC1I1,NR1D2,DPP6,RCAN1,DTNA,DUSP9,DNM1L,TSPAN5,EDN1,FEM1B,FCF1,YAF2,FAM13A,EGFR,TMEM132E,TUBD1,EPB41,EPB41L2,ERBB2,RASL12,TBC1D16,ACSL4,DLC1,OLFM1,AMOTL2,POLK,MEX3B,SEMA4D,FLT1,TMEM107,UFM1,PDLIM5,CSPG5,MPP6,GABBR1,ZNF44,GAD1,IQGAP2,CPLX2,IGSF5,GCNT2,ARFIP1,SESN1,PCDH17,GLI2,TOX3,TNRC6A,ZNF638,KIAA1958,KDM2B,HTATSF1,GNAO1,FERMT2,LNX1,GPD2,PRUNE2,LPAR4,DIDO1,ATOH8,RASSF8,HAS2,TOX2,ZHX1,BACH2,MIER3,AGFG1,IFI16,RBPJ,IL6ST,ZNF678,ITPKB,KCNN2,L1CAM,CAMK2N2,LIMS1,PAXBP1,SMAD1,SMAD9,MARK1,AQP11,MBNL1,CHST6,SHC3,MEIS1,MEIS2,MID1,PPM1L,MN1,MPP2,TAGLN3,MXI1,MYO6,RTL5,NCAM2,NEFH,CCDC13,NFYA,NPTX2,SLC11A2,CDK18,PRTG,PDE4B,GNG2,PFKFB2,SEMA5B,PIK3C2A,ZNF655,SNX10,GPSM2,MTRF1L,PURG,EPB41L4B,PPP1R1A,PPP3CA,KANSL1,PRKAB2,CEP41,PRODH,PTPRG,ZSCAN2,TTC13,USP47,ZNF493,RET,FIGN,RFX3,RGS3,RGS4,PRIMA1,RIC8B,EXD2,GSTCD,MRAP2,RPE,BAALC,SPIN3,STK32B,HUNK,CLIP1,AP1AR,MAPK12,SEMA6D,SATB1,ATXN2,FNIP1,PEAR1,TRA2B,RASA3,FERMT1,ASAP3,CHD9,CNKSR2,CCDC92,ANKRD6,PREX2,FAM214B,KANSL3,SEPHS1,CCDC88A,KBTBD4,CPEB4,GKAP1,LIMCH1,PDZD2,SOX3,SOX11,DOK5,PEG10,SPTAN1,TSPYL2,RBM26,LMO3,NXT2,SOX21-AS1,MPRIP,KLHL7,PRRC2C,SYNE2,TMEM150C,SYN2,PDLIM2,TBL1X,KLHL4,WSCD1,TCF4,OBSL1,PCDHAC2,TEK,AKTIP,SLC44A1,TIAM1,LRRC8A,FAM124A,TP53BP1,RGMB,TRIO,TRPS1,DCBLD1,RPRM,UBE2H,FLRT2,CCDC136,VSNL1,RBFOX3,WIPF1,ZIC2,KCNT2,ATP6V0E2,MAP3K12,STOX2,RTN4,UBE3B,FBXO36,JMJD1C,SPATA13" Coexpression 19605494-TableS2 Mouse Skin_Driskell09_1477genes GeneSigDB 2.06E-21 2.34E-17 2.93E-18 2.90E-17 193 872 "KCNH8,ABHD6,TMCC3,GALNT13,AXIN2,OSBPL1A,OSBPL6,C1QTNF1,LTBP4,OGT,CDC42BPA,MAP4K3,APBB2,VAT1L,PRX,ARNTL,ASPA,TMEM108,SLC4A4,RNF182,KIF1A,DOCK11,BCHE,DST,ARHGEF7,IL33,CACNA1B,THSD7A,LDB2,CBFA2T2,CDH2,DCLK1,MAGI1,DLGAP1,NOG,CHN2,PLEKHB1,SLIT2,FAM19A5,CNTN1,ABI3BP,SLC35F1,RBM39,ABCG1,LRIG1,VCAN,FAM169A,SLITRK5,HDAC4,RASSF2,KCTD8,DAPK1,MFAP3L,RHOBTB1,SNAP91,SPOCK3,GRIN3A,RAB39B,DMPK,DMTF1,DNM1L,PHF20L1,MBNL2,PLEKHA1,SRPK3,VPS13B,LRRC17,ETV1,CHST15,FGF1,FGF14,FOXO3,FOLR2,NBEA,SPECC1,CAMKK2,MEGF10,CHL1,GATM,GCNT2,GHR,PPARGC1A,SPIN1,GPD2,LPAR4,GRIA2,NEGR1,IGF1,LRRTM1,METTL21A,KCND2,KCNQ3,LIMS1,LSS,MAPT,MBP,MEIS1,MEST,MMP17,MN1,MYT1,NCAM2,NFIX,NNAT,NTRK2,NUCB2,IGSF11,P2RX7,PCDH9,PCSK5,PRTG,PDE1C,PDE3A,TMOD2,DUSP26,NALCN,RETREG1,PLCL1,PURG,STRN3,SCHIP1,FA2H,LRRN3,PRKAR1B,MASP1,RELN,GDPD2,PTH1R,PTPRD,PTX3,TMEM255A,FAM184A,BEND5,KHDRBS2,DUSP15,FIGN,RFX3,MRPS18A,ZFHX4,RORB,FBXW7,LRRK2,HUNK,RYR3,S100B,MAPK12,SCN8A,HSPA4L,KIF21A,ASAP3,FHOD3,NLGN1,ANKRD6,WDR37,SNCA,FAM126B,SPP1,ERC1,ATP10B,NKAIN2,SS18,RGL1,SULF2,ARHGEF9,TMEM150C,TAL1,ADGRL3,TCF4,CUX2,CHST8,CDH22,SLC44A1,ASXL3,PRRT1,RGMB,AMACR,SSBP2,VLDLR,TSPAN11,P2RY12,RICTOR,ZIC1,TRIM9,LYPD6,CELF4,FTSJ1,ZFAND5,CADM2,ADAMTS9,SEMA3B,NAV3,RGS7BP,JMJD1C" Coexpression M1533 All significantly down-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.71E-21 3.08E-17 3.43E-18 3.40E-17 186 830 "FMNL2,TMCC3,MTUS1,HECW2,OSBPL8,TAOK1,ADGRF5,SPOP,FAM135A,APBB2,SHROOM2,PRX,ARRB1,SEC11C,GPR146,CFLAR,DST,MTMR2,THSD7A,CALM1,CAST,LDB2,KRIT1,CD38,LRBA,LRRFIP1,TPP1,QKI,ARMC8,COL4A5,NECTIN3,CLOCK,NCOR1,SNCAIP,CSNK1G3,PDE4DIP,PPP1R16B,CYBB,DOCK4,MYADM,RIPOR2,ARHGAP24,ZFYVE16,LIN54,AIF1L,DBT,PITPNC1,TMCC2,CPEB2,SLC12A6,DPYSL2,RCAN1,DTNA,DNAJB6,E2F5,EBF1,TSPAN5,EDNRB,HIPK3,KLHL5,TMTC1,FRY,OPTN,PHF20L1,MBNL2,CALCRL,RCAN2,EPHB1,SPEG,ARMCX1,ACSL4,DLC1,ST3GAL6,MED12L,FLT1,FAM49B,ST6GALNAC3,FYN,GALC,IQGAP2,SYT17,PCDH17,MALT1,FERMT2,GPD2,STON1,LPAR4,PARD3B,GSN,GUCY1A1,ZHX1,SYNPO,AGFG1,IL6ST,ITPKB,LIFR,LIMS1,LMO2,MAPT,MARK1,SHC3,MEF2C,KITLG,MYO6,NEK1,PDE4B,PDE4D,PFKFB3,ABCB1,SERPINI1,RETREG1,PLCL1,SMIM7,SCHIP1,ING3,MINDY2,SNRK,PTPRB,PTPRG,PTPRO,RIPOR1,TUG1,RBBP6,ZDHHC14,CCDC82,KIRREL1,PCMTD2,CLIP1,ATXN7,SCN7A,GALNT10,SGK1,FAM102A,MYO18A,FNDC3A,ABLIM3,PREX2,BTBD3,EPN2,SLC12A2,CPEB4,MBD5,LMBRD1,FAM126B,USP33,SP2,KDM4C,TEX2,ARHGAP26,DDN,TROVE2,ITPRID2,NXT2,ST5,MPRIP,KANK1,SULF2,VPS13A,TMEM150C,TACC1,MTCL1,FAM208A,PDLIM2,ADGRL3,PUM2,TNS2,GPRIN3,FRYL,TEK,C18orf54,AP4E1,TLR4,TPM1,NPL,SSBP2,TUBB2A,SGK3,TUBB1,RICTOR,SPIRE1,RNF103,SEMA3B,PLSCR4,FAM13C,MSRB3,FRMD6" Coexpression M2110 Genes whose expression significantly and positively correlated with the density of CALB1-positive [GeneID=793] GABAergic interneurons in the BA9 brain region across all subjects with psychiatric disorders. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.17E-19 2.46E-15 2.46E-16 2.44E-15 135 548 "ABR,ACTN1,OSBPL1A,DOC2A,AMPH,APLP1,FAM131A,MADD,ATP1A3,ATP2A2,ATP6V0A1,ADAM23,ADGRB2,SYNJ1,CACNA1A,CALB1,CALM1,KALRN,CAMK2B,CAMK2G,CCK,LDB2,SYNGR3,DCLK1,CHGB,CHN1,B4GALT6,CLTB,MAGED1,PREPL,CRHBP,CRMP1,CLIP3,CRYM,SOCS5,SLITRK5,PPP1R16B,PUM1,DOCK4,TM9SF4,DGKB,SCRN1,BRINP1,DCTN1,ELMO1,DNM1,DYNC1I1,DPP6,ABCC5,ANKRD46,OPTN,EGR3,EIF5,ENO2,RCAN2,NCALD,PTK2B,TUBB3,SEC24B,FHL1,UBE2E3,KHDRBS3,STAU2,SARAF,OGA,CHL1,GABRG2,SYT17,RUNDC3A,COPS8,PRUNE2,STMN2,GRIA2,GUCY1B1,ACOT7,HMGCR,IDH3A,IDH3B,KCNF1,MAN2A2,MAPT,MBNL1,LYRM9,NELL2,NNAT,NPY,NPTX1,DPY19L2P2,PCDH8,PCSK1,SERPINI1,PKM,SCHIP1,NECAB2,PRKACB,MAPK9,PSMA6,PTPRN2,RGS4,SLC25A36,RTN1,SARS,SCAF8,CNKSR2,BTBD3,WDR47,SNAP25,NMNAT2,MYCBP2,LMO3,SST,STX1A,STXBP1,ARHGEF9,SYT1,KIAA1107,PHF24,PUM2,TIAM1,ICAM5,BEX4,RUSC1,TTC3,TUBB2A,UBC,UCHL1,VSNL1,NDRG4,REEP1,ZFAND5,RNF103,SLC17A7,KCNAB1,RTN4,HNRNPA3" Coexpression M4391 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of TP53 [GeneID=7157] off adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.48E-19 2.82E-15 2.57E-16 2.54E-15 233 1172 "ABR,ABHD6,EMILIN3,ELFN2,ADCY6,KIAA1211,ADRB2,TBC1D14,KIAA1324,C1QTNF1,USP35,CARNS1,APAF1,TNRC6C,SHROOM2,ZFYVE28,ARRB1,MARCH3,ASPA,MARK4,ATP2B2,ALDH7A1,ADAM23,BID,CFLAR,KSR1,BMP7,MYRF,BAIAP3,LDLRAD4,CABP7,KALRN,CAMK2B,CAMK2G,CAPN3,CAST,HIP1R,USP6,CBFA2T2,ENTPD2,DCLK1,CACNA2D2,ABCG2,CNGA3,ARHGEF6,AKAP7,FAM149A,WHRN,COL9A3,NRG2,ZNF385A,ABCG1,SUSD5,VCAN,CST3,UBXN2A,GREB1,ARHGEF4,GPSM1,USP6NL,SEC14L5,DOCK4,KIF26A,MAML1,BRINP1,KLHL3,TMCC2,WDR20,ABCC5,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,TMEM35A,EMX2,ENO2,VPS13B,EPB41,MTSS1L,CEP85L,APC2,ADGRV1,F8,FAM198B,CHST15,STRADA,FECH,FGF1,FGF11,FGF13,FGFR3,BAIAP2,MEX3B,FOXF2,AGAP3,SEMA4D,FLNC,C2orf88,TMEM107,HVCN1,ATP6V1H,NSG1,OGA,FYN,MEGF11,MEGF10,GAA,GAD1,ZNF234,C15orf41,SEPT9,GATM,ALDH1L1,GCNT2,GDF9,AHDC1,CSDC2,GHR,KDM2B,MAP7D2,GPT2,PRRC2B,MCHR1,GPR37,DIDO1,GRM8,GSTT2,BVES,UBE2QL1,TOX2,FRMD5,FRMD3,INSYN1,SHISAL1,KNDC1,DISP2,INPP5B,LRRTM1,ITGAM,ITPKB,KCNB1,KCNK3,CYP27C1,TTYH2,LIFR,PAXBP1,ASPRV1,SMAD9,GPR155,MAP6,MBNL1,LOC643201,AFF1,MN1,NRBP2,MX1,MXI1,MYO6,MYT1,TREM2,DPY19L2P2,GNG2,ABCB1,ZNF655,RETREG1,EPB41L4B,FA2H,FITM2,VPS13C,FAM184A,MSANTD2,ALG9,PCMTD2,GLDN,MAP6D1,MEG3,HUNK,KCNIP3,HES6,PEAR1,GALNT10,FAM102A,ARX,KIF16B,DZIP1,NBPF1,WDR47,ARHGEF40,ELMO2,INAVA,SNRPN,KDM4B,DOP1A,UNC5B,ZBTB43,DIP2A,ARC,C12orf76,MTCL1,CAMTA1,MCF2L,EXOC7,TBCEL,ZFP90,TRIM2,DOCK9,SLC35G2,VWCE,ZMAT3,AKTIP,RIMBP2,TNS1,TSC2,VSNL1,TSPAN11,LAT2,WNT7A,ZIC2,ZNF708,USP32P2,ATP6V0E2,LYPD6,REEP1,EML6,ZNF195,GDPD5,STOX2,FAM13C,DOCK8,MARCH8,ZNF30,JPH3" Coexpression M2115 Genes correlated with proneural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.76E-19 4.27E-15 3.56E-16 3.53E-15 65 177 "ALCAM,CASK,TMEFF1,ATP1A3,ADGRB3,BCL7A,WASF1,DGKI,ARHGAP33,CLGN,RAB33A,VAX2,CNTN1,CRMP1,CSNK1E,MATR3,DBN1,ZNF804A,DPP6,TMEM35A,EPB41,EPHB1,NCALD,AMOTL2,CSPG5,DLL3,GABRA3,TOX3,CBX1,GNG4,LPAR4,GRIA2,KAT7,RNFT2,RBPJ,STMN1,MAP2,MAPT,MMP16,MYT1,P2RX7,DUSP26,NLGN3,PURG,NKAIN1,ATAT1,SATB1,ZNF821,PPM1E,FERMT1,FHOD3,CXXC4,MAST1,INAVA,TMCC1,SOX11,CLASP2,ZC4H2,ARHGEF9,ADGRL3,TTC3,ZNF711,REEP1,ZNF184,HRASLS" Coexpression M4500 Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.54E-18 5.16E-14 3.97E-15 3.94E-14 181 854 "OSBPL8,SPOP,ALCAM,AMPH,OGT,CDC42BPA,PKP4,PARG,APBB2,APC,CASK,RGS20,CDK13,NCOA1,NUMB,EIF4G3,BARD1,BLM,DST,ST3GAL5,SYNJ2,ARHGEF7,FUBP1,MTMR3,WASF1,SPAG9,KRIT1,USP6,CDH2,ZMYM4,LRRFIP1,FOXN3,SOCS6,SLIT2,QKI,AHCTF1,NECTIN3,CLOCK,C2CD2,RBM39,NCOR2,LRIG1,ARHGEF10,SIPA1L1,SOCS5,FAM169A,PHF14,PUM1,DOCK4,GAPVD1,HDAC4,ZFYVE16,DAPK1,ZNF804A,SACS,DMD,MAMLD1,DNAJB6,E2F5,TSPAN5,YAF2,EGFR,VPS13B,ACSL4,TAOK3,DLC1,SEC24B,SUCO,FOXO3,PDLIM5,ATP6V1H,ATP2C1,STAU2,MPP6,FYN,SEPT9,AHDC1,MALT1,DBF4,ZNF638,FERMT2,ADGRA3,MAP4K5,AGFG1,RBPJ,KIF2A,MARK3,MBNL1,MEIS2,MIA2,MID1,MITF,MKLN1,AFF1,MN1,NEK1,CNOT4,SLC11A2,OPA1,PIK3C2A,CCSER2,STRN3,SCHIP1,PPM1B,PPP2R5E,PRKACB,ELOVL2,PTK2,PTPN13,PTX3,RDX,REV3L,ZC3H14,RPS6KA2,CLIP1,ATXN2,SEC14L1,SUPT20H,SCAF8,CHD9,FNDC3A,R3HDM2,WDR37,ABLIM3,LIMCH1,TMCC1,DOK5,KDM3A,ZHX3,MYCBP2,KDM4C,ERC1,CDK19,SPART,CLASP2,LARP4,ST5,NEK4,RGL1,ZC3H4,PRRC2C,SYNE2,VPS13A,ANKRD28,MTCL1,DNMBP,FAM208A,FBXW11,TBL1X,DMXL2,SATB2,ZEB1,TRIM2,TCF12,CLASP1,DOCK9,PUM2,FRYL,SIK3,DICER1,TIAM1,R3HDM1,PARD3,KAT6B,TP53BP1,TP53BP2,TRIO,SSBP2,HIRA,FAM155A,UBE3A,FLRT2,VLDLR,WRN,XPO1,XRCC4,INTS3,EVI5,NAV3,KAT6A,FXR1" Coexpression 17880687-TableS3 Human Embryo_Heim07_1515genes GeneSigDB 1.98E-17 2.25E-13 1.61E-14 1.59E-13 197 971 "NDRG2,TMEM132B,AXIN2,PCDH19,SPOP,MARCH4,SYT13,PDZD4,APBA2,APBB2,GAS7,PHYHD1,VAT1L,SHROOM2,CDC14B,IGDCC4,RASL11B,TMEM108,KIF1A,ADAM23,NRP2,PROM1,SYNJ1,SGCE,CALB1,THSD7A,PTBP2,RUNX1T1,CLDN10,DCLK1,LRRFIP1,CRLF1,CHN2,PLEKHB1,SLIT2,PPT2,FAM189A2,VAX2,ABCG2,HOMER3,CNR1,AKAP7,COL9A3,C2CD2,RBM39,SIPA1L1,CNTNAP2,CTH,HDAC9,MATR3,BRINP1,PITPNC1,LYPD1,GSDME,FAM107B,DYNC1I1,DPP6,DUSP9,DNM1L,EDN1,YAF2,FAM13A,EGFR,TMEM132E,EPB41,EPB41L2,RASGRP2,ERBB2,RASL12,TBC1D16,ACSL4,DLC1,OLFM1,AMOTL2,SEMA4D,FLNC,MPP6,MEGF10,GABBR1,GAD1,IQGAP2,CPLX2,IGSF5,GCNT2,PCDH17,GHR,GLI2,TOX3,KDM2B,GNAO1,GNG4,LNX1,PRUNE2,MCHR1,DIDO1,ATOH8,RASSF8,HAS2,TOX2,BACH2,IFI16,RBPJ,IL6ST,KCNN2,L1CAM,PAXBP1,SMAD9,AQP11,CHST6,SHC3,MEIS1,MEIS2,MID1,PPM1L,MPP2,TAGLN3,RTL5,NEFH,SETD4,OGG1,CDK18,PRTG,ENPP2,SLC10A4,GNG2,SNX10,ANKRD16,EPB41L4B,MINDY2,PPP1R1A,PTPRG,PTPRO,ZSCAN2,TTC13,RET,RFX3,RGS3,PRIMA1,RIC8B,MRAP2,BAALC,RPS6KA2,HUNK,CLIP1,MAPK12,SEMA6D,SATB1,PEAR1,MRAS,RASA3,ANKRD6,PREX2,FAM214B,KANSL3,SEPHS1,TET1,CPEB4,LIMCH1,SNRPN,PDZD2,SOX3,FNBP1,SPP1,PEG10,ARHGAP26,SPTAN1,TSPYL2,LMO3,SEPT3,KLHL7,SYNE2,RHBDL3,VPS13A,PDLIM2,KLHL4,WSCD1,TCF12,PCDHAC2,TEK,SLC44A1,TIAM1,LRRC8A,FAM124A,RGMB,TRIO,TRPS1,RPRM,FLRT2,CCDC136,VSNL1,RBFOX3,CLIP2,ZIC2,TMEM178A,RTN4,AP3B2,SPATA13" Coexpression 17880687-TableS1 Human Embryo_Heim07_1650genes GeneSigDB 5.90E-17 6.70E-13 4.46E-14 4.43E-13 218 1122 "ABHD6,NDRG2,FMNL2,TMEM132B,OLMALINC,ZNF608,PCDH19,TAOK1,SPARCL1,SPOP,PDZD4,APBB2,GAS7,VAT1L,EIF4G3,KIF1A,BACH1,SYNJ1,ARHGEF7,CASTOR3,SGCE,CA8,CACNA2D1,THSD7A,PTBP2,RUNX1T1,CBLN1,CLDN10,SCARB1,SEPT7,DCLK1,CRLF1,CHN2,PLEKHB1,B4GALT6,SLIT2,NRXN3,FAM189A2,ABCG2,HECTD1,HOMER3,CNR1,AKAP7,COL9A3,AHCTF1,RTTN,BAG4,FAM171B,C2CD2,SIPA1L1,PDE4DIP,CNTNAP2,FAM169A,HDAC9,TBC1D5,MATR3,DAPK1,BRINP1,YTHDC1,LYPD1,FAM107B,USP3,DYNC1I1,NR1D2,DPP6,DUSP9,EDN1,FEM1B,FCF1,KLHL5,YAF2,FAM13A,PHF20L1,EGFR,RGS17,EPB41,EPB41L2,ERBB2,SH3YL1,TBC1D16,ACSL4,DLC1,OLFM1,FHL1,POLK,FLNC,UFM1,GABBR1,GAD1,GCNT2,ARFIP1,PCDH17,GHR,GLI2,TOX3,TNRC6A,ZNF638,HTATSF1,GNG4,GPD2,PRUNE2,STON1,LPAR4,MCHR1,DIDO1,ATOH8,RASSF8,HAS2,UBE2QL1,TOX2,BACH2,MIER3,HNMT,IFI16,RBPJ,IL6ST,ZNF678,KCNN2,CAMK2N2,PAXBP1,SMAD9,MAP2,AQP11,MBNL1,CHST6,TM6SF1,MEIS1,MEIS2,MID1,MITF,MPP2,TAGLN3,RTL5,NEFH,CCDC13,CNOT4,SLC11A2,PRTG,ENPP2,GNG2,PIK3C2A,ZNF655,PLXNB1,PMP22,MINDY2,PPP1R1A,KANSL1,CEP41,PRODH,PTPRG,ZSCAN2,TTC13,USP47,RET,FIGN,RFX3,RGS4,RIC8B,EXD2,BAALC,SPIN3,HUNK,CLIP1,RYR3,AP1AR,MAPK12,SEMA6D,ATXN2,FNIP1,PEAR1,MRAS,TRA2B,FERMT1,CNKSR2,ANKRD6,PREX2,KANSL3,CCDC88A,CPEB4,GKAP1,LIMCH1,FAM126B,SOX3,FNBP1,SOX11,PEG10,TSPYL2,RBM26,LMO3,SOX21-AS1,SEPT8,SEPT3,PRRC2C,TMEM150C,FBXW11,KLHL4,WSCD1,ZMAT3,SLC44A1,TIAM1,LRRC8A,TP53BP1,RGMB,TRPS1,RPRM,FLRT2,VSNL1,RBFOX3,WIPF1,ZIC2,KCNT2,MAP3K12,STOX2,TMEM178A,RTN4,UBE3B,JMJD1C,NHSL1" Coexpression M10371 "Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells, as identified by ChIP on chip." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.69E-16 6.47E-12 3.87E-13 3.84E-12 214 1117 "ASIC1,GALNT16,ADCY8,LRFN2,SLC24A4,KLHL13,KIAA1324,ARHGAP20,AMPH,LRCH2,LGR5,SPTBN4,ZFYVE28,ARNTL,RGS20,PDE8B,CHRD,ATP1A3,TTLL9,ADAM15,ADGRB2,RGS9,ARHGEF7,CACNA1G,CACNA1A,CACNA1B,CACNB4,CAMK2B,CH25H,CBLN1,CD38,ENTPD2,DGKI,LRBA,DCLK1,CRLF1,CHN2,SLIT2,LHX2,RAB33A,VAX2,CNTFR,COL4A5,ANKRD35,NRG2,CNRIP1,CRMP1,SNCAIP,CSF1,RIMS4,PDE4DIP,RASGEF1C,DGKG,SV2B,SPOCK3,CHRDL1,DLX1,GRIN3A,HS3ST2,DYNC1I1,DPP6,DTNB,EBF1,CNNM1,HEYL,YAF2,EGR3,PLXNC1,TMEM132E,EPHB1,RAB9B,ERBB4,NRN1,FGF11,PRKAG2,HPCAL4,FOXF2,AGAP2,ZMYND15,PSD2,RASL10A,FUT9,TPPP3,B4GALNT1,SRRM4,PCDH17,GHR,NTNG2,DCLK2,RAB40B,GNAO1,PRUNE2,GPR12,STMN2,GRB10,GRIA2,PARD3B,GRIN2D,PTPRT,GSN,GUCY1A1,ATOH8,HBA1,PADI2,FRMD3,NEGR1,HSPA1L,SHISA6,SOWAHA,NIM1K,SCIN,LRRTM1,ITPKA,SLC35G1,KCNF1,GPR62,KCNK3,KCNQ3,CAMK2N2,MAP6,MAPT,MEIS1,ADAM22,MT1M,HS6ST3,LAYN,RTL5,FXYD7,NBL1,NEFM,NEFH,NFIX,NOVA2,NPTX1,NTRK2,PAX6,DPY19L2P2,PCDH8,PDE1B,SLC10A4,TMOD2,PLEC,PMP22,IRX1,PRKCB,MAPK4,DCHS2,CNNM2,ELOVL2,PTPRN2,SUSD4,RASGRF1,CRTAC1,DUSP15,EPHA10,RPS6KA2,STK32B,RYR3,SEMA6D,LRFN5,SMPD3,PPM1E,FRMPD1,SHC4,FAM81A,PKNOX2,SLC6A11,TRIM67,LGI3,GKAP1,PDZD2,UNC5B,SPTB,CLSTN2,MESP1,SSTR1,SSTR2,NKAIN2,PHLDB1,STX1A,ADAMTS17,ASTN2,TACR1,TAL1,ADGRL3,WSCD1,SATB2,SYNE1,CHST8,ARL10,HEY1,ICAM5,NR2E1,PRRT1,CSMD1,DOK6,ANKRD20A2,PRR18,OSBP2,FLRT2,WNT7A,KCNK12,ZIC1,TRIM9,REEP1,DPYSL5,LAMP5,SLC30A3,SLC30A4,SEMA3B,SLC17A7,KCNAB1,DPF3,ST8SIA2" Coexpression M2573 Genes consistently up-regulated in mammary stem cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.79E-16 6.58E-12 3.87E-13 3.84E-12 117 489 "PCDH19,OSBPL6,SRPX,ARHGAP20,LTBP4,LRCH2,PRX,ARNTL,ATP2A2,BACH1,MPDZ,NRP2,BMP7,DST,CACNB4,ARHGEF25,CRLF1,SLIT2,QKI,ABI3BP,CNRIP1,NECTIN3,CLIP3,VCAN,PPP1R16B,GPSM1,ARHGAP24,HDAC4,RUSC2,EDNRB,YAF2,EGFR,EGR3,EPHB1,RASL12,MRVI1,SCML2,FHL1,FLNC,PSD2,NSG1,CSDC2,MALT1,FERMT2,PTPRT,GSN,RNF165,BVES,HAS2,IL6ST,TTYH2,LIFR,MATN2,MBNL1,MEF2C,MEST,NBL1,ZC3H12B,ALDH1L2,NNAT,NPTX2,NRCAM,NTRK2,OXTR,PCDHGC3,ENPP2,PKD1,FAM216A,FXYD1,PCDH18,SCHIP1,SDK2,PPP2R2B,EPDR1,RELN,LAMA1,PTPRE,FAM184A,TSPY26P,RFX2,NUDT11,ARMH4,MEG3,KCNIP3,FHOD3,SLC4A3,LIMS2,PKNOX2,SLC6A8,SLC12A4,SNCA,SOX11,ZNF423,TSPYL2,THSD1,ELOVL4,STAC2,PHLDB1,NUDT10,ARC,TACC1,TCF4,TMEM121,TNS1,TPM2,ELP5,TRO,STXBP4,SSBP2,FLRT2,VSNL1,WIPF1,TRIM9,TMEM178A,PCBP4,MSRB3,NETO2" Coexpression M1951 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.75E-15 1.99E-11 1.06E-12 1.05E-11 116 490 "ABR,ACHE,ADRA1D,ADRA1B,ADRB2,HFM1,MARCH4,LTBP4,SYT13,DOC2A,ARHGDIG,ATP1A3,ADAM23,BMP7,CACNA1G,CACNA1B,CALB2,CH25H,ARHGEF25,CBS,USP2,MTMR7,SYNGR3,CRLF1,CHGB,ANKRD35,COL9A3,GDA,AATK,LRRC3B,PDE4DIP,PITPNM3,SPOCK2,BRINP1,ZNF804A,PLPPR4,DNM1,DYNC1I1,DPP6,RASGRP1,RCAN2,REEP2,OLFM1,FGF12,SEMA4D,FLNC,C2orf88,AK8,FAM49B,DLL3,HHIPL1,SRRM4,ACSS1,CPLX2,CYP46A1,MAP7D2,GNAL,GP1BB,CCDC184,TMEM121B,GRIK4,GRIN2D,SLC2A6,TNFAIP8L3,LRRC75A,IRF8,KIAA1755,INSM1,C2CD4C,ITPKA,KCNB1,KCNF1,CREG2,SMAD9,PIK3AP1,MATK,MBP,ADAM11,TM6SF1,SRSF12,MN1,NNAT,NPY,NPR2,NPTX2,KCTD15,NECAB2,FA2H,DIRAS2,ELOVL2,PTPRB,PTPRE,ZMAT4,DUSP15,RFX2,PRIMA1,LGI2,SNX22,PTGR2,RTN1,PEAR1,KIF16B,ABLIM3,SLC4A3,RADIL,ARC,SLC37A2,NSD1,SLC44A1,TPM1,KCNE5,OSBP2,MGAT5B,VIPR2,CELF4,PRDM8" Coexpression M2817 Genes up-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.76E-15 2.00E-11 1.06E-12 1.05E-11 63 195 "RALGAPA1,ACTN1,PCDH19,BIN1,OGT,ATP1A3,SLC4A4,CAMK2A,ZNF445,DLGAP2,NUMBL,SRSF11,CPNE6,NRXN3,CNR1,RBM39,TCAF1,SPOCK2,ZNF804A,ZC3H11A,DDX46,POM121,CD99L2,CPEB2,CNNM1,PLXNC1,SRRM1,DNAJC27,PTK2B,PPP1R1B,OLFM1,DOT1L,CPLX2,PRRC2B,RNF165,LINGO1,CREG2,MEF2C,NFIX,TMOD2,PIK3R1,SLC25A23,PPP2R2C,PPP2R5E,PRKAB2,MEG3,TNFRSF19,FNDC3A,SLC8A1,SMARCC2,SP4,MYCBP2,SYN2,TCF4,TRIM2,GPRIN3,NACC2,RIMBP2,R3HDM1,NR2C2,UBTF,RICTOR,SLC17A7" Coexpression 18338247-SuppTable4B Human Breast_Harvell08_428genes GeneSigDB 1.91E-15 2.17E-11 1.09E-12 1.08E-11 85 311 "NDRG2,PI16,PHYHD1,CDC14B,CDK10,ZFYVE28,ASPA,MARK4,DST,IL33,CAPN3,CDO1,FHL5,CNR1,ABI3BP,NRG2,NECTIN3,SLC35F1,PDE4DIP,CST3,PPP1R16B,PLCXD3,GREB1,BOC,HDAC9,GPRASP1,LONRF1,MATR3,CHRDL1,RAB39B,EDNRB,FAM13A,RASA4,ABCA8,FCGRT,OLFM1,FHL1,WDFY3-AS2,FAM107A,PADI2,AGFG1,ITGA7,KPNA5,SMAD9,MAP6,MATN2,SAMD5,BEX5,P2RY13,NOVA1,NTRK3,CLDN11,PDE1C,ENPP2,ABCB1,PIK3R1,PLCB2,FXYD1,LRRN3,PPP3CA,RELN,PTPRN2,REV3L,RGS12,KIRREL1,RTN1,LRFN5,SCN7A,CNKSR2,NLGN1,ARHGEF40,SNRPN,PLCB1,SYN2,TAL1,ADGRL3,PCDHGC5,SLC35G2,PRRT1,SYNPO2,ZNF781,GDPD5,NAV3,WNK3,DNAH10" Coexpression 16166618-SuppTable3 Mouse Lung_not_cancer_Woodruff05_2037genes GeneSigDB 5.53E-15 6.28E-11 2.99E-12 2.97E-11 237 1301 "ABHD6,FMNL2,TMCC3,ESYT2,ADRB2,BEND6,MTA3,KLHL13,AK2,ALCAM,MARCH4,AMPD3,ANK2,APBB2,CPNE5,CASK,TMEFF1,ARRB1,ARRB2,PDE8B,NCOA1,CHID1,ATP1A3,ATP6V0A1,KIF1A,DOCK11,NRP2,BID,PROM1,DST,RAB29,CACNA1A,KALRN,CAMK2G,CD86,SCARB1,CD38,AP4M1,ARHGEF2,CDC25B,LRRFIP1,CCPG1,LRWD1,CFL2,SOCS6,CHN2,MS4A7,B4GALT6,LHX2,FAM189A2,ABCG2,LY86,HOMER3,CNN3,FAM149A,AKAP5,SMARCAL1,CNRIP1,ENTPD4,ANKRD44,ABCG1,CSF1,SUSD5,PNPLA8,GREB1,USP6NL,CYBB,HDAC9,LONRF1,DGKG,DAPK1,GIT2,ARMCX2,YTHDC1,GSDME,DDX46,POM121,RHOBTB1,FAM107B,DMD,CDON,RCAN1,DTNA,EDN1,FEM1B,RASGRP1,KLHL5,FRY,OPTN,YAF2,RASA4,ENO2,VPS13B,COQ7,SLC43A2,DENND4A,SPEG,ETV1,CD320,NRN1,F5,FAM198B,ACSL4,PTK2B,CHST15,FCGRT,SPSB4,BAIAP2,ZMYND15,EVL,FOLR2,AK8,ATP6V1H,ATP2C1,GABBR1,B4GALNT1,IQGAP2,SEPT9,ACSS1,SESN1,GFRA2,LYVE1,LPAR4,GPR34,MUM1,RASSF8,ZHX1,ELOVL5,SYNPO,HNMT,IGF1,RBPJ,FAM69A,ITGAM,JAK2,KCNN3,KHK,STXBP5,L1CAM,LAMP2,LMO2,ASPRV1,SMAD1,PIK3AP1,GPR155,ZFYVE27,MATK,MATN2,MBP,MEF2C,MEIS1,ADAM22,MSR1,MYO5A,P2RY13,NFIX,NPY,NRCAM,P2RX7,P2RY1,TREM2,CDK18,PMP22,PILRA,PRKAR1B,PRKCB,SLC26A11,MASP1,SNRK,PTK2,SPDL1,NKAIN1,PID1,ZDHHC14,CCDC82,TMLHE,PCMTD2,ATP8B4,ST6GALNAC6,SEMA6D,RASA3,ST6GAL1,BTBD3,LIMS2,SLC6A8,SLC11A1,SLC12A2,LGI3,SLC22A4,KIF13A,FNBP1,SP4,UHRF1BP1L,MYCBP2,TEX2,ARHGAP26,LHPP,POGZ,NXT2,RGL1,STAC2,ADHFE1,SEPT3,SYNE2,SLC37A2,MCF2L,ALG1,ADGRL3,DMXL2,ZEB1,TRIM2,ARHGAP9,CYB561A3,ENHO,TIAM1,LRRC8A,FAM124A,CABIN1,TNS1,TPM1,NPL,TST,TTC3,SGK3,FLRT2,LAT2,TCEAL7,CELF4,AMZ1,SPIRE1,SLC30A4,KCNAB1,FIP1L1,PLD4,RGS7BP,DOCK8,PHTF2" Coexpression M9898 Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [GeneID=23512] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.03E-15 6.85E-11 3.11E-12 3.09E-11 199 1038 "DGCR6,ABHD6,ADCY8,PTCHD1,SLC24A4,KIAA1324,ARHGAP20,LRCH2,LCORL,GAS7,LGR5,ZFYVE28,RGS20,PDE8B,CHRD,ADGRB2,ARHGEF7,CACNA1G,CACNA1A,CACNA1B,CACNB4,HAP1,CH25H,CBLN1,CD38,DGKI,NOG,CRLF1,SLIT2,LHX2,RAB33A,VAX2,CNTFR,COL4A5,NRG2,CNRIP1,CRHBP,CRMP1,GDA,CSF1,LRRC3B,PDE4DIP,SLITRK5,DGKG,SPOCK2,LYPD1,PLPPR4,SV2B,SPOCK3,DLX1,GRIN3A,HS3ST2,USP3,DPP6,EDN3,CNNM1,RASGRP1,EGR3,TMEM132E,KCTD3,EMX2,EPHB1,RAB9B,ERBB4,DLC1,ST3GAL6,FGF13,TMEM164,HPCAL4,ZMYND15,AFF2,RASL10A,TPPP3,MEGF11,B4GALNT1,ACSS1,GATM,ALDH1L1,TUBA8,GFRA2,PCDH17,GHR,NTNG2,MAP7D2,DCLK2,RAB40B,GPR12,STMN2,GRIA2,GRIN2D,PTPRT,SOX21,GUCY1A1,ATOH8,HBA1,TOX2,FRMD3,HLF,TCEAL6,SHISA6,NKD1,INSM1,LRRTM1,ITPKA,ITPKB,KCNJ5,KCNQ3,SYTL4,MAP6,MAPT,MID1,MT1M,HS6ST3,LAYN,NEXMIF,NBL1,NDP,NEFM,NEFH,NFIX,NPTX1,NRCAM,NTRK2,NTRK3,PAX6,DPY19L2P2,PCDH8,SLC10A4,TMOD2,PLEC,PMP22,TRHDE,IRX1,MAPK4,DCHS2,EML5,RIPOR1,TMEM255A,SUSD4,RASGRF1,RASGRF2,CRTAC1,RORB,EPHA10,STK32B,RYR3,SEMA6D,LRFN5,SCP2,HSPA4L,PPM1E,FRMPD1,SHC4,ST8SIA1,FAM81A,PKNOX2,SLC6A11,TRIM67,LGI3,PDZD2,SOX3,UNC5B,SPTB,CLSTN2,MESP1,THSD1,SSTR1,SSTR2,PHLDB1,PLCB1,ASTN2,TACR1,TAL1,ADGRL3,TBL1X,CHST8,HEY1,ICAM5,CSMD1,PARD3,DOK6,ANKRD20A2,FLRT2,MGAT5B,VIPR2,WNT7A,KCNK12,ZIC1,ZNF711,TRIM9,DPYSL5,LAMP5,SLC30A3,SLC30A4,KCNAB1,ADAMTSL3,KLHDC1,DPF3,ST8SIA2" Coexpression 17555561-Table2 Human Breast_Mackay07_1395GenesUpRegulated GeneSigDB 1.06E-14 1.21E-10 5.25E-12 5.21E-11 221 1196 "CLK4,BEND6,OSBPL8,TAOK1,C1QTNF3,SPARCL1,SRPX,GPRASP2,AMPD3,OGT,KCNAB2,APBB2,APC,UPRT,SFMBT2,CASK,ARNTL,DNAH17,CCAR2,DOCK11,BBS2,NRP2,CFLAR,KSR1,ST3GAL5,BTK,CA4,CACNB4,THSD7A,LDB2,SYNGR3,SEPT7,ZMYM4,LRRFIP1,CFL2,RCBTB2,CHN2,CNOT8,RAB33A,RAB28,TPP1,QKI,LY86,AKAP7,COL9A3,AKAP5,MYRIP,ZNF521,FAM171B,SEC31B,AKAP12,SNCAIP,ARHGEF10,OSBPL3,VCAN,SOCS5,PDE4DIP,RASGEF1C,CYBB,DOCK4,HDAC4,MATR3,DAPK1,HEPH,ELMO1,WDR20,DNAH9,DOCK2,DPYSL2,ECM2,GOLT1B,AASDH,EDNRA,EDNRB,FAM13A,ASB3,ELN,STARD3NL,CALCRL,PAN3,RCAN2,STX2,DNAJC27,TLR7,SEC24B,FER,SYNCRIP,FOXO3,PDLIM5,FAM49B,OGA,FYB1,GALNT15,TRAF3IP2,GALC,RAPGEF6,IQGAP2,GCK,ARFIP1,WASHC2A,SESN1,GGTA1P,MALT1,LYVE1,TCERG1,SPIN1,LNX1,GPR34,DIDO1,GUCY1A1,VSIG4,IRF8,SCIN,IL6ST,JAK2,KCNF1,STXBP5,LAMP2,MBNL1,MBP,MEIS2,KITLG,MID1,MKLN1,AFF1,MMP16,BLOC1S2,MYO5A,MYO9A,NDP,NEK1,SLC11A2,PIK3R1,RETREG1,PCDH18,PPARA,PPP3CC,PRKAB2,MAPK10,LAMA1,MTMR10,ELOVL2,ZSCAN32,PEX2,PPP2R3C,FAT4,HKR1,REV3L,GTDC1,KLHL11,RNASEL,RNH1,RPL15,SATB1,PEAR1,GALNT10,SGK1,FNDC3A,ST6GAL1,PREX2,SLC8A1,CCDC88A,RCOR3,TTC17,IFT122,FAIM2,TMCC1,PDZRN3,SPATA7,KDM3A,GLT8D1,MYCBP2,KDM4C,ZNF423,ARHGAP26,CLASP2,ZNF302,ZC4H2,SEPT8,RGL1,KLHL7,PRRC2C,PLCB1,SYPL1,TACC1,MCF2L,AGTPBP1,TCEA1,WSCD1,TCF4,ZEB1,TRIM2,TCF12,SYNE1,PUM2,CRTC1,SIK3,DICER1,SIRT1,KHDC1,AP4E1,ZMAT3,ZNF106,SLC44A1,TLR4,PIK3R5,TP53BP2,SYNPO2,TSC1,SSBP2,UBE3A,PLEKHH2,ZNF24,TCEAL7,ZFAND5,SMARCAD1,ADAMTS9,JMJD1C,FRMD6,RNF146,LAS1L" Coexpression 17660535-TableS4b Mouse InnerEar_Sajan08_2230genes GeneSigDB 5.39E-14 6.13E-10 2.55E-11 2.53E-10 322 1948 "DGCR6,ABCF1,NDRG2,ADD1,ADD2,AXIN2,AP2A1,OSBPL1A,SPARCL1,SPOP,ARHGAP20,AMPH,OGT,FGD2,PKP4,APBB2,APLP1,SEMA4G,PRX,ARNTL,ARRB1,RASL11B,MYOM1,RIPK1,SEC11C,RGS9,NRP2,ST3GAL5,FUBP1,MTMR3,RAB29,DDR1,CACNA2D1,HAP1,CAMK2G,HIP1R,CBLN1,CBR1,CLDN10,CCNH,USP2,SCARB1,LRBA,CDH2,ZMYM4,LARGE1,LRWD1,CRLF1,CACNA2D2,PLEKHB1,RAB33A,CLCN3,MAP4K4,LETMD1,COL9A3,IGDCC3,NECTIN3,PREPL,AKAP12,HAPLN1,RNF14,HINFP,NCOR1,CRYM,SEC24C,LRIG1,ARHGEF10,VCAN,PDE4DIP,GREB1,PUM1,RIMS2,GPSM1,MYADM,AIF1L,DBN1,PITPNC1,MYEF2,C2CD2L,DDX46,SNAP91,PARD6A,FAM107B,DLX1,DYNC1I1,SLC12A6,PDCD6IP,DUSP9,HIPK3,EEF1D,APH1A,EGFR,KMT5B,AASS,EIF4G1,EIF5,COPS4,STARD3NL,RCAN2,RASL12,ADGRV1,EZH1,ARMCX1,ACSL4,PTK2B,TAOK3,SCML2,PRMT5,GTF2IRD2,POLR1B,FGF13,FGFR1,SCARA3,UBE2E3,PCYOX1,SEMA4D,ANKFY1,NOP56,FLYWCH1,NELFCD,COQ5,PDLIM5,KHDRBS3,FUT9,SARAF,FYN,GAA,CHL1,TRAF3IP2,B4GALNT1,MTHFD2,INPP5K,NEU3,GCNT2,GFER,USP19,GHR,DHRS4,CRCP,TCERG1,RNPS1,TNRC6A,GPT2,GP1BB,GRIA2,GRM8,GSN,GSTM5,GSTT2,SOX21,PSIP1,MAP4K5,ZHX1,FRMD5,AGBL5,HNMT,ICA1,MSL1,IDH3A,NKD1,LRRTM1,KCND2,KTN1,LAMP2,PAXBP1,ZFYVE27,MARK1,MAT2A,MATK,MBNL1,MEIS1,MEIS2,MEST,MITF,MKLN1,AFF1,NRBP2,NRCAM,NTRK2,NTRK3,NUCB2,PCSK5,PDCD2,PDE4B,ENPP2,ZDHHC8,SEMA5B,SNX10,PKM,PLCD1,STRN3,EXOSC10,POLR2F,IRX1,PPM1B,PPP2R2B,MAPK3,GDPD1,MASP1,BCAS3,PSMA6,LAMA1,QRICH1,PTCH1,ANKHD1,MTMR10,PTN,PTPRD,EML5,PTPRE,TTC13,PPP2R3C,SUSD4,RAP1GDS1,OXR1,RASGRF1,RBBP6,ZDHHC14,REV3L,ZDHHC4,RGS3,RNASEL,ZFHX4,RNH1,ELP2,PCMTD2,EMID1,RTN1,RXRA,S100B,SAFB,SARS,SATB1,TNFRSF19,SEC14L1,GALNT10,PUF60,SCAF8,SH3BGR,FAM102A,FNDC3A,FHOD3,SLC2A5,LIMS2,SLC6A8,CCDC88A,SLC11A1,SLC12A2,ATF7IP,ZKSCAN3,SMARCA4,SMARCD3,LIMCH1,SNCA,SNRPN,USP33,FNBP1,SOX11,KDM3A,SP4,MYCBP2,SPP1,ERC1,CAMTA2,ERBIN,MPRIP,PHLDB1,SULF2,NSFL1C,JMJD6,PDLIM2,TCF4,ZFP90,CUX2,TRIM2,TCF12,OBSL1,PUM2,ZMAT3,THRA,TMEM9,NACC2,HEY1,CBX5,BEX4,ANKRD24,PRRT1,PARD3,TPM1,TRIO,TRPS1,RUSC1,SSBP2,HSPBP1,TTC3,HIRA,UBC,UBE3A,UCHL1,MTCH1,PCDH20,ZFP37,ZBTB14,SPHK2,CELF4,SH3GLB2,ZFAND5,SMARCAD1,SLC30A4,MAP3K12,CIAPIN1,SEMA3B,ITM2C,PCBP4,WNK2,ST7,HNRNPA3,PHTF2,JMJD1C,RNF146,AP3B2,SPATA13" Coexpression 16849537-SuppTable2 Human StemCell_Davicioni06_534genes GeneSigDB 1.20E-13 1.36E-09 5.45E-11 5.41E-10 113 500 "LTBP4,ALK,AMPD2,ANK2,PKP4,CDC14B,MARCH3,NCOA1,DST,CACNA1G,DDR1,PTBP2,CCNH,ARHGEF2,DLGAP2,RAB28,CLCN3,CNR1,CRMP1,ABCG1,SNCAIP,DZIP3,ARHGEF4,RIPOR2,DAPK1,BRINP1,JAKMIP2,ELMO1,FBXL5,MAMLD1,EDN3,EEF1D,FRY,EGFR,RGS17,ERBB2,PIPOX,NRN1,DLC1,SCARA3,SYNCRIP,IQCG,DENND2A,DISC1,SESN1,TOX3,PRRC2B,ACOT7,HSF2,RBPJ,FAM69A,KCNN3,LAMA2,TAGLN3,MYCN,NF1,NNAT,NRCAM,NTRK3,PMP22,MINDY2,PPP3CA,PTH1R,ELOVL2,PTN,PTPN13,PTPRD,NKAIN1,QDPR,FAT4,ROGDI,ERI2,MORC4,NUDT11,ZFHX4,CCDC25,CLIP1,RYR3,CSRNP3,FRMPD1,ASAP3,ARHGEF40,PDZRN3,KDM4C,TEX2,ARHGAP26,CLASP2,CEP68,RGL1,KANK1,SYNE2,SYN2,COBL,ASTN2,DNMBP,AGTPBP1,WSCD1,SATB2,DOCK9,OBSL1,FRYL,HIF3A,CHST8,AKTIP,HEY1,TRPS1,BCL2L13,VIPR2,ZIC1,SLC38A1,SEMA3B,NAV3,ITM2C" Coexpression 18535662-TableS2a Mouse Lymphoma_Wu08_1777genes GeneSigDB 3.37E-13 3.83E-09 1.47E-10 1.46E-09 172 894 "CLK4,AP2A2,TAOK1,C1QTNF3,ALCAM,OGT,MYH7B,PHYHD1,CASK,ASGR1,CHID1,ATP1B3,ATP6V0A1,ADAM15,BACH1,NRP2,BID,SYNJ2,BTK,SGCE,CACNA1G,CACNA1B,CALM1,CAMK2G,CAST,SPAG9,RUNX1T1,ARHGEF25,CBFA2T2,CDH2,CDO1,FOXN3,CNOT8,TPP1,ABCG2,TMEM184B,PICK1,IQCK,SUMF2,COL11A2,MAGED1,CREM,ENTPD4,CRMP1,CLIP3,ARHGEF10,SIPA1L1,GPSM1,BOC,IP6K1,DBN1,PITPNC1,NR1D2,TOM1,GOLT1B,KLHL5,ASB3,ELN,SLC43A2,STX2,ERBB2,NCALD,VPS26C,EXTL2,EZH1,RPS6KC1,RACK1,FCGRT,FDFT1,FECH,FGFR1,BAIAP2,FHL1,FLNC,FLT1,DCTN2,ATP6V1H,ERGIC3,CGREF1,SARAF,ABLIM2,INPP5K,DHRS4,FERMT2,PRUNE2,GSN,MAP4K5,JAK2,METTL21A,KIF2A,LAMP2,LIFR,MAT2A,MEST,PPM1L,MMP16,NRBP2,TAGLN3,NBL1,NFE2L2,NUCB2,RETREG1,PLCD1,PLTP,MAPKAP1,SH3KBP1,PPM1B,PPP3CA,PPP3CC,EPDR1,RELN,CNNM2,APTX,PTH1R,PTPN13,RAD17,RDX,TRIM68,PCMTD2,CLIP1,SARS,TNFRSF19,COPZ1,RASA3,PUF60,CHD9,FNDC3A,ARHGEF40,CDK5RAP3,KBTBD4,ABTB1,IFT122,LIMCH1,LMBRD1,GLT8D1,SPP1,ERC1,SPART,STAU1,SEPT8,PHLDB1,SYP,ANKRD12,SMG6,PCDHGA11,OBSL1,FRYL,CYB561A3,SLC44A1,TMEM9,TK2,TRIO,PDSS1,UBC,TOM1L2,VLDLR,TBC1D15,WIPF1,ATP6V0E2,POLR3H,MEIS3,NT5M,EVI5,STOX2,NAV3,DOCK8,MARCH8,MSRB3,ZDHHC20,FXR1,NETO2,SPATA13" Coexpression 19808870-ST1 Human Breast_Speers09_780genes GeneSigDB 4.50E-13 5.12E-09 1.90E-10 1.88E-09 152 762 "CLK4,ADRA1B,ADRB2,NME5,AK2,TAOK1,MARCH4,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2G,DGKI,DCLK1,EVI5L,COPB2,TAOK2,MAP4K4,PICK1,AKAP7,AKAP6,AKAP5,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,SOCS5,PITPNM3,APPL1,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DMPK,RPS6KL1,HIPK3,EGFR,TNK2,SRPK3,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,PPP1R1B,FER,FGFR1,FGFR3,IP6K2,FLT1,AKAP3,NBEA,CINP,AK8,PDLIM5,TPK1,CAMKK2,BRSK1,FYB1,FYN,IP6K3,GCK,GFRA2,MALT1,TTBK1,DBF4,DCLK2,CIT,PTPRT,MAP4K5,IRAK3,MYLK2,ITPKA,ITPKB,JAK2,KHK,KIT,MARK1,MARK3,MATK,MPP2,NRBP2,NEK1,NME4,NPR2,NTRK2,NTRK3,KSR2,CDK18,PDPK1,PFKFB2,PFKFB3,PFKFB4,PIK3C2A,PKM,EXOSC10,PRKACB,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PRPSAP2,SNRK,PTK2,STK32A,PTPRG,RASGRF2,RET,RNASEL,NEK11,RPS6KA2,STK32B,HUNK,MAPK12,SGK1,SEPHS1,CDK5RAP3,MAST1,CDK19,NEK4,TTBK2,SIK3,TEK,TK2,TLR4,CDK20,TRIO,SGK3,SPHK2,MAP3K12,WNK3,WNK2" Coexpression 19658189-TableS3 Human EmbryonicStemCell_Xu09_1311genes GeneSigDB 6.32E-13 7.17E-09 2.56E-10 2.54E-09 182 969 "DGCR6,NDRG2,ADCY5,ADCY6,ADORA1,RNF150,ADRB2,MTUS1,KLHL13,AGT,NME5,ANK2,PPFIA4,CPNE5,CDK10,PLA2G4C,CADPS,MARK4,ATP1A1,SLC4A4,ATP2A2,SLC2A11,ATP6V1G2,MYOM1,ADGRB2,RGS9,GPR146,BMP7,SYNJ1,JAZF1,CACNA1G,KALRN,CAMK2A,CAMK2B,CAPN3,CAST,USP2,RGN,ENTPD2,DGKI,CDH2,L3MBTL4,MAGI1,QKI,AKAP6,COL9A1,CRHBP,CRY2,RNF14,CSNK1E,PHACTR3,HDAC9,ARHGAP24,ZFYVE16,HEPH,KIAA0319,KLHL3,SNAP91,DMD,DMPK,NR1D2,CPEB2,DTNA,ABCC5,EDNRA,FRY,YAF2,PHF20L1,TNK2,RAB9B,RRAGB,KATNAL1,ABCA8,DLC1,ST3GAL6,FECH,PRKAG2,FLNC,FOLR2,PDLIM5,GATM,GCK,ADAM28,FREM1,PPARGC1A,BRD8,DCLK2,GNAL,GNAO1,GP1BB,PLPP7,GRM8,BTN2A1,BVES,ATOH8,FRMD5,FRMD3,HSPA1L,ICA1,IDH3A,ZNF181,IL6ST,JAK2,KCNH2,KCNJ5,KPNA5,KTN1,LAMA2,HECTD2,SMAD9,MAP4,MARK1,MBNL1,ADAM11,TM6SF1,MEF2C,MEIS1,MEIS2,MITF,PDE4D,PFKFB2,PGAM2,DUSP26,PLCL1,FXYD1,SCHIP1,MAPK4,MASP1,PTPRE,TMEM255A,ZCWPW1,RBBP6,ZNF568,SCN2B,MRAS,SUPT20H,SH3BGR,SH3GL3,CPEB3,MYO18A,FHOD3,SLA,SLC4A3,FAM81A,LIMS2,SLC8A1,CPEB4,SMARCD3,SNCA,UNC5B,ARHGAP26,SPTB,LMO3,DIP2A,VPS13A,PDLIM2,KLHL4,DOCK9,PCDHB10,PCDHB7,TPM1,TPM2,SYNPO2,OSBP2,VIPR2,PCDH20,ZNF32,ZNF540,NDRG4,ZNF154,REEP1,SLC30A3,PRDM8,RNF103,PPP1R3F,MPPE1,EPM2A,HRASLS,ST7,PHTF2,MSRB3,DPF3" Coexpression M4960 Genes down-regulated in basal subtype of breast cancer samles. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.14E-13 9.24E-09 3.19E-10 3.16E-09 142 701 "C3orf14,MTUS1,NME5,KIAA1324,C1QTNF3,SPARCL1,ALCAM,APBB2,DDO,BCAS1,ASPA,ZSCAN18,CHRD,AZGP1,ADGRB2,RGS11,BMPR1B,BAIAP3,IL33,LDLRAD4,CA12,CAMK2B,RHBDL1,LRBA,DCLK1,CLGN,CACNA2D2,CHN2,RAB26,CNR1,COL4A5,SLC4A8,CRY2,ABCG1,LRIG1,CNTNAP2,CST3,DZIP3,KIAA0040,GREB1,FAM131B,ARHGAP32,SNPH,C2CD2L,FRY,EGR3,KCTD3,COQ7,LRRC17,ERBB2,ERBB4,ABCA8,FAM198B,ZMYND10,FGFR1,FGFR3,EVL,EFCAB2,NBEA,STAU2,TPPP3,IQGAP2,HIGD1B,SYT17,SRCAP,TOX3,STARD3,GPD1,PCLO,GRIA2,PTPRT,GSTT2,ELOVL5,HNMT,ICA1,MSL1,IGF1,IL6ST,ITGA7,MAPT,MATN3,MMP17,MYO6,MYT1,NELL2,NF1,NOVA1,NTRK2,NUCB2,TREM2,PCSK5,SERPINI1,RETREG1,PLCL1,PLIN1,PLXNB1,LRRN3,PRKACB,ELOVL2,PTPRN2,ACSM5,NKAIN1,QDPR,TRIM68,RET,STK32B,RTN1,DGLUCY,SMPD3,GALNT10,KIF16B,SYBU,ABLIM3,CXXC4,IFT122,FAIM2,KDM4B,SPATA7,PBLD,CLSTN2,SSTR2,SEPT8,SYT1,ASTN2,MCF2L,EXOC7,DNMBP,TIMP4,TK2,KAT6B,LMF1,NPDC1,XRCC4,SPHK2,REEP1,LAMP5,MAP3K12,DNALI1,SLC38A1,SEMA3B,NAV3,KCNAB1" Coexpression M1712 Genes enriched in neurons in the adult mouse brain identified through correlation-based searches seeded with neuron cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.38E-12 1.56E-08 5.22E-10 5.17E-09 31 69 "ADD2,ALCAM,MADD,ATP6V1G2,CAMK2A,CAMK2B,SYNGR3,CHGB,CHN1,TCAF1,DPP6,FLYWCH1,CPLX1,GPR162,GRIA2,DISP2,MYO5A,JAKMIP1,PRKAR1B,PTPRN,MEG3,RTN1,NAPB,SNAP25,FAIM2,SNRPN,SYP,SYT1,PHF24,UCHL1,NDRG4" Coexpression 19168792-TableS3 Human Leukemia_Figueroa09_1035genes GeneSigDB 1.63E-12 1.85E-08 5.96E-10 5.91E-09 152 774 "ADCY8,PTCHD1,HECW2,KCTD16,OSBPL1A,C1QTNF3,CDC42BPA,LGR5,SPTBN4,CADPS,ZNF582,NRP2,BMP7,ARHGEF7,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,KALRN,L3MBTL4,MAGI1,CDO1,CHGB,CNN3,ZFP28,HAPLN1,C1QL2,SNCAIP,RGS6,SUSD5,GALNT9,VCAN,PITPNM3,PYGO1,KIF26A,MATR3,PABPC5,ZNF804A,LYPD1,GRIN3A,TMTC1,CELSR3,ZNF549,ETV1,NRN1,TAOK3,CEP78,FECH,UBE2E3,FUT9,CHL1,GABRB3,B4GALNT1,SYT17,CPLX2,PCDH17,PPARGC1A,MALT1,MAP7D2,PRUNE2,STMN2,GRIA2,PTPRT,RNF165,SOX21,GUCY1B1,IRAK3,FRMD3,MIER3,HLF,SMAP1,IRF8,SOWAHA,ZIC5,INSM1,LRRTM1,KCNN2,KCNQ3,KTN1,MAP6,MARK1,CHST6,MYO7A,NDP,NEFM,NOVA1,NRCAM,OXTR,PCDH8,GPR173,PCDH18,PSAT1,PPP1R1A,PCDHB17P,PPP2R2C,DIRAS2,RELN,ELOVL2,PTPN13,PTPRO,SH3TC2,RASGRF1,HKR1,PRIMA1,RNH1,SALL1,LRFN5,SCP2,SUPT20H,HSPA4L,DZIP1,FAM81A,SLC6A11,TRIM67,ZNF667,OGDHL,PDZRN3,SOX3,SOX11,DOK5,HECW1,PEG10,SSTR1,SYNE2,RHBDL3,SATB2,PCDHGC5,PCDHGB7,PCDHB15,PCDHB10,PCDHB6,TPM1,DOK6,RGMB,RUSC1,TSN,CA14,PRR18,FLRT2,PLEKHH2,KCNK12,PCDH20,ZNF540,NDRG4,SPIRE1,ZNF225,ADAMTS9,WNK3,WNK2,HRASLS,MSRB3,AP3B2" Coexpression M2012 Genes up-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.96E-12 2.23E-08 6.97E-10 6.91E-09 82 331 "ALK,ANK2,PKP4,CDC14B,ARRB1,MARCH3,NCOA1,DST,DDR1,PTBP2,CCNH,ARHGEF2,DLGAP2,RAB28,CLCN3,CNR1,CRMP1,ABCG1,DZIP3,ARHGEF4,RIPOR2,DAPK1,BRINP1,JAKMIP2,ELMO1,FBXL5,MAMLD1,EDN3,FRY,RGS17,PIPOX,NRN1,SYNCRIP,IQCG,SESN1,TOX3,PRRC2B,ACOT7,HSF2,RBPJ,FAM69A,KCNN3,TAGLN3,MYCN,NF1,NRCAM,NTRK3,PPP3CA,ELOVL2,TMEM260,PTPRD,NKAIN1,QDPR,ROGDI,ERI2,MORC4,NUDT11,CLIP1,RYR3,FRMPD1,PDZRN3,KDM4C,TEX2,ARHGAP26,CLASP2,CEP68,KANK1,SYNE2,SYN2,COBL,ASTN2,DNMBP,AGTPBP1,WSCD1,SATB2,DOCK9,FRYL,CHST8,AKTIP,BCL2L13,VIPR2,SLC38A1" Coexpression M13522 "Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.05E-12 2.32E-08 7.04E-10 6.98E-09 107 483 "OSBPL8,SPOP,OGT,CDC42BPA,PKP4,PARG,CASK,RGS20,CDK13,NCOA1,NUMB,EIF4G3,BARD1,BLM,DST,ARHGEF7,FUBP1,KRIT1,USP6,ZMYM4,FOXN3,QKI,CLOCK,C2CD2,RBM39,NCOR2,SOCS5,FAM169A,PUM1,GAPVD1,DAPK1,ZNF804A,MAMLD1,TSPAN5,EGFR,DLC1,SEC24B,FOXO3,STAU2,MPP6,FYN,SEPT9,ZNF638,FERMT2,MAP4K5,RBPJ,KIF2A,MARK3,MBNL1,MEIS2,MID1,MKLN1,AFF1,CNOT4,OPA1,CCSER2,STRN3,SCHIP1,PPM1B,PPP2R5E,PRKACB,PTK2,REV3L,CLIP1,ATXN2,SEC14L1,SCAF8,CHD9,FNDC3A,R3HDM2,LIMCH1,ZHX3,MYCBP2,CLASP2,LARP4,ZC3H4,PRRC2C,VPS13A,MTCL1,DNMBP,FAM208A,FBXW11,TBL1X,SATB2,ZEB1,TRIM2,TCF12,CLASP1,PUM2,FRYL,SIK3,TIAM1,R3HDM1,PARD3,KAT6B,TP53BP2,TRIO,HIRA,UBE3A,FLRT2,WRN,XPO1,XRCC4,USP32P2,EVI5,KAT6A,FXR1" Coexpression 16166618-SuppTable4 Mouse Lung_not_cancer_Woodruff05_2371genes GeneSigDB 2.23E-12 2.53E-08 7.43E-10 7.37E-09 255 1505 "ABR,ABHD6,AS3MT,ACTN1,FMNL2,TMCC3,MTA3,OSBPL8,ALCAM,ABCD2,MARCH4,BIN1,OGT,FGD2,LCORL,APBB2,GAS7,BCAS1,CPNE5,ARRB1,ARRB2,PDE8B,NCOA1,CHID1,DPY19L3,ATP6V0A1,ADAM23,BID,DST,ST3GAL5,RAB29,CACNB4,KALRN,CAMK2G,CH25H,PRC1,METTL6,USP2,MTMR7,CD86,SCARB1,CD38,ARHGEF2,CDC25B,LRRFIP1,CDO1,CCPG1,CFL2,SOCS6,MS4A7,B4GALT6,FAM189A2,CNN3,AKAP7,ARMC8,FAM149A,AKAP5,MAGED1,CREM,RNF14,ANKRD44,NCOR2,GDA,ABCG1,CSF1,CSNK1E,OSBPL3,SIPA1L1,SOCS5,PDE4DIP,PNPLA8,GREB1,USP6NL,DOCK4,HDAC9,RIPOR2,LONRF1,DGKG,DAPK1,DBI,GIT2,ARMCX2,GSDME,DDX46,POM121,RHOBTB1,FAM107B,DMD,CDON,RCAN1,DUSP9,E2F5,TSPAN5,RASGRP1,FRY,OPTN,YAF2,EBI3,PLXNC1,RASA4,CALCRL,DCTN4,ENO2,ENPP6,SPEG,ETV1,F5,FAM198B,ACSL4,PTK2B,CORO2B,CHST15,FCGRT,GORAB,FGF11,SPSB4,FGFR1,BAIAP2,PCYOX1,EVL,FLT1,FOLR2,SMC2,SPECC1,HVCN1,AK8,ATP6V1H,FYB1,B4GALNT1,RAPGEF6,IQGAP2,MTHFD2,SEPT9,ACSS1,GCNT2,SESN1,GGT5,HPGDS,DBF4,GLUL,GPT2,PRRC2B,LPAR4,DIDO1,MUM1,IRAK3,RASSF8,HNMT,IGF1,RBPJ,FAM69A,ITGAM,KCNN3,KIT,STXBP5,L1CAM,LAMP2,LIFR,LIMS1,HECTD2,SMAD1,PIK3AP1,GPR155,MATK,MATN2,MEIS1,AFDN,MN1,ADAM22,MSR1,MYO5A,MYO6,P2RY13,NFIX,NPY,NUCB2,P2RY1,TREM2,CDK18,GNG2,PFKFB4,SNX10,PMP22,PILRA,SH3KBP1,PRKAR1B,PRKCB,GRAMD1C,SNRK,MTMR10,PTK2,PTPRO,NKAIN1,PID1,ZDHHC14,CCDC82,SARS,SEMA6D,SATB1,MRAS,HSPA4L,CHD9,ST6GAL1,BTBD3,LIMS2,SLC6A8,SLC11A1,SLC12A2,SLC22A4,SMARCC2,IFT122,KIF13A,TMCC1,FNBP1,SP4,UHRF1BP1L,MYCBP2,SPP1,ARHGAP26,DBNDD2,SPART,RGL1,STAC2,SULF2,SEPT3,ZC3H4,SYNE2,SYN1,SLC37A2,MCF2L,ADGRL3,DMXL2,ARHGAP9,SIK3,CYB561A3,ENHO,TIAM1,BHLHB9,LRRC8A,TMPO,PRRT1,TNS1,AMACR,TTC3,TUBB2A,FLRT2,LAT2,AGMO,CELF4,AMZ1,SPIRE1,TUBA1A,RTN4,PHTF2,ZDHHC20" Coexpression M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.29E-12 2.60E-08 7.43E-10 7.37E-09 98 428 "EMILIN3,GALNT16,KIAA1211,LRFN2,SPARCL1,PCDH10,SYT13,AMPH,DPP10,PKP4,FAM131A,IGDCC4,ADAM23,ADGRB2,NRP2,CACNA1G,WASF1,RUNX1T1,LDB2,CBFA2T2,CDH2,LARGE1,MS4A7,CHRNA4,SLIT2,CNTN1,AKAP5,ZNF521,FAM171B,ENTPD4,NCOR2,PDE4DIP,DOCK4,GPRASP1,HDAC4,RASSF2,ARMCX2,TIAM2,FAM107B,GRIN3A,EDIL3,EDNRA,FEM1B,FAM13A,TMEM132E,ELN,C8orf37,EPHB1,TMEM132C,MEX3B,NBEA,CAMKK2,ABLIM2,DENND2A,AHDC1,GUCY1A1,GUCY1B1,MAP4K5,NEGR1,IGF1,RBPJ,KNDC1,PACRG,MARK1,MATN2,MBD1,MEIS1,MMP16,SAMD5,MYCN,NFIX,NTRK2,PRTG,PDE1B,ENPP2,SEMA5B,PCDH18,SH3KBP1,PRKCB,ZMAT4,REV3L,ROBO2,HUNK,LRFN5,ANKRD6,SLC14A1,ERC1,LHPP,LMO3,RHBDL3,ADGRL3,TCF4,SYNPO2,TSN,WNT7A,PCDH20,KCNAB1,NETO1" Coexpression M2892 Genes up-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 3.24E-12 3.68E-08 1.02E-09 1.01E-08 47 143 "NME5,SPARCL1,ANK2,ASPA,CALB1,DLGAP2,CDR1,CHGB,CRYM,ERC2,SNAP91,SV2B,DYNC1I1,RCAN2,ETV1,NRN1,ST3GAL6,HPCAL4,NSG1,GAD1,GATM,GPR37,GRIA2,KIT,MEF2C,NRCAM,PCDH9,SERPINI1,PLCL1,RELN,NUDT11,RTN1,SATB1,CPEB3,LIMCH1,SNAP25,NMNAT2,LMO3,PLCB1,SYT1,WSCD1,TRIM2,HEY1,VIPR2,TRIM9,PLSCR4,FZD3" Coexpression M15472 Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.72E-12 5.36E-08 1.45E-09 1.44E-08 87 366 "ADRB2,NME5,KIAA1324,SRPX,ASPA,BCHE,BMPR1B,CLDN10,LONRF2,CCPG1,CFL2,CHGB,SLIT2,CNTN1,MYRIP,PLCXD3,ARHGAP24,ARMCX2,CHRDL1,DMD,ARRDC4,DTNA,DTNB,EBF1,RCAN2,LRRC17,RAB9B,CEP85L,ARMCX1,ABCA8,ST3GAL6,FHL1,FUT9,GABRB3,GCNT2,ADAM28,GHR,LYVE1,GLUL,MAP7D2,GNAO1,GPER1,FAM107A,UBE2QL1,HLF,USP51,IL6R,KCNJ16,KIT,LAMA2,LIFR,GPR155,ZNF667-AS1,MT1M,LINC00672,NEXMIF,BEX5,ALDH1L2,SMIM11A,NTRK3,PCDH9,ENPP2,SERPINI1,PLIN1,PRKACB,ZNF844,PID1,SUSD4,BEND5,FIGN,RGS4,PRIMA1,SCN7A,SNRPN,SPART,PBLD,SST,SSTR1,ERBIN,ADGRL3,TPCN2,RGMB,SYNPO2,VLDLR,CLDND1,PCDH20,STOX2" Coexpression 18451145-TableS1 Human StemCell_Kumamoto08_2005genes GeneSigDB 1.14E-11 1.29E-07 3.40E-09 3.37E-08 232 1359 "ACHE,CLK4,CCDC85A,OSBPL1A,WDR35,C1QTNF1,CEP126,APBB2,GAS7,APLP1,DDO,ZFYVE28,ARRB1,RGS20,ARRB2,PLA2G4C,EIF4G3,ATP6V1G2,ADAM23,CFLAR,DST,WASF1,DDR1,CAPN3,CAST,ZNF501,KRIT1,SLC16A4,CBFA2T2,ZMYM4,DIS3L,SOCS6,RAB28,TPP1,PCYT1B,WHRN,COL4A5,LETMD1,ABI3BP,RTTN,NECTIN3,PREPL,VCAN,SOCS5,PDE4DIP,CNTNAP2,CST3,DZIP3,GAPVD1,ZNF337,KIF26A,DAPK1,DCTN1,DGCR5,KLHL3,DMPK,DNAH9,NR1D2,AASDH,EDIL3,EDNRA,HIPK3,FCF1,CNNM1,EGFR,KMT5B,ASB3,IRAK4,TNK2,TMEM35A,HSD17B14,VPS13B,RRAGB,SIRPB1,GMPR2,CD320,EZH1,F8,SH3YL1,SCML2,FCGRT,GTF2IRD2,OLFM1,AMOTL2,FHL1,RGPD5,COQ5,NBEA,POMT1,ATP6V1H,CGREF1,MSANTD4,AP4B1,GABBR1,GALNT15,GABRB3,GAD1,IQGAP2,SESN1,GHR,RAB40B,STMN2,PARD3B,GSTM5,HNF4G,ZNF491,EID2B,IDH3A,SOWAHA,SCIN,IL12A,INPP1,INSM1,L1CAM,MAP4,MAPT,MEST,KITLG,MITF,MMP16,BLOC1S2,LAYN,MYO5A,MYO6,MYO7A,MYO9A,NF1,NPR2,OGG1,ETFRF1,PCDHGC3,PIK3R1,PKD1,SLC25A23,PLTP,ZNF426,PILRA,FA2H,KANSL1,MAPK3,SLC26A11,MASP1,VPS13C,ANKHD1,MTMR10,TTC13,FAT4,SUSD4,RBBP6,GAL3ST4,REV3L,RNH1,ZNF532,CARF,NEK11,BAALC,TCP11L1,TNFRSF19,HSPA4L,KIF21A,HKDC1,CHD9,CNKSR2,NLGN1,ABLIM3,PPP4R3A,FAM214B,ZNF430,SLC12A4,ZNF334,SLC22A4,CPEB4,ZNF667,GKAP1,TTC17,SNCA,MBD5,SNRPN,PDZRN3,USP33,DOP1A,TRERF1,SP2,ZC3H13,LHPP,ATP10B,THSD1,SSTR1,ERBIN,ST5,TTBK2,RGL1,SULF2,ARHGEF9,SYT1,ANKRD28,SMG6,NEU4,ZFP90,TRIM2,PCDHGA10,CRTC1,CYB561A3,VWCE,ZMAT3,ZNF106,TIAM1,ICAM5,TNS1,WBP2,SYNPO2,SMUG1,RUSC1,HIRA,SGK3,UBE2H,UBTF,UGT8,MICU3,ZNF28,NDRG4,POLR3H,ZNF189,ZFAND5,GDPD5,ADAMTS9,HPS4,NAV3,PCBP4,ST7,TMEM63C,RSPRY1" Coexpression M9112 Age down-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.27E-11 1.45E-07 3.71E-09 3.67E-08 48 153 "OGT,ANK2,EP400,ATP2A2,ATP2B2,ATP6V1G2,CA4,CALB1,CALB2,CALM1,CAMK2A,CHGB,CLTB,CNTN1,NECTIN3,DYNC1I1,NR1D2,DNM1L,MBNL2,FGF12,FGF13,ATP6V1H,NSG1,GABRB3,GAD1,GFRA2,TPPP,ITPKA,MAP2,MAPT,MAT2A,MEF2C,TAGLN3,PDE4D,PRKCB,MAPK9,PTPRO,RASGRF1,RGS4,SARS,SCN2B,PPM1E,TSPYL2,SST,SYN2,CDH22,CBX5,SLC17A7" Coexpression M2105 Genes whose expression was significantly and positively correlated with the number of perineuronal oligodendrocytes in the layer III of BA9 brain region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.65E-11 1.88E-07 4.69E-09 4.65E-08 146 756 "AMPD2,BIN1,PPFIA4,APBA2,APLP1,SHROOM2,MADD,ARRB2,ADGRB2,ST3GAL5,BAIAP3,CAMK2B,CAMK2G,CCK,SYNGR3,ENTPD6,DCLK1,MYL6B,STOML1,CLTB,TMEM184B,SULT4A1,CABP1,MAGED1,COX4I1,MYRIP,CRMP1,CRY2,CRYM,IPCEF1,SLITRK5,PPP1R16B,SEC14L5,DOCK4,RASSF2,SPOCK2,IP6K1,DBN1,ELMO1,RUSC2,SNAP91,DNM1,DPYSL2,SEZ6L2,EGR3,EIF4G2,ENO2,RCAN2,NCALD,TUBB3,CORO2B,RACK1,CHST15,OLFM1,UBE2E3,DCTN2,STAMBP,RASL10A,GABBR1,CHL1,GAD1,GPR162,RUNDC3A,RNPS1,RAB40B,PRRC2B,STMN2,PADI2,ACOT7,GABARAPL2,HMGCR,MSL1,IDH3B,ITPKA,KCNF1,KCNN1,MAN2A2,PTOV1,LYRM9,FXYD7,NBL1,NEFH,NNAT,NPY,NPTX1,DPY19L2P2,PCSK1,ENPP2,SERPINI1,FXYD1,NECAB2,MAPK3,KLK6,NDUFS7,PSMA6,PTPRN,PTPRN2,IQSEC3,ZMAT4,DPF2,RNH1,RTN1,S100B,SARS,TRA2B,PUF60,FAM102A,CCDC92,SLC4A3,BTBD3,DHX30,WDR47,SMARCA4,SMARCD3,FAIM2,NMNAT2,SPTAN1,CLASP2,SST,SEPT8,STX1A,STXBP1,SYN1,SYP,COBL,TAF6,MCF2L,KIAA1107,MGRN1,PHF24,PUM2,BEX4,RIMBP2,CABIN1,WBP2,RUSC1,TUBB2A,UCHL1,CLDND1,ATP6V0E2,SPHK2,REEP1,RNF103,TUBA1A,NELFE,AP3B2" Coexpression 19658189-TableS5 Human EmbryonicStemCell_Xu09_622genes GeneSigDB 2.51E-11 2.85E-07 6.96E-09 6.90E-08 104 483 "NDRG2,ADCY5,ADCY6,RNF150,ADRB2,MTUS1,AGT,ANK2,MYH7B,PPFIA4,CPNE5,PLA2G4C,CADPS,SLC4A4,ATP2A2,SLC2A11,MYOM1,GPR146,CAMK2A,CAMK2B,CAPN3,CAST,USP2,RGN,CDH2,QKI,AKAP6,CRY2,ARHGAP24,KLHL3,DMD,DMPK,NR1D2,CPEB2,DTNA,FRY,YAF2,PHF20L1,RAB9B,ABCA8,DLC1,FECH,PRKAG2,FLNC,FOLR2,PDLIM5,PPARGC1A,GP1BB,PLPP7,BVES,ATOH8,FRMD5,FRMD3,ICA1,IDH3A,JAK2,KCNH2,KCNJ5,LAMA2,MAP4,MBNL1,ADAM11,TM6SF1,MEF2C,MITF,PDE4D,PFKFB2,PGAM2,DUSP26,PLCL1,FXYD1,SCHIP1,MASP1,PTPRE,ZCWPW1,SCN2B,MRAS,SH3BGR,CPEB3,MYO18A,SHC4,FHOD3,SLC4A3,FAM81A,LIMS2,SLC8A1,CPEB4,SMARCD3,ARHGAP26,SPTB,TPM1,TPM2,SYNPO2,OSBP2,VIPR2,ZNF540,NDRG4,REEP1,SLC30A3,PRDM8,RNF103,EPM2A,MSRB3,DPF3" Coexpression M16651 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.73E-11 3.10E-07 7.39E-09 7.32E-08 152 802 "TMCC3,ADD1,PLEKHH1,GPRASP2,APBB2,EPB41L5,NT5C3B,CDK10,CDK13,ZSCAN18,ATP1A1,SLC4A4,ZNF599,CFLAR,PROM1,KSR1,SYNJ2,ARHGEF7,MTMR3,DDR1,CACNA2D1,CAPN3,CLDN10,LRRFIP1,MAGI1,SRSF11,SLIT2,FBXO7,QKI,HECTD1,ABCG1,LRIG1,CST3,PPP6R2,BOC,GPRASP1,TCAF1,DCAF8,CENPL,YTHDC1,DMD,NR1D2,CDON,DTNA,ECM2,WDPCP,TSPAN5,EDNRB,HIPK3,FCF1,TMTC1,FAM13A,KMT5B,RASA4,ERBB2,MRVI1,ABCA8,SH3YL1,FDFT1,TMEM164,PRKAG2,PCYOX1,ZBED3,PDLIM5,ERAP1,GATM,SESN1,GLUL,ZNF638,RAB40B,GNAL,LNX1,GSN,AP4S1,MGC16275,ST7-AS1,LIFR,SMAD9,MARK3,MATN2,MBNL1,MBP,MIA2,AFDN,MXI1,LYRM9,MYO9A,NF1,PDCD2,PRTG,ENPP2,PFKFB2,PIK3C2A,ZFYVE21,EPB41L4B,KANSL1,VPS13C,SNRK,MTMR10,PTPN13,PTPRB,PTPRG,PID1,ZNF493,HKR1,MSANTD2,RPL15,FAM161B,CLIP1,ZNF331,CASC3,GALNT10,SUPT20H,SGK1,ASAP3,CHD9,CCDC92,ATF7IP,CPEB4,LIMCH1,KDM4B,FNBP1,SPP1,TEX2,POGZ,ITPRID2,ERBIN,ST5,KANK1,SYNE2,TMEM150C,ANKRD28,TCF4,NSD1,SIK3,DICER1,BEX4,TNS1,C9orf85,PPIL6,SSBP2,HIRA,UBTF,TOM1L2,TMEM178A,EPM2A,FZD3,RNF170,TTC7A,KLHDC1,RNF146,SPATA13" Coexpression M2808 Genes up-regulated in neurons. MSigDB C6: Oncogenic Signatures (v6.0) 5.83E-11 6.62E-07 1.54E-08 1.53E-07 36 100 "SYT13,CPNE5,CALB1,CAMK2B,CCK,CRHBP,GDA,KIAA0319,SV2B,HS3ST2,DYNC1I1,ENO2,RASL10A,GABRG2,SLC6A17,ITPKA,MEF2C,MYH3,NEFM,TRHDE,RGS4,SLC8A1,NAPB,CLSTN2,SST,STX1A,STXBP1,SYT1,SYT5,SATB2,PHF24,ICAM5,CELF4,LAMP5,PRDM8,CPNE4" Coexpression M1954 Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.12E-11 8.08E-07 1.84E-08 1.82E-07 95 434 "ASIC1,ACHE,EMILIN3,ELFN2,ADORA2A,DPP10,SEMA7A,CPNE5,ATP2B2,ADGRB1,ADGRB2,JAZF1,CACNA1I,CACNA1G,CABP7,CAMK2B,CBLN1,CCK,DLGAP2,CLGN,NOG,CRLF1,CACNA2D2,SLIT2,MYRIP,C1QL2,RIMS4,PDE4DIP,RASGEF1C,DBN1,ZNF804A,HS3ST2,CNNM1,TMEM132E,EPHB1,RASL12,CORO2B,FGF12,PSD2,DLL3,HHIPL1,CYP46A1,AIFM3,CCDC184,GRB10,GRIA2,C1QL4,GRIN2C,PTPRT,IRF8,NKD1,SLC6A17,ITPKA,KCNH2,KCNQ3,L1CAM,NEFH,NELL2,NPTX2,NTRK3,OXTR,PDE1B,TRHDE,SDK2,NECAB2,IRX1,VSTM2L,SKOR1,RELN,PTPRB,FAM184A,LGI2,SCN8A,STUM,ARX,ABLIM3,LGI3,MYO16,MYCBP2,CLSTN2,SSTR1,PDLIM2,WSCD1,PHF24,PCDHAC2,CDH22,DOK6,NEIL2,FAM155A,RBFOX3,ZIC1,CELF4,LAMP5,TMEM178A,JPH3" Coexpression M5547 Age up-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.29E-10 1.46E-06 3.24E-08 3.21E-07 66 262 "AGT,BBOX1,RGS20,SLC4A4,BMP7,IL33,DDR1,CAST,CBS,RGN,QKI,IQCK,COL4A5,ABCG1,LRIG1,VCAN,PDE4DIP,GREB1,TCAF1,RASSF2,HEPH,MFAP3L,ECM2,PLXNC1,EYA1,FGF1,FGFR3,AMOTL2,PDLIM5,FYN,GATM,FERMT2,ADGRA3,GSN,CLASRP,HP,IFI16,ITPKB,LAMP2,AFF1,NFE2L2,NTRK2,OGG1,PIK3C2A,FXYD1,PLXNB1,PMP22,SEPT4,ELOVL2,PTPN13,RDX,RNASE1,S100B,SCP2,SLC14A1,ZNF423,ITPRID2,NXT2,KANK1,SYPL1,FAM208A,FRYL,TP53BP2,TST,SEMA3B,EPM2A" Coexpression M9178 Genes down-regulated in CD4 [GeneID=920] T conv over-expressing: GATA1 and SATB1 [GeneID=6304;2623] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.31E-10 1.49E-06 3.24E-08 3.21E-07 55 200 "ACADM,ACTN1,ADCY6,RNF157,ARHGAP20,MAP4K3,PKP4,BCAS1,SFMBT2,RASL11B,NRP2,C5,CA8,DDR1,ZMYM4,ABCG2,MAP4K4,CRY2,DZIP3,GREB1,GPSM1,ARHGAP24,KIAA0586,DAPK1,ANKRD46,EIF4G2,ENO2,EPB41L2,ARMCX1,ADAMTS6,ZDHHC15,CELF5,MSL1,KCNH2,KIT,KTN1,HECTD2,SRSF12,KCTD6,SMOX,MAPK7,GTDC1,SATB1,ATXN2,RASA3,DZIP1,ST8SIA1,POGZ,LARP4,AGTPBP1,KLHL4,TP53BP1,TTC3,TUBB2A,NT5M" Coexpression 19286929-SuppTable2a Mouse Lung_Rangasamy09_168genes GeneSigDB 2.15E-10 2.44E-06 5.18E-08 5.14E-07 46 154 "PCDH10,APC,DOCK11,ADAM23,NRP2,CCNH,CDC25B,CDH2,SLIT2,NRXN3,ARMC8,NECTIN3,CNTNAP2,CDON,DOCK2,EDIL3,PCDH17,GP1BB,NEGR1,ITGAM,LSAMP,NCAM2,NRCAM,PCDH9,PCDH18,SEPT4,PCDHB17P,PPP3CA,FAT4,RBBP8,KIF16B,NLGN1,RADIL,CDK19,RBM26,CLASP2,SEPT8,SEPT3,PLCB1,PCDHGA11,PCDHB9,TEK,RGMB,PCDH20,SMARCAD1,CADM2" Coexpression M2013 Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.96E-10 3.36E-06 7.00E-08 6.94E-07 95 445 "SYN3,NCKAP5,ADCY6,ZNF608,CC2D2A,SPARCL1,ABCD2,ANK2,ATP6V1G2,TTLL9,BCHE,SYNJ2,TPP1,STOML1,AKAP7,PCYT1B,COL4A5,SUMF2,SMARCAL1,RTTN,KIAA0408,HDAC9,KATNAL2,TCAF1,DGKB,ALKBH8,CD99L2,SLC12A6,DTNA,FIS1,KLHL5,FAM13A,MBNL2,TMEM35A,ETV1,ABCA8,ATP13A4,SYT3,TRIM16,BRSK1,MEGF10,GABRG1,GHDC,PPARGC1A,ZNF276,LOXL3,LPAR4,GPER1,PLPP7,GRIK5,ADAMTS6,CPT1C,HSPA1L,KCND2,LINC00672,NDP,IDNK,P2RX7,PCDH9,PDE1C,PDE4B,GNG2,SERPINI1,LRRN3,MAPK10,WBP1L,PTN,ZIK1,PPP2R3C,SUSD4,ARMH4,FBXW7,ADAL,TRAPPC13,S100B,DGLUCY,CSRNP3,MTERF2,CPEB4,INTS9,TSNAXIP1,ZC4H2,ST5,ADHFE1,ARHGEF9,SYT1,TPCN2,ACTR6,SMUG1,ZKSCAN5,TSPAN11,FTSJ1,DNALI1,MDH1B,NAV3" Coexpression M17937 Top 100 probe sets contrubuting to the negative side of the 1st principal component; predominantly associated with synovial sarcoma and myxoid/round cell liposarcoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.08E-10 4.63E-06 9.45E-08 9.37E-07 29 74 "SEMA6A,APBA2,CACNA1G,HIP1R,CRLF1,LHX2,COL4A5,COL9A3,SEZ6L2,EDN3,EMX2,OLFM1,FGFR3,TOX3,ADGRA3,GPD1,NEFH,NNAT,NPTX2,NTRK2,EPB41L4B,PPP1R1A,RET,SOX11,PEG10,CUX2,RIMBP2,TRO,ITM2C" Coexpression M16478 Genes down-regulated in medulloblastoma tumors from animals with inactivating mutations of one copy of PTCH1 or SUFU [GeneID=5727;51684] in conjunction with TP53 [GeneID=7157] loss. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.26E-10 4.84E-06 9.68E-08 9.59E-07 31 83 "ATP2A2,ATP2B2,KIF1A,CACNA1G,CA8,CALB1,CBLN1,DCLK1,NRXN3,PREPL,SPOCK2,SEZ6L2,RCAN2,GAD1,CSDC2,GUCY1A1,ITPKA,KCND2,KIF5A,MAP4,NEFH,SKOR1,MASP1,MEG3,SLC8A1,NAPB,FNBP1,CLSTN2,SYT1,VSNL1,NDRG4" Coexpression M14127 Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.38E-10 4.98E-06 9.76E-08 9.68E-07 97 461 "C3orf14,ALCAM,BIN1,APLP1,CDC14B,CACNA1G,WASF1,BAIAP3,CALM1,SPAG9,CCK,SLC16A4,LHX2,SLC4A8,AKAP12,CNTNAP2,DZIP3,CTH,DBN1,ARMCX2,AASS,TENM1,RASGRP2,CDKL3,TUBB3,TAOK3,FER,FGFR1,FGFR3,BAIAP2,FHL1,PDLIM5,CGREF1,CSPG5,TOX3,GLUL,PCLO,GSN,RNFT2,HBA1,ACOT7,ITGA7,KCNN2,KHK,L1CAM,LIFR,MAPT,MEF2C,MYCN,NFYA,NPTX2,PCDH9,CDK18,ENPP2,PFKFB3,ABCB1,SERPINI1,GPSM2,PLEC,SEPT4,PRKCB,PRPH,PTK2,RADX,NUDT11,RPS6KA2,RPS20,SCP2,SMPD3,SH3BGR,SH3GL3,PPM1E,DZIP1,ANKRD6,SLC6A8,OGDHL,SMARCD3,SNAP25,DOP1A,ZSWIM8,IZUMO4,SPP1,PEG10,ZBTB43,SYN1,SYT1,CAMTA1,ZMAT3,BEX4,TPM1,RUNDC3B,TST,SGK3,PLPPR2,CLIP2,TUBA1A,SLC17A7" Coexpression 18787218-tableS1 Human Liver_Chao09_1031genes GeneSigDB 6.38E-10 7.25E-06 1.40E-07 1.38E-06 130 684 "ELFN2,TMCC3,ADORA2A,ESYT2,OSBPL1A,BIN1,VAT1L,RGS20,ZBTB10,RNF182,NRP2,BMP7,DST,SYNJ2,SGCE,ARHGEF2,CDH2,NOG,UBE2L6,CHGB,CNN3,MAGED1,AHCTF1,AKAP12,DOCK4,DGKG,MFAP3L,GSDME,NR1D2,DPYSL2,FIS1,E2F5,SNX29,TSPAN5,EDN1,PLXNC1,PCOLCE2,ETV1,CORO2B,DLC1,ST3GAL6,CHST15,FGF1,PRKAG2,FHL1,FOXF2,KHDRBS3,SYT17,GRB10,GUCY1B1,RASSF8,FRMD3,IFI16,FAM69A,L1CAM,TTYH2,LSS,SMAD9,MARK1,MATK,MBP,MKLN1,AFDN,MN1,MYO6,BEX5,NBL1,NOVA1,NPTX2,NRCAM,PRTG,SLC10A4,SLC25A23,MAPKAP1,SH3KBP1,DRAM2,PPARA,PPP3CA,CNNM2,ZIK1,PTPRG,TUG1,PID1,OXR1,RASGRF2,FIGN,STK32B,SALL1,TNFRSF19,PEAR1,SEC14L1,SGK1,FERMT1,KIF16B,HKDC1,FHOD3,ABLIM3,DHX30,SLC14A1,ZKSCAN3,DOK5,SPP1,PEG10,ZC4H2,SS18,DIP2A,KANK1,SULF2,PDLIM2,FBXW11,PCDHB6,PCDHAC2,SLC35G2,FAM200B,TIAM1,NACC2,HEY1,CBX5,BEX4,PARD3,TRPM2,TTTY15,UBE2H,UGT8,VLDLR,ZNF711,LYPD6,PRTFDC1,UBE3B,NHSL1" Coexpression M18979 "Genes up-regulated in T1 cells (primary melanoma, sensitive to TRAIL [GeneID=8743]) compared to G1 cells (metastatic melanoma, resistant to TRAIL)." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.43E-10 8.44E-06 1.59E-07 1.58E-06 115 584 "ACADM,OSBPL1A,OSBPL8,CDC42BPA,APC,BLM,BMP7,CAST,CCK,KRIT1,CCNH,SRSF11,COL9A3,DZIP3,APPL1,TCAF1,ZFYVE16,JAKMIP2,MYEF2,KIAA0319,DDX46,SACS,DYNC1I1,CASP8AP2,DNM1L,OPTN,PHF20L1,PLXNC1,NSRP1,RPS6KC1,TAOK3,FER,OLFM1,FGF13,POLK,SUCO,SMC2,FYB1,ZNF44,RAPGEF6,IQGAP2,PPARGC1A,DBF4,ZNF638,HTATSF1,HAS2,ZHX1,IFI16,IGF1,KIT,IPO5,KTN1,LIG4,MATN2,MID1,MITF,MYO5A,MYO6,MYO9A,NUCB2,OPA1,PCSK5,ENPP2,SNX10,RETREG1,VPS13C,SPDL1,PTPN13,USP47,RAD17,RBBP6,RBBP8,RDX,REV3L,PBRM1,CLIP1,TRAPPC13,AP1AR,RMI1,SCP2,HSPA4L,DZIP1,ZNF430,BTBD7,ATF7IP,ARFGAP1,GKAP1,SNAP25,BDP1,MYCBP2,SPP1,RBM26,ZNF302,SULF2,FAM208A,AGTPBP1,TCEA1,TCF4,TRIM2,DOCK9,SLC35G2,ITGB3BP,UBE3A,USP1,VLDLR,WRN,NPDC1,XPO1,XRCC4,ZBTB38,ZNF195,SMARCAD1,UPF3A,ACTR3B,FXR1" Coexpression M15107 "Genes up-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.16E-10 9.27E-06 1.70E-07 1.68E-06 73 315 "KIAA1211,LRCH2,DPY19L3,PROM1,DST,WASF1,SOCS6,B4GALT6,ARHGAP22,ZNF521,FAM171B,CRHBP,TCAF1,DAPK1,SCRN1,ARMCX2,RHOBTB1,SPOCK3,CHRDL1,KCTD3,ARMCX1,PRMT5,FHL1,ZBED3,ATP2C1,KHDRBS3,ZMAT1,IQGAP2,GATM,ADAM28,HPGDS,ADGRA3,GUCY1A1,MUM1,HLF,HMGCR,NEGR1,KIT,STMN1,SMAD1,MEIS1,MEST,CYTL1,FAM98B,KCTD15,FAM216A,SCHIP1,TUG1,RDX,BAALC,MEG3,ANKRD6,PREX2,BTBD3,LIMCH1,PDZD2,SPART,POGZ,ZNF302,NKAIN2,PLCB1,SYPL1,ANKRD28,OBSL1,CBX5,TRO,SSBP2,ZNF709,ZNF711,MICU3,ITM2C,MSRB3,FRMD6" Coexpression M7562 Genes up-regulated in CD11b+ cells from BALB/c mice: spleen versus bone marrow. MSigDB C7: Immunologic Signatures (v6.0) 8.20E-10 9.32E-06 1.70E-07 1.68E-06 53 198 "RNF157,GPRASP2,LRCH2,ATP1A3,ST3GAL5,MTMR3,DDR1,TIGD7,MAP4K4,ARMC8,ENTPD4,NCOR2,KIAA0753,RCAN1,FAM78B,PHC2,ENO2,EXTL2,ARMCX1,PTK2B,AMOTL2,ATP6V1H,BRSK1,ABLIM2,CSDC2,CCDC184,STMN2,RNF165,SMAP1,EID2B,IFI16,CHIC1,PTOV1,PALM,GPR85,SLC26A11,PTCH1,TTC13,RASGRF1,ZNF354C,CNKSR2,SIRT2,MAST1,USP33,PDZD2,CDK19,STXBP1,CLASP1,SYNE1,FAM155A,ZNF70,REEP1,ZNF177" Coexpression M7617 Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [GeneID=8726] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.30E-10 1.06E-05 1.87E-07 1.86E-06 183 1062 "ADCY8,LRFN2,SLC24A4,KIAA1324,SORCS2,ARHGAP20,PCDH10,LRCH2,LCORL,LGR5,ZFYVE28,ARNTL,RGS20,CHRD,ATP1B3,DOCK11,BMPR1B,CACNA1G,CACNA1B,HAP1,CAMK2B,CH25H,CBLN1,DGKI,DCLK1,NOG,CRLF1,CHN2,B4GALT6,SLIT2,LHX2,VAX2,CNTFR,COL4A5,NRG2,CNRIP1,CRHBP,GDA,RGS6,CSNK1E,PDE4DIP,CENPL,DGKG,SCRN1,LYPD1,GSDME,SNAP91,SV2B,SPOCK3,DLX1,GRIN3A,EBF1,CNNM1,RASGRP1,EEF1D,YAF2,EGFR,EGR3,PLXNC1,TMEM132E,EMX2,EPHB1,ERBB4,NRN1,ABCA8,BAIAP2,HPCAL4,FOXF2,ZMYND15,PSD2,AFF2,TRMO,RASL10A,TPPP3,MEGF11,GAD1,B4GALNT1,PCDH17,GHR,NTNG2,MAP7D2,DCLK2,GPR12,STMN2,GRIA2,PTPRT,BVES,SOX21,GUCY1A1,ATOH8,IRAK3,HBA1,FRMD3,BACH2,HLF,HSPA1L,SHISA6,SCIN,LRRTM1,ITPKA,KCNQ3,CREG2,MAPT,TM6SF1,MID1,MT1M,HS6ST3,LAYN,HNRNPM,NEFM,NFIX,NPTX1,NPTX2,NRCAM,NTRK2,PAX6,DPY19L2P2,PCDH8,SLC10A4,TMOD2,PLEC,PMP22,TRHDE,EPB41L4B,PRKCB,MAPK4,DCHS2,RELN,CNNM2,ELOVL2,EML5,SUSD4,RASGRF1,CRTAC1,STK32B,RYR3,SEMA6D,LRFN5,GALNT10,PPM1E,FUZ,SHC4,ST8SIA1,FAM81A,PKNOX2,TRIM67,DMRTC1,PDZD2,SOX3,CLSTN2,MESP1,SSTR1,SSTR2,NKAIN2,PLCB1,ASTN2,TAL1,ADGRL3,CHST8,HEY1,ICAM5,NR2E1,CSMD1,PARD3,DOK6,ANKRD20A2,FLRT2,VGF,VIPR2,WNT7A,KCNK12,ZIC1,ZIC2,ZNF711,TRIM9,LAMP5,UPF3A,SLC30A3,SLC30A4,KCNAB1,JMJD1C,DPF3,ST8SIA2" Coexpression 19377508-SuppTable1 Human Lymphoma_Chin09_1201genes GeneSigDB 9.51E-10 1.08E-05 1.87E-07 1.86E-06 131 695 "TMEM132B,CCDC85A,RNF150,PTCHD1,SLC24A4,AP2A2,HECW2,WDR35,SPARCL1,SYT13,PITPNM2,AMPD3,LRCH2,EP400,FGD2,BCAS1,ARNTL,PLA2G4C,ZBTB10,SLC4A4,AZGP1,MPDZ,RGS9,CFLAR,SGCE,CBS,SLC16A4,CD38,LHX2,CNR1,WHRN,AKAP5,ABI3BP,MYRIP,PDE4DIP,PPP1R16B,ARHGEF4,RIMS2,GPSM1,MYADM,SPOCK2,KLHL3,TMCC2,DMD,HIPK3,EBI3,PLXNC1,PCOLCE2,CALCRL,ERBB2,PIPOX,ABCA8,TBC1D16,TUBB3,FGFR1,KHDRBS3,FYB1,CHL1,ADAM28,PPARGC1A,GPD1,GPD2,GRIN2C,GRM8,PTPRT,FAM19A2,ADAMTS6,GUCY1A1,GUCY1B1,HBA1,BACH2,SYNPO,IGFBPL1,IL6ST,ITPKA,KCNN2,LSAMP,SMAD1,GPR155,MAP6,AQP11,MEIS1,MSR1,MYO7A,NCAM2,NELL2,NTRK3,NUCB2,IGSF11,P2RX7,PCDH9,PDE4D,SMOX,PURG,SCHIP1,EPB41L4B,PKIA,MAPK10,PRPH,SNRK,PTPRG,PTPRN2,ZDHHC14,RDX,ROBO1,ROBO2,ADAL,RPS6KA2,RTN1,RXRA,SMPD3,MRAS,HSPA4L,NLGN1,BTBD3,SLC22A4,PLCB1,TPCN2,CDH22,HEY1,TLR4,TPM2,NEIL2,PPIL6,SSBP2,TRIM9,FSTL5,MDH1B,NAV3,KLHDC1,DPF3" Coexpression M10761 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.56E-10 1.09E-05 1.87E-07 1.86E-06 79 353 "ABHD6,APAF1,EPB41L5,TNRC6C,ARRB1,MARCH3,KSR1,SYNJ2,CABP7,CAPN3,NPIPA1,FOXN3,SLIT2,QKI,ARHGEF6,WHRN,COL9A3,ZNF385A,PDE4DIP,PPP1R16B,RCAN1,SEZ6L2,RASGRP1,FRY,RASGRP2,APC2,DLC1,FGF13,FOXF2,SEMA4D,FOLR2,KHDRBS3,OGA,GPT2,GP1BB,GPR37,LINGO1,UBE2QL1,HSPA1L,SHISAL1,KCNH2,KCNK3,KIT,LMO2,SMAD9,HS6ST3,MX1,LINC00672,NPTX1,OXTR,PCSK5,PLCD1,EPB41L4B,PPP2R2C,PPP3CC,PSD,PTX3,RET,HUNK,SEMA6D,ARX,SHC4,NBPF1,LIMS2,GKAP1,TMCC1,UNC5B,ARHGAP26,SYNE2,TACC1,FRYL,HEY1,ZIC2,ELFN1,REEP1,STOX2,ADAMTS10,ST8SIA2,SPATA13" Coexpression M1884 Genes up-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-09 1.17E-05 1.97E-07 1.95E-06 216 1305 "RALGAPA1,KCNH8,ACHE,UNC5A,ADRA1D,ADRB2,AGT,AK2,ALCAM,BEGAIN,BIN1,APBA2,KCNAB2,APC,GAS7,AQP6,MADD,ARRB2,ASGR1,ATP1A1,ATP1A3,ATP2B2,AZGP1,RGS9,BMP7,NAE1,GPC2,CACNA1A,DDR1,CACNB4,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CAPN3,RHBDL1,ISPD,CBS,CCK,MTMR7,ENTPD2,CDC25B,KCNAB3,DLGAP2,CDO1,DLGAP1,CHGB,CHN1,CHRNA4,LHX2,PPT2,RAB26,CNGA3,CNTN1,COL9A1,COX4I1,CRHBP,SH2B1,AKAP12,CRYBB1,DBN1,SNAP91,SV2B,GRIN3A,DPP6,DNM1L,WDPCP,EDN3,EDNRA,HIPK3,APH1A,EGFR,EGR3,PLEKHA1,CALCRL,COQ7,ENPP6,ERBB2,ERBB4,EXTL2,ACSL4,DLC1,OLFM1,POLR1B,FGF14,HPCAL4,EVL,SYT3,CAMKK2,ST6GALNAC3,CSPG5,NSG1,DLL3,GABBR1,HRASLS5,GABRA3,GABRB3,GABRG1,GABRG2,CPLX2,LYVE1,GNAL,ADAP1,PLCD4,GRIK4,GRIN2D,GRM8,GSTT2,PADI2,FRMD5,ACOT7,SYNPO,HP,MYLK2,IGF1,ITPKA,ITPKB,JAK2,KCNB1,KCND2,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNN3,KCNQ3,KHK,KIT,L1CAM,CAMK2N2,LSAMP,MAP2,MAP6,MAPT,MAT2A,SHC3,KITLG,AFDN,PTOV1,MXI1,NEFH,NELL2,NF1,NPY,NPTX2,NRCAM,NTRK2,NTRK3,OXTR,PDCD2,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PFKFB2,PFKFB3,PGAM2,NLGN3,NALCN,FXYD1,MTRF1L,TRHDE,EPB41L4B,SH3KBP1,PPARA,MINDY2,PPP1R1A,PRKCB,MAPK3,PRPSAP2,MASP1,PSMA6,PTK2,PTPRE,PTPRH,PTPRN,RET,RTN1,S100B,MAPK12,SCN7A,MRAS,KIF27,CNKSR2,NLGN1,ST8SIA1,WDR37,SLC4A3,SLC6A11,ARFGAP1,SNAP25,SNCA,DDN,SST,SSTR1,SSTR2,STX1A,ARC,SYN2,TACR1,MCF2L,EXOC7,PCDHGA11,CDH22,CBX5,TLR4,CABIN1,TST,UBE3A,UCHL1,VSNL1,NDRG4,DOCK8" Coexpression 19605494-TableS1 Mouse Skin_Driskell09_1322genes GeneSigDB 1.04E-09 1.18E-05 1.97E-07 1.95E-06 144 786 "ACTN1,GALNT16,TMCC3,RNF150,KLHL13,OSBPL6,SORCS2,PCDH10,GPRASP2,APOC1,LGR5,CDC14B,ARNTL,PDE8B,ZSCAN18,SLC4A4,BMP7,BTK,CACNA1B,CACNA2D1,CBLN1,CDH2,B4GALT6,NDST3,LHX2,FAM19A5,CNTFR,CLOCK,GDA,CSF1,RGS6,LRIG1,PHACTR3,PLXNA4,PITPNM3,ERC2,CYBB,GPRASP1,ARHGAP24,LONRF1,CHRDL1,NR1D2,DOCK2,EBF1,EDN3,EDNRB,CNNM1,TMTC1,EGFR,PLXNC1,RASA4,CERCAM,ELN,EPHB1,NCALD,PIPOX,NRN1,MED12L,FGFR1,FLT1,PSD2,FAM49B,ST6GALNAC3,FYB1,GCNT2,GFRA2,FREM1,PCDH17,CSDC2,HPGDS,MCHR1,STMN2,CIT,SOX21,GUCY1A1,TOX2,FRMD3,NCKAP1L,HLF,HSF2,JAK2,METTL21A,KIF5A,KIT,LAMA2,CAMK2N2,ASPRV1,MSI1,NBL1,NDP,VWA2,NOVA1,NPTX2,NTRK2,NTRK3,OXTR,CNTN3,PDE3A,PDE1B,ENPP2,SLC25A23,PILRA,PPP2R2C,PRKAR1B,PRKCB,PID1,TMEM255A,FAM184A,GAL3ST4,RET,RGS4,SLA,PREX2,KIF13A,SNRPN,SOX11,CDK19,CLSTN2,SAMSN1,THSD1,SS18,STAC2,ARHGEF9,SYN2,COBL,ANKRD28,ASTN2,DMXL2,PCDHB9,PCDHB3,TNS2,ARHGAP9,HEY1,RPRM,FLRT2,ZIC1,CADM2,DNALI1,PLSCR4,RGS7BP,FZD3,DOCK8,NETO2,CPNE4" Coexpression 19605494-TableS3 Mouse Skin_Driskell09_685genes GeneSigDB 1.20E-09 1.36E-05 2.23E-07 2.21E-06 92 437 "ACTN1,INTS2,SEMA6A,SEMA7A,PPP4R4,TMEFF1,PTCH2,DPY19L3,KSR1,DST,CACNA1G,CD38,ABCG2,HAPLN1,ANKRD44,GDA,CRYM,GALNT9,PLXNA4,PPP1R16B,GPSM1,DOCK4,HDAC9,RIPOR2,SACS,DLX1,DMD,HEYL,TMTC1,FRY,CALCRL,DENND4A,MRVI1,PTK2B,ST3GAL6,FLT1,GABBR1,GALNT15,GCNT2,LYVE1,BRD8,MCHR1,L1CAM,TTYH2,LMO2,LSAMP,SRSF12,TAGLN3,HNRNPM,PIK3R1,PCDHB17P,PPP3CC,SKOR1,GDPD1,PTPRB,PTPRG,RASGRF2,TRIM68,SLC25A36,LRFN5,MRAS,ABLIM3,SLC14A1,SLC22A4,TET1,CXXC4,MBD5,KIF13A,SNRPN,SOX11,UNC5B,CDK19,LMO3,SYNE2,PLCB1,SYP,ANKRD12,SYNE1,DOCK9,ARHGAP9,FRYL,TEK,TIAM1,UCHL1,REEP1,DPYSL5,ANKS1B,SLC38A1,SEMA3B,FAM13C,FZD3,DOCK8" Coexpression 15361855-SuppTable1 Human Ovarian_Donninger04_1191genes GeneSigDB 1.84E-09 2.09E-05 3.33E-07 3.30E-06 169 970 "ABR,AXIN2,BRAP,AP2A2,MTUS1,C1QTNF1,C1QTNF3,AMPD2,BIN1,OGT,MAP4K3,PARG,APAF1,APOC1,CDK10,ARHGDIA,ZBTB10,BARD1,BBS2,BMP7,DST,MTMR2,AP1M1,CACNA1A,CALB2,PTBP2,CAST,CLDN10,LONRF2,LRRFIP1,L3MBTL4,SLIT2,TPP1,ARMC8,AHCTF1,CREM,RBM39,LRIG1,LRRC3B,ARHGEF10,PDE4DIP,BOC,DOCK4,HDAC9,HDAC4,IP6K1,GIT2,DBN1,GSDME,DMD,CDON,DPYSL2,ARRDC4,DTNA,MAMLD1,EBF1,EDN1,SEMA3D,PCOLCE2,ERBB4,SPEG,ARMCX1,ABCA8,CEP78,CHST15,FECH,AMOTL2,FHL1,FLNC,NBEA,CELF1,STAU2,SARAF,GABBR1,FAM120B,GALC,RAPGEF6,ZNF274,GHR,GLUL,GPD2,GSTM5,GUCY1B1,RASSF8,ZHX1,PACSIN2,FRMD3,KCNB1,SMAD1,LYPLAL1,MBP,MEIS1,MEIS2,POC1B,ZNF92,CLDN11,GPR137C,PALM,PDE3A,PIK3C2A,PMP22,ING3,RETREG2,EPB41L4B,PILRA,DEF8,PTK2,PTN,PTPRG,TUG1,RNASEL,RNH1,SETD5,ELP2,SEMA6D,PUF60,PREX2,BTBD3,ZNF430,SEPHS1,EPC1,SMARCD3,TTC17,SNCA,LMBRD1,TMCC1,KDM3A,ZC3H13,TSPYL2,SPART,NFASC,ZNF302,NXT2,NEK4,VPS13A,ADAMTS17,ANKRD28,TACC1,CAMTA1,KIAA1107,IQCE,TPCN2,PCDHGC5,DOCK9,PCDHB10,OBSL1,PCDHAC2,PUM2,TNS2,CYB561A3,ZFPM2,TMPO,TPM2,TRO,TRPS1,FLRT2,USP1,CRB2,ZNF138,REEP1,SPIRE1,MAP3K12,STOX2,MDH1B,PLSCR4,FZD3,JMJD1C,TTC7A,FXR1" Coexpression M12921 Genes up-regulated in brain from patients with Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-09 2.10E-05 3.33E-07 3.30E-06 266 1690 "BRAP,MTUS1,AK2,SPOP,SRPX,AMPD3,BIN1,EP400,APOC1,LGR5,AQP6,CDK10,SEMA4G,CASK,CDK13,ZBTB10,NUMB,SLC4A4,MYOM1,AZGP1,RGS9,NRP2,CFLAR,DST,GYG2,CACNA1G,C5,MYRF,LDLRAD4,CFAP410,CACNA1A,DDR1,CAPN3,CAST,CH25H,HIP1R,SPAG9,RGN,CD86,SCARB1,CDC25B,ZMYM4,LRRFIP1,LARGE1,CRLF1,FOXN3,TAOK2,FAM189A2,QKI,HOMER3,PICK1,ARMC8,WHRN,COL4A5,GAL3ST1,AHCTF1,CRHBP,NCOR2,AATK,CSF1,SEC24C,ARHGEF10,CSNK1E,VCAN,PUM1,RIMS2,HDAC4,ZNF337,TBC1D5,DGKG,DAPK3,PITPNC1,HEPH,FBXL5,DMD,DMPK,USP3,DTNA,ECM2,TOM1,DUSP9,E2F5,TSPAN5,EDNRA,PHC2,EEF1D,EGFR,EIF5,IRAK4,ING4,C3orf18,USPL1,TUBD1,COQ7,RASGRP2,ERBB4,IGSF6,RASL12,FDFT1,FGF1,POLR1B,FGFR1,FGFR3,AMOTL2,FOXO3,FLNC,NOP56,FYN,ZNF274,IQGAP2,ERAP1,SEPT9,INPP5K,NEU3,TUBA8,SRCAP,GDF9,GPR162,USP19,PCDH17,MALT1,DBF4,GLI2,STARD3,KCNMB4,ADGRA3,LILRA2,ADAP1,LPAR4,GRB10,CACFD1,CLASRP,GSTM5,GSTT2,FICD,FAM107A,PACSIN2,MAN1B1,BACH2,HMGCL,IFI16,RBPJ,TJAP1,IL6R,IL6ST,INPP1,ITGA7,ITPKB,KCNN3,KTN1,LAMA2,LIFR,LSS,SMAD1,MAN2A2,MAP4,MARK3,MAT2A,MATN2,MBP,KITLG,MID1,MITF,AFF1,MMP16,MXI1,MYCN,MYO6,HNRNPM,NEK1,NME4,NTRK3,OGG1,PAX6,PCDH9,PCSK5,PDE3A,PDE4D,PFKFB3,PKD1,PLCL1,PLEC,SMOX,ING3,PILRA,FA2H,PPM1B,PPP1R1A,MASP1,APTX,SNRK,PTCH1,PTH1R,PTPRH,RBBP6,TRIM68,RGS12,PBRM1,ZFHX4,EMID1,SAFB,MAPK12,CASC3,GALNT10,MRAS,SUPT20H,SGK1,SH3BP2,SH3GL3,ASAP3,SHMT2,FBXO11,ST8SIA1,SLC6A8,SEPHS1,SIRT2,SLC11A1,SLC14A1,ARFGAP1,SMARCC2,USP33,FNBP1,KDM3A,ZHX3,ARHGAP26,NFASC,TROVE2,POGZ,ITPRID2,LARP4,ERBIN,ST5,STAU1,DIP2A,JMJD6,ZC3H4,TACC1,FAM208A,PDLIM2,TBL1X,USP22,DICER1,THRA,R3HDM1,PARD3,KAT6B,PDSS1,TRPS1,USP1,CLIP2,LAT2,WRN,ZIC1,ZNF24,ZNF32,ZNF195,UPF3A,SLC38A1,TUBA1A,ADAMTS9,SEMA3B,PDSS2,UBE3B,KAT6A,FXR1,DPF3" Coexpression M19529 Genes down-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.96E-09 2.22E-05 3.47E-07 3.44E-06 106 533 "AXIN2,PLEKHH1,MTUS1,GPRASP2,NT5C3B,ZSCAN18,SLC4A4,DPY19L3,AZGP1,ST3GAL5,CALM1,SLC16A4,DGKI,ZBED1,MAGI1,SLIT2,FBXO7,IQCK,ABI3BP,AKAP12,LRIG1,GPRASP1,ARHGAP24,DCAF8,GIT2,PITPNC1,ARMCX2,CDON,ECM2,EDNRB,ANKRD46,FRY,FAM13A,PHF20L1,EGR3,FECH,FGF13,TMEM164,FHL1,SCARA3,ZBED3,PDLIM5,ST6GALNAC3,ZMAT1,SESN1,GHR,ZNF638,LNX1,WDFY3-AS2,ADGRA3,GSN,AP4S1,ATOH8,ZNF678,LIFR,SMAD1,SMAD9,MATN2,MEF2C,NF1,CLDN11,PDE4A,PFKFB2,ZFYVE21,SLC25A23,PCDH18,EPB41L4B,TATDN3,PKIA,SNRK,PTPRB,PTPRD,PTPRG,SNX22,ADAL,RXRA,DGLUCY,CSRNP3,SGK1,CCDC92,ANKRD6,ARHGEF40,ATF7IP,FNBP1,DOK5,TEX2,SYNE2,TMEM150C,TCF4,NSD1,SLC44A1,HEY1,BEX4,TNS1,SYNPO2,SSBP2,HIRA,TOM1L2,ZNF711,ATP6V0E2,TMEM178A,KCNAB1,PLSCR4,PDSS2,RNF170,KLHDC1" Coexpression 15374961-TableS2 Human Brain_Freije04_595genes GeneSigDB 2.05E-09 2.32E-05 3.58E-07 3.55E-06 97 474 "ACTN1,NDRG2,CCDC85A,ADCY8,GALNT13,UNC5A,CARNS1,SYT13,PDE8B,SLC4A4,ATP2B2,CA12,PRC1,CBR1,CBS,DLGAP1,SLIT2,LHX2,NGEF,COL9A3,AKAP12,VCAN,PDE4DIP,HDAC4,TMEM130,SV2B,HS3ST2,RCAN1,DTNA,EDNRB,FRY,CALCRL,RCAN2,APC2,NRN1,FGF12,RASL10A,DLL3,GABRB3,MTHFD2,CPLX2,CPLX1,CSDC2,UBE2QL1,VSIG4,SYNPO,NEGR1,KCNN2,KCNN3,STXBP5,MAP4,MAPT,LRP1B,MN1,MX1,FXYD7,NCF2,NPTX2,NTRK2,KSR2,CNTN3,ENPP2,NALCN,SNX10,FXYD1,NKAIN4,PTX3,RASGRF2,CRTAC1,RGS4,RNASE1,KLHDC8A,FBXW7,MEG3,KCNIP3,STX1B,RYR3,SCN2B,FERMT1,NAPB,SNCA,MYO16,SPP1,SYN2,ZEB1,THRA,ENHO,PRRT1,CSMD1,TPM2,RBFOX3,P2RY12,ZNF711,CELF4,FSTL5,ANKS1B,JPH3" Coexpression M2697 Genes down-regulated in NCI-60 panel of cell lines with mutated TP53 [Gene ID=7157]. MSigDB C6: Oncogenic Signatures (v6.0) 2.27E-09 2.57E-05 3.90E-07 3.87E-06 51 192 "MTUS1,KCNAB2,GAS7,APOC1,APOC2,RGS20,ADAM23,BCHE,NRP2,ST3GAL5,CA12,CAPN3,SLC16A4,GAL3ST1,CPS1,ARHGEF10,VCAN,GREB1,ZFYVE16,RASSF2,GSDME,DOCK2,PLXNC1,NCALD,ST3GAL6,NSG1,CHL1,IFI16,L1CAM,MATK,MITF,TAGLN3,LYRM9,MYO5A,NEFM,NRCAM,PDE4B,LAMA1,ELOVL2,PTPN13,S100B,SGK1,ST8SIA1,SPP1,SPART,KANK1,TNS2,BEX4,VGF,VLDLR,NAV3" Coexpression 19139136-TableS3 Human Prostate_John-Aryankalayil09_2212genes GeneSigDB 3.12E-09 3.54E-05 5.29E-07 5.24E-06 246 1547 "RALGAPA1,ADCY6,BRAP,ADORA1,RNF150,ADRA1D,HECW2,OSBPL6,SPARCL1,BEGAIN,ANK2,PHF12,SHROOM2,IGDCC4,TMEFF1,ARRB1,CDK13,NCOA1,INSYN2B,ATP2A2,ATP6V0A1,KIF1A,BARD1,SEC11C,BLM,ST3GAL5,SYNJ2,IL33,PRC1,KYAT1,SCARB1,SYNGR3,TIGD7,CLGN,RCBTB2,SRSF11,CHN2,SLIT2,CPNE6,RAB33A,PPT2,FAM189A2,CCDC151,COL4A5,MAGED1,GAL3ST1,PREPL,RNF14,SIPA1L1,PDE4DIP,CNTNAP2,CTH,HDAC9,ARHGAP32,IP6K1,AIF1L,DNAL1,ARMCX2,MFAP3L,RUSC2,MTX3,RPS6KL1,CDON,SLC12A6,PDCD6IP,RCAN1,ARRDC4,ECM2,MAMLD1,E2F5,KLHL5,FRY,FSD1L,YAF2,EGFR,KMT5B,TNK2,CALCRL,PAN3,HSD17B14,RCAN2,CDKL3,ETV1,SIRPB1,ZNF461,DLC1,FDFT1,GORAB,FER,FGF1,FGF12,SCARA3,SEC23B,EFCAB2,JKAMP,SMC2,TPK1,PRELID3A,KHDRBS3,DLL3,MSANTD4,TPPP3,FYN,ZNF44,GABRB3,DENND2A,GAD1,TMEM8B,ACSS1,SRCAP,CYP46A1,GFER,GGT5,RAB30,KCNMB4,GNG4,FERMT2,ADGRA3,ATE1,PRDM5,CIT,FICD,HAS2,PADI2,NCKAP1L,SYNPO,HMGCR,HNF4G,SMAP1,ICA1,ZIC5,KNDC1,IL12A,STMN1,MAP2,MAP6,MBD1,MEF2C,MIA2,N6AMT1,MYH3,MYO5A,MYO9A,NCF2,PCBP3,NUCB2,CLDN11,PDE4B,GNG2,TMOD2,ABCB1,SERPINI1,PIK3C2A,TMIE,PIK3R1,RETREG1,XRN1,GPSM2,PMP22,TRHDE,TATDN3,PPP2R2C,PRKAB2,PRKAR1B,SLC26A11,HYDIN,PRODH,KLK6,LAMA1,WDR25,STK32A,PTPRN2,PTX3,MARCH1,ZNF793,SH3TC2,FAT4,GTDC1,PGBD4,NEK11,RTN1,CCDC112,RMI1,SARS,SBF1,MRAS,KIF27,SH3BGR,ARX,SYBU,FAM214B,ZNF334,EPC1,TTC17,FNBP1,ZHX3,ZSWIM8,KDM4C,UNC5B,ST5,MPRIP,ZSCAN29,ELOVL4,SEPT3,NSFL1C,SYNE2,SYT1,SLC37A2,TACC1,MCF2L,ADGRL3,ZEB1,TNS2,SIK3,ITGB3BP,NACC2,HEY1,CBX5,TMPO,BEX4,ANKRD24,NPL,PPIL6,TSC1,SGK3,FAM155A,UBE2H,CLEC2L,PLEKHH2,WNT7A,WRN,ZNF24,ZNF32,ZFP41,LYPD6,REEP1,ZNF189,SPIRE1,FTSJ1,DHX33,ZXDA,SEMA3B,PARP11,RGS7BP,MSRB3,FRMD6" Coexpression 18362358-Table7 Human Leukemia_Calln08_1020genes GeneSigDB 3.42E-09 3.89E-05 5.71E-07 5.67E-06 120 633 "USP31,INTS2,MTUS1,OSBPL8,SEMA6A,CDC42BPA,APBB2,USP37,CDC14B,SFMBT2,TMEFF1,NUMB,EIF4G3,ATP2A2,MTMR2,ZNF555,CALM1,CAST,MAGI1,CFL2,CHN2,RAB28,QKI,HECTD1,TBPL1,ENTPD4,RNF14,ARHGEF10,SOCS5,PDE4DIP,DZIP3,ARHGAP32,ZBTB24,MYEF2,MFAP3L,FBXL5,CDON,DMTF1,PHF20L1,KMT5B,KCTD3,PLEKHA1,TMEM35A,PAN3,USPL1,DLC1,FKTN,PRKAG2,SYNCRIP,RGPD5,JKAMP,NBEA,UFM1,GALC,ERAP1,TUBGCP4,GHR,MALT1,ZNF638,BVES,FRMD5,HSF2,IDH3A,KIF2A,IPO5,NCOA7,MBNL1,KCTD6,KITLG,NEK1,SLC11A2,NUCB2,OPA1,ZNF827,PFKFB2,CCSER2,RETREG1,PPM1B,PRKACB,PTCH1,PTPN13,PTPRG,RAD17,SLC25A36,PBRM1,RNASEL,ATXN7,ANKRD6,WDR47,SEPHS1,SLC12A2,LIMCH1,CMTR2,USP33,SOX11,ZC3H13,ARHGAP26,ITPRID2,NXT2,ELOVL4,NECAB1,PLCB1,SYT1,TCF12,ZFPM2,AP4E1,TIAM1,TRIO,AMACR,TRPS1,UBE3A,CLDND1,PCDH20,TRIM9,SPIRE1,UPF3A,SLC38A1,RNF103,RNF146,SOCS4" Coexpression 20436685-ST4-1 Human Breast_Pothuri10_811genes GeneSigDB 4.22E-09 4.79E-05 6.94E-07 6.88E-06 138 760 "AK2,BIN1,AMT,OGT,CDC42BPA,PKP4,APBB2,APOC1,LGR5,CDC14B,MARCH3,ADAM23,BID,MTMR3,CACNA1I,CA12,PRC1,LRBA,DCLK1,ZMYM4,ARHGAP22,PLAA,CLCN3,LY86,SLC4A8,C2CD2,CRYBB1,AATK,LRIG1,SOCS5,SLITRK5,KIAA0040,PUM1,GAPVD1,TCAF1,ZFYVE16,MAML1,DBI,MYEF2,MFAP3L,LYPD1,E2F5,RASGRP1,FRY,FAM13A,PLXNC1,VPS13B,ERBB4,NCALD,TLR7,DLC1,ST3GAL6,FER,SEC23B,SYNCRIP,ATP2C1,CELF1,FUT9,GAD1,ADAM28,CRCP,GNAL,GPR37,GRM8,FAM107A,IRF8,IPO5,SMAD1,MARK1,MATK,MBD1,MBNL1,MEF2C,MEIS1,MGAT3,ADAM22,OXTR,PFKFB3,PIK3R1,PLCL1,RETREG2,PRKACB,PKIA,MAPK9,BCAS3,SPDL1,PPP2R3C,RAD17,RBBP6,CRTAC1,SLC25A36,BAALC,MCMBP,MAP6D1,RPS20,RMI1,SCN2B,CASC3,SUPT20H,ZFP30,AMBRA1,FNDC3A,ST8SIA1,ANKRD6,WDR47,SLC12A2,SMARCA4,OGDHL,SOX3,TSNAXIP1,DOK5,UHRF1BP1L,UNC5B,RBM26,CLASP2,SEPT8,ZC3H4,ARHGEF9,ASTN2,CAMTA1,EXOC7,DNMBP,KLHL4,PHF24,DNAH7,SIRT1,UBE3A,BCL2L13,VIPR2,WIPF1,XRCC4,ATP6V0E2,NDRG4,SPHK2,TRIM16L,PARP11,PDSS2,ST8SIA2" Coexpression 21205295-TableS2 Mouse Viral_Buonomo11_116genes GeneSigDB 4.80E-09 5.45E-05 7.78E-07 7.72E-06 34 105 "ADRB2,DOC2A,APBA2,APLP1,BMP7,CACNA1A,HAP1,CDH2,SLIT2,CRMP1,HDAC9,SEMA3D,ERBB2,FGF1,OLFM1,FGFR1,FGFR3,CSPG5,DLL3,NEU3,CIT,KNDC1,LAMA2,MAPT,MYCN,MYO6,NF1,NOVA1,PTN,SCN8A,HES6,SOX11,HEY1,VLDLR" Coexpression M2446 Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.34E-09 7.21E-05 1.02E-06 1.01E-05 59 244 "ACADM,FMNL2,ZNF608,ARHGAP20,AMPD3,THSD7A,RUNX1T1,LDB2,SLC16A4,CDH2,DCLK1,RCBTB2,ZNF521,ZFP28,NR1D2,EDNRB,EYA1,MED12L,SCARA3,SESN1,RAB30,LPAR4,STMN2,IGF1,LRRCC1,IL6ST,KCND2,STMN1,LIFR,MAP2,MEF2C,MEIS2,MEST,KITLG,MMP16,NFIX,PCDH9,PIK3R1,PMP22,LRRN3,DIRAS2,PTPRD,PTX3,FAT4,TSPY26P,RNASEL,ZFHX4,DZIP1,SLC12A2,SLC14A1,MTERF2,ADHFE1,PLCB1,PDLIM2,TRIM2,ITGB3BP,TRPS1,PLEKHH2,ZIC1" Coexpression 19658189-TableS4 Human EmbryonicStemCell_Xu09_1801genes GeneSigDB 9.84E-09 1.12E-04 1.55E-06 1.54E-05 228 1430 "ASPHD1,XKR4,FMNL2,TMCC3,PLEKHH1,FZD9,UNC5A,PCDH19,OSBPL6,ZNF578,SEMA6A,UNC79,SYT13,PDZD4,APBA2,KCNAB2,CASK,TMEFF1,SPTBN4,TMEM108,STX16,ATP2A2,KIF1A,ADGRB1,BLM,PROM1,LDHD,GYG2,GPC2,CA4,CA12,RHBDL1,CBS,CLDN10,MTMR7,SLC16A4,CD86,SYNGR3,CD38,CDC25B,LARGE1,DLGAP1,CRLF1,NUMBL,NGEF,SULT4A1,ANKRD35,LETMD1,COL9A3,SLC4A8,GAL3ST1,RTTN,CRYBB1,CRYM,SIPA1L1,GALNT9,CNTNAP2,SLITRK5,PPP1R16B,CTH,ARHGEF4,RIMS2,RASSF2,DGKG,DAPK1,SPOCK2,PITPNC1,ELMO1,MFAP3L,KIF19,HS3ST2,CDON,DPYSL2,ARRDC4,DTNB,E2F5,SEZ6L2,HEYL,CELSR3,KMT5B,IRAK4,PCOLCE2,EPB41L2,EPHB1,SLC43A2,HSPA12B,TBC1D16,TUBB3,OLFM1,FGF13,FGFR1,BAIAP2,MAD2L2,SCARA3,HPCAL4,ZMYND15,SEMA4D,FLT1,DLL3,MPP6,GABBR1,GABRB3,GABRG2,MTHFD2,SYT17,ACSS1,GCNT2,GDF1,GLI2,CBX1,KIAA1958,GNG4,TDRKH,FUT10,STMN2,GRB10,DIDO1,CIT,GSTM5,SOX21,PSIP1,FAM107A,ACOT7,ZNF546,INSM1,KCNB1,KCND1,KCND2,KCNN1,KIT,CAMK2N2,MATK,MATN3,MBP,CHST6,MMP16,SAMD14,MX1,MYT1,NDP,NEFH,NELL2,NFIX,NFYA,NPY,NPTX1,NPTX2,NTRK3,PCDH8,PCSK1,PCSK5,ENPP2,PDPK1,PFKFB4,SEMA5B,SNX10,PSAT1,MAGEL2,EPB41L4B,PPP2R2B,PPP2R2C,HYDIN,PRODH,KLK6,LAMA1,STK32A,PTPRB,PTPRE,PTPRN,ZNF493,RASGRF2,RET,RNASE1,NUDT11,RORB,SNX22,NEK11,GLDN,EMID1,KCNIP1,RTN1,SALL1,LRFN5,HES6,GALNT10,PPM1E,FBXO11,MAST1,TRERF1,SOX3,NMNAT2,ZNF423,NFASC,SST,SSTR1,NXT2,STXBP1,KLHL7,RHBDL3,NUDT10,SYN2,SYP,SYPL1,COBL,PCDHGB7,SLC19A3,ARHGAP9,VWCE,TEK,ITGB3BP,SLC44A1,GALNT17,TIMP4,NPL,RPRM,UGT8,PLEKHH2,VGF,KLC2,KCNK12,ZIC2,TRIM9,GDPD5,HPS4,SLC17A7,KCNAB1,CPNE4,LAS1L" Coexpression M1999 The 'adult tissue stem' module: genes coordinately up-regulated in a compendium of adult tissue stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-08 1.14E-04 1.57E-06 1.55E-05 131 721 "ACTN1,NDRG2,ADCY6,ADRB2,OSBPL1A,SORCS2,TXNDC16,ALCAM,AMPD3,LGR5,ATP2A2,BACH1,MPDZ,DST,SGCE,CACNA2D1,CAMK2B,USP2,CDH2,ZMYM4,LRRFIP1,LARGE1,CACNA2D2,ABCG2,CNN3,CNTN1,COL9A3,MAGED1,ZNF521,ABCG1,CSF2RA,ARHGEF10,MYADM,ARHGAP32,DGKG,ARMCX2,DMD,CELSR3,EBI3,EIF1,RCAN2,DLC1,SEC24B,SLC9B2,FGF1,FHL1,EVL,NBEA,RASL10A,KHDRBS3,SARAF,FYN,GABBR1,GABRA3,GABRG1,GATM,SESN1,GLUL,FERMT2,ADGRA3,PCLO,GRIA2,PRDM5,HLF,ELOVL5,SYNPO,KCND2,KIT,KTN1,L1CAM,LAMA2,LMO2,SYTL4,SMAD1,MAP2,MATN2,MEIS1,KITLG,MITF,MMP17,PTOV1,TAGLN3,MYCN,MYH3,NCAM2,NFIX,NRCAM,SNX10,RETREG1,PMP22,EPB41L4B,PRKACB,PKIA,PRKCB,RELN,PTN,RGS4,ROBO1,ZFP30,NBPF1,SLC8A1,SLC12A2,ZFP1,GKAP1,LIMCH1,DBNDD2,THSD1,MPRIP,STXBP1,TAL1,PDLIM2,TCF4,ZFP90,PCDHB15,SIK3,TEK,AKTIP,NACC2,TK2,LRRC8A,BEX4,TP53BP1,TPM1,SSBP2,TTC3,VLDLR,ZNF23,ITM2C,PHTF2,ACTR3B,FRMD6" Coexpression 17724462-TableS2 Human StemCell_Nuytten08_2072genes GeneSigDB 1.14E-08 1.29E-04 1.75E-06 1.73E-05 270 1753 "ASIC1,ABHD6,METAP1D,ADD1,AXIN2,ADRB2,AGT,SORCS2,AK2,MARCH4,OGT,SEMA7A,PPFIA4,KCNAB2,EPB41L5,APOC1,USP37,CDC14B,RGS20,ASGR1,SLC4A4,ATP2A2,RNF182,AZGP1,BACH1,BLM,CFLAR,C5,CA12,PTBP2,CAST,SPAG9,PRC1,USP6,SLC16A4,SCARB1,SYNGR3,ENTPD6,NOG,CRLF1,UBE2L6,DIS3L,CFL2,FOXN3,B4GALT6,SLIT2,NRXN3,PPT2,QKI,MAP4K4,HOMER3,BAG4,NECTIN3,CPS1,ENTPD4,CSF1,CSF1R,SEC24C,ARHGEF10,SOCS5,PDE4DIP,DZIP3,KIAA0040,CTH,FAM131B,MYADM,CENPL,RASSF2,MATR3,KCTD8,DGKG,SPOCK2,PABPC5,GIT2,FAM107B,ARRDC4,TOM1,DNAJB6,ABCC5,FIS1,E2F6,EDN1,ANKRD46,OPTN,YAF2,FAM13A,EIF5,TMEM35A,ENO2,RABEPK,APC2,EZH1,ST3GAL6,FCGR3A,FGF1,OLFM1,BAIAP2,FHL1,POLK,AGAP3,ANKFY1,JKAMP,FAM49B,ATP2C1,CGREF1,DLL3,FYB1,TRAF3IP2,INPP5K,GCNT2,NFU1,GHR,MALT1,BRD8,TCERG1,MAP7D2,GPD2,TDRKH,GPR37,GRB10,DIDO1,ADAMTS6,HBA1,ZHX1,PACSIN2,BACH2,AGBL5,HP,CPT1C,IFI16,RBPJ,IL6R,IL6ST,FAM69A,JAK2,KCNB1,KHK,KPNA5,LAMP2,LIFR,LMO2,LSS,SMAD1,MAP2,MATN2,MATN3,MEIS2,MEST,MGAT3,KITLG,ZNF680,MSI1,MT1M,THYN1,MX1,MXI1,NBL1,NCF2,NFYA,NPTX1,OPA1,CLDN11,OXTR,PCDH9,PFKFB2,PFKFB4,SERPINI1,PKD1,ZFYVE21,XRN1,NLE1,PCDH18,PDZRN4,TRHDE,SCHIP1,EPB41L4B,PPM1B,PPP3CC,PRKAB2,CEP41,PKIA,RELN,SAMD9,PTK2,ZSCAN32,PTX3,QDPR,TMEM255A,SUSD4,RBBP6,REV3L,RGS4,SLC25A36,ZFHX4,ROBO1,PCMTD2,RPL15,SPIN3,KIAA0895L,RYR3,RMI1,SAFB,SCP2,TNFRSF19,MRAS,FAM214B,ZNF430,SLC12A2,ZNF334,NAPB,SLC22A4,CDK5RAP2,KIF13A,TMCC1,PDZRN3,GLT8D1,IZUMO4,CLASP2,MESP1,ZNF302,THSD1,SS18,NXT2,ELOVL4,RGL1,KLHL7,SYNE2,ARHGEF9,SYPL1,TBL1X,KLHL4,TCF4,ZEB1,SYNE1,TMEM121,ITGB3BP,SLC44A1,TK2,CBX5,LRRC8A,TMPO,CSMD1,TNS1,TP53BP2,TPM1,CDK20,NPL,TSN,TSC1,SSBP2,TUBB2A,HIRA,EIF4ENIF1,CCDC136,CCDC14,LAT2,XRCC4,PCDH20,ZNF177,DPYSL5,ANKS1B,DHX33,NAV3,PPP1R3F,NELFE,PDSS2,FBXO36,NLRP3,FRMD6,ST8SIA2" Coexpression M1941 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation at K4 (H3K4me2) and trimethylation at K27 (H3K27me3) in brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.28E-08 1.46E-04 1.94E-06 1.93E-05 179 1069 "KCNH8,NDRG2,ADORA2A,ADRA1D,ADRA1B,ADRB2,SLC24A4,MTUS1,SORCS2,SYT13,DPP10,VAT1L,CPNE5,LGR5,SFMBT2,PTCH2,CHRD,TMEM108,SLC4A4,ADGRB2,PROM1,BMP7,CA4,CABP7,CH25H,CBLN1,CBS,SYNGR3,ENTPD2,L3MBTL4,NOG,CACNA2D2,LHX2,IGDCC3,SEC31B,C1QL2,SNCAIP,RGS6,PLXNA4,AIF1L,ZNF804A,LYPD1,DLX1,HS3ST2,SLC29A4,DPP6,EBF1,EDN3,CNNM1,HEYL,EGFR,EGR3,EMX2,ERBB2,ADGRV1,EYA1,DLC1,PPP1R1B,FGF11,SPSB4,FGFR3,SCARA3,FOXF2,FLT1,PDLIM5,DLL3,MEGF11,GAD1,DISC1,PCDH17,GLI2,GNAL,GRIN2C,GRM8,FAM19A2,BVES,SOX21,ATOH8,IRAK3,NXPH3,TNFAIP8L3,SHISA6,IRF8,SOWAHA,ZIC5,SCIN,SLC6A17,ITGA7,C2CD4C,ITPKA,ITPKB,KCNF1,KCNH2,KIT,PIK3AP1,KITLG,PPM1L,MYCN,NBL1,NEFH,NFE2L2,NFIX,NPTX2,CLDN11,OXTR,P2RY1,PAX6,PCDH8,CDK18,PDE3A,PDE4A,PDE1B,SEMA5B,PLTP,PMP22,TRHDE,IRX1,PPARA,VSTM2L,DIRAS2,PRODH,RELN,LAMA1,STK32A,PTPRB,PTPRO,FAT4,RASGRF1,RASGRF2,CRTAC1,RET,FIGN,SNX22,GLDN,SALL1,MAPK12,SATB1,PEAR1,ARX,ASAP3,SHC4,ABLIM3,SLC6A11,SLC12A4,MAST1,INAVA,PDZRN3,MYO16,SOX3,UNC5B,SSTR1,ERBIN,STAC2,KANK1,SULF2,ADAMTS17,PDLIM2,SATB2,CHST8,CDH22,ICAM5,NR2E1,PIK3R5,TPM1,RPRM,MGAT5B,VGF,VIPR2,WNT7A,KCNK12,ZIC1,ZIC2,ELFN1,DPYSL5,SLC30A3,PRDM8,RGS7BP,DOCK8,ST8SIA2" Coexpression M2121 Genes correlated with classical type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.35E-08 1.53E-04 2.01E-06 2.00E-05 44 162 "SEMA6A,ABCD2,ARNTL,SLC4A4,BLM,CALM1,CAMK2B,CDH2,RGS6,OSBPL3,SIPA1L1,RASGRP1,EGFR,ERCC2,PIPOX,DLC1,FGFR3,DENND2A,GLI2,GRIK5,ITGA7,KCNF1,LMO2,MEIS1,NDP,PCSK5,PMP22,ELOVL2,ACSS3,RFX2,RGS12,ZFHX4,KLHDC8A,ZNF671,SEMA6D,SLC6A11,SLC12A4,KLHL4,WSCD1,NR2E1,HSPBP1,CLIP2,ZNF45,FZD3" Coexpression 16728581-SuppTable1 Human Liver_Capurso06_990genes GeneSigDB 1.43E-08 1.62E-04 2.11E-06 2.09E-05 160 932 "ACTN1,KDM5D,AXIN2,ALCAM,AMPD3,BIN1,LRFN1,OGT,ANK2,EPB41L5,APOC1,BCAS1,CDK10,ARRB2,ATP2A2,ATP2B2,ADAM23,ADGRB1,ADGRB2,BMP7,DST,SYNJ2,FUBP1,CACNA1A,DDR1,CAPN3,CBR1,ARHGAP33,LRRFIP1,MAGI1,NOG,MS4A7,RAB28,ABCG2,IQCK,ZNF521,HAPLN1,CSF1R,SIPA1L1,VCAN,SOCS5,PDE4DIP,CYBB,RIPOR2,HDAC4,TM9SF4,GIT2,MYEF2,KLHL3,MED12,RCAN1,EBF1,SUGP2,PLXNC1,TMEM132E,TENM1,RGS17,PCOLCE2,ELN,LRRC17,RASGRP2,RABEPK,IGSF6,RASL12,GMPR2,MRVI1,F5,CEP78,EVL,FOLR2,CGREF1,FYB1,GPR162,GGT5,LILRA2,ZNF496,RNFT2,MAP4K5,MUM1,IRAK3,HBA1,VSIG4,ACOT7,IL6ST,ITGA7,KLHL23,LMO2,GPR155,MEF2C,MEIS2,KITLG,MKLN1,MSR1,SAMD14,OGG1,PALM,PAX6,PFKFB3,PIK3R1,ZFYVE21,MTRF1L,PMP22,SEPT4,POU6F1,PPP3CA,PRKAR1B,PRKCB,MAPK3,ELOVL2,PID1,USP47,RBBP6,RGS12,MAP6D1,CLIP1,RMI1,MAPK12,GALNT10,FAM102A,FHOD3,ST8SIA1,SEPHS1,CDK5RAP3,ABTB1,SMARCC2,SMARCD3,SOX15,SP2,TROVE2,SST,SSTR2,PHLDB1,PRRC2C,TAL1,KIAA0930,RPGRIP1L,PHF24,ARHGAP9,SIK3,SIRT1,PARD3,TP53BP2,TPM2,DOK6,TRO,UBE2H,BCL2L13,RICTOR,ZBTB14,ZNF74,ANKS1B,ZFAND5,NT5M,SEMA3B,PCBP4,DOCK8,RTN4,UBE3B,JMJD1C,FXR1" Coexpression 19837975-TableS1 Human Leukemia_McWeeney10_885genes GeneSigDB 1.50E-08 1.71E-04 2.19E-06 2.17E-05 110 580 "KLHL13,TAOK1,FAM135A,GPRASP2,OGT,LCORL,APC,MPDZ,BMPR1B,CBFA2T2,TIGD7,B4GALT6,LY86,HOMER3,FAM171B,PDE4DIP,SLITRK5,HDAC9,RIPOR2,IST1,DAPK1,ARMCX4,ARMCX2,TIAM2,SPOCK3,RAB39B,DMD,USP3,ANKRD46,FEM1B,FSD1L,KMT5B,POLR1B,FHL1,NBEA,ATP6V1H,ZNF605,ZNF44,DISC1,FREM1,HPGDS,LNX1,PRDM5,GUCY1A1,GUCY1B1,IRAK3,HBA1,BACH2,HLF,HMGCR,KLHL23,STXBP5,LMO2,MAT2A,MEF2C,MEIS1,BEX5,NFYA,P2RY1,PCDH9,PDCD2,TMOD2,CCSER2,KANSL1,RASGEF1B,SLC26A11,PTPN13,PTPRE,RFX3,SLC25A36,CARF,ROBO1,MEG3,SATB1,FNIP1,KIF21A,SH3GL3,ANKRD6,SLC22A4,LIMCH1,TMCC1,FNBP1,SPP1,ZC3H13,ZBTB43,NKAIN2,CEP68,ANKRD28,TBCEL,TCF4,TCF12,ZMAT3,AKTIP,ARL10,TRPS1,SSBP2,TTC3,TUBB2A,ZNF17,ZNF23,MICU3,TCEAL7,ZBTB38,ZNF189,TMEM178A,TRIM16L,PLSCR4,RSPRY1,TTC7A,KLHDC1" Coexpression 17555561-Table1 Human Breast_Mackay07_1264GenesDownRegulated GeneSigDB 1.53E-08 1.73E-04 2.19E-06 2.18E-05 168 991 "ADORA1,USP31,INTS2,SEMA6A,CEP126,MAP4K3,PKP4,APLP1,LGR5,ARHGDIA,MARK4,ADAM15,AZGP1,ADGRB2,BCHE,RGS9,BCL7A,DST,MTMR3,MTMR2,BAIAP3,THSD7A,CALM1,PTBP2,PRC1,ZNF501,LRBA,DLGAP1,PPT2,CLTC,SULT4A1,HECTD1,SUMF2,COL9A1,CREM,ENTPD4,NCOR1,CS,CSF1,RGS6,CSNK1E,RIMS4,PDE4DIP,CNTNAP2,PUM1,FAM131B,DCAF8,TBC1D5,YTHDC1,JAKMIP2,ZC3H11A,DDX46,PARD6A,WDR20,HS3ST2,DYNC1I1,DTNB,TOM1,ABCC5,AASDH,SEZ6L2,TSPAN5,PHC2,FRY,PHF20L1,APH1A,EIF4G1,VPS13B,EPB41,MFSD10,PIPOX,CD320,OLFM1,FGFR1,IP6K2,PCYOX1,FOXO3,UFM1,STAU2,RAPGEF6,IQGAP2,SEPT9,SRCAP,GFRA2,RNPS1,POLL,PLCD4,CIT,COQ10A,IBA57,SLC6A17,NME9,KTN1,SFXN5,MAPT,GIT1,COL28A1,PTOV1,MYO5A,NFIX,NFYA,PCBP3,ZNF827,CNTN3,DPY19L2P2,PDPK1,DUSP26,PLXNB1,MBOAT7,FA2H,MAPK3,CNNM2,SNRK,ELOVL2,EML5,NKAIN1,QDPR,RBBP8,RGS12,ROBO2,MCMBP,HES6,SEC14L1,ZNF821,PUF60,SH3BP2,PEX26,SLC11A1,BTBD7,CPEB4,ZNF667,IFT122,LIMCH1,SNCA,SNRPN,KDM4B,DBNDD2,SPTAN1,RBM26,NFASC,SYT1,COBL,ANKRD12,TAF6,CRTC1,PCDHA6,FRYL,DICER1,ZFPM2,R3HDM1,PARD3,CABIN1,DOK6,HSPBP1,TTC3,SGK3,ZNF138,CELF4,DPYSL5,ZNF195,SH3GLB2,NT5M,DNALI1,PCBP4,PDSS2,ZNF37BP,TMEM63C,ST8SIA2" Coexpression 16293578-SuppTable2 Human StemCell_Cai06_1370genes GeneSigDB 1.55E-08 1.76E-04 2.20E-06 2.19E-05 195 1190 "ASIC1,NDRG2,ADORA1,MTA3,PCDH19,NME5,SRPX,SYT13,PDZD4,BIN1,LRCH2,PKP4,APLP1,CCDC74A,RASL11B,RNF182,ADAM23,ST3GAL5,CA4,CA12,CALB2,CAST,CLDN10,SEPT7,DCLK1,CRLF1,CFL2,FOXN3,CHN1,SLIT2,RAB26,CCDC151,CNTFR,CNTN1,IQCK,PCYT1B,COL4A5,SLC4A8,MAGED1,ZNF521,IGDCC3,CPS1,CLIP3,CRYM,LRIG1,CST3,CTH,DCAF4,BOC,LONRF1,PITPNC1,GSDME,RHOBTB1,FAM107B,DMD,DMPK,CD99L2,RPS6KL1,SLC29A4,RCAN1,DUSP9,TSPAN5,PHC2,MBNL2,CERCAM,RGS17,ERBB2,NCALD,APC2,RRAGB,OLFM1,POLR1B,SPSB4,FGF13,FGFR3,MAD2L2,FHL1,SCARA3,SEMA4D,TMEM175,TPK1,GABRB3,GAD1,TMEM8B,MTHFD2,SYT17,GATM,GPR162,FREM1,MALT1,RNPS1,GNG4,GP1BB,LPAR4,TMEM121B,STMN2,DIDO1,GSN,LINGO1,PSIP1,ATOH8,ICA1,NKD1,ZIC5,INPP1,KIFC3,MATN2,SCAMP5,TAGLN3,LAYN,NEFM,NNAT,NPY,NUCB2,PALM,PAX6,PCSK5,PDCD2,ENPP2,PIK3R1,JAKMIP1,PLTP,PMP22,NECAB2,EPB41L4B,PPM1B,LRRN3,PPP3CC,NKAIN4,PKIA,PRKCB,MAPK3,PRODH,PRPH,MASP1,ANKHD1,PTN,TMEM145,NKAIN1,PID1,FAM184A,ZMAT4,PRRT2,MORC4,RGS3,RGS4,BAALC,HSD11B1L,KCNIP1,CCDC112,LRFN5,TNFRSF19,FNDC3A,CCDC92,LIMS2,SEPHS1,TET1,CXXC4,ABTB1,SMARCD3,RCOR3,SNCA,SNRPN,TEX2,LARP4,RGL1,SULF2,VPS13A,COBL,TACC1,ADGRL3,SYNE1,TEK,SIRT1,GALNT17,ENHO,HEY1,ICAM5,TPM2,TTC3,FLRT2,VSNL1,WIPF1,KCNK12,ZIC2,TCEAL7,PROCA1,GDPD5,ADAMTS9,PCBP4,MPPE1,ST7,UBE3B,FRMD6,AP3B2" Coexpression M9808 Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO. MSigDB C7: Immunologic Signatures (v6.0) 1.66E-08 1.89E-04 2.33E-06 2.31E-05 50 197 "SEMA7A,KSR1,CD86,ARHGEF2,CACNA2D2,FBXO7,WHRN,CREM,NCOR2,LRIG1,PITPNC1,SV2B,FAM107B,EBF1,PLXNC1,GTF2IRD2,DCTN2,RAPGEF6,GNG4,PRRC2B,NXPH3,SYNPO,TTYH2,MATN2,SRSF12,AMZ2P1,NEFH,PDE4B,PDE4D,TMOD2,RETREG1,PCDHB17P,PKIA,TMEM145,RBBP6,ST6GALNAC6,KIF21A,SLC12A4,ATF7IP,KIF13A,GLT8D1,CEP68,ZC3H4,TAF6,TBL1X,TP53BP1,KCNE5,CLIP2,CLDND1,FXR1" Coexpression M8451 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.89E-08 2.15E-04 2.62E-06 2.60E-05 98 501 "XKR4,FMNL2,ESYT2,TAOK1,SRPX,CASK,ARHGDIA,STX16,BACH1,DST,CALB1,TPP1,AHCTF1,CREM,HAPLN1,DOCK4,HDAC9,TM9SF4,ZC3H11A,CPEB2,E2F5,EDIL3,ANKRD46,APH1A,MBNL2,EIF4G1,GPHN,FAM198B,SH3YL1,OLFM1,KHDRBS3,OGA,GALC,IQGAP2,ARFIP1,GFER,GLYR1,STMN2,GRB10,HAS2,UBE2QL1,MIER3,HNMT,IFI16,IL6ST,MAP2,MBNL1,KITLG,MMP16,ZNF92,MYO6,NF1,NFYA,PDE4B,GNG2,PMP22,MAPKAP1,PPP3CA,PRKACB,PKIA,PTPRB,PTPRO,PTX3,RASGRF1,GTDC1,RFX3,RGS4,SETD5,AP1AR,PPP4R3A,CCDC88A,SLC12A4,SLC14A1,CPEB4,BDP1,SPP1,MIR100HG,ITPRID2,NXT2,STX1A,ADGRL3,FBXW11,PCDHB15,ZMAT3,ENHO,TLR4,TRIO,DCBLD1,PLEKHH2,NDRG4,ZBTB38,SPIRE1,TUBA1A,NAV3,KAT6A,PHTF2,JMJD1C,FXR1" Coexpression 18199535-SuppTable1 Human StemCell_Amundson08_990genes GeneSigDB 2.11E-08 2.39E-04 2.88E-06 2.86E-05 159 930 "ACADM,ACHE,ADORA2A,ALCAM,AMPD3,AMPH,CDC42BPA,ANK2,APC,APOC2,SHROOM2,TMEFF1,ASPA,SLC4A4,RIPK1,AZGP1,BARD1,MPDZ,BCHE,SYNJ1,BTK,MTMR3,C5,RAB29,CAST,HIP1R,CBLN1,CLDN10,CCNT1,RGN,SEPT7,LARGE1,CDO1,CLGN,CACNA2D2,CFL2,CHRNA4,CPNE6,FAM189A2,ARHGEF6,CNR1,AKAP6,COL11A2,AKAP5,CPS1,CLOCK,CRMP1,CRYM,CSF1R,CSNK1G3,PDE4DIP,RUBCN,DAPK3,SACS,DYNC1I1,NR1D2,CASP8AP2,EDN3,EDNRA,HIPK3,EGR3,PLXNC1,RCAN2,ACSL4,FGF12,FOXF2,FLT1,FOLR2,STAMBP,GALC,IQGAP2,GPR162,CRCP,TCERG1,SPIN1,GLUL,RAB40B,GPD2,PTPRT,PSIP1,FAM107A,GUCY1A1,HSPA1L,ICA1,IFI16,IL6ST,KCNH2,MATN2,MBD1,MEF2C,MEIS1,AFDN,MMP16,MN1,MX1,MYO9A,NEK1,NF1,NFIX,NRCAM,NTRK3,OXTR,CDK18,PDE4A,PDE1B,PIK3R1,PLCB2,PMP22,SEPT4,POU6F1,PRKAB2,PKIA,MAPK4,RELN,PTH1R,PTN,PTPN13,PTPRD,PTPRN2,RBBP8,RDX,RET,REV3L,RGS3,RGS4,ROBO1,ATXN7,SCN8A,SUPT20H,HSPA4L,SH3BGR,SEC31A,SLA,SLC2A5,SLC12A2,SLC22A4,CPEB4,SNRPN,SPP1,TROVE2,FAM200B,TRIO,TSN,TSC2,SSBP2,UBE3A,USP1,VSNL1,XRCC4,ZNF23,ZNF177,ZNF184,WNK2,HNRNPA3,JMJD1C,FXR1,IFT88,AP3B2,ST8SIA2" Coexpression M2196 Genes significantly de-regulated (p < 0.05) by MIR21 [GeneID=406991] in A172 cells (glioma). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.33E-08 2.65E-04 3.15E-06 3.13E-05 65 289 "ESYT2,LCORL,APAF1,APC,MPDZ,LONRF2,SRSF11,FOXN3,HECTD1,CLOCK,HAPLN1,OSBPL3,GAPVD1,SCRN1,MYEF2,FBXL5,KLHL3,DDX46,DMD,RASGRP1,PHF20L1,PAN3,NBEA,SESN1,SPIN1,FERMT2,GPD2,CNTRL,LIFR,MEIS1,SAMD5,MYO9A,NEK1,PIK3C2A,PIK3R1,PPARA,MINDY2,PRKAB2,CEP97,USP47,REV3L,FIGN,PBRM1,ZNF532,CPEB3,FBXO11,ST6GAL1,BTBD3,BTBD7,TET1,ZNF667,LIMCH1,FNBP1,MYCBP2,SYNE2,VPS13A,ANKRD28,TACC1,TRIM2,TLR4,TPM1,CCDC14,ZBTB38,WNK3,RSPRY1" Coexpression 18537972-TableS2 Human Leukemia_San Jose-Eneriz08_1151genes GeneSigDB 2.61E-08 2.96E-04 3.48E-06 3.45E-05 163 962 "SYN3,ACHE,ADCY8,BRAP,OSBPL1A,C1QTNF3,DOC2A,CDC42BPA,APBB2,BCAS1,SEMA4G,MADD,ARHGDIG,PDE8B,ZSCAN18,BCHE,CFLAR,ARHGEF7,FUBP1,CA4,SLC25A14,CCK,MTMR7,CD86,ARHGEF2,NDST3,QKI,HOMER3,COL4A5,TBPL1,NCOR1,SNCAIP,OSBPL3,DZIP3,CTH,GREB1,ARHGEF4,KIAA0408,HDAC4,TM9SF4,TBC1D5,DAPK3,BRINP1,TIAM2,SGSM2,TMCC2,EXOG,DNM1,DMPK,EDNRB,KLHL5,CELSR3,PHF20L1,SUGP2,AASS,EIF4G2,IRAK4,TENM1,TNK2,ZNF391,ANKMY1,FAM198B,ZMYND10,FER,FGF12,TMEM164,FOXO3,POMT1,DISC1,INPP5K,LYVE1,PRRC2B,GRIA2,GSTM5,AP4S1,IRF8,FAM69A,INPP5B,KCNQ3,PACRG,PTOV1,TAGLN3,MYT1,FXYD7,NFIX,NOVA1,NTRK2,NTRK3,SETD4,OCRL,PCDHGC3,PDE4A,GPR173,PFKFB4,ABCB1,PIK3R1,MTRF1L,MAPKAP1,PPP3CC,MASP1,BCAS3,APTX,TMEM104,PTCH1,SPDL1,PTN,PTPRD,CCDC40,RAP1GDS1,RBBP6,GAL3ST4,RGS12,S100B,DZIP1,SLC12A2,ATF7IP,SMARCA4,SNAP25,KIF13A,KDM4B,FNBP1,ZSWIM8,UNC5B,ZNF423,DBNDD2,SPTAN1,SPTB,SEPT8,JMJD6,ARHGEF9,PLCB1,TACR1,TAF6,IQCE,WSCD1,TCF4,SATB2,ZEB1,PUM2,CRTC1,PCDHA5,SLC35G2,SIK3,PMS2CL,NACC2,ACTR6,SMUG1,TRIO,PDSS1,TSC2,UBE3A,USP1,VIPR2,ZNF23,TRIM9,ZNF45,SPHK2,ANKS1B,EVI5,RNF103,ADAMTS9,SEMA3B,SENP7" Coexpression M4584 Genes up-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.82E-08 3.20E-04 3.72E-06 3.69E-05 50 200 "OSBPL1A,ALCAM,LCORL,MAP4K3,SFMBT2,SYNJ2,CCNH,ABCG2,ZFYVE16,DGKG,PITPNC1,SACS,NR1D2,GPHN,PIPOX,EZH1,ARMCX1,FGF13,SYNCRIP,NSG1,RAPGEF6,INPP5K,PRDM5,ICA1,KIF2A,SYTL4,SMAD1,MAT2A,MBNL1,NEFH,NFIX,CNOT4,EPB41L4B,PRKACB,PRPSAP2,RBBP8,CLIP1,HKDC1,TET1,FAM126B,ERBIN,ANKRD28,TCF4,SLC44A1,THRA,TNS1,UCHL1,SLC30A4,ST7,FRMD6" Coexpression M17923 "Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.85E-08 3.24E-04 3.72E-06 3.69E-05 86 425 "NDRG2,MTUS1,C1QTNF3,ALCAM,SRPX,LTBP4,ANK2,GAS7,APOC1,ASPA,ZBTB10,N4BP2L1,BCHE,IL33,RUNX1T1,CBS,CDH2,DCLK1,CDO1,CRLF1,COL4A5,ABI3BP,HAPLN1,GSDME,RHOBTB1,CHRDL1,DNM1,ECM2,EDNRB,FAM13A,EGFR,EIF5,TENM1,EIF1,RASL12,FLNC,PDLIM5,ERAP1,GGT5,GSN,GUCY1A1,GUCY1B1,HLF,ELOVL5,SYNPO,IGF1,IL6R,MARK1,MATN2,LRP1B,MITF,ADAM22,MT1M,MX1,HNRNPM,NELL2,NINJ2,NOVA1,NTRK2,OXTR,PFKFB3,PIK3R1,FXYD1,PLTP,PSAT1,ELOVL2,PTPRD,PTPRO,RAP1GDS1,RGS4,ATP8B4,RPS6KA2,SHMT2,ANKRD36,LIMCH1,DOK5,LMO3,NACC2,TIMP4,TMPO,TP53BP2,TPM2,UCHL1,SLC38A1,KCNAB1,ADAMTSL3" Coexpression 15273739-SuppTable2 Human Intestine_Jinawath04_1553genes GeneSigDB 3.21E-08 3.65E-04 4.15E-06 4.11E-05 190 1164 "ABHD6,ADRA1D,ADRA1B,CASKIN1,SRPX,CDC42BPA,EP400,APBB2,NT5C3B,AQP6,CDC14B,MADD,CDK13,EIF4G3,ZNF582,ATP6V0A1,ADAM15,SEC11C,BCHE,ZNF599,CFLAR,SYNJ1,C5,KALRN,SLC25A14,CARS,HIP1R,RHBDL1,ENTPD2,MAGI1,COPB2,QKI,HECTD1,COL9A1,MYRIP,NECTIN3,CDC42BPB,ANKRD44,NCOR1,CSF2RA,OSBPL3,SIPA1L1,FAM131B,DOCK4,HDAC9,DGKG,C2CD2L,RHOBTB1,USP3,SEZ6L2,EDNRA,FRY,KMT5B,TUBD1,EPB41,MFSD10,VPS26C,RRAGB,EZH1,CLVS1,FAM198B,CEP78,FER,FOXO3,SPECC1,PDLIM5,CAMKK2,STAU2,SDCBP2,GABBR1,FAM120B,ACSS1,ARFIP1,GFRA2,PCDH17,CSDC2,HTATSF1,MAP7D2,GNAL,GPER1,GRIN2D,GRM8,GSN,GSTT2,HBA1,HMGCL,CPT1C,DHX35,ITPKB,KCNJ16,KPNA5,LIMS1,LSS,ASPRV1,SMAD1,MAP6,MBP,ADAM11,MEIS1,MEIS2,KITLG,AFDN,DBNL,MX1,MYH3,NUCB2,P2RY1,PCDH9,PCSK1,PDE3A,PDE4A,SERPINI1,PIK3R1,KCTD15,SEPT4,PPARA,PPP1R1A,LRRN3,PPP3CC,PPP5C,CEP41,MAPK3,MAPK9,NKAIN1,RASGRF1,RDX,RET,RNASE1,ZFHX4,SETD5,HSD11B1L,KCNIP3,RXRA,ZNF331,SCN2B,GALNT10,SGK1,FAM102A,ST8SIA1,SLC6A8,ARHGEF40,ATF7IP,SLC22A4,CPEB4,ARFGAP1,TTC17,ZNF415,MYO16,USP33,ARHGAP26,ZBTB43,NFASC,LMO3,POGZ,ERBIN,ST5,VPS13A,CAMTA1,DNMBP,TAL1,TNS2,PCDHA6,RNF175,THRA,TK2,PRRT1,CSMD1,TPM1,TPM2,WBP2,PPIL6,TSC2,TST,TTC3,UGT8,CCDC14,VSNL1,CLIP2,KCNT2,TRIM9,MAP3K12,STOX2,RNF103,SEMA3B,MDH1B,SNX14,IFT88,DPF3,SPATA13,SENP7" Coexpression M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.47E-08 3.94E-04 4.42E-06 4.39E-05 94 480 "C1QTNF1,SRPX,ANK2,KSR1,DST,JAZF1,SGCE,IL33,CCK,CFL2,SRSF11,CHN1,ANKRD35,COL9A1,CNRIP1,AKAP12,GPRASP1,SCRN1,ARMCX4,HEPH,CHRDL1,DMD,DTNA,OPTN,TMEM35A,ENO2,RCAN2,SPEG,RASL12,MRVI1,FGFR1,FHL1,FLNC,C2orf88,FYN,GATM,TNRC6A,GNAL,FERMT2,BTN2A1,UBE2QL1,HLF,INPP1,KIT,LSAMP,GPR155,MEIS1,KITLG,LAYN,NBL1,NEFH,NELL2,NPR2,ZNF827,PCDH9,PDE4A,PIK3R1,PLCL1,PMP22,PPP3CC,MASP1,BEND5,PRRT2,PRIMA1,PNMA8A,ROBO1,KIRREL1,MEG3,SEMA6D,GALNT10,MRAS,FHOD3,PREX2,ARHGEF40,SLC14A1,INAVA,UNC5B,MIR100HG,ST5,TACC1,GPR161,ARL10,TNS1,TPM1,TPM2,SYNPO2,TRO,PLEKHH2,CCDC136,TMEM237,STOX2,TUBA1A,MSRB3,FRMD6" Coexpression M8702 Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.50E-08 3.98E-04 4.42E-06 4.39E-05 69 317 "ADRB2,MTUS1,SPOP,BACH1,BCL7A,DST,ARHGEF7,USP6,CBFA2T2,QKI,RCHY1,PUM1,USP6NL,DOCK4,GAPVD1,MAML1,ZBTB24,SACS,DMTF1,E2F5,PHC2,FEM1B,VPS13B,SUCO,FOXO3,FYN,ZNF44,AHDC1,BRD8,ZNF638,FERMT2,DIDO1,RBPJ,KIF2A,MEIS1,AFF1,MN1,NFE2L2,CNOT4,PTK2,REV3L,SLC25A36,SATB1,CPEB3,CHD9,FNDC3A,WDR37,BTBD3,TMCC1,DOP1A,GLT8D1,POGZ,KANK1,ZC3H4,PRRC2C,VPS13A,MTCL1,CLASP1,DOCK9,PUM2,FRYL,KAT6B,SSBP2,FLRT2,USP1,VLDLR,XPO1,NAV3,KAT6A" Coexpression M2324 Genes up-regulated in uterus upon knockout of BMP2 [GeneID=650]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.17E-08 4.74E-04 5.21E-06 5.16E-05 132 745 "NDRG2,KLHL32,ADCY6,TMCC3,AXIN2,RNF150,ZNF608,KIAA1324,SORCS2,ALCAM,LTBP4,AMPD3,SMIM29,ATP2B2,BCHE,GPR146,PROM1,BMP7,RAB29,CA12,DDR1,CALB1,CAST,CLDN10,SCARB1,FAM189A2,ZNF521,CRY2,GDA,CLIP3,SNCAIP,LRIG1,KIAA0040,GREB1,RIPOR2,DCAF8,DAPK1,SCRN1,SPOCK2,IP6K1,RHOBTB1,SV2B,DMPK,NR1D2,EDNRA,VPS13B,LRRC17,NCALD,MRVI1,HSPA12B,F5,SH3YL1,TMEM132C,ACSL4,PTK2B,FCGRT,SPSB4,IP6K2,FOXO3,AFF2,HVCN1,FUT9,GAA,GALNT15,HIGD1B,CPLX2,SESN1,GGT5,GHR,PARD3B,GSTT2,FAM107A,GUCY1A1,JAK2,SLC35G1,KCND2,LAMA2,LMO2,SMAD1,MATN2,MEIS2,MYCN,NBL1,NNAT,NPR2,NTRK2,OXTR,P2RX7,ENPP2,GNG2,ABCB1,PIK3R1,FXYD1,SLC25A23,PLTP,SEPT4,PRKAR1B,GDPD1,SNRK,PTH1R,PTPRB,PTPRD,REV3L,RGS3,RNASEL,SATB1,CSRNP3,SCN7A,SH3BGR,PPM1E,KIF16B,RADIL,INAVA,FNBP1,SPP1,ADHFE1,PHLDB1,PDLIM2,TEK,THRA,FAM124A,RASD2,SYNPO2,TRPS1,RUSC1,CCDC136,VLDLR,NPDC1,KCNAB1,ITM2C,PLSCR4,MSRB3" Coexpression 20421987-TableS1 Human Lung_Hou10_1067genes GeneSigDB 4.27E-08 4.85E-04 5.27E-06 5.22E-05 129 724 "NCKAP5,CCDC85A,ADRB2,HECW2,ADGRF5,SPARCL1,SEMA6A,SRPX,ARRB1,ASPA,TMEM108,DOCK11,CFLAR,DST,IL33,CA4,CAPN3,PRC1,LDB2,LRRFIP1,CDO1,CACNA2D2,CFL2,MS4A7,SLIT2,FAM189A2,QKI,FHL5,ARHGEF6,CNR1,ABI3BP,AKAP12,ANKRD44,ARHGEF10,DOCK4,MYADM,RASSF2,DAPK1,SPOCK2,CHRDL1,DMD,DPYSL2,ECM2,EDN1,EDNRA,EDNRB,FRY,PCOLCE2,CALCRL,EIF1,ERBB4,HSPA12B,F8,ABCA8,DLC1,FHL1,FOXF2,ATP13A4,HIGD1B,GHR,LYVE1,HPGDS,FERMT2,GPT2,LILRA2,TPPP,FAM107A,GUCY1A1,IRAK3,HBA1,TOX2,HLF,VSIG4,NEGR1,IL6R,IL6ST,KCNK3,LAMA2,LIFR,LMO2,MSR1,MT1M,NTRK3,PCDH9,PMP22,PSAT1,PTPRB,PTPRG,ACSS3,FAM184A,RASGRF1,CRTAC1,RFX2,ROBO2,GLDN,RPS6KA2,LRRK2,SCN7A,SH3GL3,PREX2,PKNOX2,SLC11A1,SLC14A1,SLC22A4,LIMCH1,PDZD2,SPP1,TACC1,TAL1,PDLIM2,SYNE1,DOCK9,TEK,ZFPM2,NACC2,TLR4,TMPO,TNS1,PIK3R5,SYNPO2,PLEKHH2,KCNT2,ZFAND5,ADAMTS9,PLSCR4,FAM13C,ADAMTSL3,MSRB3,NHSL1" Coexpression 15902281-TableS1d Human Leukemia_Schoch05_1441genes GeneSigDB 4.60E-08 5.23E-04 5.62E-06 5.57E-05 109 585 "ACHE,FZD9,AMPH,CDK13,AZGP1,SGCE,CACNA2D1,THSD7A,CAMK2B,DGKI,AP4M1,SEPT7,TBRG4,ASIC3,CHN2,SUMF2,OSBPL3,CNTNAP2,PHF14,FAM131B,DOCK4,HDAC9,TCAF1,INTS1,DGKB,SCRN1,ELMO1,GSDME,POM121,DYNC1I1,DMTF1,DPP6,DNAJB6,FIS1,SEMA3D,EGFR,RASA4,AASS,ELN,STARD3NL,LRRC17,MTSS1L,ETV1,PRKAG2,FLNC,TPK1,MPP6,DENND2A,GCK,CRCP,DBF4,GPER1,GPR37,PCLO,GRB10,GRM8,ICA1,SCIN,KCND2,KCNH2,MEST,MKLN1,ADAM22,ZNF862,CNOT4,NPY,NPTX2,NRCAM,PDE1C,GPR85,PGAM2,ABCB1,SNX10,ING3,PILRA,LRRN3,CEP41,PRKAR1B,RELN,SAMD9,PTN,PTPRN2,ZCWPW1,ZDHHC4,SMARCD3,SP4,HECW1,PEG10,STX1A,KLHL7,SYPL1,COBL,TAF6,IQCE,PMS2CL,GALNT17,RUNDC3B,ZKSCAN5,UBE2H,VGF,VIPR2,CLIP2,LAT2,ATP6V0E2,ZNF138,SLC30A3,ST7,PHTF2,ACTR3B" Coexpression 15489324-TableS2 Human Messina_04_1962genes_TranscriptionFactors GeneSigDB 4.67E-08 5.31E-04 5.65E-06 5.60E-05 265 1741 "KDM5D,KLHL13,ZNF687,ZFAT,EP400,CASK,ARNTL,ZSCAN18,ZBTB10,NCOA1,ZNF582,ZNF583,BACH1,ZNF599,FUBP1,ZNF555,KALRN,RUNX1T1,LDB2,CBFA2T2,ZMYM4,ZNF445,FOXN3,CNOT8,LHX2,VAX2,FHL5,TBPL1,SMARCAL1,ZNF521,ZFP28,CLOCK,CREM,RNF14,NCOR1,NCOR2,TRIM69,KIAA0040,GREB1,HDAC4,ZNF337,ZBTB24,KLHL3,DLX1,MED12,NR1D2,DMTF1,MAMLD1,E2F5,E2F6,EBF1,HEYL,KLHL5,OPTN,YAF2,MBNL2,KMT5B,EGR3,EMX2,ERCC2,DENND4A,NCALD,ZNF549,ETV1,EYA1,EZH1,ZNF461,ZNF585B,SCML2,ZNF589,GTF2IRD2,FHL1,FOXF2,FOXO3,AFF2,TMEM175,PDLIM5,TRIM16,ZNF44,ZNF274,ZNF559,SRCAP,PPARGC1A,ZNF276,TCERG1,GLI2,TOX3,TNRC6A,CBX1,STON1,TMEM121B,DIDO1,PRDM5,ZNF496,ZBTB49,ZBTB45,SOX21,PSIP1,ATOH8,ZHX1,BACH2,MIER3,HLF,HNF4G,ZNF491,HSF2,IRF8,ZIC5,RBPJ,INSM1,LMO2,SMAD1,SMAD9,MBD1,MEF2C,MEIS1,MEIS2,MID1,MITF,AFF1,AFDN,ZNF92,MXI1,MYCN,ZNF862,MYT1,NFE2L2,NFIX,NFYA,CNOT4,SETD4,ZNF713,ZNF827,PAX6,ZNF655,ZNF426,POU6F1,IRX1,PPARA,ZSCAN32,ZSCAN2,ZNF615,ZNF493,HKR1,TRIM68,DPF2,REV3L,RFX2,RFX3,ZFHX4,ZNF532,RORB,ZNF671,KCNIP3,KCNIP1,ZNF354C,RXRA,ZNF568,ZNF331,SAFB,SALL1,SATB1,ATXN2,HES6,ZFP2,SUPT20H,ZFP30,ARX,BTBD3,PKNOX2,ZNF430,KDM4D,ZNF334,ATF7IP,ZKSCAN3,ZFP1,SMARCA4,SMARCC2,DMRTC1,RCOR3,ZNF415,KDM4B,TRERF1,SOX3,SOX11,SOX15,KDM3A,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,LMO3,ZNF621,MESP1,ZNF302,MPRIP,ZSCAN29,SUPT5H,ARC,TAF6,TAF9,TAL1,KLHL4,ATMIN,TCF4,SIN3B,SATB2,CUX2,ZEB1,TCF12,HIF3A,ZFPM2,ZNF106,THRA,NACC2,HEY1,CBX5,NR2E1,TP53BP2,NR2C2,METTL3,TRPS1,ZKSCAN5,HIRA,ZNF610,UBTF,ZFP37,ZBTB14,ZIC1,ZIC2,ZNF711,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,TRIM9,ZNF45,ZNF540,ZNF74,ZNF138,ZNF142,ZNF154,ZNF177,ZNF184,ZSCAN26,ZNF189,ZNF195,ZNF213,ZFAND5,SMARCAD1,MEIS3,ZNF225,ZXDA,PRDM8,PRDM10,RNF103,JMJD1C,DPF3,ZNF30,LAS1L" Coexpression M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.95E-08 5.63E-04 5.92E-06 5.87E-05 86 430 "ABHD6,NCKAP5,TMEM132B,KLHL13,ALK,TRMT9B,PPFIA3,IGDCC4,PLA2G4C,ATP1A1,ALDH7A1,GYG2,C5,KALRN,LDB2,SLIT2,ARHGEF6,AKAP7,CREM,HDAC9,DAPK1,BRINP1,SV2B,FAM107B,DMD,EDNRA,EPHB1,FCGRT,HVCN1,CSPG5,AP4B1,GFRA2,FREM1,PCDH17,MAP7D2,GPD2,GPR37,GRIA2,LINGO1,TOX2,PADI2,IGF1,SCIN,ITGAM,KCNK3,KIT,LMO2,MAPT,TM6SF1,MEIS1,POC1B,SAMD5,NELL2,NPTX2,NRCAM,PCDH9,CYTL1,PIK3R1,TRHDE,LRRN3,PRKCB,RELN,PTPN13,MARCH1,FAT4,NUDT11,MRAP2,STK32B,SEMA6D,CSRNP3,LRFN5,SEC14L1,SH3GL3,ST6GAL1,FNBP1,SPP1,ZC3H13,LMO3,CLSTN2,TCF4,TCF12,TSPAN11,ZNF711,REEP1,SLC17A7,SPATA13" Coexpression 18614019-TableS4c Mouse StemCell_Fazzio08_2031genes GeneSigDB 5.22E-08 5.93E-04 6.18E-06 6.12E-05 199 1239 "ABHD6,EMILIN3,NCKAP5,TMCC3,AXIN2,HECW2,PCDH19,ALCAM,ALK,BIN1,SEMA7A,MAGEE2,VAT1L,BCAS1,USP37,CPNE5,MARCH3,NCOA1,ATP2B2,KSR1,DST,WASF1,IL33,CALB1,KALRN,PTBP2,SLC25A14,CAPN3,CH25H,NFS1,METTL6,DLGAP2,DLGAP1,LHX2,VAX2,SULT4A1,CNGA3,TBPL1,IGDCC3,SLC35F1,FAM171B,C2CD2,CRHBP,SNCAIP,LRRC3B,PDE4DIP,PHACTR3,CNTNAP2,PLXNA4,RASGEF1C,FAM131B,CYBB,DOCK4,TBC1D5,KCTD8,BRINP1,SPATA2,TIAM2,MFAP3L,C2CD2L,TMEM130,RHOBTB1,FAM107B,DMD,DYNC1I1,CPEB2,ECM2,DNAJB6,ABCC5,PHC2,FEM1B,EEF1D,PLXNC1,AASS,PCOLCE2,RCAN2,LRRC17,SCML2,FGF1,FGF13,BAIAP2,AGAP2,FLNC,ATP13A4,FLT1,PDLIM5,TPPP3,ZMAT1,MEGF11,DISC1,IGSF5,PCDH17,CBX1,GPD1,PCLO,ATE1,GSN,BVES,FICD,RASSF8,NCKAP1L,GABARAPL2,MYLK2,NKD1,SCIN,FAM69A,KCNN2,STXBP5,ASPRV1,EFHB,MEIS2,MMP17,MYCN,MYH3,NBL1,NEFM,NEFH,NINJ2,NPY,NPTX2,TREM2,PCDH8,PCSK5,DUSP26,PLCL1,PURG,MAGEL2,SEPT4,SH3KBP1,IRX1,PPP2R2B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,SKOR1,HYDIN,RELN,SNRK,PTPN13,PTPRD,PTPRE,PTPRG,PTPRO,RIPOR1,MARCH1,ZCWPW1,ZMAT4,TRIM68,KLHL11,ROBO1,LRRK2,RXRA,RYR3,CSRNP3,SMPD3,GALNT10,PREX2,SLC6A8,EPC1,INTS9,LIMCH1,PDZRN3,ZHX3,UNC5B,ZC3H13,CDK19,SPART,CLSTN2,THSD1,APOM,ZC3H4,RHBDL3,PLCB1,SYN2,ALG1,ADGRL3,DOCK9,ZNF106,RIMBP2,PARD3,TNS1,IL34,SYNPO2,DCBLD1,UBC,FLRT2,LYPD6,FSTL5,DPYSL5,ZFAND5,DHX33,TMEM178A,EPM2A,FZD3,TMEM63C,JMJD1C,NETO2,DPF3" Coexpression M2775 "Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi." MSigDB C6: Oncogenic Signatures (v6.0) 5.71E-08 6.49E-04 6.69E-06 6.63E-05 40 147 "ASPHD1,GAS7,SLC4A4,PROM1,CH25H,SLC16A4,CRLF1,UBE2L6,COL9A3,SEC31B,CREM,CLIP3,EDN3,REEP2,FCGRT,PDLIM5,CHL1,PPARGC1A,STON1,ITGA7,KCNJ16,NEFH,PCDH8,PCSK1,PDE3A,PDE4B,CYTL1,SERPINI1,C1orf54,PNMA8A,KANSL3,OGDHL,DOK5,NMNAT2,ZNF423,LMO3,CUX2,TRIM2,NR2E1,EVI5" Coexpression 15902281-TableS1e Human Leukemia_Schoch05_1374genes GeneSigDB 6.01E-08 6.83E-04 6.97E-06 6.91E-05 108 581 "ADRA1B,ADRB2,NME5,C1QTNF3,SEMA6A,APC,PDE8B,ALDH7A1,CAMK2A,CAST,CCNH,CDO1,CNOT8,CLTB,NRG2,CRHBP,HAPLN1,RNF14,SNCAIP,CSF1R,CSNK1G3,VCAN,FAM169A,ZFYVE16,MATR3,MAML1,DBN1,JAKMIP2,KLHL3,DDX46,DOCK2,EDIL3,DCTN4,CDKL3,REEP2,RACK1,FER,FGF1,POLK,FYB1,MEGF10,GABRG2,IQGAP2,ERAP1,CPLX2,GDF9,GHR,BRD8,TCERG1,TPPP,ADAMTS6,SYNPO,HMGCR,IL6ST,KCNN2,KIF2A,LIFR,MEF2C,PCDHGC3,PCSK1,PDE4D,PIK3R1,RETREG1,IRX1,PCDHB17P,MAPK9,ANKHD1,SPDL1,RAD17,SH3TC2,KCNIP1,ZNF354C,FNIP1,ZFP2,GALNT10,ABLIM3,SLC12A2,SLC22A4,PDZD2,BDP1,ARHGAP26,ATP10B,ERBIN,SEPT8,TAF9,FBXW11,PCDHGC5,PCDHGB6,PCDHGA11,PCDHGA10,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,NSD1,PCDHAC2,PCDHA6,PCDHA5,PCDHA3,PCDHA2,TRIO,AMACR,SSBP2,XRCC4,TIGD6" Coexpression 19286929-SuppTable2q Mouse Lung_Rangasamy09_1540genes GeneSigDB 6.09E-08 6.91E-04 6.98E-06 6.92E-05 163 974 "ABHD6,CCDC85A,GALNT13,MTUS1,KLHL13,CC2D2A,ABCD2,OGT,DDO,TMEFF1,PDE8B,ASPA,DYNLL1,EIF4G3,IL33,CALB1,PTBP2,ARHGEF25,LRRFIP1,DIS3L,RCBTB2,CHN2,NGEF,ARHGEF6,CPS1,SNCAIP,PDE4DIP,GREB1,TCAF1,PABPC5,ARMCX4,ARMCX2,MFAP3L,DTNA,ECM2,PHF20L1,KMT5B,STX2,SRRM1,NCALD,VPS26C,EYA1,GMPR2,EZH1,ARMCX1,FAM198B,TMEM132C,ST3GAL6,CEP78,POLK,HPCAL4,EVL,JKAMP,PDLIM5,FUT9,FYB1,ZMAT1,GABRG1,GAD1,FAM120B,GATM,PCDH17,GHR,TOX3,MSL3,CBX1,MUM1,NCKAP1L,MIER3,HNMT,AGFG1,IRF8,METTL21A,KLHL23,STXBP5,LIG4,LMO2,MBNL1,CHIC1,TM6SF1,MGAT3,SAMD5,NNAT,NPTX1,SMIM11A,OCRL,PCSK5,PLXNB1,PURG,ING3,POLG,PTCH1,ZIK1,TTC13,FAT4,RBBP6,GTDC1,RFX3,DCUN1D2,TMLHE,ROBO1,ROBO2,ADAL,RPS6KA2,ATAT1,SEMA6D,SUPT20H,TRA2B,ZFP30,CHD9,ST6GAL1,DZIP1,PEX26,CCDC88A,MTERF2,EPC1,CXXC4,INTS9,RCOR3,MBD5,FAM126B,PDZD2,KDM4C,DBNDD2,TROVE2,ST5,SULF2,SYNE2,VPS13A,SYN2,ASTN2,ANKRD12,TAF9,SMG6,NSD1,ZMAT3,CBX5,ANKRD24,R3HDM1,SYNPO2,METTL3,STXBP4,TRPM2,DCBLD1,TSC1,SSBP2,TTC3,PRR18,VSNL1,WRN,XPO1,AMZ1,FSTL5,ANKS1B,FTSJ1,ZFAND5,INTS3,PRDM8,MPPE1,FAM13C,ST8SIA2,SPATA13,SENP7" Coexpression 18614019-TableS4b Mouse StemCell_Fazzio08_466genes GeneSigDB 6.43E-08 7.30E-04 7.30E-06 7.24E-05 67 309 "MTA3,MTUS1,WDR35,PDZD4,PPFIA4,APC,SFMBT2,IGDCC4,ZBTB10,BCL7A,PTBP2,ARHGEF25,LRRFIP1,MAGI1,CLIP3,CSNK1E,DCAF8,DBN1,PITPNC1,MFAP3L,DMPK,DTNA,SLC43A2,EYA1,POLK,ZBED3,TRAF3IP2,TOX3,DCLK2,GPT2,GRB10,HAS2,CELF5,MSL1,MID1,AFDN,NRBP2,NNAT,P2RX7,KCTD15,RAP1GDS1,FIGN,SLC25A36,LGI2,MEG3,SALL1,HES6,CHD9,ST8SIA1,TRIM67,SMARCC2,IFT122,KIF13A,SOX11,JMJD6,WSCD1,PCDHGA11,ZMAT3,ANKRD24,TRIO,TRO,TRPS1,RPRM,WIPF1,MAP3K12,SLC38A1,RNF170" Coexpression 16288009-SuppTable2 Human StemCell_Moreno05_297genes GeneSigDB 7.14E-08 8.11E-04 8.03E-06 7.96E-05 60 266 "BBOX1,PLA2G4C,ATP1B3,ATP2A2,ADAM23,ADGRB2,BLM,CALM1,HIP1R,CDH2,DCLK1,CLGN,CNN3,IQCK,CABP1,COL4A5,NECTIN3,CREM,CLIP3,LRIG1,VCAN,ZNF804A,MFAP3L,SPOCK3,RCAN1,ENO2,RCAN2,ETV1,OLFM1,FGFR1,UBE2E3,CSPG5,FUT9,MTHFD2,SYT17,HTATSF1,GP1BB,HLF,KCNK3,ADAM22,NBL1,NNAT,NPTX2,CDK18,LRRN3,PTN,MEG3,SH3GL3,NLGN1,ABLIM3,SLC22A4,SMARCD3,FAIM2,NFASC,ASTN2,ADGRL3,TIAM1,RUNDC3B,VSNL1,TRIM16L" Coexpression 19505326-SuppTable3 Human Ovarian_Li09_2322genes_cisplatinresistance GeneSigDB 7.26E-08 8.25E-04 8.09E-06 8.02E-05 272 1804 "ABHD6,AS3MT,ACTN1,GALNT13,ADD1,KIAA1211,RNF150,MTUS1,TBC1D14,SORCS2,AK2,ALCAM,SRPX,CEP126,PCDH10,ANK2,LCORL,PKP4,APC,TNRC6C,PPFIA3,LGR5,RASL11B,DYNLL1,CHID1,ADAM23,ADAM15,CFLAR,BMP7,SYNJ1,SGCE,C5,RAB29,DDR1,ZNF555,CALM1,CAPN3,CAST,NFS1,PRC1,CBFA2T2,SCARB1,SYNGR3,ARHGEF2,CDH2,LRRFIP1,CDO1,CLGN,CFL2,COPB2,B4GALT6,SLIT2,EPS15L1,RAB28,PLAA,PPT2,TPP1,CLTB,ARHGEF6,IQCK,ARMC8,SLC4A8,SMARCAL1,RTTN,CREM,AKAP12,HAPLN1,CS,ARHGEF10,ARHGAP24,HDAC4,TBC1D5,DBI,MYEF2,FBXL5,GSDME,SACS,FAM107B,CD99L2,NR1D2,CDON,ACOT8,PDCD6IP,ARRDC4,DNM1L,E2F5,EDNRA,PHC2,ANKRD46,CNNM1,PHF20L1,EGFR,TMEM35A,EIF1,EPB41,EPB41L2,CD320,SH3YL1,RACK1,ST3GAL6,CEP78,FDFT1,FGF13,FGFR1,FGFR3,FHL1,SEC23B,FOLH1,ZNF605,CSPG5,STAU2,MSANTD4,AP4B1,FYN,ZMAT1,KIAA1841,GATM,SESN1,COPS8,GLUL,HTATSF1,KCNMB4,LNX1,GPD2,TDRKH,FUT10,GPR37,GRB10,DIDO1,GSN,FAM107A,GUCY1A1,GUCY1B1,ZHX1,PACSIN2,MAN1B1,FRMD3,HMGCR,NEGR1,IDH3B,LRRCC1,LAMA2,LIFR,LMO2,NCOA7,LSS,PIK3AP1,MBNL1,MEF2C,MID1,MKLN1,MPP2,PTOV1,ZNF92,SAMD14,HS6ST3,NFE2L2,NFYA,CNOT4,NOVA1,OPA1,CLDN11,PCSK5,PDCD2,PDE4A,PDE4B,PDE4D,SLC10A4,PFKFB4,SERPINI1,PIK3R1,ZNF655,PKM,KCTD15,SMOX,PMP22,MAPKAP1,SCHIP1,ING3,LRRN3,PPP3CA,PKIA,MAPK10,PRPH,GDPD1,CNNM2,NDUFS7,VPS13C,PTX3,QDPR,ROGDI,TRIM68,MORC4,RFX2,RNH1,TMLHE,CARF,ROBO2,NEK11,RPL15,RTN1,SALL1,MAPK12,SEMA6D,LRFN5,SCN2B,SCP2,TNFRSF19,SEC14L1,ANKRD6,SLC6A8,SIRT2,CPEB4,EPC1,CXXC4,GKAP1,SMARCA4,RCOR3,TTC17,SNCA,LMBRD1,TMCC1,SPATA7,SP2,SPP1,PEG10,ZNF423,DBNDD2,ITPRID2,ELOVL4,KLHL7,ARHGEF9,VPS13A,DNAJC9,CAMTA1,ADGRL3,TCEA1,AP4E1,GPR161,SLC44A1,ARL10,TIAM1,HEY1,TK2,PARD3,TNS1,TPM1,TPM2,RGMB,PDSS1,STXBP4,TRPS1,TUBB2A,FLRT2,BCL2L13,RICTOR,ZNF74,ZNF138,POLR3H,FSTL5,MDH1B,MPPE1,PLSCR4,FZD3,UBE3B,PHTF2,RSPRY1,RNF170,ADAMTS10,NHSL1,IFT88,NETO2" Coexpression M19062 Genes up-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.64E-08 8.68E-04 8.42E-06 8.35E-05 272 1805 "ASIC1,ABHD6,NDRG2,KLHL32,PLEKHH1,ADORA1,SLC24A4,NME5,OSBPL6,CC2D2A,HFM1,CEP126,MARCH4,FGD2,C6orf89,CCDC146,SUGT1P4-STRA6LP-CCDC180,FAM131A,PHYHD1,BCAS1,STK33,NUMB,TTLL9,ZNF599,PROM1,BMPR1B,CASTOR3,CACNA1I,BAIAP3,CFAP410,CA12,CALM1,KALRN,CAMK2G,SLC25A14,CAST,CH25H,RUNX1T1,CLDN10,USP2,LRRFIP1,ZNF445,MAGI1,LRWD1,FOXN3,RPL32P3,NRXN3,HECTD1,CCDC151,FAM149A,ANKRD35,TOGARAM2,CDC42BPB,CRY2,GDA,CRYM,MROH8,SIPA1L1,DZIP3,PITPNM3,CTH,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,SCRN1,DNAL1,ELMSAN1,C2CD2L,KIAA0319,KLHL3,SPOCK3,FAM107B,KIF19,ZNF582-AS1,DNAH9,SLC12A6,ACOT8,PDCD6IP,TOM1,EBF1,SNX29,COPS4,RASGRP2,ERBB2,ANKMY1,EYA1,ABCA8,TUBB3,ZMYND10,FECH,FGF14,BAIAP2,AMOTL2,FHL1,SCARA3,IQCG,ATP13A4,FOLH1,EFCAB2,NBEA,TMEM107,TPPP3,SDCBP2,CHL1,GALC,TMEM8B,GATM,ALDH1L1,GPR162,USP19,GGT7,TOX3,GLUL,GNAL,GPT2,LNX1,PRUNE2,TPPP,DIDO1,SPACA9,SERP2,CACFD1,PTPRT,GSN,COQ10A,FAM107A,HLF,HMGCL,CFAP126,USP51,KNDC1,SCIN,KCNB1,KCNJ16,LMO2,SYTL4,PACRG,ZNF667-AS1,MAP6,MBP,CHST6,EFHB,MEF2C,MEIS1,MEIS2,AFDN,COL28A1,MSI1,MT1M,LAYN,NEXMIF,NBL1,IDNK,CCDC13,NF1,NFE2L2,PCBP3,NUCB2,OGG1,OXTR,PCDH9,PCSK5,ABCB1,DUSP26,ZFYVE21,PLXNB1,EPB41L4B,FA2H,VSTM2L,MAPK3,GRAMD1C,HYDIN,MASP1,DEF8,SNRK,QRICH1,WDR25,PTPRH,PTPRN2,PTPRO,TMEM231,ZNF844,CCDC40,FAM184A,ZCWPW1,BEND5,RFX2,RNH1,EXD2,RORB,MRAP2,SNX22,NEK11,ARMH4,BAALC,RPS6KA2,PLPPR3,HSD11B1L,ST6GALNAC6,TNFRSF19,SMPD3,KIF21A,FAM102A,SH3GL3,ARX,ASAP3,CPEB3,SYBU,ABLIM3,EPN2,SLC6A11,BTBD7,SLC22A4,ZNF667,INAVA,CABCOCO1,ANKFN1,PDZD2,SPATA7,TSNAXIP1,ATP10B,ARHGEF26-AS1,ADHFE1,COBL,MCF2L,PDLIM2,SYNE1,DOCK9,CCDC173,RNF175,SIK3,CYB561A3,DNAH7,DICER1-AS1,TMEM121,ZNF106,THRA,HEY1,TIMP4,TK2,ASXL3,LRRC8A,TNS1,CDK20,RUNDC3B,PPIL6,PRR18,TUBB2A,UBTF,GORASP1,ZNF709,CCDC136,CFAP298,PCDH20,ZBTB14,ZNF19,ZBTB38,REEP1,EML6,PROCA1,DNALI1,GDPD5,RNF103,TUBA1A,MDH1B,DNAH10,FAM182B,FBXO36,FAM219B,TTC7A,IFT88" Coexpression M2379 Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-30 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.81E-08 8.87E-04 8.53E-06 8.46E-05 34 116 "ACTN1,TAOK1,CALM1,CAST,LARGE1,CCPG1,CFL2,SOCS6,MAP4K4,ARHGEF6,CLOCK,MAML1,ELMO1,DDX46,DMD,CPEB2,DPYSL2,DTNA,LRRC17,TNRC6A,GNAO1,NOVA1,USP47,SEMA6D,SATB1,CHD9,FNDC3A,CPEB4,KDM3A,ADGRL3,SSBP2,TBC1D15,XPO1,PHTF2" Coexpression 15720813-TableS2b Human Brain_Hoelzinger05_117genes GeneSigDB 9.11E-08 1.04E-03 9.86E-06 9.77E-05 27 81 "PLEKHH1,KCNAB2,MADD,ARHGEF7,LDB2,CHN1,CNTN1,CRHBP,CRYM,FRY,RCAN2,GABRG2,HLF,MEF2C,TAGLN3,NELL2,NPTX1,ENPP2,SERPINI1,PRKCB,KLK6,PTPRN2,SMARCC2,SNCA,NEK4,R3HDM1,FIP1L1" Coexpression 15869706-TableS2 Human Cervical_Rosty05_814genes GeneSigDB 9.59E-08 1.09E-03 1.03E-05 1.02E-04 115 635 "AK2,BIN1,PPFIA4,APBA2,APC,GAS7,DDO,APOC1,APOC2,ZSCAN18,AZGP1,ADGRB3,BCHE,RGS9,BTK,CACNA1G,IL33,CAMK2A,CAMK2B,CH25H,CRLF1,CHN1,CHRNA4,B4GALT6,SLIT2,PCYT1B,AKAP6,COL9A3,CSF1R,VCAN,PPP1R16B,CYBB,ELMO1,EXOG,EGFR,PLXNC1,SRPK3,ELN,ETV1,NRN1,DLC1,FGFR1,FGFR3,FOXO3,FUT9,MPP6,FYB1,FYN,GABBR1,ALDH1L1,MSTN,HPGDS,GLUL,GNAO1,GPER1,GRIK4,GRM8,MUM1,HLF,HNMT,IGF1,ITGAM,LAMA2,LIG4,MEF2C,AFDN,N6AMT1,MYO7A,NEFH,NRCAM,PCDH9,PDE4B,ENPP2,PFKFB2,ABCB1,SNX10,PMP22,TRHDE,PRKCB,SAMD9,PTPRN2,RASGRF1,RGS4,RPS20,MAPK12,CSRNP3,FRMPD1,ANKRD6,SLA,SLC4A3,SLC6A8,SLC6A11,ZNF667,SMARCA4,OGDHL,ZSWIM8,NMNAT2,SAMSN1,SS18,SYT1,ADGRL3,TCF4,ZEB1,TRIM2,PCDHGC5,SYNE1,OBSL1,TRIO,TRO,KCNE5,LAT2,ZIC1,NDRG4,ZXDA,NAV3" Coexpression 15665281-Table2 Human Brain_Wong05_96genes GeneSigDB 9.95E-08 1.13E-03 1.06E-05 1.05E-04 24 67 "ALCAM,GAS7,CACNA1A,CBLN1,DCLK1,COL9A1,SUSD5,TSPAN5,CHL1,GABRG2,GNAO1,KCNK3,KCNN2,KIT,L1CAM,TAGLN3,NPTX1,PAX6,PPP3CA,RELN,PTPRE,SH3GL3,SYT1,FLRT2" Coexpression 20860821-TableS5 Human Pancreas_Rosero10_1018genes GeneSigDB 1.05E-07 1.20E-03 1.11E-05 1.10E-04 134 771 "NDRG3,NDRG2,ADORA1,USP35,AMPD3,FGD2,CPNE5,MADD,STK33,ZBTB10,ZNF583,SLC2A11,CFLAR,CALB2,HIP1R,RGN,ARHGEF1,ENTPD6,MAGI1,NUMBL,CLCN3,PCYT1B,SUMF2,COL11A2,RTTN,CDC42BPB,ANKRD44,AATK,BOC,GAPVD1,RASSF2,DBT,PITPNC1,SPATA2,DMPK,SLC12A6,SEZ6L2,FRY,OPTN,APH1A,MBNL2,PLEKHA1,EPB41,RASGRP2,PIPOX,OLFM1,FGFR1,SEC23B,KHDRBS3,GABBR1,ZNF274,SESN1,DHRS4,GRIN2C,GSN,COQ10A,BACH2,ACOT7,IDH3A,TJAP1,INSM1,ITGA7,GATD1,KIFC3,LAMP2,TAGLN3,MYO5A,CNOT4,PDCD2,ZDHHC8,SERPINI1,PIK3C2A,ZFYVE21,STRN3,PPP2R2B,MAPK9,SLC26A11,GDPD1,ZSCAN32,PTPRN,PTPRN2,RIPOR1,ROGDI,RDX,PRIMA1,SNX22,EPHA10,FBXW7,SPIN3,ZC3H14,GALNT10,MRAS,HSPA4L,SH3BP2,CHD9,CCDC92,FAM214B,ZNF430,SIRT2,GKAP1,SMARCA4,SNAP25,DBNDD2,IQSEC2,SSTR2,NXT2,SEPT8,SULF2,SYNE2,ARHGEF9,VPS13A,PLCB1,SYN2,PJA1,IQCE,DMXL2,DOCK9,SLC35G2,ZFPM2,THRA,TNS1,HIRA,UBTF,UCHL1,TOM1L2,ZNF23,ZNF24,POLR3H,DPYSL5,RNF103,MDH1B,WNK2,MARCH8,LAS1L" Coexpression M1105 Genes down-regulated in ME-A cells (breast cancer) undergoing apoptosis in response to doxorubicin [PubChem=31703]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.09E-07 1.24E-03 1.14E-05 1.13E-04 268 1781 "RALGAPA1,ACHE,CLK4,C3orf14,HACE1,OSBPL6,TAOK1,SPOP,BIN1,OGT,CDC42BPA,MAP4K3,PHF12,PKP4,APBB2,NT5C3B,CASK,ARRB2,NUMB,SLC4A4,ATP2A2,ATP6V0A1,RIPK1,BBS2,MPDZ,RGS11,BCS1L,NRP2,DST,ST3GAL5,FUBP1,MTMR3,MTMR2,CACNA1A,PTBP2,CAMK2G,CCNH,LRBA,DCLK1,LARGE1,ZNF445,MAGI1,TBRG4,SOCS6,RAB28,MYL6B,FAM19A5,QKI,HECTD1,CNN3,CNTN1,LETMD1,AHCTF1,RTTN,ZNF521,CLOCK,RBM39,AKAP12,NCOR1,ARHGEF10,PUM1,BOC,MYADM,DCAF8,EARS2,IP6K1,DBN1,ELMO1,RUSC2,GSDME,PARD6A,MED12,NR1D2,SLC12A6,TOM1,FARSB,DNM1L,TSPAN5,KLHL5,KMT5B,DCTN4,EPB41L2,GPHN,ERBB2,SPEG,PIPOX,RASL12,EZH1,ARMCX1,ACSL4,FKTN,STRADA,FDFT1,FECH,FER,POLR1B,FGFR1,MAD2L2,UBE2E3,FOXF2,VTI1B,SYNCRIP,NOP56,COQ5,TMEM175,EFCAB2,NBEA,ZBED3,USP21,TRIM16,TPK1,MPP6,FYN,NEURL4,GABBR1,GHDC,MTHFD2,INPP5K,TUBGCP4,SESN1,AHDC1,GHR,DHRS4,BRD8,TCERG1,DBF4,SPIN1,GLI2,TNRC6A,ZNF638,CBX1,HTATSF1,GNAO1,FERMT2,GPT2,ATE1,KAT7,ZBTB45,PSIP1,MAP4K5,RASSF8,DDX19B,HLF,ELOVL5,IGF1,IL6ST,KIF2A,TTYH2,LIMS1,LSS,MAP2,MAP6,MAPT,LYPLAL1,KITLG,PTOV1,MYO9A,SFR1,NF1,NFIX,NFYA,CNOT4,SMIM11A,OGG1,OLA1,PIK3C2A,PIK3R1,RETREG1,MAPKAP1,EXOSC10,SH3KBP1,DRAM2,PPP3CA,PPP3CC,KANSL1,PRKACB,CEP41,MAPK3,GDPD1,NDUFS7,QRICH1,CNTLN,PTCH1,PPP2R3C,USP47,RAP1GDS1,RDX,REV3L,ERI2,PBRM1,TMLHE,ELP2,PCMTD2,MCMBP,CLIP1,S100B,SEMA6D,ATXN2,ATXN7,SEC14L1,CASC3,SUPT20H,SCAF8,AMBRA1,SLC4A3,PPP4R3A,BTBD3,EPN2,CCDC88A,EPC1,ZKSCAN3,CDK5RAP2,IFT122,LIMCH1,LMBRD1,PDZRN3,KDM4B,ERC1,SPTAN1,RBM26,SPART,CLASP2,THSD1,ERBIN,NSFL1C,KLHL7,FBXW11,TBL1X,TCF4,ZFP90,TRIM2,TCF12,USP22,DOCK9,PUM2,TNS2,FRYL,TMEM121,ITGB3BP,SLC44A1,THRA,CBX5,ERCC6L2,TMPO,R3HDM1,PARD3,NR2C2,TRIO,PDSS1,TRPS1,HSPBP1,TTC3,UBE3A,USP1,LMF1,CLIP2,XPO1,XRCC4,ZBTB14,ZNF142,AMZ1,ZSCAN26,SMARCAD1,TUBA1A,VPS35L,PCBP4,SNX14,FRMD6" Coexpression 19567819-SuppTable1 Human Leukemia_Gross09_279genes GeneSigDB 1.15E-07 1.31E-03 1.19E-05 1.18E-04 58 257 "ACTN1,ADD2,PLEKHH1,SRPX,PCDH10,APOC1,RGS20,KIF1A,ST3GAL5,PRMT9,CA8,CALB1,CALB2,CALM1,ARHGEF6,MAGED1,PDE4DIP,KCTD8,DBN1,RCAN1,EIF5,GPHN,RACK1,UFM1,FYN,GAD1,MSTN,AP4S1,LINGO1,HBA1,AGBL5,INPP1,SYTL4,MATK,MEST,AFF1,GLIPR1L2,PMP22,RELN,RBBP6,HKR1,SPIN3,ST6GAL1,KBTBD4,TET1,DBNDD2,ZNF302,ARHGAP9,RNF175,HEY1,WBP2,UBC,SLC35A4,CCDC136,CLIP2,ZNF138,DNALI1,KCNAB1" Coexpression 17284527-TableS1 Human Lypmhoma_Leval07_644genes GeneSigDB 1.17E-07 1.32E-03 1.19E-05 1.18E-04 94 492 "KDM5D,XKR4,RNF157,ADD2,ESYT2,KIAA1324,OSBPL6,SRPX,CCDC74A,EIF4G3,ARHGEF7,CA8,CDO1,CHGB,CHN2,MS4A7,VCAN,FAM169A,PITPNC1,GSDME,FAM107B,CHRDL1,DMD,HS3ST2,FCF1,EPB41,RCAN2,EPHB1,ETV1,SIRPB1,NRN1,ACSL4,FCGR1A,FGF13,SCARA3,FYB1,SEPT9,LYVE1,HPGDS,GNG4,IRAK3,HAS2,FRMD3,BACH2,VSIG4,IGF1,IL6ST,JAK2,KCNN3,PIK3AP1,MATN2,MBNL1,MEST,PPM1L,MT1M,NELL2,NOVA1,NTRK2,PDE4B,PDE4D,ABCB1,PIK3C2A,CCSER2,RETREG1,PLCL1,PLIN1,PILRA,KANSL1,PTCH1,PTPN13,PTPRN2,MARCH1,RGS4,GLDN,LRRK2,S100B,SATB1,FNIP1,FAIM2,SPP1,KDM4C,PEG10,NFASC,TMEM150C,SATB2,PCDHAC2,GPRIN3,SIK3,UBE2H,UCHL1,P2RY12,ANKS1B,FZD3,JMJD1C" Coexpression M10276 "Genes down-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.24E-07 1.40E-03 1.25E-05 1.24E-04 34 118 "MTUS1,BEGAIN,LGR5,PROM1,BMP7,WASF1,PLEKHB1,SLIT2,LHX2,QKI,COL4A5,COL9A3,CNTNAP2,MFAP3L,CHRDL1,DMD,DTNA,EMX2,PDLIM5,FUT9,GATM,FAM107A,NACA,NELL2,GRAMD1C,TMEM255A,DGLUCY,HSPA4L,SOX3,SPART,SYNE2,ZMAT3,ZIC1,NAV3" Coexpression 15220918-TableS1a Human Viral_Wang04_1482genes GeneSigDB 1.24E-07 1.41E-03 1.25E-05 1.24E-04 189 1178 "ABHD6,ACTN1,ADD1,AP2A2,ADGRF5,SEMA6A,SPOP,BBOX1,BIN1,CDC42BPA,ARHGDIA,ARRB1,PLA2G4C,ASPA,ATP2B2,ATP6V0A1,KIF1A,AZGP1,ADGRB2,MPDZ,BID,ARHGEF7,FUBP1,SCAPER,RAB29,CA12,DDR1,THSD7A,CALM1,HIP1R,LDB2,CDC25B,DLGAP2,UBE2L6,TAOK2,TPP1,CLTB,CLTC,QKI,MAP4K4,RAB26,HOMER3,ARHGEF6,MAGED1,CREM,AKAP12,VCAN,CST3,DZIP3,PPP1R16B,DCAF4,RUBCN,DOCK4,ARHGAP32,ZFYVE16,SCRN1,IP6K1,DBN1,PITPNC1,ELMO1,B3GAT3,KLHL3,RHOBTB1,SV2B,DNAH9,DPYSL2,ACOT8,DTNA,EDNRA,EGFR,EIF5,MFSD10,EPB41L2,ANKMY1,RASL12,TUBA1B,DLC1,CHST15,FCGRT,OLFM1,CAMKK2,CELF1,FYN,DENND2A,GAD1,IQGAP2,ERAP1,MTHFD2,SEPT9,ALDH1L1,CYP46A1,NFU1,PCDH17,LYVE1,COPS8,FERMT2,GPD2,GPR37,GRB10,GUCY1A1,GUCY1B1,SYNPO,IFI16,IGF1,IL6ST,ITPKB,LMO2,LSAMP,SMAD1,SHC3,MEF2C,MEIS1,AFF1,ADAM22,MYCN,NF1,SLC11A2,OCRL,PAX6,SNX10,GPSM2,PCDHB17P,MASP1,CNNM2,GDPD2,PTK2,PTPRB,PTPRE,PTPRN2,RIPOR1,PPP2R3C,RAD17,RAP1GDS1,ZDHHC14,RGS3,RGS4,RNASE1,ZNF532,RPS6KA2,STK32B,EMID1,KCNIP1,CLIP1,RTN1,SEC14L1,GALNT10,HSPA4L,ASAP3,SHMT2,FNDC3A,CCDC92,ABLIM3,SLA,CCDC88A,SNCA,SOX15,GLT8D1,ZBTB43,ATP10B,MPRIP,STAU1,APOM,RGL1,TACC1,TAL1,MGRN1,TCF4,ZEB1,USP22,PCDHGC5,PHF24,TNS2,PCDHA2,TIAM1,HEY1,PARD3,TRIO,TSN,FLRT2,TBC1D15,VSNL1,WIPF1,CLIP2,REEP1,ANKS1B,GDPD5,TUBA1A,FAM182B,PHTF2" Coexpression M2571 Genes down-regulated during prostate cancer progression in the JOCK1 model due to inducible activation of FGFR1 [GeneID=2260] gene in prostate. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.28E-07 1.45E-03 1.28E-05 1.26E-04 66 308 "OGT,LGR5,PDE8B,SLC4A4,MYOM1,PROM1,CACNA2D1,CBS,P2RX6,CHN2,RAB26,ABI3BP,FAM171B,GREB1,HDAC9,SPOCK2,TMCC2,CHRDL1,DMPK,EYA1,MRVI1,NRN1,FHL1,KHDRBS3,CGREF1,FUT9,MTHFD2,SYT17,GGTA1P,GNAO1,GPT2,GSN,HLF,SCIN,CREG2,MAT2A,TM6SF1,N6AMT1,NPTX2,ENPP2,PIK3R1,PPP2R5E,PKIA,PTN,CEP97,RGS12,MEG3,HUNK,KCNIP1,SATB1,SH3BGR,FHOD3,LIMS2,LGI3,SMARCD3,SNRPN,TIMP4,BEX4,TPM1,TPM2,SYNPO2,RBFOX3,CLDND1,REEP1,PCBP4,ST8SIA2" Coexpression 18713946-TableS3 Human Lymphoma_Sander08_1021genes GeneSigDB 1.35E-07 1.54E-03 1.34E-05 1.33E-04 109 597 "MTUS1,AMPD3,APBB2,ZBTB10,NCOA1,NUMB,STX16,SLC2A11,RIPK1,BID,BLM,CFLAR,ARHGEF7,CACNA1A,PTBP2,CBS,ARHGEF2,CLGN,CHN2,MS4A7,RAB33A,LY86,PDE4DIP,CTH,ARHGAP24,SACS,DPYSL2,MBNL2,KMT5B,PLXNC1,VPS13B,FER,PCYOX1,EVL,TMEM107,PDLIM5,OGA,ZMAT1,ACSS1,KIAA1841,SESN1,GLUL,ZNF638,ZNF782,EID2B,LRRCC1,IL6ST,LYPLAL1,MEF2C,MIA2,MKLN1,AFF1,MPP2,N6AMT1,NINJ2,CNOT4,OXTR,ZNF655,PSAT1,ING3,PILRA,PRKACB,CEP41,SLC26A11,SAMD9,VPS13C,PTPRE,OXR1,ZNF532,SETD5,RPS6KA2,KCNIP3,MRAS,CHD9,R3HDM2,WDR37,FAM81A,ATF7IP,CPEB4,GKAP1,TTC17,SNRPN,FNBP1,PBLD,DNAJC9,TCF12,FRYL,ITGB3BP,ZMAT3,TLR4,TMPO,NPL,ZNF346,TRIO,TTC3,UBE2H,USP1,TBC1D15,RICTOR,KCNK12,XRCC4,ZNF711,SLC38A1,PLD4,JMJD1C,RSPRY1,TTC7A,ZDHHC20,SENP7" Coexpression M6782 Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.42E-07 1.62E-03 1.39E-05 1.38E-04 139 811 "CLK4,BRAP,MTUS1,AMPD3,MAP4K3,NCOA1,NUMB,N4BP2L1,BACH1,DST,ARHGEF7,MTMR3,RAB29,PTBP2,SPAG9,CBFA2T2,SYNGR3,ARHGEF2,NPIPA1,SRSF11,FAM189A2,RBM39,HINFP,PDE4DIP,FAM169A,CTH,PUM1,IST1,IP6K1,ARMCX2,NR1D2,DMTF1,RCAN1,DNAJB6,ABCC5,HIPK3,FEM1B,OPTN,FAM13A,MBNL2,EIF5,RGS17,DCTN4,USPL1,EIF1,CDKL3,EZH1,RPS6KC1,ST3GAL6,SEC24B,FGFR1,IP6K2,TRMO,UFM1,TRIM16,CELF1,OGA,ZNF274,MTHFD2,RAB40B,PRRC2B,GRB10,BTN2A1,FICD,MAP4K5,MUM1,HSF2,IFI16,TJAP1,IL6R,KPNA5,LSS,MARK3,MBP,KITLG,MKLN1,MXI1,MYO9A,NCF2,NFE2L2,NFYA,CNOT4,PFKFB3,CCSER2,PKD1,PLCD1,SMOX,ZNF426,PMP22,RETREG2,FA2H,MAPK7,RELN,PTX3,RIPOR1,SLC25A36,DCUN1D2,SETD5,AP1AR,HSPA4L,FAM102A,WDR47,SLC6A8,ATF7IP,TTC17,TMCC1,KDM4B,PDZD2,KDM3A,SP2,CDK19,ZBTB43,TSPYL2,CAMTA2,LARP4,TTBK2,RGL1,STX1A,JMJD6,ANKRD12,TAF9,SIK3,SIRT1,GPR161,HEY1,TP53BP2,NR2C2,TSC1,ZKSCAN5,TUBB2A,UBE2H,TBC1D15,CLIP2,WRN,ZNF24,PRDM10,RNF103,JMJD1C,FXR1" Coexpression M687 Genes up-regulated in neurons after NPAS4 [GeneID=266743] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-07 1.63E-03 1.39E-05 1.38E-04 42 163 "ABCF1,C3orf14,ADD2,ARHGAP20,LRFN1,RNF182,ARHGEF7,PLCXD3,SPOCK2,KIAA0319,MTX3,FAM107B,RCAN1,C8orf37,VPS26C,DNAJC27,ATP2C1,TMEM8B,PCDH17,ACOT7,STXBP5,MSI1,ALDH1L2,NTRK3,PFKFB4,PRKAB2,PKIA,RASGRF2,RBBP6,TSPY26P,MRAS,SGK1,ST6GAL1,FAM81A,SLC8A1,TRIM67,RBM34,AP4E1,SMUG1,MKRN3,LYPD6,MARCH8" Coexpression M6100 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.52E-07 1.73E-03 1.47E-05 1.45E-04 58 259 "ELFN2,GALNT16,PLEKHH1,ZNF608,EPB41L5,APLP1,ADGRB2,MYRF,LDLRAD4,VXN,LRRFIP1,MAGED1,CRMP1,HAPLN1,TCAF1,JAKMIP2,TIAM2,LYPD1,EBF1,EDIL3,EDN1,RASA4,AASS,MTSS1L,FDFT1,FGFR1,BAIAP2,EFCAB2,SYT17,CSDC2,GLI2,TOX3,GSN,HMGCR,ITGA7,L1CAM,LSS,MATN3,MEIS1,GPR137C,ZNF827,PDE1C,CYTL1,CCSER2,PTPRN,SCN2B,COPZ1,ARHGEF40,TCF4,TRIM2,PCDHB10,OBSL1,TK2,CBX5,TNS1,TRO,VGF,TUBA1A" Coexpression 17760805-SuppTableS2a Human Leukemia_Boag07_100genes_pre-BALLvCD34_UP GeneSigDB 1.57E-07 1.78E-03 1.50E-05 1.49E-04 26 78 "SEMA6A,LGR5,PDE8B,CALM1,LARGE1,RCBTB2,MYRIP,ARHGEF10,ARHGEF4,MAMLD1,FGFR1,TRAF3IP2,LILRA2,PCLO,PPP3CC,PTK2,MORC4,ZSWIM8,ZNF423,RGL1,SIN3B,PCDHGC5,PARD3,CLIP2,KCNK12,TFIP11" Coexpression M14791 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.66E-07 1.89E-03 1.58E-05 1.56E-04 63 291 "XKR4,TMCC3,PCDH19,DPP10,ANK2,ASPA,SLC4A4,BCHE,CA4,USP2,CHGB,ABCG2,ABI3BP,AKAP12,HAPLN1,SV2B,CHRDL1,EDIL3,EDN3,ENPP6,TLR7,ABCA8,C2orf88,GCNT2,GHR,LYVE1,FAM107A,IGF1,IL6R,INSM1,L1CAM,LIFR,ZNF667-AS1,MEIS1,MT1M,NEXMIF,NPY,PCDH9,TMOD2,CYTL1,FXYD1,PRKCB,CNNM2,LAMA1,GDPD2,PTN,TMEM255A,BEND5,PRIMA1,GLDN,LRRK2,RTN1,SEMA6D,SCN7A,SLC22A4,MIR100HG,SST,WSCD1,TNS1,SYNPO2,RUNDC3B,FLRT2,FAM13C" Coexpression M5591 Genes up-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-07 1.95E-03 1.61E-05 1.60E-04 48 199 "BIN1,N4BP2L1,BID,CALM1,CAST,RHBDL1,USP6,DCLK1,CLOCK,PUM1,GPRASP1,ZNF337,EGFR,IRAK4,PCOLCE2,EIF1,EZH1,FAM198B,SESN1,GFRA2,MALT1,DIDO1,BTN2A1,HSF2,IL6ST,MBP,MYH3,NACA,NPR2,PDE4B,MTRF1L,SDK2,PTX3,C1orf54,CCDC102B,MCMBP,RXRA,SLC14A1,INAVA,PLCB1,KAT6B,UGT8,WNT7A,ZNF142,ZNF184,VPS35L,HNRNPA3,JMJD1C" Coexpression 19286929-SuppTable1 Mouse Lung_Rangasamy09_2003genes GeneSigDB 1.90E-07 2.16E-03 1.77E-05 1.76E-04 246 1621 "ABCF1,ACTN1,FMNL2,CCDC85A,TMCC3,ADD1,BRAP,ADRB2,AP2A2,MTUS1,OSBPL6,SORCS2,TAOK1,ALCAM,LTBP4,PITPNM2,AMPD3,CDC42BPA,SEMA7A,PKP4,SHROOM2,PRX,ARNTL,CDK13,ATP1A1,ATP2B2,ATP6V0A1,MYOM1,BACH1,NRP2,GPR146,DST,DDR1,PTBP2,CBR1,USP2,SCARB1,CD38,ARHGEF2,SEPT7,MAGI1,CCPG1,SOCS6,TPP1,CLTB,FAM189A2,ABCG2,HECTD1,COL4A5,ABI3BP,MYRIP,CLOCK,CDC42BPB,C2CD2,CRY2,GDA,ABCG1,LRIG1,CSNK1E,CSNK1G3,PUM1,USP6NL,GPRASP1,LONRF1,MATR3,DAPK1,SPOCK2,DBT,SPATA2,ELMO1,RUSC2,DDX46,FAM107B,USP3,NR1D2,CPEB2,SLC12A6,PDCD6IP,RCAN1,ARRDC4,DTNA,EDN1,EDNRB,PHC2,HIPK3,FEM1B,KLHL5,TMTC1,FRY,FAM13A,EGFR,EIF5,ELN,EIF1,HSPA12B,ACSL4,ST3GAL6,CHST15,SEC24B,FGF1,FGF13,FGFR3,BAIAP2,FHL1,IP6K2,PCYOX1,SYNCRIP,FLT1,UFM1,PDLIM5,TRIM16,OGA,SDCBP2,GAA,GALNT15,B4GALNT1,MTHFD2,IGSF5,GCNT2,SESN1,PCDH17,MALT1,LYVE1,DBF4,GLUL,GNAO1,GPT2,PRRC2B,LILRB4,STON1,STMN2,FAM107A,GUCY1A1,GUCY1B1,VSIG4,HMGCL,NKD1,IL6ST,ITPKB,KIT,SMAD1,GPR155,MAPT,MBD1,KCTD6,MKLN1,AFF1,PTOV1,MXI1,MYO5A,NFE2L2,NPTX1,P2RX7,PDE4B,PFKFB3,FAM98B,PGAM2,PIK3R1,SNX10,ZFYVE21,RETREG1,PLEC,SMOX,PLTP,STRN3,LRP12,PSAT1,PPM1B,PPP2R5E,RASGEF1B,PRKAR1B,GDPD1,PSMA6,SNRK,QRICH1,ANKHD1,PTPRB,PTX3,USP47,CCDC40,RBBP6,ZDHHC14,RDX,RGS12,RIC8B,TMLHE,ELP2,RPS20,TRA2B,HSPA4L,SGK1,EPN2,LIMS2,SEPHS1,SIRT2,SLC12A2,LGI3,EPC1,ZFP1,CDK5RAP2,SNCA,MBD5,PDZRN3,DOP1A,PDZD2,KDM3A,ZHX3,SP2,TSPYL2,SPART,LARP4,ERBIN,JMJD6,SYNE2,MCF2L,TAF9,DNMBP,ADGRL3,TBCEL,ATMIN,TCF12,CLASP1,DOCK9,ARHGAP9,DICER1,CHST8,BEX4,PARD3,TNS1,WBP2,TSC2,ZKSCAN5,UBC,RPL7L1,EIF4ENIF1,UBE2H,SLC35A4,TBC1D15,TSPAN11,RICTOR,ZFAND5,MAP3K12,ADAMTS9,SEMA3B,FIP1L1,RNF146" Coexpression M2494 Genes down-regulated in primary LEC cells (lymphatic endothelum) upon overexpression of MIR31 [GeneID=407035]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.92E-07 2.18E-03 1.77E-05 1.76E-04 82 416 "OSBPL6,TRMT9B,RGS20,PLA2G4C,N4BP2L1,MYOM1,LDLRAD4,CA4,LDB2,CLGN,SOCS6,PLEKHB1,ABCG2,ANKRD35,CREM,AKAP12,KIAA0040,RASSF2,SPOCK2,AIF1L,SV2B,EBF1,EDNRB,DCTN4,VPS13B,HSPA12B,GTF2IRD2,FGF12,ZMAT1,DISC1,CYP46A1,LYVE1,KCNMB4,PCLO,STMN2,BVES,GUCY1A1,RBPJ,ZNF678,LAMA2,SMAD1,AFDN,MMP16,MX1,NCF2,IDNK,NRCAM,P2RX7,PPARA,SAMD9,SH3TC2,RASGRF2,RNASE1,ZNF532,GSTCD,ROBO1,SPIN3,KCNIP1,ZNF568,STUM,KIF21A,CHD9,SLC4A3,ZNF667,FAIM2,ZNF415,PDZD2,MYCBP2,SPP1,PEG10,KANK1,PLCB1,TACC1,ADGRL3,PCDHGC5,HEY1,IL34,FLRT2,ZNF177,ADAMTS9,ZDHHC20,SENP7" Coexpression M4305 Genes up-regulated in comparison of naive vs effector CD8 T cells (3.5 days postinfection). MSigDB C7: Immunologic Signatures (v6.0) 2.01E-07 2.29E-03 1.82E-05 1.80E-04 48 200 "ADCY5,ADD2,KIAA1211,PTCHD1,SPARCL1,PTCH2,CPNE6,SLC35F1,CSF1R,AIF1L,SV2B,SLC29A4,DRP2,FAM78B,SRPK3,SCML2,CORO2B,FUT9,TMEM8B,GPR162,CSDC2,GPR12,CCDC184,PCLO,KCND2,NBL1,NPY,PLCL1,PNMA3,VSTM2L,EPDR1,PTPRN,TMEM200C,SH3GL3,SLC2A5,EPN2,SLC8A1,ARHGEF40,RHBDL3,SYN1,SYP,PCDHB7,ZFPM2,PARD3,TTC3,FSTL5,ADAMTS9,IFT88" Coexpression M7553 Genes up-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.01E-07 2.29E-03 1.82E-05 1.80E-04 48 200 "GPRASP2,APC,VAT1L,CADPS,MPDZ,SOCS6,AKAP6,CREM,MYADM,GSDME,RAB39B,DNAJB6,FSD1L,OPTN,LINC00654,SYT17,FREM1,SPIN1,IFI16,KIF5A,NCOA7,LSAMP,TAGLN3,ABCB1,PIK3R1,LRRN3,PRKACB,GDPD1,PTPRH,TUG1,ZNF793,EXD2,CLIP1,RTN1,WDR47,NAPB,CLASP2,SSTR2,SYT1,PCDHB10,BEX4,ZNF711,ZNF540,REEP1,ZNF177,LOC100506497,AMN1,CASC15" Coexpression M9203 Genes up-regulated in CD8 T cells: naïve versus day 8 after LCMV infection. MSigDB C7: Immunologic Signatures (v6.0) 2.01E-07 2.29E-03 1.82E-05 1.80E-04 48 200 "AS3MT,ADCY6,TMCC3,ZNF608,WDR35,GPRASP2,NT5C3B,ZFYVE28,ALDH7A1,BCL7A,PTBP2,ARHGEF6,COL4A5,CSNK1E,GREB1,DAPK1,RASGRP1,ENO2,ARMCX1,PRMT5,BAIAP2,TMEM164,UBE2E3,STAU2,CHL1,TDRKH,MAP4K5,BACH2,ZDHHC15,CELF5,IL6ST,SMAD1,ADAM11,AFDN,PRKCB,MAPK7,BEND5,GTDC1,SATB1,ST6GAL1,DZIP1,TET1,ZC4H2,BHLHB9,TTC3,TUBB2A,XPO1,SLC30A4" Coexpression 18381933-SuppTableS4 Human Breast_Vincent-Salomon08_1001genes GeneSigDB 2.25E-07 2.55E-03 2.01E-05 1.99E-04 134 781 "RALGAPA1,ADCY6,BRAP,OSBPL1A,KIAA1324,AMT,PKP4,APBB2,FAM131A,MADD,MARK4,CHRD,ATP1B3,STX16,N4BP2L1,ADAM15,BMPR1B,CA12,SLC16A4,SCARB1,LRBA,ARHGAP33,MAGI1,CACNA2D2,SRSF11,CHN1,PLEKHB1,MYL6B,MAP4K4,WHRN,LETMD1,SH2B1,NCOR2,ABCG1,SOCS5,CST3,KIAA0040,GREB1,PPP6R2,DCAF8,DAPK1,ARMCX2,FBXL5,NR1D2,DOCK2,FEM1B,FRY,RASA4,KCTD3,COPS4,TNK2,DCTN4,GPHN,ERBB2,ERBB4,EZH1,F8,ARMCX1,FCGRT,FGFR1,SYNCRIP,EVL,PDLIM5,ZNF44,SYT17,BRD8,GLYR1,MSL3,GLUL,PADI2,HMGCL,AGFG1,IRF8,IL6ST,LIMS1,MAN2A2,MAPT,MATN2,PTOV1,NF1,NOVA1,NTRK2,NUCB2,OXTR,SERPINI1,MAPKAP1,RETREG2,FA2H,MINDY2,ELOVL2,PTN,PTPN13,SUSD4,RBBP8,RET,ROBO1,PCMTD2,ZC3H14,STK32B,AP1AR,SH3BGR,SYBU,CDK5RAP3,SMARCA4,SMARCC2,SMARCD3,INTS9,LMBRD1,KDM4B,SOX11,GLT8D1,DBNDD2,SPTAN1,CLSTN2,POGZ,KANK1,ANKRD28,MLST8,DNMBP,TBL1X,SIK3,ZNF106,TRPS1,SGK3,UBE3A,LMF1,WRN,UPF3A,MAP3K12,DNALI1,SEMA3B,NAV3,FZD3,FXR1" Coexpression M2019 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.28E-07 2.59E-03 2.01E-05 1.99E-04 107 589 "KCNH8,ACHE,EMILIN3,ELFN2,UNC5A,MARCH4,ALK,DOC2A,DPP10,APBA2,ATP1A3,ATP2B2,ADGRB1,ADGRB3,CA4,CALB1,CALB2,CABP7,CAMK2B,DLGAP2,CACNA2D2,CHGB,CHRNA4,MYRIP,CRHBP,C1QL2,CRYM,AATK,LRRC3B,PHACTR3,RASGEF1C,PPP1R16B,ZNF804A,TMEM130,HS3ST2,CNNM1,RASGRP2,FGF11,FGF12,FGF14,PSD2,CSPG5,DLL3,GAD1,SRRM4,CPLX2,CPLX1,RUNDC3A,AIFM3,LUZP2,GP1BB,GPR12,GRIA2,GRIN2C,PTPRT,GSTT2,PADI2,IGFBPL1,SHISA6,SOWAHA,KNDC1,INSM1,CDH20,KCNB1,KCNQ3,ADAM11,NTRK3,OXTR,PCDH8,NECAB2,PPP2R2C,VSTM2L,SKOR1,RELN,PSD,PTPRN2,IQSEC3,CRTAC1,ZMAT4,LGI2,SGSM1,STK32B,KCNIP1,LRFN5,SCN8A,SLC6A11,MAST1,SNAP25,SST,TMEM150C,TACR1,MCF2L,TAL1,WSCD1,PHF24,NR2E1,PRRT1,CSMD1,UGT8,MGAT5B,RBFOX3,WNT7A,CELF4,LAMP5,PRDM8,NETO1,JPH3" Coexpression 18172295-SuppTable3 Human Bone_Heller08_470genes GeneSigDB 2.28E-07 2.59E-03 2.01E-05 1.99E-04 78 391 "ALCAM,BIN1,APLP1,CDC14B,CACNA1G,WASF1,BAIAP3,CALM1,SPAG9,CCK,SLC16A4,LHX2,SLC4A8,AKAP12,CNTNAP2,DZIP3,CTH,DBN1,ARMCX2,AASS,TENM1,RASGRP2,CDKL3,TUBB3,TAOK3,FER,FGFR1,FGFR3,BAIAP2,FHL1,PDLIM5,CGREF1,CSPG5,GLUL,PCLO,GSN,HBA1,ITGA7,KCNN2,KHK,L1CAM,LIFR,MAPT,MEF2C,MYCN,NFYA,NPTX2,PCDH9,ENPP2,PFKFB3,ABCB1,SERPINI1,GPSM2,PRPH,PTK2,NUDT11,RPS6KA2,RPS20,SCP2,SMPD3,SH3BGR,SH3GL3,PPM1E,DZIP1,ANKRD6,SLC6A8,OGDHL,SMARCD3,SNAP25,ZSWIM8,SPP1,PEG10,SYN1,SYT1,CAMTA1,TPM1,TST,SLC17A7" Coexpression M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.38E-07 2.70E-03 2.08E-05 2.06E-04 57 256 "BIN1,SHROOM2,MARCH3,DGKI,CDH2,LOC730101,FOXN3,CHN1,ARHGAP22,MAGED1,NECTIN3,LRIG1,VCAN,SLITRK5,DOCK4,ARMCX2,RHOBTB1,RGS17,PCOLCE2,ENO2,RCAN2,ABCA8,DLC1,FGFR1,FERMT2,PRUNE2,GRB10,RNFT2,HAS2,ITGA7,MITF,NPTX2,PCDH9,ENPP2,PMP22,PTX3,PID1,FAT4,ENOX1,RGS4,ZFHX4,RPS6KA2,GALNT10,CCDC92,ABLIM3,ARHGEF40,SLC22A4,CDK5RAP2,RGL1,TBL1X,SATB2,ZEB1,SYNE1,BEX4,TPM1,WIPF1,ATP6V0E2" Coexpression 17952126-SuppTable1 Human Bladder_Buytaert08_832genes GeneSigDB 2.47E-07 2.80E-03 2.14E-05 2.12E-04 137 804 "CLK4,BRAP,MTUS1,AMPD3,MAP4K3,NCOA1,NUMB,N4BP2L1,BACH1,DST,ARHGEF7,MTMR3,RAB29,PTBP2,SPAG9,CBFA2T2,SYNGR3,ARHGEF2,SRSF11,FAM189A2,RBM39,HINFP,PDE4DIP,FAM169A,CTH,PUM1,IST1,IP6K1,ARMCX2,NR1D2,DMTF1,RCAN1,DNAJB6,ABCC5,HIPK3,FEM1B,OPTN,FAM13A,MBNL2,EIF5,RGS17,DCTN4,USPL1,EIF1,CDKL3,EZH1,RPS6KC1,ST3GAL6,SEC24B,FGFR1,IP6K2,FOXO3,UFM1,CELF1,OGA,ZNF274,MTHFD2,RAB40B,PRRC2B,GRB10,BTN2A1,FICD,MAP4K5,MUM1,HSF2,IFI16,TJAP1,IL6R,KPNA5,LSS,MARK3,MBP,KITLG,MKLN1,MXI1,MYO9A,NCF2,NFE2L2,NFYA,CNOT4,PFKFB3,CCSER2,PKD1,PLCD1,SMOX,ZNF426,PMP22,RETREG2,FA2H,MAPK7,RELN,PTX3,RIPOR1,SLC25A36,DCUN1D2,SETD5,AP1AR,HSPA4L,FAM102A,WDR47,ATF7IP,TTC17,TMCC1,KDM4B,PDZD2,KDM3A,SP2,CDK19,ZBTB43,TSPYL2,CAMTA2,LARP4,TTBK2,RGL1,STX1A,JMJD6,ANKRD12,TAF9,SIK3,SIRT1,GPR161,HEY1,TP53BP2,NR2C2,TSC1,ZKSCAN5,TUBB2A,UBE2H,TBC1D15,CLIP2,WRN,ZNF24,PRDM10,RNF103,TRIM16L,JMJD1C,FXR1" Coexpression M6746 Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.56E-07 2.91E-03 2.19E-05 2.17E-04 43 172 "MTUS1,C1QTNF1,CDC42BPA,GAS7,PHYHD1,RIPK1,ADAM15,GPR146,DST,PRMT9,SGCE,TPP1,CLTC,LY86,PLXNA4,TM9SF4,FBXL5,RASGRP1,CALCRL,ETV1,FOLR2,GALC,LYVE1,HPGDS,GPR75,TPPP,IRAK3,VSIG4,IGF1,LRRC25,TTYH2,LIFR,NCF2,OCRL,P2RX7,DRAM2,PTPRB,SLC11A1,DMXL2,TMEM9,LRRC8A,NPL,P2RY12" Coexpression M12892 Genes up-regulated in the luminal B subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.56E-07 2.91E-03 2.19E-05 2.17E-04 43 172 "BMPR1B,BAIAP3,LDLRAD4,CA12,CAMK2B,RHBDL1,CACNA2D2,CHN2,RAB26,GREB1,CELSR3,KCTD3,ERBB4,ZMYND10,EVL,TPPP3,SYT17,GPR162,TOX3,PCLO,GRIA2,PTPRT,IL6ST,INSM1,MAPT,MYT1,NELL2,NOVA1,SERPINI1,RETREG1,NKAIN1,QDPR,RET,STK32B,SYBU,IFT122,KDM4B,CLSTN2,SSTR2,SYT1,TRIM9,DNALI1,SEMA3B" Coexpression M13273 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.64E-07 2.99E-03 2.23E-05 2.22E-04 53 232 "SRPX,ASGR1,SLC4A4,ALDH7A1,PROM1,CA4,LDB2,COL9A3,AKAP12,IPCEF1,CTH,ELMO1,CHRDL1,DPP6,EDN3,SEMA3D,RGS17,NRN1,FGF13,FHL1,IQGAP2,GFRA2,GHR,GPER1,PCLO,HBA1,HLF,KIT,LAMA2,LIFR,LMO2,MATN2,LRP1B,MEIS2,MYCN,ZNF862,NUCB2,FXYD1,EPB41L4B,PRKACB,RELN,PTN,SH3BGR,SLC14A1,ZNF302,TAL1,SYNE1,TEK,ZFPM2,FLRT2,NDRG4,SLC38A1,KCNAB1" Coexpression M6315 Cluster 2: genes down-regulated in lung tissue samples from mice with oncogenic form of KRAS [GeneID=3845] and inactivated PTEN [GeneID=5728]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.71E-07 3.08E-03 2.28E-05 2.27E-04 72 353 "ADCY8,GALNT13,SPARCL1,ABCD2,MPDZ,CACNA1A,LDB2,METTL6,ARHGEF2,DCLK1,NDST3,TMEM184B,AKAP12,PDE4DIP,ARHGEF4,EARS2,TMEM170A,ELMSAN1,SV2B,CDON,EBF1,TMTC1,EIF4G2,CALCRL,RASGRP2,NCALD,FGF14,FHL1,FOXF2,ATP13A4,ST6GALNAC3,GPD2,GSN,MAN1B1,SHISA6,IRF8,MAP2,MAP4,MEIS2,KITLG,MYO5A,MYT1,ENPP2,PFKFB3,ABCB1,PLTP,PMP22,FA2H,IRX1,PTPRD,NKAIN1,SUSD4,ZMAT4,ZFHX4,CLIP1,SATB1,EPN2,INTS9,PDZD2,ZSWIM8,DDN,SPART,SYN2,FBXW11,TEK,ITGB3BP,TPM1,RGMB,CLEC2L,RICTOR,ZBTB14,AMZ1" Coexpression M13061 Genes selected in supervised analyses to discriminate cells expressing E2F3 [GeneID=1871] from control cells expressing GFP. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.90E-07 3.29E-03 2.42E-05 2.40E-04 55 245 "HACE1,ADGRB2,DIS3L,B4GALT6,ABCG2,RAB26,LRIG1,TSPAN5,PCOLCE2,USPL1,ENO2,CEP78,FGFR3,CAMKK2,KHDRBS3,CSPG5,NSG1,KDM2B,GNAL,TPPP,PSIP1,FAM222A,UBE2QL1,SLC35G1,METTL21A,TM6SF1,KCTD6,TMOD2,PFKFB3,RETREG1,KCTD15,EPB41L4B,PTCH1,NCR3LG1,SCN8A,MRAS,SH3BGR,FERMT1,GKAP1,KDM4B,PEG10,CDK19,STXBP1,DNAJC9,SIN3B,TIAM1,HEY1,UGT8,LYPD6,REEP1,EML6,ZNF195,SLC30A4,PHTF2,NETO2" Coexpression 19074828-TableS4 Human Leukemia_Agirre08_1149genes GeneSigDB 2.91E-07 3.31E-03 2.42E-05 2.40E-04 127 734 "SYN3,ACHE,ADCY8,BRAP,OSBPL1A,DOC2A,CDC42BPA,APBB2,BCAS1,SEMA4G,MADD,ARHGDIG,PDE8B,BCHE,CFLAR,ARHGEF7,FUBP1,CA4,SLC25A14,CCK,MTMR7,CD86,ARHGEF2,NDST3,QKI,HOMER3,COL4A5,TBPL1,NCOR1,SNCAIP,OSBPL3,DZIP3,CTH,GREB1,ARHGEF4,KIAA0408,HDAC4,TM9SF4,TBC1D5,DAPK3,BRINP1,TIAM2,DNM1,DMPK,EDIL3,EDNRB,KLHL5,CELSR3,AASS,EIF4G2,IRAK4,ANKMY1,ZMYND10,FER,FGF12,POMT1,DISC1,GRIA2,GSTM5,AP4S1,INPP5B,KCNQ3,PACRG,PTOV1,MYT1,FXYD7,NFIX,NOVA1,NTRK2,NTRK3,OCRL,PCDHGC3,PDE4A,PFKFB4,ABCB1,PIK3R1,PKD1,MTRF1L,MAPKAP1,PPP3CC,MASP1,BCAS3,PTN,PTPRD,RAP1GDS1,RBBP6,GAL3ST4,RGS12,S100B,DZIP1,SLC12A2,ATF7IP,SMARCA4,SNAP25,KIF13A,SNRPN,FNBP1,UNC5B,ZNF423,SPTAN1,SPTB,ARHGEF9,PLCB1,TACR1,TAF6,TCF4,SATB2,PUM2,PCDHA5,SLC35G2,ACTR6,SMUG1,TRIO,AMACR,TSC2,UBE3A,USP1,VIPR2,ZNF23,TRIM9,ZNF45,SPHK2,EVI5,RNF103,ADAMTS9,SEMA3B,SENP7" Coexpression 18855877-TableS2 Human Sarcoma_Filion09_404genes GeneSigDB 3.00E-07 3.41E-03 2.46E-05 2.44E-04 64 302 "NDRG2,C1QTNF3,ARHGDIG,ZBTB10,ADGRB3,SYNJ1,MTMR3,RGN,DLGAP1,NDST3,CLCN3,MAP4K4,ABI3BP,MYRIP,NECTIN3,CLOCK,HAPLN1,CSF1,VCAN,RIMS2,ZNF337,TBC1D5,SPOCK3,RCAN1,DTNA,EDIL3,SEMA3D,MBNL2,PCOLCE2,RCAN2,ETV1,CORO2B,ST3GAL6,FGF12,FGF14,FHL1,GNAO1,GPR12,KCNJ16,MBNL1,LRP1B,MMP16,PGAM2,PDZRN4,PRKACB,RELN,MARCH1,PID1,RET,KLHDC8A,SH3GL3,SYBU,BTBD3,SLC14A1,SNCA,USP33,ATP10B,SLC19A3,SLC44A1,TLR4,TRIM9,ADAMTS9,RTN4,NETO2" Coexpression 18308945-Table3 Human StemCell_Huang08_60genes_NSCs GeneSigDB 3.01E-07 3.42E-03 2.46E-05 2.44E-04 20 52 "SPARCL1,ANK2,DCLK1,LRRC3B,EDNRB,ETV1,CSPG5,MEGF10,GAD1,GRIA2,FAM107A,MAP2,PAX6,SLC10A4,PTN,SALL1,SEMA6D,ARX,SOX11,ZIC1" Coexpression M10961 Genes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [GeneID=2099]) compared to the parental MCF7 cells which do. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.13E-07 3.55E-03 2.54E-05 2.52E-04 132 771 "NCKAP5,KIAA1324,ALCAM,PCDH10,APBB2,EPB41L5,BCAS1,SHROOM2,CASK,ZNF583,MPDZ,BMPR1B,RAB29,CA12,CACNB4,DCLK1,LARGE1,CCPG1,PLEKHB1,SLIT2,EPS15L1,FAM189A2,COL4A5,ANKRD35,AKAP5,MAGED1,NSL1,FAM169A,GREB1,CCDC144A,HDAC9,SCRN1,ARMCX2,YTHDC1,LYPD1,SGSM2,CPEB2,SLC12A6,DTNA,EDN1,RASGRP1,TMTC1,EGR3,ERBB4,FAM198B,CHST15,OLFM1,FGF13,EVL,NBEA,PDLIM5,TPK1,FUT9,GAD1,RAB40B,GPER1,GPR37,ATP2B1-AS1,GSN,GUCY1B1,UBE2QL1,ZDHHC15,LRRCC1,KLHL23,MAP2,MATN3,KITLG,PPM1L,MITF,MMP16,MX1,MYO5A,MYO6,NCAM2,NELL2,CNOT4,NRCAM,NUCB2,GPR137C,KCTD15,SDK2,PKIA,DIRAS2,MASP1,SAMD9,PTPN13,PTPRG,SUSD4,RBBP6,RET,FIGN,RNASE1,ELP2,RPS6KA2,MEG3,SEC14L1,SGK1,FAM102A,PPM1E,SLC6A8,SLC9A5,SLC12A2,COA1,IFT122,PDZRN3,SOX3,SPART,DIP2A,KANK1,NECAB1,PLCB1,TMEM150C,SYT1,TCF4,TRIM2,PCDHB10,PCDHB7,BEX4,SYNPO2,RUNDC3B,TRPS1,RPRM,TOM1L2,VLDLR,PRTFDC1,TUBA1A,DOCK8,TIGD6,FRMD6,DPF3,CPNE4,SPATA13" Coexpression M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.40E-07 3.87E-03 2.74E-05 2.72E-04 84 435 "NDRG2,ADCY8,ADRB2,SPARCL1,LTBP4,SEMA7A,PRX,TMEFF1,ARRB1,NUMB,ATP2A2,ALDH7A1,MPDZ,PROM1,KALRN,CDO1,RAB28,QKI,CNTN1,AKAP12,RIPOR2,SPOCK2,ARMCX2,HEPH,DNM1,EDN1,EDNRB,PLEKHA1,CALCRL,EPB41,EPB41L2,MTSS1L,FHL1,FOXF2,FLT1,FYN,SESN1,GFRA2,LYVE1,GLUL,FERMT2,STMN2,GSN,PSIP1,GUCY1B1,HP,IL6ST,ITPKB,KIT,LAMA2,LIFR,LMO2,MAP4,MAPT,MATN2,MEF2C,MEIS1,KITLG,MYO6,ENPP2,GNG2,FXYD1,PLTP,PMP22,SEPT4,PKIA,PTCH1,PTPRB,PTPRD,ROBO1,SATB1,SCN7A,TNFRSF19,LIMCH1,SNCA,SOX11,SPTAN1,ST5,TCF4,TNS2,TEK,TIAM1,HEY1,TUBA1A" Coexpression M8591 Genes up-regulated in cells sorted as ITGAX int [GeneID=3687]: EMR1 high [GeneID=2015] macrophages versus EMR1 int [GeneID=2015] dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 3.61E-07 4.10E-03 2.89E-05 2.87E-04 43 174 "TBC1D14,ARRB1,MARCH3,ATP1A3,GPR146,KSR1,SYNJ2,CAMK2G,SLC25A14,SH2B1,PDE4DIP,C2CD2L,DPYSL2,SNX29,EXTL2,PRMT5,BAIAP2,AGAP2,ANKFY1,TMEM175,INPP5K,MSL3,COQ10A,P2RX7,TREM2,PFKFB2,ING3,RETREG2,CNNM2,TMEM104,ZDHHC14,UBR7,ADAL,RASA3,MBD5,TAL1,TIAM1,LRRC8A,KAT6B,CDK20,SH3GLB2,INTS3,TUBA1A" Coexpression 15785748-Table3 Human Uterine_Santin05_178genes GeneSigDB 3.69E-07 4.20E-03 2.93E-05 2.91E-04 39 151 "SPARCL1,PDE8B,DST,IL33,RUNX1T1,LDB2,GPRASP1,RIPOR2,HEPH,CHRDL1,DYNC1I1,DPP6,ECM2,EDNRA,EDNRB,LRRC17,ABCA8,PRUNE2,STON1,GUCY1A1,HLF,IGF1,KCNB1,MATN2,MEF2C,NTRK2,ENPP2,ABCB1,PLCL1,FXYD1,PMP22,MAPK10,PTN,PDZRN3,ZEB1,TNS2,TEK,RUNDC3B,FLRT2" Coexpression M2116 Genes correlated with neural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.06E-07 4.61E-03 3.20E-05 3.18E-04 35 129 "NDRG2,BCAS1,ARRB1,CA4,CAMK2G,CCK,CDR1,CHN1,CPNE6,NSL1,CRYM,DYNC1I1,EDIL3,ANKRD46,ACSL4,HPCAL4,FAM49B,FUT9,GABARAPL2,MBP,LYRM9,ENPP2,SERPINI1,PLCL1,FXYD1,SCHIP1,PPP1R1A,PRPSAP2,ROGDI,SH3GL3,USP33,AGTPBP1,SGK3,UGT8,ANKS1B" Coexpression 18794137-SuppTable1a Human Breast_Creighton08_772genes GeneSigDB 4.82E-07 5.47E-03 3.75E-05 3.72E-04 94 507 "NCKAP5,KIAA1324,OSBPL6,SEMA6A,GPRASP2,OGT,APBB2,ZBTB10,BARD1,BCS1L,DST,RAB29,WASF1,CA12,ARHGEF2,CDC25B,LARGE1,EPS15L1,FAM189A2,HOMER3,COL4A5,GREB1,RIMS2,DCAF4,TCAF1,ARHGAP24,TBC1D5,DTNA,MAMLD1,FARSB,SEMA3D,EGR3,ERBB4,ARMCX1,DLC1,PRMT5,OLFM1,TMEM164,FHL1,EVL,ZBED3,SPIN1,RAB30,GPER1,GRIA2,ARHGAP36,IPO5,L1CAM,LAMP2,SYTL4,MAP4,MAPT,MEST,THYN1,MYO5A,NRCAM,SNX10,KCTD15,PMP22,PPP2R5E,ELOVL2,PTPRG,ACSS3,RBBP8,ELP2,CCDC112,SARS,SHMT2,SYBU,ZFP1,SOX3,ERC1,CEP68,NECAB1,PLCB1,SYT1,ANKRD28,MMS19,CAMTA1,TBL1X,TIAM1,SYNPO2,METTL3,SGK3,VGF,ZIC2,ZNF711,LYPD6,DHX33,SLC38A1,SEMA3B,FZD3,DOCK8,FRMD6" Coexpression M12135 Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.82E-07 5.47E-03 3.75E-05 3.72E-04 41 164 "ABCD2,CADPS,RNF182,CFL2,LY86,CNR1,CSF1R,UBXN2A,PNPLA8,KIAA0408,HDAC9,TCAF1,SCRN1,BRINP1,JAKMIP2,EDNRB,APC2,SCARA3,NSG1,FYN,ZMAT1,ACSS1,KIAA1841,STMN2,FRMD5,IGFBPL1,MAP2,MYT1,PKIA,SKOR1,MAPK10,RGS4,RNH1,ATAT1,RTN1,SATB1,KIF21A,RHBDL3,TAL1,SGK3,FSTL5" Coexpression M6018 Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (6h). MSigDB C7: Immunologic Signatures (v6.0) 5.17E-07 5.87E-03 3.90E-05 3.87E-04 47 200 "FAM135A,ZBTB10,BBS2,KSR1,SUMF2,AKAP5,OSBPL3,KIAA0040,UBXN2A,EARS2,TBC1D5,KIAA0753,TMCC2,EGR3,SRPK3,GPHN,CHST15,FKTN,GTF2IRD2,POMT1,ST6GALNAC3,GAD1,DCLK2,PARD3B,ZNF496,CHIC1,ZNF862,EXOSC10,PPM1B,MTMR10,PTK2,GTDC1,CCDC82,ZNF532,MAPK12,SCN8A,ZFP2,ATF7IP,FAM126B,DOP1A,DNMBP,DMXL2,FRYL,RGMB,TRPM2,TTC3,ZFP41" Coexpression M8954 Genes up-regulated in T conv from lymph node of elderly (retired breeder) mice: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.17E-07 5.87E-03 3.90E-05 3.87E-04 47 200 "AP2A2,TNRC6C,N4BP2L1,BBS2,SYNJ1,FOXN3,IPCEF1,SOCS5,KIAA0040,ARHGEF4,IP6K1,ZC3H11A,SLC12A6,KMT5B,PLEKHA1,CHST15,HRASLS5,RAPGEF6,SESN1,GPR75,TNRC6A,KCNMB4,INSYN1,BACH2,KHK,LAMA2,PAXBP1,HECTD2,NCOA7,SMAD1,MBP,TM6SF1,NCF2,NLGN3,TMIE,SNRK,CEP97,ZMAT4,SLC25A36,CCDC82,RCOR3,FAM126B,NR2C2,SSBP2,TTC3,RNF170,FRMD6" Coexpression M8115 Genes up-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by IL10 [GeneID=3586] versus NFKB1 [GeneID=4790] knockout macrophages stimulated by IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 5.17E-07 5.87E-03 3.90E-05 3.87E-04 47 200 "TBC1D14,PDZD4,MAP4K3,KCNAB2,TMEFF1,CDK13,ATP6V0A1,KIF1A,GPR146,GAL3ST1,NCOR1,MYADM,FBXL5,CD99L2,SEMA3D,TNK2,EPB41L2,CDKL3,FAM198B,PDLIM5,GAD1,SRCAP,KCNMB4,TOX2,MIER3,IL6ST,KIFC3,SMAD9,MBD1,KCTD6,MYO5A,PIK3R1,GPSM2,PLTP,PTK2,PTPRN2,WDR37,MYO16,CLASP2,TCF4,PIK3R5,UCHL1,PLEKHH2,KCNK12,AMZ1,KLHDC1,RNF146" Coexpression M6554 Genes down-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 5.17E-07 5.87E-03 3.90E-05 3.87E-04 47 200 "HACE1,CARNS1,EIF4G3,STX16,BACH1,LDLRAD4,CACNA2D2,PCYT1B,SH2B1,PDE4DIP,HDAC9,IP6K1,CPEB2,SLC43A2,PRKAG2,SUCO,ZNF274,GLUL,L1CAM,PAXBP1,GPR155,MAN2A2,MATK,MATN2,ZNF862,PIK3R1,PLCL1,ANKRD16,PTPN13,RFX3,CYB561D1,MCMBP,RYR3,PEAR1,SCAF8,ANKRD6,MPRIP,STX1A,FBXW11,TRIM2,AKTIP,TIAM1,TUBB2A,MICU3,MSRB3,FRMD6,RNF146" Coexpression M2706 Genes up-regulated in primary epithelial breast cancer cell culture over-expressing E2F3 [Gene ID=1871] gene. MSigDB C6: Oncogenic Signatures (v6.0) 5.18E-07 5.89E-03 3.90E-05 3.87E-04 46 194 "ADGRB2,SYNGR3,NGEF,ABCG2,RAB26,TSPAN5,RASGRP1,PCOLCE2,ENO2,RAB9B,FGFR3,MEX3B,KHDRBS3,CSPG5,GAD1,TPPP,FAM222A,UBE2QL1,SOWAHA,LMO2,TM6SF1,NPTX1,GPR137C,TMOD2,SNX10,PTCH1,ZDHHC14,MAP6D1,SH3BGR,ZFP30,SLC4A3,GKAP1,PEG10,CDK19,SEPT3,SYN1,TMEM121,TIAM1,HEY1,UGT8,PDIA2,ZIC2,REEP1,EML6,SLC30A4,PLSCR4" Coexpression M13206 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.22E-07 5.93E-03 3.90E-05 3.87E-04 67 326 "XKR4,FMNL2,SPARCL1,IGDCC4,MYOM1,DST,DCLK1,LRRFIP1,FOXN3,MAGED1,NCOR2,CLIP3,CST3,BOC,JAKMIP2,ZNF804A,RHOBTB1,DLX1,CDON,EBF1,SEZ6L2,ING4,MFSD10,LRRC17,EYA1,DLC1,BAIAP2,AMOTL2,KCNMB4,ATP2B1-AS1,GSN,ATOH8,IGFBPL1,LMO2,MAP2,MEF2C,AFF1,NBL1,ZNF827,ENPP2,SMOX,PCDH18,RETREG2,LRRN3,PTH1R,PTX3,PID1,C1orf54,RGS3,ELP2,SATB1,ANKRD6,FAM214B,LIMCH1,DOK5,ZNF423,SPTAN1,ZBTB43,TSPYL2,LMO3,PHLDB1,SULF2,TRO,RPRM,UBE2H,ITM2C,FRMD6" Coexpression M768 Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.52E-07 6.27E-03 4.10E-05 4.06E-04 29 98 "NDRG2,SEMA6A,BIN1,PKP4,NCOA1,PTBP2,CACNA2D2,FOXN3,CNR1,PPP1R16B,DMPK,PLXNC1,NCALD,PIPOX,EYA1,TPPP3,PCDH17,KCNN3,MYCN,NRCAM,PKIA,PCMTD2,SIRT2,SOX11,POGZ,SYNE2,COBL,ZNF106,HEY1" Coexpression M253 Genes whose expression in suboptimally debulked ovarian tumors is associated with survival prognosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.77E-07 6.56E-03 4.26E-05 4.22E-04 94 509 "ADGRF5,SPARCL1,SPOP,AMH,APC,ADAM15,DST,SCAPER,MYRF,THSD7A,CAMK2A,RUNX1T1,CCNH,ARHGEF1,ARHGEF2,SEPT7,CCPG1,SRSF11,ABCG2,HOMER3,AKAP7,ARMC8,SNCAIP,CSF1,ARHGEF10,PHF14,GPRASP1,HDAC4,ZFYVE16,HEPH,FBXL5,DTNB,ECM2,EDNRA,SUGP2,DENND4A,F8,ABCA8,BAIAP2,CGREF1,GATM,SESN1,PCDH17,COPS8,GSTM5,IRAK3,ATXN2L,ACOT7,HMGCR,IL6ST,MATK,MEF2C,NBL1,CDK18,PDE4A,ENPP2,PIK3R1,CCSER2,PPP3CA,VPS13C,PTPRD,PTPRN2,RAD17,CCDC40,FAT4,REV3L,ATP8B4,RPS6KA2,SBF1,FNDC3A,SLC12A4,CDK5RAP2,LIMCH1,PDZRN3,SPATA7,CDK19,SPART,SS18,EXOC7,IQCE,ZEB1,SYNE1,OBSL1,SIRT1,CHST8,TIAM1,METTL3,VAV1,KCNK12,USP32P2,KCNAB1,PDSS2,ADAMTSL3,AAAS" Coexpression 17880687-TableS5 Human Embryo_Heim07_327genes GeneSigDB 6.09E-07 6.92E-03 4.46E-05 4.42E-04 57 263 "CLK4,TAOK1,SPOP,PKP4,KIF1A,BACH1,CACNA2D1,PTBP2,RUNX1T1,SEPT7,HECTD1,AHCTF1,FAM171B,CSNK1G3,TMEM170A,DBT,YTHDC1,FEM1B,FCF1,EGFR,EPB41,FGF12,NBEA,UFM1,GCNT2,TNRC6A,ZNF638,KCNMB4,GNG4,GPD2,GRM8,RASSF8,MIER3,IBA57,LIMS1,PPM1L,CCDC13,NFYA,CNOT4,SLC11A2,ZNF655,PURG,PTPRG,USP47,DCUN1D2,GSTCD,CLIP1,RTN1,FNIP1,SGK1,CHD9,FNDC3A,PEG10,PRRC2C,MAP3K12,TMEM178A,SOCS4" Coexpression M2239 Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.17E-07 7.01E-03 4.50E-05 4.46E-04 68 334 "AXIN2,OSBPL8,AK2,ALCAM,ZFYVE28,CDK13,DST,FUBP1,RAB28,RCHY1,NECTIN3,CREM,ARHGEF10,SOCS5,DOCK4,TCAF1,TSPAN5,FSD1L,SRRM1,GORAB,SEC24B,SYNCRIP,ATP2C1,GCNT2,TCERG1,RASSF8,ELOVL5,AGFG1,RBPJ,IPO5,MAP2,MBNL1,COMMD5,NFYA,OPA1,XRN1,PPP2R5E,PPP3CA,PTK2,PTPRG,C1orf109,RAP1GDS1,OXR1,FIGN,ZNF532,SEPHS1,LIMCH1,KIF13A,TRERF1,MYCBP2,RBM26,TROVE2,VPS13A,AGTPBP1,NR2F1-AS1,DOCK9,SLC44A1,CBX5,TMPO,RUNDC3B,SSBP2,UBE3A,WIPF1,ZNF184,HNRNPA3,MSRB3,FXR1,FRMD6" Coexpression M16909 Genes up-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [GeneID=2475]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.40E-07 7.27E-03 4.63E-05 4.59E-04 102 566 "ADCY8,AP2A2,C1QTNF1,SRPX,LTBP4,BIN1,DDO,MADD,ARRB1,SLC4A4,ALDH7A1,MPDZ,BCHE,GYG2,CAST,SPAG9,CD86,CDO1,RCBTB2,PDE4DIP,CTH,TM9SF4,GIT2,DBT,FAM13A,IRAK4,MFSD10,GPHN,EZH1,FCGRT,PRKAG2,IP6K2,IQCG,EVL,CINP,OGA,TMEM8B,CYP46A1,PRRC2B,GSTT2,PSIP1,HMGCL,IDH3B,IFI16,ITGA7,JAK2,LAMA2,LYRM9,SLC11A2,PCDH9,CDK18,PDE4A,SEPT4,POLG,PPARA,PPP3CA,CNNM2,SAMD9,BCAS3,VPS13C,USP47,ZCWPW1,OXR1,RDX,RIC8B,RTN1,DGLUCY,COPZ1,SHMT2,AMBRA1,ST6GAL1,DHX30,SLC6A8,CDK5RAP3,ATF7IP,INTS9,IFT122,KDM4B,ARHGAP26,LHPP,ST5,APOM,DIP2A,SUPT5H,SYNE2,PLCB1,SYT1,IQCE,TCF4,SYNE1,DOCK9,NSD1,ZNF34,KAT6B,CABIN1,TRPM2,TSC2,ZKSCAN5,ZNF142,ZNF154,HPS4,KAT6A" Coexpression 18593951-TableS3 Human Ovarian_Bonome08_572genes GeneSigDB 6.87E-07 7.80E-03 4.94E-05 4.90E-04 93 504 "ADGRF5,SPARCL1,SPOP,AMH,APC,ADAM15,DST,SCAPER,THSD7A,CAMK2A,RUNX1T1,CCNH,ARHGEF1,ARHGEF2,SEPT7,SRSF11,ABCG2,HOMER3,AKAP7,ARMC8,SNCAIP,CSF1,ARHGEF10,PHF14,GPRASP1,HDAC4,ZFYVE16,HEPH,FBXL5,DTNB,ECM2,EDNRA,SUGP2,DENND4A,F8,ABCA8,BAIAP2,FOXO3,CGREF1,GATM,SESN1,PCDH17,COPS8,GSTM5,IRAK3,ATXN2L,ACOT7,HMGCR,IL6ST,MATK,MEF2C,NBL1,CDK18,PDE4A,ENPP2,PIK3R1,CCSER2,MINDY2,PPP3CA,VPS13C,PTPRD,PTPRN2,RAD17,CCDC40,FAT4,REV3L,ATP8B4,RPS6KA2,SBF1,FNDC3A,SLC12A4,CDK5RAP2,LIMCH1,PDZRN3,SPATA7,CDK19,SPART,SS18,EXOC7,IQCE,ZEB1,SYNE1,OBSL1,SIRT1,CHST8,TIAM1,METTL3,VAV1,KCNK12,KCNAB1,PDSS2,ADAMTSL3,AAAS" Coexpression M2107 Genes whose expression significantly and positively correlated with oligodendrocyte density in layer VI of BA9 brain region in patients with bipolar disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.10E-07 8.06E-03 5.07E-05 5.03E-04 118 681 "ACADM,ADD1,ALCAM,BIN1,APLP1,FAM131A,ATP1A3,ATP2A2,ADGRB2,NAE1,BAIAP3,CACNA1A,CAMK2B,CAMK2G,CCK,SYNGR3,ENTPD6,ARHGEF2,MYL6B,CLTB,SULT4A1,MAGED1,MYRIP,CRMP1,CLIP3,CRYM,SLITRK5,PPP1R16B,SCRN1,IP6K1,ARMCX2,DCTN1,ELMO1,SEC16A,CHRDL1,DNM1,DPYSL2,ABCC5,OPTN,ENO2,RCAN2,TUBB3,CORO2B,CHST15,FGFR3,FHL1,ATP5PD,UBE2E3,RASL10A,STAU2,OGA,GABBR1,CHL1,GPR162,RUNDC3A,RAB40B,PRRC2B,PRUNE2,PTPRT,GABARAPL2,MSL1,IDH3B,ITPKA,KCNF1,MAN2A2,MAPT,PTOV1,LYRM9,NACA,NELL2,NNAT,NPY,NPTX1,DPY19L2P2,SERPINI1,PKM,PLCD1,NECAB2,MAPK9,RELN,NDUFS7,PTPRN2,RNH1,RTN1,SARS,TRA2B,PUF60,FAM102A,R3HDM2,SMARCC2,SMARCD3,NMNAT2,PEG10,LMO3,SST,SEPT8,STX1A,STXBP1,SYP,COBL,TAF6,PHF24,PUM2,BEX4,CABIN1,WBP2,RUNDC3B,RUSC1,TUBB2A,UBC,UCHL1,VSNL1,ATP6V0E2,NDRG4,RNF103,NELFE,HNRNPA3,AP3B2" Coexpression 20460542-SuppTable1 Human Colon_Dessein10_744genes GeneSigDB 7.55E-07 8.58E-03 5.36E-05 5.32E-04 119 689 "ASPHD1,ASIC1,FMNL2,ELFN2,AGT,CEP126,CARNS1,GPRASP2,SYT13,AMT,BCAS1,AQP6,SEMA4G,ARSE,CHRD,PROM1,DST,GPC2,DDR1,LONRF2,RAB26,AKAP7,COL9A3,GAL3ST1,AHCTF1,SEC31B,CDC42BPB,CRYM,CNTNAP2,DZIP3,GPRASP1,MYADM,DBN1,HEPH,MYEF2,FAM107B,SEC16A,ARRDC4,ABCC5,SEZ6L2,KLHL5,PHF20L1,EPB41L2,F5,FDFT1,PPP1R1B,FGFR3,MEX3B,EVL,OGA,GCNT2,ADAM28,TOX3,RAB40B,GRB10,DIDO1,PARD3B,ADAMTS13,ATE1,GSN,GSTT2,ADAMTS6,SLC2A6,ZHX1,ITGA7,KHK,LSS,MBNL1,AFF1,NRBP2,NPR2,NUCB2,OPA1,PALM,PDE4A,PFKFB2,SNX10,TMEM38A,PRIMPOL,TATDN3,SLC26A11,PRODH,ZNF493,PRRT2,ZNF532,HKDC1,ST6GAL1,LIMS2,SLC12A2,ZNF334,BTBD7,RCOR3,KIF13A,TMCC1,TRERF1,FNBP1,THSD1,ZC4H2,STX1A,KLHL7,ARHGEF9,ARC,ASTN2,TACC1,PCDHGA2,THRA,TPM1,STXBP4,ANKRD20A2,CCDC14,CLDND1,NPDC1,ZNF138,ZNF177,HNRNPA3,GJC2,NLRP3,FXR1,SENP7" Coexpression 17483311-SuppTable2 Human Brain_Beier07_320genes GeneSigDB 7.89E-07 8.96E-03 5.57E-05 5.52E-04 49 215 "SYS1,GALNT16,C1QTNF3,LRCH2,ZBTB10,SLC4A4,CFLAR,PROM1,SYNJ2,CACNA1A,SOCS6,STOML1,AKAP7,COL9A3,RTTN,NRG2,KIAA0040,ZFYVE16,FAM13A,HSD17B14,ERBB2,FDFT1,FGFR3,MPP6,GABBR1,LNX1,PLPP7,ADAMTS6,HNMT,INPP1,KHK,PAXBP1,MATN2,MID1,NELL2,DNHD1,SLC11A2,PIK3C2A,CCSER2,PLTP,MTRF1L,OXR1,ZFHX4,ZNF532,KIF21A,MESP1,KIAA0930,OBSL1,TCEAL7" Coexpression M4654 Genes up-regulated in comparison of naive CD8 T cells versus PD-1 high CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.24E-07 9.36E-03 5.78E-05 5.73E-04 46 197 "ATP6V0E2-AS1,ACTN1,RNF157,GPRASP2,ZBTB10,CARS,NOG,IPCEF1,ARHGEF4,USP6NL,C3orf18,EPB41L2,SPEG,ARMCX1,SH3YL1,SCML2,HPCAL4,SARAF,ADGRA3,ZNF496,USP51,IL6R,IL6ST,SFXN5,ZNF667-AS1,MEST,NEXMIF,NELL2,NRCAM,PCSK5,RETREG1,FAM216A,LRRN3,CEP41,PKIA,FAM184A,BEND5,GAL3ST4,RFX2,CNKSR2,SPART,STXBP1,RNF175,PRRT1,LMF1,MICU3" Coexpression M4196 Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [GeneID=2146] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.56E-07 9.73E-03 5.97E-05 5.92E-04 166 1037 "ASIC1,AXIN2,ADRB2,AGT,SORCS2,MARCH4,OGT,SEMA7A,PPFIA4,KCNAB2,APBB2,RGS20,SLC4A4,ATP2A2,BACH1,CFLAR,JAZF1,CA12,PTBP2,CAST,SPAG9,USP6,SCARB1,CCPG1,NOG,UBE2L6,B4GALT6,SLIT2,PPT2,QKI,HOMER3,ARMC8,BAG4,CNRIP1,NECTIN3,CSF1,SOCS5,KIAA0040,UBXN2A,CTH,MYADM,KCTD8,PABPC5,DNAL1,CPEB2,RCAN1,ARRDC4,DNAJB6,FIS1,E2F6,EDN1,ANKRD46,SEMA3D,OPTN,PHF20L1,SUGP2,EIF5,APC2,RPS6KC1,ST3GAL6,FGF1,BAIAP2,POLK,ANKFY1,SLC37A3,CGREF1,FYB1,ERAP1,GCNT2,GHR,MAP7D2,FERMT2,GPER1,GPR37,GRB10,ADAMTS6,ZHX1,FRMD5,BACH2,IFI16,RBPJ,IL6R,IL6ST,FAM69A,JAK2,KCNB1,KPNA5,LAMP2,LMO2,NCOA7,LSS,SMAD1,GPR155,MAP2,AQP11,MATN2,MATN3,SHC3,MEIS2,MEST,KITLG,POC1B,MSI1,MT1M,MX1,MXI1,NCF2,NPTX1,OXTR,PFKFB2,PFKFB4,SERPINI1,XRN1,SCHIP1,PPP3CC,VSTM2L,PRKAB2,PKIA,SAMD9,WBP1L,ZSCAN32,PTX3,TMEM145,TTC13,QDPR,C1orf54,SUSD4,RBBP6,REV3L,RGS4,SLC25A36,ZFHX4,ROBO1,AP1AR,SCP2,MRAS,SGK1,FAM102A,CCDC88A,SLC22A4,TMCC1,KDM3A,KDM4C,ZNF302,THSD1,NXT2,RGL1,NECAB1,SLC37A2,KLHL4,TCF4,SYNE1,TK2,LRRC8A,TP53BP2,TPM1,RGMB,TUBB2A,HIRA,XRCC4,PPP1R3F,ITM2C,FBXO36,NLRP3,FRMD6,NETO2" Coexpression 18537972-TableS3 Human Leukemia_San Jose-Eneriz08_772genes GeneSigDB 8.62E-07 9.79E-03 5.97E-05 5.92E-04 115 662 "RALGAPA1,CLK4,ADCY8,AP2A2,SPARCL1,SEMA6A,SYT13,APBB2,BCAS1,CDC14B,ARHGDIG,RASL11B,EIF4G3,N4BP2L1,AZGP1,SYNJ2,SCAPER,BAIAP3,CALM1,KALRN,CAMK2B,SLC25A14,HIP1R,CBLN1,CBS,MTMR7,ARHGEF2,DLGAP2,SOCS6,PCYT1B,COL11A2,CSF1,PPP6R2,ARHGAP24,HDAC4,MAML1,BRINP1,EXOG,MED12,RCAN1,EDIL3,CELSR3,PHF20L1,SUGP2,EGFR,SRRM1,ZNF391,EYA1,ZMYND10,ZNF589,SYNCRIP,AKAP3,SRCAP,LYVE1,SPIN1,GRM2,AP4S1,NCKAP1L,HMGCL,HNMT,DHX35,TJAP1,INPP5B,CDH20,KCND1,PACRG,ADAM22,MSR1,FXYD7,NF1,NTRK3,PIK3R1,ZFYVE21,MTRF1L,MAPKAP1,POLG,PPP1R1A,PPP3CC,PTN,RASGRF1,TRIM68,NUDT11,PBRM1,KIRREL1,ZNF671,SATB1,FNIP1,SUPT20H,TRA2B,R3HDM2,SLC11A1,ATF7IP,KDM4B,TSNAXIP1,SOX11,ZSWIM8,SPTAN1,NFASC,ATP10B,TROVE2,SSTR2,ARHGEF9,SYT5,EXOC7,IQCE,SIK3,TEK,ZFPM2,CHST8,TK2,TRIO,PDSS1,ZNF45,ANKS1B,ZNF37BP" Coexpression M6920 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.79E-07 9.99E-03 6.02E-05 5.96E-04 29 100 "NDRG3,ADCY6,OSBPL1A,SEMA7A,CADPS,MPDZ,CCK,TSPAN5,TUBB3,OLFM1,FGF12,SYT17,CPLX1,STMN2,ACOT7,SMAP1,STMN1,MEF2C,MMP16,NEFM,NPY,SERPINI1,PTPRD,FBXW7,SST,SSTR2,STX1A,SYP,NACC2" Coexpression M14228 Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.79E-07 9.99E-03 6.02E-05 5.96E-04 29 100 "AS3MT,ADD2,KIAA1211,RNF150,SYT13,LGR5,TMEM108,ADAM23,CLDN10,COL9A3,DLX1,DMD,PCOLCE2,OLFM1,MAP7D2,LIFR,LSAMP,MYCN,NPTX2,NRCAM,CLDN11,LAMA1,PTX3,ANKRD6,PEG10,SYNPO2,UCHL1,ZIC2,ZNF711" Coexpression M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.38E-07 1.07E-02 6.38E-05 6.33E-04 56 260 "SRPX,OGT,ANK2,GAS7,ASPA,SGCE,DCLK1,CDO1,SLIT2,ABI3BP,SUSD5,VCAN,PDE4DIP,HDAC4,SCRN1,CHRDL1,ECM2,EGFR,TENM1,PCOLCE2,LRRC17,ABCA8,SCARA3,CHL1,GSN,GSTM5,HNMT,IGF1,FAM69A,KCND2,LAMA2,MBP,LRP1B,MEIS1,MEIS2,MEST,MITF,NOVA1,NTRK2,PCDH9,FXYD1,PLTP,ELOVL2,PTPN13,PTPRD,PTPRG,PTX3,PID1,ROBO1,ATP8B4,MEG3,DZIP1,PEG10,KIAA0930,TRO,FLRT2" Coexpression 18714397-TableW1 Human Ovarian_Park08_77genes GeneSigDB 9.65E-07 1.10E-02 6.52E-05 6.47E-04 21 60 "CLK4,SPARCL1,CAMK2G,CAST,MS4A7,BOC,ECM2,EDIL3,TUBD1,FAM198B,SCARA3,KIT,MEIS2,MX1,CNTN3,PIK3R1,RNASEL,CPEB4,LIMCH1,SULF2,ZEB1" Coexpression M2882 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.04E-06 1.18E-02 7.01E-05 6.95E-04 59 280 "FMNL2,NME5,C1QTNF1,PLA2G4C,BMP7,CALB1,KCNAB3,DLGAP2,CDR1,CHGB,CSF2RA,ERC2,DOCK4,ARHGAP24,SNAP91,DYNC1I1,RCAN2,ETV1,REEP2,ST3GAL6,GABRA3,TOX3,GPR37,HAS2,ITPKA,KCNH2,KCNK3,KIF5A,KIT,MMP17,TAGLN3,NRCAM,NTRK3,PCDH8,PCDH9,MAPK10,DIRAS2,RELN,PTX3,RNASE1,RTN1,SATB1,LIMCH1,SNAP25,NMNAT2,SPP1,LMO3,CLSTN2,STX1A,SYT1,DNMBP,ZEB1,TRIM2,HEY1,TLR4,UGT8,WNT7A,MKRN3,NAV3" Coexpression 16849537-SuppTable3 Human StemCell_Davicioni06_389genes GeneSigDB 1.05E-06 1.19E-02 7.01E-05 6.95E-04 65 319 "ADD1,ADORA1,SPARCL1,ALK,ANK2,PPFIA4,TMEFF1,ARRB1,MARCH3,BCHE,NRP2,ST3GAL5,MAP4K4,ARHGEF6,CREM,AKAP12,CSNK1E,SPOCK2,JAKMIP2,GSDME,RHOBTB1,E2F5,EDN3,EDNRA,PLXNC1,LRRC17,EYA1,RASL10A,DENND2A,GAD1,GATM,MSTN,PCDH17,MSL3,HMGCR,INPP1,FAM69A,ITPKB,KCNH2,KCNN3,SMAD1,MMP16,MN1,MYCN,NEFM,NRCAM,PCSK5,PDE4D,EPB41L4B,LRRN3,PKIA,SPDL1,PTPRE,MORC4,STK32B,MEG3,SATB1,GALNT10,SGK1,SOX11,NFASC,COBL,TCF4,DICER1,REEP1" Coexpression M1914 Genes up-regulated in neural stem cells (NSC) at 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.06E-06 1.20E-02 7.01E-05 6.95E-04 61 293 "ACTN1,NDRG3,AGT,SORCS2,APAF1,APBA2,APLP1,IGDCC4,KIF1A,CFLAR,RUNX1T1,CLDN10,USP2,CRLF1,RCHY1,CREM,AATK,SNCAIP,CSF1,CST3,IP6K1,DTNA,FCGRT,FGF1,OLFM1,BAIAP2,POLK,FOXO3,USP19,GRIA2,GSN,GSTM5,ZFYVE27,MEF2C,NELL2,NNAT,P2RY1,PALM,PDE1C,PKD1,TMEM38A,PLCD1,SMOX,PCDH18,SEPT4,GDPD2,PTPRE,PTPRO,RIPOR1,S100B,DGLUCY,ST6GAL1,SLC4A3,CPEB4,SPP1,SULF2,SYNE1,ZMAT3,THRA,NACC2,NDRG4" Coexpression M14566 Genes up-regulated in HMEC cells (primary mammary epithelium) upon expression of both of TP53 [GeneID=7157] and the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vectors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.10E-06 1.25E-02 7.25E-05 7.18E-04 47 205 "ABHD6,APAF1,TNRC6C,ARRB1,MARCH3,KSR1,CABP7,CAPN3,NPIPA1,SLIT2,ARHGEF6,WHRN,COL9A3,ZNF385A,PPP1R16B,RASGRP1,FRY,APC2,FGF13,FOXF2,SEMA4D,OGA,GPT2,GPR37,UBE2QL1,SHISAL1,KCNK3,SMAD9,MX1,NPTX1,PCSK5,PLCD1,EPB41L4B,PPP2R2C,PTX3,RET,HUNK,ARX,SHC4,NBPF1,UNC5B,TACC1,ZIC2,REEP1,STOX2,ST8SIA2,SPATA13" Coexpression M4526 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.11E-06 1.27E-02 7.28E-05 7.21E-04 46 199 "NDRG2,AP2A2,BIN1,AMT,ATP1A1,STX16,ST3GAL5,CFAP410,CAPN3,P2RX6,ARHGEF1,CDC25B,NPIPA1,COX4I1,SH2B1,SNPH,INTS1,SGSM2,DMTF1,KAT8,IP6K2,ERGIC3,SARAF,OGA,TMEM8B,USP19,RAB40B,MSL1,ITPKB,KCND1,KIT,MN1,SNRK,RGS12,R3HDM2,RCOR3,TTC17,FAIM2,MYCBP2,TSPYL2,ERBIN,CEP68,MCF2L,KAT6B,TTC3,KAT6A" Coexpression M7766 Genes up-regulated in macrophages 48h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.11E-06 1.27E-02 7.28E-05 7.21E-04 46 199 "C6orf89,USP2,ZMYM4,ABCG2,AKAP12,AATK,BOC,CHRDL1,EXTL2,EZH1,ST3GAL6,CHST15,FLNC,COQ5,GPD2,BVES,PADI2,IDH3A,IDH3B,SCIN,ITGA7,KLHL23,LAMA2,MAP4,CHIC1,PPM1L,NDP,NPR2,CCSER2,FXYD1,FITM2,RASGRF2,ZFHX4,MAPK12,SEMA6D,SMARCD3,SPTB,COBL,FRYL,AKTIP,TPM2,KCNE5,ATP6V0E2,TCEAL7,PDSS2,UBE3B" Coexpression M7762 Genes down-regulated in macrophages: wildtype versus MYD88 [GeneID=4615] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.29E-06 1.47E-02 8.30E-05 8.23E-04 46 200 "SPARCL1,ARHGAP20,TNRC6C,MTMR3,LDB2,AKAP12,AATK,SNCAIP,LRRC3B,SCRN1,CHRDL1,CDON,DTNA,EYA1,HSPA12B,NRN1,ST3GAL6,SCARA3,FLNC,GALNT15,GPD2,GSN,COQ10A,BVES,GUCY1B1,VSIG4,SLC35G1,KCNH2,KIT,MEST,NPR2,EPB41L4B,PCMTD2,ARMH4,SEMA6D,PRCD,LIMS2,NMNAT2,ADHFE1,KANK1,ERCC6L2,CA14,CCDC136,LYPD6,PROCA1,HRASLS" Coexpression M7548 Genes up-regulated in double positive thymocytes: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v6.0) 1.29E-06 1.47E-02 8.30E-05 8.23E-04 46 200 "EMILIN3,ARNTL,CADPS,LINC00847,SLC25A14,AKAP6,MYRIP,PHACTR3,MYADM,FSD1L,OPTN,DCTN4,AMOTL2,ZNF559,SYT17,KCNMB4,GRB10,SERP2,IFI16,NCOA7,LSAMP,MAP2,SRSF12,MYO5A,LRP12,GDPD1,TUG1,ROGDI,HKR1,ZNF671,ZFP2,KIF21A,WDR47,NAPB,LMBRD1,SSTR2,SYT1,TRIM2,PCDHB6,PCDHB3,TUBB2A,TSPAN11,ZNF711,ZNF177,CASC15,JPH3" Coexpression M5036 Genes up-regulated in comparison of SP3 thymocytes versus SP4 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.29E-06 1.47E-02 8.30E-05 8.23E-04 46 200 "OSBPL1A,ARMC12,APBB2,ALDH7A1,BCHE,KALRN,CAMK2A,EVI5L,PPT2,CNN3,ZNF385A,SPOCK3,NYAP1,ABCC5,TNK2,CEP78,UBE2E3,CHL1,GPR162,TOX3,CBX1,ADGRA3,HAS2,VSIG4,TJAP1,MPP2,PTOV1,MXI1,NEXMIF,PALM,DUSP26,PURG,TMEM255A,FAM184A,ZDHHC14,SATB1,ARX,SSPO,HIF3A,VWCE,PRRT1,IL34,KCNE5,SSBP2,STOX2,TUBA1A" Coexpression M2726 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.31E-06 1.49E-02 8.37E-05 8.30E-04 45 194 "KIAA1324,ALCAM,PKP4,APBB2,SHROOM2,CASK,ZBTB10,MPDZ,CA12,CALB2,PTBP2,COL9A3,LRIG1,GREB1,GAPVD1,RASGRP1,EGR3,EPB41L2,TBC1D16,DLC1,CHST15,GALC,GHR,SPIN1,GPD2,GPER1,DIDO1,JAK2,KITLG,MXI1,FAM216A,PMP22,EPB41L4B,ELOVL2,ROBO1,PPM1E,BTBD3,SOX3,PLCB1,SATB2,TCF12,TRPS1,ZNF32,FTSJ1,JMJD1C" Coexpression M12522 The 'group 1 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.52E-06 1.72E-02 9.61E-05 9.53E-04 95 527 "NCKAP5,KIAA1324,OSBPL6,SEMA6A,GPRASP2,OGT,APBB2,ZBTB10,BARD1,BCS1L,DST,RAB29,WASF1,CA12,VXN,ARHGEF2,CDC25B,LARGE1,EPS15L1,FAM189A2,HOMER3,COL4A5,GREB1,RIMS2,DCAF4,TCAF1,ARHGAP24,TBC1D5,DTNA,MAMLD1,FARSB,E2F6,EGR3,ERBB4,ARMCX1,DLC1,PRMT5,OLFM1,TMEM164,FHL1,EVL,ZBED3,SPIN1,GPER1,GRIA2,ARHGAP36,IPO5,L1CAM,LAMP2,SYTL4,MAP4,MAPT,MEST,THYN1,MYO5A,NRCAM,SNX10,KCTD15,PMP22,PPP2R5E,ELOVL2,PTPRG,ACSS3,RBBP8,ELP2,CCDC112,SARS,SHMT2,SYBU,ZFP1,SOX3,ERC1,CEP68,NECAB1,PLCB1,SYT1,ANKRD28,MMS19,CAMTA1,TBL1X,PCDHGA4,TIAM1,SYNPO2,METTL3,SGK3,FAM155A,VGF,ZIC2,ZNF711,LYPD6,DHX33,SLC38A1,SEMA3B,DOCK8,FRMD6" Coexpression M9245 Genes up-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]. MSigDB C7: Immunologic Signatures (v6.0) 1.52E-06 1.73E-02 9.61E-05 9.53E-04 45 195 "INTS2,CEP126,MADD,ZSCAN18,EIF4G3,DDR1,CHN2,ABCG1,DZIP3,ARHGAP24,TBC1D5,GIT2,ELMSAN1,DMD,TOM1,EPB41,RASGRP2,TMEM164,CELF1,TVP23A,GABBR1,DCLK2,CLASRP,BACH2,IFI16,ITGAM,STXBP5,ZFYVE27,BLOC1S2,PRKACB,VPS13C,RIPOR1,TMEM231,MARCH1,KHDRBS2,GTDC1,SATB1,FAM81A,PDLIM2,SIK3,ARL10,ZNF610,LAT2,ZNF28,MAP3K12" Coexpression 20220088-SuppTable1 Human Immune_Allen10_2900genes GeneSigDB 1.56E-06 1.77E-02 9.78E-05 9.70E-04 263 1798 "RALGAPA1,ACADM,NCKAP5,FMNL2,BRAP,ESYT2,OSBPL1A,OSBPL6,ALCAM,BBOX1,GPRASP2,OGT,KCNAB2,CDC14B,SFMBT2,CASK,MARCH3,ZSCAN18,CCAR2,EIF4G3,N4BP2L1,ATP6V0A1,CFLAR,BMP7,DST,CA12,DDR1,PTBP2,SLC25A14,HIP1R,RUNX1T1,ARHGEF2,L3MBTL4,MAGI1,RCBTB2,FOXN3,RAB28,CLTB,TMEM184B,CNN3,FAM149A,ANKRD35,AKAP5,SLC4A8,ZFP28,C2CD2,SNCAIP,LRIG1,OSBPL3,PDE4DIP,PITPNM3,ARHGEF4,PUM1,USP6NL,FAM131B,CYBB,HDAC9,MYADM,ARHGAP32,TCAF1,RIPOR2,ARHGAP24,HDAC4,DGKG,MYEF2,MFAP3L,GSDME,RPS6KL1,DPP6,DPYSL2,DTNA,SNX29,TSPAN5,EDN3,ANKRD46,HIPK3,FEM1B,SEMA3D,OPTN,EBI3,EGFR,KMT5B,AASS,KCTD3,ENO2,EPB41,ERBB2,SIRPB1,KATNAL1,FAM198B,TBC1D16,FCGR1A,ST3GAL6,FER,FGFR3,BAIAP2,MEX3B,PCYOX1,ATP13A4,FLT1,SPECC1,STAMBP,DOT1L,MPP6,OGA,FYN,GABBR1,CHL1,IQGAP2,ERAP1,TMEM8B,GGTA1P,PPARGC1A,GLUL,KIAA1958,RAB40B,GNAL,LOXL3,GNAO1,LILRA2,TPPP,GUCY1A1,GUCY1B1,IRAK3,PADI2,ZHX1,HLF,SYNPO,HMGCR,AGFG1,IRF8,LRRC25,LRRCC1,IBA57,ITGAM,CDH20,KIT,STMN1,SMAD1,PIK3AP1,GPR155,MAN2A2,MAP2,MAP4,MBNL1,MEF2C,MEIS1,PPM1L,AFF1,LAYN,MYO6,NBL1,NEFM,NEK1,NFIX,NOVA1,NPTX2,NRCAM,OCRL,P2RY1,PDPK1,CCSER2,ZFYVE21,PKM,KCTD15,GPSM2,PLTP,PSAT1,EPB41L4B,SH3KBP1,PPP2R2C,PRKAR1B,PRKCB,GRAMD1C,PTCH1,PTPRE,PTX3,SUSD4,ROGDI,RASGRF1,RDX,MORC4,GTDC1,PBRM1,RNH1,CYB561D1,ROBO1,CCDC25,ATP8B4,RPS6KA2,ZNF568,AP1AR,SEMA6D,TNFRSF19,KIF27,FERMT1,ASAP3,WDR47,SLC6A8,SEPHS1,MTERF2,GKAP1,SMARCA4,LIMCH1,KIF13A,TMCC1,FAM126B,SPP1,TEX2,ERC1,UNC5B,IQSEC2,SPART,PBLD,SAMSN1,SOX21-AS1,MPRIP,ELOVL4,SEPT8,KANK1,KLHL7,SYNE2,DNMBP,TBL1X,ATMIN,ZEB1,TCF12,DOCK9,OBSL1,NSD1,GPRIN3,SIK3,VWCE,ZMAT3,AKTIP,SLC44A1,TIAM1,TLR4,PARD3,TPM2,TRIO,RUSC1,SSBP2,TUBB2A,USP1,VSNL1,CLIP2,LAT2,CLDND1,RICTOR,ZNF711,NDRG4,SPIRE1,UPF3A,STOX2,CIAPIN1,ITM2C,TRIM16L,EPM2A,NLRP3,FRMD6,DPF3,GAN" Coexpression 20386565-TableS1 Human Prostate_Zhao10_1841genes GeneSigDB 1.60E-06 1.81E-02 9.97E-05 9.88E-04 109 627 "ADD1,SEMA6A,AMPD2,BCAS1,ARRB2,DYNLL1,ATP1B3,N4BP2L1,BACH1,CA12,SPAG9,KRIT1,CCNT1,LRRFIP1,TPP1,CLTB,FBXO7,COX4I1,CREM,ENTPD4,VCAN,CST3,GREB1,POM121,DTNA,ABCC5,EDNRA,HIPK3,SUGP2,EIF4G1,ELN,ERBB2,EZH1,TUBA1B,PTK2B,CHST15,FGFR1,FHL1,VTI1B,FLNC,PDLIM5,KHDRBS3,CELF1,FYN,GAA,IQGAP2,MTHFD2,TUBGCP4,AHDC1,BRD8,STARD3,CBX1,GP1BB,PCLO,DIDO1,CLASRP,HBA1,ATXN2L,GABARAPL2,HP,MSL1,IL6R,IL6ST,SMAD1,MAPT,MATN2,MIA2,MSI1,NEFH,PIK3R1,MBOAT7,POLG,PPM1B,PRKAB2,PTCH1,PTN,PTPRN2,RBBP8,RDX,RNASE1,SEC14L1,SUPT20H,FAM102A,TMCC1,KDM3A,SPP1,CEP68,PHLDB1,ZC3H4,ANKRD12,FBXW11,TBL1X,TCF12,SIK3,TP53BP1,TPM1,TPM2,TRIO,RUNDC3B,RUSC1,HIRA,UBE3A,VGF,XPO1,REEP1,URM1,MPPE1,ST7,RTN4" Coexpression M1935 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation marks at k4 (H3K4me3) and K27 ((H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.65E-06 1.87E-02 1.02E-04 1.01E-03 36 142 "CCDC85A,ADORA1,UNC5A,SLC24A4,CBLN1,PLXNA4,CELSR3,FGF11,FLT1,ABLIM2,MEGF11,GAD1,GNAL,GRM8,ATOH8,FRMD5,KNDC1,LMO2,NEFM,PCDH8,PDE4A,PLTP,RASGEF1B,RELN,KHDRBS2,KLHDC8A,EPHA10,SATB1,NMNAT2,CHST8,CDH22,CSMD1,VGF,ELFN1,WNK2,ST8SIA2" Coexpression M2581 Genes up-regulated in the HSC supportive stromal cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.69E-06 1.92E-02 1.04E-04 1.04E-03 61 297 "RALGAPA1,NCKAP5,NDRG2,GALNT13,RNF150,SORCS2,ARRB1,SLC4A4,HCN2,THSD7A,UBE2L6,ARHGEF6,AKAP6,PYGO1,RASSF2,RHOBTB1,CALCRL,MTSS1L,SPEG,TVP23A,FYB1,B4GALNT1,DCLK2,GNAO1,PRUNE2,LPAR4,GPER1,BACH2,ZDHHC15,IGF1,MATN2,MEST,KITLG,MN1,NRBP2,NOVA1,NPR2,CDK18,PDE4D,PDE1B,PMP22,PRKAR1B,PTN,CASTOR1,PTX3,FAT4,OXR1,MORC4,RGS4,RORB,PEAR1,ST6GAL1,SPP1,SULF2,SYN1,ARC,SLC37A2,PCDHB15,TMEM121,ITGB3BP,ELFN1" Coexpression 18812457-Table2 Mouse Viral_Mercader08_51genes GeneSigDB 1.81E-06 2.06E-02 1.11E-04 1.10E-03 15 35 "ALCAM,CACNA1B,NCOR1,TENM1,ATP2C1,PPARGC1A,MALT1,KCND2,EML5,FIGN,RPE,SP4,PLCB1,SYT1,DMXL2" Coexpression M6757 Genes down-regulated in splenic CD 33D1+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.82E-06 2.07E-02 1.11E-04 1.10E-03 41 172 "MTUS1,KLHL13,GAS7,APOC2,DST,CD38,RCBTB2,TPP1,LY86,PLXNA4,EDNRA,RASGRP1,GALC,HPGDS,PRUNE2,HNMT,IGF1,TTYH2,LIG4,SCAMP5,ADAM22,LAYN,MYO7A,P2RY13,NCF2,NOVA1,P2RX7,SH3KBP1,PRKCB,GDPD1,SEC14L1,SLC11A1,CPEB4,RGL1,SYPL1,DMXL2,LRRC8A,NPL,P2RY12,ZFAND5,EVI5" Coexpression 18794137-SuppTable1b Human Breast_Creighton08_623genes GeneSigDB 1.88E-06 2.14E-02 1.14E-04 1.13E-03 76 398 "ABHD6,NME5,CC2D2A,SPOP,SHROOM2,CCDC74A,RNF182,ZNF599,CASTOR3,JAZF1,CAMK2G,SLC25A14,LRWD1,LHX2,CLTC,NGEF,HECTD1,IQCK,FAM149A,SLC4A8,TOGARAM2,ARHGEF4,GAPVD1,DNAL1,WDPCP,FSD1L,RAB9B,CDKL3,DNAJC27,CEP78,ZMYND10,SCARA3,IQCG,DCTN2,EFCAB2,POMT1,AK8,ABLIM2,KIAA1841,MSL3,FAM19A2,LINGO1,PSIP1,MAP6,EFHB,NPTX2,CEP41,TMEM231,CCDC40,REV3L,RFX2,RFX3,NEK11,RMI1,HES6,PPM1E,DZIP1,RADIL,IFT122,TMCC1,ZHX3,NEK4,RPGRIP1L,DNAH7,TMEM121,NACC2,ACTR6,CDK20,ZNF346,PPIL6,REEP1,EML6,DNALI1,MDH1B,ST7,NETO2" Coexpression M9910 Genes down-regulated in dendritic cells: untreated versus 8h after infection of Leishmania major. MSigDB C7: Immunologic Signatures (v6.0) 2.04E-06 2.32E-02 1.24E-04 1.23E-03 45 197 "MTUS1,ABCD2,ATP1A3,BMPR1B,DST,CACNA1G,IL33,HAP1,CAMK2G,SLC25A14,USP6,CLCN3,TPP1,SNCAIP,RGS17,GPHN,ZNF391,RRAGB,BAIAP2,PCYOX1,NBEA,GABRA3,GPR162,PCLO,MAPT,LRP1B,MEIS2,PCDHGC3,PFKFB4,CEP41,MAPK9,GRAMD1C,LAMA1,RGS3,TMLHE,RPE,FAM192A,FHOD3,PKNOX2,SYT1,HIF3A,CDK20,RUSC1,WNT7A,NAV3" Coexpression M6878 Genes down-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il. MSigDB C7: Immunologic Signatures (v6.0) 2.13E-06 2.41E-02 1.27E-04 1.26E-03 42 179 "AXIN2,SYT13,PITPNM2,SEMA7A,SFMBT2,ARRB2,BMP7,DST,METTL6,ZMYM4,MAGED1,CLOCK,LRIG1,FAM107B,RASGRP1,MBNL2,PTK2B,FGF13,EVL,FYN,RAPGEF6,NEU3,FUT10,AGFG1,IL6ST,JAK2,SLC35G1,HECTD2,KCTD6,SLC11A2,P2RX7,PLCL1,SH3KBP1,DRAM2,EPDR1,PTPN13,RFX3,DZIP1,SLA,USP33,DOCK9,TTC3" Coexpression M2520 Loci bound exclusively by SALL4 [GeneID=57167] isoform b in ES cells (embryonic stem). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.14E-06 2.43E-02 1.27E-04 1.26E-03 93 517 "MTUS1,SPARCL1,DPP10,MAP4K3,CASK,ASPA,PTCH2,ADAM23,BARD1,DST,CACNA2D1,CD38,DIS3L,CNOT8,CLCN3,ABCG2,PCYT1B,RCHY1,NCOR1,VCAN,SOCS5,PNPLA8,KIAA0408,HDAC9,TM9SF4,IST1,ELMO1,RUSC2,FAM107B,CPEB2,RCAN1,DNAJB6,FEM1B,PIPOX,TUBB3,UBE2E3,EFCAB2,UFM1,FUT9,GAD1,DBF4,SPIN1,CBX1,ADAP1,LPAR4,PCLO,ADAMTS6,PACSIN2,HLF,RBPJ,LRRCC1,KLHL23,KIT,IPO5,EFHB,MEIS1,MGAT3,NFE2L2,PAX6,PRIMPOL,DRAM2,PPP3CC,SLC25A36,RIC8B,SETD5,RPS20,RTN1,CSRNP3,TNFRSF19,ST8SIA1,ANKRD6,EPN2,CCDC88A,INAVA,KIF13A,SPP1,LMO3,PBLD,TROVE2,TCEA1,SLC19A3,OBSL1,ITGB3BP,TIMP4,CBX5,PARD3,ZFP37,ZNF708,ZNF189,UPF3A,RTN4,PHTF2,RNF146" Coexpression M18441 Genes down-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.14E-06 2.43E-02 1.27E-04 1.26E-03 52 241 "CDC42BPA,CDC14B,CFLAR,BMPR1B,ARHGEF7,SPAG9,SEPT7,FOXN3,QKI,MAP4K4,ARMC8,ARHGEF10,SEC14L5,DLC1,PDLIM5,NSG1,IP6K3,ZNF638,LAMA2,LSAMP,MAPT,NEK1,DPY19L2P2,SUSD4,ZNF493,RBBP6,SLC25A36,RORB,PCMTD2,ARMH4,ATF7IP,CPEB4,GKAP1,COA1,INAVA,SNRPN,FAM126B,PDZD2,ZBTB43,KANK1,TACC1,PCDHGA10,PCDHGA4,SYNE1,CA14,TTC3,ZNF189,SLC38A1,STOX2,SMIM8,DPF3,CPNE4" Coexpression 16273092-TableS1b Human InVitro_Bild06_298genes GeneSigDB 2.23E-06 2.53E-02 1.32E-04 1.31E-03 51 235 "HACE1,ADGRB2,DIS3L,B4GALT6,ABCG2,RAB26,LRIG1,TSPAN5,PCOLCE2,USPL1,ENO2,CEP78,FGFR3,CAMKK2,KHDRBS3,CSPG5,KDM2B,GNAL,TPPP,PSIP1,UBE2QL1,METTL21A,TM6SF1,KCTD6,TMOD2,PFKFB3,RETREG1,KCTD15,EPB41L4B,PTCH1,SCN8A,MRAS,SH3BGR,FERMT1,GKAP1,KDM4B,PEG10,CDK19,STXBP1,DNAJC9,SIN3B,TIAM1,HEY1,UGT8,LYPD6,REEP1,EML6,ZNF195,SLC30A4,PHTF2,NETO2" Coexpression 16014634-Table1 Mouse Brain_Hagemann05_93genes GeneSigDB 2.28E-06 2.59E-02 1.34E-04 1.33E-03 25 83 "ATP2A2,ATP2B2,CACNA1G,CSF1R,DLX1,ENO2,GAD1,CPLX1,GRIA2,GSN,ITGAM,MAPT,MEIS1,NEFM,NFE2L2,PAX6,PMP22,PTX3,STX1B,SLC8A1,SNAP25,SPP1,SYP,SYT1,VAV1" Coexpression M1410 Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [GeneID=4609]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.39E-06 2.72E-02 1.40E-04 1.39E-03 120 712 "ASPHD1,ACADM,ADCY8,OGT,PKP4,PARG,APAF1,GAS7,ARSE,EIF4G3,ATP2A2,BACH1,BCL7A,SGCE,LDLRAD4,CALM1,KALRN,CAST,CCK,KRIT1,CCNH,SLC16A4,UBE2L6,RCBTB2,SRSF11,SOCS6,RCHY1,NSL1,NECTIN3,AKAP12,LRIG1,CTH,ZFYVE16,YTHDC1,ELMO1,GSDME,DDX46,DOCK2,E2F5,EDIL3,RASGRP1,YAF2,PLXNC1,EIF5,USPL1,EIF1,SRRM1,VPS26C,ACSL4,TAOK3,SCML2,FDFT1,SEC24B,COPS8,GLUL,CBX1,LILRB4,PSIP1,NCKAP1L,ELOVL5,GABARAPL2,HMGCR,IFI16,IL6ST,KLHL23,KTN1,LAMP2,SMAD1,MBNL1,ADAM22,NFE2L2,CDK18,PPM1B,PPP3CA,PPP3CC,PRKACB,PRPH,PRPSAP2,SNRK,PTPN13,PTPRG,PEX2,RAD17,REV3L,RGS4,CLIP1,SCP2,TRA2B,RBM34,USP33,MYCBP2,CLASP2,NXT2,CEP68,PRRC2C,SYPL1,COBL,ANKRD28,FAM208A,FBXW11,TCEA1,DMXL2,TCF12,ITGB3BP,THRA,R3HDM1,TP53BP2,RUNDC3B,SSBP2,UBC,UBE3A,VLDLR,WNT7A,TRIM9,ZFAND5,EVI5,KCNAB1,MPPE1,RTN4,HNRNPA3" Coexpression 16318415-TableS1 Human Kidney_Zhao06_259genes GeneSigDB 2.41E-06 2.74E-02 1.41E-04 1.39E-03 49 223 "SYN3,MTUS1,CC2D2A,SEMA6A,LDB2,CD86,IQCK,NECTIN3,ANKRD44,PDE4DIP,ELMO1,RHOBTB1,EBF1,EDN1,EDNRB,TMTC1,OPTN,FAM13A,PCOLCE2,SH3YL1,FLT1,PPARGC1A,GRB10,FRMD3,HLF,ACOT7,SYNPO,L1CAM,LIFR,MEF2C,MID1,MYO9A,NPTX2,ENPP2,MASP1,SGK1,SYBU,PPP4R3A,ARHGAP26,RGL1,NSFL1C,PLCB1,TACC1,TCF4,SIK3,NPL,UBE3A,ZNF189,NHSL1" Coexpression 18032706-SuppTable3 Human Leukemia_Ruiz-Vela08_468genes GeneSigDB 2.43E-06 2.76E-02 1.41E-04 1.40E-03 74 387 "ACTN1,GALNT16,ADRB2,HACE1,LCORL,APBA2,APOC1,APOC2,CPNE5,SPTBN4,CADPS,ASGR1,ATP6V0A1,ST3GAL5,C5,TIGD7,RCBTB2,CHGB,RAB33A,HOMER3,PICK1,LETMD1,COL9A3,ANKRD44,PLCXD3,CTH,BOC,DBN1,GSDME,CD99L2,SHANK1,OPTN,APC2,REEP2,DLC1,ST3GAL6,SYNCRIP,TPK1,GAA,HIGD1B,TDRKH,MIER3,DISP2,ITGAM,LMO2,LSS,MAT2A,EFHB,TM6SF1,MX1,NPTX1,JAKMIP1,POLR2F,TATDN3,PRODH,PTPRH,RFX3,CARF,TCP11L1,RPS6KA2,SAFB,FHOD3,GKAP1,ARHGEF9,SIN3B,ZFP90,DNAH7,TST,VLDLR,ZNF70,POLR3H,NT5M,MDH1B,PCBP4" Coexpression M372 Genes down-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 2.45E-06 2.79E-02 1.42E-04 1.40E-03 38 156 "ACTN1,OGT,SFMBT2,ARRB1,INSYN2B,EIF4G3,ENTPD4,SOCS5,TBC1D5,ARMCX2,DOCK2,MBNL2,KMT5B,PLEKHA1,EVL,GABBR1,NEU3,BACH2,IL6ST,P2RX7,PTPN13,RIC8B,PCMTD2,CHD9,WDR37,ZKSCAN3,KIF13A,MYCBP2,SMG6,TCF12,SYNE1,NSD1,BHLHB9,SSBP2,RICTOR,KCNAB1,ST7,JMJD1C" Coexpression M14698 "Genes up-regulated in the common lymphoid progenitor (CLP, defined as CD34+CD38-CD7+ [GeneID=947;952;924]) compared to a multipotent cord blood cell (defined as CD34+CD38+CD7-)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-06 2.88E-02 1.45E-04 1.44E-03 27 94 "BTK,LRRFIP1,RBM39,NCOR2,OSBPL3,KMT5B,EVL,ADAM28,IRF8,MSL1,MN1,NACA,NF1,PRKCB,RBBP6,SETD5,BAALC,RPS6KA2,STK32B,SATB1,SLC2A5,SMARCA4,KDM3A,COBL,TCF4,METTL3,SLC38A1" Coexpression M1741 Genes whose promoters are bound by FOXP3 [GeneID=50943] based an a ChIP-chip analysis. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-06 2.89E-02 1.45E-04 1.44E-03 89 491 "ESYT2,BEND6,ZNF608,WDR35,OSBPL8,CC2D2A,AMPH,CADPS,ATP1B3,SGCE,LDLRAD4,CACNB4,CAST,RCBTB2,MS4A7,EPS15L1,HECTD1,MAP4K4,CREM,ANKRD44,LRIG1,ARHGEF10,USP6NL,TBC1D5,ELMO1,FAM107B,USP3,E2F6,EPB41,ENPP6,GPHN,PTK2B,FYB1,FYN,GABRG1,RAPGEF6,SESN1,GGTA1P,MALT1,GPD2,ADAMTS6,ICA1,IL6ST,FAM69A,MBNL1,NINJ2,PDE4B,GNG2,PIK3R1,SH3KBP1,PPP3CC,CEP97,ENOX1,RBBP6,GTDC1,RFX3,GLDN,SATB1,ATXN7,SCN8A,TRA2B,RASA3,FERMT1,ST6GAL1,ST8SIA1,WDR37,INTS9,SNCA,KDM3A,SPP1,CDK19,SAMSN1,SYNE2,ANKRD28,TCF12,GPRIN3,SIK3,KAT6B,UBE2H,TBC1D15,WIPF1,EVI5,URM1,PPP1R3F,PARP11,PHTF2,JMJD1C,ZDHHC20,SNX14" Coexpression M8036 Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus CD8 T cells stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 2.73E-06 3.10E-02 1.52E-04 1.51E-03 45 199 "ABR,ACTN1,NDRG3,BIN1,ARNTL,MARCH3,N4BP2L1,ADAM23,RAB29,CAST,CACNA2D2,CNOT8,RCHY1,COX4I1,AHCTF1,BAG4,GPRASP1,ZFYVE16,SPOCK2,PLEKHA1,RASGRP2,RABEPK,DENND4A,FCGRT,TRMO,TPK1,ZNF234,ZNF274,PRRC2B,BTN2A1,BACH2,HSPA1L,ICA1,IL6ST,N6AMT1,FBXO11,WDR37,ZSWIM8,SAMSN1,PRRC2C,AGTPBP1,TBL1X,TBC1D15,MPPE1,JMJD1C" Coexpression M6443 Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B2 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.73E-06 3.10E-02 1.52E-04 1.51E-03 45 199 "AMPD3,MADD,TMEM108,STX16,KRIT1,SCARB1,ENTPD6,ARMC8,NCOR1,UBXN2A,RIPOR2,EBF1,ERBB4,EVL,RAPGEF6,IQGAP2,CNTRL,PADI2,L1CAM,MARK3,MYO9A,PALM,SERPINI1,PURG,PRIMPOL,TATDN3,SNRK,RBBP8,CCDC25,PCMTD2,SEMA6D,RASA3,PPP4R3A,CCDC88A,ZKSCAN3,TMCC1,DOP1A,TMEM150C,ANKRD12,MLST8,SZT2,RICTOR,AMZ1,TMEM178A,JMJD1C" Coexpression M3104 Genes up-regulated in comparison of naive T cells versus effector memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.73E-06 3.10E-02 1.52E-04 1.51E-03 45 199 "ACTN1,ELFN2,KLHL13,PITPNM2,APBA2,SFMBT2,DDR1,KYAT1,SCARB1,NOG,IPCEF1,GPRASP1,SNPH,ARMCX2,KLHL3,SLC12A6,SCML2,FCGRT,NBEA,RAPGEF6,GGT7,ADGRA3,ZNF496,LINC01089,LINC01550,BACH2,IL6ST,KPNA5,DNHD1,NUCB2,PCSK5,LRRN3,CEP41,TUG1,BEND5,GAL3ST4,SATB1,CNKSR2,TBL1X,PRRT1,TOM1L2,ZNF708,ZNF138,AMN1,KLHDC1" Coexpression M10091 Genes down-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.73E-06 3.10E-02 1.52E-04 1.51E-03 45 199 "TAOK1,GPRASP2,EPB41L5,DOCK11,SPAG9,RUNX1T1,LONRF2,CFL2,SLIT2,RCHY1,PREPL,SOCS5,GPRASP1,HDAC4,SPOCK2,GSDME,CDON,EXTL2,ARMCX1,FER,FGF13,FLNC,FERMT2,PSIP1,IFI16,KPNA5,NELL2,PMP22,PPP2R5E,ACSS3,ZNF532,PNMA8A,DOK5,RGL1,TCF4,ZFPM2,TIAM1,BEX4,FLRT2,XPO1,REEP1,TMEM237,SLC30A4,PLSCR4,RNF146" Coexpression M7978 Genes up-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468]. MSigDB C7: Immunologic Signatures (v6.0) 2.73E-06 3.10E-02 1.52E-04 1.51E-03 45 199 "NCKAP5,ADRB2,MTUS1,TBC1D14,CHID1,DST,DDR1,CLTC,ABCG2,CNRIP1,CRYBB1,RUBCN,DMD,PLEKHA1,EPB41L2,ZNF585B,FCGRT,ANKFY1,FOLR2,RAPGEF6,SESN1,GGTA1P,HPGDS,SPIN1,GPR34,VSIG4,USP51,ICA1,IGF1,HECTD2,GPR155,SCAMP5,NBL1,RASGRF1,ZDHHC14,GAL3ST4,LGI2,SEC14L1,ST6GAL1,BTBD7,USP33,IQCE,ATMIN,UBE2H,ITM2C" Coexpression M17454 Genes up-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.03E-06 3.44E-02 1.68E-04 1.66E-03 101 578 "MTA3,MTUS1,ALCAM,BCAS1,CDC14B,SFMBT2,ARNTL,ARRB1,NCOA1,RASL11B,DOCK11,SYNJ1,PRMT9,DDR1,CAMK2G,CAST,CBR1,CCPG1,CFL2,B4GALT6,CLCN3,QKI,FAM149A,FAM171B,CRYM,CSNK1E,MFAP3L,WDR20,SEC16A,DLX1,RCAN1,ABCC5,GOLT1B,EBF1,EDN1,FAM13A,VPS13B,EPB41L2,ERBB2,ERBB4,DENND4A,FAM198B,RPS6KC1,FECH,FGF13,BAIAP2,SCARA3,JKAMP,FUT9,IQGAP2,TMEM8B,FERMT2,LNX1,DIDO1,GRIN2D,ZHX1,ICA1,INPP1,FAM69A,MARK1,MATN3,PPM1L,IDNK,NFIX,NPR2,SLC11A2,NUCB2,ZNF827,PDE4D,PDPK1,SMIM7,PMP22,PSAT1,SCHIP1,EPB41L4B,PKIA,PRODH,PTPN13,RIPOR1,C12orf49,DGLUCY,GALNT10,SLC12A2,LIMCH1,PDZD2,KANK1,KLHL7,TACC1,IQCE,AKTIP,BEX4,RPRM,TBC1D15,RICTOR,ZNF70,PRTFDC1,RNF103,FAM219B,TRAM2-AS1,GAN,SPATA13" Coexpression M17915 "Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.14E-06 3.57E-02 1.69E-04 1.68E-03 129 782 "RALGAPA1,BRAP,HACE1,OGT,CDC42BPA,GAS7,USP37,NCOA1,NUMB,STX16,KSR1,SYNJ1,ARHGEF7,SCAPER,CAST,CARS,CBS,TIGD7,CCPG1,UBE2L6,NPIPA1,RCBTB2,C4orf33,LETMD1,ENTPD4,RBM39,DZIP3,PNPLA8,CTH,CYBB,HDAC9,DBN1,USP3,CPEB2,SLC12A6,DPYSL2,ARRDC4,KLHL5,FSD1L,MBNL2,LINC-PINT,EIF5,IRAK4,PLEKHA1,ING4,EIF1,RPS6KC1,SH3YL1,PTK2B,PRAM1,GORAB,TPK1,OGA,FYN,ZNF274,ERAP1,MTHFD2,INPP5K,KIAA1841,GPT2,GRB10,SPACA9,PSIP1,MGC16275,MIER3,HMGCL,AGFG1,IFI16,INPP1,ITPKB,MIA2,MYO5A,ZNF862,NEK1,ALDH1L2,OGG1,PDE4D,PKD1,RETREG1,SMOX,PRIMPOL,PSAT1,POLG,MINDY2,TATDN3,PTPRE,TUG1,PPP2R3C,CEP97,RAD51D,RET,RFX3,SLC25A36,ZNF671,ADAL,TCP11L1,CLIP1,SARS,SEC14L1,SH3BP2,SHMT2,CCDC92,SLA,ARHGEF40,CPEB4,GKAP1,UHRF1BP1L,CDK19,ZNF621,ZSCAN29,TTBK2,ARHGEF9,MLST8,TBL1X,TCF4,TCF12,ARHGAP9,AKTIP,CBX5,SSBP2,UBE2H,FLRT2,VLDLR,PCBP1-AS1,EMSY,TUBA1A,VPS35L,NHSL1,RNF146" Coexpression M8110 Genes down-regulated in unstimulated macrophages: IL10 [GeneID=3586] knockout versus NFKB1 [GeneID=4790] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-06 3.57E-02 1.69E-04 1.68E-03 45 200 "VWA5B2,MADD,NCOA1,DPY19L3,KIF1A,LARGE1,NGEF,MAGED1,ZNF385A,SH2B1,LONRF1,PITPNC1,ZNF804A,EBF1,DCTN4,ERBB4,MRVI1,UFM1,FAM49B,SARAF,GAD1,KCNMB4,CACFD1,TOX2,L1CAM,LAMP2,SYTL4,IGSF11,PIK3R1,SMOX,LRP12,TMEM104,SGK1,WDR37,RADIL,BTBD7,CPEB4,GKAP1,KDM3A,TBCEL,USP22,AKTIP,PIK3R5,ELFN1,NLRP3" Coexpression M9186 Genes up-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-06 3.57E-02 1.69E-04 1.68E-03 45 200 "KCNH8,ASPHD1,ADD1,NME5,CALB1,HAP1,CAMK2B,KRIT1,FAM189A2,CNTNAP2,SNPH,DNAL1,TMCC2,RPS6KL1,DPP6,ABCC5,EIF4G2,GABRA3,TCERG1,PRUNE2,INPP5B,KCNN1,KTN1,MATN2,TAGLN3,PNMA3,PPM1B,PPP2R2B,CNTLN,PTPRG,MEG3,FOXRED1,MRAS,ZNF423,SSPO,ST5,STAC2,SYT1,MTCL1,TTC3,OSBP2,TSPAN11,ZFP37,PARP11,NETO1" Coexpression M5577 Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-06 3.57E-02 1.69E-04 1.68E-03 45 200 "NDRG2,C1QTNF3,AMPD2,BIN1,ALDH7A1,N4BP2L1,DCLK1,CDC42BPB,DCAF8,ZNF337,HS3ST2,EEF1D,PLXNC1,IRAK4,F8,FOXO3,SRCAP,TDRKH,SPACA9,BTN2A1,BACH2,IL6R,KCNN3,KIF5A,L1CAM,ZNF862,SMIM7,PRKACB,ACSS3,MORC4,ZNF532,SCN8A,ST8SIA1,IFT122,MYO16,DOP1A,TSNAXIP1,LHPP,FAM208A,PDLIM2,ZSCAN26,ANKS1B,SLC30A3,MARCH8,HNRNPA3" Coexpression M7500 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) versus non-Tfh. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-06 3.57E-02 1.69E-04 1.68E-03 45 200 "SYN3,SORCS2,WDR35,CEP126,ARHGDIG,INSYN2B,CLDN10,RAB33A,BAG4,RNF14,OSBPL3,FAM169A,LONRF1,PITPNC1,SNX29,KMT5B,TMEM35A,SH3YL1,OGA,FYB1,TRAF3IP2,SRCAP,LMO2,SHC3,SFR1,FAM184A,REV3L,CCDC25,PPM1E,KIF16B,MTERF2,ATF7IP,SPATA7,VPS13A,ANKRD12,SYNE1,FRYL,PRRT1,TNS1,TP53BP2,CDK20,MKRN3,ACTR3B,JMJD1C,ST8SIA2" Coexpression M2921 Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Brazil). MSigDB C7: Immunologic Signatures (v6.0) 3.15E-06 3.57E-02 1.69E-04 1.68E-03 45 200 "RNF157,UNC5A,SEMA6A,BBOX1,PDZD4,ANK2,VAT1L,ZFYVE28,DNAH17,CALB1,ARHGEF6,SLC35F1,PPP6R2,ARMCX2,FARSB,EDNRB,CALCRL,ERBB2,TPPP3,GGT5,ATOH8,AGFG1,ASPRV1,CHIC1,TM6SF1,NFE2L2,NOVA1,CYTL1,PDZRN4,MINDY2,PPP1R1A,PRKAB2,CEP97,ATP8B4,SATB1,FAM102A,DZIP1,SLC4A3,BTBD3,SLC6A11,ZBTB43,DDN,STAU1,MGRN1,ZIC2" Coexpression M12763 "Genes depleted in embryonic, neural and hematopoietic stem cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.17E-06 3.60E-02 1.70E-04 1.68E-03 23 74 "ABR,AP2A2,BIN1,KCNAB2,GAS7,LY86,COL11A2,CSF1R,CST3,ST3GAL6,EVL,B4GALNT1,GRIA2,GSN,STMN1,PPP3CA,PRKCB,RELN,ROGDI,ZDHHC14,SLC11A1,LAT2,PLD4" Coexpression M19508 Genes with hypermethylated DNA in lung cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.25E-06 3.70E-02 1.74E-04 1.72E-03 74 390 "C1QTNF1,BEGAIN,AMT,ANK2,MAP4K3,CADPS,PDE8B,ATP2A2,PROM1,LDLRAD4,CFAP410,RGN,ARHGEF1,SYNGR3,CACNA2D2,ARHGAP22,SLIT2,GAL3ST1,SEC31B,CSF1,LRIG1,LRRC3B,PDE4DIP,PYGO1,SPOCK2,DTNB,CNNM1,RASGRP1,RASGRP2,SH3YL1,DLC1,FECH,OLFM1,FGF11,ST6GALNAC3,TPPP3,GALNT15,FAM107A,SOWAHA,ITPKB,KIT,NEFM,NFIX,NME4,ENPP2,RETREG1,PLCB2,PLTP,NKAIN4,ZIK1,RBBP6,HKR1,MRAP2,ZNF671,STK32B,RYR3,LRFN5,LHPP,SULF2,NECAB1,ADAMTS17,TACR1,EXOC7,PCDHGB2,VWCE,CSMD1,PIK3R5,ZNF154,ZNF177,ANKS1B,SPIRE1,MEIS3,STOX2,PRDM8" Coexpression 18757322-TableS3 Human Breast_Creighton08_584genes GeneSigDB 3.29E-06 3.74E-02 1.75E-04 1.73E-03 87 480 "MTUS1,OSBPL1A,NME5,PKP4,APAF1,APBB2,ZBTB10,ALDH7A1,N4BP2L1,RAB29,CAMK2G,CAST,LARGE1,RCBTB2,FOXN3,CNOT8,TPP1,QKI,LETMD1,COL9A3,LRIG1,DZIP3,ARHGAP32,TBC1D5,RHOBTB1,FRY,OPTN,ING4,ERBB4,RRAGB,GMPR2,ARMCX1,SH3YL1,CHST15,FGF13,FHL1,IP6K2,TPK1,GALC,INPP5K,BRD8,GLUL,RAB40B,STON1,GABARAPL2,HMGCL,HNMT,IL6ST,KCNN2,LMO2,MATN2,MXI1,NELL2,SNX10,RETREG1,PLCL1,PMP22,RETREG2,DIRAS2,PTCH1,ELOVL2,PTPN13,ACSS3,EXD2,PCMTD2,NEK11,LMBRD1,SOX3,SPATA7,KDM3A,GLT8D1,CDK19,ZNF302,CEP68,TACC1,TRIM2,SIRT1,BEX4,SGK3,TBC1D15,WIPF1,ZNF32,RNF103,PLSCR4,MARCH8,UBE3B,FXR1" Coexpression M1810 Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.37E-06 3.82E-02 1.78E-04 1.76E-03 37 152 "MTUS1,SPOP,BCL7A,ARHGEF7,USP6,QKI,DOCK4,E2F5,VPS13B,SUCO,FOXO3,FYN,ZNF638,FERMT2,RBPJ,KIF2A,MEIS1,MN1,CNOT4,PTK2,REV3L,SLC25A36,CHD9,FNDC3A,DOP1A,PRRC2C,MTCL1,CLASP1,DOCK9,FRYL,KAT6B,SSBP2,FLRT2,VLDLR,XPO1,NAV3,KAT6A" Coexpression M17183 Set 'Oct4 targets': genes upregulated and identified by ChIP on chip as OCT4 [GeneID=5460] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.40E-06 3.87E-02 1.79E-04 1.77E-03 59 290 "PARG,CDC14B,BMP7,CA4,CACNA2D1,SPAG9,LARGE1,PLAA,IST1,TMEM170A,MYEF2,WDR20,MED12,DPYSL2,DTNA,AASDH,KLHL5,PIPOX,FGFR1,APOPT1,UFM1,OGA,TNRC6A,KCNMB4,STMN2,FICD,LINGO1,HAS2,IFI16,KCNN2,MEIS2,NEFM,ENPP2,ANKHD1,RASGRF2,RIC8B,SALL1,SNRPN,KDM3A,LHPP,KANK1,DNAJC9,TAL1,FBXW11,KLHL4,TCF4,TCF12,OBSL1,SLC44A1,PARD3,CHST5,TRPS1,SSBP2,ZKSCAN5,ZIC1,ZIC2,SMARCAD1,URM1,KAT6A" Coexpression 18614019-TableS4d Mouse StemCell_Fazzio08_1078genes GeneSigDB 3.59E-06 4.08E-02 1.88E-04 1.86E-03 110 645 "AXIN2,ALCAM,SEMA7A,VAT1L,CPNE5,MARCH3,NCOA1,KSR1,DST,CALB1,SLC25A14,CAPN3,CH25H,CBLN1,RGN,EVI5L,DLGAP1,CCPG1,SLIT2,VAX2,CRYM,PHACTR3,CNTNAP2,CYBB,BRINP1,C2CD2L,FAM107B,DYNC1I1,ECM2,FEM1B,EEF1D,AASS,PCOLCE2,LRRC17,TUBB3,SCML2,FCGRT,FGF1,BAIAP2,HPCAL4,ATP13A4,TMEM175,TPPP3,ZMAT1,DISC1,ACSS1,GLUL,GPD1,PCLO,FICD,NCKAP1L,GABARAPL2,HP,MYLK2,KCNN2,ASPRV1,EFHB,MEIS2,NINJ2,NPY,NPTX2,TREM2,PCDH8,PCDH9,PLCD1,MAGEL2,SH3KBP1,NKAIN4,RASGEF1B,SKOR1,RELN,PTPN13,PTPRE,PTPRO,TMEM231,MARCH1,ZCWPW1,CRTAC1,ROBO1,RXRA,RYR3,CSRNP3,SMPD3,HKDC1,PREX2,SLC6A8,SLC11A1,EPC1,LIMCH1,ZHX3,LHPP,THSD1,APOM,RHBDL3,ADGRL3,DOCK9,SLC19A3,ZNF106,RIMBP2,TNS1,NPL,IL34,DCBLD1,VAV1,AMZ1,EPM2A,TMEM63C,NETO2,DPF3,CPNE4" Coexpression M8394 Genes up-regulated in dendritic cells: spleen CD8- versus brain. MSigDB C7: Immunologic Signatures (v6.0) 3.72E-06 4.23E-02 1.94E-04 1.92E-03 44 195 "ADORA1,ADRA1B,ADRB2,AGT,ABCD2,SHROOM2,SLC4A4,MYOM1,KSR1,SULT4A1,COL4A5,RGS6,DNAH9,REEP2,GPER1,KCNJ5,KIF5A,L1CAM,MAN2A2,MAP2,ADAM22,SAMD14,NOVA1,PLCB2,SCHIP1,POLR2F,PTPRD,RGS4,S100B,SCN7A,SLC12A4,MAST1,MAPKBP1,DDN,PLCB1,SYN1,ASTN2,IQCE,SMG6,SZT2,THRA,CDK20,ZIC1,SLC30A3" Coexpression M8234 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype vs RORC [GeneID=6097] knockout treated with digoxin [PubChem=2724385]. MSigDB C7: Immunologic Signatures (v6.0) 3.98E-06 4.52E-02 2.06E-04 2.05E-03 40 171 "PDZD4,USP37,CDC14B,SEMA4G,GPR146,CFLAR,PHF14,CNNM1,CORO2B,SLC37A3,CHL1,RAPGEF6,IQGAP2,MALT1,GSN,TOX2,IRF8,ITGAM,KTN1,STMN1,GPR155,PPM1L,P2RX7,PKM,JAKMIP1,SH3KBP1,TMEM231,CLIP1,FAM102A,PPM1E,SHC4,ST6GAL1,ST8SIA1,SLA,UHRF1BP1L,ARHGAP26,RPGRIP1L,TRIO,MAP3K12,JMJD1C" Coexpression M11011 Genes down-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.00E-06 4.54E-02 2.06E-04 2.05E-03 38 159 "BIN1,APLP1,ASPA,LINC00847,SYNJ2,MTMR2,MYRF,CAPN3,ARHGEF2,COL4A5,ARHGEF10,SPOCK3,SRPK3,ABCA8,PTK2B,FOLH1,GPR37,LAMP2,MAPT,SCAMP5,MX1,NTRK2,P2RX7,CDK18,ENPP2,PIK3R1,PMP22,KLK6,RASGRF1,RDX,RNASE1,NFASC,SS18,DICER1,TIAM1,TRIO,UGT8,CLDND1" Coexpression M1920 Genes forming the macrophage-enriched metabolic network (MEMN) claimed to have a causal relationship with the metabolic syndrom traits. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.25E-06 4.82E-02 2.17E-04 2.16E-03 185 1210 "ABR,NDRG2,ADCY6,PTCHD1,OSBPL8,SRPX,TRMT9B,FAM131A,ARHGDIA,ARRB2,ASGR1,DYNLL1,ATP1A3,ATP6V0A1,DOCK11,BACH1,BCS1L,NRP2,SYNJ1,RAB29,WASF1,IL33,CH25H,KYAT1,CERS5,CD86,CD38,ENTPD2,LARGE1,NUMBL,MS4A7,B4GALT6,ARHGAP22,LY86,HOMER3,GAL3ST1,TBPL1,ZNF521,CNRIP1,ABCG1,CSF1R,CSF2RA,LRIG1,OSBPL3,VCAN,FAM131B,CYBB,MYADM,ARMCX2,HEPH,SHANK1,DOCK2,TOM1,ABCC5,EBI3,PLXNC1,RASA4,CERCAM,EPB41,EPB41L2,IGSF6,SPEG,TLR7,FAM198B,RPS6KC1,TBC1D16,PTK2B,TAOK3,FCGR1A,FCGR3A,TMEM164,FHL1,EVL,SEMA4D,ANKFY1,HVCN1,AK8,FAM49B,SDCBP2,IQGAP2,MTHFD2,ACSS1,GATM,SESN1,GGT5,HPGDS,STARD3,SPACA9,GSN,SLC2A6,RASSF8,PADI2,NCKAP1L,SYNPO,ICA1,IRF8,IFI16,LRRC25,KCNN2,STXBP5,L1CAM,LAMA2,LAMP2,LMO2,PIK3AP1,MAP4,MATN2,TM6SF1,PPM1L,MSR1,NRBP2,LAYN,MYO5A,TCEAL5,P2RY13,NCF2,NFE2L2,SLC11A2,TREM2,CDK18,PKM,FAM216A,SMOX,SLC25A23,PLTP,PMP22,LRP12,PILRA,RASGEF1B,MAPK7,PRODH,GDPD1,PSD,CYBC1,SPDL1,PTPN13,PTPRE,PTPRO,RIPOR1,C1orf54,SUSD4,KCTD17,SLC25A36,RNH1,LGI2,MCMBP,RPS6KA2,PTGR2,SEMA6D,RASA3,SH3BP2,SYBU,SLC4A3,SLC6A8,SLC8A1,SLC11A1,TRERF1,UNC5B,SPTAN1,ITPRID2,SAMSN1,SSTR2,RGL1,PHLDB1,STXBP1,NECAB1,SYP,SLC37A2,ZFP90,TPCN2,OBSL1,ARHGAP9,HEY1,TLR4,NPL,BCL2L13,VAV1,LAT2,NPDC1,AMZ1,SEMA3B,ITM2C,PLD4,DOCK8,FRMD6" Coexpression M8513 Genes up-regulated in the normal-like subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.26E-06 4.84E-02 2.17E-04 2.16E-03 86 476 "ADGRF5,SPARCL1,SRPX,BBOX1,BIN1,ANK2,DST,BTK,IL33,CH25H,RUNX1T1,CD38,CDO1,FOXN3,CRY2,SNCAIP,CSF2RA,PPP1R16B,RIPOR2,GIT2,ELMO1,CHRDL1,DMD,DOCK2,DTNB,EDN3,RASA4,AASS,RASGRP2,EZH1,ABCA8,FHL1,FOLR2,NSG1,FYB1,FYN,CHL1,ADAM28,GGT5,LYVE1,FAM107A,IRF8,IFI16,IGF1,IL6R,ITGA7,KIT,LAMA2,PACRG,MATK,MATN2,MBP,MEF2C,MGAT3,MT1M,NPR2,NTRK2,OXTR,PCSK5,ENPP2,CYTL1,PIK3R1,PLCB2,FXYD1,PLTP,POU6F1,LRRN3,PPP3CC,PRKCB,RELN,PTN,CCDC102B,BAALC,S100B,SATB1,ST6GAL1,SLA,CCDC88A,SLC12A4,TCF4,ZEB1,SYNE1,FLRT2,WIPF1,ITM2C,NLRP3" Coexpression 19185848-TableS4 Mouse StemCell_Read09_300genes GeneSigDB 4.27E-06 4.85E-02 2.17E-04 2.16E-03 48 221 "APC,PPFIA3,SEMA4G,MADD,ARHGEF7,CACNB4,EVI5L,LRWD1,CHGB,RNF14,SCRN1,PLEKHA1,APC2,CINP,GABBR1,GPR162,UBE2QL1,L1CAM,MAPT,POC1B,PLCD1,SH3KBP1,MINDY2,PKIA,MAPK10,RIPOR1,RTN1,STX1B,PPM1E,WDR47,CPEB4,EPC1,ZBTB43,NFASC,STXBP1,SYN1,SYT1,TCF4,GPRIN3,TRIO,TTC3,SLC35A4,NDRG4,REEP1,MAP3K12,GDPD5,NELFE,NETO2" Coexpression 15869706-Table3 Human Cervical_Rosty05_51genes GeneSigDB 4.40E-06 5.00E-02 2.23E-04 2.21E-03 17 46 "PPFIA4,DDO,CAMK2B,NRN1,FGFR3,GNAO1,GRIK4,NEFH,ANKRD6,SLC4A3,SLC6A8,SMARCA4,OGDHL,ADGRL3,TRIM2,KCNE5,ZXDA" Coexpression 18223198-Table3 Human Brain_Chen-Plotkin08_40genes_FTLD-U GeneSigDB 4.64E-06 5.27E-02 2.34E-04 2.32E-03 14 33 "DLGAP2,COL4A5,HS3ST2,ECM2,EGR3,NRN1,ABCA8,GFRA2,NPTX2,PTPRN,SLC14A1,ARC,SYT5,VGF" Coexpression 18849563-SuppTable3a Human Lung_not_cancer_Bhattacharya09_220genes_FEV1inCOPD GeneSigDB 4.67E-06 5.30E-02 2.34E-04 2.32E-03 37 154 "ABHD6,CEP126,LTBP4,APBB2,RUNX1T1,CBLN1,LETMD1,DLC1,ATP13A4,ZNF44,LRP1B,KITLG,MITF,MYT1,PRTG,PPP3CC,GDPD1,PTCH1,RBBP6,GSTCD,ROBO1,SEMA6D,SH3GL3,ANKRD6,SLC2A5,SEPHS1,MTERF2,GKAP1,ZNF302,TMEM150C,KHDC1,UBTF,PLEKHH2,ZNF23,ZNF177,DNAH10,ZNF30" Coexpression 18849563-SuppTable3b Human Lung_not_cancer_Bhattacharya09_220genes_FEV1/FVCinCOPD GeneSigDB 4.67E-06 5.30E-02 2.34E-04 2.32E-03 37 154 "ABHD6,CEP126,LTBP4,APBB2,RUNX1T1,CBLN1,LETMD1,DLC1,ATP13A4,ZNF44,LRP1B,KITLG,MITF,MYT1,PRTG,PPP3CC,GDPD1,PTCH1,RBBP6,GSTCD,ROBO1,SEMA6D,SH3GL3,ANKRD6,SLC2A5,SEPHS1,MTERF2,GKAP1,ZNF302,TMEM150C,KHDC1,UBTF,PLEKHH2,ZNF23,ZNF177,DNAH10,ZNF30" Coexpression M7514 Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.77E-06 5.41E-02 2.37E-04 2.35E-03 74 394 "ACADM,NDRG3,OSBPL1A,TXNDC16,SPARCL1,LTBP4,CASK,ATP6V0A1,ADAM23,ST3GAL5,CACNA1G,CACNA1A,ARHGEF25,LRBA,CDO1,TPP1,CNN3,COL4A5,MAGED1,AKAP12,DCAF8,DNM1,TOM1,EBF1,RASA4,MTSS1L,FGFR1,DCTN2,ERGIC3,OGA,GAA,SESN1,GHR,GRB10,GSN,ZHX1,SYNPO,IL6ST,LAMA2,LAMP2,LSS,MATN2,MEIS1,PTOV1,NRBP2,NFIX,NUCB2,PIK3R1,PLCD1,PLTP,PMP22,POU6F1,PPP3CA,PTPN13,PTX3,MEG3,SCP2,HES6,SEC31A,SIRT2,SLC12A2,SPTAN1,TCF4,ZFP90,USP22,THRA,NACC2,TRIO,SSBP2,TTC3,UBE2H,ZNF32,MEIS3,ITM2C" Coexpression M19488 "Genes up-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [GeneID=9260], a latent gene of Epstein-Barr virus (EBV)." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.88E-06 5.54E-02 2.42E-04 2.40E-03 76 408 "CLK4,FMNL2,KLHL13,ALCAM,CDC42BPA,PKP4,USP37,CADPS,ZBTB10,ARHGEF7,CALB1,SPAG9,B4GALT6,CNR1,FAM171B,RBM39,SNCAIP,PHACTR3,APPL1,RIMS2,MATR3,ZNF804A,HEPH,DMD,DYNC1I1,NR1D2,TMTC1,MBNL2,EIF4G1,F5,SYNCRIP,MEGF10,MTHFD2,GATM,GHR,SPIN1,IRAK3,HNMT,ZNF678,KIT,LIFR,LIMS1,MATN2,MBNL1,MEST,MYO6,ENPP2,FAM98B,OLA1,SERPINI1,LRP12,ING3,PTPN13,PTX3,OXR1,RET,SLC25A36,RPE,FBXW7,TNFRSF19,HSPA4L,SYBU,SLC12A2,CPEB4,ANKRD36,FAM126B,ANKRD12,TCF4,TRIM2,ZMAT3,SSBP2,TTC3,UGT8,USP1,PRTFDC1,NETO2" Coexpression M3062 The 'group 2 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.06E-06 5.75E-02 2.50E-04 2.48E-03 85 471 "ABHD6,PSMG3-AS1,NME5,CC2D2A,SPOP,SHROOM2,RNF182,ZNF599,CASTOR3,JAZF1,SLC25A14,LOC730101,LRWD1,LHX2,NGEF,HECTD1,IQCK,FAM149A,SLC4A8,TOGARAM2,ARHGEF4,GAPVD1,DNAL1,WDPCP,FSD1L,PLXNC1,RAB9B,CDKL3,DNAJC27,CEP78,ZMYND10,SCARA3,IQCG,DCTN2,EFCAB2,POMT1,AK8,TPPP3,ABLIM2,KIAA1841,MSL3,CNTRL,SPACA9,FAM19A2,LINGO1,PSIP1,CFAP126,MAP6,EFHB,NPTX2,DPY19L2P2,CEP41,TMEM231,CCDC40,REV3L,RFX2,RFX3,NEK11,MELTF-AS1,RMI1,HES6,PPM1E,DZIP1,RADIL,IFT122,CABCOCO1,TMCC1,ZHX3,NEK4,RPGRIP1L,CCDC173,DNAH7,TMEM121,NACC2,CDK20,ZNF346,PPIL6,CLHC1,CFAP298,REEP1,EML6,DNALI1,MDH1B,ST7,NETO2" Coexpression M16859 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.22E-06 5.93E-02 2.57E-04 2.55E-03 94 535 "ELFN2,OLMALINC,KIAA1324,ALCAM,MARCH4,PKP4,NCOA1,ADGRB2,BARD1,RGS9,HIP1R,CBS,SEPT7,ZMYM4,DIS3L,CFL2,TBPL1,NCOR2,CTH,RIMS2,TCAF1,AIF1L,GUCD1,DNM1,CD99L2,DTNA,EDN1,FEM1B,EBI3,RASA4,DCTN4,MFSD10,MTSS1L,FGF1,FGF11,SCARA3,EFCAB2,UFM1,GABRB3,ZNF559,GCNT2,TOX3,PCLO,SYNPO,SCIN,MATN2,MITF,MN1,MOV10,NME4,ENPP2,SLC25A23,PSAT1,DRAM2,CEP41,PEX2,TUG1,TMEM255A,FIGN,TCP11L1,ST6GALNAC6,SARS,CASC3,GALNT10,EPN2,SEPHS1,SMARCC2,OGDHL,LIMCH1,SNCA,TMCC1,TEX2,CDK19,NFASC,PDLIM2,ATMIN,TCF4,KIAA0930,SYNE1,OBSL1,ITGB3BP,NACC2,PARD3,TNS1,TPM1,TRO,MGAT5B,VGF,LAT2,XRCC4,ZNF70,GDPD5,SEMA3B,MARCH8" Coexpression 15888489-Table1 Mouse Brain_Chung05_134genes GeneSigDB 5.43E-06 6.17E-02 2.66E-04 2.64E-03 28 103 "ALCAM,DOC2A,NRP2,BAIAP3,CALB1,CALB2,CBLN1,CCK,CDH2,NECTIN3,BRINP1,GSDME,PLXNC1,TENM1,FGF1,FGFR3,MPP6,GAD1,GHR,GRIN2C,IGF1,NEFM,RASGRF1,RNASEL,SATB1,SPP1,RPRM,KCNAB1" Coexpression M2440 "Genes up-regulated during neuronal differentiation of SH-SY5Y cells (neuroblastoma) in response to stimulation by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] and BDNF [GeneID=627]." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.50E-06 6.25E-02 2.68E-04 2.66E-03 10 18 "ASIC1,ANK2,SYNGR3,CNR1,SNCAIP,GABBR1,KCNB1,KCND1,SYT5,KCNAB1" Coexpression M7666 Genes up-regulated in ex vivo follicular dendritic cells: peripheral lymph node versus Peyers patch. MSigDB C7: Immunologic Signatures (v6.0) 5.66E-06 6.43E-02 2.74E-04 2.71E-03 44 198 "OGT,ASGR1,ADGRB3,CAPN3,SEC31B,AATK,FAM131B,DCAF8,HDAC4,SV2B,DOCK2,SUGP2,MBNL2,EZH1,SH3YL1,ZMYND10,FGF13,TRIM16,SARAF,DOT1L,SEPT9,GFRA2,LUZP2,HSPA1L,ADAM22,NOVA1,PIK3C2A,PLCD1,PPP3CA,PRKAB2,PRODH,MEG3,SEC31A,ZHX3,PEG10,ZC3H4,TAL1,SYNE1,TEK,NACC2,TSN,TTC3,INTS3,MPPE1" Coexpression M7672 Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]. MSigDB C7: Immunologic Signatures (v6.0) 5.66E-06 6.43E-02 2.74E-04 2.71E-03 44 198 "SPARCL1,OGT,CASK,PCDHGB4,RHBDL1,ENTPD2,CBARP,B4GALT6,LHX2,CNTN1,PREPL,C2CD2,CRY2,CLIP3,DCAF8,DGKG,RHOBTB1,ERCC2,EZH1,FGF13,FGFR1,FLNC,SARAF,DOT1L,CPLX2,LUZP2,STON1,LSAMP,MEST,MXI1,NF1,GPSM2,PPARA,SCN7A,SCAF8,SH3BGR,SH3BP2,SEPHS1,FNBP1,ZHX3,CEP68,PLCB1,DNMBP,TIMP4" Coexpression M2242 Category A genes: p53-dependent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.81E-06 6.60E-02 2.80E-04 2.77E-03 143 896 "ADD2,KIAA1324,SRPX,APBA2,PPFIA3,ARRB1,STK33,ASPA,SLC4A4,ADAM15,DST,CACNA1G,CA8,DDR1,VXN,LDB2,KRIT1,ENTPD2,KCNAB3,EVI5L,MAGI1,CLGN,NOG,UBE2L6,CACNA2D2,RAB33A,CLTC,CNTFR,CNTN1,COL11A2,AKAP5,CLIP3,SOCS5,APPL1,DOCK4,GPRASP1,RIPOR2,TBC1D5,GUCD1,SNAP91,DPH1,SEZ6L2,EDNRA,FEM1B,RASGRP1,RASGRP2,NCALD,MRPL10,FLNC,TRMO,GABRG1,GATM,IGSF5,LYVE1,RUNDC3A,MAP7D2,KCNMB4,GNAO1,LNX1,RASSF8,FRMD5,SHISAL1,C2orf72,NKD1,KNDC1,ITGA7,CDH20,KCNN1,KIT,ASPRV1,PACRG,GPR155,MAP4,MATN3,MEF2C,ADAM22,NRBP2,MYO5A,FXYD7,NDP,NNAT,NPR2,NTRK2,CLDN11,SEMA5B,PIK3R1,XRN1,PLEC,FXYD1,SLC25A23,STRN3,NECAB2,SH3KBP1,PPP2R2B,LRRN3,EPDR1,MAPK10,BCAS3,PTCH1,PTPRD,RIPOR1,BEND5,RNH1,KIAA0895L,STK32B,EMID1,MEG3,CSRNP3,KIF16B,SMARCD3,SNCA,CABCOCO1,KDM4B,FAM219A,FNBP1,SOX11,SST,SSTR2,APOM,SYNE2,ARC,COBL,MCF2L,DNMBP,DMXL2,TEK,TLR4,ANKRD24,NPL,PDIA2,BCL2L13,LAT2,LAMP5,ADAMTS9,RGS7BP,UBE3B,GJC2,NHSL1,IFT88,DPF3,SOCS4,LAS1L,SENP7" Coexpression 19235837-TableS2a Human Pancreas_Cavard09_736genes GeneSigDB 6.05E-06 6.87E-02 2.90E-04 2.87E-03 95 544 "FMNL2,AXIN2,SLC24A4,TBC1D14,OSBPL6,GPRASP2,LRCH2,PKP4,CDC14B,CADPS,ASGR1,RASL11B,EIF4G3,ATP1B3,BBS2,MPDZ,BMP7,ST3GAL5,CA4,SLC25A14,CAST,MAGI1,CHN1,CNOT8,NRXN3,HECTD1,MAP4K4,NECTIN3,SNCAIP,DZIP3,MATR3,SCRN1,DBN1,MYEF2,SACS,DNAH9,DMTF1,DNM1L,TSPAN5,EDN3,KLHL5,ASB3,EIF4G2,COPS4,STARD3NL,TUBD1,STX2,ARMCX1,POLK,FAM49B,ATP6V1H,FYN,CHL1,MALT1,NTNG2,STARD3,MAP4K5,MUM1,ACOT7,GABARAPL2,CPT1C,HSF2,LAMA2,LSAMP,MAP6,MYO9A,NPTX2,OCRL,ENPP2,SNX10,PKM,PPARA,PPP3CC,SLC26A11,PTPRG,RNASEL,CPEB4,SMARCA4,OGDHL,CDK5RAP2,NMNAT2,THSD1,NKAIN2,SS18,CAMTA1,TRIM2,HEY1,ACTR6,AMACR,USP1,ZNF184,ZSCAN26,HPS4,ITM2C,PCBP4" Coexpression 17483311-SuppTable1 Human Brain_Beier07_383genes GeneSigDB 6.16E-06 7.00E-02 2.94E-04 2.92E-03 55 269 "LRCH2,PARG,RGS9,CFLAR,PROM1,SYNJ2,ARHGEF7,IL33,CACNA1A,CAMK2G,SOCS6,STOML1,AKAP7,COL9A3,RTTN,ARHGAP24,CNNM1,FAM13A,MRO,HSD17B14,FGFR3,MPP6,GATM,GGT7,MALT1,RAB30,ZNF638,LNX1,BTN2A1,FAM107A,ATOH8,HNMT,INPP1,PACRG,MBP,BLOC1S2,NELL2,SLC11A2,PPARA,MAPK9,SNRK,PTCH1,PID1,FHOD3,KIF13A,FNBP1,MESP1,KIAA0930,OBSL1,SYNPO2,RUSC1,SSBP2,ZIC1,TCEAL7,PPP1R3F" Coexpression M4867 Genes down-regulated in comparison of NKT cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "SEMA4G,MARCH3,ADGRB1,FHL5,C1QL2,RGS6,VCAN,FAM169A,USP6NL,DCAF8,MYEF2,GUCD1,SNAP91,DNM1,ARRDC4,MAMLD1,MRO,C8orf37,STX2,TMEM132C,CORO2B,ALDH1L1,KIAA1958,LOXL3,GRIA2,GRIK5,FAM222A,IGFBPL1,KCND2,NPY,NPTX1,CNTLN,PTPRG,GAL3ST4,GSTCD,PLPPR3,KIF27,LGI3,CDH22,TIAM1,ICAM5,SYNPO2,FLRT2,VSNL1" Coexpression M6523 Genes down-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "ACTN1,NDRG2,RNF157,AP1M1,ENTPD6,ARHGEF2,NOG,C2CD2,KIAA0040,SCRN1,ARRDC4,FARSB,E2F5,C8orf37,RASGRP2,RABEPK,SLC43A2,ZNF391,ARMCX1,FECH,NBEA,MPP6,GABBR1,RAPGEF6,BACH2,METTL21A,MOV10,NFE2L2,NRCAM,NUCB2,PRKAR1B,QDPR,GAL3ST4,PTGR2,ZFP2,ZC4H2,SYPL1,TACR1,BHLHB9,METTL3,SSBP2,UBTF,TOM1L2,ZNF711" Coexpression M9924 Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 24h. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "AMH,EPB41L5,CPNE5,MYRF,CNTN1,SLITRK5,SCRN1,DBN1,RUSC2,HS3ST2,RASA4,TBC1D16,FLNC,TPPP3,GABRG2,TUBA8,AHDC1,PCDH17,KCNMB4,TDRKH,CIT,PSIP1,HLF,KCNF1,KIT,MID1,MOV10,MYT1,NPTX2,OPRL1,PCDH9,FXYD1,HYDIN,PTPRN,ROGDI,DUSP15,SLC8A1,SLC11A1,USP33,HECW1,ZNF423,STAC2,HEY1,ST8SIA2" Coexpression M3241 Genes up-regulated in comparison of naive B cells versus Ig isotype switched memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "ADORA1,PPP4R4,BCHE,RGS11,MTMR2,CAMK2B,CBS,RGN,MTMR7,DGKI,SULT4A1,PCYT1B,NECTIN3,AKAP12,FAM169A,HEPH,MFAP3L,DMPK,EDNRA,HIPK3,EYA1,OLFM1,HPCAL4,PPARGC1A,MATK,GIT1,NBL1,NPTX1,PDZRN4,MAGEL2,CNTLN,RASGRF1,RTN1,INTS9,LMO3,ARC,SYP,FAM189A1,PCDHA2,HIF3A,GPR161,HSPBP1,NDRG4,DPF3" Coexpression M10018 Genes up-regulated in macrophages: control versus tumor associated. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "NDRG2,FMNL2,PTCHD1,AMPH,PROM1,SEPT7,CHN1,ABCG2,CNTN1,CNRIP1,DCAF4,LYPD1,SACS,EDIL3,EDNRB,KLHL5,OPTN,PSMA3-AS1,FGF13,UBE2E3,ZNF559,GHR,DBF4,GPD2,UBE2QL1,MSL1,SCIN,IL6R,KCNN2,SAMD5,HS6ST3,NFE2L2,GPR85,GNG2,MAPK9,NDUFS7,RTN1,TMEM200C,SEPHS1,BTBD7,FAM126B,RBM26,ZNF621,TCEAL7" Coexpression M6356 Genes up-regulated in gamma delta T cells stimulated by phorbol myristate acetate and ionomycin [PubChem=4792;3733]: Vd1 versus Vd2. MSigDB C7: Immunologic Signatures (v6.0) 6.50E-06 7.38E-02 3.02E-04 3.00E-03 44 199 "METAP1D,AGT,CDK13,MAGED1,ARMCX2,ANKRD46,HIPK3,EGR3,C8orf37,PIPOX,RASL12,NSRP1,CORO2B,RACK1,SLC9B2,FYN,GAD1,SLC2A6,CREG2,LAMP2,MYH3,MYO7A,PCBP3,ENPP2,SMOX,MBOAT7,SLC26A11,QRICH1,KIF7,SLC25A36,SEC14L1,SH3GL3,ZNF667,NEK4,SYPL1,ZEB1,TCF12,ITGB3BP,BHLHB9,TTC3,ATP6V0E2,GDPD5,RNF170,FXR1" Coexpression M12004 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [GeneID=3065;3066] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.81E-06 7.73E-02 3.16E-04 3.13E-03 49 231 "GALNT16,PLEKHH1,MTUS1,KIAA1324,CALB2,NOG,NRXN3,CNRIP1,HAPLN1,RHOBTB1,DTNA,EBF1,EDIL3,KATNAL1,F8,FDFT1,FGF1,FGFR1,SCARA3,CSDC2,GLI2,PCLO,SYNPO,HMGCR,LSS,MATN2,MEIS1,MN1,PDE1C,PPP2R2B,PTCH1,TMEM255A,FIGN,TCP11L1,SCN2B,TMEM200C,SPP1,TCF4,NACC2,TK2,TNS1,TPM1,SSBP2,HIRA,MGAT5B,LAT2,TUBA1A,SEMA3B,JPH3" Coexpression M1475 Genes down-regulated in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.07E-06 8.03E-02 3.26E-04 3.24E-03 95 546 "ACADM,ADGRF5,BBOX1,CDC42BPA,ANK2,PARG,ASPA,SLC4A4,ATP2A2,AZGP1,MPDZ,DST,RAB29,CA4,CA12,CALB1,CALM1,CLDN10,KRIT1,USP2,RGN,SLC16A4,CLTB,RNF14,CRYM,FAM169A,CTH,PUM1,ARMCX2,MFAP3L,RHOBTB1,NR1D2,RCAN1,DNM1L,ANKRD46,SRRM1,ERBB4,SH3YL1,FECH,FGF1,UBE2E3,VTI1B,FOLH1,PDLIM5,FYN,GATM,TOX3,RAB40B,GRB10,DDX19B,HMGCL,HNMT,KHK,MIA2,MXI1,MYO6,OGG1,ENPP2,ABCB1,SERPINI1,PIK3C2A,PIK3R1,STRN3,PPM1B,PRPSAP2,PTH1R,PTPRD,QDPR,RDX,SLC25A36,ZC3H14,SALL1,SCP2,HSPA4L,SH3BGR,FNDC3A,R3HDM2,DZIP1,BTBD3,PDZRN3,CLASP2,LARP4,APOM,NEK4,KANK1,VPS13A,SYPL1,TRIM2,TEK,BEX4,PARD3,TST,TUBB2A,UGT8,RTN4" Coexpression M6689 Genes down-regulated in fibroblasts: untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 7.24E-06 8.23E-02 3.33E-04 3.30E-03 40 175 "OGT,LCORL,SFMBT2,ARNTL,ARRB1,DPY19L3,DST,VAX2,LRIG1,USP6NL,DGKG,KLHL3,NR1D2,FSD1L,PAN3,GTF2IRD2,ST6GALNAC3,GABBR1,GGT5,MALT1,TDRKH,MITF,MYO9A,NTRK3,ZDHHC8,SMOX,PRKCB,VPS13C,EML5,TCP11L1,SATB1,SCP2,ST8SIA1,KIF13A,ZHX3,TEX2,R3HDM1,KAT6B,CLIP2,PPP1R3F" Coexpression M9180 Genes down-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]. MSigDB C7: Immunologic Signatures (v6.0) 7.44E-06 8.45E-02 3.40E-04 3.37E-03 44 200 "ADCY6,RNF157,ARHGAP20,GPRASP2,MAP4K3,PKP4,CA8,CACNA1A,DDR1,ABCG1,GREB1,DAPK1,ANKRD46,ENO2,EPB41L2,ARMCX1,KIT,KTN1,HECTD2,SRSF12,KCTD6,MOV10,PTOV1,TMIE,SMOX,SLC25A23,PURG,MAPK7,ZNF354C,SATB1,ATXN2,ZNF821,RASA3,DZIP1,ST8SIA1,SPTAN1,MCF2L,AGTPBP1,TCF4,TP53BP1,TTC3,TUBB2A,TOM1L2,NDRG4" Coexpression M9184 Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus PBX1 and FOXP3 [GeneID=5087;50943]. MSigDB C7: Immunologic Signatures (v6.0) 7.44E-06 8.45E-02 3.40E-04 3.37E-03 44 200 "ACADM,ADCY6,RNF157,ARHGAP20,GPRASP2,MAP4K3,PKP4,DDR1,ABCG2,ABCG1,DAPK1,SHANK1,ANKRD46,EPB41L2,ARMCX1,FLYWCH1,SPECC1,B4GALNT1,SRCAP,ADAMTS6,SCIN,KIT,SMAD1,SRSF12,KCTD6,MX1,RTL5,SERPINI1,TMIE,SATB1,ATXN2,RASA3,ZFP30,ST8SIA1,SLC12A2,NFASC,AGTPBP1,TCF4,SLC44A1,TP53BP1,CDK20,TTC3,BCL2L13,PARP11" Coexpression M3134 Up-regulated genes constituting the molecular signature of Burkitt 's lymphoma. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.58E-06 8.61E-02 3.44E-04 3.41E-03 16 43 "APBB2,BMP7,WASF1,PTBP2,NSG1,BACH2,SUGCT,FHOD3,SMARCA4,SOX11,SSBP2,TUBB2A,UCHL1,PRDM10,TUBA1A,HNRNPA3" Coexpression M9238 Genes up-regulated in pancreatic CD8 T cells from mice with: type 1 diabetes mellitus versus healthy controls. MSigDB C7: Immunologic Signatures (v6.0) 7.70E-06 8.75E-02 3.49E-04 3.46E-03 43 194 "AMPD3,ZBTB10,DOCK11,ANKRD44,SIPA1L1,DZIP3,PUM1,CYBB,DOCK2,DTNB,ABCC5,SEMA3D,KMT5B,RASGRP2,EVL,FLT1,ATP6V1H,CELF1,OGA,CHL1,ADAM28,AP4S1,PSIP1,BACH2,ZNF678,ZFYVE27,CHIC1,SNX10,VPS13C,SNRK,RIPOR1,TTC13,ZNF844,KHDRBS2,FBXO11,SLA,SP4,ZSCAN29,PUM2,LAT2,ZNF28,SLC30A4,SENP7" Coexpression 18787207-TableS2 Mouse Viral_Craft08_969genes GeneSigDB 8.26E-06 9.38E-02 3.72E-04 3.69E-03 111 664 "RNF157,AXIN2,TAOK1,SEMA6A,SPOP,FAM135A,LRFN1,EP400,LGR5,CASK,MARCH3,PTCH2,NUMB,ADGRB2,RGS11,FUBP1,KALRN,PTBP2,CCNH,CACNA2D2,SRSF11,FOXN3,RAB28,PLAA,ARMC8,RCHY1,FAM171B,SNCAIP,BOC,TCAF1,HDAC4,RASSF2,MATR3,DBT,B3GAT3,TMCC2,SLC29A4,ARRDC4,DNAJB6,EBF1,FSD1L,PHF20L1,PCOLCE2,STX2,ERBB2,CDKL3,KATNAL1,ATP5PD,SYNCRIP,FLNC,FLT1,ATP2C1,DOT1L,RAPGEF6,MTHFD2,AHDC1,TXNL4A,CIT,SOX21,AGBL5,ZDHHC15,LIMS1,NEK1,CNOT4,PCBP3,OGG1,TREM2,PDPK1,PLEC,MAPK10,ANKHD1,RDX,RGS3,RPE,FBXW7,RXRA,SALL1,MRAS,CHD9,PPP4R3A,CCDC88A,EPC1,FAM126B,BDP1,SOX11,IZUMO4,UNC5B,POGZ,ZC3H4,PRRC2C,SYN1,ARC,CAMTA1,SMG6,CLASP1,PCDHA1,HIF3A,SIK3,PARD3,CABIN1,STXBP4,RICTOR,ZIC2,SPIRE1,ZFAND5,RTN4,HNRNPA3,PHTF2,ACTR3B,FXR1,AP3B2" Coexpression M11615 Genes down-regulated in metastatic tumors from the whole panel of patients with prostate cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.53E-06 9.69E-02 3.82E-04 3.79E-03 60 305 "SYS1,AXIN2,FAM135A,EPB41L5,BCAS1,ALDH7A1,AZGP1,BMP7,CACNA2D1,CD38,CFL2,FOXN3,SLIT2,ARHGEF10,BOC,SPOCK3,EGR3,PCOLCE2,HSD17B14,ERBB2,RASL12,MRVI1,ARMCX1,FGF13,PSD2,POMT1,GHDC,IQGAP2,GSTM5,FAM107A,LSAMP,PPM1L,MN1,MX1,NBL1,IDNK,NEFH,NINJ2,CNTN3,PDE4B,PCDH18,PDZRN4,PTN,PTPRN2,ROGDI,GTDC1,ZNF532,ROBO2,SCN7A,ASAP3,FHOD3,LIMS2,LHPP,MIR100HG,TMEM150C,TNS1,SYNPO2,RBFOX3,SLC30A4,DNALI1" Coexpression M1113 Up-regulated genes from the set C (Fig. 5a): specific to cells expressing AF4-MLL [GeneID=4299;4297] fusion protein alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.55E-06 9.71E-02 3.82E-04 3.79E-03 39 170 "LCORL,DPY19L3,CLDN10,SRSF11,FOXN3,FAM149A,LRIG1,GPSM1,B3GAT3,ZC3H11A,USP3,SLC12A6,PDCD6IP,E2F6,KCTD3,SPEG,RASL12,PDLIM5,TPK1,B4GALNT1,MAP4K5,SLC11A2,PDE1C,PLEC,PTPRD,FAT4,RFX3,RPS20,TNFRSF19,PUF60,FNDC3A,PDZD2,TSNAXIP1,ERBIN,TCF4,ZBTB38,PPP1R3F,FAM13C,NETO2" Coexpression M8645 "Genes up-regulated in the nucleus accumbens (a major reward center in brain) 2 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.58E-06 9.75E-02 3.82E-04 3.79E-03 17 48 "APBA2,CADPS,ARHGEF25,CCK,OLFM1,SEPT9,STMN2,STMN1,SMAD1,MEF2C,NEFM,NEFH,NPTX1,SERPINI1,FHOD3,TUBB2A,VSNL1" Coexpression 18504433-SuppTable1 Human Liver_Liao08_600genes GeneSigDB 9.01E-06 1.02E-01 4.00E-04 3.97E-03 94 542 "PKP4,CDK13,EIF4G3,BARD1,MTMR2,CA12,ARHGEF1,CBFA2T2,ARHGEF2,NUMBL,CLTB,MAP4K4,COL11A2,FAM171B,SH2B1,CSNK1E,VCAN,DBN1,MYEF2,B3GAT3,RHOBTB1,SLC29A4,DTNA,DUSP9,DNM1L,ANKRD46,PLXNC1,ENO2,MFSD10,RACK1,GORAB,SYNCRIP,EFCAB2,ATP2C1,GABBR1,MTHFD2,SEPT9,TOX3,KIAA1958,MAP7D2,GNG4,PRRC2B,SLC2A6,PACSIN2,ATXN2L,KCNH2,KIF2A,MAP2,MAP4,MBNL1,SCAMP5,NACA,NRCAM,ZNF827,PCSK5,PDCD2,PFKFB4,OLA1,PKM,SMOX,MAPK3,VPS13C,PTK2,SUSD4,FIGN,SLC25A36,ZNF532,ROBO1,ROBO2,GLDN,HUNK,FERMT1,HKDC1,FHOD3,SLC6A8,ARFGAP1,SNAP25,TMCC1,ZNF302,PLCB1,AGTPBP1,TCF12,PUM2,CBX5,TPM2,TRPS1,SSBP2,TUBB2A,UCHL1,ZIC2,ZFP41,STOX2,NAV3,NETO2" Coexpression M6691 Genes down-regulated in fibroblasts: interferon alpha versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 9.42E-06 1.07E-01 4.16E-04 4.13E-03 41 183 "ACTN1,PKP4,ARNTL,ARRB1,DPY19L3,GPR146,DDR1,LARGE1,LHX2,VAX2,CRMP1,DAPK1,ARMCX2,GPHN,MEX3B,NOP56,GCNT2,GGT5,HPGDS,TDRKH,SERP2,GUCY1B1,BACH2,SYNPO,LRRC75A,ITGA7,MPP2,ZC3H12B,PCBP3,TMOD2,ZDHHC8,NLE1,JAKMIP1,SLC25A23,PRKCB,SATB1,ST8SIA1,ZFP1,LHPP,PHLDB1,MGRN1" Coexpression M2018 Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.55E-06 1.09E-01 4.20E-04 4.17E-03 19 58 "AGT,AMPD3,DDR1,DAPK3,SLC25A18,ECM2,PIPOX,FGF1,GPD1,PLCD4,GPR173,MASP1,ZSCAN2,C1orf54,GAL3ST4,KCNIP3,TNS2,TIMP4,PLPPR2" Coexpression M10332 Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.58E-06 1.09E-01 4.20E-04 4.17E-03 20 63 "BIN1,ATP2A2,ARHGEF25,CCK,CLTB,ENO2,PTK2B,GPD1,GRIA2,NPTX1,PKM,PPP3CA,PRKCB,MAPK3,RASGRF1,FBXW7,STXBP1,SYP,SYT1,KCNAB1" Coexpression M6110 Genes down-regulated in patients at the incipient stage of Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-05 1.15E-01 4.40E-04 4.37E-03 38 165 "ACTN1,APC,RGS20,ATP2A2,ADGRB2,CLDN10,USP6,DLGAP2,CLIP3,CSNK1G3,ARHGEF4,RIMS2,TENM1,DENND4A,FHL1,SEC23B,CAMKK2,GABRB3,B4GALNT1,TOX3,GLUL,FAM69A,OPA1,FSD1,PPP3CA,RGS4,ROBO1,RPE,KCNIP1,SEC31A,ELMO2,FAIM2,DDN,SST,NSFL1C,ZMAT3,TRO,TTC3" Coexpression 18535662-TableS1a Mouse Lymphoma_Wu08_1813genes GeneSigDB 1.01E-05 1.15E-01 4.41E-04 4.38E-03 144 913 "NDRG3,MTA3,AP2A2,OSBPL1A,TAOK1,C1QTNF3,MAP4K3,MYH7B,APBB2,FAM131A,PHYHD1,CASK,ARHGDIG,CHID1,ATP1B3,ATP2A2,ATP6V0A1,ADAM15,BID,ST3GAL5,SYNJ2,SGCE,CACNA1G,CALM1,CAMK2G,SPAG9,ARHGEF25,CDH2,LRRFIP1,CDO1,FOXN3,CHN2,TPP1,CNN3,IQCK,COL11A2,MAGED1,CLIP3,ARHGEF10,SIPA1L1,PDE4DIP,PNPLA8,GPSM1,BOC,TCAF1,SEC16A,CD99L2,CDON,FIS1,ASB3,STARD3NL,LRRC17,RASGRP2,ERBB2,SPEG,EXTL2,RPS6KC1,TAOK3,FCGRT,FDFT1,IP6K2,VTI1B,ANKFY1,JKAMP,ATP6V1H,ERGIC3,SARAF,FYN,STON1,PRDM5,GSN,GSTM5,ZHX1,GABARAPL2,SMAP1,IGF1,IL6ST,JAK2,METTL21A,LAMP2,LIFR,MAT2A,MEST,PTOV1,TAGLN3,NFE2L2,NUCB2,ZFYVE21,GPSM2,PLCD1,SMOX,PPP3CC,PRKAR1B,MAPK3,EPDR1,MAPK7,RELN,APTX,PTPN13,TRIM68,RPS6KA2,HUNK,SCP2,FNIP1,TNFRSF19,SEC14L1,GALNT10,RASA3,CHD9,FNDC3A,SEC31A,ARHGEF40,CDK5RAP3,SLC14A1,ABTB1,LIMCH1,LMBRD1,USP33,GLT8D1,SEPT8,STXBP1,PJA1,TCF4,AKTIP,TK2,TPM1,PDSS1,AMACR,TRPS1,SSBP2,UBC,TOM1L2,VLDLR,TBC1D15,WIPF1,NDRG4,POLR3H,MEIS3,MFF,NT5M,NAV3,MSRB3,ZDHHC20,NETO2" Coexpression M1539 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) after 5 days of cocaine [PubChem=5760] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-05 1.22E-01 4.66E-04 4.62E-03 23 79 "ACTN1,ADORA1,ADORA2A,AP2A1,CAMK2A,CCK,SPOCK2,ELN,CORO2B,BAIAP2,GAD1,KCND2,NELL2,PALM,PDE4B,PDE1B,FBXW7,STX1B,SEC14L1,SH3GL3,STXBP1,SYP,HPS4" Coexpression 18308945-Table1 Human StemCell_Huang08_100genes GeneSigDB 1.13E-05 1.28E-01 4.87E-04 4.83E-03 25 90 "PROM1,B4GALT6,CRHBP,CHRDL1,PAN3,HPGDS,GUCY1A1,HLF,KIT,LMO2,MEIS1,MEST,MYCN,DPY19L2P2,PTPRD,BAALC,ATP8B4,SLC2A5,PDZD2,ANKRD28,METTL3,SSBP2,GUSBP1,ZNF711,MSRB3" Coexpression M3118 Genes up-regulated in comparison of naive T cells versus memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.16E-05 1.31E-01 4.97E-04 4.93E-03 43 197 "METAP1D,KLHL13,GPRASP2,PITPNM2,APBA2,SFMBT2,SLC2A11,DDR1,SCARB1,GPRASP1,SNPH,ARMCX2,KCTD3,SCML2,FCGRT,NBEA,RAPGEF6,ADGRA3,ZNF496,BACH2,HSF2,ZNF546,MEST,DNHD1,SLC11A2,NUCB2,PCSK5,RETREG1,LRRN3,CEP41,TUG1,BEND5,GAL3ST4,SATB1,BTBD3,SNRPN,ZC4H2,RNF175,PRRT1,TOM1L2,CIAPIN1,AMN1,KLHDC1" Coexpression M17163 Genes up-regulated at early fetal liver stage (embryonic days E11.5 - E12.5) compared to the late fetal liver stage (embryonic days E14.5 - E16.5). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.17E-05 1.33E-01 5.01E-04 4.97E-03 38 166 "TMEFF1,WASF1,PTBP2,LDB2,LARGE1,SOCS6,ARMCX2,HEPH,GOLT1B,EDNRB,SEMA3D,PCOLCE2,ARMCX1,FGF13,FGFR1,EVL,LPAR4,MEST,MYCN,NNAT,PKM,KCTD15,LRP12,PTN,PTX3,SATB1,SH3GL3,SLC12A2,SMARCD3,PDZRN3,RBM34,PDZD2,ZNF423,SYNE2,TRO,TRPS1,TTC3,RPRM" Coexpression 15090461-Table3 Human StemCell_Wagner04_36genes GeneSigDB 1.19E-05 1.35E-01 5.06E-04 5.02E-03 13 31 "PROM1,ELN,FCGR3A,FHL1,GUCY1B1,IFI16,ABCB1,SLC2A5,SPP1,RGL1,NUDT10,PLCB1,LAT2" Coexpression 20161705-Table2 Mouse EmbryonicStemCell_Layden10_73genes GeneSigDB 1.21E-05 1.37E-01 5.14E-04 5.09E-03 21 69 "ADORA1,ADORA2A,LGR5,CNR1,EDNRB,CELSR3,GABBR1,GPR162,CRCP,MCHR1,GPR34,GRM2,GRM8,GPR62,OPRL1,P2RY1,GPR85,SSTR1,SSTR2,TACR1,ADGRL3" Coexpression 15720813-Table2 Human Brain_Hoelzinger05_59genes GeneSigDB 1.24E-05 1.41E-01 5.26E-04 5.22E-03 18 54 "ARHGEF7,CHN1,CRYM,EGFR,RCAN2,GABRG2,HLF,MEF2C,TAGLN3,NELL2,NPTX1,ENPP2,SERPINI1,KLK6,PTPRN2,SMARCC2,NEK4,FIP1L1" Coexpression M13661 The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.26E-05 1.43E-01 5.31E-04 5.26E-03 85 482 "MTA3,MTUS1,ALCAM,BCAS1,SFMBT2,ARRB1,NCOA1,RASL11B,DOCK11,BMP7,SYNJ2,HIP1R,CCPG1,CFL2,COPB2,SOCS6,CLTC,QKI,RUBCN,DBI,MFAP3L,GUCD1,SGSM2,CPEB2,ABCC5,PHF20L1,MBNL2,LINC-PINT,GOLGA7,VPS13B,EPB41L2,ERBB2,ERBB4,FAM198B,FGF12,FGF13,FUT9,MALT1,LNX1,ADAP1,ATP2B1-AS1,GRB10,DIDO1,GSN,ZHX1,ICA1,INPP1,LSS,MATN3,MBNL1,COL28A1,NCAM2,NF1,SLC11A2,NUCB2,ZNF827,PMP22,STRN3,EPB41L4B,PTPN13,RIPOR1,ZDHHC4,C12orf49,SGSM1,GALNT10,WDR37,SLC12A2,LIMCH1,PDZD2,FNBP1,NXT2,KLHL7,TACC1,TCF4,AKTIP,NACC2,BEX4,RPRM,GORASP1,TBC1D15,RICTOR,REEP1,SPIRE1,RNF103,FAM219B" Coexpression M2605 Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.27E-05 1.45E-01 5.36E-04 5.31E-03 91 525 "ABHD6,C3orf14,ADCY6,ADRB2,MTUS1,SEMA6A,TMEFF1,ZSCAN18,AZGP1,NRP2,GYG2,ENTPD6,ZBED1,TPP1,CNN3,LETMD1,CPS1,PREPL,APPL1,CTH,SEC14L5,HDAC9,IP6K1,ARMCX2,DMD,DPP6,DPYSL2,EDNRB,MBNL2,EIF4G1,PCOLCE2,ETV1,GMPR2,DLC1,ST3GAL6,FDFT1,NSG1,OGA,FYN,GALC,ALDH1L1,SPIN1,GLUL,GPR37,PCLO,HNMT,ITPKB,IPO5,MATN2,MBNL1,MEST,DPY19L2P2,PDE4B,PDE4D,ENPP2,SERPINI1,PIK3R1,PMP22,ING3,PRKACB,MASP1,SNRK,FAM184A,SLC25A36,ZNF532,ROBO1,RPL15,SATB1,ATXN7,SYBU,SNCA,ZNF415,SPP1,ERC1,PEG10,ZNF423,ZC3H13,SS18,NEK4,GPR161,ZMAT3,MTMR14,TLR4,BEX4,SSBP2,GORASP1,ZBTB38,PLSCR4,EPM2A,HRASLS,FXR1" Coexpression M11504 "Genes down-regulated in prostate cancer vs benign prostate tissue, based on a meta-analysis of five gene expression profiling studies." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.30E-05 1.48E-01 5.47E-04 5.42E-03 15 40 "DST,SGCE,CALM1,AKAP12,SCRN1,FHL1,GATM,GSN,MEIS1,MEIS2,PMP22,SPART,ST5,TACC1,TPM2" Coexpression M9862 Genes up-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.32E-05 1.50E-01 5.51E-04 5.46E-03 43 198 "APBA2,CDC14B,LINC00847,PROM1,SGCE,CHN1,CLCN3,LETMD1,ABCG1,CSF1,JAKMIP2,USP3,FRY,DCTN4,PTK2B,PCYOX1,GABRG2,GALC,BRD8,KCNMB4,ADGRA3,PRUNE2,HMGCL,RBPJ,METTL21A,KCNN3,GPR155,AFF1,NCF2,ZNF671,SCAF8,RCOR3,MBD5,PDZD2,SPATA7,CEP68,ZC3H4,PLCB1,C12orf76,CBX5,CCDC14,VPS35L,MDH1B" Coexpression M3335 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.47E-05 1.67E-01 6.10E-04 6.05E-03 61 317 "APLP1,CDK10,TMEFF1,ADAM15,CACNA1G,WASF1,MYRF,BAIAP3,SPAG9,CLTC,SLC4A8,AKAP12,PDE4DIP,TCAF1,DAPK3,DBN1,SEZ6L2,AASS,CDKL3,TAOK3,FER,FHL1,CGREF1,CYP46A1,GLYR1,STARD3,GSN,HBA1,MAN1B1,ITGA7,KHK,L1CAM,MEF2C,ENPP2,SERPINI1,GPSM2,PLEC,SEPT4,PRKCB,PRPH,RADX,NUDT11,SBF1,SH3GL3,PPM1E,ANKRD6,SLC6A8,SMARCD3,IFT122,ZSWIM8,PEG10,ZBTB43,CAMTA1,DOCK9,BEX4,RUNDC3B,TST,SGK3,PLPPR2,TUBA1A,SLC17A7" Coexpression 18310505-TableS1 Human StemCell_Matushansky08_886genes GeneSigDB 1.50E-05 1.71E-01 6.19E-04 6.14E-03 114 695 "ASIC1,OSBPL1A,ADGRF5,OGT,APAF1,CDK10,AZGP1,BARD1,CFLAR,GYG2,CA12,DDR1,CALB2,CALM1,SPAG9,PRC1,CDC25B,CLGN,QKI,IQCK,COL4A5,C2CD2,VCAN,CNTNAP2,PPP6R2,ZFYVE16,TBC1D5,DDX46,FCF1,EIF1,TUBD1,PIPOX,EXTL2,EYA1,DLC1,FHL1,SEC23B,VTI1B,FOXO3,EVL,FOLH1,SMC2,GALC,BRD8,MSL3,GLUL,GNAO1,FERMT2,STON1,CIT,GSN,HBA1,MAN1B1,IL6ST,LAMP2,MAT2A,MT1M,NEFM,NNAT,NUCB2,OGG1,PCDH9,PFKFB3,SMOX,EPB41L4B,PRPSAP2,PTPRD,RAD17,RDX,RXRA,RMI1,S100B,FNIP1,TRA2B,ZFP30,FAM102A,SHMT2,AMBRA1,DZIP1,PKNOX2,ZNF334,ELMO2,ATF7IP,LIMCH1,GLT8D1,PEG10,ST5,SEPT8,RGL1,SUPT5H,ARHGEF9,DNAJC9,TACC1,ANKRD12,SLC19A3,SLC35G2,ZMAT3,TIAM1,TNS1,CDK20,METTL3,TRO,RUSC1,UBE2H,WIPF1,GUSBP1,ZIC1,ZNF184,ZFAND5,ADAMTS9,FIP1L1,ITM2C,RTN4,PHTF2" Coexpression M8119 Genes up-regulated in NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]. MSigDB C7: Immunologic Signatures (v6.0) 1.50E-05 1.71E-01 6.19E-04 6.14E-03 43 199 "OSBPL1A,ZNF687,SFMBT2,TMEFF1,ADAM15,GPR146,CD38,RBM39,PDE4DIP,PPP1R16B,MATR3,NR1D2,SEMA3D,FRY,TNK2,EMX2,EPB41L2,ERBB2,FAM198B,STON1,TOX2,IRF8,RBPJ,IL6ST,IPO5,STXBP5,SMAD1,KCTD6,MYO5A,GPSM2,TRHDE,PTK2,FNDC3A,ZKSCAN3,MYO16,CLASP2,POGZ,ERBIN,EXOC7,TCF4,ZFP90,RGMB,AMZ1" Coexpression M7306 Genes down-regulated in lymphocytes treated with TNF [GeneID=7124] for 2h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 1.50E-05 1.71E-01 6.19E-04 6.14E-03 43 199 "CLK4,TMCC3,PHF12,TNRC6C,ZFYVE28,BACH1,CASTOR3,CCPG1,MS4A7,CNN3,PNPLA8,ZFYVE16,IST1,FRY,KMT5B,GOLGA7,PAN3,ZNF585B,PRKAG2,ZMAT1,ATP2B1-AS1,BTN2A1,GPR155,ZNF655,SLC26A11,PTPRE,ZNF844,FAM161B,FBXO11,BTBD7,GKAP1,ABTB1,MYCBP2,KDM4C,ARHGAP26,ERBIN,ANKRD12,DNMBP,ZNF189,ZFAND5,AMN1,NLRP3,RNF146" Coexpression M6881 Genes down-regulated in monocytes after HCMV infection: untreated versus BAY 11-7082 [PubChem=5353431]. MSigDB C7: Immunologic Signatures (v6.0) 1.52E-05 1.73E-01 6.22E-04 6.17E-03 39 174 "AXIN2,SYT13,SFMBT2,EIF4G3,PRMT9,ZMYM4,MAP4K4,MAGED1,CLOCK,SIPA1L1,PPP6R2,YTHDC1,FAM107B,MBNL2,GPHN,PTK2B,NEU3,FUT10,AGFG1,LRRCC1,IL6ST,JAK2,HECTD2,NF1,OCRL,PGAM2,SH3KBP1,PEX2,SLC25A36,CLIP1,LMBRD1,USP33,UHRF1BP1L,MGRN1,ARHGAP9,ZNF106,TTC3,ZBTB38,DHX33" Coexpression M2840 Genes up-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.52E-05 1.73E-01 6.22E-04 6.17E-03 70 379 "RALGAPA1,ADCY6,PLEKHH1,KIAA1211,KIAA1324,BCAS1,SFMBT2,ARRB1,ADGRB2,CA12,HIP1R,LONRF2,LARGE1,CACNA2D2,CHN2,SLC4A8,ABCG1,KIAA0040,RUBCN,TCAF1,ZFYVE16,MYEF2,SEC16A,USP3,TBC1D16,STRADA,EVL,POMT1,LNX1,CACFD1,ICA1,MAPT,MYCN,MYO6,NACA,NUCB2,KCTD15,PPP2R2C,MAPK9,SLC26A11,CYBC1,ELOVL2,NKAIN1,PRRT2,NBPF1,MTERF2,SMARCC2,KDM4B,ZSWIM8,CLSTN2,POGZ,PRRC2C,TMEM150C,ASTN2,IQCE,TBL1X,MGRN1,KAT6B,TRPS1,RUSC1,TTC3,NPDC1,ZNF24,ATP6V0E2,ZNF74,SH3GLB2,INTS3,DNALI1,SLC38A1,RNF103" Coexpression 15902281-TableS1a Human Leukemia_Schoch05_1052genes GeneSigDB 1.53E-05 1.74E-01 6.23E-04 6.17E-03 80 449 "ADCY8,MTUS1,RGS20,ZBTB10,ADGRB1,CA8,CALB1,RUNX1T1,MTMR7,DLGAP2,BAG4,ENTPD4,ARHGEF10,RIMS2,DPYSL2,E2F5,ANKRD46,EEF1D,PHF20L1,EGR3,GOLGA7,VPS13B,NCALD,EYA1,PTK2B,DLC1,FDFT1,FGFR1,SCARA3,FAM49B,ATP6V1H,KHDRBS3,STAU2,SARAF,ADAM28,GFRA2,FUT10,STMN2,HAS2,ZHX1,HNF4G,KCNQ3,MATN2,MMP16,MSR1,NEFM,ENPP2,DUSP26,PLEC,PURG,LRP12,PPP3CC,PKIA,PTK2,PEX2,OXR1,ZMAT4,ZFHX4,CCDC25,BAALC,RPS20,PUF60,R3HDM2,SYBU,SLA,PREX2,LGI3,INTS9,ARC,TACC1,PDLIM2,ZFPM2,ZNF34,HEY1,CSMD1,TRPS1,SGK3,WRN,FZD3,RNF170" Coexpression 11731795-SuppTable1 Human Lymphoma_Armstrong02_100genes_UnderExpressed GeneSigDB 1.54E-05 1.75E-01 6.24E-04 6.19E-03 24 86 "DDR1,LARGE1,MAGED1,AKAP12,DBN1,E2F5,FGFR1,IFI16,LIG4,SMAD1,NPY,SCHIP1,PRKCB,PTK2,RBBP6,ZNF821,SMARCA4,ZNF423,SPTAN1,CEP68,RGL1,TCF4,PARD3,ZNF45" Coexpression M9100 Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 [GeneID=22807]. MSigDB C7: Immunologic Signatures (v6.0) 1.60E-05 1.81E-01 6.45E-04 6.40E-03 37 162 "ADRB2,SORCS2,SPOP,CARNS1,AMPD3,ADAM15,EVI5L,ANKRD44,RIPOR2,CD99L2,SRPK3,RASGRP2,STX2,IQGAP2,MSTN,PADI2,HP,KHK,NCOA7,GPR155,MATK,AQP11,SLC25A23,TATDN3,DEF8,PTPRE,TUG1,EMID1,MYO18A,ST6GAL1,SLC14A1,ELMO2,SULF2,CLASP1,CDK20,CELF4,SPIRE1" Coexpression M8448 Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [GeneID=23512] and EED [GeneID=8726] Polycomb proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.63E-05 1.86E-01 6.46E-04 6.41E-03 108 652 "ADCY8,SLC24A4,KIAA1324,ARHGAP20,LRCH2,LGR5,ZFYVE28,RGS20,CHRD,CACNA1G,CACNA1B,CH25H,CBLN1,DGKI,CRLF1,SLIT2,LHX2,VAX2,CNTFR,COL4A5,NRG2,CNRIP1,PDE4DIP,DGKG,SV2B,SPOCK3,DLX1,GRIN3A,CNNM1,EGR3,TMEM132E,EPHB1,ERBB4,HPCAL4,ZMYND15,RASL10A,TPPP3,B4GALNT1,PCDH17,GHR,NTNG2,DCLK2,GPR12,STMN2,GRIA2,PTPRT,GUCY1A1,ATOH8,HBA1,FRMD3,SHISA6,LRRTM1,ITPKA,KCNQ3,MAPT,MT1M,HS6ST3,LAYN,NEFM,NFIX,NPTX1,NTRK2,PAX6,DPY19L2P2,PCDH8,SLC10A4,TMOD2,PLEC,PMP22,MAPK4,DCHS2,SUSD4,RASGRF1,CRTAC1,STK32B,RYR3,SEMA6D,LRFN5,PPM1E,SHC4,FAM81A,PKNOX2,TRIM67,PDZD2,CLSTN2,MESP1,SSTR1,SSTR2,ASTN2,TAL1,ADGRL3,CHST8,HEY1,ICAM5,CSMD1,DOK6,ANKRD20A2,FLRT2,WNT7A,KCNK12,ZIC1,TRIM9,LAMP5,SLC30A3,SLC30A4,KCNAB1,DPF3,ST8SIA2" Coexpression 19861896-SuppTable1 Human Brain_Castells09_424gebes GeneSigDB 1.65E-05 1.88E-01 6.46E-04 6.41E-03 69 373 "AGT,ALCAM,GAS7,BCAS1,ALDH7A1,ATP6V0A1,RIPK1,CDH2,PLEKHB1,LHX2,RAB33A,CNTN1,CLIP3,SIPA1L1,SPOCK2,ELMO1,TMCC2,DNM1,EBF1,EIF5,CERCAM,ENO2,APC2,ETV1,TUBB3,FCGRT,MAD2L2,TPPP3,FYN,CHL1,GAD1,FREM1,GHR,PPARGC1A,SPIN1,GSN,GUCY1A1,HLF,IGF1,IL6ST,JAK2,LAMP2,STMN1,LYPLAL1,NCAM2,NOVA1,NRCAM,IGSF11,PDE4B,SMOX,PSAT1,EXOSC10,SCHIP1,RETREG2,PRKACB,PTPRN,BAALC,SATB1,RASA3,SH3GL3,KIF16B,CPEB3,FNDC3A,ST6GAL1,SMARCD3,SUPT5H,TNS2,TEK,TUBA1A" Coexpression 16168083-Table2 Human Sarcoma_Henderson05_66genes GeneSigDB 1.65E-05 1.88E-01 6.46E-04 6.41E-03 18 55 "SPARCL1,LGR5,CDH2,CHN1,ABCG2,PDE4DIP,EMX2,ETV1,FGF1,PRUNE2,ACOT7,EPB41L4B,DIRAS2,PTPRD,PTX3,ZFHX4,SOX11,TPM2" Coexpression M10156 Genes up-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [GeneID=5077;2308] fusion protein off an adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.66E-05 1.88E-01 6.46E-04 6.41E-03 19 60 "LGR5,TMEFF1,SLIT2,CNR1,DMD,PLXNC1,CALCRL,TPK1,PCDH17,LIFR,KITLG,LRRN3,PTPRG,SGK1,PEG10,CLSTN2,KAT6B,TUBB1,PLSCR4" Coexpression 16455954-TableS2 Human StemCell_Dekker06_439genes GeneSigDB 1.67E-05 1.89E-01 6.46E-04 6.41E-03 70 380 "USP31,MTUS1,HECW2,AMPH,PRX,ATP1B3,DPY19L3,BID,CBS,CDH2,CDO1,MAP4K4,HOMER3,LRIG1,FAM169A,GPSM1,DOCK4,DAPK3,DBN1,FAM107B,DOCK2,EBF1,EDIL3,EDN1,VPS13B,REEP2,ABCA8,FAM198B,DLC1,FHL1,SYNCRIP,KHDRBS3,RAPGEF6,GDF1,GGT5,RASSF8,IL6ST,LIMS1,MYO5A,ZNF827,PDE3A,PDE4B,SCHIP1,MBOAT7,PPP3CA,PRKACB,PKIA,PTX3,RGS3,S100B,SEC14L1,GALNT10,SUPT20H,ST6GAL1,PREX2,DHX30,SLC11A1,SNCA,SYT1,TACR1,DNMBP,TCF4,CLASP1,TRIO,UBE2H,UGT8,FLRT2,ZFAND5,PCBP4,FRMD6" Coexpression M8662 Genes down-regulated in bone marrow-derived macrophages: untreated versus stimulated by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.69E-05 1.92E-01 6.46E-04 6.41E-03 40 181 "RNF157,AP2A2,UPRT,NCOA1,CERS5,ARHGEF1,FOXN3,CLTC,C2CD2,GAPVD1,SEC16A,DOCK2,SNX29,VPS13B,SLC43A2,FER,SESN1,MAN1B1,SFXN5,LMO2,MBNL1,MEF2C,SCAMP5,TBC1D25,PPP3CA,SNRK,ZDHHC14,UBR7,RXRA,SEC14L1,KIF16B,ST6GAL1,ATF7IP,FNBP1,ATMIN,RGMB,ZBTB14,MAP3K12,HPS4,ADAMTS10" Coexpression M15103 "Genes up-regulated in A4573 cells (Ewing's sarcoma, ESFT) after knockdown of BMI1 [GeneID=648] by RNAi." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.71E-05 1.94E-01 6.46E-04 6.41E-03 96 565 "ASIC1,USP31,FAM135A,SUGT1P4-STRA6LP-CCDC180,APLP1,LGR5,IGDCC4,TMEFF1,ADGRB2,BMP7,CACNA1G,WASF1,PRC1,SCARB1,KCNAB3,NOG,TAOK2,QKI,TMEM184B,RAB26,BAG4,CRMP1,NCOR2,CRYM,CS,CNTNAP2,KIAA0408,BOC,SLC29A4,CDON,SHANK1,EDIL3,HIPK3,AASS,CERCAM,ELN,LRRC17,STX2,CD320,TBC1D16,PRMT5,SEC24B,OLFM1,FGF13,AGAP3,TPPP3,GPR162,TNRC6A,PRRC2B,DIDO1,ATE1,GSN,IDH3A,RBPJ,IL6ST,ITPKA,CYP27C1,ZNF92,NELL2,NFYA,PDE4A,PDE1B,DUSP26,KCTD15,PLTP,MBOAT7,FSD1,PPP1R1A,PKIA,MAPK3,RDX,RGS4,C12orf49,BAALC,HUNK,PEG10,SS18,MPRIP,VWCE,GALNT17,TPM1,TPM2,NEIL2,RUSC1,TUBB2A,UBTF,PLPPR2,CLDND1,ZIC2,FTSJ1,MAP3K12,PRDM8,SLC17A7,PCBP4,ZDHHC20,SOCS4" Coexpression M5494 Genes up-regulated in comparison of macrophages versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "ASPHD1,DDO,NUMB,DST,CD86,CHN2,CREM,IPCEF1,ERC2,DBI,HS3ST2,DPYSL2,RCAN1,TAOK3,DLC1,FHL1,FOXO3,FLT1,GABRA3,GCNT2,SPIN1,ADGRA3,GPD1,GPD2,CIT,ACOT7,HP,RBPJ,MYO6,OCRL,PDE4A,DIRAS2,PTPN13,ZMAT4,TCP11L1,SLC11A1,SLC22A4,ITPRID2,CHST8,TLR4,BEX4,PLPPR2,NLRP3" Coexpression M7495 Genes down-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "NDRG3,HACE1,EPB41L5,MADD,MARCH3,MYOM1,ST3GAL5,CLDN10,CBFA2T2,CD38,CSNK1G3,PITPNC1,E2F6,EPB41,HSPA12B,MED12L,FHL1,FOXO3,NBEA,RAB40B,HLF,CELF5,LRRCC1,MAN2A2,PPM1L,AFDN,MYCN,SFR1,PFKFB2,MINDY2,GRAMD1C,FAM184A,TRIM68,GTDC1,MEG3,PEAR1,CCDC88A,SIK3,TSC1,CCDC136,PLSCR4,ST7,KLHDC1" Coexpression M4521 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "CLK4,ARRB1,ATP1A1,CFAP410,CAPN3,RUNX1T1,ARHGEF1,ARHGAP33,SH2B1,ABCC5,MRNIP,PCOLCE2,RASGRP2,SH3YL1,USP21,SARAF,OGA,DENND2A,MALT1,STARD3,AP4S1,KCND1,MN1,MYH3,CDK18,CCSER2,VPS13C,DCUN1D2,ZNF671,RPS20,ATXN7,R3HDM2,FNBP1,MYCBP2,SST,CEP68,ASTN2,PDLIM2,CABIN1,TSC2,UBE2H,WNT7A,MARCH8" Coexpression M5299 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 40 h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "RALGAPA1,ASIC1,AMT,NCOA1,ATP6V0A1,CPS1,IPCEF1,DCAF4,RIPOR2,MYEF2,USP3,EEF1D,USPL1,RASGRP2,ADGRV1,FCGRT,FYB1,USP19,PPARGC1A,KCNH2,AFF1,MXI1,MYCN,PLCD1,PLIN1,PDZRN4,PTCH1,PTPRE,ZNF331,ATXN7,SGK1,PREX2,SLC8A1,TTC17,ZBTB43,MCF2L,ATMIN,PHF24,KAT6B,WNT7A,MARCH8,NLRP3,DPF3" Coexpression M9335 Genes down-regulated in follicular B cells versus those stimulated with anti-IgM and CD40 [GeneID=958] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "ASPHD1,ATP2B2,GPR146,UBE2L6,MYL6B,AKAP12,IPCEF1,GPRASP1,ARHGAP32,HDAC4,EARS2,ZNF804A,FBXL5,RPS6KL1,CDON,TSPAN5,CDKL3,TLR7,CHST15,SLC9B2,FGF13,SPECC1,HVCN1,GABBR1,INPP5K,IL6R,SYTL4,TMIE,LRP12,SLC26A11,RGS12,RNASEL,KIAA0895L,GALNT10,ATF7IP,IZUMO4,MYCBP2,TROVE2,STX1A,TNS1,STXBP4,SSBP2,PPP1R3F" Coexpression M9352 Genes down-regulated in follicular B lymphocytes versus marginal zone B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "LRCH2,APAF1,NCOA1,ATP1A3,ATP2B2,ATP6V0A1,SYNJ2,IL33,CA12,CALB1,VAX2,LY86,TOGARAM2,KIF26A,DYNC1I1,EDNRB,PHF20L1,MED12L,OLFM1,FGFR3,MEX3B,KHDRBS3,CGREF1,GABRG1,SRRM4,NEU3,DCLK2,ATOH8,SCIN,MEIS2,MID1,PCDH18,IRX1,ROBO2,SH3GL3,FBXO11,LIMS2,SSTR2,SIK3,XPO1,ANKS1B,AMN1,ST8SIA2" Coexpression M7901 Genes down-regulated in monocytes versus macrophages. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "PPP4R4,KALRN,SLC25A14,MYRIP,LRRC3B,DZIP3,GAPVD1,BRINP1,AIF1L,TIAM2,PLPPR4,RAB39B,EDIL3,MBNL2,C3orf18,PAN3,CDKL3,FOXO3,CSDC2,LNX1,GP1BB,GRIA2,HLF,KCNN2,SYTL4,LSAMP,ASPRV1,MAT2A,MEF2C,MMP16,MN1,LYRM9,NCAM2,PRKACB,PTPRE,MBD5,NMNAT2,UHRF1BP1L,MYCBP2,THSD1,SYN2,RGMB,XRCC4" Coexpression M7157 Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "ESYT2,SFMBT2,GPR146,BAIAP3,PPT2,HDAC4,PDCD6IP,EXTL2,POLR1B,FGF13,EVL,ERAP1,SEPT9,KCNMB4,PADI2,ZDHHC15,IL6R,IL6ST,ITPKB,SLC35G1,KIF2A,STXBP5,MBNL1,MBP,SRSF12,SLC11A2,SETD4,P2RX7,TMIE,PRKACB,EML5,CEP97,RGS3,RNASEL,TMLHE,ATP8B4,CLIP1,SCP2,GALNT10,PIK3R5,RUNDC3B,SSBP2,SPATA13" Coexpression M4994 Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "OSBPL8,APAF1,KIF1A,BTK,CDC25B,PREPL,DCAF4,IP6K1,EIF5,GMPR2,OLFM1,NOP56,PDLIM5,CBX1,SYNPO,TJAP1,IPO5,MBP,MEIS1,AFDN,FAM216A,PPP2R5E,RFX2,KLHL11,CCDC25,RPL15,RXRA,TRA2B,SLA,SMARCC2,USP33,SPATA7,ELOVL4,SEPT8,SYNE2,MMS19,SATB2,ZNF106,LAT2,ZFAND5,ZNF225,EPM2A,DPF3" Coexpression M6404 Genes down-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "PHYHD1,MAP4K4,ANKRD44,ABCG1,MYADM,CD99L2,RPS6KL1,NR1D2,EPB41L2,RASGRP2,SLC43A2,MRPL10,TLR7,FGF13,PDLIM5,SARAF,TUBGCP4,FUT10,STON1,PDE4A,GNG2,NLGN3,PIK3C2A,MINDY2,SUSD4,SEMA6D,SGK1,ANKRD6,SLC9A5,ABTB1,CDK19,SS18,ST5,SYP,DNMBP,TP53BP2,NDRG4,MKRN3,SH3GLB2,PLSCR4,JMJD1C,ZDHHC20,SNX14" Coexpression M9260 Genes down-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5+ BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "GPR146,LDLRAD4,CCNT1,ZMYM4,CFL2,MAP4K4,COL11A2,ZFP28,ABCG1,PHF14,NR1D2,EGR3,CHST15,SUCO,ZMAT1,RAPGEF6,SPIN1,ATE1,HECTD2,NFIX,NUCB2,PDE4B,MINDY2,PSD,CLIP1,ZNF354C,ST8SIA1,ZFP1,ZNF667,TMCC1,ERBIN,SULF2,ALG1,TBCEL,TCF12,THRA,R3HDM1,TRIO,RUNDC3B,SSBP2,TTC3,MPPE1,JMJD1C" Coexpression M9269 Genes up-regulated in spleen B lymphocytes versus bone marrow plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "NDRG2,ADCY6,TMCC3,SORCS2,OSBPL8,AMPD3,SEMA4G,RASL11B,TMEM108,BTK,CACNA2D2,FOXN3,MYL6B,KIAA0040,DAPK1,GUCD1,FRY,EGR3,TMEM35A,CALCRL,EPB41L2,RASGRP2,ZNF605,GSN,BACH2,STMN1,HECTD2,SRSF12,MX1,MYO6,TMIE,MINDY2,BEND5,ZDHHC14,EMID1,GALNT10,TET1,TNS1,TTC3,TUBB2A,SGK3,UBE3A,FRMD6" Coexpression M9262 Genes down-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5- BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-05 1.95E-01 6.46E-04 6.41E-03 43 200 "ACTN1,ADCY6,SORCS2,OSBPL8,SFMBT2,TMEM108,GPR146,MTMR2,CNN3,RIPOR2,DAPK1,HIPK3,RASGRP1,MBNL2,EGR3,CALCRL,CHST15,SESN1,KCNMB4,GPD2,BACH2,IL6ST,AFF1,MYO6,NFIX,NUCB2,PDE4B,PPM1B,PTK2,RASGRF2,BEND5,SATB1,ST8SIA1,ATF7IP,TET1,SULF2,ZEB1,TNS1,TTC3,UBE3A,ZNF24,REEP1,PPP1R3F" Coexpression 20003503-SuppTable1 Mouse Lung_Moulos09_925genes GeneSigDB 1.78E-05 2.02E-01 6.68E-04 6.63E-03 110 668 "ADCY6,PWWP2A,ESYT2,HECW2,TBC1D14,AMPD3,OGT,PHF12,FAM131A,NCOA1,KIF1A,BARD1,GPR146,DST,CAMK2G,CARS,P2RX6,SCARB1,SLIT2,ENTPD4,ABCG1,OSBPL3,PHF14,DOCK4,LONRF1,DAPK3,DBI,PITPNC1,ZBTB24,EXOG,RAB39B,DRP2,AASDH,KLHL5,YAF2,SUGP2,EIF4G2,EIF5,ING4,PCOLCE2,GPHN,SRRM1,GMPR2,NRN1,FAM198B,ACSL4,POLR1B,VTI1B,TMEM107,PDLIM5,CELF1,SARAF,TPPP3,DENND2A,PSIP1,HAS2,NCKAP1L,DDX19B,ATXN2L,GATD1,SFXN5,HECTD2,MAT2A,N6AMT1,PAX6,PDE4A,ENPP2,SMOX,LRP12,POU6F1,PPM1B,PPP5C,CEP41,NDUFS7,CEP97,RBBP6,KHDRBS2,RDX,GTDC1,LGI2,RMI1,SALL1,TRA2B,COPZ1,HSPA4L,LIMS2,WDR47,SEPHS1,NAPB,SMARCA4,OGDHL,SMARCD3,SPATA7,GLT8D1,KDM4C,SEPT8,PRRC2C,SMG6,ATMIN,CLASP1,WBP2,TSN,TFIP11,ZFAND5,UPF3A,MPPE1,FAM13C,UBE3B,RNF170,SOCS4" Coexpression 19351829-SuppTableA Human Lung_Daniel09_314genes GeneSigDB 1.79E-05 2.03E-01 6.71E-04 6.65E-03 57 292 "RALGAPA1,AS3MT,EMILIN3,PLEKHH1,PKP4,N4BP2L1,CFLAR,MTMR3,MTMR2,CARS,CLCN3,COL9A3,MAGED1,ABI3BP,RCHY1,CTH,ARHGEF4,ARMCX4,KIF19,HIPK3,MBNL2,SRPK3,PAN3,FDFT1,FGF12,FGFR3,MSANTD4,NTNG2,GPT2,GPD2,ELOVL5,HMGCR,STXBP5,MAP4,MYO7A,NACA,HNRNPM,NF1,TRHDE,PSAT1,SDK2,DRAM2,DEF8,CNTLN,RAP1GDS1,ROBO1,AP1AR,SARS,BTBD3,ABTB1,PDZD2,RHBDL3,CDH22,RELL2,CABIN1,KCNK12,NETO2" Coexpression M7632 Genes down-regulated in CD8 T cells: naïve versus 2' memory. MSigDB C7: Immunologic Signatures (v6.0) 1.80E-05 2.05E-01 6.73E-04 6.67E-03 38 169 "PTCHD1,OSBPL8,OGT,MAP4K3,ZFYVE28,CACNA1A,SPAG9,PPT2,COX4I1,GSDME,NR1D2,MBNL2,PLXNC1,PTK2B,SEMA4D,DOT1L,MPP6,GPR162,STARD3,IGF1,IL6ST,STXBP5,L1CAM,TTYH2,MOV10,MX1,PTPRO,CYB561D1,FNIP1,SLC6A8,CPEB4,MYCBP2,NFASC,ITPRID2,ANKRD12,TPCN2,SYNE1,PARP11" Coexpression M2129 Genes up-regulated in confluent IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-05 2.09E-01 6.84E-04 6.78E-03 96 566 "AS3MT,C3orf14,ADD1,BEND6,MTUS1,OSBPL1A,VAT1L,SHROOM2,ARRB1,JAZF1,RUNX1T1,CBS,CHN1,NRXN3,CNN3,ABI3BP,FAM171B,CLIP3,OSBPL3,RASSF2,PLPPR4,EXOG,MAMLD1,TSPAN5,TMTC1,FRY,OPTN,RGS17,TMEM35A,EPB41L2,LRRC17,MRVI1,FAM198B,TUBA1B,TUBB3,PRKAG2,SCARA3,EVL,GALNT15,MTHFD2,RAB40B,GSN,FRMD5,ACOT7,SYNPO,ICA1,IFI16,FAM69A,KCNH2,KCNN2,MATN2,MEST,MN1,NFIX,NPTX1,CLDN11,OXTR,CNTN3,NALCN,PKM,PMP22,PSAT1,MINDY2,RELN,PTCH1,ELOVL2,PTN,PTX3,RAP1GDS1,UBR7,BAALC,SARS,SCN7A,TNFRSF19,PEAR1,GALNT10,SHMT2,FHOD3,LIMS2,SLC14A1,DOK5,MPRIP,SYT1,MTCL1,KIAA0930,C18orf54,TPM1,TPM2,RGMB,SYNPO2,TUBB2A,ATP6V0E2,TUBA1A,NAV3,MSRB3,DPF3" Coexpression M10117 Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [GeneID=4869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.88E-05 2.14E-01 6.98E-04 6.93E-03 50 246 "PROM1,WASF1,BAIAP3,LDLRAD4,THSD7A,RUNX1T1,CD38,CACNA2D2,B4GALT6,C2CD2,CLIP3,PPP1R16B,SCRN1,DPYSL2,OPTN,FGF13,FGFR1,FHL1,EVL,GALC,GATM,HPGDS,GSN,IFI16,KIT,TM6SF1,MEF2C,MEST,MN1,MX1,NBL1,PALM,PDE4B,CYTL1,ABCB1,GPSM2,PRODH,ROBO1,BAALC,RPS6KA2,STK32B,MEG3,SNCA,AGTPBP1,KCNE5,SSBP2,VLDLR,LAMP5,SLC38A1,ITM2C" Coexpression M2535 The '3/3 signature': genes consistently down-regulated in all three pools of normal mammary stem cells (defined by their ability to retain the dye PKH26). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.93E-05 2.20E-01 7.15E-04 7.09E-03 34 145 "AK2,IGDCC4,CA12,CALM1,ARHGEF2,CHN1,CNOT8,ARMC8,VCAN,GPRASP1,ARHGAP32,DNM1,EBF1,RGS17,STX2,FHL1,GABBR1,TNRC6A,GUCY1B1,KITLG,ZNF862,GNG2,PCDH18,TUG1,NCBP3,CHD9,TROVE2,PCDHB10,PUM2,HEY1,TRIO,RUSC1,JMJD1C,RNF146" Coexpression 12471243-TableS2 Human Manning02_624genes_ProteinKinases GeneSigDB 1.97E-05 2.24E-01 7.26E-04 7.20E-03 68 368 "CLK4,ALK,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,BTK,DDR1,CAMK2A,CAMK2B,NUMBL,MAP4K4,DAPK1,DAPK3,HIPK3,EGFR,IRAK4,TNK2,SPEG,CDKL3,RPS6KC1,PTK2B,STRADA,FER,FGFR1,FGFR3,FLT1,CAMKK2,BRSK1,FYN,GCK,TTBK1,CIT,MAP4K5,IRAK3,MYLK2,JAK2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,KSR2,CDK18,PKD1,MAPK3,MAPK9,MAPK10,SNRK,RET,RNASEL,NEK11,RPS6KA2,LRRK2,HUNK,SGK1,MAST1,NEK4,TTBK2,TEK,TRIO,SGK3" Coexpression M6516 Genes down-regulated in epithelial cells (6h): untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 2.04E-05 2.32E-01 7.49E-04 7.43E-03 42 195 "ACTN1,MTA3,AP2A2,AK2,ARRB1,N4BP2L1,NOG,CNN3,NSL1,KIAA0040,ARHGAP32,ZFYVE16,SCRN1,AASDH,ANKRD46,C8orf37,RASGRP2,SLC43A2,ARMCX1,NBEA,MPP6,GABBR1,RAPGEF6,PRDM5,ZC3H12B,NRCAM,NUCB2,ETFRF1,TMOD2,PLCL1,SDK2,GAL3ST4,PGBD4,PTGR2,ZFP2,SPART,ELOVL4,PJA1,TRIM2,SSBP2,TOM1L2,ZNF711" Coexpression M8239 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells treated by digoxin [PubChem=2724385]: wildtype versus RORC [GeneID=6097] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.07E-05 2.36E-01 7.60E-04 7.53E-03 38 170 "RALGAPA1,TAOK1,USP37,ATP2A2,DOCK11,BARD1,CDC25B,MAP4K4,NCOR1,SIPA1L1,PITPNC1,CNNM1,CORO2B,MED12L,SLC37A3,SMC2,IQGAP2,KAT7,TOX2,NF1,PKM,VPS13C,PPM1E,FNDC3A,ST8SIA1,ATF7IP,ZHX3,UHRF1BP1L,ERC1,TBCEL,ZEB1,RPGRIP1L,FRYL,ZNF106,TSC2,WRN,PRDM10,DOCK8" Coexpression M1311 Genes down-regulated in cancer endometrium samples compared to the normal endometrium. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.10E-05 2.39E-01 7.65E-04 7.59E-03 23 82 "SRPX,LTBP4,RUNX1T1,LDB2,CNRIP1,KIF26A,DPP6,ECM2,EDNRB,TMEM132C,OLFM1,MASP1,PID1,RORB,MEG3,SIN3B,ZEB1,SYNPO2,TRO,FLRT2,PLEKHH2,MICU3,TCEAL7" Coexpression M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.10E-05 2.39E-01 7.65E-04 7.59E-03 81 460 "ACTN1,FMNL2,SRPX,BIN1,RGS20,RNF182,BACH1,BCHE,MTMR2,SPAG9,CFL2,SLIT2,QKI,MAP4K4,CNRIP1,NECTIN3,AKAP12,GSDME,SACS,DMD,DNM1,EDIL3,EGFR,EPB41L2,STX2,EXTL2,KATNAL1,CORO2B,FER,FHL1,FOXF2,FLNC,MALT1,HAS2,TOX2,IGFBPL1,IFI16,INPP1,FAM69A,IPO5,SMAD9,MID1,LAYN,PDE4A,GNG2,PMP22,SH3KBP1,SPDL1,PTPRG,PTX3,FAT4,RGS4,CCDC82,KIRREL1,SGK1,FHOD3,DZIP1,ARHGEF40,CCDC88A,NMNAT2,MIR100HG,ITPRID2,MPRIP,ANKRD28,MTCL1,NR2F1-AS1,ZEB1,FAM200B,GPR161,TPM1,ELP5,TRIO,FLRT2,WIPF1,CLIP2,ZIC2,DHX33,NAV3,ITM2C,RTN4,MSRB3" Coexpression M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.18E-05 2.48E-01 7.92E-04 7.85E-03 71 390 "SYN3,ADORA2A,ADGRF5,SRPX,IGDCC4,RGS11,NRP2,CALM1,CH25H,CDC25B,CFL2,CNN3,WHRN,ABI3BP,CNRIP1,AKAP12,LRIG1,PPP1R16B,CYBB,MYADM,DOCK2,DPYSL2,ECM2,EBF1,EDIL3,EDNRA,HEYL,TMTC1,EBI3,ELN,EPB41L2,RCAN2,ETV1,NRN1,AMOTL2,FHL1,FOLR2,FYB1,FYN,IQGAP2,MALT1,GSN,GUCY1A1,HLF,SYNPO,LIG4,AFF1,MYO5A,PMP22,SH3KBP1,MAPK7,PTK2,C1orf54,SEMA6D,STUM,ST6GAL1,CMTR2,PDZRN3,SAMSN1,RGL1,TACC1,TCF4,FAM200B,TNS1,TPM1,TPM2,LAT2,ZFAND5,ADAMTS9,PHTF2,TTC7A" Coexpression 16140871-Table1 Human Leukemia_Toren05_133genes GeneSigDB 2.25E-05 2.56E-01 8.16E-04 8.09E-03 26 99 "PROM1,CLGN,B4GALT6,ARHGAP22,CRHBP,EXTL2,FHL1,ADAM28,GUCY1A1,HLF,KIT,MEIS1,MEST,MYCN,NPTX2,SCHIP1,NUDT11,BAALC,ANKRD6,BTBD3,PDZD2,THSD1,SSBP2,NPDC1,ITM2C,PLSCR4" Coexpression M16009 Genes whose DNA is hyper-methylated in hepatocellular carcinoma (HCC) compared to normal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.28E-05 2.59E-01 8.21E-04 8.14E-03 145 935 "ASIC1,ADD1,UNC5A,KIAA1211,SLC24A4,TXNDC16,C1QTNF1,ADGRF5,ANK2,C6orf89,KCNAB2,KIF1A,BMPR1B,CACNA1B,KALRN,RUNX1T1,CD86,ZMYM4,DLGAP2,ARHGAP22,TMEM184B,CNGA3,FHL5,CNR1,COL9A1,RGS6,CSF2RA,ARHGEF10,PDE4DIP,CST3,PLXNA4,RASGEF1C,FAM131B,GAPVD1,RIPOR2,ARHGAP24,DGKB,DGKG,TMEM170A,DBI,ZNF804A,TIAM2,SV2B,TMCC2,DLX1,DMD,DPP6,E2F6,TSPAN5,IRAK4,TENM1,ADGRV1,FCGR1A,FCGR1B,FGF1,FOXO3,ST6GALNAC3,MSANTD4,FYB1,FYN,DISC1,CPLX2,SULT1C4,MALT1,LYVE1,NTNG2,GLI2,GPR12,ADAMTS13,GRM8,GUCY1A1,NCKAP1L,MIER3,IGFBPL1,KIAA1755,SCIN,STXBP5,TTYH2,SMAD9,MATN2,ADAM11,MEST,ZNF92,HS6ST3,MYO5A,MYO9A,NEFM,JAKMIP1,PDZRN4,PPP2R2C,PKIA,GRAMD1C,DIRAS2,DCHS2,VPS13C,TMEM104,PTPRE,PTPRN2,ACSS3,CRTAC1,ARMC5,GSTCD,KIRREL1,EPHA10,FBXW7,STK32B,PTGR2,ABCA11P,SEMA6D,SCP2,FRMPD1,HKDC1,AMBRA1,FHOD3,NBPF1,SLC6A8,SLC8A1,RADIL,ATF7IP,TET1,GKAP1,DMRTC1,LIMCH1,PDZRN3,DOP1A,NFASC,CLASP2,CLSTN2,POGZ,ASTN2,CAMTA1,NEU4,PCDHGA2,HIF3A,ZFPM2,RASD2,TST,CCDC136,VIPR2,MKRN3,SPIRE1,MDH1B,WNK2,KAT6A,NLRP3" Coexpression M10575 Genes exclusively down-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071] after high dose UVC irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.34E-05 2.66E-01 8.41E-04 8.34E-03 24 88 "APBB2,DST,CDH2,SLIT2,NECTIN3,ARHGEF10,PHF14,DOCK4,E2F5,VPS13B,PDLIM5,ATP2C1,AHDC1,MALT1,AGFG1,PIK3C2A,PTX3,WDR37,TMCC1,DOCK9,FAM155A,VLDLR,INTS3,NAV3" Coexpression 15558013-FigureS1b Human HeadandNeck_O?Donnell05_93genes GeneSigDB 2.48E-05 2.82E-01 8.90E-04 8.83E-03 21 72 "ADCY8,PTCH2,N4BP2L1,KSR1,ARHGEF7,CACNB4,ARHGAP33,ERBB4,CORO2B,FGF1,GABRB3,DENND2A,NXPH3,KCNJ5,MYO7A,NNAT,PKD1,CNNM2,THSD1,PCDHB6,PIK3R5" Coexpression M7722 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 2.52E-05 2.87E-01 9.01E-04 8.93E-03 36 159 "FMNL2,SEMA7A,DPY19L3,PPT2,TMEM184B,LRIG1,PPP1R16B,DOCK2,SLC12A6,MBNL2,PAN3,USPL1,IP6K2,SEMA4D,AHDC1,DIDO1,GUCY1A1,SYNPO,MBNL1,MBP,NTRK3,PDPK1,PFKFB3,PRODH,EML5,FAM161B,SATB1,SLC9A5,ARFGAP1,TTC17,KDM4B,FNBP1,KDM4C,ARHGAP26,SUPT5H,PIK3R5" Coexpression M2809 Genes up-regulated in oligodendrocytes. MSigDB C6: Oncogenic Signatures (v6.0) 2.73E-05 3.10E-01 9.71E-04 9.63E-03 26 100 "LCORL,BCAS1,MYRF,HIP1R,FBXO7,GAL3ST1,CRYM,CNTNAP2,SEMA3D,SRPK3,SPEG,PRKAG2,CSDC2,ZNF276,KIAA1958,LRRC75A,NINJ2,FA2H,FIGN,MAP6D1,EPN2,SIRT2,ATP10B,PHLDB1,UGT8,WIPF1" Coexpression 18757322-TableS1 Human Breast_Creighton08_2154genes GeneSigDB 2.76E-05 3.14E-01 9.80E-04 9.72E-03 247 1739 "RALGAPA1,ACTN1,MTUS1,OSBPL1A,NME5,KIAA1324,AK2,BEGAIN,PKP4,APAF1,APBB2,APLP1,PPFIA3,CDC14B,CASK,ARNTL,ZBTB10,ALDH7A1,N4BP2L1,BCS1L,CFLAR,BMP7,FUBP1,RAB29,CA4,CA8,CAMK2B,CAMK2G,CAST,CARS,NFS1,PRC1,CBS,SCARB1,SYNGR3,ENTPD6,ARHGEF2,CDC25B,ARHGAP33,LARGE1,TBRG4,CLGN,RCBTB2,FOXN3,CNOT8,LHX2,CLCN3,TPP1,CLTB,QKI,HOMER3,IQCK,LETMD1,COL9A3,LRIG1,FAM169A,DZIP3,GREB1,DOCK4,ARHGAP32,TCAF1,TBC1D5,KIAA0586,IP6K1,DBI,GIT2,DBN1,ARMCX2,B3GAT3,MFAP3L,RHOBTB1,SACS,DMD,DNM1,DTNA,ABCC5,RASGRP1,FRY,OPTN,EGR3,RASA4,EIF5,ING4,PCOLCE2,EIF1,ERBB4,RRAGB,GMPR2,ARMCX1,SH3YL1,TUBA1B,TUBB3,CHST15,FDFT1,SEC24B,OLFM1,FGF13,TMEM164,FHL1,IP6K2,FOXO3,NOP56,NBEA,SMC2,TPK1,MPP6,OGA,FYN,GALC,INPP5K,BRD8,TCERG1,DBF4,TOX3,GLUL,RAB40B,ADGRA3,STON1,GPER1,GPR37,GRB10,DIDO1,GUCY1B1,MUM1,ACOT7,GABARAPL2,HMGCL,HMGCR,HNMT,IDH3A,IL6ST,KCNN2,L1CAM,LMO2,MAPT,MAT2A,MATN2,MEIS1,MIA2,MID1,MXI1,NELL2,NME4,NPR2,PCDH8,PFKFB3,PIK3R1,SNX10,RETREG1,GPSM2,NLE1,PLCL1,PMP22,RETREG2,PPP5C,PKIA,PRKAR1B,MAPK9,GRAMD1C,DIRAS2,NDUFS7,DEF8,PTCH1,ELOVL2,SPDL1,PTPN13,PTPRE,PEX2,NKAIN1,TTC13,ACSS3,SUSD4,MORC4,MRPS18A,NUDT11,DCUN1D2,EXD2,CARF,PCMTD2,NEK11,MAP6D1,RTN1,RXRA,SARS,PPM1E,FERMT1,SHMT2,R3HDM2,ABLIM3,SLC6A8,KBTBD4,ATF7IP,CXXC4,RCOR3,LMBRD1,PDZRN3,SOX3,SPATA7,KDM3A,GLT8D1,IQSEC2,CDK19,SPART,PBLD,ZNF302,CEP68,KANK1,KLHL7,JMJD6,ARHGEF9,DNAJC9,TACC1,TCEA1,KIAA0930,TRIM2,RPGRIP1L,PCDHAC2,PUM2,SIK3,SIRT1,TMEM121,AKTIP,CBX5,TMPO,BEX4,TPM1,PDSS1,RUNDC3B,TUBB2A,SGK3,UBE2H,VLDLR,TBC1D15,WIPF1,KLC2,ZNF32,ZNF74,RNF103,TUBA1A,CIAPIN1,PCBP4,PLSCR4,MARCH8,UBE3B,ACTR3B,FXR1,NETO2" Coexpression 19377508-SuppTable3 Human Lymphoma_Chin09_65genes GeneSigDB 2.78E-05 3.16E-01 9.83E-04 9.75E-03 16 47 "ABR,MAP4K3,BMP7,CCNH,CD86,CD38,BACH2,ITPKB,KCNN3,LMO2,OGG1,PCDHGC3,RASGEF1B,PRKACB,PTK2,WIPF1" Coexpression M10311 "Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 6 h time point that were not down-regulated at the previous time point, 4 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.91E-05 3.31E-01 1.03E-03 1.02E-02 36 160 "BACH1,CFLAR,ARHGEF2,HDAC9,YTHDC1,ZBTB24,FBXL5,DMTF1,FRY,EPB41,ETV1,AMOTL2,STAU2,ZNF44,GLI2,STON1,GRM8,ICA1,ITGAM,SMAD1,MEIS1,MN1,PIK3R1,SCHIP1,PCMTD2,RPE,SCAF8,SGK1,SLC22A4,DOP1A,TROVE2,CEP68,KANK1,ANKRD28,TRIM2,ZNF24" Coexpression M1796 The glioblastoma multiforme (GBM) plasticity signature: genes up-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.94E-05 3.34E-01 1.04E-03 1.03E-02 50 250 "SPARCL1,APLP1,VAT1L,BCAS1,TMEFF1,BMPR1B,RAB29,VXN,PRC1,CD38,LRRFIP1,CRLF1,RAB33A,ZFP28,CSF2RA,CHRDL1,EDNRB,TUBB3,SPSB4,SMC2,CHL1,MTHFD2,CPLX2,ALDH1L1,CSDC2,DBF4,GNAO1,GPD1,GPD2,CIT,ACOT7,MBP,TAGLN3,NRCAM,CLDN11,SDK2,PPP2R2B,PRKAR1B,PSD,PTPRD,TMLHE,ROBO2,SLC6A11,SPP1,TRIM2,TIMP4,UGT8,USP1,WNT7A,CADM2" Coexpression M8161 Genes up-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 2.99E-05 3.39E-01 1.04E-03 1.03E-02 42 198 "RALGAPA1,NME5,PARG,APOC1,APOC2,ADGRB2,BAIAP3,THSD7A,USP2,CDH2,DCLK1,LOC730101,FHL5,OSBPL3,SPATA2,PLEKHA1,VPS13B,ERBB2,EZH1,ARMCX1,DENND2A,NCAM2,NELL2,OGG1,OPA1,MARCH1,RAD17,SEMA6D,CCDC92,PREX2,SOX3,SOX11,TSPYL2,PJA1,MCF2L,FAM208A,FBXW11,TEK,SPHK2,ZNF154,ZSCAN26,JPH3" Coexpression M5424 Genes up-regulated in comparison of eosinophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 2.99E-05 3.39E-01 1.04E-03 1.03E-02 42 198 "ARRB1,CACNA1G,CALM1,LRRFIP1,DLGAP1,CLOCK,CLIP3,PITPNM3,TBC1D5,MAML1,GIT2,DBT,PLXNC1,EIF1,CHST15,GCNT2,USP19,GRB10,SOX21,PACSIN2,ELOVL5,HSPA1L,INPP5B,KIT,LAMP2,SHC3,MID1,NFE2L2,ZSCAN32,PTPRE,SMPD3,CPEB3,WDR37,MAST1,SYNE2,SYT1,CAMTA1,PCDHGA10,ZNF34,UGT8,ZFAND5,NAV3" Coexpression M8400 Genes down-regulated in brain microglia versus spleen CD8- dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.99E-05 3.39E-01 1.04E-03 1.03E-02 42 198 "ACHE,ADD2,AP2A2,ABCD2,PPFIA3,CDC14B,PLA2G4C,ADGRB1,RCBTB2,NRXN3,CNTFR,GREB1,CYBB,DMD,DNAH9,AASS,FLT1,CRCP,RAB30,GPER1,KAT7,KCND1,KCNJ5,KCNN1,L1CAM,LAMA2,SMAD9,PCDH9,IQSEC3,RGS4,RGS12,SCN7A,PPM1E,FNDC3A,SLC6A8,SLC12A4,SP4,MCF2L,CDH22,THRA,VSNL1,SLC30A3" Coexpression M14573 "Set 'NOS targets': genes upregulated and identified by ChIP on chip as targets of the transcription factors NANOG , OCT4, and Sox2 [GeneID=79923;5460;6657] (NOS) in human embryonic stem cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.01E-05 3.42E-01 1.05E-03 1.04E-02 39 179 "PARG,CDC14B,BMP7,CA4,CACNA2D1,SPAG9,LARGE1,TMEM170A,MED12,DPYSL2,DTNA,AASDH,KLHL5,PIPOX,FGFR1,UFM1,OGA,TNRC6A,LINGO1,HAS2,IFI16,KCNN2,ENPP2,RASGRF2,RIC8B,SALL1,SNRPN,KDM3A,LHPP,KANK1,TAL1,FBXW11,OBSL1,SLC44A1,ZIC1,ZIC2,SMARCAD1,URM1,KAT6A" Coexpression M3654 Genes up-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.04E-05 3.45E-01 1.05E-03 1.04E-02 75 422 "ZNF608,APBB2,ARHGDIA,ARNTL,RASL11B,IL33,PTBP2,CNOT8,TPP1,CNN3,PREPL,RNF14,VCAN,PPP1R16B,ARHGAP24,MATR3,DOCK2,EDN1,MBNL2,CALCRL,EIF1,ETV1,TLR7,FAM198B,ST3GAL6,FGF1,SCARA3,FOLR2,ERAP1,ARFIP1,HPGDS,HTATSF1,GPR34,LINC01089,GSN,FRMD5,PACSIN2,MIER3,VSIG4,HNMT,IRF8,JAK2,PAXBP1,MAT2A,MSR1,P2RY13,SFR1,NTRK3,ENPP2,MINDY2,TATDN3,PTK2,RDX,GTDC1,RGS4,RNASE1,ST6GAL1,SLC8A1,SLC11A1,SS18,NECAB1,ARHGEF9,SYPL1,ANKRD12,FBXW11,ZEB1,TLR4,UCHL1,VSNL1,RICTOR,ZNF540,SPIRE1,ZFAND5,PLSCR4,NHSL1" Coexpression M828 Genes down-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.06E-05 3.48E-01 1.06E-03 1.05E-02 51 257 "APBB2,ZBTB10,WASF1,CA12,CALB2,SCARB1,LONRF2,LARGE1,COL4A5,LRIG1,GREB1,RHOBTB1,EGR3,DLC1,OLFM1,TMEM164,FOXO3,GPER1,ARHGAP36,ELOVL5,HNMT,LAMP2,SYTL4,MAP2,MAPT,NRCAM,GPR173,PIK3R1,MBOAT7,APTX,ELOVL2,PTPRG,SUSD4,RBBP8,ELP2,RXRA,SH3BGR,SYBU,NBPF1,MYO16,KDM4B,SOX3,TSPYL2,SYT1,PCDHGA4,TIAM1,CBX5,NEIL2,TST,SGK3,MAP3K12" Coexpression M13809 Genes up-regulated in the samples with intrahepatic metastatic hepatocellular carcinoma (HCC) vs primary HCC. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.10E-05 3.53E-01 1.07E-03 1.06E-02 91 537 "C3orf14,PKP4,CDK13,BARD1,MTMR2,CA12,ARHGEF1,CBFA2T2,ARHGEF2,NUMBL,CLTB,MAP4K4,COL11A2,FAM171B,SH2B1,CSNK1E,VCAN,DBN1,MYEF2,B3GAT3,RHOBTB1,SLC29A4,DTNA,DUSP9,DNM1L,PLXNC1,ENO2,MFSD10,RACK1,GORAB,SYNCRIP,EFCAB2,ZNF234,MTHFD2,SEPT9,TOX3,MAP7D2,GNG4,PRRC2B,SLC2A6,PACSIN2,ATXN2L,KCNH2,KIF2A,MAP2,MAP4,MBNL1,SCAMP5,NACA,NRCAM,ZNF827,PCSK5,PDCD2,PFKFB4,OLA1,PKM,SMOX,MAPK3,VPS13C,SUSD4,FIGN,SLC25A36,ZNF532,C12orf49,ROBO1,GLDN,HUNK,FERMT1,HKDC1,FHOD3,SLC6A8,ARFGAP1,SNAP25,SNRPN,TMCC1,ZNF302,PLCB1,MTCL1,C18orf54,CBX5,TPM2,TRPS1,SSBP2,TUBB2A,UCHL1,ZIC2,ZFP41,TMEM237,STOX2,NAV3,NETO2" Coexpression M8124 Genes up-regulated in basal subtype of breast cancer samles. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.11E-05 3.54E-01 1.07E-03 1.06E-02 106 647 "ACTN1,NDRG2,ADD2,FZD9,AK2,BBOX1,APBA2,LGR5,TMEFF1,RGS20,DNAH17,KIF1A,PROM1,MTMR2,CACNA1A,CALB2,CBS,CLDN10,CD38,CDH2,CRLF1,PLEKHB1,LHX2,QKI,HOMER3,CNN3,COL9A3,COL11A2,HAPLN1,SUSD5,DBN1,HEPH,LYPD1,TMCC2,DYNC1I1,RCAN1,DUSP9,EDN1,EGFR,PCOLCE2,ELN,EPB41L2,NCALD,ST3GAL6,UBE2E3,SYNCRIP,IQCG,FOLH1,KHDRBS3,FUT9,MPP6,DENND2A,TXNL4A,GPR37,FAM107A,SLC2A6,PADI2,AGBL5,IFI16,ITPKB,KIT,L1CAM,MAP2,MID1,NEFH,NFIX,NPTX2,PAX6,GPSM2,LRP12,PSAT1,SCHIP1,KLK6,PTX3,NUDT11,ZNF532,KIRREL1,TCP11L1,S100B,MRAS,TRA2B,HSPA4L,PPM1E,FERMT1,DZIP1,ST8SIA1,CCDC88A,INAVA,SOX11,SOX15,SPP1,PEG10,ELOVL4,KLHL7,ARHGEF9,TRIM2,PCDHB3,GPR161,TPM2,TSN,UCHL1,UGT8,VLDLR,ZIC1,ITM2C,HRASLS" Coexpression M7184 Genes up-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.23E-05 3.67E-01 1.11E-03 1.10E-02 10 21 "ADGRB1,ADGRB2,CRMP1,CSPG5,DLL3,GRIA2,MAP2,SHC3,HES6,ADGRL3" Coexpression 18006812-TableS4 Human Lymphoma_Piccaluga07_89genes GeneSigDB 3.37E-05 3.82E-01 1.13E-03 1.12E-02 20 68 "ACHE,C1QTNF1,IGDCC4,C2CD2,SNCAIP,PLCXD3,SNAP91,DNM1,ARRDC4,EDN1,EDNRB,OLFM1,FGF11,FOXF2,ABLIM2,GATM,LIFR,MCF2L,TNS2,TNS1" Coexpression M4643 Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus adult regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "LCORL,PKP4,CACNA1I,KALRN,CAPN3,SPAG9,ABCG1,RIPOR2,NR1D2,AASS,ENO2,MTSS1L,CEP85L,SEMA4D,C2orf88,SARAF,OGA,ZNF782,COQ10A,LINC01550,IL6R,KIF5A,LINC00672,DPY19L2P2,PIK3C2A,POU6F1,TATDN3,PTCH1,RADX,MORC4,ZNF532,TRAPPC13,KIF21A,SPTAN1,ATMIN,SIRT1,PRRT1,RUNDC3B,DCBLD1,BCL2L13,ANKS1B,KAT6A" Coexpression M6567 Genes down-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus rosiglitazone and AM580 [PubChem=77999;2126]. MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "ADCY6,ADD1,PHYHD1,TMEFF1,MYOM1,CAMK2A,CLDN10,CD86,ARHGEF1,RCBTB2,COL11A2,ANKRD44,GUCD1,NYAP1,SEZ6L2,RASGRP1,DENND4A,MRVI1,TBC1D16,FCGRT,ZNF274,TPPP,GUCY1A1,DDX19B,SRSF12,PDE1B,PIK3R1,C19orf57,PPM1B,RIPOR1,RASGRF2,CCDC82,DGLUCY,GALNT10,RASA3,NMNAT2,POGZ,STX1A,CAMTA1,ARHGAP9,SMUG1,FRMD6" Coexpression M8143 Genes down-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "NME5,APOC1,ATP2A2,ADGRB2,ARHGEF7,THSD7A,CDH2,CDO1,FAM189A2,FHL5,COL4A5,COX4I1,CSF1,ZNF337,SPATA2,JAKMIP2,ECM2,VPS13B,PIPOX,FDFT1,DENND2A,GAD1,BTN2A1,SLC2A6,LSS,NCAM2,OGG1,OPA1,RGS12,SEMA6D,PREX2,KDM4B,PRRC2C,FAM208A,FBXW11,TEK,SPHK2,TFIP11,ADAMTS9,PHTF2,GJC2,JPH3" Coexpression M9994 Genes up-regulated during primary acute viral infection: B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "PTCHD1,BIN1,PKP4,EIF4G3,BCS1L,SEPT7,FOXN3,HECTD1,NCOR1,SCRN1,DBI,LYPD1,PLPPR4,FARSB,EDNRB,EEF1D,GPHN,PSMA3-AS1,RACK1,POLR1B,FGF13,GHR,GPD2,UBE2QL1,MSL1,INPP1,MARK3,SAMD5,NFE2L2,RETREG2,SAMD9,FIGN,RTN1,BTBD7,KDM3A,CLASP1,METTL3,TSN,PCDH20,ZNF142,TMEM237,MFF" Coexpression M8730 Genes up-regulated in T cells stimulated by IL2 [GeneID=3558] for 2h: STAT5 double knock-in versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "ACADM,OSBPL1A,SPOP,APOC1,CAPN3,CHN2,LY86,CNRIP1,CRHBP,OSBPL3,NR1D2,ABCC5,SNX29,MRO,TLR7,FECH,PCYOX1,TPK1,SARAF,IQGAP2,SESN1,GGTA1P,SPIN1,STMN1,NCOA7,MEF2C,MKLN1,MXI1,TREM2,GDPD1,VPS13C,RPS6KA2,DGLUCY,SGK1,FNDC3A,CDK5RAP3,SULF2,PLCB1,FAM208A,CCDC14,MPPE1,RNF170" Coexpression M4828 Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 3.38E-05 3.84E-01 1.13E-03 1.12E-02 42 199 "GAS7,SEMA4G,ARRB1,CHRD,RNF182,CA12,PRC1,AKAP7,NECTIN3,TRIM69,VCAN,RIMS4,FAM169A,UBXN2A,DNAL1,MYEF2,DNM1,ARRDC4,ERBB4,USP21,GALNT15,MAP4K5,NXPH3,AGBL5,IGFBPL1,KCNB1,KCND2,PAX6,TMOD2,STRN3,ARMH4,LRRK2,PLPPR3,KIF27,HSPA4L,LGI3,TNS2,SGK3,VSNL1,ZNF711,ZNF184,NAV3" Coexpression 20068109-SuppTable3 Human Breast_Horlings10_271genes GeneSigDB 3.52E-05 4.00E-01 1.18E-03 1.17E-02 49 245 "ZFAT,TNRC6C,DNAH17,CHRD,BCHE,PDE4DIP,FAM169A,PITPNC1,ABCC5,EBF1,PHF20L1,EIF4G1,VPS13B,ABCA8,ATP5PD,KHDRBS3,SYT17,SEPT9,KIAA1958,GRIN2D,HAS2,ZHX1,TTYH2,MATN2,GIT1,SERPINI1,PNMA3,LRP12,PPP2R5E,DEF8,TMEM104,MARCH1,SEC14L1,TRA2B,FAM102A,SYBU,NLGN1,SLA,ERBIN,JMJD6,SYN2,EXOC7,WBP2,TRPS1,FLRT2,EMX2OS,KCNAB1,MRPL47,FXR1" Coexpression M8928 Genes down-regulated in CD4 [GeneID=920] naïve versus Th17 enriched. MSigDB C7: Immunologic Signatures (v6.0) 3.58E-05 4.07E-01 1.19E-03 1.18E-02 38 174 "ADCY6,ZBTB10,CD38,CLTC,DAPK1,TOM1,DNM1L,EBF1,EIF5,TMEM35A,ACSL4,MPP6,GSTT2,ADAMTS6,ACOT7,TJAP1,IPO5,PIK3AP1,MYO9A,RETREG1,STRN3,PPP3CA,C1orf54,SLC25A36,ZC3H14,SLA,FNBP1,TEX2,SAMSN1,LARP4,ERBIN,SYPL1,TCF4,MTMR14,RUNDC3B,TUBB2A,PLD4,SENP7" Coexpression M4971 Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ACTN1,NDRG2,APAF1,GAS7,ARRB1,CD86,RCBTB2,LY86,C2CD2,CSF1R,VCAN,CST3,PLXNC1,EPB41L2,IGSF6,EVL,FYN,MTHFD2,ADAM28,IRAK3,PADI2,ELOVL5,RBPJ,LIMS1,P2RY13,NCF2,PILRA,PID1,RNH1,ATP8B4,RTN1,SEC14L1,SGK1,SH3BP2,AGTPBP1,TBL1X,NACC2,TRIO,TST,LAT2,TUBA1A,NLRP3" Coexpression M5692 Genes up-regulated in comparsion of ActTregTGF versus ActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "FMNL2,ARHGAP20,FAM131A,BCAS1,DYNLL1,RNF182,CD38,SLIT2,CNR1,HAPLN1,GDA,AATK,ARMCX2,DMD,FGF13,PRKAG2,KCNMB4,STON1,GUCY1B1,VSIG4,LRRC75A,LRRCC1,GPR62,KIT,GPR155,MEIS2,PPM1L,LAYN,GPR85,PPM1B,RGS12,ROBO1,HSPA4L,SLC12A2,SOX3,KIAA1107,TIAM1,ZFP41,ATP6V0E2,NDRG4,AMZ1,FRMD6" Coexpression M5620 "Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569] versus those treated with TGF3B [GeneID=7043], IL6 [GeneID=3569] and IL23A [GeneID=51561]." MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "AXIN2,GPRASP2,ZNF583,MTMR7,QKI,LRIG1,GAPVD1,PITPNC1,FBXL5,MBNL2,SLC9B2,ATP2C1,DLL3,SDCBP2,TUBA8,GFRA2,ATE1,GSN,NCKAP1L,MEIS2,NPTX1,ZDHHC8,PRKCB,PTCH1,RDX,RGS12,RIC8B,AP1AR,RASA3,SCAF8,FBXO11,ARHGEF40,BTBD7,ZFP1,SS18,STX1A,ZEB1,PIK3R5,UBE2H,TBC1D15,CADM2,RSPRY1" Coexpression M312 Genes down-regulated in primary bronchial epithelial cells stimulated with: IL17A [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "FMNL2,OSBPL1A,LRCH2,MAP4K3,PHF12,PDE8B,CCAR2,SCARB1,ARHGEF10,HDAC9,LONRF1,DAPK1,SV2B,SLC43A2,APC2,CHST15,DCLK2,KCNJ5,PPM1L,PTOV1,LAYN,PALM,NLGN3,PLCL1,CEP97,ELP2,ATXN2,SCN8A,KIF21A,LGI3,TET1,ZNF667,SMARCC2,IFT122,THSD1,TBCEL,TCF4,ZEB1,R3HDM1,UCHL1,FAM13C,NLRP3" Coexpression M5724 Genes down-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus untreated NK cells. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "AS3MT,ESYT2,CARNS1,CPNE5,MARCH3,ZBTB10,ATP6V0A1,CBLN1,AKAP5,CNRIP1,ABCG1,PHACTR3,RIPOR2,CPEB2,TMTC1,PLXNC1,NCALD,FOXO3,PSD2,ZNF274,ACSS1,GLUL,BACH2,MSR1,NRCAM,ABCB1,SERPINI1,PTH1R,IQSEC3,ZNF493,OXR1,PCMTD2,KCNIP3,ATXN7,TET1,SMARCD3,USP33,FAM219A,SYNE1,CCDC173,TRPS1,RICTOR" Coexpression M9130 Genes down-regulated in T reg: IKZF4 [GeneID=64375] versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ABHD6,RNF157,MTA3,PITPNM2,TNRC6C,CPNE5,CDK13,NCOA1,LY86,SIPA1L1,TBC1D5,GIT2,PITPNC1,ELMSAN1,DMPK,WDPCP,OPTN,PAN3,ANKFY1,ZBED3,STAU2,ATE1,GSN,BACH2,LRRC75A,LRRCC1,PRKCB,CNTLN,PTK2,REV3L,EPC1,GKAP1,ZBTB43,MPRIP,ADHFE1,STXBP1,CAMTA1,FAM208A,KIAA1107,KIAA0930,ZBTB14,TUBA1A" Coexpression M2719 Genes down-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH). MSigDB C6: Oncogenic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "RALGAPA1,UNC79,DYNLL1,DST,THSD7A,CALM1,SEPT7,LRRFIP1,FOXN3,MAP4K4,IQCK,AKAP12,ERC2,SPOCK2,DGCR5,TSPAN5,FRY,ENO2,SRRM1,TUBB3,CHST15,PCLO,LINC01089,UBE2QL1,BACH2,MAP2,NCF2,PFKFB4,PKIA,PTPRD,NUDT11,ANKRD6,PHLDB1,STXBP1,SYPL1,RASD2,UBTF,BCL2L13,NDRG4,PRDM8,GAL3ST3,SLC17A7" Coexpression M7607 Genes down-regulated in CD11b+ cells from BALB/c mice bearing: C26GM colon carcinoma versus 4T1 mammary carcinoma. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ABR,CLK4,ARHGEF1,CBFA2T2,SRSF11,FOXN3,ARHGEF6,MAML1,PITPNC1,PLEKHA1,USPL1,EPB41,POLR1B,EVL,MSL3,MSL1,MAN2A2,MXI1,LYRM9,ZNF862,NACA,CCSER2,PPM1B,WBP1L,SNRK,PTCH1,TMEM260,USP47,CASC3,TTC17,ANKRD36,SPTAN1,FAM208A,CLASP1,SYNE1,FRYL,DICER1,TSC2,TTC3,UBE2H,ZNF32,MPPE1" Coexpression M7472 Genes down-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "OSBPL1A,GPRASP2,CDC14B,SPTBN4,BACH1,LDHD,SGCE,SEC24C,PDE4DIP,DGKG,FRY,ENO2,MED12L,FGF11,FHL1,NBEA,MSANTD4,ALDH1L1,GHR,PPARGC1A,GLUL,ADGRA3,PRRC2B,FICD,ADAM22,MYCN,ZNF862,NPR2,OCRL,RASGEF1B,WBP1L,CASTOR1,OXR1,RNASEL,MPRIP,BHLHB9,STXBP4,TTC3,VLDLR,EMX2OS,PLSCR4,KLHDC1" Coexpression M5034 Genes up-regulated in comparison of SP2 thymocytes versus SP4 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ZNF608,WDR35,ARHGAP20,LRFN1,ANK2,FAM131A,ALDH7A1,EVI5L,CNN3,WHRN,BOC,TNK2,ELN,HSD17B14,DLC1,CEP78,FER,FGF12,UBE2E3,POMT1,GABRB3,TDRKH,GSN,ACOT7,KIFC3,MPP2,PCSK5,DUSP26,NALCN,PLXNB1,PTK2,MAPK12,ZNF821,ARX,SPTB,HIF3A,RPL7L1,CLEC2L,EMX2OS,TMEM237,TUBA1A,TMEM63C" Coexpression M5381 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "BIN1,N4BP2L1,BID,CALM1,DGKI,DCLK1,SEC31B,SH2B1,RIPOR2,MAML1,SGSM2,USP3,EDNRA,RASGRP1,OPTN,EIF1,ERBB2,EZH1,FOXO3,TRMO,TPK1,SESN1,BTN2A1,GSN,MBNL1,MYO6,RASGRF1,RYR3,KIF16B,R3HDM2,ST6GAL1,INAVA,DOP1A,SYNE2,CAMTA1,FAM208A,SIK3,KAT6B,TPM1,GDPD5,ZNF37BP,JMJD1C" Coexpression M7782 Genes down-regulated in memory CD8 T cells: wildtype versus TCF7 [GeneID=6932] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ACTN1,CCAR2,BCL7A,BLM,PRC1,AP4M1,LRWD1,EPS15L1,RTTN,CSF1R,RIPOR2,DCAF8,FAM107B,DLX1,DNAJB6,MRNIP,GPHN,TUBA1B,SLC37A3,GPR34,ELOVL5,ZDHHC15,LRRCC1,KIT,MN1,LYRM9,PPP3CA,PTK2,ZDHHC14,RTN1,DGLUCY,SEPHS1,MYCBP2,SPART,ANKRD28,PDLIM2,TMPO,RUNDC3B,AMACR,TTC3,MPPE1,SPATA13" Coexpression M6556 Genes down-regulated in monocyte-derived dendritic cells: untreated versus AM580 [PubChem=2126]. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "CARNS1,PHYHD1,STX16,BACH1,SCAPER,PCYT1B,SH2B1,CSNK1E,PDE4DIP,ARMCX2,MTX3,PRKAG2,ZNF274,MALT1,L1CAM,TTYH2,PAXBP1,GPR155,MAN2A2,MATK,MATN2,ZNF862,ZNF827,PIK3R1,PLCL1,ANKRD16,POLG,PTPN13,EML5,RFX3,CCDC82,PEAR1,ANKRD6,CEP68,DIP2A,STX1A,PJA1,TRIM2,TIAM1,TUBB2A,MICU3,FRMD6" Coexpression M9273 Genes up-regulated in germinal celter B lymphocytes: MYC- [GeneID=4609] versus MYC+ [GeneID=4609]. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ADCY6,TMCC3,SORCS2,PDZD4,MAP4K3,RASL11B,TMEM108,ST3GAL5,CNN3,KIAA0040,PHF14,DAPK1,EGR3,CHST15,FOXO3,KCNMB4,BACH2,IL6ST,STMN1,HECTD2,MYO6,PDE4B,PIK3C2A,TMIE,ZFYVE21,PTCH1,RASGRF2,BEND5,ZDHHC14,EMID1,ST8SIA1,TET1,TBCEL,TBL1X,TPCN2,R3HDM1,TNS1,SSBP2,TTC3,SGK3,PPP1R3F,FRMD6" Coexpression M5128 Genes down-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "OGT,BTK,DDR1,CH25H,ARHGEF1,ZMYM4,PPT2,QKI,HOMER3,MYADM,DPYSL2,PLEKHA1,SRRM1,FDFT1,SEMA4D,SMC2,USP21,B4GALNT1,TCERG1,HMGCR,ITGA7,PAXBP1,MAT2A,MOV10,SFR1,OGG1,ABCB1,PRKACB,PRKCB,RELN,CYBC1,PBRM1,RPL15,RTN1,KLHL7,SYPL1,TAF6,PUM2,ARHGAP9,LRRC8A,C9orf85,USP1" Coexpression M5819 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "CLK4,ACTN1,ADCY6,AMPD3,MAP4K3,CASK,ARRB1,CNN3,ABCG1,ARMCX2,ABCC5,PLEKHA1,RACK1,POLR1B,EVL,NOP56,SESN1,ZNF638,GSN,IL6R,IL6ST,ITPKB,KIT,SMAD1,PTOV1,SLC11A2,PKD1,RETREG1,EML5,SATB1,FAM102A,ST6GAL1,DHX30,MYCBP2,TBCEL,TCF4,ZEB1,SLC44A1,SSBP2,TTC3,RPL7L1,PHTF2" Coexpression M3440 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ACTN1,AGT,OSBPL8,PLA2G4C,ADAM23,ST3GAL5,RAB29,CACNA2D2,ARHGEF6,RASSF2,SPOCK2,TENM1,PLEKHA1,RASGRP2,NCALD,ZNF589,TPK1,SARAF,GRB10,BACH2,IL6R,IL6ST,INPP5B,ITPKB,KCNH2,NELL2,PDE4B,ABCB1,RETREG1,LRRN3,PTCH1,PTK2,FAM184A,RGS12,SATB1,SGK1,FAM102A,ST6GAL1,KDM4B,SATB2,SYNE1,VAV1" Coexpression M4444 Genes up-regulated in comparison of memory IgG IgA B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ADCY6,PDE8B,MARCH3,ZSCAN18,BAIAP3,DDR1,DGKI,LY86,CSF2RA,RIPOR2,TBC1D5,FRY,EBI3,RGS17,RASGRP2,CORO2B,DLL3,OGA,FYN,GABBR1,CHL1,GATM,GUCY1A1,SYNPO,IRF8,KPNA5,NTRK2,PCDH9,PDE4D,SNX10,MARCH1,TRIM68,RET,ZNF532,SYBU,SPTAN1,LHPP,SATB2,TTTY15,ATP6V0E2,KAT6A,NLRP3" Coexpression M6030 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus IL4 [GeneID=3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "METAP1D,TBC1D14,PITPNM2,CDK10,TMEFF1,ARRB1,ZBTB10,SYNJ2,CD86,AKAP7,SLC4A8,AHCTF1,ZFP28,UBXN2A,KIAA0753,CDON,E2F5,FLYWCH1,TPK1,KDM2B,FAM69A,KIF2A,TTYH2,MEST,PPM1L,ETFRF1,PLEC,ANKRD16,PRKAB2,RAP1GDS1,REV3L,DGLUCY,SCAF8,NUBPL,SLC9A5,EPC1,SS18,IQCE,TCF4,CYB561A3,ZNF346,MICU3" Coexpression M5302 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "BBOX1,MADD,CBFA2T2,CHN2,CPS1,CRY2,DCAF4,GPRASP1,RIPOR2,TBC1D5,USP3,RASGRP1,EEF1D,FAM13A,PLEKHA1,USPL1,RASGRP2,FCGRT,FYB1,GNAO1,ADAM22,MXI1,PCBP3,PCDHGC3,PRPH,PTCH1,C1orf54,ZNF331,SGK1,TTC17,PDZD2,ZBTB43,MCF2L,ATMIN,KAT6B,WNT7A,GDPD5,TUBA1A,MPPE1,MARCH8,ZNF37BP,NLRP3" Coexpression M9119 Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 and FOXP3 [GeneID=22807;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ABHD6,FGD2,TNRC6C,ARRB1,TMEM108,AP1M1,SPAG9,CD86,ZFP28,CNRIP1,AKAP12,GIT2,IRAK4,CALCRL,TLR7,EZH1,CHST15,SEC24B,ANKFY1,GLUL,FAM69A,MBP,ZNF655,PRKCB,C1orf54,ZNF493,SLC25A36,LRRK2,ZNF821,DHX30,SLC14A1,MTERF2,EPC1,INTS9,SP4,ARHGAP26,MPRIP,STX1A,KIAA1107,SZT2,TK2,TRIO" Coexpression M9361 Genes down-regulated in day 7 germinal center B cells versus day 7 plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "TXNDC16,BIN1,MYOM1,SPAG9,CD86,QKI,AKAP7,CTH,MYADM,RHOBTB1,OPTN,COQ7,PCYOX1,POMT1,TVP23A,TOX2,CFAP126,KTN1,PIK3AP1,BLOC1S2,CYTL1,PCDH18,DRAM2,PRKAB2,CNNM2,RAD17,ROGDI,BEND5,GTDC1,PTGR2,SH3BP2,MYO18A,ZNF667,ZFP90,VWCE,ANKRD24,DCBLD1,TSC1,ZNF213,PHTF2,JMJD1C,DPF3" Coexpression M6629 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus LPS and IL10 [GeneID=3486]. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "ADRB2,TBC1D14,GPR146,CAST,SOCS6,CNOT8,DOCK4,DCTN1,NR1D2,SLC12A6,ANKRD46,ING4,ETV1,TOX2,PTOV1,CNOT4,OPA1,TREM2,PKD1,ZFYVE21,RETREG1,PMP22,PRKAB2,BCAS3,RNASEL,SEMA6D,SEC14L1,CHD9,ST6GAL1,SIRT2,BTBD7,SEPT8,DIP2A,STX1A,SULF2,ANKRD28,CAMTA1,P2RY12,SPIRE1,RNF103,PLSCR4,FXR1" Coexpression M5367 Genes up-regulated in comparison of untreated macrophages versus macrophages treated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 3.83E-05 4.35E-01 1.19E-03 1.18E-02 42 200 "PPFIA4,CDC14B,ARNTL,DYNLL1,SCAPER,LDLRAD4,SLC25A14,SEC14L5,TM9SF4,GIT2,DDX46,PHC2,KMT5B,PRMT5,GABRA3,BRD8,ADGRA3,KAT7,INPP5B,NINJ2,PDE4A,PEX2,UBR7,CCDC82,DCUN1D2,PCMTD2,KCNIP1,ZNF821,ARHGEF40,RBM26,PBLD,ZC4H2,ARHGEF9,WSCD1,R3HDM1,TRPS1,ZKSCAN5,ZNF74,RNF103,PDSS2,EPM2A,LAS1L" Coexpression 19549311-SuppTable2-MMLandPhenotype Human Leukemia_Zangrando09_1001genes GeneSigDB 3.83E-05 4.35E-01 1.19E-03 1.18E-02 103 628 "ACTN1,FMNL2,ESYT2,AK2,ALCAM,GAS7,MARCH3,ZSCAN18,BCL7A,BID,WASF1,CAST,CD38,RCBTB2,MS4A7,RPL32P3,TPP1,LY86,HOMER3,CSF1R,ARHGEF10,CSNK1E,VCAN,CST3,PPP1R16B,GPSM1,RIPOR2,LONRF1,YTHDC1,NR1D2,RCAN1,EBF1,HIPK3,FRY,PLXNC1,AASS,PAN3,DCTN4,RPS6KC1,TBC1D16,PRAM1,SCML2,FCGR1A,FHL1,TPK1,FYB1,ZNF274,SEPT9,ADAM28,GPD2,NCKAP1L,IDH3A,IFI16,IL6R,FAM69A,ITGAM,JAK2,KIT,LAMP2,LIG4,SMAD1,PIK3AP1,LYPLAL1,MAT2A,MBNL1,MEF2C,MEIS1,NINJ2,NPY,P2RX7,ZNF827,CYTL1,SNX10,PLTP,PPP3CC,PTCH1,REV3L,RFX2,PRCD,GALNT10,COPZ1,SLA,ARHGEF40,SLC22A4,SMARCA4,ZNF423,SAMSN1,ZC4H2,NXT2,SYT1,DMXL2,KIAA0930,ZEB1,SIK3,TMPO,TPM2,SSBP2,TTC3,SGK3,KCNK12,ZXDA,SIGLEC10,MSRB3" Coexpression M244 Genes down-regulated in brain relapse of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.94E-05 4.47E-01 1.22E-03 1.21E-02 23 85 "KIAA1324,ALCAM,CA12,CLGN,CLCN3,COL4A5,SLC4A8,GREB1,ERBB4,EVL,TOX3,IL6ST,MAPT,QDPR,RET,STK32B,CXXC4,MAPKBP1,KDM4B,ASTN2,CHST8,NPDC1,DNALI1" Coexpression M9090 Genes up-regulated in CD4 T conv: control versus over-expression of LEF1 [GeneID=51176]. MSigDB C7: Immunologic Signatures (v6.0) 4.26E-05 4.84E-01 1.32E-03 1.30E-02 37 169 "FMNL2,PI16,APOC2,N4BP2L1,DOCK11,BARD1,CACNB4,EVI5L,MAGED1,CST3,CD99L2,CPEB2,MALT1,KCNJ16,KHK,MATK,RTL5,NCF2,PLCB2,PLCL1,SLC25A23,PPP3CC,ROGDI,RNASEL,TCP11L1,EMID1,SEC14L1,MYO18A,ATF7IP,SYNE2,PDLIM2,IQCE,ARHGAP9,TMPO,NPL,RPRM,DOCK8" Coexpression M13859 Genes up-regulated in hairy cell leukemia (HCL) compared with normal and other neoplastic B cell populations. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.39E-05 4.99E-01 1.35E-03 1.34E-02 22 80 "GAS7,ARRB2,DST,RCBTB2,SUSD5,PDE4DIP,SLITRK5,DAPK1,PLXNC1,EPB41L2,DLC1,FGFR1,HPGDS,GABARAPL2,NOVA1,PCDH9,MAPK10,SYT1,TACC1,CAMTA1,TRIM2,TIMP4" Coexpression M344 Genes up-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and the HIV matrix protein p17. MSigDB C7: Immunologic Signatures (v6.0) 4.42E-05 5.02E-01 1.36E-03 1.35E-02 36 163 "RNF157,WDR35,BLM,SYNJ1,ARHGEF7,MTMR2,AP1M1,TAOK2,ARMCX2,DNAJC27,USP21,TNRC6A,DIDO1,KAT7,KCNF1,LYPLAL1,RETREG2,VPS13C,RASGRF2,CASC3,SUPT20H,FNDC3A,R3HDM2,CCDC88A,NAPB,TTC17,USP33,POGZ,TTBK2,DNMBP,SIK3,ZNF106,R3HDM1,DOCK8,RTN4,CPNE4" Coexpression M2603 "Top 40 genes from cluster 13 of acute myeloid leukemia (AML) expression profile; 91% of the samples are FAB M2 subtype, all bear the t(8;21) translocation producing the AML1-ETO fusion [GeneID=861;862]; indicate good survival." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.53E-05 5.15E-01 1.39E-03 1.38E-02 12 30 "MYRF,BAIAP3,THSD7A,RUNX1T1,CACNA2D2,NCALD,NBL1,ROBO1,STK32B,KDM4B,VLDLR,LAT2" Coexpression M3100 Genes up-regulated in comparison of macrophages treated with control (hIgG1) versus those treated with TNFRSF6B [GeneID=8771]. MSigDB C7: Immunologic Signatures (v6.0) 4.57E-05 5.19E-01 1.40E-03 1.38E-02 41 195 "AP2A2,KSR1,ASIC3,TPP1,HOMER3,CSF2RA,DAPK1,ZC3H11A,RHOBTB1,HS3ST2,ABCC5,WDPCP,SEMA4D,FOLR2,CAMKK2,CBX1,KCNMB4,KAT7,USP51,SMAP1,IRF8,INPP5B,LSS,COMMD5,LYRM9,P2RX7,PLEC,RIPOR1,PID1,LRRK2,ARHGAP26,IQSEC2,ERBIN,ARHGAP9,NR2C2,TTTY15,NPDC1,ZFAND5,MPPE1,MARCH8,RNF146" Coexpression 17312329-SuppTable2 Human Leukemia_Juric07_617genes GeneSigDB 4.76E-05 5.41E-01 1.45E-03 1.44E-02 78 449 "ADCY6,ADD2,SEMA6A,SPOP,AMH,RIPK1,BMPR1B,CASTOR3,JAZF1,CAST,FOXN3,CHN2,NRXN3,CNN3,OSBPL3,VCAN,RIPOR2,ARHGAP24,RASGRP1,EPB41,NRN1,FECH,TMEM164,PDLIM5,PRELID3A,TPPP3,FYN,ADAMTS6,IRAK3,RASSF8,HBA1,TOX2,ICA1,RBPJ,TTYH2,NEXMIF,MYT1,NF1,NFIX,NTRK3,NUCB2,PDE1B,DUSP26,PKM,SCHIP1,IRX1,GRAMD1C,PTPRB,PRIMA1,SETD5,KLHDC8A,FBXW7,BAALC,RTN1,ZNF331,SLC2A5,BTBD3,SLC6A8,SLC14A1,LIMCH1,SNCA,ITPRID2,CEP68,PRRC2C,ANKRD28,ZEB1,SIK3,SLC44A1,CSMD1,TNS1,TRIO,TRPS1,DCBLD1,OSBP2,NPDC1,ZNF184,SLC38A1,RGS7BP" Coexpression 14695196-Table2 Human Colon_Mariadason03_420genes GeneSigDB 4.85E-05 5.51E-01 1.47E-03 1.46E-02 57 302 "AMPD3,CDC42BPA,EP400,APC,CHID1,FUBP1,TPP1,CNN3,CLOCK,TRIM69,GREB1,SEC14L5,DAPK1,SACS,TSPAN5,HIPK3,HEYL,EGR3,KCTD3,EIF5,TBC1D16,SCARA3,FOXO3,FOLH1,SPIN1,RAB40B,PSIP1,ADAMTS6,SHISAL1,LIFR,NF1,NFYA,NNAT,SLC11A2,NUCB2,ABCB1,APTX,RDX,PBRM1,ZNF532,TMLHE,SEC31A,ZHX3,GLT8D1,ADHFE1,TBCEL,AP4E1,ACTR6,PDSS1,DCBLD1,TTC3,UBE3A,CLIP2,ZNF19,POLR3H,SMARCAD1,EVI5" Coexpression M25 Genes up-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.98E-05 5.66E-01 1.51E-03 1.50E-02 16 49 "PPFIA4,APC,DLGAP1,GREB1,DGCR5,MTHFD2,PTPRT,MN1,ADAM22,PTH1R,REV3L,ANKRD6,DOP1A,ZNF423,TPM2,TSC1" Coexpression 19843711-TableS2 Human Kidney_Sallustio10_2134genes_CompleteListAnalysis GeneSigDB 5.00E-05 5.68E-01 1.51E-03 1.50E-02 237 1674 "ABR,ACTN1,AK2,C1QTNF3,SPOP,SRPX,BIN1,OGT,APBA2,APLP1,SHROOM2,CDC14B,ARHGDIA,RGS20,CDK13,ZSCAN18,RASL11B,ATP1A1,SLC4A4,ATP1B3,ATP2A2,BARD1,BID,CFLAR,PROM1,ST3GAL5,RAB29,DDR1,CALM1,CAMK2G,CAST,CARS,HIP1R,USP2,LRBA,CDC25B,LRRFIP1,CRLF1,UBE2L6,CHRNA4,SLIT2,CLCN3,CLTB,FBXO7,MAP4K4,FAM149A,COL4A5,COX4I1,AKAP12,HAPLN1,SIPA1L1,VCAN,SOCS5,PDE4DIP,PHF14,HDAC9,GAPVD1,DAPK1,DAPK3,BRINP1,ARMCX2,GSDME,DNM1,RCAN1,ECM2,RASGRP1,FAM13A,EGFR,EIF4G2,ELN,EIF1,EMX2,GPHN,RABEPK,EXTL2,ABCA8,CORO2B,RACK1,PRMT5,FGFR3,AMOTL2,FHL1,SEC23B,IP6K2,PDLIM5,STAMBP,TPK1,GABBR1,DENND2A,ERAP1,MTHFD2,MALT1,GLUL,FERMT2,PRRC2B,GPER1,GSN,PSIP1,GUCY1A1,GUCY1B1,HAS2,PACSIN2,HMGCL,AGFG1,ICA1,IFI16,SHISAL1,IL6ST,FAM69A,ITGA7,KCNJ16,KCNK3,KHK,IPO5,L1CAM,LAMA2,SMAD9,MAP4,MAPT,MATN2,MBNL1,MBP,MEIS2,MEST,MID1,MITF,AFF1,TAGLN3,MYO6,MYO9A,NFIX,NOVA2,NRCAM,NTRK2,NUCB2,PCSK5,PDCD2,PDE1C,PDE4B,ENPP2,PFKFB3,OLA1,ABCB1,PKD1,RETREG1,PKM,PLEC,PLTP,PMP22,TRHDE,PSAT1,PPM1B,PPP1R1A,PKIA,NDUFS7,PTK2,PTPRD,PTPRG,PTX3,RAD17,SUSD4,RBBP6,RBBP8,MORC4,UBR7,RGS4,RNH1,PCMTD2,NEK11,RPS6KA2,STK32B,KCNIP1,CLIP1,RYR3,SARS,GALNT10,ASAP3,SHMT2,FHOD3,ST6GAL1,SEC31A,DZIP1,LIMS2,SLC6A8,SLC8A1,ARHGEF40,OGDHL,USP33,FNBP1,GLT8D1,MYCBP2,SPP1,UNC5B,ZNF423,SPTAN1,CDK19,NFASC,CLSTN2,THSD1,MPRIP,PRRC2C,SYNE2,DNAJC9,PLCB1,TBL1X,TCEA1,WSCD1,SATB2,PCDHGC5,SYNE1,ZFPM2,GPR161,TIAM1,BEX4,PARD3,TP53BP2,TPM1,TPM2,METTL3,TSC1,SSBP2,TTC3,UBE2H,UCHL1,UGT8,USP1,WNT7A,ZNF24,ATP6V0E2,NDRG4,ZNF195,FTSJ1,TUBA1A,NAV3,TRIM16L,PHTF2,FXR1" Coexpression M4680 "Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.04E-05 5.72E-01 1.52E-03 1.51E-02 50 255 "ADD1,ALK,ANK2,TMEFF1,ARRB1,MARCH3,BCHE,NRP2,ST3GAL5,MAP4K4,CREM,AKAP12,CSNK1E,JAKMIP2,GSDME,RHOBTB1,E2F5,PLXNC1,LRRC17,EYA1,RASL10A,DENND2A,GAD1,GATM,PCDH17,MSL3,HMGCR,INPP1,FAM69A,ITPKB,KCNN3,SMAD1,MMP16,MN1,MYCN,NRCAM,PCSK5,MAGEL2,EPB41L4B,WBP1L,SPDL1,PTPRE,MORC4,STK32B,MEG3,SATB1,GALNT10,SGK1,NFASC,DICER1" Coexpression M6241 Top 40 genes from cluster 8 of aculte myeloid leukemia (AML) expression profile; 69% of the samples are FAB M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.09E-05 5.78E-01 1.52E-03 1.51E-02 11 26 "CDC42BPA,ABCG2,TSPAN5,OPTN,FECH,MXI1,SLC6A8,SNCA,TAL1,TNS1,OSBP2" Coexpression M16673 "Top 40 genes from cluster 16 of acute myeloid leukemia (AML) expression profile; 81% of the samples are FAB M5 subtype, 45% have 11q23 abnormalities." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.09E-05 5.78E-01 1.52E-03 1.51E-02 11 26 "C3orf14,AK2,APOC2,ITGA7,KCNN2,MBNL1,C1orf54,RET,CLSTN2,KCNE5,LAMP5" Coexpression 14997935-Table1 Human Brain_Mukasa04_29genes GeneSigDB 5.09E-05 5.78E-01 1.52E-03 1.51E-02 11 26 "HCN2,CHGB,RIMS2,SNAP91,OLFM1,L1CAM,MBOAT7,PSD,FAM102A,SH3GL3,KCNAB1" Coexpression M3321 Genes up-regulated in comparison of resting CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.16E-05 5.87E-01 1.54E-03 1.52E-02 41 196 "NDRG2,GPRASP2,APBA2,TIGD7,PREPL,ARHGAP32,DCAF8,TENM1,APOPT1,CELF1,SARAF,ACSS1,RUNDC3A,PRRC2B,PSIP1,ADAMTS6,LINC01550,CPT1C,IL6ST,CCDC13,NELL2,TMOD2,PRKACB,PTK2,TUG1,ZNF493,RADX,FAM161B,ATXN7,ATF7IP,COA1,ANKFN1,SNRPN,RBM26,ERBIN,NR2C2,TRO,LMF1,ZNF711,AMN1,KAT6A" Coexpression M5765 Genes down-regulated in comparison of untreated macrophages versus those treated with IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 5.16E-05 5.87E-01 1.54E-03 1.52E-02 41 196 "ALK,AZGP1,CA8,RHBDL1,LDB2,ENTPD2,AKAP6,CABP1,COL9A3,SNCAIP,FAM169A,DCAF8,ARMCX4,EDN3,AASS,CPLX2,GGT5,STMN2,ATXN2L,HNF4G,C2orf72,KIT,MEIS2,SAMD14,MYO9A,PTK2,MORC4,FBXW7,STK32B,SBF1,SCN2B,SMPD3,SLC6A11,IQSEC2,MMS19,CDK20,METTL3,CA14,PLPPR2,MKRN3,FAM182B" Coexpression M8187 Genes down-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 5.31E-05 6.03E-01 1.58E-03 1.56E-02 38 177 "ADD1,ALCAM,ATP6V0A1,DOCK11,SYNJ1,CACNA1I,CDC25B,ANKRD44,CSNK1G3,MYADM,RIPOR2,FAM107B,FRY,PAN3,RASGRP2,CHST15,GPD2,ADAMTS6,BACH2,IRF8,FAM69A,JAK2,LMO2,MEF2C,PDE4B,RETREG1,PPP3CA,SATB1,RASA3,ATF7IP,LMBRD1,ARHGAP26,CDK19,STAC2,DNAJC9,SSBP2,RICTOR,TUBA1A" Coexpression M11363 A cluster of genes specifically up-regulated in gastrointestinal stromal tumors (GIST). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.44E-05 6.18E-01 1.61E-03 1.59E-02 25 98 "PWWP2A,AMPD3,DPP10,ARRB1,SLC4A4,PROM1,SYNJ1,CHN2,ANKRD44,DYNC1I1,ETV1,MRVI1,GUCY1A1,KLHL23,KIT,LMO2,MYO6,ABCB1,HSPA4L,BTBD3,SLC12A2,ZMAT3,DOK6,SLC38A1,RGS7BP" Coexpression 11823860-SuppTable3 Human Breast_van'tVeer02_2460genes_Ergenes GeneSigDB 5.46E-05 6.20E-01 1.61E-03 1.60E-02 266 1910 "NDRG2,FMNL2,FZD9,RNF150,PTCHD1,MTA3,TBC1D14,KIAA1324,TXNDC16,SPARCL1,SPOP,USP35,ALCAM,BBOX1,SYT13,BIN1,EPB41L5,PHYHD1,BCAS1,PDE8B,CHRD,ATP1B3,RNF182,AZGP1,ADGRB2,MPDZ,BLM,PROM1,BMPR1B,MTMR2,RAB29,BAIAP3,CA12,DDR1,CALB2,PTBP2,PRC1,CBR1,CLDN10,CD86,LRBA,CDC25B,LONRF2,MAGI1,CLGN,CRLF1,NUMBL,PLEKHB1,CLCN3,NGEF,CNN3,COL4A5,LETMD1,COL9A3,TBPL1,COX4I1,MYRIP,IGDCC3,PREPL,SH2B1,ABCG1,LRIG1,CSNK1G3,IPCEF1,FAM169A,KIAA0040,GREB1,CYBB,ARHGAP32,RASSF2,DAPK1,SPOCK2,AIF1L,GIT2,DBN1,ARMCX2,MYEF2,SACS,SGSM2,TMCC2,SEC16A,DMD,CPEB2,DOCK2,RCAN1,DUSP9,ABCC5,DNM1L,GOLT1B,EDN1,OPTN,KMT5B,KCTD3,PCOLCE2,PAN3,VPS13B,COQ7,LRRC17,RASGRP2,GPHN,ERBB4,IGSF6,SPEG,MRPL37,ACSL4,TUBB3,FCGR1A,CHST15,TMEM164,SCARA3,UBE2E3,IP6K2,AGAP2,SYNCRIP,EVL,SEMA4D,COQ5,JKAMP,NBEA,FAM49B,TRIM16,ATP2C1,KHDRBS3,SARAF,FYB1,MTHFD2,GPR162,PPARGC1A,DHRS4,BRD8,TOX3,GLUL,KDM2B,GNG4,GPT2,PRRC2B,LILRB4,SERP2,PTPRT,FAM107A,SLC2A6,PADI2,FRMD3,NCKAP1L,BACH2,VSIG4,ELOVL5,ACOT7,HMGCL,AGFG1,TCEAL6,ICA1,IFI16,IL6ST,LAMP2,STMN1,SFXN5,SYTL4,NCOA7,PIK3AP1,AQP11,MATN3,KCTD6,MID1,AFF1,MYO6,NCF2,NELL2,NOVA1,PALM,PCDH8,PDE4B,RETREG1,XRN1,GPSM2,PLTP,MTRF1L,LRP12,PSAT1,SH3KBP1,POLR2F,MAPK9,SLC26A11,KLK6,DEF8,PIGG,ELOVL2,PTPN13,PTX3,TTC13,QDPR,ROGDI,RDX,FIGN,RNASE1,CCDC82,ZNF532,ELP2,PCMTD2,ZNF671,RTN1,AP1AR,FNIP1,MRAS,FAM102A,KIF16B,SHC4,SYBU,ST8SIA1,ABLIM3,SLA,SLC2A5,SLC9A5,SLC11A1,CPEB4,CXXC4,KDM4B,BDP1,FNBP1,SOX11,ZHX3,UNC5B,DBNDD2,CDK19,SAMSN1,ERBIN,NEK4,RGL1,SULF2,SEPT3,STXBP1,ASTN2,AGTPBP1,TRIM2,USP22,PCDHB10,TNS2,GPR161,SLC44A1,TMPO,TP53BP2,PDSS1,STXBP4,TRPS1,SSBP2,SGK3,RPRM,UBE3A,UCHL1,UGT8,USP1,NPDC1,ZIC1,ZNF711,LYPD6,MEIS3,PRTFDC1,DNALI1,RNF103,ITM2C,HRASLS,TMEM63C,ACTR3B,TTC7A,NHSL1,FRMD6" Coexpression M904 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.60E-05 6.37E-01 1.65E-03 1.63E-02 47 236 "SEMA6A,OGT,PKP4,TNRC6C,BCL7A,FUBP1,C5,CBFA2T2,AHCTF1,RBM39,NCOR1,SNCAIP,EARS2,MED12,E2F5,E2F6,EEF1D,EPB41,SCARA3,USP21,ATP2C1,ACSS1,GCNT2,MAP7D2,ZNF496,CLASRP,AGBL5,LIFR,MAN2A2,MAT2A,MGAT3,MYCN,NFYA,CLDN11,PPM1B,PTCH1,ROBO1,EMID1,TRA2B,SEPHS1,IFT122,POGZ,GPR161,TMPO,SYNPO2,XPO1,ATP6V0E2" Coexpression M8144 "Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.61E-05 6.37E-01 1.65E-03 1.63E-02 145 952 "RALGAPA1,FMNL2,BRAP,PLEKHH1,ESYT2,HACE1,OGT,CDC42BPA,PKP4,GAS7,USP37,ARRB1,NUMB,STX16,BID,KSR1,SYNJ1,ARHGEF7,SCAPER,CAST,CARS,CBS,SCARB1,CCPG1,UBE2L6,NPIPA1,RCBTB2,FOXN3,ARMC8,LETMD1,ENTPD4,RBM39,PNPLA8,CTH,CYBB,HDAC9,EARS2,DBN1,DDX46,USP3,NR1D2,CPEB2,SLC12A6,ARRDC4,ABCC5,KLHL5,FSD1L,MBNL2,LINC-PINT,EIF5,IRAK4,PLEKHA1,ING4,EIF1,RABEPK,ANKMY1,CD320,RPS6KC1,SH3YL1,PTK2B,FCGR1B,GORAB,NOP56,TPK1,OGA,FYN,ZNF274,ERAP1,MTHFD2,INPP5K,USP19,TXNL4A,GPT2,ADGRA3,GRB10,SPACA9,PSIP1,MGC16275,MIER3,HMGCL,AGFG1,INPP1,ITPKB,LSS,MIA2,MYO5A,ZNF862,NEK1,ALDH1L2,OGG1,PDE4D,PKD1,RETREG1,SMOX,PRIMPOL,PSAT1,POLG,TATDN3,PRKACB,APTX,PTPRE,TUG1,PPP2R3C,CEP97,RAD51D,RET,RFX3,SLC25A36,ADAL,TCP11L1,CLIP1,SARS,SEC14L1,SH3BP2,SHMT2,CCDC92,CPEB4,GKAP1,UHRF1BP1L,CDK19,ZNF621,ZSCAN29,TTBK2,PRRC2C,ARHGEF9,MLST8,TAF9,TBL1X,TCF4,TCF12,ARHGAP9,AKTIP,CBX5,SSBP2,UBE2H,FLRT2,VLDLR,PCBP1-AS1,FTSJ1,EMSY,TUBA1A,VPS35L,ACTR3B,NHSL1,RNF146" Coexpression 18614019-TableS4a Mouse StemCell_Fazzio08_722genes GeneSigDB 5.63E-05 6.40E-01 1.65E-03 1.64E-02 86 509 "MTUS1,OSBPL1A,WDR35,AMPD3,OGT,PPFIA4,APOC1,CDC14B,IGDCC4,ADGRB1,CFLAR,SYNJ2,SCAPER,KALRN,PTBP2,ARHGEF25,CBFA2T2,MAP4K4,ARMC8,SMARCAL1,CLIP3,GALNT9,VCAN,ERC2,GPRASP1,SPOCK2,DDX46,SACS,TMCC2,DMD,DTNA,HIPK3,ING4,DCTN4,ENO2,VPS13B,ZMYND10,FGF1,IP6K2,SYNCRIP,CGREF1,FUT9,GABBR1,TRAF3IP2,DCLK2,GRB10,PSIP1,HAS2,PADI2,FRMD5,CELF5,KNDC1,MATK,MID1,NME4,KCTD15,PLXNB1,EPDR1,PTCH1,PPP2R3C,RGS3,SLC25A36,FNIP1,CHD9,ST8SIA1,SEPHS1,TRIM67,IFT122,KIF13A,IZUMO4,ADHFE1,PJA1,MCF2L,DNMBP,OBSL1,AKTIP,ARL10,TMPO,TPM1,TRO,VLDLR,MICU3,MAP3K12,SLC38A1,PCBP4,RNF170" Coexpression 19061838-TableS3 Human Viral_Cairo08_588genes GeneSigDB 5.81E-05 6.61E-01 1.69E-03 1.68E-02 80 466 "ACADM,NDRG2,OSBPL1A,ALCAM,BBOX1,LGR5,N4BP2L1,MYOM1,AZGP1,CBS,MAP4K4,FAM149A,MAGED1,CREM,CRHBP,CS,SOCS5,DZIP3,CTH,GREB1,MFAP3L,RHOBTB1,PLXNC1,AASS,TENM1,ETV1,RPS6KC1,ST3GAL6,FDFT1,PDLIM5,GABBR1,SYT17,GHR,PPARGC1A,LYVE1,GLUL,CBX1,ADGRA3,GPD1,GSTT2,VSIG4,HMGCR,HP,IGF1,INPP1,MT1M,PDCD2,RETREG1,FXYD1,PPP1R1A,GRAMD1C,PRODH,RELN,PTH1R,ACSS3,SLC25A36,ROBO1,MEG3,SCP2,FAM102A,CPEB3,ABLIM3,SEPHS1,SMARCA4,OGDHL,RCOR3,PEG10,SEPT8,CEP68,TACC1,OBSL1,CBX5,R3HDM1,TSN,ZBTB38,ZNF189,ZFAND5,MFF,MARCH8,FXR1" Coexpression M2128 Genes up-regulated in growing IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.82E-05 6.61E-01 1.69E-03 1.68E-02 48 243 "CDC42BPA,VAT1L,CA12,RUNX1T1,LDB2,CDC25B,SLIT2,NRXN3,TSPAN5,LRRC17,FAM198B,FGF1,SCARA3,SMC2,PSIP1,ADAMTS6,HAS2,IFI16,KCNN2,LSAMP,MATN2,MEIS2,MEST,ALDH1L2,CLDN11,OXTR,CNTN3,PSAT1,ZFHX4-AS1,ELOVL2,PTN,PTX3,RBBP8,UBR7,RGS4,BAALC,PEAR1,SHMT2,FBXO11,SLC14A1,DNAJC9,ANKRD28,ITGB3BP,CBX5,TMPO,TTC3,USP1,DPF3" Coexpression M3133 Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 5.83E-05 6.62E-01 1.69E-03 1.68E-02 41 197 "KDM5D,TMCC3,MTA3,AP2A2,WDR35,BCHE,USP6,RAB33A,CREM,LYPD1,GSDME,MED12,SLC12A6,ARMCX1,SH3YL1,POMT1,ERGIC3,ZNF274,GPR34,ATP2B1-AS1,MGC16275,CELF5,LMO2,MATK,MBP,PTOV1,SFR1,NFE2L2,NME4,TREM2,PDE4A,RPS6KA2,IFT122,LMBRD1,SPATA7,ADHFE1,VPS13A,ARHGAP9,TNS1,ZNF24,SPIRE1" Coexpression M7728 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 6.02E-05 6.84E-01 1.74E-03 1.73E-02 35 159 "RNF157,ARNTL,BACH1,CBFA2T2,EVI5L,PPT2,CSNK1E,PPP1R16B,HDAC9,DGKG,MBNL2,PAN3,SEC24B,SEMA4D,BACH2,HSF2,KCNH2,LIG4,XRRA1,NTRK3,PFKFB3,STRN3,PRODH,TTC13,FAM161B,ANKRD6,BTBD7,MAPKBP1,SLC37A2,TACC1,TCF12,PRRT1,SLC38A1,PARP11,NHSL1" Coexpression 19303107-Table3 Mouse Bladder_Price09_85genes GeneSigDB 6.02E-05 6.84E-01 1.74E-03 1.73E-02 21 76 "ALCAM,WASF1,CDH2,SLIT2,HAPLN1,VCAN,BRINP1,HEPH,EDIL3,EPHB1,MEGF10,CHL1,KIT,MYO6,PTN,ZFHX4,SOX11,SEPT3,ZFPM2,TRO,PCBP4" Coexpression M2745 Genes down-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes. MSigDB C6: Oncogenic Signatures (v6.0) 6.16E-05 7.00E-01 1.78E-03 1.76E-02 40 191 "NDRG2,APLP1,ASGR1,NRP2,BLM,BTK,LY86,PCYT1B,CABP1,CRYM,FAM131B,GIT2,SV2B,MBNL2,RCAN2,EPHB1,ZNF549,FER,SYT17,GPR12,STON1,GRIN2C,SMAP1,IRF8,PACRG,SMAD9,NELL2,NOVA1,PCDH9,PLCD1,SMARCD3,PLCB1,TNS2,NR2E1,TRO,WIPF1,ZIC2,SEMA3B,FAM182B,JPH3" Coexpression M988 Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.23E-05 7.08E-01 1.79E-03 1.78E-02 34 153 "ARRB1,LDB2,KRIT1,SLC16A4,TPP1,COL4A5,MAGED1,SNCAIP,LRIG1,EDNRA,EXTL2,EYA1,ACSL4,CHST15,FCGRT,FOXF2,IQGAP2,STON1,GSN,HNMT,MEIS1,ENPP2,PTPN13,ZNF532,ROBO1,PCMTD2,SNAP25,SPP1,TCF12,HEY1,TIMP4,TRO,SSBP2,FLRT2" Coexpression 19843711-TableS1 Human Kidney_Sallustio10_2134genes_DiscriminatedARPCsFromRPTEC/MSC GeneSigDB 6.29E-05 7.15E-01 1.81E-03 1.79E-02 238 1688 "ABR,ACTN1,AK2,C1QTNF3,SPOP,SRPX,BIN1,OGT,APBA2,APLP1,SHROOM2,CDC14B,ARHGDIA,RGS20,CDK13,ZSCAN18,RASL11B,ATP1A1,SLC4A4,ATP1B3,ATP2A2,BARD1,BID,CFLAR,PROM1,ST3GAL5,RAB29,DDR1,CALM1,CAMK2G,CAST,CARS,HIP1R,USP2,LRBA,CDC25B,LRRFIP1,CRLF1,UBE2L6,CHRNA4,SLIT2,CLCN3,CLTB,FBXO7,MAP4K4,FAM149A,COL4A5,COX4I1,AKAP12,HAPLN1,SIPA1L1,VCAN,SOCS5,PDE4DIP,PHF14,HDAC9,GAPVD1,DAPK1,DAPK3,BRINP1,ARMCX2,GSDME,DNM1,RCAN1,ECM2,RASGRP1,FAM13A,EGFR,EIF4G2,ELN,EIF1,EMX2,GPHN,RABEPK,EXTL2,ABCA8,CORO2B,RACK1,PRMT5,FGFR3,AMOTL2,FHL1,SEC23B,IP6K2,PDLIM5,STAMBP,TPK1,GABBR1,DENND2A,ERAP1,MTHFD2,MALT1,GLUL,FERMT2,PRRC2B,GPER1,GSN,PSIP1,GUCY1A1,GUCY1B1,HAS2,PACSIN2,HMGCL,AGFG1,ICA1,IFI16,SHISAL1,IL6ST,FAM69A,ITGA7,KCNJ16,KCNK3,KHK,IPO5,L1CAM,LAMA2,SMAD9,MAP4,MAPT,MATN2,MBNL1,MBP,MEIS2,MEST,MID1,MITF,AFF1,TAGLN3,MYO6,MYO9A,NFIX,NOVA2,NRCAM,NTRK2,NUCB2,PCSK5,PDCD2,PDE1C,PDE4B,ENPP2,PFKFB3,OLA1,ABCB1,PKD1,RETREG1,PKM,PLEC,PLTP,PMP22,TRHDE,PSAT1,PPM1B,PPP1R1A,PKIA,NDUFS7,PTK2,PTPRD,PTPRG,PTX3,RAD17,SUSD4,RBBP6,RBBP8,MORC4,UBR7,RGS4,RNH1,PCMTD2,NEK11,RPS6KA2,STK32B,KCNIP1,CLIP1,RYR3,SARS,GALNT10,ASAP3,SHMT2,FHOD3,ST6GAL1,SEC31A,DZIP1,LIMS2,SLC6A8,SLC8A1,ARHGEF40,OGDHL,USP33,FNBP1,GLT8D1,MYCBP2,SPP1,UNC5B,ZNF423,SPTAN1,CDK19,NFASC,CLSTN2,THSD1,MPRIP,PRRC2C,SYNE2,DNAJC9,PLCB1,TBL1X,TCEA1,WSCD1,SATB2,USP22,PCDHGC5,SYNE1,ZFPM2,GPR161,TIAM1,BEX4,PARD3,TP53BP2,TPM1,TPM2,METTL3,TSC1,SSBP2,TTC3,UBE2H,UCHL1,UGT8,USP1,WNT7A,ZNF24,ATP6V0E2,NDRG4,ZNF195,FTSJ1,TUBA1A,NAV3,TRIM16L,PHTF2,FXR1" Coexpression M8215 Genes in the expression cluster 'HSC and Progenitors Shared': up-regulated in hematopoietic stem cells (HSC) and progenitors from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.48E-05 7.36E-01 1.85E-03 1.84E-02 109 681 "KIAA1211,PITPNM2,PKP4,NT5C3B,ZBTB10,LDHD,CAMK2A,USP2,CBFA2T2,ARHGEF2,DCLK1,ZMYM4,RAB26,AKAP6,SLC4A8,ZNF521,CNRIP1,C2CD2,CREM,SH2B1,SEC24C,OSBPL3,ARHGAP32,EARS2,RASSF2,DAPK1,SPOCK2,ARMCX2,JAKMIP2,KIAA0753,RHOBTB1,PDCD6IP,DNM1L,EDIL3,SLC43A2,TBC1D16,TAOK3,PRKAG2,SEC23B,AGAP2,TMEM175,STAMBP,TPK1,KHDRBS3,NSG1,SARAF,TPPP3,MEGF10,SESN1,CBX1,GPR12,SPACA9,PRDM5,CLASRP,HSPA1L,GPR62,KIT,SYTL4,SMAD1,SMAD9,MAN2A2,MEF2C,MEIS1,MGAT3,MN1,PTOV1,MYCN,NCAM2,NDP,SFR1,SMIM11A,NTRK3,OCRL,ZNF827,PRTG,SEMA5B,EPB41L4B,PPP2R2C,MTMR10,NKAIN1,RET,RGS3,SLC25A36,TMLHE,PLPPR3,SCN8A,DHX30,TET1,SPART,LHPP,THSD1,MPRIP,STXBP1,PRRC2C,FBXW11,CRTC1,TEK,DICER1,NPL,DCBLD1,FAM155A,MTCH1,PLPPR2,LGI4,LYPD6,FSTL5,DHX33,STOX2,ACTR3B" Coexpression M5580 Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 6.57E-05 7.46E-01 1.87E-03 1.85E-02 41 198 "BIN1,APLP1,SCAPER,DCLK1,CCPG1,RCBTB2,STOML1,NRG2,ENTPD4,DOCK4,ZNF337,SGSM2,NR1D2,E2F5,RASGRP1,EEF1D,EZH1,F8,MALT1,MSL3,PRRC2B,BTN2A1,HNF4G,HSPA1L,L1CAM,MBD1,MGAT3,MYO6,ACSS3,ZNF532,SCN2B,R3HDM2,INAVA,CEP68,PHF24,UBE3A,ZIC1,ZSCAN26,SLC30A3,GDPD5,NAV3" Coexpression M5495 Genes down-regulated in comparison of macrophages versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 6.57E-05 7.46E-01 1.87E-03 1.85E-02 41 198 "MARCH3,CARS,SYNGR3,LOC730101,NDST3,STOML1,OSBPL3,KIAA0040,TBC1D5,MAML1,GIT2,E2F5,EEF1D,EGR3,TNK2,PTK2B,RNPS1,RNFT2,MUM1,HSF2,KCNH2,MAT2A,MEIS1,CNOT4,POLG,PRPSAP2,ZCWPW1,ZDHHC4,ROBO1,SATB1,SMPD3,PPM1E,CDK5RAP3,ZNF667,ZC4H2,ARHGEF9,CLASP1,SYNE1,ITM2C,MARCH8,LAS1L" Coexpression 20937356-TableS1 Rat Hypothalamic_Mansuy10_1270genes GeneSigDB 6.71E-05 7.63E-01 1.91E-03 1.89E-02 137 894 "NDRG2,ADCY5,ZNF608,HECW2,C1QTNF1,SRPX,ARHGAP20,GPRASP2,GAS7,SHROOM2,ASGR1,MARCH3,RASL11B,N4BP2L1,BMP7,RUNX1T1,UBE2L6,TAOK2,AKAP7,MAGED1,CNRIP1,ENTPD4,GDA,CLIP3,CST3,GPSM1,FAM131B,DCAF8,RASSF2,DAPK1,HEPH,ELMO1,CHRDL1,CDON,RCAN1,FIS1,EBF1,EDNRA,EDNRB,CNNM1,IRAK4,ING4,ENO2,RCAN2,RASL12,CD320,EZH1,FAM198B,ACSL4,CHST15,FCGRT,FHL1,SCARA3,FOXO3,ERGIC3,SARAF,BRSK1,FAM120B,SESN1,GGT7,GLI2,GRIA2,GSTM5,ATOH8,IRAK3,HP,CPT1C,JAK2,KCNJ16,LIFR,LIG4,LMO2,LSS,SMAD9,LYPLAL1,MGAT3,MN1,MOV10,MSI1,NPR2,NPTX1,SLC11A2,PDE4B,FXYD1,SEPT4,POU6F1,PCDHB17P,MASP1,CNNM2,BCAS3,LAMA1,GDPD2,PTCH1,FAT4,OXR1,GAL3ST4,ROBO1,ROBO2,PCMTD2,PLPPR3,RXRA,SALL1,SEMA6D,SCP2,PEAR1,ST6GAL1,OGDHL,IFT122,PDZRN3,MYCBP2,UNC5B,LHPP,ST5,ADHFE1,SULF2,RHBDL3,CAMTA1,OBSL1,CYB561A3,ZFPM2,SLC44A1,THRA,TMEM9,TPM1,IL34,SYNPO2,SSBP2,FLRT2,PLEKHH2,CCDC136,NPDC1,ZIC1,ZIC2,SEMA3B,ITM2C,PARP11,FBXO36" Coexpression M18322 Genes up-regulated in RD-EF cells (rhabdomyosarcoma) engineered to express EWSR1-FLI1 fusion [GeneID=2130;2313] and which are also highly expressed in Ewing's famliy tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.10E-05 8.07E-01 2.01E-03 1.99E-02 23 88 "PPFIA3,ATP1A1,GYG2,KYAT1,CCK,ARHGEF1,CHN2,CSNK1E,DAPK1,DPYSL2,FCGRT,OLFM1,CSPG5,MAN2A2,MAPT,NELL2,PRKCB,ST6GAL1,WDR47,FNBP1,SYT1,TRIM2,SLC17A7" Coexpression 15930281-Table1 Human BoneMarrow_HuLieskovan05_107genes GeneSigDB 7.10E-05 8.07E-01 2.01E-03 1.99E-02 23 88 "PPFIA3,ATP1A1,GYG2,KYAT1,CCK,ARHGEF1,CHN2,CSNK1E,DAPK1,DPYSL2,FCGRT,OLFM1,CSPG5,MAN2A2,MAPT,NELL2,PRKCB,ST6GAL1,WDR47,FNBP1,SYT1,TRIM2,SLC17A7" Coexpression M5682 Genes down-regulated in comparsion of ActTreg versus ActTregTGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "MTA3,MTUS1,CDC14B,STX16,MTMR3,LDLRAD4,CD38,AKAP5,MYRIP,IPCEF1,GREB1,ARHGEF4,GIT2,EXOG,C8orf37,TBC1D16,PRKAG2,FUT9,LPAR4,GPER1,STMN2,GUCY1B1,MYO9A,IGSF11,P2RY1,GNG2,POU6F1,WBP1L,PTPRO,ROBO1,ST8SIA1,SLC11A1,MAPKBP1,DBNDD2,SPTAN1,TSPYL2,ZSCAN29,ANKRD12,USP22,TTC3,NDRG4" Coexpression M7550 Genes up-regulated in double positive thymocytes with ELK4 [GeneID=2005] knockout: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "SRPX,GPRASP2,ANK2,VAT1L,ARNTL,CADPS,LINC00847,USP6,AKAP6,ABI3BP,CREM,SLC12A6,FSD1L,OPTN,EGR3,FGF1,AMOTL2,ST6GALNAC3,SYT17,GRB10,HMGCL,TAGLN3,NCAM2,BCAS3,PTPRH,TUG1,KLHDC8A,SH3BGR,WDR47,NAPB,LMBRD1,SPATA7,SST,PJA1,TRIM2,BEX4,TUBB2A,UCHL1,ZNF711,ZNF540,RNF103" Coexpression M7453 Genes down-regulated in CD4 [GeneID=920] T cells treated with TGF beta and IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "ACTN1,MADD,ARRB1,ARRB2,C5,CCPG1,RCBTB2,TPP1,IPCEF1,MYADM,RIPOR2,ZFYVE16,DAPK1,KLHL3,SLC12A6,RASGRP2,FAM198B,GABBR1,SEPT9,ADAM28,TTYH2,MITF,MSR1,NFE2L2,MARCH1,RNASE1,LRRK2,RTN1,MRAS,CCDC88A,SLC37A2,TBL1X,KIAA0930,ARHGAP9,SLC44A1,TLR4,NPL,SSBP2,WIPF1,WNT7A,NLRP3" Coexpression M3106 Genes up-regulated in comparison of naive T cells versus central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "ASIC1,KLHL13,PITPNM2,APBA2,LGR5,SFMBT2,SLC2A11,ATP6V0A1,DDR1,SCARB1,NOG,RIPOR2,SNPH,ARMCX2,C8orf37,NBEA,NEURL4,RAPGEF6,ZNF496,LINC01550,HSF2,IL6ST,MEST,DNHD1,SLC11A2,NUCB2,OCRL,RETREG1,LRRN3,CEP41,DCHS2,TUG1,BEND5,GAL3ST4,SATB1,CNKSR2,RNF175,PRRT1,TOM1L2,CIAPIN1,AMN1" Coexpression M5455 Genes up-regulated in comparison of mast cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "NDRG2,MYH7B,ARNTL,MARCH3,BID,CAST,RCBTB2,CLCN3,TPP1,ABI3BP,SOCS5,ZNF804A,PCOLCE2,EXTL2,CHST15,FOLR2,ATP6V1H,GALC,GLUL,GRB10,GSTT2,HP,MEIS2,MID1,AFF1,SMIM7,PTK2,PTX3,SUPT20H,R3HDM2,EPN2,ZKSCAN3,FAIM2,LMBRD1,SAMSN1,SST,CAMTA1,PCDHGB6,HEY1,TPM1,TUBB2A" Coexpression M4142 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 7.40E-05 8.40E-01 2.06E-03 2.04E-02 41 199 "CLK4,KDM5D,NDRG2,SPOP,APAF1,CHRD,ATP2A2,RGS9,HCN2,CARS,CFL2,PPT2,HECTD1,TBPL1,BOC,ZFYVE16,RUSC2,DPYSL2,FEM1B,CALCRL,ACSL4,SYNCRIP,UFM1,GABRG2,TRAF3IP2,FICD,ITPKB,JAK2,OPA1,P2RX7,PDPK1,GPR85,PMP22,QRICH1,USP47,RAD17,SALL1,SH3BP2,SLC6A8,ITPRID2,SATB2" Coexpression 18425577-TableS3b Human Breast_Creighton09_90genes GeneSigDB 7.42E-05 8.42E-01 2.06E-03 2.04E-02 21 77 "NME5,C1QTNF3,SPARCL1,APBB2,ZSCAN18,ADGRB2,CAST,CRY2,LRRC17,IL6ST,LAMA2,MAPT,NOVA1,QDPR,ZC3H14,SYBU,ZNF415,ZNF177,ZSCAN26,DNALI1,NAV3" Coexpression M6700 Genes up-regulated in endothelial cells: interferon alpha versus interferon beta. MSigDB C7: Immunologic Signatures (v6.0) 7.54E-05 8.56E-01 2.09E-03 2.07E-02 36 167 "ARNTL,MARCH3,DPY19L3,GPR146,DDR1,LARGE1,RCBTB2,PLEKHB1,FBXO7,VAX2,CNN3,CRMP1,DGKG,ARMCX2,NR1D2,NCALD,ST6GALNAC3,ABLIM2,GGT5,TTBK1,TDRKH,ITGA7,KIT,SERPINI1,JAKMIP1,PRKACB,PRKCB,SLC26A11,BCAS3,RASA3,ABTB1,SYNE2,SYNPO2,AMACR,MEIS3,KLHDC1" Coexpression 20058202-Table4 Human StemCells_Secco09_28genes GeneSigDB 7.72E-05 8.77E-01 2.10E-03 2.08E-02 11 27 "BCHE,NRP2,RIMS2,FLT1,ST6GALNAC3,IQGAP2,PID1,RASGRF2,LIMCH1,SYNPO2,HRASLS" Coexpression 18927307-tableS2 Human Colon_Allen08_357genes GeneSigDB 7.74E-05 8.79E-01 2.10E-03 2.08E-02 47 239 "AGT,CDC42BPA,MAP4K3,DST,CACNA1I,KRIT1,USP6,CLGN,NCOR1,KIAA0040,CTH,CDON,FARSB,YAF2,PAN3,DLC1,POLK,UBE2E3,DCTN2,PDLIM5,FYB1,LOXL3,TPPP,FRMD5,RBPJ,HECTD2,MATN2,MBNL1,MBP,ING3,PPP3CA,CNNM2,SAMD9,PTK2,PTPRG,SETD5,SGK1,BTBD3,NBPF1,POGZ,DIP2A,SYT1,ANKRD28,TCF12,CABIN1,ZBTB14,TRIM9" Coexpression M4716 "Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.74E-05 8.79E-01 2.10E-03 2.08E-02 47 239 "ACHE,STX16,SYNJ2,CAMK2G,ARHGEF2,CDR1,CCPG1,CLTB,PCYT1B,AKAP6,CREM,ABCG1,LRIG1,SUSD5,CTH,SPATA2,KIAA0319,DYNC1I1,DTNA,TOM1,DNAJB6,EIF5,EPB41,FLNC,IL6R,ITGA7,LMO2,MAP2,MEST,KITLG,PCSK1,SMOX,MBOAT7,MAPK10,SNRK,PTPRN,HSPA4L,ABLIM3,SLC12A4,SPP1,TSPYL2,NSFL1C,JMJD6,AGTPBP1,KIAA0930,NACC2,UBE2H" Coexpression M8189 Genes down-regulated in double positive thymocytes from OT-2 transgenic mice: control versus injected with agonist peptide. MSigDB C7: Immunologic Signatures (v6.0) 7.76E-05 8.82E-01 2.10E-03 2.08E-02 38 180 "ADD1,ALCAM,NCOA1,ATP6V0A1,DOCK11,AP1M1,CACNA1I,MAP4K4,ANKRD44,CSNK1G3,MYADM,RIPOR2,SNX29,FRY,RASGRP2,PTK2B,CHST15,SPSB4,RAPGEF6,DCLK2,ADAMTS6,BACH2,LMO2,MEF2C,LRP12,PPP3CA,SATB1,RASA3,SGK1,SH3BP2,ST6GAL1,SMARCC2,LMBRD1,CDK19,DNAJC9,SSBP2,RICTOR,TUBA1A" Coexpression M8906 Genes down-regulated in CD4 [GeneID=920] T cells versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 7.76E-05 8.82E-01 2.10E-03 2.08E-02 38 180 "PCDH19,OSBPL1A,APLP1,TNRC6C,NCOA1,ATP6V0A1,RIPK1,CLTB,NCOR1,MYADM,SEC16A,CPEB2,DTNB,E2F5,SNX29,EIF1,GLUL,GPD2,TPPP,IRAK3,KIT,LIG4,MITF,PLEC,CCDC112,ANKRD6,ELMO2,TTC17,KDM4B,GLT8D1,DIP2A,TACC1,IQCE,SLC44A1,PPP1R3F,MARCH8,KAT6A,SPATA13" Coexpression 17430594-table3 Human Prostate_Chandran07_208genes GeneSigDB 7.80E-05 8.86E-01 2.10E-03 2.08E-02 31 136 "AXIN2,EP400,PKP4,EPB41L5,BCAS1,NCOA1,ALDH7A1,AZGP1,BMP7,CD38,MAP4K4,BOC,DAPK1,EGR3,EIF5,MRVI1,PDLIM5,CELF1,GPR75,GSTT2,HBA1,LSAMP,MN1,NBL1,NEFH,PTN,FHOD3,CPEB4,SPP1,SYNPO2,UBE2H" Coexpression M9243 Genes down-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]. MSigDB C7: Immunologic Signatures (v6.0) 7.85E-05 8.92E-01 2.10E-03 2.08E-02 40 193 "ABHD6,CEP126,APAF1,EPB41L5,BCAS1,ZSCAN18,ZBTB10,DOCK11,HIP1R,ARHGEF2,CDC42BPB,PHF14,HDAC9,TBC1D5,SCRN1,SPOCK2,GIT2,ELMSAN1,DMD,DOCK2,EBI3,IQCG,AHDC1,PSIP1,MAP4K5,SYNPO,ZNF678,KPNA5,MYO9A,NTRK3,POU6F1,PPP2R5E,PTK2,TMEM260,KHDRBS2,MYCBP2,FBXW11,CYB561A3,ZNF610,LAT2" Coexpression M2505 Transcripts bound by CELF1 [GeneID=10658] in HeLa cells (cervical carcinoma). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.95E-05 9.03E-01 2.10E-03 2.08E-02 79 463 "FMNL2,BID,LDLRAD4,VXN,RUNX1T1,METTL6,CERS5,CBFA2T2,L3MBTL4,LOC730101,CFL2,ARHGAP22,STOML1,CSF1R,CSNK1E,APPL1,BOC,TCAF1,BRINP1,EEF1D,ENPP6,ANKMY1,ARMCX1,TBC1D16,KAT8,MAD2L2,SEC23B,AFF2,NBEA,UFM1,OGA,GALC,SYT17,ADAM28,GGT7,ZNF276,STON1,GRIK4,CACFD1,GSN,MAP4K5,ZNF678,ITGA7,KCNB1,CAMK2N2,MBNL1,MBP,MMP16,NOVA1,PLEC,SMOX,SMIM7,PPP3CC,EPDR1,PIGG,PTPRE,PTPRN2,MARCH1,FIGN,RGS3,SLC25A36,CHD9,KANSL3,TTC17,IFT122,NFASC,MPRIP,TBL1X,USP22,PCDHGC5,DOCK9,NSD1,FRYL,NACC2,LRRC8A,NAV3,HNRNPA3,RNF170,SOCS4" Coexpression 17952122-GeneList Human Breast_Vecchi08_792genes GeneSigDB 8.19E-05 9.31E-01 2.10E-03 2.08E-02 91 551 "OSBPL8,SPARCL1,SRPX,BBOX1,ZSCAN18,DOCK11,AZGP1,PROM1,DST,RAB29,IL33,CA12,CLGN,CHN1,SLIT2,LY86,CNN3,RBM39,VCAN,BOC,RIPOR2,HEPH,GSDME,SEC16A,CHRDL1,ECM2,EDIL3,EDNRA,RASGRP1,LRRC17,ETV1,RAPGEF6,IQGAP2,SEPT9,HPGDS,TOX3,FERMT2,PSIP1,HBA1,HNMT,IRF8,IGF1,KIF2A,KIT,LAMP2,PIK3AP1,MBNL1,MBP,MEF2C,NBL1,NELL2,CLDN11,PDE4B,GNG2,ZFYVE21,PCDH18,PMP22,PPP3CA,RASGEF1B,PRKACB,PRKCB,VPS13C,PTN,RGS4,PNMA8A,SATB1,SGK1,ST6GAL1,ARHGEF40,SMARCA4,KDM4B,FNBP1,DOK5,MYCBP2,SPP1,SAMSN1,ERBIN,TACC1,ANKRD12,TBL1X,TCF4,DMXL2,ZEB1,PUM2,FRYL,HEY1,TPM1,VSNL1,REEP1,SLC38A1,TUBA1A" Coexpression 17823660-TableS2 Human Viral_Urosevic07_495genes GeneSigDB 8.21E-05 9.33E-01 2.10E-03 2.08E-02 77 449 "SRPX,BBOX1,ANK2,DYNLL1,DST,CA12,DDR1,CBR1,CD86,LARGE1,UBE2L6,CLTB,LY86,ARHGEF6,MYRIP,ENTPD4,CSF2RA,PDE4DIP,SNPH,DAPK1,HEPH,RHOBTB1,SV2B,CHRDL1,DNM1,ECM2,DNAJB6,EIF4G1,EIF4G2,TENM1,TNK2,ELN,LRRC17,RASGRP2,NCALD,F5,F8,ABCA8,FGFR1,FHL1,FOLR2,KHDRBS3,ADAM28,GPD1,GPER1,STMN2,GSTM5,PADI2,HMGCR,IFI16,IGF1,INPP1,ITPKB,LAMA2,MAP2,MAP4,MX1,MYO7A,NOVA1,NTRK2,NTRK3,PLIN1,PPP2R5E,RELN,PTH1R,PTPN13,RNASE1,MEG3,RTN1,ST8SIA1,ZNF423,ATP10B,ANKRD28,TPM2,HIRA,UBC,VSNL1" Coexpression M4297 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] low T cells at. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ADD2,SPARCL1,LRFN1,PTCH2,AZGP1,LURAP1,MS4A7,CPNE6,SLC35F1,GPRASP1,JAKMIP2,TMCC2,SLC29A4,EGFR,SIRPB1,SCML2,C2orf88,ADAM28,GNAL,FERMT2,GPR12,TMEM121B,PCLO,MYT1,NPY,NTRK2,PLCL1,IRX1,SLC26A11,REV3L,STX1B,EPN2,ARHGEF40,SYN1,SYP,PCDHB7,ZFPM2,FSTL5,ADAMTS9,NLRP3,IFT88" Coexpression M5024 Genes down-regulated in comparison of SP1 thymocytes versus SP2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "NDRG3,ADORA1,ARHGAP20,AMPD3,ANK2,PKP4,ST3GAL5,CAST,CD86,CRMP1,C1QL2,CSNK1G3,EGFR,NRN1,FGF12,PSD2,FOLR2,HVCN1,KHDRBS3,GRM8,ADAMTS6,LRRC75A,ITGAM,LSAMP,MAP2,IGSF11,TMIE,PPP3CC,PTX3,RASA3,KDM4D,CPEB4,SOX11,SPTB,SYNE2,RGMB,UGT8,ZFP41,PPP1R3F,PARP11,KLHDC1" Coexpression M5154 Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to M.tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "GAS7,FAM131A,APOC1,CDK10,ADAM15,CALB2,CCNH,FOXN3,CHN2,LY86,HOMER3,DCAF8,GIT2,POM121,SGSM2,ABCC5,SUGP2,FOXO3,FOLH1,DCTN2,SYT17,SEPT9,STARD3,LILRA2,ACOT7,IDH3A,INPP1,ITPKB,MAN2A2,NACA,PLCB2,MAPK9,RNH1,SARS,ATXN2,SH3BGR,SPTAN1,CAMTA2,TRIO,SPHK2,UPF3A" Coexpression M5915 Genes encoding components of apical junction complex. MSigDB H: Hallmark Gene Sets (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACTN1,ADRA1B,AMH,SHROOM2,ATP1A3,ADAM23,ADAM15,SGCE,CALB2,CD86,TAOK2,SLIT2,ARHGEF6,CNTN1,COL9A1,NECTIN3,VCAN,EGFR,CERCAM,EPB41L2,SPEG,BAIAP2,EVL,FLNC,FYB1,TMEM8B,NEGR1,KCNH2,LAYN,NF1,CLDN11,NLGN3,PKD1,PPP2R2C,PTK2,NFASC,ICAM5,TRO,TSC1,SLC30A3,CADM2" Coexpression M8030 Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IFNG and TNF [GeneID=3458;7124]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACTN1,MTUS1,OSBPL8,STX16,RAB33A,DZIP3,ZFYVE16,MAML1,SPOCK2,PITPNC1,TENM1,VPS13B,SH3YL1,SEC24B,SEMA4D,FYN,ZNF276,BTN2A1,BACH2,HSPA1L,IL6R,IL6ST,MAN2A2,MARK3,NELL2,PFKFB3,ABCB1,ING3,PPM1B,LRRN3,PPP2R5E,PTK2,PCMTD2,GALNT10,SUPT20H,SLA,ATF7IP,KDM4B,ZSWIM8,ERBIN,TIAM1" Coexpression M7961 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "NDRG3,ADCY6,SORCS2,ZFYVE28,BBS2,RGS11,CA12,CAPN3,CNN3,KIAA0040,DAPK1,ALKBH8,MTX3,TOM1,PLEKHA1,EYA1,TBC1D16,KCNMB4,GPD2,NIM1K,SRSF12,MITF,AFF1,AFDN,NFIX,PFKFB2,TMIE,FITM2,RASGRF2,BEND5,CCDC82,ATP8B4,CCDC88A,TET1,EPC1,RGMB,TRIO,STXBP4,SSBP2,SGK3,AMZ1" Coexpression M3314 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "FMNL2,TMCC3,LCORL,NT5C3B,CASK,BTK,PTBP2,FAM189A2,COL9A3,ARHGEF10,CSNK1E,USP3,CD99L2,TMEM35A,ARMCX1,CORO2B,MEX3B,OGA,FYB1,CHL1,GABARAPL2,RBPJ,ETFRF1,PRKCB,PTCH1,RIPOR1,BEND5,MRAP2,FBXW7,SEC14L1,HSPA4L,SH3BP2,R3HDM2,SLC12A4,ZNF667,DIP2A,FBXW11,TCF12,TIAM1,TP53BP2,SENP7" Coexpression M293 Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from: mesenteric lymph nodes (mLN) versus spleen. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "GPRASP2,ALDH7A1,CAMK2G,KYAT1,CBFA2T2,RCBTB2,TPP1,MAGED1,ARHGEF4,SLC12A6,RASA4,CALCRL,HSPA12B,REEP2,ABCA8,RPS6KC1,PPP1R1B,FER,GTF2IRD2,GATM,NCKAP1L,RBPJ,MBP,RETREG1,MAPK7,DEF8,KLHDC8A,BTBD3,ATF7IP,MYCBP2,KLHL7,DNAJC9,TACC1,DNMBP,ARHGAP9,METTL3,TTC3,SGK3,VIPR2,KCNK12,PLD4" Coexpression M7022 Genes up-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus granulo-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "OSBPL1A,BIN1,SEMA7A,PRX,MARK4,ATP6V0A1,LDLRAD4,CERS5,MTMR7,TMEM184B,LRIG1,PDE4DIP,PUM1,SACS,WDR20,CPEB2,TSPAN5,YAF2,ACSL4,SYNCRIP,SYT3,GABBR1,GLUL,LPAR4,ATE1,RBPJ,L1CAM,LAMP2,STRN3,GDPD1,WBP1L,ZFP2,FAM102A,FAM214B,FAM126B,KDM3A,NEK4,SYP,SLC44A1,TRPS1,ZDHHC20" Coexpression M8056 Genes down-regulated in plasmacytoid dendritic cells (6 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ABCD2,FGD2,APOC2,NCOA1,BACH1,GPR146,SOCS6,ARHGAP22,TPP1,ARHGEF6,ABCG1,PHF14,PUM1,FCGRT,BAIAP2,PDLIM5,FYN,MSL3,GPR34,DDX19B,NIM1K,TM6SF1,P2RX7,PURG,PPP3CA,ZDHHC14,CHD9,R3HDM2,GKAP1,UHRF1BP1L,SULF2,TCF12,TMEM9,SSBP2,WIPF1,AGMO,MAP3K12,ITM2C,RTN4,ADAMTS10,FXR1" Coexpression M5617 "Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569] versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]." MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "SEMA7A,WASF1,DDR1,MTMR7,CD86,CD38,ARHGEF2,CACNA2D2,AHCTF1,SMARCAL1,OSBPL3,GAPVD1,INTS1,ARMCX4,POM121,TNK2,STX2,FKTN,ATP6V1H,GCNT2,GPD2,GSN,TOX2,NCKAP1L,HNMT,MSL1,PDPK1,PIK3R1,ZNF655,MAPK9,PTCH1,SGK1,FNDC3A,KANSL3,SPART,STX1A,FBXW11,ZEB1,TIAM1,UBE2H,RSPRY1" Coexpression M8541 Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "TXNDC16,ALCAM,BIN1,BTK,CD38,RAB28,LY86,ZNF385A,AKAP12,RASSF2,IST1,RCAN1,EIF4G2,ING4,SRPK3,EPB41L2,CORO2B,FCGR1A,FAM49B,CPLX2,FICD,INPP1,KTN1,MEF2C,MYO5A,NCF2,NUCB2,PCSK5,ZDHHC14,RGS4,SLC25A36,ZNF532,SAFB,MAPK12,MYCBP2,SYPL1,TCF4,SLC44A1,TK2,C9orf85,EVI5" Coexpression M7998 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACTN1,RNF150,C5,CAST,SYNGR3,PLEKHB1,NDST3,CDC42BPB,CSF2RA,UBXN2A,PHF14,CYBB,MYADM,SCRN1,AIF1L,DBN1,CDON,DOCK2,E2F5,EZH1,LPAR4,PTPRT,FICD,IGFBPL1,IL6ST,MYO9A,PCDH8,PRKAB2,MTMR10,PTPRE,PPM1E,RCOR3,STAC2,ANKRD12,EXOC7,SIK3,ATP6V0E2,AMZ1,RNF103,FXR1,SENP7" Coexpression M5909 Genes involved in development of skeletal muscle (myogenesis). MSigDB H: Hallmark Gene Sets (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACHE,BIN1,PPFIA4,MYOM1,CAMK2B,LARGE1,MYL6B,CNN3,PICK1,SH2B1,PDE4DIP,DMD,DMPK,DTNA,SPEG,FHL1,GAA,GNAO1,GSN,GABARAPL2,IGF1,ITGA7,KCNH2,KIFC3,LAMA2,MEF2C,MYH3,PGAM2,FXYD1,SCHIP1,PKIA,MAPK12,MRAS,SH3BGR,SLC6A8,SIRT2,SPTAN1,ST5,TPM2,TSC2,REEP1" Coexpression M7155 Genes down-regulated in CD4 [GeneID=920] T cells versus follicular helper CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "NDRG3,SFMBT2,ARRB2,RGS11,CAST,RCBTB2,CRMP1,ARHGEF4,DPYSL2,CALCRL,MEX3B,SDCBP2,ERAP1,MTHFD2,SEPT9,KCNMB4,GPR34,ZBTB45,ZDHHC15,RBPJ,IL6R,IL6ST,INPP1,INPP5B,SLC35G1,STXBP5,L1CAM,P2RX7,TMIE,GPSM2,SMOX,SLC25A23,OXR1,RNASEL,ATP8B4,RCOR3,STX1A,RHBDL3,RUNDC3B,MEIS3,ADAMTS10" Coexpression M4980 Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 0 versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "KIAA1324,ABCD2,MARCH3,WASF1,RUNX1T1,CDH2,TAOK2,TPP1,ENTPD4,KIAA0040,IP6K1,MAMLD1,EGFR,TENM1,NCALD,SCARA3,DENND2A,SIGLEC8,GHR,LYVE1,RNFT2,SYNPO,KCND2,NFYA,ENPP2,ABCB1,PKIA,PRODH,MTMR10,PTPN13,C1orf109,GAL3ST4,SYBU,RCOR3,MBD5,KANK1,ANKRD12,TCF4,UGT8,WNT7A,ZNF37BP" Coexpression M4571 Genes down-regulated in comparison of thymic progenitors versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACTN1,NDRG2,ADCY6,ADRB2,TXNDC16,ALDH7A1,CBLN1,CACNA2D2,RAB33A,DAPK1,ABCC5,ANKRD46,HEYL,PDLIM5,FYB1,FICD,AGFG1,MBP,TM6SF1,MIA2,SETD4,TMEM38A,PRKCB,SNRK,PTPN13,PTPRO,RASGRF1,HUNK,SATB1,CDK5RAP2,SYNE2,SLC37A2,DNMBP,SIN3B,CUX2,SYNE1,ARHGAP9,PRRT1,CDK20,TUBB2A,EVI5" Coexpression M9778 Genes up-regulated in resting CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ABCD2,ZNF687,ARRB1,MARCH3,ATP1A1,MYOM1,PROM1,CBR1,SYNGR3,MS4A7,TPP1,MAGED1,C2CD2,ABCG1,AATK,DBI,ABCC5,SEZ6L2,OPTN,ADGRV1,FCGRT,DOT1L,ALDH1L1,GLI2,GPD1,SYNPO,KCTD6,SCAMP5,MYO7A,SETD4,OCRL,PILRA,KIF7,RXRA,MRAS,SH3BP2,MAPKBP1,GLT8D1,SYNE2,PRRT1,NHSL1" Coexpression M8082 Genes up-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "UNC79,LRCH2,DDO,SFMBT2,CA8,SLIT2,HAPLN1,SEC14L5,PYGO1,SLC29A4,SEZ6L2,FGF14,SUCO,FAM49B,RAPGEF6,GPR162,ADAM28,GRIA2,FRMD5,HSF2,KCND2,GPR62,LAMP2,CNTN3,PCDH8,GPSM2,TRHDE,SEPT4,DRAM2,LRRN3,NUDT11,NEK11,BAALC,SH3GL3,NLGN1,SYP,ZFPM2,CSMD1,RICTOR,MKRN3,FSTL5" Coexpression M6927 Genes up-regulated in B lymphocytes: anti IgM versus CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ADORA2A,SPOP,N4BP2L1,SYNGR3,IPCEF1,GALNT9,KIAA0040,PNPLA8,RIPOR2,CENPL,IP6K1,ARMCX2,ANKRD46,MBNL2,ASB3,ING4,SLC43A2,SH3YL1,FOXO3,EVL,ZNF274,C15orf41,NEU3,SESN1,MSL3,CBX1,FAM69A,SFR1,NEK1,TMIE,RETREG2,OXR1,DZIP1,ST8SIA1,SLA,ZNF667,KDM4B,MTMR14,UBE2H,SPATA13,SENP7" Coexpression M8042 Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus those activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "RALGAPA1,MTUS1,SYNJ1,ST3GAL5,LRBA,CCPG1,RAB33A,BAG4,SEC31B,IPCEF1,RUBCN,GPRASP1,GAPVD1,RIPOR2,ZFYVE16,PITPNC1,ARMCX2,FBXL5,OPTN,DENND4A,TAOK3,FKTN,ZNF274,FAM69A,NELL2,OGG1,ENPP2,SERPINI1,PIK3C2A,ZNF493,MSANTD2,GTDC1,ROBO1,CCDC25,CLIP1,AP1AR,SMARCD3,TTC17,DOP1A,WIPF1,ZNF189" Coexpression M6570 Genes down-regulated in monocyte-derived dendritic cells: AM580 [PubChem=2126] versus rosiglitazone and AM580 [PubChem=77999;2126]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ADCY6,ADD1,BEND6,PHYHD1,ATP1B3,CFLAR,ARHGEF1,RCBTB2,PITPNC1,USP3,RASGRP2,ST3GAL6,FCGRT,HVCN1,B4GALNT1,RAPGEF6,ZNF274,GPR34,STMN2,SPACA9,IRAK3,DDX19B,FAM69A,L1CAM,MATN2,FXYD7,SFR1,SERPINI1,PIK3R1,ATP8B4,DGLUCY,GALNT10,RASA3,CABCOCO1,IZUMO4,STX1A,ARHGAP9,RELL2,LRRC8A,PIK3R5,FRMD6" Coexpression M9205 Genes up-regulated in CD8 T cells: wildtype versus STAT1 [GeneID=6772] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "AS3MT,ACTN1,ADCY6,TMCC3,ADD1,ESYT2,TBC1D14,GPRASP2,ZFYVE28,NCOA1,DOCK11,LRBA,ARHGAP33,ARHGEF10,SIPA1L1,KIAA0040,RIPOR2,DAPK1,NYAP1,FRY,EIF1,F8,ARMCX1,BACH2,ZDHHC15,NIM1K,KCNH2,MX1,PIK3C2A,TMIE,LRP12,PRKCB,MAPK7,CEP97,SATB1,RASA3,DZIP1,TMCC1,POGZ,WBP2,TUBB2A" Coexpression M8052 Genes down-regulated in T cells: control versus TX527 (hypocalemic analog of 25-hydroxyvitamin D3 [PubChem=1593]). MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "MTA3,ALCAM,ABCD2,MAP4K3,ST3GAL5,FOXN3,C1QL2,ABCG1,CST3,DCAF4,FAM107B,PLXNC1,EXTL2,EYA1,TAOK3,GALC,INPP5K,ACSS1,SESN1,GPR34,PADI2,KTN1,GPR155,CDK18,DRAM2,RASGEF1B,OXR1,ATXN7,SUPT20H,CCDC88A,USP33,FAM219A,MYCBP2,ERBIN,CEP68,DNAJC9,TSC1,WIPF1,GDPD5,TMEM178A,FRMD6" Coexpression M9447 Genes up-regulated in splenocytes: control versus infected with Baki-1 MuLV virus. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "BRAP,PWWP2A,MTA3,MAP4K3,STX16,DOCK11,CAST,CBFA2T2,CRLF1,CNOT8,IPCEF1,SIPA1L1,UBXN2A,CYBB,ARHGAP24,PITPNC1,EIF1,TAOK3,AK8,FAM49B,SARAF,FYN,INPP5K,RAB30,COQ10A,IL6R,IL6ST,MYO6,NCF2,P2RX7,STRN3,PPP3CA,BCAS3,TUG1,MYO18A,CPEB4,ZBTB43,DICER1,TSC1,TUBA1A,TTC7A" Coexpression M8048 Genes down-regulated in CD8 T cells: control versus stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "RNF150,MTA3,ABCD2,STX16,LRBA,RCBTB2,SOCS6,PLXNA4,GAPVD1,PITPNC1,PLXNC1,PLEKHA1,VPS26C,TLR7,TUBA1B,GTF2IRD2,POLK,PCYOX1,POMT1,PSIP1,STMN1,LMO2,MIA2,PTOV1,CHAMP1,PURG,MAPK3,CNNM2,CYBC1,UBR7,GKAP1,ABTB1,SP4,CDK19,CLASP2,DNMBP,AKTIP,CBX5,UBE2H,PDSS2,FRMD6" Coexpression M4585 Genes down-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ADRB2,AMPH,KCNAB2,CASK,ARNTL,BID,CA8,CAPN3,CBLN1,LY86,TBPL1,CLVS1,RACK1,FDFT1,SCARA3,PDLIM5,GPR34,GRB10,FICD,AGFG1,KIFC3,LYPLAL1,MEIS1,MMP17,SETD4,PGAM2,SEPT4,PKIA,APTX,SNRK,PTPN13,PTPRO,SUSD4,CRTAC1,HUNK,SH3GL3,CDK5RAP2,KLHL7,CUX2,BEX4,PCBP4" Coexpression M5229 Genes up-regulated in comparison of dendritic cells (DC) exposed to 5 worms/well B. malayi versus DC exposed to M. tuberculosis MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ASIC1,ADD1,GAS7,FAM131A,APOC1,ADAM15,CCNH,CHN2,RAB33A,CLTB,LY86,COX4I1,NCOR2,SGSM2,ABCC5,SUGP2,FCGRT,FOXO3,FOLH1,SRCAP,GFRA2,IDH3A,INPP1,ITGAM,LMO2,MAN2A2,PTOV1,NACA,PCSK5,PLCB2,RNASE1,RNH1,SGK1,SH3BGR,SEC31A,SLA,SPTAN1,CAMTA2,TBL1X,TPM1,CLIP2" Coexpression M9253 Genes down-regulated in dendritic cells: hydrogen peroxide [PubChem=784] versus diphenyleneiodonium (DPI) [PubChem=2733504]. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACADM,AQP6,BBS2,GPR146,CFLAR,MTMR2,ASIC3,ABCG1,GPRASP1,NR1D2,RASGRP1,EGR3,CALCRL,FOXO3,EVL,HVCN1,OGA,ACSS1,PPM1L,PFKFB2,ZNF655,RASGRF2,ZDHHC14,PCMTD2,ZNF354C,SATB1,ATF7IP,TET1,TMCC1,MYCBP2,ERBIN,ALG1,KIAA0930,RUNDC3B,AMACR,TSC1,PDIA2,TBC1D15,REEP1,PPP1R3F,JMJD1C" Coexpression M5729 Genes down-regulated in comparison of lymph node regulatory T cells versus lymph node conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.32E-05 9.45E-01 2.10E-03 2.08E-02 41 200 "ACTN1,ADCY6,RNF150,AP2A2,NUMB,GPR146,CARS,PPT2,CNN3,CSNK1E,PLXNA4,GUCD1,TOM1,RASGRP2,CAMKK2,GSN,GATD1,HECTD2,LSS,MN1,NFE2L2,NTRK3,SETD4,TREM2,TMIE,GPSM2,SLC26A11,ATP8B4,EMID1,CLIP1,SATB1,SGK1,FAM102A,SYNE1,PIK3R5,RGMB,KCNK12,CELF4,SLC30A4,KLHDC1,AP3B2" Coexpression M19384 "Genes up-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.50E-05 9.66E-01 2.14E-03 2.12E-02 33 149 "ADD2,KIAA1324,DPP10,STK33,BCHE,BMP7,NOG,SUMF2,ARRDC4,GPHN,TMEM107,APOPT1,NSG1,GLI2,GRIA2,HNF4G,MBP,NTRK2,PCSK5,MASP1,RELN,BCAS3,PTCH1,DUSP15,RET,BAALC,TNFRSF19,ZFP2,RADIL,ZC3H13,TSPAN11,CADM2,ST8SIA2" Coexpression 19724859-Table3 Human Breast_Folgueira09_26genes GeneSigDB 8.55E-05 9.71E-01 2.15E-03 2.13E-02 9 19 "PTBP2,SPAG9,GALC,GIT1,KCTD15,METTL3,VLDLR,ZNF19,ZNF189" Coexpression M2875 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 8.78E-05 9.97E-01 2.20E-03 2.18E-02 32 143 "NME5,CALB1,CDR1,CHGB,ERC2,DOCK4,ARHGAP24,SNAP91,DYNC1I1,RCAN2,ETV1,ST3GAL6,GABRA3,TOX3,HAS2,KCNH2,KIF5A,NRCAM,PCDH8,MAPK10,RELN,PTX3,RNASE1,RTN1,SNAP25,SPP1,LMO3,SYT1,HEY1,WNT7A,MKRN3,NAV3" Coexpression M6765 Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.78E-05 9.97E-01 2.20E-03 2.18E-02 32 143 "ADD1,BCHE,GPR146,AP1M1,CSF1R,PPP6R2,HDAC9,C2CD2L,SV2B,CPEB2,DPYSL2,SNX29,FCGRT,TMEM175,ACSS1,GSN,KNDC1,KCNJ16,PDE4A,PLCB2,RPS6KA2,TMEM200C,GALNT10,PPM1E,ST6GAL1,SULF2,SYNE1,TRPM2,TSC2,SH3GLB2,KCNAB1,ADAMTS10" Coexpression M3695 Genes up-regulated in prostate cancer samples bearing the fusion of TMPRSS2 with ERG [GeneID=7113;2078]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.08E-05 1.00E+00 2.27E-03 2.25E-02 19 67 "AMPD3,CADPS,NCOA1,EIF4G3,BMPR1B,SIPA1L1,DBN1,EIF5,SH3YL1,KHDRBS3,SEPT9,GHR,RAB30,GP1BB,KCNN2,MYO6,PRKAR1B,SAFB,PCDHGB7" Coexpression M6690 Genes up-regulated in fibroblasts: interferon alpha versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 9.27E-05 1.00E+00 2.31E-03 2.29E-02 37 175 "AS3MT,HACE1,CARNS1,APAF1,GAS7,APLP1,NCOA1,LRBA,DCLK1,CRY2,CSF1,PTK2B,CHST15,MED12L,FYN,ADAMTS6,ZDHHC15,STXBP5,PIK3AP1,GPR155,XRN1,PPP3CA,BCAS3,TMEM104,PTPN13,PTPRE,RGS3,FBXW7,RXRA,SEMA6D,MAPKBP1,SAMSN1,SULF2,FRYL,SIK3,ZBTB38,GDPD5" Coexpression 18308945-Table4 Human StemCell_Huang08_120genes GeneSigDB 9.48E-05 1.00E+00 2.36E-03 2.34E-02 27 113 "PKP4,DPY19L3,SPAG9,ZMYM4,CLGN,ELN,EFCAB2,ATP2C1,ZNF605,ADGRA3,RBPJ,MEIS1,MEST,NEK1,EPDR1,RBBP8,ROBO1,BAALC,CHD9,ZNF334,ZNF667,OBSL1,TMEM9,TP53BP1,TRO,MICU3,ZNF70" Coexpression 19101988-Table2a Human Breast_Habermann09_38genes GeneSigDB 9.56E-05 1.00E+00 2.37E-03 2.35E-02 12 32 "KIAA1324,ALCAM,GREB1,ARMCX2,DMTF1,ARRDC4,EVL,CSPG5,SYT17,IPO5,PKD1,DNALI1" Coexpression M357 Genes up-regulated in wildtype B cells versus BAFF-transgenic (over-express TNFSF13B [GeneID=10673]) B cells from lymph node. MSigDB C7: Immunologic Signatures (v6.0) 9.75E-05 1.00E+00 2.41E-03 2.39E-02 36 169 "SYNJ1,MTMR3,DCAF8,HDAC4,DAPK3,DPYSL2,FRY,STX2,SEMA4D,TMEM107,STAU2,GABRG2,SEPT9,GPD2,MAP4K5,NCKAP1L,ITPKB,L1CAM,MATN2,PDE4D,PDPK1,ZDHHC8,RETREG2,GTDC1,PCMTD2,ADAL,SBF1,CASC3,FAM102A,WDR37,CCDC88A,TET1,TTBK2,ZC3H4,LRRC8A,CPNE4" Coexpression M13008 "Genes exclusively down-regulated in fibroblasts expressing the TTD mutant form of ERCC3 [GeneID=2071], after UVC irradiation." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.78E-05 1.00E+00 2.42E-03 2.40E-02 22 84 "AMPH,CDC42BPA,DST,SYNJ2,NECTIN3,ARHGEF10,PHF14,DOCK4,DMD,VPS13B,AHDC1,MALT1,HAS2,MIA2,MITF,PIK3C2A,WDR37,TMCC1,DOCK9,FAM155A,INTS3,NAV3" Coexpression 16042785-tableS4 Human Prostate_Oudes05_66genes GeneSigDB 9.88E-05 1.00E+00 2.44E-03 2.41E-02 18 62 "DDO,ZSCAN18,ZNF555,CPS1,CNTNAP2,DTNA,TSPAN5,MBNL2,ETV1,PCLO,PARD3B,JAKMIP1,ZIK1,MARCH1,SUSD4,ZSWIM8,MCF2L,SPHK2" Coexpression M2618 Genes transiently induced only by the first pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-04 1.00E+00 2.48E-03 2.46E-02 255 1838 "PTCHD1,ZNF608,MTUS1,KLHL13,RTL9,OSBPL1A,SORCS2,BBOX1,FAM135A,LRCH2,CCDC146,MAP4K3,KCNAB2,APBB2,APOC1,APOC2,SEMA4G,PPP4R4,RGS20,ARRB2,CDK13,ASPA,N4BP2L1,ATP6V1G2,RIPK1,BBS2,CFLAR,PRMT9,C5,CACNA1B,DDR1,CAMK2G,ZNF501,USP6,USP2,C1orf52,KCNAB3,DCLK1,TIGD7,CCPG1,FOXN3,CHN1,B4GALT6,C4orf33,COL4A5,TBPL1,NECTIN3,FAM171B,C2CD2,CREM,TRIM69,CRYM,CSF1,LRIG1,LRRC3B,PDE4DIP,CNTNAP2,DZIP3,CTH,RIMS2,RUBCN,HDAC9,ARHGAP24,ZFYVE16,KIAA0586,DAPK1,DNAL1,ARMCX4,SPATA2,ZBTB24,HEPH,MYEF2,SLC12A6,TOM1,SNX29,EDNRB,ANKRD46,EEF1D,FSD1L,CELSR3,RASA4,PLEKHA1,ING4,CERCAM,MRNIP,C8orf37,USPL1,MTSS1L,SLC43A2,STX2,CDKL3,RRAGB,NRN1,F5,NSRP1,ZSCAN30,FECH,FER,BAIAP2,EFCAB2,NBEA,POMT1,UFM1,USP21,FYB1,GAD1,ZNF234,ZNF274,LRRC37A6P,BRD8,RAB30,GPR75,GNAL,GPR37,CNTRL,DIDO1,PLPP7,GSN,GSTM5,ZBTB49,BVES,AP4S1,PSIP1,MIER3,SYNPO,HSPA1L,INPP1,INPP5B,CREG2,KIF5A,LIG4,MAP2,MAP6,MEIS1,KCTD6,MIA2,KITLG,MID1,POC1B,MN1,MOV10,TAGLN3,NFE2L2,SLC11A2,KSR2,PCSK5,CDK18,PDE4D,PDPK1,TMOD2,PFKFB4,SERPINI1,NALCN,PIK3R1,ZNF655,RETREG1,PLCD1,ZNF426,MTRF1L,PLXNB1,LRP12,MINDY2,PPM1B,PPP3CC,MAPK10,FITM2,PSD,WBP1L,GDPD2,ZSCAN32,PTPN13,ZSCAN2,ZNF615,ZNF844,FAT4,FAM184A,RGS12,RNASEL,C12orf49,YY1AP1,PCMTD2,NEK11,FBXW7,TCP11L1,ABCA11P,CLIP1,CCDC112,S100B,DGLUCY,SEMA6D,ATXN7,SCN7A,FNIP1,ARX,CPEB3,ST6GAL1,WDR47,SLC14A1,NAPB,ATF7IP,CPEB4,SMARCD3,INTS9,MBD5,KIF13A,CMTR2,SNRPN,TMCC1,TRERF1,KDM3A,LHPP,PBLD,THSD1,ZC4H2,ZSCAN29,APOM,CEP68,ADHFE1,PHLDB1,NECAB1,JMJD6,SYNE2,PLCB1,SYT1,MMS19,ADGRL3,AGTPBP1,TCF4,FAM200B,KAT6B,TP53BP2,LRRC24,TUBB2A,GORASP1,FLRT2,TOM1L2,SLC47A2,ZNF23,ZNF28,INTS3,MAP3K12,EMSY,RNF103,NAV3,TRIM16L,PLSCR4,AMN1,DOCK8,MARCH8,ZNF37BP,FBXO36,JMJD1C,RNF146,GAN,SENP7" Coexpression 15466185-Table4 Human StemCell_Upender04_17genes GeneSigDB 1.02E-04 1.00E+00 2.49E-03 2.47E-02 7 12 "CCK,NECTIN3,CLDN11,SERPINI1,PTPRG,CLSTN2,ADAMTS9" Coexpression 21220101-FigureS6 Mouse StemCell_Newbern11_209genes GeneSigDB 1.02E-04 1.00E+00 2.50E-03 2.48E-02 35 163 "SYT13,FGD2,VAT1L,CAMK2B,PLEKHB1,MS4A7,GALNT9,DAPK1,DLX1,ETV1,CHST15,ATP2C1,MEGF10,CPLX2,PCDH17,KNDC1,INSM1,MBP,MID1,NBL1,NELL2,NPY,NPR2,NTRK2,ENPP2,DUSP26,PKM,RANBP3L,SPATA7,RGL1,SYN2,TAF6,TPM2,VGF,KCNAB1" Coexpression M8819 Genes up-regulated in Foxp3-ires-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background. MSigDB C7: Immunologic Signatures (v6.0) 1.04E-04 1.00E+00 2.54E-03 2.52E-02 31 138 "WDR35,NCOA1,ATP1A3,SYNJ1,SYNJ2,JAZF1,PLCXD3,ARHGAP24,TSPAN5,CHST15,GUCY1A1,GUCY1B1,SYNPO,IRF8,SCIN,INPP5B,LIMS1,SYTL4,HECTD2,NF1,NTRK3,CNNM2,PTCH1,PEX2,SH3GL3,FAM81A,GLT8D1,GPRIN3,HEY1,TMEM63C,IFT88" Coexpression M7876 Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.11E-04 1.00E+00 2.69E-03 2.67E-02 28 120 "IGDCC4,ZSCAN18,JAZF1,CA8,CACNB4,CH25H,NRXN3,FAM19A5,CNTN1,MYEF2,DMPK,TUBA8,GFRA2,SOX21,CHIC1,NPTX1,NRCAM,PDZRN4,SH3KBP1,LRRN3,PKIA,TMEM255A,RASA3,ANKRD6,SLC14A1,LIMCH1,SYNE1,FLRT2" Coexpression M6316 Genes up-regulated in macrophages: control versus Sendai virus infection. MSigDB C7: Immunologic Signatures (v6.0) 1.11E-04 1.00E+00 2.69E-03 2.67E-02 36 170 "ACTN1,ADCY6,OSBPL1A,SEMA6A,BBOX1,PITPNM2,TMEM108,GPR146,MAP4K4,ABCG1,SIPA1L1,HDAC4,DPP6,RASGRP1,CALCRL,CHST15,RAPGEF6,SYNPO,LRRC75A,CLEC18A,ADAM11,LRP1B,PIK3C2A,TMIE,SATB1,ST6GAL1,ST8SIA1,TET1,TRERF1,CLASP2,TBL1X,TIAM1,LRRC8A,TUBB2A,ZIC1,JMJD1C" Coexpression 18405367-Table2a Human StemCell_Tondreau08_58genes GeneSigDB 1.11E-04 1.00E+00 2.70E-03 2.67E-02 16 52 "CASK,NRP2,SLC16A4,CLCN3,SNCAIP,GOLT1B,ETV1,ACSL4,SYNCRIP,GALNT15,NEGR1,SYTL4,PCSK1,PDE4B,CDK5RAP2,NETO2" Coexpression 11559565-Table3 Human Brain_Rickman01_53genes GeneSigDB 1.11E-04 1.00E+00 2.70E-03 2.67E-02 16 52 "RUNX1T1,COL9A1,COL9A3,VCAN,DTNA,EGR3,TNK2,GRIA2,NTRK3,OXTR,PDE4B,PIK3R1,PRKACB,SGK1,SNCA,TIMP4" Coexpression M2633 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable EGFR [Gene ID=1956]. MSigDB C6: Oncogenic Signatures (v6.0) 1.12E-04 1.00E+00 2.70E-03 2.68E-02 40 196 "CLK4,KIAA1324,APBB2,ZSCAN18,MPDZ,CALB2,PTBP2,KRIT1,CHN1,COL9A3,GREB1,TCAF1,TSPAN5,RASGRP1,EGR3,EPB41L2,ARMCX1,DLC1,PCYOX1,GALC,GPER1,GRB10,ELOVL5,MATN2,PRKACB,ELOVL2,PCMTD2,HSPA4L,ATF7IP,SOX3,PEG10,ITPRID2,DMXL2,SATB2,METTL3,HIRA,SGK3,WIPF1,SH3GLB2,MFF" Coexpression M17173 "Genes up-regulated in the nucleus accumbens (a major reward center in brain) 8 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.14E-04 1.00E+00 2.75E-03 2.73E-02 15 47 "ADORA2A,HCN2,CAMK2A,USP2,ARHGEF2,CDH2,CRY2,RASSF2,TSPAN5,GNAO1,GRIA2,KCNB1,KIF5A,PRKCB,ST6GALNAC6" Coexpression M2157 Genes down-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.18E-04 1.00E+00 2.84E-03 2.82E-02 84 505 "ACHE,ALCAM,CDC42BPA,SEMA7A,EPB41L5,BCAS1,SFMBT2,DOCK11,BMP7,LDLRAD4,CAST,USP2,CDH2,DCLK1,SLIT2,ABCG2,QKI,MAP4K4,FAM171B,ABCG1,DZIP3,PNPLA8,FAM131B,MYADM,DAPK3,DBN1,CPEB2,RCAN1,ABCC5,EDN1,KLHL5,OPTN,PHF20L1,AASS,EPB41,EPB41L2,ERBB2,ADGRV1,RPS6KC1,SH3YL1,TAOK3,NBEA,PDLIM5,FAM49B,TRIM16,FERMT2,LNX1,STON1,GPR37,UBE2QL1,SYNPO,KIFC3,L1CAM,NCOA7,MAP2,MATN2,MID1,MMP16,MYO6,RTL5,NCF2,PCDH9,XRN1,SCHIP1,PPP3CC,ZSCAN2,FAT4,GALNT10,ABLIM3,CPEB4,INAVA,LIMCH1,LMBRD1,KDM3A,RGL1,PHLDB1,TACC1,MTCL1,BEX4,UBE2H,TOM1L2,EVI5,MSRB3,FRMD6" Coexpression M19025 Up-regulated genes distinguishing in multiple myeloma (MM) samples with higher expression of TACI [GeneID=23495]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.21E-04 1.00E+00 2.91E-03 2.89E-02 71 411 "LTBP4,AMPH,PI16,APAF1,APOC2,PPFIA3,SEMA4G,PRX,ARRB1,CDK13,AZGP1,NRP2,CACNA1I,DDR1,CALB2,CAMK2B,CLDN10,LARGE1,FAM189A2,CCDC151,PICK1,AKAP7,COL11A2,CRYM,KIAA0586,SGSM2,HS3ST2,DUSP9,MAMLD1,SEZ6L2,EGFR,ETV1,HPCAL4,FOXF2,NOP56,GABBR1,GGTA1P,GNG4,GPR12,GRB10,GSTM5,KCNB1,KCNH2,KIF5A,MBP,ADAM11,MITF,AFDN,MPP2,GIT1,SAMD14,LINC00672,NF1,NTRK3,GNG2,FA2H,MAPK10,GTDC1,RGS12,RNASE1,KCNIP1,LRFN5,PKNOX2,SLC6A8,SNCA,TSNAXIP1,SOX15,SSTR2,TACR1,PIK3R5,FLRT2" Coexpression M7002 Genes down-regulated in B lymphocytes: ZFX [GeneID=7543] knockout versus wildtype cells stimulated by anti-IgM for 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.22E-04 1.00E+00 2.92E-03 2.90E-02 34 158 "AKAP5,LRIG1,SNX29,RASGRP1,PLEKHA1,SLC43A2,CHST15,EVL,ZMAT1,ACSS1,TDRKH,BACH2,HECTD2,MBP,NTRK3,PKD1,PLCB2,JAKMIP1,EML5,ST6GAL1,DZIP1,ST8SIA1,TET1,MBD5,CEP68,MGRN1,SYNE1,KAT6B,SSBP2,TTC3,TOM1L2,MAP3K12,MPPE1,KLHDC1" Coexpression M2010 Genes with high-CpG-density promoters (HCP) bearing the bivalent histone H3 trimethylation mark at K4 and K27 (H3K4me3 and H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.23E-04 1.00E+00 2.93E-03 2.91E-02 42 210 "CCDC85A,ADORA1,UNC5A,SLC24A4,SEMA7A,CBLN1,NOG,MYRIP,RGS6,PLXNA4,CELSR3,FGF11,FOXF2,FLT1,ABLIM2,GAD1,GNAL,NXPH3,FRMD5,KNDC1,NEFM,PCDH8,PLTP,RASGEF1B,RELN,LAMA1,PTPRN2,RASGRF1,RET,KLHDC8A,SATB1,NMNAT2,TACR1,CHST8,CDH22,CSMD1,VGF,KCNK12,ELFN1,WNK2,AP3B2,ST8SIA2" Coexpression M1714 Genes enriched in oligodendrocytes in the adult mouse brain identified through correlation-based searches seeded with the oligodendrocyte cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.25E-04 1.00E+00 2.97E-03 2.94E-02 20 74 "HCN2,MYRF,PLEKHB1,QKI,AATK,ARHGEF10,TPPP3,GATM,GPR37,GSN,TTYH2,MBP,NRBP2,SEPT4,FA2H,QDPR,SGK1,WSCD1,SLC44A1,UGT8" Coexpression M10664 Genes up-regulated in MFCF-7 cells (breast cancer) upon stable autocrine expression of HG1 [GeneID=2688]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.25E-04 1.00E+00 2.97E-03 2.94E-02 50 264 "HECW2,KIAA1324,SPARCL1,ALCAM,LGR5,NRP2,BMP7,SGCE,PRC1,ENTPD2,LRRFIP1,CFL2,CPNE6,RIMS2,DOCK2,RCAN1,PHC2,ANKRD46,YAF2,LINC-PINT,MRVI1,FAM198B,ST6GALNAC3,DBF4,CBX1,GPR12,STMN2,SOX21,MUM1,INSM1,SFXN5,SCAMP5,ZNF827,SH3KBP1,HYDIN,ALG9,SARS,SATB1,CSRNP3,SNCA,SPATA7,PEG10,ARHGAP26,NECAB1,TK2,PRRT1,TRPM2,TSC1,UGT8,TOM1L2" Coexpression M4431 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus naive B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.25E-04 1.00E+00 2.97E-03 2.94E-02 40 197 "PARG,MARCH3,SLC4A4,ATP6V0A1,BTK,DDR1,USP2,LARGE1,LY86,CNR1,SOCS5,HDAC9,MYEF2,TIAM2,RHOBTB1,CORO2B,GABBR1,CHL1,GATM,IRF8,MEF2C,MKLN1,STRN3,HYDIN,MTMR10,RIPOR1,RAD51D,RADX,ZNF532,C12orf49,RMI1,ZNF821,CPEB3,SLC2A5,PEG10,NEK4,TCF4,TRIO,EVI5,DPF3" Coexpression M4658 Genes up-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.25E-04 1.00E+00 2.97E-03 2.94E-02 40 197 "ATP6V0E2-AS1,ACTN1,KLHL32,MTA3,GPRASP2,SLC2A11,CARS,SCARB1,NOG,ARHGEF4,ARHGAP32,SLC12A6,ARMCX1,KIAA1958,ADGRA3,ZNF496,USP51,IL6ST,ZNF667-AS1,MEST,THYN1,LAYN,NRCAM,RETREG1,LRRN3,ZIK1,ZNF844,FAM184A,ZCWPW1,BEND5,GAL3ST4,RFX2,EXD2,FAM102A,CNKSR2,RNF175,DICER1-AS1,PRRT1,CDK20,MICU3" Coexpression M2945 Genes up-regulated in activated T lymphocytes: T conv versus natural T reg. MSigDB C7: Immunologic Signatures (v6.0) 1.25E-04 1.00E+00 2.97E-03 2.94E-02 36 171 "ACTN1,ADCY6,TNRC6C,SFMBT2,ARHGDIG,MAP4K4,IPCEF1,RIMS4,HDAC4,ECM2,PLEKHA1,CHST15,RAPGEF6,SESN1,PCDH17,GGT5,TDRKH,AGFG1,DISP2,IL6ST,SLC35G1,SMAD1,PIK3C2A,VPS13C,PTK2,EML5,CEP97,BEND5,AP1AR,ST6GAL1,SLC4A3,TET1,ARFGAP1,SSBP2,OSBP2,TOM1L2" Coexpression 17875932-TableS4 Mouse Leukemia_Torchia07_928genes GeneSigDB 1.28E-04 1.00E+00 3.02E-03 3.00E-02 89 543 "NDRG2,TMCC3,PITPNM2,KCNAB2,CPNE5,MARCH3,ZSCAN18,N4BP2L1,DOCK11,ARHGEF2,MAGI1,RCBTB2,MAP4K4,HOMER3,CNN3,PCYT1B,CREM,GDA,SOCS5,ZFYVE16,DOCK2,ARRDC4,KLHL5,FRY,OPTN,PLXNC1,F5,SCML2,FDFT1,NBEA,PDLIM5,TPK1,KHDRBS3,ST6GALNAC3,FYN,IQGAP2,CPLX2,GCNT2,DCLK2,ADGRA3,GP1BB,TDRKH,GRB10,GSTT2,NCKAP1L,HLF,ACOT7,CPT1C,SOWAHA,MAN2A2,MAPT,LYPLAL1,AQP11,TM6SF1,MEF2C,MEIS1,MEST,MYCN,PCBP3,PDE4B,SMOX,SCHIP1,SEPT4,BCAS3,CNTLN,CASTOR1,SH3TC2,NUDT11,ATP8B4,SATB1,ZFP2,FAM102A,PPM1E,NUBPL,NMNAT2,ITPRID2,CEP68,RGL1,TBCEL,DOCK9,ZMAT3,BEX4,RUSC1,SGK3,PDIA2,WIPF1,SLC38A1,PLSCR4,RSPRY1" Coexpression M8898 Genes down-regulated in CD4 [GeneID=920] versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.34E-04 1.00E+00 3.16E-03 3.13E-02 37 178 "MARCH3,LDHD,CD86,ABCG2,MAP4K4,LRIG1,IPCEF1,GALNT9,CDON,FSD1L,EVL,DCLK2,ADAMTS6,ATXN2L,ITPKB,SMAD1,NACA,NF1,SLC11A2,P2RX7,PDE4B,PLCB2,SH3KBP1,PPP3CC,RBBP6,RXRA,SEMA6D,GALNT10,SH3GL3,ST6GAL1,ST8SIA1,ARHGAP26,TIAM1,TTC3,VIPR2,SLC38A1,TMEM63C" Coexpression 19074870-SuppTable4a Human StemCell_Harris08_490genes GeneSigDB 1.34E-04 1.00E+00 3.16E-03 3.13E-02 69 398 "ACHE,NDRG2,ARRB1,RIPK1,BCHE,NRP2,ST3GAL5,WASF1,CAPN3,SLIT2,FBXO7,MAP4K4,ARHGEF6,CNTN1,COL9A1,COL9A3,COL11A2,MYRIP,NRG2,HAPLN1,ABCG1,CSNK1E,GPRASP1,SEMA3D,ELN,EPHB1,ERBB2,TUBB3,FGF1,FGFR3,FLT1,FYN,ADAM28,GNAO1,GP1BB,GSN,HAS2,MBP,CHST6,MMP16,MMP17,GIT1,MYO5A,NFE2L2,CLDN11,P2RX7,ENPP2,PKD1,PLCD1,FXYD1,PPP2R2B,PPP2R2C,RET,ROBO1,S100B,MAPK12,SH3GL3,ABLIM3,SLC8A1,SLC12A2,SNAP25,SNCA,SPP1,DOCK9,TNS2,TRO,UGT8,XPO1,ANKS1B" Coexpression 18977325-Figure5f Human Leukemia_Krivtsov08_36genes GeneSigDB 1.35E-04 1.00E+00 3.16E-03 3.14E-02 12 33 "ARHGEF1,CD38,ABCG1,PPP1R16B,HDAC9,SLC12A6,RASGRP1,GPSM2,OXR1,GSTCD,IFT122,SP4" Coexpression 12446012-Table3 Mouse Immune_Carmody02_40genes GeneSigDB 1.35E-04 1.00E+00 3.16E-03 3.14E-02 12 33 "HCN2,CACNA1G,CACNA1A,SLC25A14,SNAP91,CHL1,GFRA2,GUCY1B1,OPRL1,SCN8A,SNAP25,SYT1" Coexpression 19880498-TableS6 Human Leukemia_Kang09_352genes GeneSigDB 1.36E-04 1.00E+00 3.19E-03 3.16E-02 45 231 "ADCY6,PITPNM2,APBB2,LINC00173,PROM1,BMPR1B,WASF1,PRC1,CD38,RCBTB2,NRXN3,AKAP12,OSBPL3,CSNK1G3,CYBB,RASSF2,DAPK1,DBN1,E2F5,EPB41L2,ARMCX1,MPP6,RAB30,ADGRA3,GUCY1A1,IRAK3,TOX2,BACH2,TTYH2,LMO2,SMAD1,ZNF92,NPY,PCDH9,PDE4A,SCHIP1,BAALC,RCOR3,FNBP1,SAMSN1,ANKRD28,AKTIP,PARD3,LMF1,KCNK12" Coexpression M8907 Genes down-regulated in pro-B cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.39E-04 1.00E+00 3.24E-03 3.21E-02 34 159 "PWWP2A,MTUS1,APBB2,MARCH3,UBE2L6,LRIG1,IPCEF1,GALNT9,DBN1,KLHL3,DMPK,EBI3,EVL,STAU2,DCLK2,AGFG1,ZIC5,MARK1,PDCD2,PDE4B,SH3KBP1,SEMA6D,ST6GAL1,SLC14A1,SOX11,CLSTN2,VPS13A,FRYL,USP1,VIPR2,KCNT2,NAV3,TMEM63C,SENP7" Coexpression M2241 Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D Matrigel only. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.39E-04 1.00E+00 3.24E-03 3.21E-02 138 916 "C3orf14,METAP1D,BEND6,TAOK1,OGT,CDC42BPA,USP37,CDC14B,TMEFF1,ATP1B3,ALDH7A1,BARD1,FUBP1,NAE1,PTBP2,PRC1,SEPT7,CCPG1,NOG,CFL2,SOCS6,CNOT8,QKI,RCHY1,BAG4,CREM,ANKRD44,UBXN2A,RIMS2,YTHDC1,FBXL5,SACS,FARSB,GOLT1B,EEF1D,KLHL5,AASS,EIF5,COPS4,STARD3NL,DCTN4,SUCO,SEC23B,SYNCRIP,SMC2,ATP2C1,CELF1,SARAF,RAPGEF6,ZNF234,ZNF274,ERAP1,MTHFD2,ZNF559,ARFIP1,TXNL4A,COPS8,DBF4,SPIN1,CBX1,HTATSF1,FERMT2,PSIP1,KLHL23,KIF2A,KTN1,LAMP2,STMN1,MBNL1,MID1,POC1B,MYO5A,HNRNPM,NINJ2,NUCB2,OPA1,DPY19L2P2,PFKFB3,GPSM2,STRN3,PSAT1,ING3,PPM1B,PPP2R5E,PPP3CA,BDNF-AS,PTK2,MARCH1,IQSEC3,OXR1,RPE,FBXW7,MELTF-AS1,RMI1,SARS,CSRNP3,SEC14L1,TRA2B,SH3BP2,FBXO11,SNRPN,DOP1A,BDP1,UHRF1BP1L,ZBTB43,RBM26,NEK4,ZC3H4,PRRC2C,ANKRD28,ANKRD12,MTCL1,TAF9,TCEA1,TCF12,C18orf54,CBX5,TMPO,TPM1,RUNDC3B,TUBB2A,RPL7L1,UBE2H,USP1,CCDC14,XRCC4,ZIC2,ZNF23,ZNF24,TMEM237,UPF3A,KCNAB1,MRPL47,KAT6A,SMIM8,PHTF2,FRMD6,SENP7" Coexpression M8697 Top 20 genes whose up-regulation correlated with gastrointestinal stromal tumors (GIST) and synovial sarcoma compared to other tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.40E-04 1.00E+00 3.24E-03 3.21E-02 9 20 "DPP10,APLP1,BCHE,COL4A5,EDN3,ADGRA3,KIT,PLCB2,ITM2C" Coexpression M9236 Genes down-regulated in CD8 T cells with STAT4 [GeneID=6775]: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 1.40E-04 1.00E+00 3.24E-03 3.21E-02 40 198 "TNRC6C,EIF4G3,ATP6V0A1,JAZF1,ZFP28,CDC42BPB,SIPA1L1,FAM169A,PUM1,ARHGAP32,PLEKHA1,NBEA,SARAF,SYT17,SESN1,BACH2,IRF8,MEF2C,BLOC1S2,MYO9A,NFYA,ABCB1,VPS13C,PTK2,BEND5,TMLHE,PCMTD2,SATB1,CNKSR2,SLC12A2,COA1,ZHX3,KDM4C,FRYL,TMPO,ZNF711,ZNF154,SLC30A4,HPS4,NETO1" Coexpression M3343 Genes up-regulated in comparison of polysome bound (translated) mRNA before and 16 h after LPS (TLR4 agonist) stimulation. MSigDB C7: Immunologic Signatures (v6.0) 1.40E-04 1.00E+00 3.24E-03 3.21E-02 40 198 "AMPD2,ARRB1,CAMK2G,FOXN3,CNRIP1,PREPL,HDAC4,TBC1D5,ELMO1,SACS,SGSM2,BAIAP2,EVL,HVCN1,TDRKH,GSN,AGBL5,METTL21A,LIMS1,MAN2A2,TM6SF1,NCF2,FITM2,MTMR10,TTC13,ATP8B4,RXRA,TRERF1,PDLIM2,KIAA0930,USP22,ARHGAP9,ZMAT3,ZNF106,TMEM9,NACC2,LRRC8A,TSC1,TTC3,MFF" Coexpression M18120 Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [GeneID=406967;406997] at 24 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.40E-04 1.00E+00 3.24E-03 3.21E-02 135 893 "CLK4,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PKP4,APC,TMEFF1,ZFYVE28,ZBTB10,BARD1,BLM,DST,FUBP1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,RCBTB2,B4GALT6,FAM189A2,AKAP7,FAM171B,LRIG1,ARHGEF10,APPL1,CTH,DNAL1,DBT,PITPNC1,CDON,PHC2,IRAK4,PCOLCE2,EXTL2,CLVS1,CORO2B,ST3GAL6,CEP78,TMEM164,MEX3B,SEC23B,SYNCRIP,SEMA4D,SMC2,KHDRBS3,SARAF,KIAA1841,GATM,KIAA1958,KCNMB4,RAB40B,GPR37,CIT,FAM222A,RASSF8,ELOVL5,GAREM2,ZIC5,LRRCC1,IL6ST,SLC35G1,KLHL23,KPNA5,LIMS1,MAN2A2,MEIS2,MXI1,SFR1,NEK1,NFYA,NUCB2,OPA1,GPR137C,SNX10,KCTD15,GPSM2,PRIMPOL,MINDY2,EPDR1,MAPK9,VPS13C,PTPRE,RADX,TRIM68,RET,RIC8B,RNASEL,MAP6D1,RMI1,HES6,ZFP30,FERMT1,ANKRD6,WDR47,KDM4D,SLC9A5,ZFP1,LIMCH1,FAM126B,FNBP1,SP4,SS18,TBL1X,SATB2,RPGRIP1L,DICER1,SIRT1,RP9P,C18orf54,ZMAT3,TMPO,ZNF346,STXBP4,UGT8,USP1,BCL2L13,CCDC14,XPO1,ZBTB14,ZNF45,LYPD6,REEP1,ZNF184,NT5M,STOX2,EPM2A,PHTF2,FBXO36,MSRB3,NHSL1,SPATA13" Coexpression 17414055-Table3 Human pancreas_Kim07_59genes GeneSigDB 1.43E-04 1.00E+00 3.30E-03 3.27E-02 16 53 "CRLF1,SLIT2,AKAP12,BOC,RCAN2,ABCA8,FHL1,GHR,IL6ST,NLGN3,SEPT4,PCDHB7,TNS2,ZNF610,LGI4,MICU3" Coexpression M939 Genes up-regulated in hematopoietic progenitor cells (HPC) of B lymphocyte lineage CD34+CD45RA+CD10+ [GeneID=947;5788;4311]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-04 1.00E+00 3.30E-03 3.27E-02 54 293 "KDM5D,SEMA6A,CDK13,ZBTB10,BARD1,ARHGEF7,LDLRAD4,DDR1,CALM1,CAPN3,HIP1R,ABCG2,MAP4K4,ENTPD4,AKAP12,LRIG1,ZFYVE16,DBN1,E2F5,RASGRP1,KMT5B,CORO2B,CHST15,RASL10A,ADGRA3,LILRA2,BTN2A1,RNFT2,BACH2,AGFG1,SMAD1,MEF2C,NPY,PCDH9,DUSP26,RETREG1,SCHIP1,PPM1B,PPP3CC,PTPRE,TTC13,MSANTD2,SMARCA4,KIF13A,TMCC1,ZNF423,VPS13A,COBL,TCF4,SSBP2,LMF1,ZNF177,HPS4,JMJD1C" Coexpression 17234769-TableS2b Human StemCell_West07_669genes GeneSigDB 1.44E-04 1.00E+00 3.30E-03 3.27E-02 87 530 "NDRG2,C1QTNF1,SEMA6A,LTBP4,AMPD3,AMT,OGT,GAS7,APOC1,ATP1B3,IL33,RGN,CDH2,DLGAP1,RCBTB2,CREM,CRHBP,ABCG1,CSF1,VCAN,CTH,RIMS2,CYBB,GPRASP1,HDAC4,RASSF2,SPOCK2,HEPH,SV2B,SGSM2,CHRDL1,EEF1D,EGR3,SRPK3,ST3GAL6,FGF12,FHL1,GABBR1,INPP5K,ALDH1L1,CSDC2,GGT5,POLL,LUZP2,KCNJ5,KCNK3,KCNN2,LAMA2,MEIS2,ADAM22,MYO7A,NBL1,ABCB1,DUSP26,FXYD1,PLTP,SEPT4,LRRN3,MAPK10,CNNM2,PTCH1,PTH1R,ACSM5,PID1,KLHDC8A,BAALC,ZNF331,SCN7A,FERMT1,SIRT2,INTS9,TMCC1,PDZRN3,LHPP,CEP68,PCDHGC5,TEK,SIRT1,TK2,TNS1,UBTF,LMF1,VSNL1,FTSJ1,SEMA3B,FAM182B,ADAMTSL3" Coexpression 18689800-TableS5 Human EmbryonicStemCell_Thomas08_839genes GeneSigDB 1.45E-04 1.00E+00 3.32E-03 3.29E-02 121 786 "ADORA2A,AP2A2,OGT,PHF12,APBA2,APBB2,APC,APLP1,CASK,ZBTB10,NCOA1,BMP7,FUBP1,JAZF1,CCNH,CDC25B,MAP4K4,MAGED1,TBPL1,CREM,RBM39,RNF14,NCOR1,NCOR2,CSNK1E,HDAC9,MAML1,MYEF2,MED12,NR1D2,DMTF1,DNAJB6,E2F5,EEF1D,EIF4G2,ERBB2,ERCC2,ETV1,ZNF589,FGFR1,STAMBP,TRIM16,CAMKK2,ATP2C1,KHDRBS3,ZNF274,BRD8,TCERG1,RNPS1,GLI2,CBX1,GRB10,ZNF496,SOX21,IL6ST,SMAD1,MBD1,MEIS2,AFF1,MXI1,MYCN,MYO6,NFE2L2,NFYA,PAX6,PDPK1,POLR2F,PPP3CA,PPP5C,MAPK3,MAPK7,PTK2,RBBP8,RGS12,RXRA,SAFB,SALL1,SATB1,HES6,SH3BP2,EPN2,SIRT2,ATF7IP,EPC1,SMARCA4,SMARCC2,SMARCD3,SOX11,SP2,MYCBP2,PEG10,ZNF423,TROVE2,ERBIN,SUPT5H,TAF9,TBL1X,TCEA1,TCF4,SIN3B,TCF12,NSD1,CRTC1,SIRT1,TIAM1,CBX5,TMPO,PARD3,TP53BP1,TP53BP2,TSC2,HIRA,UBTF,WIPF1,ZBTB14,ZNF24,SPHK2,POLR3H,NELFE,FZD3,JMJD1C" Coexpression M1551 Genes whose splicing in neocortex was most affected by knock out of NOVA2 [GeneID=4858]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.51E-04 1.00E+00 3.44E-03 3.41E-02 14 43 "CASK,CACNA1B,CAMK2G,MAP4K4,EPB41,EPB41L2,GPHN,STX2,CHL1,IDH3B,LRP1B,LRP12,SPTAN1,CLASP1" Coexpression M8889 Genes down-regulated in multipotent progenitors (MPP) versus lymphoid primed MPP cells. MSigDB C7: Immunologic Signatures (v6.0) 1.51E-04 1.00E+00 3.44E-03 3.41E-02 37 179 "ADCY8,ALCAM,FAM135A,DST,HIP1R,DGKI,CREM,AKAP12,PPP1R16B,CENPL,FAM107B,DNAJB6,STX2,DENND4A,ST6GALNAC3,MALT1,TOX2,PADI2,ACOT7,ICA1,IDH3A,MYO6,PCSK1,PRKAB2,GRAMD1C,PTPN13,SEMA6D,SCP2,SLA,MAPKBP1,TEX2,SAMSN1,NXT2,SEPT8,TTBK2,EVI5,PLSCR4" Coexpression 20211691-TableS1 Mouse NeuronalCells_Provenzano10_158cells GeneSigDB 1.51E-04 1.00E+00 3.44E-03 3.41E-02 24 98 "ADCY8,ARRB1,RASL11B,CALB1,DCLK1,SEC24C,DBN1,DMD,DMPK,SCML2,FRMD3,IGF1,SYTL4,GPR155,NELL2,NTRK3,DUSP26,GDPD2,PTPRD,SUSD4,SEMA6D,FRMPD1,SLC14A1,DOCK9" Coexpression 16488994-SuppTable1b Mouse Lung_Lu06_856genes_Array MEO430Av2 GeneSigDB 1.53E-04 1.00E+00 3.46E-03 3.43E-02 75 443 "ADCY8,ADORA1,ADRB2,ALCAM,LTBP4,PKP4,ARRB1,NUMB,MPDZ,PROM1,LRBA,RAB28,PLAA,HOMER3,CNTN1,COL4A5,AKAP12,CSF1,CSNK1E,VCAN,EDN1,EGFR,RASGRP2,F5,FECH,FER,FGFR1,FHL1,FLT1,FYN,SESN1,GGT5,LYVE1,CRCP,FERMT2,LNX1,GP1BB,STMN2,GUCY1B1,HP,IGF1,IL6ST,ITGA7,ITPKB,KCNH2,KIT,LAMA2,MBP,MITF,MYO6,MYO7A,NBL1,P2RY1,PALM,PCSK5,GNG2,PMP22,RELN,PTPRB,PTPRD,PTPRE,ROGDI,RASGRF2,DPF2,RGS4,ROBO1,RPS6KA2,MRAS,SPP1,TNS2,PCDHA1,TEK,ZMAT3,ZNF106,BEX4" Coexpression 15955831-Table6 Human StemCell_Komor05_80genes GeneSigDB 1.53E-04 1.00E+00 3.46E-03 3.43E-02 20 75 "ADCY6,PPFIA3,RGS9,CDC42BPB,RGS6,PDE4DIP,DGKG,PDLIM5,FERMT2,GP1BB,IGF1,ITPKB,MSR1,TREM2,LRP12,MEG3,SIN3B,ZFPM2,PARD3,HRASLS" Coexpression 15475448-Table3 Human Thryoid_Chevillard04_139genes GeneSigDB 1.53E-04 1.00E+00 3.46E-03 3.43E-02 26 110 "ADD1,APLP1,ATP2B2,SCARB1,QKI,CNN3,CSF1,DPP6,PDCD6IP,EPHB1,SRRM1,ERCC2,FGFR1,OGA,GNAL,KCNF1,MAP4,NTRK2,NTRK3,PDCD2,POLG,PTPRE,SLC12A4,PEG10,UBE3A,VSNL1" Coexpression M2424 Genes up-regulated in neonatal cardiac myocytes upon knockdown of BCL3 [GeneID=602] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.54E-04 1.00E+00 3.47E-03 3.44E-02 64 364 "ACADM,AXIN2,ADRA1D,OSBPL6,LDHD,CA4,CH25H,PRC1,CDO1,UBE2L6,CNR1,AKAP12,DGKG,MYEF2,EDIL3,EDN1,EDNRB,RASGRP1,SEMA3D,AASS,CALCRL,NCALD,ABCA8,SDCBP2,ACSS1,GATM,PPARGC1A,LOXL3,LNX1,GPD1,UBE2QL1,ACOT7,HP,IGF1,IL6R,KHK,MATN2,MOV10,MYH3,TCEAL5,FXYD7,NEFM,CLDN11,PCSK5,PFKFB2,PFKFB4,PGAM2,SERPINI1,SEPT4,MASP1,VPS13C,PTN,FIGN,RORB,HUNK,SYBU,LIMCH1,SSTR2,BEX4,RASD2,SGK3,VLDLR,ZNF23,TMEM178A" Coexpression M5413 Genes up-regulated in comparison of eosinophils versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "ALCAM,FAM131A,CADPS,MARCH3,CAMK2B,LRRFIP1,RAB33A,SH2B1,CYBB,DOCK4,ACOT8,ANKRD46,CNNM1,PLXNC1,FCGR1A,FGFR1,CELF1,GAA,GALC,TMEM8B,NEU3,GLUL,INPP5B,CDH20,MBP,MYO5A,P2RY13,KLK6,FAM184A,RBBP8,HUNK,STUM,ARHGEF40,SLC11A1,ATP10B,ARC,MCF2L,SYNE1,ZFPM2,UGT8" Coexpression M8874 Genes down-regulated in common lymphoid progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "CDC42BPA,EP400,CCAR2,BCHE,CA12,KALRN,DPYSL2,TPK1,TPPP3,GNAL,GUCY1B1,PADI2,BACH2,L1CAM,MBP,SHC3,MEIS2,NBL1,PDE1B,SDK2,PPP1R1A,LRRN3,STK32B,SLC2A5,LIMS2,MYO16,CEP68,PHLDB1,AGTPBP1,ZEB1,PCDHGA9,DOCK9,TP53BP2,SSBP2,FAM155A,CLIP2,DNALI1,HPS4,UBE3B,FXR1" Coexpression M9933 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 6h. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "KCNH8,ACHE,SRPX,ANK2,STK33,HIP1R,ARHGAP33,NOG,MYL6B,CNR1,FAM149A,COL11A2,SLC35F1,EDNRA,TMTC1,ATP13A4,PSD2,HHIPL1,ABLIM2,GABRB3,SYT17,GGT7,GNAO1,INSM1,C2CD4C,KCNJ16,SMAD9,NEFM,NEFH,TMOD2,TMEM255A,CARF,MAP6D1,KIF21A,ZNF334,ARC,PCDHB7,RIMBP2,HIRA,CLEC2L" Coexpression M5564 Genes up-regulated in comparison of basophils versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "CCAR2,NPIPA1,DCAF8,FBXL5,UBE2E3,SARAF,GALC,IQGAP2,BRD8,MSL3,GRIA2,BACH2,HP,KIF5A,KIT,MBP,MEIS2,NACA,P2RY13,PCSK5,PMP22,PRKACB,PRKCB,ZCWPW1,PCMTD2,SCP2,R3HDM2,SLC4A3,ARHGEF40,BTBD7,LMBRD1,TSNAXIP1,POGZ,AGTPBP1,ZNF106,TLR4,BEX4,WIPF1,ZNF32,PRDM8" Coexpression M8609 Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437]. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "NDRG2,PITPNM2,APBA2,ATP1A1,CCNH,NOG,LETMD1,IPCEF1,GPRASP1,ARHGAP32,ZNF337,WDPCP,RASGRP2,SARAF,GGT7,ZNF638,LINC01089,BACH2,HSF2,ITPKB,KPNA5,MBNL1,BEX5,PLCL1,PTK2,ZCWPW1,GAL3ST4,RPS20,ZNF331,CNKSR2,CCDC88A,IFT122,SNRPN,ADAMTS17,SIN3B,ERCC6L2,TPM2,TOM1L2,WNT7A,ZNF540" Coexpression M5208 Genes down-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "ADRB2,PKP4,SCAPER,SGCE,MYRF,CCK,CCNT1,B4GALT6,COL4A5,CRYM,AATK,FAM131B,TCAF1,TMCC2,RASGRP2,RRAGB,OLFM1,SEC23B,FLNC,GABRB3,B4GALNT1,ERAP1,LPAR4,HP,INPP5B,ITPKB,MATN2,NOVA2,C19orf57,POU6F1,PEX2,RPE,RYR3,PPM1E,INTS9,KDM4B,SOX15,ERC1,MTCL1,USP22" Coexpression M6371 Genes up-regulated in bone marrow-derived mast cells: wildtype versus ADCYAP1R1 [GeneID=117] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.57E-04 1.00E+00 3.50E-03 3.47E-02 40 199 "NDRG2,OSBPL6,SLC4A4,KIF1A,VXN,CBLN1,CD86,NUMBL,FOXN3,CNN3,C2CD2,CRMP1,SEC14L5,AIF1L,ELN,DENND4A,FGF12,CPLX2,GCNT2,GPR162,MAP7D2,CCDC184,LRRC75A,GAREM2,KCNF1,MGAT3,MMP17,PDZRN4,FA2H,IRX1,SEMA6D,ANKRD6,ZNF334,ST5,CEP68,RGL1,STX1A,SYN2,TRIM9,KCNAB1" Coexpression 18794137-SuppTable1e Human Breast_Creighton08_643genes GeneSigDB 1.58E-04 1.00E+00 3.51E-03 3.48E-02 77 458 "MTA3,MTUS1,ALCAM,BCAS1,SFMBT2,NCOA1,RASL11B,DOCK11,BMP7,SYNJ2,HIP1R,RUNX1T1,CFL2,COPB2,SOCS6,CLTC,QKI,RUBCN,DBI,MFAP3L,SGSM2,CPEB2,ABCC5,PHF20L1,GOLGA7,VPS13B,EPB41L2,ERBB2,ERBB4,FAM198B,FGF12,FGF13,MALT1,LNX1,GRB10,DIDO1,GSN,ZHX1,ICA1,INPP1,LSS,MATN3,MBNL1,COL28A1,NCAM2,NF1,PCBP3,SLC11A2,NUCB2,ZNF827,PMP22,STRN3,EPB41L4B,PTPN13,RIPOR1,ZDHHC4,SGSM1,GALNT10,WDR37,SLC12A2,LIMCH1,PDZD2,FNBP1,NXT2,KLHL7,TACC1,TCF4,AKTIP,NACC2,BEX4,RPRM,GORASP1,TBC1D15,RICTOR,REEP1,SPIRE1,RNF103" Coexpression M16407 Genes in the expression cluster 'LT-HSC Shared': up-regulated in long term hematopoietic stem cells (LT-HSC) from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.58E-04 1.00E+00 3.51E-03 3.48E-02 55 301 "KIAA1324,SPARCL1,MYOM1,MPDZ,SCAPER,LDB2,C1orf52,LARGE1,FOXN3,RAB33A,CNTN1,ARHGEF10,PDE4DIP,INTS1,DNM1,EGR3,PLEKHA1,EPB41L2,SLC43A2,NSRP1,SLC9B2,SYT3,NBEA,GAA,FUT10,PCLO,HLF,SYNPO,KNDC1,MAPT,MARK1,MATN2,CHIC1,ADAM22,PCDH9,BEND5,DUSP15,DCUN1D2,STX1B,CCDC112,SLC12A2,LGI3,ZFP1,IFT122,SPATA7,SYN2,DOCK9,TNS1,RPRM,EIF4ENIF1,CLEC2L,ANKS1B,PLSCR4,DOCK8,AAAS" Coexpression 19192944-TableS4 Human Ovarian_Crijns09_2394Genes_17PathwayPredictor GeneSigDB 1.60E-04 1.00E+00 3.54E-03 3.51E-02 222 1584 "ACTN1,ADCY5,ADCY6,ADCY8,AXIN2,ADORA2A,UNC5A,ADRA1D,ADRA1B,ADRB2,NME5,SEMA6A,ALCAM,AMH,AMPD2,AMPD3,SEMA7A,MAP4K3,APC,CDC14B,SEMA4G,CASK,ARRB1,ARRB2,PDE8B,ATP2A2,ATP2B2,ATP6V0A1,MPDZ,BID,BMP7,BMPR1B,ARHGEF7,CACNA1I,CACNA1G,WASF1,CACNA1A,CACNA1B,CACNA2D1,CAMK2A,CAMK2B,CAMK2G,CLDN10,CCNH,CD86,ARHGEF1,CD38,ENTPD2,ENTPD6,CDC25B,CDH2,MAGI1,CACNA2D2,CFL2,SOCS6,TAOK2,SLIT2,NRXN3,NGEF,MAP4K4,ARHGEF6,CNTFR,CNTN1,COX4I1,NECTIN3,ENTPD4,GDA,CSF1R,CSNK1E,SOCS5,CNTNAP2,ARHGEF4,CYBB,TIAM2,PARD6A,DPYSL2,DUSP9,E2F5,EDNRA,EDNRB,RASGRP1,SEMA3D,EGFR,PLXNC1,EPB41,EPB41L2,RASGRP2,ERBB2,ERBB4,APC2,PTK2B,FGF1,POLR1B,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,BAIAP2,MAD2L2,ATP5PD,SEMA4D,FLNC,ATP6V1H,ABLIM2,FYN,IQGAP2,GCK,GHR,PPARGC1A,DBF4,GNAL,PLCD4,GRIN2C,GRIN2D,GSN,GUCY1A1,GUCY1B1,NCKAP1L,NEGR1,MYLK2,IGF1,NKD1,TJAP1,IL6R,IL6ST,IL12A,ITGA7,ITGAM,ITPKA,ITPKB,JAK2,KIT,L1CAM,LAMA2,STMN1,LIFR,MAPT,MATK,SHC3,MEF2C,KITLG,AFDN,GIT1,NCAM2,NCF2,NF1,NME4,NPR2,NRCAM,NTRK2,CLDN11,OXTR,P2RX7,PDE1C,PDE3A,PDE4A,PDE4D,PDE1B,ENPP2,PDPK1,SEMA5B,PIK3R1,PKM,PLCB2,PLCD1,PLXNB1,POLR2F,PPM1B,PPP2R2B,PPP2R2C,PPP3CA,PPP3CC,PPP5C,PRKAB2,PRKACB,PRKAR1B,MAPK3,MAPK7,MAPK9,MAPK10,PRPH,RELN,NDUFS7,LAMA1,PTK2,RASGRF1,RASGRF2,RDX,RGS3,ROBO1,RPS6KA2,RYR3,MAPK12,SEMA6D,TNFRSF19,MRAS,SH3BP2,NLGN1,ABLIM3,CXXC4,SPP1,UNC5B,SPTAN1,TACR1,FBXW11,TBL1X,TIAM1,PARD3,PIK3R5,TSC1,TSC2,VAV1,WNT7A,SPHK2,DPYSL5,MAP3K12,NT5M,SEMA3B,FZD3,SOCS4" Coexpression 19808871-TableS3 Human StemCell_Hassan09_1544genes GeneSigDB 1.68E-04 1.00E+00 3.67E-03 3.64E-02 157 1068 "ACADM,ACHE,ADCY8,ADD2,KIAA1324,SEMA6A,AMPD2,AMPD3,PARG,APC,CDC14B,CDK10,TMEFF1,RGS20,CHRD,ADAM23,BLM,BMP7,NAE1,CACNA1G,CA4,CACNA1B,CACNA2D1,CAMK2G,CH25H,SPAG9,PRC1,CBLN1,CBS,SYNGR3,DGKI,AP4M1,CDC25B,LARGE1,CRLF1,SLIT2,LHX2,VAX2,CNTFR,IQCK,COL4A5,TBPL1,NRG2,CRMP1,LRIG1,PDE4DIP,CNTNAP2,RIMS2,DGKG,DBI,DCTN1,SV2B,DPYSL2,DTNA,DNAJB6,CNNM1,EGR3,EPHB1,ERBB2,ERBB4,ETV1,PIPOX,OLFM1,FGF13,FGFR1,HPCAL4,DCTN2,OGA,GABRB3,GAD1,MTHFD2,PCDH17,GHR,MSL3,POLL,ADGRA3,GPR12,LPAR4,STMN2,GRIA2,CIT,PTPRT,PSIP1,GUCY1A1,HAS2,HBA1,IFI16,ITPKA,KCNN2,KCNQ3,STMN1,LIG4,MAN2A2,MAPT,MAT2A,SCAMP5,NEK1,NFIX,NPTX1,NTRK2,PAX6,PCDH8,PDCD2,ENPP2,TMOD2,PLEC,PMP22,PPM1B,PPP3CA,PPP5C,MAPK4,QDPR,RAD17,RASGRF1,RBBP8,CRTAC1,REV3L,ROBO1,RYR3,SALL1,PKNOX2,SLC6A8,SIRT2,SMARCA4,SOX11,LHPP,CLASP2,TROVE2,SSTR1,SSTR2,SUPT5H,ASTN2,TAL1,TCF12,CLASP1,SIRT1,CHST8,HEY1,TK2,CBX5,ICAM5,TMPO,TPM2,TSC2,FLRT2,VSNL1,WNT7A,KCNK12,ZIC1,TRIM9,ZNF195,TFIP11,SLC30A3,SLC30A4,NT5M,KCNAB1,FXR1" Coexpression M2673 Genes down-regulated in HUVEC cells (endothelium) by treatment with PIGF [Gene ID=5281]. MSigDB C6: Oncogenic Signatures (v6.0) 1.68E-04 1.00E+00 3.67E-03 3.64E-02 39 193 "PPFIA4,KCNAB2,APOC1,ATP1A3,ATP2B2,CFAP410,CAMK2B,ENTPD2,LOC730101,DLGAP1,TAOK2,IQCK,COL11A2,SNX29,MTSS1L,SRCAP,GFRA2,GNAL,GRM2,CLASRP,KCNQ3,MSI1,NELL2,NPR2,PDE1B,ENPP2,PKD1,PTPRH,KHDRBS2,MAST1,SPTB,NFASC,SSTR2,ARC,MCF2L,SMG6,TRIO,UBE2H,VGF" Coexpression 20436685-ST6-2 Human Breast_Pothuri10_180genes GeneSigDB 1.69E-04 1.00E+00 3.67E-03 3.64E-02 35 167 "AK2,OGT,MARCH3,ADAM23,ZMYM4,CRYBB1,SOCS5,SLITRK5,TCAF1,RASGRP1,FRY,FAM13A,VPS13B,NCALD,FUT9,GAD1,GPR37,IRF8,MARK1,MEF2C,PLCL1,PRKACB,RAD17,SLC25A36,BAALC,CASC3,FNDC3A,ST8SIA1,SOX3,UHRF1BP1L,RBM26,SEPT8,KLHL4,DNAH7,VIPR2" Coexpression M6122 "Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 20 h time point that were not up-regulated at the previous time point, 18 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.72E-04 1.00E+00 3.67E-03 3.64E-02 46 240 "GAS7,ATP1A3,HCN2,USP6,CLGN,CBARP,AHCTF1,CLOCK,ERC2,USP6NL,ARHGAP32,E2F6,ZNF391,KHDRBS3,CELF1,TOX3,STARD3,GPR37,GUCY1B1,ATXN2L,INPP1,KCNH2,MAPT,MPP2,NTRK2,PCDH9,PDE4A,ABCB1,PLCL1,SEPT4,PPARA,SNRK,PTPRB,PTPRD,PTPRE,RET,SLC6A8,SEPHS1,ZBTB43,TTBK2,AGTPBP1,TIAM1,TMPO,CDK20,UBE2H,UBE3A" Coexpression M3877 Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ADD1,BRAP,AP2A1,ARHGDIA,MARK4,BACH1,LRBA,CDH2,TMEM184B,MAP4K4,NCOR1,DGKG,B3GAT3,C2CD2L,DNM1,GOLGA7,MRVI1,F5,FCGR3A,FHL1,ALDH1L1,MAP6,GIT1,PDE1B,TMOD2,RETREG2,RTN1,PUF60,AMBRA1,ARHGEF40,RCOR3,SOX11,FBXW11,KIAA0930,TPCN2,FRYL,HEY1,PCDH20,SPHK2,NT5M" Coexpression M5473 Genes down-regulated in comparison of dendritic cells (DC) versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "BRAP,SPOP,BEGAIN,BTK,CHN1,CNOT8,ARHGEF6,MYRIP,OSBPL3,ERC2,GIT2,PITPNC1,MAMLD1,EIF1,TMEM164,MALT1,BRD8,DIDO1,BACH2,HSPA1L,KIF5A,MEIS2,THYN1,NUCB2,PDE4D,NLGN3,DPF2,UBR7,SLC25A36,SUPT20H,FRMPD1,R3HDM2,SMARCC2,GLT8D1,TAL1,WSCD1,ZEB1,SYNE1,LAT2,ZNF142" Coexpression M7469 Genes down-regulated in CD4 [GeneID=920] T cells treated with IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "NDRG2,SEMA7A,CDK10,MYOM1,BACH1,SGCE,RUNX1T1,SIPA1L1,PITPNC1,ELMSAN1,FRY,YAF2,ENO2,HSPA12B,SLC9B2,MED12L,FGF11,FHL1,NBEA,GALC,GHR,IRAK3,ICA1,ADAM22,MYCN,OCRL,RASGEF1B,PKIA,WBP1L,MEG3,ZFP2,PEX26,GKAP1,PLCB1,FRYL,TEK,SMUG1,TSC1,MICU3,PLSCR4" Coexpression M9685 Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 60h. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ADCY6,C1QTNF1,MAP4K3,ARNTL,NUMB,CA12,P2RX6,CLGN,C2CD2,CSF1,GSDME,FAM107B,RCAN1,DNAJB6,PIPOX,AMOTL2,SPECC1,NSG1,SARAF,ACSS1,GLUL,STMN2,IPO5,LIFR,NF1,SCHIP1,PRKACB,PTPRE,MRPS18A,CASC3,CCDC88A,SSPO,NEK4,SYP,SYT1,WRN,ZBTB14,NDRG4,RNF103,FRMD6" Coexpression M3012 Genes up-regulated in comparison of naive versus effector CD8 T cells at the peak expansion phase (day8 after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "CLK4,ADCY6,AMPD3,MAP4K3,CASK,ARRB1,CFLAR,CNN3,ABCG1,ABCC5,PLEKHA1,RPS6KC1,RACK1,EVL,SRCAP,SESN1,GSN,IL6R,IL6ST,SMAD1,MAT2A,PTOV1,CNOT4,SLC11A2,PKD1,RETREG1,EML5,CLIP1,SATB1,FAM102A,ST6GAL1,DHX30,ZKSCAN3,MYCBP2,STX1A,TCF4,SLC44A1,SSBP2,TTC3,EVI5" Coexpression M3257 Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 3 h with YF17D vaccine. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ACADM,SPOP,CDK13,CAST,LRBA,RCBTB2,ARHGEF6,AKAP7,SEC31B,MATR3,FBXL5,SGSM2,CASP8AP2,ACOT8,ABCC5,SNX29,NELFCD,MAN2A2,PCSK5,RETREG2,PPP2R5E,CYBC1,SLC25A36,RXRA,AP1AR,SMARCC2,TEX2,ERBIN,CEP68,TTBK2,SIN3B,TCF12,DOCK9,ZNF106,CABIN1,METTL3,ZNF177,TUBA1A,PDSS2,UBE3B" Coexpression M3161 Genes up-regulated in comparison of Th1 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ADCY8,ADD2,MTUS1,RGS9,BMP7,DCLK1,CRLF1,CCDC151,SLC35F1,MYEF2,CD99L2,DTNB,DUSP9,EEF1D,RASL12,FGFR3,MAD2L2,B4GALNT1,ATOH8,AGFG1,LIFR,CNTN3,PFKFB3,CNNM2,NWD1,RGS3,RPE,ZNF354C,SH3BP2,SLC4A3,RADIL,INAVA,SST,TTBK2,FAM208A,PARD3,LRRC24,UBE3A,AGMO,NHSL1" Coexpression M5085 Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "KLHL32,TMEM108,RGS11,LRBA,MAP4K4,PUM1,ARMCX2,FAM107B,NR1D2,C8orf37,CALCRL,RCAN2,CD320,ARMCX1,ST3GAL6,PRMT5,FGF11,MEX3B,FOXO3,HVCN1,IQGAP2,PADI2,MIER3,KCNH2,SYTL4,MYO7A,NME4,TMEM38A,POU6F1,MTMR10,MSANTD2,RFX3,ATP8B4,STK32B,DGLUCY,TRIM67,SYPL1,DNMBP,SYNE1,RSPRY1" Coexpression M6839 Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naïve versus day 28 after immunization. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ACADM,OGT,ATP1A1,MTMR3,MTMR7,ARHGAP33,CSF1R,SOCS5,DOCK4,RCAN1,ENO2,EPB41L2,RRAGB,SEC23B,TMEM8B,GRB10,KAT7,RBPJ,MITF,TAGLN3,NOVA1,PIK3C2A,PLCL1,POLG,TCP11L1,RYR3,SATB1,SNCA,GLT8D1,TROVE2,CAMTA2,TTBK2,PHLDB1,SUPT5H,PLCB1,CBX5,TTTY15,CLIP2,CLDND1,EPM2A" Coexpression M3014 Genes up-regulated in comparison of naive versus memory CD8 T cells (day 40+ after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ACADM,ACTN1,ADCY6,ADD1,AMPD3,SFMBT2,ARRB1,SEC11C,LRWD1,ARMCX2,USP3,ABCC5,PLEKHA1,RACK1,EVL,SARAF,SRCAP,SESN1,GGT5,GSN,GSTT2,ELOVL5,IL6R,IL6ST,ITPKB,SMAD1,PTOV1,SERPINI1,RETREG1,QRICH1,EML5,RPS6KA2,SATB1,FAM102A,ST6GAL1,TBCEL,METTL3,SSBP2,TTC3,SLC30A4" Coexpression M6314 Genes up-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "AXIN2,APC,LGR5,CA8,CAPN3,CDO1,RBM39,VCAN,CST3,DBN1,ENO2,AGAP3,EVL,ATP2C1,SRCAP,GGT5,TNRC6A,KCND2,MBNL1,COMMD5,OPRL1,CNTN3,FAM216A,RASGRF2,SCP2,HES6,SCAF8,SH3BP2,ARX,ST8SIA1,RBM26,KLHL7,BEX4,C9orf85,METTL3,VLDLR,LAT2,REEP1,MAP3K12,RTN4" Coexpression M10026 Genes up-regulated in NK cells: control versus acute primary viral infection. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "TNRC6C,RUNX1T1,SNCAIP,TCAF1,SPOCK2,PABPC5,MRNIP,LRRC17,SYT17,SESN1,LOXL3,GRIK5,ADAMTS6,GUCY1B1,VSIG4,CPT1C,MAP6,LYPLAL1,CHIC1,MITF,MYO7A,ZNF862,NOVA1,NPR2,OXTR,SLC25A23,LAMA1,CNTLN,RASGRF2,C12orf49,ZFP30,SIRT2,INTS9,ZHX3,PBLD,MMS19,TNS2,CYB561A3,LGI4,PROCA1" Coexpression M3735 Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ADRB2,EPB41L5,APOC2,ARRB1,CCAR2,GPR146,MTMR3,SLC16A4,LARGE1,ABCG2,SMARCAL1,RBM39,IP6K1,PLEKHA1,POLK,GALC,GRIK5,SYNPO,HMGCL,IL6R,ITPKA,KHK,STMN1,ADAM11,MX1,IDNK,NEK1,OPA1,PRODH,KHDRBS2,RNH1,RPE,DGLUCY,SARS,MAST1,SEPT8,DNAJC9,P2RY12,TUBA1A,AAAS" Coexpression M9198 Genes up-regulated in T reg: induced versus total. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "AS3MT,TMCC3,GPRASP2,ALDH7A1,BACH1,ZMYM4,ARHGEF6,CSNK1E,GREB1,GPRASP1,DAPK1,ARMCX2,PIPOX,ARMCX1,PRMT5,IQCG,CHL1,GALC,SPIN1,KCNMB4,GPD2,TOX2,ACOT7,ADAM11,TM6SF1,AFDN,PTOV1,MAPK7,GTDC1,ZNF821,SH3BP2,NSFL1C,SLC37A2,USP22,TIAM1,BHLHB9,TP53BP1,TRIO,RPL7L1,ZNF32" Coexpression M9255 Genes up-regulated in dendritic cells: hydrogen peroxide [PubChem=784] versus diphenyleneiodonium (DPI) [PubChem=2733504]. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "AMPD3,MAP4K3,TMEM108,GPR146,CFLAR,MTMR2,CFL2,RCBTB2,CNN3,COL11A2,VCAN,GAPVD1,MAML1,NR1D2,EEF1D,CALCRL,ACSS1,SESN1,ZBTB49,PADI2,IL6ST,FAM69A,PPM1B,PPP3CA,PSD,PTK2,ZNF354C,SATB1,GALNT10,SGK1,FAM102A,DZIP1,TET1,ZFP1,PIK3R5,TP53BP2,RUNDC3B,AMZ1,PPP1R3F,KLHDC1" Coexpression M3385 Genes up-regulated in comparison of Th17 cells versus induced regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "MTA3,OSBPL8,APC,RCBTB2,RAB33A,ABCG2,NCOR1,UBXN2A,RASSF2,SACS,SLC43A2,VPS26C,MEX3B,VTI1B,FOXO3,JKAMP,B4GALNT1,INPP5K,GPR37,GUCY1A1,INPP1,FXYD7,OLA1,PKM,LRP12,ING3,PPP2R5E,CCDC82,ZNF354C,SUPT20H,CCDC92,FAM126B,MYCBP2,TTBK2,TACC1,TCF12,SIK3,STXBP4,RICTOR,AMN1" Coexpression M3850 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "TMEFF1,ARHGDIA,MARK4,LRBA,PPT2,TPP1,MAP4K4,CNR1,COL9A3,BAG4,NCOR1,MYADM,MAML1,DPYSL2,PHC2,EIF4G1,FGFR3,GALC,INPP5K,GLUL,GPT2,FRMD5,MBD1,AFF1,GIT1,NPTX1,GPR85,TMOD2,ZNF426,DPF2,RPS6KA2,ATXN2,MYO18A,PEX26,FAM214B,RHBDL3,KIAA0930,ZEB1,MKRN3,NLRP3" Coexpression M8294 Genes up-regulated in lupus susceptibility locus Sle2c1 B lymphocytes from: peritoneal cavity versus spleen. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "BIN1,AMT,PLA2G4C,CADPS,RHBDL1,CDC25B,DLGAP1,ASIC3,PPT2,SEC31B,SNAP91,DMPK,DOCK2,OPTN,TENM1,TNK2,MRNIP,RASGRP2,TAOK3,FCGRT,TRAF3IP2,USP19,STARD3,CIT,KAT7,PADI2,C2orf72,AFDN,MMP16,MYO6,PCBP3,OCRL,PLCD1,SGK1,CPEB3,MCF2L,THRA,ZKSCAN5,VSNL1,GDPD5" Coexpression M8040 Genes down-regulated in CD8 T cells activated by anti-CD3 and anti-CD28 versus those stimulated by IFNA2 [GeneID=3440]. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "RALGAPA1,NDRG3,N4BP2L1,ADAM23,CBFA2T2,LRBA,CCPG1,PLEKHB1,NDST3,RAB33A,BAG4,IPCEF1,DZIP3,RUBCN,GPRASP1,GAPVD1,RIPOR2,ZFYVE16,PITPNC1,ARMCX2,FBXL5,OPTN,DENND4A,TAOK3,PDLIM5,ZNF274,BTN2A1,IL6R,FAM69A,NELL2,CNOT4,OGG1,ENPP2,ABCB1,CLIP1,TTC17,MTMR14,TPM2,ZNF189,SENP7" Coexpression M9133 Genes down-regulated in T reg: GATA1 [GeneID=2623] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ABHD6,MAP4K3,NCOA1,STX16,DOCK11,SCAPER,ZMYM4,AKAP12,GPSM1,TBC1D5,MED12,PHC2,PLXNC1,IRAK4,TLR7,ANKFY1,MALT1,KDM2B,ATE1,BACH2,IL6R,FAM69A,MEF2C,NCF2,PFKFB4,SNX10,RETREG1,PLEC,CYBC1,ZNF493,BEND5,EPC1,SP4,SPTAN1,PRRC2C,FAM208A,KIAA1107,ZEB1,SYNE1,ZSCAN26" Coexpression M4579 Genes up-regulated in comparison of adult DN2 thymocytes versus fetal DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ADCY6,OSBPL1A,ALCAM,NCOA1,RASL11B,SYNJ2,BAIAP3,PITPNC1,CD99L2,CALCRL,PIPOX,FGF13,SARAF,TRAF3IP2,INPP5K,PARD3B,GSTM5,SOWAHA,IL6ST,SYTL4,MEF2C,MXI1,NEFH,PCBP3,SERPINI1,GPSM2,SMOX,EPB41L4B,RPS6KA2,DGLUCY,ST6GAL1,SLC14A1,ABTB1,SSTR2,ARC,SLC37A2,SYNE1,UCHL1,SLC30A4,FRMD6" Coexpression M3531 Genes up-regulated in comparison of activated CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "FAM135A,GPRASP2,CDC14B,DPY19L3,SCAPER,CCNH,AP4M1,ASIC3,AKAP7,BAG4,LRIG1,CTH,ARHGEF4,YAF2,KCTD3,ARMCX1,CINP,FAM49B,ARFIP1,RBPJ,SLC35G1,GATD1,KIF2A,NCOA7,NNAT,ENPP2,MAPK9,CEP97,ERI2,NUBPL,BTBD7,ELOVL4,DIP2A,BHLHB9,C9orf85,RPL7L1,GORASP1,RNF103,KLHDC1,SENP7" Coexpression M3217 Genes up-regulated in comparison of CD4 [GeneID=920] T cells activated with lamina propria dendritic cells versus regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "RNF150,BCAS1,CCPG1,KIAA0040,FAM107B,HIPK3,FKTN,DOT1L,OGA,SESN1,SPIN1,TNRC6A,ZHX1,BACH2,ZDHHC15,SCIN,LIG4,AFF1,NFIX,PCSK1,ZNF655,PLCL1,PPM1B,BCAS3,ZNF493,REV3L,ERI2,ATXN7,LMBRD1,SP2,ERBIN,STX1A,ANKRD12,ALG1,NSD1,ITGB3BP,SLC44A1,BCL2L13,ITM2C,DOCK8" Coexpression M9411 Genes down-regulated in NK cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ACTN1,MTMR3,MYRF,AKAP12,LRIG1,CSNK1E,SNPH,ZFYVE16,EIF1,ST3GAL6,CHST15,FOXO3,IQGAP2,STARD3,LILRA2,GUCY1A1,LIG4,LMO2,SMAD1,MEF2C,AFF1,MXI1,NFYA,PDE4B,SERPINI1,RETREG1,SCHIP1,PPP3CC,PTPRE,SATB1,SLC2A5,FAM214B,TMCC1,CEP68,TTBK2,RGL1,COBL,DMXL2,ZNF32,RNF103" Coexpression M5508 Genes up-regulated in comparison of macrophages versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "AMPD3,NUMB,ATP2B2,CBR1,ARHGAP22,ABCG2,BAG4,CSF1,APPL1,USP6NL,ZNF804A,PLXNC1,KCTD3,PCOLCE2,EPB41L2,ZNF589,FER,ATP6V1H,GATM,GPER1,GSN,ACOT7,RBPJ,MKLN1,MYO5A,ENPP2,SMOX,PMP22,PTK2,MARCH1,RXRA,STUM,SLC2A5,ARHGEF40,ITPRID2,STXBP1,NACC2,BEX4,TNS1,UCHL1" Coexpression M7491 Genes up-regulated in SELL dim [GeneID=6402] NK cells: NCAM1+ [GeneID=4684] versus NCAM1- [GeneID=4684]. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-04 1.00E+00 3.67E-03 3.64E-02 40 200 "ABHD6,AS3MT,ZNF608,PRX,MYOM1,RAB29,CAMK2G,CERS5,ABCG1,CSNK1E,APPL1,HDAC9,GPRASP1,RIPOR2,RASSF2,DOCK2,CALCRL,RASGRP2,EXTL2,ALDH1L1,GHR,SMAD1,MEIS1,NCF2,OCRL,CDK18,PKM,RASGEF1B,C1orf54,PEAR1,CEP68,TLR4,NPL,TRPS1,VAV1,ZNF184,PARP11,AMN1,IFT88,SPATA13" Coexpression 15150091-Table2 Human Leukemia_Schaefer04_54genes GeneSigDB 1.83E-04 1.00E+00 3.81E-03 3.78E-02 16 54 "ADRB2,KCNAB2,ATP1B3,CAPN3,LRRFIP1,RAB33A,CREM,CTH,ZFYVE16,FGFR1,PRUNE2,ITPKB,MBP,MITF,SH3BGR,TACC1" Coexpression 20460173-ImmPortCD40LvsControl Human Immune_Kong10_855genes_ImmPort_CD40LvsControl GeneSigDB 1.87E-04 1.00E+00 3.89E-03 3.85E-02 87 534 "MTUS1,APBB2,CDK13,CHRD,ATP1A3,ATP6V0A1,BCL7A,CFLAR,BMP7,DST,BTK,RAB29,DDR1,CACNB4,CALM1,CARS,RUNX1T1,SCARB1,CD38,UBE2L6,LY86,ARHGEF6,CNR1,SH2B1,LRIG1,SLITRK5,KIAA0040,HDAC9,SCRN1,GIT2,RHOBTB1,DPYSL2,E2F5,RCAN2,NCALD,SPEG,PTK2B,TUBB3,CHST15,FDFT1,ATP5PD,STAU2,FYN,IQGAP2,GPD2,GPER1,RNFT2,HAS2,PACSIN2,ATXN2L,INPP5B,KCND1,KCNN3,KIT,STMN1,SMAD1,MEIS2,AFF1,NCF2,NEFM,NRCAM,SERPINI1,PKM,GPSM2,PMP22,POLR2F,PRKACB,PRKCB,PRPH,SNRK,PTPRE,QDPR,RGS3,MAPK12,SBF1,SEC14L1,SLC2A5,SLC12A2,SMARCA4,IZUMO4,LMO3,POGZ,KIAA0930,SYNE1,SSBP2,ZKSCAN5,ATP6V0E2" Coexpression M2850 Genes up-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [Gene ID=3205] gene by RNAi vs controls. MSigDB C6: Oncogenic Signatures (v6.0) 1.88E-04 1.00E+00 3.91E-03 3.87E-02 39 194 "CLK4,GAS7,CD86,RCBTB2,PLAA,MAP4K4,ENTPD4,CSNK1G3,IPCEF1,VCAN,HDAC4,ZFYVE16,FBXL5,ANKRD46,FRY,KMT5B,RPS6KC1,ST3GAL6,FCGRT,TPK1,FYN,GALC,SESN1,IFI16,JAK2,NCF2,SNX10,SCHIP1,PTPRE,ROGDI,FNDC3A,SLC22A4,UHRF1BP1L,ARHGAP26,AGTPBP1,DICER1,ZMAT3,SGK3,PHTF2" Coexpression 20460542-SuppTable2 Human Colon_Dessein10_211genes GeneSigDB 1.88E-04 1.00E+00 3.91E-03 3.87E-02 54 296 "ASPHD1,ASIC1,ZNF608,AGT,SYT13,FAM131A,APOC1,CPNE5,CHRD,DST,COL9A3,GAL3ST1,SEC31B,ARHGEF10,VCAN,DZIP3,MYADM,DBN1,TIAM2,SEZ6L2,EDN1,FDFT1,PPP1R1B,FGFR3,SCARA3,SPECC1,RAB40B,GRB10,ITGA7,KCNH2,MARK1,NCF2,OPA1,PALM,PCSK5,PDE4A,PFKFB3,KCTD15,TATDN3,SLC26A11,GALNT10,ST6GAL1,IFT122,SSTR1,ZC4H2,COBL,THRA,TPM2,CCDC14,CLDND1,GDPD5,GJC2,FXR1,SENP7" Coexpression 12096084-Figure3-1 Human Breast_Jazaeri02_1430DownRegulated GeneSigDB 1.93E-04 1.00E+00 3.99E-03 3.96E-02 15 49 "AMPD2,NCOA1,NRP2,KALRN,ZFP28,SUGP2,GOLGA7,UFM1,SYT17,MMADHC,RPS6KA2,SCN2B,MAST1,TCF4,ZNF24" Coexpression 19286929-SuppTable2p Mouse Lung_Rangasamy09_55genes GeneSigDB 1.93E-04 1.00E+00 3.99E-03 3.96E-02 15 49 "ADD1,AMPH,KRIT1,CFL2,CLIP3,DMD,GPHN,PTK2B,GABARAPL2,SCIN,MYO6,MYO9A,TMOD2,ABLIM3,ACTR6" Coexpression M265 Up-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.97E-04 1.00E+00 4.05E-03 4.02E-02 21 82 "ADCY8,PTCH2,N4BP2L1,KSR1,ARHGEF7,CACNB4,ARHGAP33,ERBB4,CORO2B,FCGR1A,FGF1,GABRB3,DENND2A,NXPH3,KCNJ5,MYO7A,NNAT,PKD1,CNNM2,PCDHB6,PIK3R5" Coexpression M1278 Genes down-regulated in pulpal tissue extracted from carious teeth. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.97E-04 1.00E+00 4.05E-03 4.02E-02 21 82 "LGR5,CALB1,SLIT2,SPOCK3,DPP6,FGFR1,SESN1,GHR,GPR37,KIT,PCDH9,PLCL1,TMEM255A,ST8SIA1,PDZD2,PEG10,ZNF423,SYT1,TRIM2,TIAM1,ACTR3B" Coexpression 15374961-Table2 Human Brain_Freije04_44genes GeneSigDB 1.99E-04 1.00E+00 4.09E-03 4.06E-02 14 44 "HDAC4,EDNRB,CALCRL,DLL3,MSTN,CSDC2,ITPKA,NTRK2,CRTAC1,RGS4,SNCA,SYT1,SYT5,VSNL1" Coexpression 20630075-AF-3 Mouse StemCell_GarciaEscudero10_311genes_p53 GeneSigDB 2.00E-04 1.00E+00 4.11E-03 4.07E-02 44 228 "ACADM,NDRG2,ABCD2,BBOX1,MYOM1,ADAM23,BCHE,USP2,CDO1,AKAP6,GAL3ST1,PDE4DIP,EDN3,KATNAL1,MRVI1,TMEM132C,PDLIM5,GALNT15,IP6K3,TXNL4A,GPD1,GSN,COQ10A,ELOVL5,ITPKB,MBP,PGAM2,TMEM38A,FXYD1,MINDY2,NDUFS7,CLIP1,SATB1,SCN7A,SH3BGR,LIMS2,ADHFE1,TRIM2,TIMP4,TPM2,SYNPO2,ZIC1,PROCA1,WNK2" Coexpression M2228 Genes down-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.00E-04 1.00E+00 4.11E-03 4.07E-02 269 1972 "ABCF1,ACADM,ACTN1,ESYT2,ZNF608,MTUS1,AK2,SPOP,EP400,C6orf89,PARG,APAF1,KCNAB2,TNRC6C,USP37,ARNTL,ARRB2,EIF4G3,ATP1B3,STX16,RIPK1,DOCK11,BACH1,SEC11C,BCL7A,CFLAR,PROM1,SYNJ1,BTK,AP1M1,CALM1,CAMK2G,CAST,HIP1R,PRC1,CERS5,CCNH,LRRFIP1,COPB2,SRSF11,FOXN3,SOCS6,B4GALT6,RAB28,QKI,LY86,CNN3,ARMC8,SMARCAL1,SH2B1,AKAP12,RNF14,ANKRD44,NCOR1,NCOR2,GDA,CSF1R,CSF2RA,CSNK1G3,SIPA1L1,CST3,PNPLA8,PUM1,CYBB,RIPOR2,MAML1,IST1,DBI,GIT2,PITPNC1,ELMSAN1,ZBTB24,ELMO1,FBXL5,FAM107B,DOCK2,DPYSL2,PDCD6IP,DNAJB6,FARSB,TSPAN5,ANKRD46,HIPK3,FEM1B,FCF1,KLHL5,FRY,YAF2,EBI3,KMT5B,PLXNC1,IRAK4,CERCAM,USPL1,VPS13B,EPB41L2,GPHN,IGSF6,EXTL2,F5,TAOK3,FCGR1A,SEC24B,POLR1B,TMEM164,UBE2E3,PCYOX1,ANKFY1,NOP56,TMEM175,JKAMP,FAM49B,CAMKK2,CELF1,MSANTD4,MPP6,FYN,B4GALNT1,ZNF274,IQGAP2,ERAP1,CPLX2,TUBGCP4,SESN1,GGTA1P,BRD8,TXNL4A,TCERG1,RNPS1,DBF4,SPIN1,GLYR1,TNRC6A,MSL3,KDM2B,GPD2,ADAP1,CIT,GSN,MUM1,NCKAP1L,ELOVL5,ACOT7,HP,IRF8,MSL1,IDH3A,RBPJ,IL6R,INPP1,FAM69A,INPP5B,ITGAM,KIT,IPO5,STXBP5,LAMP2,STMN1,LMO2,MAN2A2,MARK3,MBD1,MBP,TM6SF1,MEF2C,AFF1,THYN1,MYO7A,HNRNPM,SFR1,NFYA,PDPK1,GNG2,FAM98B,PIK3R1,PSAT1,ING3,SH3KBP1,PPP2R5E,PPP3CA,PPP5C,PRKCB,FITM2,PTPRE,TTC13,TUG1,PPP2R3C,QDPR,C1orf54,RAP1GDS1,ROGDI,OXR1,RDX,ERI2,UBR7,DCUN1D2,SETD5,ATP8B4,RPS6KA2,CLIP1,NCBP3,SAFB,SCP2,SUPT20H,TRA2B,SCAF8,FBXO11,SEC31A,SLA,DHX30,BTBD7,ATF7IP,EPC1,TTC17,TMCC1,FNBP1,UHRF1BP1L,MYCBP2,TEX2,CDK19,ZBTB43,POGZ,SS18,SULF2,KLHL7,PRRC2C,SYPL1,ANKRD28,TACC1,TAF9,AGTPBP1,FBXW11,TBL1X,SIN3B,CLASP1,SYNE1,PUM2,ARHGAP9,SIK3,CYB561A3,DICER1,SIRT1,ZNF106,TIAM1,ACTR6,BHLHB9,TMPO,TP53BP1,TP53BP2,C9orf85,NR2C2,SGK3,EIF4ENIF1,USP1,VAV1,WIPF1,CLDND1,XPO1,ZBTB14,DHX33,INTS3,SLC38A1,MPPE1,DOCK8,KAT6A,HNRNPA3,RSPRY1,ZDHHC20,RNF146" Coexpression 18794102-TableS1 Human Breast_Yang08_840genes GeneSigDB 2.02E-04 1.00E+00 4.13E-03 4.10E-02 60 339 "ADRB2,C1QTNF3,ATP1A1,ATP1A3,ATP1B3,SGCE,C5,DDR1,PRC1,SLIT2,COL4A5,COL9A3,SLC4A8,CSF1R,DBN1,DMD,DOCK2,DNAJB6,ABCC5,EGFR,ERBB2,ABCA8,FGFR1,FGFR3,BAIAP2,ATP5PD,EVL,ATP6V1H,ATP2C1,GRB10,IGF1,JAK2,KIT,LAMA2,MAP4,MAPT,MATN3,SHC3,MID1,MSR1,MYH3,MYO5A,MYO6,PDPK1,FXYD1,CEP41,PTN,PTPRB,PTPRE,PTPRN2,ROBO1,SLC4A3,SPP1,DNAJC9,TEK,TRIO,TST,DNALI1,SEMA3B,RTN4" Coexpression 19351829-SuppTableC Human Lung_Daniel09_177genes GeneSigDB 2.02E-04 1.00E+00 4.13E-03 4.10E-02 34 162 "RALGAPA1,USP31,PKP4,PPP4R4,CASK,BMPR1B,DDR1,PCYT1B,COL9A3,MAGED1,RCHY1,CST3,ARHGEF4,GPRASP1,KIF19,SRPK3,PAN3,MFSD10,FGFR3,GPD2,ZNF496,MUM1,L1CAM,MYT1,PDPK1,TRHDE,CLIP1,ABTB1,CEP68,CLASP1,CABIN1,TRIO,RTN4,JMJD1C" Coexpression M5354 "Genes required for proliferation of DLD-1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.03E-04 1.00E+00 4.14E-03 4.11E-02 36 175 "NME5,TAOK1,ALK,STK33,BTK,KALRN,ARHGEF25,ARHGEF2,PICK1,AKAP7,AKAP6,CSNK1E,APPL1,DMPK,RPS6KL1,EPHB1,SPEG,TAOK3,FGFR3,FYN,DBF4,PACSIN2,PIK3AP1,NF1,PIK3R1,PKM,EXOSC10,PPARA,PRKACB,PRKAR1B,STK32A,FIGN,STK32B,HECW1,SYT5,TRIO" Coexpression M2806 Genes up-regulated in astrocytes. MSigDB C6: Oncogenic Signatures (v6.0) 2.11E-04 1.00E+00 4.29E-03 4.25E-02 24 100 "AGT,ABCD2,RGS20,ATP1A1,BMPR1B,CBS,HAPLN1,HEPH,CHRDL1,FGFR3,ATP13A4,GABRG1,AIFM3,GRIN2C,FRMD5,KCNJ16,GPR85,PPARA,ELOVL2,RORB,TNFRSF19,SLC6A11,LGI4,SPIRE1" Coexpression M2862 Genes in the blue cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.21E-04 1.00E+00 4.48E-03 4.44E-02 9 21 "BMPR1B,DCLK1,ERBB4,FGFR3,RET,NEK11,EPHA10,STK32B,MAP3K12" Coexpression 16546165-table5 Mouse StemCell_Williams06_23genes GeneSigDB 2.21E-04 1.00E+00 4.48E-03 4.44E-02 9 21 "NUMB,PROM1,EGFR,FGFR1,FGFR3,RBPJ,MSI1,PAX6,SOX3" Coexpression 18338247-SuppTable3 Human Breast_Harvell08_298genes GeneSigDB 2.25E-04 1.00E+00 4.55E-03 4.51E-02 38 189 "XKR4,AP2A1,BBOX1,APBB2,NUMB,SLC4A4,DST,CA12,ZFP28,MATR3,EPB41,OLFM1,SCARA3,SYNCRIP,PDLIM5,GNG4,PRDM5,IFI16,KITLG,MMP16,MYO5A,CLDN11,ENPP2,PFKFB3,ANKHD1,SALL1,SATB1,CPEB3,MCF2L2,LMO3,SYN2,TMEM121,CABIN1,STXBP4,PPIL6,TTC3,ZNF711,PROCA1" Coexpression M2004 Genes with intermediate-CpG-density (ICP) promoters bearing histone H3 K4 trimethylation mark (H3K4me3) in embryonic stem cells (ES). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.27E-04 1.00E+00 4.59E-03 4.55E-02 111 718 "SYN3,NCKAP5,NME5,C1QTNF1,ABCD2,AMH,ANK2,ATP6V1G2,TTLL9,ZNF599,LDHD,SYNJ2,CD38,TPP1,STOML1,AKAP7,PCYT1B,FAM149A,AKAP6,COL4A5,SUMF2,SMARCAL1,RTTN,DCAF4,KIAA0408,KATNAL2,TCAF1,DGKB,ELMO1,ALKBH8,SACS,CD99L2,SLC12A6,FIS1,KLHL5,FAM13A,MBNL2,AASS,ETV1,ABCA8,FAM198B,SCML2,SLC9B2,IP6K2,SYT3,TRIM16,TPPP3,BRSK1,TVP23A,MEGF10,TRAF3IP2,GHDC,ALDH1L1,ZNF276,PLPP7,SPACA9,GRIK5,CPT1C,HSPA1L,KCND1,LAMA2,LIFR,SYTL4,ASPRV1,EFHB,LINC00672,IDNK,P2RX7,PCSK1,GNG2,PGAM2,SERPINI1,HYDIN,WBP1L,ZIK1,RIPOR1,PPP2R3C,SH3TC2,ARMH4,FBXW7,ADAL,TRAPPC13,DGLUCY,CSRNP3,SH3BGR,SLC11A1,MTERF2,INTS9,FAIM2,TSNAXIP1,SPP1,PBLD,ZC4H2,ST5,ADHFE1,ARHGEF9,SYT1,SYT5,TPCN2,TRIM2,DOCK9,GPRIN3,TEK,ACTR6,SMUG1,ZKSCAN5,FTSJ1,DNALI1,MDH1B,TMEM63C,NHSL1" Coexpression M12027 Genes up-regulated in HCT8/S11 cells (colon cancer) engineered to stably express NTN1 [GeneID=1630] off a plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.27E-04 1.00E+00 4.59E-03 4.55E-02 8 17 "NRXN3,PLXNC1,TOX3,KITLG,RDX,FBXO11,FHOD3,SATB2" Coexpression M16496 Top 200 marker genes up-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.28E-04 1.00E+00 4.60E-03 4.56E-02 36 176 "ABHD6,AXIN2,ADRB2,SPARCL1,LGR5,AQP6,CDC14B,SLC4A4,SLC16A4,ABCG2,MYRIP,FAM169A,RHOBTB1,DYNC1I1,ECM2,TSPAN5,GPHN,FGF13,ALDH1L1,GLUL,FRMD3,HLF,NKD1,AQP11,SEPT4,FITM2,PTPRG,ACSS3,SALL1,TNFRSF19,NUBPL,SLC22A4,ANKFN1,RUNDC3B,AMACR,VLDLR" Coexpression 16488994-SuppTable1a Mouse Lung_Lu06_856genes_Array MG_U74Av2 GeneSigDB 2.34E-04 1.00E+00 4.69E-03 4.65E-02 75 449 "ADCY8,ADORA1,ADRB2,ALCAM,LTBP4,PKP4,ARRB1,NUMB,MPDZ,PROM1,LRBA,RAB28,PLAA,HOMER3,CNTN1,COL4A5,AKAP12,CSF1,CSNK1E,VCAN,EDN1,EGFR,RASGRP2,F5,FECH,FER,FGFR1,FHL1,FLT1,FYN,SESN1,GGT5,LYVE1,CRCP,FERMT2,LNX1,PCLO,STMN2,GUCY1B1,HP,IGF1,IL6ST,ITGA7,ITPKB,KCNH2,KIT,LAMA2,STMN1,MBP,MITF,MYO6,MYO7A,NBL1,P2RY1,PALM,PCSK5,GNG2,PMP22,RELN,PTPRB,PTPRD,PTPRE,ROGDI,RASGRF2,DPF2,RGS4,ROBO1,RPS6KA2,MRAS,SPP1,TNS2,PCDHA1,TEK,ZMAT3,ZNF106" Coexpression M3837 Down-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.34E-04 1.00E+00 4.69E-03 4.65E-02 88 545 "NDRG2,C1QTNF1,SEMA6A,LTBP4,AMPD3,AMT,OGT,GAS7,APOC1,ATP1B3,IL33,RGN,CDH2,DLGAP1,RCBTB2,CREM,CRHBP,ABCG1,CSF1,VCAN,CTH,RIMS2,CYBB,GPRASP1,HDAC4,RASSF2,SPOCK2,HEPH,SV2B,SGSM2,CHRDL1,EEF1D,EGR3,ST3GAL6,FGF12,FHL1,GABBR1,INPP5K,ALDH1L1,CSDC2,GGT5,POLL,LUZP2,KCNJ5,KCNK3,KCNN2,LAMA2,MEIS2,ADAM22,MYO7A,NBL1,ABCB1,DUSP26,FXYD1,PLTP,SEPT4,LRRN3,MAPK10,CNNM2,WBP1L,PTCH1,PTH1R,ACSM5,PID1,OXR1,KLHDC8A,BAALC,ZNF331,SCN7A,FERMT1,SIRT2,INTS9,TMCC1,PDZRN3,LHPP,CEP68,TEK,SIRT1,TK2,KAT6B,TNS1,UBTF,LMF1,VSNL1,FTSJ1,SEMA3B,FAM182B,ADAMTSL3" Coexpression M5942 Genes down-regulated in response to ultraviolet (UV) radiation. MSigDB H: Hallmark Gene Sets (v6.0) 2.36E-04 1.00E+00 4.72E-03 4.68E-02 31 144 "SPOP,AMPH,CDC42BPA,APBB2,CDK13,SYNJ2,CACNA1A,KALRN,SIPA1L1,YTHDC1,NR1D2,CDON,ERBB2,DLC1,PDLIM5,ATP2C1,FYN,HAS2,ICA1,KIT,MMP16,PMP22,SCHIP1,RGS4,RXRA,SCN8A,SCAF8,WDR37,ARHGEF9,SYNE1,VLDLR" Coexpression M3835 Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [GeneID=6657] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.36E-04 1.00E+00 4.73E-03 4.69E-02 113 734 "AP2A1,OSBPL1A,SEMA6A,ALCAM,OGT,CDC42BPA,PARG,CDC14B,RASL11B,TMEM108,ALDH7A1,RIPK1,BMP7,CA4,CACNA1A,CACNA2D1,SPAG9,CDH2,LARGE1,FOXN3,B4GALT6,CNOT8,RBM39,RNF14,CSNK1E,VCAN,CTH,PUM1,HDAC9,TCAF1,KIF26A,TMEM170A,HEPH,LYPD1,GUCD1,MED12,DPYSL2,ACOT8,DTNA,AASDH,KLHL5,SUGP2,APH1A,EGR3,EIF4G2,ING4,ERBB2,PIPOX,FGFR1,UFM1,TRIM16,OGA,TNRC6A,MSL3,KCNMB4,DIDO1,FICD,LINGO1,HAS2,IFI16,KCNN2,PAXBP1,HECTD2,XRRA1,MYO9A,PCSK5,ENPP2,MINDY2,PPM1B,CEP41,ANKHD1,PTN,ZIK1,ZSCAN2,PPP2R3C,C1orf54,RASGRF2,RIC8B,RPL15,ZNF331,RMI1,DGLUCY,SALL1,SH3GL3,FBXO11,MAST1,RCOR3,SNRPN,KDM3A,SP2,LHPP,ZC4H2,KANK1,TAL1,FBXW11,OBSL1,SLC44A1,TIMP4,CBX5,FAM124A,SGK3,UBC,UGT8,ZIC1,ZIC2,SPIRE1,SMARCAD1,MAP3K12,URM1,FIP1L1,FZD3,MRPL47,KAT6A" Coexpression M2186 "Genes down-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.42E-04 1.00E+00 4.83E-03 4.79E-02 33 157 "PLEKHH1,INSYN2B,ATP1A1,KSR1,BMPR1B,CBS,SRSF11,RAB33A,PPT2,AKAP7,GREB1,MFAP3L,USP3,ARRDC4,DUSP9,RACK1,FDFT1,OLFM1,SUCO,FAM49B,GPD2,LIFR,LYRM9,NPR2,PCDH18,MAPK9,MASP1,ELOVL2,SUSD4,MEG3,MAPKBP1,CHST8,RGS7BP" Coexpression M2168 Cluster 3 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.43E-04 1.00E+00 4.84E-03 4.80E-02 35 170 "SPOP,PCDHGB4,ZNF582,BCL7A,NRP2,ZNF501,KCNAB3,ZFP28,CRHBP,PYGO1,MATR3,ZBTB45,GUCY1B1,IDH3B,ZIC5,NIM1K,NFIX,NNAT,GLIPR1L2,PCDHB17P,CEP41,HKR1,BTBD3,ZNF667,PCDHGB7,PCDHGA11,PCDHB10,PCDHB9,TEK,BHLHB9,PRR18,ZBTB14,ZNF154,MSRB3,GAN" Coexpression M5775 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 12 h time point that were not down-regulated at the previous time point, 10 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.48E-04 1.00E+00 4.92E-03 4.87E-02 24 101 "RUNX1T1,LDB2,SIPA1L1,NR1D2,ECM2,MAMLD1,TSPAN5,VPS13B,LRRC17,ERCC2,DLC1,OGA,FYN,HMGCL,INPP5B,MID1,PMP22,ZNF415,ST5,MTCL1,TRIM2,FLRT2,ZIC1,TUBA1A" Coexpression M15780 Down-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.48E-04 1.00E+00 4.92E-03 4.87E-02 24 101 "LRFN1,CBS,LDB2,CACNA2D2,COL4A5,GREB1,SIRPB1,CHST15,FHL1,C2orf88,TOX2,ITPKB,SCAMP5,MITF,MYCN,PRKACB,PRRT2,NUDT11,ST6GALNAC6,SNCA,UNC5B,CHST8,TRPS1,SLC30A3" Coexpression 18698033-tableS1-ESR1 Human Breast_Desmedt08_469genes_ESR1_Module GeneSigDB 2.50E-04 1.00E+00 4.96E-03 4.92E-02 75 450 "ABCF1,FZD9,NME5,SPOP,ALCAM,SYT13,BIN1,APBB2,BCAS1,PROM1,CA12,CBS,LRBA,CLGN,EPS15L1,RAB26,COL9A3,LRIG1,KIAA0040,KIAA0753,SACS,RCAN1,EGR3,ERBB4,NCALD,ZMYND10,UBE2E3,EVL,KHDRBS3,GPR162,GPR37,GRIA2,PTPRT,FAM107A,GUCY1A1,ELOVL5,IL6ST,MARK1,N6AMT1,PCDH8,RETREG1,WDR25,ELOVL2,PTPN13,PTX3,QDPR,ROGDI,RIC8B,EXD2,SATB1,FNIP1,FAM102A,KIF16B,SYBU,ABLIM3,SEPHS1,CDK5RAP3,SLC22A4,SOX11,NEK4,KLHL7,ASTN2,TRIM2,TP53BP2,CDK20,SSBP2,UCHL1,UGT8,VLDLR,ZIC1,DNALI1,SLC38A1,HRASLS,ACTR3B,IFT88" Coexpression M17026 Genes up-regulated in three-dimentional (3D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.51E-04 1.00E+00 4.97E-03 4.93E-02 41 210 "AMT,APC,ASGR1,ATP2A2,NAE1,C5,CAPN3,RUNX1T1,KYAT1,CCK,DCLK1,TAOK2,EPS15L1,RAB33A,STOML1,FAM189A2,AKAP5,CSF1,DCTN1,DMD,HIPK3,CDKL3,ZMYND10,FGF12,FGFR1,INPP1,MMP17,PTK2,PTN,QDPR,RFX3,RYR3,CASC3,SST,TCF12,GPR161,CHST5,SSBP2,ZNF32,FTSJ1,ST7" Coexpression M1949 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.55E-04 1.00E+00 5.03E-03 4.99E-02 61 349 "KCNH8,XKR4,GALNT13,ALK,DPP10,SEMA7A,VAT1L,CPNE5,CADPS,ATP2B2,ADGRB1,HCN2,CACNA1I,CABP7,DLGAP2,CLGN,NOG,CACNA2D2,CHRNA4,SULT4A1,MYRIP,C1QL2,ABCG1,RGS6,RASGEF1C,KCTD8,CNNM1,TMEM132E,FOXF2,CPLX1,GNG4,PTPRT,NXPH3,IGFBPL1,SHISA6,SLC6A17,KCNK3,NEFH,VWA2,PPP2R2C,PRPH,LAMA1,PTPRN2,IQSEC3,RASGRF1,CRTAC1,RET,PLPPR3,STUM,MAST1,CLSTN2,STAC2,TMEM150C,COBL,PHF24,FAM155A,RBFOX3,KCNK12,SLC30A3,DOCK8,JPH3" Coexpression 18849563-SuppTable5c Human Lung_not_cancer_Bhattacharya09_84genes_ FEV1PercentPredictedinCOPDAllSubjects GeneSigDB 2.57E-04 1.00E+00 5.04E-03 5.00E-02 19 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,UBTF,ZNF23,ZNF177" Coexpression 18849563-SuppTable4 Human Lung_not_cancer_Bhattacharya09_84genes GeneSigDB 2.57E-04 1.00E+00 5.04E-03 5.00E-02 19 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,UBTF,ZNF23,ZNF177" Coexpression 18849563-SuppTable5b Human Lung_not_cancer_Bhattacharya09_84genes_FEV1PercentPredictedorFEV1/FVC GeneSigDB 2.57E-04 1.00E+00 5.04E-03 5.00E-02 19 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,UBTF,ZNF23,ZNF177" Coexpression 17597811-SuppTable5 Human Leukemia_Mullighan07_744genes GeneSigDB 2.58E-04 1.00E+00 5.06E-03 5.01E-02 95 599 "ABR,ADRB2,OSBPL8,AK2,BEGAIN,BIN1,GAS7,DYNLL1,BID,RAB29,WASF1,BAIAP3,CA4,CALM1,HIP1R,RUNX1T1,PPT2,TPP1,CLTB,HOMER3,CLIP3,CSF2RA,IPCEF1,SIPA1L1,PPP1R16B,RASSF2,DAPK1,ELMO1,RCAN1,EEF1D,EGR3,PLXNC1,SIRPB1,ABCA8,PTK2B,DLC1,FCGR1A,FDFT1,SEC23B,STAMBP,RASL10A,ATP2C1,ZNF274,GGT5,MALT1,BRD8,HPGDS,GLYR1,LILRB4,LILRA2,HLF,IRF8,IL6R,ITGA7,MBNL1,MEIS1,NBL1,NINJ2,NOVA2,OGG1,OPRL1,CYTL1,OLA1,ABCB1,SNX10,PKM,PILRA,NDUFS7,RIPOR1,RBBP8,GTDC1,NUDT11,BAALC,ATP8B4,STK32B,RXRA,ASAP3,SLA,ARHGEF40,SLC12A4,SOX11,ZSWIM8,NXT2,MCF2L,TAL1,IQCE,KIAA0930,TK2,TTC3,LAT2,SH3GLB2,TRIM16L,MPPE1,JMJD1C,NLRP3" Coexpression M13714 Down-regulated genes displaying alternative splicing in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.59E-04 1.00E+00 5.08E-03 5.03E-02 14 45 "CLK4,NAE1,COL9A3,TSPAN5,EIF4G2,TTBK1,ADAMTS13,MAPT,PDCD2,PTK2,SPP1,PCDHAC2,PCDHA5,SEMA3B" Coexpression M4662 Genes down-regulated in comparison of PD-1 high CD8 T cells versus PD-1 low CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.61E-04 1.00E+00 5.10E-03 5.06E-02 39 197 "NDRG2,TMCC3,CARNS1,PITPNM2,GAS7,ARRB1,LDHD,SEPT7,TMEM184B,PLXNA4,KATNAL2,JAKMIP2,USP3,FRY,TENM1,RGS17,NCALD,CD320,IQCG,SPECC1,GLUL,GPER1,ACOT7,LRRCC1,ITGAM,PIK3AP1,TM6SF1,TBC1D25,PDE4A,PRKACB,USP47,ATP8B4,RXRA,LIMCH1,ZMAT3,TLR4,RUNDC3B,LAT2,FRMD6" Coexpression M7287 Genes down-regulated in monocytes: control versus HCMV infection. MSigDB C7: Immunologic Signatures (v6.0) 2.61E-04 1.00E+00 5.10E-03 5.06E-02 39 197 "ADCY5,ADD2,OLMALINC,MTA3,MPDZ,FOXN3,MROH8,PUM1,CYBB,ECM2,FAM78B,EPB41,KAT8,FGF11,POLK,PSD2,ZBED3,RASL10A,GABRG1,MAN1B1,HMGCL,BEX5,NTRK2,PRTG,ZFHX4-AS1,PRKAB2,ASAP3,IFT122,CLASP2,SEPT8,ANKRD12,ZFP90,PCDHGB7,PCDHGA10,CBX5,ZNF346,SSBP2,ZNF19,ZFAND5" Coexpression M1535 "Down-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls" MSigDB C2: CGP Curated Gene Sets (v6.0) 2.63E-04 1.00E+00 5.13E-03 5.09E-02 13 40 "ACHE,ATP2A2,CAMK2G,MAGED1,CS,DNM1,VTI1B,PRKACB,SARS,DHX30,SYT1,UBC,VSNL1" Coexpression 18410693-TableS8 Human Leukemia_Kiiveri08_100genes_TEL-AML1Tree GeneSigDB 2.64E-04 1.00E+00 5.13E-03 5.09E-02 17 61 "HAP1,B4GALT6,ABCG2,ARHGEF4,NRN1,FYB1,IQGAP2,PCLO,KCNN1,STMN1,NOVA1,PRKCB,EPN2,SLC12A2,ZNF423,TNS1,SH3GLB2" Coexpression 17023574-TableS1 Human BoneMarrow_Zhan07_2181genes GeneSigDB 2.68E-04 1.00E+00 5.20E-03 5.16E-02 230 1663 "CLK4,ADD1,PWWP2A,AP2A2,ALCAM,OGT,PKP4,APC,CPNE5,CDK13,ZBTB10,CHID1,ATP1A1,BID,CFLAR,DST,ST3GAL5,CALM1,CAST,CARS,CCNH,CCNT1,USP6,ARHGEF2,DIS3L,FOXN3,SOCS6,RAB28,PLAA,HECTD1,AKAP7,COX4I1,AHCTF1,NSL1,FAM171B,PREPL,ENTPD4,ANKRD44,NCOR2,CSNK1E,OSBPL3,SOCS5,CST3,DZIP3,KIAA0040,PHF14,PUM1,RUBCN,HDAC9,MYADM,GAPVD1,MATR3,KIAA0586,YTHDC1,MFAP3L,POM121,SEC16A,USP3,NR1D2,CPEB2,DMTF1,FIS1,RASGRP1,EEF1D,KMT5B,GOLGA7,EIF4G2,EIF5,EIF1,PTK2B,ST3GAL6,FDFT1,ATP5PD,UBE2E3,SYNCRIP,FOXO3,JKAMP,NBEA,PDLIM5,ATP6V1H,CELF1,SARAF,AP4B1,OGA,ZMAT1,ZNF44,RAPGEF6,SEPT9,BRD8,TCERG1,DBF4,RAB30,TNRC6A,MSL3,ZNF638,RAB40B,PSIP1,MUM1,MIER3,ELOVL5,AGFG1,IFI16,RBPJ,TJAP1,IL6ST,IPO5,KTN1,MAN2A2,MAP4,LYPLAL1,MAT2A,MBNL1,CHIC1,MEF2C,SCAMP5,POC1B,MKLN1,MYO6,HNRNPM,NEK1,ZNF827,ETFRF1,PDE4B,FAM98B,OLA1,ZNF655,CCSER2,XRN1,PLCL1,PLTP,PSAT1,ING3,PILRA,POLG,POLR2F,PPARA,PPM1B,PRKCB,NDUFS7,VPS13C,PTCH1,ANKHD1,PPP2R3C,USP47,RIC8B,PBRM1,GSTCD,YY1AP1,ELP2,RPL15,FBXW7,RPS6KA2,RPS20,SAFB,ATXN7,FNIP1,TRA2B,COPZ1,SGK1,KIF16B,SHMT2,FBXO11,PEX26,BTBD3,FAM214B,CDK5RAP3,KBTBD4,SLC12A2,TET1,CPEB4,SMARCA4,TTC17,USP33,BDP1,KDM3A,SP4,MYCBP2,RBM26,TROVE2,STAU1,KANK1,ZC3H4,PRRC2C,SYNE2,VPS13A,AGTPBP1,FBXW11,TCEA1,TCF4,TPCN2,TCF12,PUM2,SIK3,CYB561A3,RP9P,ZMAT3,ZNF34,ACTR6,LRRC8A,FAM124A,R3HDM1,METTL3,PDSS1,AMACR,RPL7L1,UBE2H,UBE3A,UBTF,UGT8,USP1,TOM1L2,CCDC14,RICTOR,XPO1,XRCC4,ZNF711,ZNF24,ATP6V0E2,ZBTB38,ZFAND5,MFF,SLC38A1,URM1,FZD3,MRPL47,DOCK8,RTN4,HNRNPA3,FXR1,NETO2" Coexpression M2148 Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.69E-04 1.00E+00 5.21E-03 5.17E-02 37 184 "FZD9,MTUS1,TNRC6C,CDC14B,ATP1A1,FUBP1,PRC1,AP4M1,CRYBB1,GREB1,PUM1,GPSM1,EBF1,PHF20L1,SYNCRIP,TUBA8,TOX3,SOX21,INSM1,NELL2,NOVA2,PCDHGC3,PCDH18,IRX1,PTPRN,PTPRO,KCTD17,PGBD4,HES6,SOX3,SOX11,KDM3A,HEY1,TMPO,ZIC2,ZNF184,ST8SIA2" Coexpression 17099726-SuppTable1 Human Breast_HernandezVargas07_313genes GeneSigDB 2.75E-04 1.00E+00 5.33E-03 5.28E-02 45 238 "MTA3,AGT,N4BP2L1,ADGRB3,BCHE,ST3GAL5,GYG2,CRLF1,ABI3BP,CRYM,CSF1,VCAN,DAPK1,ELMO1,DPYSL2,ARRDC4,FIS1,EDNRB,RASGRP1,DLC1,FOLH1,IQGAP2,GHR,HLF,HSPA1L,IRF8,IFI16,MITF,PIK3R1,MBOAT7,LAMA1,RASGRF1,SGK1,FBXO11,SLC6A8,SPP1,TACR1,ZFP90,PCDHA6,SLC35G2,PARD3,SSBP2,VLDLR,WRN,PPP1R3F" Coexpression M2143 Genes down-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.81E-04 1.00E+00 5.44E-03 5.39E-02 26 114 "AMPH,MYRF,LDLRAD4,PHACTR3,BOC,HDAC9,SNAP91,EDNRB,AASS,FOXO3,GFRA2,FREM1,RNF165,MATN2,MMP16,NTRK3,PCDH18,NECAB2,ROBO2,SATB1,ST8SIA1,ZNF423,SSTR2,ADGRL3,FAM124A,ST8SIA2" Coexpression M15148 Genes down-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.87E-04 1.00E+00 5.53E-03 5.48E-02 25 108 "PRX,MPDZ,CLTB,CPEB2,FDFT1,FGF1,HMGCR,ITPKB,LSS,MBP,NRBP2,ABCB1,PIK3R1,PMP22,RAP1GDS1,EMID1,RTN1,S100B,SCN7A,SIRT2,LIMCH1,SNCA,NACC2,UGT8,SEMA3B" Coexpression 16491124-SuppTable1 Human Breast_Doane06_145genes GeneSigDB 2.90E-04 1.00E+00 5.58E-03 5.53E-02 24 102 "KIAA1324,ALCAM,AZGP1,BMPR1B,CA12,CLGN,SLC4A8,GREB1,ERBB4,EVL,SYT17,TOX3,MAPT,MYO6,ELOVL2,RET,STK32B,SYBU,IFT122,CLSTN2,SYT1,MAP3K12,DNALI1,SEMA3B" Coexpression M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.90E-04 1.00E+00 5.58E-03 5.53E-02 51 280 "ADD2,SRPX,PCDH10,VAT1L,CASK,TMEM108,CA4,CA12,LRRFIP1,ZNF521,ANKRD44,SIPA1L1,VCAN,BOC,EDIL3,HIPK3,FRY,PCYOX1,IQGAP2,GHR,COPS8,GRB10,GSN,TOX2,NEGR1,LIFR,LIMS1,MATN2,SAMD5,ALDH1L2,NTRK2,OXTR,GNG2,PMP22,PTPN13,PTX3,RASGRF2,RTN1,TNFRSF19,FAM102A,UNC5B,MCF2L2,ST5,SULF2,PLCB1,PCDHB10,SLC44A1,VLDLR,ZNF711,MFF,PLSCR4" Coexpression M8147 Genes up-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 2.91E-04 1.00E+00 5.58E-03 5.54E-02 39 198 "NME5,APOC1,RASL11B,ATP2A2,ADGRB2,THSD7A,KRIT1,CDH2,DCLK1,LARGE1,FHL5,COX4I1,SIPA1L1,ZNF337,YTHDC1,VPS13B,PTK2B,ARFIP1,STMN2,SLC2A6,MAN1B1,LSS,MKLN1,NCAM2,OPA1,SEPT4,PTPRD,RGS12,INAVA,SOX11,STX1A,TAF9,FBXW11,CHST5,ZNF154,PRDM10,UBE3B,PHTF2,JPH3" Coexpression 20368555-TS-1 Human Breast_Barry10_1022genes GeneSigDB 2.93E-04 1.00E+00 5.60E-03 5.55E-02 123 815 "RALGAPA1,ADCY6,ADD1,NME5,BBOX1,AMPD2,APBA2,APBB2,CHRD,ATP1B3,ADGRB2,BID,BLM,CFLAR,PROM1,NAE1,WASF1,CA12,PRC1,CBS,LRBA,CDC25B,IQCK,COL4A5,LETMD1,COX4I1,LRIG1,OSBPL3,IPCEF1,CST3,KIAA0040,GREB1,ARHGEF4,DCAF8,DAPK1,FBXL5,CASP8AP2,GOLT1B,FRY,KCTD3,LRRC17,ERBB4,GMPR2,CHST15,ZMYND10,UBE2E3,SYNCRIP,EVL,NOP56,FOLH1,ATP2C1,MTHFD2,SYT17,TUBGCP4,ARFIP1,DBF4,MSL3,GLUL,PTPRT,PADI2,ELOVL5,HMGCL,IL6ST,STMN1,MAPT,NF1,NOVA1,PALM,PAX6,PDE4A,RETREG1,GPSM2,SMOX,PLXNB1,PMP22,PSAT1,RETREG2,DEF8,WDR25,ELOVL2,NKAIN1,QDPR,RAD17,ROGDI,NEK11,ZC3H14,MCMBP,STK32B,ATXN2,GALNT10,MRAS,KIF16B,SYBU,ABLIM3,SLC2A5,ATF7IP,IFT122,KDM4B,SOX11,GLT8D1,DBNDD2,SPTAN1,CLSTN2,POGZ,KLHL7,ARHGEF9,DNAJC9,AGTPBP1,TNS2,GPR161,R3HDM1,TP53BP1,TP53BP2,PDSS1,TRPS1,USP1,NPDC1,SH3GLB2,MAP3K12,DNALI1,SEMA3B,UBE3B,IFT88" Coexpression 15902281-TableS1c Human Leukemia_Schoch05_530genes GeneSigDB 2.93E-04 1.00E+00 5.60E-03 5.55E-02 43 225 "N4BP2L1,ARHGEF7,CLDN10,DCLK1,RCBTB2,SLITRK5,SACS,EDNRB,FRY,MBNL2,USPL1,FGF14,FLT1,NBEA,UFM1,PCDH17,GPR12,SOX21,IPO5,LIG4,SMAD9,PCDH8,PCDH9,ENOX1,DCUN1D2,TNFRSF19,SUPT20H,RASA3,FNDC3A,DZIP1,MYO16,MYCBP2,ZC3H13,RBM26,SPART,THSD1,MCF2L,DOCK9,NACC2,PCDH20,ZIC2,UPF3A,IFT88" Coexpression M14242 Genes trans-regulated by the same QTL (quantitative trait loci) in brain and hematopoietic stem cells (HSC). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.01E-04 1.00E+00 5.74E-03 5.69E-02 37 185 "NCOA1,BLM,SGCE,ZMYM4,EPS15L1,ZFYVE16,DNAJB6,ASB3,EIF4G1,STMN2,IGFBPL1,HP,KCNN1,MKLN1,MMP17,MOV10,MSI1,NRBP2,MYH3,SFR1,NEK1,NF1,EPB41L4B,PPARA,PKIA,PSD,RAP1GDS1,ST8SIA1,TTC17,KLHL7,SYPL1,USP22,NSD1,UBC,TBC1D15,ZBTB14,MAP3K12" Coexpression 17483317-TableS5 Mouse Bone_Boylan07_823genes GeneSigDB 3.03E-04 1.00E+00 5.78E-03 5.73E-02 99 632 "ALCAM,FAM135A,GAS7,LGR5,SFMBT2,CASK,ZBTB10,ATP6V0A1,BACH1,BCL7A,KSR1,ST3GAL5,FUBP1,PTBP2,SCARB1,CDH2,B4GALT6,CNN3,MAGED1,ABI3BP,AKAP12,GDA,LRIG1,OSBPL3,IPCEF1,PPP1R16B,CTH,CYBB,ARMCX2,GSDME,FARSB,EBF1,FAM13A,GPHN,STX2,IGSF6,EZH1,CORO2B,CHST15,OLFM1,NBEA,CINP,SARAF,MPP6,FYB1,RAPGEF6,IQGAP2,GATM,IGSF5,BRD8,RAB30,CBX1,LPAR4,GSN,DDX19B,BACH2,HP,ITGAM,KIT,LIFR,SMAD1,MARK3,NEFH,NFIX,NFYA,SETD4,PDE4D,ZFYVE21,LRP12,PRKACB,GRAMD1C,DIRAS2,PRODH,PTK2,PTPRE,OXR1,KIF7,EMID1,ATAT1,CLIP1,PPM1E,CPEB3,CCDC88A,EPC1,SNAP25,KIF13A,PDZD2,SPP1,ARHGAP26,CLASP2,CEP68,STXBP1,AGTPBP1,TRIM2,TIAM1,MTCH1,AMZ1,SPIRE1,EPM2A" Coexpression M2506 "Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.05E-04 1.00E+00 5.80E-03 5.75E-02 31 146 "ALCAM,ARHGDIA,BCHE,NRP2,RUNX1T1,CHN2,CNR1,HAPLN1,EDNRA,RASL12,DLC1,MSTN,STMN2,GSN,IFI16,KCNN2,L1CAM,MEF2C,MITF,TAGLN3,NEFM,NNAT,PCDH8,PMP22,LRRN3,SNAP25,SPP1,NFASC,SST,PCBP4,ST7" Coexpression M29 Genes whose expression positively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.13E-04 1.00E+00 5.95E-03 5.90E-02 71 424 "OSBPL1A,OSBPL8,MAP4K3,PKP4,APC,NCOA1,NUMB,SCAPER,CAST,KRIT1,SOCS6,RAB28,ARMC8,PREPL,RNF14,NCOR1,MATR3,YTHDC1,FBXL5,DDX46,FEM1B,COPS4,DCTN4,GMPR2,SEC24B,ARFIP1,NFU1,COPS8,CBX1,HTATSF1,RAB40B,STON1,MAP4K5,HNMT,SMAP1,RBPJ,KTN1,NF1,MAPK9,VPS13C,RDX,DPF2,PCMTD2,SCAF8,FBXO11,BTBD3,SEPHS1,ELMO2,RCOR3,LIMCH1,ZNF415,LMBRD1,RBM34,ZC3H13,TROVE2,ZNF302,SS18,STAU1,KANK1,NSFL1C,FBXW11,ATMIN,PUM2,AKTIP,BEX4,TSN,USP1,XPO1,UPF3A,HNRNPA3,RNF146" Coexpression M1973 Genes up-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [GeneID=9589] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.16E-04 1.00E+00 5.98E-03 5.93E-02 54 302 "KIAA1211,ARRB1,MARCH3,ADAM23,ST3GAL5,KALRN,NPIPA1,FOXN3,CHN2,RAB33A,TPP1,LETMD1,C2CD2,ENTPD4,CSF1,PITPNM3,NR1D2,SNX29,EDNRB,SH3YL1,ZSCAN30,FLT1,TRIM16,ATP2C1,ERAP1,GCNT2,PCDH17,PARD3B,FRMD3,HNMT,ZNF678,INPP1,ZNF667-AS1,SLC11A2,ETFRF1,ZNF655,SMOX,PMP22,SH3KBP1,PRKAB2,KIF16B,ANKRD6,LIMCH1,PDZD2,ARHGAP26,ZNF302,ZSCAN29,ANKRD12,PCDHGA4,FAM200B,HEY1,BHLHB9,VLDLR,NDRG4" Coexpression M8361 Genes up-regulated in T reg: natural versus induced cells. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "ADORA1,SEMA6A,SRPX,AQP6,EIF4G3,ATP6V1G2,ADGRB3,BTK,SCAPER,CAMK2A,ENTPD2,CLGN,AATK,DGCR5,DTNA,ERBB2,ERBB4,EXTL2,GABRB3,RAB30,TOX3,PRUNE2,GRM8,MN1,PCSK5,SCHIP1,CNNM2,PTPRD,EXD2,PPM1E,SLC22A4,PDZD2,CDK19,DMXL2,PCDHA3,THRA,FAM155A,FLRT2,AP3B2" Coexpression M5422 Genes up-regulated in comparison of eosinophils versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "OSBPL8,GAS7,MARCH3,MTMR3,LRRFIP1,DLGAP1,CLOCK,PITPNM3,TBC1D5,DBT,NR1D2,DMTF1,EIF4G2,CHST15,UBE2E3,USP19,LILRA2,GPR12,GRIA2,PRDM5,IL6R,INPP5B,KIF5A,KIT,MEIS2,NFE2L2,NME4,PPM1B,PTPRE,ROGDI,SMPD3,SUPT20H,FAM102A,BTBD7,ERBIN,PDLIM2,KLHL4,HIF3A,TLR4" Coexpression M8163 Genes down-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "ABCF1,ADCY8,AMPD2,LDLRAD4,SLC25A14,ARHGAP33,CSNK1E,MAMLD1,E2F6,GAD1,RUNDC3A,LUZP2,GPER1,HSPA1L,C2orf72,KCNF1,MEF2C,NINJ2,MAPK3,BEND5,RXRA,CPEB3,PPP4R3A,SLC22A4,USP33,UNC5B,SEPT8,SYN1,SYT1,DNMBP,AGTPBP1,AP4E1,ZNF106,AKTIP,NACC2,ZBTB14,UPF3A,MPPE1,ADAMTSL3" Coexpression M5009 Genes up-regulated in comparison of myeloid dendritic cells (mDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "KIAA1324,SEMA7A,APOC2,CASK,ATP6V0A1,WASF1,IL33,THSD7A,TAOK2,LHX2,TPP1,ENTPD4,SLITRK5,IP6K1,GSDME,TUBD1,SEMA4D,TRAF3IP2,HIGD1B,NEU3,GPR162,PRRC2B,SYNPO,PKIA,PTPN13,GAL3ST4,TCP11L1,SYBU,RCOR3,ZNF423,MCF2L2,EXOC7,PCDHB6,ZMAT3,RPRM,UBTF,ZNF37BP,FXR1,RNF146" Coexpression M9547 Genes up-regulated dendritic cells: Ly6G+ versus Ly6G-. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "KDM5D,AMT,CDC42BPA,CASK,NCOA1,SLC2A11,ATP6V0A1,NPIPA1,NDST3,SEC31B,CLOCK,ENTPD4,ABCG1,OSBPL3,ZNF337,SGSM2,NR1D2,ANKRD46,GMPR2,EZH1,TRMO,RAPGEF6,ZNF276,GPR75,GRB10,GUCY1A1,PACSIN2,ITGAM,MAN2A2,MXI1,LYRM9,RNASEL,SATB1,TSPYL2,ZNF302,TIAM1,TP53BP1,PCBP4,KAT6A" Coexpression M6651 Genes up-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL6 [GeneID=3469] and LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "ADCY6,LRCH2,ARHGDIG,ZBTB10,HCN2,C4orf33,SLITRK5,DCTN1,CD99L2,EDNRB,FEM1B,SUGP2,ARMCX1,ATP6V1H,KHDRBS3,CGREF1,NSG1,CYP46A1,GNAO1,GRIA2,UBE2QL1,CPT1C,LRRCC1,MYO6,NBL1,VWA2,PNMA3,PPP2R5E,LAMA1,STK32A,LGI2,MAP6D1,KIF21A,ZHX3,SEPT3,GPRIN3,ICAM5,FAM47E,FAM181A" Coexpression M4221 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h versus the untreated cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "OSBPL1A,USP35,AMPH,UPRT,NRP2,ZMYM4,LRWD1,CHN2,CLCN3,CTH,MTX3,RCAN1,FAM13A,PHF20L1,ENPP6,DLC1,SUCO,FYN,NFU1,RAB30,ADGRA3,MIER3,FAM69A,PLCL1,MBOAT7,EPDR1,NCR3LG1,PTPRE,ZMAT4,SATB1,CNKSR2,SP4,UHRF1BP1L,C12orf76,DMXL2,CUX2,TPM1,SSBP2,RNF146" Coexpression M4539 Genes up-regulated in comparison of CD8 T cells with progressing HIV infection versus those with controlled HIV infection. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "ADRA1D,APBA2,CHRD,CCNH,IP6K1,SPATA2,SEMA3D,EEF1D,EIF1,RRAGB,NBEA,SESN1,LILRB4,TDRKH,SOX21,MATN2,NBL1,NELL2,ABCB1,PRKAB2,PKIA,PPP2R3C,KLHL11,EXD2,GSTCD,RTN1,S100B,TRA2B,FAM102A,HKDC1,KIF13A,PBLD,JMJD6,SYPL1,TSN,SSBP2,TUBB2A,ITM2C,ST7" Coexpression M7718 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 1h. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "SPTBN4,CACNA1I,CAMK2A,SYNGR3,ARHGAP33,LARGE1,MAGI1,PICK1,CSF1,DAPK3,DPP6,STX2,FDFT1,PRKAG2,NEU3,GSTM5,IL6R,KCNJ5,KCNN1,KCNQ3,HNRNPM,NEFH,NLE1,SUSD4,RFX2,GSTCD,SEC14L1,ARHGEF40,CDK5RAP3,LIMCH1,IZUMO4,ARC,CAMTA1,TCF12,CRTC1,TP53BP2,CFAP298,ZNF142,TUBA1A" Coexpression M5566 Genes up-regulated in comparison of basophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.24E-04 1.00E+00 6.04E-03 5.99E-02 39 199 "N4BP2L1,BID,CALM1,ARHGEF10,SOCS5,CYBB,ZFYVE16,RASSF2,GIT2,PDCD6IP,EIF1,ST3GAL6,GALC,HP,KIT,MBP,SHC3,PIK3C2A,CCSER2,LRP12,PILRA,PTPRE,PTX3,DCUN1D2,SUPT20H,CPEB3,R3HDM2,SLC4A3,CDK19,POGZ,PLCB1,AGTPBP1,BEX4,TPM1,TSC1,CLIP2,GDPD5,ZNF37BP,TIGD6" Coexpression 20013794-Table3 Human CardiacCells_Haag09_64genes GeneSigDB 3.26E-04 1.00E+00 6.07E-03 6.02E-02 17 62 "SGCE,CAPN3,DMD,EGR3,ERBB2,SPEG,FHL1,PDLIM5,BVES,ITGA7,LAMA2,MBNL1,MEF2C,TAGLN3,MAPK12,MRAS,TCF12" Coexpression M17794 Down-regulated genes associated with poor survival prognosis of patients with metastatic neuroblastoma that lack MYCN [GeneID=4613] amplification. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.35E-04 1.00E+00 6.11E-03 6.05E-02 14 46 "APBA2,SPTBN4,FUBP1,CACNA1G,HAP1,CNR1,GPR85,TMOD2,ING3,PLPPR3,BTBD3,CAMTA1,ST7,ST8SIA2" Coexpression 21205295-TableS5 Mouse Viral_Buonomo11_202genes GeneSigDB 3.35E-04 1.00E+00 6.11E-03 6.05E-02 29 134 "PROM1,WASF1,CBFA2T2,CDC25B,CHGB,CRMP1,CRYM,DMD,ERBB2,SMC2,TRIM16,TPPP3,MTHFD2,DBF4,PSIP1,FAM107A,HLF,ACOT7,INSM1,MEST,NOVA1,PCSK1,PCSK5,RBBP8,RTN1,STXBP1,SYT1,USP1,SLC38A1" Coexpression 19808870-ST3 Human Breast_Speers09_24genes GeneSigDB 3.37E-04 1.00E+00 6.11E-03 6.05E-02 9 22 "NME5,DDR1,DCLK1,FGFR1,FGFR3,NBEA,STK32B,SGK3,MAP3K12" Coexpression 18818702-SuppTable2 Human Leukemia_Murati09_1686genes GeneSigDB 3.42E-04 1.00E+00 6.11E-03 6.05E-02 160 1108 "NDRG3,OSBPL8,AK2,ALCAM,PKP4,APBA2,FAM131A,CASK,LINC00173,NCOA1,ATP2A2,GPR146,PROM1,SCAPER,JAZF1,GYG2,THSD7A,CCNH,CD86,LRBA,DIS3L,B4GALT6,RAB33A,CLCN3,ARMC8,SMARCAL1,ZNF521,CSF2RA,OSBPL3,KIAA0040,PNPLA8,TCAF1,TBC1D5,DAPK1,GIT2,MYEF2,ELMO1,C2CD2L,POM121,MTX3,CPEB2,DOCK2,SLC12A6,DPH1,MBNL2,PLXNC1,TNK2,MFSD10,RASGRP2,ERCC2,IGSF6,GMPR2,FAM198B,TAOK3,CEP78,SEC23B,IP6K2,SYNCRIP,FOXO3,EVL,ZBED3,TPK1,ATP6V1H,SARAF,TRAF3IP2,IQGAP2,GCNT2,NFU1,ADAM28,MALT1,GPT2,ADGRA3,PLPP7,GRIN2D,ATE1,ZNF496,AP4S1,PSIP1,GUCY1A1,SMAP1,IRF8,IL6ST,METTL21A,IPO5,KTN1,TTYH2,PAXBP1,LMO2,MAN2A2,MATK,MBNL1,MBP,MYO5A,MYO7A,BEX5,P2RX7,PDE4B,GNG2,PFKFB3,SNX10,ZFYVE21,MTRF1L,PLXNB1,TRHDE,POLG,PPP3CC,MAPK3,PRPSAP2,TMEM104,CNTLN,MARCH1,ROGDI,BEND5,RBBP8,RET,RGS3,SLC25A36,ZNF532,RORB,RPL15,KIAA0895L,EMID1,CLIP1,SATB1,SEC14L1,MRAS,PPM1E,FBXO11,PPP4R3A,SEPHS1,CCDC88A,GKAP1,SMARCA4,IFT122,SNCA,KIF13A,LMBRD1,SAMSN1,ERBIN,CEP68,STX1A,PLCB1,SYPL1,CAMTA1,DNMBP,MGRN1,TCEA1,NSD1,ITGB3BP,SLC44A1,TRIO,TRPM2,CLDND1,ATP6V0E2,POLR3H,SPIRE1,MARCH8,MSRB3,TTC7A,AAAS" Coexpression M4308 "Genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.43E-04 1.00E+00 6.11E-03 6.05E-02 70 418 "SYN3,APBB2,APOC2,BARD1,KSR1,SYNJ2,CACNA1G,CACNA1A,CCK,SLC16A4,CDO1,B4GALT6,LHX2,CNN3,CABP1,NCOR2,CLIP3,CSF1,ARHGEF4,DAPK1,GIT2,RGS17,SRPK3,SIRPB1,ZMYND10,FGFR3,SCARA3,CAMKK2,KHDRBS3,SRCAP,ADAM28,HPGDS,GPER1,AP4S1,ITGA7,MGAT3,MX1,NEFH,NNAT,NPTX1,NPTX2,PAX6,PCDHGC3,PFKFB4,PSAT1,SAMD9,PTX3,SUSD4,KLHL11,MEG3,SALL1,MRAS,SLC6A11,SLC9A5,SLC12A4,SNAP25,CLSTN2,NXT2,HIF3A,HEY1,NR2E1,RPRM,FAM155A,UCHL1,LMF1,WNT7A,MKRN3,FAM182B,NETO2,JPH3" Coexpression M5919 Genes up-regulated by activation of hedgehog signaling. MSigDB H: Hallmark Gene Sets (v6.0) 3.46E-04 1.00E+00 6.11E-03 6.05E-02 12 36 "ACHE,NRP2,CNTFR,CRMP1,DPYSL2,L1CAM,NF1,NRCAM,PTCH1,RTN1,HEY1,VLDLR" Coexpression M1733 Cluster P3 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.48E-04 1.00E+00 6.11E-03 6.05E-02 33 160 "ZNF608,SORCS2,CC2D2A,PKP4,ATP6V0A1,BAIAP3,CAMK2B,AKAP7,CREM,CYBB,HDAC9,SPOCK2,ARMCX4,RHOBTB1,OGA,GPD2,GPR34,KAT7,FRMD5,MATK,MATN2,MBP,PPM1L,PTPN13,CLIP1,PEAR1,TRA2B,DZIP1,ST8SIA1,FAM81A,SP4,SAMSN1,ACTR3B" Coexpression M2928 Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Y). MSigDB C7: Immunologic Signatures (v6.0) 3.50E-04 1.00E+00 6.11E-03 6.05E-02 28 128 "ACTN1,ADCY6,ADRA1B,SFMBT2,ZBTB10,RGS9,CNN3,LRIG1,GPSM1,HDAC9,CHST15,IQCG,EVL,STON1,GUCY1A1,BACH2,MATN2,PKD1,SLC25A23,EML5,SATB1,ST6GAL1,DZIP1,ST8SIA1,CCDC88A,TCF4,SLC44A1,TRIO" Coexpression M4001 "Genes down-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.54E-04 1.00E+00 6.11E-03 6.05E-02 18 68 "ADORA1,SPARCL1,PPFIA4,ARHGEF6,SPOCK2,EDN3,EDNRA,MSTN,KCNH2,NEFM,PDE4D,LRRN3,PKIA,RADX,SOX11,COBL,TCF4,REEP1" Coexpression 18081427-TableS8 Mouse Breast_Crawford07_981genes GeneSigDB 3.58E-04 1.00E+00 6.11E-03 6.05E-02 104 673 "ACADM,ACTN1,FMNL2,RNF157,MTA3,TXNDC16,C1QTNF1,CASK,ZBTB10,ALDH7A1,DOCK11,MPDZ,BCL7A,GPR146,BMP7,ST3GAL5,SCAPER,DDR1,NFS1,ARHGEF25,AP4M1,LARGE1,MAGI1,CCPG1,FOXN3,B4GALT6,LHX2,ARHGEF6,CNR1,FAM149A,COL4A5,CRY2,DCAF8,AIF1L,DLX1,DMD,CD99L2,NR1D2,CDON,WDPCP,FRY,OPTN,SLC43A2,SPEG,TBC1D16,FHL1,PCYOX1,EVL,NBEA,USP21,ST6GALNAC3,STAU2,ERAP1,INPP5K,GHR,GLUL,PADI2,MAN1B1,BACH2,SYNPO,IDH3B,GATD1,LAMP2,MEF2C,SAMD5,MYO6,NME4,ETFRF1,PDE4B,PDE4D,PMP22,EXOSC10,RETREG2,SEPT4,TATDN3,CNNM2,ANKHD1,PTPRG,SLC25A48,CCDC82,MAPK12,SMARCC2,RCOR3,IFT122,SNRPN,PDZRN3,GLT8D1,IQSEC2,ST5,ADHFE1,SULF2,PLCB1,EXOC7,TBL1X,LRRC8A,TNS1,TPM2,RGMB,NR2C2,UBE2H,VLDLR,AGMO,ADAMTS9,FBXO36" Coexpression M8264 Genes up-regulated in B lymphocytes stimulated by anti-IgM: 3h versus 16h. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "DGCR6,CCDC85A,PCDH10,AMPD2,ARRB2,STK33,ATP6V0A1,SRSF11,OPTN,EBI3,MBNL2,TMEM35A,ADGRV1,POLK,SDCBP2,RAB40B,GNAL,BVES,GUCY1B1,HNF4G,SOWAHA,KTN1,MAP4,ADAM22,SFR1,PDE1C,ZNF655,CNNM2,MSANTD2,SATB1,GALNT10,HSPA4L,RCOR3,ZC3H13,NEK4,ARC,SIRT1,TMPO,PDIA2" Coexpression M8054 Genes down-regulated in macrophages: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "RALGAPA1,TMCC3,DOCK11,SYNJ1,LY86,TBPL1,CST3,DZIP3,APPL1,HDAC9,GAPVD1,WDR20,DMTF1,SNX29,CALCRL,EXTL2,EYA1,FAM198B,PTK2B,PDLIM5,RAPGEF6,GPR34,LYRM9,PLEC,SH3KBP1,MTMR10,PTPRO,OXR1,CPEB3,SLA,SULF2,DNAJC9,TCF12,ITGB3BP,SMUG1,RUNDC3B,ZFAND5,ITM2C,JMJD1C" Coexpression M5484 Genes up-regulated in comparison of dendritic cells (DC) versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ASPHD1,ALCAM,ARNTL,BID,SCARB1,SOCS6,ARHGAP22,EPS15L1,TPP1,ABCG2,CST3,SEC14L5,ARMCX1,FAM198B,CHST15,SEC23B,ATP6V1H,SESN1,GPD1,LILRA2,GPER1,LMO2,MATK,MITF,PCSK5,PILRA,FA2H,PTK2,PTX3,MRAS,WDR37,TMCC1,SST,MTCL1,TAL1,TNS1,TRIO,FAM13C,NLRP3" Coexpression M9542 Genes up-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABCF1,AK2,STOML1,IPCEF1,GAPVD1,MYEF2,EGR3,EIF1,EMX2,RRAGB,NRN1,KAT8,AMOTL2,FHL1,SESN1,KIT,LSS,AFDN,MX1,NBL1,ING3,LRRN3,PIGG,TRIM68,YY1AP1,FBXW7,S100B,SMPD3,KBTBD4,POGZ,TTBK2,KANK1,STXBP1,DICER1,CHST8,ZMAT3,LAT2,EVI5,ITM2C" Coexpression M8488 Genes up-regulated in mock treatment during adoptive transfer therapy of B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,ADORA2A,CARNS1,BCAS1,CCAR2,SLC4A4,N4BP2L1,SCAPER,ZNF445,PCYT1B,AKAP6,SNPH,DCAF8,KCTD8,NCALD,SIRPB1,CHL1,CLASRP,DISP2,DBNL,SERPINI1,SNX10,RANBP3L,PTCH1,EML5,RGS12,SETD5,STK32B,RTN1,IZUMO4,SUPT5H,TMEM150C,TPCN2,ARHGAP9,TNS1,NPL,DCBLD1,SLC38A1,CPNE4" Coexpression M3409 Genes up-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 6 h after the stimulation. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABHD6,NDRG3,AMPD2,KCNAB2,MTMR3,LDLRAD4,CLCN3,MYL6B,LY86,PICK1,COX4I1,AATK,SPATA2,ECM2,LRRC17,BAIAP2,NBEA,SESN1,ITPKB,MEST,MYO7A,NINJ2,OGG1,PCDH8,REV3L,KLHL11,SLC25A36,RXRA,SATB1,SLA,PREX2,SNCA,ARHGAP26,CEP68,DNMBP,SATB2,ZMAT3,TMPO,ATP6V0E2" Coexpression M7518 Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ZNF608,APBB2,MYOM1,ARHGEF7,RCBTB2,AKAP7,ABCG1,CSNK1G3,PITPNC1,SEMA3D,FRY,ARMCX1,FOXO3,SESN1,PARD3B,BACH2,HLF,CELF5,LRRCC1,MAP4,PKD1,RETREG1,TRIM68,MEG3,PEAR1,ANKRD6,SLC12A2,EPC1,TMCC1,FNBP1,CDK19,CEP68,TCF4,STXBP4,TSC1,TTC3,VLDLR,ZIC1,PHTF2" Coexpression M6983 Genes down-regulated in macrophages in response to LPS: naïve versus tolerant. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "RNF150,DYNLL1,LDLRAD4,CD86,LRBA,IPCEF1,HDAC9,SEMA3D,MBNL2,SLC43A2,VPS26C,TLR7,ACSL4,PRMT5,BAIAP2,CHL1,STARD3,LRRC75A,IRF8,IL12A,MIA2,POC1B,PRTG,PURG,PPP3CC,CYBC1,SNRK,TTC13,ATP8B4,SHMT2,CABCOCO1,SAMSN1,DNAJC9,PIK3R5,TRIO,TRPS1,WIPF1,EVI5,FRMD6" Coexpression M7489 Genes up-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "NDRG3,ADCY6,HACE1,OSBPL8,AMPD3,EPB41L5,DPY19L3,CBFA2T2,OSBPL3,PITPNC1,YAF2,PLXNC1,EPB41,SH3YL1,SCML2,GORAB,MED12L,FHL1,NBEA,GHR,RAB40B,GRB10,SYTL4,GPR155,PPM1L,MYCN,EPDR1,PTK2,ZIK1,CPEB4,ZBTB43,TROVE2,SEPT8,FRYL,SIK3,ZMAT3,BEX4,CCDC136,SPIRE1" Coexpression M4434 Genes up-regulated in comparison of naive B cells versus memory IgM B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "PARG,MARCH3,ATP6V0A1,BCL7A,DDR1,USP2,LARGE1,SLC4A8,EXOG,EDNRA,HEYL,TENM1,CORO2B,RASL10A,GABBR1,SYT17,SESN1,GPR12,LMO2,MMP17,PCDH9,PDE1B,ABCB1,RETREG1,RASGRF1,RADX,SATB1,HKDC1,ZHX3,CDK19,EXOC7,DNMBP,SZT2,TIMP4,CA14,SSBP2,SLC30A4,PRDM10,JPH3" Coexpression M9381 Genes up-regulated in follicular B cells versus marginal zone B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "MAP4K3,ATP2B2,AZGP1,DDR1,CACNA2D1,MS4A7,IGLON5,AKAP7,CNRIP1,PPP6R2,USP6NL,BOC,NCALD,TMEM132C,PRAM1,FOXO3,MTHFD2,CPLX1,NEU3,GRIN2D,GRM2,FRMD5,GPR155,MAP6,MEF2C,NCF2,OPA1,PRIMA1,C12orf49,SCN2B,CNKSR2,HECW1,SSTR2,HIF3A,P2RY12,SLC30A4,EMSY,SEMA3B,IFT88" Coexpression M8532 Genes up-regulated in macrophages: resting differentiated versus MYC [GeneID=4609] inhibited. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ADRB2,TXNDC16,ALCAM,BTK,HIP1R,LDB2,CD38,CPNE6,CNN3,MYADM,EBF1,EBI3,EPB41L2,RASGRP2,FCGRT,GABRA3,GAD1,GCK,GRIN2D,GSN,IRF8,LAMP2,MEF2C,MYO5A,MYO7A,PLTP,ZDHHC14,ZNF532,DNAJC9,SYPL1,TCF4,KIAA0930,NSD1,LRRC8A,C9orf85,LAT2,SLC30A4,URM1,PHTF2" Coexpression M9535 Genes down-regulated in skin: uninfected versus S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "NDRG3,AP2A2,GAS7,APOC1,NRP2,SCARB1,UBE2L6,NSL1,OSBPL3,CST3,TBC1D5,RHOBTB1,ABCC5,ANKRD46,EPB41L2,COQ7,IGSF6,CDKL3,TBC1D16,ZNF589,FECH,IQCG,FOLR2,GATM,IGF1,MAT2A,P2RY13,PCSK5,PIK3R1,PILRA,CYBC1,QDPR,AP1AR,DGLUCY,ST6GAL1,SLA,SPP1,UBE3B,SMIM8" Coexpression M3227 Genes down-regulated in regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "AP2A1,ADGRF5,TRMT9B,FAM131A,PRX,KIF1A,RGS9,RAB29,VXN,LY86,GSDME,ABCC5,FRY,LRRC17,ZMYND10,DENND2A,CPLX1,KCNMB4,GP1BB,NXPH3,HP,SCIN,IL12A,INPP5B,MGAT3,FXYD7,SH3KBP1,PPP2R2B,NKAIN4,SLC26A11,CRTAC1,MAP6D1,RTN1,PHLDB1,PHF24,NSD1,BEX4,TFIP11,NHSL1" Coexpression M9293 Genes up-regulated in Lung dendritic cell from untreated wildtype mice versus Lung dendritic cell from Ad5 T424A hexon infection wildtype mice. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "PKP4,ZNF583,CFAP410,AKAP6,ABCG1,PPP1R16B,DGKG,DNAL1,RAB39B,REEP2,CORO2B,C2orf88,GAA,USP19,GNAO1,GRIK4,ITGA7,JAK2,MYH3,NFE2L2,NTRK3,SETD4,TMIE,MTMR10,CARF,CNKSR2,DZIP1,KDM4D,KIF13A,USP33,TK2,CDK20,ZNF346,TSC1,CLHC1,UBE3A,TOM1L2,CLIP2,MEIS3" Coexpression M4880 Genes up-regulated in comparison of neutrophils versus monocyte macrophages. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACADM,MTUS1,MARCH4,TRMT9B,CDK13,BBS2,CNR1,MAGED1,IPCEF1,SIPA1L1,ARHGEF4,ZBTB24,YAF2,ING4,FCGR3A,FOXO3,DCTN2,FAM120B,SYT17,ARFIP1,AGBL5,LMO2,MBP,NFE2L2,SMOX,PDZRN4,STRN3,MAPK3,RAD51D,RAP1GDS1,ZDHHC4,ZFHX4,SHC4,SIRT2,ATF7IP,TACC1,EXOC7,MGAT5B,LGI4" Coexpression M8038 Genes up-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "OSBPL8,MARCH3,RAB29,CD38,RAB33A,CLCN3,RCHY1,AHCTF1,ARHGEF4,ZFYVE16,GOLGA7,DENND4A,FLT1,ZNF274,MALT1,PRRC2B,GRB10,IL6ST,MBD1,PLEC,PPM1B,PPP2R5E,PPP3CA,CYBC1,GTDC1,MAP6D1,S100B,SMARCD3,DOP1A,PJA1,MCF2L,TBL1X,PUM2,UBTF,ZNF24,PCBP4,MPPE1,UBE3B,JMJD1C" Coexpression M5821 Genes up-regulated in comparison of naive CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACADM,CLK4,ADD1,BRAP,ADRB2,LRWD1,CNN3,FAM107B,FARSB,ABCC5,MRPL37,JKAMP,GABBR1,SRCAP,SESN1,GGT5,TXNL4A,RNPS1,GSN,GSTT2,ELOVL5,MAT2A,MBP,GIT1,PKD1,PRKCB,CYBC1,EML5,RAD17,CLIP1,SATB1,GALNT10,SGK1,FAM102A,ST6GAL1,INTS9,SS18,TBCEL,MTCH1" Coexpression M4341 Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "SEMA7A,CCDC146,EPB41L5,ARRB2,CDH2,IGLON5,AKAP5,CRY2,CRYM,LRIG1,ARHGEF10,HDAC4,ARMCX2,CERCAM,RAB9B,F8,FCGR1A,AKAP3,CHL1,SRCAP,HTATSF1,GUCY1B1,CDH20,KCNH2,AFF1,ZNF827,PKD1,PILRA,DRAM2,PPP2R2C,MAPK12,FAM102A,LARP4,ARHGEF9,MCF2L,FRYL,ZFP37,STOX2,NETO1" Coexpression M7437 Genes up-regulated in CD4 [GeneID=920] T cells: TGF beta versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "BRAP,AP2A2,LGR5,SLC4A4,N4BP2L1,HCN2,VXN,CCNT1,RGN,CBFA2T2,DLGAP1,MAP4K4,AIF1L,DCTN1,DNAH9,DUSP9,ST6GALNAC3,FUT9,GNAL,GRIN2D,MSL1,TTYH2,PALM,KANSL1,SLC26A11,KHDRBS2,SCN7A,ZFP30,LIMS2,NAPB,LGI3,KIF13A,SEPT3,FAM189A1,RGMB,PROCA1,DHX33,ADAMTSL3,ST8SIA2" Coexpression M6715 Genes down-regulated in endothelial cells: untreated versus IFNG [GeneID=3459] and B. burgdoferi. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "VAT1L,MARK4,KIF1A,CARMIL3,CABP7,C4orf33,CRYBB1,CLIP3,FAM131B,KIF26A,SPOCK2,TIAM2,CHRDL1,DNM1,PDCD6IP,LRRC17,SDCBP2,GAA,SRRM4,GPR75,FAM222A,HNF4G,LRRCC1,MYO9A,PDE1C,NECAB2,PRODH,PRPH,MTMR10,RXRA,FRMPD1,SLC2A5,SOX3,PEG10,SEPT3,CLEC2L,PLPPR2,ZFP41,NETO1" Coexpression M6477 Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (3h). MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ZNF608,MTUS1,PI16,APOC1,MARCH3,STX16,N4BP2L1,ADAM23,FOXN3,ENTPD4,TIAM2,FAM107B,SLC12A6,IGSF6,ZMAT1,GCNT2,TUBGCP4,GFRA2,ELOVL5,IL6R,INSM1,KCNJ16,L1CAM,PAXBP1,BLOC1S2,ADAM22,PRKCB,ROGDI,RGS12,KCNIP3,RYR3,SEMA6D,RASA3,ST8SIA1,ATF7IP,SAMSN1,PUM2,NR2C2,JMJD1C" Coexpression M9763 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "AP2A2,SPOP,CARNS1,TNRC6C,CDC14B,BACH1,ARHGEF1,C1orf52,CNN3,COL9A3,ZFP28,CLOCK,ERC2,GPRASP1,IP6K1,TOM1,RASGRP1,FCGRT,FGF13,WASHC2A,MITF,PDE1B,SERPINI1,PLEC,POLG,RIPOR1,RAP1GDS1,TMLHE,USP33,KDM3A,ITPRID2,TTBK2,FRYL,TRIO,TBC1D15,KCNAB1,MPPE1,RNF146,SENP7" Coexpression M9751 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ALCAM,NRP2,IL33,CACNA1B,ENTPD6,OSBPL3,ELMSAN1,SACS,RAB39B,CDON,EGR3,CERCAM,FGF12,SEMA4D,GAA,MALT1,HPGDS,GNG4,ATOH8,TOX2,NXPH3,RBPJ,IL6ST,RETREG1,PMP22,RASGEF1B,PTPRN,RGS3,RPS6KA2,SARS,PREX2,SPP1,ITPRID2,FLRT2,LAT2,AMZ1,FSTL5,PRDM8,ADAMTS10" Coexpression M3675 Genes up-regulated in comparison of T effector cells from uninfected mice versus T effector cells from mice infected with S. mansoni. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,ADD1,ADRB2,AP2A2,SORCS2,PCDH10,AMPD3,FGD2,SFMBT2,NUMB,CAST,CHRNA4,CNN3,RIPOR2,SRPK3,TLR7,SEC24B,PADI2,MEF2C,MAPKAP1,PPP3CA,PRPSAP2,RIPOR1,ERI2,MCMBP,LRRK2,GALNT10,SCAF8,MYO18A,LMBRD1,MYCBP2,KDM4C,STX1A,KLHL7,METTL3,UBTF,SPHK2,ZNF142,FAM13C" Coexpression M9285 Genes down-regulated in CD8 T cells 6 days after immunization: control versus IL2 [GeneID=3558] treatment. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,ZNF608,SEMA7A,EPB41L5,DPY19L3,SYNJ2,LDLRAD4,DDR1,MAP4K4,AKAP12,LRIG1,USP6NL,GPRASP1,SPOCK2,RASGRP1,EGR3,ZMAT1,TOX2,SYNPO,AGFG1,IL6ST,MATK,NFIX,NUCB2,P2RX7,RETREG1,PLCL1,PPM1B,TMLHE,PEAR1,ST6GAL1,ANKRD6,FAM81A,KIF13A,CABCOCO1,TIAM1,TTC3,ZNF24,TUBA1A" Coexpression M5786 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 1 month later. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "OSBPL1A,SEMA6A,BMPR1B,DST,SLC25A14,CCNT1,CBFA2T2,EPS15L1,COX4I1,CLOCK,SLITRK5,ARMCX4,RHOBTB1,SUGP2,EIF5,ING4,C3orf18,RCAN2,RABEPK,PIPOX,DCTN2,PRELID3A,GFER,GUCY1A1,GUCY1B1,HSPA1L,KCNN3,SMAD1,NRCAM,PDPK1,CCSER2,TMEM104,TUG1,C1orf54,RPL15,ATAT1,PBLD,TROVE2,TRIM2" Coexpression M6415 Genes up-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACADM,ACTN1,NDRG2,BEND6,ASGR1,ZBTB10,TMEM108,ATP1B3,RNF182,LDLRAD4,USP2,ABCG2,CSNK1E,SPOCK2,LYPD1,EIF1,EXTL2,PPP1R1B,SARAF,GGT7,GLUL,GUCY1A1,RASSF8,SKOR1,FITM2,PRODH,PTK2,SUSD4,TMLHE,MCMBP,SATB1,BTBD7,ATF7IP,STX1A,PJA1,KIAA0930,TSC1,FRMD6,SENP7" Coexpression M8975 Genes up-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "TMEFF1,ARRB2,RGS9,PTBP2,BAG4,SEC14L5,GIT2,TIAM2,FBXL5,DCLK2,STON1,IL6ST,MBNL1,MN1,NEFM,PDE3A,GPR173,PPARA,PRODH,C1orf109,ACSM5,ACSS3,RASGRF1,CCDC25,NUBPL,PDZRN3,ZHX3,VPS13A,SYT5,KLHL4,DOCK9,PIK3R5,UBTF,XRCC4,ZNF195,ZNF225,EVI5,PLSCR4,FZD3" Coexpression M5683 Genes up-regulated in comparsion of ActCD8 versus ActTreg (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "GAS7,STX16,BAIAP3,CABP7,CNRIP1,FBXL5,SV2B,AASDH,IRAK4,NCALD,RACK1,ST3GAL6,FCGRT,GTF2IRD2,EVL,SARAF,GABBR1,B4GALNT1,ACSS1,MALT1,P2RY13,IDNK,PDE4B,PDPK1,ABCB1,NKAIN4,SNRK,EML5,TTC13,TMEM231,SATB1,ZFP30,ARHGAP26,FRYL,NACC2,PRRT1,TTC3,UBE2H,MPPE1" Coexpression M9171 Genes up-regulated in CD4 [GeneID=920] T conv: over-expressing IKZF4 and LEF1 [GeneID=64375;52276] versus control. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ADD1,ZNF608,WDR35,ARHGAP20,ARNTL,MTMR3,CFAP410,QKI,ABCG1,USP6NL,GPRASP1,DAPK1,IP6K1,YAF2,EPB41L2,STX2,ARMCX1,KIAA1958,STON1,GRIK5,BACH2,CELF5,ICA1,SCIN,IL6R,LIG4,POC1B,AFF1,RTL5,NUCB2,PPM1B,GTDC1,KIF7,SPTAN1,SPTB,SULF2,TIAM1,WBP2,PHTF2" Coexpression M4677 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,KLHL32,RNF157,MTA3,C1QTNF3,ZSCAN18,NUMB,ZNF582,FOXN3,ARMCX2,MRNIP,C8orf37,NBEA,RAB30,ADGRA3,PRRC2B,LINC01550,HSF2,ITPKB,MYO9A,ZC3H12B,IDNK,FAM216A,PLCL1,DRAM2,VPS13C,PTK2,ZNF844,RMI1,CNKSR2,KDM4C,PBLD,BHLHB9,NR2C2,TSC1,SSBP2,PRDM10,FAM13C,LAS1L" Coexpression M9272 Genes down-regulated in spleen B lymphocytes versus bone marrow plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "RNF157,ADORA2A,SEMA7A,EPB41L5,BAIAP3,CDC25B,CRMP1,CSF2RA,OSBPL3,MYADM,SPOCK2,RAB39B,PLXNC1,C8orf37,ST3GAL6,GAA,GPR34,TOX2,CAMK2N2,GPR155,MATK,CHIC1,ABCB1,PLXNB1,POU6F1,PPP3CC,SLC26A11,PTPN13,PID1,SALL1,MAPK12,SCN8A,PEAR1,FAM214B,ARHGAP26,GPRIN3,ERCC6L2,ITM2C,ST8SIA2" Coexpression M8081 Genes down-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABR,TBC1D14,PKP4,GAS7,MADD,BBS2,BAG4,PREPL,MYADM,IP6K1,APOPT1,TRAF3IP2,B4GALNT1,IQGAP2,SEPT9,ACSS1,GLUL,PARD3B,SPACA9,SLC2A6,MSL1,IL6ST,NCOA7,GIT1,MYO7A,NFIX,PIK3R1,CCSER2,PMP22,SH3KBP1,DGLUCY,HSPA4L,ZSWIM8,SYNE2,MGRN1,ZMAT3,PIK3R5,ZNF189,SLC38A1" Coexpression M8632 "Genes up-regulated in bone marrow-derived dendritic cells treated with 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose." MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABCD2,APC,GPR146,CAMK2G,CAST,RCBTB2,ANKRD44,AATK,IPCEF1,GALNT9,TMCC2,KAT8,FOXO3,SESN1,CACFD1,KIF5A,STXBP5,L1CAM,GPR155,MAN2A2,TM6SF1,MEF2C,RTL5,RETREG1,PURG,MINDY2,RNASEL,TMLHE,PCMTD2,ST6GAL1,SLC8A1,TET1,TCF12,ARHGAP9,THRA,TLR4,R3HDM1,ZNF708,ADAMTS10" Coexpression M4478 Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "LTBP4,BIN1,ZSCAN18,LRBA,CDC25B,PLEKHB1,RAB33A,MAGED1,LRIG1,FAM169A,GPRASP1,SPOCK2,ENO2,SH3YL1,EVL,SESN1,ZNF276,BACH2,NELL2,NUCB2,CCSER2,RETREG1,LRRN3,PKIA,CCDC25,SATB1,FAM102A,KBTBD4,KDM3A,MPRIP,CEP68,SYNE2,DNAJC9,PJA1,DOCK9,AKTIP,KAT6B,ATP6V0E2,SLC38A1" Coexpression M9354 Genes up-regulated in heterozygous knockout of BCL6 [GeneID=604]: follicular versus marginal zone source. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "AS3MT,AMPD3,DOCK11,AP1M1,SPAG9,ZNF445,B4GALT6,TPP1,CSNK1E,RIPOR2,ALKBH8,WDPCP,SLC43A2,CDKL3,RACK1,FLYWCH1,TMEM175,FAM120B,INPP5K,ACSS1,DBF4,GSN,FICD,L1CAM,ZFYVE27,ADAM22,MAPK7,RTN1,DGLUCY,SLA,MYCBP2,ARHGAP26,SUPT5H,PDLIM2,SZT2,ARHGAP9,CELF4,EML6,TTC7A" Coexpression M4097 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABR,APBB2,MARK4,N4BP2L1,MTMR7,C1orf52,CSF2RA,CYBB,GUCD1,PARD6A,ASB3,STARD3NL,SPEG,FER,PCYOX1,ATP2C1,GALC,NEU3,TNRC6A,STARD3,IRF8,MSL1,MBP,SNX10,SMOX,DRAM2,RPE,MCMBP,FAM192A,SLC2A5,CDK5RAP2,STXBP1,ARC,FBXW11,ZEB1,CDK20,WBP2,HPS4,SNX14" Coexpression M6310 Genes down-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 3h. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "TBC1D14,TMEFF1,CA12,CAPN3,CHGB,RBM39,CRMP1,RNF14,GPRASP1,ENO2,MED12L,FGF12,SPECC1,GABRB3,TRAF3IP2,INPP5K,TUBGCP4,PPARGC1A,CHIC1,AFF1,COMMD5,NEK1,NNAT,SETD4,SERPINI1,PKIA,MAPK10,ELOVL2,PTK2,PTX3,SCAF8,FHOD3,DICER1,SLC44A1,BEX4,SLC35A4,ZNF23,ST7,JPH3" Coexpression M9163 Genes down-regulated in CD4 T conv over-expressing XBP1 [GeneID=7494] versus XBP1 and FOX3P [GeneID=7494;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,ADCY6,TMCC3,INTS2,ARHGAP20,RASL11B,ALDH7A1,ZMYM4,ABCG2,HOMER3,MAGED1,GPSM1,ARMCX2,NYAP1,ARMCX1,CEP78,UBE2E3,B4GALNT1,KIAA1841,KDM2B,GSN,BACH2,NIM1K,JAK2,KIFC3,KIT,WBP1L,RGS12,GSTCD,ATXN2,TNFRSF19,ZFP30,CCDC88A,TET1,POGZ,ARHGEF9,TTC3,INTS3,NETO2" Coexpression M5773 Genes down-regulated in dendritic cells (DC) from spleen versus those from intestine. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "TMCC3,FAM135A,AMPH,MYOM1,BARD1,CLTB,FAM189A2,SMARCAL1,IST1,DNAL1,DNAJB6,DNM1L,MRVI1,FCGR1A,BAIAP2,ZMYND15,TMEM107,FYB1,CHL1,GALC,LYVE1,NCOA7,LYPLAL1,SCAMP5,NPY,LRP12,NUDT11,ALG9,KCNIP3,MRAS,CLASP2,PHLDB1,KLHL7,SLC37A2,TCF12,TPM2,P2RY12,AGMO,PRDM8" Coexpression M5705 Genes down-regulated in comparsion of sfActCD4TGF versus ActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "MTUS1,CARNS1,MTMR3,CAST,MAP4K4,LRIG1,ARHGEF10,IPCEF1,ARHGEF4,DOCK4,RIPOR2,MAML1,PITPNC1,CDON,KMT5B,CALCRL,GPHN,SLC43A2,TBC1D16,FGF13,ACSS1,TUBGCP4,SESN1,PRRC2B,ADAMTS6,IL6ST,MBP,NFIX,NTRK3,NUCB2,SMOX,CEP97,CHD9,TCF4,KIAA0930,SLC44A1,PDIA2,IFT88,SENP7" Coexpression M9386 Genes up-regulated in day 40 memory B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "PLEKHH1,ANK2,BCAS1,IGDCC4,MPDZ,RGS9,TBRG4,SLIT2,C2CD2,OSBPL3,CNTNAP2,PLCXD3,DTNB,EDN3,PLXNC1,POLR1B,USP21,GABRG1,STARD3,NOVA1,CNTN3,GPSM2,FAM216A,WDR25,RAD17,FIGN,ROBO2,ZSCAN29,ADHFE1,TPCN2,TNS1,PPIL6,TTC3,EIF4ENIF1,ZIC1,CADM2,STOX2,FXR1,SOCS4" Coexpression M6618 Genes up-regulated in bone marrow-derived macrophages with IL6 [GeneID=3569] knockout and 45 min of stimulation by: LPS versus IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABHD6,PPFIA4,SPAG9,CCPG1,QKI,MAGED1,DOCK4,MYADM,ARHGAP24,NR1D2,ETV1,KATNAL1,EZH1,FOXO3,ZBED3,USP21,GHDC,HMGCL,IL6R,PTOV1,MXI1,CNOT4,STRN3,PRKAB2,MAPK3,PRPSAP2,BCAS3,TMLHE,SEC14L1,CHD9,FAM219A,FNBP1,ANKRD28,SMG6,MTMR14,ZKSCAN5,VPS35L,PLSCR4,FRMD6" Coexpression M5434 Genes up-regulated in comparison of mast cells versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ABHD6,PKP4,ARRB1,CACNA2D2,CLTC,AKAP12,OSBPL3,IPCEF1,DAPK1,RHOBTB1,RCAN1,EXTL2,TAOK3,ST3GAL6,FOXO3,FYN,GLUL,ADGRA3,GRB10,GSN,HNMT,HP,TREM2,OLA1,PIK3R1,SMIM7,LRP12,FRMPD1,SMARCD3,SPP1,ITPRID2,SST,ELOVL4,STX1A,SIN3B,TP53BP2,SLC30A4,ST7,RNF146" Coexpression M9035 Genes up-regulated in macrophages with heterozygous knockout of HDAC3 [GeneID=8841]: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ACTN1,SORCS2,PITPNM2,CBFA2T2,CACNA2D2,CLOCK,CRY2,IST1,IP6K1,ARMCX4,NR1D2,PLEKHA1,CALCRL,DNAJC27,CD320,SARAF,BACH2,ITPKB,SMAD1,AFF1,PIK3C2A,RETREG1,KLK6,PTK2,EML5,MSANTD2,DZIP1,ZFP1,KDM3A,STAU1,PHLDB1,STX1A,ZFP90,AMACR,UBE2H,RNF103,PPP1R3F,DPF3,RNF146" Coexpression M5390 Genes down-regulated in comparison of dendritic cells (DC) stimulatd with LPS (TLR4 agonist) at 48 h versus macrophages stimulated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "ADRB2,AMPH,NUMB,HCN2,PRC1,LRBA,TPP1,VCAN,ERC2,CYBB,DUSP9,SEZ6L2,EDN1,SRPK3,FCGR1A,ERGIC3,TRAF3IP2,SEPT9,GCNT2,VSIG4,KCNJ5,LSS,MARK1,MSR1,NDP,OCRL,P2RX7,PFKFB3,KCTD15,ZNF426,RAP1GDS1,GAL3ST4,MCMBP,SPP1,SSTR2,KLHL7,SIK3,UBE2H,LAT2" Coexpression M8653 Genes up-regulated in P14 CD8+ T cells: ST2 [GeneID=6761] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "TXNDC16,FGD2,NCOA1,RASL11B,EIF4G3,DOCK11,CAMK2G,RCBTB2,SOCS6,CNOT8,ANKRD44,ABCG1,PHF14,RIPOR2,DPYSL2,PRAM1,PRKAG2,FOXO3,ANKFY1,SESN1,HMGCL,IL6R,FAM69A,L1CAM,GPR155,MAN2A2,P2RX7,PDPK1,SLC26A11,PCMTD2,RASA3,CDK19,SEPT3,PDLIM2,TCF12,ARHGAP9,HEY1,MPPE1,NHSL1" Coexpression M6774 Genes down-regulated in splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 6.11E-03 6.05E-02 39 200 "DGCR6,MTUS1,CDK13,RASL11B,ARHGEF1,SCARB1,ENTPD6,LRWD1,FOXN3,SLIT2,SEC14L5,RASSF2,IP6K1,ARMCX2,SACS,HSD17B14,MRPL37,HPCAL4,FYN,GAA,GABRG2,GATD1,ALDH1L2,NFYA,PKD1,TTC13,BEND5,REV3L,SHMT2,FHOD3,DHX30,SMARCC2,RBM34,TACC1,PCDHB7,ZNF346,REEP1,RNF103,NAV3" Coexpression M11896 Genes whose expression profile is specific to Cluster IIa of urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.64E-04 1.00E+00 6.17E-03 6.12E-02 30 141 "ALCAM,CFL2,CNN3,ARMC8,WHRN,FAM171B,CYBB,DPYSL2,RCAN1,RCAN2,ACSL4,ZMAT1,IQGAP2,GSN,PSIP1,RASSF8,TOX2,KIF2A,LIG4,LMO2,MBNL1,MYO5A,PMP22,SGK1,ST6GAL1,CDK5RAP2,STXBP1,FAM200B,TRPS1,ZFAND5" Coexpression 19168792-TableS2 Human Leukemia_Figueroa09_567genes GeneSigDB 3.68E-04 1.00E+00 6.23E-03 6.18E-02 70 419 "CCDC85A,PTCHD1,OSBPL6,C1QTNF3,SEMA6A,CDC42BPA,SPTBN4,CADPS,TTLL9,BMP7,SYNJ2,CACNA1I,CACNA1A,CACNA2D1,CBLN1,CCK,MAGI1,CHGB,GALNT9,KIF26A,PABPC5,ZNF804A,LYPD1,GRIN3A,CELSR3,ETV1,ST3GAL6,BAIAP2,CSPG5,GABRB3,GPR34,GPR37,SOX21,FRMD3,HMGCR,IRF8,GPR62,KCNN2,MAP6,MBP,NEFM,NOVA1,PCDH8,PIK3R1,TRHDE,RELN,PTPN13,RASGRF1,RET,SALL1,LRFN5,HSPA4L,TRIM67,SNAP25,PDZRN3,SOX3,SMG6,SATB2,PCDHGC5,PCDHB6,TPM1,RGMB,FLRT2,KCNK12,PCDH20,SPIRE1,ADAMTS9,WNK3,HRASLS,JPH3" Coexpression 18565887-TableA8 Human StemCell_Murat08_25genes GeneSigDB 3.69E-04 1.00E+00 6.23E-03 6.18E-02 8 18 "BBOX1,SLC25A18,DTNA,ITPKB,NDP,P2RY1,PAX6,NR2E1" Coexpression M16533 Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion and down-regulated in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.69E-04 1.00E+00 6.23E-03 6.18E-02 8 18 "CDC14B,LRBA,CNTNAP2,NOP56,IDH3B,SLC2A5,CLASP2,TBL1X" Coexpression M14601 Genes up-regulated in hepatoblastoma samples compared to normal liver tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.70E-04 1.00E+00 6.23E-03 6.18E-02 40 207 "ALCAM,LGR5,MAP4K4,MAGED1,CS,SOCS5,DZIP3,GREB1,RHOBTB1,PLXNC1,ETV1,RPS6KC1,FDFT1,SUCO,GLUL,CBX1,HMGCR,PDCD2,RELN,ACSS3,SLC25A36,ROBO1,MEG3,SEPHS1,SMARCA4,RCOR3,RBM34,PEG10,SEPT8,CEP68,TACC1,OBSL1,CBX5,R3HDM1,TSN,ZBTB38,ZNF189,MFF,MARCH8,FXR1" Coexpression M15476 Genes up-regulated in primary adipocytes compared to preadipocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.75E-04 1.00E+00 6.31E-03 6.26E-02 19 74 "MTUS1,AGT,AMT,MAP4K3,SPTBN4,ATP2B2,DGKG,ECM2,MSTN,GLUL,GPD1,KCNH2,PFKFB3,PLCD1,PLIN1,FXYD1,MASP1,DPF2,RXRA" Coexpression 18927307-tableS3 Human Colon_Allen08_382genes GeneSigDB 3.86E-04 1.00E+00 6.49E-03 6.43E-02 42 221 "USP31,ADGRF5,PKP4,CDC14B,ATP1B3,DST,CAMK2G,KRIT1,MAGI1,MAP4K4,NCOR1,ARHGEF10,ZFYVE16,ZBTB24,USP3,CDON,FARSB,YAF2,MBNL2,EIF4G2,PAN3,GPHN,DLC1,UBE2E3,DCTN2,GPR75,AP4S1,MAP2,MBNL1,MBP,MID1,PPP3CA,PTK2,PTPRG,RFX3,SETD5,TMLHE,POGZ,ANKRD28,ACTR6,TRIO,RTN4" Coexpression M6508 Genes up-regulated in monocyte-derived dendritic cells: LPS versus vehicle. MSigDB C7: Immunologic Signatures (v6.0) 3.87E-04 1.00E+00 6.50E-03 6.44E-02 38 194 "ACTN1,RNF157,ESYT2,ABCD2,PITPNM2,USP6,CD38,TBRG4,NOG,CNN3,IPCEF1,KIAA0319,KLHL3,SPOCK3,EPB41L2,BAIAP2,ZBED3,RAPGEF6,ARFIP1,USP19,BACH2,MYLK2,FXYD7,KSR2,NUCB2,ENPP2,SDK2,PRKAR1B,FITM2,SNRK,GAL3ST4,RFX2,PTGR2,SEMA6D,BTBD3,SYN2,MLST8,METTL3" Coexpression M2783 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of PCGF2 [Gene ID=7703] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 3.91E-04 1.00E+00 6.55E-03 6.50E-02 31 148 "NDRG2,GAS7,PROM1,SLC16A4,UBE2L6,CHN2,COL9A3,CREM,CLIP3,SNCAIP,TCAF1,DMD,PDLIM5,SYT17,PPARGC1A,STON1,KCNJ16,PCDH8,PDE4B,SERPINI1,PID1,C1orf54,PNMA8A,BAALC,KANSL3,DOK5,NMNAT2,PLCB1,CUX2,TRIM2,CDH22" Coexpression M9695 Genes up-regulated in DLBCL (diffuse large B-cell lymphoma) cell lines sensitive to stimulation of CD40 [GeneID=958] relative to the resistant ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.99E-04 1.00E+00 6.67E-03 6.62E-02 39 201 "KDM5D,DST,BTK,CD86,CD38,FOXN3,CLTB,MAP4K4,CREM,NCOR2,RUBCN,PARD6A,DPYSL2,EPB41L2,TUBA1B,TUBB3,NSG1,IRF8,KCNN3,MEF2C,MEIS2,MEST,SNX10,PPP3CC,PRPSAP2,NUDT11,SBF1,INTS9,PEG10,SS18,SYPL1,TACC1,PDLIM2,TCEA1,KIAA0930,SYNE1,HSPBP1,TUBB2A,VAV1" Coexpression M6764 Genes down-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.00E-04 1.00E+00 6.67E-03 6.62E-02 28 129 "HECW2,MYH7B,JAZF1,NOG,ELN,APC2,FGFR3,GABRA3,AIFM3,ADGRA3,TOX2,ZIC5,NRBP2,HS6ST3,NPTX2,SDK2,MAGEL2,PTN,KIF7,LGI3,NFASC,STXBP1,SYT5,DMXL2,CLEC2L,REEP1,CADM2,DNALI1" Coexpression 19036130-TableS1a Mouse Viral_Mendoza-Villanueva08_1830genes GeneSigDB 4.00E-04 1.00E+00 6.67E-03 6.62E-02 216 1561 "ABCF1,ACADM,AS3MT,NDRG2,GALNT16,KLHL13,SRPX,ABCD2,BBOX1,BIN1,PI16,APBB2,ARRB1,ASPA,NUMB,RASL11B,DYNLL1,ATP1A1,ALDH7A1,MYOM1,MPDZ,CFLAR,BMP7,DST,SGCE,CAPN3,CAST,CARS,RUNX1T1,PRC1,LDB2,CD86,CD38,ENTPD2,CDH2,LRRFIP1,LARGE1,CDO1,CFL2,SLIT2,LHX2,RAB28,ABCG2,LY86,CNN3,ABI3BP,CLOCK,AKAP12,GDA,CRYM,CSF1,CSF1R,PDE4DIP,CST3,CTH,CYBB,DAPK1,ARMCX4,ARMCX2,CHRDL1,DLX1,DNM1,NR1D2,DOCK2,DTNA,EBF1,FEM1B,HEYL,EIF5,PCOLCE2,ELN,CALCRL,IGSF6,EXTL2,ARMCX1,ACSL4,TUBB3,TAOK3,ST3GAL6,FCGRT,OLFM1,FGF13,FGFR3,FHL1,SCARA3,FLNC,FOLR2,SMC2,PDLIM5,FYB1,CHL1,GATM,TUBA8,CSDC2,GHR,DBF4,GLUL,HTATSF1,GNG4,GPT2,ADGRA3,GP1BB,GPD1,GPR34,GPR37,GRB10,PLPP7,GSN,COQ10A,GSTT2,SOX21,GUCY1B1,NCKAP1L,ACOT7,HNMT,IDH3A,MYLK2,IGF1,IL6ST,KIT,LAMA2,STMN1,LIFR,LMO2,LSS,ASPRV1,GPR155,MARK1,MBNL1,MBP,TM6SF1,MEF2C,AFF1,TAGLN3,MX1,MYCN,NFIX,NNAT,NPY,NOVA1,NPR2,NTRK2,NUCB2,ETFRF1,PDE4B,ENPP2,PFKFB3,PGAM2,PIK3R1,SNX10,ZFYVE21,TMEM38A,GPSM2,SMOX,FXYD1,PMP22,SCHIP1,FA2H,PPP1R1A,PPP3CA,PKIA,RELN,GDPD2,PTCH1,PTPN13,PTPRO,RBBP6,ZDHHC14,SLC25A36,RNASEL,ZFHX4,ROBO1,HUNK,MAPK12,SATB1,RASA3,SH3BGR,CPEB3,SHMT2,FHOD3,PEX26,DHX30,LIMS2,SLC11A1,SLC12A2,SLC22A4,SMARCD3,SPP1,ERC1,UNC5B,THSD1,ELOVL4,ADHFE1,PHLDB1,AGTPBP1,TCF4,SYNE1,TEK,ZFPM2,ZNF106,TIMP4,TLR4,TPM1,TPM2,SYNPO2,DCBLD1,TUBB2A,SGK3,UBE2H,VLDLR,WIPF1,P2RY12,ZIC1,NDRG4,SEMA3B,PLD4" Coexpression M19930 Genes up-regulated in B-CLL (B-cell chronic leukemia) samples expressing high levels of LPL [GeneID=4023] compared with those expressing low levels of the gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.01E-04 1.00E+00 6.67E-03 6.62E-02 17 63 "BCL7A,SGCE,AKAP12,KIAA0040,ARMCX2,ELMO1,GSDME,DMD,FRY,TLR7,DCLK2,BACH2,FAM69A,ST6GAL1,PEG10,DNMBP,FBXW11" Coexpression 20460173-ImmPortAnti-IgMvsControl Human Immune_Kong10_1790genes_ImmPort_Anti-IgMvsControl GeneSigDB 4.09E-04 1.00E+00 6.80E-03 6.74E-02 165 1152 "RALGAPA1,ABR,ADD1,ADORA2A,ALCAM,ALK,AMPD2,APOC2,LGR5,SHROOM2,MADD,CASK,RGS20,ARRB2,PCDHGB4,ATP1A3,ATP6V0A1,BARD1,BCL7A,BID,CFLAR,SGCE,CALM1,CBS,ARHGEF1,CD38,AP4M1,LRBA,ARHGEF2,CDC25B,CDH2,LRRFIP1,UBE2L6,COPB2,RCBTB2,FOXN3,PPT2,MYL6B,SULT4A1,LY86,ARHGEF6,LETMD1,COX4I1,CREM,CRY2,RNF14,CS,ARHGEF10,OSBPL3,PPP1R16B,HDAC9,DCAF8,TBC1D5,MAML1,IP6K1,ELMO1,GSDME,DPYSL2,DNAJB6,ABCC5,RASGRP1,CELSR3,EGR3,EIF4G2,EPB41,MFSD10,EPB41L2,RCAN2,RASGRP2,ERCC2,DENND4A,NCALD,EXTL2,PTK2B,TUBB3,RACK1,ST3GAL6,CHST15,ATP5PD,CSPG5,FYN,MTHFD2,GCNT2,MALT1,FERMT2,GPD2,LILRA2,GPER1,CIT,HAS2,PACSIN2,NCKAP1L,ATXN2L,ELOVL5,GABARAPL2,AGFG1,SMAP1,IRF8,IDH3A,IFI16,INPP5B,ITPKB,KCNN3,KHK,STMN1,LSS,MAN2A2,MARK3,MAT2A,AFF1,PTOV1,MX1,MXI1,SLC11A2,SETD4,OCRL,OGG1,PCDHGC3,ABCB1,PKM,PMP22,PRKCB,PRPSAP2,CNNM2,NDUFS7,PSMA6,PTCH1,RPE,SAFB,SEC14L1,SGK1,FAM102A,ST6GAL1,SLC2A5,SLC12A4,SMARCA4,LIMCH1,POGZ,SS18,SYP,SYPL1,ADGRL3,KIAA0930,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA6,PCDHGA2,ITGB3BP,TMPO,METTL3,RUSC1,SSBP2,ZKSCAN5,TUBB2A,CLDND1,ZNF177,MAP3K12,RNF103,PHTF2" Coexpression 16135788-Table13 Human Breast_Wang05_410genes_up_BT-BAF57cells GeneSigDB 4.11E-04 1.00E+00 6.83E-03 6.77E-02 49 270 "ADD2,SRPX,PCDH10,VAT1L,CASK,TMEM108,CA4,CA12,LRRFIP1,ZNF521,SIPA1L1,VCAN,BOC,EDIL3,HIPK3,FRY,PCYOX1,IQGAP2,GHR,COPS8,GRB10,GSN,TOX2,NEGR1,LIFR,MATN2,SAMD5,ALDH1L2,NTRK2,OXTR,GNG2,PMP22,PTPN13,PTX3,RASGRF2,RTN1,TNFRSF19,FAM102A,UNC5B,MCF2L2,ST5,SULF2,PLCB1,PCDHB10,SLC44A1,VLDLR,ZNF711,MFF,PLSCR4" Coexpression 18425577-TableS3a Human Breast_Creighton09_594genes GeneSigDB 4.22E-04 1.00E+00 6.99E-03 6.93E-02 73 443 "BRAP,APBB2,BCAS1,CHRD,CA12,CAMK2B,NFS1,LRBA,LRRFIP1,CACNA2D2,RAB26,IQCK,COL4A5,LRIG1,KIAA0040,GREB1,GAPVD1,YTHDC1,FBXL5,FRY,KMT5B,KCTD3,LRRC17,ERBB4,GMPR2,CHST15,ZMYND10,BAIAP2,EVL,NBEA,STAU2,TUBGCP4,HPGDS,GLUL,ELOVL5,HMGCL,IL6ST,MAPT,MATN3,NOVA1,RETREG1,STRN3,ELOVL2,ZSCAN32,NKAIN1,RAD17,ROGDI,RET,ZC3H14,STK32B,GALNT10,CPEB3,SYBU,ABLIM3,IFT122,KDM4B,GLT8D1,DBNDD2,CLSTN2,LARP4,SYT1,TNS2,FRYL,UBE3A,LMF1,NPDC1,ZNF24,REEP1,MAP3K12,DNALI1,SEMA3B,MARCH8,IFT88" Coexpression 17597811-SuppTable7 Human Leukemia_Mullighan07_566genes GeneSigDB 4.22E-04 1.00E+00 6.99E-03 6.93E-02 78 480 "AK2,LTBP4,ALK,DDO,FAM131A,CFLAR,DST,CACNA1I,CA12,CACNA2D1,CAPN3,RUNX1T1,CHGB,HOMER3,CNR1,WHRN,COL4A5,ABCG1,CS,SIPA1L1,DZIP3,PPP1R16B,CTH,DGKG,SCRN1,IP6K1,FEM1B,EEF1D,FRY,MBNL2,KMT5B,FGFR1,FHL1,FOXO3,PDLIM5,CAMKK2,CELF1,GAD1,ARFIP1,PPARGC1A,MCHR1,RNFT2,GUCY1B1,AGBL5,LAMA2,LIMS1,MAN2A2,MEIS1,NBL1,NCAM2,NFE2L2,CNOT4,PCDHGC3,PDE3A,PDE4B,PDE4D,SNX10,RETREG1,SCHIP1,POU6F1,PSMA6,APTX,SNRK,SPDL1,SH3BP2,FHOD3,ARHGEF40,SMARCD3,SPTAN1,ZBTB43,SEPT8,IQCE,DOCK9,TMPO,CHST5,KCNE5,TST,SH3GLB2" Coexpression 16288205-GeneTable2 Human Breast_Charafe-Jauffret06_1233genes GeneSigDB 4.23E-04 1.00E+00 6.99E-03 6.93E-02 121 807 "RALGAPA1,ACTN1,FMNL2,ADCY6,PLEKHH1,KIAA1211,ESYT2,ADRB2,KIAA1324,SRPX,BIN1,PKP4,BCAS1,SFMBT2,RGS20,ATP1A1,ATP1B3,ADGRB2,CFLAR,DST,MTMR2,CA12,HIP1R,CBR1,LONRF2,LARGE1,CACNA2D2,CFL2,CHN2,MAP4K4,SLC4A8,TBPL1,ABCG1,OSBPL3,KIAA0040,RUBCN,GAPVD1,TCAF1,ZFYVE16,MYEF2,SEC16A,DMD,USP3,EGFR,MBNL2,TBC1D16,ST3GAL6,STRADA,FDFT1,FHL1,UBE2E3,EVL,POMT1,MMADHC,COPS8,GNAL,LNX1,GP1BB,TOX2,ICA1,IFI16,INPP1,FAM69A,MAPT,MBNL1,MBP,MT1M,MYCN,MYO6,NACA,NFE2L2,NUCB2,KCTD15,GPSM2,PSAT1,SCHIP1,SH3KBP1,IRX1,PPP2R2C,MAPK9,SLC26A11,SAMD9,ELOVL2,NKAIN1,OXR1,CCDC82,KIRREL1,SGK1,FERMT1,CCDC88A,MTERF2,SMARCC2,KDM4B,ZSWIM8,CLSTN2,POGZ,ITPRID2,RGL1,NSFL1C,PRRC2C,ASTN2,CAMTA1,IQCE,TBL1X,MGRN1,TRPS1,DCBLD1,RUSC1,TTC3,VSNL1,NPDC1,ZNF24,ATP6V0E2,ZNF74,ZBTB38,SH3GLB2,DNALI1,SLC38A1,RNF103,ITM2C,FRMD6" Coexpression M16369 Genes whose expression negatively correlated with resistance of breast cancer cell lines to dasatinib [PubChem=3062316]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.30E-04 1.00E+00 7.09E-03 7.03E-02 18 69 "PLEKHH1,KIAA1324,EPB41L5,CA12,CALM1,SCARB1,EPS15L1,ABCG1,GREB1,MYEF2,SPIN1,ICA1,MAPT,ACSS3,ARX,CBX5,TRPS1,SLC38A1" Coexpression 17880687-TableS4 Human Embryo_Heim07_273genes GeneSigDB 4.30E-04 1.00E+00 7.09E-03 7.03E-02 38 195 "VAT1L,CDC14B,CA12,VAX2,CNR1,AKAP7,CNTNAP2,BRINP1,MEX3B,FLT1,MPP6,IQGAP2,CPLX2,GCNT2,PCDH17,TOX3,LNX1,CHST6,SHC3,MEIS1,PPM1L,NPTX2,PMP22,RET,PRIMA1,SALL1,ANKRD6,LIMCH1,PDZD2,KLHL7,SYN2,PDLIM2,PCDHAC2,TEK,TIMP4,FLRT2,VSNL1,NHSL1" Coexpression 17683608-TableS3 Mouse StemCell_Ulloa-Montoya07_800genes GeneSigDB 4.37E-04 1.00E+00 7.19E-03 7.13E-02 106 692 "ADCY6,PCDH19,APBB2,CHID1,ADAM15,SEC11C,SYNJ1,SGCE,LRRFIP1,LARGE1,CFL2,TPP1,CLTB,LETMD1,MAGED1,C2CD2,ENTPD4,CSF1R,ARHGEF10,VCAN,SOCS5,CST3,TCAF1,DCTN1,C2CD2L,RHOBTB1,CD99L2,CPEB2,PDCD6IP,EDN1,MBNL2,STX2,VPS26C,EXTL2,FAM198B,TAOK3,FECH,AMOTL2,POLK,FOXF2,PCYOX1,FLNC,TMEM175,UFM1,STAMBP,SARAF,GAA,ARFIP1,RAB30,MSL3,GSN,GSTM5,RASSF8,ICA1,JAK2,METTL21A,KIFC3,STXBP5,LIFR,MAN2A2,MEIS1,MEIS2,MKLN1,AFF1,MYO6,NUCB2,ETFRF1,PIK3R1,RETREG1,PMP22,LRP12,MINDY2,RIPOR1,MORC4,CCDC82,TMLHE,ALG9,ATXN7,CPEB3,ARHGEF40,SLC12A4,ARFGAP1,LMBRD1,GLT8D1,DBNDD2,SPART,ITPRID2,ST5,RGL1,DIP2A,ALG1,SATB2,SYNE1,OBSL1,SLC44A1,TUBB2A,UBE2H,TOM1L2,NDRG4,SLC30A4,ZXDA,NT5M,RNF103,ST7,KLHDC1,SENP7" Coexpression 17724462-TableS1 Human StemCell_Nuytten08_1622genes GeneSigDB 4.39E-04 1.00E+00 7.22E-03 7.16E-02 196 1402 "ASIC1,PCDH19,WDR35,MARCH4,OGT,USP37,NCOA1,NUMB,SLC4A4,ATP2A2,AZGP1,FUBP1,C5,BAIAP3,DDR1,CALB1,CAST,SLC16A4,SCARB1,ENTPD6,ZBED1,FOXN3,B4GALT6,ARHGAP22,LHX2,RAB28,PPT2,NGEF,FBXO7,ABCG2,QKI,MAP4K4,CNN3,IQCK,MAGED1,TBPL1,COX4I1,NECTIN3,CPS1,CLOCK,CREM,ENTPD4,ABCG1,OSBPL3,PHACTR3,DZIP3,FAM131B,KIAA0408,KCTD8,DGKG,SCRN1,SPOCK2,NR1D2,DMTF1,SLC12A6,DPYSL2,TOM1,TSPAN5,PHC2,ANKRD46,TMTC1,YAF2,APH1A,EGFR,MBNL2,EIF4G2,STARD3NL,ENO2,VPS13B,SPEG,KATNAL1,DLC1,ST3GAL6,FER,FGF1,OLFM1,FGF13,FHL1,SYNCRIP,TMEM107,PDLIM5,FAM49B,STAMBP,USP21,PRELID3A,CGREF1,DENND2A,GAD1,ARFIP1,SESN1,MALT1,KIAA1958,GRB10,ADAMTS13,SOX21,ADAMTS6,HAS2,HBA1,PACSIN2,HMGCR,HP,IFI16,RBPJ,IL6R,IL6ST,ITPKA,GATD1,KHK,KIF2A,KTN1,TTYH2,LAMP2,LIFR,LIMS1,MATN2,MEST,KITLG,NRBP2,MX1,MXI1,NPTX1,OGG1,ETFRF1,PDE4A,SERPINI1,PKD1,XRN1,PCDH18,EPB41L4B,PPP3CC,CEP41,GDPD1,SAMD9,PTN,RAP1GDS1,ENOX1,RGS4,RNASEL,EXD2,ROBO1,SPIN3,RYR3,SAFB,SEC14L1,GALNT10,SH3BGR,ST6GAL1,SLC6A8,SLC12A2,BTBD7,OGDHL,SNCA,KIF13A,TMCC1,PDZRN3,TRERF1,NMNAT2,ERC1,DBNDD2,RBM26,ZNF302,THSD1,SSTR1,SYNE2,ARHGEF9,NUDT10,SYN1,TACC1,TBL1X,TCF4,ZEB1,TCF12,PUM2,DICER1,TMEM121,ZNF106,SLC44A1,TIAM1,LRRC8A,TMPO,TSC1,TUBB1,WIPF1,XRCC4,PCDH20,LYPD6,DPYSL5,ANKS1B,DHX33,PRTFDC1,RTN4,NLRP3,RNF146,ST8SIA2,ZNF30,CPNE4" Coexpression 12734205-TableS2 Human Ovarian_Wood03_445genes GeneSigDB 4.43E-04 1.00E+00 7.27E-03 7.21E-02 60 349 "AS3MT,SPARCL1,PPP4R4,TMEFF1,NCOA1,RASL11B,DOCK11,BID,NAE1,CAPN3,CBR1,DCLK1,NPIPA1,LETMD1,CNRIP1,SIPA1L1,RASSF2,EDNRA,KLHL5,PLXNC1,TMEM35A,STARD3NL,KATNAL1,ACSL4,SMC2,KHDRBS3,RAPGEF6,IRAK3,HAS2,HMGCR,KLHL23,IPO5,LYPLAL1,MEST,GIT1,NEFH,SLC11A2,NTRK3,PDCD2,MTRF1L,QDPR,FAT4,ERI2,PRCD,NUBPL,LIMCH1,PDZRN3,SSTR1,TAF6,TEK,HEY1,SSBP2,SLC35A4,UCHL1,FLRT2,BCL2L13,KCNT2,ZNF45,ZBTB38,FRMD6" Coexpression 16397240-SuppTable5 Human Colon_Grade06_85genes GeneSigDB 4.49E-04 1.00E+00 7.35E-03 7.29E-02 16 58 "ABCF1,FZD9,UNC5A,ADGRF5,LDB2,UBE2L6,AKAP6,DGKB,MED12L,ZDHHC15,HP,DISP2,MSR1,MYCN,ZNF568,ZXDA" Coexpression M1797 The glioblastoma multiforme (GBM) plasticity signature: genes down-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.49E-04 1.00E+00 7.35E-03 7.29E-02 16 58 "NDRG2,CADPS,COL9A3,PCOLCE2,EPHB1,PSD2,PADI2,ITGA7,LSAMP,MAPT,ZDHHC14,RNASE1,PCMTD2,DZIP1,SYN2,TST" Coexpression M1726 Transcripts showing subcellular localization only to proximal dendrites in the adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.61E-04 1.00E+00 7.52E-03 7.46E-02 12 37 "ANK2,CHGB,SULT4A1,GPD1,MAP2,NNAT,NECAB2,SNRPN,MTCH1,PLPPR2,SLC17A7,NETO1" Coexpression M8896 Genes up-regulated in multipotent progenitors versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 7.52E-03 7.46E-02 34 169 "ACTN1,CHN1,IPCEF1,RIPOR2,RASSF2,ARMCX2,KLHL3,PHF20L1,PLEKHA1,LRRC17,REEP2,CHST15,PDLIM5,AP4B1,AGFG1,IGF1,MBP,HS6ST3,SLC11A2,PDCD2,SH3KBP1,SLC26A11,STK32A,ZSCAN2,TTC13,EMID1,SATB1,ST6GAL1,DZIP1,ST8SIA1,PJA1,GPRIN3,LRRC8A,SSBP2" Coexpression M10605 Genes down-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.62E-04 1.00E+00 7.52E-03 7.46E-02 34 169 "ACTN1,NCOA1,BOC,RCAN1,EDNRA,ERBB4,SPEG,EXTL2,KATNAL1,MRVI1,DLC1,PPP1R1B,FHL1,FLNC,COPS8,FERMT2,LAMA2,NPR2,PCDH18,CEP41,MAPK7,RGS4,SLC4A3,LIMS2,SNRPN,ZBTB43,MPRIP,OBSL1,TPM2,TTC3,VSNL1,NAV3,RTN4,MSRB3" Coexpression M10016 Genes up-regulated naïve CD4 [GeneID=920] T cells: Ly6c+ versus Ly6c-. MSigDB C7: Immunologic Signatures (v6.0) 4.64E-04 1.00E+00 7.55E-03 7.48E-02 37 189 "C3orf14,PTCHD1,PCDH19,ALCAM,TMEM108,ZNF583,GPRASP1,KIF26A,ARRDC4,EDIL3,RGS17,ENO2,RCAN2,EPHB1,RAB9B,EZH1,CHST15,ACSS1,MSL3,HLF,CPT1C,DPY19L2P2,GPR85,SERPINI1,NALCN,ZNF655,HYDIN,QDPR,TMEM200C,ERC1,ZNF621,ZNF610,CCDC14,CLDND1,TCEAL7,LAMP5,JPH3" Coexpression 14695196-Table4 Human Colon_Mariadason03_308genes GeneSigDB 4.69E-04 1.00E+00 7.61E-03 7.55E-02 42 223 "SEMA7A,ATP1B3,NAE1,MYL6B,CLTB,CSNK1E,GREB1,SEC14L5,LONRF1,EGR3,PLXNC1,EIF5,FCGRT,ANKFY1,GAA,SPIN1,PSIP1,MAP4,MEF2C,MGAT3,MITF,NNAT,SLC11A2,PDE4D,ABCB1,APTX,RFX2,ZNF532,ZC3H14,OGDHL,ZHX3,GLT8D1,CLASP2,SST,KANK1,ARC,TCF4,ICAM5,TTC3,HIRA,UCHL1,EVI5" Coexpression M17621 Genes up-regulated 9 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.69E-04 1.00E+00 7.61E-03 7.55E-02 42 223 "CLK4,TMEFF1,ARNTL,BACH1,PTBP2,CARS,RCHY1,CREM,RBM39,CTH,DMTF1,RCAN1,KMT5B,EIF5,IP6K2,FOXO3,ZNF44,GAD1,ZNF274,BTN2A1,IFI16,LIG4,MARK3,NEK1,CNOT4,ZNF426,STRN3,ING3,PTN,RBBP6,RIC8B,YY1AP1,ZNF331,SUPT20H,CHD9,KDM3A,AGTPBP1,ZNF23,ZNF45,ZNF184,ZNF195,JMJD1C" Coexpression M9824 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 4.77E-04 1.00E+00 7.71E-03 7.65E-02 38 196 "GAS7,NCOA1,ZNF555,RCBTB2,AATK,SEC24C,ARHGAP24,JAKMIP2,SEZ6L2,PSMA3-AS1,GTF2IRD2,UBE2E3,ADAM28,CNTRL,MARK3,MEF2C,MSR1,RTL5,SFR1,SMIM11A,ING3,SNRK,ZSCAN32,PID1,REV3L,CCDC112,SAFB,NSFL1C,TACC1,CYB561A3,TLR4,PIK3R5,CDK20,DCBLD1,SGK3,CLIP2,TFIP11,IFT88" Coexpression M7410 Genes down-regulated in immature neuron cell line: control versus interferon alpha (6h). MSigDB C7: Immunologic Signatures (v6.0) 4.77E-04 1.00E+00 7.71E-03 7.65E-02 38 196 "NDRG3,ADRB2,USP35,ST3GAL5,CASTOR3,ARHGEF1,CDC25B,PLEKHB1,IPCEF1,RIPOR2,SNPH,PITPNC1,NR1D2,OPTN,ING4,EZH1,HPCAL4,FYB1,SESN1,NTNG2,PRRC2B,MBP,MXI1,PDE4D,PFKFB4,PIK3R1,SLC26A11,GRAMD1C,GAL3ST4,FAM102A,NBPF1,SIRT2,EPC1,SYNE2,ZMAT3,WNT7A,ITM2C,FAM219B" Coexpression M1746 Genes with promoters bound by FOXP3 [GeneID=50943] and which are up-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.77E-04 1.00E+00 7.71E-03 7.65E-02 38 196 "LDLRAD4,CAST,LRIG1,ARHGEF10,IPCEF1,TBC1D5,GPHN,SLC37A3,RAPGEF6,SESN1,MALT1,DBF4,AP4S1,FAM69A,MBNL1,MYO9A,PDE4B,PIK3R1,STRN3,PPP3CC,RFX3,TRA2B,CHD9,WDR37,SLA,ZKSCAN3,CDK19,ANKRD12,TCF12,GPRIN3,SIK3,KAT6B,TRIO,RUNDC3B,TBC1D15,EVI5,PHTF2,JMJD1C" Coexpression M2395 Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.94E-04 1.00E+00 7.97E-03 7.90E-02 33 163 "NDRG2,SPARCL1,DCLK1,CNR1,ZNF521,AKAP12,CSF1,SV2B,DNM1,EGR3,EPB41L2,FGF13,FGF14,SCARA3,CHL1,CPLX1,STMN2,GUCY1A1,ACOT7,ITGA7,KCND2,MAP4,MEIS2,DUSP26,PMP22,SEPT4,PTN,PTPRO,RNASE1,ZFHX4,SNCA,UCHL1,FSTL5" Coexpression M2372 Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-1 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.98E-04 1.00E+00 8.02E-03 7.95E-02 15 53 "CLTC,CNN3,CREM,E2F5,EDN1,SYNCRIP,ARFIP1,SMAP1,IGF1,PMP22,PRKACB,FNDC3A,KAT6B,UBE2H,TBC1D15" Coexpression M18095 Up-regulated genes from the set G (Fig. 5a): specific to cells expressing both MLL-AF4 [GeneID=4297;4299] and AF4-MLL fusion proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.27E-04 1.00E+00 8.45E-03 8.38E-02 44 238 "KDM5D,SPARCL1,SYT13,PHYHD1,CBR1,KYAT1,P2RX6,UBE2L6,CHGB,FAM189A2,IGDCC3,CRMP1,PHF14,IRAK4,SRPK3,EPB41,NCALD,NSG1,INPP5K,GPR162,LYVE1,GNG4,NEGR1,IGF1,MAPT,LYRM9,LINC00672,NF1,RELN,GDPD2,PTPRO,EMID1,TET1,ABTB1,PEG10,SMG6,LRRC8A,TTC3,UCHL1,LYPD6,CELF4,SPIRE1,DOCK8,KAT6A" Coexpression M4687 Genes down-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.29E-04 1.00E+00 8.45E-03 8.38E-02 38 197 "ACTN1,SFMBT2,PPP4R4,LINC00173,MARCH3,BBS2,PTBP2,LARGE1,CCDC144A,KLHL3,SEC16A,E2F6,SNX29,PAN3,ERBB4,KCNQ3,HECTD2,LYRM9,IDNK,SLC11A2,PCSK5,PIK3C2A,RETREG1,DRAM2,C1orf54,FAM184A,GAL3ST4,SEPHS1,GKAP1,KIF13A,MYCBP2,SPART,SSBP2,XRCC4,ZNF23,LOC100506497,ACTR3B,KLHDC1" Coexpression M5544 Genes up-regulated in comparison of B cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.29E-04 1.00E+00 8.45E-03 8.38E-02 38 197 "AMPD3,NUMB,BAIAP3,CACNA1A,COPB2,PPP1R16B,CYBB,RASSF2,SCRN1,ARMCX2,ZNF804A,E2F5,CHST15,SEC23B,SYT17,BACH2,IRF8,LMO2,MEF2C,MKLN1,PCDH9,FA2H,ZSCAN32,ZDHHC4,DGLUCY,MAPK12,SEC14L1,CASC3,GALNT10,SHMT2,SYPL1,FBXW11,TCF4,USP22,TST,LAT2,FTSJ1,LAMP5" Coexpression M4164 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 5.29E-04 1.00E+00 8.45E-03 8.38E-02 38 197 "GPRASP2,BIN1,ARRB2,LINC00173,ST3GAL5,TPP1,TBC1D5,CPEB2,MBNL2,KCTD3,TENM1,PTK2B,GTF2IRD2,GABBR1,PRDM5,PTPRT,ITGAM,LYRM9,PCSK5,PDE4D,ENPP2,RETREG1,PPP3CC,SUSD4,ROGDI,RFX3,FNIP1,HKDC1,CHD9,GKAP1,AGTPBP1,NEU4,FAM200B,ZNF34,AKTIP,KAT6B,PIK3R5,TPM2" Coexpression M7397 Genes up-regulated in the neuron cell line: immature versus mature. MSigDB C7: Immunologic Signatures (v6.0) 5.29E-04 1.00E+00 8.45E-03 8.38E-02 38 197 "TXNDC16,APBA2,ARNTL,ST3GAL5,ENTPD4,IPCEF1,RIPOR2,SPOCK2,USP3,NR1D2,RASGRP1,PAN3,FOXO3,ACSS1,PRRC2B,GSN,MBP,LYRM9,ZNF862,NF1,PIK3R1,POU6F1,PPP3CA,KANSL1,VPS13C,ZSCAN2,GAL3ST4,ATXN7,RASA3,FAM102A,POGZ,SYNE2,PIK3R5,TSC1,RNF103,MPPE1,MARCH8,SENP7" Coexpression M2635 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable ERBB2 [Gene ID=2064]. MSigDB C6: Oncogenic Signatures (v6.0) 5.29E-04 1.00E+00 8.45E-03 8.38E-02 38 197 "RALGAPA1,MAP4K3,ZBTB10,MPDZ,CALB2,PTBP2,COL9A3,LRIG1,GREB1,RASGRP1,MBNL2,EGR3,KCTD3,ARMCX1,DLC1,FKTN,DBF4,GPER1,JAK2,MATN2,NRCAM,FAM216A,C1orf109,RBBP8,ERI2,RMI1,HSPA4L,ZNF430,PEG10,ITPRID2,SS18,KANK1,ANKRD12,MTCL1,TIAM1,ACTR6,HIRA,WIPF1" Coexpression 19334046-TableS3b Human Lung_Boelens09_135genes GeneSigDB 5.30E-04 1.00E+00 8.46E-03 8.39E-02 24 106 "OSBPL6,CC2D2A,CEP126,STK33,BBS2,CAST,RGN,LRWD1,NCOR2,LRIG1,PPP1R16B,DNAH9,ZMYND10,AK8,ACSS1,GPR162,AFDN,EXOSC10,FHOD3,EPN2,SLC22A4,SYNE1,TPM2,TUBB2A" Coexpression M2504 Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were not affected by p38 inhibitor LY479754. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.31E-04 1.00E+00 8.46E-03 8.39E-02 58 337 "ABR,CLK4,MTUS1,C1QTNF1,AMPD3,KCNAB2,ARRB1,ZBTB10,NRP2,BID,CFLAR,CA12,CARS,C2CD2,CSF1,LRIG1,VCAN,DOCK4,RCAN1,OPTN,EGFR,TUBD1,ETV1,AMOTL2,PDLIM5,TRIM16,SRCAP,HTATSF1,ADGRA3,SLC2A6,IL6ST,SMAD1,MEF2C,MEIS2,MID1,OXTR,PDE4A,SMOX,ING3,RIPOR1,RGS3,ZFHX4,ROBO1,SGK1,ABLIM3,ARHGEF40,SLC22A4,INAVA,FNBP1,PEG10,SSTR2,DNMBP,HEY1,TRIO,SSBP2,CLIP2,ADAMTS9,NETO2" Coexpression M7778 "Genes down-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.43E-04 1.00E+00 8.63E-03 8.56E-02 14 48 "ARRB1,CNR1,DZIP3,ZFYVE16,JAKMIP2,PIPOX,IQCG,MYCN,NRCAM,NKAIN1,PDZRN3,ARHGAP26,ASTN2,AKTIP" Coexpression M2878 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 5.43E-04 1.00E+00 8.63E-03 8.56E-02 14 48 "CALB1,CDR1,CHGB,DOCK4,SNAP91,DYNC1I1,ETV1,ST3GAL6,NRCAM,PCDH8,RELN,SNAP25,LMO3,HEY1" Coexpression 17711579-Figure1 Human Testicular_Duale07_100genes GeneSigDB 5.50E-04 1.00E+00 8.72E-03 8.65E-02 20 82 "USP6NL,USP3,HEYL,TNK2,ANKFY1,FYN,MEGF10,PRDM5,IL6ST,NF1,SLC25A36,ZNF334,GKAP1,DMXL2,PCDHB9,TRIO,TRO,PCDH20,ZFP37,NAV3" Coexpression M7009 Genes up-regulated in IKZF1 [GeneID=10320] knockout: lymphoid-primed multipotent progenitors versus megakaryo-erythrocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 5.53E-04 1.00E+00 8.76E-03 8.69E-02 33 164 "ACTN1,ADCY6,TNRC6C,SFMBT2,CNN3,LRIG1,HDAC4,PLEKHA1,SLC43A2,CHST15,RAPGEF6,SESN1,TDRKH,MAP4K5,BACH2,IL6ST,SMAD1,ZC3H12B,SLC11A2,PLCB2,EML5,CEP97,BEND5,ST6GAL1,DZIP1,ST8SIA1,TET1,CEP68,ZEB1,SSBP2,TTC3,TOM1L2,KLHDC1" Coexpression M8696 Top 40 genes from cluster 7 of acute myeloid leukemia (AML) expression profile; 61% of the samples are FAB M1 or M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.76E-04 1.00E+00 9.12E-03 9.04E-02 10 28 "CLCN3,GAPVD1,EPB41,KCNH2,SLC6A8,SPTB,TAL1,TNS1,TPM1,OSBP2" Coexpression 19286929-SuppTable2n Mouse Lung_Rangasamy09_254genes GeneSigDB 5.77E-04 1.00E+00 9.12E-03 9.04E-02 44 239 "ADCY6,TAOK1,ARHGAP20,CASK,BTK,KALRN,LRBA,MAGI1,TAOK2,SIPA1L1,SOCS5,DOCK4,GIT2,SRPK3,CALCRL,DLC1,GPR34,GUCY1A1,GUCY1B1,IRAK3,ITPKB,GPR155,GPR85,GPSM2,MAPKAP1,PILRA,SH3KBP1,PPM1B,PPP2R5E,PRKCB,PTPRD,PTPRO,KHDRBS2,RGS3,RGS4,KIF13A,TMCC1,ADGRL3,ARHGAP9,TIAM1,RASD2,P2RY12,WNT7A,FZD3" Coexpression M5313 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 16 h versus those from old donors treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 5.86E-04 1.00E+00 9.20E-03 9.12E-02 38 198 "AMPH,MAP4K3,CDK10,PTCH2,DST,PPT2,FAM149A,BRINP1,PLPPR4,EXOG,DMD,ABCA8,FDFT1,PDLIM5,PRELID3A,TUBA8,MSTN,GNAO1,GSTT2,KCNQ3,FXYD7,POLG,PPP2R2B,ZDHHC14,CCDC102B,MCMBP,PUF60,MYO16,TEX2,ATP10B,ELOVL4,ANKRD28,DNMBP,PCDHB6,CDK20,ELP5,BCL2L13,ADAMTS9" Coexpression M8379 Genes down-regulated in CD4 [GeneID=920] T cells: progesterone [PubChem=5994] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]. MSigDB C7: Immunologic Signatures (v6.0) 5.86E-04 1.00E+00 9.20E-03 9.12E-02 38 198 "ABCD2,PLA2G4C,MPDZ,USP2,SLC16A4,CRLF1,B4GALT6,CLTC,LY86,NSL1,CLIP3,PPP1R16B,KIAA0040,GREB1,RHOBTB1,DMD,EIF1,NCALD,F5,DLC1,ATP6V1H,CGREF1,STAU2,GCNT2,CNTRL,GRB10,ITGAM,MATK,PCDH8,TCP11L1,FNDC3A,ST6GAL1,TIAM1,TP53BP2,DNALI1,EVI5,CIAPIN1,SLC17A7" Coexpression M8034 Genes down-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]. MSigDB C7: Immunologic Signatures (v6.0) 5.86E-04 1.00E+00 9.20E-03 9.12E-02 38 198 "ADCY8,ADRA1B,CASK,ARNTL,MARCH3,ARHGEF7,ARHGEF1,CBFA2T2,ENTPD6,CDR1,GPRASP1,ZNF337,SPOCK2,KIAA0753,ABCC5,TENM1,ING4,PTK2B,AKAP3,GABRB3,INPP5K,STON1,RETREG1,PLXNB1,FSD1,GRAMD1C,STK32B,MAP6D1,SATB1,SCN8A,SH3GL3,HKDC1,SLA,ARFGAP1,KDM4C,RUSC1,PLPPR2,MPPE1" Coexpression M6731 Genes down-regulated in spleen dendritic cells from healthy mice: 33D1+ versus DEC205+ subpopulations. MSigDB C7: Immunologic Signatures (v6.0) 5.86E-04 1.00E+00 9.20E-03 9.12E-02 38 198 "TBC1D14,ALCAM,DPY19L3,GPR146,PROM1,SYNJ2,LDLRAD4,CA8,CABP7,ZBED1,CHN2,RAB33A,ABCG2,KIF26A,CHRDL1,ARRDC4,EXTL2,MAD2L2,ERGIC3,GAD1,RAB30,GPD2,ADAP1,STON1,RNFT2,PACSIN2,HMGCL,INPP1,KIT,PDE4A,PTCH1,SARS,FAM102A,SLC22A4,INTS9,RGL1,TACC1,TUBB2A" Coexpression 18318837-TableS1 Human MesenchymalStemCells_Yamamoto08_1252genes GeneSigDB 5.91E-04 1.00E+00 9.28E-03 9.20E-02 126 853 "NDRG2,RNF157,KIAA1211,ADRA1B,MTUS1,AGT,SPARCL1,BBOX1,SYT13,DDO,APOC1,APOC2,BCAS1,SEMA4G,ARSE,ASGR1,ASPA,AZGP1,BCHE,RGS9,PROM1,C5,THSD7A,CD86,LONRF2,MS4A7,LHX2,NGEF,FAM189A2,COL4A5,GAL3ST1,GDA,FAM169A,PLCXD3,CYBB,RIPOR2,RASSF2,DAPK1,AIF1L,FAM107B,SLC25A18,EDNRB,HEYL,PLXNC1,ADGRV1,HSPA12B,F5,FCGR1B,FCGR3A,PPP1R1B,FGF13,FGF14,FGFR3,FOLH1,ABLIM2,GALNT15,DENND2A,IP6K3,IQGAP2,SYT17,GATM,ALDH1L1,SULT1C4,PPARGC1A,AIFM3,KIAA1958,STMN2,GUCY1A1,VSIG4,HP,ICA1,IRF8,IGF1,KNDC1,ITGA7,KLHL23,KCNJ16,KHK,PIK3AP1,MARK1,LRP1B,SRSF12,MGAT3,SAMD5,MYO7A,NCF2,NPTX2,PCBP3,NRCAM,P2RX7,ABCB1,DUSP26,SNX10,RETREG1,FXYD1,SEPT4,PTH1R,PTPRE,ACSM5,FAM184A,BEND5,GLDN,SALL1,HKDC1,ST6GAL1,ST8SIA1,CXXC4,GKAP1,OGDHL,DMRTC1,SNAP25,KANK1,TMEM150C,COBL,WSCD1,NEU4,CUX2,SLC19A3,PCDHAC2,RUNDC3B,TRIM9,ADAMTS9,SIGLEC10,WNK3,DOCK8,ADAMTSL3" Coexpression 17724462-Table1 Human StemCell_Nuytten08_44genes GeneSigDB 6.06E-04 1.00E+00 9.50E-03 9.41E-02 12 38 "PCDH10,YAF2,RPS6KC1,GRIA2,GRM8,COMMD5,NME4,MAPK7,DIRAS2,EPN2,DIP2A,NETO2" Coexpression 18223198-Table5 Human Brain_Chen-Plotkin08_40genes_GRN+ FTLD-U GeneSigDB 6.08E-04 1.00E+00 9.51E-03 9.43E-02 11 33 "ATP1A3,ECM2,EGR3,ABCA8,STMN2,LAMP2,PCDH8,PCSK1,RGS4,SYT1,ZIC1" Coexpression 15860227-Table1b Human Immune_Inomata04_15genes_down GeneSigDB 6.08E-04 1.00E+00 9.51E-03 9.43E-02 7 15 "CDC42BPA,GAS7,DDO,MYRIP,SEC14L1,FAIM2,DICER1" Coexpression M8922 Genes up-regulated in CD4 [GeneID=920] T cells: Th1 versus Th17 negative. MSigDB C7: Immunologic Signatures (v6.0) 6.21E-04 1.00E+00 9.70E-03 9.62E-02 27 126 "JAZF1,CD38,IGDCC3,IPCEF1,EIF5,MED12L,FGFR1,CSPG5,STAU2,PCDH17,MALT1,RNPS1,IRAK3,SFXN5,P2RY1,SPDL1,PTPRO,PID1,TMEM255A,SLC25A36,NUDT11,SCN7A,LARP4,ERBIN,APOM,TCF12,CPNE4" Coexpression 18849563-SuppTable5a Human Lung_not_cancer_Bhattacharya09_84genes_COPDvsControl GeneSigDB 6.24E-04 1.00E+00 9.72E-03 9.64E-02 18 71 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,UBTF,ZNF177" Coexpression M6616 Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [GeneID=79923] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.29E-04 1.00E+00 9.79E-03 9.71E-02 143 988 "ACADM,AXIN2,AP2A1,OSBPL1A,ALCAM,PARG,CDC14B,IGDCC4,RASL11B,TMEM108,RIPK1,MPDZ,BMP7,CA4,CACNA1A,CACNA2D1,CALB1,SPAG9,RUNX1T1,NFS1,CDH2,LARGE1,FOXN3,B4GALT6,CNOT8,EPS15L1,CNN3,IQCK,COL4A5,ZNF521,PREPL,RBM39,NCOR1,CS,CSNK1E,VCAN,PPP1R16B,FAM131B,TCAF1,KIF26A,TMEM170A,MYEF2,LYPD1,WDR20,USP3,MED12,DPYSL2,ACOT8,DTNA,AASDH,KLHL5,SUGP2,APH1A,EIF4G2,ING4,ERBB2,MRPL37,PIPOX,EXTL2,ARMCX1,ACSL4,FGFR1,FOXO3,APOPT1,UFM1,TRIM16,SARAF,MPP6,OGA,TCERG1,TNRC6A,MSL3,POLL,DIDO1,GSTT2,LINGO1,HAS2,SHISA6,IDH3A,IFI16,KCNN2,HECTD2,MOV10,ENPP2,KCTD15,SMIM7,DRAM2,MINDY2,WBP1L,PTN,ZSCAN32,ZIK1,PEX2,PPP2R3C,C1orf54,RASGRF2,RIC8B,EXD2,ALG9,GSTCD,MRAP2,ADAL,RYR3,ZNF331,FAM192A,SALL1,SGK1,FERMT1,SNRPN,KDM3A,SP2,SPART,LHPP,APOM,KANK1,DNAJC9,TAL1,FBXW11,TBL1X,KLHL4,SIN3B,OBSL1,SLC44A1,TIAM1,TIMP4,CBX5,FAM124A,R3HDM1,SSBP2,SGK3,UBC,EIF4ENIF1,VLDLR,CFAP298,ZIC1,ZIC2,SMARCAD1,MAP3K12,URM1,KAT6A,PHTF2,RSPRY1,FXR1" Coexpression M2736 Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of EED [Gene ID=8726] gene. MSigDB C6: Oncogenic Signatures (v6.0) 6.33E-04 1.00E+00 9.84E-03 9.76E-02 37 192 "ADRA1B,ADGRF5,BACH1,MPDZ,PTBP2,CCK,CLGN,C2CD2,HINFP,AATK,HDAC9,ARHGAP24,DMD,ANKRD46,KMT5B,RASL12,CORO2B,RAB40B,GPR37,PTPRT,NXPH3,IRF8,IL12A,ENPP2,CCSER2,PDZRN4,KLK6,REV3L,CLIP1,SEMA6D,SATB1,BTBD3,ZHX3,TRPS1,ZNF177,EVI5,PLSCR4" Coexpression 16210406-table1 Human StemCell_Jaatinen06_86genes GeneSigDB 6.42E-04 1.00E+00 9.89E-03 9.80E-02 19 77 "OSBPL1A,ALCAM,DST,MAGI1,SOCS6,SMARCAL1,CRHBP,RHOBTB1,GCNT2,ADAM28,ADGRA3,HLF,ICA1,LMO2,SYTL4,CYTL1,PTPRD,CBX5,TRO" Coexpression M8408 Genes down-regulated in dendritic cells: CD8+ spleen versus brain. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ADCY8,AGT,NCOA1,ATP2B2,BMP7,CBARP,CHN1,IQCK,AHCTF1,PPP6R2,DGKB,ZNF804A,RUSC2,C2CD2L,DTNB,EPHB1,EYA1,SCML2,OLFM1,GCNT2,ARFIP1,GPR12,STON1,GPR37,KCNN3,LIFR,LMO2,SMAD9,MX1,NPR2,PLCD1,MINDY2,ATXN7,SLC2A5,MAPKBP1,SOX15,RGL1,SLC30A4" Coexpression M4606 Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ARRB1,ZSCAN18,ST3GAL5,CHN2,CRY2,CYBB,GPRASP1,ZFYVE16,STX2,FCGRT,LILRB4,GSN,SLC2A6,HNMT,IRF8,MSL1,P2RY13,NELL2,SLC11A2,LRP12,PTPRE,C1orf54,RNASE1,RTN1,SLC2A5,CCDC88A,ZNF415,TEX2,RGL1,KANK1,TCF4,ZNF34,NACC2,BEX4,NPL,TTC3,ITM2C,NLRP3" Coexpression M8421 Genes up-regulated in brain microglia versus spleen CD8- dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "NDRG2,NUMB,ATP2B2,MTMR2,CCNT1,CHN1,QKI,DGKB,ECM2,SEMA3D,FRY,ERCC2,MPP6,ARFIP1,TOX3,STARD3,STON1,GUCY1A1,RBPJ,KCNN3,LIFR,LMO2,LSS,SMAD9,MX1,MYO5A,NPR2,NPTX1,POLR2F,CNNM2,SP4,VPS13A,ANKRD12,MTCL1,VSNL1,EVI5,RNF103,ST7" Coexpression M5295 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "RALGAPA1,NDRG3,KIAA1324,BIN1,THSD7A,CBFA2T2,ARHGEF6,AKAP7,RIPOR2,TBC1D5,PITPNC1,KLHL3,USP3,DOCK2,RASGRP2,EYA1,FCGRT,FYB1,GNAO1,KCNH2,MXI1,NELL2,NF1,NFYA,PCBP3,NUCB2,PDE4D,ENPP2,PLCD1,PRKCB,ZNF331,MYCBP2,MCF2L,SSBP2,WNT7A,ZNF711,MARCH8,NLRP3" Coexpression M4167 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ADCY5,GPRASP2,BIN1,LINC00173,ST3GAL5,CFL2,MAP4K4,PNPLA8,PITPNC1,KLHL3,NR1D2,SNX29,MBNL2,KCTD3,TENM1,RASGRP2,GTF2IRD2,GABBR1,MXI1,LYRM9,PCSK5,PDE4D,PNMA3,DRAM2,MINDY2,PPP3CA,PPP3CC,ZNF844,SUSD4,TRAPPC13,FNIP1,HKDC1,GKAP1,AGTPBP1,FAM200B,ZNF34,TPM2,ZNF711" Coexpression M3668 Genes up-regulated in comparison of control macrophages versus macrophages treated with interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "TBC1D14,ATP6V0A1,GPR146,GIT2,DBT,ELMSAN1,ABCC5,FAM13A,EPB41,PRAM1,ZNF589,BAIAP2,AGAP3,TMEM175,STAMBP,CBX1,TMEM121B,METTL21A,MEF2C,SFR1,MBOAT7,DRAM2,PRPSAP2,REV3L,PCMTD2,ZC3H14,RXRA,RASA3,KDM3A,DNAJC9,KIAA1107,TCF12,ARHGAP9,NACC2,TP53BP1,ELP5,HPS4,PDSS2" Coexpression M9574 Genes down-regulated in cells from peripheral lymph nodes: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ADD2,MTMR2,GYG2,CA12,PRC1,ENTPD6,NPIPA1,CNTN1,ENTPD4,RNF14,DBI,FIS1,ENO2,CHST15,SCARA3,RAB40B,DIDO1,ADAM11,MITF,NRCAM,TMOD2,PLXNB1,EPB41L4B,PEX2,ZNF331,GALNT10,CDK19,ANKRD28,PDLIM2,TBL1X,USP22,PCDHA3,NACC2,TRIO,TTC3,MTCH1,VLDLR,TUBA1A" Coexpression M9928 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 1h. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "UNC79,TRMT9B,RASL11B,MYOM1,CA4,KRIT1,SLC16A4,CDH2,PCYT1B,SUMF2,CNTNAP2,DOCK4,YTHDC1,FBXL5,SEZ6L2,WDPCP,HIPK3,MRO,EIF4G2,EIF1,RASL12,CD320,FOXF2,CGREF1,RAB30,GPR75,DIDO1,RABL2A,ADAMTS6,ICA1,MMP17,PTX3,CNKSR2,CEP68,CD27-AS1,PCDHB15,VSNL1,POLR3H" Coexpression M5022 Genes down-regulated in comparison of myeloid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "AGT,AMT,PLA2G4C,CFLAR,BMP7,COL4A5,NRG2,SNCAIP,PITPNM3,KIAA0040,SGSM2,DTNB,SEZ6L2,EDNRB,CNNM1,SRPK3,GNAL,HNF4G,RBPJ,IL12A,FAM69A,KCNN1,LMO2,NEFH,DPY19L2P2,PDCD2,ENPP2,GPR173,DCHS2,RAD51D,RNASEL,CLIP1,SH3GL3,FUZ,RUNDC3B,XRCC4,TUBA1A,PARP11" Coexpression M8743 Genes down-regulated in STAT5 double knock-in T cells: control versus IL2 [GeneID=3558] stimulation for 17h. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "USP31,ARRB1,ALDH7A1,CAPN3,CDC25B,AKAP5,MAGED1,PUM1,MYADM,RIPOR2,SPOCK2,RHOBTB1,EXOG,RASA4,CORO2B,FUT9,SARAF,SRCAP,ATOH8,IRAK3,NOVA1,SMOX,MCMBP,SCP2,SEC14L1,SHMT2,ANKRD6,ABLIM3,SLC9A5,RBM34,DOP1A,SPTAN1,TAF6,TBL1X,HEY1,TTC3,FLRT2,CLDND1" Coexpression M6652 Genes down-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL6 [GeneID=3469] and LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ABCD2,PITPNM2,CA12,RHBDL1,LONRF2,KCNAB3,HECTD1,ARHGEF10,PLPPR4,SLC25A18,IRAK4,VPS26C,EFCAB2,PCDH17,HPGDS,TNRC6A,ZHX1,FRMD5,FRMD3,HLF,KCNN1,KCNQ3,CHST6,PPP2R2B,KANSL1,TMEM104,PID1,LIMS2,WDR47,SPTB,SLC37A2,TBL1X,WBP2,OSBP2,KCNK12,XRCC4,EMX2OS,SENP7" Coexpression M7779 Genes down-regulated in macrophages: untreated versus 48h after M. bovis BCG infection. MSigDB C7: Immunologic Signatures (v6.0) 6.47E-04 1.00E+00 9.89E-03 9.80E-02 38 199 "ADGRB1,BBS2,NRP2,BAIAP3,CACNB4,FBXO7,COL9A3,MAGED1,CLOCK,ABCG1,LRIG1,INTS1,CPEB2,FRY,EIF4G2,FGFR1,DCLK2,SCIN,IL6R,KIT,L1CAM,LAMP2,LSAMP,PPM1L,PDCD2,PTCH1,BEND5,ADAL,FOXRED1,PDZRN3,SPTAN1,POGZ,STX1A,SLC37A2,TAL1,RGMB,UBC,WRN" Coexpression M8617 Potential direct target genes for MIR34A [GeneID=407040] microRNA in IMR32 cells (neuroblastoma). MSigDB C2: CGP Curated Gene Sets (v6.0) 6.73E-04 1.00E+00 1.01E-02 1.01E-01 30 146 "TMCC3,HACE1,AK2,PKP4,RAB29,CALB1,NUMBL,TMEM184B,PPP1R16B,PNPLA8,EARS2,RCAN1,E2F5,TMEM35A,EPB41,MRPL10,ACSL4,ARHGAP36,KCNK3,KIT,MID1,MPP2,JAKMIP1,PKIA,FIGN,SYT1,OBSL1,SLC44A1,MGAT5B,SLC38A1" Coexpression M2867 Genes up-regulated in epithelial lung cancer cell lines upon over-expression of an oncogenic form of KRAS [Gene ID=3845] gene and knockdown of TBK1 [Gene ID=29110] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 6.75E-04 1.00E+00 1.01E-02 1.01E-01 51 290 "ABR,C3orf14,SRPX,RGS20,BID,RAB29,CAMK2G,CHGB,TMEM184B,IQCK,TBPL1,CREM,VCAN,ZFYVE16,RHOBTB1,SACS,DMTF1,DNAJB6,ENO2,GPHN,EXTL2,FERMT2,PCLO,FAM69A,NFYA,OCRL,SNX10,LRP12,SCHIP1,EPB41L4B,MINDY2,PPP3CC,TMEM104,PID1,RGS3,DCUN1D2,GALNT10,CHD9,SNCA,TEX2,PEG10,MTCL1,TIMP4,BEX4,TP53BP2,TUBB2A,RNF103,TUBA1A,CIAPIN1,PHTF2,NETO2" Coexpression M7105 Genes up-regulated in CD4 [GeneID=920] T cells treated with halofuginone [PubChem=400772]: 3h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 6.91E-04 1.00E+00 1.01E-02 1.01E-01 33 166 "MTA3,TAOK1,SFMBT2,INSYN2B,TMEM108,BBS2,SLC16A4,CLTB,ABCG1,CENPL,MAML1,ARMCX2,ZC3H11A,PTK2B,TAOK3,FECH,TRAF3IP2,GSN,L1CAM,MATK,MITF,MX1,P2RX7,PDE1B,PLEC,MTMR10,RNASEL,RXRA,SEMA6D,SEC31A,KDM4B,TSC1,ITM2C" Coexpression M365 Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 6.91E-04 1.00E+00 1.01E-02 1.01E-01 33 166 "HACE1,PDZD4,MADD,ARNTL,DPY19L3,CFLAR,SCAPER,GIT2,PDCD6IP,MBNL2,KMT5B,PLEKHA1,EZH1,PDLIM5,ERGIC3,FAM120B,RAPGEF6,SYNPO,MBNL1,P2RX7,MINDY2,PPP2R5E,PRKACB,PTPRE,CEP97,RFX3,SUPT20H,FAM102A,CHD9,WBP2,RNF103,PARP11,ZDHHC20" Coexpression M12707 "Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin, FN1 [GeneID=2335]." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.95E-04 1.00E+00 1.01E-02 1.01E-01 82 518 "BEND6,PKP4,APC,RGS20,DOCK11,NAE1,CCNH,SEPT7,DCLK1,CFL2,SRSF11,QKI,PCYT1B,CLOCK,NCOR1,CSNK1G3,UBXN2A,MATR3,YTHDC1,MYEF2,DTNA,DNM1L,EDN3,YAF2,MBNL2,EIF4G2,ACSL4,VTI1B,MSANTD4,KIAA1841,TUBGCP4,HTATSF1,STON1,ATE1,AP4S1,PSIP1,AGFG1,SMAP1,IFI16,INPP1,KIF2A,LIMS1,MBNL1,MYO5A,OPA1,OLA1,PIK3C2A,PPP3CA,OXR1,RBBP8,PBRM1,TMLHE,RPS20,SCP2,TRA2B,FNDC3A,GKAP1,MAPKBP1,RBM34,IQSEC2,TROVE2,ERBIN,NXT2,VPS13A,TAF9,AGTPBP1,TCEA1,TCF12,ITGB3BP,ACTR6,BHLHB9,R3HDM1,C9orf85,PDSS1,TBC1D15,XPO1,ZNF24,MFF,MRPL47,HNRNPA3,RSPRY1,FXR1" Coexpression M8553 Genes down-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ALCAM,AMPD3,MADD,CDC25B,ENTPD4,PITPNC1,GUCD1,RHOBTB1,CD99L2,PRKAG2,UBE2E3,TMEM107,STAU2,FYN,ZNF274,GSN,PADI2,DDX19B,LIFR,SYTL4,GPR155,MBD1,ZNF862,NUCB2,DIRAS2,ERI2,HES6,GKAP1,MPRIP,CAMTA1,ZMAT3,SLC44A1,THRA,KLC2,SLC38A1,TUBA1A,URM1,KLHDC1" Coexpression M5585 Genes down-regulated in comparison of central memory CD4 [GeneID=920] T cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ATP1A3,BTK,LDB2,CD38,FBXO7,MAGED1,CRY2,RNF14,AATK,CSF1R,ZNF804A,ELMO1,ACOT8,DNAJB6,TLR7,ADGRV1,CHST15,RASL10A,GABRG2,ADGRA3,GSN,IRF8,TM6SF1,MKLN1,PTPRE,ZDHHC4,RGS3,NUDT11,DGLUCY,GALNT10,ARHGAP26,KLHL4,USP22,NPL,TST,LAT2,ZNF74,ZNF142" Coexpression M5073 Genes down-regulated in comparison of memory CD8 T cells versus naive CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SORCS2,BACH1,CCPG1,MAP4K4,CNN3,CSNK1E,APPL1,DAPK1,ARMCX4,PITPNC1,ARMCX2,EGR3,SRRM1,TMEM164,SESN1,GSN,ZHX1,LIG4,PPM1L,FXYD7,RETREG2,BEND5,PCMTD2,ADAL,AP1AR,FNIP1,SCAF8,MYO18A,SMARCC2,KIF13A,ZHX3,RBM26,CLASP2,TCF4,KIAA0930,AKTIP,TSC1,UCHL1" Coexpression M3198 Genes up-regulated in comparison of naive B cell versus pre-germinal tonsil B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ARRB2,MARCH3,PTCH2,RAB29,DDR1,EPS15L1,FBXO7,PITPNM3,PUM1,FEM1B,USPL1,PTK2B,FCGR1A,FGF1,TRMO,SARAF,RUNDC3A,SYNPO,HMGCR,MAN2A2,MBP,NELL2,NME4,FXYD1,ING3,PPP3CA,PRODH,TUG1,RGS4,ZNF532,ZNF331,SAMSN1,PDLIM2,WBP2,TTTY15,ZNF154,TUBA1A,MPPE1" Coexpression M6671 Genes down-regulated in bone marrow-derived macrophagesat 180 min of stimulation by IL10 [GeneID=3486] and LPS: IL6 [GeneID=3469] knockout versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ACTN1,ABCD2,ALK,MTMR7,SIPA1L1,PDE4DIP,CNTNAP2,DGKG,DMTF1,MAMLD1,EDIL3,C8orf37,USPL1,ENPP6,GALNT15,GFRA2,FICD,MAP4K5,RASSF8,HSPA1L,ITGAM,MEF2C,LAYN,SH3KBP1,APTX,PTK2,DPF2,MAP6D1,FNDC3A,LGI3,MCF2L,THRA,TCEAL7,AMZ1,TMEM198,SPIRE1,SLC30A4,ST7" Coexpression M6096 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL-12 (6h). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ACTN1,APAF1,MADD,GPR146,SLC25A14,SPAG9,COL9A3,KIAA0040,GIT2,ZC3H11A,RASGRP1,EGR3,SEC23B,C2orf88,SARAF,INPP5K,GPR162,CNTRL,SYNPO,IRF8,IL6ST,INPP1,MATK,AFF1,PDE4B,PDE1B,SNRK,FAM102A,FAM126B,MYCBP2,SULF2,PJA1,SLC44A1,C9orf85,WIPF1,TUBA1A,MPPE1,DOCK8" Coexpression M4504 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "LTBP4,BIN1,LRBA,CDC25B,PLEKHB1,RAB33A,MAGED1,LRIG1,FAM169A,GPRASP1,SNPH,SPOCK2,KLHL3,PLEKHA1,ENO2,SH3YL1,SESN1,BACH2,HSF2,NELL2,NUCB2,PDE4D,PIK3R1,RETREG1,LRRN3,PKIA,ZNF331,FAM102A,HKDC1,MPRIP,SYNE2,DNAJC9,PJA1,MCF2L,DOCK9,AKTIP,SLC38A1,ITM2C" Coexpression M4884 Genes up-regulated in comparison of naive follicular B cells versus early germinal center (GC) B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "APC,DNAH17,RAB26,NCOR2,ARHGEF10,PDE4DIP,CYBB,B3GAT3,ZC3H11A,DPP6,E2F5,EBF1,SNX29,KAT8,ANKFY1,ZMAT1,TNRC6A,ZNF638,KIAA1958,HTATSF1,GP1BB,DHX35,LAMA2,NFE2L2,PDCD2,PIK3R1,ZNF655,MINDY2,PTPRN,MARCH1,PID1,SAFB,SCAF8,MBD5,MYCBP2,CDH22,KLC2,ELFN1" Coexpression M8504 Genes down-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ACTN1,NDRG3,NDRG2,ADCY6,ADRB2,KCNAB2,SFMBT2,CASK,ENTPD6,ABCG2,MAP4K4,CNN3,CD99L2,ABCC5,RASGRP2,SLC9B2,CINP,GGT5,IL6R,IL6ST,SETD4,PDE4B,SERPINI1,PLEC,POLG,RASA3,SCAF8,SGK1,ST8SIA1,SPTAN1,NACC2,LRRC8A,SSBP2,TUBB2A,EIF4ENIF1,VSNL1,SLC30A4,TUBA1A" Coexpression M7839 Genes up-regulated in resting T reg versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SYS1,BIN1,FGD2,TNRC6C,MADD,ARRB1,CCPG1,KIAA0040,MYADM,RIPOR2,SLC12A6,ARRDC4,RASGRP1,FRY,PHF20L1,MRVI1,TRAF3IP2,SESN1,DCLK2,PADI2,NUCB2,OXR1,CCDC82,EMID1,FAM102A,SLA,WDR47,MTERF2,CPEB4,ARHGAP26,SYNE2,VPS13A,DNMBP,ZEB1,FRYL,CYB561A3,MTMR14,JMJD1C" Coexpression M7016 Genes down-regulated in lymphoid-primed multipotent progenitors versus pro-B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SYS1,RNF157,TXNDC16,SFMBT2,NCOA1,GPR146,RAB29,AKAP12,RNF14,CS,GPSM1,CHRDL1,VPS26C,FGF11,ATP2C1,TRAF3IP2,STARD3,JAK2,KIF2A,TTYH2,PDE4B,OXR1,NCBP3,PUF60,SGK1,FAM102A,DZIP1,FAM214B,ZFP1,ARC,CD27-AS1,R3HDM1,C9orf85,ZNF346,PDSS1,AMACR,FTSJ1,FRMD6" Coexpression M9216 Genes up-regulated in CD8 T cells treated by inteferon alpha: wildtype versus STAT4 [GeneID=6775] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ACTN1,ADD1,ESYT2,ADRB2,TBC1D14,PHYHD1,CDC14B,NUMB,N4BP2L1,GPR146,CFLAR,KYAT1,CACNA2D2,ANKRD44,RGS6,PDE4DIP,ERC2,WDR20,RASGRP1,CALCRL,TRMO,CELF1,SARAF,TRAF3IP2,ACSS1,BACH2,IL6ST,FAM69A,MBP,MITF,SETD4,ZNF655,RASGRF2,RASA3,SGK1,PEX26,NACC2,LRRC24" Coexpression M6606 Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL6 [GeneID=3569] and LPS (45 min). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "LCORL,BACH1,CD86,CDC25B,RCBTB2,ARHGAP22,MAGED1,ENTPD4,OSBPL3,PHF14,FRY,RASA4,VPS26C,PTK2B,SESN1,KHK,STMN1,LMO2,RTL5,PIK3C2A,PRIMPOL,TUG1,PBRM1,AMBRA1,SLC11A1,SLC12A2,ABTB1,GLT8D1,CLASP2,SAMSN1,TAL1,TBCEL,DMXL2,ZFP90,MTMR14,TRPS1,HPS4,FXR1" Coexpression M4118 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "MTA3,AP2A2,TXNDC16,NCOA1,ADAM23,NFS1,CNTFR,MAGED1,ANKRD44,CS,DBI,MYEF2,CALCRL,FCGRT,MAD2L2,GSTT2,BACH2,HLF,LAMP2,MBP,MXI1,ETFRF1,PDE4B,ENPP2,GNG2,PRKCB,SNRK,C1orf54,LRRK2,MRAS,ST6GAL1,FNBP1,SLC37A2,MMS19,PRRT1,AMACR,TTC3,ZFAND5" Coexpression M8486 Genes down-regulated in B16 melanoma (day 3): untreated versus adoptive transfer therapy. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "BCAS1,MADD,BACH1,DDR1,B4GALT6,CSF1R,PDE4DIP,NR1D2,NCALD,IGSF6,ZMAT1,B4GALNT1,SESN1,GSN,FRMD5,ACOT7,IL6R,L1CAM,SMAD1,GPR155,MAN2A2,AFDN,SERPINI1,PRKCB,PTCH1,PTPRO,RGS3,RGS12,RNASEL,RTN1,CCDC112,CHD9,SLC12A2,MYCBP2,SLC44A1,SPIRE1,EVI5,JMJD1C" Coexpression M7992 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ZNF608,MAP4K3,CADPS,STX16,CNOT8,FAM171B,ARHGEF4,GIT2,ZC3H11A,RASA4,TLR7,PRKAG2,FOXO3,TMEM8B,INPP5K,SPIN1,STARD3,TPPP,PADI2,FAM69A,MATN2,MBNL1,RTL5,P2RY13,PTK2,TMEM231,PCMTD2,AMBRA1,RCOR3,ZSWIM8,ERBIN,TCF12,LMF1,P2RY12,WRN,SIGLEC10,RGS7BP,DOCK8" Coexpression M4299 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] high T cells at. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ACTN1,SPARCL1,PTCH2,TMEM108,AZGP1,LDLRAD4,LURAP1,ARHGEF25,FAM19A5,AKAP6,SLC35F1,ZC3H11A,SLC29A4,EGFR,TENM1,EPHB1,SCML2,CORO2B,FCGR3A,C2orf88,ADAM28,GPR12,KCND2,MAP6,LYPLAL1,MYO9A,NPY,PLCL1,SATB1,SLC14A1,CLSTN2,RHBDL3,SYP,TRIM2,PCDHB7,ZFPM2,TRIO,IFT88" Coexpression M7290 Genes up-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "TMCC3,ADD1,ADORA2A,SORCS2,BIN1,KCNAB2,PHYHD1,TMEFF1,ARRB1,NRP2,B4GALT6,CDC42BPB,CRMP1,SIPA1L1,MYADM,GUCD1,RHOBTB1,SLC29A4,FCGRT,AK8,ACSS1,TPPP,SPACA9,LRRC75A,RBPJ,LIFR,LMO2,AFDN,THYN1,NFIX,RFX2,MAPK12,RASA3,SGK1,ST6GAL1,SIRT2,STAC2,RGMB" Coexpression M8426 Genes up-regulated in pre-B cells: STAT5 knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "PLA2G4C,DNAH17,ATP2B2,ATP6V1G2,BMP7,KALRN,CAMK2G,SCARB1,DLGAP2,MAP4K4,PDE4DIP,CNTNAP2,SLITRK5,IGSF6,ADGRV1,AKAP3,B4GALNT1,GPR12,STON1,PADI2,KCNN1,KCNN3,L1CAM,LMO2,SMAD9,MX1,MYH3,NPTX1,NTRK3,P2RX7,CDK18,PGAM2,ZNF821,MCF2L,DOCK9,CRTC1,RIMBP2,PARD3" Coexpression M5719 Genes down-regulated in comparison of CTRLrv versus FOXP3rv (see Fig. 1 for details). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "AGT,INSYN2B,ALDH7A1,CFAP410,CAPN3,SH2B1,CSNK1G3,PPP1R16B,TMEM130,ZC3H11A,GPHN,F5,CHST15,SARAF,HHIPL1,GALNT15,HPGDS,ADAMTS6,MAP4K5,HLF,LRRCC1,IL6ST,HECTD2,LYPLAL1,RASGRF2,SMPD3,AMBRA1,SLC9A5,ABTB1,DBNDD2,CYB561A3,SLC44A1,TK2,TST,EVI5,ITM2C,ACTR3B,FRMD6" Coexpression M3771 Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADD1,KIF1A,BAIAP3,CAMK2G,AP4M1,LETMD1,ACOT8,DUSP9,ANKRD46,EPB41,ERBB2,F5,FCGR1A,FOXO3,DLL3,GLUL,GPR34,GRIK5,CIT,LINGO1,MAN1B1,HLF,L1CAM,MBP,LRP1B,SMIM11A,KCNIP3,HES6,IFT122,KIF13A,DBNDD2,ELOVL4,APOM,ITGB3BP,ERCC6L2,CELF4,EVI5,HRASLS" Coexpression M9363 Genes up-regulated in day 7 germinal center B cells versus day 40 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SFMBT2,CA12,CAMK2B,CAMK2G,USP2,GAL3ST1,NECTIN3,LRIG1,YAF2,VPS26C,DNAJC27,RACK1,ST3GAL6,GTF2IRD2,FGF13,MEX3B,KCNMB4,ELOVL5,AGFG1,MN1,NINJ2,DUSP26,VSTM2L,RNASEL,DCUN1D2,S100B,CCDC92,ATF7IP,INTS9,TBCEL,KLHL4,ARHGAP9,TIAM1,SSBP2,VLDLR,URM1,ZDHHC20,FRMD6" Coexpression M9258 Genes up-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5- BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADD1,AMPD3,GPR146,CCNT1,CFL2,CNN3,LRIG1,WDR20,NR1D2,RACK1,SUCO,FOXO3,IQGAP2,ACSS1,IRAK3,PADI2,BACH2,FAM69A,HECTD2,PPM1L,PDE4B,PFKFB2,PLCB2,MINDY2,PPM1B,PTK2,MCMBP,DZIP1,ST8SIA1,WDR37,SULF2,KIAA0930,RGMB,TRIO,TTC3,SGK3,PPP1R3F,MPPE1" Coexpression M7596 Genes up-regulated in CD11b+ from spleen of healthy C57BL6 versus CD11b+ cells from tumors of C57BL6 mice bearing EL4 lymphoma. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ABR,CLK4,ADRB2,OGT,N4BP2L1,CBFA2T2,ZNF337,MAML1,GIT2,ZC3H11A,USP3,ABCC5,IRAK4,ING4,MRNIP,EPB41,IP6K2,FOXO3,MSL3,BTN2A1,PSIP1,FAM69A,MXI1,LYRM9,NACA,CCSER2,ING3,PPP3CC,PTCH1,RPS20,SATB1,CASC3,MYCBP2,CLASP1,UBE2H,ZNF32,ZNF189,UPF3A" Coexpression M9925 Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 24h. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "FZD9,ATP1B3,BACH1,CCPG1,FAM171B,APPL1,RIPOR2,CENPL,LIN54,ARMCX4,PARD6A,MBNL2,RASGRP2,SUCO,MEX3B,PCYOX1,DOT1L,GLUL,IRF8,MSL1,KIT,STMN1,AFF1,SFR1,ZNF655,RASGEF1B,MSANTD2,KLHL11,MCMBP,FNIP1,SLC12A4,CPEB4,ZSWIM8,TEX2,KLHL7,MTMR14,TP53BP2,UBE2H" Coexpression M6888 Genes up-regulated in CD4 [GeneID=920] T cells with in vivo expansion: IL6 [GeneID=3569] versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADD1,AP2A2,ARNTL,ARRB1,LDB2,LRBA,CDH2,IP6K1,DMD,PCOLCE2,RASGRP2,EZH1,FCGRT,FHL1,FOXO3,SARAF,GSN,COQ10A,LAMA2,STMN1,SCAMP5,NPR2,PKD1,PTPRB,RXRA,SCP2,GALNT10,MYO18A,PEX26,LIMCH1,DNAJC9,CLASP1,SYNE1,ARHGAP9,ZMAT3,ZBTB14,PLD4,FAM13C" Coexpression M4344 Genes up-regulated in comparison of TregCD103+Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "AMPD3,DPP10,MAP4K3,BCAS1,FUBP1,AKAP5,ARHGEF10,PDE4DIP,PLXNC1,RGS17,F8,PRKAG2,HTATSF1,FUT10,ADAMTS6,GUCY1B1,RASSF8,SYNPO,KCNH2,MBP,MGAT3,NFIX,ZNF827,TMEM38A,MAPK9,SNRK,FAM102A,CPEB3,PDZRN3,STX1A,ARC,MCF2L,PCDHB15,FRYL,TIAM1,TRIO,TUBB2A,DHX33" Coexpression M6166 Genes up-regulated in D10.G4.1 T cell line (6h): control versus treated with NMU [GeneID=10874]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "DYNLL1,CNRIP1,CSNK1E,VCAN,PNPLA8,JAKMIP2,FBXL5,ZC3H11A,USP3,PDCD6IP,MAMLD1,PHC2,ACSL4,TAOK3,IP6K2,FLT1,ARFIP1,KLHL23,LAMP2,LIMS1,TM6SF1,PID1,EPHA10,ATP8B4,SLC11A1,KIF13A,FAM219A,NXT2,STAU1,STX1A,PJA1,CAMTA1,ERCC6L2,TMPO,TRIO,TRPS1,LAT2,LINC02210" Coexpression M9169 Genes up-regulated in CD4 [GeneID=920] T conv over-expressing: IKZF4 and LEF1 [GeneID=64375;52276] versus GATA1 and SATB1 [GeneID=6304] versus GATA1 and SATB1 [GeneID=6304;2623]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ABHD6,CC2D2A,ARHGAP20,C6orf89,BBS2,CFAP410,CA8,CACNA1A,CAST,HIP1R,CD86,CLIP3,LRIG1,GREB1,DCAF8,CD99L2,ENO2,GPHN,NRN1,FOXO3,EFCAB2,RBPJ,RTL5,ZNF862,PLCL1,SMOX,PURG,GTDC1,FAM214B,SLC12A4,ABTB1,MCF2L,DNAH7,TIAM1,WBP2,TOM1L2,NDRG4,PHTF2" Coexpression M9761 Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: follicular helper (Tfh) versus Ly6c int CXCR5+ [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADRA1B,DPP10,ASPA,ADGRB3,BMPR1B,SGCE,SCARB1,ARHGAP33,ERC2,DCAF4,DPH1,MTSS1L,TMEM132C,PRAM1,APOPT1,AIFM3,MAN1B1,IPO5,PACRG,MEF2C,BLOC1S2,NDP,P2RY1,SCHIP1,KANSL1,PKIA,MAPK10,GDPD1,WBP1L,CCDC112,SEC31A,SNAP25,SPTAN1,IQCE,CADM2,SEMA3B,SIGLEC10,KCNAB1" Coexpression M5324 Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 72 h versus those from old donors treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "CLK4,SPOP,STX16,N4BP2L1,SYNJ1,FOXN3,CSF1,CSF2RA,MAML1,GSDME,FAM13A,SUGP2,AASS,PLEKHA1,ING4,SARAF,FYB1,NFU1,HLF,RBPJ,MXI1,NELL2,CNOT4,SLC11A2,OGG1,TREM2,PDCD2,ZFYVE21,PRKCB,BCAS3,PTCH1,ZSCAN32,PCMTD2,TRAPPC13,ATXN2,ST8SIA1,TIAM1,ZNF37BP" Coexpression M9420 Genes up-regulated in DN3 thymocytes: wildtype versus TCF7 [GeneID=6932] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "APBB2,GAS7,ADAM23,ST3GAL5,MTMR3,WASF1,CD38,MAGI1,RNF14,ABCG1,RGS6,CSNK1E,ARHGAP32,RIPOR2,DAPK1,RHOBTB1,OPTN,EIF1,CHST15,IQGAP2,RASSF8,AGFG1,SMAD1,MXI1,ZNF862,NPTX1,PRKCB,PTPRE,RPS6KA2,BTBD3,SNAP25,KDM4C,DNMBP,IQCE,DOCK9,GORASP1,ZNF32,EVI5" Coexpression M7186 Genes down-regulated in transitional CR2 [GeneID=1380] high B lymphocytes versus those from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADD1,SFMBT2,MADD,ARNTL,MTMR3,CBR1,FAM189A2,AKAP12,GUCD1,DOCK2,SLC12A6,HVCN1,FYN,GGT7,KCNMB4,PSIP1,ADAMTS6,IL6ST,INPP5B,KCNH2,IDNK,SMOX,POU6F1,CEP97,OXR1,GTDC1,CCDC82,RASA3,STX1A,RHBDL3,KIAA1107,TBCEL,LRRC8A,RUNDC3B,MEIS3,PCBP4,ADAMTS10,FRMD6" Coexpression M5049 Genes up-regulated in comparison of splenic secondary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SYN3,ACADM,AS3MT,TNRC6C,CDC14B,DPY19L3,NRP2,LDLRAD4,CBR1,ARHGEF2,IP6K1,PITPNC1,USP3,NR1D2,TSPAN5,RASGRP1,FRY,NCALD,FCGRT,SARAF,GABBR1,IQGAP2,ACSS1,GABARAPL2,PRKAB2,RXRA,GALNT10,SGK1,PEX26,FNBP1,DBNDD2,STX1A,SULF2,GPRIN3,LRRC8A,TP53BP2,MEIS3,ADAMTS9" Coexpression M5220 Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ABCD2,AMT,ASGR1,PROM1,CAMK2A,CAMK2B,SLC25A14,CBS,FOXN3,COL4A5,COL9A3,C2CD2,ABCG1,CRYM,CSNK1E,IP6K1,SUGP2,REEP2,SH3YL1,SEMA4D,FOLH1,KAT7,GUCY1B1,KTN1,MATN2,ADAM11,NACA,PKD1,PMP22,PTH1R,EXD2,SEC31A,USP22,TIAM1,TP53BP1,TRIO,UPF3A,PCBP4" Coexpression M9310 Genes down-regulated in follicular B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "CADPS,DYNLL1,ARHGEF7,SCARB1,FBXO7,GAL3ST1,CSF2RA,CST3,KIAA0040,GIT2,DLX1,EPB41,TLR7,GMPR2,TAOK3,TCERG1,ADAP1,AP4S1,SLC2A6,HMGCL,ICA1,IDH3B,STXBP5,NFYA,NINJ2,TREM2,GPSM2,POLR2F,PTPRO,ZSCAN2,CCDC82,MCMBP,HES6,TRIM67,MTMR14,PIK3R5,LAT2,ATP6V0E2" Coexpression M4667 Genes down-regulated in comparison of untreated CD8 T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ZNF608,TBC1D14,C1QTNF1,FAM135A,NCOA1,CH25H,CDO1,LY86,MAGED1,RIPOR2,ARHGAP24,RHOBTB1,MED12,EBF1,KCTD3,GTF2IRD2,SARAF,FAM120B,SRCAP,USP19,PRDM5,PSIP1,MAN1B1,MBP,POC1B,FXYD7,PKD1,PRKAB2,PRKACB,PRKCB,QRICH1,EML5,ROGDI,LRRK2,SH3BP2,SLC4A3,ATF7IP,ZNF708" Coexpression M6269 Genes up-regulated in medullary thymic epithelial cells (mTEC) with AIRE [GeneID=326] knockout: CD80 [GeneID=941] high versus low. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ABR,NCKAP5,SEMA7A,SGCE,CH25H,SRSF11,ASIC3,RAB33A,MAGED1,VCAN,MYADM,BRINP1,NRN1,ABCA8,PPP1R1B,OLFM1,SUCO,ATP13A4,AKAP3,CGREF1,FYB1,PLCD4,IRAK3,SCIN,IL12A,KCNF1,MXI1,PLTP,PILRA,ROGDI,ENOX1,ATP8B4,SLA,SLC4A3,SNCA,TIAM1,TMEM178A,PCBP4" Coexpression M9608 Genes up-regulated in CD42 low [GeneID=100133941] cells from thymus: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SPARCL1,ADGRB1,MAP4K4,HOMER3,GPSM1,DBT,PITPNC1,YTHDC1,RCAN1,AGAP3,CINP,SMC2,TUBGCP4,SRCAP,GFER,GP1BB,CLASRP,GSTM5,LSS,CLDN11,PALM,ENPP2,MAPK7,SNRK,ELP2,RPS6KA2,KIF16B,FHOD3,DBNDD2,KLHL7,JMJD6,SYPL1,TACR1,NSD1,DICER1,VAV1,LAT2,WRN" Coexpression M8206 Genes down-regulated in macrophages: tumoricidal versus control. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADCY6,AMPD3,SEMA7A,PPFIA4,KIF1A,MYRF,CRMP1,CSF1R,CSF2RA,GPRASP1,DBN1,FCF1,RASA4,CLVS1,OLFM1,FGFR3,EVL,TPPP3,MTHFD2,ACSS1,ZNF276,STARD3,GPD2,PADI2,INPP5B,KIT,GNG2,SEMA5B,PKM,MAGEL2,CYBC1,ZFHX4,RTN1,ST6GAL1,FNBP1,NEK4,SULF2,NDRG4" Coexpression M8306 Genes down-regulated in activated T cells: CD4 [GeneID=920] versus Va24- NKT. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "CALM1,CDC25B,FOXN3,TPP1,RBM39,PPP6R2,SPOCK2,SGSM2,DNAJB6,EIF4G2,EIF5,TENM1,TNK2,EIF1,VPS13B,RASGRP2,SH3YL1,ST3GAL6,SARAF,FYB1,SRCAP,KAT7,ITPKB,MBNL1,NUCB2,PAX6,PDE4B,PDE4D,SNRK,PCMTD2,SYNE2,MCF2L,SYNE1,TSN,TUBB2A,TUBA1A,CIAPIN1,MPPE1" Coexpression M6447 Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B1 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "OGT,TNRC6C,CDK13,MARCH3,STX16,DOCK11,SYNJ1,CCPG1,CNOT8,C4orf33,RCHY1,TBPL1,TIAM2,VPS13B,MPP6,GAD1,RAPGEF6,ZNF274,GCNT2,GFRA2,ZNF638,DIDO1,MIER3,BLOC1S2,MYO9A,ABCB1,PURG,PPM1B,PTPRE,CLIP1,DOP1A,ZBTB43,ANKRD12,KIAA0930,NR2C2,MFF,DPF3,RNF146" Coexpression M7515 Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "FMNL2,FGD2,MYOM1,CBFA2T2,LY86,ELMO1,TMCC2,DOCK2,CALCRL,RASGRP2,EXTL2,IQGAP2,INPP5K,SESN1,GHR,PADI2,NCKAP1L,IRF8,NIM1K,STMN1,SMAD1,TM6SF1,MEIS1,MITF,PDE4B,SLC25A23,SH3KBP1,C1orf54,SPP1,CEP68,MCF2L,TLR4,AMZ1,PCBP4,DOCK8,FRMD6,IFT88,SPATA13" Coexpression M6035 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus IL4 [GeneID=3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "METAP1D,TNRC6C,CDK10,ARRB1,DNAH17,ZBTB10,SPAG9,EVI5L,STOML1,ZFP28,CNRIP1,ANKRD44,IPCEF1,IP6K1,SLC29A4,SLC12A6,PLXNC1,FCGRT,RBPJ,IL6R,PAXBP1,KCTD6,NUCB2,SETD4,PDE1B,PLEC,TATDN3,PPP3CA,RASGEF1B,RIPOR1,C1orf54,SH3BP2,AMBRA1,TCF4,CYB561A3,TK2,TOM1L2,MEIS3" Coexpression M3222 Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells activated with lamina propria dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ARRB2,BCS1L,PROM1,RCBTB2,MAP4K4,HAPLN1,CRYBB1,OSBPL3,GALNT9,PPP6R2,GUCD1,CDKL3,EZH1,FCGRT,ATP13A4,MSL3,BVES,ATXN2L,ARHGAP36,SOWAHA,INPP1,SLC35G1,CDH20,STXBP5,PIK3AP1,NTRK3,PLTP,HYDIN,GDPD1,LRFN5,ST8SIA1,LHPP,SYNE1,TSN,KCNT2,LYPD6,CELF4,SLC38A1" Coexpression M9408 Genes down-regulated in CD8A [GeneID=935] dendritic cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "RALGAPA1,ACTN1,AMPD2,MAP4K4,AKAP12,LRIG1,ZFYVE16,ARMCX2,ST3GAL6,CHST15,FOXO3,FYN,TRAF3IP2,IQGAP2,STARD3,LILRA2,GSN,GUCY1A1,LMO2,SMAD1,MEF2C,AFF1,MXI1,NFYA,PDE4B,SERPINI1,RETREG1,PPP3CC,PTPRE,PCMTD2,SATB1,SLC2A5,TMCC1,RGL1,DMXL2,BEX4,VAV1,ATP6V0E2" Coexpression M3605 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADORA1,ADRB2,MAP4K3,APC,TMEFF1,SEC11C,CCK,USP2,CLTB,AKAP7,CRY2,ABCG1,DLX1,NR1D2,E2F5,ERCC2,TLR7,UBE2E3,USP21,NEURL4,CNTRL,PRDM5,IDH3A,INSM1,KITLG,MX1,NFIX,PKD1,RETREG2,PRPSAP2,RASGRF2,RPS6KA2,GALNT10,SLC6A8,ST5,JMJD6,AMACR,ST7" Coexpression M7132 Genes up-regulated in peripheral blood monocytes (PMBC): Gram positive sepsis versus mixed infection sepsis. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ABR,TBC1D14,MAP4K3,PKP4,BTK,MAGED1,PITPNC1,CASP8AP2,EEF1D,VPS26C,GFER,PSIP1,HMGCL,IRF8,IL6R,SMAD1,MOV10,PTOV1,NTRK2,STRN3,AP1AR,ATXN2,FOXRED1,SCAF8,ST6GAL1,CMTR2,MYCBP2,DBNDD2,RBM26,SPART,RGL1,PJA1,TCF4,TCF12,METTL3,VAV1,INTS3,MFF" Coexpression M7207 Genes up-regulated in tumors established by injecting MC38 cells (colon cancer): control versus CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ADCY6,ADD1,SORCS2,CARNS1,PPFIA4,TNRC6C,MADD,CAMK2G,RHBDL1,ENTPD6,RCBTB2,COL9A3,VCAN,GUCD1,SEC16A,TOM1,EIF4G1,RASGRP2,NOP56,ZNF605,GAA,SESN1,ADAM28,GGT5,GIT1,PTOV1,PLEC,STK32B,GALNT10,RASA3,SLC6A8,SNCA,PBLD,PCDHB7,NACC2,TTC3,SLC35A4,ZNF23" Coexpression M4312 Genes down-regulated in comparison of TregCD103-Klrg1 versus TconvLP (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "ALDH7A1,BLM,FAM171B,CSNK1E,PLCXD3,RASSF2,PITPNC1,EDNRA,RASGRP2,EZH1,ACSS1,GPD2,IL6R,FAM69A,CDH20,MGAT3,MYO6,NFE2L2,NME4,ABCB1,TMIE,SMOX,LRP12,CCDC82,ATP8B4,DZIP1,ANKRD6,MYCBP2,KLHL7,CUX2,PHF24,NACC2,SMUG1,TTC3,SGK3,VSNL1,RNF170,KLHDC1" Coexpression M3156 Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "SYS1,AMPD3,PARG,ZFYVE28,CAMK2B,SEPT7,CDO1,VCAN,ZFYVE16,ASB3,EVL,TUBGCP4,KIAA1958,CNTRL,PSIP1,MAN1B1,FAM69A,GATD1,MARK3,MEST,AFF1,CCSER2,SLC26A11,GRAMD1C,ANKHD1,PBRM1,RNASEL,FAM102A,EPC1,TMCC1,MPRIP,SMG6,MGRN1,UBE2H,WIPF1,ZNF708,RSPRY1,SENP7" Coexpression M2720 Genes up-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH). MSigDB C6: Oncogenic Signatures (v6.0) 7.15E-04 1.00E+00 1.01E-02 1.01E-01 38 200 "NDRG2,SPOP,ATP1A1,SCARB1,AKAP6,LETMD1,MAGED1,RCHY1,ZNF385A,CLOCK,CS,PDE4DIP,KIAA0040,EARS2,IST1,ELMO1,ELN,ACSL4,STRADA,UFM1,MTHFD2,LIMS1,KANSL1,CEP41,MRPS18A,DGLUCY,COPZ1,KANSL3,CPEB4,TRIM2,TMEM9,CHST5,HSPBP1,SLC35A4,TBC1D15,POLR3H,URM1,AAAS" Coexpression M7725 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 7.16E-04 1.00E+00 1.01E-02 1.01E-01 34 173 "FMNL2,RNF157,SEMA7A,TMEM184B,CNN3,PPP1R16B,C2CD2L,RASGRP1,MBNL2,PAN3,SEMA4D,DOT1L,AHDC1,DCLK2,MAP4K5,AGBL5,ITPKB,LIG4,MATN2,MBNL1,XRRA1,MMP17,NTRK3,PDPK1,PFKFB3,FAM161B,SLA,MPRIP,ADAMTS17,SLC37A2,ZEB1,PRRT1,PIK3R5,PARP11" Coexpression M1204 Cluster 8: genes showing sustained pattern of down-regulation after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.20E-04 1.00E+00 1.02E-02 1.01E-01 5 8 "KIAA0753,MAPT,NRCAM,SERPINI1,SPP1" Coexpression M78 "Genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.27E-04 1.00E+00 1.03E-02 1.02E-01 39 207 "ACHE,BIN1,AQP6,MYOM1,CAMK2B,TAOK2,MYL6B,QKI,ARHGEF6,PDE4DIP,FAM131B,RUSC2,C2CD2L,DMPK,FAM13A,ING4,CALCRL,FER,FHL1,PDLIM5,FYB1,GNAO1,ADAP1,GPR37,MEF2C,MYH3,MAPK7,MAPK10,MRAS,ABLIM3,SLC12A2,CLSTN2,SST,TNS1,TPM1,TTC3,LAT2,XRCC4,REEP1" Coexpression M5659 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 7.41E-04 1.00E+00 1.05E-02 1.04E-01 32 160 "APOC1,MARCH3,ATP6V1G2,ADAM23,SYNJ2,LDB2,SEPT7,STOML1,MAGED1,PUM1,KLHL3,SNX29,TENM1,EXTL2,SEPT9,IL6ST,FAM69A,PCDH9,ENPP2,RETREG1,LRRN3,PKIA,APTX,SUSD4,GAL3ST4,ROBO1,FAM102A,LIMS2,MAPKBP1,VPS13A,MTCL1,SMIM8" Coexpression M7005 Genes up-regulated in hematopoietic stem cells versus megakaryo-erythrocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 7.41E-04 1.00E+00 1.05E-02 1.04E-01 32 160 "ACTN1,ADCY6,CARNS1,ABCG1,LRIG1,IPCEF1,RASGRP1,PLEKHA1,CHST15,EVL,RAPGEF6,SESN1,TDRKH,BACH2,IL6ST,SLC11A2,EXOSC10,EML5,BEND5,RIC8B,AP1AR,ST6GAL1,DZIP1,ST8SIA1,SLC14A1,TET1,EPC1,MGRN1,ZEB1,SSBP2,TTC3,TOM1L2" Coexpression 18172295-SuppTable2 Human Bone_Heller08_324genes GeneSigDB 7.53E-04 1.00E+00 1.06E-02 1.05E-01 47 263 "APLP1,CDK10,TMEFF1,ADAM15,CACNA1G,WASF1,BAIAP3,SPAG9,CLTC,SLC4A8,AKAP12,PDE4DIP,DAPK3,DBN1,SEZ6L2,AASS,CDKL3,TAOK3,FER,FHL1,CGREF1,CYP46A1,STARD3,GSN,HBA1,MAN1B1,ITGA7,KHK,L1CAM,MEF2C,ENPP2,SERPINI1,GPSM2,PRPH,NUDT11,SBF1,SH3GL3,PPM1E,ANKRD6,SLC6A8,SMARCD3,ZSWIM8,PEG10,CAMTA1,DOCK9,TST,SLC17A7" Coexpression M10952 "Genes up-regulated in the atria of healthy hearts, compared to venticles." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.56E-04 1.00E+00 1.06E-02 1.05E-01 45 249 "ACTN1,ADORA1,CADPS,CDK13,PDE8B,SGCE,CACNA1B,DDR1,CDO1,CACNA2D2,CHGB,RAB33A,MAGED1,VCAN,GPRASP1,CHRDL1,EDNRA,TNK2,ENO2,ERBB2,ERBB4,ERGIC3,CHL1,GABRB3,GNAO1,PRUNE2,GRIN2C,SYNPO,INPP1,KCNK3,PTOV1,SLC11A2,NTRK2,PDE4B,LRRN3,RELN,PTH1R,KCTD17,NMNAT2,UNC5B,PLCB1,TUBB2A,FLRT2,VSNL1,RTN4" Coexpression M6809 Genes up-regulated in B lymphocytes: expressing IgM BCR [GeneID=613] fusion and untreated versus expressing IgMG BCR [GeneID=613] fusion and treated by anti-HEL. MSigDB C7: Immunologic Signatures (v6.0) 7.58E-04 1.00E+00 1.06E-02 1.05E-01 36 187 "KLHL13,CDC42BPA,CDC14B,ATP6V0A1,BLM,CERS5,PPT2,CNTFR,PPP6R2,C2CD2L,MRPL37,FECH,PRKAG2,NBEA,POMT1,DBF4,CIT,FRMD3,SLC6A17,MAN2A2,MBP,POC1B,ING3,MAPK3,EPDR1,PRODH,ZDHHC4,KIRREL1,PREX2,PEG10,CBX5,SLC35A4,TOM1L2,SLC38A1,PCBP4,RNF170" Coexpression M4781 Down-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.59E-04 1.00E+00 1.06E-02 1.05E-01 28 134 "ESYT2,ZBTB10,EIF4G3,CREM,PNPLA8,ZBTB24,LINC-PINT,EIF5,EIF1,SUCO,SARAF,RAPGEF6,ATP2B1-AS1,OPA1,PDE4D,ING3,ZNF331,TRA2B,EPC1,KDM3A,TSPYL2,SIK3,TUBB2A,WIPF1,ZFAND5,RNF103,JMJD1C,TTC7A" Coexpression M17083 "Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the mature B" MSigDB C2: CGP Curated Gene Sets (v6.0) 7.59E-04 1.00E+00 1.06E-02 1.05E-01 21 90 "DGCR6,ADD1,ADRB2,TBC1D14,LY86,RIPOR2,YTHDC1,EBI3,B4GALNT1,IRF8,JAK2,MEF2C,POU6F1,RAP1GDS1,RMI1,RASA3,SH3BP2,FAM102A,MYCBP2,LAT2,PHTF2" Coexpression 18849563-SuppTable2 Human Lung_not_cancer_Bhattacharya09_65genes GeneSigDB 7.64E-04 1.00E+00 1.07E-02 1.06E-01 15 55 "RUNX1T1,SLIT2,QKI,ZNF44,KIT,KITLG,PTCH1,SEMA6D,TNFRSF19,SLC12A2,RBM26,ZNF302,HIF3A,PLEKHH2,ZNF30" Coexpression 17297478-SuppTable5 Human Intestine_Vecchi07_1024genes GeneSigDB 7.83E-04 1.00E+00 1.09E-02 1.08E-01 116 781 "ADRB2,INTS2,NME5,KIAA1324,SRPX,AMPH,ASPA,BARD1,BCHE,BID,BMPR1B,FUBP1,PRC1,CLDN10,CDC25B,LONRF2,CFL2,CHGB,SLIT2,CNTN1,MYRIP,PLCXD3,ARHGAP24,CENPL,MATR3,ARMCX2,CHRDL1,DMD,ARRDC4,DTNA,EBF1,RCAN2,LRRC17,RAB9B,ARMCX1,ABCA8,ST3GAL6,FHL1,NOP56,NELFCD,CSPG5,FUT9,GABBR1,GABRB3,GAD1,CPLX1,GCNT2,ADAM28,GHR,LYVE1,GLUL,MAP7D2,GNAO1,GPER1,FAM107A,UBE2QL1,HLF,IDH3B,IL6R,KCNJ5,KCNJ16,KIT,LAMA2,LIFR,GPR155,SAMD5,COMMD5,MT1M,NEXMIF,BEX5,ALDH1L2,SMIM11A,NTRK3,PCDH9,ENPP2,SERPINI1,GPSM2,PLIN1,PRKACB,KLK6,SPDL1,PID1,SUSD4,BEND5,FIGN,RGS4,PRIMA1,GSTCD,SCN7A,FERMT1,SLC6A8,SMARCA4,SNRPN,SPP1,SPTAN1,SPART,ATP10B,PBLD,SST,SSTR1,ERBIN,MCF2L,ADGRL3,TPCN2,TPM1,RGMB,SYNPO2,TRIO,PDSS1,VLDLR,CLDND1,XRCC4,PCDH20,ZIC2,ZFP41,STOX2" Coexpression 19185848-Table1 Mouse StemCell_Read09_41genes GeneSigDB 7.87E-04 1.00E+00 1.10E-02 1.09E-01 12 39 "SEMA6A,FBXO7,AIFM3,CELF5,L1CAM,NRCAM,SH3KBP1,MAPK10,CPEB4,GPRIN3,ZFPM2,CELF4" Coexpression 20077526-TableS3 Human StemCell_Hao09_612genes GeneSigDB 7.99E-04 1.00E+00 1.11E-02 1.10E-01 71 438 "CLK4,AXIN2,USP31,KIAA1211,TXNDC16,ZFYVE28,ARNTL,DST,RAB29,CALB2,DCLK1,RCBTB2,MAP4K4,COL9A3,NECTIN3,CPS1,VCAN,HDAC9,GSDME,EDNRA,FAM13A,EGFR,MBNL2,ERCC2,CDKL3,IP6K2,PCYOX1,PDLIM5,SRCAP,RAB40B,GRB10,PRDM5,GSN,GSTT2,CPT1C,ZIC5,IBA57,METTL21A,L1CAM,MAT2A,MEIS2,MID1,POC1B,MITF,SERPINI1,TMEM38A,KCTD15,PSAT1,OXR1,TCP11L1,RPS6KA2,SEC14L1,CHD9,SYBU,CPEB4,PEG10,CEP68,SULF2,KLHL7,SATB2,DOCK9,SLC44A1,TIAM1,TPM2,TOM1L2,VSNL1,XRCC4,NDRG4,FZD3,MSRB3,NETO2" Coexpression M6826 Genes down-regulated in monocytes: untreated versus anti- FcgRIIB. MSigDB C7: Immunologic Signatures (v6.0) 8.28E-04 1.00E+00 1.15E-02 1.14E-01 32 161 "OGT,CDC42BPA,TNRC6C,SCAPER,HAP1,LRRFIP1,EPS15L1,SLC4A8,NCOR1,PPP6R2,ZFYVE16,MTX3,DMTF1,AASDH,FRY,GPHN,NBEA,TNRC6A,DCLK2,CNTRL,STXBP5,MEIS2,PDE4A,POLG,PTPRD,CHD9,KDM3A,PHLDB1,TIAM1,R3HDM1,CABIN1,PRDM10" Coexpression M2827 Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL21 [Gene ID=59067]. MSigDB C6: Oncogenic Signatures (v6.0) 8.39E-04 1.00E+00 1.17E-02 1.16E-01 36 188 "SPARCL1,SEMA7A,BAIAP3,USP2,ARHGAP22,AATK,ARHGAP32,DGKG,OLFM1,AGAP2,IQCG,GABRB3,GDF9,GNAL,LILRB4,FAM107A,GUCY1B1,OPRL1,GPR85,FA2H,PTH1R,PTPRN,PTPRO,PTX3,NUDT11,SCN8A,FUZ,MYH15,SPP1,SPART,SST,ELOVL4,PCDHA5,UGT8,VSNL1,NDRG4" Coexpression M4674 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] effector memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.55E-04 1.00E+00 1.19E-02 1.18E-01 37 195 "CLK4,KLHL32,TMEM132B,RNF157,MARCH3,ZSCAN18,STX16,N4BP2L1,FUBP1,CDR1,RAB33A,BAG4,IPCEF1,KLHL3,TENM1,C8orf37,ARMCX1,SCML2,EVL,POLL,ZC3H12B,SLC11A2,EPB41L4B,LRRN3,ZIK1,C1orf109,KLHL11,PCMTD2,SATB1,CNKSR2,SEPHS1,ERC1,ZC4H2,RNF175,ZNF23,ZNF37BP,LAS1L" Coexpression M1873 Genes down-regulated in bone marrow progenitors by constitutively active NOTCH1 [GeneID=4851]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.66E-04 1.00E+00 1.20E-02 1.19E-01 8 20 "BTK,CSF1R,CSF2RA,LRRC25,ITGAM,MATK,NCF2,TREM2" Coexpression M17123 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing 11q23 rearrangements. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.73E-04 1.00E+00 1.21E-02 1.20E-01 59 351 "ABR,AK2,GAS7,N4BP2L1,ADAM23,ADAM15,BMP7,CAPN3,CAST,CARS,PPT2,QKI,PCYT1B,CS,LRIG1,FAM169A,CYBB,HDAC9,EXOG,TENM1,RASGRP2,FCGR1A,ST3GAL6,ATP5PD,SEMA4D,GLUL,CBX1,IDH3A,IL6R,ITGA7,KHK,SMAD1,MBNL1,SHC3,MEF2C,MEIS1,MMP17,MYO6,NFIX,PKM,PRKCB,MAPK9,RET,EMID1,GLT8D1,MCF2L2,CAMTA2,NEK4,SUPT5H,TACC1,TAL1,DMXL2,PCDHA3,VIPR2,CLDND1,EVI5,MPPE1,NELFE,JMJD1C" Coexpression M5793 Down-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.80E-04 1.00E+00 1.22E-02 1.21E-01 39 209 "AXIN2,OSBPL8,ATP6V0A1,CCPG1,FAM171B,CSF1,CST3,DNM1,DPYSL2,KLHL5,EGFR,ETV1,FAM198B,FCGRT,GABBR1,GATM,SESN1,PRUNE2,GSN,IRAK3,IL6ST,ITPKB,KIT,LSS,MBP,MXI1,XRN1,PLXNB1,WBP1L,REV3L,SLC25A36,ELP2,SATB1,PDZRN3,ANKRD12,ZMAT3,ZNF106,WBP2,RNF146" Coexpression 16397233-Table2 Mouse Liver_Ryschich06_100genes_DownRegulated GeneSigDB 8.85E-04 1.00E+00 1.22E-02 1.21E-01 21 91 "ADD1,LTBP4,ARRB1,PTCH2,NUMB,LDB2,MTSS1L,STX2,ATP2C1,ITPKB,MEIS1,MYO6,SEPT4,RPS6KA2,EPN2,STXBP1,PCDHGA11,TNS2,TEK,THRA,TIAM1" Coexpression 18280641-table2 Human Prostate_Sigala08_76genes GeneSigDB 8.89E-04 1.00E+00 1.23E-02 1.22E-01 18 73 "CLOCK,ABCG1,DCAF8,HSPA12B,AGAP3,RAPGEF6,DISC1,LMO2,PLEC,PPARA,EPN2,MBD5,FNBP1,SLC44A1,TMPO,TRIO,KCNT2,KLHDC1" Coexpression 18381423-SuppTable1a Human StemCell_Riggi08_262genes GeneSigDB 9.07E-04 1.00E+00 1.25E-02 1.24E-01 35 182 "BEND6,SRPX,CEP126,NRP2,CA12,PRC1,LRRFIP1,CLGN,ZNF521,VCAN,HEPH,NR1D2,ECM2,EBF1,EGFR,PCOLCE2,ETV1,SCARA3,GALNT15,GPER1,HAS2,HNMT,KITLG,MMP16,CLDN11,PDE4B,GNG2,GPSM2,PTN,RPS6KA2,TNFRSF19,FHOD3,SLC2A5,PDZRN3,PLCB1" Coexpression M3898 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.13E-04 1.00E+00 1.26E-02 1.25E-01 77 485 "ACADM,ADRB2,OGT,RGS20,ATP1B3,ATP2A2,ARHGEF7,NAE1,MTMR3,WASF1,USP6,ENTPD6,RCBTB2,SRSF11,CLTC,CNN3,CNTN1,ENTPD4,ARHGEF4,DCAF8,YTHDC1,GSDME,ABCC5,YAF2,SUGP2,RABEPK,VPS26C,SCML2,RACK1,FDFT1,SEC24B,BAIAP2,FOXO3,CAMKK2,ATP2C1,ERAP1,MALT1,BRD8,TCERG1,ZNF638,CBX1,ELOVL5,KIF2A,IPO5,KTN1,LAMP2,MAP4,MARK3,MBNL1,MIA2,AFF1,PTOV1,MYO5A,CNOT4,SLC11A2,STRN3,PPP2R5E,RBBP8,RDX,CLIP1,ATXN2,TRA2B,HSPA4L,TROVE2,STAU1,SYPL1,MMS19,TACC1,PUM2,TP53BP1,FLRT2,USP1,VSNL1,XPO1,ZFAND5,UPF3A,KAT6A" Coexpression M8129 Genes down-regulated in AGS cells (gastric adenocarcinoma): control versus H. pylori LPS. MSigDB C7: Immunologic Signatures (v6.0) 9.24E-04 1.00E+00 1.27E-02 1.26E-01 32 162 "CLK4,MTA3,OGT,SEMA7A,CCNT1,ENTPD4,RBM39,ING4,MALT1,TNRC6A,LILRB4,CNTRL,KTN1,MBNL1,MX1,PDE4D,PIK3C2A,PLCB2,TUG1,TRIM68,ZC3H14,ATXN7,PPP4R3A,ZKSCAN3,USP33,BDP1,MYCBP2,ERBIN,DOCK9,ARHGAP9,DICER1,RUNDC3B" Coexpression M8182 Genes down-regulated in B lymphocytes immunized with: imiquimod [PubChem=13982876] versus monophosphoryl lipid A and imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 9.24E-04 1.00E+00 1.27E-02 1.26E-01 32 162 "ADRB2,AK2,DPY19L3,BTK,RIPOR2,USP3,PAN3,POLR1B,WDR83,ATP6V1H,GABBR1,SESN1,DBF4,RAB30,GPD1,IRF8,TJAP1,JAK2,SH3KBP1,MARCH1,RAP1GDS1,EXD2,SATB1,TRA2B,SLA,GKAP1,SS18,ATMIN,USP22,SIRT1,SGK3,ZFAND5" Coexpression 17430594-table4 Human Prostate_Chandran07_154genes GeneSigDB 9.29E-04 1.00E+00 1.27E-02 1.26E-01 24 110 "PKP4,NCOA1,BMP7,MAP4K4,BOC,EGR3,FGF13,ZNF605,BRD8,LSAMP,AFDN,MN1,NBL1,NINJ2,CNTN3,PCDHGC3,PCDH18,PTN,RBBP6,ROBO2,HES6,SPP1,ZNF621,CLASP2" Coexpression 20460173-ImmPortCD40LandAnti-IgMvsControl Human Immune_Kong10_2491genes_ImmPort_CD40LandAnti-IgMvsControl GeneSigDB 9.32E-04 1.00E+00 1.28E-02 1.27E-01 216 1586 "ABR,KDM5D,ADD1,ADORA2A,MTUS1,AMH,SEMA7A,PKP4,APBB2,GAS7,APOC2,CASK,RGS20,CHRD,ATP6V0A1,BACH1,BARD1,BCL7A,BCS1L,BLM,CFLAR,BMP7,ARHGEF7,BTK,SGCE,CACNB4,CALM1,CAST,RUNX1T1,CBS,CD86,SCARB1,CD38,LRBA,ARHGEF2,CDC25B,CDH2,UBE2L6,COPB2,MYL6B,STOML1,SULT4A1,LY86,ARHGEF6,CNR1,LETMD1,MAGED1,COX4I1,CLOCK,CRY2,RNF14,ABCG1,CS,LRIG1,PDE4DIP,CST3,SLITRK5,KIAA0040,HDAC9,DCAF8,TBC1D5,SCRN1,IP6K1,GIT2,ARMCX2,ZNF804A,ELMO1,B3GAT3,GSDME,SV2B,DNM1,DMPK,DOCK2,DPYSL2,DNAJB6,ABCC5,E2F5,TSPAN5,EDN3,PHC2,CELSR3,SUGP2,EGR3,EIF4G2,EMX2,EPB41L2,LRRC17,RASGRP2,ERCC2,DENND4A,RRAGB,SH3YL1,PTK2B,TUBB3,RACK1,FKTN,AMOTL2,ATP5PD,UBE2E3,AGAP2,PDLIM5,TRIM16,RASL10A,KHDRBS3,CSPG5,STAU2,FYN,IQGAP2,SEPT9,GNG4,FERMT2,LILRB4,GPD2,LILRA2,GPER1,GRIN2C,CIT,PSIP1,RNFT2,HAS2,PACSIN2,NCKAP1L,ATXN2L,ACOT7,GABARAPL2,IDH3A,IDH3B,INPP5B,ITPKB,JAK2,KCNN3,KHK,KIF2A,STMN1,SMAD1,MAT2A,MEIS2,MIA2,MSR1,PTOV1,NEFM,CNOT4,SETD4,OCRL,OGG1,ABCB1,PKM,GPSM2,PLEC,SMOX,POLR2F,PRKACB,PKIA,MAPK9,MAPK10,PRPSAP2,CNNM2,NDUFS7,QDPR,RBBP8,RDX,RGS3,SBF1,ATXN2,SCP2,SEC14L1,SGK1,MYO18A,FNDC3A,ST6GAL1,CCDC92,ABLIM3,SLC2A5,SLC12A2,SMARCA4,SNRPN,USP33,DOK5,SPTAN1,DDN,LMO3,POGZ,STXBP1,NSFL1C,DNAJC9,PLCB1,SYP,SYPL1,MMS19,TAF6,KIAA0930,CUX2,SYNE1,DOCK9,ITGB3BP,TIAM1,R3HDM1,CABIN1,TP53BP2,RUSC1,TSN,SSBP2,TTC3,ZKSCAN5,TUBB2A,UCHL1,GORASP1,VAV1,CLDND1,XPO1,ZBTB14,ZNF23,ATP6V0E2,EVI5,MPPE1,PHTF2" Coexpression M1369 Predicted targets of SOX9 [GeneID=6662] that are down-regulated during early prostate development. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.38E-04 1.00E+00 1.28E-02 1.27E-01 13 45 "SLIT2,ZNF521,CRMP1,PUM1,RASSF2,OLFM1,IGF1,STMN1,MEIS1,NFIX,PCDH18,TCF4,TIAM1" Coexpression M9150 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.42E-04 1.00E+00 1.29E-02 1.28E-01 55 323 "ALK,APC,GAS7,BLM,JAZF1,CARS,RUNX1T1,USP6,CHN1,CLTC,PDE4DIP,EGFR,GPHN,ERBB2,ERCC2,ETV1,FGFR1,FGFR3,FOXO3,SPECC1,SEPT9,MALT1,CNTRL,PSIP1,HLF,JAK2,KIT,KTN1,LIFR,LMO2,AFF1,AFDN,MN1,MYCN,NACA,NF1,NTRK3,RAP1GDS1,RET,FBXW7,ZNF331,TET1,FNBP1,ERC1,ARHGAP26,SS18,TAL1,TCEA1,TCF12,NSD1,KAT6B,TSC1,TSC2,WRN,FIP1L1" Coexpression M10431 Genes down-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.56E-04 1.00E+00 1.31E-02 1.29E-01 38 203 "ACADM,SRPX,APLP1,NCOA1,C5,CACNA2D1,CLDN10,RGN,CDO1,DMD,DMPK,DPP6,DENND4A,GATM,GRB10,ICA1,IL6ST,LSS,MAT2A,SHC3,MEST,MXI1,NRCAM,NTRK2,NUCB2,PAX6,MAPK9,PTH1R,PTPRN,PTPRN2,RDX,RNASE1,SGK1,SNRPN,ITPRID2,KANK1,ZNF32,KCNAB1" Coexpression M12176 Genes down-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.66E-04 1.00E+00 1.32E-02 1.31E-01 39 210 "ABHD6,C1QTNF3,PLA2G4C,ASPA,SLC4A4,ST3GAL5,LDB2,RAB33A,FAM189A2,MYRIP,KIAA0040,HDAC9,DAPK1,MFAP3L,NR1D2,RCAN1,FRY,AMOTL2,GATM,GHR,GLUL,SYNPO,IGF1,IL6ST,KHK,LAMA2,PACRG,ZNF862,NBL1,SNRK,PTPRB,FAT4,RASGRF1,LIMS2,ZSWIM8,ZEB1,TNS2,TK2,TST" Coexpression 18062813-GeneList Rat Breast_Moral07_163genes_BBP_treated GeneSigDB 9.67E-04 1.00E+00 1.32E-02 1.31E-01 23 104 "ADD1,RASL11B,AZGP1,ARHGEF7,GPC2,CAMK2B,ARHGEF1,DLGAP2,CELSR3,GABBR1,GABRG2,GAD1,GRIK4,GRIN2D,HSF2,OXTR,RNASEL,SCN2B,SLC12A4,SYT1,MCF2L,TCF4,TSN" Coexpression 15297395-SuppTable1 Human Lymphoma_Sriuranpong04_670genes_Epithelium(N)Metaplastic/DisplasticLesions(R)Carcinoma(T) GeneSigDB 9.69E-04 1.00E+00 1.32E-02 1.31E-01 73 456 "AXIN2,BRAP,NME5,KIAA1324,OSBPL6,ALCAM,AMPD2,OGT,EP400,UPRT,DDO,CDK10,ARHGDIA,PDE8B,RIPK1,RAB29,CAPN3,CAST,CLDN10,NPIPA1,MS4A7,RAB28,CLTC,FBXO7,ABCG2,PYGO1,C2CD2L,ZC3H11A,DMTF1,ARRDC4,TOM1,EEF1D,EIF4G1,EIF4G2,ENO2,ETV1,EZH1,FCGRT,TMEM164,FHL1,GALC,GHR,BRD8,KIAA1958,HSPA1L,MSL1,STMN1,LMO2,ADAM11,POC1B,MITF,NUCB2,OXTR,PKD1,PKM,KLK6,RIC8B,YY1AP1,SLC22A4,TET1,SMARCD3,RBM26,SYN1,COBL,TRIM2,DOCK9,TMPO,TP53BP1,NEIL2,VSNL1,ZBTB14,DNALI1,HNRNPA3" Coexpression 16473350-Table2 Human Brain_Jrgensen05_19genes GeneSigDB 9.74E-04 1.00E+00 1.32E-02 1.31E-01 6 12 "TMCC3,B4GALT6,CNTN1,LRRC3B,TOX2,SLC10A4" Coexpression M1747 Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.74E-04 1.00E+00 1.32E-02 1.31E-01 6 12 "AMPH,CADPS,MAP4K4,APH1A,EPB41,ZBED3" Coexpression M262 Genes discriminating responses to sodium arsenite [PubChem=26435] from other stresses. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.74E-04 1.00E+00 1.32E-02 1.31E-01 40 217 "SPARCL1,OGT,APBA2,ARNTL,ATP6V0A1,ST3GAL5,CARS,CCPG1,TPP1,CTH,DNAJB6,E2F6,ASB3,RPS6KC1,TAOK3,DLC1,FOXO3,ATP2C1,AP4B1,CIT,GUCY1A1,HSPA1L,IL6ST,KCNF1,KIFC3,NFE2L2,PLTP,MAPK7,PTPRB,REV3L,HSPA4L,CPEB4,TBL1X,TSC1,UBE2H,ZNF24,ZNF184,ZSCAN26,ZFAND5,FXR1" Coexpression 16498405-TableS3 Mouse Kidney_Takemoto06_388genes_cat1 GeneSigDB 9.88E-04 1.00E+00 1.34E-02 1.33E-01 52 302 "METAP1D,C1QTNF1,ADGRF5,PRX,THSD7A,LDB2,LRRFIP1,SNCAIP,DOCK4,EDNRB,OPTN,CALCRL,FLT1,FYN,PCDH17,STON1,PARD3B,SYNPO,ITPKB,LMO2,MAPT,MEF2C,MEIS2,MEST,MMP17,NBL1,NCF2,NELL2,SERPINI1,SCHIP1,PTN,PTPRO,RIPOR1,ZDHHC14,ROBO2,MAPK12,GALNT10,SGK1,SMARCA4,UNC5B,DDN,CLASP2,RHBDL3,TMEM150C,PDLIM2,ZEB1,TNS2,WBP2,NR2C2,UBC,CRB2,RTN4" Coexpression 19269367-TableS1 Mouse StemCell_vanderFlier09_134genes GeneSigDB 1.00E-03 1.00E+00 1.35E-02 1.34E-01 22 98 "ADORA1,SORCS2,SEMA7A,LGR5,CRLF1,PLEKHB1,LRIG1,DGKG,NRN1,NKD1,PIK3R1,PTPRD,PTPRO,HUNK,SCN2B,TNFRSF19,SLC12A2,SLC14A1,SMARCD3,TACC1,PDLIM2,RGMB" Coexpression M13256 Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.02E-03 1.00E+00 1.38E-02 1.37E-01 36 190 "BEND6,SRPX,CEP126,NRP2,CA12,PRC1,LRRFIP1,CLGN,ZNF521,VCAN,HEPH,NR1D2,ECM2,EBF1,EGFR,PCOLCE2,ETV1,SCARA3,GALNT15,GPER1,HAS2,HNMT,KITLG,MMP16,SFR1,CLDN11,PDE4B,GNG2,GPSM2,PTN,RPS6KA2,TNFRSF19,FHOD3,SLC2A5,PDZRN3,PLCB1" Coexpression M1350 Genes up-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-03 1.00E+00 1.38E-02 1.37E-01 77 487 "KDM5D,ARHGAP20,TRMT9B,PHYHD1,RASL11B,ATP1A1,N4BP2L1,ADGRB1,SEC11C,IL33,CALB1,CALM1,USP2,FAM149A,COL4A5,COL9A3,TBPL1,SIPA1L1,USP6NL,HDAC9,AIF1L,EDN1,TENM1,PCOLCE2,CALCRL,NRN1,SH3YL1,ACSL4,FGF12,FGFR3,CSPG5,FUT9,MTHFD2,ACSS1,IGSF5,ADAM28,GLUL,KCNMB4,GSN,GABARAPL2,KCND2,KCNJ16,KIT,LAMP2,GPR155,MBP,AFF1,N6AMT1,PCDH9,ZFYVE21,PLCD1,SMOX,DRAM2,GDPD1,MASP1,GDPD2,ELOVL2,PTN,PTPN13,PID1,ZDHHC14,SGK1,HKDC1,SLC12A2,ARC,PDLIM2,TRIM2,FAM189A1,C9orf85,CA14,TST,RPRM,FAM155A,VLDLR,LYPD6,SEMA3B,WNK2" Coexpression M945 Genes up-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI (TNFRSF13B) [GeneID=23495]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-03 1.00E+00 1.38E-02 1.37E-01 21 92 "PI16,APOC2,PPFIA3,PRX,AZGP1,DDR1,CCDC151,PICK1,AKAP7,COL11A2,HS3ST2,MAMLD1,GABBR1,GGTA1P,KCNH2,MBP,MITF,GIT1,NTRK3,SLC6A8,SOX15" Coexpression M361 Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 3h. MSigDB C7: Immunologic Signatures (v6.0) 1.03E-03 1.00E+00 1.38E-02 1.37E-01 32 163 "CARNS1,C2CD2,CRY2,RIPOR2,HIPK3,PHF20L1,GMPR2,SYT17,TNRC6A,NRBP2,PDE4B,PDE4D,PKD1,DRAM2,ZIK1,ZDHHC4,EXD2,FBXW7,AP1AR,FAM102A,SPP1,ARHGAP26,TROVE2,STAU1,ANKRD28,USP22,SIK3,CLDND1,RICTOR,SPHK2,RNF103,RTN4" Coexpression M8006 Genes up-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 1.04E-03 1.00E+00 1.40E-02 1.38E-01 37 197 "ASIC1,ALDH7A1,NOG,FOXN3,CHN2,LY86,HDAC9,ARHGAP32,DAPK1,DPYSL2,C3orf18,CEP85L,HVCN1,ZNF234,SEPT9,GCNT2,SPIN1,GLUL,GUCY1B1,MSL1,ZNF667-AS1,NFE2L2,PCDH9,ZDHHC14,RXRA,SEC14L1,SGK1,BTBD3,LIMS2,USP33,SYPL1,DNMBP,TCF4,TRIO,ZNF711,INTS3,SENP7" Coexpression M8159 Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.04E-03 1.00E+00 1.40E-02 1.38E-01 37 197 "NME5,ALK,PLA2G4C,ATP2A2,KSR1,THSD7A,RHBDL1,KRIT1,DCLK1,AKAP12,ZNF804A,DYNC1I1,HEYL,IRAK4,VPS13B,PTK2B,ARFIP1,PRUNE2,MAP2,NCAM2,SMOX,SEPT4,PILRA,PPP2R2B,PTPRD,RGS12,PKNOX2,SOX11,SYP,FBXW11,KIAA0930,TRIM2,PPIL6,ZNF154,PHTF2,FXR1,JPH3" Coexpression M14371 Down-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.04E-03 1.00E+00 1.40E-02 1.39E-01 96 632 "CLK4,ABHD6,ESYT2,SEMA6A,BACH1,NRP2,KSR1,ARHGEF7,IL33,CACNA2D1,CALB1,CAST,CLDN10,FOXN3,CNOT8,QKI,COL4A5,LETMD1,CPS1,SNCAIP,LRIG1,PNPLA8,PPP6R2,SGSM2,SEC16A,DMD,SEZ6L2,FAM13A,ENO2,MRPL10,NRN1,SH3YL1,CHST15,FGFR3,CAMKK2,ZNF44,GALC,SYT17,GLYR1,GLUL,ZNF638,RAB40B,ZNF496,HNMT,HP,RBPJ,KCNK3,LAMP2,LMO2,NCOA7,ZNF680,MXI1,NELL2,NPTX1,ETFRF1,PCSK1,PDE4B,PDE4D,FA2H,DRAM2,PPARA,GRAMD1C,PTPRO,TUG1,ZNF493,ZDHHC4,SLC25A36,ROBO1,RPL15,RXRA,SATB1,COPZ1,SHMT2,FNDC3A,SEC31A,WDR37,BTBD3,SLC6A8,COA1,RCOR3,KDM4B,FNBP1,KDM3A,SPP1,UNC5B,IQSEC2,SYNE2,TBL1X,PCDHB10,OBSL1,HEY1,TNS1,TTC3,VLDLR,ZNF24,PCBP1-AS1" Coexpression 16151515-TableS4 Mouse StemCell_Forsberg05_606genes GeneSigDB 1.05E-03 1.00E+00 1.41E-02 1.39E-01 53 310 "NDRG3,NDRG2,KLHL13,LRCH2,ALDH7A1,DST,SGCE,CAMK2B,LDB2,FOXN3,ABCG2,FAM171B,TCAF1,ARRDC4,SUGP2,TNK2,TUBB3,FCGRT,FHL1,SESN1,GHR,GLUL,GPD2,GRB10,GRIN2C,GUCY1A1,ICA1,AFDN,MMP16,NRBP2,MYCN,CDK18,DEF8,PTN,PTPN13,MEG3,SEC14L1,SLC8A1,SLC12A2,SNRPN,PDZD2,TROVE2,SEPT8,DMXL2,DOCK9,OBSL1,TEK,CBX5,BEX4,CCDC136,NDRG4,FXR1,IFT88" Coexpression 20436685-ST4-2 Human Breast_Pothuri10_526genes GeneSigDB 1.06E-03 1.00E+00 1.41E-02 1.40E-01 78 495 "ADD1,MTUS1,ANK2,GAS7,NUMB,RGS11,CFLAR,CALB1,KALRN,CAMK2B,CH25H,RUNX1T1,SEPT7,LRRFIP1,CDO1,LHX2,NRXN3,ABCG2,CNN3,PICK1,CLOCK,CNTNAP2,DAPK1,CHRDL1,EXOG,EIF1,ETV1,FGFR1,FYN,GATM,GLUL,DCLK2,LILRB4,HLF,IFI16,IL6ST,FAM69A,KHK,KTN1,MAPT,MBNL1,MEIS2,MT1M,NF1,PDE3A,PSAT1,LRRN3,PPP3CC,MAPK7,GDPD2,TMEM104,RASGRF1,RET,RORB,GALNT10,CHD9,SEC31A,INTS9,SNCA,ATP10B,CLSTN2,STX1A,ARC,MGRN1,DOCK9,OBSL1,NSD1,TNS1,TPM1,SYNPO2,TRIO,TSC2,UBC,CLDND1,TRIM9,REEP1,ZFAND5,SEMA3B" Coexpression M6751 Genes up-regulated in splenic dendritic cells versus 33D1+ B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.42E-02 1.41E-01 30 150 "SYT13,CDC42BPA,ATP6V0A1,RIPK1,CD38,FOXN3,NECTIN3,EDNRB,PCOLCE2,CALCRL,ATP13A4,FLYWCH1,FOLR2,SARAF,GGT5,GSTT2,ADAMTS6,VSIG4,P2RX7,POLG,NDUFS7,MTMR10,RNASEL,LGI2,ST6GALNAC6,PPM1E,PEG10,ATP10B,RTN4,FRMD6" Coexpression 12509443-Table2 Human ProteinKinases_Frevel03_425genes GeneSigDB 1.07E-03 1.00E+00 1.42E-02 1.41E-01 65 398 "ABR,ACADM,MADD,EIF4G3,ATP2A2,ARHGEF7,MTMR2,PRC1,CBLN1,USP6,NPIPA1,SRSF11,RNF14,VCAN,KIAA0040,PPP6R2,DBT,YTHDC1,RUSC2,GOLT1B,EDN3,EDNRB,SRRM1,VPS26C,SIRPB1,PTK2B,PDLIM5,GALC,MTHFD2,GRB10,BTN2A1,IDH3A,IGF1,MATN3,MEF2C,AFF1,MPP2,NCAM2,NFE2L2,NOVA1,PDE4B,PLCL1,STRN3,POU6F1,PPP3CA,RBBP8,FNDC3A,WDR37,SNAP25,ZBTB43,ITPRID2,STAU1,NEK4,ARHGEF9,TACC1,ATMIN,TCF12,PCDHA6,SIRT1,AKTIP,UBE2H,EVI5,SEMA3B,NAV3,IFT88" Coexpression M7068 Genes whose expression in optimally debulked ovarian tumors is associated with survival prognosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-03 1.00E+00 1.42E-02 1.41E-01 44 246 "RALGAPA1,NDRG3,APBB2,MARK4,NCOA1,WASF1,NFS1,CLDN10,FOXN3,CRY2,ARHGAP24,SPATA2,SACS,OPTN,AASS,FLT1,ATP6V1H,NSG1,FYN,GAA,IQGAP2,TMEM8B,BTN2A1,GSN,IFI16,OPA1,PCSK5,PLXNB1,MSANTD2,RGS3,EXD2,STK32B,SLC14A1,ATF7IP,DOP1A,SOX11,DOK5,ZHX3,SP4,CDK19,JMJD6,SYT1,DNMBP,NSD1" Coexpression M2388 "Transcripts in hematopoietic stem cells (HSC) which are trans-regulated (i.e., modulated by a QTL (quantitative trait locus) not in a close proximity to the gene)." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-03 1.00E+00 1.42E-02 1.41E-01 128 882 "ABCF1,CLK4,ADCY6,AXIN2,AK2,ALK,NUMB,ATP1A1,SLC4A4,MPDZ,RGS11,HCN2,BID,PROM1,CACNA1G,DDR1,SLC25A14,CDO1,NOG,CNOT8,TPP1,CRY2,RNF14,HINFP,CSNK1E,PDE4DIP,GPSM1,MATR3,B3GAT3,SEC16A,NR1D2,DMTF1,DUSP9,GOLT1B,EDN1,EDN3,ANKRD46,RASA4,ASB3,SRRM1,PIPOX,CD320,FCGR1A,FDFT1,PRMT5,FGFR1,AMOTL2,HPCAL4,SYT3,TPK1,ATP6V1H,USP19,ZNF276,GLUL,GRIK5,GRIN2C,GRIN2D,GSTT2,IGFBPL1,AGFG1,IRF8,RBPJ,IL6ST,KCND2,KIFC3,SMAD1,MBP,MMP17,MSR1,MYO5A,MYO6,NEFM,NEK1,NFIX,SETD4,PCSK5,PIK3R1,SNX10,MAPK7,WBP1L,ELOVL2,ZIK1,EML5,PTPRN,RAD17,RNH1,MAPK12,SEMA6D,SCN8A,FOXRED1,SH3BP2,FHOD3,ST6GAL1,SLC12A4,ZKSCAN3,SOX15,SP4,STAU1,PHLDB1,KLHL7,PLCB1,TCF4,KIAA0930,CUX2,TNS2,FRYL,TEK,DICER1,AKTIP,MTMR14,NACC2,CBX5,WBP2,NR2C2,UBTF,VAV1,VLDLR,TBC1D15,WIPF1,WNT7A,NPDC1,REEP1,SMARCAD1,RNF103,TUBA1A,FZD3,ST7,FXR1" Coexpression 17510434-Table2 Human Breast_Lin07_38genes GeneSigDB 1.07E-03 1.00E+00 1.42E-02 1.41E-01 10 30 "ADORA1,PPP6R2,GRIK4,SFXN5,NCF2,GPR173,PPP2R2C,STK32B,SBF1,IFT122" Coexpression 16760442-SuppTable5-1 Human Lymphoma_Hummel06_50genes GeneSigDB 1.07E-03 1.00E+00 1.42E-02 1.41E-01 10 30 "BMP7,WASF1,PTBP2,BACH2,FHOD3,SMARCA4,SOX11,SSBP2,UCHL1,PRDM10" Coexpression 15358818-table1 Human Stomach_Yuan04_32genes GeneSigDB 1.07E-03 1.00E+00 1.42E-02 1.41E-01 10 30 "ARHGEF7,DCTN1,TNK2,TUBB3,DCTN2,GNAL,HSPA1L,SMARCC2,SPTAN1,SYNE2" Coexpression 18435859-ShorterGeneList Mouse Breast_Piechocki08_558genes GeneSigDB 1.08E-03 1.00E+00 1.43E-02 1.42E-01 62 376 "ACTN1,NDRG2,ABCD2,GAS7,TMEFF1,NRP2,BMPR1B,SGCE,CD38,CDH2,ABCG2,CNTFR,ABCG1,CSF1,VCAN,SPOCK2,SACS,ABCC5,EGFR,MBNL2,CERCAM,HSPA12B,FGF1,CSPG5,CHL1,IGSF5,TUBA8,GHR,GSN,IRAK3,HAS2,IL6ST,ITGA7,LAMA2,MAPT,MATN2,MATN3,MID1,MMP16,MYO9A,SERPINI1,PCDHB17P,PPP2R2B,MASP1,KLK6,TNFRSF19,ABLIM3,MAST1,PCDHGA11,PCDHB7,PCDHB3,TNS2,CHST8,TNS1,TPM2,TRO,FLRT2,WNT7A,TUBA1A,ADAMTS9,FZD3,NETO1" Coexpression M8894 Genes down-regulated in multipotent progenitors versus pro-B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.09E-03 1.00E+00 1.44E-02 1.43E-01 34 177 "PPP4R4,ADAM15,SYNJ2,ARHGEF7,CAST,TPP1,AKAP7,CREM,CSF1,CD99L2,ARRDC4,SNX29,EGR3,KATNAL1,GGTA1P,ZHX1,HSF2,KIT,LIG4,MXI1,PDE1B,PLCL1,CNNM2,MAPK12,ANKRD6,ABLIM3,ZFP1,KIF13A,TEX2,ERC1,SYPL1,SLC37A2,IQCE,PHTF2" Coexpression M1610 All significantly up-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.09E-03 1.00E+00 1.44E-02 1.43E-01 69 428 "DGCR6,KIAA1324,SRPX,CPNE5,IGDCC4,BCL7A,NRP2,BLM,IL33,CA4,MTMR7,DCLK1,SLIT2,FAM189A2,NSL1,SIPA1L1,VCAN,GREB1,BOC,SNAP91,EDNRA,RGS17,EYA1,RACK1,FCGRT,SPSB4,FLNC,FLYWCH1,MPP6,IGSF5,GSTT2,IGF1,NKD1,LAMA2,STMN1,MATN2,MEIS1,MMP16,MSI1,MYCN,NFIX,PALM,PCDH8,PCDH9,PLTP,PSAT1,PRKAR1B,RELN,PTN,TMEM231,LGI2,EMID1,MEG3,HUNK,SLC4A3,TET1,CXXC4,SOX11,CLSTN2,SYNE2,DNAJC9,ZFPM2,CBX5,HSPBP1,RBFOX3,KCNT2,CELF4,SLC38A1,PCBP4" Coexpression M250 Genes down-regulated in macrophages by P.gingivalis FimA pathogen. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.11E-03 1.00E+00 1.47E-02 1.46E-01 49 282 "NDRG2,CCDC85A,PPFIA4,PRMT9,ZNF555,USP2,SLC16A4,RCBTB2,CNOT8,CPNE6,NRXN3,CPS1,DBT,SGSM2,ECM2,TMEM107,ZNF605,AP4B1,RAB40B,MCHR1,MUM1,KLHL23,SMAD1,AQP11,MBP,SHC3,THYN1,PRIMPOL,CYBC1,PTPRO,MARCH1,RPE,ZC3H14,SCN7A,CHD9,CNKSR2,ARHGEF40,TMCC1,GLT8D1,PCDHGC5,ENHO,HIRA,WIPF1,ZBTB14,ZNF540,REEP1,JMJD1C,NHSL1,DPF3" Coexpression M1110 Up-regulated genes from the set A (Fig. 5a): specific to cells expressing MLL-AF4 [GeneID=4297;4299] fusion protein alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.13E-03 1.00E+00 1.49E-02 1.48E-01 36 191 "PCDH19,APC,CNRIP1,GDA,ARHGAP32,TCAF1,MATR3,GIT2,GSDME,DTNA,EBF1,ST3GAL6,FLT1,BRD8,TNRC6A,TDRKH,KAT7,MARK1,MYO5A,PRTG,PFKFB2,SH3KBP1,SETD5,RPL15,ADAL,WDR37,BTBD7,ANKRD28,TRIM2,GPRIN3,NR2C2,WIPF1,TRIM9,NAV3,JMJD1C,ZDHHC20" Coexpression M2781 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 29 144 "NDRG2,GAS7,COL9A3,CREM,CLIP3,ETV1,CHL1,TRAF3IP2,GPR162,PPARGC1A,STON1,PADI2,KCNJ16,PCDH8,PDE4B,PRPH,WDR25,PID1,C1orf54,PNMA8A,KANSL3,DOK5,NMNAT2,ZNF423,LMO3,TRIM2,CDH22,TRPS1,SSBP2" Coexpression M1349 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 15 57 "AMPH,CRMP1,LYPD1,TUBB3,OLFM1,STMN1,TAGLN3,NEFM,NNAT,NTRK2,PCDH8,PRPH,RASA3,LIMS2,MTCH1" Coexpression M5492 Genes down-regulated in comparison of macrophages versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "APAF1,STX16,AZGP1,BACH1,SLC25A14,ARHGEF1,LRRFIP1,NDST3,ABCC5,EEF1D,PLXNC1,EYA1,FOXO3,ZNF44,GRIA2,BTN2A1,KAT7,LSAMP,MARK3,SAMD9,PTPRG,SCN2B,SEC14L1,GALNT10,PPM1E,SLC6A11,MYO16,UHRF1BP1L,UNC5B,SYNE2,ANKRD12,PDLIM2,AGTPBP1,PUM2,DICER1,CABIN1,NLRP3" Coexpression M8226 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype untreated versus RORC [GeneID=6097] knockout treated by digoxin [PubChem=2724385]. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "ARNTL,ARHGEF7,PRC1,CD38,ARHGAP33,WHRN,EPB41L2,MTSS1L,KATNAL1,TUBB3,FECH,FGFR3,FRMD3,MIER3,LSS,PURG,SNRK,GAL3ST4,ERI2,RIC8B,DCUN1D2,STK32B,SMPD3,HKDC1,SLC12A4,GKAP1,TMCC1,ZC4H2,ELOVL4,SYNE2,DNMBP,TCF12,C18orf54,KAT6B,USP1,ZNF709,TTC7A" Coexpression M8003 Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "RNF157,KCNAB2,ZFYVE28,ASGR1,RGS9,CD86,ANKRD35,TRIM69,FAM169A,SPATA2,RCAN2,F5,PRKAG2,AGAP3,IQCG,IQGAP2,RNPS1,GAREM2,MYO5A,BEX5,TBC1D25,KCTD15,JAKMIP1,PTPN13,RADX,GTDC1,RNH1,SEMA6D,KIF21A,TRERF1,SUPT5H,DOCK9,NACC2,FAM124A,ANKS1B,EVI5,FZD3" Coexpression M8157 Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "NME5,BIN1,APOC1,APOC2,ATP2A2,MYOM1,BAIAP3,THSD7A,KRIT1,SLIT2,FHL5,CLIP3,SPATA2,PLEKHA1,VPS13B,STMN2,SLC2A6,KTN1,NCAM2,NELL2,OPA1,PALM,MARCH1,RAD17,CARF,CCDC92,PREX2,KDM4B,SOX11,TSPYL2,PRRC2C,MMS19,FAM208A,FBXW11,METTL3,PHTF2,JPH3" Coexpression M4218 Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h versus the untreated cells at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "ABHD6,OLMALINC,ARRB1,EIF4G3,HAP1,NOG,IPCEF1,PHACTR3,DGKB,FAM107B,AASDH,ATP2C1,MALT1,CRCP,GNAL,GPD2,TDRKH,MAP4K5,TOX2,IL6R,IL12A,MBP,LRP1B,SAMD5,MXI1,NINJ2,PDE4D,PFKFB3,CCDC82,SGK1,STAC2,GPRIN3,R3HDM1,NPL,CLIP2,TTC7A,JPH3" Coexpression M8272 Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout: control versus stimulated by anti-IgM for 8h. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.49E-02 1.48E-01 37 198 "CARNS1,LTBP4,ALK,ZFYVE28,ARNTL,ZBTB10,ARHGEF7,CFAP410,CACNA2D2,ENTPD4,CRY2,ELMSAN1,NR1D2,FOXO3,ZNF276,RAB30,TNRC6A,BACH2,AGFG1,IBA57,ITPKB,NFE2L2,SLC11A2,PDE4B,ABCB1,PIK3R1,NCR3LG1,PTPRE,FAM102A,EPC1,TSPYL2,STX1A,DNMBP,SIRT1,TP53BP2,SGK3,KAT6A" Coexpression M2226 Genes up-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-03 1.00E+00 1.50E-02 1.49E-01 79 504 "NDRG2,RNF157,OSBPL1A,ALCAM,MYH7B,EPB41L5,SEMA4G,NRP2,C5,CCNT1,CDH2,CLCN3,ABCG2,HECTD1,MAGED1,C2CD2,SV2B,EXOG,DMPK,DUSP9,DNM1L,EDNRB,KMT5B,ING4,PAN3,MRVI1,ABCA8,SH3YL1,ACSL4,DLC1,FECH,GTF2IRD2,FOXO3,FLT1,OGA,MTHFD2,GHR,FERMT2,GRB10,GUCY1A1,AGFG1,C2orf72,KIF2A,MBNL1,MSR1,OLA1,SEMA5B,PMP22,MAGEL2,SEPT4,DRAM2,MASP1,VPS13C,PTPRB,PTPRD,NWD1,MEG3,SEMA6D,WDR37,SLC6A8,CPEB4,SNCA,CLASP2,MESP1,ST5,APOM,NSFL1C,PUM2,FRYL,SLC44A1,TMEM9,TRIO,TUBB1,FTSJ1,ZFAND5,EMSY,CIAPIN1,MRPL47,SNX14" Coexpression M2580 Genes consistently down-regulated in mature mammary luminal cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-03 1.00E+00 1.50E-02 1.49E-01 22 99 "AXIN2,SPARCL1,LTBP4,FOXN3,B4GALT6,MAP4K4,ZNF521,TIAM2,DPYSL2,FAM13A,EGFR,EPB41L2,RASL12,C2orf88,ITPKB,MEIS2,NTRK2,IRX1,LAMA1,RASA3,PDZRN3,STAC2" Coexpression M1755 Genes up-regulated after Cre-lox knockout of APC [GeneID=324] in the small intestine. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.16E-03 1.00E+00 1.51E-02 1.50E-01 39 212 "RALGAPA1,ADCY8,AXIN2,TRMT9B,NT5C3B,NFS1,DIS3L,STOML1,NECTIN3,ANKRD44,GPSM1,DCAF4,DGKB,AASDH,EDN1,C2orf88,SRCAP,BRD8,MSI1,CLDN11,PSAT1,MAPK4,RGS12,RNASE1,MEG3,HUNK,TNFRSF19,GALNT10,SHMT2,DHX30,ZFP1,CABCOCO1,CLASP2,TTBK2,CAMTA1,TIAM1,HIRA,ZNF184,MRPL47" Coexpression M8186 Genes up-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 1.18E-03 1.00E+00 1.52E-02 1.51E-01 33 171 "ABR,AS3MT,SEMA7A,ATP6V1G2,NRP2,BID,CD86,CD38,CDC42BPB,CYBB,ARHGAP24,PLXNC1,PLEKHA1,EMX2,TLR7,DLL3,LILRB4,RNFT2,MATK,PDE4D,PKD1,SH3KBP1,DRAM2,RASGEF1B,PTK2,ZDHHC14,RPS20,MYCBP2,PDLIM2,TCF4,RUNDC3B,TRPM2,PLD4" Coexpression 19893615-Table3 Human Thyroid_Fontaine09_220genes GeneSigDB 1.18E-03 1.00E+00 1.52E-02 1.51E-01 33 171 "ALCAM,ANK2,VAT1L,ASGR1,ATP6V1G2,CALM1,CBFA2T2,CD38,CLGN,NUMBL,CERCAM,EMX2,ABCA8,GRB10,IDH3B,ZNF862,NBL1,PAX6,ABCB1,CEP97,KLHDC8A,RPS6KA2,SLC6A8,TTC17,ZNF415,SST,KIAA0930,FAM124A,CABIN1,TPM2,DNALI1,ADAMTS9,AAAS" Coexpression 15906272-Table5 Mouse StemCell_Greijer05_57genes_DownRegulatedbyHypoxia GeneSigDB 1.18E-03 1.00E+00 1.52E-02 1.51E-01 13 46 "ALCAM,SEPT7,COL4A5,YTHDC1,CASP8AP2,SMC2,PSIP1,KTN1,PAXBP1,HNRNPM,REV3L,TCEA1,TMPO" Coexpression 15860665-Table1 Mouse Leukemia_Muntean05_74genes GeneSigDB 1.18E-03 1.00E+00 1.52E-02 1.51E-01 13 46 "TMCC2,RASGRP2,TUBB3,LIFR,MEST,NPY,SERPINI1,GRAMD1C,RELN,SNCA,NACC2,P2RY12,PRRT4" Coexpression 15906272-Table2 Mouse StemCell_Greijer05_57genes_DownRegulatedunderHypoxia GeneSigDB 1.18E-03 1.00E+00 1.52E-02 1.51E-01 13 46 "ALCAM,SEPT7,COL4A5,YTHDC1,CASP8AP2,SMC2,PSIP1,KTN1,PAXBP1,HNRNPM,REV3L,TCEA1,TMPO" Coexpression M2491 List of genomically imprinted genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.20E-03 1.00E+00 1.55E-02 1.54E-01 16 63 "APOC2,SFMBT2,SGCE,GATM,GRB10,SCIN,MEST,NNAT,CNTN3,MAGEL2,RASGRF1,MEG3,SNRPN,PEG10,UBE3A,MKRN3" Coexpression M19439 Genes up-regulated in breast cancer samples positive for ESR1 [GeneID=2099] compared to the ESR1 negative tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.21E-03 1.00E+00 1.56E-02 1.55E-01 24 112 "KIAA1324,ALCAM,AZGP1,BMPR1B,CA12,CLGN,SLC4A8,GREB1,ERBB4,EVL,SYT17,TOX3,MAPT,MYO6,ELOVL2,RET,STK32B,SYBU,IFT122,CLSTN2,SYT1,MAP3K12,DNALI1,SEMA3B" Coexpression 15459216-TableA2f Human Leukemia_Haslinger04_126genes GeneSigDB 1.21E-03 1.00E+00 1.56E-02 1.55E-01 24 112 "OGT,EP400,BCL7A,FUBP1,HIP1R,MAP4K4,CS,GIT2,DNM1L,CELSR3,RASGRP2,TAOK3,RNFT2,IRAK3,NCKAP1L,MAN2A2,RASGRF1,ATXN2,SHMT2,R3HDM2,SLC2A5,ERC1,TRIO,ST7" Coexpression M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.22E-03 1.00E+00 1.58E-02 1.57E-01 35 185 "MARK4,DDR1,THSD7A,CH25H,RAB33A,HOMER3,CREM,CRHBP,VCAN,RIPOR2,ZFYVE16,ARMCX2,E2F5,OPTN,CALCRL,PDLIM5,HPGDS,LILRA2,GSN,GUCY1A1,HLF,IFI16,MXI1,NPTX1,NRCAM,NTRK3,PDE4B,MEG3,SAMSN1,FBXW11,SLC35G2,UCHL1,TUBA1A,FXR1,SENP7" Coexpression M9446 Genes up-regulated in splenocytes: control versus infected with Sendai virus. MSigDB C7: Immunologic Signatures (v6.0) 1.23E-03 1.00E+00 1.59E-02 1.58E-01 31 158 "OGT,GPR146,LARGE1,B4GALT6,CLCN3,CNTN1,ABI3BP,NRG2,IPCEF1,RIPOR2,PRAM1,PSD2,GCNT2,NCOA7,PDE4B,MAPK10,RGS12,RNASEL,ATP8B4,LRRK2,KCNIP3,SAFB,RASA3,CCDC88A,ATF7IP,UHRF1BP1L,ZC3H13,CLDND1,GDPD5,HPS4,DOCK8" Coexpression M13671 Up-regulated genes distinguishing between M1 (pro-inflammatory) and M2 (anti-inflammatory) macrophage subtypes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.24E-03 1.00E+00 1.59E-02 1.58E-01 19 81 "FAM135A,FGD2,LCORL,DST,RCBTB2,CNRIP1,GDA,ENO2,ACSS1,GATM,PIK3AP1,LYPLAL1,MSR1,P2RY13,NRCAM,RFX3,FAM124A,TTC3,ATP6V0E2" Coexpression M5397 Genes up-regulated in comparison of eosinophils versus mast cells. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "TAOK1,APBB2,APLP1,CHRD,ATP2B2,LRRFIP1,PITPNM3,GIT2,DBT,DGCR5,EZH1,CAMKK2,USP19,CNTRL,TPPP,GRIA2,GSN,FICD,IL6R,JAK2,MYT1,P2RY13,NNAT,SAMD9,MARCH1,GAL3ST4,LGI2,CCDC82,RXRA,SATB1,SMPD3,SLA,EPN2,IQSEC2,SAMSN1,SYNE2,HRASLS" Coexpression M10033 Genes down-regulated in macrophages: control versus colorectal adenocarcinoma conditioned. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "AS3MT,ARNTL,CAMK2A,CAMK2B,CAMK2G,SPOCK2,PITPNC1,GUCD1,DMD,E2F6,RCAN2,SPEG,ST3GAL6,PDLIM5,ALDH1L1,FERMT2,HSPA1L,ITGA7,IPO5,KTN1,MEF2C,PPM1L,PDZRN4,PPM1B,PPP1R1A,PPP3CA,USP47,SATB1,ZFP2,SMARCD3,TMCC1,TEX2,ADHFE1,SYNPO2,REEP1,PHTF2,KLHDC1" Coexpression M5541 Genes up-regulated in comparison of B cells versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "MARCH3,ZBTB10,CACNA1A,LY86,COL9A3,SMARCAL1,RUBCN,CYBB,E2F6,EPB41L2,TLR7,DLL3,SYT17,GATM,MSL3,RNFT2,IRF8,MEF2C,FA2H,PTPRN2,ZDHHC14,MAPK12,SEC14L1,SHMT2,ST6GAL1,SLC2A5,ZC4H2,ZC3H4,SYPL1,CUX2,USP22,KCNE5,TST,CLIP2,LAT2,ZNF154,SEMA3B" Coexpression M4451 Genes up-regulated in comparison of memory IgM B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "ALK,NCOA1,SLC4A4,KYAT1,CBFA2T2,SYNGR3,LY86,CSF1,ERC2,CCDC144A,ZNF337,SACS,FRY,TNK2,STRADA,SCARA3,PRRC2B,SYNPO,IRF8,RETREG1,PLEC,PKIA,ZCWPW1,RASGRF1,RADX,ZNF532,RPS20,FAM102A,INTS9,KIF13A,SPP1,THRA,ZNF23,ATP6V0E2,MKRN3,KAT6A,ADAMTSL3" Coexpression M8429 Genes up-regulated in CD8 T cells: stem cell memory versus effector memory. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "ABCF1,ACADM,DOC2A,PROM1,CACNB4,CDC25B,CNTN1,COL4A5,DBN1,ELMO1,KIAA0753,TOM1,PLXNC1,F8,CAMKK2,GHR,MSL3,IPO5,KITLG,MSR1,ZNF92,PPARA,LRRN3,PPP3CA,CNKSR2,ST8SIA1,SNAP25,SNCA,ZNF423,MPRIP,ARHGEF9,VPS13A,TBL1X,MGRN1,KAT6B,METTL3,INTS3" Coexpression M8318 Genes up-regulated in NKT cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "PLA2G4C,ARSE,CADPS,RGS9,LHX2,CYBB,MRNIP,SRPK3,KAT8,FGFR1,USP19,LILRA2,CIT,KAT7,IRAK3,PADI2,MMP16,PCBP3,PAX6,PLCD1,PLIN1,POU6F1,MAPK3,RELN,PSD,SCN7A,RASA3,SGK1,ERC1,SYP,CDH22,THRA,TPM1,TPM2,TSN,UCHL1,GDPD5" Coexpression M9739 Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus Ly6c int CXCR5+ [GeneID=643] memory. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "NDRG2,TNRC6C,SPTBN4,HIP1R,CD38,RCHY1,SNCAIP,CSF1R,RASSF2,GIT2,ELMSAN1,GUCD1,RASGRP1,ING4,INPP5K,SESN1,GPR34,IL6R,AQP11,MXI1,P2RY13,RETREG1,PLEC,PURG,POU6F1,MINDY2,PPP3CA,PRPH,PTPRO,C1orf54,CCDC82,TACC1,SLC44A1,LAT2,EVI5,MSRB3,ADAMTS10" Coexpression M6266 Genes up-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] high: AIRE [GeneID=326] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "WDR35,PKP4,ATP1B3,ARHGEF1,ZMYM4,CDC42BPB,LRIG1,TM9SF4,GSDME,MED12,DOCK2,TSPAN5,FAM198B,RPS6KC1,TUBGCP4,KIAA1958,IDH3B,IBA57,MYO6,MYO7A,CNOT4,NPY,ETFRF1,SMIM7,PRKCB,SPDL1,ZIK1,RXRA,ZSWIM8,STAC2,LRRC8A,TRIO,TTC3,FLRT2,AMZ1,TMEM178A,RGS7BP" Coexpression M7382 Genes down-regulated in monocyte derived macrophages: CSF1 [GeneID=1435] versus PF4 [GeneID=5196]. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "C3orf14,CDK13,MYRF,ZNF555,IPCEF1,UBXN2A,HDAC4,TBC1D5,DAPK1,SCRN1,KMT5B,VPS13B,PSMA3-AS1,PCYOX1,IL6R,AFF1,SLC25A48,CCDC112,ATXN7,SEC14L1,WDR47,BTBD7,ATF7IP,SP2,KDM4C,DIP2A,ANKRD12,IQCE,CLASP1,PUM2,DCBLD1,SSBP2,EIF4ENIF1,MPPE1,FZD3,MARCH8,SENP7" Coexpression M3193 Genes down-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "C1QTNF1,KCNAB2,DDR1,ARHGEF1,SRSF11,FAM169A,RASSF2,NR1D2,SUGP2,PLEKHA1,PIPOX,OLFM1,POLR1B,TRMO,SARAF,CHL1,SPIN1,MAT2A,MATK,MBP,MMP17,GIT1,ZNF862,NEK1,PLIN1,RXRA,SATB1,SH3BP2,R3HDM2,SLA,PPP4R3A,BTBD3,ZBTB43,ARHGEF9,TACC1,MTCL1,SYNE1" Coexpression M9930 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-03 1.00E+00 1.60E-02 1.58E-01 37 199 "HECW2,GPRASP2,PDZD4,CACNA2D1,ASIC3,C4orf33,IGDCC3,DMD,EBF1,RASL12,HPCAL4,C2orf88,DLL3,RAB40B,PRDM5,GRM8,KCND2,KCNH2,LAMA2,CAMK2N2,MGAT3,NEXMIF,PCSK5,PDZRN4,PPP1R1A,ELOVL2,MAP6D1,SLC14A1,TET1,PDZRN3,PDZD2,SYN2,PCDHB10,ERCC6L2,HIRA,ZIC1,NETO2" Coexpression 16440291-SuppTable1 Human HeadandNeck_Martens06_209genes GeneSigDB 1.27E-03 1.00E+00 1.61E-02 1.59E-01 38 206 "ADGRF5,SPARCL1,SGCE,IL33,LDB2,AKAP12,CST3,GPRASP1,CHRDL1,EDNRB,FAM13A,RASA4,NRN1,F8,DLC1,FCGRT,IQGAP2,GHR,LYVE1,FERMT2,GUCY1B1,IGF1,IL6ST,MATN2,P2RY13,NELL2,PLTP,PMP22,LRRN3,PTPRE,RNASE1,ZNF423,RGL1,ZFPM2,TNS1,TPM1,FLRT2,PLSCR4" Coexpression 19038878-SuppTable3 Human Leukemia_Lenz08_385genes GeneSigDB 1.27E-03 1.00E+00 1.61E-02 1.59E-01 58 349 "ACTN1,ZNF608,MTUS1,TBC1D14,ADGRF5,SPARCL1,APOC1,IGDCC4,DST,CACNA2D1,CHN1,PCYT1B,ABI3BP,ZNF521,CNRIP1,CSF2RA,VCAN,HEPH,DNM1,ARRDC4,EDIL3,EDNRA,KLHL5,CERCAM,RASL12,KATNAL1,ZNF585B,DLC1,SCARA3,GHR,GNAL,FERMT2,GRB10,PARD3B,GSN,ITPKB,TTYH2,LAMP2,LMO2,KITLG,MITF,PLIN1,PCDH18,PMP22,LRP12,PTK2,PTPRB,ROBO1,RTN1,DZIP1,UNC5B,ST5,OBSL1,ZFPM2,TPM1,SSBP2,MSRB3,FRMD6" Coexpression M18841 The 'MLL signature 1': genes down-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to all AML cases with the intact gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.27E-03 1.00E+00 1.61E-02 1.60E-01 43 241 "BIN1,WASF1,MYRF,BAIAP3,CFAP410,CA4,HIP1R,RUNX1T1,PPT2,CLIP3,SIPA1L1,PPP1R16B,DAPK1,ELMO1,EEF1D,EGR3,DLC1,FDFT1,TRIM16,RASL10A,ATP2C1,ZNF274,GGT5,BRD8,HPGDS,HLF,NBL1,NOVA2,CYTL1,OLA1,ABCB1,RIPOR1,GTDC1,NUDT11,BAALC,STK32B,ASAP3,SLC12A4,SOX11,ZSWIM8,MCF2L,TAL1,TTC3" Coexpression M15835 Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.28E-03 1.00E+00 1.62E-02 1.60E-01 40 220 "ACADM,ALCAM,APBB2,CASK,AZGP1,LRBA,CLGN,UBE2L6,PLEKHB1,CNN3,CNR1,GREB1,MFAP3L,TSPAN5,VPS13B,PDLIM5,NFU1,RBPJ,IL6ST,LAMP2,MMP16,MXI1,NRCAM,PIK3R1,RETREG1,SNRK,ELOVL2,RPS6KA2,AP1AR,DGLUCY,HSPA4L,SYBU,BTBD3,PEG10,PLCB1,SYT1,TACC1,SATB2,FRYL,PHTF2" Coexpression M2214 Genes down-regulated in CD4+ [GeneID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.28E-03 1.00E+00 1.62E-02 1.61E-01 63 386 "AXIN2,EPB41L5,PHYHD1,BBS2,ZNF599,PROM1,CASTOR3,SLIT2,NRXN3,SUMF2,AKAP5,AKAP12,SIPA1L1,TBC1D5,AIF1L,DBT,POM121,DMTF1,SLC12A6,PDCD6IP,EDIL3,EDNRB,FHL1,IP6K2,VTI1B,TPK1,CHL1,GATM,ADGRA3,PCLO,INSYN1,LYPLAL1,MIA2,KITLG,MITF,NBL1,ZNF655,RETREG1,SCHIP1,MINDY2,PRPSAP2,RELN,PTPRD,REV3L,RGS12,CARF,RPS6KA2,LRRK2,SUPT20H,FNDC3A,EPN2,COBL,ASTN2,CAMTA1,WSCD1,SATB2,RUNDC3B,GORASP1,TMEM161B-AS1,LMF1,KCNT2,LOC100506497,PDSS2" Coexpression M6877 Genes up-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il. MSigDB C7: Immunologic Signatures (v6.0) 1.30E-03 1.00E+00 1.62E-02 1.61E-01 33 172 "NCKAP5,MTA3,OSBPL1A,DOCK11,LARGE1,HDAC4,ARMCX4,CALCRL,PAN3,EZH1,PRKAG2,USP19,TOX3,TDRKH,ACOT7,HMGCR,KIT,STXBP5,LIMS1,NCOA7,SNX10,OXR1,ZDHHC14,RNASEL,ATP8B4,HSPA4L,CHD9,SLC12A2,TACC1,CYB561A3,CDK20,PLD4,DOCK8" Coexpression M11028 Genes in the most frequently gained loci in a panel of glioma cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.33E-03 1.00E+00 1.62E-02 1.61E-01 22 100 "SYT13,APOC1,APOC2,MADD,MARK4,DGKI,CRY2,GALNT9,ELMO1,ERCC2,PRKAG2,FOLH1,CLASRP,ZBTB45,PCDH18,RELN,PTPRN2,GALNT10,NLGN1,SMARCD3,SYPL1,VIPR2" Coexpression M6444 Genes up-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [GeneID=5511] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.33E-03 1.00E+00 1.62E-02 1.61E-01 113 769 "ASPHD1,ASIC1,METAP1D,OSBPL1A,WDR35,MARCH4,FAM135A,OGT,NUMB,SLC4A4,JAZF1,RAB28,PPT2,C4orf33,QKI,CNN3,ARMC8,TBPL1,CNRIP1,NECTIN3,SEC31B,CREM,DZIP3,KIAA0408,KCTD8,DNAL1,KLHL3,DMTF1,ANKRD46,SEMA3D,PHF20L1,MRNIP,PCOLCE2,VPS13B,SPEG,KATNAL1,RPS6KC1,ST3GAL6,FGF1,FGF13,SYNCRIP,COQ5,TMEM107,PRELID3A,CELF1,CGREF1,GAD1,ERAP1,ARFIP1,FERMT2,FUT10,GRB10,PLCD4,ADAMTS13,ADAMTS6,HAS2,FRMD5,IFI16,RBPJ,DISP2,GATD1,NCOA7,MATN2,MEST,KITLG,POC1B,NRBP2,MX1,OGG1,ETFRF1,SERPINI1,XRN1,FAM216A,DRAM2,TATDN3,PPP3CC,GDPD1,SAMD9,WBP1L,LAMA1,ENOX1,RGS4,RNASEL,SUGCT,AP1AR,SGK1,SH3BGR,CCDC88A,BTBD7,OGDHL,KDM3A,KDM4C,RBM26,THSD1,SSTR1,ZC4H2,LARP4,NUDT10,TCF4,SATB2,TCF12,DICER1-AS1,RGMB,TSC1,WIPF1,XRCC4,LYPD6,LAMP5,DHX33,ITM2C,NETO2,RNF146,ZNF30" Coexpression 19061838-TableS13 Mouse Viral_Cairo08_620genes GeneSigDB 1.35E-03 1.00E+00 1.62E-02 1.61E-01 55 328 "ACADM,AGT,SEMA4G,TMEFF1,WASF1,PTBP2,LDB2,LARGE1,SOCS6,CPS1,CYBB,ARMCX2,HEPH,GOLT1B,SEMA3D,PCOLCE2,PIPOX,NRN1,ARMCX1,FDFT1,FGF13,EVL,ALDH1L1,GRIK5,GSTM5,GSTT2,HP,JAK2,MATN2,MEST,MYCN,NNAT,PKM,KCTD15,LRP12,PTN,PTX3,MORC4,SATB1,SH3GL3,ST6GAL1,SLC12A2,SMARCD3,PDZRN3,RBM34,PDZD2,SP4,SYNE2,TACC1,FRYL,TRO,TRPS1,TST,TTC3,RPRM" Coexpression M4224 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h versus the untreated cells at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.62E-02 1.61E-01 36 193 "ABHD6,ADORA1,USP35,EPB41L5,ZFYVE28,NRP2,CA4,VXN,ASIC3,FAM19A5,CSF1,ADGRV1,DLC1,FREM1,GGT7,GPR12,LRRTM1,ZFYVE27,MEST,IGSF11,PDE4A,MBOAT7,PKIA,SLC26A11,NCR3LG1,PTPRD,TMEM145,PRIMA1,RTN1,TMEM200C,SGK1,NFASC,ADHFE1,TIMP4,CSMD1,REEP1" Coexpression M8285 Genes down-regulated in peritoneal cavity B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.62E-02 1.61E-01 36 193 "RNF150,AMH,AMPD2,MTMR2,LURAP1,CAMK2A,IQCK,KIF19,FARSB,EMX2,LRRC17,TMEM132C,CSPG5,MEGF11,DISC1,HNMT,CFAP126,KCND2,KCNQ3,MATN3,FAM216A,PTPRD,KHDRBS2,ARMC5,TMEM200C,ARHGEF40,SSTR2,SSPO,STAC2,PCDHGB7,PCDHB7,RNF175,VSNL1,CLIP2,PCDH20,NAV3" Coexpression M2142 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.37E-03 1.00E+00 1.62E-02 1.61E-01 28 139 "KCNH8,OSBPL6,SPARCL1,ANK2,DCLK1,B4GALT6,OSBPL3,EDN3,PDLIM5,TRAF3IP2,GAD1,PCDH17,GUCY1A1,ARHGAP36,IFI16,STXBP5,MAP2,HS6ST3,NRCAM,RETREG1,RELN,HSPA4L,ARHGAP26,CLSTN2,NXT2,NACC2,HEY1,FSTL5" Coexpression M18108 Genes both mutated and amplified in a panel of 191 breast tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 21 94 "EP400,MYH7B,ARRB1,DNAH17,ADGRB1,CACNA1G,RIMS2,GOLGA7,VPS13B,ZNF461,FGFR1,AGAP2,GRIN2C,KCNQ3,MYO7A,SAMD9,ZFHX4,PPM1E,RADIL,SULF2,ARC" Coexpression M11749 "Genes up-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183], an inhibitor of the BCL2 [GeneID=596] family proteins." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 11 36 "OLFM1,FLNC,NSG1,STMN2,HBA1,NPTX2,GNG2,PPP2R2C,RTN1,SST,ITM2C" Coexpression M9889 Genes up-regulated in colonic lamina propria cells sorted by CXCR6 [GeneID=10663]: high versus low. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ARNTL,SYNJ1,ARHGEF7,FUBP1,CACNA1I,ASIC3,IQCK,ENTPD4,CST3,GPRASP1,DCAF8,SGSM2,RASGRP1,PHF20L1,GOLGA7,ENO2,ANKFY1,TRMO,RAPGEF6,GFER,MSL3,IL6ST,SLC11A2,QRICH1,PTPN13,SUSD4,ALG9,ATXN7,SCN2B,ELMO2,RCOR3,ANKRD36,DOP1A,VPS13A,PLPPR2,CLDND1,KAT6A" Coexpression M7670 Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes: unstimulated versus Pam2CSK4 (96h). MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ADORA2A,SPARCL1,CASK,CACNB4,ENTPD4,HAPLN1,CRY2,NCOR2,CLIP3,CSNK1E,KIAA0586,ZC3H11A,MAMLD1,ZNF391,FOXO3,INPP5K,GCK,FAM107A,GUCY1A1,KLHL23,MKLN1,MMP17,NF1,NOVA2,PFKFB4,GPSM2,ING3,PPARA,SBF1,SCN7A,WDR47,TAF6,DNMBP,TP53BP1,TPM1,NR2C2,RNF103" Coexpression M7177 Genes down-regulated in B lymphocytes from cord blood: naïve versus transitional CR2 [GeneID=1380]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABHD6,FGD2,APAF1,ST3GAL5,SPAG9,QKI,ARHGEF6,RCAN1,GOLGA7,STARD3NL,SRRM1,FCGR3A,SPECC1,GATM,MALT1,KDM2B,SLC2A6,RBPJ,FAM69A,ITGAM,GPR155,ABCB1,PRKCB,PTPRE,KCNIP3,FNIP1,SULF2,SYPL1,SLC44A1,CBX5,TMPO,TNS1,TPM2,EIF4ENIF1,AMZ1,EVI5,NELFE" Coexpression M9002 Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg1 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "AP2A2,FGD2,GAS7,CACNA1I,ENTPD6,ZBED1,DCLK1,ASIC3,CHN1,CHN2,TPP1,OSBPL3,CST3,INTS1,IP6K1,C2CD2L,ABCC5,GABBR1,SCIN,LMO2,MAN2A2,MEF2C,MX1,ZNF862,PLCB2,WBP1L,PTPRH,RIPOR1,RNASE1,ZNF671,SEC14L1,ARFGAP1,TSPYL2,LHPP,GORASP1,MTCH1,PLSCR4" Coexpression M3971 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "APAF1,ASPA,ADAM23,ABCG2,SLC4A8,HINFP,CSF1,DNM1,RASGRP1,RABEPK,AMOTL2,FLNC,TRAF3IP2,SCIN,SMAD1,MEF2C,MPP2,GPSM2,USP47,RBBP8,LRRK2,FOXRED1,SH3BP2,ARX,CPEB3,FNDC3A,PEX26,KBTBD4,DBNDD2,SSPO,RGL1,STXBP1,FBXW11,TCF4,MTMR14,C9orf85,TFIP11" Coexpression M5893 Genes important for mitotic spindle assembly. MSigDB H: Hallmark Gene Sets (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABR,BIN1,CDC42BPA,APC,SHROOM2,ARHGDIA,MARK4,DST,ARHGEF7,WASF1,PRC1,ARHGEF2,TAOK2,DOCK4,DOCK2,TUBD1,EPB41,EPB41L2,PDLIM5,RAPGEF6,SEPT9,CNTRL,GSN,SYNPO,MID1,NF1,CLIP1,CCDC88A,CDK5RAP2,SPTAN1,STAU1,CLASP1,TIAM1,TRIO,TSC1,CLIP2,RICTOR" Coexpression M7490 Genes up-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "EMILIN3,MTUS1,PI16,CA12,CD86,MS4A7,LY86,CCDC151,CNN3,CSF1R,CYBB,DUSP9,EGFR,RASA4,SLC43A2,IGSF6,TLR7,OLFM1,B4GALNT1,IRF8,KCNQ3,KIFC3,PIK3AP1,TM6SF1,DIRAS2,ATP8B4,SGSM1,DGLUCY,SATB1,SPTAN1,TCF4,KIAA0930,TRPS1,ZIC1,KCNT2,SIGLEC10,PLD4" Coexpression M3461 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from adult blood. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ATP1B3,ST3GAL5,ARHGEF7,LDLRAD4,SLC25A14,CD38,CLGN,COPB2,MYL6B,MAGED1,ARHGAP32,DBI,JAKMIP2,EXOG,MED12,E2F5,EGR3,ARMCX1,FECH,TMEM164,SMC2,GUCY1B1,ACOT7,IDH3A,MKLN1,PSMA6,TMEM231,CEP97,ERI2,RIC8B,RMI1,SLA,CDK19,DNMBP,CBX5,TP53BP1,GORASP1" Coexpression M387 Genes up-regulated in 4 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CLK4,ADCY6,SORCS2,ALCAM,PARG,FUBP1,CNN3,RBM39,YTHDC1,SLC12A6,TLR7,ST3GAL6,UBE2E3,RAPGEF6,ZNF638,KAT7,MUM1,BACH2,GABARAPL2,SEPT4,PRODH,C1orf54,PCMTD2,SATB1,MYCBP2,SPP1,SAMSN1,AGTPBP1,TCF12,SIRT1,ACTR6,METTL3,TRIO,TTC3,TUBB2A,RNF103,JMJD1C" Coexpression M7099 Genes down-regulated in neutrophils treated with CSF2 [GeneID=1437] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "RALGAPA1,APC,CHID1,EIF4G3,ATP2B2,CARS,ZMYM4,TBRG4,EPS15L1,CNRIP1,CS,PDE4DIP,SACS,CDON,CALCRL,CHST15,FLT1,PSD2,GAA,FAM120B,ERAP1,TDRKH,CLASRP,MYO5A,NFE2L2,POLR2F,PTCH1,CCDC82,DCUN1D2,SATB1,SULF2,ZFP90,BHLHB9,ELP5,DHX33,PHTF2,LAS1L" Coexpression M9640 Genes up-regulated in CD4 [GeneID=920] T helper cells (4h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ACTN1,KDM5D,PARG,CASK,BACH1,BMPR1B,CACNA1A,CD86,TBRG4,AATK,CSF2RA,IST1,HEPH,GSDME,CASP8AP2,RCAN1,TSPAN5,EIF4G1,MRPL37,FCGR1A,FAM49B,CIT,AGFG1,JAK2,KCNK3,MEIS1,MEST,RPE,SARS,SLC11A1,SOX11,DNAJC9,AKTIP,PARD3,MKRN3,ZFAND5,HNRNPA3" Coexpression M4094 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG2,ADORA1,HACE1,ST3GAL5,CBLN1,METTL6,SEPT7,NOG,ABCG2,FHL5,CNN3,TBPL1,PDCD6IP,EDNRA,PHC2,EBI3,SRPK3,SLC37A3,TNRC6A,LNX1,DIDO1,IRF8,INSM1,KITLG,NDP,SH3KBP1,PTPRE,MCMBP,PEX26,GKAP1,RGL1,TAL1,FBXW11,TBL1X,SYNPO2,RTN4,ZDHHC20" Coexpression M9405 Genes up-regulated in peripheral blood monocytes (PBMC): healthy donors versus patients with HCV infection. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CC2D2A,CDC14B,PTCH2,CCNT1,TPP1,FAM171B,EGFR,FGF13,CPLX2,FAM69A,GPR155,MAT2A,NINJ2,PURG,POU6F1,TTC13,ROGDI,NUDT11,LRRK2,ZNF354C,RASA3,EPN2,SLC22A4,MAST1,INTS9,SNCA,LMBRD1,ZC4H2,PLCB1,TPCN2,C18orf54,HEY1,TSN,TUBB2A,ZNF23,ZFP41,IFT88" Coexpression M7432 Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ACTN1,AXIN2,CARNS1,AMPD3,ARHGEF10,KIAA0040,PITPNC1,DMTF1,RASGRP1,RASGRP2,MEX3B,GSN,FICD,L1CAM,MATK,SRSF12,P2RX7,SERPINI1,PTPRE,RASGRF2,ATP8B4,ZNF354C,SCP2,FAM102A,DZIP1,SLC14A1,ATF7IP,TET1,SP4,MYCBP2,ARHGAP26,SYNE2,TBCEL,ARHGAP9,SGK3,ITM2C,KLHDC1" Coexpression M4672 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "TMCC3,AXIN2,TRMT9B,ZFAT,FAM189A2,CRMP1,CSNK1G3,SEC14L5,RIPOR2,YTHDC1,CHRDL1,NYAP1,RASGRP2,UBE2E3,CAMKK2,ARFIP1,GFER,MUM1,GABARAPL2,INPP5B,STMN1,GPSM2,SLC25A23,PSAT1,MTMR10,RPE,CCDC112,TMCC1,ERBIN,TTBK2,SULF2,RHBDL3,RGMB,PPIL6,UPF3A,PARP11,FRMD6" Coexpression M8298 Genes up-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "AMT,CDC42BPA,STX16,SPAG9,FOXN3,PPT2,CREM,RBM39,PPP6R2,SGSM2,DNAJB6,TENM1,SH3YL1,ST3GAL6,FCGRT,FGFR1,SARAF,KAT7,ITPKB,MXI1,NUCB2,OCRL,PAX6,PDE4B,PLCD1,MINDY2,SNRK,RPS20,RASA3,SGK1,SYNE2,MCF2L,TPM2,NR2C2,TRIO,TSN,TUBA1A" Coexpression M6060 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus TGFB1 [GeneID=7040] and IL-12 (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CLK4,ALCAM,MADD,CDK13,EIF4G3,STX16,ARHGEF7,RAB29,CAPN3,ARMC8,NCOR1,HDAC4,KIAA0586,ZBTB24,HIPK3,PLXNC1,SRRM1,FDFT1,ATP5PD,VTI1B,GALC,CBX1,PRUNE2,GRM8,LIG4,NFYA,OLA1,PLCB2,PID1,DPF2,TRA2B,WDR47,PIK3R5,EIF4ENIF1,VAV1,ACTR3B,FXR1" Coexpression M7516 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus non-Tfh cells with SH2D1A [GeneID=4068] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ADD1,ADD2,WDR35,EPB41L5,PLA2G4C,BLM,NFS1,KYAT1,TBRG4,BAG4,GAPVD1,ALKBH8,RCAN1,OPTN,PLXNC1,TNK2,EPB41,STX2,SCML2,FECH,DHRS4,GRB10,IBA57,GPR155,MIA2,COMMD5,SAMD14,CEP41,EPDR1,GDPD1,SH3TC2,ZDHHC14,SLC12A4,HIF3A,ZMAT3,BEX4,BCL2L13" Coexpression M9073 Genes up-regulated in memory CD8 T cells from brain: ITGAE- [GeneID=3682] versus ITGAE+ [GeneID=3682]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ADRB2,CASK,ALDH7A1,ST3GAL5,IGDCC3,CST3,EBI3,RASA4,SEMA4D,TPK1,INPP5K,ACSS1,GDF9,WASHC2A,GSTM5,IGF1,KIT,KTN1,MATK,MBP,MX1,NELL2,NF1,SERPINI1,POU6F1,PRKCB,MAPK10,CLIP1,RYR3,RASA3,GKAP1,TEX2,PHLDB1,SYT5,LRRC8A,SMARCAD1,RTN4" Coexpression M5195 Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ASIC1,ACTN1,AMPD2,APOC2,LDB2,SLC16A4,P2RX6,ENTPD2,CHRNA4,CRHBP,ZNF804A,FBXL5,SPOCK3,ENO2,LRRC17,ZNF391,FOLR2,GFER,GNAL,STON1,NXPH3,SMAP1,KCNB1,KIF5A,KIFC3,KTN1,MBP,ADAM11,RPE,EPN2,LIMCH1,SP4,ANKRD28,SMG6,DNAH7,RUNDC3B,VSNL1" Coexpression M4720 Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ESYT2,NRP2,CFLAR,IL33,SPAG9,MAP4K4,WHRN,ABCG1,PDE4DIP,MAMLD1,GOLT1B,EGR3,LINC-PINT,HSD17B14,DENND4A,RPS6KC1,SPSB4,IQCG,TOX3,TPPP,GRB10,GUCY1A1,GUCY1B1,MGC16275,NIM1K,IL12A,TTYH2,NFE2L2,OXTR,SCHIP1,NUDT11,FNDC3A,SLC2A5,ANKRD28,ZFPM2,TPM2,ADAMTS10" Coexpression M8324 Genes up-regulated in follicular helper T cells: BCL6 [GeneID=604] high versus BCL6 [GeneID=604] low. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CDC42BPA,PLA2G4C,CADPS,NCOA1,BID,TPP1,PPP6R2,USP6NL,CYBB,MATR3,SNAP91,SGSM2,TENM1,EIF1,ST3GAL6,SARAF,SEPT9,SRCAP,STMN2,KAT7,HAS2,PADI2,ITPKB,NUCB2,PDE4B,PLCD1,PLIN1,POU6F1,PCMTD2,RASA3,NSFL1C,SYNE2,TRIM2,TPM2,TSN,TUBB2A,TUBA1A" Coexpression M4559 Genes up-regulated in comparison of adult thymic progenitors versus adult DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "SPOP,FGD2,N4BP2L1,CD86,B4GALT6,CSF1R,MYADM,YTHDC1,EBI3,PLXNC1,TLR7,SPECC1,IQGAP2,GCNT2,PRDM5,MAP4K5,IRF8,LMO2,MEF2C,MEIS1,MYCN,NUCB2,RETREG1,PPP3CA,PTPRE,SLC25A36,ROBO1,DGLUCY,PEAR1,FHOD3,ST6GAL1,DZIP1,TAL1,ZMAT3,TRIO,ZBTB14,GDPD5" Coexpression M3251 Genes up-regulated in comparison of Ig isotype switched memory B cells versus plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG3,CDK13,ZSCAN18,NCOA1,BTK,PTBP2,SYNGR3,SMARCAL1,USP6NL,CYBB,ARHGAP24,ZFYVE16,MAML1,GIT2,PTK2B,TRAF3IP2,RAPGEF6,SEPT9,BTN2A1,INPP5B,PIK3R1,SNX10,PTK2,ZSCAN32,SLC25A36,FAM192A,PEX26,WDR47,BTBD7,KDM3A,CEP68,ZMAT3,TP53BP2,LAT2,ZBTB14,ATP6V0E2,FIP1L1" Coexpression M3163 Genes down-regulated in comparison of Th1 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ZNF687,DPY19L3,GPC2,CCK,MAP4K4,AKAP7,HINFP,MFSD10,VPS26C,EXTL2,ACSL4,FECH,SPECC1,SLC2A6,DDX19B,CREG2,PAXBP1,MITF,N6AMT1,RTL5,DRAM2,DEF8,PTPN13,CCDC82,LRRK2,NCBP3,PDZRN3,SYPL1,PCDHB15,TIAM1,C9orf85,SLC35A4,CCDC136,ZBTB14,TUBA1A,FAM219B,RSPRY1" Coexpression M5096 Genes down-regulated in comparison of naive CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "APBB2,N4BP2L1,LDHD,BAIAP3,PTBP2,USP2,DIS3L,WDR20,DLX1,YAF2,KMT5B,ASB3,CERCAM,EVL,FYB1,ZMAT1,DIDO1,SLC2A6,HMGCR,LSS,P2RX7,PPP3CC,RDX,SCAF8,WDR47,NAPB,CPEB4,USP33,KLHL7,GPRIN3,ACTR6,KCNE5,TST,BCL2L13,CLIP2,ZFAND5,EMSY" Coexpression M7212 Genes down-regulated in mouse embryonic fibroblasts (MEF): control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "FGD2,ARMC12,GAS7,TNRC6C,CASK,BTK,SGCE,HIP1R,CBS,SLC16A4,NDST3,CPNE6,CNN3,SH2B1,RGS6,SEC16A,EBF1,RASA4,ERBB2,DNAJC27,SESN1,GHR,RUNDC3A,CIT,MYLK2,KCNB1,LIFR,SMAD9,TREM2,WBP1L,ZDHHC14,KLHL11,SH3BP2,CPEB3,DZIP1,ITGB3BP,CFAP298" Coexpression M7502 Genes down-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper). MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "TMCC3,OSBPL8,CDC14B,NCOA1,CCPG1,RIPOR2,ARMCX2,TMCC2,SLC12A6,KMT5B,F5,CHST15,MED12L,KHDRBS3,GLYR1,NCKAP1L,STMN1,MEIS1,NME4,CNTLN,RNASEL,CCDC25,CHD9,ANKRD6,ATF7IP,CEP68,PLCB1,SMG6,DMXL2,TNS1,TP53BP2,TRIO,PARP11,AMN1,DOCK8,KLHDC1,RNF146" Coexpression M4449 Genes up-regulated in comparison of memory IgG IgA B cells versus plasma cells from bone marrow and blood. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "BIN1,PDE8B,SEPT7,CNOT8,QKI,LY86,PPP1R16B,GPRASP1,RIPOR2,GIT2,CASP8AP2,PDCD6IP,FRY,RASGRP2,ATP6V1H,FYN,GABBR1,SEPT9,ARFIP1,CLASRP,ELOVL5,NACA,SNX10,PMP22,PRKACB,PRKCB,PIGG,MARCH1,RAP1GDS1,ATF7IP,POGZ,SYPL1,PUM2,XPO1,KAT6A,PHTF2,SENP7" Coexpression M7873 Genes down-regulated in macrophages: LYVE1+ [GeneID=10894] versus LYVE1- [GeneID=10894]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CBFA2T2,STOML1,CLTB,QKI,SULT4A1,CRMP1,HAPLN1,CRYBB1,GALNT9,DGKG,SPOCK3,DNAH9,EDN3,HVCN1,SDCBP2,GALNT15,RABL2A,DDX19B,LSAMP,MGAT3,MYH3,P2RY13,NF1,P2RX7,PCDH8,FSD1,FAM184A,UBR7,SCN2B,ST6GAL1,NLGN1,SLC4A3,SIRT2,ADHFE1,SLC37A2,P2RY12,FAM219B" Coexpression M363 Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "TMCC3,ADRB2,BEND6,AP2A2,KALRN,PTBP2,CD86,CNRIP1,PNPLA8,RIPOR2,DPH1,SNX29,GPHN,SCML2,MEX3B,FOXO3,PSIP1,MIER3,HLF,SLC35G1,KIF2A,MN1,PDCD2,RETREG1,CNTLN,TUG1,ZC3H14,DZIP1,KANSL3,UHRF1BP1L,CDK19,PBLD,RICTOR,ZSCAN26,SLC30A4,KAT6A,ADAMTS10" Coexpression M6633 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] and 180 min stimulation of: LPS versus IL10 [GeneID=3486] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABR,C3orf14,ELFN2,NME5,BBOX1,HCN2,CD38,WHRN,CRHBP,NCOR1,ABCG1,SEC14L5,LYPD1,DYNC1I1,F8,SPECC1,PRELID3A,GALNT15,IP6K3,HPGDS,GLUL,CREG2,MITF,GDPD1,PTPRN2,ZFP30,CNKSR2,SLC8A1,MBD5,SP4,UHRF1BP1L,CLASP2,PRRC2C,SLC37A2,GPR161,CDH22,DCBLD1" Coexpression M6424 Genes up-regulated in monocytes in response to M. tuberculosis 19 kDa lipopeptide: 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "TMCC3,AP1M1,DDR1,ENTPD6,ZNF445,COX4I1,CD99L2,GPHN,EVL,TPK1,MALT1,HPGDS,MSL3,PSIP1,MSL1,IL6ST,INPP5B,PIK3AP1,MEIS1,KCTD6,ADAM22,PRKACB,ROGDI,BEND5,RGS12,CLIP1,CASC3,CCDC88A,SULF2,ATMIN,NSD1,CYB561A3,SMUG1,SGK3,UGT8,TMEM178A,ITM2C" Coexpression M5507 Genes down-regulated in comparison of macrophages versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "SPOP,SLC2A11,N4BP2L1,ARHGEF7,SLC25A14,CBLN1,ARHGAP33,LOC730101,AKAP7,ZNF337,HEYL,TNK2,EVL,USP21,FYN,GABRA3,RAPGEF6,BTN2A1,HSPA1L,KCNN3,LSAMP,MYH3,DPY19L2P2,PCDH8,PDE4B,POLG,PTCH1,TUG1,ZCWPW1,SAFB,GALNT10,CDK5RAP3,TSPYL2,POGZ,MMS19,MPPE1,KAT6A" Coexpression M7986 Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ARNTL,BMP7,CH25H,USP2,ENTPD2,COL9A3,IGDCC3,CRMP1,ABCG1,GSDME,GUCD1,REEP2,MED12L,AFF2,SPECC1,GABRG2,MAP7D2,ADAMTS6,KCND1,KCNN1,NOVA2,NTRK3,PDE3A,PTPRB,SGSM1,ABLIM3,ZNF423,STAC2,NR2C2,ZKSCAN5,FLRT2,P2RY12,ZFP37,KCNT2,AGMO,KCNAB1,RNF146" Coexpression M5124 Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "AP2A2,C1QTNF1,APAF1,KCNAB2,APBB2,NCOA1,AP1M1,HOMER3,RGS6,CST3,MYADM,DOCK2,EIF4G1,MED12L,ERGIC3,CHL1,GFER,DHRS4,MAN1B1,KCNH2,MBP,MEIS2,MID1,SFR1,SCHIP1,PTPRG,PTPRN2,PBRM1,RPE,TNFRSF19,ARX,KIF16B,TET1,SOX11,MPRIP,EIF4ENIF1,ZFP37" Coexpression M4978 Genes up-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ADRA1B,LGR5,MADD,ASIC3,SPOCK3,SEZ6L2,ETV1,PRELID3A,TDRKH,STON1,GRB10,CACFD1,KCNJ16,KHK,L1CAM,PALM,PCSK5,ZFYVE21,KCTD15,EPB41L4B,DIRAS2,PTPRD,RGS4,SETD5,MAPK12,SCN2B,ZFP2,SH3GL3,MYH15,APOM,PHLDB1,SYT5,TACR1,SMG6,ZKSCAN5,TUBB1,NDRG4" Coexpression M9792 Genes up-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "SYS1,UNC5A,BEND6,TRMT9B,CFLAR,BMP7,METTL6,CD38,CFL2,RASGRP1,ERBB2,MRPL10,FCGR1A,SUCO,AGAP2,FYB1,GPD2,FICD,HP,LSAMP,CHIC1,MSR1,MX1,IDNK,NINJ2,ETFRF1,PGAM2,DPF2,MAP6D1,COPZ1,RGL1,PCDHB15,CYB561A3,HIRA,UBC,SPHK2,NLRP3" Coexpression M6261 Genes down-regulated in CD4 [GeneID=920] T cells: healthy versus CLL (chronic lymphocytic leukemia)l. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "AP2A2,PITPNM2,AMPH,ARMC12,ZFYVE28,BLM,MTMR3,CAMK2G,CRHBP,CSF1R,TIAM2,CELSR3,ELN,TBC1D16,ADAM28,USP19,DBF4,KCNJ5,SRSF12,GLIPR1L2,GPR85,NALCN,RELN,PTPRG,SUGCT,CSRNP3,LGI3,KDM4B,TSNAXIP1,SPART,FAM208A,KIAA0930,DNAH7,BEX4,CA14,CLEC2L,URM1" Coexpression M8205 Genes up-regulated in macrophages: tumoricidal versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG3,LTBP4,SLC4A4,ATP2A2,ALDH7A1,CCK,P2RX6,CFL2,RAB28,CNN3,DCTN1,SEC16A,ANKRD46,C8orf37,ETV1,EYA1,ST3GAL6,PCYOX1,FOXO3,JKAMP,GHR,FICD,PTOV1,PGAM2,SCHIP1,SLC25A36,ZC3H14,SLC6A8,SLC12A4,GKAP1,KDM3A,TBCEL,HEY1,CA14,UBE2H,ZNF23,DPF3" Coexpression M4136 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CLK4,APAF1,EIF4G3,SRSF11,LHX2,RAB33A,PUM1,TM9SF4,MYEF2,RUSC2,DLX1,DTNB,RASGRP1,CALCRL,CD320,TRAF3IP2,ITPKB,JAK2,PAXBP1,P2RX7,GLIPR1L2,GPR85,GPSM2,EPDR1,PTK2,USP47,RFX3,PCMTD2,SLC11A1,KBTBD4,SLC22A4,TET1,FBXW11,SMG6,METTL3,VAV1,SOCS4" Coexpression M6563 Genes down-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus AM580 [PubChem=2126]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG3,ARHGEF1,PITPNC1,SLC12A6,RASGRP1,TNK2,CALCRL,MEX3B,HVCN1,SDCBP2,ACSS1,SPACA9,IRAK3,INPP5B,ITGA7,PDCD2,ABCB1,PIK3R1,SLC25A23,PLTP,SEPT4,PRKACB,PTPRE,RNASEL,SATB1,SUPT20H,RASA3,SGK1,FAM102A,MAST1,CABCOCO1,SULF2,MGRN1,PIK3R5,ZSCAN26,SNX14,KLHDC1" Coexpression M4440 Genes up-regulated in comparison of naive B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "C1QTNF1,AMT,FAM131A,DDR1,LY86,GPRASP1,ARHGAP32,DCAF8,TBC1D5,KLHL3,ABCC5,SCML2,CORO2B,ANKFY1,GABBR1,CHL1,RAPGEF6,IRF8,ITPKB,ZNF862,RETREG1,STRN3,POU6F1,MTMR10,RADX,ZNF532,SLA,INTS9,PEG10,CDK19,TSPYL2,CEP68,TTBK2,SIN3B,TRPS1,KAT6A,ACTR3B" Coexpression M7878 Genes down-regulated in B cells: light versus dark zone. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG3,ADCY6,PLEKHH1,PWWP2A,MTA3,GPRASP2,BMP7,DGKI,IQCK,SMARCAL1,FAM169A,CTH,GIT2,ARMCX4,DNAJB6,PLEKHA1,SH3YL1,ST3GAL6,TXNL4A,C2orf72,KIT,MID1,NEFH,PDE4B,TRHDE,TUG1,TMEM255A,ROBO1,TRA2B,ST8SIA1,WDR37,SLC8A1,ZKSCAN3,ZFP1,LRRC8A,ZFP37,SMIM8" Coexpression M6636 Genes down-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus IL6 [GeneID=3469] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "MTUS1,CCAR2,ASIC3,TAOK2,TBPL1,RNF14,CD99L2,RCAN1,SEZ6L2,EDNRB,FAM198B,AKAP3,GABRA3,ERAP1,ADAM28,SLC2A6,MSR1,CDK18,RETREG1,SLC25A23,KANSL1,RPS6KA2,BTBD3,FNBP1,ARHGAP26,SPTB,ITPRID2,STXBP1,DNMBP,TBL1X,ZMAT3,AKTIP,TIAM1,SPIRE1,SLC30A4,SLC38A1,ST7" Coexpression M9657 Genes down-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "PPFIA4,BMPR1B,CAMK2A,CD86,LRBA,B4GALT6,RAB33A,MAP4K4,CNGA3,RNF14,AATK,DNM1L,ATP6V1H,ST6GALNAC3,CPLX1,TUBA8,SRCAP,TXNL4A,IDH3B,ITGA7,MX1,FAM216A,PRKAR1B,BCAS3,AP1AR,SLC22A4,SOX11,SLC44A1,NPL,TSC1,UBE3A,LGI4,MKRN3,ZSCAN26,SLC30A3,TUBA1A,FRMD6" Coexpression M5169 Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (5 worms/well). MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABCF1,KDM5D,BARD1,CCNH,ARHGEF1,CLTB,CNN3,PCYT1B,ZNF337,MATR3,B3GAT3,DOCK2,SEMA3D,OPTN,ATP6V1H,SARAF,FYN,TCERG1,RNPS1,ITPKA,KIF2A,MAPK3,PRPH,NDUFS7,SNRK,RPS6KA2,SARS,CNKSR2,IQSEC2,ST5,TAF9,FBXW11,CLASP1,KAT6B,TSC2,CLDND1,RTN4" Coexpression M7640 Genes up-regulated in memory CD8 T cells: 1' versus 3'. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABR,ASIC1,OGT,SYNJ2,CBFA2T2,ARHGEF2,LETMD1,NCOR2,ABCG1,PHC2,ST3GAL6,CHST15,FCGR3A,FOXO3,KAT7,HSF2,MITF,PIK3R1,PLEC,WBP1L,RAP1GDS1,RGS12,RPL15,RXRA,ZNF821,FAM214B,SLC22A4,COA1,KDM3A,MPRIP,DNMBP,TCEA1,TCF12,USP22,RUSC1,CLIP2,ZFAND5" Coexpression M5720 Genes up-regulated in comparison of NK cells versus total splenocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "AS3MT,RNF157,PKP4,ZBTB10,BAIAP3,PHACTR3,GPSM1,ARMCX2,TSPAN5,EYA1,OLFM1,JKAMP,IQGAP2,ARFIP1,SPACA9,GSTM5,HSPA1L,KIFC3,STXBP5,SMAD1,AFDN,ABCB1,PTPRE,USP47,TRIM68,ERI2,ATP8B4,WDR37,FAM81A,TET1,SMARCD3,SP4,KLHL4,ARHGAP9,GPRIN3,PLSCR4,GAN" Coexpression M6193 Genes down-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "RNF157,SYT13,CDC14B,DDR1,ARHGAP24,LONRF1,DNAL1,RHOBTB1,DMPK,CD99L2,SLC43A2,ETV1,TMEM107,TPPP,SHISAL1,LIG4,AFF1,MYO9A,PLCD1,PMP22,SEPT4,MAPK10,CNTLN,PTPN13,PTPRE,RBBP8,MSANTD2,PPM1E,IQSEC2,SEPT8,TMEM150C,TCF4,THRA,CDK20,VLDLR,ZNF711,GDPD5" Coexpression M5216 Genes down-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ASIC1,ADD1,OSBPL1A,APOC1,STX16,ST3GAL5,IL33,CAST,USP6,RCBTB2,CHN2,CNOT8,ABCG1,PPP6R2,DAPK1,FBXL5,FOLR2,LILRA2,KCNB1,LMO2,MSR1,PALM,PRKACB,PRPSAP2,RXRA,MAPK12,EPN2,PEG10,ARHGAP26,IQCE,USP22,SYNE1,BEX4,TPM1,RUNDC3B,CLIP2,EVI5" Coexpression M8675 Genes down-regulated in monocytes (24h): muramyl dipeptide [PubChem=11620162] versus muramyl dipeptide [PubChem=11620162] and M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "CLK4,ACTN1,CDR1,COX4I1,SEC31B,DZIP3,USP6NL,KLHL3,CEP85L,ARMCX1,RACK1,FKTN,NBEA,FYB1,RAB30,MSL3,IL6ST,ZNF667-AS1,MEST,MYH3,NELL2,DNHD1,ETFRF1,PCSK5,ZNF655,SMIM7,ELP2,FBXO11,MBD5,RBM34,NSFL1C,TAF9,FRYL,ERCC6L2,NR2C2,TTC3,CCDC136" Coexpression M9692 Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 60h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ALCAM,PTCH2,CFLAR,CA12,P2RX6,CLGN,B4GALT6,WDR20,CASP8AP2,RCAN1,COPS4,PTK2B,SPECC1,SARAF,GATM,PPARGC1A,LYVE1,GNAO1,CNTRL,KHK,MAP6,MIA2,MYO5A,NDP,NF1,MAGEL2,PPP3CA,PTPRE,AP1AR,SARS,ATXN2,KDM3A,NEK4,ANKRD28,AKTIP,MKRN3,ZFAND5" Coexpression M7746 Genes up-regulated in macrophages with NR3C2 [GeneID=4306] knockout: untreated versus corticosterone [PubChem=5839]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ACADM,ARRB1,RAB29,CAMK2G,DCAF8,DCTN1,CD99L2,TOM1,EZH1,TAOK3,FOXO3,DHRS4,KDM2B,POLL,IL6R,MBNL1,MXI1,P2RX7,PURG,PRKACB,DEF8,SNRK,ZDHHC4,FBXW7,FAM192A,SEC14L1,ZFP30,FBXO11,ANKRD28,PJA1,TNS1,TTC3,TUBB2A,RTN4,JMJD1C,ADAMTS10,FRMD6" Coexpression M6943 Genes down-regulated in B lymphocytes: PL2-3 (Chromatin IC) versus anti IgM and CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NDRG2,APLP1,GPR146,MTMR3,CAST,SPAG9,TMEM184B,HECTD1,LETMD1,PITPNC1,RASGRP1,YAF2,C3orf18,NRN1,ACSL4,TMEM107,FYN,GALC,SEPT9,AFF1,AFDN,MXI1,SMOX,DRAM2,POU6F1,CASTOR1,RAP1GDS1,REV3L,FNIP1,KDM3A,TEX2,AGTPBP1,USP22,HEY1,TP53BP2,C9orf85,TMEM237" Coexpression M8313 Genes down-regulated in activated T cells: CD4 [GeneID=920] versus NKT. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "NCOA1,CALM1,ENTPD6,TPP1,SEC31B,RBM39,SGSM2,DNAJB6,TNK2,EIF1,RASGRP2,SH3YL1,TAOK3,ST3GAL6,FCGRT,SARAF,FYB1,TRAF3IP2,KAT7,IL6ST,ITPKB,AFF1,MXI1,NUCB2,PDE4B,PDE4D,SNRK,SATB1,SGK1,KDM3A,NSFL1C,MGRN1,TPM2,TSN,TSC2,TUBA1A,CIAPIN1" Coexpression M8209 Genes up-regulated in germinal center B lymphocytes over-expressing: PRDM1 [GeneID=639] versus Epstein-Barr virus protein LMP1. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ABR,SRPX,PPFIA4,APOC1,APOC2,USP2,SCARB1,CPNE6,LY86,COL11A2,CSF1R,PDE4DIP,CYBB,GPRASP1,TOM1,ABCC5,EDN1,RASA4,SRPK3,STX2,TLR7,FCGR1A,ACSS1,STARD3,NCKAP1L,HMGCL,CYBC1,RXRA,SIRT2,FNBP1,RGL1,ICAM5,BEX4,ELP5,TSC2,KLC2,PLD4" Coexpression M9136 Genes down-regulated in CD4 T conv: control versus over-expression of FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ADD1,DOCK11,BACH1,CBR1,CD38,ZNF445,CCPG1,CNN3,ABCG1,RIPOR2,ARHGAP24,TBC1D5,USP3,MED12,RCAN1,RASGRP2,TLR7,FOXO3,ZNF274,IRAK3,KCTD6,MXI1,NUCB2,SERPINI1,RDX,RNASEL,PCMTD2,MAPK12,SATB1,SGK1,ATF7IP,MYCBP2,CYB561A3,TK2,ZKSCAN5,KLHDC1,GAN" Coexpression M8734 Genes up-regulated in T cells: control versus IL2 [GeneID=3558] stimulation for 17h. MSigDB C7: Immunologic Signatures (v6.0) 1.38E-03 1.00E+00 1.62E-02 1.61E-01 37 200 "ACADM,OSBPL1A,FAM135A,MAP4K3,APOC1,C5,CBR1,CD86,CHN2,LY86,CNRIP1,PREPL,CRHBP,OSBPL3,RHOBTB1,SNX29,FAM13A,MRO,TLR7,ARMCX1,FECH,ZBED3,IQGAP2,GGTA1P,GPR34,STMN1,MEF2C,AMZ2P1,TREM2,PFKFB2,GDPD1,VPS13C,REV3L,RPS6KA2,PLCB1,TAF9,TNS1" Coexpression 18410693-TableS12 Human Leukemia_Kiiveri08_100genes_MLLParallel GeneSigDB 1.39E-03 1.00E+00 1.63E-02 1.61E-01 15 58 "AK2,VAT1L,MATR3,CPEB2,PLXNC1,PAN3,SH3YL1,SMAD1,PIK3AP1,MBNL1,MEIS1,MTMR10,SYNE2,TCF4,PCDHGC5" Coexpression M9752 Genes up-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.39E-03 1.00E+00 1.63E-02 1.61E-01 57 343 "MTA3,GPRASP2,EP400,PKP4,APBA2,GAS7,MPDZ,SLC25A14,TIGD7,FAM19A5,BOC,DNAL1,YTHDC1,MFAP3L,E2F6,ASB3,RASL12,ARMCX1,KAT8,SLC37A3,TUBGCP4,GGT7,COPS8,RASSF8,USP51,AGFG1,DHX35,METTL21A,LAMA2,MEST,ZNF92,BEX5,SLC11A2,RETREG2,RAD17,RBBP6,TMLHE,YY1AP1,ELP2,RPE,CDK5RAP3,MTERF2,TTC17,SNRPN,SPATA7,ZNF621,ZFP90,BHLHB9,BEX4,TP53BP1,ZBTB14,ZNF711,ZNF24,ZSCAN26,MFF,ADAMTS9,FIP1L1" Coexpression 18450603-Table3S Human Leukemia_Marcucci08_696genes GeneSigDB 1.39E-03 1.00E+00 1.63E-02 1.62E-01 80 515 "ABR,ACTN1,BRAP,KIAA1211,AK2,ALCAM,ARRB2,NUMB,BID,RAB29,CAST,HIP1R,CD86,MS4A7,TPP1,QKI,CSF1R,CSF2RA,VCAN,CST3,UBXN2A,CYBB,PDCD6IP,ABCC5,EPB41L2,SLC43A2,IGSF6,PRAM1,DLC1,FCGR1A,PRKAG2,ATP5PD,SEC23B,IP6K2,TMEM107,TPK1,USP19,LILRB4,LILRA2,SLC2A6,IRAK3,HNMT,AGFG1,IL6R,INPP1,PIK3AP1,MEF2C,MSR1,NCF2,P2RX7,SNX10,PKM,PILRA,DRAM2,SLC26A11,RIPOR1,MARCH1,HKR1,RNH1,CYB561D1,EMID1,RXRA,AP1AR,SARS,ATXN7,SLC2A5,SLC11A1,SLC14A1,CAMTA2,THSD1,TCF4,DMXL2,TPCN2,ARHGAP9,SIK3,FAM200B,TLR4,NPL,VAV1,NETO2" Coexpression 17880687-Table2 Human Embryo_Heim07_40genes_ChangedBasallyRIP140 GeneSigDB 1.40E-03 1.00E+00 1.64E-02 1.62E-01 9 26 "BACH1,PTBP2,HECTD1,B3GAT3,UFM1,GCNT2,GPD2,ZNF655,FNIP1" Coexpression 17471573-Table2 Human Viral_Santegoets07_103genes GeneSigDB 1.42E-03 1.00E+00 1.66E-02 1.64E-01 20 88 "BLM,DST,SGCE,CAPN3,SCARB1,SLIT2,CASP8AP2,EDN3,EDNRA,EDNRB,FGFR1,GHR,IGF1,ITGA7,KIT,EPDR1,PTN,ADGRL3,ITGB3BP,NETO2" Coexpression M15456 Genes whose promoters were bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and which were up-regulated in comparison of tumor vs normal prostate tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.42E-03 1.00E+00 1.66E-02 1.65E-01 10 31 "CBFA2T2,SEPT7,ARHGAP33,CCDC151,PICK1,PDE4DIP,POM121,L1CAM,GDPD2,MEG3" Coexpression 19755675-TableS6 Human Leukemia_Li09_419genes GeneSigDB 1.43E-03 1.00E+00 1.67E-02 1.65E-01 66 410 "ACTN1,SEMA6A,ALCAM,BCL7A,BID,PROM1,BTK,MTMR3,WASF1,HIP1R,CD38,CDC25B,RCBTB2,LY86,MAGED1,CRMP1,CRYM,LRIG1,ARHGEF10,ARHGEF4,CYBB,RIPOR2,HDAC4,DAPK1,GSDME,RCAN1,RASGRP1,ENO2,EPB41L2,FCGRT,FGFR1,FHL1,UBE2E3,FYB1,IQGAP2,LILRA2,PCLO,GSN,GUCY1A1,ELOVL5,SYNPO,ITPKB,KCNN1,LAMP2,LMO2,MBNL1,MEIS1,MX1,NPY,NPTX2,NUCB2,PCDH9,PDE4B,PKM,SCHIP1,PRKACB,PRKCB,SLA,SLC2A5,FNBP1,RGL1,SYNE2,COBL,TBL1X,BEX4,VLDLR" Coexpression M6716 Genes up-regulated in endothelial cells: B. burgdoferi versus IFNG [GeneID=3459] and B. burgdoferi . MSigDB C7: Immunologic Signatures (v6.0) 1.44E-03 1.00E+00 1.68E-02 1.66E-01 33 173 "NDRG3,MTA3,TBC1D14,KCNAB2,NCOA1,N4BP2L1,BACH1,GPR146,NFS1,ING4,SLC43A2,FCGRT,FOXO3,GALC,GPR162,HPGDS,PRUNE2,COQ10A,KHK,SCAMP5,RETREG1,PTGR2,SEC14L1,MYO18A,ELMO2,ATF7IP,TRERF1,FNBP1,IQCE,TIAM1,TPM1,LAT2,SLC38A1" Coexpression 15297395-SuppTable4 Human Lymphoma_Sriuranpong04_670genes_Epithelium(N)Metaplastic/DisplasticLesions GeneSigDB 1.44E-03 1.00E+00 1.68E-02 1.66E-01 61 373 "ACHE,ADD1,AXIN2,SPARCL1,SPOP,EP400,DDO,CDK10,NUMB,ALDH7A1,RIPK1,MPDZ,BID,ARHGEF7,NFS1,ENTPD6,NPIPA1,B4GALT6,RAB28,FBXO7,MAP4K4,COL9A3,ZNF804A,RHOBTB1,DMTF1,DTNB,ENO2,COQ7,FCGRT,FHL1,SEMA4D,TRIM16,GABRA3,GALC,BRD8,KIAA1958,PTPRT,HSPA1L,KIF5A,LSS,ADAM11,MXI1,MYO9A,NBL1,OGG1,PCDH8,PKD1,PPM1B,KLK6,ATXN2,SMARCD3,MAPKBP1,TRIM2,SIRT1,METTL3,NEIL2,TTC3,VLDLR,VSNL1,ZBTB14,FSTL5" Coexpression M7804 Top 100 probe sets for core-binding factor (CBF) acute myeloid leukemia (AML): contains CBFB MYH11 [GeneID=865;4629] or AML1 ETO [GeneID=861;862] fusions. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.45E-03 1.00E+00 1.68E-02 1.67E-01 19 82 "ABR,BAIAP3,RUNX1T1,CACNA2D2,SIPA1L1,RASA4,NCALD,TPK1,HPGDS,MN1,OGG1,ROBO1,BAALC,STK32B,KDM4B,TRIO,WIPF1,CLIP2,LAT2" Coexpression M12001 Cluster 5 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.46E-03 1.00E+00 1.70E-02 1.68E-01 17 70 "RALGAPA1,PKP4,ZSCAN18,ASIC3,SEZ6L2,SYT17,SLC25A23,SMIM7,SMARCA4,KDM4B,ADGRL3,SIN3B,ZNF34,TSN,PLPPR2,ZFP37,ZNF177" Coexpression M7635 Genes up-regulated in memory CD8 T cells: 3' versus 4'. MSigDB C7: Immunologic Signatures (v6.0) 1.47E-03 1.00E+00 1.70E-02 1.69E-01 34 180 "RNF150,APOC2,USP2,SCARB1,CDO1,SOCS6,DBI,DMPK,CPEB2,DPYSL2,RCAN1,PRAM1,FCGRT,HPGDS,PRUNE2,GSN,ICA1,KHK,KIFC3,LMO2,P2RY13,NME4,PDE4D,ZDHHC14,GAL3ST4,RASA3,CHD9,ST6GAL1,SLC37A2,TMEM9,SGK3,LAT2,PLD4,JMJD1C" Coexpression 15695585-Table3 Mouse StemCell_Zhao05_10genes GeneSigDB 1.47E-03 1.00E+00 1.71E-02 1.69E-01 5 9 "BIN1,SULT4A1,CNN3,PTPRO,SATB1" Coexpression M8814 Genes up-regulated in FoxP3-IRES-GFP: NOD T reg (FOXP3+ [GeneID=50943]) versus B6 splenocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.48E-03 1.00E+00 1.71E-02 1.70E-01 30 153 "ABR,AXIN2,ADORA2A,LTBP4,FAM131A,ARNTL,CADPS,NCOA1,DPY19L3,KSR1,SYNJ1,BAIAP3,NCOR1,PLCXD3,KIF26A,SPOCK2,MFAP3L,DTNB,FRY,TRAF3IP2,IGF1,GPR155,CLDN11,PIK3C2A,PLCD1,PTH1R,SUSD4,PEAR1,ANKRD6,TIAM1" Coexpression M6735 Genes up-regulated in B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.50E-03 1.00E+00 1.74E-02 1.72E-01 36 194 "ADCY6,OSBPL1A,TBC1D14,KCNAB2,GPR146,SYNJ2,LDLRAD4,CA8,CABP7,ZBED1,KIF26A,CHRDL1,MAD2L2,PRKAG2,GAD1,POLL,ADAP1,STON1,HMGCL,INPP1,KIT,MBP,MN1,EXOSC10,PKIA,PTCH1,NUDT11,FAM102A,INTS9,NKAIN2,RGL1,TACC1,NACC2,TNS1,TUBB2A,CLDND1" Coexpression M2728 Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.50E-03 1.00E+00 1.74E-02 1.72E-01 36 194 "ABHD6,OSBPL1A,RASL11B,MTMR2,SGCE,CAST,RCAN1,OPTN,FAM13A,EGFR,ACSL4,FGF1,SCARA3,KHDRBS3,FYN,ERAP1,MALT1,FERMT2,GPR37,GRB10,SLC2A6,L1CAM,CDK18,PDE4D,SERPINI1,MORC4,ZNF331,ANKRD6,PEG10,ARHGAP26,DBNDD2,KLHL7,SYNE2,NPL,TUBB2A,UGT8" Coexpression 17970077-Table3 Human Viral_Uchimura07_17genes GeneSigDB 1.50E-03 1.00E+00 1.74E-02 1.72E-01 7 17 "AMPD2,PPT2,CST3,SPOCK2,DPYSL2,E2F5,FHL1" Coexpression 18593951-TableS2 Human Ovarian_Bonome08_263genes GeneSigDB 1.52E-03 1.00E+00 1.75E-02 1.74E-01 41 229 "NDRG3,APBB2,MARK4,NCOA1,WASF1,NFS1,CLDN10,FOXN3,CRY2,ARHGAP24,SPATA2,SACS,OPTN,AASS,FLT1,ATP6V1H,FYN,GAA,IQGAP2,TMEM8B,BTN2A1,GSN,IFI16,OPA1,PCSK5,PLXNB1,RGS3,EXD2,STK32B,SLC14A1,ATF7IP,DOP1A,SOX11,DOK5,ZHX3,SP4,CDK19,JMJD6,SYT1,DNMBP,NSD1" Coexpression 17533364-TableS3 Human Brain_Lastowska07_548genes GeneSigDB 1.56E-03 1.00E+00 1.79E-02 1.78E-01 55 330 "TBC1D14,CC2D2A,ARRB1,MTMR2,METTL6,ZNF445,MYRIP,CRMP1,HINFP,ARHGAP32,TBC1D5,ALKBH8,CDON,CPEB2,PDCD6IP,MFSD10,ZNF589,TMEM175,MSANTD4,CHL1,CPLX1,RAB30,ADGRA3,RBPJ,THYN1,OGG1,CYTL1,QRICH1,PIGG,RDX,DPF2,RGS12,PBRM1,CCDC82,SETD5,ALG9,RPL15,SATB1,ATXN7,FOXRED1,SH3BP2,DHX30,KDM4D,GLT8D1,ZNF621,CLASP2,NEK4,ANKRD28,TBCEL,TPCN2,FRYL,SIK3,MTMR14,NR2C2,PRDM10" Coexpression 17332353-Table2 Human Breast_Huang07_161genes GeneSigDB 1.57E-03 1.00E+00 1.80E-02 1.79E-01 26 127 "PLEKHH1,KIAA1324,EPB41L5,CA12,CALM1,CAST,SCARB1,EPS15L1,ABCG1,SOCS5,GREB1,MYEF2,EGFR,UBE2E3,ZNF559,SPIN1,ICA1,IFI16,INPP1,MAPT,SH3KBP1,ARX,ST5,CBX5,TRPS1,SLC38A1" Coexpression 16818645-SuppTable2 Human Uterine_Lucerna06_67genes GeneSigDB 1.59E-03 1.00E+00 1.83E-02 1.81E-01 14 53 "TNRC6C,DOCK11,LONRF2,CRLF1,DNM1,FGFR3,BAIAP2,GFRA2,HBA1,MYLK2,PIK3AP1,SNAP25,ARC,ZIC2" Coexpression M2940 Genes down-regulated in CD8 T cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v6.0) 1.59E-03 1.00E+00 1.83E-02 1.81E-01 33 174 "ACTN1,ADCY6,CARNS1,TNRC6C,NUMB,ABCG1,IPCEF1,SIPA1L1,PLEKHA1,PAN3,CHST15,RAPGEF6,NEU3,SESN1,TDRKH,ELOVL5,IL6ST,SLC11A2,PDE4B,PIK3C2A,EXOSC10,EML5,SLC25A36,ST6GAL1,DZIP1,TET1,POGZ,ZEB1,SSBP2,TTC3,MICU3,PHTF2,KLHDC1" Coexpression 18024791-Table2 Human Lymphoma_OrtegaPaino08_46genes GeneSigDB 1.62E-03 1.00E+00 1.86E-02 1.84E-01 12 42 "ACTN1,SLC16A4,HOMER3,CNN3,CST3,DBN1,OPTN,CHL1,ENPP2,PRKCB,TIAM1,TPM2" Coexpression 20194811-Figure1c Human Lung_not_cancer_Lockstone10_51genes GeneSigDB 1.62E-03 1.00E+00 1.86E-02 1.84E-01 12 42 "ZNF608,CDC42BPA,MPDZ,FRY,EFCAB2,ADGRA3,KLHL23,PRKAB2,HKR1,ADHFE1,SYNE1,STXBP4" Coexpression 20179214-Table2 Human Brain_DePreter10_42genes GeneSigDB 1.62E-03 1.00E+00 1.86E-02 1.84E-01 12 42 "ARHGEF7,FYN,INPP1,MAPT,MYCN,NRCAM,PMP22,PRKACB,PTN,PTPRN2,EPN2,CAMTA2" Coexpression M5329 Genes positively correlated with amplifications of MYCL1 [GeneID=4610] in SCLC (small cell lung cancer) cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.64E-03 1.00E+00 1.87E-02 1.86E-01 6 13 "CNRIP1,HPCAL4,KCND2,NELL2,NDRG4,FAM13C" Coexpression M465 Genes down-regulated in splenocytes from OT-1 TCR transgenic mice: control versus IL-12 treatment. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-03 1.00E+00 1.88E-02 1.86E-01 27 134 "APAF1,USP37,SHROOM2,CBFA2T2,HINFP,PDE4DIP,TBC1D5,CPEB2,DNM1L,GOLGA7,POLK,FOLR2,POMT1,GPR34,PRDM5,NFYA,SCN7A,ZHX3,UHRF1BP1L,SAMSN1,LARP4,NEK4,FBXW11,TBL1X,TRO,USP1,HNRNPA3" Coexpression M2185 "Genes up-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.65E-03 1.00E+00 1.88E-02 1.86E-01 27 134 "TMCC3,SORCS2,APBB2,BMP7,ARHGEF25,LRIG1,SIPA1L1,MRVI1,TAOK3,CSDC2,SPIN1,PRUNE2,GSN,CAMK2N2,MATN2,MEIS2,NFIX,PLTP,SEPT4,PKIA,ENOX1,ZHX3,ZNF423,MCF2L,TCF4,WIPF1,STOX2" Coexpression M7720 Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-03 1.00E+00 1.88E-02 1.86E-01 27 134 "TAOK1,MAP4K4,AKAP7,CSNK1G3,MTX3,IRAK4,ZBED3,TNRC6A,MATN2,NFE2L2,PDPK1,PNMA3,PTK2,CEP97,BEND5,RBBP6,FAM161B,R3HDM2,BTBD7,ATF7IP,MAPKBP1,SP4,KDM4C,ARHGAP26,KLHL7,TCEA1,NT5M" Coexpression 20220088-SuppTable3 Human Immune_Allen10_81genes GeneSigDB 1.67E-03 1.00E+00 1.90E-02 1.88E-01 15 59 "MTUS1,KIAA1324,CDH2,CHGB,HEYL,GNG4,TOX2,SMAD1,NTRK3,KSR2,ST8SIA1,PEG10,HEY1,DCBLD1,FZD3" Coexpression M4991 'PAX-FKHR signature': genes up-regulated by PAX3- or PAX7-FOXO1 [GeneID=5081;5077;2308] fusion in primary alveolar rhabdomyosarcoma(ARMS) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.67E-03 1.00E+00 1.90E-02 1.88E-01 15 59 "ALK,ANK2,TMEFF1,ARRB1,MARCH3,JAKMIP2,RASL10A,INPP1,KCNN3,MN1,MYCN,NRCAM,MORC4,MEG3,SGK1" Coexpression M12490 Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.67E-03 1.00E+00 1.90E-02 1.88E-01 114 782 "RALGAPA1,ABR,SPARCL1,ALK,BIN1,OGT,CDC42BPA,ANK2,MAP4K3,ARRB1,RGS20,ZBTB10,NUMB,EIF4G3,ATP2A2,ADAM23,LDLRAD4,CALM1,CBR1,CDC25B,NPIPA1,SRSF11,CDC42BPB,C2CD2,CREM,NCOR1,PDE4DIP,GREB1,DOCK4,DCAF8,HDAC4,DAPK1,PITPNC1,ZC3H11A,SACS,CASP8AP2,RCAN1,ANKRD46,FRY,PHF20L1,EGR3,PLXNC1,VPS13B,MFSD10,SH3YL1,TBC1D16,OLFM1,FGF13,BAIAP2,TMEM164,FHL1,SYNCRIP,FLNC,FAM49B,ATP6V1H,TCERG1,COPS8,ADGRA3,SYNPO,MSL1,IFI16,KIT,MAN2A2,MARK3,MEIS2,PTOV1,MYO6,NF1,NME4,CNOT4,SLC11A2,NUCB2,PDE4A,PFKFB3,PIK3C2A,RETREG1,PKM,FAM216A,PLTP,WBP1L,PTK2,PEX2,QDPR,RAP1GDS1,OXR1,RDX,REV3L,RPS6KA2,CLIP1,TRAPPC13,SGK1,SMARCA4,FNBP1,ZHX3,SPTAN1,CDK19,PRRC2C,SYNE2,ASTN2,MTCL1,ATMIN,TCEA1,TCF12,DOCK9,NACC2,TRIO,TTC3,UBE3A,VLDLR,WIPF1,REEP1,MAP3K12,JMJD1C,NETO2" Coexpression 16849537-SuppTable4 Human StemCell_Davicioni06_106genes GeneSigDB 1.71E-03 1.00E+00 1.94E-02 1.93E-01 18 77 "ALK,ANK2,TMEFF1,ARRB1,JAKMIP2,EYA1,GATM,MSTN,FAM69A,ITPKB,MN1,MYCN,NRCAM,EPB41L4B,MORC4,MEG3,SOX11,TCF4" Coexpression M2438 Genes whose DNA methylation differed between primary ALL cells (acute lymphoblastic leukemia) and normal peripheral blood samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.71E-03 1.00E+00 1.94E-02 1.93E-01 18 77 "CLOCK,SUSD5,SMC2,KHDRBS3,NFU1,AGFG1,HSF2,SFXN5,LRP1B,ZNF827,MRAP2,HSPA4L,MCF2L2,RUNDC3B,RPRM,FSTL5,SMARCAD1,FBXO36" Coexpression M422 Genes down-regulated in dendritic cells: immature versus mature inhibitory treated by prostaglandin E2 [PubChem=5280360]. MSigDB C7: Immunologic Signatures (v6.0) 1.72E-03 1.00E+00 1.94E-02 1.93E-01 28 141 "HFM1,UPRT,ARHGDIG,ASGR1,CARMIL3,RGS9,BLM,CTH,MYADM,KCTD8,TMCC2,DMPK,EGFR,RAB9B,NCALD,AMOTL2,TPPP3,HIGD1B,C1QL4,ICA1,KIT,PACRG,NEK1,GNG2,MYO16,TSNAXIP1,SYNE2,VWCE" Coexpression 20096135-Table2 Human Liver_Utispan10_75genes GeneSigDB 1.73E-03 1.00E+00 1.95E-02 1.94E-01 17 71 "NME5,ADGRF5,NRP2,DCLK1,SPOCK3,EBF1,SEMA3D,PCOLCE2,PCDH17,ITGA7,KIT,MATN2,ENPP2,RELN,PTPRO,TNFRSF19,PKNOX2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.26E-11 4.50E-07 1.21E-09 1.10E-08 52 196 "TRMT9B,CADPS,GPC2,THSD7A,PTBP2,VXN,PRC1,CBFA2T2,SEPT7,CDC25B,FOXN3,IGDCC3,EPB41,ADGRV1,NRN1,CLVS1,TUBB3,SPSB4,AMOTL2,DLL3,SRRM4,IGFBPL1,INSM1,STMN1,AFDN,MSI1,TAGLN3,NOVA1,NPTX2,PCDH8,SEMA5B,GPSM2,SCHIP1,ZMAT4,RGS4,KLHDC8A,FBXW7,RPS20,MEG3,HES6,TNFRSF19,ANKRD6,SOX11,SULF2,SEPT3,RHBDL3,TCF12,TSPAN11,MKRN3,ZNF195,TUBA1A,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.48E-11 4.60E-07 1.24E-09 1.12E-08 44 151 "FAM135A,VAT1L,CADPS,RNF182,ADAM23,LDLRAD4,CACNA1B,THSD7A,PTBP2,RUNX1T1,CDH2,DCLK1,RCBTB2,CNR1,COL9A1,CRYM,JAKMIP2,EBF1,EDNRA,ETV1,EYA1,FGF13,UBE2E3,MEX3B,NBEA,SRRM4,GRIA2,RASSF8,BACH2,NEGR1,MAP2,MYH3,NEFM,GPR85,GNG2,NALCN,PCDH18,TRHDE,ZMAT4,ANKRD6,ADGRL3,PCDHB10,PCDHB3,RPRM" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 9.51E-11 4.62E-07 1.24E-09 1.12E-08 26 62 "PCDH10,ANK2,CADPS,FAM171B,RIMS2,JAKMIP2,ZNF804A,SPOCK3,DENND4A,EYA1,TUBB3,GABRB3,SRRM4,GNAO1,GRIA2,SYTL4,NCAM2,NEFM,NOVA1,PCDH9,STK32A,EML5,SNAP25,SYT1,CUX2,FSTL5" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k3 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.99E-11 4.85E-07 1.30E-09 1.18E-08 61 250 "RNF150,SRPX,ARHGAP20,SYT13,DPP10,ANK2,TNRC6C,ADGRB2,ADGRB3,CACNA2D1,RUNX1T1,DCLK1,CNTN1,COL9A1,GRIN3A,DNM1,EBF1,EDIL3,EGFR,PLXNC1,NCALD,MRVI1,MEGF10,GABRB3,FREM1,PTPRT,IRAK3,UBE2QL1,NEGR1,LSAMP,AFF1,MMP16,MN1,NTRK2,CLDN11,PDE1C,SDK2,PTX3,RGS4,ZFHX4,LGI2,KIRREL1,MEG3,CSRNP3,LRFN5,ZFP2,TRA2B,ST8SIA1,SLC14A1,CXXC4,ZC3H13,CLSTN2,NEK4,ADGRL3,CUX2,FAM189A1,PCDHB3,ASXL3,RGMB,FLRT2,NETO1" Coexpression Atlas PCBC_SC_blastocyst_1000 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.07E-10 5.18E-07 1.38E-09 1.25E-08 167 996 "KCNH8,SYN3,TMEM132B,ADCY5,GALNT13,ADD2,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DPP10,VAT1L,PPP4R4,RASL11B,ATP1A3,KIF1A,CARMIL3,ADGRB1,LDHD,CBS,CLDN10,CCK,SYNGR3,L3MBTL4,DLGAP1,CACNA2D2,FAM19A5,IGLON5,CNTN1,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,IGDCC3,GDA,LRRC3B,RIMS4,CNTNAP2,FAM169A,SEC14L5,KATNAL2,RIPOR2,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,DPP6,SLC25A18,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SYT3,CSPG5,ABLIM2,MEGF11,MEGF10,HRASLS5,GABRA3,GABRB3,SRRM4,GFRA2,TTBK1,GNAL,GNG4,LPAR4,STMN2,SOX21,LINGO1,PSIP1,RNFT2,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,C2orf72,ZIC5,KCND2,KCNN1,KIF5A,CAMK2N2,MATK,CHST6,SCAMP5,FXYD7,NELL2,NPTX1,NTRK3,NLGN3,SEMA5B,JAKMIP1,NECAB2,EPB41L4B,PPP2R2B,PPP2R2C,NKAIN4,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,KHDRBS2,ZMAT4,RET,PRIMA1,RORB,MRAP2,SGSM1,HUNK,STX1B,SALL1,TMEM200C,SH3GL3,PPM1E,CNKSR2,PREX2,TET1,SNRPN,SOX3,SOX15,NMNAT2,SSTR2,SOX21-AS1,SEPT3,RHBDL3,NUDT10,SYN1,ARC,SYN2,SYP,SYT1,COBL,KLHL4,FAM189A1,SLC19A3,RNF175,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,DPYSL5,PROCA1,SLC30A3,CADM2,GAL3ST3,SLC17A7,NETO1,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.22E-10 5.90E-07 1.57E-09 1.42E-08 143 817 "CCDC85A,ADORA2A,ADRB2,ZNF608,HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,BIN1,SUGT1P4-STRA6LP-CCDC180,APBB2,UPRT,SHROOM2,ARRB1,DOCK11,ADAM15,BACH1,NRP2,ARHGEF7,CA8,LDB2,CD38,ARHGEF2,CHN1,MS4A7,TAOK2,ABCG2,TMEM184B,MAP4K4,LY86,ARHGEF6,ZNF521,CNRIP1,CREM,CRMP1,HAPLN1,CSF1R,CYBB,DOCK4,RASSF2,GIT2,DBN1,ARMCX4,PITPNC1,JAKMIP2,ELMO1,FAM107B,EBF1,EDIL3,EDN1,EDNRB,PLEKHA1,CALCRL,RASGRP2,STX2,DENND4A,CEP85L,CORO2B,DLC1,IQCG,FLT1,UFM1,PDLIM5,TRIM16,ST6GALNAC3,FYB1,FYN,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,LPAR4,STMN2,MAP4K5,NCKAP1L,ZDHHC15,AGFG1,ICA1,IGF1,KIT,LIFR,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,MYO6,PALM,PDE4B,PDE4D,GNG2,PFKFB3,DRAM2,RASGEF1B,SNRK,PTK2,PTPRB,RIPOR1,TMEM255A,C1orf54,RDX,SEMA6D,RASA3,SGK1,FAM102A,SLA,PREX2,BTBD3,CPEB4,LIMCH1,FNBP1,UNC5B,PEG10,SAMSN1,THSD1,RGL1,STXBP1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,DOCK9,TEK,ZFPM2,C18orf54,HEY1,TLR4,NPL,DCBLD1,FLRT2,WIPF1,ZNF711,ADAMTS9,NAV3,FAM13C,DOCK8,JMJD1C,NHSL1,RNF146" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.22E-10 5.94E-07 1.58E-09 1.43E-08 86 412 "KLHL13,OSBPL6,ALCAM,ARHGAP20,PCDH10,FAM135A,CADPS,ADGRB2,IL33,CACNA2D1,CALB1,LDB2,CD86,CFL2,NRXN3,LY86,CNTN1,COL9A1,CNRIP1,AKAP12,CRYM,VCAN,PLXNC1,CALCRL,EPB41L2,RASGRP2,EPHB1,NCALD,MRVI1,HSPA12B,SMC2,TVP23A,GALC,FREM1,RAB40B,GRB10,GUCY1A1,HAS2,UBE2QL1,ZHX1,NEGR1,SCIN,LAMA2,MATN2,MEIS1,MMP16,MSR1,NDP,CNOT4,CLDN11,PCDH8,PCDH9,PDE3A,GPR85,PIK3C2A,TRHDE,MBOAT7,KANSL1,NKAIN4,PTPRO,PTX3,REV3L,LGI2,LRFN5,SCN7A,ST8SIA1,CXXC4,SNCA,MYCBP2,SAMSN1,STX1A,PDLIM2,MGRN1,CUX2,ENHO,ERCC6L2,RGMB,SYNPO2,SSBP2,FLRT2,VLDLR,PROCA1,SPIRE1,NAV3,MSRB3,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.25E-10 6.09E-07 1.61E-09 1.46E-08 29 76 "SCAPER,CACNA1B,RUNX1T1,KIAA0408,BRINP1,EDIL3,PCDH17,GNAO1,PCLO,CNTRL,STMN2,GRIA2,MEIS2,NNAT,PCDH9,PRKCB,PTPRN2,REV3L,ZFHX4,MEG3,RTN1,SEMA6D,SLC8A1,MYCBP2,ERC1,SYT1,CELF4,REEP1,TMEM178A" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.32E-10 6.41E-07 1.69E-09 1.53E-08 34 100 "PCDH19,HAP1,SRSF11,LHX2,NRXN3,IGDCC3,CNTNAP2,RIMS2,SCRN1,JAKMIP2,EMX2,ADGRV1,SRRM4,MAP7D2,STMN2,RNF165,SOX21,USP51,SHC3,MYT1,NRCAM,PAX6,SEMA5B,ELOVL2,EML5,STRC,SALL1,HSPA4L,KIF21A,ARX,SYN1,NR2E1,WNT7A,ZIC1" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0 gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0 Gudmap RNAseq 1.36E-10 6.62E-07 1.74E-09 1.58E-08 203 1278 "SYN3,ABHD6,AS3MT,NCKAP5,ADCY6,AXIN2,PLEKHH1,KIAA1211,PCDH19,NME5,KIAA1324,AK2,CEP126,ZNF687,AMPH,AMT,FGD2,EPB41L5,CPNE5,LGR5,CDC14B,ARHGDIG,ATP1A1,BCL7A,PROM1,BMP7,BMPR1B,WASF1,CA12,DDR1,HAP1,MTMR7,CBFA2T2,LRBA,LONRF2,LRWD1,CBARP,CHN2,B4GALT6,PPT2,MYL6B,QKI,CNR1,ZNF385A,SH2B1,IPCEF1,PLXNA4,FAM169A,PLCXD3,CTH,GREB1,HDAC9,KATNAL2,DAPK1,SNAP91,SGSM2,CDON,DPP6,DTNA,SEMA3D,APH1A,KCTD3,PLEKHA1,CERCAM,ENO2,ERBB2,SPEG,EYA1,CD320,REEP2,ZSCAN30,SPSB4,EVL,SEMA4D,SYT3,C2orf88,POMT1,HVCN1,GALNT15,GALC,SYT17,NFU1,GFER,GGT7,PPARGC1A,RUNDC3A,TOX3,KIAA1958,KDM2B,POLL,LNX1,PLPP7,GRIK5,RNF165,SLC2A6,FAM222A,MUM1,PADI2,FRMD5,ACOT7,IBA57,SLC6A17,SLC35G1,KCNJ16,KCNK3,GATD1,KHK,STMN1,SYTL4,LYPLAL1,MATK,AQP11,ADAM11,SAMD5,TAGLN3,MYCN,LYRM9,KSR2,ZNF827,CDK18,PDE1C,PDE4A,PDE1B,FAM98B,PFKFB4,ZDHHC8,SEMA5B,RETREG1,PKM,KCTD15,SLC25A23,PLXNB1,POLR2F,FSD1,PPP1R1A,NKAIN4,GDPD1,LAMA1,SPDL1,PTPN13,EML5,PTPRG,NKAIN1,TMEM231,FAM184A,ROGDI,ZMAT4,FIGN,KCTD17,C12orf49,ARMC5,PCMTD2,KIAA0895L,RPS6KA2,RTN1,SCN2B,SCN8A,HES6,TNFRSF19,ZNF821,SH3BP2,KIF16B,SHMT2,FHOD3,ST6GAL1,WDR37,PEX26,SLC8A1,ABTB1,INAVA,SOX11,STAC2,KANK1,SYP,TBCEL,WSCD1,CUX2,CYB561A3,TMEM9,TK2,BEX4,LRRC24,DCBLD1,HSPBP1,UBE2H,UCHL1,MTCH1,CCDC136,VLDLR,KLC2,ATP6V0E2,SPHK2,POLR3H,SH3GLB2,MEIS3,INTS3,ZXDA,SLC38A1,CIAPIN1,SEMA3B,WNK2,FZD3,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.40E-10 6.80E-07 1.79E-09 1.62E-08 83 393 "EMILIN3,ADRB2,FAM135A,CADPS,MYOM1,CA8,CACNA2D1,CFL2,CNTN1,COL9A1,CNRIP1,VCAN,PLCXD3,EDNRB,EIF5,RGS17,DCTN4,EPB41L2,NCALD,ETV1,RASL12,MRVI1,DLC1,SUCO,SYNCRIP,SMC2,PDLIM5,MEGF10,GALC,RAPGEF6,GFRA2,PCDH17,FERMT2,PRUNE2,HAS2,ZHX1,NEGR1,RBPJ,LAMA2,LIMS1,HECTD2,NCOA7,MBNL1,CHIC1,MEIS1,MKLN1,MMP16,NPTX2,NTRK2,CLDN11,CNTN3,PCDH9,ENPP2,NALCN,PIK3C2A,SCHIP1,KANSL1,DIRAS2,PTX3,REV3L,LGI2,KCNIP3,RYR3,SH3BGR,SH3GL3,FAM126B,ZHX3,VPS13A,SYT1,AGTPBP1,SYNE1,ZFPM2,ERCC6L2,R3HDM1,RASD2,TPM2,RGMB,SYNPO2,TRPS1,SSBP2,VLDLR,RBFOX3,MSRB3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 1.42E-10 6.88E-07 1.80E-09 1.63E-08 97 488 "EMILIN3,NDRG2,CCDC85A,SEMA6A,ALCAM,ARHGAP20,PCDH10,LTBP4,GPRASP2,APLP1,VAT1L,LGR5,CDK10,ADGRB2,ADGRB3,CACNA1G,LDLRAD4,CACNA2D1,CBLN1,KCNAB3,CDO1,CRLF1,PCYT1B,COX4I1,ANKRD44,CSF1R,B3GAT3,RUSC2,EBF1,EDNRB,SEMA3D,EGFR,ELN,EMX2,ENO2,LRRC17,ADGRV1,TUBB3,FCGRT,FGF11,TRIM16,NSG1,FYB1,TMEM8B,PCDH17,PPARGC1A,NTNG2,ZNF276,MAP7D2,TDRKH,GSN,RASSF8,TOX2,HLF,SYNPO,SRSF12,COMMD5,THYN1,NCAM2,NEFM,NELL2,NFIX,CNTN3,PAX6,PCDH9,PDE4D,SEMA5B,ZFYVE21,PLCL1,PLTP,TRHDE,FSD1,POU6F1,IRX1,PRODH,ACSS3,ZMAT4,RTN1,FERMT1,SMARCD3,ADGRL3,WSCD1,PHF24,FAM189A1,KCNE5,TST,UCHL1,PLPPR2,TSPAN11,ZIC1,ZIC2,TMEM237,DPYSL5,CADM2,WNK2,KLHDC1,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.52E-10 7.39E-07 1.93E-09 1.75E-08 114 608 "EMILIN3,CCDC85A,RTL9,SEMA6A,KCNAB2,CDK10,IGDCC4,SPTBN4,RASL11B,BMPR1B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,LRBA,CDO1,CRLF1,CLTB,COL9A3,ABI3BP,IGDCC3,ANKRD44,CLIP3,SNCAIP,BOC,ARHGAP24,RHOBTB1,GRIN3A,DNM1,MBNL2,EPB41,LRRC17,DENND4A,HSPA12B,FCGRT,FDFT1,SCARA3,FOXF2,AFF2,NBEA,TRIM16,NSG1,STAU2,TVP23A,ZMAT1,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,BACH2,SYNPO,INPP1,JAK2,CREG2,LAMA2,LAMP2,SMAD9,MAN2A2,TM6SF1,MEIS2,SRSF12,MSR1,N6AMT1,FXYD7,NFIX,NPY,ZNF827,CNTN3,PDE3A,PDE4D,PFKFB2,SDK2,EPB41L4B,CCDC144B,DIRAS2,CNTLN,IQSEC3,FAT4,BEND5,MORC4,ZFHX4,MRAP2,BAALC,SH3GL3,CNKSR2,DZIP1,SLC8A1,SMARCC2,RCOR3,DOP1A,CDK19,DIP2A,ARHGEF9,PLCB1,TACR1,ANKRD12,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPS1,TSPAN11,WIPF1,ZNF32,NAV3,KLHDC1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.60E-10 7.77E-07 2.02E-09 1.83E-08 38 121 "ATP2B2,CARMIL3,HAP1,SRSF11,NRXN3,SLC35F1,CNTNAP2,SCRN1,DLX1,DTNA,EDNRB,ADGRV1,TUBB3,GAD1,SRRM4,ACSS1,STMN2,RNF165,TOX2,FRMD5,IGFBPL1,MAP2,MBP,SHC3,MYT1,NELL2,MAPK10,GDPD1,RTN1,HSPA4L,MAST1,SNAP25,SYP,MGAT5B,ZIC1,CELF4,DPYSL5,FZD3" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.62E-10 7.85E-07 2.04E-09 1.85E-08 135 761 "USP31,ADRB2,HECW2,ADGRF5,SHROOM2,ARRB1,ARRB2,NRP2,GPR146,ARHGEF7,LDLRAD4,CA8,LDB2,CD86,SCARB1,CD38,CHN2,MS4A7,QKI,MAP4K4,LY86,ARHGEF6,RBM39,CRMP1,HAPLN1,CSF1R,PPP1R16B,CYBB,KIF26A,RASSF2,ELMO1,SACS,FAM107B,SEZ6L2,EDNRB,EBI3,CALCRL,EPHB1,SLC43A2,IGSF6,TLR7,SIRPB1,F8,CORO2B,DLC1,FCGR1A,FLT1,SMC2,TRIM16,FYB1,ERAP1,GATM,PCDH17,GGTA1P,LYVE1,GPR12,LPAR4,PRDM5,NCKAP1L,ICA1,IRF8,IFI16,IGF1,KIT,LIFR,LMO2,SMAD1,PIK3AP1,MAP4,TM6SF1,MEF2C,MEIS2,KITLG,MSR1,MYO7A,P2RY13,NCF2,NRCAM,P2RX7,PDE4B,GNG2,SEMA5B,SCHIP1,KANSL1,PRKCB,RELN,SNRK,PTPRB,PTPRE,PTPRO,PTX3,TMEM255A,SH3TC2,RGS3,ATP8B4,MAPK12,SEMA6D,RASA3,SGK1,FAM102A,ST8SIA1,SLA,PREX2,BTBD3,SLC11A1,LIMCH1,ARHGAP26,CLASP2,SAMSN1,THSD1,NEK4,CEP68,RGL1,SLC37A2,TAL1,KLHL4,DOCK9,ARHGAP9,TEK,TLR4,ERCC6L2,NPL,TRIO,VAV1,WIPF1,AMZ1,GDPD5,ADAMTS9,PLD4,RGS7BP,FAM13C,DOCK8,MSRB3,SOCS4,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.65E-10 8.01E-07 2.08E-09 1.88E-08 41 137 "PCDH10,DPP10,TNRC6C,ADAM23,CACNA1B,RUNX1T1,FAM171B,ANKRD44,SNCAIP,SIPA1L1,PYGO1,JAKMIP2,GRIN3A,EGFR,ETV1,EYA1,TMEM132C,FOXF2,GFRA2,GRIA2,IFI16,NDP,NEFM,CLDN11,GPR85,TRHDE,FAT4,ZFHX4,ARMH4,SALL1,TNFRSF19,ARHGEF9,MTCL1,ADGRL3,CUX2,FAM189A1,PCDHB7,TIAM1,TRPS1,RPRM,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.92E-10 9.31E-07 2.41E-09 2.18E-08 88 429 "HECW2,PCDH10,SYT13,LCORL,VAT1L,CADPS,INSYN2B,RNF182,ADAM23,DST,RUNX1T1,CBLN1,DCLK1,CDO1,CLGN,CRLF1,CNR1,ZNF521,ANKRD44,NCOR1,CRYM,ERC2,PYGO1,SCRN1,PITPNC1,JAKMIP2,TIAM2,SPOCK3,DLX1,EDNRA,EGFR,TENM1,EYA1,TMEM132C,SCML2,FOXF2,NBEA,MEGF10,PPARGC1A,TOX3,GNG4,ADGRA3,LPAR4,GRIA2,IFI16,LSAMP,MYH3,NDP,PCDH8,PDE4D,ENPP2,GPR85,NLGN3,TRHDE,LRP12,ING3,EPB41L4B,PTPRE,TMEM255A,GAL3ST4,FIGN,ZFHX4,C12orf49,ROBO1,SALL1,SATB1,CSRNP3,TNFRSF19,ANKRD6,SLC14A1,LIMCH1,SOX11,TROVE2,TTBK2,KLHL7,CAMTA1,ADGRL3,TCF4,PCDHB15,PCDHB10,PCDHB3,SYNPO2,UGT8,WIPF1,PCDH20,KCNAB1,FAM13C,SOCS4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.96E-10 9.49E-07 2.44E-09 2.21E-08 39 127 "PLEKHH1,PTCHD1,HAP1,CLCN3,CRMP1,SLITRK5,RIMS2,DTNA,EPHB1,RRAGB,EXTL2,ADGRV1,REEP2,SPSB4,DLL3,GABRB3,SRRM4,TOX3,STMN2,RNF165,TOX2,FRMD5,DDX19B,CELF5,ZIC5,MSI1,NRCAM,NLGN3,MAPK10,RTN1,HSPA4L,SYP,MCF2L,WSCD1,MGAT5B,ZIC1,DPYSL5,FZD3,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.96E-10 9.49E-07 2.44E-09 2.21E-08 39 127 "TMCC3,AP2A2,KLHL13,PCDH10,SYT13,ZBTB10,SCAPER,RUNX1T1,NRXN3,CRHBP,KIAA0408,SNAP91,RCAN2,FGF13,NSG1,FUT9,AP4B1,STMN2,TOX2,NEGR1,SHISA6,SHISAL1,LSAMP,TAGLN3,GPR173,PDZRN4,POU6F1,MEG3,RTN1,SEMA6D,SNCA,PEG10,LMO3,CLASP2,DOK6,UCHL1,CELF4,REEP1,NETO2" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_500 DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.97E-10 9.58E-07 2.46E-09 2.23E-08 85 409 "ADD1,PWWP2A,INTS2,TAOK1,LCORL,PKP4,INSYN2B,RNF182,DOCK11,BACH1,CALB1,RUNX1T1,SRSF11,SLIT2,QKI,CNR1,COL4A5,RBM39,FAM169A,PUM1,DOCK4,TCAF1,AIF1L,ZC3H11A,GSDME,DRP2,EDNRA,PLXNC1,EIF4G1,EMX2,EPB41L2,SCML2,MEX3B,SMC2,APOPT1,TUBGCP4,SRCAP,LPAR4,GPR37,INSM1,KCND2,CHIC1,MEIS1,MEIS2,KITLG,MMP16,MSI1,NEFM,CNOT4,SERPINI1,KANSL1,TMEM255A,C1orf54,PBRM1,ZFHX4,TMLHE,ROBO2,PCMTD2,MEG3,CSRNP3,FNIP1,TRA2B,ARX,CHD9,SYBU,SLC12A2,CPEB4,ZKSCAN3,ZC3H13,RBM26,TROVE2,LARP4,SYNE2,KLHL4,CBX5,ACTR6,ASXL3,NR2C2,SSBP2,FLRT2,PCDH20,ZNF711,EMX2OS,ADAMTS9,GAN" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 2.05E-10 9.97E-07 2.55E-09 2.31E-08 103 533 "ABCF1,KIAA1324,TAOK1,CEP126,PARG,EPB41L5,USP37,DOCK11,ZNF599,PROM1,KSR1,PTBP2,CDH2,CFL2,PLAA,CNTFR,AHCTF1,IGDCC3,FAM169A,KATNAL2,JAKMIP2,DDX46,POM121,CASP8AP2,PHF20L1,PLXNC1,EIF4G2,EIF5,PAN3,EPB41,CEP85L,ACSL4,FGF12,FHL1,SMC2,FAM49B,ATP2C1,FUT9,MPP6,KIAA1841,BRD8,TCERG1,DBF4,ZNF638,MAP7D2,FERMT2,PCLO,CIT,SOX21,PSIP1,USP51,LRRTM1,KIT,KTN1,TM6SF1,MIA2,NOVA1,NTRK2,OPA1,PAX6,FAM98B,SEMA5B,SLC25A23,POLG,VPS13C,ELOVL2,PTK2,SPDL1,EML5,CCDC40,RBBP8,RFX3,SAFB,KIF21A,FHOD3,PREX2,PPP4R3A,INTS9,BDP1,SPTAN1,LMO3,LARP4,NEK4,KANK1,PRRC2C,SYN1,ANKRD28,ZNF106,LRRC8A,PDSS1,TTC3,USP1,RBFOX3,XRCC4,KCNT2,REEP1,EML6,SPIRE1,SMARCAD1,PDSS2,MRPL47,RTN4,FXR1" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_1000 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.25E-10 1.09E-06 2.79E-09 2.53E-08 145 839 "AS3MT,C3orf14,FMNL2,KLHL32,ADRB2,OSBPL8,C1QTNF1,ALCAM,APBB2,EPB41L5,APLP1,UPRT,ARNTL,ARRB1,ASPA,TMEM108,ATP6V0A1,SEC11C,CFLAR,DST,CA12,THSD7A,LRBA,LRRFIP1,CACNA2D2,CLCN3,CLTB,C4orf33,QKI,COL4A5,CLOCK,ANKRD44,AATK,SNCAIP,PDE4DIP,KIAA0040,DOCK4,MYADM,ARHGAP32,ARHGAP24,AIF1L,ELMO1,TSPAN5,HIPK3,TMTC1,FRY,OPTN,EPHB1,CEP85L,TLR7,ACSL4,CORO2B,ST3GAL6,UFM1,PDLIM5,ST6GALNAC3,GALC,IQGAP2,ERAP1,SYT17,GGT5,MALT1,NTNG2,RAB30,AIFM3,FERMT2,GPD2,TDRKH,STON1,TPPP,PARD3B,GSN,AP4S1,RASSF8,UBE2QL1,ZHX1,NXPH3,GABARAPL2,SYNPO,HNMT,IL6R,IL6ST,LAMP2,GPR155,MAPT,AFF1,LYRM9,MYO6,NCF2,NEK1,NELL2,NTRK3,PCSK5,PDE3A,PDE4B,PDE4D,CCSER2,RETREG1,PLCL1,SCHIP1,FA2H,MINDY2,PKIA,PTH1R,PTPRD,PTPRO,RIPOR1,FAM184A,ZDHHC14,FIGN,KIRREL1,ROBO2,ST6GALNAC6,GALNT10,HSPA4L,ST6GAL1,CCDC92,ABLIM3,SLA,FAM81A,CPEB4,LMBRD1,KDM4C,DDN,ITPRID2,NXT2,KANK1,VPS13A,TMEM150C,ASTN2,ANKRD12,SYNE1,TNS2,FRYL,NPL,SGK3,FLRT2,PLEKHH2,TOM1L2,ZBTB38,SPIRE1,SEMA3B,AMN1,MSRB3,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.32E-10 1.13E-06 2.87E-09 2.60E-08 86 417 "USP31,TAOK1,PCDH10,DPP10,APC,ADAM23,NRP2,CACNA1B,CACNA2D1,KALRN,RUNX1T1,CHGB,RAB33A,NRXN3,CNR1,COL9A1,MYRIP,SLC35F1,CRHBP,HAPLN1,VCAN,ERC2,PLCXD3,SCRN1,BRINP1,JAKMIP2,ZNF804A,MFAP3L,GRIN3A,PDCD6IP,HIPK3,EIF4G1,TUBB3,CORO2B,DLC1,FOXF2,CAMKK2,MEGF10,GABRA3,CHL1,IQGAP2,SYT17,GFRA2,PCDH17,BACH2,IFI16,INSM1,KIF2A,MAP4,MAPT,NCAM2,NDP,NEFM,NFIX,NNAT,NTRK2,OPRL1,CLDN11,GPR85,DUSP26,NALCN,PIK3C2A,MBOAT7,KANSL1,MAPK10,PRPH,PTPRO,RET,REV3L,RGS4,ZFHX4,RTN1,ANKRD6,SNAP25,STX1A,DNMBP,ADGRL3,TBL1X,CUX2,ERCC6L2,RGMB,SYNPO2,RPRM,UCHL1,STOX2,MSRB3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.37E-10 1.15E-06 2.92E-09 2.65E-08 83 397 "EMILIN3,USP31,AP2A2,TBC1D14,TAOK1,ALCAM,OGT,APAF1,APC,PHYHD1,BCHE,CACNA2D1,CDH2,SRSF11,PREPL,RBM39,VCAN,DZIP3,TM9SF4,MYEF2,PDCD6IP,TSPAN5,EDNRB,HIPK3,SEMA3D,EIF4G1,CALCRL,DCTN4,ETV1,DLC1,SUCO,FLT1,SMC2,PDLIM5,CAMKK2,CELF1,GABRA3,IQGAP2,PCDH17,GHR,FERMT2,GRB10,RASSF8,ZDHHC15,RBPJ,KIT,LIFR,LIMS1,CHIC1,MEF2C,MEIS2,KITLG,MKLN1,MMP16,SAMD5,PDE3A,PIK3C2A,KLHL11,SETD5,RPE,MEG3,CLIP1,TRA2B,PREX2,CPEB4,ZHX3,PEG10,CLASP2,LARP4,PJA1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,ERCC6L2,RGMB,TRPS1,UBE3A,WRN,CLDND1,STOX2,MSRB3" Coexpression Atlas PCBC_EB_fibroblast_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 2.58E-10 1.25E-06 3.17E-09 2.88E-08 165 992 "AXIN2,AGT,SPARCL1,PPFIA4,GAS7,APOC2,LGR5,KIF1A,BMP7,CACNA1G,MYRF,BAIAP3,CA4,CABP7,CAMK2A,CBLN1,DGKI,NOG,CHGB,CHRNA4,NDST3,SLIT2,LHX2,SULT4A1,IGLON5,CNR1,CNTFR,AKAP6,COL9A1,COL11A2,AKAP5,SLC4A8,GAL3ST1,IGDCC3,SNCAIP,GALNT9,RIMS4,PHACTR3,CNTNAP2,PYGO1,BRINP1,PLPPR4,SNAP91,SPOCK3,CDON,DUSP9,EBF1,EDIL3,SEZ6L2,EDN3,HEYL,SEMA3D,PLXNC1,APC2,ADGRV1,NRN1,TMEM132C,ZMYND10,HPCAL4,FOXF2,CSPG5,NSG1,DLL3,TPPP3,MEGF10,GABRA3,SRRM4,CPLX2,CYP46A1,GFRA2,FREM1,PCDH17,CSDC2,RUNDC3A,TOX3,CCDC184,STMN2,TPPP,GRIA2,C1QL4,GRIN2D,GRM8,GUCY1A1,UBE2QL1,IGFBPL1,CELF5,IRF8,C2orf72,IGF1,NKD1,INSM1,CDH20,KCND2,KCNK3,KCNN1,KIF5A,CLEC18A,MAP6,MAPT,MATN2,LRP1B,TAGLN3,MYT1,FXYD7,NEFM,NELL2,NPY,NTRK2,NTRK3,PAX6,PCDH8,SEMA5B,PLCL1,PNMA3,PDZRN4,MAGEL2,PPP2R2B,NKAIN4,SMIM10L2B,PRPH,RELN,PSD,LAMA1,PTH1R,PTPRD,PTPRN,PTPRO,TMEM145,TMEM255A,RGS4,ROBO2,HUNK,KCNIP1,RTN1,TMEM200C,PPM1E,ST8SIA1,MAST1,DMRTC1,SNAP25,CABCOCO1,FAIM2,MYO16,SOX3,NMNAT2,SPP1,PEG10,CLSTN2,SST,SSTR2,SYT5,ADGRL3,CUX2,ASXL3,RIMBP2,RASD2,WNT7A,ZIC1,KCNT2,CRB2,MKRN3,DPYSL5,GAL3ST3,FAM181A,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.61E-10 1.27E-06 3.20E-09 2.90E-08 29 78 "ABR,FMNL2,RUNX1T1,VCAN,KIAA0408,SCRN1,STX2,OGA,PCDH17,TOX3,PCLO,STMN2,GRIA2,NNAT,REV3L,MEG3,RTN1,CASC3,SOX11,SYT1,AGTPBP1,CLASP1,PUM2,ZFPM2,UBTF,CELF4,REEP1,RTN4,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.64E-10 1.28E-06 3.23E-09 2.93E-08 141 811 "EMILIN3,RNF157,USP31,AP2A2,TBC1D14,TAOK1,ALCAM,AMPD3,OGT,APAF1,APC,PHYHD1,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,RUNX1T1,CDH2,CDO1,SRSF11,SLIT2,AKAP5,PREPL,RBM39,NCOR1,VCAN,DZIP3,APPL1,PYGO1,HDAC9,TM9SF4,MYEF2,MFAP3L,PDCD6IP,EDIL3,TSPAN5,EDNRB,HIPK3,SEMA3D,EIF4G1,CALCRL,DCTN4,ENO2,EPHB1,ETV1,MRVI1,NRN1,SCML2,DLC1,SUCO,FOXF2,FLT1,SMC2,PDLIM5,CAMKK2,CELF1,MEGF10,GABRA3,CHL1,IQGAP2,PCDH17,GHR,LYVE1,RAB40B,FERMT2,GPR37,GRB10,RASSF8,HAS2,ZDHHC15,IFI16,RBPJ,IL6ST,KIT,LIFR,LIMS1,CHIC1,MEF2C,MEIS2,KITLG,MKLN1,MMP16,SAMD5,NFIX,NPTX2,PCDH8,PDE3A,PDE4B,PDE4D,PFKFB3,PIK3C2A,PRKCB,GRAMD1C,PTPRD,FAT4,RGS4,KLHL11,ZFHX4,SETD5,RPE,ARMH4,MEG3,CLIP1,TRA2B,SH3BGR,PREX2,SLC14A1,CPEB4,ZHX3,PEG10,CLASP2,THSD1,LARP4,PLCB1,COBL,MTCL1,PJA1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,HIF3A,ZFPM2,TLR4,ERCC6L2,TPM2,RGMB,SYNPO2,TRPS1,UBE3A,WRN,CLDND1,STOX2,FAM13C,ACTR3B,MSRB3,NETO1,SOCS4,SPATA13" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.65E-10 1.28E-06 3.23E-09 2.93E-08 77 358 "FMNL2,AXIN2,KLHL13,SPARCL1,ALCAM,ARHGAP20,APOC1,LGR5,BCHE,CACNA1G,CALB1,SLIT2,VCAN,PLXNA4,BOC,DOCK4,DAPK1,DNM1,DRP2,EDNRA,EGFR,MRO,PLXNC1,EMX2,LRRC17,NRN1,FLNC,AFF2,NSG1,GATM,GFRA2,FREM1,GUCY1A1,GUCY1B1,TCEAL6,IGF1,NKD1,KCND2,KLHL23,SYTL4,MATN2,MEIS1,KITLG,LAYN,MYO9A,NEXMIF,NPR2,PCDH9,ENPP2,PIK3R1,FXYD1,PCDH18,LAMA1,GDPD2,PTN,TMEM255A,FAT4,RNASEL,ZFHX4,MEG3,SEMA6D,TNFRSF19,SLC4A3,KDM3A,UHRF1BP1L,ST5,ADAMTS17,ADGRL3,TCF12,ZFPM2,ACTR6,DCBLD1,TST,FLRT2,VSNL1,LYPD6,WNK3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 2.77E-10 1.35E-06 3.38E-09 3.06E-08 27 69 "SEMA6A,SYT13,RUNX1T1,SNAP91,CPEB2,SEZ6L2,PLEKHA1,TMEM35A,RCAN2,NSG1,STMN2,PTPRT,CELF5,HS6ST3,BEX5,PCSK1,TMOD2,RTN1,NLGN1,SNAP25,FAM219A,PEG10,SEPT3,SYP,VGF,TCEAL7,CELF4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.28E-10 1.59E-06 3.98E-09 3.60E-08 39 129 "ADCY8,DPP10,CADPS,LDLRAD4,DCLK1,COL9A1,COL9A3,FAM171B,CRYM,RIMS2,BRINP1,JAKMIP2,RAB39B,EBF1,EDIL3,EDN3,EDNRB,EYA1,FGF13,UBE2E3,SRRM4,RAB40B,HAS2,UBE2QL1,NEGR1,AGFG1,INSM1,MYH3,NDP,CLDN11,CNTN3,GPR85,TRHDE,ZMAT4,RPS20,ELOVL4,PCDHB10,PCDHB7,RPRM" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500 FaceBase_RNAseq 3.55E-10 1.73E-06 4.30E-09 3.90E-08 97 496 "AXIN2,PLEKHH1,EPB41L5,TTLL9,NRP2,ZNF599,PROM1,CA4,CA12,HAP1,CBLN1,TBRG4,FAM19A5,CNTFR,IGDCC3,FAM169A,CTH,GREB1,RIMS2,JAKMIP2,CHRDL1,PLXNC1,PLEKHA1,EPHB1,PIPOX,RRAGB,ADGRV1,REEP2,ACSL4,SPSB4,FHL1,NOP56,FUT9,GABRB3,TCERG1,TOX3,MAP7D2,LPAR4,STMN2,RNF165,SOX21,TOX2,FRMD5,USP51,NKD1,ZIC5,CDH20,KIT,IPO5,KTN1,AQP11,MYCN,NNAT,NOVA1,NRCAM,PRTG,FAM98B,SEMA5B,PKM,PLTP,MAGEL2,POLR2F,IRX1,MAPK10,GDPD2,ELOVL2,PTPN13,EML5,CCDC40,FIGN,RPL15,RTN1,SALL1,TNFRSF19,HSPA4L,KIF21A,NUBPL,PKNOX2,SNRPN,NMNAT2,PBLD,NEK4,ANKRD28,MTCL1,WSCD1,TMEM121,BEX4,CA14,HSPBP1,MGAT5B,RBFOX3,ZIC1,ZIC2,KCNT2,DPYSL5,FZD3,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_2500_K3 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 3.85E-10 1.87E-06 4.64E-09 4.21E-08 70 315 "KLHL32,PLEKHH1,PHF12,NUMB,MPDZ,BCL7A,BMPR1B,ARHGEF7,CFAP410,PRC1,KRIT1,C1orf52,CDC25B,ZNF445,SRSF11,CHN2,LHX2,QKI,NCOR2,SIPA1L1,RIMS2,USP6NL,RASSF2,JAKMIP2,TMCC2,DLX1,AASDH,PLXNC1,RRAGB,PRKAG2,ATP6V1H,MSANTD4,FYN,IQGAP2,FAM222A,TOX2,PAXBP1,SETD4,ING3,NKAIN1,GAL3ST4,PBRM1,EXD2,ADAL,RMI1,MAPK12,SARS,ZFP2,CASC3,HSPA4L,KIF21A,FBXO11,FAM81A,SLC12A2,SP4,ZBTB43,STAU1,ZC3H4,SYNE2,ATMIN,CLASP1,FRYL,HEY1,BHLHB9,TP53BP1,ZBTB14,PRDM10,RSPRY1,SNX14,GAN" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000 DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.32E-10 2.10E-06 5.20E-09 4.71E-08 135 772 "TMCC3,ADD1,ADORA1,MTUS1,TAOK1,LCORL,PKP4,LGR5,PLA2G4C,PDE8B,INSYN2B,BACH1,SEC11C,RGS11,SYNJ1,ST3GAL5,ARHGEF7,SCAPER,JAZF1,SGCE,USP2,SRSF11,ABI3BP,MYRIP,RBM39,GDA,CSNK1E,PHACTR3,PLXNA4,GREB1,PUM1,ZC3H11A,GSDME,SNAP91,SLC12A6,DTNB,DNAJB6,E2F5,EDNRA,PLXNC1,EIF4G1,MRNIP,CALCRL,EMX2,EPB41L2,LRRC17,SRRM1,EZH1,NRN1,SCML2,KAT8,FOXO3,SMC2,APOPT1,STAU2,FYN,GATM,GDF9,AIFM3,MAP7D2,TDRKH,LPAR4,GUCY1A1,TOX2,SYNPO,HNMT,SHISA6,KCND2,KIT,SYTL4,CHIC1,KITLG,MMP16,MYO5A,NEXMIF,NFIX,CNOT4,SETD4,PDPK1,ABCB1,SERPINI1,NALCN,PIK3R1,JAKMIP1,PLEC,MAPK10,GDPD1,STK32A,SUSD4,RDX,TMLHE,PCMTD2,MEG3,TRAPPC13,SATB1,PRCD,FNIP1,TNFRSF19,ARX,KIF16B,CPEB3,SYBU,WDR37,EPN2,SLC12A2,SLC14A1,CPEB4,ZC3H13,RBM26,CLSTN2,LARP4,PRRC2C,SYNE2,ANKRD12,CAMTA1,DMXL2,DOCK9,PCDHB9,MTMR14,CBX5,R3HDM1,PARD3,NR2C2,TSC1,SSBP2,UBE3A,UCHL1,TBC1D15,TRIM9,NDRG4,ADAMTS9,FAM47E,FAM13C,DPF3,GAN" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.33E-10 2.10E-06 5.20E-09 4.71E-08 86 422 "EMILIN3,RNF157,ALCAM,FAM135A,APAF1,PHYHD1,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,RUNX1T1,CDH2,SLIT2,AKAP5,ABI3BP,NCOR1,VCAN,APPL1,EDIL3,EPHB1,ETV1,MRVI1,TMEM132C,DLC1,UBE2E3,FOXF2,PDLIM5,ZMAT1,MEGF10,CHL1,GABRB3,PCDH17,GHR,LYVE1,RAB40B,MAP4K5,RASSF8,IFI16,KIT,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,ALDH1L2,NPTX2,PCDH8,PDE4B,GPR85,PCDH18,PRKCB,GRAMD1C,FAT4,RGS4,ZFHX4,SETD5,ARMH4,SCN7A,DZIP1,WDR37,SLC14A1,ZHX3,PEG10,THSD1,ELOVL4,PLCB1,COBL,MTCL1,ADGRL3,TEK,ZFPM2,TLR4,ERCC6L2,RGMB,SYNPO2,TRPS1,UBE3A,WRN,MKRN3,CELF4,FAM13C,ACTR3B,MSRB3,NETO1,SOCS4" Coexpression Atlas JC_iEC_2500_K1 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#1 PCBC 4.61E-10 2.24E-06 5.53E-09 5.01E-08 122 677 "ADRA1D,HECW2,KLHL13,CASKIN1,PCDH19,KIAA1324,SORCS2,MARCH4,PCDH10,BBOX1,AMH,CDC42BPA,INSYN2B,NRP2,ST3GAL5,MYRF,CALB1,THSD7A,CH25H,NOG,NGEF,CPS1,MFAP3L,SACS,GRIN3A,DPP6,MAMLD1,TMTC1,TENM1,CALCRL,CD320,HSPA12B,FAM198B,TUBB3,DLL3,HHIPL1,LNX1,MCHR1,STMN2,BVES,SLC2A6,TOX2,ARHGAP36,MIER3,KCNF1,GIT1,SAMD5,MSR1,NDP,NPY,NRCAM,OXTR,PCDH9,PCSK1,PCSK5,PDE4D,TRHDE,FA2H,MAPK3,MAPK7,PRPH,RELN,SNRK,PTCH1,PTPRB,PTPRE,PTPRG,PTX3,RIPOR1,RASGRF1,RGS4,ROBO2,RPS6KA2,STK32B,SEC14L1,SGK1,ZFP30,ST6GAL1,NLGN1,BTBD3,SLC12A2,CXXC4,OGDHL,SNAP25,SOX11,SPP1,SPTAN1,ITPRID2,THSD1,SST,SSTR1,SULF2,PLCB1,ARC,SYT5,ADGRL3,KLHL4,TCF4,SATB2,ZEB1,TCF12,PCDHGB6,PCDHGB2,SLC35G2,TEK,ZFPM2,ARL10,ASXL3,TLR4,NR2E1,TRIO,TRO,TRPS1,VLDLR,TRIM9,LYPD6,CELF4,EML6,LAMP5,TMEM178A,NETO2,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_500 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.11E-10 2.48E-06 6.11E-09 5.54E-08 88 437 "FMNL2,HECW2,KLHL13,SPARCL1,ARHGAP20,PPP4R4,ZSCAN18,TMEM108,MYRF,CALB1,RUNX1T1,CBLN1,DCLK1,MAGI1,CNTFR,AKAP5,ZNF521,HAPLN1,CLIP3,VCAN,PLXNA4,DOCK4,DAPK1,DNM1,CPEB2,DRP2,EDNRA,PLXNC1,C8orf37,EMX2,MTSS1L,CEP85L,FLNC,FREM1,GHR,GPR37,BVES,GUCY1A1,TCEAL6,SHISA6,KCND2,KLHL23,MAP2,MATN2,MEIS1,KITLG,AFF1,NEFM,NME4,NUCB2,PFKFB3,SERPINI1,ZNF655,PCDH18,PPP2R2B,RASGEF1B,LAMA1,PTN,TMEM255A,RADX,ROBO1,ROBO2,MEG3,HUNK,KCNIP1,RASA3,ST8SIA1,SLC4A3,PKNOX2,KDM3A,UHRF1BP1L,PEG10,ST5,ADGRL3,OBSL1,CCDC173,ZFPM2,ACTR6,ASXL3,BEX4,TRPS1,PLEKHH2,VSNL1,PCDH20,ZNF711,LYPD6,WNK3,DPF3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.12E-10 2.49E-06 6.11E-09 5.54E-08 45 164 "EMILIN3,ADRB2,CADPS,MYOM1,CA8,CACNA2D1,CFL2,CNTN1,COL9A1,VCAN,PLCXD3,EPB41L2,NCALD,MRVI1,SYNCRIP,SMC2,PDLIM5,MEGF10,GFRA2,FERMT2,NEGR1,LIMS1,HECTD2,MEIS1,MKLN1,NPTX2,CLDN11,CNTN3,PCDH9,NALCN,PIK3C2A,KANSL1,PTX3,REV3L,LGI2,RYR3,SH3BGR,ERCC6L2,TPM2,RGMB,SYNPO2,TRPS1,SSBP2,VLDLR,MSRB3" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500 facebase_RNAseq_e8.5_FloorPlate_2500 Gudmap RNAseq 5.15E-10 2.50E-06 6.12E-09 5.55E-08 248 1659 "ABCF1,ACHE,PLEKHH1,UNC5A,KIAA1211,ZNF608,NME5,CEP126,AMPH,PHF12,EPB41L5,APLP1,UPRT,VAT1L,ARHGDIG,ARRB2,CADPS,PTCH2,KIF1A,BARD1,BCHE,BID,PROM1,FUBP1,WASF1,MYRF,CA4,CA12,THSD7A,HAP1,PTBP2,CAMK2A,MTMR7,ARHGEF1,CDH2,ZMYM4,LRRFIP1,CCPG1,TBRG4,CACNA2D2,CBARP,NRXN3,PPT2,CLCN3,FAM189A2,FAM19A5,C4orf33,QKI,CNTFR,IQCK,COL9A1,BAG4,IGDCC3,NECTIN3,ZNF385A,SLC35F1,FAM171B,AKAP12,CRMP1,HAPLN1,CLIP3,LRRC3B,FAM169A,CTH,GREB1,KATNAL2,TMEM170A,RUSC2,DDX46,POM121,CASP8AP2,DPP6,FAM78B,DUSP9,E2F5,SEZ6L2,EDN1,YAF2,PAN3,EMX2,RASGRP2,EPHB1,SRRM1,ERBB4,NCALD,EXTL2,ADGRV1,CD320,REEP2,CEP78,PRMT5,OLFM1,POLR1B,SPSB4,AMOTL2,FHL1,IQCG,FLNC,AFF2,NOP56,SYT3,COQ5,CINP,SMC2,USP21,PRELID3A,FUT9,HIGD1B,MTHFD2,GATM,CSDC2,GGT7,TCERG1,DBF4,GLI2,TOX3,KIAA1958,GNAO1,GPD2,LPAR4,STMN2,RNF165,GSTM5,RABL2A,PSIP1,TOX2,FRMD5,HSF2,SHISAL1,LRRCC1,SLC35G1,KIF2A,IPO5,KTN1,CAMK2N2,LSAMP,MAP2,MAP6,MAPT,MAT2A,AQP11,MEST,PPM1L,MSI1,ADAM22,MYCN,LINC00672,NEFM,CNOT4,NOVA2,NRCAM,CLDN11,PDCD2,TMOD2,FAM98B,OLA1,SNX10,RETREG1,PKM,SLC25A23,PRIMPOL,PMP22,FSD1,PPP1R1A,NKAIN4,PRKCB,MAPK4,MASP1,RELN,LAMA1,GDPD2,PTCH1,ELOVL2,ZIK1,PTPN13,EML5,CASTOR1,NKAIN1,CEP97,CCDC40,FAM184A,PRRT2,ERI2,MORC4,FIGN,RFX3,RGS4,NUDT11,LGI2,SETD5,ROBO1,RPL15,KIAA0895L,HUNK,KCNIP3,SALL1,MAPK12,HSPA4L,KIF21A,FHOD3,CCDC92,ANKRD6,PKNOX2,TET1,PDZD2,SOX11,SPTB,RBM26,PBLD,POGZ,LARP4,NEK4,SEPT3,ARC,ANKRD28,MTCL1,WSCD1,CUX2,SIRT1,C18orf54,ITGB3BP,BEX4,STXBP4,CA14,TST,EIF4ENIF1,USP1,CCDC14,LMF1,XPO1,ZNF23,ZFP41,ZNF184,DPYSL5,SMARCAD1,EMSY,SLC38A1,STOX2,TUBA1A,SEMA3B,WNK3,AMN1,FZD3,SMIM8,PHTF2,AAAS,NETO2,SPATA13" Coexpression Atlas GSM538248_500 "Myeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 5.21E-10 2.53E-06 6.19E-09 5.61E-08 80 383 "PTCHD1,ALCAM,FGD2,CASK,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,CSF2RA,PDE4DIP,USP6NL,CYBB,DOCK4,HDAC9,MYADM,ELMO1,CDON,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,FYB1,MALT1,HPGDS,RAB30,ADAP1,ZNF496,GSN,FRMD5,LRRC25,IL6R,ITGAM,JAK2,KCNJ16,KIT,ADAM11,MEF2C,AFDN,ADAM22,LINC00672,MYO5A,PFKFB3,ABCB1,PLTP,RASGEF1B,PRKCB,PTK2,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,MYCBP2,RGL1,SULF2,ADGRL3,KIAA0930,CYB561A3,SLC44A1,TNS1,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas PCBC_ratio_EB_from-plasmid_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-method_plasmid_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.32E-10 2.58E-06 6.30E-09 5.71E-08 36 115 "ANK2,ATP1A3,CACNA2D1,THSD7A,CBLN1,DCLK1,CRLF1,CNR1,KIAA0408,BRINP1,EBF1,EDNRB,APC2,TUBB3,OLFM1,FGF13,CPLX2,RUNDC3A,C1QL4,UBE2QL1,IGFBPL1,INSM1,KIF5A,MAP2,MAPT,MYT1,NOVA2,PTPRN,RTN1,HES6,SNAP25,NMNAT2,NFASC,SEPT3,RGMB,MGAT5B" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.39E-10 2.62E-06 6.36E-09 5.77E-08 54 217 "AXIN2,PCDH10,SYT13,TNRC6C,CADPS,INSYN2B,RNF182,CH25H,RUNX1T1,CBLN1,DCLK1,CDO1,CRLF1,CNR1,ZNF521,ERC2,SCRN1,TIAM2,DLX1,DYNC1I1,EDNRA,TENM1,EYA1,TMEM132C,FOXF2,SYNCRIP,NBEA,MEGF10,GNG4,GRIA2,IFI16,NDP,CNTN3,ZFHX4,ROBO1,CCDC112,SALL1,CSRNP3,ANKRD6,LIMCH1,SOX11,ADGRL3,TCF4,SATB2,ASXL3,KAT6B,TRPS1,RPRM,UGT8,FLRT2,WNT7A,PCDH20,KCNAB1,FRMD6" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500 dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.78E-10 2.81E-06 6.81E-09 6.18E-08 83 404 "FMNL2,HECW2,KLHL13,ARHGAP20,CDC42BPA,APOC1,LGR5,PPP4R4,IGDCC4,NUMB,DST,ST3GAL5,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,RASGRP1,KLHL5,PLXNC1,TMEM35A,EMX2,MTSS1L,NRN1,AFF2,CAMKK2,GALC,GPR37,PACSIN2,SHISA6,IGF1,KCND2,KLHL23,NCOA7,MATN2,MEIS1,KITLG,AFF1,MYO9A,NELL2,NUCB2,SERPINI1,PIK3C2A,PCDH18,LRRN3,PPP3CC,GDPD1,PTPRG,REV3L,ZFHX4,RPS6KA2,HUNK,SEMA6D,TNFRSF19,STUM,MRAS,RASA3,WDR37,SLC4A3,SNCA,KDM3A,UHRF1BP1L,ST5,ADGRL3,DOCK9,OBSL1,DNAH7,ZFPM2,ACTR6,TRPS1,TST,PCDH20,ELFN1,LYPD6,ADAMTS9,SIGLEC10,WNK3,FRMD6,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE76381_iPSMoleculeCountsPMLog2 6.00E-10 2.91E-06 7.05E-09 6.39E-08 32 95 "SYT13,VAT1L,ARHGEF7,RUNX1T1,LDB2,SEPT7,DCLK1,CHGB,PREPL,NCOR1,ARHGAP32,EARS2,SEZ6L2,NSG1,CCDC184,PCLO,STMN2,CELF5,LSAMP,GNG2,TMOD2,PPP2R2B,PTN,ZFHX4,RTN1,SNAP25,PEG10,SEPT3,TUBB2A,VGF,TRIM9,CELF4" Coexpression Atlas gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1 gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1 Gudmap RNAseq 6.16E-10 2.99E-06 7.22E-09 6.54E-08 145 851 "AS3MT,RNF157,ESYT2,MTUS1,LTBP4,PITPNM2,APBB2,GAS7,ARNTL,MARK4,NUMB,ATP1A1,ATP1B3,RIPK1,CFLAR,ST3GAL5,ARHGEF7,RAB29,LDLRAD4,THSD7A,CH25H,SCARB1,ARHGEF2,KCNAB3,CCPG1,TAOK2,PPT2,TMEM184B,CLOCK,CDC42BPB,C2CD2,CREM,AKAP12,ANKRD44,SOCS5,PLXNA4,PPP1R16B,CYBB,DOCK4,MYADM,PITPNC1,RUSC2,C2CD2L,TMCC2,CPEB2,SLC12A6,RCAN1,ARRDC4,ECM2,SNX29,KLHL5,TMTC1,EGR3,IRAK4,ELN,STX2,NCALD,CEP85L,EZH1,HSPA12B,REEP2,CORO2B,BAIAP2,VTI1B,IQCG,ZMYND15,PDLIM5,CAMKK2,ST6GALNAC3,SARAF,FYN,GALNT15,INPP5K,GATM,GCNT2,PCDH17,GGTA1P,STON1,STMN2,IRAK3,RASSF8,GABARAPL2,ICA1,INPP1,KHK,LIFR,NCOA7,MBNL1,MEIS2,MYO6,MYO7A,IDNK,PCSK5,PDE4A,CCSER2,PKD1,DRAM2,MINDY2,PPP3CA,PPP3CC,MAPK3,SNRK,TMEM104,PTPRG,RIPOR1,RGS3,CYB561D1,PCMTD2,RPS6KA2,LRRK2,PTGR2,SEMA6D,SCP2,SEC14L1,PPM1E,FAM81A,EPN2,ABTB1,LMBRD1,TEX2,ARHGAP26,SPTAN1,IQSEC2,PHLDB1,STXBP1,PLCB1,SYPL1,MCF2L,WSCD1,SYNE1,DOCK9,CYB561A3,TIAM1,TK2,LRRC8A,DCBLD1,TUBB2A,SGK3,UCHL1,MTCH1,NPDC1,AGMO,LYPD6,KLHDC1,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.19E-10 3.01E-06 7.24E-09 6.57E-08 139 806 "C1QTNF3,ARHGAP20,BBOX1,AMPD3,ANK2,VAT1L,APOC2,BCAS1,ARRB1,MYOM1,ADGRB3,GPR146,IL33,CA8,CAST,CH25H,RUNX1T1,RGN,CDC25B,DCLK1,UBE2L6,CHGB,CNTN1,PCYT1B,AKAP6,COL9A1,COL9A3,ABI3BP,MYRIP,CPS1,CRMP1,CRYM,SCRN1,SNAP91,TMCC2,GRIN3A,DUSP9,EBF1,AASS,SRPK3,PCOLCE2,EPB41,PIPOX,EYA1,NRN1,F5,CORO2B,FECH,POLR1B,UBE2E3,FOXO3,SPECC1,PDLIM5,TPPP3,MEGF10,ACSS1,CPLX1,ALDH1L1,GFRA2,LYVE1,RAB40B,GNG4,STMN2,GSN,FAM107A,UBE2QL1,ARHGAP36,NEGR1,AGFG1,IFI16,C2orf72,IGF1,SCIN,INSM1,LMO2,LSS,ASPRV1,PIK3AP1,MAP4,MAPT,MEF2C,MN1,MSR1,MYH3,NEFM,CLDN11,CNTN3,PCDH8,GPR85,PGAM2,JAKMIP1,PSAT1,CEP41,PKIA,MAPK10,DIRAS2,PRPH,MASP1,RELN,PTX3,MORC4,RGS4,ZFHX4,LGI2,ATP8B4,MEG3,RTN1,S100B,SALL1,CSRNP3,SCN7A,SH3BGR,ARX,ABLIM3,SLA,SLC14A1,SLC22A4,SNAP25,SNCA,APOM,ADHFE1,SYN2,SYT1,COBL,TAL1,ARHGAP9,HIF3A,VWCE,SYNPO2,PDIA2,VSNL1,ZIC1,AGMO,TCEAL7,SPIRE1,KCNAB1,RGS7BP,FAM13C,NETO1" Coexpression Atlas GSM605839_500 "Myeloid Cells, DC.8-4-11b-.Sp, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Spleen, avg-1" "Immgen.org, GSE15907" 6.73E-10 3.27E-06 7.86E-09 7.12E-08 84 412 "FMNL2,PTCHD1,ALCAM,FAM135A,AMPD3,FGD2,CASK,ADAM23,ST3GAL5,DDR1,CD86,SCARB1,CHN2,B4GALT6,LY86,ZNF385A,CSF1R,CST3,USP6NL,CYBB,DOCK4,HDAC9,MYADM,CDON,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,FGFR1,GATM,RAB30,ADAP1,ZNF496,GSN,FRMD5,IRF8,LRRC25,IL6R,JAK2,KIT,L1CAM,LIFR,ADAM11,MEF2C,MYO5A,MYO9A,NUCB2,PFKFB3,ABCB1,PLTP,RASGEF1B,PTK2,TMEM231,PID1,C1orf54,ROGDI,RGS12,SNX22,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,RGL1,SULF2,TMEM150C,ADGRL3,TCF4,KIAA0930,CYB561A3,SLC44A1,TNS1,NPL,TRPM2,TRPS1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_500 kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.21E-10 3.50E-06 8.39E-09 7.61E-08 82 399 "ADORA1,LGR5,TMEM108,BCL7A,PROM1,BMP7,BMPR1B,CACNA1G,CA4,CA12,CACNA2D1,LRBA,CHN2,SLIT2,CRYM,SNCAIP,VCAN,KIAA0040,GREB1,SCRN1,GSDME,SV2B,EMX2,HSD17B14,ERBB4,EYA1,ST3GAL6,FGFR1,MAD2L2,SCARA3,SEMA4D,IGSF5,GCNT2,FREM1,TOX3,KDM2B,ADGRA3,TDRKH,FAM107A,KCNJ16,CLEC18A,TM6SF1,MID1,MSI1,MYO6,NME4,NPY,PRTG,ENPP2,KCTD15,PLXNB1,SDK2,SEPT4,MAPK4,LAMA1,PTN,PTPN13,FAM184A,ROBO1,GLDN,SALL1,KIF21A,FERMT1,FHOD3,CNKSR2,PDZD2,SOX11,NUDT10,TMEM150C,TACR1,SATB2,CUX2,TRIM2,PCDHB9,HEY1,TRPS1,CA14,VLDLR,SLC38A1,ADAMTS9,FZD3,SPATA13" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.87E-10 3.82E-06 9.14E-09 8.28E-08 133 764 "USP31,BEND6,HECW2,ADGRF5,FGD2,C6orf89,APBB2,SHROOM2,ARRB1,ARRB2,NRP2,ARHGEF7,LDLRAD4,CA8,LDB2,CD86,SCARB1,CD38,MAP4K4,LY86,ZFP28,CNRIP1,RBM39,CRMP1,HAPLN1,ABCG1,CSF1R,LRRC3B,PPP1R16B,CYBB,KIF26A,RASSF2,PITPNC1,ELMO1,FAM107B,SEZ6L2,EDNRB,HIPK3,EBI3,RASGRP2,EPHB1,IGSF6,TLR7,SIRPB1,F8,CORO2B,DLC1,FCGR1A,FLT1,SMC2,TRIM16,FYB1,GALC,PCDH17,GGTA1P,LYVE1,GPR12,NCKAP1L,HP,ICA1,IRF8,IGF1,KIT,STXBP5,LMO2,PIK3AP1,MAP4,TM6SF1,MEF2C,MEIS2,KITLG,MSR1,MYO7A,NCF2,NFE2L2,OPA1,P2RX7,PDE4B,GNG2,SEMA5B,SCHIP1,KANSL1,RELN,SNRK,PTPRB,RIPOR1,TMEM255A,SH3TC2,RGS3,KCTD17,ATP8B4,MAPK12,SGK1,FAM102A,SHMT2,ST8SIA1,SLA,PREX2,SLC9A5,SLC11A1,LIMCH1,MYCBP2,ARHGAP26,SAMSN1,THSD1,NEK4,RGL1,SLC37A2,TAL1,KLHL4,WSCD1,TNS2,ARHGAP9,SIK3,TEK,TLR4,ERCC6L2,NPL,TRIO,DCBLD1,VAV1,WIPF1,NPDC1,AMZ1,INTS3,GDPD5,ADAMTS9,PLD4,RGS7BP,FAM13C,DOCK8,MSRB3,SPATA13" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.28E-10 4.02E-06 9.59E-09 8.70E-08 46 172 "RNF157,INTS2,TAOK1,LCORL,PKP4,BACH1,RUNX1T1,CDH2,ZNF445,SLIT2,RBM39,TCAF1,AIF1L,ZC3H11A,EIF4G1,SRRM1,SMC2,APOPT1,TUBGCP4,LPAR4,CHIC1,MEIS2,MMP16,MSI1,CEP97,C1orf54,PBRM1,TMLHE,PCMTD2,MEG3,TRA2B,SLC12A2,CPEB4,ZC3H13,TROVE2,CLSTN2,SYNE2,CBX5,R3HDM1,SSBP2,FLRT2,ZNF711,TRIM9,ADAMTS9,GAN,SENP7" Coexpression Atlas Lungmap Mouse Lung E16.5 Endothelial Subtype Mature Endothelial Lungmap Mouse Lung E16.5 Endothelial Subtype Mature Endothelial Lungmap CCHMC 8.80E-10 4.27E-06 1.02E-08 9.22E-08 85 421 "RALGAPA1,CCDC85A,ZNF608,SPARCL1,APBB2,APOC1,SHROOM2,PRX,ARRB1,ATP1B3,ADAM15,ARHGEF7,SGCE,SPAG9,SCARB1,ARHGEF2,CNOT8,QKI,CDC42BPB,CREM,LRRC3B,GIT2,ARMCX4,PITPNC1,SLC12A6,EDIL3,EDN1,KLHL5,PHF20L1,APH1A,PLEKHA1,ARMCX1,CORO2B,ST3GAL6,NBEA,PDLIM5,TRIM16,FYN,INPP5K,KIAA1841,GGTA1P,TOX3,DCLK2,GPD2,STMN2,ADAMTS13,GSTM5,MAP4K5,PACSIN2,AGFG1,ITPKB,SMAD1,MEIS2,KITLG,PDE4B,ABCB1,PLEC,PLTP,DRAM2,GDPD1,WBP1L,SNRK,TMEM255A,FAT4,RAP1GDS1,MAPK12,ZNF821,BTBD3,GKAP1,CEP68,RGL1,SYNE2,MMS19,TAL1,TCF4,SIN3B,ZEB1,DOCK9,DICER1,HEY1,LRRC8A,SH3GLB2,MPPE1,FAM13C,NHSL1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 9.57E-10 4.65E-06 1.10E-08 1.00E-07 28 77 "TMCC3,SYT13,APC,ZSCAN18,ARHGEF7,CALB1,CHGB,AKAP6,JAKMIP2,TMEM35A,STARD3NL,EVL,NSG1,FYN,GNAO1,STMN2,NEGR1,CELF5,LSAMP,KITLG,NRCAM,SNX10,ZFHX4,RTN1,PEG10,SEPT3,VGF,CELF4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 9.67E-10 4.69E-06 1.11E-08 1.01E-07 95 491 "USP31,PTCHD1,MARCH4,GPRASP2,AMPD2,APOC1,CPNE5,LGR5,SEMA4G,MADD,IGDCC4,RGS20,ATP1A3,BARD1,GPC2,LDLRAD4,CA12,CACNA1A,HAP1,CDC25B,MYL6B,CNTFR,PCYT1B,LETMD1,CRYBB1,CLIP3,CSF2RA,DNAL1,ACOT8,MBNL2,APC2,BAIAP2,ZMYND15,NBEA,HIGD1B,SRRM4,RAB30,STARD3,LOXL3,PCLO,FRMD5,HLF,TCEAL6,CELF5,IGF1,LRRTM1,KCNH2,L1CAM,LSAMP,SMAD9,MAP2,KITLG,SAMD5,N6AMT1,HS6ST3,MXI1,MYH3,NPY,NUCB2,PAX6,PDE3A,PDE4D,PFKFB2,ZFYVE21,DIRAS2,MASP1,TMEM231,GAL3ST4,PRRT2,MORC4,CNKSR2,SNAP25,DOP1A,UNC5B,ARHGAP26,CDK19,NKAIN2,SEPT3,ARHGEF9,PLCB1,ANKRD12,PHF24,HIF3A,SLC44A1,NACC2,NR2E1,ANKRD24,STXBP4,UCHL1,MGAT5B,PLPPR2,CCDC136,NPDC1,ZNF23,SENP7" Coexpression Atlas Arv_EB-LF_1000_K4 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 1.03E-09 4.98E-06 1.18E-08 1.07E-07 87 436 "PCDH19,KCTD16,SORCS2,DPP10,LRCH2,LGR5,RNF182,MYRF,CALB2,CABP7,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,CNTNAP2,LYPD1,SNAP91,SPOCK3,DLX1,DPP6,EDIL3,EDN3,SEMA3D,ADGRV1,CLVS1,TMEM132C,HPCAL4,PSD2,CHL1,SRRM4,CPLX2,GFRA2,FREM1,CCDC184,STMN2,GRIA2,C1QL4,BACH2,IGFBPL1,CELF5,C2orf72,SLC6A17,INSM1,CDH20,CLEC18A,NNAT,NPY,NTRK2,PAX6,PCDH8,PDZRN4,SDK2,NECAB2,MAGEL2,NKAIN4,PRPH,PSD,LAMA1,ELOVL2,PTPRN,PTPRO,TMEM255A,ZFHX4,HUNK,KCNIP1,RTN1,LRFN5,TNFRSF19,TMEM200C,PKNOX2,TRIM67,DMRTC1,SNAP25,CLSTN2,SST,SYT5,PCDHGB6,ASXL3,RIMBP2,DOK6,ZIC1,CRB2,DPYSL5,DNAH10,FAM13C" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.05E-09 5.11E-06 1.21E-08 1.09E-07 75 355 "WDR35,ARHGAP20,CASK,TMEM108,MPDZ,CACNA1G,MYRF,CACNA2D1,KALRN,CBLN1,AP4M1,LARGE1,SLIT2,CNTFR,AKAP7,CLIP3,VCAN,BOC,ARMCX2,HEPH,DNM1,EDNRA,MEX3B,FLNC,FREM1,GHR,GLI2,ADAMTS6,GUCY1A1,GUCY1B1,HAS2,NKD1,MATN2,CHIC1,MEIS1,MEIS2,MMP16,TCEAL5,ZC3H12B,NEFM,NNAT,NME4,PDE3A,PIK3R1,PCDH18,SH3KBP1,LAMA1,PTN,ZIK1,PTX3,RIC8B,RNASEL,ROBO2,ARMH4,MEG3,ZNF354C,CCDC112,SATB1,DZIP1,PKNOX2,ZNF334,PDZRN3,SOX11,KLHL7,CUX2,ASXL3,TPM1,STXBP4,TRPS1,SSBP2,PLEKHH2,VLDLR,ZFP37,ZNF184,ST8SIA2" Coexpression Atlas gudmap_developingGonad_e11.5_testes_1000 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.10E-09 5.35E-06 1.26E-08 1.14E-07 143 843 "DGCR6,ABCF1,ACTN1,KDM5D,ADD1,AK2,OGT,EPB41L5,APLP1,CASK,NUMB,BACH1,MYRF,DDR1,CALB1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,ARHGEF2,ARHGAP33,LHX2,COL9A1,ZNF385A,RBM39,CRMP1,HAPLN1,RNF14,CLIP3,CSNK1E,PUM1,KIAA0408,ARHGAP32,TCAF1,DAPK1,DAPK3,DBI,DBN1,DCTN1,GSDME,ALKBH8,RCAN1,DNM1L,EDNRA,MBNL2,EIF4G1,EMX2,EPB41L2,KATNAL1,TUBB3,PRMT5,SEC24B,FGFR1,MEX3B,SYNCRIP,ZBED3,DLL3,AHDC1,DHRS4,TCERG1,TOX3,KIAA1958,LPAR4,GPR37,STMN2,GRB10,BACH2,SMAP1,NKD1,INSM1,SMAD1,MAPT,CHIC1,MEIS2,TAGLN3,NEFM,NELL2,NNAT,PALM,GNG2,OLA1,PIK3R1,PKM,SLC25A23,PCDH18,EXOSC10,PPP2R5E,PRKACB,ZIK1,PTPRG,GAL3ST4,FIGN,UBR7,ZFHX4,MEG3,ATAT1,ATXN2,HES6,SEC14L1,ARX,SHMT2,WDR37,ZKSCAN3,SMARCA4,SNAP25,SNRPN,SOX11,RBM26,SPART,TROVE2,SULF2,JMJD6,PRRC2C,SYNE2,PJA1,FBXW11,KLHL4,TCF4,TRIM2,USP22,CLASP1,PUM2,TMEM9,ASXL3,TNS1,TRIO,STXBP4,TSC2,TST,TTC3,UCHL1,USP1,CLDND1,ZIC1,ZFAND5,INTS3,STOX2,VPS35L,PCBP4,RTN4,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.14E-09 5.53E-06 1.30E-08 1.18E-07 62 271 "RNF157,LTBP4,GPRASP2,PHYHD1,USP37,ADAM23,LONRF2,IGDCC3,AATK,PHF14,HDAC9,SCRN1,JAKMIP2,RUSC2,DDX46,DLX1,DMD,SHANK1,CASP8AP2,DTNA,MAMLD1,TMEM35A,EPB41,APC2,NSRP1,CHST15,AFF2,PPARGC1A,MAP7D2,USP51,NEGR1,CREG2,TM6SF1,TAGLN3,NCAM2,NELL2,PCDH9,SEMA5B,TMEM38A,POU6F1,DIRAS2,ENOX1,RBBP8,MEG3,STX1B,FHOD3,NLGN1,CCDC88A,SMARCD3,SOX11,UHRF1BP1L,CLSTN2,RHBDL3,CUX2,USP1,TSPAN11,LYPD6,ZNF184,SPIRE1,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.23E-09 5.95E-06 1.39E-08 1.26E-07 27 73 "ASIC1,APC,THSD7A,RUNX1T1,NRXN3,EBF1,KMT5B,EMX2,NRN1,TUBB3,GAD1,GNAO1,STMN2,GRIA2,CELF5,INSM1,MAP2,MEIS2,TAGLN3,NNAT,MEG3,RTN1,SEPT3,SYT1,TAL1,NDRG4,CELF4" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.25E-09 6.05E-06 1.41E-08 1.28E-07 56 234 "GALNT13,RNF150,C1QTNF3,ALCAM,ABCD2,DPP10,DOCK11,IL33,THSD7A,LDB2,LRIG1,RASSF2,EBF1,EDN3,EDNRA,SEMA3D,TMTC1,EGFR,ADGRV1,CORO2B,SLC37A3,IQGAP2,GGT5,GPR12,GUCY1B1,RASSF8,HNMT,MSL1,IFI16,KCND2,LSAMP,MMP17,NOVA1,PDE4B,GPR85,PIK3R1,PLCL1,PCDH18,SH3KBP1,LRRN3,RELN,FAT4,FIGN,CSRNP3,SCN7A,ST8SIA1,ITPRID2,NXT2,RGL1,RHBDL3,PCDHB9,TLR4,TRO,SSBP2,PCDH20,PLSCR4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K2 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.27E-09 6.19E-06 1.44E-08 1.31E-07 116 644 "EMILIN3,HECW2,RTL9,SEMA6A,KCNAB2,CDK10,IGDCC4,SPTBN4,RASL11B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDO1,CRLF1,DIS3L,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,BOC,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,MBNL2,LRRC17,DENND4A,HSPA12B,DLC1,FDFT1,SCARA3,FOXF2,SYT3,ZBED3,TRIM16,NSG1,STAU2,TVP23A,ZMAT1,TRAF3IP2,ZNF274,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,BACH2,SYNPO,AGBL5,IDH3B,ITPKB,JAK2,CREG2,LAMA2,LAMP2,SMAD9,MAN2A2,MBNL1,SRSF12,N6AMT1,FXYD7,NFIX,NPY,ZNF827,CNTN3,PDE3A,PDE4D,PFKFB2,EPB41L4B,TATDN3,CCDC144B,DIRAS2,CNTLN,IQSEC3,FAT4,BEND5,ZFHX4,MRAP2,SH3GL3,CNKSR2,DZIP1,SLC8A1,SMARCC2,IFT122,LIMCH1,PDZRN3,CDK19,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,TCF4,SATB2,SYNE1,PHF24,CRTC1,HIF3A,ASXL3,ANKRD24,PIK3R5,SYNPO2,TRPS1,TSPAN11,WIPF1,ZNF32,FTSJ1,ADAMTS10,KLHDC1" Coexpression Atlas BM Top 100 - accumbens BM Top 100 - accumbens Body Map 1.35E-09 6.54E-06 1.52E-08 1.38E-07 28 78 "ADORA2A,CPNE5,CALB1,CDR1,LHX2,NGEF,CNR1,DGKB,PLPPR4,PPP1R1B,GABRG2,GAD1,CYP46A1,GNAL,CELF5,SOWAHA,NPY,PCDH8,PPP3CA,PRKCB,MEG3,SLC8A1,DDN,SST,RASD2,LAMP5,KCNAB1,MPPE1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.37E-09 6.66E-06 1.55E-08 1.40E-07 58 247 "GALNT13,HECW2,PCDH10,FAM135A,LCORL,RUNX1T1,CBLN1,CDH2,DCLK1,CDO1,SLIT2,PLAA,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,HDAC9,PITPNC1,SPOCK3,EDNRA,EGFR,TENM1,SCML2,FOXF2,NBEA,MEGF10,TOX3,RAB40B,LPAR4,GRIA2,IFI16,LSAMP,MYH3,PCDH8,NLGN3,ING3,ZIK1,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,SATB1,CSRNP3,TROVE2,TTBK2,KLHL7,ADGRL3,PCDHB15,PCDHB3,PUM2,SSBP2,UGT8,PCDH20,ZBTB14,PARP11,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.44E-09 6.99E-06 1.62E-08 1.47E-07 80 391 "AXIN2,USP31,PCDH10,SYT13,APC,TNRC6C,CADPS,INSYN2B,RNF182,NRP2,DST,CH25H,RUNX1T1,CBLN1,RGN,DCLK1,CDO1,CRLF1,FOXN3,CNR1,ZNF521,VCAN,ERC2,SCRN1,TIAM2,DLX1,DNM1,DYNC1I1,EDNRA,TENM1,EYA1,TMEM132C,FOXF2,SYNCRIP,NBEA,MEGF10,CHL1,GFRA2,GNG4,GRIA2,RASSF8,BACH2,IFI16,ASPRV1,MEIS2,MYH3,NDP,CNTN3,KANSL1,PTPRG,PTPRO,ZFHX4,ROBO1,ROBO2,CCDC112,SALL1,CSRNP3,ANKRD6,LIMCH1,SOX11,ZHX3,CLASP2,ADGRL3,TCF4,SATB2,PCDHB7,ASXL3,ERCC6L2,KAT6B,SYNPO2,TRPS1,RPRM,UGT8,FLRT2,WNT7A,PCDH20,KCNAB1,FAM13C,MSRB3,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.47E-09 7.15E-06 1.65E-08 1.50E-07 21 47 "DPP10,ADAM23,CACNA1B,CNR1,COL9A1,PLCXD3,GRIN3A,TUBB3,SYT17,GFRA2,MAP4,NDP,NTRK2,CLDN11,MAPK10,PRPH,PTPRO,RGS4,RTN1,SNAP25,CUX2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.55E-09 7.54E-06 1.74E-08 1.57E-07 72 338 "NDRG2,SPARCL1,SEMA6A,PCDH10,CCDC146,PCDHGB4,BARD1,MIR9-3HG,CA12,HIP1R,SPAG9,PRC1,SEPT7,CDC25B,CDO1,CDR1,QKI,AKAP7,COL9A1,SNCAIP,LRIG1,CST3,ARHGAP32,RASSF2,DBI,LYPD1,ZNF582-AS1,DPP6,DTNA,EDNRB,EGFR,TNK2,LRRC17,ADGRV1,FAM198B,FGFR3,PDLIM5,CSPG5,GABRG1,GATM,DCLK2,HAS2,CFAP126,C2orf72,LIFR,NFIX,NTRK2,ENPP2,PLXNB1,LRRN3,NKAIN4,HYDIN,MASP1,PTCH1,SPDL1,PTN,TMEM231,ZCWPW1,KLHDC8A,MEG3,SALL1,LIMCH1,KANK1,SULF2,WSCD1,TCF4,HEY1,TMPO,CABIN1,TMEM161B-AS1,USP1,TFIP11" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_500 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_500 FaceBase_ST1 1.56E-09 7.59E-06 1.74E-08 1.58E-07 75 358 "ACADM,PCDH19,TAOK1,ABCD2,APBA2,UPRT,RNF182,RAB29,ISPD,PRC1,CLDN10,LHX2,RAB33A,CLCN3,QKI,CNTNAP2,SCRN1,JAKMIP2,GSDME,DLX1,EFCAB2,CSPG5,KIAA1841,IGSF5,GNAO1,LPAR4,RNF165,SOX21,UBE2QL1,IGFBPL1,USP51,TCEAL6,INSM1,LRRTM1,LSAMP,MEIS2,LYRM9,MYO9A,NEFM,NELL2,NOVA1,PAX6,SLC10A4,STRN3,SCHIP1,MINDY2,NKAIN4,PKIA,GDPD1,PTX3,TUG1,TSPY26P,PBRM1,HSPA4L,KIF21A,SH3GL3,SLC4A3,TET1,TROVE2,ELOVL4,ADAMTS17,SLC35G2,CCDC173,C18orf54,HEY1,NR2E1,C9orf85,TRPS1,WNT7A,XRCC4,ATP6V0E2,STOX2,PARP11,AMN1,NETO2" Coexpression Atlas PCBC_ratio_Sex-Associated_Pluripotency-Differentiation-2X-p05 Sex-Associated_Pluripotency-Differentiation-fold2.0_adjp0.05 PCBC_AltAnalyze 1.62E-09 7.85E-06 1.80E-08 1.63E-07 106 574 "ASIC1,KDM5D,ADCY5,ADCY8,ESYT2,KLHL13,PCDH19,ZNF578,PDZD4,AMH,LRCH2,APOC2,ZFYVE28,PLA2G4C,PCDHGB4,CA4,CCK,RGN,SYNGR3,KCNAB3,CLGN,ABCG2,FAM19A5,ZFP28,IPCEF1,PYGO1,ELMO1,KIAA0319,HS3ST2,SHANK1,DPP6,MAMLD1,PHC2,OPTN,RGS17,ENO2,RAB9B,CEP85L,ETV1,ZNF585B,CORO2B,DLC1,DLL3,CHL1,GATM,ALDH1L1,ADAM28,TTBK1,DCLK2,STMN2,GRM8,RNF165,GSTT2,ATOH8,HBA1,CELF5,ITGAM,ZNF667-AS1,MAP6,MATK,SHC3,ZNF680,TAGLN3,ZNF862,NEFH,NFIX,NNAT,PCDH8,PDE1C,CYTL1,TRHDE,NECAB2,FA2H,SH3KBP1,MAPK10,PTX3,TMEM255A,DUSP15,MORC4,KLHDC8A,MEG3,ZNF568,LRFN5,SCN7A,ZNF667,SOX3,SOX15,LMO3,SSTR2,SYT5,ZNF571-AS1,ZEB1,PCDHGA6,PCDHGA4,PCDHB3,TEK,RUNDC3B,ANKRD20A2,TTTY15,OSBP2,VGF,ZIC1,EML6,LAMP5,GJC2,NLRP3" Coexpression Atlas Lungmap Mouse Lung E16.5 Endothelial Lungmap Mouse Lung E16.5 Endothelial Lungmap CCHMC 1.66E-09 8.08E-06 1.85E-08 1.68E-07 89 454 "CCDC85A,ZNF608,HECW2,SPARCL1,SEMA6A,SHROOM2,ATP1B3,ADAM15,SPAG9,LDB2,SCARB1,CD38,ARHGEF2,CNOT8,ABCG2,CDC42BPB,CRMP1,HAPLN1,ABCG1,PPP1R16B,ARMCX4,PITPNC1,DPYSL2,EDIL3,EDN1,KLHL5,PLEKHA1,CALCRL,FAM198B,CORO2B,ST3GAL6,FLT1,TRIM16,ST6GALNAC3,FYN,PCDH17,GGTA1P,LYVE1,TOX3,LPAR4,STMN2,MAP4K5,AGFG1,ICA1,KIT,STMN1,LIMS1,LMO2,SMAD1,TM6SF1,MEF2C,MEIS2,MEST,KITLG,LAYN,PDE4B,ABCB1,MAPK3,GDPD1,SNRK,PTPRB,TMEM255A,SH3TC2,C1orf54,RAP1GDS1,RPS6KA2,SCN7A,SGK1,MYO18A,PREX2,BTBD3,UNC5B,SPTAN1,THSD1,RGL1,SYPL1,TAL1,KLHL4,TCF4,ZEB1,DOCK9,TEK,HEY1,LRRC8A,CA14,NPDC1,SH3GLB2,GDPD5,NHSL1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.74E-09 8.46E-06 1.93E-08 1.75E-07 41 147 "PCDH10,SYT13,INSYN2B,CH25H,RUNX1T1,ANKRD44,PYGO1,HDAC9,EDNRA,SEMA3D,EGFR,ETV1,EYA1,TMEM132C,MEX3B,FOXF2,MEGF10,IQGAP2,TOX3,LPAR4,IFI16,GPR85,NLGN3,PCDH18,TRHDE,PTPRG,TMEM255A,ZMAT4,TSPY26P,ZFHX4,ROBO1,SALL1,SATB1,CSRNP3,TNFRSF19,DZIP1,ARHGEF9,ADGRL3,PCDHB3,TRPS1,SOCS4" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.78E-09 8.63E-06 1.97E-08 1.78E-07 100 532 "METAP1D,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,SPTBN4,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,ZNF599,SCAPER,GPC2,LDLRAD4,KCNAB3,CDO1,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,DGKG,TIAM2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,ARMCX1,PTK2B,ZBED3,DLL3,STAU2,ABLIM2,FYB1,ZMAT1,GAA,GHDC,TMEM8B,GHR,LYVE1,GNG4,GRIK4,GUCY1B1,TCEAL6,ICA1,SCIN,KLHL23,GPR155,MID1,MITF,N6AMT1,MYH3,NEXMIF,TCEAL5,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,DIRAS2,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,MORC4,PRIMA1,MRAP2,STK32B,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,ASAP3,SMARCC2,ARHGAP26,IQSEC2,NKAIN2,ADGRL3,FAM189A1,CRTC1,LRRC24,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas PCBC_SC_CD34+_1000 Progenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_1000 PCBC 1.81E-09 8.80E-06 2.00E-08 1.81E-07 161 987 "SYN3,TMEM132B,ADCY5,ADCY8,GALNT13,ADD2,UNC5A,SEMA6A,SYT13,PDZD4,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,PROM1,GYG2,CACNA1G,HAP1,CLDN10,CCK,MTMR7,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,FAM19A5,SULT4A1,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,MYRIP,IGDCC3,LRRC3B,RIMS4,CNTNAP2,FAM169A,PPP1R16B,ERC2,SEC14L5,RIPOR2,KIF26A,KCTD8,BRINP1,AIF1L,JAKMIP2,DGCR5,PLPPR4,CHRDL1,HS3ST2,SEZ6L2,HEYL,AASS,RASGRP2,PIPOX,ADGRV1,PPP1R1B,OLFM1,HPCAL4,SYT3,CSPG5,NSG1,MEGF10,HRASLS5,GABRA3,GABRB3,GFRA2,LUZP2,GNG4,LPAR4,SOX21,LINGO1,PSIP1,IGFBPL1,C9orf129,CELF5,ZIC5,KCND2,KIF5A,CAMK2N2,MATK,CHST6,SCAMP5,ADAM22,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,PCBP3,SEMA5B,JAKMIP1,PNMA3,PSAT1,MAGEL2,EPB41L4B,FA2H,PPP2R2B,NKAIN4,LAMA1,GDPD2,TMEM145,NKAIN1,RASGRF2,KHDRBS2,ZMAT4,RET,RORB,MRAP2,HUNK,SALL1,TMEM200C,SH3GL3,PPM1E,CNKSR2,SEPHS1,MAST1,SNRPN,SOX3,SOX15,NMNAT2,HECW1,SOX21-AS1,SEPT3,SYN1,ARC,SYP,SYT1,COBL,TACR1,FAM189A1,SLC19A3,RNF175,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,RASD2,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,SLC30A3,CADM2,GAL3ST3,RGS7BP,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.96E-09 9.50E-06 2.15E-08 1.95E-07 50 200 "KLHL13,CC2D2A,IGDCC4,TMEM108,MYRF,DCLK1,AKAP5,ZNF521,CLIP3,PLXNA4,BOC,DNM1,DRP2,C8orf37,EMX2,MTSS1L,NRN1,MEX3B,FLNC,NSG1,TRAF3IP2,TCEAL6,IGF1,NKD1,KCND2,KLHL23,MAP2,MATN2,MEIS1,NEXMIF,NNAT,NME4,PCDH18,PTPRD,REV3L,MEG3,HUNK,ZNF354C,CCDC112,SATB1,RASA3,PDZD2,PEG10,ST5,ADGRL3,ZFPM2,ASXL3,TRPS1,PLEKHH2,ZFP37" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_500 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 2.07E-09 1.01E-05 2.27E-08 2.06E-07 95 498 "ADD2,VAT1L,ATP1A3,LDHD,CA8,CLDN10,DCLK1,UBE2L6,CHGB,RAB33A,ABCG2,PCYT1B,CABP1,LRRC3B,GALNT9,RIMS4,FAM131B,SEC14L5,HDAC9,JAKMIP2,PARD6A,CHRDL1,HS3ST2,EDIL3,AASS,TMEM35A,LRRC17,RASGRP2,ETV1,PIPOX,PPP1R1B,OLFM1,HPCAL4,FLT1,NSG1,TOX3,GNAO1,GNG4,CCDC184,LPAR4,LINGO1,INSYN1,SHISAL1,KCND2,KCNN2,KHK,KIF5A,CAMK2N2,MAP2,PPM1L,MX1,FXYD7,NEFM,NELL2,NOVA2,NPTX2,NTRK3,PCSK1,TMOD2,FXYD1,PCDH18,SCHIP1,PRKCB,KLK6,GDPD2,PTPRN,PTPRN2,PTPRO,TMEM145,RASGRF2,RORB,PPM1E,NLGN1,SOX3,NMNAT2,SPP1,LMO3,RHBDL3,ARHGEF9,ARC,SYP,SYT1,SLC19A3,PCDHAC2,ENHO,TIMP4,ANKRD24,RASD2,VGF,VSNL1,LGI4,CRB2,DPYSL5,LAMP5,TMEM63C" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.13E-09 1.03E-05 2.33E-08 2.12E-07 81 401 "METAP1D,ADCY8,USP31,AMPH,APC,VAT1L,SFMBT2,SEMA4G,ZSCAN18,BMP7,IL33,CACNA2D1,CACNB4,CH25H,FAM19A5,COL9A1,ZFP28,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,KATNAL2,SPOCK2,RAB39B,DYNC1I1,DTNA,HEYL,TMEM35A,EIF1,EYA1,ST3GAL6,FGF1,FGFR1,SCARA3,PRELID3A,MEGF10,GABRB3,BRD8,KIAA1958,FUT10,GRB10,PRDM5,FAM19A2,FAM107A,HAS2,FRMD3,NEGR1,MSI1,OXTR,CNTN3,PRTG,ANKRD16,KANSL1,CEP41,PPP2R3C,ENOX1,GAL3ST4,CRTAC1,REV3L,ROBO2,RPS20,SALL1,MAPK12,ZFP2,SUPT20H,TRA2B,HSPA4L,ANKRD6,SLC12A2,NEK4,CAMTA1,ERCC6L2,TPM2,SSBP2,ZNF184,ZFAND5,INTS3,PCBP4,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE76381_iPSMoleculeCountsPMLog2 2.17E-09 1.06E-05 2.38E-08 2.15E-07 41 148 "XKR4,TMEM132B,TMCC3,PCDH10,SYT13,APC,ZSCAN18,ARHGEF7,CALB1,RUNX1T1,CHGB,AKAP6,JAKMIP2,TENM1,TMEM35A,STARD3NL,EVL,NSG1,FUT9,FYN,TOX3,GNAO1,GNG4,STMN2,NEGR1,CELF5,LSAMP,KITLG,HS6ST3,NRCAM,SNX10,RET,ZFHX4,RTN1,PEG10,LMO3,SSTR2,SEPT3,VGF,CELF4,CADM2" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap CCHMC 2.24E-09 1.09E-05 2.44E-08 2.21E-07 78 381 "NCKAP5,NDRG2,ADD1,AGT,ALCAM,ABCD2,OGT,APBB2,APOC1,PPP4R4,NRP2,MTMR3,CACNA1G,CACNB4,CAST,CLDN10,SEPT7,CDO1,ABCG2,RBM39,CNTNAP2,PPP1R16B,KIAA0040,MYADM,DAPK1,GIT2,DMPK,RCAN1,DTNA,ABCC5,FAM13A,PLEKHA1,RGS17,PCOLCE2,CALCRL,RASGRP2,DLC1,CHST15,CPLX2,GHR,GLUL,STON1,PARD3B,GSN,GSTM5,IRF8,IL6R,IL6ST,MAN2A2,MAPT,MEIS1,NRCAM,NTRK2,PIK3R1,FXYD1,FITM2,VPS13C,MTMR10,PID1,ACSS3,SH3TC2,SUGCT,ROBO2,RYR3,SCN7A,FNIP1,ZFP30,PREX2,SLC12A2,NXT2,PCDHGA6,SYNE1,HIF3A,PLEKHH2,VIPR2,LYPD6,GAL3ST3,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.27E-09 1.10E-05 2.47E-08 2.24E-07 85 429 "GALNT13,HECW2,PCDH10,FAM135A,SYT13,LCORL,VAT1L,CADPS,INSYN2B,RNF182,ADAM23,DST,LDLRAD4,RUNX1T1,CBLN1,CDH2,DCLK1,CDO1,SLIT2,PLAA,CNR1,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,HDAC9,PITPNC1,SPOCK3,DLX1,EDNRA,EGFR,TENM1,EYA1,TMEM132C,SCML2,UBE2E3,FOXF2,NBEA,MEGF10,TOX3,RAB40B,LPAR4,GRIA2,MAP4K5,NEGR1,IFI16,LSAMP,MYH3,PCDH8,GPR85,NLGN3,TRHDE,ING3,ZIK1,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,SALL1,SATB1,CSRNP3,ANKRD6,SLC14A1,LIMCH1,SOX11,TROVE2,ELOVL4,TTBK2,KLHL7,ADGRL3,TCF4,PCDHB15,PCDHB3,PUM2,ERCC6L2,SYNPO2,SSBP2,UGT8,PCDH20,ZBTB14,PARP11,FAM13C,SOCS4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.43E-09 1.18E-05 2.64E-08 2.39E-07 161 991 "ABCF1,AXIN2,PLEKHH1,PTCHD1,INTS2,KIAA1324,TAOK1,EPB41L5,ATP1A1,ATP2A2,DOCK11,TTLL9,NRP2,ZNF599,PROM1,CA4,CA12,HAP1,CBLN1,TBRG4,CLCN3,FAM19A5,CNTFR,IGDCC3,CDC42BPB,CRMP1,CRYM,FAM169A,SLITRK5,CTH,GREB1,RIMS2,KATNAL2,DAPK3,JAKMIP2,DDX46,CHRDL1,DTNA,PLXNC1,EIF4G1,PLEKHA1,CERCAM,EPHB1,PIPOX,RRAGB,EXTL2,ADGRV1,CD320,REEP2,ACSL4,CEP78,SPSB4,FGF12,FHL1,SEMA4D,NOP56,PDLIM5,DLL3,FUT9,GABRB3,MTHFD2,SRRM4,AHDC1,TXNL4A,TCERG1,TOX3,MAP7D2,LPAR4,PCLO,STMN2,CIT,RNF165,SOX21,TOX2,FRMD5,DDX19B,ELOVL5,USP51,CELF5,NKD1,ZIC5,LRRTM1,SLC35G1,CDH20,KIT,IPO5,KTN1,AQP11,TM6SF1,MSI1,MYCN,NNAT,NOVA1,NRCAM,NTRK2,PRTG,FAM98B,NLGN3,SEMA5B,PKM,SLC25A23,PLTP,MAGEL2,POLR2F,IRX1,PPP5C,MAPK10,PRODH,LAMA1,GDPD2,ELOVL2,PTPN13,EML5,CCDC40,SUSD4,FIGN,RPL15,RTN1,SALL1,TNFRSF19,HSPA4L,KIF21A,SHMT2,FHOD3,NUBPL,PKNOX2,SNRPN,BDP1,DOK5,NMNAT2,LMO3,PBLD,NEK4,KANK1,SYN1,SYP,SYPL1,ANKRD28,MTCL1,MCF2L,WSCD1,TMEM121,ZNF106,BEX4,CA14,HSPBP1,UBE3A,MGAT5B,VSNL1,RBFOX3,ZIC1,ZIC2,KCNT2,DPYSL5,LAMP5,SLC38A1,PCBP4,FZD3,AAAS,FXR1,SPATA13" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.59E-09 1.26E-05 2.80E-08 2.54E-07 32 100 "CCDC85A,PCDH10,LTBP4,GPRASP2,APLP1,ADGRB3,RUSC2,EDNRB,EMX2,ENO2,ADGRV1,PPARGC1A,MAP7D2,TDRKH,TOX2,NCAM2,NEFM,NELL2,PAX6,PCDH9,SEMA5B,POU6F1,RTN1,SMARCD3,WSCD1,PLPPR2,ZIC1,TMEM237,DPYSL5,WNK2,KLHDC1,SENP7" Coexpression Atlas PCBC_SC_fibroblast_1000 Progenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 2.62E-09 1.27E-05 2.83E-08 2.56E-07 161 992 "KCNH8,SYN3,TMEM132B,ADCY5,GALNT13,ADD2,UNC5A,PTCHD1,SEMA6A,PDZD4,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,AZGP1,ADGRB1,LDHD,CBS,CLDN10,CCK,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,FAM169A,SEC14L5,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,HS3ST2,SLC25A18,FAM78B,AASS,RASGRP2,PIPOX,ADGRV1,PPP1R1B,OLFM1,SPSB4,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,SRRM4,IGSF5,GFRA2,LUZP2,GNG4,LPAR4,GRIK5,GRM8,LINGO1,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,ITGAM,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KHK,KIF5A,CAMK2N2,MATK,CHST6,SCAMP5,TCEAL5,FXYD7,NELL2,NPTX1,NLGN3,SEMA5B,JAKMIP1,NECAB2,MAGEL2,EPB41L4B,FA2H,PPP2R2B,NKAIN4,SMIM10L2B,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,FAM184A,ZMAT4,RET,LGI2,RORB,MRAP2,SGSM1,HUNK,SALL1,TMEM200C,SH3GL3,PPM1E,CNKSR2,SEPHS1,TET1,OGDHL,SOX3,SOX15,NMNAT2,SOX21-AS1,SEPT3,RHBDL3,ARC,COBL,KLHL4,FAM189A1,SLC19A3,PCDHA6,PCDHA3,PCDHA2,RNF175,CHST8,GALNT17,ENHO,RELL2,FAM124A,ANKRD24,PIK3R5,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,TMEM198,DPYSL5,SLC30A3,CADM2,GAL3ST3,RGS7BP,NETO1,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k2_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.72E-09 1.32E-05 2.93E-08 2.66E-07 30 90 "APLP1,LHX2,CRMP1,CSNK1E,GSDME,TUBB3,DLL3,TOX3,KIAA1958,STMN2,BACH2,INSM1,MAPT,TAGLN3,NEFM,NNAT,GNG2,ZIK1,NKAIN1,GAL3ST4,ZFHX4,ATAT1,SNAP25,SNRPN,SOX11,TRIM2,CLASP1,ZIC1,MEIS3,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k4 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.73E-09 1.33E-05 2.94E-08 2.66E-07 52 214 "HECW2,APAF1,USP37,RNF182,ADGRB3,SGCE,LDLRAD4,RUNX1T1,CDH2,CDO1,NRXN3,ZNF521,NSL1,FAM171B,ANKRD44,ARMCX4,TIAM2,RHOBTB1,GOLT1B,E2F6,ASB3,ETV1,TMEM132C,MEX3B,FOXF2,TVP23A,MEGF10,PCDH17,STMN2,GUCY1A1,NEGR1,IFI16,MEIS2,NDP,PCDH8,GPR85,PFKFB3,PCDH18,LRP12,CEP41,RGS4,ZFHX4,C12orf49,TRA2B,LIMCH1,CMTR2,ZC4H2,PCDHB15,PCDHB7,ASXL3,TMPO,RPRM" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.75E-09 1.34E-05 2.96E-08 2.68E-07 46 178 "USP31,TAOK1,DPP10,CADPS,NRP2,CACNA1B,CACNA2D1,CHGB,CNR1,CNTN1,MYRIP,VCAN,PLCXD3,MFAP3L,GRIN3A,EYA1,DLC1,FOXF2,CHL1,STMN2,FAM19A2,IFI16,MAP4,MMP16,NCAM2,NEFM,NTRK2,CLDN11,SLC10A4,GPR85,NALCN,MAPK10,PRPH,RET,RGS4,ZFHX4,RTN1,CSRNP3,ST8SIA1,NAPB,SNAP25,CUX2,ERCC6L2,RGMB,TRPS1,RPRM" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Lungmap CCHMC 2.86E-09 1.39E-05 3.06E-08 2.77E-07 85 431 "ACTN1,NDRG2,AGT,WDR35,SPARCL1,LCORL,CASK,CHRD,BCHE,DST,SYNJ2,CACNA1G,RUNX1T1,DCLK1,NOG,NRXN3,ABI3BP,FAM171B,CLIP3,GPSM1,EDNRB,TMTC1,ELN,LRRC17,NCALD,ETV1,FCGRT,POLK,FOXF2,MEGF10,GHR,SPIN1,GPER1,GRB10,PRDM5,ADAMTS6,GUCY1A1,GUCY1B1,CPT1C,SHISAL1,IGF1,NKD1,KCNK3,KCNN2,TTYH2,LAMA2,MEIS1,SAMD14,NBL1,NFIX,NNAT,NPR2,PALM,ENPP2,BCAS3,PTCH1,PTH1R,RGS4,ROBO1,ROBO2,MEG3,SEMA6D,TNFRSF19,NLGN1,DZIP1,SIRT2,TRIM67,TET1,ZNF667,FAM126B,ZHX3,ERC1,PHLDB1,STX1A,KANK1,SULF2,TPM1,TPM2,SYNPO2,TRPS1,ZKSCAN5,VSNL1,ZNF32,MSRB3,ADAMTS10" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.86E-09 1.39E-05 3.06E-08 2.77E-07 85 431 "RNF157,FAM135A,AMPH,EPB41L5,VAT1L,CASK,ADAM23,BMP7,KALRN,PTBP2,CDH2,TBRG4,FAM189A2,MAP4K4,COL9A1,CRMP1,CRYM,PPP1R16B,CTH,KATNAL2,SPOCK2,BRINP1,SNAP91,GRIN3A,RAB39B,DUSP9,SLC43A2,EYA1,SPSB4,FGFR1,PSD2,HVCN1,PRELID3A,TVP23A,MEGF10,CHL1,DENND2A,GALC,KCNMB4,GP1BB,FAM19A2,FAM107A,HAS2,INSM1,LSAMP,MEIS1,MEIS2,TAGLN3,NPTX1,NRCAM,NTRK2,PCDH8,PRTG,EPB41L4B,CEP41,DIRAS2,PTX3,NKAIN1,CEP97,CCDC40,GAL3ST4,ZMAT4,FIGN,C12orf49,RPS6KA2,HUNK,SALL1,MAPK12,CSRNP3,ZNF821,ANKRD6,SLC4A3,SLC9A5,ZNF334,CLSTN2,TAL1,CUX2,ASXL3,TP53BP1,TPM2,CA14,ZNF24,ZNF184,PCBP4,NETO2" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k3_500 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.04E-09 1.48E-05 3.25E-08 2.94E-07 43 161 "PKP4,DOCK11,BACH1,RUNX1T1,SRSF11,SLIT2,COL4A5,RBM39,TCAF1,AIF1L,ZC3H11A,EDNRA,EIF4G1,EMX2,EPB41L2,SMC2,APOPT1,TUBGCP4,SRCAP,LPAR4,CHIC1,MEIS1,MEIS2,MMP16,MSI1,CNOT4,KANSL1,TMEM255A,C1orf54,PBRM1,TMLHE,TRA2B,CHD9,SLC12A2,ZC3H13,TROVE2,CBX5,SSBP2,FLRT2,PCDH20,ZNF711,ADAMTS9,GAN" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_1000 kidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.53E-09 1.72E-05 3.76E-08 3.41E-07 142 850 "RALGAPA1,NDRG2,FMNL2,USP31,MTUS1,HECW2,ADGRF5,SPARCL1,SEMA6A,AMPD3,SEMA7A,C6orf89,MAP4K3,APBB2,ARNTL,ATP1B3,ADAM15,NRP2,GPR146,CFLAR,PROM1,SYNJ1,MTMR2,IL33,CA8,CAST,CH25H,CBLN1,CLDN10,LDB2,CD38,CHN2,TAOK2,CLTB,ABCG2,TMEM184B,ARHGEF6,CLOCK,ANKRD44,ABCG1,SNCAIP,CSF1,CST3,PLXNA4,PPP1R16B,DOCK4,PITPNC1,ELMO1,NR1D2,ECM2,EBF1,EDN1,EDNRB,SEMA3D,KLHL5,TMTC1,MBNL2,IRAK4,CALCRL,EZH1,F8,DLC1,ST3GAL6,CHST15,FLT1,PDLIM5,TRIM16,ST6GALNAC3,GALNT15,ERAP1,INPP5K,PCDH17,GGTA1P,FERMT2,LPAR4,IRAK3,HLF,ICA1,IFI16,IGF1,SCIN,IL6ST,ITPKB,STXBP5,LIFR,LMO2,SMAD1,AQP11,TM6SF1,MEF2C,MEIS2,MYO6,NFE2L2,NFIX,PFKFB3,PLTP,PMP22,SEPT4,DRAM2,MINDY2,RASGEF1B,SNRK,PTPRB,PTPRG,RIPOR1,ZDHHC14,RDX,LRRK2,MAPK12,FNIP1,SGK1,PREX2,EPN2,LIMS2,SLC14A1,CPEB4,LIMCH1,LMBRD1,ZHX3,ARHGAP26,SPTAN1,ITPRID2,THSD1,RGL1,STXBP1,PLCB1,ANKRD28,ANKRD12,KLHL4,TCF4,SYNE1,DOCK9,TNS2,TEK,C18orf54,SLC44A1,TLR4,TNS1,UCHL1,AGMO,ZBTB38,PLSCR4" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500 FaceBase_RNAseq 3.58E-09 1.74E-05 3.80E-08 3.44E-07 93 489 "EMILIN3,NDRG2,SRPX,ARHGAP20,LTBP4,GPRASP2,CDK10,ADGRB2,CACNA1G,LDLRAD4,CA4,CACNA2D1,LONRF2,KCNAB3,CDO1,CRLF1,LHX2,ABI3BP,IGDCC3,HAPLN1,ANKRD44,CSF1R,SPOCK2,RUSC2,DMD,SHANK1,DTNA,MAMLD1,SEMA3D,EGFR,RASA4,ELN,TMEM35A,LRRC17,APC2,CHST15,FCGRT,FGF11,TRIM16,TPPP3,FYB1,TMEM8B,PCDH17,PPARGC1A,ZNF276,GSN,SYNPO,NEGR1,ZIC5,MEIS2,SRSF12,NEXMIF,TCEAL5,NCAM2,NELL2,NFIX,NNAT,CNTN3,PCDH9,PRTG,SEMA5B,TMEM38A,PLCL1,FXYD1,POU6F1,IRX1,PRKAR1B,PRODH,ACSS3,ZMAT4,ZFHX4,EMID1,STX1B,DGLUCY,SALL1,SH3GL3,FERMT1,NLGN1,CLSTN2,RHBDL3,ADAMTS17,PLCB1,ADGRL3,CUX2,PHF24,FAM189A1,KCNE5,TSPAN11,ZIC1,ZIC2,CADM2,NAV3,SENP7" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.82E-09 1.86E-05 4.05E-08 3.67E-07 137 813 "AXIN2,PCDH19,SEMA6A,CEP126,SYT13,DOC2A,FGD2,EPB41L5,CDC14B,PDE8B,ZNF599,PROM1,BMP7,BMPR1B,CA12,CACNA1B,CALB1,MTMR7,LRBA,MAGI1,CRLF1,CBARP,B4GALT6,SLIT2,PICK1,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,FAM169A,KIAA0040,CTH,GREB1,RIMS2,KATNAL2,AIF1L,MFAP3L,CHRDL1,RAB39B,DUSP9,EEF1D,TENM1,PLEKHA1,EMX2,ENO2,ACSL4,SPSB4,FGF12,SEMA4D,SPECC1,USP21,RASL10A,PRELID3A,GALC,MTHFD2,PPARGC1A,TOX3,MAP7D2,GRIK4,FAM19A2,RABL2A,PADI2,FRMD5,SCIN,SLC35G1,KCNJ16,KIT,L1CAM,GPR155,AQP11,MBP,KITLG,PTOV1,MYCN,LYRM9,VWA2,NPTX1,NRCAM,CNTN3,CDK18,PRTG,PFKFB3,SEMA5B,PKM,KCTD15,PLCL1,SLC25A23,PLXNB1,MAPK4,GDPD1,LAMA1,EML5,NKAIN1,CEP97,CCDC40,FAM184A,SUSD4,RASGRF2,GAL3ST4,RET,NUDT11,C12orf49,SGSM1,EMID1,SCN2B,SCN8A,SHMT2,HKDC1,FHOD3,ST6GAL1,KBTBD4,INAVA,SOX11,NUDT10,TMEM150C,WSCD1,CUX2,DCBLD1,CA14,RPRM,UCHL1,UGT8,LMF1,VSNL1,EMX2OS,ZNF142,FSTL5,ZNF184,DPYSL5,TMEM178A,CIAPIN1,SEMA3B,FZD3,DOCK8,PHTF2,AAAS,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K1 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 4.48E-09 2.17E-05 4.74E-08 4.29E-07 26 72 "PLEKHH1,EPB41L5,PROM1,LHX2,IGDCC3,FAM169A,EMX2,EPB41,RRAGB,ACSL4,KHDRBS3,FUT9,KIAA1841,TOX3,PCLO,SOX21,KTN1,PAX6,NECAB2,ELOVL2,EML5,MAPK12,KIF21A,SP4,WSCD1,NR2E1" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k2_1000 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.57E-09 2.22E-05 4.82E-08 4.37E-07 43 163 "ADCY6,ESYT2,ATP2A2,SGCE,CACNA2D1,ARHGEF6,HDAC9,MYADM,ARHGAP24,DGKB,EBF1,FRY,RCAN2,LRRC17,RASGRP2,MRVI1,DLC1,ST3GAL6,IQGAP2,GNAO1,FERMT2,GUCY1A1,GUCY1B1,IL6ST,HECTD2,GPR155,MARK1,ADAM22,NCF2,PDE3A,SERPINI1,PLCL1,SEPT4,PKIA,ZDHHC14,FAM81A,SLC8A1,SLC12A2,CPEB4,TNS1,TPM1,PHTF2,MSRB3" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_500 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.99E-09 2.42E-05 5.26E-08 4.77E-07 83 422 "FMNL2,AXIN2,MTA3,KLHL13,ARHGAP20,OGT,SEMA7A,APOC1,LGR5,CDC14B,SEMA4G,PPP4R4,PDE8B,INSYN2B,RNF182,BCHE,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,BOC,DOCK4,DAPK1,DOCK2,DRP2,RASGRP1,OPTN,MRO,EMX2,NRN1,AFF2,NSG1,ZMAT1,GALC,GATM,SESN1,TCEAL6,SHISA6,FAM69A,SLC35G1,KCND2,KLHL23,MAP2,KITLG,LAYN,MYO9A,NEXMIF,NPR2,ENPP2,SERPINI1,PCDH18,MAPK9,GDPD1,GDPD2,CNTLN,RNASEL,ZFHX4,MEG3,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,SLC4A3,KDM3A,UHRF1BP1L,ARHGAP26,TSPYL2,ST5,ADAMTS17,ADGRL3,TCF12,ACTR6,DCBLD1,TST,VSNL1,ZNF23,ELFN1,LYPD6,TMEM178A,WNK3,FRMD6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.04E-09 2.45E-05 5.30E-08 4.80E-07 22 54 "ANK2,VAT1L,CADPS,NRP2,DCLK1,RAB33A,PLXNA4,SCRN1,EYA1,TUBB3,IGSF5,GFRA2,GNAO1,STMN2,L1CAM,SYTL4,NEFM,TMOD2,MAPK10,EML5,RTN1,SNAP25" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500_k4 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.12E-09 2.49E-05 5.37E-08 4.87E-07 41 152 "PKP4,BACH1,SGCE,IL33,RUNX1T1,ZNF445,SRSF11,SLIT2,COL4A5,AIF1L,ZC3H11A,CDON,EIF4G1,EPB41L2,ANKFY1,SMC2,LPAR4,RASSF8,HAS2,MAP4,CHIC1,MEIS1,MEIS2,SAMD5,PCDH9,PIK3R1,TMEM255A,C1orf54,RNASEL,MEG3,TRA2B,CHD9,TET1,PRRC2C,SYNE2,CBX5,TRPS1,SSBP2,UBE3A,FLRT2,VLDLR" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500 DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.26E-09 2.55E-05 5.50E-08 4.99E-07 78 388 "TMCC3,ADD1,ADORA1,LCORL,PKP4,LGR5,PDE8B,INSYN2B,BACH1,SYNJ1,ARHGEF7,JAZF1,SRSF11,CNR1,COL4A5,ABI3BP,RBM39,DZIP3,GREB1,PUM1,DOCK4,ZC3H11A,GSDME,DYNC1I1,EDNRA,RASGRP1,PLXNC1,EIF4G1,CALCRL,EMX2,EPB41L2,NRN1,SCML2,MEX3B,GATM,AIFM3,MAP7D2,LPAR4,SHISA6,KCND2,KIT,CHIC1,KITLG,MMP16,NEXMIF,CNOT4,GLIPR1L2,PDPK1,ABCB1,SERPINI1,MAPK10,GDPD1,RNASEL,TMLHE,MEG3,PRCD,FNIP1,TNFRSF19,ARX,CPEB3,SYBU,SLC12A2,CPEB4,ZC3H13,RBM26,LARP4,SYNE2,ANKRD12,DMXL2,CBX5,R3HDM1,RASD2,SSBP2,ZNF711,ZNF23,NDRG4,ADAMTS9,GAN" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1 gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1 Gudmap RNAseq 5.36E-09 2.60E-05 5.60E-08 5.08E-07 161 1002 "ABR,AXIN2,PCDH19,AK2,DOC2A,AMPH,VAT1L,CPNE5,LGR5,CDC14B,TMEFF1,ARHGDIG,MARCH3,DYNLL1,BACH1,PROM1,BMP7,BMPR1B,WASF1,MYRF,CA4,ARHGEF2,CRLF1,B4GALT6,SLIT2,PPT2,MYL6B,HOMER3,CNTFR,SLC4A8,ZNF385A,CRMP1,HAPLN1,HINFP,IPCEF1,SIPA1L1,PLXNA4,FAM169A,CTH,GREB1,CYBB,KATNAL2,TMEM170A,AIF1L,CASP8AP2,DPYSL2,ARRDC4,DTNA,DUSP9,E2F5,SEZ6L2,SEMA3D,RASA4,EIF1,EYA1,CD320,SPSB4,FGF12,ZMYND15,SEMA4D,HVCN1,UFM1,RASL10A,NFU1,GFER,TOX3,KDM2B,POLL,STMN2,CACFD1,RNF165,LINGO1,FAM107A,MUM1,HAS2,PADI2,HLF,ACOT7,LRRC75A,SHISAL1,IBA57,METTL21A,KCNH2,KCNJ16,GATD1,KIT,L1CAM,STMN1,LYPLAL1,MATK,AQP11,ADAM11,MOV10,BLOC1S2,MYCN,NEFM,PDE4A,PDE1B,PKM,SMOX,PRIMPOL,POLR2F,FSD1,PPP1R1A,PPP5C,CEP41,MAPK4,MASP1,LAMA1,ELOVL2,SPDL1,EML5,PTPRG,NKAIN1,TMEM231,CCDC40,ROGDI,NUDT11,ROBO2,PCMTD2,RPS6KA2,RTN1,TRAPPC13,SCN2B,SCN8A,HES6,ZNF821,COPZ1,SH3GL3,FHOD3,ST6GAL1,SLC4A3,CXXC4,SNAP25,SOX11,SST,ZC4H2,STX1A,KANK1,SYT5,MTCL1,TBCEL,WSCD1,CUX2,ZFPM2,ARL10,DCBLD1,TSN,HSPBP1,CCDC136,VLDLR,SPHK2,ANKS1B,SLC38A1,CIAPIN1,PPP1R3F,PLD4,FZD3,MARCH8,AP3B2,SPATA13" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.87E-09 2.85E-05 6.11E-08 5.54E-07 48 194 "EMILIN3,USP31,TAOK1,APAF1,APC,PHYHD1,LGR5,CASK,BCHE,BMP7,CACNA2D1,VCAN,MFAP3L,DPYSL2,EDNRA,EDNRB,HIPK3,SEMA3D,ETV1,DLC1,CELF1,IQGAP2,PCDH17,GHR,PPARGC1A,FERMT2,GRIA2,GUCY1B1,ZDHHC15,KITLG,PPM1L,MKLN1,PDE3A,PIK3C2A,KANSL1,REV3L,SETD5,TNFRSF19,ZHX3,NEK4,FBXW11,TBL1X,NSD1,ERCC6L2,RGMB,TRIO,TRPS1,MSRB3" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_500 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.97E-09 2.90E-05 6.21E-08 5.63E-07 40 147 "ADORA1,AMH,SEMA7A,ARHGDIG,CADPS,BCHE,SYNJ2,CACNA2D2,CLTB,COL9A3,MAGED1,CST3,PPP1R16B,JAKMIP2,PLPPR4,RCAN1,DTNA,MRO,PLXNC1,CERCAM,ERBB4,REEP2,PTK2B,TUBB3,FGF13,CSPG5,GATM,PADI2,MYO7A,PGAM2,SCHIP1,RASGEF1B,MASP1,DUSP15,SLC6A8,TACC1,SIN3B,THRA,TIAM1,SGK3" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_500 DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.10E-09 2.96E-05 6.32E-08 5.73E-07 80 403 "ADD1,SEMA7A,LCORL,PKP4,LGR5,RNF182,BACH1,RUNX1T1,CBLN1,ZNF445,SRSF11,CHGB,QKI,COL9A3,RBM39,FAM169A,DZIP3,PUM1,AIF1L,ZC3H11A,GSDME,DTNA,EDNRA,PLXNC1,EIF4G1,EPB41L2,SRRM1,FAM198B,PTK2B,SCML2,CHST15,MEX3B,SMC2,FYN,GATM,CSDC2,LPAR4,GPR37,FAM19A2,MAP4,CHIC1,MEIS1,MEIS2,KITLG,MID1,MSI1,NEFM,PCSK5,PLTP,DIRAS2,TMEM255A,TMLHE,ROBO2,MEG3,ATXN2,TRA2B,ARX,SLC12A2,TET1,ZKSCAN3,SMARCA4,SP4,ZC3H13,RBM26,RGL1,PRRC2C,SYNE2,KLHL4,OBSL1,CBX5,ASXL3,R3HDM1,TPM1,NR2C2,SSBP2,UBTF,FLRT2,STOX2,ADAMTS9,GAN" Coexpression Atlas GSM605853_500 "Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3" "Immgen.org, GSE15907" 6.10E-09 2.96E-05 6.32E-08 5.73E-07 80 403 "FMNL2,TMCC3,ADRB2,SEMA6A,ABCD2,FGD2,ASPA,ATP6V0A1,ADAM23,DST,HAP1,CD86,SCARB1,CD38,DGKI,LARGE1,MS4A7,LY86,CSF1R,CYBB,DOCK4,HDAC9,ARHGAP32,GSDME,DMPK,HS3ST2,ABCC5,PCOLCE2,SLC43A2,IGSF6,TLR7,SIRPB1,RPS6KC1,DLC1,FCGR1A,FCGR3A,FCGRT,FER,PCYOX1,TMEM107,MPP6,GALC,GATM,GFRA2,HPGDS,GLUL,IGF1,LRRC25,KCNJ16,TTYH2,SCAMP5,MITF,ADAM22,MYO9A,P2RY13,ENPP2,PLCL1,PILRA,DRAM2,RASGEF1B,GDPD1,PTK2,PID1,RXRA,SEMA6D,SLC8A1,CCDC88A,SLC11A1,SLC12A2,RGL1,SYNE2,SLC37A2,ADGRL3,DMXL2,TPCN2,TLR4,TNS1,TRPM2,AGMO,PLD4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.12E-09 2.97E-05 6.32E-08 5.73E-07 74 362 "NDRG2,ALCAM,ARHGAP20,LTBP4,TMEM108,CACNA1G,MYRF,CACNA2D1,RUNX1T1,ARHGEF25,CBLN1,LDB2,SLIT2,CNTFR,AKAP5,CLIP3,SNCAIP,VCAN,PLXNA4,RIPOR2,ARHGAP24,ARMCX2,DNM1,EDNRA,HEYL,EGFR,PLXNC1,LRRC17,EYA1,NRN1,FAM198B,DLC1,FLNC,AFF2,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,GUCY1A1,GUCY1B1,IGF1,KCND2,LAMA2,MAP2,MATN2,MEIS1,NEXMIF,PCDH9,FXYD1,PCDH18,PLTP,PMP22,SH3KBP1,LRRN3,MASP1,LAMA1,PTCH1,PTN,TMEM255A,ROBO2,MEG3,PKNOX2,SULF2,ADGRL3,ZFPM2,TPM1,SSBP2,PLEKHH2,VSNL1,STOX2,WNK3,ST8SIA2" Coexpression Atlas Arv_SC-HD_1000_K1 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 6.31E-09 3.06E-05 6.50E-08 5.89E-07 102 559 "SYN3,TMEM132B,GALNT13,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,KIF1A,ADGRB1,HAP1,CLDN10,CCK,SYNGR3,FAM19A5,CCDC151,IGLON5,CABP1,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,SEC14L5,KCTD8,BRINP1,DPP6,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,IGSF5,GNG4,LPAR4,LINGO1,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KCNN1,KIF5A,CAMK2N2,CHST6,TCEAL5,FXYD7,NELL2,NNAT,SEMA5B,JAKMIP1,NECAB2,MAGEL2,PPP2R2B,LAMA1,GDPD2,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,HUNK,SALL1,TMEM200C,PPM1E,SOX3,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,CA14,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,DPYSL5,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_500 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.32E-09 3.07E-05 6.50E-08 5.89E-07 86 445 "KLHL32,OSBPL8,C1QTNF1,EPB41L5,APLP1,UPRT,ASPA,TMEM108,CFLAR,DST,CA12,THSD7A,LRBA,LRRFIP1,CLTB,CLOCK,SNCAIP,DOCK4,ARHGAP32,ARHGAP24,AIF1L,ELMO1,TSPAN5,TMTC1,OPTN,CEP85L,TLR7,ACSL4,CORO2B,ST3GAL6,UFM1,PDLIM5,ST6GALNAC3,GALC,IQGAP2,ERAP1,MALT1,FERMT2,TDRKH,PARD3B,RASSF8,UBE2QL1,NXPH3,SYNPO,IL6ST,MAPT,AFF1,LYRM9,MYO6,NEK1,NELL2,NTRK3,PDE4B,PDE4D,CCSER2,RETREG1,PLCL1,SCHIP1,FA2H,MINDY2,PKIA,PTH1R,PTPRO,RIPOR1,FAM184A,ZDHHC14,ROBO2,ST6GALNAC6,GALNT10,ST6GAL1,ABLIM3,SLA,FAM81A,CPEB4,LMBRD1,DDN,NXT2,KANK1,VPS13A,TMEM150C,ASTN2,TNS2,FRYL,SGK3,FLRT2,PLEKHH2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_1000_J DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.41E-09 3.11E-05 6.57E-08 5.96E-07 131 774 "NDRG2,ADCY5,PLEKHH1,USP31,ADGRF5,SPARCL1,PI16,APC,VAT1L,ATP2A2,ATP6V0A1,MYOM1,ADAM23,NRP2,DST,CACNA1B,CACNA2D1,CACNB4,CAST,ENTPD2,LRRFIP1,CFL2,CHGB,CLCN3,CNR1,CNTN1,AKAP5,ABI3BP,GDA,OSBPL3,CNTNAP2,KIAA0040,MYADM,MFAP3L,TMEM130,SPOCK3,CHRDL1,DMPK,CPEB2,DTNA,ABCC5,HIPK3,ELN,CALCRL,MRVI1,NRN1,ACSL4,TUBB3,DLC1,PRKAG2,FHL1,FOXF2,FLNC,PDLIM5,TRIM16,FUT9,SDCBP2,CHL1,GALNT15,IGSF5,GCNT2,LYVE1,GNG4,FERMT2,PRUNE2,STMN2,TPPP,GSN,BVES,IFI16,IL6ST,SLC35G1,KIF5A,MAP4,MBP,MYH3,NEFM,NFE2L2,NPTX2,PDE4B,PDE4D,PIK3C2A,SCHIP1,FA2H,KANSL1,PRKCB,MAPK10,PRPH,RET,REV3L,RGS4,ZFHX4,RTN1,RYR3,SCN7A,STUM,SH3BGR,FHOD3,LIMS2,SLC14A1,SNAP25,FNBP1,ZHX3,MYCBP2,DBNDD2,ATP10B,CLASP2,SYN2,COBL,TACC1,PCDHB7,ZNF106,SLC44A1,ENHO,TLR4,ERCC6L2,TNS1,RASD2,TPM1,TPM2,SYNPO2,PPIL6,UCHL1,TBC1D15,RBFOX3,AGMO,FSTL5,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.87E-09 3.33E-05 7.03E-08 6.38E-07 98 531 "ABHD6,METAP1D,ADCY8,SLC24A4,KIAA1324,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,SPTBN4,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,GPC2,LDLRAD4,KCNAB3,CDO1,CCPG1,UBE2L6,VAX2,CRYBB1,CLIP3,CSF1R,SUSD5,DGKG,TIAM2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,PTK2B,FCGRT,DLL3,STAU2,ABLIM2,FYB1,ZMAT1,GAA,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,ICA1,SCIN,KLHL23,CREG2,GPR155,MID1,MITF,N6AMT1,MYH3,TCEAL5,NPY,NPR2,CNTN3,PDE4D,PLCL1,TRHDE,SDK2,PILRA,PRKAR1B,DIRAS2,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,DUSP15,MORC4,PRIMA1,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,ASAP3,CCDC92,SMARCC2,ARHGAP26,IQSEC2,NKAIN2,ADGRL3,PHF24,FAM189A1,LRRC24,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.98E-09 3.39E-05 7.14E-08 6.47E-07 57 251 "METAP1D,FMNL2,AXIN2,KLHL13,LRCH2,LCORL,PPP4R4,IGDCC4,PDE8B,NUMB,INSYN2B,WASF1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,EMX2,MTSS1L,NRN1,OLFM1,NEU3,IGF1,KLHL23,KITLG,NELL2,NPR2,NUCB2,SERPINI1,GDPD2,CNTLN,FAT4,ZFHX4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ZFP30,SLC4A3,KDM3A,UHRF1BP1L,LHPP,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,CCDC173,ACTR6,LYPD6,FRMD6,DPF3" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.04E-09 3.42E-05 7.18E-08 6.51E-07 84 432 "KDM5D,FMNL2,HECW2,SEMA7A,GAS7,LGR5,PPP4R4,CADPS,NUMB,ALDH7A1,DST,ST3GAL5,CALB1,RGN,SLC16A4,DCLK1,MAGI1,CDO1,QKI,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,CDON,DRP2,DTNB,RASGRP1,MRO,PLXNC1,TMEM35A,EMX2,MTSS1L,NRN1,FAM198B,PTK2B,CAMKK2,GATM,PPARGC1A,GPR37,PACSIN2,KLHL23,MATN2,KITLG,AFF1,MSI1,MYO9A,NUCB2,ABCB1,SERPINI1,PIK3C2A,PPP3CC,RASGEF1B,PRKCB,RBBP8,REV3L,RNASE1,ZFHX4,ROBO1,RPS6KA2,HUNK,TNFRSF19,MRAS,ST6GAL1,ST8SIA1,SLC4A3,SNCA,UHRF1BP1L,SPP1,ST5,ADGRL3,OBSL1,DNAH7,ZFPM2,HEY1,ACTR6,TST,PCDH20,ZNF23,SPIRE1,SLC38A1,ADAMTS9,WNK3,DPF3" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.25E-09 3.52E-05 7.38E-08 6.69E-07 140 844 "DGCR6,ABCF1,KDM5D,ADD1,AK2,OGT,LCORL,EPB41L5,APLP1,CASK,TMEM108,BACH1,MYRF,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,ARHGEF2,LHX2,COL9A1,RBM39,CRMP1,HAPLN1,RNF14,CLIP3,CSNK1E,PUM1,ARHGAP32,TCAF1,DAPK1,SCRN1,DAPK3,DBI,DBN1,DCTN1,GSDME,SACS,RCAN1,DNM1L,EDNRA,MBNL2,EIF4G1,EPB41L2,TUBB3,SEC24B,FER,FGFR1,MEX3B,SYNCRIP,PDLIM5,STAMBP,DLL3,TCERG1,TOX3,KIAA1958,LPAR4,STMN2,GRB10,BACH2,SMAP1,NKD1,INSM1,KIF2A,SMAD1,MAPT,CHIC1,MEF2C,TAGLN3,NEFM,NFYA,NNAT,GPR85,GNG2,OLA1,PIK3R1,PKM,PCDH18,EXOSC10,SH3KBP1,PPP2R5E,PRKACB,ZIK1,PTPRG,NKAIN1,GAL3ST4,UBR7,ZFHX4,MEG3,ATAT1,ZNF354C,ATXN2,SEC14L1,SUPT20H,ARX,SHMT2,ST6GAL1,WDR37,ZKSCAN3,SMARCA4,SNAP25,SNRPN,SOX11,RBM26,SPART,TROVE2,SULF2,JMJD6,PJA1,FBXW11,KLHL4,TRIM2,TCF12,USP22,CLASP1,PUM2,TMEM9,ASXL3,TMPO,TNS1,STXBP4,TSC2,SSBP2,TST,UBTF,UCHL1,USP1,ZFP37,ZIC1,ZFAND5,MEIS3,INTS3,STOX2,CIAPIN1,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas Arv_SC-HD_2500_K2 AravindRamakr_StemCell-HD_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 7.69E-09 3.74E-05 7.82E-08 7.09E-07 176 1125 "KCNH8,SYN3,TMEM132B,ADCY8,GALNT13,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,TMEM108,KIF1A,CARMIL3,ADGRB1,CACNA1G,HAP1,CLDN10,MTMR7,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,FAM19A5,SULT4A1,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,KATNAL2,KIF26A,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,PARD6A,CHRDL1,DPP6,SEZ6L2,AASS,PIPOX,ADGRV1,PPP1R1B,ZNF589,OLFM1,FGFR1,HPCAL4,FLT1,SYT3,CSPG5,TVP23A,MEGF11,MEGF10,HRASLS5,GABRA3,GABRB3,SRRM4,IGSF5,GCK,GDF1,TTBK1,KDM2B,GNAL,GNG4,LPAR4,GRIK5,GRIN2D,LINGO1,PSIP1,PADI2,ARHGAP36,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KIF5A,CAMK2N2,CHST6,MMP17,MPP2,ADAM22,MYCN,TCEAL5,FXYD7,NEFM,NELL2,NNAT,PCBP3,NLGN3,SEMA5B,JAKMIP1,PURG,PSAT1,NECAB2,MAGEL2,PPP2R2B,PPP2R2C,NKAIN4,LAMA1,GDPD2,PTPRD,PTPRN,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,RET,PTGR2,HUNK,SALL1,TMEM200C,PPM1E,CNKSR2,PREX2,SEPHS1,TET1,MAST1,SOX3,NMNAT2,HECW1,SOX21-AS1,SEPT3,RHBDL3,NUDT10,ARC,SYP,SYT1,COBL,KLHL4,FAM189A1,SLC19A3,PCDHA3,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,KCNE5,CA14,CLEC2L,UGT8,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,DPYSL5,CADM2,GAL3ST3,RGS7BP,TMEM63C,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas Arv_SC-LF_1000_K3 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 7.91E-09 3.84E-05 8.02E-08 7.27E-07 118 679 "KCNH8,SYN3,TMEM132B,ADCY8,GALNT13,UNC5A,SEMA6A,PDZD4,DPP10,PPP4R4,RASL11B,KIF1A,CARMIL3,CLDN10,SYNGR3,DLGAP1,PLEKHB1,FAM189A2,FAM19A5,CCDC151,IGLON5,PCYT1B,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,ERC2,KATNAL2,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,DPP6,SLC25A18,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SPSB4,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,GNG4,LPAR4,LINGO1,RNFT2,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KCNN1,KCNN2,KIF5A,CAMK2N2,TCEAL5,FXYD7,NELL2,NNAT,SEMA5B,JAKMIP1,MAGEL2,EPB41L4B,PPP2R2B,NKAIN4,LAMA1,GDPD2,TMEM145,NKAIN1,KHDRBS2,ZMAT4,MRAP2,SALL1,TMEM200C,SH3GL3,PREX2,SEPHS1,TET1,SNRPN,SOX3,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,SLC19A3,CCDC173,RNF175,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,CA14,RPRM,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas GSM791102_500 "Stem Cells, SC.LT34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34-, Bone marrow, avg-3" "Immgen.org, GSE15907" 8.85E-09 4.30E-05 8.95E-08 8.11E-07 74 365 "FMNL2,ZNF608,OSBPL1A,CDC42BPA,ALDH7A1,DST,BTK,SGCE,UBE2L6,B4GALT6,ABCG2,MAGED1,ZNF521,GDA,GPRASP1,ARHGAP32,DGKG,ARRDC4,EBF1,PLXNC1,CALCRL,RRAGB,EYA1,ARMCX1,MED12L,FOXO3,NBEA,GATM,GCNT2,GLUL,GRB10,PRDM5,GSTM5,GUCY1A1,IRAK3,HLF,HNMT,ICA1,KLHL23,KHK,KIT,STMN1,LMO2,LYPLAL1,MEF2C,MEIS1,MYCN,NPR2,OCRL,SNX10,PSAT1,PRODH,DEF8,RNASEL,ZNF532,PLPPR3,CCDC112,PEAR1,TET1,CABCOCO1,TROVE2,ANKRD28,KLHL4,TEK,CBX5,TLR4,TNS1,NPL,STXBP4,SSBP2,VIPR2,VLDLR,ZBTB38,PLSCR4" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000_k5 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.88E-09 4.31E-05 8.96E-08 8.13E-07 52 221 "INTS2,LCORL,LGR5,PDE8B,ASPA,INSYN2B,RNF182,SYNJ1,ARHGEF7,CALB1,LONRF2,CNR1,GREB1,DOCK4,SACS,DYNC1I1,DOCK2,DRP2,DTNB,RASGRP1,EMX2,ATP6V1H,ZMAT1,KCND2,KITLG,MYO5A,MYO9A,NEXMIF,GLIPR1L2,PDPK1,SERPINI1,TMIE,JAKMIP1,SEMA6D,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,SNCA,ARHGAP26,SLC37A2,CCDC173,DNAH7,ACTR6,ZNF711,ZNF23,EMX2OS,REEP1,TMEM178A,PHTF2,KLHDC1" Coexpression Atlas PCBC_ECTO_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 9.03E-09 4.38E-05 9.09E-08 8.24E-07 158 986 "KCNH8,AXIN2,ADORA1,DPP10,APLP1,VAT1L,LGR5,LINC00173,RASL11B,KIF1A,BMP7,CA4,CABP7,CAMK2A,ISPD,CLDN10,CCK,SYNGR3,NOG,ABCG2,FAM19A5,IGLON5,CNTFR,COL9A1,COL9A3,COL11A2,GAL3ST1,TOGARAM2,NRG2,IGDCC3,FAM171B,HAPLN1,LRRC3B,CNTNAP2,PLCXD3,GREB1,BOC,DGKG,TMEM130,LYPD1,SNAP91,KIF19,GRIN3A,DNAH9,CDON,DPP6,EMX2,ADGRV1,CLVS1,TMEM132C,SPSB4,ATP13A4,TVP23A,CHL1,SYT17,AIFM3,PRUNE2,LPAR4,GRM2,GUCY1B1,UBE2QL1,IGFBPL1,C9orf129,SHISA6,CELF5,IRF8,SLC6A17,INSM1,LRRTM1,ITGA7,ITPKB,KCND1,KCND2,KCNN3,CLEC18A,MAP2,MAP6,SAMD5,MYO7A,TCEAL5,NELL2,NNAT,NPY,NTRK3,IGSF11,CNTN3,PAX6,PRTG,PDE1B,ENPP2,SDK2,NECAB2,FA2H,NKAIN4,VSTM2L,RELN,KLK6,LAMA1,GDPD2,STK32A,PTPRD,STRC,TMEM255A,KHDRBS2,PRRT2,ZFHX4,KLHDC8A,MELTF-AS1,HUNK,KCNIP1,LRFN5,TMEM200C,ARX,PKNOX2,DMRTC1,CABCOCO1,SOX3,SOX15,NMNAT2,SPTB,LMO3,CLSTN2,SST,SOX21-AS1,PCDHGB6,PCDHB15,PCDHA6,PCDHA3,PCDHA2,RNF175,DICER1-AS1,ICAM5,NR2E1,RIMBP2,DOK6,PPIL6,CA14,CLEC2L,ZNF709,VGF,TSPAN11,RBFOX3,ZIC1,ZIC2,KCNT2,EMX2OS,CRB2,DPYSL5,ANKS1B,LAMP5,CADM2,GAL3ST3,DNAH10,DOCK8,FAM182B,ADAMTSL3,FAM181A,JPH3" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.09E-09 4.41E-05 9.14E-08 8.28E-07 33 110 "CADPS,ADGRB3,DCLK1,CRMP1,CSNK1E,KIAA0408,TCAF1,JAKMIP2,GSDME,EDNRB,TUBB3,DLL3,MEGF10,TOX3,STMN2,RNF165,HMGCR,INSM1,TAGLN3,NEFM,PCDH8,SLC10A4,GNG2,MAPK10,FIGN,RGS4,ZFHX4,SNAP25,TROVE2,CLASP1,ZIC1,ZNF24,PCBP4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.66E-09 4.69E-05 9.69E-08 8.78E-07 59 266 "SPARCL1,ALCAM,ARHGAP20,LTBP4,SLC4A4,SGCE,CACNA1G,MYRF,CACNA2D1,ARHGEF25,LDB2,SLIT2,CNTFR,ZNF521,VCAN,BOC,ARMCX2,DNM1,EDNRA,SEMA3D,EGFR,LRRC17,FLNC,GFRA2,FREM1,CSDC2,GHR,GLI2,GUCY1A1,GUCY1B1,TCEAL6,LAMP2,MEIS1,NFIX,NNAT,NME4,PCDH9,PDE3A,PIK3R1,FXYD1,PCDH18,PRKACB,LAMA1,PTN,TMEM255A,MEG3,ZNF354C,SATB1,DZIP1,PKNOX2,PEG10,SULF2,ASXL3,TPM1,TRPS1,FLRT2,PLEKHH2,VSNL1,ZNF711" Coexpression Atlas geo_heart_1000_K5 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 9.81E-09 4.76E-05 9.82E-08 8.90E-07 83 428 "ADCY5,DPY19L2P4,AGT,CARNS1,MYH7B,DDO,CPNE5,SPTBN4,ATP1A3,MYOM1,RGS11,LDHD,CA4,CAMK2A,CAMK2B,USP2,ENTPD2,LONRF2,MS4A7,AKAP6,NRG2,CSF1R,PDE4DIP,PLCXD3,DMPK,ECM2,HEYL,SRPK3,ELN,RCAN2,TMEM132C,FGF12,FLNC,FOLR2,ABLIM2,IP6K3,CYP46A1,GPD1,TPPP,PLPP7,LINC01550,UBE2QL1,FRMD3,HLF,SYNPO,KCNJ5,MAPT,COL28A1,NFIX,NTRK2,PDE1C,PDE3A,PGAM2,RETREG1,PLCL1,PLIN1,FXYD1,MAPK4,FITM2,MASP1,CRTAC1,GLDN,SCN2B,SCN7A,FHOD3,SLC4A3,LIMS2,SLC8A1,FAIM2,PDZD2,ADHFE1,PCDHGC5,PCDHGA6,PCDHGA2,TIMP4,TNS1,TPM1,SYNPO2,VIPR2,NDRG4,WNK2,ADAMTSL3,DPF3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.01E-08 4.92E-05 1.01E-07 9.18E-07 47 191 "FMNL2,KLHL13,PPP4R4,IGDCC4,NUMB,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,AKAP5,PLXNA4,CTH,DOCK4,DAPK1,CDON,DRP2,RASGRP1,KLHL5,EMX2,NRN1,IP6K2,TRAF3IP2,KCND2,KLHL23,MAP2,MATN2,KITLG,MYO9A,PPP3CC,PTPN13,REV3L,ZFHX4,HUNK,TNFRSF19,RASA3,ZFP30,ST8SIA1,SLC4A3,KDM3A,UHRF1BP1L,ST5,ADGRL3,ZFPM2,ACTR6,KAT6B,ZNF23" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k1 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.06E-08 5.15E-05 1.06E-07 9.58E-07 55 241 "ABR,INTS2,VAT1L,BBS2,BCHE,IL33,CACNA2D1,CH25H,ZFP28,NSL1,SNCAIP,VCAN,RIMS2,CENPL,MTX3,ARRDC4,ADGRV1,ST3GAL6,FAM49B,MEGF10,SRCAP,BRD8,TDRKH,PSIP1,NEGR1,ING3,EPDR1,PIGG,PPP2R3C,FAM184A,ENOX1,CRTAC1,RPS20,SALL1,ZFP2,SUPT20H,TRA2B,HSPA4L,PPM1E,SLC12A2,MBD5,SOX11,NEK4,ANKRD28,PCDHB9,FRYL,TPM2,RGMB,STXBP4,TSN,RPL7L1,XRCC4,ZFAND5,PHTF2,SOCS4" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000_k5 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.07E-08 5.19E-05 1.06E-07 9.65E-07 65 306 "AXIN2,SYT13,FGD2,PDE8B,PROM1,BMP7,BMPR1B,CACNA1B,CALB1,MTMR7,MAGI1,CRLF1,CBARP,B4GALT6,SLIT2,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,FAM169A,RIMS2,AIF1L,DUSP9,EMX2,ACSL4,SPSB4,FGF12,SEMA4D,RASL10A,TOX3,MAP7D2,PADI2,FRMD5,L1CAM,MBP,KITLG,LYRM9,VWA2,NRCAM,CDK18,SEMA5B,PLCL1,SLC25A23,GDPD1,LAMA1,EML5,FAM184A,SUSD4,RASGRF2,RET,SGSM1,SCN2B,FHOD3,INAVA,NUDT10,TMEM150C,WSCD1,DCBLD1,RPRM,UCHL1,LMF1,VSNL1,FSTL5,DPYSL5,DOCK8" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k1_1000 kidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.08E-08 5.23E-05 1.07E-07 9.69E-07 79 401 "ABR,RNF157,ZNF608,CEP126,AMPH,SEMA4G,BCL7A,BMP7,CACNB4,LONRF2,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,GSDME,SNAP91,MTX3,DTNA,C8orf37,ERBB2,ETV1,RRAGB,EYA1,SLC9B2,FGFR1,MAD2L2,SCARA3,NOP56,TMEM107,STAU2,IGSF5,FREM1,TDRKH,CNTRL,GRIK4,CACFD1,FAM107A,HAS2,NEGR1,MEST,MSI1,ADAM22,NME4,CNTN3,PRTG,SMOX,ANKRD16,CEP41,MASP1,RBBP6,TSPY26P,NUDT11,HUNK,ZNF354C,SALL1,PPM1E,DZIP1,SLC4A3,SEPHS1,GKAP1,CMTR2,NUDT10,ADAMTS17,CAMTA1,CUX2,TRIM2,PCDHB10,PCDHB9,PCDHB7,PCDHB3,MKRN3,LAMP5,SLC38A1,SIGLEC10,FZD3,DPF3" Coexpression Atlas PCBC_ratio_EB_vs_SC_1000 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000 PCBC 1.13E-08 5.48E-05 1.12E-07 1.01E-06 159 997 "NCKAP5,ADRA1B,PCDH19,AGT,KCTD16,SORCS2,SPARCL1,PCDH10,LGR5,INSYN2B,TTLL9,MYRF,LDLRAD4,CABP7,THSD7A,CAMK2A,NOG,SLIT2,LHX2,CNR1,CNTFR,AKAP6,ABI3BP,CRHBP,HAPLN1,PHACTR3,PYGO1,ARHGAP24,ZNF804A,LYPD1,DLX1,DUSP9,EBF1,EDN1,EDN3,EDNRA,MBNL2,CERCAM,EMX2,ERBB4,NCALD,NRN1,CLVS1,FAM198B,TMEM132C,DLC1,ZMYND10,FOXF2,FLNC,PSD2,TPPP3,CPLX2,FREM1,PCDH17,GGT5,GHR,DCLK2,GP1BB,CCDC184,GPER1,STMN2,GRIA2,C1QL4,GUCY1A1,ATOH8,UBE2QL1,FRMD3,SYNPO,C2orf72,IGF1,NKD1,KIAA1755,IL6ST,INSM1,LRRTM1,NME9,CDH20,KCNK3,LMO2,SYTL4,SMAD9,GPR155,CLEC18A,MAP6,MAPT,LRP1B,MEIS1,MEIS2,SAMD5,TAGLN3,RTL5,MYT1,NFIX,NTRK2,PAX6,PDE1C,GPR85,PLCL1,PDZRN4,PMP22,LRRN3,VSTM2L,PRPH,RELN,PTH1R,PTPRH,RIPOR1,FAT4,ENOX1,MORC4,RGS4,ZFHX4,ROBO2,MELTF-AS1,RTN1,TNFRSF19,SMPD3,PEAR1,CCDC92,SYBU,TRIM67,DMRTC1,SMARCD3,SNAP25,CABCOCO1,ANKFN1,CLSTN2,ITPRID2,SST,ZEB1,PCDHGB6,DNAH7,TMEM121,ZFPM2,RP9P,HEY1,ASXL3,TLR4,RIMBP2,TNS1,DOK6,SYNPO2,LRRC24,PPIL6,FLRT2,TOM1L2,WNT7A,ZIC1,EMX2OS,CRB2,PRDM8,ADAMTS9,DNAH10,FAM13C,MSRB3,KLHDC1,DPF3,FAM181A,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE76381_iPSMoleculeCountsPMLog2 1.17E-08 5.66E-05 1.15E-07 1.04E-06 33 111 "NDRG3,SYT13,ANK2,ZSCAN18,CACNA1B,DLGAP2,CHGB,TMEM130,EDIL3,SEZ6L2,TMEM35A,RCAN2,NSG1,GNG4,STMN2,CELF5,MARK1,SAMD14,BEX5,PCSK1,PPP2R2B,VSTM2L,BDNF-AS,PTPRN,RTN1,ANKRD36,SNAP25,LMO3,PLCB1,VGF,CELF4,REEP1,NETO1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.17E-08 5.66E-05 1.15E-07 1.04E-06 33 111 "PCDH10,PTCH2,ATP1A3,DDR1,ARHGAP33,NRXN3,CRMP1,CSNK1E,ELMO1,DLX1,EDNRB,APC2,TUBB3,GAD1,ACSS1,RUNDC3A,DCLK2,FAM222A,MARK1,MBP,MSI1,MYT1,NNAT,TMOD2,RTN1,MAST1,SNAP25,TACC1,MCF2L,HEY1,UCHL1,CELF4,TMEM198" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.19E-08 5.77E-05 1.17E-07 1.06E-06 35 122 "PTCH2,ATP2B2,HAP1,MAP4K4,SLITRK5,DTNA,EPHB1,APC2,ADGRV1,REEP2,TUBB3,DLL3,SRRM4,STMN2,RNF165,TOX2,FRMD5,IGFBPL1,MAP2,ADAM22,NRCAM,GAL3ST4,CCDC112,HSPA4L,SP2,SEPT3,TCF4,MGAT5B,ZNF24,EML6,DPYSL5,STOX2,FZD3,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K3 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.22E-08 5.91E-05 1.20E-07 1.09E-06 43 168 "GALNT16,CCDC85A,WDR35,LTBP4,GPRASP2,CDC42BPA,PHYHD1,DDR1,LONRF2,SLC35F1,RUBCN,RUSC2,DMD,SHANK1,TMEM35A,CHST15,PPARGC1A,CELF5,MGAT3,NEXMIF,NCAM2,NELL2,NFIX,PCDH9,NLGN3,TMEM38A,POU6F1,PBRM1,ARMC5,MEG3,FHOD3,NLGN1,SMARCD3,CLSTN2,ANKRD12,KIAA1107,KCNE5,TUBB2A,CCDC136,TSPAN11,RBFOX3,NPDC1,SENP7" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.55E-08 7.54E-05 1.52E-07 1.38E-06 72 356 "KDM5D,NDRG2,ALCAM,ARHGAP20,LTBP4,AMH,ATP1A3,ADAM23,CACNA1G,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,LDB2,SCARB1,SLIT2,CNTFR,VCAN,RIPOR2,ARHGAP24,ARMCX2,CDON,EDNRA,HEYL,EGFR,MRO,PLXNC1,LRRC17,NRN1,DLC1,FLNC,AFF2,IQGAP2,GATM,GFRA2,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,KLHL23,LAMA2,LSS,MATN2,MEIS1,NEXMIF,PCDH9,FXYD1,PCDH18,PLTP,LRRN3,RASGEF1B,LAMA1,PTCH1,PTN,TMEM255A,ZCWPW1,ROBO2,ARMH4,MEG3,PKNOX2,SULF2,ADGRL3,ZFPM2,THRA,TRPS1,VSNL1,STOX2,ADAMTS9,WNK3,ST8SIA2" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k2 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.65E-08 8.01E-05 1.61E-07 1.46E-06 32 107 "TAOK1,LCORL,SGCE,CDH2,SRSF11,PLAA,RBM39,TCAF1,EPB41L2,SRRM1,ANKFY1,SMC2,APOPT1,SRCAP,MID1,MMP16,MSI1,CNOT4,PDPK1,KANSL1,TMLHE,NCBP3,ATXN2,FNIP1,SLC12A2,ZC3H13,SYNE2,R3HDM1,TRIM9,ADAMTS9,GAN,SENP7" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_200_k4 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.66E-08 8.04E-05 1.61E-07 1.46E-06 26 76 "PKP4,BACH1,RUNX1T1,SLIT2,COL4A5,ZC3H11A,EIF4G1,EPB41L2,LPAR4,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,PCDH9,PIK3R1,C1orf54,TMLHE,MEG3,TRA2B,PRRC2C,CBX5,R3HDM1,SSBP2,FLRT2" Coexpression Atlas BM Top 100 - putamen BM Top 100 - putamen Body Map 1.66E-08 8.04E-05 1.61E-07 1.46E-06 26 76 "ADORA2A,CPNE5,RGS9,CA12,CALB1,CDR1,LHX2,NGEF,CNR1,DGKB,PLPPR4,PPP1R1B,GAD1,CPLX1,CYP46A1,GNAL,CELF5,SOWAHA,PPP3CA,PRKCB,DDN,SST,RASD2,LAMP5,KCNAB1,MPPE1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.66E-08 8.04E-05 1.61E-07 1.46E-06 26 76 "SYT13,ANK2,CACNA1B,DLGAP2,CHGB,TMEM130,SEZ6L2,TMEM35A,RCAN2,NSG1,GNG4,STMN2,CELF5,SAMD14,BEX5,PCSK1,PPP2R2B,BDNF-AS,PTPRN,RTN1,ANKRD36,SNAP25,LMO3,VGF,CELF4,NETO1" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Subtype Smooth Muscle-like Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Subtype Smooth Muscle-like Myofibroblast Lungmap CCHMC 1.70E-08 8.26E-05 1.65E-07 1.50E-06 80 412 "EMILIN3,ZNF608,USP35,LCORL,MADD,TMEFF1,ZSCAN18,CHRD,RUNX1T1,DCLK1,VAX2,QKI,AKAP6,ABI3BP,NRG2,FAM171B,RNF14,CLIP3,DOCK4,GPRASP1,DAPK1,DMD,SHANK1,CASP8AP2,TSPAN5,YAF2,ELN,LRRC17,SPEG,MRPL10,MRVI1,FCGRT,FOXF2,MEGF10,DHRS4,MSL3,GPER1,GRB10,PARD3B,GSN,BVES,SHISAL1,NKD1,KCNK3,TMEM110-MUSTN1,SAMD14,TBC1D25,PALM,PDE4D,CYTL1,PFKFB3,PLEC,C19orf57,PPM1B,PRKAR1B,PSD,PTPRD,REV3L,RGS4,RIC8B,DCUN1D2,FBXW7,ADAL,CLIP1,ZNF667,FAM126B,IZUMO4,KDM4C,SPTAN1,ITPRID2,DNAJC9,ANKRD12,KAT6B,TPM1,TRO,TRPS1,UBE2H,ZNF32,MFF,JMJD1C" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.70E-08 8.27E-05 1.65E-07 1.50E-06 81 419 "KDM5D,KLHL13,ARHGAP20,MYRF,CACNA2D1,CALB1,KALRN,CBLN1,DCLK1,LARGE1,SLIT2,CNTFR,ZNF521,HAPLN1,CLIP3,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,DNM1,DRP2,TSPAN5,EDNRA,SEMA3D,PLXNC1,EMX2,MTSS1L,FAM198B,FGFR1,FLNC,DENND2A,FREM1,GHR,GLI2,ADGRA3,GPR37,GUCY1A1,GUCY1B1,NKD1,KCND2,KLHL23,MATN2,MEIS1,MEIS2,KITLG,MYO9A,NEFM,NNAT,PDE3A,PCDH18,PRKCB,LAMA1,PTN,PTPN13,TMEM255A,ZCWPW1,ZFHX4,ROBO1,ROBO2,GLDN,HUNK,RASA3,ST8SIA1,PKNOX2,KDM3A,UHRF1BP1L,ST5,ADGRL3,KLHL4,ZFPM2,ACTR6,ASXL3,TRPS1,FLRT2,PLEKHH2,PCDH20,LYPD6,WNK3,DPF3,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.72E-08 8.34E-05 1.66E-07 1.51E-06 59 270 "FMNL2,KLHL13,LRCH2,PPP4R4,IGDCC4,PDE8B,NUMB,INSYN2B,WASF1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,EMX2,MTSS1L,NRN1,OLFM1,NSG1,GPD2,IGF1,KLHL23,KITLG,AFF1,MYO9A,NPR2,NUCB2,SERPINI1,GDPD1,GDPD2,CNTLN,PTPRG,FAT4,ZFHX4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ZFP30,SLC4A3,KDM3A,UHRF1BP1L,LHPP,ST5,ADGRL3,RPGRIP1L,DNAH7,ACTR6,KAT6B,ZNF23,ELFN1,LYPD6,FRMD6,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE76381_ESMoleculeCountsPMLog2 1.77E-08 8.61E-05 1.71E-07 1.55E-06 37 135 "APLP1,CALB1,THSD7A,KALRN,RUNX1T1,IGDCC3,EBF1,SEZ6L2,EPB41,NRN1,ACSL4,MEX3B,NSG1,DLL3,STMN2,IGFBPL1,INSM1,L1CAM,MAP6,MEIS2,TAGLN3,NEFM,PCSK1,PRTG,PKIA,PRPH,C1orf54,ROBO1,RTN1,TNFRSF19,SLC6A8,SNCA,NFASC,ZEB1,ZIC1,CELF4,PCBP4" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000_k5 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.88E-08 9.12E-05 1.81E-07 1.64E-06 53 232 "INTS2,NME5,LCORL,LGR5,PDE8B,ASPA,INSYN2B,SYNJ1,ARHGEF7,CALB1,LONRF2,CNR1,GREB1,DOCK4,HDAC9,SACS,DYNC1I1,DRP2,DNAJB6,RASGRP1,ATP6V1H,ZMAT1,GGT5,AIFM3,MAP7D2,KCND2,MAP4,KITLG,MYO5A,NEXMIF,GLIPR1L2,PDPK1,ABCB1,SERPINI1,PPP2R5E,PRCD,FNIP1,TNFRSF19,HSPA4L,SYBU,CPEB4,SLC37A2,ANKRD12,DMXL2,DOCK9,CCDC173,DNAH7,ACTR6,RASD2,ZNF711,ZNF23,REEP1,PHTF2" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500 gudmap_RNAseq_e11.5_Ureteric_stalks_2500 Gudmap RNAseq 1.91E-08 9.27E-05 1.84E-07 1.66E-06 269 1900 "SYN3,ABHD6,AS3MT,NCKAP5,ADCY6,AXIN2,PLEKHH1,ADORA2A,KIAA1211,PCDH19,NME5,KIAA1324,AK2,CEP126,ZNF687,DOC2A,AMPH,AMT,FGD2,EPB41L5,APOC1,CPNE5,LGR5,CDC14B,ARHGDIG,PDE8B,ATP1A1,RGS11,RGS9,BCL7A,PROM1,BMP7,BMPR1B,WASF1,CA4,CA12,DDR1,CALB1,HAP1,HIP1R,MTMR7,CBFA2T2,LRBA,LONRF2,LRWD1,CRLF1,CBARP,CHGB,CHN2,B4GALT6,SLIT2,PPT2,MYL6B,FAM189A2,QKI,CNR1,IGDCC3,ZNF385A,SH2B1,HAPLN1,CRYM,IPCEF1,CST3,PLXNA4,FAM169A,PLCXD3,CTH,GREB1,HDAC9,KATNAL2,DAPK1,SPOCK2,MFAP3L,SNAP91,SGSM2,CDON,DPP6,DTNA,DUSP9,EDNRB,SEMA3D,APH1A,KCTD3,PLEKHA1,CERCAM,EMX2,HSD17B14,ENO2,ERBB2,ERBB4,SPEG,EYA1,CD320,REEP2,ST3GAL6,ZSCAN30,SPSB4,FGF12,EVL,SEMA4D,SYT3,C2orf88,POMT1,HVCN1,RASL10A,GALNT15,GALC,SYT17,IGSF5,TUBA8,NFU1,GFER,GGT7,PPARGC1A,RUNDC3A,TOX3,KIAA1958,KDM2B,POLL,LNX1,PLPP7,GRIK5,RNF165,GSTM5,GSTT2,SLC2A6,FAM222A,MUM1,PADI2,FRMD5,ACOT7,SHISAL1,IBA57,SLC6A17,SLC35G1,KCNJ16,KCNK3,GATD1,KHK,L1CAM,STMN1,SYTL4,MAPT,LYPLAL1,MATK,AQP11,MBP,ADAM11,KITLG,SAMD5,MSI1,TAGLN3,MYCN,LYRM9,NEFM,VWA2,NPY,NRCAM,KSR2,ZNF827,CDK18,PDE1C,PDE4A,PDE1B,FAM98B,PFKFB4,ZDHHC8,SEMA5B,RETREG1,PKM,KCTD15,PLCL1,SLC25A23,PLXNB1,SEPT4,POLR2F,FSD1,PPP1R1A,NKAIN4,MAPK4,GDPD1,LAMA1,ELOVL2,SPDL1,PTPN13,EML5,PTPRG,NKAIN1,TMEM231,FAM184A,SUSD4,ROGDI,RASGRF2,ZMAT4,RET,FIGN,KCTD17,NUDT11,C12orf49,ARMC5,PCMTD2,KIAA0895L,GLDN,RPS6KA2,EMID1,RTN1,SALL1,SCN2B,SCN8A,HES6,TNFRSF19,ZNF821,SH3BGR,SH3BP2,FAM102A,KIF16B,SHMT2,FHOD3,ST6GAL1,WDR37,PEX26,SLC8A1,ABTB1,INAVA,SOX11,NKAIN2,STAC2,KANK1,TMEM150C,SYP,SYT5,TBCEL,WSCD1,CUX2,CYB561A3,TMEM9,TK2,BEX4,LRRC24,DCBLD1,CA14,HSPBP1,RPRM,UBE2H,UCHL1,MTCH1,CCDC136,VLDLR,VSNL1,KLC2,ATP6V0E2,SPHK2,POLR3H,DPYSL5,ANKS1B,SH3GLB2,MEIS3,INTS3,ZXDA,SLC38A1,TMEM178A,CIAPIN1,SEMA3B,PCBP4,WNK2,FZD3,DOCK8,AP3B2,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_anlage of loop of Henle_1000 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.99E-08 9.68E-05 1.91E-07 1.74E-06 132 796 "RALGAPA1,ABHD6,PLEKHH1,BEND6,OSBPL6,DOC2A,OGT,C6orf89,APC,EPB41L5,PHYHD1,TNRC6C,ATP1A1,SLC4A4,CFLAR,PROM1,BMP7,DST,MTMR3,CA4,CACNA2D1,CALB1,CLDN10,USP2,DCLK1,CFL2,CLCN3,COL4A5,GAL3ST1,NCOR1,CRYM,GREB1,TM9SF4,TMEM170A,MFAP3L,CPEB2,DUSP9,DNM1L,GOLT1B,HIPK3,SEMA3D,EIF5,EMX2,VPS13B,EZH1,ST3GAL6,SEC24B,MED12L,FGF1,SPSB4,SUCO,SYNCRIP,SMC2,PDLIM5,GALC,RAPGEF6,IQGAP2,SYT17,IGSF5,GCNT2,PPARGC1A,KIAA1958,GRB10,FAM107A,ZHX1,SCIN,KCNJ16,KIF2A,LIMS1,NCOA7,CLEC18A,CHIC1,MEIS1,MID1,MITF,MKLN1,MYH3,CNOT4,NRCAM,OXTR,CNTN3,PDE1C,ENPP2,PIK3C2A,PDZRN4,SCHIP1,KANSL1,MAPK4,RELN,CNNM2,LAMA1,PTPRO,RASGRF1,REV3L,ROBO2,NCBP3,SALL1,SCN7A,SCN8A,ZFP2,FHOD3,NAPB,CPEB4,FAM126B,ZHX3,MYCBP2,DDN,NEK4,STX1A,KANK1,PRRC2C,ARHGEF9,VPS13A,DNMBP,MGRN1,WSCD1,SATB2,TRIM2,NSD1,ERCC6L2,RGMB,SSBP2,UGT8,VLDLR,EMX2OS,ADAMTS9,TMEM178A,DOCK8,MSRB3,NETO2,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 2.02E-08 9.81E-05 1.94E-07 1.75E-06 101 564 "CLK4,FAM135A,PKP4,APC,BBS2,SLC16A4,SEPT7,SRSF11,EPS15L1,HECTD1,CNN3,TBPL1,IGDCC3,CSNK1G3,DZIP3,PNPLA8,TBC1D5,KIAA0586,YTHDC1,KIAA0753,ZC3H11A,DNM1L,E2F6,EDIL3,KLHL5,EIF5,MRNIP,COQ7,MTSS1L,SRRM1,NSRP1,KAT8,SEC24B,ST6GALNAC3,OGA,RAPGEF6,C15orf41,ARFIP1,NFU1,DBF4,ADGRA3,DIDO1,ZHX1,ATXN2L,HSF2,LIMS1,MARK3,MEST,NEK1,FAM98B,PRIMPOL,EXOSC10,CEP41,RIPOR1,PPP2R3C,SETD5,GSTCD,ELP2,CLIP1,SCP2,TRA2B,CHD9,FNDC3A,EPN2,SEPHS1,ZNF334,CDK5RAP2,SPATA7,BDP1,UHRF1BP1L,MYCBP2,ZNF423,ZC3H13,RBM26,LARP4,MPRIP,NEK4,STXBP1,DNAJC9,TAF9,FAM208A,TBL1X,TCEA1,ZEB1,DICER1,SIRT1,AP4E1,TMPO,TRIO,TRO,ZKSCAN5,XPO1,ZNF711,ZNF142,ZSCAN26,ZFAND5,MAP3K12,KAT6A,HNRNPA3,JMJD1C,ZDHHC20" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.07E-08 1.01E-04 1.98E-07 1.79E-06 65 311 "SORCS2,ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,ISPD,ARHGEF25,CBLN1,SLIT2,CNTFR,ZNF521,VCAN,MYADM,RIPOR2,ARMCX2,DNM1,EDNRA,SEMA3D,EGFR,EPB41L2,LRRC17,EYA1,DLC1,FLNC,SEPT9,GFRA2,FREM1,GHR,GLI2,PRDM5,GUCY1A1,GUCY1B1,LAMA2,MEIS1,ZC3H12B,NEFM,NNAT,PCDH9,PCSK5,PLTP,SH3KBP1,LRRN3,LAMA1,PTCH1,PTN,TMEM260,ZIK1,PTPRD,TUG1,ROBO2,ARMH4,MEG3,SATB1,PKNOX2,ARFGAP1,SULF2,SYNE2,PJA1,ASXL3,TNS1,TPM1,PLEKHH2,STOX2,ST8SIA2" Coexpression Atlas PCBC_ratio_SC_vs_DE_500 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 2.08E-08 1.01E-04 1.98E-07 1.80E-06 92 499 "SYN3,UNC5A,VAT1L,PLA2G4C,ATP1A3,AZGP1,LDHD,CA4,CALB2,CCK,CHRNA4,RAB33A,CNTN1,CABP1,ANKRD35,C1QL2,ABCG1,SNCAIP,GALNT9,RIMS4,SEC14L5,RIPOR2,JAKMIP2,TMEM130,PARD6A,AASS,CALCRL,RASGRP2,PIPOX,OLFM1,HPCAL4,CGREF1,ACSS1,CPLX2,IGSF5,ALDH1L1,TTBK1,CCDC184,SOX21,LINGO1,FRMD3,INSYN1,LRRC75A,SCIN,ITGAM,KCNH2,KCNN2,KCNN3,KHK,CREG2,KIF5A,MX1,FXYD7,VWA2,NPTX1,NPTX2,NTRK3,PCSK1,NLGN3,FXYD1,PCDH18,SEPT4,EPB41L4B,NKAIN4,GDPD2,NCR3LG1,PTPRN2,PTPRO,PTX3,TMEM145,SUSD4,RADX,KCNIP1,FERMT1,TRERF1,LMO3,SOX21-AS1,SEPT3,RHBDL3,ARHGEF9,ARC,SYP,SYT5,TACR1,VAV1,VSNL1,TSPAN11,LGI4,CRB2,LAMP5,SLC30A3,KCNAB1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 2.12E-08 1.03E-04 2.01E-07 1.83E-06 32 108 "ATP2B2,SRSF11,SCRN1,DTNA,FSD1L,EPHB1,ADGRV1,CLVS1,AFF2,DLL3,SRRM4,TOX2,FRMD5,IGFBPL1,CELF5,KCNH2,MAP2,SHC3,TAGLN3,MAPK10,CXXC4,SOX11,SYP,WSCD1,CUX2,CLASP1,FRYL,MGAT5B,ZIC1,DPYSL5,WNK2,FZD3" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500_K3 facebase_RNAseq_e8.5_FloorPlate_2500_K3 Gudmap RNAseq 2.13E-08 1.03E-04 2.02E-07 1.83E-06 205 1374 "ABCF1,KIAA1211,ZNF608,NME5,CEP126,AMPH,PHF12,APLP1,UPRT,VAT1L,ARHGDIG,ARRB2,PTCH2,KIF1A,BARD1,BCHE,BID,PROM1,FUBP1,WASF1,MYRF,CA12,THSD7A,HAP1,PTBP2,MTMR7,ARHGEF1,CDH2,ZMYM4,LRRFIP1,CCPG1,TBRG4,CACNA2D2,CBARP,PPT2,CLCN3,FAM19A5,C4orf33,QKI,CNTFR,BAG4,NECTIN3,ZNF385A,SLC35F1,FAM171B,AKAP12,CRMP1,HAPLN1,CLIP3,FAM169A,CTH,GREB1,KATNAL2,TMEM170A,RUSC2,DDX46,POM121,CASP8AP2,DPP6,FAM78B,DUSP9,E2F5,SEZ6L2,EDN1,YAF2,PAN3,EPHB1,SRRM1,NCALD,EXTL2,CD320,REEP2,CEP78,PRMT5,OLFM1,POLR1B,SPSB4,AMOTL2,FHL1,IQCG,FLNC,NOP56,SYT3,COQ5,CINP,SMC2,USP21,PRELID3A,MTHFD2,GATM,CSDC2,GGT7,TCERG1,DBF4,GLI2,TOX3,KIAA1958,GNAO1,GPD2,LPAR4,STMN2,RABL2A,PSIP1,HSF2,LRRCC1,KIF2A,IPO5,KTN1,CAMK2N2,LSAMP,MAT2A,AQP11,MEST,PPM1L,ADAM22,MYCN,LINC00672,CNOT4,NOVA2,CLDN11,PDCD2,TMOD2,FAM98B,OLA1,SNX10,RETREG1,PKM,SLC25A23,PRIMPOL,PMP22,FSD1,PPP1R1A,NKAIN4,PRKCB,MASP1,RELN,LAMA1,GDPD2,PTCH1,ZIK1,PTPN13,EML5,NKAIN1,CEP97,CCDC40,FAM184A,PRRT2,ERI2,MORC4,FIGN,RFX3,NUDT11,LGI2,SETD5,ROBO1,RPL15,KIAA0895L,HUNK,KCNIP3,SALL1,MAPK12,KIF21A,FHOD3,CCDC92,ANKRD6,PKNOX2,TET1,PDZD2,SOX11,SPTB,RBM26,PBLD,POGZ,LARP4,NEK4,SEPT3,ANKRD28,MTCL1,CUX2,SIRT1,C18orf54,ITGB3BP,STXBP4,TST,EIF4ENIF1,USP1,CCDC14,LMF1,XPO1,ZNF23,ZFP41,ZNF184,SMARCAD1,EMSY,SLC38A1,STOX2,TUBA1A,WNK3,AMN1,FZD3,SMIM8,PHTF2,AAAS,NETO2,SPATA13" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 Gudmap RNAseq 2.15E-08 1.04E-04 2.04E-07 1.85E-06 138 843 "ACHE,NDRG2,ADCY6,ADD2,ADORA1,RNF150,C1QTNF1,TRMT9B,AMPD3,BCAS1,ARRB1,PDE8B,RASL11B,MYOM1,NRP2,GPR146,CACNA2D1,DLGAP1,UBE2L6,NRXN3,IGLON5,ARHGEF6,AATK,CST3,DGKB,ZNF804A,SGSM2,NR1D2,EBF1,EDN1,HEYL,FRY,OPTN,RCAN2,LRRC17,RASGRP2,SPEG,TLR7,RASL12,MRVI1,ST3GAL6,CHST15,FCGRT,FGF1,FHL1,ZMYND15,SPECC1,TPPP3,HIGD1B,TUBA8,GDF9,GGT7,GGT5,LOXL3,FERMT2,CCDC184,STON1,GSN,GSTM5,GSTT2,GUCY1A1,GUCY1B1,SLC2A6,ATOH8,FRMD3,HLF,SYNPO,IFI16,IL6R,IL6ST,INPP5B,ITGA7,KCNJ5,KCNK3,TTYH2,GPR155,MAP6,MAPT,MARK1,SHC3,MITF,MMP17,NRBP2,MX1,RTL5,NCF2,NTRK2,P2RX7,PDE3A,ABCB1,SERPINI1,PIK3R1,PLCB2,PLCL1,PLEC,FXYD1,PCDH18,PLTP,SEPT4,PPARA,PRKAB2,PKIA,PTH1R,PTN,PTPN13,FAM184A,ZDHHC14,ZMAT4,PRRT2,RGS4,EMID1,PRCD,PEAR1,PREX2,SLC8A1,SLC12A2,CPEB4,CABCOCO1,UNC5B,DBNDD2,ITPRID2,NKAIN2,RGL1,SYP,PDLIM2,TNS2,GPRIN3,GALNT17,TLR4,TNS1,IL34,PLEKHH2,ZBTB38,SH3GLB2,FAM13C,DOCK8,MSRB3,CPNE4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 2.27E-08 1.10E-04 2.15E-07 1.95E-06 113 654 "EMILIN3,RTL9,SEMA6A,SRPX,CDK10,IGDCC4,SPTBN4,RASL11B,BMPR1B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDO1,CRLF1,DIS3L,CLTB,PCYT1B,COL9A3,ABI3BP,ENTPD4,ANKRD44,SNCAIP,BOC,ARHGAP24,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,EBF1,MBNL2,LRRC17,DENND4A,HSPA12B,FCGRT,FDFT1,SCARA3,FOXF2,TRIM16,NSG1,STAU2,TRAF3IP2,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,RASSF8,BACH2,HLF,SYNPO,IGF1,INPP1,ITPKB,JAK2,LAMA2,LAMP2,SMAD9,MAN2A2,SRSF12,MSR1,N6AMT1,FXYD7,NFIX,NPY,ZNF827,CNTN3,PDE3A,PDE4D,PFKFB2,SDK2,EPB41L4B,CCDC144B,DIRAS2,CNTLN,IQSEC3,FAT4,BEND5,MORC4,ZFHX4,MRAP2,BAALC,DGLUCY,SH3GL3,CNKSR2,DZIP1,SLC8A1,SMARCC2,RCOR3,PDZRN3,DOP1A,CDK19,ARHGEF9,PLCB1,TACR1,ANKRD12,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPS1,TSPAN11,WIPF1,ZNF32,NAV3,ADAMTS10" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000 DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.31E-08 1.12E-04 2.18E-07 1.98E-06 129 775 "RALGAPA1,ABHD6,OSBPL6,TAOK1,FAM135A,AMPD3,OGT,APAF1,APC,EPB41L5,TNRC6C,PDE8B,SLC4A4,GPR146,CFLAR,BMPR1B,WASF1,CA4,CA8,CACNA2D1,CALB1,RGN,LRBA,DCLK1,CFL2,B4GALT6,SLIT2,CLCN3,FAM149A,COL4A5,NECTIN3,SLC35F1,RBM39,OSBPL3,IPCEF1,DZIP3,CTH,ARHGAP32,ARHGAP24,AIF1L,MFAP3L,PLPPR4,PDCD6IP,SEMA3D,EIF5,IRAK4,TENM1,EMX2,ENO2,SLC43A2,EZH1,ST3GAL6,MED12L,SPSB4,SUCO,SYNCRIP,C2orf88,SMC2,PDLIM5,CAMKK2,GALC,RAPGEF6,IQGAP2,SYT17,IGSF5,TUBGCP4,SRCAP,GHR,PPARGC1A,GRB10,PADI2,ICA1,SCIN,IL6ST,SLC35G1,KCNJ16,KIF2A,L1CAM,NCOA7,AQP11,CHIC1,KITLG,MKLN1,MYO6,VWA2,PFKFB2,PIK3C2A,PSAT1,SCHIP1,DRAM2,KANSL1,MAPK4,EML5,FAM184A,RASGRF2,RET,REV3L,SALL1,SCN8A,TRA2B,HKDC1,SLC8A1,NAPB,LIMCH1,FAM126B,BDP1,ZHX3,MYCBP2,ATP10B,KANK1,PRRC2C,VPS13A,NUDT10,TMEM150C,MGRN1,CUX2,ERCC6L2,RGMB,DCBLD1,SSBP2,RPRM,UGT8,VLDLR,EMX2OS,LYPD6,DOCK8,NETO2,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.33E-08 1.13E-04 2.20E-07 1.99E-06 31 103 "LTBP4,GPRASP2,LONRF2,LHX2,RUSC2,DMD,SHANK1,DTNA,MAMLD1,TMEM35A,APC2,CHST15,TPPP3,PPARGC1A,NEGR1,ZIC5,NEXMIF,NCAM2,NELL2,PCDH9,SEMA5B,TMEM38A,POU6F1,STX1B,NLGN1,CLSTN2,RHBDL3,CUX2,KCNE5,ZIC1,SENP7" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.41E-08 1.17E-04 2.27E-07 2.06E-06 20 49 "CACNA1B,CHGB,CNR1,CNTN1,MYRIP,PLCXD3,GRIN3A,STMN2,MAP4,NCAM2,NEFM,NTRK2,SLC10A4,NALCN,MAPK10,PRPH,RET,RGS4,RTN1,SNAP25" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.54E-08 1.24E-04 2.39E-07 2.17E-06 41 160 "EMILIN3,ESYT2,ADRB2,SRPX,ARHGAP20,TNRC6C,CACNA2D1,CHN2,NRXN3,CNTN1,COL9A1,AKAP12,PLXNC1,NCALD,ETV1,MRVI1,MEGF10,GFRA2,RAB40B,CACFD1,NEGR1,LAMA2,CHIC1,NDP,NTRK2,CLDN11,NALCN,PTX3,RASGRF1,LGI2,RYR3,LRFN5,SH3BGR,SH3GL3,PLCB1,SYNPO2,TRPS1,FLRT2,TRIM9,PLSCR4,SOCS4" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_k3_500 kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.57E-08 1.25E-04 2.41E-07 2.18E-06 42 166 "ADORA1,LGR5,BCL7A,BMPR1B,CACNA1G,CHN2,SLIT2,GREB1,SCRN1,SV2B,EMX2,HSD17B14,IGSF5,TOX3,KDM2B,ADGRA3,CLEC18A,TM6SF1,MID1,MSI1,NPY,PRTG,KCTD15,PLXNB1,SDK2,MAPK4,LAMA1,PTPN13,ROBO1,GLDN,FHOD3,CNKSR2,PDZD2,SOX11,NUDT10,TACR1,CUX2,HEY1,TRPS1,SLC38A1,ADAMTS9,SPATA13" Coexpression Atlas Arv_SC_fibroblast_2500_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 2.60E-08 1.26E-04 2.43E-07 2.20E-06 173 1120 "KCNH8,SYN3,TMEM132B,ADCY8,GALNT13,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,TMEM108,KIF1A,CARMIL3,ADGRB1,CACNA1G,HAP1,CLDN10,CCK,MTMR7,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,FAM19A5,SULT4A1,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,KATNAL2,KIF26A,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,PARD6A,CHRDL1,DPP6,SEZ6L2,AASS,PIPOX,ADGRV1,PPP1R1B,ZNF589,OLFM1,FGFR1,HPCAL4,FLT1,SYT3,CSPG5,TVP23A,MEGF11,MEGF10,HRASLS5,GABRA3,GABRB3,SRRM4,IGSF5,GCK,GDF1,TTBK1,KDM2B,GNAL,GNG4,LPAR4,GRIK5,GRIN2D,LINGO1,PSIP1,PADI2,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KIF5A,CAMK2N2,CHST6,MPP2,ADAM22,MYCN,TCEAL5,FXYD7,NEFM,NELL2,NNAT,PCBP3,NLGN3,SEMA5B,JAKMIP1,PURG,PSAT1,NECAB2,MAGEL2,PPP2R2B,PPP2R2C,LAMA1,GDPD2,PTPRD,PTPRN,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,RET,PTGR2,HUNK,SALL1,TMEM200C,PPM1E,CNKSR2,PREX2,SEPHS1,TET1,MAST1,SOX3,NMNAT2,HECW1,SOX21-AS1,SEPT3,RHBDL3,NUDT10,ARC,SYP,SYT1,COBL,KLHL4,FAM189A1,SLC19A3,PCDHA3,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,KCNE5,CA14,CLEC2L,UGT8,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,DPYSL5,CADM2,GAL3ST3,RGS7BP,TMEM63C,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k3_1000 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.61E-08 1.27E-04 2.44E-07 2.21E-06 95 523 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,BIN1,MAP4K3,APBB2,SHROOM2,ATP1B3,DOCK11,NRP2,ARHGEF7,LDB2,CD38,MS4A7,ABCG2,MAP4K4,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,LRRC3B,USP6NL,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,EBF1,EDN1,EDNRB,PHF20L1,CALCRL,RASGRP2,DENND4A,IGSF6,CORO2B,DLC1,FLT1,UFM1,PDLIM5,FYB1,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,GRIA2,MAP4K5,NCKAP1L,ELOVL5,ZDHHC15,ICA1,ITPKB,LIFR,LMO2,PIK3AP1,TM6SF1,MEF2C,MEST,MSR1,MYO6,PDE4B,ABCB1,PLCL1,MINDY2,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,SLA,PREX2,BTBD3,CPEB4,LIMCH1,THSD1,PLCB1,KLHL4,TCF4,TEK,HEY1,WIPF1,ZNF711,NAV3,PLD4,FAM13C,DOCK8,ZDHHC20,RNF146,SPATA13" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K2 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 2.62E-08 1.27E-04 2.45E-07 2.22E-06 76 388 "PLEKHH1,MTA3,ZNF608,WDR35,SEMA6A,UNC79,FAM135A,SYT13,ZNF687,PDZD4,DPP10,EPB41L5,VAT1L,SEMA4G,PRX,PPP4R4,IGDCC4,STK33,ZBTB10,RASL11B,TMEM108,PTBP2,PLEKHB1,FAM19A5,KATNAL2,AIF1L,DPP6,DHX35,SHISA6,CELF5,FA2H,FSD1,NKAIN1,ACSS3,FAM184A,KHDRBS2,ZMAT4,FIGN,RIC8B,NUDT11,LGI2,ZNF532,SETD5,PNMA8A,ZC3H14,ZNF331,SEMA6D,CSRNP3,ZNF821,PREX2,TET1,NECAB1,PJA1,SLC19A3,NSD1,KHDC1,CHST8,GALNT17,BHLHB9,TTTY15,CCDC136,CFAP298,SPHK2,TCEAL7,ANKS1B,SMARCAD1,MEIS3,DHX33,SLC38A1,STOX2,ITM2C,WNK3,TMEM63C,ACTR3B,NETO1,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 3.09E-08 1.50E-04 2.87E-07 2.60E-06 43 173 "ATP2B2,MPDZ,JAZF1,HAP1,LHX2,IQCK,KATNAL2,JAKMIP2,DLX1,MAMLD1,SLC43A2,ATP2C1,OGA,C15orf41,SRRM4,KIAA1841,PCLO,TOX2,IGFBPL1,USP51,INSM1,KTN1,PAXBP1,MAP2,SHC3,ADAM22,MYT1,GPR137C,PAX6,ELOVL2,ENOX1,GAL3ST4,CASC3,KIF21A,LMO3,STAU1,SYNE2,BHLHB9,NR2E1,UCHL1,ZNF23,KAT6A,SENP7" Coexpression Atlas GSM538266_500 "Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2" "Immgen.org, GSE15907" 3.25E-08 1.58E-04 3.02E-07 2.73E-06 74 376 "RNF150,PTCHD1,ALCAM,FGD2,CASK,ATP1A3,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,ZNF385A,CSF1R,CSF2RA,CST3,USP6NL,CYBB,DOCK4,HDAC9,MYADM,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,GATM,GCNT2,MALT1,RAB30,ADAP1,ZNF496,GSN,FRMD5,LRRC25,IL6R,ITGAM,JAK2,KIT,LIFR,ADAM11,MEF2C,ADAM22,MYO5A,ABCB1,PLTP,RASGEF1B,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,KIAA0930,TNS1,NPL,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.51E-08 1.71E-04 3.25E-07 2.95E-06 55 249 "HECW2,PCDH10,LCORL,ADAM23,CBLN1,DCLK1,CDO1,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,PITPNC1,TIAM2,SPOCK3,EDNRA,EGFR,TENM1,SCML2,FOXF2,MEGF10,TOX3,ADGRA3,LPAR4,GRIA2,IFI16,LSAMP,PCDH8,PDE4D,ENPP2,NLGN3,LRP12,ING3,EPB41L4B,PTPRE,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,SATB1,CSRNP3,TNFRSF19,TROVE2,TTBK2,KLHL7,CAMTA1,ADGRL3,TCF4,PCDHB15,UGT8,WIPF1,PCDH20,FAM13C,SOCS4" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.01E-08 1.95E-04 3.71E-07 3.36E-06 72 364 "KDM5D,ALCAM,ARHGAP20,LTBP4,AMH,CDC14B,CADPS,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SCARB1,SLIT2,ZNF521,VCAN,RIPOR2,ARMCX2,EDNRA,EGFR,MRO,PLXNC1,LRRC17,NRN1,FAM198B,PTK2B,DLC1,FGF13,FLNC,AFF2,TRAF3IP2,IQGAP2,GATM,GFRA2,FREM1,GHR,PPARGC1A,GLI2,ADGRA3,GUCY1A1,GUCY1B1,KLHL23,MATN2,MEF2C,MEIS1,PCDH9,PCDH18,PLTP,LRRN3,RASGEF1B,MASP1,LAMA1,PTCH1,PTN,TMEM255A,REV3L,ROBO1,ROBO2,ARMH4,GLDN,ST5,SULF2,ADGRL3,OBSL1,ZFPM2,THRA,TPM1,TRPS1,VSNL1,STOX2,ADAMTS9,WNK3" Coexpression Atlas BM Top 100 - vestibular nuclei superior BM Top 100 - vestibular nuclei superior Body Map 4.05E-08 1.97E-04 3.74E-07 3.39E-06 24 69 "SMIM17,SYT13,CALB2,SYNGR3,GABRG2,GAD1,GPR37,STMN2,ARHGAP36,KCNJ16,MAP2,MAP4,MBP,NEFM,NEFH,TMEM255A,SNAP25,SNRPN,SPP1,SST,SYT1,UGT8,P2RY12,FSTL5" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 4.11E-08 2.00E-04 3.79E-07 3.43E-06 26 79 "ATP2B2,JAZF1,HAP1,IQCK,KATNAL2,JAKMIP2,DLX1,MAMLD1,SRRM4,KIAA1841,PCLO,IGFBPL1,INSM1,MAP2,SHC3,ADAM22,MYT1,GPR137C,PAX6,ELOVL2,ENOX1,LMO3,NR2E1,UCHL1,ZNF23,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.37E-08 2.12E-04 4.02E-07 3.64E-06 21 55 "ANK2,ADAM23,FAM171B,ERC2,RIMS2,JAKMIP2,ZNF804A,SPOCK3,RAB39B,GABRB3,GNAO1,GRIA2,NCAM2,NEFM,NOVA1,STK32A,EML5,KIF21A,SNAP25,CUX2,FSTL5" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.38E-08 2.13E-04 4.02E-07 3.64E-06 39 151 "USP31,ARHGAP20,APC,SLC4A4,CACNA2D1,CALB1,CHGB,COL9A1,ELMO1,EBF1,EDNRB,HIPK3,SEMA3D,CALCRL,DLC1,GFRA2,RAB40B,RASSF8,IFI16,RBPJ,LSAMP,MATN2,NTRK2,CLDN11,PIK3C2A,PTX3,TMEM255A,RGS4,LGI2,ZHX3,CLASP2,ARHGEF9,TEK,ZFPM2,RGMB,TRPS1,PCDH20,KCNAB1,SOCS4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k4 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.42E-08 2.15E-04 4.05E-07 3.67E-06 43 175 "ARHGAP20,PKP4,DOCK11,BACH1,IL33,RUNX1T1,ZNF445,SLIT2,COL4A5,AIF1L,ZC3H11A,CDON,EDNRA,EIF4G1,LPAR4,RASSF8,HAS2,MAP4,CHIC1,MEIS1,MEIS2,SAMD5,PCDH9,NALCN,PIK3R1,PTN,TMEM255A,C1orf54,RNASEL,MEG3,TRA2B,CHD9,TET1,TROVE2,PRRC2C,SYNE2,PCDHB9,CBX5,TRPS1,SSBP2,UBE3A,FLRT2,VLDLR" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Lungmap Mouse Lung E16.5 Matrix fibroblast Lungmap CCHMC 4.53E-08 2.20E-04 4.13E-07 3.75E-06 80 421 "NDRG2,AXIN2,ADRA1B,ALCAM,SRPX,ABCD2,LTBP4,PPP4R4,RUNX1T1,CDO1,SLIT2,MAGED1,ABI3BP,CNRIP1,RBM39,AKAP12,VCAN,BOC,DOCK4,MYADM,ARHGAP24,BRINP1,HEPH,TIAM2,RCAN1,DTNA,EDNRA,PLXNC1,RGS17,PCOLCE2,ELN,LRRC17,RASGRP2,MTSS1L,RASL12,DLC1,FGFR3,FHL1,CPLX2,GFRA2,FREM1,GHR,GSN,GSTM5,LAMP2,MAN2A2,MAPT,MEIS1,MYO6,NRCAM,SETD4,PKD1,FXYD1,PMP22,SEPT4,NKAIN4,MAPK7,VPS13C,PTPRD,PID1,FAT4,ROBO1,ROBO2,RYR3,SCP2,ABLIM3,PREX2,LIMCH1,ADAMTS17,TACC1,PDLIM2,PCDHGA6,HIF3A,TNS1,PLEKHH2,VIPR2,VLDLR,ADAMTS9,ST7,ADAMTS10" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_500 kidney_P1_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.53E-08 2.20E-04 4.13E-07 3.75E-06 59 277 "RNF157,ALCAM,AMPH,BCHE,BCL7A,BMP7,DST,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,SPOCK2,GSDME,SNAP91,ARRDC4,DTNA,EDNRA,CALCRL,ETV1,RRAGB,EYA1,ST3GAL6,FGF1,FGFR1,MAD2L2,SCARA3,IGSF5,FREM1,TDRKH,CNTRL,FAM107A,HAS2,NEGR1,KHK,MEIS2,MEST,MMP16,NME4,NPR2,CNTN3,TSPY26P,ROBO2,SALL1,SLC4A3,SLC12A2,GKAP1,SULF2,ADAMTS17,CUX2,PCDHB9,TPM2,SLC38A1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 4.79E-08 2.33E-04 4.36E-07 3.95E-06 107 618 "METAP1D,SLC24A4,HECW2,TBC1D14,KIAA1324,SORCS2,SMIM17,ARHGAP20,GAS7,APOC2,LGR5,ZFYVE28,ARRB2,PDE8B,ATP1A3,ADGRB2,BARD1,NRP2,ZNF599,KSR1,IL33,LDLRAD4,CFAP410,CA12,CAMK2A,CAMK2B,KCNAB3,CCPG1,VAX2,BAG4,CREM,HAPLN1,CRYBB1,CSF1R,TIAM2,DRP2,SNX29,TMTC1,RASA4,RASGRP2,NCALD,CDKL3,PTK2B,CORO2B,ZMYND15,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,NTNG2,GNG4,ADAP1,GUCY1B1,KNDC1,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,MYO6,NEXMIF,NPR2,ETFRF1,PDE4B,PDE4D,ENPP2,PDPK1,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,GDPD2,STRC,PID1,ZCWPW1,ZNF493,ZMAT4,DUSP15,MORC4,PRIMA1,KCNIP3,LRFN5,MRAS,SGK1,ASAP3,CCDC92,INAVA,DOK5,IQSEC2,SAMSN1,ADGRL3,FAM189A1,LRRC24,KCNE5,FLRT2,MICU3,EML6,LAMP5,CADM2,DNAH10,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_1000 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.20E-08 2.52E-04 4.72E-07 4.28E-06 94 523 "CCDC85A,ADORA2A,HECW2,ADGRF5,MAP4K3,APAF1,APBB2,SHROOM2,ARRB1,ATP1B3,ADAM15,NRP2,PROM1,ARHGEF7,THSD7A,CD38,LRRFIP1,ABCG2,TMEM184B,MAP4K4,LY86,CDC42BPB,CRMP1,HAPLN1,CSF1R,USP6NL,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,SACS,FAM107B,EBF1,EDNRB,CALCRL,RASGRP2,DENND4A,CORO2B,DLC1,FLT1,UFM1,PDLIM5,TRIM16,FYB1,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,STMN2,GRIA2,MAP4K5,NCKAP1L,ICA1,LMO2,TM6SF1,MEF2C,MID1,PDE4B,PDE4D,ABCB1,PLCL1,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,RGS3,SGK1,MYO18A,PREX2,BTBD3,CPEB4,LIMCH1,UNC5B,SAMSN1,THSD1,PLCB1,KLHL4,FRYL,TEK,C18orf54,HEY1,TLR4,WIPF1,GDPD5,NAV3,FAM13C,DOCK8,ST7,NHSL1,ZDHHC20,SPATA13" Coexpression Atlas GSM538265_500 "Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 5.72E-08 2.78E-04 5.19E-07 4.70E-06 76 395 "FMNL2,PTCHD1,ALCAM,FGD2,CASK,ATP1A3,ADAM23,ST3GAL5,DDR1,HAP1,CHN2,B4GALT6,LY86,ZNF385A,CDC42BPB,CSF1R,CSF2RA,CST3,USP6NL,CYBB,DOCK4,HDAC9,MYADM,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,SPECC1,GATM,GCNT2,RAB30,ADAP1,GSN,LRRC25,IL6R,ITGAM,JAK2,KCNJ16,KIT,ADAM11,MEF2C,LINC00672,MYO5A,MYO9A,ABCB1,PLTP,RASGEF1B,PTK2,TMEM231,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,KIAA0930,CYB561A3,TNS1,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k1 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.75E-08 2.79E-04 5.21E-07 4.72E-06 46 195 "METAP1D,VAT1L,CASK,ZSCAN18,CACNA2D1,RUNX1T1,ARHGEF25,CDH2,DCLK1,RCBTB2,ZNF521,CLIP3,GPSM1,DNAL1,RHOBTB1,DYNC1I1,ADGRV1,UBE2E3,MEX3B,ZBED3,BRD8,GPT2,PSIP1,HAS2,CPT1C,MEIS2,ZNF827,GPR173,PLTP,CEP41,PKIA,TSPY26P,RNASEL,ZFHX4,TMLHE,SATB1,ZNF423,TROVE2,CLSTN2,ZC4H2,SULF2,TCF4,KAT6B,TPM2,WNK3,RTN4" Coexpression Atlas parathyroid gland parathyroid gland Human Protein Atlas 6.16E-08 2.99E-04 5.57E-07 5.05E-06 69 347 "AS3MT,USP35,ALCAM,AMPD3,DDO,PTCH2,RASL11B,ADAM23,CA8,LURAP1,MTMR7,CDH2,CHN1,PLEKHB1,CHRNA4,CCDC151,NRG2,IGDCC3,PYGO1,KATNAL2,SACS,SPOCK3,RCAN1,SEZ6L2,EYA1,FGF13,ZMYND15,ATP13A4,IQGAP2,SYT17,NTNG2,TDRKH,GRIK5,RNF165,GAREM2,KCNJ16,STXBP5,PPM1L,MPP2,SAMD5,MAPK4,HYDIN,CNNM2,NCR3LG1,ELOVL2,PTN,PTPRD,PTPRG,RET,LGI2,SGSM1,KCNIP3,RYR3,LRFN5,ABLIM3,OGDHL,MCF2L2,PLCB1,ADGRL3,FAM189A1,PCDHB6,PCDHAC2,RELL2,RIMBP2,LRRC24,CLEC2L,VLDLR,TIGD6,AP3B2" Coexpression Atlas GSM854297_500 "Plasmacytoid, DC.pDC.8+.MLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-2" "Immgen.org, GSE15907" 6.31E-08 3.07E-04 5.70E-07 5.17E-06 78 410 "ABHD6,FMNL2,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ATP1A3,SEC11C,ZNF599,DDR1,CD38,STOML1,LY86,MAGED1,ZNF521,CST3,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,ARRDC4,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,CHST15,FGFR1,PRKAG2,HVCN1,AK8,FYN,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,ADAM11,MEF2C,PPM1L,MYO5A,P2RY13,NUCB2,PLTP,TMEM231,ROGDI,ZDHHC14,PPM1E,ST8SIA1,CCDC88A,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,CYB561A3,SLC44A1,TNS1,C9orf85,P2RY12,LAT2,EVI5,SIGLEC10,PLD4,RGS7BP" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k5_1000 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.66E-08 3.23E-04 6.00E-07 5.44E-06 52 234 "INTS2,TAOK1,LCORL,INSYN2B,RNF182,CALB1,SOCS6,PLAA,CNR1,AKAP5,RBM39,DZIP3,GREB1,DOCK4,DRP2,CALCRL,EMX2,FAM198B,TUBGCP4,KCND2,KITLG,NEXMIF,CNOT4,PDPK1,SERPINI1,JAKMIP1,PPP2R5E,PTPRG,TMLHE,PCMTD2,SATB1,FNIP1,STUM,SYBU,SLC12A2,CPEB4,LARP4,SYNE2,SLC37A2,ANKRD12,DMXL2,SIRT1,ACTR6,TSC1,TBC1D15,RICTOR,ZNF711,ZNF23,TRIM9,EMX2OS,REEP1,ADAMTS9" Coexpression Atlas gudmap_RNAseq_e15.5_Podocytes_2500_K0 gudmap_RNAseq_e15.5_Podocytes_2500_K0 Gudmap RNAseq 7.01E-08 3.40E-04 6.30E-07 5.71E-06 174 1144 "EMILIN3,TMCC3,ADORA2A,SORCS2,ADGRF5,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PITPNM2,AMPH,PI16,MYH7B,GAS7,CPNE5,IGDCC4,MARK4,PTCH2,ADAM15,ADGRB2,CFLAR,KSR1,SYNJ1,ST3GAL5,IL33,LDLRAD4,CALB1,THSD7A,LDB2,CD38,CHGB,CHN2,PPT2,TMEM184B,HOMER3,CNTFR,CNRIP1,CDC42BPB,AKAP12,ABCG1,CRYM,SNCAIP,CSF1,PLCXD3,CYBB,DOCK4,MYADM,KIF26A,BRINP1,ELMO1,SNAP91,FAM107B,SHANK1,SEZ6L2,TSPAN5,EDNRB,TMTC1,RASA4,CERCAM,CALCRL,EIF1,EMX2,STX2,NCALD,SPEG,HSPA12B,REEP2,F8,FAM198B,OLFM1,SCARA3,FLNC,FLT1,POMT1,HVCN1,ST6GALNAC3,NSG1,MEGF11,GATM,SESN1,FREM1,CSDC2,GGTA1P,LYVE1,NTNG2,GPR12,LINGO1,FAM222A,MUM1,INSYN1,ACOT7,NEGR1,IGF1,NKD1,ITPKB,KCNK3,LMO2,MATN2,TM6SF1,MEF2C,MEIS1,KITLG,MOV10,MYO6,MYO7A,NEXMIF,NME4,NPY,NOVA2,CLDN11,ENPP2,SEMA5B,PMP22,NKAIN4,MASP1,SNRK,PTPRB,PTPRO,PTX3,RIPOR1,TMEM255A,C1orf54,RET,KCTD17,LGI2,ROBO2,GLDN,SALL1,MAPK12,PRCD,COPZ1,RASA3,ST6GAL1,NLGN1,ST8SIA1,LIMCH1,KDM4B,FAM219A,PDZD2,ARHGAP26,LHPP,CLSTN2,SAMSN1,THSD1,SST,STAC2,KANK1,STXBP1,PLCB1,TMEM150C,TAL1,KLHL4,TEK,ZFPM2,CHST8,TMEM9,HEY1,NPL,LRRC24,HSPBP1,RPRM,FLRT2,PLEKHH2,KCNT2,ATP6V0E2,REEP1,GDPD5,ADAMTS9,TMEM178A,CIAPIN1,NAV3,PLD4,DPF3" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.51E-08 3.65E-04 6.73E-07 6.10E-06 135 837 "RALGAPA1,ABR,KLHL32,ADORA1,USP31,ALCAM,DOC2A,OGT,SEMA7A,APBB2,EPB41L5,PHYHD1,ASPA,RIPK1,KSR1,BMP7,ST3GAL5,CA4,CACNA2D1,THSD7A,KALRN,HIP1R,CD38,LRRFIP1,CACNA2D2,CLCN3,ENTPD4,RBM39,RNF14,CRYM,PPP1R16B,RIPOR2,ARHGAP24,AIF1L,ALKBH8,TMCC2,CD99L2,HEYL,OPTN,EIF5,SRPK3,CALCRL,EIF1,RASGRP2,EPHB1,CD320,EZH1,CORO2B,DLC1,RACK1,ST3GAL6,MED12L,FGF1,SPSB4,FGFR1,FLT1,SMC2,PDLIM5,CGREF1,GALC,IQGAP2,SRRM4,CPLX2,IGSF5,PCDH17,GGT5,AIFM3,FERMT2,GPER1,GRB10,PARD3B,SYNPO,HP,KCNJ16,KIF2A,LMO2,CLEC18A,MAPT,KITLG,MSI1,LYRM9,NCF2,OXTR,PDE4B,SERPINI1,PIK3C2A,RETREG1,SCHIP1,MBOAT7,IRX1,KANSL1,RELN,PTH1R,PTPRD,PTPRO,RIPOR1,FAM184A,DUSP15,REV3L,RGS3,ROBO2,EMID1,SALL1,MAPK12,SCN7A,GALNT10,ANKRD6,PREX2,SLC12A2,SNCA,MYCBP2,DDN,APOM,STX1A,TMEM150C,TAF9,PDLIM2,MGRN1,WSCD1,ARHGAP9,TMEM9,HEY1,CBX5,TLR4,ERCC6L2,R3HDM1,RGMB,TRIO,SSBP2,ZNF23,GDPD5,TMEM178A,SEMA3B,RNF170,MSRB3" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k1 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.51E-08 3.65E-04 6.73E-07 6.10E-06 37 142 "RNF150,OSBPL6,ARHGAP20,SYT13,DPP10,TNRC6C,ADGRB3,CHGB,CNTN1,RIMS2,GRIN3A,EBF1,PLXNC1,MRVI1,MEGF10,FREM1,PTPRT,NEGR1,MMP16,MN1,NTRK2,CLDN11,PDE1C,PTX3,ZFHX4,KIRREL1,MEG3,CSRNP3,LRFN5,ST8SIA1,SLC14A1,CXXC4,NEK4,PCDHB3,RGMB,MRPL47,NETO1" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k1 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.68E-08 3.73E-04 6.86E-07 6.22E-06 38 148 "ADCY5,ATP2A2,MYOM1,NRP2,CACNA2D1,ABI3BP,DMD,CPEB2,DTNA,NCALD,MRVI1,FHL1,IGSF5,GCNT2,PRUNE2,BVES,HNMT,IFI16,IL6ST,MBNL1,NPTX2,PDE4D,PRKCB,RYR3,STUM,SH3BGR,FHOD3,LIMS2,FNBP1,DBNDD2,ENHO,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,ADAMTSL3,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.73E-08 3.75E-04 6.89E-07 6.24E-06 41 166 "METAP1D,ADCY8,AMPH,VAT1L,SEMA4G,CACNA2D1,CACNB4,CH25H,FAM19A5,ZFP28,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,DYNC1I1,DTNA,TMEM35A,EYA1,FGF1,SCARA3,MEGF10,GABRB3,FUT10,FAM107A,FRMD3,NEGR1,CNTN3,PPP2R3C,ENOX1,ROBO2,RPS20,SALL1,ZFP2,SUPT20H,HSPA4L,ANKRD6,SLC12A2,NEK4,TPM2,ZFAND5" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 2 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 2 Lungmap CCHMC 7.73E-08 3.75E-04 6.89E-07 6.24E-06 79 419 "NDRG2,AXIN2,ADORA2A,INTS2,SRPX,ZNF687,APC,SEMA4G,RUNX1T1,CDO1,CHN1,C7orf61,FAM189A2,MAGED1,ABI3BP,TBPL1,CNRIP1,AKAP12,VCAN,PDE4DIP,DCAF4,BOC,ARHGAP24,DAPK1,HEPH,TIAM2,RCAN1,GOLT1B,EDNRA,PLXNC1,EIF4G2,PCOLCE2,STARD3NL,LRRC17,RASGRP2,MTSS1L,RABEPK,ETV1,RASL12,ARMCX1,TUBA1B,FGFR3,TRAF3IP2,C15orf41,GSN,GSTM5,IDH3A,IDH3B,INPP5B,NCOA7,MAPT,MATN2,MEF2C,MOV10,MYO6,NRCAM,ZNF655,ZFYVE21,POLG,BCAS3,FAT4,ZCWPW1,DPF2,ROBO1,ROBO2,ELP2,RYR3,ATXN7,SCP2,PUF60,ABLIM3,FAM214B,TET1,PDLIM2,PCDHA1,CHST8,ANKRD24,ADAMTS9,ST7" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.78E-08 3.78E-04 6.91E-07 6.27E-06 40 160 "METAP1D,ADCY8,USP31,AMPH,VAT1L,BMP7,CACNA2D1,CACNB4,COL9A1,RBM39,CRYM,SNCAIP,RAB39B,DYNC1I1,TMEM35A,EYA1,ST3GAL6,FGF1,SCARA3,MEGF10,GABRB3,FAM19A2,FAM107A,HAS2,FRMD3,NEGR1,CNTN3,PRTG,KANSL1,GAL3ST4,ROBO2,SALL1,MAPK12,ZFP2,HSPA4L,ANKRD6,SLC12A2,NEK4,ERCC6L2,TPM2" Coexpression Atlas GSM538249_500 "Myeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3" "Immgen.org, GSE15907" 7.94E-08 3.86E-04 7.05E-07 6.39E-06 75 391 "PTCHD1,ALCAM,FGD2,CASK,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,USP6NL,CYBB,DOCK4,MYADM,CDON,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,GATM,GCNT2,MALT1,RAB30,ADAP1,ZNF496,GSN,FRMD5,LRRC25,IL6R,ITGAM,JAK2,KCNJ16,KIT,ASPRV1,ADAM11,ADAM22,LINC00672,MYO5A,PFKFB3,ABCB1,PLTP,RASGEF1B,PTK2,TMEM231,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,MYCBP2,RGL1,SULF2,ADGRL3,CYB561A3,SLC44A1,TNS1,NPL,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_RNAseq_e15.5_Podocytes_2500 gudmap_RNAseq_e15.5_Podocytes_2500 Gudmap RNAseq 8.09E-08 3.93E-04 7.17E-07 6.50E-06 261 1863 "EMILIN3,TMCC3,ADORA1,ADORA2A,SORCS2,C1QTNF1,ADGRF5,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PITPNM2,AMPH,PI16,MYH7B,EPB41L5,GAS7,APLP1,APOC1,CPNE5,IGDCC4,ARRB1,CADPS,MARK4,PTCH2,ADAM15,ADGRB2,NRP2,CFLAR,KSR1,SYNJ1,ST3GAL5,MYRF,IL33,LDLRAD4,CA8,CALB1,THSD7A,LDB2,CD38,ENTPD2,CACNA2D2,CHGB,CHN2,ARHGAP22,NRXN3,PPT2,FAM189A2,TMEM184B,HOMER3,CNTFR,COL4A5,COL9A1,CNRIP1,CDC42BPB,AKAP12,CRMP1,ABCG1,CRYM,SNCAIP,CSF1,CST3,PLCXD3,CYBB,DOCK4,MYADM,KIF26A,SPOCK2,BRINP1,ELMO1,SNAP91,FAM107B,SHANK1,FAM78B,MAMLD1,SEZ6L2,TSPAN5,EDNRB,HEYL,TMTC1,OPTN,RASA4,CERCAM,CALCRL,EIF1,EMX2,LRRC17,STX2,ERBB4,ERCC2,NCALD,SPEG,MRVI1,HSPA12B,REEP2,F8,FAM198B,CORO2B,ST3GAL6,CHST15,FCGRT,OLFM1,BAIAP2,SCARA3,FLNC,FLT1,AFF2,POMT1,HVCN1,ST6GALNAC3,NSG1,MEGF11,SYT17,GATM,IGSF5,SESN1,FREM1,CSDC2,GGTA1P,GGT5,LYVE1,NTNG2,LOXL3,FERMT2,GPR12,STON1,RNF165,GSTT2,LINGO1,GUCY1A1,GUCY1B1,FAM222A,MUM1,INSYN1,ACOT7,NEGR1,SHISAL1,IGF1,NKD1,IL6ST,ITPKB,KCNH2,KCNK3,TTYH2,LMO2,MAPT,MATN2,TM6SF1,MEF2C,MEIS1,MEST,KITLG,MMP17,MOV10,LAYN,MYO6,MYO7A,NEXMIF,NFIX,NME4,VWA2,NPY,NOVA2,NRCAM,NTRK2,CLDN11,CDK18,PDE3A,ENPP2,SEMA5B,RETREG1,PLEC,FXYD1,PLTP,PMP22,SEPT4,FA2H,PPARA,NKAIN4,MASP1,SNRK,PTPRB,PTPRO,PTX3,RIPOR1,TMEM255A,SH3TC2,C1orf54,SUSD4,RET,KCTD17,LGI2,ROBO2,GLDN,EMID1,SALL1,MAPK12,PRCD,PEAR1,COPZ1,RASA3,SGK1,SHMT2,ST6GAL1,NLGN1,ST8SIA1,LIMS2,SLC8A1,LIMCH1,CABCOCO1,ANKFN1,KDM4B,FAM219A,PDZD2,ARHGAP26,LHPP,CLSTN2,SAMSN1,THSD1,SST,NKAIN2,RGL1,STAC2,KANK1,STXBP1,PLCB1,TMEM150C,ARC,SYP,TACC1,TAL1,PDLIM2,KLHL4,TNS2,TEK,ZFPM2,CHST8,GALNT17,ENHO,TMEM9,HEY1,NPL,LRRC24,HSPBP1,UBC,RPRM,FLRT2,PLEKHH2,KCNT2,ATP6V0E2,REEP1,GDPD5,ADAMTS9,TMEM178A,CIAPIN1,NAV3,PCBP4,PLD4,MSRB3,DPF3" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500 Gudmap RNAseq 8.16E-08 3.96E-04 7.22E-07 6.54E-06 199 1349 "ABCF1,AXIN2,PLEKHH1,KIAA1324,MYH7B,EPB41L5,UPRT,VAT1L,BCAS1,CPNE5,ARHGDIG,KIF1A,DOCK11,BACH1,ADGRB2,BCHE,NRP2,BLM,ZNF599,PROM1,FUBP1,WASF1,CA4,CA12,PTBP2,CAMK2A,CCNT1,CDH2,ARHGAP22,NRXN3,FAM19A5,C4orf33,QKI,CNTFR,IQCK,BAG4,IGDCC3,NECTIN3,SLC35F1,FAM171B,CRMP1,LRRC3B,FAM169A,PPP1R16B,CTH,GREB1,KATNAL2,RASSF2,DDX46,SHANK1,CASP8AP2,E2F5,AASDH,EDN1,EIF5,PLEKHA1,CERCAM,EPHB1,ADGRV1,CD320,REEP2,TBC1D16,CORO2B,ST3GAL6,CEP78,PRMT5,POLR1B,SPSB4,FGF12,BAIAP2,FHL1,ZMYND15,NOP56,COQ5,CINP,SMC2,FAM49B,USP21,PRELID3A,FUT9,MTHFD2,GATM,RUNDC3A,TCERG1,DBF4,GLI2,TOX3,CBX1,KIAA1958,KDM2B,CCDC184,LPAR4,STMN2,RNF165,PSIP1,FAM222A,TOX2,FRMD5,HSF2,SHISAL1,NKD1,LRRCC1,SLC35G1,KIF2A,IPO5,KTN1,CAMK2N2,HECTD2,MAP6,MAT2A,AQP11,ADAM11,AFF1,MN1,SAMD5,MSI1,MYCN,CNOT4,NOVA2,PCBP3,NRCAM,NTRK3,PDCD2,ENPP2,FAM98B,OLA1,NLGN3,SEMA5B,PKM,SLC25A23,PLTP,PSAT1,POLR2F,PPP1R1A,MAPK4,PRODH,RELN,LAMA1,GDPD2,ELOVL2,SPDL1,PTN,PTPN13,EML5,NKAIN1,CCDC40,ERI2,FIGN,NUDT11,RPL15,RTN1,SALL1,SCN8A,TNFRSF19,ZFP2,HSPA4L,PPM1E,FHOD3,CCDC92,ANKRD6,NUBPL,PKNOX2,ANKFN1,SOX11,ZNF423,ZC3H13,RBM26,PBLD,LARP4,MTCL1,MCF2L,WSCD1,SIRT1,C18orf54,ITGB3BP,BEX4,NPL,CA14,TST,RPRM,USP1,XPO1,CFAP298,KCNT2,ZFP41,ZNF184,DPYSL5,SMARCAD1,MEIS3,SLC38A1,TUBA1A,PCBP4,WNK3,AMN1,FZD3,MRPL47,AAAS,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K5 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 8.41E-08 4.09E-04 7.43E-07 6.73E-06 28 92 "ABR,ATP1A3,HAP1,SRSF11,NRXN3,DTNA,ADGRV1,TUBB3,GAD1,SRRM4,RUNDC3A,RNF165,FAM222A,TOX2,FRMD5,MBP,SHC3,MYT1,NNAT,PLXNB1,MAPK10,RTN1,MAST1,SNAP25,SYP,MCF2L,UCHL1,DPYSL5" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.46E-08 4.11E-04 7.44E-07 6.75E-06 17 39 "SYT13,VAT1L,ARHGEF7,SEPT7,CHGB,ARHGAP32,SEZ6L2,STMN2,CELF5,LSAMP,TMOD2,PPP2R2B,SNAP25,PEG10,SEPT3,VGF,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.46E-08 4.11E-04 7.44E-07 6.75E-06 17 39 "SYT13,ANK2,CHGB,TMEM35A,RCAN2,NSG1,GNG4,STMN2,CELF5,BEX5,PCSK1,PPP2R2B,PTPRN,RTN1,SNAP25,VGF,CELF4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.52E-08 4.14E-04 7.48E-07 6.78E-06 67 336 "NDRG2,SORCS2,ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,ISPD,ARHGEF25,CBLN1,SLIT2,NRXN3,CNTFR,SNCAIP,VCAN,MYADM,RIPOR2,ARHGAP24,ARMCX2,HEPH,DNM1,EDNRA,HEYL,EGFR,EPB41L2,LRRC17,DLC1,FLNC,SEPT9,GFRA2,FREM1,CSDC2,GHR,GLI2,PRDM5,GUCY1A1,GUCY1B1,LAMA2,CHIC1,MMP16,ZC3H12B,NFIX,PCDH9,PDE3A,FXYD1,PLTP,SH3KBP1,LRRN3,LAMA1,PTCH1,PTN,ROBO2,ARMH4,ZNF354C,SATB1,LRFN5,SCN7A,PKNOX2,SLC8A1,ARFGAP1,ZNF423,SULF2,PJA1,TPM1,SSBP2,STOX2,ST8SIA2" Coexpression Atlas GSM399400_500 "alpha beta T cells, T.DPsm.Th, 4+ 8+ TCR-/lo FSClo, Thymus, avg-3" "Immgen.org, GSE15907" 8.64E-08 4.19E-04 7.57E-07 6.86E-06 68 343 "FMNL2,ADCY6,RNF157,PITPNM2,SEMA7A,ARNTL,RASL11B,ALDH7A1,BACH1,LDLRAD4,CAPN3,RCBTB2,CNN3,WHRN,AKAP12,LRIG1,CSNK1E,LONRF1,DGKG,DAPK1,NYAP1,USP3,ABCC5,RASGRP1,PAN3,USPL1,EPB41,SLC43A2,IP6K2,OGA,GPR162,DCLK2,TDRKH,MAP4K5,NIM1K,KCNH2,LIG4,AQP11,AFF1,XRRA1,ZC3H12B,PDE4D,XRN1,PLCL1,SLC25A23,SH3KBP1,POU6F1,VPS13C,RIPOR1,CEP97,ZDHHC14,PCMTD2,SATB1,DZIP1,ST8SIA1,ANKRD6,SLA,TET1,SMARCA4,KDM3A,MPRIP,ANKRD28,SLC37A2,TCF12,PRRT1,TNS1,SSBP2,NHSL1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.84E-08 4.29E-04 7.73E-07 7.01E-06 30 103 "PCDH10,INSYN2B,RNF182,CH25H,RUNX1T1,CBLN1,DCLK1,CDO1,CRLF1,ZNF521,PITPNC1,DLX1,TENM1,TMEM132C,FOXF2,NBEA,MEGF10,IFI16,NLGN3,EPB41L4B,FIGN,ZFHX4,ROBO1,SALL1,CSRNP3,ANKRD6,KLHL7,PCDHB15,PCDHB3,ASXL3" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000 kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.86E-08 4.30E-04 7.73E-07 7.01E-06 43 179 "NDRG2,SPARCL1,ALDH7A1,MYOM1,CACNA2D1,DCLK1,NDST3,ARHGEF6,RGS6,DGKB,DMD,EBF1,EDIL3,EDNRA,HEYL,FRY,RCAN2,DLC1,FHL1,TUBA8,GNAO1,GUCY1A1,GUCY1B1,TCEAL6,HSPA1L,SLC6A17,MEF2C,PDE3A,ABCB1,SERPINI1,PLCL1,FXYD1,SEPT4,RELN,FIGN,STUM,SLC4A3,SLC8A1,SLC12A2,CPEB4,TNS1,TPM2,RGS7BP" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 8.92E-08 4.33E-04 7.78E-07 7.05E-06 47 204 "ABCF1,KIAA1324,TAOK1,EPB41L5,ZNF599,PROM1,CNTFR,IGDCC3,FAM169A,KATNAL2,JAKMIP2,DDX46,PLXNC1,CERCAM,ACSL4,FGF12,FHL1,FUT9,TCERG1,MAP7D2,PCLO,CIT,SOX21,USP51,LRRTM1,KIT,KTN1,TM6SF1,NOVA1,NTRK2,FAM98B,SEMA5B,SLC25A23,ELOVL2,EML5,CCDC40,KIF21A,FHOD3,BDP1,LMO3,NEK4,SYN1,ANKRD28,ZNF106,RBFOX3,KCNT2,FXR1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_250 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_250 FaceBase_ST1 9.07E-08 4.40E-04 7.89E-07 7.16E-06 42 173 "ACADM,PCDH19,TAOK1,ABCD2,APBA2,LHX2,RAB33A,CNTNAP2,SCRN1,JAKMIP2,DLX1,EFCAB2,KIAA1841,UBE2QL1,USP51,INSM1,LRRTM1,LYRM9,MYO9A,NELL2,NOVA1,PAX6,SLC10A4,SCHIP1,MINDY2,PKIA,GDPD1,PTX3,TUG1,PBRM1,HSPA4L,KIF21A,SLC4A3,TET1,SLC35G2,CCDC173,NR2E1,XRCC4,STOX2,PARP11,AMN1,NETO2" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_200 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.33E-08 4.53E-04 8.09E-07 7.33E-06 40 161 "LCORL,BACH1,CALB1,RUNX1T1,CBLN1,SLIT2,COL9A1,RBM39,CRMP1,PUM1,TCAF1,EDIL3,MEX3B,SMC2,LPAR4,FAM19A2,INSM1,CHIC1,MEIS2,MMP16,NEFM,PCDH8,GPR85,RGS4,ZFHX4,TMLHE,MEG3,CSRNP3,ARX,CPEB4,SNAP25,RBM26,KLHL4,CBX5,ASXL3,TPM1,SSBP2,ZIC1,ADAMTS9,GAN" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k4 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.33E-08 4.53E-04 8.09E-07 7.33E-06 40 161 "RNF157,FAM135A,CASK,KALRN,CDH2,RCBTB2,ZNF521,ZFP28,NSL1,PPP1R16B,SPOCK2,BRINP1,SNAP91,EDN3,GABBR1,CHL1,FREM1,BRD8,RNFT2,TOX2,LSAMP,MEIS2,EPB41L4B,CEP41,FAT4,GAL3ST4,ZMAT4,TSPY26P,FIGN,SLC25A36,HUNK,CSRNP3,PKNOX2,ZNF334,CLSTN2,STXBP1,ASXL3,TPM2,XPO1,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.51E-08 4.62E-04 8.23E-07 7.46E-06 79 421 "EMILIN3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,CDH2,SLIT2,AKAP5,PREPL,NCOR1,VCAN,DZIP3,TM9SF4,PDCD6IP,EDIL3,EDNRB,HIPK3,SEMA3D,EIF4G1,DCTN4,EPHB1,ETV1,MRVI1,DLC1,FOXF2,SMC2,PDLIM5,CAMKK2,MEGF10,GABRA3,CHL1,PCDH17,LYVE1,RAB40B,FERMT2,RASSF8,HAS2,IFI16,RBPJ,IL6ST,LIMS1,CHIC1,MKLN1,MMP16,SAMD5,NFIX,PCDH8,PDE3A,PDE4B,RGS4,ZFHX4,TRA2B,PREX2,SLC14A1,CPEB4,PEG10,COBL,MTCL1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,ZFPM2,ERCC6L2,RGMB,SYNPO2,TRPS1,WRN,FAM13C,ACTR3B,MSRB3,NETO1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.02E-07 4.95E-04 8.81E-07 7.99E-06 23 67 "TMCC3,PCDH10,SYT13,SCAPER,RUNX1T1,NRXN3,KIAA0408,SNAP91,FGF13,NSG1,STMN2,TOX2,SHISA6,LSAMP,PDZRN4,MEG3,RTN1,SEMA6D,CLASP2,UCHL1,CELF4,REEP1,NETO2" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Subtype Migrating Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Subtype Migrating Myofibroblast Lungmap CCHMC 1.04E-07 5.05E-04 8.97E-07 8.13E-06 80 429 "CLK4,ACTN1,WDR35,C1QTNF1,FAM135A,ANK2,EP400,TNRC6C,RGS20,EIF4G3,ATP1B3,MPDZ,MAGI1,NOG,NRXN3,CSNK1E,GREB1,GPSM1,SNAP91,USP3,CD99L2,FIS1,GOLT1B,CALCRL,COQ7,AMOTL2,POLK,TMEM175,FAM49B,USP21,CAMKK2,ATP6V1H,MSANTD4,GHR,PRDM5,ZHX1,GABARAPL2,CPT1C,IDH3A,KCNN2,LAMA2,PAXBP1,ZFYVE27,MARK1,NBL1,NPR2,PGAM2,CCSER2,PKM,PMP22,STRN3,PPARA,KANSL1,NDUFS7,BCAS3,PTH1R,TMEM231,C1orf54,MEG3,FNDC3A,DZIP1,SIRT2,TRIM67,TET1,IFT122,ERC1,SS18,PHLDB1,STX1A,PLCB1,TIMP4,BHLHB9,TRIO,ZKSCAN5,VSNL1,INTS3,TUBA1A,FZD3,RSPRY1,MSRB3" Coexpression Atlas PCBC_ratio_SC_vs_DE_cfr-2X-p05 Pluripotent Stem Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.07E-07 5.18E-04 9.19E-07 8.33E-06 78 415 "TMEM132B,RNF157,VAT1L,ATP1A3,ADAM15,PROM1,CLDN10,LARGE1,CDO1,UBE2L6,PCYT1B,CRYM,VCAN,RIMS4,FAM131B,BRINP1,JAKMIP2,ALKBH8,SACS,CHRDL1,DPYSL2,AASS,PIPOX,ACSL4,PPP1R1B,ZNF589,OLFM1,FGFR1,FHL1,SEMA4D,FLT1,NSG1,MEGF10,IQGAP2,GCNT2,GLI2,GNG4,SOX21,LINGO1,CPT1C,ICA1,ZIC5,KCNN2,KIF5A,SCAMP5,MID1,MMP17,MYCN,NEFM,NELL2,NPTX2,OCRL,PCDH18,EPB41L4B,PPM1B,PPP2R2B,PRODH,GDPD2,PTN,NKAIN1,PRRT2,SLC6A8,PDZRN3,TRERF1,UNC5B,SEPT3,STXBP1,RHBDL3,ARHGEF9,SYT1,COBL,PJA1,FBXW11,WSCD1,RELL2,VSNL1,TCEAL7,GAL3ST3" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.08E-07 5.23E-04 9.25E-07 8.39E-06 67 338 "RNF157,WDR35,ARHGAP20,CASK,MPDZ,CACNA1G,MYRF,CACNA2D1,KALRN,CBLN1,LARGE1,SLIT2,CNTFR,CLIP3,VCAN,HEPH,ALKBH8,DNM1,TSPAN5,EDNRA,SEMA3D,LRRC17,FGFR1,MEX3B,FLNC,ST6GALNAC3,NSG1,DENND2A,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,TCEAL6,NKD1,MATN2,MEIS1,MEIS2,MMP16,NEFM,NNAT,NME4,PDE3A,PIK3R1,PCDH18,SH3KBP1,LAMA1,PTN,ZIK1,PTPRD,PTX3,ROBO2,ZNF354C,SATB1,ZNF821,DZIP1,PKNOX2,ARFGAP1,SULF2,SEPT3,KLHL7,ASXL3,TPM1,STXBP4,TRPS1,PLEKHH2,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k4 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.13E-07 5.49E-04 9.71E-07 8.80E-06 63 311 "PCDH19,TRMT9B,AMPH,VAT1L,DYNLL1,EIF4G3,BLM,CACNA2D1,CALB1,KALRN,CDH2,CHGB,ZFP28,NSL1,CRMP1,CRYM,SNCAIP,RIMS2,SCRN1,BRINP1,PITPNC1,RAB39B,DUSP9,HEYL,EEF1D,EYA1,MED12L,SPSB4,SCARA3,TRIM16,RASL10A,DENND2A,BRD8,KIAA1958,ADGRA3,FAM19A2,HAS2,DHX35,LIG4,NPTX1,OXTR,CNTN3,PCDH8,PRTG,PDE1C,CEP41,PPP2R3C,GAL3ST4,CRTAC1,EMID1,SALL1,ANKRD6,SLC9A5,ANKRD28,CAMTA1,ZFP90,HEY1,TP53BP1,STXBP4,ZNF184,INTS3,MRPL47,NETO2" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K5 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.15E-07 5.58E-04 9.84E-07 8.92E-06 20 53 "HAP1,SRSF11,NRXN3,DTNA,ADGRV1,TUBB3,GAD1,SRRM4,FAM222A,TOX2,IGFBPL1,KCNH2,MBP,MSI1,NNAT,NRCAM,GAL3ST4,DPYSL5,FZD3,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.15E-07 5.59E-04 9.85E-07 8.93E-06 102 591 "EMILIN3,RTL9,OSBPL8,SEMA6A,CDK10,IGDCC4,RASL11B,BMPR1B,CACNA1G,CACNA2D1,RUNX1T1,LRBA,CRLF1,DIS3L,COL9A1,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,BOC,ARHGAP24,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,DUSP9,MBNL2,LRRC17,DENND4A,HSPA12B,FCGRT,FECH,SCARA3,FOXF2,TRIM16,TRAF3IP2,ZNF274,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,SYNPO,IDH3B,INPP1,ITPKB,JAK2,LAMA2,LAMP2,SMAD9,MAN2A2,SRSF12,KITLG,FXYD7,NFIX,NPY,ZNF827,PDE3A,PDE4D,PFKFB2,SDK2,EPB41L4B,CCDC144B,CNTLN,IQSEC3,FAT4,BEND5,ZFHX4,BAALC,SH3GL3,CNKSR2,DZIP1,SLC8A1,IFT122,LIMCH1,PDZRN3,CDK19,ARHGEF9,PLCB1,TACR1,ANKRD12,TCF4,SATB2,SYNE1,PHF24,HIF3A,ASXL3,ANKRD24,PIK3R5,SYNPO2,TRPS1,TSPAN11,WIPF1,CLIP2,ZNF32,FTSJ1,ADAMTS10" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500_K1 gudmap_RNAseq_p2_CD2APMEISWT_2500_K1 Gudmap RNAseq 1.16E-07 5.65E-04 9.94E-07 9.01E-06 136 851 "ACADM,AS3MT,C3orf14,ADORA2A,ESYT2,PI16,MAP4K3,APBB2,FAM131A,ARNTL,MARK4,ATP1A1,ATP1B3,ATP6V1G2,CFLAR,KSR1,ST3GAL5,RAB29,LDLRAD4,CACNA1A,CAST,ARHGEF25,LRRFIP1,CHN1,PPT2,STOML1,CLTB,QKI,TMEM184B,AKAP7,CABP1,CLOCK,ANKRD44,ABCG1,CSF1,SOCS5,USP6NL,HDAC9,MYADM,RIPOR2,IP6K1,PITPNC1,RUSC2,DMPK,MAMLD1,FIS1,TSPAN5,TMTC1,GOLGA7,IRAK4,CALCRL,EPB41L2,EPHB1,NCALD,TAOK3,DLC1,VTI1B,CAMKK2,SARAF,ERAP1,NTNG2,FUT10,SERP2,ATE1,COQ10A,IRAK3,RASSF8,GABARAPL2,LRRC75A,ITPKB,JAK2,KIFC3,LAMP2,CAMK2N2,LIFR,MAN2A2,MBNL1,MEF2C,LAYN,IDNK,NTRK3,OGG1,PDE4A,CCSER2,PKD1,SH3KBP1,SNRK,TMEM104,PTPRB,PTPRG,ZSCAN2,C1orf54,RASGRF2,RGS3,PTGR2,MAPK12,GALNT10,RASA3,SGK1,SH3BP2,EPN2,LIMS2,SLC12A4,ELMO2,ABTB1,LMBRD1,FAM219A,ARHGAP26,SPTAN1,IQSEC2,CDK19,CAMTA2,ST5,MPRIP,SEPT8,STXBP1,TACC1,ADGRL3,TBCEL,SYNE1,CYB561A3,TEK,CHST8,THRA,ENHO,NACC2,TK2,TPM2,UBC,UBE2H,TOM1L2,CLIP2,NPDC1,ZFAND5,ITM2C,PLSCR4" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K3 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.19E-07 5.76E-04 1.01E-06 9.16E-06 99 569 "EMILIN3,HECW2,RTL9,SEMA6A,KCNAB2,CDK10,IGDCC4,RASL11B,BMPR1B,CACNA1G,CACNA2D1,RUNX1T1,CRLF1,DIS3L,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,BOC,ARHGAP24,RHOBTB1,GRIN3A,DNM1,USP3,MBNL2,EPB41,LRRC17,DENND4A,HSPA12B,FDFT1,FECH,SCARA3,FOXF2,TRIM16,TVP23A,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,SYNPO,AGBL5,INPP1,ITPKB,JAK2,LAMA2,LAMP2,SMAD9,MAN2A2,SRSF12,MSR1,FXYD7,NFIX,ZNF827,PDE3A,PDE4D,PFKFB2,EPB41L4B,CCDC144B,CNTLN,IQSEC3,FAT4,BEND5,RBBP8,ZFHX4,MRAP2,BAALC,SH3GL3,CNKSR2,DZIP1,SLC8A1,PDZRN3,DOP1A,CDK19,ARHGEF9,PLCB1,TACR1,ANKRD12,TCF4,SATB2,SYNE1,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRO,TRPS1,TSPAN11,WIPF1,ZNF32,NAV3,ADAMTS10,KLHDC1,FRMD6" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.22E-07 5.92E-04 1.04E-06 9.39E-06 47 206 "GALNT13,RNF150,C1QTNF3,ALCAM,ABCD2,DPP10,DOCK11,IL33,THSD7A,RUNX1T1,LDB2,NCOR1,LRIG1,RASSF2,EBF1,EDIL3,EDN3,SEMA3D,TMTC1,SLC37A3,IQGAP2,GGT5,GPR12,GUCY1B1,RASSF8,MSL1,IFI16,KCND2,NOVA1,PDE4B,GPR85,PLCL1,SH3KBP1,RELN,FAT4,KIRREL1,CCDC112,CSRNP3,SCN7A,ST8SIA1,ITPRID2,ADGRL3,PCDHB9,TRO,SSBP2,PCDH20,LYPD6" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_1000 kidney_P2_CapMes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.25E-07 6.07E-04 1.06E-06 9.61E-06 108 637 "ABR,NDRG2,RNF157,MTUS1,TXNDC16,ALCAM,CEP126,AMPH,VAT1L,ADAM23,BARD1,BCHE,BCL7A,BMP7,IL33,CA12,CACNA2D1,CACNB4,CDH2,CHRNA4,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,BOC,TM9SF4,SPOCK2,GSDME,SNAP91,SV2B,ARRDC4,DTNA,EDNRA,HEYL,C8orf37,ETV1,EXTL2,EYA1,ST3GAL6,FCGRT,SLC9B2,FGF1,FGFR1,MAD2L2,SCARA3,WDR83,TMEM107,STAU2,MTHFD2,IGSF5,GFRA2,FREM1,TDRKH,CNTRL,GRIK4,FAM107A,HAS2,NEGR1,HSPA1L,KHK,MAT2A,MEIS2,MEST,POC1B,MMP16,MSI1,NFIX,NME4,NPY,CNTN3,PRTG,ENPP2,SMOX,PPP1R1A,EPDR1,ELOVL2,SPDL1,PTN,ZCWPW1,RBBP6,TSPY26P,NUDT11,ROBO2,HUNK,ZNF354C,SALL1,SLC4A3,SLC12A2,GKAP1,LIMCH1,CMTR2,SULF2,NUDT10,CAMTA1,CUX2,TRIM2,PCDHB9,PCDHB3,HEY1,TPM2,NDRG4,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.26E-07 6.11E-04 1.07E-06 9.66E-06 29 99 "ATP1A3,HAP1,SRSF11,LHX2,NRXN3,IGDCC3,SCRN1,DLX1,ADGRV1,TUBB3,GAD1,SRRM4,RUNDC3A,STMN2,RNF165,SOX21,TOX2,IGFBPL1,SHC3,MYT1,NNAT,NRCAM,HSPA4L,KIF21A,ARX,NR2E1,WNT7A,ZIC1,DPYSL5" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k3_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.29E-07 6.28E-04 1.09E-06 9.92E-06 99 570 "CCDC85A,ADORA2A,HECW2,ADGRF5,MAP4K3,APBB2,SHROOM2,ARRB1,DOCK11,ADAM15,NRP2,PROM1,ARHGEF7,LDLRAD4,THSD7A,CALM1,SCARB1,CD38,ARHGEF2,LRRFIP1,MS4A7,TAOK2,ABCG2,TMEM184B,MAP4K4,LY86,CDC42BPB,CRMP1,HAPLN1,CSF1R,USP6NL,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,SACS,FAM107B,ECM2,EBF1,EDNRB,CALCRL,RASGRP2,STX2,DENND4A,CORO2B,FLT1,PDLIM5,TRIM16,FYB1,INPP5K,PCDH17,GGTA1P,HPGDS,GLUL,LILRB4,LPAR4,STMN2,GRIA2,MAP4K5,NCKAP1L,ICA1,LMO2,TM6SF1,MEF2C,MYO6,PDE4B,PDE4D,ABCB1,PLCL1,DRAM2,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,KCTD17,SGK1,PREX2,BTBD3,CPEB4,LIMCH1,UNC5B,SAMSN1,THSD1,PLCB1,KLHL4,TEK,HEY1,TLR4,WIPF1,GDPD5,NAV3,FAM13C,DOCK8,JMJD1C,MSRB3,ZDHHC20,SPATA13" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_500 kidney_P2_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.34E-07 6.49E-04 1.13E-06 1.02E-05 60 292 "ABR,RNF157,MTUS1,ALCAM,AMPH,VAT1L,ADAM23,BARD1,BCHE,BCL7A,BMP7,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CRYM,SNCAIP,VCAN,CTH,SPOCK2,GSDME,SNAP91,DTNA,EDNRA,HEYL,ETV1,EYA1,ST3GAL6,FGFR1,SCARA3,TMEM107,STAU2,MTHFD2,IGSF5,FREM1,TDRKH,FAM107A,HAS2,NEGR1,MEIS2,NME4,NPY,CNTN3,TSPY26P,ROBO2,SALL1,SLC4A3,SLC12A2,NUDT10,CUX2,TRIM2,PCDHB9,HEY1,TPM2,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Proliferative Myofibroblast Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Proliferative Myofibroblast Lungmap CCHMC 1.36E-07 6.59E-04 1.14E-06 1.04E-05 82 446 "FMNL2,ANK2,LCORL,CASK,RASL11B,ZNF583,ALDH7A1,DST,RUNX1T1,NFS1,CBFA2T2,LRRFIP1,MAGI1,COPB2,CHN2,TBPL1,SNCAIP,SEC24C,GPSM1,DCAF8,MATR3,FAM107B,CD99L2,EDNRB,TNK2,CALCRL,FOXF2,SEPT9,CSDC2,GHR,DBF4,GPT2,ADAMTS6,GUCY1B1,HLF,IDH3B,IGF1,KCNK3,IPO5,TTYH2,LAMA2,NCOA7,SAMD5,NNAT,GNG2,PPP3CA,PTCH1,PTH1R,SPDL1,ROGDI,RDX,REV3L,UBR7,RNH1,ROBO1,ROBO2,CCDC112,FAM192A,TNFRSF19,PUF60,DZIP1,NUBPL,WDR37,EPC1,SMARCC2,CDK5RAP2,PDZRN3,SOX11,ZC4H2,BEX4,TP53BP1,TPM2,SYNPO2,AMACR,STXBP4,VSNL1,TSPAN11,ZNF32,ZNF184,EVI5,TUBA1A,ADAMTS10" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.43E-07 6.95E-04 1.21E-06 1.09E-05 19 49 "DPP10,VAT1L,CHGB,CNR1,CNTN1,AKAP6,MYRIP,STMN2,FAM19A2,INSM1,MAP4,NEFM,NTRK2,NALCN,MAPK10,PRPH,RET,RGS4,SNAP25" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_1000 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.75E-07 8.49E-04 1.47E-06 1.33E-05 142 904 "ASPHD1,ACHE,GALNT16,RNF157,MTUS1,LTBP4,C6orf89,APLP1,VAT1L,CPNE5,ARHGDIG,CADPS,CHID1,KIF1A,ADAM23,ADGRB3,NRP2,CACNA1G,RUNX1T1,DCLK1,LARGE1,CHGB,RAB33A,CLTB,PICK1,CNTFR,FAM171B,CRMP1,CLIP3,VCAN,PLXNA4,SCRN1,BRINP1,B3GAT3,GRIN3A,DNM1,DPP6,FIS1,EBF1,EDNRA,EDNRB,LRRC17,ERBB2,SPEG,EYA1,TUBA1B,TUBB3,FCGRT,FDFT1,FGF13,FLNC,TMEM107,ERGIC3,NSG1,TPPP3,TVP23A,FYB1,SYT17,IGSF5,GFRA2,FREM1,GLI2,KCNMB4,GNAO1,GP1BB,STMN2,GRIA2,GSTM5,ACOT7,DISP2,L1CAM,LMO2,SYTL4,LSAMP,MAP6,MATN2,MEIS1,MMP16,COMMD5,ADAM22,TAGLN3,MYH3,IDNK,NEFM,NELL2,NFIX,NNAT,NME4,NPY,NOVA1,NPR2,PCBP3,NTRK2,NTRK3,CLDN11,SLC10A4,PGAM2,SMOX,FXYD1,PCDH18,PLTP,PMP22,POLR2F,NKAIN4,MAPK10,PRPH,MASP1,NDUFS7,EML5,TMEM255A,FAT4,TSPY26P,RET,ROBO2,ARMH4,HUNK,RTN1,S100B,SNAP25,SNRPN,SST,SULF2,SEPT3,NUDT10,ADAMTS17,SYP,SYT1,ASTN2,ADGRL3,CUX2,PCDHB9,THRA,TMEM9,TPM2,KCNE5,SSBP2,SLC35A4,UCHL1,MTCH1,VLDLR,ZNF32,DPYSL5" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.76E-07 8.54E-04 1.48E-06 1.34E-05 61 301 "FMNL2,KLHL13,OGT,LGR5,PPP4R4,NUMB,INSYN2B,WASF1,SLC16A4,DCLK1,MAGI1,PLXNA4,CTH,DOCK4,DAPK1,CDON,DRP2,KLHL5,TMEM35A,EMX2,NRN1,NSG1,GALC,SESN1,IL6ST,KLHL23,MAP2,KITLG,MYO9A,NEXMIF,NPR2,SERPINI1,PPP3CC,GDPD2,CNTLN,PTPRG,FAT4,REV3L,ZFHX4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ST8SIA1,SLC4A3,ATF7IP,KDM3A,UHRF1BP1L,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,ACTR6,KAT6B,DCBLD1,LYPD6,FRMD6,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.85E-07 8.96E-04 1.55E-06 1.40E-05 24 74 "NDRG3,SYT13,ANK2,ZSCAN18,CHGB,EDIL3,TMEM35A,RCAN2,NSG1,GNG4,STMN2,CELF5,MARK1,BEX5,PCSK1,PPP2R2B,VSTM2L,PTPRN,RTN1,SNAP25,PLCB1,VGF,CELF4,REEP1" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_1000 DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.87E-07 9.06E-04 1.56E-06 1.41E-05 130 811 "PLEKHH1,ADORA1,PCDH19,DOC2A,APBB2,EPB41L5,LGR5,CDC14B,ASPA,CCAR2,NRP2,PROM1,BMP7,CA4,CA12,CACNA2D1,HIP1R,CLDN10,CD38,LRBA,CACNA2D2,RBM39,LRIG1,KIAA0040,CTH,GREB1,ARHGAP24,SCRN1,AIF1L,TMCC2,DUSP9,HIPK3,HEYL,EIF5,EIF1,EMX2,EPB41,RASGRP2,EPHB1,CD320,ST3GAL6,MED12L,SPSB4,FGFR1,FOXO3,FLT1,ANKFY1,SMC2,RASL10A,CGREF1,FUT9,GALC,SYT17,IGSF5,GCNT2,PCDH17,PPARGC1A,AIFM3,CBX1,KCNMB4,ADGRA3,GPER1,GRB10,PARD3B,FAM107A,HP,SCIN,KCNJ5,KCNJ16,TTYH2,LIFR,GPR155,CLEC18A,AQP11,TM6SF1,KITLG,VWA2,NRCAM,OXTR,ENPP2,PIK3C2A,RETREG1,PLXNB1,ANKRD16,SCHIP1,MBOAT7,POLG,IRX1,KANSL1,MAPK4,RELN,CNNM2,LAMA1,ELOVL2,PTPRO,RIPOR1,NKAIN1,ZDHHC14,DPF2,EMID1,SALL1,SCN8A,HES6,ZNF821,FHOD3,FAM81A,DHX30,SLC9A5,MYCBP2,DDN,ZSCAN29,APOM,STX1A,TMEM150C,TAF9,DNMBP,WSCD1,SIN3B,SATB2,HEY1,ERCC6L2,RGMB,ELP5,DCBLD1,CA14,ZNF23,GDPD5,TMEM178A,FIP1L1,SPATA13" Coexpression Atlas BM Top 100 - substantia nigra BM Top 100 - substantia nigra Body Map 1.87E-07 9.09E-04 1.56E-06 1.42E-05 22 64 "PLEKHH1,CARNS1,VXN,SYNGR3,CDR1,MAP4K4,GPR37,STMN2,KCNJ16,MAP4,MBP,NEFM,NEFH,QDPR,TMEM255A,SPP1,SYT1,SLC44A1,PRR18,UGT8,P2RY12,CLDND1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.91E-07 9.25E-04 1.59E-06 1.44E-05 102 597 "EMILIN3,RTL9,SRPX,KCNAB2,CDK10,IGDCC4,SPTBN4,RASL11B,CACNA1G,GPC2,RUNX1T1,LRBA,CDO1,CRLF1,COL9A3,ABI3BP,ANKRD44,SNCAIP,ARHGAP24,DGKG,RHOBTB1,GRIN3A,DNM1,HEYL,MBNL2,ELN,HSD17B14,EPB41,LRRC17,DENND4A,HSPA12B,FCGRT,SCARA3,FOXF2,TRIM16,STAU2,TVP23A,ZMAT1,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,SYNPO,ICA1,LRRCC1,INPP1,JAK2,LAMA2,LAMP2,SMAD9,MAN2A2,ADAM11,SRSF12,TCEAL5,FXYD7,NFIX,NPY,ZNF827,CNTN3,PDE3A,PDE4D,PFKFB2,SDK2,EPB41L4B,CCDC144B,DIRAS2,PRODH,CNTLN,PTPRE,IQSEC3,BEND5,MORC4,ZFHX4,MRAP2,BAALC,DGLUCY,SH3GL3,CNKSR2,DZIP1,SLC8A1,SMARCC2,PDZRN3,BDP1,CDK19,NKAIN2,ARHGEF9,PLCB1,TACR1,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPS1,ZNF32,NAV3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K1 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.91E-07 9.28E-04 1.59E-06 1.44E-05 84 464 "METAP1D,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,DGKG,TIAM2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,PTK2B,DLL3,ABLIM2,FYB1,GAA,GHDC,TMEM8B,GHR,LYVE1,NTNG2,GNG4,GRIK4,GUCY1B1,ICA1,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,TCEAL5,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,PRIMA1,STK32B,LRRK2,LRFN5,MRAS,SGK1,ASAP3,ARHGAP26,IQSEC2,NKAIN2,ADGRL3,FAM189A1,LRRC24,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_500 kidney_P0_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.94E-07 9.42E-04 1.61E-06 1.46E-05 60 295 "ABR,NDRG2,RNF157,ALCAM,AMPH,VAT1L,SEMA4G,CASK,BCHE,DST,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,SPOCK2,GSDME,SNAP91,ARRDC4,DTNA,EDNRA,CALCRL,ETV1,EYA1,ST3GAL6,FGF1,FGFR1,SCARA3,IGSF5,FREM1,TDRKH,FAM107A,HAS2,NEGR1,MEIS2,MEST,MMP16,NME4,CNTN3,PRTG,SMOX,PPP1R1A,ROBO2,HUNK,SALL1,SLC4A3,SLC12A2,SULF2,NUDT10,ADAMTS17,CUX2,TPM2,LAMP5,SIGLEC10" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K4 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.98E-07 9.59E-04 1.64E-06 1.48E-05 27 90 "ATP2B2,HAP1,SLITRK5,DTNA,EPHB1,APC2,ADGRV1,REEP2,TUBB3,DLL3,SRRM4,STMN2,RNF165,TOX2,FRMD5,IGFBPL1,MAP2,NRCAM,GAL3ST4,CCDC112,HSPA4L,SEPT3,TCF4,MGAT5B,DPYSL5,FZD3,SPATA13" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500 dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.00E-07 9.71E-04 1.66E-06 1.50E-05 77 414 "FMNL2,MTA3,KLHL13,ARHGAP20,OGT,SEMA7A,LGR5,CDC14B,SEMA4G,PPP4R4,PDE8B,INSYN2B,SLC16A4,DCLK1,MAGI1,UBE2L6,AKAP5,ZNF521,PLXNA4,DOCK4,DAPK1,DOCK2,DRP2,RASGRP1,KLHL5,PLXNC1,EMX2,NRN1,AFF2,NSG1,GATM,PACSIN2,TCEAL6,IGF1,IL6ST,KCND2,KLHL23,SYTL4,MAP2,KITLG,MYO9A,NPR2,SERPINI1,PCDH18,GDPD1,GDPD2,CNTLN,FAT4,REV3L,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,CNKSR2,ST8SIA1,SLC4A3,SNCA,KDM3A,UHRF1BP1L,TSPYL2,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,OBSL1,DNAH7,ACTR6,DCBLD1,TST,ZNF23,LYPD6,REEP1,WNK3,FRMD6" Coexpression Atlas GSM854326_500 "Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3" "Immgen.org, GSE15907" 2.03E-07 9.86E-04 1.67E-06 1.52E-05 76 407 "TMCC3,ADRB2,BEND6,MTUS1,ABCD2,BIN1,FGD2,CASK,NUMB,ATP6V0A1,ADAM15,DST,ST3GAL5,SGCE,CAPN3,USP2,CD86,LARGE1,ARHGAP22,LY86,CRYBB1,CSF1R,CST3,DOCK4,RHOBTB1,RCAN1,EPB41L2,ETV1,TLR7,FCGR1A,ST3GAL6,TMEM107,KHDRBS3,GATM,HPGDS,GLUL,GPR34,LRRC25,IL6R,ITGAM,KCND1,LIFR,LMO2,GPR155,MEF2C,SCAMP5,P2RY13,NCF2,P2RX7,TREM2,SMOX,PMP22,RASGEF1B,TMEM104,ROGDI,GAL3ST4,RTN1,SALL1,MRAS,SGK1,SLC2A5,ARHGEF40,SLC11A1,SLC12A2,SLC37A2,TLR4,LRRC8A,NPL,RGMB,P2RY12,AGMO,HPS4,NAV3,ITM2C,PLD4,NLRP3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.03E-07 9.86E-04 1.67E-06 1.52E-05 43 184 "NDRG2,SPARCL1,ALCAM,ADGRB1,BMP7,CA12,PRC1,CDO1,IGDCC3,CST3,RASSF2,DBI,LYPD1,DPP6,EDNRB,EGFR,TNK2,ETV1,ADGRV1,PDLIM5,TPPP3,PCDH17,LUZP2,DCLK2,HAS2,CFAP126,NRBP2,MXI1,NFIX,NTRK2,ENPP2,SCHIP1,NKAIN4,PTN,KLHDC8A,S100B,ITPRID2,SULF2,WSCD1,ZEB1,TCF12,HEY1,CABIN1" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_1000 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000 PCBC 2.11E-07 1.02E-03 1.74E-06 1.57E-05 153 994 "ABHD6,TMCC3,SORCS2,TRMT9B,CCDC146,APLP1,LGR5,LINC00173,DNAJC27-AS1,IL33,CA4,CABP7,CAMK2A,VXN,ISPD,SLC16A4,P2RX6,CDH2,NOG,LHX2,CNTFR,AKAP6,NRG2,FAM171B,SEC31B,HAPLN1,PLCXD3,BOC,ARHGAP24,DGKG,LYPD1,KIF19,CD99L2,CDON,EDN1,YAF2,MBNL2,EGR3,EMX2,NCALD,NRN1,CLVS1,TMEM132C,PRAM1,DLC1,ATP13A4,TMEM175,TPPP3,DENND2A,IP6K3,GPR162,ADAM28,AIFM3,DCLK2,SPACA9,FAM107A,GUCY1A1,GUCY1B1,ATOH8,FAM222A,UBE2QL1,ZNF491,KIAA1755,TMEM240,INSM1,LRRTM1,NME9,ITPKB,CDH20,SYTL4,CLEC18A,MAP2,MAP6,MEIS1,MEIS2,SAMD5,NRBP2,TAGLN3,RTL5,ZNF862,NPY,IGSF11,CNTN3,PAX6,PRTG,PDE1C,ENPP2,SDK2,VSTM2L,MAPK10,RELN,LAMA1,ELOVL2,PTX3,RIPOR1,STRC,TMEM255A,PRRT2,MORC4,ZFHX4,KLHDC8A,KIRREL1,CCDC102B,BAALC,EMID1,MELTF-AS1,HSD11B1L,TNFRSF19,SMPD3,PEAR1,ARX,CCDC92,SYBU,FAM214B,PKNOX2,GKAP1,DMRTC1,SOX3,IZUMO4,LMO3,CLSTN2,SSPO,ADAMTS17,ZEB1,PCDHGB6,PCDHB10,PCDHA6,PCDHA3,DICER1-AS1,ASXL3,NR2E1,RIMBP2,DOK6,LRRC24,PPIL6,CLEC2L,TOM1L2,ZIC1,ELFN1,ZFP41,EMX2OS,CRB2,MKRN3,DPYSL5,GDPD5,ADAMTS9,NAV3,DNAH10,DOCK8,FAM182B,MSRB3,FAM181A,PRRT4" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000_k3 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.19E-07 1.06E-03 1.79E-06 1.63E-05 33 124 "PDE8B,BMPR1B,CALB1,LRBA,B4GALT6,SLIT2,FAM149A,NECTIN3,IPCEF1,MFAP3L,TENM1,EMX2,ENO2,SPSB4,C2orf88,PADI2,L1CAM,KITLG,VWA2,EML5,FAM184A,RASGRF2,RET,SCN8A,TRA2B,NUDT10,TMEM150C,CUX2,DCBLD1,RPRM,EMX2OS,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K5 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 2.19E-07 1.06E-03 1.79E-06 1.63E-05 41 172 "EMILIN3,SEMA6A,ARHGAP20,LGR5,CDK10,ADGRB2,CACNA1G,LDLRAD4,CACNA2D1,KCNAB3,CDO1,CRLF1,PCYT1B,ANKRD44,CSF1R,EBF1,ELN,LRRC17,FCGRT,TRIM16,NSG1,FYB1,TMEM8B,NTNG2,ZNF276,GSN,RASSF8,HLF,SYNPO,SRSF12,NFIX,CNTN3,PDE4D,PLCL1,TRHDE,ACSS3,ZMAT4,ADGRL3,PHF24,TSPAN11,CADM2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.21E-07 1.07E-03 1.81E-06 1.64E-05 13 25 "VAT1L,CRMP1,FGF13,NSG1,GFRA2,STMN2,L1CAM,NELL2,SLC10A4,RET,RGS4,SYT1,UCHL1" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_500 dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.21E-07 1.08E-03 1.81E-06 1.64E-05 77 415 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,NRP2,ARHGEF7,LDB2,CD38,MS4A7,ABCG2,TMEM184B,ZNF521,HAPLN1,CSF1R,CYBB,DOCK4,RASSF2,PITPNC1,ELMO1,ECM2,EBF1,EDIL3,EDNRB,PLEKHA1,CALCRL,RASGRP2,DENND4A,CORO2B,DLC1,FLT1,PDLIM5,FYB1,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,MAP4K5,ICA1,IGF1,ITPKB,KIT,LMO2,TM6SF1,MEF2C,KITLG,PDE4B,GNG2,PLCL1,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,PREX2,BTBD3,CPEB4,LIMCH1,UNC5B,THSD1,PLCB1,KLHL4,TCF4,TEK,HEY1,DCBLD1,WIPF1,ZNF711,NAV3,FAM13C,RNF146" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.25E-07 1.09E-03 1.83E-06 1.66E-05 76 408 "EMILIN3,ADCY5,USP31,PCDH10,DPP10,APC,TNRC6C,ADAM23,NRP2,BMP7,DST,CACNA1B,CACNA2D1,KALRN,RUNX1T1,FAM171B,ANKRD44,CLIP3,SNCAIP,SIPA1L1,VCAN,PYGO1,JAKMIP2,ELMO1,GRIN3A,DNM1,EDNRB,HIPK3,EGFR,ETV1,EYA1,TMEM132C,CORO2B,FOXF2,CHL1,IQGAP2,SYT17,GFRA2,PCDH17,KIAA1958,GRIA2,BACH2,IFI16,MKLN1,MYH3,NDP,NEFM,NFIX,CLDN11,PDE3A,GPR85,TRHDE,KANSL1,FAT4,REV3L,ZFHX4,ARMH4,RYR3,SALL1,TNFRSF19,ZHX3,ARHGEF9,MTCL1,ADGRL3,CUX2,FAM189A1,PCDHB7,TIAM1,ERCC6L2,RGMB,SYNPO2,TRPS1,RPRM,TCEAL7,MSRB3,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.28E-07 1.11E-03 1.86E-06 1.68E-05 75 401 "AXIN2,PCDH19,SEMA6A,DOC2A,FGD2,EPB41L5,PDE8B,ZNF599,BMP7,BMPR1B,CA12,CACNA1B,CALB1,CRLF1,B4GALT6,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,KIAA0040,CTH,GREB1,KATNAL2,RAB39B,DUSP9,TENM1,EMX2,ENO2,SPSB4,FGF12,SEMA4D,RASL10A,PRELID3A,GALC,MAP7D2,FAM19A2,PADI2,FRMD5,SLC35G1,KCNJ16,L1CAM,AQP11,KITLG,VWA2,NRCAM,PRTG,PFKFB3,SEMA5B,SLC25A23,PLXNB1,LAMA1,EML5,NKAIN1,CCDC40,FAM184A,RASGRF2,GAL3ST4,RET,NUDT11,EMID1,SCN2B,SCN8A,SHMT2,FHOD3,NUDT10,TMEM150C,WSCD1,DCBLD1,CA14,RPRM,VSNL1,EMX2OS,FSTL5,TMEM178A,FZD3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 2.45E-07 1.19E-03 1.99E-06 1.81E-05 24 75 "SYT13,KIF1A,GPC2,SEPT7,NSG1,GABRB3,STMN2,PTPRT,UBE2QL1,MAP6,SAMD14,MYO5A,BEX5,GNG2,RGS4,RTN1,MRAS,ARX,SNAP25,PEG10,SYP,VGF,CELF4,REEP1" Coexpression Atlas GSM605840_500 "Plasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 2.49E-07 1.21E-03 2.02E-06 1.83E-05 76 409 "ABHD6,FMNL2,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ZBTB10,ATP1A3,DDR1,CD38,STOML1,LY86,MAGED1,ZNF521,CST3,RUBCN,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,CHST15,TMEM107,HVCN1,AK8,FYN,GPR162,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,ADAM11,MEF2C,MYO5A,P2RY13,ZC3H12B,NUCB2,PGAM2,PLTP,TMEM231,ROGDI,ZDHHC14,PPM1E,ST8SIA1,BTBD3,CCDC88A,TEX2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,CYB561A3,SLC44A1,TNS1,P2RY12,LAT2,EVI5,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k1 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.54E-07 1.23E-03 2.05E-06 1.86E-05 27 91 "SPARCL1,IGDCC4,CADPS,RUNX1T1,CALCRL,GFRA2,GPT2,NEGR1,IGF1,NKD1,KCND2,MATN2,MEIS2,MMP16,FXYD7,NFIX,CLDN11,PTCH1,LGI2,TMLHE,SATB1,TROVE2,SYT1,ZFPM2,TPM1,TPM2,TUBB2A" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_200_k5 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.54E-07 1.23E-03 2.05E-06 1.86E-05 27 91 "BACH1,RUNX1T1,SLIT2,PLAA,COL4A5,ZC3H11A,EIF4G1,EPB41L2,SMC2,LPAR4,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,PCDH9,PIK3R1,C1orf54,MEG3,TRA2B,ZC3H13,CBX5,R3HDM1,SSBP2,FLRT2,GAN" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.59E-07 1.26E-03 2.09E-06 1.89E-05 18 46 "VAT1L,CADPS,SCRN1,EYA1,TUBB3,SYT17,IGSF5,GNAO1,STMN2,L1CAM,NEFM,NELL2,MAPK10,RET,RTN1,SNAP25,SYT1,CUX2" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k5_500 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.59E-07 1.26E-03 2.09E-06 1.89E-05 18 46 "APLP1,CRMP1,CSNK1E,GSDME,TUBB3,DLL3,STMN2,BACH2,INSM1,MAPT,NEFM,GNG2,ZFHX4,SNRPN,SOX11,TRIM2,ZIC1,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.59E-07 1.26E-03 2.09E-06 1.89E-05 73 388 "NDRG2,ADCY5,SPARCL1,PI16,ATP2A2,MYOM1,NRP2,CACNA2D1,CLDN10,CFL2,AKAP6,AKAP5,ABI3BP,DMPK,CPEB2,DTNA,ELN,NCALD,MRVI1,PRKAG2,FHL1,FLNC,IGSF5,GCNT2,GFRA2,RAB40B,FERMT2,PRUNE2,TPPP,BVES,HNMT,IFI16,SHISAL1,IL6ST,KCNB1,KCNF1,MBP,MMP17,NRBP2,MYH3,ALDH1L2,NPTX2,PDE4D,TMEM38A,FXYD1,SCHIP1,PRKCB,PSD,RYR3,SCN7A,STUM,SH3BGR,FHOD3,ABLIM3,LIMS2,FNBP1,DBNDD2,ARHGEF9,SYN2,ENHO,NACC2,TNS1,TPM1,TPM2,RGMB,SYNPO2,PPIL6,RBFOX3,PLSCR4,RGS7BP,FAM13C,ACTR3B,MSRB3" Coexpression Atlas Arv_SC_fibroblast_1000_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 2.64E-07 1.28E-03 2.13E-06 1.93E-05 96 556 "SYN3,TMEM132B,GALNT13,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,KIF1A,ADGRB1,HAP1,CLDN10,SYNGR3,FAM19A5,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,IGDCC3,LRRC3B,RIMS4,CNTNAP2,SEC14L5,KCTD8,BRINP1,DPP6,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,IGSF5,GNG4,LPAR4,LINGO1,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KCNN1,KIF5A,CAMK2N2,CHST6,TCEAL5,FXYD7,NELL2,NNAT,SEMA5B,JAKMIP1,EPB41L4B,PPP2R2B,GDPD2,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,HUNK,SALL1,TMEM200C,PPM1E,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,CA14,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.74E-07 1.33E-03 2.20E-06 1.99E-05 39 161 "ADORA1,PCDH19,DOC2A,BMP7,CA4,CALB1,CRLF1,CRYM,KIAA0040,GREB1,DUSP9,EMX2,EPHB1,RACK1,ST3GAL6,FKTN,SLC9B2,SPSB4,FGFR1,PSD2,RASL10A,GALC,IGSF5,ADGRA3,PRDM5,CLEC18A,MID1,NPY,OXTR,PRTG,PLXNB1,LAMA1,NKAIN1,GAL3ST4,EMID1,SALL1,HEY1,CA14,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.79E-07 1.35E-03 2.24E-06 2.03E-05 50 231 "EMILIN3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,BCHE,CACNA2D1,PREPL,VCAN,DZIP3,TM9SF4,PDCD6IP,EDNRB,HIPK3,SEMA3D,EIF4G1,DCTN4,EPHB1,ETV1,DLC1,SMC2,PDLIM5,CAMKK2,GABRA3,PCDH17,RASSF8,HAS2,RBPJ,LIMS1,CHIC1,MKLN1,MMP16,SAMD5,PDE3A,TRA2B,PREX2,CPEB4,PEG10,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,ZFPM2,ERCC6L2,RGMB,TRPS1,WRN,NETO1" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500 DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.87E-07 1.40E-03 2.30E-06 2.08E-05 73 389 "ADD1,LCORL,PKP4,LGR5,PDE8B,ASPA,INSYN2B,DOCK11,BACH1,SYNJ1,SGCE,CALB1,ZNF445,SRSF11,SLIT2,CNR1,RBM39,DZIP3,PUM1,AIF1L,ZC3H11A,SNAP91,DRP2,EDNRA,RASGRP1,PLXNC1,EIF4G1,EMX2,EPB41L2,NRN1,SCML2,MEX3B,GATM,MAP7D2,LPAR4,KCND2,CHIC1,KITLG,SAMD5,NEXMIF,CNOT4,GLIPR1L2,PDPK1,SERPINI1,SEMA5B,C1orf54,RNASEL,TMLHE,ATP8B4,MEG3,PRCD,FNIP1,TNFRSF19,ARX,SYBU,CPEB4,ZKSCAN3,ZC3H13,LARP4,SYNE2,SLC37A2,DMXL2,CBX5,NR2C2,SSBP2,UGT8,ZNF711,ZNF23,EMX2OS,REEP1,ADAMTS9,KLHDC1,SENP7" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_1000 dev gonad_e11.5_M_ReproVasc_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.12E-07 1.52E-03 2.49E-06 2.26E-05 127 795 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,APOC1,SHROOM2,ARRB2,MARK4,ATP1B3,DOCK11,ADAM15,NRP2,ARHGEF7,CA8,LDB2,CD38,ARHGEF2,MS4A7,ABCG2,TMEM184B,LY86,CNN3,ARHGEF6,ZNF521,CRMP1,HAPLN1,CSF1R,CYBB,DOCK4,RASSF2,GIT2,PITPNC1,JAKMIP2,ELMO1,FAM107B,ECM2,EBF1,EDIL3,EDN1,EDNRB,YAF2,PLEKHA1,CALCRL,RASGRP2,STX2,DENND4A,FAM198B,CORO2B,FCGR1A,FLT1,NOP56,TMEM107,UFM1,PDLIM5,TRIM16,FYB1,PCDH17,GGTA1P,LYVE1,HPGDS,GLUL,LILRB4,LPAR4,STMN2,MAP4K5,NCKAP1L,ELOVL5,ZDHHC15,ICA1,IFI16,IGF1,ITPKB,KIT,LIFR,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,MYO6,MYO9A,NEFM,NME4,PDE4B,PDE4D,GNG2,SCHIP1,PILRA,DRAM2,MAPK3,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,RGS3,SEMA6D,RASA3,SGK1,PREX2,BTBD3,CPEB4,LIMCH1,PEG10,SAMSN1,THSD1,SYNE2,KLHL4,TCF4,DOCK9,TEK,ZFPM2,C18orf54,HEY1,TLR4,C9orf85,FLRT2,WIPF1,ZNF711,NAV3,FAM13C,MRPL47,ZDHHC20,RNF146" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.16E-07 1.53E-03 2.52E-06 2.28E-05 40 168 "ADORA1,HECW2,AMH,SEMA7A,ARHGDIG,CADPS,BCHE,SYNJ2,CACNA2D2,CLTB,PPP1R16B,JAKMIP2,ELMO1,PLPPR4,RCAN1,DTNA,MAMLD1,EDN1,MRO,CERCAM,ERBB4,REEP2,PTK2B,TUBB3,FGF13,PADI2,MYO7A,CLDN11,PGAM2,SCHIP1,RASGEF1B,EPDR1,MASP1,DUSP15,SLC6A8,TACC1,SIN3B,THRA,SGK3,NHSL1" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500 DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.22E-07 1.57E-03 2.57E-06 2.33E-05 72 383 "ADD1,TAOK1,LCORL,LGR5,MADD,INSYN2B,BACH1,CALB1,PLAA,CNR1,RBM39,FAM169A,DZIP3,DOCK4,GSDME,SACS,CPEB2,RASGRP1,EIF4G1,EMX2,EPB41L2,NRN1,SCML2,MEX3B,SMC2,GATM,MAP7D2,TDRKH,LPAR4,KCND2,CHIC1,KITLG,MYO5A,NEXMIF,CNOT4,GPR137C,PDPK1,SERPINI1,C19orf57,EML5,TMLHE,MEG3,PRCD,FNIP1,TRA2B,ARX,CPEB3,SYBU,CPEB4,ZKSCAN3,ZNF667,ZC3H13,RBM26,LARP4,SYNE2,SYN2,ANKRD12,KLHL4,DMXL2,SIRT1,CBX5,ACTR6,R3HDM1,NR2C2,TSC1,SSBP2,UGT8,VSNL1,ZNF711,ADAMTS9,RSPRY1,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.24E-07 1.57E-03 2.57E-06 2.33E-05 24 76 "SYT13,SEPT7,PNPLA8,ELMO1,NYAP1,OLFM1,NSG1,GABRB3,STMN2,MAP6,MARK1,BEX5,PCSK1,SNX10,RTN1,NBPF1,SNAP25,MYCBP2,PEG10,CLASP2,ASXL3,VGF,CELF4,REEP1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.24E-07 1.57E-03 2.57E-06 2.33E-05 27 92 "EMILIN3,ALCAM,APAF1,PHYHD1,BCHE,NRP2,CACNA2D1,VCAN,ETV1,DLC1,PDLIM5,PCDH17,GHR,RASSF8,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,ZHX3,PEG10,ERCC6L2,RGMB,TRPS1,UBE3A,WRN,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K4 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 3.33E-07 1.62E-03 2.64E-06 2.39E-05 109 657 "EMILIN3,SRPX,ARHGAP20,APOC2,CDC14B,CDK10,SPTBN4,ZFYVE28,ARRB2,ATP1A3,ADGRB2,BARD1,SEC11C,ZNF599,CACNA1G,GPC2,IL33,LDLRAD4,CFAP410,CA12,RUNX1T1,KCNAB3,CDO1,CRLF1,VAX2,PCYT1B,ABI3BP,CRYBB1,ANKRD44,CRYM,SNCAIP,CSF1R,DZIP3,FAM107B,DUSP9,EBF1,EDIL3,RASA4,ELN,LRRC17,CEP85L,ETV1,TMEM132C,PTK2B,FCGRT,HPCAL4,ZMYND15,SYT3,TRIM16,ST6GALNAC3,STAU2,ABLIM2,TVP23A,FYB1,TMEM8B,NTNG2,ZNF276,RASSF8,HLF,SYNPO,ICA1,IGF1,KNDC1,SCIN,KCNJ5,KIT,GPR155,SRSF12,TCEAL5,NFE2L2,NPY,PDE4D,PDPK1,PLCL1,EXOSC10,PRKAR1B,PTPRB,STRC,ACSS3,NWD1,ZCWPW1,ZMAT4,DUSP15,REV3L,ZFHX4,LRRK2,DGLUCY,MRAS,SH3GL3,ASAP3,PREX2,DHX30,SLC8A1,LIMCH1,ARHGAP26,SAMSN1,PLCB1,ALG1,ADGRL3,SATB2,SYNE1,PHF24,FAM189A1,AMACR,TRPS1,CADM2,DNAH10,FRMD6,DPF3" Coexpression Atlas GSM605843_500 "Plasmacytoid, DC.pDC.8-.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 3.36E-07 1.63E-03 2.66E-06 2.41E-05 76 412 "ABHD6,FMNL2,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ZBTB10,ATP1A3,DDR1,CD38,STOML1,LY86,MAGED1,ZNF521,CST3,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,TOM1,DUSP9,SNX29,EGFR,PLXNC1,CEP85L,TLR7,EYA1,CHST15,TMEM107,HVCN1,AK8,FYN,GPR162,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,MATN2,ADAM11,MEF2C,MX1,MYO5A,P2RY13,NUCB2,PLTP,ROGDI,ZDHHC14,PPM1E,ST8SIA1,BTBD3,CCDC88A,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,CYB561A3,SLC44A1,TNS1,P2RY12,LAT2,EVI5,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k5_500 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.38E-07 1.64E-03 2.67E-06 2.42E-05 37 150 "LCORL,PKP4,BACH1,RUNX1T1,ZNF445,SRSF11,RBM39,AIF1L,ZC3H11A,EDNRA,EIF4G1,EPB41L2,SRRM1,SMC2,LPAR4,MAP4,CHIC1,MEIS1,MEIS2,MID1,MSI1,PCSK5,TMEM255A,TMLHE,MEG3,ATXN2,TRA2B,SLC12A2,TET1,ZC3H13,PRRC2C,SYNE2,CBX5,R3HDM1,SSBP2,FLRT2,GAN" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_1000 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.68E-07 1.79E-03 2.90E-06 2.63E-05 129 813 "ABHD6,RNF157,ADORA1,PCDH19,DOC2A,AMPH,APBA2,EPB41L5,CDC14B,ARRB2,ZNF599,PROM1,BMP7,CA4,CA12,CALB1,CAMK2B,TBRG4,CRLF1,FAM189A2,PICK1,COL11A2,NSL1,CREM,CRYM,KIAA0040,GREB1,LYPD1,SNAP91,SV2B,USP3,DUSP9,HEYL,PCOLCE2,EIF1,EMX2,EPHB1,MRPL37,EYA1,CD320,RACK1,ST3GAL6,FKTN,SLC9B2,SPSB4,FGFR1,SCARA3,IP6K2,PSD2,JKAMP,HVCN1,TRIM16,RASL10A,CGREF1,TVP23A,GALC,IGSF5,TUBGCP4,BRD8,AIFM3,ADGRA3,DIDO1,PRDM5,CIT,CLASRP,FAM107A,HAS2,HP,DHX35,KCNJ5,KCNJ16,LIG4,PAXBP1,CLEC18A,MARK1,MAT2A,TM6SF1,MID1,PTOV1,TAGLN3,MYCN,VWA2,NPY,NPTX1,OXTR,CNTN3,CDK18,PRTG,PDE1C,OLA1,PLXNB1,ANKRD16,PSAT1,POLG,CEP41,PRODH,NDUFS7,LAMA1,PTPN13,PTPRD,NKAIN1,CCDC40,GAL3ST4,DUSP15,EMID1,PLPPR3,SALL1,MAPK12,SCN8A,ZNF821,SH3BGR,ANKRD6,SLC4A3,DHX30,BDP1,TMEM150C,CAMTA1,MCF2L,TAF9,HEY1,CA14,ZNF184,MAP3K12,TMEM178A,HPS4,URM1,PCBP4,PARP11,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.90E-07 1.90E-03 3.07E-06 2.78E-05 119 736 "NDRG2,ADCY5,PLEKHH1,TAOK1,SPARCL1,PI16,APC,DDO,BCAS1,ASPA,ATP2A2,MYOM1,ADAM23,NRP2,GPR146,DST,CACNA2D1,CAST,ENTPD2,LRRFIP1,PLEKHB1,AKAP6,ABI3BP,CLOCK,GDA,OSBPL3,CNTNAP2,MFAP3L,CHRDL1,DMD,DMPK,CPEB2,DTNA,HIPK3,TMTC1,OPTN,MBNL2,PCOLCE2,RCAN2,NCALD,MRVI1,NRN1,FGF1,FHL1,C2orf88,FUT9,CHL1,GALNT15,IGSF5,GCNT2,ADAM28,LYVE1,PRUNE2,TPPP,GSN,BVES,HLF,HNMT,IFI16,IL6ST,SLC35G1,KCNF1,MAP4,MBNL1,MBP,NFIX,NPTX2,PDE4D,ABCB1,CCSER2,PLCL1,JAKMIP1,FA2H,PRKAB2,PRKCB,DIRAS2,PTPRB,RASGRF2,ZDHHC14,TRIM68,RGS4,CLIP1,RYR3,SCN7A,STUM,SH3BGR,CPEB3,FHOD3,LIMS2,SLC14A1,CPEB4,SNAP25,FNBP1,DBNDD2,ATP10B,SYN2,TACC1,SLC44A1,ENHO,NACC2,TIMP4,TLR4,ERCC6L2,TNS1,TPM1,TPM2,RGMB,SYNPO2,PPIL6,UCHL1,RBFOX3,AGMO,ZBTB38,PLSCR4,RGS7BP,FAM13C,DOCK8,ADAMTSL3,MSRB3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.96E-07 1.92E-03 3.11E-06 2.82E-05 72 385 "RALGAPA1,EMILIN3,USP31,TAOK1,ALK,OGT,APAF1,APC,NRP2,BMP7,SCAPER,CACNA2D1,ZMYM4,CNRIP1,HAPLN1,VCAN,PUM1,TM9SF4,PDCD6IP,EDNRA,EDNRB,HIPK3,EIF4G1,DCTN4,VPS13B,EPHB1,ETV1,DLC1,SEC24B,SMC2,CAMKK2,GABRA3,IQGAP2,PCDH17,FERMT2,GRIA2,BACH2,KIF2A,LIFR,LIMS1,CHIC1,PPM1L,NEK1,PIK3C2A,MBOAT7,KANSL1,BCAS3,REV3L,SETD5,MEG3,CLIP1,TNFRSF19,NAPB,CPEB4,KIF13A,MYCBP2,CLASP2,RGL1,STX1A,DNMBP,ADGRL3,AGTPBP1,TBL1X,MGRN1,PUM2,ASXL3,ERCC6L2,RGMB,TRPS1,ZNF23,STOX2,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.22E-07 2.05E-03 3.31E-06 3.00E-05 44 195 "ESYT2,SRPX,CADPS,CACNA2D1,CNTN1,CNRIP1,AKAP12,VCAN,GRIN3A,CASP8AP2,EPB41L2,MRVI1,MEGF10,RAB40B,RASSF8,HAS2,HNMT,NEGR1,NKD1,LAMA2,LIMS1,MEIS1,MMP16,NTRK2,CLDN11,PDE3A,GPR85,TMOD2,ZIK1,PTX3,FAT4,ZFHX4,LRFN5,SH3GL3,BTBD3,PLCB1,CUX2,TCF12,FAM189A1,ZFPM2,TPM2,SYNPO2,FAM13C,MRPL47" Coexpression Atlas ratio_SC_vs_MESO_2500_K3 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 4.24E-07 2.06E-03 3.32E-06 3.01E-05 124 776 "SYN3,TMEM132B,UNC5A,SEMA6A,SYT13,DOC2A,LRFN1,VAT1L,PPP4R4,CARMIL3,CACNA1A,CLDN10,DCLK1,CHRNA4,FAM19A5,PCYT1B,FAM149A,ANKRD35,IGDCC3,NECTIN3,CRMP1,C1QL2,LRRC3B,GALNT9,RIMS4,FAM131B,HDAC9,KATNAL2,BRINP1,ARMCX4,JAKMIP2,PARD6A,CHRDL1,HS3ST2,DPYSL2,AASS,EPHB1,ETV1,PIPOX,PPP1R1B,ZNF589,OLFM1,MAD2L2,HPCAL4,FLT1,SYT3,CSPG5,NSG1,TVP23A,SRRM4,IGSF5,RUNDC3A,TTBK1,TOX3,GNG4,TDRKH,LPAR4,MCHR1,PCLO,LINGO1,ARHGAP36,C9orf129,LRRC75A,CELF5,SHISAL1,KNDC1,SCIN,KCND2,KCNN2,KCNN3,KHK,KIF5A,CAMK2N2,SCAMP5,FXYD7,NEFM,NELL2,NOVA2,NPTX2,NTRK3,EPB41L4B,FSD1,PPP2R2B,GDPD2,PTN,PTPRN,TMEM145,NKAIN1,ZMAT4,RORB,STX1B,PPM1E,NLGN1,SEPHS1,TRERF1,NMNAT2,SOX21-AS1,STAC2,NECAB1,RHBDL3,ARHGEF9,ARC,SYP,SYT1,COBL,MTCL1,PJA1,WSCD1,SLC19A3,RNF175,CHST8,ENHO,RELL2,ANKRD24,KCNE5,VGF,VSNL1,TSPAN11,RBFOX3,TCEAL7,KCNAB1,TMEM63C,NETO1,FAM198A" Coexpression Atlas GSM538242_500 "Myeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.25E-07 2.06E-03 3.32E-06 3.01E-05 74 400 "FMNL2,PTCHD1,ALCAM,SEMA7A,FGD2,CASK,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,SLC4A8,CSF1R,USP6NL,CYBB,DOCK4,HDAC9,MYADM,CDON,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,SIRPB1,GATM,GFRA2,RAB30,ADAP1,GSN,SLC2A6,FRMD5,LRRC25,IL6R,ITGAM,JAK2,KIT,ASPRV1,ADAM11,AFDN,ADAM22,MYO5A,PFKFB3,PLTP,RASGEF1B,PRKCB,PTK2,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SEMA6D,ST8SIA1,SLC8A1,ARHGEF40,CCDC88A,SAMSN1,RGL1,SULF2,TMEM150C,ADGRL3,KIAA0930,CYB561A3,SLC44A1,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.44E-07 2.16E-03 3.47E-06 3.14E-05 51 241 "CC2D2A,TMEM108,SLC4A4,MYRF,CALB1,KALRN,CNTFR,AKAP5,ZNF521,CLIP3,BOC,RHOBTB1,DNM1,TSPAN5,SEMA3D,C8orf37,ABCA8,FLNC,NSG1,TRAF3IP2,DENND2A,CSDC2,TCEAL6,NKD1,KCND2,LAMP2,MAP2,MATN2,MEIS1,NME4,PIK3R1,PCDH18,LAMA1,PTN,PTPN13,MEG3,KCNIP1,ZNF354C,CCDC112,SATB1,DZIP1,PKNOX2,PEG10,ZFPM2,ASXL3,ZNF346,TRPS1,FLRT2,PLEKHH2,ZFP37,KCNAB1" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.72E-07 2.29E-03 3.68E-06 3.33E-05 127 801 "RALGAPA1,ABCF1,METAP1D,ADORA1,DOC2A,OGT,PKP4,APC,EPB41L5,PHYHD1,CDC14B,PDE8B,PROM1,BMP7,BMPR1B,CA4,CA8,CALB1,RGN,LRBA,CRLF1,B4GALT6,SLIT2,CLCN3,FAM149A,COL9A3,AHCTF1,SLC35F1,RBM39,CRYM,IPCEF1,CNTNAP2,KIAA0040,UBXN2A,CTH,GREB1,ARHGAP24,MFAP3L,DDX46,DUSP9,HIPK3,SEMA3D,EIF5,TENM1,SRPK3,EIF1,EMX2,EPB41,MED12L,SPSB4,FGF12,SUCO,SYNCRIP,SMC2,PDLIM5,RASL10A,CAMKK2,MPP6,GALC,IQGAP2,IGSF5,PPARGC1A,MAP7D2,CNTRL,GRB10,DIDO1,FRMD5,ICA1,SCIN,KCNJ16,L1CAM,KITLG,MID1,NEK1,VWA2,CNOT4,OCRL,OLA1,PIK3C2A,PLXNB1,PSAT1,MBOAT7,KANSL1,MAPK4,LAMA1,EML5,RASGRF2,DPF2,RET,REV3L,EMID1,CLIP1,SALL1,SCN8A,HES6,HKDC1,FHOD3,FAM81A,DHX30,LIMCH1,STX1A,PRRC2C,TMEM150C,PJA1,DNMBP,TBL1X,MGRN1,WSCD1,NSD1,ERCC6L2,R3HDM1,RGMB,ELP5,TRIO,DCBLD1,SSBP2,RPRM,UBE3A,UGT8,VLDLR,VSNL1,ZNF23,ZNF24,EMX2OS,TMEM178A,FIP1L1,PCBP4" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k5_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.76E-07 2.31E-03 3.70E-06 3.35E-05 78 430 "USP31,ADGRF5,SHROOM2,ARRB1,NRP2,ARHGEF7,LDLRAD4,CA8,LDB2,CD86,SCARB1,CD38,LY86,CNRIP1,CSF1R,PPP1R16B,CYBB,KIF26A,RASSF2,ELMO1,FAM107B,EDNRB,EBI3,IGSF6,TLR7,SIRPB1,F8,DLC1,FCGR1A,FLT1,FYB1,PCDH17,GGTA1P,LYVE1,GPR12,NCKAP1L,ICA1,IRF8,IGF1,PIK3AP1,MAP4,TM6SF1,MEF2C,MSR1,MYO7A,NFE2L2,P2RX7,PDE4B,GNG2,RELN,PTPRB,TMEM255A,ATP8B4,SGK1,FAM102A,ST8SIA1,SLA,PREX2,SLC11A1,LIMCH1,ARHGAP26,SAMSN1,THSD1,NEK4,RGL1,SLC37A2,TAL1,KLHL4,ARHGAP9,SIK3,TEK,TLR4,VAV1,WIPF1,AMZ1,PLD4,RGS7BP,FAM13C" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.98E-07 2.42E-03 3.86E-06 3.50E-05 46 209 "USP31,OGT,APC,RNF182,BMP7,FOXN3,SUSD5,VCAN,DNM1,SEMA3D,ETV1,DLC1,FGFR1,SUCO,IQGAP2,GFRA2,GRIA2,CACFD1,RASSF8,BACH2,RBPJ,CHIC1,MEIS2,SAMD5,OCRL,CNTN3,OLA1,KANSL1,PTPRG,PTPRO,TMEM255A,RBBP6,REV3L,ROBO2,ZHX3,CLASP2,TROVE2,VPS13A,ADGRL3,CUX2,PCDHB7,ERCC6L2,RGMB,TRPS1,NAV3,MSRB3" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_500 dev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.98E-07 2.42E-03 3.86E-06 3.50E-05 76 416 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,ADAM15,NRP2,ARHGEF7,LDB2,CD38,MS4A7,ABCG2,LY86,HAPLN1,CSF1R,CYBB,DOCK4,RASSF2,PITPNC1,ELMO1,EBF1,EDNRB,PLEKHA1,CALCRL,RASGRP2,FAM198B,CORO2B,DLC1,FLT1,PDLIM5,FYB1,FYN,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,MAP4K5,ICA1,IGF1,KIT,LMO2,TM6SF1,MEF2C,KITLG,LAYN,PDE4B,ABCB1,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,RASA3,SGK1,FAM102A,PREX2,BTBD3,LIMCH1,THSD1,PLCB1,KLHL4,TCF4,DOCK9,TEK,HEY1,DCBLD1,WIPF1,ZNF711,ADAMTS9,NAV3,FAM13C" Coexpression Atlas PCBC_ECTO_blastocyst_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 5.41E-07 2.63E-03 4.19E-06 3.80E-05 86 490 "KCNH8,AXIN2,ADORA1,LGR5,RASL11B,KIF1A,BMP7,CA4,CAMK2A,CCK,NOG,IGLON5,CNTFR,COL9A1,COL9A3,COL11A2,GAL3ST1,NRG2,IGDCC3,HAPLN1,LRRC3B,CNTNAP2,PLCXD3,BOC,DGKG,LYPD1,SNAP91,CDON,DPP6,EMX2,ADGRV1,CLVS1,TMEM132C,SPSB4,ATP13A4,CHL1,LPAR4,UBE2QL1,IGFBPL1,SHISA6,CELF5,INSM1,CLEC18A,MAP6,TCEAL5,NELL2,NNAT,NPY,NTRK3,IGSF11,CNTN3,PAX6,PRTG,ENPP2,SDK2,NECAB2,NKAIN4,RELN,LAMA1,PTPRD,ZFHX4,HUNK,KCNIP1,LRFN5,TMEM200C,ARX,SOX3,SOX15,NMNAT2,CLSTN2,SST,RIMBP2,CA14,CLEC2L,VGF,ZIC1,ZIC2,KCNT2,EMX2OS,CRB2,DPYSL5,LAMP5,CADM2,GAL3ST3,DOCK8,JPH3" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k1_1000 kidney_P3_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.52E-07 2.68E-03 4.27E-06 3.87E-05 50 236 "ABR,RNF157,MTUS1,TXNDC16,ALCAM,AMPH,ADAM23,BCL7A,BMP7,CACNB4,CDH2,FAM19A5,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,SPOCK2,SNAP91,EDNRA,HEYL,ETV1,EYA1,FGFR1,MAD2L2,SCARA3,STAU2,TDRKH,GRIK4,FAM107A,HAS2,NEGR1,LSAMP,MEIS2,ADAM22,NME4,CNTN3,SMOX,ZCWPW1,ROBO2,HUNK,SALL1,GKAP1,SP4,ELOVL4,CAMTA1,TRIM2,PCDHB9,LAMP5" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 5.76E-07 2.80E-03 4.45E-06 4.03E-05 28 100 "HAP1,SRSF11,LHX2,IGDCC3,RIMS2,SCRN1,JAKMIP2,ADGRV1,CLVS1,DLL3,SRRM4,TOX3,MAP7D2,STMN2,RNF165,SOX21,TOX2,IGFBPL1,ZIC5,SHC3,MYT1,NRCAM,HSPA4L,ARX,NR2E1,ZIC1,ZIC2,DPYSL5" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k5_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.81E-07 2.82E-03 4.47E-06 4.06E-05 41 178 "EMILIN3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,SFMBT2,BARD1,BCHE,CACNA2D1,SRSF11,SOCS6,SLIT2,CRHBP,VCAN,MYEF2,ETV1,DLC1,PDLIM5,ARFIP1,PCDH17,GHR,RASSF8,ZDHHC15,RBPJ,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,MYO6,ST8SIA1,ZHX3,PEG10,AGTPBP1,ERCC6L2,RGMB,TRPS1,UBE3A,WRN,NETO1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.84E-07 2.84E-03 4.49E-06 4.07E-05 36 147 "SPARCL1,ALCAM,ARHGAP20,SLC4A4,MYRF,SLIT2,CNTFR,AKAP5,ZNF521,VCAN,BOC,DNM1,TSPAN5,EDNRA,LRRC17,FLNC,DENND2A,GFRA2,FREM1,GUCY1A1,TCEAL6,NKD1,MATN2,MEIS1,NEFM,NME4,PCDH18,LAMA1,PTN,TMEM255A,MEG3,PEG10,ASXL3,TRPS1,FLRT2,VSNL1" Coexpression Atlas PCBC_EB_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500 PCBC 6.23E-07 3.02E-03 4.78E-06 4.33E-05 87 499 "AGT,SORCS2,SPARCL1,CACNA1G,MYRF,CABP7,CAMK2A,CBLN1,NOG,LHX2,IGLON5,CNR1,COL9A1,AKAP5,IGDCC3,RIMS4,PHACTR3,CNTNAP2,SNAP91,DUSP9,EDN3,ADGRV1,NRN1,TMEM132C,FOXF2,CSPG5,SRRM4,CPLX2,GFRA2,FREM1,CCDC184,STMN2,GRIA2,C1QL4,GRM8,GUCY1A1,UBE2QL1,IGFBPL1,CELF5,C2orf72,IGF1,NKD1,INSM1,CDH20,CLEC18A,MAP6,MAPT,TAGLN3,MYT1,NEFM,NELL2,NNAT,NTRK2,NTRK3,PCDH8,PDZRN4,NECAB2,MAGEL2,PPP2R2B,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,ZFHX4,HUNK,KCNIP1,RTN1,TMEM200C,SNAP25,CABCOCO1,SOX3,CLSTN2,SST,SSTR2,SYT5,ASXL3,RIMBP2,ZIC1,KCNT2,CRB2,DPYSL5,FAM181A,PRRT4" Coexpression Atlas PCBC_ECTO_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 6.23E-07 3.02E-03 4.78E-06 4.33E-05 87 499 "VAT1L,KIF1A,CA4,CAMK2A,CCK,LHX2,IGLON5,COL9A1,GAL3ST1,NRG2,IGDCC3,HAPLN1,CNTNAP2,PLCXD3,DGKG,LYPD1,SNAP91,CDON,EMX2,ADGRV1,CLVS1,ATP13A4,IP6K3,SYT17,GPR162,TOX3,AIFM3,PRUNE2,LPAR4,SOX21,GUCY1B1,UBE2QL1,NXPH3,IGFBPL1,CELF5,INSM1,CLEC18A,MAP6,TAGLN3,MYO7A,TCEAL5,NELL2,NPY,IGSF11,PAX6,PRTG,ENPP2,SDK2,NECAB2,MAGEL2,NKAIN4,LAMA1,ELOVL2,PTPRD,STRC,TMEM255A,ZFHX4,KLHDC8A,HUNK,TMEM200C,ARX,PKNOX2,DMRTC1,SOX3,SOX15,LMO3,CLSTN2,SOX21-AS1,PCDHA6,PCDHA3,PCDHA2,NR2E1,RIMBP2,CA14,CLEC2L,RBFOX3,ZIC1,KCNT2,EMX2OS,CRB2,MKRN3,DPYSL5,LAMP5,CADM2,GAL3ST3,DOCK8,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.35E-07 3.08E-03 4.86E-06 4.40E-05 39 166 "USP31,PCDH10,DPP10,APC,ADAM23,NRP2,CACNA1B,CNR1,COL9A1,CRHBP,VCAN,PLCXD3,BRINP1,MFAP3L,GRIN3A,TUBB3,FOXF2,MEGF10,IQGAP2,SYT17,GFRA2,PCDH17,BACH2,IFI16,MAP4,NDP,NTRK2,CLDN11,MAPK10,PRPH,PTPRO,REV3L,RGS4,ZFHX4,RTN1,ANKRD6,SNAP25,CUX2,RGMB" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_200 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.35E-07 3.08E-03 4.86E-06 4.40E-05 39 166 "ADD1,ARHGAP20,LCORL,PKP4,BACH1,IL33,RUNX1T1,SLIT2,COL4A5,RBM39,ZC3H11A,EDNRA,EIF4G1,EPB41L2,LRRC17,LPAR4,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,NFIX,PCDH9,NALCN,PIK3R1,C1orf54,TMLHE,MEG3,TRA2B,ARX,PRRC2C,KLHL4,CBX5,R3HDM1,NR2C2,SSBP2,FLRT2,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.59E-07 3.20E-03 5.03E-06 4.56E-05 38 160 "SORCS2,C1QTNF3,SYT13,CADPS,IL33,RUNX1T1,LDB2,CDH2,FAM171B,BOC,EBF1,SEMA3D,TMTC1,CALCRL,GFRA2,RAB40B,UBE2QL1,IGF1,KCND2,MATN2,MEIS2,CLDN11,PCDH8,PIK3R1,PTPRD,FAT4,RNASEL,LGI2,MEG3,SATB1,CSRNP3,MTERF2,MAPKBP1,TROVE2,ZFPM2,ITGB3BP,SSBP2,LYPD6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.76E-07 3.28E-03 5.15E-06 4.67E-05 82 463 "ASPHD1,RNF157,VAT1L,ARHGDIG,CADPS,KIF1A,NRP2,CACNA1G,DCLK1,CHGB,RAB33A,CLTB,PICK1,CNTFR,FAM171B,CRMP1,CLIP3,VCAN,PLXNA4,SCRN1,BRINP1,GRIN3A,DNM1,EDNRA,LRRC17,EYA1,TUBB3,FGF13,FLNC,NSG1,TPPP3,TVP23A,SYT17,IGSF5,GFRA2,FREM1,GLI2,KCNMB4,GNAO1,STMN2,GSTM5,ACOT7,L1CAM,SYTL4,MATN2,TAGLN3,NEFM,NELL2,NFIX,NNAT,NME4,NPY,PCBP3,NTRK2,NTRK3,CLDN11,SLC10A4,FXYD1,PMP22,POLR2F,NKAIN4,MAPK10,PRPH,MASP1,EML5,TMEM255A,TSPY26P,RET,HUNK,RTN1,SNAP25,SST,SULF2,SEPT3,ADAMTS17,SYP,SYT1,ASTN2,CUX2,UCHL1,MTCH1,VLDLR" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.96E-07 3.38E-03 5.30E-06 4.80E-05 36 148 "ANK2,VAT1L,CADPS,NRP2,DCLK1,RAB33A,VCAN,PLXNA4,SCRN1,EDNRA,LRRC17,EYA1,TUBB3,NSG1,TPPP3,IGSF5,GFRA2,GNAO1,STMN2,L1CAM,SYTL4,MATN2,TAGLN3,NEFM,NNAT,NTRK3,SLC10A4,TMOD2,PMP22,MAPK10,PRPH,EML5,RTN1,SNAP25,SST,UCHL1" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_1000 kidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.05E-07 3.42E-03 5.36E-06 4.86E-05 136 878 "MTUS1,HECW2,OSBPL8,C1QTNF1,ADGRF5,PI16,APBB2,EPB41L5,APLP1,UPRT,ARRB1,PDE8B,ASPA,TMEM108,ATP1B3,CFLAR,CACNA2D1,CALB1,THSD7A,CD38,CLTB,ARHGEF6,CLOCK,ANKRD44,SNCAIP,CSF1,LRRC3B,CST3,KIAA0040,CYBB,DOCK4,ARHGAP32,ARHGAP24,DGKB,AIF1L,PITPNC1,NR1D2,ECM2,EBF1,TSPAN5,EDNRB,HIPK3,TMTC1,FRY,OPTN,IRAK4,CALCRL,RCAN2,RASGRP2,CEP85L,TLR7,F8,ACSL4,CORO2B,DLC1,ST3GAL6,FGF1,FLT1,UFM1,PDLIM5,ST6GALNAC3,GALC,IQGAP2,ERAP1,INPP5K,MALT1,FERMT2,STMN2,PARD3B,GUCY1A1,GUCY1B1,RASSF8,ZHX1,FRMD3,GABARAPL2,SYNPO,IFI16,IL6ST,INPP5B,KCNJ16,LIFR,LMO2,MAPT,MSR1,LAYN,MYO6,NCF2,P2RX7,P2RY1,PDE3A,PDE4B,SERPINI1,PIK3R1,CCSER2,PLCL1,SEPT4,FA2H,MINDY2,PKIA,SNRK,PTH1R,PTN,PTPRB,PTPRO,RIPOR1,ZDHHC14,ZMAT4,ROBO2,LRRK2,ST6GALNAC6,SCN7A,SGK1,SLA,FAM81A,PREX2,SLC12A2,CPEB4,LMBRD1,DDN,ITPRID2,NXT2,RGL1,KANK1,PLCB1,TMEM150C,ANKRD12,SYNE1,TNS2,FRYL,TEK,TLR4,TNS1,SGK3,PLEKHH2,PLSCR4,DOCK8" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k2 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.07E-07 3.43E-03 5.37E-06 4.86E-05 35 142 "KLHL13,SPARCL1,IGDCC4,CADPS,ADGRB2,FOXN3,AKAP12,PLCXD3,CALCRL,GFRA2,LYVE1,LPAR4,NEGR1,IGF1,NKD1,RBPJ,KCND2,MATN2,MMP16,NRBP2,NFIX,CLDN11,PTCH1,TMEM255A,LGI2,ZNF354C,SATB1,TROVE2,SYT1,PUM2,HIF3A,ZFPM2,TPM1,SSBP2,TUBB2A" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.11E-07 3.45E-03 5.39E-06 4.88E-05 33 130 "ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,RUNX1T1,CBLN1,VCAN,RIPOR2,ARMCX2,EDNRA,HEYL,EGFR,LRRC17,EYA1,DLC1,SEPT9,GFRA2,FREM1,GHR,GLI2,GUCY1A1,PCDH9,PLTP,SH3KBP1,LRRN3,LAMA1,PTCH1,ROBO2,ARMH4,SULF2,STOX2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 7.18E-07 3.49E-03 5.43E-06 4.92E-05 24 79 "ATP2B2,SRSF11,SCRN1,ADGRV1,CLVS1,SPSB4,DLL3,SRRM4,RNF165,TOX2,FRMD5,IGFBPL1,ZIC5,MAP2,SHC3,NRCAM,MAPK10,WSCD1,FRYL,MGAT5B,ZIC1,DPYSL5,STOX2,FZD3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k4 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.46E-07 3.62E-03 5.63E-06 5.10E-05 26 90 "USP31,VAT1L,CACNA1B,CHGB,CNR1,CNTN1,TMEM130,SPOCK3,TUBB3,FOXF2,GNG4,STMN2,IFI16,KIF5A,MAP4,MYH3,NEFM,MAPK10,PRPH,RGS4,ZFHX4,RTN1,SNAP25,CLASP2,PCDHB7,FSTL5" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_200 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.47E-07 3.63E-03 5.64E-06 5.11E-05 39 167 "ARHGAP20,LCORL,BACH1,RUNX1T1,SLIT2,PLAA,COL4A5,RBM39,PUM1,ZC3H11A,EDNRA,EIF4G1,EPB41L2,MEX3B,SMC2,LPAR4,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,PCDH9,PIK3R1,C1orf54,TMLHE,ROBO2,MEG3,TRA2B,ARX,ZC3H13,RBM26,KLHL4,CBX5,R3HDM1,SSBP2,FLRT2,ADAMTS9,GAN" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K3 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 7.62E-07 3.70E-03 5.73E-06 5.20E-05 78 435 "SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ZFYVE28,ARRB2,PDE8B,ATP1A3,BARD1,NRP2,KSR1,IL33,LDLRAD4,CFAP410,CAMK2A,CAMK2B,KCNAB3,BAG4,CREM,HAPLN1,CRYBB1,TIAM2,SNX29,TMTC1,RASA4,RASGRP2,NCALD,CDKL3,PTK2B,ZMYND15,DLL3,ABLIM2,FYB1,TMEM8B,LYVE1,NTNG2,GNG4,ADAP1,GSN,GUCY1B1,SCIN,KLHL23,GPR155,MITF,MYH3,MYO6,NPR2,ETFRF1,PDE4B,PDE4D,ENPP2,PDPK1,PILRA,PRKAR1B,MASP1,GDPD2,STRC,PID1,ZCWPW1,ZNF493,ZMAT4,DUSP15,KCNIP3,ASAP3,CCDC92,INAVA,SAMSN1,FLRT2,MICU3,EML6,LAMP5,CADM2,DNAH10,PRRT4" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_500 kidney_P3_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.63E-07 3.70E-03 5.73E-06 5.20E-05 69 370 "NDRG2,KLHL32,RNF157,MTUS1,PCDH19,ALCAM,AMPH,VAT1L,ADAM23,BARD1,BCL7A,CACNA1G,CA4,CA12,CACNA2D1,CACNB4,CDH2,SLIT2,CLIP3,CRYM,SNCAIP,VCAN,CTH,CENPL,SPOCK2,GSDME,SNAP91,SV2B,RAB39B,EDNRA,HSD17B14,EYA1,ST3GAL6,FGFR1,SCARA3,MTHFD2,IGSF5,KDM2B,TDRKH,FAM107A,HAS2,NEGR1,CLEC18A,MAT2A,TM6SF1,MSI1,ADAM22,MYO6,NME4,NPY,CNTN3,PTN,PTPN13,ROBO1,GLDN,SALL1,CNKSR2,SOX11,TMEM150C,TACR1,CUX2,TRIM2,PCDHB9,AKTIP,HEY1,LAMP5,SLC38A1,ADAMTS9,FZD3" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_500 DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.67E-07 3.73E-03 5.76E-06 5.22E-05 74 406 "PLEKHH1,ADORA1,PCDH19,DOC2A,EPB41L5,LGR5,CDC14B,BMP7,CA4,CLDN10,CD38,KIAA0040,CTH,GREB1,ARHGAP24,SCRN1,DUSP9,HIPK3,HEYL,EIF1,EMX2,RASGRP2,EPHB1,ST3GAL6,SPSB4,FGFR1,FLT1,CGREF1,GALC,SYT17,IGSF5,GCNT2,PCDH17,AIFM3,ADGRA3,GPER1,GRB10,FAM107A,HP,KCNJ16,TTYH2,CLEC18A,TM6SF1,KITLG,VWA2,NRCAM,OXTR,ENPP2,PIK3C2A,RETREG1,PLXNB1,SCHIP1,MBOAT7,KANSL1,MAPK4,LAMA1,ELOVL2,PTPRO,RIPOR1,NKAIN1,EMID1,SALL1,SCN8A,FHOD3,FAM81A,DDN,APOM,STX1A,TMEM150C,WSCD1,HEY1,ERCC6L2,TMEM178A,SPATA13" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500_k3 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.17E-07 3.97E-03 6.12E-06 5.55E-05 43 193 "AXIN2,SEMA6A,FGD2,PDE8B,ZNF599,BMP7,BMPR1B,CACNA1B,CALB1,CRLF1,B4GALT6,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,EMX2,SPSB4,FGF12,SEMA4D,RASL10A,MAP7D2,PADI2,FRMD5,L1CAM,KITLG,VWA2,NRCAM,PFKFB3,SEMA5B,SLC25A23,EML5,RASGRF2,RET,NUDT11,SCN2B,SHMT2,FHOD3,NUDT10,WSCD1,DCBLD1,RPRM,VSNL1,FSTL5" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.36E-07 4.06E-03 6.26E-06 5.67E-05 25 85 "EMILIN3,ADRB2,MYOM1,CACNA2D1,CNTN1,COL9A1,VCAN,PLCXD3,NCALD,PDLIM5,MEGF10,GFRA2,LIMS1,NPTX2,CLDN11,PCDH9,NALCN,PTX3,REV3L,SH3BGR,ERCC6L2,RGMB,SYNPO2,SSBP2,MSRB3" Coexpression Atlas ovary ovary Human Protein Atlas 8.51E-07 4.13E-03 6.36E-06 5.76E-05 32 125 "RASL11B,CBS,USP6,SNCAIP,PLCXD3,GREB1,PABPC5,LRRC17,ENPP6,CSDC2,GLI2,GNG4,LPAR4,GSTM5,SYTL4,NDP,EML5,TMEM255A,KLHDC8A,SCN7A,ARX,SLC4A3,CLSTN2,VWCE,ZFPM2,ASXL3,FLRT2,VLDLR,KCNT2,LAMP5,NAV3,DPF3" Coexpression Atlas GSM854299_500 "Plasmacytoid, DC.pDC.8+.SLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-3" "Immgen.org, GSE15907" 9.08E-07 4.41E-03 6.77E-06 6.14E-05 75 415 "ABHD6,FMNL2,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ATP1A3,SEC11C,ZNF599,DDR1,CD38,STOML1,LY86,MAGED1,ZNF521,CST3,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,PRKAG2,HVCN1,AK8,FYN,GPR162,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,MATN2,ADAM11,MEF2C,MYO5A,P2RY13,NUCB2,PGAM2,PLTP,TMEM231,ROGDI,ZDHHC14,PPM1E,ST8SIA1,CCDC88A,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,CYB561A3,SLC44A1,TNS1,C9orf85,P2RY12,LAT2,EVI5,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.43E-07 4.58E-03 7.02E-06 6.36E-05 26 91 "PCDH10,VAT1L,RUNX1T1,DCLK1,CDO1,ERC2,SPOCK3,EGFR,EYA1,TMEM132C,FOXF2,MEGF10,LPAR4,GRIA2,IFI16,MYH3,PCDH8,TRHDE,ZFHX4,ROBO1,CSRNP3,ANKRD6,SOX11,TROVE2,ADGRL3,PCDH20" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_200 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.78E-07 4.75E-03 7.27E-06 6.59E-05 40 175 "GALNT13,RNF150,C1QTNF3,ALCAM,DPP10,DOCK11,IL33,CACNA2D1,LDB2,RASSF2,EBF1,EDN3,SEMA3D,TMTC1,CHL1,IQGAP2,GGT5,RAB40B,GUCY1B1,RASSF8,NEGR1,IFI16,KCND2,LSAMP,NOVA1,PCDH8,RELN,FAT4,SALL1,CSRNP3,SCN7A,DZIP1,ST8SIA1,NEK4,PCDHB9,ASXL3,TLR4,ERCC6L2,PCDH20,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.83E-07 4.77E-03 7.29E-06 6.61E-05 36 150 "NCKAP5,PCDH10,USP37,INSYN2B,ZNF599,LDLRAD4,CH25H,CNR1,PCYT1B,SLC35F1,NCOR1,RIMS2,PITPNC1,DLX1,SEMA3D,UBE2E3,FOXF2,PPARGC1A,TOX3,KIAA1958,MAP4K5,VWA2,PCDH8,GPR85,OLA1,PLXNB1,FIGN,C12orf49,ROBO1,RPS20,CCDC112,ANKRD6,KLHL7,RPRM,WNT7A,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k2 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.91E-07 4.81E-03 7.34E-06 6.66E-05 64 337 "ACTN1,ADCY5,C1QTNF3,NT5C3B,ATP2A2,MYOM1,BCHE,NRP2,CA4,CACNA2D1,CFL2,AKAP5,SV2B,CPEB2,DTNA,ABCC5,CERCAM,SRPK3,NCALD,SPEG,MRVI1,FCGRT,FGF12,PRKAG2,GABBR1,BVES,HNMT,SHISAL1,IL6ST,ITGA7,ITPKB,KCNB1,KCNF1,KCNH2,KLHL23,MMP17,NPTX2,PDE4B,PDE4D,TMEM38A,SCHIP1,PRKAB2,PRKCB,PTGR2,RYR3,STUM,SH3BGR,SH3GL3,FHOD3,ABLIM3,FNBP1,ARHGEF9,SYN2,ENHO,NACC2,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,FAM13C,ACTR3B,ADAMTSL3,MSRB3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.03E-06 5.01E-03 7.63E-06 6.92E-05 33 132 "RNF157,FAM135A,LDLRAD4,RUNX1T1,CDH2,SLIT2,NCOR1,APPL1,ETV1,TMEM132C,UBE2E3,FOXF2,MEGF10,RAB40B,MAP4K5,IFI16,PCDH8,GPR85,PCDH18,GRAMD1C,FAT4,RGS4,ZFHX4,ARMH4,DZIP1,WDR37,ELOVL4,PLCB1,MTCL1,ADGRL3,TRPS1,MKRN3,SOCS4" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 1.03E-06 5.02E-03 7.63E-06 6.92E-05 85 490 "SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ZFYVE28,ATP1A3,ATP2B2,KIF1A,TTLL9,BARD1,NRP2,ZNF599,IL33,CA12,CACNA1B,CAMK2A,CAMK2B,KCNAB3,SRSF11,IGDCC3,CREM,CRYBB1,CRYM,PHF14,SCRN1,SNX29,RASGRP2,NCALD,CDKL3,ADGRV1,CLVS1,PTK2B,CORO2B,HPCAL4,ZMYND15,SEMA4D,DLL3,FUT9,ABLIM2,FYB1,GAD1,SRRM4,PPARGC1A,LYVE1,NTNG2,ADAP1,PCLO,SMAP1,KNDC1,SCIN,INSM1,HECTD2,GPR155,MID1,MITF,MYH3,MYT1,ETFRF1,PDE4D,ENPP2,PRKAR1B,MAPK10,DIRAS2,MASP1,GDPD2,STRC,ZMAT4,DUSP15,REV3L,KCNIP3,CCDC92,CCDC88A,INAVA,SAMSN1,ASXL3,STXBP4,RBFOX3,LAMP5,CADM2,DNAH10,PRRT4" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.03E-06 5.02E-03 7.63E-06 6.92E-05 27 97 "PKP4,BACH1,SRSF11,COL4A5,RBM39,ZC3H11A,EDNRA,EIF4G1,CALCRL,EMX2,EPB41L2,MEX3B,LPAR4,CHIC1,MMP16,CNOT4,PDPK1,RNASEL,TMLHE,SLC12A2,ZC3H13,CBX5,R3HDM1,SSBP2,ZNF711,ADAMTS9,GAN" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.07E-06 5.17E-03 7.83E-06 7.10E-05 25 86 "PCDH10,FAM135A,VAT1L,RNF182,LDLRAD4,DCLK1,SLC35F1,ERC2,HDAC9,TENM1,EYA1,TMEM132C,FOXF2,IFI16,MYH3,GPR85,FAT4,ZFHX4,CSRNP3,ANKRD6,ELOVL4,ADGRL3,PCDHB3,RPRM,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.07E-06 5.17E-03 7.83E-06 7.10E-05 25 86 "OSBPL6,PCDH10,CADPS,CACNA2D1,NRXN3,LY86,CNTN1,CNRIP1,VCAN,EPB41L2,NCALD,MRVI1,GUCY1A1,NEGR1,MMP16,CLDN11,NKAIN4,PTX3,LRFN5,SCN7A,CXXC4,PDLIM2,SYNPO2,PROCA1,NAV3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500 FaceBase_RNAseq 1.07E-06 5.21E-03 7.88E-06 7.15E-05 84 483 "EMILIN3,NCKAP5,NDRG2,ARHGAP20,LTBP4,GPRASP2,CDK10,TTLL9,ADGRB2,BARD1,CACNA1G,LDLRAD4,CACNA2D1,CAMK2A,SLC25A14,LONRF2,KCNAB3,CDO1,CRLF1,SRSF11,NRXN3,PPT2,CNTFR,ANKRD44,CSF1R,ARHGAP24,SPOCK2,DMD,SHANK1,SEMA3D,EGFR,ELN,TMEM35A,LRRC17,CHST15,FCGRT,FGF11,TRIM16,FYB1,TMEM8B,PCDH17,PPARGC1A,ZNF276,GSN,SYNPO,METTL21A,KLHL23,SRSF12,NEXMIF,TCEAL5,NCAM2,NELL2,NFIX,OGG1,CNTN3,PCDH9,PLCL1,PMP22,SDK2,MAGEL2,POU6F1,PRODH,MASP1,DEF8,ZMAT4,BAALC,EMID1,DGLUCY,FERMT1,NLGN1,CLSTN2,ADGRL3,SATB2,PHF24,FAM189A1,TMEM121,SYNPO2,KCNE5,TSPAN11,EML6,CADM2,NAV3,DPF3,SENP7" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.08E-06 5.23E-03 7.89E-06 7.16E-05 41 182 "NDRG2,ALCAM,ARHGAP20,LTBP4,ADAM23,CACNA1G,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SLIT2,CNTFR,VCAN,RIPOR2,ARHGAP24,ARMCX2,EDNRA,HEYL,DLC1,FLNC,GFRA2,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,LAMA2,PCDH9,FXYD1,PLTP,LRRN3,LAMA1,PTCH1,PTN,ROBO2,ARMH4,PKNOX2,SULF2,STOX2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.09E-06 5.27E-03 7.96E-06 7.21E-05 22 70 "TMCC3,KLHL13,PCDH10,NRXN3,KIAA0408,RCAN2,NSG1,FUT9,STMN2,SHISAL1,LSAMP,PDZRN4,POU6F1,MEG3,RTN1,SNCA,PEG10,LMO3,DOK6,UCHL1,CELF4,REEP1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.09E-06 5.30E-03 7.98E-06 7.23E-05 65 345 "APLP1,CDH2,CDO1,CDR1,COL4A5,ZNF521,CNRIP1,CRMP1,CNTNAP2,KIAA0408,BOC,DPYSL2,SEZ6L2,EDNRB,ENO2,ABCA8,TMEM132C,TUBB3,TMEM107,ERGIC3,LOXL3,STMN2,GRM8,ATOH8,IGFBPL1,LAMP2,LIFR,LRP1B,MID1,TAGLN3,NNAT,NTRK2,NUCB2,CNTN3,PAX6,PCDH9,PDE4D,PKM,PLTP,SDK2,NECAB2,NKAIN4,MAPK10,MASP1,PTN,TMEM255A,FAT4,ZMAT4,RFX3,HES6,GALNT10,SOX11,KDM3A,MYCBP2,CDK19,SYNE2,AGTPBP1,ZEB1,TCF12,ZIC1,ZIC2,ZNF711,TCEAL7,DNALI1,NHSL1" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Early fibroblastic progenitor Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Early fibroblastic progenitor Lungmap CCHMC 1.10E-06 5.35E-03 8.05E-06 7.30E-05 78 439 "NCKAP5,MTUS1,KLHL13,LTBP4,PARG,APOC1,CARS,CBR1,CDO1,SLIT2,RAB28,ABI3BP,NSL1,AKAP12,DOCK4,HDAC4,FBXL5,DDX46,DNM1,RCAN1,COPS4,PCOLCE2,LRRC17,RASGRP2,CLVS1,TUBA1B,CHST15,FHL1,CINP,GFRA2,TCERG1,GLI2,CIT,PSIP1,ZNF546,MAP2,MAT2A,MEIS1,MEST,KITLG,MID1,PTOV1,MYO6,NDP,NEK1,NRCAM,PFKFB2,GPSM2,FXYD1,PMP22,SCHIP1,SEPT4,LRRN3,NKAIN4,PRPSAP2,ZCWPW1,RBBP8,ERI2,CARF,RORB,RMI1,SCP2,SEC31A,ABLIM3,PREX2,SLC12A2,LIMCH1,PDLIM2,TCF4,TCF12,PUM2,TMPO,TNS1,TRO,FTSJ1,MAP3K12,HNRNPA3,IFT88" Coexpression Atlas ratio_SC_vs_DE_500_K3 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 1.12E-06 5.43E-03 8.16E-06 7.39E-05 14 32 "CALB2,CCK,SNCAIP,GALNT9,TMEM130,NPTX1,PCSK1,NKAIN4,PTPRO,KCNIP1,LMO3,CRB2,LAMP5,KCNAB1" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.13E-06 5.47E-03 8.20E-06 7.43E-05 120 759 "RALGAPA1,ACADM,PLEKHH1,OSBPL6,OGT,C6orf89,EPB41L5,CDC14B,ASPA,SLC4A4,CFLAR,CA4,CA12,CACNA2D1,ISPD,CLDN10,USP2,SLC16A4,CLCN3,CLTC,FAM189A2,SLC35F1,OSBPL3,IPCEF1,CTH,ARHGAP24,GUCD1,SNAP91,GOLT1B,EIF4G2,PAN3,EMX2,PIPOX,ZMYND10,SPSB4,FGFR3,SYNCRIP,SEMA4D,ATP13A4,FOLR2,CGREF1,FUT9,GALC,RAPGEF6,IGSF5,ALDH1L1,GHR,PPARGC1A,BRD8,AIFM3,GPD1,GRB10,DHX35,KCNJ16,PAXBP1,NCOA7,GPR155,CLEC18A,MAP4,AQP11,MITF,MYO6,MYO7A,MYO9A,SLC11A2,SETD4,IGSF11,PDE1C,ENPP2,PIK3C2A,RETREG1,PRIMPOL,ANKRD16,DRAM2,POU6F1,KANSL1,RANBP3L,MAPK4,BCAS3,LAMA1,PTH1R,ELOVL2,PTPN13,EML5,SH3TC2,REV3L,LRRK2,RYR3,SALL1,SCN8A,SUPT20H,KIF21A,FHOD3,FAM126B,SPATA7,ZHX3,MYCBP2,SPP1,RBM26,PBLD,APOM,NEK4,ADHFE1,PRRC2C,VPS13A,FAM208A,SATB2,VWCE,ERCC6L2,LRRC8A,RGMB,TRIO,AMACR,TRPS1,PPIL6,UGT8,VLDLR,ADAMTS9,SEMA3B,KLHDC1" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_500 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.18E-06 5.71E-03 8.55E-06 7.75E-05 44 202 "ABR,RNF157,AMPH,VAT1L,BARD1,BCL7A,BMP7,CACNB4,CDH2,CNTFR,CRYM,SNCAIP,VCAN,GSDME,SNAP91,DTNA,ETV1,EYA1,FGFR1,SCARA3,TMEM107,STAU2,MTHFD2,IGSF5,FREM1,TDRKH,FAM107A,HAS2,NEGR1,NME4,NPY,CNTN3,TSPY26P,SALL1,SLC4A3,NUDT10,CUX2,TRIM2,PCDHB9,HEY1,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k4_1000 dev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.18E-06 5.75E-03 8.59E-06 7.79E-05 88 514 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,SHROOM2,DOCK11,ADAM15,NRP2,ARHGEF7,LDB2,CD38,ARHGEF2,MS4A7,ABCG2,TMEM184B,ARHGEF6,CRMP1,HAPLN1,CSF1R,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,FAM107B,ECM2,EBF1,EDIL3,CALCRL,RASGRP2,STX2,DENND4A,CORO2B,FCGR1A,FLT1,UFM1,PDLIM5,TRIM16,FYB1,PCDH17,GGTA1P,LYVE1,HPGDS,GLUL,LILRB4,LPAR4,MAP4K5,NCKAP1L,ELOVL5,ICA1,IFI16,ITPKB,LIFR,LMO2,TM6SF1,MEF2C,MSR1,MYO6,PDE4B,PDE4D,SCHIP1,DRAM2,MAPK3,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,SGK1,PREX2,BTBD3,CPEB4,LIMCH1,SAMSN1,THSD1,KLHL4,TCF4,TEK,C18orf54,HEY1,TLR4,WIPF1,ZNF711,NAV3,FAM13C,ZDHHC20,RNF146" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_200 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.21E-06 5.85E-03 8.73E-06 7.91E-05 39 170 "ADORA1,AMH,SEMA7A,GAS7,LGR5,ARHGDIG,CADPS,SCRN1,JAKMIP2,ELMO1,PLPPR4,DTNA,MRO,PLXNC1,CERCAM,ERBB4,PTK2B,TUBB3,FGF13,AFF2,GATM,GPR37,SHISA6,KLHL23,SYTL4,MOV10,MYO7A,PGAM2,RASGEF1B,DUSP15,MRAS,KIF21A,SPP1,TACC1,THRA,BEX4,SGK3,ADAMTS9,WNK3" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.21E-06 5.86E-03 8.74E-06 7.92E-05 30 115 "SEMA7A,APOC1,CDC14B,TMEFF1,RGS11,DST,ST3GAL5,RGN,CDH2,GPRASP1,MRO,PLXNC1,CERCAM,FAM198B,AFF2,CAMKK2,GATM,GPR37,RABL2A,SYTL4,MOV10,ETFRF1,SEMA5B,RPS6KA2,MRAS,TSPYL2,SZT2,TST,ADAMTS9,WNK3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.25E-06 6.06E-03 9.02E-06 8.17E-05 60 311 "ABCF1,ADAM23,BLM,ZNF599,CACNA2D1,PTBP2,SLC16A4,LRBA,MAGI1,C4orf33,HECTD1,IQCK,SLC4A8,IGDCC3,NCOR1,CLIP3,PHF14,TCAF1,TBC1D5,KIAA0586,JAKMIP2,DDX46,CASP8AP2,KLHL5,NSRP1,CORO2B,ZNF605,HIGD1B,C15orf41,TCERG1,CIT,SMAP1,KIF2A,HECTD2,TM6SF1,MYO5A,NEK1,SMIM11A,GPR137C,FAM98B,DIRAS2,ANKHD1,STRC,FAM184A,RBBP6,REV3L,CLIP1,SAFB,CCDC88A,BDP1,SOX11,NEK4,SYNE2,DICER1,STXBP4,ZNF23,ZNF184,GAL3ST3,HNRNPA3,NETO2" Coexpression Atlas GSM605837_500 "Myeloid Cells, DC.8-4-11b-.Sp, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Spleen, avg-2" "Immgen.org, GSE15907" 1.26E-06 6.12E-03 9.09E-06 8.24E-05 69 375 "FMNL2,PTCHD1,ALCAM,FGD2,CASK,ATP1A3,ADAM23,ST3GAL5,DDR1,CD86,CHN2,B4GALT6,LY86,CSF1R,CST3,USP6NL,CYBB,DOCK4,HDAC9,MYADM,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,TLR7,SIRPB1,OLFM1,FGFR1,GATM,GCNT2,RAB30,ADAP1,GSN,FRMD5,IRF8,LRRC25,JAK2,KIT,L1CAM,LIFR,ADAM11,MEF2C,MYO5A,MYO9A,RASGEF1B,PTK2,MARCH1,PID1,C1orf54,ROGDI,RGS12,SNX22,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,RGL1,SULF2,ADGRL3,KIAA0930,NPL,TRIO,TRPM2,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.29E-06 6.26E-03 9.28E-06 8.41E-05 27 98 "AXIN2,PCDH10,SYT13,CDC14B,INSYN2B,RUNX1T1,CBLN1,DCLK1,CRLF1,DLX1,TMEM132C,FREM1,GNG4,SYNPO,PPM1L,ZFHX4,SALL1,FRMPD1,LIMCH1,SOX11,SYNE2,TCF4,KAT6B,TRPS1,WNT7A,KCNAB1,FRMD6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.34E-06 6.52E-03 9.66E-06 8.76E-05 65 347 "ALCAM,CCDC146,CADPS,BMP7,CALM1,SPAG9,PRC1,SEPT7,CDO1,IGDCC3,NECTIN3,SGSM2,CHRDL1,DTNA,EEF1D,FAM13A,ADGRV1,FAM198B,FDFT1,FGFR3,SMC2,PDLIM5,LNX1,CFAP126,ITGA7,SMAD1,MAP6,MEST,KITLG,MSI1,MXI1,NELL2,PDE3A,ENPP2,PLCL1,PLTP,LRRN3,VSTM2L,HYDIN,PTX3,ZMAT4,RFX2,RFX3,NEK11,SALL1,SCN7A,HES6,PUF60,ARX,EPC1,LIMCH1,MYO16,MYCBP2,SPART,ITPRID2,SULF2,SYNE2,TCF12,CCDC173,DNAH7,TMPO,TRPS1,PPIL6,TRIM9,IFT88" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_200_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.47E-06 7.14E-03 1.06E-05 9.57E-05 30 116 "GALNT13,RNF150,C1QTNF3,ALCAM,DPP10,DOCK11,IL33,LDB2,RASSF2,EBF1,EDN3,SEMA3D,TMTC1,IQGAP2,GGT5,GUCY1B1,RASSF8,IFI16,KCND2,NOVA1,RELN,FAT4,CSRNP3,SCN7A,ST8SIA1,NEK4,PCDHB9,TLR4,PCDH20,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_500 DevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.50E-06 7.29E-03 1.08E-05 9.76E-05 70 384 "USP31,ADRB2,HECW2,ADGRF5,NRP2,GPR146,LDLRAD4,CA8,LDB2,CD86,CD38,MAP4K4,LY86,RBM39,CRMP1,HAPLN1,CSF1R,PPP1R16B,CYBB,ELMO1,SEZ6L2,EDNRB,EPHB1,IGSF6,F8,DLC1,FCGR1A,FLT1,FYB1,GATM,PCDH17,GGTA1P,LYVE1,NCKAP1L,ICA1,IRF8,IFI16,LMO2,PIK3AP1,TM6SF1,MEF2C,MEIS2,MSR1,MYO7A,P2RY13,NCF2,RELN,PTPRB,TMEM255A,MAPK12,SGK1,ST8SIA1,SLA,PREX2,SAMSN1,THSD1,TAL1,KLHL4,ARHGAP9,TEK,TLR4,ERCC6L2,NPL,VAV1,WIPF1,PLD4,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.51E-06 7.35E-03 1.08E-05 9.83E-05 21 66 "THSD7A,EBF1,EPB41,NRN1,TUBB3,STMN2,GRIA2,GRIK5,INSM1,MAP2,TAGLN3,NNAT,SCHIP1,MEG3,RTN1,SEPT3,ZEB1,TCF12,RGMB,TSPAN11,CELF4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K1 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.58E-06 7.69E-03 1.13E-05 1.03E-04 87 510 "METAP1D,ADCY8,SLC24A4,KIAA1324,OSBPL6,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,DGKG,TIAM2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,ARMCX1,PTK2B,FCGRT,TPK1,DLL3,ABLIM2,FYB1,GAA,GHDC,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,ICA1,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,TCEAL5,NPR2,PDE4D,PLCL1,TRHDE,SDK2,PILRA,PRKAR1B,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,MORC4,PRIMA1,STK32B,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,ASAP3,ARHGAP26,IQSEC2,ADGRL3,FAM189A1,LRRC24,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.60E-06 7.76E-03 1.14E-05 1.03E-04 51 251 "KDM5D,SEMA7A,GAS7,TMEFF1,CADPS,ATP1A1,DST,ST3GAL5,SYNJ2,RGN,CDO1,MAGED1,SCRN1,RCAN1,DTNA,DTNB,MRO,REEP2,PTK2B,SUCO,CAMKK2,GATM,PPARGC1A,GPR37,SYTL4,NCOA7,MAN2A2,MSI1,NRBP2,SLC10A4,MTRF1L,RASGEF1B,PTCH1,PTPRE,SH3TC2,DUSP15,RNASE1,ROBO1,GLDN,RPS6KA2,MRAS,KIF21A,ST6GAL1,SPP1,ADHFE1,TACC1,TIAM1,BEX4,SLC38A1,ADAMTS9,NETO2" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.60E-06 7.77E-03 1.14E-05 1.03E-04 27 99 "CASK,RNF182,RUNX1T1,CLIP3,GSDME,ALKBH8,EDNRB,PRMT5,MEX3B,STMN2,LIFR,LRRN3,ROBO2,CSRNP3,WDR37,ZKSCAN3,RBM26,RGL1,SULF2,KLHL4,CUX2,CLASP1,ASXL3,TPM1,TRIO,WNT7A,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.71E-06 8.29E-03 1.22E-05 1.10E-04 62 328 "ARHGAP20,RASL11B,TMEM108,MYRF,KALRN,CBLN1,SLIT2,CNTFR,AKAP5,CLIP3,VCAN,BOC,TIAM2,DNM1,TSPAN5,EDNRA,C8orf37,AMOTL2,MEX3B,FLNC,NSG1,TRAF3IP2,DENND2A,FREM1,CSDC2,GHR,GLI2,GUCY1A1,TCEAL6,NKD1,MAP2,MATN2,MEIS1,MEIS2,TCEAL5,ZC3H12B,NEFM,NNAT,NME4,PIK3R1,PCDH18,LAMA1,PTN,RADX,RIC8B,ROBO2,MEG3,KCNIP1,CLIP1,PKNOX2,ZC4H2,SULF2,KLHL7,ASXL3,TPM1,TRPS1,SSBP2,PLEKHH2,VSNL1,ZFP37,ZNF184,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.74E-06 8.43E-03 1.23E-05 1.12E-04 38 166 "OGT,LRCH2,LCORL,PDE8B,INSYN2B,AKAP7,PHF14,DOCK2,TSPAN5,FGF11,NSG1,SESN1,TCEAL6,IGF1,NKD1,LAYN,NEXMIF,NPR2,ENPP2,TATDN3,MAPK9,GDPD2,CNTLN,PTPRO,FAT4,RNASEL,SEMA6D,PRCD,STUM,ATF7IP,PDZD2,LHPP,ADAMTS17,TCF12,SZT2,DCBLD1,LYPD6,FRMD6" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_200 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.74E-06 8.43E-03 1.23E-05 1.12E-04 38 166 "ADD1,ARHGAP20,LTBP4,PKP4,BACH1,RUNX1T1,DCLK1,SLIT2,COL4A5,RBM39,RIPOR2,ZC3H11A,EDNRA,EIF4G1,ELN,EPB41L2,LRRC17,GAD1,GLUL,LPAR4,CHIC1,MEIS1,MEIS2,MMP16,NFIX,PCDH9,NALCN,C1orf54,LGI2,TMLHE,MEG3,ARX,SYNE2,CBX5,SSBP2,UBE3A,FLRT2,ADAMTS9" Coexpression Atlas GSM399442_500 "Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2" "Immgen.org, GSE15907" 1.74E-06 8.45E-03 1.23E-05 1.12E-04 75 422 "ACHE,FMNL2,ADCY6,ZNF608,OSBPL1A,CC2D2A,AMPD2,CDC42BPA,MYOM1,DST,PRC1,ABCG2,MAGED1,ZNF521,GDA,CYBB,GPRASP1,ARHGAP32,DGKG,PLXNC1,MTSS1L,EYA1,MED12L,NBEA,IQGAP2,GATM,GCNT2,TUBA8,ADGRA3,GRB10,PARD3B,PRDM5,GUCY1A1,IRAK3,HLF,HP,ICA1,IL12A,ITGAM,KIT,STXBP5,STMN1,LMO2,MEF2C,MEIS1,SAMD14,MYCN,P2RY13,NFIX,NPR2,OCRL,P2RY1,PILRA,PRODH,DEF8,CNTLN,RIPOR1,ZNF532,TCP11L1,PEAR1,ARHGEF40,SLC14A1,TET1,ANKRD28,DMXL2,TEK,CBX5,BHLHB9,TNS1,NPL,STXBP4,SSBP2,VIPR2,ZBTB38,PLSCR4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.74E-06 8.45E-03 1.23E-05 1.12E-04 75 422 "METAP1D,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,LDLRAD4,CAMK2A,KCNAB3,CCPG1,VAX2,CRYBB1,CSF1R,TIAM2,DRP2,SNX29,TMTC1,RASA4,ARMCX1,PTK2B,DLL3,ABLIM2,FYB1,GAA,GHDC,TMEM8B,GHR,LYVE1,GNG4,ADAP1,GUCY1B1,TCEAL6,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,DEF8,ZCWPW1,ZNF493,ZMAT4,DUSP15,PRIMA1,LRFN5,MRAS,ASAP3,IQSEC2,ADGRL3,FAM189A1,LRRC24,KCNE5,EML6,LAMP5,CADM2,DNAH10,DPF3,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.76E-06 8.54E-03 1.24E-05 1.13E-04 80 459 "ABHD6,SLC24A4,HECW2,KIAA1324,SMIM17,SRPX,CEP126,ARHGAP20,MARCH4,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,LDLRAD4,CAMK2A,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,DGKG,TIAM2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,DLL3,ABLIM2,FYB1,TMEM8B,GHR,LYVE1,NTNG2,GNG4,GUCY1B1,ICA1,LRRCC1,SCIN,KLHL23,GPR155,MID1,MYH3,NEXMIF,TCEAL5,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,PRIMA1,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,ASAP3,CCDC92,ARHGAP26,IQSEC2,NKAIN2,ADGRL3,FAM189A1,KCNE5,CADM2,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_500 dev gonad_e13.5_M_DevVasTestis_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.85E-06 8.97E-03 1.30E-05 1.18E-04 76 430 "NCKAP5,HECW2,ADGRF5,SPARCL1,SEMA6A,SEMA7A,APBB2,APOC1,SHROOM2,DOCK11,NRP2,CBLN1,LDB2,SCARB1,CD38,MS4A7,ABCG2,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,CYBB,DOCK4,ARMCX2,ELMO1,EBF1,EDNRB,PLXNC1,PLEKHA1,CALCRL,RASGRP2,FAM198B,ACSL4,DLC1,FLT1,AFF2,PDLIM5,FYB1,FYN,IQGAP2,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,MAP4K5,NCKAP1L,ELOVL5,HMGCR,ICA1,KIT,LMO2,LSS,TM6SF1,MEF2C,LAYN,NPY,RASGEF1B,SNRK,PTPRB,TMEM255A,C1orf54,ROBO2,SEMA6D,PREX2,LIMCH1,PEG10,THSD1,KLHL4,TEK,VSNL1,STOX2,NAV3,FAM13C,DOCK8" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.85E-06 8.98E-03 1.30E-05 1.18E-04 22 72 "SYT13,VAT1L,ARHGEF7,LDB2,SEPT7,CHGB,NCOR1,ARHGAP32,EARS2,SEZ6L2,STMN2,CELF5,LSAMP,TMOD2,PPP2R2B,PTN,SNAP25,PEG10,SEPT3,VGF,TRIM9,CELF4" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.88E-06 9.11E-03 1.32E-05 1.20E-04 53 266 "FMNL2,KLHL13,PPP4R4,NUMB,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,RASGRP1,TMEM35A,EMX2,NRN1,JKAMP,GALC,GLUL,PACSIN2,INPP1,KCND2,KLHL23,KITLG,AFF1,MYO9A,SLC11A2,NUCB2,SERPINI1,PIK3C2A,PPP3CC,GDPD1,PTPRG,ZFHX4,TNFRSF19,STUM,RASA3,FRMPD1,SLC4A3,SNCA,KDM3A,UHRF1BP1L,ARHGAP26,ADGRL3,SZT2,DOCK9,DNAH7,ACTR6,PCDH20,ZNF23,ELFN1,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.99E-06 9.67E-03 1.40E-05 1.27E-04 21 67 "PCDH10,PCDHGB4,ADGRB1,HIP1R,SEPT7,CCDC144A,TAOK3,CSPG5,PCDH17,STMN2,GRIA2,GRIK5,HBA1,KCND2,NOVA1,PCDH9,PTN,MEG3,RTN1,CELF4,ANKS1B" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.08E-06 1.01E-02 1.46E-05 1.32E-04 52 260 "FMNL2,KLHL13,PPP4R4,NUMB,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,TMEM35A,EMX2,MTSS1L,GALC,DHRS4,GRIK5,PACSIN2,SHISA6,KLHL23,AFF1,MYO9A,SLC11A2,NUCB2,SERPINI1,PIK3C2A,PPP3CC,PTPRG,REV3L,ZFHX4,HUNK,RASA3,ST8SIA1,SLC4A3,SNCA,UHRF1BP1L,ST5,ADGRL3,DOCK9,OBSL1,CCDC173,DNAH7,ZFPM2,ACTR6,KAT6B,ZNF23,ELFN1,DPF3" Coexpression Atlas GSM605883_500 "Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 2.09E-06 1.01E-02 1.46E-05 1.32E-04 72 402 "ADRB2,MTUS1,ABCD2,AMPD3,APOC2,CASK,ATP1A3,BACH1,ST3GAL5,SCARB1,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,CST3,CYBB,MYADM,LONRF1,DGKG,TIAM2,RCAN1,ABCC5,EBI3,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FLT1,CAMKK2,TPPP3,FYB1,GCNT2,ADAP1,SLC2A6,IRAK3,HP,IFI16,LRRC25,IL6R,ITGAM,L1CAM,LIFR,PIK3AP1,MEF2C,NCF2,PFKFB4,PLTP,PILRA,DRAM2,PRKAB2,PTPRE,PID1,C1orf54,RPS6KA2,LRRK2,RTN1,SEC14L1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,SAMSN1,TLR4,TRPS1,EVI5,PLD4,NLRP3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.09E-06 1.01E-02 1.46E-05 1.32E-04 75 424 "KLHL13,ARHGAP20,PPP4R4,TMEM108,MYRF,CACNA2D1,CALB1,RUNX1T1,CBLN1,DCLK1,SLIT2,CNTFR,ZNF521,HAPLN1,CLIP3,VCAN,PLXNA4,DOCK4,DAPK1,DNM1,DRP2,EDNRA,PLXNC1,EMX2,NRN1,ABCA8,FLNC,AFF2,NOP56,ZMAT1,FREM1,GHR,GUCY1A1,TCEAL6,NKD1,KCND2,KLHL23,MATN2,MEIS1,MEIS2,KITLG,MMP16,TCEAL5,NEFM,NNAT,PDE3A,SERPINI1,PIK3R1,PCDH18,PTN,TMEM255A,RNASEL,ZFHX4,ROBO2,HUNK,CCDC112,DZIP1,SLC4A3,KDM3A,UHRF1BP1L,PEG10,ADGRL3,KLHL4,CUX2,ZFPM2,ACTR6,ASXL3,TRPS1,FLRT2,PLEKHH2,PCDH20,ZNF711,LYPD6,WNK3,DPF3" Coexpression Atlas ratio_ECTO_vs_SC_1000_K3 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 2.11E-06 1.02E-02 1.47E-05 1.34E-04 82 476 "ABHD6,SORCS2,APLP1,CA4,CABP7,CDH2,NOG,LHX2,CNTFR,NRG2,FAM171B,SEC31B,HAPLN1,BOC,LYPD1,KIF19,CDON,EMX2,NCALD,CLVS1,TMEM132C,DENND2A,GPR162,DCLK2,ZNF491,TMEM240,INSM1,LRRTM1,NME9,CDH20,CLEC18A,MAP2,MAP6,MEIS2,SAMD5,TAGLN3,RTL5,NPY,IGSF11,CNTN3,PAX6,PRTG,ENPP2,SDK2,MAPK10,STRC,TMEM255A,PRRT2,ZFHX4,KLHDC8A,MELTF-AS1,HSD11B1L,SMPD3,ARX,PKNOX2,GKAP1,DMRTC1,SOX3,LMO3,CLSTN2,SSPO,PCDHGB6,PCDHB10,PCDHA6,PCDHA3,DICER1-AS1,ASXL3,NR2E1,RIMBP2,PPIL6,CLEC2L,ZIC1,ELFN1,EMX2OS,CRB2,MKRN3,DPYSL5,ADAMTS9,DNAH10,FAM182B,FAM181A,PRRT4" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k1 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.14E-06 1.04E-02 1.49E-05 1.35E-04 25 89 "FAM135A,CASK,RNF182,CDH2,NSL1,PYGO1,EBF1,ADGRV1,UBE2E3,CHL1,HAS2,LSAMP,MYO5A,PCDH8,CNTLN,CRTAC1,FIGN,SALL1,DZIP1,WDR37,CXXC4,PCDHB3,ASXL3,MKRN3,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.14E-06 1.04E-02 1.49E-05 1.35E-04 25 89 "ARHGAP20,MYRF,AKAP5,ZNF521,BOC,DPYSL2,TSPAN5,NSG1,TRAF3IP2,ELOVL5,IGF1,NKD1,MAP2,MATN2,MEIS1,LAYN,NNAT,PCDH18,FAT4,TSPY26P,RNASEL,MEG3,CCDC112,SEMA6D,PEG10" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.16E-06 1.05E-02 1.51E-05 1.37E-04 31 124 "PLEKHH1,EPB41L5,PROM1,CNTFR,IGDCC3,FAM169A,RIMS2,JAKMIP2,PLXNC1,ACSL4,FHL1,FUT9,GABRB3,TCERG1,TOX3,MAP7D2,SOX21,USP51,KIT,KTN1,NOVA1,FAM98B,SEMA5B,ELOVL2,EML5,CCDC40,KIF21A,NEK4,ANKRD28,RBFOX3,KCNT2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.26E-06 1.10E-02 1.57E-05 1.42E-04 15 38 "DPP10,CADPS,CACNA1B,CHGB,GRIN3A,STMN2,MAP4,NEFM,CLDN11,NALCN,MAPK10,PRPH,RGS4,RTN1,SNAP25" Coexpression Atlas ratio_SC_vs_ECTO_2500_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 2.29E-06 1.11E-02 1.59E-05 1.44E-04 132 865 "SYN3,TMEM132B,ADCY8,GALNT13,RNF157,UNC5A,PWWP2A,PTCHD1,KLHL13,OSBPL1A,GPRASP2,PDZD4,LRFN1,NT5C3B,PPFIA3,CCDC74A,CARMIL3,CALB1,CBS,CLDN10,DCLK1,CHRNA4,FAM189A2,FAM19A5,CCDC151,CRYBB1,C1QL2,LRRC3B,GALNT9,VCAN,RIMS4,SEC14L5,EARS2,KIF26A,LONRF1,KCTD8,TMEM170A,BRINP1,JAKMIP2,DGCR5,ALKBH8,PARD6A,CHRDL1,RAB39B,HS3ST2,WDPCP,EBI3,AASS,TENM1,MRPL10,ETV1,PIPOX,TBC1D16,PPP1R1B,OLFM1,POLR1B,SPSB4,MAD2L2,HPCAL4,FLT1,NOP56,SYT3,SPECC1,CSPG5,MEGF11,MEGF10,HRASLS5,GABRB3,IGSF5,GCK,GNG4,GRIN2D,LINGO1,HNF4G,CPT1C,LRRC75A,SHISAL1,ZIC5,KNDC1,C2CD4C,KCND2,KCNN1,KCNN2,KHK,KIF5A,CAMK2N2,SFXN5,MYCN,FXYD7,NPTX2,JAKMIP1,PPP2R2B,PPP2R2C,PRODH,TMEM145,NKAIN1,SLC25A48,ZMAT4,TSPY26P,RET,RORB,MRAP2,STX1B,PREX2,SEPHS1,OGDHL,SNRPN,HECW1,STAC2,SEPT3,NECAB1,RHBDL3,SYN1,ARC,SYN2,COBL,TACR1,KLHL4,CCDC173,CHST8,ENHO,ANKRD24,IL34,UGT8,MGAT5B,VSNL1,RBFOX3,SLC38A1,GAL3ST3,ITM2C,NETO1,ZNF30" Coexpression Atlas ratio_EB_vs_SC_1000_K5 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.36E-06 1.15E-02 1.63E-05 1.48E-04 74 418 "PCDH19,SORCS2,PCDH10,LGR5,TTLL9,MYRF,CABP7,NOG,LHX2,CNR1,CNTFR,HAPLN1,PYGO1,LYPD1,DUSP9,EDN3,EDNRA,EMX2,ERBB4,NCALD,CLVS1,TMEM132C,ZMYND10,PSD2,CPLX2,FREM1,PCDH17,GHR,CCDC184,STMN2,GRIA2,C1QL4,GUCY1A1,C2orf72,NKD1,INSM1,LRRTM1,NME9,CDH20,CLEC18A,MAP6,LRP1B,TAGLN3,MYT1,NTRK2,PAX6,PDZRN4,LRRN3,PRPH,ZFHX4,ROBO2,RTN1,SMPD3,TRIM67,DMRTC1,SNAP25,ANKFN1,CLSTN2,SST,PCDHGB6,DNAH7,ASXL3,RIMBP2,DOK6,LRRC24,PPIL6,ZIC1,EMX2OS,CRB2,ADAMTS9,DNAH10,FAM13C,FAM181A,PRRT4" Coexpression Atlas gudmap_developingKidney_e15.5_Medullary collecting duct_1000 DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.36E-06 1.15E-02 1.63E-05 1.48E-04 122 786 "RALGAPA1,METAP1D,ADORA1,AP2A2,OSBPL6,AMPD3,OGT,APC,EPB41L5,SFMBT2,CASK,ARHGDIG,PDE8B,ATP1A1,RGS11,BMP7,SCAPER,CA4,CALB1,HIP1R,USP2,LRRFIP1,CBARP,B4GALT6,CLCN3,FAM149A,COL4A5,AHCTF1,SLC35F1,ENTPD4,RBM39,CRYM,IPCEF1,VCAN,CNTNAP2,CTH,AIF1L,MFAP3L,DDX46,PDCD6IP,SNX29,HIPK3,SEMA3D,EIF5,TENM1,EIF1,EMX2,ENO2,VPS13B,EPB41,SLC43A2,F5,RACK1,PRKAG2,SUCO,FOXO3,ANKFY1,APOPT1,RASL10A,CAMKK2,GALC,RAPGEF6,IQGAP2,IGSF5,PPARGC1A,CCDC184,GRB10,DIDO1,GSTT2,PADI2,ICA1,SCIN,SLC35G1,KCNJ16,KIF2A,L1CAM,LIFR,AQP11,MBP,CHIC1,SCAMP5,MKLN1,MYO6,VWA2,PIK3C2A,RETREG1,JAKMIP1,PLXNB1,ANKRD16,STRN3,MBOAT7,KANSL1,PTPRO,ZDHHC14,DPF2,REV3L,EMID1,MEG3,SCN8A,HKDC1,NAPB,MYCBP2,SPP1,ATP10B,STX1A,PRRC2C,DNMBP,MGRN1,WSCD1,OBSL1,ERCC6L2,RGMB,SSBP2,RPRM,UGT8,PDIA2,ZNF23,LYPD6,TMEM178A,SEMA3B,FIP1L1,DOCK8" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_cfr-2X-p05 Pluripotent Stem Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.40E-06 1.16E-02 1.65E-05 1.50E-04 125 810 "TMEM132B,ADD2,OSBPL1A,WDR35,SEMA6A,APLP1,VAT1L,ATP1A3,ADAM15,BLM,PROM1,PTBP2,CBR1,CLDN10,LDB2,DCLK1,MAGI1,CDO1,UBE2L6,FOXN3,CHN1,PCYT1B,IGDCC3,NECTIN3,AKAP12,CRMP1,CRYM,RIMS4,FAM131B,BRINP1,JAKMIP2,ALKBH8,SACS,CHRDL1,DPYSL2,DNAJB6,FARSB,EDIL3,EDNRB,AASS,ERBB2,PIPOX,ACSL4,FDFT1,PPP1R1B,ZNF589,OLFM1,POLR1B,MAD2L2,FHL1,SEMA4D,FLT1,NBEA,NSG1,MPP6,MEGF10,IQGAP2,SESN1,DBF4,GLI2,GNG4,GRIK5,KAT7,SOX21,LINGO1,PSIP1,HMGCR,C9orf129,CPT1C,ZIC5,RBPJ,KCNN2,KIF5A,LSS,SCAMP5,MID1,MMP17,MPP2,MYCN,NEFM,NELL2,NPTX2,PCDH18,PSAT1,EPB41L4B,FSD1,PPM1B,PPP2R2B,PKIA,GDPD2,PTN,NKAIN1,ROBO1,TUNAR,CCDC112,SEPHS1,CCDC88A,OGDHL,SNRPN,PDZRN3,TRERF1,SP4,SPP1,UNC5B,ZNF423,PHLDB1,SEPT3,STXBP1,KLHL7,RHBDL3,ARHGEF9,SYT1,COBL,MTCL1,WSCD1,TCF4,ENHO,RELL2,UGT8,VSNL1,TCEAL7,ZFAND5,SLC38A1,GAL3ST3,PDSS2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.40E-06 1.17E-02 1.66E-05 1.50E-04 42 194 "VAT1L,CADPS,CNTFR,CRMP1,CLIP3,SCRN1,EDNRA,LRRC17,EYA1,TUBB3,NSG1,SYT17,IGSF5,GFRA2,FREM1,GLI2,GNAO1,STMN2,ACOT7,L1CAM,MATN2,TAGLN3,NEFM,NELL2,NFIX,SLC10A4,FXYD1,PMP22,NKAIN4,MAPK10,PRPH,MASP1,TMEM255A,RET,RTN1,SNAP25,SST,SULF2,ADAMTS17,SYT1,CUX2,UCHL1" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000_k5 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.41E-06 1.17E-02 1.66E-05 1.51E-04 40 181 "LGR5,PLA2G4C,PDE8B,ASPA,INSYN2B,SYNJ1,SCAPER,CALB1,CNR1,GREB1,DYNC1I1,DRP2,DTNB,DNAJB6,RASGRP1,ATP6V1H,GATM,AIFM3,MAP7D2,KCND2,MYO5A,NEXMIF,GLIPR1L2,SERPINI1,JAKMIP1,PPP2R5E,PRCD,FNIP1,TNFRSF19,HSPA4L,CPEB3,SYBU,SYNE2,SLC37A2,ANKRD12,DMXL2,TBC1D15,ZNF23,REEP1,PHTF2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_500 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.42E-06 1.17E-02 1.66E-05 1.51E-04 76 433 "KDM5D,HECW2,KLHL13,ARHGAP20,PPP4R4,TMEM108,MYRF,CALB1,CBLN1,DCLK1,MAGI1,CNTFR,AKAP5,ZNF521,HAPLN1,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,DNM1,CPEB2,DRP2,EDNRA,SEMA3D,MRO,PLXNC1,EMX2,MTSS1L,FAM198B,PTK2B,FLNC,DENND2A,FREM1,CSDC2,GHR,PPARGC1A,GLI2,GPR37,BVES,GUCY1A1,SHISA6,KCND2,KLHL23,MATN2,MEIS1,NEFM,NME4,PFKFB3,SERPINI1,PCDH18,RASGEF1B,PTN,TMEM255A,RBBP8,RADX,ROBO1,ROBO2,MEG3,HUNK,RASA3,ST8SIA1,SLC4A3,PKNOX2,KDM3A,UHRF1BP1L,ST5,ADGRL3,ZFPM2,ACTR6,ASXL3,BEX4,ZNF711,WNK3,DPF3,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.43E-06 1.18E-02 1.67E-05 1.52E-04 73 411 "RNF157,ADORA1,PCDH19,DOC2A,AMPH,BMP7,CA4,CA12,CALB1,CAMK2B,TBRG4,CRLF1,FAM189A2,PICK1,CRYM,KIAA0040,GREB1,SNAP91,USP3,DUSP9,HEYL,PCOLCE2,EMX2,EPHB1,EYA1,RACK1,ST3GAL6,FKTN,SLC9B2,SPSB4,FGFR1,PSD2,HVCN1,TRIM16,RASL10A,CGREF1,TVP23A,GALC,IGSF5,BRD8,ADGRA3,DIDO1,PRDM5,HAS2,KCNJ16,CLEC18A,MARK1,TM6SF1,MID1,PTOV1,VWA2,NPY,NPTX1,OXTR,PRTG,PDE1C,PLXNB1,ANKRD16,LAMA1,NKAIN1,GAL3ST4,DUSP15,EMID1,SALL1,MAPK12,SCN8A,SH3BGR,DHX30,HEY1,CA14,TMEM178A,URM1,PCBP4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_100 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.44E-06 1.18E-02 1.67E-05 1.52E-04 24 84 "ARHGAP20,BACH1,RUNX1T1,SLIT2,PLAA,RBM39,ZC3H11A,EDNRA,EIF4G1,EPB41L2,LPAR4,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,TMLHE,MEG3,ARX,KLHL4,CBX5,SSBP2,FLRT2,ADAMTS9" Coexpression Atlas GSM538213_500 "B cells, B.T1.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23-, Spleen, avg-3" "Immgen.org, GSE15907" 2.46E-06 1.20E-02 1.69E-05 1.53E-04 65 353 "ADRB2,ZNF608,TXNDC16,FGD2,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,RUBCN,CYBB,HDAC9,MYADM,RIPOR2,ARHGAP24,GUCD1,SLC12A6,EBF1,SNX29,RASGRP1,FRY,KCTD3,SRPK3,TLR7,CHST15,HVCN1,ACSS1,MALT1,RAB30,IRAK3,BACH2,IRF8,IL12A,KTN1,LIFR,PIK3AP1,GPR155,MEF2C,MX1,NUCB2,MINDY2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,ZDHHC14,LRRK2,RASA3,PPM1E,ST6GAL1,LMBRD1,SLC37A2,KIAA0930,CYB561A3,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 2.50E-06 1.21E-02 1.71E-05 1.55E-04 84 493 "ABCF1,KDM5D,PCDH19,MAGEE2,APOC2,CDK10,ARRB2,BBS2,MPDZ,ZNF599,PROM1,CA12,PTBP2,CRLF1,DIS3L,PCYT1B,SLC4A8,IGDCC3,CRYM,KIAA0586,JAKMIP2,CDON,DUSP9,KLHL5,EMX2,EPB41,ETV1,NSRP1,TMEM132C,ACSL4,FDFT1,FGF12,HPCAL4,SMC2,ST6GALNAC3,FYB1,C15orf41,ZNF276,TXNL4A,COPS8,PCLO,CIT,GSN,SYNPO,IGF1,LAMA2,LSS,GPR155,MBNL1,SRSF12,MID1,NFIX,NNAT,OPA1,PCSK5,PDE3A,PILRA,DIRAS2,ELOVL2,STRC,REV3L,KIF7,ZFHX4,CLIP1,CASC3,KIF21A,PREX2,LIMCH1,SPATA7,BDP1,SOX11,SYNE2,TAF9,TIAM1,ASXL3,BHLHB9,AMACR,TRPS1,CA14,ZKSCAN5,USP1,LAMP5,HNRNPA3,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K5 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.56E-06 1.25E-02 1.75E-05 1.59E-04 46 221 "ABR,KIAA1211,PCDH19,TXNDC16,OGT,MAGEE2,MPDZ,PROM1,HAP1,SLC4A8,JAKMIP2,EMX2,CLVS1,ACSL4,FGF12,FGFR3,MAD2L2,EVL,ZNF605,GABBR1,GAD1,PCLO,RNFT2,INSM1,KCNH2,SHC3,LRP12,MAGEL2,ELOVL2,PEX2,RAD51D,GTDC1,ROBO2,CCDC25,SGSM1,CASC3,KIF21A,SNAP25,KIF13A,ERC1,SYNE2,COBL,SIK3,BHLHB9,NHSL1,SENP7" Coexpression Atlas BM Top 100 - ventral tegmental area BM Top 100 - ventral tegmental area Body Map 2.61E-06 1.27E-02 1.78E-05 1.61E-04 21 68 "CARNS1,SYT13,VXN,SYNGR3,GABRG2,GAD1,GPR37,STMN2,KCNJ16,MAP4,MBP,NEFM,NEFH,QDPR,TMEM255A,SNAP25,SNRPN,SPP1,SYT1,PRR18,P2RY12" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.63E-06 1.28E-02 1.79E-05 1.63E-04 36 156 "NDRG2,ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,RUNX1T1,ARHGEF25,CBLN1,SLIT2,SNCAIP,VCAN,RIPOR2,ARHGAP24,ARMCX2,EDNRA,HEYL,EGFR,LRRC17,DLC1,GFRA2,FREM1,GLI2,GUCY1A1,GUCY1B1,LAMA2,PCDH9,FXYD1,PLTP,PMP22,SH3KBP1,LRRN3,LAMA1,ROBO2,SULF2,STOX2" Coexpression Atlas GSM538219_500 "B cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 2.66E-06 1.29E-02 1.81E-05 1.64E-04 66 361 "ZNF608,TXNDC16,FGD2,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,PPP1R16B,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,FRY,EGR3,SRPK3,DENND4A,TLR7,PTK2B,CHST15,HVCN1,IGSF5,MALT1,RAB30,DCLK2,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,GPR155,MEF2C,MYO5A,NCF2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,LRRK2,SH3BP2,ST6GAL1,SLC4A3,LMBRD1,ARHGAP26,SLC37A2,TCF4,CYB561A3,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 2.67E-06 1.29E-02 1.81E-05 1.64E-04 73 412 "METAP1D,ADCY8,SLC24A4,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,CPNE5,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,IL33,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,TIAM2,DRP2,SNX29,TMTC1,RASA4,ARMCX1,PTK2B,ZMYND15,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,TCEAL6,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ZCWPW1,ZNF493,ZMAT4,MORC4,PRIMA1,STK32B,LRFN5,MRAS,SGK1,ASAP3,IQSEC2,FAM189A1,LRRC24,KCNE5,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_100_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.85E-06 1.38E-02 1.93E-05 1.75E-04 17 48 "BACH1,RUNX1T1,SLIT2,PLAA,ZC3H11A,EIF4G1,EPB41L2,LPAR4,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,FLRT2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K1 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.94E-06 1.43E-02 1.99E-05 1.81E-04 80 465 "METAP1D,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,IL33,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,TIAM2,DRP2,SNX29,TMTC1,RASA4,ARMCX1,PTK2B,HPCAL4,DLL3,ABLIM2,FYB1,GAA,GHDC,TMEM8B,GHR,LYVE1,GNG4,ADAP1,GUCY1B1,ICA1,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,DUSP15,PRIMA1,STK32B,LRFN5,MRAS,SGK1,ASAP3,ARHGAP26,IQSEC2,ADGRL3,FAM189A1,TNS1,LRRC24,KCNE5,LAMP5,CADM2,DNAH10,DPF3,PRRT4" Coexpression Atlas GSM854273_500 "Myeloid Cells, DC.103-11b+F4/80lo.Kd, CD45+ CD11c+ I-A/I-E+ CD11b+ F4/80lo, Kidney, avg-3" "Immgen.org, GSE15907" 3.01E-06 1.46E-02 2.04E-05 1.85E-04 72 406 "FMNL2,RNF150,PTCHD1,ALCAM,FGD2,CASK,ATP6V0A1,ST3GAL5,CD86,CHN2,B4GALT6,ARHGAP22,LY86,GDA,CSF1R,CSF2RA,CST3,CYBB,DOCK4,MYADM,DGKG,DAPK1,EBI3,PLXNC1,RASA4,IGSF6,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,FGFR1,GATM,GCNT2,HPGDS,GSN,IFI16,LRRC25,IL6R,FAM69A,ITGAM,L1CAM,LIFR,LMO2,GPR155,MEF2C,AFDN,MYO5A,RTL5,NCF2,P2RX7,PFKFB4,PLTP,PILRA,PID1,C1orf54,LRRK2,RTN1,DGLUCY,CCDC88A,SLC11A1,TRERF1,SULF2,KIAA0930,TIAM1,TLR4,TRPS1,LAT2,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_500_k1 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.08E-06 1.49E-02 2.07E-05 1.88E-04 22 74 "ADORA1,PCDH19,DOC2A,EPB41L5,CDC14B,KIAA0040,GREB1,SCRN1,HEYL,ST3GAL6,FGFR1,IGSF5,ADGRA3,GPER1,FAM107A,CLEC18A,OXTR,PLXNB1,NKAIN1,EMID1,SALL1,HEY1" Coexpression Atlas BM Top 100 - hypothalamus BM Top 100 - hypothalamus Body Map 3.08E-06 1.49E-02 2.07E-05 1.88E-04 22 74 "CARNS1,CALB1,CALB2,SYNGR3,GABRG2,GAD1,GPR37,STMN2,ARHGAP36,CELF5,KCNJ16,MAP4,MBP,NEFM,NEFH,SERPINI1,SNRPN,SST,SYT1,PRR18,P2RY12,CELF4" Coexpression Atlas Arv_SC-hpx_blastocyst_2500_K2 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 3.17E-06 1.54E-02 2.13E-05 1.93E-04 143 959 "KCNH8,SYN3,TMEM132B,ADCY8,GALNT13,SEMA6A,UNC79,PDZD4,DPP10,RASL11B,KIF1A,CARMIL3,RGS9,GYG2,HAP1,CLDN10,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,FAM19A5,SULT4A1,IGLON5,CABP1,COL9A1,COL9A3,GAL3ST1,IGDCC3,C1QL2,IPCEF1,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,LONRF1,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,CHRDL1,RAB39B,DPP6,SLC25A18,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SPSB4,MAD2L2,HPCAL4,SYT3,CSPG5,TVP23A,MEGF10,HRASLS5,GABRB3,SYT17,SRRM4,TTBK1,TOX3,GNG4,LPAR4,KAT7,SOX21,LINGO1,PSIP1,PADI2,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KIF5A,CAMK2N2,SCAMP5,ADAM22,FXYD7,NLGN3,SEMA5B,PNMA3,PSAT1,NECAB2,FA2H,PPP2R2B,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,LGI2,ZNF532,SALL1,TMEM200C,PPM1E,CNKSR2,SEPHS1,OGDHL,SNRPN,SOX3,NMNAT2,HECW1,SOX21-AS1,SEPT3,NECAB1,ARC,SYN2,COBL,KLHL4,CUX2,FAM189A1,CCDC173,SIRT1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,KCNE5,CA14,TUBB2A,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,TMEM198,DPYSL5,DHX33,CADM2,STOX2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.29E-06 1.60E-02 2.21E-05 2.00E-04 69 385 "METAP1D,ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,VCAN,TIAM2,DRP2,SNX29,TMTC1,RASA4,PTK2B,SEMA4D,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,TCEAL6,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ZCWPW1,ZNF493,ZMAT4,PRIMA1,STK32B,SGK1,ASAP3,DOK5,IQSEC2,FAM189A1,LRRC24,KCNE5,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 3.29E-06 1.60E-02 2.21E-05 2.00E-04 69 385 "EMILIN3,KIAA1324,SRPX,ARHGAP20,CDK10,ADGRB2,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,KCNAB3,CDO1,CRLF1,ABI3BP,ANKRD44,CSF1R,DRP2,RASA4,ELN,LRRC17,FCGRT,TRIM16,TPK1,TVP23A,FYB1,TMEM8B,ZNF276,GNG4,GSN,SYNPO,CREG2,GPR155,MBNL1,SRSF12,TCEAL5,NFIX,NPR2,CNTN3,PDE4D,PLCL1,TRHDE,SDK2,EPB41L4B,PRKAR1B,CNTLN,ACSS3,IQSEC3,ZCWPW1,ZNF493,BEND5,ZMAT4,ZFHX4,LRRK2,DGLUCY,MRAS,SH3GL3,ASAP3,SLC8A1,LIMCH1,PDZRN3,ADGRL3,SATB2,PHF24,SYNPO2,TRPS1,TSPAN11,LAMP5,CADM2,DPF3" Coexpression Atlas GSM538245_500 "Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 3.30E-06 1.60E-02 2.21E-05 2.00E-04 72 407 "FMNL2,RNF150,PTCHD1,ALCAM,SEMA7A,FGD2,CASK,ATP1A3,ADAM23,NRP2,DST,HAP1,CD86,CHN2,B4GALT6,LY86,SLC4A8,ZNF385A,GDA,CSF1R,CSF2RA,CYBB,DOCK4,DAPK1,PLXNC1,RASA4,IGSF6,SIRPB1,OLFM1,ZMYND15,GATM,GFRA2,RAB30,ADAP1,LRRC25,IL6R,ITGAM,JAK2,KIT,ADAM11,ADAM22,MYO5A,NCF2,PFKFB3,PLTP,RASGEF1B,PTK2,PTPRO,MARCH1,PID1,ROGDI,LRRK2,RTN1,ST8SIA1,SLC8A1,CCDC88A,TRERF1,ITPRID2,RGL1,SULF2,ADGRL3,SLC44A1,TIAM1,TNS1,TRIO,TRPS1,LAT2,SPIRE1,SIGLEC10,PLD4,JMJD1C,NLRP3" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k3_1000 dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.30E-06 1.60E-02 2.21E-05 2.00E-04 77 444 "CCDC85A,ADORA2A,ADGRF5,SPARCL1,SEMA6A,APBB2,UPRT,SHROOM2,ARRB1,DOCK11,ADAM15,NRP2,ARHGEF7,LDB2,CD38,ARHGEF2,MS4A7,TAOK2,TMEM184B,MAP4K4,CREM,CRMP1,CSF1R,CYBB,RASSF2,GIT2,DBN1,PITPNC1,EBF1,CALCRL,RASGRP2,STX2,DENND4A,CORO2B,DLC1,FLT1,PDLIM5,TRIM16,PCDH17,GGTA1P,LILRB4,LPAR4,MAP4K5,NCKAP1L,ICA1,LMO2,TM6SF1,MEF2C,MEST,MYO6,PALM,PDE4B,PDE4D,GNG2,DRAM2,SNRK,PTK2,PTPRB,TMEM255A,C1orf54,PREX2,BTBD3,CPEB4,LIMCH1,UNC5B,THSD1,STXBP1,PLCB1,TCF4,DOCK9,TEK,WIPF1,NAV3,FAM13C,DOCK8,JMJD1C,RNF146" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.31E-06 1.61E-02 2.21E-05 2.00E-04 46 223 "FMNL2,KLHL13,PPP4R4,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,TMEM35A,EMX2,PCYOX1,GALC,PACSIN2,SHISA6,KLHL23,KITLG,MYO9A,NUCB2,ETFRF1,SERPINI1,SEMA5B,PPARA,PPP3CC,REV3L,ZFHX4,HUNK,RASA3,FRMPD1,ST8SIA1,SLC4A3,UHRF1BP1L,ST5,SLC37A2,ADGRL3,DOCK9,OBSL1,DNAH7,ACTR6,ZNF23,ELFN1,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.32E-06 1.61E-02 2.21E-05 2.00E-04 15 39 "TMCC3,SYT13,CALB1,CHGB,TMEM35A,NSG1,GNAO1,STMN2,NEGR1,LSAMP,RTN1,PEG10,SEPT3,VGF,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.32E-06 1.61E-02 2.21E-05 2.00E-04 15 39 "SYT13,RUNX1T1,TMEM35A,RCAN2,NSG1,STMN2,CELF5,BEX5,TMOD2,RTN1,SNAP25,PEG10,SEPT3,VGF,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.32E-06 1.61E-02 2.21E-05 2.00E-04 15 39 "PCDH10,CHGB,CNTN1,SPOCK2,BRINP1,TMEM35A,GNAO1,STMN2,GRIK5,MEG3,RTN1,MYCBP2,ERC1,SYT1,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 3.32E-06 1.61E-02 2.21E-05 2.00E-04 15 39 "PCDH10,CHGB,CNTN1,SPOCK2,BRINP1,TMEM35A,GNAO1,STMN2,GRIK5,MEG3,RTN1,MYCBP2,ERC1,SYT1,CELF4" Coexpression Atlas GSM605886_500 "Myeloid Cells, Mo.6C-IIint.Bl, CD115+ B220- CD43- Ly6C- MHCIIint, Blood, avg-5" "Immgen.org, GSE15907" 3.40E-06 1.65E-02 2.26E-05 2.05E-04 71 400 "ADRB2,ALCAM,ABCD2,AMPD3,APOC2,CASK,ATP1A3,BACH1,ST3GAL5,SCARB1,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,CST3,CYBB,MYADM,LONRF1,DGKG,TIAM2,RCAN1,EBI3,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FLT1,CAMKK2,TPPP3,FYB1,GCNT2,GGTA1P,ADAP1,SLC2A6,IRAK3,HP,IFI16,LRRC25,IL6R,ITGAM,L1CAM,LIFR,PIK3AP1,MEF2C,MSR1,NCF2,PFKFB4,PLTP,PILRA,DRAM2,PTPRE,PID1,C1orf54,RPS6KA2,LRRK2,RTN1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,SNCA,SAMSN1,TLR4,TRPS1,EVI5,PLD4,NLRP3" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.74E-06 1.82E-02 2.48E-05 2.25E-04 56 293 "ACTN1,NDRG2,ADCY5,ADORA1,KLHL13,SPARCL1,ALDH7A1,MYOM1,ARHGEF7,DCLK1,NDST3,CABP1,C2CD2,AKAP12,VCAN,RIPOR2,DMD,DMPK,EDIL3,EDNRA,HEYL,CERCAM,NCALD,ETV1,ABCA8,FHL1,CPLX2,IGSF5,TOX3,GP1BB,HSPA1L,SLC6A17,MEF2C,MYH3,NTRK3,FXYD1,PURG,MAPK10,RELN,LAMA1,TMEM255A,FIGN,SALL1,SH3BGR,PPM1E,SLC4A3,ELOVL4,NUDT10,ADAMTS17,CUX2,HIF3A,TPM2,UCHL1,ADAMTS9,KCNAB1,RGS7BP" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500_k5 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.75E-06 1.82E-02 2.48E-05 2.25E-04 28 109 "PKP4,DOCK11,BACH1,SGCE,ZNF445,SRSF11,SLIT2,RBM39,AIF1L,ZC3H11A,EDNRA,EIF4G1,EMX2,EPB41L2,MEX3B,LPAR4,CHIC1,SAMD5,CNOT4,PDPK1,C1orf54,RNASEL,TMLHE,ZC3H13,CBX5,SSBP2,ADAMTS9,SENP7" Coexpression Atlas PCBC_ECTO_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500 PCBC 3.75E-06 1.82E-02 2.48E-05 2.25E-04 84 498 "VAT1L,KIF1A,CA4,CAMK2A,CCK,LHX2,IGLON5,COL9A1,GAL3ST1,NRG2,IGDCC3,HAPLN1,LRRC3B,CNTNAP2,PLCXD3,DGKG,LYPD1,SNAP91,CDON,EMX2,ADGRV1,CLVS1,SPSB4,ATP13A4,IP6K3,AIFM3,PRUNE2,LPAR4,SOX21,GUCY1B1,UBE2QL1,IGFBPL1,CELF5,INSM1,CLEC18A,MAP6,TCEAL5,NELL2,NNAT,NPY,IGSF11,PAX6,PRTG,ENPP2,SDK2,NECAB2,MAGEL2,NKAIN4,LAMA1,ELOVL2,PTPRD,STRC,TMEM255A,PRRT2,ZFHX4,KLHDC8A,TMEM200C,ARX,PKNOX2,DMRTC1,SOX3,SOX15,LMO3,CLSTN2,SOX21-AS1,PCDHA6,PCDHA3,PCDHA2,NR2E1,RIMBP2,CA14,CLEC2L,RBFOX3,ZIC1,KCNT2,EMX2OS,CRB2,MKRN3,DPYSL5,LAMP5,CADM2,GAL3ST3,DOCK8,JPH3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.94E-06 1.91E-02 2.60E-05 2.36E-04 41 191 "KLHL32,SORCS2,SPARCL1,ALCAM,ARHGAP20,LTBP4,CACNA2D1,ISPD,CBLN1,LDB2,HAPLN1,VCAN,PLCXD3,RIPOR2,ARMCX2,EDNRA,HEYL,EGFR,LRRC17,EYA1,DLC1,GFRA2,GLI2,PRDM5,LAMA2,MEF2C,PCDH9,PLTP,SH3KBP1,LRRN3,PTCH1,TMEM255A,ROBO2,ARMH4,PDZD2,ZNF423,SULF2,ARHGEF9,ZEB1,VSNL1,STOX2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.95E-06 1.92E-02 2.61E-05 2.36E-04 37 165 "USP31,TAOK1,APAF1,APC,PHYHD1,BCHE,CACNA2D1,SRSF11,VCAN,DZIP3,MYEF2,HIPK3,CALCRL,ETV1,DLC1,PDLIM5,IQGAP2,PCDH17,GRIA2,HECTD2,CHIC1,MKLN1,MMP16,NCAM2,TMOD2,SETD5,ST8SIA1,NAPB,CLASP2,AGTPBP1,FBXW11,CLASP1,NSD1,ERCC6L2,RGMB,TRPS1,WRN" Coexpression Atlas Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap CCHMC 3.96E-06 1.92E-02 2.61E-05 2.36E-04 48 238 "NDRG3,NDRG2,AGT,SPARCL1,SEPT7,CDH2,ARHGEF6,CST3,ARHGAP32,DBI,EBF1,EDNRA,HEYL,RASGRP2,RASL12,DLC1,FGFR1,HIGD1B,FERMT2,GSN,GUCY1A1,GUCY1B1,KLHL23,KCNK3,LIMS1,MAPT,MAT2A,MEST,MPP2,ENPP2,FXYD1,PCDH18,SEPT4,NKAIN4,C1orf54,EMID1,MEG3,PEAR1,BTBD3,SLC12A2,LIMCH1,PDZD2,TACC1,TNS1,TPM1,VSNL1,TUBA1A,TMEM178A" Coexpression Atlas PCBC_EB_fibroblast_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 4.06E-06 1.97E-02 2.67E-05 2.42E-04 84 499 "AGT,SPARCL1,LGR5,CACNA1G,MYRF,CABP7,CAMK2A,NOG,LHX2,IGLON5,CNR1,COL9A1,AKAP5,GAL3ST1,IGDCC3,RIMS4,PHACTR3,CNTNAP2,SNAP91,DUSP9,EDN3,ADGRV1,NRN1,TMEM132C,HPCAL4,FOXF2,CSPG5,SRRM4,CPLX2,GFRA2,FREM1,RUNDC3A,CCDC184,STMN2,GRIA2,C1QL4,GRM8,GUCY1A1,UBE2QL1,IGFBPL1,CELF5,C2orf72,IGF1,NKD1,INSM1,MAP6,MAPT,LRP1B,TAGLN3,MYT1,FXYD7,NEFM,NTRK2,NTRK3,PCDH8,SEMA5B,PDZRN4,MAGEL2,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,HUNK,KCNIP1,RTN1,TMEM200C,DMRTC1,SNAP25,CABCOCO1,FAIM2,CLSTN2,SST,SYT5,ASXL3,RASD2,ZIC1,CRB2,DPYSL5,FAM181A,PRRT4" Coexpression Atlas gudmap_developingGonad_P2_ovary_500 DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.08E-06 1.98E-02 2.68E-05 2.43E-04 68 380 "TMCC3,LCORL,PKP4,LGR5,PLA2G4C,BACH1,ST3GAL5,ABI3BP,MYRIP,RBM39,GDA,CSNK1E,PLXNA4,GSDME,SNAP91,SLC12A6,PLXNC1,EIF4G1,EPB41L2,LRRC17,SCML2,GATM,GDF9,MAP7D2,LPAR4,SHISA6,KIT,SYTL4,CHIC1,MMP16,MYO5A,NEXMIF,SETD4,PDPK1,ABCB1,MAPK10,GDPD1,STK32A,SUSD4,TMLHE,MEG3,FNIP1,ARX,KIF16B,CPEB3,SYBU,SLC12A2,SLC14A1,CPEB4,ZC3H13,RBM26,CLSTN2,SYNE2,ANKRD12,CAMTA1,DMXL2,MTMR14,CBX5,PARD3,SSBP2,UCHL1,TBC1D15,TRIM9,NDRG4,ADAMTS9,FAM47E,DPF3,GAN" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000 DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.19E-06 2.03E-02 2.75E-05 2.49E-04 125 819 "ABCF1,NCKAP5,ADD1,AP2A2,AGT,TBC1D14,KIAA1324,SORCS2,AK2,TAOK1,C1QTNF3,ARHGAP20,LTBP4,AMH,OGT,SEMA7A,ARHGDIG,ARRB2,BACH1,ST3GAL5,PRMT9,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,SCARB1,COL9A3,RBM39,RNF14,SNCAIP,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,PLPPR4,SACS,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,ENPP6,NRN1,PTK2B,SCML2,FGFR1,BAIAP2,FYN,GATM,AHDC1,MAP7D2,LPAR4,GPR37,GRB10,SPACA9,GUCY1B1,IL6ST,KCNK3,KIF2A,TTYH2,MAPT,CHIC1,MEF2C,MYO7A,NEXMIF,NEFH,NFIX,NNAT,SERPINI1,SEMA5B,PLEC,FXYD1,PCDH18,EXOSC10,FSD1,PRKACB,MAPK3,BCAS3,PTPRE,MRPS18A,MEG3,SEC14L1,ARX,SMARCA4,SNRPN,SPP1,RBM26,SPART,TROVE2,SULF2,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,OBSL1,PUM2,TMPO,TNS1,TPM1,NR2C2,TST,UBTF,UCHL1,USP1,ZNF142,ZFAND5,INTS3,STOX2,ADAMTS9,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000 kidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.41E-06 2.14E-02 2.89E-05 2.62E-04 120 780 "ACADM,NDRG2,OSBPL6,ADGRF5,SPARCL1,C6orf89,DDO,ASPA,ATP1A1,SLC4A4,ALDH7A1,MYOM1,SEC11C,CFLAR,LDHD,CA4,CA12,CACNA2D1,CALB1,CLDN10,DCLK1,CDO1,NDST3,TPP1,CLTB,ABCG2,ARHGEF6,RGS6,CTH,ARHGAP24,DGKB,DBI,FAM107B,DMD,EBF1,EDIL3,EDN1,EDNRA,EDNRB,HEYL,FRY,FAM13A,AASS,CALCRL,RCAN2,ENPP6,ERBB4,ETV1,PIPOX,DLC1,FGF1,FHL1,FOLH1,FUT9,GATM,ALDH1L1,TUBA8,GHR,PPARGC1A,GNAO1,GSTT2,GUCY1A1,GUCY1B1,HLF,TCEAL6,HSPA1L,SCIN,SLC6A17,KCNJ16,KHK,AQP11,MEF2C,MYO6,NFE2L2,NFIX,IGSF11,PCDH9,PDE3A,PDE4D,ENPP2,PGAM2,ABCB1,SERPINI1,PLCL1,FXYD1,PLTP,SEPT4,MINDY2,PPP1R1A,PRODH,RELN,PTH1R,PTPRB,ACSM5,FIGN,SUGCT,LRRK2,STUM,SLC4A3,SLC2A5,SLC8A1,SLC12A2,CPEB4,LIMCH1,LMBRD1,SPP1,TEX2,NXT2,ADHFE1,PLCB1,SLC19A3,TLR4,TNS1,TPM2,PPIL6,CA14,UGT8,VLDLR,KCNAB1,RGS7BP" Coexpression Atlas GSM538198_500 "B cells, B.Fo.PC, IgD+ IgM+ CD19+ CD43- CD5- CD23+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 4.52E-06 2.20E-02 2.96E-05 2.68E-04 64 352 "ZNF608,TXNDC16,CARNS1,FGD2,INSYN2B,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD38,CDC25B,LY86,CNN3,CSNK1G3,KIAA0040,RUBCN,CYBB,HDAC9,MYADM,RIPOR2,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,HVCN1,B4GALNT1,ACSS1,MALT1,RAB30,DCLK2,TPPP,ADAMTS6,IRAK3,BACH2,IL12A,MEF2C,MYO5A,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,LRRK2,MAPK12,RASA3,ST6GAL1,LMBRD1,ARHGAP26,STAC2,SLC37A2,MGRN1,TCF4,CYB561A3,C9orf85,TRIO,LAT2,SIGLEC10,MPPE1,PLD4,PHTF2" Coexpression Atlas GSM605836_500 "Myeloid Cells, DC.8-4-11b-.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.55E-06 2.21E-02 2.97E-05 2.70E-04 73 418 "ACTN1,FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,LARGE1,UBE2L6,ARHGAP22,STOML1,LY86,SLC4A8,CDC42BPB,OSBPL3,CST3,CYBB,MYADM,RASSF2,PLPPR4,ARRDC4,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,FDFT1,ZMYND15,MTHFD2,RAB30,ADAP1,SLC2A6,HMGCR,HSF2,IRF8,SCIN,INSM1,JAK2,NCOA7,ASPRV1,MYO9A,PFKFB3,CCSER2,PLCL1,EML5,ROGDI,ZDHHC14,RGS12,LRRK2,RTN1,SEMA6D,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,SULF2,TMEM150C,ARC,ATMIN,CYB561A3,SIRT1,SLC44A1,SYNPO2,TUBB2A,CLIP2,ZBTB38,SPIRE1,ITM2C" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 5.05E-06 2.45E-02 3.30E-05 2.99E-04 77 449 "ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,IL33,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,TIAM2,DRP2,SNX29,TMTC1,RASA4,RAB9B,PTK2B,HPCAL4,STAMBP,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,KNDC1,SCIN,KLHL23,GPR155,MID1,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,PILRA,PRKAR1B,MASP1,STRC,ACSS3,ZCWPW1,ZNF493,ZMAT4,DUSP15,PRIMA1,STK32B,LRRK2,LRFN5,MRAS,ASAP3,ARHGAP26,IQSEC2,ADGRL3,FAM189A1,SLC44A1,LAMP5,CADM2,DNAH10,DPF3,PRRT4" Coexpression Atlas GSM538271_500 "Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3" "Immgen.org, GSE15907" 5.15E-06 2.50E-02 3.35E-05 3.04E-04 72 412 "FMNL2,ADCY6,TMCC3,ADORA2A,CC2D2A,CEP126,SEMA7A,TMEFF1,ZBTB10,N4BP2L1,ADAM23,NRP2,CFLAR,CDH2,LARGE1,UBE2L6,ARHGAP22,FAM189A2,LY86,ANKRD35,SLC4A8,ABCG1,CST3,PNPLA8,RASSF2,PLPPR4,MAMLD1,DNM1L,PLXNC1,RASA4,ENO2,EPB41L2,MTSS1L,DENND4A,MEX3B,ZMYND15,NBEA,MTHFD2,RAB30,SLC2A6,HSF2,SCIN,INSM1,JAK2,KTN1,TTYH2,ASPRV1,ADAM11,NPR2,PFKFB3,CCSER2,PLCL1,ROGDI,RGS12,DGLUCY,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,ST5,SULF2,STXBP1,ARHGEF9,TMEM150C,ARC,PHF24,SYNPO2,TRIO,TRPS1,ZBTB38,SPIRE1" Coexpression Atlas ratio_SC_vs_MESO_500_K5 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 5.16E-06 2.50E-02 3.36E-05 3.04E-04 56 296 "VAT1L,CLDN10,DCLK1,PCYT1B,LRRC3B,RIMS4,FAM131B,SEC14L5,HDAC9,JAKMIP2,PARD6A,CHRDL1,HS3ST2,AASS,ETV1,PIPOX,PPP1R1B,OLFM1,FLT1,NSG1,TOX3,GNAO1,GNG4,LPAR4,LINGO1,KCND2,KCNN2,KHK,KIF5A,CAMK2N2,FXYD7,NELL2,NOVA2,NPTX2,NTRK3,PCSK1,GDPD2,TMEM145,RORB,PPM1E,NLGN1,NMNAT2,SPP1,RHBDL3,ARHGEF9,ARC,SYP,SYT1,SLC19A3,PCDHAC2,ENHO,ANKRD24,VGF,VSNL1,LAMP5,TMEM63C" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_500 DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.21E-06 2.53E-02 3.39E-05 3.07E-04 69 390 "RALGAPA1,OSBPL6,TAOK1,OGT,APC,EPB41L5,PDE8B,SLC4A4,GPR146,BMPR1B,CALB1,RGN,LRBA,CFL2,B4GALT6,CLCN3,FAM149A,COL4A5,SLC35F1,OSBPL3,IPCEF1,CTH,MFAP3L,PLPPR4,SEMA3D,TENM1,EMX2,MED12L,SUCO,SYNCRIP,PDLIM5,CAMKK2,GALC,RAPGEF6,SYT17,IGSF5,PPARGC1A,PADI2,SCIN,SLC35G1,KCNJ16,KIF2A,L1CAM,AQP11,CHIC1,KITLG,VWA2,PIK3C2A,KANSL1,MAPK4,RASGRF2,RET,REV3L,SCN8A,TRA2B,HKDC1,SLC8A1,FAM126B,MYCBP2,ATP10B,VPS13A,ERCC6L2,RGMB,SSBP2,RPRM,UGT8,VLDLR,EMX2OS,LYPD6" Coexpression Atlas GSM538230_500 "B cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5+ CD45R+, Peritoneal Cavity, avg-1" "Immgen.org, GSE15907" 5.32E-06 2.58E-02 3.45E-05 3.13E-04 61 332 "ADORA2A,TXNDC16,SEMA7A,FGD2,GAS7,TMEFF1,NRP2,BTK,CACNA1I,CD86,CD38,LY86,CNN3,CDC42BPB,SIPA1L1,RUBCN,CYBB,MYADM,GUCD1,EBF1,RASGRP1,FRY,PLXNC1,KCTD3,SRPK3,DENND4A,TLR7,AK8,TPPP3,ACSS1,MALT1,RAB30,TPPP,ADAMTS6,MAP4K5,IRAK3,ITGAM,LIFR,MEF2C,MYO5A,NUCB2,PPP3CC,DIRAS2,MARCH1,BEND5,LRRK2,RASA3,ST6GAL1,LMBRD1,STAC2,SLC37A2,TCF4,CYB561A3,TLR4,C9orf85,TUBB2A,LAT2,EVI5,SIGLEC10,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K1 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 5.47E-06 2.66E-02 3.54E-05 3.21E-04 75 435 "METAP1D,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,ZNF599,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,TIAM2,DRP2,SNX29,TMTC1,RASA4,PTK2B,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,GNG4,ADAP1,GUCY1B1,TCEAL6,KNDC1,SCIN,KLHL23,GPR155,MID1,MITF,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,STRC,ZCWPW1,ZNF493,ZMAT4,DUSP15,MORC4,PRIMA1,STK32B,LRFN5,MRAS,SGK1,ASAP3,IQSEC2,ADGRL3,FAM189A1,LRRC24,KCNE5,LAMP5,CADM2,DNAH10,DPF3,PRRT4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.56E-06 2.70E-02 3.60E-05 3.26E-04 11 23 "VAT1L,CHGB,SYT17,GFRA2,STMN2,L1CAM,NELL2,SLC10A4,RGS4,SYT1,UCHL1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.61E-06 2.72E-02 3.62E-05 3.29E-04 21 71 "SYT13,KIF1A,SEPT7,CDC25B,CRMP1,KIAA0408,SEZ6L2,PRMT5,NSG1,GNAO1,STMN2,BEX5,RTN1,SNAP25,MAPKBP1,PEG10,SS18,MTMR14,VGF,CELF4,REEP1" Coexpression Atlas GSM605878_500 "Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2" "Immgen.org, GSE15907" 5.62E-06 2.73E-02 3.63E-05 3.29E-04 72 413 "RNF150,MTUS1,ALCAM,FGD2,APOC2,CASK,ATP1A3,ADAM15,ST3GAL5,DDR1,SCARB1,UBE2L6,LY86,ZNF385A,CDC42BPB,GDA,CSF1R,CSF2RA,GALNT9,CST3,CYBB,DOCK4,MYADM,DGKG,DAPK1,ARRDC4,EBI3,RASA4,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,FGFR1,TPPP3,GCNT2,ADAP1,SLC2A6,PADI2,HP,IFI16,LRRC25,IL6R,ITGAM,L1CAM,LIFR,RTL5,NCF2,PFKFB4,PLTP,PILRA,PTPRO,PID1,C1orf54,LRRK2,RTN1,SH3BP2,SLC8A1,SLC11A1,SLC12A2,ELMO2,SULF2,KIAA0930,TIAM1,TRIO,LAT2,AMZ1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k5 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.63E-06 2.73E-02 3.63E-05 3.29E-04 40 187 "EMILIN3,ADRB2,MYOM1,CNTN1,COL9A1,VCAN,PLCXD3,RGS17,DCTN4,NCALD,ETV1,RASL12,PDLIM5,MEGF10,GFRA2,FERMT2,PRUNE2,RBPJ,LIMS1,HECTD2,MBNL1,NPTX2,NTRK2,CNTN3,PCDH9,NALCN,DIRAS2,LGI2,KCNIP3,SH3BGR,SH3GL3,SYT1,SYNE1,RASD2,TPM2,SYNPO2,TRPS1,SSBP2,RBFOX3,MSRB3" Coexpression Atlas Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(2) Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(2) Lungmap CCHMC 5.67E-06 2.75E-02 3.65E-05 3.31E-04 57 304 "ABCF1,SYN3,NCKAP5,SPARCL1,SEMA6A,SEMA7A,PRX,DYNLL1,GPR146,SGCE,CA4,LDB2,SCARB1,CNN3,PPP1R16B,GIT2,PITPNC1,EDIL3,EDN1,EDNRB,PLEKHA1,CALCRL,TUBA1B,FLT1,NSG1,PCDH17,LYVE1,FERMT2,STMN2,MUM1,GABARAPL2,NKD1,MAPT,MEST,KITLG,PCBP3,OPA1,PCSK5,PDE4B,PMP22,SEPT4,PTPRB,PTPRG,C1orf54,RDX,RGS12,RTN1,SCN7A,SGK1,UNC5B,THSD1,PLCB1,PDLIM2,TCF4,TEK,TUBB2A,TUBA1A" Coexpression Atlas gudmap_developingGonad_P2_testes_1000_k4 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.09E-06 2.96E-02 3.92E-05 3.55E-04 59 319 "EMILIN3,TMCC3,ADORA1,MTUS1,SORCS2,C1QTNF3,AMH,SEMA7A,NT5C3B,ARHGDIG,MARK4,DST,ST3GAL5,VXN,CBLN1,CLTB,CABP1,RASGEF1C,ARHGEF4,SPOCK2,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,RASL12,REEP2,FGF13,CAMKK2,TPPP3,FYN,GATM,GPR37,IL6ST,ITPKA,TTYH2,MEF2C,MOV10,NRBP2,MYO7A,SEMA5B,PLEC,FXYD1,ELOVL2,PTPRE,MEG3,S100B,SPP1,SULF2,TBL1X,SIN3B,THRA,NR2C2,TST,SGK3,UBTF" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 6.19E-06 3.01E-02 3.98E-05 3.60E-04 20 66 "APLP1,THSD7A,KALRN,EBF1,SEZ6L2,NRN1,MEX3B,DLL3,STMN2,IGFBPL1,INSM1,MAP6,MEIS2,TAGLN3,NEFM,PRPH,RTN1,NFASC,ZEB1,ZIC1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 6.33E-06 3.07E-02 4.05E-05 3.67E-04 22 77 "XKR4,TMCC3,SYT13,CALB1,RUNX1T1,CHGB,TENM1,TMEM35A,NSG1,GNAO1,GNG4,STMN2,NEGR1,LSAMP,HS6ST3,RTN1,PEG10,LMO3,SEPT3,VGF,CELF4,CADM2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglb_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglb_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 6.33E-06 3.07E-02 4.05E-05 3.67E-04 62 341 "AXIN2,RNF150,SORCS2,C1QTNF3,C6orf89,RASL11B,CDC25B,CDH2,CDO1,CDR1,CHN2,COL4A5,ZNF521,CNRIP1,LRRC3B,CNTNAP2,DCAF8,SEZ6L2,ADGRV1,ABCA8,TMEM132C,TMEM107,ERGIC3,GRM8,GSN,IGF1,KCND2,LAMA2,LAMP2,MBNL1,LRP1B,KCTD6,MID1,NFE2L2,NUCB2,CNTN3,PAX6,PDE3A,PDE4B,PKM,KCTD15,PLTP,PURG,FAT4,RFX3,MRPS18A,KIRREL1,GALNT10,PUF60,ARX,SLC8A1,MIR100HG,SYNE2,TCF12,TPM1,ZIC1,ZIC2,FSTL5,MFF,DNALI1,FAM13C,NHSL1" Coexpression Atlas geo_heart_2500_K5 geo_heart_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 6.76E-06 3.28E-02 4.32E-05 3.92E-04 95 590 "DPY19L2P4,HFM1,CARNS1,TRMT9B,PI16,MYH7B,PPFIA4,DDO,CPNE5,SPTBN4,PDE8B,TMEM108,SLC4A4,SLC2A11,RGS11,HCN2,CAMK2B,VXN,USP2,RGN,P2RX6,LONRF2,CFL2,CHGB,FAM189A2,COL9A1,TOGARAM2,CRYM,DTNA,EGR3,ELN,C3orf18,RAB9B,RASL12,F5,FGF1,FGF12,FHL1,TPPP3,HRASLS5,CPLX1,IGSF5,TUBA8,CYP46A1,AHDC1,GFRA2,GHR,PPARGC1A,NTNG2,GNAO1,TMEM121B,TPPP,PLPP7,SPACA9,GRIN2C,BVES,UBE2QL1,NXPH3,FRMD3,SYNPO,C9orf129,HP,FAM95B1,LRRC25,KIAA1755,CDH20,KCNK3,ADAM11,COL28A1,NTRK2,CDK18,PGAM2,VSTM2L,SMIM10L2B,CRTAC1,SGSM1,S100B,SCN2B,CPEB3,PKNOX2,SMARCD3,NMNAT2,NFASC,CLSTN2,KANK1,SYN1,SYNE1,TPM2,VLDLR,REEP1,SEMA3B,GAL3ST3,WNK2,EPM2A,ADAMTSL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 7.12E-06 3.46E-02 4.55E-05 4.12E-04 18 56 "APLP1,CALB1,THSD7A,RUNX1T1,EBF1,SEZ6L2,NRN1,NSG1,STMN2,IGFBPL1,L1CAM,MAP6,TAGLN3,NEFM,PKIA,RTN1,ZIC1,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.15E-06 3.47E-02 4.56E-05 4.14E-04 21 72 "TMEM132B,TMCC3,PCDH10,SYT13,CALB1,CHGB,TMEM35A,NSG1,FUT9,TOX3,GNAO1,STMN2,NEGR1,LSAMP,RET,RTN1,PEG10,SSTR2,SEPT3,VGF,CELF4" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K4 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 7.27E-06 3.53E-02 4.63E-05 4.20E-04 52 271 "AS3MT,NDRG2,GALNT16,RNF150,MTUS1,CASKIN1,CARNS1,BEGAIN,TRMT9B,MYH7B,TNRC6C,CPNE5,SPTBN4,ZSCAN18,SLC2A11,AZGP1,SLC25A18,TMEM132C,CHL1,BACH2,HP,DUSP26,TMEM38A,SLC25A23,ROGDI,CRTAC1,DCUN1D2,DGLUCY,SMPD3,KIF21A,ASAP3,FHOD3,PKNOX2,GKAP1,ABTB1,TSPYL2,LHPP,CLSTN2,HIF3A,ZNF106,CDH22,PDIA2,PCDH20,NDRG4,REEP1,ADAMTS9,SLC17A7,PCBP4,WNK2,HRASLS,ADAMTSL3,ADAMTS10" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_500 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.56E-06 3.67E-02 4.81E-05 4.36E-04 71 409 "HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,SHROOM2,NRP2,ARHGEF7,CA8,LDB2,CD38,ABCG2,LY86,ARHGEF6,ZNF521,CRMP1,HAPLN1,CSF1R,CYBB,PITPNC1,ELMO1,FAM107B,EBF1,EDN1,EDNRB,PLEKHA1,CALCRL,RASGRP2,FLT1,PDLIM5,FYB1,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,LPAR4,MAP4K5,NCKAP1L,ZDHHC15,ICA1,IGF1,KIT,LMO2,TM6SF1,MEF2C,MEST,MSR1,PDE4B,RASGEF1B,SNRK,PTPRB,TMEM255A,C1orf54,SEMA6D,RASA3,SGK1,PREX2,BTBD3,LIMCH1,PEG10,SAMSN1,THSD1,KLHL4,TEK,ZFPM2,FLRT2,WIPF1,ZNF711,ADAMTS9,NAV3" Coexpression Atlas PCBC_DE_1000 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000 PCBC 7.56E-06 3.67E-02 4.81E-05 4.36E-04 145 991 "KCNH8,TMEM132B,GALNT13,PTCHD1,ZNF578,SEMA6A,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,APOC1,LGR5,PPP4R4,ARSE,RASL11B,KIF1A,BTK,CACNA1I,CACNA1G,BAIAP3,CALB1,CLDN10,USP2,DCLK1,L3MBTL4,PLEKHB1,LHX2,FAM189A2,IGLON5,PCYT1B,COL9A1,GAL3ST1,IGDCC3,IPCEF1,RIMS4,CNTNAP2,PLXNA4,FAM169A,PPP1R16B,PLCXD3,KIF26A,LONRF1,BRINP1,CHRDL1,SLC25A18,FAM78B,SEMA3D,PIPOX,ADGRV1,PPP1R1B,CSPG5,MEGF10,HRASLS5,CHL1,GABRB3,GAD1,GATM,FREM1,GNAL,TMEM121B,HAS2,IGFBPL1,C9orf129,USP51,SHISA6,CELF5,NKD1,C2CD4C,CDH20,KCND2,KCNF1,KIT,CAMK2N2,MATK,MATN3,MYT1,NNAT,SLC10A4,SEMA5B,JAKMIP1,PDZRN4,MAGEL2,FA2H,PPP2R2B,PPP2R2C,RASGEF1B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,NKAIN1,TMEM255A,SLC25A48,ACSS3,FAM184A,KHDRBS2,RET,PRIMA1,MRAP2,HUNK,SALL1,TMEM200C,SH3GL3,INAVA,CABCOCO1,SOX3,MCF2L2,NUDT10,ADAMTS17,TMEM150C,COBL,TBCEL,KLHL4,FAM189A1,ARHGAP9,PCDHA6,PCDHA3,PCDHA2,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,IL34,TRPM2,CA14,TUBB2A,RPRM,VIPR2,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,MEIS3,CADM2,STOX2,GAL3ST3,WNK3,PLSCR4,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.61E-06 3.69E-02 4.83E-05 4.38E-04 30 125 "CDC14B,AP4M1,BOC,CDON,TSPAN5,NRN1,AFF2,TRAF3IP2,RAB30,KLHL23,MATN2,MEIS1,NEXMIF,NNAT,PCDH18,MAPK9,TUG1,REV3L,RNASEL,MEG3,PEG10,ST5,SYNE2,ADAMTS17,ADGRL3,OBSL1,ZFPM2,TRPS1,PLEKHH2,DPF3" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 Gudmap RNAseq 7.68E-06 3.73E-02 4.87E-05 4.42E-04 25 95 "KIAA1324,EPB41L5,KIF1A,CAMK2A,ARHGAP22,NRXN3,IQCK,IGDCC3,ADGRV1,FUT9,RNF165,TOX2,FRMD5,MAP6,MSI1,NRCAM,PLTP,MAPK4,GDPD2,ELOVL2,NKAIN1,RTN1,HSPA4L,ANKFN1,DPYSL5" Coexpression Atlas ratio_SC_vs_MESO_1000_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 7.90E-06 3.84E-02 5.00E-05 4.53E-04 33 144 "ATP1A3,AZGP1,LDHD,CHGB,CABP1,NCALD,HSPA12B,ABLIM2,CPLX2,ALDH1L1,LNX1,CCDC184,FRMD3,INSYN1,NEGR1,MAPT,MT1M,PDE3A,FXYD1,SCHIP1,SEPT4,NKAIN4,PTPRO,FHOD3,TIMP4,RASD2,SYNPO2,LGI4,TRIM9,CRB2,SLC30A3,SLC17A7,KCNAB1" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 7.97E-06 3.87E-02 5.04E-05 4.57E-04 74 432 "FAM135A,PKP4,APC,CDC14B,NUMB,BBS2,SEC11C,PTBP2,LRBA,ARHGEF2,SRSF11,PCYT1B,IGDCC3,CLIP3,SNCAIP,GSDME,DDX46,FAM107B,DNM1L,EDIL3,KLHL5,MTSS1L,CEP85L,ETV1,NSRP1,TMEM132C,AFF2,SYT3,SMC2,STAU2,HIGD1B,ZNF276,CIT,HLF,IGF1,KCNJ5,LIMS1,MAN2A2,SAMD5,NFE2L2,NPY,PDE4D,PRIMPOL,DIRAS2,CNTLN,NWD1,REV3L,ZFHX4,PLPPR3,CLIP1,DGLUCY,PREX2,DHX30,SEPHS1,TET1,SMARCC2,CDK5RAP2,SPATA7,BDP1,SOX11,ARHGAP26,RBM26,TCEA1,SATB2,SYNE1,PHF24,SIRT1,AMACR,TRO,STXBP4,TRPS1,ZKSCAN5,ZNF711,HNRNPA3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.68E-06 4.21E-02 5.48E-05 4.97E-04 45 224 "FMNL2,KLHL13,PPP4R4,WASF1,CALB1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,TMEM35A,EMX2,NRN1,ABCA8,IP6K2,TCEAL6,KCND2,KLHL23,KITLG,MYO9A,SERPINI1,PPP3CC,CNTLN,FAT4,ZFHX4,HUNK,RASA3,SLC4A3,ATF7IP,SNCA,KDM3A,UHRF1BP1L,ST5,ADGRL3,TCF12,SZT2,DNAH7,ACTR6,KAT6B,PCDH20,LYPD6,DPF3" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000_k5 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.70E-06 4.22E-02 5.49E-05 4.97E-04 34 151 "PKP4,BACH1,SGCE,SRSF11,RBM39,ZC3H11A,EDNRA,EIF4G1,CALCRL,EMX2,EPB41L2,SRRM1,SMC2,APOPT1,LPAR4,CHIC1,MMP16,CNOT4,NALCN,PIK3R1,PLEC,TMLHE,SLC12A2,ZC3H13,PRRC2C,SYNE2,PCDHB9,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,ADAMTS9,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 8.82E-06 4.28E-02 5.54E-05 5.02E-04 14 37 "NRP2,SEPT7,CRMP1,TUBB3,NSG1,STMN2,TAGLN3,NEFM,PCDH9,LRRN3,MEG3,RTN1,SEPT3,UCHL1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.82E-06 4.28E-02 5.54E-05 5.02E-04 14 37 "NRP2,SEPT7,CRMP1,TUBB3,NSG1,STMN2,TAGLN3,NEFM,PCDH9,LRRN3,MEG3,RTN1,SEPT3,UCHL1" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 8.82E-06 4.28E-02 5.54E-05 5.02E-04 36 164 "OSBPL6,PCDH10,CADPS,CACNA2D1,CALB1,NRXN3,LY86,CNTN1,CNRIP1,CRYM,VCAN,EPB41L2,NCALD,MRVI1,GALC,GUCY1A1,NEGR1,MMP16,CLDN11,PCDH8,PIK3C2A,KANSL1,NKAIN4,PTPRO,PTX3,REV3L,LRFN5,SCN7A,CXXC4,STX1A,PDLIM2,ERCC6L2,SYNPO2,SSBP2,PROCA1,NAV3" Coexpression Atlas GSM605872_500 "Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 8.98E-06 4.36E-02 5.63E-05 5.10E-04 71 411 "AP2A2,MTUS1,ALCAM,ABCD2,AMPD3,GAS7,APOC2,CASK,ATP1A3,ADAM15,BACH1,SCARB1,SOCS6,B4GALT6,LY86,GDA,CSF1R,VCAN,CYBB,DOCK4,MYADM,ARHGAP24,DGKG,FBXL5,ARRDC4,IGSF6,TLR7,SIRPB1,F5,FCGR1A,FCGR3A,OLFM1,CAMKK2,TPPP3,GCNT2,ADAP1,IRAK3,HP,IFI16,LRRC25,IL6R,ITGAM,LAMP2,LIFR,TM6SF1,MSR1,MX1,NCF2,P2RY1,PILRA,DRAM2,VPS13C,MTMR10,PID1,C1orf54,ATP8B4,LRRK2,SH3BP2,SLC8A1,CCDC88A,SLC11A1,ARHGAP26,SULF2,PLCB1,DMXL2,TIAM1,TLR4,TRPS1,EVI5,PLD4,NLRP3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 9.09E-06 4.41E-02 5.70E-05 5.16E-04 10 20 "CNTFR,CLIP3,NSG1,GFRA2,ACOT7,TAGLN3,NNAT,PRPH,SST,UCHL1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.28E-06 4.50E-02 5.81E-05 5.26E-04 29 120 "PCDH10,THSD7A,RUNX1T1,CDH2,DCLK1,CLGN,SLC35F1,SIPA1L1,ERC2,GPSM1,EDNRA,ETV1,EYA1,TMEM132C,FOXF2,MEGF10,AGBL5,IFI16,MARK1,GPR85,PTPRG,FAT4,ZFHX4,ANKRD6,SOX11,ASXL3,KAT6B,RPRM,ST8SIA2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_250 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_250 FaceBase_ST1 9.37E-06 4.55E-02 5.86E-05 5.31E-04 43 211 "MTUS1,TMEFF1,PRC1,NOG,LHX2,CRMP1,SCRN1,JAKMIP2,GSDME,EPHB1,KATNAL1,GORAB,SLC37A3,STAU2,C15orf41,RUNDC3A,TDRKH,STMN2,GSTT2,SOX21,FRMD5,NIM1K,PACRG,CHIC1,TAGLN3,NELL2,SLC10A4,GPSM2,MINDY2,PPP2R5E,NKAIN4,MAPK10,GDPD1,ADAL,MRAS,HSPA4L,SH3GL3,SPART,CUX2,TCF12,XRCC4,ZIC1,ATP6V0E2" Coexpression Atlas GSM605811_500 "gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3" "Immgen.org, GSE15907" 1.02E-05 4.93E-02 6.34E-05 5.75E-04 70 405 "ABR,MTA3,APLP1,BAIAP3,HIP1R,CD38,NUMBL,CHN2,OSBPL3,IPCEF1,SIPA1L1,PPP1R16B,PITPNC1,ARRDC4,HEYL,RASGRP1,EPB41,DENND4A,EZH1,PTK2B,FDFT1,FOXO3,HVCN1,FYN,IGSF5,GCNT2,HPGDS,GPD2,GPR34,PADI2,FRMD5,ACOT7,HMGCR,CFAP126,AGFG1,SCIN,ITPKB,KIT,STXBP5,HECTD2,MYO6,NEFH,NRCAM,P2RX7,ZNF827,ABCB1,PIK3R1,PLTP,SEPT4,PPP2R2C,PPP3CC,PRKACB,SUSD4,ZMAT4,MRAS,FAM102A,ELMO2,PDZD2,SP4,SPP1,TEX2,SULF2,FRYL,C18orf54,PRRT1,TRIO,RUNDC3B,VIPR2,LAT2,ZBTB38" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_200 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.02E-05 4.94E-02 6.34E-05 5.75E-04 36 165 "FMNL2,LGR5,PPP4R4,PDE8B,INSYN2B,CALB1,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,MRO,EMX2,NRN1,NSG1,GATM,KCND2,KLHL23,KITLG,LAYN,NPR2,ENPP2,PCDH18,GDPD2,PRCD,TNFRSF19,STUM,SLC4A3,KDM3A,ST5,ADAMTS17,ADGRL3,ACTR6,LYPD6,WNK3,FRMD6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.02E-05 4.96E-02 6.36E-05 5.76E-04 20 68 "TMCC3,AP2A2,PCDH10,ZBTB10,NRXN3,CRHBP,KIAA0408,NSG1,AP4B1,STMN2,NEGR1,LSAMP,TAGLN3,GPR173,PDZRN4,MEG3,RTN1,UCHL1,CELF4,REEP1" Coexpression Atlas GSM403988_500 "CD positive, CD19 Control, 19+ 4- 8-, Spleen, avg-6" "Immgen.org, GSE15907" 1.05E-05 5.07E-02 6.50E-05 5.89E-04 61 339 "ZNF608,TXNDC16,CARNS1,FGD2,INSYN2B,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD86,CD38,LY86,CNN3,RUBCN,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,PLXNC1,SRPK3,DENND4A,TLR7,HVCN1,MALT1,RAB30,DCLK2,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,KTN1,LMO2,PIK3AP1,GPR155,MEF2C,MYO5A,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,LRRK2,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,TCF4,CYB561A3,TLR4,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k1 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.08E-05 5.26E-02 6.73E-05 6.10E-04 44 219 "USP31,ADGRF5,ARRB1,LDLRAD4,CA8,LDB2,CD86,CD38,MS4A7,LY86,CSF1R,CYBB,ELMO1,EDNRB,EPHB1,IGSF6,TLR7,SIRPB1,F8,FCGR1A,FYB1,GGTA1P,LYVE1,NCKAP1L,IRF8,PIK3AP1,TM6SF1,MSR1,P2RY13,NCF2,P2RX7,PTPRB,SGK1,SLA,SLC11A1,ARHGAP26,SAMSN1,TAL1,ARHGAP9,TEK,TLR4,NPL,WIPF1,FAM13C" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.11E-05 5.39E-02 6.89E-05 6.24E-04 72 421 "EMILIN3,HECW2,C1QTNF1,TRMT9B,AMPD3,LRCH2,RNF182,NRP2,SGCE,LDLRAD4,RUNX1T1,CDH2,MAGI1,RCBTB2,SLIT2,AKAP5,FAM171B,CRHBP,HAPLN1,BRINP1,EDIL3,FRY,EPHB1,ETV1,MRVI1,TMEM132C,CORO2B,FOXF2,FLT1,SPECC1,MEGF10,GABRA3,CHL1,GABRB3,PCDH17,LYVE1,GPR37,STMN2,PARD3B,GRIN2C,RASSF8,HLF,NEGR1,IRF8,IFI16,KIT,MYO6,NDP,PDE4B,PCDH18,PMP22,MAGEL2,PRKCB,PTPRB,RGS4,ZFHX4,C12orf49,TRA2B,LIMCH1,CLASP2,NEK4,COBL,PCDHB7,ZFPM2,TMPO,TPM1,SYNPO2,TRO,RPRM,STOX2,ACTR3B,MSRB3" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_500 DevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.14E-05 5.51E-02 7.03E-05 6.37E-04 67 384 "USP31,HECW2,ADGRF5,ARRB2,NRP2,LDLRAD4,CA8,CD86,CD38,MAP4K4,LY86,RBM39,CRMP1,HAPLN1,CSF1R,PPP1R16B,CYBB,ELMO1,SEZ6L2,EDNRB,EPHB1,IGSF6,F8,CORO2B,FCGR1A,FLT1,TRIM16,FYB1,PCDH17,LYVE1,NCKAP1L,ICA1,IRF8,IGF1,LMO2,TM6SF1,MEF2C,KITLG,MSR1,MYO7A,NCF2,GNG2,KANSL1,SNRK,PTPRB,RIPOR1,TMEM255A,MAPK12,SGK1,ST8SIA1,SLA,PREX2,ARHGAP26,SAMSN1,THSD1,RGL1,TAL1,KLHL4,ARHGAP9,TEK,TLR4,NPL,TRIO,PLD4,RGS7BP,FAM13C,DOCK8" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_500 kidney_adult_Mesangium_Meis_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.16E-05 5.62E-02 7.16E-05 6.49E-04 73 429 "ACHE,ADCY6,APBB2,PDE8B,MYOM1,NRP2,CACNA2D1,ARHGEF6,CSF1,KIAA0040,HDAC9,DGKB,ZNF804A,NR1D2,ECM2,EBF1,EDNRA,FRY,CALCRL,RCAN2,LRRC17,RASGRP2,CEP85L,DLC1,ST3GAL6,CHST15,TVP23A,ERAP1,GUCY1A1,GUCY1B1,FRMD3,HLF,IFI16,IL6ST,INPP5B,LIFR,MEF2C,LAYN,NCF2,NFIX,PDE3A,ABCB1,SERPINI1,PIK3R1,PLCL1,FXYD1,PCDH18,SEPT4,MINDY2,PRKAB2,PKIA,SNRK,PTN,PTPRB,ZMAT4,RGS4,SGK1,PREX2,SLC8A1,SLC12A2,CPEB4,ITPRID2,RGL1,ANKRD12,ADGRL3,SYNE1,TNS2,GPRIN3,TEK,TLR4,TNS1,DOCK8,CPNE4" Coexpression Atlas GSM854290_500 "Myeloid Cells, DC.8-4-11b-.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-1" "Immgen.org, GSE15907" 1.18E-05 5.71E-02 7.27E-05 6.59E-04 66 377 "FMNL2,ADCY6,TMCC3,SEMA7A,FGD2,CASK,ZBTB10,N4BP2L1,ADAM23,NRP2,CDH2,UBE2L6,ARHGAP22,STOML1,LY86,ANKRD35,SLC4A8,CSF1,CST3,CYBB,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,ZMYND15,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,HSF2,IRF8,SCIN,INSM1,JAK2,KIT,LIFR,ASPRV1,ADAM11,NPR2,NUCB2,PFKFB3,CCSER2,PLCL1,ROGDI,ZDHHC14,RGS12,LRRK2,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,ARHGEF9,TMEM150C,ARC,PHF24,SLC44A1,SYNPO2,TUBB2A,SPIRE1,TUBA1A,SIGLEC10,PLD4" Coexpression Atlas Lungmap Mouse Lung PND1 Endothelial Subtype Vascular Endothelial-D Lungmap Mouse Lung PND1 Endothelial Subtype Vascular Endothelial-D Lungmap CCHMC 1.24E-05 6.02E-02 7.65E-05 6.93E-04 45 227 "SYN3,FMNL2,CCDC85A,ADRB2,SEMA7A,PRX,PDE8B,CA4,KALRN,ABCG1,KIAA0040,DPYSL2,FAM78B,EDN1,EDNRB,CEP85L,TPPP3,INPP5K,PCDH17,LYVE1,STARD3,GNAO1,GSTM5,FAM107A,TOX2,MAPT,KITLG,PMP22,KANSL1,SNRK,C1orf54,CLIP1,SEC14L1,BTBD3,SLC12A2,LMBRD1,PHLDB1,SLC35G2,PCDHA2,MTMR14,ASXL3,DCBLD1,RBFOX3,MKRN3,TUBA1A" Coexpression Atlas GSM777043_500 "Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3" "Immgen.org, GSE15907" 1.25E-05 6.06E-02 7.69E-05 6.97E-04 75 445 "FMNL2,PCDH19,ADGRF5,SPARCL1,SRPX,LTBP4,CDC42BPA,ANK2,APBB2,MPDZ,NRP2,SGCE,IL33,CACNA2D1,DCLK1,SLIT2,MAGED1,ABI3BP,AKAP12,CSF1,LRIG1,VCAN,DNM1,ECM2,EBF1,EDNRA,EGFR,CALCRL,ETV1,ABCA8,FAM198B,DLC1,FGFR1,FHL1,TPPP3,DENND2A,GFRA2,GHR,FERMT2,GRB10,GSN,HAS2,LAMA2,LIFR,MATN2,MEIS1,KITLG,NBL1,NPR2,P2RY1,ENPP2,PCDH18,PMP22,PTN,PTPRG,RET,ROBO1,KIRREL1,SCN7A,BTBD3,PDZRN3,ST5,SYNE2,TCF4,TNS2,TLR4,CSMD1,IL34,RGMB,SYNPO2,FLRT2,PLEKHH2,AGMO,ADAMTS9,ADAMTSL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.26E-05 6.14E-02 7.78E-05 7.05E-04 14 38 "THSD7A,EBF1,NRN1,TUBB3,STMN2,GRIA2,INSM1,MAP2,TAGLN3,NNAT,MEG3,RTN1,SEPT3,CELF4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.27E-05 6.15E-02 7.78E-05 7.06E-04 57 312 "RALGAPA1,EMILIN3,USP31,BEND6,FAM135A,OGT,APC,CASK,BMP7,CACNA2D1,CLIP3,SUSD5,VCAN,HDAC4,KIF26A,TM9SF4,ELMO1,GRIN3A,DNM1,EDNRA,EDNRB,HIPK3,SEMA3D,EPB41,SPEG,CELF1,GABRA3,IQGAP2,PCDH17,GHR,PPARGC1A,KIAA1958,PRRC2B,GRIA2,GUCY1A1,GUCY1B1,BACH2,MARK1,CHIC1,PPM1L,MKLN1,NCAM2,PDE3A,PIK3C2A,KANSL1,NKAIN4,REV3L,TNFRSF19,BTBD3,ZHX3,MYCBP2,CLASP2,RGL1,ERCC6L2,RGMB,TRIO,TRPS1" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500 FaceBase_RNAseq 1.29E-05 6.25E-02 7.91E-05 7.17E-04 81 491 "PLEKHH1,PTCHD1,FGD2,EPB41L5,BLM,PROM1,CA4,CACNA1B,HAP1,LRBA,SRSF11,CBARP,LHX2,NRXN3,CLCN3,IGDCC3,ABCG1,CRYM,OSBPL3,FAM169A,GREB1,CHRDL1,CDON,DTNA,DUSP9,EMX2,EPB41,RRAGB,ADGRV1,EYA1,ACSL4,TUBB3,KHDRBS3,FUT9,GAD1,SRRM4,KIAA1841,TOX3,PCLO,SOX21,PSIP1,FAM222A,TOX2,IGFBPL1,SHISAL1,KCNH2,KIT,KTN1,AQP11,MBP,MSI1,MYCN,NNAT,NRCAM,PAX6,PRTG,NECAB2,ELOVL2,PTPN13,EML5,SUSD4,GAL3ST4,FIGN,TRAPPC13,SALL1,MAPK12,KIF21A,FERMT1,SP4,NMNAT2,WSCD1,HEY1,NR2E1,CA14,ZIC2,DPYSL5,TFIP11,SLC38A1,PCBP4,FZD3,SPATA13" Coexpression Atlas Arv_SC-H9hpx_2500_K5 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 1.30E-05 6.30E-02 7.95E-05 7.21E-04 144 993 "KCNH8,SYN3,TMEM132B,ADCY8,GALNT13,SEMA6A,UNC79,PDZD4,DPP10,RASL11B,KIF1A,CARMIL3,RGS9,GYG2,HAP1,CLDN10,SYNGR3,DLGAP1,CACNA2D2,FAM189A2,FAM19A5,SULT4A1,IGLON5,COL9A1,COL9A3,GAL3ST1,IGDCC3,C1QL2,IPCEF1,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,LONRF1,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,CHRDL1,RAB39B,DPP6,SLC25A18,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SPSB4,MAD2L2,HPCAL4,SYT3,CSPG5,DLL3,TVP23A,MEGF10,HRASLS5,GABRB3,SYT17,SRRM4,TTBK1,TOX3,GNG4,GPT2,LPAR4,KAT7,SOX21,LINGO1,PSIP1,PADI2,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KIF5A,CAMK2N2,SCAMP5,ADAM22,FXYD7,NLGN3,SEMA5B,PNMA3,PSAT1,NECAB2,EPB41L4B,FA2H,PPP2R2B,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,FAM184A,ZMAT4,RET,LGI2,ZNF532,SALL1,TMEM200C,PPM1E,CNKSR2,SEPHS1,OGDHL,SNRPN,SOX3,NMNAT2,HECW1,SOX21-AS1,SEPT3,NECAB1,ARC,COBL,CUX2,FAM189A1,CCDC173,SIRT1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,KCNE5,CA14,TUBB2A,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,TMEM198,DPYSL5,DHX33,CADM2,STOX2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 1.30E-05 6.31E-02 7.96E-05 7.22E-04 20 69 "APLP1,THSD7A,IGDCC3,EBF1,SEZ6L2,EPB41,NRN1,DLL3,STMN2,IGFBPL1,INSM1,MAP6,TAGLN3,NEFM,PRTG,C1orf54,RTN1,TNFRSF19,SLC6A8,PCBP4" Coexpression Atlas GSM777021_500 "B cells, B.Fo.MLN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.38E-05 6.71E-02 8.45E-05 7.66E-04 61 342 "ZNF608,TXNDC16,CARNS1,BIN1,FGD2,SUGT1P4-STRA6LP-CCDC180,ATP6V0A1,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,CSNK1G3,KIAA0040,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,SRPK3,TLR7,HVCN1,RAB30,DCLK2,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,FAM69A,LMO2,PIK3AP1,MEF2C,MYO5A,NCF2,SERPINI1,PPP3CA,PPP3CC,RASGEF1B,CYBC1,MARCH1,C1orf54,BEND5,LRRK2,SH3BP2,ST6GAL1,LMBRD1,SYPL1,SLC37A2,CYB561A3,TLR4,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k3 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.38E-05 6.72E-02 8.46E-05 7.66E-04 25 98 "VAT1L,KALRN,NSL1,CRMP1,CRYM,SNCAIP,DUSP9,EYA1,GABRB3,BRD8,ADGRA3,FAM19A2,HAS2,NPTX1,CNTN3,PCDH8,PRTG,GAL3ST4,SALL1,ANKRD6,CLSTN2,ASXL3,STXBP4,ZNF184,INTS3" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_k4_500 kidney_e13.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.41E-05 6.82E-02 8.57E-05 7.77E-04 31 135 "VCAN,GSDME,AFF2,IGSF5,FREM1,HAS2,NEGR1,NEFM,NPY,NOVA1,OLA1,SPDL1,PTX3,TSPY26P,RMI1,CNKSR2,SLC4A3,GKAP1,CMTR2,ADAMTS17,CUX2,PCDHB9,PCDHB3,ITGB3BP,BHLHB9,STXBP4,TRPS1,ZNF708,STOX2,MRPL47,NETO2" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k2_500 kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.42E-05 6.88E-02 8.63E-05 7.82E-04 40 194 "ABR,RNF157,AMPH,VAT1L,SEMA4G,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,GSDME,SNAP91,DTNA,ETV1,EYA1,FGFR1,SCARA3,IGSF5,FREM1,TDRKH,FAM107A,HAS2,NEGR1,MEST,NME4,CNTN3,PRTG,SMOX,HUNK,SALL1,SLC4A3,NUDT10,ADAMTS17,CUX2,LAMP5,SIGLEC10" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_1000 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.45E-05 7.06E-02 8.84E-05 8.02E-04 33 148 "NCKAP5,LTBP4,APOC1,ATP1A3,CBLN1,SCARB1,DLGAP1,RAB33A,TCAF1,ARMCX2,EDNRA,HEYL,EGFR,DLC1,TMEM164,ALDH1L1,FREM1,GRB10,GUCY1A1,HMGCR,LSS,NPY,PCDH9,PLIN1,FXYD1,PLTP,LAMA1,STK32A,ROBO2,PPM1E,ARHGEF9,VSNL1,STOX2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_200_k5 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.46E-05 7.08E-02 8.84E-05 8.02E-04 19 64 "PKP4,BACH1,RUNX1T1,SLIT2,COL4A5,ZC3H11A,EIF4G1,EPB41L2,LPAR4,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,UBE3A,FLRT2" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500_K0 facebase_RNAseq_e8.5_FloorPlate_2500_K0 Gudmap RNAseq 1.46E-05 7.08E-02 8.84E-05 8.02E-04 19 64 "CAMK2A,IQCK,IGDCC3,ERBB4,ADGRV1,AFF2,HIGD1B,RNF165,TOX2,FRMD5,SHISAL1,MAP2,MAP6,NEFM,MAPK4,ELOVL2,HSPA4L,WSCD1,DPYSL5" Coexpression Atlas GSM605808_500 "gamma delta T cells, Tgd.vg5-.act.IEL, CD8a+ CD8b- TCRd+ Vg5- CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 1.48E-05 7.20E-02 8.99E-05 8.15E-04 69 402 "ABR,MTA3,APLP1,BAIAP3,LDLRAD4,CAPN3,HIP1R,CD38,RCBTB2,CHN2,LRIG1,OSBPL3,IPCEF1,PPP1R16B,PITPNC1,ARRDC4,HEYL,RASGRP1,EPB41,DENND4A,EZH1,ST3GAL6,FDFT1,FOXO3,HVCN1,FYN,RAPGEF6,IGSF5,GCNT2,HPGDS,GPR34,PADI2,ACOT7,HMGCR,ZDHHC15,CFAP126,AGFG1,SMAP1,SCIN,KIT,STXBP5,HECTD2,NEFH,P2RX7,ZNF827,ABCB1,PLTP,SEPT4,PPM1B,PPP2R2C,PPP3CC,PRKACB,SUSD4,EMID1,SEC14L1,FAM102A,ELMO2,TRERF1,SPP1,TEX2,SULF2,FRYL,C18orf54,PRRT1,TRIO,RUNDC3B,TTC3,VIPR2,LAT2" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k3 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.50E-05 7.26E-02 9.05E-05 8.21E-04 42 208 "TAOK1,APC,DDO,ADAM23,GPR146,CACNA2D1,PLEKHB1,AKAP6,CLOCK,OSBPL3,MFAP3L,CHRDL1,CPEB2,HIPK3,TMTC1,MBNL2,PCOLCE2,RCAN2,MRVI1,NRN1,GCNT2,GSN,HLF,KCNF1,MAP4,MBP,CCSER2,PLCL1,DIRAS2,RGS4,CLIP1,SCN7A,CPEB3,CPEB4,SYN2,NACC2,ERCC6L2,RGMB,ZBTB38,PLSCR4,FAM13C,DOCK8" Coexpression Atlas Lungmap Mouse Lung E16.5 Epithelial Subtype Proliferative AT1 Progenitor Lungmap Mouse Lung E16.5 Epithelial Subtype Proliferative AT1 Progenitor Lungmap CCHMC 1.51E-05 7.35E-02 9.15E-05 8.30E-04 76 455 "AS3MT,MTA3,SPARCL1,USP37,CHID1,MPDZ,PLEKHB1,CNN3,CNRIP1,NSL1,CLIP3,VCAN,GOLT1B,EDNRA,EDNRB,STARD3NL,RABEPK,ETV1,GMPR2,FGF1,PCYOX1,NOP56,NELFCD,WDR83,FREM1,GHR,RABL2A,GUCY1A1,ACOT7,IGF1,TTYH2,LAMA2,LYPLAL1,MEF2C,MEIS1,SCAMP5,NFE2L2,PDE4B,ZNF655,PLTP,PLXNB1,PMP22,PPP3CA,NKAIN4,PPP5C,MAPK3,APTX,PTH1R,PTPRD,C1orf54,FAT4,SLC25A36,ZFHX4,RNH1,ROBO2,CCDC25,ATAT1,SCN2B,FAM102A,CCDC88A,SMARCD3,INAVA,SNRPN,SOX11,KDM3A,SS18,DNAJC9,MGRN1,C18orf54,TRIO,VSNL1,PCDH20,TUBA1A,VPS35L,PLSCR4,IFT88" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.54E-05 7.48E-02 9.30E-05 8.43E-04 29 123 "OSBPL6,OSBPL8,ALDH7A1,DST,WASF1,CA8,CACNA2D1,FHL1,SYNCRIP,PDLIM5,GALC,RAPGEF6,ATE1,ZHX1,ZDHHC15,LIMS1,NCOA7,CHIC1,PDE1C,MINDY2,RYR3,FAM126B,ZHX3,ARHGEF9,VPS13A,COBL,ERCC6L2,TRPS1,VLDLR" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_500_k3 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.54E-05 7.49E-02 9.30E-05 8.43E-04 22 81 "C1QTNF3,SLC4A4,CHGB,COL9A1,IPCEF1,ELMO1,EBF1,DLC1,PDLIM5,GFRA2,RAB40B,RASSF8,IFI16,MATN2,MSR1,PIK3C2A,PTX3,ABLIM3,ZHX3,RGMB,PCDH20,MSRB3" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_500 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_500 FaceBase_ST1 1.54E-05 7.49E-02 9.30E-05 8.43E-04 68 395 "C3orf14,TAOK1,ZBTB10,RNF182,PTBP2,CDH2,LHX2,RAB33A,NECTIN3,KATNAL2,ZFYVE16,SCRN1,GSDME,C8orf37,EMX2,CDKL3,KATNAL1,NRN1,IQCG,EFCAB2,CSPG5,STAU2,TPPP3,C15orf41,GATM,SESN1,RAB30,TOX3,TDRKH,CACFD1,IGFBPL1,USP51,PACRG,LYPLAL1,CHIC1,TAGLN3,NELL2,NTRK2,PAX6,ETFRF1,SLC25A23,ZNF426,MINDY2,PPP2R5E,NKAIN4,PKIA,GDPD1,SLC25A36,NUDT11,PBRM1,ARMH4,CCDC112,SCP2,HSPA4L,KIF21A,SLC4A3,NUDT10,ADAMTS17,DMXL2,CCDC173,HEY1,NR2E1,NPL,TRPS1,XRCC4,ZIC1,AMN1,NETO2" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.55E-05 7.52E-02 9.31E-05 8.44E-04 36 168 "FMNL2,PPP4R4,NUMB,CALB1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,RASGRP1,TMEM35A,EMX2,NRN1,PACSIN2,KLHL23,KITLG,AFF1,MYO9A,NUCB2,SERPINI1,PIK3C2A,ZFHX4,HUNK,TNFRSF19,SLC4A3,SNCA,UHRF1BP1L,ST5,ADGRL3,DNAH7,ACTR6,PCDH20,ZNF23,DPF3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.55E-05 7.52E-02 9.31E-05 8.44E-04 36 168 "SPARCL1,ALCAM,ABCD2,ARHGAP20,LTBP4,CACNA1G,ARHGEF25,SLIT2,ABI3BP,SNCAIP,VCAN,ARMCX2,EDNRA,EGFR,LRRC17,DLC1,CHST15,ST6GALNAC3,GFRA2,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,LAYN,PCDH9,FXYD1,PMP22,SH3KBP1,TMEM255A,ROBO2,PDZD2,SULF2,ZEB1,VSNL1,ZNF711" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500 facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500 Gudmap RNAseq 1.56E-05 7.59E-02 9.38E-05 8.50E-04 169 1204 "PLEKHH1,KIAA1211,KLHL13,HACE1,KIAA1324,PDZD4,AMPH,LRCH2,MYH7B,EPB41L5,VAT1L,BCAS1,TMEFF1,ARHGDIG,KIF1A,BARD1,BCHE,NRP2,ZNF599,PROM1,WASF1,MYRF,CA4,CA12,THSD7A,PTBP2,MTMR7,CDH2,LRWD1,CACNA2D2,NRXN3,CLCN3,FAM19A5,C4orf33,CNTFR,BAG4,NECTIN3,SLC35F1,FAM171B,CRMP1,CNTNAP2,FAM169A,CTH,GREB1,TMEM170A,AIF1L,DMD,E2F5,SEZ6L2,TSPAN5,EDN1,PLEKHA1,EMX2,ENO2,EPHB1,EXTL2,ADGRV1,REEP2,TBC1D16,CEP78,SPSB4,FGF13,FHL1,ZMYND15,NOP56,SYT3,CINP,FAM49B,PRELID3A,FUT9,RUNDC3A,DBF4,TOX3,CBX1,GPD2,CCDC184,LPAR4,STMN2,RNF165,PSIP1,TOX2,FRMD5,HLF,CFAP126,HSF2,LRRCC1,SLC35G1,IPO5,KTN1,CAMK2N2,MAP6,MAT2A,AQP11,MEST,MIA2,MSI1,MYCN,VWA2,NOVA2,NRCAM,PDE1B,FAM98B,OLA1,SNX10,PKM,PSAT1,POLR2F,FSD1,PPP1R1A,PKIA,PRKCB,MAPK4,RELN,GDPD2,ELOVL2,SPDL1,ZIK1,PTPN13,EML5,NKAIN1,CEP97,CCDC40,FAM184A,FIGN,NUDT11,RPL15,RTN1,SALL1,MAPK12,ZFP2,HSPA4L,KIF21A,PPM1E,FHOD3,CCDC92,PPP4R3A,PKNOX2,KDM4B,SOX11,PBLD,ZC4H2,MTCL1,WSCD1,CUX2,C18orf54,ITGB3BP,AKTIP,RELL2,ACTR6,BEX4,RGMB,CA14,RPRM,UBE3A,XPO1,KCNT2,ZFP41,TMEM237,DPYSL5,SMARCAD1,SLC38A1,STOX2,PCBP4,WNK3,AMN1,FZD3,PHTF2,NETO2,SPATA13" Coexpression Atlas GSM605856_500 "Myeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.60E-05 7.78E-02 9.60E-05 8.71E-04 73 433 "ALCAM,ABCD2,GAS7,APOC2,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,CD38,MS4A7,B4GALT6,TPP1,LY86,GDA,CSF1R,CST3,CYBB,MYADM,DBI,FAM78B,EDNRB,PLXNC1,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FGFR1,PCYOX1,FOLR2,AK8,TPPP3,GALC,GATM,HPGDS,GLUL,IRAK3,HNMT,IGF1,LRRC25,ITGAM,LAMP2,LIFR,MITF,MSR1,NCF2,P2RX7,P2RY1,TREM2,PLTP,PMP22,LRP12,PILRA,DRAM2,RASGEF1B,GDPD1,PID1,C1orf54,SLC11A1,SPP1,RGL1,SULF2,SLC37A2,KIAA0930,TPCN2,TLR4,TNS1,LAT2,AGMO,PLD4,MARCH8" Coexpression Atlas GSM605834_500 "Myeloid Cells, DC.8-4-11b-.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.61E-05 7.83E-02 9.66E-05 8.75E-04 69 403 "ACTN1,FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,ST3GAL5,CD86,LARGE1,UBE2L6,ARHGAP22,LY86,SLC4A8,CDC42BPB,OSBPL3,CST3,CYBB,GUCD1,PLPPR4,ARRDC4,PLXNC1,ENO2,ZMYND15,TMEM107,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,HMGCR,HSF2,IRF8,SCIN,INSM1,JAK2,KIT,KTN1,NCOA7,ASPRV1,MYO9A,PFKFB3,CCSER2,PLCL1,EML5,ROGDI,ZDHHC14,LRRK2,RTN1,SEMA6D,ARHGEF40,CCDC88A,SAMSN1,SULF2,TMEM150C,ARC,SIRT1,SLC44A1,TRPM2,CLIP2,ZBTB38,SPIRE1,ITM2C,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_500_k5 DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.66E-05 8.05E-02 9.91E-05 8.98E-04 24 93 "ADRB2,GPR146,LDLRAD4,LDB2,CD86,CSF1R,IGSF6,F8,FCGR1A,FYB1,GATM,GGTA1P,LYVE1,NCKAP1L,PIK3AP1,TM6SF1,MSR1,P2RY13,SLA,TEK,TLR4,NPL,VAV1,FAM13C" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k1 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.69E-05 8.19E-02 1.01E-04 9.13E-04 33 149 "ADCY5,PI16,APC,ADAM23,CACNA2D1,ENTPD2,CFL2,MFAP3L,CHRDL1,CPEB2,HIPK3,CALCRL,MRVI1,NRN1,DLC1,PDLIM5,GCNT2,GSN,MBP,PIK3C2A,KANSL1,REV3L,SCN7A,ZHX3,MYCBP2,SYN2,TACC1,ERCC6L2,TBC1D15,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.73E-05 8.42E-02 1.03E-04 9.37E-04 17 54 "SPARCL1,ALCAM,ARHGAP20,EDNRA,EGFR,GFRA2,FREM1,GLI2,GUCY1A1,IGF1,PCDH9,LAMA1,TMEM255A,ROBO2,MEG3,PEG10,VSNL1" Coexpression Atlas Lungmap Mouse Lung PND1 Pericyte Subtype All subclasses Lungmap Mouse Lung PND1 Pericyte Subtype All subclasses Lungmap CCHMC 1.77E-05 8.58E-02 1.05E-04 9.55E-04 39 189 "SYN3,NDRG2,SPARCL1,SEPT7,CDH2,ARHGEF6,CST3,EBF1,EDNRA,HEYL,RASGRP2,RASL12,HIGD1B,HTATSF1,FERMT2,GUCY1A1,GUCY1B1,ELOVL5,KLHL23,KCNK3,LIMS1,MAPT,MATN2,ENPP2,FXYD1,PCDH18,SEPT4,NKAIN4,C1orf54,EMID1,MEG3,PEAR1,BTBD3,PDZD2,TACC1,PJA1,TNS1,TUBA1A,TMEM178A" Coexpression Atlas GSM399440_500 "B cells, B.FrF.BM, CD19+ IgM+ AA4.1- HSA+, Bone marrow, avg-3" "Immgen.org, GSE15907" 1.79E-05 8.71E-02 1.07E-04 9.68E-04 64 367 "ADRB2,ZNF608,TXNDC16,CARNS1,FGD2,ATP6V0A1,BTK,CACNA1I,HIP1R,CD38,CDC25B,LY86,CNN3,CSNK1G3,PPP1R16B,KIAA0040,RUBCN,CYBB,HDAC9,RIPOR2,GUCD1,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,TLR7,CHST15,HVCN1,MALT1,RAB30,DCLK2,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,GPR155,MEF2C,MYO5A,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,LRRK2,RASA3,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,STAC2,MGRN1,TCF4,CYB561A3,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05 ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.81E-05 8.78E-02 1.08E-04 9.75E-04 54 294 "AXIN2,ADORA1,ALCAM,PCDH10,MARK4,RASL11B,RIPK1,DOCK11,NRP2,BMP7,CALM1,NOG,NGEF,COL9A3,COL11A2,NRG2,HAPLN1,PDE4DIP,BOC,DOCK4,LYPD1,CDON,EDIL3,EDNRA,MTSS1L,TMEM132C,FECH,RASSF8,ZIC5,ITPKB,KIT,CLEC18A,MAP2,MATN2,SAMD5,NPY,PDE1B,PLTP,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,PRODH,RELN,PTPRD,ZFHX4,SLC12A2,DOK5,NMNAT2,SPP1,COBL,ZIC2,SEMA3B,DOCK8" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k4_500 kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.82E-05 8.85E-02 1.08E-04 9.80E-04 40 196 "RNF157,AMPH,BCL7A,BMP7,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,GSDME,SNAP91,DTNA,EDNRA,ETV1,RRAGB,EYA1,FGFR1,MAD2L2,SCARA3,IGSF5,FREM1,CNTRL,FAM107A,HAS2,NEGR1,MEST,NME4,CNTN3,TSPY26P,SALL1,SLC4A3,GKAP1,ADAMTS17,CUX2,PCDHB9,SLC38A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.86E-05 9.04E-02 1.10E-04 1.00E-03 19 65 "VAT1L,CADPS,RNF182,DCLK1,CLGN,CNR1,CRYM,SCRN1,JAKMIP2,EYA1,NBEA,PPARGC1A,NDP,GPR85,TRHDE,FIGN,ANKRD6,PCDHB10,PCDHB3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.89E-05 9.18E-02 1.12E-04 1.01E-03 28 118 "KLHL13,LGR5,CDC14B,PPP4R4,IGDCC4,BOC,TSPAN5,NRN1,IP6K2,AFF2,ZMAT1,TRAF3IP2,KLHL23,MAP2,MATN2,NEXMIF,PCDH18,PPP3CC,REV3L,HUNK,ATF7IP,UHRF1BP1L,ST5,ADGRL3,OBSL1,ZFPM2,TRPS1,TST" Coexpression Atlas facebase_RNAseq_e10.5_MandArch_2500 facebase_RNAseq_e10.5_MandArch_2500 Gudmap RNAseq 1.90E-05 9.24E-02 1.12E-04 1.02E-03 200 1470 "ABCF1,KIAA1324,CEP126,LRCH2,MYH7B,APC,DYNLL1,SLC4A4,SEC11C,NRP2,BLM,ZNF599,PROM1,BMPR1B,NAE1,CACNA1G,CA12,PTBP2,RUNX1T1,CCNH,USP2,C1orf52,LRBA,SEPT7,KCNAB3,CRLF1,C4orf33,CNR1,IQCK,COL9A1,TBPL1,AHCTF1,IGDCC3,HAPLN1,GDA,CLIP3,CRYM,IPCEF1,VCAN,FAM169A,DZIP3,PHF14,PNPLA8,GREB1,LIN54,PITPNC1,GSDME,DDX46,MTX3,USP3,CASP8AP2,DUSP9,E2F5,EDN3,EDNRA,OPTN,EIF5,EIF1,EPB41,COQ7,LRRC17,ERBB4,CEP85L,CDKL3,ETV1,KATNAL1,EYA1,NRN1,NSRP1,CORO2B,RACK1,TMEM164,UBE2E3,MEX3B,AFF2,NOP56,WDR83,SMC2,PRELID3A,MPP6,HIGD1B,GFRA2,HPGDS,DBF4,CBX1,KCNMB4,LPAR4,CNTRL,PRDM5,CIT,PSIP1,ATOH8,MUM1,RASSF8,HSF2,SMAP1,LRRCC1,KCNJ5,KCNJ16,KIF2A,KIT,LIG4,HECTD2,MEST,MID1,MITF,MXI1,MYCN,LINC00672,TCEAL5,NBL1,NNAT,CNOT4,SMIM11A,PDCD2,PDE4D,ENPP2,FAM98B,OLA1,SERPINI1,FA2H,RASGEF1B,CEP41,GDPD2,CNTLN,ELOVL2,SPDL1,ZIK1,NKAIN1,RAD17,CCDC40,BEND5,RBBP8,RDX,ZMAT4,FIGN,RGS4,NUDT11,SETD5,RPS20,RTN1,CCDC112,ZFP2,SH3BGR,SH3GL3,CHD9,FHOD3,ST6GAL1,CNKSR2,DZIP1,PREX2,DHX30,PKNOX2,ARHGEF40,CCDC88A,ZNF334,RBM34,RBM26,SS18,ERBIN,DNAJC9,TAF9,TAL1,SATB2,CUX2,ZEB1,NSD1,TEK,ITGB3BP,ACTR6,ASXL3,TMPO,BEX4,R3HDM1,PIK3R5,C9orf85,SYNPO2,METTL3,PDSS1,STXBP4,TRPS1,CA14,UBE3A,USP1,ZNF711,ZNF23,ZFP41,AGMO,ZNF184,EML6,SMARCAD1,EMSY,EVI5,PPP1R3F,MRPL47,SMIM8,FXR1,NETO2,AP3B2,ST8SIA2" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.90E-05 9.24E-02 1.12E-04 1.02E-03 42 210 "TAOK1,LCORL,MADD,ZNF583,AKAP5,DZIP3,APPL1,HDAC9,TMEM130,SACS,CPEB2,CD320,SCML2,PDLIM5,TDRKH,TPPP,KCND2,HECTD2,KITLG,GPR137C,C19orf57,PPP3CC,ANKHD1,EML5,ATP8B4,FNIP1,HSPA4L,WDR47,CPEB4,ZNF667,SP4,ARHGAP26,LARP4,VPS13A,SYN2,SIRT1,RUNDC3B,UGT8,VSNL1,LYPD6,PHTF2,RSPRY1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200_k2 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.90E-05 9.25E-02 1.12E-04 1.02E-03 22 82 "SORCS2,C1QTNF3,SYT13,IL33,RUNX1T1,LDB2,CDH2,FAM171B,BOC,EBF1,SEMA3D,TMTC1,RAB40B,UBE2QL1,KCND2,PIK3R1,PTPRD,FAT4,CSRNP3,MAPKBP1,TROVE2,SSBP2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F-2X DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-2fold-vs-F_top305_305 Gudmap Mouse MOE430.2 1.93E-05 9.35E-02 1.13E-04 1.03E-03 50 266 "KDM5D,RNF157,USP31,DCLK1,ZNF445,COL9A1,ABI3BP,RBM39,OSBPL3,APPL1,PUM1,ALKBH8,EBF1,EIF5,FKTN,MEX3B,OGA,RAPGEF6,RAB40B,GPD2,LPAR4,MAP4K5,RASSF8,IL6ST,PAXBP1,MEIS2,MMP16,MYH3,PCDH8,PIK3R1,KANSL1,GRAMD1C,PTPRG,RGS4,PBRM1,CLIP1,FNIP1,TRA2B,KIF21A,SEPHS1,SLC14A1,TCF4,AP4E1,RGMB,TRPS1,SSBP2,TTC3,PHTF2,ZDHHC20,SOCS4" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.93E-05 9.39E-02 1.14E-04 1.03E-03 59 331 "EMILIN3,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,ARHGEF6,ABI3BP,ANKRD44,SNCAIP,DNM1,ELN,LRRC17,FCGRT,TRIM16,STAU2,TVP23A,ZMAT1,ZNF276,GRIK4,SYNPO,CREG2,SRSF12,MSR1,TCEAL5,FXYD7,NFIX,ZNF827,CNTN3,PDE4D,SDK2,EPB41L4B,CCDC144B,CNTLN,ACSS3,IQSEC3,BEND5,ZFHX4,MRAP2,LRRK2,DGLUCY,SH3GL3,SLC8A1,PDZRN3,ADAMTS17,PLCB1,ADGRL3,SATB2,PHF24,PIK3R5,SYNPO2,TRPS1,TSPAN11,ZNF32,NAV3,KLHDC1" Coexpression Atlas GSM399362_500 "alpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3" "Immgen.org, GSE15907" 1.95E-05 9.49E-02 1.15E-04 1.04E-03 55 302 "ACTN1,ADCY6,AXIN2,OSBPL8,ARHGAP20,PITPNM2,SFMBT2,ARNTL,FUBP1,ARHGEF1,CNN3,ARHGEF6,AKAP12,LRIG1,IPCEF1,SIPA1L1,ABCC5,RASGRP1,FYN,CHL1,RAPGEF6,KCNMB4,DCLK2,BACH2,IL6ST,ITPKB,STMN1,HECTD2,ZNF827,PDE4D,TMIE,SH3KBP1,BEND5,REV3L,RGS3,PBRM1,ZNF354C,SATB1,GALNT10,FAM102A,ST6GAL1,DZIP1,ST8SIA1,TET1,SP4,ERC1,KLHL4,TIAM1,BHLHB9,KAT6B,TRIO,SSBP2,TTC3,MAP3K12,SENP7" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.96E-05 9.53E-02 1.15E-04 1.05E-03 45 231 "FMNL2,KLHL13,LGR5,CDC14B,PPP4R4,NUMB,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,AASS,EMX2,MTSS1L,ABCA8,AFF2,BVES,SHISA6,KCND2,KLHL23,KITLG,AFF1,SERPINI1,PTPN13,REV3L,HUNK,RASA3,ST8SIA1,SLC4A3,KDM3A,UHRF1BP1L,ST5,ADGRL3,OBSL1,CCDC173,DNAH7,ZFPM2,ACTR6,TST,LYPD6,DPF3" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k3 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.99E-05 9.68E-02 1.17E-04 1.06E-03 26 106 "RNF157,FAM135A,ADAM23,KALRN,MAP4K4,CRMP1,PPP1R16B,SPOCK2,BRINP1,SNAP91,SLC43A2,CHL1,PCDH8,EPB41L4B,CEP41,DIRAS2,GAL3ST4,ZMAT4,FIGN,RPS6KA2,HUNK,MAPK12,ZNF334,CLSTN2,ASXL3,TPM2" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k4_1000 kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.05E-05 9.93E-02 1.20E-04 1.09E-03 57 317 "KLHL32,ADORA1,ZNF608,PCDH19,CEP126,VAT1L,BARD1,BCL7A,BLM,CACNA1G,SOCS6,SLIT2,GREB1,CENPL,GSDME,SV2B,RAB39B,EMX2,HSD17B14,EPB41,POLR1B,MEX3B,MPP6,MTHFD2,IGSF5,TOX3,KDM2B,ADGRA3,CLEC18A,TM6SF1,POC1B,MSI1,MYCN,NPY,PRTG,SDK2,SPDL1,RBBP6,ROBO1,GLDN,CCDC112,SH3BGR,SH3GL3,CNKSR2,SEPHS1,ATF7IP,CMTR2,SOX11,NUDT10,TACR1,CUX2,HEY1,TRPS1,SLC38A1,ADAMTS9,FZD3,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k3 DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.06E-05 1.00E-01 1.21E-04 1.09E-03 40 197 "NCKAP5,EPB41L5,PROM1,WASF1,CALB1,LRBA,CDO1,CBARP,FAM149A,IPCEF1,ERC2,CTH,EMX2,SYNCRIP,EFCAB2,PPARGC1A,TCERG1,CCDC184,SCIN,AQP11,CNOT4,CLDN11,PCDH8,PDE1C,PLXNB1,PTPRD,PTX3,RBBP8,EMID1,SCN8A,HKDC1,PCDHB9,CHST5,UGT8,LYPD6,MAP3K12,VPS35L,PHTF2,NETO2,SOCS4" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k5 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.06E-05 1.00E-01 1.21E-04 1.09E-03 40 197 "NDRG2,SRPX,ARHGAP20,PCDH10,PTCH2,ADGRB3,IL33,LDB2,DCLK1,NRXN3,COL4A5,CSF1R,PLCXD3,RIPOR2,CDON,EDNRA,SEMA3D,TMEM132C,FCGRT,FGF1,GAD1,TNRC6A,GLUL,HTATSF1,PARD3B,GSN,RASSF8,MATN2,PCSK5,NALCN,PIK3R1,PTN,C1orf54,LGI2,MRAP2,MEG3,CXXC4,PCDHB9,HIF3A,VLDLR" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.07E-05 1.01E-01 1.21E-04 1.10E-03 20 71 "HAP1,EPHB1,ADGRV1,REEP2,SPSB4,STMN2,RNF165,TOX2,FRMD5,ZIC5,NRCAM,MAPK10,RTN1,HSPA4L,WSCD1,MGAT5B,ZIC1,DPYSL5,FZD3,SPATA13" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.09E-05 1.02E-01 1.22E-04 1.11E-03 32 144 "KLHL13,SPARCL1,LGR5,PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,LRRC17,NRN1,FLNC,AFF2,GATM,FREM1,GUCY1A1,KCND2,KLHL23,MAP2,MATN2,PCDH9,PCDH18,TMEM255A,ROBO2,ADGRL3,ZFPM2,VSNL1,LYPD6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-05 1.06E-01 1.27E-04 1.15E-03 61 347 "SPARCL1,SEC11C,BMP7,ARHGEF7,THSD7A,VXN,PRC1,SEPT7,CDO1,SOCS6,IGDCC3,LYPD1,EDNRB,EEF1D,PHF20L1,ADGRV1,FAM198B,FDFT1,FGFR3,BAIAP2,SMC2,SPECC1,PDLIM5,MEGF10,STMN2,TOX2,ELOVL5,HMGCR,LSAMP,MEST,MN1,MSI1,NELL2,NNAT,NPTX2,NTRK2,CNTN3,PCDH8,PDPK1,IRX1,MAPK4,LAMA1,PTCH1,ZIM2-AS1,C1orf109,PTX3,MEG3,SALL1,HES6,PUF60,ARX,LIMCH1,SOX3,NMNAT2,SYNE2,ZEB1,TCF12,NSD1,TMPO,WNT7A,LAMP5" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.23E-05 1.08E-01 1.30E-04 1.18E-03 21 77 "ACHE,APLP1,ARHGDIG,ATP1A3,CCK,CLTB,CNTFR,CNRIP1,SLC35F1,NELFCD,TMEM107,KCNMB4,GP1BB,ACOT7,NPY,GNG2,NLGN3,FXYD1,POLR2F,ELOVL2,S100B" Coexpression Atlas PCBC_MESO-5_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 2.25E-05 1.09E-01 1.31E-04 1.19E-03 141 979 "KCNH8,UNC79,PDZD4,DPP10,APOC1,LGR5,TMEFF1,ARSE,RASL11B,KIF1A,BMP7,BTK,C5,MYRF,CCK,USP2,SYNGR3,L3MBTL4,PLEKHB1,FAM189A2,FAM19A5,SULT4A1,IGLON5,CNR1,COL9A1,COL9A3,AKAP5,GAL3ST1,MYRIP,NRG2,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGEF4,ARHGAP24,KIF26A,ELMO1,SV2B,SPOCK3,DPP6,FAM78B,CNNM1,RASGRP1,HSD17B14,RCAN2,ERBB4,RASL12,ADGRV1,FGFR3,RASL10A,MEGF10,HRASLS5,GABRA3,CHL1,GABRB3,GAD1,RAPGEF6,SYT17,GATM,PCDH17,PPARGC1A,GNAL,GPR37,TMEM121B,STMN2,GRM2,PTPRT,FAM222A,HAS2,PADI2,NXPH3,IGFBPL1,HP,SHISA6,LRRTM1,C2CD4C,KCNF1,KIT,MATK,MATN3,MSR1,MYT1,NNAT,PAX6,PCDH8,SERPINI1,SEMA5B,SNX10,JAKMIP1,PNMA3,PDZRN4,PILRA,FA2H,RASGEF1B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,KHDRBS2,PRIMA1,LGI2,MRAP2,HUNK,SALL1,TMEM200C,CNKSR2,ANKRD6,CABCOCO1,MYO16,SOX15,HECW1,PEG10,MCF2L2,NFASC,SSTR2,TMEM150C,COBL,CUX2,PHF24,FAM189A1,GALNT17,FAM124A,RIMBP2,PIK3R5,TRO,TRPM2,CA14,RPRM,VIPR2,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO bone marrow_cfr-2X-p05 ECTO blastocyst_vs_ECTO bone marrow-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.25E-05 1.09E-01 1.31E-04 1.19E-03 33 151 "AXIN2,ADORA1,PCDH10,RASL11B,NRP2,LARGE1,NOG,SLIT2,IGLON5,COL9A3,COL11A2,HAPLN1,PDE4DIP,LYPD1,EDIL3,EDNRA,EPHB1,TMEM132C,ITPKB,KIT,CLEC18A,SAMD5,NPY,IRX1,ZFHX4-AS1,LRRN3,RELN,GDPD2,TNFRSF19,TMEM200C,SPP1,DNMBP,LMF1" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_500 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.29E-05 1.11E-01 1.33E-04 1.20E-03 52 282 "HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,NRP2,LDB2,CD38,MS4A7,ABCG2,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,CYBB,ELMO1,EBF1,EDNRB,CALCRL,RASGRP2,DLC1,FLT1,PDLIM5,FYB1,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,MAP4K5,NCKAP1L,ICA1,LMO2,TM6SF1,MEF2C,SNRK,PTPRB,TMEM255A,C1orf54,SEMA6D,PREX2,LIMCH1,PEG10,THSD1,KLHL4,TEK,NAV3,FAM13C,DOCK8" Coexpression Atlas gudmap_kidney_e15.5_Podocyte_MafB_1000 kidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.31E-05 1.12E-01 1.34E-04 1.21E-03 121 816 "ALCAM,EPB41L5,ASPA,SLC4A4,BCL7A,PROM1,BMPR1B,CACNA1G,IL33,CA4,CA8,CACNA2D1,CALB1,THSD7A,CLDN10,LRBA,CDO1,SOCS6,SLIT2,RAB28,CNTFR,AKAP12,CRYM,SNCAIP,VCAN,CTH,ARHGAP24,SCRN1,AIF1L,HEPH,GSDME,MTX3,FAM107B,ARRDC4,E2F5,SEMA3D,CALCRL,LRRC17,ERBB4,PIPOX,EYA1,SH3YL1,ST3GAL6,UFM1,FAM49B,ST6GALNAC3,FUT9,IQGAP2,SYT17,IGSF5,FREM1,GHR,PPARGC1A,PARD3B,GUCY1A1,HAS2,ZDHHC15,NEGR1,KCNJ16,CLEC18A,LYPLAL1,AQP11,MATN2,TM6SF1,MYO6,MYO9A,NELL2,NME4,NOVA1,PDE4D,ENPP2,RETREG1,PLCL1,SCHIP1,DRAM2,MINDY2,LAMA1,PTH1R,ELOVL2,PTN,PTPN13,PTPRO,PTX3,TUG1,FAM184A,ERI2,MORC4,SUGCT,ROBO2,TRAPPC13,SALL1,KIF21A,FERMT1,FHOD3,CNKSR2,SLA,CPEB4,NXT2,NUDT10,ADAMTS17,PLCB1,TMEM150C,TAF9,KLHL4,SATB2,CUX2,TEK,NPL,TPM2,TRPS1,UGT8,FLRT2,PLEKHH2,VLDLR,ZNF708,KCNT2,SPIRE1,SLC38A1,ADAMTS9,TMEM178A,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k3_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.38E-05 1.16E-01 1.37E-04 1.25E-03 26 107 "SPARCL1,ALCAM,ARHGAP20,MPDZ,CACNA1G,ARHGEF25,ZNF521,HAPLN1,EDNRA,EGFR,LRRC17,ST6GALNAC3,GFRA2,FREM1,LPAR4,GUCY1A1,GUCY1B1,IGF1,LAYN,FXYD1,TMEM255A,ROBO2,PEG10,SULF2,VSNL1,ZNF711" Coexpression Atlas GSM538216_500 "B cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 2.38E-05 1.16E-01 1.37E-04 1.25E-03 61 348 "ZNF608,TXNDC16,FGD2,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,RUBCN,CYBB,HDAC9,RIPOR2,ARHGAP24,GUCD1,SLC12A6,EBF1,SNX29,FRY,SRPK3,RASGRP2,DENND4A,TLR7,CHST15,HVCN1,ACSS1,MALT1,RAB30,IRAK3,BACH2,IRF8,IL12A,LIFR,LMO2,PIK3AP1,GPR155,MEF2C,MYO5A,NUCB2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,ZDHHC14,LRRK2,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,CYB561A3,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas facebase_RNAseq_e9.5_OlfPlac_2500_K3 facebase_RNAseq_e9.5_OlfPlac_2500_K3 Gudmap RNAseq 2.39E-05 1.16E-01 1.38E-04 1.25E-03 166 1188 "TMCC3,AXIN2,KIAA1211,KLHL13,PCDH19,ZNF687,DOC2A,TRMT9B,FGD2,MYH7B,NT5C3B,TMEFF1,ARRB2,BCHE,BLM,ZNF599,PROM1,BMP7,WASF1,CA4,CA12,HAP1,PTBP2,MTMR7,CBFA2T2,ARHGEF2,CDH2,LRWD1,TBRG4,CACNA2D2,CBARP,MYL6B,FAM19A5,HOMER3,CNTFR,PCYT1B,BAG4,ZNF385A,HAPLN1,CNTNAP2,PLXNA4,FAM169A,GREB1,KATNAL2,AIF1L,USP3,CDON,DTNA,DUSP9,FARSB,E2F5,TSPAN5,YAF2,EIF4G1,RGS17,EMX2,EPB41,ETV1,EYA1,REEP2,CEP78,POLR1B,SPSB4,FGF12,FHL1,SYT3,NELFCD,POMT1,TMEM107,CINP,PDLIM5,KHDRBS3,FUT9,MTHFD2,TCERG1,DBF4,GLI2,TOX3,GLUL,STARD3,KIAA1958,GPD2,ZNF496,RNF165,PSIP1,FAM107A,FAM222A,HAS2,FRMD5,HSF2,LRRC75A,SHISAL1,METTL21A,KCNH2,KIT,AQP11,ADAM11,MEIS1,MEST,KCTD6,AFDN,MSI1,TAGLN3,MXI1,MYCN,NNAT,PDPK1,SNX10,RETREG1,PKM,GPSM2,SLC25A23,PSAT1,PPP5C,PRODH,GDPD1,LAMA1,ELOVL2,ZIK1,PTPN13,EML5,NKAIN1,CCDC40,ZMAT4,DPF2,FIGN,RFX3,NUDT11,GSTCD,RPS6KA2,HUNK,RTN1,TRAPPC13,SALL1,MAPK12,SATB1,KIF21A,ST6GAL1,CCDC92,PKNOX2,IFT122,SOX11,SPTB,KANK1,ANKRD28,MMS19,DOCK9,SIRT1,ITGB3BP,HEY1,CA14,HIRA,USP1,KLC2,ZFP41,TFIP11,MEIS3,DHX33,SLC38A1,TUBA1A,ADAMTS9,PCBP4,WNK2,FZD3,TTC7A,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-vs-M DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-vs-M_top280_280 Gudmap Mouse MOE430.2 2.40E-05 1.16E-01 1.38E-04 1.25E-03 49 261 "AXIN2,RNF150,ANK2,CDC14B,RASL11B,DYNLL1,BLM,LARGE1,CLGN,AKAP7,SLC35F1,FAM171B,RIMS2,CENPL,SCRN1,PITPNC1,RHOBTB1,ANKRD46,TBC1D16,SCARA3,CHL1,GAD1,FAM120B,FREM1,PPARGC1A,GLI2,SYNPO,CELF5,GPR155,PPM1L,NDP,NEK1,VWA2,PFKFB3,PEX2,TUG1,SGK1,PPM1E,FRMPD1,DZIP1,ATF7IP,CLSTN2,ZC3H4,SYNE2,CAMTA1,TIMP4,ASXL3,SYNPO2,WNT7A" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 2.41E-05 1.17E-01 1.38E-04 1.25E-03 79 484 "NDRG2,CCDC85A,OSBPL8,ARHGAP20,LTBP4,GPRASP2,CDK10,ADGRB2,ZNF599,BMPR1B,CBLN1,LRBA,CDO1,CRLF1,LHX2,HOMER3,COL9A1,IGDCC3,HAPLN1,CRYM,CSF1R,GREB1,DLX1,DUSP9,SEMA3D,EGFR,ELN,EMX2,LRRC17,ADGRV1,FCGRT,FGF11,FYB1,PCDH17,PPARGC1A,ZNF276,MAP7D2,GSN,SYNPO,KCNH2,MEIS1,MEIS2,SRSF12,KITLG,MITF,MSI1,MYCN,NCAM2,NELL2,NFIX,NNAT,CNTN3,PAX6,PCDH9,PRTG,PGAM2,PKM,PLCL1,NECAB2,POLR2F,IRX1,PRODH,ZMAT4,FIGN,LIMCH1,SOX11,ZSWIM8,ADGRL3,PHF24,FAM189A1,CA14,HSPBP1,TSPAN11,CLIP2,LAMP5,ZXDA,ADAMTS9,PCBP4,SENP7" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.41E-05 1.17E-01 1.38E-04 1.25E-03 23 89 "AMPH,EPB41L5,VAT1L,ZSCAN18,CACNA2D1,FAM19A5,ZFP28,CRYM,SIPA1L1,EYA1,ST3GAL6,FGFR1,SCARA3,MEGF10,FAM19A2,FAM107A,HAS2,PRTG,CEP41,RPS6KA2,SALL1,ANKRD6,HEY1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.41E-05 1.17E-01 1.38E-04 1.25E-03 23 89 "TAOK1,DPP10,CADPS,CACNA1B,CACNA2D1,CHGB,PLCXD3,GRIN3A,DLC1,FOXF2,STMN2,IFI16,MAP4,NEFM,CLDN11,NALCN,MAPK10,PRPH,RGS4,ZFHX4,RTN1,SNAP25,RGMB" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k1 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.43E-05 1.18E-01 1.39E-04 1.26E-03 54 297 "KLHL32,ALCAM,SEMA7A,EPB41L5,ST3GAL5,THSD7A,KALRN,HIP1R,LRRFIP1,CACNA2D2,RNF14,RIPOR2,ARHGAP24,AIF1L,ALKBH8,TMCC2,CD99L2,OPTN,SRPK3,RASGRP2,CORO2B,ST3GAL6,CGREF1,IQGAP2,SRRM4,IGSF5,GGT5,PARD3B,SYNPO,HP,MAPT,LYRM9,PDE4B,SERPINI1,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,FAM184A,DUSP15,ROBO2,SCN7A,GALNT10,ANKRD6,SNCA,DDN,STX1A,TMEM150C,PDLIM2,ARHGAP9,ZNF23,TMEM178A,RNF170" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 2.44E-05 1.19E-01 1.40E-04 1.27E-03 47 247 "ABHD6,GPRASP2,CDK10,ADAM23,BMPR1B,SCAPER,CACNA2D1,LRBA,CDO1,CRLF1,DIS3L,CLIP3,PHF14,DDX46,ELN,EPB41,LRRC17,CORO2B,FCGRT,FDFT1,HPCAL4,ZNF276,GSN,SYNPO,KNDC1,LRRCC1,TM6SF1,MEIS2,SRSF12,MXI1,NFIX,GPSM2,DIRAS2,CNTLN,IQSEC3,ENOX1,RBBP8,DOP1A,TRERF1,BDP1,ANKRD28,PHF24,STXBP4,TRPS1,USP1,LYPD6,ST8SIA2" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K3 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K3 Gudmap RNAseq 2.45E-05 1.19E-01 1.40E-04 1.27E-03 46 240 "ACHE,C1QTNF1,PDE8B,MYOM1,ARHGEF6,DGKB,ZNF804A,LRRC17,EPHB1,TLR7,RASL12,ST3GAL6,CHST15,FCGRT,TPPP3,HIGD1B,LOXL3,STON1,GUCY1A1,GUCY1B1,IL6R,IL6ST,TTYH2,LAYN,P2RX7,PDE3A,ABCB1,PLCL1,PLEC,FXYD1,PPARA,PTN,ZMAT4,SGK1,LIMS2,SLC8A1,NKAIN2,PDLIM2,TNS2,ENHO,TLR4,TNS1,ZBTB38,PLSCR4,FAM13C,MSRB3" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K1 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.47E-05 1.20E-01 1.41E-04 1.28E-03 77 469 "ABCF1,CEP126,PARG,APC,ZFYVE28,ADAM23,BBS2,ZNF599,DST,THSD7A,PTBP2,CCNT1,SLC16A4,CCPG1,C4orf33,HECTD1,MAP4K4,TBPL1,IGDCC3,CLIP3,SUSD5,FAM169A,DZIP3,TBC1D5,DDX46,FAM107B,DUSP9,PHF20L1,PAN3,EPB41,CEP85L,NSRP1,SEC24B,TMEM164,SMC2,MPP6,HIGD1B,C15orf41,ARFIP1,TCERG1,ZNF638,FERMT2,CIT,LRRCC1,KLHL23,TM6SF1,MYO6,PIK3C2A,EXOSC10,CEP41,MASP1,GDPD2,CCDC40,RAP1GDS1,RBBP8,ZFP30,PREX2,SEPHS1,TET1,INTS9,SPATA7,BDP1,PRRC2C,DNAJC9,ANKRD28,TAF9,TCF4,C18orf54,LRRC8A,PARD3,STXBP4,ZKSCAN5,XRCC4,ZNF23,EML6,HNRNPA3,FXR1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.49E-05 1.21E-01 1.42E-04 1.28E-03 14 40 "RUNX1T1,KIAA0408,EMX2,NRN1,TUBB3,NSG1,STMN2,GRIA2,TAGLN3,NEFM,NNAT,NOVA1,MEG3,RTN1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.49E-05 1.21E-01 1.42E-04 1.28E-03 14 40 "CACNA2D1,CFL2,VCAN,SYNCRIP,SMC2,PDLIM5,FERMT2,MKLN1,PIK3C2A,KANSL1,REV3L,ERCC6L2,RGMB,SSBP2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.49E-05 1.21E-01 1.42E-04 1.28E-03 14 40 "RUNX1T1,KIAA0408,EMX2,NRN1,TUBB3,NSG1,STMN2,GRIA2,TAGLN3,NEFM,NNAT,NOVA1,MEG3,RTN1" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.53E-05 1.23E-01 1.44E-04 1.31E-03 35 165 "ALCAM,ARHGAP20,LTBP4,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SLIT2,ZNF521,VCAN,RIPOR2,ARMCX2,EDNRA,EGFR,LRRC17,DLC1,FLNC,GFRA2,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,PCDH9,PLTP,LRRN3,LAMA1,PTCH1,PTN,ROBO2,ARMH4,SULF2,TPM1,STOX2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.54E-05 1.23E-01 1.44E-04 1.31E-03 56 312 "RNF150,ARHGAP20,RASL11B,TMEM108,MYRF,KALRN,CBLN1,SLIT2,CNTFR,AKAP5,CLIP3,VCAN,TIAM2,DNM1,EDNRA,SEMA3D,EGFR,C8orf37,FLNC,NSG1,TRAF3IP2,DENND2A,FREM1,CSDC2,GHR,GLI2,GUCY1A1,HAS2,TCEAL6,NKD1,MAP2,MATN2,MEIS1,TCEAL5,ZC3H12B,NEFM,NME4,PIK3R1,PCDH18,LAMA1,PTN,PTX3,RADX,ROBO2,MEG3,PKNOX2,SULF2,KLHL7,ASXL3,TPM1,TRPS1,SSBP2,PLEKHH2,ZFP37,STOX2,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k1 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.58E-05 1.25E-01 1.46E-04 1.32E-03 39 192 "ADCY5,SRPX,PI16,ATP2A2,MYOM1,NRP2,DMPK,CPEB2,DTNA,MRVI1,FHL1,FLNC,IGSF5,PRUNE2,BVES,IL6ST,ALDH1L2,NPTX2,PRKAB2,PRKCB,RYR3,SCN7A,STUM,SH3BGR,FHOD3,LIMS2,FNBP1,DBNDD2,ENHO,TNS1,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,FAM13C,ACTR3B,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.58E-05 1.25E-01 1.46E-04 1.32E-03 39 192 "ABCF1,PCDH19,MAGEE2,BBS2,MPDZ,PROM1,PTBP2,DIS3L,SLC4A8,IGDCC3,KIAA0586,JAKMIP2,KLHL5,EMX2,EPB41,NSRP1,ACSL4,FDFT1,FGF12,SMC2,C15orf41,PCLO,CIT,LSS,NFIX,OPA1,DIRAS2,ELOVL2,CLIP1,CASC3,KIF21A,SPATA7,BDP1,SOX11,SYNE2,BHLHB9,ZKSCAN5,USP1,HNRNPA3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.59E-05 1.26E-01 1.47E-04 1.33E-03 31 139 "ADGRF5,ARRB1,CA8,CD86,CD38,MS4A7,LY86,CSF1R,CYBB,EPHB1,IGSF6,SIRPB1,F8,FCGR1A,FYB1,GGTA1P,LYVE1,NCKAP1L,TM6SF1,MSR1,NCF2,PTPRB,SGK1,ST8SIA1,SLA,ARHGAP9,TEK,TLR4,NPL,FAM13C,SOCS4" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1 Gudmap RNAseq 2.63E-05 1.28E-01 1.49E-04 1.35E-03 163 1165 "ABCF1,AXIN2,PLEKHH1,MYH7B,UPRT,VAT1L,BCAS1,CPNE5,ARHGDIG,DOCK11,BACH1,ADGRB2,BCHE,BLM,ZNF599,PROM1,FUBP1,WASF1,CA12,PTBP2,CCNT1,CDH2,FAM19A5,C4orf33,QKI,CNTFR,BAG4,NECTIN3,SLC35F1,FAM171B,CRMP1,FAM169A,PPP1R16B,CTH,GREB1,KATNAL2,RASSF2,DDX46,SHANK1,CASP8AP2,E2F5,AASDH,EIF5,PLEKHA1,CERCAM,CD320,REEP2,TBC1D16,CORO2B,CEP78,PRMT5,POLR1B,SPSB4,FGF12,BAIAP2,FHL1,ZMYND15,NOP56,COQ5,CINP,SMC2,FAM49B,USP21,PRELID3A,MTHFD2,GATM,RUNDC3A,TCERG1,DBF4,GLI2,TOX3,CBX1,KIAA1958,KDM2B,LPAR4,STMN2,PSIP1,FAM222A,HSF2,SHISAL1,NKD1,LRRCC1,SLC35G1,KIF2A,IPO5,KTN1,CAMK2N2,HECTD2,MAT2A,AQP11,ADAM11,AFF1,MN1,SAMD5,MYCN,CNOT4,NOVA2,PCBP3,NTRK3,PDCD2,ENPP2,FAM98B,OLA1,NLGN3,SEMA5B,PKM,SLC25A23,PSAT1,POLR2F,PPP1R1A,PRODH,RELN,LAMA1,SPDL1,PTN,PTPN13,EML5,CCDC40,ERI2,FIGN,NUDT11,RPL15,SCN8A,TNFRSF19,ZFP2,PPM1E,FHOD3,CCDC92,ANKRD6,NUBPL,PKNOX2,SOX11,ZNF423,ZC3H13,RBM26,PBLD,LARP4,MTCL1,MCF2L,WSCD1,SIRT1,C18orf54,ITGB3BP,BEX4,NPL,TST,USP1,XPO1,CFAP298,KCNT2,ZFP41,ZNF184,SMARCAD1,MEIS3,SLC38A1,TUBA1A,WNK3,AMN1,FZD3,MRPL47,AAAS,NETO2,SPATA13" Coexpression Atlas PCBC_DE_blastocyst_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_1000 PCBC 2.72E-05 1.32E-01 1.54E-04 1.39E-03 142 991 "KCNH8,ACHE,TMEM132B,GALNT13,ADD2,PTCHD1,SEMA6A,ARHGAP20,PCDH10,UNC79,PDZD4,DPP10,GAS7,APOC1,LGR5,RASL11B,RNF182,KIF1A,CARMIL3,CACNA1G,CALB1,CLDN10,DCLK1,FAM189A2,FAM19A5,IGLON5,COL9A1,GAL3ST1,IPCEF1,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,KCTD8,BRINP1,AIF1L,LYPD1,PLPPR4,HS3ST2,DPP6,FAM78B,ZNF391,PIPOX,ADGRV1,PPP1R1B,MEGF10,HRASLS5,GABRA3,CHL1,GABRB3,GAD1,GATM,FREM1,GNAL,GNG4,LPAR4,GPR37,TMEM121B,GRM2,GSTT2,HAS2,BACH2,IGFBPL1,C9orf129,HP,SHISA6,CELF5,NKD1,ZNF678,C2CD4C,KCND2,KCNF1,KCNJ5,KCNN1,GATD1,KIT,CAMK2N2,ZNF680,TCEAL5,NNAT,SEMA5B,JAKMIP1,PDZRN4,MAGEL2,FA2H,PPP2R2B,PPP2R2C,RASGEF1B,RELN,LAMA1,ELOVL2,STK32A,NKAIN1,ZNF844,SLC25A48,ACSS3,FAM184A,ZNF493,KHDRBS2,RET,PRIMA1,MAP6D1,HUNK,TMEM200C,INAVA,SOX3,SOX15,MCF2L2,NFASC,NUDT10,ADAMTS17,KLHL4,PCDHGA11,FAM189A1,ARHGAP9,PCDHA6,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,CSMD1,PIK3R5,TRPM2,CA14,RPRM,PDIA2,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,STOX2,GAL3ST3,WNK3,PLSCR4,CASC15,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_P2_testes_1000 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.74E-05 1.33E-01 1.54E-04 1.40E-03 121 819 "EMILIN3,TMCC3,ADD1,ADORA1,MTUS1,AGT,SORCS2,AK2,C1QTNF3,LTBP4,AMH,OGT,SEMA7A,NT5C3B,ARHGDIG,ARRB2,MARK4,BACH1,DST,ST3GAL5,DDR1,CALM1,CAMK2G,VXN,CBLN1,ARHGEF1,SCARB1,CLTB,CABP1,RBM39,RNF14,RASGEF1C,ARHGEF4,PUM1,ARHGAP32,SCRN1,DAPK3,SPOCK2,DBI,DBN1,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,RASL12,REEP2,TUBB3,SCML2,FGF13,FGFR1,CAMKK2,TPPP3,FYN,GATM,CSDC2,SPIN1,LPAR4,GPR37,GRB10,IL6ST,ITPKA,KIF2A,TTYH2,LAMA2,SMAD1,CHIC1,MEF2C,MOV10,NRBP2,MYO7A,NEXMIF,NFIX,NNAT,SEMA5B,PLEC,FXYD1,EXOSC10,PPP2R5E,PRKACB,ELOVL2,PTPRE,MEG3,S100B,PRCD,SUPT20H,ARX,SMARCA4,SNRPN,SPP1,SULF2,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,USP22,OBSL1,PUM2,THRA,TMPO,TNS1,NR2C2,TST,SGK3,UBTF,UCHL1,USP1,ZFAND5,STOX2,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas gudmap_kidney_adult_GlomCapSys_Tie2_1000 kidney_adult_GlomCapSys_Tie2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.80E-05 1.36E-01 1.58E-04 1.43E-03 125 852 "ADCY6,USP31,MTUS1,HECW2,TAOK1,ADGRF5,SEMA6A,SEMA7A,PI16,ARNTL,ARRB1,NUMB,ADAM15,GPR146,CFLAR,THSD7A,CAST,LDB2,CD38,UBE2L6,CLTB,TMEM184B,CABP1,CLOCK,C2CD2,ANKRD44,CSF1,LRRC3B,ARHGEF10,CST3,PPP1R16B,KIAA0040,MYADM,PITPNC1,ECM2,EBF1,EDN1,EDNRB,KLHL5,FRY,PCOLCE2,CALCRL,RASGRP2,CEP85L,F8,CORO2B,DLC1,ST3GAL6,CHST15,FGFR3,POLK,FLT1,UFM1,PDLIM5,TRIM16,ERAP1,INPP5K,PCDH17,GGTA1P,GLUL,FERMT2,STMN2,ELOVL5,GABARAPL2,ICA1,IFI16,SCIN,ITPKB,KCNJ5,LIFR,LMO2,MAPT,MBNL1,MEF2C,MEIS2,KITLG,MSR1,MX1,LAYN,NFE2L2,NFIX,P2RX7,P2RY1,SERPINI1,CCSER2,PLTP,PMP22,DRAM2,MINDY2,MAPK3,SNRK,PTPRB,PTPRG,RIPOR1,C1orf54,ZDHHC14,RDX,LRRK2,SCN7A,SGK1,FAM81A,PREX2,LIMS2,CPEB4,LIMCH1,LMBRD1,ERC1,ARHGAP26,DBNDD2,SPTAN1,THSD1,RGL1,PLCB1,SYPL1,ANKRD12,SYNE1,TNS2,TEK,C18orf54,SLC44A1,TLR4,TNS1,LYPD6,PLSCR4,MSRB3" Coexpression Atlas GSM538282_500 "Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3" "Immgen.org, GSE15907" 2.83E-05 1.37E-01 1.59E-04 1.44E-03 71 425 "TMCC3,ADRB2,BEND6,ABCD2,CPNE5,CASK,ATP6V0A1,NRP2,DST,CA4,CH25H,MTMR7,FAM189A2,LY86,CDC42BPB,GDA,ABCG1,CSF1R,PNPLA8,CYBB,DOCK4,MYADM,ARHGAP24,DAPK1,ARRDC4,ABCC5,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,PCYOX1,FLT1,HVCN1,AK8,TPPP3,GCNT2,GGTA1P,GLUL,PRUNE2,KCNN3,TTYH2,LAMP2,PIK3AP1,GPR155,MATN2,MITF,MYO6,P2RY13,NCF2,NUCB2,SNX10,PLTP,LRP12,PILRA,RASGEF1B,SGK1,CCDC88A,SPP1,NXT2,SULF2,SYNE2,ADGRL3,DMXL2,CYB561A3,TLR4,TNS1,AGMO,PLD4,NLRP3" Coexpression Atlas gudmap_kidney_adult_RenalCapsule_1000 kidney_adult_RenalCapsule_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.98E-05 1.45E-01 1.67E-04 1.51E-03 116 780 "ESYT2,MTUS1,C1QTNF3,ALCAM,SRPX,LTBP4,AMPD3,PI16,UPRT,DDO,ARNTL,TMEM108,SLC4A4,DOCK11,ADAM23,BCHE,CFLAR,RAB29,MYRF,IL33,CACNA1A,CAST,CLDN10,SLC16A4,MS4A7,CLTB,LY86,ARHGEF6,ABI3BP,CLOCK,ANKRD44,CSF1,CSF1R,CST3,PLXNA4,CYBB,BOC,SPOCK2,CHRDL1,CDON,ECM2,EBF1,SEMA3D,TMTC1,EGFR,IRAK4,PCOLCE2,ELN,RCAN2,DENND4A,MRVI1,ABCA8,PTK2B,ST3GAL6,FCGRT,FGF1,FHL1,PDLIM5,FYB1,GALNT15,ERAP1,GCNT2,RAB30,LILRB4,GSN,GUCY1A1,IRAK3,NCKAP1L,HNMT,IFI16,IGF1,IL6ST,LAMA2,MATN2,MBNL1,TM6SF1,MEIS1,MSR1,NBL1,NFIX,NPR2,NTRK2,NUCB2,PCDH9,PDE3A,ABCB1,PIK3R1,FXYD1,PLTP,PMP22,MINDY2,NKAIN4,PKIA,PTPN13,RNASEL,ARMH4,MRAS,CNKSR2,KANK1,SULF2,SYNE2,COBL,CYB561A3,ZFPM2,SLC44A1,TLR4,LRRC8A,TNS1,FLRT2,PLEKHH2,VLDLR,KCNT2,AGMO,KCNAB1,PLD4,PLSCR4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.98E-05 1.45E-01 1.67E-04 1.51E-03 19 67 "METAP1D,ADCY8,AMPH,CACNB4,RBM39,CRYM,DYNC1I1,TMEM35A,EYA1,FGF1,GABRB3,FAM107A,HAS2,FRMD3,ROBO2,SALL1,ZFP2,SLC12A2,TPM2" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K4 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.98E-05 1.45E-01 1.67E-04 1.51E-03 19 67 "LTBP4,GPRASP2,BMPR1B,SRSF11,LHX2,EMX2,ACSS1,GATM,PPARGC1A,RABL2A,NCAM2,NELL2,PCDH9,RTN1,SALL1,MAST1,FAM189A1,NR2E1,SENP7" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000_k4 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.99E-05 1.45E-01 1.67E-04 1.51E-03 48 256 "PCDH19,ARHGAP20,PTCH2,ADGRB3,IL33,RUNX1T1,LDB2,ZNF445,COL4A5,CSF1R,ZC3H11A,CDON,EDNRA,SEMA3D,APH1A,ETV1,TMEM132C,FCGRT,NBEA,SMC2,TNRC6A,PARD3B,RASSF8,HAS2,MATN2,MEIS1,MEIS2,MMP16,SAMD5,PCDH9,PCSK5,NALCN,PIK3R1,PLCL1,PTN,C1orf54,RNASEL,MEG3,TET1,ARFGAP1,PRRC2C,PCDHB9,HIF3A,TRPS1,SSBP2,FLRT2,VLDLR,ZNF142" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274 Gudmap Mouse MOE430.2 2.99E-05 1.45E-01 1.67E-04 1.51E-03 48 256 "OSBPL8,FAM135A,USP37,TMEFF1,CACNA1B,PTBP2,CH25H,RCBTB2,COL9A1,LRIG1,CSNK1G3,PDE4DIP,APPL1,PITPNC1,EBF1,EDNRA,SEMA3D,CALCRL,ETV1,FGF13,MEX3B,SYNCRIP,GPD2,MAP4K5,RASSF8,MIER3,LRRCC1,MAP2,NEFM,NALCN,GRAMD1C,KLHL11,RPS20,FNIP1,KIF21A,WDR37,SLC12A2,CMTR2,FAM126B,ADGRL3,TCF4,TRIM2,ERCC6L2,FLRT2,ZNF711,PHTF2,ZDHHC20,SOCS4" Coexpression Atlas GSM605859_500 "Myeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 3.06E-05 1.48E-01 1.71E-04 1.55E-03 71 426 "TMCC3,ALCAM,ABCD2,FGD2,GAS7,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,CD38,SOCS6,B4GALT6,LY86,GDA,CSF1R,CSF2RA,GALNT9,CST3,PLXNA4,CYBB,MYADM,DGKG,DAPK1,DBI,ARRDC4,FAM78B,EDNRB,IGSF6,TLR7,SIRPB1,FCGR3A,FCGRT,OLFM1,FGFR1,AK8,TPPP3,GATM,SLC2A6,IRAK3,LRRC25,IL6R,ITGAM,LAMP2,LIFR,MITF,MSR1,NCF2,NUCB2,P2RY1,PFKFB4,PLTP,PMP22,PILRA,DRAM2,PID1,C1orf54,MRAS,CCDC88A,SLC11A1,ELMO2,SULF2,KIAA0930,TIAM1,TLR4,TRPS1,TUBB2A,LAT2,AGMO,EVI5,PLD4" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k4_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.20E-05 1.55E-01 1.78E-04 1.62E-03 16 51 "SEMA7A,MARK4,PPP1R16B,MBNL2,FAM198B,FYN,GATM,ITPKB,RPS6KA2,FAM102A,SPP1,ARHGAP26,TACC1,DCBLD1,ADAMTS9,NHSL1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k2 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.20E-05 1.55E-01 1.78E-04 1.62E-03 16 51 "CACNA2D1,SYNCRIP,PDLIM5,GALC,RAPGEF6,ZHX1,LIMS1,NCOA7,CHIC1,ENPP2,RYR3,FAM126B,ZHX3,ERCC6L2,TRPS1,VLDLR" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k1_1000 dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.22E-05 1.56E-01 1.79E-04 1.62E-03 38 187 "SPARCL1,SEMA6A,LCORL,ARRB1,DOCK11,BACH1,SPAG9,LDB2,CNN3,ZNF521,DBN1,ARMCX4,EDIL3,YAF2,MBNL2,STX2,DLC1,CHST15,UFM1,FYN,ZDHHC15,IGF1,ITPKB,MEST,MYO6,PALM,PDE4D,GNG2,ROBO1,SEMA6D,PEG10,ZNF423,RGL1,ARHGEF9,TCF4,ZEB1,ZNF711,STOX2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.41E-05 1.65E-01 1.90E-04 1.72E-03 45 236 "ADCY8,ALCAM,BCHE,CBLN1,FOXN3,CLCN3,LRRC3B,HDAC9,MYADM,WDR20,RRAGB,REEP2,CEP78,FGF11,SYT3,CSDC2,TOX3,HMGCL,TCEAL6,SHISAL1,ZIC5,CDH20,KHK,MATN2,PRTG,NLGN3,ZFYVE21,MAGEL2,NKAIN4,RELN,PTPN13,CCDC40,TSPY26P,STK32B,EMID1,SALL1,MAPK12,SLC4A3,PKNOX2,SNRPN,PDZRN3,ADAMTS17,WSCD1,ZIC2,SLC38A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k1 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.42E-05 1.66E-01 1.90E-04 1.72E-03 14 41 "CHGB,COL9A1,COL9A3,EBF1,GFRA2,STMN2,NEGR1,INSM1,MAP4,CLDN11,MAPK10,PRPH,RGS4,SNAP25" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.52E-05 1.71E-01 1.95E-04 1.77E-03 24 97 "KLHL13,LGR5,CDC14B,PPP4R4,IGDCC4,DCLK1,PLXNA4,DOCK4,DRP2,EMX2,MTSS1L,AFF2,TRAF3IP2,KCND2,KLHL23,REV3L,RASA3,ST8SIA1,SLC4A3,ST5,ADGRL3,OBSL1,ZFPM2,WNK3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 3.54E-05 1.72E-01 1.96E-04 1.78E-03 62 360 "OSBPL1A,TBC1D14,KIAA1324,GAS7,CPNE5,ARRB2,ATP1A3,RIPK1,ZNF599,ARHGEF1,FAM149A,SUMF2,CREM,CRY2,OSBPL3,PITPNC1,EDNRA,HIPK3,NCALD,CDKL3,CORO2B,ST3GAL6,PPP1R1B,POLK,APOPT1,UFM1,TPK1,DLL3,TMEM8B,ADAMTS6,GUCY1B1,SMAP1,IGF1,KCNJ5,KIT,HECTD2,MBNL1,NFE2L2,SMIM11A,ETFRF1,PCSK5,ENPP2,PCDH18,DIRAS2,MASP1,CYBC1,GDPD2,TMEM260,STRC,REV3L,FAM161B,KCNIP3,SEMA6D,SH3BP2,MYO18A,MBD5,SPATA7,ERBIN,TNS1,TSC1,EVI5,PRRT4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K1 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 3.61E-05 1.75E-01 2.00E-04 1.81E-03 49 265 "EMILIN3,SEMA6A,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,PCYT1B,ABI3BP,ANKRD44,SNCAIP,EBF1,ELN,LRRC17,FCGRT,SYT3,TRIM16,NSG1,TVP23A,ZNF276,RASSF8,HLF,SYNPO,CREG2,SRSF12,MSR1,TCEAL5,NFIX,NPY,CNTN3,PDE4D,ACSS3,IQSEC3,BEND5,ZFHX4,LRRK2,DGLUCY,SH3GL3,SLC8A1,PDZRN3,ARHGAP26,PLCB1,SATB2,PHF24,TRPS1,TSPAN11" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_500 dev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.93E-05 1.91E-01 2.17E-04 1.97E-03 69 414 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,SEMA7A,MAP4K3,APBB2,SHROOM2,DOCK11,NRP2,ARHGEF7,CBLN1,LDB2,SCARB1,CD38,ABCG2,CRMP1,HAPLN1,PPP1R16B,DOCK4,RASSF2,GIT2,ELMO1,EBF1,EDNRB,PLEKHA1,CALCRL,RASGRP2,FAM198B,CORO2B,DLC1,FLT1,PDLIM5,FYB1,FYN,PCDH17,GGTA1P,LPAR4,GRIA2,MAP4K5,ICA1,ITPKB,KIT,LMO2,TM6SF1,MEF2C,SNRK,PTPRB,TMEM255A,C1orf54,ROBO1,SEMA6D,RASA3,PREX2,LIMCH1,UNC5B,PEG10,THSD1,KLHL4,TCF4,TEK,HEY1,DCBLD1,VSNL1,WIPF1,ZNF711,NAV3,FAM13C" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_500 dev gonad_e11.5_M_ReproVasc_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.93E-05 1.91E-01 2.17E-04 1.97E-03 69 414 "HECW2,ADGRF5,NRP2,ARHGEF7,CA8,LDB2,CD38,ABCG2,LY86,CNN3,ZNF521,CRMP1,HAPLN1,CSF1R,RASSF2,PITPNC1,ELMO1,FAM107B,EBF1,EDN1,EDNRB,YAF2,CALCRL,RASGRP2,DENND4A,CORO2B,FLT1,TMEM107,UFM1,PDLIM5,FYB1,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,LPAR4,STMN2,MAP4K5,NCKAP1L,ZDHHC15,ICA1,IGF1,KIT,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,SNRK,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,PREX2,BTBD3,LIMCH1,PEG10,THSD1,KLHL4,TEK,C18orf54,TLR4,FLRT2,WIPF1,ZNF711,NAV3" Coexpression Atlas GSM777019_500 "B cells, B.Fo.LN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-2" "Immgen.org, GSE15907" 3.96E-05 1.92E-01 2.19E-04 1.98E-03 59 339 "ADRB2,ZNF608,TXNDC16,BIN1,FGD2,ATP6V0A1,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,CSNK1G3,KIAA0040,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,ELMSAN1,SLC12A6,EBF1,SNX29,FRY,SRPK3,TLR7,HVCN1,TRAF3IP2,RAB30,DCLK2,IRAK3,BACH2,IRF8,IL12A,FAM69A,LMO2,PIK3AP1,MEF2C,NCF2,PPP3CC,RASGEF1B,MARCH1,BEND5,LRRK2,SH3BP2,ST6GAL1,SLC4A3,LMBRD1,ARHGAP26,STAC2,SYPL1,MGRN1,CYB561A3,TLR4,C9orf85,LAT2,SIGLEC10,PLD4" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0 facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0 Gudmap RNAseq 4.00E-05 1.94E-01 2.20E-04 2.00E-03 152 1082 "PLEKHH1,KIAA1211,KLHL13,HACE1,KIAA1324,PDZD4,AMPH,LRCH2,MYH7B,EPB41L5,VAT1L,BCAS1,TMEFF1,ARHGDIG,KIF1A,BARD1,BCHE,ZNF599,PROM1,WASF1,MYRF,CA12,THSD7A,PTBP2,MTMR7,CDH2,LRWD1,CACNA2D2,CLCN3,FAM19A5,C4orf33,CNTFR,BAG4,NECTIN3,SLC35F1,FAM171B,CRMP1,CNTNAP2,FAM169A,CTH,GREB1,TMEM170A,AIF1L,DMD,E2F5,SEZ6L2,TSPAN5,PLEKHA1,ENO2,EXTL2,REEP2,TBC1D16,CEP78,SPSB4,FGF13,FHL1,ZMYND15,NOP56,SYT3,CINP,FAM49B,PRELID3A,FUT9,RUNDC3A,DBF4,TOX3,CBX1,GPD2,LPAR4,STMN2,RNF165,PSIP1,FRMD5,HLF,CFAP126,HSF2,LRRCC1,SLC35G1,IPO5,KTN1,CAMK2N2,MAT2A,AQP11,MEST,MIA2,MSI1,MYCN,NOVA2,PDE1B,FAM98B,OLA1,SNX10,PKM,PSAT1,POLR2F,FSD1,PPP1R1A,PKIA,PRKCB,MAPK4,RELN,GDPD2,ELOVL2,SPDL1,ZIK1,PTPN13,EML5,NKAIN1,CEP97,CCDC40,FAM184A,FIGN,NUDT11,RPL15,RTN1,SALL1,MAPK12,ZFP2,HSPA4L,KIF21A,PPM1E,FHOD3,CCDC92,PPP4R3A,PKNOX2,KDM4B,SOX11,PBLD,ZC4H2,MTCL1,CUX2,C18orf54,ITGB3BP,AKTIP,RELL2,ACTR6,BEX4,RGMB,UBE3A,XPO1,KCNT2,ZFP41,TMEM237,SMARCAD1,SLC38A1,STOX2,WNK3,AMN1,FZD3,PHTF2,NETO2,SPATA13" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_1000 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.02E-05 1.95E-01 2.21E-04 2.01E-03 113 761 "ACADM,ADORA1,AMPH,EPB41L5,USP37,LGR5,ASPA,DYNLL1,ATP1A1,BMP7,CA4,CA8,CA12,CALB1,CLDN10,RBM39,OSBPL3,PPP1R16B,KIAA0040,GREB1,ARHGAP24,SPOCK2,DDX46,GUCD1,FAM107B,DUSP9,EDNRB,MBNL2,EIF5,EMX2,HSD17B14,PIPOX,ST3GAL6,FGF1,FGFR1,FGFR3,FHL1,FOXO3,SEMA4D,ATP13A4,SMC2,PDLIM5,KHDRBS3,CELF1,CGREF1,FUT9,MTHFD2,ACSS1,IGSF5,ALDH1L1,PPARGC1A,CBX1,GPD1,CIT,AP4S1,GUCY1A1,GUCY1B1,IDH3A,SCIN,CLEC18A,AQP11,TM6SF1,MEF2C,MITF,MYO6,NPY,OXTR,PALM,CYTL1,RETREG1,SCHIP1,IRX1,PPP5C,LAMA1,PTH1R,ELOVL2,PTPN13,PTPRG,PTPRO,ZDHHC14,RDX,RET,EMID1,SGK1,KIF21A,SHMT2,FHOD3,SMARCA4,LIMCH1,DDN,LARP4,APOM,RGL1,PRRC2C,SYPL1,COBL,CAMTA1,SATB2,TRIM2,HEY1,CBX5,NPL,AMACR,TST,SGK3,UGT8,ZNF24,SPIRE1,EVI5,STOX2,TMEM178A,VPS35L,SPATA13" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.10E-05 1.99E-01 2.25E-04 2.04E-03 8 15 "CNTFR,CLIP3,GFRA2,TAGLN3,SLC10A4,PRPH,SST,UCHL1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.13E-05 2.00E-01 2.27E-04 2.06E-03 34 162 "ARHGAP20,MYRF,CALB1,CBLN1,CNTFR,HAPLN1,VCAN,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,FLNC,FREM1,GHR,GPR37,GUCY1A1,GUCY1B1,KCND2,KLHL23,MATN2,MEIS1,NEFM,PCDH18,PTN,TMEM255A,ROBO2,UHRF1BP1L,ADGRL3,KLHL4,ZFPM2,ACTR6,WNK3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.23E-05 2.05E-01 2.32E-04 2.10E-03 28 123 "SPARCL1,ALCAM,ARHGAP20,CACNA1G,SLIT2,VCAN,BOC,DNM1,EDNRA,EGFR,LRRC17,FLNC,GFRA2,FREM1,GUCY1A1,GUCY1B1,NKD1,MEIS1,PCDH9,PIK3R1,FXYD1,PCDH18,LAMA1,PTN,TMEM255A,MEG3,FLRT2,VSNL1" Coexpression Atlas facebase_RNAseq_e10.5_MandArch_2500_K1 facebase_RNAseq_e10.5_MandArch_2500_K1 Gudmap RNAseq 4.25E-05 2.07E-01 2.33E-04 2.11E-03 171 1243 "ABCF1,CEP126,LRCH2,MYH7B,APC,DYNLL1,SLC4A4,SEC11C,BLM,ZNF599,PROM1,BMPR1B,NAE1,CACNA1G,CA12,PTBP2,RUNX1T1,CCNH,USP2,C1orf52,LRBA,SEPT7,KCNAB3,C4orf33,TBPL1,AHCTF1,HAPLN1,GDA,CLIP3,IPCEF1,VCAN,FAM169A,DZIP3,PHF14,PNPLA8,GREB1,LIN54,PITPNC1,GSDME,DDX46,MTX3,USP3,CASP8AP2,E2F5,EDN3,EDNRA,OPTN,EIF5,EIF1,EPB41,COQ7,LRRC17,CEP85L,CDKL3,ETV1,KATNAL1,EYA1,NSRP1,CORO2B,RACK1,TMEM164,UBE2E3,MEX3B,AFF2,NOP56,WDR83,SMC2,PRELID3A,MPP6,GFRA2,HPGDS,DBF4,CBX1,KCNMB4,LPAR4,CNTRL,PRDM5,CIT,PSIP1,ATOH8,MUM1,RASSF8,HSF2,SMAP1,LRRCC1,KCNJ16,KIF2A,KIT,LIG4,HECTD2,MEST,MID1,MXI1,LINC00672,TCEAL5,NBL1,CNOT4,SMIM11A,PDCD2,PDE4D,ENPP2,FAM98B,OLA1,RASGEF1B,CEP41,GDPD2,CNTLN,SPDL1,ZIK1,NKAIN1,RAD17,CCDC40,BEND5,RBBP8,RDX,FIGN,SETD5,RPS20,RTN1,CCDC112,ZFP2,SH3GL3,CHD9,FHOD3,ST6GAL1,CNKSR2,DZIP1,DHX30,PKNOX2,ARHGEF40,CCDC88A,ZNF334,RBM34,RBM26,SS18,ERBIN,DNAJC9,TAF9,TAL1,SATB2,CUX2,ZEB1,NSD1,ITGB3BP,ACTR6,ASXL3,TMPO,R3HDM1,PIK3R5,C9orf85,METTL3,PDSS1,STXBP4,TRPS1,UBE3A,USP1,ZNF711,ZNF23,ZFP41,AGMO,ZNF184,EML6,SMARCAD1,EMSY,EVI5,PPP1R3F,MRPL47,SMIM8,FXR1,NETO2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.30E-05 2.09E-01 2.35E-04 2.13E-03 18 63 "RUNX1T1,SEPT7,NRXN3,CRMP1,TUBB3,TAOK3,STMN2,GRIA2,GRIK5,NEGR1,MAP2,NEXMIF,LRRN3,REV3L,MEG3,RTN1,CELF4,REEP1" Coexpression Atlas gudmap_RNAseq_e15.5_CollectIng Duct_2500_K0 gudmap_RNAseq_e15.5_CollectIng Duct_2500_K0 Gudmap RNAseq 4.34E-05 2.11E-01 2.37E-04 2.15E-03 118 803 "SYN3,AS3MT,ADORA1,AK2,DOC2A,LCORL,MYH7B,CPNE5,LGR5,PROM1,BMP7,BMPR1B,IL33,CA4,CALB1,HAP1,LRBA,CRLF1,CACNA2D2,CBARP,B4GALT6,CNOT8,SLIT2,MYL6B,QKI,FAM149A,COL9A3,CRYM,IPCEF1,CTH,GREB1,AIF1L,SEMA3D,EEF1D,TMEM35A,EMX2,COQ7,ERBB4,CD320,SH3YL1,ACSL4,SPSB4,FGF12,SEMA4D,POMT1,TPK1,RASL10A,CAMKK2,GFER,MMADHC,TOX3,KDM2B,FAM222A,PADI2,INSYN1,ACOT7,SHISAL1,INPP1,KCNJ16,KIT,L1CAM,STMN1,LYPLAL1,AQP11,ADAM11,COMMD5,BLOC1S2,MYO6,VWA2,NPY,PALM,PDE4A,PDE1B,KCTD15,SMIM7,PSAT1,POLR2F,PPP1R1A,MAPK4,PSMA6,LAMA1,ROGDI,RASGRF2,RET,MRPS18A,NUDT11,GLDN,SALL1,SCN8A,HES6,SH3GL3,FHOD3,ST6GAL1,FAM81A,KDM4B,SOX11,STAC2,STX1A,KANK1,TMEM150C,SYT5,CUX2,TMEM9,HEY1,DCBLD1,RPRM,CCDC136,VLDLR,VSNL1,CFAP298,SLC38A1,ADAMTS9,TMEM178A,CIAPIN1,ITM2C,PCBP4,WNK2,SPATA13" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.47E-05 2.17E-01 2.44E-04 2.21E-03 27 117 "TMCC3,JAZF1,CRLF1,ABI3BP,GSDME,SLC12A6,PLXNC1,EZH1,FOXO3,GATM,SHISA6,KIT,SYTL4,ABCB1,MAPK10,GDPD1,PCMTD2,SATB1,KIF16B,CPEB3,SLC14A1,CLSTN2,SYNE2,ANKRD12,CAMTA1,TBC1D15,NDRG4" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k5_500 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.48E-05 2.18E-01 2.45E-04 2.22E-03 15 47 "APLP1,CRMP1,GSDME,TUBB3,DLL3,LPAR4,STMN2,INSM1,MAPT,TAGLN3,NEFM,GNG2,TRIM2,ZIC1,PCBP4" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_200 DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.51E-05 2.19E-01 2.46E-04 2.23E-03 33 156 "LCORL,INSYN2B,BACH1,CALB1,RUNX1T1,SLIT2,RBM39,PUM1,DOCK4,TCAF1,EDNRA,EIF4G1,EMX2,MEX3B,SMC2,LPAR4,GPR37,INSM1,KCND2,CHIC1,MEIS2,KITLG,TMEM255A,TMLHE,ROBO2,MEG3,ARX,RBM26,KLHL4,CBX5,ACTR6,SSBP2,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_1000_k5 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.65E-05 2.26E-01 2.53E-04 2.30E-03 14 42 "AMPH,CRYM,SNAP91,EYA1,SCARA3,TVP23A,FAM107A,HAS2,TAGLN3,PRTG,CEP41,SALL1,ANKRD6,NETO2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 4.71E-05 2.29E-01 2.56E-04 2.32E-03 34 163 "PTCHD1,ATP2B2,CAMK2A,SLIT2,IQCK,COL4A5,DTNA,CLVS1,SPSB4,AFF2,DLL3,NTNG2,RNFT2,TOX2,BACH2,IGFBPL1,CELF5,ZIC5,KCNH2,LINC00672,SLC11A2,NRCAM,PGAM2,MAPK10,RAD51D,GAL3ST4,CCDC112,TMCC1,RHBDL3,ASTN2,TRIM2,FRYL,ZIC1,SENP7" Coexpression Atlas GSM854294_500 "Myeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 4.72E-05 2.29E-01 2.56E-04 2.32E-03 70 424 "TMCC3,ALCAM,ABCD2,GAS7,CASK,ATP1A3,ADAM15,ST3GAL5,CD86,SOCS6,CHN2,B4GALT6,LY86,GDA,CSF1R,CSF2RA,GALNT9,CST3,PLXNA4,CYBB,HDAC9,MYADM,DAPK1,DBI,DMPK,FAM78B,EDNRB,IGSF6,ETV1,SIRPB1,F5,FCGR3A,FCGRT,OLFM1,FGFR1,FOLR2,AK8,TPPP3,GATM,GFRA2,SLC2A6,IRAK3,LRRC25,ITGAM,LAMP2,LIFR,MITF,MSR1,NCF2,NUCB2,P2RY1,PLTP,PMP22,PILRA,DRAM2,PID1,C1orf54,MRAS,CCDC88A,SLC11A1,PLCB1,KIAA0930,TIAM1,TLR4,TRPS1,TUBB2A,LAT2,AGMO,EVI5,PLD4" Coexpression Atlas PCBC_ratio_MESO-30 fibroblast_vs_MESO-30 blastocyst_cfr-2X-p05 MESO-30 fibroblast_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.81E-05 2.34E-01 2.60E-04 2.36E-03 82 517 "ACTN1,TMCC3,AXIN2,MTUS1,SRPX,MARCH4,PCDH10,LGR5,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,PDE4DIP,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,SIRPB1,PRKAG2,FHL1,PDLIM5,CSPG5,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,SYNPO,IGF1,NKD1,ITGA7,KCNK3,LAMA2,HECTD2,LAYN,BEX5,NDP,ALDH1L2,PGAM2,DUSP26,PMP22,EPDR1,CNNM2,PTCH1,KCTD17,RNASE1,SUGCT,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,KIF13A,TEX2,UNC5B,CLSTN2,KLHL4,ZFPM2,ZMAT3,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,MSRB3,FRMD6,SRGAP2B" Coexpression Atlas PCBC_ratio_MESO-30_from-OSKM - NLT_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-reprogram_OSKM - NLT_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.81E-05 2.34E-01 2.60E-04 2.36E-03 82 517 "ACTN1,TMCC3,AXIN2,MTUS1,SRPX,MARCH4,PCDH10,LGR5,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,PDE4DIP,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,SIRPB1,PRKAG2,FHL1,PDLIM5,CSPG5,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,SYNPO,IGF1,NKD1,ITGA7,KCNK3,LAMA2,HECTD2,LAYN,BEX5,NDP,ALDH1L2,PGAM2,DUSP26,PMP22,EPDR1,CNNM2,PTCH1,KCTD17,RNASE1,SUGCT,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,KIF13A,TEX2,UNC5B,CLSTN2,KLHL4,ZFPM2,ZMAT3,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,MSRB3,FRMD6,SRGAP2B" Coexpression Atlas PCBC_ratio_MESO-30_from-plasmid_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-method_plasmid_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.81E-05 2.34E-01 2.60E-04 2.36E-03 82 517 "ACTN1,TMCC3,AXIN2,MTUS1,SRPX,MARCH4,PCDH10,LGR5,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,PDE4DIP,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,SIRPB1,PRKAG2,FHL1,PDLIM5,CSPG5,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,SYNPO,IGF1,NKD1,ITGA7,KCNK3,LAMA2,HECTD2,LAYN,BEX5,NDP,ALDH1L2,PGAM2,DUSP26,PMP22,EPDR1,CNNM2,PTCH1,KCTD17,RNASE1,SUGCT,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,KIF13A,TEX2,UNC5B,CLSTN2,KLHL4,ZFPM2,ZMAT3,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,MSRB3,FRMD6,SRGAP2B" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.88E-05 2.37E-01 2.64E-04 2.39E-03 35 170 "SEMA7A,APOC1,CDC14B,ARHGDIG,RGS11,DST,ST3GAL5,RGN,GPRASP1,DBI,CPEB2,DTNB,PLXNC1,CERCAM,AFF2,CAMKK2,ZMAT1,GPR37,SHISA6,SYTL4,NCOA7,MOV10,ETFRF1,PEX2,SH3TC2,RPS6KA2,ATXN2,MRAS,FRMPD1,ST8SIA1,TSPYL2,OBSL1,TST,ADAMTS9,WNK3" Coexpression Atlas GSM791122_500 "Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2" "Immgen.org, GSE15907" 5.20E-05 2.52E-01 2.81E-04 2.54E-03 68 410 "FMNL2,ZNF608,OSBPL1A,CDC42BPA,BLM,PRC1,B4GALT6,ABCG2,CNN3,ZNF521,CNRIP1,DZIP3,GPRASP1,ARHGAP32,ARMCX4,EBF1,EBI3,PLXNC1,CALCRL,EYA1,ARMCX1,NBEA,SMC2,GATM,GCNT2,SESN1,GRB10,PRDM5,GSTM5,GUCY1A1,IRAK3,HLF,ICA1,LRRCC1,IL12A,KLHL23,KIT,STMN1,LMO2,LYPLAL1,MEF2C,MEIS1,MEST,MYCN,NME4,OCRL,RNASEL,BTBD3,SLC12A2,TET1,PEG10,SAMSN1,THSD1,CEP68,SYNE2,KLHL4,HIF3A,TEK,CBX5,BHLHB9,NPL,STXBP4,SSBP2,TTC3,VIPR2,PHTF2,MSRB3,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.22E-05 2.53E-01 2.82E-04 2.55E-03 38 191 "KDM5D,AMH,SEMA7A,GAS7,CADPS,ATP1A1,ALDH7A1,CACNA2D2,MAGED1,SCRN1,DTNA,MRO,PLXNC1,ERBB4,FAM198B,PTK2B,FGF13,CAMKK2,IQGAP2,GATM,PPARGC1A,ADGRA3,GPR37,RASGEF1B,MASP1,ROBO1,PCMTD2,GLDN,MRAS,SPP1,TSPYL2,SYNE2,THRA,TIAM1,SGK3,CLDND1,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.23E-05 2.54E-01 2.82E-04 2.56E-03 27 118 "PCDH10,SYT13,INSYN2B,CH25H,RUNX1T1,CBLN1,DCLK1,CRLF1,PITPNC1,TIAM2,DLX1,EDNRA,TMEM132C,SYNCRIP,GNG4,ZFHX4,SALL1,TNFRSF19,LIMCH1,SOX11,TCF4,ERCC6L2,KAT6B,TRPS1,FLRT2,KCNAB1,FRMD6" Coexpression Atlas gudmap_RNAseq_e15.5_Mesangium_2500 gudmap_RNAseq_e15.5_Mesangium_2500 Gudmap RNAseq 5.26E-05 2.55E-01 2.83E-04 2.57E-03 243 1867 "ABR,EMILIN3,AK2,C1QTNF1,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PDZD4,AMPH,PI16,MYH7B,EPB41L5,PHYHD1,IGDCC4,MARCH3,DYNLL1,CHID1,SLC4A4,ALDH7A1,KIF1A,ADGRB2,MYRF,IL33,CA4,CACNA2D1,CALB1,SLC25A14,ARHGEF25,LDB2,ENTPD2,LONRF2,DLGAP1,CHGB,NRXN3,PPT2,MYL6B,FAM189A2,CNTFR,COL9A1,MAGED1,AKAP12,CRYM,SNCAIP,CST3,PLCXD3,BOC,MYADM,ARHGAP24,SPOCK2,BRINP1,AIF1L,HEPH,SNAP91,ARRDC4,FIS1,HEYL,EEF1D,TMTC1,EGFR,RASA4,ING4,ELN,TMEM35A,CALCRL,EMX2,ENO2,COQ7,LRRC17,RASGRP2,ERBB4,NCALD,SPEG,RASL12,ADGRV1,EYA1,CD320,MRVI1,HSPA12B,REEP2,DLC1,RACK1,FCGRT,OLFM1,SCARA3,ATP5PD,PCYOX1,VTI1B,FLNC,SLC37A3,POMT1,HVCN1,RASL10A,NSG1,TPPP3,TVP23A,SDCBP2,IGSF5,GFER,MMADHC,FREM1,CSDC2,GGTA1P,GGT5,DHRS4,NTNG2,LOXL3,FERMT2,CACFD1,LINGO1,GUCY1A1,GUCY1B1,ATOH8,FAM222A,IRAK3,RASSF8,HAS2,INSYN1,ACOT7,HMGCL,NEGR1,SHISAL1,IGF1,NKD1,IL6ST,KCNH2,KCNK3,GATD1,KHK,TTYH2,LAMA2,CAMK2N2,STMN1,LSAMP,MATN2,MEIS1,MGAT3,MITF,MMP17,MOV10,COMMD5,BLOC1S2,THYN1,TAGLN3,MXI1,NEFM,NFIX,NNAT,NME4,NPY,NTRK2,NTRK3,CLDN11,PALM,PCSK5,PDE3A,ENPP2,PLCB2,FXYD1,PCDH18,SMIM7,PLTP,SDK2,FA2H,SH3KBP1,POLR2F,PPP1R1A,NKAIN4,CEP41,MASP1,RELN,PSMA6,PTH1R,PTX3,ZSCAN2,TMEM231,C1orf54,FAM184A,SUSD4,ROGDI,RGS4,MRPS18A,RNH1,LGI2,ROBO2,GLDN,EMID1,SALL1,SARS,SCP2,PEAR1,SEC14L1,SH3BGR,SH3GL3,SHMT2,ST8SIA1,SLC8A1,ARFGAP1,SMARCD3,KDM4B,PDZD2,LHPP,CLSTN2,ITPRID2,RGL1,STAC2,STX1A,SYP,PJA1,TAF9,PDLIM2,SIN3B,CUX2,TNS2,ZFPM2,GALNT17,THRA,ENHO,TMEM9,HEY1,TK2,TPM2,IL34,UBC,UBE2H,UCHL1,FLRT2,PLEKHH2,MTCH1,VLDLR,CLIP2,CLDND1,KCNT2,POLR3H,ZNF189,ADAMTS9,TMEM178A,CIAPIN1,PPP1R3F,ITM2C,PCBP4,DPF3" Coexpression Atlas GSM854291_500 "Myeloid Cells, DC.8-4-11b-.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-3" "Immgen.org, GSE15907" 5.35E-05 2.60E-01 2.87E-04 2.61E-03 69 418 "FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,FGD2,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CD86,CDH2,UBE2L6,B4GALT6,ARHGAP22,STOML1,LY86,SLC4A8,ABCG1,CSF1,CSF1R,CST3,CYBB,MYADM,ARRDC4,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,FCGRT,ZMYND15,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,HSF2,IRF8,SCIN,INSM1,LIFR,ASPRV1,ADAM11,PFKFB3,CCSER2,PID1,ROGDI,RGS12,LRRK2,RTN1,SEMA6D,ARHGEF40,CCDC88A,SAMSN1,RGL1,SULF2,STXBP1,TMEM150C,ARC,ATMIN,PHF24,CYB561A3,SLC44A1,SYNPO2,ZBTB38,SPIRE1,ITM2C,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k4 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.36E-05 2.60E-01 2.88E-04 2.61E-03 34 164 "METAP1D,ADCY8,AMPH,SFMBT2,SEMA4G,CACNB4,FAM19A5,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,DYNC1I1,DTNA,TMEM35A,SPEG,EYA1,FGF1,SCARA3,GABRB3,FUT10,FAM107A,FRMD3,CNTN3,PPP1R1A,ROBO2,SUPT20H,HSPA4L,ANKRD6,SLC12A2,TCF4,TRIM2,TPM2,RICTOR" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_200 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.36E-05 2.60E-01 2.88E-04 2.61E-03 34 164 "GAS7,LGR5,CADPS,CALB1,RGN,SLC16A4,DCLK1,DOCK4,DAPK1,SCRN1,DRP2,MRO,EMX2,MTSS1L,NRN1,PTK2B,CAMKK2,GATM,PPARGC1A,GPR37,KLHL23,MATN2,KITLG,RBBP8,REV3L,ST8SIA1,SLC4A3,UHRF1BP1L,SPP1,ADGRL3,ZFPM2,ACTR6,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.42E-05 2.63E-01 2.90E-04 2.63E-03 16 53 "PCDH10,INSYN2B,DCLK1,SPOCK3,TMEM132C,SCML2,FOXF2,MEGF10,LPAR4,IFI16,MYH3,PCDH8,ZFHX4,CSRNP3,ADGRL3,SOCS4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.42E-05 2.63E-01 2.90E-04 2.63E-03 11 28 "FAM171B,ZNF804A,EYA1,TUBB3,GNAO1,SYTL4,NEFM,MAPK10,EML5,SNAP25,CUX2" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k5_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.77E-05 2.80E-01 3.08E-04 2.79E-03 30 138 "TAOK1,LCORL,LGR5,RNF182,RBM39,DZIP3,DOCK4,DTNB,EMX2,FAM198B,SCML2,TUBGCP4,TOX2,KCND2,KITLG,CNOT4,PDPK1,JAKMIP1,ANKHD1,TMLHE,FNIP1,SYBU,SLC12A2,CPEB4,LARP4,SYNE2,ACTR6,TBC1D15,ZNF23,ADAMTS9" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k3 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.77E-05 2.80E-01 3.08E-04 2.79E-03 30 138 "RNF157,LDLRAD4,RUNX1T1,CDH2,CDO1,SLIT2,NCOR1,APPL1,PYGO1,HDAC9,EDIL3,ETV1,SCML2,FOXF2,MEGF10,PCDH17,RAB40B,IFI16,PCDH8,PFKFB3,GRAMD1C,FAT4,RGS4,ZFHX4,ARMH4,PLCB1,MTCL1,HIF3A,TRPS1,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 40 GSE76381_ESMoleculeCountsPMLog2 5.79E-05 2.81E-01 3.09E-04 2.80E-03 37 185 "C1QTNF3,SPARCL1,CCDC146,CALB1,CBLN1,CDH2,CDO1,COL4A5,CNRIP1,CNTNAP2,ABCA8,TMEM132C,ZMYND10,IQCG,TPPP3,IGFBPL1,CFAP126,LIFR,LRP1B,MID1,NTRK2,CNTN3,PAX6,PDE4D,PLTP,FAT4,ZMAT4,ZFHX4,GALNT10,KIF27,MYCBP2,TCF12,TPM1,ZIC1,DNALI1,FAM13C,NHSL1" Coexpression Atlas PP_RBC_2500_K3 PP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 5.88E-05 2.85E-01 3.13E-04 2.84E-03 33 158 "DPY19L2P4,DDO,SPTBN4,AZGP1,GPR146,LDHD,LONRF2,FCGR3A,HRASLS5,FAM95B1,NFIX,PDE4A,PMP22,ROGDI,RNASE1,TNFRSF19,SMPD3,ASAP3,SLC11A1,OGDHL,ZNF415,DOK5,KLHL7,PCDHGC5,PCDHGB6,PCDHGB2,PCDHGA6,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB3,PDIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_1000_B DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.88E-05 2.86E-01 3.13E-04 2.84E-03 114 776 "DGCR6,ACTN1,NDRG2,ADCY5,TMCC3,SPARCL1,SRPX,LTBP4,PI16,ATP2A2,MYOM1,NRP2,DST,CALM1,CAMK2G,CAST,CLDN10,ENTPD2,DCLK1,LRRFIP1,CDO1,CNTN1,COL4A5,ABI3BP,GDA,PDE4DIP,CNTNAP2,MYADM,DBI,MFAP3L,DDX46,SACS,SPOCK3,DMPK,CPEB2,DTNA,MBNL2,ELN,EPB41L2,MRVI1,FHL1,FLNC,PDLIM5,FUT9,TPPP3,SDCBP2,IGSF5,ADAM28,LYVE1,GNAO1,GP1BB,PRUNE2,MCHR1,STMN2,TPPP,GSN,BVES,AP4S1,SMAP1,IFI16,IL6ST,NEFM,NFE2L2,ALDH1L2,NFIX,NPTX2,PDPK1,PIK3R1,PLEC,FXYD1,FA2H,PPP2R2B,PRKAB2,PRKCB,PTPRB,MEG3,RTN1,RYR3,SATB1,SCN7A,STUM,SH3BGR,FHOD3,PREX2,LIMS2,SLC14A1,CPEB4,RCOR3,SNAP25,FNBP1,DBNDD2,RBM26,ATP10B,KANK1,SYPL1,COBL,TACC1,ENHO,TNS1,TPM1,TPM2,SYNPO2,PPIL6,UCHL1,RBFOX3,AGMO,STOX2,RGS7BP,FAM13C,DOCK8,RTN4,ACTR3B,MSRB3,ZDHHC20" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype Pericyte-A Lungmap Mouse Lung PND3 MatrixFB Subtype Pericyte-A Lungmap CCHMC 6.05E-05 2.94E-01 3.22E-04 2.92E-03 48 263 "SPARCL1,MAP4K3,CDH2,CHN1,CNN3,MAGED1,VCAN,EBF1,EDNRA,RASGRP2,RASL12,TUBA1B,TPPP3,HIGD1B,FERMT2,GUCY1A1,GUCY1B1,KLHL23,KCNK3,KTN1,LIMS1,MAPT,MEST,NFIX,PIK3R1,FXYD1,PCDH18,PMP22,SEPT4,SH3KBP1,NKAIN4,PRKACB,SNRK,C1orf54,RGS4,EMID1,PEAR1,BTBD3,PDZD2,CLSTN2,SSTR2,TCF4,PCDHGA9,SLC35G2,THRA,TNS1,TPM1,TUBA1A" Coexpression Atlas ratio_SC_vs_MESO_500_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 6.19E-05 3.00E-01 3.29E-04 2.98E-03 17 59 "GALNT9,EDIL3,TMEM35A,LRRC17,HPCAL4,CCDC184,SHISAL1,MAP2,NEFM,PCDH18,KLK6,PTPRN,PTPRO,SOX3,LMO3,CRB2,DPYSL5" Coexpression Atlas GSM538228_500 "B cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5- CD45R+, Peritoneal Cavity, avg-2" "Immgen.org, GSE15907" 6.33E-05 3.07E-01 3.36E-04 3.05E-03 58 337 "TXNDC16,FGD2,GAS7,TMEFF1,NRP2,BTK,CACNA1I,CD86,CD38,LY86,CDC42BPB,SIPA1L1,RUBCN,CYBB,MYADM,GUCD1,SLC12A6,EBF1,RASGRP1,FRY,PLXNC1,KCTD3,SRPK3,DENND4A,TLR7,TPPP3,ACSS1,MALT1,RAB30,TPPP,ADAMTS6,MAP4K5,IRAK3,ITGAM,LIFR,MEF2C,AFF1,MYO5A,NUCB2,PPP3CC,PRKCB,DIRAS2,MARCH1,BEND5,LRRK2,RASA3,ST6GAL1,LMBRD1,STAC2,SLC37A2,TCF4,CYB561A3,C9orf85,LAT2,EVI5,SIGLEC10,PLD4,PHTF2" Coexpression Atlas GSM538201_500 "B cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 6.62E-05 3.21E-01 3.51E-04 3.18E-03 59 345 "ADRB2,ZNF608,TXNDC16,FGD2,ATP6V0A1,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,CSNK1G3,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,TLR7,HVCN1,MALT1,RAB30,DCLK2,ADAMTS6,MAP4K5,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,MEF2C,MYO5A,NCF2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,MARCH1,BEND5,LRRK2,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,CYB561A3,TLR4,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K3 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 6.71E-05 3.26E-01 3.55E-04 3.22E-03 69 421 "ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,LDLRAD4,KCNAB3,CCPG1,UBE2L6,VAX2,CRYBB1,CSF1R,SUSD5,TIAM2,DRP2,SNX29,TMTC1,RASA4,PTK2B,DLL3,ABLIM2,FYB1,GAA,TMEM8B,GHR,LYVE1,GNG4,GUCY1B1,ICA1,SCIN,KLHL23,GPR155,MID1,MYH3,NEXMIF,NPR2,PDE4D,PLCL1,TRHDE,PILRA,PRKAR1B,MASP1,ACSS3,ZCWPW1,ZNF493,ZMAT4,PRIMA1,LRFN5,MRAS,SGK1,ASAP3,CCDC92,ARHGAP26,IQSEC2,ADGRL3,FAM189A1,KCNE5,LAMP5,CADM2,DPF3,PRRT4" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.77E-05 3.29E-01 3.58E-04 3.25E-03 18 65 "SLC4A4,ADAM23,CACNA2D1,CFL2,CLCN3,MFAP3L,CPEB2,PDLIM5,IL6ST,ALDH1L2,DIRAS2,RYR3,ZHX3,SYN2,SYNPO2,VLDLR,FAM13C,MSRB3" Coexpression Atlas GSM605826_500 "Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 6.78E-05 3.29E-01 3.58E-04 3.25E-03 64 383 "PTCHD1,ALCAM,FGD2,CASK,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,USP6NL,CYBB,DOCK4,MYADM,CDON,ARRDC4,PLXNC1,PLEKHA1,IGSF6,TLR7,SIRPB1,GATM,HPGDS,RAB30,ADAP1,ZNF496,GSN,FRMD5,LRRC25,IL6R,ITGAM,JAK2,KIT,ADAM22,MYO5A,ABCB1,PLTP,RASGEF1B,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,CYB561A3,SLC44A1,TNS1,NPL,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.96E-05 3.38E-01 3.67E-04 3.33E-03 138 977 "EMILIN3,SYS1,KDM5D,NDRG2,GALNT16,CCDC85A,WDR35,C1QTNF1,ARHGAP20,LTBP4,GPRASP2,CDC42BPA,SMIM29,PHYHD1,CDK10,ADGRB2,BCS1L,CACNA1G,LDLRAD4,CACNA1B,DDR1,CACNA2D1,CAMK2G,ARHGEF25,LONRF2,KCNAB3,CDO1,CRLF1,FOXN3,SLC35F1,ANKRD44,CSF1R,VCAN,RUBCN,SPOCK2,RUSC2,RHOBTB1,DMD,USP3,SHANK1,SNX29,SEMA3D,SUGP2,EGFR,RASA4,TNK2,ELN,TMEM35A,LRRC17,RACK1,CHST15,FCGRT,FGF11,FGF12,FOXF2,VTI1B,SEMA4D,FLYWCH1,TRIM16,TPPP3,FYB1,TMEM8B,GFRA2,PCDH17,PPARGC1A,DHRS4,ZNF276,KCNMB4,GSN,CLASRP,RASSF8,ACOT7,SYNPO,LRRC75A,CELF5,FAM69A,ITPKB,SRSF12,MGAT3,PTOV1,NEXMIF,TCEAL5,NCAM2,NELL2,NFIX,CNTN3,PCDH9,NLGN3,ZFYVE21,TMEM38A,PLCL1,NECAB2,MAGEL2,POU6F1,NKAIN4,PRKAR1B,SLC26A11,PRODH,PTH1R,ZCWPW1,ZMAT4,PBRM1,ARMC5,EMID1,RPS20,MEG3,DGLUCY,FOXRED1,SH3GL3,FERMT1,FHOD3,NLGN1,CDK5RAP3,SLC12A4,SMARCD3,CLSTN2,ANKRD12,MCF2L,ADGRL3,KIAA1107,MGRN1,PHF24,FAM189A1,TMEM9,BEX4,ANKRD24,SYNPO2,KCNE5,TUBB2A,MTCH1,CCDC136,TSPAN11,RBFOX3,NPDC1,NDRG4,CADM2,NAV3,SENP7" Coexpression Atlas GSM605865_500 "Myeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 7.02E-05 3.41E-01 3.70E-04 3.36E-03 71 437 "ALCAM,ABCD2,GAS7,APOC2,CASK,ATP1A3,ATP6V0A1,NRP2,MS4A7,B4GALT6,TPP1,LY86,GDA,CSF1R,CST3,CYBB,MYADM,DBI,EDNRB,PLXNC1,IGSF6,TLR7,SIRPB1,FAM198B,FCGR1A,FCGR3A,FCGRT,PCYOX1,FOLR2,AK8,TPPP3,GALC,GATM,HPGDS,GLUL,HNMT,IGF1,LRRC25,ITGAM,TTYH2,LAMP2,MITF,MSR1,MYO5A,NCF2,P2RX7,TREM2,PLTP,PMP22,LRP12,DRAM2,RASGEF1B,GDPD1,MTMR10,PID1,C1orf54,RNH1,SLC11A1,SPP1,RGL1,SULF2,SLC37A2,DMXL2,KIAA0930,TPCN2,TLR4,TNS1,LAT2,AGMO,PLD4,MARCH8" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.07E-05 3.43E-01 3.72E-04 3.37E-03 24 101 "TMEM108,SLC4A4,MYRF,CALB1,CNTFR,AKAP5,CLIP3,BOC,DNM1,FLNC,TCEAL6,NKD1,KCND2,MAP2,MATN2,MEIS1,NME4,PIK3R1,PCDH18,PTN,MEG3,KCNIP1,PKNOX2,ZFPM2" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.07E-05 3.43E-01 3.72E-04 3.37E-03 24 101 "TAOK1,LCORL,BACH1,PLAA,RBM39,EIF4G1,EMX2,EPB41L2,SMC2,LPAR4,CHIC1,CNOT4,PDPK1,TMLHE,FNIP1,TRA2B,ZC3H13,SYNE2,CBX5,R3HDM1,TSC1,SSBP2,ZNF711,GAN" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO fibroblast_cfr-2X-p05 ECTO blastocyst_vs_ECTO fibroblast-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 7.12E-05 3.46E-01 3.74E-04 3.39E-03 27 120 "AXIN2,ADORA1,PCDH10,RASL11B,NRP2,BMP7,NOG,SLIT2,COL11A2,NRG2,LYPD1,EDNRA,EPHB1,TMEM132C,ITPKB,CLEC18A,SAMD5,PDE1B,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,RELN,TNFRSF19,SNCA,SPP1,DOCK8" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k2_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.17E-05 3.48E-01 3.76E-04 3.41E-03 19 71 "DPP10,CHGB,CNR1,FAM171B,CRMP1,JAKMIP2,STMN2,GUCY1A1,GUCY1B1,NDP,NEFM,CLDN11,GPR85,PRPH,FAT4,RTN1,SNAP25,MTCL1,RPRM" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_200 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.17E-05 3.48E-01 3.76E-04 3.41E-03 19 71 "ADORA1,AMH,SEMA7A,ARHGDIG,JAKMIP2,ELMO1,PLPPR4,DTNA,MRO,ERBB4,TUBB3,FGF13,MYO7A,PGAM2,RASGEF1B,DUSP15,TACC1,THRA,SGK3" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Lungmap Mouse Lung E16.5 Proliferative fibroblast Lungmap CCHMC 7.44E-05 3.61E-01 3.90E-04 3.53E-03 74 461 "LTBP4,ANK2,LCORL,BLM,AP1M1,RUNX1T1,PRC1,RCBTB2,SLIT2,ABI3BP,NSL1,SNCAIP,VCAN,DZIP3,CENPL,FBXL5,EDNRA,EDNRB,ETV1,TUBA1B,FOXF2,TMEM107,SMC2,NSG1,GFRA2,FREM1,GHR,BRD8,DBF4,GPT2,PSIP1,GUCY1B1,HLF,IGF1,KCNK3,LAMA2,STMN1,MEIS1,PTOV1,NDP,NRCAM,GPSM2,PCDH18,PMP22,LRRN3,NKAIN4,PRPSAP2,CNTLN,PTCH1,PTH1R,SPDL1,ZCWPW1,RBBP8,ERI2,UBR7,ZFHX4,ROBO2,RORB,ZC3H14,ATAT1,SEC31A,DZIP1,EPC1,PDZRN3,TTBK2,DNAJC9,CBX5,TMPO,TPM2,TRO,STXBP4,VSNL1,TUBA1A,AAAS" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_500 kidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.56E-05 3.67E-01 3.94E-04 3.58E-03 71 438 "HECW2,C1QTNF1,ADGRF5,PI16,UPRT,CFLAR,CALB1,THSD7A,CD38,CLTB,ARHGEF6,ANKRD44,CSF1,CYBB,ARHGAP24,DGKB,AIF1L,EBF1,EDNRB,TMTC1,OPTN,CALCRL,RCAN2,TLR7,F8,DLC1,ST3GAL6,FGF1,FLT1,UFM1,ST6GALNAC3,GALC,IQGAP2,ERAP1,INPP5K,STMN2,PARD3B,GUCY1A1,SYNPO,LIFR,LMO2,MYO6,SERPINI1,PLCL1,SEPT4,MINDY2,PKIA,SNRK,PTH1R,PTN,PTPRB,PTPRO,RIPOR1,ROBO2,SCN7A,SGK1,FAM81A,PREX2,SLC12A2,CPEB4,LMBRD1,ITPRID2,PLCB1,TMEM150C,SYNE1,TNS2,FRYL,TEK,TLR4,PLEKHH2,PLSCR4" Coexpression Atlas GSM605850_500 "Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 7.56E-05 3.67E-01 3.94E-04 3.58E-03 71 438 "MTUS1,ALCAM,ABCD2,APOC2,CDC14B,CASK,ASPA,ATP1A3,ADAM15,ST3GAL5,CD86,CD38,B4GALT6,LY86,GDA,CSF1R,CST3,CYBB,HDAC9,MYADM,DAPK1,DBI,FAM78B,EDNRB,IGSF6,ETV1,TLR7,F5,FAM198B,FCGR1A,FCGR3A,FCGRT,FER,FGFR1,PCYOX1,AK8,GLUL,ADAP1,IRAK3,VSIG4,HNMT,HP,IGF1,LRRC25,ITGAM,KCNN3,KHK,LAMP2,LIFR,LYPLAL1,MSR1,NCF2,NUCB2,SNX10,PLTP,PMP22,PILRA,DRAM2,PID1,C1orf54,LRRK2,SLC11A1,PLCB1,SLC44A1,TLR4,TRPS1,AGMO,EVI5,PLD4,PLSCR4,NLRP3" Coexpression Atlas gudmap_RNAseq_e15.5_Mesangium_2500_K2 gudmap_RNAseq_e15.5_Mesangium_2500_K2 Gudmap RNAseq 7.56E-05 3.67E-01 3.94E-04 3.58E-03 176 1299 "ABR,EMILIN3,AK2,SPARCL1,ALCAM,LTBP4,PDZD4,AMPH,MYH7B,EPB41L5,PHYHD1,IGDCC4,MARCH3,DYNLL1,CHID1,SLC4A4,ALDH7A1,KIF1A,ADGRB2,MYRF,CA4,CACNA2D1,SLC25A14,ARHGEF25,LDB2,LONRF2,PPT2,MYL6B,FAM189A2,CNTFR,MAGED1,AKAP12,SNCAIP,BOC,MYADM,ARHGAP24,BRINP1,AIF1L,HEPH,SNAP91,ARRDC4,FIS1,EEF1D,TMTC1,EGFR,RASA4,ING4,ELN,TMEM35A,CALCRL,ENO2,COQ7,ERBB4,NCALD,SPEG,ADGRV1,EYA1,CD320,HSPA12B,REEP2,DLC1,RACK1,OLFM1,SCARA3,ATP5PD,VTI1B,FLNC,SLC37A3,POMT1,HVCN1,RASL10A,NSG1,TVP23A,GFER,MMADHC,FREM1,CSDC2,GGTA1P,DHRS4,CACFD1,LINGO1,ATOH8,FAM222A,IRAK3,RASSF8,HAS2,ACOT7,HMGCL,NEGR1,SHISAL1,IGF1,NKD1,KCNH2,KCNK3,GATD1,KHK,LAMA2,CAMK2N2,STMN1,LSAMP,MEIS1,MGAT3,MOV10,COMMD5,BLOC1S2,THYN1,TAGLN3,MXI1,NEFM,NNAT,NME4,NTRK3,PALM,PCSK5,ENPP2,PCDH18,SMIM7,SDK2,SH3KBP1,POLR2F,PPP1R1A,CEP41,MASP1,RELN,PSMA6,PTH1R,PTX3,ZSCAN2,TMEM231,ROGDI,MRPS18A,RNH1,LGI2,ROBO2,SARS,SCP2,SEC14L1,SH3GL3,SHMT2,ST8SIA1,ARFGAP1,SMARCD3,KDM4B,PDZD2,LHPP,CLSTN2,STX1A,SYP,PJA1,TAF9,SIN3B,CUX2,ZFPM2,THRA,TMEM9,HEY1,TK2,TPM2,UBC,UBE2H,FLRT2,PLEKHH2,MTCH1,VLDLR,CLIP2,CLDND1,KCNT2,POLR3H,ZNF189,ADAMTS9,TMEM178A,CIAPIN1,PPP1R3F,ITM2C,PCBP4,DPF3" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k2_500 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.56E-05 3.67E-01 3.94E-04 3.58E-03 26 114 "LDLRAD4,CD86,CD38,LY86,CSF1R,EDNRB,IGSF6,F8,FCGR1A,FYB1,LYVE1,NCKAP1L,IRF8,TM6SF1,MSR1,PTPRB,SGK1,ST8SIA1,SLA,KLHL4,ARHGAP9,TEK,TLR4,NPL,RGS7BP,FAM13C" Coexpression Atlas GSM605805_500 "gamma delta T cells, Tgd.vg5+.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44lo, Small Intestine, avg-3" "Immgen.org, GSE15907" 7.60E-05 3.69E-01 3.96E-04 3.59E-03 68 415 "ADORA2A,MTA3,PKP4,APLP1,RASL11B,BMP7,BAIAP3,HIP1R,CD38,NUMBL,CHN2,OSBPL3,IPCEF1,SIPA1L1,PPP1R16B,ARRDC4,HEYL,OPTN,DENND4A,FDFT1,HVCN1,FYN,IGSF5,GCNT2,GPD2,GPR34,PADI2,FRMD5,ACOT7,HMGCR,CFAP126,AGFG1,SCIN,INPP5B,KIT,STXBP5,HECTD2,LSS,MYO6,NEFH,P2RX7,ZNF827,PDE4A,ABCB1,PLTP,SEPT4,PPP2R2C,PPP3CC,PRKACB,SUSD4,ZMAT4,SEC14L1,MRAS,SH3BP2,FAM102A,ELMO2,PDZD2,SPP1,TEX2,SULF2,KLHL4,FRYL,C18orf54,TRIO,RUNDC3B,VIPR2,LAT2,MARCH8" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.61E-05 3.70E-01 3.96E-04 3.59E-03 33 160 "EPB41L5,CD38,CNTN1,COL9A1,IGSF6,SIRPB1,MRVI1,F8,ST3GAL6,FYB1,IGSF5,FREM1,NEGR1,CLEC18A,TM6SF1,MSR1,CLDN11,OXTR,PTPRB,PTPRO,PTX3,SALL1,SCN7A,SH3BGR,ANKRD6,SLA,DDN,NEK4,TMEM150C,HEY1,TLR4,NPL,SYNPO2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 7.70E-05 3.74E-01 4.00E-04 3.63E-03 15 49 "ATP2B2,KIF1A,SRSF11,IGDCC3,SCRN1,ADGRV1,CLVS1,FUT9,GAD1,SRRM4,PPARGC1A,PCLO,INSM1,MYT1,MAPK10" Coexpression Atlas JC_iEC_2500_K2 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 7.74E-05 3.76E-01 4.02E-04 3.64E-03 55 317 "GALNT13,TMEM108,HAP1,DCLK1,DLGAP1,AKAP5,CRMP1,CRYBB1,KIF26A,AIF1L,PIPOX,IGSF5,GNG4,KAT7,LINGO1,CHST6,PRKAR1B,PRODH,PTPRD,PTPRN,RASGRF2,ZMAT4,RET,ROBO1,RORB,SALL1,SCN8A,SH3GL3,PPM1E,PREX2,SLC9A5,SMARCA4,SNRPN,SOX3,NMNAT2,HECW1,SSTR2,RHBDL3,SYN1,SYN2,SYP,SYT1,TACR1,PCDHA6,TIAM1,TP53BP1,IL34,TUBB2A,UCHL1,UGT8,MGAT5B,VGF,VSNL1,KCNK12,SLC30A3" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k2 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.08E-05 3.92E-01 4.19E-04 3.80E-03 43 230 "NDRG2,ADCY5,ADCY8,SRPX,ARHGAP20,MYOM1,BMPR1B,RGN,DCLK1,MFAP3L,CHRDL1,EDN3,EDNRA,EDNRB,ING4,ETV1,FCGRT,FGF1,FGF12,FHL1,UFM1,GAD1,LYVE1,TNRC6A,GLUL,GSN,HLF,GPR155,MATN2,MYH3,MYO6,VWA2,NPY,PCSK5,NALCN,C1orf54,LGI2,MRAP2,TRIM2,PCDHB9,RPRM,VLDLR,RGS7BP" Coexpression Atlas PCBC_ratio_MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst_cfr-2X-p05 MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 8.38E-05 4.07E-01 4.34E-04 3.94E-03 69 424 "EMILIN3,RNF157,ADD2,WDR35,SEMA6A,APLP1,VAT1L,BLM,PROM1,CRLF1,UBE2L6,RCBTB2,SLIT2,LHX2,HOMER3,CNTFR,COL9A1,IGDCC3,NECTIN3,ZNF385A,CLIP3,CRYM,DPYSL2,EDN1,EDNRB,RASGRP1,EYA1,SPSB4,FLNC,GAD1,MALT1,GRIK5,LINGO1,CPT1C,IFI16,SMAD9,MGAT3,KITLG,MN1,MYCN,BEX5,NELL2,CHAMP1,PRTG,FAM216A,PCDH18,SDK2,FSD1,PPP1R1A,PPP2R2B,RELN,PTH1R,PTPN13,NKAIN1,PRRT2,EMID1,TUNAR,SALL1,TNFRSF19,RASA3,ZNF423,PCDHGB7,PCDHGB6,SSBP2,TCEAL7,DPYSL5,PRTFDC1,TMEM178A,ADAMTS10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 8.42E-05 4.09E-01 4.36E-04 3.95E-03 18 66 "APLP1,THSD7A,IGDCC3,EBF1,SEZ6L2,NRN1,ACSL4,STMN2,IGFBPL1,MAP6,TAGLN3,NEFM,PCSK1,PRTG,ROBO1,RTN1,TNFRSF19,SNCA" Coexpression Atlas facebase_RNAseq_e9.5_MandArch_2500 facebase_RNAseq_e9.5_MandArch_2500 Gudmap RNAseq 8.56E-05 4.16E-01 4.43E-04 4.01E-03 202 1525 "ACTN1,ADORA2A,KIAA1211,INTS2,PCDH19,OSBPL8,TRMT9B,AMPD2,AMPH,AMT,NT5C3B,TMEFF1,ARHGDIG,ARRB1,PTCH2,DPY19L3,BACH1,NRP2,BLM,GPR146,ZNF599,BMPR1B,WASF1,MYRF,CA12,CAMK2A,CARS,LRBA,ARHGEF2,CDC25B,TBRG4,SRSF11,NRXN3,PPT2,FAM19A5,QKI,HOMER3,CNR1,COL9A1,AHCTF1,SMARCAL1,IGDCC3,ZNF385A,HAPLN1,CRYM,PLXNA4,FAM169A,PLCXD3,CTH,GREB1,GPSM1,KIF26A,INTS1,IP6K1,AIF1L,KIAA0753,POM121,SEC16A,DNM1,DMPK,DUSP9,E2F5,EDN1,EIF4G1,USPL1,MFSD10,RABEPK,ERCC2,MRPL37,MRPL10,ETV1,EYA1,TBC1D16,DLC1,CEP78,PRMT5,POLR1B,SPSB4,AMOTL2,MEX3B,FLNC,FLT1,AFF2,NELFCD,CINP,UFM1,FAM49B,RASL10A,ZNF605,PRELID3A,ST6GALNAC3,MTHFD2,SEPT9,AHDC1,FREM1,RUNDC3A,TCERG1,RNPS1,DBF4,GLYR1,GLUL,ADGRA3,GRB10,RNF165,KAT7,PSIP1,ATOH8,IRAK3,AGFG1,HSF2,TJAP1,IBA57,METTL21A,KCNJ5,SFXN5,SMAD9,MATK,MITF,GIT1,MSI1,MYCN,NNAT,NME4,PCBP3,SLC11A2,CHAMP1,OGG1,PALM,CDK18,PDE4A,PDE4D,PDPK1,PKM,KCTD15,GPSM2,NLE1,PSAT1,PPP5C,RASGEF1B,MAPK7,PRODH,ELOVL2,SPDL1,ZIK1,ZSCAN2,NKAIN1,TMEM255A,CCDC40,ROGDI,FIGN,RFX3,KCTD17,NUDT11,RPS6KA2,ST6GALNAC6,SALL1,ZFP2,SH3BP2,MYO18A,SHMT2,ST6GAL1,CCDC92,DHX30,PKNOX2,ZNF334,CXXC4,LIMCH1,SOX11,ZSWIM8,THSD1,CEP68,STX1A,SULF2,MMS19,TAL1,KLHL4,SATB2,DICER1,SIRT1,ZFPM2,C18orf54,HEY1,IL34,TRPS1,CA14,HIRA,UBE3A,USP1,CCDC14,KLC2,ZFP41,EML6,ZNF189,MEIS3,DHX33,SLC38A1,TUBA1A,ADAMTS9,URM1,PCBP4,PHTF2,FBXO36" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.64E-05 4.20E-01 4.46E-04 4.04E-03 13 39 "TMCC3,PCDH10,NRXN3,KIAA0408,NSG1,STMN2,LSAMP,PDZRN4,MEG3,RTN1,UCHL1,CELF4,REEP1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.64E-05 4.20E-01 4.46E-04 4.04E-03 13 39 "RUNX1T1,KIAA0408,PCDH17,PCLO,STMN2,GRIA2,NNAT,REV3L,MEG3,RTN1,SYT1,CELF4,REEP1" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.65E-05 4.20E-01 4.46E-04 4.04E-03 33 161 "ARHGAP20,MYRF,CALB1,CBLN1,DCLK1,CNTFR,HAPLN1,VCAN,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,FREM1,GUCY1A1,NKD1,KCND2,KLHL23,MATN2,MEIS1,NEFM,PCDH18,PTN,TMEM255A,UHRF1BP1L,ADGRL3,KLHL4,ZFPM2,ACTR6,ASXL3,PCDH20,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.81E-05 4.28E-01 4.53E-04 4.11E-03 19 72 "CACNA1A,SEPT7,CNTN1,PHACTR3,ERC2,TAOK3,CSPG5,STMN2,GRIA2,GRIK5,NOVA1,GPR85,TMOD2,LRRN3,MEG3,RTN1,S100B,CNKSR2,CELF4" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500_k3 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.83E-05 4.29E-01 4.54E-04 4.12E-03 26 115 "LCORL,LGR5,PDE8B,ASPA,INSYN2B,SYNJ1,CALB1,CNR1,DRP2,RASGRP1,KCND2,KITLG,NEXMIF,GLIPR1L2,SERPINI1,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,SLC37A2,ZNF711,ZNF23,EMX2OS,REEP1,KLHDC1" Coexpression Atlas GSM538255_500 "Myeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 9.02E-05 4.38E-01 4.63E-04 4.20E-03 69 425 "FMNL2,ADCY6,RNF150,ADRB2,ALCAM,SEMA7A,FGD2,TMEFF1,ADAM23,ST3GAL5,BTK,SPAG9,CD86,SCARB1,ARHGAP22,LY86,FAM149A,SLC4A8,ZNF385A,CDC42BPB,CSF2RA,OSBPL3,CST3,DAPK1,DBN1,CDON,ARRDC4,PLXNC1,RASA4,FCGRT,OLFM1,ZMYND15,GALC,GATM,RAB30,MAP4K5,IRF8,IFI16,LRRC25,JAK2,KIT,ASPRV1,ADAM11,ADAM22,MYO9A,NUCB2,PDE1B,PFKFB3,RASGEF1B,MARCH1,PID1,C1orf54,ROGDI,SNX22,LRRK2,KCNIP3,SEMA6D,ARHGEF40,CCDC88A,SLC11A1,ITPRID2,SULF2,SEPT3,CYB561A3,SLC44A1,TIAM1,TRPM2,SIGLEC10,PLD4" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_500 kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.05E-05 4.39E-01 4.64E-04 4.21E-03 73 456 "ACADM,ACTN1,NDRG2,MTUS1,ADGRF5,SPARCL1,ASPA,SLC4A4,ALDH7A1,MYOM1,CA4,CACNA2D1,CALB1,CLDN10,DCLK1,NDST3,ARHGEF6,CTH,ARHGAP24,DGKB,DMD,EBF1,EDIL3,EDNRA,EDNRB,HEYL,FRY,FAM13A,CERCAM,ELN,CALCRL,RCAN2,RASGRP2,ERBB4,ABCA8,FHL1,PDLIM5,FUT9,IQGAP2,IGSF5,PPARGC1A,GUCY1A1,GUCY1B1,HSPA1L,SLC6A17,KCNJ16,MARK1,MEF2C,NTRK3,PDE3A,ENPP2,PGAM2,SERPINI1,FXYD1,RELN,PTH1R,ZDHHC14,FIGN,SALL1,SH3BGR,SLC4A3,FAM81A,SLC8A1,SLC12A2,LIMCH1,SPP1,PLCB1,TNS1,TPM2,VLDLR,KCNT2,KCNAB1,RGS7BP" Coexpression Atlas gudmap_developingKidney_e15.5_anlage of loop of Henle_500 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.05E-05 4.40E-01 4.64E-04 4.21E-03 66 402 "RALGAPA1,ABHD6,BEND6,APC,EPB41L5,TNRC6C,SLC4A4,MTMR3,CA4,CACNA2D1,CALB1,CLDN10,CLCN3,NCOR1,CRYM,MFAP3L,GOLT1B,ST3GAL6,MED12L,SYNCRIP,SMC2,GALC,SYT17,IGSF5,GCNT2,PPARGC1A,FAM107A,SCIN,KCNJ16,KIF2A,NCOA7,CLEC18A,CHIC1,MITF,MKLN1,CNOT4,NRCAM,PDE1C,PDZRN4,SCHIP1,KANSL1,MAPK4,CNNM2,PTPRO,RASGRF1,REV3L,SALL1,SCN8A,ZFP2,FHOD3,NAPB,FAM126B,ZHX3,MYCBP2,DDN,PRRC2C,MGRN1,WSCD1,ERCC6L2,RGMB,SSBP2,UGT8,VLDLR,ADAMTS9,TMEM178A,DOCK8" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500_k2 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.17E-05 4.45E-01 4.69E-04 4.25E-03 31 148 "ADORA1,PCDH19,DOC2A,CAMK2B,GREB1,USP3,HEYL,EPHB1,ST3GAL6,FKTN,FGFR1,PSD2,TRIM16,IGSF5,BRD8,ADGRA3,DIDO1,PRDM5,CLEC18A,MARK1,TM6SF1,NPY,OXTR,PRTG,PDE1C,DUSP15,EMID1,SALL1,SH3BGR,HEY1,URM1" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 9.17E-05 4.45E-01 4.69E-04 4.25E-03 31 148 "NDRG2,ALCAM,ARHGAP20,RUNX1T1,CBLN1,VCAN,EDNRA,HEYL,EGFR,PLXNC1,LRRC17,NRN1,DLC1,FLNC,GFRA2,FREM1,PPARGC1A,GLI2,GUCY1A1,MAP2,PCDH9,PCDH18,PTCH1,PTN,TMEM255A,ROBO2,MEG3,SULF2,ADGRL3,VSNL1,STOX2" Coexpression Atlas GSM605802_500 "gamma delta T cells, Tgd.vg5+.act.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 9.28E-05 4.51E-01 4.74E-04 4.30E-03 67 410 "MTA3,APLP1,BAIAP3,CAPN3,HIP1R,CD38,RCBTB2,CHN2,OSBPL3,IPCEF1,PPP1R16B,GPRASP1,SPOCK2,PITPNC1,DPYSL2,ARRDC4,HEYL,RASGRP1,DENND4A,ST3GAL6,FDFT1,HVCN1,ST6GALNAC3,FYN,IGSF5,GCNT2,HPGDS,GPD2,GPR34,PADI2,ACOT7,HMGCR,ZDHHC15,CFAP126,AGFG1,SCIN,INPP5B,KIT,STXBP5,HECTD2,LSS,MAP2,MYO6,P2RX7,ZNF827,ABCB1,PLTP,SEPT4,PPP2R2C,PPP3CC,PRKACB,SUSD4,ZMAT4,SEC14L1,MRAS,FAM102A,ELMO2,TRERF1,SPP1,TEX2,SULF2,KLHL4,FRYL,C18orf54,RUNDC3B,VIPR2,LAT2" Coexpression Atlas GSM605862_500 "Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 9.38E-05 4.55E-01 4.79E-04 4.34E-03 71 441 "ALCAM,ABCD2,GAS7,CDC14B,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,CD38,B4GALT6,TPP1,LY86,GDA,CSF1R,CST3,CYBB,MYADM,DAPK1,DNM1,FAM78B,EDIL3,EDNRB,IGSF6,ETV1,TLR7,F5,FAM198B,FCGR3A,FCGRT,FER,FGFR1,PCYOX1,FOLR2,AK8,GAA,GALC,LYVE1,HPGDS,GLUL,VSIG4,HNMT,IGF1,LRRC25,ITGAM,TTYH2,LAMP2,LYPLAL1,MITF,MSR1,TREM2,PLTP,PMP22,LRP12,PILRA,DRAM2,RASGEF1B,GDPD1,PID1,RNH1,LRRK2,SLC11A1,SPP1,NXT2,TLR4,TNS1,LAT2,AGMO,EVI5,PLSCR4,MARCH8" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000_K1 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 9.42E-05 4.57E-01 4.80E-04 4.36E-03 62 372 "EMILIN3,KIAA1324,SRPX,ARHGAP20,CDK10,ADGRB2,ZNF599,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,KCNAB3,CDO1,CRLF1,ABI3BP,ANKRD44,CRYM,CSF1R,DRP2,DUSP9,RASA4,ELN,LRRC17,FCGRT,TRIM16,FYB1,TMEM8B,ZNF276,SYNPO,GPR155,MITF,TCEAL5,NFIX,NPR2,CNTN3,PDE4D,PLCL1,TRHDE,PRKAR1B,ACSS3,IQSEC3,ZCWPW1,ZNF493,ZMAT4,ZFHX4,LRRK2,DGLUCY,MRAS,SH3GL3,ASAP3,SLC8A1,LIMCH1,ADGRL3,SATB2,PHF24,FAM189A1,SYNPO2,TRPS1,TSPAN11,LAMP5,CADM2,DPF3" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_500 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_500 FaceBase_ST1 9.61E-05 4.67E-01 4.90E-04 4.44E-03 58 342 "FZD9,PCDH19,APBA2,CPNE5,CA4,CBLN1,CCNT1,USP2,CDC25B,RAB33A,FAM189A2,FAM19A5,CNTFR,IST1,SCRN1,JAKMIP2,PHF20L1,PCOLCE2,DENND4A,REEP2,SPSB4,CELF1,TPPP3,TOX3,PRRC2B,RNF165,SOX21,UBE2QL1,TOX2,USP51,NKD1,MEIS1,POC1B,AFF1,MYO9A,PALM,PAX6,PCDH9,SLC25A23,NECAB2,ANKHD1,ELOVL2,RDX,PBRM1,ARMH4,TNFRSF19,HSPA4L,KIF21A,CCDC88A,ARFGAP1,SEPT3,WSCD1,TCF12,TMEM121,TRPS1,RPRM,RBFOX3,WNT7A" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.76E-05 4.74E-01 4.97E-04 4.50E-03 48 268 "FMNL2,KLHL13,EPB41L5,LGR5,PPP4R4,INSYN2B,WASF1,SLC16A4,MAGI1,PLXNA4,DAPK1,RASGRP1,KLHL5,EMX2,NRN1,GRIK5,IL6ST,KLHL23,KITLG,MYO9A,NEXMIF,SLC11A2,SERPINI1,PPARA,PPP3CC,GDPD1,FAT4,ZFHX4,PRCD,TNFRSF19,STUM,ABLIM3,SLC4A3,ATF7IP,KDM3A,LHPP,ST5,SLC37A2,RPGRIP1L,CCDC173,DNAH7,ACTR6,KAT6B,ZNF23,ELFN1,LYPD6,REEP1,FRMD6" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k4_200 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.92E-05 4.82E-01 5.04E-04 4.57E-03 10 25 "COL9A1,CRMP1,INSM1,NEFM,PCDH8,RGS4,ZFHX4,SNAP25,RBM26,ZIC1" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000_k2 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.01E-04 4.89E-01 5.12E-04 4.64E-03 50 283 "TMCC3,PLA2G4C,SEC11C,JAZF1,USP2,ABI3BP,MYRIP,GDA,CSNK1E,PHACTR3,PLXNA4,GSDME,SNAP91,SLC12A6,E2F5,MRNIP,EZH1,KAT8,FOXO3,GDF9,TOX2,SYNPO,HNMT,SHISA6,KIT,SYTL4,SETD4,ABCB1,MAPK10,GDPD1,STK32A,SUSD4,RDX,PCMTD2,TRAPPC13,SATB1,KIF16B,CPEB3,SLC14A1,CLSTN2,SYNE2,CAMTA1,MTMR14,PARD3,TBC1D15,TRIM9,NDRG4,FAM47E,FAM13C,DPF3" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype MatrixFB-A Lungmap Mouse Lung PND3 MatrixFB Subtype MatrixFB-A Lungmap CCHMC 1.03E-04 5.00E-01 5.22E-04 4.73E-03 46 254 "ADRA1B,ALCAM,PPP4R4,NRP2,CBR1,CDO1,SLIT2,CNN3,MAGED1,AKAP12,VCAN,DAPK1,BRINP1,MBNL2,PCOLCE2,TUBA1B,DLC1,FGFR3,FHL1,GFRA2,FREM1,FERMT2,GSN,HP,IRF8,KITLG,NFIX,NRCAM,FXYD1,PLTP,PMP22,SEPT4,PTPRD,ROBO2,ABLIM3,PREX2,LIMCH1,TACC1,PDLIM2,TCF4,PCDHGA9,TNS1,TPM1,VLDLR,TUBA1A,ST7" Coexpression Atlas PCBC_ratio_CardioEndothel_vs_SC_cfr-2X-p05 Cardiovascular Endothelial Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.05E-04 5.10E-01 5.32E-04 4.82E-03 232 1791 "ACTN1,TMCC3,AP2A2,MTUS1,HECW2,ADGRF5,SRPX,MARCH4,PCDH10,CDC42BPA,C6orf89,SMIM29,APBB2,ARHGDIA,ARRB1,MARCH3,NUMB,ADAM15,BBS2,NRP2,CFLAR,SYNJ2,AP1M1,IL33,THSD7A,CAST,HIP1R,LDB2,ARHGEF1,CDH2,LRRFIP1,EVI5L,CCPG1,CFL2,TAOK2,ARHGAP22,TPP1,CLTB,HOMER3,IQCK,ABI3BP,ZNF521,CNRIP1,RNF14,ABCG1,CSF1,OSBPL3,CST3,PITPNM3,PPP1R16B,KIAA0040,GPSM1,DOCK4,MYADM,ARHGAP24,RASSF2,DAPK3,GIT2,ELMSAN1,RUSC2,LYPD1,GSDME,RHOBTB1,FAM107B,CD99L2,FIS1,TSPAN5,EDN1,HIPK3,KLHL5,MBNL2,IRAK4,CERCAM,MRNIP,CALCRL,SLC43A2,RRAGB,SIRPB1,NRN1,FAM198B,TAOK3,ST3GAL6,CHST15,FCGRT,SLC9B2,AMOTL2,PRKAG2,FLNC,FLYWCH1,PDLIM5,TRIM16,NSG1,AP4B1,FAM120B,GALC,ERAP1,INPP5K,ACSS1,TUBA8,GGT5,LYVE1,MSL3,GSN,FAM107A,ADAMTS6,SLC2A6,RASSF8,TOX2,ZHX1,FRMD5,MAN1B1,TNFAIP8L3,SYNPO,HMGCL,IFI16,IL6ST,INPP1,ITPKB,KIFC3,LAMP2,LIG4,LIMS1,NCOA7,SMAD1,MAN2A2,MBNL1,TM6SF1,MEF2C,DBNL,NRBP2,MYO5A,NBL1,NRCAM,NUCB2,TBC1D25,CLDN11,PALM,PDE4B,PFKFB3,ZDHHC8,CCSER2,PMP22,SCHIP1,MBOAT7,PPP3CC,PRKACB,PKIA,MAPK3,VPS13C,WBP1L,SNRK,PTPRB,PTPRE,RIPOR1,TTC13,RAP1GDS1,RGS3,RGS4,RGS12,RNASE1,RNH1,RPS6KA2,STK32B,CLIP1,MAPK12,SCP2,PEAR1,SEC14L1,GALNT10,RASA3,SGK1,CCDC92,SEC31A,WDR37,ABLIM3,LIMS2,WDR47,FAM214B,SIRT2,SLC12A2,SLC12A4,LIMCH1,SNCA,FAM219A,ZSWIM8,TEX2,CAMTA2,ITPRID2,THSD1,RGL1,SULF2,TACC1,TAL1,PDLIM2,TCF4,SZT2,DOCK9,TNS2,FRYL,CYB561A3,VWCE,ZMAT3,NACC2,TK2,TLR4,TNS1,RGMB,TRIO,DCBLD1,TTC3,UBC,UBE2H,FLRT2,PLPPR2,TOM1L2,NPDC1,NDRG4,ZBTB38,SPIRE1,GDPD5,RNF103,ADAMTS9,TRIM16L,PCBP4,PLSCR4,RTN4,RSPRY1,MSRB3,SNX14,FRMD6,NETO2,SRGAP2B" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.06E-04 5.15E-01 5.36E-04 4.86E-03 22 91 "FMNL2,KLHL13,CALB1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,EMX2,KLHL23,MYO9A,ZFHX4,HUNK,RASA3,SLC4A3,UHRF1BP1L,ADGRL3,ZFPM2,ACTR6" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k5_500 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.06E-04 5.15E-01 5.36E-04 4.86E-03 22 91 "INTS2,TAOK1,LCORL,INSYN2B,RNF182,CALB1,CNR1,RBM39,DOCK4,DRP2,SCML2,KCND2,KITLG,SERPINI1,PCMTD2,FNIP1,SYBU,CPEB4,LARP4,SYNE2,ACTR6,EMX2OS" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.07E-04 5.18E-01 5.39E-04 4.88E-03 51 291 "ABCF1,BBS2,PTBP2,LRBA,DIS3L,IGDCC3,PREPL,PHF14,ARHGAP32,KIAA0586,IST1,SNX29,WDPCP,KLHL5,EPB41,NSRP1,FDFT1,AFF2,SMC2,UFM1,C15orf41,MMADHC,CIT,KCNJ5,LSS,POC1B,NFE2L2,NFIX,SMIM11A,NTRK3,OCRL,OPA1,CCSER2,DRAM2,DIRAS2,CLIP1,CCDC88A,MBD5,SPATA7,BDP1,SOX11,STXBP4,TRPS1,ZKSCAN5,USP1,ZFP37,ZNF184,UPF3A,EMSY,EVI5,HNRNPA3" Coexpression Atlas GSM538260_500 "Myeloid Cells, DC.8+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2" "Immgen.org, GSE15907" 1.08E-04 5.22E-01 5.43E-04 4.92E-03 67 412 "FMNL2,RNF150,ADRB2,ADGRF5,ALCAM,FGD2,CASK,TMEFF1,N4BP2L1,ADAM23,ST3GAL5,SPAG9,CD86,SCARB1,CD38,SRSF11,LY86,FAM149A,SLC4A8,CSF2RA,CST3,CYBB,HDAC9,DBN1,CDON,ARRDC4,PLXNC1,IGSF6,FCGRT,OLFM1,FLT1,TMEM107,GALC,GATM,RAB30,MAP4K5,IRF8,LRRC25,JAK2,KIT,ASPRV1,ADAM22,MYO9A,NUCB2,PDE1B,PFKFB3,PRKAB2,RASGEF1B,MARCH1,PID1,C1orf54,ROGDI,SNX22,LRRK2,RTN1,MRAS,SLC8A1,CCDC88A,SLC11A1,SLC12A2,FNBP1,SULF2,SEPT3,ADGRL3,CYB561A3,TRPM2,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.08E-04 5.26E-01 5.46E-04 4.95E-03 21 85 "ADORA1,RASL11B,THSD7A,ARHGAP24,AIF1L,CORO2B,SYT17,IGSF5,SYNPO,HP,MAPT,SCHIP1,GDPD2,PTPRO,RIPOR1,FAM184A,DUSP15,SCN7A,DDN,TMEM150C,TMEM178A" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_500_k2 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.09E-04 5.29E-01 5.48E-04 4.97E-03 20 79 "PDE8B,BMPR1B,CALB1,RGN,LRBA,B4GALT6,FAM149A,IPCEF1,TENM1,EMX2,PADI2,L1CAM,VWA2,MAPK4,RASGRF2,RET,SCN8A,HKDC1,RPRM,EMX2OS" Coexpression Atlas PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-OSKM - NLT_cfr-2X-p05 Ectoderm Differentiated Cells-reprogram_NA_vs_Ectoderm Differentiated Cells-reprogram_OSKM - NLT-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.09E-04 5.29E-01 5.48E-04 4.97E-03 20 79 "ADORA1,PCDH10,RASL11B,LARGE1,COL11A2,NRG2,LYPD1,EDIL3,EDNRA,TMEM132C,ITPKB,KIT,CLEC18A,SAMD5,IRX1,ZFHX4-AS1,LRRN3,RELN,ZFHX4,DOCK8" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-2fold-vs-M DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-2fold-vs-M_top255_255 Gudmap Mouse MOE430.2 1.10E-04 5.33E-01 5.52E-04 5.00E-03 43 233 "AXIN2,PCDH10,SEMA4G,BCL7A,MTMR2,LARGE1,CRLF1,ABCG2,PCYT1B,NCOR2,GREB1,SCRN1,PITPNC1,TIAM2,USP3,DUSP9,TBC1D16,TMEM132C,TUBB3,CEP78,DCTN2,ZBED3,MEGF11,SPIN1,GLI2,NRCAM,RGS12,KIRREL1,HES6,PPM1E,FHOD3,DZIP1,POGZ,NEK4,SULF2,SYNE2,SIN3B,SATB2,CA14,TSC2,WNT7A,ZNF184,ZNF213" Coexpression Atlas GSM538252_500 "Myeloid Cells, DC.8+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.10E-04 5.33E-01 5.52E-04 5.00E-03 68 420 "FMNL2,ADCY6,RNF150,ADRB2,ALCAM,FGD2,CASK,TMEFF1,ADAM23,ST3GAL5,BTK,SPAG9,CD86,SCARB1,LY86,FAM149A,SLC4A8,ZNF385A,CDC42BPB,CSF2RA,OSBPL3,CST3,HDAC9,DBN1,CDON,ARRDC4,PLXNC1,RASA4,FCGRT,OLFM1,ZMYND15,GALC,GATM,RAB30,MAP4K5,IRF8,LRRC25,JAK2,KIT,ASPRV1,ADAM22,MYO9A,NUCB2,PDE1B,PFKFB3,RASGEF1B,MARCH1,PID1,C1orf54,ROGDI,ZDHHC14,SNX22,LRRK2,KCNIP3,RTN1,SEMA6D,MRAS,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,FNBP1,SULF2,SEPT3,CYB561A3,TRPM2,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_200 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.13E-04 5.49E-01 5.67E-04 5.14E-03 34 170 "PCDH19,ARHGAP20,VAT1L,CA4,CHGB,CNTN1,CRYM,EBF1,MRVI1,RASL10A,FYB1,MEGF10,GALC,IGSF5,FREM1,PTPRT,FAM19A2,NEGR1,CLEC18A,MN1,NCF2,OXTR,PDE1C,PTPRO,PTX3,ZFHX4,SALL1,SCN8A,SLC14A1,CLSTN2,NEK4,TEK,HEY1,NETO1" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K3 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.13E-04 5.50E-01 5.68E-04 5.14E-03 46 255 "SPTBN4,GPC2,LRBA,CCPG1,CLIP3,SNCAIP,GSDME,FAM107B,CEP85L,ETV1,TMEM132C,HPCAL4,AFF2,SYT3,SMC2,STAU2,HIGD1B,ZNF276,HLF,ICA1,IGF1,KNDC1,KCNJ5,MAN2A2,TCEAL5,NFE2L2,NPY,PDE4D,DIRAS2,CNTLN,NWD1,REV3L,PLPPR3,DGLUCY,PREX2,DHX30,TET1,SMARCC2,BDP1,ARHGAP26,SATB2,SYNE1,PHF24,AMACR,STXBP4,TRPS1" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_200 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.15E-04 5.57E-01 5.74E-04 5.20E-03 35 177 "HECW2,AMH,SEMA7A,GAS7,LGR5,PPP4R4,ARHGDIG,CADPS,CACNA2D2,CLTB,VCAN,SCRN1,ELMO1,DTNA,MRO,PLXNC1,CERCAM,ERBB4,PTK2B,FGF13,GATM,PPARGC1A,GPR37,KLHL23,KITLG,RASGEF1B,ROBO1,RPS6KA2,MRAS,ST6GAL1,SPP1,TACC1,SGK3,ADAMTS9,WNK3" Coexpression Atlas Arv_SC-LF_1000 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000 PCBC 1.17E-04 5.66E-01 5.82E-04 5.28E-03 138 988 "KCNH8,SYN3,TMEM132B,ADCY5,ADCY8,GALNT13,ADD2,UNC5A,OLMALINC,SEMA6A,PDZD4,DPP10,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,AZGP1,CLDN10,SYNGR3,DLGAP1,PLEKHB1,FAM189A2,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,IGDCC3,CRYBB1,LRRC3B,RIMS4,CNTNAP2,ERC2,SEC14L5,KATNAL2,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,DPP6,SLC25A18,EDNRB,AASS,RASGRP2,PIPOX,ADGRV1,PRAM1,PPP1R1B,OLFM1,SPSB4,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,GNG4,LPAR4,COQ10A,LINGO1,RNFT2,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KCNN1,KCNN2,KIF5A,CAMK2N2,MATK,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,SEMA5B,JAKMIP1,MAGEL2,EPB41L4B,PPP2R2B,NKAIN4,LAMA1,GDPD2,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,MRAP2,SGSM1,MEG3,SALL1,TMEM200C,SH3GL3,PREX2,SEPHS1,TET1,SNRPN,SOX3,SOX15,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,SLC19A3,CCDC173,RNF175,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,CA14,RPRM,VGF,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000_k4 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.19E-04 5.77E-01 5.94E-04 5.38E-03 62 375 "RALGAPA1,ABHD6,TAOK1,FAM135A,OGT,APAF1,APC,EPB41L5,TNRC6C,SLC4A4,WASF1,CACNA2D1,DCLK1,CFL2,CLCN3,COL4A5,RBM39,DZIP3,PLPPR4,SEMA3D,EIF5,EZH1,MED12L,SUCO,SYNCRIP,SMC2,PDLIM5,IQGAP2,TUBGCP4,SRCAP,PPARGC1A,GRB10,ICA1,IL6ST,KIF2A,CHIC1,KITLG,MKLN1,PFKFB2,PIK3C2A,PSAT1,SCHIP1,KANSL1,REV3L,TRA2B,SLC8A1,LIMCH1,FAM126B,BDP1,ZHX3,MYCBP2,KANK1,PRRC2C,VPS13A,MGRN1,ERCC6L2,RGMB,SSBP2,UGT8,VLDLR,DOCK8,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.22E-04 5.92E-01 6.08E-04 5.51E-03 66 406 "ADORA1,OGT,APC,PDE8B,BMP7,CA4,CALB1,RGN,CRLF1,B4GALT6,CLCN3,FAM149A,COL9A3,SLC35F1,RBM39,CRYM,IPCEF1,CNTNAP2,CTH,ARHGAP24,MFAP3L,DDX46,SEMA3D,EIF5,EIF1,EMX2,SPSB4,FGF12,SYNCRIP,SMC2,PDLIM5,RASL10A,GALC,PPARGC1A,MAP7D2,CNTRL,GRB10,ICA1,SCIN,KCNJ16,L1CAM,KITLG,NEK1,VWA2,PIK3C2A,KANSL1,MAPK4,LAMA1,RASGRF2,RET,REV3L,CLIP1,SALL1,SCN8A,HKDC1,FHOD3,STX1A,TMEM150C,WSCD1,ERCC6L2,SSBP2,RPRM,UGT8,VLDLR,VSNL1,ZNF23" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K1 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 1.23E-04 5.95E-01 6.11E-04 5.54E-03 32 157 "TTLL9,ZNF599,CA4,CBLN1,FAM19A5,CHRDL1,PLEKHA1,PIPOX,NOP56,LPAR4,NKD1,CDH20,IPO5,AQP11,PRTG,PKM,PLTP,MAGEL2,IRX1,GDPD2,PTPN13,RPL15,SALL1,TNFRSF19,NUBPL,PKNOX2,SNRPN,NMNAT2,PBLD,MTCL1,BEX4,ZIC2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K4 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.26E-04 6.12E-01 6.27E-04 5.69E-03 22 92 "NCKAP5,LTBP4,GPRASP2,SLC25A14,LONRF2,SRSF11,NRXN3,CNTFR,DMD,SHANK1,TMEM35A,CHST15,PPARGC1A,NEXMIF,NCAM2,NELL2,PCDH9,POU6F1,NLGN1,CLSTN2,KCNE5,SENP7" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.28E-04 6.22E-01 6.38E-04 5.78E-03 18 68 "DCLK1,COL9A1,CRMP1,GSDME,TUBB3,MEGF10,STMN2,INSM1,TAGLN3,NEFM,PCDH8,FIGN,RGS4,ZFHX4,CSRNP3,SNAP25,RBM26,ZIC1" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k4 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.30E-04 6.29E-01 6.44E-04 5.84E-03 36 185 "PDE8B,PROM1,BMP7,BMPR1B,CALB1,CRLF1,B4GALT6,SLIT2,COL9A3,IPCEF1,CNTNAP2,KIAA0040,DUSP9,EMX2,SPSB4,FGF12,RASL10A,MAP7D2,FRMD5,L1CAM,KITLG,VWA2,MAPK4,LAMA1,EML5,RASGRF2,RET,FHOD3,FAM81A,LIMCH1,TMEM150C,WSCD1,DCBLD1,RPRM,VSNL1,EMX2OS" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.30E-04 6.30E-01 6.44E-04 5.84E-03 37 192 "KLHL32,PROM1,PTBP2,IQCK,SLC4A8,IGDCC3,KATNAL2,JAKMIP2,DDX46,CASP8AP2,MAMLD1,NSRP1,FGFR3,KIAA1841,TCERG1,MAP7D2,CIT,USP51,KTN1,NEFM,NOVA1,NTRK2,GPR137C,FAM98B,SEMA5B,ELOVL2,EML5,CLIP1,SAFB,NLGN1,GKAP1,BDP1,NEK4,SYNE2,SYN1,CCDC173,ZNF23" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500_2 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500_2 FaceBase_ST1 1.31E-04 6.36E-01 6.50E-04 5.89E-03 44 242 "PCDH19,PITPNM2,APBA2,CBLN1,USP2,CDC25B,RAB33A,FAM189A2,FAM19A5,JAKMIP2,PHF20L1,ING4,PCOLCE2,DENND4A,REEP2,SPSB4,CELF1,TPPP3,NEU3,TOX3,PRRC2B,SOX21,UBE2QL1,TOX2,NKD1,MEIS1,AFF1,MYO9A,PALM,PAX6,PCDH9,SLC25A23,ANKHD1,ELOVL2,PBRM1,ARMH4,TNFRSF19,HSPA4L,CCDC88A,SEPT3,WSCD1,TCF12,TMEM121,RBFOX3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_1000 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.40E-04 6.79E-01 6.93E-04 6.28E-03 112 776 "NDRG2,TMCC3,PLEKHH1,USP31,ADGRF5,C1QTNF3,SPARCL1,ARHGAP20,PI16,APC,SLC4A4,ATP2A2,MYOM1,DST,IL33,CA8,CACNA2D1,CALB1,CAST,ENTPD2,CHGB,COL9A1,ABI3BP,AKAP12,GDA,OSBPL3,IPCEF1,CNTNAP2,KIAA0040,ELMO1,MFAP3L,CHRDL1,CPEB2,ARRDC4,EBF1,EDNRB,HIPK3,SEMA3D,OPTN,ELN,CALCRL,MRVI1,DLC1,PRKAG2,PDLIM5,FUT9,SDCBP2,GALNT15,IGSF5,ADAM28,GFRA2,LYVE1,RAB40B,TPPP,GSN,IRAK3,RASSF8,HNMT,IFI16,RBPJ,IL6ST,SLC35G1,LSAMP,MATN2,MSR1,NFE2L2,NPTX2,NTRK2,CLDN11,PIK3C2A,JAKMIP1,FA2H,DIRAS2,PTPRB,PTX3,TMEM255A,ZDHHC14,RGS4,LGI2,RYR3,S100B,SCN7A,SH3BGR,CPEB3,ABLIM3,SLC14A1,FNBP1,ZHX3,ATP10B,CLASP2,ELOVL4,ARHGEF9,TEK,ZFPM2,SLC44A1,TLR4,RASD2,TPM2,RGMB,SYNPO2,TRPS1,PPIL6,RBFOX3,PCDH20,AGMO,KCNAB1,PLSCR4,RGS7BP,FAM13C,DOCK8,MSRB3,SOCS4" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000_k5 DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.41E-04 6.85E-01 6.98E-04 6.33E-03 40 214 "AGT,SORCS2,C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,CBLN1,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,FYN,GATM,GPR37,IL6ST,TTYH2,MEF2C,MYO7A,NFIX,SEMA5B,PLEC,FXYD1,PTPRE,MEG3,SPP1,SULF2,TBL1X,SIN3B,TNS1,NR2C2,TST,UBTF" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500 FaceBase_RNAseq 1.41E-04 6.86E-01 6.98E-04 6.33E-03 76 486 "EMILIN3,NDRG2,KIAA1324,ARHGAP20,LTBP4,GPRASP2,CDK10,BACH1,ADGRB2,BMPR1B,CACNA1G,CA4,CA12,CACNA1B,CDO1,TBRG4,CRLF1,SRSF11,LHX2,IGDCC3,CRYM,CSF1,CSF1R,GREB1,SEMA3D,EGFR,ELN,EMX2,LRRC17,DLC1,FCGRT,FGF11,TPK1,FYB1,ACSS1,GATM,PCDH17,PPARGC1A,ZNF276,GPT2,GSN,RABL2A,SYNPO,INPP1,MBNL1,ADAM11,SRSF12,NCAM2,NELL2,NFIX,NNAT,CNTN3,PCDH9,PRTG,PLCL1,SCHIP1,POLR2F,PRODH,ZMAT4,RTN1,SALL1,MAST1,LIMCH1,PLCB1,ADGRL3,PHF24,FAM189A1,HEY1,NR2E1,KCNE5,TSPAN11,ZIC2,LAMP5,CADM2,PCBP4,SENP7" Coexpression Atlas GSM854315_500 "Myeloid Cells, MF.169+11chi.SLN, CD11b+ CD169+ CD11chigh, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.42E-04 6.90E-01 7.02E-04 6.36E-03 63 385 "FMNL2,ALCAM,FGD2,ADAM23,ST3GAL5,DDR1,CD86,B4GALT6,LY86,FAM149A,GDA,CSF1R,CSF2RA,CST3,CYBB,DOCK4,MYADM,DBN1,PLXNC1,RASA4,IGSF6,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,GATM,GCNT2,GFRA2,RAB30,ADAP1,GSN,IRF8,IFI16,LRRC25,ITGAM,KIT,LIFR,ADAM11,MYO9A,P2RY13,NCF2,PLTP,PILRA,RASGEF1B,MARCH1,PID1,C1orf54,ROGDI,SNX22,LRRK2,KCNIP3,RTN1,CCDC88A,RGL1,SULF2,SEPT3,KIAA0930,TIAM1,TRIO,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k4_500 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.43E-04 6.95E-01 7.06E-04 6.40E-03 29 138 "GAS7,MARK4,ATP1A1,DST,ST3GAL5,RGN,SCRN1,DTNB,ERBB2,FAM198B,CAMKK2,PPARGC1A,ADGRA3,GPR37,NCOA7,MAN2A2,MSI1,NRBP2,PRKCB,SH3TC2,ROBO1,GLDN,RPS6KA2,MRAS,ST6GAL1,SPP1,ADHFE1,SLC38A1,ADAMTS9" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.48E-04 7.18E-01 7.29E-04 6.61E-03 27 125 "SPARCL1,ALCAM,ARHGAP20,CACNA1G,CBLN1,SLIT2,HAPLN1,VCAN,ARMCX2,EDNRA,EGFR,LRRC17,ST6GALNAC3,GFRA2,FREM1,GHR,GLI2,GUCY1A1,LAYN,PCDH9,LAMA1,TMEM255A,ROBO2,ARMH4,SULF2,VSNL1,ZNF711" Coexpression Atlas gudmap_kidney_e10.5_UretericTrunk_HoxB7_1000 kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.49E-04 7.26E-01 7.36E-04 6.67E-03 115 802 "PCDH19,ADGRF5,CEP126,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,BARD1,BCL7A,NRP2,ZNF599,PROM1,CA4,CA8,CALB1,MTMR7,CD38,LRBA,RCBTB2,CHN2,B4GALT6,SLIT2,FAM149A,HAPLN1,FAM169A,ARHGAP24,HDAC4,CENPL,ARMCX4,GSDME,CHRDL1,DPP6,DUSP9,E2F5,EDIL3,SEMA3D,PLEKHA1,EMX2,ERBB2,SH3YL1,ACSL4,RACK1,FDFT1,SPSB4,FHL1,SEMA4D,FLT1,PSD2,C2orf88,SYT17,C15orf41,IGSF5,GGTA1P,PPARGC1A,RAB30,TOX3,MAP7D2,LPAR4,FAM19A2,PADI2,JAK2,SLC35G1,KCNJ16,L1CAM,LMO2,CHIC1,TM6SF1,KITLG,MSI1,THYN1,MYO6,TCEAL5,NOVA1,NRCAM,PAX6,PRTG,PLCL1,SEPT4,GDPD1,LAMA1,PTH1R,SPDL1,PTPN13,PTPRB,EML5,TUG1,TMEM255A,BEND5,RET,FIGN,NUDT11,KIF21A,SHMT2,FHOD3,SLC8A1,SOX11,THSD1,ZC4H2,KANK1,NUDT10,TMEM150C,KLHL4,CUX2,TEK,C18orf54,SLC44A1,BEX4,DCBLD1,CA14,RPRM,UCHL1,VLDLR,VSNL1,ZNF711,SLC38A1,NHSL1" Coexpression Atlas Arv_EB-LF_2500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.50E-04 7.28E-01 7.37E-04 6.68E-03 134 960 "CCDC85A,BEND6,PCDH19,KCTD16,SORCS2,SRPX,AMPH,DPP10,LRCH2,APLP1,APOC2,LGR5,ARSE,INSYN2B,SLC4A4,RNF182,NRP2,CACNA1G,MYRF,CABP7,CBLN1,CCK,CDR1,LHX2,CNR1,CNTFR,COL11A2,AKAP5,IGDCC3,CRHBP,HAPLN1,SNCAIP,PYGO1,LYPD1,PLPPR4,SPOCK3,DLX1,DNAH9,DRP2,DUSP9,EBF1,EDIL3,SEZ6L2,EDN3,SEMA3D,EMX2,LRRC17,CLVS1,TMEM132C,HPCAL4,FOXF2,FLT1,PSD2,SRRM4,CPLX2,GFRA2,FREM1,GHR,RUNDC3A,CCDC184,STMN2,GRIA2,C1QL4,GRIN2D,GRM8,PTPRT,ADAMTS6,BACH2,IGFBPL1,C2orf72,SLC6A17,INSM1,CDH20,KCNQ3,CLEC18A,MAP6,MATN2,TAGLN3,LAYN,MYT1,NCAM2,NEFM,NELL2,NNAT,NPY,NTRK2,OXTR,PAX6,PCDH8,ENPP2,PDZRN4,TRHDE,NECAB2,MAGEL2,NKAIN4,PRPH,MASP1,PSD,LAMA1,ELOVL2,PTPRD,PTPRH,PTPRN,PTPRO,PTX3,TMEM255A,RGS4,ZFHX4,HUNK,KCNIP1,RTN1,LRFN5,TNFRSF19,SEC31A,PKNOX2,TRIM67,DMRTC1,SNAP25,PEG10,CLSTN2,SST,SYT5,ADGRL3,PCDHGB6,ASXL3,RIMBP2,DOK6,ZIC1,CRB2,MKRN3,DPYSL5,DNAH10,ST8SIA2,PRRT4" Coexpression Atlas BM Top 100 - thalamus BM Top 100 - thalamus Body Map 1.52E-04 7.36E-01 7.44E-04 6.75E-03 17 63 "CALB1,SYNGR3,DLGAP1,GABRG2,GAD1,CPLX1,GPR37,STMN2,MAP4,NEFM,NEFH,SLC8A1,SYT1,CCDC136,P2RY12,ZIC1,CPNE4" Coexpression Atlas fallopian tube fallopian tube Human Protein Atlas 1.52E-04 7.36E-01 7.44E-04 6.75E-03 66 409 "KLHL32,ADCY8,NME5,CC2D2A,CCDC146,LGR5,STK33,CCDC74A,TTLL9,BAIAP3,CACNA1B,CCDC151,TOGARAM2,SLITRK5,LYPD1,KIF19,DNAH9,EMX2,ERBB4,ANKMY1,CORO2B,ZMYND10,FGF14,SCARA3,IQCG,AK8,TPPP3,MEGF11,GPR162,SPACA9,PTPRT,RABL2A,FAM107A,CFAP126,KNDC1,NME9,PACRG,MAP6,EFHB,CCDC13,NELL2,VWA2,HYDIN,KLK6,TMEM231,CCDC40,NWD1,CRTAC1,NEK11,PLPPR3,TUNAR,SLC22A4,ANKFN1,SOX3,TSNAXIP1,DOK5,VWCE,DNAH7,CDH22,PPIL6,SLC47A2,DNALI1,MDH1B,FAM47E,DNAH10,FBXO36" Coexpression Atlas GSM538222_500 "B cells, B1a.PC, IgD+ IgM+ CD19+ CD43+ CD5+ CD45R+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.52E-04 7.37E-01 7.44E-04 6.75E-03 55 325 "ABHD6,SORCS2,TXNDC16,SEMA7A,FGD2,GAS7,CDC14B,TMEFF1,NRP2,BTK,CACNA1I,CD86,CD38,B4GALT6,LY86,RUBCN,CYBB,MYADM,GUCD1,EBF1,RASGRP1,FRY,PLXNC1,SRPK3,DENND4A,TLR7,AK8,TPPP3,ACSS1,MALT1,RAB30,TPPP,ADAMTS6,IRAK3,ITGAM,LIFR,MEF2C,AFF1,MYO5A,NUCB2,PPP3CC,DIRAS2,MARCH1,LMBRD1,LHPP,SLC37A2,TCF4,DMXL2,CYB561A3,C9orf85,LAT2,EVI5,SIGLEC10,PLD4,PHTF2" Coexpression Atlas PCBC_ratio_MESO-5_vs_SC_1000 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000 PCBC 1.53E-04 7.43E-01 7.50E-04 6.80E-03 138 994 "KCNH8,ADORA1,C1QTNF1,PCDH10,TRMT9B,APOC1,LGR5,ARHGDIG,ARRB1,ARSE,CFLAR,BMP7,ST3GAL5,BTK,CASTOR3,C5,MYRF,LDLRAD4,CFAP410,CDH2,NOG,CNR1,COL4A5,NRG2,CRHBP,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGEF4,GPSM1,PYGO1,ARHGAP24,ELMO1,SV2B,SPOCK3,DYNC1I1,DTNA,CNNM1,YAF2,CERCAM,ERBB4,RASL12,FAM198B,DLC1,FGFR3,AMOTL2,RASL10A,TPPP3,DENND2A,GAD1,GATM,ADAM28,FREM1,PCDH17,GGT5,PPARGC1A,HPGDS,GPR37,TMEM121B,FAM222A,HAS2,NCKAP1L,HP,LRRTM1,ITPKB,CDH20,KCNF1,KCNJ5,KIFC3,KIT,LIFR,SMAD9,MAN2A2,MATN3,MITF,MSR1,MXI1,MYT1,NBL1,PCBP3,NRCAM,SMIM11A,SETD4,CLDN11,OXTR,PALM,CNTN3,PAX6,PCDH8,PDE4D,ENPP2,GPSM2,PDZRN4,PMP22,LRP12,PPP3CC,MAPK10,RELN,LAMA1,PTH1R,ELOVL2,RIPOR1,FAM184A,RNASE1,MELTF-AS1,SH3BGR,CCDC92,ST8SIA1,ANKRD6,SLC9A5,SMARCD3,MCF2L2,NFASC,ITPRID2,SSTR2,SSPO,TMEM150C,PHF24,FAM189A1,TNS2,ZFPM2,RP9P,PIK3R5,LRRC24,TRO,TRPM2,TTC3,RPRM,FLRT2,VLDLR,WIPF1,CLIP2,LAT2,KCNK12,ANKS1B,SLC30A4,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_100 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.54E-04 7.49E-01 7.55E-04 6.85E-03 21 87 "C1QTNF3,DPP10,IL33,CACNA2D1,SEMA3D,TMTC1,CHL1,RASSF8,IFI16,KCND2,NOVA1,PCDH8,RELN,SALL1,CSRNP3,SCN7A,ST8SIA1,NEK4,PCDHB9,ASXL3,PCDH20" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_500 kidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.54E-04 7.50E-01 7.55E-04 6.85E-03 67 417 "NDRG2,USP31,HECW2,ADGRF5,SPARCL1,SEMA6A,AMPD3,SEMA7A,APBB2,ADAM15,NRP2,CA8,CH25H,LDB2,CD38,CHN2,PPP1R16B,DOCK4,PITPNC1,NR1D2,ECM2,EBF1,EDNRB,SEMA3D,TMTC1,CALCRL,F8,ST3GAL6,FLT1,ST6GALNAC3,ERAP1,INPP5K,PCDH17,GGTA1P,IFI16,IGF1,SCIN,ITPKB,STXBP5,LMO2,TM6SF1,MEF2C,MEIS2,MYO6,NFE2L2,PLTP,MINDY2,SNRK,PTPRB,RIPOR1,LRRK2,SGK1,PREX2,SLC14A1,LIMCH1,LMBRD1,RGL1,PLCB1,KLHL4,TCF4,SYNE1,TNS2,TEK,TLR4,TNS1,AGMO,PLSCR4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgle_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgle_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.56E-04 7.55E-01 7.60E-04 6.89E-03 58 348 "ZNF608,SPARCL1,DNAJC27-AS1,SGCE,ARHGEF25,CBLN1,CDH2,CDO1,CDR1,COL4A5,COL9A1,ZNF521,CNRIP1,SLC35F1,GDA,CNTNAP2,PABPC5,SEZ6L2,ING4,ERBB2,NRN1,ABCA8,TMEM132C,TMEM164,TMEM107,ERGIC3,GRM8,ITPKB,KCNQ3,KIT,LAMP2,LRP1B,MID1,NUCB2,CNTN3,PAX6,PKM,PLTP,ZFHX4-AS1,GDPD2,USP47,FAT4,RFX3,ZFHX4,S100B,GALNT10,KANSL3,SYNE2,PDLIM2,NR2F1-AS1,TCF12,AKTIP,CA14,ZIC1,ZIC2,DNALI1,ADAMTS9,NHSL1" Coexpression Atlas GSM538268_500 "Myeloid Cells, DC.IIhilang+103+11blo.SLN, MHCIIhi CD11c+ Langerin+ CD103+ CD11b-, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.57E-04 7.60E-01 7.64E-04 6.92E-03 64 394 "FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,STOML1,LY86,SLC4A8,ABCG1,CSF1,PNPLA8,RASSF2,GUCD1,DNM1L,EBI3,PLXNC1,ENO2,MTSS1L,MEX3B,ZMYND15,MTHFD2,RAB30,ADAP1,SLC2A6,HSF2,IRF8,SCIN,INSM1,KTN1,ASPRV1,ADAM11,NPR2,PFKFB3,CCSER2,PLCL1,EML5,ROGDI,ZDHHC14,RGS12,SEMA6D,ARHGEF40,CCDC88A,SAMSN1,ST5,STXBP1,TMEM150C,ARC,ATMIN,PHF24,SLC44A1,SYNPO2,ZBTB38,EML6,SPIRE1,ITM2C" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_200 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.57E-04 7.62E-01 7.64E-04 6.92E-03 32 159 "KLHL13,PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,NRN1,FLNC,AFF2,FREM1,GUCY1A1,TCEAL6,KCND2,KLHL23,MAP2,KITLG,SERPINI1,PCDH18,TMEM255A,STUM,SLC4A3,ADGRL3,ZFPM2,ACTR6,VSNL1,LYPD6,WNK3" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k1_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.57E-04 7.62E-01 7.64E-04 6.92E-03 32 159 "RNF182,FUBP1,CALB1,CDH2,CHGB,SOCS6,COL9A1,HAPLN1,ZNF804A,ALKBH8,EDIL3,EMX2,CHST15,MEX3B,CBX1,FAM19A2,MEIS2,PRTG,GPR85,PTX3,ROBO1,ROBO2,CSRNP3,ZKSCAN3,RBM26,RGL1,SYPL1,KLHL4,ASXL3,TPM1,STXBP4,SMARCAD1" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k3_1000 kidney_P1_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.59E-04 7.71E-01 7.73E-04 7.00E-03 19 75 "MTUS1,TXNDC16,CC2D2A,ALCAM,CASK,ADAM23,BCHE,IL33,ABI3BP,AKAP12,SPOCK2,ARRDC4,EXTL2,ADAMTS6,MMP16,NFIX,NPR2,SULF2,TPM2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k5 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.60E-04 7.75E-01 7.76E-04 7.04E-03 11 31 "CHGB,SPOCK3,TUBB3,STMN2,IFI16,MAP4,MYH3,NEFM,MAPK10,PRPH,SNAP25" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.63E-04 7.90E-01 7.90E-04 7.16E-03 15 52 "NRP2,SEPT7,CRMP1,DPP6,TAOK3,NSG1,STMN2,GRIA2,GRIK5,BEX5,NNAT,MEG3,RTN1,SNAP25,CELF4" Coexpression Atlas ratio_SC_vs_ECTO_2500_K4 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 1.65E-04 7.99E-01 7.99E-04 7.24E-03 55 326 "EMILIN3,KLHL32,ADCY5,CCDC85A,C1QTNF1,SPARCL1,ATP1A3,AZGP1,GPR146,LDHD,IL33,CH25H,RUNX1T1,ARHGEF25,EVI5L,CRYM,PLXNA4,BOC,MYADM,GRIN3A,FAM78B,KRBA2,EDNRB,HSPA12B,TMEM132C,GALNT15,IP6K3,ALDH1L1,GNAO1,COQ10A,NEGR1,IDH3A,MYLK2,LRRC25,KIAA1755,ITGAM,TTYH2,MT1M,MX1,TMEM38A,FXYD1,PLTP,VSTM2L,FITM2,DUSP15,SGSM1,LRRK2,SSTR1,TIMP4,RASD2,SYNPO2,VIPR2,TRIM9,SLC30A3,PPP1R3F" Coexpression Atlas PCBC_SC_blastocyst_500 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 1.73E-04 8.40E-01 8.38E-04 7.60E-03 77 497 "SYN3,TMEM132B,ADD2,UNC5A,PDZD4,RASL11B,KIF1A,LDHD,CLDN10,FAM19A5,IGLON5,COL9A1,GAL3ST1,RIMS4,CNTNAP2,SEC14L5,BRINP1,DPP6,AASS,PIPOX,ADGRV1,PPP1R1B,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,GNG4,LPAR4,LINGO1,IGFBPL1,C9orf129,SHISA6,CELF5,ZIC5,KCND2,KIF5A,CAMK2N2,MATK,CHST6,FXYD7,NELL2,NPTX1,SEMA5B,JAKMIP1,EPB41L4B,PPP2R2B,NKAIN4,LAMA1,GDPD2,TMEM145,NKAIN1,HUNK,SALL1,TMEM200C,PPM1E,SNRPN,SOX3,SEPT3,ARC,COBL,CHST8,GALNT17,ENHO,ANKRD24,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,SLC30A3,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_200 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.77E-04 8.59E-01 8.57E-04 7.77E-03 32 160 "AMPH,ADAM23,CDH2,COL9A1,CRMP1,CRYM,PPP1R16B,CTH,SPOCK2,SNAP91,DUSP9,EYA1,SPSB4,PRELID3A,TVP23A,CHL1,GALC,FAM19A2,FAM107A,HAS2,PCDH8,PRTG,GAL3ST4,SALL1,MAPK12,CSRNP3,ANKRD6,SLC9A5,CLSTN2,ASXL3,CA14,NETO2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K3 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.79E-04 8.71E-01 8.67E-04 7.86E-03 43 238 "EMILIN3,AMPD2,IGDCC4,CACNA1G,GPC2,CACNA2D1,CDO1,PCYT1B,COL9A3,CLIP3,SNCAIP,DGKG,ACOT8,ELN,FDFT1,BAIAP2,ZMYND15,NBEA,HIGD1B,ZNF276,RAB30,HLF,IGF1,KHK,SMAD9,N6AMT1,TCEAL5,NFIX,NPY,CNTN3,PDE4D,PFKFB2,DIRAS2,ACSS3,DGLUCY,CNKSR2,DZIP1,ARHGAP26,ARHGEF9,ADGRL3,PHF24,HIF3A,STXBP4" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k1_200 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.84E-04 8.91E-01 8.86E-04 8.04E-03 14 47 "FMNL2,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,KITLG,TNFRSF19,STUM,SLC4A3,KDM3A,ACTR6" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k1 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.85E-04 8.96E-01 8.91E-04 8.07E-03 26 120 "ADORA1,PDE8B,BMP7,CALB1,CRLF1,COL9A3,IPCEF1,CNTNAP2,EMX2,SPSB4,FGF12,RASL10A,MAP7D2,L1CAM,KITLG,VWA2,MAPK4,LAMA1,RASGRF2,RET,SCN8A,FHOD3,TMEM150C,WSCD1,RPRM,VSNL1" Coexpression Atlas ratio_SC_vs_ECTO_1000_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 1.86E-04 9.03E-01 8.97E-04 8.13E-03 29 140 "ADCY5,SPARCL1,ZFYVE28,PLA2G4C,ATP1A3,AZGP1,LDHD,RUNX1T1,LDB2,CRYM,FAM78B,HSPA12B,ALDH1L1,GNAO1,NEGR1,ITGAM,MT1M,MX1,TMEM38A,FXYD1,PLTP,SGSM1,SSTR1,SYN2,TEK,TIMP4,RASD2,VIPR2,SLC30A3" Coexpression Atlas GSM399394_500 "alpha beta T cells, T.DP69+.Th, 4+ 8+ TCRlo/int 69+, Thymus, avg-3" "Immgen.org, GSE15907" 1.87E-04 9.10E-01 9.03E-04 8.18E-03 52 305 "ADCY6,AXIN2,ARHGAP20,PITPNM2,ARNTL,RASL11B,ALDH7A1,CLDN10,METTL6,CBARP,CNN3,LRIG1,CSNK1E,PPP1R16B,RASGRP1,TNK2,TMEM35A,FGF13,MEX3B,IP6K2,TMEM107,FYN,CHL1,RAPGEF6,KDM2B,KCNMB4,DCLK2,GSN,ADAMTS6,TOX2,BACH2,IL6ST,ITPKB,HECTD2,AQP11,ZNF827,PDE4D,BEND5,SATB1,HSPA4L,SH3BP2,FAM102A,PPM1E,ST6GAL1,DZIP1,ST8SIA1,TET1,SLC37A2,TNS1,TRIO,TTC3,MAP3K12" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.89E-04 9.16E-01 9.07E-04 8.22E-03 20 82 "APOC1,CDC14B,PLXNC1,FAM198B,AFF2,ZMAT1,GATM,ADGRA3,GPR37,RABL2A,MOV10,MXI1,ETFRF1,PRKCB,RPS6KA2,SYNE2,OBSL1,TST,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k3 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.89E-04 9.16E-01 9.07E-04 8.22E-03 20 82 "LRCH2,APAF1,TNRC6C,CACNA2D1,MRVI1,SYNCRIP,FREM1,RAB40B,CACFD1,NEGR1,MEF2C,MMP16,ZHX3,NEK4,RHBDL3,ZFPM2,TLR4,PLSCR4,FAM13C,SOCS4" Coexpression Atlas ratio_SC_vs_DE_500_K2 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 1.92E-04 9.30E-01 9.20E-04 8.34E-03 19 76 "PLA2G4C,ATP1A3,AZGP1,LDHD,CA4,CABP1,CPLX2,ALDH1L1,CCDC184,FRMD3,INSYN1,ITGAM,FXYD1,SEPT4,PTPRN2,SUSD4,SYT5,LGI4,SLC30A3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.96E-04 9.52E-01 9.41E-04 8.53E-03 23 101 "BCHE,CBLN1,CLCN3,LRRC3B,REEP2,CEP78,CSDC2,SHISAL1,PRTG,NLGN3,MAGEL2,NKAIN4,RELN,PTPN13,CCDC40,BAALC,STK32B,SALL1,PKNOX2,SNRPN,PDZRN3,ZIC2,SLC38A1" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.96E-04 9.53E-01 9.41E-04 8.53E-03 31 154 "ALCAM,ARHGAP20,TMEM108,MYRF,RUNX1T1,CBLN1,VCAN,EDNRA,MRO,PLXNC1,EYA1,PTK2B,FLNC,AFF2,GATM,FREM1,PPARGC1A,GLI2,GUCY1A1,KLHL23,MAP2,PCDH18,PLTP,PTCH1,TMEM255A,ROBO2,SULF2,ADGRL3,ZFPM2,VSNL1,STOX2" Coexpression Atlas gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4 DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.98E-04 9.60E-01 9.47E-04 8.58E-03 46 261 "RALGAPA1,AP2A2,OGT,APC,EPB41L5,CASK,BMP7,SCAPER,LRRFIP1,CLCN3,COL4A5,RBM39,VCAN,DDX46,HIPK3,SEMA3D,EIF5,EIF1,VPS13B,SUCO,ANKFY1,RAPGEF6,IQGAP2,PPARGC1A,GRB10,ICA1,KIF2A,LIFR,CHIC1,MKLN1,PIK3C2A,STRN3,KANSL1,DPF2,REV3L,NAPB,MYCBP2,STX1A,PRRC2C,DNMBP,MGRN1,OBSL1,ERCC6L2,RGMB,SSBP2,DOCK8" Coexpression Atlas GSM538343_500 "B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1" "Immgen.org, GSE15907" 1.98E-04 9.62E-01 9.48E-04 8.59E-03 65 405 "FMNL2,ZNF608,MTUS1,OSBPL1A,ABCD2,ATP1A3,BLM,ST3GAL5,PRC1,LY86,CNN3,GDA,CSF1R,CYBB,ARHGAP32,EBF1,SNX29,SEMA3D,RASA4,CALCRL,PAN3,GPHN,IGSF6,TLR7,SIRPB1,EYA1,F5,CHST15,SMC2,GATM,GCNT2,HP,ICA1,IRF8,IL12A,ITGAM,KIT,STMN1,LIFR,ASPRV1,MEF2C,MEIS1,MN1,MYCN,MYO5A,P2RY13,PILRA,RNASEL,ATP8B4,LRRK2,SATB1,BTBD3,TET1,SSTR2,RGL1,ANKRD28,TCF4,DMXL2,SYNE1,CYB561A3,CBX5,BHLHB9,TNS1,STXBP4,SSBP2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k1 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.99E-04 9.68E-01 9.52E-04 8.63E-03 25 114 "HECW2,RNF182,LDLRAD4,RUNX1T1,RCBTB2,HAPLN1,BRINP1,ETV1,TMEM132C,CORO2B,FOXF2,SPECC1,MEGF10,PCDH17,NEGR1,IFI16,NDP,PCDH18,ZFHX4,C12orf49,TRA2B,LIMCH1,TMPO,TRO,RPRM" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_500 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.00E-04 9.69E-01 9.52E-04 8.63E-03 32 161 "AXIN2,OGT,LGR5,SEMA4G,PDE8B,INSYN2B,DOCK2,RASGRP1,NRN1,SESN1,FAM69A,LAYN,NEXMIF,NPR2,ENPP2,MAPK9,GDPD1,GDPD2,CNTLN,RNASEL,SEMA6D,PRCD,TNFRSF19,STUM,KDM3A,ARHGAP26,ADAMTS17,TCF12,DCBLD1,LYPD6,TMEM178A,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.06E-04 9.98E-01 9.80E-04 8.88E-03 15 53 "DPP10,RUNX1T1,FAM171B,JAKMIP2,EGFR,TMEM132C,FOXF2,GRIA2,NDP,NEFM,CLDN11,TRHDE,ZFHX4,SALL1,PCDHB7" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500_k5 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.06E-04 9.98E-01 9.80E-04 8.88E-03 15 53 "PCDH19,DOC2A,BMP7,KIAA0040,GREB1,DUSP9,SPSB4,PLXNB1,LAMA1,NKAIN1,FAM184A,EMID1,TMEM150C,CA14,TMEM178A" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.11E-04 1.00E+00 1.01E-03 9.11E-03 10 27 "CNTFR,CRMP1,EDNRB,GFRA2,TAGLN3,NELL2,SLC10A4,RGS4,SYP,UCHL1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.16E-04 1.00E+00 1.03E-03 9.30E-03 12 37 "ADAM23,NRP2,CACNA2D1,MFAP3L,CPEB2,PDLIM5,IL6ST,ZHX3,SYN2,SYNPO2,FAM13C,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_500 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.16E-04 1.00E+00 1.03E-03 9.30E-03 66 414 "RALGAPA1,KLHL32,ADORA1,USP31,DOC2A,SEMA7A,EPB41L5,BMP7,CA4,THSD7A,HIP1R,ARHGAP24,AIF1L,TMCC2,OPTN,EIF5,SRPK3,CALCRL,RASGRP2,EPHB1,ST3GAL6,MED12L,CGREF1,GALC,IQGAP2,IGSF5,PCDH17,GGT5,AIFM3,PARD3B,SYNPO,HP,KCNJ16,LMO2,CLEC18A,MAPT,LYRM9,NCF2,SERPINI1,PIK3C2A,RETREG1,SCHIP1,MBOAT7,KANSL1,RELN,PTPRO,RIPOR1,FAM184A,DUSP15,REV3L,ROBO2,SALL1,ANKRD6,MYCBP2,DDN,STX1A,TMEM150C,PDLIM2,MGRN1,WSCD1,HEY1,ERCC6L2,RGMB,SSBP2,TMEM178A,MSRB3" Coexpression Atlas PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05 Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.16E-04 1.00E+00 1.03E-03 9.30E-03 161 1197 "KCNH8,SYS1,ADCY6,ZNF608,PCDH10,APC,GAS7,APOC1,LGR5,IGDCC4,ARHGDIG,ARRB1,ARSE,ZSCAN18,ZBTB10,CFLAR,BMP7,ST3GAL5,C5,MYRF,BAIAP3,CFAP410,USP2,ENTPD6,CDH2,LRRFIP1,CCPG1,CBARP,SOCS6,PLEKHB1,PPT2,CLTB,COL4A5,COL9A3,MAGED1,GAL3ST1,ENTPD4,CST3,PPP1R16B,PLCXD3,GREB1,ARHGEF4,GPSM1,MYADM,ARHGAP24,LONRF1,TBC1D5,DAPK3,B3GAT3,LYPD1,DTNA,EDNRA,HSD17B14,RCAN2,ERBB4,RASL12,RRAGB,FGFR3,AMOTL2,RGPD5,FLNC,CAMKK2,BRSK1,DENND2A,GALC,FREM1,MRPS31P5,GNAL,FERMT2,GPR37,TMEM121B,FAM222A,RASSF8,HAS2,MAN1B1,IL6ST,C2CD4C,ITPKB,KCNF1,KIFC3,KIT,LIFR,MAN2A2,MATN3,NRBP2,MXI1,MYO6,NBL1,NFE2L2,NRCAM,CLDN11,PALM,PRTG,ZDHHC8,PKM,GPSM2,PLCD1,JAKMIP1,SMOX,LRP12,PPP3CC,PRKAB2,RASGEF1B,SLC26A11,GDPD1,RELN,LAMA1,ELOVL2,CASTOR1,RIPOR1,FAM184A,LGI2,C12orf49,TCP11L1,EMID1,PLPPR3,ATAT1,CLIP1,MAPK12,SEMA6D,ATXN7,TNFRSF19,GALNT10,SH3BGR,R3HDM2,CCDC92,ANKRD6,NBPF1,RADIL,SMARCD3,RCOR3,LMBRD1,SPATA7,PEG10,DBNDD2,MCF2L2,ST5,SULF2,TMEM150C,DNMBP,FAM189A1,GPR161,GALNT17,PIK3R5,RGMB,TRO,TRPM2,DCBLD1,TTC3,RPRM,VLDLR,KCNK12,NDRG4,ANKS1B,MEIS3,ADAMTS9,PCBP4,MPPE1,SNX14,NETO2,SRGAP2B" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k1_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.17E-04 1.00E+00 1.03E-03 9.33E-03 21 89 "CALB1,CHGB,SOCS6,HAPLN1,DOCK4,ZNF804A,EDIL3,EMX2,MEX3B,FAM19A2,GPR85,PTX3,RFX3,ROBO2,PREX2,ZKSCAN3,RGL1,KLHL4,ACTR6,ASXL3,PCDH20" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_k4_1000 kidney_adult_RenCorpuscGlomer_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.17E-04 1.00E+00 1.03E-03 9.33E-03 30 148 "APBB2,PDE8B,CACNA2D1,ARHGEF6,KIAA0040,DGKB,EBF1,FRY,RCAN2,RASGRP2,GUCY1A1,GUCY1B1,FRMD3,INPP5B,LAYN,NCF2,PDE3A,SERPINI1,PIK3R1,PLCL1,SEPT4,PKIA,PTN,ZDHHC14,ZMAT4,PREX2,SLC12A2,ITPRID2,RGL1,TLR4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.20E-04 1.00E+00 1.04E-03 9.43E-03 48 277 "KDM5D,USP31,SORCS2,ALCAM,DPP10,CACNA1B,CERS5,USP6NL,GAPVD1,SPOCK2,GRIN3A,RCAN1,EDN1,FEM1B,AASS,FGF13,MEGF11,GGT5,PPARGC1A,GPD2,SOX21,FRMD5,AGFG1,ASPRV1,MARK1,OXTR,SMIM7,MAPK10,GRAMD1C,DIRAS2,RBBP8,ARMH4,HUNK,SATB1,KIF16B,PEX26,CXXC4,KIF13A,PDZRN3,ARC,HIF3A,ZMAT3,TIAM1,CHST5,SGK3,FZD3,PHTF2,RNF146" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_200 DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.25E-04 1.00E+00 1.06E-03 9.62E-03 32 162 "DOC2A,BMP7,CA4,GREB1,DUSP9,EPHB1,ST3GAL6,GALC,IGSF5,PCDH17,AIFM3,HP,CLEC18A,NRCAM,OXTR,RETREG1,MBOAT7,MAPK4,LAMA1,PTPRO,EMID1,SALL1,SCN8A,FHOD3,FAM81A,DDN,APOM,STX1A,TMEM150C,WSCD1,ERCC6L2,TMEM178A" Coexpression Atlas GSM476663_100 "Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1" "Immgen.org, GSE15907" 2.25E-04 1.00E+00 1.06E-03 9.63E-03 20 83 "GDA,CYBB,ARHGAP32,DGKG,PLXNC1,EYA1,MED12L,GCNT2,GRB10,GUCY1A1,HLF,ICA1,KIT,LMO2,MEIS1,MYCN,OCRL,TET1,TEK,TNS1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_200 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.27E-04 1.00E+00 1.07E-03 9.68E-03 34 176 "PPP4R4,TMEM108,CALB1,CBLN1,DCLK1,HAPLN1,VCAN,PLXNA4,DOCK4,SCRN1,DRP2,EDNRA,PLXNC1,EMX2,FLNC,FREM1,PPARGC1A,GPR37,GUCY1A1,KCND2,KLHL23,MATN2,MEIS1,NEFM,SERPINI1,PCDH18,RASGEF1B,ROBO2,UHRF1BP1L,ADGRL3,ZFPM2,ACTR6,WNK3,DPF3" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K1 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K1 Gudmap RNAseq 2.27E-04 1.00E+00 1.07E-03 9.68E-03 34 176 "C1QTNF1,NRP2,UBE2L6,ARHGEF6,DGKB,ZNF804A,EBF1,EDN1,HEYL,TLR7,RASL12,FCGRT,KHDRBS3,TPPP3,HIGD1B,GDF9,LOXL3,GUCY1A1,GUCY1B1,HLF,IFI16,IL6R,MX1,PLCB2,PLCL1,FXYD1,PTN,ZMAT4,RGS4,NKAIN2,TNS2,TLR4,PLSCR4,FAM13C" Coexpression Atlas GSM538258_500 "Myeloid Cells, DC.8+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-2" "Immgen.org, GSE15907" 2.28E-04 1.00E+00 1.08E-03 9.74E-03 65 407 "FMNL2,RNF150,ADRB2,ALCAM,FGD2,ADAM23,ST3GAL5,CD86,SCARB1,ARHGAP22,LY86,FAM149A,ZNF385A,CDC42BPB,CSF2RA,CST3,CYBB,DOCK4,HDAC9,DBN1,ARRDC4,PLXNC1,RASA4,PLEKHA1,IGSF6,FCGRT,OLFM1,FLT1,GATM,RAB30,MAP4K5,IRF8,LRRC25,JAK2,KIT,LIFR,ASPRV1,ADAM11,MYO9A,NUCB2,PDE1B,PFKFB3,PRKAB2,RASGEF1B,MARCH1,PID1,C1orf54,ROGDI,SNX22,LRRK2,KCNIP3,RTN1,MRAS,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,FNBP1,RGL1,SULF2,SEPT3,ADGRL3,CYB561A3,TRPM2,PLD4" Coexpression Atlas gudmap_developingGonad_P2_ovary_500_k2 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.29E-04 1.00E+00 1.08E-03 9.75E-03 17 65 "PKP4,BACH1,RBM39,EIF4G1,EPB41L2,LPAR4,CHIC1,MMP16,PDPK1,TMLHE,SLC12A2,ZC3H13,SYNE2,CBX5,SSBP2,ADAMTS9,GAN" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k2_200 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.29E-04 1.00E+00 1.08E-03 9.75E-03 17 65 "LCORL,BACH1,RUNX1T1,SLIT2,RBM39,TCAF1,EDNRA,EIF4G1,EMX2,SMC2,LPAR4,CHIC1,MEIS2,TMEM255A,TMLHE,CBX5,SSBP2" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k1_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.33E-04 1.00E+00 1.09E-03 9.90E-03 28 135 "SPARCL1,SEMA6A,BIN1,LCORL,APAF1,UPRT,SPAG9,LDB2,ZNF521,DLC1,CHST15,ST6GALNAC3,ZDHHC15,IGF1,MEST,LAYN,PALM,GNG2,SEMA6D,PEG10,ZNF423,RGL1,ARHGEF9,TCF4,ZEB1,TUBB2A,ZNF711,STOX2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.37E-04 1.00E+00 1.11E-03 1.01E-02 54 323 "ABR,AP2A2,ALCAM,LRCH2,ADGRB2,MYRF,ISPD,CDH2,MAGI1,RCBTB2,SLIT2,CREM,HAPLN1,BRINP1,DDX46,FARSB,EDIL3,WDPCP,SEMA3D,STARD3NL,EPHB1,CORO2B,FLT1,SPECC1,GABRA3,GABRB3,LOXL3,GPT2,FUT10,GPR37,GRIN2C,RASSF8,MEIS2,SAMD5,MYO6,HNRNPM,OPA1,PCDH18,MAGEL2,GRAMD1C,LRFN5,SEPHS1,SNCA,UNC5B,SPART,THSD1,NEK4,HIF3A,ZFPM2,ITGB3BP,TRO,INTS3,STOX2,NETO1" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_1000_k1 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.39E-04 1.00E+00 1.12E-03 1.02E-02 39 212 "ADORA1,PCDH19,DOC2A,EPB41L5,CDC14B,BMP7,KIAA0040,GREB1,SCRN1,DUSP9,HEYL,RASGRP2,CD320,ST3GAL6,FGFR1,FOXO3,IGSF5,CBX1,KCNMB4,ADGRA3,GPER1,FAM107A,KCNJ5,CLEC18A,OXTR,PLXNB1,ANKRD16,POLG,NKAIN1,EMID1,SALL1,HES6,ZNF821,DHX30,SLC9A5,TAF9,HEY1,ELP5,CA14" Coexpression Atlas GSM605868_500 "Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4" "Immgen.org, GSE15907" 2.45E-04 1.00E+00 1.15E-03 1.04E-02 65 408 "MTUS1,ALCAM,ABCD2,FGD2,APOC2,CASK,ATP1A3,ADAM15,BACH1,SCARB1,UBE2L6,LY86,GDA,CSF1R,CSF2RA,VCAN,CST3,CYBB,DOCK4,MYADM,DGKG,RASA4,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,OLFM1,FLT1,CAMKK2,TPPP3,GCNT2,ADAP1,IRAK3,HP,IFI16,LRRC25,IL6R,ITGAM,LIFR,MSR1,NCF2,PFKFB4,PLTP,PILRA,PTPRO,PID1,C1orf54,RTN1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,SNCA,SULF2,PLCB1,KIAA0930,TIAM1,TLR4,TRPS1,AMZ1,PLD4,NLRP3" Coexpression Atlas Arv_EB-LF_500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 2.45E-04 1.00E+00 1.15E-03 1.04E-02 45 256 "KCTD16,DPP10,MYRF,CALB2,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,SNAP91,DPP6,EDIL3,EDN3,TMEM132C,HPCAL4,CHL1,GFRA2,FREM1,CCDC184,STMN2,GRIA2,C1QL4,IGFBPL1,CELF5,C2orf72,TCEAL5,NNAT,NPY,NTRK2,PAX6,PCDH8,PDZRN4,MAGEL2,NKAIN4,PRPH,PTPRN,PTPRO,HUNK,TMEM200C,CLSTN2,SST,ZIC1,CRB2,DPYSL5" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_500 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.46E-04 1.00E+00 1.15E-03 1.04E-02 30 149 "TMEM108,MYRF,CALB1,CNTFR,ZNF521,CLIP3,DNM1,ABCA8,FLNC,TCEAL6,NKD1,KCND2,MATN2,MEIS1,MEIS2,MMP16,TCEAL5,NEFM,NNAT,PDE3A,PIK3R1,PCDH18,PTN,CCDC112,DZIP1,ZFPM2,ASXL3,TRPS1,FLRT2,PLEKHH2" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_nonFloorPlate_500 e8.5_NeuroEpith_nonFloorPlate_top-relative-expression-ranked_500 FaceBase_ST1 2.51E-04 1.00E+00 1.17E-03 1.06E-02 67 424 "BID,BMP7,CA4,CBLN1,SOCS6,LHX2,FAM19A5,SULT4A1,CNTFR,CNRIP1,CTH,IP6K1,JAKMIP2,FBXL5,GSDME,RAB39B,TSPAN5,EDN1,PHF20L1,PLEKHA1,PIPOX,REEP2,ARMCX1,CEP78,NOP56,PRELID3A,B4GALNT1,C15orf41,GATM,TOX3,LPAR4,PRDM5,RNF165,KAT7,FRMD5,ELOVL5,ICA1,METTL21A,IPO5,PACRG,AQP11,CHIC1,MYCN,PAX6,CYTL1,PCDH18,PMP22,ELOVL2,PEX2,DPF2,ELP2,ARMH4,ADAL,NCBP3,RMI1,MAPK12,SLC4A3,SPATA7,LHPP,MTCL1,WSCD1,DMXL2,TIMP4,TK2,PDSS2,ACTR3B,ZDHHC20" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_k2_1000 kidney_adult_RenCorpuscGlomer_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.52E-04 1.00E+00 1.17E-03 1.06E-02 41 227 "C1QTNF1,EPB41L5,APLP1,UPRT,TMEM108,THSD7A,SNCAIP,DOCK4,ARHGAP32,ARHGAP24,AIF1L,TSPAN5,OPTN,CEP85L,TLR7,ACSL4,CORO2B,ST3GAL6,ST6GALNAC3,GALC,IQGAP2,MALT1,PARD3B,RASSF8,SYNPO,MYO6,PDE4B,FA2H,PTH1R,PTPRO,RIPOR1,ROBO2,ST6GALNAC6,SLA,FAM81A,DDN,KANK1,TMEM150C,FRYL,SGK3,PLEKHH2" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.52E-04 1.00E+00 1.18E-03 1.07E-02 56 339 "RALGAPA1,ABCF1,OGT,PKP4,APC,PHYHD1,BMP7,CLCN3,RBM39,UBXN2A,ARHGAP24,DDX46,HIPK3,SEMA3D,EIF5,SRPK3,EIF1,MED12L,SUCO,SYNCRIP,SMC2,PDLIM5,IQGAP2,PPARGC1A,CNTRL,GRB10,ICA1,KITLG,NEK1,CNOT4,OCRL,PIK3C2A,PSAT1,MBOAT7,KANSL1,RASGRF2,DPF2,REV3L,CLIP1,LIMCH1,STX1A,PRRC2C,PJA1,DNMBP,TBL1X,MGRN1,NSD1,ERCC6L2,R3HDM1,RGMB,TRIO,SSBP2,VLDLR,ZNF23,ZNF24,FIP1L1" Coexpression Atlas GSM476672_500 "gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3" "Immgen.org, GSE15907" 2.54E-04 1.00E+00 1.18E-03 1.07E-02 63 393 "ACTN1,FMNL2,ADORA2A,PKP4,ATP1B3,BAIAP3,CD86,CD38,DGKI,CHN2,LY86,CSF1R,IPCEF1,CYBB,DOCK4,HDAC9,HDAC4,SPOCK2,PITPNC1,DMPK,HEYL,RASGRP1,PCOLCE2,IGSF6,TLR7,FCGR1A,FCGR3A,FCGRT,FGF13,FYN,TRAF3IP2,GATM,GFRA2,HPGDS,AGFG1,IGF1,LRRC25,KCNJ16,KIT,TTYH2,MYO9A,P2RY13,ZNF827,ABCB1,PILRA,SH3KBP1,PPP3CC,RASGEF1B,GDPD1,SEMA6D,SATB1,FAM102A,DZIP1,SLC11A1,SLC12A2,TET1,RGL1,ADGRL3,TLR4,TRIO,RUNDC3B,TRPM2,PLD4" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500_K2 facebase_RNAseq_e10.5_OlfacPit_2500_K2 Gudmap RNAseq 2.56E-04 1.00E+00 1.19E-03 1.08E-02 21 90 "ACHE,ADD2,NRP2,NRXN3,IGDCC3,ADGRV1,TPPP3,CCDC184,TOX2,FRMD3,MAP6,MAPT,SHC3,NCF2,SERPINI1,ZMAT4,RGS4,SNAP25,GALNT17,CA14,AP3B2" Coexpression Atlas GSM854332_500 "Myeloid Cells, Mo.6C-II-.BM, B220neg CD3neg CD115+ Ly-6C/Glo CD43+, Bone marrow, avg-3" "Immgen.org, GSE15907" 2.62E-04 1.00E+00 1.22E-03 1.11E-02 65 409 "ADRB2,MTUS1,ABCD2,FGD2,SUGT1P4-STRA6LP-CCDC180,APOC2,ATP1A3,ST3GAL5,RAB29,SCARB1,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,GALNT9,CST3,CYBB,MYADM,DGKG,DBI,RCAN1,TOM1,EBI3,RASA4,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,PCYOX1,TPPP3,IP6K3,GCNT2,ADAP1,SLC2A6,IRAK3,PADI2,HP,IRF8,LRRC25,IL6R,ITGAM,L1CAM,STMN1,LMO2,PIK3AP1,NCF2,PFKFB4,PLTP,PILRA,MAPK3,PID1,C1orf54,RPS6KA2,ST6GALNAC6,RTN1,SH3BP2,SLC11A1,ELMO2,KIAA0930,LAT2,PLD4,NLRP3" Coexpression Atlas JC_hmvEC_2500_K1 JC_hmvEC_top-relative-expression-ranked_2500_k-means-cluster#1 PCBC 2.64E-04 1.00E+00 1.23E-03 1.11E-02 130 939 "CCDC85A,TMCC3,MTUS1,HECW2,KIAA1324,ADGRF5,SRPX,PLA2G4C,MARCH3,INSYN2B,CFLAR,SYNJ2,CASTOR3,CACNA2D1,THSD7A,CH25H,LDB2,CDC25B,CFL2,ARHGAP22,C7orf61,CNN3,IQCK,ABI3BP,AKAP12,SNCAIP,CSF1,OSBPL3,PLXNA4,PPP1R16B,DOCK4,SNPH,ARHGAP24,KLHL3,CPEB2,DRP2,PDCD6IP,MAMLD1,TSPAN5,EDN1,FRY,RGS17,CALCRL,SLC43A2,NRN1,ST3GAL6,CHST15,FCGRT,SCARA3,FLT1,DCTN2,TPK1,KHDRBS3,ST6GALNAC3,SULT1C4,GGT5,GHR,LYVE1,PRUNE2,C1QL4,PARD3B,ADAMTS6,SLC2A6,TNFAIP8L3,NEGR1,MYLK2,IL6ST,TMEM240,INPP1,SLC6A17,ITPKB,LAMP2,SMAD1,MSR1,LYRM9,LAYN,RTL5,NBL1,NOVA2,NRCAM,CLDN11,PDE4B,TMOD2,NALCN,MAPK3,RELN,SNRK,PTPRB,PTPRE,PTPRN2,PTX3,FAT4,RASGRF2,ZDHHC14,CRTAC1,RGS3,RGS4,ZFHX4,RPS6KA2,HSD11B1L,PEAR1,SEC14L1,SGK1,ST6GAL1,ABLIM3,THSD1,KLHL4,TCF4,ZEB1,PCDHGA11,PCDHGA4,DOCK9,SLC35G2,TEK,TLR4,TRIO,DCBLD1,FLRT2,AGMO,ZBTB38,SLC30A3,SLC30A4,GDPD5,NAV3,PLSCR4,RTN4,GJC2,ADAMTSL3,RSPRY1,NHSL1" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500_k3 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.67E-04 1.00E+00 1.24E-03 1.12E-02 23 103 "PI16,ADAM23,GPR146,CACNA2D1,ENTPD2,OSBPL3,MFAP3L,CHRDL1,HIPK3,PCOLCE2,MRVI1,NRN1,GCNT2,HLF,KCNF1,MBP,RGS4,SCN7A,SYN2,RGMB,AGMO,PLSCR4,FAM13C" Coexpression Atlas GSM605787_500 "gamma delta T cells, Tgd.vg2+.Sp, TCRd+ Vg2+ CD44-, Spleen, avg-3" "Immgen.org, GSE15907" 2.68E-04 1.00E+00 1.24E-03 1.13E-02 62 386 "ACTN1,NDRG2,ADD1,AXIN2,ESYT2,ATP1B3,BAIAP3,LDLRAD4,CLDN10,CHN2,IPCEF1,HDAC9,RIPOR2,HDAC4,SPOCK2,PITPNC1,RASGRP1,RASGRP2,KAT8,FGF13,MEX3B,SARAF,TRAF3IP2,B4GALNT1,RAPGEF6,SESN1,PADI2,BACH2,ZDHHC15,AGFG1,IL6ST,ITPKB,KIT,HECTD2,P2RX7,ZNF827,PDE4D,ABCB1,SERPINI1,JAKMIP1,SLC25A23,SH3KBP1,CEP97,BEND5,TSPY26P,SATB1,RASA3,FAM102A,ST6GAL1,DZIP1,ST8SIA1,SLC14A1,TET1,SP4,DNAJC9,TCF12,TRIO,RUNDC3B,SSBP2,TTC3,UBE2H,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K4 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 2.69E-04 1.00E+00 1.25E-03 1.13E-02 42 235 "DGCR6,OSBPL1A,TBC1D14,GAS7,APOC2,CPNE5,ARRB2,TTLL9,ZNF599,CA12,ARHGEF1,SUMF2,CREM,CRY2,CRYM,ELN,NCALD,CDKL3,ST3GAL6,PPP1R1B,HPCAL4,ZMYND15,APOPT1,TPK1,FYB1,GPR155,MID1,NTRK3,ETFRF1,ENPP2,PILRA,CYBC1,DEF8,STRC,KCNIP3,SEMA6D,SH3BP2,TSPYL2,PDLIM2,IQCE,KLC2,LAMP5" Coexpression Atlas Arv_EB-LF_1000 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000 PCBC 2.70E-04 1.00E+00 1.25E-03 1.13E-02 136 990 "ELFN2,CCDC85A,TMCC3,BEND6,PCDH19,AGT,KCTD16,SORCS2,SYT13,PDZD4,DPP10,LRCH2,LGR5,INSYN2B,RNF182,MYRF,CALB2,CABP7,CAMK2A,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,CSF1R,LRRC3B,RIMS4,PHACTR3,CNTNAP2,CYBB,LYPD1,SNAP91,SPOCK3,DLX1,DPP6,EDIL3,EDN3,SEMA3D,LRRC17,ADGRV1,CLVS1,TMEM132C,FCGR3A,HPCAL4,PSD2,MEGF10,GABRA3,CHL1,GALNT15,IP6K3,SRRM4,CPLX2,GFRA2,FREM1,CSDC2,CCDC184,STMN2,GRIA2,C1QL4,GUCY1A1,UBE2QL1,BACH2,VSIG4,IGFBPL1,SHISA6,CELF5,C2orf72,IGF1,KIAA1755,SLC6A17,INSM1,CDH20,CLEC18A,MAPT,LAYN,TCEAL5,NNAT,NPY,NTRK2,OXTR,PAX6,PCDH8,CYTL1,PDZRN4,TRHDE,SDK2,NECAB2,MAGEL2,NKAIN4,SMIM10L2B,PRPH,RELN,KLK6,PSD,LAMA1,PTH1R,ELOVL2,PTPRN,PTPRO,TMEM255A,RGS4,ZFHX4,HUNK,KCNIP1,RTN1,LRFN5,TNFRSF19,TMEM200C,HKDC1,PKNOX2,TRIM67,SLC11A1,DMRTC1,SNAP25,SPP1,CLSTN2,SST,SYT5,PCDHGC5,PCDHGB6,ASXL3,RIMBP2,DOK6,SYNPO2,LINC00511,ZIC1,KCNT2,CRB2,REEP1,DPYSL5,GAL3ST3,DNAH10,FAM13C,TMEM63C,JPH3" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 2.72E-04 1.00E+00 1.26E-03 1.14E-02 51 302 "ALCAM,TMEM108,CA4,CBLN1,CLCN3,LRRC3B,FAM169A,HDAC9,MYADM,ARHGAP24,WDR20,CHRDL1,PLEKHA1,PIPOX,REEP2,FGF11,SYT3,GFRA2,CSDC2,GPD2,LPAR4,LINGO1,HMGCL,TCEAL6,CDH20,KHK,IPO5,AQP11,MATN2,IGSF11,PRTG,SNX10,ZFYVE21,PKM,MAGEL2,NKAIN4,PTPN13,TSPY26P,FIGN,STK32B,EMID1,SALL1,MAPK12,SNRPN,PDZRN3,PBLD,ADAMTS17,MTCL1,BEX4,ZIC2,SLC38A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.72E-04 1.00E+00 1.26E-03 1.14E-02 16 60 "DPP10,CADPS,DCLK1,FAM171B,CRYM,JAKMIP2,GRIN3A,EYA1,FGF13,UBE2E3,INSM1,NDP,CLDN11,CNTN3,GPR85,TRHDE" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k3_500 kidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.79E-04 1.00E+00 1.29E-03 1.17E-02 26 123 "RNF157,MTUS1,ALCAM,AMPH,ADAM23,CACNB4,CDH2,CLIP3,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,EYA1,FGFR1,SCARA3,TDRKH,FAM107A,HAS2,NEGR1,NME4,CNTN3,SALL1,TRIM2,PCDHB9,LAMP5" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k4_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.79E-04 1.00E+00 1.29E-03 1.17E-02 26 123 "RNF182,CHGB,COL9A1,GSDME,EIF4G1,CHST15,PRMT5,MEX3B,FAM19A2,INSM1,MYCN,NEFM,LRRN3,DIRAS2,ROBO2,ZKSCAN3,SNRPN,RBM26,RGL1,SULF2,KLHL4,CLASP1,HEY1,ASXL3,TPM1,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k2 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.81E-04 1.00E+00 1.29E-03 1.17E-02 31 157 "MYOM1,CFL2,AKAP5,PRKAG2,FERMT2,PRUNE2,BVES,HNMT,SHISAL1,IL6ST,KCNB1,MMP17,MYH3,ALDH1L2,NPTX2,TMEM38A,SCHIP1,PRKCB,PSD,RYR3,STUM,SH3BGR,FHOD3,ABLIM3,FNBP1,DBNDD2,ARHGEF9,ENHO,PPIL6,RBFOX3,ACTR3B" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k5 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.83E-04 1.00E+00 1.30E-03 1.18E-02 32 164 "ADGRF5,ARRB1,NRP2,CA8,CD38,LY86,ELMO1,FAM107B,EPHB1,FLT1,FYB1,PCDH17,GGTA1P,NCKAP1L,IRF8,IGF1,TM6SF1,MSR1,NCF2,NRCAM,GNG2,PTPRB,LIMCH1,SAMSN1,THSD1,TAL1,KLHL4,TEK,TLR4,NPL,WIPF1,RGS7BP" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.84E-04 1.00E+00 1.30E-03 1.18E-02 22 97 "ARHGAP20,IGDCC4,CALB1,CDON,IP6K2,TRAF3IP2,RAB30,KCND2,MAP2,MATN2,MEIS1,PIK3R1,PCDH18,LRRN3,REV3L,HUNK,FAIM2,PEG10,ADGRL3,ZFPM2,TRPS1,PLEKHH2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_100 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100 FaceBase_RNAseq 2.84E-04 1.00E+00 1.30E-03 1.18E-02 22 97 "USP31,GPRASP2,APOC1,MADD,BARD1,LDLRAD4,CACNA1A,HAP1,CNTFR,CSF2RA,ACOT8,APC2,LOXL3,HLF,IGF1,L1CAM,PAX6,PRRT2,PLCB1,PHF24,UCHL1,SENP7" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k1_1000 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.91E-04 1.00E+00 1.34E-03 1.21E-02 27 130 "PWWP2A,KLHL13,RNF182,FUBP1,RUNX1T1,HAPLN1,GSDME,ALKBH8,EDIL3,CHST15,PRMT5,MEX3B,FAM19A2,INSM1,MYCN,NEFM,TMEM255A,ZFHX4,ROBO2,CSRNP3,ZKSCAN3,RBM26,RGL1,KLHL4,CLASP1,ASXL3,TPM1" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k3_500 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.98E-04 1.00E+00 1.37E-03 1.24E-02 10 28 "BACH1,MYRF,DBN1,GSDME,LPAR4,NNAT,SNRPN,RBM26,KLHL4,PCBP4" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_100_k2 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.98E-04 1.00E+00 1.37E-03 1.24E-02 10 28 "BACH1,RUNX1T1,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,FLRT2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k4 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.01E-04 1.00E+00 1.37E-03 1.25E-02 21 91 "ADCY5,ATP2A2,CACNA2D1,AKAP6,CPEB2,DTNA,NCALD,MRVI1,FHL1,KCNF1,MBP,PDE4D,PRKCB,SCN7A,SYN2,NACC2,SYNPO2,PLSCR4,RGS7BP,FAM13C,MSRB3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.01E-04 1.00E+00 1.37E-03 1.25E-02 21 91 "PCDH10,CADPS,DCLK1,CHGB,EYA1,TMEM132C,FOXF2,STMN2,IFI16,MAP4,MYH3,NEFM,CLDN11,GPR85,TRHDE,MAPK10,PRPH,RGS4,ZFHX4,CSRNP3,SNAP25" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K3 facebase_RNAseq_e10.5_Emin_MedNas_2500_K3 Gudmap RNAseq 3.01E-04 1.00E+00 1.37E-03 1.25E-02 21 91 "ACHE,ADD2,NRXN3,QKI,ZNF804A,EDNRB,MRVI1,HIGD1B,TUBA8,NTNG2,GPR12,GUCY1B1,KCNJ5,MAPT,SHC3,NTRK2,ABCB1,SERPINI1,PLCB2,CABCOCO1,GALNT17" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.09E-04 1.00E+00 1.41E-03 1.28E-02 23 104 "KDM5D,CDH2,SCRN1,MRO,PLXNC1,ERBB2,FAM198B,PTK2B,AFF2,PPARGC1A,ADGRA3,GPR37,PRKCB,PTCH1,ROBO1,GLDN,RPS6KA2,MRAS,ST6GAL1,SPP1,SYNE2,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_500_k2 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.12E-04 1.00E+00 1.42E-03 1.29E-02 35 186 "KLHL32,SEMA7A,EPB41L5,THSD7A,HIP1R,ARHGAP24,AIF1L,TMCC2,OPTN,SRPK3,ST3GAL6,CGREF1,IQGAP2,IGSF5,GGT5,PARD3B,SYNPO,HP,MAPT,LYRM9,SERPINI1,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,FAM184A,DUSP15,ROBO2,ANKRD6,DDN,STX1A,TMEM150C,PDLIM2,TMEM178A" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_1000 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 3.13E-04 1.00E+00 1.42E-03 1.29E-02 135 985 "KLHL32,OSBPL8,PHF12,ARRB2,ZBTB10,NUMB,TTLL9,BACH1,BBS2,MPDZ,SEC11C,BLM,ZNF599,BMPR1B,CA12,LRBA,CDC25B,LRWD1,TBRG4,SRSF11,CNOT8,LHX2,PPT2,PCYT1B,COL9A1,IGDCC3,HAPLN1,CSNK1G3,SIPA1L1,PPP1R16B,GREB1,RASSF2,KIAA0586,AIF1L,DLX1,DTNB,DUSP9,E2F5,KLHL5,YAF2,EIF5,COQ7,SRRM1,RRAGB,CELF1,OGA,NEURL4,MTHFD2,C15orf41,USP19,TXNL4A,COPS8,RNPS1,DBF4,ADGRA3,ATOH8,TOX2,METTL21A,IPO5,PAXBP1,SMAD9,KITLG,MYCN,NNAT,PRTG,PDE4D,PDPK1,MAGEL2,KANSL1,PRODH,ZSCAN2,PPP2R3C,GAL3ST4,FIGN,KIF7,SETD5,GSTCD,BAALC,ST6GALNAC6,CLIP1,TRAPPC13,SALL1,SCP2,ZFP2,CASC3,GALNT10,KIF21A,CHD9,FNDC3A,FAM81A,SEPHS1,SLC12A2,SMARCA4,LIMCH1,SPATA7,UNC5B,LARP4,MPRIP,STAU1,STXBP1,ZC3H4,SYNE2,MMS19,TAF9,ALG1,TCEA1,USP22,DICER1,SIRT1,TMEM121,TIAM1,HEY1,BHLHB9,TP53BP1,AMACR,TRO,TRPS1,TSN,CA14,ZKSCAN5,BCL2L13,CLIP2,CLDND1,ZNF189,SLC38A1,ADAMTS9,URM1,PCBP4,KAT6A,HNRNPA3,PHTF2,ZDHHC20,FRMD6,DPF3,GAN" Coexpression Atlas gudmap_developingGonad_P2_ovary_500_k4 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.16E-04 1.00E+00 1.43E-03 1.30E-02 31 158 "PLA2G4C,ABI3BP,MYRIP,GDA,CSNK1E,PLXNA4,GSDME,SNAP91,SLC12A6,GDF9,SHISA6,KIT,SYTL4,SETD4,ABCB1,MAPK10,GDPD1,STK32A,SUSD4,KIF16B,CPEB3,SLC14A1,CLSTN2,CAMTA1,MTMR14,PARD3,TBC1D15,TRIM9,NDRG4,FAM47E,DPF3" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_100 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.16E-04 1.00E+00 1.43E-03 1.30E-02 20 85 "CDH2,COL9A1,CRMP1,CRYM,SPOCK2,SNAP91,EYA1,SPSB4,CHL1,GALC,FAM19A2,FAM107A,HAS2,PCDH8,PRTG,GAL3ST4,SALL1,MAPK12,CSRNP3,ANKRD6" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k2_1000 kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.16E-04 1.00E+00 1.43E-03 1.30E-02 20 85 "MTUS1,WDR35,TXNDC16,ALCAM,OGT,CASK,ADAM23,BCHE,IL33,SPOCK2,ARRDC4,EXTL2,EZH1,GLUL,MEIS2,NFIX,NPR2,PLTP,SULF2,TPM2" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_100 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.16E-04 1.00E+00 1.43E-03 1.30E-02 20 85 "DOC2A,CALB1,CRLF1,IPCEF1,CNTNAP2,CTH,DUSP9,EMX2,SPSB4,RASL10A,FRMD5,KCNJ16,L1CAM,VWA2,LAMA1,RASGRF2,RET,SCN8A,RPRM,VSNL1" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_200_k2 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.16E-04 1.00E+00 1.43E-03 1.30E-02 20 85 "THSD7A,TMCC2,OPTN,SRPK3,CGREF1,IQGAP2,IGSF5,PARD3B,HP,MAPT,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,DUSP15,DDN,STX1A,TMEM150C,TMEM178A" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_100 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.28E-04 1.00E+00 1.48E-03 1.35E-02 19 79 "LCORL,BACH1,RUNX1T1,RBM39,MEX3B,LPAR4,INSM1,CHIC1,MEIS2,NEFM,PCDH8,GPR85,TMLHE,MEG3,CSRNP3,KLHL4,CBX5,SSBP2,ADAMTS9" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.29E-04 1.00E+00 1.48E-03 1.35E-02 38 208 "ARHGAP20,MYRF,CACNA2D1,KALRN,CBLN1,LARGE1,SLIT2,CNTFR,CLIP3,VCAN,DNM1,TSPAN5,EDNRA,SEMA3D,FGFR1,FLNC,DENND2A,FREM1,GHR,GLI2,GUCY1A1,GUCY1B1,NKD1,MATN2,MEIS1,MEIS2,NEFM,NNAT,PDE3A,PCDH18,LAMA1,PTN,ROBO2,PKNOX2,ASXL3,TRPS1,PLEKHH2,ST8SIA2" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_bud_2500_K1 gudmap_RNAseq_e11.5_Ureteric_bud_2500_K1 Gudmap RNAseq 3.29E-04 1.00E+00 1.48E-03 1.35E-02 38 208 "HECW2,PITPNM2,ARHGEF7,SCARB1,ABCG2,CREM,PPP1R16B,CYBB,DOCK4,SLC43A2,IP6K3,LPAR4,ACOT7,KIT,SYTL4,NCOA7,SMAD1,TM6SF1,PALM,PDE4B,PTPRB,C1orf109,KCTD17,RPS6KA2,SEMA6D,HES6,BTBD3,LIMS2,LIMCH1,MCF2L,WSCD1,CHST8,HEY1,TUBB2A,REEP1,ADAMTS9,CIAPIN1,SPATA13" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_1000_k3 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.36E-04 1.00E+00 1.51E-03 1.37E-02 46 267 "RNF157,ADORA1,PCDH19,APBA2,EPB41L5,CAMK2B,GREB1,SV2B,USP3,HEYL,EIF1,EPHB1,RACK1,ST3GAL6,FKTN,SLC9B2,FGFR1,PSD2,TRIM16,IGSF5,ADGRA3,DIDO1,PRDM5,HP,KCNJ5,CLEC18A,MARK1,MAT2A,TM6SF1,NPY,OXTR,CNTN3,PDE1C,OLA1,POLG,NDUFS7,PTPN13,PTPRD,DUSP15,EMID1,SH3BGR,DHX30,BDP1,TAF9,HEY1,URM1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K5 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 3.36E-04 1.00E+00 1.51E-03 1.37E-02 37 201 "ADCY8,ALCAM,VAT1L,TTLL9,CA4,THSD7A,CBLN1,LRRC3B,FAM169A,GREB1,HDAC9,MYADM,ARHGAP24,WDR20,CERCAM,PIPOX,FGF11,CSDC2,HMGCL,TCEAL6,CDH20,KHK,MATN2,ADAM22,NLGN3,ZFYVE21,PPP3CC,NKAIN4,CCDC40,TSPY26P,FIGN,STK32B,EMID1,PDZRN3,PBLD,ADAMTS17,RBFOX3" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.36E-04 1.00E+00 1.51E-03 1.37E-02 18 73 "RUNX1T1,EBF1,SEMA3D,GFRA2,KCND2,MATN2,MEIS2,CLDN11,PCDH8,PIK3R1,PTPRD,FAT4,LGI2,MEG3,CSRNP3,MTERF2,TROVE2,ZFPM2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.36E-04 1.00E+00 1.51E-03 1.37E-02 113 802 "NCKAP5,KDM5D,PLEKHH1,USP31,SORCS2,ALCAM,PCDH10,DPP10,EPB41L5,USP37,INSYN2B,ZNF599,DST,LDLRAD4,CACNA1B,CH25H,CERS5,LRRFIP1,CNR1,PCYT1B,ABI3BP,MYRIP,SLC35F1,NCOR1,CNTNAP2,ARHGEF4,RIMS2,USP6NL,GAPVD1,LONRF1,SPOCK2,PITPNC1,DLX1,GRIN3A,DMD,RCAN1,EDN1,FEM1B,SEMA3D,KLHL5,AASS,NRN1,FGF13,FGFR3,UBE2E3,FOXF2,TRIM16,FUT9,MEGF11,CHL1,ADAM28,GGT5,PPARGC1A,TOX3,KIAA1958,LNX1,GPD2,SOX21,MAP4K5,FRMD5,AGFG1,ASPRV1,MARK1,MBP,VWA2,OXTR,PCDH8,GPR85,OLA1,SMIM7,PLXNB1,PPP2R2B,MAPK10,GRAMD1C,DIRAS2,GDPD1,PTPRD,SUSD4,RBBP8,RET,FIGN,C12orf49,ROBO1,ARMH4,RPS20,HUNK,CCDC112,SATB1,SH3BGR,KIF16B,ANKRD6,PEX26,CXXC4,KIF13A,PDZRN3,KLHL7,ARC,COBL,TRIM2,HIF3A,ZMAT3,AKTIP,TIAM1,CHST5,SYNPO2,SGK3,RPRM,UGT8,WNT7A,FZD3,PHTF2,NETO2,RNF146" Coexpression Atlas facebase_RNAseq_e9.5_MandArch_2500_K3 facebase_RNAseq_e9.5_MandArch_2500_K3 Gudmap RNAseq 3.38E-04 1.00E+00 1.52E-03 1.38E-02 167 1260 "ACTN1,KIAA1211,INTS2,PCDH19,OSBPL8,TRMT9B,AMPD2,AMPH,AMT,NT5C3B,TMEFF1,ARHGDIG,PTCH2,DPY19L3,BACH1,BLM,ZNF599,BMPR1B,WASF1,MYRF,CARS,LRBA,ARHGEF2,CDC25B,TBRG4,SRSF11,PPT2,FAM19A5,QKI,HOMER3,CNR1,AHCTF1,SMARCAL1,ZNF385A,HAPLN1,PLXNA4,PLCXD3,CTH,GREB1,GPSM1,INTS1,IP6K1,AIF1L,KIAA0753,POM121,SEC16A,DNM1,DMPK,DUSP9,E2F5,EIF4G1,USPL1,MFSD10,RABEPK,ERCC2,MRPL37,MRPL10,ETV1,EYA1,TBC1D16,CEP78,PRMT5,POLR1B,SPSB4,AMOTL2,MEX3B,FLNC,NELFCD,CINP,UFM1,FAM49B,RASL10A,ZNF605,PRELID3A,ST6GALNAC3,MTHFD2,SEPT9,AHDC1,FREM1,TCERG1,RNPS1,DBF4,GLYR1,GLUL,ADGRA3,GRB10,KAT7,ATOH8,IRAK3,AGFG1,HSF2,TJAP1,IBA57,METTL21A,SFXN5,SMAD9,MATK,GIT1,NME4,PCBP3,SLC11A2,CHAMP1,OGG1,PALM,CDK18,PDE4A,PDE4D,PDPK1,PKM,KCTD15,GPSM2,NLE1,PSAT1,PPP5C,RASGEF1B,MAPK7,PRODH,SPDL1,ZIK1,ZSCAN2,NKAIN1,ROGDI,FIGN,RFX3,KCTD17,NUDT11,RPS6KA2,ST6GALNAC6,SALL1,ZFP2,SH3BP2,MYO18A,SHMT2,ST6GAL1,CCDC92,DHX30,PKNOX2,ZNF334,LIMCH1,SOX11,ZSWIM8,CEP68,STX1A,SULF2,MMS19,DICER1,SIRT1,ZFPM2,C18orf54,HEY1,TRPS1,HIRA,UBE3A,USP1,CCDC14,KLC2,ZFP41,EML6,ZNF189,MEIS3,DHX33,SLC38A1,TUBA1A,ADAMTS9,URM1,PHTF2,FBXO36" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.39E-04 1.00E+00 1.52E-03 1.38E-02 17 67 "PCDH10,RUNX1T1,ANKRD44,HDAC9,EGFR,ETV1,EYA1,TMEM132C,FOXF2,MEGF10,IFI16,GPR85,PCDH18,TRHDE,ZFHX4,SALL1,CSRNP3" Coexpression Atlas gudmap_developingGonad_e12.5_testes_1000 DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.42E-04 1.00E+00 1.53E-03 1.39E-02 115 819 "ABCF1,ADD1,PWWP2A,AK2,TAOK1,AMH,OGT,SEMA7A,LCORL,EPB41L5,APLP1,CASK,ARHGDIG,NUMB,RNF182,BACH1,ADGRB2,ST3GAL5,MYRF,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,QKI,COL9A3,RBM39,RNF14,PUM1,ARHGAP32,MATR3,DAPK1,DAPK3,DBI,DBN1,DCTN1,GSDME,ALKBH8,RCAN1,DTNA,DNM1L,EDNRA,MBNL2,PLXNC1,EPB41L2,PTK2B,PRMT5,SEC24B,FGFR1,FYN,AHDC1,CSDC2,TCERG1,LPAR4,GPR37,GRB10,GUCY1B1,SMAP1,KIF2A,TTYH2,CHIC1,MEF2C,KITLG,MYO7A,NNAT,OLA1,SEMA5B,PIK3R1,ZNF655,PCDH18,PLTP,EXOSC10,SH3KBP1,PRKACB,PTPRD,PTPRE,TMEM255A,UBR7,ROBO2,MEG3,ATXN2,SUPT20H,ARX,SEC31A,ZKSCAN3,SMARCA4,SNRPN,RBM26,SPART,TROVE2,JMJD6,SYNE2,PJA1,FBXW11,KLHL4,SIN3B,PUM2,ASXL3,TMPO,TNS1,TPM1,NR2C2,KCNE5,SSBP2,TST,USP1,ZFAND5,INTS3,STOX2,ADAMTS9,PCBP4,RTN4,ADAMTS10" Coexpression Atlas gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_1000 dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.47E-04 1.00E+00 1.55E-03 1.41E-02 35 187 "AXIN2,BRAP,ESYT2,HACE1,HFM1,MADD,PLA2G4C,ZNF583,LRBA,LONRF2,C4orf33,DZIP3,DUSP9,DENND4A,PRKAG2,COQ10A,ADAM22,MYO9A,NEK1,PRTG,EML5,ZCWPW1,CARF,CCDC25,STX1B,FNIP1,KIF27,SH3BGR,CNKSR2,CCDC92,DOP1A,ZSCAN29,VPS13A,UGT8,SLC30A4" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_200 kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.47E-04 1.00E+00 1.56E-03 1.41E-02 29 145 "KLHL32,PCDH19,SEMA6A,PROM1,CALB1,B4GALT6,HAPLN1,FAM169A,PLEKHA1,EMX2,ACSL4,IGSF5,MAP7D2,HAS2,KIT,KITLG,PRTG,EML5,TMEM255A,RET,MORC4,NUDT11,PREX2,NUDT10,KLHL4,CUX2,BEX4,CA14,VSNL1" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO amniotic fluid MSC_cfr-2X-p05 ECTO blastocyst_vs_ECTO amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.50E-04 1.00E+00 1.57E-03 1.42E-02 49 290 "AXIN2,PCDH10,RASL11B,NRP2,LRBA,NOG,PLEKHB1,SLIT2,NGEF,IQCK,COL11A2,NRG2,HAPLN1,PDE4DIP,LYPD1,ARRDC4,EDNRA,EPHB1,TMEM132C,SCARA3,ERAP1,ITPKB,KIT,CLEC18A,MATN2,MEIS2,MPP2,DBNL,SAMD5,MYCN,TCEAL5,HNRNPM,NPY,PLEC,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,PRODH,RELN,GDPD2,ZFHX4,TNFRSF19,DOK5,IQCE,PCDHGA10,LMF1,DOCK8,IFT88" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000_k3 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.52E-04 1.00E+00 1.57E-03 1.43E-02 30 152 "RALGAPA1,OGT,EPB41L5,SLC4A4,CACNA2D1,CLCN3,OSBPL3,ARHGAP24,GOLT1B,EIF4G2,SYNCRIP,RAPGEF6,GHR,PPARGC1A,GRB10,PIK3C2A,RETREG1,KANSL1,BCAS3,REV3L,FAM126B,ZHX3,MYCBP2,PRRC2C,VPS13A,ERCC6L2,RGMB,TRIO,TRPS1,KLHDC1" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_1000_K5 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 3.53E-04 1.00E+00 1.57E-03 1.43E-02 21 92 "MPDZ,BMPR1B,CDC25B,SRSF11,LHX2,SIPA1L1,RASSF2,DLX1,TOX2,PAXBP1,NNAT,GAL3ST4,ZFP2,CASC3,SLC12A2,STAU1,ZC3H4,HEY1,BHLHB9,TP53BP1,GAN" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_100 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 3.53E-04 1.00E+00 1.57E-03 1.43E-02 21 92 "PPP4R4,TMEM108,CALB1,CBLN1,DCLK1,HAPLN1,PLXNA4,DOCK4,DRP2,EMX2,FREM1,GUCY1A1,KCND2,KLHL23,NEFM,SERPINI1,PCDH18,ADGRL3,ZFPM2,ACTR6,DPF3" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 3.53E-04 1.00E+00 1.57E-03 1.43E-02 21 92 "NDRG2,LTBP4,GPRASP2,LHX2,EGFR,EMX2,ADGRV1,FGF11,PCDH17,PPARGC1A,MAP7D2,KCNH2,NCAM2,NELL2,PAX6,PCDH9,PGAM2,NECAB2,SOX11,FAM189A1,SENP7" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_200 kidney_P3_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.55E-04 1.00E+00 1.58E-03 1.43E-02 32 166 "ALCAM,AMPH,VAT1L,ADAM23,CACNA1G,CACNA2D1,CRYM,SNCAIP,VCAN,SPOCK2,GSDME,SNAP91,EYA1,ST3GAL6,FGFR1,SCARA3,IGSF5,TDRKH,FAM107A,HAS2,TM6SF1,NPY,CNTN3,ROBO1,GLDN,SALL1,CNKSR2,TACR1,CUX2,HEY1,LAMP5,SLC38A1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k4 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.58E-04 1.00E+00 1.59E-03 1.45E-02 23 105 "PCDH19,SYT13,CASK,USP2,CHGB,EBF1,TMEM107,GAA,GPT2,ATXN2L,MEIS2,MYH3,FXYD7,NNAT,PCSK5,GPR85,PLTP,ING3,PTPRD,TMEM255A,MEG3,MTERF2,TRIO" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.63E-04 1.00E+00 1.61E-03 1.46E-02 50 298 "CEP126,SPTBN4,ADAM23,ZNF599,SCAPER,PTBP2,CDO1,CRLF1,CLTB,VAX2,IGDCC3,CLIP3,PHF14,DRP2,DNM1L,ELN,CORO2B,HPCAL4,STAU2,C15orf41,ZNF638,SYNPO,SMAP1,ICA1,KNDC1,LRRCC1,HECTD2,MID1,MSR1,TCEAL5,NFIX,PDE4D,GPSM2,TRHDE,DIRAS2,CNTLN,ACSS3,IQSEC3,REV3L,PREX2,CCDC88A,LIMCH1,SPATA7,BDP1,ARHGAP26,SATB2,ASXL3,LRRC8A,STXBP4,TRPS1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE76381_iPSMoleculeCountsPMLog2 3.75E-04 1.00E+00 1.67E-03 1.51E-02 12 39 "SYT13,RUNX1T1,TENM1,STMN2,HS6ST3,MYO5A,TMOD2,PRKACB,RTN1,SNAP25,VGF,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.75E-04 1.00E+00 1.67E-03 1.51E-02 12 39 "SYT13,RUNX1T1,TENM1,STMN2,HS6ST3,MYO5A,TMOD2,PRKACB,RTN1,SNAP25,VGF,CELF4" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_100 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_100 FaceBase_RNAseq 3.85E-04 1.00E+00 1.71E-03 1.55E-02 22 99 "TTLL9,CA4,CBLN1,LHX2,ADGRV1,REEP2,GABRB3,TOX3,MAP7D2,STMN2,SOX21,USP51,SHISAL1,CDH20,NRCAM,IGSF11,PAX6,PRTG,SALL1,SNRPN,ZIC2,DPYSL5" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_200 kidney_P2_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.85E-04 1.00E+00 1.71E-03 1.55E-02 28 139 "ALCAM,AMPH,IL33,CA12,CACNA2D1,CDH2,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,GSDME,SNAP91,ETV1,EYA1,ST3GAL6,FGFR1,IGSF5,TDRKH,FAM107A,HAS2,NEGR1,CNTN3,ROBO2,SALL1,CUX2,TPM2,LAMP5" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_100_k4 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.94E-04 1.00E+00 1.74E-03 1.58E-02 9 24 "CRYM,EYA1,FAM19A2,FAM107A,HAS2,PRTG,SALL1,MAPK12,ANKRD6" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.94E-04 1.00E+00 1.74E-03 1.58E-02 9 24 "CADPS,CACNA2D1,CNTN1,EPB41L2,MRVI1,NEGR1,CLDN11,PTX3,SYNPO2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 3.96E-04 1.00E+00 1.75E-03 1.59E-02 32 167 "CEP126,PDE8B,ATP1A3,LDLRAD4,CACNA2D1,CAMK2A,DRP2,TMTC1,DLL3,STAU2,ZMAT1,TMEM8B,NTNG2,GNG4,LRRCC1,CREG2,GPR155,MSR1,NPR2,PDE4D,GPSM2,SDK2,DIRAS2,CNTLN,IQSEC3,ZNF493,BEND5,MRAP2,SATB2,PIK3R5,SYNPO2,TRPS1" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K2 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.98E-04 1.00E+00 1.76E-03 1.59E-02 46 269 "TTLL9,SLC25A14,PPT2,LRRC3B,GPSM1,HDAC9,MYADM,ARHGAP24,WDR20,FGF11,FGFR1,FOXF2,GFRA2,CSDC2,GSN,GUCY1A1,HMGCL,METTL21A,CDH20,GATD1,KHK,MATN2,OGG1,ZFYVE21,PLEC,PMP22,MAGEL2,PPP3CC,NKAIN4,PRODH,PTPRE,PTPRG,TSPY26P,C12orf49,BAALC,KIAA0895L,STK32B,SBF1,SLC4A3,ELMO2,PDZRN3,ADAMTS17,TMEM121,SH3GLB2,MSRB3,ADAMTS10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.02E-04 1.00E+00 1.77E-03 1.61E-02 18 74 "NDRG2,SPARCL1,BMP7,CDO1,IGDCC3,LYPD1,EDNRB,ADGRV1,PDLIM5,NRBP2,MXI1,NTRK2,PTN,KLHDC8A,ITPRID2,SULF2,TCF12,HEY1" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.02E-04 1.00E+00 1.77E-03 1.61E-02 18 74 "ADGRF5,SPARCL1,SEMA6A,LCORL,BACH1,LDB2,ZNF521,HAPLN1,LPAR4,LIFR,POC1B,GNG2,TMEM255A,PEG10,KLHL4,TEK,FLRT2,ZNF711" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_500 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.04E-04 1.00E+00 1.78E-03 1.61E-02 11 34 "ARHGAP20,APOC1,BOC,AFF2,NSG1,TCEAL6,KCND2,MAP2,PCDH18,MEG3,VSNL1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.08E-04 1.00E+00 1.79E-03 1.63E-02 16 62 "ADGRF5,SPARCL1,SEMA6A,LDB2,ZNF521,HAPLN1,LIFR,TMEM255A,SEMA6D,PEG10,RGL1,ARHGEF9,KLHL4,HEY1,FLRT2,ZNF711" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_200_k4 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.09E-04 1.00E+00 1.79E-03 1.63E-02 17 68 "ARHGAP20,VAT1L,CHGB,CNTN1,EBF1,MRVI1,MEGF10,FREM1,PTPRT,NEGR1,MN1,PTX3,ZFHX4,SLC14A1,CLSTN2,NEK4,NETO1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.09E-04 1.00E+00 1.79E-03 1.63E-02 17 68 "ASIC1,SEPT7,TAOK3,ZMAT1,STMN2,GRIA2,GRIK5,HBA1,TOX2,NFIX,NOVA1,SLC25A23,MEG3,RTN1,BDP1,SIN3B,CELF4" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 4.09E-04 1.00E+00 1.80E-03 1.63E-02 37 203 "KLHL32,PHF12,NUMB,BBS2,ZNF599,PCYT1B,IGDCC3,CSNK1G3,KIAA0586,KLHL5,EIF5,COQ7,SRRM1,OGA,C15orf41,DBF4,ADGRA3,SETD5,GSTCD,CLIP1,SCP2,KIF21A,CHD9,FNDC3A,FAM81A,SEPHS1,SPATA7,MPRIP,STXBP1,SYNE2,TCEA1,SIRT1,TRO,ZKSCAN5,KAT6A,HNRNPA3,ZDHHC20" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K2 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.11E-04 1.00E+00 1.80E-03 1.63E-02 49 292 "EMILIN3,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,ABI3BP,ANKRD44,ELN,LRRC17,FCGRT,TRIM16,STAU2,TVP23A,ZMAT1,ZNF276,GRIK4,SYNPO,CREG2,SRSF12,MSR1,TCEAL5,FXYD7,NFIX,CNTN3,PDE4D,SDK2,EPB41L4B,CNTLN,ACSS3,IQSEC3,BEND5,ZFHX4,MRAP2,LRRK2,DGLUCY,SH3GL3,SLC8A1,PLCB1,ADGRL3,SATB2,PHF24,PIK3R5,TRPS1,TSPAN11,KLHDC1" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_tips_2500 gudmap_RNAseq_e11.5_Ureteric_tips_2500 Gudmap RNAseq 4.14E-04 1.00E+00 1.81E-03 1.64E-02 227 1789 "ABR,AXIN2,ADORA2A,PCDH19,AK2,DOC2A,AMPH,EPB41L5,APOC1,VAT1L,CPNE5,LGR5,CDC14B,SEMA4G,TMEFF1,ARHGDIG,MARCH3,DYNLL1,BACH1,RGS9,NRP2,PROM1,BMP7,BMPR1B,WASF1,MYRF,CA4,CA12,CALB1,ARHGEF2,CRLF1,CHGB,B4GALT6,SLIT2,PPT2,MYL6B,FAM189A2,HOMER3,CNTFR,COL9A1,SLC4A8,IGDCC3,ZNF385A,CRMP1,HAPLN1,HINFP,CRYM,IPCEF1,SIPA1L1,PLXNA4,FAM169A,KIAA0040,CTH,GREB1,CYBB,KATNAL2,TMEM170A,DAPK1,SPOCK2,AIF1L,MFAP3L,SNAP91,SGSM2,CASP8AP2,DPYSL2,ARRDC4,DTNA,DUSP9,FIS1,E2F5,SEZ6L2,EDNRB,SEMA3D,RASA4,EIF1,EMX2,EYA1,CD320,MRVI1,ST3GAL6,SPSB4,FGF12,ZMYND15,SEMA4D,HVCN1,UFM1,RASL10A,SYT17,IGSF5,NFU1,GFER,PPARGC1A,TOX3,KDM2B,POLL,STMN2,SERP2,CACFD1,RNF165,GSTT2,LINGO1,FAM107A,MUM1,HAS2,PADI2,HLF,ACOT7,LRRC75A,SHISAL1,IBA57,SLC35G1,METTL21A,KCNH2,KCNJ16,GATD1,KIT,L1CAM,STMN1,LMO2,LYPLAL1,MATK,AQP11,ADAM11,KITLG,MOV10,SAMD5,MSI1,BLOC1S2,MYCN,NEFM,VWA2,NPY,NRCAM,KSR2,CDK18,PDE1C,PDE4A,PDE1B,PKM,SMOX,PLXNB1,PRIMPOL,SEPT4,FA2H,POLR2F,FSD1,PPP1R1A,PPP5C,CEP41,MAPK4,MASP1,LAMA1,ELOVL2,SPDL1,EML5,PTPRG,NKAIN1,TMEM231,CCDC40,ROGDI,RASGRF2,ZMAT4,RET,RGS4,NUDT11,ROBO2,PCMTD2,GLDN,RPS6KA2,EMID1,RTN1,TRAPPC13,SALL1,MAPK12,SCN2B,SCN8A,HES6,ZNF821,COPZ1,SH3GL3,SHMT2,FHOD3,ST6GAL1,SLC4A3,CXXC4,SNAP25,SOX11,SST,ZC4H2,RGL1,STAC2,STX1A,KANK1,TMEM150C,SYT5,MTCL1,TBCEL,KLHL4,WSCD1,CUX2,ZFPM2,ARL10,BEX4,DCBLD1,TSN,CA14,HSPBP1,RPRM,UBE2H,UCHL1,CCDC136,VLDLR,VSNL1,SPHK2,DPYSL5,ANKS1B,SLC38A1,TMEM178A,CIAPIN1,PPP1R3F,PCBP4,PLD4,FZD3,DOCK8,MARCH8,AP3B2,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_100_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.14E-04 1.00E+00 1.81E-03 1.64E-02 10 29 "USP31,DPP10,CACNA1B,PLCXD3,GRIN3A,GFRA2,NDP,CLDN11,PRPH,CUX2" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_1000 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000 PCBC 4.21E-04 1.00E+00 1.84E-03 1.67E-02 135 992 "ADCY5,ADCY8,ADD2,PTCHD1,SPARCL1,PDZD4,ZFYVE28,PLA2G4C,ARSE,MARCH3,ATP1A3,CARMIL3,AZGP1,LDHD,CA12,CALB1,RUNX1T1,CBS,LDB2,SCARB1,DCLK1,CHRNA4,RAB33A,FAM189A2,FAM19A5,CNTN1,CRYBB1,ABCG1,CRYM,GALNT9,VCAN,RIMS4,SEC14L5,KIF26A,KCTD8,BRINP1,HS3ST2,DOCK2,FAM78B,AASS,RASGRP2,PIPOX,HSPA12B,PPP1R1B,OLFM1,HPCAL4,FLT1,CGREF1,CSPG5,MEGF11,MEGF10,HRASLS5,GABRB3,MTHFD2,GCK,ALDH1L1,GNAO1,GNG4,GSTT2,LINGO1,IRAK3,HNF4G,NEGR1,LRRC75A,ITGAM,KCND2,KCNN1,KCNN2,KHK,KIF5A,CAMK2N2,PIK3AP1,MATK,MMP17,MT1M,MX1,MYCN,FXYD7,ALDH1L2,NPTX1,NPTX2,P2RY1,PDE4B,SLC10A4,CYTL1,TMEM38A,PLCB2,JAKMIP1,FXYD1,PLTP,EPB41L4B,PPP2R2B,PPP2R2C,PRODH,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,RORB,MRAP2,SGSM1,FERMT1,SHMT2,SLA,PREX2,SLC6A11,SEPHS1,OGDHL,SNRPN,HECW1,UNC5B,SSTR1,SEPT3,NECAB1,RHBDL3,SYN1,ARC,SYN2,TACR1,KLHL4,ARHGAP9,TEK,CHST8,ENHO,TIMP4,RELL2,PIK3R5,RASD2,IL34,UGT8,VAV1,VIPR2,SLC30A3,NETO1" Coexpression Atlas PCBC_ratio_BronchSmoothMuscl_vs_SC_cfr-2X-p05 Bronchial Smooth Muscle Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.32E-04 1.00E+00 1.89E-03 1.71E-02 242 1923 "ADCY6,ADD1,C1QTNF1,ALCAM,SRPX,MARCH4,LTBP4,AMPD2,AMPD3,SEMA7A,C6orf89,SMIM29,ARHGDIA,ADAM15,BBS2,JAZF1,AP1M1,SGCE,CA12,CACNA2D1,CAST,LDB2,SLC16A4,CDC25B,EVI5L,CCPG1,NUMBL,CFL2,COPB2,CHN1,ARHGAP22,SLIT2,TPP1,STOML1,CLTB,HOMER3,SUMF2,MAGED1,ZNF521,CNRIP1,C2CD2,RNF14,CLIP3,CSF1,OSBPL3,SOCS5,PDE4DIP,CST3,GPSM1,MYADM,ARHGAP24,RASSF2,TBC1D5,SCRN1,GIT2,RUSC2,GSDME,RHOBTB1,DMPK,CD99L2,RCAN1,TOM1,SNX29,TSPAN5,HIPK3,TMTC1,EGFR,MBNL2,RASA4,IRAK4,CERCAM,MRNIP,C3orf18,TMEM35A,VPS13B,LRRC17,MTSS1L,SLC43A2,SPEG,RRAGB,SIRPB1,CLVS1,ABCA8,FAM198B,TAOK3,FCGRT,GTF2IRD2,AMOTL2,PRKAG2,FHL1,SCARA3,FOXF2,PCYOX1,FOXO3,FLNC,FLYWCH1,TMEM175,GALNT15,TRAF3IP2,FAM120B,ERAP1,TMEM8B,GDF9,CSDC2,DHRS4,GP1BB,BTN2A1,GSN,HAS2,TOX2,ZHX1,MAN1B1,SYNPO,HMGCL,IFI16,IL6ST,TMEM240,INPP1,KIFC3,STXBP5,LAMA2,LAMP2,LSS,MAN2A2,MAP4,MBNL1,MEIS1,MEIS2,KITLG,MITF,MN1,DBNL,MT1M,NRBP2,SAMD14,LAYN,MYO5A,NBL1,NFE2L2,ALDH1L2,NPR2,NPTX1,NUCB2,CLDN11,OXTR,PCDHGC3,ENPP2,GNG2,ZDHHC8,XRN1,PKM,PLEC,PCDH18,PMP22,PPP3CC,MAPK3,MASP1,BCAS3,BDNF-AS,RIPOR1,TMEM231,PID1,RAP1GDS1,OXR1,REV3L,RGS4,RNH1,KIRREL1,RPS6KA2,ST6GALNAC6,CLIP1,MAPK12,SCN8A,PRCD,SCP2,TNFRSF19,GALNT10,MRAS,RASA3,SGK1,FHOD3,CCDC92,SEC31A,ABLIM3,NBPF1,WDR47,FAM214B,SIRT2,SLC12A4,SLC14A1,ABTB1,SMARCD3,SNAP25,ZHX3,ZSWIM8,GLT8D1,TEX2,TSPYL2,CAMTA2,ITPRID2,ERBIN,ST5,RGL1,TACC1,PDLIM2,TCF12,PCDHGC5,SZT2,PCDHGA11,PCDHGA10,TNS2,CYB561A3,ZMAT3,THRA,NACC2,TK2,TNS1,TPM2,RGMB,TRIO,DCBLD1,TTC3,FAM155A,FLRT2,PLPPR2,TOM1L2,WIPF1,NPDC1,ATP6V0E2,ZBTB38,PRTFDC1,PRDM8,RNF103,SEMA3B,FIP1L1,PCBP4,PLSCR4,RTN4,UBE3B,MSRB3,SNX14,FRMD6" Coexpression Atlas facebase_RNAseq_e9.5_OlfPlac_2500 facebase_RNAseq_e9.5_OlfPlac_2500 Gudmap RNAseq 4.45E-04 1.00E+00 1.94E-03 1.76E-02 209 1633 "ACHE,TMCC3,AXIN2,PLEKHH1,KIAA1211,KLHL13,PCDH19,C1QTNF1,ZNF687,DOC2A,TRMT9B,FGD2,PI16,MYH7B,EPB41L5,NT5C3B,TMEFF1,ARRB2,BCHE,NRP2,BLM,ZNF599,PROM1,BMP7,WASF1,CA4,CA12,HAP1,PTBP2,HIP1R,MTMR7,CBFA2T2,ARHGEF2,CDH2,LRWD1,TBRG4,CACNA2D2,CBARP,NRXN3,MYL6B,FAM19A5,HOMER3,CNTFR,PCYT1B,COL9A1,BAG4,IGDCC3,ZNF385A,HAPLN1,ABCG1,CRYM,OSBPL3,CNTNAP2,PLXNA4,FAM169A,GREB1,KATNAL2,AIF1L,USP3,CDON,CPEB2,DTNA,DUSP9,FARSB,E2F5,TSPAN5,YAF2,EIF4G1,RGS17,EMX2,EPB41,EPHB1,ERBB4,ETV1,ADGRV1,EYA1,REEP2,CEP78,POLR1B,SPSB4,FGF12,FHL1,PCYOX1,SYT3,NELFCD,POMT1,TMEM107,CINP,PDLIM5,KHDRBS3,FUT9,B4GALNT1,MTHFD2,SYT17,TCERG1,DBF4,GLI2,TOX3,GLUL,STARD3,KIAA1958,LNX1,GPD2,ZNF496,RNF165,PSIP1,FAM107A,FAM222A,HAS2,TOX2,FRMD5,HSF2,LRRC75A,SHISAL1,METTL21A,KCNH2,KIT,MAP2,AQP11,MBP,ADAM11,MEIS1,MEST,KCTD6,AFDN,MSI1,TAGLN3,MXI1,MYCN,NNAT,VWA2,NRCAM,KSR2,CDK18,PDPK1,SNX10,RETREG1,PKM,GPSM2,SLC25A23,PLXNB1,PSAT1,PPP2R2B,PPP5C,MAPK4,PRODH,GDPD1,LAMA1,ELOVL2,ZIK1,PTPN13,EML5,NKAIN1,CCDC40,SUSD4,ZMAT4,DPF2,FIGN,RFX3,NUDT11,GSTCD,RPS6KA2,HUNK,RTN1,TRAPPC13,SALL1,MAPK12,SATB1,KIF21A,FERMT1,SHMT2,ST6GAL1,CCDC92,PKNOX2,CXXC4,IFT122,INAVA,SOX11,SPTB,KANK1,TMEM150C,ANKRD28,MMS19,WSCD1,DOCK9,SIRT1,ITGB3BP,HEY1,BEX4,CA14,HIRA,UBC,USP1,KLC2,ZFP41,DPYSL5,TFIP11,MEIS3,DHX33,SLC38A1,TUBA1A,ADAMTS9,PCBP4,WNK2,FZD3,TTC7A,AP3B2,CPNE4,SPATA13" Coexpression Atlas gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_500 kidney single cell_e11.5_MetanephMesench_StemCellamp_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.49E-04 1.00E+00 1.96E-03 1.78E-02 55 339 "MTUS1,CDC14B,TMEFF1,ARHGDIG,ARHGEF25,HOMER3,CNTFR,IQCK,COL9A1,COL9A3,ZNF521,CSNK1E,VCAN,ARMCX4,MYEF2,DUSP9,EBF1,FGF13,FOXO3,SMC2,BRSK1,KCNMB4,SERP2,PSIP1,ZDHHC15,KIAA1755,STMN1,MEIS1,MEIS2,MEST,SAMD14,MYCN,LINC00672,NNAT,NTRK2,NLE1,FSD1,PTN,C1orf54,TSPY26P,FIGN,MEG3,SH3GL3,DZIP1,CXXC4,SOX11,SIN3B,CUX2,C18orf54,ENHO,FAM155A,MEIS3,SLC38A1,PCBP4,NETO2" Coexpression Atlas ratio_EB_vs_SC_2500_K4 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 4.50E-04 1.00E+00 1.96E-03 1.78E-02 47 278 "AGT,SPARCL1,PHYHD1,ARHGDIG,CHRD,MYOM1,CAMK2A,CAPN3,AKAP6,MROH8,RASGEF1C,DMD,CD99L2,ECM2,ABCA8,GTF2IRD2,FLNC,CHL1,CYP46A1,CSDC2,GGT5,TPPP,FAM107A,ATOH8,UBE2QL1,ALDH1L1-AS2,IGF1,PACRG,MAPT,MITF,PDE1C,PLCL1,PMP22,PTH1R,CRTAC1,RNASE1,CCDC92,SLC8A1,FAIM2,GPRIN3,HEY1,TNS1,SYNPO2,PDIA2,TMEM161B-AS1,TOM1L2,DPF3" Coexpression Atlas Lungmap Mouse Lung PND1 Epithelial Subtype AT1-E Lungmap Mouse Lung PND1 Epithelial Subtype AT1-E Lungmap CCHMC 4.55E-04 1.00E+00 1.98E-03 1.80E-02 40 226 "SYN3,ACTN1,AP2A2,OSBPL6,ALCAM,MYRF,DDR1,LRRFIP1,SRSF11,ARHGAP22,FAM189A2,QKI,AKAP5,SPOCK2,DPYSL2,EGFR,FAM198B,TRIM16,TPPP3,CPLX2,GCNT2,LYVE1,GSN,LIMS1,MAP6,NBL1,ZFYVE21,PKM,PMP22,PPP3CA,PTPRE,RASGRF2,MEG3,SGK1,LIMS2,LIMCH1,MPRIP,TNS1,TP53BP2,LAS1L" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_200 kidney_P1_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.57E-04 1.00E+00 1.98E-03 1.80E-02 25 120 "ALCAM,AMPH,IL33,CACNA2D1,CACNB4,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,ETV1,EYA1,FGFR1,IGSF5,TDRKH,HAS2,NEGR1,MEIS2,CNTN3,ROBO2,SALL1,CUX2,PCDHB9,TPM2" Coexpression Atlas PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05 Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.65E-04 1.00E+00 2.02E-03 1.83E-02 144 1071 "ABHD6,NDRG2,AGT,C1QTNF3,AMPD2,BIN1,C6orf89,APLP1,VAT1L,SEMA4G,ASGR1,ATP6V0A1,BCHE,PROM1,AP1M1,RAB29,SLC16A4,SCARB1,ARHGAP33,SLIT2,CLCN3,AKAP7,IGDCC3,NECTIN3,ZNF385A,CPS1,HAPLN1,CRYM,CST3,TCAF1,RHOBTB1,FAM107B,DMD,RCAN1,TOM1,DUSP9,EDIL3,EDN1,ANKRD46,HIPK3,KLHL5,FAM13A,EGFR,MBNL2,ELN,HSD17B14,CLVS1,FAM198B,SH3YL1,PTK2B,ST3GAL6,FCGRT,FDFT1,SLC9B2,ZBED3,SDCBP2,IQGAP2,TMEM8B,NEU3,SESN1,GHR,GPD1,GSN,ZHX1,HMGCL,HMGCR,C2orf72,IL6R,IL6ST,ITPKA,SLC35G1,KCNJ16,TMEM110-MUSTN1,LAMP2,SFXN5,LSS,MATN2,MIA2,SCAMP5,MITF,NRBP2,MYO9A,NPR2,PCSK5,PDE3A,ENPP2,PFKFB4,PGAM2,SERPINI1,PIK3R1,SMOX,PCDH18,PLTP,SCHIP1,PPARA,PPP1R1A,SMIM10L2B,MASP1,KLK6,PTCH1,BEND5,PRRT2,RGS3,ROBO2,RXRA,DGLUCY,SGK1,MYO18A,HKDC1,SIRT2,LIMCH1,SNCA,PDZRN3,ZSWIM8,TEX2,UNC5B,ITPRID2,APOM,RGL1,ADHFE1,VPS13A,COBL,PDLIM2,SZT2,VWCE,AKTIP,AMACR,TST,FLRT2,PLPPR2,TOM1L2,VSNL1,ELFN1,ATP6V0E2,CRB2,REEP1,ZNF189,RNF103,TMEM178A,SEMA3B,ST7,MARCH8,NHSL1,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k1 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.72E-04 1.00E+00 2.05E-03 1.86E-02 26 127 "PCDH19,ADGRB3,BMPR1B,CCK,COL9A1,CRYM,SIPA1L1,GSDME,GRIN3A,EDN3,TVP23A,HAS2,KCND1,MEIS1,COMMD5,PCDH8,ING3,SALL1,MAPK12,HES6,DHX30,RADIL,SLC9A5,ENHO,TPM2,NETO2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 4.76E-04 1.00E+00 2.06E-03 1.87E-02 23 107 "KIAA1324,ARRB2,ATP1A3,ATP6V1G2,CACNA1A,THSD7A,NECTIN3,DGKB,DLL3,TMEM8B,PPARGC1A,GRIK4,GUCY1B1,KCNN3,KIT,MTRF1L,TRHDE,MASP1,GDPD2,SPATA7,RBFOX3,TRIM9,PRRT4" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_100 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.79E-04 1.00E+00 2.07E-03 1.88E-02 18 75 "CALB1,PLXNA4,DOCK4,DRP2,PLXNC1,EMX2,NRN1,FREM1,GUCY1A1,KCND2,KLHL23,MATN2,KITLG,NEFM,PCDH18,ADGRL3,ACTR6,LYPD6" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.80E-04 1.00E+00 2.08E-03 1.88E-02 21 94 "FMNL2,PPP4R4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,EMX2,MTSS1L,KLHL23,KITLG,SERPINI1,HUNK,RASA3,SLC4A3,UHRF1BP1L,ADGRL3,ACTR6,DPF3" Coexpression Atlas GSM605872_100 "Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 4.91E-04 1.00E+00 2.12E-03 1.93E-02 17 69 "ABCD2,LY86,GDA,CSF1R,VCAN,CYBB,IGSF6,TLR7,SIRPB1,FCGR1A,HP,IFI16,ITGAM,MSR1,PILRA,PID1,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.92E-04 1.00E+00 2.13E-03 1.93E-02 32 169 "PCDH10,SYT13,VAT1L,INSYN2B,DST,RUNX1T1,DCLK1,CDO1,CRLF1,ERC2,SPOCK3,DLX1,EGFR,EYA1,TMEM132C,FOXF2,MEGF10,LPAR4,GRIA2,IFI16,MYH3,PCDH8,TRHDE,ZFHX4,ROBO1,CSRNP3,ANKRD6,SOX11,TROVE2,ADGRL3,SYNPO2,PCDH20" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_500 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.95E-04 1.00E+00 2.14E-03 1.94E-02 29 148 "FMNL2,LGR5,PPP4R4,MAGI1,PLXNA4,DOCK4,DAPK1,RASGRP1,KLHL5,EMX2,NRN1,GALC,IGF1,KLHL23,KITLG,MYO9A,PPP3CC,GDPD1,SEMA6D,TNFRSF19,STUM,RASA3,SLC4A3,KDM3A,ST5,ACTR6,ELFN1,LYPD6,FRMD6" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_200 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.96E-04 1.00E+00 2.14E-03 1.94E-02 31 162 "DOC2A,BMP7,CALB1,CRLF1,HAPLN1,IPCEF1,CNTNAP2,CTH,DUSP9,TENM1,EMX2,SPSB4,FGF12,RASL10A,GALC,MAP7D2,PADI2,FRMD5,KCNJ16,L1CAM,AQP11,VWA2,LAMA1,EML5,RASGRF2,RET,SCN8A,FHOD3,NUDT10,RPRM,VSNL1" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_100 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.12E-04 1.00E+00 2.20E-03 2.00E-02 20 88 "AMH,LGR5,PPP4R4,CADPS,CACNA2D2,SCRN1,DTNA,MRO,PLXNC1,ERBB4,PTK2B,FGF13,GATM,PPARGC1A,GPR37,KLHL23,RASGEF1B,MRAS,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k3 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.12E-04 1.00E+00 2.20E-03 2.00E-02 20 88 "EMILIN3,ADRB2,MYOM1,CNTN1,COL9A1,PLCXD3,NCALD,MEGF10,GFRA2,LIMS1,HECTD2,MEIS1,NPTX2,CNTN3,PCDH9,NALCN,LGI2,SH3BGR,TPM2,MSRB3" Coexpression Atlas GSM854285_500 "Myeloid Cells, DC.8-4-11b+.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2" "Immgen.org, GSE15907" 5.13E-04 1.00E+00 2.21E-03 2.00E-02 65 419 "FMNL2,ADCY6,TMCC3,ADORA2A,ALCAM,SEMA7A,CASK,ZBTB10,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,LY86,SLC4A8,GDA,ABCG1,CSF1R,CST3,PNPLA8,CYBB,RASSF2,MAMLD1,DNM1L,PLXNC1,RASA4,ENO2,IGSF6,SIRPB1,ZMYND15,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,HSF2,INSM1,JAK2,KTN1,TTYH2,MYO5A,NPR2,PFKFB3,CCSER2,PLCL1,PLTP,PID1,ROGDI,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,ST5,SULF2,TMEM150C,ARC,SLC44A1,SYNPO2,TRPS1,SPIRE1,PLD4" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_500 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500 PCBC 5.22E-04 1.00E+00 2.24E-03 2.03E-02 75 499 "ABHD6,LGR5,LINC00173,CA4,CAMK2A,P2RX6,NOG,LHX2,CNTFR,NRG2,SEC31B,HAPLN1,PLCXD3,BOC,ARHGAP24,DGKG,LYPD1,EDN1,EGR3,EMX2,NCALD,NRN1,CLVS1,PRAM1,DLC1,ATP13A4,TPPP3,IP6K3,GPR162,ADAM28,FAM107A,GUCY1B1,UBE2QL1,ZNF491,INSM1,ITPKB,SYTL4,CLEC18A,MAP2,MAP6,MEIS1,MEIS2,SAMD5,TAGLN3,RTL5,NPY,CNTN3,PAX6,PRTG,PDE1C,ENPP2,SDK2,VSTM2L,RELN,ZFHX4,KLHDC8A,EMID1,MELTF-AS1,PEAR1,ARX,CCDC92,DMRTC1,CLSTN2,SSPO,ZEB1,NR2E1,RIMBP2,ZIC1,EMX2OS,CRB2,MKRN3,DPYSL5,ADAMTS9,DOCK8,FAM182B" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000_k5 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.29E-04 1.00E+00 2.27E-03 2.06E-02 47 280 "ACADM,OSBPL6,ASPA,SLC4A4,CFLAR,CA4,CA12,ISPD,SLC16A4,CLTC,OSBPL3,GUCD1,PAN3,PIPOX,FGFR3,ATP13A4,FOLR2,FUT9,GALC,GHR,NCOA7,MYO6,MYO9A,IGSF11,ENPP2,RETREG1,DRAM2,POU6F1,RANBP3L,PTH1R,ELOVL2,SH3TC2,LRRK2,RYR3,KIF21A,SPATA7,SPP1,RBM26,PBLD,NEK4,FAM208A,SATB2,VWCE,LRRC8A,TRPS1,VLDLR,ADAMTS9" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 5.34E-04 1.00E+00 2.29E-03 2.08E-02 11 35 "APLP1,THSD7A,EBF1,SEZ6L2,NRN1,STMN2,IGFBPL1,MAP6,TAGLN3,NEFM,RTN1" Coexpression Atlas Facebase_ST1_e9.5_OticVesic_500 e9.5_OticVesic_top-relative-expression-ranked_500 FaceBase_ST1 5.35E-04 1.00E+00 2.29E-03 2.08E-02 62 396 "MTUS1,AMT,PKP4,ATP1A1,BMP7,RAB29,CA4,CLDN10,USP2,CDH2,CDO1,SOCS6,VAX2,PICK1,COL9A1,COL9A3,GAL3ST1,CSNK1E,SCRN1,PCOLCE2,HSD17B14,EYA1,C15orf41,ZNF276,KCNMB4,CACFD1,RNF165,IGFBPL1,NKD1,AQP11,KCTD6,MITF,AFF1,LYRM9,NPY,SLC11A2,PAX6,ENPP2,PLCD1,SLC25A23,SCHIP1,PPP2R2B,FIGN,SETD5,EMID1,PTGR2,ARFGAP1,CMTR2,SPP1,SPART,ADAMTS17,MTCL1,WSCD1,KIAA0930,MTMR14,TRIO,RPRM,XRCC4,ZFAND5,URM1,PDSS2,NETO2" Coexpression Atlas gudmap_kidney_e10.5_UretericTrunk_HoxB7_500 kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.35E-04 1.00E+00 2.29E-03 2.08E-02 62 396 "PCDH19,ADGRF5,CEP126,BCL7A,ZNF599,PROM1,CA4,CA8,CALB1,CD38,RCBTB2,B4GALT6,SLIT2,HAPLN1,FAM169A,HDAC4,DUSP9,SEMA3D,PLEKHA1,EMX2,SH3YL1,ACSL4,RACK1,SPSB4,FLT1,C2orf88,SYT17,C15orf41,IGSF5,GGTA1P,PPARGC1A,RAB30,TOX3,FAM19A2,KCNJ16,L1CAM,CHIC1,KITLG,TCEAL5,PRTG,SEPT4,PTH1R,PTPRB,EML5,TMEM255A,RET,NUDT11,KIF21A,SOX11,ZC4H2,NUDT10,KLHL4,CUX2,TEK,BEX4,DCBLD1,CA14,UCHL1,VLDLR,VSNL1,ZNF711,SLC38A1" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.42E-04 1.00E+00 2.32E-03 2.10E-02 19 82 "ARHGAP20,LTBP4,ADAM23,CACNA2D1,CBLN1,SLIT2,VCAN,EDNRA,EGFR,LRRC17,GFRA2,FREM1,GUCY1A1,GUCY1B1,LAMA2,PLTP,PTCH1,ROBO2,STOX2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.42E-04 1.00E+00 2.32E-03 2.10E-02 19 82 "ARHGAP20,CALB1,CBLN1,HAPLN1,VCAN,DOCK4,DRP2,EDNRA,PLXNC1,FREM1,GUCY1A1,KLHL23,MATN2,MEIS1,NEFM,PCDH18,TMEM255A,ADGRL3,ZFPM2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_500 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.45E-04 1.00E+00 2.33E-03 2.11E-02 13 46 "AKAP5,PLXNA4,NRN1,AFF2,IGF1,KCND2,MAP2,MATN2,NEXMIF,PCDH18,MEG3,ADGRL3,ZFPM2" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500_k1 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.46E-04 1.00E+00 2.33E-03 2.11E-02 27 135 "LCORL,LGR5,PDE8B,INSYN2B,SYNJ1,ARHGEF7,CNR1,DZIP3,GREB1,DOCK4,DYNC1I1,RASGRP1,SCML2,MAP7D2,KCND2,KITLG,NEXMIF,GLIPR1L2,SERPINI1,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,LARP4,DMXL2,ZNF23" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K3 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 5.52E-04 1.00E+00 2.35E-03 2.13E-02 51 311 "NDRG2,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,CACNA1B,CBARP,MYL6B,LETMD1,MYADM,SPOCK2,SEMA3D,EGFR,RGS17,RPS6KC1,MED12L,FGF11,FGF12,STAMBP,TPPP3,TVP23A,PCDH17,PARD3B,FAM107A,FRMD3,LRRC75A,MBP,MEIS1,MOV10,SAMD14,HS6ST3,GPR173,SMOX,FXYD1,NECAB2,RNH1,ATXN7,HES6,FERMT1,DOK5,UNC5B,ADAMTS17,MCF2L,PCDHGA2,SLC44A1,ENHO,TST,TOM1L2,NDRG4,SH3GLB2" Coexpression Atlas gudmap_RNAseq_e15.5_Podocytes_2500_K3 gudmap_RNAseq_e15.5_Podocytes_2500_K3 Gudmap RNAseq 5.68E-04 1.00E+00 2.42E-03 2.19E-02 18 76 "APLP1,CADPS,MYRF,CACNA2D2,CRMP1,FAM78B,MAMLD1,ERBB4,ERCC2,CORO2B,AFF2,RNF165,SHISAL1,KCNH2,MEST,RETREG1,ANKFN1,SYP" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.73E-04 1.00E+00 2.44E-03 2.21E-02 47 281 "METAP1D,AXIN2,AMPH,OGT,LRCH2,LGR5,CDK10,SEMA4G,PDE8B,INSYN2B,CTH,GREB1,SACS,DOCK2,RASGRP1,NRN1,FGF11,KHDRBS3,NEU3,SESN1,IL6ST,FAM69A,SLC35G1,GPR155,NPR2,ENPP2,MAPK9,GDPD1,CNNM2,GDPD2,PTGR2,PRCD,TNFRSF19,STUM,ABLIM3,KDM3A,ARHGAP26,LHPP,ADAMTS17,RPGRIP1L,TCF12,DCBLD1,LYPD6,REEP1,TMEM178A,SNX14,FRMD6" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200_k2 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.81E-04 1.00E+00 2.47E-03 2.24E-02 14 52 "ADORA1,PCDH19,DOC2A,KIAA0040,GREB1,EPHB1,ST3GAL6,FKTN,ADGRA3,CLEC18A,NPY,OXTR,EMID1,HEY1" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_100_k4 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.81E-04 1.00E+00 2.47E-03 2.24E-02 14 52 "THSD7A,TMCC2,IQGAP2,IGSF5,PARD3B,MAPT,RETREG1,MBOAT7,PTPRO,DUSP15,DDN,STX1A,TMEM150C,TMEM178A" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000 DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.87E-04 1.00E+00 2.49E-03 2.26E-02 113 814 "EMILIN3,TMCC3,ADD1,ADORA1,AP2A2,AGT,TBC1D14,SORCS2,AK2,TAOK1,C1QTNF3,ARHGAP20,LTBP4,AMH,SEMA7A,ARHGDIG,ARRB2,BACH1,RGS11,ST3GAL5,DDR1,CALM1,CAMK2G,VXN,CBLN1,ARHGEF1,SCARB1,RBM39,RNF14,SNCAIP,ARHGEF4,PUM1,ARHGAP32,DAPK3,SPOCK2,DBI,DBN1,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,RASL12,NRN1,TUBB3,FGFR1,FYN,GATM,CSDC2,MAP7D2,LPAR4,GPR37,GRB10,SPACA9,GUCY1A1,IL6ST,KIF2A,LAMA2,SMAD1,MAPT,MEF2C,MOV10,NRBP2,MYO7A,NEXMIF,NFIX,NNAT,SEMA5B,PLEC,FXYD1,PCDH18,EXOSC10,PRKACB,PTPRE,MEG3,SEC14L1,ARX,SMARCA4,SNRPN,SPP1,RBM26,SULF2,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,USP22,OBSL1,PUM2,TNS1,NR2C2,TST,SGK3,UBTF,UCHL1,USP1,ZIC1,ZFAND5,INTS3,STOX2,ADAMTS9,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_500 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 5.89E-04 1.00E+00 2.50E-03 2.26E-02 74 493 "PHYHD1,APOC2,USP37,SPTBN4,ADAM23,ZNF599,BMPR1B,LDLRAD4,CACNA2D1,LRBA,KCNAB3,SRSF11,FAM149A,COL9A1,IGDCC3,CRYBB1,CRYM,DZIP3,PHF14,SPOCK2,JAKMIP2,GSDME,DDX46,DLX1,SHANK1,CASP8AP2,DUSP9,TMEM35A,EPB41,NSRP1,TMEM132C,AFF2,SMC2,TMEM8B,ZNF638,MAP7D2,ADAP1,RABL2A,USP51,KNDC1,LRRCC1,KCNJ5,KIT,TM6SF1,MAGEL2,POU6F1,DIRAS2,STRC,RBBP8,ZMAT4,DUSP15,DGLUCY,FHOD3,ST6GAL1,CNKSR2,NLGN1,PREX2,PEX26,DHX30,CCDC88A,LIMCH1,BDP1,SOX11,UHRF1BP1L,SATB2,ITGB3BP,ASXL3,SYNPO2,TRPS1,CA14,USP1,ZNF184,DNAH10,MRPL47" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_k1_200 kidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.91E-04 1.00E+00 2.51E-03 2.27E-02 25 122 "C1QTNF1,EPB41L5,UPRT,THSD7A,DOCK4,ARHGAP24,AIF1L,OPTN,TLR7,ACSL4,ST3GAL6,ST6GALNAC3,GALC,IQGAP2,MALT1,PARD3B,SYNPO,MYO6,PTH1R,PTPRO,RIPOR1,ROBO2,FAM81A,TMEM150C,FRYL" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.98E-04 1.00E+00 2.53E-03 2.29E-02 20 89 "USP31,APC,FOXN3,VCAN,DNM1,GFRA2,GRIA2,RASSF8,BACH2,MEIS2,KANSL1,PTPRG,PTPRO,ROBO2,ZHX3,CLASP2,ADGRL3,PCDHB7,ERCC6L2,TRPS1" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_k3_1000 kidney_e13.5_Podocyte_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.01E-04 1.00E+00 2.54E-03 2.31E-02 37 207 "ZNF521,CRYM,SNCAIP,VCAN,CENPL,GSDME,EYA1,IGSF5,FREM1,HAS2,NEGR1,NEFM,NPY,NOVA1,PDCD2,OLA1,SPDL1,PTN,RBBP6,TSPY26P,RMI1,SALL1,CNKSR2,SLC4A3,CMTR2,NUDT10,ADAMTS17,TAF9,CUX2,PCDHB9,PCDHB3,ITGB3BP,BHLHB9,STXBP4,TRPS1,STOX2,NETO2" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_200 dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.09E-04 1.00E+00 2.57E-03 2.33E-02 32 171 "FMNL2,PPP4R4,CALB1,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,EMX2,NRN1,AFF2,KLHL23,MATN2,KITLG,AFF1,MYO9A,SERPINI1,PCDH18,TNFRSF19,RASA3,SLC4A3,SNCA,KDM3A,UHRF1BP1L,ADGRL3,DNAH7,ZFPM2,ACTR6,PCDH20,WNK3,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.20E-04 1.00E+00 2.62E-03 2.37E-02 30 157 "USP31,DPP10,ANK2,CACNA1B,CNR1,HAPLN1,BRINP1,GRIN3A,EDIL3,SEMA3D,ETV1,CORO2B,FGF13,SYT17,PPARGC1A,FRMD5,SAMD5,MAGEL2,C12orf49,CCDC112,SATB1,CXXC4,CMTR2,CLASP2,TROVE2,NEK4,ITGB3BP,SGK3,RPRM,SOCS4" Coexpression Atlas GSM399391_500 "alpha beta T cells, T.DP.Th, 4+ 8+ TCR-/lo 69-, Thymus, avg-3" "Immgen.org, GSE15907" 6.27E-04 1.00E+00 2.65E-03 2.40E-02 58 367 "FMNL2,ADCY6,RNF157,SYT13,PITPNM2,SEMA7A,ARNTL,ALDH7A1,BACH1,LDLRAD4,PRC1,RCBTB2,CNN3,WHRN,AKAP12,LRIG1,CSNK1E,PPP1R16B,DGKG,DAPK1,NYAP1,ABCC5,RASGRP1,TNK2,USPL1,SLC43A2,IP6K2,GPR162,DCLK2,NIM1K,KCNH2,STMN1,LIG4,AQP11,AFF1,XRRA1,PDE4D,ZDHHC8,PLCL1,SLC25A23,POU6F1,RIPOR1,CEP97,ZDHHC14,SATB1,DZIP1,ST8SIA1,ANKRD6,TET1,SMARCA4,MPRIP,ANKRD28,SLC37A2,TCF12,PRRT1,TRIO,SSBP2,NHSL1" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 6.58E-04 1.00E+00 2.77E-03 2.51E-02 49 298 "EMILIN3,KIAA1324,SRPX,ARHGAP20,CDK10,ADGRB2,NRP2,ZNF599,CACNA1G,LDLRAD4,CA12,CACNA2D1,KCNAB3,CDO1,CRLF1,ABI3BP,ANKRD44,CSF1R,RASA4,ELN,LRRC17,FCGRT,TRIM16,FYB1,TMEM8B,ZNF276,GSN,SYNPO,CREG2,SRSF12,TCEAL5,NFIX,CNTN3,PLCL1,PRKAR1B,GDPD2,ACSS3,ZCWPW1,ZMAT4,ZFHX4,DGLUCY,SH3GL3,ASAP3,SLC8A1,ADGRL3,PHF24,FAM189A1,TSPAN11,CADM2" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.83E-04 1.00E+00 2.88E-03 2.61E-02 13 47 "EMILIN3,ADRB2,MYOM1,COL9A1,PLCXD3,NCALD,MEGF10,GFRA2,LIMS1,NPTX2,NALCN,SH3BGR,MSRB3" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K4 gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K4 Gudmap RNAseq 6.84E-04 1.00E+00 2.88E-03 2.61E-02 26 130 "DOC2A,CALB1,CRLF1,SLIT2,DUSP9,EMX2,ERBB4,FGF12,RASL10A,L1CAM,KITLG,NEFM,VWA2,MAPK4,RASGRF2,RET,NUDT11,GLDN,NKAIN2,TMEM150C,SYT5,RPRM,VSNL1,ANKS1B,TMEM178A,AP3B2" Coexpression Atlas PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-plasmid_cfr-2X-p05 Ectoderm Differentiated Cells-method_NA_vs_Ectoderm Differentiated Cells-method_plasmid-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.85E-04 1.00E+00 2.88E-03 2.61E-02 22 103 "AXIN2,ADORA1,PCDH10,RASL11B,NRP2,NOG,NGEF,NRG2,LYPD1,CDON,EDNRA,TMEM132C,ZIC5,ITPKB,CLEC18A,SAMD5,PDE1B,IRX1,ZFHX4-AS1,LRRN3,ZFHX4,DOCK8" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_500 kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.85E-04 1.00E+00 2.88E-03 2.61E-02 60 384 "KCNH8,KLHL32,PCDH19,SEMA6A,LGR5,BARD1,BCL7A,PROM1,BMPR1B,CALB1,CD38,B4GALT6,SLIT2,HAPLN1,FAM169A,DUSP9,EDNRB,SEMA3D,PLEKHA1,EMX2,SH3YL1,ACSL4,NOP56,IGSF5,MAP7D2,HAS2,ZDHHC15,KIT,LMO2,GPR155,KITLG,SAMD5,THYN1,TCEAL5,PRTG,SEPT4,SPDL1,ZIK1,EML5,TMEM255A,RET,MORC4,FIGN,NUDT11,ROBO2,FHOD3,PREX2,SOX11,NUDT10,TMEM150C,TAF9,KLHL4,CUX2,TEK,BEX4,CA14,UCHL1,VSNL1,SLC38A1,SOCS4" Coexpression Atlas JC_iEC_1000 JC_iEC_top-relative-expression-ranked_1000 PCBC 6.90E-04 1.00E+00 2.90E-03 2.63E-02 133 987 "EMILIN3,GALNT13,KIAA1211,ADRA1D,HECW2,KLHL13,CASKIN1,PCDH19,KIAA1324,OSBPL6,MARCH4,PCDH10,BBOX1,AMH,SEMA7A,PI16,INSYN2B,TMEM108,AZGP1,ST3GAL5,MYRF,CALB1,THSD7A,HAP1,CH25H,DGKI,LONRF2,DLGAP1,NOG,AKAP5,CRYBB1,RIPOR2,AIF1L,MFAP3L,GRIN3A,CPEB2,DPP6,MAMLD1,EBF1,TMTC1,TENM1,CALCRL,PIPOX,HSPA12B,FGF12,ATP13A4,HHIPL1,IGSF5,GGT5,GNAO1,GNG4,LNX1,MCHR1,STMN2,ZBTB49,BVES,LINGO1,TOX2,ARHGAP36,MIER3,KCNF1,PIK3AP1,MATK,CHST6,SAMD5,MSR1,NCF2,NDP,NPTX1,NRCAM,NTRK2,OXTR,PCDH9,PCSK1,PCSK5,PDE4D,SLC10A4,PMP22,TRHDE,FA2H,SNRK,PTPRB,PTPRE,RIPOR1,SH3TC2,RNASE1,EMID1,SALL1,SCN8A,STUM,SGK1,ST6GAL1,PREX2,LIMS2,CXXC4,OGDHL,FAM126B,SPP1,ITPRID2,THSD1,RHBDL3,ARC,SYT1,KLHL4,PCDHGB6,PCDHGB2,PCDHA6,SLC35G2,VWCE,TEK,ARL10,ASXL3,IL34,SYNPO2,TRPS1,NUTM2A,DCBLD1,UGT8,MGAT5B,VGF,VLDLR,VSNL1,KCNK12,TRIM9,LYPD6,CELF4,EML6,LAMP5,SLC30A3,TMEM178A,ZNF37BP,NETO2,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k4 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.92E-04 1.00E+00 2.90E-03 2.63E-02 30 158 "ADORA1,AMPH,EPB41L5,USP37,LGR5,DYNLL1,RBM39,KIAA0040,GREB1,HSD17B14,ST3GAL6,FGFR3,FOXO3,KHDRBS3,MTHFD2,IGSF5,AP4S1,CLEC18A,TM6SF1,NPY,OXTR,PALM,PTPN13,EMID1,SMARCA4,CAMTA1,TRIM2,HEY1,ZNF24,SPIRE1" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.98E-04 1.00E+00 2.92E-03 2.65E-02 11 36 "EPB41L5,ST3GAL6,IGSF5,FREM1,CLEC18A,TM6SF1,OXTR,SALL1,ANKRD6,NEK4,HEY1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 6.99E-04 1.00E+00 2.92E-03 2.65E-02 17 71 "KIAA1324,ATP1A3,NECTIN3,EMX2,FHL1,FUT9,GRIK4,INSM1,KCNN3,KIT,PAX6,MASP1,GDPD2,LMO3,RBFOX3,TRIM9,PRRT4" Coexpression Atlas gudmap_developingGonad_P2_testes_500 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.99E-04 1.00E+00 2.92E-03 2.65E-02 63 408 "TMCC3,ADD1,ADORA1,C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,DDR1,CALM1,VXN,CBLN1,SCARB1,RBM39,RNF14,ARHGEF4,PUM1,ARHGAP32,SPOCK2,DBI,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,RASL12,REEP2,TUBB3,SCML2,FGFR1,FYN,GATM,GPR37,GRB10,IL6ST,TTYH2,MEF2C,NRBP2,MYO7A,NEXMIF,NFIX,NNAT,SEMA5B,PTPRE,MEG3,ARX,PUM2,TST,SGK3,UCHL1,USP1,ZFAND5,VPS35L,PCBP4,RTN4" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k1 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.17E-04 1.00E+00 2.99E-03 2.71E-02 23 110 "ADORA1,EPB41L5,SNCAIP,EYA1,ST3GAL6,IGSF5,FREM1,IFI16,LIG4,TM6SF1,OXTR,PRTG,FAM184A,GAL3ST4,SALL1,ANKRD6,CMTR2,CLSTN2,NEK4,ANKRD28,PCDHB9,HEY1,RGMB" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.17E-04 1.00E+00 2.99E-03 2.71E-02 34 187 "BIN1,SFMBT2,ARRB2,MS4A7,LY86,CSF1,CSF1R,CYBB,DOCK4,EGR3,IGSF6,FCGR1A,FCGRT,FOLR2,FYB1,GATM,ADAM28,HPGDS,LILRB4,GPR34,GSN,NCKAP1L,VSIG4,IFI16,IL6R,IL6ST,MEF2C,P2RY13,TREM2,GAL3ST4,SGK1,SAMSN1,P2RY12,DOCK8" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 7.17E-04 1.00E+00 2.99E-03 2.71E-02 34 187 "BIN1,SFMBT2,ARRB2,MS4A7,LY86,CSF1,CSF1R,CYBB,DOCK4,EGR3,IGSF6,FCGR1A,FCGRT,FOLR2,FYB1,GATM,ADAM28,HPGDS,LILRB4,GPR34,GSN,NCKAP1L,VSIG4,IFI16,IL6R,IL6ST,MEF2C,P2RY13,TREM2,GAL3ST4,SGK1,SAMSN1,P2RY12,DOCK8" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.35E-04 1.00E+00 3.06E-03 2.78E-02 8 21 "NSG1,TPPP3,TAGLN3,NNAT,SLC10A4,PRPH,SST,UCHL1" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200_k1 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.35E-04 1.00E+00 3.06E-03 2.78E-02 8 21 "BMP7,CALB1,CRLF1,DUSP9,EMX2,SPSB4,RASL10A,LAMA1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.42E-04 1.00E+00 3.09E-03 2.80E-02 24 117 "ZSCAN18,TMEM108,SLC4A4,MYRF,CALB1,CNTFR,AKAP5,ZNF521,CLIP3,DNM1,TSPAN5,FLNC,TCEAL6,NKD1,KCND2,MATN2,MEIS1,NEFM,NME4,PCDH18,PTN,KCNIP1,ZFPM2,TRPS1" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_1000_k1 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.56E-04 1.00E+00 3.14E-03 2.85E-02 10 31 "BACH1,DBN1,GSDME,MAPT,NNAT,PCDH8,ROBO2,SNRPN,RBM26,PCBP4" Coexpression Atlas PCBC_ratio_MESO-30_vs_SC_cfr-2X-p05 Mesoderm Day 30_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 7.67E-04 1.00E+00 3.19E-03 2.89E-02 210 1659 "ADCY6,AGT,C1QTNF3,SPARCL1,SRPX,PCDH10,LTBP4,BIN1,SEMA7A,C6orf89,APAF1,GAS7,APLP1,SEMA4G,IGDCC4,ARRB1,ARSE,ASGR1,CFLAR,BMP7,DST,ST3GAL5,AP1M1,C5,MYRF,CFAP410,CAST,HIP1R,SLC16A4,CDH2,CCPG1,CFL2,SLIT2,TPP1,CLTB,CNTFR,COL4A5,MAGED1,ENTPD4,HAPLN1,RNF14,VCAN,CST3,GPSM1,TCAF1,ZFYVE16,HEPH,RUSC2,LYPD1,RHOBTB1,FAM107B,CD99L2,SLC29A4,RCAN1,ARRDC4,DUSP9,EDIL3,EDN1,HIPK3,SEMA3D,KLHL5,EGFR,MBNL2,ING4,CERCAM,ELN,HSD17B14,LRRC17,RRAGB,FAM198B,SH3YL1,PTK2B,CHST15,FCGRT,FGFR3,AMOTL2,SUCO,FLNC,TMEM175,PDLIM5,SARAF,GALC,ERAP1,FREM1,GP1BB,CCDC184,CACFD1,BTN2A1,GSN,GUCY1A1,HAS2,ZHX1,MAN1B1,SYNPO,HMGCL,IFI16,C2orf72,IL6ST,KIFC3,LAMP2,LIFR,NCOA7,MAN2A2,MAP2,MATN2,MATN3,MEIS2,MEST,MGAT3,MIA2,KITLG,MN1,DBNL,NRBP2,MXI1,LAYN,NBL1,NUCB2,PALM,PCSK5,PFKFB3,SERPINI1,PIK3R1,PLEC,SMOX,PLTP,PMP22,SCHIP1,SDK2,PPP3CC,NKAIN4,KLK6,WBP1L,LAMA1,ELOVL2,RIPOR1,PID1,OXR1,RGS3,RNASE1,RNH1,KIRREL1,MELTF-AS1,CLIP1,TNFRSF19,GALNT10,MRAS,SGK1,HKDC1,FNDC3A,CCDC92,SEC31A,ANKRD6,NBPF1,WDR47,FAM214B,SIRT2,SLC12A4,CPEB4,SMARCD3,LIMCH1,LMBRD1,PDZRN3,KDM3A,ZSWIM8,SPP1,TEX2,PEG10,CLSTN2,CAMTA2,ITPRID2,APOM,SEPT8,RGL1,SULF2,TACC1,PDLIM2,PCDHGB6,GPR161,ZMAT3,THRA,NACC2,TNS1,TPM1,TPM2,AMACR,DCBLD1,TTC3,FLRT2,PLPPR2,TOM1L2,LMF1,WIPF1,NPDC1,XRCC4,ELFN1,CRB2,DPYSL5,SPIRE1,RNF103,ADAMTS9,TMEM178A,SEMA3B,PCBP4,RNF170,MSRB3,ADAMTS10,SNX14,FRMD6,SENP7" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.77E-04 1.00E+00 3.22E-03 2.92E-02 29 152 "KLHL13,CALB1,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,NRN1,FLNC,FREM1,GUCY1A1,NKD1,KCND2,KLHL23,MATN2,MEIS1,KITLG,MYO9A,NEFM,PCDH18,TMEM255A,SLC4A3,KDM3A,ADGRL3,ZFPM2,ACTR6,LYPD6,WNK3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.78E-04 1.00E+00 3.22E-03 2.92E-02 9 26 "SPARCL1,EDNRA,LRRC17,FREM1,GUCY1A1,PCDH9,TMEM255A,ROBO2,VSNL1" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_200_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.78E-04 1.00E+00 3.22E-03 2.92E-02 9 26 "BACH1,RBM39,LPAR4,CHIC1,TMLHE,FNIP1,SYNE2,SSBP2,ADAMTS9" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 Gudmap RNAseq 7.86E-04 1.00E+00 3.25E-03 2.95E-02 22 104 "ADD2,NRXN3,IQCK,IGDCC3,ERBB4,ADGRV1,AFF2,TUBA8,RNF165,KCNJ5,KCNJ16,MAP2,MAP6,NEFM,NOVA2,ELOVL2,RTN1,HSPA4L,PREX2,SNAP25,WNT7A,AP3B2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K1 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 7.86E-04 1.00E+00 3.25E-03 2.95E-02 22 104 "PTCHD1,FGD2,APOC1,ABCG1,CRYM,CDON,EGFR,SLC43A2,EYA1,CLVS1,FGF12,TPPP3,GCNT2,PCDH17,KCNMB4,FAM107A,FRMD3,SAMD5,HES6,HEY1,NDRG4,FRMD6" Coexpression Atlas PCBC_EB_blastocyst_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 7.86E-04 1.00E+00 3.25E-03 2.95E-02 74 498 "AGT,APOC2,CACNA1G,MYRF,LHX2,FAM19A5,IGLON5,COL9A1,IGDCC3,PHACTR3,CNTNAP2,DNAH9,DPP6,DUSP9,EDN3,EMX2,ADGRV1,NRN1,TMEM132C,FOXF2,CHL1,CPLX2,GFRA2,FREM1,CCDC184,STMN2,GRIA2,C1QL4,GRM8,GUCY1A1,UBE2QL1,IGFBPL1,HP,SHISA6,CELF5,C2orf72,IGF1,NKD1,INSM1,CLEC18A,MAPT,NEFM,NELL2,NNAT,NTRK2,PAX6,PCDH8,PDZRN4,NECAB2,MAGEL2,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,HUNK,KCNIP1,TMEM200C,SNAP25,CABCOCO1,SOX3,CLSTN2,SST,ASXL3,RIMBP2,ZIC1,KCNT2,CRB2,MKRN3,DPYSL5,FAM181A" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000_k2 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.89E-04 1.00E+00 3.26E-03 2.95E-02 18 78 "C6orf89,EPB41L5,CDC14B,SNAP91,IGSF5,BRD8,DHX35,PAXBP1,CLEC18A,MAP4,SETD4,PDE1C,PRIMPOL,ANKRD16,LAMA1,PTPN13,SALL1,SUPT20H" Coexpression Atlas GSM854320_500 "Myeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2" "Immgen.org, GSE15907" 7.91E-04 1.00E+00 3.26E-03 2.96E-02 62 402 "MTUS1,ABCD2,AMPD3,PI16,SUGT1P4-STRA6LP-CCDC180,GAS7,APOC2,CASK,ATP1A3,ADAM15,SCARB1,LY86,GDA,CSF1R,CSF2RA,GALNT9,VCAN,CST3,CYBB,MYADM,DGKG,IGSF6,TLR7,SIRPB1,F5,FCGR1A,FCGR3A,OLFM1,FLT1,CAMKK2,TPPP3,GCNT2,ADAP1,SLC2A6,IRAK3,PADI2,HP,IFI16,LRRC25,IL6R,ITGAM,LAMP2,LIFR,MSR1,P2RY13,NCF2,P2RY1,PFKFB4,PLTP,PILRA,MARCH1,PID1,SH3BP2,SLC11A1,SULF2,PLCB1,KIAA0930,TIAM1,TLR4,TRIO,PLD4,NLRP3" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k1_200 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.93E-04 1.00E+00 3.26E-03 2.96E-02 12 42 "CD38,LY86,CSF1R,F8,FYB1,LYVE1,NCKAP1L,MSR1,PTPRB,SGK1,ARHGAP9,TEK" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k5 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.93E-04 1.00E+00 3.26E-03 2.96E-02 12 42 "RUNX1T1,AP4M1,CHL1,HAS2,ZNF827,PCDH8,PLTP,PTPRD,RNASEL,MEG3,CLSTN2,TPM2" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_200_k4 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.93E-04 1.00E+00 3.26E-03 2.96E-02 12 42 "DOC2A,BMP7,GREB1,DUSP9,ST3GAL6,IGSF5,CLEC18A,OXTR,LAMA1,EMID1,SALL1,WSCD1" Coexpression Atlas GSM854312_500 "Myeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 7.94E-04 1.00E+00 3.27E-03 2.96E-02 63 410 "ADRB2,ZNF608,MTUS1,TBC1D14,ALCAM,ABCD2,AMPD3,PI16,SUGT1P4-STRA6LP-CCDC180,CASK,NUMB,ATP1A3,ATP6V0A1,BACH1,GPR146,ST3GAL5,GDA,CSF1,CSF1R,CSF2RA,MYADM,FBXL5,GSDME,CPEB2,ARRDC4,DENND4A,IGSF6,SIRPB1,ST3GAL6,FCGR3A,GCNT2,GGT5,GSN,SLC2A6,IRAK3,HNMT,HP,IFI16,LRRC25,IL6R,ITGAM,LAMP2,SFXN5,ASPRV1,P2RY13,NCF2,NFE2L2,PDE1B,PFKFB4,SMOX,MBOAT7,PILRA,SEC14L1,SLC11A1,ABTB1,TMCC1,DMXL2,KIAA0930,TPCN2,SLC44A1,TLR4,TRPM2,NLRP3" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000_k4 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.05E-04 1.00E+00 3.31E-03 3.00E-02 48 293 "EMILIN3,TMCC3,ADORA1,SORCS2,C1QTNF3,ARHGAP20,LTBP4,AMH,SEMA7A,ARHGDIG,RGS11,ST3GAL5,VXN,CBLN1,ARHGEF4,SPOCK2,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,LRRC17,RASL12,FYN,GATM,CSDC2,GPR37,IL6ST,LAMA2,MEF2C,NRBP2,MYO7A,NFIX,SEMA5B,PLEC,FXYD1,PTPRE,MEG3,SPP1,TBL1X,SIN3B,NR2C2,TST,SGK3,UBTF" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 8.05E-04 1.00E+00 3.31E-03 3.00E-02 48 293 "SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ATP1A3,BARD1,NRP2,IL33,CAMK2A,CAMK2B,KCNAB3,CREM,CRYBB1,SNX29,RASGRP2,NCALD,CDKL3,SEMA4D,DLL3,ABLIM2,FYB1,LYVE1,NTNG2,ADAP1,SCIN,GPR155,MITF,MYH3,ETFRF1,ENPP2,PRKAR1B,MASP1,GDPD2,STRC,ZMAT4,DUSP15,KCNIP3,CCDC92,INAVA,SAMSN1,LAMP5,CADM2,DNAH10,PRRT4" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.28E-04 1.00E+00 3.40E-03 3.08E-02 59 379 "NDRG2,ADCY5,PI16,MYOM1,ADAM23,NRP2,GPR146,DST,CACNA2D1,CAST,ENTPD2,GDA,OSBPL3,CNTNAP2,MFAP3L,CHRDL1,DMPK,CPEB2,DTNA,HIPK3,PCOLCE2,MRVI1,NRN1,FGF1,FHL1,FUT9,CHL1,GALNT15,IGSF5,GCNT2,ADAM28,TPPP,GSN,HLF,IFI16,SLC35G1,KCNF1,MBP,PRKCB,RGS4,SCN7A,STUM,SH3BGR,FHOD3,SLC14A1,SYN2,TLR4,TNS1,TPM2,RGMB,SYNPO2,PPIL6,RBFOX3,AGMO,PLSCR4,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_100 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 8.29E-04 1.00E+00 3.40E-03 3.08E-02 17 72 "LGR5,CALB1,PLXNA4,PLXNC1,LRRC17,NRN1,AFF2,GATM,FREM1,GUCY1A1,KCND2,KLHL23,MATN2,KITLG,PCDH18,ADGRL3,ACTR6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 8.36E-04 1.00E+00 3.42E-03 3.10E-02 86 597 "AS3MT,ADGRF5,FAM135A,CDC14B,CCAR2,DYNLL1,SEC11C,NAE1,PRMT9,CA12,NFS1,COPB2,EPS15L1,CNN3,PCYT1B,TBPL1,CNRIP1,CSNK1G3,DZIP3,PNPLA8,DBI,KIAA0753,ZC3H11A,FAM107B,SEC16A,CDON,E2F6,EBF1,COQ7,RABEPK,STX2,SPEG,RACK1,KAT8,SEC24B,VTI1B,DCTN2,ST6GALNAC3,MSANTD4,NFU1,COPS8,ADGRA3,STON1,PRDM5,MUM1,RASSF8,MBD1,BLOC1S2,PTOV1,MYO7A,NACA,NFYA,PDCD2,PDE4B,EXOSC10,WBP1L,PSMA6,QRICH1,PTPRB,RIPOR1,PPP2R3C,ROBO1,KIRREL1,ELP2,HUNK,PUF60,BTBD3,LIMCH1,MYCBP2,MMS19,TAF9,SIN3B,TIAM1,ACTR6,TP53BP2,ELP5,AMACR,DCBLD1,CA14,ZKSCAN5,FLRT2,XPO1,ZSCAN26,ZFAND5,ZDHHC20,FRMD6" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_250 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_250 FaceBase_ST1 8.46E-04 1.00E+00 3.46E-03 3.14E-02 35 196 "C3orf14,TAOK1,RAB33A,NECTIN3,KATNAL2,ZFYVE16,SCRN1,KATNAL1,EFCAB2,CSPG5,STAU2,C15orf41,RAB30,TDRKH,CACFD1,IGFBPL1,PACRG,PAX6,MINDY2,PPP2R5E,GDPD1,SLC25A36,PBRM1,ARMH4,CCDC112,HSPA4L,KIF21A,NUDT10,ADAMTS17,CCDC173,NR2E1,NPL,TRPS1,XRCC4,ZIC1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_100 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 8.67E-04 1.00E+00 3.54E-03 3.21E-02 19 85 "PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,DRP2,PLXNC1,EMX2,FREM1,KCND2,KLHL23,MAP2,PCDH18,TMEM255A,ADGRL3,ACTR6,VSNL1,LYPD6" Coexpression Atlas ratio_ECTO_vs_SC_2500_K4 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 8.71E-04 1.00E+00 3.56E-03 3.22E-02 34 189 "LINC00173,NOG,SEC31B,SHANK1,WDPCP,GMPR2,PRAM1,TAOK3,EVL,FAM49B,DISC1,SULT1C4,ADAM28,LYVE1,HPGDS,ADAM22,PCBP3,PDE4D,SNX10,FAM216A,SCHIP1,PILRA,SH3KBP1,RELN,PTPRE,BAALC,MELTF-AS1,KCNIP1,ZNF354C,LRRC24,ZFP41,DOCK8,MSRB3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.71E-04 1.00E+00 3.56E-03 3.22E-02 28 146 "ARHGAP20,LTBP4,ADAM23,CACNA2D1,CBLN1,SCARB1,SLIT2,VCAN,EDNRA,EGFR,PLXNC1,LRRC17,NRN1,IQGAP2,GFRA2,FREM1,GUCY1A1,GUCY1B1,LAMA2,MATN2,PCDH18,PLTP,PTCH1,TMEM255A,ROBO2,ADGRL3,VSNL1,STOX2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k2 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.73E-04 1.00E+00 3.56E-03 3.22E-02 27 139 "EMILIN3,TAOK1,C1QTNF3,SPARCL1,ARHGAP20,LTBP4,PTCH2,PUM1,EDNRA,MBNL2,ELN,LRRC17,CSDC2,IGF1,LAMA2,MEF2C,NRBP2,NFIX,FXYD1,MEG3,ARX,RCOR3,TBL1X,OBSL1,TNS1,NR2C2,UBTF" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_200 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.76E-04 1.00E+00 3.57E-03 3.23E-02 14 54 "LGR5,CALB1,DOCK4,DAPK1,DRP2,EMX2,NRN1,KLHL23,MATN2,KITLG,SLC4A3,UHRF1BP1L,ADGRL3,ACTR6" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_100_k3 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.77E-04 1.00E+00 3.57E-03 3.24E-02 15 60 "C1QTNF3,DPP10,IL33,SEMA3D,TMTC1,RASSF8,IFI16,KCND2,NOVA1,RELN,CSRNP3,SCN7A,ST8SIA1,PCDHB9,PCDH20" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K0 facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K0 Gudmap RNAseq 8.94E-04 1.00E+00 3.63E-03 3.29E-02 33 182 "C1QTNF1,MYOM1,NRP2,UBE2L6,NRXN3,ARHGEF6,DGKB,RCAN2,TLR7,RASL12,CHST15,FCGRT,TPPP3,GDF9,LOXL3,GUCY1A1,SHC3,MX1,P2RX7,PDE3A,FXYD1,PTN,ZMAT4,RGS4,EMID1,NKAIN2,PDLIM2,TNS2,GPRIN3,GALNT17,ENHO,TNS1,IL34" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_200 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.94E-04 1.00E+00 3.63E-03 3.29E-02 33 182 "HECW2,ADGRF5,NRP2,LDB2,CD38,HAPLN1,ELMO1,EBF1,EDN1,EDNRB,CALCRL,FLT1,PDLIM5,FYB1,PCDH17,LYVE1,HPGDS,LPAR4,ICA1,IGF1,LMO2,TM6SF1,MEF2C,SNRK,PTPRB,TMEM255A,SGK1,PREX2,LIMCH1,THSD1,KLHL4,TEK,ZNF711" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.99E-04 1.00E+00 3.65E-03 3.31E-02 22 105 "NCKAP5,SEMA6A,APAF1,APOC1,ATP1A3,LDB2,SCARB1,RASGRP2,DLC1,TMEM164,LPAR4,ELOVL5,HMGCR,ZDHHC15,LSS,MEF2C,LAYN,NPY,TMEM255A,ARHGEF9,PCDHB10,VSNL1" Coexpression Atlas PCBC_ratio_Lung Fibroblast_vs_SC_cfr-2X-p05 Lung Fibroblast_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.16E-04 1.00E+00 3.71E-03 3.37E-02 240 1931 "ACTN1,ADD1,ALCAM,SRPX,MARCH4,LTBP4,SEMA7A,C6orf89,SMIM29,ARHGDIA,RGS20,ADAM15,BBS2,BCHE,DST,SYNJ2,AP1M1,SGCE,RAB29,CA12,CAST,PRC1,ARHGEF25,SLC16A4,ENTPD6,ARHGEF2,CDC25B,CCPG1,NUMBL,CFL2,CHN1,ARHGAP22,SLIT2,CLCN3,TPP1,STOML1,CLTB,NGEF,HOMER3,ANKRD35,SUMF2,MAGED1,CNRIP1,CLOCK,RNF14,CLIP3,CSF1,OSBPL3,SOCS5,PDE4DIP,CST3,GPSM1,DOCK4,MYADM,TBC1D5,SCRN1,GIT2,RUSC2,DMPK,CD99L2,DPH1,RCAN1,TSPAN5,TMTC1,EGFR,MBNL2,IRAK4,CERCAM,MRNIP,ELN,C3orf18,TMEM35A,EPB41L2,LRRC17,MTSS1L,SIRPB1,KATNAL1,MRVI1,CLVS1,ACSL4,TAOK3,FCGRT,FKTN,AMOTL2,FHL1,SCARA3,FOXF2,FOXO3,FLNC,FLYWCH1,TMEM175,KHDRBS3,FAM120B,GHDC,ERAP1,SEPT9,CSDC2,DHRS4,GPR37,SERP2,BTN2A1,GSN,HAS2,TOX2,ZHX1,MAN1B1,HMGCL,HNMT,C9orf129,IFI16,IL6ST,INPP1,ITGA7,ITPKB,KIFC3,STXBP5,LAMA2,LAMP2,LIFR,LSS,MAN2A2,MAP4,MATN2,MBNL1,MEIS1,MEIS2,KITLG,MITF,DBNL,MT1M,NRBP2,LAYN,MYO5A,NBL1,NFE2L2,ALDH1L2,NPR2,NPTX1,NUCB2,CLDN11,OXTR,PCDHGC3,ENPP2,ZDHHC8,CCSER2,PKD1,XRN1,PKM,GPSM2,PLCD1,PLEC,PCDH18,PMP22,PPP3CA,PPP3CC,MAPK3,SAMD9,BDNF-AS,RIPOR1,PID1,RAP1GDS1,REV3L,RGS3,RGS4,RNH1,KIRREL1,RPS6KA2,ST6GALNAC6,CLIP1,MAPK12,SCP2,TNFRSF19,PEAR1,GALNT10,MRAS,RASA3,SGK1,MYO18A,CCDC92,SEC31A,ABLIM3,NBPF1,WDR47,FAM214B,SLC8A1,SIRT2,SLC12A4,SMARCD3,DOK5,ZHX3,ZSWIM8,TEX2,CAMTA2,ITPRID2,SSTR1,ERBIN,MPRIP,SEPT8,RGL1,TACC1,PDLIM2,NR2F1-AS1,TCF12,PCDHGC5,PCDHGB7,SZT2,PCDHGA11,TNS2,CYB561A3,THRA,NACC2,TK2,TNS1,TPM2,RGMB,TRIO,DCBLD1,TTC3,UBC,PLPPR2,TOM1L2,WIPF1,NPDC1,ATP6V0E2,ZBTB38,SPIRE1,PRTFDC1,PRDM8,RNF103,TUBA1A,SEMA3B,NAV3,FIP1L1,PCBP4,PLSCR4,RTN4,PHTF2,MSRB3,SNX14,FRMD6" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 9.24E-04 1.00E+00 3.74E-03 3.39E-02 7 17 "CACNA2D1,VCAN,PDLIM5,REV3L,ERCC6L2,RGMB,SSBP2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 9.32E-04 1.00E+00 3.77E-03 3.42E-02 20 92 "PCDH10,INSYN2B,DST,DCLK1,SPOCK3,EYA1,TMEM132C,SCML2,FOXF2,MEGF10,LPAR4,IFI16,MYH3,PCDH8,TRHDE,ZFHX4,CSRNP3,ADGRL3,SYNPO2,SOCS4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.32E-04 1.00E+00 3.77E-03 3.42E-02 20 92 "SYN3,CACNA1B,NRXN3,DGKB,MED12,EBF1,DENND4A,FGF14,NOP56,GABBR1,RAB30,PTPRT,LSAMP,NTRK3,PDE3A,SCN7A,SLC8A1,THSD1,ASTN2,ST7" Coexpression Atlas adipose tissue adipose tissue Human Protein Atlas 9.51E-04 1.00E+00 3.84E-03 3.49E-02 30 161 "C1QTNF1,SRPX,ABCD2,GYG2,CALB2,CNTFR,PLXNA4,SLC29A4,EBF1,PCOLCE2,TMEM132C,GALNT15,GHR,LYVE1,GPD1,ATOH8,HAS2,ITGA7,C2CD4C,KCNB1,MT1M,PLIN1,PPP1R1A,PTX3,S100B,MESP1,ARC,SLC19A3,TIMP4,PRRT4" Coexpression Atlas GSM538263_500 "Myeloid Cells, DC.8-4-11b+.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2" "Immgen.org, GSE15907" 9.58E-04 1.00E+00 3.87E-03 3.51E-02 63 413 "FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,MYOM1,ADAM23,CFLAR,LARGE1,UBE2L6,B4GALT6,ARHGAP22,LY86,SLC4A8,CSF1R,OSBPL3,CST3,CYBB,MYADM,RASSF2,ARRDC4,EBI3,PLXNC1,RASA4,ENO2,IGSF6,SIRPB1,ZMYND15,RAB30,LOXL3,ADAP1,SLC2A6,HSF2,JAK2,KIT,ASPRV1,PFKFB3,CCSER2,ROGDI,RGS12,LRRK2,RTN1,SEMA6D,ST8SIA1,SLC8A1,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,SULF2,TMEM150C,ARC,SLC44A1,TRPS1,ZBTB38,SPIRE1,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingGonad_e11.5_testes_500 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.59E-04 1.00E+00 3.87E-03 3.51E-02 66 437 "ADD1,EPB41L5,APLP1,BACH1,DDR1,CALM1,CAMK2G,COL9A1,RBM39,CRMP1,RNF14,CLIP3,CSNK1E,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,GSDME,DNM1L,EDNRA,MBNL2,EPB41L2,TUBB3,FGFR1,MEX3B,DLL3,KIAA1958,LPAR4,STMN2,GRB10,BACH2,NKD1,INSM1,MAPT,TAGLN3,NEFM,NNAT,GNG2,OLA1,PIK3R1,EXOSC10,PRKACB,ZIK1,ZFHX4,MEG3,ARX,SMARCA4,SNRPN,RBM26,SPART,TROVE2,FBXW11,KLHL4,TRIM2,PUM2,TST,USP1,ZIC1,ZFAND5,INTS3,STOX2,PCBP4,RTN4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K4 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 9.60E-04 1.00E+00 3.87E-03 3.51E-02 39 227 "TTLL9,BCHE,NRP2,CA4,CA12,CBLN1,CLCN3,AKAP12,CHRDL1,PLEKHA1,RASGRP2,PIPOX,CD320,AMOTL2,SEMA4D,NOP56,KIAA1958,LPAR4,SLC35G1,CDH20,AQP11,IGSF11,PRTG,PLTP,MAGEL2,FSD1,GDPD2,PTPN13,CEP97,SALL1,SNRPN,PBLD,MTCL1,BEX4,RGMB,TST,CFAP298,ZIC2,LAMP5" Coexpression Atlas PCBC_DE_fibroblast_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_1000 PCBC 9.69E-04 1.00E+00 3.91E-03 3.54E-02 132 987 "KCNH8,ACHE,ADCY8,GALNT13,ADD2,SEMA6A,PCDH10,UNC79,PDZD4,APOC1,LGR5,ARSE,KIF1A,ADGRB1,BMP7,BTK,CASTOR3,C5,MYRF,CACNA1B,CALB1,CBLN1,CBS,CLDN10,USP2,LHX2,FAM189A2,IGLON5,COL9A1,COL9A3,GAL3ST1,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,BRINP1,SPOCK3,FAM78B,SEMA3D,ERBB4,PIPOX,RASL12,ADGRV1,FGF13,TVP23A,MEGF10,HRASLS5,GABRA3,GABRB3,GAD1,GATM,GFRA2,FREM1,GNAL,LPAR4,GPR37,TMEM121B,GRM2,FAM222A,HAS2,IGFBPL1,HP,SHISA6,CELF5,NKD1,CDH20,KCND2,KCNF1,KCNN1,KIT,MATK,MATN3,MYT1,TCEAL5,BEX5,PRTG,SLC10A4,SEMA5B,JAKMIP1,PDZRN4,PPP1R1A,PPP2R2B,PPP2R2C,RASGEF1B,MAPK7,MAPK10,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,RET,PRIMA1,MRAP2,HUNK,SALL1,TMEM200C,SH3BGR,SH3GL3,CABCOCO1,SNRPN,SOX3,SOX15,MCF2L2,SSTR2,NUDT10,TMEM150C,KLHL4,FAM189A1,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,TRPM2,CA14,TUBB2A,RPRM,VIPR2,RBFOX3,KCNK12,ZIC1,ZIC2,ZNF708,KCNT2,ANKS1B,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.85E-04 1.00E+00 3.97E-03 3.59E-02 21 99 "FMNL2,KLHL13,CALB1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,KLHL23,MATN2,KITLG,MYO9A,ZFHX4,SLC4A3,KDM3A,UHRF1BP1L,ST5,ADGRL3,ZFPM2,ACTR6" Coexpression Atlas PCBC_MESO-5_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 9.91E-04 1.00E+00 3.98E-03 3.61E-02 73 494 "KCNH8,ADORA1,UNC79,PDZD4,DPP10,APOC1,LGR5,ARSE,KIF1A,BMP7,BTK,C5,MYRF,CCK,USP2,PLEKHB1,IGLON5,COL9A1,COL9A3,GAL3ST1,NRG2,CNTNAP2,PLCXD3,SV2B,FAM78B,ERBB4,RASL12,ADGRV1,MEGF10,HRASLS5,GABRB3,GATM,GNAL,TMEM121B,FAM222A,HAS2,IGFBPL1,SHISA6,KCNF1,KIT,MATN3,IGSF11,PCDH8,SEMA5B,JAKMIP1,RELN,LAMA1,ELOVL2,STK32A,SLC25A48,FAM184A,KHDRBS2,PRIMA1,MRAP2,SALL1,TMEM200C,MCF2L2,SSTR2,TMEM150C,FAM189A1,GALNT17,PIK3R5,TRPM2,CA14,RPRM,RBFOX3,KCNK12,KCNT2,ANKS1B,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas PCBC_DE_blastocyst_500 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_500 PCBC 9.91E-04 1.00E+00 3.98E-03 3.61E-02 73 494 "KCNH8,SEMA6A,PCDH10,UNC79,PDZD4,LGR5,RASL11B,KIF1A,CALB1,CLDN10,FAM189A2,FAM19A5,IGLON5,COL9A1,GAL3ST1,IPCEF1,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,BRINP1,DPP6,PIPOX,ADGRV1,PPP1R1B,MEGF10,HRASLS5,CHL1,GABRB3,GAD1,GATM,FREM1,GNAL,GSTT2,HAS2,IGFBPL1,SHISA6,KCND2,KIT,NNAT,SEMA5B,JAKMIP1,PDZRN4,PPP2R2B,PPP2R2C,RASGEF1B,RELN,LAMA1,ELOVL2,SLC25A48,FAM184A,RET,PRIMA1,HUNK,TMEM200C,MCF2L2,KLHL4,FAM189A1,GALNT17,ENHO,CSMD1,PIK3R5,TRPM2,RPRM,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,GAL3ST3,AP3B2,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.98E-04 1.00E+00 4.00E-03 3.63E-02 12 43 "CA4,CA12,CALB1,ISPD,EMX2,IGSF5,CLEC18A,MYO6,RETREG1,RYR3,SCN8A,SATB2" Coexpression Atlas ratio_SC_vs_MESO_1000_K4 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 9.99E-04 1.00E+00 4.00E-03 3.63E-02 10 32 "GALNT9,TMEM35A,TUBB3,AKAP3,NPTX1,NTRK3,PCSK1,RASGRF2,SPP1,LAMP5" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_100_k3 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 9.99E-04 1.00E+00 4.00E-03 3.63E-02 10 32 "BACH1,RUNX1T1,LPAR4,CHIC1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_k4_1000 kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.00E-03 1.00E+00 4.00E-03 3.63E-02 38 220 "RALGAPA1,USP31,SPARCL1,AMPD3,NRP2,MTMR2,IL33,CA8,CH25H,CBLN1,CHN2,TAOK2,ABCG1,PLXNA4,ELMO1,SEMA3D,TMTC1,GALNT15,LPAR4,IRAK3,IGF1,STXBP5,SMAD1,TM6SF1,PFKFB3,PMP22,RASGEF1B,MAPK12,FNIP1,EPN2,LIMCH1,ZHX3,ANKRD28,KLHL4,TCF4,DOCK9,UCHL1,AGMO" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500_K3 facebase_RNAseq_e10.5_NeuroEpith_central_2500_K3 Gudmap RNAseq 1.02E-03 1.00E+00 4.10E-03 3.71E-02 16 67 "ADD2,NRXN3,ABCG1,AATK,KIF26A,SEZ6L2,EMX2,EPHB1,CCDC184,MAPT,SHC3,KITLG,NTRK2,SERPINI1,LIMS2,TACC1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_200 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.03E-03 1.00E+00 4.14E-03 3.75E-02 31 169 "FAM135A,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,AKAP5,EDIL3,EPHB1,ETV1,FOXF2,MEGF10,CHL1,LYVE1,RAB40B,IFI16,PCDH8,RGS4,ZFHX4,PEG10,COBL,ZFPM2,ERCC6L2,RGMB,SYNPO2,TRPS1,FAM13C,ACTR3B,MSRB3,NETO1,SOCS4" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_k2_1000 kidney_adult_RenMedVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.05E-03 1.00E+00 4.18E-03 3.79E-02 50 312 "MTUS1,HECW2,ADGRF5,SEMA6A,SEMA7A,ARNTL,ATP1B3,ADAM15,GPR146,CFLAR,LDB2,CD38,CLTB,TMEM184B,PPP1R16B,PITPNC1,EDN1,EDNRB,KLHL5,CALCRL,EZH1,F8,DLC1,FLT1,PDLIM5,TRIM16,INPP5K,PCDH17,GGTA1P,ICA1,SCIN,ITPKB,LIFR,LMO2,MEIS2,NFE2L2,PLTP,MINDY2,SNRK,PTPRB,PTPRG,RDX,SGK1,LIMS2,SLC14A1,THSD1,PLCB1,SYNE1,TEK,PLSCR4" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000_k2 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.05E-03 1.00E+00 4.20E-03 3.81E-02 8 22 "BACH1,TUBB3,LPAR4,MAPT,NNAT,SNRPN,ZIC1,PCBP4" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k2_200 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.05E-03 1.00E+00 4.20E-03 3.81E-02 15 61 "PKP4,BACH1,RBM39,ZC3H11A,EDNRA,EIF4G1,EPB41L2,SMC2,LPAR4,CHIC1,TMLHE,TET1,ZC3H13,SSBP2,ADAMTS9" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.05E-03 1.00E+00 4.20E-03 3.81E-02 15 61 "VAT1L,TTLL9,CA4,CBLN1,CNTFR,FAM169A,GREB1,PIPOX,NLGN3,NKAIN4,CCDC40,FIGN,STK32B,PBLD,RBFOX3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.06E-03 1.00E+00 4.22E-03 3.83E-02 9 27 "CRMP1,CLIP3,NSG1,ACOT7,TAGLN3,SLC10A4,PRPH,SST,UCHL1" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.06E-03 1.00E+00 4.22E-03 3.83E-02 9 27 "VAT1L,CADPS,EYA1,TUBB3,IGSF5,STMN2,NEFM,RTN1,CUX2" Coexpression Atlas GSM854237_500 "Myeloid Cells, DC.103+11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103+ F4/80-lo, Small Intestine, avg-4" "Immgen.org, GSE15907" 1.07E-03 1.00E+00 4.25E-03 3.85E-02 58 375 "FMNL2,ALCAM,SEMA7A,FGD2,CASK,TMEFF1,ATP1A3,ADAM23,ST3GAL5,CD86,B4GALT6,FAM189A2,LY86,CSF1R,CSF2RA,CST3,CYBB,DOCK4,MYADM,DAPK1,EBI3,PLXNC1,DENND4A,IGSF6,FGFR1,TMEM107,GATM,GCNT2,MALT1,HPGDS,RAB30,ZNF496,GSN,SLC2A6,LRRC25,ITGAM,KHK,KIT,LIFR,AFDN,NCF2,NUCB2,PLTP,PILRA,RASGEF1B,ROGDI,LRRK2,RTN1,CCDC88A,ZNF667,ITPRID2,SULF2,ADGRL3,TIAM1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.07E-03 1.00E+00 4.25E-03 3.86E-02 29 155 "APOC2,SPTBN4,ZFYVE28,ARRB2,PDE8B,ATP1A3,BARD1,ZNF599,GPC2,IL33,KCNAB3,CCPG1,VAX2,CRYBB1,PTK2B,HPCAL4,ZMYND15,ABLIM2,NTNG2,ICA1,KNDC1,SCIN,GPR155,TCEAL5,PDE4D,STRC,DUSP15,SAMSN1,DNAH10" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.07E-03 1.00E+00 4.25E-03 3.86E-02 29 155 "KDM5D,AMH,GAS7,CADPS,MAGED1,SCRN1,DTNA,MAMLD1,MRO,PLXNC1,ERBB4,FAM198B,PTK2B,FGF13,FYN,GATM,PPARGC1A,GPR37,MOV10,PGAM2,RASGEF1B,PRKCB,MASP1,ROBO1,GLDN,MRAS,THRA,BEX4,ADAMTS9" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K5 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.08E-03 1.00E+00 4.28E-03 3.88E-02 52 328 "ZNF608,APOC1,ARRB2,TMEM108,TTLL9,BCHE,ARHGEF1,LRRFIP1,CBARP,CLCN3,ZNF385A,AKAP12,LRRC3B,CHRDL1,STX2,NCALD,RRAGB,FGF11,NOP56,SYT3,COQ5,CSDC2,KIAA1958,GPD2,GRIK5,LRRC75A,SHISAL1,SLC35G1,CDH20,KIT,IGSF11,SNX10,PMP22,MAGEL2,FSD1,NKAIN4,RELN,PTPN13,CEP97,SUSD4,STK32B,PTGR2,SALL1,MAPK12,CCDC92,SNRPN,LARP4,KANK1,OBSL1,DCBLD1,TST,CCDC14" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k2 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.08E-03 1.00E+00 4.28E-03 3.88E-02 42 251 "SPARCL1,ATP2A2,MYOM1,NRP2,CACNB4,AKAP5,MYADM,DMPK,CPEB2,DTNA,ABCC5,ELN,PRKAG2,FHL1,FLNC,IGSF5,FERMT2,PRUNE2,TPPP,BVES,IL6ST,NPTX2,PDE4B,PDE4D,SCHIP1,PRKCB,RYR3,STUM,SH3BGR,FHOD3,LIMS2,FNBP1,DBNDD2,ENHO,TNS1,RASD2,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,MSRB3" Coexpression Atlas GSM777059_500 "Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4" "Immgen.org, GSE15907" 1.08E-03 1.00E+00 4.28E-03 3.88E-02 66 439 "FMNL2,ADGRF5,SEMA6A,LTBP4,CDC42BPA,SEMA7A,NRP2,IL33,CA8,LDB2,B4GALT6,SLIT2,FAM189A2,ZNF521,CDC42BPB,SNCAIP,CSF1,ARHGEF10,PLXNA4,DOCK4,ARMCX4,RCAN1,ARRDC4,ECM2,EDN1,EDNRB,SEMA3D,TMTC1,ELN,CALCRL,F8,ARMCX1,DLC1,FCGRT,ST6GALNAC3,LYVE1,FERMT2,GUCY1A1,ICA1,LIFR,MEIS2,MSR1,NPR2,CLDN11,ENPP2,PLCD1,PMP22,RELN,PTPRB,RGS4,ROBO1,PEAR1,SH3GL3,BTBD3,UNC5B,RGL1,KLHL4,DOCK9,TNS2,TEK,TIMP4,NPL,FLRT2,NPDC1,ADAMTS9,MSRB3" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k2_500 kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.08E-03 1.00E+00 4.29E-03 3.89E-02 28 148 "PCDH19,VAT1L,BARD1,BCL7A,CACNA1G,SLIT2,CENPL,GSDME,SV2B,RAB39B,HSD17B14,MTHFD2,IGSF5,KDM2B,CLEC18A,TM6SF1,MSI1,NPY,ROBO1,GLDN,CNKSR2,SOX11,TACR1,CUX2,HEY1,SLC38A1,ADAMTS9,FZD3" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_k1_1000 kidney_adult_Mesangium_Meis_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.09E-03 1.00E+00 4.31E-03 3.91E-02 25 127 "OSBPL8,C1QTNF1,CDC42BPA,ARRB1,CLOCK,CEP85L,ST3GAL6,GGT5,FERMT2,RASSF8,ZHX1,IL6ST,GPR155,MAPT,CCSER2,PKIA,PTH1R,FAM184A,ZDHHC14,CPEB4,LMBRD1,TNS2,FRYL,PLEKHH2,SPIRE1" Coexpression Atlas ratio_EB_vs_SC_1000_K1 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 1.09E-03 1.00E+00 4.32E-03 3.91E-02 53 336 "NCKAP5,ADRA1B,KCTD16,INSYN2B,THSD7A,SLIT2,ABI3BP,CRHBP,ARHGAP24,DLX1,EBF1,EDN1,MBNL2,CERCAM,NRN1,FAM198B,DLC1,FOXF2,GGT5,DCLK2,GPER1,ATOH8,IL6ST,SMAD9,GPR155,MEIS1,MEIS2,SAMD5,RTL5,NFIX,GPR85,PMP22,RELN,PTPRH,RIPOR1,FAT4,ENOX1,MORC4,RGS4,TNFRSF19,PEAR1,CCDC92,CABCOCO1,ITPRID2,ZEB1,TMEM121,ZFPM2,RP9P,HEY1,TLR4,FLRT2,PRDM8,MSRB3" Coexpression Atlas PCBC_ratio_MESO-5_vs_MESO-15_cfr-2X-p05 Mesoderm Day 5_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.11E-03 1.00E+00 4.39E-03 3.98E-02 168 1302 "KCNH8,SYS1,ACTN1,AXIN2,PWWP2A,ZNF608,PCDH10,ANK2,APC,LGR5,TMEFF1,ARHGDIG,MARK4,ATP1B3,KIF1A,ADGRB2,CFLAR,BMP7,NAE1,MTMR2,GPC2,CALB1,CBR1,CBS,USP2,CDH2,ZMYM4,LRRFIP1,LRWD1,CACNA2D2,CBARP,FAM189A2,COL9A3,TBPL1,LRIG1,PPP1R16B,PLCXD3,ARHGEF4,MYADM,ARHGAP24,KIF26A,LONRF1,DAPK1,AIF1L,DBN1,NR1D2,DTNA,E2F5,PCOLCE2,PAN3,EPB41L2,RCAN2,ERBB4,RASL12,CD320,REEP2,NSRP1,TUBB3,SCML2,POLR1B,FGF13,FGFR1,RGPD5,CAMKK2,CELF1,STAU2,GAA,GABRB3,MTHFD2,GDF1,RNPS1,CBX1,KDM2B,GNAL,FERMT2,GPR37,TMEM121B,GRB10,ZNF496,PSIP1,SLC2A6,FAM222A,RASSF8,HAS2,ACOT7,IGFBPL1,ZIC5,LRRCC1,C2CD4C,ITPKB,KCNF1,KIT,IPO5,L1CAM,STMN1,MSANTD3-TMEFF1,MATN3,NBL1,NRCAM,CLDN11,SEMA5B,PKM,GPSM2,JAKMIP1,STRN3,LRP12,FSD1,GDPD1,PSMA6,PTPN13,FAM184A,RBBP8,NUDT11,LGI2,ZNF532,MRAP2,MCMBP,TCP11L1,PLPPR3,SALL1,ATXN7,HES6,SH3BGR,ANKRD6,BTBD3,SLC6A8,RADIL,SLC9A5,TET1,SMARCD3,RCOR3,SNRPN,DBNDD2,MCF2L2,ST5,NUDT10,TMEM150C,DNMBP,AGTPBP1,TRIM2,USP22,FAM189A1,SIRT1,GALNT17,TMPO,FAM124A,PIK3R5,RGMB,TRPM2,CA14,TUBB2A,RPRM,UCHL1,VLDLR,CLIP2,KCNK12,ZIC2,NDRG4,ZNF138,ANKS1B,SMARCAD1,MEIS3,SLC38A1,JMJD1C,NETO2,SOCS4,LAS1L,JPH3" Coexpression Atlas GSM854243_500 "Myeloid Cells, DC.103+11b-.LuLN, MHCII+ CD11c+ CD8- CD11b- CD103+, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.14E-03 1.00E+00 4.49E-03 4.07E-02 58 376 "FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,LY86,SLC4A8,CSF1,CST3,MYADM,PLPPR4,ARRDC4,PLXNC1,RASA4,ENO2,MTSS1L,ZMYND15,MTHFD2,RAB30,ADAP1,SLC2A6,HSF2,SCIN,INSM1,JAK2,NCOA7,ASPRV1,PFKFB3,CCSER2,ROGDI,ZDHHC14,RGS12,SEMA6D,ARHGEF40,CCDC88A,SAMSN1,SSPO,STXBP1,ARHGEF9,TMEM150C,ARC,PHF24,SLC44A1,TRPS1,ZBTB38,SPIRE1,ITM2C" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k3_500 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.14E-03 1.00E+00 4.50E-03 4.08E-02 31 170 "ADORA2A,ADAM15,NRP2,ARHGEF7,CD38,LY86,HAPLN1,CSF1R,CYBB,PITPNC1,EBF1,EDNRB,CALCRL,PDLIM5,FYB1,GGTA1P,HPGDS,LPAR4,ICA1,MEF2C,PDE4B,SNRK,PTPRB,SGK1,PREX2,BTBD3,LIMCH1,THSD1,KLHL4,TEK,WIPF1" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_1000 kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.14E-03 1.00E+00 4.50E-03 4.08E-02 108 787 "KCNH8,KLHL32,PCDH19,SEMA6A,LRCH2,LCORL,LGR5,BARD1,BCL7A,BLM,PROM1,BMPR1B,NAE1,CA8,CALB1,CD38,CRLF1,RCBTB2,B4GALT6,SLIT2,HAPLN1,FAM169A,CTH,CENPL,GSDME,RAB39B,DUSP9,E2F5,EDNRB,SEMA3D,PLEKHA1,STARD3NL,EMX2,RRAGB,SH3YL1,ACSL4,FDFT1,SPSB4,FHL1,NOP56,SMC2,UFM1,FAM49B,MTHFD2,IGSF5,PPARGC1A,DBF4,RAB30,CBX1,MAP7D2,KCNMB4,LPAR4,HAS2,ZDHHC15,JAK2,KCNJ16,KIT,LIG4,LMO2,GPR155,KITLG,SAMD5,MSI1,THYN1,TCEAL5,PRTG,GPSM2,PCDH18,SEPT4,GDPD1,LAMA1,PTH1R,SPDL1,ZIK1,EML5,TMEM255A,RADX,RET,MORC4,FIGN,NUDT11,ROBO2,TRAPPC13,FHOD3,CNKSR2,PREX2,SNRPN,SOX11,ZC4H2,NUDT10,TMEM150C,TAF9,KLHL4,CUX2,TEK,C18orf54,ITGB3BP,BEX4,STXBP4,TRPS1,CA14,UCHL1,VLDLR,VSNL1,ZFP37,SLC38A1,NHSL1,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.15E-03 1.00E+00 4.53E-03 4.10E-02 17 74 "PCDH10,DPP10,LDLRAD4,CH25H,CNR1,SLC35F1,DLX1,FGF13,UBE2E3,FOXF2,PPARGC1A,MARK1,MAPK10,ROBO1,ANKRD6,CXXC4,RPRM" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.15E-03 1.00E+00 4.53E-03 4.10E-02 11 38 "PCDHGB4,CNTN1,DBI,EDNRB,ETV1,LUZP2,SHC3,NKAIN4,PTN,S100B,SIRT2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.15E-03 1.00E+00 4.53E-03 4.10E-02 11 38 "PCDHGB4,CNTN1,DBI,EDNRB,ETV1,LUZP2,SHC3,NKAIN4,PTN,S100B,SIRT2" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k5 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.15E-03 1.00E+00 4.53E-03 4.10E-02 11 38 "CALB1,COL9A1,CRYM,TVP23A,HAS2,MEIS1,PCDH8,SNCA,CUX2,ENHO,NETO2" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_500_k2 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.17E-03 1.00E+00 4.58E-03 4.15E-02 22 107 "EPB41L5,CD38,ARHGAP24,RASGRP2,EPHB1,ST3GAL6,FLT1,CGREF1,IGSF5,PCDH17,HP,TM6SF1,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,FAM81A,DDN,STX1A,TMEM150C,TMEM178A" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype MyoFB-A(1) Lungmap Mouse Lung PND3 MatrixFB Subtype MyoFB-A(1) Lungmap CCHMC 1.18E-03 1.00E+00 4.61E-03 4.18E-02 45 275 "AGT,C1QTNF3,LTBP4,ATP2A2,DDR1,CNN3,ARHGEF6,CNTFR,MAGED1,VCAN,SOCS5,E2F5,EDNRB,ELN,TUBA1B,BRD8,STARD3,FERMT2,FUT10,STMN2,BACH2,DHX35,MT1M,NFIX,PDE3A,FXYD1,PMP22,PTN,FAM184A,FIGN,RIC8B,PBRM1,MEG3,SEC14L1,NAPB,PDZRN3,CAMTA2,TCF4,PCDHGA9,CRTC1,TEK,TIMP4,TPM1,UCHL1,TUBA1A" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k5 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.20E-03 1.00E+00 4.68E-03 4.24E-02 23 114 "SFMBT2,ADAM23,MPDZ,COL9A1,CRMP1,TMCC2,GRIN3A,SPEG,KCNMB4,GP1BB,STMN2,LINGO1,INSM1,MEIS1,TAGLN3,NTRK2,PCDH8,DIRAS2,PTX3,SLC9A5,THSD1,TAL1,CUX2" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_k4_1000 kidney_P4_CapMesRenVes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.20E-03 1.00E+00 4.68E-03 4.24E-02 23 114 "ADCY6,TMEM108,CACNA2D2,KIAA0040,ARHGAP24,AIF1L,ST3GAL6,PARD3B,GUCY1B1,GPR155,MAT2A,MYO6,NELL2,PLXNB1,SEPT4,PTN,PTPRO,FAM184A,DUSP15,TMEM150C,PLEKHH2,SPIRE1,SPATA13" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k2_1000 kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.20E-03 1.00E+00 4.68E-03 4.24E-02 23 114 "CACNA2D1,KIAA0040,USP6NL,SCRN1,ST3GAL6,TRIM16,KHDRBS3,GUCY1B1,GPR155,MAT2A,MYO6,NFIX,PLXNB1,PMP22,PKIA,PTN,PTPN13,SLC12A2,KIF13A,PDZD2,TMEM150C,PLEKHH2,SPATA13" Coexpression Atlas ratio_ECTO_vs_SC_500_K1 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 1.21E-03 1.00E+00 4.71E-03 4.27E-02 46 283 "ABHD6,LGR5,LINC00173,CA4,NOG,LHX2,CNTFR,NRG2,SEC31B,HAPLN1,BOC,LYPD1,EMX2,NCALD,CLVS1,TPPP3,GPR162,ZNF491,INSM1,CLEC18A,MAP2,MAP6,MEIS2,TAGLN3,RTL5,NPY,PAX6,PRTG,ENPP2,SDK2,ZFHX4,KLHDC8A,MELTF-AS1,ARX,DMRTC1,CLSTN2,SSPO,NR2E1,RIMBP2,ZIC1,EMX2OS,CRB2,MKRN3,DPYSL5,ADAMTS9,FAM182B" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_ureter_1000_k1 DevelopingLowerUrinaryTract_adult_ureter_emap-29479_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.21E-03 1.00E+00 4.71E-03 4.27E-02 28 149 "MTUS1,ADGRF5,SEC11C,GPR146,CAST,ENTPD2,ABI3BP,KIAA0040,MFAP3L,NR1D2,SLC12A6,NRN1,FGF1,GALNT15,GCNT2,ADAM28,LYVE1,GSN,FAM107A,HNMT,MBP,ABCB1,SCN7A,HSPA4L,SLC14A1,SLC44A1,TLR4,AGMO" Coexpression Atlas gudmap_developingKidney_e15.5_1000_k1 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.22E-03 1.00E+00 4.75E-03 4.31E-02 27 142 "BEND6,TNRC6C,CACNA2D1,CFL2,GOLT1B,SYNCRIP,SMC2,PDLIM5,RAPGEF6,ZHX1,LIMS1,CHIC1,MEIS1,MKLN1,CNTN3,ENPP2,RASGRF1,ZFP2,FAM126B,ZHX3,NEK4,ARHGEF9,VPS13A,ERCC6L2,RGMB,MSRB3,SOCS4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.25E-03 1.00E+00 4.85E-03 4.40E-02 12 44 "CALB1,PLXNA4,DOCK4,DRP2,EMX2,KCND2,KLHL23,MATN2,PCDH18,ADGRL3,ZFPM2,ACTR6" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_100_k3 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.25E-03 1.00E+00 4.85E-03 4.40E-02 12 44 "PCDH19,DOC2A,GREB1,PSD2,PRDM5,CLEC18A,MID1,NPY,OXTR,PRTG,EMID1,HEY1" Coexpression Atlas PCBC_ratio_MESO-5 blastocyst_vs_MESO-5 amniotic fluid MSC_cfr-2X-p05 MESO-5 blastocyst_vs_MESO-5 amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.25E-03 1.00E+00 4.88E-03 4.42E-02 82 572 "KCNH8,SYS1,AXIN2,APC,APOC1,LGR5,ARHGDIG,ARRB1,ARSE,RASL11B,NRP2,CFLAR,JAZF1,C5,GPC2,CBR1,USP2,CRMP1,PPP1R16B,PLCXD3,ARHGEF4,MYADM,LYPD1,DTNA,EDNRA,CERCAM,ERBB4,CAMKK2,HRASLS5,GABRB3,FREM1,GNAL,GPT2,GPR37,TMEM121B,GRB10,SLC2A6,FAM222A,IGFBPL1,HP,IL6ST,KCNF1,KIFC3,AFF1,NRCAM,GNG2,SEMA5B,PKM,GPSM2,JAKMIP1,PRKAB2,GDPD1,ELOVL2,CASTOR1,ACSS3,SEMA6D,GALNT10,SH3BGR,ANKRD6,SLC9A5,SMARCD3,FAM219A,DBNDD2,MCF2L2,NFASC,ST5,SULF2,TMEM150C,KLHL4,GALNT17,FAM124A,PIK3R5,TRPM2,RPRM,VLDLR,CLIP2,KCNK12,ZIC2,NDRG4,ANKS1B,PCBP4,CASC15" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.26E-03 1.00E+00 4.88E-03 4.43E-02 18 81 "KLHL13,PPP4R4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,MTSS1L,KLHL23,KITLG,SERPINI1,RASA3,SLC4A3,KDM3A,ADGRL3,ACTR6" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_HindBrain_100 e8.5_NeuroEpith_HindBrain_top-relative-expression-ranked_100 FaceBase_ST1 1.26E-03 1.00E+00 4.88E-03 4.43E-02 18 81 "FZD9,VAT1L,CA4,CBLN1,CLDN10,SOCS6,CNTFR,SCRN1,IP6K1,PIPOX,REEP2,UBE2QL1,ELOVL5,ICA1,NKD1,AQP11,ELOVL2,ACTR3B" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500_k4 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.26E-03 1.00E+00 4.88E-03 4.43E-02 18 81 "JAZF1,ABI3BP,GSDME,PLXNC1,GATM,AIFM3,MAP7D2,SHISA6,KIT,NEXMIF,ABCB1,MAPK10,GDPD1,CPEB3,SYNE2,ANKRD12,RASD2,NDRG4" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k4_1000 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.26E-03 1.00E+00 4.89E-03 4.43E-02 15 62 "BACH1,CALB1,RUNX1T1,HAPLN1,ALKBH8,EMX2,MEX3B,LPAR4,CHIC1,MEIS2,ZKSCAN3,SULF2,KLHL4,ASXL3,STXBP4" Coexpression Atlas geo_heart_1000_K2 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 1.28E-03 1.00E+00 4.94E-03 4.48E-02 49 307 "NDRG2,GALNT16,C1QTNF1,ADGRF5,SPARCL1,FGD2,PLA2G4C,AZGP1,DNAJC27-AS1,GPR146,CABP1,NRN1,ABCA8,FCGR3A,CHL1,GALNT15,HIGD1B,ALDH1L1,CSDC2,GGTA1P,GGT5,LYVE1,LILRB4,GSN,FAM107A,INSYN1,VSIG4,ALDH1L1-AS2,IGF1,ITGA7,ITGAM,PACRG,DUSP26,SEPT4,PPP1R1A,PTH1R,PTPRB,SUSD4,PRIMA1,RNASE1,MRAS,SH3BGR,ABLIM3,SLC11A1,COBL,HIF3A,RASD2,LGI4,SLC30A3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.29E-03 1.00E+00 5.00E-03 4.53E-02 30 164 "ADCY5,MYOM1,NRP2,CACNA2D1,DMPK,CPEB2,MRVI1,IGSF5,PRUNE2,BVES,HNMT,IFI16,IL6ST,NPTX2,PRKCB,RYR3,SCN7A,STUM,SH3BGR,FHOD3,LIMS2,DBNDD2,ENHO,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,ACTR3B,MSRB3" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000_k3 DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.29E-03 1.00E+00 5.00E-03 4.53E-02 58 378 "ABCF1,ADD1,AP2A2,TBC1D14,AK2,TAOK1,OGT,PRMT9,CALM1,CAMK2G,RUNX1T1,CCNT1,ARHGEF1,RBM39,RNF14,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,SACS,DNM1L,EPB41L2,FGFR1,AHDC1,GRB10,GUCY1B1,KIF2A,MAPT,NNAT,PCDH18,EXOSC10,PRKACB,MRPS18A,MEG3,SEC14L1,SMARCA4,SNRPN,RBM26,SPART,TROVE2,SYNE2,PJA1,FBXW11,PUM2,TMPO,TPM1,USP1,ZNF142,ZFAND5,INTS3,STOX2,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas GSM538277_500 "Myeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.30E-03 1.00E+00 5.01E-03 4.54E-02 59 386 "ACTN1,FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,LY86,SLC4A8,ABCG1,PNPLA8,RUBCN,RASSF2,PLXNC1,RASA4,CALCRL,ENO2,ZMYND15,MALT1,RAB30,ADAP1,SLC2A6,HSF2,SCIN,INSM1,JAK2,KTN1,ASPRV1,ADAM11,MYO5A,NPR2,PFKFB3,CCSER2,PLCL1,ROGDI,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,ST5,SULF2,ARHGEF9,TMEM150C,ARC,PHF24,SLC44A1,SYNPO2,SPIRE1,NETO2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.30E-03 1.00E+00 5.03E-03 4.56E-02 43 261 "MTUS1,SPARCL1,LARGE1,SLIT2,CRHBP,VCAN,CST3,PLCXD3,BRINP1,GRIN3A,DRP2,EDNRA,TMTC1,EGFR,LRRC17,RACK1,FREM1,ADAMTS6,IGF1,MATN2,MEIS1,MEIS2,MMP16,NTRK2,ENPP2,PFKFB2,PCDH18,PMP22,NKAIN4,MASP1,PTN,TMEM255A,C1orf54,FAT4,LGI2,ROBO2,HUNK,SULF2,ADGRL3,TEK,ASXL3,VLDLR,ADAMTS9" Coexpression Atlas gudmap_developingGonad_P2_epididymis_200 DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.32E-03 1.00E+00 5.09E-03 4.61E-02 29 157 "ADCY8,C1QTNF3,ARHGAP20,PKP4,BACH1,RGN,DCLK1,RBM39,MFAP3L,ZC3H11A,CHRDL1,EDNRA,EIF4G1,LRRC17,GAD1,GLUL,LPAR4,CHIC1,MEIS2,NFIX,NALCN,TMLHE,MRAP2,MEG3,ARX,SYNE2,PCDHB9,CBX5,SSBP2" Coexpression Atlas PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05 Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.34E-03 1.00E+00 5.16E-03 4.68E-02 53 339 "ADCY6,APOC1,LGR5,IGDCC4,ARHGDIG,BMP7,ST3GAL5,C5,MYRF,USP2,CBARP,PLEKHB1,HOMER3,COL9A3,ENTPD4,VCAN,CST3,PLCXD3,ARHGAP24,EDNRA,HSD17B14,ERBB4,RASL12,FGFR3,GALC,GDF1,MRPS31P5,FAM222A,HAS2,IL6ST,KIFC3,LIFR,MAN2A2,NRCAM,PRTG,PRKAB2,RELN,LAMA1,RIPOR1,FAM184A,LGI2,MRAP2,EMID1,PLPPR3,SALL1,TNFRSF19,ANKRD6,RCOR3,DNMBP,FAM189A1,GPR161,TTC3,ADAMTS9" Coexpression Atlas GSM777050_500 "Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5" "Immgen.org, GSE15907" 1.35E-03 1.00E+00 5.18E-03 4.70E-02 69 467 "NDRG2,GALNT16,SPARCL1,SRPX,LTBP4,NRP2,SGCE,IL33,THSD7A,ARHGEF25,ENTPD2,DCLK1,CNTFR,MAGED1,ABI3BP,CLIP3,CSF1,BOC,ARHGAP24,DAPK1,CHRDL1,ECM2,EBF1,EGFR,PCOLCE2,ELN,DLC1,FCGRT,FGFR1,AMOTL2,SCARA3,TPPP3,GAA,GABRA3,GFRA2,FERMT2,STMN2,GRB10,GSN,GSTM5,GUCY1A1,LAMA2,LIFR,MATN2,MEIS1,MEST,NBL1,NFIX,NPR2,PDE3A,ENPP2,FXYD1,PLTP,PMP22,EPDR1,PTPRG,KIRREL1,RTN1,SCN7A,PKNOX2,ST5,TNS2,CSMD1,SYNPO2,PLEKHH2,NPDC1,AGMO,SEMA3B,MARCH8" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.35E-03 1.00E+00 5.19E-03 4.70E-02 17 75 "AMPH,EPB41L5,VAT1L,CASK,CDH2,CRYM,EYA1,DENND2A,FAM19A2,FAM107A,HAS2,LSAMP,MEIS2,SALL1,CSRNP3,ANKRD6,NETO2" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k3_200 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.38E-03 1.00E+00 5.30E-03 4.81E-02 7 18 "TUBB3,STMN2,INSM1,MAPT,NEFM,GNG2,PCBP4" Coexpression Atlas GSM538274_500 "Myeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.38E-03 1.00E+00 5.31E-03 4.81E-02 62 411 "FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,ABCD2,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,LY86,SLC4A8,GDA,PNPLA8,RASSF2,DNM1L,PLXNC1,RASA4,ENO2,ZMYND15,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,IRAK3,HSF2,INSM1,JAK2,KTN1,ASPRV1,ADAM22,MYO5A,NPR2,PFKFB3,CCSER2,PLCL1,ROGDI,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,ST5,SULF2,ARHGEF9,TMEM150C,ARC,SLC44A1,SYNPO2,TRPS1,SPIRE1,SLC30A4" Coexpression Atlas GSM399373_500 "alpha beta T cells, T.4SP24int.Th, 4+ 8- TCRhi 24int, Thymus, avg-3" "Immgen.org, GSE15907" 1.40E-03 1.00E+00 5.39E-03 4.89E-02 51 324 "ACTN1,NDRG2,ADCY6,AXIN2,ARHGAP20,PITPNM2,SFMBT2,GPR146,SYNJ2,CNN3,LRIG1,SIPA1L1,PPP1R16B,CDON,RASGRP1,TNK2,TMEM35A,TLR7,TMEM164,FYN,CHL1,KCNMB4,GSN,ADAMTS6,BACH2,ZDHHC15,ITPKB,KCNH2,STMN1,ZNF827,PDE4D,TMIE,SLC25A23,PPM1B,ZSCAN2,BEND5,RGS3,SATB1,ZNF821,GALNT10,FAM102A,ST6GAL1,DZIP1,ST8SIA1,TET1,PJA1,BHLHB9,RUNDC3B,SSBP2,TTC3,TUBA1A" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.40E-03 1.00E+00 5.39E-03 4.89E-02 36 209 "ADCY8,KIAA1324,ARHGAP20,PDE8B,ADGRB2,BARD1,LDLRAD4,CAMK2A,KCNAB3,CSF1,CSF1R,DRP2,SNX29,RASA4,FYB1,TMEM8B,LYVE1,GNG4,KLHL23,GPR155,NPR2,PLCL1,TRHDE,PRKAR1B,MASP1,DEF8,ZCWPW1,ZNF493,ZMAT4,STK32B,MRAS,ASAP3,FAM189A1,EML6,CADM2,DPF3" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K4 facebase_RNAseq_e10.5_Emin_LatNas_2500_K4 Gudmap RNAseq 1.43E-03 1.00E+00 5.48E-03 4.97E-02 16 69 "PCDH19,DOC2A,BMPR1B,DUSP9,EMX2,FGF12,FRMD5,MAPK4,NKAIN1,NUDT11,GLDN,SOX11,TMEM150C,BEX4,LYPD6,ANKS1B" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k5_200 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.43E-03 1.00E+00 5.48E-03 4.97E-02 16 69 "LCORL,BACH1,RUNX1T1,SLIT2,RBM39,TCAF1,SMC2,LPAR4,CHIC1,MEIS2,MMP16,TMLHE,CPEB4,CBX5,SSBP2,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.46E-03 1.00E+00 5.59E-03 5.06E-02 11 39 "SYT13,SEPT7,NSG1,STMN2,BEX5,RTN1,SNAP25,PEG10,VGF,CELF4,REEP1" Coexpression Atlas Lungmap Mouse Lung E16.5 Myeloid Subtype Mature Myeloid Lungmap Mouse Lung E16.5 Myeloid Subtype Mature Myeloid Lungmap CCHMC 1.46E-03 1.00E+00 5.60E-03 5.07E-02 63 420 "C3orf14,RNF150,ADRB2,BIN1,PKP4,ATP6V0A1,GPR146,CD86,MS4A7,CLTC,LY86,ARHGEF6,SH2B1,HINFP,CRYBB1,GAPVD1,PITPNC1,TOM1,SLC43A2,TLR7,EXTL2,TAOK3,FCGR1A,FCGRT,SEMA4D,ANKFY1,FYB1,GAA,GALC,IQGAP2,ACSS1,GATM,SESN1,HPGDS,GPR34,IGF1,LMO2,LYPLAL1,TM6SF1,MEF2C,MID1,MT1M,MYO5A,MYO7A,TREM2,SH3KBP1,PTPRO,ROGDI,MSANTD2,RNASEL,ADAL,ST6GALNAC6,FNIP1,CHD9,ST6GAL1,SLC11A1,FNBP1,SIN3B,NPL,WBP2,TRPM2,P2RY12,TFIP11" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_500_k4 DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.47E-03 1.00E+00 5.61E-03 5.08E-02 37 217 "USP31,ADGRF5,NRP2,CA8,CD38,MAP4K4,LY86,RBM39,PPP1R16B,CYBB,ELMO1,SEZ6L2,EDNRB,DLC1,FLT1,PCDH17,LYVE1,NCKAP1L,ICA1,IRF8,MEF2C,MEIS2,MSR1,MYO7A,PTPRB,TMEM255A,MAPK12,SGK1,PREX2,SAMSN1,THSD1,TAL1,KLHL4,ARHGAP9,WIPF1,PLD4,RGS7BP" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k3 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.50E-03 1.00E+00 5.73E-03 5.19E-02 15 63 "CADPS,CNTN1,CNRIP1,EPB41L2,MRVI1,HAS2,NEGR1,LAMA2,MEIS1,MMP16,CLDN11,PTX3,ZFPM2,TPM2,SYNPO2" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_k2_500 kidney_adult_RenCorpuscGlomer_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.53E-03 1.00E+00 5.83E-03 5.28E-02 23 116 "HECW2,ADGRF5,PI16,CD38,CLTB,EDNRB,TMTC1,CALCRL,F8,DLC1,FLT1,INPP5K,STMN2,LIFR,LMO2,SNRK,PTPRB,SCN7A,SGK1,PLCB1,SYNE1,TEK,PLSCR4" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-OSK-L-l-p53KD_cfr-2X-p05 Mesoderm Day 30-reprogram_NA_vs_Mesoderm Day 30-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.53E-03 1.00E+00 5.83E-03 5.29E-02 36 210 "ARSE,ATP1A3,GPC2,ARHGAP33,LARGE1,CDO1,LHX2,AKAP7,CRMP1,LYPD1,KHDRBS3,TOX3,GNG4,LINGO1,IGFBPL1,KCNJ16,KIF5A,L1CAM,PIK3AP1,MAPT,NELL2,GNG2,SEMA5B,RELN,PTN,NKAIN1,PRRT2,RTN1,HES6,HKDC1,SLC12A2,SOX11,SST,SEPT3,ZIC2,DPYSL5" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-episomal_cfr-2X-p05 Mesoderm Day 30-method_NA_vs_Mesoderm Day 30-method_episomal-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.53E-03 1.00E+00 5.83E-03 5.29E-02 36 210 "ARSE,ATP1A3,GPC2,ARHGAP33,LARGE1,CDO1,LHX2,AKAP7,CRMP1,LYPD1,KHDRBS3,TOX3,GNG4,LINGO1,IGFBPL1,KCNJ16,KIF5A,L1CAM,PIK3AP1,MAPT,NELL2,GNG2,SEMA5B,RELN,PTN,NKAIN1,PRRT2,RTN1,HES6,HKDC1,SLC12A2,SOX11,SST,SEPT3,ZIC2,DPYSL5" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K4 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.56E-03 1.00E+00 5.92E-03 5.37E-02 41 248 "TMEM108,TTLL9,BCHE,CA4,CA12,CBLN1,CCNT1,ARHGEF1,LRRFIP1,CLCN3,LRRC3B,CHRDL1,NCALD,PIPOX,FGF11,NOP56,SYT3,COQ5,CSDC2,GRIK5,SHISAL1,CDH20,IGSF11,PRTG,SNX10,PLTP,PMP22,MAGEL2,FSD1,NKAIN4,RELN,GDPD2,PTPN13,STK32B,PTGR2,SALL1,SNRPN,MTCL1,BEX4,CCDC14,ZIC2" Coexpression Atlas gudmap_kidney_e15.5_Podocyte_MafB_500 kidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.56E-03 1.00E+00 5.92E-03 5.37E-02 62 413 "ALCAM,EPB41L5,ASPA,SLC4A4,BCL7A,PROM1,IL33,CA4,CA8,CACNA2D1,CALB1,CLDN10,SNCAIP,VCAN,CTH,ARHGAP24,SEMA3D,LRRC17,ERBB4,EYA1,ST3GAL6,UFM1,FUT9,IQGAP2,IGSF5,FREM1,GHR,PPARGC1A,PARD3B,HAS2,NEGR1,KCNJ16,TM6SF1,MYO6,NELL2,NME4,NOVA1,ENPP2,DRAM2,MINDY2,LAMA1,PTN,PTPN13,PTPRO,PTX3,FAM184A,SUGCT,ROBO2,SALL1,CPEB4,NUDT10,PLCB1,TMEM150C,KLHL4,CUX2,NPL,TRPS1,UGT8,PLEKHH2,VLDLR,KCNT2,ADAMTS9" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.57E-03 1.00E+00 5.96E-03 5.40E-02 13 51 "HECW2,QKI,HAPLN1,ELMO1,ST3GAL6,FYN,ABCB1,ZNF532,SEMA6D,FAM102A,PEG10,HEY1,NHSL1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k3_200 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.57E-03 1.00E+00 5.96E-03 5.41E-02 17 76 "ARHGAP20,MYRF,CBLN1,CNTFR,VCAN,EDNRA,FLNC,FREM1,GHR,GUCY1A1,GUCY1B1,MATN2,MEIS1,NEFM,PCDH18,PTN,ROBO2" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k3_500 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.57E-03 1.00E+00 5.96E-03 5.41E-02 17 76 "CACNA2D1,ARHGEF6,DGKB,EBF1,FRY,RCAN2,RASGRP2,GUCY1A1,GUCY1B1,MARK1,PDE3A,SERPINI1,FXYD1,ZDHHC14,SLC8A1,SLC12A2,TNS1" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_100 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.57E-03 1.00E+00 5.96E-03 5.41E-02 17 76 "PCDH19,DOC2A,CA4,CRYM,GREB1,DUSP9,PSD2,GALC,PRDM5,CLEC18A,MID1,NPY,OXTR,PRTG,EMID1,SALL1,HEY1" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_1000_k2 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.57E-03 1.00E+00 5.96E-03 5.41E-02 33 188 "APBB2,EPB41L5,CCAR2,NRP2,CD38,CACNA2D2,LRIG1,ARHGAP24,TMCC2,RASGRP2,EPHB1,ST3GAL6,FLT1,CGREF1,IGSF5,PCDH17,PARD3B,HP,LIFR,TM6SF1,RETREG1,SCHIP1,MBOAT7,RELN,PTPRO,RIPOR1,ZDHHC14,FAM81A,DDN,STX1A,TMEM150C,ZNF23,GDPD5" Coexpression Atlas gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000 dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.58E-03 1.00E+00 5.97E-03 5.41E-02 111 820 "AXIN2,BRAP,USP31,ESYT2,MTA3,HACE1,HFM1,FAM135A,PARG,APOC2,USP37,CPNE5,PPP4R4,MADD,PLA2G4C,ZNF583,RNF182,ADAM23,BARD1,BLM,NAE1,SCAPER,PRMT9,RUNX1T1,MTMR7,LRBA,LONRF2,PLAA,C4orf33,FAM169A,DZIP3,RIMS2,FBXL5,NR1D2,CPEB2,CASP8AP2,DUSP9,DNAJB6,KCTD3,PLEKHA1,PCOLCE2,DENND4A,RRAGB,SCML2,MED12L,FGF13,PRKAG2,C2orf88,EFCAB2,CINP,ATP6V1H,TUBGCP4,DBF4,MAP7D2,DCLK2,TDRKH,COQ10A,DDX19B,HSF2,KIT,ADAM22,MYO9A,NEK1,NOVA1,TBC1D25,PRTG,GPSM2,C19orf57,PPP3CC,PPP5C,CEP41,PRPSAP2,BCAS3,EML5,ZCWPW1,RBBP8,CARF,CCDC25,FBXW7,MCMBP,ADAL,STX1B,FNIP1,KIF27,HSPA4L,SH3BGR,CNKSR2,CCDC92,TET1,ZNF667,GKAP1,DOP1A,TEX2,LARP4,ZSCAN29,VPS13A,ANKRD12,TAF6,DMXL2,SATB2,SIRT1,ERCC6L2,RUNDC3B,UGT8,SLC30A4,WNK3,PHTF2,ACTR3B,RNF170,AAAS,NETO2" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.59E-03 1.00E+00 6.03E-03 5.47E-02 35 203 "RALGAPA1,FAM135A,OGT,APC,PHYHD1,CACNA2D1,CFL2,DZIP3,CPEB2,KMT5B,EIF5,EIF1,MED12L,SUCO,SYNCRIP,SMC2,PDLIM5,KAT7,KIF2A,MKLN1,NEK1,CNOT4,PIK3C2A,KANSL1,DPF2,REV3L,TRA2B,CLASP2,PRRC2C,VPS13A,MGRN1,R3HDM1,RGMB,SSBP2,VLDLR" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K4 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.60E-03 1.00E+00 6.03E-03 5.47E-02 37 218 "KDM5D,CDK10,CA12,ARHGEF25,LDB2,CRLF1,PCYT1B,FAM149A,PITPNC1,CDON,DUSP9,EDNRA,SUGP2,ETV1,TMEM132C,ST6GALNAC3,ZNF276,KCNMB4,SYNPO,IGF1,LAMA2,MBNL1,SRSF12,NBL1,PCSK5,PDE3A,ZFHX4,RNH1,PREX2,LIMCH1,SULF2,TAF9,SZT2,ASXL3,TNS1,AMACR,CA14" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_nonFloorPlate_500_2 e8.5_NeuroEpith_nonFloorPlate_top-relative-expression-ranked_500_2 FaceBase_ST1 1.61E-03 1.00E+00 6.07E-03 5.50E-02 51 326 "LRCH2,CCNT1,SYNGR3,SOCS6,FAM19A5,ARMC8,BAG4,LRRC3B,FAM169A,YTHDC1,FBXL5,FOXO3,NOP56,B4GALNT1,GPR162,ZNF638,STMN2,PRDM5,RNF165,KAT7,UBE2QL1,ELOVL5,IGFBPL1,TCEAL6,ICA1,INPP1,KHK,IPO5,PACRG,TM6SF1,MIA2,MYCN,NOVA1,PMP22,EPDR1,SLC25A36,RPE,ADAL,TRAPPC13,SALL1,PPP4R3A,SNRPN,SPATA7,ELOVL4,ADAMTS17,TBL1X,CCDC173,STXBP4,PPIL6,TBC1D15,PDSS2" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k3 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.63E-03 1.00E+00 6.14E-03 5.57E-02 32 181 "ZSCAN18,BMP7,FAM19A5,CTH,GREB1,KATNAL2,GSDME,DTNA,HEYL,ST3GAL6,SLC9B2,POLR1B,FGFR1,PRDM5,MKLN1,NPTX1,OXTR,CNTN3,PRTG,ANKRD16,NKAIN1,CCDC40,GAL3ST4,HES6,DHX30,IFT122,CAMTA1,WSCD1,SZT2,ZNF184,INTS3,PCBP4" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_1000_k2 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.63E-03 1.00E+00 6.14E-03 5.57E-02 32 181 "AGT,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,DDR1,CBLN1,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,BAIAP2,FYN,GATM,GPR37,TTYH2,MEF2C,MOV10,MYO7A,SEMA5B,PTPRE,MEG3,ARX,SIN3B,OBSL1,TNS1,NR2C2,TST,SGK3,UBTF" Coexpression Atlas GSM854255_500 "Myeloid Cells, DC.103-11b+.LuLN, MHCII+ CD11c+ CD8- CD11b+ CD103-, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.65E-03 1.00E+00 6.23E-03 5.65E-02 56 366 "FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,ALCAM,SEMA7A,CASK,ZBTB10,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,LY86,SLC4A8,GDA,CSF1R,CST3,CYBB,MYADM,ARRDC4,PLXNC1,RASA4,ENO2,IGSF6,SIRPB1,ZMYND15,RAB30,LOXL3,ADAP1,SLC2A6,INSM1,ITGAM,ASPRV1,PFKFB3,PLCL1,PLTP,PILRA,PID1,ROGDI,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,TMEM150C,ARC,SLC44A1,TRPS1,SPIRE1,PLD4" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k1_500 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.68E-03 1.00E+00 6.32E-03 5.73E-02 10 34 "SEMA6A,LGR5,EDNRB,SEMA3D,LMO2,KITLG,SEPT4,PREX2,KLHL4,TEK" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_500 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.68E-03 1.00E+00 6.32E-03 5.73E-02 27 145 "FMNL2,PPP4R4,SLC16A4,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,EMX2,PACSIN2,KLHL23,MYO9A,SERPINI1,REV3L,HUNK,ST8SIA1,SLC4A3,SNCA,UHRF1BP1L,ST5,ADGRL3,OBSL1,DNAH7,ACTR6,ZNF23" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_100 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.68E-03 1.00E+00 6.32E-03 5.73E-02 16 70 "VAT1L,CADPS,SCRN1,LRRC17,EYA1,TUBB3,IGSF5,STMN2,TAGLN3,NEFM,SLC10A4,MAPK10,EML5,RTN1,SST,UCHL1" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_100 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.69E-03 1.00E+00 6.34E-03 5.75E-02 18 83 "ARHGAP20,LTBP4,BACH1,RUNX1T1,RBM39,EDNRA,GAD1,LPAR4,CHIC1,MEIS2,PCDH9,C1orf54,TMLHE,MEG3,ARX,CBX5,SSBP2,ADAMTS9" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k1_100 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.70E-03 1.00E+00 6.38E-03 5.79E-02 6 14 "TUBB3,STMN2,NEFM,GNG2,SNRPN,PCBP4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200_k5 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.70E-03 1.00E+00 6.38E-03 5.79E-02 6 14 "VAT1L,CACNA2D1,SNCAIP,MEGF10,NEGR1,NEK4" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.70E-03 1.00E+00 6.38E-03 5.79E-02 26 138 "ARHGAP20,AMH,CADPS,CBLN1,VCAN,EDNRA,MRO,PLXNC1,PTK2B,DLC1,AFF2,GATM,FREM1,GUCY1A1,KLHL23,MATN2,PCDH18,RASGEF1B,PTCH1,TMEM255A,ROBO2,ADGRL3,ZFPM2,STOX2,ADAMTS9,WNK3" Coexpression Atlas ratio_MESO_vs_SC_1000_K2 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 1.72E-03 1.00E+00 6.44E-03 5.83E-02 25 131 "C1QTNF1,CFLAR,PLCXD3,GPSM1,DYNC1I1,DTNA,FAM198B,TPPP3,GGT5,PPARGC1A,HP,KIFC3,MITF,MSR1,PALM,PMP22,PTH1R,RNASE1,SH3BGR,CCDC92,SMARCD3,TNS2,ZFPM2,VLDLR,ADAMTS9" Coexpression Atlas gudmap_RNAseq_e15.5_Endothelial_2500 gudmap_RNAseq_e15.5_Endothelial_2500 Gudmap RNAseq 1.73E-03 1.00E+00 6.47E-03 5.87E-02 226 1829 "ABHD6,AS3MT,CCDC85A,ADD2,ADORA2A,MTUS1,HECW2,SORCS2,AK2,ADGRF5,SPARCL1,PITPNM2,SEMA7A,PI16,GAS7,NT5C3B,FAM131A,SHROOM2,ARRB1,MARK4,PTCH2,DYNLL1,ATP1B3,ADAM15,NRP2,GPR146,KSR1,ST3GAL5,ARHGEF7,IL33,LDLRAD4,CA8,THSD7A,HIP1R,LDB2,SCARB1,CD38,ARHGEF2,TBRG4,CHN2,PPT2,FAM189A2,ABCG2,TMEM184B,HOMER3,MYRIP,CNRIP1,CDC42BPB,C2CD2,CREM,AKAP12,CRMP1,ABCG1,AATK,LRRC3B,PLXNA4,PPP1R16B,DOCK4,MYADM,KIF26A,GIT2,ELMO1,C2CD2L,SACS,FAM107B,FIS1,SEZ6L2,EDN1,EDNRB,APH1A,IRAK4,CALCRL,EIF1,TUBD1,RASGRP2,EPHB1,STX2,VPS26C,GMPR2,MRVI1,HSPA12B,REEP2,F8,FAM198B,CORO2B,DLC1,ST3GAL6,CHST15,FCGRT,ATP5PD,PCYOX1,VTI1B,IQCG,FLT1,POMT1,SARAF,FYN,ERAP1,INPP5K,GATM,SESN1,GFER,PCDH17,GGTA1P,LYVE1,FERMT2,GPR12,LPAR4,STMN2,SERP2,GSTT2,IRAK3,ACOT7,HMGCL,ZDHHC15,ICA1,IGF1,IL6ST,IBA57,ITPKB,KIFC3,KIT,LMO2,NCOA7,SMAD1,TM6SF1,MEF2C,MEST,KITLG,MMP17,BLOC1S2,MX1,LYRM9,LAYN,MYO7A,NEXMIF,NOVA2,OGG1,CLDN11,P2RY1,PALM,CDK18,GNG2,SEMA5B,CCSER2,PLEC,SMIM7,PMP22,POLR2F,DRAM2,PPP5C,WBP1L,PSMA6,SNRK,TMEM104,PTK2,PTPRB,CASTOR1,TMEM255A,SH3TC2,C1orf54,SUSD4,RGS3,KCTD17,MRPS18A,ARMC5,RPS6KA2,EMID1,MAPK12,SEMA6D,SCP2,PEAR1,SEC14L1,RASA3,SGK1,FAM102A,SH3GL3,SHMT2,NLGN1,ST8SIA1,WDR37,PREX2,BTBD3,LIMS2,LIMCH1,FAM219A,UNC5B,ARHGAP26,SAMSN1,THSD1,RGL1,STXBP1,PLCB1,ARC,TACC1,MCF2L,TAL1,KLHL4,WSCD1,TCF4,DOCK9,TNS2,CYB561A3,TEK,CHST8,GALNT17,ENHO,HEY1,TLR4,NPL,TUBB2A,FLRT2,MTCH1,WIPF1,CLDND1,NPDC1,AGMO,REEP1,ZNF189,GDPD5,ADAMTS9,TMEM178A,CIAPIN1,NAV3,ITM2C,SPATA13" Coexpression Atlas PCBC_MESO-5_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_1000 PCBC 1.73E-03 1.00E+00 6.47E-03 5.87E-02 130 985 "KCNH8,EMILIN3,GALNT13,PLEKHH1,ADORA1,PTCHD1,C1QTNF1,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,APOC1,LGR5,ARSE,RASL11B,KIF1A,BMP7,BTK,CASTOR3,C5,MYRF,CCK,USP2,L3MBTL4,PLEKHB1,FAM189A2,IGLON5,COL9A1,COL9A3,GAL3ST1,NRG2,RIMS4,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,LONRF1,AIF1L,SV2B,KIF19,SLC25A18,FAM78B,ERBB4,RASL12,ADGRV1,PPP1R1B,MED12L,C2orf88,RASL10A,BRSK1,MEGF10,HRASLS5,GABRB3,GATM,FREM1,GNAL,TMEM121B,FAM222A,HAS2,IGFBPL1,SHISA6,CELF5,NKD1,ZIC5,LRRTM1,C2CD4C,KCNF1,KIT,MATK,MATN3,MYT1,NNAT,NRCAM,IGSF11,PAX6,PCDH8,PRTG,SEMA5B,JAKMIP1,NECAB2,MAGEL2,RASGEF1B,SMIM10L2B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,ACSS3,FAM184A,KHDRBS2,PRIMA1,LGI2,MRAP2,EMID1,SALL1,SEMA6D,TMEM200C,ANKRD6,RCOR3,INAVA,MCF2L2,SSTR2,TMEM150C,KLHL4,FAM189A1,PCDHA6,PCDHA3,PCDHA2,GALNT17,FAM124A,PIK3R5,TRPM2,CA14,RPRM,CLEC2L,VIPR2,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,GAL3ST3,DOCK8,FAM198A,JPH3" Coexpression Atlas PCBC_ratio_SC blastocyst_vs_SC-LF blastocyst_cfr-2X-p05 SC blastocyst_vs_SC-LF blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.73E-03 1.00E+00 6.48E-03 5.87E-02 37 219 "TMEM132B,LDB2,FOXN3,ZNF385A,RIMS4,PNPLA8,TCAF1,DDX46,CHRDL1,KLHL5,PCOLCE2,ARMCX1,NBEA,CAMKK2,MEGF10,IQGAP2,KIT,PFKFB4,SEMA5B,PCDH18,GDPD2,PTN,PRRT2,EXD2,ROBO1,ST6GALNAC6,ASAP3,FHOD3,KDM3A,ZC4H2,RHBDL3,NUDT10,SYT1,TCEAL7,ZNF138,DPYSL5,SRGAP2B" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k2_1000 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.74E-03 1.00E+00 6.49E-03 5.88E-02 35 204 "LGR5,CDC14B,PPP4R4,RGS11,SLC16A4,CDH2,AKAP5,PLXNA4,GPRASP1,DAPK1,DBI,TSPAN5,MTSS1L,AFF2,SHISA6,KLHL23,TTYH2,MATN2,KITLG,AFF1,ETFRF1,SERPINI1,PPP3CC,PRKCB,PTPN13,FRMPD1,ST8SIA1,UHRF1BP1L,TSPYL2,ST5,MTCL1,OBSL1,ZFPM2,TST,WNK3" Coexpression Atlas GSM791126_500 "Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3" "Immgen.org, GSE15907" 1.74E-03 1.00E+00 6.50E-03 5.90E-02 63 423 "FMNL2,ZNF608,OSBPL1A,CDC42BPA,ALDH7A1,MYOM1,MPDZ,BLM,ST3GAL5,PRC1,B4GALT6,SLIT2,ABCG2,MAGED1,ZNF521,CNRIP1,ARHGAP32,EBI3,PLXNC1,CALCRL,MTSS1L,EYA1,ARMCX1,MED12L,NBEA,SMC2,GATM,GCNT2,GRB10,PRDM5,GUCY1A1,IRAK3,HLF,ICA1,LRRCC1,KLHL23,KIT,STMN1,LMO2,MEF2C,MEIS1,MYCN,NME4,OCRL,P2RY1,CNTLN,MEG3,PEAR1,SLC12A2,TET1,THSD1,KLHL4,HIF3A,TEK,CBX5,NPL,STXBP4,SSBP2,TTC3,VIPR2,SPIRE1,PHTF2,NETO2" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k2_1000 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.78E-03 1.00E+00 6.61E-03 5.99E-02 15 64 "SEMA6A,LGR5,CA8,CD38,EDNRB,SEMA3D,LPAR4,JAK2,LMO2,PCDH18,SEPT4,PREX2,KLHL4,TEK,C18orf54" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.78E-03 1.00E+00 6.61E-03 5.99E-02 15 64 "FAM135A,VAT1L,CADPS,RNF182,ADAM23,LDLRAD4,CNR1,EYA1,UBE2E3,GRIA2,MAP4K5,NEGR1,GPR85,TRHDE,ELOVL4" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_200 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.78E-03 1.00E+00 6.61E-03 5.99E-02 15 64 "HECW2,AMH,SEMA7A,ARHGDIG,CADPS,CACNA2D2,ELMO1,DTNA,MRO,CERCAM,ERBB4,FGF13,RASGEF1B,TACC1,SGK3" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_200_k4 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.78E-03 1.00E+00 6.61E-03 5.99E-02 19 90 "CALB1,CRLF1,HAPLN1,CNTNAP2,DUSP9,EMX2,SPSB4,FGF12,RASL10A,MAP7D2,PADI2,FRMD5,VWA2,EML5,RASGRF2,RET,NUDT10,RPRM,VSNL1" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K3 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.78E-03 1.00E+00 6.61E-03 5.99E-02 29 160 "EMILIN3,KIAA1324,ARHGAP20,CDK10,CACNA1G,CDO1,CRLF1,IGDCC3,CSF1R,ELN,LRRC17,FCGRT,TPK1,FYB1,ZNF276,GSN,SYNPO,MBNL1,SRSF12,NFIX,CNTN3,PLCL1,ZMAT4,LIMCH1,ADGRL3,PHF24,TSPAN11,LAMP5,CADM2" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_200_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.78E-03 1.00E+00 6.61E-03 5.99E-02 29 160 "ADORA1,APC,CALB1,RGN,CRLF1,FAM149A,SLC35F1,CRYM,IPCEF1,MFAP3L,EMX2,SPSB4,SMC2,GALC,PPARGC1A,KITLG,PIK3C2A,KANSL1,RASGRF2,RET,REV3L,SCN8A,WSCD1,ERCC6L2,SSBP2,RPRM,UGT8,VLDLR,VSNL1" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.79E-03 1.00E+00 6.62E-03 6.01E-02 32 182 "TMEM108,CA4,CBLN1,CLCN3,FAM169A,HDAC9,CHRDL1,PLEKHA1,PIPOX,REEP2,FGF11,SYT3,GPD2,LPAR4,CDH20,IPO5,AQP11,IGSF11,PRTG,SNX10,PKM,MAGEL2,PTPN13,EMID1,SALL1,SNRPN,PBLD,ADAMTS17,MTCL1,BEX4,ZIC2,SLC38A1" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_500 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.83E-03 1.00E+00 6.78E-03 6.15E-02 11 40 "KLHL13,ARHGAP20,AKAP5,ZNF521,AFF2,NSG1,TCEAL6,KCND2,MAP2,PCDH18,CNTLN" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_100 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_100 FaceBase_RNAseq 1.85E-03 1.00E+00 6.83E-03 6.19E-02 20 97 "GPRASP2,CA4,CDO1,CRLF1,LHX2,IGDCC3,HAPLN1,ELN,GSN,SYNPO,ZIC5,NFIX,NNAT,PRTG,IRX1,ZMAT4,SALL1,ZIC1,ZIC2,SENP7" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.85E-03 1.00E+00 6.83E-03 6.19E-02 20 97 "KDM5D,SEMA7A,GAS7,CADPS,ALDH7A1,DST,ST3GAL5,SCRN1,DTNB,MRO,PLXNC1,PTK2B,GATM,MSI1,RASGEF1B,ROBO1,RPS6KA2,MRAS,SPP1,ADAMTS9" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.85E-03 1.00E+00 6.83E-03 6.19E-02 31 175 "PCDH10,LCORL,INSYN2B,DST,RUNX1T1,DCLK1,CDO1,NCOR1,SPOCK3,DLX1,EYA1,TMEM132C,SCML2,FOXF2,MEGF10,LPAR4,GRIA2,IFI16,MYH3,PCDH8,GPR85,TRHDE,TMEM255A,ZFHX4,ROBO1,CSRNP3,SLC14A1,ADGRL3,PCDHB3,SYNPO2,SOCS4" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_500 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.85E-03 1.00E+00 6.84E-03 6.20E-02 14 58 "ARHGAP20,CBLN1,VCAN,EDNRA,PLXNC1,FREM1,GHR,GUCY1A1,RASGEF1B,LAMA1,ROBO1,ROBO2,MEG3,VSNL1" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_FloorPlate_500 e8.5_NeuroEpith_FloorPlate_top-relative-expression-ranked_500 FaceBase_ST1 1.86E-03 1.00E+00 6.88E-03 6.23E-02 61 408 "LRCH2,CA4,CBLN1,CCNT1,SYNGR3,SOCS6,LHX2,TPP1,FAM19A5,ARMC8,BAG4,CNRIP1,LRRC3B,FAM169A,YTHDC1,FBXL5,PIPOX,REEP2,FOXO3,NOP56,B4GALNT1,GPR162,ZNF638,STMN2,PRDM5,RNF165,KAT7,UBE2QL1,ELOVL5,IGFBPL1,TCEAL6,ICA1,INPP1,KHK,IPO5,PACRG,AQP11,TM6SF1,MIA2,MYCN,NOVA1,PAX6,PMP22,EPDR1,SLC25A36,RPE,ARMH4,ADAL,TRAPPC13,SALL1,PPP4R3A,SNRPN,SPATA7,ELOVL4,ADAMTS17,TBL1X,CCDC173,STXBP4,PPIL6,TBC1D15,PDSS2" Coexpression Atlas GSM399438_500 "B cells, B.FrE.BM, CD19+ IgM+ AA4.1+ HSA+, Bone marrow, avg-3" "Immgen.org, GSE15907" 1.87E-03 1.00E+00 6.91E-03 6.26E-02 57 376 "ZNF608,FGD2,GAS7,ATP6V0A1,BCL7A,BTK,CACNA1I,HIP1R,CD38,LY86,CNN3,AKAP12,PPP1R16B,RUBCN,CYBB,HDAC9,MYADM,ARHGAP24,FBXL5,GUCD1,SLC12A6,EBF1,SNX29,RASGRP1,FRY,KCTD3,SRPK3,EYA1,CHST15,HVCN1,ACSS1,MALT1,IRAK3,BACH2,IRF8,IL12A,LIFR,PIK3AP1,GPR155,MAN2A2,MEF2C,AFF1,NUCB2,PRKCB,RELN,BEND5,ZDHHC14,LRRK2,PPM1E,ST6GAL1,LMBRD1,SYNE2,KIAA0930,CYB561A3,LAT2,SIGLEC10,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_200_k2 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.88E-03 1.00E+00 6.91E-03 6.26E-02 9 29 "ST3GAL6,HP,RETREG1,MBOAT7,PTPRO,DDN,STX1A,TMEM150C,TMEM178A" Coexpression Atlas PCBC_ratio_DE_from-ESC_vs_DE_from-OSKM_cfr-2X-p05 Endoderm Differentiated Cells-reprogram_NA_vs_Endoderm Differentiated Cells-reprogram_OSKM-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.88E-03 1.00E+00 6.91E-03 6.26E-02 9 29 "CALB1,LARGE1,CRMP1,ZNF559,NEFM,RASGEF1B,RET,SPP1,ZNF138" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_500_K5 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.88E-03 1.00E+00 6.91E-03 6.26E-02 9 29 "KLHL32,BMPR1B,CDC25B,SRSF11,LHX2,IGDCC3,EIF5,GSTCD,ZFP2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_200 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.89E-03 1.00E+00 6.97E-03 6.32E-02 12 46 "FAM135A,LDLRAD4,EDIL3,ETV1,FOXF2,MEGF10,RAB40B,IFI16,PCDH8,RGS4,ZFHX4,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_1000_k4 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.90E-03 1.00E+00 6.97E-03 6.32E-02 13 52 "CRYM,ST3GAL6,IQGAP2,FAM107A,SCHIP1,RELN,PTPRO,ROBO2,SALL1,SCN7A,DDN,STX1A,TMEM178A" Coexpression Atlas ratio_SC_vs_MESO_1000_K2 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 1.92E-03 1.00E+00 7.06E-03 6.40E-02 22 111 "ADD2,OLMALINC,DOCK11,CA8,RAB33A,PCYT1B,ARRDC4,RASGRP2,AGAP2,IQGAP2,ACSS1,NEU3,LOXL3,TDRKH,SCIN,KHK,PIK3AP1,PPM1L,BLOC1S2,ALDH1L2,PRKCB,VAV1" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.93E-03 1.00E+00 7.08E-03 6.42E-02 49 313 "NDRG2,PTCHD1,MTUS1,C1QTNF1,APOC1,CACNA1B,CBARP,MYL6B,LETMD1,PPP6R2,MYADM,SPOCK2,HEYL,SEMA3D,EGFR,RPS6KC1,FGF12,PCYOX1,SEMA4D,STAMBP,PCDH17,FAM107A,FRMD3,LRRC75A,ADAM11,MEIS1,MOV10,SAMD14,HS6ST3,NNAT,GPR173,SMOX,FXYD1,TATDN3,PRODH,PTPRG,ATXN7,FERMT1,KIF16B,DOK5,UNC5B,MCF2L,MGRN1,PCDHGA2,SLC44A1,ENHO,TOM1L2,NDRG4,SH3GLB2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k1 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.93E-03 1.00E+00 7.09E-03 6.43E-02 23 118 "EPB41L5,CA8,PPP1R16B,ARHGAP24,FAM107B,EDNRB,ST3GAL6,CGREF1,IGSF5,GUCY1A1,GUCY1B1,TM6SF1,MEF2C,RETREG1,SCHIP1,IRX1,PTPRG,PTPRO,ZDHHC14,SGK1,DDN,NPL,TMEM178A" Coexpression Atlas ratio_DE_vs_SC_1000_K2 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 1.95E-03 1.00E+00 7.16E-03 6.49E-02 75 523 "KCNH8,ACHE,ARHGAP20,PCDH10,TRMT9B,APOC1,LGR5,ARSE,ZBTB10,CASTOR3,C5,BAIAP3,CALB1,THSD7A,CDH2,CRHBP,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,ELMO1,SPOCK3,ERBB4,RASL10A,CAMKK2,GAD1,GATM,FREM1,PCDH17,GNAL,GPR37,GSTT2,FAM222A,HAS2,HNMT,CDH20,KCNF1,KIT,MATN3,LRP1B,RTL5,MYT1,JAKMIP1,PDZRN4,PPP2R2C,RASGEF1B,MAPK10,ELOVL2,RIPOR1,SLC25A48,ACSS3,FAM184A,PRIMA1,ANKRD6,PEG10,MCF2L2,NFASC,SULF2,TMEM150C,RIMBP2,PIK3R5,TRO,TRPM2,TUBB2A,RPRM,PDIA2,VLDLR,KCNK12,PCDH20,ANKS1B,MEIS3,FAM13C,CASC15" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_500 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.97E-03 1.00E+00 7.20E-03 6.53E-02 16 71 "HECW2,APOC1,DST,ST3GAL5,PLXNC1,AFF2,CAMKK2,GPR37,SHISA6,NCOA7,RPS6KA2,MRAS,OBSL1,TST,ADAMTS9,WNK3" Coexpression Atlas GSM538234_500 "Myeloid Cells, DC.103+11b-.Lv, CD45+ CD11c+ MHC-II+ CD11b low CD103+, Liver, avg-2" "Immgen.org, GSE15907" 1.97E-03 1.00E+00 7.22E-03 6.55E-02 61 409 "FMNL2,ADRB2,ADGRF5,ALCAM,AMPD3,FGD2,TMEFF1,ADAM23,ST3GAL5,CD86,LY86,FAM149A,ZNF385A,CDC42BPB,CSF1R,CSF2RA,CST3,CYBB,HDAC9,MYADM,DAPK1,DBN1,ARRDC4,EBI3,PLXNC1,F8,OLFM1,GATM,RAB30,MAP4K5,IRF8,IFI16,LRRC25,JAK2,KIT,LIFR,MYO9A,NUCB2,PDE1B,PRKAB2,RASGEF1B,PTPRB,PID1,C1orf54,ROGDI,SNX22,LRRK2,RTN1,MRAS,SLC8A1,CCDC88A,SLC11A1,TRERF1,SULF2,SEPT3,KIAA0930,TEK,TRPM2,TUBB2A,PLD4,NLRP3" Coexpression Atlas Arv_SC-HD_1000 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000 PCBC 2.01E-03 1.00E+00 7.33E-03 6.65E-02 130 989 "SYN3,TMEM132B,GALNT13,ADD2,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,PLA2G4C,RASL11B,KIF1A,ADGRB1,LDHD,BTK,HAP1,CLDN10,CCK,SYNGR3,ENTPD2,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TOGARAM2,IGDCC3,GDA,LRRC3B,RIMS4,CNTNAP2,SEC14L5,RIPOR2,KCTD8,BRINP1,DPP6,FAM78B,EDNRB,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,IGSF5,GFRA2,GNG4,LPAR4,LINGO1,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,IRF8,C2orf72,ZIC5,KCND2,KCNN1,KIF5A,CAMK2N2,MATK,CHST6,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,SEMA5B,JAKMIP1,SDK2,NECAB2,MAGEL2,EPB41L4B,PPP2R2B,NKAIN4,SMIM10L2B,LAMA1,GDPD2,STK32A,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,HUNK,SALL1,TMEM200C,PPM1E,SLC6A11,SOX3,SOX15,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,RASD2,CA14,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,DPYSL5,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas Arv_SC_fibroblast_1000 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 2.01E-03 1.00E+00 7.33E-03 6.65E-02 130 989 "SYN3,TMEM132B,GALNT13,ADD2,UNC5A,PTCHD1,SEMA6A,SYT13,PDZD4,DOC2A,PLA2G4C,RASL11B,KIF1A,ADGRB1,LDHD,BTK,HAP1,CLDN10,CCK,SYNGR3,ENTPD2,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TOGARAM2,IGDCC3,GDA,LRRC3B,RIMS4,CNTNAP2,SEC14L5,RIPOR2,KCTD8,BRINP1,DPP6,FAM78B,EDNRB,AASS,PIPOX,ADGRV1,PPP1R1B,OLFM1,SYT3,CSPG5,MEGF10,HRASLS5,GABRA3,GABRB3,IGSF5,GFRA2,GNG4,LPAR4,LINGO1,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,IRF8,C2orf72,ZIC5,KCND2,KCNN1,KIF5A,CAMK2N2,MATK,CHST6,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,SEMA5B,JAKMIP1,SDK2,NECAB2,MAGEL2,EPB41L4B,PPP2R2B,NKAIN4,SMIM10L2B,LAMA1,GDPD2,STK32A,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,HUNK,SALL1,TMEM200C,PPM1E,SLC6A11,SOX3,SOX15,SOX21-AS1,SEPT3,ARC,COBL,KLHL4,FAM189A1,CHST8,GALNT17,ENHO,FAM124A,ANKRD24,PIK3R5,RASD2,CA14,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CRB2,DPYSL5,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k5 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.01E-03 1.00E+00 7.33E-03 6.65E-02 8 24 "DCLK1,CDO1,SPOCK3,STMN2,IFI16,NEFM,RTN1,SNAP25" Coexpression Atlas GSM777063_500 "Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4" "Immgen.org, GSE15907" 2.03E-03 1.00E+00 7.40E-03 6.71E-02 66 450 "FMNL2,ADGRF5,SEMA6A,LTBP4,CDC42BPA,SEMA7A,NRP2,IL33,CA8,LDB2,B4GALT6,FAM189A2,CNN3,MAGED1,ZNF521,CDC42BPB,SNCAIP,CSF1,ARHGEF10,PLXNA4,DOCK4,ARMCX4,RCAN1,ARRDC4,ECM2,EDN1,EDNRB,SEMA3D,TMTC1,ELN,CALCRL,F8,ARMCX1,DLC1,FCGRT,ST6GALNAC3,LYVE1,FERMT2,ICA1,LIFR,SMAD1,MEIS2,MSR1,NPR2,CLDN11,ENPP2,PLCD1,PMP22,RELN,PTPRB,RGS4,SH3GL3,BTBD3,UNC5B,RGL1,KLHL4,DOCK9,TNS2,TEK,TIMP4,LRRC8A,NPL,FLRT2,NPDC1,ADAMTS9,MSRB3" Coexpression Atlas gudmap_RNAseq_e15.5_CollectIng Duct_2500_K1 gudmap_RNAseq_e15.5_CollectIng Duct_2500_K1 Gudmap RNAseq 2.04E-03 1.00E+00 7.42E-03 6.73E-02 19 91 "ADCY6,PDE8B,DLGAP1,AATK,CST3,HEYL,ST3GAL6,FGF1,HLF,MMP17,ABCB1,SEPT4,EMID1,PEAR1,SLC8A1,CABCOCO1,UNC5B,GPRIN3,IL34" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_1000 kidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.06E-03 1.00E+00 7.50E-03 6.80E-02 108 801 "ACADM,NDRG2,OSBPL6,ADGRF5,SPARCL1,C6orf89,PKP4,DDO,AQP6,ASPA,ATP1A1,SLC4A4,ALDH7A1,MYOM1,LDHD,CA4,CA12,CALB1,CLDN10,SLC16A4,CDO1,CHRNA4,NDST3,TPP1,CLTB,ABCG2,ARHGEF6,ENTPD4,OSBPL3,CTH,ARHGAP24,DGKB,AIF1L,EBF1,SNX29,EDNRB,FAM13A,AASS,RCAN2,ENPP6,SLC43A2,ERBB4,ETV1,PIPOX,FCGRT,FGF1,FHL1,FOLH1,FUT9,GABRB3,IQGAP2,ACSS1,GATM,IGSF5,ALDH1L1,GHR,PPARGC1A,GPD1,GSTT2,HLF,HNMT,IDH3B,SCIN,KCNJ16,KHK,LAMP2,AQP11,MIA2,MYO6,IGSF11,PDE3A,ENPP2,PGAM2,SERPINI1,MINDY2,PPP1R1A,RANBP3L,PRODH,CNNM2,PTH1R,PTPRB,ACSM5,SUGCT,LRRK2,PTGR2,SCP2,KIF21A,FAM81A,SLC2A5,SLC6A8,SLC8A1,CPEB4,CABCOCO1,SPP1,TEX2,PBLD,NXT2,ADHFE1,SYNE2,PLCB1,TEK,AKTIP,TNS1,NPL,CA14,UGT8,VLDLR,DOCK8" Coexpression Atlas JC_hmvEC_2500_K5 JC_hmvEC_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 2.08E-03 1.00E+00 7.57E-03 6.87E-02 44 275 "C1QTNF1,PI16,DDO,CPNE5,CRLF1,FAM189A2,TRIM69,AATK,PDE4DIP,PLCXD3,TOM1,RASA4,SRPK3,HSPA12B,FLNC,PDLIM5,RASL10A,ABLIM2,GALNT15,LNX1,CCDC184,SERP2,FAM107A,LINC01550,FRMD3,INSYN1,SYNPO,SHISA6,FAM95B1,LRRTM1,KCNN3,CLEC18A,COL28A1,MT1M,NEXMIF,CCDC13,PMP22,NDUFS7,RNASE1,GLDN,LIMS2,PCDHGA2,TNS1,DPF3" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k4 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.10E-03 1.00E+00 7.63E-03 6.92E-02 20 98 "LCORL,ABI3BP,RBM39,DZIP3,CALCRL,EMX2,SCML2,MEX3B,HECTD2,CNOT4,PDPK1,OLA1,TMLHE,FNIP1,SLC12A2,SYNE2,ANKRD12,TSC1,ZNF711,ADAMTS9" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_200 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.10E-03 1.00E+00 7.63E-03 6.92E-02 20 98 "AMPH,CDH2,CNTFR,CRYM,SNCAIP,VCAN,GSDME,SNAP91,ETV1,EYA1,FGFR1,IGSF5,TDRKH,FAM107A,HAS2,NEGR1,CNTN3,SALL1,CUX2,LAMP5" Coexpression Atlas ratio_SC_vs_DE_1000_K4 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 2.11E-03 1.00E+00 7.68E-03 6.96E-02 54 354 "SYN3,UNC5A,VAT1L,CHRNA4,CNTN1,ANKRD35,C1QL2,GALNT9,RIMS4,SEC14L5,JAKMIP2,TMEM130,PARD6A,AASS,PIPOX,OLFM1,HPCAL4,NSG1,IGSF5,TTBK1,TOX3,SOX21,LINGO1,LRRC75A,KCNN2,KCNN3,KIF5A,MMP16,MMP17,MYCN,FXYD7,NELL2,VWA2,NOVA2,NPTX2,NTRK3,NLGN3,PCDH18,EPB41L4B,NKAIN4,GDPD2,TMEM145,TRERF1,LMO3,SOX21-AS1,SEPT3,RHBDL3,ARHGEF9,ARC,SYP,TACR1,VSNL1,TSPAN11,CRB2" Coexpression Atlas GSM605853_100 "Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3" "Immgen.org, GSE15907" 2.12E-03 1.00E+00 7.68E-03 6.97E-02 17 78 "CD86,DGKI,LY86,CSF1R,IGSF6,FCGR3A,GFRA2,HPGDS,IGF1,KCNJ16,MYO9A,P2RY13,PILRA,RASGEF1B,SEMA6D,SLC11A1,TLR4" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_100 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.12E-03 1.00E+00 7.68E-03 6.97E-02 17 78 "LGR5,PPP4R4,PLXNA4,DOCK4,DRP2,EMX2,NRN1,GATM,KLHL23,KITLG,PCDH18,GDPD2,TNFRSF19,SLC4A3,ADAMTS17,ADGRL3,ACTR6" Coexpression Atlas GSM777037_500 "Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4" "Immgen.org, GSE15907" 2.12E-03 1.00E+00 7.70E-03 6.98E-02 67 459 "ADCY5,CCDC85A,TMCC3,C1QTNF1,ADGRF5,SPARCL1,LTBP4,SEMA7A,APBB2,ADAM15,NRP2,CA4,CH25H,LDB2,SCARB1,CD38,ABCG2,CNN3,ZNF521,CDC42BPB,GDA,DOCK4,RCAN1,ARRDC4,ECM2,EBF1,EDN1,EDNRB,CALCRL,HSPA12B,F8,FAM198B,DLC1,ST3GAL6,FLT1,GALNT15,GCNT2,PCDH17,FERMT2,GRB10,ICA1,LIFR,KITLG,AFDN,MYO6,ENPP2,ABCB1,PLTP,PTPRB,PTPRG,C1orf54,FAT4,SEMA6D,SGK1,PREX2,BTBD3,LIMS2,RGL1,PLCB1,KLHL4,DOCK9,TNS2,TEK,TIMP4,TNS1,DCBLD1,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.14E-03 1.00E+00 7.73E-03 7.01E-02 10 35 "CADPS,CALCRL,GFRA2,IGF1,MATN2,CLDN11,LGI2,SATB1,TROVE2,ZFPM2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.14E-03 1.00E+00 7.73E-03 7.01E-02 10 35 "DPP10,CADPS,CACNA1B,GRIN3A,FAM19A2,CLDN11,GPR85,ST8SIA1,CUX2,RPRM" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.14E-03 1.00E+00 7.74E-03 7.02E-02 21 105 "APC,MYOM1,NRP2,CACNA2D1,CPEB2,HIPK3,MRVI1,FHL1,PRUNE2,MBP,PRKCB,RYR3,SCN7A,STUM,SH3BGR,FHOD3,TPM2,SYNPO2,PPIL6,RBFOX3,MSRB3" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.16E-03 1.00E+00 7.80E-03 7.07E-02 24 126 "ARHGAP20,TMEM108,MYRF,CBLN1,CNTFR,VCAN,DNM1,EDNRA,SEMA3D,FLNC,FREM1,CSDC2,GHR,GLI2,GUCY1A1,MEIS1,NME4,PTN,RADX,ROBO2,MEG3,PKNOX2,ASXL3,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.16E-03 1.00E+00 7.81E-03 7.08E-02 22 112 "APOC1,LGR5,CDC14B,CDH2,PLXNC1,FAM198B,AFF2,SEPT9,GATM,GPR37,BVES,SHISA6,SYTL4,MOV10,NEXMIF,PRKCB,ST8SIA1,TSPYL2,OBSL1,BEX4,TST,WNK3" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_500 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.17E-03 1.00E+00 7.85E-03 7.12E-02 64 435 "ADD1,EPB41L5,APLP1,CASK,BACH1,CALM1,CAMK2G,RUNX1T1,ARHGEF2,RBM39,CRMP1,RNF14,CLIP3,CSNK1E,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,GSDME,DNM1L,EPB41L2,TUBB3,SEC24B,FGFR1,MEX3B,DLL3,LPAR4,STMN2,GRB10,BACH2,INSM1,MAPT,NEFM,NNAT,GNG2,PIK3R1,PCDH18,EXOSC10,PRKACB,ZFHX4,MEG3,SUPT20H,ARX,SMARCA4,SNRPN,SOX11,RBM26,SPART,TROVE2,FBXW11,KLHL4,TRIM2,USP22,PUM2,USP1,ZIC1,ZFAND5,INTS3,VPS35L,PCBP4,RTN4" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_500 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.20E-03 1.00E+00 7.94E-03 7.19E-02 14 59 "KLHL13,PPP4R4,PLXNA4,EMX2,AFF2,TRAF3IP2,KLHL23,MATN2,REV3L,ST5,ADGRL3,OBSL1,ZFPM2,WNK3" Coexpression Atlas gudmap_kidney_adult_RenalCapsule_k2_1000 kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.25E-03 1.00E+00 8.11E-03 7.35E-02 56 371 "MTUS1,SRPX,LTBP4,AMPD3,TMEM108,DOCK11,BCHE,RAB29,MYRF,CACNA1A,MS4A7,LY86,ABI3BP,CSF1R,PLXNA4,CYBB,BOC,CHRDL1,CDON,ELN,DENND4A,ABCA8,PTK2B,FCGRT,FYB1,GALNT15,GCNT2,RAB30,LILRB4,GSN,IRAK3,NCKAP1L,IGF1,LAMA2,MATN2,MEIS1,NBL1,NFIX,NPR2,NUCB2,PCDH9,PMP22,NKAIN4,PTPN13,RNASEL,MRAS,CNKSR2,SYNE2,COBL,CYB561A3,ZFPM2,SLC44A1,FLRT2,KCNT2,KCNAB1,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_100_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.27E-03 1.00E+00 8.17E-03 7.41E-02 11 41 "PCDH10,SPOCK3,TMEM132C,FOXF2,MEGF10,GRIA2,IFI16,MYH3,TRHDE,ZFHX4,CSRNP3" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k4_200 kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.28E-03 1.00E+00 8.20E-03 7.43E-02 13 53 "AMPH,CACNA2D1,CACNB4,CNTFR,CRYM,SNCAIP,SNAP91,ETV1,EYA1,HAS2,NEGR1,MEIS2,TPM2" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000_k4 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.30E-03 1.00E+00 8.26E-03 7.49E-02 30 170 "LCORL,LGR5,PDE8B,INSYN2B,SYNJ1,ARHGEF7,SCAPER,GREB1,DTNB,DNAJB6,SCML2,AIFM3,MAP7D2,KCND2,KITLG,MYO5A,NEXMIF,PDPK1,ABCB1,SERPINI1,JAKMIP1,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,LARP4,ANKRD12,DMXL2,DOCK9" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4 Gudmap RNAseq 2.32E-03 1.00E+00 8.34E-03 7.56E-02 36 215 "C1QTNF1,PDE8B,MYOM1,CALB1,DLGAP1,ARHGEF6,DGKB,ZNF804A,EBF1,EMX2,LRRC17,EPHB1,TLR7,FCGRT,TPPP3,LOXL3,GUCY1A1,IL6ST,MITF,NTRK2,PDE3A,PIK3R1,PLCL1,FXYD1,PTN,FAM184A,PREX2,SLC8A1,NKAIN2,RGL1,TNS2,GALNT17,TLR4,PLSCR4,FAM13C,MSRB3" Coexpression Atlas gudmap_kidney_adult_GlomCapSys_Tie2_k2_1000 kidney_adult_GlomCapSys_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.32E-03 1.00E+00 8.34E-03 7.56E-02 19 92 "TAOK1,ARRB1,CFLAR,THSD7A,CLOCK,MYADM,CEP85L,CORO2B,ST3GAL6,FERMT2,MAPT,CCSER2,RIPOR1,ZDHHC14,FAM81A,CPEB4,LMBRD1,TNS2,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_500_k4 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.38E-03 1.00E+00 8.52E-03 7.73E-02 29 163 "RALGAPA1,TAOK1,OGT,APC,EPB41L5,CFL2,COL4A5,PLPPR4,SEMA3D,MED12L,SUCO,SYNCRIP,PDLIM5,SYT17,PPARGC1A,KIF2A,CHIC1,KITLG,PIK3C2A,KANSL1,REV3L,TRA2B,SLC8A1,FAM126B,MYCBP2,VPS13A,ERCC6L2,RGMB,SSBP2" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_1000 DevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.41E-03 1.00E+00 8.64E-03 7.84E-02 110 822 "ABCF1,ADD1,AGT,TBC1D14,AK2,ABCD2,LTBP4,AMH,OGT,SEMA7A,EPB41L5,ARHGDIG,ARRB2,BACH1,ST3GAL5,PRMT9,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,SCARB1,PLAA,SULT4A1,COL9A3,RBM39,RNF14,CLIP3,FAM169A,PUM1,ARHGAP32,DAPK3,DBI,DBN1,DCTN1,GSDME,RCAN1,DTNA,DNM1L,EDNRA,PLXNC1,EPB41L2,NRN1,PTK2B,SCML2,FGFR1,BAIAP2,IQCG,FYN,GATM,MAP7D2,GPR37,GRB10,GUCY1A1,GUCY1B1,TTYH2,MAPT,MBP,MEF2C,MOV10,MYO7A,NEXMIF,NFYA,NNAT,PCDH8,SEMA5B,PCDH18,PLTP,EXOSC10,PRKACB,BCAS3,PTPRE,ROBO2,MEG3,ATXN2,PUF60,ARX,SHMT2,WDR37,RADIL,SMARCA4,SNRPN,RBM26,SPART,JMJD6,PJA1,FBXW11,SIN3B,OBSL1,PUM2,TMPO,TNS1,TPM1,NR2C2,TST,SGK3,UBTF,UCHL1,USP1,ZNF142,ZFAND5,INTS3,STOX2,ADAMTS9,CIAPIN1,VPS35L,PCBP4,RTN4" Coexpression Atlas PCBC_ratio_SC_vs_MESO-15_cfr-2X-p05 Pluripotent Stem Cells_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.41E-03 1.00E+00 8.65E-03 7.84E-02 241 1976 "ABCF1,TMEM132B,ADD2,AXIN2,PWWP2A,MTA3,OSBPL1A,WDR35,SEMA6A,FAM135A,VAT1L,TMEFF1,ATP1A3,ATP1B3,KIF1A,ADAM15,BLM,NAE1,MTMR2,GPC2,CACNA2D1,PTBP2,CBR1,CBS,CLDN10,LDB2,DCLK1,LRWD1,TBRG4,UBE2L6,CACNA2D2,FOXN3,CHN1,PLAA,PCYT1B,COL9A1,COL9A3,TBPL1,NECTIN3,CRMP1,LRIG1,SOCS5,RIMS4,FAM169A,PHF14,USP6NL,FAM131B,KIF26A,LONRF1,MATR3,DAPK1,BRINP1,AIF1L,DBN1,PITPNC1,ARMCX2,JAKMIP2,DDX46,ALKBH8,SACS,CHRDL1,NR1D2,DPYSL2,DNAJB6,FARSB,FCF1,AASS,PCOLCE2,EPB41,ERBB2,ERCC2,PIPOX,CD320,REEP2,NSRP1,TBC1D16,TUBA1B,TUBB3,PRMT5,PPP1R1B,ZNF589,OLFM1,POLR1B,FGF13,FGFR1,MAD2L2,FHL1,SYNCRIP,SEMA4D,FLT1,NOP56,NBEA,SMC2,CELF1,NSG1,MEGF10,GABRB3,MTHFD2,GCNT2,RNPS1,DBF4,GLI2,TNRC6A,CBX1,KDM2B,GNG4,GRIK5,ZNF496,CIT,KAT7,SOX21,LINGO1,PSIP1,ACOT7,IGFBPL1,CPT1C,DHX35,ICA1,ZIC5,RBPJ,LRRCC1,KLHL23,KCNN2,KIF2A,KIF5A,IPO5,L1CAM,STMN1,MSANTD3-TMEFF1,CHST6,MMP17,MPP2,THYN1,MYCN,BEX5,HNRNPM,NEFM,NELL2,NPTX2,OPA1,PDCD2,FAM98B,SEMA5B,NLE1,FAM216A,PCDH18,MAPKAP1,PSAT1,EPB41L4B,FSD1,PPM1B,PPP2R2B,PPP5C,PRKAR1B,GDPD2,PTN,ZIK1,PTPRG,NKAIN1,RBBP8,UBR7,NUDT11,ZNF532,ROBO1,MCMBP,TUNAR,CCDC112,RMI1,SALL1,HES6,CASC3,TRA2B,SH3GL3,SHMT2,SLC6A8,SEPHS1,CCDC88A,ATF7IP,TET1,COA1,OGDHL,SNRPN,TRERF1,SOX11,SP4,ZNF423,DBNDD2,SEPT3,STXBP1,KLHL7,ZC3H4,RHBDL3,ARHGEF9,NUDT10,SYT1,ANKRD28,MTCL1,AGTPBP1,FBXW11,KLHL4,ATMIN,TCEA1,WSCD1,TCF4,TRIM2,SIRT1,GALNT17,ENHO,RELL2,TMPO,FAM124A,R3HDM1,KAT6B,PDSS1,TSN,CA14,HSPBP1,TUBB2A,UCHL1,USP1,CCDC136,VSNL1,CLIP2,WRN,XPO1,CFAP298,ZIC2,ZNF74,TCEAL7,ZNF195,SMARCAD1,DHX33,SLC38A1,TUBA1A,GAL3ST3,MRPL47,HNRNPA3,ACTR3B,JMJD1C,LAS1L,JPH3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_500 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.42E-03 1.00E+00 8.67E-03 7.86E-02 23 120 "CDC42BPA,NUMB,SLC16A4,DCLK1,DRP2,TMEM35A,MTSS1L,PACSIN2,AFF1,MYO9A,NELL2,NUCB2,SERPINI1,PIK3C2A,PTPRG,WDR37,SNCA,UHRF1BP1L,DOCK9,DNAH7,PCDH20,SIGLEC10,DPF3" Coexpression Atlas gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_k3_500 kidney single cell_e11.5_MetanephMesench_StemCellamp_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.42E-03 1.00E+00 8.67E-03 7.86E-02 23 120 "MTUS1,IQCK,COL9A1,MYEF2,FGF13,SMC2,KCNMB4,ZDHHC15,KIAA1755,MEIS2,SAMD14,NTRK2,FSD1,PTN,TSPY26P,SH3GL3,DZIP1,CXXC4,SOX11,ENHO,FAM155A,MEIS3,NETO2" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500_k2 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.44E-03 1.00E+00 8.72E-03 7.90E-02 9 30 "FAM169A,DOCK4,GSDME,MEX3B,ZKSCAN3,RBM26,KLHL4,ACTR6,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_100 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.44E-03 1.00E+00 8.73E-03 7.92E-02 17 79 "CD38,CNTN1,COL9A1,ST3GAL6,FYB1,IGSF5,NEGR1,TM6SF1,MSR1,CLDN11,OXTR,PTPRO,PTX3,SALL1,DDN,TLR4,SYNPO2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.45E-03 1.00E+00 8.74E-03 7.92E-02 28 156 "KDM5D,GAS7,CADPS,RGN,CDH2,SCRN1,POM121,CPEB2,DTNB,MRO,PLXNC1,FAM198B,PTK2B,CAMKK2,PPARGC1A,ADGRA3,GPR37,RASGEF1B,PRKCB,PTCH1,ROBO1,GLDN,MRAS,ST6GAL1,BEX4,ADAMTS9,WNK3,FZD3" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_1000 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.45E-03 1.00E+00 8.75E-03 7.94E-02 15 66 "MTUS1,TXNDC16,ALCAM,ADAM23,BCHE,IL33,BOC,SPOCK2,ARRDC4,EXTL2,MMP16,NFIX,EPDR1,SULF2,TPM2" Coexpression Atlas GSM605827_500 "Myeloid Cells, DC.8+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 2.51E-03 1.00E+00 8.94E-03 8.11E-02 59 397 "FMNL2,RNF150,ADRB2,ADGRF5,ALCAM,FGD2,TMEFF1,N4BP2L1,ADAM23,ST3GAL5,BTK,CD86,CD38,CHN2,LY86,FAM149A,CST3,CYBB,ARRDC4,PLXNC1,PLEKHA1,IGSF6,OLFM1,FLT1,TMEM107,GALC,GATM,RAB30,GPR34,MAP4K5,IRF8,LRRC25,KIT,LIFR,ADAM22,MYO9A,NUCB2,PDE1B,PFKFB3,PRKAB2,RASGEF1B,PID1,C1orf54,ROGDI,SNX22,LRRK2,RTN1,SLC8A1,CCDC88A,SLC11A1,SLC12A2,FNBP1,SULF2,SEPT3,ADGRL3,CYB561A3,TRPM2,TUBB2A,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.52E-03 1.00E+00 8.97E-03 8.13E-02 27 149 "EMILIN3,USP31,APC,BMP7,CACNA2D1,KALRN,CLIP3,VCAN,ELMO1,GRIN3A,DNM1,EDNRB,HIPK3,IQGAP2,SYT17,PCDH17,KIAA1958,GRIA2,BACH2,MKLN1,PDE3A,KANSL1,REV3L,ZHX3,ERCC6L2,RGMB,TRPS1" Coexpression Atlas GSM538225_500 "B cells, B1a.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23- CD21/35-, Spleen, avg-3" "Immgen.org, GSE15907" 2.54E-03 1.00E+00 9.04E-03 8.19E-02 52 341 "ABHD6,TXNDC16,ALCAM,SEMA7A,FGD2,ATP6V0A1,BTK,CACNA1I,HIP1R,CD86,CD38,CDC25B,LY86,AKAP5,RUBCN,CYBB,HDAC9,MYADM,RIPOR2,ARHGAP24,SLC12A6,EBF1,EBI3,PLXNC1,SRPK3,TLR7,HVCN1,AK8,RAB30,BACH2,MEF2C,AFF1,MYO5A,NUCB2,PPP3CC,RASGEF1B,PRKCB,DIRAS2,MARCH1,BEND5,LRRK2,LMBRD1,SLC37A2,TCF4,DMXL2,CYB561A3,TLR4,C9orf85,LAT2,SIGLEC10,PLD4,PHTF2" Coexpression Atlas ratio_MESO_vs_SC_1000_K5 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.54E-03 1.00E+00 9.04E-03 8.20E-02 70 487 "KCNH8,ADORA1,PCDH10,TRMT9B,APOC1,LGR5,ARHGDIG,ARSE,BMP7,ST3GAL5,CASTOR3,C5,MYRF,CFAP410,CDH2,CNR1,COL4A5,NRG2,CNTNAP2,PLXNA4,PYGO1,ARHGAP24,SV2B,SPOCK3,ERBB4,RASL12,AMOTL2,RASL10A,DENND2A,GATM,FREM1,PCDH17,GPR37,TMEM121B,FAM222A,HAS2,LRRTM1,CDH20,KCNF1,LIFR,MATN3,MYT1,SETD4,OXTR,CNTN3,PAX6,PCDH8,ENPP2,PDZRN4,MAPK10,LAMA1,ELOVL2,FAM184A,ST8SIA1,ANKRD6,SLC9A5,MCF2L2,NFASC,SSTR2,SSPO,TMEM150C,PHF24,FAM189A1,PIK3R5,TRO,TRPM2,TTC3,RPRM,KCNK12,ANKS1B" Coexpression Atlas gudmap_developingKidney_e15.5_500_k3 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.54E-03 1.00E+00 9.04E-03 8.20E-02 34 201 "RALGAPA1,ABHD6,BEND6,APC,EPB41L5,TNRC6C,SLC4A4,CACNA2D1,CLCN3,NCOR1,GOLT1B,MED12L,SYNCRIP,SMC2,PPARGC1A,KIF2A,CHIC1,MKLN1,CNOT4,KANSL1,RASGRF1,REV3L,ZFP2,FAM126B,ZHX3,MYCBP2,PRRC2C,MGRN1,ERCC6L2,RGMB,SSBP2,VLDLR,ADAMTS9,DOCK8" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.56E-03 1.00E+00 9.08E-03 8.23E-02 18 86 "USP31,PCDH10,DPP10,NRP2,CACNA1B,CRHBP,VCAN,PLCXD3,GRIN3A,GFRA2,PCDH17,IFI16,NDP,CLDN11,PRPH,REV3L,ZFHX4,CUX2" Coexpression Atlas GSM399442_100 "Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2" "Immgen.org, GSE15907" 2.56E-03 1.00E+00 9.08E-03 8.23E-02 18 86 "GDA,ARHGAP32,PLXNC1,MED12L,GCNT2,TUBA8,GRB10,GUCY1A1,HLF,ICA1,KIT,LMO2,MEIS1,MYCN,OCRL,SLC14A1,TEK,STXBP4" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k5 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.56E-03 1.00E+00 9.08E-03 8.23E-02 18 86 "EMILIN3,CACNA2D1,CHN2,CNTN1,COL9A1,NCALD,MRVI1,MEGF10,GFRA2,RAB40B,NEGR1,CLDN11,PTX3,LGI2,SH3BGR,PLCB1,SYNPO2,FLRT2" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_100 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.56E-03 1.00E+00 9.08E-03 8.23E-02 18 86 "BACH1,RUNX1T1,RBM39,EDNRA,EIF4G1,LPAR4,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,TMLHE,MEG3,ARX,CBX5,SSBP2,FLRT2,ADAMTS9" Coexpression Atlas GSM777046_500 "Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4" "Immgen.org, GSE15907" 2.57E-03 1.00E+00 9.09E-03 8.24E-02 64 438 "GALNT16,SPARCL1,SRPX,ARHGAP20,LTBP4,PI16,SGCE,SLIT2,MAGED1,ABI3BP,ZNF521,CLIP3,CSF1,VCAN,BOC,DAPK1,SPOCK2,CHRDL1,DNM1,CDON,ECM2,EBF1,EDNRA,EGFR,PCOLCE2,ELN,LRRC17,FAM198B,DLC1,FCGRT,FGFR1,FHL1,SCARA3,TPPP3,GALNT15,GHR,FERMT2,GRB10,GSN,GSTM5,HAS2,IGF1,LAMA2,MATN2,MEIS1,MEIS2,NBL1,NFIX,NOVA1,NPR2,ENPP2,CYTL1,PCDH18,PLTP,PMP22,PTX3,KIRREL1,SCN7A,TNS2,TEK,SLC44A1,TNS1,FLRT2,AGMO" Coexpression Atlas Arv_SC-hpx_blastocyst_1000_K3 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 2.58E-03 1.00E+00 9.12E-03 8.27E-02 73 512 "SYN3,TMEM132B,ADCY8,SEMA6A,PDZD4,RASL11B,KIF1A,HAP1,CLDN10,DLGAP1,FAM189A2,FAM19A5,SULT4A1,IGLON5,COL9A1,COL9A3,GAL3ST1,C1QL2,RIMS4,CNTNAP2,FAM169A,SEC14L5,KCTD8,BRINP1,DPP6,AASS,PIPOX,ADGRV1,PPP1R1B,SYT3,CSPG5,MEGF10,HRASLS5,GABRB3,GNG4,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ZIC5,KCND2,KIF5A,CAMK2N2,FXYD7,PSAT1,NECAB2,PPP2R2B,LAMA1,GDPD2,TMEM145,NKAIN1,RET,SALL1,TMEM200C,SOX3,HECW1,SEPT3,ARC,COBL,KLHL4,ENHO,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,KCNT2,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_200 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.60E-03 1.00E+00 9.20E-03 8.34E-02 14 60 "FMNL2,DOCK4,DAPK1,KLHL5,EMX2,NRN1,KLHL23,KITLG,MYO9A,TNFRSF19,RASA3,SLC4A3,KDM3A,ACTR6" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k2_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.61E-03 1.00E+00 9.21E-03 8.35E-02 29 164 "HECW2,APBB2,ABCG1,LRRC3B,PITPNC1,SEZ6L2,RASGRP2,EPHB1,CORO2B,FLT1,TRIM16,PCDH17,HP,LMO2,MEF2C,MEIS2,NCF2,PDE4B,SCHIP1,SNRK,RIPOR1,SH3TC2,RGS3,ARHGAP26,TNS2,NPL,NPDC1,GDPD5,RGS7BP" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k4_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.61E-03 1.00E+00 9.21E-03 8.35E-02 29 164 "ADD1,AK2,DDR1,CBLN1,ARHGEF1,PUM1,ARHGAP32,DBI,DCTN1,RCAN1,EDNRA,MBNL2,EPB41L2,STAMBP,KIF2A,SMAD1,MEF2C,MEG3,ARX,PJA1,TMPO,TNS1,TST,UBTF,UCHL1,USP1,ZFAND5,VPS35L,ADAMTS10" Coexpression Atlas GSM538262_500 "Myeloid Cells, DC.8-4-11b+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-1" "Immgen.org, GSE15907" 2.63E-03 1.00E+00 9.26E-03 8.39E-02 61 414 "FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,CASK,ZBTB10,N4BP2L1,ATP6V0A1,MYOM1,ADAM23,NRP2,CFLAR,LARGE1,UBE2L6,B4GALT6,ARHGAP22,LY86,SLC4A8,CSF1R,OSBPL3,CST3,CYBB,MYADM,RASSF2,GUCD1,ARRDC4,PLXNC1,RASA4,IGSF6,SIRPB1,ZMYND15,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,HSF2,JAK2,KIT,ASPRV1,PFKFB3,ROGDI,RGS12,LRRK2,RTN1,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,TMEM150C,ARC,SLC44A1,TRPS1,ZBTB38,SPIRE1,SIGLEC10,PLD4" Coexpression Atlas GSM854271_500 "Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2" "Immgen.org, GSE15907" 2.63E-03 1.00E+00 9.26E-03 8.39E-02 61 414 "FMNL2,TMCC3,PTCHD1,ALCAM,FGD2,GAS7,ADAM23,NRP2,DST,CD86,MS4A7,B4GALT6,ARHGAP22,LY86,GDA,CSF1R,CSF2RA,CST3,CYBB,DOCK4,MYADM,DAPK1,RCAN1,RASA4,DENND4A,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,ZMYND15,TPPP3,GATM,HPGDS,IGF1,LRRC25,ITGAM,LIFR,MITF,MSR1,MYO5A,P2RY13,NCF2,NFE2L2,PLTP,PMP22,PILRA,RASGEF1B,PID1,CCDC88A,SLC11A1,ITPRID2,RGL1,SULF2,TLR4,TNS1,TRPS1,LAT2,AGMO,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K3 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 2.63E-03 1.00E+00 9.28E-03 8.41E-02 25 135 "KDM5D,CDK10,CRLF1,PCYT1B,CDON,DUSP9,ETV1,TMEM132C,ST6GALNAC3,ZNF276,SYNPO,IGF1,LAMA2,MBNL1,SRSF12,PCSK5,PDE3A,ZFHX4,PREX2,LIMCH1,TAF9,ASXL3,AMACR,TRPS1,CA14" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.64E-03 1.00E+00 9.29E-03 8.42E-02 35 209 "LGR5,CDC14B,PPP4R4,PDE8B,RGS11,SLC16A4,CDH2,AKAP5,GPRASP1,DBI,DBT,AFF2,ZMAT1,RAB30,SHISA6,KLHL23,KITLG,AFF1,NEXMIF,ETFRF1,SEMA5B,PPP3CC,PRKCB,PTPRD,MEG3,ST8SIA1,UHRF1BP1L,ARHGAP26,TSPYL2,ST5,MTCL1,OBSL1,ZFPM2,TST,WNK3" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000_k3 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.64E-03 1.00E+00 9.29E-03 8.42E-02 19 93 "RBM39,GSDME,SNAP91,DNAJB6,PLXNC1,GATM,GGT5,MAP7D2,SHISA6,SYTL4,NEXMIF,ABCB1,SATB1,CPEB3,SLC12A2,SYNE2,ANKRD12,CAMTA1,DMXL2" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 2.64E-03 1.00E+00 9.29E-03 8.42E-02 19 93 "APOC2,ZFYVE28,PDE8B,ATP1A3,BARD1,ZNF599,IL33,KCNAB3,VAX2,CRYBB1,PTK2B,ZMYND15,ABLIM2,SCIN,GPR155,PDE4D,STRC,DUSP15,DNAH10" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_200 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.65E-03 1.00E+00 9.31E-03 8.44E-02 31 179 "C1QTNF1,EPB41L5,UPRT,TMEM108,CA12,THSD7A,DOCK4,ARHGAP24,AIF1L,TMTC1,OPTN,TLR7,ACSL4,ST3GAL6,ST6GALNAC3,GALC,IQGAP2,MALT1,PARD3B,SYNPO,MYO6,PTH1R,PTPRO,RIPOR1,ROBO2,FAM81A,CPEB4,KANK1,TMEM150C,FRYL,PLEKHH2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_100 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_100 FaceBase_ST1 2.66E-03 1.00E+00 9.31E-03 8.44E-02 16 73 "PCDH19,TAOK1,LHX2,RAB33A,CNTNAP2,SCRN1,JAKMIP2,EFCAB2,UBE2QL1,LYRM9,PAX6,MINDY2,HSPA4L,KIF21A,NR2E1,XRCC4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.66E-03 1.00E+00 9.31E-03 8.44E-02 16 73 "NDRG2,SPARCL1,ADGRB1,CST3,RASSF2,DBI,LYPD1,EDNRB,ETV1,PCDH17,LUZP2,NTRK2,SCHIP1,PTN,S100B,ZEB1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k2 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.66E-03 1.00E+00 9.31E-03 8.44E-02 16 73 "CFL2,CNTN1,MFAP3L,CPEB2,TMTC1,NRN1,PRKAG2,CGREF1,IL6ST,NFIX,PPP3CA,CLIP1,RYR3,SYNPO2,UCHL1,FAM13C" Coexpression Atlas ratio_SC_vs_DE_500_K5 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 2.68E-03 1.00E+00 9.39E-03 8.51E-02 42 263 "SYN3,UNC5A,VAT1L,CHRNA4,ANKRD35,C1QL2,RIMS4,SEC14L5,RIPOR2,JAKMIP2,PARD6A,AASS,PIPOX,OLFM1,HPCAL4,IGSF5,TTBK1,SOX21,LINGO1,LRRC75A,KCNN2,KCNN3,KIF5A,FXYD7,VWA2,NPTX2,NTRK3,NLGN3,PCDH18,EPB41L4B,GDPD2,TMEM145,TRERF1,SOX21-AS1,SEPT3,RHBDL3,ARHGEF9,ARC,SYP,TACR1,VSNL1,TSPAN11" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500_k3 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.69E-03 1.00E+00 9.41E-03 8.53E-02 8 25 "AMPH,CRYM,SNAP91,EYA1,TVP23A,HAS2,PRTG,MAPK12" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500_k4 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.72E-03 1.00E+00 9.50E-03 8.61E-02 21 107 "ADCY5,MYOM1,NRP2,DMPK,CPEB2,DTNA,FHL1,IGSF5,TPPP,IFI16,PRKCB,STUM,SH3BGR,FHOD3,TNS1,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 2.72E-03 1.00E+00 9.50E-03 8.61E-02 13 54 "CBLN1,LHX2,SLITRK5,PIPOX,REEP2,GABRB3,TOX3,STMN2,SHISAL1,NRCAM,SALL1,MAPK12,SNRPN" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_500_k4 DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.72E-03 1.00E+00 9.50E-03 8.61E-02 13 54 "USP31,DPP10,CACNA1B,HAPLN1,BRINP1,GRIN3A,EDIL3,FGF13,SYT17,PPARGC1A,SAMD5,MAGEL2,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.72E-03 1.00E+00 9.50E-03 8.61E-02 13 54 "PCDH10,RUNX1T1,DCLK1,CRLF1,SCRN1,DLX1,TMEM132C,FOXF2,MEGF10,GRIA2,ZFHX4,LIMCH1,SOX11" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K5 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.72E-03 1.00E+00 9.50E-03 8.61E-02 22 114 "NDRG2,PTCHD1,C1QTNF1,CSF1,MYADM,SPOCK2,HEYL,SEMA3D,EGFR,GSN,FAM107A,FRMD3,INPP1,MEIS1,MEIS2,NNAT,SMOX,PRODH,BAALC,FERMT1,MCF2L,NDRG4" Coexpression Atlas PCBC_DE_500 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 2.78E-03 1.00E+00 9.70E-03 8.79E-02 71 497 "KCNH8,SEMA6A,PCDH10,UNC79,PDZD4,APOC1,LGR5,ARSE,RASL11B,KIF1A,CALB1,CLDN10,FAM189A2,IGLON5,COL9A1,GAL3ST1,IPCEF1,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,BRINP1,PIPOX,ADGRV1,MEGF10,HRASLS5,CHL1,GABRB3,GAD1,GATM,FREM1,GNAL,TMEM121B,HAS2,IGFBPL1,KCND2,KIT,MATN3,SEMA5B,JAKMIP1,PDZRN4,PPP2R2B,PPP2R2C,LAMA1,ELOVL2,SLC25A48,FAM184A,RET,PRIMA1,HUNK,TMEM200C,SOX3,MCF2L2,NUDT10,TMEM150C,KLHL4,FAM189A1,GALNT17,ENHO,PIK3R5,TRPM2,CA14,RPRM,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k4_200 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.79E-03 1.00E+00 9.72E-03 8.81E-02 7 20 "CRMP1,TUBB3,STMN2,INSM1,NEFM,ZIC1,PCBP4" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_100_k4 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.79E-03 1.00E+00 9.72E-03 8.81E-02 12 48 "CALB1,CRLF1,CNTNAP2,EMX2,SPSB4,RASL10A,FRMD5,VWA2,RASGRF2,RET,RPRM,VSNL1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.79E-03 1.00E+00 9.72E-03 8.81E-02 12 48 "APOC1,LGR5,PLXNC1,FAM198B,AFF2,GPR37,SHISA6,MOV10,ST8SIA1,ST5,OBSL1,WNK3" Coexpression Atlas gudmap_RNAseq_e15.5_CollectIng Duct_2500 gudmap_RNAseq_e15.5_CollectIng Duct_2500 Gudmap RNAseq 2.85E-03 1.00E+00 9.90E-03 8.97E-02 218 1776 "SYN3,AS3MT,ADCY6,PLEKHH1,ADORA1,ADORA2A,AK2,ADGRF5,DOC2A,AMPD3,AMT,FGD2,LCORL,MYH7B,EPB41L5,APOC1,CPNE5,LGR5,PDE8B,ATP1A1,BID,PROM1,BMP7,BMPR1B,IL33,CA4,CA8,CALB1,HAP1,CD38,LRBA,DLGAP1,CRLF1,CACNA2D2,CBARP,B4GALT6,CNOT8,SLIT2,PPT2,MYL6B,FAM189A2,QKI,FAM149A,COL9A3,ABCG1,CRYM,AATK,LRRC3B,OSBPL3,IPCEF1,CST3,CTH,GREB1,TMEM170A,SPOCK2,DBI,AIF1L,MFAP3L,DUSP9,FIS1,SEZ6L2,EDNRB,HEYL,SEMA3D,EEF1D,IRAK4,TMEM35A,EMX2,COQ7,ERBB4,CD320,SH3YL1,ACSL4,ST3GAL6,FGF1,SPSB4,FGF12,PCYOX1,VTI1B,SEMA4D,FLT1,C2orf88,POMT1,PDLIM5,TPK1,RASL10A,CAMKK2,ERAP1,SYT17,IGSF5,GFER,MMADHC,PPARGC1A,DHRS4,TOX3,KDM2B,LNX1,GPR12,SERP2,GSTT2,FAM222A,PADI2,FRMD5,INSYN1,HLF,ACOT7,SHISAL1,INPP1,ITPKB,SLC35G1,KCNJ16,KIT,L1CAM,STMN1,LMO2,LYPLAL1,AQP11,MBP,ADAM11,KITLG,MMP17,DBNL,COMMD5,BLOC1S2,MYO6,NEXMIF,VWA2,NPY,NOVA2,NRCAM,KSR2,OGG1,PALM,CDK18,PDE4A,PDE1B,ABCB1,RETREG1,KCTD15,SMIM7,PLXNB1,PSAT1,SEPT4,POLR2F,PPP1R1A,MAPK4,GDPD1,PSMA6,LAMA1,TMEM255A,SLC25A48,SUSD4,ROGDI,RASGRF2,RET,MRPS18A,NUDT11,GLDN,EMID1,SALL1,SCN8A,SCP2,HES6,PEAR1,FAM102A,SH3GL3,FERMT1,SHMT2,FHOD3,ST6GAL1,FAM81A,SLC8A1,LIMCH1,CABCOCO1,KDM4B,SOX11,UNC5B,SPTB,THSD1,STAC2,STX1A,KANK1,TMEM150C,ARC,SYT5,TAL1,KLHL4,WSCD1,CUX2,GPRIN3,TEK,CHST8,TMEM9,HEY1,BEX4,IL34,DCBLD1,CA14,RPRM,UCHL1,CCDC136,VLDLR,VSNL1,CFAP298,ATP6V0E2,DPYSL5,SLC38A1,GDPD5,ADAMTS9,TMEM178A,CIAPIN1,SEMA3B,ITM2C,PCBP4,WNK2,DOCK8,TTC7A,SPATA13" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_HindBrain_500 e8.5_NeuroEpith_HindBrain_top-relative-expression-ranked_500 FaceBase_ST1 2.86E-03 1.00E+00 9.92E-03 9.00E-02 64 440 "ACADM,NDRG3,FZD9,VAT1L,ATP2A2,PRMT9,CA4,CBLN1,CLDN10,CCNT1,SOCS6,SULT4A1,CNTFR,BAG4,SCRN1,IP6K1,JAKMIP2,FBXL5,EXOG,TSPAN5,PLEKHA1,C8orf37,PIPOX,VPS26C,REEP2,ST3GAL6,POLR1B,PRELID3A,CELF1,ZNF638,RNF165,KAT7,SOX21,UBE2QL1,ELOVL5,ZDHHC15,ICA1,NKD1,IPO5,AQP11,POC1B,ELOVL2,CASTOR1,RAD17,DPF2,SLC25A36,RIC8B,MCMBP,SCP2,TNFRSF19,SUPT20H,PPP4R3A,PKNOX2,SPATA7,SPART,LHPP,TAF6,TBL1X,WSCD1,MTMR14,CLEC2L,CLDND1,PDSS2,ACTR3B" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K5 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.86E-03 1.00E+00 9.92E-03 9.00E-02 35 210 "ADCY8,ALCAM,CA4,FOXN3,HAPLN1,CSF1,LRRC3B,HDAC9,FGF11,FGFR1,SYT3,CSDC2,LINGO1,GUCY1A1,HMGCL,TCEAL6,CDH20,GATD1,KHK,MATN2,PRTG,ZFYVE21,PLEC,PMP22,IRX1,NKAIN4,PTPRE,TSPY26P,C12orf49,KIAA0895L,EMID1,SALL1,SLC4A3,ADAMTS17,ZIC2" Coexpression Atlas Lungmap Mouse Lung E16.5 Epithelial Subtype Noncycling AT1 Precursor Lungmap Mouse Lung E16.5 Epithelial Subtype Noncycling AT1 Precursor Lungmap CCHMC 2.89E-03 1.00E+00 1.00E-02 9.07E-02 63 432 "ZNF608,KIAA1324,PKP4,PDE8B,RASL11B,RGS11,NAE1,DDR1,CLDN10,DCLK1,CLCN3,COL4A5,NCOR1,PITPNM3,KIAA0040,DOCK4,RASSF2,DAPK1,EDN3,ANKRD46,FAM13A,ING4,RASL12,FGF1,FGFR3,FHL1,TRIM16,KIAA1841,IGSF5,TUBA8,GFRA2,GSTT2,SYNPO,LYPLAL1,DBNL,MXI1,NNAT,CHAMP1,GPR85,FXYD1,PMP22,PPP2R2B,RASGEF1B,PTPN13,PTPRD,CASTOR1,SLC25A36,HES6,ZFP2,SHMT2,CNKSR2,PEX26,SLC6A8,TTC17,SYPL1,TBL1X,TCF4,TRIM2,PUM2,AKTIP,TNS1,METTL3,LYPD6" Coexpression Atlas GSM854309_500 "Myeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 2.93E-03 1.00E+00 1.02E-02 9.22E-02 61 416 "FMNL2,ADRB2,ZNF608,MTUS1,ALCAM,ABCD2,AMPD3,SUGT1P4-STRA6LP-CCDC180,CASK,NUMB,ATP1A3,ATP6V0A1,BACH1,ST3GAL5,GDA,CSF1,CSF1R,CSF2RA,CYBB,MYADM,FBXL5,ARRDC4,OPTN,EBI3,IGSF6,SIRPB1,ST3GAL6,FCGR3A,GCNT2,GGT5,GSN,SLC2A6,IRAK3,HNMT,HP,LRRC25,IL6R,ITGAM,LAMP2,SFXN5,ASPRV1,MITF,P2RY13,NCF2,NFE2L2,NNAT,PFKFB4,SMOX,PILRA,RPS6KA2,SEC14L1,SLC11A1,ABTB1,TMCC1,SPP1,SAMSN1,DMXL2,SLC44A1,TLR4,TRPM2,NLRP3" Coexpression Atlas PCBC_ratio_PulmonMicrovasc_vs_SC_2X-p05 Pulmonary Microvascular_vs_Pluripotent Stem Cells-fold2.0_adjp0.05 PCBC_AltAnalyze 2.94E-03 1.00E+00 1.02E-02 9.23E-02 224 1831 "MTUS1,HECW2,ADGRF5,SPOP,ALCAM,SRPX,PITPNM2,CDC42BPA,C6orf89,SMIM29,ARHGDIA,ARRB1,MARCH3,NUMB,INSYN2B,ADAM15,BCS1L,NRP2,BID,CFLAR,SYNJ2,AP1M1,CAST,HIP1R,PRC1,LDB2,ARHGEF1,CDC25B,LRRFIP1,CCPG1,CFL2,TAOK2,STOML1,CLTB,HOMER3,ABI3BP,ZNF521,CNRIP1,AKAP12,RNF14,ABCG1,OSBPL3,CST3,PPP1R16B,KIAA0040,GPSM1,DOCK4,ARHGAP24,RASSF2,GIT2,ELMSAN1,ELMO1,RUSC2,FAM107B,CD99L2,PDCD6IP,TSPAN5,EDN1,PHC2,HIPK3,KLHL5,FRY,OPTN,MBNL2,IRAK4,CERCAM,MRNIP,CALCRL,SLC43A2,DENND4A,SIRPB1,HSPA12B,NRN1,FAM198B,TAOK3,DLC1,CHST15,FCGRT,SLC9B2,BAIAP2,AMOTL2,PRKAG2,SCARA3,FLNC,FLYWCH1,PDLIM5,TPK1,ST6GALNAC3,AP4B1,GHDC,ERAP1,INPP5K,TUBA8,GGT5,LYVE1,DHRS4,MSL3,SLC2A6,TOX2,ZHX1,TNFAIP8L3,SYNPO,C9orf129,IDH3A,IFI16,MYLK2,IL6ST,INPP1,ITPKB,KIFC3,STXBP5,LAMP2,LIFR,LIMS1,LMO2,SYTL4,NCOA7,SMAD1,SMAD9,MAN2A2,MBNL1,TM6SF1,MEF2C,DBNL,NRBP2,LAYN,MYO5A,NBL1,NFE2L2,NFIX,NRCAM,NUCB2,TBC1D25,CLDN11,PALM,PDE4B,CYTL1,ZDHHC8,PLEC,PMP22,SH3KBP1,PPP3CC,PRKACB,MAPK3,RELN,VPS13C,SNRK,PTPRB,PTPRE,PTX3,RIPOR1,FAT4,RAP1GDS1,ZDHHC14,RGS3,RGS4,RNH1,ARMC5,RPS6KA2,STK32B,CLIP1,MAPK12,PEAR1,SEC14L1,GALNT10,RASA3,SGK1,WDR37,ABLIM3,LIMS2,WDR47,FAM214B,SIRT2,SLC12A2,ANKRD36,SNCA,CMTR2,TEX2,ARHGAP26,CAMTA2,ITPRID2,THSD1,MPRIP,RGL1,DIP2A,SULF2,TACC1,DNMBP,TAL1,PDLIM2,NR2F1-AS1,ZEB1,SZT2,DOCK9,TNS2,SLC35G2,CYB561A3,TEK,RP9P,ZMAT3,NACC2,HEY1,TLR4,TRIO,DCBLD1,UBC,OSBP2,FLRT2,PLPPR2,TOM1L2,NPDC1,NDRG4,ZBTB38,SPIRE1,SLC30A3,RNF103,ADAMTS9,PLSCR4,MSRB3,NHSL1,SNX14,FRMD6,NETO2,SRGAP2B" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K2 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.98E-03 1.00E+00 1.03E-02 9.33E-02 24 129 "AMPD2,IGDCC4,GPC2,PCYT1B,CLIP3,ACOT8,BAIAP2,NBEA,HIGD1B,RAB30,HLF,SMAD9,SAMD5,N6AMT1,NPY,PDE4D,PFKFB2,DIRAS2,CNKSR2,ARHGAP26,ARHGEF9,PHF24,HIF3A,STXBP4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.00E-03 1.00E+00 1.04E-02 9.40E-02 19 94 "AXIN2,LGR5,NSG1,TCEAL6,IGF1,KCND2,LAYN,NEXMIF,NPR2,ENPP2,GDPD2,FAT4,RNASEL,SEMA6D,TNFRSF19,ADAMTS17,TCF12,DCBLD1,LYPD6" Coexpression Atlas GSM777041_500 "Stromal Cells, Ep.MEChi.Th, CD45- EpCAm+ Ly51- MHCIIhi, Thymus, avg-2" "Immgen.org, GSE15907" 3.01E-03 1.00E+00 1.04E-02 9.43E-02 57 384 "ACHE,FMNL2,SLC24A4,KIAA1324,ALCAM,DPP10,GAS7,CADPS,ATP6V0A1,ADAM23,SYNJ2,CACNA1B,MAGI1,CDO1,CNN3,CRHBP,GDA,SPOCK3,DMPK,SNX29,RGS17,NBEA,GATM,IGSF5,HAS2,HNF4G,IGF1,KNDC1,SCIN,INSM1,TTYH2,ASPRV1,MEIS2,MSI1,MYO6,PDE1C,CCSER2,GDPD1,PTPN13,SH3TC2,ROBO1,HUNK,KIF21A,FERMT1,CCDC88A,SPP1,SST,SSPO,ST5,SYT1,DOCK9,SIRT1,RASD2,SYNPO2,TRIO,ADAMTS9,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000 dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.05E-03 1.00E+00 1.05E-02 9.52E-02 22 115 "HFM1,CPNE5,NAE1,SCAPER,LONRF2,DZIP3,FBXL5,DUSP9,SCML2,EFCAB2,MAP7D2,ADAM22,ZCWPW1,HSPA4L,SH3BGR,CNKSR2,ZNF667,GKAP1,VPS13A,DMXL2,RUNDC3B,UGT8" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.05E-03 1.00E+00 1.05E-02 9.52E-02 22 115 "KALRN,CDH2,COL9A1,SIPA1L1,PYGO1,SPOCK2,SNAP91,RAB39B,KMT5B,PRELID3A,TVP23A,KIAA1958,FAM19A2,HAS2,MSI1,CEP41,RPS6KA2,MAPK12,DZIP1,ANKRD6,CEP68,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_500_k2 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.05E-03 1.00E+00 1.05E-02 9.52E-02 22 115 "MYOM1,NRP2,DMPK,CPEB2,DTNA,IGSF5,PRUNE2,BVES,IL6ST,NPTX2,PRKCB,RYR3,STUM,SH3BGR,LIMS2,DBNDD2,TNS1,TPM1,TPM2,SYNPO2,RBFOX3,RGS7BP" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.05E-03 1.00E+00 1.05E-02 9.52E-02 22 115 "SEMA7A,CDC14B,BCHE,RGS11,DST,RGN,CDH2,GPRASP1,MRO,PLXNC1,CERCAM,AFF2,ZMAT1,GATM,ADGRA3,TTYH2,SYTL4,MOV10,RASGEF1B,TSPYL2,TST,WNK3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgla_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgla_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 3.05E-03 1.00E+00 1.05E-02 9.53E-02 53 352 "CALB1,PRC1,CDH2,CDO1,CDR1,COL4A5,ZNF521,CNRIP1,CNTNAP2,MYEF2,SEZ6L2,EXTL2,ABCA8,TMEM132C,NBEA,TMEM107,ERGIC3,NTNG2,GRM8,FAM107A,KCND2,LAMP2,LRP1B,MID1,AFDN,NUCB2,CNTN3,PAX6,PKM,PCDH18,PLTP,FAT4,RFX3,GALNT10,STUM,SH3BP2,ARX,SEPHS1,ZNF334,PEG10,RBM26,ZNF621,SULF2,SYNE2,TCF12,HEY1,ZIC1,ZIC2,ATP6V0E2,DNALI1,FAM13C,NHSL1,SPATA13" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k5 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.06E-03 1.00E+00 1.05E-02 9.55E-02 14 61 "PCDH19,EPB41L5,HEYL,ST3GAL6,RASL10A,IGSF5,HP,OXTR,PTPRO,FAM184A,DUSP15,DDN,TMEM150C,HEY1" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k3_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.06E-03 1.00E+00 1.05E-02 9.55E-02 14 61 "CDC14B,NRN1,AFF2,TRAF3IP2,KLHL23,MATN2,MEIS1,PCDH18,REV3L,ST5,ADGRL3,OBSL1,ZFPM2,TRPS1" Coexpression Atlas PCBC_ctl_geo-heart_500 geo_heart_top-relative-expression-ranked_500 PCBC 3.08E-03 1.00E+00 1.06E-02 9.59E-02 71 499 "ADCY5,AGT,C1QTNF1,ADGRF5,SPARCL1,PI16,MYH7B,DDO,CPNE5,PLA2G4C,ATP1A3,MYOM1,AZGP1,GPR146,LDHD,CAMK2A,CAMK2B,USP2,TOGARAM2,CSF1R,PDE4DIP,PLCXD3,DGKG,SRPK3,RCAN2,F5,ABCA8,FCGR3A,FGF12,FOLR2,ABLIM2,IP6K3,HIGD1B,ALDH1L1,TUBA8,CSDC2,GGTA1P,PPARGC1A,LYVE1,GPD1,PLPP7,FAM107A,UBE2QL1,HBA1,FRMD3,INSYN1,HLF,VSIG4,HP,IGF1,ITGA7,KCNK3,PGAM2,DUSP26,RETREG1,PLCL1,PLIN1,FXYD1,PPP1R1A,RNASE1,SCN7A,ABLIM3,SLC4A3,LIMS2,SLC8A1,SLC11A1,FAIM2,SPTB,VIPR2,LGI4,SLC30A3" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k5 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.10E-03 1.00E+00 1.06E-02 9.64E-02 38 234 "NDRG2,ADCY8,SRPX,ARHGAP20,PTCH2,ADGRB3,JAZF1,IL33,LDB2,DCLK1,CRYBB1,PLCXD3,RIPOR2,MFAP3L,CHRDL1,EDNRA,ENO2,ETV1,FCGRT,FGF1,FUT9,GAD1,TNRC6A,GLUL,HTATSF1,PARD3B,MATN2,NTRK3,PCSK5,NALCN,PTN,C1orf54,LGI2,MRAP2,PCDHB9,RASD2,VLDLR,RGS7BP" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K3 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 3.12E-03 1.00E+00 1.07E-02 9.70E-02 70 491 "ACADM,AS3MT,ESYT2,PTCHD1,MPDZ,BLM,CARS,CCNH,AP4M1,LRBA,ARHGEF2,CNOT8,TAOK2,COL9A1,SH2B1,HAPLN1,DBN1,KIAA0753,DLX1,DTNB,DNAJB6,HEYL,SEMA3D,ASB3,RABEPK,EYA1,GMPR2,TBC1D16,VTI1B,DCTN2,NFU1,MSL3,STON1,GSN,GSTM5,KAT7,MBD1,MEIS2,DBNL,MYCN,NFYA,ZDHHC8,KANSL1,PRODH,WBP1L,C1orf109,KIF7,ALG9,RPS6KA2,ST6GALNAC6,COPZ1,FERMT1,BTBD3,MPRIP,MMS19,TAF9,SIN3B,USP22,ACTR6,BHLHB9,CABIN1,METTL3,TSN,SLC35A4,BCL2L13,CLIP2,CLDND1,ZNF189,ZFAND5,NAV3" Coexpression Atlas GSM538315_500 "NK cells, NK.Sp, NK1.1+, Spleen, avg-3" "Immgen.org, GSE15907" 3.13E-03 1.00E+00 1.07E-02 9.71E-02 60 409 "AS3MT,RNF157,ADORA2A,KCNAB2,GAS7,CDC14B,ATP1B3,BAIAP3,CAMK2G,CHN2,ABCG2,OSBPL3,RIPOR2,PITPNC1,TIAM2,DOCK2,PDCD6IP,FAM78B,TNK2,DENND4A,RASL12,EYA1,ST3GAL6,FER,OLFM1,FYN,B4GALNT1,MALT1,GP1BB,PADI2,IRF8,ITGAM,KIT,PIK3AP1,TM6SF1,MYO6,ABCB1,PIK3R1,PPP3CC,OXR1,KCNIP3,SATB1,PEAR1,RASA3,FAM102A,ELMO2,SMARCD3,ARHGAP26,ST5,SULF2,KLHL4,GPRIN3,FRYL,PIK3R5,TRIO,RUNDC3B,LAT2,PLSCR4,MARCH8,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_100_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.13E-03 1.00E+00 1.07E-02 9.71E-02 9 31 "CACNB4,RBM39,CRYM,DYNC1I1,EYA1,FGF1,FAM19A2,FAM107A,FRMD3" Coexpression Atlas GSM538285_500 "NK cells, NK.49CI+.Sp, NK1.1+ CD3- Ly49C/I+, Spleen, avg-3" "Immgen.org, GSE15907" 3.19E-03 1.00E+00 1.09E-02 9.90E-02 57 385 "AS3MT,ADORA2A,KCNAB2,GAS7,CDC14B,BAIAP3,CD38,CHN2,ABCG2,OSBPL3,RIPOR2,DOCK2,FAM78B,TSPAN5,TNK2,DENND4A,NCALD,RASL12,EYA1,ST3GAL6,FER,OLFM1,FYN,GP1BB,PADI2,ZDHHC15,IRF8,ITGAM,KIT,TM6SF1,MYO6,ABCB1,PIK3R1,PPP3CC,PRKACB,FAM184A,OXR1,ATP8B4,KCNIP3,SATB1,PEAR1,ELMO2,SMARCD3,ARHGAP26,ST5,SULF2,KLHL4,GPRIN3,FRYL,CDH22,TLR4,TRIO,RUNDC3B,LAT2,PLSCR4,MARCH8,SPATA13" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_100 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 3.23E-03 1.00E+00 1.10E-02 1.00E-01 17 81 "LGR5,PPP4R4,CALB1,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,FREM1,GUCY1A1,KCND2,KLHL23,PCDH18,TMEM255A,ADGRL3,VSNL1" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.23E-03 1.00E+00 1.10E-02 1.00E-01 25 137 "LGR5,CALB1,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,LRRC17,NRN1,AFF2,GATM,FREM1,GUCY1A1,KCND2,KLHL23,MATN2,MEIS1,KITLG,PCDH18,KDM3A,ADGRL3,ZFPM2,ACTR6,LYPD6" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500_K3 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 3.23E-03 1.00E+00 1.10E-02 1.00E-01 25 137 "CCDC85A,ARHGAP20,CDK10,ADGRB2,ZNF599,LRBA,CDO1,CRLF1,IGDCC3,CSF1R,DUSP9,ELN,LRRC17,FCGRT,FYB1,ZNF276,SYNPO,MITF,NFIX,CNTN3,PLCL1,ZMAT4,ADGRL3,PHF24,TSPAN11" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_200 DevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.25E-03 1.00E+00 1.11E-02 1.01E-01 28 159 "USP31,ADGRF5,CA8,CD86,CD38,LY86,RBM39,CSF1R,CYBB,ELMO1,FCGR1A,FLT1,FYB1,PCDH17,LYVE1,NCKAP1L,MSR1,PTPRB,TMEM255A,SGK1,SLA,PREX2,SAMSN1,THSD1,KLHL4,ARHGAP9,TEK,TLR4" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K1 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 3.30E-03 1.00E+00 1.13E-02 1.02E-01 24 130 "TBC1D14,APOC2,ARRB2,ZNF599,SUMF2,CRY2,ELN,NCALD,CDKL3,HPCAL4,FYB1,GSN,GPR155,MID1,ETFRF1,PILRA,CYBC1,STRC,REV3L,KCNIP3,RXRA,PEX26,PDLIM2,LAMP5" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k4_200 dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.33E-03 1.00E+00 1.14E-02 1.03E-01 18 88 "ADGRF5,SPARCL1,LDB2,EBF1,RASGRP2,FLT1,PDLIM5,PCDH17,LPAR4,LMO2,TM6SF1,MEF2C,PTPRB,TMEM255A,PREX2,LIMCH1,THSD1,TEK" Coexpression Atlas ratio_EB_vs_SC_1000_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 3.34E-03 1.00E+00 1.14E-02 1.03E-01 15 68 "AGT,SPARCL1,CAMK2A,AKAP6,FLNC,UBE2QL1,IGF1,MAPT,PDE1C,PLCL1,PTH1R,TNS1,SYNPO2,TOM1L2,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.35E-03 1.00E+00 1.14E-02 1.03E-01 10 37 "PCDH10,DCLK1,TMEM132C,FOXF2,MEGF10,IFI16,MYH3,ZFHX4,SALL1,CSRNP3" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.36E-03 1.00E+00 1.14E-02 1.04E-01 23 123 "LGR5,RGN,SLC16A4,CDO1,QKI,VCAN,MTSS1L,FAM198B,CAMKK2,PPARGC1A,GPR37,MATN2,PPP3CC,PRKCB,REV3L,RNASE1,ST6GAL1,ST8SIA1,OBSL1,ZFPM2,TST,SLC38A1,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k1 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.40E-03 1.00E+00 1.16E-02 1.05E-01 39 243 "SPARCL1,SRPX,ATP2A2,NRP2,CAMK2G,LRRFIP1,PDE4DIP,DMPK,CPEB2,ELN,RASGRP2,FHL1,FLNC,KHDRBS3,IGSF5,PRUNE2,MCHR1,TPPP,IL6ST,MBNL1,NRBP2,ALDH1L2,NPTX2,FXYD1,PILRA,PRKAB2,PSD,LIMS2,FNBP1,DBNDD2,KANK1,COBL,ENHO,TNS1,RASD2,TPM1,TPM2,SYNPO2,RGS7BP" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.41E-03 1.00E+00 1.16E-02 1.05E-01 11 43 "ADAM23,CHRDL1,PCOLCE2,PDE4B,RYR3,SLC14A1,SYN2,TIMP4,SYNPO2,AGMO,FAM13C" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_500 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.42E-03 1.00E+00 1.16E-02 1.05E-01 46 298 "ADORA2A,HECW2,ADGRF5,MAP4K3,APBB2,SHROOM2,NRP2,ARHGEF7,CD38,ABCG2,CRMP1,RASSF2,GIT2,ELMO1,EBF1,EDNRB,CALCRL,RASGRP2,CORO2B,DLC1,FLT1,PDLIM5,FYB1,PCDH17,GGTA1P,LPAR4,GRIA2,MAP4K5,ICA1,LMO2,TM6SF1,MEF2C,SNRK,PTPRB,TMEM255A,C1orf54,PREX2,LIMCH1,UNC5B,THSD1,KLHL4,TEK,HEY1,WIPF1,NAV3,FAM13C" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_200 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.43E-03 1.00E+00 1.16E-02 1.05E-01 29 167 "ADORA1,EPB41L5,BMP7,THSD7A,TMCC2,OPTN,SRPK3,EPHB1,CGREF1,GALC,IQGAP2,IGSF5,PARD3B,HP,MAPT,RETREG1,SCHIP1,MBOAT7,KANSL1,PTPRO,RIPOR1,DUSP15,REV3L,SALL1,MYCBP2,DDN,STX1A,TMEM150C,TMEM178A" Coexpression Atlas PCBC_MESO-5_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 3.45E-03 1.00E+00 1.17E-02 1.06E-01 70 493 "KCNH8,ADORA1,UNC79,PDZD4,APOC1,LGR5,ARSE,KIF1A,BMP7,BTK,C5,MYRF,CCK,USP2,IGLON5,COL9A1,COL9A3,GAL3ST1,NRG2,CNTNAP2,PPP1R16B,PLCXD3,SV2B,FAM78B,ERBB4,RASL12,ADGRV1,MEGF10,HRASLS5,GABRB3,GATM,FREM1,GNAL,TMEM121B,FAM222A,HAS2,IGFBPL1,HP,KCNF1,KIT,MATN3,MYT1,IGSF11,SEMA5B,JAKMIP1,MAGEL2,RELN,LAMA1,ELOVL2,STK32A,SLC25A48,FAM184A,KHDRBS2,PRIMA1,SALL1,TMEM200C,MCF2L2,SSTR2,TMEM150C,FAM189A1,GALNT17,PIK3R5,TRPM2,CA14,RPRM,KCNK12,ANKS1B,CADM2,GAL3ST3,JPH3" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K1 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 3.47E-03 1.00E+00 1.17E-02 1.07E-01 26 145 "TMEM108,CA4,CBLN1,CLCN3,FAM169A,CHRDL1,PLEKHA1,PIPOX,REEP2,GPD2,LPAR4,CDH20,IPO5,IGSF11,PRTG,SNX10,PKM,MAGEL2,GDPD2,PTPN13,SALL1,SNRPN,PBLD,MTCL1,BEX4,ZIC2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.54E-03 1.00E+00 1.20E-02 1.09E-01 8 26 "PCDH10,EYA1,TMEM132C,FOXF2,IFI16,MYH3,ZFHX4,CSRNP3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.57E-03 1.00E+00 1.21E-02 1.09E-01 25 138 "KDM5D,AMH,SEMA7A,MAGED1,CD99L2,MRO,PLXNC1,ERBB4,FAM198B,PTK2B,TUBB3,FGF13,IQGAP2,GATM,PPARGC1A,ADGRA3,STON1,RASGEF1B,MASP1,TSPYL2,SYNE2,THRA,CLDND1,ADAMTS9,WNK3" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 3.65E-03 1.00E+00 1.24E-02 1.12E-01 39 244 "EMILIN3,ARHGAP20,CDK10,ADGRB2,CACNA1G,LDLRAD4,CACNA2D1,KCNAB3,CDO1,CRLF1,ANKRD44,CRYM,CSF1R,DUSP9,ELN,LRRC17,FCGRT,TRIM16,DLL3,FYB1,TMEM8B,ZNF276,SYNPO,KLHL23,SRSF12,TCEAL5,CNTN3,PLCL1,ACSS3,ZMAT4,ZFHX4,DGLUCY,ADGRL3,PHF24,FAM189A1,TRPS1,TSPAN11,LAMP5,CADM2" Coexpression Atlas gudmap_developingGonad_e18.5_testes_500 DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.68E-03 1.00E+00 1.24E-02 1.13E-01 60 412 "TMCC3,ADD1,AGT,SORCS2,C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,BACH1,ST3GAL5,DDR1,CALM1,CBLN1,SCARB1,RBM39,RNF14,PUM1,ARHGAP32,DAPK3,SPOCK2,DBI,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,FGFR1,GATM,GPR37,GRB10,IL6ST,MEF2C,MYO7A,NEXMIF,NFIX,NNAT,SEMA5B,PCDH18,PTPRE,MEG3,ARX,SPP1,SULF2,OBSL1,PUM2,TNS1,TST,UCHL1,USP1,ZFAND5,PCBP4,RTN4" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_200 kidney_P0_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.73E-03 1.00E+00 1.26E-02 1.14E-01 23 124 "ALCAM,AMPH,IL33,CACNA2D1,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,ETV1,EYA1,FGFR1,IGSF5,FREM1,HAS2,NEGR1,MEIS2,CNTN3,ROBO2,SALL1,CUX2,TPM2" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k2_1000 dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.74E-03 1.00E+00 1.26E-02 1.15E-01 31 183 "SUGT1P4-STRA6LP-CCDC180,MARK4,ATP1B3,NRP2,ARHGEF7,CD38,ABCG2,TMEM184B,LY86,CRMP1,HAPLN1,FAM107B,EDNRB,CALCRL,DENND4A,UFM1,PDLIM5,FYB1,HPGDS,GLUL,STMN2,NCKAP1L,ICA1,MAPK3,SGK1,SAMSN1,KLHL4,TEK,C18orf54,TLR4,RNF146" Coexpression Atlas gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_1000 kidney single cell_e11.5_MetanephMesench_StemCellamp_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.81E-03 1.00E+00 1.29E-02 1.17E-01 88 646 "KIAA1211,MTUS1,CDC14B,TMEFF1,ARHGDIG,CCAR2,ATP1A3,DOCK11,BARD1,CABP7,ARHGEF25,HOMER3,CNTFR,IQCK,COL9A1,COL9A3,ZNF521,CSNK1E,VCAN,KIAA0408,MYADM,ARMCX4,MYEF2,DUSP9,EBF1,MRO,DCTN4,USPL1,CDKL3,FGF13,FOXO3,EVL,SMC2,CAMKK2,BRSK1,SEPT9,KCNMB4,SERP2,ZBTB45,PSIP1,ZDHHC15,HSPA1L,KIAA1755,KIF5A,STMN1,MEIS1,MEIS2,MEST,SAMD14,MYCN,LINC00672,MYO9A,NNAT,NTRK2,TMOD2,ZDHHC8,NLE1,NECAB2,SH3KBP1,FSD1,PTN,C1orf54,TSPY26P,FIGN,MEG3,SH3GL3,DZIP1,CXXC4,SOX11,ZNF423,ARHGEF9,MCF2L,SIN3B,CUX2,C18orf54,GALNT17,ENHO,TPM2,FAM155A,TMEM198,MEIS3,EMSY,SLC38A1,ADAMTS9,PCBP4,HNRNPA3,NETO2,GAN" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k3 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.85E-03 1.00E+00 1.30E-02 1.18E-01 20 103 "USP31,APBB2,RIPK1,KSR1,CD38,PPP1R16B,CALCRL,EPHB1,DLC1,FLT1,PCDH17,LMO2,NCF2,RELN,RGS3,MAPK12,PREX2,TLR4,GDPD5,MSRB3" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.02E-03 1.00E+00 1.35E-02 1.23E-01 12 50 "PCDH19,GSDME,MEX3B,ROBO2,ZKSCAN3,RBM26,RGL1,KLHL4,CLASP1,ASXL3,TPM1,WNT7A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k5 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.02E-03 1.00E+00 1.35E-02 1.23E-01 12 50 "TRMT9B,MAGI1,FAM171B,HAPLN1,EDIL3,CHL1,GABRB3,STMN2,MAGEL2,RGS4,PCDHB7,STOX2" Coexpression Atlas GSM854262_500 "Myeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7" "Immgen.org, GSE15907" 4.02E-03 1.00E+00 1.35E-02 1.23E-01 56 381 "FMNL2,FGD2,ADAM23,CD86,CD38,RCBTB2,MS4A7,B4GALT6,FAM189A2,LY86,GDA,CSF1R,CSF2RA,CYBB,DOCK4,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,ZMYND15,TMEM107,MPP6,GATM,HPGDS,LOXL3,IFI16,LRRC25,ITGAM,TTYH2,LIFR,MITF,MSR1,P2RY13,NCF2,NUCB2,PDE1B,PLTP,PILRA,RASGEF1B,GDPD1,RNASEL,RTN1,SEMA6D,SLC8A1,SLC11A1,RGL1,SULF2,SLC37A2,ADGRL3,DMXL2,NPL,TRPM2,AGMO,PLD4,NLRP3" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k1_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.02E-03 1.00E+00 1.35E-02 1.23E-01 41 261 "ABCF1,KDM5D,ADD1,SEMA7A,GAS7,ARHGDIG,CBLN1,QKI,COL9A3,RBM39,PPP1R16B,PLCXD3,PUM1,RIPOR2,MATR3,DTNA,PHF20L1,PLXNC1,PTK2B,FYN,MTHFD2,CSDC2,ZNF638,GPR37,MEF2C,PLTP,SH3KBP1,PPP2R5E,PTPRE,MEG3,ARX,WDR37,PKNOX2,SMARCA4,ADHFE1,TACC1,OBSL1,TNS1,NR2C2,UBTF,STOX2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.07E-03 1.00E+00 1.36E-02 1.24E-01 16 76 "ALCAM,ARHGAP20,CBLN1,VCAN,EDNRA,PLXNC1,GFRA2,FREM1,PPARGC1A,GUCY1A1,PCDH18,TMEM255A,ROBO2,ADGRL3,VSNL1,STOX2" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.07E-03 1.00E+00 1.36E-02 1.24E-01 16 76 "LGR5,CDC14B,PPP4R4,RGS11,AFF2,SHISA6,KLHL23,KITLG,NEXMIF,UHRF1BP1L,TSPYL2,ST5,OBSL1,ZFPM2,TST,WNK3" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_1000 kidney_e13.5_Podocyte_MafB_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.07E-03 1.00E+00 1.36E-02 1.24E-01 89 656 "KLHL32,ARHGAP20,MARCH4,MAGEE2,SEC11C,CA8,CACNA2D1,C1orf52,ZNF521,CRYM,AATK,SNCAIP,CSF1,VCAN,CENPL,GSDME,SRPK3,CALCRL,EYA1,AFF2,EFCAB2,UFM1,FYB1,IGSF5,FREM1,LYVE1,AP4S1,HAS2,UBE2QL1,ARHGAP36,HP,NEGR1,IBA57,INSM1,LIG4,TM6SF1,MGAT3,AFF1,LYRM9,NCF2,NEFM,NPY,NOVA1,PDCD2,OLA1,SPDL1,PTN,PTPRB,PTX3,FAM184A,RBBP6,DUSP15,TSPY26P,RMI1,SALL1,LRFN5,CNKSR2,SLC4A3,GKAP1,CMTR2,ERC1,SST,NUDT10,ADAMTS17,TAF9,KLHL4,NEU4,CUX2,PCDHB9,PCDHB7,PCDHB3,TEK,DNAH7,ITGB3BP,BHLHB9,TLR4,TNS1,TPM2,CHST5,STXBP4,TRPS1,RPRM,FLRT2,ZNF708,KCNT2,STOX2,MRPL47,SMIM8,NETO2" Coexpression Atlas geo_heart_500_K3 geo_heart_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 4.07E-03 1.00E+00 1.36E-02 1.24E-01 31 184 "ADCY5,AGT,C1QTNF1,CPNE5,ATP1A3,LDHD,CAMK2A,CSF1R,PDE4DIP,RCAN2,FCGR3A,FOLR2,IP6K3,CSDC2,GPD1,UBE2QL1,INSYN1,HLF,VSIG4,ITGA7,DUSP26,PLCL1,PLIN1,FXYD1,RNASE1,SCN7A,SLC4A3,LIMS2,SLC8A1,FAIM2,VIPR2" Coexpression Atlas GSM399376_500 "alpha beta T cells, T.4SP69+.Th, 4+ 8- TCRhi 69+, Thymus, avg-3" "Immgen.org, GSE15907" 4.08E-03 1.00E+00 1.37E-02 1.24E-01 54 365 "ACTN1,NDRG2,ADCY6,ARHGAP20,PITPNM2,SFMBT2,GPR146,ARHGEF1,CNN3,LRIG1,SIPA1L1,PPP1R16B,CDON,RASGRP1,TMEM35A,TLR7,TMEM164,MEX3B,FYN,CHL1,KCNMB4,GSN,ADAMTS6,BACH2,ZDHHC15,IL6ST,ITPKB,KCNH2,STMN1,HECTD2,ZNF827,PDE4D,TMIE,SLC25A23,PPM1B,CEP97,BEND5,RGS3,SATB1,SBF1,ZNF821,GALNT10,FAM102A,ST6GAL1,DZIP1,ST8SIA1,TET1,PJA1,SLC44A1,BHLHB9,RUNDC3B,SSBP2,TTC3,SPATA13" Coexpression Atlas GSM538303_500 "NK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3" "Immgen.org, GSE15907" 4.10E-03 1.00E+00 1.37E-02 1.24E-01 60 414 "AS3MT,ADORA2A,KCNAB2,GAS7,CDC14B,INSYN2B,BAIAP3,CAMK2B,ARHGEF1,CD38,ARHGEF2,CHN2,OSBPL3,RIPOR2,PITPNC1,CPEB2,DOCK2,FAM78B,TSPAN5,FRY,TNK2,CERCAM,NCALD,RASL12,EYA1,ST3GAL6,OLFM1,AGAP2,FYN,MALT1,PRRC2B,GP1BB,PADI2,ZDHHC15,IRF8,ITGAM,PIK3AP1,TM6SF1,ABCB1,PLTP,PPP3CC,CASTOR1,OXR1,ATP8B4,KCNIP3,PEAR1,RASA3,SGK1,ELMO2,ST5,SULF2,KLHL4,FRYL,PIK3R5,WBP2,TRIO,LAT2,PLSCR4,ADAMTS10,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.13E-03 1.00E+00 1.38E-02 1.25E-01 10 38 "DLL3,SRRM4,IGFBPL1,INSM1,TAGLN3,KLHDC8A,HES6,SOX11,TCF12,PCBP4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 4.13E-03 1.00E+00 1.38E-02 1.25E-01 10 38 "DLL3,SRRM4,IGFBPL1,INSM1,TAGLN3,KLHDC8A,HES6,SOX11,TCF12,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k3 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.19E-03 1.00E+00 1.40E-02 1.27E-01 14 63 "PHYHD1,CACNA2D1,SEMA3D,PDLIM5,GFRA2,PCDH17,GHR,FERMT2,PDE3A,REV3L,ERCC6L2,RGMB,TRPS1,MSRB3" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k1_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.19E-03 1.00E+00 1.40E-02 1.27E-01 14 63 "BACH1,RUNX1T1,COL9A1,HAPLN1,MEX3B,LPAR4,CHIC1,GPR85,ZKSCAN3,SULF2,KLHL4,ASXL3,STXBP4,SSBP2" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_100 kidney_P0_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.19E-03 1.00E+00 1.40E-02 1.27E-01 14 63 "AMPH,IL33,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,ETV1,EYA1,IGSF5,HAS2,ROBO2,SALL1" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_500 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.19E-03 1.00E+00 1.40E-02 1.27E-01 26 147 "KLHL13,PPP4R4,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,AFF2,ZMAT1,KLHL23,KITLG,SERPINI1,RNASEL,ZFHX4,HUNK,SLC4A3,KDM3A,UHRF1BP1L,ADGRL3,ACTR6,PCDH20,LYPD6,WNK3,DPF3" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_100 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.20E-03 1.00E+00 1.40E-02 1.27E-01 17 83 "LGR5,SLC16A4,DOCK4,SCRN1,DRP2,MRO,PTK2B,CAMKK2,PPARGC1A,GPR37,KLHL23,KITLG,ADGRL3,ZFPM2,ACTR6,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_100_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.20E-03 1.00E+00 1.40E-02 1.27E-01 17 83 "CALB1,RGN,CRLF1,FAM149A,SLC35F1,MFAP3L,SMC2,KITLG,PIK3C2A,KANSL1,RASGRF2,RET,SCN8A,RPRM,UGT8,VLDLR,VSNL1" Coexpression Atlas GSM538271_100 "Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.20E-03 1.00E+00 1.40E-02 1.27E-01 17 83 "FMNL2,ADCY6,ADAM23,CDH2,FAM189A2,SLC4A8,PLXNC1,ZMYND15,INSM1,ASPRV1,PFKFB3,SEMA6D,CCDC88A,SAMSN1,TMEM150C,ARC,PHF24" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_500_J DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.22E-03 1.00E+00 1.40E-02 1.27E-01 57 390 "NDRG2,APC,MYOM1,NRP2,DST,CACNA2D1,CHGB,ABI3BP,GDA,CNTNAP2,MFAP3L,SPOCK3,DMPK,CPEB2,HIPK3,ELN,MRVI1,NRN1,TUBB3,FHL1,GALNT15,IGSF5,LYVE1,PRUNE2,STMN2,TPPP,GSN,IFI16,IL6ST,MAP4,MBP,MYH3,NEFM,NFE2L2,NPTX2,PRKCB,MAPK10,PRPH,RET,RYR3,SCN7A,STUM,SH3BGR,FHOD3,SLC14A1,SNAP25,DBNDD2,TLR4,TNS1,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,AGMO,DOCK8,MSRB3" Coexpression Atlas Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-B Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-B Lungmap CCHMC 4.26E-03 1.00E+00 1.42E-02 1.28E-01 40 254 "NDRG2,AGT,ARHGEF2,NRXN3,ABI3BP,RBM39,CST3,DBT,YTHDC1,EDNRA,EDNRB,PHF20L1,FGFR1,GLUL,GSN,GUCY1A1,HLF,IL6R,KCNK3,MARK3,MBNL1,PCSK5,PDE4B,ENPP2,PIK3R1,FXYD1,PMP22,SCHIP1,SEPT4,RBBP6,MEG3,CLIP1,LIMCH1,PDZRN3,PRRC2C,ENHO,TPM1,SSBP2,ZBTB38,TUBA1A" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_100 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.28E-03 1.00E+00 1.42E-02 1.29E-01 18 90 "ADD1,CALM1,RBM39,RNF14,DBI,DBN1,DNM1L,TUBB3,FGFR1,STMN2,GRB10,NEFM,NNAT,GNG2,MEG3,SNRPN,PUM2,PCBP4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k4 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.28E-03 1.00E+00 1.42E-02 1.29E-01 18 90 "SORCS2,SEMA6A,DPP10,SEMA4G,CACNA1B,KALRN,BRINP1,MEGF11,SYT17,KIAA1958,ASPRV1,MSI1,ARMH4,HES6,ZFP2,IFT122,SZT2,TIAM1" Coexpression Atlas mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3 mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3 Gudmap RNAseq 4.36E-03 1.00E+00 1.45E-02 1.31E-01 159 1266 "SYN3,NCKAP5,CCDC85A,USP31,SORCS2,TRMT9B,AMPH,AMT,FGD2,EPB41L5,NT5C3B,CADPS,SLC4A4,ALDH7A1,KIF1A,RGS9,BID,BMPR1B,SYNJ2,SCAPER,MYRF,DDR1,THSD7A,KALRN,MAGI1,TBRG4,CBARP,B4GALT6,SLIT2,MYL6B,TMEM184B,CNR1,PCYT1B,ABI3BP,FAM171B,HAPLN1,CNTNAP2,FAM169A,LONRF1,TMEM170A,DAPK1,DAPK3,SPOCK2,BRINP1,DBI,AIF1L,SGSM2,SLC29A4,DPP6,DTNA,DUSP9,EDN1,SEMA3D,EIF4G1,RGS17,ERBB2,ERCC2,TBC1D16,FGF13,FGFR3,BAIAP2,PRKAG2,FOXO3,C2orf88,PDLIM5,FUT9,SYT17,TUBGCP4,PPARGC1A,DHRS4,KIAA1958,KDM2B,KCNMB4,LNX1,STON1,STMN2,GRB10,GRIK5,FAM222A,FRMD5,NEGR1,FAM69A,SMAD9,MATN2,MEIS1,PPM1L,SAMD5,MSI1,BLOC1S2,MXI1,MYCN,LYRM9,NME4,VWA2,KSR2,PDE1C,PLCD1,PLXNB1,EPB41L4B,POLR2F,PRKCB,MAPK4,GDPD1,WBP1L,GDPD2,ELOVL2,PTPN13,NKAIN1,SUSD4,RADX,FIGN,RFX2,PTGR2,HUNK,SATB1,TNFRSF19,SEC14L1,SH3BGR,FERMT1,ASAP3,CNKSR2,CCDC92,PEX26,CXXC4,SMARCD3,INAVA,KIF13A,SOX11,ZSWIM8,SPTB,ZC4H2,KANK1,COBL,SYT5,FBXW11,CUX2,TRIM2,AKTIP,RELL2,BEX4,SYNPO2,HSPBP1,SGK3,UBC,UCHL1,CCDC14,WNT7A,ATP6V0E2,NDRG4,LYPD6,DPYSL5,SH3GLB2,MEIS3,SLC38A1,SEMA3B,KCNAB1,WNK2,FZD3,DPF3" Coexpression Atlas gudmap_kidney_adult_CortVasc_Tie2_k2_1000 kidney_adult_CortVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.42E-03 1.00E+00 1.46E-02 1.33E-01 46 302 "RALGAPA1,ADGRF5,SPARCL1,SEMA7A,PI16,LGR5,ATP1B3,ADAM15,CFLAR,CH25H,LDB2,CD38,LRRC3B,PPP1R16B,EDN1,EDNRB,TMTC1,CALCRL,F8,FLT1,PDLIM5,INPP5K,PCDH17,GGTA1P,STMN2,SCIN,ITPKB,LIFR,LMO2,TM6SF1,MEIS2,MX1,SLC10A4,CYTL1,PLTP,MINDY2,SNRK,PTPRB,C1orf54,SGK1,LIMS2,SLC14A1,PLCB1,SYNE1,TEK,PLSCR4" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k4_500 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.43E-03 1.00E+00 1.47E-02 1.33E-01 27 155 "ACTN1,NDRG2,SPARCL1,ALDH7A1,MYOM1,DCLK1,NDST3,DMD,EDIL3,EDNRA,HEYL,CERCAM,ABCA8,FHL1,IGSF5,HSPA1L,SLC6A17,MEF2C,NTRK3,RELN,FIGN,SALL1,SH3BGR,SLC4A3,TPM2,KCNAB1,RGS7BP" Coexpression Atlas ratio_SC_vs_MESO_1000_K3 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 4.45E-03 1.00E+00 1.47E-02 1.34E-01 29 170 "ZFYVE28,PLA2G4C,LDB2,UBE2L6,ABCG2,ARHGEF6,SNCAIP,PLPPR4,DOCK2,EBI3,CALCRL,LRRC17,CGREF1,ST6GALNAC3,DISP2,CREG2,MAP2,MX1,LAYN,NOVA2,TMOD2,NALCN,KLK6,PTPRN2,BAALC,FERMT1,SLC37A2,TCF4,SLC35G2" Coexpression Atlas GSM854322_500 "Myeloid Cells, MF.Medl.SLN, CD11b+ CD169+ F4/80+, Lymph Node, avg-2" "Immgen.org, GSE15907" 4.46E-03 1.00E+00 1.47E-02 1.34E-01 57 391 "MTUS1,ABCD2,APOC2,ATP1A3,CD86,SCARB1,CD38,UBE2L6,B4GALT6,LY86,GDA,CSF1R,CSF2RA,VCAN,CST3,CYBB,MYADM,DGKG,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,OLFM1,FOLR2,GCNT2,GFRA2,LYVE1,IRAK3,HP,IFI16,IGF1,LRRC25,IL6R,ITGAM,LAMP2,LIFR,PIK3AP1,MSR1,P2RY13,NCF2,SMOX,PLTP,PMP22,PILRA,DRAM2,RASGEF1B,MARCH1,PID1,SLC11A1,RGL1,SULF2,PLCB1,TLR4,TRIO,P2RY12,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200_k4 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.50E-03 1.00E+00 1.49E-02 1.35E-01 13 57 "MYOM1,PRUNE2,BVES,HNMT,NPTX2,RYR3,STUM,FHOD3,DBNDD2,ENHO,PPIL6,RBFOX3,ACTR3B" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_100 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.58E-03 1.00E+00 1.51E-02 1.37E-01 8 27 "DOCK4,DRP2,EMX2,NRN1,KLHL23,KITLG,SLC4A3,ACTR6" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_200 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.58E-03 1.00E+00 1.51E-02 1.37E-01 8 27 "RUNX1T1,CBLN1,EYA1,PLTP,PTCH1,TMEM255A,VSNL1,STOX2" Coexpression Atlas JC_iEC_1000_K4 JC_iEC_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 4.60E-03 1.00E+00 1.52E-02 1.37E-01 26 148 "GALNT13,TMEM108,HAP1,DLGAP1,AKAP5,CRYBB1,AIF1L,PIPOX,IGSF5,GNG4,LINGO1,MIER3,CHST6,SALL1,SCN8A,PREX2,RHBDL3,SYT1,PCDHA6,IL34,UGT8,MGAT5B,VGF,VSNL1,KCNK12,LYPD6" Coexpression Atlas PCBC_ratio_DE_vs_SC_500 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500 PCBC 4.62E-03 1.00E+00 1.52E-02 1.38E-01 70 499 "KCNH8,ACHE,MTUS1,ARHGAP20,PCDH10,TRMT9B,LGR5,ARRB1,ARSE,CFLAR,C5,IL33,LDLRAD4,CDH2,CRHBP,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,LYPD1,SPOCK3,DLC1,AMOTL2,FLNC,C2orf88,RASL10A,CHL1,GAD1,FREM1,PCDH17,FAM222A,HAS2,CDH20,KCNF1,MATN3,LRP1B,SAMD5,NBL1,PAX6,GPSM2,PDZRN4,RASGEF1B,RELN,PTH1R,ELOVL2,ACSS3,FAM184A,PRIMA1,ZFHX4,CCDC92,SMARCD3,MCF2L2,NFASC,SULF2,TMEM150C,ZFPM2,RIMBP2,PIK3R5,TRPM2,RPRM,PDIA2,FLRT2,TOM1L2,KCNK12,ANKS1B,MEIS3,ADAMTS9,PLSCR4" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K3 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 4.66E-03 1.00E+00 1.53E-02 1.39E-01 75 541 "ADD1,USP31,OSBPL8,BEGAIN,AMPD2,SMIM29,UPRT,SLC25A14,KYAT1,METTL6,LRBA,B4GALT6,MAGED1,ABCG1,OSBPL3,APPL1,DCAF4,LONRF1,ARMCX2,DCTN1,DMPK,ABCC5,ANKRD46,TNK2,STARD3NL,IGSF6,MEX3B,SLC37A3,POMT1,ERGIC3,DHRS4,TXNL4A,COPS8,KCNMB4,GPT2,GSN,ZBTB49,RASSF8,ACOT7,MSL1,STMN1,CHIC1,SRSF12,NNAT,TBC1D25,KCTD15,SMIM7,ANKRD16,NECAB2,MBOAT7,PRKACB,PEX2,ZSCAN2,KIF7,KLHL11,RNH1,ZNF532,ZNF354C,HES6,ZNF821,FOXRED1,FAM102A,KANSL3,ARFGAP1,ZC4H2,EXOC7,DNMBP,TMEM121,TIAM1,TMEM9,HEY1,CA14,MTCH1,ITM2C,FAM219B" Coexpression Atlas GSM538380_500 "alpha beta T cells, T.4Nve.PP, TCR+ CD4+ CD44low CD62Lhigh, Peyer's Patch, avg-2" "Immgen.org, GSE15907" 4.68E-03 1.00E+00 1.54E-02 1.40E-01 49 327 "ACTN1,NDRG3,NDRG2,AXIN2,ESYT2,SFMBT2,ATP1B3,LRIG1,IPCEF1,KIAA0040,RIPOR2,RASGRP1,PHF20L1,RASGRP2,FYB1,FYN,RAPGEF6,GGT5,BACH2,ZDHHC15,AGFG1,IL6R,IL6ST,INPP1,ITPKB,HECTD2,PDE4D,RETREG1,SH3KBP1,PPP3CC,TTC13,CEP97,REV3L,CLIP1,SATB1,GALNT10,SGK1,FAM102A,DZIP1,ST8SIA1,TET1,DOP1A,SP4,ACTR6,RGMB,TRIO,RUNDC3B,RICTOR,KLHDC1" Coexpression Atlas Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(1) Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(1) Lungmap CCHMC 4.70E-03 1.00E+00 1.54E-02 1.40E-01 47 311 "LTBP4,APC,DYNLL1,NRP2,DST,CA8,THSD7A,SPAG9,LDB2,COPB2,CNN3,MAGED1,CST3,PNPLA8,EDN1,ELN,TUBA1B,FCGRT,FLT1,NSG1,PCDH17,LYVE1,FERMT2,KTN1,LMO2,MEIS2,MEST,KITLG,PCSK5,CCSER2,PMP22,PPP3CA,RELN,PTPRB,PTPRG,PTX3,RDX,UNC5B,KANK1,KLHL4,TCF4,TEK,TUBB2A,UBC,WRN,TUBA1A,ITM2C" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_1000_k2 DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.70E-03 1.00E+00 1.54E-02 1.40E-01 46 303 "HECW2,ADGRF5,NRP2,ARHGEF7,SCARB1,CD38,PPP1R16B,CYBB,ELMO1,SEZ6L2,EDNRB,EBI3,CALCRL,EPHB1,CORO2B,DLC1,FLT1,TRIM16,PCDH17,LYVE1,LPAR4,ICA1,IGF1,KIT,LMO2,MEF2C,MEIS2,MSR1,MYO7A,NCF2,SNRK,PTPRB,TMEM255A,RGS3,SGK1,FAM102A,PREX2,ARHGAP26,THSD1,SLC37A2,TAL1,AMZ1,GDPD5,PLD4,DOCK8,SPATA13" Coexpression Atlas gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K4 gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K4 Gudmap RNAseq 4.70E-03 1.00E+00 1.54E-02 1.40E-01 57 392 "ACHE,ADCY6,ADD2,C1QTNF1,ARRB1,PDE8B,NRP2,GPR146,UBE2L6,QKI,AATK,CST3,RIPOR2,EBF1,EDN1,FRY,OPTN,RASGRP2,ST3GAL6,CHST15,FCGRT,FGF1,ERAP1,FERMT2,CCDC184,GSTM5,IFI16,IL6ST,INPP5B,ITPKB,KCNJ5,KIFC3,MAPT,MMP17,MX1,LAYN,P2RX7,PDE3A,SERPINI1,PLEC,SEPT4,ZDHHC14,EMID1,PEAR1,PREX2,CPEB4,UNC5B,DBNDD2,RGL1,TACC1,PDLIM2,TNS2,ENHO,TLR4,TNS1,IL34,MSRB3" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k5 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.76E-03 1.00E+00 1.56E-02 1.42E-01 25 141 "WDR35,TAOK1,C1QTNF3,SPARCL1,ARHGAP20,LTBP4,PTCH2,JAZF1,PLCXD3,RIPOR2,ELN,LRRC17,CSDC2,LAMA2,MATN2,MEF2C,NRBP2,NDP,NFIX,CLDN11,FXYD1,TACC1,RASD2,NPL,NR2C2" Coexpression Atlas GSM854326_100 "Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3" "Immgen.org, GSE15907" 4.84E-03 1.00E+00 1.59E-02 1.44E-01 18 91 "LY86,CRYBB1,CSF1R,TLR7,FCGR1A,HPGDS,GLUL,GPR34,ITGAM,P2RY13,PMP22,GAL3ST4,SALL1,SLC2A5,SLC11A1,P2RY12,AGMO,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.84E-03 1.00E+00 1.59E-02 1.44E-01 27 156 "OGT,APC,BMP7,CLCN3,RBM39,ARHGAP24,DDX46,SEMA3D,EIF5,EIF1,SYNCRIP,SMC2,PDLIM5,PPARGC1A,CNTRL,GRB10,ICA1,NEK1,PIK3C2A,KANSL1,REV3L,CLIP1,STX1A,ERCC6L2,SSBP2,VLDLR,ZNF23" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_200 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.84E-03 1.00E+00 1.59E-02 1.44E-01 27 156 "HECW2,ADGRF5,SPARCL1,CD38,HAPLN1,ELMO1,EDNRB,CALCRL,FLT1,PDLIM5,FYB1,PCDH17,LPAR4,LMO2,TM6SF1,MEF2C,PTPRB,TMEM255A,C1orf54,SEMA6D,PREX2,LIMCH1,THSD1,KLHL4,TEK,HEY1,NAV3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.85E-03 1.00E+00 1.59E-02 1.44E-01 19 98 "KDM5D,AMH,CADPS,MRO,PLXNC1,FAM198B,PTK2B,FGF13,IQGAP2,GATM,PPARGC1A,ADGRA3,RASGEF1B,MASP1,ROBO1,GLDN,THRA,ADAMTS9,WNK3" Coexpression Atlas GSM854322_100 "Myeloid Cells, MF.Medl.SLN, CD11b+ CD169+ F4/80+, Lymph Node, avg-2" "Immgen.org, GSE15907" 4.86E-03 1.00E+00 1.59E-02 1.44E-01 14 64 "LY86,GDA,CSF1R,VCAN,CYBB,IGSF6,SIRPB1,FCGR1A,HP,ITGAM,MSR1,P2RY13,PILRA,PLD4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k4 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.86E-03 1.00E+00 1.59E-02 1.44E-01 14 64 "PCDH10,RUNX1T1,SLC35F1,ERC2,SCRN1,BRINP1,FOXF2,MEGF10,PCDH17,IFI16,GPR85,ZFHX4,ANKRD6,RPRM" Coexpression Atlas ratio_DE_vs_SC_1000_K5 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 4.88E-03 1.00E+00 1.59E-02 1.44E-01 75 542 "KCNH8,ACHE,PCDH10,TRMT9B,APOC1,LGR5,ARRB1,ARSE,ZBTB10,CASTOR3,C5,BAIAP3,CALB1,CDH2,CRHBP,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,ARHGAP24,ELMO1,LYPD1,SPOCK3,ERBB4,RASL10A,CAMKK2,GAD1,GATM,FREM1,PCDH17,GNAL,GPR37,GSTT2,FAM222A,HAS2,CDH20,KCNF1,KIT,MATN3,LRP1B,RTL5,MYT1,PAX6,JAKMIP1,PDZRN4,PPP2R2C,RASGEF1B,MAPK10,ELOVL2,RIPOR1,SLC25A48,ACSS3,FAM184A,PRIMA1,ZFHX4,ANKRD6,PEG10,MCF2L2,NFASC,SULF2,TMEM150C,RIMBP2,PIK3R5,TRO,TRPM2,TUBB2A,RPRM,PDIA2,VLDLR,KCNK12,PCDH20,ANKS1B,MEIS3,FAM13C,CASC15" Coexpression Atlas gudmap_kidney_e15.5_Podocyte_MafB_k4_100 kidney_e15.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.88E-03 1.00E+00 1.59E-02 1.44E-01 5 12 "VCAN,IGSF5,FREM1,HAS2,SALL1" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K1 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.90E-03 1.00E+00 1.60E-02 1.45E-01 35 217 "KIAA1324,ARHGAP20,ZFYVE28,PDE8B,ADGRB2,LDLRAD4,KCNAB3,VAX2,CSF1R,DRP2,SNX29,RASA4,DLL3,FYB1,TMEM8B,LYVE1,GNG4,GUCY1B1,GPR155,NEXMIF,NPR2,PLCL1,TRHDE,PRKAR1B,ZCWPW1,ZNF493,ZMAT4,PRIMA1,STK32B,MRAS,ASAP3,FAM189A1,KCNE5,CADM2,DPF3" Coexpression Atlas seminal vesicle seminal vesicle Human Protein Atlas 4.92E-03 1.00E+00 1.60E-02 1.45E-01 24 134 "PTCHD1,PCDH10,CPNE6,CHRDL1,EDNRA,TMEM35A,EMX2,RASL12,MYH3,NEFM,PDZRN4,NWD1,CRTAC1,ZFHX4,FHOD3,UNC5B,STAC2,ARC,RASD2,SYNPO2,CA14,VIPR2,RBFOX3,PRDM8" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k2_100 kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.95E-03 1.00E+00 1.61E-02 1.46E-01 9 33 "CRYM,SNCAIP,VCAN,SNAP91,EYA1,FGFR1,HAS2,CNTN3,SALL1" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_200_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.97E-03 1.00E+00 1.62E-02 1.47E-01 11 45 "LCORL,RBM39,CHIC1,KITLG,TMLHE,FNIP1,CPEB4,CBX5,R3HDM1,SSBP2,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_500 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.01E-03 1.00E+00 1.63E-02 1.48E-01 56 385 "ACADM,ADORA1,AMPH,LGR5,ASPA,ATP1A1,CA4,CA8,CA12,CLDN10,RBM39,OSBPL3,GREB1,ARHGAP24,FAM107B,DUSP9,EMX2,ST3GAL6,FGFR3,SEMA4D,PDLIM5,FUT9,MTHFD2,IGSF5,CBX1,GPD1,GUCY1A1,SCIN,CLEC18A,OXTR,RETREG1,SCHIP1,IRX1,LAMA1,ELOVL2,PTPN13,PTPRO,ZDHHC14,RDX,RET,FHOD3,DDN,RGL1,PRRC2C,COBL,SATB2,TRIM2,HEY1,NPL,AMACR,SGK3,UGT8,STOX2,TMEM178A,VPS35L,SPATA13" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k3_500 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.04E-03 1.00E+00 1.64E-02 1.48E-01 26 149 "TMEM108,MYRF,CALB1,CNTFR,AKAP5,CLIP3,DNM1,C8orf37,FLNC,BVES,TCEAL6,KCND2,MAP2,MATN2,MEIS1,NEFM,NME4,PCDH18,PTN,RADX,KCNIP1,PKNOX2,ZFPM2,ASXL3,TRPS1,PLEKHH2" Coexpression Atlas gudmap_kidney_adult_GlomCapSys_Tie2_k2_500 kidney_adult_GlomCapSys_Tie2_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.04E-03 1.00E+00 1.64E-02 1.48E-01 26 149 "HECW2,PI16,ARNTL,NUMB,CFLAR,ANKRD44,CSF1,LRRC3B,PITPNC1,EDN1,KLHL5,DLC1,PDLIM5,INPP5K,STMN2,LIFR,MSR1,P2RY1,PTPRG,C1orf54,SCN7A,SGK1,DBNDD2,SYNE1,TLR4,LYPD6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 5.05E-03 1.00E+00 1.64E-02 1.49E-01 10 39 "RGS17,EMX2,RRAGB,FGF12,KHDRBS3,FUT9,TPPP3,PCLO,PAX6,LMO3" Coexpression Atlas gudmap_kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_Scamp_k1_1000 kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.08E-03 1.00E+00 1.65E-02 1.49E-01 67 476 "EMILIN3,ELFN2,PWWP2A,ADRA1D,DOC2A,LRFN1,PPFIA4,SUGT1P4-STRA6LP-CCDC180,ATP1A3,BAIAP3,THSD7A,P2RX6,CBFA2T2,CBARP,QKI,IGLON5,COL9A3,COL11A2,FAM171B,ARHGEF4,HDAC9,ARHGAP32,GRIN3A,HS3ST2,MAMLD1,EGR3,DENND4A,REEP2,GTF2IRD2,GRIK5,SERP2,SLC2A6,IGFBPL1,LRRC75A,ITPKA,KCNB1,PPM1L,MMP16,MMP17,MYO9A,NCF2,SNX10,VSTM2L,KIF7,MAPKBP1,TMCC1,SOX3,ARHGAP26,NFASC,SST,SSTR1,SYNE2,ADAMTS17,SZT2,TIAM1,TNS1,CHST5,TRIO,PLEKHH2,MGAT5B,PLPPR2,REEP1,SLC30A3,GDPD5,ADAMTS9,SLC17A7,WNK2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.11E-03 1.00E+00 1.66E-02 1.50E-01 7 22 "CADPS,ZNF804A,GABRB3,NEFM,EML5,CUX2,FSTL5" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k4_500 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.11E-03 1.00E+00 1.66E-02 1.50E-01 7 22 "DOCK4,FAM198B,KITLG,LAYN,RASA3,DOCK9,ADAMTS9" Coexpression Atlas Lungmap Mouse Lung E16.5 Endothelial Subtype Matrix Endothelial Lungmap Mouse Lung E16.5 Endothelial Subtype Matrix Endothelial Lungmap CCHMC 5.12E-03 1.00E+00 1.66E-02 1.50E-01 59 410 "DYNLL1,N4BP2L1,NRP2,DST,GPC2,LDLRAD4,CFAP410,CERS5,ARHGEF2,CCPG1,TBRG4,ABI3BP,CRMP1,SEC24C,HDAC9,ARHGAP24,MATR3,TMEM170A,SPATA2,ALKBH8,EDNRB,KLHL5,PLXNC1,EIF4G2,HSPA12B,FHL1,COQ5,ST6GALNAC3,GFER,DIDO1,MUM1,HMGCL,ICA1,KCNK3,KTN1,STMN1,MAN2A2,MARK3,TM6SF1,LAYN,CCSER2,SCHIP1,MAPK3,SNRK,RDX,ADAL,RPS6KA2,SGK1,LIMS2,SPTAN1,CAMTA1,TAL1,USP22,BEX4,C9orf85,WIPF1,ZBTB14,REEP1,TUBA1A" Coexpression Atlas GSM854312_100 "Myeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 5.13E-03 1.00E+00 1.66E-02 1.50E-01 15 71 "GDA,CSF1,IGSF6,SIRPB1,FCGR3A,GCNT2,HP,ITGAM,SFXN5,ASPRV1,P2RY13,PILRA,SLC11A1,DMXL2,TLR4" Coexpression Atlas GSM605868_100 "Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4" "Immgen.org, GSE15907" 5.13E-03 1.00E+00 1.66E-02 1.50E-01 15 71 "ATP1A3,LY86,GDA,CSF1R,CYBB,IGSF6,TLR7,SIRPB1,FCGR1A,ITGAM,MSR1,PILRA,PID1,SLC11A1,PLD4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.13E-03 1.00E+00 1.66E-02 1.50E-01 15 71 "NDRG2,SPARCL1,ALCAM,CDO1,LYPD1,DPP6,EDNRB,ADGRV1,TPPP3,CFAP126,NRBP2,NTRK2,NKAIN4,PTN,SULF2" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000_k1 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.18E-03 1.00E+00 1.67E-02 1.52E-01 34 210 "RNF157,PCDH19,SEMA6A,EPB41L5,CASK,CH25H,CDH2,NSL1,PYGO1,MTX3,SLC9B2,PRELID3A,CHL1,BRD8,PRDM5,HAS2,LIG4,MID1,PCDH8,GPR85,CEP41,GAL3ST4,CRTAC1,FIGN,HUNK,SALL1,ANKRD6,SLC9A5,CEP68,CCDC14,XPO1,ZNF24,PHTF2,NETO2" Coexpression Atlas gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_200 kidney single cell_e11.5_MetanephMesench_StemCellamp_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.23E-03 1.00E+00 1.69E-02 1.53E-01 25 142 "MTUS1,TMEFF1,ARHGEF25,CNTFR,COL9A1,ZNF521,CSNK1E,EBF1,FGF13,SMC2,PSIP1,MEIS2,MEST,SAMD14,MYCN,PTN,C1orf54,TSPY26P,MEG3,SOX11,CUX2,C18orf54,ENHO,PCBP4,NETO2" Coexpression Atlas gudmap_developingKidney_e15.5_Medullary collecting duct_500 DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.24E-03 1.00E+00 1.69E-02 1.53E-01 57 394 "OGT,APC,EPB41L5,SFMBT2,PDE8B,ATP1A1,RGS11,CALB1,HIP1R,USP2,CLCN3,FAM149A,RBM39,CRYM,IPCEF1,AIF1L,MFAP3L,SNX29,SEMA3D,EIF1,ENO2,EPB41,SUCO,APOPT1,GALC,IGSF5,PPARGC1A,CCDC184,GRB10,GSTT2,PADI2,SCIN,SLC35G1,KCNJ16,KIF2A,L1CAM,AQP11,SCAMP5,MKLN1,PIK3C2A,JAKMIP1,PLXNB1,MBOAT7,KANSL1,DPF2,REV3L,EMID1,SCN8A,NAPB,MYCBP2,ATP10B,STX1A,ERCC6L2,RGMB,SSBP2,UGT8,LYPD6" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_100 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.31E-03 1.00E+00 1.71E-02 1.55E-01 16 78 "AMPH,VAT1L,CACNA2D1,CACNB4,RBM39,CRYM,DYNC1I1,EYA1,FGF1,FAM19A2,FAM107A,HAS2,FRMD3,SALL1,ANKRD6,ERCC6L2" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K3 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 5.32E-03 1.00E+00 1.71E-02 1.55E-01 46 305 "NDRG2,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,CACNA1B,CBARP,MYL6B,LETMD1,MYADM,SPOCK2,SEMA3D,EGFR,FGF11,FGF12,SYT3,STAMBP,TPPP3,TVP23A,PCDH17,FAM107A,FRMD3,LRRC75A,MEIS1,MOV10,SAMD14,HS6ST3,GPR173,SMOX,FXYD1,NECAB2,EMID1,ATXN7,FERMT1,DOK5,UNC5B,ADAMTS17,MCF2L,SLC44A1,CA14,TOM1L2,NDRG4,SH3GLB2,ADAMTS9,NAV3" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_100 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.35E-03 1.00E+00 1.72E-02 1.56E-01 6 17 "ARHGAP20,CBLN1,VCAN,EDNRA,FREM1,GUCY1A1" Coexpression Atlas gudmap_kidney_e10.5_UretericTrunk_HoxB7_k1_1000 kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.44E-03 1.00E+00 1.75E-02 1.59E-01 37 234 "PCDH19,LCORL,SUGT1P4-STRA6LP-CCDC180,MTMR7,B4GALT6,SLIT2,HAPLN1,FAM169A,HDAC4,DUSP9,E2F5,PLEKHA1,EMX2,FDFT1,PSD2,C2orf88,C15orf41,MAP7D2,FAM19A2,SLC35G1,CHIC1,KITLG,TCEAL5,NRCAM,EML5,TUG1,TMEM255A,RET,NUDT11,SHMT2,NUDT10,BEX4,DCBLD1,RPRM,UCHL1,VSNL1,ZNF711" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k3 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.45E-03 1.00E+00 1.75E-02 1.59E-01 18 92 "CH25H,RUNX1T1,DCLK1,PCYT1B,CRYM,EYA1,POLR1B,UBE2E3,MEGF10,GNG4,IFI16,PCDH8,GPR85,CEP41,ZFHX4,SALL1,CSRNP3,KCNAB1" Coexpression Atlas GSM791126_100 "Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3" "Immgen.org, GSE15907" 5.45E-03 1.00E+00 1.75E-02 1.59E-01 18 92 "ZNF608,CDC42BPA,PRC1,CALCRL,MED12L,NBEA,GCNT2,GRB10,GUCY1A1,HLF,ICA1,KIT,LMO2,MEIS1,MYCN,TET1,TEK,NETO2" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500_k5 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.45E-03 1.00E+00 1.75E-02 1.59E-01 18 92 "LGR5,INSYN2B,CALB1,CNR1,RASGRP1,GATM,MAP7D2,KCND2,KITLG,MYO5A,NEXMIF,SERPINI1,PRCD,CPEB3,SYBU,CPEB4,ANKRD12,DMXL2" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_200 dev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.45E-03 1.00E+00 1.75E-02 1.59E-01 30 180 "HECW2,ADGRF5,SPARCL1,CBLN1,SCARB1,CD38,HAPLN1,ELMO1,EDNRB,CALCRL,FLT1,PDLIM5,FYB1,PCDH17,LPAR4,LMO2,TM6SF1,MEF2C,PTPRB,TMEM255A,C1orf54,SEMA6D,PREX2,LIMCH1,THSD1,KLHL4,TEK,HEY1,VSNL1,NAV3" Coexpression Atlas ratio_SC_vs_ECTO_1000_K1 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 5.54E-03 1.00E+00 1.77E-02 1.61E-01 73 528 "ADCY8,PTCHD1,PDZD4,CARMIL3,CALB1,CBS,DCLK1,CHRNA4,FAM189A2,FAM19A5,CRYBB1,GALNT9,VCAN,RIMS4,KIF26A,KCTD8,BRINP1,HS3ST2,AASS,PIPOX,PPP1R1B,OLFM1,HPCAL4,FLT1,CSPG5,MEGF11,MEGF10,HRASLS5,GABRB3,GCK,GNG4,LINGO1,HNF4G,LRRC75A,KCND2,KCNN1,KCNN2,KHK,KIF5A,CAMK2N2,MYCN,FXYD7,NPTX2,JAKMIP1,EPB41L4B,PPP2R2B,PPP2R2C,PRODH,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,RORB,MRAP2,PREX2,SEPHS1,OGDHL,SNRPN,HECW1,UNC5B,SEPT3,NECAB1,RHBDL3,SYN1,ARC,TACR1,KLHL4,CHST8,ENHO,IL34,UGT8,NETO1" Coexpression Atlas gudmap_kidney_e15.5_Podocyte_MafB_k3_1000 kidney_e15.5_Podocyte_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.55E-03 1.00E+00 1.78E-02 1.61E-01 39 250 "BCL7A,BMPR1B,CACNA1G,SOCS6,SLIT2,CNTFR,CRYM,SNCAIP,VCAN,HEPH,GSDME,MTX3,E2F5,EYA1,FAM49B,IGSF5,FREM1,HAS2,ZDHHC15,NEGR1,CLEC18A,NME4,NOVA1,LAMA1,PTN,PTX3,TUG1,ERI2,MORC4,SALL1,CNKSR2,NUDT10,ADAMTS17,TAF9,CUX2,TRPS1,SLC38A1,ADAMTS9,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eSC_Subtype_eSCa_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eSC_Subtype_eSCa_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 5.56E-03 1.00E+00 1.78E-02 1.61E-01 50 338 "ACTN1,MTA3,SEMA6A,ALCAM,ADAM23,CBS,CDH2,NUMBL,FOXN3,CHN1,PLEKHB1,LRIG1,DZIP3,SCRN1,DMD,AASS,MRNIP,ADGRV1,FGF13,FGFR1,APOPT1,FERMT2,LPAR4,SOX21,PSIP1,ZIC5,IPO5,MARK3,MEST,NNAT,NME4,PRTG,PRKAB2,MAPK10,PRODH,PTPN13,GTDC1,ROBO1,SALL1,SEPHS1,SOX11,TCEA1,SLC44A1,R3HDM1,TPM1,SSBP2,TTTY15,VSNL1,ZIC2,FZD3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.56E-03 1.00E+00 1.78E-02 1.61E-01 4 8 "CADPS,PLXNA4,IGSF5,RTN1" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k4 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.59E-03 1.00E+00 1.79E-02 1.62E-01 23 128 "LCORL,RBM39,DZIP3,CALCRL,EMX2,SCML2,TUBGCP4,MIER3,KCND2,CNOT4,PDPK1,OLA1,PLEC,TMLHE,FNIP1,SLC12A2,CPEB4,SNCA,SYNE2,ANKRD12,TSC1,ZNF711,ADAMTS9" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k2_500 kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.63E-03 1.00E+00 1.80E-02 1.63E-01 14 65 "NDRG2,SPARCL1,ALDH7A1,MYOM1,DCLK1,DMD,EDIL3,EDNRA,TUBA8,TCEAL6,MEF2C,FIGN,SLC4A3,TPM2" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k4_200 kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.63E-03 1.00E+00 1.80E-02 1.63E-01 14 65 "VAT1L,CACNA1G,GSDME,IGSF5,FAM107A,TM6SF1,NPY,ROBO1,GLDN,CNKSR2,TACR1,CUX2,HEY1,SLC38A1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_200 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.63E-03 1.00E+00 1.80E-02 1.63E-01 12 52 "KLHL13,PLXNA4,EMX2,NRN1,TCEAL6,MAP2,KITLG,PCDH18,STUM,SLC4A3,ADGRL3,LYPD6" Coexpression Atlas gudmap_developingKidney_e15.5_1000_k3 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.64E-03 1.00E+00 1.80E-02 1.63E-01 55 379 "RALGAPA1,ABHD6,OGT,APC,EPB41L5,PHYHD1,SLC4A4,BMP7,MTMR3,DCLK1,CLCN3,COL4A5,NCOR1,TM9SF4,TMEM170A,MFAP3L,CPEB2,DNM1L,HIPK3,SEMA3D,EIF5,VPS13B,EZH1,SEC24B,MED12L,SUCO,SYNCRIP,SYT17,GCNT2,PPARGC1A,KIAA1958,GRB10,FAM107A,SCIN,KIF2A,MYH3,CNOT4,PIK3C2A,PDZRN4,KANSL1,REV3L,NCBP3,NAPB,CPEB4,MYCBP2,KANK1,PRRC2C,DNMBP,MGRN1,TRIM2,NSD1,SSBP2,UGT8,VLDLR,DOCK8" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.77E-03 1.00E+00 1.84E-02 1.67E-01 27 158 "PCDH10,SYT13,INSYN2B,DST,CH25H,RUNX1T1,CBLN1,DCLK1,CRLF1,SCRN1,DLX1,TMEM132C,FOXF2,MEGF10,CHL1,GFRA2,GNG4,GRIA2,MYH3,ZFHX4,SALL1,LIMCH1,SOX11,SATB2,SYNPO2,WNT7A,KCNAB1" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k5_1000 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.77E-03 1.00E+00 1.84E-02 1.67E-01 27 158 "AMH,SEMA7A,ARHGDIG,ST3GAL5,DDR1,CBLN1,PUM1,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,PTK2B,FYN,CSDC2,GPR37,TTYH2,MEF2C,MYO7A,SEMA5B,PTPRE,MEG3,ARX,SIN3B,TNS1,NR2C2,TST" Coexpression Atlas PCBC_MESO-5_fibroblast_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 5.83E-03 1.00E+00 1.85E-02 1.68E-01 126 985 "KCNH8,ADCY8,GALNT13,ADORA1,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,APOC1,LGR5,ARSE,RASL11B,KIF1A,BMP7,BTK,C5,MYRF,CACNA1B,CALB1,CBS,CCK,USP2,CDH2,L3MBTL4,PLEKHB1,FAM189A2,IGLON5,CNR1,COL9A1,COL9A3,GAL3ST1,NRG2,CRHBP,CNTNAP2,PPP1R16B,PLCXD3,ARHGEF4,ARHGAP24,SV2B,KIF19,SLC25A18,FAM78B,CNNM1,ERBB4,RASL12,ADGRV1,FGFR3,RASL10A,MEGF10,HRASLS5,GABRB3,GAD1,GATM,FREM1,PPARGC1A,GNAL,GPR37,TMEM121B,GRM2,FAM222A,HAS2,HBA1,NCKAP1L,IGFBPL1,HP,SHISA6,NKD1,LRRTM1,C2CD4C,KCND2,KCNF1,KCNJ5,KCNN1,KIT,MATN3,MYT1,IGSF11,PAX6,PCDH8,PRTG,SLC10A4,SEMA5B,JAKMIP1,PDZRN4,MAGEL2,RASGEF1B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,KHDRBS2,PRIMA1,MRAP2,SALL1,SEMA6D,TMEM200C,ST8SIA1,ANKRD6,MCF2L2,NFASC,SSTR2,TMEM150C,COBL,PHF24,FAM189A1,GALNT17,FAM124A,PIK3R5,TRPM2,CA14,RPRM,VIPR2,RBFOX3,KCNK12,ZIC2,KCNT2,ANKS1B,CADM2,GAL3ST3,DOCK8,FAM198A,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500_k4 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.88E-03 1.00E+00 1.87E-02 1.69E-01 15 72 "ZSCAN18,BMP7,SIPA1L1,CTH,KATNAL2,RAB39B,PRELID3A,KIAA1958,FAM19A2,MSI1,GAL3ST4,MAPK12,ZNF184,INTS3,PCBP4" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K3 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 5.88E-03 1.00E+00 1.87E-02 1.69E-01 15 72 "ADCY8,CA4,HAPLN1,LRRC3B,HDAC9,FGF11,ZIC5,CDH20,PRTG,FXYD1,IRX1,NKAIN4,EMID1,SALL1,ZIC2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k2 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.88E-03 1.00E+00 1.87E-02 1.69E-01 15 72 "EPB41L5,AIF1L,ST3GAL6,SYT17,IGSF5,HP,GDPD2,PTPRO,RIPOR1,FAM184A,DUSP15,DDN,TMEM150C,TNS2,TMEM178A" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k5 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.95E-03 1.00E+00 1.89E-02 1.71E-01 24 136 "NDRG2,PI16,ADAM23,SEC11C,GPR146,CAST,CLDN10,ENTPD2,FAM189A2,ABI3BP,GDA,ARRDC4,NRN1,GCNT2,LYVE1,GSN,HLF,MBP,ZDHHC14,SCN7A,HSPA4L,TIMP4,TLR4,PLSCR4" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k4_1000 kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.03E-03 1.00E+00 1.91E-02 1.73E-01 16 79 "NDRG2,CA12,CTH,EDNRA,FCGRT,FGF1,IGSF5,HSPA1L,KHK,ENPP2,PPP1R1A,PRODH,GKAP1,LIMCH1,PPIL6,NDRG4" Coexpression Atlas GSM538268_100 "Myeloid Cells, DC.IIhilang+103+11blo.SLN, MHCIIhi CD11c+ Langerin+ CD103+ CD11b-, Lymph Node, avg-3" "Immgen.org, GSE15907" 6.03E-03 1.00E+00 1.91E-02 1.73E-01 16 79 "FMNL2,ADCY6,ADAM23,UBE2L6,SLC4A8,PLXNC1,ENO2,ZMYND15,RAB30,INSM1,ASPRV1,PFKFB3,SEMA6D,CCDC88A,TMEM150C,ARC" Coexpression Atlas GSM605766_500 "alpha beta T cells, T.4FP3-.Sp, 4+ 8- GFP- 44lo, Spleen, avg-3" "Immgen.org, GSE15907" 6.07E-03 1.00E+00 1.92E-02 1.74E-01 53 364 "ACTN1,NDRG3,NDRG2,ADD1,AXIN2,ESYT2,PITPNM2,MADD,ATP1B3,GPR146,ARHGEF1,LRIG1,IPCEF1,SIPA1L1,RIPOR2,GUCD1,CDON,RASGRP1,RASGRP2,MEX3B,SARAF,FYB1,FYN,B4GALNT1,RAPGEF6,GGT5,BACH2,ZDHHC15,IL6R,IL6ST,ITPKB,L1CAM,PDE4D,TMIE,RETREG1,SLC25A23,SH3KBP1,PPP3CC,CASTOR1,CEP97,SATB1,GALNT10,FAM102A,ST6GAL1,DZIP1,ST8SIA1,TET1,LRRC8A,RGMB,TRIO,RUNDC3B,SSBP2,KLHDC1" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_100 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_100 FaceBase_RNAseq 6.08E-03 1.00E+00 1.93E-02 1.75E-01 19 100 "SRSF11,LHX2,IGDCC3,ABCG1,EMX2,CLVS1,TUBB3,SRRM4,PCLO,STMN2,SOX21,FAM107A,IGFBPL1,SHISAL1,NNAT,PAX6,RTN1,NR2E1,DPYSL5" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.11E-03 1.00E+00 1.93E-02 1.75E-01 17 86 "CADPS,CALB1,NRXN3,CNTN1,CRYM,EPB41L2,GALC,NEGR1,CLDN11,PCDH8,KANSL1,PTPRO,PTX3,REV3L,ERCC6L2,SYNPO2,NAV3" Coexpression Atlas gudmap_kidney_e10.5_UretericTrunk_HoxB7_k3_1000 kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.12E-03 1.00E+00 1.93E-02 1.75E-01 18 93 "ADGRF5,NRP2,CA8,CD38,CHN2,SEMA3D,FLT1,GGTA1P,LPAR4,JAK2,LMO2,TM6SF1,PTPRB,THSD1,KLHL4,TEK,C18orf54,SLC44A1" Coexpression Atlas PCBC_ratio_MESO-5_from-ESC_vs_MESO-5_from-OSK-L-l-p53KD_cfr-2X-p05 Mesoderm Day 5-reprogram_NA_vs_Mesoderm Day 5-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.12E-03 1.00E+00 1.93E-02 1.75E-01 18 93 "KCNH8,LGR5,JAZF1,LARGE1,CRMP1,PPP1R16B,ERBB4,HRASLS5,FREM1,IGFBPL1,HP,KCNF1,NRCAM,PEG10,TMEM150C,KLHL4,PIK3R5,KCNK12" Coexpression Atlas JC_hmvEC_1000_K4 JC_hmvEC_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 6.12E-03 1.00E+00 1.93E-02 1.75E-01 61 430 "TMCC3,MTUS1,ADGRF5,SRPX,PLA2G4C,MARCH3,INSYN2B,SYNJ2,CH25H,LDB2,NDST3,C7orf61,SNCAIP,OSBPL3,PPP1R16B,ARHGAP24,KLHL3,TSPAN5,EDN1,FRY,CALCRL,NRN1,ST3GAL6,CHST15,TPK1,SULT1C4,LYVE1,ADAMTS6,TNFAIP8L3,MYLK2,SLC6A17,SYTL4,TM6SF1,MSR1,NRCAM,CLDN11,PDE4B,RELN,SNRK,PTPRB,PTPRE,PTX3,ZDHHC14,CRTAC1,RGS4,PEAR1,SEC14L1,SGK1,ABLIM3,SNCA,THSD1,KLHL4,DOCK9,TEK,TLR4,FLRT2,AGMO,EML6,SLC30A3,PLSCR4,ADAMTSL3" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k1 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 13 59 "COL9A1,GRIN3A,MEGF10,KCNMB4,GP1BB,INSM1,MEIS1,TAGLN3,NTRK2,PTX3,SLC9A5,TAL1,CUX2" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_200 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.13E-03 1.00E+00 1.93E-02 1.75E-01 10 40 "RGN,SLC16A4,MTSS1L,CAMKK2,PPARGC1A,GPR37,RBBP8,REV3L,ST8SIA1,ZFPM2" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_k4_100 kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 10 40 "CA8,EDNRB,SEMA3D,TMTC1,FLT1,LMO2,SLC14A1,TEK,AGMO,PLSCR4" Coexpression Atlas gudmap_developingGonad_P2_epididymis_200_k3 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 10 40 "ARHGAP20,PKP4,BACH1,ZC3H11A,EIF4G1,LPAR4,CHIC1,MEIS2,CBX5,SSBP2" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k1_500 kidney_P0_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 10 40 "ALCAM,CASK,BCHE,IL33,SPOCK2,ARRDC4,MEIS2,MMP16,SULF2,TPM2" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500_k5 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 10 40 "MEX3B,STMN2,ROBO2,ZKSCAN3,RBM26,KLHL4,CLASP1,ASXL3,TPM1,PCDH20" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_200_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.13E-03 1.00E+00 1.93E-02 1.75E-01 9 34 "AMPH,CRYM,EYA1,FAM19A2,FAM107A,HAS2,SALL1,MAPK12,ANKRD6" Coexpression Atlas gudmap_developingGonad_e16.5_testes_500_k2 DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.15E-03 1.00E+00 1.93E-02 1.75E-01 23 129 "C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,CBLN1,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,LRRC17,GPR37,MEF2C,MYO7A,SEMA5B,MEG3,ARX,SPP1,OBSL1,TNS1,TST" Coexpression Atlas PCBC_ratio_PulmonMicrovasc_vs_SC_cfr-2X-p05 Pulmonary Microvascular_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.25E-03 1.00E+00 1.96E-02 1.78E-01 212 1753 "MTUS1,HECW2,ADGRF5,SPOP,ALCAM,SRPX,PITPNM2,CDC42BPA,C6orf89,SMIM29,ARHGDIA,ARRB1,MARCH3,NUMB,INSYN2B,ADAM15,BCS1L,NRP2,BID,CFLAR,SYNJ2,AP1M1,CAST,HIP1R,PRC1,LDB2,ARHGEF1,CDC25B,LRRFIP1,CCPG1,CFL2,TAOK2,STOML1,CLTB,HOMER3,ABI3BP,ZNF521,CNRIP1,AKAP12,RNF14,ABCG1,OSBPL3,CST3,PPP1R16B,KIAA0040,GPSM1,DOCK4,ARHGAP24,RASSF2,GIT2,ELMSAN1,RUSC2,FAM107B,CD99L2,PDCD6IP,TSPAN5,EDN1,HIPK3,KLHL5,FRY,MBNL2,IRAK4,CERCAM,MRNIP,CALCRL,SLC43A2,DENND4A,SIRPB1,HSPA12B,NRN1,FAM198B,TAOK3,CHST15,FCGRT,SLC9B2,BAIAP2,AMOTL2,PRKAG2,SCARA3,FLNC,FLYWCH1,PDLIM5,TPK1,ST6GALNAC3,AP4B1,GHDC,ERAP1,INPP5K,TUBA8,GGT5,LYVE1,DHRS4,MSL3,SLC2A6,TOX2,ZHX1,TNFAIP8L3,SYNPO,C9orf129,IDH3A,IFI16,MYLK2,IL6ST,INPP1,ITPKB,KIFC3,STXBP5,LAMP2,LIFR,LIMS1,LMO2,SYTL4,NCOA7,SMAD1,SMAD9,MAN2A2,MBNL1,TM6SF1,MEF2C,DBNL,NRBP2,LAYN,MYO5A,NBL1,NFE2L2,NRCAM,NUCB2,TBC1D25,CLDN11,PALM,PDE4B,ZDHHC8,PLEC,PMP22,PPP3CC,PRKACB,MAPK3,RELN,VPS13C,SNRK,PTPRB,PTPRE,RIPOR1,FAT4,RAP1GDS1,ZDHHC14,RGS3,RGS4,RNH1,ARMC5,RPS6KA2,STK32B,CLIP1,MAPK12,PEAR1,SEC14L1,GALNT10,RASA3,SGK1,WDR37,ABLIM3,LIMS2,WDR47,FAM214B,SIRT2,SLC12A2,ANKRD36,SNCA,CMTR2,TEX2,ARHGAP26,CAMTA2,ITPRID2,THSD1,MPRIP,RGL1,DIP2A,SULF2,TACC1,DNMBP,TAL1,PDLIM2,NR2F1-AS1,SZT2,DOCK9,TNS2,SLC35G2,CYB561A3,ZMAT3,NACC2,HEY1,TLR4,TRIO,DCBLD1,UBC,FLRT2,PLPPR2,TOM1L2,NPDC1,NDRG4,ZBTB38,SPIRE1,SLC30A3,RNF103,ADAMTS9,PLSCR4,MSRB3,NHSL1,SNX14,FRMD6,NETO2,SRGAP2B" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgld_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgld_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 6.27E-03 1.00E+00 1.97E-02 1.78E-01 49 332 "NME5,CCDC146,CADPS,CDH2,CDO1,CDR1,COL4A5,ZNF521,CNRIP1,CNTNAP2,SEZ6L2,ABCA8,TMEM132C,ZMYND10,IQCG,TMEM107,PDLIM5,ERGIC3,TPPP3,GRM8,CFAP126,LAMP2,PACRG,LRP1B,MID1,SMIM11A,NUCB2,CNTN3,PAX6,ENPP2,PKM,PLTP,HYDIN,TMEM231,FAT4,RFX3,NEK11,GALNT10,KIF27,SYNE2,ADGRL3,TCF12,CCDC173,DNAH7,ZNF106,ZIC1,ZIC2,DNALI1,NHSL1" Coexpression Atlas gudmap_developingGonad_P2_epididymis_500_k5 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.35E-03 1.00E+00 1.99E-02 1.80E-01 22 122 "ADCY8,SRPX,MYOM1,RGN,DCLK1,MFAP3L,CHRDL1,EDNRA,ETV1,FGF1,GAD1,LYVE1,GLUL,MATN2,MYH3,VWA2,NPY,NALCN,LGI2,MRAP2,PCDHB9,VLDLR" Computational M15730 MODULE_11 Genes in the cancer module 11. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.06E-40 6.54E-37 6.54E-37 4.76E-36 200 540 "MTUS1,AGT,ALCAM,SRPX,AMPH,BIN1,AMT,APBA2,APLP1,FAM131A,APOC1,BCAS1,LGR5,ARHGDIG,PDE8B,ATP2B2,ALDH7A1,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA4,CA12,CACNA1A,CALB1,CALB2,HAP1,CAPN3,RHBDL1,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,CDH2,DCLK1,LARGE1,CACNA2D2,CHGB,CHN2,PLEKHB1,SLIT2,LHX2,STOML1,SULT4A1,CABP1,COL9A3,NRG2,CRMP1,CLIP3,CRYM,VCAN,CNTNAP2,ARHGEF4,RIMS2,PPP6R2,GPRASP1,SNPH,RASSF2,DBN1,ELMO1,SNAP91,PARD6A,SV2B,TMCC2,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,CELSR3,EGR3,ENO2,RCAN2,NCALD,APC2,PTK2B,CHST15,OLFM1,FGFR1,FGFR3,TRIM16,RASL10A,KHDRBS3,CSPG5,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GALC,GATM,TUBGCP4,AHDC1,RUNDC3A,GNAO1,GNG4,STMN2,GRIA2,GRIK5,FAM107A,GUCY1B1,HLF,INPP1,ITGA7,ITPKA,L1CAM,STMN1,LMO2,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NTRK2,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE4B,ENPP2,SERPINI1,PKD1,FXYD1,PLXNB1,SCHIP1,PPP1R1A,PRKACB,PKIA,PRKCB,MAPK10,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,QDPR,REV3L,RGS4,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SGK1,SH3BGR,SH3GL3,ST6GAL1,ABLIM3,BTBD3,EPN2,FAM214B,SMARCD3,SNAP25,SPP1,PEG10,TSPYL2,LMO3,SST,SSTR2,STX1A,PLCB1,ARC,SYT1,SYT5,TRIM2,SYNE1,CDH22,THRA,KAT6B,TRO,TRPM2,VGF,VSNL1,ZIC2,TRIM9,SPHK2,GDPD5,SLC17A7,PCBP4" Computational M12065 MODULE_66 Genes in the cancer module 66. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.25E-39 7.51E-36 2.87E-36 2.09E-35 201 552 "ASIC1,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,APBA2,APLP1,FAM131A,APOC1,BCAS1,LGR5,ARHGDIG,PDE8B,ATP2B2,ALDH7A1,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,CAPN3,RHBDL1,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,CDH2,DCLK1,LARGE1,CACNA2D2,CHGB,CHN2,PLEKHB1,LHX2,STOML1,SULT4A1,CABP1,COL9A3,NRG2,CRMP1,CLIP3,CRYM,VCAN,CNTNAP2,ARHGEF4,RIMS2,GPRASP1,SNPH,RASSF2,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,SNAP91,PARD6A,SV2B,TMCC2,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,CELSR3,ENO2,RCAN2,NCALD,APC2,PTK2B,CHST15,OLFM1,FGFR1,FGFR3,FOLR2,RASL10A,KHDRBS3,CSPG5,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GATM,TUBGCP4,AHDC1,RUNDC3A,GNAO1,GNG4,STMN2,GRIA2,GRIK5,FAM107A,GUCY1B1,INPP1,INSM1,ITGA7,ITPKA,L1CAM,LAMA2,STMN1,LMO2,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NTRK2,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE4B,ENPP2,PFKFB4,SERPINI1,PKD1,PLCB2,FXYD1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,QDPR,RGS4,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SH3BGR,SH3GL3,ABLIM3,BTBD3,EPN2,FAM214B,SMARCD3,SNAP25,SPP1,PEG10,TSPYL2,SST,SSTR2,STX1A,STXBP1,PLCB1,ARC,SYT1,SYT5,TRIM2,SYNE1,CDH22,THRA,KAT6B,TRO,TRPM2,UCHL1,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,SLC17A7,PCBP4" Computational M19344 MODULE_100 Genes in the cancer module 100. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.06E-38 8.61E-36 2.87E-36 2.09E-35 199 544 "ASIC1,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,APBA2,APLP1,FAM131A,APOC1,BCAS1,LGR5,ARHGDIG,PDE8B,ATP2B2,ALDH7A1,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,RHBDL1,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,CDH2,DCLK1,LARGE1,CACNA2D2,CHGB,CHN2,PLEKHB1,LHX2,STOML1,SULT4A1,CABP1,COL9A3,NRG2,CRMP1,CLIP3,CRYM,VCAN,CNTNAP2,ARHGEF4,RIMS2,GPRASP1,SNPH,RASSF2,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,SNAP91,PARD6A,SV2B,TMCC2,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,CELSR3,ENO2,RCAN2,NCALD,APC2,PTK2B,CHST15,OLFM1,FGFR1,FGFR3,FOLR2,RASL10A,KHDRBS3,CSPG5,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GATM,TUBGCP4,AHDC1,RUNDC3A,GNAO1,GNG4,STMN2,GRIA2,GRIK5,FAM107A,GUCY1B1,INPP1,INSM1,ITGA7,ITPKA,L1CAM,LAMA2,STMN1,LMO2,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NTRK2,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE4B,ENPP2,PFKFB4,SERPINI1,PKD1,FXYD1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,QDPR,RGS4,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SH3BGR,SH3GL3,ABLIM3,BTBD3,EPN2,FAM214B,SMARCD3,SNAP25,SPP1,PEG10,TSPYL2,SST,SSTR2,STX1A,STXBP1,PLCB1,ARC,SYT1,SYT5,TRIM2,SYNE1,CDH22,THRA,KAT6B,TRO,TRPM2,UCHL1,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,SLC17A7,PCBP4" Computational M2519 MODULE_137 CNS genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.97E-38 1.60E-35 4.00E-36 2.91E-35 199 546 "ASIC1,KDM5D,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,APBA2,APLP1,FAM131A,APOC1,BCAS1,LGR5,ARHGDIG,ATP2B2,ALDH7A1,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,RHBDL1,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,CDH2,DCLK1,LARGE1,CACNA2D2,CHGB,CHN2,PLEKHB1,LHX2,STOML1,SULT4A1,CABP1,COL9A3,NRG2,CRMP1,CLIP3,CRYM,VCAN,CNTNAP2,ARHGEF4,RIMS2,GPRASP1,SNPH,RASSF2,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,SNAP91,PARD6A,SV2B,TMCC2,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,CELSR3,ENO2,RCAN2,NCALD,APC2,PTK2B,CHST15,OLFM1,FGFR1,FGFR3,FOLR2,RASL10A,KHDRBS3,CSPG5,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GATM,TUBGCP4,AHDC1,RUNDC3A,GNAO1,GNG4,STMN2,GRIA2,GRIK5,FAM107A,GUCY1B1,INPP1,INSM1,ITGA7,ITPKA,L1CAM,LAMA2,STMN1,LMO2,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NTRK2,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE4B,ENPP2,PFKFB4,SERPINI1,PKD1,FXYD1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,QDPR,RGS4,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SH3BGR,SH3GL3,ABLIM3,BTBD3,EPN2,FAM214B,SMARCD3,SNAP25,SPP1,PEG10,TSPYL2,SST,SSTR2,STX1A,STXBP1,PLCB1,ARC,SYT1,SYT5,TRIM2,SYNE1,CDH22,THRA,KAT6B,TRO,TRPM2,UCHL1,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,SLC17A7,PCBP4" Computational M15252 GCM_MAPK10 Neighborhood of MAPK10 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.00E-11 3.25E-08 6.50E-09 4.73E-08 37 82 "NDRG2,APLP1,BBS2,CAMK2A,CAMK2G,DCLK1,PLEKHB1,FAM19A5,FAM171B,PREPL,CLIP3,SNAP91,DTNA,PLEKHA1,FGF1,GABBR1,FAM107A,KCNQ3,TTYH2,MBP,SCAMP5,TMOD2,SERPINI1,MAPK10,SCN2B,CNKSR2,BTBD3,FAM219A,NMNAT2,NFASC,LMO3,TACC1,FBXW11,SIK3,VSNL1,CLDND1,ANKS1B" Computational M18929 MODULE_12 Spinal cord (neuro-development) genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.69E-10 6.24E-07 1.04E-07 7.57E-07 97 360 "MTUS1,AGT,ALCAM,SRPX,BIN1,APBA2,APLP1,APOC1,BCAS1,SLC4A4,ALDH7A1,ATP6V0A1,DST,ST3GAL5,SGCE,MYRF,USP6,CDH2,DCLK1,SLIT2,CNN3,ARHGEF6,COL9A3,CRMP1,CLIP3,ARHGEF10,VCAN,ARHGEF4,RASSF2,DBN1,DNM1,DPP6,ECM2,EDNRB,ELN,ENO2,EPB41L2,CHST15,FCGRT,FGF1,FGFR1,FGFR3,PDLIM5,TRIM16,GABBR1,GATM,AHDC1,PCDH17,FERMT2,STMN2,GRIA2,FAM107A,VSIG4,ITGA7,L1CAM,MBP,NEFM,NNAT,NOVA1,SLC11A2,NTRK2,PALM,PAX6,PCDH9,CDK18,PDE4B,ENPP2,SERPINI1,PLEC,FXYD1,SCHIP1,KLK6,PTN,PTPN13,PTX3,QDPR,RNASE1,RTN1,S100B,SATB1,SH3GL3,SNAP25,SPP1,PEG10,TSPYL2,LMO3,ATP10B,SST,ZEB1,TRIM2,THRA,TPM1,TRO,UGT8,VSNL1,ZIC1,PCBP4" Computational M10191 GCM_MAP4K4 Neighborhood of MAP4K4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.02E-09 1.64E-06 2.08E-07 1.51E-06 56 171 "RALGAPA1,ABHD6,FMNL2,MTUS1,BBS2,MTMR2,CALM1,SPAG9,PLEKHB1,CLCN3,FAM19A5,MAP4K4,PREPL,SH2B1,CLIP3,PDE4DIP,DZIP3,PITPNC1,DTNA,GOLGA7,EPB41L2,APC2,ANKFY1,TJAP1,IL6ST,IPO5,TTYH2,SCAMP5,MYO9A,TMOD2,PSAT1,PTK2,PTPRD,RDX,CCDC92,SIRT2,CCDC88A,FAM219A,PDZD2,CLASP2,POGZ,ERBIN,FBXW11,ATMIN,TNS2,FRYL,SIK3,LRRC8A,WBP2,EIF4ENIF1,UBE2H,GORASP1,CLDND1,ANKS1B,SPIRE1,RTN4" Computational M3373 GNF2_DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.05E-09 1.67E-06 2.08E-07 1.51E-06 32 73 "AMPH,ATP2B2,ATP6V1G2,CAMK2A,CAMK2B,CHN1,SULT4A1,PREPL,CLIP3,SNAP91,SV2B,DNM1,RCAN2,NRN1,CORO2B,OLFM1,RUNDC3A,MAPT,TAGLN3,FXYD7,DIRAS2,SNAP25,FAIM2,NMNAT2,STXBP1,ARHGEF9,SYN1,SYT1,CAMTA1,VSNL1,NDRG4,SLC17A7" Computational M17046 GCM_PTK2 Neighborhood of PTK2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.94E-08 1.58E-05 1.75E-06 1.28E-05 48 145 "RALGAPA1,ABHD6,NDRG3,FMNL2,PKP4,BBS2,MTMR2,CAMK2G,LARGE1,PLEKHB1,CLCN3,FAM19A5,TMEM184B,MAP4K4,PREPL,DZIP3,GOLGA7,PLEKHA1,STAMBP,TJAP1,TTYH2,MGAT3,TMOD2,PTK2,PTPRD,CCDC82,CNKSR2,CCDC92,BTBD3,CCDC88A,USP33,FAM219A,TEX2,ARHGAP26,CLASP2,FBXW11,DOCK9,TNS2,FRYL,SIK3,WBP2,EIF4ENIF1,UBE2H,GORASP1,CLDND1,ANKS1B,SPIRE1,RTN4" Computational M13367 GNF2_TM4SF2 Neighborhood of TM4SF2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.03E-07 4.08E-04 4.08E-05 2.97E-04 15 26 "ATP2B2,CLIP3,SNAP91,SV2B,DNM1,HPCAL4,RUNDC3A,GNAO1,TAGLN3,DIRAS2,SNAP25,FAIM2,NMNAT2,STXBP1,SYN1" Computational M1706 GCM_SIRT2 Neighborhood of SIRT2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.39E-06 2.76E-03 2.51E-04 1.82E-03 19 43 "MTUS1,PLEKHB1,MAP4K4,PDE4DIP,PITPNC1,GOLGA7,TNK2,MRVI1,ANKFY1,GABBR1,IL6ST,SCAMP5,MYO9A,SIRT2,FAM219A,FBXW11,TNS2,GORASP1,RTN4" Computational M15601 GNF2_RAB3A Neighborhood of RAB3A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.81E-06 4.72E-03 3.71E-04 2.70E-03 17 37 "SULT4A1,SNAP91,SV2B,DNM1,DPP6,RCAN2,GABBR1,RUNDC3A,TAGLN3,FXYD7,NRCAM,FAIM2,STXBP1,ARHGEF9,SYN1,SYT1,NDRG4" Computational M2150 GCM_RAN Neighborhood of RAN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.94E-06 4.83E-03 3.71E-04 2.70E-03 53 197 "RALGAPA1,ABHD6,NDRG3,GPRASP2,ATP2B2,MTMR3,CALM1,SPAG9,LARGE1,CLCN3,FAM19A5,HECTD1,MAP4K4,IQCK,PREPL,SH2B1,CS,PITPNC1,GOLGA7,DCTN4,UBE2E3,FOXO3,JKAMP,STAMBP,USP19,PRRC2B,RBPJ,IPO5,MAP6,PPM1B,PTK2,UBR7,KLHL11,CCDC82,PNMA8A,CHD9,CCDC92,CCDC88A,USP33,FAM219A,CLASP2,POGZ,FBXW11,TNS2,SIK3,WBP2,EIF4ENIF1,GORASP1,TMEM237,SPIRE1,ZFAND5,RTN4,AAAS" Computational M8546 GNF2_MAPT Neighborhood of MAPT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.86E-06 5.57E-03 3.98E-04 2.90E-03 18 41 "ANK2,ADGRB3,CLIP3,SNAP91,SV2B,DNM1,DYNC1I1,RUNDC3A,GNAO1,GRIA2,MAPT,FXYD7,PALM,DIRAS2,RTN1,STXBP1,SYN1,SYT1" Computational M19545 GCM_DLG1 Neighborhood of DLG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.61E-06 7.80E-03 5.20E-04 3.79E-03 27 78 "ABHD6,ATP2B2,CAMK2G,PLEKHB1,FAM19A5,MAP4K4,PREPL,GOLGA7,PLEKHA1,STAMBP,IL6ST,IPO5,MAPK10,PTK2,CCDC25,CCDC92,BTBD3,FAM219A,ERBIN,FBXW11,TNS2,FRYL,SIK3,GORASP1,CLDND1,SH3GLB2,RTN4" Computational M19045 GCM_IL6ST Neighborhood of IL6ST MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.21E-05 9.86E-03 6.16E-04 4.49E-03 21 54 "ATP2B2,MAP4K4,SH2B1,GOLGA7,ANKFY1,IL6ST,IPO5,MYO9A,RDX,CCDC25,SIRT2,FAM219A,GLT8D1,ERBIN,TACC1,FBXW11,ATMIN,TNS2,GORASP1,CLDND1,RTN4" Computational M3543 GCM_NCAM1 Neighborhood of NCAM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.76E-05 2.24E-02 1.32E-03 9.58E-03 37 128 "RALGAPA1,IGDCC4,MTMR3,CALM1,PTBP2,SPAG9,CLCN3,IQCK,DMTF1,KMT5B,RASA4,DCTN4,ERBB4,CORO2B,UBE2E3,FOXO3,CELF1,DENND2A,AHDC1,USP19,KAT7,SMAP1,NFYA,NPTX1,CCDC82,PNMA8A,PPM1E,CLASP2,USP22,KAT6B,EIF4ENIF1,UBE2H,UBE3A,REEP1,TMEM237,SPIRE1,ZFAND5" Computational M10475 GCM_PTPRD Neighborhood of PTPRD MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.31E-05 3.50E-02 1.95E-03 1.42E-02 21 58 "RALGAPA1,ABHD6,NDRG3,PKP4,FAM19A5,MAP4K4,PREPL,PLEKHA1,TTYH2,PTK2,PTPRD,CCDC88A,FAM219A,CLASP2,FBXW11,DOCK9,FRYL,SIK3,UBE2H,ANKS1B,SPIRE1" Computational M10977 MODULE_563 Genes in the cancer module 563. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.05E-05 5.72E-02 3.01E-03 2.19E-02 9 15 "CADPS,SYNJ1,BAIAP3,COPB2,SNPH,GAD1,SNAP25,STX1A,SYN1" Computational M4874 MODULE_26 Genes in the cancer module 26. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.12E-04 9.08E-02 4.54E-03 3.31E-02 51 207 "FMNL2,GALNT13,ADORA1,BBOX1,APLP1,PDE8B,BMPR1B,ARHGEF25,DLGAP2,CFL2,CLOCK,HINFP,GDA,SPOCK3,CD99L2,DYNC1I1,SEZ6L2,DNAJC27,BAIAP2,FOXF2,AKAP3,CYP46A1,LINGO1,AGBL5,KCND1,KIFC3,PAXBP1,NTRK3,ZNF655,FA2H,PRPSAP2,ZDHHC4,PBRM1,LGI2,HSPA4L,OGDHL,FAIM2,SST,NSFL1C,TRIM2,PHF24,NSD1,SIK3,KHDC1,ACTR6,ZKSCAN5,TBC1D15,PRTFDC1,GAL3ST3,ACTR3B,CPNE4" Computational M4537 GCM_AQP4 Neighborhood of AQP4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.24E-04 1.01E-01 4.81E-03 3.50E-02 17 45 "NDRG2,FMNL2,AGT,PDE8B,SLC4A4,BBS2,QKI,LRIG1,PDE4DIP,DTNA,EPB41L2,ANKFY1,TTYH2,TMOD2,PSAT1,RDX,TACC1" Computational M19241 MODULE_181 Genes in the cancer module 181. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.52E-04 1.23E-01 5.60E-03 4.08E-02 69 306 "NDRG2,ADRA1D,SEMA7A,ATP6V1G2,RGS9,CFAP410,CALB2,HAP1,RHBDL1,CBLN1,CCK,CD86,ENTPD2,MAGI1,ASIC3,TAOK2,PPT2,AKAP7,NRG2,RIMS2,PPP6R2,FAM131B,KIAA0586,ZBTB24,MYEF2,FAM13A,SRPK3,NCALD,APC2,FLT1,AKAP3,RASL10A,PRELID3A,NSG1,RUNDC3A,CRCP,GNG4,GRIK5,GRM2,KCNN1,KCNQ3,L1CAM,SCAMP5,MSI1,TAGLN3,NNAT,PDE4A,PGAM2,JAKMIP1,PLIN1,PPP3CA,PSD,PTPRN,RAD51D,KCTD17,EXD2,ZC3H14,EMID1,SCN2B,FAM214B,SNAP25,SPART,SSTR2,SYT5,ADGRL3,THRA,TRPM2,SLC17A7,EPM2A" Computational M17233 MODULE_104 Genes in the cancer module 104. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.99E-04 1.62E-01 7.04E-03 5.12E-02 77 353 "NDRG2,ADRA1D,SEMA7A,ATP6V1G2,RGS9,CFAP410,CALB2,HAP1,RHBDL1,CBLN1,CCK,CD86,ENTPD2,MAGI1,ASIC3,TAOK2,PPT2,AKAP7,NRG2,RIMS2,PPP6R2,FAM131B,KIAA0586,ZBTB24,MYEF2,DNAH9,DTNB,FAM13A,SRPK3,NCALD,APC2,FLT1,AKAP3,RASL10A,PRELID3A,NSG1,RUNDC3A,CRCP,GNG4,DIDO1,GRIK5,GRM2,KCNN1,KCNQ3,L1CAM,MSI1,TAGLN3,NNAT,PAX6,PDE4A,PGAM2,JAKMIP1,PLIN1,C19orf57,PPP3CA,PSD,PTPRN,RAD51D,KCTD17,EXD2,ZC3H14,EMID1,SCN2B,FAM214B,INTS9,SNAP25,SPART,SSTR2,SYT5,ADGRL3,SZT2,THRA,PARD3,TRPM2,DNALI1,SLC17A7,EPM2A" Computational M1575 MODULE_207 Genes in the cancer module 207. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.16E-04 2.56E-01 1.07E-02 7.77E-02 53 226 "FMNL2,GALNT13,BBOX1,PDE8B,ARHGEF25,DLGAP2,CFL2,CLOCK,HINFP,GDA,CNTNAP2,SPOCK3,CD99L2,DYNC1I1,SEZ6L2,CDKL3,DNAJC27,FOXF2,AKAP3,DISC1,CYP46A1,CSDC2,LINGO1,AGBL5,KCND1,KIFC3,PAXBP1,MPP2,NTRK3,ZNF655,FA2H,LRRN3,PRPSAP2,PBRM1,LGI2,HSPA4L,OGDHL,FAIM2,PDZD2,SST,NSFL1C,PHF24,FAM189A1,NSD1,SIK3,KHDC1,ACTR6,ZKSCAN5,SMARCAD1,PRTFDC1,GAL3ST3,ACTR3B,CPNE4" Computational M10420 MODULE_274 Vesicular transport / synapse genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.56E-04 4.52E-01 1.81E-02 1.31E-01 24 82 "DOC2A,AMPH,CBLN1,CPNE6,DNM1,GABRB3,GABRG2,GAD1,GRIA2,GRM2,KCNK3,KCNN1,KCNQ3,KIF5A,NOVA1,NPTX1,SCN2B,SLC6A8,SNAP25,SST,SYN1,SYN2,SYT1,SYT5" Computational M12229 MODULE_381 Genes in the cancer module 381. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.06E-04 4.92E-01 1.89E-02 1.38E-01 7 12 "DOC2A,AMPH,PALM,SYN2,SYT1,SYT5,SLC30A3" Computational M5770 MODULE_63 Porins / transporters. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.61E-04 5.37E-01 1.99E-02 1.45E-01 49 211 "ASIC1,ADRB2,SHROOM2,AQP6,ASGR1,BMPR1B,CD86,CRLF1,CHRNA4,CNGA3,CNTFR,CSF2RA,CYBB,EPHB1,ERBB2,ERBB4,FCGR1A,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FOLR2,GABRB3,GABRG2,GFRA2,GHR,GPR75,LILRB4,LILRA2,IL6R,IL6ST,ITGAM,KCNH2,KCNK3,KCNQ3,KIT,LIFR,NTRK2,P2RX7,FXYD1,PTPRN,PTPRN2,PTPRO,SCN2B,SCN7A,TEK,TRPM2,GJC2" MicroRNA hsa-miR-466:mirSVR_highEffct hsa-miR-466:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.68E-163 3.74E-159 3.74E-159 3.44E-158 374 1924 "RALGAPA1,ACADM,NCKAP5,FMNL2,KLHL32,PLEKHH1,PWWP2A,ESYT2,BEND6,INTS2,MTUS1,RTL9,OSBPL8,ABCD2,ARHGAP20,PCDH10,FAM135A,AMPH,ANK2,PARG,EPB41L5,LGR5,IGDCC4,SLC4A4,STX16,ATP2A2,N4BP2L1,ATP6V1G2,ADGRB3,DST,SYNJ1,ARHGEF7,JAZF1,WASF1,CA8,CACNA2D1,THSD7A,SLC25A14,CLDN10,KRIT1,CDH2,LRRFIP1,CFL2,RCBTB2,SRSF11,SOCS6,MS4A7,B4GALT6,RAB28,QKI,TMEM184B,MAP4K4,FHL5,CNN3,CNR1,ARMC8,FAM149A,AKAP6,COL4A5,LETMD1,SLC4A8,ABI3BP,BAG4,MYRIP,CNRIP1,CPS1,CLOCK,OSBPL3,SIPA1L1,VCAN,PDE4DIP,PLXNA4,DZIP3,ERC2,CTH,PUM1,BOC,DOCK4,ARHGAP24,ZFYVE16,KIF26A,KCTD8,DAPK1,PABPC5,JAKMIP2,ZBTB24,MYEF2,KIAA0753,KLHL3,RHOBTB1,SNAP91,SACS,SPOCK3,SGSM2,DMD,NR1D2,CPEB2,DPP6,PDCD6IP,RCAN1,ARRDC4,DTNB,ECM2,GOLT1B,EBF1,FRY,PHF20L1,MBNL2,EGR3,EIF4G2,PLEKHA1,STARD3NL,PAN3,EIF1,RABEPK,SRRM1,DENND4A,ZNF549,ETV1,F5,CLVS1,ZNF461,ACSL4,SCML2,DLC1,GORAB,MED12L,POLK,MEX3B,FOXO3,SPECC1,UFM1,ERGIC3,CELF1,ST6GALNAC3,STAU2,DOT1L,MEGF11,GALC,ZNF274,ERAP1,GATM,IGSF5,WASHC2A,ADAM28,BRD8,SPIN1,TOX3,ZNF638,GNAO1,LNX1,ADGRA3,CCDC184,GPR37,ATP2B1-AS1,GRIA2,SOX21,PSIP1,GUCY1B1,FRMD3,ELOVL5,ZNF491,MSL1,ZNF181,ZIC5,TJAP1,SCIN,INPP5B,INSM1,SLC35G1,KIT,LAMP2,PAXBP1,HECTD2,NCOA7,SMAD9,MAPT,MARK1,TM6SF1,MEF2C,MEIS1,KITLG,AFDN,ZNF680,N6AMT1,MYO6,MYO9A,NCAM2,NEFH,NF1,VWA2,CNOT4,NPY,NOVA1,SLC11A2,NRCAM,SETD4,IGSF11,CHAMP1,OGG1,CLDN11,P2RX7,GPR137C,PCDH8,PCDH9,PRTG,PDE4B,OLA1,ABCB1,PKD1,XRN1,PLCL1,JAKMIP1,PCDH18,PMP22,STRN3,ING3,SH3KBP1,POLR2F,MINDY2,TATDN3,PPP2R5E,CEP41,PRKCB,MAPK9,DIRAS2,RELN,WBP1L,SNRK,CNTLN,PTCH1,PTPRD,C1orf109,MARCH1,CEP97,FAT4,FAM184A,NWD1,ZNF493,OXR1,KHDRBS2,ZDHHC14,RDX,ZMAT4,REV3L,RFX2,RFX3,RGS4,RGS12,SLC25A36,RIC8B,LGI2,TMLHE,ROBO1,RORB,PCMTD2,CCDC102B,NEK11,ATP8B4,LRRK2,ZNF568,RYR3,TRAPPC13,AP1AR,SAFB,SEMA6D,CSRNP3,ATXN2,TNFRSF19,SUPT20H,KIF27,TRA2B,SGK1,ZFP30,SH3GL3,ARX,FBXO11,FNDC3A,SYBU,SEC31A,NUBPL,SLA,PPP4R3A,BTBD3,CCDC88A,SLC12A2,SLC14A1,ATF7IP,ZFP1,SMARCD3,RCOR3,ANKRD36,MBD5,KIF13A,ZNF415,SNRPN,TMCC1,USP33,FAM219A,KDM3A,HECW1,SPP1,ITPRID2,SAMSN1,ERBIN,ELOVL4,SEPT8,RGL1,SULF2,NECAB1,RHBDL3,ARHGEF9,VPS13A,ADAMTS17,SYPL1,SYT1,COBL,ANKRD12,ADGRL3,AGTPBP1,TBCEL,KLHL4,SATB2,ZEB1,PCDHB10,SLC19A3,PCDHB7,PCDHB4,PUM2,GPRIN3,FRYL,SIK3,SIRT1,ACTR6,ASXL3,PDSS1,RUNDC3B,PPIL6,DCBLD1,ANKRD20A2,SSBP2,TTTY15,TUBB2A,UBE3A,UBTF,GORASP1,CCDC14,TBC1D15,VSNL1,ZNF781,RICTOR,XRCC4,PCDH20,ZFP37,ZBTB14,ZIC2,ZNF28,KCNT2,FSTL5,ZNF184,UPF3A,ZNF225,EVI5,RNF103,MPPE1,PARP11,AMN1,RTN4,JMJD1C,RNF170,KLHDC1,FXR1,IFT88,NETO1" MicroRNA hsa-miR-144:mirSVR_highEffct hsa-miR-144:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.06E-152 5.92E-149 2.96E-149 2.72E-148 368 1990 "ACADM,NCKAP5,NDRG3,CCDC85A,AXIN2,PWWP2A,ZNF608,WDR35,OSBPL8,TAOK1,SPARCL1,ALCAM,FAM135A,ANK2,APAF1,UPRT,BCAS1,LGR5,CDC14B,CADPS,MARCH3,ZSCAN18,NCOA1,NUMB,ATP2B2,ALDH7A1,ATP6V1G2,BACH1,MPDZ,NRP2,BMPR1B,DST,ARHGEF7,NAE1,JAZF1,CA8,CACNA2D1,CALB1,CALM1,CH25H,ISPD,RUNX1T1,PRC1,CCNH,USP6,C1orf52,CDH2,MAGI1,CFL2,COPB2,SOCS6,CHN2,B4GALT6,NDST3,LHX2,FBXO7,C4orf33,QKI,CNN3,CNR1,ARMC8,AKAP6,WHRN,COX4I1,MYRIP,ZFP28,CPS1,AKAP12,GDA,CSF1,OSBPL3,CSNK1G3,SOCS5,PHACTR3,PPP1R16B,CTH,PUM1,USP6NL,CYBB,DOCK4,HDAC9,LONRF1,TBC1D5,MATR3,KCTD8,ZBTB24,MYEF2,FBXL5,ZC3H11A,DDX46,RHOBTB1,SNAP91,SACS,ZNF582-AS1,DLX1,GRIN3A,DMD,USP3,CPEB2,RCAN1,ARRDC4,DTNA,EBF1,EDN1,ANKRD46,RASGRP1,FRY,MBNL2,GOLGA7,EIF4G2,IRAK4,RGS17,CALCRL,EPB41L2,LRRC17,RABEPK,STX2,SRRM1,ZNF585B,TMEM132C,ACSL4,DLC1,ST3GAL6,CEP78,MED12L,GTF2IRD2,FGF13,MAD2L2,POLK,SUCO,PCYOX1,SYNCRIP,ATP13A4,FLT1,PSD2,DCTN2,CAMKK2,ATP6V1H,KHDRBS3,ST6GALNAC3,MEGF10,RAPGEF6,KIAA1841,GCNT2,MSTN,AHDC1,GFRA2,PPARGC1A,GLI2,ZNF638,CBX1,LUZP2,GNAL,FERMT2,GPD2,LPAR4,PRDM5,COQ10A,PSIP1,FAM107A,RASSF8,UBE2QL1,ZHX1,FRMD3,MIER3,HMGCR,HSF2,ZNF181,SOWAHA,ZIC5,RBPJ,NME9,JAK2,SLC35G1,KCND2,CYP27C1,PAXBP1,HECTD2,NCOA7,SMAD1,SMAD9,MAP4,MARK1,MATN2,MBNL1,LRP1B,MEIS1,MEIS2,SRSF12,KITLG,PPM1L,MITF,MSR1,BEX5,NCF2,NF1,NFE2L2,ALDH1L2,NPTX1,IGSF11,LOC100128398,GPR137C,CNTN3,PRTG,PDE4A,SLC10A4,PFKFB2,PIK3C2A,PIK3R1,FAM218A,CCSER2,SNX10,FAM216A,PCDH18,MTRF1L,LRP12,SCHIP1,ING3,PPM1B,PPP2R5E,PRKACB,PKIA,MAPK4,EPDR1,MAPK9,GRAMD1C,DIRAS2,PRPSAP2,DCHS2,VPS13C,CNTLN,ELOVL2,TMEM260,PTPRG,C1orf109,PTX3,ZNF615,USP47,FAT4,FAM184A,RAP1GDS1,ENOX1,ZNF493,OXR1,RASGRF1,RBBP6,ZDHHC14,RET,SLC25A36,NUDT11,RNASEL,ZFHX4,CCDC82,ZNF532,SETD5,GSTCD,ROBO2,RPE,ZC3H14,TCP11L1,LRRK2,ZNF568,FAM192A,AP1AR,SALL1,SEMA6D,SMPD3,CASC3,FOXRED1,SUPT20H,RASA3,SGK1,FNDC3A,CNKSR2,SEC31A,ANKRD6,SEPHS1,CCDC88A,SLC12A2,LIMCH1,FAM126B,MYO16,PDZD2,BDP1,SP4,CAMTA2,ZNF302,SSTR2,NKAIN2,SS18,ST5,CEP68,RGL1,STXBP1,KLHL7,ZC3H4,VPS13A,ADAMTS17,PLCB1,ANKRD28,C12orf76,MCF2L,FBXW11,DMXL2,SATB2,ZEB1,RPGRIP1L,TCF12,CLASP1,NAT16,GPRIN3,TEK,FAM200B,SIRT1,ZFPM2,ITGB3BP,BHLHB9,TLR4,TMPO,TP53BP2,RGMB,SYNPO2,TRIO,STXBP4,DCBLD1,TSN,ANKRD20A2,SGK3,TUBB1,RPL7L1,PLEKHH2,RICTOR,GUSBP1,PCDH20,ZFP37,ZBTB14,ZIC1,KCNT2,ZNF540,ZBTB38,TMEM237,ZSCAN26,DPYSL5,SPIRE1,ZNF225,MFF,CADM2,STOX2,RNF103,ADAMTS9,CIAPIN1,NAV3,WNK3,FAM13C,AMN1,FZD3,DOCK8,RTN4,KAT6A,PHTF2,JMJD1C,NLRP3,RNF170,FRMD6,IFT88,NETO2,GAN,SENP7" MicroRNA hsa-miR-3074:mirSVR_lowEffct hsa-miR-3074:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.91E-148 3.31E-144 1.10E-144 1.01E-143 354 1897 "KCNH8,SYS1,ACTN1,XKR4,CCDC85A,PTCHD1,INTS2,PCDH19,TBC1D14,WDR35,CC2D2A,SMIM17,ALCAM,FAM135A,GPRASP2,AMPD2,OGT,DPP10,EP400,C6orf89,CCDC146,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APC,EPB41L5,UPRT,DDO,USP37,PPP4R4,ZFYVE28,DOCK11,BBS2,KSR1,DST,NAE1,WASF1,CACNA1B,CACNB4,VXN,CAST,ISPD,SPAG9,RUNX1T1,PRC1,LDB2,USP6,LRRFIP1,COPB2,NDST3,RAB28,NRXN3,CLCN3,TPP1,ABCG2,CNN3,CNTN1,AKAP7,ARMC8,COL4A5,COL9A3,AKAP5,SLC4A8,MYRIP,ZNF521,CNRIP1,SLC35F1,GDA,SNCAIP,LRIG1,OSBPL3,PDE4DIP,PLXNA4,GREB1,RIMS2,ZSCAN23,RUBCN,CCDC144A,KIAA0408,BOC,DOCK4,GPRASP1,MYADM,MATR3,KIAA0586,KCTD8,DAPK1,PITPNC1,TIAM2,KLHL3,ZC3H11A,DDX46,PLPPR4,SNAP91,SV2B,WDR20,CPEB2,PDCD6IP,GOLT1B,EBF1,EDNRA,SEMA3D,KLHL5,CELSR3,PHF20L1,AASS,TMEM35A,PAN3,VPS13B,EPB41,EPB41L2,EPHB1,RABEPK,ETV1,RRAGB,SIRPB1,KATNAL1,EYA1,NSRP1,FAM198B,RPS6KC1,ZSCAN30,SEC24B,FGF13,POLK,MEX3B,SYNCRIP,RGPD5,FLT1,EFCAB2,NBEA,SPECC1,UFM1,FAM49B,TPK1,CAMKK2,CELF1,NSG1,HRASLS5,GABRG2,TRAF3IP2,GALC,ZNF559,DISC1,GATM,IGSF5,NFU1,GGT5,LYVE1,GLUL,HTATSF1,RAB40B,FERMT2,WDFY3-AS2,LILRB4,GPD2,PCLO,GSTM5,BVES,FAM107A,GUCY1B1,MUM1,HAS2,MIER3,AGBL5,HNF4G,AGFG1,ZNF546,IGF1,TJAP1,SCIN,INSM1,ITGAM,KIF5A,IPO5,STXBP5,KTN1,PAXBP1,HECTD2,NCOA7,SMAD1,PIK3AP1,MATN2,MEIS1,KCTD6,KITLG,PPM1L,AFF1,MMP16,MN1,PTOV1,MYCN,NCAM2,NOVA1,DNHD1,NPR2,SMIM11A,NTRK2,OCRL,CHAMP1,GPR137C,GLIPR1L2,PCDH9,PDE3A,ENPP2,GPR85,NLGN3,SERPINI1,NALCN,PIK3R1,ZNF655,SNX10,RETREG1,TMEM38A,FAM216A,PLCL1,PDZRN4,MAPKAP1,MAGEL2,DRAM2,MINDY2,PRKCB,GRAMD1C,DCHS2,CNTLN,ZSCAN32,PTPRG,PPP2R3C,FAM184A,RAP1GDS1,ENOX1,OXR1,KHDRBS2,GTDC1,NUDT11,PBRM1,RNASEL,CCDC82,SETD5,ALG9,KIRREL1,RORB,PCMTD2,RPE,MCMBP,ATP8B4,TCP11L1,STK32B,ABCA11P,CCDC112,SEMA6D,ATXN2,FNIP1,SEC14L1,SCAF8,SGK1,KIF21A,ARX,SHC4,FNDC3A,CNKSR2,NLGN1,ANKRD6,WDR37,PREX2,EPN2,KANSL3,CCDC88A,SLC12A2,SLC14A1,SLC22A4,MYH15,ANKRD36,LIMCH1,SNAP25,SNCA,MBD5,SNRPN,MYO16,USP33,DOP1A,PDZD2,BDP1,FNBP1,SOX11,HECW1,UHRF1BP1L,MYCBP2,ITPRID2,SS18,NXT2,SEPT8,RGL1,ADHFE1,KANK1,KLHL7,SYNE2,VPS13A,SYN2,ANKRD28,ANKRD12,FAM208A,ADGRL3,AGTPBP1,FBXW11,DMXL2,CLASP1,PCDHB4,PUM2,USP32P1,SIK3,FAM200B,PMS2CL,ARL10,BEX4,CSMD1,TPM1,RGMB,SYNPO2,METTL3,SMUG1,RUNDC3B,TRPS1,TTC3,UBE3A,UGT8,FLRT2,VLDLR,WRN,GUSBP1,ZIC1,MICU3,KCNT2,ZBTB38,REEP1,POLR3H,SMARCAD1,DHX33,EMSY,SLC38A1,EVI5,TMEM178A,HPS4,FIP1L1,FAM47E,WNK3,PDSS2,EPM2A,FAM13C,FZD3,DOCK8,RTN4,FRMD6,NETO2" MicroRNA hsa-miR-582-5p:mirSVR_highEffct hsa-miR-582-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-146 5.87E-143 1.47E-143 1.35E-142 348 1847 "NDRG2,AXIN2,AP2A2,KLHL13,KCTD16,OSBPL8,ALCAM,PCDH10,FAM135A,MAP4K3,APC,UPRT,BCAS1,LGR5,TMEFF1,ZBTB10,RASL11B,EIF4G3,N4BP2L1,DPY19L3,BMPR1B,NAE1,IL33,KALRN,PTBP2,SLC25A14,CAST,CH25H,SPAG9,RUNX1T1,USP6,DGKI,CDH2,ZMYM4,MAGI1,CDO1,CCPG1,CFL2,SRSF11,CHN2,CNOT8,NDST3,PLAA,PPT2,C4orf33,CNN3,CNR1,AKAP6,COL9A1,SLC4A8,ABI3BP,RCHY1,COX4I1,FAM171B,PREPL,CREM,ANKRD44,GDA,CS,VCAN,SOCS5,DZIP3,CTH,GREB1,PUM1,USP6NL,DOCK4,ZFYVE16,LIN54,KIAA0586,MAML1,DGKG,DAPK1,PABPC5,BRINP1,ZNF804A,ZC3H11A,GSDME,PLPPR4,SNAP91,SV2B,SPOCK3,GRIN3A,DMD,NR1D2,DPP6,ACOT8,DTNA,DNAJB6,GOLT1B,E2F5,EDNRA,RASGRP1,FRY,YAF2,PHF20L1,APH1A,KMT5B,EIF4G2,PLEKHA1,EPB41L2,SRRM1,MRPL37,ETV1,ADGRV1,CLVS1,NSRP1,ZNF461,ACSL4,SCML2,GORAB,MED12L,FGF12,POLK,SUCO,MEX3B,SYNCRIP,RGPD5,FLT1,COQ5,HVCN1,STAMBP,ATP6V1H,STAU2,ABLIM2,OGA,FYB1,CHL1,IQGAP2,ZNF559,GATM,SULT1C4,CYP46A1,HPGDS,GLI2,MSL3,MAP7D2,GNAL,GNAO1,FERMT2,ADGRA3,LPAR4,GPR34,GRIA2,PRDM5,RNF165,AP4S1,SOX21,PSIP1,GUCY1B1,ARHGAP36,ELOVL5,HMGCR,HNF4G,ZDHHC15,NEGR1,ZIC5,RBPJ,INPP5B,INSM1,PAXBP1,NCOA7,SMAD1,PIK3AP1,MAP2,MAP6,MARK1,MEIS1,MIA2,POC1B,MITF,MMP16,ZNF680,NRBP2,MYO6,MYO9A,NF1,NFE2L2,NOVA1,GPR137C,GLIPR1L2,PCSK1,PCSK5,PRTG,PDE4A,GPR85,NALCN,PIK3C2A,ZNF655,FAM218A,CCSER2,SNX10,RETREG1,XRN1,MTRF1L,TRHDE,STRN3,LRP12,SCHIP1,EPB41L4B,SH3KBP1,PRKACB,CEP41,MAPK9,MAPK10,GRAMD1C,HYDIN,MASP1,RELN,CNNM2,CNTLN,BDNF-AS,MTMR10,PTK2,EML5,CEP97,TMEM255A,FAT4,FAM184A,NWD1,RASGRF1,RBBP6,KHDRBS2,REV3L,GTDC1,SLC25A36,NUDT11,PBRM1,ZFHX4,ZNF532,KLHDC8A,CARF,ROBO2,SPIN3,ATP8B4,MAP6D1,LRRK2,ABCA11P,NCBP3,SEMA6D,LRFN5,FOXRED1,ZFP30,SH3GL3,ARX,AMBRA1,FBXO11,R3HDM2,CNKSR2,WDR37,FAM81A,BTBD3,SLC6A8,ARHGEF40,SLC12A2,GKAP1,SMARCA4,CDK5RAP2,LIMCH1,SNAP25,KIF13A,ZNF415,SNRPN,MYO16,TRERF1,BDP1,KDM3A,GLT8D1,ZNF423,TSPYL2,SPART,CLASP2,TROVE2,CAMTA2,MESP1,SST,ZC4H2,LARP4,SS18,ERBIN,SEPT8,DIP2A,ADHFE1,SULF2,ZC3H4,SYNE2,NUDT10,PLCB1,SYPL1,C12orf76,ANKRD12,TAF9,FAM208A,ADGRL3,AGTPBP1,TCF4,TCF12,SYNE1,PUM2,USP32P1,FRYL,DICER1,SIRT1,SLC44A1,ACTR6,RIMBP2,CSMD1,KAT6B,NPL,TRIO,TSN,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE3A,UGT8,ZNF709,P2RY12,ZNF781,WRN,CLDND1,RICTOR,PCDH20,ZIC1,KCNT2,TRIM9,ZNF540,FTSJ1,EMSY,ADAMTS9,NAV3,KCNAB1,FAM47E,DNAH10,FAM13C,FZD3,RTN4,HNRNPA3,PHTF2,FBXO36,CASC15,ADAMTSL3,JMJD1C,TRAM2-AS1,FRMD6,NETO1,FAM198A" MicroRNA hsa-miR-30e:mirSVR_highEffct hsa-miR-30e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.62E-145 2.03E-141 4.05E-142 3.73E-141 359 1991 "RALGAPA1,CLK4,ABHD6,GALNT16,GALNT13,RNF157,ADD1,BRAP,KIAA1211,LRFN2,ADRB2,AP2A1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,VAT1L,USP37,PPP4R4,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B2,DPY19L3,ADGRB3,MPDZ,SEC11C,NRP2,BID,KSR1,DST,MTMR2,CALB2,CABP7,SLC25A14,CARS,RUNX1T1,CBS,USP2,SYNGR3,DGKI,SEPT7,ZBED1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,NDST3,NRXN3,FAM189A2,QKI,MAP4K4,ARHGEF6,CNR1,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ZNF521,ZFP28,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PHACTR3,PHF14,GREB1,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TBC1D5,MATR3,KCTD8,MAML1,YTHDC1,JAKMIP2,ALKBH8,PLPPR4,SACS,SPOCK3,WDR20,RAB39B,DMD,CPEB2,DMTF1,SLC12A6,PDCD6IP,DTNB,MAMLD1,DNM1L,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,DCTN4,EPB41,EPB41L2,LRRC17,STX2,DENND4A,EXTL2,ABCA8,SH3YL1,SCML2,GORAB,POLR1B,AMOTL2,PRKAG2,POLK,SCARA3,UBE2E3,MEX3B,SYNCRIP,RGPD5,DCTN2,SMC2,UFM1,FAM49B,ATP6V1H,KHDRBS3,NSG1,MSANTD4,AP4B1,OGA,ZMAT1,CHL1,TRAF3IP2,IP6K3,ERAP1,KIAA1841,GATM,GCNT2,SULT1C4,PCDH17,PPARGC1A,MALT1,TTBK1,DBF4,TNRC6A,GNAO1,ADGRA3,PRUNE2,TDRKH,GPR12,GRB10,GRIA2,CIT,FAM19A2,GUCY1B1,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,NEGR1,SMAP1,C2orf72,SOWAHA,ZNF678,FAM69A,LRRTM1,STXBP5,LAMP2,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,MBD1,MBP,CHIC1,MEIS1,MEIS2,MID1,PPM1L,MITF,ADAM22,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,ZNF827,PCDH9,PDE4D,GPR85,OLA1,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,TMEM260,PTPN13,PPP2R3C,USP47,OXR1,REV3L,PRRT2,ERI2,FIGN,ZFHX4,SETD5,EXD2,CARF,GSTCD,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN8A,SUPT20H,FRMPD1,ARX,KIF16B,CPEB3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,FAM81A,KANSL3,PKNOX2,TET1,ZFP1,RCOR3,TTC17,ANKRD36,LIMCH1,SNRPN,TMCC1,MYO16,BDP1,DOK5,KDM3A,SP4,HECW1,RBM26,SPART,CLASP2,SSTR1,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,NEK4,RGL1,ADHFE1,STXBP1,SYPL1,COBL,CAMTA1,MCF2L,ADGRL3,DMXL2,SATB2,USP22,CLASP1,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,AP4E1,SLC44A1,ACTR6,R3HDM1,CSMD1,TP53BP2,TPM1,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,DCBLD1,ANKRD20A2,SSBP2,RPL7L1,PLEKHH2,CCDC14,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,ZNF23,MICU3,AGMO,MKRN3,CELF4,ZBTB38,SPIRE1,ZFAND5,SLC30A4,MAP3K12,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,SMIM8,HNRNPA3,PHTF2,CASC15,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-410:mirSVR_highEffct hsa-miR-410:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.11E-144 1.18E-140 1.97E-141 1.81E-140 340 1789 "RALGAPA1,KCNH8,NCKAP5,ACTN1,FMNL2,CCDC85A,ADCY8,AXIN2,UNC5A,PWWP2A,ADRA1B,ZNF608,WDR35,TXNDC16,ADGRF5,C1QTNF3,ABCD2,GPRASP2,AMPH,LCORL,MAP4K3,PARG,UPRT,VAT1L,TNRC6C,CASK,NUMB,TMEM108,RNF182,DPY19L3,ADGRB3,SEC11C,NRP2,BMPR1B,SYNJ2,BTK,JAZF1,C5,CA8,CALB1,KALRN,PTBP2,SLC25A14,RUNX1T1,ARHGEF25,CLDN10,CD86,SYNGR3,CDH2,LRRFIP1,MAGI1,NOG,SRSF11,CHN2,NDST3,NRXN3,CLTC,FAM19A5,QKI,CNN3,ARMC8,FAM149A,AKAP6,COL4A5,COL9A1,COL9A3,AHCTF1,RTTN,MYRIP,HAPLN1,TRIM69,SNCAIP,OSBPL3,CSNK1G3,SUSD5,SOCS5,PHACTR3,PNPLA8,CTH,ZSCAN23,CCDC144A,BOC,ARHGAP24,HDAC4,MATR3,DAPK1,IP6K1,PABPC5,MYEF2,ZC3H11A,RHOBTB1,SACS,FAM107B,DMD,DYNC1I1,DPYSL2,DTNA,DNM1L,E2F6,AASDH,EDNRA,KLHL5,OPTN,YAF2,FAM13A,PHF20L1,GOLGA7,PLEKHA1,TMEM35A,RABEPK,SRRM1,DENND4A,ETV1,RPS6KC1,TUBB3,CEP78,FGF12,FGFR1,MEX3B,SYNCRIP,SEMA4D,FOLH1,UFM1,TPK1,ATP6V1H,ST6GALNAC3,STAU2,MSANTD4,MPP6,FYB1,GALC,ZNF234,ZNF274,ZNF559,DISC1,KIAA1841,MSTN,ARFIP1,GDF9,PCDH17,MALT1,COPS8,RAB30,ZNF638,LUZP2,FERMT2,ADGRA3,TDRKH,STON1,GRIA2,BTN2A1,FAM19A2,RABL2A,PSIP1,MAP4K5,HAS2,GABARAPL2,HNMT,ZNF491,MSL1,SOWAHA,NKD1,ZIC5,IL12A,INSM1,ITPKB,KCNN2,STXBP5,TTYH2,LAMP2,HECTD2,NCOA7,SMAD1,MARK1,MAT2A,MATN3,TM6SF1,LRP1B,SRSF12,SCAMP5,MKLN1,MN1,MSR1,MYO9A,MYT1,NF1,NFE2L2,NPY,NPTX2,SLC11A2,NTRK2,OCRL,CLDN11,CNTN3,PCDH8,PCSK5,PDE3A,NALCN,CCSER2,PLCL1,EPB41L4B,PPM1B,PPP3CA,MAPK9,HYDIN,DIRAS2,MASP1,SNRK,PIGG,CNTLN,PTCH1,MTMR10,PTPRG,C1orf109,PTX3,PEX2,RAD17,RAP1GDS1,ENOX1,RBBP6,RDX,RFX3,PBRM1,CCDC82,ZNF532,TMLHE,CARF,RORB,MCMBP,SGSM1,LRRK2,KCNIP3,RMI1,TNFRSF19,ZFP2,SUPT20H,HSPA4L,FERMT1,CPEB3,CHD9,CCDC92,NLGN1,ANKRD6,PPP4R3A,ARHGEF40,SLC14A1,CPEB4,MBD5,CABCOCO1,ANKFN1,SNRPN,USP33,PDZD2,TRERF1,BDP1,SP4,NMNAT2,UHRF1BP1L,KDM4C,SPART,TROVE2,SAMSN1,SSTR1,LARP4,TTBK2,SULF2,SYN2,SYPL1,SYT1,COBL,ANKRD12,CAMTA1,ADGRL3,FBXW11,TCF4,SATB2,TRIM2,RPGRIP1L,TCF12,PCDHGB7,SYNE1,DOCK9,GPRIN3,SLC35G2,FRYL,HIF3A,CCDC173,SIK3,FAM200B,DICER1,SIRT1,ITGB3BP,CDH22,SLC44A1,TIAM1,BHLHB9,ERCC6L2,BEX4,CSMD1,TPM1,NPL,RGMB,SYNPO2,PDSS1,STXBP4,ANKRD20A2,TUBB1,ZNF610,UBTF,PLEKHH2,USP1,BCL2L13,VSNL1,GUSBP1,SLC47A2,PCDH20,ZFP37,ZNF17,MICU3,TRIM9,AGMO,MKRN3,LYPD6,TCEAL7,REEP1,SMARCAD1,MAP3K12,ADAMTS9,PPP1R3F,FIP1L1,PDSS2,RTN4,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,TTC7A,KLHDC1,FRMD6,NETO1" MicroRNA hsa-miR-200c:mirSVR_highEffct hsa-miR-200c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.54E-144 1.42E-140 2.03E-141 1.87E-140 342 1812 "RALGAPA1,KCNH8,ACHE,CLK4,SYS1,XKR4,PWWP2A,PTCHD1,SLC24A4,MTUS1,CC2D2A,HFM1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,LCORL,MAP4K3,PKP4,PARG,VAT1L,SHROOM2,CDC14B,IGDCC4,NUMB,STX16,ATP2A2,DPY19L3,ADGRB3,MPDZ,PROM1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,IL33,CA8,CACNB4,THSD7A,PTBP2,CAST,SPAG9,ZMYM4,NOG,CFL2,COPB2,CHN2,FAM19A5,QKI,CNN3,CNTFR,AKAP7,SLC4A8,GAL3ST1,BAG4,HINFP,GDA,CS,CSF1,SEC24C,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,USP6NL,CCDC144A,CYBB,DOCK4,GPRASP1,ARHGAP24,DCAF8,LIN54,MATR3,KCTD8,TMEM170A,GIT2,ELMSAN1,MYEF2,RUSC2,PLPPR4,WDR20,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DYNC1I1,DTNA,MAMLD1,DNAJB6,DNM1L,CNNM1,TMTC1,FSD1L,YAF2,EGR3,GOLGA7,EIF4G2,PAN3,MTSS1L,EXTL2,ACSL4,TAOK3,DLC1,FER,POLR1B,FGF12,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXF2,ATP13A4,ANKFY1,NOP56,JKAMP,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,AP4B1,OGA,FYN,ZNF274,SIGLEC8,KIAA1841,GATM,MSTN,SESN1,FREM1,MALT1,COPS8,TNRC6A,FERMT2,GRB10,GRIA2,FAM19A2,PSIP1,MAP4K5,RASSF8,MIER3,HLF,NEGR1,AGFG1,ZNF181,TJAP1,IL12A,KCND2,KCNJ16,KIF2A,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LRP1B,MEST,MITF,MYCN,CNOT4,NOVA1,NPTX1,SMIM11A,NTRK2,NUCB2,IGSF11,CHAMP1,P2RY1,PCDH8,PRTG,PDE4B,GPR85,GNG2,PFKFB2,SERPINI1,NALCN,FAM218A,SNX10,XRN1,KCTD15,PLCL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SNRK,CNTLN,PTCH1,BDNF-AS,MTMR10,TMEM260,PTPN13,PTPRD,EML5,ZSCAN2,FAT4,OXR1,RADX,MSANTD2,RDX,RET,REV3L,ERI2,GTDC1,FIGN,NUDT11,RNASEL,CCDC82,ZNF532,CARF,ROBO1,ROBO2,RORB,CCDC102B,ARMH4,FBXW7,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,SEMA6D,SCN8A,SCP2,SUPT20H,KIF21A,SHC4,AMBRA1,FNDC3A,R3HDM2,SEC31A,ANKRD6,FAM81A,KDM4D,SLC12A2,SLC14A1,ZNF667,MAST1,MYH15,SNAP25,MBD5,KIF13A,SNRPN,TMCC1,FAM219A,PDZD2,BDP1,DOK5,KDM3A,KDM4C,ZNF423,SPART,CLASP2,TROVE2,ITPRID2,ZNF302,SS18,MPRIP,SEPT8,RGL1,PHLDB1,KANK1,SYNE2,ARHGEF9,VPS13A,SYT1,ANKRD28,ADGRL3,SATB2,ZEB1,CLASP1,PUM2,SLC35G2,FRYL,CCDC173,RNF216P1,TEK,ZFPM2,ERCC6L2,CSMD1,TRIO,RUNDC3B,AMACR,TUBB2A,FAM155A,UGT8,VLDLR,TBC1D15,VSNL1,RBFOX3,WIPF1,CLIP2,CLDND1,GUSBP1,XRCC4,TRIM9,MKRN3,LYPD6,TCEAL7,ZBTB38,REEP1,TFIP11,SMARCAD1,EMSY,EVI5,TMEM178A,CIAPIN1,NAV3,FAM13C,KAT6A,PHTF2,NLRP3,RNF170,KLHDC1,FXR1,IFT88,GAN" MicroRNA hsa-miR-2053:mirSVR_highEffct hsa-miR-2053:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-143 5.80E-140 7.25E-141 6.67E-140 353 1943 "RALGAPA1,FMNL2,KLHL32,CCDC85A,TMCC3,PWWP2A,ESYT2,PTCHD1,BEND6,DPY19L2P4,WDR35,C1QTNF3,PCDH10,FAM135A,DPP10,LRCH2,SEMA7A,LCORL,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,DDO,LGR5,CDC14B,CASK,LINC00173,CDK13,ASPA,ZBTB10,NCOA1,SLC4A4,STX16,RNF182,DPY19L3,MPDZ,SYNJ1,SYNJ2,FUBP1,NAE1,IL33,CACNB4,THSD7A,CALM1,PTBP2,RUNX1T1,NFS1,PRC1,CLDN10,RGN,C1orf52,L3MBTL4,CCPG1,NUMBL,RCBTB2,SRSF11,CHGB,B4GALT6,PLAA,ABCG2,FAM19A5,C4orf33,CNGA3,CNR1,AKAP7,AKAP6,COL4A5,SLC4A8,ABI3BP,RTTN,ZFP28,CLOCK,PREPL,HINFP,ANKRD44,CLIP3,CS,ARHGEF10,CSNK1G3,DZIP3,PNPLA8,PUM1,CYBB,DOCK4,HDAC9,GAPVD1,RIPOR2,ZFYVE16,DGKB,PABPC5,JAKMIP2,ZBTB24,FBXL5,KLHL3,ZC3H11A,GSDME,SV2B,SPOCK3,SGSM2,RAB39B,DMD,DNM1,DOCK2,SLC12A6,DTNA,ECM2,DNAJB6,DNM1L,E2F5,EDNRA,EDNRB,HIPK3,RASGRP1,SEMA3D,TMTC1,FSD1L,PHF20L1,MBNL2,GOLGA7,IRAK4,PLEKHA1,MRNIP,STARD3NL,CALCRL,PAN3,RCAN2,GPHN,SRRM1,DENND4A,NCALD,CEP85L,SIRPB1,CLVS1,ZNF461,ACSL4,CEP78,ZSCAN30,GORAB,FER,FGFR3,FHL1,POLK,JKAMP,SMC2,UFM1,PDLIM5,USP21,ATP2C1,ERGIC3,CELF1,ST6GALNAC3,STAU2,HRASLS5,CHL1,ZNF274,ERAP1,DISC1,SULT1C4,MSTN,ADAM28,PPARGC1A,MALT1,LYVE1,DHRS4,GLYR1,LUZP2,STON1,LPAR4,PCLO,CNTRL,GRIA2,FAM19A2,BVES,PSIP1,GUCY1B1,IRAK3,ZHX1,MIER3,ELOVL5,GABARAPL2,ICA1,IDH3A,FAM69A,NME9,SLC35G1,KCND2,KTN1,LAMP2,LIG4,HECTD2,GPR155,MAP2,MARK1,MBD1,MBNL1,LRP1B,MEF2C,MEST,POC1B,MMP16,MSR1,MYO9A,NFE2L2,ALDH1L2,CNOT4,NOVA1,PCBP3,SLC11A2,NTRK2,SETD4,OGG1,ETFRF1,PCDH9,PCSK5,PDE4B,PDE4D,SERPINI1,FAM218A,RETREG1,GPSM2,PLCL1,PCDH18,PMP22,TRHDE,SCHIP1,ING3,PILRA,PPP2R2B,PPP2R5E,PPP3CA,RANBP3L,MAPK4,HYDIN,SAMD9,VPS13C,PIGG,CNTLN,MTMR10,PTPRB,PTPRO,PPP2R3C,TMEM255A,RAD51D,FAM66C,ZNF793,FAT4,SUSD4,ZNF493,RADX,KHDRBS2,RDX,GTDC1,RNASE1,ZNF532,CARF,CCDC102B,BAALC,GLDN,LRRK2,PTGR2,ABCA11P,CLIP1,TRAPPC13,LRFN5,FNIP1,SGK1,CHD9,FHOD3,NLGN1,PPP4R3A,BTBD3,EPN2,SEPHS1,SLC12A2,SLC22A4,CPEB4,ZFP1,ZNF667,SNCA,LMBRD1,SNRPN,PDZRN3,TRERF1,SP2,HECW1,UHRF1BP1L,SPP1,ZC3H13,RBM26,PBLD,CLASP2,SAMSN1,LARP4,NKAIN2,SS18,KLHL7,PRRC2C,VPS13A,PJA1,EXOC7,FAM208A,ADGRL3,TBCEL,FBXW11,KLHL4,SATB2,CUX2,ZEB1,SZT2,SYNE1,PCDHB4,PUM2,SIK3,ZNF34,SLC44A1,TIAM1,TLR4,CSMD1,RGMB,SYNPO2,STXBP4,DCBLD1,ANKRD20A2,TTC3,SGK3,PLEKHH2,TOM1L2,WNT7A,ZNF711,MICU3,ZNF540,TCEAL7,FSTL5,ZNF184,SPIRE1,SMARCAD1,ZNF225,MFF,DNALI1,EVI5,PRDM10,SEMA3B,NAV3,PPP1R3F,PLSCR4,PDSS2,FAM13C,KAT6A,PHTF2,ADAMTSL3,TIGD6,NETO1,GAN,SENP7" MicroRNA hsa-miR-493*:mirSVR_highEffct hsa-miR-493*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-143 6.68E-140 7.42E-141 6.84E-140 350 1910 "CLK4,NCKAP5,FMNL2,TMEM132B,GALNT13,UNC5A,BEND6,SLC24A4,ZNF608,KLHL13,PCDH19,RTL9,OSBPL6,WDR35,OSBPL8,SPARCL1,ALCAM,SRPX,ABCD2,FAM135A,ANK2,LCORL,MAP4K3,PHF12,USP37,MADD,TMEFF1,ARNTL,CADPS,ZBTB10,NCOA1,RASL11B,ATP1B3,ATP2A2,BCL7A,NRP2,BLM,DST,ARHGEF7,FUBP1,CALM1,KALRN,PTBP2,USP6,USP2,DGKI,CDH2,LRRFIP1,LOC730101,CLGN,SRSF11,SOCS6,B4GALT6,NDST3,NRXN3,PLAA,CNN3,IQCK,AKAP6,COL9A3,AHCTF1,RTTN,TOGARAM2,ZNF521,CLOCK,GDA,LRIG1,PDE4DIP,FAM169A,ERC2,KIAA0408,BOC,ZFYVE16,KCTD8,PABPC5,BRINP1,ELMSAN1,ZNF804A,HEPH,DDX46,SNAP91,SACS,GRIN3A,RAB39B,NR1D2,CDON,ECM2,EDIL3,EDNRB,HIPK3,FCF1,RASGRP1,FRY,FAM13A,PHF20L1,MBNL2,TENM1,RGS17,GPHN,DENND4A,EXTL2,EYA1,ABCA8,ACSL4,TAOK3,SCML2,FCGR1A,SEC24B,POLK,PSD2,SLC37A3,C2orf88,NBEA,HVCN1,TPK1,ATP6V1H,ATP2C1,STAU2,ABLIM2,MEGF11,GALNT15,GABRG2,TRAF3IP2,GAD1,RAPGEF6,ZNF234,DISC1,LRRC37A6P,CPLX2,GATM,MSTN,ARFIP1,AHDC1,ADAM28,GFRA2,PPARGC1A,MALT1,ZNF276,RNPS1,HPGDS,TNRC6A,KDM2B,FERMT2,PRUNE2,STON1,ATP2B1-AS1,DIDO1,AP4S1,MIER3,HMGCR,ZNF491,TCEAL6,SMAP1,IFI16,ZNF181,MYLK2,LRRCC1,ITGAM,ITPKB,SLC35G1,KIF5A,KIT,STXBP5,L1CAM,LAMA2,LAMP2,LIG4,PAXBP1,HECTD2,NCOA7,SMAD1,MAP4,MAP6,TM6SF1,MEF2C,MGAT3,POC1B,AFDN,GIT1,MSR1,ZC3H12B,NELL2,NF1,NOVA1,LOC100128398,GPR137C,PCDH9,PCSK5,CDK18,PDE4D,GNG2,OLA1,NLGN3,PIK3C2A,PIK3R1,XRN1,FAM216A,PCDH18,SMIM7,PURG,PDZRN4,PMP22,TRHDE,MAPKAP1,LRP12,SCHIP1,ING3,MINDY2,PPP2R2C,LRRN3,PPP2R5E,PPP3CA,PKIA,GDPD1,DCHS2,KLK6,PTCH1,BDNF-AS,PTN,PTPRD,ZNF615,OXR1,RASGRF2,RBBP6,REV3L,ERI2,MORC4,FIGN,SLC25A36,NUDT11,ZFHX4,CCDC82,ZNF532,CARF,ROBO1,ROBO2,ELP2,CCDC102B,RPE,BAALC,SPIN3,ZC3H14,TCP11L1,CLIP1,ZNF331,SALL1,ATXN7,FNIP1,ZFP2,SUPT20H,RASA3,CHD9,FNDC3A,FHOD3,NLGN1,NUBPL,WDR37,BTBD3,DHX30,CCDC88A,ELMO2,MAST1,LIMCH1,MBD5,PDZRN3,PDZD2,KDM3A,SP4,MYCBP2,KDM4C,ZC3H13,RBM26,LMO3,POGZ,LARP4,SS18,ERBIN,ST5,NEK4,SEPT8,DIP2A,SULF2,SEPT3,NECAB1,SYNE2,PLCB1,TMEM150C,SYT1,ANKRD28,ANKRD12,MTCL1,CAMTA1,ADGRL3,AGTPBP1,FBXW11,TCEA1,ZEB1,TRIM2,RPGRIP1L,CLASP1,SZT2,SYNE1,DOCK9,PCDHB7,PCDHAC2,PUM2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CCDC173,SIK3,ITGB3BP,TIAM1,HEY1,TPM1,STXBP4,TRPS1,ZNF610,EIF4ENIF1,UBE3A,UGT8,USP1,LGI4,ZFP37,ZIC2,ELFN1,ZNF540,TCEAL7,ZBTB38,TMEM237,EML6,EVI5,STOX2,PRDM8,TMEM178A,VPS35L,WNK3,PDSS2,RGS7BP,FAM13C,JMJD1C,SNX14,FXR1,NETO1,DPF3,JPH3" MicroRNA hsa-miR-380:mirSVR_highEffct hsa-miR-380:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-143 9.59E-140 9.59E-141 8.83E-140 353 1946 "ACADM,FMNL2,RNF157,PWWP2A,KIAA1211,ESYT2,ZNF608,PCDH19,HACE1,OSBPL1A,KIAA1324,OSBPL8,CC2D2A,ADGRF5,SMIM17,DOC2A,CDC42BPA,LRCH2,APAF1,APC,MAGEE2,DDO,SLC4A4,N4BP2L1,DPY19L3,ADAM23,BACH1,ADGRB3,LINC00847,MPDZ,NRP2,DST,MTMR2,SGCE,WASF1,IL33,CACNA1B,THSD7A,KALRN,PRC1,CLDN10,KRIT1,METTL6,ZMYM4,LRRFIP1,MAGI1,CCPG1,CLGN,CFL2,RCBTB2,CHGB,MS4A7,B4GALT6,NDST3,ARMC8,FAM149A,AKAP6,ABI3BP,FAM171B,C2CD2,CREM,HAPLN1,ANKRD44,SNCAIP,CSF2RA,CSNK1G3,SIPA1L1,UBXN2A,PUM1,CCDC144A,DOCK4,ARHGAP32,RIPOR2,DCAF8,ZFYVE16,KCTD8,DGKB,DAPK1,SCRN1,PABPC5,MYEF2,TIAM2,FBXL5,RHOBTB1,WDR20,ZNF582-AS1,GRIN3A,RAB39B,DMD,NR1D2,CDON,DPYSL2,DTNA,ECM2,GOLT1B,AASDH,EDIL3,EDN3,EDNRB,SEMA3D,KLHL5,FSD1L,PHF20L1,MBNL2,EIF4G2,PCOLCE2,VPS13B,CEP85L,ETV1,ADGRV1,CLVS1,FAM198B,ZNF461,ACSL4,FCGR1A,GORAB,SLC9B2,GTF2IRD2,FGFR1,FGFR3,FHL1,POLK,SUCO,MEX3B,IP6K2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,PSD2,SLC37A3,C2orf88,JKAMP,SMC2,ATP6V1H,MSANTD4,OGA,GALNT15,GABRB3,GAD1,ZNF274,MTHFD2,SYT17,C15orf41,DISC1,LRRC37A6P,IGSF5,SULT1C4,MSTN,MALT1,ZNF276,TXNL4A,RNPS1,ADGRA3,GPD2,FUT10,STON1,PCLO,DIDO1,BTN2A1,CLASRP,BVES,RABL2A,ATXN2L,HMGCR,LRRCC1,ZNF678,FAM69A,JAK2,KCND2,KCNJ16,KIF2A,STXBP5,LAMP2,LIG4,HECTD2,NCOA7,AQP11,MBNL1,ADAM11,MEF2C,MEIS2,KITLG,ZNF680,BLOC1S2,ADAM22,ZNF92,MYO9A,NF1,CNOT4,NTRK2,NUCB2,ZNF713,P2RX7,GPR137C,GLIPR1L2,CNTN3,PCDH8,PDE4D,ZDHHC8,GPSM2,PMP22,LRP12,SH3KBP1,PPM1B,PRKACB,CEP41,GRAMD1C,DIRAS2,RELN,VPS13C,SNRK,CNTLN,ANKHD1,TMEM260,STK32A,PTPRD,PTPRE,PTPRG,TMEM255A,RAD17,ZCWPW1,RBBP6,RADX,KHDRBS2,RDX,ERI2,FIGN,RFX3,UBR7,SLC25A36,RIC8B,ZFHX4,CCDC82,DCUN1D2,CARF,ROBO1,CCDC102B,ADAL,LRRK2,ZNF331,AP1AR,SATB1,CSRNP3,FNIP1,HES6,SGK1,ZFP30,KIF21A,SH3GL3,CPEB3,SHC4,CHD9,FNDC3A,NLGN1,PREX2,DHX30,WDR47,KANSL3,SEPHS1,SLC8A1,RADIL,CCDC88A,SLC12A2,RCOR3,SNAP25,LMBRD1,RBM34,SP4,UHRF1BP1L,MYCBP2,KDM4C,PEG10,ZNF423,ZC3H13,CDK19,RBM26,LMO3,ATP10B,CLASP2,ZNF302,LARP4,ERBIN,STAU1,CEP68,TTBK2,RGL1,PRRC2C,ADAMTS17,PLCB1,SYN2,SYPL1,TACC1,EXOC7,ADGRL3,AGTPBP1,FBXW11,KLHL4,SATB2,ZEB1,TCF12,SYNE1,DOCK9,PCDHB7,PUM2,FRYL,DICER1,ITGB3BP,CSMD1,C9orf85,STXBP4,TRPS1,DCBLD1,SGK3,UBE3A,UGT8,PLEKHH2,USP1,VSNL1,ZNF781,XRCC4,ZFP37,ZNF708,KCNT2,AGMO,LYPD6,TCEAL7,REEP1,SPIRE1,SMARCAD1,EMSY,EVI5,LINC02210,STOX2,RNF103,ADAMTS9,MDH1B,FAM47E,MPPE1,RGS7BP,FAM13C,RTN4,HNRNPA3,PHTF2,FBXO36,JMJD1C,RNF170,KLHDC1,FXR1,FRMD6,NETO2,NETO1,SENP7" MicroRNA hsa-miR-30c:mirSVR_highEffct hsa-miR-30c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.39E-143 1.34E-139 1.22E-140 1.12E-139 353 1948 "RALGAPA1,CLK4,ABHD6,GALNT16,CCDC85A,GALNT13,RNF157,ADD1,BRAP,KIAA1211,LRFN2,ADRB2,AP2A1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,C1QTNF3,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,UPRT,VAT1L,USP37,PPP4R4,TMEFF1,ZFYVE28,CADPS,TMEM108,STX16,ATP2B2,DPY19L3,ADGRB3,MPDZ,SEC11C,NRP2,BID,KSR1,DST,SYNJ2,SCAPER,MTMR2,CALB2,SLC25A14,CARS,CBS,USP2,SYNGR3,DGKI,SEPT7,ZBED1,L3MBTL4,LARGE1,MAGI1,DLGAP1,TIGD7,CFL2,CHN1,MS4A7,NDST3,NRXN3,FAM189A2,QKI,MAP4K4,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ZNF521,ZFP28,SLC35F1,CLOCK,GDA,SEC24C,OSBPL3,PDE4DIP,DZIP3,PHF14,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TBC1D5,MATR3,KCTD8,MAML1,SPATA2,YTHDC1,JAKMIP2,MYEF2,ALKBH8,PLPPR4,SACS,SPOCK3,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,MAMLD1,DNM1L,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,MBNL2,EGR3,ASB3,TENM1,PCOLCE2,TMEM35A,DCTN4,EPB41,EPB41L2,LRRC17,STX2,DENND4A,EXTL2,ABCA8,SH3YL1,SCML2,AMOTL2,SCARA3,UBE2E3,MEX3B,SYNCRIP,RGPD5,UFM1,ATP6V1H,KHDRBS3,NSG1,STAU2,MSANTD4,SARAF,OGA,ZMAT1,CHL1,TRAF3IP2,IP6K3,ERAP1,KIAA1841,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,TNRC6A,GNAO1,ADGRA3,PRUNE2,TDRKH,GRB10,GRIA2,CIT,FAM19A2,GUCY1B1,RASSF8,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,ZDHHC15,NEGR1,SMAP1,C2orf72,SOWAHA,ZIC5,ZNF678,FAM69A,LRRTM1,JAK2,KCND2,STXBP5,KTN1,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,CHIC1,MEIS2,MID1,PPM1L,MITF,ADAM22,NEFM,NEK1,NF1,SLC11A2,SMIM11A,NTRK3,NUCB2,OCRL,PCDH9,PCSK1,PDE4D,SNX10,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R5E,PRKACB,CEP41,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,TMEM260,PTPN13,USP47,OXR1,REV3L,PRRT2,ERI2,FIGN,SETD5,EXD2,CARF,PCMTD2,LRRK2,ABCA11P,RTN1,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN8A,SUPT20H,FRMPD1,ARX,KIF16B,CPEB3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,FAM81A,KANSL3,PKNOX2,TET1,ZFP1,RCOR3,TTC17,LIMCH1,TMCC1,MYO16,BDP1,DOK5,KDM3A,SP4,HECW1,RBM26,SPART,CLASP2,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,ELOVL4,NEK4,RGL1,SEPT3,STXBP1,SYPL1,COBL,TACR1,CAMTA1,MCF2L,ADGRL3,DMXL2,SATB2,USP22,CLASP1,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,SLC44A1,ACTR6,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,DCBLD1,ANKRD20A2,SSBP2,PRR18,CCDC14,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,LYPD6,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,SLC30A4,MAP3K12,STOX2,RNF103,ADAMTS9,HPS4,NAV3,FIP1L1,PARP11,AMN1,FZD3,DOCK8,MARCH8,HNRNPA3,PHTF2,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-1283:mirSVR_highEffct hsa-miR-1283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-142 1.05E-138 8.71E-140 8.02E-139 349 1915 "RALGAPA1,ACADM,CLK4,NCKAP5,SYS1,ADD1,PWWP2A,RNF150,ZNF608,INTS2,HECW2,HACE1,NME5,WDR35,OSBPL8,TAOK1,SRPX,BBOX1,UNC79,CDC42BPA,LRCH2,FGD2,CCDC146,PARG,SEMA4G,ARNTL,ATP2A2,ALDH7A1,DPY19L3,ATP6V1G2,TTLL9,MPDZ,SEC11C,MIR9-3HG,DST,SYNJ1,SCAPER,JAZF1,IL33,LURAP1,CALB1,CAST,CH25H,LRBA,CDH2,ZMYM4,L3MBTL4,NOG,CFL2,CHN1,CNOT8,TPP1,FAM19A5,C4orf33,QKI,SULT4A1,HECTD1,HOMER3,CNTN1,AKAP6,SUMF2,RCHY1,ZFP28,SLC35F1,CDC42BPB,PREPL,CREM,CRHBP,HINFP,CRYM,SNCAIP,SEC24C,SUSD5,SIPA1L1,SOCS5,CNTNAP2,UBXN2A,PUM1,CCDC144A,HDAC9,ZFYVE16,MATR3,MAML1,TMEM170A,DAPK1,MYEF2,DDX46,ALKBH8,RHOBTB1,PLPPR4,SNAP91,SACS,DYNC1I1,CDON,CPEB2,CASP8AP2,ECM2,GOLT1B,EBF1,EDNRA,PHC2,HIPK3,FRY,YAF2,PHF20L1,APH1A,MBNL2,EGR3,EIF4G2,COPS4,PLEKHA1,RGS17,GPHN,CEP85L,CDKL3,VPS26C,TMEM132C,TAOK3,SCML2,CEP78,GTF2IRD2,FGF12,FGF14,TMEM164,UBE2E3,MEX3B,PCYOX1,SYNCRIP,C2orf88,TMEM107,STAMBP,ST6GALNAC3,SARAF,MEGF10,GABRG2,TRAF3IP2,GAD1,RAPGEF6,DISC1,KIAA1841,NEU3,MSTN,PPARGC1A,MALT1,COPS8,RNPS1,SPIN1,RAB30,GPR75,TNRC6A,GLUL,ZNF638,KDM2B,HTATSF1,GNAO1,FUT10,STON1,GPR37,FAM19A2,ZBTB49,PSIP1,HMGCR,HNF4G,SHISA6,SOWAHA,RBPJ,KIAA1755,FAM69A,LRRTM1,NME9,ITPKB,KIF2A,STXBP5,KTN1,LAMP2,HECTD2,NCOA7,MAN2A2,MAP4,MATN3,LRP1B,MEF2C,SRSF12,MIA2,AFDN,COMMD5,ADAM22,TCEAL5,HNRNPM,NEK1,NOVA1,NPTX1,NPTX2,SLC11A2,SMIM11A,TBC1D25,CLDN11,DPY19L2P2,PCDH8,PDE4D,ENPP2,GPR85,PFKFB2,TMEM38A,PRIMPOL,MAPKAP1,DRAM2,PPP2R5E,PPP3CA,MAPK9,HYDIN,DIRAS2,PRPSAP2,GDPD2,CNTLN,PTCH1,PTK2,PTN,TMEM260,PTPRB,CASTOR1,PEX2,USP47,FAT4,NWD1,RAP1GDS1,ZNF493,OXR1,RBBP6,RBBP8,KHDRBS2,ZDHHC14,RDX,RFX3,UBR7,NUDT11,PBRM1,ZFHX4,SETD5,CARF,RORB,YY1AP1,MRAP2,RPL15,ARMH4,FBXW7,LRRK2,ABCA11P,NCBP3,ZNF331,SATB1,ATXN2,ATXN7,FNIP1,HES6,TRA2B,SH3GL3,FERMT1,SHC4,CHD9,FBXO11,FHOD3,ABLIM3,FAM81A,BTBD3,WDR47,SEPHS1,ARHGEF40,SLC11A1,SLC12A2,MTERF2,ATF7IP,CPEB4,RCOR3,SNAP25,MBD5,KIF13A,SNRPN,FAM126B,PDZRN3,MYO16,USP33,BDP1,SP4,MCF2L2,RBM26,TROVE2,THSD1,LARP4,NKAIN2,SULF2,VPS13A,SYT1,COBL,MTCL1,TAL1,ALG1,ADGRL3,KLHL4,TCF4,DMXL2,TRIM2,PCDHGA11,HIF3A,FAM200B,SIRT1,ITGB3BP,SLC44A1,ERCC6L2,TMPO,KAT6B,TP53BP2,TPM1,RGMB,METTL3,STXBP4,DCBLD1,ZKSCAN5,RPL7L1,UBE3A,UBTF,PLEKHH2,TBC1D15,CLDND1,ZNF24,ZNF28,KCNT2,AGMO,LYPD6,CELF4,FSTL5,ZNF189,ZNF195,EMSY,MFF,NAV3,FIP1L1,MPPE1,PLSCR4,FZD3,UBE3B,SMIM8,HNRNPA3,JMJD1C,NLRP3,TIGD6,SNX14,KLHDC1,SENP7" MicroRNA hsa-miR-589*:mirSVR_highEffct hsa-miR-589*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.33E-142 3.54E-138 2.73E-139 2.51E-138 344 1866 "ABCF1,KCNH8,ABR,ABHD6,NCKAP5,CCDC85A,GALNT13,AXIN2,ADRB2,BEND6,INTS2,HECW2,KCTD16,OSBPL8,SPOP,ALCAM,FAM135A,LRFN1,DPP10,EP400,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,UPRT,USP37,MADD,ARRB2,TMEM108,STX16,N4BP2L1,RIPK1,SEC11C,BMP7,DST,IL33,CA12,KALRN,PTBP2,CAMK2B,CAMK2G,CAST,CBLN1,ZNF501,USP6,CBFA2T2,SEPT7,MAGI1,CDO1,CCPG1,CLGN,RCBTB2,CLCN3,AKAP7,IQCK,ARMC8,ABI3BP,COX4I1,AHCTF1,MYRIP,ZNF385A,CREM,RBM39,CS,SNCAIP,PLXNA4,ERC2,PHF14,PPP6R2,RUBCN,CYBB,DOCK4,HDAC9,ZFYVE16,ZNF337,RASSF2,LIN54,KCTD8,IST1,IP6K1,PABPC5,GIT2,ZBTB24,ZC3H11A,RHOBTB1,WDR20,DLX1,GRIN3A,DMTF1,DPYSL2,ECM2,E2F6,EDN1,FAM13A,SUGP2,MBNL2,KMT5B,EIF4G1,STARD3NL,VPS13B,LRRC17,EPHB1,GPHN,RABEPK,ETV1,ANKMY1,EYA1,ABCA8,NSRP1,DLC1,FCGR1A,CEP78,ZNF589,FGF11,FGFR1,PRKAG2,SUCO,SLC37A3,PDLIM5,KHDRBS3,ST6GALNAC3,NSG1,NEURL4,GABRG2,GAD1,RAPGEF6,IQGAP2,C15orf41,DISC1,INPP5K,ACSS1,GCNT2,AHDC1,USP19,GHR,PPARGC1A,SPIN1,GPR75,ZNF638,LUZP2,KCNMB4,CCDC184,TMEM121B,PCLO,GRB10,GRIA2,RNF165,COQ10A,ZBTB49,FRMD3,MIER3,VSIG4,SOWAHA,GAREM2,TJAP1,KCND1,KLHL23,KCNJ16,KIF5A,KPNA5,STMN1,PAXBP1,HECTD2,PACRG,SMAD1,MAP2,MAP4,MARK1,LYPLAL1,MAT2A,MBD1,SHC3,AFDN,ADAM22,MYCN,NEFM,NEFH,NF1,NFE2L2,ALDH1L2,CNOT4,NPR2,NPTX2,NTRK2,NUCB2,IGSF11,OXTR,GPR137C,ZNF827,PCDH9,PDE4D,ENPP2,GPR85,GNG2,OLA1,NLGN3,CCSER2,PLXNB1,TRHDE,STRN3,LRP12,EXOSC10,MAGEL2,EPB41L4B,POLG,DRAM2,PPM1B,TATDN3,PPP3CA,HYDIN,RELN,CNNM2,NDUFS7,SAMD9,WBP1L,SNRK,PIGG,PTCH1,BDNF-AS,TMEM260,PTPRB,PTPRO,ZNF615,USP47,SUSD4,NWD1,ZCWPW1,RASGRF2,MSANTD2,RDX,ERI2,GTDC1,SLC25A36,ZFHX4,ZNF532,C12orf49,CARF,GSTCD,ROBO1,CCDC25,RORB,ELP2,RPE,SPIN3,LRRK2,MEG3,KCNIP1,CLIP1,TRAPPC13,SAFB,SATB1,ATXN7,SCN8A,FNIP1,CASC3,ARX,CPEB3,FBXO11,ST6GAL1,NLGN1,SLC2A5,PEX26,SEPHS1,ATF7IP,SLC22A4,RCOR3,TMCC1,USP33,DOP1A,BDP1,DOK5,SP4,HECW1,KDM4C,TEX2,PEG10,ZC3H13,CLSTN2,ITPRID2,SEPT8,STX1A,KANK1,SYNE2,VPS13A,PLCB1,SYN2,ANKRD28,MMS19,PJA1,FAM208A,ADGRL3,TBCEL,ZFP90,GPRIN3,DNAH7,PMS2CL,ITGB3BP,AP4E1,SLC44A1,TIAM1,ERCC6L2,PRRT1,KAT6B,TNS1,SYNPO2,METTL3,RUNDC3B,TRO,TSN,ANKRD20A2,RPL7L1,USP1,WIPF1,KLC2,CLDND1,ZBTB14,ZNF24,MICU3,KCNT2,TRIM9,ZSCAN26,INTS3,EMSY,MFF,PRTFDC1,GDPD5,LINC02210,STOX2,ADAMTS9,HPS4,FIP1L1,ITM2C,WNK3,PDSS2,FAM13C,HNRNPA3,PHTF2,CASC15,ACTR3B,ADAMTSL3,NLRP3,IFT88,FAM198A" MicroRNA hsa-miR-30b:mirSVR_highEffct hsa-miR-30b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.92E-141 1.08E-137 7.69E-139 7.08E-138 346 1895 "RALGAPA1,CLK4,ABHD6,GALNT16,GALNT13,RNF157,ADD1,BRAP,KIAA1211,LRFN2,ADRB2,AP2A1,AP2A2,ZNF608,INTS2,KCTD16,HACE1,TAOK1,C1QTNF3,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,VAT1L,USP37,PPP4R4,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B2,DPY19L3,ADGRB3,SEC11C,NRP2,BID,KSR1,DST,MTMR2,CALB2,SLC25A14,CARS,CBS,LDB2,USP2,SYNGR3,DGKI,SEPT7,ZBED1,L3MBTL4,LARGE1,MAGI1,DLGAP1,TIGD7,CFL2,MS4A7,NDST3,NRXN3,FAM189A2,QKI,MAP4K4,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ZNF521,ZFP28,SLC35F1,CLOCK,GDA,CRYM,SEC24C,OSBPL3,PDE4DIP,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TBC1D5,MATR3,KCTD8,MAML1,YTHDC1,JAKMIP2,MYEF2,ALKBH8,PLPPR4,SACS,SPOCK3,WDR20,RAB39B,DMD,CPEB2,SLC12A6,PDCD6IP,MAMLD1,DNM1L,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,MBNL2,EGR3,ASB3,TENM1,TMEM35A,DCTN4,EPB41,EPB41L2,LRRC17,STX2,DENND4A,EXTL2,ABCA8,SH3YL1,SCML2,FCGR1A,AMOTL2,SCARA3,UBE2E3,MEX3B,SYNCRIP,RGPD5,UFM1,ATP6V1H,KHDRBS3,NSG1,STAU2,MSANTD4,SARAF,OGA,ZMAT1,CHL1,TRAF3IP2,IP6K3,ERAP1,KIAA1841,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,TNRC6A,GNAO1,ADGRA3,PRUNE2,TDRKH,GRB10,GRIA2,CIT,FAM19A2,GUCY1B1,RASSF8,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,ZDHHC15,NEGR1,SMAP1,C2orf72,SOWAHA,ZIC5,ZNF678,FAM69A,LRRTM1,JAK2,STXBP5,KTN1,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,CHIC1,MEIS2,MID1,PPM1L,ADAM22,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,PCDH9,PCSK1,PDE4D,SNX10,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R5E,PRKACB,CEP41,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,TMEM260,PTPN13,USP47,OXR1,REV3L,PRRT2,ERI2,FIGN,SETD5,EXD2,CARF,PCMTD2,LRRK2,ABCA11P,RTN1,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN8A,SUPT20H,FRMPD1,ARX,KIF16B,CPEB3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,FAM81A,KANSL3,PKNOX2,TET1,ZFP1,RCOR3,TTC17,LIMCH1,TMCC1,MYO16,BDP1,DOK5,KDM3A,SP4,HECW1,RBM26,SPART,CLASP2,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,ELOVL4,NEK4,RGL1,STXBP1,SYPL1,COBL,CAMTA1,MCF2L,ADGRL3,DMXL2,SATB2,USP22,CLASP1,SYNE1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,TMEM121,SLC44A1,TMEM9,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,DCBLD1,ANKRD20A2,SSBP2,TTC3,CCDC14,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,LYPD6,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,SLC30A4,MAP3K12,STOX2,RNF103,ADAMTS9,HPS4,NAV3,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,HNRNPA3,PHTF2,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-33b:mirSVR_lowEffct hsa-miR-33b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.18E-141 1.78E-137 1.19E-138 1.09E-137 354 1989 "SYN3,CLK4,SYS1,KLHL32,GALNT13,ADD2,KIAA1211,PTCHD1,SLC24A4,HECW2,KCTD16,TBC1D14,NME5,OSBPL6,C1QTNF3,SPARCL1,SMIM17,ALCAM,PCDH10,AMPD2,ZFAT,OGT,LRCH2,ANK2,CCDC146,LCORL,MAP4K3,PKP4,APBA2,APC,UPRT,LGR5,SFMBT2,PPP4R4,NUMB,EIF4G3,ATP6V0A1,LINC00847,MPDZ,SEC11C,BLM,KSR1,FUBP1,WASF1,CA8,CABP7,CAMK2G,ISPD,SEPT7,ZBED1,LRRFIP1,LOC730101,TIGD7,CLGN,CBARP,MS4A7,NDST3,PLAA,AHCTF1,ZFP28,CREM,RBM39,GDA,ARHGEF10,CSNK1G3,CST3,DZIP3,APPL1,PLCXD3,BOC,TCAF1,RIPOR2,DCAF8,ZNF337,MATR3,KCTD8,PABPC5,SPATA2,KIAA0319,DDX46,RHOBTB1,SPOCK3,EXOG,DNAH9,CPEB2,SLC25A18,DTNA,AASDH,EDN1,EDNRA,CNNM1,FRY,YAF2,PHF20L1,SUGP2,MBNL2,KMT5B,GOLGA7,EIF4G2,PCOLCE2,STARD3NL,USPL1,LRRC17,GPHN,IGSF6,ZNF549,MRPL37,CDKL3,SIRPB1,MRVI1,TMEM132C,ACSL4,SCML2,CHST15,GORAB,SEC24B,SLC9B2,MED12L,GTF2IRD2,SCARA3,MEX3B,SYNCRIP,FLT1,ANKFY1,APOPT1,PDLIM5,ZNF605,STAU2,MSANTD4,FYN,MEGF10,RAPGEF6,MTHFD2,DISC1,CYP46A1,ADAM28,GHR,PPARGC1A,COPS8,DBF4,SPIN1,GLI2,TOX3,KDM2B,RAB40B,FERMT2,ADGRA3,LILRA2,GPR37,PCLO,ATP2B1-AS1,GRIA2,GRM2,ZBTB49,AP4S1,LINGO1,PSIP1,GUCY1B1,FRMD3,MIER3,SYNPO,SHISA6,CELF5,EID2B,C2orf72,SOWAHA,SCIN,INPP5B,INSM1,SLC35G1,KCNN2,CREG2,KPNA5,CYP27C1,KTN1,LAMP2,LIMS1,LMO2,NCOA7,MAP6,MBD1,MEF2C,MID1,XRRA1,MMP16,ZNF680,SAMD5,ZNF92,TAGLN3,MYCN,MYO9A,P2RY13,NELL2,NF1,NFIX,NOVA1,DNHD1,NTRK2,OGG1,OPA1,OXTR,GPR137C,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDE4A,PDE4B,SLC10A4,NLGN3,NALCN,SEMA5B,XRN1,GPSM2,FAM216A,ANKRD16,MAPKAP1,STRN3,LRP12,EPB41L4B,SH3KBP1,PPP2R5E,KANSL1,PKIA,EPDR1,DIRAS2,SNRK,PTPRN2,PTPRO,ACSM5,QDPR,PID1,FAM66C,ZNF793,SH3TC2,FAM184A,RET,FIGN,ZDHHC4,SLC25A36,ZFHX4,LGI2,ZNF532,ROBO1,ROBO2,CCDC25,ZC3H14,ZNF671,STK32B,MAP6D1,ABCA11P,KCNIP3,RTN1,AP1AR,CSRNP3,SCN2B,TNFRSF19,PEAR1,CASC3,GALNT10,SH3GL3,KIF16B,FBXO11,ST6GAL1,NLGN1,ANKRD6,ABLIM3,PREX2,SLC2A5,BTBD3,DHX30,SLC12A2,SMARCD3,RCOR3,ANKRD36,LIMCH1,MBD5,KIF13A,PDZD2,BDP1,HECW1,SPP1,NFASC,SSTR2,SS18,ERBIN,STAU1,ZSCAN29,SEPT3,STXBP1,NECAB1,JMJD6,SYNE2,PLCB1,ANKRD28,TAF9,DNMBP,ADGRL3,KIAA1107,TCF4,ZFP90,RPGRIP1L,TCF12,SYNE1,PCDHB7,USP32P1,SLC35G2,FRYL,PMS2CL,SIRT1,AP4E1,ZMAT3,AKTIP,ARL10,ACTR6,RIMBP2,R3HDM1,KAT6B,TNS1,TPM1,C9orf85,SYNPO2,METTL3,TRPS1,TSC1,TUBB1,RPRM,FLRT2,VSNL1,WRN,GUSBP1,XPO1,SLC47A2,PCDH20,ZIC2,KCNT2,MKRN3,TCEAL7,ZBTB38,ANKS1B,ZFAND5,SMARCAD1,PRTFDC1,RNF103,TMEM178A,KCNAB1,MPPE1,RTN4,UBE3B,CASC15,TTC7A,KLHDC1,FXR1,NETO1" MicroRNA hsa-miR-130a:mirSVR_lowEffct hsa-miR-130a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.15E-141 2.32E-137 1.45E-138 1.34E-137 332 1744 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,PWWP2A,AK2,ADGRF5,ABCD2,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,MYH7B,APBB2,EPB41L5,TNRC6C,LGR5,SLC4A4,ATP2A2,ZNF582,DOCK11,KSR1,BMPR1B,SGCE,GPC2,LDLRAD4,CALB1,CAMK2G,RUNX1T1,USP2,ENTPD6,SEPT7,CDH2,MAGI1,NOG,SRSF11,MS4A7,FBXO7,C4orf33,QKI,HECTD1,RAB26,FHL5,IQCK,SLC4A8,BAG4,ZNF521,HAPLN1,SIPA1L1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,ELMO1,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,NYAP1,USP3,DNAH9,MED12,NR1D2,SLC12A6,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,RABEPK,SLC43A2,CEP85L,TLR7,KATNAL1,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FKTN,FECH,OLFM1,AMOTL2,SCARA3,MEX3B,PCYOX1,ANKFY1,JKAMP,STAU2,GABRA3,ZNF44,GABRG1,ZNF274,IQGAP2,C15orf41,TUBGCP4,AHDC1,PCDH17,PPARGC1A,DBF4,TOX3,GPT2,ADGRA3,GPR12,MCHR1,GPER1,PCLO,GRIA2,GRM2,LINC01089,KAT7,SOX21,GUCY1A1,MAP4K5,FAM222A,HAS2,FRMD3,MIER3,HLF,SYNPO,AGBL5,AGFG1,SHISA6,CELF5,IGF1,NIM1K,SLC35G1,KCNN2,KCNQ3,KIT,IPO5,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LRP1B,KITLG,AFF1,ZNF680,ADAM22,IDNK,NELL2,NFYA,NOVA1,NPTX1,NPTX2,TBC1D25,OPA1,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,FAM216A,PDZRN4,STRN3,ING3,POU6F1,PKIA,HYDIN,RELN,VPS13C,DEF8,ZIK1,PTPRD,PPP2R3C,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,FIGN,RFX3,UBR7,RGS3,RIC8B,RNASEL,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,GLDN,RYR3,ZNF331,SALL1,SATB1,SCN8A,TNFRSF19,GALNT10,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,WDR37,SLC12A2,CPEB4,GKAP1,MAST1,RCOR3,CABCOCO1,SNRPN,KDM4B,FNBP1,KDM3A,ZSWIM8,KDM4C,PEG10,ZBTB43,TSPYL2,RBM26,ATP10B,LARP4,SEPT8,DIP2A,KANK1,STXBP1,SYT1,ANKRD28,TACC1,TACR1,EXOC7,PDLIM2,AGTPBP1,TBCEL,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,SYNE1,DOCK9,PHF24,PCDHB7,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,CYB561A3,RIMBP2,PARD3,RASD2,NPL,RGMB,NR2C2,SMUG1,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,LINC00689,BCL2L13,TOM1L2,VLDLR,P2RY12,RICTOR,XRCC4,PCDH20,ZNF24,LYPD6,CELF4,SPIRE1,SMARCAD1,UPF3A,EMSY,EVI5,LINC02210,NAV3,KCNAB1,FAM47E,WNK3,PDSS2,FAM13C,DOCK8,FBXO36,CASC15,FAM219B,RNF170,TTC7A,NETO2,SOCS4,CPNE4,JPH3" MicroRNA hsa-miR-429:mirSVR_highEffct hsa-miR-429:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.76E-141 4.34E-137 2.56E-138 2.35E-137 345 1892 "KCNH8,ACHE,CLK4,SYS1,XKR4,FMNL2,PWWP2A,PTCHD1,SLC24A4,MTUS1,HFM1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,LCORL,MAP4K3,PKP4,PARG,VAT1L,SHROOM2,CDC14B,IGDCC4,NUMB,STX16,ATP2A2,DPY19L3,MPDZ,PROM1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,IL33,CA8,THSD7A,PTBP2,CAST,SPAG9,CD86,ZMYM4,NOG,CACNA2D2,CFL2,CHN2,NDST3,FAM19A5,QKI,CNN3,CNTFR,AKAP7,SLC4A8,GAL3ST1,BAG4,HINFP,GDA,CS,CSF1,SEC24C,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,USP6NL,CCDC144A,DOCK4,GPRASP1,ARHGAP24,DCAF8,LIN54,MATR3,KCTD8,TMEM170A,GIT2,ELMSAN1,ZBTB24,MYEF2,RUSC2,PLPPR4,WDR20,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DYNC1I1,CPEB2,DTNA,MAMLD1,DNAJB6,CNNM1,TMTC1,FSD1L,EGR3,GOLGA7,EIF4G2,PAN3,MTSS1L,ETV1,CLVS1,ACSL4,TAOK3,DLC1,FER,POLR1B,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXF2,ATP13A4,ANKFY1,NOP56,JKAMP,APOPT1,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,MSANTD4,OGA,FYN,ZNF274,KIAA1841,GATM,MSTN,SESN1,FREM1,GHR,MALT1,COPS8,TNRC6A,FERMT2,GRIA2,FAM19A2,PSIP1,MAP4K5,RASSF8,MIER3,HLF,NEGR1,AGFG1,SHISA6,ZNF181,TJAP1,IL12A,KCND2,KCNJ16,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LRP1B,MEIS1,MEST,MYCN,CNOT4,NOVA1,NPTX1,SLC11A2,SMIM11A,NTRK2,NUCB2,IGSF11,CHAMP1,PCDH8,PCSK1,PRTG,PDE4B,GPR85,GNG2,SERPINI1,NALCN,FAM218A,SNX10,XRN1,KCTD15,PLCL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SNRK,PTCH1,BDNF-AS,MTMR10,TMEM260,PTPN13,PTPRD,EML5,ZSCAN2,FAT4,OXR1,RADX,MSANTD2,RDX,REV3L,ERI2,FIGN,SLC25A36,NUDT11,RNASEL,CCDC82,ZNF532,CARF,ROBO1,RORB,CCDC102B,RPE,ARMH4,FBXW7,KIAA0895L,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,SEMA6D,SCN8A,SCP2,SUPT20H,KIF21A,SHC4,AMBRA1,FBXO11,FNDC3A,R3HDM2,SEC31A,ANKRD6,SLA,FAM81A,KDM4D,SLC12A2,SLC14A1,ZNF667,MYH15,SNAP25,MBD5,KIF13A,SNRPN,TMCC1,FAM219A,PDZD2,BDP1,DOK5,KDM4C,ZNF423,SPART,CLASP2,TROVE2,POGZ,ITPRID2,ZNF302,NKAIN2,MPRIP,SEPT8,RGL1,DIP2A,PHLDB1,KANK1,SYNE2,VPS13A,SYT1,ANKRD28,ANKRD12,ADGRL3,FBXW11,SATB2,ZEB1,CLASP1,PCDHB9,PUM2,GPRIN3,CCDC173,RNF216P1,ZFPM2,HEY1,ASXL3,ERCC6L2,CSMD1,TRIO,RUNDC3B,AMACR,TUBB2A,FAM155A,UGT8,BCL2L13,VLDLR,TBC1D15,RBFOX3,WIPF1,CLIP2,GUSBP1,XPO1,XRCC4,ZNF711,ZNF23,TRIM9,MKRN3,LYPD6,TCEAL7,ZBTB38,REEP1,TFIP11,SMARCAD1,PRTFDC1,EVI5,TMEM178A,NAV3,FAM13C,KAT6A,PHTF2,NLRP3,TRAM2-AS1,RNF170,KLHDC1,FXR1,IFT88,GAN" MicroRNA hsa-miR-654-3p:mirSVR_lowEffct hsa-miR-654-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-140 1.75E-136 9.73E-138 8.96E-137 344 1889 "RALGAPA1,CLK4,ACTN1,NDRG3,TMEM132B,PLEKHH1,ESYT2,ADRA1D,SLC24A4,INTS2,NME5,WDR35,OSBPL8,AK2,ZNF578,ADGRF5,CARNS1,PCDH10,BEGAIN,ZFAT,DPP10,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,DDO,PHYHD1,CDC14B,ARNTL,NCOA1,NUMB,RASL11B,STX16,ATP2A2,SLC2A11,ATP6V0A1,BACH1,SCAPER,SGCE,CACNA2D1,CALB2,CALM1,VXN,PRC1,KYAT1,USP6,LRBA,LRRFIP1,MAGI1,DLGAP1,CCPG1,CACNA2D2,SRSF11,CHGB,NDST3,NRXN3,LY86,CNTFR,AKAP6,SUMF2,LETMD1,MAGED1,TBPL1,SMARCAL1,MYRIP,PREPL,HAPLN1,ANKRD44,GDA,SNCAIP,SEC24C,OSBPL3,VAC14-AS1,PHACTR3,SLITRK5,KIAA0040,PLCXD3,BOC,DOCK4,SNPH,EARS2,TBC1D5,MATR3,DGKB,TMEM170A,DAPK1,SCRN1,SPATA2,MYEF2,GSDME,SPOCK3,CD99L2,DOCK2,ECM2,FARSB,GOLT1B,AASDH,WDPCP,EDN3,EDNRB,PHC2,FCF1,SEMA3D,TMTC1,CELSR3,PHF20L1,SUGP2,MBNL2,RASA4,AASS,GOLGA7,COPS4,PLEKHA1,CERCAM,CALCRL,EPHB1,DENND4A,DNAJC27,RASL12,FAM198B,TMEM132C,DLC1,CHST15,ZSCAN30,ZNF589,GORAB,OLFM1,FGF12,FGF14,AMOTL2,POLK,MEX3B,HPCAL4,SYNCRIP,FOXO3,EVL,ANKFY1,PSD2,COQ5,WDR83,STAU2,MEGF11,IQGAP2,CPLX2,KIAA1841,ARFIP1,CYP46A1,GHR,COPS8,SPIN1,LUZP2,GPR12,CCDC184,TMEM121B,ATE1,PSIP1,ATOH8,RASSF8,HAS2,ZNF491,KIAA1755,INSM1,SLC35G1,KCND2,KIF2A,KIF5A,A1BG-AS1,STXBP5,L1CAM,HECTD2,NCOA7,GPR155,ZFYVE27,MARK1,LYPLAL1,LRP1B,MEIS1,MEIS2,PPM1L,MMP16,GIT1,COL28A1,DBNL,SAMD5,THYN1,LAYN,MYO6,MYO7A,ZNF862,P2RY13,NF1,DNHD1,SLC11A2,NTRK2,NTRK3,CHAMP1,CLDN11,P2RX7,GPR137C,PFKFB2,TMIE,CCSER2,SNX10,PURG,ANKRD16,SCHIP1,DRAM2,PPM1B,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,MAPK3,MAPK10,MASP1,SAMD9,GDPD2,CNTLN,MTMR10,PTN,TMEM260,ZIK1,PTPRB,PTPRD,C1orf109,TUG1,TMEM231,MARCH1,RAD51D,FAM66C,RASGRF2,ZDHHC14,RDX,ZMAT4,REV3L,GTDC1,RGS3,RGS12,SLC25A36,NUDT11,RNH1,DCUN1D2,CARF,CCDC102B,SPIN3,STK32B,FAM161B,CLIP1,RYR3,NCBP3,ZNF331,FAM192A,SBF1,CSRNP3,ATXN7,ZFP2,PEAR1,MRAS,SCAF8,R3HDM2,NLGN1,SEC31A,SLC2A5,PKNOX2,SLC8A1,ELMO2,EPC1,COA1,SMARCC2,CDK5RAP2,RCOR3,LIMCH1,SNRPN,FAM126B,KDM3A,PEG10,SPTB,TSPYL2,RBM26,NFASC,ZNF302,SS18,SEPT8,TTBK2,SULF2,ARHGEF9,NUDT10,PLCB1,SYT1,C12orf76,TACR1,CAMTA1,TAF6,MLST8,IQCE,SYNE1,DOCK9,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AKTIP,TIAM1,BHLHB9,NPL,C9orf85,RGMB,NR2C2,TRO,TRPS1,DCBLD1,UBE3A,PLEKHH2,MTCH1,PLPPR2,GUSBP1,XRCC4,CFAP298,ZIC1,MICU3,ELFN1,LYPD6,ZNF138,REEP1,ANKS1B,PRTFDC1,DNALI1,STOX2,RNF103,URM1,FAM47E,PDSS2,DOCK8,HNRNPA3,JMJD1C,RNF170,KLHDC1,FRMD6" MicroRNA hsa-miR-3151:mirSVR_lowEffct hsa-miR-3151:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.13E-140 3.43E-136 1.81E-137 1.66E-136 340 1848 "ABR,SYN3,ASIC1,SYS1,TMCC3,RNF157,ADD1,PLEKHH1,UNC5A,PTCHD1,ADRA1D,OLMALINC,MTA3,AP2A2,ZNF608,HECW2,TXNDC16,SEMA6A,PCDH10,LTBP4,PITPNM2,AMPD2,AMPD3,LRFN1,OGT,PI16,MYH7B,PHYHD1,SEMA4G,IGDCC4,ARHGDIA,LINC00173,MARCH3,PCDHGB4,TMEM108,CHID1,ATP1A3,RNF182,CFLAR,ARHGEF7,BTK,JAZF1,GPC2,MYRF,DDR1,CACNA2D1,CALB2,CABP7,CALM1,KALRN,CAMK2A,CAST,MTMR7,CBFA2T2,SCARB1,SYNGR3,ZMYM4,EVI5L,L3MBTL4,TIGD7,NOG,CACNA2D2,TAOK2,LHX2,IGLON5,IQCK,FAM149A,COL11A2,CREM,SH2B1,ANKRD44,CSNK1E,CST3,SLITRK5,CTH,GREB1,GPSM1,CYBB,MYADM,ARHGAP32,RIPOR2,ARHGAP24,TM9SF4,TBC1D5,INTS1,MAML1,SPOCK2,AIF1L,PITPNC1,RUSC2,TMEM130,ZC3H11A,SGSM2,TMCC2,MED12,SLC29A4,NR1D2,DTNA,E2F5,EDN1,FRY,EGR3,TMEM132E,TENM1,C3orf18,ENO2,EPB41L2,LRRC17,RAB9B,ERBB2,ANKMY1,MRVI1,EZH1,HSPA12B,REEP2,CLVS1,FCGR1A,ZMYND10,FCGRT,FGF11,FGFR3,MEX3B,HPCAL4,IP6K2,AGAP3,EVL,C2orf88,TMEM107,TRIM16,RASL10A,CAMKK2,KHDRBS3,ST6GALNAC3,CSPG5,TVP23A,FYN,NEURL4,B4GALNT1,INPP5K,ACSS1,GCK,ADAM28,CSDC2,GGT7,GGT5,NTNG2,STARD3,POLL,LNX1,DIDO1,GRM2,ZNF496,ZBTB49,RABL2A,LINGO1,SLC2A6,UBE2QL1,AGBL5,HNF4G,NEGR1,SHISA6,SMAP1,IDH3B,MYLK2,ZNF546,NKD1,KIAA1755,INPP5B,KCNB1,KCNH2,KCNK3,KCNN1,GATD1,KHK,KIT,L1CAM,STMN1,SFXN5,PIK3AP1,CHIC1,MX1,LYRM9,LAYN,P2RY13,NFIX,NNAT,NME4,DNHD1,NPTX2,OCRL,OGG1,OPA1,ZNF827,DPY19L2P2,PCDHGC3,CDK18,SEMA5B,FAM218A,PKM,SLC25A23,PCDH18,MAPKAP1,EXOSC10,RETREG2,POLG,VSTM2L,HYDIN,MASP1,BCAS3,WBP1L,CYBC1,PIGG,PTPRB,PTPRN,NKAIN1,CCDC40,NWD1,ZMAT4,FIGN,UBR7,RGS3,RNASEL,LGI2,SETD5,ARMC5,CARF,KIAA0895L,GLDN,HSD11B1L,ATAT1,ZNF331,MAPK12,ATXN2,SCP2,FOXRED1,SCAF8,SH3BP2,FAM102A,PPM1E,FNDC3A,R3HDM2,ANKRD6,FAM81A,SLC2A5,LIMS2,PKNOX2,SLC6A8,SLC8A1,SIRT2,SLC12A4,OGDHL,CDK5RAP2,SMARCD3,SNRPN,SOX3,SP2,IZUMO4,TSPYL2,LHPP,CLSTN2,CAMTA2,SSPO,ZSCAN29,DIP2A,STAC2,STX1A,KANK1,NSFL1C,PRRC2C,SYP,COBL,SYT5,PDLIM2,DMXL2,CUX2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,TNS2,CYB561A3,DICER1,ZNF106,FAM124A,PRRT1,R3HDM1,CABIN1,TPM2,WBP2,RGMB,ELP5,TRIO,TRO,TSC1,TTC3,GORASP1,OSBP2,CCDC136,RBFOX3,WIPF1,CLIP2,CLDND1,XRCC4,KCNT2,ZNF142,REEP1,POLR3H,TMEM198,DPYSL5,ZNF213,MEIS3,INTS3,MAP3K12,PRTFDC1,DNALI1,STOX2,PRDM10,CIAPIN1,GAL3ST3,NAV3,PCBP4,PLD4,PARP11,RGS7BP,SMIM8,HNRNPA3,TMEM63C,RNF170,TTC7A,NETO1,DPF3" MicroRNA hsa-miR-200b:mirSVR_highEffct hsa-miR-200b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.80E-140 5.48E-136 2.74E-137 2.52E-136 335 1795 "KCNH8,ACHE,CLK4,SYS1,XKR4,PWWP2A,PTCHD1,SLC24A4,INTS2,MTUS1,HFM1,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,ANK2,LCORL,MAP4K3,PKP4,PARG,VAT1L,SHROOM2,CDC14B,IGDCC4,NUMB,STX16,ATP2A2,DPY19L3,ADGRB3,MPDZ,PROM1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,IL33,CA8,THSD7A,PTBP2,CAST,SPAG9,ZMYM4,NOG,CFL2,CHN2,FAM19A5,QKI,CNN3,CNTFR,AKAP7,SLC4A8,GAL3ST1,BAG4,GDA,CS,CSF1,SEC24C,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,USP6NL,CCDC144A,DOCK4,GPRASP1,ARHGAP24,DCAF8,ZFYVE16,LIN54,MATR3,KCTD8,TMEM170A,GIT2,ELMSAN1,ZBTB24,MYEF2,RUSC2,PLPPR4,WDR20,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DNAH9,DYNC1I1,CPEB2,DTNA,MAMLD1,DNAJB6,CNNM1,TMTC1,FSD1L,YAF2,EGR3,GOLGA7,EIF4G2,PAN3,TUBD1,MTSS1L,TAOK3,DLC1,FER,POLR1B,FGFR1,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXF2,ATP13A4,ANKFY1,NOP56,JKAMP,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,STAU2,OGA,FYN,ZNF274,KIAA1841,GATM,MSTN,SESN1,FREM1,MALT1,COPS8,TNRC6A,FERMT2,GRIA2,FAM19A2,PSIP1,MAP4K5,RASSF8,MIER3,HLF,NEGR1,AGFG1,ZNF181,TJAP1,IL12A,SLC35G1,KCND2,KCNJ16,KIF5A,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LRP1B,MEST,POC1B,MYCN,CNOT4,NOVA1,NPTX1,SMIM11A,NTRK2,NUCB2,IGSF11,P2RY1,CNTN3,PCDH8,PRTG,GPR85,GNG2,SERPINI1,NALCN,FAM218A,SNX10,XRN1,KCTD15,PLCL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SNRK,CNTLN,PTCH1,BDNF-AS,MTMR10,TMEM260,PTPN13,PTPRD,EML5,ZSCAN2,FAT4,OXR1,RADX,MSANTD2,RDX,RET,REV3L,ERI2,FIGN,SLC25A36,NUDT11,RNASEL,CCDC82,ZNF532,CARF,ROBO1,RORB,CCDC102B,RPE,ARMH4,FBXW7,KIAA0895L,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,SEMA6D,SCN8A,SCP2,SUPT20H,KIF21A,SHC4,AMBRA1,FNDC3A,R3HDM2,SEC31A,ANKRD6,FAM81A,KDM4D,SLC12A2,SLC14A1,ZFP1,ZNF667,MYH15,SNAP25,MBD5,KIF13A,SNRPN,FAM219A,PDZD2,BDP1,DOK5,KDM3A,KDM4C,ZNF423,SPART,CLASP2,TROVE2,POGZ,ITPRID2,ZNF302,MPRIP,SEPT8,RGL1,DIP2A,PHLDB1,KANK1,ZC3H4,SYNE2,VPS13A,SYT1,ANKRD28,ADGRL3,TBCEL,SATB2,ZEB1,CLASP1,PUM2,SLC35G2,CCDC173,RNF216P1,ZFPM2,ASXL3,ERCC6L2,CSMD1,TRIO,RUNDC3B,AMACR,TUBB2A,FAM155A,UGT8,VLDLR,TBC1D15,RBFOX3,WIPF1,CLIP2,CLDND1,GUSBP1,XRCC4,ZNF23,TRIM9,MKRN3,LYPD6,ZBTB38,REEP1,TFIP11,SMARCAD1,EMSY,EVI5,TMEM178A,NAV3,FAM13C,KAT6A,PHTF2,NLRP3,RNF170,KLHDC1,FXR1,IFT88,GAN" MicroRNA hsa-miR-3120:mirSVR_highEffct hsa-miR-3120:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-139 1.22E-135 5.80E-137 5.34E-136 350 1969 "RALGAPA1,ABCF1,KCNH8,PWWP2A,RNF150,ESYT2,ZNF608,INTS2,KLHL13,PCDH19,AGT,HACE1,OSBPL1A,TBC1D14,TAOK1,ADGRF5,C1QTNF3,ALCAM,ARHGAP20,PCDH10,FAM135A,GPRASP2,AMPD2,OGT,CDC42BPA,ANK2,APC,IGDCC4,ZFYVE28,PDE8B,NUMB,TMEM108,ATP1B3,RNF182,CFLAR,DST,SYNJ1,ARHGEF7,MYRF,CA8,KALRN,RUNX1T1,NFS1,LDB2,KRIT1,SEPT7,ZBED1,MAGI1,SRSF11,CHN2,TAOK2,NRXN3,PLAA,CLTC,QKI,HECTD1,CNTFR,IQCK,ARMC8,AKAP6,MAGED1,TBPL1,AHCTF1,ZFP28,IGDCC3,SLC35F1,CPS1,FAM171B,CREM,HAPLN1,NCOR1,LRIG1,CSNK1G3,VAC14-AS1,FAM169A,GREB1,ZSCAN23,CCDC144A,DOCK4,HDAC9,ARHGAP32,TCAF1,ARHGAP24,HDAC4,KIAA0586,PITPNC1,SPATA2,ELMSAN1,MYEF2,C2CD2L,ZC3H11A,RHOBTB1,SACS,DMD,DYNC1I1,CPEB2,DOCK2,DPP6,DTNA,ECM2,FAM78B,DNAJB6,ABCC5,AASDH,HIPK3,EGFR,KMT5B,IRAK4,EMX2,COQ7,SPEG,ETV1,TUBB3,CHST15,MED12L,FGFR1,FGFR3,TMEM164,MAD2L2,FHL1,POLK,SYNCRIP,IQCG,FLT1,SLC37A3,SYT3,NBEA,TMEM107,SMC2,HVCN1,UFM1,ATP2C1,CELF1,CSPG5,SARAF,AP4B1,ZMAT1,GABRG2,DISC1,KIAA1841,IGSF5,GDF9,ADAM28,MMADHC,COPS8,SPIN1,GLI2,TOX3,MSL3,HTATSF1,GNAO1,GPD2,TDRKH,STON1,LPAR4,PCLO,CNTRL,GRIA2,PLCD4,CIT,RNF165,RABL2A,HNF4G,SMAP1,ZNF546,INPP1,NME9,JAK2,KCNH2,KCNJ5,IPO5,STXBP5,LAMP2,STMN1,HECTD2,PACRG,SMAD1,PIK3AP1,MAP2,MAPT,MARK3,MBNL1,LRP1B,MKLN1,AFF1,ZNF680,MSR1,MYO9A,HNRNPM,NCAM2,NOVA1,NRCAM,NTRK2,CLDN11,GLIPR1L2,PCDH9,PDE1C,PDE4B,ENPP2,GNG2,PFKFB2,OLA1,NALCN,PIK3C2A,PCDH18,SMIM7,EPB41L4B,PPM1B,PPP2R5E,PRKACB,PRKCB,CNNM2,SNRK,WDR25,PIGG,MTMR10,PTPRD,C1orf109,PPP2R3C,TMEM255A,USP47,RAP1GDS1,RASGRF1,RBBP6,RADX,RDX,ZMAT4,FIGN,SLC25A36,NUDT11,ZFHX4,LGI2,ZNF532,SETD5,C12orf49,ELP2,CCDC102B,KCNIP3,KCNIP1,AP1AR,RMI1,SALL1,FNIP1,COPZ1,KIF21A,SH3GL3,HKDC1,FBXO11,FNDC3A,CNKSR2,NLGN1,DHX30,CCDC88A,SLC11A1,CDK5RAP2,SNCA,RBM34,PDZD2,TRERF1,SOX3,PEG10,SPTAN1,ZBTB43,ITPRID2,SAMSN1,ERBIN,ST5,MPRIP,SEPT8,CEP68,SEPT3,KLHL7,VPS13A,SYP,SYPL1,PJA1,ADGRL3,TBCEL,TBL1X,SATB2,TPCN2,USP22,PCDHGA11,SYNE1,SLC19A3,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,VWCE,ZFPM2,C18orf54,AP4E1,ARL10,THRA,BHLHB9,ERCC6L2,TMPO,CSMD1,PIK3R5,TRO,TSN,ANKRD20A2,CA14,TSC1,SSBP2,TST,SGK3,PLEKHH2,P2RY12,WRN,KLC2,CLDND1,RICTOR,ZIC1,ZNF708,ELFN1,NDRG4,MKRN3,ZNF142,ZBTB38,TMEM237,ZNF184,SPIRE1,ZFAND5,SMARCAD1,EMSY,ADAMTS9,TMEM178A,CIAPIN1,NAV3,KCNAB1,ITM2C,MPPE1,MRPL47,DOCK8,UBE3B,KAT6A,PHTF2,ADAMTSL3,RSPRY1,NETO1,RNF146,FAM198A,JPH3" MicroRNA hsa-miR-330-3p:mirSVR_highEffct hsa-miR-330-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.50E-139 2.52E-135 1.14E-136 1.05E-135 341 1871 "ACADM,CLK4,KLHL32,CCDC85A,GALNT13,UNC5A,RNF150,DPY19L2P4,ZNF608,SMIM17,ARHGAP20,PCDH10,GPRASP2,AMPH,OGT,DPP10,LCORL,MAP4K3,LGR5,MADD,IGDCC4,ARNTL,CADPS,CDK13,ZBTB10,RASL11B,TMEM108,ATP2B2,ZNF583,SLC2A11,BACH1,ADGRB3,BBS2,KSR1,DST,FUBP1,SCAPER,JAZF1,MYRF,IL33,CALM1,PTBP2,SLC25A14,VXN,CAST,CBR1,KRIT1,CERS5,USP6,USP2,C1orf52,MAGI1,CDO1,TIGD7,CCPG1,SRSF11,CHN2,SLIT2,NRXN3,CLCN3,MAP4K4,CNN3,ARMC8,COL4A5,ABI3BP,MYRIP,CNRIP1,CPS1,CREM,NCOR1,GDA,ARHGEF10,OSBPL3,CSNK1G3,APPL1,DCAF4,DOCK4,GPRASP1,ZFYVE16,ZNF337,LIN54,KCTD8,MAML1,GIT2,YTHDC1,MYEF2,ELMO1,FBXL5,KIAA0319,RHOBTB1,SPOCK3,SGSM2,WDR20,FAM107B,KIF19,DLX1,DMD,DMTF1,DPP6,DRP2,RCAN1,DNAJB6,DNM1L,EDN1,EDNRA,ANKRD46,PHF20L1,APH1A,MBNL2,ING4,TUBD1,VPS13B,EPB41L2,RCAN2,GPHN,RABEPK,F5,FAM198B,ACSL4,FCGR3A,PPP1R1B,FGF12,FGFR1,FHL1,SUCO,IP6K2,AGAP2,SYNCRIP,SEMA4D,ANKFY1,SLC37A3,JKAMP,TMEM107,ATP2C1,ERGIC3,CELF1,ST6GALNAC3,NSG1,STAU2,TVP23A,FYB1,ERAP1,KIAA1841,GCNT2,SULT1C4,GGT7,TCERG1,COPS8,DBF4,GLYR1,GPR75,TOX3,MSL3,KDM2B,LUZP2,KCNMB4,GNAO1,TDRKH,FUT10,GPR37,GRB10,MIER3,HSF2,LRRC75A,IRF8,NKD1,RBPJ,SCIN,ZNF678,CREG2,KIF2A,LIG4,LMO2,SYTL4,NCOA7,ASPRV1,PACRG,MAP4,MARK1,MAT2A,MBD1,MBNL1,LRP1B,MKLN1,AFDN,XRRA1,MN1,COL28A1,MSI1,BLOC1S2,MYH3,NF1,NPTX2,NTRK3,PCDH9,PDE1B,SERPINI1,PIK3R1,SNX10,PRIMPOL,PMP22,STRN3,LRP12,ING3,SH3KBP1,MINDY2,PPM1B,PPP2R5E,KANSL1,PRKACB,CEP41,MAPK9,MAPK10,HYDIN,DIRAS2,VPS13C,GDPD2,ELOVL2,PTK2,ZIK1,PTPRB,C1orf109,MARCH1,CEP97,USP47,RAD51D,RASGRF2,ZDHHC14,GTDC1,NUDT11,PBRM1,ZFHX4,CCDC82,ROBO1,ELP2,RPL15,MCMBP,ADAL,KCNIP3,ZNF568,CCDC112,FAM192A,RMI1,S100B,SALL1,MAPK12,SEMA6D,SATB1,SCP2,GALNT10,KIF16B,SHC4,CHD9,FNDC3A,ST6GAL1,CNKSR2,SYBU,DHX30,CCDC88A,NAPB,COA1,MBD5,PDZRN3,USP33,KDM3A,SP4,KDM4C,ZNF423,ZC3H13,SPART,ATP10B,TROVE2,POGZ,SSTR1,ERBIN,STAU1,ZSCAN29,DIP2A,SULF2,SYNE2,COBL,TACC1,DNMBP,FBXW11,ATMIN,TCF4,TRIM2,CLASP1,DOCK9,SLC19A3,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,SIRT1,ITGB3BP,TK2,ASXL3,BHLHB9,FAM124A,KAT6B,CABIN1,C9orf85,SYNPO2,ELP5,TRPS1,TSC1,CLHC1,CLEC2L,PLEKHH2,USP1,VLDLR,KLC2,CFAP298,ZNF711,MICU3,KCNT2,MKRN3,ANKS1B,EMSY,PRTFDC1,LINC02210,PRDM8,RNF103,TUBA1A,ADAMTS9,MDH1B,ITM2C,PLSCR4,FAM13C,FZD3,DOCK8,ACTR3B,RNF170,MSRB3,FAM198A" MicroRNA hsa-miR-659:mirSVR_lowEffct hsa-miR-659:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.58E-136 5.36E-132 2.33E-133 2.15E-132 338 1883 "ACADM,NCKAP5,ACTN1,FMNL2,TMEM132B,ADCY6,TMCC3,ADD2,USP31,BEND6,DPY19L2P4,MTUS1,KLHL13,KCTD16,KIAA1324,WDR35,CEP126,FAM135A,SYT13,AMPD2,AMPD3,DPP10,CCDC146,ARMC12,MAP4K3,TNRC6C,LGR5,ARNTL,CDK13,CCAR2,EIF4G3,SLC2A11,DPY19L3,MPDZ,CFLAR,BMPR1B,ST3GAL5,NAE1,JAZF1,GPC2,CA12,CACNA1A,CACNA2D1,CACNB4,CALB1,CAPN3,CH25H,PRC1,CLDN10,KYAT1,KRIT1,SLC16A4,ENTPD6,ARHGEF2,EVI5L,DLGAP2,CDO1,NUMBL,SRSF11,FOXN3,EPS15L1,PPT2,NGEF,C4orf33,SULT4A1,PCYT1B,AKAP6,LETMD1,ABI3BP,AHCTF1,SMARCAL1,SEC31B,CREM,RBM39,CRHBP,CRMP1,SNCAIP,RGS6,LRRC3B,OSBPL3,SUSD5,VCAN,CST3,PITPNM3,PNPLA8,RIMS2,ZSCAN23,RUBCN,ARHGAP32,MATR3,DGKB,DAPK1,SCRN1,GIT2,ARMCX2,MFAP3L,ZC3H11A,POM121,RHOBTB1,PLPPR4,SNAP91,SV2B,SPOCK3,EXOG,USP3,NR1D2,DOCK2,DPYSL2,SLC25A18,ECM2,GOLT1B,AASDH,EDNRB,RASGRP1,KLHL5,PHF20L1,COPS4,PLEKHA1,TNK2,MRNIP,C8orf37,EPB41,GPHN,RABEPK,STX2,SRRM1,MRPL37,MRPL10,ACSL4,PTK2B,TAOK3,ST3GAL6,CHST15,FER,OLFM1,FGF13,FHL1,POLK,SUCO,HPCAL4,SYNCRIP,FLT1,EFCAB2,HVCN1,UFM1,PDLIM5,FAM49B,ATP6V1H,ERGIC3,CELF1,ST6GALNAC3,MSANTD4,OGA,MEGF11,MEGF10,GABRG2,GALC,RAPGEF6,ERAP1,SRRM4,GATM,ZNF276,GLI2,GLYR1,ZNF638,LUZP2,DCLK2,GRIN2D,PRDM5,CIT,BVES,AP4S1,PSIP1,RNFT2,ADAMTS6,FRMD3,HNF4G,ZNF491,HSF2,SOWAHA,NKD1,RBPJ,NIM1K,IL6ST,ZNF678,NME9,SLC35G1,STXBP5,STMN1,LMO2,PIK3AP1,MAN2A2,AQP11,MBNL1,POC1B,MITF,ADAM22,MSR1,PTOV1,MXI1,LYRM9,MYT1,TCEAL5,ZC3H12B,NDP,IDNK,NEFH,NF1,NFE2L2,NFIX,PCBP3,CHAMP1,CLDN11,ZNF713,GLIPR1L2,PCDH9,PCSK5,CDK18,ENPP2,GNG2,PIK3R1,RETREG1,PLCB2,PLEC,PLIN1,LRP12,ING3,RETREG2,FA2H,POLG,PPM1B,LRRN3,PKIA,GRAMD1C,CNNM2,CNTLN,BDNF-AS,PTPN13,PTPRD,PEX2,TTC13,CEP97,SUSD4,RAP1GDS1,ENOX1,RASGRF2,RFX2,RIC8B,RNASEL,ALG9,PNMA8A,KIRREL1,CCDC25,SPIN3,ATP8B4,HUNK,KCNIP1,ZNF354C,AP1AR,ATXN7,SCN8A,SCP2,PEAR1,SH3BGR,KIF21A,ARX,FERMT1,AMBRA1,FBXO11,ANKRD6,SLC6A8,KDM4D,CCDC88A,SLC12A2,SLC14A1,NAPB,ATF7IP,SLC22A4,TET1,SMARCA4,MBD5,KIF13A,SNRPN,DOP1A,HECW1,TEX2,PEG10,LHPP,SSTR2,SS18,STAU1,SEPT8,ADHFE1,SYNE2,NUDT10,TCF4,SIN3B,SATB2,CUX2,RPGRIP1L,SZT2,SLC19A3,OBSL1,NSD1,RNF216P1,FAM200B,PMS2CL,GPR161,AKTIP,NR2E1,TPM2,DOK6,SYNPO2,PDSS1,TRO,DCBLD1,SSBP2,TTTY15,FAM155A,VLDLR,ZBTB14,ZNF45,ZNF154,FSTL5,EML6,ANKS1B,ZNF213,MFF,CADM2,GAL3ST3,SLC17A7,KCNAB1,ITM2C,CASC15,TIGD6,RNF170,CPNE4,FAM198A" MicroRNA hsa-miR-301b:mirSVR_highEffct hsa-miR-301b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.96E-135 1.09E-131 4.56E-133 4.20E-132 314 1621 "RALGAPA1,CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,BEND6,DPY19L2P4,HECW2,KLHL13,OSBPL1A,WDR35,HFM1,SPARCL1,ALCAM,SRPX,FAM135A,LRCH2,LCORL,APAF1,APC,LINC00173,STK33,NCOA1,STX16,ZNF582,ZNF583,N4BP2L1,DPY19L3,ADAM23,TTLL9,BACH1,ADGRB3,NRP2,DST,SYNJ2,C5,CALB1,CABP7,THSD7A,KALRN,CAST,RUNX1T1,USP6,SEPT7,TIGD7,CCPG1,CFL2,PLAA,CLTC,SRP14-AS1,FHL5,AKAP7,ARMC8,FAM149A,RCHY1,CLOCK,CREM,RNF14,GDA,CSF1,LRIG1,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,HDAC9,DCAF8,LONRF1,SPATA2,YTHDC1,ELMSAN1,FBXL5,DDX46,RHOBTB1,SPOCK3,WDR20,RAB39B,DYNC1I1,CPEB2,DPYSL2,DNAJB6,ABCC5,DNM1L,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,KMT5B,EGR3,ASB3,CERCAM,PAN3,RCAN2,ENPP6,RABEPK,TLR7,RASL12,ABCA8,ACSL4,GORAB,MED12L,FGF11,FGF13,FGF14,SEC23B,FOXF2,SYNCRIP,RGPD5,ATP13A4,FLT1,COQ5,JKAMP,NBEA,MEGF10,B4GALNT1,ZNF274,ERAP1,ARFIP1,SESN1,ADAM28,DBF4,RAB30,TNRC6A,KDM2B,MAP7D2,LUZP2,RAB40B,GPD2,PRUNE2,GRB10,GRIA2,SERP2,ZNF496,CIT,RNF165,HNF4G,HNMT,IRF8,MSL1,ZIC5,LRRCC1,ZNF678,CDH20,KCNN3,CREG2,IPO5,TTYH2,LIG4,LIMS1,MAP4,MATN3,MBNL1,MEIS2,LYRM9,ZNF862,MYT1,NELL2,NFE2L2,CNOT4,OCRL,OPA1,P2RX7,GPR137C,DPY19L2P2,PCDH9,PCSK5,PDE1C,PFKFB2,DUSP26,SERPINI1,CCSER2,JAKMIP1,PURG,MAPKAP1,LRP12,PPP1R1A,PPP2R5E,PPP3CA,KANSL1,PRKACB,PSD,MTMR10,STK32A,EML5,PTPRG,ZSCAN2,PID1,CEP97,RAD17,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,UBR7,SLC25A36,KLHDC8A,CARF,ROBO2,EPHA10,BAALC,LRRK2,CLIP1,RTN1,ZNF354C,CCDC112,DGLUCY,LRFN5,TNFRSF19,PEAR1,KIF21A,ARX,KIF16B,CHD9,FBXO11,SYBU,BTBD3,WDR47,KANSL3,SEPHS1,SLC8A1,CCDC88A,SLC14A1,BTBD7,ZNF667,SNAP25,KIF13A,USP33,TRERF1,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,FBXW11,ATMIN,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,SLC44A1,BHLHB9,ERCC6L2,R3HDM1,CSMD1,TNS1,STXBP4,TSC1,UBC,RPL7L1,FAM155A,CCDC14,WRN,ZNF711,TRIM9,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,SMARCAD1,UPF3A,MAP3K12,MFF,STOX2,KCNAB1,WNK3,PLSCR4,RGS7BP,DNAH10,UBE3B,NHSL1,FXR1,FRMD6" MicroRNA hsa-miR-1299:mirSVR_highEffct hsa-miR-1299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-135 1.47E-131 5.88E-133 5.41E-132 340 1912 "KCNH8,CLK4,TMEM132B,ADCY6,KIAA1211,AP2A2,KLHL13,WDR35,TXNDC16,C1QTNF1,SPOP,BBOX1,DPP10,CCDC146,PARG,APBA2,APLP1,UPRT,LGR5,PLA2G4C,CDK13,MARCH3,CCDC74A,NUMB,ATP1B3,ATP2A2,ZNF582,SLC2A11,RNF182,ADAM23,RGS9,NRP2,BID,CFLAR,PROM1,DST,SYNJ2,ARHGEF7,MTMR2,CA8,KALRN,CAST,SPAG9,CBR1,CD86,CBFA2T2,ZMYM4,MAGI1,NUMBL,CFL2,NDST3,PLAA,CLCN3,TPP1,CLTC,NGEF,C4orf33,FHL5,AKAP6,SLC4A8,RCHY1,SMARCAL1,TOGARAM2,MYRIP,IGDCC3,SLC35F1,CRMP1,GDA,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,CNTNAP2,UBXN2A,PHF14,PNPLA8,CTH,PUM1,CYBB,BOC,DOCK4,RIPOR2,IST1,DGKB,DDX46,RHOBTB1,HS3ST2,DNAH9,CD99L2,DNM1L,E2F6,AASDH,EDN1,ANKRD46,CNNM1,TMTC1,YAF2,FAM13A,PHF20L1,MRO,MBNL2,AASS,EIF5,PLEKHA1,TNK2,TMEM35A,EMX2,EPB41L2,RCAN2,RASGRP2,EPHB1,ENPP6,RABEPK,STX2,ERCC2,NCALD,CEP85L,VPS26C,ADGRV1,FER,FHL1,SUCO,SEMA4D,ATP13A4,ANKFY1,NELFCD,EFCAB2,ZNF605,ST6GALNAC3,MSANTD4,TVP23A,HRASLS5,GALC,TMEM8B,MTHFD2,DISC1,LRRC37A6P,GATM,ALDH1L1,GCNT2,MSTN,GGT7,TCERG1,ZNF638,LUZP2,WDFY3-AS2,GPR12,ATP2B1-AS1,GRIA2,ZNF496,RABL2A,PSIP1,RNFT2,GUCY1B1,MIER3,SYNPO,ZDHHC15,LRRC75A,IRF8,IL6ST,ITGAM,KCND1,KPNA5,STXBP5,TTYH2,HECTD2,NCOA7,LSS,PIK3AP1,MAP6,MAT2A,MEF2C,MEIS2,MEST,KCTD6,MMP16,MX1,NF1,CNOT4,PCBP3,NTRK2,NUCB2,IGSF11,CHAMP1,OPA1,CLDN11,PCSK1,PDE4D,GNG2,PFKFB2,OLA1,SERPINI1,CCSER2,XRN1,SLC25A23,SMIM7,TRHDE,LRP12,EXOSC10,EPB41L4B,PPP2R5E,RANBP3L,CEP41,PRKCB,HYDIN,GDPD1,MASP1,VPS13C,PTK2,ZIK1,PTPRG,C1orf109,ZSCAN2,ZNF615,SLC25A48,FAM66C,OXR1,RDX,ZMAT4,GTDC1,PBRM1,SUGCT,C12orf49,CARF,ELP2,NEK11,SPIN3,ATP8B4,RPS6KA2,MAP6D1,KCNIP1,ZNF568,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,SCP2,TNFRSF19,SH3BGR,ARX,CHD9,FNDC3A,FHOD3,NLGN1,NUBPL,WDR37,SLC2A5,SLC6A11,KDM4D,CCDC88A,SLC11A1,SLC22A4,CXXC4,CDK5RAP2,RCOR3,LIMCH1,SNAP25,KIF13A,LMBRD1,FNBP1,SP4,GLT8D1,ZC3H13,CLASP2,CLSTN2,POGZ,ITPRID2,NKAIN2,STAU1,CEP68,DIP2A,ADHFE1,ZC3H4,PRRC2C,COBL,ANKRD28,TACC1,TACR1,ANKRD12,MCF2L,DNMBP,TBCEL,TPCN2,TCF12,USP22,CLASP1,SYNE1,OBSL1,FRYL,CCDC173,DICER1,ZFPM2,CHST8,AP4E1,GPR161,ZNF34,SLC44A1,TIAM1,ACTR6,ERCC6L2,TMPO,RIMBP2,SYNPO2,DCBLD1,TSN,RPL7L1,SLC35A4,UBE3A,UGT8,PLPPR2,CCDC14,CFAP298,ZBTB14,ZIC1,TRIM9,AGMO,NDRG4,CELF4,ZBTB38,SMARCAD1,UPF3A,SLC30A4,MFF,NAV3,KCNAB1,WNK3,EPM2A,HRASLS,ST7,HNRNPA3,PHTF2,FBXO36,CASC15,TRAM2-AS1,RNF170,MSRB3,FXR1,FRMD6,FAM198A" MicroRNA hsa-miR-301b:mirSVR_lowEffct hsa-miR-301b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.73E-135 4.89E-131 1.88E-132 1.73E-131 331 1817 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,PWWP2A,PTCHD1,PCDH19,KCTD16,CC2D2A,AK2,ADGRF5,ABCD2,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,PHF12,EPB41L5,TNRC6C,IGDCC4,SLC4A4,ATP2A2,DOCK11,KSR1,BMPR1B,FUBP1,MTMR3,SGCE,LDLRAD4,CAMK2G,USP2,CBFA2T2,MAGI1,NOG,CACNA2D2,SRSF11,MS4A7,FBXO7,C4orf33,QKI,HECTD1,CNN3,CNR1,IQCK,AKAP5,SLC4A8,TBPL1,BAG4,ZNF521,HAPLN1,SUSD5,SIPA1L1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,LIN54,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KIAA0319,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,USP3,DNAH9,MED12,NR1D2,SLC25A18,DRP2,DTNA,ECM2,E2F5,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPB41,GPHN,CEP85L,KATNAL1,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FDFT1,FECH,OLFM1,TMEM164,AMOTL2,PRKAG2,POLK,MEX3B,PCYOX1,ANKFY1,NOP56,STAU2,GABRA3,ZNF44,GABRG1,FAM120B,GALC,RAPGEF6,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,TOX3,CBX1,FERMT2,GPT2,ADGRA3,MCHR1,GPER1,PCLO,GRM2,LINC01089,KAT7,SOX21,ADAMTS6,GUCY1A1,MAP4K5,ATOH8,FAM222A,RASSF8,HAS2,FRMD3,MIER3,HLF,SYNPO,AGFG1,IGF1,NIM1K,NME9,SLC35G1,KCNN2,KIT,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LRP1B,MEIS1,AFF1,AFDN,ZNF680,ADAM22,MYCN,MYO9A,IDNK,NF1,NOVA1,NPTX1,NPTX2,TBC1D25,GLIPR1L2,PDE4B,PDE4D,GNG2,CYTL1,PFKFB3,PIK3C2A,TMIE,PIK3R1,ZFYVE21,FAM216A,PDZRN4,STRN3,SCHIP1,ING3,POU6F1,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,SNRK,ZIK1,PTPRD,PTPRE,TMEM231,PPP2R3C,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,FIGN,RFX3,RIC8B,RNASEL,CCDC82,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,RYR3,ZNF331,FAM192A,SATB1,SCN8A,GALNT10,FOXRED1,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,FAM81A,SLC12A2,CPEB4,MAST1,SMARCD3,RCOR3,CABCOCO1,SNRPN,FNBP1,KDM3A,ZSWIM8,KDM4C,TSPYL2,RBM26,LMO3,LARP4,STAU1,SEPT8,DIP2A,ADHFE1,STXBP1,SYT1,SLC37A2,TACC1,TACR1,EXOC7,PDLIM2,AGTPBP1,TBCEL,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,SYNE1,DOCK9,PCDHB7,USP32P1,FRYL,RIMBP2,PARD3,NPL,NR2C2,ZNF346,SMUG1,TRPS1,HIRA,EIF4ENIF1,UBE3A,LINC00689,TOM1L2,VLDLR,P2RY12,CLDND1,XRCC4,PCDH20,ZNF24,CELF4,SPIRE1,EMSY,SLC38A1,EVI5,LINC02210,PRDM10,RNF103,NAV3,FIP1L1,FAM47E,PDSS2,FAM13C,AMN1,DOCK8,RTN4,PHTF2,FBXO36,GJC2,CASC15,FAM219B,JMJD1C,RNF170,NETO2,SOCS4,CPNE4,JPH3" MicroRNA hsa-miR-199b-5p:mirSVR_lowEffct hsa-miR-199b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.82E-134 1.02E-130 3.78E-132 3.48E-131 333 1844 "DGCR6,ABR,ACHE,ABHD6,KDM5D,TMEM132B,PLEKHH1,USP31,RNF150,BEND6,SLC24A4,AP2A2,KCTD16,HACE1,TBC1D14,OSBPL8,CC2D2A,TAOK1,SEMA6A,ALCAM,ABCD2,ARHGAP20,SYT13,AMPD3,ANK2,SUGT1P4-STRA6LP-CCDC180,UPRT,CDK10,TMEFF1,ARRB2,CADPS,MARK4,CCAR2,ATP1B3,ZNF582,DPY19L3,ATP6V0A1,TTLL9,ADAM15,BACH1,ADGRB2,BBS2,BCHE,BID,PROM1,KSR1,SYNJ1,ARHGEF7,MTMR2,RAB29,WASF1,MYRF,CA8,CACNB4,CALB1,PTBP2,CAMK2B,CH25H,PRC1,CBLN1,ZNF501,METTL6,LRBA,CDH2,LOC730101,DLGAP1,CLGN,CBARP,RAB33A,PPT2,ABCG2,SULT4A1,SRP14-AS1,HECTD1,AKAP7,AKAP6,COL9A1,MYRIP,ZNF385A,SLC35F1,CREM,SEC24C,ARHGEF10,PDE4DIP,RASGEF1C,SLITRK5,KIAA0040,GREB1,PUM1,DCAF4,BOC,DCAF8,INTS1,IP6K1,BRINP1,ARMCX4,HEPH,ZC3H11A,DDX46,PLPPR4,SNAP91,DMD,DNM1,DNAH9,NR1D2,SLC12A6,DPP6,DPYSL2,DRP2,ABCC5,E2F5,EDIL3,EDNRA,EDNRB,HEYL,FRY,YAF2,SUGP2,KMT5B,EIF4G2,IRAK4,LRRC17,DNAJC27,F5,CLVS1,FCGR1A,FCGRT,KAT8,ZNF589,FGF11,PRKAG2,SUCO,MEX3B,PCYOX1,ANKFY1,AKAP3,JKAMP,CINP,TPK1,ZNF605,ERGIC3,AP4B1,OGA,MEGF10,ZNF274,IP6K3,DISC1,SRRM4,KIAA1841,GATM,ALDH1L1,MSTN,WASHC2A,SESN1,MMADHC,USP19,GGT7,MALT1,TCERG1,COPS8,MAP7D2,GRB10,IRAK3,NCKAP1L,MIER3,HLF,VSIG4,ELOVL5,HNMT,NEGR1,ICA1,ZNF546,GAREM2,SCIN,KTN1,STMN1,HECTD2,MAP2,MAP4,MATN2,PPM1L,POC1B,MITF,AFF1,MN1,MPP2,MYCN,MYO9A,RTL5,NEFM,NEFH,NEK1,NOVA1,SLC11A2,NTRK3,IGSF11,OCRL,GLIPR1L2,PDE3A,PDE4D,ENPP2,TMOD2,PIK3R1,FAM218A,GPSM2,SLC25A23,PLXNB1,PURG,PMP22,ING3,SH3KBP1,FSD1,POU6F1,PPM1B,RASGEF1B,PRKCB,EPDR1,MAPK7,MAPK9,GRAMD1C,TMEM104,WDR25,CNTLN,PTK2,STK32A,PTPRD,PTPRE,PTPRG,PTX3,ZNF615,PPP2R3C,TMEM255A,FAM66C,FAM184A,ROGDI,RASGRF1,MORC4,GTDC1,RFX3,SLC25A36,PBRM1,SUGCT,CARF,CCDC25,RPL15,MAP6D1,RPS20,TRAPPC13,DGLUCY,ATXN7,TNFRSF19,FBXO11,FNDC3A,R3HDM2,ST6GAL1,CNKSR2,SLC2A5,BTBD3,ZNF430,SLC12A2,NAPB,ELMO2,INAVA,MAPKBP1,SNRPN,FAM126B,MYO16,PDZD2,SP4,MYCBP2,KDM4C,PEG10,SPTB,ATP10B,CEP68,VPS13A,TMEM150C,ARC,SYN2,SYPL1,TACC1,TAL1,FAM208A,FBXW11,KLHL4,ZFP90,TPCN2,TRIM2,DOCK9,FAM189A1,SLC19A3,HIF3A,TEK,AP4E1,SLC44A1,MTMR14,TMEM9,BEX4,TPM1,RGMB,PDSS1,STXBP4,TRPS1,TTC3,SGK3,FAM155A,ZNF709,LAT2,ZNF781,GUSBP1,CFAP298,ZNF24,ZNF28,ZNF70,NDRG4,MKRN3,CELF4,SMARCAD1,UPF3A,SLC30A4,MAP3K12,SLC38A1,GDPD5,LINC02210,PRDM10,RNF103,RGS7BP,FZD3,ADAMTSL3,JMJD1C,FXR1,NETO2,JPH3" MicroRNA hsa-miR-802:mirSVR_highEffct hsa-miR-802:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-133 2.38E-129 8.51E-131 7.83E-130 339 1932 "CLK4,NDRG3,FMNL2,KLHL32,CCDC85A,AXIN2,PWWP2A,KIAA1211,DPY19L2P4,PCDH19,TBC1D14,OSBPL8,HFM1,ALCAM,CEP126,FAM135A,AMPD3,DPP10,EP400,APC,LGR5,ZFYVE28,STK33,ZBTB10,TMEM108,ATP1A1,ATP1B3,ATP2B2,N4BP2L1,BACH1,BBS2,MPDZ,SEC11C,NRP2,CFLAR,DST,SGCE,WASF1,CA8,CACNA1B,PTBP2,CAMK2A,SLC25A14,KRIT1,USP6,ZBED1,L3MBTL4,CFL2,SRSF11,CHN1,LHX2,CLTB,SULT4A1,HECTD1,CNN3,ARHGEF6,AKAP7,ARMC8,AHCTF1,BAG4,ZNF521,IGDCC3,CPS1,FAM171B,SEC31B,ENTPD4,CRMP1,ANKRD44,GDA,CSNK1G3,PDE4DIP,PPP1R16B,ERC2,UBXN2A,PHF14,PUM1,RUBCN,CCDC144A,HDAC9,KATNAL2,ZFYVE16,MATR3,KCTD8,DGKB,DBI,ZNF804A,FBXL5,SNAP91,SGSM2,WDR20,RAB39B,CPEB2,DMTF1,DPP6,PDCD6IP,ECM2,ABCC5,DNM1L,E2F5,EDN1,EDNRA,ANKRD46,RASGRP1,KLHL5,FRY,YAF2,CELSR3,PHF20L1,MBNL2,KMT5B,GOLGA7,ASB3,RGS17,PAN3,DCTN4,USPL1,EPB41,EXTL2,F5,CLVS1,FAM198B,ZNF585B,SCML2,RACK1,GORAB,FGF1,FGF14,TMEM164,SCARA3,MEX3B,SEC23B,ATP13A4,SMC2,UFM1,ATP6V1H,STAU2,MSANTD4,OGA,NEURL4,GAD1,ZNF274,IQGAP2,MTHFD2,C15orf41,DISC1,KIAA1841,MSTN,PPARGC1A,BRD8,TCERG1,DBF4,TNRC6A,ZNF638,RAB40B,ADGRA3,GPD2,PRUNE2,TDRKH,LPAR4,DIDO1,GRM8,CIT,GSTT2,PSIP1,GUCY1B1,RASSF8,MIER3,VSIG4,ZNF491,SMAP1,SOWAHA,NKD1,RBPJ,TJAP1,SCIN,ZNF678,FAM69A,KCNB1,KCNN2,CAMK2N2,STMN1,PAXBP1,HECTD2,NCOA7,LSS,LYPLAL1,AQP11,MATN2,MEST,PPM1L,ZNF680,BLOC1S2,THYN1,MXI1,P2RY13,NRCAM,SMIM11A,SETD4,CHAMP1,GLIPR1L2,PCDH9,SLC10A4,NLGN3,SNX10,KCTD15,FAM216A,PLIN1,PCDH18,MAPKAP1,STRN3,SCHIP1,MINDY2,PPP2R5E,PPP3CA,PRKAB2,PRKACB,PKIA,MAPK9,HYDIN,SAMD9,VPS13C,PTCH1,PTK2,PTPN13,PTPRE,PTPRG,PTPRO,PTX3,ZSCAN2,CEP97,TMEM255A,ACSS3,FAT4,FAM184A,OXR1,RADX,KHDRBS2,REV3L,FIGN,UBR7,NUDT11,RNASEL,ZFHX4,ALG9,ELP2,MAP6D1,LRRK2,RPS20,RTN1,TRAPPC13,AP1AR,SATB1,ATXN7,CASC3,SGK1,CPEB3,NLGN1,NUBPL,WDR37,FAM81A,EPN2,KANSL3,SLC8A1,CCDC88A,SLC12A2,SLC14A1,NAPB,BTBD7,ZNF667,CDK5RAP2,ANKRD36,MAPKBP1,SNRPN,PDZD2,SP2,MYCBP2,NFASC,CLASP2,TROVE2,ELOVL4,DIP2A,SEPT3,VPS13A,C12orf76,MTCL1,PJA1,FAM208A,ADGRL3,KIAA1107,AGTPBP1,TBCEL,FBXW11,TCEA1,TCF4,DMXL2,SATB2,TRIM2,RPGRIP1L,USP22,SYNE1,PCDHB15,PCDHB6,PUM2,TEK,FAM200B,DICER1,ZFPM2,CDH22,SLC44A1,ERCC6L2,KAT6B,TPM2,C9orf85,NEIL2,PPIL6,ANKRD20A2,TSC1,RPL7L1,UBE3A,UBTF,VLDLR,ZNF781,WRN,RICTOR,ZFP37,ZIC2,ZNF711,MICU3,LYPD6,STOX2,ADAMTS9,KCNAB1,FAM47E,PDSS2,DOCK8,SMIM8,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-101:mirSVR_lowEffct hsa-miR-101:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.86E-133 2.72E-129 9.37E-131 8.63E-130 341 1956 "ACADM,ASIC1,NCKAP5,FMNL2,TMEM132B,ADCY6,AXIN2,PWWP2A,PTCHD1,KLHL13,KCTD16,TXNDC16,SPARCL1,ALCAM,AMPH,OGT,EP400,APC,ZFYVE28,ARNTL,ARRB1,NUMB,SLC4A4,EIF4G3,ATP2B2,RIPK1,DOCK11,LINC00847,NRP2,BID,DST,SYNJ1,FUBP1,NAE1,CALB1,KALRN,PTBP2,CAMK2G,VXN,CAST,CH25H,CBR1,USP6,USP2,CD38,DGKI,ARHGEF2,SEPT7,CDH2,CDO1,NOG,SOCS6,PLEKHB1,LHX2,RAB28,FBXO7,QKI,IGLON5,CNN3,AKAP6,LETMD1,COL11A2,SLC4A8,ZNF521,SLC35F1,CPS1,CREM,ENTPD4,RBM39,CRY2,CSF1,FAM169A,APPL1,PUM1,RIMS2,USP6NL,CCDC144A,KIAA0408,GPRASP1,KCTD8,DAPK1,YTHDC1,ZNF804A,ZBTB24,MYEF2,RHOBTB1,SNAP91,SACS,SV2B,SPOCK3,WDR20,DLX1,DMD,CASP8AP2,DPYSL2,PDCD6IP,ECM2,E2F6,AASDH,EBF1,SNX29,EDN1,EDNRB,ANKRD46,FRY,YAF2,KMT5B,EGR3,GOLGA7,EIF4G2,MRNIP,RGS17,ELN,STARD3NL,DCTN4,USPL1,VPS13B,EPB41L2,ENPP6,RABEPK,SRRM1,CDKL3,RRAGB,ADGRV1,FKTN,MED12L,FGFR3,TMEM164,FHL1,POLK,SEC23B,RGPD5,FLT1,ANKFY1,C2orf88,HVCN1,TPK1,ATP6V1H,DOT1L,OGA,ZMAT1,MEGF10,GABRG1,GAD1,MTHFD2,C15orf41,KIAA1841,TUBGCP4,ADAM28,GFRA2,PPARGC1A,TOX3,LOXL3,FERMT2,PRUNE2,GPR37,TMEM121B,GRIA2,RNF165,FAM222A,UBE2QL1,ZHX1,AGBL5,AGFG1,HSF2,CELF5,RBPJ,IL12A,ZNF678,INPP5B,KCNH2,KIF2A,PAXBP1,HECTD2,SMAD1,SMAD9,AQP11,MATN2,SHC3,MEIS1,MEIS2,PPM1L,AFDN,ADAM22,NEXMIF,BEX5,NCAM2,NFE2L2,NNAT,PCBP3,NTRK2,IGSF11,OPA1,CNTN3,PDE4A,PDE4D,PFKFB2,PCDH18,PLXNB1,STRN3,EXOSC10,CCDC144B,LRRN3,PPP2R5E,PKIA,EPDR1,MAPK9,CNNM2,CNTLN,PTCH1,BDNF-AS,PTN,TMEM260,ZIK1,PTPN13,PTPRO,TMEM231,SH3TC2,FAT4,FAM184A,RASGRF2,RBBP6,RET,GTDC1,SLC25A36,RNASEL,RPE,NEK11,SPIN3,ZC3H14,MCMBP,PTGR2,FAM161B,MEG3,ATAT1,CLIP1,ZNF568,TRAPPC13,SALL1,SCP2,SMPD3,FOXRED1,CHD9,FBXO11,FNDC3A,FHOD3,ANKRD6,NUBPL,ABLIM3,EPN2,DHX30,WDR47,ZNF430,SLC6A11,SEPHS1,ARHGEF40,RCOR3,SNCA,SNRPN,TRERF1,SOX3,SOX11,KDM3A,SP4,PEG10,ZC3H13,SPTAN1,RBM26,ZNF621,CLASP2,ITPRID2,SAMSN1,ZC4H2,SS18,NXT2,CEP68,SULF2,KLHL7,SYNE2,ARHGEF9,ADAMTS17,PLCB1,SYPL1,COBL,ANKRD28,C12orf76,TACR1,PJA1,MCF2L,TAF9,PDLIM2,ALG1,TBCEL,TRIM2,RPGRIP1L,USP22,GPRIN3,TEK,FAM200B,PMS2CL,C18orf54,ITGB3BP,AP4E1,GPR161,AKTIP,SYNPO2,METTL3,TRIO,STXBP4,SGK3,TUBB1,UGT8,ZNF709,WIPF1,P2RY12,WRN,CLDND1,RICTOR,GUSBP1,ZNF24,ZNF540,ZNF154,TMEM237,ZNF177,ZFAND5,MEIS3,TMEM178A,HPS4,WNK3,PDSS2,RGS7BP,FAM13C,DOCK8,RTN4,HNRNPA3,TRAM2-AS1,ADAMTS10,FXR1,IFT88,NETO2,JPH3" MicroRNA hsa-miR-1208:mirSVR_lowEffct hsa-miR-1208:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.07E-133 4.51E-129 1.51E-130 1.39E-129 339 1936 "TMEM132B,ADD1,USP31,KIAA1211,DPY19L2P4,HECW2,RTL9,OSBPL8,CC2D2A,TAOK1,AMPD2,C6orf89,MYH7B,PPFIA4,EPB41L5,CDK13,NCOA1,NUMB,ATP1B3,ATP2A2,RIPK1,DOCK11,TTLL9,BACH1,ADGRB3,BID,SYNJ1,WASF1,PTBP2,CAMK2G,SLC25A14,SPAG9,RUNX1T1,PRC1,CBR1,ZNF501,CLDN10,USP2,CBFA2T2,SCARB1,C1orf52,DGKI,DCLK1,CCPG1,CLGN,CACNA2D2,FOXN3,RAB33A,FAM19A5,QKI,FHL5,AKAP7,FAM149A,RCHY1,MYRIP,ZFP28,RBM39,HAPLN1,HINFP,GDA,TRIM69,CS,LRIG1,ARHGEF10,IPCEF1,PDE4DIP,PLXNA4,PLCXD3,RIMS2,KIAA0408,GAPVD1,HDAC4,EARS2,KCTD8,DGKB,TMEM170A,PABPC5,GIT2,ELMSAN1,LYPD1,DDX46,GUCD1,SV2B,CHRDL1,GRIN3A,DMD,DOCK2,DMTF1,ARRDC4,ECM2,DUSP9,ANKRD46,SEMA3D,YAF2,MRO,KMT5B,AASS,EIF5,STX2,SRRM1,IGSF6,VPS26C,ANKMY1,ZNF585B,RPS6KC1,FCGRT,STRADA,SLC9B2,GTF2IRD2,FGF1,MEX3B,PCYOX1,SYNCRIP,RGPD5,SLC37A3,NELFCD,SMC2,UFM1,ATP6V1H,ATP2C1,ZNF605,DOT1L,ZMAT1,MEGF10,GABBR1,IP6K3,MTHFD2,DISC1,INPP5K,CPLX2,KIAA1841,TUBGCP4,TUBA8,MSTN,WASHC2A,NFU1,PCDH17,GGT7,CRCP,RAB30,MSL3,ZNF638,KDM2B,KCNMB4,TDRKH,GRB10,COQ10A,KAT7,PSIP1,FAM107A,RNFT2,MIER3,ELOVL5,AGBL5,C9orf129,DHX35,IRF8,ZNF546,DISP2,ZNF678,INPP1,ITPKB,METTL21A,CREG2,KIF2A,A1BG-AS1,STXBP5,LIMS1,HECTD2,ZNF667-AS1,MAN2A2,MBNL1,EFHB,LRP1B,MEF2C,MEST,KCTD6,PPM1L,AFDN,MMP16,DBNL,MXI1,ZC3H12B,NOVA1,NTRK2,OCRL,OPA1,P2RX7,GLIPR1L2,CNTN3,DPY19L2P2,PCSK5,PDE3A,PDE1B,GPR85,PFKFB2,PFKFB4,NLGN3,TMIE,PIK3R1,SNX10,ANKRD16,TRHDE,POU6F1,LRRN3,PPP2R5E,PPP3CA,PRKACB,MAPK4,GRAMD1C,BCAS3,APTX,DEF8,ANKHD1,MTMR10,SPDL1,PTPRB,PTPRE,PTPRG,PTPRO,PID1,ZNF793,ZCWPW1,OXR1,DPF2,RET,GTDC1,RGS12,SLC25A36,NUDT11,ZFHX4,C12orf49,NEK11,ARMH4,FBXW7,KIAA0895L,LRRK2,SALL1,SARS,PRCD,SCP2,FNIP1,GALNT10,MRAS,SUPT20H,TRA2B,ZFP30,FRMPD1,CHD9,FBXO11,WDR37,FAM81A,PPP4R3A,WDR47,SLC6A8,ZNF430,SEPHS1,SLC11A1,SLC12A2,SMARCA4,IFT122,ANKRD36,KIF13A,LMBRD1,SNRPN,PDZRN3,BDP1,SOX15,ZSWIM8,HECW1,MYCBP2,ZNF423,NFASC,LMO3,ZNF621,POGZ,LARP4,KANK1,SULF2,SEPT3,STXBP1,PRRC2C,ARHGEF9,SYPL1,MTCL1,CAMTA1,EXOC7,FAM208A,TBCEL,KIAA0930,SATB2,TCF12,DOCK9,SLC19A3,TNS2,SIRT1,ITGB3BP,AP4E1,ASXL3,KAT6B,TP53BP2,C9orf85,PPIL6,SSBP2,CLHC1,ZNF610,RPL7L1,PLEKHH2,USP1,VLDLR,RBFOX3,CLIP2,LAT2,CLDND1,RICTOR,XRCC4,ZNF711,ZNF17,MICU3,TRIM9,AGMO,ZNF138,ZNF142,REEP1,TMEM237,AMZ1,SMARCAD1,SLC30A4,PRDM10,HPS4,FIP1L1,HNRNPA3,TMEM63C,CASC15,ACTR3B,ADAMTSL3,NLRP3,NETO1,SOCS4" MicroRNA hsa-miR-342-3p:mirSVR_lowEffct hsa-miR-342-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.86E-133 4.95E-129 1.60E-130 1.47E-129 334 1879 "KCNH8,SYS1,KLHL32,AP2A1,TBC1D14,AK2,SPOP,PCDH10,BBOX1,FAM135A,PITPNM2,AMPD3,ANK2,CCDC146,MAP4K3,SUGT1P4-STRA6LP-CCDC180,UPRT,NT5C3B,TNRC6C,SHROOM2,SEMA4G,MADD,ZSCAN18,NCOA1,STX16,ZNF583,N4BP2L1,ATP6V0A1,TTLL9,ADGRB2,LINC00847,KSR1,BMP7,SYNJ2,AP1M1,WASF1,IL33,CACNA1B,DDR1,CACNB4,CALB1,SPAG9,RUNX1T1,ZNF501,MTMR7,SLC16A4,SCARB1,ENTPD6,CRLF1,CFL2,SRSF11,MS4A7,NRXN3,STOML1,VAX2,C4orf33,QKI,CNR1,AKAP7,LETMD1,MAGED1,COX4I1,TOGARAM2,CDC42BPB,RBM39,SH2B1,CS,SEC24C,OSBPL3,IPCEF1,SIPA1L1,SOCS5,ERC2,PHF14,CTH,PUM1,RIMS2,DOCK4,GAPVD1,TBC1D5,IST1,DGKB,ARMCX4,ZBTB24,ELMO1,KIAA0319,POM121,SNAP91,SV2B,WDR20,RAB39B,DNAH9,MED12,NR1D2,DOCK2,DMTF1,DPH1,DTNA,ECM2,FAM78B,TOM1,DNAJB6,AASDH,EBF1,HEYL,KLHL5,TMTC1,OPTN,APH1A,KMT5B,ASB3,IRAK4,PCOLCE2,COQ7,STX2,SPEG,MRPL10,DNAJC27,ANKMY1,RASL12,ADGRV1,F5,REEP2,ACSL4,TUBB3,CHST15,FGF12,FLNC,TMEM107,PDLIM5,ZNF605,CELF1,CGREF1,DOT1L,ABLIM2,MEGF10,HRASLS5,CHL1,GABRB3,IQGAP2,ZNF559,DISC1,SEPT9,KIAA1841,NEU3,PCDH17,ZNF276,CRCP,RNPS1,DBF4,GLYR1,TNRC6A,ZNF638,ZNF782,PRUNE2,TDRKH,FUT10,CCDC184,GPR37,GRB10,CACFD1,ATE1,PRDM5,RNF165,GSTM5,PSIP1,FAM107A,RNFT2,FAM222A,PADI2,TNFAIP8L3,NEGR1,HSPA1L,MSL1,FAM95B1,INPP5B,KHK,LINC00634,KIT,IPO5,PAXBP1,SYTL4,MAPT,LYPLAL1,MARK3,MBD1,SCAMP5,AFDN,MSI1,MSR1,MT1M,THYN1,MYO5A,MYO7A,NBL1,VWA2,NOVA2,SMIM11A,SETD4,PCSK1,PDE4D,PFKFB2,DUSP26,ZNF655,FAM216A,PCDH18,LRP12,SH3KBP1,PPARA,PPP2R5E,RASGEF1B,PKIA,PRKCB,EPDR1,MASP1,CNNM2,WBP1L,LAMA1,WDR25,CNTLN,PTPRN,TMEM231,SUSD4,ENOX1,RBBP6,RADX,ZDHHC14,FIGN,RGS3,RGS4,RIC8B,NUDT11,RNASEL,GSTCD,PCMTD2,RPE,ZC3H14,LRRK2,ATAT1,RXRA,ZNF331,AP1AR,DGLUCY,FAM102A,FERMT1,KIF16B,HKDC1,FBXO11,NLGN1,DZIP1,EPN2,FAM214B,SLC6A8,ELMO2,BTBD7,SLC22A4,TET1,CPEB4,ZFP1,CDK5RAP2,IFT122,MBD5,CMTR2,SNRPN,TRERF1,NMNAT2,SPP1,ZNF423,SPTAN1,IQSEC2,SPART,NFASC,LMO3,ATP10B,TROVE2,POGZ,ITPRID2,SEPT8,ADHFE1,SEPT3,COBL,ANKRD12,CAMTA1,TAL1,IQCE,DMXL2,KIAA0930,CUX2,SYNE1,PUM2,TNS2,ARHGAP9,ZNF106,BHLHB9,FAM124A,R3HDM1,CSMD1,DOK6,NEIL2,NUTM2A,TSN,SSBP2,RPL7L1,UBTF,PLEKHH2,USP1,CCDC14,TBC1D15,XRCC4,ZFP37,CRB2,LYPD6,ZBTB38,TMEM237,EML6,MEIS3,DHX33,CADM2,NT5M,SLC38A1,RNF103,VPS35L,SEMA3B,PPP1R3F,EPM2A,FZD3,KAT6A,ACTR3B,JMJD1C,NHSL1,NETO2,NETO1,RNF146,JPH3" MicroRNA hsa-miR-181a-2*:mirSVR_lowEffct hsa-miR-181a-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.52E-132 1.41E-128 4.30E-130 3.96E-129 328 1817 "KLHL32,ADCY6,TMCC3,RNF157,ADD1,ADRA1D,ZNF608,MTUS1,HECW2,TBC1D14,KIAA1324,AK2,HFM1,CEP126,ARHGAP20,MARCH4,DOC2A,AMPH,OGT,PHF12,EPB41L5,APOC2,CDK10,SPTBN4,CDK13,NCOA1,TMEM108,EIF4G3,ATP2A2,ZNF583,ATP6V0A1,TTLL9,BACH1,LINC00847,KSR1,BMP7,SYNJ1,C5,RAB29,WASF1,CA8,CA12,CALB2,HAP1,CAMK2A,ISPD,NFS1,CLDN10,USP6,USP2,MTMR7,CD38,LRBA,SEPT7,DCLK1,LRRFIP1,L3MBTL4,DLGAP1,TIGD7,CACNA2D2,ASIC3,NRXN3,CLTC,ABCG2,CNN3,FAM149A,LETMD1,COX4I1,CNRIP1,SEC31B,ENTPD4,RBM39,HINFP,RGS6,DZIP3,KIAA0040,UBXN2A,USP6NL,DOCK4,GAPVD1,TBC1D5,MATR3,KIAA0586,DGKB,DGKG,SCRN1,ELMSAN1,MFAP3L,KLHL3,RHOBTB1,SACS,SPOCK3,CPEB2,ACOT8,TOM1,DNAJB6,E2F5,SNX29,EDN1,CNNM1,RASGRP1,KLHL5,FAM13A,PHF20L1,GOLGA7,TMEM35A,C8orf37,PAN3,EMX2,VPS13B,EPHB1,SRRM1,DENND4A,CEP85L,ETV1,ANKMY1,KATNAL1,ADGRV1,CLVS1,ABCA8,FAM198B,TBC1D16,SCML2,FCGR3A,SLC9B2,BAIAP2,FHL1,MEX3B,PCYOX1,AGAP2,FLNC,PSD2,SLC37A3,C2orf88,POMT1,STAMBP,CAMKK2,ATP6V1H,CGREF1,FYN,SDCBP2,ZNF234,ZNF274,SIGLEC8,IGSF5,ADAM28,GHR,RNPS1,RAB30,KCNMB4,ADGRA3,GRB10,BTN2A1,ZBTB49,SOX21,LINGO1,ADAMTS6,ZHX1,SYNPO,ZNF491,SHISA6,SMAP1,IDH3A,FAM95B1,GAREM2,SCIN,FAM69A,METTL21A,KIT,IPO5,STXBP5,GPR155,MAP6,MAPT,LYPLAL1,MATN2,MEIS1,MEIS2,MEST,PTOV1,HS6ST3,MYO6,RTL5,NCAM2,IDNK,PCBP3,SLC11A2,NTRK2,NTRK3,DPY19L2P2,PCDH8,PCDH9,GPR85,PFKFB2,CCSER2,XRN1,FAM216A,PCDH18,PURG,LRP12,SCHIP1,EPB41L4B,CCDC144B,MAPK10,HYDIN,RELN,CNNM2,WDR25,CNTLN,PTPRB,EML5,PTPRO,RADX,KHDRBS2,ZDHHC14,RDX,REV3L,GTDC1,RGS12,RIC8B,TMLHE,GSTCD,CYB561D1,ROBO1,KIRREL1,YY1AP1,ELP2,MRAP2,SNX22,NEK11,FBXW7,SPIN3,MCMBP,ABCA11P,CLIP1,NCBP3,RMI1,ATXN2,SCP2,FOXRED1,TRA2B,COPZ1,HKDC1,AMBRA1,FNDC3A,SLA,KANSL3,PKNOX2,SLC8A1,SLC12A2,SLC14A1,CPEB4,ZFP1,DMRTC1,MYH15,KIF13A,CMTR2,TMCC1,USP33,ZSWIM8,SP4,HECW1,ZNF423,ZC3H13,TSPYL2,CLASP2,TROVE2,POGZ,SS18,ELOVL4,NEK4,SEPT8,DIP2A,KLHL7,NECAB1,VPS13A,PLCB1,TMEM150C,SYN2,TACC1,MTCL1,PJA1,CAMTA1,TAL1,ADGRL3,SATB2,SZT2,PCDHGA11,FAM189A1,HIF3A,SIK3,RNF216P1,FAM200B,DICER1-AS1,ITGB3BP,SLC44A1,ARL10,MTMR14,ASXL3,TLR4,ERCC6L2,RIMBP2,TPM1,TRIO,TSN,RPL7L1,UGT8,FLRT2,VSNL1,LAT2,LYPD6,ZNF177,ZNF225,STOX2,PRDM10,HPS4,URM1,SLC17A7,PARP11,PDSS2,HRASLS,FZD3,DOCK8,TIGD6,KLHDC1,NETO1,SENP7,JPH3" MicroRNA hsa-miR-107:mirSVR_lowEffct hsa-miR-107:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-132 1.46E-128 4.30E-130 3.96E-129 340 1955 "ABR,SYN3,NDRG3,ADCY6,CCDC85A,ADD1,PLEKHH1,UNC5A,ADRB2,AP2A1,ZNF608,MTUS1,KLHL13,OSBPL1A,OSBPL6,SEMA6A,ALCAM,ARHGAP20,GPRASP2,AMPH,AMT,LCORL,APC,USP37,MADD,IGDCC4,ZFYVE28,CDK13,STK33,PCDHGB4,NUMB,TMEM108,ATP2B2,DOCK11,ADAM15,BACH1,ADGRB3,SEC11C,SYNJ2,FUBP1,SCAPER,MTMR3,C5,MYRF,CACNA1B,CACNB4,SPAG9,KRIT1,USP2,SRSF11,ASIC3,MS4A7,ARHGAP22,RAB33A,DGCR9,FBXO7,CNN3,AKAP6,COL9A1,TBPL1,AKAP12,ANKRD44,CRYM,CSF1,CSNK1G3,IPCEF1,SOCS5,CST3,DZIP3,ERC2,USP6NL,ARHGAP32,KATNAL2,HDAC4,TMEM170A,ARMCX2,ELMO1,TIAM2,SACS,WDR20,DMD,DMPK,USP3,SLC29A4,DYNC1I1,NR1D2,CPEB2,SLC12A6,MAMLD1,DNAJB6,ABCC5,DNM1L,GOLT1B,EDIL3,SEMA3D,EGFR,EIF4G2,COPS4,PAN3,DCTN4,USPL1,RCAN2,LRRC17,GPHN,ERBB4,SPEG,VPS26C,SIRPB1,EZH1,NRN1,TAOK3,STRADA,GORAB,SEC24B,PRKAG2,SCARA3,UBE2E3,HPCAL4,SYNCRIP,FOXO3,SEMA4D,FLT1,PSD2,SMC2,ZNF605,PRELID3A,CELF1,ST6GALNAC3,MEGF11,GAD1,FAM120B,GALC,IP6K3,C15orf41,IGSF5,ALDH1L1,TUBA8,CYP46A1,NFU1,USP19,COPS8,SPIN1,ZNF638,GNG4,GPER1,TMEM121B,STMN2,GRM8,CLASRP,RNF165,COQ10A,FAM107A,ADAMTS6,RASSF8,FRMD3,ZNF491,AGFG1,LRRC75A,SHISA6,ICA1,IRF8,SCIN,ZNF678,KCND2,KCNH2,KCNQ3,IPO5,LMO2,ASPRV1,MAP6,MAT2A,CHIC1,TM6SF1,MEF2C,MEIS2,MITF,MMP16,MN1,MSR1,MT1M,NBL1,NDP,NINJ2,NME4,VWA2,OPA1,ZNF827,PAX6,PCDHGC3,PCDH9,PCSK5,PDE4B,ENPP2,SLC10A4,SEMA5B,PIK3R1,PKD1,PURG,PRIMPOL,MAPKAP1,EXOSC10,ING3,RETREG2,EPB41L4B,MINDY2,PPM1B,PPP2R2B,PRKAB2,PKIA,EPDR1,GRAMD1C,PRPH,MASP1,RELN,CNNM2,SAMD9,WBP1L,DEF8,PIGG,SPDL1,PTN,PTPN13,PTPRB,PTPRE,ACSM5,TTC13,TMEM255A,RAD51D,SH3TC2,NWD1,RASGRF1,RBBP6,KHDRBS2,REV3L,PRRT2,GTDC1,RGS4,ALG9,PNMA8A,ELP2,CCDC102B,ABCA11P,KCNIP3,ZNF568,DGLUCY,SAFB,ATXN2,ATXN7,SCN7A,PRCD,ZFP2,SEC14L1,FOXRED1,TRA2B,SCAF8,SGK1,FRMPD1,ST6GAL1,PREX2,DHX30,KDM4D,CCDC88A,ATF7IP,GKAP1,SMARCC2,MBD5,KIF13A,SNRPN,IZUMO4,PEG10,DBNDD2,NFASC,ATP10B,TROVE2,SSTR1,NEK4,SEPT8,CEP68,PHLDB1,DNAJC9,SYN1,SYN2,SYP,SYPL1,MMS19,MTCL1,CAMTA1,TAF9,TAL1,AGTPBP1,TCF4,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,PMS2CL,TMEM9,TLR4,ERCC6L2,PIK3R5,TPM1,SYNPO2,PPIL6,HIRA,UGT8,WNT7A,XPO1,ZIC1,KCNT2,TRIM9,NDRG4,ZBTB38,REEP1,TMEM237,DPYSL5,EMSY,CADM2,PRDM10,RNF103,CIAPIN1,ITM2C,TRIM16L,RGS7BP,FZD3,DOCK8,NHSL1,FXR1,AP3B2,SOCS4,SPATA13" MicroRNA hsa-miR-103:mirSVR_lowEffct hsa-miR-103:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-132 1.46E-128 4.30E-130 3.96E-129 340 1955 "ABR,SYN3,NDRG3,ADCY6,CCDC85A,ADD1,PLEKHH1,UNC5A,ADRB2,AP2A1,ZNF608,MTUS1,KLHL13,OSBPL1A,OSBPL6,SEMA6A,ALCAM,ARHGAP20,GPRASP2,AMPH,AMT,LCORL,APC,USP37,MADD,IGDCC4,ZFYVE28,CDK13,STK33,PCDHGB4,NUMB,TMEM108,ATP2B2,DOCK11,ADAM15,BACH1,ADGRB3,SEC11C,SYNJ2,FUBP1,SCAPER,MTMR3,C5,MYRF,CACNA1B,CACNB4,SPAG9,KRIT1,USP2,SRSF11,ASIC3,MS4A7,ARHGAP22,RAB33A,DGCR9,FBXO7,CNN3,AKAP6,COL9A1,TBPL1,AKAP12,ANKRD44,CRYM,CSF1,CSNK1G3,IPCEF1,SOCS5,CST3,DZIP3,ERC2,USP6NL,ARHGAP32,KATNAL2,HDAC4,TMEM170A,ARMCX2,ELMO1,TIAM2,SACS,WDR20,DMD,DMPK,USP3,SLC29A4,DYNC1I1,NR1D2,CPEB2,SLC12A6,MAMLD1,DNAJB6,ABCC5,DNM1L,GOLT1B,EDIL3,SEMA3D,EGFR,EIF4G2,COPS4,PAN3,DCTN4,USPL1,RCAN2,LRRC17,GPHN,ERBB4,SPEG,VPS26C,SIRPB1,EZH1,NRN1,TAOK3,STRADA,GORAB,SEC24B,PRKAG2,SCARA3,UBE2E3,HPCAL4,SYNCRIP,FOXO3,SEMA4D,FLT1,PSD2,SMC2,ZNF605,PRELID3A,CELF1,ST6GALNAC3,MEGF11,GAD1,FAM120B,GALC,IP6K3,C15orf41,IGSF5,ALDH1L1,TUBA8,CYP46A1,NFU1,USP19,COPS8,SPIN1,ZNF638,GNG4,GPER1,TMEM121B,STMN2,GRM8,CLASRP,RNF165,COQ10A,FAM107A,ADAMTS6,RASSF8,FRMD3,ZNF491,AGFG1,LRRC75A,SHISA6,ICA1,IRF8,SCIN,ZNF678,KCND2,KCNH2,KCNQ3,IPO5,LMO2,ASPRV1,MAP6,MAT2A,CHIC1,TM6SF1,MEF2C,MEIS2,MITF,MMP16,MN1,MSR1,MT1M,NBL1,NDP,NINJ2,NME4,VWA2,OPA1,ZNF827,PAX6,PCDHGC3,PCDH9,PCSK5,PDE4B,ENPP2,SLC10A4,SEMA5B,PIK3R1,PKD1,PURG,PRIMPOL,MAPKAP1,EXOSC10,ING3,RETREG2,EPB41L4B,MINDY2,PPM1B,PPP2R2B,PRKAB2,PKIA,EPDR1,GRAMD1C,PRPH,MASP1,RELN,CNNM2,SAMD9,WBP1L,DEF8,PIGG,SPDL1,PTN,PTPN13,PTPRB,PTPRE,ACSM5,TTC13,TMEM255A,RAD51D,SH3TC2,NWD1,RASGRF1,RBBP6,KHDRBS2,REV3L,PRRT2,GTDC1,RGS4,ALG9,PNMA8A,ELP2,CCDC102B,ABCA11P,KCNIP3,ZNF568,DGLUCY,SAFB,ATXN2,ATXN7,SCN7A,PRCD,ZFP2,SEC14L1,FOXRED1,TRA2B,SCAF8,SGK1,FRMPD1,ST6GAL1,PREX2,DHX30,KDM4D,CCDC88A,ATF7IP,GKAP1,SMARCC2,MBD5,KIF13A,SNRPN,IZUMO4,PEG10,DBNDD2,NFASC,ATP10B,TROVE2,SSTR1,NEK4,SEPT8,CEP68,PHLDB1,DNAJC9,SYN1,SYN2,SYP,SYPL1,MMS19,MTCL1,CAMTA1,TAF9,TAL1,AGTPBP1,TCF4,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,PMS2CL,TMEM9,TLR4,ERCC6L2,PIK3R5,TPM1,SYNPO2,PPIL6,HIRA,UGT8,WNT7A,XPO1,ZIC1,KCNT2,TRIM9,NDRG4,ZBTB38,REEP1,TMEM237,DPYSL5,EMSY,CADM2,PRDM10,RNF103,CIAPIN1,ITM2C,TRIM16L,RGS7BP,FZD3,DOCK8,NHSL1,FXR1,AP3B2,SOCS4,SPATA13" MicroRNA hsa-miR-519c-3p:mirSVR_highEffct hsa-miR-519c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.88E-132 2.17E-128 6.06E-130 5.58E-129 304 1555 "KCNH8,NCKAP5,ADCY6,GALNT13,SLC24A4,ZNF608,HFM1,SPARCL1,SRPX,ABCD2,ARHGAP20,OGT,LRCH2,SEMA7A,EP400,LINC00173,STK33,ZBTB10,RASL11B,SLC4A4,ATP2A2,ZNF583,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,IL33,HIP1R,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,IGLON5,SLC4A8,RCHY1,AHCTF1,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,PITPNM3,UBXN2A,PHF14,PPP6R2,RUBCN,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,MYEF2,FBXL5,PLPPR4,SACS,WDR20,DMD,USP3,CPEB2,DMTF1,DPYSL2,DNAJB6,DNM1L,EBF1,ANKRD46,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,CALCRL,CEP85L,RASL12,EZH1,ACSL4,TAOK3,CEP78,SLC9B2,FGF13,FGF14,PRKAG2,MEX3B,FOXF2,RGPD5,JKAMP,NBEA,UFM1,TPK1,ATP2C1,NSG1,GABBR1,B4GALNT1,ERAP1,DISC1,SULT1C4,ZNF276,COPS8,GLYR1,TOX3,ZNF638,LUZP2,GNAL,GRB10,PRDM5,CIT,RNF165,RABL2A,PSIP1,ADAMTS6,GUCY1B1,HAS2,FRMD3,MIER3,HNMT,IRF8,LRRCC1,ZNF678,FAM69A,KCND2,KCNN2,CREG2,KIF5A,LIG4,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,LRP1B,MID1,MITF,XRRA1,MSR1,LAYN,MYT1,NACA,NELL2,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,NTRK2,OCRL,P2RY1,GPR137C,CNTN3,ENPP2,GNG2,CCSER2,TMEM38A,JAKMIP1,SCHIP1,EPB41L4B,SH3KBP1,PPM1B,PPP2R5E,PPP3CA,PKIA,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTPRB,ACSM5,ZSCAN2,QDPR,PID1,CEP97,SLC25A48,USP47,RAD17,RBBP6,ZDHHC14,RET,RFX3,SLC25A36,ZFHX4,CCDC82,SETD5,PNMA8A,ROBO1,RORB,ZNF671,LRRK2,RTN1,RYR3,SALL1,CSRNP3,PRCD,SCP2,HSPA4L,ARX,KIF16B,CPEB3,SHC4,CHD9,SYBU,SLA,FAM81A,KANSL3,CCDC88A,BTBD7,RCOR3,ANKRD36,KIF13A,SNRPN,TMCC1,KDM4B,TRERF1,DOK5,HECW1,TEX2,IQSEC2,SPART,PBLD,CLASP2,TROVE2,POGZ,LARP4,ERBIN,ADHFE1,NECAB1,PLCB1,SYT1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,AKTIP,SLC44A1,THRA,TLR4,R3HDM1,KAT6B,STXBP4,TSC1,UBC,FAM155A,UBE3A,FLRT2,VLDLR,TBC1D15,LAT2,XPO1,PCDH20,ZBTB14,ZNF711,MICU3,ZNF74,MKRN3,TCEAL7,CELF4,REEP1,FSTL5,ANKS1B,MAP3K12,MFF,FAM47E,WNK3,PLSCR4,RGS7BP,SMIM8,HNRNPA3,PHTF2,CASC15,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-425:mirSVR_lowEffct hsa-miR-425:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-132 2.18E-128 6.06E-130 5.58E-129 329 1831 "ACADM,CLK4,KDM5D,PSMG3-AS1,AXIN2,PWWP2A,KIAA1211,ADRA1D,MTUS1,KCTD16,HACE1,TXNDC16,AK2,ZNF578,C1QTNF3,ALCAM,ARHGAP20,FAM135A,GPRASP2,SYT13,ZFAT,SUGT1P4-STRA6LP-CCDC180,PKP4,KCNAB2,MAGEE2,SHROOM2,ZFYVE28,ARNTL,CADPS,MARK4,NUMB,ATP2A2,DPY19L3,ATP6V0A1,BACH1,BCL7A,NRP2,KSR1,DST,SYNJ2,CA8,CACNA1B,CACNB4,CALB1,THSD7A,MTMR7,SYNGR3,CDC25B,TIGD7,CCPG1,CLGN,FOXN3,NDST3,RAB28,TPP1,C4orf33,LETMD1,AKAP5,ABI3BP,RCHY1,SMARCAL1,HAPLN1,RNF14,ANKRD44,GDA,TRIM69,SNCAIP,SEC24C,CSNK1G3,PDE4DIP,PLXNA4,FAM169A,CTH,PUM1,HDAC9,ZFYVE16,CENPL,MATR3,MAML1,PABPC5,BRINP1,DNAL1,DBN1,ARMCX4,ELMSAN1,TIAM2,FBXL5,DDX46,ALKBH8,WDR20,ZNF582-AS1,DMD,NR1D2,DPP6,DPYSL2,RCAN1,ARRDC4,DTNA,DNAJB6,E2F6,EDN1,ANKRD46,FRY,PHF20L1,EGR3,DCTN4,USPL1,VPS13B,RABEPK,MRVI1,ABCA8,RPS6KC1,KAT8,SEC24B,PRKAG2,UBE2E3,IP6K2,FLT1,POMT1,PDLIM5,ZNF605,ST6GALNAC3,STAU2,AP4B1,GABRG2,ZNF274,ERAP1,SYT17,DISC1,CPLX2,NEU3,ALDH1L1,ARFIP1,TOX3,TNRC6A,HTATSF1,LUZP2,DCLK2,ADGRA3,GPD2,FUT10,LPAR4,GPR34,DIDO1,GRM8,BVES,SOX21,HLF,SYNPO,TCEAL6,DHX35,IRF8,FAM95B1,SOWAHA,RBPJ,KIAA1755,IL12A,LRRTM1,ITGAM,JAK2,KCNB1,KCND1,IPO5,LAMP2,LIMS1,PAXBP1,NCOA7,SMAD1,SMAD9,MAN2A2,MBNL1,MEIS2,POC1B,AFF1,AFDN,XRRA1,MMP16,MN1,ADAM22,PTOV1,LAYN,MYO5A,MYO9A,NFE2L2,NPY,DNHD1,CHAMP1,P2RX7,TREM2,GLIPR1L2,PAX6,PCDH8,PCDH9,PDE3A,PDE4D,PDE1B,PDPK1,GNG2,PFKFB2,NALCN,SNX10,RETREG1,LRP12,PPARA,PPP2R5E,PRKACB,ANKHD1,MTMR10,PTPRG,RAD17,FAM66C,FAT4,ZDHHC14,FIGN,RFX3,ZNF532,TMLHE,C12orf49,PNMA8A,ROBO1,CCDC25,CCDC102B,ATP8B4,PTGR2,ZNF568,AP1AR,RMI1,ATXN2,SCN8A,ZFP2,SUPT20H,COPZ1,HSPA4L,SCAF8,FERMT1,CPEB3,MYO18A,FNDC3A,FHOD3,PEX26,EPN2,WDR47,FAM214B,SLC6A8,SLC9A5,SLC12A4,ELMO2,ATF7IP,LGI3,ZKSCAN3,SMARCD3,SNCA,KIF13A,LMBRD1,DOP1A,NMNAT2,KDM4C,TEX2,PEG10,ZBTB43,RBM26,SPART,ATP10B,CAMTA2,ZC4H2,ST5,STAU1,ZSCAN29,TTBK2,ADHFE1,KANK1,SULF2,SEPT3,NECAB1,PRRC2C,NUDT10,SYPL1,TAF9,FAM208A,AGTPBP1,TBCEL,DMXL2,TPCN2,TCF12,TEK,PMS2CL,SIRT1,AP4E1,TIAM1,HEY1,ACTR6,TLR4,ERCC6L2,LRRC8A,RASD2,TPM1,NPL,RGMB,ZNF346,PDSS1,RUNDC3B,TTC3,SGK3,RPL7L1,GORASP1,UGT8,PLEKHH2,VSNL1,RBFOX3,RICTOR,ZNF24,TRIM9,ZNF45,AGMO,ZNF70,TCEAL7,SPIRE1,DHX33,EMSY,PRDM10,TMEM178A,PLSCR4,SMIM8,JMJD1C,NHSL1,ZDHHC20,NETO2,NETO1,ZNF30" MicroRNA hsa-miR-301a:mirSVR_highEffct hsa-miR-301a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.99E-132 3.91E-128 1.06E-129 9.73E-129 310 1623 "RALGAPA1,CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,BEND6,HECW2,KLHL13,OSBPL1A,WDR35,HFM1,ADGRF5,SPARCL1,ALCAM,SRPX,ABCD2,FAM135A,LRCH2,LCORL,PHF12,APAF1,APC,LINC00173,STK33,NCOA1,TMEM108,STX16,ZNF582,ZNF583,N4BP2L1,DPY19L3,ADAM23,TTLL9,ADGRB3,NRP2,DST,C5,CALB1,CABP7,THSD7A,KALRN,CAMK2A,CAST,RUNX1T1,CERS5,USP6,SEPT7,TIGD7,CCPG1,CFL2,PLAA,TPP1,CLTC,SRP14-AS1,AKAP7,ARMC8,FAM149A,RCHY1,CLOCK,CREM,GDA,CSF1,LRIG1,SIPA1L1,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,HDAC9,DCAF8,ZFYVE16,LONRF1,MATR3,DAPK1,SPATA2,YTHDC1,FBXL5,DDX46,RHOBTB1,SPOCK3,WDR20,RAB39B,DPYSL2,DNAJB6,ABCC5,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,KMT5B,EGR3,ASB3,CERCAM,PAN3,DCTN4,ENPP6,RABEPK,TLR7,RASL12,ABCA8,ACSL4,GORAB,MED12L,FGF14,SEC23B,FOXF2,SYNCRIP,COQ5,JKAMP,NBEA,MEGF10,B4GALNT1,ERAP1,TMEM8B,ARFIP1,ADAM28,DBF4,RAB30,TNRC6A,ZNF638,KDM2B,MAP7D2,LUZP2,RAB40B,ZNF782,FERMT2,GPD2,PRUNE2,GRB10,GRIA2,SERP2,ZNF496,CIT,RNF165,FAM222A,BACH2,HNF4G,HNMT,IRF8,MSL1,ZIC5,LRRCC1,ZNF678,CDH20,KCNN3,CREG2,TTYH2,LIG4,LIMS1,MAP4,MATN3,MBNL1,MEIS2,LYRM9,ZNF862,MYT1,NELL2,CNOT4,OCRL,OPA1,GPR137C,PCDH9,PCSK5,PDE1C,PFKFB2,DUSP26,SERPINI1,CCSER2,JAKMIP1,PURG,LRP12,PPP2R5E,PPP3CA,PSD,MTMR10,STK32A,EML5,PTPRG,ZSCAN2,PID1,CEP97,RAD17,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,RFX3,UBR7,SLC25A36,C12orf49,KLHDC8A,CARF,ROBO2,EPHA10,BAALC,LRRK2,CLIP1,RTN1,ZNF354C,CCDC112,DGLUCY,TNFRSF19,PEAR1,KIF21A,ARX,KIF16B,CHD9,SYBU,SEC31A,BTBD3,WDR47,KANSL3,SLC8A1,CCDC88A,SLC14A1,BTBD7,ZNF667,SNAP25,KIF13A,USP33,TRERF1,DOK5,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,FBXW11,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,SLC44A1,BHLHB9,ERCC6L2,R3HDM1,CSMD1,TNS1,STXBP4,TSC1,TUBB1,UBC,FAM155A,BCL2L13,CCDC136,CCDC14,WRN,ZNF711,MICU3,TRIM9,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,SMARCAD1,UPF3A,MAP3K12,MFF,STOX2,KCNAB1,WNK3,PLSCR4,RGS7BP,DNAH10,UBE3B,CASC15,NHSL1,FXR1,FRMD6" MicroRNA hsa-miR-301a:mirSVR_lowEffct hsa-miR-301a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.02E-132 4.49E-128 1.18E-129 1.09E-128 328 1824 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,PWWP2A,PTCHD1,PCDH19,KCTD16,CC2D2A,AK2,PCDH10,PITPNM2,AMPD3,SEMA7A,CCDC146,MAP4K3,MYH7B,EPB41L5,TNRC6C,PPFIA3,IGDCC4,DOCK11,KSR1,BMPR1B,FUBP1,SGCE,LDLRAD4,CAMK2G,USP2,DCLK1,LRRFIP1,MAGI1,NOG,SRSF11,MS4A7,EPS15L1,NRXN3,FBXO7,C4orf33,QKI,HECTD1,FHL5,CNN3,CNR1,IQCK,SLC4A8,TBPL1,BAG4,ZNF521,HAPLN1,SUSD5,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,LIN54,MAML1,DGKB,DGKG,TMEM170A,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KIAA0319,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,USP3,DNAH9,MED12,NR1D2,CPEB2,SLC25A18,DRP2,DTNA,ECM2,DNM1L,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPB41,GPHN,CEP85L,EXTL2,KATNAL1,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FDFT1,FECH,OLFM1,TMEM164,PRKAG2,MEX3B,PCYOX1,RGPD5,FLT1,ANKFY1,STAU2,GABBR1,GABRA3,ZNF44,FAM120B,GALC,RAPGEF6,ZNF274,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,TOX3,CBX1,GPT2,ADGRA3,FUT10,MCHR1,GPER1,PCLO,GRM2,LINC01089,KAT7,SOX21,ADAMTS6,GUCY1A1,MAP4K5,ATOH8,RASSF8,HAS2,FRMD3,MIER3,HLF,IGF1,NIM1K,NME9,SLC35G1,KCNN2,KIT,IPO5,MAP2,MARK3,ADAM11,CHIC1,LRP1B,MEIS1,AFF1,AFDN,ZNF680,ADAM22,MYO9A,NEXMIF,IDNK,NOVA1,NPTX1,NPTX2,TBC1D25,GLIPR1L2,DPY19L2P2,PDE4B,PDE4D,GNG2,CYTL1,PFKFB3,NLGN3,PIK3C2A,PIK3R1,FAM216A,PDZRN4,STRN3,SCHIP1,ING3,POU6F1,PPM1B,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,SNRK,ELOVL2,ZIK1,PTPRD,PTPRE,PPP2R3C,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,FIGN,RIC8B,RNASEL,CCDC82,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,RYR3,ZNF331,FAM192A,SATB1,SCN8A,GALNT10,FOXRED1,SUPT20H,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,FAM81A,CDK5RAP3,SLC12A2,CPEB4,GKAP1,MAST1,SMARCD3,RCOR3,CABCOCO1,SNRPN,FNBP1,KDM3A,KDM4C,TSPYL2,RBM26,LARP4,STAU1,SEPT8,DIP2A,ADHFE1,STXBP1,SYT1,SLC37A2,TACC1,TACR1,EXOC7,PDLIM2,AGTPBP1,TBCEL,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,SYNE1,PCDHB7,USP32P1,FRYL,GALNT17,RIMBP2,PARD3,NPL,DOK6,NR2C2,SMUG1,TRPS1,HIRA,RPL7L1,EIF4ENIF1,UBE3A,LINC00689,TOM1L2,VLDLR,P2RY12,CLDND1,GUSBP1,XRCC4,PCDH20,ZNF24,CELF4,SPIRE1,EMSY,SLC38A1,EVI5,LINC02210,PRDM10,NAV3,FIP1L1,FAM47E,PDSS2,FAM13C,AMN1,DOCK8,RTN4,PHTF2,FBXO36,GJC2,FAM219B,JMJD1C,RNF170,NETO2,NETO1,SOCS4,JPH3" MicroRNA hsa-let-7f-2*:mirSVR_highEffct hsa-let-7f-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-131 7.54E-128 1.93E-129 1.78E-128 320 1737 "RALGAPA1,ASIC1,ACHE,CLK4,NDRG3,CCDC85A,AXIN2,PLEKHH1,PWWP2A,PTCHD1,ADRB2,ZNF608,MTUS1,KLHL13,KIAA1324,CC2D2A,SPARCL1,ALCAM,ZFAT,DPP10,PHF12,APBA2,UPRT,LGR5,RGS20,RASL11B,ATP1B3,RNF182,ALDH7A1,DOCK11,BACH1,SEC11C,BMP7,DST,NAE1,MTMR2,C5,IL33,CA8,KALRN,PTBP2,CH25H,PRC1,KRIT1,USP6,CBFA2T2,C1orf52,DGKI,LRRFIP1,CFL2,SRSF11,SOCS6,NDST3,LHX2,RAB33A,C4orf33,QKI,HECTD1,CNR1,ARMC8,AKAP6,RTTN,SLC35F1,ENTPD4,RBM39,CS,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,SUSD5,VCAN,PDE4DIP,PHACTR3,PPP1R16B,USP6NL,GPRASP1,RIPOR2,MAML1,DGKB,DAPK1,BRINP1,ZNF804A,TIAM2,KIAA0319,DDX46,SNAP91,WDR20,GRIN3A,RAB39B,NR1D2,CDON,CPEB2,CASP8AP2,PDCD6IP,DTNA,ABCC5,E2F5,E2F6,AASDH,EDN3,EDNRA,ANKRD46,SEMA3D,OPTN,PHF20L1,MBNL2,GOLGA7,TENM1,PLEKHA1,CALCRL,LRRC17,GPHN,MRPL37,CDKL3,ETV1,EYA1,F8,ABCA8,FAM198B,RPS6KC1,ST3GAL6,FGF13,FGFR3,PRKAG2,SUCO,UBE2E3,SYNCRIP,RGPD5,PSD2,SLC37A3,HVCN1,STAMBP,TPK1,CAMKK2,ATP6V1H,ATP2C1,KHDRBS3,ZNF44,FAM120B,ZNF234,IQGAP2,ERAP1,C15orf41,GCNT2,MSTN,ARFIP1,PCDH17,PPARGC1A,ZNF638,MAP7D2,LUZP2,GNAO1,FERMT2,GPT2,ADGRA3,PRUNE2,AP4S1,RASSF8,HAS2,ZHX1,MIER3,HMGCR,ZDHHC15,TCEAL6,MSL1,ZIC5,RBPJ,INPP1,INPP5B,INSM1,KIF5A,KIT,STXBP5,STMN1,PAXBP1,HECTD2,PIK3AP1,MAP2,MARK1,MAT2A,MBNL1,LRP1B,SRSF12,MITF,MN1,ZNF680,MYCN,MYO9A,ALDH1L2,CNOT4,NOVA2,NPTX1,NRCAM,CHAMP1,LOC100128398,TREM2,CNTN3,PCDH8,PDE3A,NLGN3,FAM218A,CCSER2,STRN3,PSAT1,SCHIP1,ING3,IRX1,PPM1B,PPP2R2B,PPP2R5E,PPP3CA,PRKACB,CEP41,MAPK10,GRAMD1C,MASP1,CNTLN,ANKHD1,BDNF-AS,TMEM260,TMEM255A,ZNF493,OXR1,RBBP6,KHDRBS2,MSANTD2,RET,MORC4,PBRM1,ZFHX4,DCUN1D2,CARF,GSTCD,ROBO1,ROBO2,ELP2,PTGR2,ABCA11P,KCNIP3,ZNF568,SALL1,SATB1,ATXN2,FNIP1,SUPT20H,SH3GL3,SHC4,CNKSR2,WDR37,FAM81A,EPN2,SLC8A1,SLC14A1,SMARCA4,SNCA,MBD5,KIF13A,TMCC1,MYO16,FAM219A,TRERF1,MYCBP2,RBM26,LMO3,PBLD,ITPRID2,NKAIN2,ERBIN,NXT2,STAU1,RGL1,DIP2A,STXBP1,NECAB1,RHBDL3,VPS13A,SYN2,COBL,ANKRD28,ANKRD12,CAMTA1,FAM208A,MGRN1,CUX2,PCDHB9,USP32P1,FRYL,SIK3,TEK,ZFPM2,ITGB3BP,SLC44A1,TIAM1,TLR4,BEX4,NPL,STXBP4,ANKRD20A2,SSBP2,USP1,TBC1D15,WIPF1,ZNF781,KLC2,GUSBP1,XRCC4,PCDH20,ZFP37,ZNF138,ZBTB38,FSTL5,CADM2,NAV3,RGS7BP,FAM13C,DOCK8,RTN4,SMIM8,FXR1" MicroRNA hsa-miR-194:mirSVR_lowEffct hsa-miR-194:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.16E-131 2.33E-127 5.82E-129 5.36E-128 336 1926 "ACADM,CLK4,RNF157,PLEKHH1,PWWP2A,BEND6,RTL9,OSBPL1A,TBC1D14,OSBPL6,WDR35,CC2D2A,ARHGAP20,ZFAT,USP37,AQP6,CDC14B,CASK,CCAR2,SLC4A4,ADAM23,BACH1,LINC00847,BBS2,MPDZ,SEC11C,CFLAR,BMP7,WASF1,CACNA1B,LURAP1,CALM1,PTBP2,CAMK2G,CAST,HIP1R,CERS5,CDH2,CCPG1,CHN2,NDST3,LHX2,PLAA,ABCG2,CNGA3,CNR1,COL4A5,COL11A2,RTTN,MYRIP,ZNF521,FAM171B,CLOCK,CRHBP,ANKRD44,OSBPL3,CSNK1G3,SOCS5,PHACTR3,CNTNAP2,FAM169A,DZIP3,APPL1,CTH,RUBCN,DOCK4,HDAC9,ARHGAP24,ZNF337,KCTD8,SCRN1,SPOCK2,DBI,GIT2,PITPNC1,MYEF2,LYPD1,GSDME,POM121,SACS,SPOCK3,SEC16A,RAB39B,DMD,HS3ST2,SLC29A4,NR1D2,DPYSL2,ARRDC4,ECM2,DUSP9,MAMLD1,RASGRP1,KLHL5,FAM13A,PHF20L1,SUGP2,MRO,GOLGA7,ASB3,EIF4G2,TMEM35A,PAN3,VPS13B,EPB41L2,LRRC17,GPHN,DENND4A,NCALD,RRAGB,EYA1,ABCA8,SCML2,SEC24B,SLC9B2,FGFR1,FGFR3,TMEM164,MEX3B,SYNCRIP,C2orf88,UFM1,PDLIM5,ST6GALNAC3,SARAF,MEGF11,GALNT15,GABRG1,DISC1,CPLX2,PPARGC1A,ZNF638,KIAA1958,KDM2B,HTATSF1,GNAL,FERMT2,ADGRA3,GPD1,GPD2,STON1,PCLO,GRB10,KAT7,ZBTB45,FAM107A,MAP4K5,UBE2QL1,FRMD3,HLF,AGBL5,NEGR1,CELF5,SMAP1,IRF8,IGF1,LRRCC1,IL6R,FAM69A,ITPKB,KPNA5,STXBP5,CYP27C1,LIFR,SYTL4,SMAD1,PIK3AP1,MAP2,MBNL1,MBP,MEIS1,KITLG,MYCN,MYO7A,NCAM2,ZC3H12B,NCF2,NELL2,NF1,NFE2L2,NOVA1,NRCAM,NTRK2,NUCB2,CHAMP1,OPRL1,CDK18,ENPP2,PIK3R1,ZNF655,RETREG1,XRN1,JAKMIP1,SMIM7,PURG,LRP12,PSAT1,EPB41L4B,PPP2R5E,RASGEF1B,MAPK4,EPDR1,HYDIN,DIRAS2,WBP1L,PIGG,PTCH1,MTMR10,PTK2,STK32A,ZIK1,PTPRO,C1orf109,TUG1,PPP2R3C,CEP97,ZNF793,SH3TC2,FAT4,ZCWPW1,OXR1,RBBP6,REV3L,FIGN,UBR7,KCTD17,KLHL11,ZNF532,ALG9,RORB,ELP2,CCDC102B,NEK11,ZC3H14,RXRA,NCBP3,ZNF331,SEMA6D,SATB1,SMPD3,SUPT20H,KIF27,TRA2B,SGK1,KIF21A,SH3GL3,ARX,KIF16B,CHD9,FNDC3A,CNKSR2,SYBU,DZIP1,ANKRD6,FAM81A,PEX26,PPP4R3A,BTBD3,EPN2,SLC8A1,ARHGEF40,SLC14A1,SMARCA4,ANKRD36,KIF13A,LMBRD1,TMCC1,TRERF1,KDM3A,MYCBP2,CDK19,ATP10B,PBLD,LARP4,SSPO,ELOVL4,SEPT8,STXBP1,NECAB1,SYNE2,COBL,ANKRD28,C12orf76,TACC1,FBXW11,ATMIN,SATB2,ZFP90,ZEB1,PHF24,NSD1,USP32P1,CRTC1,FRYL,PMS2CL,ZFPM2,ZMAT3,ZNF106,AKTIP,TIMP4,R3HDM1,RGMB,SYNPO2,PDSS1,RUNDC3B,NEIL2,TRO,TTC3,CLHC1,FAM155A,UBE3A,UGT8,PLEKHH2,XPO1,SLC47A2,ZNF711,KCNT2,ATP6V0E2,ZNF70,ZNF138,TMEM237,ZNF195,FTSJ1,ZFAND5,UPF3A,DHX33,PRDM10,ADAMTS9,HPS4,KCNAB1,FAM47E,PHTF2,JMJD1C,FXR1,FRMD6,NETO1" MicroRNA hsa-miR-519b-3p:mirSVR_highEffct hsa-miR-519b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.49E-131 2.51E-127 6.13E-129 5.64E-128 289 1410 "KCNH8,NCKAP5,ADCY6,GALNT13,SLC24A4,ZNF608,HFM1,SPARCL1,SRPX,ABCD2,ARHGAP20,OGT,LRCH2,SEMA7A,EP400,LINC00173,STK33,RASL11B,SLC4A4,ZNF583,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,IL33,HIP1R,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,IGLON5,SLC4A8,RCHY1,AHCTF1,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,PITPNM3,UBXN2A,PHF14,PPP6R2,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,MYEF2,FBXL5,PLPPR4,SACS,WDR20,DMD,USP3,DPYSL2,DNAJB6,DNM1L,EBF1,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,CALCRL,CEP85L,RASL12,EZH1,ACSL4,TAOK3,CEP78,SLC9B2,FGF13,FGF14,PRKAG2,MEX3B,FOXF2,RGPD5,JKAMP,NBEA,UFM1,ATP2C1,NSG1,GABBR1,B4GALNT1,ERAP1,DISC1,SULT1C4,ZNF276,TOX3,ZNF638,LUZP2,GNAL,GRB10,PRDM5,CIT,RNF165,RABL2A,PSIP1,GUCY1B1,HAS2,FRMD3,MIER3,IRF8,LRRCC1,ZNF678,KCND2,KCNN2,CREG2,KIF5A,LIG4,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,LRP1B,MID1,MITF,XRRA1,MSR1,MXI1,LAYN,MYT1,NACA,NELL2,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,NTRK2,OCRL,P2RY1,GPR137C,CNTN3,GNG2,CCSER2,TMEM38A,JAKMIP1,SCHIP1,EPB41L4B,PPM1B,PPP2R5E,PPP3CA,PKIA,MASP1,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTPRB,ACSM5,ZSCAN2,QDPR,PID1,CEP97,SLC25A48,USP47,RAD17,OXR1,RBBP6,ZDHHC14,TRIM68,RET,RFX3,SLC25A36,ZFHX4,CCDC82,SETD5,PNMA8A,ROBO1,RORB,ZNF671,LRRK2,RTN1,RYR3,SALL1,CSRNP3,PRCD,SCP2,HSPA4L,ARX,KIF16B,CPEB3,SHC4,CHD9,SYBU,FAM81A,KANSL3,CCDC88A,BTBD7,RCOR3,ANKRD36,KIF13A,SNRPN,TMCC1,KDM4B,USP33,TRERF1,DOK5,TEX2,IQSEC2,SPART,CLASP2,TROVE2,POGZ,LARP4,ERBIN,ADHFE1,NECAB1,PLCB1,SYT1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,AKTIP,SLC44A1,THRA,TLR4,R3HDM1,STXBP4,TSC1,UBC,FAM155A,UBE3A,FLRT2,VLDLR,TBC1D15,XPO1,PCDH20,ZBTB14,ZNF711,ZNF45,ZNF74,MKRN3,TCEAL7,CELF4,REEP1,FSTL5,ANKS1B,MAP3K12,MFF,FAM47E,WNK3,PLSCR4,RGS7BP,SMIM8,PHTF2,CASC15,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-448:mirSVR_highEffct hsa-miR-448:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.83E-131 3.26E-127 7.76E-129 7.15E-128 309 1624 "RALGAPA1,AS3MT,FMNL2,KLHL32,ADD1,PWWP2A,DPY19L2P4,HECW2,CC2D2A,AK2,C1QTNF3,SPARCL1,ABCD2,DOC2A,OGT,SUGT1P4-STRA6LP-CCDC180,PARG,UPRT,SFMBT2,ZFYVE28,ARNTL,CDK13,NCOA1,NUMB,ATP2B2,ZNF582,DPY19L3,MPDZ,DST,SYNJ1,SCAPER,CALB1,ZNF555,KALRN,PTBP2,CAST,CLDN10,SCARB1,SEPT7,CFL2,SRSF11,NDST3,SULT4A1,IGLON5,CNR1,ARMC8,COL4A5,MYRIP,ZNF521,ZFP28,CREM,RBM39,RNF14,CLIP3,OSBPL3,SOCS5,SLITRK5,DZIP3,APPL1,PHF14,USP6NL,CCDC144A,BOC,DOCK4,TCAF1,ARHGAP24,ZFYVE16,EARS2,LIN54,DAPK1,BRINP1,GIT2,ZNF804A,MYEF2,KIAA0319,GSDME,SPOCK3,DYNC1I1,NR1D2,CPEB2,CASP8AP2,DPYSL2,DTNA,MAMLD1,GOLT1B,EBF1,ANKRD46,RASGRP1,KLHL5,TMTC1,MBNL2,EGR3,AASS,PLEKHA1,CALCRL,PAN3,LRRC17,EPHB1,GPHN,SRRM1,DENND4A,ETV1,F8,ARMCX1,CLVS1,SH3YL1,ACSL4,CHST15,FER,SUCO,MEX3B,SEC23B,ATP13A4,FLT1,SLC37A3,NBEA,SMC2,HVCN1,PDLIM5,CELF1,FYB1,ZNF44,GABRB3,RAPGEF6,IP6K3,C15orf41,DISC1,GATM,SULT1C4,MSTN,MSL3,KDM2B,HTATSF1,RAB40B,FERMT2,PCLO,PRDM5,FAM19A2,ZBTB49,GUCY1A1,ZHX1,HNF4G,ZDHHC15,CELF5,SMAP1,EID2B,ZNF181,ZNF546,SCIN,INPP5B,ITPKB,KCNB1,KCND2,KCNK3,STXBP5,PAXBP1,HECTD2,PACRG,PIK3AP1,MARK1,MAT2A,MATN3,MBD1,MBNL1,SHC3,MEF2C,MEIS1,MITF,ADAM22,MXI1,MYH3,NEK1,CNOT4,NOVA1,NOVA2,NPR2,NRCAM,SMIM11A,NUCB2,SETD4,GLIPR1L2,CNTN3,PAX6,PCDH8,PCDH9,PRTG,PDE4D,GPR85,PIK3C2A,FAM216A,SMIM7,MTRF1L,SCHIP1,ING3,SH3KBP1,MINDY2,PPP2R5E,PRKAB2,PRKCB,GDPD1,DCHS2,SAMD9,DEF8,SNRK,BDNF-AS,PTPRD,EML5,PTPRE,PTPRH,QDPR,CEP97,USP47,RAD51D,ZNF793,OXR1,REV3L,ERI2,KIF7,ZFHX4,ROBO2,RORB,ARMH4,SPIN3,ABCA11P,ZNF568,SATB1,ATXN2,HSPA4L,SCAF8,CHD9,FNDC3A,NLGN1,ANKRD6,ABLIM3,SLA,WDR47,KDM4D,SLC12A2,CPEB4,ZFP1,ANKRD36,LIMCH1,TMCC1,DBNDD2,CDK19,RBM26,LMO3,ZNF302,SAMSN1,SS18,NXT2,RGL1,PLCB1,SYN1,TMEM150C,SYN2,COBL,ANKRD28,TACC1,PJA1,TBCEL,RPGRIP1L,DOCK9,PUM2,USP32P1,FRYL,TEK,SIRT1,ZFPM2,TLR4,ERCC6L2,R3HDM1,PARD3,NPL,RGMB,SYNPO2,CLHC1,PLEKHH2,VLDLR,TBC1D15,WIPF1,RICTOR,ZNF711,MICU3,AGMO,ZNF74,TCEAL7,CELF4,SPIRE1,UPF3A,CADM2,SLC38A1,RNF103,HPS4,PPP1R3F,KCNAB1,FAM47E,PDSS2,FAM13C,FZD3,FBXO36,JMJD1C,FXR1,FRMD6,IFT88,NETO1,GAN,ZNF30,JPH3" MicroRNA hsa-miR-199a-5p:mirSVR_lowEffct hsa-miR-199a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-130 1.28E-126 2.98E-128 2.74E-127 327 1833 "DGCR6,ABR,ACHE,KDM5D,TMEM132B,PLEKHH1,USP31,BEND6,SLC24A4,AP2A2,KCTD16,HACE1,TBC1D14,OSBPL8,CC2D2A,TAOK1,SEMA6A,ALCAM,ABCD2,ARHGAP20,SYT13,AMPD2,AMPD3,ANK2,SUGT1P4-STRA6LP-CCDC180,UPRT,CDK10,TMEFF1,ARRB2,CADPS,MARK4,ATP1B3,ZNF582,DPY19L3,ATP6V0A1,ADAM23,TTLL9,ADAM15,ADGRB2,BCHE,BID,PROM1,KSR1,SYNJ1,ARHGEF7,MTMR2,WASF1,MYRF,CA4,CA8,CACNB4,CALB1,KALRN,PTBP2,CH25H,PRC1,CBLN1,CBR1,ZNF501,METTL6,LRBA,CDH2,LOC730101,DLGAP1,CLGN,CBARP,RAB33A,ABCG2,SULT4A1,SRP14-AS1,HECTD1,AKAP7,AKAP6,SLC4A8,SMARCAL1,MYRIP,ZNF385A,SLC35F1,CREM,SEC24C,ARHGEF10,PDE4DIP,RASGEF1C,KIAA0040,GREB1,PUM1,DCAF4,BOC,DCAF8,INTS1,DGKG,DAPK1,IP6K1,BRINP1,ARMCX4,HEPH,DDX46,PLPPR4,SNAP91,TMCC2,EXOG,DMD,DNM1,DNAH9,NR1D2,DPH1,DPP6,DPYSL2,DRP2,ABCC5,E2F5,EDIL3,EDNRA,EDNRB,HEYL,FRY,YAF2,SUGP2,KMT5B,IRAK4,EIF1,LRRC17,CDKL3,DNAJC27,CLVS1,FCGR1A,FCGRT,KAT8,ZNF589,FGF11,PRKAG2,SUCO,MEX3B,PCYOX1,SYNCRIP,ANKFY1,AKAP3,JKAMP,POMT1,CINP,ERGIC3,AP4B1,OGA,MEGF10,ZNF274,IP6K3,DISC1,SRRM4,GATM,ALDH1L1,WASHC2A,SESN1,MMADHC,USP19,GGT7,MALT1,TCERG1,COPS8,GLI2,MAP7D2,GRB10,AP4S1,ADAMTS6,NCKAP1L,MIER3,HLF,VSIG4,ELOVL5,HNMT,NEGR1,ICA1,ZNF546,GAREM2,SCIN,KTN1,STMN1,HECTD2,MAP2,MAP4,MATN2,MBP,ADAM11,PPM1L,POC1B,MITF,MN1,MPP2,MYCN,MYO9A,RTL5,NEFM,NEK1,NOVA1,SLC11A2,NTRK3,IGSF11,OCRL,GLIPR1L2,PDE3A,PDE4D,ENPP2,PFKFB2,PFKFB4,PIK3R1,FAM218A,GPSM2,SLC25A23,PLXNB1,PURG,PMP22,ING3,SH3KBP1,FSD1,POU6F1,PPM1B,RASGEF1B,EPDR1,MAPK7,MAPK9,GRAMD1C,WDR25,CNTLN,BDNF-AS,PTK2,STK32A,PTPRB,PTPRD,PTPRE,PTPRG,PTX3,ZNF615,TMEM255A,FAM66C,FAM184A,ROGDI,RASGRF1,MORC4,GTDC1,RFX3,SLC25A36,PBRM1,SUGCT,CARF,CCDC25,EPHA10,RPL15,MAP6D1,RPS20,TRAPPC13,DGLUCY,ATXN7,TNFRSF19,R3HDM2,CNKSR2,BTBD3,ZNF430,SLC12A2,NAPB,SLC22A4,SNRPN,FAM126B,MYO16,PDZD2,SP4,MYCBP2,KDM4C,SPTB,ATP10B,CEP68,VPS13A,TMEM150C,ARC,SYN2,SYPL1,TACC1,TAL1,FAM208A,FBXW11,KLHL4,ZFP90,TPCN2,TRIM2,DOCK9,FAM189A1,SLC19A3,HIF3A,TEK,AP4E1,GPR161,SLC44A1,MTMR14,TMEM9,BEX4,RIMBP2,TPM1,RGMB,PDSS1,STXBP4,TRPS1,TTC3,SGK3,FAM155A,ZNF709,LAT2,ZNF781,GUSBP1,ZNF28,ZNF70,NDRG4,MKRN3,CELF4,SMARCAD1,UPF3A,SLC30A4,MAP3K12,SLC38A1,GDPD5,LINC02210,PRDM10,RNF103,RGS7BP,FZD3,ADAMTSL3,JMJD1C,FXR1,NETO2,JPH3" MicroRNA hsa-miR-383:mirSVR_lowEffct hsa-miR-383:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.72E-130 1.52E-126 3.46E-128 3.19E-127 321 1766 "RALGAPA1,ACADM,NDRG3,ADD1,USP31,ADORA2A,RNF150,BEND6,MTA3,AP2A2,OSBPL1A,OSBPL6,SPOP,ALCAM,ARHGAP20,PCDH10,UNC79,DPP10,LRCH2,MYH7B,PKP4,BCAS1,TNRC6C,CDC14B,CDK13,NCOA1,TMEM108,SLC4A4,ATP1B3,ATP6V1G2,LINC00847,BBS2,ZNF599,BMP7,ARHGEF7,C5,RAB29,WASF1,IL33,CFAP410,CALB1,CAPN3,CH25H,HIP1R,C1orf52,DCLK1,LRRFIP1,MAGI1,CRLF1,NUMBL,CFL2,FOXN3,CHRNA4,RAB28,NRXN3,DGCR9,SRP14-AS1,FHL5,ARMC8,COL11A2,ZFP28,CNRIP1,GDA,ABCG1,LRRC3B,OSBPL3,CST3,CTH,PUM1,ZSCAN23,CCDC144A,KIAA0408,ARHGAP24,KCTD8,IP6K1,DNAL1,ARMCX4,YTHDC1,ZNF804A,ELMO1,MFAP3L,RHOBTB1,PLPPR4,SACS,WDR20,EXOG,GRIN3A,ACOT8,PDCD6IP,ABCC5,E2F5,EDIL3,SNX29,CNNM1,RASGRP1,OPTN,EIF4G2,PLEKHA1,C8orf37,DCTN4,EPB41,RCAN2,LRRC17,RABEPK,SRRM1,NCALD,RRAGB,FAM198B,TMEM132C,SUCO,FOXO3,ANKFY1,SLC37A3,DCTN2,COQ5,EFCAB2,NBEA,SMC2,PDLIM5,CAMKK2,ZNF605,KHDRBS3,ST6GALNAC3,MEGF10,GABRB3,B4GALNT1,ZNF274,IQGAP2,MTHFD2,GATM,TUBGCP4,GPR162,GGT5,HPGDS,ZNF638,LUZP2,DCLK2,GP1BB,PCLO,STMN2,DIDO1,SPACA9,PRDM5,GRM8,CIT,ADAMTS6,GUCY1B1,MAP4K5,ZHX1,NEGR1,FAM95B1,C2orf72,RBPJ,IL6ST,KCND1,KCNF1,LAMP2,STMN1,LIFR,LIG4,PAXBP1,PIK3AP1,GPR155,MAPT,MBD1,MBNL1,MBP,CHIC1,MEF2C,KCTD6,MID1,AFF1,MSR1,HS6ST3,LYRM9,MYO6,ZNF862,BEX5,ZC3H12B,NF1,NFE2L2,VWA2,NPR2,SLC11A2,NRCAM,TBC1D25,CHAMP1,PAX6,DPY19L2P2,PDE4B,PDE4D,ENPP2,PIK3R1,CCSER2,SLC25A23,PURG,PMP22,LRP12,EXOSC10,PPP2R2B,PPP2R5E,PPP3CC,KANSL1,PRKACB,PKIA,RELN,VPS13C,CNTLN,ZSCAN32,PTPRB,PTPRE,PEX2,TTC13,CEP97,SLC25A48,ZNF793,NWD1,ROGDI,OXR1,RBBP6,ZMAT4,TRIM68,GTDC1,RGS12,PRIMA1,RIC8B,LGI2,CCDC82,ALG9,GSTCD,CYB561D1,KIRREL1,CCDC25,FBXW7,GLDN,ATAT1,KCNIP3,SEMA6D,SEC14L1,CASC3,SCAF8,PPM1E,FERMT1,ST6GAL1,CCDC92,SEC31A,SLC2A5,PPP4R3A,KANSL3,SEPHS1,CCDC88A,KBTBD4,SLC12A2,ELMO2,GKAP1,MYH15,ANKRD36,SNRPN,FNBP1,ZSWIM8,ZC3H13,CDK19,TSPYL2,ATP10B,SST,SSTR1,ZSCAN29,DIP2A,ADHFE1,KANK1,SLC37A2,PJA1,TBCEL,MGRN1,TCF4,SATB2,TCF12,PCDHB7,USP32P1,ARHGAP9,HIF3A,DICER1,ZFPM2,AP4E1,SLC44A1,TMEM9,ACTR6,FAM124A,CSMD1,PIK3R5,SYNPO2,ELP5,TRIO,TUBB1,VLDLR,WIPF1,GUSBP1,MICU3,ZNF28,ZNF45,POLR3H,SMARCAD1,DHX33,EVI5,GDPD5,LINC02210,STOX2,NAV3,FIP1L1,ITM2C,PLSCR4,FAM13C,AMN1,DOCK8,CASC15,FAM219B,TRAM2-AS1,TTC7A,IFT88,NETO1,LAS1L" MicroRNA hsa-miR-216b:mirSVR_lowEffct hsa-miR-216b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-130 1.61E-126 3.58E-128 3.30E-127 326 1823 "RALGAPA1,KCNH8,METAP1D,XKR4,ADD1,AXIN2,ADRB2,DPY19L2P4,SLC24A4,AP2A2,INTS2,MTUS1,WDR35,OSBPL8,ALCAM,UNC79,PDZD4,AMPH,CDC42BPA,LCORL,KCNAB2,UPRT,PPFIA3,USP37,CASK,TMEFF1,RGS20,STK33,ZSCAN18,NCOA1,ATP1B3,STX16,ATP2A2,ATP6V0A1,RIPK1,BACH1,ADGRB3,BID,CFLAR,PROM1,BMPR1B,RAB29,IL33,PTBP2,HIP1R,KRIT1,METTL6,SYNGR3,SEPT7,ZBED1,MAGI1,SOCS6,CHN2,RAB33A,NRXN3,FBXO7,FAM19A5,MAP4K4,CNGA3,FHL5,CNR1,PCYT1B,ARMC8,COL9A1,AKAP5,ABI3BP,MYRIP,ZNF521,SLC35F1,CLOCK,C2CD2,HAPLN1,ANKRD44,GDA,TRIM69,CS,APPL1,CTH,USP6NL,HDAC9,GPRASP1,ARHGAP32,KATNAL2,GAPVD1,TCAF1,DCAF8,ZFYVE16,EARS2,ZNF337,TM9SF4,KIAA0586,KCTD8,DGKB,SPOCK2,BRINP1,SPATA2,YTHDC1,ZBTB24,ELMO1,ZC3H11A,GUCD1,DLX1,GRIN3A,NR1D2,SLC12A6,DTNA,ABCC5,GOLT1B,AASDH,EDN1,FSD1L,FAM13A,MRO,KMT5B,EGR3,EIF4G2,COPS4,TENM1,C8orf37,PAN3,EIF1,EMX2,EPB41,LRRC17,RABEPK,SRRM1,SPEG,MRPL10,KATNAL1,NRN1,ARMCX1,FCGRT,FGF1,FGFR1,MEX3B,SYNCRIP,SEMA4D,FLT1,ANKFY1,EFCAB2,TRMO,ZNF605,ERGIC3,STAU2,MEGF11,MEGF10,GABRB3,DENND2A,ZNF234,ZNF274,C15orf41,DISC1,NFU1,GHR,COPS8,GLYR1,MSL3,KDM2B,GPR12,ATP2B1-AS1,GRIA2,BTN2A1,RNFT2,SYNPO,HNF4G,ZDHHC15,DHX35,CELF5,SMAP1,SCIN,IBA57,ITPKB,KCNJ16,KCNN2,KIT,HECTD2,MAP2,MAP6,MEIS1,SRSF12,MID1,POC1B,AFF1,ZNF680,NRBP2,MXI1,LYRM9,MYO9A,NEXMIF,BEX5,HNRNPM,P2RY13,NFE2L2,ALDH1L2,NFYA,NPTX2,NTRK2,LOC100128398,ZNF713,P2RX7,GPR137C,PCDH9,PDE4B,PDE1B,PFKFB3,OLA1,TMIE,CCSER2,XRN1,KCTD15,PLIN1,MTRF1L,PURG,LRP12,ING3,RETREG2,SH3KBP1,FSD1,DRAM2,TATDN3,PPP2R2B,PPP2R5E,PRKAB2,RASGEF1B,MAPK4,PRPSAP2,CNNM2,TMEM260,PTX3,TUG1,ZNF493,KHDRBS2,RET,ERI2,FIGN,RGS12,GSTCD,RORB,ELP2,EPHA10,FBXW7,ATP8B4,SGSM1,ABCA11P,ST6GALNAC6,SALL1,SCN7A,SCN8A,PRCD,SCP2,MRAS,FAM102A,SH3GL3,ABLIM3,PREX2,SLC12A2,NAPB,LGI3,CPEB4,DOP1A,TRERF1,BDP1,SOX11,KDM3A,SP4,PEG10,IQSEC2,RBM26,ZNF621,ITPRID2,ZC4H2,NKAIN2,ERBIN,CEP68,RGL1,KANK1,SULF2,COBL,TACR1,ANKRD12,CAMTA1,FAM208A,ADGRL3,AGTPBP1,TBCEL,KLHL4,TCF4,DMXL2,CUX2,TRIM2,GPRIN3,RNF175,AP4E1,ZMAT3,SLC44A1,TIAM1,SYNPO2,PDSS1,RUNDC3B,DCBLD1,UBE3A,BCL2L13,LAT2,XRCC4,ZNF24,ZNF70,CRB2,ZBTB38,DPYSL5,ANKS1B,SPIRE1,MEIS3,CIAPIN1,SLC17A7,KCNAB1,HRASLS,FZD3,DOCK8,ST7,MARCH8,RTN4,UBE3B,SMIM8,TTC7A,NETO1,LAS1L" MicroRNA hsa-miR-550:mirSVR_lowEffct hsa-miR-550:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.53E-130 2.53E-126 5.51E-128 5.07E-127 324 1803 "AS3MT,SYS1,NDRG3,FMNL2,UNC5A,PWWP2A,RNF150,ESYT2,PTCHD1,AP2A2,ZNF608,KIAA1324,WDR35,CC2D2A,CEP126,ARHGAP20,DPP10,CCDC146,PPFIA4,APBA2,PPFIA3,SFMBT2,LINC00173,STK33,MARK4,STX16,ATP2A2,N4BP2L1,KIF1A,TTLL9,ADAM15,ADGRB1,LINC00847,DST,SYNJ2,CA8,THSD7A,CAPN3,SLC16A4,CBFA2T2,SCARB1,SYNGR3,CD38,ENTPD6,CDC25B,LARGE1,MAGI1,CRLF1,CHN2,MS4A7,TPP1,MAP4K4,ARHGEF6,COL4A5,ABI3BP,COX4I1,ZNF521,AKAP12,CRYBB1,ANKRD44,GDA,CLIP3,CS,CSF2RA,ARHGEF10,SIPA1L1,VAC14-AS1,KIAA0040,CTH,PPP6R2,BOC,KATNAL2,HDAC4,ZFYVE16,EARS2,ZNF337,LIN54,TMEM170A,PITPNC1,SPATA2,YTHDC1,MYEF2,ELMO1,GUCD1,SV2B,KIF19,EXOG,RAB39B,DMD,DNM1,DMPK,USP3,SLC29A4,DMTF1,DPH1,RCAN1,DTNB,ECM2,MAMLD1,DNAJB6,DNM1L,EBF1,SNX29,EDNRA,ANKRD46,CNNM1,SUGP2,EPB41L2,CEP85L,ZNF549,SPEG,VPS26C,RASL12,SIRPB1,EYA1,GMPR2,MRVI1,HSPA12B,PTK2B,RACK1,FCGRT,ZNF589,FER,POLR1B,FGF13,POLK,SUCO,IP6K2,EVL,FLYWCH1,EFCAB2,APOPT1,ZNF605,CELF1,CGREF1,MEGF10,GABRB3,ZNF274,TMEM8B,C15orf41,DISC1,GATM,SULT1C4,MSTN,CYP46A1,GGT7,GHR,CRCP,COPS8,GLI2,TOX3,ZNF638,STON1,GRB10,GRIN2C,ZNF496,RNFT2,MAN1B1,VSIG4,HMGCL,AGBL5,CPT1C,DHX35,ZNF546,LRRC25,DISP2,SCIN,INPP5B,NME9,A1BG-AS1,L1CAM,LIMS1,MAN2A2,ZFYVE27,MAPT,MBD1,ADAM11,MEIS1,AFDN,XRRA1,SAMD5,N6AMT1,MYT1,SFR1,CCDC13,NELL2,NNAT,DNHD1,SLC11A2,NTRK3,OGG1,P2RY1,PDE4A,PDE1B,PFKFB4,FAM218A,XRN1,GPSM2,NLE1,PLIN1,PURG,STRN3,PILRA,POU6F1,PPM1B,TATDN3,RASGEF1B,BCAS3,WBP1L,BDNF-AS,PTPRE,PTPRG,RIPOR1,ZSCAN2,TMEM255A,NWD1,TRIM68,UBR7,RGS4,RGS12,ADAL,STK32B,ABCA11P,HUNK,KCNIP3,SBF1,CSRNP3,ATXN7,SMPD3,PEAR1,CASC3,GALNT10,KIF27,FERMT1,SHMT2,HKDC1,AMBRA1,SEC31A,DZIP1,PREX2,PEX26,DHX30,ARHGEF40,SLC9A5,SLC11A1,ELMO2,SMARCD3,KIF13A,CMTR2,PDZRN3,KDM4B,USP33,SOX11,ZSWIM8,NMNAT2,GLT8D1,KDM4C,UNC5B,SPTAN1,NFASC,LHPP,ATP10B,CLASP2,CLSTN2,NKAIN2,ZSCAN29,TTBK2,DIP2A,NUDT10,SYN2,SYT1,TACR1,CAMTA1,EXOC7,PDLIM2,ATMIN,TCEA1,SIN3B,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,RNF216P1,ZFPM2,ITGB3BP,CDH22,GALNT17,LRRC8A,RIMBP2,C9orf85,RGMB,NEIL2,STXBP4,TTTY15,HIRA,UBTF,UCHL1,CCDC14,LMF1,CLIP2,RICTOR,GUSBP1,ZNF24,ZNF74,LYPD6,ZNF189,DPYSL5,PRDM10,CIAPIN1,FAM47E,PDSS2,HNRNPA3,CASC15,IFT88,DPF3,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-4295:mirSVR_lowEffct hsa-miR-4295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.77E-130 2.67E-126 5.67E-128 5.22E-127 307 1614 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,USP31,PWWP2A,PTCHD1,KCTD16,AK2,ADGRF5,SPARCL1,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,PHF12,EPB41L5,TNRC6C,ATP2A2,ZNF582,N4BP2L1,DOCK11,KSR1,BMPR1B,SGCE,LDLRAD4,CALB1,USP2,SEPT7,MAGI1,NOG,SRSF11,MS4A7,EPS15L1,FBXO7,C4orf33,QKI,HECTD1,MAP4K4,RAB26,FHL5,CNR1,IQCK,AKAP5,SLC4A8,TBPL1,AHCTF1,ZNF521,HAPLN1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,MAML1,DGKG,TMEM170A,DAPK1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,RAB39B,NYAP1,USP3,DNAH9,MED12,CPEB2,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,HEYL,TMTC1,FRY,EIF4G2,TENM1,C3orf18,EMX2,RABEPK,SLC43A2,NCALD,CEP85L,TLR7,EXTL2,KATNAL1,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,SCARA3,MEX3B,PCYOX1,ANKFY1,PSD2,JKAMP,STAU2,MSANTD4,GABRA3,ZNF44,GALC,ZNF274,IQGAP2,TUBGCP4,PPARGC1A,DBF4,TOX3,FERMT2,GPT2,ADGRA3,GPR12,MCHR1,GPER1,PCLO,GRIA2,GRM2,LINC01089,KAT7,SOX21,GUCY1A1,MAP4K5,FAM222A,HAS2,FRMD3,MIER3,HLF,AGFG1,IGF1,NIM1K,NME9,SLC35G1,KCNJ16,KCNN2,KIT,IPO5,MAP2,MARK3,ADAM11,CHIC1,MEIS1,AFF1,ZNF680,ADAM22,MYO9A,IDNK,NOVA1,NPTX1,NPTX2,TBC1D25,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,FAM216A,PDZRN4,STRN3,ING3,POU6F1,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,ZIK1,PTPRD,PTPRE,PTPRO,TMEM231,PPP2R3C,QDPR,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,RFX3,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,GLDN,RYR3,ZNF331,SATB1,SCN8A,FNIP1,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,SLC12A2,CPEB4,MAST1,RCOR3,CABCOCO1,SNRPN,FNBP1,KDM3A,TSPYL2,RBM26,LARP4,SEPT8,RGL1,DIP2A,STXBP1,SYT1,ANKRD28,TACC1,TACR1,EXOC7,FAM208A,PDLIM2,AGTPBP1,TBCEL,ATMIN,TCEA1,TCF4,SIN3B,SATB2,TRIM2,RPGRIP1L,SYNE1,DOCK9,PCDHB7,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,RIMBP2,PARD3,NPL,NR2C2,SMUG1,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,LINC00689,TOM1L2,VLDLR,P2RY12,CLDND1,XRCC4,PCDH20,LYPD6,TCEAL7,SPIRE1,SMARCAD1,EVI5,LINC02210,PRDM10,NAV3,KCNAB1,FIP1L1,FAM47E,PDSS2,FAM13C,DOCK8,RTN4,PHTF2,FBXO36,CASC15,FAM219B,RNF170,NETO2,SOCS4,JPH3" MicroRNA hsa-miR-147:mirSVR_lowEffct hsa-miR-147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-130 2.84E-126 5.92E-128 5.45E-127 318 1736 "ACHE,SYS1,ACTN1,FMNL2,GALNT16,GALNT13,UNC5A,PTCHD1,KIAA1324,OSBPL6,AK2,TAOK1,C1QTNF1,SPOP,ALCAM,CARNS1,PCDH10,FAM135A,SYT13,AMPD3,LRFN1,LGR5,MADD,CADPS,MARCH3,PCDHGB4,DYNLL1,ATP2B2,ZNF583,BCS1L,CACNA1A,CACNA1B,CABP7,CALM1,PRC1,CBS,USP6,CD38,L3MBTL4,MAGI1,CCPG1,RAB33A,NRXN3,ABCG2,C4orf33,QKI,IGLON5,FHL5,CNN3,ARHGEF6,CNTN1,IQCK,PCYT1B,CABP1,RTTN,TOGARAM2,ZFP28,CLOCK,RBM39,CLIP3,ABCG1,OSBPL3,FAM169A,UBXN2A,PLCXD3,DCAF4,RUBCN,USP6NL,FAM131B,BOC,HDAC9,EARS2,DGKG,SCRN1,PABPC5,YTHDC1,DGCR5,RUSC2,TMEM130,SPOCK3,DMD,USP3,CD99L2,CPEB2,CASP8AP2,DPP6,DTNA,ECM2,TOM1,DUSP9,DNAJB6,FCF1,CNNM1,YAF2,SUGP2,MBNL2,TNK2,ELN,EPB41,EPB41L2,TLR7,RRAGB,EYA1,ZNF461,FER,FGF1,FGF11,FGF14,HPCAL4,FOXF2,SYNCRIP,EVL,SEMA4D,FLNC,FLYWCH1,NELFCD,CAMKK2,ZNF234,NEU3,ARFIP1,CYP46A1,ADAM28,MMADHC,PCDH17,MALT1,RUNDC3A,ZNF276,SPIN1,GLUL,CBX1,KDM2B,GNAO1,ZNF782,GPD1,STON1,DIDO1,GRIK4,ADAMTS13,BTN2A1,RNFT2,ADAMTS6,IRAK3,UBE2QL1,HMGCL,HNMT,CFAP126,CELF5,C2orf72,ZIC5,INSM1,C2CD4C,SLC35G1,METTL21A,KCND2,KCNN2,IPO5,STXBP5,LAMP2,ZFYVE27,MAP2,MAP6,AQP11,MBNL1,CHIC1,LRP1B,MEIS1,MEIS2,XRRA1,MOV10,DBNL,NRBP2,N6AMT1,MYO7A,RTL5,P2RY13,NFE2L2,ALDH1L2,DNHD1,NRCAM,NTRK2,OGG1,PCDHGC3,PCDH9,CDK18,PDCD2,PDE4D,PDPK1,PFKFB4,SLC25A23,MAPKAP1,POU6F1,MINDY2,PPP3CA,PRKAB2,TMEM260,PTPRO,NKAIN1,CCDC40,RASGRF1,KHDRBS2,CCDC82,SETD5,EXD2,CARF,GSTCD,KIRREL1,PCMTD2,SNX22,RPL15,SPIN3,KIAA0895L,GLDN,LRRK2,ABCA11P,ZNF331,DGLUCY,SEMA6D,SATB1,ATXN7,MRAS,SGK1,MYO18A,CCDC92,NUBPL,DHX30,ARHGEF40,CCDC88A,SLC12A4,BTBD7,SMARCC2,SNAP25,MBD5,SNRPN,DOP1A,PDZD2,ZSWIM8,IQSEC2,CDK19,NFASC,ATP10B,PBLD,TROVE2,CLSTN2,ITPRID2,SSTR2,LARP4,SS18,SSPO,ZSCAN29,SEPT8,DIP2A,ADHFE1,SEPT3,ARHGEF9,SYP,SYPL1,MTCL1,TAF6,ALG1,SMG6,TCF4,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZNF34,THRA,TIAM1,ERCC6L2,PRRT1,PIK3R5,STXBP4,TRPS1,TSC1,FLRT2,CCDC14,LMF1,VSNL1,NPDC1,XRCC4,LGI4,ZNF19,ZNF24,ELFN1,ZNF45,ATP6V0E2,ZNF70,MKRN3,ZNF154,ZNF213,MFF,ADAMTS9,HPS4,VPS35L,SEMA3B,NAV3,RGS7BP,ADAMTSL3,TIGD6,SPATA13" MicroRNA hsa-miR-590-3p:PITA hsa-miR-590-3p:PITA_TOP PITA 7.63E-130 4.27E-126 8.71E-128 8.02E-127 294 1477 "CLK4,FMNL2,KLHL32,CCDC85A,GALNT13,ADD1,AXIN2,USP31,ADRB2,ZNF608,INTS2,PCDH19,HACE1,TBC1D14,OSBPL8,ALCAM,LTBP4,FAM135A,OGT,EP400,MAP4K3,APAF1,APC,GAS7,USP37,TMEFF1,ZBTB10,NCOA1,SLC4A4,DOCK11,NAE1,BTK,JAZF1,CALB1,CALM1,PTBP2,SPAG9,C1orf52,MAGI1,CLGN,CFL2,SOCS6,RAB33A,PLAA,QKI,CNR1,AKAP6,AKAP5,RCHY1,AHCTF1,CLOCK,RBM39,OSBPL3,CNTNAP2,SLITRK5,PPP1R16B,UBXN2A,PHF14,RIMS2,RUBCN,KIAA0408,DOCK4,DCAF8,LONRF1,DGKB,PABPC5,DBT,PITPNC1,MYEF2,TIAM2,KLHL3,DDX46,RHOBTB1,WDR20,DLX1,RAB39B,NR1D2,CPEB2,ARRDC4,DNAJB6,ABCC5,E2F5,SNX29,EDN1,HIPK3,RASGRP1,FSD1L,OPTN,YAF2,MBNL2,KMT5B,GOLGA7,KCTD3,EIF5,PLEKHA1,GPHN,ETV1,EYA1,ACSL4,PTK2B,FKTN,SEC24B,FOXF2,SYNCRIP,ZMYND15,FOXO3,ANKFY1,AFF2,AKAP3,UFM1,KHDRBS3,FYN,GABRG2,RAPGEF6,IP6K3,MSTN,ARFIP1,PCDH17,PPARGC1A,TCERG1,RNPS1,SPIN1,KDM2B,FERMT2,GRIA2,FAM19A2,COQ10A,KAT7,SOX21,GUCY1A1,FAM222A,HAS2,ATXN2L,MIER3,HLF,ELOVL5,GABARAPL2,AGBL5,AGFG1,SMAP1,ITPKB,JAK2,SLC35G1,KCND2,STXBP5,KTN1,SMAD1,MAP2,MARK1,MBD1,MBNL1,CHIC1,LRP1B,MEST,KITLG,AFF1,HS6ST3,MYCN,MYO6,NEXMIF,NCAM2,ZC3H12B,NF1,NME4,IGSF11,CHAMP1,CNTN3,PCDH9,PDE4D,GNG2,PFKFB2,OLA1,XRN1,PURG,TRHDE,STRN3,LRP12,EPB41L4B,PPARA,PPP2R5E,CEP41,CNTLN,MTMR10,PTPRB,TMEM255A,USP47,RDX,RET,REV3L,UBR7,SETD5,C12orf49,CARF,RPL15,LRRK2,CLIP1,SALL1,SEMA6D,SATB1,LRFN5,TNFRSF19,CASC3,TRA2B,SGK1,ZFP30,PPM1E,SHC4,CHD9,FBXO11,FNDC3A,R3HDM2,NLGN1,PPP4R3A,BTBD3,SLC8A1,CCDC88A,SLC12A2,ATF7IP,TET1,CPEB4,GKAP1,RCOR3,SNAP25,SOX11,KDM4C,ZC3H13,CDK19,TSPYL2,SPART,ATP10B,POGZ,SST,LARP4,ERBIN,NXT2,STAU1,ELOVL4,SEPT8,KANK1,ARHGEF9,PLCB1,SYN2,SYPL1,ANKRD28,CAMTA1,ADGRL3,AGTPBP1,TCEA1,WSCD1,TCF4,SATB2,CUX2,PCDHB4,CRTC1,DICER1,SIRT1,ZFPM2,ITGB3BP,AP4E1,AKTIP,SLC44A1,THRA,NACC2,RIMBP2,CSMD1,KAT6B,PDSS1,TRPS1,SGK3,FAM155A,EIF4ENIF1,FLRT2,USP1,TBC1D15,WIPF1,CLDND1,XRCC4,ZNF28,KCNT2,REEP1,TMEM237,EMSY,CADM2,RNF103,WNK3,RGS7BP,KAT6A,HNRNPA3,PHTF2,JMJD1C,MSRB3,RNF146,SOCS4,SENP7" MicroRNA hsa-miR-130b:mirSVR_lowEffct hsa-miR-130b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-129 7.51E-126 1.50E-127 1.38E-126 319 1753 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,PWWP2A,AK2,ADGRF5,PCDH10,PITPNM2,AMPD3,ZFAT,OGT,SEMA7A,CCDC146,MAP4K3,APBB2,APC,EPB41L5,TNRC6C,SLC4A4,ZNF582,DOCK11,KSR1,BMPR1B,SGCE,LDLRAD4,CALB1,CAMK2G,SPAG9,RUNX1T1,USP2,CBFA2T2,CDH2,DCLK1,MAGI1,NOG,CACNA2D2,SRSF11,FOXN3,MS4A7,FBXO7,C4orf33,QKI,HECTD1,IQCK,SLC4A8,BAG4,ZNF521,HAPLN1,CRY2,SIPA1L1,FAM169A,DZIP3,KIAA0040,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,ELMO1,MFAP3L,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,NYAP1,USP3,DNAH9,MED12,SLC12A6,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,HIPK3,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,SLC43A2,TLR7,KATNAL1,REEP2,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,AMOTL2,SCARA3,MEX3B,PCYOX1,ANKFY1,JKAMP,STAU2,GABRA3,ZNF44,GABRG1,GALC,IQGAP2,C15orf41,SEPT9,ALDH1L1,TUBGCP4,AHDC1,PPARGC1A,TOX3,GPT2,ADGRA3,MCHR1,GPER1,PCLO,GRM2,LINC01089,KAT7,SOX21,GUCY1A1,MAP4K5,FAM222A,RASSF8,HAS2,FRMD3,MIER3,HLF,SYNPO,AGBL5,AGFG1,SHISA6,IGF1,NIM1K,SLC35G1,KCNN2,KIT,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LRP1B,MEIS1,AFF1,ZNF680,MXI1,MYCN,IDNK,NELL2,NFYA,NOVA1,NPTX1,NPTX2,TBC1D25,PDE4B,PDE4D,CYTL1,PFKFB3,SEMA5B,PIK3C2A,ZFYVE21,FAM216A,PDZRN4,STRN3,SCHIP1,ING3,SH3KBP1,POU6F1,PKIA,HYDIN,RELN,VPS13C,DEF8,ZIK1,PTPRD,TMEM231,PPP2R3C,QDPR,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,FIGN,RFX3,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,GLDN,RYR3,ZNF331,SALL1,SATB1,SCN8A,SCP2,GALNT10,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,SLC12A2,CPEB4,MAST1,RCOR3,CABCOCO1,SNRPN,KDM4B,PDZD2,FNBP1,KDM3A,KDM4C,PEG10,ZBTB43,TSPYL2,RBM26,LMO3,LARP4,SEPT8,DIP2A,STXBP1,SYT1,TACC1,TACR1,EXOC7,PDLIM2,AGTPBP1,TBCEL,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,SYNE1,DOCK9,PCDHB7,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TLR4,RIMBP2,PARD3,RASD2,RGMB,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,BCL2L13,TOM1L2,VLDLR,P2RY12,CLDND1,RICTOR,XRCC4,PCDH20,ZNF24,SPIRE1,ZNF213,SMARCAD1,EMSY,EVI5,GDPD5,LINC02210,NAV3,FAM47E,WNK3,PDSS2,FAM13C,FZD3,DOCK8,FBXO36,CASC15,FAM219B,RNF170,NETO2,SOCS4,CPNE4,JPH3" MicroRNA hsa-miR-30a:mirSVR_highEffct hsa-miR-30a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.75E-129 9.81E-126 1.92E-127 1.77E-126 328 1857 "RALGAPA1,CLK4,ABHD6,GALNT16,GALNT13,RNF157,ADD1,BRAP,KIAA1211,LRFN2,ADRB2,AP2A1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,VAT1L,USP37,PPP4R4,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B2,DPY19L3,ADGRB3,SEC11C,NRP2,BID,KSR1,DST,MTMR2,CALB2,CABP7,SLC25A14,CARS,CBS,USP2,SYNGR3,DGKI,SEPT7,ZBED1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,NDST3,NRXN3,FAM189A2,QKI,MAP4K4,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ZNF521,ZFP28,SLC35F1,CLOCK,GDA,OSBPL3,CSNK1G3,GREB1,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TBC1D5,MATR3,KCTD8,MAML1,YTHDC1,JAKMIP2,ALKBH8,PLPPR4,SACS,SPOCK3,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,DMTF1,SLC12A6,PDCD6IP,DTNB,MAMLD1,DNM1L,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,DCTN4,EPB41,EPB41L2,LRRC17,STX2,DENND4A,EXTL2,ABCA8,SH3YL1,SCML2,GORAB,POLR1B,AMOTL2,PRKAG2,SCARA3,MEX3B,SYNCRIP,RGPD5,UFM1,FAM49B,ATP6V1H,KHDRBS3,NSG1,MSANTD4,OGA,ZMAT1,CHL1,TRAF3IP2,IP6K3,ERAP1,KIAA1841,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,TNRC6A,GNAO1,ADGRA3,PRUNE2,TDRKH,GRB10,GRIA2,CIT,FAM19A2,GUCY1B1,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,SMAP1,C2orf72,SOWAHA,ZNF678,FAM69A,LRRTM1,STXBP5,LAMP2,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,CHIC1,MEIS2,MID1,PPM1L,ADAM22,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,ZNF827,PCDH9,PDE4D,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,TMEM260,PTPN13,PPP2R3C,USP47,OXR1,REV3L,PRRT2,ERI2,FIGN,SETD5,EXD2,CARF,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN8A,SUPT20H,FRMPD1,ARX,KIF16B,CPEB3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,FAM81A,KANSL3,PKNOX2,TET1,ZFP1,RCOR3,TTC17,LIMCH1,SNRPN,TMCC1,MYO16,BDP1,DOK5,KDM3A,SP4,HECW1,RBM26,SPART,CLASP2,SSTR1,SSTR2,NKAIN2,STAU1,ZSCAN29,NEK4,RGL1,STXBP1,SYPL1,COBL,CAMTA1,MCF2L,ADGRL3,DMXL2,SATB2,USP22,CLASP1,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,SLC44A1,ACTR6,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,DCBLD1,ANKRD20A2,SSBP2,CCDC14,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,SLC30A4,MAP3K12,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,HNRNPA3,PHTF2,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-519a:mirSVR_highEffct hsa-miR-519a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-129 1.22E-125 2.35E-127 2.16E-126 289 1430 "KCNH8,NCKAP5,ADCY6,GALNT13,SLC24A4,ZNF608,HFM1,SPARCL1,SRPX,ABCD2,ARHGAP20,OGT,LRCH2,SEMA7A,EP400,LINC00173,STK33,RASL11B,SLC4A4,ATP2A2,ZNF583,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,HIP1R,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,ABCG2,IGLON5,SLC4A8,RCHY1,AHCTF1,FAM171B,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,PITPNM3,UBXN2A,PHF14,PPP6R2,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,MYEF2,FBXL5,PLPPR4,SACS,WDR20,DMD,USP3,CPEB2,DPYSL2,DNAJB6,DNM1L,EBF1,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,CALCRL,CEP85L,RASL12,EZH1,ACSL4,TAOK3,CEP78,SLC9B2,PRKAG2,MEX3B,FOXF2,RGPD5,JKAMP,NBEA,UFM1,TPK1,ATP2C1,GABBR1,B4GALNT1,ERAP1,DISC1,SULT1C4,ZNF276,TOX3,ZNF638,LUZP2,GNAL,GRB10,DIDO1,CIT,RNF165,RABL2A,PSIP1,GUCY1B1,HAS2,FRMD3,MIER3,IRF8,LRRCC1,ZNF678,FAM69A,KCND2,KCNN2,CREG2,KIF5A,LIG4,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,LRP1B,MID1,MITF,XRRA1,MSR1,LAYN,MYT1,NACA,NELL2,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,OCRL,GPR137C,CNTN3,GNG2,FAM218A,CCSER2,TMEM38A,JAKMIP1,SCHIP1,EPB41L4B,PPM1B,PPP2R5E,PPP3CA,PKIA,MASP1,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTPRB,ACSM5,ZSCAN2,QDPR,PID1,CEP97,SLC25A48,USP47,OXR1,RBBP6,ZDHHC14,TRIM68,RET,RFX3,SLC25A36,RNASEL,ZFHX4,CCDC82,SETD5,PNMA8A,ROBO1,RORB,ZNF671,RTN1,RYR3,SALL1,CSRNP3,PRCD,SCP2,HSPA4L,ARX,KIF16B,CPEB3,SHC4,CHD9,SYBU,FAM81A,CCDC88A,BTBD7,RCOR3,ANKRD36,KIF13A,CMTR2,SNRPN,TMCC1,USP33,TRERF1,DOK5,HECW1,TEX2,IQSEC2,SPART,CLASP2,TROVE2,POGZ,ITPRID2,LARP4,ERBIN,ADHFE1,NECAB1,PLCB1,SYT1,ANKRD12,PJA1,CAMTA1,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,AKTIP,SLC44A1,THRA,TLR4,R3HDM1,STXBP4,TSC1,UBC,FAM155A,UBE3A,FLRT2,VLDLR,TBC1D15,XPO1,PCDH20,ZBTB14,ZNF711,ZNF45,ZNF74,MKRN3,TCEAL7,REEP1,FSTL5,ANKS1B,MAP3K12,MFF,FAM47E,WNK3,PLSCR4,RGS7BP,SMIM8,PHTF2,CASC15,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-1305:mirSVR_highEffct hsa-miR-1305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.62E-129 1.46E-125 2.75E-127 2.53E-126 329 1871 "KLHL32,GALNT13,ADD2,SLC24A4,KCTD16,HACE1,OSBPL6,CC2D2A,TAOK1,SPOP,CEP126,ABCD2,MARCH4,PCDH10,FAM135A,LRCH2,LCORL,TNRC6C,RGS20,ZSCAN18,ZBTB10,NCOA1,NUMB,STX16,ADAM23,BACH1,SEC11C,PROM1,DST,SYNJ1,ST3GAL5,ARHGEF7,NAE1,MTMR2,JAZF1,SGCE,CA8,ZNF555,KALRN,PTBP2,CAMK2A,RUNX1T1,CLDN10,RGN,MTMR7,C1orf52,MAGI1,TIGD7,CCPG1,NDST3,SLIT2,RAB33A,QKI,ARMC8,LETMD1,ABI3BP,RCHY1,AHCTF1,RTTN,ZFP28,CNRIP1,CLOCK,PREPL,CREM,HAPLN1,GDA,SUSD5,PDE4DIP,PLXNA4,ERC2,APPL1,UBXN2A,PHF14,PUM1,RIMS2,DOCK4,ZFYVE16,ZNF337,KIAA0586,PABPC5,ARMCX4,ARMCX2,SPATA2,JAKMIP2,ZNF804A,ZBTB24,MYEF2,ZC3H11A,ALKBH8,RHOBTB1,SACS,SPOCK3,CPEB2,DPP6,PDCD6IP,DTNB,DNM1L,GOLT1B,WDPCP,KLHL5,TMTC1,FAM13A,MBNL2,KCTD3,TENM1,STARD3NL,LRRC17,ENPP6,ZNF549,DNAJC27,ADGRV1,F8,CLVS1,TAOK3,GORAB,PRKAG2,SUCO,MEX3B,FOXF2,IQCG,SLC37A3,UFM1,FAM49B,CAMKK2,ATP6V1H,KHDRBS3,MSANTD4,OGA,CHL1,ZNF234,SIGLEC8,C15orf41,SEPT9,GATM,ALDH1L1,TUBGCP4,ARFIP1,GHR,PPARGC1A,MALT1,COPS8,ZNF638,ZNF782,LNX1,WDFY3-AS2,ATP2B1-AS1,GRB10,GRM8,BTN2A1,LINGO1,PSIP1,MAP4K5,MUM1,HAS2,PADI2,ZHX1,FRMD5,HMGCR,HNMT,CFAP126,USP51,ICA1,IFI16,SOWAHA,IL6R,IL12A,ZNF678,INPP1,NME9,CREG2,IPO5,STXBP5,CYP27C1,LIG4,HECTD2,NCOA7,MAP2,MAP4,MARK1,MBNL1,LRP1B,MEIS2,MITF,AFDN,MXI1,VWA2,NOVA1,NTRK2,CHAMP1,PCDH9,PRTG,PLCL1,SMIM7,TRHDE,STRN3,FA2H,SH3KBP1,CCDC144B,KANSL1,PRKACB,CEP41,PKIA,MAPK4,MAPK9,GRAMD1C,DCHS2,CNNM2,BCAS3,CNTLN,BDNF-AS,PTK2,PTPRO,TTC13,TMEM255A,RAD17,RBBP8,KHDRBS2,MSANTD2,TRIM68,ERI2,GTDC1,FIGN,RFX2,RFX3,ZFHX4,ZNF532,TMLHE,PNMA8A,CCDC102B,MRAP2,RPE,ATP8B4,TCP11L1,FAM161B,MEG3,ABCA11P,ATAT1,CLIP1,ZNF331,CCDC112,TRAPPC13,AP1AR,SALL1,SEMA6D,SCN7A,FNIP1,TNFRSF19,ZFP2,PPM1E,CHD9,FAM81A,PPP4R3A,SEPHS1,SLC12A2,TET1,CDK5RAP2,RCOR3,ANKRD36,CABCOCO1,CMTR2,SNRPN,USP33,UHRF1BP1L,CDK19,TROVE2,CLSTN2,NXT2,MPRIP,TTBK2,NUDT10,SYPL1,ANKRD28,C12orf76,PJA1,AGTPBP1,DMXL2,SATB2,RPGRIP1L,SZT2,PCDHB10,PCDHB9,PCDHB6,GPRIN3,PCDHA1,FRYL,RNF175,C18orf54,TMPO,TPM1,SYNPO2,RUNDC3B,TSN,SGK3,FAM155A,PLEKHH2,CCDC14,TBC1D15,P2RY12,LAT2,RICTOR,XPO1,PCDH20,ZIC2,ZNF32,TRIM9,ZNF540,MKRN3,LYPD6,REEP1,FSTL5,LAMP5,SLC30A4,EMSY,CADM2,LINC02210,STOX2,PRDM10,ADAMTS9,FIP1L1,PARP11,ST7,PHTF2,ADAMTSL3,JMJD1C,NLRP3,RNF170,FRMD6,GAN,CPNE4" MicroRNA hsa-miR-217:mirSVR_lowEffct hsa-miR-217:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.65E-129 1.48E-125 2.75E-127 2.53E-126 322 1791 "KCNH8,EMILIN3,KLHL32,ADD1,KIAA1211,RNF150,PTCHD1,BEND6,AP2A2,ZNF608,KIAA1324,TAOK1,SEMA6A,CEP126,UNC79,AMPD2,ZFAT,CCDC146,MYH7B,SUGT1P4-STRA6LP-CCDC180,VAT1L,USP37,CPNE5,LINC00173,CDK13,NUMB,SLC4A4,EIF4G3,ATP1B3,DPY19L3,ADAM15,BACH1,LINC00847,MPDZ,PROM1,FUBP1,SCAPER,CACNB4,CALB2,PTBP2,ISPD,KRIT1,SYNGR3,C1orf52,DCLK1,CFL2,NPIPA1,CHRNA4,QKI,SULT4A1,MAP4K4,CNN3,ARHGEF6,CNR1,AKAP7,IQCK,COL4A5,BAG4,ZNF521,SEC31B,CLOCK,C2CD2,NCOR1,GDA,TRIM69,CSF1,CSF2RA,SEC24C,CSNK1G3,VCAN,FAM169A,PPP1R16B,APPL1,PNPLA8,RIMS2,SEC14L5,BOC,KATNAL2,RIPOR2,LIN54,SPOCK2,ARMCX4,SPATA2,YTHDC1,ZBTB24,TIAM2,PLPPR4,EXOG,GRIN3A,USP3,CDON,PDCD6IP,ARRDC4,FAM78B,WDPCP,TMTC1,CELSR3,MRO,KMT5B,EIF5,IRAK4,TENM1,ELN,TMEM35A,CALCRL,PAN3,DCTN4,EMX2,EPHB1,RABEPK,MRPL10,ANKMY1,SIRPB1,KATNAL1,F5,CLVS1,FAM198B,RPS6KC1,FCGR3A,FECH,FER,GTF2IRD2,FGF1,FGF12,POLK,SUCO,UBE2E3,SEC23B,SYNCRIP,FLT1,NELFCD,POMT1,APOPT1,PDLIM5,TRIM16,ST6GALNAC3,STAU2,ZMAT1,MEGF10,B4GALNT1,RAPGEF6,IP6K3,ZNF559,DISC1,LRRC37A6P,ALDH1L1,MSTN,ARFIP1,PCDH17,LYVE1,TOX3,AIFM3,KDM2B,HTATSF1,PRRC2B,GPD1,GPD2,TDRKH,CACFD1,GRM2,GRM8,RNF165,ZBTB49,PSIP1,GUCY1A1,GUCY1B1,FRMD5,BACH2,AGFG1,SHISA6,ZNF546,RBPJ,KNDC1,TJAP1,SCIN,INPP1,METTL21A,KCNN2,CREG2,IPO5,PAXBP1,GPR155,AQP11,MATN2,MBNL1,MEF2C,MEIS1,KCTD6,MMP16,MN1,MXI1,RTL5,ZNF862,ZC3H12B,NNAT,CNOT4,OCRL,GLIPR1L2,PCSK5,ENPP2,PFKFB2,PIK3C2A,ZNF655,FAM218A,CCSER2,LRP12,ING3,SEPT4,POLG,PPARA,PRKAB2,EPDR1,GRAMD1C,HYDIN,CYBC1,APTX,CNTLN,ANKHD1,NCR3LG1,SPDL1,PTPRD,PTPRN2,ACSM5,CEP97,USP47,RAD51D,FAM66C,TRIM68,RET,SLC25A36,RIC8B,ZNF532,ROBO1,ELP2,ZC3H14,GLDN,STK32B,RYR3,SALL1,PRCD,PEAR1,SEC14L1,SCAF8,PPM1E,FERMT1,CHD9,NLGN1,NUBPL,ABLIM3,SLC2A5,SLC12A2,SMARCA4,SNAP25,SNCA,MBD5,USP33,FAM219A,TRERF1,BDP1,KDM3A,ZSWIM8,MYCBP2,CDK19,TSPYL2,LARP4,NKAIN2,ELOVL4,RGL1,ADHFE1,STX1A,SEPT3,SYN2,SYT1,ANKRD28,TACC1,TACR1,PJA1,CAMTA1,MCF2L,TAF9,FAM208A,KIAA1107,SMG6,MGRN1,DMXL2,TPCN2,CLASP1,DOCK9,FRYL,SIK3,TEK,ITGB3BP,AKTIP,ARL10,ERCC6L2,TMPO,R3HDM1,TPM2,C9orf85,TTC3,UCHL1,UGT8,BCL2L13,TBC1D15,CLDND1,GUSBP1,ZNF24,LYPD6,FSTL5,EML6,MAP3K12,ZXDA,RNF103,TRIM16L,UBE3B,PHTF2,CASC15,TIGD6,KLHDC1,FRMD6,SOCS4,ST8SIA2" MicroRNA hsa-miR-16-1*:mirSVR_lowEffct hsa-miR-16-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.63E-129 4.83E-125 8.78E-127 8.08E-126 336 1960 "CLK4,KLHL32,AXIN2,INTS2,PCDH19,HACE1,OSBPL1A,CC2D2A,C1QTNF3,SEMA6A,CEP126,GPRASP2,ZNF687,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,DDO,PPP4R4,CASK,SPTBN4,NCOA1,DPY19L3,TTLL9,BACH1,ADGRB3,NRP2,DST,SYNJ1,FUBP1,BTK,AP1M1,GYG2,C5,RAB29,WASF1,LDLRAD4,CACNB4,CALB1,CAST,CBS,CCNH,CDH2,ZMYM4,MAGI1,TIGD7,CCPG1,RCBTB2,SRSF11,CHN2,CNOT8,C4orf33,AKAP7,COL4A5,MYRIP,ZFP28,NRG2,RBM39,HAPLN1,ANKRD44,GDA,LRRC3B,OSBPL3,VCAN,SOCS5,APPL1,PUM1,RIMS2,ZSCAN23,CYBB,BOC,DOCK4,GAPVD1,RIPOR2,ZFYVE16,LONRF1,KCTD8,DGKB,DAPK3,PITPNC1,YTHDC1,MYEF2,KIAA0319,KLHL3,SNAP91,SPOCK3,WDR20,FAM107B,SEC16A,CHRDL1,DNM1,CDON,DOCK2,DPYSL2,ARRDC4,DUSP9,E2F5,EDNRB,TMTC1,FSD1L,TENM1,RGS17,PCOLCE2,STARD3NL,CALCRL,EPB41L2,LRRC17,DENND4A,IGSF6,ZNF549,APC2,FAM198B,DLC1,CEP78,SLC9B2,MED12L,FGFR1,MAD2L2,POLK,UBE2E3,MEX3B,SYNCRIP,SEMA4D,NELFCD,TMEM107,SMC2,UFM1,PDLIM5,FAM49B,ATP6V1H,ATP2C1,KHDRBS3,CSPG5,MEGF10,GABRB3,GABRG2,DISC1,ACSS1,KIAA1841,ALDH1L1,MSTN,WASHC2A,AHDC1,DCLK2,GPD2,TDRKH,LPAR4,GPR34,GRIA2,RNF165,ZBTB49,IRAK3,ELOVL5,HNF4G,HNMT,AGFG1,TCEAL6,DHX35,HSF2,IGF1,GAREM2,SLC35G1,KCNK3,GATD1,CREG2,CYP27C1,LIFR,HECTD2,LSS,CLEC18A,MAP2,MAP4,LYPLAL1,MBD1,LRP1B,MEF2C,KCTD6,PPM1L,AFF1,MSI1,MSR1,HS6ST3,MYO5A,MYO9A,NEXMIF,BEX5,ZC3H12B,NEK1,CNOT4,NOVA1,NTRK3,NUCB2,PDE4A,PDE4D,GPR85,PFKFB2,PFKFB3,ABCB1,NALCN,PIK3R1,CCSER2,GPSM2,FAM216A,MTRF1L,LRP12,SCHIP1,ING3,RETREG2,MINDY2,PPM1B,CCDC144B,PPP2R2B,RANBP3L,GDPD1,SNRK,CNTLN,PTN,ZIK1,PEX2,ZSCAN2,ZNF615,TUG1,TMEM255A,FAM66C,NWD1,ZCWPW1,ZNF493,RASGRF1,RADX,KHDRBS2,TRIM68,REV3L,GTDC1,NUDT11,CARF,ROBO1,PCMTD2,CCDC102B,RPE,ZC3H14,ADAL,TCP11L1,RPS20,ATAT1,RTN1,ZNF568,DGLUCY,SATB1,SCN2B,SCP2,MRAS,TRA2B,SCAF8,SH3BGR,PPM1E,CHD9,FNDC3A,ABLIM3,PPP4R3A,KANSL3,ZNF430,RADIL,ARHGEF40,CCDC88A,ELMO2,TET1,CPEB4,ZNF667,LIMCH1,SNCA,DOP1A,PDZD2,GLT8D1,UHRF1BP1L,SPP1,TEX2,PEG10,CDK19,RBM26,LMO3,NKAIN2,CEP68,ADHFE1,NECAB1,PRRC2C,ARHGEF9,NUDT10,SYT1,MCF2L,TAF9,DNMBP,PDLIM2,ADGRL3,DMXL2,SATB2,TRIM2,DOCK9,CRTC1,RNF216P1,PMS2CL,AKTIP,SLC44A1,TIAM1,TLR4,ERCC6L2,TMPO,BEX4,TPM1,C9orf85,STXBP4,TSN,TTTY15,CLHC1,FLRT2,PLEKHH2,CCDC14,XRCC4,MICU3,CELF4,ZBTB38,PRTFDC1,SLC38A1,MDH1B,PLSCR4,PARP11,DNAH10,FAM13C,SMIM8,FBXO36,JMJD1C,RNF170,ZDHHC20,NETO2,RNF146,SOCS4,CPNE4,SPATA13" MicroRNA hsa-miR-548k:mirSVR_highEffct hsa-miR-548k:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-128 8.56E-125 1.53E-126 1.41E-125 312 1689 "RALGAPA1,FMNL2,TMCC3,PWWP2A,OLMALINC,ZNF608,KLHL13,OSBPL8,CC2D2A,HFM1,TAOK1,ALCAM,ABCD2,MARCH4,AMPD3,AMPH,OGT,LRCH2,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,VAT1L,PPP4R4,CDK13,ZBTB10,ATP1B3,ZNF583,DOCK11,ADGRB3,BBS2,MPDZ,SEC11C,BMP7,ARHGEF7,FUBP1,SCAPER,C5,WASF1,CACNA1B,KALRN,METTL6,C1orf52,LRRFIP1,L3MBTL4,CFL2,RCBTB2,CHN1,B4GALT6,LHX2,QKI,CNN3,CNTN1,ARMC8,COL4A5,COL9A1,SLC4A8,ABI3BP,AHCTF1,CRHBP,ANKRD44,GDA,CSNK1E,CSNK1G3,SIPA1L1,VCAN,ERC2,ZSCAN23,RIPOR2,ARHGAP24,HDAC4,LIN54,MATR3,PABPC5,GIT2,PITPNC1,YTHDC1,KIAA0753,ZC3H11A,DDX46,PLPPR4,SACS,SV2B,DYNC1I1,DOCK2,DPYSL2,SLC25A18,PDCD6IP,ABCC5,GOLT1B,WDPCP,EDN1,EDNRB,ANKRD46,RASGRP1,SEMA3D,FSD1L,MBNL2,KMT5B,AASS,COPS4,TENM1,C8orf37,PAN3,DCTN4,COQ7,CEP85L,ZNF549,EXTL2,ABCA8,ACSL4,SCML2,CEP78,CHST15,FCGR3A,KAT8,GTF2IRD2,FGF13,POLK,MEX3B,ATP13A4,FLT1,JKAMP,NBEA,CSPG5,MSANTD4,ZMAT1,TRAF3IP2,RAPGEF6,ERAP1,C15orf41,KIAA1841,IGSF5,SESN1,ADAM28,CRCP,RNPS1,TNRC6A,ZNF638,LUZP2,RAB40B,WDFY3-AS2,ADGRA3,GPD2,PRUNE2,GPR12,GRIA2,FAM19A2,COQ10A,BVES,AP4S1,PSIP1,ADAMTS6,MAP4K5,MIER3,HSF2,CELF5,EID2B,NKD1,RBPJ,JAK2,METTL21A,IPO5,LIMS1,NCOA7,SMAD1,MARK1,MBD1,MBNL1,MEF2C,SRSF12,MIA2,KITLG,POC1B,ZNF680,THYN1,ZNF92,NFE2L2,NOVA1,SLC11A2,NRCAM,P2RY1,GPR137C,DPY19L2P2,PDE4B,CYTL1,FAM218A,CCSER2,ZFYVE21,RETREG1,PLCB2,PDZRN4,STRN3,LRP12,EXOSC10,LRRN3,PPP3CA,PRKACB,PRKCB,MASP1,CNTLN,SPDL1,PPP2R3C,ZNF793,ZNF493,RADX,ERI2,RGS3,SLC25A36,PBRM1,DCUN1D2,ALG9,CARF,GSTCD,ROBO1,RORB,MRAP2,RPE,LRRK2,MEG3,HUNK,RTN1,CCDC112,AP1AR,SEMA6D,SATB1,ATXN7,SEC14L1,FOXRED1,ARX,CHD9,WDR47,FAM214B,SEPHS1,CCDC88A,KBTBD4,NAPB,CPEB4,RCOR3,SNAP25,PDZRN3,PDZD2,SP2,SP4,UHRF1BP1L,KDM4C,CDK19,ZBTB43,RBM26,CLASP2,ITPRID2,SS18,CEP68,TTBK2,ZC3H4,VPS13A,MTCL1,CAMTA1,FAM208A,ADGRL3,AGTPBP1,TCEA1,DMXL2,SATB2,ZFP90,ZEB1,CLASP1,DOCK9,PCDHB9,PCDHB7,PUM2,FRYL,ZFPM2,ITGB3BP,AKTIP,ARL10,TIAM1,ASXL3,NR2E1,TMPO,CSMD1,RUNDC3B,TRPS1,TSC1,FAM155A,BCL2L13,XRCC4,PCDH20,ZFP37,ZIC1,ZNF711,ZNF708,MICU3,ZNF45,CELF4,ZNF142,ZNF189,EMSY,RNF103,WNK3,DNAH10,FAM13C,KAT6A,HNRNPA3,PHTF2,ACTR3B,FAM219B,ADAMTSL3,JMJD1C,KLHDC1,IFT88,CPNE4" MicroRNA hsa-let-7b:mirSVR_lowEffct hsa-let-7b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-128 1.54E-124 2.70E-126 2.48E-125 334 1944 "AS3MT,GALNT16,GALNT13,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,CDC42BPA,LCORL,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM23,ADAM15,MPDZ,CACNB4,PTBP2,CAST,NFS1,USP6,SLC16A4,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,CACNA2D2,ASIC3,MS4A7,CNOT8,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,CLIP3,TRIM69,ABCG1,CS,RGS6,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,MYEF2,MFAP3L,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,ACOT8,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,VPS13B,EPB41L2,COQ7,EPHB1,RABEPK,NCALD,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,FGF1,HPCAL4,IP6K2,FLT1,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,IP6K3,SIGLEC8,DISC1,KIAA1841,GHR,PPARGC1A,LYVE1,RUNDC3A,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,LINGO1,ATOH8,HAS2,HLF,HMGCL,ZDHHC15,LRRC75A,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,INPP5B,SLC35G1,KCND1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,MYO9A,ZC3H12B,SFR1,NEFM,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,OXTR,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PLCB2,PURG,TRHDE,MAPKAP1,SCHIP1,RANBP3L,PRKACB,MAPK4,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,SPIN3,KIAA0895L,TCP11L1,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,FOXRED1,HSPA4L,CPEB3,ST6GAL1,ANKRD6,WDR37,BTBD3,EPN2,FAM214B,SLC6A8,ATF7IP,CPEB4,MAST1,SMARCD3,MYH15,IFT122,INAVA,FAM126B,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,TSPYL2,MCF2L2,RBM26,DDN,NFASC,POGZ,ITPRID2,SSTR2,ST5,PLCB1,FAM208A,PDLIM2,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,DICER1-AS1,AP4E1,ARL10,TIMP4,ERCC6L2,PIK3R5,NPL,C9orf85,WBP2,CHST5,SMUG1,ELP5,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,MICU3,ZNF28,ZBTB38,MEIS3,ZNF225,FIP1L1,TRIM16L,CASC15,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-574-5p:mirSVR_lowEffct hsa-miR-574-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.10E-128 4.53E-124 7.82E-126 7.20E-125 317 1755 "VWA5B2,RALGAPA1,ABCF1,KCNH8,ABR,CLK4,ABHD6,SYS1,GALNT16,GALNT13,UNC5A,KCTD16,OSBPL1A,KIAA1324,ZNF578,FAM135A,ANK2,SEMA7A,C6orf89,MAP4K3,PHYHD1,CDK10,IGDCC4,TMEFF1,CADPS,MARK4,CCDC74A,NCOA1,NUMB,ATP1A1,RNF182,N4BP2L1,ATP6V0A1,LINC00847,BCS1L,NRP2,CFLAR,ARHGEF7,CASTOR3,WASF1,CACNA1B,DDR1,CACNB4,LURAP1,CLDN10,METTL6,RGN,P2RX6,CBFA2T2,LOC730101,CACNA2D2,FOXN3,SLIT2,RAB33A,VAX2,QKI,MAP4K4,ARHGEF6,FAM149A,ABI3BP,IGDCC3,CDC42BPB,CREM,ENTPD4,CRMP1,CLIP3,SNCAIP,CSF1R,ARHGEF10,PHACTR3,CST3,PLXNA4,KIAA0040,PUM1,ZSCAN23,RUBCN,SEC14L5,DOCK4,GAPVD1,ZFYVE16,EARS2,LONRF1,TBC1D5,TMEM170A,SPATA2,HEPH,KIAA0753,TMEM130,SNAP91,SV2B,CHRDL1,DMD,CDON,SLC12A6,DPH1,PDCD6IP,DTNA,DTNB,MAMLD1,DNAJB6,EDNRB,TMTC1,FAM13A,EGR3,STARD3NL,EPB41L2,EPHB1,RABEPK,SRRM1,CEP85L,SPEG,ETV1,VPS26C,SIRPB1,KATNAL1,ADGRV1,MRVI1,EZH1,NRN1,F5,TAOK3,RACK1,GORAB,SEC24B,GTF2IRD2,FGF1,SUCO,PCYOX1,AGAP2,SYNCRIP,SEMA4D,FLT1,ANKFY1,NELFCD,C2orf88,NBEA,FAM49B,ZNF605,CGREF1,MSANTD4,HHIPL1,TVP23A,MEGF11,HRASLS5,MTHFD2,C15orf41,DISC1,ACSS1,ADAM28,GFRA2,MALT1,TCERG1,COPS8,LUZP2,GPD2,GPR12,GRB10,DIDO1,PLPP7,ADAMTS13,ZNF496,RNF165,GSTT2,BVES,GUCY1A1,NXPH3,HLF,SYNPO,NEGR1,TCEAL6,HSPA1L,IDH3B,NKD1,KNDC1,INPP5B,NME9,JAK2,KCNJ16,KHK,KIF2A,A1BG-AS1,PAXBP1,SYTL4,NCOA7,MAP2,MAP6,MARK1,LYPLAL1,ADAM11,MEF2C,MEIS1,POC1B,MMP16,ZNF680,BLOC1S2,NRBP2,MYO9A,MYT1,NEK1,CNOT4,DNHD1,NTRK2,CNTN3,PAX6,ETFRF1,PDE1C,PDE4D,ENPP2,OLA1,FAM216A,MTRF1L,PLXNB1,PSAT1,SCHIP1,POLR2F,PPM1B,PRKACB,MAPK4,HYDIN,DIRAS2,SAMD9,BCAS3,SNRK,QRICH1,PTX3,NKAIN1,SLC25A48,CCDC40,SH3TC2,FAT4,NWD1,RAP1GDS1,RASGRF2,RBBP6,GTDC1,RGS3,GLDN,MEG3,KCNIP1,STX1B,FAM192A,DGLUCY,STUM,TRA2B,KIF21A,SH3GL3,PPM1E,ARX,FHOD3,ARHGEF40,BTBD7,SLC22A4,MBD5,SNRPN,MYO16,TRERF1,NMNAT2,MYCBP2,PEG10,ZC3H13,SPTAN1,IQSEC2,TSPYL2,RBM26,NXT2,MPRIP,DIP2A,KANK1,SEPT3,SYT1,COBL,ASTN2,SYT5,TACC1,TACR1,IQCE,FBXW11,MGRN1,TCF12,SYNE1,NAT16,USP32P1,GPRIN3,PCDHA5,DNAH7,DICER1-AS1,TIAM1,RIMBP2,CSMD1,CHST5,TSN,TTC3,OSBP2,FLRT2,PLEKHH2,USP1,WIPF1,P2RY12,CLIP2,CLDND1,ZNF540,ZNF70,MKRN3,MAP3K12,SLC38A1,PRDM8,SEMA3B,MDH1B,FZD3,MARCH8,PHTF2,FAM219B,JMJD1C,FXR1,NETO1,CPNE4,PRRT4" MicroRNA hsa-miR-129-5p:mirSVR_highEffct hsa-miR-129-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.13E-127 6.32E-124 1.07E-125 9.86E-125 317 1757 "AS3MT,NCKAP5,ACTN1,XKR4,NDRG3,KLHL32,ADD1,ADD2,PWWP2A,PTCHD1,ZNF608,PCDH19,WDR35,AK2,TAOK1,ADGRF5,SEMA6A,SPOP,ABCD2,AMPH,CDC42BPA,ANK2,CCDC146,PHF12,APC,TMEFF1,ARNTL,MARCH3,ZBTB10,NCOA1,EIF4G3,ATP2B2,RNF182,ADAM23,TTLL9,BACH1,ADGRB3,SEC11C,BCHE,CACNA1B,CACNB4,CALM1,VXN,RUNX1T1,CBFA2T2,LRRFIP1,MAGI1,DLGAP2,TIGD7,NOG,LHX2,DGCR9,QKI,LY86,CNN3,CNR1,ARMC8,SMARCAL1,NRG2,ZNF385A,SEC31B,PREPL,CREM,GDA,TRIM69,LRIG1,CSNK1E,SIPA1L1,VCAN,CNTNAP2,KIAA0040,PHF14,RIMS2,USP6NL,HDAC9,GPRASP1,GAPVD1,TCAF1,ARHGAP24,ZFYVE16,KIF26A,LIN54,MATR3,KCTD8,PABPC5,MYEF2,TIAM2,ZC3H11A,DDX46,PLPPR4,SPOCK3,USP3,NR1D2,SLC25A18,PDCD6IP,DTNA,DNAJB6,ABCC5,GOLT1B,EBF1,EDN1,ANKRD46,CNNM1,KLHL5,FSD1L,EGR3,AASS,DCTN4,VPS13B,EPHB1,GPHN,SRRM1,CEP85L,ETV1,NRN1,CLVS1,FAM198B,TMEM132C,ACSL4,TAOK3,DLC1,GORAB,MED12L,FGF12,FGFR1,AMOTL2,PRKAG2,FHL1,SYNCRIP,JKAMP,KHDRBS3,CELF1,CSPG5,MEGF11,HRASLS5,GABRA3,ERAP1,ZNF559,C15orf41,DISC1,MSTN,GFRA2,PCDH17,GHR,GLYR1,TNRC6A,ZNF638,CBX1,KDM2B,GNAO1,FERMT2,TDRKH,LPAR4,GPR37,TMEM121B,PCLO,PLCD4,SERP2,GRM8,LINC01089,GSN,RNF165,FRMD3,BACH2,MIER3,HNF4G,IRF8,FAM95B1,RBPJ,KCNB1,STXBP5,CYP27C1,SYTL4,HECTD2,MAP2,MATN2,MBNL1,EFHB,TM6SF1,LRP1B,MEIS1,MEIS2,MMP16,COL28A1,MYO9A,MYT1,NDP,NFE2L2,SLC11A2,NRCAM,SMIM11A,NTRK2,OCRL,OXTR,PAX6,PCDH9,PCSK5,ABCB1,NALCN,ZNF655,CCSER2,RETREG1,PLCL1,SLC25A23,MTRF1L,PDZRN4,LRP12,ING3,EPB41L4B,SH3KBP1,MINDY2,LRRN3,PPP2R5E,PPP3CA,PRKCB,MASP1,SAMD9,CNTLN,PTN,TMEM260,PTPN13,USP47,RAD17,ZNF793,NWD1,OXR1,RET,ERI2,FIGN,SLC25A36,RIC8B,RORB,NEK11,FBXW7,ATP8B4,MAP6D1,KCNIP3,TRAPPC13,ATXN7,SCN8A,SCP2,SEC14L1,NLGN1,SEPHS1,CCDC88A,BTBD7,ATF7IP,SLC22A4,TET1,LIMCH1,SNCA,MBD5,SNRPN,SOX3,SP2,SP4,NMNAT2,MYCBP2,KDM4C,ATP10B,POGZ,SAMSN1,SSTR2,ZC4H2,NKAIN2,ERBIN,NXT2,TTBK2,ADHFE1,KLHL7,NUDT10,SYT1,CAMTA1,TAL1,ADGRL3,TCF4,RPGRIP1L,SYNE1,PCDHB3,FRYL,ZFPM2,GPR161,ARL10,BHLHB9,ERCC6L2,LRRC8A,KAT6B,TP53BP2,CHST5,SYNPO2,TRIO,TRO,SGK3,RPL7L1,FAM155A,TBC1D15,RBFOX3,XPO1,XRCC4,ZIC2,TRIM9,ZNF74,CELF4,REEP1,FSTL5,ANKS1B,SPIRE1,UPF3A,ZXDA,EMSY,STOX2,KCNAB1,EPM2A,DNAH10,TRAM2-AS1,GAN,JPH3" MicroRNA hsa-miR-454:mirSVR_highEffct hsa-miR-454:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-127 8.31E-124 1.39E-125 1.28E-124 300 1570 "RALGAPA1,CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,BEND6,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,ADGRF5,ALCAM,SRPX,ABCD2,FAM135A,LRCH2,LCORL,APAF1,APC,LINC00173,STK33,NCOA1,STX16,ZNF583,N4BP2L1,DPY19L3,ADAM23,TTLL9,ADGRB3,NRP2,DST,C5,CABP7,THSD7A,KALRN,CAMK2A,CAST,RUNX1T1,USP6,SEPT7,TIGD7,CFL2,PLAA,CLTC,SRP14-AS1,CNR1,AKAP7,ARMC8,FAM149A,AKAP6,CLOCK,CREM,GDA,CSF1,RGS6,LRIG1,SIPA1L1,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,GREB1,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,HDAC9,DCAF8,ZFYVE16,LONRF1,DAPK1,SPATA2,YTHDC1,ELMSAN1,FBXL5,KIAA0319,RHOBTB1,SPOCK3,WDR20,RAB39B,DPYSL2,ABCC5,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,FAM13A,KMT5B,EGR3,ASB3,CERCAM,PAN3,DCTN4,ENPP6,RABEPK,SRRM1,CEP85L,RASL12,ACSL4,GORAB,FER,MED12L,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,PSD2,NELFCD,NBEA,TPK1,ATP2C1,FYB1,MEGF10,GABRB3,B4GALNT1,ERAP1,ARFIP1,SESN1,ADAM28,RAB30,TNRC6A,MSL3,KDM2B,MAP7D2,RAB40B,FERMT2,PRUNE2,GPR34,GRB10,PLCD4,CIT,RNF165,BACH2,HNMT,IRF8,ZIC5,LRRCC1,ZNF678,KCNN3,CREG2,IPO5,LIG4,LIMS1,MAP4,MARK1,MATN3,MBNL1,LRP1B,MEIS1,MEIS2,LYRM9,ZNF862,MYT1,NELL2,CNOT4,DNHD1,OCRL,OPA1,LOC100128398,GPR137C,PCDH9,PCSK5,PDE1C,GPR85,PFKFB2,CCSER2,JAKMIP1,PURG,LRP12,SCHIP1,PPP3CA,PSD,MTMR10,PTPRG,PID1,CEP97,RAD17,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,SLC25A36,CCDC82,ZNF532,SETD5,KLHDC8A,CARF,GSTCD,ROBO2,EPHA10,ATP8B4,LRRK2,CLIP1,RTN1,CCDC112,LRFN5,PEAR1,ARX,KIF16B,CHD9,SYBU,SEC31A,BTBD3,WDR47,SEPHS1,SLC8A1,CCDC88A,SLC14A1,BTBD7,ZNF667,SNAP25,SNCA,KIF13A,USP33,TRERF1,BDP1,DOK5,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,ITPRID2,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,FBXW11,WSCD1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,SLC44A1,BHLHB9,ERCC6L2,R3HDM1,CSMD1,TNS1,SMUG1,STXBP4,TSC1,UBC,RPL7L1,FAM155A,UGT8,CCDC14,WRN,CFAP298,ZNF711,ZNF74,SPHK2,TCEAL7,ZBTB38,REEP1,FSTL5,SMARCAD1,MAP3K12,MFF,STOX2,KCNAB1,WNK3,PLSCR4,RGS7BP,MARCH8,UBE3B,PHTF2,NHSL1,FXR1,FRMD6,SENP7" MicroRNA hsa-miR-455-3p:mirSVR_lowEffct hsa-miR-455-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-127 1.30E-123 2.13E-125 1.96E-124 312 1705 "ASPHD1,CLK4,GALNT16,ADCY6,ADD1,PWWP2A,KIAA1211,ESYT2,AP2A1,AP2A2,OSBPL1A,OSBPL6,OSBPL8,CC2D2A,AK2,SEMA6A,ABCD2,FAM135A,SYT13,ZNF687,AMPD2,LCORL,SUGT1P4-STRA6LP-CCDC180,APBA2,FAM131A,TNRC6C,PPFIA3,CASK,CDK13,PDE8B,MARK4,PCDHGB4,NUMB,RASL11B,TMEM108,EIF4G3,ALDH7A1,ADAM23,TTLL9,ADAM15,ADGRB3,LINC00847,BBS2,RGS9,ARHGEF7,BTK,CA4,PTBP2,CAMK2A,CARS,METTL6,MTMR7,SCARB1,SYNGR3,CD38,CDH2,ARHGAP33,LRRFIP1,UBE2L6,CACNA2D2,ASIC3,CHN2,RAB28,NRXN3,CNTN1,COL4A5,TBPL1,COX4I1,AHCTF1,BAG4,SLC35F1,SEC31B,AKAP12,CRY2,HINFP,NCOR2,GDA,CSNK1E,VAC14-AS1,PPP6R2,ARHGAP32,KATNAL2,DCAF8,CENPL,EARS2,ZNF337,DAPK1,SPOCK2,DNAL1,ARMCX4,ARMCX2,SPATA2,SV2B,CHRDL1,DMD,DNM1,DNAH9,CD99L2,CDON,DRP2,PDCD6IP,E2F5,AASDH,EDNRB,HIPK3,HEYL,YAF2,PHF20L1,SUGP2,KCTD3,TUBD1,RABEPK,SPEG,MRPL37,CDKL3,CLVS1,FAM198B,DLC1,FCGRT,FDFT1,KAT8,PPP1R1B,ZNF589,SEC24B,OLFM1,FGFR3,MEX3B,WDR83,SPECC1,TPK1,CAMKK2,ZNF605,SARAF,OGA,MEGF10,GABRA3,IP6K3,LRRC37A6P,ALDH1L1,ADAM28,GGTA1P,PPARGC1A,MALT1,RUNDC3A,STARD3,LUZP2,LOXL3,GNAO1,FERMT2,ADGRA3,GPD2,STON1,GRB10,DIDO1,PLCD4,BTN2A1,DDX19B,HNMT,NEGR1,HSF2,LRRC75A,NKD1,GAREM2,TJAP1,ITPKB,KCND1,KCNN1,LINC00634,KIT,A1BG-AS1,PAXBP1,MEIS1,MEIS2,SRSF12,KITLG,BLOC1S2,MYO6,RTL5,NEFM,NEK1,NF1,NPTX2,NTRK2,NTRK3,TREM2,PCDHGC3,PCDH9,GPR85,GNG2,ZDHHC8,NLE1,PNMA3,SCHIP1,NKAIN4,RANBP3L,PRKAB2,PKIA,DCHS2,BCAS3,GDPD2,QRICH1,PIGG,PTN,TMEM260,PTPRB,PTPRD,PTPRG,PTX3,TUG1,USP47,RAD51D,IQSEC3,FAT4,RASGRF1,TRIM68,FIGN,KLHL11,RNASEL,SETD5,ARMC5,ROBO1,NEK11,ARMH4,SPIN3,KCNIP1,MAPK12,PRCD,ZNF821,FOXRED1,FAM102A,FERMT1,SHC4,R3HDM2,DZIP1,NUBPL,SLC8A1,ELMO2,MBD5,FAM219A,TRERF1,GLT8D1,ZNF621,ITPRID2,SSPO,ZSCAN29,NEK4,SULF2,STXBP1,NSFL1C,SYN2,PJA1,PDLIM2,TCF4,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,DOCK9,FRYL,PMS2CL,DICER1-AS1,GALNT17,HEY1,ERCC6L2,TMPO,PIK3R5,WBP2,ELP5,RUSC1,TSN,TSC1,TTTY15,ZKSCAN5,FLRT2,VAV1,VLDLR,VSNL1,RICTOR,GUSBP1,SLC47A2,ZIC1,ZNF24,ZNF45,ATP6V0E2,ZNF154,REEP1,EML6,UPF3A,INTS3,ZXDA,NT5M,LINC02210,PRDM8,RNF103,VPS35L,NAV3,FBXO36,CASC15,MSRB3,NETO1,LAS1L,SPATA13" MicroRNA hsa-miR-1272:mirSVR_lowEffct hsa-miR-1272:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.21E-127 4.59E-123 7.41E-125 6.82E-124 330 1919 "XKR4,KLHL32,PSMG3-AS1,AXIN2,PLEKHH1,RNF150,INTS2,HECW2,PCDH19,KCTD16,OSBPL1A,NME5,KIAA1324,OSBPL6,WDR35,CC2D2A,SEMA6A,CEP126,PCDH10,SYT13,MAP4K3,SUGT1P4-STRA6LP-CCDC180,TNRC6C,USP37,CPNE5,LGR5,SHROOM2,PPP4R4,IGDCC4,ZSCAN18,SLC4A4,ATP6V0A1,MIR9-3HG,CFLAR,PROM1,BMPR1B,ARHGEF7,DDR1,CACNB4,LURAP1,THSD7A,ISPD,CBFA2T2,C1orf52,ZBED1,DCLK1,SOCS6,NRXN3,CLCN3,CLTC,QKI,AHCTF1,SMARCAL1,ZFP28,SLC35F1,CREM,CLIP3,SNCAIP,CSF1,RGS6,SIPA1L1,RIMS4,CNTNAP2,PLXNA4,PPP1R16B,ERC2,UBXN2A,PLCXD3,ZSCAN23,USP6NL,CCDC144A,KIAA0408,DOCK4,ARHGAP32,KATNAL2,EARS2,TBC1D5,KCTD8,DGKB,DGKG,DAPK1,ARMCX4,PITPNC1,ARMCX2,ELMSAN1,JAKMIP2,DGCR5,POM121,EXOG,GRIN3A,RAB39B,DMD,DNM1,SLC29A4,DMTF1,DPP6,PDCD6IP,ABCC5,SNX29,EDNRA,SEMA3D,FRY,FAM13A,MBNL2,KCTD3,EIF4G2,COPS4,TENM1,C8orf37,RCAN2,STX2,SRRM1,NCALD,IGSF6,ZNF549,ETV1,DNAJC27,SIRPB1,EXTL2,ADGRV1,F5,TUBA1B,FKTN,ZNF589,FER,FGF14,FGFR1,SUCO,SYNCRIP,FLT1,ANKFY1,NELFCD,WDR83,JKAMP,SMC2,TPK1,KHDRBS3,SARAF,DOT1L,OGA,MEGF10,GABRG2,FAM120B,GALC,CPLX2,GPR162,CYP46A1,PPARGC1A,ZNF638,HTATSF1,GPD2,FUT10,PLPP7,ZNF496,AP4S1,FAM107A,ADAMTS6,GUCY1A1,SLC2A6,VSIG4,HMGCL,ZNF491,ZDHHC15,CPT1C,TCEAL6,HSF2,FAM95B1,C2orf72,GAREM2,IL6ST,KCNN2,CREG2,KIT,STXBP5,CYP27C1,LIFR,LIMS1,SYTL4,GPR155,ZFYVE27,TM6SF1,MEIS1,MID1,MN1,BLOC1S2,HS6ST3,MXI1,BEX5,DNHD1,SMIM11A,GLIPR1L2,DPY19L2P2,PDCD2,GPR85,NALCN,PIK3R1,ZNF655,GPSM2,PRIMPOL,STRN3,LRP12,SCHIP1,MAGEL2,POLR2F,DRAM2,PPM1B,KANSL1,PRKCB,MAPK9,HYDIN,BCAS3,VPS13C,CYBC1,CNTLN,PTPRB,PTPRE,NKAIN1,ZNF793,SH3TC2,ZNF493,RDX,SLC25A36,DCUN1D2,C12orf49,ARMC5,PNMA8A,ROBO1,CCDC25,PGBD4,EPHA10,SPIN3,RPS6KA2,RYR3,ZNF331,FAM192A,SATB1,ATXN7,SCP2,SMPD3,GALNT10,ZFP30,PPM1E,FERMT1,FBXO11,ABLIM3,SLA,SLC8A1,SLC12A2,NAPB,BTBD7,SLC22A4,CPEB4,GKAP1,SMARCD3,RCOR3,ANKRD36,LIMCH1,KIF13A,LMBRD1,TRERF1,BDP1,FNBP1,PEG10,SPTAN1,CLSTN2,NKAIN2,STAU1,ZSCAN29,ELOVL4,DIP2A,STX1A,PRRC2C,RHBDL3,ARHGEF9,PLCB1,SYPL1,TACR1,ANKRD12,TAF9,KLHL4,TCF4,ZEB1,TPCN2,TRIM2,PCDHB9,SLC19A3,PCDHB7,OBSL1,USP32P1,HIF3A,FAM200B,DICER1,AP4E1,AKTIP,CDH22,FAM124A,RIMBP2,TPM1,TRPS1,PPIL6,TSN,SSBP2,CLHC1,HIRA,SGK3,ZNF709,LMF1,RICTOR,GUSBP1,ZNF23,ZNF24,ZNF28,ZNF45,ATP6V0E2,ZNF70,AMZ1,ZNF184,SMARCAD1,SLC38A1,PRDM8,KCNAB1,MPPE1,PARP11,FZD3,FBXO36,ADAMTSL3,TTC7A,FXR1,AP3B2,FAM198A" MicroRNA hsa-miR-205:mirSVR_lowEffct hsa-miR-205:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-126 7.45E-123 1.18E-124 1.09E-123 335 1981 "ABCF1,KCNH8,NCKAP5,RNF157,ADD1,AXIN2,ADORA1,ESYT2,ADRB2,PCDH19,NME5,WDR35,OSBPL8,C1QTNF3,PCDH10,FAM135A,SYT13,AMPD2,CDC42BPA,SEMA7A,C6orf89,PI16,PHF12,APBA2,PPFIA3,USP37,LGR5,PRX,IGDCC4,ZFYVE28,PDE8B,NCOA1,SLC4A4,SLC2A11,ALDH7A1,ADAM23,ADGRB2,ADGRB3,BARD1,SEC11C,BMPR1B,FUBP1,NAE1,MTMR2,SGCE,CA8,THSD7A,CALM1,USP6,MTMR7,C1orf52,LRBA,CDC25B,DCLK1,ZMYM4,L3MBTL4,LOC730101,DLGAP2,TIGD7,RCBTB2,TAOK2,RAB28,NRXN3,C4orf33,IGLON5,CNN3,AKAP7,FAM149A,AKAP6,SUMF2,ABI3BP,COX4I1,MYRIP,ZFP28,SEC31B,CDC42BPB,PREPL,CREM,ABCG1,SNCAIP,CSF1,CNTNAP2,PLXNA4,PUM1,RIMS2,RUBCN,GAPVD1,ZNF337,KCTD8,BRINP1,AIF1L,GIT2,ELMSAN1,JAKMIP2,ZBTB24,MYEF2,FBXL5,KIAA0319,ZC3H11A,EXOG,DMD,USP3,DNAH9,SLC29A4,DOCK2,DMTF1,ACOT8,PDCD6IP,ECM2,ABCC5,E2F5,EBF1,EDIL3,EDNRB,HIPK3,FRY,PHF20L1,RASA4,C3orf18,USPL1,LRRC17,STX2,SRRM1,ETV1,MRVI1,HSPA12B,PTK2B,CEP78,FDFT1,SLC9B2,FGF1,FGFR1,PRKAG2,FHL1,SUCO,UBE2E3,PCYOX1,VTI1B,SYNCRIP,WDR83,UFM1,FAM49B,ZNF605,CELF1,HHIPL1,AP4B1,OGA,GAD1,GALC,ZNF234,IQGAP2,ERAP1,MSTN,ADAM28,DBF4,LUZP2,FERMT2,WDFY3-AS2,GPD2,PRUNE2,MCHR1,GPR34,ATE1,CLASRP,KAT7,PSIP1,IRAK3,INSYN1,ARHGAP36,HNMT,NEGR1,LRRC75A,EID2B,ZNF181,IGF1,NKD1,ZIC5,KNDC1,SCIN,IL6ST,IBA57,INSM1,METTL21A,KCND2,KCNH2,KIF2A,STXBP5,KTN1,HECTD2,MAP6,MAT2A,CHIC1,TM6SF1,LRP1B,KITLG,PPM1L,POC1B,AFF1,AFDN,SAMD5,MX1,MYCN,LYRM9,MYO9A,NF1,NFYA,DNHD1,SLC11A2,NUCB2,OCRL,P2RX7,GLIPR1L2,PCDH9,PCSK1,FAM98B,ING3,RASGEF1B,MAPK3,GDPD1,RELN,GDPD2,CNTLN,PTCH1,BDNF-AS,MTMR10,SPDL1,STK32A,PTX3,CEP97,RAD17,SH3TC2,RASGRF2,GTDC1,LGI2,TMLHE,ROBO2,ELP2,CCDC102B,RPE,NEK11,ARMH4,ZC3H14,ATP8B4,RPS6KA2,HUNK,RYR3,TRAPPC13,AP1AR,RMI1,SCN7A,RASA3,PPM1E,KIF16B,CPEB3,FNDC3A,CNKSR2,FAM81A,PPP4R3A,LIMS2,KANSL3,PKNOX2,KBTBD4,SLC12A2,BTBD7,GKAP1,MBD5,SNRPN,PDZRN3,RBM34,KDM4B,FAM219A,BDP1,HECW1,MYCBP2,PEG10,TSPYL2,ITPRID2,ZC4H2,ELOVL4,NEK4,SEPT8,STXBP1,NSFL1C,SYNE2,CAMTA1,TBL1X,MGRN1,TRIM2,RPGRIP1L,USP22,FRYL,SIK3,FAM200B,ZFPM2,C18orf54,ITGB3BP,CDH22,ACTR6,CSMD1,KAT6B,C9orf85,ZNF346,TRIO,PDSS1,TRPS1,SGK3,LINC00689,PLEKHH2,BCL2L13,RBFOX3,CLIP2,ZNF781,GUSBP1,XPO1,ZIC2,ZNF24,LYPD6,ZNF154,EMSY,LINC02210,STOX2,PRDM8,FIP1L1,PLSCR4,RGS7BP,FZD3,DOCK8,RTN4,UBE3B,FBXO36,ACTR3B,NHSL1,IFT88,NETO1,SOCS4" MicroRNA hsa-let-7e:mirSVR_lowEffct hsa-let-7e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.45E-126 1.37E-122 2.14E-124 1.97E-123 335 1985 "AS3MT,GALNT16,GALNT13,PLEKHH1,UNC5A,OLMALINC,AP2A2,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,LCORL,PHF12,SHROOM2,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM23,ADAM15,MPDZ,CACNB4,CALM1,PTBP2,CAST,NFS1,ZNF501,USP6,SLC16A4,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,LARGE1,TIGD7,CLGN,ASIC3,MS4A7,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,CLIP3,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DMTF1,DPH1,PDCD6IP,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,CHST15,GTF2IRD2,FGF1,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,CAMKK2,ATP6V1H,ZNF605,ERGIC3,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,GSTM5,BVES,FICD,AP4S1,LINGO1,ATOH8,HAS2,TOX2,HLF,HMGCL,ZDHHC15,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,MYO9A,SFR1,NEFM,ALDH1L2,NME4,NOVA2,DNHD1,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,OXTR,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,ZNF655,PLCB2,PLXNB1,TRHDE,SCHIP1,RETREG2,RANBP3L,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,PTPRG,PTPRO,NKAIN1,SH3TC2,NWD1,ZNF493,RASGRF1,RASGRF2,ZDHHC14,GAL3ST4,TRIM68,KCTD17,ZNF532,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,KIAA0895L,TCP11L1,PTGR2,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,STUM,FOXRED1,HSPA4L,CPEB3,ST6GAL1,WDR37,BTBD3,EPN2,FAM214B,ATF7IP,CPEB4,MAST1,MYH15,IFT122,INAVA,FAM126B,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,KDM4C,TSPYL2,MCF2L2,RBM26,DDN,NFASC,POGZ,ITPRID2,SSTR2,ZC4H2,PLCB1,COBL,SLC37A2,FAM208A,PDLIM2,FBXW11,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,HIF3A,SIK3,RNF216P1,DICER1-AS1,AP4E1,ARL10,TIMP4,TK2,ERCC6L2,NPL,C9orf85,CHST5,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,ZKSCAN5,CLHC1,SLC35A4,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,ZNF708,ZNF28,EML6,MEIS3,EVI5,LINC02210,FIP1L1,TRIM16L,PARP11,FBXO36,CASC15,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-18a*:mirSVR_lowEffct hsa-miR-18a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.52E-126 1.97E-122 3.03E-124 2.79E-123 325 1870 "EMILIN3,XKR4,ADORA2A,KIAA1211,RNF150,PTCHD1,SLC24A4,PCDH19,KIAA1324,TXNDC16,ZNF578,CDC42BPA,ANK2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APLP1,DDO,PHYHD1,ARHGDIA,RGS20,ARRB2,LINC00173,CDK13,STK33,PCDHGB4,N4BP2L1,MYOM1,ADAM15,BID,CFLAR,ARHGEF7,MYRF,BAIAP3,CA8,KALRN,PTBP2,ARHGEF25,CBR1,P2RX6,ENTPD6,LRBA,LRRFIP1,LARGE1,RAB33A,MYL6B,FAM19A5,C4orf33,QKI,IGLON5,PICK1,IQCK,FAM149A,RCHY1,COX4I1,C2CD2,ENTPD4,SH2B1,ANKRD44,CSF2RA,SEC24C,SUSD5,RIMS4,CNTNAP2,PLXNA4,SLITRK5,RIMS2,PPP6R2,RUBCN,CYBB,HDAC9,MYADM,GIT2,DNAL1,ELMSAN1,B3GAT3,POM121,PLPPR4,DPH1,DRP2,RCAN1,GOLT1B,ANKRD46,HIPK3,FCF1,MBNL2,EGR3,GOLGA7,CERCAM,SRPK3,C3orf18,PAN3,DCTN4,EPB41,RASGRP2,NCALD,SPEG,ANKMY1,MRVI1,CLVS1,ZSCAN30,STRADA,GORAB,GTF2IRD2,FGF11,TMEM164,MAD2L2,SCARA3,HPCAL4,FOXF2,IP6K2,AGAP3,FOXO3,ATP13A4,WDR83,POMT1,TMEM107,SPECC1,ZNF605,ERGIC3,KHDRBS3,CGREF1,AP4B1,SDCBP2,MEGF11,GABBR1,SEPT9,GCNT2,GPR162,CYP46A1,SESN1,RUNDC3A,CRCP,RNPS1,MSL3,AIFM3,WDFY3-AS2,GPD1,GPD2,PRUNE2,LILRA2,PLCD4,PLPP7,GRIK4,CIT,CLASRP,BVES,RNFT2,ATOH8,NCKAP1L,VSIG4,HMGCL,IRF8,FAM95B1,C2orf72,RBPJ,DISP2,IL12A,ITGA7,GPR62,KCNH2,SYTL4,ASPRV1,CLEC18A,MAN2A2,MAT2A,MATN2,MBD1,MEF2C,MEIS2,AFDN,MPP2,NDP,SFR1,NELL2,NME4,VWA2,SLC11A2,TBC1D25,IGSF11,OCRL,P2RX7,ZNF827,PCDHGC3,PDE4B,PDE4D,PDE1B,PFKFB4,NALCN,SEMA5B,PIK3C2A,PIK3R1,ZNF655,GPSM2,PLEC,PNMA3,SCHIP1,FSD1,PPP2R5E,KANSL1,NKAIN4,PRKAB2,MAPK3,MAPK9,WBP1L,DEF8,PTN,ZSCAN32,PTPRG,PTPRN2,PTPRO,TUG1,TMEM255A,IQSEC3,NWD1,ZCWPW1,OXR1,RASGRF2,KIF7,LGI2,TMLHE,C12orf49,GSTCD,BAALC,KIAA0895L,GLDN,SATB1,ATXN7,SCN2B,SCN8A,PRCD,SEC14L1,GALNT10,STUM,FOXRED1,MRAS,TRA2B,COPZ1,SH3GL3,FERMT1,ASAP3,HKDC1,AMBRA1,CHD9,R3HDM2,CNKSR2,EPN2,PKNOX2,SLC6A8,SLC9A5,SLC11A1,SLC22A4,CXXC4,SMARCA4,SNRPN,ZSWIM8,NMNAT2,MYCBP2,ZNF423,SPTB,TSPYL2,NFASC,MESP1,LARP4,ZSCAN29,ADHFE1,STX1A,ARHGEF9,TMEM150C,ARC,SYN2,ALG1,ADGRL3,ATMIN,WSCD1,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,TNS2,HIF3A,ZNF34,TK2,CABIN1,TNS1,NPL,TPM2,ZNF346,SMUG1,TRIO,TRPS1,NUTM2A,PPIL6,RUSC1,TSC1,ZKSCAN5,EIF4ENIF1,SLC35A4,LINC00689,BCL2L13,MTCH1,CCDC136,RBFOX3,LAT2,WRN,XRCC4,ZNF32,ZNF45,PCBP1-AS1,FTSJ1,STOX2,CIAPIN1,SLC17A7,PDSS2,KAT6A,HNRNPA3,FAM219B,FAM198A" MicroRNA hsa-miR-30d:mirSVR_highEffct hsa-miR-30d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.20E-125 6.70E-122 1.02E-123 9.34E-123 316 1774 "RALGAPA1,CLK4,ABHD6,GALNT16,GALNT13,RNF157,ADD1,BRAP,KIAA1211,LRFN2,ADRB2,AP2A1,ZNF608,INTS2,KCTD16,HACE1,TAOK1,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,UPRT,VAT1L,USP37,PPP4R4,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B2,DPY19L3,ADGRB3,SEC11C,NRP2,BID,KSR1,DST,CALB2,CABP7,SLC25A14,CARS,CBS,USP2,SYNGR3,DGKI,SEPT7,ZBED1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,NDST3,NRXN3,FAM189A2,QKI,MAP4K4,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ZNF521,ZFP28,SLC35F1,CLOCK,GDA,OSBPL3,CSNK1G3,PDE4DIP,GREB1,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TBC1D5,MATR3,KCTD8,MAML1,YTHDC1,JAKMIP2,ALKBH8,PLPPR4,SACS,SPOCK3,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,RCAN1,MAMLD1,DNM1L,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,DCTN4,EPB41,EPB41L2,LRRC17,STX2,DENND4A,EXTL2,ABCA8,SH3YL1,SCML2,GORAB,AMOTL2,SCARA3,MEX3B,SYNCRIP,RGPD5,UFM1,FAM49B,ATP6V1H,KHDRBS3,NSG1,MSANTD4,OGA,ZMAT1,CHL1,TRAF3IP2,IP6K3,ERAP1,KIAA1841,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,TNRC6A,GNAO1,ADGRA3,PRUNE2,TDRKH,GRB10,GRIA2,CIT,FAM19A2,GUCY1B1,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,SMAP1,SOWAHA,ZNF678,FAM69A,LRRTM1,JAK2,STXBP5,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,CHIC1,MEIS2,MID1,PPM1L,ADAM22,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,PCDH9,PDE4D,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,TMEM260,PTPN13,USP47,OXR1,REV3L,PRRT2,ERI2,FIGN,SETD5,EXD2,CARF,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN8A,SUPT20H,FRMPD1,ARX,KIF16B,CPEB3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,FAM81A,KANSL3,PKNOX2,TET1,ZFP1,RCOR3,TTC17,LIMCH1,SNRPN,TMCC1,MYO16,BDP1,DOK5,KDM3A,SP4,HECW1,SPART,CLASP2,SSTR2,NKAIN2,STAU1,ZSCAN29,NEK4,RGL1,STXBP1,SYPL1,COBL,CAMTA1,MCF2L,ADGRL3,DMXL2,SATB2,USP22,CLASP1,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,SLC44A1,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,DCBLD1,ANKRD20A2,SSBP2,CCDC14,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,SLC30A4,MAP3K12,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,HNRNPA3,PHTF2,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-641:mirSVR_highEffct hsa-miR-641:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-125 8.96E-122 1.34E-123 1.23E-122 331 1950 "RALGAPA1,KCNH8,NCKAP5,ACTN1,KLHL32,BRAP,PLEKHH1,KIAA1211,MTUS1,HECW2,CC2D2A,TAOK1,ALCAM,ARHGAP20,AMPH,ZFAT,OGT,LRCH2,MAP4K3,PKP4,APBA2,VAT1L,USP37,TMEFF1,CADPS,LINC00173,ZBTB10,ATP2B2,RNF182,BACH1,ZNF599,DST,CA8,THSD7A,KALRN,PTBP2,CAMK2G,HIP1R,ISPD,CBS,CLDN10,LRBA,LRRFIP1,MAGI1,CDO1,CCPG1,SRSF11,SOCS6,CHN2,QKI,SRP14-AS1,MAP4K4,FAM149A,AKAP6,COL4A5,LETMD1,SLC4A8,ABI3BP,AHCTF1,NRG2,CNRIP1,CPS1,FAM171B,ANKRD44,NCOR1,OSBPL3,CSNK1G3,PHACTR3,CNTNAP2,SLITRK5,DZIP3,PHF14,USP6NL,CCDC144A,HDAC9,ARHGAP32,GAPVD1,ZFYVE16,SPOCK2,PITPNC1,SPATA2,YTHDC1,ZNF804A,MYEF2,ZC3H11A,PLPPR4,FAM107B,DMD,USP3,DMTF1,PDCD6IP,DTNA,ECM2,DNAJB6,DNM1L,GOLT1B,E2F5,E2F6,EBF1,EDN1,RASGRP1,SEMA3D,PHF20L1,EIF4G2,EIF5,RGS17,TMEM35A,EMX2,EPHB1,GPHN,DNAJC27,F8,FAM198B,TUBA1B,SCML2,GORAB,FGF13,FGFR1,PRKAG2,MEX3B,HPCAL4,NELFCD,TRMO,CELF1,STAU2,FYB1,GABRG2,KIAA1841,WASHC2A,PCDH17,BRD8,SPIN1,RAB30,MAP7D2,FUT10,CCDC184,STON1,SERP2,ATE1,FAM19A2,PSIP1,MAP4K5,ZHX1,PACSIN2,ARHGAP36,ELOVL5,ZDHHC15,DHX35,CELF5,SMAP1,FAM69A,SLC35G1,METTL21A,KCNB1,KCND2,KCNH2,KIF5A,KIT,LAMP2,LIG4,PAXBP1,SYTL4,NCOA7,SMAD9,MAP4,LYPLAL1,MAT2A,MBNL1,SRSF12,POC1B,AFDN,ZNF680,BLOC1S2,ADAM22,MXI1,NEFH,NEK1,NELL2,NF1,SLC11A2,NRCAM,NTRK3,PCDH8,PCDH9,PDE4B,PDPK1,GNG2,PIK3C2A,CCSER2,SNX10,PLCL1,TRHDE,MAPKAP1,STRN3,LRP12,EXOSC10,EPB41L4B,TATDN3,PPP2R5E,KANSL1,PKIA,MAPK4,MAPK10,GRAMD1C,PRPH,RELN,PIGG,CNTLN,PTK2,SPDL1,TMEM260,PTPRG,RIPOR1,CEP97,ZCWPW1,OXR1,RDX,RFX2,RFX3,RGS4,SLC25A36,RNASEL,ZFHX4,TMLHE,CARF,ROBO1,CCDC102B,ARMH4,BAALC,ATP8B4,GLDN,CLIP1,RTN1,ZNF331,RMI1,SATB1,SCN2B,FNIP1,SEC14L1,TRA2B,CPEB3,CHD9,FBXO11,FNDC3A,CNKSR2,NUBPL,ABLIM3,FAM81A,EPN2,KANSL3,KDM4D,SEPHS1,ARHGEF40,SLC14A1,ELMO2,SLC22A4,CXXC4,RCOR3,SNRPN,USP33,BDP1,ZC3H13,RBM26,SPART,LMO3,ATP10B,NKAIN2,ERBIN,ZSCAN29,ELOVL4,TTBK2,RGL1,DIP2A,ADHFE1,VPS13A,DNAJC9,PLCB1,SYN2,SYT1,CAMTA1,ADGRL3,ZEB1,SYNE1,PCDHB9,PCDHB3,SLC35G2,PCDHA1,TEK,ITGB3BP,AP4E1,ZNF106,ERCC6L2,PARD3,KAT6B,NPL,METTL3,SMUG1,RUNDC3B,STXBP4,TRPS1,ANKRD20A2,CLHC1,UBE3A,UCHL1,PLEKHH2,CLDND1,XRCC4,ZNF711,MICU3,ZNF32,KCNT2,EML6,SMARCAD1,INTS3,LINC02210,STOX2,PRDM10,FIP1L1,PDSS2,FAM13C,AMN1,UBE3B,KAT6A,SMIM8,HNRNPA3,PHTF2,SNX14,FRMD6,NETO1,AP3B2,LAS1L" MicroRNA hsa-miR-448:mirSVR_lowEffct hsa-miR-448:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-125 1.36E-121 2.00E-123 1.84E-122 323 1859 "VWA5B2,KCNH8,ACADM,NCKAP5,KDM5D,NDRG2,GALNT13,AXIN2,UNC5A,KIAA1211,RNF150,ADRB2,KLHL13,KCTD16,HACE1,OSBPL1A,OSBPL6,TAOK1,SMIM17,ARHGAP20,CARNS1,AMPH,ZFAT,ANK2,LCORL,MAP4K3,APBB2,APC,BCAS1,TMEFF1,SPTBN4,PCDHGB4,TMEM108,SLC4A4,ATP1B3,ATP2A2,RNF182,N4BP2L1,ATP6V1G2,DOCK11,ADAM23,BACH1,ADGRB3,ZNF599,BMPR1B,ARHGEF7,JAZF1,CACNA1I,CACNA1G,CACNB4,CABP7,ISPD,SPAG9,PRC1,LDB2,DCLK1,MAGI1,FOXN3,CHN2,CNOT8,CLCN3,C4orf33,QKI,FHL5,CNN3,ARHGEF6,CNTN1,AKAP7,IQCK,AKAP6,AKAP5,RCHY1,TBPL1,AHCTF1,CLOCK,HAPLN1,ANKRD44,RGS6,ARHGEF10,SIPA1L1,KIAA0040,PLCXD3,PNPLA8,GREB1,RIMS2,KIAA0408,KIAA0586,KCTD8,PABPC5,ARMCX4,SPATA2,JAKMIP2,DDX46,RHOBTB1,PLPPR4,SACS,DMD,USP3,DNAJB6,AASDH,EDN1,EDNRA,EDNRB,FEM1B,SEMA3D,FRY,PHF20L1,TENM1,C3orf18,EMX2,COQ7,IGSF6,EXTL2,DLC1,ZSCAN30,POLR1B,FGF12,SCARA3,IP6K2,SYNCRIP,FOXO3,ANKFY1,ATP2C1,ZNF605,KHDRBS3,CGREF1,STAU2,FYN,MEGF11,MEGF10,GABRG1,TRAF3IP2,GAD1,ERAP1,MTHFD2,KIAA1841,GCK,ALDH1L1,NFU1,FREM1,PPARGC1A,GLI2,ZNF638,GNG4,GPT2,ADGRA3,TDRKH,CNTRL,ATP2B1-AS1,BTN2A1,BVES,PSIP1,HAS2,DDX19B,TNFAIP8L3,BACH2,GABARAPL2,IGFBPL1,IRF8,C2orf72,NIM1K,NME9,SLC35G1,KCNJ16,IPO5,LAMP2,MAP2,MATN2,ADAM11,LRP1B,KCTD6,MIA2,KITLG,PPM1L,MMP16,MSR1,TAGLN3,MYCN,MYO5A,MYO9A,NEXMIF,NEFM,NF1,NFE2L2,ALDH1L2,SLC11A2,NTRK2,CLDN11,OXTR,PCDHGC3,PCSK5,TMOD2,PFKFB2,PFKFB3,SERPINI1,PIK3R1,SNX10,KCTD15,PLCL1,PURG,PMP22,LRP12,RETREG2,PPM1B,CCDC144B,PKIA,EPDR1,GRAMD1C,HYDIN,BCAS3,VPS13C,PTCH1,ANKHD1,MTMR10,TMEM260,FAM66C,SH3TC2,SUSD4,ENOX1,RFX3,SLC25A36,RIC8B,LGI2,SETD5,ROBO1,YY1AP1,ATP8B4,GLDN,TCP11L1,LRRK2,CLIP1,ZNF354C,RYR3,AP1AR,GALNT10,SUPT20H,KIF27,KIF21A,KIF16B,CPEB3,FBXO11,BTBD3,ARHGEF40,NAPB,GKAP1,LMBRD1,FAM126B,MYO16,KDM4B,USP33,SOX11,KDM3A,SP4,HECW1,MYCBP2,KDM4C,ZC3H13,SPART,TROVE2,ITPRID2,NKAIN2,ERBIN,ZSCAN29,ADHFE1,KANK1,NECAB1,SYNE2,C12orf76,TACR1,ANKRD12,TAL1,ADGRL3,FBXW11,TCF4,DMXL2,SATB2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SLC35G2,AP4E1,SLC44A1,FAM124A,RIMBP2,CSMD1,TRIO,TRO,TRPS1,PPIL6,TTTY15,CLIP2,PCDH20,ZIC2,ZNF24,ZNF28,ELFN1,ZFP41,MKRN3,LYPD6,SPHK2,REEP1,FSTL5,EML6,SMARCAD1,EVI5,TMEM178A,FIP1L1,PARP11,EPM2A,RTN4,HNRNPA3,ADAMTSL3,RNF170,NHSL1" MicroRNA hsa-miR-16-1*:mirSVR_highEffct hsa-miR-16-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-124 1.54E-120 2.23E-122 2.05E-121 313 1759 "RALGAPA1,ACADM,NCKAP5,GALNT16,CCDC85A,PWWP2A,RNF150,HFM1,SPARCL1,ALCAM,FAM135A,OGT,ANK2,MAP4K3,APAF1,UPRT,BCAS1,LGR5,CDC14B,CADPS,ZSCAN18,NUMB,ATP2A2,ALDH7A1,N4BP2L1,MPDZ,NAE1,MYRF,CH25H,CARS,RUNX1T1,KRIT1,USP6,LRBA,DCLK1,CFL2,COPB2,NPIPA1,CHN1,PLEKHB1,LHX2,FBXO7,QKI,FHL5,CNN3,CNR1,AKAP6,WHRN,COL9A3,ABI3BP,RCHY1,COX4I1,CPS1,FAM171B,C2CD2,AKAP12,TRIM69,CSNK1G3,PHF14,USP6NL,ARHGAP24,LIN54,MATR3,DAPK1,BRINP1,SPATA2,FBXL5,TMEM130,RHOBTB1,DLX1,USP3,DYNC1I1,CPEB2,SLC12A6,DPP6,DTNA,ECM2,DNM1L,GOLT1B,EBF1,EDIL3,SNX29,RASGRP1,SEMA3D,KLHL5,FRY,PHF20L1,SUGP2,MRO,MBNL2,GOLGA7,EIF4G2,IRAK4,C8orf37,ENPP6,GPHN,SRRM1,EZH1,NRN1,CLVS1,ABCA8,ZNF585B,ACSL4,ST3GAL6,GORAB,FHL1,SUCO,PCYOX1,ATP13A4,FLT1,ANKFY1,DCTN2,CAMKK2,STAU2,CHL1,TRAF3IP2,ERAP1,LRRC37A6P,GCNT2,ADAM28,GFRA2,PPARGC1A,MALT1,TCERG1,COPS8,ZNF638,CBX1,LUZP2,FERMT2,PCLO,CNTRL,ATP2B1-AS1,GRB10,COQ10A,AP4S1,PSIP1,MAP4K5,UBE2QL1,ZHX1,MIER3,HLF,ZDHHC15,LRRC75A,SMAP1,IL6ST,ZNF678,NME9,JAK2,KCND2,IPO5,STXBP5,KTN1,LAMP2,PAXBP1,SMAD1,MARK1,MARK3,MBP,MEIS1,MEIS2,SRSF12,MITF,XRRA1,ZNF680,ADAM22,NRBP2,NELL2,NF1,NFE2L2,ALDH1L2,NTRK2,LOC100128398,CLDN11,P2RY1,GPR137C,GLIPR1L2,PDCD2,PRTG,ENPP2,OLA1,PIK3C2A,PCDH18,PDZRN4,TATDN3,KANSL1,PKIA,MAPK9,VPS13C,ELOVL2,TMEM260,ZSCAN32,PTPRG,PTPRN2,C1orf109,PTX3,TTC13,USP47,FAT4,ZDHHC14,RET,FIGN,KLHL11,SLC25A36,PBRM1,RNASEL,CCDC82,SETD5,TMLHE,GSTCD,ELP2,SPIN3,LRRK2,CLIP1,CCDC112,TRAPPC13,SALL1,SEMA6D,ATXN7,TNFRSF19,SMPD3,SEC14L1,CASC3,RASA3,FERMT1,CPEB3,SHC4,FHOD3,ANKRD6,WDR37,DHX30,SEPHS1,SLC12A2,RCOR3,MBD5,KIF13A,USP33,DOK5,SP4,MYCBP2,SPART,ITPRID2,SSTR1,SS18,STAU1,ELOVL4,RGL1,ZC3H4,ANKRD28,ANKRD12,MTCL1,PJA1,CAMTA1,FBXW11,ZEB1,RPGRIP1L,TCF12,SZT2,PCDHB10,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,FAM200B,DICER1,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,FAM124A,TP53BP2,RGMB,TRIO,AMACR,TRO,TTC3,UGT8,WRN,CLDND1,RICTOR,GUSBP1,ZNF708,NDRG4,ZNF138,TMEM237,POLR3H,ZSCAN26,DPYSL5,ANKS1B,SPIRE1,ZNF225,EMSY,MFF,RNF103,ADAMTS9,KCNAB1,FAM47E,MPPE1,WNK3,PDSS2,AMN1,KAT6A,PHTF2,NLRP3,KLHDC1,FRMD6,IFT88,SENP7" MicroRNA hsa-miR-587:mirSVR_highEffct hsa-miR-587:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.20E-124 2.35E-120 3.35E-122 3.09E-121 316 1796 "ABHD6,XKR4,GALNT13,PTCHD1,OLMALINC,OSBPL1A,CC2D2A,C1QTNF3,FAM135A,ANK2,MAP4K3,PKP4,DDO,USP37,CADPS,LINC00173,SLC4A4,ATP6V0A1,BBS2,NRP2,DST,SCAPER,CA4,CACNA2D1,THSD7A,CALM1,KALRN,PTBP2,VXN,CAST,SPAG9,RUNX1T1,SCARB1,LRBA,ZMYM4,MAGI1,CDR1,CLGN,DIS3L,CHN2,MS4A7,CNOT8,SLIT2,RAB28,PPT2,QKI,CNGA3,ARHGEF6,ARMC8,ANKRD35,AHCTF1,SMARCAL1,SLC35F1,RBM39,RNF14,GDA,CSF1R,ARHGEF10,CSNK1G3,SUSD5,ERC2,UBXN2A,PNPLA8,ZSCAN23,DOCK4,KATNAL2,GAPVD1,TCAF1,RIPOR2,KIAA0586,MAML1,TMEM170A,HEPH,MYEF2,MFAP3L,ZC3H11A,DDX46,ALKBH8,SPOCK3,RAB39B,DMD,CPEB2,PDCD6IP,DTNA,GOLT1B,E2F6,EDN1,SEMA3D,KLHL5,FSD1L,FAM13A,PHF20L1,EGR3,RASA4,AASS,GOLGA7,PLEKHA1,CALCRL,RABEPK,ETV1,SCML2,DLC1,CEP78,FDFT1,FER,FGF12,FGF14,FGFR3,POLK,SUCO,PSD2,PDLIM5,ATP6V1H,MPP6,FYB1,MEGF10,GABRG2,GAD1,RAPGEF6,IP6K3,LRRC37A6P,KIAA1841,SULT1C4,ADAM28,GFRA2,PCDH17,PPARGC1A,MALT1,TXNL4A,COPS8,DBF4,RAB30,TNRC6A,ZNF638,ZNF782,ADGRA3,TDRKH,STMN2,GRIA2,FAM19A2,PSIP1,FAM107A,IRAK3,NCKAP1L,ELOVL5,HNMT,SMAP1,ICA1,IDH3A,NKD1,SCIN,FAM69A,KCND2,KCNN2,KPNA5,LIG4,HECTD2,MAN2A2,AQP11,MBNL1,MEIS1,SRSF12,AFDN,ADAM22,MSR1,ZNF92,ZNF862,MYT1,NACA,CNOT4,NPR2,SMIM11A,GPR137C,CNTN3,PCDH9,ENPP2,GNG2,NALCN,RETREG1,GPSM2,FAM216A,PCDH18,TRHDE,MINDY2,PPM1B,TATDN3,PPP3CC,KANSL1,CEP41,PKIA,GRAMD1C,PRPSAP2,QRICH1,PTCH1,MTMR10,TMEM260,TTC13,TMEM231,MARCH1,CEP97,SH3TC2,KHDRBS2,RDX,ZMAT4,RET,ZFHX4,CCDC82,ZNF532,CARF,GSTCD,ROBO1,ELP2,CCDC102B,EPHA10,FBXW7,GLDN,ADAL,TCP11L1,LRRK2,ABCA11P,HUNK,KCNIP1,ZNF568,SALL1,SATB1,ATXN7,SCP2,FNIP1,TNFRSF19,GALNT10,SUPT20H,TRA2B,SCAF8,KIF21A,MYO18A,FBXO11,FHOD3,NLGN1,SLC6A11,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,SLC12A2,ZNF334,SLC14A1,BTBD7,ATF7IP,ZFP1,MBD5,SNRPN,PDZRN3,USP33,TRERF1,BDP1,DOK5,NMNAT2,SPP1,CDK19,LMO3,ATP10B,CLASP2,POGZ,NKAIN2,ERBIN,NXT2,RGL1,KLHL7,SYNE2,CAMTA1,DNMBP,ADGRL3,TBCEL,SATB2,TPCN2,CLASP1,PCDHB3,FRYL,FAM200B,DICER1,C18orf54,ITGB3BP,SLC44A1,NR2E1,FAM124A,KAT6B,TPM1,C9orf85,METTL3,PPIL6,UBE3A,USP1,TBC1D15,WIPF1,P2RY12,ZNF781,ZNF23,ZNF28,ZNF32,ZNF138,ZNF184,EMSY,EVI5,PRDM10,RNF103,HPS4,MPPE1,PARP11,FAM13C,FBXO36,CASC15,JMJD1C,RNF170,KLHDC1,NETO2,SENP7" MicroRNA hsa-miR-139-5p:mirSVR_lowEffct hsa-miR-139-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.52E-123 1.41E-119 1.98E-121 1.83E-120 319 1842 "SYN3,NDRG3,CCDC85A,GALNT13,ZNF608,MTUS1,PCDH19,SPARCL1,BBOX1,UNC79,SYT13,AMPD3,ZFAT,DPP10,CCDC146,LCORL,APBB2,APC,LGR5,TMEFF1,RASL11B,SLC4A4,ATP1B3,ATP2B2,AZGP1,MPDZ,BCHE,NRP2,DST,NAE1,MTMR2,IL33,CACNB4,CABP7,KALRN,CH25H,PRC1,CERS5,USP6,CBFA2T2,CDH2,NOG,CACNA2D2,SRSF11,CHN1,CHN2,NDST3,RAB28,FAM19A5,MAP4K4,CNN3,FAM149A,AKAP6,SLC4A8,ABI3BP,ENTPD4,RBM39,SNCAIP,SEC24C,ARHGEF10,IPCEF1,PDE4DIP,PHACTR3,SLITRK5,DZIP3,PHF14,CTH,GREB1,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP32,ZNF337,KIAA0586,MAML1,IP6K1,PABPC5,BRINP1,ZNF804A,MYEF2,TIAM2,MFAP3L,ZC3H11A,SNAP91,DLX1,RAB39B,DPP6,RCAN1,EDNRB,FRY,PHF20L1,APH1A,GOLGA7,CALCRL,EMX2,ABCA8,ST3GAL6,ZSCAN30,ZNF589,MED12L,OLFM1,PRKAG2,FHL1,MEX3B,PCYOX1,RGPD5,SLC37A3,DCTN2,TMEM107,ZBED3,HVCN1,UFM1,CAMKK2,ATP6V1H,KHDRBS3,CELF1,SARAF,MEGF10,GABRA3,RAPGEF6,ARFIP1,PPARGC1A,LYVE1,COPS8,SPIN1,RAB30,TOX3,GNAL,GNAO1,FERMT2,GPD2,STON1,GRIA2,DIDO1,PRDM5,CIT,ZBTB49,AP4S1,PSIP1,ADAMTS6,HSF2,SHISA6,KIAA1755,IL12A,INSM1,NME9,JAK2,KIF2A,KIT,STXBP5,KTN1,STMN1,LIFR,SMAD1,PIK3AP1,MBNL1,MEIS1,SRSF12,KCTD6,MIA2,PPM1L,MYCN,BEX5,NF1,NFE2L2,NOVA1,CHAMP1,CNTN3,PCSK5,PFKFB2,NALCN,ZNF655,SNX10,ZFYVE21,PKM,GPSM2,PCDH18,MTRF1L,PURG,STRN3,ING3,RETREG2,SEPT4,MINDY2,LRRN3,PPP2R5E,PRKACB,MAPK10,HYDIN,DIRAS2,GDPD1,RELN,BCAS3,PIGG,PTK2,PTN,ZIK1,PTPN13,PTPRB,PTPRO,PTX3,ZNF844,USP47,SH3TC2,FAT4,RAP1GDS1,RBBP6,KHDRBS2,RET,REV3L,PRRT2,ERI2,UBR7,SLC25A36,ZFHX4,C12orf49,CARF,ROBO2,RORB,NEK11,RPL15,MCMBP,GLDN,PTGR2,RTN1,TRAPPC13,SALL1,SEMA6D,SATB1,ATXN7,SEC14L1,GALNT10,SGK1,SH3GL3,KIF16B,CHD9,FBXO11,FNDC3A,CNKSR2,BTBD3,EPN2,DHX30,CPEB4,SMARCA4,RCOR3,SNRPN,TMCC1,MYO16,PDZD2,BDP1,FNBP1,KDM3A,MYCBP2,SPP1,TEX2,CDK19,LMO3,CLASP2,CAMTA2,SS18,SEPT8,ADHFE1,SULF2,SEPT3,STXBP1,NECAB1,SYNE2,C12orf76,TACC1,MTCL1,MCF2L,AGTPBP1,TBCEL,TBL1X,MGRN1,TCF4,TPCN2,CLASP1,PHF24,SLC19A3,VWCE,PMS2CL,ZFPM2,ITGB3BP,SLC44A1,KAT6B,TNS1,SYNPO2,STXBP4,CA14,SSBP2,SGK3,TUBB1,BCL2L13,VLDLR,KLC2,XPO1,PCDH20,ZIC1,ZNF24,ZBTB38,REEP1,TMEM198,DPYSL5,EMSY,CADM2,EVI5,PRDM10,CIAPIN1,FIP1L1,WNK3,FAM13C,ST7,PHTF2,FBXO36,FRMD6,NETO2,JPH3" MicroRNA hsa-miR-141:mirSVR_highEffct hsa-miR-141:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.11E-123 1.74E-119 2.42E-121 2.23E-120 300 1627 "ABCF1,SYN3,NCKAP5,ADD1,ADD2,PLEKHH1,BEND6,RTL9,SMIM17,PCDH10,AMPD2,UPRT,LGR5,TMEFF1,ARNTL,CDK13,STK33,STX16,ATP2A2,ADAM23,BACH1,NRP2,GPR146,ZNF599,ST3GAL5,MTMR2,JAZF1,GPC2,WASF1,THSD7A,KALRN,PTBP2,CAST,CCNH,USP6,SEPT7,CDC25B,L3MBTL4,TIGD7,DIS3L,CFL2,CHN2,PPT2,QKI,HECTD1,CNR1,COX4I1,AHCTF1,MYRIP,SLC35F1,CPS1,SEC31B,PREPL,CRMP1,RNF14,TRIM69,MROH8,ARHGEF10,CSNK1E,CSNK1G3,VCAN,PDE4DIP,PLXNA4,ERC2,APPL1,PHF14,ZSCAN23,DCAF4,KIAA0408,DOCK4,HDAC9,KIAA0586,DAPK1,DBI,ARMCX2,TMEM130,LYPD1,RHOBTB1,SNAP91,SV2B,SPOCK3,GRIN3A,DYNC1I1,CPEB2,ABCC5,HIPK3,YAF2,EGFR,KMT5B,GOLGA7,KCTD3,TMEM35A,PAN3,EPHB1,STX2,IGSF6,ANKMY1,EYA1,DLC1,ST3GAL6,FER,OLFM1,POLR1B,FGF13,SUCO,RGPD5,FLT1,NELFCD,SMC2,UFM1,TPK1,KHDRBS3,CELF1,STAU2,MSANTD4,MEGF11,MEGF10,ZNF234,C15orf41,GCNT2,PPARGC1A,TCERG1,GLI2,ZNF638,CBX1,KDM2B,LOXL3,GPD1,GPD2,GPR12,PCLO,GRB10,GRIA2,ADAMTS13,GRIN2D,ATE1,GSN,GSTT2,GUCY1B1,MIER3,HLF,ACOT7,HNMT,EID2B,RBPJ,FAM69A,INSM1,KIT,IPO5,STXBP5,LAMP2,MAP6,MARK1,AQP11,MBNL1,MEIS2,PPM1L,AFDN,COL28A1,RTL5,NFE2L2,DNHD1,SLC11A2,NRCAM,OGG1,P2RY1,GPR137C,PCDH8,PCDH9,PCSK5,PDCD2,NALCN,ZNF655,PLCL1,SMIM7,PNMA3,TRHDE,SCHIP1,ING3,PPM1B,PPP2R5E,PRKACB,MAPK9,GDPD1,CNTLN,PTCH1,MTMR10,SPDL1,TMEM260,PTPRD,PTPRE,PTPRG,SH3TC2,FAT4,KHDRBS2,MSANTD2,ZMAT4,REV3L,SETD5,NEK11,ADAL,TCP11L1,STK32B,LRRK2,ATAT1,CLIP1,NCBP3,FAM192A,SATB1,ATXN7,SCP2,FNIP1,CASC3,SUPT20H,COPZ1,HSPA4L,CHD9,R3HDM2,SEC31A,FAM81A,SEPHS1,CCDC88A,SLC14A1,ATF7IP,TET1,CPEB4,RCOR3,ANKRD36,LIMCH1,MBD5,LMBRD1,SNRPN,RBM34,PDZD2,KDM3A,SP4,MCF2L2,RBM26,LMO3,ATP10B,CLASP2,POGZ,ITPRID2,ZNF302,NKAIN2,ZSCAN29,TTBK2,KANK1,SULF2,STXBP1,KLHL7,SYNE2,PLCB1,MTCL1,FAM208A,ADGRL3,TBCEL,FBXW11,TCF4,SIN3B,ZEB1,TCF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,TIAM1,ERCC6L2,KAT6B,METTL3,TSC1,RPL7L1,UBE3A,WIPF1,LAT2,CLDND1,RICTOR,ZNF711,ZNF17,ZNF19,MICU3,KCNT2,ANKS1B,EMSY,MFF,FAM13C,MRPL47,RTN4,HNRNPA3,PHTF2,NLRP3,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-2113:mirSVR_lowEffct hsa-miR-2113:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.67E-123 2.61E-119 3.58E-121 3.29E-120 322 1881 "KCNH8,ABHD6,EMILIN3,CCDC85A,TMCC3,DPY19L2P4,SLC24A4,ZNF608,MTUS1,OSBPL1A,KIAA1324,OSBPL6,USP35,ALCAM,CDC42BPA,ANK2,FGD2,SMIM29,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PHYHD1,TNRC6C,PPFIA3,CDK10,PPP4R4,TMEFF1,SPTBN4,CDK13,N4BP2L1,DOCK11,ADAM15,BACH1,BCHE,BMPR1B,ST3GAL5,FUBP1,BTK,LDLRAD4,CA8,KALRN,PTBP2,PRC1,KRIT1,CERS5,DGKI,ZMYM4,L3MBTL4,LOC730101,ZNF445,CLGN,RCBTB2,TAOK2,NDST3,RAB28,ABCG2,TOGARAM2,CREM,SH2B1,NCOR1,CSF1R,RGS6,LRIG1,SIPA1L1,PDE4DIP,KIAA0040,ARHGAP32,ARHGAP24,EARS2,RASSF2,LONRF1,MATR3,KCTD8,DGKG,DAPK1,TIAM2,KIAA0319,ZC3H11A,POM121,RHOBTB1,SACS,SPOCK3,WDR20,GRIN3A,RAB39B,USP3,DOCK2,DMTF1,ARRDC4,DTNA,E2F5,E2F6,EDNRA,EDNRB,HIPK3,FCF1,KLHL5,FRY,PHF20L1,TMEM132E,RASA4,GOLGA7,ELN,C8orf37,EPHB1,SRRM1,ERBB4,SPEG,TLR7,RRAGB,EZH1,CLVS1,ACSL4,CORO2B,SEC24B,MED12L,FGFR1,PRKAG2,FHL1,FLT1,PSD2,SPECC1,FAM49B,CAMKK2,ATP2C1,ERGIC3,ST6GALNAC3,DOT1L,ABLIM2,CHL1,B4GALNT1,C15orf41,SRRM4,TUBGCP4,CYP46A1,ZNF276,STARD3,CBX1,KDM2B,GNAO1,ADGRA3,FUT10,STON1,LPAR4,GPR37,GRIA2,DIDO1,GRM8,AP4S1,SOX21,GUCY1A1,FAM222A,UBE2QL1,TOX2,PADI2,MIER3,AGBL5,ZDHHC15,SHISA6,CELF5,ICA1,MSL1,IDH3B,IL6ST,SLC6A17,NME9,STMN1,LIG4,MAP6,MARK1,MAT2A,MBD1,MBNL1,SRSF12,SCAMP5,AFDN,MMP16,ADAM22,MSR1,NRBP2,MYO5A,NEXMIF,MYT1,NELL2,NF1,NOVA1,NPR2,SLC11A2,NTRK2,LOC100128398,GPR137C,CNTN3,PCDH9,CDK18,PDCD2,PDE1C,PDE3A,PDE4B,GPR85,OLA1,FAM218A,FAM216A,ANKRD16,LRP12,SCHIP1,SEPT4,MBOAT7,MINDY2,PPP2R2C,RANBP3L,MASP1,APTX,SNRK,ELOVL2,PTN,PTPRB,PTPRE,ZNF793,SH3TC2,REV3L,FIGN,PBRM1,RNASEL,KLHDC8A,CYB561D1,ROBO1,CCDC102B,SNX22,NEK11,RPL15,SPIN3,ZC3H14,RPS6KA2,ABCA11P,KCNIP3,CLIP1,RTN1,ZNF331,MAPK12,ATXN2,LRFN5,SUPT20H,SCAF8,FAM102A,SH3GL3,FUZ,FHOD3,ST6GAL1,FAM81A,KANSL3,KBTBD4,BTBD7,GKAP1,RCOR3,ANKRD36,MBD5,PDZRN3,SOX11,ZSWIM8,TEX2,UNC5B,PEG10,PBLD,CLASP2,ELOVL4,NEK4,SEPT8,KANK1,VPS13A,ADAMTS17,MTCL1,SATB2,PCDHGA11,SYNE1,FAM189A1,OBSL1,PUM2,ZFPM2,AP4E1,TIAM1,MTMR14,ASXL3,ERCC6L2,PIK3R5,TPM1,ZNF346,PDSS1,PPIL6,DCBLD1,TSC1,SSBP2,CLHC1,FAM155A,UBE2H,UBE3A,PLEKHH2,USP1,VLDLR,SLC47A2,ZIC2,MICU3,NDRG4,MKRN3,CELF4,TMEM237,EML6,CADM2,SLC38A1,PRDM8,TMEM178A,CIAPIN1,MDH1B,FIP1L1,WNK2,FAM13C,AMN1,FZD3,SMIM8,PHTF2,NHSL1,SNX14,FRMD6,SPATA13" MicroRNA hsa-miR-411*:mirSVR_lowEffct hsa-miR-411*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-123 2.80E-119 3.78E-121 3.48E-120 332 2000 "ACADM,NDRG3,FMNL2,ADD1,ESYT2,DPY19L2P4,OSBPL1A,WDR35,OSBPL8,PCDH10,BBOX1,UNC79,ZFAT,DPP10,C6orf89,APC,MAGEE2,UPRT,VAT1L,LGR5,PPP4R4,RGS20,ASPA,N4BP2L1,ATP6V0A1,DOCK11,ADAM23,TTLL9,MIR9-3HG,KSR1,BMPR1B,DST,SCAPER,MTMR2,PTBP2,CAST,CH25H,ISPD,CCNH,CLGN,MS4A7,CNOT8,EPS15L1,NRXN3,FAM19A5,QKI,MAP4K4,CNN3,IQCK,AKAP6,SLC4A8,TBPL1,ZFP28,PREPL,C2CD2,CREM,HAPLN1,NCOR1,GDA,MROH8,CSF2RA,OSBPL3,VCAN,SOCS5,VAC14-AS1,CNTNAP2,DZIP3,PLCXD3,PNPLA8,KIAA0408,DOCK4,RIPOR2,ARHGAP24,LONRF1,MATR3,KIAA0586,KCTD8,DGKB,SCRN1,DBI,GIT2,ARMCX4,ZBTB24,HEPH,MYEF2,TIAM2,MFAP3L,FBXL5,DDX46,PLPPR4,WDR20,DOCK2,SLC12A6,ACOT8,MAMLD1,DNM1L,GOLT1B,E2F6,EDIL3,KLHL5,FRY,OPTN,PHF20L1,SUGP2,KCTD3,IRAK4,PCOLCE2,VPS13B,EPB41L2,LRRC17,RABEPK,ERBB4,CDKL3,VPS26C,DNAJC27,EXTL2,EYA1,CLVS1,ABCA8,ZNF461,ACSL4,GORAB,SLC9B2,FGF12,FGFR1,FGFR3,MEX3B,HPCAL4,ANKFY1,UFM1,TPK1,ZNF605,ST6GALNAC3,STAU2,SDCBP2,MEGF10,C15orf41,DISC1,SEPT9,LRRC37A6P,KIAA1841,IGSF5,GCNT2,TUBGCP4,SULT1C4,MSTN,ADAM28,MMADHC,LYVE1,TCERG1,MSL3,MAP7D2,GPT2,WDFY3-AS2,FUT10,PCLO,GRIA2,ADAMTS13,GRM8,BTN2A1,GSTM5,ELOVL5,ZDHHC15,HSF2,ZNF546,ZIC5,LRRCC1,IL12A,FAM69A,INPP5B,ITPKB,JAK2,SLC35G1,KCND2,KCNN3,KIF5A,KIT,STXBP5,KTN1,LAMP2,LIG4,MAP2,MARK1,AQP11,MATN3,MBP,KITLG,MMP16,NEXMIF,NF1,NFE2L2,NOVA1,NTRK2,NUCB2,CHAMP1,P2RX7,PALM,PCDH8,PDE4D,GPR85,ZNF655,XRN1,FAM216A,PLCL1,PURG,MAPKAP1,ING3,POLR2F,PPM1B,RANBP3L,VSTM2L,PRKACB,GRAMD1C,DIRAS2,VPS13C,PTCH1,ANKHD1,ELOVL2,PTN,STK32A,PTPRG,ZNF615,RAD17,ZNF493,RBBP6,MSANTD2,RET,ERI2,MORC4,UBR7,RGS4,SLC25A36,DCUN1D2,ROBO1,PCMTD2,CCDC102B,RPE,NEK11,FBXW7,BAALC,ZC3H14,MCMBP,STK32B,PTGR2,ZNF331,LRFN5,SCN8A,PEAR1,KIF16B,CPEB3,CHD9,FNDC3A,FHOD3,SEC31A,DZIP1,WDR37,SLA,PPP4R3A,BTBD3,KANSL3,CCDC88A,GKAP1,IFT122,ANKRD36,LIMCH1,SNAP25,MBD5,PDZRN3,MYO16,DOP1A,BDP1,FNBP1,GLT8D1,UHRF1BP1L,ERC1,ZNF423,ZC3H13,ZNF621,ZNF302,CEP68,KANK1,JMJD6,ADAMTS17,C12orf76,PJA1,DNMBP,SATB2,ZFP90,TRIM2,TCF12,CLASP1,PUM2,ARHGAP9,CRTC1,DICER1,ITGB3BP,AP4E1,MTMR14,TLR4,LRRC8A,KAT6B,SYNPO2,STXBP4,TRPS1,PPIL6,SSBP2,TTTY15,TUBB1,FAM155A,USP1,VAV1,CCDC14,WIPF1,CLDND1,XPO1,XRCC4,MKRN3,SMARCAD1,SLC30A4,EMSY,EVI5,VPS35L,MDH1B,MPPE1,RGS7BP,SMIM8,HNRNPA3,FBXO36,KLHDC1,FRMD6,CPNE4,SENP7" MicroRNA hsa-miR-802:mirSVR_lowEffct hsa-miR-802:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-122 1.17E-118 1.55E-120 1.43E-119 315 1809 "ACADM,ADD1,BRAP,PLEKHH1,ZNF608,HECW2,RTL9,OSBPL1A,WDR35,AK2,SEMA6A,PITPNM2,OGT,CDC42BPA,FGD2,LCORL,MAP4K3,APBB2,USP37,PPP4R4,MARK4,SLC4A4,STX16,ADAM23,ZNF599,SYNJ1,ARHGEF7,IL33,CFAP410,CACNB4,CALB1,CALM1,CAMK2G,CAST,SPAG9,CLDN10,CDH2,LRRFIP1,DLGAP1,CCPG1,PLAA,ABCG2,QKI,COL4A5,COL9A1,LETMD1,AKAP5,ABI3BP,TBPL1,TOGARAM2,SLC35F1,PREPL,RBM39,CRHBP,HAPLN1,TRIM69,MROH8,SNCAIP,OSBPL3,SOCS5,CNTNAP2,CST3,DZIP3,GREB1,ARHGAP32,ARHGAP24,DCAF8,TBC1D5,KIAA0586,IST1,PITPNC1,ARMCX2,MYEF2,KLHL3,ZC3H11A,GSDME,SPOCK3,FAM107B,KIF19,DLX1,GRIN3A,USP3,NR1D2,DOCK2,SLC12A6,DTNA,DUSP9,MAMLD1,EDNRB,TMTC1,FAM13A,SUGP2,EGFR,MRO,EIF4G2,C8orf37,VPS13B,LRRC17,GPHN,STX2,DENND4A,NCALD,ZNF549,ETV1,ANKMY1,NRN1,FCGR1A,FKTN,FECH,SEC24B,SLC9B2,FER,FGF12,FGFR1,FGFR3,POLK,SYNCRIP,RGPD5,FOXO3,FLT1,SLC37A3,ATP2C1,KHDRBS3,NSG1,GABRA3,GABRB3,GABRG1,IP6K3,CPLX2,GATM,IGSF5,CYP46A1,COPS8,SPIN1,MSL3,GLUL,KDM2B,HTATSF1,KCNMB4,FERMT2,GPD1,GPR12,STON1,GPR37,PCLO,RABL2A,ZHX1,FRMD5,AGBL5,HNF4G,NEGR1,DHX35,HSF2,IL6R,INSM1,ITPKB,KCND2,LAMP2,LIFR,PIK3AP1,ZNF667-AS1,MAT2A,MBNL1,MBP,MEIS2,MIA2,KITLG,MID1,MITF,AFF1,MMP16,SAMD5,MSI1,ADAM22,HS6ST3,MYO5A,NEXMIF,MYT1,NCAM2,ZC3H12B,CCDC13,NELL2,NF1,NOVA1,NTRK2,IGSF11,DPY19L2P2,PCDH8,PCSK5,PFKFB2,OLA1,SERPINI1,CCSER2,XRN1,SMIM7,PNMA3,PDZRN4,LRP12,RETREG2,EPB41L4B,MAPK7,BCAS3,TMEM260,PTPRB,PTPRD,C1orf109,TTC13,QDPR,USP47,SH3TC2,ZDHHC14,GTDC1,ZNF532,ROBO1,RORB,EPHA10,FBXW7,ZC3H14,ATP8B4,RXRA,STX1B,DGLUCY,ATXN2,SCP2,FNIP1,TNFRSF19,PEAR1,SUPT20H,SH3GL3,PPM1E,ARX,FERMT1,KIF16B,CHD9,CNKSR2,DZIP1,PPP4R3A,BTBD3,SEPHS1,ARHGEF40,LIMCH1,MYO16,DOP1A,ZHX3,ZSWIM8,NMNAT2,UHRF1BP1L,SPP1,KDM4C,ARHGAP26,CDK19,MCF2L2,PBLD,ITPRID2,SSTR1,LARP4,STAU1,CEP68,KANK1,SULF2,NECAB1,SYN2,COBL,ANKRD28,TACC1,KLHL4,ATMIN,TCF12,PHF24,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,C18orf54,ZNF106,TIMP4,TLR4,TMPO,RIMBP2,RGMB,SYNPO2,RUNDC3B,TTTY15,CLHC1,UBE2H,LINC00689,FLRT2,PLEKHH2,WIPF1,GUSBP1,ZIC1,TRIM9,ZNF45,MKRN3,ZNF195,ZFAND5,DHX33,PRTFDC1,SLC38A1,EVI5,GAL3ST3,NAV3,FIP1L1,KAT6A,ADAMTSL3,MSRB3,NHSL1,FXR1,FRMD6,ST8SIA2" MicroRNA hsa-miR-452:mirSVR_highEffct hsa-miR-452:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-122 1.18E-118 1.55E-120 1.43E-119 309 1740 "RALGAPA1,KCNH8,ACADM,CLK4,BRAP,BEND6,AP2A2,TAOK1,SEMA6A,MARCH4,FAM135A,SYT13,ZNF687,ZFAT,OGT,ANK2,SHROOM2,CASK,MARCH3,ZBTB10,ATP1B3,MYOM1,DOCK11,BACH1,ADGRB3,BBS2,KSR1,SYNJ1,FUBP1,JAZF1,CA8,CAMK2G,CAST,SPAG9,CLDN10,KRIT1,SLC16A4,CDH2,TIGD7,CHN1,NDST3,EPS15L1,FAM19A5,C4orf33,QKI,MAP4K4,ARHGEF6,CNTN1,AKAP5,ABI3BP,RTTN,CLOCK,ARHGEF10,SIPA1L1,PLXNA4,FAM169A,ERC2,DOCK4,HDAC9,MATR3,DGKB,GIT2,YTHDC1,MYEF2,GSDME,GUCD1,RHOBTB1,SPOCK3,ZNF582-AS1,CHRDL1,DLX1,GRIN3A,DMD,CPEB2,DMTF1,CASP8AP2,DPYSL2,DTNA,ECM2,FAM78B,DUSP9,GOLT1B,EDNRA,ANKRD46,HIPK3,RASGRP1,KLHL5,TMTC1,FRY,YAF2,PHF20L1,EGFR,KMT5B,TENM1,CALCRL,PAN3,SRRM1,ADGRV1,FAM198B,CEP78,ZSCAN30,FER,FGFR3,AMOTL2,SYNCRIP,JKAMP,SPECC1,ATP6V1H,ERGIC3,AP4B1,SDCBP2,ZMAT1,GABRG2,IP6K3,TMEM8B,DISC1,KIAA1841,MSTN,NFU1,PPARGC1A,TXNL4A,CRCP,COPS8,GPR75,TOX3,TDRKH,CNTRL,GRB10,PSIP1,MAP4K5,HAS2,FRMD3,ELOVL5,HNMT,IGFBPL1,C9orf129,DHX35,IRF8,SOWAHA,RBPJ,DISP2,SCIN,IL6ST,FAM69A,IPO5,LAMP2,LIG4,LIMS1,PAXBP1,HECTD2,NCOA7,MAP6,MATN3,MBNL1,TM6SF1,LRP1B,MEF2C,ADAM22,SFR1,NF1,NPTX1,NRCAM,NUCB2,GLIPR1L2,CNTN3,DPY19L2P2,ETFRF1,PCSK1,PDCD2,SERPINI1,FAM218A,CCSER2,RETREG1,KCTD15,STRN3,SCHIP1,POU6F1,PPM1B,TATDN3,CEP41,MAPK9,RELN,CNNM2,SAMD9,APTX,SNRK,ANKHD1,MTMR10,PTPRG,PTX3,PEX2,PPP2R3C,PID1,CEP97,TMEM255A,FAM66C,RASGRF2,RADX,REV3L,ERI2,PBRM1,RNASEL,ZNF532,CARF,ROBO2,MRAP2,FBXW7,SPIN3,KIAA0895L,MCMBP,ATP8B4,LRRK2,KCNIP1,ZNF354C,SCP2,TRA2B,FBXO11,FNDC3A,PREX2,KANSL3,PKNOX2,SLC8A1,ARHGEF40,CCDC88A,BTBD7,SLC22A4,CPEB4,ZFP1,SMARCA4,RCOR3,ANKRD36,LIMCH1,MBD5,TMCC1,PDZRN3,BDP1,SOX15,SP4,ZC3H13,SPART,ATP10B,POGZ,NKAIN2,SS18,ERBIN,NXT2,NEK4,SEPT8,KANK1,NSFL1C,NECAB1,SYNE2,ARHGEF9,VPS13A,SYPL1,MTCL1,PJA1,TBCEL,KLHL4,TCEA1,SATB2,CUX2,ZEB1,DOCK9,GPRIN3,FRYL,FAM200B,ITGB3BP,SLC44A1,ERCC6L2,RIMBP2,TP53BP2,TPM1,C9orf85,RGMB,UBE3A,GORASP1,FLRT2,USP1,WIPF1,WRN,XRCC4,LGI4,ZNF19,ZNF23,MICU3,AGMO,MKRN3,LYPD6,TCEAL7,ZNF142,EML6,ANKS1B,TFIP11,UPF3A,SLC30A4,EMSY,CADM2,NAV3,PPP1R3F,FIP1L1,FAM13C,KAT6A,HNRNPA3,PHTF2,ACTR3B,KLHDC1,IFT88,NETO1" MicroRNA hsa-miR-19b:mirSVR_highEffct hsa-miR-19b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.97E-122 1.66E-118 2.16E-120 1.98E-119 288 1508 "ABR,ABHD6,NCKAP5,ACTN1,KIAA1211,DPY19L2P4,HECW2,WDR35,SRPX,PCDH10,FAM135A,CDC42BPA,LRCH2,MAP4K3,PHF12,APAF1,APBA2,USP37,LINC00173,CDK13,STK33,ZBTB10,CCAR2,STX16,ZNF583,ATP6V0A1,BARD1,NRP2,ST3GAL5,JAZF1,C5,IL33,CA4,THSD7A,CALM1,KALRN,CAST,RUNX1T1,PRC1,USP6,CBFA2T2,SEPT7,ZMYM4,LRRFIP1,EVI5L,TIGD7,CCPG1,CFL2,SRSF11,PLAA,CLTC,QKI,CNGA3,FHL5,CNTFR,AKAP7,ARMC8,FAM149A,LETMD1,COX4I1,SMARCAL1,ZNF521,IGDCC3,SLC35F1,CLOCK,GDA,CS,SNCAIP,CSF1,LRIG1,SOCS5,PDE4DIP,ERC2,APPL1,PHF14,PPP6R2,DCAF8,LONRF1,DAPK1,IP6K1,GIT2,DBN1,PITPNC1,ZNF804A,DDX46,RHOBTB1,SACS,WDR20,DLX1,USP3,CPEB2,ARRDC4,DTNA,ECM2,AASDH,EBF1,EDIL3,EDNRB,HIPK3,YAF2,FAM13A,EGR3,PLXNC1,EIF4G2,CERCAM,EMX2,ENPP6,NCALD,ABCA8,ACSL4,CORO2B,FER,MED12L,OLFM1,FGF13,SUCO,FOXF2,SYNCRIP,FLNC,FLT1,NBEA,ATP2C1,NSG1,FYB1,GABBR1,SIGLEC8,ARFIP1,ADAM28,MALT1,CRCP,CBX1,FERMT2,PRUNE2,GPR34,GRB10,KAT7,ELOVL5,ZIC5,ZNF678,FAM69A,KCND2,CREG2,MATN2,MATN3,MBNL1,MID1,ZNF680,BLOC1S2,N6AMT1,MYCN,MYO9A,ZNF862,IDNK,NME4,CNOT4,TBC1D25,OCRL,OXTR,PCSK5,PDE1C,PDE4D,SLC10A4,CCSER2,PLCL1,JAKMIP1,MAPKAP1,STRN3,LRP12,SCHIP1,SH3KBP1,POLR2F,MINDY2,PPM1B,PPP2R5E,PRKACB,RELN,PSD,MTMR10,TMEM260,PTPRD,CASTOR1,PTPRG,ACSM5,RAD51D,RASGRF2,RBBP8,RET,GTDC1,SLC25A36,SETD5,GSTCD,ROBO2,STK32B,LRRK2,ABCA11P,CLIP1,RTN1,ATXN7,SCP2,TNFRSF19,SEC14L1,SGK1,FNDC3A,R3HDM2,ST6GAL1,SYBU,BTBD3,WDR47,SLC6A8,SLC8A1,CCDC88A,SLC14A1,BTBD7,RCOR3,LIMCH1,SNAP25,KIF13A,SNRPN,USP33,TRERF1,ZC3H13,CDK19,SPART,TROVE2,POGZ,SSTR2,MPRIP,RGL1,PLCB1,SYN1,ARC,SYN2,SYPL1,SYT1,MTCL1,CAMTA1,ALG1,IQCE,FBXW11,ATMIN,SIN3B,DMXL2,TRIM2,TCF12,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,DICER1,ZFPM2,TK2,CSMD1,NPL,WBP2,STXBP4,TSN,TSC1,CLHC1,SGK3,FAM155A,RICTOR,XRCC4,ZBTB14,ZIC1,ZNF711,ZNF74,CELF4,ANKS1B,FTSJ1,MAP3K12,MFF,STOX2,PRDM10,NAV3,WNK3,RGS7BP,FAM13C,ST7,PHTF2,FXR1,FRMD6,SENP7" MicroRNA hsa-miR-633:mirSVR_lowEffct hsa-miR-633:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.16E-122 2.89E-118 3.70E-120 3.41E-119 317 1838 "CLK4,NCKAP5,ACTN1,XKR4,FMNL2,GALNT16,CCDC85A,ADCY8,TMCC3,AXIN2,PLEKHH1,ADRB2,ZNF608,HACE1,KIAA1324,TXNDC16,ZNF578,SPOP,PCDH10,FAM135A,ZFAT,MAP4K3,PKP4,TNRC6C,TMEFF1,MARCH3,TMEM108,ATP1A1,RNF182,ATP6V1G2,SEC11C,NRP2,BLM,SCAPER,SGCE,IL33,CACNA1A,CABP7,KALRN,PTBP2,ISPD,CLDN10,CCK,METTL6,ENTPD6,DCLK1,MAGI1,CHGB,SOCS6,CNOT8,PLAA,CNTN1,ARMC8,LETMD1,NRG2,CLOCK,ANKRD44,ARHGEF10,OSBPL3,SUSD5,IPCEF1,VCAN,VAC14-AS1,FAM169A,DZIP3,GREB1,PUM1,BOC,DOCK4,HDAC9,ARHGAP32,KCTD8,MAML1,DAPK1,GIT2,DNAL1,ARMCX2,GSDME,MTX3,DMD,DYNC1I1,CASP8AP2,ECM2,FAM78B,DNM1L,GOLT1B,EDIL3,WDPCP,EDNRB,HIPK3,TMTC1,APH1A,KCTD3,EIF4G2,EIF5,TENM1,TMEM35A,CALCRL,RRAGB,ADGRV1,ABCA8,SCML2,ZSCAN30,SEC24B,MED12L,GTF2IRD2,FGF1,POLR1B,FGF11,FGF13,FGF14,AMOTL2,IP6K2,RGPD5,ATP13A4,C2orf88,EFCAB2,APOPT1,UFM1,PDLIM5,STAU2,SARAF,MEGF10,MTHFD2,LRRC37A6P,MSTN,CYP46A1,MMADHC,KDM2B,ZNF782,WDFY3-AS2,GPD2,BVES,LINGO1,GUCY1A1,FRMD3,ATXN2L,HSF2,SMAP1,SOWAHA,TJAP1,IL12A,INPP5B,SLC35G1,CYP27C1,LMO2,SYTL4,HECTD2,NCOA7,SMAD1,GPR155,MARK1,LYPLAL1,CHIC1,TM6SF1,MEF2C,MEIS1,MEIS2,KITLG,MMP16,ZNF680,NRBP2,MXI1,MYO5A,MYO6,RTL5,NEXMIF,NCAM2,ALDH1L2,SLC11A2,OCRL,DPY19L2P2,ETFRF1,PCDH9,ENPP2,ZNF655,FAM218A,ZFYVE21,XRN1,PLCB2,SCHIP1,ING3,PPM1B,CCDC144B,PPP2R5E,PPP3CA,PKIA,HYDIN,MASP1,QRICH1,NCR3LG1,PTK2,PTN,ZSCAN32,PTPRD,PTPRG,PTPRO,TTC13,TUG1,RAD17,FAM184A,OXR1,RBBP6,RADX,KHDRBS2,MSANTD2,RDX,ZMAT4,REV3L,UBR7,RGS12,RNASEL,ALG9,GSTCD,RPE,ARMH4,ATP8B4,ADAL,LRRK2,KCNIP1,CCDC112,ATXN2,ATXN7,FNIP1,SMPD3,CPEB3,SHC4,FNDC3A,NUBPL,PPP4R3A,SLC6A11,ARHGEF40,NAPB,ZFP1,COA1,ANKRD36,SNAP25,KIF13A,CABCOCO1,SNRPN,PDZRN3,MYO16,RBM34,DOP1A,TRERF1,KDM4C,PEG10,ZNF423,CDK19,NFASC,ZNF621,TROVE2,ERBIN,NXT2,DIP2A,KLHL7,ANKRD12,MTCL1,EXOC7,ADGRL3,IQCE,TCF4,SATB2,ZFP90,ZEB1,TRIM2,TCF12,PUM2,FRYL,TEK,FAM200B,DICER1,SIRT1,C18orf54,AP4E1,ZNF106,AKTIP,ACTR6,RIMBP2,TRIO,TRO,TRPS1,TSN,TTTY15,UGT8,ZNF709,VGF,VLDLR,WIPF1,WRN,RICTOR,GUSBP1,XRCC4,ZNF24,KCNT2,AGMO,CELF4,ZBTB38,TMEM237,ZNF189,ANKS1B,ZNF195,ZFAND5,SLC30A4,DNALI1,FIP1L1,FAM47E,FAM13C,AMN1,ST7,RTN4,KAT6A,PHTF2,FBXO36,RNF146,CPNE4,FAM198A" MicroRNA hsa-miR-485-3p:mirSVR_lowEffct hsa-miR-485-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.72E-122 3.20E-118 4.05E-120 3.73E-119 316 1827 "KCNH8,SYN3,CLK4,ABHD6,SYS1,HECW2,RTL9,OSBPL1A,NME5,OSBPL8,HFM1,C1QTNF3,ALCAM,AMPD3,ZFAT,CDC42BPA,LRCH2,PKP4,APBA2,APBB2,APC,EPB41L5,DDO,USP37,CADPS,ASPA,MARK4,NCOA1,DPY19L3,ATP6V0A1,MYOM1,MPDZ,BMPR1B,ST3GAL5,ARHGEF7,SGCE,CA8,CACNB4,CALB2,KALRN,PTBP2,CAMK2G,ISPD,SPAG9,PRC1,ZNF501,CLDN10,CCK,P2RX6,CD38,C1orf52,DGKI,CDH2,LRRFIP1,CDO1,FOXN3,CHN2,B4GALT6,NRXN3,FBXO7,ABCG2,SULT4A1,HECTD1,MAP4K4,CNTN1,ARMC8,COL4A5,SLC4A8,TBPL1,ZNF521,RBM39,SNCAIP,CSF2RA,SUSD5,SIPA1L1,SOCS5,CNTNAP2,PLXNA4,ERC2,PNPLA8,CTH,BOC,ZFYVE16,KIAA0586,TMEM170A,DNAL1,ARMCX2,ELMO1,GUCD1,POM121,SNAP91,FAM107B,RAB39B,USP3,DMTF1,DPH1,DTNA,DNAJB6,DNM1L,WDPCP,EDN3,EDNRB,PHC2,SEMA3D,TMTC1,PHF20L1,USPL1,SPEG,CDKL3,ETV1,DNAJC27,SIRPB1,EXTL2,CLVS1,MED12L,OLFM1,FGF12,SUCO,HPCAL4,SYNCRIP,AGAP3,FOXO3,FLT1,FAM49B,CAMKK2,ZNF605,KHDRBS3,STAU2,OGA,MEGF10,GABRB3,GABRG1,MTHFD2,DISC1,INPP5K,LRRC37A6P,CPLX2,MSTN,MMADHC,DBF4,SPIN1,FERMT2,TDRKH,FUT10,GPR12,GPR34,GSN,FAM19A2,RNF165,BVES,LINGO1,PSIP1,MAP4K5,RASSF8,HAS2,DDX19B,ELOVL5,HNMT,IGFBPL1,ZIC5,RBPJ,ZNF678,INSM1,JAK2,IPO5,STXBP5,PAXBP1,NCOA7,MARK1,MAT2A,MBP,CHIC1,TM6SF1,LRP1B,SHC3,AFF1,XRRA1,COL28A1,BLOC1S2,HS6ST3,MYO7A,MYO9A,NCAM2,NDP,NEFM,NFE2L2,NFYA,CNOT4,DNHD1,NTRK3,FAM225B,P2RX7,GLIPR1L2,ETFRF1,CDK18,PDE4B,PDE4D,ENPP2,PFKFB3,FAM98B,OLA1,NALCN,SCHIP1,ING3,MBOAT7,PPP2R5E,KANSL1,RANBP3L,CEP41,MAPK10,HYDIN,DCHS2,RELN,ANKHD1,BDNF-AS,ZSCAN32,ZIK1,PTPRE,PPP2R3C,SH3TC2,FAT4,ZCWPW1,RADX,RDX,GAL3ST4,RET,ZDHHC4,SLC25A36,RORB,NEK11,ARMH4,STK32B,MEG3,CLIP1,RTN1,SEMA6D,SATB1,ATXN2,SUPT20H,SGK1,SH3GL3,KIF16B,CHD9,FBXO11,FNDC3A,NLGN1,DZIP1,NUBPL,SLA,FAM81A,CCDC88A,BTBD7,ATF7IP,MAST1,IFT122,MYO16,DOP1A,BDP1,KDM3A,HECW1,KDM4C,ZBTB43,LMO3,TROVE2,ITPRID2,NXT2,ELOVL4,CEP68,RGL1,KANK1,KLHL7,ARHGEF9,NUDT10,PLCB1,COBL,MCF2L,EXOC7,TBCEL,TCF4,TPCN2,RPGRIP1L,NAT16,PCDHB7,SIK3,ZFPM2,ITGB3BP,ARL10,ERCC6L2,CSMD1,TNS1,ZNF346,STXBP4,SSBP2,UBE3A,P2RY12,ZNF17,ZNF24,ZNF28,ZNF32,TRIM9,REEP1,FSTL5,UPF3A,EMSY,MFF,EVI5,TUBA1A,ADAMTS9,FIP1L1,FZD3,RTN4,UBE3B,FXR1,FRMD6,IFT88,SENP7" MicroRNA hsa-miR-454:mirSVR_lowEffct hsa-miR-454:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.91E-122 4.98E-118 6.23E-120 5.74E-119 313 1795 "KCNH8,ASIC1,SYS1,ACTN1,ADD1,PWWP2A,PCDH19,CC2D2A,AK2,SPARCL1,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,MYH7B,PHF12,EPB41L5,TNRC6C,LGR5,IGDCC4,CDK13,ZNF582,DOCK11,KSR1,BMPR1B,SGCE,RAB29,LDLRAD4,CALB1,USP2,ENTPD6,ZMYM4,MAGI1,NOG,SRSF11,FOXN3,MS4A7,EPS15L1,FBXO7,C4orf33,QKI,HECTD1,MAP4K4,RAB26,FHL5,IQCK,AKAP5,SLC4A8,ZNF521,HAPLN1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KLHL3,SNAP91,SV2B,FAM107B,GRIN3A,NYAP1,USP3,DNAH9,MED12,CPEB2,SLC12A6,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,EIF4G2,TENM1,C3orf18,EMX2,LRRC17,GPHN,ETV1,TLR7,KATNAL1,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,AMOTL2,MEX3B,PCYOX1,ANKFY1,NOP56,JKAMP,STAU2,GABRA3,ZNF44,GABRG1,GALC,RAPGEF6,ZNF274,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,DBF4,TOX3,GPT2,ADGRA3,FUT10,GPR12,MCHR1,GPER1,PCLO,GRIA2,GRM2,LINC01089,KAT7,SOX21,GUCY1A1,MAP4K5,FAM222A,RASSF8,HAS2,FRMD3,MIER3,HLF,IGF1,NIM1K,SLC35G1,KCNN2,KIT,NCOA7,MAP2,MARK3,ADAM11,CHIC1,AFF1,ZNF680,ADAM22,MXI1,MYO5A,MYO9A,NEXMIF,IDNK,NOVA1,NPTX1,NPTX2,DPY19L2P2,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,PIK3R1,FAM216A,PDZRN4,STRN3,ING3,SH3KBP1,POU6F1,PPM1B,PRKAB2,PKIA,HYDIN,DIRAS2,RELN,VPS13C,DEF8,ZIK1,PTPRD,PTPRE,TMEM231,PPP2R3C,USP47,FAM184A,ROGDI,OXR1,RBBP6,GTDC1,FIGN,RFX3,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,ZC3H14,ZNF671,GLDN,RYR3,ZNF331,SATB1,SCN8A,SCP2,TNFRSF19,HSPA4L,PUF60,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,FAM81A,CDK5RAP3,SLC12A2,CPEB4,MAST1,RCOR3,CABCOCO1,SNRPN,FNBP1,KDM3A,TSPYL2,RBM26,ZC4H2,LARP4,STAU1,SEPT8,DIP2A,KANK1,STXBP1,SYT1,SLC37A2,TACC1,TACR1,EXOC7,PDLIM2,AGTPBP1,TBCEL,TBL1X,ATMIN,TCEA1,TCF4,SIN3B,DMXL2,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,SYNE1,PCDHB7,USP32P1,FRYL,GALNT17,RIMBP2,PARD3,NPL,DOK6,NR2C2,TRPS1,HIRA,EIF4ENIF1,UBE3A,LINC00689,TOM1L2,VLDLR,P2RY12,CLDND1,RICTOR,XRCC4,PCDH20,ZNF24,CELF4,SPIRE1,UPF3A,EMSY,EVI5,LINC02210,PRDM10,NAV3,FIP1L1,FAM47E,PDSS2,FAM13C,DOCK8,RTN4,FBXO36,CASC15,FAM219B,ADAMTSL3,JMJD1C,RNF170,NETO2,NETO1,SOCS4,JPH3" MicroRNA hsa-miR-514:mirSVR_lowEffct hsa-miR-514:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.43E-122 5.28E-118 6.52E-120 6.00E-119 306 1715 "RALGAPA1,CLK4,TMCC3,BRAP,KIAA1211,BEND6,AP2A2,MTUS1,KLHL13,PCDH19,HACE1,WDR35,SEMA6A,ALCAM,MARCH4,PCDH10,BBOX1,UNC79,FAM135A,GPRASP2,LRCH2,C6orf89,LCORL,PKP4,UPRT,NT5C3B,PHYHD1,USP37,PPP4R4,RGS20,CADPS,LINC00173,TMEM108,ATP1B3,ATP2A2,ALDH7A1,ADAM23,LINC00847,BCHE,DNAJC27-AS1,BMP7,SCAPER,C5,IL33,CA12,ISPD,CLDN10,USP6,MTMR7,MAGI1,SOCS6,MS4A7,CNOT8,C7orf61,IGLON5,ARMC8,AKAP6,MAGED1,ZNF521,FAM171B,C2CD2,CREM,GDA,SNCAIP,RGS6,LRIG1,ARHGEF10,VCAN,PPP1R16B,ERC2,APPL1,PUM1,KATNAL2,RIPOR2,DCAF8,MATR3,GIT2,DNAL1,JAKMIP2,HEPH,FBXL5,GSDME,SGSM2,DLX1,EXOG,SLC29A4,DMTF1,DPH1,DTNA,TOM1,ABCC5,DNM1L,EDN1,EDN3,FCF1,SEMA3D,TMTC1,FSD1L,EIF5,MRNIP,CALCRL,EIF1,EMX2,RCAN2,DENND4A,NCALD,ZNF549,MRPL37,KATNAL1,TAOK3,FCGR1A,CEP78,FDFT1,ZNF589,PRKAG2,MEX3B,EFCAB2,SMC2,ATP2C1,KHDRBS3,ABLIM2,OGA,MEGF10,GABRG2,ZNF234,SYT17,C15orf41,DISC1,INPP5K,IGSF5,GCNT2,MSTN,ADAM28,TNRC6A,ZNF638,GNAL,GPD2,PRUNE2,CCDC184,GPR34,PCLO,GRIN2C,FAM19A2,ZBTB49,ZHX1,FRMD5,BACH2,ELOVL5,HSPA1L,MSL1,ZNF546,LRRC25,RBPJ,KCND2,KIF5A,IPO5,STXBP5,LAMA2,STMN1,SFXN5,SYTL4,LSS,MBD1,MBNL1,LRP1B,ZNF680,HS6ST3,MYT1,HNRNPM,SFR1,NEFH,NOVA1,NPTX1,SLC11A2,NUCB2,OCRL,CHAMP1,DPY19L2P2,PCDH8,PDE1C,PDE4D,SLC10A4,SERPINI1,XRN1,PLCB2,PDZRN4,ING3,PPP2R2B,PRKAB2,PKIA,PRKAR1B,PRKCB,MAPK4,MAPK9,PRPSAP2,VPS13C,CNTLN,BDNF-AS,MTMR10,PTPRE,PTPRN2,PTPRO,FAT4,RADX,REV3L,RGS3,RIC8B,NEK11,RPL15,ZNF671,LRRK2,ATAT1,ZNF568,TRAPPC13,SEMA6D,SUPT20H,TRA2B,PPM1E,CPEB3,FHOD3,ST6GAL1,PPP4R3A,ZNF430,SLC9A5,ATF7IP,IFT122,ANKRD36,SNAP25,MBD5,LMBRD1,SNRPN,USP33,ZSWIM8,SP4,MYCBP2,TEX2,ZNF423,ZBTB43,RBM26,POGZ,SAMSN1,SSPO,ERBIN,ZSCAN29,CEP68,PHLDB1,KANK1,SYPL1,TACR1,ANKRD12,PJA1,MLST8,TAL1,TCF4,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,SIRT1,AP4E1,SLC44A1,TIAM1,RELL2,BHLHB9,BEX4,CSMD1,PIK3R5,TP53BP2,SYNPO2,AMACR,KCNE5,ANKRD20A2,TTC3,GORASP1,BCL2L13,RICTOR,GUSBP1,ZBTB14,ZIC1,ZNF708,KCNT2,TCEAL7,DPYSL5,EMSY,MFF,SLC38A1,LINC02210,HPS4,SLC17A7,PDSS2,RTN4,SMIM8,FBXO36,KLHDC1,FRMD6,IFT88,NETO1,GAN,FAM198A" MicroRNA hsa-miR-599:mirSVR_lowEffct hsa-miR-599:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-121 6.61E-118 8.06E-120 7.42E-119 305 1705 "TMEM132B,GALNT13,ESYT2,PTCHD1,PCDH19,RTL9,OSBPL8,ZNF578,SPOP,CARNS1,BIN1,LRCH2,APBB2,DDO,PHYHD1,PPFIA3,SEMA4G,CDK13,MARCH3,STK33,ZBTB10,SLC4A4,RNF182,N4BP2L1,DPY19L3,ADGRB3,ST3GAL5,DDR1,CABP7,THSD7A,KALRN,RUNX1T1,KRIT1,USP6,CBFA2T2,SCARB1,C1orf52,ZBED1,CDH2,SOCS6,PLEKHB1,TAOK2,NDST3,FBXO7,ARMC8,MYRIP,CREM,AKAP12,RGS6,OSBPL3,CNTNAP2,RASGEF1C,KIAA0040,RIMS2,USP6NL,CYBB,KIAA0408,EARS2,ZNF337,RASSF2,LONRF1,KCTD8,DGKB,PABPC5,AIF1L,GIT2,DGCR5,KIAA0753,SPOCK3,MTX3,CHRDL1,RAB39B,DMD,USP3,DNAH9,CPEB2,TOM1,DNAJB6,E2F5,EDN3,EDNRA,EDNRB,HIPK3,FCF1,TMTC1,FSD1L,PHF20L1,MBNL2,KMT5B,GOLGA7,RGS17,C3orf18,USPL1,VPS13B,IGSF6,ZNF549,TLR7,RRAGB,KATNAL1,MRVI1,F8,CLVS1,ABCA8,ACSL4,PTK2B,DLC1,STRADA,SEC24B,FGF12,FGF14,FGFR1,PRKAG2,SUCO,UBE2E3,MEX3B,FOXO3,ANKFY1,C2orf88,SPECC1,APOPT1,FAM49B,CAMKK2,ATP2C1,ST6GALNAC3,NSG1,AP4B1,MEGF10,HRASLS5,GABRG1,IQGAP2,MSTN,CYP46A1,AHDC1,MALT1,CRCP,SPIN1,GLUL,CBX1,KDM2B,GNAO1,GNG4,ADGRA3,LPAR4,GPR37,PCLO,DIDO1,PLCD4,ZNF496,LINC01089,AP4S1,UBE2QL1,PADI2,MAN1B1,DDX19B,HLF,SYNPO,LRRTM1,KCND2,KIF2A,IPO5,HECTD2,MAP6,MARK1,MATN2,MBD1,LRP1B,MEIS2,SRSF12,KITLG,DBNL,ADAM22,NRBP2,N6AMT1,NELL2,NFE2L2,NOVA1,PCBP3,OCRL,OXTR,GLIPR1L2,CNTN3,PAX6,DPY19L2P2,PRTG,GNG2,OLA1,FAM218A,ING3,SEPT4,RASGEF1B,CNTLN,MTMR10,ELOVL2,PTN,PTPRB,EML5,ZDHHC14,ZMAT4,DPF2,REV3L,MORC4,FIGN,UBR7,ZFHX4,TMLHE,ELP2,CCDC102B,SNX22,SPIN3,ATP8B4,ABCA11P,CLIP1,SATB1,ATXN7,FNIP1,STUM,SGK1,MYO18A,FHOD3,R3HDM2,NUBPL,SLA,FAM81A,BTBD3,KBTBD4,SLC12A2,BTBD7,ATF7IP,EPC1,GKAP1,SMARCA4,SNAP25,MBD5,ZNF415,PDZRN3,BDP1,DOK5,SP2,SP4,NMNAT2,KDM4C,UNC5B,PEG10,TSPYL2,RBM26,ATP10B,PBLD,TROVE2,CLSTN2,ITPRID2,STAU1,ELOVL4,NEK4,KANK1,SULF2,SEPT3,SUPT5H,COBL,SLC37A2,MTCL1,MLST8,EXOC7,TAL1,ADGRL3,RPGRIP1L,SYNE1,DOCK9,OBSL1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ITGB3BP,AKTIP,TK2,TMPO,RIMBP2,ZNF346,PDSS1,FAM155A,UGT8,FLRT2,PLEKHH2,ZNF709,BCL2L13,KCNK12,XRCC4,MICU3,KCNT2,LYPD6,FSTL5,EMSY,SLC38A1,NAV3,PARP11,HNRNPA3,FBXO36,SNX14,NETO1,SOCS4" MicroRNA hsa-miR-433:mirSVR_lowEffct hsa-miR-433:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-121 1.04E-117 1.25E-119 1.15E-118 310 1765 "KCNH8,AS3MT,C3orf14,KDM5D,TMEM132B,TMCC3,AXIN2,USP31,ADRB2,BEND6,SLC24A4,PCDH19,OSBPL8,CC2D2A,SEMA6A,ALCAM,LRCH2,SUGT1P4-STRA6LP-CCDC180,UPRT,BCAS1,TNRC6C,SHROOM2,CADPS,SLC4A4,DPY19L3,ATP6V0A1,ADGRB3,ZNF599,PROM1,BMPR1B,DST,NAE1,CA8,CACNB4,KALRN,CAMK2B,CBR1,CBS,USP6,MTMR7,C1orf52,ZBED1,L3MBTL4,LOC730101,MAGI1,CCPG1,CFL2,FOXN3,ASIC3,SLIT2,NRXN3,CLCN3,CLTC,FBXO7,FAM19A5,QKI,HECTD1,FHL5,CNN3,AKAP7,COL9A1,SMARCAL1,BAG4,ANKRD44,CLIP3,CRYM,CSF1,OSBPL3,IPCEF1,PDE4DIP,APPL1,PHF14,PLCXD3,CTH,KIAA0408,GPRASP1,ARHGAP32,ZNF337,KCTD8,TMEM170A,PABPC5,BRINP1,DNAL1,ARMCX2,FBXL5,KIAA0319,TMEM130,DDX46,PLPPR4,MTX3,NR1D2,DOCK2,EDIL3,EDN3,EDNRA,HIPK3,TMTC1,FSD1L,YAF2,PHF20L1,MRO,TENM1,ETV1,SIRPB1,EYA1,ARMCX1,TUBB3,DLC1,CEP78,FCGR3A,ZSCAN30,FGF1,OLFM1,FGF11,FGF13,POLK,SYNCRIP,ANKFY1,SLC37A3,AFF2,C2orf88,TMEM175,NBEA,UFM1,FAM49B,ZNF605,STAU2,AP4B1,TVP23A,OGA,FYB1,MEGF10,HRASLS5,LRRC37A6P,KIAA1841,SULT1C4,WASHC2A,ADAM28,MALT1,TXNL4A,HPGDS,GPT2,ADGRA3,LILRB4,PRUNE2,FUT10,STON1,PCLO,STMN2,PLCD4,PLPP7,ADAMTS13,CACFD1,GRM2,RABL2A,ADAMTS6,GUCY1B1,SLC2A6,MAP4K5,ATOH8,HAS2,UBE2QL1,TOX2,PACSIN2,MAN1B1,HLF,ELOVL5,NEGR1,CELF5,IRF8,IDH3A,SOWAHA,IGF1,LRRCC1,INSM1,KCNN2,KIF5A,LIG4,LMO2,GPR155,MARK1,MATN3,MBD1,MBNL1,MBP,CHIC1,MEIS1,MEIS2,AFDN,SAMD5,N6AMT1,ZNF862,ZC3H12B,VWA2,CNOT4,NPY,NOVA1,IGSF11,CHAMP1,CLDN11,GLIPR1L2,PAX6,PFKFB2,OLA1,DUSP26,PIK3C2A,RETREG1,MTRF1L,SCHIP1,POU6F1,RASGEF1B,PRKCB,MAPK9,VPS13C,TMEM260,PTPN13,PTPRB,PTPRD,PTPRN2,PTPRO,NKAIN1,ZNF615,SLC25A48,USP47,ZNF793,SH3TC2,SUSD4,RASGRF2,KHDRBS2,ZDHHC4,SLC25A36,PBRM1,ZFHX4,TMLHE,ALG9,GSTCD,RORB,ARMH4,GLDN,LRRK2,TRAPPC13,DGLUCY,SARS,ATXN2,SCP2,ZFP30,ASAP3,FNDC3A,FHOD3,ST6GAL1,SLA,BTBD3,EPN2,KANSL3,SLC14A1,TET1,ANKRD36,MBD5,CMTR2,LMBRD1,NMNAT2,UHRF1BP1L,SPP1,TSPYL2,ITPRID2,SST,NXT2,ZSCAN29,KANK1,SYPL1,TACR1,TAL1,TBCEL,DMXL2,TRIM2,CLASP1,SZT2,SYNE1,PCDHB10,NSD1,USP32P1,HIF3A,C18orf54,AP4E1,SLC44A1,TIAM1,KAT6B,NPL,DOK6,SYNPO2,AMACR,TRPS1,TSN,SSBP2,CCDC14,ZNF28,MKRN3,AMZ1,ZSCAN26,CADM2,LINC02210,STOX2,ADAMTS9,TMEM178A,GAL3ST3,NAV3,FAM13C,KAT6A,IFT88,NETO1" MicroRNA hsa-miR-491-5p:mirSVR_lowEffct hsa-miR-491-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.98E-121 1.67E-117 1.99E-119 1.83E-118 318 1861 "ACADM,ACHE,EMILIN3,TMCC3,ADD1,PLEKHH1,FZD9,KIAA1211,LRFN2,MTA3,SLC24A4,INTS2,HECW2,C1QTNF3,SEMA6A,ALCAM,LTBP4,SYT13,OGT,GAS7,APLP1,CDK10,MADD,ARRB1,ARRB2,PDE8B,MARCH3,NUMB,ATP6V1G2,ATP6V0A1,TTLL9,ADGRB1,BCHE,RGS11,GPR146,KSR1,BMPR1B,DST,SYNJ1,ARHGEF7,FUBP1,MTMR2,AP1M1,CAMK2B,SPAG9,PRC1,CERS5,CBFA2T2,CD38,ENTPD2,NOG,CFL2,ASIC3,TAOK2,LHX2,EPS15L1,CPNE6,CLTC,VAX2,IGLON5,CNTN1,FAM149A,COL11A2,TBPL1,ENTPD4,NCOR2,GDA,CLIP3,CS,SNCAIP,CSF1,SEC24C,SUSD5,KIAA0040,CTH,ZNF337,LIN54,MAML1,IST1,DGKG,SPOCK2,ELMSAN1,DCTN1,C2CD2L,KIAA0319,TMEM130,PLPPR4,SACS,SPOCK3,SGSM2,DMPK,DRP2,TOM1,E2F5,CNNM1,YAF2,PHF20L1,APH1A,EGFR,MRO,EGR3,ING4,ELN,USPL1,VPS13B,EPB41,SLC43A2,SRRM1,ERBB2,NCALD,SPEG,ETV1,MRVI1,PTK2B,TAOK3,CHST15,FCGRT,FKTN,ZSCAN30,KAT8,SPSB4,MEX3B,HPCAL4,AGAP2,AGAP3,RGPD5,EFCAB2,PDLIM5,CAMKK2,STAU2,DOT1L,SDCBP2,NEURL4,TRAF3IP2,GALC,B4GALNT1,GHDC,IQGAP2,SIGLEC8,ALDH1L1,SRCAP,SESN1,GGT7,GHR,CRCP,GLI2,LNX1,ADGRA3,GPD1,PCLO,STMN2,FAM19A2,RNF165,RABL2A,FAM107A,UBE2QL1,PADI2,NXPH3,ATXN2L,MIER3,HLF,CPT1C,LRRC75A,SHISA6,CELF5,SMAP1,ICA1,MSL1,IDH3B,MYLK2,LRRC25,TJAP1,IL6R,IL6ST,FAM69A,ITPKA,METTL21A,KCNH2,KCNN3,KIF5A,A1BG-AS1,L1CAM,HECTD2,MEIS1,MEST,POC1B,DBNL,PTOV1,RTL5,ZNF862,HNRNPM,NOVA1,CHAMP1,DPY19L2P2,GPR85,ZDHHC8,PIK3R1,PKM,FAM216A,SLC25A23,PURG,EXOSC10,EPB41L4B,POU6F1,PPARA,KANSL1,CEP41,PRKAR1B,PRKCB,MAPK4,DIRAS2,DCHS2,MASP1,WBP1L,GDPD2,CNTLN,TMEM260,CASTOR1,PTPRH,NKAIN1,CEP97,SLC25A48,CCDC40,RASGRF2,ZDHHC14,DPF2,GTDC1,ZDHHC4,RGS12,PRIMA1,SLC25A36,RIC8B,CCDC82,SETD5,KLHDC8A,ARMC5,CARF,CCDC25,RPE,SNX22,BAALC,GLDN,SGSM1,ST6GALNAC6,NCBP3,ZNF331,PRCD,FNIP1,TNFRSF19,CASC3,FOXRED1,R3HDM2,FAM81A,BTBD3,SLC6A8,SLC11A1,ELMO2,BTBD7,CDK5RAP2,MBD5,CABCOCO1,SNRPN,KDM4B,SP2,ZSWIM8,MYCBP2,PEG10,SPTB,CLSTN2,MPRIP,STAC2,STX1A,SEPT3,PLCB1,SYN1,SYP,PJA1,CAMTA1,EXOC7,DMXL2,CUX2,TPCN2,PCDHB15,SLC19A3,SIK3,CYB561A3,RNF216P1,ITGB3BP,LRRC8A,R3HDM1,TNS1,RASD2,TPM2,PDSS1,DCBLD1,RUSC1,TSN,HSPBP1,SLC35A4,CLEC2L,UBE3A,PLPPR2,TOM1L2,WIPF1,CLIP2,ZNF74,NDRG4,CELF4,ANKS1B,EMSY,PRTFDC1,PRDM8,PCBP4,CASC15,NHSL1,KLHDC1,LAS1L,PRRT4" MicroRNA hsa-miR-18a:mirSVR_lowEffct hsa-miR-18a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.47E-121 2.50E-117 2.94E-119 2.71E-118 298 1634 "ASIC1,KLHL32,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,AXIN2,ESYT2,DPY19L2P4,RTL9,HACE1,KIAA1324,AK2,SEMA6A,USP35,FAM135A,SYT13,DPP10,ANK2,LCORL,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,UPRT,NT5C3B,APOC2,AQP6,CDK13,NUMB,CHID1,EIF4G3,DPY19L3,ADGRB2,LINC00847,BBS2,SEC11C,DST,SYNJ1,MYRF,CACNB4,PTBP2,CAMK2G,HIP1R,RHBDL1,NFS1,LDB2,CD86,CCPG1,TAOK2,NRXN3,TPP1,DGCR9,VAX2,SULT4A1,CNR1,ABI3BP,FAM171B,CLOCK,CRY2,ANKRD44,CSF1R,SEC24C,CSNK1E,SIPA1L1,SLITRK5,PHF14,CTH,MYADM,DCAF8,TBC1D5,KIAA0586,GIT2,ZNF804A,DGCR5,MYEF2,TMEM130,PLPPR4,SNAP91,DNM1,DYNC1I1,SLC12A6,ABCC5,E2F5,EDNRB,PHC2,EGFR,MBNL2,KMT5B,TNK2,TMEM35A,MFSD10,GPHN,ERBB2,DENND4A,ANKMY1,SIRPB1,CHST15,FKTN,ZSCAN30,ZNF589,GORAB,FGFR3,UBE2E3,SYNCRIP,FLT1,PSD2,EFCAB2,NBEA,SMC2,UFM1,STAMBP,CAMKK2,HHIPL1,TPPP3,GABRB3,GABRG2,IP6K3,ZNF559,DISC1,LRRC37A6P,KIAA1841,ALDH1L1,ADAM28,ZNF276,COPS8,SPIN1,WDFY3-AS2,ADGRA3,GPD1,TDRKH,DIDO1,PLCD4,ADAMTS13,ZNF496,RNF165,PACSIN2,ATXN2L,TNFAIP8L3,MIER3,VSIG4,ELOVL5,HMGCL,AGFG1,DHX35,MSL1,FAM95B1,RBPJ,LRRCC1,METTL21A,KCND2,KCNN2,KIT,IPO5,STXBP5,KTN1,SYTL4,HECTD2,ZNF667-AS1,MAP4,MARK1,MAT2A,ADAM11,MEF2C,MEIS1,TAGLN3,NOVA1,NTRK2,NTRK3,OGG1,LOC100128398,OPRL1,PAX6,PCDH9,CDK18,SLC10A4,GNG2,PFKFB2,PFKFB4,PCDH18,ANKRD16,EPB41L4B,POU6F1,PPM1B,PPP2R5E,EPDR1,BCAS3,WBP1L,NCR3LG1,BDNF-AS,TMEM260,ZSCAN32,PTPN13,EML5,PTPRE,PTPRG,PTPRO,PID1,CCDC40,SH3TC2,ZCWPW1,REV3L,RGS4,RGS12,LGI2,ALG9,GSTCD,ROBO1,KIRREL1,ELP2,PCMTD2,EPHA10,BAALC,SGSM1,ADAL,LRRK2,KCNIP1,CLIP1,FAM192A,SAFB,SEMA6D,SCP2,SMPD3,SCAF8,FERMT1,FNDC3A,ABLIM3,SLC2A5,SEPHS1,CCDC88A,CPEB4,ARFGAP1,MAST1,CDK5RAP2,IFT122,ANKRD36,SNCA,SNRPN,MYO16,FNBP1,ZSWIM8,CLASP2,CLSTN2,POGZ,MESP1,SSTR2,SSPO,ZSCAN29,NSFL1C,NECAB1,PLCB1,ARC,SYN2,SYPL1,DNMBP,KLHL4,TRIM2,FAM189A1,PCDHB4,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ERCC6L2,TMPO,CSMD1,CABIN1,TNS1,TPM2,WBP2,CHST5,UBE2H,OSBP2,FLRT2,ZNF709,VLDLR,ZIC2,ZNF540,ZNF154,REEP1,POLR3H,TFIP11,RNF103,GAL3ST3,PARP11,PDSS2,ST7,UBE3B,TRAM2-AS1,PRRT4" MicroRNA hsa-miR-218:mirSVR_lowEffct hsa-miR-218:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.51E-121 3.64E-117 4.22E-119 3.89E-118 312 1796 "ASIC1,EMILIN3,NCKAP5,SYS1,KLHL32,TMEM132B,ELFN2,ADD2,BRAP,PLEKHH1,KIAA1211,RNF150,DPY19L2P4,KLHL13,KCTD16,CC2D2A,HFM1,SEMA6A,USP35,ABCD2,MARCH4,TRMT9B,AMPD3,CDC42BPA,DDO,USP37,SHROOM2,LINC00173,CDK13,ATP1B3,N4BP2L1,DPY19L3,MYOM1,ADAM23,LINC00847,KSR1,BMPR1B,SYNJ1,SYNJ2,ARHGEF7,FUBP1,CACNA1I,CA12,CACNB4,CAMK2B,SPAG9,PRC1,KRIT1,CD86,DGKI,CDH2,LOC730101,MAGI1,CFL2,FOXN3,CLCN3,C4orf33,IQCK,LETMD1,AKAP5,CNRIP1,SH2B1,HAPLN1,CSF1R,OSBPL3,SOCS5,VAC14-AS1,PDE4DIP,SLITRK5,KIAA0040,PHF14,USP6NL,CCDC144A,KIAA0408,GAPVD1,DCAF8,ZFYVE16,RASSF2,TM9SF4,KIAA0586,DGKB,ARMCX4,ZNF804A,ZBTB24,HEPH,C2CD2L,KLHL3,ZC3H11A,USP3,DOCK2,SLC12A6,DPP6,DTNA,DTNB,DNAJB6,E2F5,E2F6,EDNRA,SEMA3D,PHF20L1,AASS,EPHB1,STX2,NRN1,CLVS1,ABCA8,TMEM132C,TAOK3,FCGR3A,STRADA,FDFT1,SEC24B,GTF2IRD2,FGF14,MEX3B,HPCAL4,PCYOX1,FLT1,NOP56,WDR83,HVCN1,CAMKK2,CGREF1,CSPG5,DOT1L,HRASLS5,GABRG1,ZNF559,C15orf41,DISC1,PCDH17,GGTA1P,PPARGC1A,TXNL4A,TNRC6A,FERMT2,GPD2,GPR12,LPAR4,DIDO1,SERP2,GRIN2D,GRM8,RNF165,GUCY1A1,GUCY1B1,MUM1,RASSF8,TOX2,MAN1B1,USP51,HSF2,IDH3A,ZIC5,RBPJ,LRRCC1,SCIN,IL6ST,IL12A,KCNH2,KCNN2,KCNN3,LAMP2,SYTL4,MAN2A2,SCAMP5,MID1,ADAM22,HS6ST3,MYO6,ZC3H12B,NFIX,NOVA1,PCBP3,SLC11A2,NRCAM,NTRK2,NUCB2,OXTR,GPR137C,CNTN3,PAX6,DPY19L2P2,PDE4B,PDE4D,GPR85,OLA1,ZDHHC8,DUSP26,CCSER2,RETREG1,PURG,LRP12,SCHIP1,SH3KBP1,PPARA,RASGEF1B,PKIA,DIRAS2,QRICH1,CNTLN,BDNF-AS,PTN,TMEM260,PTPRB,STRC,SH3TC2,ZMAT4,RET,RFX2,KLHDC8A,ALG9,CARF,CCDC25,FBXW7,BAALC,GLDN,ABCA11P,ATAT1,DGLUCY,SALL1,SCP2,SMPD3,SEC14L1,GALNT10,SCAF8,SH3GL3,ELMO2,ATF7IP,TET1,ANKRD36,MBD5,SNRPN,FAM219A,BDP1,SOX11,ZSWIM8,NMNAT2,PEG10,SPTAN1,ATP10B,ZC4H2,SS18,ZSCAN29,ELOVL4,NEK4,TTBK2,RHBDL3,COBL,ANKRD28,C12orf76,TACC1,ANKRD12,ALG1,ADGRL3,TBCEL,TCF4,ZFP90,TPCN2,TRIM2,PHF24,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA3,PCDHA2,PCDHA1,FAM200B,PMS2CL,ZFPM2,C18orf54,ITGB3BP,NR2E1,PARD3,DOK6,NR2C2,SMUG1,TRIO,TSN,TTTY15,TTC3,TUBB1,UBE3A,OSBP2,VLDLR,VSNL1,RICTOR,ZFP37,ZNF711,ZNF19,ZFP41,FSTL5,PCBP1-AS1,PRTFDC1,SLC38A1,EVI5,STOX2,PRDM8,TMEM178A,MDH1B,ITM2C,PDSS2,RGS7BP,SMIM8,HNRNPA3,ACTR3B,ADAMTSL3,NLRP3,NETO1,SOCS4" MicroRNA hsa-miR-1226*:mirSVR_lowEffct hsa-miR-1226*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.57E-121 3.67E-117 4.22E-119 3.89E-118 326 1961 "SYN3,ACHE,SYS1,TMEM132B,GALNT16,ADCY6,ADD1,ADD2,PTCHD1,ADRA1D,AP2A2,ZNF608,RTL9,CARNS1,AMPD2,ZFAT,CDC42BPA,EP400,FGD2,C6orf89,CCDC146,APBA2,UPRT,CDK13,MARCH3,MARK4,ZSCAN18,TMEM108,ATP6V0A1,ADAM23,CFLAR,JAZF1,BAIAP3,IL33,CFAP410,CA4,CACNA1A,CACNA1B,CACNB4,CABP7,CAMK2G,CAPN3,CAST,HIP1R,CLDN10,P2RX6,SEPT7,ZBED1,DCLK1,LARGE1,FOXN3,ASIC3,PLEKHB1,TAOK2,RAB33A,CLCN3,DGCR9,MAP4K4,IGLON5,CNN3,ARHGEF6,AKAP7,AKAP5,SLC4A8,CNRIP1,SLC35F1,PREPL,CREM,HINFP,CSF1,CSF2RA,SEC24C,ARHGEF10,CSNK1E,CNTNAP2,DZIP3,GREB1,RIMS2,CYBB,HDAC9,GAPVD1,DCAF8,CENPL,INTS1,IST1,SCRN1,IP6K1,DBI,RUSC2,C2CD2L,POM121,SGSM2,KIF19,HS3ST2,RPS6KL1,SHANK1,DMTF1,DPH1,SLC25A18,DTNB,TOM1,FARSB,EDNRA,FAM13A,APH1A,EGFR,EIF4G2,PLEKHA1,STARD3NL,COQ7,ENPP6,STX2,MRPL37,RASL12,ZNF461,TUBA1B,PTK2B,CHST15,FKTN,KAT8,ZNF589,FGF1,FGF12,FGF13,FGFR1,BAIAP2,TMEM164,PSD2,FOLR2,TMEM107,SMC2,ZNF605,ERGIC3,STAU2,DOT1L,BRSK1,OGA,GABRA3,GAD1,B4GALNT1,ERAP1,DISC1,TUBGCP4,MSTN,CYP46A1,GFRA2,USP19,ZNF276,TNRC6A,GLUL,ZNF638,CBX1,DCLK2,LOXL3,PRRC2B,FUT10,CCDC184,ADAP1,CNTRL,ADAMTS13,RNF165,AP4S1,SLC2A6,MAN1B1,TNFAIP8L3,MIER3,SYNPO,HNMT,CPT1C,HSPA1L,NKD1,GAREM2,ZIC5,ITPKA,KCNJ5,KCNK3,KCNN2,CREG2,A1BG-AS1,L1CAM,LAMP2,SFXN5,MAN2A2,ZFYVE27,MAP4,AQP11,MBD1,TM6SF1,MEF2C,MPP2,ADAM22,NRBP2,MX1,LYRM9,MYO7A,CCDC13,NF1,NME4,DNHD1,PCBP3,SMIM11A,NTRK2,NUCB2,IGSF11,CNTN3,PCSK1,CDK18,PDE4D,CYTL1,PFKFB2,PIK3R1,SNX10,ZFYVE21,PLEC,SMIM7,PLTP,ING3,RETREG2,SEPT4,FA2H,DIRAS2,NDUFS7,WBP1L,PIGG,CNTLN,NCR3LG1,BDNF-AS,MTMR10,TMEM260,PPP2R3C,SLC25A48,USP47,CCDC40,RASGRF1,RGS12,KCTD17,KIF7,RIC8B,CCDC82,C12orf49,CARF,PCMTD2,ATP8B4,KCNIP3,CLIP1,STX1B,NCBP3,SEMA6D,SCN2B,SCP2,COPZ1,FAM102A,KIF16B,AMBRA1,FNDC3A,PKNOX2,SLC8A1,SIRT2,SLC11A1,SLC12A4,ZNF334,SLC14A1,ELMO2,ANKRD36,MAPKBP1,FAM126B,RBM34,KDM4B,FNBP1,ZSWIM8,PEG10,SPTAN1,IQSEC2,ZBTB43,DDN,SPART,NFASC,NEK4,SEPT3,JMJD6,SYN2,SYP,MMS19,CAMTA1,PDLIM2,ADGRL3,SMG6,NEU4,KIAA0930,TCF12,SYNE1,PHF24,TNS2,HIF3A,CYB561A3,RNF216P1,DICER1,AP4E1,THRA,ERCC6L2,TNS1,CDK20,RGMB,SYNPO2,SMUG1,TRO,STXBP4,TRPS1,TSC1,ZKSCAN5,UBE2H,GORASP1,OSBP2,TSPAN11,ZBTB14,TRIM9,CELF4,FSTL5,ZNF184,ZSCAN26,DOCK8,KAT6A,TMEM63C,TIGD6,GAN,PRRT4" MicroRNA hsa-miR-19a:mirSVR_highEffct hsa-miR-19a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.14E-120 6.37E-117 7.24E-119 6.66E-118 295 1606 "ABR,NCKAP5,ACTN1,KIAA1211,ESYT2,BEND6,DPY19L2P4,HECW2,WDR35,SRPX,PCDH10,FAM135A,CDC42BPA,LRCH2,MAP4K3,PHF12,APAF1,USP37,LINC00173,CDK13,STK33,ZBTB10,CCAR2,STX16,ZNF583,ATP6V0A1,BARD1,NRP2,ST3GAL5,JAZF1,C5,IL33,CA4,THSD7A,CALM1,KALRN,CAST,RUNX1T1,PRC1,USP6,CBFA2T2,SEPT7,ZMYM4,LRRFIP1,EVI5L,TIGD7,CCPG1,CFL2,SRSF11,PLAA,CLTC,QKI,CNGA3,FHL5,CNTFR,AKAP7,ARMC8,FAM149A,LETMD1,COX4I1,AHCTF1,SMARCAL1,ZNF521,SLC35F1,CLOCK,GDA,CS,CSF1,LRIG1,SOCS5,PDE4DIP,APPL1,PHF14,PPP6R2,DCAF8,LONRF1,DAPK1,IP6K1,GIT2,DBN1,PITPNC1,ZNF804A,ZC3H11A,DDX46,SACS,WDR20,DLX1,USP3,CPEB2,ARRDC4,DTNA,ECM2,AASDH,EBF1,EDIL3,EDNRB,HIPK3,YAF2,FAM13A,PHF20L1,EGR3,PLXNC1,EIF4G2,CERCAM,EMX2,ENPP6,NCALD,NRN1,ABCA8,ACSL4,CORO2B,FER,MED12L,OLFM1,FGF12,FGF13,SUCO,FOXF2,SYNCRIP,FLNC,FLT1,NBEA,ATP2C1,NSG1,FYB1,GABBR1,SIGLEC8,ARFIP1,ADAM28,MALT1,CRCP,CBX1,MAP7D2,FERMT2,PRUNE2,GPR34,GRB10,KAT7,ELOVL5,ZIC5,ZNF678,FAM69A,KCND2,CREG2,MATN2,MATN3,MBNL1,MID1,ZNF680,BLOC1S2,N6AMT1,MYCN,MYO9A,ZNF862,NCF2,IDNK,NME4,CNOT4,TBC1D25,OCRL,OXTR,PCSK5,PDE1C,PDE4D,SLC10A4,CCSER2,JAKMIP1,MAPKAP1,STRN3,LRP12,SCHIP1,SH3KBP1,POLR2F,MINDY2,PPM1B,PPP2R5E,PRKACB,HYDIN,RELN,PSD,MTMR10,ZIK1,PTPRD,CASTOR1,PTPRG,TMEM255A,RAD51D,RASGRF2,RBBP8,RET,GTDC1,SLC25A36,SETD5,GSTCD,ROBO2,STK32B,LRRK2,ABCA11P,CLIP1,RTN1,ATXN7,LRFN5,TNFRSF19,SEC14L1,SGK1,FNDC3A,R3HDM2,ST6GAL1,SYBU,NLGN1,BTBD3,WDR47,SLC6A8,SLC8A1,CCDC88A,SLC14A1,BTBD7,RCOR3,LIMCH1,SNAP25,KIF13A,SNRPN,USP33,TRERF1,ZC3H13,CDK19,SPART,TROVE2,POGZ,SSTR2,MPRIP,RGL1,PLCB1,SYN1,ARC,SYN2,SYPL1,SYT1,MTCL1,CAMTA1,ALG1,IQCE,FBXW11,ATMIN,SIN3B,DMXL2,TRIM2,TCF12,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,DICER1,ZFPM2,SLC44A1,TK2,CSMD1,PARD3,NPL,WBP2,STXBP4,TSN,TSC1,CLHC1,FAM155A,USP1,RICTOR,XRCC4,ZBTB14,ZNF711,KCNT2,ZNF74,CELF4,ANKS1B,FTSJ1,MAP3K12,MFF,STOX2,PRDM10,NAV3,FIP1L1,WNK3,RGS7BP,FAM13C,ST7,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-let-7f:mirSVR_lowEffct hsa-let-7f:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-120 8.80E-117 9.88E-119 9.10E-118 311 1790 "AS3MT,GALNT16,GALNT13,PLEKHH1,UNC5A,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,LCORL,PHF12,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM15,MPDZ,MTMR2,CA12,CACNB4,PTBP2,CAST,NFS1,ZNF501,USP6,SLC16A4,CD86,LRBA,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,ASIC3,CHN2,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,TRIM69,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,DCAF4,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,PDCD6IP,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,PHF20L1,EBI3,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,EPB41L2,EPHB1,RABEPK,NCALD,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,GTF2IRD2,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,SULT1C4,GHR,PPARGC1A,LYVE1,RUNDC3A,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,RABL2A,LINGO1,HAS2,HLF,HMGCL,HMGCR,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,MYO9A,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RY1,CNTN3,PAX6,PCDH9,PCSK1,PCSK5,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PKD1,PLCB2,TRHDE,SCHIP1,RANBP3L,PRKACB,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,PTPRG,NKAIN1,TUG1,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,KIAA0895L,PTGR2,MEG3,TRAPPC13,ATXN2,SEC14L1,CASC3,STUM,FOXRED1,HSPA4L,SH3BP2,CPEB3,ST6GAL1,WDR37,BTBD3,EPN2,FAM214B,KDM4D,ATF7IP,CPEB4,MAST1,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,TSPYL2,MCF2L2,RBM26,DDN,POGZ,ITPRID2,PLCB1,SLC37A2,FAM208A,PDLIM2,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,AP4E1,ARL10,TIAM1,TK2,ERCC6L2,NPL,CHST5,RGMB,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,ZNF709,WIPF1,ZNF781,PCDH20,ZNF28,EML6,MEIS3,FIP1L1,TRIM16L,ST7,UBE3B,KAT6A,CASC15,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-630:mirSVR_lowEffct hsa-miR-630:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-120 1.38E-116 1.54E-118 1.42E-117 324 1946 "CLK4,KDM5D,FMNL2,TMEM132B,GALNT16,GALNT13,ADD1,KIAA1211,BEND6,SLC24A4,AP2A2,HECW2,WDR35,TXNDC16,CC2D2A,AK2,HFM1,ADGRF5,ALCAM,CEP126,ARHGAP20,PCDH10,UNC79,SUGT1P4-STRA6LP-CCDC180,APAF1,APBB2,APC,EPB41L5,VAT1L,USP37,SHROOM2,ARNTL,RGS20,PLA2G4C,ASPA,NUMB,ATP2A2,RNF182,CARMIL3,BACH1,LINC00847,BBS2,MPDZ,BCL7A,GPR146,DST,ST3GAL5,SYNJ2,ARHGEF7,NAE1,CALB1,PTBP2,VXN,RUNX1T1,METTL6,USP2,ZMYM4,CLGN,NPIPA1,SRSF11,CHN2,SLIT2,LHX2,NRXN3,PLAA,FBXO7,QKI,LY86,CNTN1,AKAP7,ARMC8,FAM149A,AKAP5,ABI3BP,RCHY1,RTTN,ZFP28,CPS1,CREM,RBM39,CSF2RA,ARHGEF10,SUSD5,IPCEF1,UBXN2A,PHF14,RIMS2,MATR3,KIAA0586,KCTD8,DGKB,AIF1L,ARMCX4,PITPNC1,SPATA2,DGCR5,MFAP3L,MTX3,WDR20,EXOG,RAB39B,DNAH9,DMTF1,ARRDC4,DTNA,DNAJB6,DNM1L,E2F5,E2F6,WDPCP,EDNRB,ANKRD46,TMTC1,MBNL2,EIF4G2,EIF5,PAN3,SRRM1,KATNAL1,EZH1,FAM198B,ZNF461,RPS6KC1,ACSL4,FCGR1A,CEP78,FECH,SEC24B,POLR1B,FGF11,SUCO,SCARA3,IP6K2,PCYOX1,SYNCRIP,EVL,SEMA4D,ANKFY1,SMC2,UFM1,ZNF605,KHDRBS3,ST6GALNAC3,GALNT15,GABRG1,GAD1,FAM120B,GALC,RAPGEF6,GCNT2,MSTN,GDF9,MMADHC,GHR,DBF4,TOX3,GLUL,HTATSF1,LUZP2,FERMT2,TDRKH,GPR37,CLASRP,FAM19A2,ZBTB49,IRAK3,HAS2,PADI2,DDX19B,SYNPO,USP51,TCEAL6,IDH3A,GAREM2,RBPJ,KIAA1755,SCIN,ZNF678,KCNN2,KHK,IPO5,STXBP5,CYP27C1,SYTL4,GPR155,MAP2,MARK1,MARK3,MBNL1,CHIC1,TM6SF1,MEIS1,AFF1,MPP2,ZNF680,LAYN,MYO9A,NEK1,NFE2L2,NUCB2,CNTN3,PRTG,PDE4D,NLGN3,NALCN,PLCL1,PCDH18,MTRF1L,TRHDE,STRN3,EPB41L4B,FA2H,CCDC144B,PPP2R2B,LRRN3,RANBP3L,PRKACB,CNTLN,PTK2,SPDL1,ZIK1,PTPRB,PTPRE,TTC13,TUG1,CCDC40,SH3TC2,REV3L,RGS4,EXD2,ROBO2,NEK11,ARMH4,RPS20,CLIP1,CCDC112,TRAPPC13,SAFB,SCP2,RASA3,SCAF8,KIF21A,SH3GL3,FERMT1,FBXO11,FNDC3A,DZIP1,ST8SIA1,ANKRD6,SLC2A5,FAM214B,CCDC88A,SLC12A2,ELMO2,ZNF667,SMARCD3,RCOR3,PDZRN3,USP33,PDZD2,SP4,SPP1,ZBTB43,MCF2L2,PBLD,ZC4H2,SS18,ADHFE1,STX1A,NUDT10,ANKRD28,TAF9,AGTPBP1,TCEA1,SIN3B,DMXL2,SATB2,ZEB1,DOCK9,SLC19A3,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,SLC44A1,NR2E1,R3HDM1,CSMD1,C9orf85,DOK6,PDSS1,TRO,STXBP4,TTTY15,ZKSCAN5,HIRA,RPRM,FAM155A,WIPF1,XRCC4,TRIM9,MKRN3,ZSCAN26,ZFAND5,SLC30A4,EMSY,PRTFDC1,SLC38A1,HPS4,MDH1B,PPP1R3F,FAM47E,WNK2,FZD3,KAT6A,ACTR3B,TIGD6,FXR1,FAM181A" MicroRNA hsa-miR-377:mirSVR_highEffct hsa-miR-377:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.09E-120 2.29E-116 2.52E-118 2.32E-117 297 1636 "XKR4,TMCC3,ADD2,PWWP2A,AP2A2,INTS2,CC2D2A,SPOP,ALCAM,PCDH10,AMPD2,NT5C3B,BCAS1,LGR5,MADD,MARCH3,NCOA1,NUMB,RASL11B,RNF182,BARD1,BBS2,NRP2,PROM1,SYNJ1,MTMR2,JAZF1,WASF1,IL33,CA8,CACNA2D1,CACNB4,PTBP2,CAST,SPAG9,RUNX1T1,USP6,CACNA2D2,CFL2,SRSF11,B4GALT6,CNOT8,RAB28,QKI,HOMER3,ARMC8,AKAP6,ZFP28,CSF1,CSNK1G3,VAC14-AS1,PLXNA4,DZIP3,PITPNM3,ERC2,APPL1,PHF14,PUM1,HDAC9,GAPVD1,KIAA0586,IP6K1,ELMO1,KIAA0319,KLHL3,RHOBTB1,PLPPR4,CHRDL1,DMD,DNM1,CDON,DTNA,ECM2,MAMLD1,DNAJB6,AASDH,EDNRB,ANKRD46,HIPK3,YAF2,TENM1,PCOLCE2,C8orf37,VPS13B,EPB41,ENPP6,DENND4A,CLVS1,FAM198B,ACSL4,SCML2,DLC1,SPSB4,FGFR1,TMEM164,AMOTL2,SLC37A3,JKAMP,TRMO,NBEA,PDLIM5,CELF1,STAU2,SARAF,GAD1,GALC,IQGAP2,DISC1,KIAA1841,SESN1,RUNDC3A,HPGDS,GLYR1,MSL3,ZNF638,DCLK2,ZNF782,PRUNE2,TDRKH,PLCD4,RNF165,PSIP1,RASSF8,PADI2,NCKAP1L,ELOVL5,HMGCR,NEGR1,MSL1,ZIC5,RBPJ,ITGAM,KIF2A,IPO5,STXBP5,LAMP2,LIG4,SFXN5,HECTD2,NCOA7,MARK3,MAT2A,MBD1,MBNL1,TM6SF1,AFDN,MMP16,MSR1,MXI1,NFE2L2,NPY,NOVA2,DNHD1,SLC11A2,NRCAM,OPA1,PCDH8,PCSK1,PCSK5,PDE3A,PDE4B,GPR85,GNG2,DUSP26,NALCN,CCSER2,KCTD15,PLCB2,PLCL1,TRHDE,LRP12,RETREG2,PPP2R5E,EPDR1,BCAS3,VPS13C,LAMA1,CNTLN,PTCH1,TMEM260,STK32A,PTPRO,ZNF793,FAM184A,ENOX1,ZNF493,OXR1,RBBP8,RDX,ERI2,FIGN,SETD5,KLHDC8A,CARF,GSTCD,PCMTD2,CCDC102B,RPE,SNX22,FBXW7,ATP8B4,LRRK2,ABCA11P,ZNF568,FAM192A,CSRNP3,COPZ1,SGK1,ZFP30,CHD9,NLGN1,ANKRD6,WDR37,SLC12A2,SLC12A4,NAPB,CPEB4,OGDHL,DMRTC1,MBD5,ZSWIM8,SPP1,KDM4C,ARHGAP26,CDK19,CLASP2,TROVE2,ITPRID2,SAMSN1,ZC4H2,LARP4,NXT2,ELOVL4,DIP2A,STX1A,STXBP1,PLCB1,MMS19,TACR1,CAMTA1,ADGRL3,TBCEL,TBL1X,ATMIN,SATB2,ZEB1,RPGRIP1L,TCF12,PUM2,FAM200B,AP4E1,AKTIP,TIAM1,ACTR6,ASXL3,BHLHB9,TMPO,KAT6B,SYNPO2,TTTY15,CLHC1,SGK3,RPL7L1,EIF4ENIF1,UGT8,OSBP2,ZNF709,VGF,CCDC14,RICTOR,XRCC4,PCDH20,ZNF711,ZNF708,ZNF540,NDRG4,TCEAL7,ZNF154,REEP1,LAMP5,DHX33,ZNF225,ZXDA,STOX2,PRDM10,ADAMTS9,NAV3,PDSS2,FZD3,KAT6A,SMIM8,PHTF2,ADAMTS10,IFT88,NETO2,NETO1,FAM198A" MicroRNA hsa-miR-1259:mirSVR_lowEffct hsa-miR-1259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.94E-120 3.32E-116 3.57E-118 3.29E-117 322 1928 "ACADM,ADCY8,ADD1,BRAP,UNC5A,PWWP2A,SLC24A4,ZNF608,INTS2,PCDH19,HACE1,KIAA1324,ADGRF5,SMIM17,CEP126,PCDH10,SYT13,DPP10,LCORL,MAP4K3,USP37,PPP4R4,LINC00173,ASPA,TMEM108,ZNF582,ALDH7A1,ADGRB2,ADGRB3,MPDZ,BMPR1B,FUBP1,MTMR2,JAZF1,C5,RAB29,CACNA1B,CALB1,VXN,ISPD,RUNX1T1,SCARB1,C1orf52,LRRFIP1,MAGI1,DLGAP1,CCPG1,NUMBL,CACNA2D2,SRSF11,B4GALT6,NDST3,EPS15L1,HECTD1,MAP4K4,ARHGEF6,PCYT1B,ARMC8,AHCTF1,BAG4,CNRIP1,SLC35F1,RBM39,CRHBP,AKAP12,RNF14,ANKRD44,PHACTR3,FAM169A,DZIP3,PLCXD3,PNPLA8,PUM1,RIMS2,USP6NL,BOC,MYADM,ZFYVE16,LONRF1,KIAA0586,KCTD8,IP6K1,DBT,ELMSAN1,JAKMIP2,ZBTB24,HEPH,MFAP3L,DDX46,ALKBH8,PLPPR4,SNAP91,NR1D2,CDON,CPEB2,DTNA,ABCC5,E2F6,EBF1,EDIL3,EDNRA,MBNL2,COPS4,PLEKHA1,PAN3,EPHB1,ETV1,DNAJC27,ADGRV1,NRN1,FAM198B,SCML2,CEP78,SLC9B2,MED12L,FGF1,POLR1B,FGF13,MEX3B,RGPD5,ATP13A4,ANKFY1,EFCAB2,PDLIM5,TPK1,MPP6,TVP23A,ZMAT1,MEGF10,HRASLS5,GABRG1,B4GALNT1,ERAP1,KIAA1841,GCNT2,MMADHC,PCDH17,TCERG1,COPS8,RAB30,TOX3,ZNF638,POLL,LUZP2,GPR37,CNTRL,GRB10,GRIA2,DIDO1,GRM8,GUCY1B1,RASSF8,FRMD5,NCKAP1L,GABARAPL2,ZDHHC15,IGF1,ZIC5,IL12A,LRRTM1,SLC35G1,KCNN2,KIF2A,KIF5A,KIT,CYP27C1,LIG4,NCOA7,PACRG,MAP2,MARK1,CHIC1,TM6SF1,LRP1B,SHC3,KITLG,SAMD5,MSR1,LAYN,MYO9A,NCAM2,NEFM,NF1,CNOT4,NOVA1,DNHD1,NPR2,NPTX2,OXTR,GLIPR1L2,CNTN3,PCDH8,PDE1C,PDE4D,PFKFB2,NLGN3,PIK3R1,XRN1,FAM216A,PLCB2,MTRF1L,PURG,PMP22,LRP12,PSAT1,SDK2,DRAM2,PPP2R5E,PPP3CA,PRKAB2,RASGEF1B,MAPK9,FITM2,GRAMD1C,PTCH1,MTMR10,PTPRB,PTPRN2,FAT4,RAP1GDS1,ZDHHC14,ERI2,RFX3,PRIMA1,KLHL11,PBRM1,CCDC82,ROBO1,ROBO2,RPE,FBXW7,SPIN3,ZC3H14,PTGR2,HUNK,RMI1,SALL1,ATXN7,FERMT1,DZIP1,ST8SIA1,FAM81A,SLC8A1,CCDC88A,NAPB,SLC22A4,EPC1,MAST1,CABCOCO1,LMBRD1,FAM126B,DOP1A,SP4,MYCBP2,KDM4C,MCF2L2,TROVE2,ITPRID2,ZNF302,SSTR1,SEPT8,STXBP1,PRRC2C,NUDT10,SYT1,ANKRD28,ANKRD12,PJA1,CAMTA1,KLHL4,DMXL2,RPGRIP1L,CLASP1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,TEK,DICER1,DICER1-AS1,AP4E1,TLR4,NPL,PPIL6,ANKRD20A2,SSBP2,ZNF610,EIF4ENIF1,UBE2H,FLRT2,CCDC14,WIPF1,RICTOR,XPO1,XRCC4,PCDH20,MICU3,ZNF28,MKRN3,LYPD6,CELF4,ZNF142,TMEM237,ZNF184,SPIRE1,MAP3K12,EMSY,STOX2,HPS4,RTN4,PHTF2,CASC15,ADAMTSL3,MSRB3,FXR1,FRMD6,CPNE4" MicroRNA hsa-miR-516b*:mirSVR_lowEffct hsa-miR-516b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.00E-120 3.36E-116 3.57E-118 3.29E-117 323 1940 "ASIC1,NCKAP5,SYS1,ACTN1,KDM5D,TMEM132B,PLEKHH1,ADORA2A,PTCHD1,MTUS1,RTL9,USP35,ABCD2,ARHGAP20,SYT13,CDC42BPA,DDO,TNRC6C,SEMA4G,PDE8B,MARCH3,PCDHGB4,NUMB,ATP1B3,N4BP2L1,ADGRB3,GPR146,CFLAR,AP1M1,CACNA1G,GPC2,LDLRAD4,CACNB4,CALM1,PTBP2,CAMK2B,SPAG9,P2RX6,LRRFIP1,EVI5L,NUMBL,MS4A7,CNOT8,EPS15L1,RAB33A,CNGA3,AKAP7,IQCK,COL4A5,SUMF2,AKAP5,TBPL1,BAG4,ZNF521,RNF14,NCOR1,GDA,CS,CSF1,CSF1R,CSF2RA,OSBPL3,PDE4DIP,PLXNA4,KIAA0040,APPL1,UBXN2A,RUBCN,RIPOR2,DCAF8,TBC1D5,IP6K1,PABPC5,PITPNC1,ELMO1,KLHL3,ZC3H11A,DDX46,RHOBTB1,SEC16A,CHRDL1,DLX1,GRIN3A,RAB39B,HS3ST2,SLC12A6,PDCD6IP,DTNB,ABCC5,GOLT1B,SNX29,EDN1,EDN3,HIPK3,TMTC1,KMT5B,COPS4,TNK2,C3orf18,CALCRL,TUBD1,COQ7,SRRM1,DENND4A,ETV1,RASL12,F8,CLVS1,FAM198B,TMEM132C,DLC1,FCGR1A,FKTN,ZNF589,SLC9B2,FGF12,FGF14,TMEM164,SUCO,SYNCRIP,FLT1,SPECC1,UFM1,PDLIM5,STAMBP,TPK1,CGREF1,CSPG5,DOT1L,ABLIM2,OGA,FYB1,MEGF11,GABBR1,GHDC,TMEM8B,C15orf41,DISC1,LRRC37A6P,KIAA1841,SULT1C4,TXNL4A,COPS8,TNRC6A,STARD3,GNAO1,GPR37,DIDO1,MAN1B1,HLF,HMGCR,SMAP1,EID2B,GAREM2,IL6ST,SLC35G1,KCNN3,CREG2,KIF5A,KIFC3,KPNA5,ASPRV1,GPR155,MAN2A2,MBD1,CHIC1,MEF2C,SCAMP5,MOV10,MPP2,SAMD5,ADAM22,PTOV1,MX1,MYO5A,ZNF862,NACA,NBL1,NPTX1,PCDHGC3,PCDH8,PCDH9,PDE4A,GPR85,GNG2,PFKFB3,OLA1,SNX10,FAM216A,PLCD1,ZNF426,PRIMPOL,PNMA3,POU6F1,PPP2R2C,RASGEF1B,PRKCB,EPDR1,GRAMD1C,MASP1,VPS13C,WBP1L,GDPD2,PTCH1,BDNF-AS,MTMR10,PTK2,PTN,PTPRD,TUG1,PPP2R3C,PID1,SH3TC2,ZNF493,RASGRF2,KHDRBS2,UBR7,RIC8B,SETD5,ALG9,CARF,GSTCD,CCDC102B,NEK11,ATAT1,ATXN2,ATXN7,FNIP1,GALNT10,FAM102A,BTBD3,KANSL3,SEPHS1,SLC8A1,ARHGEF40,CDK5RAP3,SLC12A2,SLC22A4,COA1,RCOR3,IFT122,ANKRD36,SNCA,MBD5,SNRPN,DOP1A,HECW1,ZC3H13,SPART,THSD1,ZSCAN29,STAC2,ADHFE1,PHLDB1,SEPT3,SUPT5H,SYNE2,VPS13A,ADAMTS17,PLCB1,SYPL1,DNMBP,TCF4,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,USP32P1,TNS2,SIK3,CYB561A3,ZFPM2,AP4E1,ZNF106,SLC44A1,GALNT17,ACTR6,TPM1,RGMB,METTL3,ELP5,TRO,TSN,CA14,UBE2H,UBE3A,OSBP2,ZNF709,WIPF1,LAT2,WRN,XPO1,ZIC1,CADM2,LINC02210,STOX2,TUBA1A,ADAMTS9,HPS4,NAV3,URM1,FIP1L1,FAM47E,RGS7BP,FAM13C,DOCK8,ST7,UBE3B,MSRB3,IFT88,SOCS4,GAN,SRGAP2B,LAS1L" MicroRNA hsa-miR-516a-3p:mirSVR_lowEffct hsa-miR-516a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.00E-120 3.36E-116 3.57E-118 3.29E-117 323 1940 "ASIC1,NCKAP5,SYS1,ACTN1,KDM5D,TMEM132B,PLEKHH1,ADORA2A,PTCHD1,MTUS1,RTL9,USP35,ABCD2,ARHGAP20,SYT13,CDC42BPA,DDO,TNRC6C,SEMA4G,PDE8B,MARCH3,PCDHGB4,NUMB,ATP1B3,N4BP2L1,ADGRB3,GPR146,CFLAR,AP1M1,CACNA1G,GPC2,LDLRAD4,CACNB4,CALM1,PTBP2,CAMK2B,SPAG9,P2RX6,LRRFIP1,EVI5L,NUMBL,MS4A7,CNOT8,EPS15L1,RAB33A,CNGA3,AKAP7,IQCK,COL4A5,SUMF2,AKAP5,TBPL1,BAG4,ZNF521,RNF14,NCOR1,GDA,CS,CSF1,CSF1R,CSF2RA,OSBPL3,PDE4DIP,PLXNA4,KIAA0040,APPL1,UBXN2A,RUBCN,RIPOR2,DCAF8,TBC1D5,IP6K1,PABPC5,PITPNC1,ELMO1,KLHL3,ZC3H11A,DDX46,RHOBTB1,SEC16A,CHRDL1,DLX1,GRIN3A,RAB39B,HS3ST2,SLC12A6,PDCD6IP,DTNB,ABCC5,GOLT1B,SNX29,EDN1,EDN3,HIPK3,TMTC1,KMT5B,COPS4,TNK2,C3orf18,CALCRL,TUBD1,COQ7,SRRM1,DENND4A,ETV1,RASL12,F8,CLVS1,FAM198B,TMEM132C,DLC1,FCGR1A,FKTN,ZNF589,SLC9B2,FGF12,FGF14,TMEM164,SUCO,SYNCRIP,FLT1,SPECC1,UFM1,PDLIM5,STAMBP,TPK1,CGREF1,CSPG5,DOT1L,ABLIM2,OGA,FYB1,MEGF11,GABBR1,GHDC,TMEM8B,C15orf41,DISC1,LRRC37A6P,KIAA1841,SULT1C4,TXNL4A,COPS8,TNRC6A,STARD3,GNAO1,GPR37,DIDO1,MAN1B1,HLF,HMGCR,SMAP1,EID2B,GAREM2,IL6ST,SLC35G1,KCNN3,CREG2,KIF5A,KIFC3,KPNA5,ASPRV1,GPR155,MAN2A2,MBD1,CHIC1,MEF2C,SCAMP5,MOV10,MPP2,SAMD5,ADAM22,PTOV1,MX1,MYO5A,ZNF862,NACA,NBL1,NPTX1,PCDHGC3,PCDH8,PCDH9,PDE4A,GPR85,GNG2,PFKFB3,OLA1,SNX10,FAM216A,PLCD1,ZNF426,PRIMPOL,PNMA3,POU6F1,PPP2R2C,RASGEF1B,PRKCB,EPDR1,GRAMD1C,MASP1,VPS13C,WBP1L,GDPD2,PTCH1,BDNF-AS,MTMR10,PTK2,PTN,PTPRD,TUG1,PPP2R3C,PID1,SH3TC2,ZNF493,RASGRF2,KHDRBS2,UBR7,RIC8B,SETD5,ALG9,CARF,GSTCD,CCDC102B,NEK11,ATAT1,ATXN2,ATXN7,FNIP1,GALNT10,FAM102A,BTBD3,KANSL3,SEPHS1,SLC8A1,ARHGEF40,CDK5RAP3,SLC12A2,SLC22A4,COA1,RCOR3,IFT122,ANKRD36,SNCA,MBD5,SNRPN,DOP1A,HECW1,ZC3H13,SPART,THSD1,ZSCAN29,STAC2,ADHFE1,PHLDB1,SEPT3,SUPT5H,SYNE2,VPS13A,ADAMTS17,PLCB1,SYPL1,DNMBP,TCF4,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,USP32P1,TNS2,SIK3,CYB561A3,ZFPM2,AP4E1,ZNF106,SLC44A1,GALNT17,ACTR6,TPM1,RGMB,METTL3,ELP5,TRO,TSN,CA14,UBE2H,UBE3A,OSBP2,ZNF709,WIPF1,LAT2,WRN,XPO1,ZIC1,CADM2,LINC02210,STOX2,TUBA1A,ADAMTS9,HPS4,NAV3,URM1,FIP1L1,FAM47E,RGS7BP,FAM13C,DOCK8,ST7,UBE3B,MSRB3,IFT88,SOCS4,GAN,SRGAP2B,LAS1L" MicroRNA hsa-miR-3126-5p:mirSVR_lowEffct hsa-miR-3126-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-119 6.53E-116 6.87E-118 6.33E-117 302 1699 "KCNH8,ACADM,KDM5D,GALNT16,ADCY6,ADD1,ADD2,AXIN2,ADORA1,PCDH19,TBC1D14,C1QTNF1,ADGRF5,FAM135A,ZNF687,DOC2A,AMPD3,LRFN1,LCORL,PHYHD1,SEMA4G,MADD,ARHGDIA,MARCH3,EIF4G3,STX16,ZNF583,SLC2A11,ATP6V1G2,ADAM23,CARMIL3,AZGP1,MPDZ,KSR1,DST,CALB1,CALB2,CAMK2A,CAMK2G,VXN,CAST,RUNX1T1,MTMR7,SCARB1,SYNGR3,LRBA,ZMYM4,LARGE1,CRLF1,CACNA2D2,LHX2,LY86,IGLON5,CNN3,SUMF2,COL11A2,SLC4A8,ZFP28,IGDCC3,CNRIP1,CLOCK,PREPL,RBM39,CRMP1,HINFP,GDA,CS,CSF1R,ARHGEF10,CSNK1E,OSBPL3,SUSD5,VCAN,RASGEF1C,ERC2,DCAF4,BOC,ARHGAP24,ZFYVE16,TM9SF4,IST1,DGKG,SPOCK2,DNAL1,ARMCX4,ALKBH8,POM121,SGSM2,CHRDL1,EXOG,DNM1,DNAH9,DMTF1,DPP6,ECM2,DNAJB6,ANKRD46,SUGP2,APH1A,EGFR,MRO,MBNL2,IRAK4,C3orf18,CALCRL,CEP85L,MRPL37,RASL12,CLVS1,ABCA8,PTK2B,FKTN,KAT8,MED12L,OLFM1,FGF12,FGF13,TMEM164,AMOTL2,FHL1,SEMA4D,FLNC,FLT1,ANKFY1,EFCAB2,SPECC1,PRELID3A,ABLIM2,CHL1,GABRG2,ZNF234,ZNF274,ERAP1,TMEM8B,DISC1,GFRA2,POLL,GNAL,GNAO1,ZNF782,WDFY3-AS2,GPD1,TDRKH,TMEM121B,ADAMTS13,GRIN2D,ZNF496,CLASRP,KAT7,AP4S1,FAM107A,ADAMTS6,RASSF8,ZHX1,HNMT,CELF5,FAM95B1,LRRC25,ZNF678,INSM1,NME9,KCNN2,TTYH2,STMN1,SFXN5,MAN2A2,ZFYVE27,AQP11,TM6SF1,KCTD6,SCAMP5,MPP2,DBNL,SAMD5,MSI1,ADAM22,MYO9A,FXYD7,CCDC13,DNHD1,SETD4,OCRL,LOC100128398,PALM,CNTN3,DPY19L2P2,PDCD2,PDE4A,TMIE,PIK3R1,PLCB2,SLC25A23,MTRF1L,MAPKAP1,EPB41L4B,PPP1R1A,PPP2R5E,VSTM2L,MAPK10,CNNM2,CYBC1,CNTLN,NCR3LG1,ZSCAN32,PTPRB,CASTOR1,PTPRN,RAD51D,ZCWPW1,ZNF493,RASGRF1,ZDHHC14,TRIM68,RGS3,RGS4,KIF7,KIRREL1,YY1AP1,PCMTD2,CCDC102B,RPL15,SGSM1,TCP11L1,MEG3,HUNK,HSD11B1L,ATAT1,ZNF331,CCDC112,TNFRSF19,SEC14L1,COPZ1,SCAF8,SGK1,PPM1E,FERMT1,KIF16B,R3HDM2,NLGN1,SLA,LIMS2,SLC11A1,ELMO2,TET1,EPC1,INTS9,ANKRD36,KIF13A,SNRPN,TMCC1,KDM3A,HECW1,KDM4C,PEG10,SPART,NFASC,ITPRID2,SST,SSTR1,ZC4H2,ZSCAN29,STAC2,STX1A,STXBP1,ADAMTS17,PLCB1,SYN2,SLC37A2,ADGRL3,TBCEL,SMG6,TCF4,DOCK9,PHF24,OBSL1,USP32P1,FRYL,HIF3A,KHDC1,THRA,CSMD1,TNS1,ZNF346,SYNPO2,RUSC1,UBE3A,UBTF,VGF,VLDLR,LMF1,KLC2,LGI4,MKRN3,POLR3H,SLC30A4,MAP3K12,KCNAB1,WNK3,UBE3B,CASC15,FAM219B,DPF3" MicroRNA hsa-miR-875-3p:mirSVR_highEffct hsa-miR-875-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-119 7.79E-116 8.12E-118 7.47E-117 314 1839 "KCNH8,ACADM,CLK4,XKR4,ADCY6,CCDC85A,ADD1,ADORA2A,AP2A2,MTUS1,HACE1,TBC1D14,WDR35,TXNDC16,SPARCL1,SEMA6A,SPOP,MARCH4,OGT,DPP10,ANK2,PHF12,PKP4,PARG,APBA2,UPRT,VAT1L,BCAS1,LGR5,IGDCC4,MARCH3,NCOA1,STX16,RNF182,DPY19L3,RGS9,NRP2,GPR146,ARHGEF7,NAE1,BTK,IL33,CA8,KALRN,SLC25A14,CAST,ISPD,SPAG9,RUNX1T1,CBR1,MTMR7,ZMYM4,LRRFIP1,NUMBL,CFL2,CHN1,NDST3,TPP1,STOML1,C4orf33,TMEM184B,HECTD1,ARMC8,AKAP6,SLC4A8,RCHY1,MYRIP,IGDCC3,CNRIP1,SLC35F1,CRMP1,GDA,SNCAIP,CSNK1G3,VCAN,CNTNAP2,FAM169A,PHF14,PNPLA8,CTH,PUM1,ZSCAN23,CYBB,ARHGAP24,ZNF337,DGKB,DAPK1,GIT2,SPATA2,ELMO1,GRIN3A,USP3,DNM1L,AASDH,EDNRB,HIPK3,CNNM1,SEMA3D,YAF2,APH1A,MRO,MBNL2,GOLGA7,KCTD3,TMEM35A,RCAN2,RASGRP2,EPHB1,ENPP6,STX2,SRRM1,NCALD,MRPL37,ZNF461,SH3YL1,TAOK3,SEC24B,FGF12,SCARA3,IP6K2,SYNCRIP,ATP13A4,NBEA,SPECC1,ZNF605,KHDRBS3,FYN,HRASLS5,GABRB3,GABRG2,GAD1,GALC,RAPGEF6,TMEM8B,MTHFD2,DISC1,LRRC37A6P,NEU3,GCNT2,SRCAP,MSTN,CRCP,COPS8,SPIN1,RAB30,CBX1,GPD1,GPR12,AP4S1,PSIP1,IRAK3,FRMD5,ELOVL5,HSPA1L,IRF8,IL6R,IL6ST,ITGAM,KCND2,STXBP5,SYTL4,NCOA7,LSS,PIK3AP1,MARK3,MAT2A,PPM1L,XRRA1,MMP16,MSI1,MYO7A,NF1,NOVA1,NUCB2,IGSF11,OPA1,P2RY1,GPR137C,PCSK5,PDE4D,GNG2,PFKFB2,SERPINI1,SNX10,SMIM7,TRHDE,MAPKAP1,EXOSC10,ING3,MBOAT7,PPP2R5E,RANBP3L,CEP41,GRAMD1C,HYDIN,GDPD1,VPS13C,CNTLN,SPDL1,ZIK1,PTPRD,C1orf109,ZSCAN2,ACSS3,FAM66C,GTDC1,RFX3,SLC25A36,NUDT11,EXD2,CARF,GSTCD,ELP2,RPE,NEK11,RPL15,ATP8B4,RPS6KA2,MAP6D1,KCNIP1,CLIP1,ZNF568,TRAPPC13,SEMA6D,ATXN7,SCN2B,PRCD,SCP2,TNFRSF19,MRAS,KIF27,SH3BGR,KIF21A,PPM1E,NLGN1,ANKRD6,NUBPL,FAM81A,SLC2A5,SEPHS1,CCDC88A,SLC11A1,CPEB4,ZNF667,GKAP1,CDK5RAP2,SMARCD3,LIMCH1,SNAP25,KIF13A,LMBRD1,KDM4B,FAM219A,BDP1,FNBP1,KDM4C,LMO3,CLASP2,NKAIN2,ERBIN,STAU1,ELOVL4,CEP68,RGL1,DIP2A,KLHL7,PRRC2C,DNAJC9,SYN2,SYT1,COBL,ADGRL3,DMXL2,TPCN2,SYNE1,FRYL,PMS2CL,DICER1,C18orf54,GPR161,ZMAT3,TIAM1,ERCC6L2,TMPO,ZKSCAN5,SGK3,UBE3A,GORASP1,UGT8,OSBP2,USP1,CCDC14,P2RY12,CFAP298,ZBTB14,ZIC1,ZNF74,NDRG4,ZFAND5,SMARCAD1,DHX33,SLC30A4,EMSY,DNALI1,SLC38A1,RNF103,ADAMTS9,MPPE1,EPM2A,KAT6A,PHTF2,CASC15,FXR1,GAN" MicroRNA hsa-miR-3128:mirSVR_lowEffct hsa-miR-3128:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-119 1.01E-115 1.04E-117 9.55E-117 317 1876 "DGCR6,KCNH8,SYN3,CLK4,KDM5D,NDRG3,ADCY6,ADD2,PWWP2A,DPY19L2P4,ZNF608,INTS2,HECW2,OSBPL6,TAOK1,ADGRF5,LTBP4,OGT,CCDC146,PPFIA4,APBA2,APC,CASK,CCAR2,CHID1,EIF4G3,ATP2B2,ADAM15,LINC00847,BCHE,DNAJC27-AS1,ARHGEF7,MTMR3,CA12,CACNB4,CALB1,THSD7A,PTBP2,CAMK2A,VXN,SPAG9,LRBA,ARHGEF2,SEPT7,ZBED1,CCPG1,CRLF1,UBE2L6,NUMBL,ASIC3,CHN2,B4GALT6,NRXN3,FAM189A2,CNN3,CNR1,SUMF2,LETMD1,COX4I1,BAG4,CLOCK,TRIM69,SUSD5,CNTNAP2,PLXNA4,KIAA0040,PHF14,GPSM1,CYBB,MYADM,RIPOR2,ARHGAP24,EARS2,TBC1D5,ARMCX2,YTHDC1,DGCR5,ZBTB24,ELMO1,ALKBH8,RHOBTB1,PLPPR4,SV2B,SPOCK3,SGSM2,DYNC1I1,NR1D2,ECM2,FAM78B,MAMLD1,KRBA2,E2F6,EDN1,EDNRA,TMTC1,YAF2,PHF20L1,EGFR,EGR3,EIF4G2,RGS17,CALCRL,PAN3,DCTN4,USPL1,EPB41L2,RASGRP2,DENND4A,ZNF549,RASL12,ADGRV1,NRN1,FAM198B,TAOK3,DLC1,ZSCAN30,FGF12,AMOTL2,HPCAL4,SYNCRIP,SLC37A3,NBEA,FAM49B,TRIM16,ATP6V1H,KHDRBS3,CELF1,CGREF1,ERAP1,C15orf41,DISC1,FREM1,PCDH17,GLI2,TOX3,MSL3,ZNF638,KDM2B,HTATSF1,FERMT2,GPD1,GPD2,PRUNE2,GPR34,ADAMTS13,PRDM5,LINC01089,PADI2,HMGCR,HNMT,AGFG1,LRRC75A,IRF8,IGF1,SCIN,INPP5B,SLC6A17,SLC35G1,KCNN2,LAMP2,LIFR,SMAD1,ZFYVE27,MAP2,MAP6,MATN3,MBD1,MBNL1,LRP1B,SAMD5,MSR1,MYO6,MYO9A,NCAM2,NEK1,NF1,NTRK2,IGSF11,CHAMP1,CLDN11,DPY19L2P2,PCDH8,PDE1C,ENPP2,GPR85,CYTL1,OLA1,PIK3C2A,RETREG2,PPARA,PPM1B,PPP2R5E,RANBP3L,MAPK7,DIRAS2,WBP1L,PIGG,CNTLN,PTK2,EML5,TMEM145,ZNF615,TUG1,RASGRF1,RBBP6,MSANTD2,RDX,RET,REV3L,ERI2,GTDC1,RGS12,RNH1,LGI2,TMLHE,GSTCD,ROBO2,SPIN3,PTGR2,MEG3,NCBP3,TRAPPC13,RMI1,DGLUCY,SEMA6D,LRFN5,TNFRSF19,GALNT10,SCAF8,ASAP3,SHC4,HKDC1,ST6GAL1,CNKSR2,DZIP1,FAM81A,PPP4R3A,FAM214B,KANSL3,BTBD7,DMRTC1,IFT122,MBD5,SNRPN,TMCC1,FAM126B,PDZRN3,MYO16,PDZD2,TRERF1,BDP1,ZSWIM8,SPTAN1,SPART,POGZ,ZNF302,SAMSN1,SSTR1,NKAIN2,SEPT8,TTBK2,KANK1,RHBDL3,ASTN2,TACC1,TACR1,TAL1,ADGRL3,DMXL2,TCF12,SYNE1,DOCK9,PHF24,GPRIN3,SIK3,CYB561A3,RNF216P1,SIRT1,ZFPM2,AKTIP,ARL10,MTMR14,BHLHB9,ERCC6L2,CSMD1,NR2C2,SYNPO2,TRIO,NEIL2,TSN,TUBB1,PLPPR2,XRCC4,ZNF708,TRIM9,MKRN3,SPHK2,TCEAL7,ZNF154,REEP1,ANKS1B,SMARCAD1,PRDM8,KCNAB1,TRIM16L,DOCK8,RTN4,UBE3B,HNRNPA3,ACTR3B,FAM219B,TRAM2-AS1,TIGD6,SNX14,FXR1,GAN,JPH3" MicroRNA hsa-miR-3175:mirSVR_lowEffct hsa-miR-3175:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-119 1.06E-115 1.08E-117 9.96E-117 314 1841 "ABCF1,ASIC1,SYS1,TMCC3,GALNT13,ADD1,BRAP,KIAA1211,PTCHD1,SLC24A4,MTUS1,KIAA1324,WDR35,CC2D2A,CARNS1,PCDH10,DOC2A,PITPNM2,PHF12,PHYHD1,VAT1L,BCAS1,PRX,SPTBN4,ZFYVE28,ARHGDIA,ARHGDIG,ARRB2,CDK13,MARK4,TMEM108,ATP1A3,EIF4G3,ATP2B2,ATP6V0A1,ADGRB2,BCL7A,NRP2,CFLAR,BMPR1B,MYRF,DDR1,CACNB4,LURAP1,CABP7,CAMK2A,CAMK2B,PRC1,CBFA2T2,LRBA,ARHGEF2,EVI5L,LOC730101,TIGD7,NUMBL,PLEKHB1,NDST3,LHX2,NRXN3,STOML1,IQCK,AKAP6,GAL3ST1,SMARCAL1,ZNF385A,SEC31B,CLOCK,C2CD2,CREM,RBM39,CRMP1,NCOR1,CLIP3,CS,CSF1,CSF1R,RIMS4,PDE4DIP,KIAA0040,USP6NL,ARHGAP32,DCAF8,TM9SF4,TBC1D5,MAML1,AIF1L,DNAL1,KIAA0753,WDR20,SEC16A,GRIN3A,RPS6KL1,SHANK1,DPP6,ACOT8,ABCC5,EDN3,EDNRB,OPTN,CELSR3,EGFR,MRO,EGR3,ING4,CERCAM,ELN,C3orf18,USPL1,SPEG,ETV1,MRVI1,FCGRT,FKTN,STRADA,FGF11,TMEM164,UBE2E3,AGAP2,SEMA4D,ANKFY1,DCTN2,APOPT1,PDLIM5,CAMKK2,ATP2C1,BRSK1,GABBR1,GAD1,GHDC,SIGLEC8,INPP5K,KIAA1841,ALDH1L1,GCNT2,GPR162,CYP46A1,MMADHC,GGT7,RUNDC3A,POLL,WDFY3-AS2,PRRC2B,GPD2,PRUNE2,TDRKH,PCLO,DIDO1,C1QL4,ADAMTS13,ZNF496,CIT,FAM107A,FAM222A,MUM1,PADI2,SYNPO,AGBL5,CELF5,MSL1,KIAA1755,DISP2,IL6R,SLC6A17,METTL21A,KCND1,KCNN1,KHK,A1BG-AS1,NCOA7,LSS,ASPRV1,ZFYVE27,MAP4,SCAMP5,MSI1,MSR1,PTOV1,TAGLN3,MX1,MYO7A,MYO9A,RTL5,ZNF862,NBL1,CCDC13,NF1,NFE2L2,ALDH1L2,NFYA,CNOT4,SMIM11A,ZNF827,PDE4A,TMIE,CCSER2,FAM216A,PLIN1,MTRF1L,ING3,SEPT4,EPB41L4B,PILRA,FA2H,POLR2F,FSD1,PPARA,PPP5C,MAPK3,EPDR1,MAPK9,PRPSAP2,MASP1,CYBC1,CNTLN,PTPRE,PTPRO,SLC25A48,FAM66C,IQSEC3,PRIMA1,PBRM1,PNMA8A,KIRREL1,EPHA10,ZNF671,ATP8B4,GLDN,SGSM1,STK32B,ATAT1,FAM192A,ATXN7,SEC14L1,CASC3,FOXRED1,COPZ1,PUF60,SH3BGR,KIF16B,MYO18A,AMBRA1,FNDC3A,ABLIM3,SLC6A8,RADIL,CCDC88A,SLC9A5,SMARCC2,CDK5RAP2,RCOR3,INAVA,KDM4B,DOP1A,TRERF1,MYCBP2,ARHGAP26,IQSEC2,ZBTB43,DDN,ITPRID2,SSTR2,NKAIN2,STAC2,PHLDB1,ARHGEF9,SYP,TACC1,EXOC7,TAL1,AGTPBP1,SMG6,KLHL4,MGRN1,SIN3B,NAT16,FAM189A1,NSD1,TNS2,ARHGAP9,HIF3A,KHDC1,C18orf54,ICAM5,TLR4,RIMBP2,PIK3R5,NPL,WBP2,ZNF346,SMUG1,STXBP4,TRPM2,KCNE5,TSC1,TTTY15,FAM155A,GORASP1,FLRT2,PLEKHH2,BCL2L13,MTCH1,PLPPR2,TOM1L2,ZNF19,CELF4,REEP1,TMEM198,MEIS3,EMSY,GDPD5,PRDM10,PDSS2,HNRNPA3,TMEM63C" MicroRNA hsa-miR-338-3p:mirSVR_lowEffct hsa-miR-338-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-119 1.45E-115 1.46E-117 1.35E-116 320 1914 "KCNH8,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,PLEKHH1,USP31,UNC5A,ADRB2,AP2A2,KLHL13,OSBPL1A,SMIM17,SEMA6A,ALCAM,SRPX,MARCH4,GPRASP2,PDZD4,AMPD2,AMPD3,SUGT1P4-STRA6LP-CCDC180,APBA2,APC,LGR5,SFMBT2,IGDCC4,ZFYVE28,ARNTL,RGS20,LINC00173,CDK13,NUMB,SLC2A11,N4BP2L1,DPY19L3,DOCK11,BBS2,RGS9,KSR1,GYG2,CFAP410,CACNA2D1,CACNB4,PTBP2,VXN,CH25H,RUNX1T1,KRIT1,USP6,CD86,L3MBTL4,NUMBL,SRSF11,ASIC3,CHRNA4,B4GALT6,SULT4A1,HECTD1,CNR1,FAM149A,ABI3BP,TBPL1,COX4I1,CRMP1,NCOR1,GDA,CRYM,PDE4DIP,CNTNAP2,DZIP3,PPP1R16B,KIAA0040,PPP6R2,FAM131B,BOC,KATNAL2,ZFYVE16,LONRF1,DAPK1,AIF1L,SPATA2,ELMO1,TIAM2,RUSC2,DDX46,RHOBTB1,PLPPR4,SPOCK3,GRIN3A,HS3ST2,DMTF1,TOM1,ABCC5,DNM1L,HEYL,SEMA3D,TMTC1,FRY,USPL1,ENO2,RCAN2,LRRC17,STX2,ERBB2,FAM198B,CEP78,FKTN,FER,AMOTL2,PRKAG2,UBE2E3,IP6K2,SYNCRIP,NELFCD,CAMKK2,CELF1,CGREF1,NSG1,MSANTD4,HHIPL1,FYB1,GABRG2,ZNF274,C15orf41,LRRC37A6P,NFU1,PPARGC1A,ZNF276,TCERG1,COPS8,GNG4,FERMT2,WDFY3-AS2,ADGRA3,PRUNE2,PCLO,PLCD4,GRM8,RNF165,COQ10A,BVES,ZHX1,GABARAPL2,HMGCR,ZDHHC15,NEGR1,SHISA6,SMAP1,ICA1,IRF8,GAREM2,RBPJ,TJAP1,INPP5B,NME9,KCNB1,KCNH2,KCNJ16,KCNK3,KIT,IPO5,CYP27C1,STMN1,LMO2,GPR155,MAP2,MAP6,AQP11,CHIC1,LRP1B,MEIS1,MEIS2,MID1,PPM1L,COL28A1,MSR1,N6AMT1,LYRM9,MYO7A,ZC3H12B,NEFH,NFE2L2,NFYA,NINJ2,NRCAM,SMIM11A,NTRK2,NUCB2,TBC1D25,OXTR,PCSK1,PCSK5,PDCD2,PRTG,PDE1C,ENPP2,SLC10A4,PFKFB2,OLA1,XRN1,PKM,PURG,PRIMPOL,LRP12,EXOSC10,MAGEL2,EPB41L4B,PPP1R1A,PKIA,PRKCB,EPDR1,SLC26A11,PRPH,GDPD1,MASP1,SNRK,CNTLN,ANKHD1,TMEM260,ZSCAN32,PTPN13,PTPRE,PTPRO,TMEM145,NKAIN1,TTC13,PPP2R3C,TMEM255A,SH3TC2,FAT4,SUSD4,KHDRBS2,TRIM68,RET,REV3L,RGS12,MRPS18A,RNASEL,ZNF532,SETD5,MRAP2,GLDN,ADAL,LRRK2,ZNF568,DGLUCY,SALL1,SEMA6D,SCN8A,PRCD,SCP2,MRAS,KIF21A,PPM1E,FBXO11,R3HDM2,SLC8A1,SIRT2,CCDC88A,SLC9A5,TET1,GKAP1,DMRTC1,KIF13A,SOX11,NMNAT2,MYCBP2,KDM4C,ZC3H13,ZBTB43,NFASC,SSTR1,NKAIN2,CEP68,DIP2A,ARHGEF9,ASTN2,CAMTA1,WSCD1,SATB2,CLASP1,SYNE1,DOCK9,RNF216P1,ZFPM2,AP4E1,AKTIP,TIAM1,MTMR14,ACTR6,R3HDM1,C9orf85,RGMB,KCNE5,TSN,TSC1,CLHC1,RPRM,GORASP1,UGT8,ZNF709,TBC1D15,GUSBP1,XPO1,LGI4,ZNF28,SPHK2,LAMP5,ZFAND5,SLC38A1,PRDM10,RNF103,PPP1R3F,KCNAB1,UBE3B,FBXO36,FXR1,LAS1L" MicroRNA hsa-miR-376c:mirSVR_lowEffct hsa-miR-376c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.09E-119 1.73E-115 1.73E-117 1.59E-116 302 1705 "ASIC1,TMEM132B,ADCY6,SLC24A4,ZNF608,CASKIN1,OSBPL1A,OSBPL8,CC2D2A,HFM1,PCDH10,AMPH,APC,UPRT,FAM131A,PPFIA3,USP37,PPP4R4,CASK,MARK4,RASL11B,TMEM108,SLC4A4,ATP1B3,ATP2A2,TTLL9,BACH1,BARD1,BCL7A,DST,FUBP1,IL33,LDLRAD4,CACNB4,ISPD,RUNX1T1,ZNF501,CCNH,SLC16A4,CDH2,DCLK1,LRRFIP1,CDO1,FOXN3,CHN1,CNOT8,LHX2,RAB28,NRXN3,FBXO7,SRP14-AS1,HECTD1,CNN3,ABI3BP,MYRIP,ZFP28,SLC35F1,C2CD2,RBM39,AKAP12,HAPLN1,ANKRD44,CLIP3,SLITRK5,DZIP3,APPL1,RIMS2,USP6NL,KIAA0408,ARHGAP32,ZFYVE16,LONRF1,KIAA0586,DGKB,DAPK1,ELMSAN1,ZNF804A,ZBTB24,WDR20,ZNF582-AS1,GRIN3A,DMD,NR1D2,ECM2,ABCC5,EDNRA,TMTC1,CELSR3,MBNL2,KMT5B,PLEKHA1,RGS17,CALCRL,PAN3,DCTN4,EPB41L2,RABEPK,SRRM1,NCALD,VPS26C,EXTL2,KATNAL1,ZNF461,FCGR1A,CEP78,FKTN,FECH,SEC24B,FGF12,POLK,MEX3B,SYNCRIP,FLT1,ANKFY1,TRIM16,ATP2C1,KHDRBS3,CELF1,ST6GALNAC3,MSANTD4,OGA,FYN,GABRG1,GALC,IQGAP2,DISC1,CPLX2,KIAA1841,IGSF5,ALDH1L1,CYP46A1,MMADHC,TCERG1,LUZP2,GNAO1,FERMT2,ADGRA3,LILRA2,GPR12,SERP2,ATE1,ZNF496,FAM19A2,ZBTB49,AP4S1,HAS2,ZHX1,PACSIN2,FRMD3,BACH2,SYNPO,AGBL5,ZDHHC15,AGFG1,EID2B,IL12A,KCNF1,CREG2,KIF5A,STXBP5,LIG4,PAXBP1,SMAD1,MAP6,LRP1B,KCTD6,MID1,MMP16,ADAM22,MYO6,MYO9A,NEXMIF,NF1,NFE2L2,ALDH1L2,SMIM11A,NTRK2,CHAMP1,OPA1,PAX6,PCDH8,PDE4B,TMOD2,OLA1,CCSER2,XRN1,GPSM2,PCDH18,PDZRN4,PMP22,STRN3,LRP12,SCHIP1,SDK2,PPARA,PPM1B,PPP2R5E,PKIA,HYDIN,RELN,VPS13C,CNTLN,PTCH1,SPDL1,PTN,PTPRB,PTPRD,PTPRG,PID1,ZNF793,FAM184A,NWD1,KHDRBS2,GAL3ST4,RET,REV3L,GTDC1,UBR7,RGS4,RIC8B,LGI2,ZNF532,ALG9,CARF,CYB561D1,CCDC25,CCDC102B,NEK11,FBXW7,LRRK2,ATAT1,CLIP1,SEMA6D,SCP2,KIF21A,PPM1E,FERMT1,ASAP3,SHC4,FBXO11,CNKSR2,ABLIM3,PPP4R3A,SMARCC2,FAM219A,DOP1A,SP4,ZC3H13,RBM26,TROVE2,ITPRID2,SAMSN1,NKAIN2,ELOVL4,ARHGEF9,VPS13A,PLCB1,SLC37A2,MCF2L,FAM208A,KLHL4,TCF4,DMXL2,ZEB1,FAM189A1,PCDHB9,SLC19A3,USP32P1,RNF216P1,PMS2CL,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,R3HDM1,DOK6,RGMB,TRIO,TRPS1,HIRA,USP1,ZNF709,TBC1D15,VSNL1,XRCC4,ZNF32,ELFN1,TMEM237,SLC30A3,CADM2,STOX2,ADAMTS9,CIAPIN1,FIP1L1,TRIM16L,EPM2A,FZD3,RTN4,SMIM8,HNRNPA3,TTC7A,FRMD6" MicroRNA hsa-let-7g:mirSVR_lowEffct hsa-let-7g:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.16E-119 4.01E-115 3.97E-117 3.65E-116 318 1897 "SYS1,GALNT16,GALNT13,PLEKHH1,UNC5A,ADRA1B,OLMALINC,AP2A2,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,CDC42BPA,ANK2,LCORL,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM15,MPDZ,CACNB4,PTBP2,CAST,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,ASIC3,MS4A7,RAB33A,TPP1,ABCG2,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,ANKRD44,GDA,TRIM69,CS,RGS6,SEC24C,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,ERC2,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,SPATA2,ZBTB24,DDX46,POM121,SNAP91,TMCC2,GRIN3A,DOCK2,DMTF1,SLC12A6,DPH1,PDCD6IP,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,CNNM1,YAF2,PHF20L1,EBI3,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,USPL1,EPB41L2,EPHB1,RABEPK,SRRM1,NCALD,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,CORO2B,DLC1,RACK1,GTF2IRD2,HPCAL4,IP6K2,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,RABL2A,LINGO1,HAS2,HLF,HMGCL,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,INPP5B,SLC35G1,CDH20,KCND1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,SFR1,NEFM,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB2,PFKFB3,ZNF655,PLCB2,TRHDE,SCHIP1,RANBP3L,PRKACB,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,ZIK1,PTPRD,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,GAL3ST4,KCTD17,DCUN1D2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,SPIN3,KIAA0895L,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,STUM,FOXRED1,HSPA4L,PPM1E,CPEB3,WDR37,SLA,BTBD3,EPN2,FAM214B,KDM4D,ATF7IP,CPEB4,MAST1,MYH15,IFT122,INAVA,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,SPTB,TSPYL2,RBM26,DDN,POGZ,SSTR2,PLCB1,SLC37A2,PDLIM2,FBXW11,RPGRIP1L,TCF12,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,AP4E1,ARL10,TK2,NPL,C9orf85,WBP2,CHST5,RGMB,SMUG1,TRIO,TRO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,ZNF709,VSNL1,WIPF1,PCDH20,ZNF708,ZNF28,MEIS3,LINC02210,SIGLEC10,NAV3,FIP1L1,TRIM16L,UBE3B,KAT6A,FBXO36,CASC15,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-3138:mirSVR_lowEffct hsa-miR-3138:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.32E-119 4.66E-115 4.56E-117 4.20E-116 318 1898 "SYN3,ASIC1,ACTN1,NDRG3,TMEM132B,PSMG3-AS1,GALNT13,ADD2,PLEKHH1,AP2A2,CASKIN1,AK2,ARHGAP20,GPRASP2,BEGAIN,AMPD2,MYH7B,PPFIA3,USP37,CDC14B,SEMA4G,MADD,IGDCC4,CASK,ARNTL,ARRB1,PLA2G4C,NCOA1,INSYN2B,TMEM108,RIPK1,ADAM23,CARMIL3,ADGRB3,LINC00847,SEC11C,RGS11,SCAPER,CASTOR3,BAIAP3,CAMK2B,CAPN3,RUNX1T1,CBR1,CBS,CLDN10,USP6,CD86,ENTPD6,C1orf52,ZMYM4,L3MBTL4,DLGAP2,CCPG1,SRSF11,ASIC3,PLEKHB1,NDST3,DGCR9,QKI,TMEM184B,SRP14-AS1,IGLON5,ARHGEF6,COL11A2,AKAP5,TBPL1,TOGARAM2,CLOCK,CDC42BPB,CREM,GDA,SNCAIP,SEC24C,OSBPL3,SOCS5,CNTNAP2,PLXNA4,FAM169A,KIAA0040,CTH,RIMS2,DCAF4,RUBCN,ARHGAP32,DCAF8,IST1,DAPK1,SCRN1,GIT2,ARMCX2,MYEF2,POM121,SPOCK3,ZNF582-AS1,DNM1,HS3ST2,SLC29A4,CDON,DPP6,DUSP9,AASDH,EDN1,EDNRB,APH1A,KMT5B,PCOLCE2,LRRC17,MTSS1L,RABEPK,MRVI1,EZH1,CHST15,FCGRT,ZNF589,GORAB,SEC24B,FER,GTF2IRD2,POLR1B,SPSB4,FGFR1,EVL,FLT1,ANKFY1,SYT3,POMT1,STAMBP,ERGIC3,MSANTD4,TPPP3,AP4B1,GALNT15,ZNF234,ZNF559,ALDH1L1,SULT1C4,GGTA1P,GGT7,ZNF276,TTBK1,COPS8,SPIN1,STARD3,CBX1,GNAL,TDRKH,GRB10,DIDO1,ADAMTS13,CIT,GSTM5,RNFT2,GUCY1A1,SLC2A6,FAM222A,UBE2QL1,ARHGAP36,MIER3,LRRC75A,IDH3B,ZNF678,LRRTM1,SLC35G1,TTYH2,NCOA7,MAN2A2,MAP2,MARK1,MAT2A,MATN3,MEIS2,KITLG,SCAMP5,PPM1L,POC1B,AFF1,XRRA1,MMP16,N6AMT1,LYRM9,MYO6,HNRNPM,SFR1,NTRK3,NUCB2,OXTR,DPY19L2P2,GNG2,TMOD2,PFKFB4,ZDHHC8,PKD1,XRN1,NLE1,FAM216A,PLCB2,PLEC,PCDH18,PURG,PNMA3,ING3,RETREG2,SEPT4,POLR2F,FSD1,PRKACB,MAPK4,MAPK9,PRODH,PTPRB,PTPRD,PTPRE,CASTOR1,NKAIN1,PID1,FAT4,NWD1,ZDHHC14,GAL3ST4,TRIM68,UBR7,MRPS18A,ARMC5,ROBO2,ELP2,EPHA10,RPL15,STK32B,MAP6D1,LRRK2,MEG3,ABCA11P,DGLUCY,SEMA6D,SCP2,COPZ1,RASA3,FERMT1,R3HDM2,ST6GAL1,DZIP1,LIMS2,PKNOX2,SLC6A8,CCDC88A,CXXC4,MAST1,RCOR3,INAVA,MAPKBP1,KIF13A,RBM34,USP33,SOX3,BDP1,NMNAT2,ARHGAP26,ZBTB43,SPART,NFASC,ITPRID2,LARP4,SSPO,STX1A,SEPT3,ADAMTS17,PLCB1,C12orf76,PJA1,PDLIM2,ALG1,TBCEL,FBXW11,KLHL4,SIN3B,USP22,SZT2,OBSL1,USP32P1,TNS2,HIF3A,DICER1-AS1,C18orf54,SLC44A1,ACTR6,KAT6B,WBP2,RGMB,SYNPO2,TRPS1,CLHC1,UCHL1,ZNF709,VIPR2,TBC1D15,GUSBP1,ZIC1,ZNF708,ZNF138,POLR3H,SPIRE1,ZNF213,SLC30A4,EMSY,MFF,NAV3,FIP1L1,ITM2C,FAM47E,UBE3B,FBXO36,CASC15,ADAMTSL3,JMJD1C,TRAM2-AS1,ST8SIA2,SPATA13" MicroRNA hsa-let-7i:mirSVR_lowEffct hsa-let-7i:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.00E-118 5.59E-115 5.43E-117 5.00E-116 322 1947 "GALNT16,GALNT13,PLEKHH1,UNC5A,OLMALINC,AP2A2,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,FAM135A,BEGAIN,CDC42BPA,ANK2,LCORL,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM15,MPDZ,CACNB4,PTBP2,CAST,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,ASIC3,MS4A7,CNOT8,TPP1,ABCG2,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,SPATA2,ZBTB24,DDX46,PLPPR4,SNAP91,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,PDCD6IP,ARRDC4,DTNA,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,CNNM1,YAF2,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,RACK1,GTF2IRD2,HPCAL4,IP6K2,FLT1,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,ZMAT1,HRASLS5,ZNF234,SIGLEC8,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,RABL2A,LINGO1,HAS2,HLF,HMGCL,ZDHHC15,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,INPP5B,SLC35G1,CDH20,KCND1,LAMP2,SYTL4,HECTD2,NCOA7,MAN2A2,MAP4,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,SFR1,NEFM,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,ZNF655,PLCB2,TRHDE,MAPKAP1,SCHIP1,RANBP3L,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,ZIK1,PTPRD,CASTOR1,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,GAL3ST4,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,SPIN3,KIAA0895L,TCP11L1,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,GALNT10,FOXRED1,MRAS,HSPA4L,CPEB3,WDR37,BTBD3,EPN2,FAM214B,KANSL3,KDM4D,ATF7IP,CPEB4,MAST1,MYH15,IFT122,INAVA,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,NMNAT2,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,DDN,POGZ,SSTR2,ST5,PLCB1,MMS19,PDLIM2,FBXW11,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,DICER1-AS1,AP4E1,ARL10,TK2,NPL,C9orf85,WBP2,CHST5,RGMB,SMUG1,TRIO,TRO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,SLC35A4,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,ZNF708,MICU3,ZNF28,ZBTB38,MEIS3,LINC02210,SIGLEC10,FIP1L1,TRIM16L,FBXO36,CASC15,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-218-2*:mirSVR_lowEffct hsa-miR-218-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-118 8.99E-115 8.64E-117 7.96E-116 307 1773 "ASIC1,SYS1,BRAP,PLEKHH1,KIAA1211,ESYT2,BEND6,SLC24A4,AGT,HACE1,OSBPL6,OSBPL8,CC2D2A,HFM1,ALCAM,ARHGAP20,DPP10,CCDC146,MAP4K3,UPRT,BCAS1,CADPS,PCDHGB4,ATP1B3,ATP2A2,ZNF583,TTLL9,RGS9,KSR1,SCAPER,IL33,CALB1,CALM1,KALRN,HAP1,CH25H,SPAG9,RUNX1T1,KRIT1,CCNH,MTMR7,CBFA2T2,ZBED1,CDH2,DLGAP1,NUMBL,FOXN3,CHN1,PLAA,PPT2,CLCN3,NGEF,ABCG2,SRP14-AS1,IGLON5,IQCK,FAM149A,LETMD1,AKAP5,MYRIP,SLC35F1,ENTPD4,RBM39,LRIG1,ARHGEF10,CSNK1E,SIPA1L1,VAC14-AS1,PDE4DIP,PLXNA4,SLITRK5,PLCXD3,PNPLA8,PUM1,USP6NL,KIAA0408,ARHGAP32,GAPVD1,ZNF337,KCTD8,SCRN1,ARMCX4,JAKMIP2,DGCR5,LYPD1,SPOCK3,MTX3,FAM107B,ZNF582-AS1,EXOG,GRIN3A,USP3,DMTF1,DPH1,CASP8AP2,PDCD6IP,RCAN1,DTNA,DNAJB6,FARSB,E2F5,EDN1,FCF1,TMTC1,PHF20L1,ELN,USPL1,MTSS1L,GPHN,ZNF549,ANKMY1,ADGRV1,MRVI1,CLVS1,NSRP1,ZNF461,SLC9B2,SUCO,PCYOX1,PSD2,C2orf88,NBEA,SMC2,SPECC1,STAMBP,CELF1,CSPG5,GAD1,RAPGEF6,KIAA1841,CPLX1,GATM,LYVE1,BRD8,SPIN1,TOX3,TNRC6A,ZNF638,CBX1,KCNMB4,PCLO,GRIN2D,RNF165,GSTM5,MUM1,FRMD5,HLF,RBPJ,IL6R,KCNJ5,CREG2,KIT,STXBP5,STMN1,MAP2,AQP11,MATN3,LRP1B,KCTD6,AFF1,AFDN,SAMD5,ADAM22,NRBP2,MXI1,MYO6,MYO9A,HNRNPM,ZC3H12B,NME4,SETD4,OCRL,CHAMP1,CLDN11,GLIPR1L2,PAX6,PCDHGC3,PCSK1,PCSK5,PDE4D,PFKFB3,ABCB1,PIK3C2A,ANKRD16,LRP12,SCHIP1,ING3,PPP2R5E,PRKACB,PKIA,PRPH,GDPD2,ZIK1,PTPRB,PTPRD,RAD51D,RAP1GDS1,ZNF493,REV3L,ERI2,GTDC1,KIF7,SLC25A36,LGI2,CCDC82,CARF,ROBO1,SPIN3,ZNF671,MCMBP,LRRK2,ABCA11P,KCNIP3,ZNF568,SCN2B,PRCD,SCP2,SMPD3,SUPT20H,PPM1E,FBXO11,CNKSR2,NLGN1,DZIP1,KANSL3,PKNOX2,SLC6A11,SLC12A2,ATF7IP,ZNF667,SMARCD3,PDZRN3,BDP1,KDM3A,ZC3H13,CDK19,SPART,POGZ,ITPRID2,SSTR2,ZSCAN29,SULF2,SEPT3,RHBDL3,SYT5,TACR1,CAMTA1,TBL1X,ZFP90,CUX2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,RNF216P1,DICER1-AS1,AP4E1,ZNF106,ARL10,MTMR14,TK2,BHLHB9,ERCC6L2,KAT6B,TPM2,ELP5,STXBP4,PPIL6,TSC1,ZKSCAN5,RPL7L1,EIF4ENIF1,UBE2H,OSBP2,USP1,TBC1D15,LAT2,ZBTB14,ZIC1,ZNF24,KCNT2,AGMO,LYPD6,ZNF177,EML6,ZNF189,UPF3A,SLC30A4,SLC38A1,LINC02210,ADAMTS9,SEMA3B,PARP11,UBE3B,HNRNPA3,FBXO36,FAM219B,RSPRY1,DPF3" MicroRNA hsa-miR-182:mirSVR_highEffct hsa-miR-182:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.73E-118 9.69E-115 9.23E-117 8.50E-116 295 1636 "AS3MT,SYS1,ADCY6,ADORA2A,PTCHD1,ADRA1D,DPY19L2P4,WDR35,ADGRF5,ABCD2,FAM135A,ALK,PDZD4,OGT,CDC42BPA,DPP10,MAP4K3,APBA2,APC,LGR5,ARHGDIA,ARNTL,RGS20,CADPS,LINC00173,NCOA1,NUMB,ATP1B3,ADGRB3,SEC11C,BMPR1B,DST,SYNJ2,ARHGEF7,JAZF1,CA8,CACNB4,CALB1,ISPD,SPAG9,RUNX1T1,ARHGEF1,SYNGR3,LRBA,ARHGEF2,SEPT7,ZMYM4,LRRFIP1,MAGI1,FOXN3,SOCS6,CHRNA4,NDST3,QKI,MAP4K4,CNN3,AKAP7,ARMC8,AKAP5,SLC4A8,BAG4,MYRIP,ZFP28,IGDCC3,SLC35F1,CLOCK,PREPL,TRIM69,AATK,LRIG1,CSNK1G3,SOCS5,DZIP3,ERC2,USP6NL,HDAC9,TMEM170A,ZBTB24,ELMO1,DDX46,RHOBTB1,SACS,DMPK,DNAH9,DYNC1I1,NR1D2,PDCD6IP,DNAJB6,E2F5,AASDH,EBF1,SEZ6L2,EDN1,EDNRB,FCF1,RASGRP1,OPTN,YAF2,FAM13A,PHF20L1,MBNL2,EGR3,AASS,TENM1,RGS17,C8orf37,USPL1,EPHB1,NCALD,IGSF6,MRPL37,VPS26C,EXTL2,EZH1,NRN1,CEP78,GORAB,FGF1,FOXF2,SYNCRIP,COQ5,FAM49B,KHDRBS3,AP4B1,MEGF11,CHL1,SIGLEC8,SEPT9,SULT1C4,GLI2,TOX3,KDM2B,PRUNE2,LPAR4,HAS2,ARHGAP36,ELOVL5,ACOT7,ZDHHC15,LRRC75A,EID2B,IRF8,IDH3B,C2orf72,SOWAHA,SLC35G1,KCNJ5,KCNJ16,KCNN3,STXBP5,KTN1,L1CAM,LIMS1,HECTD2,ASPRV1,SMAD1,PIK3AP1,MAP6,MARK3,MATN3,LRP1B,MEF2C,MEIS2,MIA2,MITF,SAMD5,TAGLN3,NDP,NF1,DNHD1,NPTX1,SLC11A2,NRCAM,IGSF11,OCRL,CHAMP1,PCDH8,PDE4D,GPR173,GPR85,PFKFB3,ABCB1,NALCN,ZNF655,FAM218A,RETREG1,PCDH18,SMIM7,PDZRN4,LRP12,PPM1B,PRKACB,EPDR1,MAPK9,PRPH,SAMD9,CNTLN,PTCH1,ZSCAN32,PTPRG,TMEM145,CEP97,OXR1,RASGRF2,HKR1,ZMAT4,RET,ERI2,GTDC1,TMLHE,ELP2,SNX22,RPL15,FBXW7,SPIN3,PTGR2,ABCA11P,ATAT1,KCNIP1,RYR3,SEMA6D,CSRNP3,ZFP30,KIF21A,PPM1E,SHC4,CHD9,ABLIM3,FAM81A,SEPHS1,ATF7IP,LIMCH1,SNCA,SNRPN,PDZD2,SOX3,HECW1,KDM4C,TEX2,LMO3,LARP4,TTBK2,RGL1,ADHFE1,KANK1,TMEM150C,SYPL1,COBL,CAMTA1,ADGRL3,FBXW11,SATB2,PCDHGB7,DOCK9,PCDHB3,DICER1,ITGB3BP,ZMAT3,TIAM1,ERCC6L2,KAT6B,TPM2,C9orf85,SYNPO2,DCBLD1,TSN,PLEKHH2,BCL2L13,VLDLR,P2RY12,CLDND1,XRCC4,ZIC1,MICU3,MKRN3,TCEAL7,ZNF184,EML6,SPIRE1,DHX33,CADM2,EVI5,STOX2,ADAMTS9,CIAPIN1,FAM47E,EPM2A,FAM13C,AMN1,FZD3,RTN4,PHTF2,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-323-3p:mirSVR_highEffct hsa-miR-323-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.05E-118 1.15E-114 1.08E-116 9.95E-116 262 1280 "ACADM,ABHD6,ADD1,BRAP,PWWP2A,DPY19L2P4,ZNF608,MTUS1,KLHL13,HACE1,TBC1D14,OSBPL8,C1QTNF3,ALCAM,FAM135A,CDC42BPA,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,CDC14B,MADD,ATP1B3,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,JAZF1,SGCE,GPC2,IL33,CA8,KALRN,PTBP2,CERS5,C1orf52,LRBA,RCBTB2,SRSF11,CNOT8,NDST3,NRXN3,FHL5,SLC4A8,ZNF521,ENTPD4,RBM39,CRMP1,APPL1,PHF14,PUM1,RIMS2,DOCK4,HDAC9,KATNAL2,GAPVD1,RIPOR2,DAPK1,BRINP1,ELMSAN1,ZNF804A,FBXL5,WDR20,CDON,DMTF1,CASP8AP2,PDCD6IP,RCAN1,DTNA,ECM2,DNAJB6,GOLT1B,E2F6,EDNRB,ANKRD46,HIPK3,SEMA3D,FRY,YAF2,PHF20L1,EGR3,EIF4G2,TENM1,TMEM35A,EIF1,ENPP6,SH3YL1,ACSL4,SCML2,SLC9B2,POLR1B,SUCO,UBE2E3,MEX3B,SEC23B,PCYOX1,IQCG,FLT1,C2orf88,EFCAB2,ATP6V1H,ATP2C1,MSANTD4,GABRG1,GAD1,ERAP1,KIAA1841,ARFIP1,SESN1,TCERG1,MSL3,FERMT2,ADGRA3,TDRKH,SPACA9,SOX21,MAP4K5,HNMT,ZNF491,MSL1,IDH3A,ZNF181,ZIC5,RBPJ,LRRCC1,SLC35G1,METTL21A,KCNQ3,KIF2A,IPO5,STXBP5,CYP27C1,HECTD2,MARK1,LYPLAL1,MAT2A,MITF,ZNF680,MXI1,NFE2L2,NOVA1,SMIM11A,PCDH8,PDE4B,PDE4D,PLCL1,LRP12,PSAT1,ING3,SH3KBP1,MINDY2,PPM1B,PPP2R5E,RANBP3L,HYDIN,DIRAS2,VPS13C,SNRK,CNTLN,ANKHD1,TMEM260,MARCH1,SLC25A48,USP47,SUSD4,RAP1GDS1,ENOX1,RASGRF1,RBBP6,RADX,KHDRBS2,NUDT11,PBRM1,ZFHX4,EXD2,ALG9,ROBO1,PCMTD2,BAALC,SPIN3,ATP8B4,TCP11L1,LRRK2,RMI1,SEMA6D,CSRNP3,SCN8A,FNIP1,SUPT20H,SGK1,SH3GL3,ARX,CPEB3,CHD9,KANSL3,CPEB4,COA1,ANKRD36,SNCA,MBD5,LMBRD1,USP33,PDZD2,SP4,ZNF423,SPTB,RBM26,LMO3,PBLD,ZNF302,ZC4H2,ERBIN,ZSCAN29,NEK4,COBL,PJA1,CAMTA1,ADGRL3,FBXW11,SATB2,ZFP90,PCDHB15,PCDHB7,GPRIN3,SIK3,ZFPM2,AP4E1,SLC44A1,ERCC6L2,TMPO,FAM124A,NPL,DCBLD1,TSN,ANKRD20A2,PRR18,CCDC14,VSNL1,ZNF781,RICTOR,ZIC2,ZNF711,MICU3,TRIM9,MKRN3,REEP1,ANKS1B,FTSJ1,EMSY,STOX2,ADAMTS9,WNK2,FAM13C,UBE3B,SMIM8,CASC15,ACTR3B,JMJD1C,GAN,SENP7,JPH3" MicroRNA hsa-miR-3161:mirSVR_lowEffct hsa-miR-3161:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.64E-118 2.04E-114 1.90E-116 1.75E-115 305 1755 "CLK4,KDM5D,XKR4,CCDC85A,GALNT13,PWWP2A,ZNF608,INTS2,HECW2,OSBPL1A,OSBPL8,CC2D2A,TAOK1,SEMA6A,SPOP,ALCAM,FAM135A,ANK2,CCDC146,LCORL,MAP4K3,APBA2,APC,VAT1L,TNRC6C,USP37,RGS20,CADPS,ZBTB10,NUMB,ATP1A3,ATP2B2,N4BP2L1,ADAM23,CFLAR,DST,SYNJ1,IL33,CA8,PTBP2,CAST,SPAG9,ZNF501,DCLK1,CLGN,NOG,SRSF11,RAB33A,CLTB,QKI,TMEM184B,FHL5,CNN3,CNR1,FAM149A,COL9A1,RCHY1,AHCTF1,ZNF521,CPS1,CLOCK,NCOR2,SNCAIP,SUSD5,CNTNAP2,FAM169A,PPP1R16B,UBXN2A,RIMS2,GPSM1,USP6NL,CYBB,DOCK4,KATNAL2,ARHGAP24,DCAF8,TM9SF4,MATR3,KIAA0586,KCTD8,MAML1,ZNF804A,KIAA0753,GSDME,SPOCK3,MTX3,SEC16A,ZNF582-AS1,GRIN3A,RAB39B,DMD,DNM1,CDON,PDCD6IP,ARRDC4,DTNA,GOLT1B,E2F5,EDNRB,RASGRP1,SEMA3D,EGFR,MBNL2,ASB3,KCTD3,EIF4G2,DCTN4,EMX2,LRRC17,ENPP6,GPHN,ETV1,F5,DLC1,CHST15,ZSCAN30,PPP1R1B,GORAB,SEC24B,MED12L,GTF2IRD2,FGF12,POLK,HPCAL4,SYNCRIP,FLT1,SLC37A3,C2orf88,EFCAB2,CELF1,STAU2,AP4B1,DOT1L,GALNT15,GABRB3,GALC,IQGAP2,MTHFD2,MSTN,ADAM28,TCERG1,SPIN1,MAP7D2,FERMT2,LNX1,PRUNE2,TDRKH,FUT10,LPAR4,GPR34,TMEM121B,PCLO,CNTRL,GRIA2,PRDM5,COQ10A,KAT7,PSIP1,GUCY1B1,IRAK3,RASSF8,GABARAPL2,HNMT,C9orf129,ZNF546,IL6ST,IL12A,KIFC3,HECTD2,NCOA7,ASPRV1,SMAD1,MARK1,LYPLAL1,MBNL1,KCTD6,POC1B,MITF,MPP2,BLOC1S2,ZNF92,MXI1,MYCN,RTL5,SLC11A2,NTRK2,NUCB2,CHAMP1,GLIPR1L2,PCSK1,CDK18,PRTG,PDE4B,SERPINI1,FAM218A,CCSER2,RETREG1,XRN1,PLCL1,PCDH18,STRN3,PSAT1,SEPT4,DRAM2,PPP2R5E,RANBP3L,PRKACB,PRKCB,RELN,ANKHD1,BDNF-AS,TMEM260,PTPN13,ZNF793,OXR1,RASGRF2,RDX,REV3L,PBRM1,ZFHX4,CARF,GSTCD,NEK11,FBXW7,BAALC,ZC3H14,ABCA11P,MAPK12,PRCD,CASC3,SCAF8,SH3BGR,PPM1E,NUBPL,SLC2A5,EPN2,KBTBD4,NAPB,RCOR3,LIMCH1,MBD5,SNRPN,USP33,HECW1,PEG10,ATP10B,CLSTN2,ITPRID2,NKAIN2,ERBIN,ST5,STAU1,ZSCAN29,SEPT8,NECAB1,PRRC2C,SYT1,COBL,ANKRD28,SMG6,KLHL4,MGRN1,SATB2,TRIM2,RPGRIP1L,PCDHGA11,PCDHB4,TNS2,FRYL,HIF3A,SIK3,ZMAT3,AKTIP,TIAM1,TMEM9,TLR4,NR2E1,RGMB,NR2C2,ZNF346,TRPS1,SSBP2,UBE3A,WRN,XRCC4,PCDH20,MICU3,ZNF32,AGMO,LYPD6,POLR3H,ZNF195,CADM2,DNALI1,RNF103,PLSCR4,PDSS2,FAM13C,FZD3,DOCK8,PHTF2,ADAMTSL3,NHSL1,CPNE4,PRRT4" MicroRNA hsa-miR-548b-3p:mirSVR_lowEffct hsa-miR-548b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.35E-118 2.44E-114 2.26E-116 2.08E-115 322 1957 "RALGAPA1,KCNH8,ACADM,CLK4,FMNL2,ESYT2,BEND6,MTA3,PCDH19,OSBPL8,CC2D2A,ZNF578,UNC79,GPRASP2,SYT13,CDC42BPA,PI16,MAP4K3,VAT1L,USP37,CDK10,PDE8B,ADAM15,BCL7A,NRP2,BLM,FUBP1,SCAPER,THSD7A,CAMK2A,SLC25A14,RUNX1T1,ZNF501,METTL6,USP2,P2RX6,CD38,LRBA,SEPT7,LOC730101,LARGE1,DLGAP2,CCPG1,DIS3L,MS4A7,RAB33A,TPP1,NGEF,CNR1,ARMC8,SLC4A8,COX4I1,MYRIP,ZFP28,FAM171B,SEC31B,CREM,CRMP1,NCOR1,CRYM,SNCAIP,ARHGEF10,SUSD5,PHACTR3,CST3,DZIP3,PPP1R16B,CTH,PUM1,DCAF4,RUBCN,DOCK4,GAPVD1,ARHGAP24,ZNF337,LONRF1,KCTD8,DGKG,TMEM170A,ZBTB24,KIAA0319,DDX46,DMD,DMTF1,DRP2,ARRDC4,DTNA,ABCC5,DNM1L,EDNRB,HIPK3,CNNM1,HEYL,FSD1L,FAM13A,MBNL2,AASS,TENM1,RAB9B,RRAGB,ADGRV1,MRVI1,FAM198B,FCGR1A,ST3GAL6,FCGRT,PRMT5,GORAB,MED12L,GTF2IRD2,SUCO,IP6K2,SYNCRIP,SEMA4D,DCTN2,FAM49B,TPK1,ST6GALNAC3,STAU2,MSANTD4,MEGF10,ERAP1,SIGLEC8,ACSS1,KIAA1841,NEU3,PCDH17,SPIN1,MSL3,TDRKH,FUT10,GPR12,STON1,GRIA2,PRDM5,FAM19A2,ADAMTS6,FAM222A,MUM1,RASSF8,TOX2,FRMD3,ARHGAP36,MIER3,HMGCL,HMGCR,DHX35,HSF2,MSL1,IGF1,LRRCC1,IL6ST,ZNF678,INPP5B,KCND2,KCNN2,LAMA2,SMAD9,GPR155,MAP4,MARK1,LYPLAL1,MAT2A,MBNL1,TM6SF1,SHC3,SCAMP5,MITF,AFDN,ZNF680,BLOC1S2,LYRM9,HNRNPM,NEK1,NELL2,NFYA,NTRK2,CHAMP1,OXTR,P2RX7,CNTN3,PCDH9,PCSK1,PCSK5,PDE1C,PDE4D,NLGN3,PIK3R1,XRN1,GPSM2,FAM216A,PURG,ING3,PPARA,MINDY2,PPM1B,PPP1R1A,PPP2R2B,PPP2R5E,PRKACB,MAPK10,SLC26A11,DIRAS2,DEF8,PIGG,CNTLN,CASTOR1,TMEM231,ZNF793,NWD1,ZNF493,OXR1,KHDRBS2,ERI2,MORC4,GTDC1,RGS3,CCDC82,DCUN1D2,GSTCD,ROBO2,NEK11,SPIN3,ATP8B4,STK32B,NCBP3,SEMA6D,PRCD,SCP2,RASA3,SCAF8,ASAP3,MYO18A,FBXO11,NLGN1,DZIP1,ABLIM3,PEX26,PPP4R3A,TET1,SMARCC2,LIMCH1,SNAP25,KIF13A,TMCC1,MYO16,BDP1,FNBP1,DOK5,NMNAT2,PEG10,LMO3,DIP2A,JMJD6,TACC1,PJA1,MCF2L,DNMBP,TCEA1,WSCD1,KIAA0930,SATB2,ZFP90,TRIM2,TCF12,DOCK9,NSD1,FRYL,PMS2CL,SIRT1,DICER1-AS1,C18orf54,AP4E1,ZNF106,TIAM1,TLR4,NR2E1,RIMBP2,R3HDM1,CSMD1,RGMB,NR2C2,METTL3,RUNDC3B,AMACR,TRO,TRPS1,PPIL6,TST,CLHC1,TUBB1,UBTF,GORASP1,UGT8,BCL2L13,WIPF1,WRN,RICTOR,XPO1,XRCC4,ZBTB14,ZNF19,MICU3,TRIM9,AGMO,LYPD6,TMEM198,EML6,ZNF189,SMARCAD1,CADM2,SLC38A1,PLSCR4,FZD3,DOCK8,KAT6A,SMIM8,NHSL1,FXR1,DPF3,FAM181A,LAS1L" MicroRNA hsa-miR-222*:mirSVR_lowEffct hsa-miR-222*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.66E-118 2.61E-114 2.39E-116 2.20E-115 295 1642 "ACTN1,KDM5D,KLHL32,PCDH19,TXNDC16,CC2D2A,FAM135A,ZFAT,LCORL,PHF12,APC,USP37,ZFYVE28,ARNTL,RGS20,ZBTB10,ATP2A2,TTLL9,BACH1,KSR1,SYNJ1,SYNJ2,ARHGEF7,RAB29,CA8,CACNB4,SPAG9,USP6,SCARB1,DGKI,CDH2,MAGI1,CDO1,TIGD7,NOG,CHN1,NRXN3,PPT2,TPP1,QKI,AKAP5,MAGED1,CNRIP1,CREM,RBM39,TRIM69,SOCS5,VAC14-AS1,PDE4DIP,PPP1R16B,APPL1,RIMS2,USP6NL,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP24,ZFYVE16,ZNF337,MATR3,DBI,PITPNC1,FBXL5,KLHL3,SPOCK3,WDR20,RAB39B,NR1D2,SLC12A6,ARRDC4,DTNA,DNM1L,EDNRB,FCF1,RASGRP1,KLHL5,PHF20L1,C8orf37,CALCRL,DCTN4,LRRC17,GPHN,SPEG,ABCA8,CHST15,SLC9B2,FGF1,FGF13,FHL1,POLK,UBE2E3,MEX3B,FOXF2,PCYOX1,SYNCRIP,EVL,FLT1,PSD2,HVCN1,UFM1,TPK1,CAMKK2,ATP2C1,NSG1,DLL3,HHIPL1,ZMAT1,GALNT15,GGT7,PPARGC1A,MALT1,LYVE1,TXNL4A,STARD3,MAP7D2,WDFY3-AS2,ADGRA3,GPR37,PCLO,TPPP,COQ10A,GSTM5,BVES,AP4S1,PSIP1,RNFT2,FAM222A,ZHX1,FRMD5,ARHGAP36,C9orf129,CPT1C,TCEAL6,DHX35,LRRC75A,IGF1,RBPJ,SCIN,IL6ST,KCND2,IPO5,LAMP2,PAXBP1,HECTD2,MARK1,MARK3,MBNL1,MBP,LRP1B,AFDN,MSI1,NF1,NFE2L2,NFYA,NNAT,NPTX1,NTRK3,SETD4,PDE1C,PDE4B,PFKFB3,NALCN,PIK3C2A,PIK3R1,CCSER2,RETREG1,XRN1,PKM,PLIN1,PRIMPOL,SCHIP1,EPB41L4B,PPP2R2B,PPP3CA,PRKCB,HYDIN,DIRAS2,DCHS2,MASP1,RELN,MTMR10,PTN,ZSCAN32,TTC13,TUG1,PPP2R3C,TMEM255A,FAT4,ZNF493,RASGRF2,RDX,ZMAT4,RIC8B,NUDT11,LGI2,CARF,ROBO1,RORB,BAALC,RTN1,RYR3,CCDC112,RMI1,SATB1,LRFN5,SCN8A,PEAR1,SEC14L1,HSPA4L,CPEB3,SHC4,CHD9,CCDC92,FAM81A,PEX26,DHX30,ZNF430,CPEB4,ANKRD36,INAVA,MYO16,KDM4B,DOP1A,BDP1,DOK5,KDM3A,GLT8D1,MYCBP2,ZBTB43,TSPYL2,RBM26,PBLD,THSD1,ZC4H2,STAU1,CEP68,RGL1,SULF2,KLHL7,ARHGEF9,PLCB1,SYN2,PJA1,TAF9,DMXL2,ZFP90,ZEB1,PCDHB7,PCDHB3,USP32P1,GPRIN3,GPR161,ZMAT3,AKTIP,SLC44A1,TLR4,TMPO,FAM124A,RIMBP2,CDK20,C9orf85,RGMB,STXBP4,TTC3,ZKSCAN5,RPL7L1,UBE2H,UGT8,USP1,BCL2L13,VLDLR,VSNL1,WIPF1,WRN,CLDND1,PCDH20,ZNF711,MKRN3,ZNF138,PCBP1-AS1,SPIRE1,PRDM8,RNF103,HPS4,FIP1L1,FAM47E,PCBP4,PDSS2,HRASLS,RGS7BP,RTN4,JMJD1C,SOCS4,CPNE4" MicroRNA hsa-miR-1259:mirSVR_highEffct hsa-miR-1259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.36E-118 3.00E-114 2.72E-116 2.51E-115 292 1609 "ABCF1,FMNL2,KIAA1211,WDR35,TAOK1,ALCAM,ARHGAP20,BBOX1,FAM135A,AMPH,ANK2,PHF12,PARG,APAF1,CADPS,SLC4A4,MYOM1,ADAM23,BACH1,SEC11C,DST,IL33,KALRN,PTBP2,CBS,METTL6,DGKI,LRBA,SEPT7,FOXN3,SOCS6,PLAA,NGEF,FBXO7,CNN3,CNR1,FAM149A,SLC4A8,ABI3BP,RCHY1,ZFP28,NECTIN3,PREPL,CREM,HAPLN1,TRIM69,LRIG1,ARHGEF10,VCAN,SOCS5,PDE4DIP,PHF14,GREB1,DOCK4,HDAC9,GPRASP1,ARHGAP32,KATNAL2,LIN54,DAPK1,ARMCX4,ARMCX2,MYEF2,WDR20,DMD,DNM1,DPP6,ECM2,WDPCP,OPTN,YAF2,PHF20L1,GOLGA7,IRAK4,USPL1,RCAN2,TLR7,RRAGB,EYA1,ARMCX1,CLVS1,ABCA8,ZNF461,RPS6KC1,TAOK3,DLC1,ZSCAN30,FDFT1,FER,FGF11,FGFR1,POLK,FLT1,JKAMP,NBEA,TRIM16,ATP6V1H,ST6GALNAC3,STAU2,DOT1L,CHL1,GABRG2,GAD1,FAM120B,RAPGEF6,DISC1,GATM,GDF9,ADAM28,GHR,PPARGC1A,TXNL4A,MSL3,ZNF782,ADGRA3,FAM19A2,BVES,MAP4K5,BACH2,HNMT,NEGR1,SMAP1,MSL1,KCND2,KCNH2,KHK,CREG2,LIMS1,PAXBP1,HECTD2,LYPLAL1,MATN3,MEF2C,KCTD6,AFDN,MMP16,ZNF680,ADAM22,NEK1,NTRK2,NTRK3,IGSF11,PAX6,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDCD2,PRTG,PDPK1,GNG2,OLA1,NALCN,ZNF655,PCDH18,PDZRN4,TRHDE,MAPKAP1,STRN3,ING3,EPB41L4B,IRX1,PPM1B,PRKACB,PKIA,MAPK4,VPS13C,PSMA6,QRICH1,CNTLN,ANKHD1,PTK2,TMEM260,PTPRD,PTPRE,C1orf109,PTX3,PEX2,TTC13,ZNF793,ZNF493,OXR1,RBBP6,RADX,MSANTD2,RDX,GTDC1,RIC8B,ZFHX4,ARMC5,CARF,GSTCD,NEK11,ATP8B4,GLDN,LRRK2,MEG3,ZNF331,CCDC112,ATXN2,CASC3,SH3BGR,PPM1E,CPEB3,FNDC3A,ANKRD6,PPP4R3A,WDR47,SLC6A11,SEPHS1,SLC12A2,MTERF2,ATF7IP,CPEB4,RCOR3,ANKRD36,SNAP25,SNCA,ZNF415,SNRPN,PDZRN3,USP33,TRERF1,SOX11,KDM3A,GLT8D1,PEG10,RBM26,SPART,CLASP2,LARP4,ERBIN,NXT2,ELOVL4,DIP2A,NECAB1,VPS13A,SYPL1,COBL,EXOC7,FAM208A,ADGRL3,SATB2,TRIM2,PCDHGA11,SYNE1,PCDHB10,PCDHB4,PCDHB3,NSD1,FRYL,FAM200B,ZFPM2,AKTIP,ERCC6L2,KAT6B,TRIO,AMACR,STXBP4,SGK3,VLDLR,VSNL1,P2RY12,WRN,GUSBP1,ZFP37,ZNF17,KCNT2,TRIM9,ATP6V0E2,FSTL5,ANKS1B,CADM2,PRDM8,RNF103,TUBA1A,ADAMTS9,TRIM16L,PLSCR4,PARP11,PDSS2,FAM13C,FZD3,SMIM8,HNRNPA3,FBXO36,RNF170,KLHDC1,SOCS4,GAN,FAM198A,SENP7" MicroRNA hsa-miR-579:mirSVR_highEffct hsa-miR-579:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-117 6.71E-114 6.04E-116 5.56E-115 316 1892 "RALGAPA1,CLK4,NCKAP5,SYS1,NDRG3,BRAP,PWWP2A,INTS2,KCTD16,KIAA1324,ALCAM,ABCD2,BBOX1,GPRASP2,ZFAT,OGT,DPP10,PHF12,PKP4,APAF1,APC,UPRT,BCAS1,IGDCC4,TMEFF1,CADPS,MARCH3,ZBTB10,NUMB,EIF4G3,ATP2A2,ALDH7A1,DPY19L3,ADAM23,ADGRB3,SEC11C,BID,PROM1,BMPR1B,DST,ARHGEF7,CA8,CALB1,CALM1,KALRN,ISPD,LDB2,SCARB1,CD38,SEPT7,ZMYM4,LRRFIP1,MAGI1,CHN1,CHN2,B4GALT6,NDST3,QKI,MAP4K4,CNR1,CNTN1,AKAP7,COL4A5,SLC4A8,AHCTF1,MYRIP,ZFP28,CLOCK,RBM39,ANKRD44,GDA,ARHGEF10,SOCS5,CCDC144A,HDAC9,KATNAL2,ARHGAP24,CENPL,KIF26A,LONRF1,LIN54,MYEF2,TIAM2,ALKBH8,PLPPR4,SV2B,DMD,DPP6,ACOT8,DTNA,MAMLD1,DNM1L,GOLT1B,E2F5,KLHL5,YAF2,EGFR,AASS,EIF5,IRAK4,COPS4,TENM1,EPB41L2,ENPP6,GPHN,ETV1,F5,ARMCX1,ACSL4,PTK2B,DLC1,FCGR1A,STRADA,FER,FGF14,FGFR1,SLC37A3,C2orf88,NBEA,UFM1,STAMBP,ATP6V1H,ATP2C1,ERGIC3,NSG1,ZNF44,IQGAP2,ERAP1,SIGLEC8,DISC1,IGSF5,SULT1C4,AHDC1,PCDH17,GGTA1P,PPARGC1A,MALT1,WDFY3-AS2,GPR34,ZNF496,BVES,MAP4K5,RASSF8,HAS2,NCKAP1L,DDX19B,INSYN1,BACH2,SYNPO,HNF4G,HNMT,IGFBPL1,USP51,HSF2,SMAP1,IRF8,ZNF546,RBPJ,LRRCC1,SCIN,IL6ST,ZNF678,SLC35G1,KCNN2,LIMS1,HECTD2,NCOA7,SMAD1,MAPT,MARK1,LRP1B,MEST,KCTD6,POC1B,MITF,BLOC1S2,MSR1,MXI1,MYO6,MYO9A,HNRNPM,IDNK,NOVA1,NRCAM,SMIM11A,NUCB2,ZNF713,GPR137C,CNTN3,PCSK5,PDE4D,FAM98B,PIK3R1,ZNF655,PCDH18,PURG,MAPKAP1,STRN3,PSAT1,MAGEL2,EPB41L4B,SH3KBP1,PPM1B,PPP2R5E,PRKACB,PRKCB,MAPK9,HYDIN,RELN,CNNM2,GDPD2,CNTLN,BDNF-AS,MTMR10,PTPRB,PTPRD,TTC13,MARCH1,TMEM255A,CCDC40,FAT4,ENOX1,RADX,RDX,REV3L,PRRT2,FIGN,ZFHX4,CCDC82,ZNF532,CARF,GSTCD,ROBO1,NEK11,ATP8B4,GLDN,LRRK2,FAM161B,RTN1,TRAPPC13,SCN8A,FNIP1,TRA2B,HSPA4L,FNDC3A,NLGN1,WDR37,FAM81A,SLC22A4,CPEB4,ZFP1,RCOR3,ANKRD36,SNAP25,SNRPN,KDM4B,DOP1A,MYCBP2,KDM4C,ZC3H13,CLASP2,POGZ,NKAIN2,ERBIN,ELOVL4,NEK4,TTBK2,DIP2A,ADHFE1,NECAB1,SUPT5H,VPS13A,PLCB1,SYPL1,SYT1,CAMTA1,KIAA1107,DMXL2,CUX2,PCDHB3,PMS2CL,SIRT1,THRA,BHLHB9,TMPO,NPL,C9orf85,SYNPO2,TRPS1,GORASP1,P2RY12,KCNK12,XPO1,CFAP298,MICU3,ZNF45,ATP6V0E2,SPHK2,TCEAL7,FSTL5,EML6,SPIRE1,CADM2,PRTFDC1,STOX2,PRDM10,HPS4,RGS7BP,FAM13C,UBE3B,SMIM8,HNRNPA3,PHTF2,FRMD6,NETO2,NETO1" MicroRNA hsa-miR-218-5p:TargetScan hsa-miR-218-5p TargetScan 1.56E-117 8.75E-114 7.81E-116 7.19E-115 208 779 "ASIC1,ACTN1,ELFN2,GALNT13,PTCHD1,AP2A1,KLHL13,CASKIN1,KCTD16,ABCD2,MARCH4,PDZD4,CDC42BPA,LCORL,PKP4,CASK,ARRB1,RGS20,PDE8B,NUMB,INSYN2B,DPY19L3,DST,FUBP1,CACNA1I,CACNA1G,LDLRAD4,CACNB4,CALM1,RUNX1T1,KRIT1,CDH2,LRRFIP1,L3MBTL4,CDR1,NUMBL,FOXN3,NRXN3,CLCN3,FHL5,CNTN1,FAM171B,HAPLN1,ANKRD44,LRIG1,RIMS4,CNTNAP2,PLXNA4,KIAA0040,ERC2,PLCXD3,PUM1,CCDC144A,ARHGAP32,GAPVD1,RASSF2,AIF1L,DNAL1,DBN1,ELMSAN1,JAKMIP2,ELMO1,RHOBTB1,HS3ST2,NR1D2,CPEB2,DPP6,GOLT1B,EBF1,FAM13A,MBNL2,PLXNC1,GOLGA7,RGS17,PAN3,ERBB4,CEP85L,DNAJC27,MRVI1,CLVS1,NSRP1,KAT8,MED12L,FGF12,FLNC,PSD2,C2orf88,NBEA,CAMKK2,CELF1,FUT9,MPP6,NEURL4,CHL1,GABRB3,PCDH17,PPARGC1A,LYVE1,RAB30,GNAO1,GNG4,PCLO,GRIA2,PTPRT,RNF165,BVES,MIER3,HLF,ELOVL5,CELF5,IDH3A,RBPJ,METTL21A,KCNB1,KCND1,KCND2,KLHL23,KCNN3,KCNQ3,KIF2A,KIT,LAMP2,LIFR,HECTD2,MARK1,MBNL1,LRP1B,MEF2C,SCAMP5,MITF,AFF1,HS6ST3,NFIX,GPR137C,PCDH8,PCDH9,PDE3A,GPR85,PIK3C2A,PIK3R1,PPP2R2C,KANSL1,DIRAS2,RELN,CNNM2,PTPRG,CEP97,RAP1GDS1,RET,FIGN,RFX3,KLHL11,EXD2,KLHDC8A,ROBO1,ROBO2,RORB,PCMTD2,ATP8B4,KCNIP3,ATXN2,SCN2B,SCN8A,SEC14L1,FHOD3,ABLIM3,FAM81A,CCDC88A,COA1,MBD5,KIF13A,MYO16,BDP1,LMO3,CLASP2,NXT2,MPRIP,NECAB1,NUDT10,SATB2,DOCK9,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,GPR161,CBX5,ASXL3,RIMBP2,FLRT2,RICTOR,KCNK12,NDRG4,ANKS1B,CADM2,GDPD5,RNF103,NAV3,ITM2C,HNRNPA3,FRMD6,DPF3,GAN" MicroRNA hsa-miR-548m:mirSVR_highEffct hsa-miR-548m:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-117 9.33E-114 8.26E-116 7.60E-115 307 1788 "KCNH8,CLK4,KDM5D,KLHL32,BRAP,ADORA2A,PWWP2A,FAHD2CP,BEND6,MTUS1,HECW2,OSBPL1A,KIAA1324,WDR35,CC2D2A,SRPX,FAM135A,DPP10,FGD2,CCDC146,MAP4K3,MYH7B,APAF1,EPB41L5,TNRC6C,PPP4R4,CDK13,NUMB,TMEM108,DPY19L3,ADGRB3,PROM1,SYNJ1,C5,CAMK2G,CD38,LRBA,SEPT7,CDH2,MAGI1,TIGD7,SRSF11,B4GALT6,EPS15L1,PLAA,PPT2,CLCN3,C4orf33,QKI,MAP4K4,AKAP6,ABI3BP,RTTN,CNRIP1,SLC35F1,HAPLN1,NCOR1,ABCG1,ERC2,RIMS2,KIAA0408,BOC,DOCK4,HDAC9,DCAF8,TBC1D5,LIN54,MATR3,KIAA0586,TMEM170A,PABPC5,ARMCX4,GSDME,DDX46,CHRDL1,EXOG,DMD,USP3,CDON,CPEB2,PDCD6IP,GOLT1B,EBF1,EDNRA,EDNRB,FCF1,RASGRP1,KLHL5,FRY,FSD1L,PHF20L1,EBI3,GOLGA7,KCTD3,IRAK4,TENM1,PLEKHA1,STARD3NL,EPB41L2,CEP85L,ETV1,TLR7,DLC1,CEP78,FKTN,GORAB,SLC9B2,FGF13,SUCO,UBE2E3,HPCAL4,COQ5,PDLIM5,FAM49B,KHDRBS3,STAU2,AP4B1,OGA,CHL1,ZNF234,DISC1,NEU3,ARFIP1,FREM1,TCERG1,COPS8,RNPS1,ZNF638,CBX1,KDM2B,PRUNE2,GPR37,PCLO,DIDO1,CIT,BTN2A1,RNF165,ADAMTS6,IRAK3,HAS2,DDX19B,MIER3,HMGCR,HNF4G,TCEAL6,SHISA6,ZNF546,RBPJ,INSM1,NME9,SLC35G1,METTL21A,CDH20,KIF2A,IPO5,STXBP5,KTN1,LAMP2,LIMS1,PAXBP1,MAP2,MARK1,LYPLAL1,MATN3,MEIS2,SRSF12,MEST,KCTD6,MIA2,KITLG,POC1B,AFDN,MMP16,ZNF680,BLOC1S2,MSR1,ZNF92,MXI1,MYO9A,BEX5,NOVA1,PCBP3,SLC11A2,PCDH9,PRTG,PDE4A,PDPK1,PLCL1,PURG,MINDY2,PPP2R5E,MAPK9,GRAMD1C,SNRK,CNTLN,MTMR10,PTPRD,C1orf109,ACSM5,STRC,FAM66C,ZNF793,SH3TC2,FAT4,ZNF493,OXR1,MSANTD2,NUDT11,RNASEL,ZFHX4,CCDC82,ZNF532,CCDC25,RORB,PCMTD2,RPL15,CLIP1,S100B,ATXN7,TNFRSF19,GALNT10,SUPT20H,SCAF8,ARX,CPEB3,FNDC3A,ANKRD6,BTBD3,CCDC88A,SLC12A2,ELMO2,BTBD7,CDK5RAP2,RCOR3,LIMCH1,CMTR2,SNRPN,RBM34,USP33,BDP1,SPP1,RBM26,NFASC,ATP10B,NKAIN2,MPRIP,SEPT8,RGL1,PRRC2C,SYNE2,PLCB1,ANKRD28,C12orf76,ADGRL3,AGTPBP1,CUX2,ZEB1,PCDHB9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEK,DICER1,SLC44A1,TIAM1,HEY1,ACTR6,BEX4,KAT6B,SMUG1,DCBLD1,TSC1,SGK3,RPRM,PLEKHH2,USP1,VLDLR,TBC1D15,P2RY12,GUSBP1,ZBTB14,ZIC1,ZNF708,ZNF17,KCNT2,REEP1,ANKS1B,SMARCAD1,KCNAB1,PDSS2,EPM2A,DOCK8,MARCH8,UBE3B,KAT6A,SMIM8,CASC15,RNF170,KLHDC1,FRMD6,NETO2,JPH3" MicroRNA hsa-miR-1303:mirSVR_lowEffct hsa-miR-1303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-117 9.95E-114 8.73E-116 8.04E-115 313 1859 "CLK4,TMEM132B,GALNT16,ADD2,PLEKHH1,MTA3,KLHL13,PCDH19,RTL9,HACE1,KIAA1324,ZNF578,ALCAM,PCDH10,UNC79,GPRASP2,ZFAT,EP400,LCORL,APBA2,KCNAB2,EPB41L5,GAS7,DDO,TNRC6C,PPFIA3,USP37,LGR5,IGDCC4,CASK,ASPA,MARK4,PCDHGB4,NUMB,SLC2A11,ATP6V1G2,RIPK1,ADAM23,ADGRB2,ADGRB3,BBS2,BLM,ARHGEF7,GYG2,SGCE,C5,CACNB4,SLC25A14,SPAG9,RUNX1T1,METTL6,CCNH,P2RX6,SEPT7,DCLK1,EPS15L1,NRXN3,IQCK,ARMC8,AKAP6,LETMD1,SLC4A8,ABI3BP,AHCTF1,CPS1,HAPLN1,ANKRD44,ARHGEF10,SUSD5,SOCS5,PDE4DIP,CNTNAP2,APPL1,PHF14,GPSM1,DCAF4,CYBB,ZFYVE16,EARS2,LONRF1,DGKG,SCRN1,DNAL1,PITPNC1,ELMSAN1,KIAA0319,PLPPR4,WDR20,SEC16A,DLX1,SLC12A6,DNAJB6,ABCC5,WDPCP,EDN1,CNNM1,SEMA3D,KLHL5,TMTC1,APH1A,EGFR,MRO,KMT5B,ASB3,PLEKHA1,ELN,C3orf18,EMX2,EPB41,GPHN,SRRM1,DENND4A,CEP85L,SPEG,EXTL2,KATNAL1,ADGRV1,EYA1,HSPA12B,NSRP1,FAM198B,ACSL4,TAOK3,CEP78,FKTN,SYNCRIP,RGPD5,EVL,PDLIM5,RASL10A,CAMKK2,ZNF605,ERGIC3,MPP6,FYB1,FYN,GABRA3,GALNT15,GALC,SULT1C4,MMADHC,USP19,TTBK1,GLI2,WDFY3-AS2,PRUNE2,GPER1,GPR34,TMEM121B,GRM8,RABL2A,GUCY1B1,HAS2,PADI2,VSIG4,HMGCR,NEGR1,SMAP1,NKD1,IBA57,INPP5B,INSM1,GPR62,KIF5A,IPO5,CYP27C1,LAMP2,SYTL4,HECTD2,MAN2A2,CHST6,CHIC1,TM6SF1,MEIS1,KITLG,AFDN,MMP16,ZNF680,SAMD5,ZC3H12B,NF1,DNHD1,NRCAM,NTRK2,OPA1,ETFRF1,PCDHGC3,PFKFB2,PIK3R1,CCSER2,XRN1,MTRF1L,PDZRN4,TRHDE,LRP12,ING3,DRAM2,PPM1B,KANSL1,PPP5C,RANBP3L,RASGEF1B,TMEM260,PTPRD,CASTOR1,NKAIN1,RAD17,FAM66C,FAT4,NWD1,ZNF493,RBBP8,RADX,TRIM68,PRIMA1,CCDC82,SETD5,TMLHE,EXD2,CYB561D1,ATP8B4,SGSM1,MAP6D1,ABCA11P,ATAT1,FAM192A,SEMA6D,SEC14L1,SUPT20H,CPEB3,FNDC3A,WDR37,EPN2,SEPHS1,SIRT2,TRIM67,SLC11A1,KBTBD4,ELMO2,BTBD7,SLC22A4,ABTB1,ANKRD36,LIMCH1,KIF13A,SNRPN,FAM126B,KDM4B,ZHX3,ERC1,ZNF423,CDK19,RBM26,LARP4,SULF2,SEPT3,NUDT10,ADAMTS17,TMEM150C,ANKRD28,ASTN2,DNMBP,ADGRL3,TCF4,KIAA0930,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,FAM189A1,NSD1,PUM2,AKTIP,BHLHB9,ERCC6L2,KAT6B,DOK6,RGMB,AMACR,STXBP4,TTTY15,PRR18,TUBB2A,HIRA,FLRT2,BCL2L13,MTCH1,P2RY12,RICTOR,XRCC4,ZNF24,TRIM9,CELF4,SLC38A1,TUBA1A,FAM47E,PLSCR4,PDSS2,FZD3,UBE3B,FBXO36,RNF170,KLHDC1,CPNE4,LAS1L" MicroRNA hsa-miR-100*:mirSVR_lowEffct hsa-miR-100*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.21E-117 1.24E-113 1.07E-115 9.89E-115 310 1825 "KCNH8,ACADM,KLHL32,ADORA1,ADRA1D,MTA3,PCDH19,TXNDC16,CC2D2A,ABCD2,PCDH10,FAM135A,OGT,DPP10,EP400,PPFIA4,APBA2,APC,VAT1L,TNRC6C,LGR5,CASK,ZFYVE28,ARNTL,EIF4G3,ATP1B3,STX16,RNF182,ADAM23,RGS9,NRP2,CFLAR,BTK,SGCE,IL33,CA12,CALB1,SPAG9,PRC1,RGN,CD86,CD38,CDH2,CHGB,SOCS6,CNOT8,EPS15L1,NRXN3,SRP14-AS1,ARHGEF6,FAM149A,COL4A5,SUMF2,AKAP5,SLC4A8,BAG4,ZNF521,FAM171B,C2CD2,CREM,TRIM69,ARHGEF10,CSNK1E,CSNK1G3,SUSD5,VAC14-AS1,APPL1,PUM1,PPP6R2,DOCK4,KATNAL2,SNPH,ZFYVE16,IST1,DGKB,PITPNC1,YTHDC1,TIAM2,FBXL5,KIAA0319,GSDME,POM121,SV2B,FAM107B,SEC16A,GRIN3A,DMD,HS3ST2,DOCK2,CASP8AP2,ECM2,MAMLD1,DNAJB6,DNM1L,E2F5,WDPCP,EDN3,EDNRB,RASGRP1,KLHL5,FRY,YAF2,FAM13A,PHF20L1,EGFR,KMT5B,AASS,GOLGA7,COPS4,TENM1,PAN3,USPL1,EIF1,GPHN,SRRM1,NCALD,DNAJC27,RASL12,KATNAL1,CEP78,KAT8,GORAB,SLC9B2,PRKAG2,FLT1,C2orf88,EFCAB2,JKAMP,FAM49B,ZNF605,CELF1,STAU2,MEGF11,GAD1,GALC,RAPGEF6,ERAP1,MTHFD2,DISC1,TUBA8,SESN1,ADAM28,GFRA2,RAB30,LUZP2,DCLK2,FERMT2,LNX1,ADGRA3,PRRC2B,CACFD1,GRM8,FAM19A2,AP4S1,RNFT2,ZHX1,TNFAIP8L3,ELOVL5,AGBL5,HNMT,SMAP1,EID2B,IGF1,ZIC5,RBPJ,INSM1,KCNN2,KTN1,MAT2A,AQP11,MBP,MEIS2,MIA2,PPM1L,ADAM22,MXI1,MYO6,SLC11A2,NRCAM,NTRK3,CNTN3,PAX6,PCSK5,PDE1C,ENPP2,GPR85,NALCN,FAM218A,ZFYVE21,TMEM38A,PLCL1,PURG,STRN3,LRP12,SCHIP1,ING3,POU6F1,PPP2R5E,PPP3CA,KANSL1,RANBP3L,PRKACB,GRAMD1C,BCAS3,TMEM260,STK32A,PTPN13,PTPRG,PID1,CEP97,CCDC40,ENOX1,KHDRBS2,PBRM1,SETD5,ARMC5,MRAP2,NEK11,FBXW7,ZC3H14,ATP8B4,RPS6KA2,EMID1,MEG3,SALL1,SEMA6D,SATB1,CSRNP3,SCN8A,SCP2,CASC3,MRAS,RASA3,HSPA4L,SGK1,SH3GL3,CPEB3,SHC4,FNDC3A,CNKSR2,NLGN1,ANKRD6,WDR47,FAM214B,SIRT2,SLC14A1,DMRTC1,RCOR3,LIMCH1,MBD5,FAM126B,USP33,PDZD2,ZHX3,ZSWIM8,KDM4C,SSTR2,ZC4H2,ERBIN,ZSCAN29,CEP68,NSFL1C,NECAB1,PRRC2C,SYN2,MTCL1,PJA1,CAMTA1,EXOC7,FAM208A,KLHL4,SIN3B,CUX2,ZEB1,SYNE1,DOCK9,NSD1,PUM2,GPRIN3,PCDHA5,CYB561A3,RNF216P1,ITGB3BP,GPR161,MTMR14,ACTR6,TMPO,RIMBP2,PDSS1,STXBP4,SGK3,RPL7L1,WIPF1,XPO1,ZFP37,ZBTB14,KCNT2,TRIM9,EML6,PRTFDC1,SLC38A1,TUBA1A,MDH1B,ITM2C,FAM47E,DOCK8,UBE3B,JMJD1C,NHSL1,KLHDC1" MicroRNA hsa-miR-522:mirSVR_highEffct hsa-miR-522:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-117 1.39E-113 1.20E-115 1.11E-114 297 1675 "RALGAPA1,KCNH8,ASPHD1,CLK4,NCKAP5,XKR4,FMNL2,CCDC85A,PLEKHH1,KIAA1211,BEND6,MTA3,SLC24A4,CASKIN1,OSBPL6,ALCAM,CDC42BPA,DPP10,LRCH2,LCORL,PKP4,BCAS1,CDC14B,ATP2A2,BLM,ST3GAL5,MTMR3,MTMR2,CACNA1I,RAB29,KALRN,VXN,SPAG9,NFS1,CCNH,C1orf52,LRBA,L3MBTL4,DLGAP1,UBE2L6,RCBTB2,SRSF11,CHGB,FAM19A5,C4orf33,CNR1,CNTN1,ARMC8,AKAP6,ABI3BP,AHCTF1,RTTN,ZFP28,ENTPD4,HINFP,ANKRD44,SNCAIP,SUSD5,VCAN,SOCS5,SLITRK5,RIPOR2,ARHGAP24,LIN54,MATR3,KCTD8,DAPK1,ARMCX2,ZBTB24,MYEF2,ZC3H11A,RHOBTB1,SNAP91,GRIN3A,DMD,NR1D2,CPEB2,DMTF1,SLC12A6,DPYSL2,DTNA,FAM78B,DNAJB6,DNM1L,SEMA3D,APH1A,KMT5B,EGR3,AASS,GOLGA7,IRAK4,TENM1,PLEKHA1,EIF1,EPB41L2,ZNF549,ETV1,VPS26C,ADGRV1,EZH1,F5,ARMCX1,CLVS1,ACSL4,DLC1,CHST15,FDFT1,FER,OLFM1,FGF11,FGF12,PRKAG2,SUCO,SYNCRIP,FLT1,NOP56,NBEA,CSPG5,NSG1,RAPGEF6,DISC1,LRRC37A6P,KIAA1841,GCNT2,SULT1C4,ARFIP1,SESN1,PCDH17,PPARGC1A,SPIN1,TOX3,TNRC6A,MSL3,GLUL,ZNF638,GNAO1,PRUNE2,STON1,GPR34,RNF165,PADI2,MIER3,USP51,CELF5,MSL1,IDH3A,SOWAHA,RBPJ,FAM69A,SLC35G1,KCND2,KCNJ16,KCNN3,CREG2,KIT,CYP27C1,STMN1,LMO2,NCOA7,MAT2A,MATN2,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,BLOC1S2,ADAM22,MX1,MYO9A,HNRNPM,NCAM2,NDP,NOVA1,SLC11A2,TBC1D25,IGSF11,CLDN11,PRTG,PDE4D,PIK3C2A,ZFYVE21,TRHDE,EXOSC10,ING3,EPB41L4B,PPM1B,PPP2R5E,PRKACB,DCHS2,SNRK,TMEM260,PTPRB,PTPRE,PEX2,ACSM5,CCDC40,SH3TC2,OXR1,RASGRF1,HKR1,RDX,UBR7,KIF7,LGI2,CCDC82,ZNF532,CCDC25,RPL15,ZC3H14,ZNF671,MCMBP,LRRK2,CLIP1,ZNF331,SALL1,ATXN7,FNIP1,RASA3,SGK1,KIF21A,PPM1E,SHC4,FAM81A,DHX30,CCDC88A,BTBD7,SLC22A4,CDK5RAP2,RCOR3,SNAP25,SNCA,MBD5,SNRPN,PDZRN3,NMNAT2,HECW1,MYCBP2,KDM4C,TEX2,SPTB,LMO3,PBLD,POGZ,DIP2A,SULF2,NECAB1,JMJD6,VPS13A,ADAMTS17,SYPL1,C12orf76,MTCL1,CAMTA1,TCEA1,RPGRIP1L,SYNE1,SLC19A3,SIRT1,AP4E1,TIAM1,TK2,BHLHB9,KAT6B,RUNDC3B,TTTY15,PRR18,FAM155A,UBE2H,LAT2,CLDND1,SLC47A2,PCDH20,ZIC1,ZIC2,KCNT2,LYPD6,ZNF177,UPF3A,MAP3K12,LINC02210,STOX2,ADAMTS9,TMEM178A,MDH1B,WNK3,PDSS2,EPM2A,DNAH10,FAM13C,MRPL47,JMJD1C,RNF170,FRMD6,NETO2,FAM198A" MicroRNA hsa-miR-320e:mirSVR_lowEffct hsa-miR-320e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-117 2.23E-113 1.90E-115 1.75E-114 319 1936 "KCNH8,ABR,XKR4,CCDC85A,ADD1,UNC5A,RNF150,KLHL13,PCDH19,OSBPL1A,KIAA1324,WDR35,SEMA6A,AMT,SEMA7A,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,PHYHD1,LGR5,SFMBT2,CASK,SPTBN4,ARNTL,ZBTB10,RASL11B,TMEM108,STX16,SLC2A11,LINC00847,NRP2,KSR1,DDR1,CALB1,CABP7,CALM1,KALRN,PTBP2,CAMK2A,RUNX1T1,NFS1,LDB2,METTL6,CD86,ENTPD6,C1orf52,SEPT7,DCLK1,CCPG1,CLGN,NOG,CACNA2D2,SRSF11,NRXN3,CNTN1,AKAP7,AKAP6,SUMF2,COL11A2,SLC4A8,C2CD2,RBM39,HAPLN1,ANKRD44,SUSD5,CST3,DZIP3,GREB1,RUBCN,FAM131B,KATNAL2,DGKG,DAPK1,DBN1,ELMSAN1,DGCR5,ZC3H11A,RHOBTB1,SV2B,ZNF582-AS1,SLC29A4,SLC12A6,ACOT8,DTNA,FARSB,DNM1L,GOLT1B,CNNM1,HEYL,PHF20L1,EGR3,ASB3,TENM1,CERCAM,PAN3,USPL1,EIF1,EPB41,EPB41L2,DENND4A,ANKMY1,EYA1,MRVI1,F5,CLVS1,SH3YL1,TMEM132C,SCML2,FCGR1A,SLC9B2,SEC23B,FLNC,HVCN1,FAM49B,ATP2C1,CELF1,STAU2,OGA,FYB1,ZNF44,DENND2A,GAD1,ZNF234,ZNF274,IP6K3,GATM,ALDH1L1,ARFIP1,GFRA2,ZNF276,ZNF638,POLL,DCLK2,GPD2,GPR12,TMEM121B,PCLO,GRIA2,PLCD4,GRM2,GSTT2,RABL2A,MAP4K5,ATXN2L,MIER3,HMGCL,AGBL5,ZNF491,ZDHHC15,SMAP1,MSL1,SOWAHA,IL6R,SLC35G1,KCNK3,KHK,SYTL4,NCOA7,MAP4,MBP,MID1,AFDN,MMP16,MPP2,BLOC1S2,NRBP2,N6AMT1,NACA,ZC3H12B,NDP,NEFM,CNOT4,DNHD1,TBC1D25,CHAMP1,OPA1,ETFRF1,PCDH9,PDE4D,ENPP2,PFKFB2,NLGN3,TMIE,SNX10,ZFYVE21,TMEM38A,GPSM2,JAKMIP1,PMP22,SDK2,PILRA,PPM1B,PPP3CA,VSTM2L,MAPK3,GRAMD1C,MASP1,APTX,TMEM104,PTPRD,CASTOR1,PTPRO,ZNF615,TMEM231,TMEM255A,ZNF493,RASGRF1,GTDC1,RGS3,RIC8B,RNASEL,C12orf49,ALG9,CARF,YY1AP1,PCMTD2,ATAT1,CLIP1,ZNF568,NCBP3,SALL1,ATXN2,SCAF8,FAM102A,WDR37,PPP4R3A,WDR47,FAM214B,PKNOX2,SLC6A8,SEPHS1,SLC12A2,SLC12A4,ELMO2,COA1,CDK5RAP2,TMCC1,USP33,DOP1A,SOX11,NMNAT2,SPTB,NFASC,LMO3,ZNF302,NXT2,ZSCAN29,SEPT8,DIP2A,KANK1,SEPT3,SYNE2,ARHGEF9,SYN2,TACR1,ANKRD12,MTCL1,MLST8,IQCE,ATMIN,TCF4,DMXL2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,DICER1-AS1,ITGB3BP,AP4E1,ARL10,ENHO,TK2,FAM124A,PIK3R5,NPL,NR2C2,PDSS1,AMACR,KCNE5,TTTY15,FAM155A,VLDLR,RBFOX3,WIPF1,XRCC4,PCDH20,TRIM9,MKRN3,TMEM237,FSTL5,PCBP1-AS1,SMARCAD1,MEIS3,SLC30A4,PRTFDC1,NT5M,EVI5,STOX2,PRDM8,RNF103,HPS4,URM1,PARP11,RGS7BP,JMJD1C,NLRP3,TIGD6,NHSL1,NETO1,ST8SIA2,SENP7" MicroRNA hsa-miR-384:mirSVR_lowEffct hsa-miR-384:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.22E-117 2.92E-113 2.47E-115 2.28E-114 305 1772 "ABHD6,C3orf14,SYS1,GALNT16,ADCY6,AXIN2,BEND6,PCDH19,KCTD16,HACE1,KIAA1324,OSBPL8,AK2,CEP126,ABCD2,ARHGAP20,FAM135A,ZFAT,LRCH2,EP400,CCDC146,TNRC6C,ZFYVE28,PDE8B,ASGR1,MARCH3,NUMB,N4BP2L1,RIPK1,ADAM23,CFLAR,KSR1,SCAPER,CASTOR3,CACNA1I,LURAP1,KALRN,PTBP2,CAMK2G,ISPD,SPAG9,ZNF501,P2RX6,ARHGEF2,SEPT7,LOC730101,NOG,SRSF11,FOXN3,MS4A7,TAOK2,RAB28,PLAA,ABCG2,CNN3,ARHGEF6,CNR1,AKAP6,SUMF2,LETMD1,BAG4,RBM39,ANKRD44,GDA,SNCAIP,SUSD5,PDE4DIP,CNTNAP2,CST3,PLXNA4,FAM169A,SLITRK5,UBXN2A,RIMS2,DCAF4,HDAC9,ARHGAP32,DCAF8,KCTD8,DGKB,SCRN1,ARMCX4,MYEF2,MFAP3L,FBXL5,KIAA0319,ZC3H11A,ALKBH8,SNAP91,SGSM2,TMCC2,WDR20,GRIN3A,DMD,DMPK,SLC12A6,PDCD6IP,FAM78B,ABCC5,DNM1L,E2F5,WDPCP,ANKRD46,SEMA3D,TMTC1,YAF2,PHF20L1,GOLGA7,TENM1,DCTN4,EPHB1,CEP85L,SPEG,MRPL10,DNAJC27,EXTL2,NSRP1,TMEM132C,CEP78,ZSCAN30,GTF2IRD2,FGF14,TMEM164,POLK,MEX3B,IQCG,FOXO3,SLC37A3,NBEA,UFM1,PDLIM5,KHDRBS3,STAU2,SARAF,HRASLS5,TRAF3IP2,IQGAP2,ERAP1,ZNF559,C15orf41,DISC1,GATM,SULT1C4,CYP46A1,GFRA2,TNRC6A,ZNF638,RAB40B,LOXL3,GPR12,CCDC184,GPR34,PCLO,ATP2B1-AS1,PLCD4,RASSF8,HAS2,BACH2,HNMT,ZDHHC15,SMAP1,FAM95B1,SCIN,JAK2,SLC35G1,KCNB1,KCNK3,KCNQ3,CREG2,KIF5A,STXBP5,LIFR,LIG4,PAXBP1,MAP2,MAP6,MARK1,MATN3,MBD1,MBNL1,MEIS1,MEIS2,MKLN1,MYO6,MYO9A,ZNF862,ZC3H12B,CNOT4,NOVA1,NTRK2,NUCB2,PAX6,DPY19L2P2,PDE4D,GPR85,NLGN3,RETREG1,GPSM2,PLCL1,PCDHB17P,RANBP3L,RASGEF1B,EPDR1,MASP1,CNTLN,MTMR10,SPDL1,EML5,TTC13,TUG1,PPP2R3C,RASGRF2,KHDRBS2,RNASEL,ROBO2,PCMTD2,CCDC102B,SPIN3,ATAT1,ZNF568,RMI1,CSRNP3,SCN2B,SCP2,SUPT20H,TRA2B,ZFP30,SH3GL3,PPM1E,CPEB3,HKDC1,FBXO11,SEC31A,SLA,SLC2A5,PKNOX2,SLC12A2,ZNF334,ZFP1,RCOR3,MAPKBP1,MBD5,BDP1,TSNAXIP1,SP4,NMNAT2,HECW1,KDM4C,RBM26,SPART,ATP10B,CLASP2,CLSTN2,ITPRID2,SS18,STAU1,ZSCAN29,SEPT3,VPS13A,SYPL1,COBL,SLC37A2,CAMTA1,ADGRL3,ZFP90,CUX2,TPCN2,TCF12,NAT16,NSD1,GPRIN3,RNF216P1,THRA,TLR4,ERCC6L2,FAM124A,BEX4,PRRT1,RASD2,SYNPO2,ELP5,RUNDC3B,TRPS1,TSC1,SSBP2,ZKSCAN5,HIRA,BCL2L13,VGF,WIPF1,ZNF24,KCNT2,ZNF540,LYPD6,ZNF154,ZFAND5,SLC30A4,STOX2,PLSCR4,DOCK8,FBXO36,RNF170,FXR1,IFT88,PRRT4" MicroRNA hsa-miR-890:mirSVR_lowEffct hsa-miR-890:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.46E-117 3.06E-113 2.57E-115 2.36E-114 292 1623 "ADCY6,GALNT13,AXIN2,PLEKHH1,USP31,ESYT2,BEND6,MTA3,SLC24A4,AP2A2,MTUS1,PCDH19,CC2D2A,SEMA6A,FAM135A,AMPD2,OGT,DPP10,PI16,APC,LGR5,TMEFF1,ARNTL,CDK13,CCDC74A,CHRD,NUMB,TMEM108,EIF4G3,ATP1B3,SEC11C,DST,FUBP1,CA4,HAP1,PRC1,P2RX6,SCARB1,MAGI1,COPB2,FOXN3,CHN2,TPP1,ABCG2,CNR1,AKAP6,WHRN,CABP1,SUMF2,LETMD1,SLC4A8,ABI3BP,RCHY1,COX4I1,BAG4,ZNF521,ZNF385A,SLC35F1,AKAP12,CRY2,ANKRD44,GDA,OSBPL3,VCAN,SOCS5,PDE4DIP,PHF14,GREB1,RIMS2,BOC,DOCK4,HDAC9,ARHGAP32,EARS2,DAPK1,SCRN1,B3GAT3,PLPPR4,SPOCK3,FAM107B,CHRDL1,DMD,RCAN1,MAMLD1,EDN1,ANKRD46,FCF1,PHF20L1,MRO,KCTD3,TMEM35A,EMX2,COQ7,NCALD,ZNF549,DNAJC27,KATNAL1,ADGRV1,NRN1,FAM198B,TAOK3,FCGR1A,CEP78,FCGR3A,ZSCAN30,FDFT1,FECH,SEC24B,SUCO,MEX3B,HPCAL4,SYNCRIP,FOXO3,FLYWCH1,C2orf88,SPECC1,STAMBP,KHDRBS3,ABLIM2,ZMAT1,MEGF11,GALNT15,GABRG1,B4GALNT1,ZNF274,DISC1,NEU3,TUBGCP4,GPR162,ADAM28,MMADHC,MSL3,DCLK2,LILRB4,GPR12,CCDC184,STON1,PLPP7,FAM19A2,PADI2,SHISA6,ICA1,MSL1,IGF1,SCIN,INPP5B,ITGAM,KCNK3,STXBP5,L1CAM,TTYH2,LIFR,LMO2,MAPT,LRP1B,MEST,KCTD6,PPM1L,MPP2,LYRM9,ZNF862,ZC3H12B,NDP,NEFH,NEK1,NFYA,NPR2,NTRK2,NTRK3,OCRL,P2RY1,TREM2,PAX6,NALCN,PIK3R1,CCSER2,STRN3,LRP12,RETREG2,SH3KBP1,PPARA,PPP3CA,CEP41,MAPK9,MAPK10,PRPSAP2,MASP1,SAMD9,WBP1L,PTPRD,PTPRO,TUG1,MARCH1,PID1,CEP97,RAD51D,RAP1GDS1,OXR1,RASGRF1,KHDRBS2,MSANTD2,RDX,UBR7,RGS3,PRIMA1,SLC25A36,RNASEL,CARF,PCMTD2,EPHA10,ZNF671,GLDN,SGSM1,KCNIP1,ZNF331,TNFRSF19,KIF16B,CPEB3,FNDC3A,FHOD3,CCDC92,SLA,WDR47,FAM214B,NAPB,BTBD7,RCOR3,SNCA,BDP1,GLT8D1,UHRF1BP1L,ERC1,ATP10B,ITPRID2,ZNF302,SST,LARP4,DIP2A,KANK1,SULF2,NECAB1,SYNE2,RHBDL3,ANKRD28,TACR1,DNMBP,ALG1,TBCEL,FBXW11,WSCD1,TCF4,KIAA0930,CUX2,USP22,SYNE1,TNS2,RNF175,FAM200B,AP4E1,SLC44A1,HEY1,ACTR6,TMPO,R3HDM1,C9orf85,ELP5,TRIO,VGF,TBC1D15,RBFOX3,WRN,RICTOR,GUSBP1,ZNF24,MICU3,MKRN3,CELF4,POLR3H,ZNF189,FTSJ1,LAMP5,ZFAND5,EVI5,PRDM8,HPS4,SEMA3B,GAL3ST3,FIP1L1,AMN1,SMIM8,SOCS4,JPH3" MicroRNA hsa-let-7c:mirSVR_lowEffct hsa-let-7c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.98E-117 3.91E-113 3.25E-115 3.00E-114 308 1809 "GALNT16,GALNT13,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,TXNDC16,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,CDC42BPA,LCORL,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM23,ADAM15,MPDZ,CACNB4,PTBP2,CAST,NFS1,USP6,CD86,LRBA,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,CACNA2D2,ASIC3,MS4A7,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,MFAP3L,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,PDCD6IP,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,EBI3,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,CHST15,GTF2IRD2,IP6K2,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,SIGLEC8,DISC1,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,LINGO1,HAS2,HLF,HMGCL,LRRC75A,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,MYO9A,RTL5,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RX7,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PLCB2,TRHDE,SCHIP1,RANBP3L,MAPK4,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,CASTOR1,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,SPIN3,KIAA0895L,TCP11L1,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,FOXRED1,HSPA4L,CPEB3,ST6GAL1,WDR37,BTBD3,EPN2,FAM214B,SLC6A8,KDM4D,ATF7IP,CPEB4,MAST1,SMARCD3,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,DDN,NFASC,CLSTN2,POGZ,SSTR2,PLCB1,PDLIM2,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,DICER1-AS1,AP4E1,ARL10,ERCC6L2,NPL,CHST5,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,ZNF28,ZBTB38,MEIS3,SIGLEC10,FIP1L1,TRIM16L,ST7,UBE3B,KAT6A,CASC15,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-216a:mirSVR_lowEffct hsa-miR-216a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.19E-117 4.02E-113 3.32E-115 3.06E-114 318 1928 "CCDC85A,ADD1,ADD2,BRAP,ADORA2A,ADRB2,SLC24A4,AP2A2,WDR35,CC2D2A,SPARCL1,SMIM17,SPOP,ALCAM,TRMT9B,AMPH,ZFAT,LCORL,PHF12,PKP4,APAF1,KCNAB2,USP37,PPP4R4,CHID1,SLC4A4,N4BP2L1,DPY19L3,LINC00847,SEC11C,BCHE,NRP2,KSR1,BMP7,BMPR1B,SYNJ1,NAE1,MTMR3,JAZF1,CA8,CA12,CACNB4,CALB1,CALM1,KALRN,PTBP2,CAMK2G,CBS,METTL6,MTMR7,CD38,SEPT7,CDH2,DCLK1,L3MBTL4,LOC730101,CLGN,RCBTB2,SRSF11,MS4A7,PLAA,QKI,TMEM184B,MAP4K4,IQCK,ARMC8,AKAP6,COL4A5,SLC4A8,ABI3BP,SLC35F1,AKAP12,CS,MROH8,SNCAIP,RGS6,LRIG1,OSBPL3,PLXNA4,DZIP3,APPL1,UBXN2A,PHF14,CTH,DOCK4,ZNF337,KCTD8,DGKG,TMEM170A,DAPK1,SCRN1,ARMCX4,KLHL3,DDX46,GUCD1,DNAH9,DMTF1,SLC25A18,ABCC5,DNM1L,E2F5,KLHL5,TMTC1,OPTN,YAF2,TMEM35A,COQ7,DENND4A,ETV1,VPS26C,DNAJC27,TLR7,SIRPB1,F5,RACK1,CHST15,FCGRT,STRADA,FER,MED12L,FGF12,POLK,SUCO,PSD2,NOP56,EFCAB2,NBEA,HVCN1,CAMKK2,OGA,MEGF11,CHL1,GABRB3,C15orf41,TUBGCP4,ARFIP1,PCDH17,GGT7,TOX3,LUZP2,RAB40B,GPR37,PCLO,CNTRL,DIDO1,ADAMTS13,ATE1,SOX21,LINGO1,PSIP1,ADAMTS6,MAN1B1,HLF,FAM95B1,ZIC5,METTL21A,KCND1,GATD1,A1BG-AS1,STXBP5,SYTL4,SMAD1,MAN2A2,MATN3,MBP,MID1,PPM1L,AFDN,XRRA1,MMP16,BLOC1S2,MSR1,NRBP2,ZNF92,HS6ST3,MYO6,BEX5,SFR1,NFE2L2,NTRK2,TBC1D25,IGSF11,OXTR,CNTN3,PAX6,ABCB1,PIK3R1,CCSER2,NLE1,PCDH18,MTRF1L,ANKRD16,LRP12,SCHIP1,RETREG2,SH3KBP1,TATDN3,PRKAR1B,MAPK9,RELN,SAMD9,BCAS3,CNTLN,ANKHD1,TMEM260,ZSCAN2,STRC,FAM184A,ZCWPW1,RBBP6,MSANTD2,ZDHHC4,MRPS18A,LGI2,TMLHE,CARF,CYB561D1,ELP2,ATP8B4,TCP11L1,ATAT1,NCBP3,CCDC112,DGLUCY,ATXN7,TNFRSF19,GALNT10,SCAF8,FAM102A,FERMT1,CPEB3,SHMT2,HKDC1,FNDC3A,NLGN1,ST8SIA1,ABLIM3,SLA,PPP4R3A,FAM214B,CCDC88A,NAPB,ZFP1,SMARCA4,SMARCD3,CMTR2,SNRPN,TMCC1,KDM4B,BDP1,ERC1,ZNF423,ARHGAP26,ITPRID2,LARP4,NXT2,CEP68,STXBP1,NSFL1C,SYNE2,PLCB1,ANKRD28,TACC1,TACR1,MTCL1,TAL1,AGTPBP1,TBCEL,IQCE,NEU4,KIAA0930,DOCK9,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,C18orf54,SLC44A1,ERCC6L2,PIK3R5,SYNPO2,TRO,STXBP4,CLHC1,HIRA,RPL7L1,UGT8,OSBP2,FLRT2,RBFOX3,WIPF1,RICTOR,GUSBP1,XPO1,ZIC1,ZNF711,ZNF708,ZNF19,CRB2,TMEM237,ZFAND5,STOX2,PRDM10,HPS4,CIAPIN1,NAV3,KCNAB1,FAM47E,PCBP4,DOCK8,ST7,KAT6A,CASC15,TTC7A,NETO2" MicroRNA hsa-miR-526b*:mirSVR_highEffct hsa-miR-526b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.70E-117 4.87E-113 3.99E-115 3.67E-114 289 1592 "KCNH8,NCKAP5,SLC24A4,ZNF608,ABCD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,LINC00173,STK33,RASL11B,SLC4A4,ATP1B3,DPY19L3,ADGRB3,NRP2,SCAPER,MTMR3,JAZF1,CALB2,PRC1,USP6,C1orf52,SEPT7,TIGD7,CLGN,CFL2,TAOK2,EPS15L1,ABCG2,IGLON5,AKAP5,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,PLPPR4,SACS,DMD,USP3,DMTF1,DPYSL2,DTNA,DNAJB6,DNM1L,E2F5,SNX29,EDN3,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,GMPR2,EZH1,F8,ACSL4,TAOK3,CORO2B,CEP78,SLC9B2,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,SPECC1,UFM1,PDLIM5,ATP2C1,ST6GALNAC3,FYB1,ZMAT1,GABBR1,B4GALNT1,ERAP1,SYT17,DISC1,ADAM28,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,CIT,AP4S1,IRAK3,HAS2,SMAP1,MSL1,METTL21A,KCNN2,KIF5A,LAMP2,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NACA,NCF2,NDP,SFR1,NELL2,CNOT4,OCRL,OGG1,OPA1,GPR137C,CNTN3,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,RETREG2,EPB41L4B,DRAM2,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,APTX,PIGG,PTPRD,PTPRO,CEP97,TMEM255A,USP47,FAT4,OXR1,RASGRF2,GTDC1,SLC25A36,RNASEL,ZFHX4,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,LRFN5,SH3GL3,SHC4,CHD9,FBXO11,FNDC3A,SYBU,WDR37,PPP4R3A,BTBD3,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,PLCB1,ANKRD12,CAMTA1,MCF2L,ADGRL3,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,PCDHB10,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,KAT6B,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,UCHL1,CCDC14,VLDLR,TBC1D15,VSNL1,XPO1,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,PRTFDC1,SLC38A1,PRDM10,RNF103,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,DPF3" MicroRNA hsa-miR-3176:mirSVR_lowEffct hsa-miR-3176:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.48E-117 5.31E-113 4.31E-115 3.97E-114 308 1811 "ACADM,EMILIN3,GALNT16,TMCC3,PLEKHH1,PWWP2A,RNF150,PTCHD1,SLC24A4,MTUS1,AGT,RTL9,TBC1D14,WDR35,TXNDC16,CC2D2A,HFM1,TAOK1,CEP126,SYT13,FGD2,MYH7B,SMIM29,PPFIA4,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,SEMA4G,ARNTL,PLA2G4C,STK33,MARK4,NCOA1,RASL11B,STX16,ALDH7A1,N4BP2L1,TTLL9,ADAM15,BACH1,ADGRB1,ZNF599,SYNJ2,ARHGEF7,CACNA1G,GPC2,DDR1,CAMK2G,SLC25A14,CLDN10,METTL6,P2RX6,ZBED1,NOG,UBE2L6,SRSF11,SOCS6,FBXO7,SRP14-AS1,MAP4K4,ARHGEF6,AKAP6,NECTIN3,CDC42BPB,SH2B1,ANKRD44,C1QL2,SNCAIP,CSF1,CSF2RA,ARHGEF10,CSNK1E,PPP1R16B,DCAF4,ARHGAP32,GAPVD1,RIPOR2,ARHGAP24,DCAF8,CENPL,ZNF337,TBC1D5,MATR3,IST1,DBN1,ELMO1,KIAA0753,RUSC2,RHOBTB1,KIF19,SEC16A,ZNF582-AS1,CDON,DTNB,TOM1,ABCC5,EDN1,FCF1,HEYL,KLHL5,EGFR,TENM1,HSD17B14,EPB41,EPHB1,SLC43A2,ETV1,PIPOX,F5,NSRP1,FAM198B,TBC1D16,PTK2B,FKTN,STRADA,PRMT5,BAIAP2,PRKAG2,IP6K2,SYNCRIP,AGAP3,RGPD5,PSD2,WDR83,APOPT1,ATP2C1,ST6GALNAC3,FYN,SDCBP2,GABBR1,TRAF3IP2,DENND2A,B4GALNT1,RAPGEF6,IP6K3,MTHFD2,DISC1,INPP5K,ALDH1L1,ARFIP1,MALT1,DHRS4,TCERG1,GLYR1,STARD3,LOXL3,PRRC2B,TMEM121B,GRIA2,GRIN2C,FAM19A2,BVES,SLC2A6,ATOH8,HAS2,PADI2,PACSIN2,MAN1B1,CPT1C,LRRC75A,SHISA6,FAM95B1,MYLK2,NKD1,INPP5B,SLC35G1,KCNN2,GATD1,LIFR,SFXN5,SYTL4,SMAD9,ZNF667-AS1,MAP6,ADAM11,MGAT3,MMP16,GIT1,SAMD5,MXI1,RTL5,MYT1,HNRNPM,NBL1,CCDC13,VWA2,DNHD1,SMIM11A,TBC1D25,OGG1,GPR137C,PCSK5,SEMA5B,TMIE,NLE1,PLCB2,PNMA3,TRHDE,RETREG2,PILRA,POLG,PPM1B,PPP1R1A,TATDN3,PPP2R2C,PPP2R5E,PRKAB2,CYBC1,SNRK,ZIK1,PTPRE,PTX3,TUG1,MSANTD2,CRTAC1,TRIM68,ZDHHC4,PRIMA1,ARMC5,CYB561D1,RORB,SNX22,ATP8B4,LRRK2,FAM161B,FAM192A,MAPK12,ATXN2,PRCD,PEAR1,MRAS,SHC4,ANKRD6,NUBPL,PEX26,KANSL3,SLC6A11,ARHGEF40,SIRT2,CCDC88A,SLC11A1,KBTBD4,ELMO2,ANKRD36,SNRPN,TMCC1,USP33,SOX3,SPATA7,ZSWIM8,ZC3H13,SPTAN1,SPTB,TSPYL2,ATP10B,ST5,MPRIP,ZSCAN29,DIP2A,PHLDB1,SEPT3,RHBDL3,SYN1,SYT1,C12orf76,TAL1,AGTPBP1,IQCE,ATMIN,SYNE1,SLC19A3,OBSL1,USP32P1,FAM200B,CHST8,C18orf54,ENHO,TMEM9,TK2,PIK3R5,RASD2,NPL,ZNF346,ELP5,AMACR,TRO,TRPS1,KCNE5,TSC1,TTTY15,SGK3,CCDC14,CELF4,FSTL5,TMEM198,ZSCAN26,SLC30A4,DNALI1,NAV3,URM1,PCBP4,MARCH8,FAM219B,MSRB3,NETO2,AP3B2,GAN,JPH3" MicroRNA hsa-miR-101:mirSVR_highEffct hsa-miR-101:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.38E-116 7.70E-113 6.21E-115 5.72E-114 268 1365 "SYS1,CCDC85A,DPY19L2P4,ZNF608,OSBPL1A,SPOP,CEP126,UNC79,FAM135A,BEGAIN,DPP10,LRCH2,PPFIA4,APAF1,UPRT,LGR5,TMEFF1,SPTBN4,BARD1,BBS2,SYNJ2,MTMR2,JAZF1,SPAG9,PRC1,CERS5,CCNH,MTMR7,CD86,CBFA2T2,C1orf52,MAGI1,SRSF11,CHN2,NDST3,NRXN3,CLCN3,CLTB,SULT4A1,CNTN1,ARMC8,MYRIP,ARHGEF10,CSNK1G3,SOCS5,PHACTR3,PHF14,PNPLA8,CTH,ZSCAN23,HDAC9,ARHGAP32,LONRF1,KIAA0586,PABPC5,ARMCX2,SPATA2,HEPH,TIAM2,KIAA0753,ZC3H11A,PLPPR4,CHRDL1,EXOG,RAB39B,NR1D2,CPEB2,ABCC5,DNM1L,EDN3,PHF20L1,PLEKHA1,TMEM35A,CALCRL,EIF1,MTSS1L,ZNF549,TLR7,EYA1,SH3YL1,ACSL4,SCML2,RACK1,ST3GAL6,FER,FGFR1,UBE2E3,MEX3B,SYNCRIP,FOXO3,ATP13A4,UFM1,STAMBP,ATP2C1,KHDRBS3,STAU2,GALC,RAPGEF6,IQGAP2,ZNF559,DISC1,ARFIP1,AHDC1,PCDH17,RAB30,GPR75,TNRC6A,ZNF638,ATP2B1-AS1,DIDO1,KAT7,GUCY1B1,HAS2,MIER3,HMGCR,NEGR1,SHISA6,SMAP1,SOWAHA,JAK2,KCNJ16,IPO5,STMN1,LIMS1,PACRG,MAP2,MAP4,MARK1,MBNL1,MEST,KCTD6,MITF,XRRA1,MYCN,NACA,NF1,NOVA1,NRCAM,CHAMP1,LOC100128398,CLDN11,GLIPR1L2,PCDH8,ENPP2,GPR85,GNG2,ZNF655,PURG,MAPKAP1,ING3,FA2H,PRKCB,GRAMD1C,HYDIN,DCHS2,DEF8,SPDL1,PTPRG,PTX3,USP47,ZNF493,RADX,KHDRBS2,REV3L,UBR7,NUDT11,ZFHX4,LGI2,ZNF532,SETD5,CARF,ROBO2,RORB,MRAP2,FBXW7,ATP8B4,ADAL,TCP11L1,KCNIP3,RYR3,RMI1,SEMA6D,ATXN7,SUPT20H,SGK1,CPEB3,FAM81A,PPP4R3A,BTBD3,CCDC88A,SLC12A2,ATF7IP,SMARCA4,MYO16,BDP1,FNBP1,SP2,HECW1,TEX2,POGZ,NKAIN2,ERBIN,NEK4,PRRC2C,VPS13A,SYT1,MTCL1,CAMTA1,TAL1,FBXW11,TCEA1,TCF4,DMXL2,ZEB1,TCF12,CLASP1,NSD1,PCDHAC2,PUM2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,SIRT1,ZFPM2,ZMAT3,HEY1,TK2,ACTR6,BHLHB9,ERCC6L2,RIMBP2,KAT6B,RASD2,RUNDC3B,SSBP2,TTC3,HIRA,FLRT2,PLEKHH2,VLDLR,ZNF781,PCDH20,ZFP37,ZBTB14,ZIC1,ZNF711,ZNF17,TRIM9,MKRN3,TFIP11,SLC30A4,EMSY,CADM2,EVI5,KCNAB1,MPPE1,ST7,KAT6A,PHTF2,ADAMTSL3,JMJD1C,KLHDC1" MicroRNA hsa-miR-200a:mirSVR_highEffct hsa-miR-200a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.29E-116 1.28E-112 1.03E-114 9.44E-114 285 1553 "ABCF1,SYN3,NCKAP5,ADD1,ADD2,PLEKHH1,BEND6,RTL9,KIAA1324,SMIM17,PCDH10,AMPD2,UPRT,TMEFF1,ARNTL,CDK13,STK33,STX16,ATP2A2,ADAM23,BACH1,NRP2,ZNF599,ST3GAL5,MTMR2,JAZF1,GPC2,THSD7A,KALRN,PTBP2,CAST,CCNH,USP6,SEPT7,CDC25B,L3MBTL4,TIGD7,DIS3L,CFL2,CHN2,PPT2,QKI,HECTD1,CNR1,COX4I1,AHCTF1,MYRIP,CPS1,SEC31B,PREPL,CRMP1,TRIM69,MROH8,ARHGEF10,CSNK1E,CSNK1G3,VCAN,PDE4DIP,PLXNA4,ERC2,APPL1,PHF14,ZSCAN23,DCAF4,KIAA0408,DOCK4,HDAC9,DAPK1,DBI,ARMCX2,TMEM130,LYPD1,RHOBTB1,SNAP91,SV2B,GRIN3A,DYNC1I1,CPEB2,ABCC5,YAF2,EGFR,KMT5B,GOLGA7,KCTD3,TMEM35A,PAN3,EPHB1,STX2,IGSF6,ANKMY1,EYA1,DLC1,ST3GAL6,FER,OLFM1,POLR1B,FGF13,SUCO,RGPD5,FLT1,NELFCD,SMC2,UFM1,TPK1,KHDRBS3,CELF1,STAU2,MSANTD4,MEGF11,MEGF10,FAM120B,ZNF234,C15orf41,GCNT2,PPARGC1A,TCERG1,ZNF638,CBX1,KDM2B,LOXL3,GPD1,GPD2,GPR12,PCLO,GRB10,GRIA2,ADAMTS13,GRIN2D,ATE1,GSN,GSTT2,GUCY1B1,MIER3,HLF,ACOT7,HNMT,EID2B,IRF8,RBPJ,FAM69A,INSM1,IPO5,STXBP5,LAMP2,MARK1,AQP11,MBNL1,MEIS2,PPM1L,AFDN,COL28A1,NFE2L2,DNHD1,SLC11A2,NRCAM,OGG1,P2RY1,GPR137C,PCDH8,PCDH9,PCSK5,PDCD2,ZNF655,PLCL1,SMIM7,PNMA3,TRHDE,STRN3,SCHIP1,ING3,PPP2R5E,PRKACB,MAPK9,GDPD1,CNTLN,PTCH1,MTMR10,SPDL1,TMEM260,PTPRD,PTPRE,PTPRG,SH3TC2,FAT4,KHDRBS2,MSANTD2,ZMAT4,REV3L,SETD5,NEK11,TCP11L1,STK32B,LRRK2,ATAT1,CLIP1,NCBP3,FAM192A,SATB1,ATXN7,SCP2,FNIP1,SUPT20H,COPZ1,HSPA4L,SGK1,CHD9,R3HDM2,SEC31A,FAM81A,CCDC88A,SLC14A1,ATF7IP,TET1,CPEB4,RCOR3,ANKRD36,LIMCH1,MBD5,LMBRD1,SNRPN,RBM34,PDZD2,KDM3A,SP4,RBM26,LMO3,ATP10B,CLASP2,POGZ,ITPRID2,ZNF302,NKAIN2,ZSCAN29,TTBK2,KANK1,SULF2,STXBP1,KLHL7,PLCB1,MTCL1,FAM208A,ADGRL3,TBCEL,FBXW11,TCF4,SIN3B,ZEB1,TCF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,TIAM1,ERCC6L2,KAT6B,METTL3,TSN,TSC1,RPL7L1,WIPF1,LAT2,CLDND1,RICTOR,ZNF711,ZNF19,MICU3,KCNT2,ANKS1B,SMARCAD1,EMSY,MFF,FAM13C,MRPL47,PHTF2,JMJD1C,NLRP3,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-593:mirSVR_lowEffct hsa-miR-593:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-116 1.30E-112 1.03E-114 9.50E-114 318 1936 "DGCR6,ASIC1,CLK4,EMILIN3,NCKAP5,SYS1,ADD2,RNF150,PTCHD1,SLC24A4,CASKIN1,AK2,C1QTNF3,USP35,ALCAM,FAM135A,ZFAT,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,USP37,AQP6,PPP4R4,TMEFF1,ARNTL,CDK13,MARK4,NCOA1,NUMB,TMEM108,EIF4G3,ZNF582,ATP6V1G2,RIPK1,ADGRB2,ADGRB3,RGS9,CFLAR,NAE1,CACNA1G,RAB29,CALB2,CALM1,ISPD,RUNX1T1,CBR1,CBS,KRIT1,MTMR7,CBFA2T2,CD38,ZBED1,L3MBTL4,LARGE1,DIS3L,CHN2,VAX2,SRP14-AS1,CNTN1,IQCK,FAM149A,SLC4A8,MYRIP,NRG2,FAM171B,C2CD2,ABCG1,SNCAIP,LRIG1,CSNK1E,OSBPL3,GALNT9,KIAA0408,BOC,DOCK4,HDAC9,GIT2,DNAL1,ARMCX4,ZBTB24,MFAP3L,GSDME,GUCD1,SNAP91,MTX3,FAM107B,USP3,DPP6,ARRDC4,ECM2,TOM1,MAMLD1,ABCC5,WDPCP,SEMA3D,KLHL5,PHF20L1,PLEKHA1,TNK2,MRNIP,RGS17,C3orf18,PAN3,EPB41L2,LRRC17,GPHN,SRRM1,SPEG,FAM198B,TBC1D16,CORO2B,RACK1,CEP78,FKTN,PPP1R1B,GORAB,OLFM1,FGFR3,TMEM164,SUCO,UBE2E3,AGAP3,FOXO3,SLC37A3,TRMO,UFM1,PDLIM5,SARAF,AP4B1,TVP23A,MEGF11,HRASLS5,GAD1,GALC,ZNF274,C15orf41,DISC1,LRRC37A6P,GCK,NFU1,GHR,PPARGC1A,SPIN1,GLI2,ZNF638,KDM2B,GNG4,GPD2,CCDC184,PCLO,PLCD4,CLASRP,ZBTB49,ATOH8,DDX19B,AGBL5,NEGR1,SMAP1,ZNF546,SOWAHA,NKD1,SCIN,A1BG-AS1,STXBP5,PAXBP1,HECTD2,PIK3AP1,MARK1,MBD1,MBP,MEF2C,XRRA1,COL28A1,MYT1,NF1,VWA2,SLC11A2,SMIM11A,NTRK2,OXTR,PCSK5,PDCD2,PDE4B,SLC10A4,GPR85,PFKFB2,PFKFB3,TMIE,SNX10,PLCB2,MTRF1L,PURG,LRP12,MAGEL2,DRAM2,PPM1B,PPP2R5E,CEP41,PKIA,MAPK4,CNNM2,PSD,BDNF-AS,PTPRE,C1orf109,TUG1,TMEM231,NWD1,RASGRF1,GTDC1,RGS3,RGS4,RGS12,PRIMA1,RIC8B,RNASEL,ZFHX4,CCDC82,ALG9,CARF,BAALC,ZNF671,MEG3,HSD11B1L,RTN1,ZNF331,FAM192A,DGLUCY,SALL1,ATXN2,SCN8A,GALNT10,MRAS,KIF21A,PPM1E,ASAP3,SHMT2,HKDC1,FBXO11,FNDC3A,DZIP1,SLC4A3,PPP4R3A,SLC12A4,ELMO2,ATF7IP,OGDHL,SMARCD3,LIMCH1,ZNF415,SNRPN,KDM4C,ZNF423,SPART,ZSCAN29,PHLDB1,KANK1,SULF2,ZC3H4,ARHGEF9,NUDT10,ARC,TACC1,FAM208A,IQCE,TCF4,ZFP90,TPCN2,CLASP1,SYNE1,PMS2CL,AP4E1,GPR161,AKTIP,CDH22,SLC44A1,GALNT17,BHLHB9,PRRT1,CSMD1,PIK3R5,CDK20,TPM2,NR2C2,SMUG1,ELP5,TRIO,RUNDC3B,TRO,RPRM,RPL7L1,UBE3A,UBTF,UGT8,PLEKHH2,BCL2L13,VLDLR,CLIP2,LAT2,CLDND1,PCDH20,CELF4,DPYSL5,ANKS1B,TFIP11,UPF3A,INTS3,SLC30A3,SLC38A1,CIAPIN1,PPP1R3F,ITM2C,PCBP4,DOCK8,FAM219B,CPNE4,SENP7" MicroRNA hsa-miR-152:mirSVR_lowEffct hsa-miR-152:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-116 1.44E-112 1.13E-114 1.04E-113 306 1794 "ABCF1,KCNH8,ASIC1,ACHE,NCKAP5,ADD2,PLEKHH1,USP31,PWWP2A,ESYT2,DPY19L2P4,MTA3,SLC24A4,OSBPL1A,CC2D2A,HFM1,SPOP,SRPX,ARHGAP20,SYT13,AMPD2,ZFAT,OGT,ANK2,CCDC146,KCNAB2,EPB41L5,TNRC6C,LINC00173,CDK13,MARCH3,NUMB,ATP2A2,BACH1,MPDZ,KSR1,SYNJ2,MTMR2,CALM1,KALRN,CAMK2A,USP2,P2RX6,SEPT7,CDC25B,TIGD7,TBRG4,CLCN3,CLTC,FBXO7,FAM189A2,CNR1,IQCK,PCYT1B,LETMD1,ABI3BP,SLC35F1,CRY2,CSF1,PLXNA4,PPP1R16B,APPL1,PHF14,RIMS2,DCAF4,CCDC144A,KATNAL2,DCAF8,TBC1D5,IST1,ARMCX4,ARMCX2,SPATA2,HEPH,ELMO1,RHOBTB1,USP3,DNAH9,CDON,DOCK2,DMTF1,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,ABCC5,SNX29,WDPCP,EDNRA,EDNRB,HEYL,EGFR,KMT5B,RASA4,AASS,EIF4G2,PAN3,EPB41,EPB41L2,RASGRP2,MTSS1L,GPHN,SLC43A2,STX2,TAOK3,SCML2,ST3GAL6,FCGRT,AMOTL2,SCARA3,SEC23B,FOXF2,NBEA,PDLIM5,ATP2C1,ZNF605,CGREF1,GALNT15,GABRG1,GALC,SIGLEC8,DISC1,SEPT9,ALDH1L1,TUBGCP4,SPIN1,TOX3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,TPPP,ADAMTS13,SERP2,GRM2,ZNF496,LINC01089,FAM19A2,RASSF8,FRMD3,HLF,SYNPO,HNMT,AGFG1,ZNF546,IGF1,SLC35G1,KCNJ16,PIK3AP1,MAN2A2,ZFYVE27,MAP4,AQP11,MBD1,MBNL1,MBP,CHIC1,MEIS1,MKLN1,MMP16,MSR1,PTOV1,MYO6,NEXMIF,NACA,NELL2,NFYA,NOVA1,NTRK2,TBC1D25,OPA1,ZNF713,P2RX7,GPR137C,DPY19L2P2,PCSK5,PRTG,PDE4B,PDE4D,PIK3R1,CCSER2,SNX10,ZFYVE21,GPSM2,NLE1,MTRF1L,PRIMPOL,LRP12,ING3,SH3KBP1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,EPDR1,HYDIN,MASP1,SNRK,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,ROGDI,RBBP8,PRRT2,RFX3,KLHL11,RIC8B,ZNF532,CARF,RPL15,BAALC,ZC3H14,EMID1,CLIP1,RTN1,SEMA6D,SATB1,CSRNP3,SCN2B,PRCD,MRAS,SUPT20H,RASA3,AMBRA1,FNDC3A,SYBU,SLA,EPN2,KANSL3,PKNOX2,SLC8A1,CCDC88A,TRIM67,ATF7IP,CPEB4,RCOR3,SNAP25,SNCA,KIF13A,FAM126B,MYO16,PDZD2,KDM4C,TEX2,SPTB,CLASP2,CLSTN2,ERBIN,STAU1,DIP2A,STXBP1,PRRC2C,PLCB1,TMEM150C,SYT1,C12orf76,CAMTA1,TAF9,EXOC7,AGTPBP1,FBXW11,TCF4,ZFP90,DOCK9,PHF24,PCDHB4,GPRIN3,MTMR14,NR2E1,R3HDM1,CDK20,CHST5,RGMB,METTL3,TRPS1,HIRA,UGT8,OSBP2,ZNF709,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,SLC38A1,HPS4,KCNAB1,FAM47E,PARP11,UBE3B,KAT6A,CASC15,ADAMTSL3,FAM198A" MicroRNA hsa-miR-580:mirSVR_highEffct hsa-miR-580:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.62E-116 2.03E-112 1.58E-114 1.46E-113 307 1808 "KCNH8,CLK4,NDRG3,PWWP2A,PTCHD1,DPY19L2P4,MTUS1,OSBPL1A,WDR35,FAM135A,SUGT1P4-STRA6LP-CCDC180,UPRT,ARRB1,NCOA1,NUMB,TMEM108,ATP1B3,ATP2A2,ZNF583,RGS9,ARHGEF7,NAE1,SCAPER,CA8,LURAP1,KALRN,CAST,CH25H,SPAG9,RUNX1T1,SYNGR3,CD38,C1orf52,SEPT7,ZMYM4,CCPG1,COPB2,NDST3,CLTB,C4orf33,LY86,CNN3,COL11A2,TBPL1,BAG4,MYRIP,ZFP28,FAM171B,CLOCK,PREPL,AKAP12,TRIM69,ARHGEF10,CSNK1G3,PDE4DIP,ERC2,UBXN2A,PHF14,PNPLA8,CTH,GREB1,PUM1,DCAF4,USP6NL,CCDC144A,HDAC9,KATNAL2,HDAC4,ZFYVE16,MAML1,DAPK1,AIF1L,MYEF2,FBXL5,GUCD1,RHOBTB1,WDR20,DMD,CASP8AP2,ACOT8,PDCD6IP,ECM2,EDIL3,HIPK3,FCF1,FRY,FSD1L,PHF20L1,MBNL2,PLEKHA1,RGS17,DCTN4,TUBD1,EPB41,EPB41L2,DENND4A,CEP85L,MRPL37,ETV1,DNAJC27,EXTL2,ZNF461,SH3YL1,TUBA1B,SCML2,FDFT1,ZNF589,FER,FGF14,POLK,SCARA3,SEC23B,NBEA,TMEM107,SMC2,ATP6V1H,ATP2C1,ZNF605,ERGIC3,GABRB3,GALC,ERAP1,DISC1,LRRC37A6P,GATM,SULT1C4,PCDH17,GGTA1P,PPARGC1A,LYVE1,DBF4,KDM2B,ZNF782,PRUNE2,PCLO,RNF165,MAP4K5,HNF4G,HNMT,HSF2,MSL1,ZNF181,ZNF546,C2orf72,ZNF678,SLC35G1,KIF5A,LINC00634,LIMS1,SYTL4,HECTD2,NCOA7,MAP4,MARK3,SHC3,MIA2,XRRA1,ZNF680,MSR1,NRBP2,LAYN,NEK1,NF1,NTRK2,P2RY1,DPY19L2P2,PCSK1,PDE4B,OLA1,NALCN,FAM216A,PLCL1,PCDH18,PURG,TRHDE,ING3,PPP3CA,PKIA,MASP1,CNTLN,PTK2,PTPRD,NKAIN1,USP47,SH3TC2,FAT4,ENOX1,OXR1,ZMAT4,RFX3,MRPS18A,SLC25A36,RIC8B,PBRM1,ZFHX4,CCDC82,ALG9,ROBO1,ROBO2,RORB,CCDC102B,RPE,ARMH4,SPIN3,ZC3H14,MCMBP,GLDN,LRRK2,ABCA11P,ATAT1,ZNF354C,ZNF568,AP1AR,DGLUCY,SATB1,SCN8A,SCP2,FNIP1,SUPT20H,TRA2B,KIF21A,SH3GL3,KIF16B,CPEB3,CHD9,FHOD3,CCDC92,NLGN1,SEC31A,ANKRD6,PPP4R3A,SEPHS1,SLC9A5,SLC12A2,NAPB,ATF7IP,TET1,CDK5RAP2,ANKRD36,SNCA,CMTR2,SNRPN,TRERF1,BDP1,KDM4C,PEG10,RBM26,SPART,NFASC,CLASP2,CLSTN2,NXT2,STAU1,ZSCAN29,NEK4,RGL1,DIP2A,ADHFE1,KANK1,NECAB1,ZC3H4,PRRC2C,VPS13A,NUDT10,SYPL1,ADGRL3,ZEB1,PCDHB10,FRYL,SIK3,TIAM1,ERCC6L2,FAM124A,KAT6B,CDK20,SYNPO2,TRO,UBE2H,UGT8,PLEKHH2,WIPF1,GUSBP1,PCDH20,ZNF711,ZNF19,KCNT2,ZNF138,REEP1,TMEM237,MEIS3,UPF3A,EMSY,PRTFDC1,LINC02210,STOX2,KCNAB1,FAM47E,PCBP4,MPPE1,WNK3,EPM2A,ST7,HNRNPA3,FRMD6,NETO2,ZNF30,SENP7" MicroRNA hsa-miR-1271:mirSVR_lowEffct hsa-miR-1271:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.88E-116 2.17E-112 1.69E-114 1.55E-113 289 1601 "DGCR6,KDM5D,PWWP2A,MTA3,KCTD16,ADGRF5,SEMA6A,CEP126,PCDH10,GPRASP2,AMPD2,ZFAT,OGT,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB2,APC,ARNTL,RGS20,LINC00173,NUMB,ATP1B3,BACH1,MTMR3,CACNA1G,MYRF,CALB1,CERS5,P2RX6,SCARB1,EVI5L,L3MBTL4,SRSF11,NRXN3,CLTC,MAP4K4,CNR1,BAG4,CLOCK,ENTPD4,ANKRD44,SUSD5,CNTNAP2,GREB1,RIMS2,USP6NL,CCDC144A,CYBB,DOCK4,ZFYVE16,IST1,TMEM170A,SCRN1,SPOCK2,ELMO1,TIAM2,RHOBTB1,SACS,USP3,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,RCAN1,ARRDC4,DTNA,TOM1,MAMLD1,ABCC5,AASDH,EBF1,SNX29,EDNRB,TMTC1,MBNL2,KMT5B,EGR3,KCTD3,EIF5,ING4,RGS17,DCTN4,EPB41L2,IGSF6,NRN1,ARMCX1,RACK1,CEP78,PRMT5,FER,FGF13,AMOTL2,SUCO,FLYWCH1,CAMKK2,ATP2C1,KHDRBS3,CELF1,CGREF1,SARAF,FYB1,HRASLS5,CHL1,ZNF234,LRRC37A6P,CYP46A1,SESN1,FREM1,PCDH17,TXNL4A,CRCP,TOX3,TNRC6A,AIFM3,STARD3,KDM2B,LUZP2,RAB40B,GPD2,PRUNE2,LPAR4,GPR34,CNTRL,GRM2,ZNF496,GSTM5,GUCY1B1,ICA1,FAM95B1,LRRC25,RBPJ,FAM69A,SLC35G1,KCNB1,KCND2,KCNN3,KIF2A,STXBP5,LAMP2,LIMS1,HECTD2,SMAD1,LYPLAL1,CHIC1,SRSF12,MIA2,MID1,COMMD5,MT1M,N6AMT1,NEXMIF,NCAM2,NEK1,NPTX2,SLC11A2,NRCAM,CHAMP1,LOC100128398,PCDH8,PCDH9,CDK18,PRTG,GPR85,PIK3R1,CCSER2,ZFYVE21,RETREG1,EXOSC10,SCHIP1,MAGEL2,ING3,PPP3CA,VSTM2L,PRKAB2,MAPK9,GRAMD1C,MASP1,PIGG,BDNF-AS,PTK2,PTN,PTPRG,TMEM145,PPP2R3C,SLC25A48,RAD17,ZNF493,OXR1,RET,ERI2,GTDC1,PRIMA1,SLC25A36,CCDC82,TMLHE,ALG9,ROBO2,ELP2,FBXW7,SPIN3,PTGR2,ABCA11P,STX1B,RYR3,SATB1,SCN7A,SCAF8,SHC4,FNDC3A,ARHGEF40,CCDC88A,SLC12A2,SLC14A1,MTERF2,ELMO2,ATF7IP,CPEB4,CDK5RAP2,LIMCH1,KIF13A,FAIM2,TMCC1,FNBP1,GLT8D1,PEG10,SPTB,MCF2L2,CLASP2,TROVE2,SSPO,SEPT8,DIP2A,SYNE2,COBL,TACC1,CAMTA1,ADGRL3,SATB2,TRIM2,TCF12,PCDHGB7,SYNE1,DOCK9,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,TMPO,TPM2,SYNPO2,CLHC1,SGK3,PLPPR2,P2RY12,RICTOR,XPO1,XRCC4,ZBTB14,ZIC2,ZNF23,LYPD6,TCEAL7,EML6,ZNF189,UPF3A,CADM2,PRDM8,PRDM10,VPS35L,ST7,MARCH8,RTN4,UBE3B,KAT6A,PHTF2,FXR1" MicroRNA hsa-miR-148b:mirSVR_lowEffct hsa-miR-148b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.07E-116 3.40E-112 2.61E-114 2.41E-113 309 1835 "KCNH8,ASIC1,ACHE,NCKAP5,ADD2,PLEKHH1,USP31,PWWP2A,DPY19L2P4,OLMALINC,MTA3,SLC24A4,PCDH19,OSBPL1A,CC2D2A,HFM1,SRPX,ARHGAP20,SYT13,ZFAT,OGT,DPP10,ANK2,CCDC146,APC,EPB41L5,TNRC6C,SFMBT2,CDK13,MARCH3,NUMB,ATP2A2,BACH1,MPDZ,KSR1,SYNJ2,DDR1,CALM1,KALRN,CAMK2A,LDB2,USP2,P2RX6,SEPT7,CDC25B,TIGD7,TBRG4,CLCN3,CLTC,FBXO7,FAM189A2,CNR1,IQCK,PCYT1B,AKAP6,LETMD1,ABI3BP,SLC35F1,PREPL,CRY2,CS,CSF1,PDE4DIP,PLXNA4,PPP1R16B,APPL1,PHF14,RIMS2,CCDC144A,KATNAL2,DCAF8,TBC1D5,IST1,ARMCX4,ARMCX2,HEPH,ELMO1,RHOBTB1,HS3ST2,USP3,DNAH9,SLC29A4,CDON,DMTF1,SLC12A6,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,ABCC5,E2F5,WDPCP,EDNRA,EDNRB,HEYL,EGFR,MBNL2,KMT5B,AASS,EIF4G2,PAN3,EPB41,EPB41L2,MTSS1L,EPHB1,GPHN,SLC43A2,STX2,TAOK3,ST3GAL6,FCGRT,AMOTL2,SCARA3,SEC23B,FOXF2,SEMA4D,NOP56,NBEA,POMT1,PDLIM5,ZNF605,GALNT15,GALC,SIGLEC8,SEPT9,ALDH1L1,TUBGCP4,SPIN1,TOX3,AIFM3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,TPPP,ADAMTS13,SERP2,GRM2,ZNF496,LINC01089,FAM19A2,RNFT2,RASSF8,FRMD5,HLF,SYNPO,HNMT,AGFG1,ICA1,ZNF546,IGF1,INPP5B,SLC35G1,KCNJ16,PIK3AP1,ZFYVE27,MAP4,AQP11,MBP,CHIC1,MEIS1,MKLN1,MMP16,PTOV1,NEXMIF,NACA,ZC3H12B,NELL2,NFYA,NOVA1,NTRK2,TBC1D25,OPA1,P2RY1,DPY19L2P2,PCSK5,PRTG,PDE4B,PDE4D,PIK3R1,SNX10,GPSM2,NLE1,MTRF1L,PRIMPOL,LRP12,ING3,MBOAT7,SH3KBP1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,EPDR1,HYDIN,MASP1,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,ROGDI,RBBP8,PRRT2,RFX3,RGS12,RIC8B,ZNF532,BAALC,ZC3H14,CLIP1,RTN1,FAM192A,SEMA6D,SATB1,CSRNP3,SCN2B,SCN8A,MRAS,SUPT20H,TRA2B,RASA3,MYO18A,AMBRA1,FNDC3A,SYBU,SLA,EPN2,KANSL3,PKNOX2,SLC8A1,ARHGEF40,CCDC88A,TRIM67,BTBD7,ATF7IP,CPEB4,RCOR3,IFT122,SNAP25,SNCA,KIF13A,MYO16,PDZD2,BDP1,KDM4C,TEX2,CLASP2,CLSTN2,ERBIN,STAU1,CEP68,DIP2A,STXBP1,PRRC2C,PLCB1,TMEM150C,SYT1,C12orf76,TACR1,TAF9,EXOC7,AGTPBP1,FBXW11,TCF4,ZFP90,DOCK9,PHF24,PCDHB4,GPRIN3,DICER1-AS1,MTMR14,NR2E1,R3HDM1,CDK20,SYNPO2,METTL3,TRPS1,HIRA,UBE2H,UGT8,OSBP2,FLRT2,ZNF709,BCL2L13,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,CADM2,SLC38A1,KCNAB1,FAM47E,PARP11,UBE3B,KAT6A,CASC15,FAM198A" MicroRNA hsa-miR-1254:mirSVR_lowEffct hsa-miR-1254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.15E-116 3.44E-112 2.63E-114 2.42E-113 321 1979 "DGCR6,SYN3,ACADM,SYS1,KLHL32,RNF157,ADD1,KIAA1211,DPY19L2P4,PCDH19,RTL9,ZNF578,C1QTNF1,PCDH10,LTBP4,FAM135A,ZNF687,OGT,PI16,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,EPB41L5,APLP1,NT5C3B,PPFIA3,LGR5,SHROOM2,SEMA4G,MADD,CASK,MARK4,PCDHGB4,NUMB,RASL11B,N4BP2L1,ATP6V1G2,LINC00847,DNAJC27-AS1,CACNA1G,MYRF,BAIAP3,CA4,DDR1,CALB1,HAP1,CAPN3,RUNX1T1,KYAT1,CCNH,P2RX6,CD38,LRRFIP1,DLGAP1,CCPG1,SRSF11,CHN2,CHRNA4,B4GALT6,ARHGAP22,NRXN3,PLAA,STOML1,FBXO7,ARMC8,AKAP6,SLC4A8,COX4I1,SMARCAL1,MYRIP,ZFP28,SLC35F1,CPS1,CDC42BPB,CRYBB1,ABCG1,SNCAIP,OSBPL3,CSNK1G3,VAC14-AS1,KIAA0040,RIMS2,FAM131B,GAPVD1,SNPH,KIF26A,IST1,DAPK3,KIAA0753,TMCC2,DLX1,DMD,DNM1,GOLT1B,WDPCP,PHC2,YAF2,EGFR,TMEM35A,MFSD10,ANKMY1,RASL12,SIRPB1,MRVI1,PTK2B,CHST15,FDFT1,PRMT5,PPP1R1B,MED12L,SCARA3,HPCAL4,RGPD5,EVL,NOP56,POMT1,CAMKK2,SDCBP2,MEGF10,GABRA3,ZNF44,B4GALNT1,ZNF274,MTHFD2,DISC1,SEPT9,KIAA1841,NEU3,CYP46A1,AHDC1,GGT5,CRCP,MSL3,STARD3,ZNF638,GPT2,TDRKH,GPR12,STON1,GRM2,ZNF496,BTN2A1,RNF165,AP4S1,RNFT2,PADI2,BACH2,VSIG4,LRRC75A,SHISA6,CELF5,ICA1,RBPJ,KIAA1755,SLC6A17,ITGAM,GATD1,KIT,A1BG-AS1,PAXBP1,LMO2,SYTL4,NCOA7,LSS,MAN2A2,ZFYVE27,CHIC1,SCAMP5,XRRA1,MSI1,BLOC1S2,ADAM22,PTOV1,LYRM9,MYO7A,FXYD7,P2RY13,NCF2,NFYA,NINJ2,NME4,PCBP3,NUCB2,OCRL,LOC100128398,PCDHGC3,PCSK5,PDE4D,GNG2,PFKFB3,CCSER2,XRN1,PKM,SMOX,SLC25A23,LRP12,POLR2F,DRAM2,PPARA,PPP2R5E,PRKAB2,MAPK9,HYDIN,MASP1,CNTLN,C1orf109,PEX2,TMEM231,SLC25A48,FAM66C,RASGRF1,TRIM68,PRRT2,RIC8B,DCUN1D2,C12orf49,EPHA10,KIAA0895L,MCMBP,MEG3,ABCA11P,ST6GALNAC6,SATB1,SCN2B,PRCD,SCP2,TNFRSF19,GALNT10,RASA3,MYO18A,AMBRA1,FNDC3A,CNKSR2,WDR37,FAM214B,KANSL3,PKNOX2,SLC11A1,NAPB,LGI3,GKAP1,MAST1,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,PDZD2,BDP1,ERC1,SPTAN1,LHPP,ATP10B,SSTR1,ZC4H2,NKAIN2,MPRIP,CEP68,PHLDB1,NSFL1C,ARC,SYT1,MTCL1,FAM208A,PDLIM2,TBCEL,SATB2,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PMS2CL,ARL10,ENHO,TIAM1,TLR4,ERCC6L2,PRRT1,ZNF346,AMACR,TRO,STXBP4,TRPS1,KCNE5,TUBB1,FAM155A,UGT8,VAV1,VLDLR,WIPF1,ZIC1,ZNF45,CRB2,AMZ1,TMEM198,ZNF213,DNALI1,SLC38A1,PRDM8,SEMA3B,URM1,FZD3,DOCK8,CASC15,FAM219B,TIGD6,RNF170,ADAMTS10,SOCS4,LAS1L,JPH3" MicroRNA hsa-miR-145:mirSVR_lowEffct hsa-miR-145:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.84E-115 1.59E-111 1.20E-113 1.11E-112 312 1881 "ABR,ASPHD1,PLEKHH1,FZD9,USP31,FAHD2CP,BEND6,AP2A2,TBC1D14,AK2,PCDH10,OGT,LRCH2,CCDC146,MAP4K3,PPFIA3,CDC14B,IGDCC4,ZFYVE28,ARRB1,RGS20,RASL11B,INSYN2B,SLC4A4,ATP1B3,RNF182,DPY19L3,ADAM23,ST3GAL5,MYRF,KALRN,VXN,RUNX1T1,NFS1,CBS,CLDN10,SCARB1,ZBED1,LRRFIP1,DLGAP1,CCPG1,CLGN,CACNA2D2,SOCS6,CHN2,NDST3,RAB33A,CLTC,NGEF,FBXO7,ABCG2,QKI,SULT4A1,HECTD1,MAP4K4,CNR1,AKAP7,CABP1,LETMD1,ZNF521,CNRIP1,AKAP12,RNF14,CLIP3,CS,RASGEF1C,DZIP3,RUBCN,CYBB,DOCK4,GAPVD1,ZNF337,TM9SF4,DAPK1,DBI,GIT2,DNAL1,ZNF804A,ELMO1,KIAA0319,SACS,SGSM2,MTX3,DNAH9,DPP6,DPYSL2,DTNB,GOLT1B,TSPAN5,CNNM1,FSD1L,FAM13A,SUGP2,APH1A,AASS,ASB3,EIF5,TENM1,CALCRL,SRRM1,ERBB4,CDKL3,CLVS1,ABCA8,PTK2B,CORO2B,RACK1,FCGR1A,FCGR1B,FCGR3A,FER,FGF11,FGF13,AMOTL2,SUCO,ANKFY1,PSD2,EFCAB2,POMT1,SMC2,APOPT1,PDLIM5,ZNF605,NSG1,STAU2,ABLIM2,MEGF11,GABRG2,ERAP1,ZNF276,DBF4,ZNF638,FUT10,CNTRL,STMN2,GRIA2,C1QL4,GRM2,PRDM5,ZBTB45,LINGO1,SLC2A6,RASSF8,FRMD5,BACH2,HMGCR,NEGR1,HSF2,LRRC75A,CELF5,SMAP1,EID2B,IRF8,IDH3A,ZIC5,KNDC1,GPR62,KCNN2,KIF2A,PAXBP1,SYTL4,GPR155,MAP6,MBNL1,MBP,TM6SF1,XRRA1,BLOC1S2,MYCN,MYO5A,MYO6,MYO7A,NEXMIF,NCAM2,NFE2L2,ALDH1L2,SLC11A2,NTRK2,NUCB2,OGG1,LOC100128398,PRTG,PDE4B,ENPP2,PFKFB3,ZDHHC8,SERPINI1,KCTD15,PRIMPOL,PMP22,PRKACB,PKIA,PRKCB,EPDR1,GRAMD1C,PIGG,CNTLN,MTMR10,PTK2,PTPRE,PEX2,NKAIN1,TUG1,TMEM231,PPP2R3C,CEP97,NWD1,RASGRF1,KHDRBS2,ZDHHC14,RDX,ZMAT4,RFX2,RFX3,RGS3,KIF7,RIC8B,DCUN1D2,CARF,ROBO2,CCDC25,GLDN,RPS6KA2,STK32B,MAP6D1,MEG3,HUNK,ZNF568,SEMA6D,LRFN5,GALNT10,SH3GL3,CPEB3,HKDC1,AMBRA1,FBXO11,ANKRD6,DHX30,FAM214B,KANSL3,CCDC88A,SLC12A2,NAPB,BTBD7,SLC22A4,SMARCD3,RCOR3,SNRPN,SOX11,DOK5,NMNAT2,HECW1,UHRF1BP1L,MCF2L2,RBM26,ATP10B,ITPRID2,SST,SEPT8,CEP68,NECAB1,JMJD6,SUPT5H,SYNE2,ARHGEF9,COBL,ANKRD12,TBCEL,MGRN1,TCF4,SIN3B,ZFP90,TPCN2,TRIM2,NAT16,FAM189A1,NSD1,CRTC1,FRYL,SIRT1,DICER1-AS1,ZFPM2,ERCC6L2,TMPO,WBP2,ZNF346,AMACR,STXBP4,TRPM2,TST,PRR18,TUBB1,ZIC2,ZNF28,TCEAL7,REEP1,EML6,ZFAND5,SMARCAD1,MEIS3,DNALI1,SLC38A1,EVI5,LINC02210,WNK2,PLSCR4,DNAH10,DOCK8,PHTF2,JMJD1C,KLHDC1,SOCS4" MicroRNA hsa-miR-1265:mirSVR_lowEffct hsa-miR-1265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.01E-115 1.69E-111 1.27E-113 1.17E-112 297 1705 "ASIC1,SYS1,ACTN1,KLHL32,PWWP2A,KIAA1211,RTL9,OSBPL1A,KIAA1324,AK2,C1QTNF3,ABCD2,ARHGAP20,ALK,ZFAT,CCDC146,SUGT1P4-STRA6LP-CCDC180,EPB41L5,APLP1,UPRT,NT5C3B,AQP6,SFMBT2,SEMA4G,CDK13,MARCH3,PCDHGB4,NCOA1,INSYN2B,ATP1B3,STX16,N4BP2L1,DPY19L3,TTLL9,ADGRB3,MPDZ,BMP7,DST,GPC2,CA12,CACNB4,CALB1,KALRN,HIP1R,USP6,LRBA,EVI5L,LOC730101,TIGD7,UBE2L6,SRSF11,ASIC3,CPNE6,RAB33A,CNTN1,ARMC8,ABI3BP,CLOCK,CREM,SNCAIP,CSNK1G3,CNTNAP2,CST3,SLITRK5,SEC14L5,DOCK4,HDAC9,RASSF2,LIN54,DGKB,TMEM170A,SCRN1,AIF1L,SPATA2,YTHDC1,ELMSAN1,ZBTB24,MYEF2,ELMO1,TIAM2,ALKBH8,WDR20,FAM107B,CPEB2,SLC12A6,DTNA,ECM2,FSD1L,PHF20L1,EGFR,MBNL2,KMT5B,EIF1,EPB41L2,ENPP6,RABEPK,DNAJC27,TLR7,KATNAL1,ADGRV1,CD320,F5,FAM198B,SCML2,FCGR1B,GORAB,AMOTL2,PRKAG2,FOXO3,EFCAB2,TMEM107,TPK1,ATP2C1,DLL3,STAU2,ABLIM2,MEGF11,HRASLS5,CHL1,GABRG2,IQGAP2,INPP5K,ALDH1L1,MSTN,ARFIP1,AHDC1,PPARGC1A,TCERG1,GNG4,GPR34,PCLO,GRIN2D,RNF165,BVES,ADAMTS6,GUCY1A1,IRAK3,RASSF8,PACSIN2,MIER3,ZDHHC15,HSPA1L,LRRC75A,SMAP1,IBA57,SLC35G1,KCNK3,KIF5A,SYTL4,SMAD1,MAP4,MARK1,KITLG,MID1,PPM1L,POC1B,ZNF680,DBNL,ADAM22,MSR1,NRBP2,MYO7A,ZC3H12B,NEK1,NELL2,VWA2,SLC11A2,NTRK2,LOC100128398,OXTR,P2RX7,PAX6,PCDHGC3,PCSK5,PDE1C,GPR85,GNG2,NLGN3,SEMA5B,TMIE,GPSM2,PLIN1,PLXNB1,PDZRN4,STRN3,LRP12,EPB41L4B,POU6F1,PPARA,PPP3CA,PRKAB2,MAPK4,MAPK10,DIRAS2,CNNM2,BCAS3,WBP1L,CNTLN,ANKHD1,PTPRB,STRC,SLC25A48,ZDHHC14,RET,RIC8B,LGI2,CCDC82,TMLHE,ROBO2,SNX22,NEK11,RPS6KA2,STK32B,NCBP3,DGLUCY,ATXN2,LRFN5,PRCD,SMPD3,COPZ1,SEC31A,ST8SIA1,SLC2A5,KDM4D,SLC8A1,TET1,CPEB4,IFT122,ANKRD36,SNAP25,FAM219A,DOK5,KDM3A,SP2,ZSWIM8,ZNF423,DDN,SPART,NFASC,CLASP2,CLSTN2,LARP4,SEPT3,STXBP1,ARHGEF9,VPS13A,PLCB1,AGTPBP1,KLHL4,WSCD1,SIN3B,TRIM2,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,NSD1,GPRIN3,AP4E1,ARL10,TIAM1,TLR4,PIK3R5,SMUG1,NEIL2,STXBP4,PPIL6,SGK3,VSNL1,LGI4,ZBTB14,ZNF23,ZNF24,TRIM9,SLC30A3,EMSY,SLC38A1,FIP1L1,MPPE1,DOCK8,UBE3B,KAT6A,FBXO36,FAM219B,SNX14,NETO1,FAM198A,JPH3" MicroRNA hsa-miR-544:mirSVR_highEffct hsa-miR-544:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.18E-115 1.78E-111 1.33E-113 1.22E-112 318 1954 "ACADM,XKR4,AXIN2,PWWP2A,RNF150,PTCHD1,ADRB2,BEND6,HECW2,PCDH19,HACE1,OSBPL1A,OSBPL8,CC2D2A,AK2,SEMA6A,SPOP,ALCAM,ARHGAP20,PCDH10,DPP10,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,AQP6,ARNTL,PLA2G4C,NCOA1,ATP1B3,ATP2A2,N4BP2L1,ADAM23,BACH1,BBS2,MPDZ,BCHE,PROM1,KSR1,DST,ARHGEF7,GYG2,CACNA1G,CA8,CACNA1A,CACNB4,CALB2,KALRN,CAMK2G,PRC1,ZNF501,CBFA2T2,DGKI,LRBA,CDH2,LRRFIP1,CDO1,CHN2,NDST3,NRXN3,QKI,CNGA3,ARHGEF6,AKAP7,PCYT1B,FAM149A,AKAP6,LETMD1,AKAP5,ZFP28,PREPL,CREM,RBM39,HAPLN1,GDA,RGS6,CSF2RA,ARHGEF10,SIPA1L1,PDE4DIP,DZIP3,PHF14,PNPLA8,DCAF4,GPRASP1,GAPVD1,RIPOR2,LIN54,TMEM170A,DAPK1,KIAA0753,SACS,FAM107B,EXOG,CPEB2,SLC12A6,PDCD6IP,ARRDC4,DTNA,ECM2,MAMLD1,DNAJB6,ABCC5,DNM1L,EDNRA,HIPK3,RASGRP1,FRY,MBNL2,AASS,GOLGA7,COPS4,DCTN4,STX2,IGSF6,GMPR2,ACSL4,SCML2,FDFT1,FER,FGF12,FGFR1,SEC23B,SYNCRIP,TMEM107,SMC2,SPECC1,HVCN1,APOPT1,PDLIM5,STAMBP,ST6GALNAC3,SARAF,MEGF10,ZNF44,GAD1,ZNF234,ERAP1,SEPT9,INPP5K,LRRC37A6P,GATM,FREM1,LYVE1,TCERG1,COPS8,GLI2,TOX3,TNRC6A,CBX1,KDM2B,HTATSF1,GPD2,CCDC184,PCLO,GSTM5,KAT7,AP4S1,ADAMTS6,RASSF8,UBE2QL1,BACH2,HLF,TCEAL6,SMAP1,SOWAHA,RBPJ,KIAA1755,ZNF678,C2CD4C,KLHL23,IPO5,PAXBP1,NCOA7,CLEC18A,MAP2,MAP6,MEST,KITLG,PPM1L,ADAM22,MYO9A,NELL2,NF1,CNOT4,NOVA1,OCRL,CNTN3,PCDH9,PCSK1,GPR85,GNG2,OLA1,XRN1,EPB41L4B,PPP2R5E,PPP3CA,RANBP3L,PRKACB,GRAMD1C,RELN,CYBC1,PIGG,CNTLN,ANKHD1,BDNF-AS,PTN,TMEM260,PTPRG,ACSM5,ZNF615,PPP2R3C,MARCH1,RAD51D,FAM66C,FAT4,NWD1,RASGRF2,RDX,RET,RFX3,RIC8B,TMLHE,ROBO1,ELP2,RPE,NEK11,FBXW7,ZC3H14,MCMBP,ATP8B4,STK32B,ATAT1,NCBP3,SATB1,SCN8A,HSPA4L,SCAF8,ZFP30,SH3GL3,CPEB3,SHC4,FBXO11,FNDC3A,EPN2,WDR47,SLC9A5,ANKRD36,SNRPN,KDM3A,SP4,KDM4C,RBM26,NFASC,ATP10B,CLASP2,POGZ,NKAIN2,ZSCAN29,RGL1,NSFL1C,PLCB1,COBL,MMS19,ANKRD12,TAF9,ADGRL3,KIAA1107,TBCEL,TBL1X,TCEA1,ZFP90,ZEB1,CLASP1,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,HIF3A,SIK3,PMS2CL,ITGB3BP,AP4E1,AKTIP,ASXL3,NR2E1,ERCC6L2,TPM1,C9orf85,SYNPO2,RUNDC3B,PPIL6,TTTY15,TTC3,TUBB1,FAM155A,UGT8,CCDC136,WIPF1,ZBTB14,KCNT2,ZBTB38,ZSCAN26,SPIRE1,NT5M,RNF103,ADAMTS9,FIP1L1,DNAH10,CASC15,TRAM2-AS1,KLHDC1,GAN" MicroRNA hsa-miR-376a*:mirSVR_lowEffct hsa-miR-376a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.28E-115 1.84E-111 1.36E-113 1.25E-112 301 1752 "RALGAPA1,CLK4,GALNT16,ADCY6,BRAP,BEND6,DPY19L2P4,ZNF608,CASKIN1,PCDH19,RTL9,OSBPL1A,KIAA1324,WDR35,HFM1,ARHGAP20,PCDH10,FAM135A,PITPNM2,ZFAT,OGT,C6orf89,PHF12,PARG,EPB41L5,PHYHD1,TMEFF1,ZFYVE28,RNF182,DPY19L3,DOCK11,BACH1,ADGRB1,SEC11C,BCL7A,BLM,SYNJ2,C5,IL33,CACNA1A,CALM1,CAMK2A,CAMK2G,ISPD,CBLN1,RGN,MTMR7,SLC16A4,SEPT7,L3MBTL4,LOC730101,CDO1,SRSF11,CHN2,NDST3,NGEF,C4orf33,QKI,CNN3,CNR1,COX4I1,CNRIP1,FAM171B,GDA,MROH8,ARHGEF10,VCAN,VAC14-AS1,FAM169A,APPL1,UBXN2A,PUM1,RUBCN,USP6NL,FAM131B,HDAC9,ZFYVE16,MAML1,IST1,DGKB,DAPK1,PABPC5,GIT2,PITPNC1,JAKMIP2,B3GAT3,TIAM2,FBXL5,ALKBH8,POM121,SPOCK3,DLX1,DMD,CPEB2,DRP2,PDCD6IP,ARRDC4,ECM2,AASDH,EDN1,TMTC1,FAM13A,MRO,MBNL2,KMT5B,IRAK4,PLEKHA1,RGS17,LRRC17,GPHN,CEP85L,ETV1,EXTL2,ADGRV1,NRN1,FAM198B,RACK1,SEC24B,MED12L,FOXO3,PSD2,NOP56,NBEA,HVCN1,APOPT1,PDLIM5,ERGIC3,KHDRBS3,NSG1,ZMAT1,GALNT15,GABRG2,ZNF234,IP6K3,DISC1,KIAA1841,ALDH1L1,TUBGCP4,BRD8,TNRC6A,MSL3,MAP7D2,RAB40B,FUT10,LPAR4,CNTRL,FAM107A,HMGCR,HNF4G,ZDHHC15,SMAP1,IL6ST,JAK2,KCNJ16,STXBP5,SYTL4,MAP4,MAT2A,MATN3,MBNL1,LRP1B,MEF2C,KITLG,MID1,BLOC1S2,MT1M,NRBP2,MYO6,MYO7A,ZC3H12B,NEK1,NELL2,NF1,NFE2L2,OXTR,P2RY1,CNTN3,PCDH9,PFKFB3,PIK3R1,XRN1,GPSM2,NLE1,PLIN1,PLTP,MTRF1L,PURG,TRHDE,SEPT4,DRAM2,PPM1B,PPP2R5E,PPP3CC,PRKACB,MAPK9,MASP1,SAMD9,NCR3LG1,STK32A,PTPRB,PTPRG,RIPOR1,ZNF615,PID1,ACSS3,IQSEC3,ZMAT4,RET,ERI2,GTDC1,RGS3,SLC25A36,ZNF532,KLHDC8A,ALG9,ROBO2,MRAP2,EPHA10,TCP11L1,LRRK2,RXRA,TRAPPC13,FAM192A,AP1AR,SEMA6D,SCP2,GALNT10,TRA2B,HSPA4L,PPM1E,ST6GAL1,WDR37,PPP4R3A,CCDC88A,SLC14A1,ZFP1,SMARCA4,OGDHL,LIMCH1,CMTR2,FAIM2,SNRPN,FAM126B,DOP1A,BDP1,UHRF1BP1L,PEG10,CDK19,LMO3,ITPRID2,SSTR1,ERBIN,SEPT3,STXBP1,JMJD6,FBXW11,TCF4,DMXL2,SATB2,TRIM2,HIF3A,CCDC173,FAM200B,C18orf54,ARL10,ACTR6,ERCC6L2,FAM124A,TNS1,TP53BP1,C9orf85,ANKRD20A2,SSBP2,ZNF610,UBE2H,FLRT2,PLEKHH2,P2RY12,CLDND1,GUSBP1,XRCC4,ZIC1,ZIC2,ZNF17,MICU3,TRIM9,ZNF70,ZNF142,FSTL5,MEIS3,CADM2,PRTFDC1,DNALI1,SLC38A1,PRDM10,KCNAB1,PARP11,FAM13C,DOCK8,JMJD1C,NHSL1" MicroRNA hsa-miR-367*:mirSVR_lowEffct hsa-miR-367*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.01E-115 2.24E-111 1.65E-113 1.52E-112 299 1730 "AS3MT,EMILIN3,KDM5D,TMCC3,GALNT13,ADORA1,USP31,KIAA1211,ADRA1D,BEND6,MTA3,KIAA1324,OSBPL6,AK2,HFM1,ALCAM,PKP4,APC,UPRT,DDO,PHYHD1,VAT1L,PPFIA3,ATP1B3,SLC2A11,DOCK11,MPDZ,SYNJ2,LDLRAD4,CA8,CALB2,CAMK2G,RUNX1T1,CBR1,CLDN10,LDB2,CBFA2T2,CLGN,NUMBL,DIS3L,SRSF11,LHX2,QKI,RAB26,ARHGEF6,AKAP7,SUMF2,MYRIP,RBM39,CLIP3,SNCAIP,RGS6,SOCS5,PDE4DIP,PHACTR3,UBXN2A,CTH,DCAF4,GPRASP1,ARHGAP32,TBC1D5,LIN54,KIAA0586,KCTD8,DGKB,SCRN1,AIF1L,ARMCX4,HEPH,RUSC2,SV2B,SGSM2,TMCC2,DMD,NR1D2,CDON,DMTF1,SLC12A6,DPP6,DRP2,RCAN1,DTNA,TOM1,DNM1L,WDPCP,TMTC1,FRY,MBNL2,KMT5B,EGR3,EIF4G2,IRAK4,EPB41,LRRC17,EPHB1,RABEPK,ANKMY1,TLR7,EXTL2,ADGRV1,EYA1,HSPA12B,NSRP1,RPS6KC1,TMEM132C,DLC1,STRADA,SLC9B2,FGF1,OLFM1,FGFR1,SUCO,AGAP2,SYNCRIP,IQCG,SEMA4D,ATP13A4,ANKFY1,FLYWCH1,EFCAB2,UFM1,ZNF605,MPP6,MEGF10,GABRA3,GABRB3,ERAP1,DISC1,CYP46A1,GFER,GFRA2,PCDH17,CRCP,RAB30,TOX3,GNAL,GPR12,GRB10,GRIA2,ADAMTS13,CIT,AP4S1,RNFT2,C9orf129,NEGR1,C2orf72,RBPJ,KNDC1,KIAA1755,SLC6A17,KCND1,KCNN3,STXBP5,TTYH2,LIMS1,PAXBP1,MAP2,MAP6,MARK1,MAT2A,MBNL1,MBP,EFHB,LRP1B,MEIS1,MIA2,XRRA1,ZNF680,PTOV1,MYO7A,MYO9A,CNOT4,NOVA1,PCBP3,PCDH9,PCSK1,CDK18,PFKFB4,NLGN3,SERPINI1,SEMA5B,ZNF655,SNX10,PLCB2,PLCL1,ANKRD16,ING3,POU6F1,CCDC144B,MAPK4,MASP1,LAMA1,PTPRE,CASTOR1,PTPRG,PTPRO,RAD17,ZCWPW1,RASGRF2,MSANTD2,RET,RGS4,RGS12,LGI2,GSTCD,ROBO2,MRAP2,ARMH4,MCMBP,LRRK2,ABCA11P,STX1B,S100B,SCN2B,PRCD,FNIP1,FOXRED1,SUPT20H,TRA2B,ARX,CHD9,ANKRD6,PPP4R3A,RADIL,SLC11A1,ZNF334,SLC14A1,ELMO2,TET1,ZNF667,ANKRD36,SNAP25,MBD5,KIF13A,SNRPN,KDM4B,PDZD2,SP4,GLT8D1,PEG10,ZC3H13,NFASC,PBLD,SSTR1,ZC4H2,SSPO,ZSCAN29,ELOVL4,ADHFE1,SULF2,ARHGEF9,SLC37A2,C12orf76,TBCEL,IQCE,FBXW11,SMG6,SIN3B,ZFP90,TPCN2,TCF12,DOCK9,SLC19A3,RNF175,FAM200B,PMS2CL,SIRT1,RELL2,PIK3R5,C9orf85,NEIL2,STXBP4,UBE3A,FLRT2,BCL2L13,CCDC14,RBFOX3,ZNF24,TRIM9,AGMO,MKRN3,ANKS1B,ZNF213,SLC38A1,LINC02210,HPS4,CIAPIN1,URM1,MPPE1,PDSS2,RGS7BP,FAM13C,SMIM8,CASC15,TRAM2-AS1,NHSL1,KLHDC1,ST8SIA2,LAS1L" MicroRNA hsa-miR-106a*:mirSVR_lowEffct hsa-miR-106a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.14E-115 2.87E-111 2.10E-113 1.93E-112 313 1897 "ACADM,KDM5D,XKR4,NDRG3,PLEKHH1,KIAA1211,BEND6,SLC24A4,PCDH19,HACE1,OSBPL8,CC2D2A,SMIM17,EP400,CCDC146,SUGT1P4-STRA6LP-CCDC180,APC,TNRC6C,LGR5,RGS20,MARCH3,MARK4,ZBTB10,BACH1,LINC00847,BBS2,CFLAR,KSR1,CACNB4,KALRN,USP2,SEPT7,DLGAP1,TIGD7,CLGN,NOG,RCBTB2,SRSF11,FOXN3,CHRNA4,CNOT8,NRXN3,PLAA,STOML1,SULT4A1,CNN3,ARHGEF6,SUMF2,AKAP5,MAGED1,SMARCAL1,MYRIP,ZNF521,SLC35F1,CDC42BPB,PREPL,CREM,ENTPD4,RBM39,RNF14,GDA,SNCAIP,CSF1,CSF2RA,LRIG1,OSBPL3,CSNK1G3,VCAN,SOCS5,PHACTR3,PHF14,CTH,ARHGAP32,ARHGAP24,LONRF1,LIN54,AIF1L,GIT2,SPATA2,TIAM2,GSDME,GUCD1,SACS,DYNC1I1,CDON,DMTF1,CASP8AP2,DPYSL2,RCAN1,ARRDC4,DTNA,AASDH,SNX29,WDPCP,ASB3,C3orf18,CALCRL,EPHB1,STX2,SPEG,DNAJC27,TBC1D16,ACSL4,TAOK3,SCML2,RACK1,ST3GAL6,STRADA,GORAB,FER,POLK,SUCO,SYNCRIP,AGAP3,SEMA4D,FLT1,ANKFY1,JKAMP,NBEA,UFM1,ATP2C1,STAU2,MEGF10,GABRB3,TRAF3IP2,DENND2A,GALC,C15orf41,TUBGCP4,SULT1C4,SESN1,ADAM28,MMADHC,RNPS1,TOX3,LUZP2,LNX1,GPR12,MCHR1,RABL2A,SOX21,MAP4K5,IRAK3,RASSF8,ZHX1,FRMD5,C9orf129,ZDHHC15,TCEAL6,ZIC5,RBPJ,INPP5B,INSM1,NME9,JAK2,KCNB1,GPR62,KIF2A,KTN1,LAMP2,LIFR,LIG4,PAXBP1,NCOA7,MAP2,MARK3,MATN3,MBP,POC1B,SAMD5,BLOC1S2,NEXMIF,MYT1,BEX5,NF1,NFE2L2,ALDH1L2,NOVA1,NOVA2,NTRK2,P2RY1,PCDH9,PDE1C,GPR85,PFKFB2,PLCL1,PLIN1,TRHDE,LRP12,PKIA,EPDR1,MAPK9,HYDIN,LAMA1,PTCH1,MTMR10,PTN,TMEM260,PTPRB,PTPRD,PTX3,PID1,CEP97,USP47,SH3TC2,RASGRF1,RET,MORC4,PBRM1,CARF,ROBO1,ROBO2,CCDC25,PCMTD2,FBXW7,GLDN,ATAT1,AP1AR,SEMA6D,ATXN7,SUPT20H,HSPA4L,SGK1,PPM1E,HKDC1,R3HDM2,NUBPL,SLA,BTBD3,SLC6A11,SLC11A1,SLC14A1,NAPB,ATF7IP,FAIM2,MYO16,TRERF1,FNBP1,SP2,ZSWIM8,SP4,MYCBP2,KDM4C,TEX2,ZNF423,MCF2L2,ITPRID2,SSTR2,LARP4,ADHFE1,SEPT3,STXBP1,KLHL7,SYNE2,SYN1,SYPL1,TBCEL,TCF4,SATB2,TCF12,SZT2,DOCK9,PCDHB7,FRYL,SIK3,RNF216P1,PMS2CL,DICER1,ITGB3BP,TIAM1,TPM1,NPL,TPM2,SYNPO2,TRPS1,DCBLD1,TSN,SSBP2,ZKSCAN5,UBC,EIF4ENIF1,UBE3A,GORASP1,PLEKHH2,TBC1D15,P2RY12,LAT2,ZIC1,ZNF711,ZNF24,ZNF28,CELF4,ZNF142,ZNF154,POLR3H,ANKS1B,UPF3A,ZXDA,EMSY,STOX2,PRDM8,PRDM10,HPS4,CIAPIN1,FAM47E,TRIM16L,PLSCR4,PARP11,PDSS2,DNAH10,FZD3,SMIM8,FBXO36" MicroRNA hsa-miR-888:mirSVR_lowEffct hsa-miR-888:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.57E-115 5.35E-111 3.88E-113 3.57E-112 320 1986 "RALGAPA1,ABR,ADD1,BRAP,PTCHD1,ADRA1D,SLC24A4,PCDH19,OSBPL1A,TXNDC16,CC2D2A,HFM1,SEMA6A,SRPX,ABCD2,FAM135A,TRMT9B,ZFAT,PPFIA4,PKP4,APBB2,GAS7,UPRT,VAT1L,SHROOM2,CDC14B,SEMA4G,PPP4R4,CASK,TMEFF1,SPTBN4,ZBTB10,NCOA1,NUMB,TMEM108,ATP6V0A1,SEC11C,NRP2,PROM1,FUBP1,BTK,GYG2,GPC2,DDR1,CACNB4,PTBP2,CAST,NFS1,ZNF501,CD86,CD38,DCLK1,CCPG1,CHN1,LHX2,CLTC,CNN3,ARHGEF6,CNTFR,FAM149A,TBPL1,RTTN,ZFP28,FAM171B,RBM39,CS,CSNK1E,OSBPL3,CSNK1G3,DZIP3,APPL1,RUBCN,KIAA0408,MATR3,KIAA0586,SCRN1,IP6K1,DBI,DNAL1,ARMCX4,SPATA2,YTHDC1,MFAP3L,KIAA0319,SV2B,DLX1,EXOG,DMD,USP3,SLC12A6,MAMLD1,AASDH,SEZ6L2,PHC2,HIPK3,RASGRP1,CELSR3,MRO,EGR3,EIF4G2,EIF5,COPS4,USPL1,EPB41L2,STX2,ETV1,EXTL2,NSRP1,FAM198B,SH3YL1,TMEM132C,POLR1B,SPSB4,FGFR3,POLK,SUCO,MEX3B,IQCG,FAM49B,PRELID3A,ERGIC3,SARAF,AP4B1,TVP23A,OGA,GALC,SRCAP,GDF9,GFRA2,PCDH17,DBF4,SPIN1,MSL3,GLUL,ZNF638,GNAO1,TDRKH,FUT10,STON1,TMEM121B,PCLO,FAM19A2,RNF165,GSTM5,KAT7,BVES,SOX21,PSIP1,ADAMTS6,RASSF8,PADI2,MIER3,HNMT,ZDHHC15,HSF2,IGF1,NIM1K,TJAP1,FAM69A,INSM1,ITGA7,ITPKB,KIF2A,IPO5,KTN1,LIMS1,PAXBP1,SYTL4,NCOA7,ZNF667-AS1,MAT2A,MEIS1,MKLN1,AFF1,ZNF680,N6AMT1,SAMD14,MYO9A,NPTX2,NTRK2,CHAMP1,OPA1,PAX6,PCDH8,PCSK5,PDCD2,SLC10A4,PIK3C2A,PIK3R1,ZNF655,CCSER2,PRIMPOL,PNMA3,LRP12,LRRN3,PRKAB2,RASGEF1B,CEP41,MAPK7,CNNM2,SAMD9,WBP1L,LAMA1,CNTLN,PTCH1,PTK2,PTX3,PEX2,TUG1,FAM66C,ZNF793,SH3TC2,FAM184A,RAP1GDS1,ENOX1,OXR1,RASGRF1,RBBP6,HKR1,RGS12,RNASEL,LGI2,DCUN1D2,ALG9,PNMA8A,YY1AP1,GLDN,TCP11L1,FAM161B,RPS20,TRAPPC13,ATXN2,SCN2B,SCP2,SEC14L1,TRA2B,SH3GL3,PPM1E,KIF16B,SHC4,FBXO11,FNDC3A,FAM81A,PPP4R3A,KANSL3,PKNOX2,SEPHS1,SLC12A2,IFT122,SNAP25,SNRPN,TMCC1,RBM34,BDP1,DOK5,SP2,MYCBP2,ZC3H13,ARHGAP26,CDK19,NFASC,ITPRID2,SSTR2,NKAIN2,STAU1,CEP68,DIP2A,STXBP1,SYN2,SLC37A2,C12orf76,TACC1,KIAA1107,IQCE,WSCD1,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CYB561A3,DICER1,C18orf54,ITGB3BP,CSMD1,TPM1,CHST5,TSC1,SSBP2,ZKSCAN5,MTCH1,TBC1D15,WIPF1,RICTOR,ZIC2,ZNF24,ZNF28,ZNF154,ZSCAN26,ANKS1B,SPIRE1,SLC30A4,ZXDA,CADM2,SLC38A1,EVI5,LINC02210,ADAMTS9,PARP11,SMIM8,PHTF2,CASC15,KLHDC1,FRMD6,NETO1,RNF146,SENP7" MicroRNA hsa-miR-520f:mirSVR_lowEffct hsa-miR-520f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.72E-114 1.52E-110 1.09E-112 1.01E-111 304 1801 "ACTN1,GALNT16,ADCY5,ADCY6,RNF157,ADD1,ESYT2,FAHD2CP,SLC24A4,KCTD16,OSBPL1A,OSBPL8,SPOP,ARHGAP20,PCDH10,PDZD4,AMPD3,C6orf89,LCORL,PPP4R4,IGDCC4,SPTBN4,RGS20,NUMB,INSYN2B,EIF4G3,STX16,ATP2B2,RNF182,MYOM1,TTLL9,ADGRB3,MPDZ,BCHE,NRP2,PROM1,KSR1,DST,SYNJ1,ARHGEF7,SGCE,MYRF,CFAP410,CALB1,KALRN,SLC25A14,P2RX6,SCARB1,DGKI,DCLK1,LOC730101,SRSF11,MS4A7,B4GALT6,NRXN3,C4orf33,LY86,RCHY1,COX4I1,SMARCAL1,MYRIP,SLC35F1,FAM171B,C2CD2,ANKRD44,GDA,CRYM,SNCAIP,RGS6,ARHGEF10,OSBPL3,VAC14-AS1,PDE4DIP,CNTNAP2,FAM169A,BOC,HDAC9,RIPOR2,EARS2,RASSF2,LIN54,INTS1,DGKB,TMEM170A,BRINP1,AIF1L,DBN1,JAKMIP2,SPOCK3,WDR20,DLX1,EXOG,GRIN3A,USP3,DYNC1I1,DOCK2,DMTF1,DTNB,MAMLD1,DNAJB6,DNM1L,E2F5,EBF1,EDNRA,HIPK3,TMTC1,PHF20L1,EGFR,MRO,RGS17,CALCRL,PAN3,RCAN2,LRRC17,MTSS1L,CD320,EZH1,ZNF461,RACK1,FDFT1,FGF13,SUCO,SEMA4D,FLT1,ANKFY1,C2orf88,NBEA,ZBED3,APOPT1,ZNF605,CELF1,ST6GALNAC3,MSANTD4,GATM,ALDH1L1,ADAM28,PPARGC1A,MALT1,COPS8,GLI2,TOX3,ZNF638,DCLK2,FERMT2,PRUNE2,PCLO,GRIA2,ADAMTS13,RNF165,ZBTB49,BVES,SOX21,PSIP1,RASSF8,MAN1B1,TNFAIP8L3,BACH2,HNF4G,HSF2,ZIC5,ITPKB,KTN1,PAXBP1,HECTD2,ZNF667-AS1,MAP2,MAP4,MAT2A,MBNL1,CHIC1,LRP1B,PPM1L,MKLN1,RTL5,CCDC13,NEK1,NF1,NFE2L2,NFYA,NPTX1,PCBP3,NTRK2,OCRL,P2RY1,PAX6,DPY19L2P2,PCDH8,OLA1,ZDHHC8,SERPINI1,XRN1,GPSM2,FAM216A,PLCL1,SLC25A23,FA2H,DRAM2,CCDC144B,PPP2R5E,RASGEF1B,PRKACB,MAPK9,MAPK10,APTX,QRICH1,WDR25,PTN,ZSCAN32,PTPRB,PTPRD,NKAIN1,TUG1,OXR1,MSANTD2,PBRM1,LGI2,CCDC82,ZNF532,C12orf49,ALG9,ROBO1,ROBO2,NEK11,RPL15,ATP8B4,SALL1,SEMA6D,ATXN2,SMPD3,SUPT20H,SHC4,FHOD3,CCDC88A,SLC11A1,SLC12A2,SLC22A4,ZFP1,SMARCD3,INTS9,ANKRD36,INAVA,MBD5,SNRPN,FAM126B,PDZD2,SPTAN1,NKAIN2,ZSCAN29,CEP68,DIP2A,SYNE2,ARHGEF9,VPS13A,PLCB1,COBL,TRIM2,RPGRIP1L,SZT2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,PMS2CL,C18orf54,ZNF106,AKTIP,TIAM1,ACTR6,RIMBP2,TNS1,PIK3R5,CHST5,NR2C2,METTL3,TRIO,TRPS1,UBE2H,KLC2,RICTOR,ZFP37,TMEM237,UPF3A,SLC30A4,EMSY,CADM2,DNALI1,GDPD5,LINC02210,RNF103,HPS4,NAV3,SLC17A7,FAM47E,WNK2,ACTR3B,JMJD1C,TIGD6,NETO2,CPNE4" MicroRNA hsa-let-7a:mirSVR_lowEffct hsa-let-7a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.83E-114 2.71E-110 1.93E-112 1.78E-111 303 1793 "GALNT16,GALNT13,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,LCORL,SHROOM2,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,SLC2A11,ADAM23,ADAM15,MPDZ,CACNB4,PTBP2,CAST,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,ASIC3,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,MYEF2,DDX46,POM121,SNAP91,TMCC2,GRIN3A,DOCK2,DMTF1,DPH1,PDCD6IP,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,EBI3,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,NCALD,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,CHST15,GTF2IRD2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,LINGO1,HAS2,HLF,HMGCL,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PLCB2,TRHDE,SCHIP1,RANBP3L,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,SPIN3,KIAA0895L,TCP11L1,PTGR2,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,FOXRED1,HSPA4L,CPEB3,ST6GAL1,WDR37,BTBD3,FAM214B,SLC6A8,KDM4D,ATF7IP,CPEB4,MAST1,SMARCD3,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,TSPYL2,MCF2L2,RBM26,DDN,NFASC,POGZ,ITPRID2,SSTR2,PLCB1,SLC37A2,PDLIM2,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,HIF3A,RNF216P1,DICER1-AS1,AP4E1,ARL10,ERCC6L2,NPL,CHST5,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,ZNF28,MEIS3,FIP1L1,TRIM16L,UBE3B,KAT6A,CASC15,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-381:mirSVR_highEffct hsa-miR-381:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.94E-114 3.33E-110 2.36E-112 2.17E-111 279 1519 "ACADM,CCDC85A,ADRA1B,KCTD16,ABCD2,PCDH10,FAM135A,LRFN1,APAF1,ARNTL,ZBTB10,NUMB,EIF4G3,STX16,ATP2A2,RNF182,DOCK11,CARMIL3,BACH1,DST,NAE1,SGCE,RAB29,IL33,THSD7A,KALRN,SPAG9,ZNF501,LDB2,CDH2,MAGI1,CFL2,B4GALT6,RAB33A,RAB28,NGEF,HECTD1,ARMC8,ABI3BP,AHCTF1,ZNF521,TRIM69,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,CST3,PLXNA4,PNPLA8,BOC,DOCK4,HDAC9,ARHGAP24,PABPC5,GIT2,ARMCX2,YTHDC1,ZC3H11A,FAM107B,CHRDL1,RAB39B,DMTF1,DPP6,E2F5,EBF1,SNX29,ANKRD46,CNNM1,KLHL5,FSD1L,PHF20L1,MBNL2,KMT5B,KCTD3,EIF4G2,TENM1,PAN3,EIF1,VPS13B,EPB41,EPB41L2,LRRC17,EPHB1,CEP85L,RRAGB,DLC1,ZNF589,FGF1,POLR1B,BAIAP2,POLK,ATP5PD,FOXF2,PCYOX1,SYNCRIP,FOXO3,ATP13A4,NBEA,SMC2,UFM1,ATP6V1H,PRELID3A,STAU2,MSANTD4,GABRB3,GAD1,GALC,B4GALNT1,RAPGEF6,MTHFD2,C15orf41,KIAA1841,AHDC1,RUNDC3A,TNRC6A,MAP7D2,KCNMB4,ADGRA3,TDRKH,GPR34,PCLO,GRIA2,GRM8,KAT7,AP4S1,PSIP1,ADAMTS6,FAM222A,IRAK3,MIER3,USP51,TCEAL6,ZNF546,ZIC5,RBPJ,ZNF678,JAK2,KCND2,KIT,STXBP5,HECTD2,MAP4,MARK1,MATN2,MBNL1,LRP1B,MEIS2,SRSF12,MITF,ZNF680,MSR1,MYO9A,NEXMIF,P2RY13,NF1,CNOT4,CNTN3,PCDH8,PDE1C,ENPP2,ZNF655,FAM218A,CCSER2,XRN1,KCTD15,NLE1,PLCL1,PURG,PMP22,ING3,FA2H,KANSL1,RANBP3L,PRKACB,CEP41,MAPK4,GDPD1,SNRK,PTCH1,ANKHD1,TMEM260,PEX2,TMEM231,RAP1GDS1,OXR1,MSANTD2,REV3L,GTDC1,SLC25A36,RIC8B,PBRM1,ZNF532,GSTCD,ROBO2,RPS20,ABCA11P,SALL1,SEMA6D,SATB1,SCN7A,FNIP1,TNFRSF19,CASC3,SCAF8,KIF21A,SH3GL3,PPM1E,ARX,CHD9,R3HDM2,CNKSR2,SYBU,WDR37,PPP4R3A,EPN2,SLC6A8,ATF7IP,GKAP1,INAVA,MBD5,KIF13A,TRERF1,SP4,SPTB,IQSEC2,RBM26,DDN,LMO3,PBLD,CLSTN2,SAMSN1,SSTR2,NXT2,SEPT8,ARHGEF9,ZEB1,SYNE1,PCDHB4,FRYL,HIF3A,TEK,DICER1,ZFPM2,ZMAT3,NACC2,HEY1,ACTR6,ASXL3,BEX4,R3HDM1,KAT6B,TP53BP1,TP53BP2,TRIO,TRO,SSBP2,ZKSCAN5,SGK3,UBE3A,USP1,ZNF709,TBC1D15,VSNL1,PCDH20,ZBTB14,MICU3,LYPD6,ANKS1B,UPF3A,EMSY,MDH1B,NAV3,DNAH10,FAM13C,AMN1,PHTF2,NETO1,CPNE4,JPH3" MicroRNA hsa-miR-548n:PITA hsa-miR-548n:PITA_TOP PITA 5.99E-114 3.35E-110 2.36E-112 2.17E-111 230 1011 "FMNL2,USP31,PWWP2A,ZNF608,KLHL13,TBC1D14,OSBPL8,ZNF578,MARCH4,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NUMB,SLC4A4,ATP2A2,DOCK11,FUBP1,JAZF1,LDLRAD4,CALB1,PTBP2,LRBA,DLGAP2,NUMBL,CFL2,SRSF11,FOXN3,SOCS6,QKI,CNR1,ARMC8,AKAP5,AHCTF1,CDC42BPB,CS,SNCAIP,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,PUM1,USP6NL,HDAC4,ZFYVE16,MAML1,PABPC5,ELMSAN1,MYEF2,SACS,RAB39B,DMTF1,DPYSL2,GOLT1B,EDIL3,YAF2,MBNL2,KMT5B,EGR3,CALCRL,PAN3,ERBB2,ETV1,EYA1,TAOK3,SEC24B,FOXF2,NBEA,PDLIM5,FAM49B,STAU2,MEGF11,GABRB3,MTHFD2,ACSS1,GATM,AHDC1,TCERG1,TOX3,GNAO1,GPD2,TPPP,GRB10,GRIA2,CIT,FAM19A2,HAS2,ATXN2L,BACH2,MIER3,HMGCR,HNF4G,IGFBPL1,NEGR1,HSF2,INSM1,JAK2,KCND2,KIF2A,SMAD1,MARK1,CHIC1,LRP1B,MEF2C,MEIS1,MEIS2,KITLG,ZNF680,HNRNPM,NF1,NFE2L2,NOVA1,NRCAM,IGSF11,OCRL,CLDN11,GPR137C,PDE4B,PDE4D,GPR85,NALCN,ZNF655,XRN1,LRP12,SCHIP1,IRX1,PPP2R2C,PPP2R5E,PPP3CA,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTPN13,PTPRG,PTPRN,TTC13,PID1,ZNF493,REV3L,RIC8B,NUDT11,ZFHX4,SETD5,ROBO1,RORB,HUNK,CLIP1,RTN1,CCDC112,SATB1,TRA2B,ZFP30,PPM1E,CPEB3,MYO18A,NLGN1,WDR37,BTBD3,WDR47,FAM214B,SEPHS1,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,PDZRN3,PDZD2,SOX11,SP4,KDM4C,PEG10,ZNF423,ARHGAP26,CDK19,RBM26,CLASP2,ITPRID2,LARP4,SS18,RGL1,ADAMTS17,PLCB1,ANKRD12,CAMTA1,TAL1,FAM208A,DMXL2,SATB2,RPGRIP1L,TCF12,DICER1,ZNF106,SLC44A1,HEY1,NR2E1,RIMBP2,KAT6B,TPM1,RGMB,TRPS1,UBE3A,FLRT2,VLDLR,PCDH20,ZIC1,ZNF711,CELF4,ZBTB38,TMEM237,ZFAND5,EMSY,STOX2,PRDM10,ADAMTS9,NAV3,WNK3,PARP11,RGS7BP,FZD3,PHTF2,FRMD6" MicroRNA hsa-miR-96:mirSVR_lowEffct hsa-miR-96:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.93E-114 5.00E-110 3.50E-112 3.22E-111 299 1750 "ACADM,PWWP2A,MTA3,KCTD16,AK2,ADGRF5,SEMA6A,CEP126,PCDH10,GPRASP2,AMPD2,ZFAT,OGT,CDC42BPA,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB2,APC,RGS20,LINC00173,INSYN2B,ATP1B3,ZNF582,BACH1,KSR1,MTMR3,CACNA1G,MYRF,CALB1,ZNF501,CERS5,SCARB1,EVI5L,L3MBTL4,SRSF11,NRXN3,FBXO7,MAP4K4,SLC4A8,COX4I1,BAG4,CLOCK,ENTPD4,CRY2,SNCAIP,CNTNAP2,GREB1,RIMS2,USP6NL,CCDC144A,DOCK4,ZFYVE16,IST1,TMEM170A,SCRN1,SPOCK2,DBI,ELMO1,TIAM2,RHOBTB1,SACS,SV2B,USP3,DYNC1I1,CPEB2,SLC12A6,RCAN1,ARRDC4,DTNA,MAMLD1,AASDH,EBF1,SNX29,EDN1,EDNRB,TMTC1,APH1A,MBNL2,KMT5B,KCTD3,EIF5,ING4,RGS17,EPB41L2,IGSF6,NRN1,ARMCX1,RACK1,CEP78,PRMT5,FER,FGF13,FGFR1,AMOTL2,SUCO,ANKFY1,FLYWCH1,CAMKK2,ATP2C1,KHDRBS3,CELF1,CGREF1,SARAF,FYB1,HRASLS5,LRRC37A6P,SESN1,FREM1,PCDH17,LYVE1,TXNL4A,CRCP,TOX3,TNRC6A,AIFM3,STARD3,KDM2B,LUZP2,RAB40B,GPD2,PRUNE2,LPAR4,GPR34,CNTRL,GRM2,ZNF496,GSTM5,ADAMTS6,GUCY1B1,PADI2,SHISA6,ICA1,LRRC25,RBPJ,TJAP1,ZNF678,FAM69A,ITGAM,SLC35G1,KCNB1,KCND2,KCNN3,KIF2A,STXBP5,LAMP2,LIMS1,HECTD2,SMAD1,LYPLAL1,MBNL1,CHIC1,SRSF12,MIA2,MID1,COMMD5,MT1M,N6AMT1,NEXMIF,NCAM2,NEK1,NPTX2,NRCAM,IGSF11,CHAMP1,LOC100128398,PCDH8,CDK18,PRTG,GPR85,PFKFB2,PIK3R1,CCSER2,NLE1,EXOSC10,MAGEL2,ING3,PPP3CA,VSTM2L,PRKAB2,GRAMD1C,MASP1,CNTLN,BDNF-AS,PTK2,PTN,TMEM260,PTPRG,TMEM145,PPP2R3C,SLC25A48,RAD17,ZNF493,OXR1,RET,ERI2,GTDC1,PRIMA1,CCDC82,TMLHE,ALG9,ROBO1,ROBO2,ELP2,SPIN3,SGSM1,PTGR2,ABCA11P,RYR3,SATB1,SCN7A,SCAF8,SHC4,FNDC3A,CCDC92,FAM214B,CCDC88A,SLC12A2,SLC14A1,MTERF2,ELMO2,ATF7IP,CPEB4,CDK5RAP2,LIMCH1,KIF13A,FAIM2,SNRPN,TMCC1,FNBP1,GLT8D1,PEG10,SPTB,MCF2L2,SPART,TROVE2,SSPO,NXT2,SEPT8,DIP2A,SYNE2,COBL,TACC1,CAMTA1,ADGRL3,TCF4,SIN3B,SATB2,TCF12,PCDHGB7,SYNE1,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,LRRC8A,TMPO,TNS1,TPM2,SYNPO2,CLHC1,SGK3,PLPPR2,P2RY12,RICTOR,XPO1,XRCC4,ZBTB14,ZIC2,ZNF23,ZNF24,LYPD6,TCEAL7,EML6,ZNF189,UPF3A,SLC38A1,PRDM8,PRDM10,VPS35L,RGS7BP,ST7,MARCH8,RTN4,KAT6A,PHTF2,FXR1" MicroRNA hsa-miR-2115:mirSVR_lowEffct hsa-miR-2115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-113 6.16E-110 4.28E-112 3.94E-111 313 1918 "ASPHD1,NCKAP5,XKR4,ADCY5,GALNT13,ADORA1,ADORA2A,UNC5A,KIAA1211,MTA3,OSBPL6,ZNF578,TAOK1,USP35,ALCAM,SRPX,MARCH4,FAM135A,PDZD4,AMPD3,AMT,SUGT1P4-STRA6LP-CCDC180,APAF1,PPFIA3,SPTBN4,RGS20,ARRB2,CHRD,NUMB,SLC4A4,DPY19L3,BACH1,ADGRB3,RGS9,DNAJC27-AS1,DST,SYNJ2,RAB29,CA8,CA12,CACNA1A,CACNB4,PTBP2,VXN,CAST,NFS1,PRC1,CD86,AP4M1,ARHGEF2,DCLK1,LOC730101,CDO1,CDR1,CCPG1,CHN2,MS4A7,TPP1,SULT4A1,ARHGEF6,SLC4A8,AHCTF1,SMARCAL1,HAPLN1,CSF1R,IPCEF1,PDE4DIP,DZIP3,KIAA0040,ARHGEF4,USP6NL,KIAA0408,KATNAL2,DCAF8,ZFYVE16,IST1,DGKB,DGKG,DAPK1,AIF1L,ZBTB24,TMCC2,USP3,DOCK2,SLC25A18,ARRDC4,DTNA,EDIL3,HIPK3,FAM13A,SUGP2,C3orf18,DCTN4,LRRC17,ERBB4,KATNAL1,PTK2B,CORO2B,FCGRT,ZSCAN30,PRMT5,POLR1B,FGF13,MEX3B,IP6K2,FLT1,PSD2,TPK1,ATP2C1,ZNF605,KHDRBS3,DOT1L,MPP6,MEGF11,HRASLS5,GABRA3,GABRB3,TRAF3IP2,FAM120B,RAPGEF6,ZNF274,ADAM28,USP19,RNPS1,DBF4,GLYR1,FUT10,GPR12,GRIA2,CIT,GSTT2,PSIP1,FAM107A,RASSF8,HAS2,MAN1B1,NCKAP1L,BACH2,HLF,GABARAPL2,SYNPO,C9orf129,ZDHHC15,SHISA6,SMAP1,TJAP1,TMEM240,ZNF678,INSM1,SLC35G1,METTL21A,KCNH2,KPNA5,CYP27C1,SYTL4,SMAD1,GPR155,MAN2A2,MBP,MGAT3,SCAMP5,PPM1L,POC1B,AFF1,AFDN,HS6ST3,MYT1,CNOT4,NTRK3,OPA1,OPRL1,TREM2,PCDH9,PCSK5,GNG2,PFKFB3,NLGN3,CCSER2,XRN1,PLCL1,PRIMPOL,ANKRD16,EXOSC10,RETREG2,POU6F1,PRKAB2,PRKACB,CEP41,MAPK10,GRAMD1C,HYDIN,BCAS3,WBP1L,QRICH1,PIGG,NCR3LG1,TMEM260,ZIK1,PTPRD,EML5,PTPRN2,PTX3,SLC25A48,C1orf54,FAM184A,SUSD4,ZNF493,RASGRF2,FIGN,MRPS18A,RIC8B,PBRM1,DCUN1D2,GSTCD,MRAP2,NEK11,BAALC,GLDN,ADAL,ABCA11P,HUNK,SALL1,SEMA6D,SATB1,SCN8A,PRCD,SCP2,CASC3,GALNT10,STUM,FOXRED1,MRAS,SCAF8,FBXO11,WDR37,WDR47,KANSL3,SLC6A11,KDM4D,SLC11A1,ATF7IP,MYH15,IFT122,MAPKBP1,MBD5,FAIM2,USP33,TRERF1,BDP1,ZSWIM8,KDM4C,PEG10,ZBTB43,SPART,POGZ,ITPRID2,SSTR1,LARP4,ST5,MPRIP,NEK4,ARHGEF9,COBL,TACR1,EXOC7,TBCEL,IQCE,FBXW11,ZEB1,TPCN2,TRIM2,SYNE1,DOCK9,DICER1,ZNF106,TMEM9,TK2,PIK3R5,ZNF346,SYNPO2,STXBP4,TSC1,RPRM,PLEKHH2,VSNL1,NPDC1,RICTOR,CFAP298,KCNT2,MKRN3,LYPD6,TCEAL7,ZNF154,ZSCAN26,SPIRE1,FTSJ1,ZFAND5,DNALI1,GDPD5,TUBA1A,PDSS2,RGS7BP,DOCK8,ST7,CASC15,TRAM2-AS1,TIGD6,MSRB3,TTC7A,SOCS4,ST8SIA2,SRGAP2B,LAS1L" MicroRNA hsa-miR-200a*:mirSVR_lowEffct hsa-miR-200a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-113 1.32E-109 9.13E-112 8.41E-111 294 1698 "VWA5B2,CLK4,PWWP2A,PTCHD1,BEND6,DPY19L2P4,INTS2,HECW2,AK2,SEMA6A,ALCAM,SRPX,PCDH10,AMPH,ZFAT,CCDC146,PARG,APC,PPP4R4,TMEFF1,ARNTL,MARCH3,PCDHGB4,NUMB,INSYN2B,ATP2B2,RNF182,ATP6V1G2,ADGRB3,SEC11C,NRP2,SYNJ1,ARHGEF7,FUBP1,MTMR3,RAB29,PTBP2,VXN,CAST,CD38,DCLK1,LRRFIP1,MAGI1,CCPG1,NUMBL,NDST3,PLAA,C4orf33,ARMC8,FAM149A,COL4A5,SUMF2,TOGARAM2,ZNF521,CPS1,CLOCK,RBM39,ANKRD44,GDA,TRIM69,CS,SNCAIP,LRRC3B,CSNK1G3,VCAN,APPL1,PNPLA8,PUM1,CCDC144A,ZNF337,TMEM170A,DNAL1,MFAP3L,KLHL3,SPOCK3,CHRDL1,DMD,USP3,NR1D2,PDCD6IP,DTNA,DNAJB6,EDNRB,FCF1,KLHL5,FSD1L,YAF2,PHF20L1,SUGP2,PLEKHA1,TUBD1,ABCA8,ACSL4,CEP78,PRMT5,FER,FGF1,FGF12,FGF14,IP6K2,SYNCRIP,IQCG,SEMA4D,FLT1,SLC37A3,NELFCD,TMEM107,UFM1,PDLIM5,ATP2C1,CELF1,NSG1,MEGF10,GAD1,SIGLEC8,C15orf41,GATM,TUBGCP4,SESN1,FREM1,PCDH17,PPARGC1A,TCERG1,TOX3,GRB10,GRIA2,DIDO1,BVES,AP4S1,PSIP1,GUCY1B1,HAS2,ZDHHC15,NEGR1,SMAP1,IRF8,MSL1,ZIC5,IL6ST,JAK2,METTL21A,KCNN2,LAMP2,PAXBP1,SYTL4,MAN2A2,MAPT,MBP,TM6SF1,SHC3,MEIS1,POC1B,MSI1,ADAM22,MYO9A,RTL5,NF1,NRCAM,NTRK2,NTRK3,GPR137C,CNTN3,PAX6,PCDHGC3,PCDH8,PCDH9,PDE4B,CYTL1,FAM98B,SERPINI1,ZFYVE21,FAM216A,JAKMIP1,PURG,PMP22,STRN3,LRP12,SCHIP1,PPARA,MINDY2,TATDN3,PRKAB2,PRKACB,KLK6,VPS13C,WBP1L,SNRK,ANKHD1,ZIK1,PTPRE,ZNF615,TMEM255A,FAT4,KHDRBS2,TRIM68,RGS3,RIC8B,ZFHX4,CCDC82,EXD2,RORB,ELP2,RPL15,BAALC,ATP8B4,SGSM1,STK32B,CLIP1,TRAPPC13,DGLUCY,SEMA6D,ATXN7,PRCD,TNFRSF19,CASC3,GALNT10,ZFP30,KIF21A,PPM1E,ARX,R3HDM2,NLGN1,RADIL,CCDC88A,ELMO2,COA1,ANKRD36,SNAP25,PDZRN3,FNBP1,SOX11,NMNAT2,SAMSN1,ELOVL4,CEP68,SEPT3,SYNE2,NUDT10,PLCB1,SYPL1,SYT1,COBL,TAF9,TAL1,FAM208A,ADGRL3,TBCEL,SATB2,ZEB1,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,USP32P1,FAM200B,SIRT1,C18orf54,AKTIP,ERCC6L2,NPL,RGMB,SYNPO2,STXBP4,UCHL1,FLRT2,CCDC14,VLDLR,RBFOX3,PCDH20,ZNF711,LYPD6,ZNF154,TMEM237,CADM2,TMEM178A,FIP1L1,RGS7BP,DNAH10,FAM13C,SMIM8,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-183:mirSVR_lowEffct hsa-miR-183:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.51E-113 1.40E-109 9.62E-112 8.85E-111 298 1745 "KCNH8,CLK4,KLHL32,TMCC3,GALNT13,AXIN2,PWWP2A,ADRA1D,BEND6,INTS2,HACE1,TAOK1,ABCD2,ZFAT,LRCH2,CCDC146,PHF12,PPFIA3,CDC14B,RGS20,CADPS,N4BP2L1,DPY19L3,ATP6V0A1,ADGRB3,RGS9,NRP2,KSR1,BMPR1B,DST,SYNJ2,ARHGEF7,BTK,C5,THSD7A,HAP1,PTBP2,CBR1,LDB2,CERS5,CBFA2T2,SCARB1,CD38,C1orf52,SEPT7,MAGI1,CACNA2D2,CFL2,SOCS6,MS4A7,NDST3,MYL6B,SRP14-AS1,HECTD1,AKAP7,PCYT1B,ARMC8,AKAP6,AHCTF1,MYRIP,ZNF521,CREM,CSNK1G3,IPCEF1,GPSM1,ZSCAN23,FAM131B,DOCK4,ARHGAP32,MAML1,IST1,BRINP1,GIT2,YTHDC1,DCTN1,FBXL5,KLHL3,SPOCK3,HS3ST2,DRP2,ARRDC4,DNM1L,E2F5,EDN1,HIPK3,TMTC1,CELSR3,EGFR,MBNL2,GOLGA7,PLEKHA1,PCOLCE2,GPHN,ZNF549,ANKMY1,MRVI1,TAOK3,FGFR1,POLK,FOXF2,PDLIM5,FAM49B,ATP6V1H,ZNF605,CGREF1,ST6GALNAC3,FYN,GAD1,SIGLEC8,TUBGCP4,SULT1C4,FREM1,PPARGC1A,BRD8,TNRC6A,MSL3,MAP7D2,DCLK2,GNG4,PRUNE2,PLCD4,PLPP7,BVES,ADAMTS6,MAP4K5,UBE2QL1,PADI2,ZHX1,BACH2,HLF,ELOVL5,SYNPO,IGFBPL1,ZDHHC15,SHISA6,SMAP1,EID2B,SOWAHA,RBPJ,KCNN2,STXBP5,LIFR,SFXN5,PAXBP1,SYTL4,PIK3AP1,MAN2A2,MARK1,MATN3,ADAM11,LRP1B,KITLG,PTOV1,MXI1,MYO9A,NCAM2,NOVA1,SLC11A2,NTRK2,IGSF11,GLIPR1L2,PCDH8,PCDH9,PDCD2,PDE4D,ZNF655,PLIN1,ANKRD16,PDZRN4,TRHDE,PSAT1,SCHIP1,PPP3CA,PRKAB2,CEP41,PRKCB,EPDR1,MAPK7,RELN,PTCH1,BDNF-AS,PTK2,PTPRH,USP47,NWD1,ZNF493,MSANTD2,RDX,TRIM68,REV3L,GTDC1,FIGN,RGS3,SLC25A36,PBRM1,GSTCD,MRAP2,RPE,RPL15,BAALC,ATP8B4,ST6GALNAC6,RYR3,TRAPPC13,SAFB,SARS,SEMA6D,CSRNP3,LRFN5,SMPD3,SEC14L1,MRAS,SUPT20H,PPM1E,MYO18A,SHC4,HKDC1,FBXO11,FNDC3A,FHOD3,SEC31A,PPP4R3A,BTBD3,EPN2,ZNF334,NAPB,LGI3,SLC22A4,CPEB4,ANKRD36,INAVA,FAM126B,TRERF1,ZHX3,NMNAT2,ARHGAP26,ZSCAN29,SEPT8,PHLDB1,KLHL7,JMJD6,SYNE2,COBL,DNMBP,AGTPBP1,TBCEL,CUX2,PCDHB9,PCDHB3,SLC35G2,HIF3A,SIK3,CYB561A3,ITGB3BP,ZNF106,AKTIP,ARL10,THRA,TIAM1,HEY1,TK2,BHLHB9,FAM124A,R3HDM1,CSMD1,C9orf85,PDSS1,AMACR,STXBP4,TRPS1,TSN,TSC1,CLHC1,BCL2L13,PLPPR2,TBC1D15,ZNF711,ZNF45,LYPD6,REEP1,EML6,PCBP1-AS1,SMARCAD1,INTS3,MFF,EVI5,GDPD5,PRDM8,NAV3,SLC17A7,KCNAB1,PARP11,UBE3B,JMJD1C,MSRB3,SNX14,IFT88,GAN" MicroRNA hsa-miR-664*:mirSVR_lowEffct hsa-miR-664*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.29E-113 2.40E-109 1.63E-111 1.50E-110 300 1772 "ABR,ASPHD1,CLK4,GALNT16,BRAP,PTCHD1,ZNF608,TBC1D14,OSBPL6,CC2D2A,TAOK1,SRPX,UNC79,DPP10,EP400,LCORL,EPB41L5,PHYHD1,BCAS1,ARNTL,PLA2G4C,CADPS,ASPA,PCDHGB4,NUMB,SLC4A4,ZNF582,SLC2A11,KSR1,BMPR1B,CASTOR3,AP1M1,RAB29,DDR1,PTBP2,CAMK2G,METTL6,SLC16A4,ZBED1,DCLK1,L3MBTL4,DIS3L,CFL2,FOXN3,PLEKHB1,CPNE6,FBXO7,IGLON5,SLC35F1,SEC31B,CLOCK,HINFP,GDA,CLIP3,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,SUSD5,PDE4DIP,KIAA0040,GREB1,SEC14L5,KATNAL2,RIPOR2,ZNF337,TM9SF4,LIN54,TMEM170A,SCRN1,SPOCK2,ARMCX4,RUSC2,GUCD1,POM121,DMTF1,DTNA,MAMLD1,DNM1L,EDNRA,HIPK3,HEYL,TMTC1,SUGP2,KMT5B,AASS,EIF5,IRAK4,TENM1,TUBD1,ENPP6,DENND4A,IGSF6,ZNF549,DNAJC27,EZH1,ABCA8,FAM198B,PTK2B,DLC1,ZMYND10,GORAB,FECH,FER,GTF2IRD2,OLFM1,SPSB4,AMOTL2,PCYOX1,VTI1B,PSD2,SLC37A3,COQ5,APOPT1,CAMKK2,KHDRBS3,FYB1,FAM120B,B4GALNT1,ZNF274,MTHFD2,SRCAP,SULT1C4,GGT7,GHR,HPGDS,GLYR1,TNRC6A,MSL3,GLUL,MAP7D2,DCLK2,GNAL,GPD2,LPAR4,PCLO,PLCD4,SPACA9,ADAMTS13,CACFD1,PTPRT,ZBTB49,AP4S1,FAM107A,ADAMTS6,RASSF8,TNFAIP8L3,MIER3,SYNPO,HMGCL,ZDHHC15,MSL1,LRRCC1,INPP5B,INSM1,JAK2,SLC35G1,KCND1,KCNJ5,KIFC3,STXBP5,LIFR,LIMS1,PAXBP1,PIK3AP1,GPR155,MAP2,LYPLAL1,LRP1B,KCTD6,MID1,POC1B,COMMD5,NCF2,SLC11A2,NTRK2,NUCB2,LOC100128398,DPY19L2P2,PCDHGC3,PCDH9,CCSER2,GPSM2,PRIMPOL,MBOAT7,POU6F1,PPARA,PPM1B,TATDN3,PPP2R2C,LRRN3,PRKAB2,MTMR10,ELOVL2,ZSCAN32,ZSCAN2,TUG1,RAP1GDS1,HKR1,ZDHHC14,UBR7,MRPS18A,RIC8B,PBRM1,RNH1,PNMA8A,GSTCD,ROBO1,ROBO2,CCDC102B,RPL15,CLIP1,SALL1,MAPK12,PRCD,FNIP1,TNFRSF19,GALNT10,SH3GL3,FBXO11,ST6GAL1,FAM81A,SLC6A11,SEPHS1,CDK5RAP3,CCDC88A,SLC11A1,KBTBD4,NAPB,ELMO2,BTBD7,SMARCA4,MYH15,LIMCH1,MBD5,CABCOCO1,SNRPN,BDP1,CDK19,MCF2L2,ZC4H2,SEPT8,STAC2,KANK1,JMJD6,RHBDL3,VPS13A,ADAMTS17,SYN2,COBL,ANKRD28,SLC37A2,TACC1,TAF6,EXOC7,KIAA1107,ATMIN,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,FAM189A1,PCDHB9,SIRT1,TMEM9,TK2,TNS1,TRPS1,RUSC1,FLRT2,PLEKHH2,USP1,BCL2L13,VIPR2,PCDH20,UPF3A,CADM2,LINC02210,PRDM10,RNF103,HPS4,GAL3ST3,MPPE1,FZD3,CASC15,NLRP3,TRAM2-AS1,RNF170,IFT88,RNF146,ST8SIA2,JPH3" MicroRNA hsa-miR-4262:mirSVR_highEffct hsa-miR-4262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.28E-113 3.51E-109 2.37E-111 2.19E-110 303 1810 "KCNH8,C3orf14,NCKAP5,FMNL2,CCDC85A,BRAP,UNC5A,MTUS1,HECW2,AGT,OSBPL1A,OSBPL8,ADGRF5,C1QTNF3,FAM135A,CDC42BPA,DPP10,DDO,CDC14B,SEMA4G,MADD,NUMB,SLC4A4,RNF182,ADGRB3,BCHE,NAE1,SCAPER,JAZF1,WASF1,CA8,CALB1,KALRN,PTBP2,CAMK2G,CAST,C1orf52,LRBA,LRRFIP1,DIS3L,CFL2,RCBTB2,CHN2,NRXN3,CNTN1,AKAP7,ARMC8,FAM149A,AKAP6,AKAP5,SLC4A8,ABI3BP,TBPL1,AHCTF1,BAG4,SLC35F1,SEC31B,C2CD2,HAPLN1,SEC24C,OSBPL3,VCAN,PUM1,ZSCAN23,USP6NL,CCDC144A,CYBB,DOCK4,GAPVD1,ZFYVE16,LONRF1,DGKB,PABPC5,ELMSAN1,POM121,SPOCK3,WDR20,DYNC1I1,NR1D2,CDON,CPEB2,DPYSL2,PDCD6IP,ARRDC4,DTNB,DNAJB6,ABCC5,E2F5,EDNRB,CNNM1,KLHL5,PHF20L1,SUGP2,MBNL2,AASS,GOLGA7,KCTD3,PLEKHA1,CALCRL,USPL1,EMX2,NCALD,CDKL3,RRAGB,F5,CLVS1,RPS6KC1,TMEM132C,FDFT1,FER,BAIAP2,PRKAG2,SUCO,FLT1,SMC2,UFM1,ST6GALNAC3,NSG1,STAU2,ZNF44,CHL1,GABRG2,ZNF559,GATM,ARFIP1,GPR162,ADAM28,TCERG1,RAB40B,GPD2,CCDC184,GRB10,GRIA2,DIDO1,GRM8,CIT,UBE2QL1,ZHX1,MIER3,HLF,HMGCL,NEGR1,HSF2,HSPA1L,IRF8,ZNF181,SOWAHA,JAK2,IPO5,LIG4,PAXBP1,NCOA7,MARK1,MAT2A,MATN3,ADAM11,ZNF680,MSR1,SFR1,NF1,CNOT4,NOVA1,IGSF11,GPR137C,PCSK1,PRTG,PFKFB2,PIK3C2A,XRN1,PURG,LRP12,SCHIP1,EPB41L4B,PPARA,PPM1B,PPP2R5E,CEP41,MAPK4,EPDR1,CNNM2,BDNF-AS,MTMR10,SPDL1,C1orf109,ZNF844,PPP2R3C,QDPR,ACSS3,RASGRF2,FIGN,RFX2,SLC25A36,PBRM1,ZFHX4,TMLHE,GSTCD,ROBO2,CCDC25,PCMTD2,ARMH4,ATP8B4,LRRK2,PTGR2,CLIP1,ZNF568,RYR3,FAM192A,SEMA6D,SCN8A,FNIP1,SUPT20H,CHD9,FBXO11,FNDC3A,CNKSR2,SLA,BTBD3,EPN2,PKNOX2,CCDC88A,SLC11A1,NAPB,CPEB4,ZKSCAN3,DMRTC1,MYH15,ANKRD36,SNAP25,MBD5,CMTR2,SNRPN,PDZRN3,USP33,DOP1A,TRERF1,MYCBP2,SPP1,TEX2,ZBTB43,RBM26,LMO3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,KLHL7,PRRC2C,SYNE2,VPS13A,MTCL1,CAMTA1,TAF9,ADGRL3,TBCEL,ATMIN,SIN3B,DMXL2,ZFP90,CLASP1,SZT2,SYNE1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIK3,SIRT1,KHDC1,C18orf54,AP4E1,MTMR14,SYNPO2,RUSC1,ANKRD20A2,TTTY15,SGK3,USP1,CCDC14,ZNF781,XRCC4,ZBTB14,ZIC2,MICU3,ZNF74,NDRG4,SPIRE1,EMSY,LINC02210,PRDM8,HPS4,SEMA3B,MDH1B,PARP11,PHTF2,IFT88,CPNE4,LAS1L" MicroRNA hsa-miR-764:mirSVR_lowEffct hsa-miR-764:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-112 6.50E-109 4.36E-111 4.01E-110 310 1898 "DGCR6,ABHD6,SYS1,KLHL32,TMEM132B,ADORA1,RNF150,AP2A2,RTL9,OSBPL1A,OSBPL8,CC2D2A,TAOK1,ALCAM,PCDH10,AMPD2,ANK2,SUGT1P4-STRA6LP-CCDC180,UPRT,APOC2,SPTBN4,DNAH17,TMEM108,EIF4G3,ATP1B3,DPY19L3,RIPK1,CARMIL3,ADAM15,LINC00847,LDHD,NAE1,MTMR2,GPC2,RAB29,WASF1,CA4,CA8,DDR1,CALB2,CAPN3,ISPD,USP2,P2RX6,CD86,CBFA2T2,ENTPD6,DGKI,LRRFIP1,CRLF1,NUMBL,ASIC3,RAB33A,NRXN3,PPT2,CLCN3,TPP1,FBXO7,FAM189A2,SULT4A1,SRP14-AS1,CNTFR,ARMC8,FAM149A,C2CD2,HAPLN1,CLIP3,CS,CSF1,CSF1R,SEC24C,CSNK1E,SIPA1L1,SOCS5,PDE4DIP,PLXNA4,SLITRK5,KIAA0040,APPL1,CTH,GREB1,RIMS2,BOC,DOCK4,RIPOR2,ARHGAP24,LIN54,DGKB,IP6K1,GIT2,ARMCX4,ZNF804A,HEPH,RUSC2,LYPD1,GUCD1,POM121,SV2B,WDR20,RAB39B,DNM1,HS3ST2,RPS6KL1,SLC29A4,NR1D2,DPH1,SNX29,PHC2,APH1A,EBI3,EGFR,MBNL2,RASA4,VPS13B,EPHB1,RABEPK,STX2,DENND4A,IGSF6,CDKL3,DNAJC27,MRVI1,F8,DLC1,RACK1,FCGRT,ZSCAN30,FGF11,PRKAG2,MEX3B,HPCAL4,FLT1,NELFCD,WDR83,NBEA,POMT1,APOPT1,CAMKK2,CGREF1,NSG1,DLL3,STAU2,TVP23A,GAA,LRRC37A6P,ALDH1L1,ADAM28,FREM1,TTBK1,COPS8,GLUL,LILRB4,TDRKH,FUT10,LILRA2,GPER1,GRB10,GRIA2,ADAMTS13,COQ10A,GSTM5,SOX21,FRMD5,ATXN2L,AGBL5,CPT1C,KNDC1,TJAP1,NME9,ITPKB,KCND2,KCNN2,KIF2A,A1BG-AS1,MAP2,MAP4,MATN3,MBP,CHIC1,MID1,MMP16,GIT1,COMMD5,TAGLN3,LYRM9,MYO7A,NEXMIF,CNOT4,NTRK2,NUCB2,OCRL,OGG1,OXTR,P2RX7,ZNF827,PAX6,DPY19L2P2,PKM,FXYD1,ZNF426,MTRF1L,LRP12,EXOSC10,PKIA,MAPK4,MAPK7,KLK6,PSD,PIGG,PTPRE,ZSCAN2,QDPR,TMEM255A,CCDC40,RASGRF2,RBBP8,KHDRBS2,MSANTD2,RGS4,TMLHE,CYB561D1,NEK11,RPL15,SPIN3,GLDN,SGSM1,HUNK,HSD11B1L,ZNF568,TRAPPC13,S100B,SEMA6D,SCP2,TNFRSF19,SMPD3,GALNT10,RASA3,SGK1,SHMT2,ST6GAL1,NLGN1,EPN2,PKNOX2,SLC6A8,SEPHS1,CDK5RAP3,SLC9A5,SLC11A1,LGI3,CDK5RAP2,ANKRD36,SNCA,MYO16,TSNAXIP1,FNBP1,SP2,ZSWIM8,KDM4C,ERC1,SPTB,CLASP2,LARP4,SSPO,DIP2A,SEPT3,NSFL1C,VPS13A,SYN2,SLC37A2,CAMTA1,PDLIM2,ALG1,ADGRL3,SLC19A3,HIF3A,DICER1,ZNF34,TK2,TPM1,C9orf85,WBP2,TRO,ANKRD20A2,TSC1,RPL7L1,OSBP2,MTCH1,RICTOR,GUSBP1,ZBTB14,ZNF138,ZNF154,REEP1,SPIRE1,MEIS3,UPF3A,GDPD5,PRDM8,PRDM10,RNF103,HPS4,FIP1L1,PDSS2,RGS7BP,DOCK8,FAM219B,TIGD6,FXR1,IFT88,JPH3" MicroRNA hsa-miR-10a*:mirSVR_lowEffct hsa-miR-10a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-112 7.57E-109 5.05E-111 4.65E-110 298 1756 "KDM5D,USP31,PTCHD1,ADRB2,INTS2,PCDH19,ALCAM,PCDH10,FAM135A,LRCH2,MAP4K3,PARG,APAF1,MAGEE2,PPP4R4,TMEFF1,ARNTL,RGS20,STK33,NCOA1,EIF4G3,DPY19L3,BACH1,SEC11C,SYNJ1,NAE1,BTK,WASF1,KALRN,CAST,ZNF501,LDB2,USP2,CDH2,L3MBTL4,MAGI1,CCPG1,CLGN,SRSF11,SOCS6,NRXN3,ABCG2,QKI,CNTFR,ARMC8,AKAP6,COL4A5,COL9A3,RCHY1,GAL3ST1,ZNF521,ZFP28,ANKRD44,ARHGEF10,VCAN,PHACTR3,DZIP3,APPL1,PNPLA8,RIMS2,ZSCAN23,RUBCN,HDAC9,KIF26A,TMEM170A,PITPNC1,ARMCX2,ELMO1,C2CD2L,DDX46,DYNC1I1,DTNA,DNM1L,AASDH,WDPCP,FSD1L,PHF20L1,APH1A,EGFR,EIF4G2,TMEM35A,STARD3NL,DENND4A,ETV1,ADGRV1,ARMCX1,ABCA8,TAOK3,CEP78,FDFT1,FER,MED12L,GTF2IRD2,SUCO,SCARA3,EFCAB2,APOPT1,KHDRBS3,ST6GALNAC3,STAU2,DOT1L,MPP6,GALNT15,GABRG2,FAM120B,ZNF234,IQGAP2,MTHFD2,C15orf41,GATM,MSTN,ADAM28,MMADHC,GGT7,TNRC6A,STARD3,ZNF638,KDM2B,RAB40B,GNAO1,WDFY3-AS2,STON1,GPER1,FAM19A2,ZBTB49,PSIP1,ADAMTS6,GUCY1B1,MAP4K5,IRAK3,FRMD5,CELF5,LRRCC1,SCIN,LRRTM1,SLC35G1,IPO5,LAMP2,PAXBP1,MAP4,MAT2A,MBD1,MBNL1,TM6SF1,LRP1B,KITLG,POC1B,AFDN,ZNF680,ADAM22,MYT1,HNRNPM,NCAM2,NEK1,NELL2,NF1,NOVA1,DNHD1,NRCAM,SMIM11A,P2RY1,CNTN3,PAX6,PCSK1,PDE4B,ABCB1,CCSER2,SNX10,KCTD15,GPSM2,PURG,MAPKAP1,PSAT1,SCHIP1,EPB41L4B,KANSL1,RANBP3L,PKIA,KLK6,CNNM2,SNRK,PTCH1,ZSCAN32,PTPN13,PTPRD,PTPRN2,TTC13,CEP97,RAD17,FAT4,RAP1GDS1,ZCWPW1,RBBP6,KHDRBS2,REV3L,GTDC1,RFX3,SLC25A36,PBRM1,ZFHX4,CARF,RORB,ADAL,ZNF354C,ZNF568,NCBP3,SAFB,ATXN7,SCAF8,ZFP30,KIF21A,SH3GL3,KIF16B,FBXO11,FNDC3A,NLGN1,WDR37,CCDC88A,BTBD7,CPEB4,SNAP25,CMTR2,ZNF415,SNRPN,KDM3A,ZC3H13,MCF2L2,RBM26,SPART,CLASP2,MESP1,SAMSN1,SS18,STAU1,NEK4,KLHL7,NECAB1,PRRC2C,VPS13A,PLCB1,TACC1,PJA1,MCF2L,KIAA1107,FBXW11,TCEA1,SATB2,DOCK9,TNS2,PCDHA5,RNF175,SIK3,DNAH7,SIRT1,ZFPM2,ITGB3BP,AKTIP,CSMD1,PIK3R5,TRIO,TTC3,PRR18,CLHC1,HIRA,RPRM,UBE2H,UGT8,USP1,TOM1L2,VSNL1,WIPF1,GUSBP1,XPO1,ZNF711,TRIM9,CELF4,EML6,ANKS1B,MFF,CADM2,PRTFDC1,SLC38A1,LINC02210,RNF103,ADAMTS9,MDH1B,FIP1L1,WNK3,PDSS2,DNAH10,FAM13C,FZD3,UBE3B,PHTF2,CASC15,TIGD6,IFT88,SOCS4" MicroRNA hsa-miR-496:mirSVR_lowEffct hsa-miR-496:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.91E-112 1.07E-108 7.06E-111 6.50E-110 286 1619 "RALGAPA1,CLK4,ADD1,USP31,PWWP2A,SLC24A4,MTUS1,KLHL13,PCDH19,HACE1,OSBPL8,CC2D2A,ALCAM,ARHGAP20,FAM135A,ZNF687,CCDC146,MYH7B,MAGEE2,DDO,PPP4R4,PCDHGB4,DPY19L3,RIPK1,ADGRB3,LINC00847,FUBP1,NAE1,BTK,PTBP2,CAST,RUNX1T1,MAGI1,NPIPA1,SRSF11,FOXN3,CNOT8,LHX2,C4orf33,HECTD1,PCYT1B,RCHY1,NRG2,IGDCC3,RBM39,NCOR2,TRIM69,IPCEF1,PLXNA4,FAM169A,KIAA0040,PLCXD3,RIMS2,DOCK4,HDAC4,ZFYVE16,CENPL,LONRF1,TBC1D5,MATR3,DAPK1,BRINP1,YTHDC1,DGCR5,SNAP91,MTX3,WDR20,SEC16A,USP3,DPYSL2,RCAN1,E2F5,AASDH,EDNRB,PHC2,SEMA3D,PHF20L1,MBNL2,GOLGA7,EIF4G2,PLEKHA1,PCOLCE2,USPL1,EPB41L2,RABEPK,DENND4A,IGSF6,CEP85L,ETV1,EZH1,ABCA8,FAM198B,ACSL4,ST3GAL6,CEP78,FKTN,FGF12,FGF14,POLK,MEX3B,FOXF2,ATP13A4,FAM49B,CSPG5,STAU2,MEGF10,GABRG1,GABRG2,GALC,ERAP1,MTHFD2,GCNT2,MSTN,WASHC2A,AHDC1,GFRA2,PPARGC1A,ZNF638,MAP7D2,GNAL,FERMT2,LPAR4,GPER1,PCLO,RNF165,ADAMTS6,UBE2QL1,MIER3,HNF4G,ZNF491,ZDHHC15,TCEAL6,SMAP1,IRF8,NKD1,IL6ST,IBA57,ZNF678,KCND2,KCNN3,KHK,KTN1,PAXBP1,HECTD2,MAP4,MARK1,MARK3,LRP1B,MEIS2,KITLG,ZNF680,SAMD5,MYO7A,MYO9A,NEK1,NF1,ALDH1L2,CNOT4,NUCB2,CLDN11,PCDHGC3,PDE4D,ENPP2,PFKFB3,ABCB1,PCDH18,PPM1B,PPP2R2B,PPP3CA,RANBP3L,PRKAB2,MAPK9,MASP1,RELN,SNRK,CNTLN,ANKHD1,NCR3LG1,BDNF-AS,PTN,PTX3,TTC13,PID1,ZCWPW1,RADX,KHDRBS2,REV3L,UBR7,RGS4,SLC25A36,LGI2,ZNF532,RPL15,ZC3H14,ZNF568,CCDC112,TRAPPC13,DGLUCY,SALL1,SMPD3,SEC14L1,COPZ1,RASA3,KIF16B,NLGN1,PPP4R3A,DHX30,ARHGEF40,CCDC88A,MYH15,INAVA,SNCA,KIF13A,FAM126B,RBM34,USP33,FNBP1,KDM3A,ZHX3,HECW1,MYCBP2,SPP1,TEX2,RBM26,LMO3,POGZ,ZC4H2,NKAIN2,STAU1,CEP68,ADHFE1,ZC3H4,TAF9,SATB2,ZEB1,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ZFPM2,ITGB3BP,ARL10,TIAM1,TMPO,FAM124A,CSMD1,SYNPO2,METTL3,AMACR,TRO,TRPS1,TTC3,SGK3,UBE2H,UGT8,PLEKHH2,CLDND1,XRCC4,ZNF708,ZNF19,MICU3,ZNF74,ZNF138,ZSCAN26,KCNAB1,WNK3,EPM2A,RGS7BP,DNAH10,DOCK8,ST7,FBXO36,ADAMTSL3,TIGD6,ZDHHC20,IFT88,RNF146,CPNE4" MicroRNA hsa-miR-20a*:mirSVR_highEffct hsa-miR-20a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.16E-112 1.21E-108 7.95E-111 7.32E-110 277 1518 "ACADM,FMNL2,BEND6,DPY19L2P4,ZNF608,INTS2,HECW2,OSBPL1A,TXNDC16,AMPD3,OGT,CDC42BPA,LRCH2,PHF12,APC,PHYHD1,AQP6,SFMBT2,PPP4R4,ZFYVE28,LINC00173,PDE8B,EIF4G3,SLC2A11,MYOM1,DOCK11,ADAM23,BACH1,ADGRB3,MPDZ,NRP2,CA8,KALRN,PRC1,KRIT1,METTL6,MTMR7,CBFA2T2,ZBED1,LRRFIP1,CFL2,CHN2,NDST3,NRXN3,FAM189A2,IQCK,AKAP6,SLC4A8,RCHY1,CLOCK,RBM39,ANKRD44,CSF1R,RGS6,CSF2RA,CSNK1G3,SOCS5,VAC14-AS1,PHF14,ZSCAN23,DCAF4,USP6NL,CYBB,HDAC9,RIPOR2,MATR3,DGKB,DAPK1,GIT2,SPATA2,MYEF2,ALKBH8,CHRDL1,EXOG,NR1D2,CPEB2,PDCD6IP,ECM2,MAMLD1,EBF1,HEYL,OPTN,KMT5B,ING4,DCTN4,GPHN,NCALD,CDKL3,EXTL2,FAM198B,RPS6KC1,ACSL4,FCGR1A,CHST15,SLC9B2,FER,FGF11,SUCO,SEC23B,IQCG,ANKFY1,NOP56,SMC2,APOPT1,PDLIM5,FAM49B,ATP6V1H,CELF1,AP4B1,GABRG1,GALC,ZNF234,SIGLEC8,SEPT9,MSTN,ADAM28,DHRS4,ADGRA3,GSN,RASSF8,HAS2,FRMD3,BACH2,MIER3,ZNF491,SHISA6,SOWAHA,RBPJ,KCND2,KLHL23,KIF5A,LAMP2,HECTD2,NCOA7,MAT2A,MATN2,MBNL1,TM6SF1,AFDN,MMP16,ZNF680,NRBP2,ZNF92,MYO9A,NELL2,NF1,CNOT4,NRCAM,NUCB2,SETD4,CNTN3,DPY19L2P2,GPR85,NALCN,PIK3C2A,ZNF655,STRN3,LRP12,SH3KBP1,PPM1B,PPP3CA,NKAIN4,PKIA,MAPK10,GRAMD1C,MASP1,SAMD9,APTX,PIGG,CNTLN,PTCH1,TMEM260,PTPN13,PTPRE,ACSM5,TTC13,ZNF615,USP47,FAM66C,RAP1GDS1,ZNF493,RASGRF2,RADX,RET,REV3L,GTDC1,FIGN,RFX3,RGS12,RIC8B,CCDC82,TMLHE,C12orf49,CARF,ROBO1,ATP8B4,ABCA11P,ATAT1,ZNF568,RYR3,NCBP3,SEMA6D,SATB1,ATXN7,SCN8A,ZFP30,CPEB3,MYO18A,SHC4,FBXO11,BTBD3,WDR47,TET1,CPEB4,CDK5RAP2,ANKRD36,KIF13A,SNRPN,KDM4C,RBM26,LHPP,ZNF302,SSTR2,SEPT8,CEP68,RGL1,VPS13A,PJA1,MCF2L,TAF9,KIAA1107,ATMIN,TCF4,RPGRIP1L,SYNE1,SLC35G2,SIK3,DNAH7,SIRT1,C18orf54,AP4E1,CDH22,ASXL3,ERCC6L2,R3HDM1,KAT6B,SYNPO2,RUNDC3B,CA14,UBE3A,UGT8,VSNL1,RICTOR,ZBTB14,ZNF708,MICU3,ZNF45,ZBTB38,ZNF154,FTSJ1,SMARCAD1,DHX33,CADM2,PRTFDC1,TMEM178A,HPS4,NAV3,WNK2,PDSS2,HNRNPA3,TIGD6,RNF170,MSRB3,KLHDC1,FXR1,IFT88,GAN" MicroRNA hsa-miR-127-5p:mirSVR_lowEffct hsa-miR-127-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.29E-112 1.84E-108 1.20E-110 1.11E-109 305 1845 "RALGAPA1,NCKAP5,KDM5D,GALNT13,UNC5A,KIAA1211,ESYT2,SLC24A4,INTS2,HECW2,KLHL13,WDR35,TXNDC16,SPOP,ALCAM,AMPD2,ZFAT,APC,UPRT,TNRC6C,PPFIA3,PPP4R4,RGS20,CDK13,NUMB,TMEM108,SLC4A4,RIPK1,ADAM15,BACH1,ADGRB3,MPDZ,GPR146,KSR1,DST,SYNJ2,ARHGEF7,FUBP1,CASTOR3,MYRF,BAIAP3,CA4,CACNA1A,SLC25A14,CAST,SPAG9,NFS1,ARHGEF25,SEPT7,CDH2,LARGE1,SLIT2,LHX2,QKI,MAP4K4,CNTN1,SUMF2,LETMD1,ABI3BP,MYRIP,NRG2,CRMP1,ANKRD44,GDA,SEC24C,ARHGEF10,IPCEF1,RIMS4,VAC14-AS1,PDE4DIP,CNTNAP2,PLXNA4,DZIP3,PPP1R16B,APPL1,GREB1,RIMS2,DCAF4,RUBCN,CCDC144A,CYBB,KIAA0408,GAPVD1,RASSF2,LIN54,MATR3,DGKB,ELMSAN1,DCTN1,ZBTB24,MFAP3L,KIAA0319,KLHL3,DMD,DNM1,SLC29A4,DOCK2,DPYSL2,ECM2,TOM1,E2F5,E2F6,EBF1,EDIL3,WDPCP,EDN3,EGFR,MBNL2,IRAK4,PLEKHA1,RGS17,ELN,USPL1,EPB41,GPHN,STX2,NCALD,ETV1,DNAJC27,GMPR2,CLVS1,SH3YL1,TUBA1B,PRMT5,ZNF589,SLC9B2,FGF1,MEX3B,HPCAL4,SYNCRIP,NELFCD,EFCAB2,TMEM107,RASL10A,CELF1,HHIPL1,ABLIM2,GALNT15,GABRG2,GHDC,SEPT9,GATM,GCNT2,ADAM28,PCDH17,GGT7,PPARGC1A,HPGDS,SPIN1,MAP7D2,LUZP2,DCLK2,GNAL,GPD1,GRIA2,ADAMTS13,LINC01089,GSTM5,GSTT2,ZBTB49,FAM107A,SLC2A6,ATXN2L,GABARAPL2,SYNPO,HNMT,SOWAHA,RBPJ,KIF5A,KIT,CYP27C1,MAN2A2,MAPT,MBNL1,MBP,TM6SF1,MEIS1,PPM1L,POC1B,MN1,ADAM22,HS6ST3,MXI1,MYO9A,ZC3H12B,TBC1D25,CHAMP1,CLDN11,CNTN3,PDE4D,ENPP2,SLC10A4,PFKFB2,PLCL1,PCDH18,SCHIP1,SH3KBP1,PPM1B,PPP1R1A,LRRN3,PRKCB,MAPK10,CYBC1,PTCH1,BDNF-AS,MTMR10,ELOVL2,SPDL1,PTPRD,ZSCAN2,ZNF793,RASGRF1,RBBP6,KHDRBS2,ZDHHC14,RDX,TRIM68,FIGN,RGS3,PRIMA1,NUDT11,ZFHX4,TMLHE,EXD2,KLHDC8A,CARF,ROBO1,CCDC25,YY1AP1,PCMTD2,CCDC102B,SNX22,NEK11,MCMBP,ADAL,MEG3,CLIP1,DGLUCY,ATXN2,SCP2,TRA2B,HSPA4L,PPM1E,AMBRA1,DZIP1,SLA,PREX2,PKNOX2,SLC6A11,SLC8A1,CDK5RAP3,ELMO2,LGI3,MAST1,MBD5,SNRPN,FAM126B,USP33,PDZD2,RBM26,NFASC,TROVE2,NXT2,NECAB1,NUDT10,SYT1,FBXW11,NEU4,ZFP90,ZEB1,TPCN2,GPRIN3,CYB561A3,RNF216P1,C18orf54,AP4E1,GPR161,TK2,ASXL3,TPM1,STXBP4,ZKSCAN5,CLHC1,UCHL1,LINC00689,FLRT2,TBC1D15,SLC47A2,ZNF28,TRIM9,CELF4,ZNF154,AMZ1,ZNF213,STOX2,ADAMTS9,URM1,FAM47E,DOCK8,HNRNPA3,ADAMTSL3,TRAM2-AS1,RNF170,KLHDC1,FXR1" MicroRNA hsa-miR-20b:mirSVR_highEffct hsa-miR-20b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.89E-112 2.18E-108 1.41E-110 1.30E-109 285 1612 "KCNH8,NCKAP5,SLC24A4,HACE1,ABCD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,TNRC6C,CASK,LINC00173,STK33,RASL11B,SLC4A4,EIF4G3,ATP1B3,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,CBR1,USP6,C1orf52,TIGD7,CFL2,MS4A7,B4GALT6,TAOK2,EPS15L1,ABCG2,C4orf33,COL4A5,AKAP5,SLC4A8,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,FAM78B,DNAJB6,DNM1L,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,NSG1,MSANTD4,GABBR1,B4GALNT1,ERAP1,DISC1,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,ATP2B1-AS1,CIT,AP4S1,RABL2A,IRAK3,HAS2,MSL1,METTL21A,KCNJ16,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,NCOA7,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NCF2,SFR1,NELL2,NF1,CNOT4,NTRK3,OCRL,OGG1,OPA1,GPR137C,CNTN3,ETFRF1,PDE4D,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PSAT1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,TMEM260,PTPN13,PTPRD,PTPRO,CEP97,TMEM255A,USP47,FAT4,OXR1,RASGRF2,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,ATXN2,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,TSC1,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-18b:mirSVR_lowEffct hsa-miR-18b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-112 2.73E-108 1.76E-110 1.62E-109 284 1602 "KLHL32,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,AXIN2,ESYT2,DPY19L2P4,RTL9,HACE1,KIAA1324,OSBPL8,AK2,SEMA6A,USP35,FAM135A,DPP10,ANK2,LCORL,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,UPRT,NT5C3B,APOC2,AQP6,CDK13,NUMB,CHID1,EIF4G3,DPY19L3,ADGRB2,LINC00847,BBS2,SEC11C,DST,SYNJ1,MYRF,CACNB4,PTBP2,CAMK2G,HIP1R,RHBDL1,NFS1,LDB2,CD86,MAGI1,CCPG1,TAOK2,NRXN3,TPP1,DGCR9,VAX2,SULT4A1,CNR1,ABI3BP,FAM171B,CLOCK,CRY2,ANKRD44,SNCAIP,CSF1R,SEC24C,CSNK1E,SIPA1L1,SLITRK5,CTH,MYADM,DCAF8,TBC1D5,KIAA0586,GIT2,ARMCX4,ZNF804A,DGCR5,MYEF2,TMEM130,DNM1,DYNC1I1,SLC12A6,ABCC5,E2F5,EDNRB,PHC2,EGFR,MBNL2,KMT5B,TNK2,TMEM35A,MFSD10,GPHN,ERBB2,DENND4A,ANKMY1,SIRPB1,CHST15,FKTN,ZSCAN30,ZNF589,GORAB,FGFR3,UBE2E3,SYNCRIP,FLT1,PSD2,EFCAB2,NBEA,SMC2,UFM1,STAMBP,CAMKK2,CELF1,HHIPL1,TPPP3,GABRB3,GABRG2,IP6K3,ZNF559,DISC1,LRRC37A6P,KIAA1841,ALDH1L1,ZNF276,COPS8,SPIN1,WDFY3-AS2,ADGRA3,GPD1,TDRKH,GRIA2,DIDO1,PLCD4,ADAMTS13,RNF165,PACSIN2,ATXN2L,VSIG4,ELOVL5,HMGCL,AGFG1,DHX35,MSL1,FAM95B1,RBPJ,LRRCC1,METTL21A,KCND2,KCNN2,KIT,IPO5,STXBP5,KTN1,SYTL4,HECTD2,ZNF667-AS1,MAP4,MARK1,MAT2A,ADAM11,MEF2C,MEIS1,TAGLN3,MYO9A,NOVA1,NTRK2,NTRK3,OGG1,LOC100128398,OPRL1,PAX6,DPY19L2P2,PCDH9,CDK18,SLC10A4,GNG2,PFKFB2,PFKFB4,PCDH18,PLXNB1,ANKRD16,EPB41L4B,POU6F1,PPM1B,PPP2R5E,EPDR1,BCAS3,WBP1L,NCR3LG1,BDNF-AS,TMEM260,ZSCAN32,PTPN13,PTPRE,PTPRG,PTPRO,PID1,CCDC40,SH3TC2,ZCWPW1,REV3L,RGS4,RGS12,LGI2,ALG9,GSTCD,ROBO1,ELP2,PCMTD2,EPHA10,BAALC,ADAL,TCP11L1,LRRK2,KCNIP1,CLIP1,TRAPPC13,FAM192A,SAFB,SEMA6D,SCP2,SMPD3,SCAF8,FERMT1,FNDC3A,ABLIM3,SEPHS1,CCDC88A,ARFGAP1,MAST1,CDK5RAP2,IFT122,ANKRD36,SNCA,SNRPN,MYO16,KDM4B,FNBP1,ZSWIM8,CLASP2,POGZ,MESP1,SSTR2,SSPO,ZSCAN29,NSFL1C,NECAB1,ARC,SYN2,SYPL1,DNMBP,KLHL4,TRIM2,FAM189A1,PCDHB4,USP32P1,GPRIN3,DICER1,ZFPM2,ERCC6L2,TMPO,R3HDM1,CSMD1,TNS1,WBP2,CHST5,UBE2H,OSBP2,ZNF709,VLDLR,ZIC2,ZNF540,ZNF154,REEP1,POLR3H,TFIP11,RNF103,GAL3ST3,PARP11,PDSS2,ST7,UBE3B,TRAM2-AS1" MicroRNA hsa-miR-376a:mirSVR_lowEffct hsa-miR-376a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.36E-112 3.00E-108 1.92E-110 1.77E-109 285 1614 "XKR4,GALNT13,RNF150,ZNF608,AGT,RTL9,KIAA1324,CC2D2A,C1QTNF1,ALCAM,FAM135A,GPRASP2,TRMT9B,PITPNM2,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,MAGEE2,USP37,ZBTB10,NUMB,TMEM108,SLC4A4,N4BP2L1,DPY19L3,CFLAR,BMPR1B,DST,SYNJ1,MTMR2,KALRN,PTBP2,SPAG9,NFS1,ENTPD6,CDH2,DCLK1,ZMYM4,LRRFIP1,LOC730101,CHN2,CHRNA4,B4GALT6,RAB33A,CLCN3,SRP14-AS1,HECTD1,FHL5,CNN3,ARMC8,SUMF2,RTTN,ZNF521,NRG2,PREPL,CREM,NCOR1,CLIP3,CSF2RA,ARHGEF10,CNTNAP2,DZIP3,PHF14,CTH,PUM1,FAM131B,DCAF8,ZNF337,PABPC5,DNAL1,JAKMIP2,DDX46,SPOCK3,DLX1,GRIN3A,DMD,NR1D2,DOCK2,ACOT8,CNNM1,SEMA3D,FRY,YAF2,FAM13A,KMT5B,AASS,EIF4G2,EIF5,PLEKHA1,RGS17,CALCRL,VPS13B,LRRC17,DENND4A,EXTL2,F5,SCML2,ST3GAL6,ZSCAN30,SEC24B,FER,FGF1,FGF14,FGFR1,SUCO,UBE2E3,PCYOX1,FLT1,NOP56,UFM1,PDLIM5,MSANTD4,MEGF10,CHL1,GABRG1,GABRG2,IQGAP2,DISC1,KIAA1841,MSTN,PCDH17,PPARGC1A,GLI2,MSL3,LUZP2,GPD2,LILRA2,GPR12,GRIA2,SERP2,ATE1,AP4S1,LINGO1,PSIP1,MAP4K5,NEGR1,NKD1,RBPJ,LRRCC1,IL6ST,INPP5B,JAK2,SLC35G1,LIMS1,MATN2,MBP,CHIC1,MEIS2,MEST,KCTD6,AFDN,ZNF680,SAMD5,BLOC1S2,MSR1,ZNF92,NEXMIF,ZC3H12B,NFE2L2,NPTX1,NTRK2,GPR137C,PAX6,PCDH8,PCSK5,ENPP2,NALCN,PIK3C2A,PIK3R1,ZFYVE21,XRN1,PLCL1,PLIN1,PURG,PDZRN4,STRN3,RETREG2,PPARA,RASGEF1B,PRKCB,DIRAS2,BCAS3,PTCH1,ANKHD1,PTN,TUG1,TMEM255A,SH3TC2,RAP1GDS1,ENOX1,OXR1,MSANTD2,REV3L,RFX3,RGS12,RIC8B,RNASEL,LGI2,ARMC5,CARF,CCDC102B,FBXW7,ZC3H14,ADAL,MEG3,HUNK,ATAT1,ZNF354C,CCDC112,DGLUCY,SATB1,LRFN5,SCP2,FNIP1,KIF21A,SH3GL3,PPM1E,FNDC3A,R3HDM2,NLGN1,DZIP1,BTBD3,ZNF334,CPEB4,ZFP1,SMARCC2,ANKRD36,SNRPN,FAM126B,TRERF1,CLASP2,TROVE2,CEP68,TTBK2,ADHFE1,KANK1,SEPT3,STXBP1,KLHL7,PLCB1,SYN2,SYPL1,TACC1,PDLIM2,MGRN1,SATB2,TPCN2,RPGRIP1L,PUM2,USP32P1,SLC35G2,DICER1-AS1,ITGB3BP,TP53BP1,NPL,STXBP4,TSN,ZKSCAN5,SGK3,FAM155A,UBE2H,PLEKHH2,XPO1,XRCC4,MICU3,ZNF28,ZNF32,AGMO,TMEM237,ZNF177,EML6,ZSCAN26,INTS3,SLC30A4,CADM2,EVI5,STOX2,FAM47E,FAM13C,AMN1,DOCK8,RSPRY1,RNF170,KLHDC1,NETO1" MicroRNA hsa-miR-556-3p:mirSVR_lowEffct hsa-miR-556-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.91E-112 3.31E-108 2.11E-110 1.94E-109 304 1837 "KDM5D,XKR4,BEND6,INTS2,HECW2,KCTD16,WDR35,C1QTNF3,ALCAM,ARHGAP20,MARCH4,ZNF687,LRCH2,LCORL,MAP4K3,APBB2,APC,UPRT,LGR5,IGDCC4,TMEFF1,NCOA1,ATP1B3,ZNF582,DOCK11,SCAPER,MTMR2,GPC2,CALB1,PTBP2,LDB2,MTMR7,SLC16A4,SCARB1,ENTPD2,SEPT7,LRRFIP1,MAGI1,DLGAP1,TIGD7,CCPG1,CFL2,SRSF11,MS4A7,RAB28,NRXN3,PLAA,CNN3,ARMC8,AKAP6,FAM171B,SEC31B,CLOCK,SNCAIP,CSNK1E,OSBPL3,PDE4DIP,PHF14,PLCXD3,CTH,ARHGEF4,ZSCAN23,GAPVD1,KIAA0586,GIT2,YTHDC1,HEPH,TIAM2,SACS,SPOCK3,USP3,NR1D2,CPEB2,DNM1L,GOLT1B,E2F6,EDIL3,WDPCP,EDNRB,TMTC1,FRY,YAF2,FAM13A,EGR3,ASB3,EIF4G2,TENM1,RGS17,STARD3NL,EMX2,VPS13B,EPB41L2,COQ7,LRRC17,SRRM1,MRPL37,APC2,ETV1,DNAJC27,ADGRV1,EYA1,F5,FAM198B,DLC1,FCGR1A,ZNF589,SLC9B2,MEX3B,SEC23B,SYNCRIP,RGPD5,NELFCD,JKAMP,NBEA,TMEM107,SMC2,PDLIM5,ZNF605,SARAF,MEGF10,GABRB3,GABRG1,B4GALNT1,ZNF274,GATM,SRCAP,SESN1,MALT1,LYVE1,ZNF276,GLI2,TOX3,LUZP2,GNAL,LPAR4,KAT7,BVES,SOX21,PSIP1,RNFT2,ZDHHC15,SHISA6,SOWAHA,RBPJ,LRRCC1,IL12A,FAM69A,METTL21A,KCNH2,KCNJ16,IPO5,MBP,CHIC1,LRP1B,KCTD6,KITLG,XRRA1,MSR1,ZNF92,MYCN,NDP,SFR1,NF1,NFYA,NNAT,CNOT4,NOVA1,DNHD1,IGSF11,CLDN11,GLIPR1L2,ETFRF1,PCDH8,ENPP2,GPR85,PFKFB3,XRN1,MTRF1L,PRIMPOL,PDZRN4,PMP22,TRHDE,LRP12,SCHIP1,LRRN3,CEP41,PRKCB,MAPK10,HYDIN,RELN,CNTLN,PTCH1,ANKHD1,BDNF-AS,PTN,TMEM260,ZSCAN32,PTPN13,PTPRB,PTPRD,PPP2R3C,KHDRBS2,MSANTD2,GTDC1,RFX3,SLC25A36,RIC8B,NUDT11,CCDC82,SETD5,ROBO2,RORB,ARMH4,LRRK2,ABCA11P,RTN1,CCDC112,TRAPPC13,ATXN7,SCP2,KIF16B,FBXO11,CNKSR2,NLGN1,WDR37,PPP4R3A,CCDC88A,SLC9A5,SLC12A2,ZNF334,CPEB4,SMARCA4,SMARCC2,MYH15,RCOR3,SNAP25,CMTR2,MYCBP2,SPP1,ZBTB43,LMO3,SAMSN1,THSD1,ZSCAN29,SEPT8,NUDT10,PLCB1,COBL,ANKRD28,ANKRD12,MTCL1,TBCEL,MGRN1,ATMIN,TCF4,SIN3B,DMXL2,CUX2,TRIM2,TCF12,SYNE1,PCDHB9,FRYL,CYB561A3,FAM200B,PMS2CL,C18orf54,ITGB3BP,TIAM1,TLR4,NR2E1,ERCC6L2,CSMD1,TP53BP2,CHST5,NR2C2,TRPS1,DCBLD1,TTTY15,HIRA,ZNF610,PLEKHH2,CCDC14,WRN,MKRN3,TCEAL7,ZNF138,CELF4,ZBTB38,ZNF177,FSTL5,ANKS1B,FTSJ1,INTS3,SLC38A1,LINC02210,FIP1L1,FAM47E,AMN1,FZD3,DOCK8,PHTF2,ACTR3B,ADAMTSL3" MicroRNA hsa-miR-96*:mirSVR_lowEffct hsa-miR-96*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-111 7.37E-108 4.67E-110 4.30E-109 298 1771 "RALGAPA1,KCNH8,CLK4,ABHD6,NCKAP5,FMNL2,ADD1,RNF150,HECW2,HACE1,ALCAM,SRPX,PCDH10,BBOX1,TRMT9B,ZFAT,PHF12,APC,ARNTL,MARCH3,PCDHGB4,NUMB,ZNF582,DPY19L3,MIR9-3HG,LDHD,FUBP1,MYRF,CACNA1A,CACNA1B,CACNB4,CABP7,CALM1,KALRN,RUNX1T1,USP6,SLC16A4,CD38,C1orf52,CDH2,DCLK1,SOCS6,SULT4A1,CNN3,IQCK,AKAP6,TOGARAM2,MYRIP,ZFP28,CRHBP,ANKRD44,TRIM69,SNCAIP,CSF1,CSF2RA,IPCEF1,SIPA1L1,VCAN,CNTNAP2,PLXNA4,GREB1,RUBCN,USP6NL,KIAA0408,TCAF1,HDAC4,MAML1,TMEM170A,DAPK1,AIF1L,ARMCX2,MYEF2,TMEM130,DDX46,SV2B,WDR20,DRP2,ECM2,KRBA2,GOLT1B,HIPK3,SEMA3D,FSD1L,PHF20L1,MBNL2,RASA4,KCTD3,EIF4G1,COPS4,RGS17,PCOLCE2,TMEM35A,PAN3,EPHB1,STX2,ERBB2,DENND4A,NRN1,F5,RPS6KC1,TAOK3,DLC1,CEP78,KAT8,SEC24B,FGF13,PRKAG2,SCARA3,RGPD5,ZMYND15,EVL,UFM1,AP4B1,MEGF10,DENND2A,B4GALNT1,ZNF234,ERAP1,TUBGCP4,PPARGC1A,SPIN1,STARD3,ZNF638,PRUNE2,PCLO,STMN2,GRIA2,ADAMTS13,RNF165,FAM107A,MUM1,TNFAIP8L3,HNMT,ZDHHC15,IRF8,KCND2,KLHL23,KPNA5,LIFR,SYTL4,HECTD2,GPR155,MAP4,MAP6,MAT2A,MBP,CHIC1,TM6SF1,MIA2,MYO5A,NEFM,NEK1,NF1,NRCAM,NTRK2,IGSF11,OXTR,GPR137C,GLIPR1L2,PCDHGC3,PDE4B,TMOD2,CYTL1,PFKFB3,PIK3R1,ZNF655,MAPKAP1,STRN3,LRP12,ING3,DRAM2,RANBP3L,VSTM2L,EPDR1,GDPD1,VPS13C,APTX,QRICH1,PTCH1,PTK2,ZSCAN32,ACSM5,TUG1,CEP97,USP47,ZCWPW1,KHDRBS2,GTDC1,RGS4,MRPS18A,KLHL11,RIC8B,RNASEL,ZNF532,ROBO2,MRAP2,ATP8B4,KCNIP1,RTN1,NCBP3,LRFN5,CASC3,FOXRED1,SH3GL3,CHD9,FHOD3,SYBU,SLA,PREX2,WDR47,CCDC88A,NAPB,BTBD7,CPEB4,SMARCA4,MYH15,ANKRD36,PDZRN3,MYO16,DOP1A,ZSWIM8,SP4,HECW1,TEX2,ZBTB43,SPART,ZC4H2,ERBIN,ZSCAN29,KANK1,KLHL7,NECAB1,JMJD6,ADAMTS17,SYP,TACC1,MTCL1,PJA1,MCF2L,IQCE,KLHL4,TCF4,DMXL2,ZFP90,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,PCDHB6,USP32P1,DICER1,ZFPM2,ITGB3BP,AP4E1,ZNF106,SLC44A1,C9orf85,DOK6,NR2C2,SYNPO2,TRIO,RPL7L1,UBE2H,UGT8,PLEKHH2,TBC1D15,WIPF1,WRN,PCDH20,ZBTB14,ZNF24,KCNT2,TRIM9,ZBTB38,SLC30A4,SLC38A1,EVI5,STOX2,RNF103,FAM13C,FZD3,SMIM8,ADAMTSL3,RNF170,SOCS4,ST8SIA2,GAN,FAM198A" MicroRNA hsa-miR-150:mirSVR_lowEffct hsa-miR-150:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-111 8.02E-108 5.04E-110 4.64E-109 313 1952 "ASIC1,CLK4,XKR4,NDRG3,KLHL32,ADCY6,RNF157,ADD1,ADORA2A,PTCHD1,MTA3,HACE1,CC2D2A,ALCAM,ARHGAP20,ZFAT,MYH7B,APBA2,KCNAB2,LGR5,ARRB2,SLC4A4,SLC2A11,N4BP2L1,TTLL9,ADAM15,BACH1,ADGRB3,LINC00847,BMPR1B,ARHGEF7,GPC2,CACNB4,CAMK2G,VXN,PRC1,METTL6,P2RX6,CD86,CDH2,MAGI1,CRLF1,MS4A7,C7orf61,MYL6B,HECTD1,MAP4K4,CNGA3,SUMF2,SLC4A8,AHCTF1,SNCAIP,RGS6,CSF2RA,OSBPL3,GREB1,DOCK4,MYADM,GAPVD1,ARHGAP24,LONRF1,PABPC5,ELMSAN1,C2CD2L,KIAA0319,POM121,RHOBTB1,SACS,ZNF582-AS1,DLX1,RPS6KL1,NR1D2,SLC25A18,RCAN1,ARRDC4,MAMLD1,DNAJB6,E2F5,EDNRB,KLHL5,YAF2,MRO,TMEM132E,AASS,C8orf37,SRRM1,NCALD,PIPOX,ANKMY1,NSRP1,SCML2,RACK1,STRADA,ZNF589,FGF14,FGFR1,AMOTL2,PRKAG2,POLK,UBE2E3,IP6K2,VTI1B,AGAP2,ATP13A4,NOP56,DCTN2,C2orf88,TMEM107,ERGIC3,MSANTD4,SARAF,ZMAT1,GABRA3,ERAP1,MTHFD2,C15orf41,CPLX2,MSTN,MMADHC,GGT7,RAB30,ZNF638,KDM2B,LUZP2,RAB40B,LILRB4,GRIA2,PLPP7,SPACA9,GSN,FAM19A2,GUCY1B1,ZDHHC15,MSL1,DISP2,ZNF678,INPP5B,ITGAM,SLC35G1,KCNN3,LINC00634,KTN1,LSS,MAN2A2,MAP4,MBNL1,AFF1,ZNF680,PTOV1,MXI1,MYO5A,RTL5,NCAM2,NEFM,NELL2,NF1,SLC11A2,SMIM11A,NTRK2,NUCB2,FAM225B,P2RX7,GPR137C,GPR85,PFKFB3,DUSP26,NLGN3,NALCN,SEMA5B,PIK3R1,XRN1,SMOX,MAPKAP1,LRP12,POU6F1,PPM1B,PPP2R2B,MAPK9,APTX,GDPD2,PIGG,PTCH1,PTK2,STK32A,PTPRB,PTPRN2,RIPOR1,CCDC40,FAM66C,C1orf54,ZNF493,DPF2,PRRT2,RGS3,KIF7,KLHL11,PBRM1,SETD5,EXD2,ARMC5,CARF,ROBO1,PGBD4,FBXW7,ZNF671,ADAL,FAM161B,MEG3,HSD11B1L,ST6GALNAC6,CLIP1,FAM192A,SCN2B,SCN8A,GALNT10,FOXRED1,SCAF8,PPM1E,ASAP3,FBXO11,FNDC3A,ANKRD6,PPP4R3A,KANSL3,ZNF430,ARHGEF40,SLC14A1,TET1,CPEB4,ZNF667,SMARCC2,MBD5,SNRPN,TMCC1,BDP1,ZSWIM8,GLT8D1,TEX2,DDN,NFASC,SSTR2,ZC4H2,ZSCAN29,DIP2A,PHLDB1,NSFL1C,PRRC2C,DNAJC9,TMEM150C,SYN2,TACR1,EXOC7,FBXW11,TRIM2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,DICER1,SIRT1,AP4E1,GPR161,TIAM1,TMEM9,TK2,FAM124A,R3HDM1,KAT6B,ZNF346,STXBP4,DCBLD1,TTTY15,PRR18,CLHC1,RPRM,EIF4ENIF1,USP1,VLDLR,TBC1D15,WIPF1,RICTOR,ZBTB14,ZNF28,KCNT2,ZNF45,ZNF74,CELF4,ZSCAN26,ZNF189,ZNF213,DHX33,SLC30A4,MAP3K12,DNALI1,LINC02210,ADAMTS9,KCNAB1,PARP11,PDSS2,FAM13C,KAT6A,SMIM8,HNRNPA3,RNF170,FRMD6,NETO2,AP3B2,LAS1L" MicroRNA hsa-miR-138-1*:mirSVR_lowEffct hsa-miR-138-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-111 8.53E-108 5.33E-110 4.91E-109 286 1632 "AS3MT,CCDC85A,TMCC3,RNF150,PTCHD1,INTS2,HECW2,KCTD16,HACE1,CC2D2A,HFM1,TAOK1,ALK,AMPH,OGT,CCDC146,PHF12,APBB2,UPRT,CPNE5,CASK,TMEFF1,ZBTB10,NCOA1,NUMB,ATP6V1G2,DOCK11,CFLAR,SYNJ1,ARHGEF7,FUBP1,NAE1,BTK,CA8,CACNB4,CALB2,SCARB1,CD38,C1orf52,CDO1,CCPG1,NOG,CHGB,CNOT8,QKI,CNN3,CNR1,AKAP7,ARMC8,SLC4A8,RCHY1,CNRIP1,AKAP12,GDA,CSNK1E,SIPA1L1,FAM169A,ERC2,GREB1,PUM1,DCAF4,CYBB,HDAC9,ZFYVE16,DGKB,TMEM170A,IP6K1,PABPC5,DBI,ARMCX4,MYEF2,KIAA0319,ALKBH8,RHOBTB1,SACS,SV2B,CDON,DMTF1,PDCD6IP,MAMLD1,FARSB,E2F6,MBNL2,EGR3,COPS4,RGS17,STARD3NL,C8orf37,RCAN2,ERBB4,ERCC2,DENND4A,RRAGB,ADGRV1,EYA1,MRVI1,SCML2,CEP78,UBE2E3,MEX3B,TMEM107,ATP6V1H,ATP2C1,ZNF605,ERGIC3,CELF1,FYB1,GABRG2,GAD1,GALC,ZNF234,DISC1,KIAA1841,IGSF5,PCDH17,LYVE1,TTBK1,CRCP,TCERG1,DBF4,RAB30,FERMT2,TDRKH,GPR12,STON1,GPR34,GPR37,BTN2A1,GUCY1A1,GUCY1B1,IRAK3,HAS2,UBE2QL1,TOX2,ARHGAP36,HMGCL,HNMT,HSF2,ZIC5,RBPJ,LRRCC1,IL6ST,ZNF678,ITPKB,JAK2,KCND1,KCNN3,L1CAM,LAMP2,STMN1,PAXBP1,PIK3AP1,MARK3,ADAM11,MEIS1,KCTD6,AFF1,COL28A1,SAMD5,NRBP2,N6AMT1,MYO6,MYO9A,MYT1,NELL2,NF1,CNOT4,NPTX2,NTRK2,NUCB2,CHAMP1,PCDH9,PFKFB2,PIK3C2A,PIK3R1,PLCL1,KANSL1,RASGEF1B,MAPK9,DCHS2,SAMD9,WBP1L,CNTLN,PTCH1,ELOVL2,PTPN13,PTPRG,TUG1,ZNF793,NWD1,RAP1GDS1,ZCWPW1,OXR1,RBBP6,RET,GTDC1,FIGN,RGS4,RGS12,CARF,ROBO1,CCDC25,ELP2,CCDC102B,NEK11,MCMBP,GLDN,LRRK2,ABCA11P,ZNF568,SEMA6D,ATXN2,SCN7A,TNFRSF19,ZFP2,TRA2B,PPM1E,ARX,FNDC3A,SEC31A,WDR37,BTBD3,SLC9A5,SLC12A2,SMARCC2,OGDHL,CDK5RAP2,ANKRD36,FAIM2,LMBRD1,BDP1,NMNAT2,UNC5B,CDK19,MCF2L2,ITPRID2,SAMSN1,NXT2,ELOVL4,DIP2A,ARHGEF9,SYP,SYPL1,C12orf76,TACC1,EXOC7,DNMBP,TAL1,ADGRL3,ZEB1,TRIM2,PCDHGA11,PCDHB9,TEK,ZFPM2,AP4E1,MTMR14,PIK3R5,TPM2,STXBP4,TRPS1,TSN,EIF4ENIF1,GORASP1,FLRT2,LAT2,GUSBP1,XPO1,XRCC4,ZIC1,ZNF23,ZNF540,ZBTB38,ZSCAN26,ANKS1B,CADM2,RNF103,WNK3,PARP11,RGS7BP,DNAH10,FAM219B,ADAMTSL3,ZDHHC20,SOCS4,FAM198A" MicroRNA hsa-miR-508-5p:mirSVR_lowEffct hsa-miR-508-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-111 1.23E-107 7.65E-110 7.04E-109 306 1870 "SYN3,ACADM,ADCY6,TMCC3,ADD2,ADORA1,BEND6,INTS2,HECW2,TBC1D14,AMPD2,AMT,OGT,EP400,PI16,CCDC146,NT5C3B,BCAS1,CDC14B,SFMBT2,IGDCC4,ZFYVE28,DPY19L3,ATP6V0A1,DOCK11,ADAM15,BACH1,LINC00847,BCL7A,KSR1,DST,CASTOR3,CACNA1G,DDR1,LURAP1,KALRN,PTBP2,CAMK2G,HIP1R,NFS1,ZNF501,KRIT1,USP2,P2RX6,ARHGEF2,ZMYM4,CDO1,RCBTB2,FOXN3,MAP4K4,COL9A1,SLC4A8,ABI3BP,SMARCAL1,MYRIP,C2CD2,HAPLN1,RNF14,GALNT9,VAC14-AS1,FAM169A,DCAF4,BOC,ARHGAP32,MAML1,DAPK1,YTHDC1,DGCR5,MYEF2,KIAA0319,SNAP91,SACS,SPOCK3,ZNF582-AS1,CHRDL1,CDON,DMTF1,DPH1,DRP2,DTNA,DNM1L,EDN3,PHC2,CNNM1,HEYL,PHF20L1,MRO,RASA4,GOLGA7,DCTN4,RCAN2,EPHB1,STX2,RRAGB,ADGRV1,FAM198B,TUBB3,SCML2,DLC1,ZNF589,PCYOX1,SEMA4D,FLT1,SLC37A3,NELFCD,NBEA,SMC2,UFM1,CAMKK2,ZNF605,PRELID3A,KHDRBS3,DLL3,SARAF,TVP23A,SDCBP2,RAPGEF6,IP6K3,C15orf41,NEU3,TUBGCP4,CSDC2,PPARGC1A,DHRS4,GLUL,KDM2B,LUZP2,KCNMB4,GPD2,GRB10,DIDO1,SERP2,PRDM5,RNF165,BVES,AP4S1,SOX21,LINGO1,SLC2A6,MAN1B1,HMGCL,HNMT,CELF5,FAM95B1,IL6ST,SLC35G1,KCND1,KCND2,KLHL23,CREG2,KIT,KPNA5,IPO5,TTYH2,LIFR,SYTL4,NCOA7,MATN3,MEIS2,KITLG,GIT1,MSI1,NRBP2,MYO6,NFE2L2,NME4,NOVA2,SLC11A2,NTRK2,NUCB2,IGSF11,ZNF713,ETFRF1,PDCD2,CYTL1,PFKFB4,ZNF655,CCSER2,GPSM2,JAKMIP1,SLC25A23,STRN3,EPB41L4B,FSD1,POU6F1,MINDY2,MAPK3,HYDIN,SAMD9,WBP1L,PTPN13,PTPRB,PTPRH,C1orf109,FAM66C,NWD1,OXR1,RASGRF2,DPF2,FIGN,RGS3,RGS4,PBRM1,RNASEL,PCMTD2,SPIN3,MEG3,ABCA11P,ST6GALNAC6,KCNIP3,RTN1,ZNF568,RYR3,ATXN2,HES6,ZFP2,FOXRED1,RASA3,HSPA4L,KIF21A,CPEB3,AMBRA1,NLGN1,DZIP1,WDR37,BTBD3,WDR47,ARHGEF40,SLC9A5,SLC12A2,SLC12A4,ARFGAP1,ZKSCAN3,SMARCA4,RCOR3,MAPKBP1,MBD5,LMBRD1,FAM126B,PDZD2,GLT8D1,ZNF423,ITPRID2,ZNF302,SAMSN1,ZC4H2,SSPO,SEPT8,TTBK2,RGL1,ADHFE1,STX1A,KANK1,SULF2,ARHGEF9,VPS13A,SYP,CAMTA1,MLST8,ADGRL3,FBXW11,TPCN2,TCF12,USP22,SYNE1,SLC19A3,NSD1,PCDHA5,DICER1-AS1,ZNF106,TIAM1,RELL2,KAT6B,PIK3R5,DOK6,SMUG1,NEIL2,USP1,VLDLR,CLDND1,RICTOR,LGI4,SLC47A2,ZNF24,ATP6V0E2,ZNF138,ZNF184,ZNF189,ANKS1B,ZXDA,CADM2,LINC02210,PRDM8,NAV3,URM1,PPP1R3F,KCNAB1,PLSCR4,EPM2A,DOCK8,PHTF2,ACTR3B,JMJD1C,TRAM2-AS1,FRMD6,SPATA13" MicroRNA hsa-miR-26b:mirSVR_lowEffct hsa-miR-26b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.39E-111 1.34E-107 8.24E-110 7.59E-109 310 1919 "KCNH8,KLHL32,AXIN2,RNF150,ADRB2,DPY19L2P4,MTUS1,KCTD16,WDR35,SPARCL1,ABCD2,ARHGAP20,PCDH10,FAM135A,SYT13,AMPH,AMT,OGT,ANK2,PPFIA4,PKP4,EPB41L5,USP37,LGR5,PPP4R4,CASK,MYOM1,DOCK11,SEC11C,NRP2,MTMR2,CACNA1G,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,SLIT2,RAB28,PPT2,C4orf33,CNTFR,AKAP6,COL9A1,AKAP5,SLC4A8,ZFP28,CPS1,FAM171B,PREPL,CREM,ANKRD44,SUSD5,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,RIMS2,GPSM1,CCDC144A,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,LIN54,MATR3,DGKB,PABPC5,DNAL1,ARMCX4,ARMCX2,YTHDC1,ZBTB24,ELMO1,KIAA0753,KLHL3,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RAB39B,DYNC1I1,CPEB2,DOCK2,DRP2,ECM2,MAMLD1,GOLT1B,AASDH,EDIL3,EDNRB,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,C8orf37,DCTN4,USPL1,ENPP6,GPHN,CDKL3,EYA1,MRVI1,F5,F8,ACSL4,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,PRKAG2,POLK,UBE2E3,IP6K2,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,ZMAT1,GABRB3,GABRG1,FAM120B,GATM,IGSF5,MSTN,NFU1,PCDH17,MALT1,TCERG1,SPIN1,GLI2,FERMT2,GPR12,GPR37,TMEM121B,PCLO,GRIA2,PLCD4,ATE1,ZBTB45,GUCY1A1,RASSF8,DDX19B,ARHGAP36,ELOVL5,HNMT,AGFG1,HSPA1L,SMAP1,IGF1,SCIN,IL12A,ZNF678,INPP5B,JAK2,SLC35G1,METTL21A,KCNB1,IPO5,STXBP5,KTN1,STMN1,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,SAMD5,MSI1,MT1M,LAYN,MYO5A,NEFH,NOVA1,SMIM11A,PCDHGC3,PCSK5,PDE4B,PFKFB2,SCHIP1,SH3KBP1,CCDC144B,LRRN3,PPP2R5E,PRKAB2,RASGEF1B,PRKACB,RELN,SNRK,CNTLN,PTCH1,ANKHD1,BDNF-AS,TMEM260,PTPRB,EML5,PTPRE,PTPRH,PEX2,ZSCAN2,TUG1,PID1,ACSS3,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,RET,REV3L,ERI2,GTDC1,RNASEL,LGI2,CCDC82,EXD2,C12orf49,ALG9,SNX22,RPS6KA2,KCNIP3,RYR3,ATXN2,TNFRSF19,SUPT20H,FERMT1,FNDC3A,CNKSR2,NUBPL,WDR37,PPP4R3A,SLC6A8,SLC12A2,SNRPN,FAM126B,TRERF1,BDP1,KDM4C,ERC1,PEG10,RBM26,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,SYN1,COBL,CAMTA1,ALG1,DMXL2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,FAM200B,SIRT1,ZFPM2,ITGB3BP,ZNF106,AKTIP,SLC44A1,TLR4,NPL,RGMB,SYNPO2,TRIO,GORASP1,FLRT2,WIPF1,XPO1,ZBTB14,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,URM1,KCNAB1,DOCK8,PHTF2,FBXO36,ACTR3B,NETO1,CPNE4" MicroRNA hsa-miR-130b:mirSVR_highEffct hsa-miR-130b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.07E-111 1.72E-107 1.06E-109 9.72E-109 265 1401 "CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,SPARCL1,SPOP,SRPX,FAM135A,LRCH2,LCORL,PHF12,APAF1,LINC00173,STK33,NCOA1,STX16,ZNF583,DPY19L3,ADAM23,TTLL9,BACH1,ADGRB3,NRP2,DST,SYNJ2,C5,CACNA1B,THSD7A,KALRN,CAST,CERS5,USP6,SEPT7,TIGD7,CFL2,PLAA,CLTC,FHL5,CNR1,AKAP7,FAM149A,AKAP6,TBPL1,MYRIP,CLOCK,CREM,GDA,CSF1,LRIG1,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,LONRF1,SPATA2,YTHDC1,FBXL5,KIAA0319,DDX46,RHOBTB1,WDR20,CPEB2,DPYSL2,ABCC5,GOLT1B,AASDH,SNX29,WDPCP,EDN1,EDNRB,KMT5B,EGR3,ASB3,PLEKHA1,CERCAM,PAN3,ENPP6,RABEPK,DENND4A,CEP85L,RASL12,ACSL4,GORAB,MED12L,FGF11,FGF12,FGF14,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,FLT1,NBEA,MEGF10,B4GALNT1,ZNF274,ERAP1,GCNT2,ARFIP1,ADAM28,RAB30,TNRC6A,KDM2B,MAP7D2,LUZP2,RAB40B,FERMT2,PRUNE2,GPR34,GRB10,CIT,RNF165,TOX2,HNF4G,NEGR1,IRF8,MSL1,ZIC5,LRRCC1,ZNF678,CREG2,IPO5,LIG4,SMAD1,SMAD9,MAP4,MARK1,MATN3,MBNL1,LYRM9,MYO9A,ZNF862,MYT1,NEK1,NFE2L2,CNOT4,OCRL,OPA1,GPR137C,PCSK5,PDE1C,CCSER2,JAKMIP1,PLIN1,PURG,LRP12,PPP2R5E,KANSL1,PSD,MTMR10,PTPRG,PID1,CEP97,RAD17,RBBP8,ZDHHC14,RDX,RET,SLC25A36,KLHDC8A,CARF,ROBO2,EPHA10,LRRK2,CLIP1,RTN1,SEMA6D,TNFRSF19,PEAR1,SEC14L1,ARX,KIF16B,CHD9,SYBU,ABLIM3,BTBD3,WDR47,SEPHS1,SLC8A1,CCDC88A,BTBD7,SNAP25,KIF13A,USP33,TRERF1,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,FBXW11,CUX2,PCDHB4,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,SLC44A1,BHLHB9,ERCC6L2,R3HDM1,CSMD1,TNS1,NPL,SMUG1,TSC1,UBC,FAM155A,WRN,CFAP298,ZIC1,ZNF711,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,UPF3A,MAP3K12,MFF,STOX2,KCNAB1,PLSCR4,RGS7BP,UBE3B,PHTF2,NHSL1,FXR1,FRMD6" MicroRNA hsa-miR-376b:mirSVR_lowEffct hsa-miR-376b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.95E-111 2.21E-107 1.35E-109 1.24E-108 286 1638 "XKR4,GALNT13,RNF150,ZNF608,AGT,RTL9,KIAA1324,CC2D2A,C1QTNF1,ALCAM,FAM135A,GPRASP2,TRMT9B,PITPNM2,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,MAGEE2,USP37,ZBTB10,NUMB,TMEM108,SLC4A4,DPY19L3,CFLAR,BMPR1B,DST,SYNJ1,MTMR2,KALRN,PTBP2,SPAG9,NFS1,ENTPD6,CDH2,DCLK1,ZMYM4,LRRFIP1,LOC730101,CHN2,CHRNA4,B4GALT6,RAB33A,CLCN3,SRP14-AS1,HECTD1,FHL5,CNN3,ARMC8,SUMF2,RTTN,ZNF521,NRG2,PREPL,CREM,NCOR1,CLIP3,CSF2RA,ARHGEF10,CNTNAP2,DZIP3,PHF14,PNPLA8,CTH,PUM1,FAM131B,DCAF8,ZNF337,PABPC5,DNAL1,JAKMIP2,LYPD1,DDX46,SPOCK3,DLX1,GRIN3A,DMD,NR1D2,DOCK2,ACOT8,GOLT1B,CNNM1,SEMA3D,FRY,YAF2,FAM13A,KMT5B,AASS,EIF4G2,EIF5,PLEKHA1,RGS17,CALCRL,VPS13B,LRRC17,DENND4A,EXTL2,F5,SCML2,ST3GAL6,ZSCAN30,SEC24B,FER,FGF1,FGF14,FGFR1,SUCO,UBE2E3,PCYOX1,FLT1,NOP56,PDLIM5,MSANTD4,MEGF10,CHL1,GABRG1,GABRG2,IQGAP2,DISC1,KIAA1841,MSTN,PCDH17,PPARGC1A,GLI2,MSL3,LUZP2,GPD2,LILRA2,GPR12,GRIA2,SERP2,ATE1,AP4S1,LINGO1,MAP4K5,NEGR1,NKD1,RBPJ,LRRCC1,IL6ST,INPP5B,JAK2,SLC35G1,LIMS1,MATN2,MBP,CHIC1,MEIS2,MEST,KCTD6,AFDN,ZNF680,SAMD5,BLOC1S2,MSR1,ZNF92,NEXMIF,ZC3H12B,NFE2L2,NPTX1,NTRK2,GPR137C,PAX6,PCDH8,PCSK5,ENPP2,PFKFB3,NALCN,PIK3C2A,PIK3R1,ZFYVE21,XRN1,PLCL1,PLIN1,PURG,PDZRN4,STRN3,RETREG2,PPARA,RASGEF1B,PRKCB,DIRAS2,BCAS3,ANKHD1,PTN,TUG1,TMEM255A,SH3TC2,RAP1GDS1,ENOX1,OXR1,MSANTD2,REV3L,RFX3,RGS12,RIC8B,RNASEL,LGI2,ARMC5,CCDC102B,FBXW7,ZC3H14,ADAL,MEG3,HUNK,ATAT1,ZNF354C,CCDC112,DGLUCY,SATB1,LRFN5,SCP2,FNIP1,KIF21A,SH3GL3,PPM1E,FNDC3A,R3HDM2,NLGN1,DZIP1,BTBD3,ZNF334,CPEB4,ZFP1,SMARCC2,ANKRD36,SNRPN,FAM126B,TRERF1,UHRF1BP1L,CLASP2,TROVE2,CEP68,TTBK2,ADHFE1,KANK1,SEPT3,KLHL7,PLCB1,SYN2,SYPL1,PDLIM2,MGRN1,SATB2,TPCN2,RPGRIP1L,PCDHB7,PUM2,USP32P1,ARHGAP9,SLC35G2,DICER1-AS1,ITGB3BP,TP53BP1,NPL,C9orf85,STXBP4,TSN,ZKSCAN5,SGK3,FAM155A,UBE2H,PLEKHH2,XPO1,XRCC4,MICU3,ZNF28,ZNF32,AGMO,TMEM237,ZNF177,EML6,ZSCAN26,INTS3,EMSY,CADM2,STOX2,FAM47E,FAM13C,AMN1,DOCK8,RSPRY1,RNF170,KLHDC1,NETO1,SOCS4" MicroRNA hsa-miR-1197:mirSVR_lowEffct hsa-miR-1197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.99E-111 2.23E-107 1.35E-109 1.25E-108 303 1838 "KCNH8,CLK4,NCKAP5,SYS1,XKR4,NDRG2,ADD1,USP31,UNC5A,KLHL13,HACE1,TAOK1,USP35,ALCAM,ARHGAP20,MARCH4,LCORL,SEMA4G,IGDCC4,TMEFF1,NUMB,SLC4A4,N4BP2L1,ATP6V0A1,ADAM15,LINC00847,BCHE,KSR1,CA12,CACNA1A,CACNA1B,PTBP2,CAMK2G,CAST,ISPD,SYNGR3,ENTPD6,MAGI1,CACNA2D2,CFL2,FOXN3,CHN2,CPNE6,NRXN3,DGCR9,SRP14-AS1,CNTN1,IQCK,AKAP6,AKAP5,SLC35F1,PREPL,HAPLN1,NCOR1,ABCG1,CS,CSF2RA,OSBPL3,VAC14-AS1,PDE4DIP,PLXNA4,ZSCAN23,MYADM,EARS2,LONRF1,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,ZBTB24,MFAP3L,KLHL3,LYPD1,SGSM2,TMCC2,SLC29A4,DYNC1I1,DPP6,PDCD6IP,DTNA,ECM2,WDPCP,APH1A,MBNL2,KMT5B,PCOLCE2,ELN,ENO2,RCAN2,LRRC17,EPHB1,ERBB2,ZNF549,SPEG,EZH1,SCML2,RACK1,CEP78,FCGR3A,FCGRT,FGF11,SPSB4,FGF13,FGFR1,SEC23B,ANKFY1,WDR83,PDLIM5,CAMKK2,ZNF605,KHDRBS3,FYB1,ZMAT1,GHDC,DISC1,SEPT9,INPP5K,CPLX1,GFER,PCDH17,BRD8,ZNF276,RNPS1,RAB30,MSL3,DCLK2,GPD1,TDRKH,GRIA2,DIDO1,BTN2A1,GSTT2,IRAK3,RASSF8,FRMD5,GABARAPL2,HMGCL,NEGR1,LRRC75A,SHISA6,ICA1,EID2B,LRRCC1,IL6ST,IBA57,LRRTM1,SLC35G1,KHK,KIF5A,STMN1,HECTD2,ZFYVE27,MAP6,MARK1,MBD1,MBP,TM6SF1,KITLG,PPM1L,POC1B,AFF1,MPP2,PTOV1,LYRM9,MYO7A,NCAM2,ZC3H12B,NFIX,NNAT,NOVA1,DNHD1,SMIM11A,NUCB2,OCRL,PAX6,PCDH9,GPR85,PFKFB3,NLGN3,PIK3C2A,SNX10,KCTD15,PLIN1,SMOX,MTRF1L,TRHDE,LRP12,RETREG2,PPP2R5E,MAPK9,MAPK10,MASP1,RELN,CNTLN,PTK2,PTPRB,ZSCAN2,RAD51D,ZNF793,IQSEC3,RASGRF1,RASGRF2,CRTAC1,DPF2,RGS12,RIC8B,C12orf49,RORB,BAALC,GLDN,SGSM1,STK32B,ABCA11P,NCBP3,SATB1,CSRNP3,SCN2B,SCN7A,PRCD,GALNT10,COPZ1,SH3GL3,FERMT1,ASAP3,MYO18A,SEC31A,PPP4R3A,LIMS2,KANSL3,SLC11A1,SLC12A2,TET1,CPEB4,SMARCA4,INTS9,INAVA,LIMCH1,SNRPN,DOP1A,NMNAT2,MYCBP2,TEX2,ZNF423,NFASC,ATP10B,CLASP2,ITPRID2,LARP4,ZSCAN29,TTBK2,STAC2,ARHGEF9,DNAJC9,SYN1,COBL,MTCL1,ATMIN,TCF4,TCF12,SYNE1,CYB561A3,TEK,FAM200B,AP4E1,CDH22,TK2,ACTR6,ANKRD24,PIK3R5,RASD2,TPM1,WBP2,TRO,TTTY15,CLHC1,TUBB1,EIF4ENIF1,UCHL1,GORASP1,OSBP2,CCDC14,VLDLR,TBC1D15,WRN,RICTOR,ZNF19,ZFP41,ATP6V0E2,CRB2,LYPD6,POLR3H,EMSY,RNF103,FAM13C,MARCH8,CASC15,ACTR3B,FAM219B,NHSL1,ZDHHC20,IFT88,FAM198A" MicroRNA hsa-miR-4267:mirSVR_lowEffct hsa-miR-4267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.14E-111 3.44E-107 2.07E-109 1.91E-108 305 1865 "DGCR6,ABR,ASPHD1,ASIC1,NCKAP5,ADCY6,GALNT13,ADORA2A,PWWP2A,KIAA1211,KCTD16,TBC1D14,C1QTNF1,ABCD2,CARNS1,AMPD2,DPP10,SEMA7A,CCDC146,FAM131A,PPFIA3,USP37,CDK10,PLA2G4C,LINC00173,PDE8B,MARK4,CHRD,ATP1B3,ALDH7A1,DOCK11,ADAM23,CARMIL3,RGS9,KSR1,ARHGEF7,NAE1,C5,LDLRAD4,CAMK2G,RUNX1T1,CBR1,CERS5,CD86,CD38,DGKI,CDH2,LRRFIP1,DLGAP1,CDR1,CHN2,CNOT8,TAOK2,NDST3,CLCN3,ABCG2,MYRIP,ZNF521,ZFP28,CREM,SH2B1,TRIM69,MROH8,LRIG1,GALNT9,VAC14-AS1,PDE4DIP,RASGEF1C,DZIP3,PPP6R2,DCAF4,RUBCN,CYBB,HDAC9,GPRASP1,INTS1,DGKB,DAPK3,SPATA2,DGCR5,FBXL5,RUSC2,KLHL3,GSDME,POM121,GRIN3A,RAB39B,HS3ST2,CD99L2,DYNC1I1,CPEB2,SLC25A18,ACOT8,DNAJB6,SEZ6L2,SEMA3D,PHF20L1,APH1A,MRO,GOLGA7,TENM1,CALCRL,HSD17B14,EPB41,NCALD,DNAJC27,RASL12,PTK2B,TUBB3,FCGR1A,FCGRT,FDFT1,FER,FGF1,SUCO,MEX3B,PCYOX1,SYNCRIP,RGPD5,SEMA4D,ATP13A4,NOP56,FLYWCH1,SPECC1,ATP2C1,CELF1,NSG1,BRSK1,FYB1,ZNF274,ERAP1,TMEM8B,DISC1,TUBA8,ARFIP1,SESN1,MALT1,GLI2,GLYR1,RAB30,POLL,DCLK2,GPD1,CCDC184,LPAR4,GPER1,GRIN2C,ZNF496,BTN2A1,FAM19A2,RNF165,GSTM5,ZBTB49,PACSIN2,MAN1B1,ATXN2L,MIER3,ZDHHC15,LRRC75A,SHISA6,CELF5,C2orf72,LRRCC1,TJAP1,SLC6A17,ITGAM,SLC35G1,KCND1,HECTD2,MAN2A2,ZFYVE27,MAT2A,AQP11,MBD1,CHIC1,MEIS1,PPM1L,AFF1,PTOV1,MX1,MYO7A,RTL5,ZNF862,ZC3H12B,NME4,CNOT4,DNHD1,NUCB2,OGG1,LOC100128398,ZNF827,PFKFB2,NLGN3,TMIE,JAKMIP1,ING3,FA2H,POLR2F,PPP2R5E,PSD,PIGG,BDNF-AS,ZSCAN32,PTPRB,PPP2R3C,SLC25A48,ZCWPW1,TRIM68,RGS3,RGS4,RGS12,RIC8B,ARMC5,KIRREL1,ROBO2,NEK11,TCP11L1,STK32B,ZNF331,SATB1,PRCD,TNFRSF19,CASC3,SH3BP2,KIF16B,ASAP3,ANKRD6,PKNOX2,NAPB,SMARCC2,CDK5RAP2,INTS9,IFT122,INAVA,LIMCH1,MBD5,SNRPN,FAM219A,DOP1A,DOK5,SP4,NMNAT2,TEX2,ERC1,SPTAN1,IQSEC2,RBM26,NFASC,CLSTN2,POGZ,ZC4H2,RGL1,DIP2A,STAC2,KLHL7,NECAB1,JMJD6,SUPT5H,SYNE2,SYT1,ANKRD28,EXOC7,AGTPBP1,MGRN1,NAT16,USP32P1,FRYL,CYB561A3,ZNF106,ARL10,THRA,ENHO,TNS1,SMUG1,TTTY15,LINC00689,UGT8,BCL2L13,VLDLR,WIPF1,LAT2,CLDND1,ZIC2,ZNF711,ATP6V0E2,MKRN3,TMEM237,ZNF189,SPIRE1,MFF,GDPD5,LINC02210,STOX2,PRDM10,MDH1B,GJC2,ACTR3B,FAM219B,JMJD1C,MSRB3,TTC7A,ZDHHC20,FRMD6,RNF146,SPATA13" MicroRNA hsa-miR-362-3p:mirSVR_lowEffct hsa-miR-362-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.11E-111 4.54E-107 2.72E-109 2.50E-108 299 1795 "VWA5B2,RALGAPA1,ABCF1,KCNH8,CLK4,CCDC85A,ADD1,CC2D2A,TAOK1,SMIM17,SEMA6A,ALCAM,ABCD2,AMPD2,DPP10,FGD2,PPFIA4,PKP4,APBA2,FAM131A,PHYHD1,SHROOM2,NCOA1,NUMB,INSYN2B,SLC2A11,RNF182,ADAM15,ADGRB2,NRP2,BMP7,FUBP1,NAE1,BTK,GYG2,BAIAP3,LDLRAD4,CFAP410,CACNA2D1,CALM1,KALRN,CAMK2B,VXN,CLDN10,LDB2,METTL6,USP6,DCLK1,L3MBTL4,CCPG1,NOG,NUMBL,CACNA2D2,B4GALT6,CPNE6,HECTD1,CNR1,AKAP7,AHCTF1,RTTN,CREM,CRY2,HINFP,ANKRD44,GDA,CSNK1E,SUSD5,PLXNA4,SLITRK5,DZIP3,ERC2,APPL1,HDAC4,RASSF2,MATR3,SPOCK2,DNAL1,ZBTB24,GSDME,PLPPR4,SNAP91,SACS,SV2B,WDR20,CHRDL1,EXOG,GRIN3A,DMD,DMPK,CASP8AP2,PDCD6IP,DTNA,MAMLD1,ABCC5,CNNM1,SEMA3D,APH1A,KMT5B,EGR3,TENM1,EPB41L2,ENPP6,GPHN,ERBB2,DENND4A,DLC1,PRKAG2,PCYOX1,SYNCRIP,RGPD5,FOXO3,COQ5,SMC2,FAM49B,ZNF605,ERGIC3,CELF1,CGREF1,NSG1,STAU2,ABLIM2,CHL1,GABRG2,GALC,TMEM8B,CPLX2,SESN1,BRD8,TXNL4A,TCERG1,CBX1,GNAO1,ZNF782,GPT2,ADGRA3,PRRC2B,LILRB4,PRUNE2,CCDC184,MCHR1,GPR34,PCLO,GRIA2,DIDO1,ADAMTS13,RNF165,GSTM5,AP4S1,PSIP1,IGFBPL1,IRF8,MSL1,RBPJ,TMEM240,ZNF678,ITGA7,KCNH2,KIF2A,STXBP5,LAMP2,LMO2,SYTL4,HECTD2,NCOA7,MAP2,MARK3,MAT2A,CHIC1,MEIS1,MGAT3,LYRM9,MYO7A,MYT1,P2RY13,NEK1,NOVA2,NUCB2,GPR137C,PALM,CNTN3,PDCD2,NALCN,GPSM2,PRIMPOL,MAPKAP1,LRP12,EPB41L4B,PPM1B,RASGEF1B,MAPK4,PRPSAP2,VPS13C,PTCH1,PTPRD,RAD17,FAM66C,SH3TC2,RADX,KHDRBS2,ZDHHC14,RDX,REV3L,RIC8B,RNH1,KLHDC8A,EPHA10,BAALC,ZNF671,SGSM1,MEG3,ST6GALNAC6,ZNF331,DGLUCY,SATB1,FNIP1,CASC3,MRAS,FAM102A,FERMT1,SEC31A,DZIP1,ANKRD6,KANSL3,SLC6A11,SLC12A4,NAPB,ELMO2,SLC22A4,CPEB4,CDK5RAP2,MYH15,IFT122,SNRPN,MYO16,FAM219A,TRERF1,BDP1,ZSWIM8,SP4,SPP1,KDM4C,ZC3H13,NFASC,POGZ,ITPRID2,ZC4H2,MPRIP,SEPT8,TTBK2,SULF2,ZC3H4,ADAMTS17,SYPL1,SYT1,COBL,CAMTA1,MLST8,TAL1,ADGRL3,AGTPBP1,TBL1X,SIN3B,DMXL2,ZFP90,TPCN2,USP22,SYNE1,NAT16,TNS2,CYB561A3,ITGB3BP,SLC44A1,TMEM9,BHLHB9,BEX4,TP53BP1,ZNF346,PDSS1,NEIL2,TRPS1,SSBP2,EIF4ENIF1,CLEC2L,LMF1,XPO1,ZIC1,ZNF711,TRIM9,TCEAL7,TMEM237,FSTL5,SLC30A3,LINC02210,RNF103,MSRB3,TTC7A,FRMD6,IFT88,ST8SIA2" MicroRNA hsa-miR-1231:mirSVR_lowEffct hsa-miR-1231:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-110 6.22E-107 3.68E-109 3.39E-108 285 1633 "ACADM,CLK4,KDM5D,XKR4,NDRG3,ADCY6,ADD1,KIAA1211,SLC24A4,MTUS1,OSBPL8,ZNF578,ADGRF5,FAM135A,ZNF687,AMPD2,PHF12,NUMB,ATP6V0A1,BACH1,ADGRB2,LINC00847,BMPR1B,ARHGEF7,JAZF1,CACNA1A,CACNA2D1,CALB2,CAMK2A,VXN,SPAG9,NFS1,ZNF501,USP6,MAGI1,CLGN,CACNA2D2,COPB2,FOXN3,NDST3,SULT4A1,SRP14-AS1,LY86,IGLON5,ARHGEF6,FAM149A,AKAP6,SLC4A8,TOGARAM2,SEC31B,HAPLN1,CRY2,HINFP,ANKRD44,GDA,CLIP3,SNCAIP,RGS6,SEC24C,VCAN,PDE4DIP,DOCK4,GAPVD1,TCAF1,ARHGAP24,EARS2,ZNF337,IST1,DGKB,DAPK1,PITPNC1,ELMO1,MFAP3L,FBXL5,GSDME,PLPPR4,SNAP91,SPOCK3,SGSM2,DLX1,PDCD6IP,E2F5,EDN3,EDNRA,EDNRB,PHC2,EBI3,EGR3,AASS,GOLGA7,PLEKHA1,TNK2,CERCAM,DCTN4,EIF1,DENND4A,ZNF549,SIRPB1,KATNAL1,MRVI1,EZH1,CLVS1,TBC1D16,CHST15,FKTN,GORAB,FER,SPSB4,POLK,SUCO,MEX3B,HPCAL4,FLNC,PSD2,DOT1L,ABLIM2,IP6K3,USP19,GLYR1,MSL3,ZNF638,LUZP2,FERMT2,LILRB4,GPD2,GPR12,BTN2A1,ZBTB49,ADAMTS6,RASSF8,HAS2,UBE2QL1,ATXN2L,LRRC75A,GAREM2,KIAA1755,SCIN,IL6R,FAM69A,INPP5B,INSM1,NME9,KCND1,KCNJ16,KCNK3,KCNN3,CREG2,L1CAM,LAMA2,STMN1,HECTD2,GPR155,LYPLAL1,MBNL1,MEIS1,KCTD6,PPM1L,AFF1,GIT1,BLOC1S2,ADAM22,LAYN,RTL5,MYT1,NF1,NME4,SMIM11A,NTRK3,OCRL,CHAMP1,CLDN11,P2RX7,DPY19L2P2,PDE4D,DUSP26,SERPINI1,TMIE,PIK3R1,ZNF655,PLCL1,PLEC,PLIN1,PNMA3,PMP22,ING3,POLR2F,POU6F1,PRKACB,PRKCB,MAPK3,MAPK10,MASP1,PTPRB,PTPRD,ZNF844,FAM66C,SH3TC2,FAT4,RGS12,RNH1,CARF,ROBO2,CCDC102B,NEK11,ATP8B4,ABCA11P,HUNK,CLIP1,FAM192A,CSRNP3,ATXN2,SCN8A,SMPD3,CASC3,SH3GL3,MYO18A,ST6GAL1,WDR37,ABLIM3,SLA,FAM81A,SEPHS1,SLC8A1,RADIL,CCDC88A,ARFGAP1,SMARCC2,CDK5RAP2,RCOR3,FAIM2,KDM3A,SP2,GLT8D1,KDM4C,PEG10,IQSEC2,ATP10B,ITPRID2,ZNF302,SSTR2,NKAIN2,ERBIN,ST5,ELOVL4,SEPT8,KANK1,SULF2,VPS13A,NUDT10,PLCB1,SYP,SYT1,TBL1X,TRIM2,PCDHB9,USP32P1,ARHGAP9,GPRIN3,AP4E1,AKTIP,BHLHB9,NR2E1,SMUG1,TRPM2,SSBP2,TTTY15,SGK3,RPL7L1,MTCH1,PLPPR2,VLDLR,ZIC1,LYPD6,ZBTB38,EML6,SPIRE1,DNALI1,EVI5,LINC02210,SEMA3B,KCNAB1,FAM47E,RGS7BP,JMJD1C,NETO1" MicroRNA hsa-miR-34a*:mirSVR_lowEffct hsa-miR-34a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-110 6.22E-107 3.68E-109 3.39E-108 303 1845 "CLK4,ACTN1,NDRG3,ADD2,RNF150,KLHL13,TBC1D14,OSBPL8,HFM1,SPOP,SRPX,PCDH10,UNC79,FAM135A,GPRASP2,AMT,ZFAT,OGT,MAP4K3,BCAS1,TNRC6C,USP37,PPP4R4,TMEFF1,CDK13,PCDHGB4,ZBTB10,NCOA1,ATP2A2,ATP6V1G2,TTLL9,BCL7A,DST,SYNJ2,ARHGEF7,WASF1,IL33,CALB1,CAPN3,CAST,CDH2,LRRFIP1,DLGAP1,NRXN3,PPT2,C4orf33,QKI,TMEM184B,SRP14-AS1,ARHGEF6,CNTN1,ZFP28,NRG2,PREPL,CSF1R,ARHGEF10,OSBPL3,SOCS5,SLITRK5,PHF14,PUM1,RUBCN,KCTD8,DGKB,TMEM170A,ZNF804A,MFAP3L,TMCC2,WDR20,DLX1,DMTF1,ACOT8,DTNB,DNM1L,E2F5,EDN3,EDNRB,FAM13A,KMT5B,CALCRL,VPS13B,LRRC17,EPHB1,ZNF549,ETV1,RASL12,NRN1,F5,FAM198B,TAOK3,FCGR3A,OLFM1,FGF12,FGF13,TMEM164,SUCO,UBE2E3,IP6K2,SYNCRIP,C2orf88,EFCAB2,PDLIM5,TPK1,CAMKK2,KHDRBS3,CELF1,MSANTD4,SARAF,OGA,FYN,ZMAT1,GABBR1,CHL1,TRAF3IP2,FAM120B,MTHFD2,KIAA1841,ADAM28,USP19,HPGDS,TOX3,TNRC6A,MSL3,ZNF638,ADGRA3,GPD2,PRUNE2,FUT10,CCDC184,STON1,GPR37,RNF165,AP4S1,FAM107A,RASSF8,UBE2QL1,ARHGAP36,MIER3,AGBL5,ZDHHC15,NEGR1,TCEAL6,CELF5,NKD1,SCIN,KCND1,KTN1,LAMA2,LMO2,SYTL4,HECTD2,PIK3AP1,ZFYVE27,MAP2,MAPT,MBNL1,ADAM11,LRP1B,MID1,PPM1L,N6AMT1,MYCN,NEXMIF,TCEAL5,BEX5,NEK1,NF1,NFE2L2,NNAT,NOVA1,SLC11A2,OGG1,CLDN11,PCDHGC3,PCDH9,PDE4A,ENPP2,SEMA5B,PIK3C2A,TMIE,ZNF655,FAM218A,XRN1,PLCL1,PMP22,MAPKAP1,LRP12,EXOSC10,ING3,EPB41L4B,DRAM2,PPP3CC,PRKCB,VPS13C,ANKHD1,TMEM260,STK32A,PTPRB,STRC,FAT4,RAP1GDS1,RASGRF1,RBBP6,KHDRBS2,RFX3,RGS3,RGS12,MRPS18A,KLHL11,PBRM1,ZNF532,PCMTD2,FBXW7,BAALC,SPIN3,ATP8B4,ZNF331,TRAPPC13,AP1AR,SATB1,ATXN2,ATXN7,SCP2,MRAS,TRA2B,FRMPD1,CHD9,SYBU,SLA,KANSL3,PKNOX2,SEPHS1,KBTBD4,CPEB4,MYH15,SNAP25,KDM4B,DOP1A,PDZD2,DOK5,ZSWIM8,PEG10,ZC3H13,ZSCAN29,CEP68,STAC2,SYNE2,PLCB1,TACR1,PJA1,TAF9,ALG1,KIAA1107,TCF4,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,PCDHB10,NSD1,GPRIN3,SLC35G2,DICER1,ITGB3BP,AKTIP,SLC44A1,CDK20,NPL,NEIL2,TRPS1,PRR18,CLHC1,EIF4ENIF1,UCHL1,FLRT2,CCDC14,TBC1D15,WIPF1,GUSBP1,CFAP298,SLC47A2,ZIC1,ZIC2,KCNT2,REEP1,EMSY,KCNAB1,PDSS2,JMJD1C,TIGD6,KLHDC1,IFT88,LAS1L" MicroRNA hsa-miR-1226:mirSVR_lowEffct hsa-miR-1226:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-110 7.94E-107 4.67E-109 4.30E-108 307 1895 "VWA5B2,RALGAPA1,ASPHD1,SYS1,KDM5D,NDRG2,ADD1,PLEKHH1,PWWP2A,KIAA1211,INTS2,HACE1,OSBPL6,AK2,MARCH4,UNC79,FAM135A,AMPD3,DPP10,ANK2,EP400,C6orf89,MAP4K3,APBA2,EPB41L5,FAM131A,VAT1L,LGR5,SPTBN4,ZFYVE28,ARHGDIG,ARNTL,PCDHGB4,ATP2A2,ATP6V0A1,LINC00847,GPR146,KSR1,ARHGEF7,BTK,CACNA1G,C5,GPC2,CFAP410,CA12,CACNA1A,KALRN,HAP1,PTBP2,CAPN3,HIP1R,ARHGEF25,CBR1,CBS,CD86,CD38,ENTPD6,LRRFIP1,LARGE1,SRSF11,CNOT8,FBXO7,MAP4K4,IGLON5,TOGARAM2,RBM39,CRMP1,GDA,ABCG1,AATK,SNCAIP,CSF1,RGS6,OSBPL3,SIPA1L1,VAC14-AS1,PDE4DIP,PPP6R2,DCAF4,ZFYVE16,ZNF337,IST1,TMEM170A,SPATA2,TIAM2,RUSC2,GSDME,RHOBTB1,TMCC2,DLX1,CD99L2,DMTF1,DTNA,TOM1,DNAJB6,PHC2,ELN,CALCRL,LRRC17,RASGRP2,ENPP6,STX2,SRRM1,ERBB2,ZNF549,DNAJC27,RASL12,SIRPB1,KATNAL1,REEP2,TUBB3,DLC1,ST3GAL6,CHST15,FER,FGFR1,PCYOX1,SYT3,COQ5,POMT1,HVCN1,TVP23A,MEGF10,GALC,B4GALNT1,ZNF274,DISC1,GCNT2,TUBGCP4,SULT1C4,PPARGC1A,TXNL4A,GLYR1,TOX3,POLL,DCLK2,LOXL3,GPD2,MCHR1,GPER1,ATP2B1-AS1,PLCD4,ZNF496,ZBTB49,MUM1,NXPH3,FRMD5,SYNPO,IDH3B,GAREM2,ZIC5,SLC6A17,NME9,ITGA7,JAK2,KCNB1,KCND1,KCNN2,STXBP5,MAP6,SRSF12,PPM1L,MITF,XRRA1,MYO7A,MYO9A,BEX5,SFR1,NEFM,CCDC13,NFE2L2,NME4,NTRK2,OPA1,OPRL1,PCDHGC3,NALCN,PLCB2,PLXNB1,LRP12,PSAT1,EXOSC10,ING3,SEPT4,POLG,POLR2F,PCDHB17P,NDUFS7,WBP1L,WDR25,PIGG,PTCH1,ANKHD1,TMEM260,PTPRD,CASTOR1,PTPRO,TMEM255A,FAM66C,ZCWPW1,RADX,TRIM68,RGS12,RIC8B,RNASEL,C12orf49,CYB561D1,ROBO2,MCMBP,SGSM1,HSD11B1L,RTN1,ZNF568,ZNF331,SALL1,SBF1,CASC3,MRAS,FAM102A,MYO18A,FNDC3A,BTBD3,PKNOX2,ZNF430,SLC9A5,SLC14A1,ARFGAP1,SMARCC2,SNCA,SNRPN,FAM126B,DOP1A,IZUMO4,CLASP2,TROVE2,SSTR2,ERBIN,MPRIP,CEP68,RGL1,DIP2A,SEPT3,JMJD6,SYNE2,TMEM150C,SYP,MLST8,DNMBP,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,NAT16,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,DICER1,ZFPM2,ITGB3BP,MTMR14,TMEM9,TLR4,ERCC6L2,TPM1,WBP2,TRO,RUSC1,ZKSCAN5,UBTF,GORASP1,OSBP2,BCL2L13,WIPF1,LGI4,ZNF711,ZNF24,ZNF74,NDRG4,EML6,SH3GLB2,DHX33,DNALI1,GDPD5,LINC02210,ADAMTS9,SEMA3B,SIGLEC10,CASC15,ADAMTSL3,TTC7A,FAM198A,JPH3" MicroRNA hsa-miR-499-5p:mirSVR_lowEffct hsa-miR-499-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-110 1.17E-106 6.84E-109 6.30E-108 285 1637 "ABR,KDM5D,KLHL32,TMEM132B,AXIN2,USP31,ZNF608,SORCS2,ARHGAP20,CARNS1,ZFAT,FGD2,PHF12,APC,EPB41L5,USP37,LGR5,TMEFF1,ZBTB10,ATP2A2,BACH1,KSR1,BMPR1B,SYNJ2,ARHGEF7,JAZF1,PRMT9,C5,CFAP410,DDR1,CACNB4,KALRN,RGN,MTMR7,LRBA,CDH2,DCLK1,LOC730101,NDST3,CLTC,FBXO7,ABCG2,MAP4K4,IQCK,AKAP5,ABI3BP,RCHY1,TBPL1,RTTN,ZNF521,NRG2,RBM39,GDA,RGS6,SOCS5,VAC14-AS1,CNTNAP2,PLXNA4,FAM169A,DZIP3,PLCXD3,RIMS2,BOC,DOCK4,ARHGAP32,ZFYVE16,ZNF337,TM9SF4,MAML1,SCRN1,YTHDC1,FBXL5,KIAA0319,ZC3H11A,GRIN3A,DMD,DPP6,DTNA,TOM1,WDPCP,KLHL5,TMTC1,MRO,EIF4G1,IRAK4,RGS17,CALCRL,RCAN2,IGSF6,NSRP1,TAOK3,FKTN,SLC9B2,FGF13,SUCO,UBE2E3,MEX3B,PCYOX1,SYNCRIP,FLT1,NELFCD,FAM49B,SARAF,MEGF11,MEGF10,B4GALNT1,ERAP1,IGSF5,MSTN,WASHC2A,PCDH17,TCERG1,GLI2,GLYR1,ZNF638,GNAL,GNAO1,GPD2,PRUNE2,GPR12,PCLO,GRIA2,BVES,PSIP1,FAM107A,ADAMTS6,MAP4K5,BACH2,GABARAPL2,HNF4G,IGFBPL1,CELF5,IGF1,IL6R,IL6ST,LRRTM1,SLC35G1,METTL21A,KCND2,KIFC3,IPO5,STXBP5,KTN1,LAMP2,LMO2,MARK3,MATN2,MBP,LRP1B,KITLG,MPP2,ZNF680,BLOC1S2,NRBP2,N6AMT1,MYO6,MYO9A,NEXMIF,NCAM2,NELL2,SLC11A2,NRCAM,CHAMP1,PAX6,PCDH9,PDCD2,NLGN3,SEMA5B,CCSER2,XRN1,MAPKAP1,STRN3,LRP12,PSAT1,ING3,EPB41L4B,MINDY2,MAPK10,HYDIN,PIGG,CNTLN,ANKHD1,PTPRG,PTPRO,PPP2R3C,CEP97,FAT4,FAM184A,ENOX1,RADX,RFX3,RGS3,RGS12,RIC8B,PBRM1,ALG9,ROBO1,RPL15,ATP8B4,LRRK2,MEG3,RMI1,SALL1,SATB1,FNIP1,GALNT10,SUPT20H,HSPA4L,ZFP30,KIF21A,PPM1E,FBXO11,SEC31A,WDR37,FAM81A,EPN2,CCDC88A,ELMO2,LMBRD1,USP33,DOP1A,SOX11,KDM3A,SP4,ARHGAP26,ZBTB43,SPART,ATP10B,CAMTA2,POGZ,ZC4H2,NEK4,TTBK2,RGL1,KANK1,PRRC2C,NUDT10,DNAJC9,SYN2,MTCL1,CAMTA1,DNMBP,FAM208A,KIAA1107,SATB2,TRIM2,TCF12,DOCK9,PHF24,PCDHB3,NSD1,GPRIN3,HIF3A,SIRT1,C18orf54,SLC44A1,ARL10,TK2,ACTR6,ERCC6L2,KAT6B,TP53BP1,TRO,TRPS1,PPIL6,UBE3A,UGT8,ZNF709,RICTOR,XRCC4,ZIC1,ZNF24,MICU3,ZNF28,POLR3H,ANKS1B,SPIRE1,INTS3,EMSY,SLC38A1,EVI5,WNK3,AMN1,PHTF2,FXR1" MicroRNA hsa-miR-432*:mirSVR_lowEffct hsa-miR-432*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.39E-110 1.34E-106 7.76E-109 7.14E-108 271 1479 "ABCF1,SYN3,ACTN1,NDRG3,TMEM132B,RNF157,ADORA2A,AP2A1,AP2A2,MTUS1,RTL9,SPOP,FAM135A,ZFAT,OGT,SEMA7A,PI16,APC,APLP1,LGR5,ARHGDIA,PCDHGB4,ATP1A1,ZNF583,ATP6V0A1,BACH1,CFLAR,HAP1,PTBP2,CAMK2B,SPAG9,NFS1,CBR1,MTMR7,ZBED1,LOC730101,UBE2L6,FOXN3,ARHGEF6,CNTN1,ABI3BP,COX4I1,SMARCAL1,ZNF385A,CLOCK,PREPL,CREM,NCOR2,GDA,CSF1,RGS6,SOCS5,CNTNAP2,CYBB,KATNAL2,ZNF337,MATR3,GIT2,ARMCX4,PITPNC1,ARMCX2,YTHDC1,ELMSAN1,MFAP3L,TMEM130,DDX46,ALKBH8,SV2B,WDR20,GRIN3A,CASP8AP2,TOM1,EDN3,CNNM1,HEYL,ELN,C3orf18,TMEM35A,EPB41,ZNF549,SPEG,CDKL3,MRPL10,DLC1,CEP78,FCGR1B,CHST15,FKTN,FGF11,BAIAP2,TMEM164,AMOTL2,POLK,AGAP3,SEMA4D,FLT1,SLC37A3,FLYWCH1,NELFCD,EFCAB2,PDLIM5,CAMKK2,MEGF10,GABBR1,HRASLS5,GABRG2,DISC1,CPLX2,ALDH1L1,TUBGCP4,ADAM28,TTBK1,GLI2,GLUL,ZNF638,GNG4,CCDC184,TMEM121B,CACFD1,GRM2,RNF165,AP4S1,RABL2A,IRAK3,RASSF8,PADI2,NXPH3,HLF,HSF2,SHISA6,CELF5,KIAA1755,KCNN3,LMO2,ZFYVE27,PPM1L,MMP16,MPP2,GIT1,MYO7A,NEK1,VWA2,PCBP3,NRCAM,NTRK3,PCDHGC3,PCSK5,PDE4D,TMIE,CCSER2,SNX10,RETREG1,PKM,KCTD15,SDK2,POLR2F,PPARA,PPP3CA,NKAIN4,RANBP3L,PRKAB2,CEP41,MAPK10,DIRAS2,BCAS3,TMEM104,BDNF-AS,MTMR10,TMEM260,PTPRB,PTPRE,NKAIN1,PID1,USP47,RAP1GDS1,RASGRF2,RADX,HKR1,ZMAT4,RET,RGS3,GSTCD,ROBO2,CCDC102B,NEK11,TCP11L1,STK32B,LRRK2,ATAT1,DGLUCY,ATXN2,SCP2,MRAS,PPM1E,SLA,FAM81A,ARHGEF40,ELMO2,SLC22A4,SMARCD3,RCOR3,KIF13A,CABCOCO1,SNRPN,KDM4B,TSNAXIP1,ZSWIM8,ZNF423,DBNDD2,RBM26,NFASC,PBLD,POGZ,ITPRID2,NSFL1C,VPS13A,TACR1,TAL1,ALG1,SMG6,WSCD1,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PCDHB9,PUM2,FRYL,ZFPM2,GALNT17,TMEM9,ICAM5,ERCC6L2,TPM1,CDK20,RGMB,ZNF346,PDSS1,TSN,SGK3,LINC00689,RBFOX3,WIPF1,GUSBP1,ZNF17,ZNF23,ZNF24,ZNF70,NDRG4,TMEM237,EMSY,ADAMTS9,FAM47E,PDSS2,FZD3,TMEM63C,CASC15,FAM219B,MSRB3,LAS1L,PRRT4" MicroRNA hsa-miR-3174:mirSVR_lowEffct hsa-miR-3174:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.89E-110 1.62E-106 9.34E-109 8.60E-108 283 1616 "ABCF1,AS3MT,PSMG3-AS1,KIAA1211,PTCHD1,ADRB2,KCTD16,RTL9,KIAA1324,UNC79,ZNF687,ANK2,MAP4K3,PPFIA3,IGDCC4,SPTBN4,PLA2G4C,ATP2B2,ATP6V0A1,TTLL9,MPDZ,SEC11C,BCL7A,NRP2,CFLAR,BTK,C5,CA4,CA12,CALB1,KALRN,CAMK2G,VXN,ISPD,SPAG9,RGN,ARHGEF1,FOXN3,CPNE6,RAB28,NRXN3,TPP1,CLTB,SRP14-AS1,RAB26,CNTN1,ARMC8,AKAP6,LETMD1,MYRIP,PREPL,CRMP1,AATK,SNCAIP,CSNK1G3,FAM169A,KIAA0040,APPL1,PNPLA8,ZSCAN23,KIAA0408,BOC,SNPH,ARHGAP24,HDAC4,TM9SF4,SCRN1,AIF1L,PITPNC1,ZBTB24,RHOBTB1,DMD,DYNC1I1,PDCD6IP,DTNA,ECM2,EDIL3,EDNRB,CNNM1,SEMA3D,FAM13A,KMT5B,AASS,IRAK4,C8orf37,EIF1,EMX2,ENO2,ETV1,EZH1,NRN1,F5,FAM198B,ZNF461,RPS6KC1,FCGR1A,SLC9B2,FHL1,FOXF2,PCYOX1,SYNCRIP,FOXO3,C2orf88,JKAMP,ZBED3,ATP6V1H,ZNF605,ERGIC3,CSPG5,NSG1,MSANTD4,TVP23A,OGA,MEGF11,B4GALNT1,SULT1C4,GHR,BRD8,ZNF638,GNAO1,ZNF782,PCLO,STMN2,ADAMTS6,HAS2,DDX19B,CPT1C,RBPJ,ZNF678,INPP5B,ITGAM,KCND2,KCNN2,TTYH2,LIMS1,LRP1B,MEIS2,AFDN,ADAM22,PTOV1,HS6ST3,LYRM9,ZC3H12B,NEFM,NFYA,NINJ2,NOVA1,NPTX2,CLDN11,P2RX7,PAX6,PCDH9,PCSK5,CDK18,PDCD2,PDE4D,GPR85,PIK3C2A,XRN1,PKM,FAM216A,JAKMIP1,SMIM7,ZNF426,PNMA3,SCHIP1,RETREG2,EPB41L4B,POU6F1,PPP2R2C,PPP3CA,CEP41,PRKAR1B,CNNM2,SAMD9,BCAS3,CYBC1,SNRK,ELOVL2,TMEM260,PTPN13,PTPRD,EML5,NKAIN1,PID1,FAM66C,TRIM68,DPF2,RET,REV3L,ERI2,RFX2,MRPS18A,RIC8B,ROBO2,CCDC25,PCMTD2,NEK11,ATP8B4,GLDN,SGSM1,ADAL,TCP11L1,ABCA11P,RYR3,SALL1,SEMA6D,SCN2B,TNFRSF19,SEC14L1,MRAS,ASAP3,MYO18A,FNDC3A,R3HDM2,WDR37,ARHGEF40,SLC12A2,ELMO2,INAVA,SNAP25,SNCA,BDP1,DOK5,SPP1,ERC1,LMO3,ITPRID2,ZC4H2,KLHL7,SYNE2,VPS13A,ADAMTS17,SYN2,COBL,TACC1,TACR1,MTCL1,CAMTA1,TAL1,PDLIM2,ADGRL3,TBL1X,TCEA1,DMXL2,TRIM2,DOCK9,PCDHB6,ARHGAP9,PCDHA5,HIF3A,DICER1,DICER1-AS1,C18orf54,ITGB3BP,MTMR14,NR2E1,WBP2,ZNF346,PDSS1,AMACR,STXBP4,BCL2L13,VIPR2,RICTOR,XPO1,ZBTB14,MICU3,ZNF28,ZBTB38,REEP1,TMEM237,EML6,SPIRE1,MEIS3,SLC30A4,NT5M,ADAMTS9,GAL3ST3,FZD3,FBXO36,GAN,CPNE4" MicroRNA hsa-miR-148a:mirSVR_lowEffct hsa-miR-148a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.80E-110 2.69E-106 1.54E-108 1.42E-107 302 1843 "KCNH8,ASIC1,ACHE,NCKAP5,ADD2,PLEKHH1,USP31,PWWP2A,DPY19L2P4,MTA3,SLC24A4,OSBPL1A,CC2D2A,HFM1,SRPX,ARHGAP20,SYT13,ZFAT,OGT,ANK2,CCDC146,EPB41L5,TNRC6C,USP37,LINC00173,CDK13,MARCH3,NUMB,ATP2A2,ATP6V0A1,BACH1,MPDZ,BID,KSR1,MTMR2,CACNA1B,DDR1,CALM1,KALRN,CAMK2A,LDB2,USP2,SEPT7,CDC25B,TIGD7,TBRG4,CLCN3,TPP1,CLTC,FBXO7,FAM189A2,MAP4K4,CNR1,IQCK,PCYT1B,LETMD1,SLC35F1,CS,CSF1,PDE4DIP,PLXNA4,PPP1R16B,APPL1,PHF14,CCDC144A,KATNAL2,DCAF8,TBC1D5,ARMCX4,ARMCX2,SPATA2,ELMO1,RHOBTB1,USP3,DNAH9,SLC29A4,CDON,SLC12A6,DPYSL2,ACOT8,PDCD6IP,DNAJB6,ABCC5,WDPCP,EDNRA,EDNRB,HEYL,CELSR3,APH1A,EGFR,KMT5B,RASA4,AASS,EIF4G2,PAN3,EPB41,EPB41L2,MTSS1L,GPHN,SLC43A2,STX2,TAOK3,ST3GAL6,FCGRT,FDFT1,OLFM1,AMOTL2,SCARA3,SEC23B,FOXF2,SEMA4D,NOP56,NBEA,PDLIM5,ZNF605,GALNT15,GALC,SIGLEC8,SEPT9,ALDH1L1,TUBGCP4,RNPS1,SPIN1,TOX3,AIFM3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,ADAMTS13,SERP2,GRM2,ZNF496,LINC01089,FAM19A2,RASSF8,FRMD5,PACSIN2,HLF,SYNPO,HNMT,AGFG1,ICA1,ZNF546,IGF1,INPP5B,SLC35G1,KCNJ16,A1BG-AS1,PIK3AP1,ZFYVE27,MAP4,AQP11,MBP,CHIC1,MEIS1,MKLN1,MMP16,COMMD5,NEXMIF,NACA,NELL2,NFYA,NOVA1,NTRK2,TBC1D25,OPA1,P2RY1,GPR137C,DPY19L2P2,PCSK5,PRTG,PDE4B,PDE4D,PIK3R1,SNX10,PKM,GPSM2,NLE1,MTRF1L,PRIMPOL,LRP12,ING3,MBOAT7,SH3KBP1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,EPDR1,MAPK9,HYDIN,MASP1,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,ROGDI,RBBP8,PRRT2,RFX3,RIC8B,ZNF532,BAALC,ZC3H14,CLIP1,RTN1,SEMA6D,CSRNP3,SCN2B,SCN8A,MRAS,SUPT20H,TRA2B,RASA3,MYO18A,AMBRA1,SYBU,SLA,EPN2,DHX30,KANSL3,PKNOX2,SLC8A1,ARHGEF40,CCDC88A,TRIM67,SLC12A2,BTBD7,CPEB4,RCOR3,IFT122,SNAP25,SNCA,KIF13A,FAM126B,MYO16,PDZD2,BDP1,KDM4C,TEX2,CLASP2,CLSTN2,ERBIN,STAU1,DIP2A,STXBP1,PRRC2C,PLCB1,TMEM150C,SYT1,C12orf76,TAF9,EXOC7,TAL1,AGTPBP1,FBXW11,TCF4,ZFP90,NAT16,DOCK9,PHF24,PCDHB4,GPRIN3,MTMR14,NR2E1,R3HDM1,CDK20,SYNPO2,METTL3,TRPS1,HIRA,UBE3A,UGT8,OSBP2,FLRT2,ZNF709,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,CADM2,SLC38A1,KCNAB1,FAM47E,PARP11,UBE3B,KAT6A,CASC15,FAM219B,FAM198A" MicroRNA hsa-miR-1912:mirSVR_lowEffct hsa-miR-1912:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.83E-110 2.70E-106 1.54E-108 1.42E-107 292 1724 "CLK4,NCKAP5,KLHL32,ADCY6,ADD1,PWWP2A,RNF150,PTCHD1,BEND6,AP2A2,WDR35,CC2D2A,SEMA6A,SPOP,PCDH10,EP400,APBB2,VAT1L,USP37,SFMBT2,IGDCC4,LINC00173,MARK4,NUMB,CCAR2,ATP1A1,N4BP2L1,DPY19L3,CARMIL3,ADAM15,CFLAR,PROM1,KSR1,BMPR1B,SYNJ2,CACNA1G,GPC2,RAB29,CFAP410,CACNA1B,CALB1,PTBP2,CAMK2B,KYAT1,CCNH,P2RX6,CBFA2T2,CD38,LRBA,ARHGEF2,MAGI1,NOG,SOCS6,CHN1,CHN2,DGCR9,CLTC,QKI,MAP4K4,ARHGEF6,AKAP7,ARMC8,AKAP5,SLC4A8,RCHY1,TOGARAM2,MYRIP,IGDCC3,CDC42BPB,HAPLN1,ANKRD44,TRIM69,LRIG1,GALNT9,PDE4DIP,PPP1R16B,ERC2,SEC14L5,MYADM,KATNAL2,ARHGAP24,ZNF337,RASSF2,KIAA0586,SPOCK2,TIAM2,GUCD1,SGSM2,CHRDL1,GRIN3A,DMPK,NR1D2,CDON,ECM2,TOM1,DNAJB6,ABCC5,DNM1L,SNX29,EDNRB,ANKRD46,SUGP2,MRO,MBNL2,USPL1,EPB41,COQ7,RCAN2,SPEG,VPS26C,ANKMY1,REEP2,CLVS1,DLC1,FCGR1A,PPP1R1B,GTF2IRD2,FGF1,OLFM1,BAIAP2,PRKAG2,SUCO,MEX3B,PCYOX1,AGAP2,SYNCRIP,NOP56,C2orf88,SMC2,PDLIM5,KIAA1841,GATM,NEU3,ALDH1L1,GCNT2,ADAM28,GFRA2,PCDH17,GHR,PPARGC1A,COPS8,MSL3,PRUNE2,CCDC184,PCLO,PLCD4,SERP2,RNF165,KAT7,ZBTB49,BVES,MAN1B1,FRMD3,TNFAIP8L3,BACH2,MIER3,AGFG1,SHISA6,IDH3A,IDH3B,C2orf72,IL6ST,SLC6A17,ITGAM,GPR62,KPNA5,LAMP2,STMN1,SYTL4,ZFYVE27,LRP1B,MGAT3,ZNF680,MSI1,MYCN,MYH3,MYO9A,NEXMIF,SFR1,NF1,NFIX,SLC11A2,NRCAM,NTRK2,NUCB2,LOC100128398,PCSK5,PDE4D,PFKFB2,NALCN,ZNF655,PSAT1,ING3,RETREG2,MBOAT7,FA2H,SH3KBP1,PPARA,RANBP3L,GRAMD1C,RELN,GDPD2,QRICH1,PIGG,ELOVL2,TMEM260,PTPRB,FAM66C,ZDHHC14,TRIM68,PRRT2,RGS12,ZNF532,EXD2,ALG9,ARMC5,CARF,PCMTD2,MRAP2,FBXW7,BAALC,ATP8B4,ABCA11P,KCNIP3,SCP2,TNFRSF19,TRA2B,PUF60,ASAP3,MYO18A,FBXO11,PPP4R3A,SLC9A5,SLC11A1,ELMO2,ZKSCAN3,SMARCD3,IFT122,SNRPN,TMCC1,PDZRN3,MYO16,RBM34,NMNAT2,CDK19,ZBTB43,TSPYL2,ZNF621,ATP10B,POGZ,SSTR1,MPRIP,ZSCAN29,TTBK2,RGL1,DIP2A,NSFL1C,ARHGEF9,VPS13A,SYN2,MTCL1,PDLIM2,TRIM2,CLASP1,CCDC173,SIK3,DICER1-AS1,RIMBP2,RGMB,SYNPO2,ELP5,STXBP4,EIF4ENIF1,PLEKHH2,RICTOR,ZIC2,TMEM198,ZFAND5,GDPD5,LINC02210,ADAMTS9,MDH1B,URM1,SLC17A7,KCNAB1,RGS7BP,DOCK8,FAM219B,JMJD1C,RNF170,TTC7A,IFT88" MicroRNA hsa-miR-1264:mirSVR_highEffct hsa-miR-1264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.96E-110 2.78E-106 1.58E-108 1.45E-107 289 1689 "ABCF1,KCNH8,ACADM,CLK4,FMNL2,KIAA1211,PTCHD1,INTS2,OSBPL1A,AK2,ADGRF5,ALCAM,SRPX,ARHGAP20,FAM135A,OGT,CDC42BPA,LRCH2,CCDC146,LCORL,BCAS1,PPP4R4,TMEFF1,CDK13,STK33,ATP1B3,ATP2B2,DPY19L3,ATP6V1G2,KIF1A,ADGRB3,CFLAR,SYNJ1,ST3GAL5,FUBP1,SCAPER,MTMR3,JAZF1,CA8,CACNB4,THSD7A,KALRN,CAMK2G,CLDN10,ZMYM4,L3MBTL4,MAGI1,SRSF11,CNOT8,SLIT2,NRXN3,TPP1,QKI,ARHGEF6,CNTN1,AKAP7,COL4A5,SLC4A8,AHCTF1,CNRIP1,SLC35F1,FAM171B,HAPLN1,HINFP,CLIP3,CS,SIPA1L1,SOCS5,PDE4DIP,PLXNA4,UBXN2A,PHF14,CYBB,ARHGAP32,RIPOR2,TMEM170A,PITPNC1,ARMCX2,FBXL5,WDR20,CHRDL1,DTNA,E2F5,WDPCP,EDN1,EDNRB,CELSR3,FAM13A,EGR3,RASA4,STARD3NL,PAN3,DCTN4,USPL1,TUBD1,LRRC17,ETV1,F5,ARMCX1,CEP78,MED12L,FGF13,POLK,SUCO,SYNCRIP,SEMA4D,C2orf88,JKAMP,TMEM107,ZBED3,UFM1,PDLIM5,FAM49B,CAMKK2,ATP2C1,ZNF605,MEGF11,ZNF559,LRRC37A6P,KIAA1841,GATM,TUBGCP4,TUBA8,ARFIP1,SESN1,GGTA1P,GHR,PPARGC1A,MALT1,SPIN1,GLYR1,ZNF638,MAP7D2,DCLK2,GNAO1,TDRKH,GPR12,GPR34,DIDO1,FAM19A2,RASSF8,SMAP1,IRF8,MSL1,LRRCC1,FAM69A,INSM1,SLC35G1,KCNJ16,KCNN2,LINC00634,LAMP2,LMO2,SYTL4,HECTD2,NCOA7,PIK3AP1,MARK1,LYPLAL1,MAT2A,AQP11,LRP1B,MEIS2,SRSF12,MEST,MITF,ZNF680,MSR1,NRBP2,NCAM2,NDP,NF1,NFE2L2,SLC11A2,SMIM11A,GLIPR1L2,CNTN3,PCDH9,PDE1C,PDPK1,GPR85,CYTL1,GPSM2,NLE1,PLCL1,PLIN1,PCDH18,LRP12,SCHIP1,CCDC144B,PRKACB,MAPK9,GRAMD1C,SNRK,PTK2,TMEM260,TTC13,ZNF615,MARCH1,RAP1GDS1,MSANTD2,REV3L,FIGN,ZFHX4,EXD2,CARF,RORB,FBXW7,TCP11L1,MEG3,ABCA11P,KCNIP1,CLIP1,AP1AR,ATXN2,ATXN7,SCN7A,TRA2B,HSPA4L,ZFP30,SHMT2,HKDC1,FBXO11,FNDC3A,FHOD3,NLGN1,SEC31A,PPP4R3A,RADIL,BTBD7,RCOR3,PDZRN3,PDZD2,UHRF1BP1L,ZC3H13,SPTAN1,ZBTB43,SPART,ITPRID2,SAMSN1,ERBIN,NXT2,ZSCAN29,SEPT8,NECAB1,SYNE2,SLC37A2,FAM208A,KIAA1107,AGTPBP1,TBL1X,KLHL4,SATB2,CUX2,TCF12,CLASP1,DOCK9,PCDHB9,RNF216P1,ZFPM2,AP4E1,RIMBP2,TP53BP2,TTC3,SGK3,TUBB1,RPL7L1,FLRT2,CCDC14,ZBTB14,KCNT2,SPIRE1,LAMP5,SMARCAD1,SLC30A4,PRDM10,RNF103,HPS4,NAV3,KCNAB1,FAM47E,WNK3,DNAH10,FAM13C,RTN4,KAT6A,PHTF2,NLRP3,DPF3" MicroRNA hsa-miR-624:mirSVR_lowEffct hsa-miR-624:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.42E-110 4.15E-106 2.35E-108 2.16E-107 298 1798 "CLK4,NCKAP5,SYS1,KDM5D,TMCC3,AXIN2,BRAP,PWWP2A,ESYT2,ZNF608,WDR35,TXNDC16,ZNF578,ADGRF5,ALCAM,CARNS1,MARCH4,PCDH10,OGT,MAP4K3,BCAS1,SHROOM2,CDC14B,PPP4R4,CCAR2,TMEM108,SLC4A4,ZNF583,ATP6V0A1,SYNJ1,ARHGEF7,CASTOR3,PRMT9,GYG2,WASF1,CACNB4,CABP7,CAMK2B,CAMK2G,CH25H,ISPD,NFS1,PRC1,CBR1,ZNF501,LOC730101,CDO1,COPB2,ASIC3,ARHGAP22,PPT2,TPP1,C4orf33,QKI,MAGED1,ABI3BP,TBPL1,ZNF521,ZFP28,CREM,RBM39,CRMP1,GDA,SNCAIP,CSF1,LRIG1,CSNK1E,CSNK1G3,SOCS5,FAM169A,RIMS2,MYADM,ARHGAP32,KATNAL2,DCAF8,MATR3,KIAA0586,MAML1,SCRN1,DBI,DNAL1,RUSC2,RHOBTB1,SNAP91,DLX1,EXOG,NR1D2,CDON,CASP8AP2,TOM1,ABCC5,EDNRB,SEMA3D,TMTC1,EIF4G2,EIF5,COPS4,PLEKHA1,MRNIP,STARD3NL,EIF1,EPHB1,STX2,IGSF6,RRAGB,EYA1,NSRP1,DLC1,FKTN,KAT8,ZNF589,OLFM1,FHL1,ATP5PD,SYNCRIP,RGPD5,NELFCD,C2orf88,PDLIM5,MPP6,TVP23A,OGA,GABRB3,MTHFD2,C15orf41,DISC1,CPLX2,GCNT2,GFRA2,FREM1,PCDH17,GLI2,CBX1,GPD2,GPR34,PCLO,ZNF496,AP4S1,RABL2A,PSIP1,ADAMTS6,HAS2,DDX19B,ZNF491,ZDHHC15,USP51,NEGR1,LRRC75A,SHISA6,MYLK2,KCNJ5,KCNK3,KCNN3,KCNQ3,KIF2A,KIF5A,KPNA5,STXBP5,KTN1,MAP4,MAT2A,MATN2,MEIS1,MEIS2,N6AMT1,MYCN,NELL2,DNHD1,NTRK3,OXTR,P2RY1,PAX6,PCDH8,PDCD2,PDE4D,ENPP2,NALCN,PIK3C2A,ZFYVE21,PLCL1,PCDH18,PURG,PSAT1,RETREG2,FA2H,PPM1B,CCDC144B,NKAIN4,PRKAR1B,RELN,CNNM2,BCAS3,WDR25,PIGG,CNTLN,BDNF-AS,TMEM260,PTPN13,MARCH1,USP47,SUSD4,NWD1,ENOX1,MSANTD2,RDX,DPF2,RFX2,MRPS18A,SLC25A36,CCDC25,PCMTD2,MRAP2,MAP6D1,ABCA11P,CLIP1,RYR3,ZNF331,SATB1,ATXN2,SCAF8,SGK1,KIF16B,FAM81A,EPN2,CPEB4,CDK5RAP2,RCOR3,SNAP25,FAM126B,MYO16,KDM4B,FAM219A,PDZD2,MYCBP2,KDM4C,IQSEC2,ZBTB43,CLSTN2,ZC4H2,NKAIN2,ZSCAN29,SEPT8,TTBK2,NECAB1,SYNE2,ANKRD28,C12orf76,MTCL1,CAMTA1,EXOC7,TBCEL,TBL1X,TCF4,ZEB1,TRIM2,PCDHB3,NSD1,GPRIN3,FAM200B,DICER1-AS1,AP4E1,GALNT17,HEY1,ASXL3,NR2E1,CSMD1,TPM1,DOK6,RGMB,SYNPO2,KCNE5,TTTY15,HIRA,BCL2L13,CCDC136,WIPF1,LAT2,KLC2,RICTOR,KCNT2,LYPD6,CELF4,TMEM237,POLR3H,FSTL5,MAP3K12,EMSY,EVI5,RNF103,NAV3,MPPE1,WNK3,SMIM8,FAM219B,ADAMTSL3,KLHDC1,IFT88,CPNE4" MicroRNA hsa-miR-892a:mirSVR_lowEffct hsa-miR-892a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.75E-110 5.46E-106 3.07E-108 2.82E-107 296 1776 "VWA5B2,KCNH8,ASPHD1,AS3MT,PLEKHH1,CASKIN1,KCTD16,HACE1,WDR35,CC2D2A,SRPX,PCDH10,GPRASP2,AMPH,LRCH2,LCORL,MYH7B,PHF12,USP37,SHROOM2,SEMA4G,MARCH3,ZNF582,DPY19L3,BBS2,BID,SYNJ1,FUBP1,CASTOR3,MTMR2,SGCE,CACNB4,CABP7,CAST,PRC1,CCNH,CD86,ARHGEF1,DLGAP1,FOXN3,SOCS6,CHN1,NDST3,NRXN3,C4orf33,MAP4K4,FHL5,CNR1,CNTFR,IQCK,AKAP6,WHRN,MAGED1,ABI3BP,RCHY1,ZFP28,AKAP12,NCOR1,GDA,CSF1,OSBPL3,VAC14-AS1,KIAA0408,DOCK4,GAPVD1,DCAF8,DAPK1,ZBTB24,TIAM2,PLPPR4,SPOCK3,SEC16A,RAB39B,DMD,CASP8AP2,ARRDC4,ECM2,DUSP9,EDN1,EDN3,SEMA3D,YAF2,IRAK4,TNK2,CERCAM,MRNIP,EPB41L2,RCAN2,ENPP6,SRRM1,RASL12,MRVI1,F5,ARMCX1,TMEM132C,PTK2B,TAOK3,CORO2B,FCGR1A,FGF12,BAIAP2,TMEM164,FHL1,POLK,ATP5PD,RGPD5,IQCG,EVL,FLT1,EFCAB2,JKAMP,PDLIM5,TPK1,NSG1,AP4B1,ABLIM2,GABRB3,ZNF559,WASHC2A,ADAM28,PPARGC1A,MALT1,SPIN1,TOX3,LUZP2,DCLK2,GNAL,ZNF782,PRUNE2,LILRA2,PLCD4,CACFD1,BTN2A1,ZBTB49,SOX21,GUCY1B1,ATOH8,PADI2,DDX19B,MIER3,VSIG4,ZNF491,DHX35,LRRC75A,RBPJ,INPP5B,ITGA7,SLC35G1,KCND2,KCNJ16,LAMP2,LIMS1,MARK1,CHIC1,PPM1L,MN1,ADAM22,MYO6,RTL5,NEFM,NOVA1,DNHD1,SLC11A2,OCRL,CHAMP1,OXTR,P2RY1,PCDH9,PDE4D,OLA1,TMIE,ZFYVE21,MTRF1L,ING3,PPP1R1A,KANSL1,PRKAB2,CEP41,MAPK4,GDPD1,WBP1L,APTX,SNRK,PIGG,CNTLN,SPDL1,PTN,TMEM260,STK32A,PTPRD,PTPRO,NKAIN1,TUG1,TMEM231,PID1,RAD51D,ZNF793,ENOX1,HKR1,MSANTD2,ZMAT4,DPF2,PBRM1,CCDC82,CARF,PCMTD2,MRAP2,NEK11,FBXW7,SPIN3,LRRK2,STX1B,DGLUCY,TRA2B,KIF16B,ASAP3,FNDC3A,CCDC92,NLGN1,PPP4R3A,SLC6A11,KDM4D,SLC8A1,ARHGEF40,SLC11A1,SLC12A2,BTBD7,ATF7IP,OGDHL,SMARCD3,ANKRD36,SNAP25,MBD5,SNRPN,DOP1A,BDP1,SP2,ZSWIM8,HECW1,MYCBP2,TSPYL2,RBM26,DDN,NEK4,CEP68,DIP2A,SEPT3,ZC3H4,SYT1,TACC1,TACR1,ANKRD12,CAMTA1,TAF6,DNMBP,TRIM2,CLASP1,SLC19A3,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,TMEM9,TK2,ASXL3,RIMBP2,ZNF346,SYNPO2,TRIO,STXBP4,TSC1,SSBP2,TTC3,CLHC1,BCL2L13,VLDLR,TBC1D15,WIPF1,RICTOR,PCDH20,ZNF24,LYPD6,CELF4,ZNF154,POLR3H,EML6,SH3GLB2,SPIRE1,ZNF213,DHX33,CADM2,SLC38A1,STOX2,RGS7BP,NLRP3" MicroRNA hsa-miR-367:mirSVR_lowEffct hsa-miR-367:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-109 6.33E-106 3.54E-108 3.26E-107 296 1777 "VWA5B2,AS3MT,ELFN2,CCDC85A,UNC5A,PWWP2A,BEND6,MTA3,HACE1,OSBPL6,OSBPL8,TAOK1,PCDH10,UNC79,AMPH,LRCH2,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APBB2,MAGEE2,DDO,VAT1L,PPP4R4,CASK,RGS20,CDK13,MARCH3,NCOA1,SLC4A4,ATP1B3,DOCK11,BACH1,FUBP1,SLC16A4,L3MBTL4,DLGAP2,CLGN,PLAA,AKAP7,PCYT1B,ARMC8,ABI3BP,COX4I1,AHCTF1,MYRIP,ZNF521,SEC31B,C2CD2,CREM,AKAP12,CLIP3,AATK,RGS6,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,PPP6R2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,DGKB,SCRN1,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,WDR20,GRIN3A,NR1D2,DPP6,DPYSL2,MAMLD1,EDIL3,FAM13A,PHF20L1,EIF4G2,TENM1,STARD3NL,EIF1,EMX2,RCAN2,SRRM1,ERBB4,MRPL37,DNAJC27,EYA1,CLVS1,NSRP1,SCML2,DLC1,RACK1,FCGR1A,ST3GAL6,FKTN,ZSCAN30,GORAB,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,UBE2E3,MEX3B,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF10,GABBR1,MTHFD2,LRRC37A6P,KIAA1841,GATM,MSTN,ADAM28,PCDH17,DBF4,CBX1,DCLK2,PRRC2B,FUT10,GRM8,GSTT2,SOX21,GUCY1B1,IRAK3,ZHX1,HMGCR,ZNF491,NEGR1,TCEAL6,LRRC75A,EID2B,INSM1,JAK2,METTL21A,KCND2,IPO5,PAXBP1,HECTD2,PACRG,MAP4,MARK3,TM6SF1,MEST,AFF1,MMP16,MXI1,MYH3,NEXMIF,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,GLIPR1L2,PCDH8,PCDH9,PCSK5,PDE4D,PFKFB4,FAM218A,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,PPARA,PPP2R5E,RANBP3L,PRKAB2,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,ANKHD1,PTPRG,PEX2,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,RET,GTDC1,SLC25A36,ZFHX4,EXD2,ALG9,STK32B,LRRK2,RPS20,RYR3,ZNF331,SEMA6D,CSRNP3,ATXN7,SCP2,RASA3,SGK1,FERMT1,SHC4,CHD9,SYBU,ANKRD6,FAM81A,PPP4R3A,SEPHS1,ATF7IP,SMARCD3,MBD5,LMBRD1,DOK5,HECW1,ZNF423,TSPYL2,MCF2L2,RBM26,ZC4H2,SS18,ERBIN,SEPT8,DIP2A,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,DNMBP,KLHL4,ATMIN,TCF4,SIN3B,DMXL2,ZEB1,TCF12,NAT16,SLC19A3,SLC35G2,TEK,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,CSMD1,RGMB,PDSS1,STXBP4,TRPS1,TSC1,SSBP2,PLEKHH2,XRCC4,ZNF28,ELFN1,NDRG4,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,KCNAB1,AMN1,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NHSL1,NETO1,SENP7" MicroRNA hsa-miR-34b:mirSVR_lowEffct hsa-miR-34b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-109 6.47E-106 3.60E-108 3.31E-107 301 1837 "ACADM,SYS1,KDM5D,TMEM132B,CCDC85A,GALNT13,ADD2,BEND6,PCDH19,RTL9,WDR35,AK2,TAOK1,SMIM17,ALCAM,PCDH10,FAM135A,ALK,ZFAT,DPP10,MAP4K3,PHF12,SFMBT2,ARNTL,ZBTB10,TMEM108,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CA8,CACNB4,VXN,RUNX1T1,CERS5,DCLK1,ZMYM4,LARGE1,CACNA2D2,CFL2,C4orf33,SRP14-AS1,MAP4K4,CNN3,CNTN1,AHCTF1,ZFP28,CREM,CRHBP,CSF1R,PDE4DIP,FAM169A,PHF14,CTH,DCAF4,USP6NL,CCDC144A,HDAC9,ZNF337,DNAL1,SPATA2,ELMSAN1,FBXL5,TMEM130,DDX46,ALKBH8,RHOBTB1,SNAP91,EXOG,GRIN3A,NR1D2,DMTF1,CASP8AP2,PDCD6IP,RCAN1,ECM2,EBF1,FCF1,SEMA3D,TMTC1,TMEM35A,USPL1,CEP85L,ETV1,SIRPB1,EXTL2,ADGRV1,ARMCX1,CLVS1,FAM198B,ZNF585B,DLC1,RACK1,CEP78,FDFT1,GORAB,FER,TMEM164,SUCO,MEX3B,PCYOX1,SYNCRIP,RGPD5,FLT1,EFCAB2,NBEA,SMC2,TPK1,ATP2C1,ERGIC3,KHDRBS3,CELF1,STAU2,MSANTD4,SARAF,AP4B1,DOT1L,BRSK1,ABLIM2,FYN,ZMAT1,MEGF10,GABRA3,GABRG2,GAD1,FAM120B,IQGAP2,TMEM8B,LRRC37A6P,ALDH1L1,GCNT2,GHR,PPARGC1A,TCERG1,COPS8,TNRC6A,FERMT2,GPD2,TDRKH,FUT10,GPR37,GRB10,GRIA2,ADAMTS6,GUCY1B1,MAP4K5,MAN1B1,ARHGAP36,BACH2,MIER3,ELOVL5,HMGCL,HMGCR,ZDHHC15,DHX35,ICA1,ZNF181,LRRC25,IL6ST,FAM69A,INPP5B,SLC35G1,KCND2,KCNK3,LAMP2,HECTD2,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,POC1B,MMP16,COL28A1,MYO6,ZNF862,NCAM2,NF1,CNOT4,NTRK2,CLDN11,PCDH9,PCSK5,PDPK1,PFKFB2,FAM98B,FAM218A,PCDH18,SMIM7,PURG,MAPKAP1,SDK2,ING3,RETREG2,SH3KBP1,MINDY2,PPP1R1A,PPP3CA,EPDR1,SLC26A11,PRPSAP2,MASP1,APTX,CEP97,SH3TC2,FAT4,RBBP8,ERI2,RGS12,SLC25A36,PNMA8A,ROBO1,CCDC102B,EPHA10,RPL15,ATP8B4,ADAL,RPS20,HUNK,S100B,SEMA6D,SATB1,SCN2B,PEAR1,PPM1E,SHMT2,SHC4,AMBRA1,SEC31A,PREX2,SLC2A5,EPN2,SLC6A11,SMARCD3,LIMCH1,KIF13A,DOP1A,MYCBP2,SPP1,ARHGAP26,ZBTB43,RBM26,ITPRID2,STAU1,RGL1,DIP2A,ARHGEF9,PLCB1,SYT1,ANKRD28,ANKRD12,PJA1,CAMTA1,TAF9,TAL1,FAM208A,FBXW11,TCF4,SATB2,SZT2,DOCK9,DICER1-AS1,NACC2,TK2,BHLHB9,NR2E1,TMPO,BEX4,CDK20,C9orf85,ZNF346,AMACR,STXBP4,UBE2H,UBE3A,UGT8,FLRT2,PLEKHH2,ZNF709,BCL2L13,TBC1D15,ZNF781,GUSBP1,ZNF24,MICU3,ZNF45,MKRN3,LYPD6,TMEM237,ZNF189,DPYSL5,ZFAND5,GDPD5,GAL3ST3,FZD3,UBE3B,HNRNPA3,FAM219B,MSRB3,CPNE4,SPATA13" MicroRNA hsa-miR-3118:mirSVR_lowEffct hsa-miR-3118:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-109 6.72E-106 3.71E-108 3.42E-107 283 1625 "ASIC1,ABHD6,KLHL32,RNF157,ADD1,ADORA2A,KIAA1211,OLMALINC,MTA3,ZNF608,TXNDC16,ZNF578,ALCAM,PCDH10,BBOX1,AMPD2,DPP10,MAP4K3,MYH7B,KCNAB2,BCAS1,SHROOM2,CASK,LINC00173,SLC4A4,STX16,TTLL9,ADAM15,SEC11C,RGS11,BTK,SCAPER,CFAP410,CACNB4,CALM1,SPAG9,ENTPD6,SEPT7,CDH2,LRRFIP1,DLGAP1,FOXN3,B4GALT6,FBXO7,ABCG2,SRP14-AS1,CNR1,AKAP6,COL4A5,SLC4A8,COX4I1,NECTIN3,ZNF385A,CSF1R,CSNK1E,CSNK1G3,VCAN,SOCS5,FAM169A,PPP1R16B,ARHGEF4,GPSM1,RUBCN,KIAA0408,ARHGAP32,INTS1,SCRN1,ELMO1,TIAM2,MFAP3L,CHRDL1,DLX1,GRIN3A,DNM1,SLC29A4,CDON,CPEB2,DTNA,ABCC5,KRBA2,EDN3,ANKRD46,RASGRP1,PHF20L1,EGR3,PLEKHA1,PAN3,ZNF549,MRPL10,FAM198B,CEP78,ZNF589,FGF1,FLT1,SLC37A3,NELFCD,NBEA,TMEM107,HVCN1,UFM1,CAMKK2,CELF1,STAU2,AP4B1,OGA,MEGF10,ZNF559,SRRM4,GATM,GCNT2,NFU1,TTBK1,RNPS1,HPGDS,ZNF782,GNG4,GPD1,GPD2,FUT10,GPER1,ATP2B1-AS1,GRIA2,FAM19A2,KAT7,RASSF8,PADI2,BACH2,ACOT7,GABARAPL2,HMGCL,NEGR1,IDH3A,KNDC1,TJAP1,IL6ST,FAM69A,CREG2,LIMS1,PAXBP1,CHIC1,MEIS2,MGAT3,PPM1L,MKLN1,MYCN,MYO6,ZC3H12B,NF1,NPR2,NUCB2,TBC1D25,OCRL,DPY19L2P2,PCSK1,PDE4B,PDE4D,PDPK1,GPSM2,PLCL1,SLC25A23,PRIMPOL,SCHIP1,ING3,RANBP3L,VPS13C,MTMR10,TMEM260,NKAIN1,TUG1,MARCH1,PID1,CEP97,SLC25A48,CCDC40,FAM66C,NWD1,ENOX1,RASGRF1,RDX,ZMAT4,REV3L,GTDC1,RFX2,UBR7,RGS4,ALG9,ROBO1,KIRREL1,EPHA10,ARMH4,FBXW7,SPIN3,ZC3H14,ZNF671,GLDN,MAP6D1,NCBP3,ZNF331,FNIP1,CASC3,MRAS,SUPT20H,PPM1E,CPEB3,WDR37,CCDC88A,SLC12A4,CPEB4,MAST1,MYH15,FAIM2,FAM126B,DOP1A,PDZD2,FNBP1,DOK5,UHRF1BP1L,KDM4C,LHPP,ATP10B,TROVE2,SSTR1,NKAIN2,ZSCAN29,ARHGEF9,SYN2,COBL,MTCL1,PJA1,CAMTA1,ADGRL3,SIN3B,RPGRIP1L,SZT2,SYNE1,PHF24,PCDHB7,PUM2,TNS2,FRYL,CCDC173,PMS2CL,AP4E1,ZNF106,MTMR14,FAM124A,ELP5,TRIO,TRO,STXBP4,TRPS1,DCBLD1,TTTY15,UBTF,GORASP1,PLEKHH2,CCDC136,VLDLR,TBC1D15,KLC2,CLDND1,KCNK12,ZNF45,LYPD6,TMEM237,POLR3H,EML6,SMARCAD1,UPF3A,ZXDA,CADM2,SLC38A1,RNF103,FIP1L1,EPM2A,DOCK8,ST7,HNRNPA3,JMJD1C,RNF170,SNX14,FAM181A,GAN" MicroRNA hsa-miR-93:mirSVR_highEffct hsa-miR-93:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.31E-109 7.30E-106 4.01E-108 3.69E-107 282 1614 "KCNH8,NCKAP5,SLC24A4,KIAA1324,ABCD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,LINC00173,STK33,RASL11B,SLC4A4,ATP1B3,ATP2A2,DPY19L3,ADGRB3,NRP2,MTMR3,JAZF1,CALB2,PRC1,CBR1,USP6,C1orf52,TIGD7,CFL2,MS4A7,TAOK2,EPS15L1,ABCG2,C4orf33,ARMC8,AKAP5,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,GREB1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,FAM78B,DNAJB6,DNM1L,E2F5,EDN3,ANKRD46,FAM13A,SUGP2,KMT5B,EGR3,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,F8,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,FGFR1,SUCO,SEMA4D,FLT1,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,ZMAT1,GABBR1,B4GALNT1,ERAP1,SYT17,DISC1,ADAM28,RAB30,TNRC6A,KDM2B,DCLK2,RAB40B,TDRKH,GPR37,DIDO1,CIT,AP4S1,IRAK3,HAS2,MIER3,MSL1,METTL21A,KCNJ16,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,NCOA7,SMAD1,MAN2A2,MAP6,MAT2A,AQP11,LRP1B,SRSF12,KITLG,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,RETREG2,EPB41L4B,DRAM2,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,PTPN13,PTPRD,CEP97,USP47,FAT4,ZNF493,OXR1,RASGRF2,REV3L,GTDC1,SLC25A36,PBRM1,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,ZC3H13,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,NKAIN2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,FAM189A1,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,CELF4,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,DPF3" MicroRNA hsa-miR-26a:mirSVR_lowEffct hsa-miR-26a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-109 7.77E-106 4.23E-108 3.89E-107 307 1911 "KCNH8,KLHL32,AXIN2,RNF150,ADRB2,DPY19L2P4,MTUS1,KCTD16,KIAA1324,SPARCL1,ABCD2,ARHGAP20,PCDH10,FAM135A,SYT13,AMPH,AMT,OGT,ANK2,PKP4,EPB41L5,USP37,LGR5,PPP4R4,CASK,NUMB,MYOM1,DOCK11,SEC11C,NRP2,CACNA1G,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,SLIT2,RAB28,PPT2,C4orf33,CNTFR,AKAP6,COL9A1,LETMD1,AKAP5,SLC4A8,AHCTF1,CPS1,PREPL,CREM,AKAP12,ANKRD44,SUSD5,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,GPSM1,CCDC144A,CYBB,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,LIN54,MATR3,DGKB,PABPC5,DBI,DNAL1,ARMCX4,ARMCX2,YTHDC1,ZBTB24,ELMO1,KIAA0753,KLHL3,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RAB39B,DYNC1I1,CPEB2,DOCK2,DRP2,ECM2,MAMLD1,GOLT1B,E2F5,AASDH,EDIL3,EDN3,EDNRB,CNNM1,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,C8orf37,DCTN4,USPL1,ENPP6,CDKL3,EYA1,F5,F8,FAM198B,ACSL4,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,POLK,UBE2E3,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,ZMAT1,GABRB3,GABRG1,FAM120B,IQGAP2,GATM,IGSF5,MSTN,NFU1,MALT1,SPIN1,GLI2,FERMT2,GPR12,GPR37,TMEM121B,PCLO,PLCD4,ATE1,ZBTB45,PSIP1,GUCY1A1,RASSF8,DDX19B,ARHGAP36,ELOVL5,HNMT,SMAP1,IGF1,SCIN,IL12A,ZNF678,INPP5B,SLC35G1,METTL21A,KCNB1,IPO5,CYP27C1,STMN1,HECTD2,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,SAMD5,MSI1,MT1M,LAYN,NCAM2,NEFH,NOVA1,SMIM11A,CNTN3,PCDHGC3,PCSK5,PDE4B,PFKFB2,FAM216A,SCHIP1,SH3KBP1,CCDC144B,PPP2R2B,LRRN3,PPP2R5E,RASGEF1B,PRKACB,RELN,CNTLN,PTCH1,ANKHD1,BDNF-AS,PTK2,TMEM260,PTPRB,EML5,PTPRE,PTPRH,PEX2,ZSCAN2,TUG1,PID1,ACSS3,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,RET,REV3L,GTDC1,LGI2,CCDC82,EXD2,C12orf49,ALG9,SNX22,RPS6KA2,KCNIP3,RYR3,ATXN2,TNFRSF19,SUPT20H,FERMT1,FNDC3A,CNKSR2,NUBPL,PPP4R3A,SLC6A8,SLC12A2,SNRPN,FAM126B,TRERF1,BDP1,KDM4C,ERC1,PEG10,RBM26,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,ADAMTS17,SYN1,COBL,CAMTA1,ALG1,DMXL2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,GPRIN3,SIRT1,ZFPM2,ITGB3BP,ZNF106,AKTIP,SLC44A1,TLR4,NPL,RGMB,SYNPO2,TRIO,CLHC1,FLRT2,USP1,WIPF1,XPO1,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,URM1,KCNAB1,DOCK8,PHTF2,FBXO36,ACTR3B,NETO1,CPNE4" MicroRNA hsa-miR-20a:mirSVR_highEffct hsa-miR-20a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.39E-109 7.78E-106 4.23E-108 3.89E-107 288 1684 "KCNH8,NCKAP5,SLC24A4,HACE1,ABCD2,ARHGAP20,SEMA7A,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,CASK,LINC00173,STK33,RASL11B,SLC4A4,EIF4G3,ATP1B3,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,USP6,P2RX6,C1orf52,TIGD7,CFL2,MS4A7,B4GALT6,TAOK2,EPS15L1,ABCG2,C4orf33,AKAP5,SLC4A8,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,ZBTB24,MYEF2,MFAP3L,FBXL5,SACS,USP3,CPEB2,DMTF1,DPYSL2,DTNA,DNAJB6,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,EFCAB2,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,FYB1,GABBR1,TRAF3IP2,B4GALNT1,ERAP1,SYT17,DISC1,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,ATP2B1-AS1,DIDO1,CIT,AP4S1,RABL2A,IRAK3,HAS2,MSL1,METTL21A,KCNJ16,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,SRSF12,KITLG,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NCF2,SFR1,NELL2,NF1,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,ETFRF1,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,TMEM260,PTPN13,PTPRD,PTPRO,CEP97,TMEM255A,USP47,FAT4,OXR1,RASGRF2,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,ATXN2,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,NKAIN2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,FAM189A1,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,CELF4,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,RNF103,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-198:mirSVR_lowEffct hsa-miR-198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-109 8.23E-106 4.45E-108 4.10E-107 294 1755 "EMILIN3,SYS1,NDRG3,GALNT16,AP2A2,KLHL13,PCDH19,TBC1D14,AK2,SYT13,TRMT9B,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,APBA2,APBB2,EPB41L5,PPFIA3,USP37,CPNE5,LGR5,SFMBT2,SEMA4G,LINC00173,ZBTB10,NCOA1,TMEM108,ATP1A1,ATP2B2,RNF182,RIPK1,LINC00847,KSR1,GYG2,MYRF,CA12,THSD7A,CAMK2G,CH25H,RUNX1T1,MTMR7,LOC730101,NUMBL,CFL2,SRSF11,CHN2,EPS15L1,CPNE6,STOML1,SULT4A1,SRP14-AS1,CNR1,COL4A5,ABI3BP,TBPL1,COX4I1,BAG4,ZFP28,AKAP12,NCOR2,GDA,TRIM69,ABCG1,CS,CSF1,SEC24C,VAC14-AS1,ERC2,ARHGEF4,BOC,DOCK4,HDAC9,ARHGAP32,GAPVD1,TCAF1,ZFYVE16,EARS2,ZBTB24,HEPH,ELMO1,MFAP3L,KIAA0319,POM121,SACS,CHRDL1,EXOG,GRIN3A,DMD,DPP6,PDCD6IP,ARRDC4,DUSP9,DNAJB6,AASDH,HIPK3,HEYL,FAM13A,PHF20L1,SUGP2,CERCAM,EMX2,EPB41L2,EPHB1,SPEG,ETV1,SIRPB1,KATNAL1,MRVI1,RPS6KC1,PTK2B,CEP78,CHST15,FDFT1,KAT8,ZNF589,GTF2IRD2,AMOTL2,HPCAL4,SLC37A3,HVCN1,CAMKK2,ATP6V1H,ZMAT1,GAD1,IQGAP2,DISC1,NEU3,TUBGCP4,ADAM28,GFRA2,GGT5,TCERG1,COPS8,GLYR1,STARD3,GNG4,CCDC184,SPACA9,ADAMTS13,BTN2A1,RNF165,COQ10A,RABL2A,LINGO1,TOX2,MAN1B1,ATXN2L,TNFAIP8L3,GABARAPL2,SYNPO,SHISA6,CELF5,METTL21A,KCND1,KCNH2,KIF2A,MAN2A2,MATN2,CHIC1,MEIS1,AFDN,SAMD5,COMMD5,ADAM22,LYRM9,MYO7A,ZC3H12B,NF1,NFYA,NOVA1,DNHD1,SMIM11A,NUCB2,SETD4,OGG1,OXTR,PFKFB3,NLGN3,PIK3C2A,PDZRN4,POU6F1,PPP2R5E,PPP3CA,KANSL1,PRKAB2,PKIA,GDPD1,PSD,WDR25,PTCH1,BDNF-AS,MTMR10,ELOVL2,PTPRB,PTPRG,PEX2,TTC13,STRC,MARCH1,TMEM255A,FAM66C,SUSD4,NWD1,PRRT2,RFX2,UBR7,RGS3,TMLHE,ROBO1,KIRREL1,PCMTD2,SNX22,NEK11,FBXW7,ZC3H14,SGSM1,MEG3,ATAT1,RTN1,LRFN5,PEAR1,ZNF821,GALNT10,STUM,PPM1E,ASAP3,MYO18A,HKDC1,ST6GAL1,NLGN1,SLA,EPN2,PKNOX2,SLC8A1,ELMO2,BTBD7,ATF7IP,SMARCD3,INTS9,DOP1A,SPP1,UNC5B,RBM26,POGZ,SS18,STAC2,PHLDB1,ARHGEF9,NUDT10,ARC,SLC37A2,TBCEL,KLHL4,WSCD1,DOCK9,PMS2CL,DICER1-AS1,AP4E1,GALNT17,ARL10,ENHO,TMPO,R3HDM1,PIK3R5,TPM1,TPM2,SMUG1,STXBP4,PPIL6,ZKSCAN5,RBFOX3,WIPF1,WNT7A,LGI4,SLC47A2,ELFN1,ZNF177,POLR3H,EML6,CADM2,NAV3,FIP1L1,PDSS2,FZD3,UBE3B,KAT6A,SMIM8,PHTF2,CASC15,ACTR3B,RSPRY1,ZDHHC20,SOCS4,FAM198A" MicroRNA hsa-miR-943:mirSVR_lowEffct hsa-miR-943:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-109 8.93E-106 4.80E-108 4.42E-107 260 1369 "KCNH8,CLK4,RNF150,BEND6,ZNF608,AK2,ARHGAP20,PCDH10,GPRASP2,AMPH,ANK2,MYH7B,FAM131A,BCAS1,USP37,SHROOM2,ARNTL,MARK4,SLC4A4,RNF182,ADAM15,BBS2,BCHE,BID,BMPR1B,C5,WASF1,CALM1,KALRN,CAMK2G,CAST,METTL6,SLC16A4,ARHGEF1,CBFA2T2,LRRFIP1,EVI5L,NOG,NDST3,ARHGAP22,QKI,MAP4K4,ARMC8,NECTIN3,ANKRD44,CSF1R,RGS6,ARHGEF10,OSBPL3,CSNK1G3,SLITRK5,KIAA0040,ARHGEF4,RIMS2,KIAA0408,DOCK4,ARHGAP32,SNPH,ARHGAP24,DCAF8,DGKB,KIAA0319,PARD6A,CHRDL1,EXOG,DMD,SLC29A4,CPEB2,PDCD6IP,DTNB,DUSP9,ABCC5,DNM1L,KRBA2,E2F6,AASDH,EDN1,HIPK3,RASGRP1,SEMA3D,MBNL2,KMT5B,AASS,LRRC17,ETV1,F5,SCML2,ZNF589,FER,SUCO,ATP13A4,ANKFY1,NBEA,SMC2,HVCN1,ATP6V1H,AP4B1,CHL1,GCNT2,TUBGCP4,PPARGC1A,LYVE1,RAB30,TOX3,LUZP2,GNAL,ZNF782,ADGRA3,GPD1,GPD2,TDRKH,FAM19A2,BVES,FAM107A,IRAK3,HLF,GABARAPL2,HMGCL,AGBL5,HNMT,ZDHHC15,IRF8,MSL1,C2orf72,ZIC5,IL6ST,INPP5B,SLC35G1,KCND1,STXBP5,PIK3AP1,ZNF667-AS1,MBNL1,MBP,MEIS1,POC1B,MMP16,BLOC1S2,MYCN,NPTX1,NTRK2,OPA1,P2RY1,PDE4B,PFKFB4,PIK3C2A,PLTP,PPARA,MINDY2,PPP1R1A,CCDC144B,PRKACB,PRKCB,HYDIN,CNTLN,ANKHD1,PTPRB,TUG1,TMEM231,FAM66C,SH3TC2,MSANTD2,REV3L,RGS3,RNASEL,ALG9,ROBO2,ELP2,PCMTD2,MRAP2,ZC3H14,MCMBP,GLDN,ST6GALNAC6,RYR3,ZNF331,ATXN2,PRCD,GALNT10,TRA2B,KIF21A,PPM1E,AMBRA1,FBXO11,CCDC92,DZIP1,ANKRD6,SLA,KANSL3,SLC14A1,SMARCA4,MAST1,SMARCD3,ANKRD36,MBD5,FAM219A,BDP1,FNBP1,ZSWIM8,SP4,UHRF1BP1L,KDM4C,SPART,CLASP2,CLSTN2,NKAIN2,SS18,KANK1,SULF2,SYN2,PJA1,ADGRL3,DMXL2,TPCN2,DOCK9,PCDHB7,TNS2,GPRIN3,PMS2CL,ZFPM2,AP4E1,ARL10,TIAM1,MTMR14,TMEM9,TLR4,KAT6B,TRIO,RUNDC3B,AMACR,TRPM2,PPIL6,TSN,SSBP2,TTTY15,PLEKHH2,BCL2L13,VLDLR,WIPF1,CLDND1,RICTOR,ZNF24,ZNF28,TRIM9,ZNF45,SPHK2,POLR3H,AMZ1,ZFAND5,CADM2,NAV3,PLSCR4,ST7,UBE3B,FBXO36,JMJD1C,TRAM2-AS1,RNF170,FRMD6,AP3B2" MicroRNA hsa-miR-520g:mirSVR_highEffct hsa-miR-520g:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-109 1.86E-105 9.97E-108 9.18E-107 262 1395 "RALGAPA1,SYN3,KLHL32,ESYT2,BEND6,SLC24A4,ZNF608,INTS2,RTL9,KIAA1324,WDR35,ALCAM,GPRASP2,PARG,APC,CDK13,STK33,EIF4G3,ATP2A2,ADGRB2,ADGRB3,MPDZ,FUBP1,JAZF1,SGCE,CALB2,SLC25A14,CAST,HIP1R,CBFA2T2,DGKI,MAGI1,CCPG1,CLGN,B4GALT6,LHX2,RAB28,ABCG2,CNR1,AKAP7,ARMC8,FAM149A,AHCTF1,CDC42BPB,CREM,ENTPD4,ANKRD44,GDA,LRRC3B,CSNK1E,OSBPL3,SLITRK5,RUBCN,GPRASP1,RIPOR2,DBN1,HEPH,TIAM2,DDX46,RHOBTB1,SNAP91,RAB39B,DMD,USP3,DMTF1,DNAJB6,DNM1L,EDNRA,FCF1,RASGRP1,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,IRAK4,COPS4,PLEKHA1,C8orf37,PAN3,DCTN4,TUBD1,EPB41L2,EYA1,CLVS1,ACSL4,SCML2,CEP78,FDFT1,GTF2IRD2,FGF12,FOXF2,RGPD5,IQCG,ANKFY1,C2orf88,EFCAB2,JKAMP,TRMO,NBEA,ATP6V1H,KHDRBS3,MSANTD4,MPP6,OGA,HRASLS5,INPP5K,TCERG1,COPS8,TOX3,TNRC6A,ZNF638,DCLK2,FUT10,DIDO1,GRIN2C,ZNF496,CIT,GSTT2,LINGO1,HAS2,MAN1B1,MSL1,ZNF678,METTL21A,KCNN2,IPO5,TTYH2,LIMS1,HECTD2,ZFYVE27,MAP6,MAT2A,MBNL1,MEIS1,SRSF12,MEST,MID1,MXI1,MYCN,RTL5,NCAM2,SLC11A2,SETD4,OCRL,OGG1,LOC100128398,GPR137C,CNTN3,PCDH8,PRTG,PDE4A,PDE4D,FAM98B,FAM216A,PPP2R5E,PPP3CA,KANSL1,PKIA,HYDIN,WBP1L,CNTLN,PTK2,PTN,TMEM260,PTPN13,EML5,PTPRO,ZNF793,RBBP6,MSANTD2,RFX3,RGS3,RNASEL,CARF,ROBO1,ELP2,FBXW7,ATAT1,KCNIP1,RTN1,RYR3,DGLUCY,SALL1,ATXN7,LRFN5,SCP2,TNFRSF19,HSPA4L,SH3GL3,FERMT1,CPEB3,CHD9,FBXO11,FHOD3,NLGN1,SLA,BTBD3,DHX30,SEPHS1,ARHGEF40,GKAP1,DMRTC1,CDK5RAP2,ZNF415,FAM126B,SPP1,ERC1,ZBTB43,CLASP2,ITPRID2,MESP1,SAMSN1,ZC4H2,SS18,ELOVL4,SEPT8,ARHGEF9,PLCB1,SYT1,FBXW11,TCF4,SATB2,TCF12,SYNE1,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,ZFPM2,AP4E1,THRA,HEY1,BHLHB9,TMPO,RIMBP2,TPM1,PDSS1,AMACR,ZKSCAN5,GORASP1,PLEKHH2,VLDLR,TBC1D15,LAT2,CLDND1,SLC47A2,ZNF74,FIP1L1,FAM47E,RTN4,PHTF2,ADAMTSL3,JMJD1C,FRMD6,DPF3" MicroRNA hsa-miR-3171:mirSVR_lowEffct hsa-miR-3171:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.78E-109 2.68E-105 1.42E-107 1.31E-106 303 1871 "KDM5D,KIAA1211,PTCHD1,ZNF608,KCTD16,OSBPL1A,NME5,OSBPL6,WDR35,TAOK1,ALCAM,LRCH2,C6orf89,CCDC146,MAP4K3,APAF1,MAGEE2,NT5C3B,VAT1L,BCAS1,LGR5,IGDCC4,CDK13,ASPA,NUMB,ATP1A1,EIF4G3,ZNF582,N4BP2L1,DOCK11,BBS2,FUBP1,SCAPER,SGCE,WASF1,CACNB4,PTBP2,VXN,ISPD,CBLN1,MTMR7,LRRFIP1,SRSF11,MS4A7,NRXN3,QKI,ARHGEF6,CNR1,ARMC8,AKAP6,COL4A5,COL9A1,SLC4A8,AHCTF1,ZNF521,FAM171B,CRHBP,GDA,SEC24C,PLXNA4,KIAA0040,ZSCAN23,FAM131B,CCDC144A,ARHGAP32,GAPVD1,ARHGAP24,ZFYVE16,EARS2,KIAA0586,TMEM170A,DAPK1,DBI,GIT2,SPATA2,YTHDC1,JAKMIP2,MYEF2,ELMO1,MTX3,WDR20,DNAH9,GOLT1B,WDPCP,EDNRA,EDNRB,HIPK3,FCF1,SEMA3D,TMTC1,FRY,FAM13A,MBNL2,VPS13B,EPB41L2,COQ7,LRRC17,ENPP6,GPHN,DENND4A,NCALD,ZNF549,KATNAL1,EYA1,EZH1,CLVS1,ABCA8,TAOK3,SUCO,MEX3B,SYNCRIP,RGPD5,SLC37A3,TRMO,ATP2C1,PRELID3A,CELF1,SARAF,ZNF559,DISC1,GCNT2,CYP46A1,ADAM28,PCDH17,PPARGC1A,DBF4,KDM2B,LUZP2,LNX1,GPR34,PCLO,DIDO1,BTN2A1,PADI2,FRMD3,ELOVL5,TCEAL6,IGF1,LRRCC1,SCIN,ZNF678,INSM1,SLC35G1,KIF5A,KIT,LMO2,PACRG,SMAD1,GPR155,MAP2,MARK1,LYPLAL1,MBD1,MEF2C,MGAT3,MYO5A,MYO9A,HNRNPM,SFR1,NEFH,CNOT4,DNHD1,NPTX2,NRCAM,NUCB2,OPA1,ZNF713,OXTR,PCDH9,PRTG,PDE3A,GPR85,GNG2,ZDHHC8,ZNF655,SNX10,PLCL1,PCDH18,MTRF1L,PMP22,TRHDE,STRN3,LRP12,PSAT1,PPM1B,PPP2R2C,LRRN3,PPP2R5E,PRKACB,DIRAS2,GDPD1,ANKHD1,SPDL1,PTPRB,PTPRG,TUG1,RAD51D,FAM66C,ZNF793,OXR1,MSANTD2,RGS4,RIC8B,ZFHX4,EXD2,RPE,NEK11,RPL15,ATP8B4,LRRK2,RXRA,TRAPPC13,SAFB,SALL1,SATB1,FOXRED1,SUPT20H,ZFP30,PPM1E,CHD9,FNDC3A,FHOD3,NLGN1,PPP4R3A,BTBD3,SLC8A1,SLC12A2,MTERF2,SLC22A4,TET1,CPEB4,RCOR3,SNRPN,DOP1A,PDZD2,UHRF1BP1L,KDM4C,ZNF423,TSPYL2,RBM26,ITPRID2,LARP4,NKAIN2,DIP2A,NECAB1,PRRC2C,VPS13A,ADAMTS17,ADGRL3,KIAA1107,IQCE,DMXL2,SATB2,ZEB1,TRIM2,RPGRIP1L,TCF12,CLASP1,PCDHB10,ARHGAP9,DICER1,ZFPM2,ITGB3BP,TIAM1,ACTR6,TLR4,PRRT1,R3HDM1,TP53BP2,ZNF346,TRIO,PPIL6,SGK3,EIF4ENIF1,USP1,WIPF1,P2RY12,CLDND1,XRCC4,PCDH20,NDRG4,ZBTB38,FSTL5,TMEM198,FTSJ1,DHX33,CADM2,SLC38A1,RNF103,MDH1B,NAV3,DNAH10,FAM13C,FZD3,JMJD1C,RNF170,TTC7A,NHSL1,SNX14,NETO1,SOCS4,ST8SIA2,SENP7" MicroRNA hsa-miR-323b-3p:mirSVR_lowEffct hsa-miR-323b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.48E-109 3.63E-105 1.92E-107 1.77E-106 272 1510 "RALGAPA1,SYN3,NCKAP5,TMCC3,PTCHD1,ADRA1D,INTS2,PCDH19,CC2D2A,AK2,SMIM17,SYT13,AMPD2,DPP10,EP400,MAGEE2,ZFYVE28,PDE8B,STK33,CHRD,CCAR2,ATP6V1G2,ADAM23,ST3GAL5,CALM1,PTBP2,SLC25A14,CAST,ISPD,ARHGEF25,CBR1,SLC16A4,CD38,LRBA,SEPT7,CDH2,ZMYM4,ZNF445,CDO1,DLGAP1,TIGD7,CCPG1,CLGN,C7orf61,RAB28,MAP4K4,CNN3,AKAP7,LETMD1,ZNF521,SEC31B,TRIM69,CS,SNCAIP,SEC24C,ARHGEF10,CSNK1E,SOCS5,SLITRK5,APPL1,KIAA0408,TMEM170A,SPOCK2,DBI,PITPNC1,RUSC2,TMEM130,ZC3H11A,DDX46,PLPPR4,SNAP91,SACS,WDR20,EXOG,DNM1,NR1D2,CASP8AP2,AASDH,EBF1,EDN1,HIPK3,PHF20L1,SUGP2,EGFR,KMT5B,RABEPK,SH3YL1,DLC1,FCGRT,MED12L,FGF1,FGF14,PRKAG2,FLT1,FOLH1,JKAMP,UFM1,NSG1,STAU2,GALNT15,GABRG1,ZNF274,ERAP1,MTHFD2,IGSF5,SULT1C4,WASHC2A,ADAM28,MMADHC,DBF4,TNRC6A,GLUL,HTATSF1,MAP7D2,DCLK2,GRIA2,GRM8,PSIP1,MAP4K5,ATOH8,NXPH3,HLF,GABARAPL2,AGFG1,ICA1,IDH3A,IFI16,RBPJ,IL6ST,IL12A,LIG4,HECTD2,MEIS1,MEST,KITLG,MSI1,NRBP2,MXI1,NCAM2,NEFM,NF1,ALDH1L2,DNHD1,NTRK3,CLDN11,PDE4B,PDE4D,PFKFB2,ABCB1,KCTD15,NLE1,FAM216A,PLCL1,PURG,TRHDE,STRN3,LRP12,EPB41L4B,PPM1B,CCDC144B,KANSL1,PKIA,MAPK4,HYDIN,GDPD1,RELN,VPS13C,WBP1L,QRICH1,CNTLN,PTCH1,BDNF-AS,PTPN13,PTPRD,EML5,C1orf109,ZNF615,QDPR,CCDC40,ZNF793,FAM184A,NWD1,OXR1,KHDRBS2,MSANTD2,RDX,FIGN,RFX3,RGS12,KCTD17,SLC25A36,RNASEL,ZFHX4,C12orf49,ROBO1,ROBO2,ELP2,CCDC102B,BAALC,RMI1,SMPD3,TRA2B,HSPA4L,SGK1,PPM1E,KIF16B,CNKSR2,SYBU,SLC6A11,CCDC88A,SLC9A5,TRIM67,ELMO2,TTC17,ANKRD36,MBD5,TMCC1,MYO16,RBM34,FNBP1,DOK5,MYCBP2,MCF2L2,LMO3,LARP4,NXT2,SYNE2,COBL,ANKRD28,ZEB1,TRIM2,SYNE1,PCDHB6,SIK3,TEK,ZFPM2,ZMAT3,KAT6B,TPM1,C9orf85,RGMB,TSC1,FAM155A,UGT8,BCL2L13,MGAT5B,CCDC14,WIPF1,RICTOR,XRCC4,ZBTB14,ZIC2,ZNF28,ZNF540,CELF4,ZBTB38,SPIRE1,EVI5,STOX2,HPS4,NAV3,FAM47E,PDSS2,RGS7BP,FZD3,RTN4,ACTR3B,SNX14,KLHDC1,DPF3,GAN,CPNE4" MicroRNA hsa-miR-625*:mirSVR_lowEffct hsa-miR-625*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.78E-109 4.35E-105 2.29E-107 2.11E-106 260 1378 "KCNH8,FMNL2,CCDC85A,TMCC3,PLEKHH1,PTCHD1,ADRB2,BEND6,ZNF608,CASKIN1,OSBPL1A,CC2D2A,C1QTNF3,MARCH4,PCDH10,FAM135A,OGT,DPP10,LCORL,MAP4K3,SMIM29,SUGT1P4-STRA6LP-CCDC180,PARG,LINC00173,STK33,ASPA,ZBTB10,BACH1,DST,BTK,MYRF,PTBP2,VXN,CH25H,RUNX1T1,LDB2,MTMR7,CD38,DCLK1,ZNF445,TIGD7,NOG,UBE2L6,SRSF11,SOCS6,CHN1,NDST3,LHX2,CLCN3,CLTC,C4orf33,CNN3,CNR1,IQCK,ARMC8,COL4A5,BAG4,RBM39,SNCAIP,VCAN,FAM169A,KIAA0040,UBXN2A,PUM1,CCDC144A,DOCK4,ARHGAP32,LONRF1,LIN54,TMEM170A,TIAM2,KIAA0319,ALKBH8,RHOBTB1,SPOCK3,WDR20,CDON,DRP2,PDCD6IP,DTNA,DNAJB6,EBF1,TMTC1,PHF20L1,KMT5B,EGR3,GOLGA7,ASB3,PCOLCE2,VPS13B,GPHN,ZNF549,MRVI1,DLC1,SEC24B,FER,POLR1B,FGFR3,POLK,UBE2E3,IQCG,UFM1,PDLIM5,ATP6V1H,KHDRBS3,TVP23A,ZMAT1,CHL1,RAPGEF6,MTHFD2,GATM,GHR,PPARGC1A,GPR75,TOX3,CBX1,KDM2B,LUZP2,DCLK2,RAB40B,PCLO,ZBTB49,RABL2A,LINGO1,RASSF8,ZHX1,MAN1B1,FRMD3,ELOVL5,HNF4G,ZDHHC15,ZIC5,RBPJ,ZNF678,SLC35G1,IPO5,LAMP2,LIG4,HECTD2,PIK3AP1,MARK3,AQP11,MBNL1,LRP1B,MEIS2,SRSF12,MIA2,MID1,MITF,ADAM22,MYO5A,MYO9A,ZC3H12B,CNOT4,NTRK2,NUCB2,DPY19L2P2,PDE3A,PDE4B,SLC10A4,PFKFB2,GPSM2,PCDH18,PDZRN4,STRN3,SH3KBP1,PPP2R5E,PPP3CA,KANSL1,SNRK,CNTLN,ANKHD1,TMEM260,PTPRG,USP47,FAM184A,NWD1,ZCWPW1,RASGRF2,RBBP8,RADX,ZMAT4,ZFHX4,TMLHE,CCDC102B,RPL15,FBXW7,ATXN7,FNIP1,GALNT10,MRAS,KIF16B,CPEB3,SHC4,FNDC3A,SYBU,NLGN1,NUBPL,PPP4R3A,SLC8A1,ARHGEF40,ELMO2,BTBD7,TET1,GKAP1,ANKRD36,MBD5,SNRPN,USP33,DOP1A,BDP1,SOX11,SPP1,SPART,NKAIN2,ERBIN,NECAB1,ARHGEF9,TAF9,ADGRL3,KLHL4,TRIM2,SYNE1,DOCK9,PCDHB10,PCDHA5,ZFPM2,TIAM1,R3HDM1,TP53BP1,TPM1,NPL,SYNPO2,STXBP4,SGK3,OSBP2,CCDC14,PCDH20,ZIC1,ZNF711,KCNT2,ZNF154,FSTL5,FTSJ1,DHX33,SLC30A4,STOX2,PRDM8,PRDM10,FIP1L1,PDSS2,FAM13C,RTN4,PHTF2,FBXO36,ADAMTSL3,JMJD1C,KLHDC1,FXR1,CPNE4" MicroRNA hsa-miR-1915:mirSVR_lowEffct hsa-miR-1915:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.65E-109 5.40E-105 2.83E-107 2.60E-106 291 1732 "ABR,SYS1,NDRG2,TMEM132B,GALNT16,ADRA1B,MTA3,OSBPL1A,SORCS2,AMPD2,EP400,MYH7B,PPFIA4,APBB2,APLP1,BCAS1,AQP6,MADD,SPTBN4,ARHGDIG,ARNTL,PLA2G4C,CCDC74A,ZSCAN18,PCDHGB4,ATP1A3,SLC2A11,N4BP2L1,ADAM15,SEC11C,RGS9,ST3GAL5,SYNJ2,CACNA1I,MYRF,CA4,KALRN,PTBP2,CAMK2A,PRC1,SCARB1,ARHGEF2,CDC25B,ZBED1,TBRG4,PLEKHB1,TAOK2,EPS15L1,CPNE6,RAB28,PPT2,ABCG2,TMEM184B,IGLON5,ARMC8,SLC4A8,SMARCAL1,ZNF521,SLC35F1,SNCAIP,SUSD5,IPCEF1,RIMS4,CST3,PUM1,ARHGAP32,DAPK3,DBN1,ELMSAN1,DGCR5,TIAM2,LYPD1,DMPK,RPS6KL1,DPH1,CASP8AP2,DTNA,DNM1L,PHC2,FRY,APH1A,EIF4G1,EIF4G2,ELN,ZNF549,MRVI1,NRN1,F5,ACSL4,TUBB3,CORO2B,ZNF589,FGF12,HPCAL4,IP6K2,FOXO3,FLNC,NOP56,SYT3,SPECC1,ERGIC3,KHDRBS3,CELF1,CGREF1,GABBR1,TRAF3IP2,FAM120B,B4GALNT1,TMEM8B,ACSS1,KIAA1841,GCK,TUBA8,SRCAP,ADAM28,GGT7,TOX3,STARD3,GPD1,TDRKH,CCDC184,GRIN2C,PRDM5,LINC01089,KAT7,FAM107A,ADAMTS6,SLC2A6,BACH2,SYNPO,HMGCL,TCEAL6,IDH3A,C2orf72,IGF1,SLC35G1,METTL21A,KCNH2,KCNJ5,KCNN1,KCNN2,LINC00634,A1BG-AS1,CYP27C1,CAMK2N2,LSS,PACRG,CLEC18A,MAN2A2,MAP4,SRSF12,SCAMP5,PTOV1,MXI1,MYCN,MYT1,NEFM,NPTX2,OGG1,PCDHGC3,PDE4D,PDE1B,GNG2,PFKFB3,DUSP26,NLGN3,ZNF655,ZFYVE21,PLCD1,ANKRD16,SCHIP1,SEPT4,POU6F1,PRKCB,MAPK10,DIRAS2,MASP1,NDUFS7,SNRK,PIGG,CNTLN,NCR3LG1,RIPOR1,NKAIN1,TUG1,TMEM231,USP47,GTDC1,KCTD17,RNASEL,RNH1,DCUN1D2,EXD2,C12orf49,CYB561D1,KIRREL1,EPHA10,BAALC,KIAA0895L,TCP11L1,MEG3,ATAT1,KCNIP3,DGLUCY,MAPK12,SBF1,CSRNP3,SCN2B,HES6,SHMT2,SLA,PKNOX2,SLC6A8,RADIL,ARHGEF40,SLC9A5,KBTBD4,ELMO2,INAVA,FAIM2,SNRPN,BDP1,KDM4C,SPTB,IQSEC2,STAC2,STXBP1,NSFL1C,SUPT5H,MMS19,TAL1,TBCEL,FBXW11,NEU4,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,OBSL1,TNS2,ARHGAP9,HIF3A,CYB561A3,PMS2CL,GALNT17,ARL10,MTMR14,TLR4,NR2E1,LRRC8A,NPL,IL34,ZNF346,TRPM2,RUSC1,KCNE5,TSC1,SGK3,RPRM,UBE2H,OSBP2,FLRT2,CLIP2,WNT7A,SLC47A2,PCDH20,ATP6V0E2,EML6,FTSJ1,ZNF213,MEIS3,DHX33,HPS4,SEMA3B,PCBP4,HRASLS,ZDHHC20,NETO2,SOCS4,ST8SIA2,LAS1L,PRRT4" MicroRNA hsa-miR-1297:mirSVR_lowEffct hsa-miR-1297:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-108 5.79E-105 3.01E-107 2.77E-106 295 1780 "KCNH8,KLHL32,AXIN2,RNF150,ADRB2,DPY19L2P4,MTUS1,KCTD16,SPARCL1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,AMPH,AMT,OGT,PPFIA4,PKP4,EPB41L5,USP37,LGR5,PPP4R4,MYOM1,DOCK11,SEC11C,NRP2,MTMR2,CACNA1G,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,SLIT2,RAB28,PPT2,C4orf33,CNTFR,AKAP6,COL9A1,AKAP5,SLC4A8,AHCTF1,CPS1,FAM171B,PREPL,CREM,ANKRD44,SUSD5,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,RIMS2,GPSM1,CCDC144A,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,LIN54,MATR3,DGKB,PABPC5,DNAL1,ARMCX4,ZBTB24,KIAA0753,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RAB39B,DYNC1I1,CPEB2,DOCK2,ECM2,MAMLD1,GOLT1B,AASDH,EDNRB,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,C8orf37,DCTN4,USPL1,GPHN,CDKL3,F5,F8,ACSL4,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,PRKAG2,POLK,UBE2E3,IP6K2,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,ZMAT1,GABRB3,GABRG1,FAM120B,IQGAP2,GATM,IGSF5,MSTN,NFU1,PCDH17,MALT1,TCERG1,SPIN1,GLI2,FERMT2,GPR12,GPR37,PCLO,GRIA2,ATE1,ZBTB45,PSIP1,GUCY1A1,DDX19B,ARHGAP36,ELOVL5,HNMT,HSPA1L,SMAP1,MSL1,IGF1,SCIN,IL12A,ZNF678,INPP5B,JAK2,SLC35G1,METTL21A,KCNB1,IPO5,STXBP5,KTN1,STMN1,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,SAMD5,MSI1,MT1M,LAYN,NEFH,NOVA1,SMIM11A,CNTN3,PCDHGC3,PDE4B,PDE4D,PFKFB2,PDZRN4,SCHIP1,RETREG2,SH3KBP1,CCDC144B,PPP2R2B,LRRN3,PPP2R5E,RASGEF1B,PRKACB,RELN,CNTLN,PTCH1,ANKHD1,BDNF-AS,PTK2,TMEM260,PTPRB,EML5,PTPRE,PTPRH,ZSCAN2,TUG1,PID1,ACSS3,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,REV3L,ERI2,GTDC1,RNASEL,LGI2,CCDC82,EXD2,C12orf49,ALG9,SNX22,RPS6KA2,KCNIP3,RYR3,ATXN2,TNFRSF19,SUPT20H,FERMT1,FNDC3A,CNKSR2,NUBPL,WDR37,PPP4R3A,SLC6A8,SLC12A2,SNRPN,FAM126B,TRERF1,BDP1,KDM4C,ERC1,PEG10,RBM26,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,COBL,ALG1,DMXL2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,FAM200B,SIRT1,ZFPM2,ITGB3BP,ZNF106,AKTIP,SLC44A1,TLR4,NPL,RGMB,SYNPO2,TRIO,GORASP1,FLRT2,USP1,WIPF1,XPO1,KCNT2,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,URM1,KCNAB1,DOCK8,FBXO36,ACTR3B,NETO1,CPNE4" MicroRNA hsa-miR-335:mirSVR_lowEffct hsa-miR-335:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-108 6.52E-105 3.38E-107 3.11E-106 310 1963 "KDM5D,NDRG3,ADCY6,PTCHD1,INTS2,KLHL13,RTL9,OSBPL6,AK2,ZNF578,UNC79,GPRASP2,AMPH,OGT,EP400,MAP4K3,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PARG,MAGEE2,APOC2,PPFIA3,CASK,TMEFF1,MARCH3,SLC4A4,EIF4G3,ALDH7A1,BARD1,MIR9-3HG,BMPR1B,CACNA1G,CACNB4,CALM1,CAMK2G,RUNX1T1,NFS1,CBS,KRIT1,METTL6,RGN,SCARB1,ENTPD6,ARHGEF2,SEPT7,LOC730101,CLGN,NUMBL,CHGB,MS4A7,EPS15L1,CLTC,AKAP7,PCYT1B,SUMF2,COL9A1,AKAP5,SMARCAL1,C2CD2,RBM39,CRMP1,GDA,CLIP3,SOCS5,PLXNA4,UBXN2A,PLCXD3,GREB1,PUM1,DCAF4,BOC,HDAC9,MYADM,ARHGAP32,RIPOR2,ARHGAP24,EARS2,LIN54,KCTD8,ARMCX2,FBXL5,ALKBH8,SNAP91,DOCK2,DTNA,PHC2,HIPK3,CELSR3,FAM13A,KMT5B,KCTD3,EIF4G2,STARD3NL,DCTN4,ENO2,EPB41L2,RCAN2,RASGRP2,GPHN,NCALD,APC2,CORO2B,CHST15,ZNF589,MED12L,FGF12,FGFR1,SYNCRIP,RGPD5,SLC37A3,SPECC1,PDLIM5,ERGIC3,KHDRBS3,CSPG5,MSANTD4,ABLIM2,OGA,FAM120B,DISC1,ALDH1L1,NFU1,PCDH17,TOX3,TNRC6A,GLUL,DCLK2,GNG4,FUT10,CCDC184,STON1,TMEM121B,PCLO,ZNF496,LINC01089,CLASRP,AP4S1,MAP4K5,IRAK3,PACSIN2,HLF,ELOVL5,SMAP1,IRF8,MSL1,IDH3A,ITGAM,ITPKB,KCNH2,IPO5,CYP27C1,LIMS1,SYTL4,HECTD2,NCOA7,MAP2,MARK1,MBNL1,LRP1B,MEIS1,KITLG,SCAMP5,MMP16,ADAM22,ZNF862,NDP,SFR1,NFE2L2,DNHD1,OCRL,P2RX7,PCDH8,PDCD2,PDE4D,GNG2,CYTL1,PFKFB3,ZDHHC8,NALCN,ZNF655,XRN1,FAM216A,PLCB2,SLC25A23,MTRF1L,STRN3,SCHIP1,SH3KBP1,POU6F1,PPP1R1A,GRAMD1C,CNNM2,SAMD9,CYBC1,BDNF-AS,MTMR10,PTN,TMEM260,PTPRB,EML5,TUG1,PPP2R3C,USP47,RAD51D,NWD1,OXR1,RASGRF1,KHDRBS2,MRPS18A,RIC8B,NUDT11,CARF,PNMA8A,GSTCD,KIRREL1,ROBO2,CCDC25,YY1AP1,RPE,HUNK,KCNIP3,ZNF354C,NCBP3,SATB1,SCN8A,SCP2,RASA3,KIF21A,SH3GL3,PPM1E,FHOD3,R3HDM2,SLA,FAM81A,EPN2,WDR47,LGI3,CDK5RAP2,INTS9,INAVA,LIMCH1,RBM34,KDM4B,ZNF423,ZC3H13,SPTAN1,ZNF621,TROVE2,ITPRID2,SS18,TTBK2,KANK1,ZC3H4,SYNE2,RHBDL3,PLCB1,SYN2,TACR1,CAMTA1,AGTPBP1,TBCEL,FBXW11,TCF12,SYNE1,PCDHB6,GPRIN3,RNF216P1,SIRT1,ZNF106,TIAM1,TMPO,RIMBP2,PIK3R5,C9orf85,RGMB,RUSC1,TSC1,PRR18,ZKSCAN5,CLHC1,BCL2L13,LMF1,RICTOR,PCDH20,MICU3,ZNF70,LYPD6,REEP1,POLR3H,FTSJ1,EMSY,MFF,PRTFDC1,EVI5,RNF103,CIAPIN1,SIGLEC10,WNK3,AMN1,ST7,MARCH8,UBE3B,KAT6A,HNRNPA3,JMJD1C,TTC7A,FRMD6,IFT88,GAN,PRRT4" MicroRNA hsa-miR-155:mirSVR_lowEffct hsa-miR-155:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-108 6.64E-105 3.43E-107 3.15E-106 300 1841 "RALGAPA1,SYN3,ABHD6,KLHL32,GALNT13,ESYT2,BEND6,DPY19L2P4,ZNF608,HACE1,ZNF578,TAOK1,ADGRF5,PCDH10,SYT13,DPP10,LRCH2,C6orf89,UPRT,DDO,PPP4R4,CASK,ARNTL,ARRB2,ZSCAN18,SLC4A4,ATP2A2,MPDZ,BCHE,SGCE,LDLRAD4,CA8,CA12,CALB1,CALM1,SPAG9,LRBA,CDH2,ZMYM4,LRRFIP1,ZNF445,CDO1,DIS3L,MS4A7,NGEF,FBXO7,HECTD1,CNR1,IQCK,ARMC8,AKAP5,RCHY1,SMARCAL1,PREPL,CREM,AKAP12,TRIM69,CRYM,CSF1,OSBPL3,SUSD5,IPCEF1,VAC14-AS1,SLITRK5,PITPNM3,PLCXD3,SEC14L5,CYBB,HDAC9,RIPOR2,RASSF2,KIAA0586,DNAL1,RHOBTB1,SPOCK3,WDR20,CHRDL1,EXOG,DMD,CPEB2,SLC12A6,CASP8AP2,DRP2,RCAN1,PHC2,CNNM1,MRO,EGR3,AASS,COPS4,ANKMY1,RRAGB,ADGRV1,EZH1,TAOK3,SCML2,MED12L,POLK,MEX3B,IP6K2,FOXO3,C2orf88,FYN,RAPGEF6,ARFIP1,MMADHC,USP19,PPARGC1A,TXNL4A,TCERG1,SPIN1,RAB30,HTATSF1,LUZP2,FERMT2,ADGRA3,STON1,GPR34,GPR37,PCLO,PRDM5,BTN2A1,ZBTB49,TOX2,ELOVL5,GABARAPL2,HMGCR,ZDHHC15,IGF1,ZIC5,LRRCC1,IL12A,ZNF678,LRRTM1,JAK2,KCNN3,KIF2A,KPNA5,LIFR,SYTL4,MEST,PPM1L,POC1B,COL28A1,SAMD5,N6AMT1,NDP,ALDH1L2,NFYA,CNOT4,NOVA2,NRCAM,CLDN11,GPR137C,PAX6,DPY19L2P2,PCSK5,PDE4B,PDPK1,ABCB1,SEMA5B,PIK3R1,CCSER2,SNX10,XRN1,GPSM2,PLCL1,JAKMIP1,PCDH18,PRIMPOL,PMP22,LRP12,EXOSC10,SCHIP1,ING3,PPARA,TATDN3,PPP2R5E,PPP3CA,KANSL1,RANBP3L,PRKAB2,PRKCB,MAPK9,HYDIN,WBP1L,GDPD2,PIGG,NCR3LG1,STK32A,EML5,PTPRE,ACSM5,PID1,CEP97,ACSS3,ZNF793,SH3TC2,FAT4,RAP1GDS1,ZNF493,OXR1,ZDHHC14,MSANTD2,TRIM68,RET,SLC25A36,RIC8B,GSTCD,ROBO1,SPIN3,GLDN,LRRK2,MEG3,RXRA,AP1AR,SALL1,SEMA6D,SCP2,GALNT10,SUPT20H,HSPA4L,SGK1,SH3BP2,SH3GL3,KIF16B,SHC4,FNDC3A,DHX30,SLC6A11,ELMO2,CPEB4,MYH15,DOP1A,PDZD2,KDM3A,MYCBP2,PEG10,ITPRID2,LARP4,SS18,ELOVL4,DIP2A,KLHL7,COBL,ASTN2,TACR1,ANKRD12,PJA1,MCF2L,DNMBP,PDLIM2,AGTPBP1,TCF4,DMXL2,SATB2,TRIM2,PHF24,FAM200B,DICER1,SIRT1,ZFPM2,AP4E1,SLC44A1,TK2,NR2E1,ERCC6L2,NR2C2,SYNPO2,ZNF610,UBE3A,FLRT2,ZNF709,WIPF1,XRCC4,PCDH20,ZNF711,MICU3,ATP6V0E2,TMEM237,AMZ1,DPYSL5,SPIRE1,SMARCAD1,EMSY,CADM2,STOX2,TMEM178A,CIAPIN1,WNK3,WNK2,FZD3,UBE3B,SMIM8,PHTF2,KLHDC1,NETO2,ST8SIA2,SRGAP2B,CPNE4" MicroRNA hsa-miR-105:mirSVR_highEffct hsa-miR-105:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-108 8.72E-105 4.47E-107 4.12E-106 265 1437 "RALGAPA1,ACADM,ADD2,KIAA1211,TXNDC16,SPARCL1,ABCD2,ZNF687,AMPD3,OGT,DPP10,EP400,MAP4K3,APBA2,USP37,SEMA4G,STK33,ZBTB10,NCOA1,NUMB,RASL11B,BACH1,RGS9,BLM,DST,ARHGEF7,SCAPER,CALM1,CAMK2G,SLC25A14,CLDN10,LDB2,KRIT1,USP6,USP2,CDH2,ZMYM4,MAGI1,TIGD7,CFL2,SRSF11,CHN2,SLIT2,NGEF,ABCG2,CNN3,IQCK,COL9A3,ZFP28,PREPL,CREM,ANKRD44,SLITRK5,ARHGEF4,RIPOR2,ARHGAP24,ZFYVE16,KIF26A,MAML1,PABPC5,GIT2,PITPNC1,JAKMIP2,RHOBTB1,SGSM2,WDR20,FAM107B,EXOG,GRIN3A,PDCD6IP,ECM2,DNAJB6,GOLT1B,HIPK3,CNNM1,YAF2,PHF20L1,MBNL2,EIF4G2,COPS4,PLEKHA1,PAN3,LRRC17,EPHB1,CEP85L,EXTL2,RPS6KC1,SH3YL1,SCML2,DLC1,FDFT1,SEC24B,SPSB4,FGFR1,AMOTL2,FHL1,SYNCRIP,SLC37A3,NBEA,HVCN1,UFM1,ATP2C1,CELF1,MSANTD4,AP4B1,GAD1,GALC,DISC1,KIAA1841,PPARGC1A,MALT1,TCERG1,COPS8,DBF4,SPIN1,GLI2,RAB30,MSL3,KDM2B,POLL,DCLK2,FERMT2,FUT10,LPAR4,PCLO,ATP2B1-AS1,GRIA2,PRDM5,BTN2A1,MIER3,HLF,GABARAPL2,HSF2,LRRCC1,ZNF678,KIF2A,LAMP2,PAXBP1,SYTL4,MAP2,MAT2A,MEF2C,MITF,AFDN,MPP2,MSR1,MT1M,MXI1,MYO9A,FXYD7,NEK1,NFE2L2,CNOT4,SLC11A2,NTRK2,NUCB2,CHAMP1,OGG1,OXTR,GPR137C,PCDH9,PDE1B,GPR85,GNG2,PFKFB4,FAM218A,PLCL1,PCDH18,MAPKAP1,EPB41L4B,TATDN3,PPP3CA,PKIA,DIRAS2,RELN,MTMR10,PTN,ZSCAN32,PTPN13,PTPRG,QDPR,CEP97,FAT4,RAP1GDS1,RBBP6,REV3L,GTDC1,ZNF532,ELP2,CCDC102B,MRAP2,NEK11,ARMH4,ZC3H14,MCMBP,GLDN,RPS20,ABCA11P,CLIP1,FNIP1,TRA2B,HKDC1,FNDC3A,SEC31A,CCDC88A,SLC12A2,ATF7IP,CXXC4,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,SNRPN,DOK5,KDM4C,TEX2,RBM26,TROVE2,ITPRID2,ZNF302,NKAIN2,ELOVL4,KLHL7,VPS13A,COBL,C12orf76,PJA1,CAMTA1,EXOC7,TBCEL,SIN3B,ZEB1,SZT2,NSD1,RNF216P1,ZFPM2,SLC44A1,TIAM1,MTMR14,FAM124A,R3HDM1,TPM1,SYNPO2,AMACR,PPIL6,TTC3,HIRA,RPL7L1,FAM155A,FLRT2,PLEKHH2,XRCC4,ZIC1,ZIC2,ZNF189,EMSY,PRDM8,NAV3,EPM2A,HNRNPA3,NETO1,SRGAP2B,SPATA13,SENP7" MicroRNA hsa-miR-299-3p:mirSVR_lowEffct hsa-miR-299-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.91E-108 1.07E-104 5.44E-107 5.01E-106 276 1562 "RALGAPA1,ASIC1,SYS1,FMNL2,GALNT16,ADCY6,ADORA1,RNF150,LRFN2,DPY19L2P4,KIAA1324,WDR35,OSBPL8,SEMA6A,ALCAM,PCDH10,AMPD2,LRFN1,SEMA7A,CCDC146,MAP4K3,PKP4,FAM131A,CDC14B,SEMA4G,IGDCC4,TMEFF1,ARNTL,ARRB1,MARCH3,NUMB,SLC2A11,BID,KSR1,BTK,GPC2,WASF1,CA8,HAP1,CAST,ISPD,KYAT1,KRIT1,MTMR7,CDC25B,ARHGAP33,EVI5L,MAGI1,COPB2,PLEKHB1,LHX2,QKI,SULT4A1,IGLON5,CNTFR,MAGED1,IGDCC3,CLOCK,CREM,CLIP3,CSF2RA,CST3,FAM169A,ARHGEF4,FAM131B,CCDC144A,DOCK4,HDAC9,MYADM,ZFYVE16,EARS2,INTS1,SCRN1,GIT2,ELMSAN1,HEPH,ELMO1,TIAM2,DDX46,SPOCK3,CD99L2,DYNC1I1,DMTF1,PDCD6IP,ARRDC4,ECM2,DNAJB6,DNM1L,EDN3,EDNRA,EDNRB,CNNM1,YAF2,APH1A,EGFR,EGR3,GOLGA7,IRAK4,RGS17,USPL1,EPB41,MTSS1L,GPHN,IGSF6,CEP85L,ZNF549,EYA1,EZH1,REEP2,CORO2B,CEP78,FCGR3A,KAT8,PPP1R1B,SLC9B2,FER,OLFM1,FGF11,BAIAP2,AMOTL2,HPCAL4,IP6K2,JKAMP,SMC2,ATP2C1,ZNF605,ERGIC3,CSPG5,STAU2,MEGF11,MEGF10,CHL1,RAPGEF6,C15orf41,KIAA1841,MSTN,USP19,TOX3,TNRC6A,MSL3,ZNF638,MAP7D2,GRIA2,RABL2A,FAM107A,GUCY1B1,PADI2,ZDHHC15,CPT1C,DHX35,IGF1,LRRCC1,SCIN,INSM1,KCNJ16,CREG2,L1CAM,LAMP2,LIFR,MARK1,MBD1,MEST,MID1,GIT1,MSI1,P2RY13,SFR1,NME4,SLC11A2,NTRK2,NUCB2,LOC100128398,OXTR,P2RY1,CNTN3,CDK18,PDE4D,ENPP2,XRN1,KCTD15,PLCB2,PLIN1,PDZRN4,STRN3,PPARA,NKAIN4,CEP41,HYDIN,MASP1,RELN,LAMA1,TMEM104,CNTLN,BDNF-AS,PTPRN,PTPRO,SH3TC2,RASGRF2,ZDHHC14,GTDC1,UBR7,RIC8B,KLHDC8A,ALG9,ROBO2,NEK11,ZNF671,MCMBP,SGSM1,ADAL,ZNF331,CSRNP3,ASAP3,ELMO2,ATF7IP,MAST1,SNRPN,PDZD2,KDM4C,PEG10,ZBTB43,TSPYL2,ATP10B,CLSTN2,CAMTA2,POGZ,DIP2A,STX1A,KANK1,ARHGEF9,MTCL1,MLST8,SIN3B,SATB2,TRIM2,RPGRIP1L,NAT16,DOCK9,NSD1,PUM2,TNS2,CYB561A3,PMS2CL,TMEM9,FAM124A,R3HDM1,TPM1,SYNPO2,TRPS1,SSBP2,UBE3A,PLEKHH2,ZNF709,VLDLR,WIPF1,RICTOR,LGI4,ZIC1,ZIC2,TRIM9,LYPD6,DPYSL5,DHX33,SLC30A4,NT5M,DNALI1,GDPD5,LINC02210,GAL3ST3,PARP11,RGS7BP,ST7,ACTR3B,NETO1,GAN,SPATA13" MicroRNA hsa-miR-519d:mirSVR_highEffct hsa-miR-519d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.59E-108 1.45E-104 7.37E-107 6.78E-106 265 1440 "KCNH8,NCKAP5,SLC24A4,ABCD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,LINC00173,STK33,RASL11B,SLC4A4,ATP1B3,DPY19L3,ADGRB3,NRP2,SCAPER,MTMR3,JAZF1,CALB2,USP6,C1orf52,TIGD7,CLGN,CFL2,TAOK2,EPS15L1,ABCG2,AKAP5,AHCTF1,CNRIP1,CPS1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,HDAC9,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,ZC3H11A,PLPPR4,SACS,USP3,DMTF1,DPYSL2,DNAJB6,DNM1L,E2F5,SNX29,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,GMPR2,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,ZMAT1,GABBR1,B4GALNT1,ERAP1,SYT17,DISC1,PPARGC1A,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,CIT,AP4S1,IRAK3,HAS2,MSL1,METTL21A,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NACA,NCF2,SFR1,NELL2,CNOT4,OCRL,OGG1,OPA1,GPR137C,CNTN3,PDE1B,ZDHHC8,CCSER2,JAKMIP1,RETREG2,EPB41L4B,DRAM2,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,PTPRD,PTPRO,CEP97,USP47,FAT4,OXR1,RASGRF2,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,BTBD3,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,MBD5,CMTR2,SNRPN,RBM34,USP33,SOX3,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,PCDHB10,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,UCHL1,CCDC14,VLDLR,TBC1D15,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,DPF3" MicroRNA hsa-miR-370:mirSVR_lowEffct hsa-miR-370:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-108 1.54E-104 7.77E-107 7.16E-106 312 1994 "DGCR6,KCNH8,SYN3,ASIC1,NCKAP5,SYS1,XKR4,ADCY6,PWWP2A,CC2D2A,AK2,ZNF578,TAOK1,ARHGAP20,CARNS1,CDC42BPA,EP400,MYH7B,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,APLP1,APOC1,TNRC6C,USP37,CPNE5,AQP6,CDK10,SFMBT2,ARHGDIA,TMEM108,SLC2A11,ADAM15,BACH1,LINC00847,SEC11C,RGS9,BCL7A,CFLAR,KSR1,SYNJ1,SYNJ2,MTMR3,JAZF1,CA12,KALRN,VXN,SPAG9,RUNX1T1,ZNF501,SCARB1,SYNGR3,TIGD7,CCPG1,NOG,CRLF1,SRSF11,ASIC3,RAB33A,QKI,MAP4K4,AKAP5,SLC4A8,CLOCK,CREM,SH2B1,HAPLN1,CRY2,ANKRD44,CS,GALNT9,VCAN,RASGEF1C,PLCXD3,CTH,GREB1,RIMS2,CYBB,ARHGAP32,ZFYVE16,EARS2,TM9SF4,LIN54,MAML1,TMEM170A,DAPK1,SPOCK2,IP6K1,GIT2,SPATA2,HEPH,TIAM2,FBXL5,TMEM130,GUCD1,ALKBH8,POM121,RHOBTB1,SGSM2,TMCC2,WDR20,KIF19,DTNA,DTNB,ECM2,E2F6,EDN3,PHC2,RASGRP1,EGFR,GOLGA7,KCTD3,COPS4,PLEKHA1,PAN3,EPB41L2,MTSS1L,SRRM1,ZNF549,ANKMY1,KATNAL1,ARMCX1,CHST15,FCGR3A,SLC9B2,FGF14,TMEM164,POLK,SEMA4D,FLNC,FLT1,EFCAB2,ZNF605,HHIPL1,GAD1,ZNF274,GHDC,TMEM8B,DISC1,ALDH1L1,ARFIP1,FREM1,CSDC2,LYVE1,RUNDC3A,ZNF276,ZNF638,ZNF782,STON1,CACFD1,CIT,CLASRP,RNF165,RABL2A,ADAMTS6,FRMD5,ELOVL5,IGFBPL1,DHX35,ICA1,EID2B,RBPJ,LRRCC1,DISP2,IL6ST,KCND2,GPR62,GATD1,KIF5A,A1BG-AS1,IPO5,STXBP5,LIG4,PAXBP1,SMAD1,MAP4,MBD1,MEIS1,MEST,AFF1,MMP16,GIT1,DBNL,NRBP2,N6AMT1,LYRM9,LAYN,MYO6,MYO9A,NEFM,SMIM11A,NTRK2,TBC1D25,OCRL,LOC100128398,PDE1C,GNG2,PFKFB4,XRN1,PLIN1,PNMA3,POLR2F,DRAM2,PPP2R5E,RASGEF1B,WBP1L,CYBC1,DEF8,MTMR10,PTPRE,NKAIN1,TUG1,CEP97,CCDC40,RBBP6,RFX2,RGS3,RGS4,ZFHX4,C12orf49,KLHDC8A,ARMC5,CCDC25,ELP2,NEK11,BAALC,SPIN3,KIAA0895L,GLDN,STK32B,ZNF568,ZNF331,SARS,SCN2B,SCN7A,PEAR1,GALNT10,STUM,FOXRED1,MRAS,SCAF8,FAM102A,HKDC1,ST6GAL1,ANKRD6,NUBPL,DHX30,SLC9A5,TET1,ZFP1,GKAP1,MYH15,KDM4B,ZSWIM8,IZUMO4,ZC3H13,DBNDD2,CLASP2,ZC4H2,SSPO,MPRIP,STAU1,NEK4,SEPT8,PHLDB1,NUDT10,COBL,TAF9,EXOC7,TCF12,SYNE1,NAT16,USP32P1,CYB561A3,DICER1,ZFPM2,ITGB3BP,SLC44A1,THRA,NR2E1,FAM124A,RIMBP2,R3HDM1,TP53BP2,CDK20,ELP5,AMACR,KCNE5,TSC1,UBTF,VIPR2,VLDLR,WNT7A,KLC2,XRCC4,ZFP37,ZIC2,ATP6V0E2,AMZ1,GAL3ST3,NAV3,URM1,FIP1L1,ITM2C,FAM47E,MRPL47,RTN4,KAT6A,SMIM8,FBXO36,FAM219B,MSRB3" MicroRNA hsa-miR-543:mirSVR_highEffct hsa-miR-543:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.32E-108 1.86E-104 9.29E-107 8.55E-106 287 1693 "KCNH8,ACADM,CLK4,C3orf14,FMNL2,GALNT13,BRAP,ADORA2A,PWWP2A,ZNF608,KLHL13,OSBPL1A,OSBPL8,C1QTNF3,SRPX,ABCD2,FAM135A,PARG,DDO,CDC14B,CASK,ZFYVE28,LINC00173,MARCH3,STX16,ADGRB3,SEC11C,DST,SYNJ1,SCAPER,CASTOR3,JAZF1,WASF1,CALB1,CAMK2G,SPAG9,C1orf52,ARHGEF2,CDH2,ZMYM4,LRRFIP1,L3MBTL4,DIS3L,RCBTB2,CHN1,CHN2,NRXN3,NGEF,QKI,AKAP7,ARMC8,AKAP6,AKAP5,SLC4A8,GAL3ST1,AHCTF1,MYRIP,ZNF521,SLC35F1,CLOCK,C2CD2,ENTPD4,HAPLN1,RNF14,GDA,MROH8,OSBPL3,SUSD5,VCAN,SOCS5,PHF14,CTH,CCDC144A,GAPVD1,ZFYVE16,MATR3,DGKB,PABPC5,GIT2,ELMSAN1,HEPH,FBXL5,ZC3H11A,DDX46,RHOBTB1,SACS,SPOCK3,SEC16A,DLX1,GRIN3A,HS3ST2,NR1D2,CPEB2,DTNA,GOLT1B,EDNRB,KLHL5,SUGP2,GOLGA7,ASB3,PLEKHA1,PAN3,EIF1,EMX2,VPS13B,EPHB1,GPHN,STX2,DENND4A,CDKL3,ADGRV1,EYA1,CLVS1,FAM198B,TMEM132C,FDFT1,GORAB,SEC24B,FGF12,FGF13,PCYOX1,RGPD5,NELFCD,ST6GALNAC3,FYB1,GATM,ARFIP1,GGT7,PPARGC1A,TCERG1,SPIN1,TOX3,ZNF638,RAB40B,GNAO1,ADGRA3,DIDO1,GRM8,CIT,BTN2A1,PSIP1,FAM222A,HMGCR,HNF4G,NEGR1,HSF2,MSL1,SOWAHA,INPP1,SLC35G1,METTL21A,CREG2,IPO5,LAMP2,PAXBP1,HECTD2,NCOA7,MARK1,LYPLAL1,MATN2,MEIS2,KITLG,MSR1,MYCN,NELL2,CNOT4,NRCAM,GPR137C,GLIPR1L2,PCDH8,PCSK1,PRTG,SERPINI1,SMIM7,SCHIP1,SH3KBP1,PPARA,PPP2R2C,CEP41,GRAMD1C,CNNM2,PTCH1,ELOVL2,SPDL1,TMEM260,PTPRB,PTPRD,PEX2,QDPR,PID1,TMEM255A,RAD17,ZNF793,PBRM1,ZFHX4,GSTCD,CYB561D1,ROBO2,FBXW7,ATP8B4,LRRK2,PTGR2,ABCA11P,CLIP1,RTN1,CCDC112,LRFN5,SCN8A,SCP2,SEC14L1,SGK1,FHOD3,CNKSR2,BTBD3,SLC11A1,NAPB,CPEB4,ZNF667,ANKRD36,SNAP25,MBD5,LMBRD1,SNRPN,FNBP1,UHRF1BP1L,KDM4C,TEX2,PEG10,ZBTB43,RBM26,LMO3,TROVE2,RGL1,KANK1,PRRC2C,VPS13A,MTCL1,DMXL2,TRIM2,SYNE1,PCDHB6,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIRT1,ZFPM2,AP4E1,SYNPO2,PDSS1,RUNDC3B,ANKRD20A2,TTTY15,SGK3,UBE3A,OSBP2,PLEKHH2,CCDC14,WIPF1,XRCC4,PCDH20,ZIC1,ZIC2,ZNF74,LYPD6,REEP1,EML6,ANKS1B,LAMP5,ZFAND5,EMSY,CADM2,EVI5,LINC02210,PRDM8,HPS4,EPM2A,SMIM8,NETO1,RNF146,CPNE4,SENP7" MicroRNA hsa-miR-514b-3p:mirSVR_lowEffct hsa-miR-514b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.32E-108 1.86E-104 9.29E-107 8.55E-106 281 1623 "RALGAPA1,CLK4,TMCC3,BRAP,KIAA1211,BEND6,AP2A2,MTUS1,KLHL13,PCDH19,HACE1,WDR35,SEMA6A,ALCAM,MARCH4,PCDH10,BBOX1,UNC79,FAM135A,GPRASP2,LRCH2,C6orf89,LCORL,PKP4,UPRT,NT5C3B,PHYHD1,USP37,PPP4R4,RGS20,CADPS,LINC00173,TMEM108,ATP1B3,ATP2A2,ALDH7A1,ADAM23,LINC00847,BCHE,BMP7,SYNJ2,SCAPER,C5,IL33,ISPD,CLDN10,USP6,MTMR7,MAGI1,SOCS6,MS4A7,CNOT8,IGLON5,ARMC8,AKAP6,MAGED1,ZNF521,FAM171B,C2CD2,CREM,GDA,SNCAIP,RGS6,ARHGEF10,VCAN,PPP1R16B,ERC2,PUM1,KATNAL2,DCAF8,MATR3,DNAL1,JAKMIP2,HEPH,FBXL5,GSDME,SGSM2,DLX1,EXOG,SLC29A4,DMTF1,DPH1,DTNA,TOM1,ABCC5,DNM1L,EDN1,EDN3,FCF1,TMTC1,FSD1L,EIF5,MRNIP,CALCRL,EIF1,EMX2,RCAN2,EPHB1,DENND4A,NCALD,ZNF549,MRPL37,ETV1,KATNAL1,TAOK3,FCGR1A,CEP78,FDFT1,ZNF589,PRKAG2,MEX3B,SMC2,ATP2C1,KHDRBS3,ABLIM2,OGA,GABRG2,ZNF234,SYT17,C15orf41,DISC1,INPP5K,IGSF5,GCNT2,MSTN,ADAM28,TNRC6A,ZNF638,GNAL,GPD2,PRUNE2,CCDC184,GPR34,PCLO,FAM19A2,ZBTB49,ZHX1,BACH2,HSPA1L,MSL1,ZNF546,RBPJ,KCND2,KIF5A,IPO5,STXBP5,LAMA2,STMN1,SFXN5,SYTL4,LSS,MBD1,MBNL1,LRP1B,ZNF680,GIT1,HS6ST3,MYT1,HNRNPM,SFR1,NOVA1,NPTX1,SLC11A2,NRCAM,NUCB2,OCRL,CHAMP1,PCDH8,PCSK1,PDE4D,SLC10A4,SERPINI1,XRN1,PLCB2,ING3,PPP2R2B,PRKAB2,PKIA,PRKAR1B,PRKCB,MAPK4,MAPK9,PRPSAP2,VPS13C,CNTLN,PTPRE,PTPRN2,PTPRO,FAT4,RGS3,RIC8B,RPL15,ZNF671,LRRK2,ATAT1,TRAPPC13,SEMA6D,SUPT20H,TRA2B,PPM1E,CPEB3,FHOD3,ST6GAL1,PPP4R3A,ZNF430,SLC9A5,ATF7IP,IFT122,ANKRD36,SNAP25,MBD5,LMBRD1,SNRPN,USP33,SP4,MYCBP2,TEX2,ZNF423,ZBTB43,RBM26,POGZ,SAMSN1,SSPO,PHLDB1,KANK1,SULF2,SYPL1,TACR1,PJA1,TAL1,TCF4,PHF24,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,SIRT1,AP4E1,SLC44A1,TIAM1,RELL2,BHLHB9,BEX4,CSMD1,PIK3R5,TP53BP2,SYNPO2,AMACR,ANKRD20A2,TTC3,GORASP1,BCL2L13,GUSBP1,ZBTB14,ZIC1,ZNF708,KCNT2,TCEAL7,POLR3H,DPYSL5,EMSY,SLC38A1,LINC02210,HPS4,SLC17A7,PDSS2,SMIM8,FBXO36,KLHDC1,FRMD6,IFT88,NETO1,GAN,FAM198A" MicroRNA hsa-miR-224*:mirSVR_highEffct hsa-miR-224*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.54E-108 1.98E-104 9.84E-107 9.06E-106 282 1635 "RALGAPA1,KCNH8,CLK4,NCKAP5,XKR4,FMNL2,CCDC85A,PLEKHH1,KIAA1211,BEND6,MTA3,SLC24A4,CASKIN1,OSBPL6,ALCAM,CDC42BPA,DPP10,LRCH2,LCORL,PKP4,CASK,ATP2A2,BLM,ST3GAL5,MTMR3,MTMR2,RAB29,KALRN,VXN,SPAG9,NFS1,CCNH,C1orf52,LRBA,L3MBTL4,DLGAP1,UBE2L6,RCBTB2,SRSF11,CHGB,C4orf33,CNR1,CNTN1,ARMC8,AKAP6,ABI3BP,RTTN,ZFP28,PREPL,ENTPD4,RBM39,HAPLN1,HINFP,ANKRD44,SNCAIP,VCAN,SOCS5,PLXNA4,SLITRK5,ARHGAP24,LIN54,MATR3,KCTD8,DAPK1,ARMCX2,ZBTB24,MYEF2,ZC3H11A,RHOBTB1,SNAP91,GRIN3A,DMD,NR1D2,DMTF1,SLC12A6,CASP8AP2,DPYSL2,DTNA,FAM78B,DNAJB6,SEMA3D,APH1A,MBNL2,KMT5B,EGR3,AASS,GOLGA7,IRAK4,PLEKHA1,EIF1,EPB41L2,LRRC17,ZNF549,ETV1,VPS26C,ADGRV1,EZH1,F5,ARMCX1,CLVS1,ACSL4,DLC1,CHST15,FDFT1,FER,OLFM1,FGF11,FGF12,PRKAG2,SUCO,SYNCRIP,FLT1,NBEA,SMC2,CSPG5,NSG1,RAPGEF6,DISC1,LRRC37A6P,SULT1C4,SESN1,PCDH17,COPS8,SPIN1,TNRC6A,GLUL,ZNF638,PRUNE2,STON1,GPR34,PCLO,RNF165,ZBTB49,UBE2QL1,MIER3,CELF5,MSL1,IDH3A,SOWAHA,GAREM2,RBPJ,FAM69A,SLC35G1,KCND2,KCNJ16,KCNN3,CREG2,KIT,CYP27C1,STMN1,NCOA7,MATN2,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,ADAM22,ZNF92,MYO9A,HNRNPM,NDP,SLC11A2,TBC1D25,IGSF11,PRTG,PDE4D,ZFYVE21,TRHDE,EXOSC10,ING3,EPB41L4B,PPM1B,PPP2R5E,PRKACB,DCHS2,SNRK,TMEM260,PTPRB,PTPRE,PEX2,ACSM5,CCDC40,SH3TC2,OXR1,RASGRF1,HKR1,RDX,KIF7,LGI2,CCDC82,ZNF532,CCDC25,RORB,RPL15,ZC3H14,ZNF671,MCMBP,LRRK2,MEG3,CLIP1,ZNF331,SALL1,ATXN7,FNIP1,RASA3,SGK1,KIF21A,PPM1E,SHC4,FNDC3A,FAM81A,DHX30,CCDC88A,BTBD7,SLC22A4,CDK5RAP2,RCOR3,SNAP25,SNCA,MBD5,SNRPN,NMNAT2,HECW1,MYCBP2,KDM4C,TEX2,LMO3,PBLD,POGZ,SAMSN1,DIP2A,SULF2,VPS13A,ADAMTS17,SYN1,COBL,C12orf76,MTCL1,CAMTA1,TCEA1,ZEB1,RPGRIP1L,SYNE1,SLC19A3,SIRT1,AP4E1,TIAM1,TK2,BHLHB9,KAT6B,CDK20,RUNDC3B,PRR18,TUBB1,FAM155A,UBE2H,LAT2,CLDND1,XRCC4,PCDH20,ZIC1,ZIC2,KCNT2,LYPD6,ZNF177,UPF3A,MAP3K12,LINC02210,ADAMTS9,TMEM178A,MDH1B,WNK3,PDSS2,EPM2A,DNAH10,FAM13C,MRPL47,JMJD1C,FRMD6,NETO2" MicroRNA hsa-miR-200b*:mirSVR_lowEffct hsa-miR-200b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-108 2.08E-104 1.03E-106 9.49E-106 291 1741 "VWA5B2,CLK4,RNF157,PWWP2A,BEND6,INTS2,HECW2,AK2,SEMA6A,ALCAM,SRPX,PCDH10,AMPH,ZFAT,CCDC146,PARG,APC,PPP4R4,CASK,TMEFF1,ARNTL,PCDHGB4,NUMB,INSYN2B,RNF182,ATP6V1G2,ADGRB3,NRP2,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,MTMR3,C5,RAB29,PTBP2,RUNX1T1,CD38,DCLK1,LRRFIP1,MAGI1,CCPG1,NUMBL,NDST3,PLAA,C4orf33,ARMC8,FAM149A,COL4A5,SUMF2,TOGARAM2,ZNF521,CPS1,CLOCK,RBM39,ANKRD44,GDA,TRIM69,CS,SNCAIP,LRRC3B,CSNK1G3,SIPA1L1,VCAN,APPL1,PNPLA8,PUM1,CCDC144A,TMEM170A,BRINP1,DNAL1,MFAP3L,KLHL3,SV2B,SPOCK3,CHRDL1,DMD,USP3,DTNA,EDNRB,FCF1,KLHL5,FSD1L,YAF2,PHF20L1,SUGP2,PLEKHA1,TUBD1,MTSS1L,DENND4A,ABCA8,ACSL4,CEP78,PRMT5,FER,FGF1,FGF12,IP6K2,SYNCRIP,IQCG,SEMA4D,FLT1,SLC37A3,TMEM107,PDLIM5,ATP2C1,CELF1,NSG1,MEGF10,GAD1,SIGLEC8,C15orf41,GATM,TUBGCP4,SESN1,FREM1,PCDH17,PPARGC1A,TCERG1,SPIN1,TOX3,MAP7D2,GRB10,GRIA2,DIDO1,BVES,AP4S1,PSIP1,GUCY1B1,RASSF8,HAS2,ZDHHC15,NEGR1,SMAP1,IRF8,MSL1,ZIC5,IL6ST,JAK2,SLC35G1,METTL21A,KCNN2,LAMP2,LIMS1,PAXBP1,SYTL4,CLEC18A,MAN2A2,MAPT,TM6SF1,SHC3,MSI1,ADAM22,MXI1,MYO9A,RTL5,NF1,GPR137C,CNTN3,PAX6,PCDHGC3,PCDH8,PCDH9,PDE4B,CYTL1,FAM98B,ZFYVE21,XRN1,FAM216A,JAKMIP1,PURG,PRIMPOL,PMP22,STRN3,LRP12,SCHIP1,PPARA,MINDY2,TATDN3,PPP2R2C,PRKACB,KLK6,VPS13C,WBP1L,SNRK,CNTLN,ANKHD1,ZIK1,PTPRE,ZNF615,FAT4,KHDRBS2,TRIM68,RIC8B,ZFHX4,CCDC82,EXD2,RPL15,BAALC,GLDN,SGSM1,STK32B,CLIP1,TRAPPC13,DGLUCY,SEMA6D,SATB1,ATXN7,PRCD,SCP2,TNFRSF19,CASC3,FOXRED1,ZFP30,KIF21A,PPM1E,ARX,R3HDM2,NLGN1,RADIL,CCDC88A,ELMO2,COA1,ANKRD36,SNAP25,FAM126B,PDZRN3,FNBP1,SOX11,NMNAT2,SAMSN1,ELOVL4,CEP68,SEPT3,SYNE2,NUDT10,PLCB1,SYPL1,SYT1,COBL,TAF9,TAL1,TBCEL,SIN3B,SATB2,ZEB1,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,SLC19A3,USP32P1,FAM200B,C18orf54,AKTIP,ERCC6L2,NPL,RGMB,SYNPO2,ANKRD20A2,UCHL1,FLRT2,CCDC14,VLDLR,RBFOX3,ZNF711,LYPD6,ZNF154,TMEM237,ANKS1B,CADM2,TMEM178A,FIP1L1,DNAH10,FAM13C,SMIM8,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-30d-5p:TargetScan hsa-miR-30d-5p TargetScan 4.11E-108 2.30E-104 1.11E-106 1.02E-105 237 1144 "ABHD6,ACTN1,ELFN2,RNF157,BRAP,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,EPB41L5,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B2,DPY19L3,BACH1,PROM1,KSR1,BMP7,FUBP1,CALB2,CARS,DGKI,EVI5L,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,LONRF1,MATR3,KCTD8,MAML1,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,DDX46,SACS,DMD,CPEB2,DPYSL2,DRP2,RCAN1,DTNA,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,RGS17,C3orf18,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,MED12L,AMOTL2,MEX3B,IQCG,FOXO3,CAMKK2,CELF1,NSG1,MSANTD4,HHIPL1,FYN,CHL1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GRB10,GRIA2,PRDM5,RNF165,MAN1B1,MIER3,HLF,ELOVL5,NEGR1,CELF5,CDH20,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MEIS2,MMP16,MOV10,ADAM22,MYO5A,NEFM,NF1,NFYA,NOVA1,OXTR,PDE3A,PDE4D,FAM216A,SDK2,EPB41L4B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,EPDR1,ANKHD1,PTPN13,OXR1,RASGRF2,PRRT2,GTDC1,FIGN,RFX2,RFX3,PBRM1,ALG9,CARF,RPS6KA2,SATB1,SBF1,SCN8A,PRCD,HSPA4L,PPM1E,FRMPD1,KIF16B,CPEB3,CHD9,FNDC3A,CNKSR2,NLGN1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,FAM126B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,NECAB1,MCF2L,SATB2,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,FAM155A,PCDH20,MKRN3,REEP1,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30a-5p:TargetScan hsa-miR-30a-5p TargetScan 4.11E-108 2.30E-104 1.11E-106 1.02E-105 237 1144 "ABHD6,ACTN1,ELFN2,RNF157,BRAP,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,EPB41L5,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B2,DPY19L3,BACH1,PROM1,KSR1,BMP7,FUBP1,CALB2,CARS,DGKI,EVI5L,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,LONRF1,MATR3,KCTD8,MAML1,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,DDX46,SACS,DMD,CPEB2,DPYSL2,DRP2,RCAN1,DTNA,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,RGS17,C3orf18,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,MED12L,AMOTL2,MEX3B,IQCG,FOXO3,CAMKK2,CELF1,NSG1,MSANTD4,HHIPL1,FYN,CHL1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GRB10,GRIA2,PRDM5,RNF165,MAN1B1,MIER3,HLF,ELOVL5,NEGR1,CELF5,CDH20,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MEIS2,MMP16,MOV10,ADAM22,MYO5A,NEFM,NF1,NFYA,NOVA1,OXTR,PDE3A,PDE4D,FAM216A,SDK2,EPB41L4B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,EPDR1,ANKHD1,PTPN13,OXR1,RASGRF2,PRRT2,GTDC1,FIGN,RFX2,RFX3,PBRM1,ALG9,CARF,RPS6KA2,SATB1,SBF1,SCN8A,PRCD,HSPA4L,PPM1E,FRMPD1,KIF16B,CPEB3,CHD9,FNDC3A,CNKSR2,NLGN1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,FAM126B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,NECAB1,MCF2L,SATB2,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,FAM155A,PCDH20,MKRN3,REEP1,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30b-5p:TargetScan hsa-miR-30b-5p TargetScan 4.11E-108 2.30E-104 1.11E-106 1.02E-105 237 1144 "ABHD6,ACTN1,ELFN2,RNF157,BRAP,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,EPB41L5,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B2,DPY19L3,BACH1,PROM1,KSR1,BMP7,FUBP1,CALB2,CARS,DGKI,EVI5L,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,LONRF1,MATR3,KCTD8,MAML1,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,DDX46,SACS,DMD,CPEB2,DPYSL2,DRP2,RCAN1,DTNA,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,RGS17,C3orf18,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,MED12L,AMOTL2,MEX3B,IQCG,FOXO3,CAMKK2,CELF1,NSG1,MSANTD4,HHIPL1,FYN,CHL1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GRB10,GRIA2,PRDM5,RNF165,MAN1B1,MIER3,HLF,ELOVL5,NEGR1,CELF5,CDH20,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MEIS2,MMP16,MOV10,ADAM22,MYO5A,NEFM,NF1,NFYA,NOVA1,OXTR,PDE3A,PDE4D,FAM216A,SDK2,EPB41L4B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,EPDR1,ANKHD1,PTPN13,OXR1,RASGRF2,PRRT2,GTDC1,FIGN,RFX2,RFX3,PBRM1,ALG9,CARF,RPS6KA2,SATB1,SBF1,SCN8A,PRCD,HSPA4L,PPM1E,FRMPD1,KIF16B,CPEB3,CHD9,FNDC3A,CNKSR2,NLGN1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,FAM126B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,NECAB1,MCF2L,SATB2,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,FAM155A,PCDH20,MKRN3,REEP1,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30c-5p:TargetScan hsa-miR-30c-5p TargetScan 4.11E-108 2.30E-104 1.11E-106 1.02E-105 237 1144 "ABHD6,ACTN1,ELFN2,RNF157,BRAP,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,EPB41L5,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B2,DPY19L3,BACH1,PROM1,KSR1,BMP7,FUBP1,CALB2,CARS,DGKI,EVI5L,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,LONRF1,MATR3,KCTD8,MAML1,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,DDX46,SACS,DMD,CPEB2,DPYSL2,DRP2,RCAN1,DTNA,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,RGS17,C3orf18,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,MED12L,AMOTL2,MEX3B,IQCG,FOXO3,CAMKK2,CELF1,NSG1,MSANTD4,HHIPL1,FYN,CHL1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GRB10,GRIA2,PRDM5,RNF165,MAN1B1,MIER3,HLF,ELOVL5,NEGR1,CELF5,CDH20,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MEIS2,MMP16,MOV10,ADAM22,MYO5A,NEFM,NF1,NFYA,NOVA1,OXTR,PDE3A,PDE4D,FAM216A,SDK2,EPB41L4B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,EPDR1,ANKHD1,PTPN13,OXR1,RASGRF2,PRRT2,GTDC1,FIGN,RFX2,RFX3,PBRM1,ALG9,CARF,RPS6KA2,SATB1,SBF1,SCN8A,PRCD,HSPA4L,PPM1E,FRMPD1,KIF16B,CPEB3,CHD9,FNDC3A,CNKSR2,NLGN1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,FAM126B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,NECAB1,MCF2L,SATB2,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,FAM155A,PCDH20,MKRN3,REEP1,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30e-5p:TargetScan hsa-miR-30e-5p TargetScan 4.11E-108 2.30E-104 1.11E-106 1.02E-105 237 1144 "ABHD6,ACTN1,ELFN2,RNF157,BRAP,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,EPB41L5,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B2,DPY19L3,BACH1,PROM1,KSR1,BMP7,FUBP1,CALB2,CARS,DGKI,EVI5L,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,LONRF1,MATR3,KCTD8,MAML1,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,DDX46,SACS,DMD,CPEB2,DPYSL2,DRP2,RCAN1,DTNA,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,RGS17,C3orf18,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,MED12L,AMOTL2,MEX3B,IQCG,FOXO3,CAMKK2,CELF1,NSG1,MSANTD4,HHIPL1,FYN,CHL1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GRB10,GRIA2,PRDM5,RNF165,MAN1B1,MIER3,HLF,ELOVL5,NEGR1,CELF5,CDH20,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MEIS2,MMP16,MOV10,ADAM22,MYO5A,NEFM,NF1,NFYA,NOVA1,OXTR,PDE3A,PDE4D,FAM216A,SDK2,EPB41L4B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,EPDR1,ANKHD1,PTPN13,OXR1,RASGRF2,PRRT2,GTDC1,FIGN,RFX2,RFX3,PBRM1,ALG9,CARF,RPS6KA2,SATB1,SBF1,SCN8A,PRCD,HSPA4L,PPM1E,FRMPD1,KIF16B,CPEB3,CHD9,FNDC3A,CNKSR2,NLGN1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,FAM126B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,NECAB1,MCF2L,SATB2,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,FAM155A,PCDH20,MKRN3,REEP1,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,FXR1,FRMD6,GAN" MicroRNA hsa-miR-891b:mirSVR_lowEffct hsa-miR-891b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-108 2.46E-104 1.18E-106 1.09E-105 273 1533 "NCKAP5,NDRG3,TMEM132B,GALNT13,ADD1,ADD2,AP2A2,PCDH19,SEMA6A,ARHGAP20,UNC79,DPP10,LCORL,PHF12,TNRC6C,USP37,SEMA4G,IGDCC4,ZFYVE28,MARK4,ZSCAN18,CCAR2,TMEM108,EIF4G3,RNF182,N4BP2L1,BARD1,MIR9-3HG,KSR1,DST,SYNJ2,FUBP1,SGCE,LDLRAD4,CACNA1A,KALRN,LRBA,SEPT7,LARGE1,MAGI1,MS4A7,LHX2,CLTC,QKI,SRP14-AS1,CNN3,ARHGEF6,ARMC8,RCHY1,TOGARAM2,FAM171B,CRHBP,RNF14,ANKRD44,NCOR1,GDA,SNCAIP,SEC24C,SIPA1L1,SLITRK5,UBXN2A,RIMS2,ZSCAN23,DAPK1,GIT2,ARMCX2,KLHL3,WDR20,DMD,NYAP1,NR1D2,DMTF1,DPYSL2,PDCD6IP,ECM2,DUSP9,KLHL5,FAM13A,PHF20L1,EGFR,MBNL2,EGR3,KCTD3,EIF5,USPL1,VPS13B,EPB41,EPB41L2,COQ7,DENND4A,ETV1,ADGRV1,ARMCX1,FCGR3A,OLFM1,FGF13,PRKAG2,SYNCRIP,ANKFY1,AFF2,DLL3,FYB1,ZNF44,GALNT15,DISC1,IGSF5,NEU3,SULT1C4,MMADHC,PPARGC1A,CRCP,TOX3,STARD3,ZNF638,LUZP2,TMEM121B,SPACA9,RNFT2,PADI2,HLF,HMGCL,AGBL5,HNF4G,HSF2,MSL1,RBPJ,SCIN,INPP5B,ITPKB,KCNH2,KIF5A,LMO2,HECTD2,NCOA7,MAP2,MARK3,MAT2A,MATN2,MBD1,MBNL1,LRP1B,MID1,AFF1,AFDN,XRRA1,MMP16,THYN1,HNRNPM,NFYA,NOVA1,NTRK2,PAX6,PIK3C2A,XRN1,GPSM2,PCDH18,STRN3,SCHIP1,EPB41L4B,SH3KBP1,CCDC144B,PPP3CA,PRKCB,MAPK9,PTCH1,PTN,PTPRB,SLC25A48,USP47,FAM66C,ZCWPW1,OXR1,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,ZMAT4,RFX3,PBRM1,ZFHX4,SETD5,CCDC102B,EPHA10,GLDN,TCP11L1,PTGR2,ATAT1,TRAPPC13,AP1AR,RMI1,SALL1,SATB1,CSRNP3,ATXN7,SCP2,PEAR1,SEC14L1,SCAF8,SHC4,FBXO11,FNDC3A,DZIP1,ABLIM3,PEX26,SLC6A11,SLC12A2,GKAP1,ANKRD36,SNRPN,USP33,TRERF1,SOX11,SP2,SP4,ERC1,SPTAN1,ZBTB43,RBM26,NKAIN2,ERBIN,ZSCAN29,NSFL1C,SYN2,PJA1,TAF9,TBCEL,FBXW11,ATMIN,TCEA1,NEU4,SATB2,ZEB1,TCF12,PCDHGA11,SYNE1,PUM2,FRYL,SIK3,FAM200B,ACTR6,FAM124A,RIMBP2,R3HDM1,TNS1,NPL,NR2C2,PPIL6,RUSC1,CA14,TSC1,RPL7L1,WIPF1,GUSBP1,ZNF711,MKRN3,LYPD6,TCEAL7,TMEM237,DPYSL5,INTS3,STOX2,ADAMTS9,SEMA3B,PDSS2,FAM13C,DOCK8,RTN4,ADAMTSL3,JMJD1C,NHSL1,ZDHHC20,IFT88,GAN" MicroRNA hsa-miR-17:mirSVR_highEffct hsa-miR-17:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.63E-108 2.59E-104 1.23E-106 1.14E-105 279 1602 "KCNH8,NCKAP5,FMNL2,SLC24A4,ABCD2,SEMA7A,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,CASK,LINC00173,STK33,RASL11B,SLC4A4,EIF4G3,ATP1B3,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,USP6,P2RX6,C1orf52,TIGD7,CFL2,MS4A7,B4GALT6,TAOK2,EPS15L1,TPP1,ABCG2,AKAP5,SLC4A8,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,DNM1L,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,EFCAB2,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,GABBR1,TRAF3IP2,B4GALNT1,ERAP1,SYT17,DISC1,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,CIT,AP4S1,RABL2A,IRAK3,HAS2,MSL1,METTL21A,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,SRSF12,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NACA,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,TMEM260,PTPN13,PTPRD,PTPRO,CEP97,TMEM255A,USP47,FAT4,OXR1,RASGRF2,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,ATXN2,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,PPP4R3A,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,RNF103,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-106a:mirSVR_highEffct hsa-miR-106a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.63E-108 2.59E-104 1.23E-106 1.14E-105 279 1602 "KCNH8,NCKAP5,FMNL2,SLC24A4,ABCD2,SEMA7A,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,CASK,LINC00173,STK33,RASL11B,SLC4A4,EIF4G3,ATP1B3,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,USP6,P2RX6,C1orf52,TIGD7,CFL2,MS4A7,B4GALT6,TAOK2,EPS15L1,TPP1,ABCG2,AKAP5,SLC4A8,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,DNM1L,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,EFCAB2,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,GABBR1,TRAF3IP2,B4GALNT1,ERAP1,SYT17,DISC1,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,CIT,AP4S1,RABL2A,IRAK3,HAS2,MSL1,METTL21A,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,SRSF12,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NACA,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE1B,ZDHHC8,CCSER2,JAKMIP1,PLIN1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,TMEM260,PTPN13,PTPRD,PTPRO,CEP97,TMEM255A,USP47,FAT4,OXR1,RASGRF2,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,ATXN2,LRFN5,SH3GL3,CHD9,FBXO11,FNDC3A,SYBU,WDR37,PPP4R3A,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,RNF103,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-489:mirSVR_lowEffct hsa-miR-489:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.91E-108 2.75E-104 1.30E-106 1.20E-105 301 1863 "CLK4,EMILIN3,XKR4,ADCY6,PTCHD1,FAHD2CP,ZNF608,INTS2,PCDH19,TXNDC16,ZNF578,ARHGAP20,PCDH10,BBOX1,GPRASP2,AMPD2,DPP10,KCNAB2,VAT1L,IGDCC4,SPTBN4,MARCH3,NUMB,CCAR2,TMEM108,ATP2A2,RIPK1,ADAM23,BCHE,BMP7,NAE1,SCAPER,MTMR3,MTMR2,CACNA1B,LURAP1,CAST,ISPD,MTMR7,P2RX6,CD86,LRBA,CDO1,TIGD7,ASIC3,PLEKHB1,CNOT8,NRXN3,SULT4A1,MAP4K4,CNR1,COL4A5,SUMF2,FAM171B,CLOCK,C2CD2,HAPLN1,CRY2,ANKRD44,CSF2RA,SEC24C,VCAN,CST3,PNPLA8,CTH,PUM1,RIMS2,DCAF4,USP6NL,HDAC9,MATR3,DGKB,DAPK1,IP6K1,AIF1L,SPATA2,ZNF804A,HEPH,MYEF2,TIAM2,KLHL3,LYPD1,SV2B,FAM107B,DLX1,CD99L2,NR1D2,CASP8AP2,E2F5,E2F6,PHC2,ANKRD46,HIPK3,TMTC1,FAM13A,KMT5B,AASS,STARD3NL,IGSF6,SPEG,MRPL37,MRPL10,MRVI1,ABCA8,SEC24B,FER,UBE2E3,MEX3B,SYNCRIP,NOP56,PDLIM5,ST6GALNAC3,MEGF11,C15orf41,GATM,GCNT2,MSTN,GLYR1,TOX3,ZNF638,HTATSF1,MAP7D2,GNAL,LNX1,ADGRA3,LPAR4,GRB10,GRIA2,SERP2,GSN,SOX21,ZHX1,MIER3,ELOVL5,NEGR1,SHISA6,IFI16,ZNF181,SOWAHA,FAM69A,ITGAM,SLC35G1,KCND2,STXBP5,CYP27C1,SFXN5,LIMS1,PACRG,GPR155,MARK3,MBP,MEIS1,SCAMP5,MMP16,MSR1,MYO5A,RTL5,NEFH,NELL2,NFE2L2,VWA2,DNHD1,NTRK3,PCDH9,PCSK1,PCSK5,PDPK1,GNG2,PFKFB2,PFKFB4,PKM,FAM216A,SLC25A23,PURG,SCHIP1,ING3,PRKCB,MAPK9,MASP1,PTK2,STK32A,ZIK1,PTPRG,ZNF793,FAT4,RASGRF1,RADX,RGS3,RGS4,RGS12,PRIMA1,TMLHE,RORB,PCMTD2,CCDC102B,SNX22,GLDN,ATAT1,KCNIP3,NCBP3,CCDC112,AP1AR,SEMA6D,SCP2,FNIP1,ZNF821,FOXRED1,MRAS,PPM1E,FERMT1,SHC4,CHD9,FNDC3A,FHOD3,ST6GAL1,NUBPL,ABLIM3,SLC2A5,WDR47,SLC6A8,SLC11A1,ELMO2,ATF7IP,CPEB4,RCOR3,IFT122,ANKRD36,KIF13A,USP33,TRERF1,BDP1,NMNAT2,SPP1,TEX2,NFASC,CLASP2,NXT2,PHLDB1,STX1A,KANK1,NECAB1,TMEM150C,SYP,SYT1,TACC1,PJA1,FBXW11,TCF4,TPCN2,TRIM2,PCDHB7,FRYL,SIK3,DICER1,SIRT1,AP4E1,ARL10,HEY1,ACTR6,TLR4,NR2E1,TNS1,TRO,STXBP4,ANKRD20A2,ZKSCAN5,WIPF1,CLIP2,XPO1,ZBTB14,ZNF24,TRIM9,NDRG4,MKRN3,LYPD6,POLR3H,FSTL5,DPYSL5,ZFAND5,SMARCAD1,DHX33,EMSY,CADM2,GDPD5,LINC02210,PRDM8,PRDM10,ADAMTS9,MDH1B,FAM47E,ST7,UBE3B,SMIM8,HNRNPA3,FBXO36,JMJD1C,TIGD6,RNF170,KLHDC1,RNF146,GAN" MicroRNA hsa-miR-1256:mirSVR_lowEffct hsa-miR-1256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.12E-108 3.98E-104 1.88E-106 1.73E-105 270 1502 "RALGAPA1,ASPHD1,KLHL32,PTCHD1,BEND6,SLC24A4,ZNF608,OSBPL1A,CC2D2A,C1QTNF3,ALCAM,ABCD2,ARHGAP20,BBOX1,UNC79,TRMT9B,AMPD2,OGT,SEMA7A,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,VAT1L,SHROOM2,IGDCC4,PDE8B,EIF4G3,ATP2A2,BACH1,BCHE,BCL7A,CFLAR,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,THSD7A,SLC25A14,VXN,SPAG9,RUNX1T1,CBLN1,P2RX6,ENTPD6,DGKI,MAGI1,TIGD7,COPB2,FAM189A2,HECTD1,CNTFR,CNTN1,ARMC8,FAM149A,SLC4A8,SMARCAL1,CLOCK,AKAP12,GDA,SEC24C,PDE4DIP,PLCXD3,GREB1,HDAC4,TM9SF4,TBC1D5,TMEM170A,PABPC5,MYEF2,SPOCK3,WDR20,RAB39B,DMD,NYAP1,DYNC1I1,CDON,RCAN1,MAMLD1,DNAJB6,AASDH,EBF1,EDNRB,FCF1,CNNM1,SEMA3D,EGR3,KCTD3,EIF4G2,PCOLCE2,EIF1,EPB41L2,RCAN2,LRRC17,SRRM1,ERBB2,ZNF549,TLR7,EYA1,ACSL4,TAOK3,SCML2,CHST15,ZSCAN30,GORAB,FGF1,FGFR1,SUCO,HPCAL4,SYNCRIP,FLT1,ANKFY1,C2orf88,ZBED3,DISC1,LRRC37A6P,SULT1C4,MSTN,FREM1,GGTA1P,PPARGC1A,MSL3,HTATSF1,LUZP2,DCLK2,RAB40B,WDFY3-AS2,CNTRL,GRIA2,ADAMTS13,GRM2,PRDM5,ZBTB49,BVES,AP4S1,HAS2,UBE2QL1,ATXN2L,VSIG4,HNMT,SHISA6,SMAP1,EID2B,TJAP1,IL6ST,INSM1,JAK2,KCNK3,IPO5,STXBP5,STMN1,PAXBP1,LMO2,ZFYVE27,MAT2A,MBNL1,MMP16,RTL5,NEXMIF,P2RY13,ZC3H12B,NEK1,NF1,CNOT4,DNHD1,SMIM11A,GLIPR1L2,ETFRF1,PCSK1,PRTG,PDE4D,ENPP2,SLC10A4,GNG2,SEMA5B,SLC25A23,PCDH18,PNMA3,MAPKAP1,STRN3,MBOAT7,PPP3CA,PKIA,PRKCB,EPDR1,PIGG,CNTLN,PTPN13,PTPRN2,NKAIN1,PID1,SLC25A48,HKR1,KHDRBS2,ZDHHC14,TRIM68,FIGN,RGS12,SLC25A36,RIC8B,TMLHE,MEG3,RXRA,SEMA6D,HES6,TRA2B,PPM1E,FBXO11,FHOD3,NLGN1,SLA,PREX2,PPP4R3A,EPN2,SLC14A1,BTBD7,ANKRD36,MBD5,KIF13A,KDM4B,PDZD2,GLT8D1,HECW1,KDM4C,TEX2,LHPP,PBLD,ITPRID2,STAU1,RGL1,DIP2A,SULF2,PRRC2C,TMEM150C,PDLIM2,AGTPBP1,KLHL4,SATB2,TCF12,PCDHB4,FRYL,CYB561A3,RNF216P1,ZFPM2,MTMR14,R3HDM1,CSMD1,TNS1,SLC35A4,OSBP2,FLRT2,VLDLR,WIPF1,CLDND1,ZBTB14,ZNF23,ZNF154,TMEM237,FSTL5,SMARCAD1,MEIS3,INTS3,STOX2,TMEM178A,GAL3ST3,ST7,HNRNPA3,CASC15,JMJD1C,LAS1L" MicroRNA hsa-miR-219-2-3p:mirSVR_lowEffct hsa-miR-219-2-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.95E-108 4.45E-104 2.09E-106 1.92E-105 298 1830 "FMNL2,CCDC85A,TMCC3,KIAA1211,PTCHD1,AP2A2,ZNF608,HECW2,OSBPL1A,OSBPL8,SPARCL1,SEMA6A,ALCAM,UNC79,FAM135A,ZNF687,DPP10,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,TNRC6C,LGR5,CDC14B,SEMA4G,SLC4A4,EIF4G3,N4BP2L1,BACH1,ADGRB3,LINC00847,BBS2,MPDZ,SEC11C,BCL7A,PROM1,KSR1,GYG2,SGCE,WASF1,CACNA1A,VXN,CARS,ISPD,PRC1,MTMR7,SLC16A4,P2RX6,ZBED1,CDH2,DCLK1,LRRFIP1,CLGN,CHGB,TPP1,ABCG2,CNTN1,ARMC8,SEC31B,CDC42BPB,C2CD2,LRIG1,OSBPL3,PLXNA4,KIAA0040,RUBCN,USP6NL,ARHGAP32,TBC1D5,DAPK1,SPOCK2,SPATA2,YTHDC1,ZBTB24,DDX46,SGSM2,WDR20,RAB39B,DMD,USP3,DMTF1,DNAJB6,DNM1L,GOLT1B,FCF1,FSD1L,MRO,MBNL2,AASS,EIF5,TENM1,PLEKHA1,STARD3NL,USPL1,EPHB1,RABEPK,STX2,EYA1,FAM198B,CEP78,PPP1R1B,GORAB,POLK,SUCO,PCYOX1,AFF2,AKAP3,NBEA,APOPT1,STAMBP,ATP2C1,ST6GALNAC3,AP4B1,TVP23A,OGA,GALNT15,GHDC,IQGAP2,C15orf41,DISC1,LRRC37A6P,TUBGCP4,ARFIP1,GDF9,CYP46A1,ADAM28,FREM1,NTNG2,TCERG1,KDM2B,LUZP2,GPD2,GPR37,TMEM121B,GRIA2,ADAMTS13,GRIN2C,PRDM5,SOX21,ADAMTS6,MAP4K5,MIER3,ELOVL5,HMGCR,LRRC75A,SHISA6,IRF8,IGF1,LRRCC1,SLC6A17,INSM1,SLC35G1,KCND2,KCNJ16,KPNA5,SFXN5,PAXBP1,LMO2,PACRG,MAT2A,AQP11,MBNL1,MEF2C,KITLG,MMP16,SAMD5,ADAM22,N6AMT1,MYO5A,MYO6,ZC3H12B,NFE2L2,ALDH1L2,DNHD1,SLC11A2,OXTR,P2RX7,CNTN3,PCDH9,PCSK5,PDCD2,GPR85,GNG2,PIK3R1,RETREG1,FAM216A,PDZRN4,PMP22,ING3,PPP2R2B,PPP2R5E,PPP3CA,SAMD9,VPS13C,QRICH1,CNTLN,PTN,STK32A,EML5,PTPRN2,ZNF615,ZNF844,PID1,SH3TC2,OXR1,RBBP8,HKR1,MSANTD2,FIGN,RFX2,EXD2,ROBO2,RORB,CCDC102B,RPL15,GLDN,RTN1,RYR3,CCDC112,RMI1,SATB1,LRFN5,MRAS,SUPT20H,HSPA4L,KIF21A,CHD9,ST6GAL1,PPP4R3A,SLC8A1,BTBD7,IFT122,LIMCH1,MBD5,KIF13A,CABCOCO1,DOP1A,DOK5,ZNF423,CDK19,TSPYL2,RBM26,NFASC,ZSCAN29,NEK4,SEPT8,SEPT3,ARHGEF9,VPS13A,PLCB1,CAMTA1,DNMBP,ADGRL3,TBCEL,KLHL4,MGRN1,WSCD1,CUX2,DOCK9,GPRIN3,ZFPM2,AKTIP,TK2,LRRC8A,R3HDM1,TPM1,TSN,TTTY15,SGK3,VSNL1,WIPF1,P2RY12,WNT7A,WRN,GUSBP1,XPO1,XRCC4,SLC47A2,PCDH20,ZNF24,ZNF28,TRIM9,AGMO,LYPD6,ZNF142,ANKS1B,MFF,PRTFDC1,TRIM16L,WNK3,WNK2,FAM13C,FZD3,JMJD1C,RNF170,KLHDC1,NETO1,ST8SIA2,SENP7" MicroRNA hsa-miR-22:mirSVR_lowEffct hsa-miR-22:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.47E-108 5.30E-104 2.48E-106 2.28E-105 283 1653 "CLK4,EMILIN3,ADCY6,ADD1,BRAP,ADORA1,ADRA1D,ADRA1B,SLC24A4,AP2A2,INTS2,PCDH19,AK2,SPARCL1,ALCAM,SYT13,DOC2A,BIN1,DPP10,ANK2,PKP4,BCAS1,TNRC6C,LGR5,SHROOM2,CDK10,ARNTL,CHRD,NCOA1,NUMB,SLC2A11,N4BP2L1,ADGRB3,ZNF599,CFLAR,KSR1,ST3GAL5,CASTOR3,MTMR2,GYG2,CALB2,CABP7,KALRN,CBR1,P2RX6,ARHGEF1,DGKI,LRRFIP1,LARGE1,SRSF11,EPS15L1,RAB28,STOML1,HECTD1,RAB26,HOMER3,AKAP6,SLC4A8,RTTN,ENTPD4,CRHBP,GDA,SNCAIP,CSNK1E,GALNT9,RIMS4,KIAA0040,PHF14,CTH,GREB1,ZFYVE16,KIF26A,IST1,B3GAT3,SPOCK3,TMCC2,EXOG,DNM1,SLC29A4,DPH1,DRP2,DTNA,GOLT1B,AASDH,PHC2,SEMA3D,TMEM132E,ASB3,TNK2,MRNIP,ELN,TMEM35A,EMX2,TUBD1,EPB41,MFSD10,MRVI1,CLVS1,CHST15,FER,FGFR1,SUCO,SCARA3,AGAP3,FLT1,PSD2,NOP56,FOLH1,WDR83,ATP2C1,CGREF1,STAU2,DOT1L,MEGF11,GALNT15,MTHFD2,DISC1,SEPT9,LRRC37A6P,TUBA8,GGT7,CRCP,COPS8,MSL3,POLL,DCLK2,GPT2,GPD1,GPD2,CCDC184,DIDO1,ADAMTS13,CIT,KAT7,ZBTB49,PSIP1,SLC2A6,ATOH8,PADI2,NEGR1,IGF1,TJAP1,IL6ST,FAM69A,ITPKA,LIG4,LSS,MBNL1,MEIS1,KCTD6,AFDN,MOV10,SAMD5,COMMD5,ZNF862,NFYA,VWA2,CNOT4,SMIM11A,NTRK2,PAX6,PCDH9,ENPP2,GNG2,XRN1,LRP12,EPB41L4B,FA2H,PRKCB,MAPK10,HYDIN,APTX,SNRK,CNTLN,MTMR10,ELOVL2,PTN,PTPRE,PTPRN,PEX2,CCDC40,TRIM68,DPF2,RET,RGS12,RNH1,LGI2,TMLHE,KLHDC8A,ALG9,ARMC5,CCDC25,SNX22,RPL15,ZC3H14,FAM161B,HUNK,NCBP3,TRAPPC13,FAM192A,MAPK12,SEMA6D,ATXN2,ATXN7,PRCD,SCP2,SEC14L1,ZNF821,KIF21A,FAM102A,FHOD3,FAM81A,BTBD3,DHX30,KANSL3,SLC6A8,ARHGEF40,SLC9A5,BTBD7,EPC1,MYH15,LIMCH1,USP33,SOX3,BDP1,ZSWIM8,MYCBP2,KDM4C,PEG10,ZNF423,CAMTA2,MESP1,ELOVL4,SYN2,C12orf76,ANKRD12,MLST8,MCF2L,TRIM2,RPGRIP1L,DOCK9,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,DNAH7,ZFPM2,GALNT17,TIAM1,RELL2,TK2,ZNF346,PPIL6,KCNE5,CLHC1,SLC35A4,VLDLR,CLIP2,NPDC1,ZNF19,ZNF24,PCBP1-AS1,SMARCAD1,INTS3,SLC30A4,CADM2,PRTFDC1,STOX2,SEMA3B,FAM47E,EPM2A,RGS7BP,DOCK8,MARCH8,UBE3B,KAT6A,FRMD6,SENP7" MicroRNA hsa-miR-155:mirSVR_highEffct hsa-miR-155:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.19E-107 6.64E-104 3.09E-106 2.84E-105 265 1449 "CLK4,FMNL2,AXIN2,PWWP2A,MTUS1,HECW2,TBC1D14,SPOP,ALCAM,ABCD2,ARHGAP20,FAM135A,LCORL,MAP4K3,APAF1,TNRC6C,USP37,IGDCC4,NUMB,SLC2A11,BACH1,KSR1,DST,SCAPER,CASTOR3,KALRN,PTBP2,CAST,CD38,CCPG1,UBE2L6,RCBTB2,SOCS6,CHN2,B4GALT6,CLCN3,QKI,CNTN1,SLC4A8,ENTPD4,ANKRD44,CLIP3,CSF1R,SIPA1L1,SOCS5,PLXNA4,PHF14,PUM1,DCAF4,BOC,TBC1D5,DAPK1,MYEF2,GSDME,GRIN3A,RAB39B,DYNC1I1,NR1D2,DMTF1,DTNA,GOLT1B,E2F5,AASDH,EDNRB,KLHL5,FAM13A,PHF20L1,EGFR,MBNL2,KCTD3,PLEKHA1,C3orf18,IGSF6,CEP85L,EYA1,FAM198B,FGF14,FHL1,ANKFY1,SMC2,UFM1,PDLIM5,SARAF,MEGF10,GALC,C15orf41,DISC1,KIAA1841,GATM,SESN1,COPS8,DBF4,MSL3,ZNF638,DCLK2,GRM8,KAT7,PSIP1,GUCY1B1,MIER3,NEGR1,SHISA6,IRF8,SCIN,FAM69A,KHK,STXBP5,L1CAM,LAMP2,LIG4,PAXBP1,HECTD2,NCOA7,SMAD1,MARK1,MBNL1,TM6SF1,LRP1B,MEIS1,MITF,AFDN,MMP16,ZNF680,ZNF92,ZC3H12B,NEFH,NEK1,NOVA1,SLC11A2,IGSF11,GLIPR1L2,CNTN3,PCDH9,PRTG,PDE3A,PDE4D,GPR85,PIK3C2A,FAM216A,STRN3,EPB41L4B,DRAM2,MINDY2,PRKACB,CEP41,PKIA,SLC26A11,DIRAS2,WDR25,CNTLN,ELOVL2,PTN,TMEM260,PTPRB,PTPRD,PTPRG,PTPRN2,USP47,RAD51D,RBBP6,ZMAT4,REV3L,PBRM1,CCDC82,DCUN1D2,CARF,CYB561D1,ROBO2,RPE,NEK11,ABCA11P,TRAPPC13,FAM192A,S100B,SATB1,SCN7A,KIF21A,CHD9,FBXO11,NLGN1,SLA,BTBD3,SEPHS1,SLC12A2,BTBD7,SMARCA4,ANKRD36,LIMCH1,SNAP25,SNRPN,FAM126B,SOX11,HECW1,KDM4C,ZC3H13,RBM26,SPART,NKAIN2,CEP68,RGL1,SYNE2,VPS13A,NUDT10,PLCB1,SYPL1,C12orf76,TACC1,CAMTA1,FAM208A,ADGRL3,TBCEL,KLHL4,TCF12,SYNE1,DOCK9,PCDHB10,PCDHB9,SLC19A3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,AKTIP,ASXL3,FAM124A,CSMD1,TPM1,RGMB,TRPS1,ZKSCAN5,CLHC1,SGK3,UBE2H,PLEKHH2,CCDC14,TBC1D15,LAT2,ZNF781,RICTOR,ZNF28,TRIM9,CELF4,ZBTB38,FSTL5,PRTFDC1,RNF103,VPS35L,NAV3,FAM47E,PDSS2,EPM2A,RGS7BP,AMN1,KAT6A,HNRNPA3,CASC15,ADAMTSL3,FXR1,FRMD6,NETO1" MicroRNA hsa-miR-382:mirSVR_lowEffct hsa-miR-382:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-107 7.82E-104 3.62E-106 3.34E-105 290 1738 "ABR,EMILIN3,NCKAP5,XKR4,NDRG2,CCDC85A,ESYT2,PTCHD1,FAHD2CP,DPY19L2P4,KLHL13,CASKIN1,OSBPL1A,WDR35,ADGRF5,ABCD2,PCDH10,BBOX1,SYT13,CDC42BPA,LRCH2,CCDC146,APC,EPB41L5,MAGEE2,LGR5,CADPS,CDK13,NUMB,ATP1B3,DOCK11,ADAM15,RGS9,BCL7A,SCAPER,CA12,CALB1,CALB2,CABP7,CALM1,KALRN,PTBP2,MTMR7,P2RX6,DGKI,AP4M1,B4GALT6,LHX2,NRXN3,TPP1,FBXO7,CNR1,CNTN1,ARMC8,AKAP5,ABI3BP,RCHY1,RTTN,TOGARAM2,MYRIP,ZNF521,ZFP28,C2CD2,CRMP1,HAPLN1,ANKRD44,GDA,SEC24C,CST3,FAM169A,SLITRK5,DZIP3,UBXN2A,RIMS2,USP6NL,DOCK4,MATR3,KIAA0586,DGKB,DGKG,BRINP1,AIF1L,DGCR5,MYEF2,KIAA0753,DTNA,DNAJB6,EDN1,SEMA3D,KLHL5,TMTC1,FAM13A,PAN3,USPL1,TUBD1,GPHN,ERBB4,ETV1,DNAJC27,EZH1,F5,FAM198B,CEP78,FGF13,EVL,HVCN1,PDLIM5,MEGF11,MEGF10,TMEM8B,SRRM4,SRCAP,ARFIP1,ADAM28,GHR,DHRS4,BRD8,COPS8,GLUL,LNX1,TDRKH,GPR37,TPPP,C1QL4,KAT7,PSIP1,ADAMTS6,RASSF8,FRMD3,HNMT,C9orf129,AGFG1,SMAP1,FAM95B1,C2orf72,GAREM2,NIM1K,KNDC1,IL6ST,IL12A,INPP5B,SLC35G1,GPR62,KCNN3,STMN1,PAXBP1,HECTD2,GPR155,MBD1,CHIC1,MEF2C,PPM1L,MITF,AFDN,ADAM22,TAGLN3,NACA,CCDC13,NF1,NFE2L2,OPA1,PAX6,PCDH8,PRTG,PDE1C,PDE4D,OLA1,ZNF655,KCTD15,GPSM2,MTRF1L,PURG,PMP22,PPM1B,CEP41,MAPK4,BCAS3,QRICH1,PIGG,EML5,PTPRG,TTC13,TUG1,TMEM255A,ZNF793,SH3TC2,FAM184A,RASGRF1,KHDRBS2,MSANTD2,SLC25A36,LGI2,ZNF532,EXD2,RORB,RPE,NEK11,ARMH4,FBXW7,GLDN,HSD11B1L,ATAT1,RTN1,ZNF354C,DGLUCY,SEMA6D,TNFRSF19,ZFP2,MRAS,TRA2B,SCAF8,SH3GL3,FERMT1,CPEB3,FBXO11,NLGN1,DZIP1,PPP4R3A,SEPHS1,SIRT2,CCDC88A,BTBD7,ANKRD36,KIF13A,LMBRD1,TMCC1,PDZRN3,USP33,SP2,TEX2,TSPYL2,LHPP,CLASP2,ZC4H2,LARP4,ERBIN,ELOVL4,KANK1,SULF2,SEPT3,NECAB1,ARHGEF9,ANKRD28,SYT5,MTCL1,PDLIM2,ADGRL3,SMG6,KLHL4,TCF4,DMXL2,CUX2,ZEB1,TRIM2,RPGRIP1L,USP22,FRYL,SIRT1,AP4E1,SLC44A1,R3HDM1,NPL,AMACR,TSC1,SSBP2,TTTY15,TTC3,VLDLR,WNT7A,RICTOR,PCDH20,ZNF17,TMEM237,ZSCAN26,FTSJ1,RNF103,HPS4,GAL3ST3,KCNAB1,TRIM16L,MPPE1,EPM2A,DNAH10,FZD3,DOCK8,HNRNPA3,FBXO36,TTC7A,NETO1,RNF146" MicroRNA hsa-let-7d:mirSVR_lowEffct hsa-let-7d:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-107 8.10E-104 3.73E-106 3.44E-105 293 1774 "GALNT16,GALNT13,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,OSBPL1A,ARHGAP20,FAM135A,BEGAIN,LCORL,PHF12,AQP6,CDC14B,SEMA4G,CDK13,CHRD,NCOA1,CHID1,ATP2A2,SLC2A11,ADAM15,MPDZ,CACNB4,CALM1,PTBP2,CAST,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,LARGE1,TIGD7,CLGN,NUMBL,ASIC3,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CREM,CRY2,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,MYEF2,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DMTF1,DPH1,ARRDC4,ECM2,DNAJB6,SNX29,EDNRB,ANKRD46,YAF2,EBI3,EGR3,RASA4,AASS,GOLGA7,CERCAM,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,CORO2B,DLC1,CHST15,GTF2IRD2,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,SIGLEC8,DISC1,GHR,PPARGC1A,LYVE1,TOX3,GLUL,KDM2B,POLL,STON1,TMEM121B,GRIA2,SPACA9,RNF165,FICD,AP4S1,LINGO1,HAS2,HLF,HMGCL,HMGCR,LRRC75A,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RY1,CNTN3,PAX6,PCDH9,PCSK1,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PLCB2,TRHDE,SCHIP1,RANBP3L,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,PTPRG,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,TRIM68,KCTD17,DCUN1D2,KLHDC8A,CCDC102B,EPHA10,KIAA0895L,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,FOXRED1,HSPA4L,SH3BP2,CPEB3,WDR37,BTBD3,EPN2,FAM214B,ATF7IP,CPEB4,MAST1,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,DDN,NFASC,POGZ,ITPRID2,SSTR2,SLC37A2,PDLIM2,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,HIF3A,RNF216P1,DICER1-AS1,AP4E1,ARL10,TIAM1,NPL,WBP2,CHST5,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,SLC35A4,ZNF709,WIPF1,ZNF781,PCDH20,ZNF28,MEIS3,EVI5,FIP1L1,TRIM16L,KAT6A,CASC15,TIGD6,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-3169:mirSVR_lowEffct hsa-miR-3169:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-107 8.91E-104 4.09E-106 3.76E-105 289 1727 "RALGAPA1,XKR4,TMCC3,GALNT13,PWWP2A,ZNF608,INTS2,KIAA1324,AMPD2,ZFAT,EP400,LCORL,MAP4K3,APLP1,VAT1L,USP37,LGR5,PPP4R4,TMEFF1,PCDHGB4,CHRD,SLC4A4,MIR9-3HG,NRP2,KSR1,BMP7,SYNJ2,MYRF,CFAP410,CA12,CALB2,CAMK2G,ARHGEF25,LDB2,ENTPD6,CDC25B,CDO1,CLGN,NUMBL,RCBTB2,ASIC3,PLEKHB1,FBXO7,LY86,CNR1,ARMC8,LETMD1,RCHY1,COX4I1,ZFP28,NECTIN3,ANKRD44,TRIM69,LRIG1,SUSD5,PNPLA8,DCAF4,GPRASP1,ARHGAP32,MAML1,IP6K1,ZBTB24,KLHL3,LYPD1,SV2B,SEC16A,DLX1,DNM1,USP3,DYNC1I1,NR1D2,CDON,DPH1,ACOT8,TOM1,KRBA2,GOLT1B,FSD1L,EGFR,RGS17,TMEM35A,PAN3,EIF1,EMX2,RCAN2,NCALD,RASL12,SIRPB1,F8,SCML2,CORO2B,DLC1,FCGR1A,CEP78,CHST15,FCGRT,ZSCAN30,OLFM1,FGF13,FGF14,EVL,SEMA4D,ATP13A4,FLT1,NOP56,SYT3,HVCN1,RASL10A,HHIPL1,CHL1,GABRG2,B4GALNT1,RAPGEF6,IP6K3,DISC1,ALDH1L1,PCDH17,TTBK1,GNG4,GPR12,ADAMTS13,GRM2,ZBTB49,MUM1,IRAK3,HMGCL,NEGR1,LRRC75A,SHISA6,CELF5,IL6ST,KCNB1,CREG2,LIMS1,PIK3AP1,MAP2,MBP,ADAM11,KCTD6,XRRA1,ZNF680,MSR1,PTOV1,ZNF862,TCEAL5,CCDC13,NFE2L2,ALDH1L2,NOVA1,DNHD1,OPA1,P2RX7,DPY19L2P2,PCDHGC3,PCSK5,ENPP2,PFKFB2,PFKFB3,PIK3R1,GPSM2,PLTP,PRIMPOL,PSAT1,PRKAB2,GRAMD1C,HYDIN,APTX,WDR25,PIGG,PTPRB,PTPRE,CASTOR1,PTPRG,PEX2,ZSCAN2,QDPR,NWD1,RAP1GDS1,ZNF493,RASGRF1,RASGRF2,RADX,KHDRBS2,ZDHHC14,ZMAT4,PRRT2,RFX2,UBR7,KIF7,RIC8B,ZFHX4,LGI2,C12orf49,KLHDC8A,ALG9,KIRREL1,BAALC,SPIN3,ZC3H14,ATP8B4,GLDN,ADAL,STK32B,ABCA11P,ST6GALNAC6,ZNF354C,FAM192A,ATXN2,SCN8A,PRCD,SUPT20H,FAM102A,MYO18A,WDR37,SLC2A5,PEX26,FAM214B,ELMO2,ABTB1,TTC17,IFT122,LIMCH1,SNCA,CABCOCO1,SNRPN,TSNAXIP1,UNC5B,RBM26,NKAIN2,ST5,STAC2,SULF2,SEPT3,SYNE2,SYN1,MMS19,TACR1,ADGRL3,TBCEL,TBL1X,ATMIN,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZNF106,CDH22,TIAM1,TMPO,TNS1,CHST5,SYNPO2,PDSS1,PPIL6,TUBB1,OSBP2,ZNF709,ATP6V0E2,NDRG4,CRB2,MKRN3,ZNF138,GDPD5,NAV3,FZD3,ST7,UBE3B,FBXO36,TRAM2-AS1,TTC7A,IFT88,AP3B2,SOCS4" MicroRNA hsa-miR-605:mirSVR_lowEffct hsa-miR-605:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-107 9.10E-104 4.16E-106 3.83E-105 307 1945 "RALGAPA1,ACADM,GALNT16,TMCC3,ADRA1B,DPY19L2P4,MTUS1,CASKIN1,AGT,HACE1,NME5,HFM1,TAOK1,SPOP,LCORL,PHF12,APBB2,EPB41L5,VAT1L,TNRC6C,USP37,LGR5,CDK13,CCAR2,ATP1A1,ATP1B3,ATP2B2,DPY19L3,MYOM1,AZGP1,ADGRB3,MPDZ,BID,KSR1,CA8,CACNA1A,CACNB4,ZNF501,CLDN10,USP6,CD38,ARHGEF2,SEPT7,CDO1,DLGAP1,CFL2,MS4A7,B4GALT6,EPS15L1,PCYT1B,AKAP6,AKAP5,SLC4A8,TBPL1,ZFP28,IGDCC3,SH2B1,AATK,LRIG1,IPCEF1,SIPA1L1,VCAN,PDE4DIP,CST3,FAM169A,SLITRK5,PLCXD3,DCAF4,RUBCN,FAM131B,CCDC144A,BOC,LIN54,KIAA0586,MAML1,DGKB,DAPK1,SCRN1,PITPNC1,YTHDC1,MFAP3L,TMEM130,ALKBH8,POM121,PLPPR4,SNAP91,SPOCK3,SGSM2,TMCC2,WDR20,CHRDL1,EXOG,USP3,DYNC1I1,DPYSL2,SLC25A18,ABCC5,DNM1L,E2F6,AASDH,HIPK3,SEMA3D,KLHL5,TMTC1,FSD1L,OPTN,FAM13A,KMT5B,EGR3,RASA4,ELN,EPB41,ETV1,EYA1,NSRP1,FAM198B,ACSL4,PPP1R1B,ZNF589,FGFR1,POLK,HPCAL4,IP6K2,SYNCRIP,RGPD5,FOXO3,FLT1,C2orf88,FAM49B,ATP2C1,ERGIC3,SARAF,ZMAT1,B4GALNT1,ZNF274,C15orf41,INPP5K,LRRC37A6P,GHR,PPARGC1A,DHRS4,GLYR1,RAB30,ZNF638,GNAL,FERMT2,ADGRA3,PRUNE2,CCDC184,AP4S1,RNFT2,ATOH8,HAS2,HLF,GABARAPL2,SOWAHA,LRRC25,ZIC5,LRRCC1,SCIN,IL6ST,INPP5B,GPR62,KIF5A,LAMP2,LIG4,MATN2,SCAMP5,PPM1L,MN1,MYO7A,MYO9A,NEXMIF,ZNF862,ZC3H12B,PCDH9,PDE4A,PFKFB2,SERPINI1,NALCN,PIK3C2A,PIK3R1,PLTP,PDZRN4,ING3,EPB41L4B,MINDY2,PPM1B,KANSL1,RANBP3L,PRKAB2,EPDR1,SAMD9,WDR25,CNTLN,MTMR10,PTPRG,PTPRO,ZSCAN2,TUG1,SLC25A48,FAM66C,OXR1,BEND5,RBBP8,MSANTD2,RDX,ZMAT4,RFX3,ZFHX4,ROBO2,BAALC,SGSM1,TCP11L1,RPS6KA2,MAP6D1,ST6GALNAC6,ATAT1,ZNF331,TRAPPC13,SAFB,SCN2B,SCP2,GALNT10,FOXRED1,MRAS,RASA3,SH3GL3,FERMT1,CHD9,FHOD3,NLGN1,ABLIM3,SLA,SLC2A5,PPP4R3A,WDR47,PKNOX2,SLC9A5,TRIM67,NAPB,ELMO2,TET1,GKAP1,LIMCH1,FAIM2,LMBRD1,TMCC1,FAM126B,TRERF1,BDP1,FNBP1,SP4,RBM26,SPART,LMO3,ITPRID2,SSTR2,NKAIN2,SS18,RGL1,ZC3H4,ARHGEF9,SYN2,SYPL1,TACC1,CAMTA1,AGTPBP1,TBCEL,TBL1X,MGRN1,ATMIN,TCF4,SATB2,ZEB1,RPGRIP1L,PCDHB9,SLC19A3,OBSL1,CCDC173,ZNF106,TK2,FAM124A,STXBP4,PPIL6,TTTY15,RPL7L1,UBE2H,ZIC2,ZNF28,ZNF70,LYPD6,TMEM237,FSTL5,LAMP5,SLC38A1,ADAMTS9,FAM47E,PARP11,EPM2A,RTN4,UBE3B,FBXO36,FRMD6,SOCS4,LAS1L,JPH3" MicroRNA hsa-miR-134:mirSVR_lowEffct hsa-miR-134:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-107 9.24E-104 4.20E-106 3.87E-105 277 1587 "ASIC1,KLHL32,RNF157,ADD1,ADORA2A,KIAA1211,OLMALINC,ZNF608,INTS2,TXNDC16,ZNF578,ALCAM,PCDH10,BBOX1,AMPD2,DPP10,MAP4K3,MYH7B,KCNAB2,BCAS1,TNRC6C,SHROOM2,CASK,ARRB1,LINC00173,SLC4A4,STX16,TTLL9,ADAM15,SEC11C,RGS11,ARHGEF7,BTK,SCAPER,JAZF1,CFAP410,CACNB4,CALM1,SPAG9,ENTPD6,C1orf52,SEPT7,LRRFIP1,DLGAP1,UBE2L6,FOXN3,B4GALT6,ABCG2,SRP14-AS1,CNR1,AKAP6,COL4A5,SLC4A8,COX4I1,SMARCAL1,ZNF385A,ABCG1,CSF1R,CSNK1E,CSNK1G3,VCAN,SOCS5,FAM169A,ARHGEF4,RIMS2,GPSM1,RUBCN,KIAA0408,DOCK4,ARHGAP32,INTS1,SCRN1,TIAM2,MFAP3L,KIAA0753,CHRDL1,DLX1,GRIN3A,DMD,DNM1,HS3ST2,SLC29A4,CDON,CPEB2,DTNA,ABCC5,KRBA2,EDN3,ANKRD46,RASGRP1,PHF20L1,KMT5B,EGR3,PLEKHA1,PAN3,ZNF549,MRPL10,ZNF589,FGF1,FLT1,SLC37A3,NELFCD,NBEA,TMEM107,HVCN1,UFM1,CAMKK2,CELF1,STAU2,AP4B1,OGA,ZMAT1,ZNF559,SRRM4,GATM,GCNT2,NFU1,PPARGC1A,TTBK1,CRCP,RNPS1,HPGDS,GLUL,ZNF782,ADGRA3,GPD2,GPER1,ATP2B1-AS1,GRIA2,FAM19A2,KAT7,IRAK3,RASSF8,ARHGAP36,ACOT7,GABARAPL2,HMGCL,NEGR1,IDH3A,TJAP1,IL6ST,KLHL23,KCNJ16,CREG2,STXBP5,LIMS1,PAXBP1,NCOA7,CHIC1,MEIS2,MGAT3,PPM1L,MKLN1,MYCN,MYO5A,NF1,NUCB2,TBC1D25,OCRL,GPR137C,DPY19L2P2,PCDH9,PCSK1,PDE4B,PDE4D,PDPK1,PLCL1,SLC25A23,PRIMPOL,RANBP3L,BCAS3,MTMR10,TMEM260,NKAIN1,QDPR,MARCH1,PID1,CEP97,SLC25A48,CCDC40,FAM66C,ENOX1,OXR1,RASGRF1,RDX,ZMAT4,REV3L,GTDC1,RGS4,EXD2,ALG9,KIRREL1,SNX22,EPHA10,FBXW7,SPIN3,ZC3H14,ZNF671,MCMBP,GLDN,MAP6D1,NCBP3,ZNF331,FNIP1,PPM1E,CPEB3,WDR37,CCDC88A,SLC12A4,CPEB4,MAST1,MYH15,FAIM2,DOP1A,PDZD2,DOK5,UHRF1BP1L,KDM4C,UNC5B,SPART,LHPP,ATP10B,TROVE2,NKAIN2,ZSCAN29,SYN2,COBL,MTCL1,PJA1,ADGRL3,SIN3B,RPGRIP1L,CLASP1,SZT2,SYNE1,PHF24,PCDHB7,PUM2,TNS2,FRYL,CCDC173,PMS2CL,AP4E1,ZNF106,MTMR14,FAM124A,PIK3R5,ELP5,TRIO,TRO,STXBP4,DCBLD1,PLEKHH2,CCDC136,LAT2,KLC2,CLDND1,KCNK12,ZNF45,LYPD6,TMEM237,POLR3H,EML6,SMARCAD1,UPF3A,ZXDA,RNF103,FIP1L1,EPM2A,DOCK8,ST7,HNRNPA3,FAM219B,RNF170,SNX14,FAM181A,SENP7" MicroRNA hsa-miR-137:mirSVR_lowEffct hsa-miR-137:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-107 9.72E-104 4.40E-106 4.05E-105 280 1622 "SYN3,AS3MT,TMEM132B,ELFN2,CCDC85A,RNF157,BRAP,PWWP2A,KIAA1211,RNF150,MTA3,SLC24A4,HECW2,KCTD16,OSBPL1A,OSBPL8,CC2D2A,HFM1,ARHGAP20,FAM135A,KCNAB2,MAGEE2,CDK13,NCOA1,ATP2A2,N4BP2L1,ATP6V0A1,BACH1,BBS2,MPDZ,MIR9-3HG,BID,SYNJ1,FUBP1,SGCE,IL33,CCNH,C1orf52,L3MBTL4,CLGN,SOCS6,B4GALT6,TPP1,FHL5,PCYT1B,AKAP6,LETMD1,RTTN,TOGARAM2,ZNF521,PREPL,C2CD2,CREM,CRHBP,SEC24C,ARHGEF10,OSBPL3,RIMS4,PDE4DIP,CNTNAP2,ERC2,CTH,PPP6R2,ARHGAP32,DCAF8,MATR3,DGKG,TMEM170A,DBN1,YTHDC1,JAKMIP2,MFAP3L,POM121,SNAP91,SPOCK3,WDR20,DYNC1I1,DMTF1,SLC12A6,WDPCP,EDNRA,TMTC1,FAM13A,MRO,KMT5B,EGR3,GOLGA7,EIF4G2,PCOLCE2,C8orf37,USPL1,EIF1,EMX2,COQ7,GPHN,MRPL37,ABCA8,SH3YL1,TAOK3,DLC1,FKTN,GORAB,MED12L,FGF1,FGF11,PRKAG2,POLK,IP6K2,SEMA4D,SMC2,FAM49B,NSG1,STAU2,FYN,GABRG2,ZNF234,MTHFD2,CPLX1,GATM,SESN1,AHDC1,GFRA2,COPS8,SPIN1,TOX3,PRUNE2,GPR37,PCLO,CACFD1,GRM8,LINC01089,PSIP1,GUCY1A1,FRMD3,MIER3,ZNF491,NEGR1,SHISA6,IGF1,IL6R,C2CD4C,CDH20,KLHL23,CYP27C1,PAXBP1,LMO2,SYTL4,HECTD2,MARK3,MBD1,CHIC1,EFHB,MEF2C,MEIS1,MXI1,MYH3,ZNF862,BEX5,NEK1,NFIX,SLC11A2,OCRL,CLDN11,PCDH8,PCDH9,PRTG,PDE4A,PDE4D,SERPINI1,CCSER2,SNX10,GPSM2,MAPKAP1,RETREG2,PILRA,SH3KBP1,PPP2R2B,PPP5C,PRKCB,EPDR1,DCHS2,SAMD9,SNRK,PIGG,PTK2,PTPN13,PTPRB,PTPRO,RIPOR1,MARCH1,PID1,CEP97,FAM66C,ENOX1,RASGRF1,RBBP6,REV3L,RGS4,RIC8B,LGI2,ROBO1,ROBO2,CCDC102B,RPL15,MCMBP,TCP11L1,SATB1,ATXN2,PEAR1,SEC14L1,SGK1,PPM1E,FERMT1,FBXO11,NLGN1,DZIP1,NUBPL,FAM81A,SEPHS1,LGI3,RCOR3,MBD5,SNRPN,TMCC1,PDZRN3,SOX11,DOK5,HECW1,MYCBP2,KDM4C,SPTB,TSPYL2,NFASC,ZNF621,ATP10B,ITPRID2,NKAIN2,ELOVL4,SEPT3,NUDT10,ANKRD28,DNMBP,ALG1,MGRN1,TCF4,TPCN2,DOCK9,PCDHB10,DICER1,ZNF106,TIAM1,RELL2,KAT6B,SYNPO2,TRPS1,FLRT2,PLEKHH2,ZNF709,MGAT5B,VLDLR,CLDND1,GUSBP1,XRCC4,ZNF24,ZNF28,LYPD6,SPHK2,ZNF177,ZNF189,FTSJ1,ZFAND5,DHX33,SLC38A1,SEMA3B,GAL3ST3,FIP1L1,ST7,CASC15,FXR1,NETO1" MicroRNA hsa-miR-300:mirSVR_highEffct hsa-miR-300:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.24E-107 1.26E-103 5.66E-106 5.21E-105 270 1509 "ACADM,CCDC85A,ADRA1B,KCTD16,ABCD2,PCDH10,FAM135A,LRFN1,APAF1,ARNTL,ZBTB10,NUMB,EIF4G3,STX16,ATP2A2,DOCK11,CARMIL3,BACH1,DST,NAE1,RAB29,IL33,THSD7A,KALRN,SPAG9,ZNF501,LDB2,MAGI1,CFL2,B4GALT6,RAB33A,RAB28,NGEF,ABCG2,HECTD1,CNR1,ARMC8,AHCTF1,ZNF521,TRIM69,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,CST3,PLXNA4,BOC,DOCK4,HDAC9,ARHGAP24,GIT2,ARMCX2,YTHDC1,ZC3H11A,FAM107B,CHRDL1,RAB39B,DMTF1,DPP6,E2F5,EBF1,SNX29,ANKRD46,CNNM1,KLHL5,FSD1L,PHF20L1,MBNL2,KMT5B,KCTD3,EIF4G2,TENM1,PAN3,EIF1,VPS13B,EPB41,EPB41L2,LRRC17,EPHB1,DENND4A,CEP85L,RRAGB,DLC1,CEP78,ZNF589,FGF1,POLR1B,BAIAP2,ATP5PD,FOXF2,PCYOX1,SYNCRIP,FOXO3,NBEA,SMC2,ATP6V1H,PRELID3A,STAU2,MSANTD4,GABRB3,GAD1,GALC,RAPGEF6,MTHFD2,C15orf41,KIAA1841,AHDC1,RUNDC3A,TNRC6A,MAP7D2,KCNMB4,ADGRA3,TDRKH,GPR34,PCLO,GRIA2,GRM8,AP4S1,PSIP1,ADAMTS6,FAM222A,IRAK3,MIER3,TCEAL6,ZNF546,ZIC5,RBPJ,ZNF678,JAK2,KCND2,KIT,STXBP5,HECTD2,MAP4,MARK1,MATN2,MBNL1,LRP1B,MEIS2,SRSF12,MITF,ZNF680,MSR1,MYO9A,NEXMIF,P2RY13,NF1,CNOT4,CNTN3,PCDH8,PDE1C,ENPP2,ZNF655,FAM218A,CCSER2,XRN1,KCTD15,NLE1,PLCL1,PURG,PMP22,ING3,FA2H,KANSL1,RANBP3L,PRKACB,CEP41,MAPK4,GDPD1,SNRK,PTCH1,ANKHD1,TMEM260,PEX2,TMEM231,RAP1GDS1,OXR1,MSANTD2,REV3L,GTDC1,SLC25A36,RIC8B,ZNF532,GSTCD,ROBO2,RPS20,ABCA11P,SALL1,SEMA6D,SATB1,SCN7A,FNIP1,TNFRSF19,CASC3,SCAF8,KIF21A,SH3GL3,PPM1E,CHD9,R3HDM2,CNKSR2,SYBU,WDR37,PPP4R3A,EPN2,SLC6A8,ATF7IP,GKAP1,INAVA,MBD5,KIF13A,TRERF1,SP4,SPTB,IQSEC2,RBM26,DDN,LMO3,CLSTN2,SAMSN1,SSTR2,ZC4H2,NXT2,SEPT8,ARHGEF9,ZEB1,SYNE1,PCDHB4,FRYL,HIF3A,TEK,DICER1,ZFPM2,ZMAT3,NACC2,HEY1,ACTR6,ASXL3,NR2E1,BEX4,R3HDM1,KAT6B,TP53BP1,TP53BP2,TRIO,TRO,SSBP2,ZKSCAN5,SGK3,UBE3A,USP1,ZNF709,TBC1D15,VSNL1,PCDH20,ZBTB14,MICU3,LYPD6,ANKS1B,UPF3A,EMSY,MDH1B,NAV3,DNAH10,FAM13C,AMN1,PHTF2,NETO1,CPNE4,JPH3" MicroRNA hsa-miR-1255a:mirSVR_lowEffct hsa-miR-1255a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.73E-107 2.09E-103 9.36E-106 8.62E-105 287 1709 "DGCR6,ASIC1,SYS1,GALNT16,BRAP,PTCHD1,ZNF578,C1QTNF3,FAM135A,AMPD3,LRFN1,OGT,MAP4K3,PPFIA4,PKP4,APAF1,UPRT,PHYHD1,CPNE5,SPTBN4,MARCH3,ZBTB10,NCOA1,STX16,ZNF583,ATP6V0A1,TTLL9,AZGP1,BID,DST,ARHGEF7,SCAPER,SGCE,CFAP410,CACNA1B,CACNB4,CAPN3,SPAG9,CBR1,CD86,ENTPD2,ARHGEF2,LRRFIP1,TIGD7,CLGN,DIS3L,SRSF11,TAOK2,PPT2,DGCR9,SRP14-AS1,CNGA3,FHL5,CNN3,AHCTF1,MYRIP,CNRIP1,CPS1,FAM171B,MROH8,SOCS5,PDE4DIP,CNTNAP2,PHF14,FAM131B,RIPOR2,HDAC4,TMEM170A,AIF1L,PITPNC1,ARMCX2,MFAP3L,C2CD2L,SGSM2,WDR20,ZNF582-AS1,DMTF1,CASP8AP2,PDCD6IP,DTNA,TOM1,ABCC5,GOLT1B,E2F5,WDPCP,EDNRB,FSD1L,MBNL2,RASA4,TMEM35A,STARD3NL,ENO2,COQ7,GPHN,STX2,DENND4A,ADGRV1,GMPR2,CORO2B,CEP78,FDFT1,KAT8,FER,FGF12,FGF13,FOXO3,SLC37A3,NOP56,AKAP3,NBEA,UFM1,TPK1,ATP2C1,DLL3,STAU2,ABLIM2,MEGF10,ZNF559,DISC1,GATM,GCK,SRCAP,MSTN,GPR162,GGTA1P,PPARGC1A,RUNDC3A,ZNF276,CRCP,TCERG1,RNPS1,STARD3,KDM2B,POLL,GNAO1,LILRA2,PCLO,DIDO1,GRM2,ZBTB49,FAM107A,SLC2A6,NXPH3,BACH2,MIER3,SYNPO,ZNF491,CPT1C,SHISA6,SMAP1,ICA1,SLC35G1,METTL21A,STXBP5,KTN1,LAMP2,STMN1,LIFR,LIMS1,NCOA7,PIK3AP1,MAPT,MATN2,MATN3,TM6SF1,AFDN,MPP2,DBNL,COMMD5,PTOV1,MXI1,MYO6,MYO7A,MYO9A,NEXMIF,FXYD7,NEK1,NELL2,NFE2L2,NRCAM,SMIM11A,NTRK2,NUCB2,OCRL,OGG1,PCDH9,PDE4A,PFKFB2,SEMA5B,SNX10,NLE1,PLIN1,MTRF1L,PNMA3,SDK2,MAGEL2,POU6F1,PRKACB,PRKCB,GRAMD1C,MASP1,VPS13C,PIGG,MTMR10,PTPRD,ZSCAN2,IQSEC3,RAP1GDS1,MSANTD2,PRRT2,RNASE1,NUDT11,LGI2,TMLHE,ROBO1,RORB,ATP8B4,ATAT1,NCBP3,FAM192A,TNFRSF19,SCAF8,FAM102A,ASAP3,DZIP1,ANKRD6,WDR37,SLC12A2,ELMO2,SLC22A4,GKAP1,CDK5RAP2,SNAP25,FAIM2,SNRPN,TSNAXIP1,KDM3A,IQSEC2,TSPYL2,TROVE2,POGZ,ITPRID2,STX1A,KANK1,JMJD6,ARHGEF9,SYP,SLC37A2,TAL1,SIN3B,ZEB1,DOCK9,PUM2,FRYL,ITGB3BP,AP4E1,ENHO,MTMR14,TMPO,FAM124A,CSMD1,TPM2,C9orf85,RGMB,STXBP4,TRPM2,TSC1,HSPBP1,BCL2L13,VLDLR,GUSBP1,XPO1,ZNF24,NDRG4,TCEAL7,REEP1,DNALI1,LINC02210,VPS35L,PPP1R3F,FAM13C,FZD3,UBE3B,KAT6A,RNF170,ZNF30,JPH3" MicroRNA hsa-miR-26b:mirSVR_highEffct hsa-miR-26b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.78E-107 2.12E-103 9.44E-106 8.70E-105 280 1627 "ACADM,CLK4,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HECW2,HACE1,TXNDC16,SMIM17,SEMA6A,ALCAM,LRCH2,EP400,APAF1,APC,TNRC6C,RGS20,CDK13,MARCH3,CCDC74A,SLC4A4,LINC00847,BID,GPR146,BMPR1B,DST,ST3GAL5,FUBP1,SCAPER,JAZF1,WASF1,KALRN,VXN,KRIT1,USP6,C1orf52,LARGE1,SRSF11,SOCS6,CHN2,CLCN3,CLTC,QKI,TMEM184B,CNR1,AKAP7,COL4A5,AHCTF1,BAG4,CLOCK,C2CD2,RBM39,HAPLN1,GDA,SNCAIP,ARHGEF10,PLXNA4,DZIP3,ERC2,GREB1,RUBCN,CYBB,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,KCTD8,DAPK1,PITPNC1,JAKMIP2,HEPH,MFAP3L,C2CD2L,PLPPR4,SACS,WDR20,EXOG,GRIN3A,DMD,USP3,DPYSL2,PDCD6IP,DTNA,FCF1,KLHL5,TMTC1,FSD1L,EGFR,EIF4G2,EIF5,CALCRL,PAN3,VPS13B,LRRC17,EPHB1,ETV1,FAM198B,RPS6KC1,TMEM132C,CEP78,GORAB,FGF14,MEX3B,SEMA4D,SLC37A3,NOP56,UFM1,NEURL4,ZNF44,IQGAP2,DISC1,ACSS1,SRCAP,PPARGC1A,TNRC6A,ZNF638,KCNMB4,GRB10,DIDO1,CLASRP,LINGO1,PSIP1,ADAMTS6,UBE2QL1,ZHX1,MIER3,HNF4G,CELF5,MSL1,ZIC5,RBPJ,IL6ST,FAM69A,KCND2,CREG2,LIG4,SMAD1,MAP2,MARK1,MAT2A,MATN2,MITF,AFDN,MMP16,ZNF680,BLOC1S2,ZNF92,MXI1,MYO9A,CCDC13,NEK1,CNOT4,SLC11A2,CNTN3,PCDH8,PCDH9,SLC10A4,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,FAM216A,PLCL1,PCDH18,PURG,MAPKAP1,ING3,RETREG2,FA2H,MINDY2,PPM1B,PPP2R2B,RANBP3L,CEP41,GRAMD1C,HYDIN,DIRAS2,VPS13C,PIGG,PTK2,ZSCAN32,PTPN13,PTPRD,TTC13,ZNF615,PPP2R3C,CEP97,TMEM255A,ZCWPW1,RADX,UBR7,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,GSTCD,ARMH4,GLDN,MEG3,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,GALNT10,MRAS,KIF27,CHD9,FBXO11,NLGN1,ZNF430,CCDC88A,TET1,CPEB4,MYH15,ANKRD36,LIMCH1,CMTR2,TMCC1,USP33,ZC3H13,CLASP2,TROVE2,LARP4,ERBIN,STAC2,NECAB1,SYNE2,NUDT10,PLCB1,ANKRD28,PJA1,DNMBP,FAM208A,ADGRL3,KLHL4,TCEA1,USP32P1,FRYL,C18orf54,AP4E1,ERCC6L2,FAM124A,AMACR,STXBP4,PPIL6,DCBLD1,TSN,ANKRD20A2,TTC3,ZKSCAN5,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,ZNF24,KCNT2,MKRN3,ZBTB38,ANKS1B,SLC30A4,EMSY,PRTFDC1,CIAPIN1,MDH1B,MPPE1,WNK3,PDSS2,FAM13C,JMJD1C,RNF170" MicroRNA hsa-miR-424:mirSVR_highEffct hsa-miR-424:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.04E-107 2.26E-103 1.01E-105 9.26E-105 268 1490 "ABCF1,KCNH8,NCKAP5,SYS1,CCDC85A,GALNT13,ADD2,AXIN2,KIAA1211,ADRB2,AP2A1,AP2A2,SRPX,ARHGAP20,ALK,OGT,ANK2,BCAS1,PPFIA3,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,NCOA1,SLC4A4,TTLL9,MPDZ,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,CA8,CACNA1B,KALRN,PTBP2,VXN,CAST,SPAG9,RUNX1T1,ARHGEF1,PPT2,CLCN3,TPP1,QKI,SLC4A8,TBPL1,MYRIP,SLC35F1,SEC31B,CLOCK,PREPL,AKAP12,CRYM,LRIG1,SOCS5,ERC2,DCAF4,USP6NL,CYBB,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,DCAF8,KCTD8,ARMCX2,YTHDC1,JAKMIP2,MYEF2,SPOCK3,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,PHF20L1,MBNL2,PLEKHA1,PAN3,RCAN2,DENND4A,CEP85L,SPEG,EYA1,NRN1,ACSL4,FGFR1,FHL1,SUCO,MEX3B,RGPD5,SLC37A3,UFM1,PDLIM5,ZNF605,CELF1,CSPG5,NSG1,FYB1,CHL1,DISC1,SESN1,USP19,PCDH17,GHR,FERMT2,GPD2,PCLO,GRIA2,ZNF496,RNF165,RASSF8,ZHX1,FRMD3,HSF2,MSL1,RBPJ,NIM1K,INPP1,NME9,SLC35G1,KCND2,KIF2A,KIF5A,LAMP2,MAP4,LYPLAL1,MARK3,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,THYN1,RTL5,NDP,NOVA1,SLC11A2,NTRK3,GPR137C,CNTN3,ETFRF1,PCDH9,PDE3A,PDPK1,SLC10A4,PIK3R1,JAKMIP1,PSAT1,RETREG2,EPB41L4B,RASGEF1B,MAPK9,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,CNTLN,STK32A,ZSCAN32,PTPRD,PID1,TMEM255A,FAT4,RBBP6,HKR1,KHDRBS2,ZDHHC14,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,RPL15,ARMH4,FBXW7,ABCA11P,KCNIP1,ZNF568,SALL1,MAPK12,SEMA6D,SATB1,ATXN2,SCN8A,TNFRSF19,COPZ1,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,SHC4,HKDC1,FHOD3,NLGN1,ANKRD6,FAM81A,ARHGEF40,CCDC88A,KBTBD4,SLC22A4,CPEB4,RCOR3,SNAP25,MBD5,UNC5B,ZC3H13,TSPYL2,NFASC,NKAIN2,PRRC2C,SYNE2,SYPL1,C12orf76,PJA1,TBCEL,TCEA1,SATB2,TPCN2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ERCC6L2,TPM2,RUNDC3B,LGI4,ZNF28,TRIM9,FSTL5,EML6,ANKS1B,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,FBXO36,ADAMTSL3,FXR1" MicroRNA hsa-miR-624:mirSVR_highEffct hsa-miR-624:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.43E-107 3.60E-103 1.59E-105 1.47E-104 246 1252 "KLHL32,ADD1,KIAA1211,DPY19L2P4,SLC24A4,MTUS1,PCDH19,AGT,RTL9,OSBPL1A,NME5,OSBPL8,FAM135A,SYT13,DPP10,LRCH2,LCORL,PKP4,APAF1,UPRT,TNRC6C,USP37,LGR5,ARNTL,PDE8B,RASL11B,CHID1,ATP6V1G2,ADAM23,CFLAR,BMPR1B,DST,SCAPER,SGCE,RAB29,CACNA1A,LURAP1,THSD7A,PTBP2,CAST,LDB2,USP6,USP2,MTMR7,SYNGR3,CD38,ZMYM4,CACNA2D2,CFL2,SRSF11,SOCS6,CHN2,TMEM184B,ARMC8,AKAP6,COL9A1,RGS6,VAC14-AS1,PDE4DIP,PHACTR3,PLXNA4,DZIP3,ERC2,GREB1,PUM1,CCDC144A,DOCK4,HDAC9,TM9SF4,LIN54,ARMCX4,ELMSAN1,ZNF804A,RAB39B,DMTF1,DPH1,RCAN1,ECM2,MAMLD1,PHF20L1,KMT5B,CALCRL,VPS13B,ENPP6,SRRM1,DENND4A,CEP85L,ADGRV1,SCML2,GORAB,VTI1B,SEMA4D,FLT1,EFCAB2,NBEA,UFM1,CELF1,FYN,MEGF11,GABBR1,GALNT15,ACSS1,LRRC37A6P,GATM,PPARGC1A,TCERG1,DBF4,TNRC6A,GLUL,GRIA2,ADAMTS13,BVES,RASSF8,HNMT,SMAP1,RBPJ,ZNF678,JAK2,METTL21A,LAMP2,HECTD2,NCOA7,SMAD1,PIK3AP1,MARK1,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,BLOC1S2,MSR1,MYO6,NDP,SFR1,NEK1,NF1,NFE2L2,NOVA1,NTRK2,IGSF11,CHAMP1,OPA1,CNTN3,PCDH9,PRTG,PDPK1,PFKFB4,ZNF655,XRN1,ZNF426,PRIMPOL,PPP3CA,KANSL1,PRKACB,EPDR1,PSMA6,QRICH1,ANKHD1,MTMR10,PTPRB,PTPRD,STRC,TMEM255A,FAT4,OXR1,RASGRF1,RASGRF2,RBBP6,RFX3,RNASEL,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,RPE,TCP11L1,LRRK2,AP1AR,SALL1,SEMA6D,FNIP1,CPEB3,CHD9,BTBD3,DHX30,CCDC88A,SLC12A2,ATF7IP,DMRTC1,SMARCD3,SNRPN,TMCC1,BDP1,FNBP1,DOK5,SP4,ZC3H13,MCF2L2,SPART,SS18,NXT2,MPRIP,STXBP1,PRRC2C,VPS13A,DNMBP,ADGRL3,DMXL2,SATB2,ZFP90,SYNE1,PCDHB4,PUM2,USP32P1,FRYL,VWCE,TEK,AKTIP,ERCC6L2,TP53BP2,ZKSCAN5,SGK3,FLRT2,XRCC4,ZFP37,ZNF28,ATP6V0E2,ZBTB38,ANKS1B,ZFAND5,SLC38A1,LINC02210,FIP1L1,RGS7BP,FAM13C,MRPL47,RTN4,UBE3B,CASC15,JMJD1C,RNF170,NETO2,NETO1" MicroRNA hsa-miR-491-3p:mirSVR_lowEffct hsa-miR-491-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.62E-107 3.70E-103 1.63E-105 1.50E-104 271 1527 "ACADM,CLK4,NDRG3,KLHL32,RNF157,AXIN2,PLEKHH1,BEND6,INTS2,ABCD2,ALK,DPP10,PHF12,PKP4,APBB2,MAGEE2,USP37,CDC14B,PPP4R4,CASK,ZFYVE28,ARRB2,CDK13,ZBTB10,SLC2A11,DPY19L3,DOCK11,ADGRB2,ADGRB3,MPDZ,SEC11C,BCHE,FUBP1,JAZF1,RAB29,CACNB4,CALB1,CAST,LDB2,METTL6,MAGI1,CLGN,FOXN3,SOCS6,CHN2,RAB28,NRXN3,FBXO7,C4orf33,TMEM184B,CNN3,CNTN1,PCYT1B,FAM149A,AKAP6,AKAP5,TBPL1,RBM39,GDA,SNCAIP,SIPA1L1,PDE4DIP,CNTNAP2,CTH,PUM1,PPP6R2,MYADM,KATNAL2,ZFYVE16,ZNF337,LONRF1,KIAA0586,KCTD8,IST1,PITPNC1,YTHDC1,FBXL5,DDX46,SPOCK3,MTX3,NR1D2,DMTF1,CASP8AP2,FARSB,E2F5,E2F6,EBF1,EDNRA,KLHL5,TENM1,RGS17,COQ7,ENPP6,STX2,CEP85L,ETV1,GMPR2,ABCA8,TBC1D16,ACSL4,CEP78,SEC24B,MED12L,FGF13,POLK,SUCO,MEX3B,IP6K2,SEMA4D,NELFCD,NBEA,HVCN1,CSPG5,SDCBP2,MEGF11,GABRG1,GALC,B4GALNT1,ERAP1,KIAA1841,NEU3,NFU1,TOX3,KDM2B,RAB40B,ADGRA3,GPD2,TDRKH,FUT10,CNTRL,ATP2B1-AS1,BTN2A1,HAS2,USP51,SMAP1,EID2B,NKD1,RBPJ,IL12A,NME9,KCNB1,CREG2,IPO5,LAMP2,PAXBP1,ZFYVE27,MBD1,MBNL1,CHIC1,LRP1B,SHC3,MEF2C,MGAT3,MIA2,COL28A1,N6AMT1,MYO6,ZNF862,BEX5,ZC3H12B,NDP,ALDH1L2,CNOT4,NRCAM,SMIM11A,NTRK2,PCSK1,PDE4D,ZFYVE21,PCDH18,PDZRN4,SCHIP1,ING3,POU6F1,TATDN3,PPP2R5E,RASGEF1B,CNTLN,ANKHD1,ELOVL2,PTPRB,PTPRD,EML5,PTPRG,PPP2R3C,PID1,SH3TC2,HKR1,KHDRBS2,REV3L,FIGN,RIC8B,PBRM1,LGI2,CCDC82,TMLHE,CARF,ROBO1,NEK11,EPHA10,SEMA6D,SATB1,CSRNP3,SEC14L1,SUPT20H,SH3GL3,FERMT1,KIF16B,CPEB3,ANKRD6,PREX2,CCDC88A,BTBD7,TET1,ZFP1,RCOR3,MBD5,KDM4B,SOX11,KDM3A,MCF2L2,LMO3,ATP10B,ITPRID2,SSTR2,MPRIP,DIP2A,KANK1,VPS13A,SYN2,TACR1,ADGRL3,TBCEL,TCF4,DMXL2,SATB2,ZEB1,RPGRIP1L,FRYL,DICER1,ITGB3BP,AP4E1,TIAM1,CHST5,TRPS1,TSN,RPL7L1,EIF4ENIF1,UBE2H,OSBP2,RICTOR,XPO1,ZIC2,ZNF711,ZNF24,ZFP41,AGMO,LYPD6,CELF4,ZBTB38,TMEM237,ZNF184,SLC30A4,CADM2,RNF103,NAV3,PDSS2,FRMD6,NETO1,LAS1L,FAM198A" MicroRNA hsa-let-7a-2*:mirSVR_highEffct hsa-let-7a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.16E-107 4.01E-103 1.76E-105 1.62E-104 245 1242 "RALGAPA1,DGCR6,KCNH8,CLK4,KLHL32,AXIN2,ADRA1D,BEND6,OSBPL1A,TBC1D14,SPARCL1,ABCD2,PCDH10,UNC79,FAM135A,SYT13,OGT,MAP4K3,PHYHD1,BCAS1,CHRD,NUMB,RASL11B,ATP2A2,ADGRB2,BCHE,NRP2,SYNJ1,MTMR2,IL33,KALRN,PTBP2,AP4M1,LRBA,MAGI1,SRSF11,CHN2,NDST3,LHX2,LY86,AKAP7,IQCK,LETMD1,AKAP12,HAPLN1,CS,LRIG1,SOCS5,PDE4DIP,SLITRK5,USP6NL,HDAC9,TCAF1,KIAA0586,IST1,IP6K1,ALKBH8,SNAP91,DLX1,HS3ST2,USP3,DNAH9,NR1D2,CDON,CPEB2,DTNA,ABCC5,E2F5,EBF1,EDNRB,PHF20L1,MBNL2,EGR3,TENM1,PLEKHA1,MRNIP,RGS17,GPHN,CEP85L,EYA1,CLVS1,DLC1,CEP78,FGF13,MEX3B,SYNCRIP,SLC37A3,DCTN2,C2orf88,NBEA,HVCN1,STAMBP,CAMKK2,CSPG5,MEGF11,ZNF559,KIAA1841,AHDC1,PPARGC1A,GLI2,KDM2B,GNAL,FERMT2,GRB10,DIDO1,C1QL4,ZNF496,CIT,KAT7,LINGO1,ARHGAP36,BACH2,HNMT,ZNF491,SHISA6,SMAP1,SOWAHA,KNDC1,INSM1,METTL21A,KCND2,KCNH2,KCNJ16,STXBP5,LAMP2,NCOA7,LSS,ASPRV1,MAP4,MBNL1,SHC3,MN1,HS6ST3,MYCN,NCF2,NPTX1,NTRK2,NTRK3,CLDN11,PCDH8,PCSK1,PCSK5,ENPP2,NLGN3,PIK3C2A,ZNF655,FAM218A,ZFYVE21,ING3,TATDN3,SAMD9,WBP1L,SNRK,PTK2,TMEM260,EML5,USP47,RASGRF1,REV3L,PRIMA1,SLC25A36,PBRM1,SNX22,NEK11,MAP6D1,MEG3,TRAPPC13,RMI1,SALL1,SGK1,ARX,KIF16B,CPEB3,FNDC3A,ANKRD6,WDR37,SLC22A4,SNCA,MBD5,KDM4B,PDZD2,KDM3A,MYCBP2,ZC3H13,ATP10B,CLASP2,TROVE2,ZNF302,ZC4H2,LARP4,NKAIN2,ERBIN,STAU1,NSFL1C,KLHL7,NUDT10,DNAJC9,PLCB1,MMS19,CAMTA1,TAL1,ADGRL3,ZEB1,DOCK9,FAM189A1,PCDHB4,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SLC44A1,TMPO,R3HDM1,KAT6B,NPL,RGMB,TRIO,RPL7L1,EIF4ENIF1,PLEKHH2,BCL2L13,VLDLR,ZIC2,MKRN3,ZNF142,REEP1,FTSJ1,EMSY,MDH1B,NAV3,PCBP4,MPPE1,PDSS2,FAM13C,KAT6A,FBXO36,FAM219B,JMJD1C,FXR1,NETO2,SENP7" MicroRNA hsa-miR-484:mirSVR_lowEffct hsa-miR-484:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.89E-107 4.41E-103 1.93E-105 1.77E-104 298 1846 "ABR,SYS1,XKR4,CCDC85A,ADD1,ADD2,AXIN2,KIAA1211,FAHD2CP,BEND6,ZNF608,OSBPL1A,OSBPL8,CARNS1,SYT13,ZNF687,AMPD2,AMPD3,UPRT,BCAS1,TNRC6C,LGR5,SHROOM2,CADPS,CCAR2,SLC4A4,STX16,SLC2A11,ADAM23,RGS9,NRP2,ZNF599,CFLAR,KSR1,ARHGEF7,C5,GPC2,WASF1,CALM1,KALRN,CAMK2A,CAMK2B,SPAG9,KRIT1,METTL6,CD86,CDC25B,ZBED1,EVI5L,CFL2,RCBTB2,PLEKHB1,NDST3,RAB28,CLCN3,IGLON5,CNTFR,IQCK,COL11A2,BAG4,IGDCC3,CRMP1,HINFP,CSF1R,SEC24C,SUSD5,CST3,PHF14,RUBCN,ARHGAP32,GAPVD1,DCAF8,ZFYVE16,LIN54,MATR3,MAML1,DGKG,SPOCK2,IP6K1,PABPC5,ARMCX4,PITPNC1,HEPH,C2CD2L,TMEM130,SGSM2,WDR20,ZNF582-AS1,EXOG,HS3ST2,DNAH9,CD99L2,SHANK1,DPP6,ACOT8,PDCD6IP,DTNA,PHC2,FCF1,CNNM1,YAF2,FAM13A,PHF20L1,EGFR,EGR3,TMEM132E,RASA4,GOLGA7,TENM1,TNK2,EPB41L2,ENPP6,MRPL10,NRN1,FAM198B,ZNF589,GTF2IRD2,UBE2E3,MEX3B,IP6K2,AGAP2,SEMA4D,CAMKK2,GALNT15,ZNF234,DISC1,INPP5K,ARFIP1,GDF9,SESN1,GFER,GHR,TXNL4A,GLI2,MSL3,GPD2,TMEM121B,STMN2,GRB10,ADAMTS13,PRDM5,SOX21,GUCY1B1,TOX2,MAN1B1,SYNPO,MSL1,MYLK2,ZIC5,TJAP1,INPP5B,SLC35G1,KCNK3,GATD1,KHK,KIF5A,A1BG-AS1,LAMP2,STMN1,HECTD2,MAT2A,MEIS1,DBNL,SAMD5,MYCN,MYO7A,HNRNPM,NF1,NOVA1,OGG1,P2RX7,P2RY1,PCDH9,PCSK5,GNG2,PFKFB3,SEMA5B,TMIE,CCSER2,ZFYVE21,ANKRD16,PMP22,MAPKAP1,SDK2,SEPT4,MBOAT7,PPP1R1A,NKAIN4,CEP41,EPDR1,MAPK10,HYDIN,GDPD1,MASP1,WBP1L,CNTLN,ANKHD1,PTPRH,C1orf109,TMEM231,MARCH1,ACSS3,RAD17,CCDC40,SUSD4,RAP1GDS1,RASGRF1,RET,PRRT2,ERI2,RFX3,RIC8B,CYB561D1,KIRREL1,CCDC102B,KIAA0895L,ADAL,MAP6D1,ATAT1,DGLUCY,SARS,SEMA6D,FNIP1,CASC3,FOXRED1,MRAS,FAM102A,ARX,SHC4,CHD9,FBXO11,FNDC3A,ST6GAL1,NUBPL,ARHGEF40,SLC9A5,SLC11A1,ELMO2,ATF7IP,EPC1,ABTB1,SMARCD3,USP33,PDZD2,TSNAXIP1,SPP1,DBNDD2,LHPP,TROVE2,POGZ,ITPRID2,ZC4H2,ZSCAN29,NEK4,STXBP1,PRRC2C,ARHGEF9,SYPL1,COBL,SYT5,MGRN1,ZEB1,TRIM2,RPGRIP1L,SYNE1,NAT16,RNF216P1,GPR161,CDH22,ARL10,MTMR14,TMEM9,ACTR6,SMUG1,AMACR,TRPS1,RUSC1,ZKSCAN5,LINC00689,PLEKHH2,VLDLR,LAT2,GUSBP1,ZIC1,ZNF74,NDRG4,TMEM237,ZNF213,SLC30A4,ZXDA,PRDM10,HPS4,MPPE1,EPM2A,KAT6A,HNRNPA3,FBXO36,TRAM2-AS1" MicroRNA hsa-miR-588:mirSVR_lowEffct hsa-miR-588:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-106 5.82E-103 2.53E-105 2.33E-104 286 1704 "RALGAPA1,XKR4,TMEM132B,BRAP,MTA3,AGT,KCTD16,OSBPL1A,KIAA1324,BEGAIN,DOC2A,CDC42BPA,DPP10,PI16,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,USP37,MARK4,CCDC74A,PCDHGB4,SLC2A11,RNF182,N4BP2L1,KSR1,BMP7,SYNJ2,CASTOR3,BAIAP3,DDR1,MTMR7,P2RX6,ARHGEF2,ASIC3,EPS15L1,RAB26,CNR1,CNTN1,COL9A1,CRY2,ANKRD44,RGS6,CSNK1G3,RASGEF1C,ERC2,CTH,KIAA0408,ARHGAP32,MATR3,DNAL1,ARMCX4,RUSC2,SGSM2,TMCC2,EXOG,RAB39B,CD99L2,CPEB2,DOCK2,DPH1,DPP6,DTNA,DUSP9,ABCC5,DNM1L,TMTC1,IRAK4,COPS4,VPS13B,EPHB1,ENPP6,NCALD,ETV1,VPS26C,ANKMY1,PTK2B,CORO2B,STRADA,GTF2IRD2,FGFR3,IP6K2,PCYOX1,FOXO3,EVL,TMEM175,CAMKK2,CELF1,STAU2,MSANTD4,TVP23A,GABRA3,RAPGEF6,INPP5K,GATM,SRCAP,ADAM28,GGT5,RUNDC3A,TNRC6A,ZNF638,GNAL,LNX1,GPD2,TMEM121B,GRB10,PLCD4,SERP2,GRM2,BTN2A1,RNFT2,MAP4K5,MUM1,RASSF8,HLF,VSIG4,HMGCR,CPT1C,HSF2,C2orf72,KNDC1,KCNK3,A1BG-AS1,STMN1,HECTD2,MAN2A2,ZFYVE27,MAP4,MAP6,MID1,PPM1L,DBNL,COMMD5,PTOV1,LYRM9,LAYN,CCDC13,NF1,NPTX2,NUCB2,OGG1,TREM2,PCDHGC3,CDK18,ENPP2,PFKFB2,PFKFB4,PKD1,JAKMIP1,TRHDE,FA2H,EPDR1,WBP1L,DEF8,WDR25,PTX3,ZNF615,TUG1,TMEM231,CEP97,RAD51D,ZNF793,NWD1,ZDHHC14,GTDC1,UBR7,RGS12,SLC25A36,RNASEL,ROBO2,RORB,MRAP2,EPHA10,RPL15,BAALC,ADAL,RPS6KA2,ABCA11P,CLIP1,STX1B,AP1AR,DGLUCY,MAPK12,SATB1,MRAS,RASA3,HKDC1,FNDC3A,WDR37,ABLIM3,PEX26,DHX30,PKNOX2,RADIL,ARHGEF40,CCDC88A,BTBD7,ATF7IP,LGI3,CDK5RAP2,MBD5,CMTR2,SNRPN,DOP1A,BDP1,KDM4C,UNC5B,NFASC,ATP10B,ITPRID2,LARP4,NXT2,ST5,ZSCAN29,SEPT8,CEP68,KANK1,ARHGEF9,ARC,COBL,ANKRD28,TACC1,MCF2L,PDLIM2,KLHL4,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PHF24,PCDHB10,PCDHB3,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,AP4E1,MTMR14,FAM124A,RIMBP2,CSMD1,TPM2,CHST5,SMUG1,ELP5,STXBP4,TRPS1,PPIL6,CLHC1,UGT8,PLEKHH2,MGAT5B,CCDC136,CCDC14,VLDLR,RBFOX3,XPO1,ZNF540,AMZ1,SLC30A4,EMSY,GDPD5,LINC02210,ADAMTS9,GAL3ST3,DNAH10,TMEM63C,FAM219B,RNF170,IFT88,PRRT4,FAM198A,SPATA13" MicroRNA hsa-miR-592:mirSVR_lowEffct hsa-miR-592:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-106 8.07E-103 3.49E-105 3.22E-104 279 1624 "KCNH8,CCDC85A,GALNT13,AXIN2,KIAA1211,PTCHD1,SLC24A4,PCDH19,HACE1,SEMA6A,SRPX,CEP126,BIN1,APAF1,AQP6,SPTBN4,STK33,DNAH17,PCDHGB4,RNF182,MYOM1,LINC00847,MIR9-3HG,BMPR1B,CASTOR3,CA12,CACNB4,VXN,RHBDL1,PRC1,SEPT7,CCPG1,SRSF11,PLEKHB1,DGCR9,QKI,MAP4K4,AKAP5,RCHY1,TOGARAM2,SLC35F1,CLOCK,AKAP12,SNCAIP,CSF1,CSF2RA,SEC24C,OSBPL3,PDE4DIP,KIAA0040,PHF14,PLCXD3,PNPLA8,RIMS2,USP6NL,KIAA0408,EARS2,AIF1L,YTHDC1,USP3,NR1D2,CDON,DTNA,DNAJB6,DNM1L,EDNRA,FCF1,TMTC1,YAF2,SUGP2,EGFR,GOLGA7,TENM1,CALCRL,RCAN2,STX2,ZNF549,DNAJC27,KATNAL1,NRN1,TAOK3,PRKAG2,FHL1,SCARA3,MEX3B,PCYOX1,SYNCRIP,AGAP3,FOXO3,EVL,FLT1,ANKFY1,PSD2,C2orf88,WDR83,MSANTD4,TVP23A,MEGF10,GABBR1,GABRG1,IP6K3,ZNF559,DISC1,CPLX2,GATM,TUBGCP4,SULT1C4,PCDH17,BRD8,ZNF276,COPS8,ZNF638,MAP7D2,GPT2,WDFY3-AS2,LILRB4,STON1,ADAMTS13,GRM2,SOX21,ADAMTS6,HAS2,UBE2QL1,BACH2,HLF,ZDHHC15,NEGR1,CPT1C,IDH3A,FAM95B1,MYLK2,IGF1,RBPJ,KCND2,KCNH2,KIF5A,KTN1,NCOA7,MAN2A2,MAP6,LYPLAL1,MBD1,MBP,CHIC1,TM6SF1,MEIS1,MEIS2,KITLG,MXI1,NFYA,SLC11A2,IGSF11,OPA1,OXTR,PCDHGC3,PCSK5,PDCD2,PDE3A,OLA1,ZDHHC8,PIK3C2A,MTRF1L,LRP12,EXOSC10,TATDN3,PKIA,MAPK10,BCAS3,WBP1L,SNRK,BDNF-AS,PTPRN2,PEX2,PID1,RBBP6,KHDRBS2,ZDHHC14,ERI2,GTDC1,RGS4,RIC8B,RNASEL,CCDC102B,FBXW7,BAALC,STX1B,ATXN7,STUM,FERMT1,SHC4,CHD9,R3HDM2,ANKRD6,NUBPL,SLA,PPP4R3A,BTBD3,FAM214B,SEPHS1,SLC22A4,CDK5RAP2,SNRPN,TMCC1,DOP1A,PDZD2,NMNAT2,PEG10,ZC3H13,ARHGAP26,TSPYL2,ATP10B,CLASP2,ITPRID2,LARP4,NKAIN2,STAU1,CEP68,STXBP1,SUPT5H,PRRC2C,SYT1,COBL,FAM208A,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,OBSL1,PCDHB3,NSD1,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1-AS1,GPR161,TMPO,ZNF346,SYNPO2,TTTY15,LINC00689,FLRT2,BCL2L13,RICTOR,KCNK12,XRCC4,MICU3,MKRN3,TCEAL7,REEP1,TMEM237,POLR3H,SH3GLB2,GDPD5,TMEM178A,PPP1R3F,AMN1,DOCK8,HNRNPA3,JMJD1C,RNF170,FXR1,SOCS4,ST8SIA2,CPNE4" MicroRNA hsa-miR-3190-3p:mirSVR_lowEffct hsa-miR-3190-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-106 8.34E-103 3.59E-105 3.31E-104 294 1802 "SYS1,GALNT13,HFM1,CARNS1,AMPD3,EP400,PARG,APAF1,KCNAB2,MAGEE2,TNRC6C,CDK13,ZBTB10,SLC2A11,RIPK1,ADGRB1,LINC00847,DNAJC27-AS1,CFLAR,KSR1,SYNJ2,MTMR2,JAZF1,WASF1,KALRN,PTBP2,CH25H,RHBDL1,SPAG9,NFS1,ZNF501,KYAT1,CD38,LRRFIP1,CDO1,TIGD7,NUMBL,CBARP,SOCS6,TAOK2,CPNE6,RAB33A,NRXN3,QKI,SULT4A1,IGLON5,CNTN1,AKAP6,COL9A3,TOGARAM2,SLC35F1,CLOCK,ANKRD44,NCOR2,SIPA1L1,PDE4DIP,PPP1R16B,GREB1,DCAF4,RUBCN,HDAC9,DCAF8,ZFYVE16,LONRF1,KIAA0586,MAML1,TMEM170A,PABPC5,KIAA0753,C2CD2L,GUCD1,TMCC2,WDR20,SLC29A4,SLC25A18,DTNA,ECM2,FAM78B,TOM1,ABCC5,CNNM1,TMTC1,SUGP2,ASB3,IRAK4,C3orf18,TMEM35A,CALCRL,PAN3,RASGRP2,EPHB1,ERBB2,SIRPB1,GMPR2,MRVI1,FAM198B,SH3YL1,TAOK3,CEP78,FCGR3A,SLC9B2,FER,FHL1,POLK,SYNCRIP,ANKFY1,EFCAB2,WDR83,USP21,CAMKK2,KHDRBS3,HHIPL1,MPP6,HRASLS5,CHL1,GABRB3,B4GALNT1,IP6K3,ZNF559,TUBA8,ARFIP1,GPR162,USP19,GGT7,TTBK1,GLYR1,RAB30,MSL3,STARD3,DCLK2,LOXL3,GPD2,GPR12,CCDC184,PLCD4,ZNF496,RNF165,ZBTB49,AP4S1,RABL2A,SOX21,ATOH8,TOX2,PADI2,NXPH3,CPT1C,TCEAL6,LRRC75A,ICA1,MYLK2,IGF1,SCIN,ITPKA,ITPKB,JAK2,KCND2,IPO5,KTN1,CAMK2N2,LIG4,PACRG,MAP6,AQP11,ADAM11,MGAT3,ZNF680,MSR1,NRBP2,NINJ2,NME4,NOVA1,SLC11A2,SMIM11A,NUCB2,OGG1,PCDH9,CDK18,GPSM2,STRN3,POU6F1,PPM1B,KANSL1,RASGEF1B,PRKACB,MAPK3,EPDR1,MAPK9,MASP1,RELN,BCAS3,WDR25,CNTLN,TMEM260,PTPRE,CASTOR1,ZSCAN2,TTC13,TUG1,ZNF844,ENOX1,RADX,RET,RGS12,RIC8B,TMLHE,ARMC5,NEK11,SGSM1,ATAT1,SAFB,SEMA6D,ATXN7,PRCD,HSPA4L,SGK1,KIF21A,ARX,KIF16B,AMBRA1,FBXO11,PKNOX2,SEPHS1,RADIL,MYH15,IFT122,KIF13A,LMBRD1,TMCC1,KDM4B,DOP1A,DOK5,ZHX3,ZSWIM8,NMNAT2,TSPYL2,RBM26,NFASC,LMO3,POGZ,SAMSN1,ZC4H2,LARP4,SS18,SSPO,KLHL7,JMJD6,DNAJC9,SYPL1,SYT5,CAMTA1,ADGRL3,WSCD1,ZEB1,DOCK9,DICER1-AS1,KHDC1,AP4E1,THRA,TMEM9,RIMBP2,R3HDM1,TNS1,RASD2,TPM2,RGMB,STXBP4,KCNE5,TTC3,ZKSCAN5,FAM155A,UBE2H,UBTF,ZNF709,LMF1,RBFOX3,NPDC1,LGI4,ZIC2,ZNF28,TRIM9,ZNF138,CELF4,ZNF142,POLR3H,EML6,TFIP11,MFF,ADAMTS9,FIP1L1,PARP11,EPM2A,SMIM8,RNF170,NETO2" MicroRNA hsa-miR-4302:mirSVR_lowEffct hsa-miR-4302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-106 1.17E-102 5.02E-105 4.62E-104 308 1976 "RALGAPA1,DGCR6,ACHE,CLK4,ACTN1,NDRG2,PSMG3-AS1,UNC5A,SLC24A4,PCDH19,HACE1,KIAA1324,AK2,SEMA6A,ALCAM,ALK,SYT13,PITPNM2,FGD2,CCDC146,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,CASK,TMEFF1,SPTBN4,ARRB2,ATP2B2,N4BP2L1,DPY19L3,ATP6V0A1,ADGRB2,BCS1L,PROM1,WASF1,MYRF,CA8,DDR1,CACNB4,CALB1,CBLN1,CBR1,CCK,CCNH,RGN,SYNGR3,ENTPD6,LRRFIP1,EVI5L,CCPG1,CBARP,CNOT8,ABCG2,SRP14-AS1,MAP4K4,PCYT1B,FAM149A,AKAP6,SUMF2,AHCTF1,IGDCC3,CPS1,TRIM69,RGS6,SEC24C,ARHGEF10,APPL1,GREB1,PUM1,CYBB,BOC,GAPVD1,DCAF8,ZFYVE16,ZNF337,DGKB,BRINP1,AIF1L,SPATA2,HEPH,KIAA0753,GUCD1,PLPPR4,PARD6A,SPOCK3,SEC16A,CPEB2,ACOT8,PDCD6IP,DTNA,ABCC5,EDN1,EDNRA,EDNRB,HEYL,PHF20L1,MRO,TMEM132E,EIF4G2,EMX2,EPB41,LRRC17,EZH1,F5,SH3YL1,TAOK3,DLC1,RACK1,FCGRT,FDFT1,KAT8,GORAB,BAIAP2,PRKAG2,POLK,SUCO,MEX3B,SYNCRIP,FLNC,HVCN1,TRIM16,NSG1,ABLIM2,GABBR1,DENND2A,GCK,ALDH1L1,ADAM28,GGT7,TCERG1,GLI2,TOX3,PCLO,GRIA2,GSTM5,ZBTB49,BVES,AP4S1,LINGO1,PSIP1,FAM107A,ADAMTS6,MAN1B1,MIER3,ELOVL5,HNMT,TCEAL6,LRRC75A,ICA1,ZIC5,KCNJ5,KTN1,STMN1,SYTL4,NCOA7,MAP2,MARK3,MBNL1,SHC3,PPM1L,BLOC1S2,MYCN,LYRM9,MYO7A,MYO9A,NEK1,NFYA,CNOT4,DNHD1,SLC11A2,NTRK2,NTRK3,IGSF11,GLIPR1L2,ETFRF1,ENPP2,SLC10A4,GPR85,PFKFB3,NALCN,FAM218A,NLE1,PCDH18,SMIM7,NECAB2,ING3,DRAM2,PPM1B,TATDN3,PPP2R2B,MAPK7,MAPK9,HYDIN,BCAS3,QRICH1,PIGG,PTCH1,BDNF-AS,STK32A,PTX3,ZSCAN2,ZNF615,TMEM231,TMEM255A,SLC25A48,FAM184A,RBBP6,MORC4,FIGN,ROBO1,CCDC25,PCMTD2,FBXW7,RPS6KA2,MAP6D1,HSD11B1L,CLIP1,TRAPPC13,ATXN7,SCP2,GALNT10,KIF21A,FERMT1,KIF16B,CPEB3,AMBRA1,R3HDM2,CNKSR2,CCDC92,ABLIM3,ARHGEF40,SLC12A4,BTBD7,SMARCD3,RCOR3,MYO16,ZSWIM8,SP4,TSPYL2,RBM26,DDN,LMO3,ITPRID2,SSTR2,ZSCAN29,CEP68,DIP2A,STAC2,ADHFE1,PRRC2C,TMEM150C,ARC,SYPL1,COBL,TACC1,TACR1,CAMTA1,PDLIM2,KLHL4,TCF4,ZFP90,ZEB1,TRIM2,USP32P1,TEK,SIRT1,AP4E1,BHLHB9,BEX4,PRRT1,TPM1,C9orf85,PPIL6,RUSC1,TSC1,HIRA,SGK3,FAM155A,PLEKHH2,ZNF709,MGAT5B,PLPPR2,CCDC136,WRN,CLDND1,XRCC4,LGI4,ZNF19,ZNF28,TRIM9,ZNF540,NDRG4,CRB2,MKRN3,ZNF138,CELF4,AMZ1,ZFAND5,STOX2,MDH1B,TRIM16L,DOCK8,HNRNPA3,ADAMTSL3,TIGD6,RNF170,MSRB3,JPH3" MicroRNA hsa-miR-145*:mirSVR_lowEffct hsa-miR-145*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-106 1.21E-102 5.18E-105 4.77E-104 278 1615 "ACADM,CLK4,C3orf14,EMILIN3,KLHL32,GALNT16,PSMG3-AS1,TMCC3,ADD2,ADORA1,PWWP2A,PTCHD1,BEND6,HACE1,NME5,WDR35,OSBPL8,ZNF578,ALCAM,FAM135A,ZNF687,OGT,CDC42BPA,ANK2,CCDC146,PARG,BCAS1,ATP1B3,DNAJC27-AS1,BID,BMPR1B,DST,SYNJ2,CASTOR3,WASF1,LDLRAD4,PTBP2,ISPD,SPAG9,PRC1,CBS,SEPT7,ZMYM4,LRRFIP1,LOC730101,DLGAP1,NOG,SRSF11,CHN1,CHN2,MS4A7,LHX2,NGEF,ABCG2,BAG4,HAPLN1,ANKRD44,GDA,SNCAIP,VCAN,PDE4DIP,PITPNM3,MYADM,ZNF337,DGKB,IP6K1,YTHDC1,HEPH,FBXL5,KIAA0753,ZC3H11A,SGSM2,DNAH9,CD99L2,DMTF1,DPH1,DRP2,PDCD6IP,RCAN1,ARRDC4,DTNA,FAM78B,E2F5,HIPK3,SEMA3D,FAM13A,MBNL2,GOLGA7,TENM1,C8orf37,ZNF549,SPEG,EZH1,CLVS1,TAOK3,DLC1,ZNF589,FECH,SEC24B,MED12L,OLFM1,FHL1,UBE2E3,MEX3B,SEC23B,FOXF2,JKAMP,TMEM107,APOPT1,STAMBP,TPK1,MEGF10,GABRB3,IP6K3,C15orf41,LRRC37A6P,GATM,ALDH1L1,CYP46A1,MSL3,ZNF638,ADGRA3,CCDC184,PRDM5,GRM8,FAM19A2,KAT7,ZBTB49,BVES,FAM107A,ADAMTS6,MAP4K5,ELOVL5,SYNPO,HNF4G,EID2B,MSL1,ZIC5,KIAA1755,SCIN,PAXBP1,NCOA7,MAP6,AQP11,KCTD6,MMP16,ADAM22,MYO5A,MYO6,NEXMIF,NF1,NINJ2,CNOT4,NTRK2,P2RY1,GPR137C,CNTN3,PDE4A,PDE4B,PDE4D,PDPK1,SERPINI1,KCTD15,SLC25A23,SMIM7,ING3,SEPT4,POU6F1,MINDY2,NKAIN4,MAPK4,DIRAS2,PRPSAP2,GDPD1,DCHS2,VPS13C,WBP1L,LAMA1,TMEM260,STK32A,ZIK1,PTPRB,PTPRN2,C1orf109,CEP97,SLC25A48,IQSEC3,REV3L,SLC25A36,PBRM1,RNASEL,CCDC82,ZNF532,YY1AP1,EPHA10,SPIN3,MCMBP,ATP8B4,ADAL,TCP11L1,ZNF354C,ATXN2,TNFRSF19,ZFP2,SUPT20H,ZFP30,SH3GL3,HKDC1,ST6GAL1,NLGN1,ARHGEF40,SLC12A2,SLC14A1,ZFP1,SMARCD3,SNAP25,MBD5,SNRPN,NMNAT2,GLT8D1,ZNF423,RBM26,NFASC,LHPP,ATP10B,PBLD,ZNF302,SSTR1,LARP4,ERBIN,STAC2,KANK1,RHBDL3,PLCB1,SYPL1,SYT1,EXOC7,PDLIM2,ADGRL3,TBCEL,ATMIN,NEU4,SATB2,TRIM2,SZT2,DOCK9,SIK3,RNF216P1,TMEM121,AP4E1,TMEM9,NPL,SYNPO2,METTL3,AMACR,TRO,TRPS1,TSC1,RPL7L1,UCHL1,UGT8,XRCC4,KCNT2,TRIM9,ZSCAN26,MFF,CADM2,SLC38A1,TMEM178A,FAM47E,MPPE1,DNAH10,PHTF2,CASC15,IFT88,ST8SIA2,PRRT4,FAM198A" MicroRNA hsa-miR-920:mirSVR_lowEffct hsa-miR-920:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-106 1.27E-102 5.39E-105 4.97E-104 304 1927 "VWA5B2,ASIC1,ACHE,AS3MT,SYS1,ACTN1,NDRG3,KLHL32,ADCY6,ADD1,PTCHD1,AP2A2,KIAA1324,C1QTNF1,PCDH10,LRFN1,ZFAT,OGT,FGD2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APAF1,AQP6,SFMBT2,SEMA4G,PRX,PCDHGB4,DPY19L3,ADAM15,ADGRB1,BBS2,DNAJC27-AS1,KSR1,CASTOR3,AP1M1,CFAP410,CA8,LURAP1,CALB2,HAP1,CAMK2A,ISPD,ZNF501,SLC16A4,CBFA2T2,DGKI,SRSF11,PLEKHB1,B4GALT6,TAOK2,PPT2,FBXO7,MAP4K4,ARMC8,CABP1,SUMF2,TOGARAM2,ANKRD44,CS,SNCAIP,CSF1R,SUSD5,VAC14-AS1,PLXNA4,KIAA0040,GREB1,MYADM,KATNAL2,HDAC4,MAML1,DGKB,DGKG,SCRN1,ZNF804A,SGSM2,SLC12A6,DPH1,RCAN1,DNAJB6,SNX29,FCF1,YAF2,APH1A,TMEM132E,AASS,COPS4,SRPK3,C3orf18,EPB41,EPB41L2,COQ7,EPHB1,STX2,VPS26C,RASL12,SIRPB1,CD320,MRVI1,PTK2B,RACK1,KAT8,GTF2IRD2,SPSB4,POLK,SUCO,ANKFY1,EFCAB2,AK8,PDLIM5,USP21,TRIM16,CELF1,NSG1,STAU2,AP4B1,ABLIM2,GHDC,CPLX2,GCK,ALDH1L1,SRCAP,TTBK1,HPGDS,RAB30,KDM2B,POLL,LILRB4,GPD1,GPD2,FUT10,GRB10,GRIA2,SPACA9,SERP2,BTN2A1,GSTM5,KAT7,GSTT2,ZBTB49,AP4S1,RABL2A,FAM107A,RNFT2,ATOH8,ZHX1,ATXN2L,ARHGAP36,ZDHHC15,SHISA6,C2orf72,LRRC25,INPP5B,KCNJ5,GATD1,CREG2,A1BG-AS1,L1CAM,TTYH2,STMN1,SFXN5,MAN2A2,MAP4,DBNL,SAMD5,MYO6,MYO7A,MYT1,FXYD7,NBL1,SFR1,NFE2L2,NNAT,NOVA1,SLC11A2,CLDN11,ZNF827,PCDHGC3,CDK18,NLGN3,PLCB2,PLIN1,FXYD1,PRIMPOL,ANKRD16,C19orf57,PPARA,TATDN3,NKAIN4,MAPK3,WBP1L,PIGG,PTCH1,TMEM260,STK32A,ZSCAN2,SLC25A48,ZNF793,SUSD4,RDX,GAL3ST4,TRIM68,PRRT2,RGS3,GSTCD,YY1AP1,SNX22,KIAA0895L,ATAT1,ZNF568,ZNF331,MAPK12,CSRNP3,PRCD,CASC3,R3HDM2,SYBU,ST8SIA1,SLA,SLC2A5,DHX30,KANSL3,SIRT2,SLC11A1,SMARCC2,MAPKBP1,SNCA,MBD5,SNRPN,RBM34,DOP1A,BDP1,TSNAXIP1,FNBP1,SOX15,SP2,KDM4C,PEG10,SPTAN1,CDK19,LMO3,ZSCAN29,APOM,RHBDL3,ARHGEF9,ADAMTS17,SYN1,FAM208A,ALG1,IQCE,FBXW11,MGRN1,NEU4,ZEB1,TPCN2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NAT16,SIK3,RNF216P1,DICER1-AS1,TIAM1,TMEM9,TLR4,ERCC6L2,FAM124A,PIK3R5,IL34,WBP2,TRPM2,TRPS1,TTTY15,SLC35A4,OSBP2,PLEKHH2,ZNF709,VIPR2,TBC1D15,CLIP2,KLC2,ZNF70,LYPD6,TMEM198,SLC30A4,DNALI1,SLC38A1,URM1,TRIM16L,PDSS2,RNF170,NETO1,AP3B2,LAS1L,FAM198A" MicroRNA hsa-miR-378c:mirSVR_lowEffct hsa-miR-378c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.92E-106 2.19E-102 9.28E-105 8.54E-104 301 1894 "CLK4,SYS1,KDM5D,CCDC85A,TMCC3,ADD2,ADORA1,ADORA2A,RNF150,PTCHD1,BEND6,MTA3,AP2A2,PCDH19,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,VAT1L,PPFIA3,CDC14B,SFMBT2,SPTBN4,ARNTL,MARK4,NUMB,N4BP2L1,DNAJC27-AS1,KSR1,GYG2,CACNA1G,RAB29,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,CAMK2G,VXN,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,SOCS6,MYL6B,ABCG2,QKI,CNGA3,FHL5,CNTN1,IQCK,FAM149A,AKAP6,COL4A5,ABI3BP,CLOCK,HAPLN1,CRYM,SNCAIP,VAC14-AS1,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,ARHGAP32,HDAC4,EARS2,INTS1,IST1,DGKG,SPATA2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLX1,RAB39B,DMTF1,SLC25A18,PDCD6IP,EDN1,HEYL,RASGRP1,SUGP2,IRAK4,PLEKHA1,MRNIP,TMEM35A,VPS13B,EPB41,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,CORO2B,CHST15,ZSCAN30,SEC24B,MED12L,SUCO,PCYOX1,AGAP3,PSD2,ZBED3,APOPT1,CHL1,GALC,RAPGEF6,IP6K3,INPP5K,SRCAP,GPR162,ADAM28,GGTA1P,TXNL4A,ZNF638,CBX1,DCLK2,CLASRP,BVES,IRAK3,SYNPO,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,IL6R,TMEM240,KCND1,KCNN3,L1CAM,HECTD2,MAT2A,AQP11,MEF2C,AFF1,MSR1,PTOV1,MXI1,MYO7A,RTL5,ZNF862,HNRNPM,NCF2,VWA2,NOVA1,DNHD1,NTRK3,PCDH9,PCSK1,CDK18,PDCD2,PDE4A,PDE1B,GPR173,TMOD2,PFKFB4,NLGN3,TMIE,ZNF655,CCSER2,XRN1,TMEM38A,PLCB2,SLC25A23,POU6F1,PPARA,PPM1B,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,WBP1L,CYBC1,PEX2,SUSD4,NWD1,RAP1GDS1,RASGRF1,GAL3ST4,ERI2,RGS3,PRIMA1,KCTD17,GSTCD,YY1AP1,PCMTD2,SNX22,RPL15,SPIN3,KIAA0895L,ATP8B4,GLDN,TCP11L1,ABCA11P,AP1AR,MAPK12,ATXN2,PEAR1,CASC3,ZNF821,SH3BP2,ANKRD6,EPN2,PKNOX2,ARHGEF40,BTBD7,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,SOX3,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SST,SSTR1,LARP4,ZSCAN29,APOM,SEPT8,ADHFE1,STX1A,ARHGEF9,SYN2,ANKRD28,MMS19,MCF2L,DNMBP,FBXW11,SIN3B,TCF12,NAT16,PCDHB9,TEK,FAM200B,ZNF34,AKTIP,SLC44A1,ARL10,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,ELP5,AMACR,DCBLD1,RUSC1,KCNE5,CLHC1,SLC35A4,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,ZNF24,KCNT2,LYPD6,ZBTB38,ANKS1B,SH3GLB2,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,PHTF2,FBXO36,FRMD6,FAM198A,JPH3" MicroRNA hsa-miR-548u:mirSVR_highEffct hsa-miR-548u:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.16E-106 2.33E-102 9.82E-105 9.05E-104 289 1749 "ACADM,NDRG3,ADD2,PWWP2A,KIAA1211,PTCHD1,ZNF608,MTUS1,KLHL13,KCTD16,KIAA1324,TAOK1,C1QTNF3,MARCH4,FAM135A,AMPH,OGT,APBA2,UPRT,CDC14B,TMEFF1,CDK13,MARK4,CHRD,SLC4A4,DPY19L3,ADGRB3,DST,SYNJ2,IL33,CACNB4,THSD7A,CALM1,RUNX1T1,C1orf52,LRBA,MAGI1,CCPG1,DIS3L,CHGB,CHN2,MS4A7,QKI,TMEM184B,ARHGEF6,CNR1,AKAP5,TBPL1,SEC31B,CDC42BPB,PREPL,CRY2,NCOR1,ABCG1,OSBPL3,CSNK1G3,SIPA1L1,RIMS4,PDE4DIP,CYBB,HDAC9,GAPVD1,RIPOR2,ZFYVE16,EARS2,IST1,DGKB,TMEM170A,TMEM130,ZC3H11A,PLPPR4,SACS,CHRDL1,DMD,NR1D2,DTNA,DNAJB6,EDNRA,ANKRD46,KLHL5,FRY,FSD1L,YAF2,PHF20L1,MBNL2,KMT5B,KCTD3,EIF4G2,EIF5,COPS4,PAN3,EPB41L2,EXTL2,EYA1,SCML2,CEP78,GORAB,SEC24B,OLFM1,FGFR1,PRKAG2,POLK,IP6K2,UFM1,ATP6V1H,KHDRBS3,ST6GALNAC3,STAU2,SARAF,OGA,FYB1,ERAP1,KIAA1841,GATM,IGSF5,WASHC2A,ADAM28,PPARGC1A,BRD8,GLI2,RAB30,GNAL,PRRC2B,PRUNE2,TDRKH,ZBTB49,MAP4K5,HAS2,HLF,IFI16,ZIC5,KCND2,CREG2,STXBP5,LAMA2,SMAD1,PIK3AP1,MARK1,MAT2A,MEF2C,POC1B,MITF,ZNF680,BLOC1S2,ZNF92,NCAM2,NEK1,NF1,NTRK2,CHAMP1,GPR137C,CNTN3,PCSK1,PDE4B,GNG2,NLGN3,PIK3C2A,ZNF655,FAM218A,SNX10,PMP22,STRN3,ING3,EPB41L4B,PKIA,MAPK9,GRAMD1C,VPS13C,QRICH1,WDR25,PIGG,CNTLN,PTCH1,ANKHD1,PTPRD,PTPRE,PTPRO,PPP2R3C,TMEM255A,USP47,FAM184A,RAP1GDS1,ENOX1,RADX,ERI2,GTDC1,RFX3,PNMA8A,RPE,TCP11L1,LRRK2,MEG3,CLIP1,RTN1,ZNF331,RMI1,SCN7A,SMPD3,SEC14L1,MRAS,ARX,SHC4,FBXO11,FNDC3A,R3HDM2,NLGN1,EPN2,KANSL3,ZNF430,SEPHS1,CCDC88A,ZNF667,COA1,KIF13A,SNRPN,USP33,BDP1,SP4,ZC3H13,SPART,ZC4H2,NKAIN2,ERBIN,NXT2,MPRIP,ZSCAN29,SEPT8,TTBK2,DIP2A,VPS13A,NUDT10,COBL,C12orf76,FAM208A,KIAA1107,TBCEL,FBXW11,ATMIN,DMXL2,CUX2,TRIM2,TCF12,SYNE1,DOCK9,PCDHB7,PUM2,USP32P1,SIRT1,AP4E1,MTMR14,TK2,NR2E1,ERCC6L2,C9orf85,METTL3,STXBP4,TSC1,TTTY15,SGK3,RPRM,FAM155A,PLEKHH2,CCDC14,WIPF1,NPDC1,ZIC2,ZNF17,ZNF19,KCNT2,FSTL5,DHX33,EMSY,PRTFDC1,ADAMTS9,NAV3,FIP1L1,RGS7BP,RTN4,PHTF2,ADAMTSL3,NHSL1,SNX14,FXR1,FRMD6,IFT88,NETO1,RNF146,GAN,LAS1L" MicroRNA hsa-miR-593*:mirSVR_lowEffct hsa-miR-593*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.18E-106 2.34E-102 9.83E-105 9.05E-104 290 1761 "ABCF1,ABR,ASPHD1,NCKAP5,KDM5D,XKR4,NDRG2,ADD1,AP2A2,FAM135A,ZNF687,CDC42BPA,EP400,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,FAM131A,CDC14B,TMEFF1,ZFYVE28,ARHGDIG,PDE8B,STK33,PCDHGB4,STX16,ATP2A2,SLC2A11,ADAM23,TTLL9,ADAM15,KSR1,CACNA1G,LDLRAD4,CA4,PTBP2,SPAG9,P2RX6,CD86,CACNA2D2,PLEKHB1,CNOT8,TAOK2,RAB33A,NRXN3,TPP1,CLTC,ARHGEF6,ANKRD35,SLC4A8,SMARCAL1,CREM,HINFP,SNCAIP,LRIG1,OSBPL3,RIMS4,ERC2,APPL1,HDAC9,MYADM,ARHGAP32,GAPVD1,TCAF1,DCAF8,DAPK1,IP6K1,ARMCX4,JAKMIP2,POM121,RHOBTB1,FAM107B,DYNC1I1,DPP6,ARRDC4,KRBA2,GOLT1B,SEZ6L2,FEM1B,CELSR3,KMT5B,TMEM132E,GOLGA7,KCTD3,EIF4G2,EIF5,IRAK4,TUBD1,COQ7,EPHB1,ERBB2,APC2,ETV1,REEP2,F8,SCML2,ZSCAN30,ZNF589,MED12L,FGFR1,MAD2L2,POLK,SUCO,MEX3B,FOXF2,SYNCRIP,NOP56,CELF1,ST6GALNAC3,DLL3,HHIPL1,GABRA3,ALDH1L1,CRCP,TNRC6A,MSL3,ADGRA3,PRUNE2,CCDC184,GPR37,TMEM121B,GRIK5,ZNF496,RNF165,KAT7,MAP4K5,RASSF8,TOX2,PADI2,FRMD5,MAN1B1,ELOVL5,HNMT,LRRC75A,GAREM2,LRRCC1,ITGA7,LINC00634,A1BG-AS1,LAMA2,STMN1,SMAD9,MAN2A2,ZFYVE27,MBD1,KITLG,MITF,COL28A1,COMMD5,MYO9A,RTL5,NEFM,NFE2L2,NFYA,VWA2,NTRK2,OCRL,OPRL1,PCDHGC3,CDK18,PDE1B,ENPP2,PDPK1,GNG2,PFKFB4,TMIE,PURG,SCHIP1,ING3,PRKAB2,MAPK9,PIGG,CNTLN,ELOVL2,SPDL1,PTPRO,QDPR,RAD51D,NWD1,HKR1,RGS3,ZFHX4,ALG9,CYB561D1,ROBO1,SNX22,NEK11,ATAT1,FAM192A,AP1AR,DGLUCY,SCP2,PEAR1,CASC3,GALNT10,MRAS,AMBRA1,DZIP1,SLC2A5,PEX26,SEPHS1,ARHGEF40,LGI3,SLC22A4,ZKSCAN3,INTS9,IFT122,INAVA,FAIM2,SNRPN,TMCC1,FAM126B,ZHX3,KDM4C,ERC1,NFASC,PBLD,SSPO,ZSCAN29,ELOVL4,STAC2,KANK1,JMJD6,ZC3H4,PRRC2C,RHBDL3,NUDT10,COBL,PDLIM2,ALG1,TCF4,SIN3B,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NAT16,DOCK9,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,PMS2CL,C18orf54,KAT6B,WBP2,ZNF346,SYNPO2,SMUG1,TRO,RUSC1,TSN,CLHC1,OSBP2,PLPPR2,VAV1,WRN,NPDC1,GUSBP1,ZNF28,TRIM9,ATP6V0E2,ZNF70,NDRG4,ZNF154,ZNF213,MEIS3,SLC30A3,ADAMTS9,HPS4,VPS35L,MDH1B,UBE3B,CASC15,FAM219B,TTC7A,NETO1,SENP7" MicroRNA hsa-miR-3166:mirSVR_lowEffct hsa-miR-3166:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.21E-106 2.35E-102 9.84E-105 9.06E-104 299 1870 "RALGAPA1,SYN3,ASIC1,AS3MT,ADCY6,RNF157,PWWP2A,PTCHD1,FAHD2CP,OLMALINC,MTA3,KIAA1324,TXNDC16,TAOK1,SEMA6A,SPOP,LTBP4,DOC2A,MYH7B,GAS7,PHYHD1,USP37,CDC14B,MADD,IGDCC4,ZFYVE28,ARHGDIA,ARSE,SLC4A4,ATP1B3,ATP2A2,RIPK1,ADAM15,BCL7A,CFLAR,BMP7,SCAPER,MYRF,THSD7A,CALM1,PTBP2,CAMK2A,CAMK2B,PRC1,ENTPD6,CDC25B,DCLK1,DIS3L,RCBTB2,SRSF11,CHRNA4,RAB33A,C4orf33,QKI,SRP14-AS1,ARHGEF6,CNR1,AKAP6,AKAP5,RTTN,MYRIP,CNRIP1,CLOCK,RBM39,ANKRD44,TRIM69,CSF1R,CSNK1G3,PDE4DIP,FAM169A,BOC,HDAC9,LONRF1,MATR3,DNAL1,ARMCX4,SPATA2,YTHDC1,C2CD2L,KLHL3,LYPD1,GSDME,DDX46,DLX1,GRIN3A,RAB39B,DNM1,SLC29A4,SLC12A6,PDCD6IP,MAMLD1,AASDH,CNNM1,HEYL,SEMA3D,PHF20L1,APH1A,AASS,RGS17,VPS13B,LRRC17,EPHB1,SLC43A2,DENND4A,SPEG,CDKL3,CLVS1,KAT8,ZNF589,SLC9B2,FGF11,FGFR1,AMOTL2,FLT1,TMEM107,GAD1,GHDC,INPP5K,KIAA1841,ALDH1L1,GGT7,GGT5,GHR,ZNF276,STARD3,MAP7D2,GNAO1,GPD1,GPD2,GRB10,DIDO1,GRM8,ZNF496,AP4S1,SOX21,FAM107A,ATOH8,HSPA1L,CELF5,MSL1,DISP2,ZNF678,SLC6A17,SLC35G1,KCND2,GPR62,STXBP5,LAMP2,HECTD2,PACRG,MARK3,MAT2A,MBD1,CHIC1,MEF2C,KCTD6,MID1,MN1,MT1M,MXI1,RTL5,HNRNPM,ZC3H12B,VWA2,NTRK2,OCRL,ZNF827,TREM2,PCSK1,PCSK5,PFKFB2,CCSER2,GPSM2,NLE1,PLCD1,PLXNB1,PNMA3,TRHDE,LRP12,SCHIP1,MAGEL2,EPB41L4B,PPM1B,PPP2R2B,LRRN3,PPP3CC,KANSL1,PPP5C,PRKAB2,PKIA,PRPSAP2,RELN,WBP1L,DEF8,CNTLN,MTMR10,PTPRE,PTPRG,NKAIN1,QDPR,NWD1,ENOX1,ZNF493,RBBP6,KHDRBS2,RET,GTDC1,KCTD17,PBRM1,ZFHX4,RNH1,TMLHE,C12orf49,ROBO2,ARMH4,TCP11L1,ATAT1,KCNIP3,TRAPPC13,SARS,ATXN2,ATXN7,SCN8A,PRCD,SCP2,FNIP1,CASC3,PPM1E,FERMT1,FNDC3A,NLGN1,SLA,SLC4A3,SLC9A5,SLC12A2,ATF7IP,SLC22A4,CDK5RAP2,RCOR3,ANKRD36,INAVA,SNAP25,SNRPN,TMCC1,DOP1A,SPTAN1,CDK19,DDN,CLSTN2,POGZ,SSPO,SEPT8,CEP68,SEPT3,STXBP1,VPS13A,SYT1,MLST8,TAL1,ADGRL3,FBXW11,DMXL2,TPCN2,NSD1,CCDC173,CYB561A3,PMS2CL,CDH22,THRA,TK2,RASD2,KCNE5,FAM155A,CLEC2L,PLEKHH2,WIPF1,CLDND1,GUSBP1,ZNF708,LYPD6,EML6,DPYSL5,ZFAND5,CADM2,DNALI1,SLC38A1,CIAPIN1,VPS35L,NAV3,MARCH8,UBE3B,PHTF2,CASC15,ACTR3B,RSPRY1,RNF170,ADAMTS10,SNX14,GAN" MicroRNA hsa-miR-3188:mirSVR_lowEffct hsa-miR-3188:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.31E-106 2.41E-102 9.99E-105 9.20E-104 283 1678 "KCNH8,NDRG3,KLHL32,ADD1,AXIN2,PLEKHH1,USP31,ESYT2,BEND6,HACE1,OSBPL1A,OSBPL8,ADGRF5,BBOX1,AMPD2,UPRT,CASK,CADPS,ZSCAN18,PCDHGB4,ZBTB10,ATP1B3,ATP2B2,RIPK1,TTLL9,LINC00847,BCL7A,NRP2,GPR146,SYNJ1,C5,BAIAP3,CFAP410,CA4,CA12,VXN,CAST,ZNF501,KYAT1,KRIT1,CERS5,RGN,CD86,ARHGEF2,PLEKHB1,EPS15L1,RAB28,STOML1,FAM189A2,FAM19A5,CNGA3,ARHGEF6,IQCK,ARMC8,AKAP6,CABP1,SMARCAL1,BAG4,TOGARAM2,MYRIP,ZNF521,ZNF385A,CREM,RBM39,AKAP12,ANKRD44,TRIM69,CS,CSNK1G3,PDE4DIP,CNTNAP2,ERC2,PLCXD3,CCDC144A,CYBB,KATNAL2,GAPVD1,ZNF337,RASSF2,TBC1D5,KCTD8,SCRN1,IP6K1,BRINP1,ELMSAN1,RUSC2,KLHL3,LYPD1,SGSM2,WDR20,FAM107B,EXOG,DMD,DOCK2,DRP2,DTNA,E2F5,EDN1,EDN3,EDNRA,EDNRB,SUGP2,EIF4G2,ING4,ELN,PAN3,EPB41L2,RCAN2,SRRM1,PIPOX,VPS26C,DNAJC27,KATNAL1,TMEM132C,FCGRT,SCARA3,SYNCRIP,IQCG,C2orf88,FAM49B,MEGF11,TRAF3IP2,GHDC,C15orf41,DISC1,ALDH1L1,GCNT2,SRCAP,ARFIP1,GGT7,GLI2,MSL3,GNAL,PRUNE2,FUT10,GPR12,STON1,GPR34,PRDM5,BVES,SOX21,ATOH8,FAM222A,ZHX1,HNMT,NEGR1,CPT1C,SCIN,KCNN3,KIFC3,IPO5,LIG4,MAN2A2,MBNL1,CHST6,MEIS2,AFF1,MOV10,COL28A1,PTOV1,MXI1,MYO6,MYO9A,MYT1,NOVA1,DNHD1,OPA1,OPRL1,P2RY1,PCDHGC3,CDK18,PFKFB3,RASGEF1B,MAPK10,DIRAS2,GDPD1,MASP1,NCR3LG1,ELOVL2,ZIK1,ZSCAN2,NKAIN1,MARCH1,RAD51D,RBBP6,ERI2,RFX3,RIC8B,SETD5,C12orf49,ARMC5,CARF,KIRREL1,SNX22,ARMH4,FBXW7,BAALC,ADAL,TCP11L1,MAP6D1,SEMA6D,LRFN5,TNFRSF19,CASC3,GALNT10,FAM102A,FERMT1,CHD9,FBXO11,FNDC3A,SEC31A,SLC6A11,SLC9A5,SLC12A4,MAST1,ANKFN1,RBM34,DOP1A,BDP1,KDM4C,PEG10,CDK19,RBM26,NFASC,ITPRID2,SSTR2,ZSCAN29,DIP2A,NECAB1,ARHGEF9,VPS13A,PLCB1,SYPL1,ANKRD12,ALG1,FBXW11,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NSD1,USP32P1,HIF3A,PMS2CL,ITGB3BP,TIAM1,CSMD1,TNS1,SYNPO2,TRO,STXBP4,TRPM2,CA14,SSBP2,PRR18,ZKSCAN5,TUBB1,GORASP1,UGT8,MGAT5B,WIPF1,ZIC1,ZNF45,ATP6V0E2,POLR3H,SPIRE1,DHX33,EMSY,DNALI1,PRDM10,SEMA3B,PPP1R3F,KAT6A,FAM219B,ADAMTSL3" MicroRNA hsa-miR-98:mirSVR_lowEffct hsa-miR-98:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.31E-106 2.41E-102 9.99E-105 9.20E-104 283 1678 "GALNT16,GALNT13,PLEKHH1,UNC5A,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,BEGAIN,CDC42BPA,LCORL,AQP6,CDC14B,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,ATP1B3,ATP2A2,SLC2A11,ADAM23,ADAM15,MPDZ,CACNB4,PTBP2,CAST,USP6,CD86,LRBA,LRRFIP1,L3MBTL4,CLGN,NUMBL,ASIC3,MS4A7,EPS15L1,TPP1,ABCG2,ARMC8,AKAP6,LETMD1,ABI3BP,SMARCAL1,RTTN,SEC31B,CRY2,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,DCAF4,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,ZBTB24,DDX46,POM121,SNAP91,TMCC2,GRIN3A,DOCK2,DMTF1,DPH1,ARRDC4,ECM2,SNX29,EDNRB,ANKRD46,YAF2,EBI3,EGR3,RASA4,GOLGA7,CERCAM,STARD3NL,VPS13B,EPB41L2,EPHB1,RABEPK,NCALD,KATNAL1,GMPR2,EZH1,ARMCX1,CORO2B,DLC1,CHST15,GTF2IRD2,FOXF2,IP6K2,FLT1,EFCAB2,HVCN1,UFM1,FAM49B,USP21,TPK1,CAMKK2,ATP6V1H,ZNF605,ERGIC3,SARAF,HRASLS5,DISC1,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,POLL,STON1,TMEM121B,SPACA9,RNF165,BVES,FICD,AP4S1,RABL2A,LINGO1,HAS2,HLF,HMGCL,SMAP1,FAM95B1,MYLK2,C2orf72,INPP5B,SLC35G1,KCND1,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,LRP1B,AFDN,ADAM22,MSR1,MYCN,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,P2RY1,CNTN3,PAX6,PCDH9,CDK18,PRTG,PFKFB3,TMIE,ZNF655,PLCB2,PURG,TRHDE,MAPKAP1,SCHIP1,RANBP3L,PRKACB,GRAMD1C,KLK6,BCAS3,LAMA1,DEF8,WDR25,PIGG,TMEM260,PTPRD,CASTOR1,PTPRG,TUG1,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,KCTD17,ZNF532,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,KIAA0895L,PTGR2,MEG3,TRAPPC13,ATXN2,PRCD,SEC14L1,CASC3,FOXRED1,HSPA4L,SH3BP2,CPEB3,ST6GAL1,WDR37,BTBD3,EPN2,FAM214B,ATF7IP,CPEB4,MAST1,MYH15,IFT122,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,TSPYL2,RBM26,DDN,POGZ,ITPRID2,PLCB1,PDLIM2,FBXW11,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,USP32P1,RNF216P1,AP4E1,ARL10,TIAM1,TK2,ERCC6L2,NPL,CHST5,RGMB,SMUG1,TRIO,STXBP4,TSC1,TTTY15,PRR18,CLHC1,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,PCDH20,ZNF28,ANKS1B,MEIS3,EVI5,TRIM16L,KAT6A,CASC15,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-936:mirSVR_lowEffct hsa-miR-936:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.65E-106 2.60E-102 1.07E-104 9.85E-104 286 1714 "ABR,ASPHD1,ACADM,ASIC1,NDRG3,TMEM132B,TMCC3,AXIN2,ADRA1D,MTUS1,KLHL13,RTL9,OSBPL1A,HFM1,DPP10,ANK2,CCDC146,APBA2,MAGEE2,UPRT,USP37,CDC14B,MADD,ZFYVE28,NUMB,TTLL9,BBS2,KSR1,FUBP1,SCAPER,CACNA1G,C5,GPC2,IL33,KALRN,CAMK2A,CAPN3,CBFA2T2,C1orf52,LRBA,LRRFIP1,LOC730101,DLGAP1,MS4A7,SRP14-AS1,MAP4K4,ARHGEF6,PCYT1B,ARMC8,COL4A5,ABI3BP,MYRIP,ZFP28,CNRIP1,SNCAIP,OSBPL3,CST3,APPL1,PHF14,CTH,DCAF4,CCDC144A,KATNAL2,GIT2,PITPNC1,ARMCX2,DGCR5,ZC3H11A,PLPPR4,SEC16A,DMD,NR1D2,DRP2,DTNA,DNAJB6,SEZ6L2,HEYL,SUGP2,MRO,EIF4G2,EPB41L2,EPHB1,GPHN,STX2,CEP85L,ETV1,SIRPB1,EXTL2,EYA1,HSPA12B,FAM198B,ST3GAL6,ZSCAN30,ZNF589,GORAB,FER,FGF1,SPSB4,FGF13,FGF14,FHL1,POLK,UBE2E3,PCYOX1,SEMA4D,FLT1,PSD2,EFCAB2,TMEM107,HVCN1,UFM1,ATP2C1,ERGIC3,HRASLS5,GALNT15,GABRG1,GALC,RAPGEF6,ERAP1,ACSS1,KIAA1841,GATM,NEU3,GCNT2,TUBGCP4,SULT1C4,LYVE1,MAP7D2,LUZP2,FERMT2,STON1,LPAR4,GPR37,GRIN2C,ZNF496,KAT7,AP4S1,RASSF8,TNFAIP8L3,C9orf129,ZDHHC15,NEGR1,DHX35,IGF1,RBPJ,TJAP1,KCNJ5,A1BG-AS1,STMN1,PAXBP1,SYTL4,SMAD1,MARK1,MATN3,MEIS2,XRRA1,MMP16,ADAM22,MX1,RTL5,DNHD1,NPTX1,SMIM11A,NTRK2,CLDN11,P2RX7,PAX6,SLC10A4,GNG2,PFKFB3,PIK3C2A,PIK3R1,ZNF655,CCSER2,PLEC,PCDH18,SMIM7,PURG,PDZRN4,TRHDE,POLG,KANSL1,PRKCB,MAPK9,RELN,CNNM2,BCAS3,VPS13C,APTX,PTCH1,MTMR10,PTN,PTPRB,PTPRG,NKAIN1,TUG1,ZNF844,PPP2R3C,ZNF793,FAT4,KHDRBS2,RDX,ZMAT4,RET,SLC25A36,ROBO2,RORB,SPIN3,ZC3H14,LRRK2,ABCA11P,ATAT1,FAM192A,SAFB,SARS,ATXN2,ATXN7,LRFN5,SCN8A,SCP2,COPZ1,KIF16B,MYO18A,FNDC3A,DZIP1,ANKRD6,FAM81A,SLC6A8,ELMO2,CDK5RAP2,ANKRD36,MAPKBP1,MBD5,DOK5,KDM3A,ZBTB43,THSD1,KANK1,PLCB1,SYT1,FBXW11,TPCN2,SZT2,SYNE1,PCDHB3,TNS2,GPRIN3,ZFPM2,C18orf54,TIAM1,NACC2,TMPO,FAM124A,RIMBP2,SYNPO2,STXBP4,TRPS1,TSN,TTTY15,UCHL1,UGT8,USP1,BCL2L13,VLDLR,LMF1,VSNL1,ZNF711,ZNF24,ELFN1,ZNF74,LYPD6,ZNF138,FSTL5,DHX33,RNF103,NAV3,FAM47E,RGS7BP,AMN1,UBE3B,HNRNPA3,PHTF2,CASC15,FXR1,DPF3,CPNE4" MicroRNA hsa-miR-101*:mirSVR_lowEffct hsa-miR-101*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.65E-106 2.60E-102 1.07E-104 9.85E-104 286 1714 "ACADM,SYS1,PWWP2A,KIAA1211,INTS2,HECW2,CASKIN1,OSBPL1A,OSBPL6,AK2,SPARCL1,PCDH10,EP400,C6orf89,CCDC146,PPP4R4,ZNF583,RNF182,BACH1,MPDZ,SYNJ1,FUBP1,NAE1,SGCE,WASF1,RHBDL1,RUNX1T1,CLDN10,USP2,MTMR7,CD38,LRBA,DCLK1,LRRFIP1,SRSF11,B4GALT6,CNOT8,NRXN3,FAM19A5,C4orf33,MAP4K4,ARHGEF6,CNTN1,CABP1,RTTN,SLC35F1,FAM171B,SEC31B,CLOCK,ENTPD4,CRHBP,HAPLN1,GDA,SNCAIP,CSF2RA,OSBPL3,VCAN,PHACTR3,DZIP3,CTH,CCDC144A,HDAC9,PITPNC1,ZNF804A,ZBTB24,TIAM2,MFAP3L,ARRDC4,DNAJB6,FARSB,E2F5,EDIL3,CNNM1,KLHL5,FAM13A,MRO,RASA4,GOLGA7,PLEKHA1,RGS17,USPL1,LRRC17,GPHN,IGSF6,RRAGB,F5,ST3GAL6,FCGR1B,FKTN,POLK,PCYOX1,SYNCRIP,EFCAB2,STAMBP,ST6GALNAC3,STAU2,MSANTD4,OGA,ZMAT1,GABRA3,GABRG1,TRAF3IP2,RAPGEF6,ZNF274,DISC1,KIAA1841,GATM,MSTN,SESN1,ADAM28,GHR,PPARGC1A,MALT1,RAB30,LUZP2,GNAL,GPD2,STON1,GPR34,PCLO,CNTRL,DIDO1,PRDM5,BVES,HAS2,PADI2,ZHX1,ATXN2L,HNMT,CELF5,MSL1,LRRCC1,TJAP1,IL12A,INSM1,KCNH2,LIMS1,PAXBP1,LYPLAL1,MARK3,SRSF12,MIA2,MID1,COL28A1,LYRM9,MYT1,NDP,NFYA,NOVA1,CNTN3,ETFRF1,PCDH8,PCDH9,PRTG,GPR85,PFKFB2,PIK3R1,ZNF655,PCDH18,MTRF1L,PURG,PRIMPOL,PDZRN4,PMP22,PPM1B,LRRN3,RANBP3L,MAPK4,HYDIN,PRPSAP2,CNTLN,BDNF-AS,PTN,PTPN13,PTPRD,PTPRE,TUG1,MARCH1,RAP1GDS1,OXR1,RADX,KHDRBS2,ZMAT4,NUDT11,ZNF532,RPE,GLDN,RTN1,RXRA,ZNF331,CSRNP3,SCP2,FNIP1,KIF27,RASA3,CPEB3,CHD9,FBXO11,FHOD3,NLGN1,ANKRD6,NUBPL,FAM81A,SLC12A2,CPEB4,RCOR3,ANKRD36,LIMCH1,SNAP25,MBD5,PDZRN3,MYO16,PDZD2,KDM3A,SP4,NMNAT2,MYCBP2,SPP1,KDM4C,ERC1,PEG10,ARHGAP26,TSPYL2,RBM26,PBLD,SST,SEPT8,ADHFE1,SULF2,PRRC2C,SLC37A2,ANKRD12,MTCL1,ADGRL3,AGTPBP1,KLHL4,SATB2,TPCN2,RPGRIP1L,PCDHB9,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,ZFPM2,ITGB3BP,BHLHB9,ERCC6L2,FAM124A,R3HDM1,WBP2,RGMB,SYNPO2,PDSS1,STXBP4,TRPS1,TUBB1,WRN,RICTOR,PCDH20,KCNT2,ZBTB38,FSTL5,ZSCAN26,UPF3A,EMSY,CADM2,PRTFDC1,HPS4,EPM2A,FAM13C,AMN1,FZD3,CASC15,ZDHHC20,IFT88,ZNF30,CPNE4,SENP7" MicroRNA hsa-miR-924:mirSVR_lowEffct hsa-miR-924:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-106 3.07E-102 1.26E-104 1.16E-103 287 1727 "RALGAPA1,ABR,ACADM,AS3MT,NCKAP5,SYS1,KLHL32,PLEKHH1,SLC24A4,CC2D2A,ALCAM,SRPX,FAM135A,CDC42BPA,FGD2,PHF12,APC,CDC14B,PPP4R4,TMEFF1,CDK13,ATP1A1,EIF4G3,ATP1B3,SLC2A11,MPDZ,LDHD,BMP7,BMPR1B,ST3GAL5,SCAPER,GPC2,WASF1,LDLRAD4,CA8,CA12,CACNB4,KALRN,CAMK2G,VXN,CH25H,KRIT1,SLC16A4,CBFA2T2,DGKI,SRSF11,ASIC3,SLIT2,TPP1,QKI,MAP4K4,ARHGEF6,CNTN1,COL4A5,SLC4A8,TBPL1,AHCTF1,ZNF521,C2CD2,NCOR2,CS,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,UBXN2A,PHF14,ZSCAN23,SEC14L5,BOC,KATNAL2,TBC1D5,ARMCX4,ARMCX2,ZBTB24,MFAP3L,DDX46,TMCC2,FAM107B,DLX1,ACOT8,DNM1L,EDN1,EDNRB,APH1A,EGR3,IRAK4,STARD3NL,EPB41,RCAN2,LRRC17,RASGRP2,GPHN,ERBB2,IGSF6,KATNAL1,ARMCX1,CLVS1,ST3GAL6,ZSCAN30,GTF2IRD2,FGF13,BAIAP2,PRKAG2,FOXO3,ATP13A4,SYT3,JKAMP,POMT1,TMEM107,FAM49B,KHDRBS3,CELF1,STAU2,AP4B1,OGA,ERAP1,ZNF559,C15orf41,KIAA1841,SULT1C4,MSTN,CYP46A1,PPARGC1A,GNAO1,FERMT2,TDRKH,PCLO,GRIN2C,BVES,SOX21,ADAMTS6,GUCY1B1,RASSF8,TNFAIP8L3,ARHGAP36,HNMT,CPT1C,LRRC75A,SHISA6,IGF1,ZIC5,RBPJ,LRRCC1,IL6R,KCNB1,KCNF1,KCNN2,LAMA2,LIMS1,HECTD2,PIK3AP1,ZFYVE27,MAP2,MARK1,MAT2A,LRP1B,SHC3,XRRA1,TAGLN3,NEXMIF,P2RY13,CCDC13,NFE2L2,NOVA1,DNHD1,SMIM11A,NTRK2,OCRL,P2RY1,GLIPR1L2,PDCD2,PDE4A,GPR85,ZFYVE21,RETREG1,XRN1,JAKMIP1,PCDH18,ANKRD16,DRAM2,PPP2R5E,KANSL1,RASGEF1B,PRKACB,MAPK9,GRAMD1C,TMEM104,TMEM260,PTPRB,PTX3,TUG1,TMEM231,ACSS3,CCDC40,FAT4,ROGDI,KHDRBS2,MSANTD2,ZMAT4,RGS4,PBRM1,TMLHE,GLDN,SGSM1,ATAT1,ATXN2,SCN7A,SCP2,TNFRSF19,SEC14L1,SUPT20H,PPP4R3A,SEPHS1,ARHGEF40,SLC14A1,BTBD7,ZNF667,MYH15,ANKRD36,SNRPN,DOP1A,SOX11,UHRF1BP1L,ZNF423,TSPYL2,NFASC,ZNF621,ATP10B,PBLD,CLASP2,NXT2,SEPT8,STXBP1,PLCB1,SYT1,CAMTA1,FAM208A,KIAA1107,ATMIN,RPGRIP1L,FAM189A1,SLC19A3,PCDHB4,FRYL,HIF3A,CYB561A3,DNAH7,PMS2CL,ITGB3BP,HEY1,ACTR6,BHLHB9,FAM124A,TP53BP2,CHST5,ZNF346,SYNPO2,SMUG1,TSC1,SSBP2,TTTY15,TUBB1,UBE2H,MTCH1,RICTOR,GUSBP1,LGI4,ZNF19,ZNF24,MICU3,KCNT2,ELFN1,MKRN3,CELF4,EMSY,PRTFDC1,LINC02210,STOX2,RNF103,SLC17A7,FIP1L1,HRASLS,ST7,SNX14,RNF146,LAS1L" MicroRNA hsa-miR-1911*:mirSVR_lowEffct hsa-miR-1911*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.28E-106 3.51E-102 1.43E-104 1.32E-103 271 1541 "RALGAPA1,DGCR6,CLK4,C3orf14,METAP1D,TMEM132B,ADCY6,ADD1,ADD2,BRAP,KIAA1211,BEND6,KIAA1324,SEMA6A,USP35,CARNS1,AMPD2,CDC42BPA,PHF12,SUGT1P4-STRA6LP-CCDC180,APBB2,PPFIA3,SHROOM2,PDE8B,PCDHGB4,ZBTB10,NCOA1,NUMB,N4BP2L1,DPY19L3,DOCK11,TTLL9,ADAM15,MPDZ,RGS9,CFLAR,FUBP1,RAB29,MYRF,CACNA1B,DDR1,VXN,PRC1,CERS5,RGN,CBFA2T2,ENTPD6,ARHGEF2,L3MBTL4,MAGI1,SRSF11,SULT4A1,SRP14-AS1,COL9A1,AKAP5,ZFP28,IGDCC3,ZNF385A,CRY2,ANKRD44,TRIM69,CS,SEC24C,UBXN2A,CTH,PUM1,RIMS2,PPP6R2,GAPVD1,RIPOR2,DCAF8,IP6K1,KIAA0753,RUSC2,C2CD2L,DDX46,RHOBTB1,SGSM2,GRIN3A,DNM1,SLC29A4,DMTF1,DPP6,ECM2,DNM1L,CNNM1,HEYL,ASB3,EIF4G2,LRRC17,ENPP6,ETV1,EYA1,PTK2B,FCGRT,FGF11,FGFR1,IP6K2,ATP13A4,FLT1,TMEM175,SMC2,HVCN1,TPK1,ZNF605,GALNT15,GABRG2,SIGLEC8,INPP5K,KIAA1841,ALDH1L1,GCNT2,GPR162,GGTA1P,PPARGC1A,BRD8,SPIN1,GLI2,DCLK2,GNG4,GPER1,SPACA9,ADAMTS13,CLASRP,RNFT2,ATOH8,FAM222A,MUM1,RASSF8,PADI2,HLF,HNMT,ZNF491,TCEAL6,EID2B,IDH3A,IDH3B,IL6R,METTL21A,GPR62,NCOA7,MBD1,LRP1B,KITLG,AFF1,MPP2,MSR1,N6AMT1,NEXMIF,ALDH1L2,CNOT4,PCBP3,NTRK3,CLDN11,P2RX7,GLIPR1L2,PALM,ETFRF1,PCDHGC3,PCSK1,PDE4D,ZDHHC8,NALCN,SLC25A23,ANKRD16,PDZRN4,STRN3,ING3,SEPT4,FSD1,PPARA,KANSL1,PRKACB,CEP41,PRKCB,PRODH,PTPRE,CASTOR1,PTPRH,PID1,ACSS3,FAM66C,NWD1,HKR1,KHDRBS2,ZMAT4,ERI2,UBR7,ARMC5,ROBO1,BAALC,ST6GALNAC6,DGLUCY,ATXN7,CASC3,GALNT10,MRAS,SUPT20H,TRA2B,COPZ1,SGK1,KIF16B,ASAP3,AMBRA1,WDR37,PEX26,PPP4R3A,FAM214B,SEPHS1,LGI3,SMARCA4,IFT122,MAPKBP1,MBD5,KIF13A,KDM4B,USP33,IZUMO4,PEG10,IQSEC2,TSPYL2,SSTR1,SEPT8,RGL1,ADHFE1,KANK1,SUPT5H,VPS13A,SYN2,C12orf76,TACR1,ANKRD12,PJA1,TAL1,ALG1,ADGRL3,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PHF24,PUM2,HIF3A,RNF216P1,ZFPM2,PIK3R5,ZNF346,TRIO,AMACR,UBE2H,BCL2L13,ATP6V0E2,NDRG4,SPIRE1,ZFAND5,RNF103,ADAMTS9,TRIM16L,GJC2,CASC15,FRMD6,SOCS4" MicroRNA hsa-miR-26a:mirSVR_highEffct hsa-miR-26a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.44E-106 3.60E-102 1.46E-104 1.35E-103 265 1473 "ACADM,CLK4,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HACE1,TXNDC16,SMIM17,ALCAM,LRCH2,EP400,APAF1,APC,TNRC6C,RGS20,CDK13,CCDC74A,SLC4A4,ATP1B3,LINC00847,BID,GPR146,BMPR1B,DST,ST3GAL5,FUBP1,SCAPER,JAZF1,KALRN,VXN,KRIT1,USP6,LARGE1,CFL2,SRSF11,SOCS6,CHN2,MS4A7,CLCN3,CLTC,QKI,TMEM184B,CNR1,AKAP7,COL4A5,BAG4,SLC35F1,CLOCK,C2CD2,RBM39,HAPLN1,GDA,ARHGEF10,PLXNA4,DZIP3,ERC2,GREB1,RUBCN,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,KCTD8,DAPK1,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,PLPPR4,SACS,WDR20,EXOG,GRIN3A,DMD,USP3,DPYSL2,PDCD6IP,DTNA,FCF1,TMTC1,FSD1L,EGFR,EIF4G2,EIF5,TENM1,CALCRL,PAN3,LRRC17,EPHB1,STX2,ETV1,RPS6KC1,TMEM132C,GORAB,FGF14,MEX3B,IP6K2,SEMA4D,NOP56,UFM1,NEURL4,ZNF44,ACSS1,TUBGCP4,SRCAP,PPARGC1A,TNRC6A,ZNF638,KCNMB4,GNAL,GRB10,DIDO1,CLASRP,LINGO1,ADAMTS6,UBE2QL1,ZHX1,ATXN2L,MIER3,HNF4G,CELF5,MSL1,ZIC5,IL6ST,FAM69A,JAK2,KCND2,STXBP5,KTN1,LAMP2,SMAD1,MAP2,MARK1,MAT2A,MATN2,MITF,AFDN,MMP16,ZNF680,BLOC1S2,ZNF92,MXI1,MYO9A,NEK1,CNOT4,SLC11A2,GPR137C,PCDH8,PCDH9,SLC10A4,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,PLCL1,PCDH18,PURG,ING3,RETREG2,FA2H,MINDY2,PPM1B,RANBP3L,CEP41,MAPK10,GRAMD1C,HYDIN,VPS13C,PIGG,STK32A,ZSCAN32,PTPN13,PTPRD,TTC13,ZNF615,PPP2R3C,CEP97,TMEM255A,ZCWPW1,ERI2,UBR7,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,GSTCD,ARMH4,GLDN,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,GALNT10,MRAS,KIF27,CHD9,FBXO11,NLGN1,ZNF430,CCDC88A,TET1,CPEB4,MYH15,ANKRD36,LIMCH1,CMTR2,TMCC1,USP33,ZC3H13,CLASP2,TROVE2,LARP4,STAC2,NECAB1,SYNE2,NUDT10,PLCB1,ANKRD28,PJA1,DNMBP,FAM208A,KLHL4,TCEA1,USP32P1,FRYL,FAM200B,AP4E1,ERCC6L2,FAM124A,AMACR,STXBP4,PPIL6,DCBLD1,TSN,ANKRD20A2,TTC3,ZKSCAN5,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,KCNT2,MKRN3,ZBTB38,ANKS1B,EMSY,CIAPIN1,MDH1B,MPPE1,WNK3,PDSS2,CASC15,JMJD1C,RNF170,NHSL1" MicroRNA hsa-miR-3155:mirSVR_lowEffct hsa-miR-3155:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-105 5.95E-102 2.41E-104 2.22E-103 308 1988 "ABCF1,ABR,SYS1,KDM5D,CCDC85A,ADD1,ADD2,AXIN2,ADORA1,KIAA1211,BEND6,ZNF608,OSBPL1A,OSBPL8,ALCAM,SRPX,FAM135A,SYT13,ZNF687,AMPD2,AMPD3,ZFAT,UPRT,BCAS1,TNRC6C,PPFIA3,CPNE5,LGR5,SHROOM2,SPTBN4,CADPS,CCAR2,ATP1B3,STX16,SLC2A11,RNF182,ADAM23,RGS9,NRP2,CFLAR,KSR1,SYNJ2,ARHGEF7,NAE1,BTK,C5,GPC2,WASF1,CACNA1B,CALM1,KALRN,CAMK2B,SPAG9,KRIT1,METTL6,CD86,CDC25B,ZBED1,TIGD7,CFL2,RCBTB2,PLEKHB1,NDST3,RAB28,CLCN3,IGLON5,CNTFR,IQCK,COL11A2,SLC4A8,BAG4,MYRIP,IGDCC3,AKAP12,HINFP,CSF1R,SEC24C,SUSD5,CST3,PPP1R16B,ARHGAP32,GAPVD1,LIN54,MAML1,IP6K1,PABPC5,GIT2,PITPNC1,HEPH,C2CD2L,TMEM130,SGSM2,WDR20,EXOG,HS3ST2,DNAH9,SLC29A4,SHANK1,DPP6,PDCD6IP,DTNA,EDN3,PHC2,FCF1,CNNM1,FAM13A,PHF20L1,EGR3,GOLGA7,TENM1,TNK2,MRNIP,C3orf18,ENO2,EPB41L2,COQ7,ENPP6,MRPL10,TLR7,HSPA12B,NRN1,FAM198B,TBC1D16,ZNF589,GTF2IRD2,SCARA3,UBE2E3,AGAP2,SEMA4D,MEGF10,GALNT15,ZNF234,DISC1,INPP5K,GCNT2,ARFIP1,GDF9,SESN1,GFER,GHR,TXNL4A,MSL3,DCLK2,GPD2,MCHR1,TMEM121B,GRB10,PLPP7,ADAMTS13,GRIN2C,PRDM5,SOX21,GUCY1B1,TOX2,NXPH3,MAN1B1,MSL1,GAREM2,ZIC5,TJAP1,INPP5B,GATD1,KHK,KIF5A,A1BG-AS1,LAMP2,STMN1,NCOA7,MAP4,MARK1,MAT2A,MEIS1,POC1B,AFDN,MMP16,DBNL,SAMD5,MYCN,MYO7A,HNRNPM,NF1,NOVA1,OGG1,P2RX7,P2RY1,PALM,PCSK5,PFKFB3,SEMA5B,TMIE,CCSER2,ZFYVE21,ANKRD16,PMP22,SDK2,SEPT4,FSD1,PPP1R1A,NKAIN4,CEP41,EPDR1,HYDIN,GDPD1,WBP1L,ANKHD1,PTPRH,MARCH1,ACSS3,RAD17,CCDC40,RAD51D,SUSD4,NWD1,RAP1GDS1,RET,PRRT2,ERI2,RFX3,RIC8B,C12orf49,CYB561D1,KIRREL1,CCDC102B,KIAA0895L,ADAL,MAP6D1,ATAT1,DGLUCY,SARS,SEMA6D,FNIP1,CASC3,FOXRED1,ASAP3,SHC4,CHD9,FBXO11,FNDC3A,ST6GAL1,NUBPL,ARHGEF40,SLC9A5,SLC11A1,ELMO2,ATF7IP,ABTB1,MAPKBP1,USP33,PDZD2,TSNAXIP1,SPP1,DBNDD2,NFASC,LHPP,TROVE2,POGZ,ITPRID2,ZC4H2,ZSCAN29,NEK4,STXBP1,SUPT5H,PRRC2C,ARHGEF9,SYPL1,COBL,MGRN1,TRIM2,SYNE1,NAT16,SLC19A3,HIF3A,RNF216P1,DICER1-AS1,CDH22,ARL10,THRA,TIMP4,ACTR6,C9orf85,SMUG1,TRPS1,TTTY15,ZKSCAN5,RPL7L1,UBE2H,LINC00689,PLEKHH2,VLDLR,WIPF1,LAT2,GUSBP1,ZIC1,NDRG4,TMEM237,ZNF177,POLR3H,ZNF213,ZXDA,PRDM10,RNF103,HPS4,EPM2A,KAT6A,HNRNPA3,FBXO36,TRAM2-AS1,PRRT4" MicroRNA hsa-miR-4284:mirSVR_lowEffct hsa-miR-4284:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-105 5.99E-102 2.41E-104 2.22E-103 296 1840 "XKR4,ESYT2,AP2A1,AP2A2,INTS2,ZNF578,TAOK1,SMIM17,SRPX,MARCH4,PCDH10,AMPD2,DPP10,FGD2,CCDC146,MYH7B,PKP4,APBA2,BCAS1,USP37,LGR5,CDK10,SFMBT2,TMEFF1,ZSCAN18,NCOA1,TMEM108,ALDH7A1,ATP6V0A1,ADAM15,BBS2,NRP2,KSR1,BMP7,ARHGEF7,WASF1,CALB1,KALRN,PTBP2,CAMK2B,CAMK2G,SLC25A14,ISPD,KRIT1,METTL6,ZBED1,LRRFIP1,LOC730101,LARGE1,MAGI1,DIS3L,SRSF11,PLEKHB1,MS4A7,NDST3,CLCN3,CLTC,SUMF2,ABI3BP,SMARCAL1,SEC31B,ENTPD4,RBM39,GDA,AATK,SEC24C,SUSD5,SOCS5,KIAA0040,CTH,DCAF4,RUBCN,GAPVD1,TCAF1,RIPOR2,CENPL,MFAP3L,KLHL3,DDX46,GUCD1,PLPPR4,SPOCK3,RAB39B,DNM1,RPS6KL1,MED12,CDON,DOCK2,PDCD6IP,MAMLD1,KRBA2,EBF1,EDNRA,SEMA3D,KLHL5,OPTN,PHF20L1,EIF5,IRAK4,COPS4,MRNIP,C8orf37,VPS13B,COQ7,RABEPK,SLC43A2,NCALD,ETV1,VPS26C,ANKMY1,TBC1D16,SCML2,RACK1,POLR1B,FGF11,POLK,IP6K2,PCYOX1,FOXO3,FLT1,SLC37A3,EFCAB2,TRIM16,TVP23A,ZNF44,GABRB3,DENND2A,GALC,TMEM8B,SEPT9,INPP5K,KIAA1841,SRCAP,SESN1,GFER,NTNG2,BRD8,ZNF276,TXNL4A,CRCP,TCERG1,DBF4,RAB30,TNRC6A,KDM2B,LUZP2,CCDC184,PLCD4,SPACA9,ADAMTS13,GRM8,AP4S1,RASSF8,PADI2,MAN1B1,BACH2,HSF2,MYLK2,ZNF546,SCIN,KCNJ5,GATD1,LIMS1,SYTL4,NCOA7,MARK1,MEIS1,AFDN,MT1M,MXI1,LYRM9,MYO6,HNRNPM,NEFM,VWA2,SLC11A2,SMIM11A,NUCB2,CLDN11,P2RX7,PALM,GNG2,PFKFB3,OLA1,ZDHHC8,ANKRD16,LRP12,MBOAT7,PILRA,NKAIN4,PRKACB,PRPH,PTPRB,C1orf109,CCDC40,ZNF793,NWD1,ZNF493,ZMAT4,RGS12,PRIMA1,PBRM1,ARMC5,CARF,GSTCD,ROBO1,ROBO2,CCDC25,CCDC102B,RPL15,GLDN,ADAL,ZNF331,DGLUCY,GALNT10,MRAS,FBXO11,ABLIM3,PEX26,KANSL3,SLC6A8,CCDC88A,SLC11A1,SLC12A2,INTS9,INAVA,SNCA,SNRPN,FAM126B,KDM4B,USP33,PDZD2,SP2,MYCBP2,KDM4C,TEX2,UNC5B,SPTAN1,LMO3,POGZ,ZSCAN29,NEK4,STAC2,SEPT3,JMJD6,ADAMTS17,ANKRD28,CAMTA1,EXOC7,TAL1,MGRN1,SYNE1,TNS2,RNF216P1,FAM200B,DICER1-AS1,AP4E1,ZNF106,SLC44A1,NR2E1,ERCC6L2,KAT6B,TP53BP1,CDK20,C9orf85,ZNF346,ELP5,NEIL2,PLEKHH2,BCL2L13,TBC1D15,P2RY12,LAT2,RICTOR,PCDH20,ZNF708,ZNF74,TMEM237,EML6,DPYSL5,PCBP1-AS1,SLC30A3,SLC30A4,ZXDA,EMSY,LINC02210,RNF103,HPS4,SIGLEC10,FIP1L1,MPPE1,KAT6A,FBXO36,JMJD1C,TIGD6,JPH3" MicroRNA hsa-miR-487a:mirSVR_lowEffct hsa-miR-487a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-105 8.47E-102 3.40E-104 3.13E-103 280 1651 "KCNH8,ACADM,SYS1,FMNL2,PSMG3-AS1,PLEKHH1,RNF150,KCTD16,OSBPL1A,KIAA1324,SPARCL1,ALCAM,FAM135A,AMPD3,AMT,DPP10,LRCH2,MAP4K3,APAF1,APC,SHROOM2,CASK,ARNTL,CADPS,NCOA1,TMEM108,ATP2A2,DPY19L3,ADGRB3,MIR9-3HG,DST,SCAPER,MTMR2,IL33,CACNB4,KALRN,SLC25A14,PRC1,MTMR7,SLC16A4,SEPT7,CDO1,FOXN3,CHN2,B4GALT6,NDST3,RAB33A,NRXN3,CLCN3,C4orf33,QKI,AKAP7,AKAP6,COL4A5,LETMD1,ABI3BP,ZNF521,CLOCK,PDE4DIP,PUM1,ZSCAN23,CCDC144A,KIAA0408,GPRASP1,ARHGAP32,RIPOR2,ZNF337,MAML1,HEPH,KIAA0753,DDX46,ALKBH8,SNAP91,ZNF582-AS1,CHRDL1,DLX1,DMTF1,ECM2,EDNRB,SEMA3D,OPTN,MBNL2,EGR3,ASB3,EIF4G2,TENM1,EPB41L2,DENND4A,CEP85L,ETV1,NRN1,CLVS1,NSRP1,ZNF585B,RPS6KC1,ZSCAN30,FDFT1,SEC24B,FER,MED12L,FGF11,FGF12,FGF13,UBE2E3,IP6K2,SYNCRIP,AGAP3,FOXO3,NBEA,TPK1,CAMKK2,ST6GALNAC3,STAU2,FYB1,ZMAT1,MEGF10,CHL1,GABRG1,GABRG2,TMEM8B,C15orf41,DISC1,CPLX2,MMADHC,USP19,GHR,TTBK1,SPIN1,TOX3,LUZP2,KCNMB4,FERMT2,ADGRA3,PRUNE2,GPR12,STON1,STMN2,CACFD1,RASSF8,TOX2,HMGCL,AGFG1,DHX35,NKD1,ZNF678,ITPKB,KTN1,PAXBP1,NCOA7,MARK1,LRP1B,MEIS2,COL28A1,N6AMT1,MXI1,MYCN,NCAM2,NEK1,NFYA,CNOT4,NOVA1,NUCB2,CHAMP1,OXTR,ABCB1,NALCN,PIK3C2A,FAM218A,ZFYVE21,GPSM2,PURG,MAPKAP1,LRP12,SCHIP1,ING3,SH3KBP1,KANSL1,RANBP3L,PRKAB2,PRKCB,GDPD1,RELN,BCAS3,WBP1L,QRICH1,WDR25,CNTLN,PTCH1,TMEM260,PEX2,PPP2R3C,TMEM255A,FAM66C,SH3TC2,RAP1GDS1,KHDRBS2,TRIM68,ERI2,GTDC1,UBR7,RGS4,RIC8B,RNASEL,GSTCD,NEK11,ATP8B4,RPS6KA2,PTGR2,SATB1,CSRNP3,SCP2,CPEB3,SHMT2,AMBRA1,FBXO11,SEC31A,NUBPL,SLA,PREX2,SLC8A1,BTBD7,LGI3,CABCOCO1,TMCC1,USP33,DOP1A,BDP1,SOX11,DOK5,SPART,ATP10B,THSD1,NKAIN2,CEP68,RGL1,KLHL7,PLCB1,SYN2,EXOC7,TBCEL,ZFP90,SLC19A3,NSD1,GPRIN3,SIK3,ZFPM2,SLC44A1,TIAM1,TK2,BEX4,TPM1,C9orf85,SYNPO2,TSN,PLEKHH2,VLDLR,TBC1D15,P2RY12,XRCC4,PCDH20,ZIC2,TRIM9,ZBTB38,SPIRE1,UPF3A,DHX33,CADM2,PRTFDC1,FIP1L1,FAM47E,PARP11,FZD3,UBE3B,SMIM8,ACTR3B,RSPRY1,NETO2,NETO1,RNF146,SOCS4" MicroRNA hsa-miR-616:mirSVR_lowEffct hsa-miR-616:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-105 1.01E-101 4.03E-104 3.71E-103 289 1759 "CLK4,SYS1,KDM5D,KLHL32,TMEM132B,CCDC85A,GALNT13,BRAP,PTCHD1,BEND6,AP2A2,HECW2,HACE1,NME5,TAOK1,SPARCL1,SEMA6A,SPOP,ALCAM,CEP126,PCDH10,FAM135A,GPRASP2,LRCH2,MAP4K3,LGR5,CDK10,PDE8B,RASL11B,N4BP2L1,RGS11,GPR146,FUBP1,SCAPER,SGCE,CACNA1G,GPC2,RAB29,WASF1,IL33,CA12,CACNB4,PTBP2,CAMK2G,RGN,CBFA2T2,CD38,CDH2,L3MBTL4,DLGAP1,TIGD7,NOG,CHN2,PPT2,DGCR9,CLTC,ABCG2,HECTD1,MAP4K4,AKAP6,COL4A5,COL9A1,RCHY1,COX4I1,NECTIN3,CREM,RBM39,GDA,TRIM69,CSF1R,OSBPL3,VCAN,PHACTR3,PLXNA4,SLITRK5,DZIP3,PLCXD3,PUM1,KIAA0408,BOC,EARS2,KCTD8,PABPC5,GIT2,DNAL1,ARMCX4,ELMSAN1,JAKMIP2,MFAP3L,LYPD1,DDX46,EXOG,GRIN3A,DMD,CASP8AP2,ACOT8,PDCD6IP,MAMLD1,SNX29,EDN1,EDNRA,HIPK3,SUGP2,EGFR,MBNL2,KMT5B,TENM1,ELN,TUBD1,CEP85L,DNAJC27,ADGRV1,ARMCX1,RPS6KC1,TBC1D16,FCGR1A,KAT8,ZNF589,FER,OLFM1,POLR1B,FGF12,FGF14,PRKAG2,FHL1,POLK,IP6K2,FOXO3,SEMA4D,PSD2,EFCAB2,TPK1,ATP2C1,MSANTD4,MPP6,GABRB3,GABRG1,GABRG2,RAPGEF6,IQGAP2,DISC1,CPLX2,IGSF5,NEU3,GCK,GPR162,CYP46A1,ADAM28,PCDH17,TTBK1,COPS8,HPGDS,GLI2,GLYR1,MAP7D2,FERMT2,ATP2B1-AS1,GRB10,PRDM5,GRM8,CIT,GUCY1B1,ATOH8,NCKAP1L,HSF2,C2orf72,GAREM2,IL6ST,INPP1,KLHL23,STXBP5,STMN1,LIG4,LIMS1,SMAD9,MAP6,LYPLAL1,LRP1B,MEIS2,PPM1L,AFF1,SAMD5,MSR1,ZNF92,MXI1,MYT1,NDP,SFR1,CNOT4,NOVA1,LOC100128398,PAX6,PCDH8,PCSK1,PCSK5,PDE1C,PDE4D,NALCN,PURG,TRHDE,MAPKAP1,RETREG2,PRKACB,PRKCB,PRPSAP2,RELN,WBP1L,QRICH1,TMEM260,ZSCAN32,PTPN13,RIPOR1,CCDC40,IQSEC3,SUSD4,RBBP6,RET,FIGN,SLC25A36,LGI2,KLHDC8A,CARF,ROBO2,ZC3H14,GLDN,ADAL,MEG3,ABCA11P,ATAT1,KCNIP3,TRAPPC13,SEMA6D,SH3GL3,MYO18A,SHC4,FHOD3,NLGN1,NUBPL,DHX30,CCDC88A,RCOR3,ANKRD36,CMTR2,SNRPN,MYO16,KDM3A,SP2,HECW1,MYCBP2,TEX2,ERBIN,SEPT8,CEP68,SULF2,ARHGEF9,SYT1,ANKRD28,PJA1,MCF2L,DNMBP,ADGRL3,DMXL2,USP22,SYNE1,SIRT1,SLC44A1,ARL10,TP53BP2,C9orf85,PDSS1,PPIL6,TSC1,LINC00689,PLEKHH2,VSNL1,XRCC4,ZNF28,AGMO,LYPD6,SPHK2,CELF4,ANKS1B,INTS3,EMSY,SLC38A1,PRDM8,TMEM178A,PHTF2,NETO1" MicroRNA hsa-miR-636:mirSVR_lowEffct hsa-miR-636:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-105 1.47E-101 5.86E-104 5.39E-103 271 1550 "DGCR6,ADCY6,GALNT13,RNF157,BEND6,SLC24A4,AP2A1,KCTD16,AK2,TAOK1,ALCAM,CEP126,AMPD2,LCORL,PHF12,TNRC6C,SHROOM2,SPTBN4,ARRB1,RGS20,CDK13,DNAH17,INSYN2B,RNF182,MYOM1,BCHE,NRP2,ZNF599,ARHGEF7,KALRN,CAMK2B,SLC25A14,VXN,PRC1,CBS,USP2,MTMR7,P2RX6,CD86,SCARB1,LRBA,DCLK1,L3MBTL4,LOC730101,MAGI1,DLGAP2,TIGD7,CFL2,SRSF11,CHN2,ABCG2,FHL5,CNTFR,CNTN1,IQCK,LETMD1,CNRIP1,SEC31B,C2CD2,CRYM,MROH8,SNCAIP,CSF1,RGS6,ARHGEF10,OSBPL3,PDE4DIP,CNTNAP2,PLXNA4,DZIP3,CCDC144A,HDAC9,ARHGAP32,RIPOR2,KIF26A,IP6K1,DBN1,ELMSAN1,JAKMIP2,ZNF804A,KIAA0319,ZC3H11A,RHOBTB1,SPOCK3,SEC16A,DMD,DMTF1,DTNA,DTNB,MAMLD1,EBF1,EDNRB,FAM13A,PHF20L1,KMT5B,GOLGA7,EIF4G2,COPS4,RGS17,ELN,PAN3,VPS13B,LRRC17,CD320,ZNF461,TMEM132C,FDFT1,GORAB,FER,MED12L,HPCAL4,FOXF2,APOPT1,ZNF605,HHIPL1,NEURL4,HRASLS5,GABRA3,GCNT2,TUBGCP4,MALT1,LYVE1,TOX3,TNRC6A,ZNF638,GNG4,ADGRA3,GPD1,GPR12,ADAMTS13,GRIN2D,SOX21,MAP4K5,HSF2,SHISA6,IRF8,IL6ST,SLC6A17,ITPKB,KCNN2,KCNN3,KIF2A,STXBP5,LIFR,PAXBP1,MARK1,EFHB,LRP1B,MEF2C,MEIS1,MEIS2,SCAMP5,POC1B,MITF,AFDN,MYO7A,RTL5,P2RY13,NFE2L2,NFYA,NNAT,NOVA1,NTRK2,NUCB2,OGG1,CNTN3,PCDH8,GPR85,SERPINI1,NALCN,SLC25A23,MINDY2,PCDHB17P,PPP2R5E,RASGEF1B,EPDR1,HYDIN,PRPSAP2,BCAS3,WDR25,ELOVL2,PID1,ENOX1,KHDRBS2,RDX,ZMAT4,RGS12,RNASEL,CARF,ROBO1,ROBO2,RPS6KA2,SARS,SATB1,ATXN2,ATXN7,SCP2,GALNT10,SUPT20H,SH3GL3,SHC4,FBXO11,FHOD3,WDR37,ABLIM3,BTBD3,CCDC88A,SLC12A2,TET1,COA1,SMARCD3,INTS9,FAM126B,USP33,FNBP1,UHRF1BP1L,MYCBP2,ERC1,PEG10,LMO3,ST5,CEP68,SULF2,SEPT3,STXBP1,NSFL1C,ARHGEF9,VPS13A,DNAJC9,PLCB1,TMEM150C,SYPL1,SYT1,COBL,ANKRD28,DNMBP,ATMIN,TCF12,CLASP1,SYNE1,FAM200B,ZFPM2,AP4E1,GPR161,CDH22,ACTR6,NR2E1,TRIO,STXBP4,UBE2H,UGT8,VLDLR,ZFP37,ZNF711,ZNF17,ZNF23,NDRG4,CELF4,TMEM237,ANKS1B,CADM2,PRDM8,PRDM10,RNF103,TMEM178A,URM1,UBE3B,TMEM63C,JMJD1C,NLRP3,LAS1L" MicroRNA hsa-miR-188-3p:mirSVR_lowEffct hsa-miR-188-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.29E-105 1.84E-101 7.31E-104 6.73E-103 300 1897 "CLK4,ACTN1,NDRG2,BRAP,RNF150,SLC24A4,C1QTNF3,ARHGAP20,PCDH10,MYH7B,PPFIA4,APBB2,CPNE5,LGR5,SHROOM2,SEMA4G,CASK,SPTBN4,ARRB1,ARRB2,CHRD,CCAR2,ALDH7A1,ADAM15,AZGP1,BBS2,NRP2,PROM1,ARHGEF7,FUBP1,BTK,CA8,DDR1,CACNB4,KALRN,ISPD,RUNX1T1,CBLN1,ZNF501,CLDN10,LDB2,ZMYM4,CCPG1,NDST3,RAB33A,NRXN3,DGCR9,CLTC,SRP14-AS1,HECTD1,LY86,AKAP7,IQCK,LETMD1,SMARCAL1,SEC31B,CREM,RGS6,CSF2RA,IPCEF1,SLITRK5,KIAA0040,ERC2,DCAF4,CYBB,DOCK4,ARHGAP32,GAPVD1,SNPH,RASSF2,MAML1,IST1,B3GAT3,C2CD2L,GSDME,PLPPR4,SNAP91,WDR20,DLX1,GRIN3A,DMD,DMPK,DOCK2,DPH1,DRP2,DTNA,ABCC5,DNM1L,AASDH,EBF1,WDPCP,EDN1,EDN3,PHC2,HIPK3,APH1A,EGFR,MBNL2,KMT5B,EIF4G2,EIF5,C8orf37,DCTN4,ENO2,VPS13B,EPB41,RABEPK,ZNF549,SIRPB1,SCML2,FCGR1A,FCGR3A,FCGRT,SPSB4,FGFR1,BAIAP2,FOXF2,IP6K2,VTI1B,AGAP3,RGPD5,SEMA4D,WDR83,SPECC1,CELF1,NSG1,STAU2,GABBR1,HRASLS5,GALNT15,RAPGEF6,C15orf41,TUBGCP4,SESN1,GHR,TXNL4A,HPGDS,GLYR1,CBX1,KDM2B,GPD1,STON1,GPER1,ADAMTS13,SERP2,GRIN2C,RNF165,RABL2A,MUM1,RASSF8,TOX2,PADI2,SMAP1,IGF1,ZNF678,INPP5B,LINC00634,SYTL4,ASPRV1,SMAD9,MAN2A2,MAP2,MARK1,MBD1,MBP,MEIS1,PPM1L,HS6ST3,NDP,NF1,DNHD1,SMIM11A,SETD4,OPA1,PCSK5,PDE4A,PFKFB2,ZDHHC8,NLGN3,ZFYVE21,GPSM2,PLCB2,TRHDE,EXOSC10,RETREG2,PPARA,PPP1R1A,PPP2R5E,KANSL1,PRKAB2,MAPK4,PSD,CNTLN,PTCH1,NKAIN1,TUG1,PID1,FAM66C,SH3TC2,RDX,RFX2,RFX3,MRPS18A,RIC8B,TMLHE,C12orf49,ALG9,ROBO2,SNX22,FBXW7,SPIN3,CLIP1,RYR3,DGLUCY,ATXN2,ATXN7,SCN2B,SCN7A,PRCD,TNFRSF19,CASC3,GALNT10,COPZ1,SGK1,KIF21A,PPM1E,MYO18A,CNKSR2,NLGN1,ANKRD6,NUBPL,ABLIM3,KANSL3,RADIL,SLC12A2,SLC12A4,BTBD7,TET1,ZNF667,MBD5,SNRPN,TSNAXIP1,ZSWIM8,GLT8D1,TSPYL2,RBM26,SPART,POGZ,RGL1,JMJD6,ZC3H4,ANKRD28,ASTN2,ANKRD12,MTCL1,MLST8,EXOC7,TRIM2,TCF12,NAT16,DOCK9,HIF3A,CYB561A3,ZNF106,CDH22,THRA,TK2,PIK3R5,SYNPO2,DCBLD1,KCNE5,RPRM,UBE2H,UCHL1,FLRT2,ZNF709,PLPPR2,VLDLR,CLDND1,XPO1,ZIC2,ZNF24,ZNF154,EML6,SPIRE1,GDPD5,ADAMTS9,HPS4,KCNAB1,FAM47E,PCBP4,EPM2A,MARCH8,HNRNPA3,TMEM63C,FBXO36,MSRB3,TTC7A,SOCS4,LAS1L" MicroRNA hsa-miR-4276:mirSVR_lowEffct hsa-miR-4276:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.54E-105 2.54E-101 1.00E-103 9.24E-103 299 1887 "RALGAPA1,ASPHD1,ABHD6,KDM5D,TMCC3,RNF150,BEND6,AK2,TAOK1,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,CDK13,ATP2A2,RNF182,DPY19L3,RIPK1,TTLL9,BACH1,ADGRB3,MPDZ,PROM1,THSD7A,CH25H,NFS1,CBR1,METTL6,USP6,MTMR7,C1orf52,ZBED1,CDH2,LOC730101,CLGN,RAB33A,QKI,SULT4A1,ARMC8,AKAP6,ZFP28,FAM171B,CREM,HAPLN1,CS,AATK,RGS6,SEC24C,CSNK1E,OSBPL3,PDE4DIP,PHACTR3,UBXN2A,PHF14,USP6NL,CCDC144A,BOC,TCAF1,DCAF8,TBC1D5,DGKG,HEPH,TMEM130,ZC3H11A,RHOBTB1,SNAP91,SV2B,CHRDL1,RAB39B,HS3ST2,DOCK2,DMTF1,RCAN1,TOM1,ABCC5,KRBA2,E2F6,EDNRB,CNNM1,SUGP2,EIF4G2,TMEM35A,C8orf37,DCTN4,ENO2,SRRM1,ETV1,ANKMY1,EXTL2,NRN1,CLVS1,SH3YL1,CORO2B,DLC1,ZNF589,FER,MED12L,SUCO,SYNCRIP,FLT1,NELFCD,C2orf88,SMC2,ATP2C1,ZNF605,STAU2,MEGF10,GABRB3,RAPGEF6,IP6K3,IQGAP2,SIGLEC8,ZNF559,GCK,ARFIP1,AHDC1,PPARGC1A,MALT1,LYVE1,TTBK1,CRCP,TCERG1,MSL3,LNX1,LILRB4,GPD1,CNTRL,ATP2B1-AS1,DIDO1,FAM19A2,AP4S1,MUM1,FRMD3,MIER3,HLF,HMGCR,AGFG1,LRRC75A,FAM69A,ITGA7,ITGAM,KIF5A,KTN1,LMO2,HECTD2,GPR155,MAN2A2,LYPLAL1,CHIC1,MEF2C,MEIS1,AFF1,MMP16,MPP2,MSI1,ADAM22,MYO9A,ZC3H12B,ALDH1L2,NOVA1,NPTX2,NTRK2,IGSF11,OCRL,CLDN11,P2RX7,GPR137C,GLIPR1L2,PDCD2,PRTG,ENPP2,TMOD2,PFKFB2,PFKFB4,XRN1,PKM,NLE1,JAKMIP1,MTRF1L,PRIMPOL,PMP22,MAPKAP1,STRN3,SCHIP1,EPB41L4B,CEP41,MAPK4,BCAS3,WBP1L,STK32A,ZSCAN32,PTPRB,CASTOR1,PTPRH,NKAIN1,TUG1,SLC25A48,NWD1,REV3L,GTDC1,MRPS18A,SLC25A36,RNASEL,TMLHE,C12orf49,ROBO2,NEK11,FBXW7,KIAA0895L,TCP11L1,ZNF331,TRAPPC13,FAM192A,ATXN2,LRFN5,SCN8A,SCP2,SUPT20H,SH3GL3,FRMPD1,KIF16B,SHC4,FNDC3A,SYBU,ABLIM3,SLA,PREX2,BTBD3,NAPB,ZKSCAN3,CXXC4,SMARCD3,IFT122,SNCA,SNRPN,TMCC1,MYO16,SP4,SPP1,ZBTB43,SPART,POGZ,LARP4,KANK1,VPS13A,TMEM150C,ARC,MTCL1,TBL1X,ATMIN,SATB2,ZEB1,TPCN2,TRIM2,TCF12,DOCK9,PCDHB3,GPRIN3,TEK,PMS2CL,DICER1-AS1,THRA,TIAM1,TMEM9,CDK20,ZNF346,TRO,RUSC1,SSBP2,SGK3,UBTF,UGT8,FLRT2,WRN,GUSBP1,CFAP298,ZBTB14,ZNF23,MKRN3,ZNF138,CELF4,TMEM237,EML6,PCBP1-AS1,ZFAND5,SMARCAD1,SLC38A1,STOX2,GAL3ST3,KCNAB1,UBE3B,PHTF2,FBXO36,ADAMTSL3,RNF170,FRMD6,IFT88,NETO2,DPF3,SOCS4,SENP7" MicroRNA hsa-miR-27b-3p:TargetScan hsa-miR-27b-3p TargetScan 4.91E-105 2.75E-101 1.08E-103 9.91E-103 222 1028 "ASIC1,ABHD6,ELFN2,ADCY6,ADD1,PLEKHH1,PTCHD1,MTA3,HECW2,KCTD16,AK2,PCDH10,PITPNM2,ANK2,APAF1,APBA2,APC,ARNTL,PDE8B,NCOA1,RNF182,DPY19L3,DOCK11,BCL7A,NRP2,KSR1,FUBP1,JAZF1,LDLRAD4,CA12,CACNA1A,CAMK2A,RUNX1T1,CCNT1,C1orf52,LRBA,CDC25B,LONRF2,FOXN3,PLAA,CLCN3,QKI,IGLON5,CNN3,ARMC8,CABP1,LETMD1,COL11A2,SEC31B,CDC42BPB,C2CD2,HAPLN1,CSF1,RIMS4,CNTNAP2,ERC2,CTH,LONRF1,LIN54,DGKG,ELMO1,RAB39B,NR1D2,CDON,ARRDC4,DTNA,E2F6,EDNRA,HIPK3,FEM1B,FAM13A,EBI3,MBNL2,EGR3,EIF5,RGS17,PAN3,EPB41,RCAN2,MTSS1L,NCALD,CEP85L,DNAJC27,EYA1,MED12L,FGF1,FGF14,AMOTL2,PCYOX1,RGPD5,FOXO3,ANKFY1,CELF1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,GABRB3,GCNT2,MSTN,CSDC2,GPR75,KCNMB4,GPD2,ADAP1,DIDO1,GRIN2D,PTPRT,FAM222A,HAS2,MIER3,HMGCR,HNF4G,AGFG1,MSL1,IGF1,IL6ST,INPP1,FAM69A,METTL21A,KCNN3,KPNA5,LIFR,NCOA7,LSAMP,MAN2A2,MAPT,MARK1,AQP11,MATN3,CHIC1,MEF2C,MEIS2,KITLG,MITF,MMP16,MN1,MSI1,LAYN,MYT1,NCAM2,NF1,NFE2L2,ALDH1L2,NOVA1,NRCAM,OPA1,PAX6,PCDH9,CDK18,PDE3A,PDPK1,PKIA,PRKCB,MAPK10,GRAMD1C,RELN,CNNM2,NKAIN1,MARCH1,FAM184A,RASGRF1,RET,FIGN,RFX3,C12orf49,ALG9,ROBO1,FBXW7,HUNK,RXRA,FAM192A,CASC3,FAM102A,PPM1E,ARX,CPEB3,FNDC3A,CCDC92,FAM81A,PKNOX2,CPEB4,EPC1,RCOR3,MBD5,FAM126B,KDM4B,KDM3A,MYCBP2,PEG10,NFASC,ATP10B,CLSTN2,LARP4,NXT2,PRRC2C,ANKRD12,PDLIM2,KLHL4,SATB2,RPGRIP1L,NSD1,CRTC1,GPRIN3,FRYL,NACC2,CBX5,NR2C2,GORASP1,FLRT2,PLEKHH2,BCL2L13,MICU3,MAP3K12,FZD3,ADAMTSL3,JMJD1C,ADAMTS10,FRMD6,NETO1,RNF146" MicroRNA hsa-miR-27a-3p:TargetScan hsa-miR-27a-3p TargetScan 4.91E-105 2.75E-101 1.08E-103 9.91E-103 222 1028 "ASIC1,ABHD6,ELFN2,ADCY6,ADD1,PLEKHH1,PTCHD1,MTA3,HECW2,KCTD16,AK2,PCDH10,PITPNM2,ANK2,APAF1,APBA2,APC,ARNTL,PDE8B,NCOA1,RNF182,DPY19L3,DOCK11,BCL7A,NRP2,KSR1,FUBP1,JAZF1,LDLRAD4,CA12,CACNA1A,CAMK2A,RUNX1T1,CCNT1,C1orf52,LRBA,CDC25B,LONRF2,FOXN3,PLAA,CLCN3,QKI,IGLON5,CNN3,ARMC8,CABP1,LETMD1,COL11A2,SEC31B,CDC42BPB,C2CD2,HAPLN1,CSF1,RIMS4,CNTNAP2,ERC2,CTH,LONRF1,LIN54,DGKG,ELMO1,RAB39B,NR1D2,CDON,ARRDC4,DTNA,E2F6,EDNRA,HIPK3,FEM1B,FAM13A,EBI3,MBNL2,EGR3,EIF5,RGS17,PAN3,EPB41,RCAN2,MTSS1L,NCALD,CEP85L,DNAJC27,EYA1,MED12L,FGF1,FGF14,AMOTL2,PCYOX1,RGPD5,FOXO3,ANKFY1,CELF1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,GABRB3,GCNT2,MSTN,CSDC2,GPR75,KCNMB4,GPD2,ADAP1,DIDO1,GRIN2D,PTPRT,FAM222A,HAS2,MIER3,HMGCR,HNF4G,AGFG1,MSL1,IGF1,IL6ST,INPP1,FAM69A,METTL21A,KCNN3,KPNA5,LIFR,NCOA7,LSAMP,MAN2A2,MAPT,MARK1,AQP11,MATN3,CHIC1,MEF2C,MEIS2,KITLG,MITF,MMP16,MN1,MSI1,LAYN,MYT1,NCAM2,NF1,NFE2L2,ALDH1L2,NOVA1,NRCAM,OPA1,PAX6,PCDH9,CDK18,PDE3A,PDPK1,PKIA,PRKCB,MAPK10,GRAMD1C,RELN,CNNM2,NKAIN1,MARCH1,FAM184A,RASGRF1,RET,FIGN,RFX3,C12orf49,ALG9,ROBO1,FBXW7,HUNK,RXRA,FAM192A,CASC3,FAM102A,PPM1E,ARX,CPEB3,FNDC3A,CCDC92,FAM81A,PKNOX2,CPEB4,EPC1,RCOR3,MBD5,FAM126B,KDM4B,KDM3A,MYCBP2,PEG10,NFASC,ATP10B,CLSTN2,LARP4,NXT2,PRRC2C,ANKRD12,PDLIM2,KLHL4,SATB2,RPGRIP1L,NSD1,CRTC1,GPRIN3,FRYL,NACC2,CBX5,NR2C2,GORASP1,FLRT2,PLEKHH2,BCL2L13,MICU3,MAP3K12,FZD3,ADAMTSL3,JMJD1C,ADAMTS10,FRMD6,NETO1,RNF146" MicroRNA hsa-miR-1243:mirSVR_lowEffct hsa-miR-1243:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-105 2.80E-101 1.09E-103 1.01E-102 276 1612 "CLK4,KLHL32,GALNT13,AP2A2,KCTD16,OSBPL1A,KIAA1324,SEMA6A,SPOP,PCDH10,FAM135A,ZFAT,OGT,DPP10,PARG,APBB2,EPB41L5,LGR5,IGDCC4,CDK13,SLC4A4,ZNF583,ADGRB3,CFLAR,SYNJ2,ARHGEF7,CACNA1G,C5,CALB1,KALRN,VXN,RUNX1T1,PRC1,LDB2,METTL6,CD38,FOXN3,B4GALT6,NDST3,C7orf61,RAB33A,PLAA,MYL6B,MAP4K4,ARMC8,SLC4A8,ZFP28,CNRIP1,CPS1,CLOCK,AKAP12,ANKRD44,OSBPL3,KIAA0040,APPL1,GREB1,KIAA0408,RIPOR2,ZFYVE16,LONRF1,IST1,DGKB,SCRN1,GIT2,ARMCX2,ZNF804A,ZBTB24,ELMO1,ZNF582-AS1,GRIN3A,RAB39B,HS3ST2,USP3,NR1D2,CPEB2,SLC12A6,ECM2,DNM1L,EBF1,WDPCP,EDN1,CNNM1,SEMA3D,KLHL5,TMTC1,MRO,MBNL2,KMT5B,EGR3,GOLGA7,DENND4A,NCALD,CEP85L,ZNF549,SPEG,ETV1,CLVS1,ZNF461,FKTN,FGFR3,PRKAG2,POLK,SUCO,ATP5PD,SYNCRIP,SEMA4D,FLT1,ANKFY1,NOP56,EFCAB2,ZNF605,KHDRBS3,SARAF,OGA,FYN,MEGF10,GABRG1,GABRG2,RAPGEF6,SIGLEC8,DISC1,ADAM28,LYVE1,MSL3,ZNF638,GNG4,GPT2,ADGRA3,TMEM121B,PCLO,FAM19A2,HLF,VSIG4,ACOT7,AGFG1,HSF2,IRF8,SOWAHA,IL12A,CREG2,LIG4,SYTL4,CHIC1,MEF2C,MIA2,MITF,AFF1,XRRA1,GIT1,N6AMT1,LAYN,NEXMIF,NF1,ALDH1L2,VWA2,NOVA1,SMIM11A,OCRL,GNG2,PFKFB2,PIK3R1,SNX10,PLCB2,MTRF1L,PMP22,SCHIP1,ING3,RETREG2,POU6F1,VSTM2L,HYDIN,PRPSAP2,CYBC1,DEF8,CNTLN,BDNF-AS,SPDL1,PTPRD,PTPRN2,ZNF615,CEP97,TMEM255A,FAM66C,ZNF493,REV3L,GTDC1,FIGN,RIC8B,SETD5,EXD2,ALG9,CARF,KIRREL1,ROBO2,BAALC,RPS20,KCNIP1,RXRA,RYR3,S100B,SEMA6D,SUPT20H,SH3GL3,PPM1E,SHMT2,FNDC3A,FHOD3,DZIP1,FAM81A,ARHGEF40,SLC14A1,CPEB4,ABTB1,MAST1,ANKRD36,KIF13A,FAM126B,DOP1A,SP4,KDM4C,UNC5B,PEG10,PBLD,POGZ,SSPO,ELOVL4,JMJD6,ANKRD28,TACR1,CAMTA1,FAM208A,FBXW11,ATMIN,DOCK9,TNS2,SIRT1,DICER1-AS1,MTMR14,PRRT1,CDK20,AMACR,DCBLD1,FAM155A,GORASP1,FLRT2,BCL2L13,VLDLR,P2RY12,CLDND1,RICTOR,KCNK12,ZBTB14,ZIC2,TCEAL7,REEP1,FSTL5,SMARCAD1,CADM2,DNALI1,EVI5,STOX2,PRDM10,CIAPIN1,FAM47E,MPPE1,PDSS2,FZD3,DOCK8,PHTF2,FBXO36,FAM219B,JMJD1C,IFT88,SOCS4,GAN,JPH3" MicroRNA hsa-miR-194*:mirSVR_lowEffct hsa-miR-194*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.36E-105 3.00E-101 1.17E-103 1.08E-102 306 1975 "VWA5B2,ACADM,SYS1,TMCC3,ADD1,UNC5A,KIAA1324,CC2D2A,SEMA6A,LTBP4,FAM135A,ZNF687,LRFN1,EP400,PI16,CCDC146,KCNAB2,APLP1,MAGEE2,DDO,PPFIA3,CDK10,SEMA4G,CADPS,RASL11B,DPY19L3,KIF1A,ADAM23,RGS11,NRP2,BID,CFLAR,FUBP1,MTMR3,CACNA1G,WASF1,CA4,CA8,CACNA1B,DDR1,CACNA2D1,THSD7A,CERS5,MTMR7,P2RX6,LRRFIP1,CRLF1,ASIC3,NRXN3,PPT2,CNN3,FAM149A,COL11A2,COX4I1,SLC35F1,CRY2,CLIP3,LRRC3B,CSNK1E,OSBPL3,GALNT9,SOCS5,UBXN2A,MYADM,KATNAL2,TBC1D5,LIN54,IP6K1,AIF1L,ELMO1,KIAA0753,ZC3H11A,POM121,PLPPR4,SGSM2,GRIN3A,DYNC1I1,CDON,SLC12A6,DPYSL2,DRP2,TOM1,DUSP9,ABCC5,EGFR,AASS,EIF4G2,EIF5,PLEKHA1,ING4,ELN,VPS13B,EPHB1,SLC43A2,SRRM1,IGSF6,HSPA12B,NRN1,F5,NSRP1,FCGRT,ZSCAN30,OLFM1,SPSB4,FGF14,MAD2L2,FHL1,SUCO,IP6K2,SEMA4D,NOP56,FLYWCH1,NELFCD,AKAP3,NBEA,TPK1,RASL10A,CAMKK2,ST6GALNAC3,TPPP3,AP4B1,GABBR1,GABRA3,RAPGEF6,IQGAP2,C15orf41,SEPT9,TUBA8,ARFIP1,WASHC2A,CYP46A1,CSDC2,DHRS4,TCERG1,GLYR1,LUZP2,LOXL3,GNAO1,WDFY3-AS2,GPR34,GRB10,PLCD4,SERP2,GRM2,ZNF496,GSTM5,FAM107A,TOX2,ATXN2L,AGBL5,IRF8,MSL1,INPP5B,ITPKA,ITPKB,KCND1,KCNN1,KCNN3,GATD1,MAP6,MAT2A,MBNL1,MEST,SAMD5,MXI1,MYO7A,MYO9A,RTL5,ALDH1L2,NINJ2,NPTX2,PCBP3,OPA1,P2RY1,PCSK1,PDE1C,PDE1B,ENPP2,GPR85,ZNF655,PKD1,TMEM38A,KCTD15,PLCL1,SLC25A23,PDZRN4,SDK2,IRX1,PRKCB,EPDR1,GRAMD1C,DIRAS2,KLK6,PIGG,BDNF-AS,PTK2,PTPRB,PEX2,ZSCAN2,ACSS3,RDX,TRIM68,RET,RFX3,PRIMA1,RNASEL,RNH1,ARMC5,KIRREL1,ROBO2,ELP2,NEK11,FBXW7,BAALC,ZNF671,GLDN,TCP11L1,ATAT1,KCNIP1,ZNF331,TRAPPC13,FNIP1,PEAR1,ZNF821,GALNT10,FAM102A,SH3GL3,FERMT1,FNDC3A,ANKRD6,WDR37,PREX2,BTBD3,EPN2,SLC6A8,KDM4D,SIRT2,SLC12A2,ELMO2,ATF7IP,TET1,CXXC4,MBD5,FAIM2,FAM126B,BDP1,NMNAT2,MYCBP2,CDK19,NFASC,LHPP,NKAIN2,ERBIN,DIP2A,STAC2,ADHFE1,ARHGEF9,VPS13A,SYN2,SLC37A2,TACR1,MTCL1,IQCE,KLHL4,TCEA1,SATB2,ZFP90,PCDHB4,NSD1,HIF3A,CYB561A3,DICER1,RIMBP2,RASD2,WBP2,ZNF346,TRO,ZKSCAN5,RPRM,CLEC2L,UGT8,OSBP2,VLDLR,NPDC1,LGI4,CFAP298,SLC47A2,ZNF19,ELFN1,LYPD6,TCEAL7,ZSCAN26,UPF3A,EMSY,GDPD5,CIAPIN1,SIGLEC10,URM1,ITM2C,DNAH10,MRPL47,UBE3B,SMIM8,RNF170,NETO1,LAS1L" MicroRNA hsa-miR-4255:mirSVR_lowEffct hsa-miR-4255:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.83E-105 3.26E-101 1.27E-103 1.16E-102 276 1613 "RALGAPA1,ASPHD1,KLHL32,ADD2,ADORA1,OLMALINC,AP2A2,OSBPL1A,ALCAM,UNC79,FAM135A,AMPD2,CDC42BPA,DPP10,ANK2,VAT1L,TNRC6C,LGR5,CASK,CDK13,ZSCAN18,CCAR2,ATP2A2,N4BP2L1,RIPK1,BCHE,IL33,DDR1,CACNB4,CALB1,KALRN,PTBP2,CAMK2A,CAMK2B,CAST,CBLN1,CBR1,CBFA2T2,LRBA,CDH2,DCLK1,MAGI1,CDO1,TIGD7,NDST3,QKI,IGLON5,CNN3,MYRIP,CPS1,SEC31B,ANKRD44,CSF1,LRRC3B,CSNK1G3,FAM169A,SLITRK5,PPP1R16B,CTH,PUM1,RUBCN,BOC,DOCK4,ZFYVE16,LONRF1,LIN54,IP6K1,BRINP1,GIT2,JAKMIP2,KLHL3,SNAP91,DMD,DYNC1I1,CDON,DMTF1,SLC25A18,PDCD6IP,DTNA,DTNB,ECM2,ABCC5,DNM1L,E2F5,EDN3,EDNRA,CNNM1,KLHL5,TMTC1,YAF2,FAM13A,EGFR,RASA4,KCTD3,STARD3NL,SRRM1,DENND4A,CLVS1,ABCA8,ACSL4,DLC1,CHST15,FCGRT,SEC24B,FER,FGF11,PRKAG2,POLK,FOXF2,SYNCRIP,FOXO3,C2orf88,ATP2C1,STAU2,MEGF10,GABRG2,IQGAP2,ZNF559,C15orf41,LRRC37A6P,IGSF5,TUBA8,MSTN,ARFIP1,MALT1,TTBK1,COPS8,SPIN1,DCLK2,LNX1,PCLO,ATP2B1-AS1,GRIA2,DIDO1,PLCD4,FAM19A2,LINGO1,ADAMTS6,BACH2,MIER3,ELOVL5,NEGR1,MSL1,IFI16,SLC35G1,METTL21A,KIF2A,KTN1,LIFR,ZNF667-AS1,MAN2A2,LYPLAL1,MAT2A,MATN2,MATN3,MEF2C,MEIS2,KITLG,AFDN,MMP16,MYO9A,NCAM2,NEK1,VWA2,NOVA1,SLC11A2,NTRK3,SETD4,P2RY1,GPR137C,TREM2,GLIPR1L2,PDE3A,ENPP2,FAM98B,NLGN3,TMIE,XRN1,NLE1,PLCL1,PLEC,PLXNB1,PRIMPOL,PMP22,PSAT1,ING3,RETREG2,FA2H,MINDY2,PPP2R5E,RASGEF1B,EPDR1,MASP1,APTX,PTCH1,PTK2,ZSCAN32,PTPN13,NKAIN1,TTC13,PPP2R3C,USP47,FAT4,KHDRBS2,RDX,REV3L,RFX3,FBXW7,BAALC,GLDN,HSD11B1L,ATXN2,TRA2B,SGK1,SH3GL3,CHD9,FBXO11,DZIP1,NUBPL,BTBD3,KANSL3,BTBD7,SLC22A4,INTS9,DOP1A,SP4,NMNAT2,KDM4C,TSPYL2,NFASC,POGZ,ITPRID2,SSTR1,SSTR2,SEPT8,CEP68,VPS13A,ARC,SYT1,ANKRD28,MTCL1,TBCEL,KLHL4,TCF4,SATB2,CUX2,ZEB1,SYNE1,PCDHA5,FRYL,SIRT1,ITGB3BP,AP4E1,TIAM1,RIMBP2,PIK3R5,DCBLD1,TSC1,TTC3,ZKSCAN5,ZNF709,BCL2L13,ZNF781,RICTOR,TCEAL7,CADM2,STOX2,ADAMTS9,NAV3,KCNAB1,PLSCR4,PDSS2,AMN1,FZD3,NHSL1,FXR1" MicroRNA hsa-miR-4298:mirSVR_lowEffct hsa-miR-4298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.27E-105 3.51E-101 1.36E-103 1.25E-102 282 1684 "ACADM,EMILIN3,KDM5D,NDRG2,FMNL2,TMEM132B,PTCHD1,ADRA1D,FAHD2CP,C1QTNF3,ALCAM,PCDH10,AMPD2,CDC42BPA,EP400,CCDC146,LCORL,PPFIA4,PHF12,LGR5,CDK10,SEMA4G,IGDCC4,ARHGDIG,ARRB2,SLC4A4,ALDH7A1,ATP6V0A1,KIF1A,ADAM23,MPDZ,SEC11C,BID,CFLAR,SYNJ2,AP1M1,GPC2,CACNB4,CALM1,CAMK2B,CARS,SPAG9,USP6,P2RX6,AP4M1,CDC25B,L3MBTL4,MAGI1,CCPG1,NOG,PLEKHB1,STOML1,MAP4K4,FHL5,IQCK,AKAP6,TBPL1,SMARCAL1,NECTIN3,SLC35F1,CRY2,SNCAIP,CSF2RA,OSBPL3,VAC14-AS1,PDE4DIP,ERC2,UBXN2A,KIAA0408,BOC,DCAF8,IST1,GIT2,ARMCX4,ELMSAN1,RUSC2,C2CD2L,TMEM130,POM121,EXOG,DMD,SLC29A4,CDON,DMTF1,DPH1,PDCD6IP,DUSP9,PHC2,PHF20L1,SUGP2,TNK2,CALCRL,ENO2,EPB41,CEP85L,ZNF549,MRPL37,EZH1,ZNF585B,TBC1D16,TAOK3,DLC1,CHST15,FKTN,KAT8,MED12L,IP6K2,PSD2,C2orf88,EFCAB2,UFM1,FAM49B,ATP2C1,ERGIC3,CELF1,CGREF1,FYN,GABBR1,GABRB3,TRAF3IP2,GCK,ALDH1L1,GCNT2,CYP46A1,PPARGC1A,ZNF276,COPS8,GPT2,ADGRA3,GPER1,ADAMTS13,CACFD1,SLC2A6,ATOH8,IRAK3,ATXN2L,SHISA6,IRF8,MSL1,LRRCC1,DISP2,ITGA7,METTL21A,KCNK3,CREG2,TTYH2,PAXBP1,HECTD2,MAN2A2,MAP4,ADAM11,MEIS1,MEST,KCTD6,SCAMP5,AFF1,MN1,DBNL,PTOV1,ZNF862,NBL1,NNAT,NOVA2,SLC11A2,OGG1,P2RX7,PCSK5,CDK18,PDE4A,ENPP2,FAM98B,GPSM2,NLE1,PLIN1,PURG,PNMA3,EXOSC10,SCHIP1,RETREG2,SEPT4,FA2H,PPP1R1A,PCDHB17P,PPP2R2C,VSTM2L,GRAMD1C,MASP1,ANKHD1,PTPRE,CASTOR1,PEX2,TMEM231,CEP97,CCDC40,IQSEC3,NWD1,RASGRF2,RFX2,PRIMA1,SLC25A36,ARMC5,YY1AP1,RPE,FBXW7,BAALC,KIAA0895L,MCMBP,ADAL,ST6GALNAC6,ZNF354C,DGLUCY,ATXN7,PRCD,SCP2,MYO18A,SHC4,FNDC3A,ABLIM3,SLC2A5,PEX26,LIMS2,NAPB,OGDHL,SMARCD3,RCOR3,CABCOCO1,PDZD2,BDP1,SP2,ZSWIM8,ATP10B,CAMTA2,SSTR1,ZC4H2,LARP4,STAC2,ADHFE1,NSFL1C,COBL,SLC37A2,PDLIM2,KLHL4,WSCD1,SATB2,TPCN2,RPGRIP1L,TCF12,NAT16,PHF24,PUM2,USP32P1,C18orf54,TIMP4,LRRC8A,FAM124A,TNS1,TPM1,WBP2,SMUG1,ELP5,UBE3A,PLPPR2,VLDLR,P2RY12,RICTOR,GUSBP1,NDRG4,LYPD6,TCEAL7,ZNF189,SPIRE1,EMSY,PRTFDC1,DNALI1,GDPD5,STOX2,FIP1L1,ITM2C,FBXO36,JMJD1C,FRMD6,IFT88" MicroRNA hsa-miR-27b:mirSVR_highEffct hsa-miR-27b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.09E-104 6.10E-101 2.35E-103 2.16E-102 269 1536 "RALGAPA1,NCKAP5,CCDC85A,ADORA1,KIAA1211,PTCHD1,OLMALINC,ZNF608,INTS2,HACE1,WDR35,TAOK1,SEMA6A,ALCAM,ANK2,SEMA7A,PKP4,APBA2,DDO,VAT1L,NCOA1,STX16,ZNF582,RNF182,RIPK1,NRP2,BLM,PROM1,C5,CACNA1A,CABP7,MTMR7,SCARB1,C1orf52,ZMYM4,MAGI1,CFL2,SRSF11,MS4A7,CLCN3,QKI,CNN3,ARHGEF6,AKAP7,ARMC8,LETMD1,ZFP28,ZNF385A,SLC35F1,CRMP1,HAPLN1,GDA,SEC24C,LRRC3B,SUSD5,VCAN,HDAC9,RIPOR2,DCAF8,LONRF1,KCTD8,DGKB,TMEM170A,PABPC5,POM121,SNAP91,CHRDL1,GRIN3A,NR1D2,RCAN1,ARRDC4,DTNA,DNM1L,E2F5,EBF1,EDNRA,TMTC1,FAM13A,EGFR,MBNL2,ASB3,EIF5,RGS17,CALCRL,EPB41,RCAN2,EYA1,EZH1,HSPA12B,FGF1,FGF12,FGF13,FGF14,SUCO,RGPD5,ST6GALNAC3,NSG1,AP4B1,BRSK1,OGA,NEURL4,GABRB3,IQGAP2,ERAP1,DISC1,NEU3,ARFIP1,PPARGC1A,GLI2,GLYR1,TOX3,ZNF638,ADGRA3,GPD2,GPR37,RNF165,RNFT2,FAM222A,ZHX1,MIER3,CFAP126,HSPA1L,MSL1,ZNF181,SOWAHA,ZIC5,ZNF678,INPP1,NME9,KCNJ16,CREG2,STXBP5,PAXBP1,HECTD2,NCOA7,SMAD1,SMAD9,MARK1,LYPLAL1,MAT2A,AQP11,MATN3,MBD1,MEIS2,KITLG,ZNF680,MXI1,P2RY13,NEK1,NF1,NFE2L2,CNOT4,NOVA1,PCDH9,PDE3A,PRIMPOL,LRP12,SEPT4,PPM1B,PPP3CA,CEP41,PKIA,PRKCB,MAPK9,GRAMD1C,HYDIN,DCHS2,RELN,DEF8,PIGG,CNTLN,MTMR10,ZSCAN32,QDPR,SH3TC2,FAT4,FAM184A,ENOX1,ZNF493,KHDRBS2,RET,REV3L,ERI2,RFX3,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,TMLHE,RORB,ELP2,FBXW7,ATP8B4,MEG3,NCBP3,TRAPPC13,ARX,CPEB3,SHC4,HKDC1,CHD9,SLA,EPN2,SLC8A1,KBTBD4,ZNF334,TET1,CPEB4,RCOR3,SNAP25,SNRPN,TMCC1,BDP1,KDM3A,KDM4C,PEG10,TROVE2,ZNF302,SSTR1,LARP4,ERBIN,NXT2,SEPT8,TTBK2,NECAB1,ARHGEF9,VPS13A,TACC1,CAMTA1,TAF9,PDLIM2,TCEA1,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,USP32P1,FRYL,SIK3,FAM200B,THRA,ACTR6,CSMD1,TPM1,NPL,SYNPO2,TSC1,TTC3,TUBB2A,CLHC1,GORASP1,PLEKHH2,ZNF709,ZNF781,XPO1,ZNF708,ZNF540,MKRN3,FSTL5,ZSCAN26,SMARCAD1,DHX33,TMEM178A,DOCK8,JMJD1C,ADAMTS10,NETO1" MicroRNA hsa-miR-4314:mirSVR_lowEffct hsa-miR-4314:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-104 6.35E-101 2.43E-103 2.24E-102 297 1869 "EMILIN3,SYS1,XKR4,NDRG3,TMEM132B,ADORA1,ADORA2A,PWWP2A,RNF150,BEND6,CEP126,FAM135A,SYT13,CDC42BPA,PI16,MADD,IGDCC4,PLA2G4C,LINC00173,NUMB,ATP2A2,DPY19L3,DNAJC27-AS1,KSR1,BMPR1B,ST3GAL5,AP1M1,CACNA1G,RAB29,LURAP1,VXN,SPAG9,ENTPD6,KCNAB3,LRRFIP1,L3MBTL4,LARGE1,DLGAP2,NOG,RAB33A,C4orf33,QKI,CNTN1,WHRN,LETMD1,COL11A2,SMARCAL1,CRY2,CRYBB1,GDA,CRYM,SNCAIP,RGS6,ARHGEF10,OSBPL3,SUSD5,PDE4DIP,SLITRK5,KIAA0040,SEC14L5,CYBB,ARHGAP32,TCAF1,ZNF337,DAPK1,SCRN1,GIT2,PITPNC1,ZBTB24,RUSC2,ALKBH8,RHOBTB1,MTX3,WDR20,DMPK,USP3,DOCK2,DMTF1,RCAN1,DTNB,FAM78B,DNAJB6,DNM1L,EBF1,EDNRA,SEMA3D,TMTC1,APH1A,EGFR,MRO,GOLGA7,ASB3,DCTN4,EMX2,EPHB1,ERBB2,PIPOX,DNAJC27,ADGRV1,F8,ZNF461,TUBA1B,ST3GAL6,OLFM1,UBE2E3,HPCAL4,ANKFY1,SLC37A3,FOLR2,COQ5,TRIM16,ZNF605,CELF1,TPPP3,NEURL4,CHL1,TMEM8B,DISC1,SEPT9,INPP5K,ACSS1,ARFIP1,CYP46A1,GGT7,GGT5,TTBK1,COPS8,POLL,PRRC2B,PRUNE2,CCDC184,ADAMTS13,RNF165,ZBTB49,PSIP1,SLC2A6,IRAK3,ATXN2L,SYNPO,AGBL5,ZIC5,DISP2,SCIN,LRRTM1,ITPKA,ITPKB,METTL21A,L1CAM,LMO2,SYTL4,NCOA7,LSS,ZFYVE27,MARK1,MBD1,MBNL1,MBP,ADAM11,MEIS1,MEST,KITLG,PPM1L,AFF1,MPP2,COL28A1,HS6ST3,LYRM9,MYO6,MYO7A,HNRNPM,CNOT4,SLC11A2,PDE1B,GPR85,SERPINI1,XRN1,PLCL1,SLC25A23,PMP22,LRP12,EXOSC10,FA2H,C19orf57,DRAM2,PCDHB17P,PPP2R5E,PRKAB2,PKIA,HYDIN,MASP1,WBP1L,PTCH1,ANKHD1,ELOVL2,TMEM260,C1orf109,ZSCAN2,PPP2R3C,SH3TC2,RASGRF1,RASGRF2,ZMAT4,TRIM68,RET,GTDC1,UBR7,CARF,NEK11,MCMBP,RPS6KA2,ST6GALNAC6,ZNF331,DGLUCY,SEMA6D,PRCD,SEC14L1,GALNT10,MRAS,SUPT20H,SCAF8,FBXO11,FNDC3A,WDR37,PPP4R3A,EPN2,SLC11A1,LIMCH1,MBD5,TMCC1,PDZD2,BDP1,NMNAT2,GLT8D1,ZNF423,SPTAN1,SSTR1,ST5,ZSCAN29,CEP68,STX1A,SEPT3,JMJD6,NUDT10,PLCB1,ARC,TACC1,TAL1,AGTPBP1,TBL1X,KLHL4,SATB2,TPCN2,TCF12,CLASP1,SZT2,DOCK9,USP32P1,HIF3A,RNF175,ZNF106,GALNT17,TLR4,TMPO,FAM124A,BEX4,PIK3R5,TP53BP2,CDK20,SYNPO2,PDSS1,TSC1,LINC00689,UGT8,LAT2,WRN,RICTOR,XRCC4,TRIM9,ZBTB38,TMEM237,ZNF189,ZNF213,UPF3A,INTS3,NT5M,STOX2,GAL3ST3,NAV3,PPP1R3F,TRIM16L,RGS7BP,ST7,PHTF2,CASC15,RNF170,TTC7A,SOCS4" MicroRNA hsa-miR-3132:mirSVR_lowEffct hsa-miR-3132:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-104 6.55E-101 2.50E-103 2.30E-102 249 1313 "ASIC1,CLK4,C3orf14,NDRG2,GALNT16,CCDC85A,ADD1,ADRB2,MTA3,SLC24A4,OSBPL1A,KIAA1324,WDR35,CC2D2A,TAOK1,ALCAM,GPRASP2,CDC42BPA,C6orf89,CCDC146,PHF12,APAF1,UPRT,SHROOM2,AQP6,SFMBT2,PRX,TMEFF1,NUMB,CHID1,ATP1A1,EIF4G3,ATP6V0A1,TTLL9,BBS2,BCHE,MIR9-3HG,ZNF599,BMP7,ARHGEF7,SCAPER,GYG2,CACNA1I,RAB29,CACNA1B,CALB2,PTBP2,PRC1,ARHGEF1,DGKI,LRBA,SEPT7,SOCS6,NDST3,CPNE6,SRP14-AS1,HECTD1,AKAP7,IQCK,AKAP6,AHCTF1,HINFP,ABCG1,CRYM,CS,CSF1,SUSD5,CST3,KIAA0040,UBXN2A,DCAF4,SEC14L5,GAPVD1,DGKG,AIF1L,GIT2,ZBTB24,KLHL3,PLPPR4,SV2B,SGSM2,FAM107B,GRIN3A,RAB39B,SHANK1,E2F5,E2F6,EDNRB,HEYL,RASGRP1,PHF20L1,APH1A,EIF4G2,TENM1,CALCRL,DCTN4,GPHN,ARMCX1,NSRP1,CORO2B,CHST15,FCGRT,KAT8,POLR1B,FGF11,SPSB4,FGF14,PRKAG2,SUCO,HPCAL4,FOXF2,TMEM107,APOPT1,ATP6V1H,CELF1,ZNF44,CHL1,GAD1,ACSS1,GATM,GFER,MMADHC,USP19,DBF4,ZNF638,GPD1,SPACA9,GRM8,CIT,COQ10A,ZBTB45,HAS2,ELOVL5,SYNPO,ZDHHC15,SHISA6,FAM95B1,GAREM2,IL6R,KCNH2,GATD1,TTYH2,MAN2A2,MAT2A,MEIS1,MN1,MPP2,MSR1,NRBP2,SAMD14,MXI1,MYO7A,NFYA,NINJ2,NME4,NOVA1,DNHD1,NTRK2,IGSF11,PCSK5,CDK18,PDE1B,GNG2,ZNF655,GPSM2,FAM216A,PLEC,LRP12,SH3KBP1,RASGEF1B,EPDR1,WBP1L,TMEM104,PIGG,CNTLN,ELOVL2,ZIK1,PTPRD,PTPRO,TUG1,RASGRF1,ZDHHC14,UBR7,SLC25A36,ARMC5,CCDC25,STK32B,CLIP1,DGLUCY,ATXN2,CASC3,GALNT10,CPEB3,MYO18A,AMBRA1,LIMS2,PKNOX2,SLC22A4,MAST1,SNRPN,PDZRN3,DOP1A,UNC5B,IQSEC2,TSPYL2,RBM26,CAMTA2,SSTR1,ZC4H2,RGL1,DNAJC9,SYP,TACR1,EXOC7,RPGRIP1L,ARHGAP9,RNF216P1,AKTIP,ARL10,NPL,WBP2,SMUG1,TRPM2,PPIL6,CA14,PRR18,BCL2L13,PLPPR2,TOM1L2,WIPF1,LAT2,LGI4,TRIM9,MKRN3,SPHK2,ZBTB38,REEP1,SPIRE1,ZFAND5,SMARCAD1,STOX2,GAL3ST3,SLC17A7,WNK3,EPM2A,DOCK8,PHTF2,JMJD1C,ST8SIA2" MicroRNA hsa-miR-329:mirSVR_lowEffct hsa-miR-329:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-104 6.66E-101 2.53E-103 2.33E-102 285 1724 "VWA5B2,KCNH8,CLK4,CCDC85A,ADD1,KIAA1211,CC2D2A,TAOK1,SMIM17,SEMA6A,ALCAM,ABCD2,DPP10,FGD2,PPFIA4,PKP4,APBA2,FAM131A,PHYHD1,SHROOM2,NCOA1,NUMB,INSYN2B,ATP2B2,SLC2A11,MYOM1,ADAM15,BACH1,BBS2,NRP2,CFLAR,BMP7,FUBP1,NAE1,BTK,GYG2,BAIAP3,CFAP410,CACNA2D1,KALRN,CAMK2B,CLDN10,LDB2,METTL6,USP6,LRBA,L3MBTL4,NOG,NUMBL,CACNA2D2,HECTD1,AKAP7,AHCTF1,RTTN,CREM,CRY2,HINFP,ANKRD44,CSNK1E,SUSD5,PLXNA4,SLITRK5,DZIP3,ERC2,RASSF2,MATR3,SPOCK2,YTHDC1,ZBTB24,PLPPR4,SNAP91,SACS,WDR20,CHRDL1,EXOG,GRIN3A,DMD,DMPK,CASP8AP2,PDCD6IP,DTNA,ABCC5,CNNM1,SEMA3D,APH1A,KMT5B,EGR3,C3orf18,EPB41L2,GPHN,ERBB2,DENND4A,NSRP1,DLC1,OLFM1,PCYOX1,SYNCRIP,AGAP3,RGPD5,FOXO3,COQ5,SMC2,FAM49B,ZNF605,ERGIC3,CELF1,CGREF1,NSG1,STAU2,ABLIM2,TVP23A,CHL1,GALC,TMEM8B,ACSS1,CPLX2,SESN1,GGT5,BRD8,TXNL4A,TCERG1,CBX1,ZNF782,GPT2,ADGRA3,PRUNE2,CCDC184,MCHR1,GPR34,GRIA2,DIDO1,RNF165,GSTM5,AP4S1,MIER3,IRF8,MSL1,RBPJ,ITPKB,KCNH2,KIF2A,KIF5A,STXBP5,LAMP2,LMO2,SYTL4,NCOA7,MAP2,MARK3,MAT2A,CHIC1,MEIS1,MGAT3,LYRM9,MYO7A,MYT1,P2RY13,NEK1,NOVA2,SMIM11A,NUCB2,TBC1D25,P2RX7,GPR137C,PALM,CNTN3,PDCD2,PDE3A,NALCN,PIK3R1,PRIMPOL,LRP12,EPB41L4B,PPM1B,RASGEF1B,MAPK4,PRPSAP2,BCAS3,VPS13C,PTCH1,PTPRD,PTPRO,RAD17,SH3TC2,ZNF493,RADX,KHDRBS2,ZDHHC14,REV3L,RFX3,PRIMA1,RIC8B,RNH1,EPHA10,SGSM1,ST6GALNAC6,ZNF331,DGLUCY,FNIP1,CASC3,MRAS,TRA2B,FAM102A,SEC31A,DZIP1,KANSL3,SLC6A11,SLC12A4,NAPB,ELMO2,SLC22A4,CDK5RAP2,MYH15,RCOR3,IFT122,INAVA,FAM219A,TRERF1,BDP1,ZSWIM8,SPP1,KDM4C,ZC3H13,POGZ,ITPRID2,ZC4H2,MPRIP,SEPT8,TTBK2,SULF2,ZC3H4,SYNE2,SYPL1,SYT1,COBL,C12orf76,CAMTA1,MLST8,TAL1,ADGRL3,AGTPBP1,TBL1X,SIN3B,DMXL2,ZFP90,TPCN2,USP22,SYNE1,NAT16,PCDHB9,TNS2,HIF3A,CYB561A3,ITGB3BP,SLC44A1,TMEM9,TLR4,BEX4,TP53BP1,ZNF346,PDSS1,NEIL2,TRPS1,SSBP2,EIF4ENIF1,LMF1,XPO1,ZNF711,ZNF24,TRIM9,LYPD6,TCEAL7,TMEM237,FSTL5,SMARCAD1,LINC02210,RNF103,HPS4,KCNAB1,MSRB3,TTC7A,FRMD6,IFT88,NETO2,ST8SIA2" MicroRNA hsa-miR-520h:mirSVR_highEffct hsa-miR-520h:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-104 6.70E-101 2.54E-103 2.34E-102 250 1324 "RALGAPA1,SYN3,KLHL32,ESYT2,BEND6,SLC24A4,ZNF608,INTS2,RTL9,KIAA1324,WDR35,ALCAM,GPRASP2,PARG,APC,CDK13,STK33,EIF4G3,ATP2A2,ADGRB2,ADGRB3,MPDZ,FUBP1,JAZF1,SGCE,CALB2,SLC25A14,CAST,HIP1R,CERS5,CBFA2T2,MAGI1,CCPG1,CLGN,B4GALT6,LHX2,RAB28,ABCG2,CNR1,AKAP7,ARMC8,FAM149A,AHCTF1,CDC42BPB,CREM,ENTPD4,ANKRD44,GDA,LRRC3B,CSNK1E,OSBPL3,RUBCN,GPRASP1,RIPOR2,DBN1,HEPH,TIAM2,DDX46,RHOBTB1,SNAP91,RAB39B,USP3,DMTF1,DNAJB6,DNM1L,EDNRA,FCF1,RASGRP1,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,IRAK4,COPS4,PLEKHA1,C8orf37,DCTN4,TUBD1,EPB41L2,EYA1,CLVS1,ACSL4,SCML2,CEP78,FDFT1,GTF2IRD2,FGF12,FOXF2,RGPD5,IQCG,ANKFY1,C2orf88,EFCAB2,JKAMP,TRMO,NBEA,ATP6V1H,KHDRBS3,MSANTD4,MPP6,OGA,HRASLS5,INPP5K,TCERG1,COPS8,TOX3,TNRC6A,ZNF638,DCLK2,FUT10,DIDO1,GRIN2C,ZNF496,CIT,GSTT2,LINGO1,HAS2,MAN1B1,MSL1,ZNF678,METTL21A,KCNN2,IPO5,TTYH2,LIMS1,HECTD2,ZFYVE27,MAP6,MAT2A,MBNL1,MEIS1,SRSF12,MEST,MID1,MXI1,MYCN,RTL5,NCAM2,SLC11A2,SETD4,OCRL,OGG1,LOC100128398,GPR137C,CNTN3,PCDH8,PRTG,PDE4A,PDE4D,FAM216A,PPP3CA,KANSL1,PKIA,HYDIN,WBP1L,CNTLN,PTK2,PTN,TMEM260,PTPN13,PTPRO,ZNF793,MSANTD2,RFX3,RGS3,RNASEL,CARF,ROBO1,ELP2,FBXW7,ATAT1,KCNIP1,RYR3,DGLUCY,SALL1,ATXN7,LRFN5,SCP2,TNFRSF19,HSPA4L,SH3GL3,FERMT1,CPEB3,CHD9,FBXO11,FHOD3,NLGN1,SLA,BTBD3,DHX30,SEPHS1,ARHGEF40,GKAP1,DMRTC1,CDK5RAP2,ZNF415,FAM126B,SPP1,ERC1,ZBTB43,ITPRID2,MESP1,SAMSN1,ZC4H2,SS18,ELOVL4,SEPT8,ARHGEF9,PLCB1,SYT1,FBXW11,TCF4,SATB2,TCF12,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,AP4E1,THRA,HEY1,TMPO,RIMBP2,TPM1,PDSS1,AMACR,ZKSCAN5,GORASP1,PLEKHH2,VLDLR,TBC1D15,LAT2,CLDND1,SLC47A2,ZNF74,FIP1L1,FAM47E,RTN4,PHTF2,ADAMTSL3,JMJD1C,FRMD6,DPF3" MicroRNA hsa-miR-548c-3p:PITA hsa-miR-548c-3p:PITA_TOP PITA 1.27E-104 7.09E-101 2.68E-103 2.46E-102 238 1196 "CLK4,TMEM132B,USP31,PWWP2A,PCDH19,HACE1,TAOK1,SPOP,FAM135A,PDZD4,PITPNM2,OGT,PKP4,USP37,CDC14B,TMEFF1,ZBTB10,CHRD,NCOA1,ATP1A1,SLC4A4,ATP2B2,JAZF1,LDLRAD4,THSD7A,CALM1,PTBP2,RUNX1T1,LDB2,NUMBL,SOCS6,CLTC,QKI,CNTN1,ARMC8,AKAP6,AHCTF1,IGDCC3,CLOCK,CRMP1,ERC2,APPL1,PLCXD3,CTH,USP6NL,KIAA0408,HDAC4,MATR3,DGKB,DBT,DDX46,POM121,SGSM2,MTX3,DLX1,CPEB2,CASP8AP2,E2F5,EBF1,SNX29,HIPK3,APH1A,MBNL2,KMT5B,EGR3,TMEM132E,TENM1,PLEKHA1,CALCRL,PAN3,DCTN4,EMX2,EPB41,EPB41L2,RCAN2,SRRM1,ERBB4,EYA1,ARMCX1,TAOK3,DLC1,FGF11,AFF2,FAM49B,ST6GALNAC3,STAU2,FUT9,SARAF,OGA,MEGF11,CHL1,IQGAP2,C15orf41,GHR,PPARGC1A,TCERG1,TNRC6A,ZNF638,GPD2,TDRKH,STON1,GRIA2,PRDM5,FAM19A2,LINGO1,MAP4K5,FRMD5,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,LRRTM1,KCND2,MAP2,MAT2A,MATN2,MBNL1,MEIS1,AFDN,MYCN,NEXMIF,NEK1,NFIX,PCSK1,PRTG,PDE4D,PFKFB2,OLA1,NLGN3,PIK3C2A,PIK3R1,SMOX,LRP12,SH3KBP1,KANSL1,PRKAB2,ELOVL2,PTN,PTPRD,TMEM255A,RBBP6,RBBP8,KHDRBS2,ZMAT4,RET,REV3L,FIGN,RFX3,PBRM1,ZFHX4,CCDC82,SETD5,ALG9,CARF,ROBO1,PCMTD2,RPE,SPIN3,RPS6KA2,CLIP1,RXRA,NCBP3,SATB1,ATXN7,FNIP1,TNFRSF19,SEC14L1,MRAS,TRA2B,CPEB3,SHC4,CHD9,FBXO11,NLGN1,PPP4R3A,WDR47,PKNOX2,SLC12A2,CPEB4,RCOR3,SNAP25,TMCC1,SOX11,SP4,HECW1,KDM4C,TEX2,ZNF423,ARHGAP26,SPART,LMO3,POGZ,ITPRID2,SSTR1,LARP4,NKAIN2,SS18,ERBIN,ELOVL4,SEPT8,CEP68,TTBK2,SYNE2,ANKRD12,ADGRL3,TCEA1,TCF4,SATB2,RPGRIP1L,TCF12,CLASP1,PUM2,DICER1,ZFPM2,SLC44A1,NACC2,ERCC6L2,R3HDM1,KAT6B,TRPS1,EIF4ENIF1,UBE2H,UBE3A,GORASP1,FLRT2,ZBTB14,ZIC2,ZNF711,TMEM237,SMARCAD1,WNK3,PDSS2,RGS7BP,TIGD6,SOCS4,CPNE4" MicroRNA hsa-miR-633:mirSVR_highEffct hsa-miR-633:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.62E-104 9.07E-101 3.41E-103 3.14E-102 270 1550 "KCNH8,ACADM,ABHD6,KLHL32,TMEM132B,GALNT13,PWWP2A,KIAA1211,INTS2,HFM1,C1QTNF3,SPARCL1,SMIM17,ABCD2,LRCH2,CCDC146,ADAM23,BMPR1B,NAE1,CALB1,CAMK2G,VXN,PRC1,KRIT1,CCNH,USP6,C1orf52,DGKI,LRRFIP1,COPB2,B4GALT6,NDST3,ABCG2,C4orf33,CNN3,AKAP6,COL4A5,SLC4A8,ABI3BP,AHCTF1,MYRIP,ZNF521,ZFP28,IGDCC3,CPS1,FAM171B,PREPL,HAPLN1,LRRC3B,APPL1,PNPLA8,CTH,CYBB,LONRF1,LIN54,KIAA0586,ZNF804A,MYEF2,RUSC2,KIAA0319,NR1D2,CPEB2,DTNA,E2F5,EDN1,RASGRP1,FSD1L,PHF20L1,MBNL2,KMT5B,DCTN4,VPS13B,EPB41,EPB41L2,LRRC17,DENND4A,NCALD,ZNF391,ANKMY1,F5,FAM198B,TMEM132C,DLC1,FCGR1A,OLFM1,MEX3B,PCYOX1,FLT1,ATP6V1H,ATP2C1,DLL3,MSANTD4,FYB1,CHL1,RAPGEF6,SYT17,DISC1,KIAA1841,PPARGC1A,HPGDS,SPIN1,KCNMB4,FERMT2,LNX1,STON1,PCLO,GRIA2,RNF165,ZBTB49,PSIP1,MAP4K5,RASSF8,ZHX1,FRMD5,TNFAIP8L3,MIER3,HLF,ELOVL5,GABARAPL2,HNF4G,HNMT,ZIC5,RBPJ,LRRCC1,INSM1,JAK2,KCND2,LAMP2,LIG4,MATN2,MATN3,MBNL1,LRP1B,SRSF12,MEST,MIA2,MKLN1,XRRA1,BLOC1S2,MSR1,NEK1,NF1,NFE2L2,NFIX,CNOT4,NOVA1,NRCAM,NTRK2,IGSF11,LOC100128398,OPRL1,GPR137C,GLIPR1L2,SLC10A4,SNX10,RETREG1,PLCL1,PCDH18,MAPKAP1,STRN3,LRP12,SEPT4,DRAM2,LRRN3,MAPK9,GDPD1,VPS13C,SNRK,CNTLN,MTMR10,ELOVL2,SPDL1,TMEM260,PTPRB,C1orf109,PTX3,CEP97,FAM66C,SH3TC2,FAT4,RAP1GDS1,ZNF532,TMLHE,ROBO1,ROBO2,RORB,NEK11,SPIN3,TRAPPC13,RMI1,SCN7A,SEC14L1,GALNT10,CHD9,FBXO11,CNKSR2,NLGN1,SEC31A,DZIP1,WDR37,CCDC88A,SLC14A1,MTERF2,BTBD7,LIMCH1,BDP1,KDM3A,UHRF1BP1L,MCF2L2,RBM26,LMO3,ITPRID2,NKAIN2,STAU1,ZSCAN29,ELOVL4,NEK4,TTBK2,KANK1,SULF2,NECAB1,PRRC2C,VPS13A,SYT1,COBL,ANKRD28,CAMTA1,TBCEL,SZT2,PCDHB10,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,TIAM1,BHLHB9,ERCC6L2,BEX4,NR2C2,STXBP4,TUBB1,UBE2H,UBE3A,P2RY12,WNT7A,SLC47A2,ZNF711,MICU3,ZNF74,ZNF184,EML6,EMSY,CADM2,LINC02210,STOX2,PRDM10,ADAMTS9,PLSCR4,EPM2A,MRPL47,CASC15,NHSL1,IFT88" MicroRNA hsa-miR-624*:mirSVR_lowEffct hsa-miR-624*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.85E-104 2.15E-100 8.07E-103 7.43E-102 243 1255 "ACADM,EMILIN3,KLHL32,ADCY6,ADD2,PLEKHH1,ALCAM,OGT,ANK2,LCORL,CADPS,CDK13,MARCH3,PCDHGB4,EIF4G3,STX16,RNF182,BBS2,DST,SGCE,GPC2,CALM1,PRC1,CCNH,SCARB1,L3MBTL4,CHN2,B4GALT6,LHX2,QKI,IGLON5,ARHGEF6,IQCK,AHCTF1,PREPL,AKAP12,HINFP,ANKRD44,CSF1R,LRIG1,RIMS4,PDE4DIP,FAM169A,CTH,DCAF4,CCDC144A,BOC,DOCK4,HDAC4,TM9SF4,TMEM170A,DBI,DDX46,ALKBH8,PLPPR4,SNAP91,DYNC1I1,CPEB2,DNAJB6,E2F5,EBF1,HIPK3,SEMA3D,YAF2,PHF20L1,TENM1,ERCC2,ETV1,ANKMY1,GMPR2,NRN1,F5,FAM198B,TAOK3,DLC1,FCGR1A,ST3GAL6,CEP78,FKTN,ZSCAN30,ZNF589,FGFR1,SUCO,FOXO3,ANKFY1,PDLIM5,FAM49B,KHDRBS3,CGREF1,SARAF,SIGLEC8,DISC1,GATM,NEU3,TUBGCP4,MSTN,PPARGC1A,BRD8,GPR34,GRIA2,PLCD4,FAM19A2,RABL2A,ATOH8,MIER3,VSIG4,ELOVL5,HNF4G,SMAP1,ZNF678,ITPKB,STXBP5,LAMP2,SYTL4,ZFYVE27,CHIC1,LRP1B,ZNF680,MYO9A,ZC3H12B,NDP,OPA1,PCDHGC3,PCDH9,PCSK5,PDE4A,GPR85,GNG2,SEMA5B,SNX10,XRN1,PLCL1,LRP12,ING3,MINDY2,PPP2R2C,PPP2R5E,KANSL1,TMEM104,CNTLN,MTMR10,ZIK1,PTPRN2,PEX2,ACSM5,ZSCAN2,TUG1,CEP97,RAD51D,SH3TC2,FAT4,ROGDI,GTDC1,ZDHHC4,MRPS18A,SLC25A36,RIC8B,ZFHX4,ROBO2,RORB,MRAP2,ZC3H14,ATP8B4,ADAL,ABCA11P,HSD11B1L,RTN1,RMI1,SEMA6D,ATXN7,PRCD,CPEB3,CHD9,CNKSR2,DZIP1,DHX30,PKNOX2,NAPB,RCOR3,ANKRD36,MYO16,KDM3A,NMNAT2,TEX2,PEG10,DBNDD2,ERBIN,ZSCAN29,NEK4,CEP68,SULF2,SEPT3,NSFL1C,ARHGEF9,COBL,CAMTA1,KLHL4,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,USP32P1,SIK3,ZFPM2,NR2E1,SYNPO2,AMACR,STXBP4,DCBLD1,TSN,TSC1,TTTY15,HIRA,UGT8,FLRT2,VIPR2,RICTOR,ZIC1,ZIC2,ZNF24,KCNT2,TRIM9,LYPD6,EML6,EMSY,EVI5,HPS4,ITM2C,FAM13C,MRPL47,DOCK8,ACTR3B,FAM219B,MSRB3" MicroRNA hsa-miR-195:mirSVR_highEffct hsa-miR-195:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.46E-104 2.50E-100 9.31E-103 8.57E-102 258 1420 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,ACTN1,GALNT13,AXIN2,ADRB2,DPY19L2P4,AP2A1,SRPX,CEP126,ARHGAP20,OGT,ANK2,BCAS1,PPFIA3,LGR5,CDC14B,CASK,STK33,ZBTB10,CCAR2,TTLL9,MPDZ,RGS9,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,CA8,CACNA1B,KALRN,PTBP2,CAMK2G,RUNX1T1,ARHGEF1,CFL2,CHRNA4,PPT2,CLCN3,QKI,SLC4A8,ABI3BP,TBPL1,MYRIP,ZFP28,PREPL,HAPLN1,CRYM,LRIG1,SOCS5,ERC2,USP6NL,ARHGAP32,KATNAL2,RIPOR2,DCAF8,KCTD8,IST1,IP6K1,GIT2,ARMCX2,YTHDC1,JAKMIP2,MYEF2,SPOCK3,DNM1,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,RASGRP1,PHF20L1,EGFR,MBNL2,PLEKHA1,DENND4A,CEP85L,SPEG,EYA1,NRN1,ACSL4,FGFR1,PRKAG2,SUCO,RGPD5,SLC37A3,PDLIM5,CSPG5,NSG1,GALNT15,DISC1,SESN1,USP19,PCDH17,GHR,SPIN1,FERMT2,GPD2,PCLO,RNF165,RASSF8,ZHX1,FRMD3,MIER3,SHISA6,MSL1,RBPJ,NIM1K,INPP1,NME9,SLC35G1,KCND2,KIF2A,KIF5A,LAMP2,PACRG,MAP4,MAP6,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,THYN1,RTL5,NDP,NOVA1,SLC11A2,NTRK3,CNTN3,ETFRF1,PCDH9,PIK3R1,JAKMIP1,PSAT1,SDK2,MAGEL2,RETREG2,EPB41L4B,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,PIGG,CNTLN,PTCH1,STK32A,ZSCAN32,PTPRD,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,ZDHHC14,RDX,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,ARMH4,FBXW7,ABCA11P,KCNIP1,ZNF568,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN8A,COPZ1,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,ANKRD6,FAM81A,ARHGEF40,KBTBD4,SLC22A4,ZFP1,RCOR3,SNAP25,MBD5,SNRPN,UNC5B,ZC3H13,TSPYL2,NFASC,LMO3,RGL1,PRRC2C,SYNE2,VPS13A,SYPL1,COBL,C12orf76,TBCEL,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,TMEM9,ERCC6L2,KAT6B,TP53BP2,TPM2,RUNDC3B,LGI4,ZNF708,TRIM9,NDRG4,REEP1,FSTL5,EML6,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,RNF170,SNX14" MicroRNA hsa-miR-490-5p:mirSVR_lowEffct hsa-miR-490-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.53E-104 2.53E-100 9.42E-103 8.67E-102 269 1545 "NCKAP5,ACTN1,ADD1,ADORA1,ADRA1D,ADRB2,HECW2,KLHL13,PCDH19,CC2D2A,SMIM17,SEMA6A,AMPD2,LCORL,PPFIA4,PHF12,EPB41L5,NUMB,DYNLL1,TMEM108,N4BP2L1,CFLAR,BMP7,SYNJ1,SGCE,WASF1,KALRN,PTBP2,CAMK2B,VXN,LDB2,METTL6,CD38,SEPT7,DLGAP1,SRSF11,CHN1,CLCN3,MYL6B,AKAP5,GDA,CSF1,RGS6,LRRC3B,CSNK1E,SLITRK5,DZIP3,APPL1,PLCXD3,CTH,RIMS2,DCAF4,USP6NL,SEC14L5,CCDC144A,CYBB,GAPVD1,ZFYVE16,MATR3,KIAA0586,IST1,DAPK1,SPOCK2,IP6K1,SPATA2,YTHDC1,HEPH,DDX46,SV2B,WDR20,RPS6KL1,CDON,DOCK2,CASP8AP2,DPP6,DNAJB6,ABCC5,DNM1L,EBF1,YAF2,EGFR,MBNL2,EGR3,EIF4G2,C3orf18,C8orf37,STX2,ZNF549,CDKL3,EXTL2,MRVI1,CEP78,FECH,FGFR1,BAIAP2,SCARA3,HPCAL4,IP6K2,SLC37A3,EFCAB2,RASL10A,ERGIC3,GABRG2,GAD1,SIGLEC8,DISC1,GATM,IGSF5,ALDH1L1,HPGDS,RAB30,MAP7D2,GPD2,PRUNE2,TDRKH,CCDC184,PCLO,FAM19A2,RABL2A,GUCY1B1,IRAK3,UBE2QL1,PADI2,FRMD3,HNMT,ZDHHC15,SHISA6,IRF8,C2orf72,RBPJ,LRRCC1,NME9,ITPKB,KCNN2,IPO5,LIG4,NCOA7,PIK3AP1,CLEC18A,MAN2A2,CHIC1,MEF2C,MEIS1,KITLG,SCAMP5,MID1,ZNF680,GIT1,MXI1,MYO9A,ZC3H12B,NEK1,OCRL,GLIPR1L2,CNTN3,DPY19L2P2,PCDH9,PDE4D,PDE1B,PFKFB4,PIK3R1,PLCL1,PURG,PRIMPOL,LRP12,MAGEL2,POU6F1,MINDY2,KANSL1,PRKACB,CEP41,PKIA,MAPK9,PTPRB,TUG1,CEP97,ZNF793,SUSD4,OXR1,RASGRF2,KHDRBS2,CRTAC1,REV3L,RNASEL,CCDC82,DCUN1D2,PNMA8A,NEK11,RPS6KA2,S100B,DGLUCY,SEMA6D,CSRNP3,SCN2B,SCP2,TNFRSF19,CASC3,FOXRED1,PPM1E,BTBD3,SLC8A1,ARHGEF40,KBTBD4,SLC12A2,BTBD7,GKAP1,MAST1,SMARCD3,SNAP25,SNRPN,MYO16,HECW1,ERC1,PEG10,SPART,NFASC,ATP10B,ZSCAN29,NEK4,SEPT8,CEP68,JMJD6,PLCB1,SYN2,SYPL1,SLC37A2,TACC1,TACR1,TAF9,ADGRL3,RPGRIP1L,TCF12,CLASP1,SZT2,SYNE1,FRYL,SIK3,TEK,DICER1-AS1,AP4E1,GPR161,SLC44A1,ERCC6L2,RIMBP2,CDK20,WBP2,STXBP4,ZKSCAN5,SGK3,TUBB1,CCDC14,VLDLR,WIPF1,CLIP2,GUSBP1,ZIC1,ZIC2,ZNF28,TRIM9,LYPD6,REEP1,POLR3H,FSTL5,SLC30A3,HPS4,EPM2A,MARCH8,MSRB3,CPNE4" MicroRNA hsa-miR-29b-1*:mirSVR_highEffct hsa-miR-29b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.91E-104 3.31E-100 1.23E-102 1.13E-101 283 1711 "ASPHD1,ACADM,KDM5D,PWWP2A,BEND6,DPY19L2P4,AP2A2,ZNF608,MTUS1,HECW2,TXNDC16,SMIM17,ABCD2,LTBP4,UNC79,FAM135A,ZNF687,ZFAT,OGT,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,UPRT,SFMBT2,ATP1B3,STX16,RNF182,RGS11,RGS9,CACNA1B,VXN,CAST,RUNX1T1,CCNH,MAGI1,DIS3L,SOCS6,MAP4K4,CNGA3,FAM149A,AKAP6,RCHY1,COX4I1,CNRIP1,SLC35F1,CPS1,ANKRD44,GDA,SNCAIP,SOCS5,CNTNAP2,UBXN2A,PHF14,CTH,PUM1,DCAF4,CCDC144A,CYBB,SNPH,ZFYVE16,IST1,DBI,AIF1L,ARMCX2,HS3ST2,NR1D2,DTNB,ABCC5,E2F5,EBF1,SEZ6L2,WDPCP,EDNRA,TMTC1,FAM13A,PHF20L1,EGR3,AASS,GOLGA7,KCTD3,CALCRL,PAN3,COQ7,RCAN2,SRRM1,DENND4A,NCALD,TLR7,EZH1,F5,CEP78,FDFT1,GORAB,MED12L,UBE2E3,SEC23B,AGAP3,RGPD5,SLC37A3,NELFCD,NBEA,APOPT1,UFM1,OGA,GABBR1,TRAF3IP2,ZNF274,ERAP1,DISC1,KIAA1841,CPLX1,TUBGCP4,SULT1C4,AHDC1,ADAM28,USP19,MALT1,RUNDC3A,COPS8,SPIN1,TNRC6A,DCLK2,GPD2,TMEM121B,GRIA2,PLCD4,ZBTB49,FICD,RASSF8,HAS2,TOX2,ELOVL5,HMGCR,NEGR1,NKD1,KCNK3,KCNN3,KIF2A,HECTD2,NCOA7,MARK1,MAT2A,MBD1,TM6SF1,MEST,KITLG,MITF,MKLN1,XRRA1,ZNF680,ADAM22,NCF2,NEFM,NEFH,CCDC13,NF1,CNOT4,NPR2,SLC11A2,NTRK2,PRTG,ENPP2,SLC10A4,OLA1,ZNF655,KCTD15,PLCL1,STRN3,EXOSC10,EPB41L4B,FA2H,POU6F1,MINDY2,TATDN3,PPP3CA,PKIA,MAPK9,MAPK10,GRAMD1C,VPS13C,SNRK,QRICH1,MTMR10,TMEM260,PTPN13,TTC13,PID1,TMEM255A,CCDC40,ZNF493,RASGRF1,RASGRF2,RET,GTDC1,FIGN,RFX2,SLC25A36,RIC8B,PBRM1,ZNF532,SETD5,C12orf49,CARF,ROBO1,ROBO2,ELP2,RPE,FBXW7,KIAA0895L,ATP8B4,GLDN,ADAL,LRRK2,MEG3,ABCA11P,KCNIP3,CCDC112,LRFN5,FNIP1,TNFRSF19,CPEB3,SHC4,HKDC1,CHD9,SLA,SEPHS1,MBD5,CABCOCO1,SNRPN,SP2,SP4,PEG10,NXT2,ZSCAN29,NEK4,SEPT8,DIP2A,KANK1,NSFL1C,VPS13A,SYT1,ANKRD28,ANKRD12,MTCL1,IQCE,SATB2,TCF12,PCDHB3,GPRIN3,FRYL,DICER1,SIRT1,ITGB3BP,AKTIP,HEY1,BHLHB9,KAT6B,NPL,TTTY15,UCHL1,GORASP1,PLEKHH2,TBC1D15,RBFOX3,WIPF1,ZNF138,REEP1,SPIRE1,EMSY,PRTFDC1,RNF103,ADAMTS9,SIGLEC10,NAV3,PLSCR4,PDSS2,KAT6A,PHTF2,ADAMTSL3,NETO1,JPH3" MicroRNA hsa-miR-4326:mirSVR_lowEffct hsa-miR-4326:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.78E-104 3.79E-100 1.40E-102 1.28E-101 282 1700 "RALGAPA1,SYS1,ACTN1,NDRG3,ADCY6,TMCC3,ADRA1D,BEND6,ZNF608,ADGRF5,UNC79,FAM135A,AMPH,CCDC146,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,APBA2,APOC1,VAT1L,USP37,ZFYVE28,NCOA1,CCAR2,TMEM108,ATP1A1,EIF4G3,N4BP2L1,LINC00847,BMPR1B,SYNJ1,SYNJ2,SCAPER,CASTOR3,MTMR3,MTMR2,GYG2,CACNA1A,KALRN,ISPD,SPAG9,NFS1,USP6,RGN,DCLK1,LOC730101,CCPG1,CACNA2D2,LHX2,RAB28,NRXN3,CLCN3,FBXO7,ABCG2,TMEM184B,CNR1,AKAP7,AKAP6,TBPL1,ZNF521,NRG2,GDA,VCAN,KIAA0040,RUBCN,DOCK4,RIPOR2,SNPH,LONRF1,TBC1D5,DGKG,BRINP1,RUSC2,DDX46,WDR20,DLX1,NYAP1,MED12,DPYSL2,PDCD6IP,DNM1L,CNNM1,RASGRP1,TMTC1,CELSR3,PHF20L1,MRO,EGR3,TENM1,RABEPK,NCALD,REEP2,CLVS1,NSRP1,CEP78,FCGRT,PRMT5,ZNF589,SEC24B,OLFM1,AMOTL2,VTI1B,SLC37A3,HVCN1,GABRG1,TRAF3IP2,RAPGEF6,ERAP1,ZNF559,DISC1,SEPT9,ACSS1,GCNT2,PPARGC1A,GLI2,ZNF638,DCLK2,ZNF782,GPT2,C1QL4,ADAMTS13,GRIN2C,GRM8,CIT,RNF165,KAT7,SOX21,MAP4K5,UBE2QL1,ARHGAP36,HMGCL,AGBL5,SHISA6,FAM95B1,IGF1,LRRCC1,SCIN,IL6ST,IL12A,KCND1,KCNH2,KCNJ16,KPNA5,TTYH2,SFXN5,LIMS1,PAXBP1,HECTD2,CLEC18A,MARK3,MATN2,MBNL1,LRP1B,MEIS2,KCTD6,MID1,MMP16,MSR1,MYO5A,P2RY13,NEFH,NEK1,NME4,NUCB2,GLIPR1L2,PCDH8,CDK18,ENPP2,GNG2,PFKFB3,OLA1,PIK3C2A,SNX10,RETREG1,PLCB2,JAKMIP1,SEPT4,POU6F1,PPP1R1A,RASGEF1B,PRKACB,PKIA,PRKCB,HYDIN,MASP1,DEF8,WDR25,PIGG,PTN,ACSM5,TMEM231,ROGDI,RBBP6,KHDRBS2,RGS12,SLC25A36,RIC8B,PBRM1,SETD5,ALG9,ARMH4,LRRK2,NCBP3,RMI1,DGLUCY,SCP2,PEAR1,FAM102A,SH3GL3,KIF16B,FNDC3A,NLGN1,SLA,FAM214B,SLC9A5,ELMO2,ZFP1,GKAP1,CDK5RAP2,MYH15,LIMCH1,MBD5,ZNF415,TRERF1,BDP1,FNBP1,MYCBP2,KDM4C,SAMSN1,TTBK2,SULF2,SYNE2,PLCB1,SYPL1,PDLIM2,FBXW11,TCF4,CUX2,ZEB1,SYNE1,NAT16,PCDHB3,PUM2,FAM200B,DICER1-AS1,ITGB3BP,ARL10,NR2E1,ERCC6L2,TMPO,FAM124A,R3HDM1,TPM1,NPL,TPM2,ZNF346,RUNDC3B,AMACR,STXBP4,TSC1,UBE3A,OSBP2,TBC1D15,XRCC4,ZIC2,ZNF24,ZFP41,CELF4,TMEM198,UPF3A,EVI5,ADAMTS9,CIAPIN1,URM1,TRIM16L,FAM13C,RTN4,KAT6A,RNF170,RNF146,SOCS4,LAS1L" MicroRNA hsa-miR-4329:mirSVR_lowEffct hsa-miR-4329:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.78E-104 3.79E-100 1.40E-102 1.28E-101 288 1772 "VWA5B2,ABCF1,ASIC1,ACHE,AS3MT,NDRG2,KLHL32,ADD1,KIAA1211,OSBPL1A,WDR35,ALCAM,CDC42BPA,DPP10,FGD2,SUGT1P4-STRA6LP-CCDC180,USP37,CPNE5,CDC14B,PRX,CASK,ARHGDIA,PLA2G4C,MARCH3,PCDHGB4,SLC4A4,ZNF583,DOCK11,ADGRB2,RGS11,CFLAR,KSR1,ARHGEF7,AP1M1,GPC2,CA8,PTBP2,VXN,CCNH,CBFA2T2,CD38,DLGAP2,CLCN3,QKI,SULT4A1,CNGA3,CNN3,AKAP6,SUMF2,COL9A1,MYRIP,ZFP28,SEC31B,PREPL,C2CD2,SUSD5,CNTNAP2,CST3,SLITRK5,PHF14,CCDC144A,CYBB,BOC,HDAC9,GPRASP1,EARS2,TBC1D5,INTS1,IST1,SPOCK2,PITPNC1,C2CD2L,GSDME,POM121,FAM107B,ZNF582-AS1,RAB39B,DYNC1I1,ACOT8,DUSP9,MAMLD1,ABCC5,E2F5,AASDH,HIPK3,CNNM1,KLHL5,PHF20L1,MBNL2,EGR3,CALCRL,CDKL3,RRAGB,FCGR1A,FKTN,STRADA,FGF12,PRKAG2,PCYOX1,NBEA,HVCN1,STAMBP,FYN,MEGF10,CHL1,GABRB3,RAPGEF6,ZNF274,TMEM8B,KIAA1841,GCNT2,GFER,MALT1,MSL3,ZNF638,POLL,GPR12,CCDC184,STMN2,ADAMTS13,FAM19A2,FAM107A,RNFT2,MUM1,IRAK3,SYNPO,HMGCR,MSL1,FAM95B1,NKD1,GAREM2,ITPKB,SLC35G1,CREG2,KIF5A,KIFC3,TTYH2,NCOA7,GPR155,MAN2A2,ZFYVE27,MAT2A,MEIS2,MIA2,KITLG,MID1,MXI1,LYRM9,MYO6,NBL1,CCDC13,NFIX,VWA2,DNHD1,SLC11A2,NUCB2,LOC100128398,P2RY1,PCDHGC3,PCSK5,OLA1,PLCB2,JAKMIP1,SLC25A23,MTRF1L,PURG,MAPKAP1,SDK2,MBOAT7,POU6F1,PPP2R2C,MAPK9,RELN,SNRK,PTK2,PTPRO,ZSCAN2,NKAIN1,QDPR,ACSS3,FAM66C,TRIM68,RET,RGS3,RGS12,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,EXD2,GSTCD,CYB561D1,ROBO2,NEK11,ARMH4,ZC3H14,TCP11L1,LRRK2,RPS20,ABCA11P,S100B,SATB1,ATXN2,SCN8A,SCP2,SUPT20H,SH3BGR,SH3GL3,ASAP3,MYO18A,NLGN1,FAM214B,SLC8A1,NAPB,DMRTC1,ANKRD36,FAM219A,HECW1,NFASC,ITPRID2,SSTR1,ZC4H2,ST5,ADHFE1,STX1A,KANK1,STXBP1,PRRC2C,SYN2,TAF6,EXOC7,DNMBP,ADGRL3,SMG6,KLHL4,MGRN1,WSCD1,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SLC19A3,GPRIN3,ZFPM2,AKTIP,TMEM9,RELL2,BHLHB9,RIMBP2,TP53BP2,NPL,TRIO,STXBP4,TRPS1,RUSC1,CA14,RPL7L1,XRCC4,ZIC2,KCNT2,REEP1,TMEM198,SPIRE1,LAMP5,SMARCAD1,EMSY,PRTFDC1,PLSCR4,FZD3,DOCK8,ST7,MARCH8,FBXO36,ADAMTSL3,JMJD1C,RNF170,NETO2,LAS1L,SENP7" MicroRNA hsa-miR-221:mirSVR_lowEffct hsa-miR-221:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.53E-104 4.77E-100 1.75E-102 1.61E-101 267 1526 "NCKAP5,SYS1,TMEM132B,TMCC3,ADD2,PTCHD1,BEND6,OSBPL8,CC2D2A,CEP126,BBOX1,LRCH2,SEMA7A,LCORL,PHF12,PKP4,TMEFF1,STK33,INSYN2B,ATP1A1,SLC4A4,KSR1,SYNJ1,ARHGEF7,SCAPER,GYG2,CALM1,CD38,CDH2,LARGE1,CHGB,CHN2,NRXN3,FBXO7,CNN3,FAM149A,AKAP6,ABI3BP,SMARCAL1,ZNF521,CNRIP1,ZNF385A,CPS1,RBM39,CRHBP,CRY2,ANKRD44,NCOR1,GDA,CSF1,ARHGEF10,OSBPL3,SUSD5,SOCS5,SLITRK5,UBXN2A,PLCXD3,MATR3,MAML1,BRINP1,YTHDC1,DGCR5,KIAA0319,DDX46,SGSM2,DLX1,DYNC1I1,CDON,DMTF1,CASP8AP2,DNAJB6,DNM1L,E2F5,WDPCP,HIPK3,RASGRP1,KLHL5,YAF2,FAM13A,EIF5,EIF1,STX2,ERBB4,DENND4A,RRAGB,EZH1,FAM198B,TMEM132C,CEP78,FKTN,STRADA,GTF2IRD2,FGF14,SCARA3,UBE2E3,MEX3B,SYNCRIP,FLT1,SLC37A3,STAMBP,ATP2C1,CGREF1,GABRG1,IGSF5,RUNDC3A,TCERG1,RNPS1,TNRC6A,ZNF638,GNAO1,PRRC2B,PRUNE2,GPR12,GRB10,PLCD4,CIT,RNF165,ZHX1,FRMD5,HNF4G,ZDHHC15,NEGR1,AGFG1,SHISA6,IGF1,METTL21A,KCNJ16,KCNQ3,CREG2,IPO5,CYP27C1,MAP6,ADAM11,MEF2C,MEST,KCTD6,MID1,MITF,AFF1,MMP16,COL28A1,ZNF862,CNOT4,NRCAM,NTRK2,ZNF713,DPY19L2P2,ETFRF1,PCDH8,PCDH9,PCSK1,OLA1,PIK3R1,ZNF655,CCSER2,PRIMPOL,LRP12,KANSL1,PRKAB2,HYDIN,DIRAS2,GDPD1,CNTLN,PTK2,PTPRB,C1orf109,PTX3,TUG1,PID1,USP47,ENOX1,RBBP6,RBBP8,MSANTD2,REV3L,GTDC1,FIGN,RFX2,RGS12,LGI2,TMLHE,C12orf49,NEK11,RTN1,SEMA6D,SATB1,FOXRED1,KIF21A,ST6GAL1,ST8SIA1,FAM81A,SLC6A11,SEPHS1,SLC11A1,ATF7IP,ANKRD36,SNAP25,KIF13A,SNRPN,MYO16,USP33,BDP1,SOX11,KDM3A,SPP1,CDK19,PBLD,CLASP2,ITPRID2,NEK4,SEPT8,RGL1,STX1A,SULF2,PLCB1,SYPL1,SYT1,COBL,TACC1,TACR1,ANKRD12,DNMBP,ADGRL3,KLHL4,CUX2,TRIM2,NAT16,GPRIN3,FRYL,CCDC173,SIK3,RNF216P1,PMS2CL,DICER1,SIRT1,C18orf54,GPR161,TIAM1,CSMD1,KAT6B,UGT8,ZNF781,CLDND1,XRCC4,ZBTB14,ZNF74,TMEM237,AMZ1,ANKS1B,SPIRE1,ZFAND5,EMSY,MFF,STOX2,PRDM10,ADAMTS9,FAM47E,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,FAM219B,RSPRY1,TRAM2-AS1,SOCS4,SENP7" MicroRNA hsa-miR-211:mirSVR_highEffct hsa-miR-211:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.82E-104 4.93E-100 1.80E-102 1.66E-101 272 1584 "KCNH8,XKR4,NDRG3,KLHL32,CCDC85A,GALNT13,ADD2,ADORA2A,PWWP2A,ESYT2,AP2A2,INTS2,MTUS1,TAOK1,ADGRF5,C1QTNF3,SEMA6A,SPOP,ALCAM,BIN1,ZFAT,UPRT,SEMA4G,SPTBN4,RGS20,MARCH3,TTLL9,SEC11C,RGS9,C5,KALRN,CCNH,MTMR7,CDH2,L3MBTL4,CFL2,SOCS6,CHN2,PLAA,TPP1,CLTC,ARMC8,AKAP6,COL4A5,AHCTF1,BAG4,ZNF521,ZFP28,RBM39,HAPLN1,RNF14,GDA,TRIM69,SUSD5,VAC14-AS1,DZIP3,ERC2,RUBCN,CCDC144A,CYBB,BOC,HDAC9,GAPVD1,TCAF1,DCAF8,CENPL,LONRF1,DGKG,TMEM170A,DAPK1,DBI,ARMCX4,ARMCX2,DGCR5,TIAM2,FBXL5,DDX46,RHOBTB1,PLPPR4,SPOCK3,FAM107B,ZNF582-AS1,CHRDL1,GRIN3A,DMD,HS3ST2,DMTF1,SLC12A6,PDCD6IP,RCAN1,DTNA,FRY,CELSR3,APH1A,KMT5B,RASA4,GOLGA7,C8orf37,EPHB1,RABEPK,SRRM1,SIRPB1,RPS6KC1,ACSL4,SCML2,FER,FGFR1,POLK,SUCO,ATP13A4,SLC37A3,COQ5,NBEA,SMC2,RASL10A,ATP6V1H,ZNF605,KHDRBS3,NSG1,STAU2,GABRG1,GABRG2,ZNF274,ERAP1,C15orf41,LRRC37A6P,GCNT2,GDF9,PCDH17,GGT7,PPARGC1A,TOX3,ZNF638,RAB40B,GPT2,FUT10,GRIA2,MAP4K5,IRAK3,RASSF8,HAS2,GABARAPL2,SMAP1,IRF8,LRRCC1,INSM1,JAK2,SLC35G1,KCND2,STXBP5,SYTL4,HECTD2,NCOA7,ZFYVE27,MAT2A,MBNL1,MEIS1,MGAT3,MMP16,NOVA1,NTRK2,PCDH9,PDE4A,PDE4B,PDE4D,TMIE,FAM218A,RETREG1,XRN1,GPSM2,SMIM7,LRP12,SEPT4,POLR2F,MAPK9,VPS13C,GDPD2,SNRK,PIGG,SPDL1,PTPRD,EML5,PTPRE,C1orf109,PTX3,PID1,CEP97,TMEM255A,USP47,CCDC40,ZNF793,ZDHHC14,GTDC1,RIC8B,ZFHX4,CARF,GSTCD,CCDC25,FBXW7,TCP11L1,KCNIP3,ATXN2,FNIP1,ARX,FERMT1,KIF16B,SHC4,FHOD3,KANSL3,BTBD7,MYH15,RCOR3,MBD5,KIF13A,CMTR2,SNRPN,TRERF1,MYCBP2,KDM4C,ZNF423,ZC3H13,ATP10B,ZC4H2,SS18,ZSCAN29,ELOVL4,RGL1,SYPL1,TACC1,ANKRD12,PJA1,CAMTA1,DNMBP,TBCEL,TCF4,SATB2,ZEB1,TCF12,SZT2,SYNE1,FRYL,SIRT1,GPR161,ERCC6L2,TMPO,NPL,RPL7L1,FLRT2,PLEKHH2,VSNL1,ZNF781,GUSBP1,XRCC4,CFAP298,MICU3,REEP1,TMEM237,EMSY,STOX2,PRDM8,TMEM178A,VPS35L,GAL3ST3,WNK3,PLSCR4,RGS7BP,DOCK8,ST7,FBXO36,RNF170,NETO1,JPH3" MicroRNA hsa-miR-485-3p:mirSVR_highEffct hsa-miR-485-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.59E-104 5.37E-100 1.95E-102 1.80E-101 249 1325 "NCKAP5,KLHL32,CCDC85A,AGT,HACE1,OSBPL6,WDR35,CC2D2A,SPARCL1,ARHGAP20,ALK,DPP10,SEMA7A,UPRT,PPP4R4,CASK,NUMB,TMEM108,SLC4A4,RNF182,ADGRB3,SEC11C,CFLAR,SCAPER,CACNA1B,RUNX1T1,LDB2,ZMYM4,MAGI1,RCBTB2,SRSF11,C4orf33,QKI,TMEM184B,CNR1,AKAP6,MYRIP,ZFP28,PREPL,CREM,CRHBP,GDA,CLIP3,VCAN,PDE4DIP,APPL1,PHF14,GAPVD1,RIPOR2,SNPH,HDAC4,LIN54,DAPK1,ZBTB24,HEPH,KIAA0753,ZC3H11A,SGSM2,CHRDL1,NR1D2,PDCD6IP,DTNB,GOLT1B,EDNRA,ANKRD46,YAF2,FAM13A,MRO,TENM1,TMEM35A,CALCRL,EPB41L2,STX2,ABCA8,SCML2,DLC1,CEP78,GORAB,FGF1,FGF13,FGFR1,BAIAP2,UBE2E3,RGPD5,PSD2,EFCAB2,JKAMP,NBEA,MPP6,ZMAT1,MEGF11,GABRG2,GAD1,GALC,ZNF274,ZNF559,C15orf41,NEU3,SRCAP,ARFIP1,PPARGC1A,COPS8,TOX3,TNRC6A,ZNF638,RAB40B,GPD2,STMN2,GRIA2,KAT7,BACH2,HNF4G,NEGR1,SMAP1,ZNF181,LRRCC1,INPP1,KCNN2,LIG4,SYTL4,HECTD2,MATN2,MATN3,MEIS1,MEIS2,AFDN,MSR1,N6AMT1,MXI1,MYCN,ZC3H12B,NFIX,CHAMP1,OGG1,LOC100128398,CLDN11,P2RY1,CNTN3,DPY19L2P2,PDCD2,GPR85,GNG2,PFKFB2,ABCB1,PIK3C2A,PCDH18,PURG,PSAT1,EPB41L4B,PPM1B,PRKAB2,PKIA,PRPSAP2,GDPD1,VPS13C,CNTLN,MTMR10,PTPRD,PTPRG,CEP97,TMEM255A,RAD51D,FAM184A,ZNF493,RBBP6,ERI2,MORC4,GTDC1,FIGN,RFX3,UBR7,RGS12,RNASEL,CCDC82,ZNF532,TMLHE,CARF,ROBO2,PCMTD2,BAALC,SPIN3,LRRK2,HUNK,ZNF568,KIF21A,AMBRA1,EPN2,KANSL3,SLC6A11,SLC8A1,LGI3,LIMCH1,MAPKBP1,CMTR2,SNRPN,PDZD2,DOK5,ZC3H13,RBM26,ZNF302,NKAIN2,NEK4,SEPT8,PRRC2C,SYNE2,VPS13A,SYPL1,TACR1,MTCL1,PJA1,MLST8,DMXL2,ZEB1,TRIM2,PCDHGA11,SYNE1,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,AP4E1,PPIL6,TSC1,SGK3,FAM155A,UGT8,PLEKHH2,VLDLR,TBC1D15,XRCC4,ZIC2,ZNF19,ZNF540,EML6,ANKS1B,ZFAND5,LINC02210,TMEM178A,HNRNPA3,PHTF2,ACTR3B,RNF146,ZNF30" MicroRNA hsa-let-7g*:mirSVR_highEffct hsa-let-7g*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.89E-104 5.53E-100 2.00E-102 1.85E-101 238 1207 "RALGAPA1,DGCR6,KCNH8,CLK4,KLHL32,AXIN2,ADRA1D,BEND6,HECW2,OSBPL1A,TBC1D14,SPARCL1,ABCD2,PCDH10,UNC79,FAM135A,SYT13,OGT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PHYHD1,BCAS1,CHRD,RASL11B,ATP2A2,ADGRB2,BCHE,NRP2,SYNJ1,MTMR2,IL33,KALRN,PTBP2,AP4M1,LRBA,MAGI1,SRSF11,CHN2,NDST3,LHX2,LY86,AKAP7,IQCK,LETMD1,AKAP12,HAPLN1,CS,LRIG1,SOCS5,PDE4DIP,SLITRK5,USP6NL,HDAC9,TCAF1,KIAA0586,IST1,IP6K1,ALKBH8,SNAP91,DLX1,HS3ST2,DNAH9,NR1D2,CDON,CPEB2,DTNA,ABCC5,E2F5,EBF1,WDPCP,EDNRB,PHF20L1,MBNL2,EGR3,PLEKHA1,RGS17,GPHN,CEP85L,EYA1,CLVS1,DLC1,CEP78,FGF13,SYNCRIP,SLC37A3,DCTN2,C2orf88,NBEA,HVCN1,STAMBP,CAMKK2,CSPG5,MEGF11,ZNF559,KIAA1841,AHDC1,PPARGC1A,GLI2,KDM2B,GNAL,FERMT2,GRB10,DIDO1,C1QL4,ZNF496,CIT,KAT7,LINGO1,ARHGAP36,BACH2,ZNF491,SHISA6,SMAP1,SOWAHA,KNDC1,INSM1,METTL21A,KCND2,KCNH2,KCNJ16,STXBP5,LAMP2,NCOA7,LSS,ASPRV1,MAP4,MBNL1,SHC3,HS6ST3,NCF2,NPTX1,NTRK2,NTRK3,CLDN11,PCDH8,PCSK1,PCSK5,ENPP2,NLGN3,PIK3C2A,ZNF655,FAM218A,ZFYVE21,ING3,TATDN3,SAMD9,SNRK,PTK2,TMEM260,USP47,RASGRF1,REV3L,PRIMA1,SLC25A36,PBRM1,ZFHX4,SNX22,NEK11,MAP6D1,MEG3,TRAPPC13,RMI1,SALL1,SGK1,ARX,KIF16B,CPEB3,FNDC3A,SYBU,ANKRD6,WDR37,SLC22A4,SNCA,MBD5,SNRPN,KDM4B,PDZD2,KDM3A,MYCBP2,ATP10B,CLASP2,TROVE2,ZNF302,ZC4H2,LARP4,NKAIN2,ERBIN,STAU1,NSFL1C,NUDT10,DNAJC9,PLCB1,MMS19,CAMTA1,TAL1,FAM208A,ADGRL3,ZEB1,DOCK9,FAM189A1,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SLC44A1,TMPO,R3HDM1,KAT6B,RGMB,TRIO,EIF4ENIF1,PLEKHH2,BCL2L13,VLDLR,ZIC2,MKRN3,ZNF142,REEP1,EMSY,MDH1B,NAV3,PCBP4,MPPE1,PDSS2,FAM13C,KAT6A,FBXO36,FAM219B,JMJD1C,FXR1,NETO2,SENP7" MicroRNA hsa-miR-1272:mirSVR_highEffct hsa-miR-1272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-103 5.76E-100 2.08E-102 1.91E-101 272 1585 "RALGAPA1,AS3MT,KIAA1211,PTCHD1,SLC24A4,MTUS1,HACE1,ARHGAP20,DPP10,LRCH2,ANK2,LCORL,PARG,APAF1,APC,UPRT,AQP6,ARNTL,CDK13,PDE8B,NCOA1,NUMB,TMEM108,BARD1,KSR1,JAZF1,C5,CACNA2D1,KALRN,VXN,RUNX1T1,MTMR7,SYNGR3,CD38,ZMYM4,LRRFIP1,MAGI1,TIGD7,CCPG1,COPB2,FOXN3,CNOT8,RAB28,PLAA,NGEF,C4orf33,MAP4K4,CNR1,AKAP6,LETMD1,AKAP5,SLC4A8,ABI3BP,RCHY1,MYRIP,ANKRD44,MROH8,VCAN,PDE4DIP,GREB1,RUBCN,CYBB,HDAC9,GPRASP1,ZFYVE16,LIN54,MAML1,IP6K1,DBI,GIT2,YTHDC1,ZBTB24,GSDME,DDX46,SACS,WDR20,USP3,SLC12A6,CASP8AP2,ARRDC4,ECM2,GOLT1B,AASDH,EDIL3,ANKRD46,OPTN,KMT5B,CALCRL,PAN3,DCTN4,EIF1,GPHN,EYA1,ARMCX1,TAOK3,CEP78,FCGR3A,FCGRT,FDFT1,GORAB,SLC9B2,POLK,HPCAL4,ATP2C1,ERGIC3,AP4B1,GABRG1,C15orf41,DISC1,KIAA1841,IGSF5,GCNT2,SULT1C4,PCDH17,GGTA1P,GHR,HPGDS,TNRC6A,MSL3,ADGRA3,PRUNE2,TDRKH,PCLO,FAM19A2,IRAK3,ZHX1,NCKAP1L,BACH2,HNF4G,NEGR1,SMAP1,MSL1,SCIN,FAM69A,KCND2,LAMP2,PAXBP1,HECTD2,NCOA7,LYPLAL1,MBNL1,EFHB,MEIS2,MIA2,PPM1L,POC1B,AFDN,MMP16,ADAM22,MSR1,MYO9A,NACA,NEK1,NF1,NPY,NOVA1,NTRK2,SETD4,GPR137C,CNTN3,PCDH9,PDE1C,SLC10A4,XRN1,MTRF1L,PURG,ING3,RANBP3L,PRKACB,GDPD1,WBP1L,ZSCAN32,ZIK1,PTPRD,C1orf109,SLC25A48,USP47,RAP1GDS1,ZCWPW1,OXR1,ZMAT4,RET,GTDC1,RGS3,RGS4,PBRM1,ZNF532,SETD5,CARF,GSTCD,RORB,NEK11,BAALC,ATAT1,AP1AR,CSRNP3,ATXN2,FNIP1,TNFRSF19,CASC3,SH3BGR,ASAP3,CPEB3,HKDC1,AMBRA1,CHD9,CCDC88A,ELMO2,ATF7IP,INAVA,SNRPN,USP33,PDZD2,SP4,HECW1,KDM4C,ZC3H13,CLASP2,ITPRID2,SSTR2,ST5,KANK1,JMJD6,SYNE2,SYT1,C12orf76,TCEA1,TCF12,CLASP1,SYNE1,PCDHB10,GPRIN3,FRYL,C18orf54,ITGB3BP,SLC44A1,ARL10,TIAM1,HEY1,ASXL3,C9orf85,ZNF346,RUNDC3B,AMACR,TSC1,UGT8,PLEKHH2,XRCC4,PCDH20,KCNT2,TRIM9,ZNF540,FSTL5,SLC30A4,EMSY,DNALI1,PRDM10,RNF103,ADAMTS9,HPS4,GAL3ST3,FAM47E,WNK3,FAM13C,DOCK8,RTN4,UBE3B,CASC15,NLRP3,RNF170,KLHDC1,FRMD6" MicroRNA hsa-miR-885-5p:mirSVR_lowEffct hsa-miR-885-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-103 7.68E-100 2.76E-102 2.54E-101 267 1529 "ACADM,ABHD6,FMNL2,KLHL32,ADD1,ADD2,PWWP2A,KCTD16,OSBPL6,HFM1,SPOP,ALCAM,UNC79,ALK,AMPD2,ZFAT,LRCH2,ANK2,LCORL,PHF12,PKP4,APBB2,USP37,PPP4R4,ZFYVE28,NUMB,ATP1A1,SLC4A4,ARHGEF7,GPC2,KALRN,VXN,ISPD,RUNX1T1,PRC1,CBR1,MTMR7,LRBA,DLGAP2,DLGAP1,TIGD7,CCPG1,SRSF11,SOCS6,CNOT8,EPS15L1,SULT4A1,ARMC8,COL4A5,AKAP5,AHCTF1,MYRIP,SLC35F1,RBM39,RNF14,PDE4DIP,PHF14,PUM1,RUBCN,DOCK4,ZFYVE16,CENPL,EARS2,MATR3,DAPK1,BRINP1,B3GAT3,DDX46,RPS6KL1,NR1D2,CASP8AP2,DPP6,RCAN1,DNAJB6,ABCC5,EDN1,SEMA3D,MRO,EGR3,AASS,TENM1,C3orf18,EIF1,GPHN,RACK1,KAT8,GORAB,SEC24B,SLC9B2,FER,GTF2IRD2,POLR1B,FGF14,FGFR1,TMEM164,PRKAG2,FHL1,SUCO,SEC23B,SYNCRIP,ANKFY1,C2orf88,ZNF605,NSG1,DLL3,TVP23A,MEGF11,MEGF10,GALNT15,GAD1,GALC,IQGAP2,SIGLEC8,KIAA1841,GATM,SULT1C4,ARFIP1,GGT7,TCERG1,HTATSF1,DCLK2,GNAO1,WDFY3-AS2,STMN2,BTN2A1,ZHX1,ARHGAP36,MIER3,HNMT,IDH3A,IDH3B,FAM69A,SLC35G1,METTL21A,CREG2,CYP27C1,STMN1,ZFYVE27,MARK3,MAT2A,MBP,MEIS1,MIA2,MMP16,ADAM22,MXI1,MYT1,ZC3H12B,CCDC13,NELL2,NOVA1,OPA1,PCDH8,PDE4B,DUSP26,TMIE,SNX10,STRN3,PPM1B,KANSL1,RANBP3L,SAMD9,QRICH1,CNTLN,ANKHD1,BDNF-AS,MTMR10,EML5,C1orf109,USP47,ENOX1,ZNF493,RBBP6,RADX,MSANTD2,REV3L,CCDC82,EXD2,ROBO1,YY1AP1,ELP2,CCDC102B,RPL15,ARMH4,KIAA0895L,MCMBP,ATP8B4,RTN1,SEMA6D,TRA2B,SCAF8,SGK1,ARX,FNDC3A,NLGN1,ABLIM3,WDR47,SLC6A11,ZNF334,GKAP1,COA1,RCOR3,TTC17,ANKRD36,CABCOCO1,TMCC1,PDZRN3,USP33,NMNAT2,KDM4C,ZC3H13,TSPYL2,ATP10B,ITPRID2,ZC4H2,SS18,ZSCAN29,NEK4,CEP68,VPS13A,NUDT10,PJA1,DNMBP,ADGRL3,FBXW11,TCF4,RPGRIP1L,DOCK9,PCDHB9,PUM2,TEK,ZFPM2,ITGB3BP,AP4E1,AKTIP,NR2E1,BEX4,TPM1,NPL,SYNPO2,STXBP4,DCBLD1,TSN,TTTY15,PRR18,ZNF709,VLDLR,WIPF1,RICTOR,ZIC2,ZNF711,AGMO,MKRN3,LYPD6,CELF4,ZBTB38,DPYSL5,SMARCAD1,RNF103,MPPE1,FAM13C,DOCK8,SMIM8,FBXO36,ACTR3B,MSRB3,AP3B2" MicroRNA hsa-miR-24:mirSVR_lowEffct hsa-miR-24:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-103 8.51E-100 3.05E-102 2.81E-101 306 2000 "RALGAPA1,ACHE,TMEM132B,ADD2,ADORA1,LRFN2,BEND6,OSBPL1A,TXNDC16,SRPX,CEP126,ARHGAP20,FAM135A,SYT13,DPP10,SEMA7A,FGD2,PPFIA4,APBB2,SHROOM2,SEMA4G,ARHGDIG,MARK4,NCOA1,RASL11B,STX16,RIPK1,TTLL9,ADAM15,BCL7A,NRP2,KSR1,BMPR1B,BTK,CASTOR3,RAB29,WASF1,MYRF,DDR1,LURAP1,CABP7,KALRN,PTBP2,CAMK2G,CAPN3,CH25H,HIP1R,PRC1,ZNF501,CBS,P2RX6,CD86,CBFA2T2,SCARB1,ENTPD6,C1orf52,DGKI,ZBED1,LARGE1,CRLF1,SRSF11,B4GALT6,CNOT8,TAOK2,LHX2,CLCN3,TPP1,CLTC,FBXO7,CNTFR,WHRN,COL9A1,COL11A2,MAGED1,SMARCAL1,AKAP12,HINFP,RGS6,GALNT9,CTH,GPSM1,DCAF4,RUBCN,ARHGAP32,RASSF2,DAPK1,GIT2,C2CD2L,ZC3H11A,DDX46,GUCD1,SV2B,SPOCK3,EXOG,GRIN3A,SLC29A4,CDON,DMTF1,SLC12A6,PDCD6IP,APH1A,MRO,RASA4,COPS4,TNK2,C3orf18,EIF1,MFSD10,ENPP6,NCALD,SPEG,MRPL37,ETV1,VPS26C,ANKMY1,EZH1,FCGRT,ZSCAN30,PPP1R1B,ZNF589,AMOTL2,POLK,MEX3B,IP6K2,AGAP3,SLC37A3,RASL10A,ABLIM2,HRASLS5,GALNT15,GAD1,B4GALNT1,TMEM8B,DISC1,CYP46A1,GGT5,LYVE1,BRD8,TCERG1,SPIN1,GPD2,FUT10,MCHR1,TMEM121B,GRIA2,DIDO1,GRM8,BTN2A1,RNF165,GSTM5,BVES,ADAMTS6,GABARAPL2,HMGCL,DHX35,LRRC75A,IDH3A,C2orf72,KNDC1,IL12A,FAM69A,KCNN2,KIFC3,A1BG-AS1,STMN1,PIK3AP1,ZFYVE27,MAP2,MAP4,CHIC1,MEIS1,SCAMP5,PPM1L,AFDN,MMP16,MN1,GIT1,DBNL,N6AMT1,MYO9A,P2RY13,NBL1,NFE2L2,NPTX1,SLC11A2,PCDH9,CDK18,PFKFB3,TMIE,FAM218A,SEPT4,MBOAT7,FA2H,POU6F1,LRRN3,EPDR1,MAPK7,BCAS3,WBP1L,ZSCAN32,PTPRB,CASTOR1,NKAIN1,STRC,TMEM255A,NWD1,RASGRF1,ZMAT4,TRIM68,RGS3,ZNF532,SETD5,EXD2,ELP2,ARMH4,BAALC,ABCA11P,ST6GALNAC6,KCNIP1,ATXN2,TNFRSF19,GALNT10,FOXRED1,MRAS,FERMT1,CPEB3,MYO18A,AMBRA1,FBXO11,ST6GAL1,NUBPL,LIMS2,KANSL3,ELMO2,ARFGAP1,EPC1,ZKSCAN3,ZNF667,SMARCD3,INAVA,MAPKBP1,ZSWIM8,MYCBP2,DBNDD2,CDK19,TSPYL2,DDN,NFASC,CLSTN2,SSTR1,SSPO,SEPT3,JMJD6,SLC37A2,TACR1,MLST8,FBXW11,SMG6,DMXL2,SZT2,NAT16,PCDHB3,NSD1,TNS2,CYB561A3,RNF216P1,FAM200B,SLC44A1,ENHO,MTMR14,TMEM9,HEY1,KAT6B,PIK3R5,RASD2,CDK20,NPL,CLEC2L,PLEKHH2,PLPPR2,WIPF1,KLC2,ZIC1,TRIM9,ATP6V0E2,NDRG4,POLR3H,EML6,UPF3A,DHX33,EMSY,NT5M,LINC02210,STOX2,RNF103,ADAMTS9,HPS4,ITM2C,DOCK8,UBE3B,KAT6A,CASC15,ADAMTSL3,TRAM2-AS1,TIGD6,RNF170" MicroRNA hsa-miR-1246:mirSVR_lowEffct hsa-miR-1246:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-103 9.03E-100 3.23E-102 2.97E-101 275 1623 "NCKAP5,TMEM132B,TMCC3,DPY19L2P4,PCDH19,OSBPL6,WDR35,CC2D2A,ZNF578,SPARCL1,SMIM17,UNC79,LRFN1,DPP10,PARG,PHYHD1,USP37,ARNTL,PDE8B,MARCH3,MARK4,SLC4A4,STX16,ADAM23,BACH1,BBS2,BMP7,SYNJ2,MTMR2,IL33,KALRN,SLC25A14,SEPT7,CHN1,MAP4K4,ARHGEF6,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,FAM171B,HAPLN1,MROH8,SNCAIP,RGS6,LRIG1,LRRC3B,VCAN,PPP1R16B,PHF14,PLCXD3,RIMS2,DCAF4,USP6NL,SEC14L5,GAPVD1,ARHGAP24,DCAF8,ZFYVE16,EARS2,ZNF337,KIAA0586,SPOCK2,GIT2,DNAL1,YTHDC1,ZNF804A,KLHL3,ZC3H11A,SV2B,WDR20,CPEB2,CASP8AP2,DTNA,DNM1L,GOLT1B,WDPCP,EDN1,HIPK3,KLHL5,EGR3,EIF4G2,RGS17,ELN,DENND4A,NCALD,IGSF6,EYA1,F5,CEP78,STRADA,GORAB,FECH,SLC9B2,FER,FGF13,SEMA4D,SLC37A3,FLYWCH1,FOLH1,SMC2,TRIM16,CAMKK2,ATP2C1,KHDRBS3,CELF1,OGA,GALNT15,GABRB3,IQGAP2,ERAP1,DISC1,KIAA1841,IGSF5,MSTN,ADAM28,GFRA2,TOX3,ZNF638,GNAO1,CCDC184,GPR37,DIDO1,ZNF496,GSN,MUM1,IRAK3,RASSF8,FRMD5,GABARAPL2,AGFG1,IRF8,C2orf72,ZIC5,METTL21A,IPO5,LIG4,LIMS1,PIK3AP1,MAN2A2,CHIC1,TM6SF1,SRSF12,MEST,MIA2,KITLG,MID1,MMP16,MXI1,LAYN,BEX5,ZC3H12B,NPTX1,NUCB2,TBC1D25,OCRL,P2RY1,GPR137C,CNTN3,PCSK5,PDE4D,PFKFB3,NLGN3,CCSER2,PLCL1,PURG,PMP22,STRN3,LRP12,NECAB2,ING3,FSD1,POU6F1,PPARA,PPM1B,TATDN3,PPP2R5E,PRKACB,PKIA,HYDIN,DCHS2,SNRK,TMEM260,PTPRD,TMEM255A,USP47,FAM66C,PRRT2,SLC25A36,PBRM1,RNASEL,CCDC82,SETD5,NEK11,TCP11L1,RPS6KA2,LRRK2,ATAT1,NCBP3,SEMA6D,SCP2,ZFP2,TRA2B,SCAF8,SH3GL3,KIF16B,HKDC1,CHD9,FHOD3,KANSL3,ATF7IP,GKAP1,MAST1,ANKRD36,SNAP25,MBD5,SNRPN,MYO16,PDZD2,TRERF1,BDP1,SP2,UHRF1BP1L,UNC5B,PEG10,ZNF423,NFASC,LARP4,ADHFE1,KLHL7,SYNE2,VPS13A,SYN1,TACC1,PJA1,TCEA1,TCF4,SATB2,RPGRIP1L,DOCK9,PCDHB9,SIK3,ZFPM2,FAM124A,RIMBP2,WBP2,SYNPO2,STXBP4,TRPS1,MGAT5B,WIPF1,RICTOR,XRCC4,ZIC2,ZNF708,ZNF28,ZSCAN26,ANKS1B,SLC30A4,EMSY,CADM2,TRIM16L,WNK3,PARP11,EPM2A,RGS7BP,FZD3,DOCK8,ACTR3B,ADAMTSL3,NETO1,SOCS4,CPNE4,SPATA13" MicroRNA hsa-miR-124*:mirSVR_lowEffct hsa-miR-124*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.91E-103 1.07E-99 3.81E-102 3.51E-101 283 1719 "ASIC1,KLHL32,GALNT13,PLEKHH1,AP2A2,OSBPL8,SMIM17,ALCAM,BBOX1,AMPH,CDC42BPA,LRCH2,BCAS1,TNRC6C,TMEFF1,ARNTL,PDE8B,MARCH3,CCAR2,ATP1A1,ATP1B3,RNF182,N4BP2L1,BMP7,MTMR2,LDLRAD4,CACNB4,CAMK2A,CAMK2B,VXN,SPAG9,ARHGEF2,MAGI1,CCPG1,CACNA2D2,NDST3,QKI,CNGA3,AKAP7,ARMC8,LETMD1,ABI3BP,GAL3ST1,BAG4,MYRIP,ZNF385A,CDC42BPB,C2CD2,CRMP1,RNF14,ANKRD44,CSF1,LRRC3B,CSNK1G3,DZIP3,GREB1,CYBB,KIAA0408,KATNAL2,MATR3,GIT2,ARMCX2,YTHDC1,HEPH,GSDME,SNAP91,SPOCK3,RAB39B,DMD,DNM1,PDCD6IP,DTNB,DNAJB6,ABCC5,E2F5,WDPCP,EDN3,HIPK3,RASGRP1,YAF2,FAM13A,PHF20L1,EGFR,MBNL2,RASA4,STARD3NL,USPL1,COQ7,EPHB1,STX2,SRRM1,IGSF6,PIPOX,ANKMY1,RASL12,EYA1,F5,SH3YL1,ACSL4,DLC1,FCGR1A,CEP78,CHST15,FECH,SEC24B,FER,PRKAG2,POLK,MEX3B,AGAP3,WDR83,NBEA,POMT1,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,ST6GALNAC3,CSPG5,FAM120B,B4GALNT1,ERAP1,ZNF559,DISC1,SULT1C4,WASHC2A,AHDC1,ADAM28,PPARGC1A,TCERG1,SPIN1,GLI2,GLYR1,TNRC6A,GNAL,FUT10,ATP2B1-AS1,GRIA2,ADAMTS13,SOX21,MAP4K5,UBE2QL1,ZHX1,HMGCR,ZDHHC15,NEGR1,LRRC75A,TJAP1,ZNF678,INSM1,METTL21A,KCNN3,KHK,KIT,STXBP5,KTN1,LAMP2,SYTL4,NCOA7,LSS,MATN2,TM6SF1,MEIS1,MEIS2,KCTD6,POC1B,AFF1,XRRA1,MYO9A,VWA2,SLC11A2,TREM2,PDE4D,GNG2,CYTL1,TMIE,KCTD15,NLE1,JAKMIP1,MTRF1L,PLXNB1,PRIMPOL,PPP1R1A,PRKCB,MAPK4,MAPK9,DCHS2,BCAS3,VPS13C,PIGG,CNTLN,PTCH1,ANKHD1,NKAIN1,TTC13,TUG1,PPP2R3C,PRRT2,RGS12,RIC8B,RNASEL,ZFHX4,C12orf49,ALG9,CYB561D1,ROBO1,ROBO2,BAALC,SPIN3,GLDN,HUNK,ZNF568,GALNT10,SCAF8,SH3GL3,FBXO11,CNKSR2,NUBPL,PPP4R3A,KANSL3,NAPB,ATF7IP,SLC22A4,DMRTC1,MBD5,SNRPN,MYO16,DOP1A,BDP1,TSNAXIP1,SP4,UHRF1BP1L,MYCBP2,TSPYL2,SAMSN1,SSTR1,TTBK2,DIP2A,KANK1,SEPT3,SYT1,TBCEL,FBXW11,KLHL4,SATB2,SZT2,SYNE1,PCDHB6,SIK3,FAM200B,C18orf54,AKTIP,RIMBP2,R3HDM1,CSMD1,PIK3R5,TPM1,NPL,C9orf85,RUSC1,ZKSCAN5,FAM155A,UBE3A,LINC00689,BCL2L13,XPO1,XRCC4,AGMO,ZNF138,ZNF177,EML6,SMARCAD1,DNALI1,STOX2,RNF103,GAL3ST3,DOCK8,UBE3B,CASC15,TRAM2-AS1,FRMD6,RNF146" MicroRNA hsa-miR-145:mirSVR_highEffct hsa-miR-145:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.18E-103 1.22E-99 4.33E-102 3.98E-101 255 1396 "RALGAPA1,CLK4,NCKAP5,FMNL2,CCDC85A,TMCC3,PTCHD1,SLC24A4,MTUS1,HECW2,RTL9,OSBPL1A,SEMA6A,SPOP,FAM135A,AMPD3,LCORL,PKP4,APAF1,EPB41L5,UPRT,LGR5,SEMA4G,PPP4R4,ARNTL,ZBTB10,BARD1,NRP2,CFLAR,DST,SYNJ1,C5,IL33,THSD7A,CAST,MTMR7,CDH2,MAGI1,CFL2,LHX2,FAM189A2,CNN3,SLC4A8,TBPL1,BAG4,ZFP28,ZNF385A,CPS1,CRHBP,HAPLN1,ANKRD44,SIPA1L1,VAC14-AS1,PDE4DIP,PLXNA4,APPL1,UBXN2A,PHF14,KATNAL2,RIPOR2,ARHGAP24,KCTD8,TMEM170A,BRINP1,ARMCX4,YTHDC1,ZC3H11A,DDX46,WDR20,EXOG,NR1D2,PDCD6IP,RCAN1,ARRDC4,DTNA,EBF1,FCF1,PHF20L1,EGFR,KMT5B,C3orf18,DCTN4,GPHN,VPS26C,ADGRV1,FAM198B,ACSL4,ZNF589,GORAB,GTF2IRD2,SPSB4,FGF14,FGFR3,RGPD5,FLT1,TMEM107,UFM1,ST6GALNAC3,MEGF10,HRASLS5,DISC1,LRRC37A6P,IGSF5,MSTN,WASHC2A,ADAM28,GGTA1P,GGT7,LYVE1,STARD3,KDM2B,HTATSF1,LUZP2,KCNMB4,GPD2,PRUNE2,ATP2B1-AS1,GRB10,FAM19A2,PSIP1,MIER3,GABARAPL2,ZDHHC15,ZNF181,ZNF546,SCIN,ZNF678,SLC35G1,METTL21A,CYP27C1,LAMP2,HECTD2,NCOA7,MARK1,MAT2A,MEIS1,SRSF12,MEST,MID1,PPM1L,MMP16,COMMD5,N6AMT1,CNOT4,NRCAM,SMIM11A,GPR137C,FAM218A,SNX10,XRN1,FAM216A,JAKMIP1,PDZRN4,PSAT1,EXOSC10,RETREG2,PPARA,TATDN3,PPP3CA,MAPK4,MAPK9,PRPSAP2,BDNF-AS,TMEM260,EML5,ZSCAN2,TTC13,ZNF615,TMEM255A,SH3TC2,RADX,TRIM68,REV3L,UBR7,SLC25A36,ZFHX4,GSTCD,RPE,NEK11,ATP8B4,PTGR2,RPS20,CLIP1,NCBP3,ZNF331,AP1AR,ATXN2,ZFP2,COPZ1,KIF21A,FNDC3A,R3HDM2,NLGN1,FAM81A,CPEB4,TTC17,SNAP25,FAM126B,USP33,ZNF423,CLASP2,CLSTN2,POGZ,ZNF302,ZC4H2,SS18,ERBIN,ELOVL4,RGL1,PRRC2C,SYT1,ANKRD28,C12orf76,MTCL1,MCF2L,TAF9,DMXL2,SATB2,SYNE1,DOCK9,SLC19A3,OBSL1,FAM200B,ZNF106,ENHO,MTMR14,HEY1,TLR4,CSMD1,TP53BP1,TPM1,C9orf85,SMUG1,PPIL6,RPL7L1,UGT8,PLEKHH2,USP1,TBC1D15,WIPF1,CFAP298,PCDH20,ZNF711,ZNF708,KCNT2,ZNF138,UPF3A,RNF103,TMEM178A,NAV3,FIP1L1,UBE3B,CASC15,RNF170,NETO1" MicroRNA hsa-miR-1293:mirSVR_lowEffct hsa-miR-1293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.61E-103 2.02E-99 7.13E-102 6.56E-101 255 1399 "KDM5D,KLHL32,PLEKHH1,ADRA1D,OSBPL1A,SORCS2,CC2D2A,SPOP,LTBP4,ALK,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,PPFIA3,SEMA4G,SPTBN4,PLA2G4C,NCOA1,NUMB,BBS2,GYG2,DDR1,CALB2,KALRN,METTL6,SEPT7,LOC730101,LARGE1,NOG,NUMBL,CHN2,NDST3,EPS15L1,TPP1,IGLON5,IQCK,COL11A2,SLC4A8,SLC35F1,CDC42BPB,C2CD2,RBM39,CRY2,ANKRD44,GDA,CSF1,RGS6,LRRC3B,CSNK1E,RASGEF1C,SLITRK5,ZSCAN23,GAPVD1,SNPH,TM9SF4,MFAP3L,TMEM130,GUCD1,RHOBTB1,TMCC2,SEC16A,DLX1,DMD,DMPK,USP3,CD99L2,SLC29A4,DPYSL2,EBF1,ANKRD46,TMTC1,CELSR3,PHF20L1,EGFR,EIF4G1,TNK2,ELN,C3orf18,ZNF549,SPEG,VPS26C,SIRPB1,MRVI1,HSPA12B,ABCA8,ZNF461,TAOK3,ZMYND10,FKTN,ZNF589,GORAB,SLC9B2,POLK,SUCO,FOXF2,AGAP2,SYNCRIP,EVL,COQ5,ZBED3,SPECC1,CELF1,B4GALNT1,SRCAP,GPR162,GGT7,GHR,PPARGC1A,BRD8,CRCP,MSL3,KDM2B,DCLK2,GNAO1,GP1BB,GPD1,TMEM121B,SPACA9,RNF165,FAM222A,NXPH3,MAN1B1,ATXN2L,SYNPO,AGBL5,HNF4G,HSPA1L,SMAP1,MYLK2,LRRTM1,ITGAM,L1CAM,PAXBP1,MAT2A,MBD1,PPM1L,COL28A1,BLOC1S2,PTOV1,N6AMT1,MYO7A,NCAM2,NFE2L2,NPY,NTRK2,NUCB2,OCRL,OXTR,ZNF655,FAM218A,SLC25A23,ZNF426,MTRF1L,PNMA3,MAPKAP1,SCHIP1,POLR2F,KANSL1,VSTM2L,PKIA,MAPK3,KLK6,PSD,BCAS3,VPS13C,QRICH1,NCR3LG1,PTPRN,NKAIN1,CCDC40,ZDHHC14,MSANTD2,TRIM68,PRRT2,RGS12,ALG9,NEK11,TCP11L1,NCBP3,RMI1,SCN2B,SCN7A,SCN8A,GALNT10,SGK1,KIF16B,BTBD3,FAM214B,SLC8A1,SLC11A1,ELMO2,INAVA,MAPKBP1,MBD5,DOP1A,SP4,SPTB,IQSEC2,NFASC,CLASP2,ITPRID2,NKAIN2,DIP2A,ADHFE1,PHLDB1,NSFL1C,ADAMTS17,ARC,SYT5,CUX2,TRIM2,CLASP1,SZT2,SYNE1,PCDHB9,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,SLC44A1,MTMR14,TK2,ERCC6L2,RIMBP2,CABIN1,TPM2,RGMB,PDSS1,DCBLD1,TSC1,TTTY15,UBTF,PLPPR2,CCDC136,VLDLR,CLDND1,ZBTB14,LYPD6,POLR3H,AMZ1,EML6,ZNF213,MFF,LINC02210,STOX2,FIP1L1,FAM47E,ST7,TTC7A" MicroRNA hsa-miR-106b:mirSVR_highEffct hsa-miR-106b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.49E-103 2.51E-99 8.84E-102 8.14E-101 266 1525 "KCNH8,NCKAP5,SLC24A4,HACE1,C1QTNF3,ABCD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,TNRC6C,LINC00173,STK33,RASL11B,SLC4A4,ATP1B3,DPY19L3,ADGRB3,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,THSD7A,USP6,C1orf52,TIGD7,CFL2,TAOK2,EPS15L1,ABCG2,SULT4A1,ARMC8,COL4A5,AKAP5,AHCTF1,CNRIP1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,ARHGEF10,PDE4DIP,UBXN2A,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,DNAL1,MYEF2,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,FAM78B,DNAJB6,DNM1L,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,PLEKHA1,CERCAM,MRNIP,DNAJC27,KATNAL1,EZH1,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,SPECC1,UFM1,PDLIM5,ST6GALNAC3,GABBR1,TRAF3IP2,B4GALNT1,ERAP1,SYT17,DISC1,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,CIT,AP4S1,IRAK3,HAS2,MSL1,METTL21A,KCNN2,KIF5A,SFXN5,SYTL4,HECTD2,SMAD1,MAN2A2,MAP6,AQP11,LRP1B,SRSF12,MID1,POC1B,XRRA1,MSR1,MXI1,MYCN,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,ETFRF1,PDE4D,PDE1B,ZDHHC8,CCSER2,JAKMIP1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PRKACB,PKIA,HYDIN,PSD,VPS13C,PIGG,PTPN13,PTPRD,PTPRO,CEP97,USP47,FAT4,OXR1,RASGRF2,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,CARF,ZNF671,MCMBP,ST6GALNAC6,SALL1,CSRNP3,LRFN5,SH3GL3,CHD9,FNDC3A,SYBU,WDR37,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,RBM34,USP33,IQSEC2,ZBTB43,SPART,LMO3,ATP10B,ITPRID2,ERBIN,RGL1,ADHFE1,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,PLEKHH2,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,MAP3K12,EMSY,CADM2,SLC38A1,PRDM10,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-647:mirSVR_lowEffct hsa-miR-647:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.58E-103 2.56E-99 8.99E-102 8.28E-101 282 1713 "EMILIN3,GALNT16,PSMG3-AS1,ADCY6,PTCHD1,FAHD2CP,MTA3,SLC24A4,AP2A2,HACE1,SPOP,FAM135A,AMPD3,DPP10,EP400,PKP4,TNRC6C,SPTBN4,ZSCAN18,NUMB,DYNLL1,STX16,ZNF582,ADGRB1,JAZF1,AP1M1,CA8,CACNA1B,HAP1,PTBP2,CAST,HIP1R,ENTPD6,ARHGEF2,LRRFIP1,MAGI1,UBE2L6,NUMBL,CFL2,ARHGAP22,NRXN3,NGEF,ABCG2,QKI,MAP4K4,CNN3,AKAP6,SLC4A8,SMARCAL1,SLC35F1,CDC42BPB,SH2B1,SNCAIP,RGS6,SEC24C,VCAN,PDE4DIP,PLXNA4,ZSCAN23,ARHGAP32,KATNAL2,HDAC4,ZFYVE16,TMEM170A,IP6K1,GIT2,MFAP3L,RUSC2,LYPD1,POM121,SV2B,SPOCK3,SGSM2,WDR20,EXOG,DMD,DPYSL2,ACOT8,GOLT1B,E2F6,EDNRA,PHC2,EGR3,AASS,EIF4G2,STARD3NL,HSD17B14,EPB41L2,ZNF549,DNAJC27,CLVS1,TMEM132C,PTK2B,DLC1,STRADA,ZNF589,FER,SPSB4,POLK,IP6K2,EVL,SPECC1,PDLIM5,CELF1,GABRA3,GALC,ZNF274,DISC1,TUBGCP4,SULT1C4,ADAM28,GHR,PPARGC1A,ZNF276,CRCP,GLI2,WDFY3-AS2,PCLO,GRB10,ADAMTS13,CIT,BTN2A1,RNF165,SOX21,PSIP1,FAM107A,RNFT2,ATOH8,PADI2,FRMD5,DDX19B,GABARAPL2,HNF4G,HNMT,TCEAL6,DHX35,CELF5,MYLK2,ZNF546,KNDC1,NME9,CDH20,CREG2,KIF2A,L1CAM,STMN1,SYTL4,PIK3AP1,ZFYVE27,MARK3,MBD1,TM6SF1,MEIS2,AFDN,MYO9A,RTL5,P2RY13,NEFH,NFIX,VWA2,DNHD1,NPR2,SLC11A2,TBC1D25,OGG1,CDK18,GNG2,NALCN,ZNF655,XRN1,PRIMPOL,PNMA3,ANKRD16,SCHIP1,SDK2,KANSL1,CEP41,PRODH,MASP1,WBP1L,ANKHD1,PTK2,PTPRO,ZSCAN2,NKAIN1,SH3TC2,ZCWPW1,GAL3ST4,RFX2,KCTD17,PBRM1,ALG9,ELP2,ZNF671,STX1B,TRAPPC13,FAM192A,SEMA6D,SCN2B,FOXRED1,SH3GL3,CHD9,DZIP1,SLA,KANSL3,ARHGEF40,SLC14A1,ARFGAP1,CDK5RAP2,KIF13A,CABCOCO1,SNRPN,PDZRN3,KDM4B,DOP1A,TSNAXIP1,DOK5,ZSWIM8,KDM4C,SPTB,POGZ,NKAIN2,DIP2A,PHLDB1,SEPT3,PRRC2C,RHBDL3,ARHGEF9,ADAMTS17,SYN2,MTCL1,CAMTA1,TAF6,TBCEL,TPCN2,RPGRIP1L,SYNE1,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,GPR161,SLC44A1,TMEM9,ERCC6L2,LRRC8A,RIMBP2,KAT6B,NPL,SYNPO2,ELP5,TRPS1,PPIL6,TTTY15,UBE2H,SLC35A4,LMF1,XRCC4,LGI4,ZNF24,CELF4,TMEM198,ANKS1B,NT5M,RNF103,SEMA3B,URM1,PPP1R3F,PCBP4,DNAH10,RSPRY1,NHSL1,NETO2,RNF146,AP3B2,SOCS4,PRRT4" MicroRNA hsa-miR-9*:mirSVR_highEffct hsa-miR-9*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.75E-103 3.21E-99 1.12E-101 1.04E-100 277 1655 "CLK4,NCKAP5,KLHL32,PWWP2A,PTCHD1,ADRA1D,ADRB2,MTUS1,OSBPL1A,OSBPL8,AMPD3,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APBA2,USP37,CDK13,CCDC74A,ZBTB10,SLC4A4,TTLL9,ADGRB3,BID,MTMR2,JAZF1,SGCE,WASF1,CA8,KALRN,SLC25A14,CAST,CBLN1,LDB2,KRIT1,USP2,C1orf52,L3MBTL4,MAGI1,CFL2,CLCN3,IQCK,ABCG1,CSNK1E,OSBPL3,CSNK1G3,APPL1,PHF14,PNPLA8,PUM1,CYBB,HDAC9,GPRASP1,ZFYVE16,ZNF337,KIAA0586,KCTD8,DAPK1,ARMCX2,ZC3H11A,RHOBTB1,RAB39B,DMD,CPEB2,RCAN1,DTNA,DNAJB6,ABCC5,DNM1L,E2F5,SNX29,ANKRD46,HIPK3,FSD1L,YAF2,PHF20L1,APH1A,EGFR,EGR3,PAN3,VPS13B,SRRM1,ABCA8,PTK2B,RACK1,CEP78,FCGR3A,GORAB,FER,POLR1B,SPSB4,FGF14,PRKAG2,FHL1,POLK,MEX3B,NELFCD,JKAMP,PDLIM5,CAMKK2,STAU2,MSANTD4,CHL1,C15orf41,ACSS1,LRRC37A6P,CPLX1,ARFIP1,SESN1,ADAM28,MMADHC,GHR,COPS8,GNAL,GRIA2,BVES,FAM107A,GUCY1B1,ZHX1,ACOT7,HNF4G,ZDHHC15,HSF2,IFI16,ZNF181,SOWAHA,RBPJ,ZNF678,INSM1,LRRTM1,KCNN2,IPO5,LAMP2,NCOA7,PIK3AP1,MAP4,MARK1,KITLG,MITF,MN1,ZNF680,MXI1,MYO9A,NEXMIF,NDP,SLC11A2,P2RY1,PCSK1,PDPK1,PFKFB2,OLA1,NALCN,ZNF655,ZFYVE21,RETREG1,PLIN1,STRN3,LRP12,EPB41L4B,SH3KBP1,MINDY2,CEP41,MAPK4,MAPK9,SAMD9,CNTLN,TMEM260,PTPN13,PTPRB,PTPRG,PTX3,PEX2,ZNF615,PID1,TMEM255A,RBBP6,RADX,KHDRBS2,RDX,MORC4,FIGN,SLC25A36,ZFHX4,CCDC82,CARF,GSTCD,MRAP2,ADAL,RPS6KA2,LRRK2,CLIP1,RTN1,RYR3,ATXN2,SCN7A,ZFP2,HSPA4L,CPEB3,FHOD3,SLC12A2,BTBD7,CMTR2,SNRPN,SP4,ZC3H13,MCF2L2,LMO3,CLASP2,POGZ,ITPRID2,LARP4,NXT2,CEP68,PHLDB1,SEPT3,SYNE2,SYT1,SLC37A2,PJA1,TBCEL,TCEA1,TRIM2,TCF12,SYNE1,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,C18orf54,ITGB3BP,AKTIP,TIAM1,HEY1,TK2,ASXL3,NR2E1,TRIO,TRPS1,ZKSCAN5,TUBB1,FAM155A,UBE2H,UGT8,FLRT2,PLEKHH2,TBC1D15,WIPF1,GUSBP1,ZFP37,ZNF19,ZNF24,LYPD6,ZNF184,EMSY,CADM2,STOX2,RNF103,NAV3,PPP1R3F,KCNAB1,FAM47E,PARP11,PHTF2,FBXO36,CASC15,KLHDC1,FXR1,FRMD6,NETO2,DPF3,SOCS4,FAM198A" MicroRNA hsa-miR-505*:mirSVR_lowEffct hsa-miR-505*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.14E-103 3.43E-99 1.20E-101 1.10E-100 282 1715 "VWA5B2,ASPHD1,SYN3,EMILIN3,METAP1D,GALNT16,GALNT13,ADD1,USP31,ADORA2A,CASKIN1,AK2,C1QTNF1,CARNS1,MARCH4,PCDH10,ALK,SYT13,AMPD2,LCORL,APAF1,APBA2,EPB41L5,APLP1,FAM131A,PHYHD1,PPFIA3,SEMA4G,TMEFF1,ARNTL,ARRB1,ZSCAN18,NUMB,CCAR2,DPY19L3,RIPK1,NRP2,CFLAR,KSR1,SYNJ1,SYNJ2,NAE1,CACNA1G,KALRN,PTBP2,CAMK2A,CAMK2B,RUNX1T1,ENTPD6,LOC730101,ASIC3,NRXN3,NGEF,FAM189A2,MAP4K4,IGLON5,CNTN1,AKAP7,PCYT1B,ARMC8,WHRN,ABI3BP,SMARCAL1,SEC31B,C1QL2,CS,CSF1R,RGS6,DZIP3,PITPNM3,ZSCAN23,DCAF4,MYADM,RIPOR2,TBC1D5,DBN1,ARMCX4,PITPNC1,SPATA2,ELMO1,KIAA0319,DDX46,RHOBTB1,SV2B,DNM1,HS3ST2,MED12,SLC12A6,DNAJB6,EDN1,ANKRD46,CNNM1,RASGRP1,YAF2,EIF5,SRPK3,EPHB1,SRRM1,SPEG,VPS26C,DNAJC27,SIRPB1,KATNAL1,F5,TMEM132C,CHST15,FCGR3A,STRADA,FDFT1,GTF2IRD2,FGF1,POLR1B,BAIAP2,AMOTL2,SYNCRIP,FLT1,FLYWCH1,NBEA,HVCN1,ERGIC3,STAU2,DOT1L,MEGF11,MEGF10,GABBR1,CHL1,ZNF234,ZNF274,GHDC,SRRM4,GATM,ALDH1L1,TUBGCP4,GGTA1P,PPARGC1A,RUNDC3A,TTBK1,SPIN1,RAB30,DCLK2,GNG4,ADGRA3,GPR34,SPACA9,ADAMTS13,PRDM5,LINC01089,KAT7,RNFT2,ATOH8,UBE2QL1,PADI2,HMGCL,ZDHHC15,FAM95B1,KIAA1755,TJAP1,SCIN,ITGA7,SLC35G1,KHK,KIF5A,KIT,LAMP2,STMN1,LSS,CLEC18A,MAN2A2,MAP6,MBNL1,MIA2,KITLG,SCAMP5,MID1,PPM1L,N6AMT1,TAGLN3,HNRNPM,NEK1,CNOT4,SLC11A2,OGG1,OXTR,PDE1B,PDPK1,GPR173,TMIE,CCSER2,XRN1,SLC25A23,TATDN3,PPP2R5E,PPP5C,MAPK4,MAPK10,DIRAS2,CYBC1,WDR25,ANKHD1,ELOVL2,STK32A,PTPRO,RIPOR1,SH3TC2,NWD1,RASGRF1,RASGRF2,ZDHHC14,TRIM68,PRRT2,RGS3,RGS12,MRPS18A,ALG9,ROBO1,RPL15,KIAA0895L,ATP8B4,AP1AR,ATXN7,PRCD,FOXRED1,FAM81A,SLC2A5,SLC12A4,SLC22A4,SMARCD3,TMCC1,MYO16,PDZD2,ZSWIM8,SPTAN1,IQSEC2,MCF2L2,NFASC,CAMTA2,ZC4H2,STAU1,SEPT8,CEP68,DIP2A,STAC2,STX1A,SEPT3,NSFL1C,COBL,MTCL1,TAL1,ALG1,IQCE,ATMIN,RPGRIP1L,SYNE1,HIF3A,RNF216P1,FAM200B,SIRT1,DICER1-AS1,ITGB3BP,THRA,TMEM9,ANKRD24,PRRT1,TNS1,CDK20,ZNF346,SMUG1,TUBB1,PLEKHH2,BCL2L13,VSNL1,RBFOX3,KLC2,ATP6V0E2,CRB2,SH3GLB2,ZNF213,MFF,PRTFDC1,RGS7BP,UBE3B,ST8SIA2" MicroRNA hsa-miR-1286:mirSVR_lowEffct hsa-miR-1286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.24E-103 4.05E-99 1.41E-101 1.29E-100 271 1586 "ABCF1,ACADM,ADCY6,CCDC85A,ADD1,ADD2,MTA3,ARHGAP20,PITPNM2,AMPD2,PI16,SUGT1P4-STRA6LP-CCDC180,GAS7,CASK,TMEFF1,ZFYVE28,ARHGDIA,LINC00173,CDK13,MARCH3,NUMB,ATP1A1,ATP6V0A1,ADAM15,MPDZ,BCL7A,NRP2,SYNJ2,CACNA1G,CACNA1B,CAMK2A,CH25H,CBFA2T2,LRBA,CDC25B,EPS15L1,CPNE6,STOML1,QKI,HECTD1,PICK1,CNTN1,AKAP6,SUMF2,CNRIP1,CDC42BPB,PREPL,RBM39,CSF1R,IPCEF1,SIPA1L1,PLXNA4,PITPNM3,GREB1,CYBB,MYADM,EARS2,KCTD8,IP6K1,DCTN1,JAKMIP2,B3GAT3,MFAP3L,KIAA0753,RUSC2,TMEM130,DDX46,POM121,WDR20,CD99L2,DOCK2,SLC12A6,DPH1,PDCD6IP,MAMLD1,FARSB,AASDH,ANKRD46,HIPK3,TMTC1,FSD1L,OPTN,MBNL2,ELN,C3orf18,MRPL10,ETV1,SIRPB1,CLVS1,ST3GAL6,CEP78,ZNF589,GTF2IRD2,POLR1B,FGF11,FGF13,FGFR1,PRKAG2,UBE2E3,NELFCD,PDLIM5,FAM49B,KHDRBS3,CELF1,ST6GALNAC3,SDCBP2,IP6K3,GHDC,INPP5K,LRRC37A6P,TUBGCP4,NTNG2,TTBK1,CRCP,MSL3,KDM2B,POLL,FUT10,STON1,TMEM121B,GRM2,CIT,BTN2A1,GUCY1A1,HAS2,PADI2,MAN1B1,BACH2,ACOT7,SYNPO,AGBL5,ZDHHC15,LRRC75A,GAREM2,TJAP1,NME9,ITPKB,SLC35G1,KCNH2,KCNK3,KCNN2,CREG2,CAMK2N2,NCOA7,PACRG,SMAD1,GPR155,ZFYVE27,ADAM11,CHIC1,MEF2C,KITLG,XRRA1,MMP16,MN1,PTOV1,MXI1,MYCN,NF1,NOVA1,NOVA2,OCRL,ENPP2,PFKFB3,PKM,PNMA3,TRHDE,EPB41L4B,PPP2R5E,KANSL1,CEP41,MAPK4,MAPK9,DIRAS2,MASP1,CNNM2,BCAS3,WBP1L,CNTLN,PTPRE,ZSCAN2,FAM66C,SUSD4,RASGRF1,MORC4,GTDC1,FIGN,RGS12,TMLHE,PNMA8A,ZC3H14,TCP11L1,MEG3,KCNIP3,MAPK12,SCP2,FNIP1,SEC14L1,ZNF821,FAM102A,FRMPD1,MYO18A,CHD9,NUBPL,LIMS2,CCDC88A,ELMO2,SMARCA4,IFT122,SNRPN,TMCC1,PDZRN3,DOP1A,TSNAXIP1,ZHX3,ERC1,ATP10B,ST5,SEPT8,DIP2A,JMJD6,COBL,MLST8,FAM208A,ADGRL3,AGTPBP1,TBCEL,MGRN1,TCEA1,ZEB1,TPCN2,CLASP1,SYNE1,NAT16,PUM2,USP32P1,CDH22,SLC44A1,THRA,MTMR14,TMEM9,TK2,ASXL3,KAT6B,PIK3R5,TPM2,TRO,STXBP4,TRPM2,SSBP2,TTTY15,HIRA,RPL7L1,WRN,KCNK12,TRIM9,ZFP41,ATP6V0E2,LYPD6,AMZ1,LAMP5,EMSY,SLC38A1,GDPD5,NAV3,SLC17A7,DOCK8,ADAMTSL3,RNF170,RNF146,CPNE4" MicroRNA hsa-miR-15a:mirSVR_highEffct hsa-miR-15a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.90E-103 4.42E-99 1.53E-101 1.41E-100 260 1460 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,GALNT13,AXIN2,ADRB2,AP2A1,SRPX,ARHGAP20,OGT,ANK2,BCAS1,PPFIA3,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,SLC4A4,TTLL9,MPDZ,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,CA8,CACNA1B,KALRN,PTBP2,CAST,RUNX1T1,ARHGEF1,TIGD7,CHRNA4,PPT2,CLCN3,TPP1,QKI,SLC4A8,ABI3BP,TBPL1,MYRIP,SEC31B,PREPL,CRYM,LRIG1,SOCS5,PDE4DIP,ERC2,ZSCAN23,USP6NL,ARHGAP32,GAPVD1,RIPOR2,DCAF8,KCTD8,IP6K1,GIT2,ARMCX2,YTHDC1,JAKMIP2,SPOCK3,DNM1,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,PHF20L1,MBNL2,PLEKHA1,RCAN2,DENND4A,CEP85L,SPEG,EYA1,NRN1,ACSL4,RACK1,FGFR1,SUCO,RGPD5,SLC37A3,PDLIM5,CELF1,CSPG5,NSG1,STAU2,GALNT15,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,SPIN1,TNRC6A,FERMT2,GPD2,PCLO,RNF165,RASSF8,ZHX1,FRMD3,MSL1,RBPJ,NIM1K,ZNF678,INPP1,NME9,SLC35G1,KCND2,KIF2A,KIF5A,LAMP2,SYTL4,PACRG,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MEST,MN1,MSR1,THYN1,RTL5,NDP,SLC11A2,NTRK3,GPR137C,CNTN3,ETFRF1,PCDH9,PDE3A,PDE4D,PDPK1,SLC10A4,PIK3R1,JAKMIP1,PSAT1,MAGEL2,RETREG2,EPB41L4B,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,PIGG,CNTLN,STK32A,ZSCAN32,PTPRD,EML5,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,ZDHHC14,RDX,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,ARMH4,FBXW7,ABCA11P,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN8A,COPZ1,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,SHC4,NLGN1,ANKRD6,FAM81A,ARHGEF40,KBTBD4,SLC22A4,TET1,CPEB4,RCOR3,SNAP25,MBD5,SNRPN,UNC5B,ZC3H13,TSPYL2,NFASC,PHLDB1,PRRC2C,SYNE2,VPS13A,SYPL1,C12orf76,ADGRL3,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,NR2E1,ERCC6L2,KAT6B,TP53BP2,TPM2,RUNDC3B,LGI4,TRIM9,FSTL5,EML6,ANKS1B,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,ADAMTSL3,SNX14" MicroRNA hsa-miR-1303:mirSVR_highEffct hsa-miR-1303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.11E-103 5.10E-99 1.76E-101 1.62E-100 249 1338 "CCDC85A,GALNT13,KIAA1211,DPY19L2P4,SLC24A4,WDR35,CEP126,ARHGAP20,FAM135A,ANK2,SUGT1P4-STRA6LP-CCDC180,FAM131A,TMEM108,RNF182,BACH1,RGS11,ZNF599,CACNA1G,DDR1,CALB1,THSD7A,PTBP2,CH25H,CBLN1,CBS,MTMR7,LRBA,ZBED1,LRRFIP1,L3MBTL4,MAGI1,COPB2,CHN1,PPT2,MAP4K4,LY86,CNTN1,TBPL1,CREM,ENTPD4,RNF14,CLIP3,TRIM69,CSNK1E,CSNK1G3,ERC2,PUM1,RIMS2,CENPL,DAPK1,GIT2,ARMCX4,YTHDC1,ZNF804A,MYEF2,ELMO1,SV2B,TMCC2,DMTF1,CASP8AP2,DPYSL2,ACOT8,DNM1L,GOLT1B,E2F6,EBF1,EDNRB,ANKRD46,FCF1,RASGRP1,FSD1L,PHF20L1,EBI3,EGR3,CALCRL,DCTN4,EPB41L2,SH3YL1,ZSCAN30,GORAB,GTF2IRD2,FGF1,FGF11,HPCAL4,FOXO3,SEMA4D,STAMBP,ATP2C1,DLL3,AP4B1,ZMAT1,ERAP1,DISC1,GATM,TUBGCP4,GDF9,ADAM28,GFRA2,PPARGC1A,LYVE1,ZNF276,CRCP,TCERG1,DBF4,ZNF638,GNAL,ZNF782,GPD2,FUT10,CCDC184,FAM19A2,RNF165,RNFT2,ZHX1,FRMD3,TNFAIP8L3,MIER3,SHISA6,MSL1,ZNF546,SCIN,SLC35G1,KCND2,KCNJ16,MAP2,MATN3,MBD1,MBNL1,SRSF12,XRRA1,ADAM22,MYO6,MYO9A,NDP,NOVA1,P2RX7,P2RY1,DPY19L2P2,PCDH9,PDE1C,ENPP2,FAM218A,GPSM2,FAM216A,POLR2F,TATDN3,PPP2R5E,PPP3CA,PRKACB,EPDR1,HYDIN,WBP1L,SNRK,CNTLN,PTCH1,MTMR10,PTPRG,CEP97,RAP1GDS1,KHDRBS2,MSANTD2,RDX,RGS12,RIC8B,ZFHX4,ZNF532,ARMC5,ROBO1,RPE,MCMBP,GLDN,PTGR2,TRAPPC13,AP1AR,SAFB,SALL1,CSRNP3,ATXN2,SCN8A,GALNT10,STUM,PPM1E,ASAP3,SHC4,SYBU,FAM81A,SLC6A11,CCDC88A,MTERF2,TET1,EPC1,RCOR3,MAPKBP1,MBD5,LMBRD1,BDP1,NMNAT2,HECW1,TROVE2,ITPRID2,SAMSN1,SS18,DIP2A,KLHL7,ZC3H4,PRRC2C,SYNE2,COBL,TACR1,FAM208A,KIAA1107,KLHL4,DMXL2,ZEB1,TCF12,SLC19A3,PCDHAC2,ARHGAP9,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,C18orf54,TMPO,R3HDM1,RASD2,NPL,TRIO,FAM155A,UGT8,ZIC1,ELFN1,ZNF45,AGMO,ZSCAN26,ANKS1B,SMARCAD1,MEIS3,CADM2,PRDM10,FAM13C,PHTF2,TIGD6,NETO2,SENP7" MicroRNA hsa-miR-302b*:mirSVR_highEffct hsa-miR-302b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-102 6.26E-99 2.15E-101 1.98E-100 256 1417 "KDM5D,KLHL32,GALNT13,PWWP2A,KIAA1211,ADRB2,ZNF608,INTS2,MTUS1,CASKIN1,NME5,C1QTNF3,ALCAM,ABCD2,FAM135A,PITPNM2,OGT,CDC42BPA,ANK2,APBB2,MAGEE2,TNRC6C,PPP4R4,IGDCC4,TMEFF1,ARNTL,RGS20,ZNF583,N4BP2L1,DOCK11,BACH1,ADGRB3,SYNJ1,SCAPER,WASF1,KALRN,PTBP2,ISPD,RUNX1T1,METTL6,TIGD7,CFL2,SRSF11,NRXN3,CLTC,ABCG2,QKI,SLC4A8,ABI3BP,IGDCC3,CNRIP1,PREPL,HINFP,GDA,SNCAIP,CSF1,ARHGEF10,OSBPL3,VCAN,PDE4DIP,APPL1,UBXN2A,DCAF4,RUBCN,DOCK4,HDAC9,GPRASP1,ARHGAP32,EARS2,MATR3,KIAA0586,IST1,PITPNC1,DCTN1,MYEF2,LYPD1,PLPPR4,CHRDL1,NR1D2,CPEB2,CASP8AP2,GOLT1B,ANKRD46,SEMA3D,EEF1D,PHF20L1,MBNL2,EGR3,TENM1,PLEKHA1,CALCRL,TUBD1,LRRC17,GPHN,FAM198B,TAOK3,DLC1,ST3GAL6,CEP78,SLC9B2,FGF13,FGFR1,FGFR3,MEX3B,FOXF2,C2orf88,NBEA,FAM49B,ATP2C1,KHDRBS3,STAU2,ABLIM2,GABRB3,GAD1,C15orf41,DISC1,IGSF5,ADAM28,MALT1,DBF4,SPIN1,TNRC6A,ZNF638,FERMT2,GRIA2,PLCD4,PRDM5,FAM19A2,RNF165,MIER3,HMGCR,HSF2,ZNF546,LRRCC1,JAK2,KIT,CYP27C1,LAMP2,HECTD2,SMAD1,PIK3AP1,LYPLAL1,MEIS1,AFDN,ZNF680,MT1M,P2RY13,NF1,NUCB2,CHAMP1,PAX6,PCDH9,PDCD2,PDE4D,GNG2,SNX10,RETREG1,PURG,ANKRD16,TRHDE,ING3,EPB41L4B,FA2H,PPM1B,PCDHB17P,KANSL1,GRAMD1C,DIRAS2,RELN,SPDL1,TMEM260,ZSCAN32,PTPRB,TMEM231,SH3TC2,NWD1,OXR1,RASGRF2,RBBP8,RADX,KHDRBS2,MSANTD2,PBRM1,ZFHX4,ROBO2,RPL15,LRRK2,RYR3,SUPT20H,SGK1,ZFP30,SHC4,FBXO11,FNDC3A,FHOD3,SEC31A,PPP4R3A,EPN2,FAM214B,RADIL,ATF7IP,SMARCC2,ANKRD36,MBD5,SNRPN,PDZRN3,BDP1,TEX2,ZNF423,ZC3H13,SPTAN1,CDK19,MCF2L2,ATP10B,TROVE2,SSTR2,LARP4,ELOVL4,DIP2A,VPS13A,SYPL1,ATMIN,TCEA1,TRIM2,SIK3,ZMAT3,SLC44A1,ASXL3,ERCC6L2,TNS1,TPM1,METTL3,DCBLD1,RPL7L1,ZNF781,ZNF711,ZNF17,ZNF23,ZNF45,CELF4,FSTL5,EML6,SMARCAD1,UPF3A,MFF,CADM2,KCNAB1,WNK3,PLSCR4,PDSS2,EPM2A,DOCK8,JMJD1C,KLHDC1,RNF146,ST8SIA2" MicroRNA hsa-miR-411*:mirSVR_highEffct hsa-miR-411*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-102 6.81E-99 2.33E-101 2.15E-100 237 1210 "CLK4,NCKAP5,PTCHD1,KLHL13,RTL9,CC2D2A,TAOK1,ALCAM,LRCH2,BCAS1,TNRC6C,ZBTB10,NCOA1,TMEM108,ATP1B3,DPY19L3,SEC11C,AP1M1,SGCE,WASF1,KALRN,MTMR7,CD86,SYNGR3,CDH2,LRRFIP1,LARGE1,MAGI1,DLGAP1,SRSF11,CHN1,NDST3,PLAA,FBXO7,ARMC8,COL4A5,AKAP5,SLC35F1,SEC31B,CLOCK,RBM39,SH2B1,CSNK1G3,PDE4DIP,FAM169A,RIMS2,CCDC144A,CYBB,KATNAL2,LIN54,PABPC5,ELMSAN1,GSDME,SACS,SPOCK3,SEC16A,GRIN3A,DMD,DMTF1,ECM2,EDNRB,FCF1,RASGRP1,FSD1L,YAF2,EIF4G2,TENM1,PLEKHA1,TMEM35A,C8orf37,CALCRL,ENPP6,SRRM1,RRAGB,SEC24B,FER,POLR1B,POLK,SUCO,IP6K2,RGPD5,NELFCD,C2orf88,PDLIM5,ATP6V1H,GABRG2,INPP5K,ARFIP1,PPARGC1A,MALT1,SPIN1,ZNF638,KIAA1958,KDM2B,HTATSF1,ADGRA3,PSIP1,GUCY1B1,MAP4K5,RASSF8,FRMD3,ATXN2L,AGBL5,SMAP1,ZNF678,PAXBP1,HECTD2,MAP4,MBNL1,CHIC1,MEIS1,MEIS2,MITF,MSI1,ADAM22,MYCN,MYO9A,HNRNPM,IDNK,NEFM,NEK1,DNHD1,NRCAM,GLIPR1L2,CNTN3,PRTG,SLC10A4,GNG2,OLA1,SNX10,RETREG1,PMP22,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R2C,PPP3CA,KANSL1,HYDIN,CNTLN,BDNF-AS,TMEM260,PTPRB,PTPRD,C1orf109,PPP2R3C,PID1,USP47,ACSS3,OXR1,KHDRBS2,RDX,GTDC1,FIGN,RFX3,NUDT11,PBRM1,RNASEL,ZFHX4,ZNF532,CARF,RORB,ATP8B4,ADAL,SALL1,SEMA6D,SATB1,SCP2,FNIP1,SUPT20H,SGK1,NLGN1,WDR47,KDM4D,SEPHS1,SLC12A2,ATF7IP,ZFP1,SMARCA4,CMTR2,SNRPN,SOX3,SP4,KDM4C,RBM26,LMO3,ATP10B,TROVE2,NKAIN2,ELOVL4,TTBK2,PHLDB1,SYNE2,VPS13A,SYPL1,MTCL1,CAMTA1,MCF2L,EXOC7,FAM208A,TBCEL,ZEB1,RPGRIP1L,SYNE1,PCDHB10,PCDHB6,PCDHB3,FRYL,PMS2CL,SLC44A1,ASXL3,RGMB,TRO,CLHC1,UBE3A,UGT8,PLEKHH2,WRN,ZNF711,MICU3,KCNT2,TCEAL7,ANKS1B,FTSJ1,CADM2,STOX2,RNF103,ADAMTS9,PDSS2,AMN1,DOCK8,PHTF2,JMJD1C,FXR1,NETO2,NETO1" MicroRNA hsa-miR-221*:mirSVR_lowEffct hsa-miR-221*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-102 7.68E-99 2.62E-101 2.41E-100 295 1879 "DGCR6,NDRG3,ADCY5,ADORA2A,ADRA1B,OSBPL8,AK2,AMT,CDC42BPA,SEMA7A,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,APC,EPB41L5,PCDHGB4,SLC4A4,EIF4G3,DPY19L3,ADAM15,BCHE,RGS9,NRP2,CA4,CA8,LURAP1,CALM1,SLC25A14,CAST,USP6,ARHGEF1,SCARB1,SYNGR3,LRBA,TAOK2,TPP1,FAM189A2,CABP1,SUMF2,LETMD1,SLC4A8,MYRIP,SEC31B,ANKRD44,NCOR1,TRIM69,CSF1,SUSD5,CST3,DZIP3,PPP1R16B,MYADM,HDAC4,EARS2,ZNF337,TBC1D5,TMEM170A,JAKMIP2,RUSC2,KIAA0319,ZC3H11A,GUCD1,SGSM2,WDR20,ZNF582-AS1,NYAP1,MAMLD1,ABCC5,EDNRA,PHC2,CNNM1,RASGRP1,YAF2,EGFR,EIF5,IRAK4,TMEM35A,EPB41L2,RCAN2,STX2,ERBB2,PIPOX,VPS26C,ANKMY1,ADGRV1,EZH1,RPS6KC1,TMEM132C,RACK1,STRADA,FGF1,POLK,SCARA3,HPCAL4,VTI1B,STAMBP,ZNF605,AP4B1,NEURL4,FAM120B,B4GALNT1,ZNF274,DISC1,SEPT9,GCNT2,CYP46A1,GGT7,GHR,CRCP,GNG4,GPT2,WDFY3-AS2,GPD1,GPD2,PRUNE2,LPAR4,GPER1,CACFD1,GRIN2C,ATE1,LINC01089,COQ10A,AP4S1,FAM107A,FRMD5,MIER3,HLF,ELOVL5,DHX35,LRRC75A,RBPJ,KNDC1,SCIN,IL6R,IBA57,SLC35G1,KCND2,KCNN3,A1BG-AS1,L1CAM,MAN2A2,ZFYVE27,MARK1,MBD1,MEIS2,XRRA1,SAMD5,BLOC1S2,NINJ2,VWA2,SLC11A2,NUCB2,P2RX7,TREM2,DPY19L2P2,PCDHGC3,PCDH9,PDE4D,GNG2,SEMA5B,CCSER2,TMEM38A,JAKMIP1,PNMA3,PSAT1,PPM1B,TATDN3,PPP2R5E,MAPK9,WBP1L,CYBC1,TMEM104,CNTLN,PTCH1,FAM66C,SH3TC2,DPF2,PRRT2,RFX3,RGS12,RNH1,PNMA8A,GSTCD,SNX22,RPL15,BAALC,MCMBP,ADAL,STK32B,ATAT1,ZNF568,AP1AR,MAPK12,SCN7A,TNFRSF19,FOXRED1,SCAF8,HKDC1,SYBU,NLGN1,SEC31A,ANKRD6,SLC2A5,PPP4R3A,DHX30,SLC8A1,ARHGEF40,SLC9A5,SLC12A2,ATF7IP,LGI3,SMARCD3,IFT122,FAM126B,PDZRN3,KDM4B,TRERF1,ZSWIM8,NFASC,LARP4,NKAIN2,SSPO,SEPT8,TTBK2,ADHFE1,NSFL1C,PRRC2C,SYNE2,VPS13A,ADAMTS17,ANKRD28,TACC1,CAMTA1,PDLIM2,ADGRL3,SMG6,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PUM2,CYB561A3,DICER1,ITGB3BP,AP4E1,GALNT17,HEY1,ACTR6,BHLHB9,ERCC6L2,CHST5,RGMB,NR2C2,ZNF346,SYNPO2,TRIO,NEIL2,RUSC1,KCNE5,TSN,TUBB1,FLRT2,VLDLR,WIPF1,NPDC1,ZNF19,TRIM9,ATP6V0E2,LYPD6,CELF4,TMEM198,DPYSL5,LAMP5,EMSY,GDPD5,LINC02210,PRDM8,PDSS2,FAM219B,JMJD1C,TRAM2-AS1,TIGD6,ADAMTS10,DPF3,JPH3" MicroRNA hsa-miR-3198:mirSVR_lowEffct hsa-miR-3198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-102 8.23E-99 2.80E-101 2.58E-100 282 1721 "CLK4,XKR4,NDRG3,ADD2,KCTD16,KIAA1324,OSBPL8,TAOK1,ANK2,FGD2,PHF12,APBA2,CDC14B,SEMA4G,MADD,ARNTL,LINC00173,PCDHGB4,NUMB,EIF4G3,ATP2A2,ATP2B2,N4BP2L1,BACH1,ADGRB2,RGS9,SYNJ2,SCAPER,GPC2,CA4,CA12,PTBP2,CAMK2G,SPAG9,NFS1,CBLN1,METTL6,TAOK2,NRXN3,CLTC,MAP4K4,LY86,AKAP6,CABP1,ABI3BP,RCHY1,SMARCAL1,SEC31B,PREPL,CSF2RA,CSNK1E,FAM169A,PHF14,MYADM,ARHGAP32,EARS2,DAPK1,AIF1L,DNAL1,DGCR5,RUSC2,POM121,RHOBTB1,SGSM2,SLC29A4,ARRDC4,DNM1L,PHC2,FCF1,KLHL5,CELSR3,FAM13A,SUGP2,EGFR,MBNL2,IRAK4,USPL1,TUBD1,ETV1,TLR7,SIRPB1,ADGRV1,TMEM132C,ZSCAN30,PPP1R1B,GTF2IRD2,BAIAP2,FHL1,POLK,SEMA4D,PSD2,SLC37A3,NOP56,WDR83,CAMKK2,ATP6V1H,CELF1,SDCBP2,GALNT15,DENND2A,ZNF559,DISC1,SULT1C4,MSTN,GGT5,LYVE1,CRCP,DBF4,GLYR1,MSL3,LNX1,GPD1,PRUNE2,FUT10,GPR12,STON1,PLPP7,GRM2,CIT,RNF165,KAT7,GSTT2,GUCY1B1,FAM222A,UBE2QL1,FRMD5,AGBL5,NEGR1,NKD1,INPP5B,ITGAM,SLC35G1,KCNB1,KCNJ16,GATD1,CREG2,LINC00634,IPO5,SFXN5,CLEC18A,MAN2A2,MAT2A,CHIC1,MEIS2,KITLG,MN1,MPP2,PTOV1,MYO9A,P2RY13,CCDC13,NOVA1,SMIM11A,NTRK2,TBC1D25,OGG1,GLIPR1L2,PCDHGC3,PCSK5,PDE1C,CCSER2,RETREG1,FXYD1,ZNF426,PLXNB1,SDK2,LRRN3,PRKCB,GRAMD1C,DIRAS2,CYBC1,NCR3LG1,ZSCAN32,PTPRE,NWD1,ROGDI,OXR1,RASGRF1,TRIM68,RGS4,ZNF532,SUGCT,TMLHE,C12orf49,KLHDC8A,ARMC5,CARF,ROBO2,ELP2,NEK11,SGSM1,LRRK2,PTGR2,KCNIP3,DGLUCY,MAPK12,SEMA6D,CSRNP3,SCN2B,SCP2,TNFRSF19,SEC14L1,GALNT10,SUPT20H,SH3GL3,AMBRA1,FHOD3,WDR47,FAM214B,KANSL3,PKNOX2,SLC6A11,ARHGEF40,SLC14A1,BTBD7,CDK5RAP2,SMARCD3,MYH15,ANKRD36,SNCA,TMCC1,FAM219A,DOP1A,ZSWIM8,NMNAT2,ARHGAP26,CLSTN2,ZC3H4,SYNE2,ARC,FAM208A,KLHL4,WSCD1,DMXL2,CUX2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PCDHB3,PCDHA5,FRYL,RNF216P1,PMS2CL,SLC44A1,THRA,BEX4,CHST5,RUNDC3B,TRO,TRPS1,PPIL6,TSN,TTTY15,RPL7L1,VIPR2,RICTOR,ZNF708,TCEAL7,DPYSL5,PCBP1-AS1,MEIS3,SLC30A4,CADM2,SIGLEC10,SLC17A7,PCBP4,RGS7BP,FAM13C,MARCH8,DPF3,FAM198A,JPH3" MicroRNA hsa-miR-188-5p:mirSVR_lowEffct hsa-miR-188-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-102 9.41E-99 3.19E-101 2.94E-100 258 1442 "KCNH8,ACADM,NDRG3,ADCY6,TMCC3,ADD2,PWWP2A,MTA3,AP2A2,TBC1D14,AK2,ZNF578,SEMA6A,ABCD2,AMPD2,AMPD3,OGT,LCORL,SUGT1P4-STRA6LP-CCDC180,UPRT,LGR5,SPTBN4,PLA2G4C,SLC4A4,ATP1B3,DPY19L3,ADAM23,BMPR1B,SYNJ1,SYNJ2,JAZF1,CACNA1G,CACNA1A,CACNB4,CALB2,CABP7,SPAG9,CD86,CD38,CDC25B,LOC730101,CFL2,CHN2,MYL6B,IGLON5,PCYT1B,ARMC8,AKAP6,SLC4A8,ZNF521,ZFP28,FAM171B,RBM39,MROH8,SEC24C,CSNK1G3,SIPA1L1,VCAN,PDE4DIP,PLXNA4,DZIP3,CTH,RIMS2,CCDC144A,TCAF1,LONRF1,DNAL1,ELMSAN1,MFAP3L,KIAA0319,GUCD1,SV2B,DMTF1,PDCD6IP,ECM2,MAMLD1,DNM1L,ANKRD46,SUGP2,APH1A,IRAK4,PLEKHA1,ING4,TMEM35A,EIF1,EPB41,EPB41L2,ZNF549,ADGRV1,TMEM132C,ACSL4,CEP78,CHST15,ZSCAN30,PRMT5,FGFR1,POLK,SYNCRIP,AGAP3,RGPD5,ATP13A4,ANKFY1,SLC37A3,AKAP3,SMC2,RASL10A,KHDRBS3,ST6GALNAC3,NSG1,TRAF3IP2,SEPT9,GPR162,CYP46A1,ADAM28,GGT7,GLYR1,TOX3,GLUL,RAB40B,GPD2,STON1,LPAR4,TPPP,DIDO1,FAM19A2,COQ10A,FAM107A,ZHX1,FRMD3,ARHGAP36,ELOVL5,GABARAPL2,AGBL5,HNF4G,DHX35,LRRC75A,SMAP1,IRF8,IL12A,ITGA7,JAK2,METTL21A,GPR62,KIF5A,STXBP5,STMN1,MEF2C,MEIS1,MEIS2,MEST,MITF,AFF1,SAMD5,MSR1,N6AMT1,MX1,MXI1,P2RY13,ZC3H12B,NOVA1,NRCAM,NTRK2,P2RX7,CDK18,PDE4A,PFKFB2,PIK3R1,FAM218A,CCSER2,LRP12,POLR2F,TATDN3,PPP3CA,EPDR1,MAPK9,MASP1,PTCH1,NCR3LG1,PTPN13,PTPRB,FAM66C,ZNF793,RASGRF1,ZDHHC14,UBR7,KIF7,LGI2,GSTCD,CYB561D1,NEK11,ATP8B4,STK32B,CASC3,ARX,FBXO11,FNDC3A,PEX26,KANSL3,PKNOX2,SLC12A2,ELMO2,ATF7IP,TET1,ARFGAP1,MYH15,MBD5,SNRPN,BDP1,ZNF423,CDK19,NFASC,LMO3,POGZ,ITPRID2,ZC4H2,NKAIN2,SS18,ERBIN,CEP68,SYNE2,ARHGEF9,SYPL1,MTCL1,PJA1,FAM208A,MGRN1,SATB2,TCF12,CLASP1,SYNE1,DOCK9,SLC19A3,PCDHB3,FAM200B,DICER1,SIRT1,AMACR,FAM155A,UBE2H,SLC35A4,UBE3A,TBC1D15,VSNL1,PCDH20,MICU3,TRIM9,ATP6V0E2,ZNF74,CELF4,TMEM237,POLR3H,EVI5,PRDM10,HPS4,FAM219B,JMJD1C,SOCS4,LAS1L" MicroRNA hsa-miR-623:mirSVR_lowEffct hsa-miR-623:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-102 1.01E-98 3.42E-101 3.15E-100 292 1844 "SYS1,NDRG3,PWWP2A,KIAA1211,RNF150,FAHD2CP,AP2A2,INTS2,PCDH19,AK2,SEMA6A,SPOP,ABCD2,BEGAIN,AMPD3,AMPH,DPP10,EP400,CCDC146,UPRT,AQP6,IGDCC4,SPTBN4,ARHGDIA,ARRB2,NUMB,SLC4A4,DPY19L3,ADAM23,LINC00847,SEC11C,JAZF1,GYG2,LDLRAD4,CACNA1A,CALM1,PTBP2,CAMK2B,VXN,SLC16A4,UBE2L6,CFL2,CHGB,CHN2,RAB33A,CLCN3,TPP1,AKAP7,IQCK,PCYT1B,ARMC8,FAM149A,COL4A5,SUMF2,SMARCAL1,CLOCK,C2CD2,RBM39,NCOR1,GDA,MROH8,CSNK1E,SIPA1L1,PLXNA4,DZIP3,DCAF4,CCDC144A,BOC,DCAF8,EARS2,LONRF1,DGKG,SCRN1,BRINP1,SPATA2,KLHL3,ZNF582-AS1,DNM1,SLC29A4,DMTF1,DPYSL2,SLC25A18,ACOT8,DNM1L,EBF1,SNX29,HEYL,FRY,MRO,AASS,TENM1,CALCRL,RCAN2,SRRM1,NCALD,CEP85L,ZNF549,DNAJC27,ADGRV1,ACSL4,ZMYND10,PRMT5,KAT8,GTF2IRD2,FGF14,POLK,SUCO,HPCAL4,FOXO3,SEMA4D,ATP13A4,FLT1,SLC37A3,NBEA,SPECC1,PDLIM5,FAM49B,ATP6V1H,KHDRBS3,ABLIM2,OGA,GABRG1,GAD1,ERAP1,SEPT9,USP19,GGT7,ZNF276,COPS8,GLYR1,RAB30,TOX3,TNRC6A,GLUL,ZNF638,KDM2B,LUZP2,RAB40B,SPACA9,SERP2,FAM19A2,COQ10A,AP4S1,GUCY1A1,IRAK3,HAS2,FRMD5,TNFAIP8L3,CPT1C,DHX35,SMAP1,IRF8,FAM95B1,MYLK2,IL12A,ZNF678,INPP5B,INSM1,JAK2,GPR62,KIF5A,STMN1,HECTD2,MEF2C,MGAT3,MID1,AFF1,AFDN,MT1M,MXI1,MYO7A,MYO9A,NFYA,DNHD1,SLC11A2,NRCAM,NTRK2,NTRK3,LOC100128398,OXTR,PCDH9,PCSK5,CDK18,NLGN3,TMIE,ZNF655,FAM216A,PLCL1,ANKRD16,LRP12,POLR2F,DRAM2,MINDY2,PPM1B,PPP2R5E,PRKAB2,PRKCB,MAPK4,EPDR1,MAPK9,MASP1,CNNM2,PIGG,NCR3LG1,PTX3,CEP97,ZNF793,RADX,ZDHHC14,ZMAT4,DPF2,RGS12,KIF7,RIC8B,ZFHX4,ROBO2,FBXW7,SGSM1,ADAL,PRCD,ZNF821,TRA2B,SH3GL3,FRMPD1,ARX,FERMT1,KIF16B,AMBRA1,SEC31A,KANSL3,CCDC88A,SLC14A1,ATF7IP,MYH15,SNRPN,BDP1,HECW1,MYCBP2,KDM4C,ZNF423,SPART,NFASC,ATP10B,SS18,ERBIN,ZSCAN29,DIP2A,ADHFE1,SEPT3,NSFL1C,ARHGEF9,MTCL1,PJA1,CAMTA1,CUX2,ZEB1,TPCN2,SYNE1,NAT16,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,SIRT1,C18orf54,ZNF106,AMACR,TSN,TTTY15,BCL2L13,VSNL1,GUSBP1,MICU3,POLR3H,ANKS1B,DHX33,SLC38A1,GDPD5,PRDM8,TMEM178A,FAM13C,FZD3,MARCH8,UBE3B,FBXO36,FAM219B" MicroRNA hsa-miR-1202:mirSVR_lowEffct hsa-miR-1202:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.05E-102 1.71E-98 5.74E-101 5.28E-100 281 1714 "RALGAPA1,KCNH8,NCKAP5,ADD2,BRAP,ADORA2A,KIAA1211,RNF150,ADRB2,AP2A2,CC2D2A,HFM1,SMIM17,ZNF687,PDZD4,DOC2A,OGT,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,UPRT,BCAS1,PPFIA3,SFMBT2,SPTBN4,ZFYVE28,PLA2G4C,LINC00173,CHRD,INSYN2B,TMEM108,ADGRB3,MIR9-3HG,BCL7A,KSR1,BMP7,DST,CASTOR3,JAZF1,SGCE,CFAP410,CA8,CALM1,CH25H,HIP1R,NFS1,CD38,CCPG1,CHN1,CNOT8,NDST3,TPP1,HECTD1,CNR1,SUMF2,COL9A1,SMARCAL1,BAG4,SEC31B,HAPLN1,CS,SEC24C,CSNK1E,DZIP3,PUM1,RUBCN,CYBB,ARHGAP24,INTS1,ELMSAN1,ELMO1,B3GAT3,RUSC2,PLPPR4,SGSM2,WDR20,ZNF582-AS1,RAB39B,DPH1,DTNA,PHC2,PLXNC1,TMEM132E,RCAN2,SRRM1,ERBB2,ETV1,FDFT1,KAT8,AMOTL2,FOXF2,SYNCRIP,EVL,SEMA4D,ATP13A4,NOP56,EFCAB2,HVCN1,DOT1L,OGA,MEGF11,GAA,HRASLS5,GABRA3,TUBGCP4,SRCAP,ARFIP1,GHR,MALT1,CRCP,AIFM3,DCLK2,GPD1,GPD2,PRUNE2,C1QL4,ADAMTS13,GRM2,PRDM5,LINC01089,FAM19A2,GSTM5,SOX21,ADAMTS6,FAM222A,FRMD3,ARHGAP36,HMGCL,ZDHHC15,TCEAL6,SHISA6,SMAP1,FAM95B1,ZNF678,KIFC3,IPO5,ZFYVE27,MAPT,ADAM11,MID1,MITF,AFDN,MSR1,NRBP2,NF1,NFE2L2,NOVA1,DNHD1,NUCB2,P2RY1,CDK18,PDE1B,PFKFB4,ZDHHC8,DUSP26,SEMA5B,XRN1,NLE1,PLTP,MAPKAP1,LRP12,SCHIP1,SDK2,SEPT4,POLR2F,MINDY2,KANSL1,NKAIN4,VSTM2L,MASP1,APTX,GDPD2,MTMR10,TMEM260,STK32A,PTPRE,C1orf109,PEX2,NKAIN1,SLC25A48,TRIM68,RGS12,GSTCD,CYB561D1,ROBO1,MRAP2,SNX22,EPHA10,GLDN,TCP11L1,MEG3,KCNIP3,SALL1,SATB1,SCP2,TNFRSF19,ZFP30,FAM102A,FERMT1,HKDC1,CHD9,FNDC3A,R3HDM2,SLA,PREX2,BTBD3,DHX30,WDR47,SLC6A11,ELMO2,BTBD7,ATF7IP,CPEB4,CDK5RAP2,LIMCH1,FAIM2,SNRPN,DOP1A,FNBP1,ZSWIM8,NMNAT2,KDM4C,ZNF423,CDK19,ZBTB43,NFASC,CLASP2,LARP4,NKAIN2,ST5,RGL1,DIP2A,KLHL7,PRRC2C,ARC,MMS19,MTCL1,ALG1,ADGRL3,MGRN1,ZEB1,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,FRYL,RNF216P1,SIRT1,ZFPM2,AP4E1,RELL2,TK2,FAM124A,RIMBP2,CSMD1,WBP2,UBTF,GORASP1,PLEKHH2,BCL2L13,NPDC1,XRCC4,ZNF28,TRIM9,ZNF540,ZNF70,CELF4,TMEM237,SPIRE1,EMSY,MFF,SLC38A1,STOX2,ST7,UBE3B,FXR1,NETO1,JPH3" MicroRNA hsa-miR-1302:mirSVR_lowEffct hsa-miR-1302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.22E-102 1.80E-98 6.05E-101 5.57E-100 265 1526 "ACADM,KDM5D,NDRG3,NDRG2,TMEM132B,ADD2,PTCHD1,FAHD2CP,C1QTNF3,ALCAM,PCDH10,EP400,FGD2,CCDC146,LCORL,PPFIA4,PHF12,DDO,VAT1L,LGR5,CDK10,SFMBT2,SEMA4G,IGDCC4,ARHGDIG,ARRB2,SLC4A4,SLC2A11,ALDH7A1,ATP6V0A1,KIF1A,ADAM23,MPDZ,SEC11C,RGS11,RGS9,BID,CFLAR,AP1M1,CACNB4,CARS,SPAG9,METTL6,USP6,AP4M1,CDC25B,TIGD7,CCPG1,NOG,DIS3L,PLEKHB1,MAP4K4,FHL5,IQCK,AKAP6,SUMF2,TBPL1,SMARCAL1,NECTIN3,SLC35F1,AKAP12,CRY2,SNCAIP,OSBPL3,VAC14-AS1,PDE4DIP,PITPNM3,ERC2,KIAA0408,BOC,ARHGAP32,DCAF8,CENPL,GIT2,ELMSAN1,RUSC2,C2CD2L,POM121,DMD,SLC29A4,CDON,DPH1,PDCD6IP,MAMLD1,E2F6,PHC2,PHF20L1,SUGP2,TNK2,C3orf18,CALCRL,DCTN4,ENO2,COQ7,LRRC17,RAB9B,IGSF6,CEP85L,ZNF549,MRPL37,EZH1,NSRP1,TBC1D16,TAOK3,DLC1,CHST15,FKTN,MED12L,FGF14,IP6K2,EVL,PSD2,NELFCD,C2orf88,EFCAB2,UFM1,ATP2C1,ERGIC3,CELF1,FYN,GABRB3,TRAF3IP2,DENND2A,GCK,ALDH1L1,GCNT2,PPARGC1A,ZNF276,COPS8,GPT2,ADGRA3,GPD2,ADAMTS13,CACFD1,GRM2,ZBTB49,AP4S1,SLC2A6,ATOH8,IRAK3,PADI2,ATXN2L,ICA1,MSL1,LRRCC1,DISP2,ITGA7,METTL21A,KCNK3,KCNN3,CREG2,TTYH2,MAP4,ADAM11,MEIS1,MEST,KCTD6,SCAMP5,AFF1,MN1,DBNL,MSI1,ZNF862,NNAT,NOVA2,OGG1,P2RX7,PAX6,PDE4A,GPSM2,FAM216A,PURG,PNMA3,EXOSC10,SCHIP1,ING3,RETREG2,SEPT4,FSD1,PCDHB17P,GRAMD1C,PTCH1,ANKHD1,PTPRD,PTPRE,CASTOR1,PTPRN,CEP97,FAM66C,NWD1,RASGRF2,PRIMA1,SETD5,ARMC5,ROBO1,RPE,FBXW7,KIAA0895L,MCMBP,ADAL,ST6GALNAC6,ZNF354C,DGLUCY,ATXN7,PRCD,SCP2,PEAR1,STUM,SHC4,FNDC3A,PEX26,NAPB,SMARCD3,INAVA,CABCOCO1,FAM219A,PDZD2,BDP1,ZSWIM8,ZBTB43,ATP10B,SSTR1,ZC4H2,LARP4,STAC2,ADHFE1,SYN1,SYN2,COBL,PDLIM2,SATB2,RPGRIP1L,TCF12,NAT16,PUM2,USP32P1,CYB561A3,FAM200B,C18orf54,FAM124A,TNS1,TPM1,C9orf85,TTTY15,RPL7L1,UBE3A,VLDLR,P2RY12,CLIP2,RICTOR,GUSBP1,NDRG4,LYPD6,SPIRE1,EMSY,PRTFDC1,DNALI1,GDPD5,FIP1L1,ITM2C,FBXO36,JMJD1C,FRMD6,IFT88,SPATA13" MicroRNA hsa-miR-510:mirSVR_lowEffct hsa-miR-510:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-102 2.03E-98 6.77E-101 6.23E-100 292 1849 "SYS1,KLHL32,ADD2,PLEKHH1,ADORA2A,RNF150,ESYT2,ADRA1D,LRFN2,BEND6,SLC24A4,AP2A2,PCDH19,KIAA1324,CC2D2A,SEMA6A,SPOP,PCDH10,AMPD2,ANK2,EP400,PPFIA3,MADD,MARCH3,INSYN2B,EIF4G3,RIPK1,ADAM23,BACH1,SEC11C,MYRF,CACNA1B,PTBP2,CAST,HIP1R,PRC1,CBR1,ZNF501,METTL6,USP2,ARHGEF1,ZNF445,NUMBL,NDST3,FAM19A5,SUMF2,LRRC3B,CSNK1G3,SIPA1L1,PDE4DIP,PHACTR3,PHF14,GREB1,PUM1,CCDC144A,DOCK4,DCAF8,RASSF2,TM9SF4,TMEM170A,SCRN1,PITPNC1,SPATA2,HEPH,KIAA0753,SV2B,TMCC2,ZNF582-AS1,DMD,ARRDC4,DTNA,DNAJB6,AASDH,EDIL3,RASGRP1,FAM13A,APH1A,EGFR,EGR3,TMEM132E,DCTN4,ENPP6,KATNAL1,MRVI1,CLVS1,ZNF461,SCML2,FCGRT,ZSCAN30,FDFT1,ZNF589,FER,FGF11,FGFR1,FHL1,UBE2E3,SEMA4D,ERGIC3,CELF1,FYN,ZNF274,GHDC,SRCAP,SULT1C4,GPR162,GGT7,PPARGC1A,TTBK1,CRCP,DBF4,TOX3,DCLK2,SPACA9,RNF165,ZBTB49,BVES,SOX21,PSIP1,ADAMTS6,HLF,HMGCL,HNMT,NEGR1,CPT1C,SHISA6,EID2B,IRF8,IDH3A,LRRC25,SLC6A17,INSM1,ITGAM,KCNB1,STMN1,SYTL4,HECTD2,GPR155,MAP6,MEIS1,KITLG,PPM1L,AFDN,XRRA1,MN1,ZNF680,SAMD5,ADAM22,MSR1,MYO6,ZNF862,HNRNPM,NELL2,ALDH1L2,NOVA1,DNHD1,SLC11A2,NTRK2,NTRK3,NUCB2,TBC1D25,CLDN11,ZNF713,GLIPR1L2,PCSK1,CDK18,ENPP2,PFKFB4,NALCN,PIK3C2A,ZFYVE21,XRN1,PLCD1,ANKRD16,SDK2,NECAB2,PPM1B,TATDN3,GRAMD1C,BCAS3,VPS13C,WBP1L,CYBC1,APTX,MTMR10,ZIK1,PTPRG,C1orf109,TUG1,QDPR,FAM66C,ZNF493,RASGRF1,RASGRF2,CRTAC1,TRIM68,RNASE1,RIC8B,RNASEL,CARF,YY1AP1,MRAP2,EPHA10,GLDN,RPS20,KCNIP3,SEMA6D,SBF1,ATXN2,PRCD,TRA2B,COPZ1,KIF16B,SHMT2,FNDC3A,SEC31A,DZIP1,ST8SIA1,ANKRD6,DHX30,KDM4D,ARHGEF40,CCDC88A,TRIM67,LGI3,ZKSCAN3,ANKRD36,CABCOCO1,SNRPN,FAM126B,SOX3,TSNAXIP1,FNBP1,NMNAT2,HECW1,MYCBP2,KDM4C,SPTAN1,IQSEC2,MCF2L2,NFASC,ZC4H2,STAU1,VPS13A,SYN2,SYT1,TAL1,FAM208A,ALG1,TCF4,CLASP1,DOCK9,SLC19A3,PUM2,FRYL,DICER1-AS1,AP4E1,TIAM1,MTMR14,NACC2,PIK3R5,RASD2,ZNF346,SYNPO2,METTL3,SMUG1,ELP5,TRPS1,BCL2L13,PLPPR2,ZNF19,ZNF28,TRIM9,LYPD6,UPF3A,SLC30A4,GDPD5,LINC02210,STOX2,SLC17A7,WNK3,PLSCR4,FZD3,DOCK8,UBE3B,KAT6A,PHTF2,ADAMTSL3,TTC7A,FXR1,GAN,FAM198A,SENP7" MicroRNA hsa-miR-502-5p:mirSVR_lowEffct hsa-miR-502-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.20E-102 2.35E-98 7.82E-101 7.20E-100 288 1801 "KCNH8,ABHD6,EMILIN3,NCKAP5,NDRG3,GALNT16,TMCC3,ADD1,AP2A2,FAM135A,AMPD2,CCDC146,SUGT1P4-STRA6LP-CCDC180,PARG,PPFIA3,RGS20,MARCH3,NUMB,EIF4G3,CARMIL3,LDHD,C5,IL33,CALM1,VXN,CARS,RUNX1T1,CBR1,CBS,RGN,CD38,ZBED1,CLGN,NUMBL,COPB2,CHN2,LHX2,RAB28,PPT2,TPP1,MYL6B,DGCR9,TMEM184B,MAP4K4,AKAP6,RCHY1,COX4I1,IGDCC3,CPS1,C2CD2,ANKRD44,RGS6,FAM169A,CTH,ARHGAP32,KIF26A,DGKG,SCRN1,IP6K1,GIT2,ZBTB24,RUSC2,KIAA0319,KLHL3,CHRDL1,SLC12A6,CASP8AP2,ACOT8,ECM2,MAMLD1,FCF1,HEYL,EGFR,CERCAM,ELN,C3orf18,EPB41,EPHB1,ENPP6,ERCC2,DENND4A,MRPL10,ADGRV1,REEP2,TAOK3,RACK1,ZNF589,FER,FGF1,FGF13,POLK,UBE2E3,SEC23B,PCYOX1,SYNCRIP,SEMA4D,WDR83,TMEM107,ZBED3,APOPT1,ZNF605,PRELID3A,DLL3,TPPP3,DOT1L,ZMAT1,MEGF11,MEGF10,ERAP1,DISC1,ALDH1L1,CYP46A1,ADAM28,PPARGC1A,LYVE1,RUNDC3A,ZNF276,CRCP,GLI2,TNRC6A,KDM2B,LOXL3,GPD1,GPD2,PCLO,STMN2,TPPP,GRIA2,PRDM5,CLASRP,SLC2A6,MAP4K5,HAS2,TOX2,C9orf129,MYLK2,RBPJ,NIM1K,A1BG-AS1,LAMP2,PACRG,CLEC18A,ZFYVE27,MATK,MATN3,MBNL1,MBP,TM6SF1,MEIS1,SRSF12,KCTD6,SCAMP5,PTOV1,HS6ST3,RTL5,NEFH,NF1,ALDH1L2,NFYA,SLC11A2,OCRL,P2RX7,ZNF827,PCSK5,SERPINI1,PLCB2,PNMA3,STRN3,PSAT1,ING3,RETREG2,EPB41L4B,CCDC144B,PPP3CA,PRKAB2,PIGG,CNTLN,BDNF-AS,ZIK1,PTPRB,C1orf109,NKAIN1,PPP2R3C,ZNF793,ENOX1,RASGRF2,RIC8B,RNASEL,DCUN1D2,RORB,ZC3H14,GLDN,MEG3,ABCA11P,ATAT1,RMI1,PRCD,TRA2B,SCAF8,ZFP30,SH3GL3,CNKSR2,FAM214B,SLC6A8,SEPHS1,SLC8A1,SLC9A5,SLC14A1,SLC22A4,EPC1,SMARCD3,CABCOCO1,SNRPN,USP33,DOP1A,KDM3A,ZSWIM8,ERC1,UNC5B,SPTB,CDK19,SPART,ELOVL4,CEP68,DIP2A,STAC2,ADHFE1,KLHL7,ANKRD12,WSCD1,TCF4,CLASP1,NAT16,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,FAM200B,PMS2CL,C18orf54,AP4E1,AKTIP,CDH22,MTMR14,TMEM9,TLR4,RIMBP2,R3HDM1,CDK20,NPL,CHST5,SYNPO2,METTL3,ELP5,TRIO,NEIL2,DCBLD1,UBE3A,BCL2L13,VLDLR,WIPF1,XRCC4,ZNF19,TRIM9,ATP6V0E2,TMEM237,POLR3H,FTSJ1,DNALI1,SLC38A1,GDPD5,LINC02210,MDH1B,ITM2C,FAM47E,FZD3,DOCK8,HNRNPA3,PHTF2,FAM219B,TIGD6,RNF170,IFT88" MicroRNA hsa-miR-584:mirSVR_lowEffct hsa-miR-584:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.83E-102 3.26E-98 1.08E-100 9.98E-100 259 1461 "ABHD6,TMEM132B,BRAP,HECW2,WDR35,SMIM17,ARHGAP20,PCDH10,BBOX1,UNC79,UPRT,USP37,TMEM108,DPY19L3,MPDZ,BCHE,BID,ZNF599,CACNB4,KALRN,PTBP2,VXN,ISPD,CCNH,MTMR7,SLC16A4,CDH2,ZMYM4,LRRFIP1,LOC730101,ZNF445,MAGI1,DLGAP1,CFL2,COPB2,SRSF11,B4GALT6,NDST3,NRXN3,PPT2,CLTC,FAM19A5,IQCK,ABI3BP,IGDCC3,CREM,ENTPD4,SNCAIP,CSF2RA,LRIG1,LRRC3B,SIPA1L1,PLXNA4,DZIP3,APPL1,PLCXD3,BOC,KATNAL2,ARHGAP24,KIAA0586,KCTD8,TMEM170A,SCRN1,PABPC5,GIT2,DNAL1,ARMCX2,ZNF804A,KLHL3,ALKBH8,WDR20,DMD,CASP8AP2,EDN1,SEMA3D,GOLGA7,TENM1,USPL1,GPHN,STX2,ETV1,ADGRV1,F5,CLVS1,ZNF461,ACSL4,ST3GAL6,CEP78,FKTN,FECH,FER,FGF1,OLFM1,FGF12,POLK,FOXF2,PCYOX1,SYNCRIP,FOXO3,NBEA,SMC2,ERGIC3,CSPG5,MEGF10,RAPGEF6,ZNF559,DISC1,GATM,ADAM28,USP19,GHR,LYVE1,TOX3,TNRC6A,ZNF638,CBX1,LUZP2,KCNMB4,PCLO,GRIN2D,ZBTB49,ZDHHC15,USP51,NEGR1,LRRC75A,RBPJ,IL6ST,METTL21A,STXBP5,HECTD2,NCOA7,PACRG,PIK3AP1,MEIS1,PPM1L,AFF1,ADAM22,LYRM9,MYO9A,ZNF862,TCEAL5,BEX5,HNRNPM,ALDH1L2,NME4,CNOT4,NTRK2,IGSF11,OCRL,CLDN11,ZNF827,GLIPR1L2,CNTN3,PCSK5,PDE4D,SERPINI1,PIK3R1,SLC25A23,MTRF1L,PURG,LRP12,PSAT1,IRX1,PPP2R5E,PPP3CA,EPDR1,GRAMD1C,DCHS2,BCAS3,CNTLN,BDNF-AS,TMEM260,PTPRE,ZNF493,KHDRBS2,RDX,GTDC1,RFX2,KIF7,ROBO1,ELP2,NEK11,RPL15,SPIN3,LRRK2,ABCA11P,NCBP3,SATB1,FNIP1,SH3BGR,CPEB3,FBXO11,NLGN1,SLC6A11,SIRT2,ATF7IP,CDK5RAP2,KIF13A,LMBRD1,USP33,KDM3A,ERC1,RBM26,LMO3,TROVE2,STAU1,SEPT8,NECAB1,PRRC2C,PLCB1,TACC1,CAMTA1,TAF9,CUX2,TRIM2,TCF12,GPRIN3,PCDHA5,FAM200B,ZNF106,TIAM1,TK2,TLR4,PARD3,KAT6B,PIK3R5,DOK6,RGMB,SMUG1,AMACR,STXBP4,ANKRD20A2,TTC3,PRR18,ZKSCAN5,UBE2H,UBE3A,FLRT2,PLEKHH2,USP1,ZNF709,CLDND1,ZIC2,ZNF711,ZNF24,ZNF138,REEP1,ZNF189,ZFAND5,UPF3A,DHX33,CADM2,PRDM10,FZD3,UBE3B,PHTF2,NLRP3,FRMD6,NETO1" MicroRNA hsa-miR-222:mirSVR_lowEffct hsa-miR-222:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.30E-102 3.53E-98 1.17E-100 1.08E-99 254 1405 "CLK4,NCKAP5,SYS1,NDRG3,TMEM132B,TMCC3,PTCHD1,BEND6,SLC24A4,OSBPL8,SMIM17,CEP126,BBOX1,AMPD3,LRCH2,MAP4K3,PHF12,PKP4,SEMA4G,TMEFF1,STK33,INSYN2B,ATP1A1,ATP2A2,KSR1,SYNJ1,ARHGEF7,SCAPER,MTMR3,CALM1,PTBP2,LDB2,CD38,CDH2,LARGE1,SRSF11,CHGB,CHN2,NRXN3,FBXO7,AKAP6,SLC4A8,ABI3BP,ZNF521,CNRIP1,ZNF385A,CPS1,RBM39,CRHBP,NCOR1,CSF1,ARHGEF10,OSBPL3,SUSD5,SOCS5,SLITRK5,UBXN2A,PLCXD3,MATR3,MAML1,BRINP1,DBN1,YTHDC1,DGCR5,DDX46,SGSM2,DLX1,DYNC1I1,CDON,DMTF1,CASP8AP2,DTNA,DNAJB6,ABCC5,DNM1L,E2F5,WDPCP,HIPK3,RASGRP1,KLHL5,FRY,YAF2,FAM13A,EIF5,EIF1,RCAN2,ERBB4,DENND4A,RRAGB,FAM198B,TMEM132C,CEP78,FKTN,GTF2IRD2,FGF14,UBE2E3,MEX3B,SYNCRIP,FOXO3,SLC37A3,STAMBP,CGREF1,GABRG1,IGSF5,TCERG1,RNPS1,GLI2,TNRC6A,ZNF638,GNAO1,PRRC2B,PRUNE2,GPR12,GRB10,PLCD4,CIT,ZHX1,FRMD5,HLF,AGBL5,HNF4G,NEGR1,AGFG1,MYLK2,IGF1,INPP5B,SLC6A17,KCNJ16,KCNQ3,CREG2,IPO5,CYP27C1,MAP6,ADAM11,MEST,KCTD6,MITF,AFF1,COL28A1,ZNF862,CNOT4,NRCAM,NTRK2,TBC1D25,OGG1,ZNF713,GLIPR1L2,DPY19L2P2,ETFRF1,PCDH8,PCDH9,PCSK1,OLA1,PIK3R1,ZNF655,LRP12,PPM1B,KANSL1,PRKAB2,DIRAS2,GDPD1,CNTLN,PTK2,PTPN13,EML5,PTPRH,C1orf109,PTX3,USP47,ENOX1,RBBP6,RBBP8,MSANTD2,REV3L,GTDC1,FIGN,LGI2,TMLHE,C12orf49,RTN1,SEMA6D,SATB1,KIF21A,FHOD3,ST6GAL1,ST8SIA1,SLC6A11,SEPHS1,SLC11A1,ATF7IP,ANKRD36,SNAP25,MYO16,USP33,BDP1,SOX11,KDM3A,SPP1,CDK19,ITPRID2,NEK4,SEPT8,RGL1,STX1A,SULF2,PLCB1,SYPL1,SYT1,TACR1,DNMBP,PDLIM2,ADGRL3,KLHL4,CUX2,TRIM2,FRYL,CCDC173,SIK3,RNF216P1,PMS2CL,DICER1,SIRT1,C18orf54,GPR161,TIAM1,TMPO,RIMBP2,KAT6B,STXBP4,UGT8,ZNF781,CLDND1,XRCC4,ZBTB14,ZNF24,ZNF74,TMEM237,AMZ1,ANKS1B,ZFAND5,EMSY,MFF,STOX2,PRDM10,ADAMTS9,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,FAM219B,RSPRY1,SOCS4,SENP7" MicroRNA hsa-miR-567:mirSVR_lowEffct hsa-miR-567:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.35E-102 4.67E-98 1.54E-100 1.42E-99 282 1733 "SYN3,CLK4,KLHL32,ADCY8,PWWP2A,ESYT2,BEND6,MTA3,KLHL13,OSBPL6,FAM135A,ANK2,SEMA7A,EP400,CCDC146,PHF12,UPRT,CPNE5,CASK,TMEFF1,MARK4,NCOA1,TMEM108,SLC4A4,ATP6V0A1,RIPK1,BBS2,MPDZ,BCHE,RGS11,BID,BMPR1B,SGCE,CACNB4,CAMK2G,CH25H,SPAG9,CERS5,CCNH,ARHGEF2,NUMBL,CACNA2D2,SRSF11,SOCS6,NDST3,HECTD1,COL4A5,ABI3BP,BAG4,ZFP28,SEC31B,CLOCK,CREM,GDA,LRRC3B,PDE4DIP,CNTNAP2,SLITRK5,PLCXD3,RIMS2,HDAC9,MYADM,ZNF337,TBC1D5,DGKB,ARMCX2,JAKMIP2,CHRDL1,GRIN3A,RAB39B,CDON,SLC12A6,SNX29,KLHL5,YAF2,FAM13A,PHF20L1,EIF5,RGS17,PAN3,LRRC17,RABEPK,SRRM1,ZNF549,ETV1,KATNAL1,F5,F8,SCML2,CEP78,FKTN,FECH,SLC9B2,OLFM1,POLR1B,FGF13,MEX3B,SEC23B,IP6K2,SYNCRIP,RGPD5,ANKFY1,SLC37A3,C2orf88,PDLIM5,ATP6V1H,KHDRBS3,CHL1,GAD1,ERAP1,ARFIP1,ADAM28,FREM1,TCERG1,GLI2,KIAA1958,DCLK2,GNAO1,PCLO,DIDO1,BTN2A1,RNF165,GSTM5,LINGO1,GUCY1B1,MAP4K5,FRMD3,BACH2,AGBL5,ZDHHC15,TCEAL6,DHX35,ZNF546,LRRCC1,KCND2,LAMP2,STMN1,MAP4,MATN3,CHIC1,TM6SF1,SHC3,MEIS1,SCAMP5,MMP16,COMMD5,BLOC1S2,ADAM22,MYO9A,CNOT4,NTRK2,GPR137C,CNTN3,DPY19L2P2,PFKFB2,NALCN,ZNF655,FAM216A,PCDH18,PURG,PMP22,EXOSC10,ING3,FA2H,PPM1B,PPP2R2B,LRRN3,KANSL1,PRKAB2,CNNM2,SNRK,PIGG,CNTLN,BDNF-AS,PTN,PTPRG,PTPRH,PTX3,ACSM5,USP47,ZNF493,ZMAT4,REV3L,MORC4,GTDC1,UBR7,PRIMA1,SLC25A36,RIC8B,PBRM1,ZFHX4,RPE,NEK11,ZNF671,MCMBP,GLDN,LRRK2,MEG3,ABCA11P,HSD11B1L,KCNIP3,SEMA6D,ZFP2,TRA2B,SCAF8,ARX,FERMT1,CPEB3,FNDC3A,R3HDM2,PEX26,PPP4R3A,DHX30,ZNF430,SLC14A1,CPEB4,ZFP1,ZNF667,LIMCH1,MBD5,DOP1A,BDP1,MYCBP2,RBM26,SPART,PBLD,CLASP2,ITPRID2,SAMSN1,SSTR1,ZC4H2,SS18,STAU1,ELOVL4,RGL1,SULF2,NECAB1,ARHGEF9,TACC1,FAM208A,KIAA1107,TBCEL,SATB2,PCDHB15,SLC19A3,C18orf54,TLR4,KAT6B,RUNDC3B,STXBP4,SSBP2,TTTY15,ZNF610,WIPF1,XRCC4,PCDH20,ZNF17,ZNF24,MICU3,LYPD6,CELF4,ZBTB38,REEP1,FSTL5,SPIRE1,EMSY,EVI5,ADAMTS9,MDH1B,NAV3,EPM2A,DOCK8,KAT6A,SMIM8,TIGD6,RNF170,IFT88,NETO2,NETO1,SOCS4,GAN,ZNF30" MicroRNA hsa-miR-3157:mirSVR_lowEffct hsa-miR-3157:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.30E-102 5.20E-98 1.71E-100 1.58E-99 295 1893 "DGCR6,ABCF1,ACTN1,PSMG3-AS1,ADCY6,TMCC3,ADD2,ADORA2A,FAHD2CP,BEND6,AP2A1,PCDH19,CC2D2A,TAOK1,SPOP,FAM135A,AMPD2,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,PARG,BCAS1,CDC14B,IGDCC4,SPTBN4,ZBTB10,TMEM108,ATP2A2,ATP2B2,SLC2A11,ADAM15,LINC00847,BBS2,DNAJC27-AS1,DST,GPC2,CA8,CACNA1B,DDR1,CALM1,KALRN,CAPN3,CAST,HIP1R,RUNX1T1,CBR1,KYAT1,SCARB1,AP4M1,DCLK1,ARHGAP33,RCBTB2,RAB33A,NRXN3,PLAA,PPT2,CLTC,NGEF,FBXO7,RAB26,IQCK,ABI3BP,ZFP28,ANKRD44,GDA,RGS6,CSF2RA,ARHGEF10,OSBPL3,SUSD5,RIMS4,PHF14,DCAF4,HDAC9,ARHGAP32,HDAC4,DAPK1,SPOCK2,SPATA2,YTHDC1,ELMSAN1,HEPH,MYEF2,DDX46,POM121,SNAP91,SACS,SV2B,SEC16A,GRIN3A,SLC29A4,DMTF1,PDCD6IP,MAMLD1,WDPCP,PHC2,TMTC1,FRY,SUGP2,APH1A,MBNL2,AASS,TENM1,C8orf37,VPS13B,ZNF549,CLVS1,FAM198B,PTK2B,DLC1,FCGR3A,FCGRT,STRADA,MED12L,FGF14,TMEM164,AMOTL2,MEX3B,IP6K2,SYNCRIP,NOP56,DCTN2,FAM49B,OGA,MEGF10,TRAF3IP2,GAD1,ZNF274,LRRC37A6P,GCNT2,TUBGCP4,SULT1C4,MSTN,USP19,PCDH17,GGT7,PPARGC1A,TNRC6A,LUZP2,DCLK2,ADGRA3,PRUNE2,STON1,GPER1,CNTRL,GRIN2C,GRM2,BTN2A1,AP4S1,RABL2A,RNFT2,GUCY1A1,MAN1B1,SYNPO,AGBL5,HNMT,NEGR1,LRRC75A,MSL1,RBPJ,KCND1,STXBP5,LAMP2,PAXBP1,HECTD2,ZFYVE27,MAP2,AQP11,MBNL1,MBP,AFF1,AFDN,MOV10,BLOC1S2,RTL5,NEXMIF,HNRNPM,NBL1,NEK1,NELL2,NF1,SLC11A2,SMIM11A,P2RX7,PCDH9,PCSK1,ENPP2,GPR85,OLA1,NALCN,SEMA5B,TMIE,PLCB2,EXOSC10,ING3,SEPT4,DRAM2,MINDY2,CCDC144B,PPP3CC,PRKAB2,MAPK10,SLC26A11,CNNM2,QRICH1,BDNF-AS,PTPRE,PTPRO,TUG1,ENOX1,RDX,RGS3,RGS4,RGS12,CCDC102B,RPE,NEK11,GLDN,SGSM1,RPS6KA2,MAP6D1,RTN1,TRAPPC13,SATB1,ATXN2,SCP2,PEAR1,KIF16B,FNDC3A,EPN2,SLC22A4,ZNF667,DMRTC1,IFT122,FAM126B,KDM4B,ZNF423,SPART,NFASC,LMO3,TROVE2,ITPRID2,STAU1,ZSCAN29,KANK1,SYNE2,COBL,TACR1,PDLIM2,TBCEL,TBL1X,ATMIN,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DNAH7,CHST8,AP4E1,BHLHB9,ERCC6L2,PIK3R5,TP53BP2,TRIO,STXBP4,NUTM2A,UGT8,BCL2L13,WRN,ZNF17,ZNF24,KCNT2,ZNF540,LYPD6,ZBTB38,POLR3H,SPIRE1,CADM2,ADAMTS9,SLC17A7,FIP1L1,PARP11,PDSS2,RGS7BP,FZD3,DOCK8,SMIM8,TRAM2-AS1,SNX14,FAM198A" MicroRNA hsa-miR-182:mirSVR_lowEffct hsa-miR-182:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-101 6.86E-98 2.25E-100 2.07E-99 299 1945 "KCNH8,CLK4,KDM5D,ADD1,BRAP,PLEKHH1,USP31,PWWP2A,KIAA1211,BEND6,OLMALINC,KLHL13,HACE1,KIAA1324,OSBPL8,CC2D2A,TAOK1,SEMA6A,PCDH10,GPRASP2,SYT13,AMPD2,AMPD3,LRCH2,ANK2,UPRT,VAT1L,BCAS1,CASK,STK33,SLC4A4,ATP2A2,ATP2B2,DPY19L3,ATP6V1G2,BACH1,MIR9-3HG,MYRF,CALB2,THSD7A,CALM1,PTBP2,CAST,HIP1R,LDB2,USP6,CD86,CDH2,CDO1,CHN2,NRXN3,TPP1,HECTD1,CNGA3,COL4A5,SMARCAL1,TOGARAM2,ENTPD4,CRY2,ANKRD44,GDA,CSNK1E,PDE4DIP,APPL1,PHF14,GREB1,DOCK4,CENPL,GIT2,DNAL1,MYEF2,TIAM2,GUCD1,PLPPR4,WDR20,FAM107B,KIF19,DLX1,GRIN3A,NYAP1,USP3,CPEB2,DPH1,RCAN1,DTNA,MAMLD1,DNM1L,HIPK3,HEYL,SUGP2,APH1A,MRO,KMT5B,RASA4,KCTD3,EIF5,PAN3,EPB41,EPB41L2,COQ7,GPHN,SLC43A2,DNAJC27,SIRPB1,ARMCX1,FAM198B,TAOK3,FER,OLFM1,SPSB4,FGF13,AMOTL2,FHL1,SUCO,FOXO3,EVL,NELFCD,CAMKK2,ATP6V1H,CELF1,ST6GALNAC3,ABLIM2,FYN,GABBR1,GABRB3,ZNF234,LRRC37A6P,KIAA1841,GATM,IGSF5,MMADHC,TNRC6A,ZNF638,RAB40B,GNAO1,FERMT2,GPR34,CNTRL,ADAMTS13,GRM2,PRDM5,FAM107A,GUCY1A1,MUM1,PADI2,ZHX1,FRMD5,BACH2,SYNPO,SMAP1,ZIC5,RBPJ,METTL21A,KCNN2,LAMP2,STMN1,SFXN5,SYTL4,NCOA7,CLEC18A,MARK1,LYPLAL1,MAT2A,MBNL1,CHIC1,KITLG,POC1B,MMP16,MN1,MSR1,N6AMT1,MYO7A,ZC3H12B,NEK1,NOVA1,PCDH9,PDE1C,ENPP2,CCSER2,MAPKAP1,EXOSC10,MAGEL2,EPB41L4B,PPP3CA,CEP41,MAPK7,MAPK10,GRAMD1C,HYDIN,PRODH,GDPD2,MTMR10,PTN,STK32A,PTPRB,ZSCAN2,NKAIN1,RAD17,SH3TC2,ZNF493,RASGRF1,KHDRBS2,MSANTD2,RDX,REV3L,FIGN,RFX3,PRIMA1,RIC8B,CCDC82,CARF,GSTCD,CCDC25,BAALC,MCMBP,ATP8B4,KCNIP3,TRAPPC13,FAM192A,SATB1,LRFN5,SCN7A,SUPT20H,TRA2B,SCAF8,CNKSR2,SYBU,SEC31A,ST8SIA1,PPP4R3A,LIMS2,WDR47,KANSL3,CCDC88A,SLC12A2,ZFP1,CDK5RAP2,MBD5,KIF13A,KDM4B,DOP1A,GLT8D1,PEG10,NFASC,ZNF621,ITPRID2,NXT2,KLHL7,NECAB1,JMJD6,SYNE2,VPS13A,TACC1,AGTPBP1,TCF4,DMXL2,KIAA0930,TCF12,CRTC1,FAM200B,PMS2CL,SIRT1,AKTIP,HEY1,TK2,R3HDM1,TNS1,PIK3R5,TRIO,TRO,PPIL6,TTC3,SGK3,OSBP2,FLRT2,TBC1D15,WIPF1,XPO1,ZBTB14,ZNF23,ZNF24,ZFP41,ZNF74,ZNF189,SH3GLB2,ZFAND5,SMARCAD1,MEIS3,EMSY,PRDM10,VPS35L,PDSS2,DOCK8,MARCH8,HNRNPA3,ACTR3B,SNX14,GAN,CPNE4" MicroRNA hsa-miR-708*:mirSVR_lowEffct hsa-miR-708*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-101 7.32E-98 2.39E-100 2.20E-99 252 1387 "SYN3,ASIC1,ABHD6,ESYT2,SLC24A4,INTS2,TBC1D14,WDR35,TXNDC16,HFM1,C1QTNF3,SMIM17,CEP126,MARCH4,AMPD3,BIN1,PHF12,EPB41L5,MAGEE2,PPP4R4,ZBTB10,NCOA1,NUMB,ATP2A2,ATP2B2,ATP6V1G2,DNAJC27-AS1,BMPR1B,CACNA1G,C5,WASF1,IL33,CACNB4,CALB1,THSD7A,CALM1,PTBP2,ISPD,RUNX1T1,USP6,FOXN3,QKI,PCYT1B,ARMC8,AKAP6,ABI3BP,CLOCK,C2CD2,CREM,AKAP12,GDA,RGS6,IPCEF1,VCAN,CNTNAP2,DZIP3,PITPNM3,APPL1,PUM1,BOC,HDAC9,ARHGAP32,TM9SF4,MATR3,DNAL1,DBN1,SPATA2,YTHDC1,MYEF2,KLHL3,ALKBH8,POM121,PLPPR4,SACS,FAM107B,DMD,NR1D2,DMTF1,CASP8AP2,DNM1L,E2F5,EDN1,EIF4G2,EIF5,TENM1,STARD3NL,VPS13B,NCALD,EXTL2,SH3YL1,ACSL4,ST3GAL6,FKTN,STRADA,GORAB,FECH,FGF1,POLK,SYNCRIP,SLC37A3,ERGIC3,CELF1,MSANTD4,ABLIM2,GABRG1,FAM120B,ERAP1,TUBGCP4,TCERG1,COPS8,GLUL,ZNF638,LNX1,LPAR4,TMEM121B,GRB10,ZNF496,RNF165,SOX21,MAP4K5,HLF,NEGR1,AGFG1,SMAP1,IL6R,ITGA7,ITPKB,KIF2A,KIF5A,LAMA2,LAMP2,STMN1,LIMS1,GPR155,ZFYVE27,CHST6,MID1,PPM1L,SAMD5,MYO5A,MYO9A,MYT1,ZC3H12B,NDP,SFR1,NEK1,NFE2L2,NTRK2,SLC10A4,OLA1,XRN1,FAM216A,PLCL1,PPARA,PPM1B,PPP3CC,PRKCB,DIRAS2,WBP1L,SNRK,CNTLN,PTPRG,ZNF615,TUG1,RAD51D,FAT4,RASGRF2,RADX,ZDHHC14,RET,RGS4,SLC25A36,LGI2,GSTCD,PCMTD2,NEK11,ARMH4,MCMBP,ATAT1,SAFB,CSRNP3,SCP2,GALNT10,COPZ1,BTBD3,SLC14A1,BTBD7,ATF7IP,CPEB4,ARFGAP1,CDK5RAP2,SMARCD3,ANKRD36,MBD5,ZNF415,SNRPN,FAM126B,PDZD2,TRERF1,BDP1,FNBP1,KDM3A,ERC1,CDK19,CLSTN2,SEPT8,KLHL7,COBL,TACR1,FAM208A,ADGRL3,SMG6,DMXL2,CLASP1,SYNE1,PCDHB9,PCDHAC2,PCDHA7,CRTC1,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,ITGB3BP,AP4E1,ARL10,TIAM1,HEY1,TMPO,RIMBP2,NR2C2,PDSS1,TRPS1,FAM155A,PLEKHH2,BCL2L13,GUSBP1,XPO1,LYPD6,REEP1,ZFAND5,EVI5,ADAMTS9,FIP1L1,RGS7BP,ST7,KAT6A,SNX14,FXR1" MicroRNA hsa-miR-888:mirSVR_highEffct hsa-miR-888:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.31E-101 7.33E-98 2.39E-100 2.20E-99 271 1605 "CLK4,NCKAP5,CCDC85A,ADRB2,BEND6,INTS2,ALCAM,ARHGAP20,GPRASP2,CDC42BPA,DPP10,LRCH2,ARRB1,MARCH3,NUMB,SLC4A4,ATP1B3,RNF182,N4BP2L1,BARD1,ZNF599,SYNJ1,SCAPER,CACNA1B,KALRN,CLDN10,KRIT1,LRBA,MAGI1,RCBTB2,SRSF11,DGCR9,QKI,CNGA3,COL4A5,SLC4A8,ZNF521,PREPL,C2CD2,ENTPD4,HAPLN1,ANKRD44,NCOR1,LRRC3B,SOCS5,PDE4DIP,SLITRK5,DCAF4,USP6NL,CCDC144A,HDAC9,GPRASP1,ARHGAP32,TBC1D5,DGKB,FBXL5,PLPPR4,SPOCK3,WDR20,FAM107B,NR1D2,DMTF1,DNAJB6,DNM1L,E2F5,E2F6,WDPCP,FCF1,SEMA3D,KLHL5,YAF2,PHF20L1,APH1A,MBNL2,KMT5B,PLEKHA1,VPS13B,SRRM1,DENND4A,SIRPB1,ADGRV1,DLC1,CEP78,GORAB,FGF14,IP6K2,SLC37A3,AFF2,FOLH1,JKAMP,STAMBP,ATP2C1,STAU2,FYB1,HRASLS5,TRAF3IP2,ERAP1,MTHFD2,LRRC37A6P,ARFIP1,PPARGC1A,RNPS1,GPR75,TOX3,TNRC6A,DCLK2,GPD2,LILRA2,GPR12,GPR37,GRB10,GRIA2,GRIN2C,MAP4K5,PACSIN2,HLF,ELOVL5,GABARAPL2,CELF5,ZNF546,ZIC5,RBPJ,KNDC1,NME9,METTL21A,KCND2,KLHL23,STXBP5,STMN1,HECTD2,GPR155,MAP2,AQP11,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,ADAM22,ZNF92,MXI1,MYCN,NDP,NEFM,NEK1,NF1,NFE2L2,CNOT4,NUCB2,OCRL,CLDN11,GPR137C,CDK18,PDE4D,GNG2,PFKFB2,SNX10,RETREG1,XRN1,SMIM7,TRHDE,MAPKAP1,EXOSC10,EPB41L4B,PRKACB,DIRAS2,SNRK,ANKHD1,ELOVL2,TMEM260,PTPRN2,PTPRO,TMEM231,ACSS3,CCDC40,FAT4,RADX,KHDRBS2,MSANTD2,REV3L,RGS3,RGS4,SLC25A36,ZNF532,SETD5,EXD2,CCDC25,ELP2,PCMTD2,RPE,RPL15,FBXW7,KCNIP1,RTN1,NCBP3,SCN8A,FNIP1,GALNT10,SUPT20H,HSPA4L,CHD9,FHOD3,SYBU,EPN2,BTBD7,SLC22A4,CPEB4,ZNF667,ANKRD36,MBD5,CABCOCO1,USP33,NMNAT2,SPP1,KDM4C,MCF2L2,RBM26,SPART,LMO3,CLASP2,TROVE2,SSTR1,ZC4H2,SS18,ERBIN,PRRC2C,PLCB1,SYPL1,SYT1,MTCL1,CAMTA1,ADGRL3,TBCEL,DMXL2,SATB2,CLASP1,SYNE1,SIK3,TK2,TMPO,KAT6B,C9orf85,RGMB,SYNPO2,RUNDC3B,AMACR,DCBLD1,FAM155A,UBE3A,ZNF709,BCL2L13,ZNF711,ZNF19,KCNT2,ELFN1,LYPD6,ZBTB38,ZNF189,UPF3A,EMSY,PRDM8,PRDM10,RNF103,HPS4,WNK3,PLSCR4,FAM13C,FZD3,DOCK8,JMJD1C,IFT88" MicroRNA hsa-miR-449b*:mirSVR_lowEffct hsa-miR-449b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-101 7.45E-98 2.42E-100 2.23E-99 287 1797 "VWA5B2,RALGAPA1,ADD1,ADD2,USP31,DPY19L2P4,MTUS1,OSBPL1A,KIAA1324,TAOK1,C1QTNF3,SMIM17,SYT13,ZNF687,AMPD2,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,APBA2,FAM131A,PHYHD1,PPFIA3,USP37,IGDCC4,ARNTL,LINC00173,MARCH3,ZSCAN18,STX16,DPY19L3,ADAM15,BCL7A,KSR1,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,GPC2,WASF1,CH25H,CBR1,ZNF501,USP6,ENTPD6,LOC730101,TIGD7,CCPG1,CHN2,TAOK2,NRXN3,CLCN3,C4orf33,SULT4A1,IGLON5,ARHGEF6,CNR1,PCYT1B,ZNF521,SLC35F1,CREM,CRY2,ANKRD44,GDA,TRIM69,SNCAIP,CSF1R,SOCS5,CNTNAP2,APPL1,ARHGEF4,MYADM,HDAC4,KIAA0586,DGKG,IP6K1,ZBTB24,RUSC2,SNAP91,SV2B,SGSM2,WDR20,CHRDL1,DLX1,EXOG,GRIN3A,USP3,CPEB2,DRP2,DTNA,EDNRA,EDNRB,RASGRP1,YAF2,EIF5,EPB41,STX2,VPS26C,ANKMY1,EZH1,FDFT1,ZNF589,FGF1,AMOTL2,PRKAG2,POLK,SYNCRIP,PSD2,PDLIM5,SARAF,HHIPL1,ABLIM2,OGA,GABBR1,GALNT15,GAD1,FAM120B,B4GALNT1,ERAP1,SIGLEC8,GATM,TUBGCP4,GFER,CSDC2,DCLK2,GPD2,CCDC184,ADAP1,GPER1,PCLO,GRIA2,PLCD4,SPACA9,ADAMTS13,ATE1,ZNF496,BTN2A1,RNFT2,EID2B,IRF8,IDH3A,IDH3B,TJAP1,SCIN,SLC6A17,ITGA7,KCNJ5,KCNK3,A1BG-AS1,IPO5,STXBP5,STMN1,MAP2,CHIC1,MEIS1,SRSF12,KITLG,AFDN,MMP16,GIT1,N6AMT1,NEK1,NFYA,NPTX1,SMIM11A,NTRK2,NTRK3,NUCB2,OPA1,ZNF713,CDK18,PDE3A,PDE4D,PFKFB2,ZNF655,CCSER2,PLCL1,PLIN1,PDZRN4,POU6F1,PPP3CA,WBP1L,ANKHD1,BDNF-AS,ZIK1,PTPRD,PTPRO,USP47,SH3TC2,OXR1,ZDHHC14,GTDC1,NUDT11,ARMC5,GSTCD,CYB561D1,KIRREL1,ROBO2,SNX22,NEK11,EPHA10,BAALC,MCMBP,GLDN,EMID1,HUNK,RTN1,SCP2,SEC14L1,CASC3,SLC2A5,SIRT2,SLC12A2,BTBD7,IFT122,MBD5,TMCC1,DOP1A,ZSWIM8,SP4,GLT8D1,HECW1,RBM26,SPART,TROVE2,ZC4H2,LARP4,ZSCAN29,SEPT8,CEP68,SEPT3,SUPT5H,PRRC2C,ANKRD12,ATMIN,KIAA0930,TPCN2,DOCK9,PHF24,PCDHB3,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CYB561A3,FAM200B,ZFPM2,GPR161,ACTR6,PRRT1,RGMB,NR2C2,TRO,STXBP4,RUSC1,ZKSCAN5,ZNF610,CCDC14,VLDLR,WIPF1,XPO1,ZNF24,KCNT2,TRIM9,REEP1,SPIRE1,MEIS3,SLC30A3,MAP3K12,GDPD5,HPS4,VPS35L,GAL3ST3,FAM47E,PDSS2,EPM2A,DOCK8,FBXO36,NHSL1,SOCS4,GAN,ZNF30" MicroRNA hsa-miR-561:PITA hsa-miR-561:PITA_TOP PITA 1.64E-101 9.19E-98 2.97E-100 2.74E-99 212 968 "XKR4,CCDC85A,PWWP2A,HECW2,ALCAM,FAM135A,LRFN1,APC,EPB41L5,USP37,CDC14B,PPP4R4,CASK,ZSCAN18,TMEM108,SLC4A4,STX16,DPY19L3,ADGRB3,SYNJ1,ST3GAL5,MTMR2,WASF1,CA8,CAMK2A,CAST,SPAG9,CBLN1,LDB2,CCNH,AP4M1,SEPT7,ZMYM4,CACNA2D2,FOXN3,SOCS6,QKI,HECTD1,CNTN1,ZNF521,CRHBP,HAPLN1,LRRC3B,CSNK1G3,SOCS5,PPP1R16B,RIMS2,LONRF1,IST1,SPOCK2,PITPNC1,MYEF2,MFAP3L,RHOBTB1,SNAP91,SACS,DLX1,NR1D2,CPEB2,PDCD6IP,MAMLD1,GOLT1B,CELSR3,MBNL2,GOLGA7,TMEM35A,PAN3,EIF1,EMX2,RCAN2,RRAGB,TAOK3,SCML2,FECH,MED12L,ANKFY1,NBEA,FAM49B,KHDRBS3,CSPG5,MSANTD4,MEGF10,GABRB3,ERAP1,GATM,GHR,TCERG1,FERMT2,GPD2,GRB10,GRIA2,CIT,RNF165,LINGO1,ADAMTS6,ZHX1,MIER3,HLF,ELOVL5,HNF4G,CFAP126,IGF1,NKD1,RBPJ,LRRTM1,KCND2,KCNN2,STXBP5,LIFR,SMAD1,MATN3,MBP,CHIC1,LRP1B,MEST,KITLG,MITF,AFDN,MN1,MYCN,MYH3,MYO5A,NEXMIF,ZC3H12B,NF1,NFE2L2,PDE3A,CCSER2,FAM216A,PURG,STRN3,PPP2R2B,LRRN3,PPP3CA,PRKAB2,PKIA,QRICH1,PTCH1,PTPRD,USP47,RBBP6,KHDRBS2,RGS4,RIC8B,ZFHX4,LGI2,CARF,ROBO1,ROBO2,FBXW7,MCMBP,ATP8B4,KCNIP3,ZNF331,RMI1,ATXN2,SMPD3,SCAF8,CPEB3,FNDC3A,CCDC92,WDR37,PPP4R3A,WDR47,CCDC88A,KBTBD4,SLC12A2,CPEB4,RCOR3,SNAP25,FAM126B,FNBP1,SOX11,ZHX3,SP4,CDK19,POGZ,STAU1,TTBK2,RGL1,NECAB1,PRRC2C,SYPL1,ANKRD28,ANKRD12,CAMTA1,ADGRL3,SATB2,TRIM2,FRYL,SIRT1,ZFPM2,ITGB3BP,SLC44A1,TIAM1,NR2E1,ERCC6L2,TP53BP2,PDSS1,TRPS1,TSC1,UCHL1,VLDLR,LYPD6,CELF4,ZFAND5,PRDM8,HNRNPA3,PHTF2,ADAMTSL3,FXR1,NETO2" MicroRNA hsa-miR-1909:mirSVR_lowEffct hsa-miR-1909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-101 1.10E-97 3.55E-100 3.27E-99 296 1911 "VWA5B2,ASIC1,ACHE,SYS1,GALNT16,RNF157,PLEKHH1,AP2A2,PCDH19,KCTD16,CARNS1,GPRASP2,PDZD4,AMPD2,SEMA7A,FGD2,PHF12,SUGT1P4-STRA6LP-CCDC180,LGR5,AQP6,SEMA4G,MADD,ARHGDIG,CCAR2,TMEM108,ATP1A3,MPDZ,MIR9-3HG,CFLAR,LDHD,KSR1,SYNJ2,CACNA1I,WASF1,BAIAP3,CACNA2D1,LURAP1,CALB2,KALRN,HAP1,CAMK2G,CBLN1,KYAT1,ARHGEF2,KCNAB3,LRRFIP1,NOG,CRLF1,SRSF11,PLEKHB1,CHRNA4,TAOK2,EPS15L1,NRXN3,IGLON5,ARMC8,TOGARAM2,ZNF385A,RBM39,GDA,TRIM69,CSF1,SEC24C,LRIG1,PITPNM3,PNPLA8,PUM1,RUBCN,GAPVD1,EARS2,PITPNC1,DCTN1,B3GAT3,MFAP3L,PARD6A,WDR20,CD99L2,SLC29A4,ARRDC4,DTNB,FIS1,EDN1,FCF1,TMTC1,CELSR3,PHF20L1,EGFR,TMEM132E,RASA4,EIF4G1,MRNIP,EIF1,EPB41L2,EPHB1,ENPP6,SLC43A2,CEP85L,SPEG,MRPL10,PIPOX,ANKMY1,SIRPB1,F5,TAOK3,RACK1,FCGR1B,KAT8,PPP1R1B,POLR1B,FGF11,SPSB4,EVL,NOP56,SYT3,AK8,PDLIM5,GABBR1,HRASLS5,GALNT15,B4GALNT1,GHDC,SIGLEC8,C15orf41,LRRC37A6P,TUBGCP4,SRCAP,CYP46A1,AHDC1,USP19,MALT1,RUNDC3A,GLYR1,STARD3,KDM2B,KCNMB4,GNAO1,LILRB4,PRUNE2,MCHR1,GRB10,LINC01089,GSN,KAT7,LINGO1,GUCY1B1,SLC2A6,UBE2QL1,MAN1B1,DDX19B,ATXN2L,HMGCL,HNF4G,FAM95B1,MYLK2,IGF1,RBPJ,TJAP1,IL6R,C2CD4C,GPR62,KCNK3,LINC00634,A1BG-AS1,STXBP5,TTYH2,CAMK2N2,PAXBP1,LSS,MAP4,MARK3,SCAMP5,MOV10,MPP2,GIT1,MSI1,NRBP2,MYO7A,RTL5,BEX5,FXYD7,P2RY13,DNHD1,SMIM11A,NTRK3,ZNF827,CDK18,PDE4A,KCTD15,PLEC,MTRF1L,EXOSC10,FA2H,POLR2F,VSTM2L,PRKAR1B,MASP1,NDUFS7,BCAS3,ELOVL2,SLC25A48,FAT4,KCTD17,RNASEL,ELP2,MRAP2,SGSM1,ADAL,MAP6D1,ATAT1,STX1B,FAM192A,DGLUCY,MAPK12,SARS,SCP2,SEC14L1,CASC3,KIF21A,ARX,R3HDM2,PPP4R3A,KANSL3,SLC6A8,BTBD7,LGI3,ARFGAP1,SMARCD3,MYH15,RCOR3,KIF13A,KDM4B,SP2,ZSWIM8,DBNDD2,LHPP,SSTR1,SEPT8,STAC2,ADHFE1,PHLDB1,STXBP1,RHBDL3,ARC,SYP,TACR1,CAMTA1,MCF2L,EXOC7,PDLIM2,NEU4,TPCN2,RPGRIP1L,SZT2,DOCK9,SIK3,RNF216P1,MTMR14,TIMP4,RELL2,RIMBP2,TP53BP1,NPL,STXBP4,TRPM2,PPIL6,RUSC1,KCNE5,HIRA,CLEC2L,UBTF,OSBP2,FLRT2,MGAT5B,PLPPR2,VSNL1,LAT2,GUSBP1,XRCC4,PCDH20,ZNF70,DPYSL5,PCBP1-AS1,MAP3K12,EVI5,GDPD5,CIAPIN1,ITM2C,RGS7BP,UBE3B,TMEM63C,TRAM2-AS1,TIGD6,TTC7A,LAS1L,SPATA13,JPH3" MicroRNA hsa-miR-190:mirSVR_lowEffct hsa-miR-190:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-101 1.31E-97 4.20E-100 3.87E-99 278 1692 "ACADM,CLK4,ACTN1,NDRG3,CCDC85A,PLEKHH1,PWWP2A,HECW2,RTL9,HACE1,KIAA1324,WDR35,SPARCL1,PCDH10,BBOX1,SEMA7A,MAP4K3,LGR5,MARCH3,ASPA,TMEM108,ZNF582,DPY19L3,BBS2,BCHE,MIR9-3HG,KSR1,FUBP1,C5,RAB29,LDLRAD4,CACNB4,KALRN,CAST,ISPD,CCNH,RGN,MTMR7,P2RX6,LRBA,DCLK1,NUMBL,SRSF11,CHGB,SOCS6,CHN1,B4GALT6,RAB33A,MAP4K4,CNTN1,AKAP7,IQCK,COL4A5,BAG4,SNCAIP,RGS6,CNTNAP2,FAM169A,UBXN2A,CTH,PUM1,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,LONRF1,MATR3,KCTD8,DGKB,DAPK1,ARMCX4,ARMCX2,ELMSAN1,JAKMIP2,HEPH,KIAA0319,PLPPR4,SACS,MTX3,NR1D2,DOCK2,DUSP9,DNM1L,GOLT1B,KLHL5,MBNL2,KMT5B,EGR3,TENM1,PCOLCE2,STARD3NL,C8orf37,EIF1,VPS13B,EPB41,LRRC17,RABEPK,DENND4A,ADGRV1,EYA1,TUBA1B,GTF2IRD2,FGF13,SCARA3,IP6K2,RGPD5,FOXO3,SLC37A3,NOP56,SMC2,PDLIM5,STAMBP,ERGIC3,NSG1,MPP6,MEGF11,HRASLS5,GABRB3,ERAP1,ZNF559,DISC1,LRRC37A6P,MMADHC,TCERG1,COPS8,HPGDS,FUT10,STMN2,RNF165,GUCY1A1,RASSF8,BACH2,HLF,SYNPO,LRRC75A,FAM69A,KCND2,KIF2A,KIF5A,KIT,A1BG-AS1,MAN2A2,MAT2A,TM6SF1,MEF2C,MGAT3,KITLG,PPM1L,SAMD5,NRBP2,HS6ST3,LAYN,MYO5A,CNOT4,SLC11A2,NTRK2,SETD4,LOC100128398,DPY19L2P2,PCSK1,PDE4D,ENPP2,ZDHHC8,SNX10,RETREG1,XRN1,MTRF1L,PURG,PMP22,LRP12,EXOSC10,SDK2,KANSL1,PRKCB,MAPK4,CNTLN,MTMR10,PTPRB,PTPRE,PTX3,ZSCAN2,TUG1,CEP97,ZCWPW1,RASGRF2,RBBP6,HKR1,DPF2,RGS12,CCDC82,ROBO1,ROBO2,SGSM1,LRRK2,AP1AR,SEMA6D,CSRNP3,SCN2B,SCP2,MRAS,SCAF8,SGK1,CPEB3,CHD9,ST6GAL1,SEC31A,FAM81A,SLC8A1,NAPB,SLC22A4,CPEB4,MAST1,ANKRD36,FAM126B,BDP1,ZHX3,UHRF1BP1L,CLASP2,ITPRID2,SAMSN1,SSTR1,ELOVL4,DIP2A,PRRC2C,VPS13A,NUDT10,SYPL1,SYT1,COBL,TACR1,PJA1,FAM208A,ADGRL3,KIAA1107,TBL1X,ATMIN,TCEA1,TCF4,DMXL2,ZEB1,TRIM2,SYNE1,TNS2,DICER1,ZFPM2,C18orf54,KAT6B,TP53BP2,TPM1,NPL,TRIO,TRPS1,ZNF610,FAM155A,EIF4ENIF1,BCL2L13,CCDC14,VSNL1,XPO1,XRCC4,PCDH20,KCNT2,NDRG4,SMARCAD1,DHX33,CADM2,SLC38A1,EVI5,PRDM8,MPPE1,RTN4,JMJD1C,KLHDC1,FXR1,NETO1,SOCS4" MicroRNA hsa-miR-632:mirSVR_lowEffct hsa-miR-632:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-101 1.71E-97 5.48E-100 5.05E-99 275 1658 "ABR,SYN3,ACTN1,KIAA1211,MTA3,PCDH19,CC2D2A,CEP126,ABCD2,CARNS1,SUGT1P4-STRA6LP-CCDC180,FAM131A,LGR5,CDC14B,ARNTL,ARRB1,NUMB,EIF4G3,SLC2A11,RIPK1,BACH1,SYNJ2,ARHGEF7,FUBP1,CACNA1I,CACNA1A,CACNA2D1,CALB2,CABP7,ISPD,RUNX1T1,P2RX6,SCARB1,LRRFIP1,CLGN,CACNA2D2,CHN2,PLEKHB1,EPS15L1,TPP1,DGCR9,QKI,MAP4K4,FAM149A,WHRN,SUMF2,LETMD1,SMARCAL1,TOGARAM2,CPS1,PREPL,C2CD2,GDA,ARHGEF10,DZIP3,UBXN2A,PHF14,GPSM1,DOCK4,ARHGAP32,KATNAL2,SNPH,ARHGAP24,EARS2,ZNF337,LIN54,DGKB,DAPK1,GIT2,YTHDC1,GSDME,SPOCK3,SGSM2,HS3ST2,RPS6KL1,DMTF1,PDCD6IP,DUSP9,GOLT1B,E2F6,EDNRB,SEMA3D,MBNL2,EGR3,EIF5,ELN,ENPP6,SPEG,F8,CLVS1,FCGR1A,CHST15,ZNF589,FGFR1,PRKAG2,MEX3B,SEMA4D,PSD2,PDLIM5,STAU2,ABLIM2,MEGF10,GABRB3,IP6K3,DISC1,CPLX1,ALDH1L1,MALT1,AIFM3,WDFY3-AS2,LILRB4,GPD2,GPR12,PCLO,GRIA2,PLCD4,ADAMTS13,GSN,ZBTB49,FAM107A,ADAMTS6,PADI2,PACSIN2,MAN1B1,ATXN2L,AGBL5,ZNF491,CELF5,FAM95B1,C2orf72,GAREM2,LRRCC1,FAM69A,INSM1,ITPKB,KCNK3,L1CAM,LAMP2,HECTD2,NCOA7,GPR155,MAN2A2,ZFYVE27,MEIS1,MEIS2,MID1,PPM1L,XRRA1,DBNL,ADAM22,LAYN,RTL5,ZNF862,NF1,ALDH1L2,CHAMP1,DPY19L2P2,GPR173,NLGN3,TMIE,PIK3R1,ANKRD16,PRKAB2,PRKACB,PRKCB,MAPK9,QRICH1,BDNF-AS,MTMR10,ELOVL2,PTN,ZIK1,PTPRD,ZNF844,CEP97,SLC25A48,ACSS3,OXR1,ZDHHC14,RET,RGS4,SLC25A36,RIC8B,PBRM1,RNASEL,RNH1,LGI2,ARMC5,CCDC102B,FBXW7,BAALC,SPIN3,ATP8B4,S100B,DGLUCY,SEMA6D,SCN2B,SCN8A,FNIP1,FOXRED1,SH3GL3,FERMT1,MYO18A,ST6GAL1,WDR47,SLC8A1,SLC12A4,SLC14A1,NAPB,EPC1,SMARCD3,LIMCH1,MBD5,SNRPN,KDM4B,BDP1,KDM3A,HECW1,SPP1,KDM4C,IQSEC2,MCF2L2,RBM26,ITPRID2,MESP1,ZC4H2,NKAIN2,STAC2,ADHFE1,SULF2,NECAB1,JMJD6,ADAMTS17,TAF6,TBCEL,TBL1X,PHF24,USP32P1,TIAM1,TMEM9,BHLHB9,LRRC8A,TMPO,C9orf85,ELP5,TRIO,PPIL6,SSBP2,CLHC1,RPL7L1,UCHL1,MGAT5B,MTCH1,CLIP2,LAT2,ZIC1,ZBTB38,ZNF177,ZFAND5,DNALI1,CIAPIN1,GAL3ST3,NAV3,PCBP4,PLSCR4,PARP11,HRASLS,FBXO36,FAM219B,JMJD1C,RNF170,FRMD6,IFT88,NETO1,GAN" MicroRNA hsa-miR-374b*:mirSVR_lowEffct hsa-miR-374b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.42E-101 1.91E-97 6.12E-100 5.63E-99 288 1816 "SYS1,NDRG2,TMEM132B,TMCC3,GALNT13,PLEKHH1,PWWP2A,KIAA1211,PTCHD1,ADRB2,HACE1,OSBPL1A,KIAA1324,WDR35,TXNDC16,CC2D2A,HFM1,SMIM17,SPOP,ALCAM,CEP126,ABCD2,FAM135A,PARG,APAF1,APBB2,UPRT,BCAS1,PPFIA3,CDC14B,PPP4R4,TMEM108,ATP2A2,ATP2B2,ADAM15,PROM1,FUBP1,IL33,CA4,LURAP1,RUNX1T1,CD86,C1orf52,CDH2,NOG,NUMBL,DIS3L,NDST3,RAB28,LY86,RAB26,FHL5,CNN3,SLC35F1,PREPL,HAPLN1,HINFP,SUSD5,USP6NL,KIAA0408,BOC,RIPOR2,MATR3,DGKB,DAPK1,IP6K1,BRINP1,DNAL1,SPATA2,KIAA0753,SNAP91,SACS,SPOCK3,NR1D2,DPYSL2,ACOT8,PDCD6IP,DNAJB6,ABCC5,WDPCP,PHC2,ANKRD46,HIPK3,FEM1B,CNNM1,SEMA3D,MBNL2,AASS,ASB3,ELN,TMEM35A,EIF1,EPHB1,RABEPK,SRRM1,KATNAL1,ADGRV1,EZH1,ABCA8,ZNF461,RPS6KC1,TMEM132C,ACSL4,SCML2,SEC24B,FGF13,HPCAL4,SEC23B,SYNCRIP,TMEM107,FAM49B,CAMKK2,ATP6V1H,ST6GALNAC3,SARAF,OGA,GALNT15,IQGAP2,LRRC37A6P,GATM,ADAM28,CRCP,TCERG1,COPS8,KCNMB4,GPR37,PCLO,STMN2,GRM8,BVES,PSIP1,GUCY1B1,IRAK3,RASSF8,LRRC75A,CELF5,SOWAHA,IL12A,INPP5B,KCNH2,CREG2,STXBP5,KTN1,LAMP2,PAXBP1,SYTL4,SMAD1,MARK1,AQP11,EFHB,MEIS1,KITLG,AFF1,COL28A1,SAMD5,MYO9A,NF1,NFYA,NINJ2,DNHD1,NTRK2,NTRK3,OPA1,CNTN3,PRTG,PDE4D,PFKFB3,PFKFB4,ZDHHC8,ZNF655,KCTD15,FAM216A,STRN3,EPB41L4B,LRRN3,PRKCB,MAPK9,RELN,LAMA1,BDNF-AS,CEP97,ENOX1,REV3L,FIGN,RFX3,ZFHX4,CCDC82,CARF,CCDC25,YY1AP1,CCDC102B,NEK11,EPHA10,ATP8B4,RTN1,ZNF331,SEMA6D,SCP2,TNFRSF19,SGK1,SH3GL3,PPM1E,ARX,CPEB3,CNKSR2,NLGN1,SEC31A,NUBPL,EPN2,KDM4D,BTBD7,CDK5RAP2,RCOR3,INAVA,MBD5,TMCC1,TRERF1,TSNAXIP1,SP2,UNC5B,CDK19,TSPYL2,RBM26,ZNF621,SSTR2,ZC4H2,ADHFE1,KLHL7,RHBDL3,SYP,SYT1,C12orf76,TACC1,TACR1,TAF9,FBXW11,KLHL4,ATMIN,DMXL2,SATB2,ZEB1,RPGRIP1L,CLASP1,SZT2,SYNE1,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,ITGB3BP,AKTIP,SLC44A1,NACC2,TMPO,ANKRD20A2,TTTY15,ZKSCAN5,HIRA,EIF4ENIF1,UBE2H,UBE3A,GORASP1,ZNF709,BCL2L13,VGF,XRCC4,ZIC1,ZIC2,AGMO,ZNF154,TMEM237,ANKS1B,UPF3A,RNF103,URM1,PDSS2,RTN4,FBXO36,TIGD6,NHSL1,NETO2,GAN,SENP7" MicroRNA hsa-miR-653:mirSVR_lowEffct hsa-miR-653:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.66E-101 2.61E-97 8.30E-100 7.64E-99 293 1880 "ACADM,NCKAP5,XKR4,NDRG3,CCDC85A,KLHL13,CASKIN1,PCDH19,HACE1,OSBPL6,AK2,SPARCL1,ALCAM,GPRASP2,SYT13,BEGAIN,TRMT9B,AMPH,CCDC146,APBB2,USP37,PPP4R4,RGS20,ZBTB10,CCAR2,TMEM108,SLC4A4,ATP1B3,ATP2B2,ADAM23,ADGRB1,ADGRB3,KSR1,LDLRAD4,KALRN,PTBP2,RUNX1T1,PRC1,CBR1,ENTPD6,C1orf52,DCLK1,B4GALT6,NRXN3,CLTC,FAM19A5,QKI,CNN3,CNTN1,AKAP6,WHRN,AKAP5,RCHY1,SMARCAL1,RTTN,MYRIP,FAM171B,CDC42BPB,SH2B1,ANKRD44,NCOR2,GDA,CSNK1E,CSNK1G3,IPCEF1,SIPA1L1,UBXN2A,PHF14,PUM1,ZSCAN23,SEC14L5,ARHGAP24,ZNF337,MATR3,KIAA0586,DGKB,DGKG,TMEM170A,DBI,GIT2,DNAL1,ARMCX4,ARMCX2,KLHL3,DDX46,POM121,SACS,MTX3,USP3,DMTF1,DTNA,DNM1L,GOLT1B,E2F5,TMTC1,KMT5B,TENM1,EPB41,GPHN,ERBB4,DNAJC27,EZH1,NRN1,F5,RPS6KC1,TBC1D16,SPSB4,FGF13,SCARA3,FOXF2,AGAP2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,NELFCD,UFM1,ST6GALNAC3,CSPG5,AP4B1,CHL1,GABRG1,GCNT2,TUBGCP4,MSTN,ARFIP1,CYP46A1,MALT1,COPS8,RAB30,TNRC6A,ZNF638,KCNMB4,RAB40B,PCLO,STMN2,SERP2,FAM19A2,COQ10A,KAT7,RABL2A,LINGO1,RNFT2,GUCY1B1,MAP4K5,RASSF8,HAS2,MAN1B1,INSYN1,AGBL5,HSF2,EID2B,SCIN,IL6R,INPP1,INPP5B,INSM1,KCNN2,KTN1,SYTL4,HECTD2,GPR155,MAT2A,CHIC1,MEIS2,PPM1L,AFDN,XRRA1,ADAM22,TAGLN3,MYO6,MYO7A,ZC3H12B,NTRK2,NUCB2,IGSF11,PAX6,PCDH9,PDE4D,SLC10A4,OLA1,PIK3C2A,PIK3R1,ZNF655,PRIMPOL,MAGEL2,EPB41L4B,DRAM2,RASGEF1B,ANKHD1,MTMR10,PTN,PTPRE,TTC13,ZNF615,RDX,GAL3ST4,ERI2,GTDC1,FIGN,RGS3,RIC8B,ZFHX4,GSTCD,ARMH4,BAALC,SATB1,LRFN5,SCP2,SEC14L1,FERMT1,HKDC1,FNDC3A,DZIP1,ABLIM3,WDR47,SLC6A8,ZNF430,SEPHS1,SLC8A1,BTBD7,CPEB4,GKAP1,SMARCA4,TTC17,MYO16,KDM4B,FAM219A,DOP1A,TRERF1,BDP1,SP4,NMNAT2,GLT8D1,KDM4C,PEG10,ZBTB43,NFASC,ZNF621,CLSTN2,POGZ,ITPRID2,ZNF302,LARP4,CEP68,SEPT3,NECAB1,DNAJC9,SYT1,TACC1,PJA1,MCF2L,FAM208A,TCF4,DMXL2,SATB2,ZFP90,DOCK9,GPRIN3,AKTIP,SLC44A1,RIMBP2,TPM1,NPL,TRIO,AMACR,UBC,EIF4ENIF1,UCHL1,GORASP1,FLRT2,USP1,TBC1D15,WNT7A,CLDND1,GUSBP1,ZIC1,ZNF708,KCNT2,ZNF540,ANKS1B,SPIRE1,UPF3A,INTS3,FIP1L1,FAM47E,RGS7BP,FAM13C,AMN1,KAT6A,HNRNPA3,NLRP3,MSRB3" MicroRNA hsa-miR-581:mirSVR_lowEffct hsa-miR-581:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.83E-101 2.70E-97 8.58E-100 7.90E-99 277 1685 "ABHD6,NCKAP5,PTCHD1,KCTD16,C1QTNF3,ALCAM,PCDH10,AMPD3,MAGEE2,PHYHD1,BCAS1,CDK13,NUMB,INSYN2B,CHID1,STX16,RNF182,N4BP2L1,DPY19L3,ADAM23,LINC00847,CFLAR,ST3GAL5,FUBP1,SGCE,LDLRAD4,CACNA1A,CACNA1B,KALRN,RUNX1T1,CBFA2T2,SEPT7,ZBED1,CCPG1,CHGB,TAOK2,LHX2,RAB33A,CLCN3,ABCG2,AKAP6,TRIM69,SNCAIP,RGS6,CST3,PPP6R2,ZSCAN23,DCAF4,FAM131B,CCDC144A,BOC,KIF26A,LONRF1,TM9SF4,DGKG,TMEM170A,GIT2,JAKMIP2,KIAA0753,KLHL3,ZC3H11A,GSDME,DDX46,SPOCK3,ZNF582-AS1,DLX1,RAB39B,USP3,DMTF1,ACOT8,DTNA,DUSP9,DNM1L,SEMA3D,FRY,EIF4G2,EIF5,TENM1,C3orf18,TMEM35A,VPS13B,RAB9B,IGSF6,TLR7,RRAGB,F8,ACSL4,PTK2B,DLC1,FKTN,STRADA,GORAB,SEC24B,MED12L,FGF12,FGFR1,SUCO,UBE2E3,SYNCRIP,FOXO3,PSD2,NOP56,C2orf88,SPECC1,FAM49B,ATP2C1,KHDRBS3,ST6GALNAC3,FYB1,HRASLS5,IQGAP2,ERAP1,TMEM8B,TUBGCP4,ARFIP1,CYP46A1,ADAM28,GFER,MALT1,SPIN1,ZNF638,CBX1,KIAA1958,DCLK2,GNAO1,STON1,LPAR4,PCLO,GRIA2,DIDO1,CIT,BTN2A1,AP4S1,RABL2A,RASSF8,PADI2,MAN1B1,MIER3,HLF,AGFG1,LRRC75A,SMAP1,IGF1,SLC6A17,LRRTM1,ITPKB,SLC35G1,KCND2,CYP27C1,STMN1,ZFYVE27,MARK1,MARK3,LRP1B,MEIS2,KITLG,MID1,AFF1,AFDN,XRRA1,ZNF680,ADAM22,PTOV1,NDP,NFE2L2,ALDH1L2,PCBP3,NTRK2,OXTR,CNTN3,DPY19L2P2,PDE1C,GPR173,PIK3R1,PLIN1,PSAT1,SDK2,SEPT4,MINDY2,RASGEF1B,CEP41,BCAS3,NCR3LG1,BDNF-AS,ELOVL2,PTN,EML5,TMEM231,SH3TC2,DPF2,REV3L,ERI2,FIGN,RFX2,SETD5,ROBO2,SNX22,NEK11,BAALC,ZC3H14,SGSM1,PTGR2,MEG3,RTN1,SATB1,SCP2,GALNT10,FHOD3,DHX30,KANSL3,TRIM67,BTBD7,ZFP1,GKAP1,ANKRD36,MBD5,ZNF415,BDP1,UNC5B,PEG10,SPART,PBLD,STAU1,ELOVL4,NEK4,SUPT5H,PLCB1,ANKRD28,SLC37A2,MTCL1,WSCD1,SATB2,ZEB1,TRIM2,TCF12,SYNE1,PHF24,SLC19A3,USP32P1,TNS2,PMS2CL,DICER1,SIRT1,ITGB3BP,MTMR14,TK2,TLR4,NR2E1,LRRC8A,TP53BP2,PDSS1,FLRT2,ZNF709,VSNL1,WIPF1,KLC2,RICTOR,GUSBP1,MICU3,EML6,DPYSL5,ZNF213,EMSY,PRDM8,NAV3,FAM47E,WNK2,PLSCR4,PARP11,FAM13C,KAT6A,FBXO36,ADAMTSL3,TIGD6,SNX14,NETO1,ST8SIA2" MicroRNA hsa-miR-590-5p:mirSVR_highEffct hsa-miR-590-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.47E-101 3.06E-97 9.68E-100 8.92E-99 242 1285 "RALGAPA1,CCDC85A,ESYT2,PTCHD1,DPY19L2P4,ZNF608,CASKIN1,PCDH19,OSBPL8,ADGRF5,ARHGAP20,AMPD3,OGT,DPP10,LCORL,APAF1,USP37,N4BP2L1,BCL7A,ARHGEF7,FUBP1,BTK,MTMR2,SGCE,PTBP2,KRIT1,USP6,CFL2,SRSF11,SOCS6,CNOT8,NRXN3,PLAA,C4orf33,CNTFR,CNTN1,AKAP7,ARMC8,AKAP6,SLC4A8,ABI3BP,SLC35F1,FAM171B,PREPL,RBM39,NCOR1,GDA,TRIM69,AATK,SNCAIP,OSBPL3,SOCS5,PHF14,GREB1,ARHGAP32,RIPOR2,ARHGAP24,LONRF1,DGKB,TMEM170A,PABPC5,AIF1L,PITPNC1,TMEM130,ZNF582-AS1,GRIN3A,DMD,CDON,RCAN1,DNM1L,EBF1,EDNRA,EDNRB,ANKRD46,RASGRP1,FAM13A,PHF20L1,EGR3,PLEKHA1,PAN3,RCAN2,ARMCX1,FAM198B,ZNF461,SCML2,ST3GAL6,FGF1,POLK,ATP13A4,EFCAB2,ZBED3,PDLIM5,TPK1,SARAF,MEGF11,CHL1,GABRG2,DISC1,KIAA1841,NEU3,SULT1C4,MSTN,SESN1,MALT1,LUZP2,GPD2,GRIA2,FAM107A,RASSF8,FRMD3,NCKAP1L,HNMT,NEGR1,CELF5,RBPJ,IL12A,SLC35G1,KCNN3,STXBP5,NCOA7,SMAD1,MARK1,LYPLAL1,MAT2A,MATN2,MBNL1,MEIS1,ZNF680,ADAM22,P2RY13,NELL2,NF1,DNHD1,IGSF11,CNTN3,DPY19L2P2,PDE4B,GNG2,TMIE,PIK3R1,CCSER2,ZFYVE21,PLIN1,STRN3,ING3,POU6F1,PPM1B,PPP2R5E,PPP3CA,RANBP3L,PRKACB,MAPK10,SAMD9,PTN,TMEM260,PTPRG,C1orf109,PEX2,PID1,CEP97,RAD51D,RAP1GDS1,ZNF493,OXR1,RASGRF2,KHDRBS2,MSANTD2,PRIMA1,PBRM1,RNASEL,CARF,ROBO2,NEK11,GLDN,ADAL,TRAPPC13,AP1AR,SATB1,SUPT20H,SCAF8,CPEB3,FBXO11,ST6GAL1,CNKSR2,ANKRD6,BTBD3,KANSL3,TET1,DMRTC1,MYH15,RCOR3,LIMCH1,USP33,PDZD2,TRERF1,CLSTN2,ITPRID2,MPRIP,STAU1,KANK1,ANKRD28,CAMTA1,ZFP90,ZEB1,TRIM2,SYNE1,NSD1,PCDHA5,CCDC173,PMS2CL,KHDC1,ZFPM2,AKTIP,SLC44A1,TIAM1,MTMR14,TLR4,ERCC6L2,FAM124A,NPL,TRIO,SGK3,EIF4ENIF1,USP1,ZNF709,CCDC14,VLDLR,VSNL1,LAT2,ZNF708,KCNT2,TRIM9,CELF4,ZNF189,ANKS1B,EMSY,PRTFDC1,RNF103,WNK3,EPM2A,RTN4,NETO1" MicroRNA hsa-miR-603:mirSVR_highEffct hsa-miR-603:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.59E-101 3.13E-97 9.87E-100 9.09E-99 253 1407 "GALNT16,ADD1,PTCHD1,BEND6,INTS2,KLHL13,TAOK1,SMIM17,ARHGAP20,AMPH,OGT,ANK2,EP400,PKP4,PARG,EPB41L5,BCAS1,TNRC6C,SHROOM2,MADD,CASK,NCOA1,NUMB,DYNLL1,TMEM108,ATP1B3,MPDZ,PROM1,BMPR1B,SYNJ2,FUBP1,NAE1,WASF1,VXN,SPAG9,KRIT1,METTL6,CDH2,MAGI1,TIGD7,CFL2,SRSF11,SOCS6,CHN2,QKI,HECTD1,RAB26,ARHGEF6,AHCTF1,ZFP28,CPS1,SEC31B,RBM39,ANKRD44,GDA,SEC24C,CSNK1G3,PLXNA4,PITPNM3,PHF14,USP6NL,LONRF1,LIN54,MATR3,KIAA0586,TMEM170A,DAPK1,SPATA2,YTHDC1,KIAA0319,SGSM2,DMTF1,CASP8AP2,DPYSL2,ARRDC4,ECM2,MAMLD1,E2F6,EDNRA,SEMA3D,FSD1L,PHF20L1,GOLGA7,PLEKHA1,SRPK3,PCOLCE2,TMEM35A,CALCRL,RAB9B,MRPL37,TLR7,NSRP1,SH3YL1,ACSL4,GTF2IRD2,FGFR1,AMOTL2,SUCO,SEC23B,IP6K2,SYNCRIP,RGPD5,PSD2,NBEA,NSG1,STAU2,MEGF10,GAA,HRASLS5,GCNT2,SESN1,PCDH17,GGTA1P,HPGDS,MSL3,ZNF638,KDM2B,HTATSF1,KCNMB4,ZNF782,GPR34,DIDO1,GSN,RNF165,PSIP1,RASSF8,MSL1,ZNF181,RBPJ,KIT,STXBP5,L1CAM,SYTL4,PIK3AP1,POC1B,AFDN,BLOC1S2,MSR1,MYO9A,P2RY13,NF1,NPY,SETD4,GPR137C,PDE3A,NALCN,RETREG1,FAM216A,PLCL1,ING3,RETREG2,MINDY2,CEP41,PKIA,HYDIN,SNRK,PTPRD,PTPRG,PTPRN,CEP97,TMEM255A,USP47,RAD17,SH3TC2,FAM184A,ZNF493,RADX,RDX,RET,FIGN,RGS4,RIC8B,NUDT11,PBRM1,CARF,CCDC102B,FBXW7,LRRK2,ZNF354C,NCBP3,AP1AR,SALL1,SATB1,ATXN2,ATXN7,SCP2,FHOD3,NLGN1,SEC31A,SLA,ATF7IP,SNAP25,MBD5,TMCC1,USP33,SP4,PEG10,ZC3H13,CDK19,RBM26,SPART,ZC4H2,ERBIN,ELOVL4,SEPT8,TTBK2,SYNE2,PLCB1,COBL,MMS19,TACR1,PJA1,AGTPBP1,TBCEL,TCEA1,SATB2,ZEB1,SLC19A3,PCDHB6,PCDHB3,AP4E1,SLC44A1,ASXL3,TMPO,PRRT1,CSMD1,RGMB,NR2C2,ANKRD20A2,TTC3,SGK3,RPL7L1,EIF4ENIF1,USP1,VGF,WIPF1,GUSBP1,PCDH20,ZBTB14,MKRN3,LYPD6,CELF4,ZBTB38,FSTL5,UPF3A,CADM2,FIP1L1,PLSCR4,PARP11,DOCK8,PHTF2,IFT88,RNF146" MicroRNA hsa-miR-4325:mirSVR_lowEffct hsa-miR-4325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.67E-101 3.17E-97 9.98E-100 9.19E-99 256 1441 "SYN3,ACADM,CLK4,FMNL2,ESYT2,PTCHD1,MTUS1,CC2D2A,SMIM17,SEMA6A,ALCAM,PITPNM2,AMPD2,ANK2,PKP4,EPB41L5,USP37,ARHGDIA,MARCH3,MARK4,NCOA1,DPY19L3,RIPK1,KSR1,DST,ST3GAL5,SYNJ2,MTMR2,C5,CACNA1B,CAMK2A,CAMK2B,CERS5,MTMR7,SEPT7,CDO1,RCBTB2,SRSF11,NDST3,LHX2,RAB28,DGCR9,FBXO7,QKI,CNGA3,AKAP5,SLC4A8,CPS1,C2CD2,HINFP,ANKRD44,CSF1R,SEC24C,ARHGEF10,CSNK1G3,VCAN,DZIP3,ERC2,UBXN2A,RIMS2,HDAC9,ARHGAP32,ZFYVE16,EARS2,RASSF2,IP6K1,GIT2,ZBTB24,PLPPR4,SACS,SV2B,SPOCK3,DMD,DMTF1,DPP6,PDCD6IP,DTNA,ABCC5,DNM1L,E2F5,EDIL3,EDNRA,EDNRB,HIPK3,KLHL5,TMTC1,APH1A,MBNL2,RASA4,GOLGA7,EIF5,COPS4,STARD3NL,CHST15,STRADA,FGF13,FHL1,MEX3B,SYNCRIP,EVL,C2orf88,UFM1,MSANTD4,GALNT15,GALC,B4GALNT1,C15orf41,DISC1,TUBGCP4,GFER,PPARGC1A,COPS8,HPGDS,DBF4,SPIN1,GNG4,FERMT2,PRUNE2,GPR34,GPR37,RNFT2,GUCY1B1,HAS2,ZHX1,GABARAPL2,SYNPO,HSF2,IGF1,ZNF678,JAK2,KCNN2,TTYH2,LAMP2,SFXN5,NCOA7,MAN2A2,MAP2,MARK3,MATN2,MATN3,MBP,TM6SF1,LRP1B,MEF2C,MEIS1,AFF1,COMMD5,NCAM2,ALDH1L2,NFIX,NOVA1,NPTX1,SLC11A2,IGSF11,OPRL1,PDE4D,PFKFB2,XRN1,NLE1,EPB41L4B,PPP2R2C,PRKCB,MAPK9,MAPK10,CNTLN,ELOVL2,PTPRO,TUG1,PPP2R3C,REV3L,RGS4,RIC8B,PBRM1,ROBO1,ROBO2,ZC3H14,SGSM1,TCP11L1,RYR3,RMI1,SATB1,ATXN2,SCP2,FOXRED1,HSPA4L,PPM1E,SHC4,FNDC3A,FAM81A,BTBD3,DHX30,SLC6A8,SLC8A1,CCDC88A,TRIM67,CPEB4,COA1,RCOR3,INAVA,LIMCH1,PDZRN3,SOX11,ZSWIM8,SP4,ZNF423,ZNF302,SAMSN1,RGL1,ADHFE1,PHLDB1,KANK1,PLCB1,C12orf76,CAMTA1,DNMBP,TBL1X,DMXL2,USP22,CLASP1,PCDHB7,PCDHB6,FRYL,PMS2CL,C18orf54,ITGB3BP,SLC44A1,TIAM1,R3HDM1,TNS1,TPM1,CDK20,NPL,METTL3,HIRA,FAM155A,USP1,VLDLR,GUSBP1,ZNF28,TRIM9,LYPD6,ZBTB38,ZNF189,CADM2,RNF103,TMEM178A,HRASLS,AMN1,UBE3B,KAT6A,HNRNPA3,CASC15,RNF170,MSRB3,FXR1,FRMD6" MicroRNA hsa-miR-204:mirSVR_highEffct hsa-miR-204:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.73E-101 3.21E-97 1.01E-99 9.25E-99 270 1603 "KCNH8,XKR4,NDRG3,KLHL32,CCDC85A,GALNT13,ADD2,ADORA2A,PWWP2A,ESYT2,AP2A2,INTS2,MTUS1,TAOK1,ADGRF5,C1QTNF3,SEMA6A,SPOP,ALCAM,BIN1,ZFAT,UPRT,SEMA4G,SPTBN4,RGS20,MARCH3,STK33,TTLL9,SEC11C,RGS9,PROM1,NAE1,C5,KALRN,CCNH,MTMR7,CDH2,L3MBTL4,SOCS6,CHN2,MS4A7,PLAA,CLCN3,CLTC,FHL5,ARMC8,AKAP6,COL4A5,AHCTF1,ZNF521,RBM39,HAPLN1,RNF14,GDA,TRIM69,SUSD5,VAC14-AS1,DZIP3,ERC2,RIMS2,RUBCN,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,CENPL,LONRF1,DGKG,TMEM170A,DAPK1,DBI,ARMCX4,ARMCX2,DGCR5,TIAM2,FBXL5,DDX46,RHOBTB1,PLPPR4,SPOCK3,FAM107B,ZNF582-AS1,CHRDL1,GRIN3A,DMD,HS3ST2,DMTF1,SLC12A6,PDCD6IP,RCAN1,DTNA,FRY,CELSR3,APH1A,EGFR,KMT5B,EGR3,RASA4,C8orf37,EPHB1,RABEPK,SRRM1,SIRPB1,RPS6KC1,ACSL4,SCML2,STRADA,FER,FGFR1,POLK,SUCO,ATP13A4,SLC37A3,NBEA,SMC2,RASL10A,ATP6V1H,ZNF605,KHDRBS3,NSG1,STAU2,AP4B1,GABRG1,GABRG2,ZNF274,ERAP1,C15orf41,LRRC37A6P,GCNT2,GDF9,PCDH17,GGT7,PPARGC1A,TOX3,ZNF638,RAB40B,GPT2,GPD2,FUT10,GRIA2,MAP4K5,IRAK3,RASSF8,HAS2,GABARAPL2,SMAP1,IRF8,LRRCC1,INSM1,JAK2,KCND2,STXBP5,SYTL4,HECTD2,NCOA7,ZFYVE27,MBNL1,MEIS1,MGAT3,MMP16,NF1,NOVA1,NTRK2,PCDH9,PDE4A,PDE4B,PDE4D,PIK3R1,FAM218A,RETREG1,XRN1,GPSM2,SMIM7,LRP12,SEPT4,POLR2F,MAPK9,VPS13C,GDPD2,SNRK,PIGG,SPDL1,PTPRB,PTPRD,EML5,PTPRE,C1orf109,PTX3,PID1,CEP97,TMEM255A,USP47,CCDC40,ZNF793,HKR1,ZDHHC14,GTDC1,ZFHX4,CARF,GSTCD,CCDC25,FBXW7,TCP11L1,KCNIP3,ATXN2,FNIP1,ARX,FERMT1,KIF16B,SHC4,FHOD3,KANSL3,BTBD7,MYH15,RCOR3,SNRPN,TRERF1,MYCBP2,KDM4C,ZNF423,ZC3H13,RBM26,ATP10B,ZC4H2,SS18,ERBIN,ZSCAN29,ELOVL4,RGL1,SYPL1,TACC1,ANKRD12,PJA1,CAMTA1,DNMBP,TCF4,SATB2,ZEB1,TCF12,SYNE1,FRYL,SIRT1,GPR161,ERCC6L2,TMPO,NPL,RPL7L1,FLRT2,PLEKHH2,VSNL1,ZNF781,GUSBP1,XRCC4,MICU3,TMEM237,EMSY,STOX2,PRDM8,VPS35L,GAL3ST3,SLC17A7,PLSCR4,RGS7BP,DOCK8,ST7,FBXO36,RNF170,JPH3" MicroRNA hsa-miR-130a:mirSVR_highEffct hsa-miR-130a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.03E-101 3.37E-97 1.05E-99 9.70E-99 251 1385 "CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,SPARCL1,SPOP,SRPX,FAM135A,LRCH2,LCORL,PHF12,APAF1,SHROOM2,LINC00173,STK33,NCOA1,STX16,ZNF583,DPY19L3,ADAM23,TTLL9,ADGRB3,NRP2,DST,SYNJ2,C5,THSD7A,KALRN,CAST,USP6,TIGD7,CFL2,PLAA,CLTC,CNR1,AKAP7,FAM149A,AKAP6,ABI3BP,AHCTF1,MYRIP,CLOCK,CREM,GDA,CSF1,LRIG1,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,LONRF1,SPATA2,YTHDC1,ELMSAN1,FBXL5,KIAA0319,RHOBTB1,SPOCK3,WDR20,RAB39B,CPEB2,DPYSL2,ABCC5,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,KMT5B,EGR3,CERCAM,PAN3,ENPP6,RASL12,ACSL4,MED12L,FGF11,FGF14,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,NBEA,TPK1,MEGF10,GALC,B4GALNT1,ERAP1,GCNT2,ARFIP1,SESN1,ADAM28,MALT1,RAB30,TNRC6A,KDM2B,MAP7D2,RAB40B,FERMT2,PRUNE2,GRB10,CIT,RNF165,BACH2,HNF4G,NEGR1,IRF8,ZIC5,LRRCC1,ZNF678,KCNN3,CREG2,LIG4,MAP4,MATN3,MBNL1,LYRM9,MYO9A,ZNF862,MYT1,NEK1,NFE2L2,CNOT4,NTRK2,OCRL,LOC100128398,PCSK5,PDE1C,DUSP26,CCSER2,ZFYVE21,JAKMIP1,PURG,LRP12,SCHIP1,PPM1B,PSD,MTMR10,EML5,PTPRG,PID1,CEP97,RBBP8,KHDRBS2,ZDHHC14,RDX,RET,ERI2,SLC25A36,KLHDC8A,CARF,ROBO2,EPHA10,ATP8B4,LRRK2,CLIP1,RTN1,PEAR1,SEC14L1,ARX,KIF16B,CHD9,SYBU,SEC31A,BTBD3,WDR47,SEPHS1,SLC8A1,CCDC88A,BTBD7,SNAP25,SNCA,KIF13A,USP33,TRERF1,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD12,MTCL1,CAMTA1,FBXW11,PCDHB4,TEK,DICER1,ZFPM2,ITGB3BP,SLC44A1,BHLHB9,ERCC6L2,R3HDM1,CSMD1,TNS1,TSC1,UBC,FAM155A,CCDC136,WRN,CLDND1,ZIC1,ZNF711,ZNF74,SPHK2,TCEAL7,ZBTB38,REEP1,FSTL5,MAP3K12,MFF,STOX2,PLSCR4,RGS7BP,RTN4,UBE3B,PHTF2,NHSL1,FXR1,FRMD6,SENP7" MicroRNA hsa-miR-644:mirSVR_lowEffct hsa-miR-644:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.30E-101 3.53E-97 1.10E-99 1.01E-98 254 1419 "ASPHD1,ABHD6,SYS1,ADCY6,DPY19L2P4,ZNF608,HACE1,KIAA1324,OSBPL6,TXNDC16,USP35,CEP126,AMPD2,LRFN1,ZFAT,MAP4K3,UPRT,SEMA4G,PLA2G4C,ARSE,CADPS,PCDHGB4,CHID1,ATP1A1,ADAM15,KALRN,VXN,LDB2,USP6,CD86,CD38,CHRNA4,B4GALT6,CLTC,FAM189A2,VAX2,SULT4A1,SRP14-AS1,IQCK,PCYT1B,MAGED1,ABI3BP,SLC35F1,SNCAIP,SEC24C,VAC14-AS1,PDE4DIP,GREB1,KATNAL2,PABPC5,HEPH,RUSC2,PLPPR4,SGSM2,TMCC2,SEC16A,CPEB2,SLC12A6,DUSP9,DNAJB6,EDN1,EDNRA,ANKRD46,HEYL,ASB3,EIF4G2,TENM1,RGS17,MTSS1L,RAB9B,SRRM1,NCALD,VPS26C,ARMCX1,SH3YL1,DLC1,ZNF589,FGF11,FHL1,FLT1,SYT3,ERGIC3,KHDRBS3,CGREF1,ZNF559,NEU3,ALDH1L1,ADAM28,BRD8,TNRC6A,KDM2B,MAP7D2,RAB40B,TDRKH,GPER1,DIDO1,ADAMTS13,SERP2,GRIN2D,ZNF496,FAM107A,GUCY1A1,PADI2,MIER3,NEGR1,HSF2,SHISA6,SMAP1,MYLK2,ZIC5,RBPJ,KNDC1,SCIN,IL6ST,INSM1,C2CD4C,LINC00634,HECTD2,ZFYVE27,MAP6,MBNL1,MEIS1,MEIS2,XRRA1,GIT1,MSR1,N6AMT1,MXI1,MYO7A,RTL5,NEXMIF,MYT1,ALDH1L2,NPR2,SLC11A2,SMIM11A,TBC1D25,LOC100128398,PCDHGC3,PCDH9,ENPP2,PDPK1,PFKFB4,PLIN1,PLXNB1,POLR2F,PPARA,PPP3CA,PRKAB2,CEP41,HYDIN,MASP1,BCAS3,GDPD2,TMEM104,CNTLN,ELOVL2,PTK2,ACSM5,NKAIN1,RASGRF2,ZDHHC14,ZMAT4,MORC4,GTDC1,RGS12,RNASEL,TMLHE,ALG9,RORB,RPL15,BAALC,ATP8B4,GLDN,ATAT1,KCNIP3,SCP2,CASC3,SH3BP2,FHOD3,ST6GAL1,SYBU,FAM81A,CCDC88A,SLC11A1,SLC12A4,ATF7IP,ARFGAP1,ANKRD36,MBD5,SNRPN,BDP1,IZUMO4,KDM4C,PEG10,SPTAN1,IQSEC2,LHPP,LMO3,ATP10B,ITPRID2,SSPO,COBL,MTCL1,FAM208A,PDLIM2,TBCEL,DMXL2,TPCN2,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,TNS2,HIF3A,GPR161,MTMR14,RIMBP2,CSMD1,C9orf85,NR2C2,DCBLD1,CLHC1,HIRA,UCHL1,PLEKHH2,CLIP2,LGI4,MKRN3,LYPD6,AMZ1,ZNF213,SMARCAD1,LINC02210,STOX2,ADAMTS9,VPS35L,GAL3ST3,NAV3,URM1,PPP1R3F,CASC15,ACTR3B,GAN,LAS1L,JPH3" MicroRNA hsa-miR-1290:mirSVR_highEffct hsa-miR-1290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.19E-101 4.03E-97 1.25E-99 1.15E-98 268 1581 "RALGAPA1,NCKAP5,GALNT13,PLEKHH1,DPY19L2P4,PCDH19,NME5,OSBPL6,SPARCL1,ABCD2,UNC79,FAM135A,BEGAIN,AMPD3,AMPH,LRFN1,PHF12,APOC1,BCAS1,DYNLL1,SLC4A4,ZNF583,DPY19L3,TTLL9,BACH1,BCL7A,CFLAR,PROM1,ARHGEF7,JAZF1,CACNA2D1,CABP7,THSD7A,KALRN,CAMK2A,ISPD,CBLN1,C1orf52,MAGI1,SRSF11,CHN2,CHRNA4,TPP1,FAM19A5,QKI,HECTD1,FHL5,AKAP7,IQCK,FAM149A,RTTN,AKAP12,CLIP3,TRIM69,ARHGEF10,VCAN,PHF14,PUM1,FAM131B,CCDC144A,HDAC9,PABPC5,ZNF804A,ZBTB24,TIAM2,TMEM130,POM121,KIF19,DMD,CPEB2,PDCD6IP,FAM78B,MAMLD1,WDPCP,EDNRB,KLHL5,EGFR,MBNL2,KMT5B,GOLGA7,EIF5,PLEKHA1,RGS17,C8orf37,GPHN,IGSF6,CDKL3,DNAJC27,RASL12,F8,CLVS1,ACSL4,GORAB,SEC24B,FER,MED12L,FGF12,POLK,PCYOX1,ANKFY1,TMEM107,CAMKK2,CELF1,FYB1,C15orf41,DISC1,TUBGCP4,MSTN,ARFIP1,MALT1,ZNF638,GNAL,FERMT2,ADGRA3,GPR34,GRIA2,FAM19A2,RNF165,PSIP1,RNFT2,HAS2,MIER3,AGBL5,NKD1,RBPJ,TJAP1,IL6R,SLC35G1,IPO5,STXBP5,PAXBP1,HECTD2,NCOA7,PIK3AP1,MAN2A2,MAP2,MATN2,MATN3,TM6SF1,MMP16,ZNF680,MSR1,ZNF92,LAYN,BEX5,VWA2,CNOT4,NOVA1,SLC11A2,NUCB2,IGSF11,OGG1,LOC100128398,P2RY1,CNTN3,ETFRF1,NLGN3,PIK3C2A,SNX10,RETREG1,GPSM2,MTRF1L,TRHDE,LRP12,EPB41L4B,SH3KBP1,PPP2R2C,RASGEF1B,MAPK9,HYDIN,SAMD9,VPS13C,WBP1L,SNRK,PTK2,TMEM260,PTPRN2,ZNF615,PPP2R3C,TMEM255A,SH3TC2,OXR1,RADX,ZDHHC14,DPF2,ERI2,TMLHE,KLHDC8A,GSTCD,ROBO1,CCDC102B,NEK11,RPL15,FBXW7,ADAL,PTGR2,RTN1,NCBP3,AP1AR,RMI1,SCP2,TRA2B,FNDC3A,FHOD3,CNKSR2,PREX2,PPP4R3A,WDR47,SEPHS1,CCDC88A,BTBD7,ATF7IP,ZNF667,MBD5,KIF13A,SNRPN,TMCC1,TRERF1,SP2,STAU1,TTBK2,NECAB1,JMJD6,PRRC2C,SYN2,C12orf76,ANKRD12,AGTPBP1,FBXW11,SIN3B,SATB2,ZFP90,CRTC1,GPR161,CDK20,WBP2,SMUG1,TRO,CLHC1,RPL7L1,FAM155A,BCL2L13,VSNL1,WIPF1,ZNF781,ZNF711,ZNF32,TRIM9,ZNF74,CELF4,REEP1,FSTL5,EML6,ZNF189,EMSY,CADM2,PRTFDC1,ADAMTS9,KCNAB1,PDSS2,RGS7BP,FZD3,MARCH8,KAT6A,HNRNPA3,NLRP3,FXR1,FRMD6" MicroRNA hsa-miR-1322:mirSVR_lowEffct hsa-miR-1322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.56E-101 4.23E-97 1.31E-99 1.21E-98 259 1477 "RALGAPA1,CLK4,FMNL2,KLHL32,TMEM132B,AXIN2,BRAP,ESYT2,BEND6,SLC24A4,OSBPL1A,CC2D2A,ZNF578,PCDH10,APC,EPB41L5,VAT1L,TNRC6C,PCDHGB4,DPY19L3,BBS2,MTMR2,JAZF1,SGCE,C5,CA12,CALB1,KALRN,RUNX1T1,ARHGEF25,LRBA,LOC730101,TIGD7,CCPG1,FOXN3,ASIC3,CHN2,CLTC,MAP4K4,CNR1,AKAP6,ZNF521,CPS1,OSBPL3,PDE4DIP,CST3,PLXNA4,RUBCN,SNPH,ZFYVE16,ZNF337,TBC1D5,KCTD8,TMEM170A,ARMCX2,JAKMIP2,DGCR5,MFAP3L,KLHL3,WDR20,ZNF582-AS1,HS3ST2,NR1D2,DOCK2,PDCD6IP,ARRDC4,ECM2,DNM1L,GOLT1B,EDNRA,ANKRD46,TMTC1,OPTN,YAF2,AASS,EIF4G2,IRAK4,TENM1,SIRPB1,EXTL2,KATNAL1,ARMCX1,TUBA1B,ZNF589,SLC9B2,FGF1,FGFR1,SCARA3,TRMO,NBEA,TPK1,ZNF605,CGREF1,AP4B1,TMEM8B,INPP5K,CPLX2,CPLX1,IGSF5,SULT1C4,MSTN,MALT1,RAB30,TNRC6A,MSL3,LOXL3,ADGRA3,TDRKH,MCHR1,TMEM121B,GRM2,FAM19A2,AP4S1,RABL2A,GUCY1A1,ATOH8,NCKAP1L,HSPA1L,IDH3A,C2orf72,KCND1,KCND2,KCNN2,A1BG-AS1,SYTL4,HECTD2,NCOA7,GPR155,MBD1,CHIC1,MIA2,MSR1,NRBP2,MYO5A,MYO6,NDP,NF1,ALDH1L2,NFYA,NPY,SLC11A2,NRCAM,SETD4,CNTN3,PCDHGC3,GNG2,ZNF655,PLCB2,MTRF1L,STRN3,LRP12,PPP2R5E,KANSL1,TMEM104,ZSCAN32,PTPRB,PTPRD,PTPRO,ACSM5,USP47,ZCWPW1,TRIM68,REV3L,PBRM1,KLHDC8A,ALG9,ARMC5,CARF,GSTCD,RORB,ELP2,MRAP2,LRRK2,RMI1,ATXN2,LRFN5,SCP2,FNIP1,GALNT10,FAM102A,SH3GL3,AMBRA1,FBXO11,SLC6A8,SLC9A5,SLC12A2,ELMO2,BTBD7,LGI3,SLC22A4,MBD5,TMCC1,USP33,FAM219A,TRERF1,BDP1,FNBP1,ZSWIM8,ERC1,PEG10,CDK19,NFASC,CLASP2,ELOVL4,SEPT3,SYN1,COBL,TACR1,PJA1,EXOC7,KLHL4,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,DOCK9,PCDHB10,PCDHB4,ITGB3BP,GPR161,SLC44A1,TMEM9,HEY1,ERCC6L2,LRRC8A,BEX4,TPM1,CDK20,C9orf85,RUSC1,MTCH1,VLDLR,RICTOR,GUSBP1,XRCC4,MICU3,TRIM9,ZNF74,ZNF184,EML6,SLC38A1,STOX2,GAL3ST3,EPM2A,FAM13C,FZD3,RTN4,UBE3B,NETO1" MicroRNA hsa-miR-26a-2*:mirSVR_highEffct hsa-miR-26a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.17E-101 4.57E-97 1.41E-99 1.30E-98 262 1512 "ACADM,NCKAP5,KDM5D,XKR4,FMNL2,BRAP,PLEKHH1,KIAA1211,ADRA1D,OSBPL1A,CC2D2A,TAOK1,ADGRF5,C1QTNF3,ALCAM,PCDH10,FAM135A,ALK,OGT,DPP10,LRCH2,CCDC146,TNRC6C,CASK,TMEFF1,ARNTL,ZBTB10,DYNLL1,ATP1A1,SLC4A4,RNF182,ADGRB3,BBS2,BID,CFLAR,DST,SYNJ1,RAB29,CA8,CALM1,KALRN,KRIT1,C1orf52,LRBA,ZMYM4,B4GALT6,ABCG2,QKI,ARMC8,TBPL1,AHCTF1,ZFP28,SLC35F1,CREM,RBM39,ARHGEF10,PDE4DIP,DZIP3,ERC2,PHF14,GREB1,RIMS2,USP6NL,TCAF1,DCAF8,MATR3,KCTD8,DAPK1,PABPC5,BRINP1,MFAP3L,FBXL5,DDX46,CHRDL1,EXOG,GRIN3A,RAB39B,DMD,NR1D2,DMTF1,DPP6,DPYSL2,ECM2,ABCC5,DNM1L,GOLT1B,WDPCP,ANKRD46,RASGRP1,OPTN,PHF20L1,SUGP2,AASS,PLEKHA1,ING4,C8orf37,CALCRL,RABEPK,TLR7,ADGRV1,CLVS1,FAM198B,ACSL4,SCML2,CEP78,FCGR3A,FER,MED12L,SYNCRIP,ERGIC3,ST6GALNAC3,GABRG2,TRAF3IP2,FAM120B,DISC1,GCNT2,SULT1C4,WASHC2A,MALT1,LYVE1,TXNL4A,TCERG1,HPGDS,GLYR1,GLUL,ZNF638,ZNF782,GRIN2C,FAM19A2,RNF165,ADAMTS6,RASSF8,EID2B,SOWAHA,IL12A,ZNF678,SLC35G1,KCNB1,KCND2,LMO2,LSAMP,MARK1,MEIS1,SRSF12,NRBP2,NEK1,NELL2,NF1,SLC11A2,NRCAM,IGSF11,OCRL,CHAMP1,CNTN3,PCDH9,PCSK5,PDE4D,PFKFB2,OLA1,PIK3C2A,FAM218A,FAM216A,PRIMPOL,SH3KBP1,MINDY2,TATDN3,RANBP3L,MAPK9,HYDIN,DIRAS2,DCHS2,SAMD9,SNRK,PIGG,ANKHD1,BDNF-AS,TMEM260,PTPRG,USP47,FAM66C,SH3TC2,ENOX1,KHDRBS2,CRTAC1,ERI2,RGS4,RGS12,RIC8B,GSTCD,ROBO2,CCDC102B,ATP8B4,MEG3,ZNF568,ZNF331,SCAF8,FBXO11,SLC8A1,CPEB4,ZNF667,ANKRD36,SNCA,SNRPN,SP4,PEG10,RBM26,LMO3,ATP10B,CLASP2,TROVE2,SSTR2,NKAIN2,NXT2,DIP2A,SULF2,KLHL7,PRRC2C,SYNE2,VPS13A,TMEM150C,SYT1,COBL,TACR1,DNMBP,KIAA1107,WSCD1,SATB2,ZEB1,TRIM2,DOCK9,SLC19A3,PCDHB7,PCDHB3,NSD1,GPRIN3,FRYL,SIRT1,ZFPM2,TNS1,CDK20,RGMB,SYNPO2,METTL3,TRIO,ZNF610,UBE2H,CCDC14,WIPF1,XPO1,ZBTB14,KCNT2,TMEM237,FSTL5,ZNF184,EML6,ANKS1B,UPF3A,SLC30A4,EPM2A,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-361-5p:mirSVR_lowEffct hsa-miR-361-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.92E-101 5.55E-97 1.71E-99 1.57E-98 275 1666 "VWA5B2,NDRG3,PWWP2A,KIAA1211,PCDH19,OSBPL8,ALCAM,ABCD2,ARHGAP20,UNC79,OGT,CDC42BPA,LRCH2,EP400,PARG,APBB2,UPRT,PPP4R4,ARRB1,NCOA1,DYNLL1,SLC4A4,BACH1,FUBP1,NAE1,WASF1,IL33,CACNB4,CALB1,KALRN,HAP1,VXN,CH25H,ISPD,LDB2,USP6,MTMR7,ZMYM4,DLGAP1,CFL2,SOCS6,TPP1,C4orf33,ARHGEF6,COL9A1,RCHY1,CNRIP1,SLC35F1,ANKRD44,GDA,CSF2RA,VAC14-AS1,PLCXD3,PUM1,ZSCAN23,CCDC144A,KIAA0408,ZFYVE16,LIN54,MATR3,KIAA0586,KCTD8,IST1,DAPK1,SCRN1,ARMCX4,JAKMIP2,ZBTB24,TIAM2,FBXL5,KIAA0319,PLPPR4,EXOG,NR1D2,DNM1L,E2F5,EDNRB,FSD1L,PHF20L1,COPS4,C3orf18,VPS13B,EPB41,LRRC17,EPHB1,ERBB4,CEP85L,ZNF549,RPS6KC1,DLC1,FKTN,ZNF589,FGFR1,PCYOX1,SYNCRIP,FLT1,EFCAB2,JKAMP,HVCN1,PDLIM5,TPK1,KHDRBS3,CSPG5,NSG1,STAU2,ERAP1,SIGLEC8,DISC1,GCNT2,MSTN,PCDH17,GHR,HPGDS,MSL3,LILRB4,PRUNE2,FUT10,DIDO1,GRM8,FAM19A2,KAT7,MUM1,IRAK3,RASSF8,ARHGAP36,MIER3,AGBL5,HNF4G,HNMT,ZDHHC15,TCEAL6,DHX35,HSF2,MSL1,NKD1,LRRTM1,METTL21A,KCNN1,STXBP5,PAXBP1,NCOA7,MAPT,MBP,LRP1B,MEIS1,MID1,XRRA1,MMP16,MSR1,NRBP2,MYCN,LYRM9,TCEAL5,BEX5,NFE2L2,ALDH1L2,NFIX,NOVA1,DNHD1,NPR2,NTRK2,OCRL,CHAMP1,OGG1,CLDN11,P2RX7,PRTG,PDE4D,PDE1B,SLC10A4,NALCN,RETREG1,XRN1,KCTD15,PURG,PMP22,STRN3,LRP12,EXOSC10,EPB41L4B,DRAM2,PPP2R2B,PPP2R5E,PPP3CA,PPP3CC,BCAS3,PTCH1,BDNF-AS,MTMR10,TMEM260,PTPRB,PTPRE,PTPRG,PTPRO,USP47,ZNF493,RBBP6,KHDRBS2,ZMAT4,RET,RNASEL,CCDC82,SETD5,TMLHE,ALG9,FBXW7,SPIN3,ADAL,STK32B,LRFN5,FNIP1,TNFRSF19,SMPD3,SEC14L1,GALNT10,TRA2B,PPM1E,SHC4,AMBRA1,NLGN1,PKNOX2,SEPHS1,KBTBD4,SLC12A2,MYH15,SNAP25,SNCA,ZNF415,SNRPN,DOP1A,BDP1,SOX11,ZHX3,PEG10,CDK19,ZBTB43,RBM26,LARP4,NXT2,ARHGEF9,PLCB1,SYT1,ANKRD12,PJA1,TAF9,TCF4,DOCK9,USP32P1,ARHGAP9,GPRIN3,SLC44A1,DOK6,SYNPO2,TRIO,RUNDC3B,RUSC1,TSC1,EIF4ENIF1,UBE2H,FLRT2,WIPF1,CLDND1,ZIC1,LYPD6,REEP1,DPYSL5,DHX33,GDPD5,PRDM10,TUBA1A,SIGLEC10,FAM47E,DOCK8,PHTF2,NETO1" MicroRNA hsa-miR-620:mirSVR_lowEffct hsa-miR-620:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-100 6.43E-97 1.97E-99 1.82E-98 275 1667 "CLK4,C3orf14,NCKAP5,SYS1,ACTN1,USP31,KIAA1211,DPY19L2P4,SLC24A4,AP2A2,WDR35,OSBPL8,AK2,SEMA6A,ALCAM,PCDH10,ANK2,SUGT1P4-STRA6LP-CCDC180,LGR5,SFMBT2,MARK4,EIF4G3,ATP2B2,SLC2A11,ADAM15,BACH1,LINC00847,RGS9,CFLAR,BTK,CACNA1G,RAB29,ZNF555,PTBP2,VXN,SPAG9,CCNH,P2RX6,C1orf52,ZMYM4,LARGE1,TIGD7,CCPG1,NUMBL,RAB28,TPP1,STOML1,FBXO7,QKI,SRP14-AS1,HECTD1,FAM149A,COL4A5,TOGARAM2,CLOCK,PREPL,CREM,SNCAIP,ERC2,APPL1,UBXN2A,RUBCN,TCAF1,ZFYVE16,TBC1D5,DGKB,GIT2,KLHL3,POM121,SV2B,DLX1,GRIN3A,USP3,PHC2,RASGRP1,EGFR,RASA4,ELN,SRRM1,ERBB4,MRPL37,SIRPB1,MRVI1,FCGR3A,FCGRT,FKTN,FDFT1,FER,GTF2IRD2,POLR1B,SUCO,PCYOX1,ATP13A4,ANKFY1,NOP56,PDLIM5,ATP2C1,SARAF,HRASLS5,GABRB3,GAD1,ERAP1,ACSS1,TUBGCP4,SESN1,ADAM28,GHR,BRD8,TOX3,AIFM3,CBX1,DCLK2,PRUNE2,PCLO,PLCD4,CIT,FAM107A,GUCY1A1,HSF2,KIAA1755,DISP2,SLC35G1,CDH20,KCNN2,CREG2,STXBP5,PIK3AP1,GPR155,MAP4,MAT2A,MBD1,CHIC1,MEF2C,KITLG,PPM1L,NEXMIF,ZNF862,ALDH1L2,VWA2,CNOT4,NOVA1,PCBP3,TBC1D25,PCSK5,PDE1C,GNG2,PFKFB2,PFKFB3,NLGN3,NALCN,PIK3C2A,ZNF655,CCSER2,PCDH18,PMP22,MAPKAP1,PILRA,PPP3CC,RASGEF1B,PKIA,DCHS2,MASP1,RELN,BCAS3,CNTLN,TMEM145,ZSCAN2,TUG1,CEP97,FAM66C,IQSEC3,FAM184A,RBBP6,KHDRBS2,ZMAT4,ERI2,SUGCT,ALG9,ROBO2,CCDC102B,FBXW7,KCNIP1,TRAPPC13,AP1AR,SALL1,SEC14L1,SCAF8,SH3BGR,FHOD3,BTBD3,KANSL3,SLC6A8,KBTBD4,NAPB,MTERF2,BTBD7,EPC1,ZNF667,SMARCA4,MAST1,CDK5RAP2,ANKRD36,MBD5,CABCOCO1,FAM126B,DOP1A,BDP1,SP4,UHRF1BP1L,ZC3H13,SPTAN1,CDK19,TROVE2,ITPRID2,ZC4H2,NKAIN2,RGL1,VPS13A,COBL,SLC37A2,ANKRD12,MTCL1,PJA1,TBL1X,KLHL4,SIN3B,DMXL2,SATB2,TPCN2,OBSL1,PCDHAC2,PUM2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,AKTIP,ENHO,MTMR14,RIMBP2,NPL,C9orf85,SYNPO2,TSN,ANKRD20A2,TSC1,SGK3,RPL7L1,BCL2L13,TBC1D15,LMF1,TSPAN11,WIPF1,CLDND1,ZIC2,SPIRE1,SMARCAD1,SLC38A1,ADAMTS9,HPS4,URM1,SLC17A7,PDSS2,UBE3B,SMIM8,CASC15,FAM219B,TRAM2-AS1,ST8SIA2,SENP7,JPH3" MicroRNA hsa-miR-21:mirSVR_lowEffct hsa-miR-21:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-100 7.84E-97 2.40E-99 2.21E-98 257 1458 "BRAP,KIAA1211,ADRB2,PCDH19,ALCAM,PCDH10,FAM135A,GPRASP2,SYT13,PKP4,EPB41L5,APOC1,STK33,MARK4,NUMB,TMEM108,RNF182,DOCK11,TTLL9,BCHE,NAE1,CACNA1G,CACNB4,CALB1,THSD7A,USP6,L3MBTL4,CDO1,COPB2,RAB28,CLCN3,CLTC,CNN3,AKAP7,FAM149A,WHRN,AKAP5,MYRIP,RBM39,AKAP12,RNF14,ANKRD44,LRRC3B,CSNK1G3,APPL1,PLCXD3,PNPLA8,RUBCN,KIAA0408,HDAC9,TCAF1,ZFYVE16,LONRF1,TBC1D5,MATR3,SCRN1,ARMCX2,MFAP3L,DDX46,POM121,RHOBTB1,SPOCK3,DLX1,HS3ST2,MED12,DMTF1,SLC12A6,ACOT8,ECM2,DNAJB6,ABCC5,E2F5,EBF1,SNX29,KLHL5,FRY,OPTN,EGFR,EGR3,COPS4,VPS13B,FCGR1A,SLC9B2,MED12L,PRKAG2,FOXO3,ANKFY1,SLC37A3,EFCAB2,NBEA,STAMBP,KHDRBS3,CSPG5,FYB1,HRASLS5,TRAF3IP2,RAPGEF6,C15orf41,GATM,GCNT2,SESN1,GGTA1P,RUNDC3A,GLYR1,MSL3,GLUL,ZNF638,LOXL3,FERMT2,ADGRA3,GPD2,GPR34,BTN2A1,BVES,AP4S1,ATOH8,HAS2,ZHX1,NCKAP1L,ACOT7,HMGCR,EID2B,MSL1,ZIC5,ZNF678,ITGAM,CDH20,STMN1,PIK3AP1,MARK1,MBD1,MBP,CHIC1,SHC3,MEF2C,MEIS2,KCTD6,MSR1,LAYN,MYO6,NEK1,NF1,NOVA1,NTRK2,OXTR,ETFRF1,PCDH8,PDE3A,PDE4D,PFKFB2,SERPINI1,PIK3R1,FAM218A,CCSER2,SLC25A23,LRP12,MBOAT7,IRX1,MINDY2,PPP2R5E,PRKAB2,RASGEF1B,PRKCB,PIGG,PTK2,PTPN13,PTX3,TUG1,PID1,FAM66C,FAT4,FAM184A,NWD1,OXR1,RBBP6,KHDRBS2,ZDHHC14,RDX,RET,ERI2,FIGN,RNASEL,TMLHE,ROBO2,ELP2,CCDC102B,MRAP2,SPIN3,ZNF568,CCDC112,SCN7A,SCN8A,SH3GL3,PPM1E,SHC4,NLGN1,DZIP1,WDR47,KANSL3,SLC6A11,KBTBD4,SLC12A2,ZFP1,MBD5,SNRPN,FNBP1,SP4,GLT8D1,HECW1,CDK19,ZBTB43,LMO3,ZNF621,SSTR2,ZC4H2,ST5,ELOVL4,CEP68,PHLDB1,STXBP1,NSFL1C,KLHL7,NECAB1,JMJD6,PRRC2C,PLCB1,SYPL1,CUX2,RPGRIP1L,PCDHB6,RNF216P1,TMEM9,ACTR6,CSMD1,TP53BP2,METTL3,SSBP2,CLHC1,SLC35A4,CLDND1,XPO1,ZNF24,ZNF74,ZBTB38,REEP1,FSTL5,EML6,SMARCAD1,INTS3,EMSY,CADM2,FAM47E,SMIM8,PHTF2,JMJD1C,FXR1,NETO2" MicroRNA hsa-miR-1270:mirSVR_lowEffct hsa-miR-1270:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-100 7.99E-97 2.44E-99 2.24E-98 287 1814 "CLK4,C3orf14,NCKAP5,ACTN1,USP31,KIAA1211,DPY19L2P4,AP2A2,OSBPL1A,WDR35,AK2,SEMA6A,ALCAM,PCDH10,DPP10,SUGT1P4-STRA6LP-CCDC180,KCNAB2,LGR5,SFMBT2,MARK4,ZSCAN18,EIF4G3,ATP2B2,SLC2A11,ADAM23,ADAM15,BACH1,LINC00847,RGS9,BID,KSR1,BTK,CACNA1G,RAB29,CACNB4,ZNF555,VXN,SPAG9,P2RX6,C1orf52,ZMYM4,LARGE1,NUMBL,NDST3,RAB28,FBXO7,QKI,SRP14-AS1,HECTD1,CNGA3,FAM149A,TOGARAM2,CLOCK,PREPL,CREM,SNCAIP,CSF1R,CNTNAP2,ERC2,APPL1,UBXN2A,PLCXD3,RUBCN,KIAA0408,GAPVD1,TCAF1,RIPOR2,TBC1D5,DGKB,GIT2,JAKMIP2,POM121,PLPPR4,SV2B,DLX1,GRIN3A,USP3,DNAJB6,PHC2,EGFR,RASA4,GOLGA7,GPHN,SRRM1,ERBB4,MRPL37,SIRPB1,MRVI1,CHST15,FCGR3A,FCGRT,FKTN,FDFT1,FER,GTF2IRD2,POLR1B,SUCO,PCYOX1,ATP13A4,FLT1,ANKFY1,NOP56,TMEM107,PDLIM5,ATP2C1,SARAF,HRASLS5,GAD1,ERAP1,ACSS1,ALDH1L1,TUBGCP4,SESN1,ADAM28,GHR,BRD8,TOX3,AIFM3,CBX1,WDFY3-AS2,PRUNE2,CCDC184,PCLO,PLCD4,CIT,LINC01089,FAM107A,AGBL5,HSF2,LRRC75A,DISP2,SLC35G1,METTL21A,CDH20,KCNN2,CREG2,STXBP5,PIK3AP1,GPR155,MAP4,MAP6,MBD1,MEF2C,KITLG,PPM1L,MMP16,NRBP2,MYO9A,NEXMIF,ZNF862,SFR1,ALDH1L2,NINJ2,CNOT4,NOVA1,PCBP3,TBC1D25,DPY19L2P2,PCSK5,PDE4D,GNG2,PFKFB2,PFKFB3,NLGN3,NALCN,ZNF655,CCSER2,MTRF1L,PMP22,MAPKAP1,STRN3,PILRA,PPP3CC,RASGEF1B,PKIA,DCHS2,MASP1,BCAS3,CNTLN,TMEM145,ZSCAN2,TUG1,ZNF844,CEP97,TMEM255A,FAM66C,FAM184A,KHDRBS2,RDX,ZMAT4,ERI2,PBRM1,SUGCT,ALG9,ROBO2,CCDC102B,FBXW7,STK32B,LRRK2,KCNIP1,TRAPPC13,AP1AR,SALL1,SEC14L1,SCAF8,SH3BGR,FHOD3,ABLIM3,SLC6A8,KBTBD4,NAPB,MTERF2,EPC1,ZNF667,SMARCA4,MAST1,CDK5RAP2,RCOR3,ANKRD36,MBD5,CABCOCO1,FAIM2,FAM126B,DOP1A,BDP1,SP4,UHRF1BP1L,SPTAN1,CDK19,SPART,TROVE2,ITPRID2,ZC4H2,NKAIN2,RGL1,KLHL7,VPS13A,COBL,ANKRD12,PJA1,KLHL4,SIN3B,DMXL2,SATB2,SZT2,OBSL1,PCDHAC2,PUM2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,MTMR14,HEY1,RIMBP2,NPL,C9orf85,RGMB,TSN,ANKRD20A2,TTC3,SGK3,RPL7L1,BCL2L13,TBC1D15,LMF1,WIPF1,ZIC2,SMARCAD1,ADAMTS9,URM1,SLC17A7,PDSS2,UBE3B,SMIM8,CASC15,FAM219B,TRAM2-AS1,MSRB3,KLHDC1,ST8SIA2,SENP7,JPH3" MicroRNA hsa-miR-595:mirSVR_lowEffct hsa-miR-595:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-100 8.89E-97 2.70E-99 2.49E-98 284 1778 "ADCY6,TMCC3,ADD2,UNC5A,RNF150,SLC24A4,INTS2,CASKIN1,PCDH19,WDR35,OSBPL8,ARHGAP20,ALK,AMPD2,CDC42BPA,LRCH2,PKP4,APAF1,APC,TNRC6C,SEMA4G,CADPS,STK33,TMEM108,EIF4G3,RNF182,ATP6V1G2,ATP6V0A1,MYOM1,RIPK1,ADAM15,ADGRB2,ADGRB3,SEC11C,RGS9,BCS1L,SGCE,IL33,CA4,CALB1,THSD7A,CALM1,PTBP2,CH25H,CBR1,CCK,CD86,SEPT7,CDH2,LRRFIP1,EPS15L1,CLTB,FAM19A5,HECTD1,FHL5,FAM149A,AKAP6,ABI3BP,ZNF521,SLC35F1,CLOCK,CS,IPCEF1,KIAA0040,UBXN2A,CTH,FAM131B,KIAA0408,ZFYVE16,PABPC5,ARMCX4,SPATA2,YTHDC1,SV2B,SPOCK3,WDR20,DOCK2,DMTF1,ABCC5,E2F5,EDN1,PHC2,PHF20L1,EGFR,MRO,IRAK4,STARD3NL,DENND4A,VPS26C,TLR7,EZH1,F5,ARMCX1,CLVS1,ABCA8,TBC1D16,PPP1R1B,MED12L,FLT1,EFCAB2,JKAMP,ATP6V1H,CELF1,CGREF1,MPP6,MEGF10,HRASLS5,DENND2A,IQGAP2,CPLX2,ALDH1L1,SULT1C4,MSTN,ADAM28,MALT1,RNPS1,TOX3,GLUL,ZNF638,RAB40B,GNAL,FERMT2,GPD2,PCLO,GRIA2,GRIN2D,CIT,CLASRP,ZBTB49,PSIP1,IDH3A,ZNF546,KIAA1755,SLC35G1,METTL21A,KCNB1,KCNJ16,KIT,KTN1,PAXBP1,NCOA7,LSS,MAP4,MARK1,MAT2A,MATN2,MATN3,CHIC1,MEF2C,MEIS1,MEIS2,MIA2,POC1B,AFF1,AFDN,XRRA1,HS6ST3,MXI1,NF1,SLC11A2,NRCAM,NTRK3,OXTR,P2RY1,TREM2,CDK18,ENPP2,FAM98B,NALCN,PIK3C2A,PLCL1,PLXNB1,PURG,PRIMPOL,ANKRD16,PMP22,PSAT1,ING3,PPARA,PPP3CA,RASGEF1B,MAPK4,MAPK9,HYDIN,DIRAS2,PRODH,PRPSAP2,SAMD9,BCAS3,QRICH1,BDNF-AS,PTPRB,PTPRE,CASTOR1,NKAIN1,PPP2R3C,TMEM255A,FAT4,ZNF493,REV3L,RFX3,RGS3,RGS4,PBRM1,ZFHX4,RNH1,EXD2,CCDC102B,RPL15,FAM161B,MEG3,CLIP1,RYR3,FAM192A,AP1AR,SEMA6D,ATXN2,PRCD,SCP2,PPM1E,FERMT1,FBXO11,DZIP1,SEPHS1,SLC8A1,INTS9,DOP1A,PDZD2,BDP1,MYCBP2,KDM4C,IQSEC2,RBM26,NFASC,CLASP2,POGZ,SEPT8,DIP2A,ADHFE1,KANK1,SEPT3,NSFL1C,SYT1,ALG1,IQCE,TCF4,TRIM2,PCDHGA11,DOCK9,SIK3,DNAH7,THRA,ERCC6L2,FAM124A,PRRT1,TP53BP2,TPM1,SYNPO2,PPIL6,ANKRD20A2,TTTY15,TTC3,OSBP2,FLRT2,PLEKHH2,LMF1,GUSBP1,XRCC4,ZNF708,ZNF540,TCEAL7,EML6,ZFAND5,EMSY,SLC38A1,LINC02210,ADAMTS9,PDSS2,JMJD1C,RNF170,MSRB3,SNX14,FRMD6,NETO1" MicroRNA hsa-miR-302e:mirSVR_lowEffct hsa-miR-302e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-100 1.21E-96 3.67E-99 3.38E-98 287 1817 "KCNH8,ABR,NCKAP5,ADCY5,ADCY6,ADD1,ESYT2,OSBPL8,HFM1,C1QTNF3,SPARCL1,SRPX,ARHGAP20,SYT13,AMPD2,AMPD3,SEMA7A,CCDC146,APC,PPP4R4,ARSE,CDK13,INSYN2B,ATP1B3,ATP2B2,LDHD,DST,SYNJ2,ARHGEF7,AP1M1,C5,GPC2,MYRF,CALM1,PTBP2,PRC1,DCLK1,LOC730101,DLGAP2,TIGD7,CCPG1,B4GALT6,PPT2,ARMC8,SUMF2,LETMD1,SLC4A8,AHCTF1,ZNF521,FAM171B,C2CD2,GDA,ABCG1,CSF1,RGS6,CSF2RA,CNTNAP2,FAM169A,PHF14,DCAF4,RUBCN,CCDC144A,DCAF8,HDAC4,ZFYVE16,RASSF2,TMEM170A,AIF1L,YTHDC1,HEPH,MFAP3L,FBXL5,KIAA0319,PLPPR4,WDR20,GRIN3A,DNM1,USP3,CD99L2,DPYSL2,MAMLD1,DNAJB6,DNM1L,KRBA2,KLHL5,TMTC1,PHF20L1,SUGP2,MBNL2,PAN3,RCAN2,SLC43A2,CDKL3,ETV1,CD320,EZH1,F5,ACSL4,TAOK3,PRMT5,FECH,FER,FGFR1,FOXF2,FOXO3,SEMA4D,FLT1,C2orf88,NBEA,ZBED3,SPECC1,PDLIM5,ST6GALNAC3,GALNT15,DENND2A,GALC,ERAP1,INPP5K,GCNT2,PCDH17,MALT1,TOX3,LUZP2,DCLK2,GPD1,PRUNE2,TDRKH,GRIA2,RNF165,ZBTB49,BVES,AP4S1,RASSF8,HAS2,ZHX1,FRMD3,MIER3,HLF,HMGCL,HNF4G,HNMT,EID2B,IL6ST,ITPKB,METTL21A,KHK,KIT,PIK3AP1,MAN2A2,MAP4,MBP,CHIC1,MEF2C,MEIS1,KCTD6,MKLN1,XRRA1,THYN1,N6AMT1,MXI1,RTL5,ZNF862,MYT1,SFR1,ALDH1L2,NFYA,NOVA1,PCBP3,TBC1D25,GPR137C,CNTN3,PRTG,PDE4D,GPR85,OLA1,NLGN3,NALCN,FAM218A,PKD1,ZFYVE21,TMEM38A,GPSM2,PLCB2,EPB41L4B,POU6F1,PPM1B,PPP2R5E,KANSL1,PKIA,MAPK9,HYDIN,GDPD1,PIGG,PTK2,PTPRG,TMEM231,QDPR,RAP1GDS1,RASGRF1,RASGRF2,RBBP6,ZDHHC14,PRRT2,PRIMA1,SLC25A36,NUDT11,PBRM1,LGI2,SETD5,ALG9,CCDC25,RORB,MAP6D1,PTGR2,MEG3,HSD11B1L,RTN1,FNIP1,SMPD3,SUPT20H,HSPA4L,ZFP30,SLC6A11,CCDC88A,SLC11A1,BTBD7,ABTB1,SMARCD3,MBD5,KIF13A,SNRPN,TMCC1,USP33,PDZD2,TRERF1,BDP1,TEX2,IQSEC2,PBLD,ERBIN,CEP68,DIP2A,ADHFE1,SEPT3,SYT1,COBL,ADGRL3,AGTPBP1,ATMIN,ZFP90,TRIM2,SZT2,SYNE1,FAM189A1,PCDHB4,TNS2,PMS2CL,GPR161,GALNT17,RIMBP2,R3HDM1,TPM2,NR2C2,SYNPO2,METTL3,UBE3A,CCDC14,PCDH20,ZNF711,TRIM9,FSTL5,ZSCAN26,DPYSL5,UPF3A,EMSY,MFF,ADAMTS9,HPS4,VPS35L,WNK2,PARP11,PDSS2,EPM2A,JMJD1C,RNF170,NETO2,ST8SIA2" MicroRNA hsa-miR-505:mirSVR_lowEffct hsa-miR-505:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-100 1.33E-96 4.01E-99 3.69E-98 278 1708 "SYN3,PTCHD1,BEND6,OSBPL8,TXNDC16,GPRASP2,MAP4K3,APBB2,USP37,ARNTL,STK33,TMEM108,RNF182,LINC00847,SEC11C,SYNJ2,ARHGEF7,CACNB4,CALM1,KALRN,HAP1,PTBP2,CAST,ZNF501,KRIT1,NUMBL,CNOT8,TAOK2,NDST3,ABCG2,AKAP7,ARMC8,SLC4A8,COX4I1,AHCTF1,RBM39,CRY2,LRIG1,SOCS5,ERC2,PNPLA8,KIAA0408,GPRASP1,ARHGAP32,ARHGAP24,EARS2,ZNF337,KIAA0586,SPOCK2,GIT2,JAKMIP2,KIAA0753,GSDME,RHOBTB1,SACS,SV2B,CHRDL1,NR1D2,SLC12A6,DNM1L,E2F6,EDNRA,HIPK3,MRO,MBNL2,TENM1,ELN,CALCRL,DCTN4,RABEPK,DENND4A,CEP85L,SPEG,PIPOX,DNAJC27,KATNAL1,EYA1,FAM198B,ACSL4,FKTN,KAT8,GORAB,SEC24B,OLFM1,TMEM164,RGPD5,FOXO3,TRMO,UFM1,CAMKK2,KHDRBS3,ST6GALNAC3,STAU2,DOT1L,RAPGEF6,C15orf41,GATM,CYP46A1,NFU1,GHR,RUNDC3A,TXNL4A,KDM2B,GNAO1,ZNF782,GPT2,PRUNE2,GPER1,PCLO,GRB10,DIDO1,GRM8,FAM19A2,COQ10A,ZBTB49,GUCY1B1,ATOH8,ZHX1,FRMD3,SYNPO,HNMT,CFAP126,HSF2,RBPJ,INSM1,NME9,SLC35G1,KCNJ16,GATD1,STXBP5,LAMP2,PIK3AP1,MAP4,LYPLAL1,AQP11,MATN2,MBP,NEXMIF,NEFM,NEK1,NF1,CNOT4,NOVA2,NRCAM,OCRL,OPA1,OXTR,P2RX7,PCDH8,PDE4B,GPR85,PFKFB4,NLGN3,CCSER2,PLCL1,PURG,TRHDE,STRN3,RETREG2,FA2H,PPARA,CCDC144B,PPP2R5E,PRKCB,WBP1L,SNRK,TMEM260,PTPRE,PTPRG,TTC13,TUG1,USP47,ACSS3,RAD17,OXR1,ZDHHC14,REV3L,GTDC1,RFX3,ZDHHC4,PBRM1,LGI2,CCDC82,ZNF532,ARMC5,ROBO1,SPIN3,ZNF671,TCP11L1,PTGR2,ATAT1,NCBP3,SEMA6D,ATXN2,GALNT10,FOXRED1,SGK1,FAM102A,WDR37,KANSL3,SEPHS1,CCDC88A,BTBD7,ATF7IP,EPC1,COA1,RCOR3,IFT122,LIMCH1,FAM126B,TRERF1,BDP1,TSNAXIP1,ZSWIM8,NFASC,PBLD,TROVE2,ITPRID2,SAMSN1,ZC4H2,MPRIP,ELOVL4,SEPT8,TTBK2,NSFL1C,SYNE2,SYPL1,COBL,DNMBP,TAL1,ADGRL3,AGTPBP1,DMXL2,SATB2,ZFP90,ZEB1,TRIM2,SZT2,FAM189A1,SIK3,C18orf54,ARL10,HEY1,R3HDM1,CABIN1,TP53BP1,C9orf85,DOK6,AMACR,TRPS1,TTTY15,FAM155A,ZNF709,CCDC14,VLDLR,ZIC1,ZIC2,ZNF45,ZNF74,REEP1,TMEM237,ANKS1B,PCBP1-AS1,SMARCAD1,EMSY,CADM2,SLC38A1,RNF103,PARP11,EPM2A,DOCK8,ST7,JMJD1C,NLRP3,RNF170,MSRB3,RNF146,CPNE4" MicroRNA hsa-miR-935:mirSVR_lowEffct hsa-miR-935:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.70E-100 2.07E-96 6.23E-99 5.74E-98 276 1687 "ABR,ADCY6,ADD2,ESYT2,BEND6,AP2A2,HECW2,KCTD16,NME5,KIAA1324,SORCS2,WDR35,TXNDC16,HFM1,ALCAM,FAM135A,PITPNM2,LRCH2,DDO,ARNTL,ZBTB10,LINC00847,SEC11C,BCHE,CFLAR,KSR1,SCAPER,WASF1,CA8,CA12,CALB1,SLC25A14,VXN,CAST,LRBA,CLGN,CACNA2D2,TAOK2,RAB28,QKI,MAP4K4,CNR1,CNTFR,AKAP6,ZFP28,SEC31B,RNF14,CS,ARHGEF10,VCAN,PHACTR3,CTH,PUM1,RUBCN,BOC,DOCK4,ARHGAP32,GAPVD1,RIPOR2,HDAC4,LONRF1,MATR3,KCTD8,DGKB,IP6K1,PABPC5,BRINP1,AIF1L,GIT2,PITPNC1,ELMSAN1,ZBTB24,B3GAT3,POM121,RHOBTB1,SV2B,SPOCK3,WDR20,DMTF1,CASP8AP2,DPP6,RCAN1,ECM2,E2F5,EDN1,ANKRD46,HIPK3,HEYL,FRY,APH1A,KMT5B,EGR3,EIF5,ELN,PAN3,EIF1,ACSL4,TAOK3,FCGR1A,SEC24B,MED12L,FGF13,FGF14,SUCO,SEC23B,SYNCRIP,FLT1,NBEA,TMEM107,SMC2,PDLIM5,FAM49B,STAMBP,GALNT15,GAD1,MSTN,DBF4,KDM2B,FERMT2,LILRB4,GPD2,PCLO,ATE1,PRDM5,MIER3,ELOVL5,SHISA6,FAM95B1,SOWAHA,NKD1,INSM1,SLC35G1,KIF5A,KIT,LIFR,MATN3,MBD1,MBP,MID1,XRRA1,GIT1,COMMD5,THYN1,MYO7A,ZNF862,NFE2L2,DNHD1,P2RX7,DPY19L2P2,ENPP2,GPR85,PFKFB2,PFKFB3,OLA1,SERPINI1,NLE1,PMP22,STRN3,LRP12,MINDY2,PPM1B,PRKACB,CEP41,MAPK4,MAPK9,MAPK10,APTX,SNRK,BDNF-AS,STK32A,C1orf109,PEX2,PPP2R3C,FAT4,NWD1,KHDRBS2,REV3L,ERI2,FIGN,SLC25A36,PBRM1,TMLHE,ALG9,PNMA8A,ROBO1,SPIN3,MCMBP,ATP8B4,ADAL,CLIP1,ZNF568,CCDC112,AP1AR,SEMA6D,SATB1,PEAR1,SUPT20H,AMBRA1,NLGN1,WDR37,SEPHS1,RADIL,BTBD7,TET1,CPEB4,TTC17,IFT122,SNAP25,TRERF1,FNBP1,KDM3A,SP4,ZNF423,MCF2L2,PBLD,ITPRID2,SSTR2,SS18,SSPO,NXT2,ST5,ZSCAN29,SEPT8,NECAB1,VPS13A,ANKRD28,ADGRL3,AGTPBP1,SATB2,TCF12,SZT2,SYNE1,DOCK9,SLC35G2,FRYL,PMS2CL,SLC44A1,MTMR14,HEY1,NR2E1,ERCC6L2,TPM1,WBP2,CHST5,RGMB,SYNPO2,STXBP4,TRPS1,DCBLD1,EIF4ENIF1,VIPR2,VSNL1,P2RY12,PCDH20,ZIC2,ZNF711,AGMO,TMEM237,EML6,ANKS1B,ZFAND5,SMARCAD1,MAP3K12,SLC38A1,TMEM178A,EPM2A,FAM13C,AMN1,DOCK8,UBE3B,JMJD1C,NHSL1,ZDHHC20,IFT88,SOCS4,GAN" MicroRNA hsa-miR-2052:mirSVR_highEffct hsa-miR-2052:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.10E-100 2.29E-96 6.89E-99 6.34E-98 266 1569 "KCNH8,ASIC1,KDM5D,PSMG3-AS1,ADD2,KIAA1211,PTCHD1,BEND6,DPY19L2P4,BBOX1,GPRASP2,AMPH,BIN1,OGT,DPP10,PHF12,APAF1,TNRC6C,ZFYVE28,CADPS,MARCH3,EIF4G3,DPY19L3,BACH1,BCHE,PROM1,SYNJ1,SYNJ2,JAZF1,CALM1,PTBP2,ISPD,CLDN10,CDH2,CLGN,UBE2L6,CFL2,RCBTB2,SOCS6,MS4A7,RAB33A,NRXN3,CLCN3,QKI,IGLON5,ARHGEF6,AKAP6,SLC4A8,ZFP28,SLC35F1,CPS1,PREPL,CSF2RA,ARHGEF10,CSNK1G3,SOCS5,CNTNAP2,FAM169A,GREB1,CYBB,DOCK4,HDAC9,ARHGAP32,RIPOR2,LONRF1,TM9SF4,JAKMIP2,RHOBTB1,CHRDL1,EBF1,EDN1,EDNRA,EDNRB,ANKRD46,YAF2,CELSR3,FAM13A,PHF20L1,SUGP2,KMT5B,DCTN4,RCAN2,ENPP6,CDKL3,DNAJC27,F5,ABCA8,TMEM132C,GORAB,SLC9B2,FER,SUCO,HPCAL4,SYNCRIP,C2orf88,SMC2,APOPT1,PDLIM5,DISC1,IGSF5,TUBGCP4,SULT1C4,AHDC1,ADAM28,PPARGC1A,ZNF638,KIAA1958,MAP7D2,ZNF782,FERMT2,LNX1,GPD2,HLF,ELOVL5,HMGCL,LRRC75A,CELF5,JAK2,KCND2,KCNN2,LAMA2,LAMP2,LIG4,HECTD2,ZNF667-AS1,MAT2A,MBNL1,MBP,TM6SF1,LRP1B,SRSF12,KCTD6,AFDN,MMP16,NCAM2,SFR1,NEFM,NNAT,SLC11A2,NTRK2,SETD4,IGSF11,OCRL,OPA1,PCSK1,PDCD2,PFKFB2,PIK3R1,ZNF655,SNX10,MTRF1L,STRN3,TATDN3,PPP3CC,PRKACB,PRKCB,GRAMD1C,HYDIN,DIRAS2,VPS13C,CNTLN,PTCH1,BDNF-AS,TMEM260,EML5,PEX2,TMEM255A,SH3TC2,RAP1GDS1,ZNF493,RDX,ERI2,FIGN,RFX2,RFX3,UBR7,PBRM1,RNASEL,CCDC82,CARF,GSTCD,ROBO1,FBXW7,MCMBP,ATP8B4,KCNIP3,CLIP1,RTN1,SALL1,SEMA6D,ATXN7,FNIP1,SMPD3,PEAR1,TRA2B,CHD9,FBXO11,PPP4R3A,ATF7IP,ZKSCAN3,ANKRD36,LIMCH1,ZNF415,DOK5,SP4,GLT8D1,UHRF1BP1L,KDM4C,RBM26,SPART,ATP10B,SEPT8,TTBK2,KANK1,NECAB1,SYNE2,SYT1,MCF2L,FAM208A,TBCEL,ATMIN,TCEA1,SATB2,TRIM2,CLASP1,PCDHGA11,SYNE1,SLC19A3,PUM2,GPRIN3,SIK3,ZFPM2,SLC44A1,TIAM1,MTMR14,BHLHB9,NR2E1,TMPO,R3HDM1,CSMD1,PARD3,KAT6B,NPL,C9orf85,FAM155A,UBE3A,USP1,TBC1D15,CLDND1,KCNT2,CRB2,TMEM237,EML6,ANKS1B,STOX2,NAV3,KCNAB1,FIP1L1,FAM13C,AMN1,CASC15,TIGD6,KLHDC1,FXR1,FRMD6,IFT88" MicroRNA hsa-miR-4254:mirSVR_lowEffct hsa-miR-4254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.15E-100 2.32E-96 6.95E-99 6.40E-98 298 1959 "SYN3,ACADM,KLHL32,ADD1,ADORA1,ADORA2A,KIAA1211,ESYT2,MTUS1,RTL9,C1QTNF1,SPOP,ARHGAP20,BBOX1,ANK2,FGD2,SUGT1P4-STRA6LP-CCDC180,VAT1L,PPFIA3,AQP6,CDK10,SEMA4G,MADD,ARHGDIA,CDK13,ZNF583,SLC2A11,TTLL9,ADGRB1,ADGRB2,NAE1,SCAPER,CASTOR3,AP1M1,CALB1,VXN,RUNX1T1,CLDN10,KYAT1,USP2,P2RX6,CD86,SYNGR3,ENTPD6,C1orf52,CDC25B,ARHGAP33,LRRFIP1,CCPG1,CACNA2D2,TAOK2,NRXN3,DGCR9,CLTB,CNR1,PCYT1B,ARMC8,FAM149A,WHRN,CABP1,AHCTF1,SMARCAL1,SLC35F1,CPS1,CLOCK,RNF14,ANKRD44,CLIP3,CS,CSF1,CSF1R,SEC24C,LRIG1,OSBPL3,CSNK1G3,SUSD5,IPCEF1,PDE4DIP,PUM1,GPSM1,RIPOR2,ARHGAP24,RASSF2,DAPK1,B3GAT3,RUSC2,DDX46,POM121,TMCC2,ZNF582-AS1,GRIN3A,DNM1,DNAH9,DOCK2,DMTF1,DRP2,DTNA,ABCC5,E2F5,WDPCP,ANKRD46,HIPK3,TMTC1,CELSR3,FAM13A,APH1A,EGFR,RASA4,ELN,GPHN,NCALD,MRPL37,APC2,RASL12,SIRPB1,EXTL2,CLVS1,PPP1R1B,ZNF589,OLFM1,FGF11,FGF13,HPCAL4,SYNCRIP,ZBED3,TRIM16,ZNF605,MPP6,GALNT15,GABRG2,SRRM4,LRRC37A6P,ALDH1L1,SRCAP,CYP46A1,GFER,USP19,TTBK1,CRCP,GLI2,TOX3,ZNF638,RAB40B,GNAO1,GPD1,SPACA9,ADAMTS13,AP4S1,LINGO1,RNFT2,GUCY1B1,MAP4K5,HAS2,VSIG4,AGBL5,AGFG1,HSF2,CELF5,SMAP1,FAM95B1,RBPJ,TJAP1,IL6ST,GPR62,A1BG-AS1,STXBP5,LAMA2,SYTL4,MAN2A2,MBNL1,SCAMP5,MID1,PPM1L,XRRA1,SAMD5,MSI1,PTOV1,FXYD7,NBL1,SFR1,NEK1,NINJ2,NTRK3,NUCB2,PCSK5,PDE4A,GNG2,NALCN,SEMA5B,FAM218A,TMEM38A,PKM,SMOX,PCDH18,LRP12,SCHIP1,PRKCB,MASP1,WBP1L,PTK2,C1orf109,NKAIN1,STRC,CEP97,FAM66C,RASGRF1,RET,REV3L,RGS12,RIC8B,KLHDC8A,CYB561D1,SNX22,NEK11,MCMBP,SGSM1,MEG3,ABCA11P,KCNIP1,MAPK12,SEMA6D,LRFN5,TNFRSF19,SEC14L1,GALNT10,KIF27,FAM102A,FERMT1,HKDC1,AMBRA1,SLA,WDR47,KANSL3,SLC8A1,SLC12A2,MAST1,SMARCD3,MYH15,IFT122,LIMCH1,MBD5,CMTR2,SNRPN,DOP1A,SP4,TEX2,CDK19,TSPYL2,LHPP,CLSTN2,SSTR1,NXT2,NEK4,SYP,TACR1,MTCL1,EXOC7,ALG1,ADGRL3,SIN3B,SATB2,TRIM2,OBSL1,NSD1,DICER1-AS1,TIAM1,CSMD1,PIK3R5,RASD2,NPL,WBP2,TRO,ZKSCAN5,VAV1,WIPF1,KLC2,ZNF74,NDRG4,TCEAL7,ZBTB38,TMEM237,FSTL5,TMEM198,SLC30A4,HPS4,SEMA3B,GAL3ST3,SLC17A7,FIP1L1,TRIM16L,UBE3B,KAT6A,CASC15,TRAM2-AS1,FRMD6,NETO1,ST8SIA2,FAM198A" MicroRNA hsa-miR-520d-5p:PITA hsa-miR-520d-5p:PITA_TOP PITA 4.18E-100 2.34E-96 6.97E-99 6.41E-98 205 915 "ADD1,USP31,INTS2,MTUS1,OSBPL8,UNC79,EP400,MAP4K3,FAM131A,PPFIA3,MARK4,NCOA1,CCAR2,ATP2B2,DPY19L3,JAZF1,CALM1,CBLN1,C1orf52,LRBA,CDH2,ARHGAP33,CDO1,CCPG1,CACNA2D2,FOXN3,SOCS6,CHN2,NRXN3,QKI,TMEM184B,HECTD1,CNR1,ARMC8,COL4A5,AKAP5,AHCTF1,CNRIP1,CDC42BPB,RBM39,CRHBP,CRMP1,LRRC3B,CSNK1E,OSBPL3,CSNK1G3,APPL1,PUM1,KIAA0408,DOCK4,KIF26A,MATR3,DBN1,SNAP91,DLX1,GRIN3A,DYNC1I1,CDON,CPEB2,ARRDC4,MAMLD1,GOLT1B,EDN3,EDNRA,ANKRD46,KLHL5,CELSR3,MBNL2,COPS4,STARD3NL,PAN3,EPB41,EPB41L2,RCAN2,SLC43A2,PPP1R1B,SEC24B,SUCO,UBE2E3,SYNCRIP,AGAP3,AFF2,NBEA,PDLIM5,CELF1,MPP6,OGA,GABRB3,CPLX2,SESN1,RNPS1,STARD3,GNAO1,GRB10,GRIA2,FAM19A2,LINGO1,ADAMTS6,ZHX1,NEGR1,ITPKB,KCNQ3,KIF2A,KIF5A,MAPT,MBNL1,CHIC1,LRP1B,MEF2C,SCAMP5,MID1,MITF,AFDN,MXI1,MYO6,NEXMIF,ZC3H12B,NFIX,SMIM11A,IGSF11,OPA1,GPR137C,PCDH9,PFKFB3,NLGN3,MINDY2,PPP3CA,PPP5C,CEP41,DIRAS2,PSD,ELOVL2,PTK2,PTN,PTPN13,PTPRD,PTPRE,PTPRO,USP47,FAM184A,RAP1GDS1,RDX,GTDC1,FIGN,SETD5,ATXN2,FNIP1,MRAS,CPEB3,NLGN1,WDR37,PPP4R3A,WDR47,CCDC88A,SLC12A2,CPEB4,PDZRN3,MYO16,PDZD2,SOX11,ZHX3,SP4,RBM26,LMO3,SS18,ERBIN,SEPT8,PRRC2C,TAL1,FBXW11,TBL1X,TCF4,SZT2,PUM2,CRTC1,SIRT1,ZNF106,TIAM1,HEY1,CBX5,ERCC6L2,RIMBP2,KAT6B,TPM1,TRPS1,FLRT2,MTCH1,ZIC1,ZNF711,LYPD6,ZBTB38,SMARCAD1,DNALI1,TMEM178A,NAV3,ITM2C,RGS7BP,FAM13C,FZD3,KAT6A,ADAMTSL3,JMJD1C,MSRB3,NETO2,FAM181A" MicroRNA hsa-miR-524-5p:PITA hsa-miR-524-5p:PITA_TOP PITA 4.18E-100 2.34E-96 6.97E-99 6.41E-98 205 915 "ADD1,USP31,INTS2,MTUS1,OSBPL8,UNC79,EP400,MAP4K3,FAM131A,PPFIA3,MARK4,NCOA1,CCAR2,ATP2B2,DPY19L3,JAZF1,CALM1,CBLN1,C1orf52,LRBA,CDH2,ARHGAP33,CDO1,CCPG1,CACNA2D2,FOXN3,SOCS6,CHN2,NRXN3,QKI,TMEM184B,HECTD1,CNR1,ARMC8,COL4A5,AKAP5,AHCTF1,CNRIP1,CDC42BPB,RBM39,CRHBP,CRMP1,LRRC3B,CSNK1E,OSBPL3,CSNK1G3,APPL1,PUM1,KIAA0408,DOCK4,KIF26A,MATR3,DBN1,SNAP91,DLX1,GRIN3A,DYNC1I1,CDON,CPEB2,ARRDC4,MAMLD1,GOLT1B,EDN3,EDNRA,ANKRD46,KLHL5,CELSR3,MBNL2,COPS4,STARD3NL,PAN3,EPB41,EPB41L2,RCAN2,SLC43A2,PPP1R1B,SEC24B,SUCO,UBE2E3,SYNCRIP,AGAP3,AFF2,NBEA,PDLIM5,CELF1,MPP6,OGA,GABRB3,CPLX2,SESN1,RNPS1,STARD3,GNAO1,GRB10,GRIA2,FAM19A2,LINGO1,ADAMTS6,ZHX1,NEGR1,ITPKB,KCNQ3,KIF2A,KIF5A,MAPT,MBNL1,CHIC1,LRP1B,MEF2C,SCAMP5,MID1,MITF,AFDN,MXI1,MYO6,NEXMIF,ZC3H12B,NFIX,SMIM11A,IGSF11,OPA1,GPR137C,PCDH9,PFKFB3,NLGN3,MINDY2,PPP3CA,PPP5C,CEP41,DIRAS2,PSD,ELOVL2,PTK2,PTN,PTPN13,PTPRD,PTPRE,PTPRO,USP47,FAM184A,RAP1GDS1,RDX,GTDC1,FIGN,SETD5,ATXN2,FNIP1,MRAS,CPEB3,NLGN1,WDR37,PPP4R3A,WDR47,CCDC88A,SLC12A2,CPEB4,PDZRN3,MYO16,PDZD2,SOX11,ZHX3,SP4,RBM26,LMO3,SS18,ERBIN,SEPT8,PRRC2C,TAL1,FBXW11,TBL1X,TCF4,SZT2,PUM2,CRTC1,SIRT1,ZNF106,TIAM1,HEY1,CBX5,ERCC6L2,RIMBP2,KAT6B,TPM1,TRPS1,FLRT2,MTCH1,ZIC1,ZNF711,LYPD6,ZBTB38,SMARCAD1,DNALI1,TMEM178A,NAV3,ITM2C,RGS7BP,FAM13C,FZD3,KAT6A,ADAMTSL3,JMJD1C,MSRB3,NETO2,FAM181A" MicroRNA hsa-miR-196a*:mirSVR_lowEffct hsa-miR-196a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.24E-100 2.37E-96 7.03E-99 6.47E-98 284 1785 "SYS1,ACTN1,GALNT16,BRAP,PWWP2A,PTCHD1,ZNF608,INTS2,KCTD16,NME5,WDR35,AK2,TAOK1,UNC79,CDC42BPA,APAF1,APBA2,CDC14B,RGS20,NUMB,ATP1B3,ATP2B2,RIPK1,MPDZ,SEC11C,CFLAR,CACNA1I,CA4,CACNA1B,CALB1,CALM1,CAMK2B,CCNH,MTMR7,LRBA,SEPT7,CDC25B,NOG,CNOT8,NRXN3,PPT2,TPP1,QKI,RAB26,CNN3,ARHGEF6,ARMC8,ANKRD35,SUMF2,LETMD1,SLC35F1,CRY2,GDA,VAC14-AS1,PDE4DIP,FAM169A,APPL1,PHF14,ZSCAN23,CCDC144A,GPRASP1,MYADM,ARHGAP32,TCAF1,RIPOR2,ARHGAP24,LONRF1,INTS1,MAML1,IP6K1,GIT2,YTHDC1,TMEM130,ZC3H11A,DDX46,GUCD1,WDR20,CPEB2,DMTF1,DPP6,EDNRB,TMTC1,YAF2,MBNL2,KMT5B,RASA4,EIF5,CERCAM,VPS13B,RABEPK,DENND4A,VPS26C,F5,SCML2,FCGRT,STRADA,FER,SPSB4,MEX3B,FLT1,ANKFY1,HVCN1,PDLIM5,KHDRBS3,CELF1,TVP23A,GABRG1,SIGLEC8,MTHFD2,PCDH17,GGT7,CRCP,HPGDS,SPIN1,LOXL3,ADGRA3,FUT10,CCDC184,RNF165,AP4S1,RABL2A,SOX21,FAM107A,GUCY1A1,RASSF8,BACH2,MIER3,HLF,ZDHHC15,NEGR1,DHX35,SHISA6,KIAA1755,INPP5B,SLC35G1,KCNB1,KCNF1,STXBP5,KTN1,STMN1,ZFYVE27,MARK3,MAT2A,MBNL1,MBP,EFHB,KITLG,MMP16,MYO7A,MYO9A,RTL5,NCAM2,ZC3H12B,NEK1,CNOT4,NOVA1,PCBP3,SLC11A2,NTRK2,NTRK3,SETD4,IGSF11,OCRL,CLDN11,P2RX7,TMOD2,PLCL1,MTRF1L,PURG,MBOAT7,EPB41L4B,DRAM2,PPARA,TATDN3,RANBP3L,CNNM2,WBP1L,CNTLN,MTMR10,PTPRG,RIPOR1,PID1,FAM66C,RASGRF1,REV3L,ZFHX4,SETD5,EXD2,ALG9,GSTCD,CYB561D1,NEK11,EPHA10,RPL15,ZC3H14,RTN1,STX1B,TRAPPC13,RMI1,SATB1,ATXN2,ATXN7,CASC3,TRA2B,ZFP30,KIF21A,SH3GL3,FUZ,FHOD3,CNKSR2,DZIP1,KANSL3,SLC6A11,SLC8A1,ARHGEF40,SLC11A1,SLC12A4,BTBD7,EPC1,MAPKBP1,SNRPN,TMCC1,FAM126B,SOX3,BDP1,SP2,ZSWIM8,NMNAT2,PEG10,SPTAN1,NFASC,ITPRID2,SSTR1,ZC4H2,SS18,ERBIN,ZSCAN29,CEP68,ADHFE1,STX1A,COBL,DNMBP,KIAA1107,FBXW11,KLHL4,DMXL2,SLC19A3,NSD1,FRYL,HIF3A,DICER1,ZFPM2,ITGB3BP,ARL10,HEY1,TIMP4,ACTR6,ERCC6L2,C9orf85,WBP2,STXBP4,TRPS1,TTC3,ZKSCAN5,CLHC1,TUBB1,RPRM,UBE2H,XRCC4,MKRN3,ZNF177,POLR3H,FSTL5,TMEM198,SMARCAD1,MEIS3,EMSY,EVI5,STOX2,RNF103,FAM47E,PDSS2,FAM13C,FAM181A" MicroRNA hsa-miR-137:mirSVR_highEffct hsa-miR-137:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.76E-100 2.67E-96 7.89E-99 7.26E-98 271 1629 "KCNH8,ACADM,CLK4,ABHD6,NCKAP5,KDM5D,FMNL2,BEND6,DPY19L2P4,AP2A1,INTS2,MTUS1,NME5,C1QTNF3,ABCD2,PCDH10,UNC79,PARG,SHROOM2,CADPS,MARCH3,ATP2B2,SLC2A11,DPY19L3,ADAM23,TTLL9,ADGRB3,DST,ARHGEF7,CACNA1G,CH25H,MTMR7,DGKI,LRBA,DCLK1,TIGD7,CCPG1,CHN2,NRXN3,QKI,ARMC8,FAM149A,COL4A5,ABI3BP,BAG4,ZNF385A,GDA,RGS6,CSNK1G3,GREB1,RIMS2,KATNAL2,ARHGAP24,HDAC4,ZFYVE16,TBC1D5,MAML1,DAPK1,ELMSAN1,ZNF804A,ZC3H11A,DDX46,RHOBTB1,CHRDL1,NR1D2,CPEB2,RCAN1,DTNA,GOLT1B,E2F6,AASDH,EDIL3,SEZ6L2,EDN1,EDNRB,FRY,PHF20L1,MBNL2,AASS,KCTD3,PLEKHA1,RGS17,CALCRL,RCAN2,SLC43A2,CEP85L,ADGRV1,EZH1,FAM198B,FCGR1A,FCGR1B,FER,SCARA3,SYNCRIP,AGAP3,NBEA,TPK1,ATP2C1,ZNF605,MEGF11,MEGF10,GABRB3,WASHC2A,GPR162,PPARGC1A,MALT1,RAB30,ZNF638,LUZP2,ADGRA3,GPD2,GPR34,ATP2B1-AS1,RNF165,RABL2A,SOX21,RNFT2,MAP4K5,RASSF8,HLF,TCEAL6,RBPJ,SCIN,KCND1,KCND2,KIT,LAMP2,MAP2,MARK1,LYPLAL1,LRP1B,MEST,MITF,MKLN1,MSI1,ADAM22,NCAM2,NEFH,NF1,CNOT4,NOVA1,NTRK3,CHAMP1,LOC100128398,GPR137C,CNTN3,ETFRF1,PCSK5,PDE1B,GPR85,RETREG1,XRN1,PCDH18,STRN3,LRP12,ING3,LRRN3,PPP2R5E,PRKACB,DIRAS2,GDPD1,WBP1L,WDR25,CNTLN,ELOVL2,PTN,TMEM260,PTPRG,NKAIN1,STRC,ZNF844,RAD51D,ZNF793,OXR1,MSANTD2,RDX,ZMAT4,MORC4,GTDC1,UBR7,RGS3,RNASEL,TMLHE,PCMTD2,FBXW7,ATP8B4,LRRK2,ABCA11P,SUPT20H,CHD9,PPP4R3A,SLC6A8,SLC8A1,SLC12A2,ATF7IP,GKAP1,LIMCH1,FAM126B,USP33,BDP1,NMNAT2,ZC3H13,RBM26,TROVE2,SS18,ERBIN,NXT2,NEK4,DIP2A,VPS13A,PLCB1,SYT1,COBL,ANKRD12,CAMTA1,KLHL4,SATB2,RPGRIP1L,TCF12,PCDHGA11,SYNE1,PCDHB9,PCDHB7,TEK,ZFPM2,ITGB3BP,AP4E1,AKTIP,TLR4,TMPO,PRRT1,TNS1,C9orf85,RGMB,PDSS1,TSN,TUBB1,UBE2H,SLC35A4,OSBP2,USP1,BCL2L13,VSNL1,WIPF1,WNT7A,RICTOR,KCNT2,TRIM9,MKRN3,EML6,ZSCAN26,ANKS1B,SH3GLB2,LAMP5,SLC30A4,EMSY,CIAPIN1,PLSCR4,RGS7BP,FZD3,DOCK8,RTN4,HNRNPA3,PHTF2,TIGD6,RNF170,MSRB3,FRMD6,IFT88,DPF3,PRRT4" MicroRNA hsa-miR-618:mirSVR_lowEffct hsa-miR-618:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-100 2.87E-96 8.47E-99 7.80E-98 268 1594 "NCKAP5,SYS1,GALNT16,GALNT13,RNF157,ADD2,PLEKHH1,PWWP2A,RNF150,AP2A2,TAOK1,MARCH4,UNC79,ZFAT,CDC42BPA,LRCH2,EP400,MAP4K3,SUGT1P4-STRA6LP-CCDC180,DDO,VAT1L,LINC00173,MARK4,ZSCAN18,CHRD,EIF4G3,ATP1B3,STX16,RNF182,RIPK1,DOCK11,BACH1,BARD1,BCL7A,SCAPER,MTMR3,MTMR2,CA8,KALRN,PTBP2,NFS1,CCNH,CCPG1,CFL2,NRXN3,QKI,MAP4K4,AKAP7,IQCK,AKAP6,COL11A2,AKAP5,RCHY1,CLOCK,PREPL,CREM,HAPLN1,SNCAIP,ARHGEF10,SOCS5,CST3,APPL1,UBXN2A,PHF14,GREB1,RIMS2,CCDC144A,BOC,GAPVD1,ARHGAP24,DGKB,DAPK1,DNAL1,C2CD2L,POM121,SV2B,WDR20,GRIN3A,RPS6KL1,DNM1L,EDN1,TMTC1,PHF20L1,IRAK4,TNK2,PCOLCE2,SH3YL1,SCML2,FCGRT,ZNF589,MED12L,OLFM1,AMOTL2,SCARA3,MEX3B,HPCAL4,FLT1,UFM1,TRIM16,CAMKK2,MEGF10,GAD1,ERAP1,TMEM8B,MTHFD2,LRRC37A6P,SULT1C4,CYP46A1,ADAM28,PCDH17,PPARGC1A,MALT1,TOX3,ZNF638,KDM2B,LUZP2,KCNMB4,DCLK2,TMEM121B,GRIA2,GRIN2C,GUCY1B1,RASSF8,PADI2,ZHX1,FRMD3,ARHGAP36,ELOVL5,GABARAPL2,MSL1,SCIN,IL6ST,INPP5B,INSM1,LRRTM1,NME9,CDH20,KCNJ16,KTN1,LAMP2,MBD1,TM6SF1,MEIS2,MID1,XRRA1,SAMD5,MSR1,HS6ST3,NACA,TCEAL5,NFIX,SLC11A2,PCSK1,PDE4D,DUSP26,ZNF655,EPDR1,MAPK9,DIRAS2,VPS13C,SNRK,PTCH1,TMEM260,STK32A,PTPRG,RIPOR1,ZSCAN2,TUG1,STRC,TMEM255A,USP47,FAM66C,ENOX1,ZNF493,RBBP8,GTDC1,RFX3,PRIMA1,CCDC82,ROBO2,YY1AP1,CCDC102B,ARMH4,GLDN,ADAL,LRRK2,NCBP3,ZNF331,TRAPPC13,SATB1,CSRNP3,ATXN7,TRA2B,FRMPD1,CHD9,DZIP1,PREX2,KDM4D,TET1,EPC1,RCOR3,IFT122,ANKRD36,LIMCH1,CABCOCO1,LMBRD1,SNRPN,TMCC1,NMNAT2,TSPYL2,NFASC,ATP10B,ADAMTS17,COBL,ANKRD28,TACR1,ANKRD12,MTCL1,MCF2L,PDLIM2,ADGRL3,KLHL4,CUX2,ZEB1,RPGRIP1L,TCF12,PHF24,PUM2,USP32P1,TNS2,FRYL,FAM200B,DICER1,ZFPM2,GALNT17,R3HDM1,CSMD1,KAT6B,RGMB,TRO,STXBP4,TSC1,CLEC2L,FLRT2,ZNF709,RICTOR,CFAP298,ZNF24,MKRN3,ZNF154,EML6,ZSCAN26,ANKS1B,SPIRE1,UPF3A,EVI5,ADAMTS9,PPP1R3F,FAM47E,EPM2A,RGS7BP,DNAH10,FAM13C,SMIM8,PHTF2,ADAMTSL3,FRMD6,FAM198A" MicroRNA hsa-miR-32:mirSVR_lowEffct hsa-miR-32:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-100 2.90E-96 8.52E-99 7.84E-98 286 1811 "VWA5B2,AS3MT,ELFN2,CCDC85A,ADD2,AXIN2,PWWP2A,BEND6,MTA3,INTS2,HACE1,OSBPL6,OSBPL8,AK2,PCDH10,UNC79,AMPH,LRCH2,ANK2,PKP4,APBB2,MAGEE2,DDO,LGR5,PPP4R4,CASK,RGS20,CDK13,ZBTB10,SLC4A4,ATP1B3,N4BP2L1,DOCK11,BACH1,MIR9-3HG,ZNF599,FUBP1,CERS5,SLC16A4,DCLK1,DLGAP2,CLGN,PLAA,AKAP7,PCYT1B,ARMC8,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,SEC31B,AKAP12,AATK,RGS6,ARHGEF10,SIPA1L1,PHACTR3,PLXNA4,DZIP3,RIMS2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,NR1D2,DPYSL2,MAMLD1,EDIL3,FAM13A,PHF20L1,RASA4,EIF4G2,TENM1,STARD3NL,CALCRL,EIF1,EMX2,RCAN2,STX2,SRRM1,ERBB4,MRPL37,DNAJC27,EYA1,CLVS1,NSRP1,SCML2,DLC1,RACK1,ST3GAL6,FKTN,FER,MED12L,FGF1,FGF13,PRKAG2,UBE2E3,MEX3B,SYNCRIP,FOXO3,SEMA4D,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF10,GABBR1,MTHFD2,LRRC37A6P,KIAA1841,GATM,CRCP,TCERG1,DBF4,PRRC2B,FUT10,STON1,GRM8,GSTT2,SOX21,GUCY1B1,IRAK3,HMGCR,AGFG1,LRRC75A,EID2B,SCIN,INSM1,JAK2,METTL21A,KCND2,IPO5,STXBP5,LIFR,PAXBP1,HECTD2,NCOA7,PACRG,MAP4,MARK3,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MEST,AFF1,MMP16,MYH3,NEXMIF,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,GLIPR1L2,PCDH8,PCDH9,PCSK5,PFKFB4,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,FA2H,PPARA,PPP3CC,RANBP3L,PRKAB2,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,ANKHD1,PTPRG,PEX2,STRC,MARCH1,USP47,RAD51D,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,SLC25A36,ZFHX4,EXD2,ELP2,STK32B,LRRK2,RPS20,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,ATXN7,SCP2,RASA3,SGK1,FERMT1,SHC4,FBXO11,SYBU,FAM81A,SEPHS1,NAPB,ATF7IP,SMARCC2,LMBRD1,SNRPN,DOK5,HECW1,SPP1,ZNF423,MCF2L2,RBM26,ZC4H2,SS18,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,KLHL4,TCF4,SIN3B,DMXL2,NAT16,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TLR4,CSMD1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,PLEKHH2,RICTOR,XRCC4,ZNF28,ELFN1,NDRG4,SPHK2,REEP1,SMARCAD1,MEIS3,ZXDA,TMEM178A,FZD3,KAT6A,FBXO36,JMJD1C,MSRB3,NHSL1,NETO1,SENP7" MicroRNA hsa-miR-25:mirSVR_lowEffct hsa-miR-25:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.44E-100 3.04E-96 8.92E-99 8.22E-98 280 1738 "VWA5B2,AS3MT,ELFN2,CCDC85A,PWWP2A,BEND6,MTA3,HACE1,OSBPL8,AK2,PCDH10,UNC79,AMPH,LRCH2,ANK2,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB2,MAGEE2,DDO,PPP4R4,CASK,RGS20,CDK13,ZBTB10,NCOA1,TMEM108,SLC4A4,ATP1B3,BACH1,FUBP1,SLC16A4,L3MBTL4,DLGAP2,CLGN,PLAA,NGEF,MAP4K4,LY86,AKAP7,PCYT1B,ARMC8,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,WDR20,NR1D2,MAMLD1,ABCC5,EDIL3,FAM13A,PHF20L1,EIF4G2,TENM1,STARD3NL,EIF1,EMX2,ERBB4,MRPL37,DNAJC27,CLVS1,SCML2,DLC1,RACK1,ST3GAL6,FKTN,GORAB,FER,MED12L,FGF1,FGF13,PRKAG2,SCARA3,MEX3B,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF10,GABBR1,MTHFD2,LRRC37A6P,KIAA1841,GATM,ADAM28,CRCP,DBF4,ZNF638,DCLK2,PRRC2B,FUT10,GRM8,GSTT2,SOX21,GUCY1B1,ZHX1,HMGCR,LRRC75A,EID2B,SCIN,INSM1,JAK2,METTL21A,KCND2,IPO5,STXBP5,PAXBP1,HECTD2,NCOA7,PACRG,MAP4,MARK3,TM6SF1,MEF2C,MEIS1,AFF1,MMP16,MYH3,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PFKFB4,PIK3C2A,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,PPARA,PPP2R5E,NKAIN4,RANBP3L,PRKAB2,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,PTPRG,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,SLC25A36,ZFHX4,EXD2,C12orf49,ELP2,STK32B,LRRK2,RPS20,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,ATXN7,RASA3,SGK1,FERMT1,SHC4,SYBU,FAM81A,SEPHS1,ATF7IP,SMARCC2,LMBRD1,SNRPN,SOX11,DOK5,NMNAT2,HECW1,ZNF423,TSPYL2,MCF2L2,RBM26,ATP10B,ZC4H2,SS18,ERBIN,ZSCAN29,SEPT8,DIP2A,STXBP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,KLHL4,ATMIN,TCF4,DMXL2,ZEB1,NAT16,GPRIN3,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TLR4,TPM1,METTL3,PDSS1,STXBP4,TSC1,SSBP2,PLEKHH2,XRCC4,ZNF28,TRIM9,ELFN1,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,EPM2A,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,FAM198A,SPATA13,SENP7" MicroRNA hsa-miR-136:mirSVR_highEffct hsa-miR-136:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.90E-100 3.86E-96 1.13E-98 1.04E-97 259 1491 "AS3MT,ADCY6,CCDC85A,ADD1,PWWP2A,ZNF608,INTS2,RTL9,WDR35,CC2D2A,SPARCL1,ALCAM,AMPH,LRCH2,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,PPFIA3,ZFYVE28,ARNTL,CADPS,MARCH3,STK33,N4BP2L1,BACH1,RGS11,JAZF1,CACNA1G,CALB1,KALRN,CAMK2G,NFS1,ZNF501,DGKI,LRBA,DLGAP1,CCPG1,CACNA2D2,SRSF11,NDST3,FBXO7,CNTN1,AKAP7,ARMC8,FAM149A,COL4A5,AKAP5,ABI3BP,SEC31B,SH2B1,SNCAIP,RGS6,OSBPL3,SIPA1L1,VCAN,CTH,GREB1,ARHGEF4,KATNAL2,GAPVD1,EARS2,DGKG,IP6K1,C2CD2L,DDX46,ALKBH8,POM121,RHOBTB1,SACS,WDR20,USP3,CPEB2,DMTF1,DTNA,GOLT1B,AASDH,SEMA3D,TMTC1,FSD1L,APH1A,EBI3,MBNL2,COPS4,TUBD1,EPB41,IGSF6,MRVI1,F8,ABCA8,ACSL4,CHST15,ZSCAN30,FDFT1,GORAB,SUCO,FLT1,NELFCD,UFM1,PDLIM5,TPK1,CGREF1,ST6GALNAC3,MEGF10,TRAF3IP2,MTHFD2,GATM,IGSF5,NEU3,GCNT2,SESN1,ADAM28,USP19,GGTA1P,PPARGC1A,LYVE1,TNRC6A,ZNF638,KDM2B,GPT2,STMN2,PLCD4,PRDM5,RNFT2,MIER3,ZDHHC15,SMAP1,ZNF181,ZNF546,ZIC5,IL6ST,ITGAM,SYTL4,NCOA7,MARK1,SRSF12,MID1,AFDN,XRRA1,BLOC1S2,MYT1,NEK1,NF1,CNOT4,NOVA1,NTRK2,DPY19L2P2,PCSK5,CYTL1,SEMA5B,ZNF655,PMP22,STRN3,LRP12,MBOAT7,SH3KBP1,PPP2R5E,MASP1,SNRK,WDR25,PIGG,CNTLN,ELOVL2,TMEM260,PTPN13,PTPRE,PTPRG,TTC13,FAM66C,RAP1GDS1,OXR1,KHDRBS2,TRIM68,GTDC1,RFX3,RGS4,KLHDC8A,CARF,ARMH4,GLDN,LRRK2,RYR3,ZFP2,CASC3,KIF16B,FBXO11,CNKSR2,NUBPL,SLA,BTBD3,SEPHS1,RADIL,ARHGEF40,CCDC88A,SLC12A2,SLC12A4,SLC14A1,NAPB,ATF7IP,RCOR3,TRERF1,BDP1,HECW1,ZNF423,PBLD,POGZ,ZNF302,ZC4H2,NKAIN2,NXT2,NECAB1,SUPT5H,PRRC2C,SYP,SYT1,CAMTA1,ADGRL3,ZEB1,RPGRIP1L,SYNE1,DOCK9,RNF216P1,ITGB3BP,AKTIP,NR2E1,ERCC6L2,KAT6B,NPL,METTL3,TTTY15,UBE2H,UBE3A,PLEKHH2,VLDLR,WIPF1,ZNF781,WRN,ZFP37,ZNF23,MICU3,ZNF28,ZNF32,ZNF138,EML6,SPIRE1,SLC30A4,PRTFDC1,PRDM8,NAV3,KCNAB1,PDSS2,MARCH8,UBE3B,KAT6A,PHTF2,JMJD1C,TRAM2-AS1,MSRB3" MicroRNA hsa-miR-578:mirSVR_highEffct hsa-miR-578:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.12E-100 3.98E-96 1.16E-98 1.07E-97 288 1838 "KCNH8,ACADM,KDM5D,RNF157,PCDH19,KCTD16,HFM1,SPOP,CEP126,ABCD2,ARHGAP20,FAM135A,ZFAT,LRCH2,LCORL,MAP4K3,CDC14B,ARNTL,RGS20,STK33,NUMB,ATP2A2,DPY19L3,TTLL9,MPDZ,SEC11C,NRP2,CFLAR,DST,SYNJ2,CA12,KALRN,PTBP2,CAMK2G,CAST,RUNX1T1,NFS1,ZNF501,LDB2,KRIT1,ZBED1,KCNAB3,MAGI1,RCBTB2,SRSF11,CHN2,NDST3,PLAA,C4orf33,FAM149A,ABI3BP,BAG4,ZFP28,CREM,AKAP12,CRMP1,CSF2RA,ARHGEF10,VCAN,PDE4DIP,UBXN2A,PHF14,PNPLA8,GREB1,ARHGEF4,CYBB,HDAC9,GAPVD1,ZFYVE16,CENPL,LONRF1,TM9SF4,MATR3,KIAA0586,KCTD8,PABPC5,PITPNC1,KIAA0753,PLPPR4,SPOCK3,WDR20,EXOG,GRIN3A,DMD,NR1D2,CPEB2,ABCC5,DNM1L,E2F5,EDN3,HIPK3,KLHL5,OPTN,SUGP2,MRO,EPB41L2,RCAN2,EPHB1,ENPP6,RABEPK,SRRM1,F5,FAM198B,ACSL4,FER,FGF11,FGF12,BAIAP2,SYNCRIP,FLT1,C2orf88,SMC2,APOPT1,AP4B1,ABLIM2,FYB1,TMEM8B,SIGLEC8,ZNF559,LRRC37A6P,GCNT2,MSTN,SESN1,ADAM28,PCDH17,MALT1,BRD8,GLI2,TOX3,MAP7D2,ZNF782,LNX1,WDFY3-AS2,LPAR4,GRIA2,PRDM5,CIT,CLASRP,SOX21,RASSF8,HAS2,UBE2QL1,PADI2,HMGCR,NEGR1,IRF8,LRRCC1,DISP2,SCIN,FAM69A,NME9,ITGAM,KCND2,KCNJ16,STXBP5,HECTD2,NCOA7,MARK1,LYPLAL1,MAT2A,MATN2,MEIS2,KCTD6,MITF,XRRA1,MXI1,NF1,NPTX1,NTRK3,NUCB2,OGG1,GLIPR1L2,CNTN3,PAX6,PDE4D,GNG2,PIK3C2A,RETREG1,NLE1,PLCL1,PCDH18,PRIMPOL,STRN3,SDK2,ING3,SEPT4,PPP3CA,MAPK9,HYDIN,DCHS2,PTCH1,BDNF-AS,PTK2,TMEM260,PTPRE,ACSM5,CEP97,USP47,RAD17,FAT4,RASGRF2,RDX,NUDT11,SETD5,CARF,CCDC25,RORB,MRAP2,NEK11,FBXW7,BAALC,ATP8B4,ABCA11P,ATAT1,RYR3,ZNF331,TNFRSF19,TRA2B,SCAF8,PPM1E,CPEB3,FHOD3,ANKRD6,CPEB4,SMARCA4,OGDHL,MBD5,KIF13A,MYO16,ZBTB43,RBM26,LARP4,TTBK2,RGL1,JMJD6,ARHGEF9,VPS13A,SYPL1,COBL,EXOC7,ADGRL3,TBCEL,ATMIN,CLASP1,DOCK9,PCDHB9,PCDHB3,PUM2,GPRIN3,FRYL,AP4E1,MTMR14,HEY1,ERCC6L2,FAM124A,CSMD1,TRO,CLHC1,SGK3,TUBB1,FLRT2,USP1,CCDC14,WIPF1,ZBTB14,ZNF23,ZNF24,MICU3,KCNT2,TRIM9,AGMO,ZNF74,LYPD6,ZNF138,FSTL5,ZFAND5,UPF3A,PRTFDC1,SLC38A1,VPS35L,WNK2,PDSS2,EPM2A,FZD3,RTN4,TRAM2-AS1,TIGD6,MSRB3" MicroRNA hsa-miR-379*:mirSVR_highEffct hsa-miR-379*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-99 8.15E-96 2.37E-98 2.18E-97 243 1315 "CLK4,NCKAP5,PTCHD1,RTL9,CC2D2A,ALCAM,LRCH2,VAT1L,BCAS1,TNRC6C,ZBTB10,NCOA1,NUMB,TMEM108,SLC4A4,ATP1B3,DPY19L3,SEC11C,AP1M1,SGCE,WASF1,KALRN,MTMR7,CD86,SYNGR3,CDH2,LRRFIP1,LARGE1,MAGI1,DLGAP1,SRSF11,CHN1,NDST3,PLAA,FBXO7,ARMC8,AKAP6,COL4A5,AKAP5,SLC35F1,SEC31B,CLOCK,RBM39,SH2B1,CSNK1G3,PDE4DIP,FAM169A,DZIP3,RIMS2,CCDC144A,CYBB,KATNAL2,LIN54,PABPC5,ELMSAN1,GSDME,SPOCK3,SEC16A,GRIN3A,DMD,DMTF1,RCAN1,ECM2,EDNRB,HIPK3,FCF1,RASGRP1,FSD1L,YAF2,MRO,EIF4G2,TENM1,PLEKHA1,TMEM35A,C8orf37,CALCRL,LRRC17,ENPP6,SRRM1,CEP85L,RRAGB,ABCA8,FAM198B,CHST15,SEC24B,FER,POLR1B,POLK,SUCO,IP6K2,NELFCD,C2orf88,PDLIM5,TPK1,ATP6V1H,GABRG2,RAPGEF6,INPP5K,ARFIP1,PPARGC1A,SPIN1,ZNF638,KIAA1958,KDM2B,HTATSF1,ADGRA3,PSIP1,GUCY1B1,MAP4K5,FRMD3,ATXN2L,AGBL5,MSL1,ZNF678,PAXBP1,HECTD2,MAP4,MBNL1,CHIC1,MEIS1,MEIS2,MITF,MSI1,ADAM22,MYO9A,HNRNPM,IDNK,NEFM,NEK1,DNHD1,NRCAM,GLIPR1L2,CNTN3,SLC10A4,GPR85,GNG2,OLA1,SNX10,RETREG1,PMP22,SCHIP1,EPB41L4B,MINDY2,PPP2R2C,PPP3CA,KANSL1,HYDIN,CNTLN,BDNF-AS,TMEM260,PTPRB,PTPRD,C1orf109,PPP2R3C,PID1,USP47,ACSS3,KHDRBS2,RDX,GTDC1,FIGN,RFX3,SLC25A36,NUDT11,PBRM1,RNASEL,ZFHX4,ZNF532,CARF,RORB,ATP8B4,ADAL,LRRK2,SALL1,SEMA6D,SATB1,SCP2,FNIP1,SUPT20H,SGK1,CHD9,NLGN1,WDR47,KDM4D,SEPHS1,SLC12A2,ATF7IP,ZFP1,SMARCA4,CMTR2,SNRPN,SOX3,SP4,KDM4C,RBM26,ATP10B,TROVE2,NKAIN2,ELOVL4,TTBK2,PHLDB1,SYNE2,VPS13A,SYPL1,MTCL1,CAMTA1,MCF2L,EXOC7,FAM208A,TBCEL,CUX2,ZEB1,RPGRIP1L,SYNE1,PCDHB10,PCDHB6,PUM2,FRYL,PMS2CL,SLC44A1,RGMB,TRO,CLHC1,UBE3A,UGT8,PLEKHH2,WRN,ZNF711,MICU3,KCNT2,MKRN3,ANKS1B,FTSJ1,CADM2,STOX2,RNF103,AMN1,DOCK8,PHTF2,JMJD1C,FXR1,NETO2,NETO1" MicroRNA hsa-miR-558:mirSVR_lowEffct hsa-miR-558:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-99 8.20E-96 2.38E-98 2.19E-97 268 1601 "ABCF1,KLHL32,TMCC3,RNF157,BRAP,ESYT2,PTCHD1,PCDH19,OSBPL6,SPARCL1,FAM135A,ZNF687,PITPNM2,AMPH,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,TNRC6C,ARNTL,ZNF583,SLC2A11,RIPK1,TTLL9,ADGRB3,RGS11,GPR146,ZNF599,SCAPER,MTMR3,MTMR2,CACNA1I,CFAP410,CALB2,CABP7,CAMK2G,RUNX1T1,CBR1,ARHGEF1,DGKI,CLGN,SRSF11,EPS15L1,RAB28,STOML1,FAM19A5,CNTN1,AKAP6,SUMF2,RTTN,CLOCK,PREPL,CSNK1E,OSBPL3,GALNT9,VAC14-AS1,CST3,FAM169A,ERC2,PHF14,RUBCN,CCDC144A,DCAF8,MAML1,IP6K1,DBN1,ARMCX4,YTHDC1,RUSC2,ZC3H11A,TMCC2,WDR20,SEC16A,ZNF582-AS1,GRIN3A,HS3ST2,DPH1,DTNA,TOM1,AASDH,EDN1,EDN3,EDNRB,PHC2,HIPK3,FAM13A,TMEM132E,RASA4,ASB3,MRNIP,TUBD1,VPS13B,MFSD10,RCAN2,CDKL3,SIRPB1,TUBB3,FCGR1A,FCGR3A,FKTN,SLC9B2,FER,BAIAP2,AGAP2,WDR83,FAM49B,CAMKK2,PRELID3A,RAPGEF6,SEPT9,GATM,SULT1C4,ARFIP1,GPR162,LYVE1,MSL3,LILRB4,GPD1,GPD2,MCHR1,ZNF496,CIT,GSN,KAT7,PSIP1,UBE2QL1,MAN1B1,HLF,NEGR1,LRRC75A,MYLK2,RBPJ,KNDC1,LRRCC1,KIAA1755,TJAP1,DISP2,STMN1,NCOA7,LSS,MAN2A2,MGAT3,GIT1,COMMD5,MX1,NEFM,NELL2,VWA2,SLC11A2,ZNF827,PCDH9,ENPP2,TMEM38A,PRIMPOL,ANKRD16,PMP22,STRN3,LRP12,EPB41L4B,FSD1,PPM1B,PPP2R5E,PRKACB,MAPK4,MAPK10,GDPD1,APTX,TMEM104,QRICH1,CNTLN,MTMR10,TMEM255A,USP47,CCDC40,RBBP6,DPF2,RET,MRPS18A,RIC8B,TMLHE,KLHDC8A,CARF,CYB561D1,CCDC25,NEK11,KIAA0895L,ABCA11P,KCNIP3,FAM192A,SAFB,SALL1,ATXN2,PRCD,HES6,TNFRSF19,ZNF821,PPM1E,AMBRA1,DHX30,SLC8A1,ABTB1,SMARCA4,CDK5RAP2,MYH15,MBD5,BDP1,SOX15,KDM3A,ZSWIM8,NMNAT2,MYCBP2,KDM4C,PEG10,NKAIN2,NXT2,DIP2A,PHLDB1,VPS13A,ANKRD28,TACR1,MCF2L,TBL1X,SATB2,ZEB1,TPCN2,SYNE1,DOCK9,PCDHAC2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,DNAH7,SIRT1,GALNT17,ERCC6L2,RIMBP2,TNS1,RASD2,NPL,SYNPO2,TRIO,STXBP4,TRPM2,KCNE5,UBE2H,OSBP2,BCL2L13,VLDLR,GUSBP1,ZNF19,AMZ1,DPYSL5,FTSJ1,ZFAND5,SMARCAD1,SLC38A1,RNF103,SEMA3B,WNK3,MARCH8,FAM219B,NLRP3" MicroRNA hsa-miR-1253:mirSVR_highEffct hsa-miR-1253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-99 8.78E-96 2.54E-98 2.34E-97 272 1649 "KCNH8,ADD2,PTCHD1,SLC24A4,RTL9,TAOK1,C1QTNF3,SMIM17,SPOP,FAM135A,AMPD2,LRFN1,DPP10,ANK2,SEMA7A,LCORL,SUGT1P4-STRA6LP-CCDC180,FAM131A,MADD,CADPS,DNAH17,ATP1B3,STX16,DPY19L3,ATP6V1G2,DOCK11,LINC00847,NRP2,DST,SYNJ1,BTK,CA4,CA8,KALRN,HAP1,ISPD,LDB2,MTMR7,CD86,DGKI,ZBED1,TIGD7,SRSF11,CHN1,TAOK2,RAB33A,TPP1,QKI,SLC4A8,ABI3BP,MYRIP,SLC35F1,CPS1,HAPLN1,RNF14,ANKRD44,ZSCAN23,USP6NL,CCDC144A,CYBB,ARHGAP24,DCAF8,ZFYVE16,DGKB,DAPK1,ELMSAN1,MFAP3L,LYPD1,GRIN3A,RAB39B,DTNB,ECM2,ABCC5,AASDH,EBF1,RASGRP1,FSD1L,YAF2,SUGP2,KMT5B,ING4,EPHB1,CEP85L,CDKL3,RRAGB,FAM198B,RPS6KC1,TAOK3,DLC1,CEP78,ZSCAN30,POLR1B,FGF14,POLK,UBE2E3,FLNC,JKAMP,UFM1,DLL3,STAU2,FYB1,MEGF10,GABBR1,HRASLS5,ERAP1,NEU3,GFRA2,TCERG1,MSL3,ZNF638,KDM2B,TDRKH,STON1,PCLO,ATP2B1-AS1,GRIN2C,ATE1,ZHX1,MAN1B1,ATXN2L,HNF4G,HSF2,SMAP1,NKD1,KIAA1755,IL6ST,ITGAM,KCND1,KHK,KIF5A,STXBP5,HECTD2,PACRG,MAN2A2,MAP4,MAP6,MARK1,MBD1,TM6SF1,MEIS1,KITLG,COL28A1,MT1M,N6AMT1,LYRM9,NBL1,NCF2,CCDC13,NF1,IGSF11,PCDH9,PCSK1,PDE1C,PDE4B,GPR173,ABCB1,XRN1,PMP22,SCHIP1,ING3,POLG,POLR2F,DRAM2,PRKACB,CEP41,HYDIN,DIRAS2,SAMD9,GDPD2,CNTLN,TMEM260,ZSCAN2,NKAIN1,NWD1,MSANTD2,RDX,MORC4,UBR7,RGS4,PBRM1,DCUN1D2,TMLHE,CARF,CYB561D1,ROBO2,RPL15,FBXW7,ATP8B4,TCP11L1,LRRK2,HSD11B1L,ATAT1,RTN1,CSRNP3,ATXN7,SCN8A,PRCD,TNFRSF19,ZFP30,PPM1E,SHMT2,R3HDM2,NLGN1,SLA,WDR47,CCDC88A,SLC9A5,SLC12A2,ATF7IP,TET1,INTS9,ANKRD36,FAM126B,DOP1A,KDM4C,UNC5B,SPTAN1,ATP10B,PBLD,CLASP2,ERBIN,TTBK2,DIP2A,VPS13A,COBL,FAM208A,ADGRL3,TCF4,TPCN2,SYNE1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEK,AP4E1,MTMR14,TK2,BHLHB9,LRRC8A,TPM2,ZNF346,METTL3,STXBP4,DCBLD1,TSC1,HSPBP1,LAT2,ZBTB14,KCNT2,ELFN1,NDRG4,TCEAL7,ZNF142,REEP1,FSTL5,MAP3K12,STOX2,TMEM178A,HPS4,VPS35L,FAM47E,FAM13C,KAT6A,NLRP3,NHSL1,AP3B2" MicroRNA hsa-miR-3201:mirSVR_lowEffct hsa-miR-3201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.38E-99 1.33E-95 3.84E-98 3.53E-97 233 1209 "RALGAPA1,KCNH8,CLK4,NCKAP5,NDRG3,GALNT13,INTS2,CC2D2A,ZNF578,SMIM17,SPOP,ALCAM,SRPX,EP400,ZNF582,ADAM15,ADGRB3,CFLAR,DST,C5,CA8,KALRN,PTBP2,RUNX1T1,CLDN10,KRIT1,CCNH,P2RX6,CDC25B,DCLK1,CLGN,NOG,CFL2,COPB2,SRSF11,B4GALT6,ABCG2,MAP4K4,CNN3,AKAP7,IQCK,AKAP6,ABI3BP,ENTPD4,ANKRD44,SNCAIP,PDE4DIP,DZIP3,CYBB,BOC,RIPOR2,HDAC4,LONRF1,DGKG,ELMSAN1,TIAM2,FBXL5,KIAA0319,RHOBTB1,PLPPR4,TMCC2,DMD,DMTF1,DPP6,ABCC5,DNM1L,EBF1,WDPCP,EDN3,ANKRD46,HEYL,SEMA3D,YAF2,MBNL2,AASS,KCTD3,EIF4G2,CALCRL,PAN3,EIF1,EPB41,STX2,ZNF549,ETV1,DNAJC27,GMPR2,TUBA1B,TAOK3,SPSB4,FGF12,MEX3B,FOXO3,NBEA,TRIM16,DLL3,MPP6,GABRB3,GABRG1,ZNF234,DISC1,LRRC37A6P,GATM,NEU3,AHDC1,MMADHC,TOX3,TNRC6A,GPD2,STON1,PCLO,GRIA2,FAM19A2,RNF165,FAM107A,GUCY1B1,RASSF8,PADI2,HLF,ZNF491,ZDHHC15,SMAP1,FAM69A,CAMK2N2,STMN1,LIG4,PAXBP1,HECTD2,PACRG,MATN3,MBP,CHIC1,LRP1B,SHC3,MEF2C,MEIS2,MYO9A,ZNF862,NDP,NEK1,CNOT4,DNHD1,SLC11A2,PCSK5,PDPK1,STRN3,LRP12,PPP2R2C,PKIA,HYDIN,PTPRD,ACSM5,CEP97,SH3TC2,RASGRF1,ZDHHC14,REV3L,RNH1,CCDC82,C12orf49,ADAL,RPS6KA2,LRRK2,AP1AR,SALL1,SCP2,SEC14L1,MRAS,CPEB3,FBXO11,FHOD3,NLGN1,FAM81A,KANSL3,CCDC88A,BTBD7,CXXC4,RCOR3,KIF13A,SNRPN,BDP1,HECW1,MYCBP2,KDM4C,IQSEC2,NFASC,ITPRID2,RHBDL3,VPS13A,PJA1,EXOC7,KIAA1107,TBL1X,DMXL2,CUX2,TRIM2,RPGRIP1L,CLASP1,NSD1,TEK,AP4E1,SLC44A1,TIAM1,TLR4,ERCC6L2,FAM124A,CSMD1,CABIN1,PIK3R5,NPL,SYNPO2,TRIO,PDSS1,TTC3,PRR18,VLDLR,WIPF1,XPO1,XRCC4,LYPD6,ZBTB38,EML6,ANKS1B,SMARCAD1,CADM2,SLC38A1,ADAMTS9,NAV3,FIP1L1,TRIM16L,TIGD6,RNF170,FRMD6,NETO1" MicroRNA hsa-miR-3156:mirSVR_lowEffct hsa-miR-3156:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.76E-99 1.55E-95 4.44E-98 4.09E-97 270 1629 "FMNL2,KLHL32,TMCC3,ADORA2A,ESYT2,DPY19L2P4,SLC24A4,INTS2,KCTD16,WDR35,AK2,ZNF578,HFM1,AMPD2,ZFAT,OGT,ANK2,MAP4K3,PKP4,PHYHD1,PPFIA3,AQP6,TMEFF1,CDK13,CCDC74A,NUMB,ATP6V1G2,MPDZ,BID,PROM1,KSR1,SGCE,RAB29,CACNB4,PTBP2,CBR1,CD86,C1orf52,ZBED1,CDR1,CCPG1,DIS3L,ASIC3,MS4A7,B4GALT6,SRP14-AS1,IGLON5,ARHGEF6,IQCK,ARMC8,AKAP6,RCHY1,GDA,CS,RGS6,CSNK1G3,PDE4DIP,DZIP3,PPP1R16B,GREB1,PUM1,DCAF4,KIAA0408,ARHGAP24,DCAF8,MAML1,DAPK1,IP6K1,FBXL5,KLHL3,SPOCK3,WDR20,FAM107B,CPEB2,SLC12A6,E2F5,AASDH,SNX29,EDN1,ANKRD46,HEYL,KLHL5,TMTC1,SUGP2,C3orf18,CALCRL,USPL1,VPS13B,GPHN,RABEPK,DNAJC27,KATNAL1,ADGRV1,RPS6KC1,ACSL4,TAOK3,MED12L,POLR1B,FGF11,UBE2E3,IP6K2,EVL,ANKFY1,SLC37A3,TMEM107,SMC2,UFM1,TPK1,ST6GALNAC3,STAU2,GABRB3,GAD1,ERAP1,ZNF559,SEPT9,NEU3,GCNT2,GHR,TCERG1,MSL3,ZNF638,KDM2B,GRB10,GRIA2,ZNF496,LINC01089,GSTM5,NXPH3,ARHGAP36,MIER3,SYNPO,HNMT,MYLK2,IGF1,SCIN,IL6ST,INPP5B,CREG2,MARK1,MAT2A,MEF2C,AFF1,XRRA1,MMP16,SAMD5,MSR1,PTOV1,N6AMT1,RTL5,NF1,NOVA1,OCRL,OXTR,PCDH9,PCSK1,PDE1B,ZNF655,SNX10,SLC25A23,PURG,PPM1B,TATDN3,PPP2R2C,DIRAS2,DCHS2,ELOVL2,PTPRE,PTPRH,PTPRO,C1orf109,FAM66C,SH3TC2,SUSD4,RBBP6,RADX,ZDHHC14,UBR7,RGS12,PRIMA1,KIF7,RIC8B,ELP2,CCDC102B,ZC3H14,MEG3,ATAT1,CLIP1,SALL1,ATXN2,SCP2,SEC14L1,KIF21A,MYO18A,FNDC3A,SLA,SLC2A5,PPP4R3A,EPN2,SLC6A11,SEPHS1,SLC8A1,TRIM67,NAPB,ELMO2,IFT122,ANKRD36,MBD5,SNRPN,TRERF1,SOX11,ZSWIM8,SP4,GLT8D1,ERC1,RBM26,DDN,NFASC,LHPP,POGZ,ITPRID2,STAU1,CEP68,TTBK2,NSFL1C,KLHL7,JMJD6,VPS13A,NUDT10,SYP,DNMBP,TBCEL,SATB2,ZEB1,PCDHB4,PUM2,TNS2,FRYL,DICER1-AS1,ZFPM2,C18orf54,ZNF106,ACTR6,TP53BP1,RGMB,TRIO,RUNDC3B,TRPS1,DCBLD1,RUSC1,LINC00689,FLRT2,XRCC4,ZNF708,ZNF28,TRIM9,ZNF74,FSTL5,EMSY,DNALI1,EVI5,PARP11,DNAH10,PHTF2,RSPRY1,RNF170,SNX14,FRMD6,IFT88,SOCS4,GAN" MicroRNA hsa-miR-1178:mirSVR_lowEffct hsa-miR-1178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.15E-99 1.76E-95 5.05E-98 4.65E-97 269 1618 "RALGAPA1,FMNL2,KLHL32,AXIN2,FZD9,KIAA1211,SLC24A4,AP2A1,ZNF608,KLHL13,AGT,CC2D2A,HFM1,C1QTNF3,CEP126,AMPD3,ANK2,EP400,SHROOM2,TMEFF1,RGS20,ARRB2,SLC2A11,BACH1,MIR9-3HG,DST,ARHGEF7,CALB1,THSD7A,CALM1,KALRN,RHBDL1,CBR1,SCARB1,ENTPD6,CDC25B,LRRFIP1,L3MBTL4,CLGN,NOG,UBE2L6,CHN2,CHRNA4,LHX2,FBXO7,C4orf33,COL4A5,MYRIP,CNRIP1,CLOCK,CDC42BPB,PREPL,RBM39,CRY2,GDA,TRIM69,RGS6,SEC24C,PDE4DIP,FAM169A,DZIP3,GREB1,ARHGEF4,CCDC144A,BOC,HDAC9,GAPVD1,RIPOR2,KIAA0586,DAPK1,JAKMIP2,MYEF2,C2CD2L,KIAA0319,DDX46,SV2B,TMCC2,GRIN3A,SLC29A4,NR1D2,DRP2,DTNA,SEZ6L2,KLHL5,FRY,CELSR3,EGFR,KMT5B,KCTD3,EIF5,RCAN2,STX2,DNAJC27,ANKMY1,SIRPB1,EYA1,EZH1,FAM198B,FCGR1B,KAT8,SPSB4,FGF12,FHL1,POLK,SUCO,IQCG,FOXO3,PSD2,STAU2,GABRG1,GAD1,B4GALNT1,MTHFD2,ZNF559,INPP5K,LRRC37A6P,KIAA1841,NEU3,GGT7,ZNF276,RAB30,KIAA1958,GNAL,ZNF782,ADGRA3,TMEM121B,PCLO,FAM19A2,RNFT2,ADAMTS6,NCKAP1L,ATXN2L,MIER3,HNMT,SHISA6,SOWAHA,GAREM2,RBPJ,ITPKB,IPO5,SYTL4,LRP1B,MEF2C,SCAMP5,PPM1L,MN1,GIT1,N6AMT1,MYO7A,RTL5,ZNF862,NEFH,DNHD1,IGSF11,LOC100128398,PCSK5,CCSER2,SMIM7,ZNF426,MTRF1L,PRIMPOL,ING3,EPB41L4B,PPM1B,TATDN3,LRRN3,KANSL1,PPP5C,PRKACB,PRKCB,MAPK3,MAPK9,SAMD9,BDNF-AS,ELOVL2,PTPRN,PTPRO,C1orf109,TUG1,STRC,TMEM255A,RASGRF1,NUDT11,ROBO2,ARMH4,ZC3H14,GLDN,TCP11L1,MAP6D1,ABCA11P,ZNF568,GALNT10,MRAS,TRA2B,SCAF8,FBXO11,ST6GAL1,CCDC92,NUBPL,ABLIM3,FAM81A,DHX30,SLC6A11,ELMO2,LGI3,SMARCD3,ANKRD36,MBD5,FAIM2,SNRPN,DOP1A,ZSWIM8,IZUMO4,TSPYL2,DDN,SPART,PBLD,TROVE2,POGZ,ITPRID2,ZNF302,LARP4,CEP68,STXBP1,ASTN2,C12orf76,TACR1,ANKRD12,CAMTA1,FAM208A,ADGRL3,KIAA1107,FBXW11,ZFP90,ZEB1,SLC19A3,TNS2,RNF216P1,FAM200B,DNAH7,ITGB3BP,TIAM1,HEY1,TPM1,CDK20,NPL,ZNF346,AMACR,FLRT2,PLEKHH2,USP1,WIPF1,XRCC4,PCDH20,TRIM9,ZNF70,AMZ1,ANKS1B,UPF3A,EMSY,EVI5,STOX2,CIAPIN1,SEMA3B,NAV3,URM1,FAM47E,CASC15,JPH3" MicroRNA hsa-miR-3189:mirSVR_lowEffct hsa-miR-3189:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.29E-99 1.84E-95 5.25E-98 4.83E-97 265 1571 "SYN3,EMILIN3,KLHL32,ADD2,PWWP2A,KIAA1211,RNF150,OLMALINC,MTUS1,NME5,CC2D2A,ABCD2,CARNS1,LRCH2,C6orf89,FAM131A,PPFIA3,LGR5,SHROOM2,CDK10,SPTBN4,ARHGDIG,NUMB,TMEM108,EIF4G3,ATP6V0A1,ADAM23,TTLL9,ADGRB2,BCL7A,CFLAR,ARHGEF7,CASTOR3,CACNA1G,C5,CA4,CACNA1B,CABP7,VXN,CBLN1,CBR1,CBS,USP2,P2RX6,LARGE1,COPB2,RCBTB2,CHN2,EPS15L1,TPP1,FAM189A2,MAP4K4,CNGA3,WHRN,SUMF2,LETMD1,SLC4A8,SMARCAL1,IGDCC3,ZNF385A,CPS1,FAM171B,SEC31B,CREM,ANKRD44,CSF2RA,ARHGEF10,UBXN2A,PHF14,RUBCN,FAM131B,SEC14L5,CCDC144A,RIPOR2,DGKG,IP6K1,DNM1,HS3ST2,SLC29A4,SHANK1,DOCK2,CASP8AP2,ACOT8,DTNA,GOLT1B,E2F5,AASDH,ANKRD46,FCF1,TMTC1,APH1A,MBNL2,TMEM132E,RASA4,IRAK4,TENM1,EMX2,ERCC2,SPEG,MRPL37,EXTL2,ADGRV1,GMPR2,REEP2,TAOK3,DLC1,FCGRT,PPP1R1B,FER,GTF2IRD2,FGF1,FGF14,MAD2L2,SCARA3,VTI1B,ZBED3,PDLIM5,ATP2C1,HRASLS5,GABRB3,RAPGEF6,MTHFD2,LRRC37A6P,GGT5,TXNL4A,GLI2,GLYR1,TNRC6A,STON1,MCHR1,SPACA9,RNFT2,SLC2A6,ATOH8,HAS2,PADI2,BACH2,SHISA6,RBPJ,SCIN,ITGA7,METTL21A,CAMK2N2,MAN2A2,MAP4,MAP6,MARK3,MATK,MATN3,MBD1,ADAM11,MEIS1,KCTD6,MID1,MMP16,NFE2L2,NME4,SLC11A2,NTRK2,NTRK3,OGG1,OPA1,ZNF827,PCDH9,GPR173,PFKFB4,OLA1,PIK3R1,ZNF655,CCSER2,PKD1,JAKMIP1,ANKRD16,STRN3,LRP12,NECAB2,EPB41L4B,PPARA,NKAIN4,MASP1,PSD,WBP1L,PIGG,CNTLN,BDNF-AS,CASTOR1,PTPRH,PID1,FAM66C,ZNF793,KHDRBS2,ZDHHC14,RGS3,TMLHE,SNX22,RPL15,ADAL,RPS6KA2,ST6GALNAC6,NCBP3,DGLUCY,MAPK12,SEMA6D,FNIP1,SMPD3,PEAR1,COPZ1,FAM102A,SH3GL3,PPM1E,ARX,AMBRA1,ANKRD6,ABLIM3,PREX2,KANSL3,SLC6A11,IFT122,INAVA,ZNF415,RBM34,SOX11,KDM4C,DDN,ITPRID2,MESP1,ZC4H2,NKAIN2,SULF2,SEPT3,SYP,SYT1,TBCEL,TBL1X,SMG6,TCF12,RNF175,RNF216P1,VWCE,FAM200B,ENHO,MTMR14,ACTR6,RIMBP2,CDK20,TPM2,ZNF346,SYNPO2,TRIO,NUTM2A,BCL2L13,CCDC14,ATP6V0E2,NDRG4,CRB2,ZBTB38,ZNF154,PCBP1-AS1,MEIS3,SEMA3B,NAV3,ST7,MARCH8,UBE3B,TIGD6" MicroRNA hsa-miR-27a:mirSVR_highEffct hsa-miR-27a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.29E-99 1.84E-95 5.25E-98 4.83E-97 259 1501 "RALGAPA1,NCKAP5,CCDC85A,ADORA1,KIAA1211,PTCHD1,OLMALINC,ZNF608,INTS2,HACE1,WDR35,TAOK1,SEMA6A,ALCAM,DPP10,ANK2,SEMA7A,PKP4,APBA2,DDO,VAT1L,NCOA1,STX16,ZNF582,RNF182,RIPK1,NRP2,PROM1,CACNA1A,MTMR7,SCARB1,C1orf52,ZMYM4,MAGI1,CFL2,MS4A7,CLCN3,QKI,CNN3,ARHGEF6,AKAP7,ARMC8,LETMD1,ZFP28,ZNF385A,SLC35F1,CRMP1,HAPLN1,GDA,SEC24C,LRRC3B,SUSD5,VCAN,HDAC9,GAPVD1,RIPOR2,DCAF8,LONRF1,KCTD8,DGKB,TMEM170A,PABPC5,POM121,SNAP91,CHRDL1,GRIN3A,NR1D2,RCAN1,ARRDC4,DTNA,DNM1L,E2F5,EBF1,EDNRA,TMTC1,FAM13A,EGFR,MBNL2,ASB3,EIF5,RGS17,CALCRL,EPB41,RCAN2,EYA1,EZH1,HSPA12B,FGF1,FGF12,FGF13,FGF14,SUCO,RGPD5,ST6GALNAC3,NSG1,AP4B1,BRSK1,OGA,NEURL4,GABRB3,IQGAP2,ERAP1,DISC1,NEU3,ARFIP1,PCDH17,PPARGC1A,GLI2,TOX3,ZNF638,ADGRA3,GPD2,GPR37,RNF165,RNFT2,FAM222A,ZHX1,MIER3,CFAP126,HSPA1L,MSL1,SOWAHA,ZIC5,ZNF678,INPP1,NME9,KCNJ16,CREG2,STXBP5,PAXBP1,HECTD2,NCOA7,SMAD1,SMAD9,MARK1,LYPLAL1,MAT2A,AQP11,MATN3,MBD1,MEIS2,KITLG,ZNF680,MXI1,P2RY13,NEK1,NF1,NFE2L2,NOVA1,PCDH9,PDE3A,PRIMPOL,LRP12,SEPT4,PPM1B,PPP3CA,CEP41,PKIA,PRKCB,MAPK9,GRAMD1C,HYDIN,DCHS2,RELN,PIGG,CNTLN,MTMR10,ZSCAN32,QDPR,SH3TC2,FAT4,FAM184A,ENOX1,ZNF493,RET,REV3L,ERI2,RFX3,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,TMLHE,RORB,ELP2,FBXW7,ATP8B4,MEG3,NCBP3,TRAPPC13,ARX,CPEB3,SHC4,HKDC1,CHD9,SLA,EPN2,SLC8A1,KBTBD4,ZNF334,TET1,CPEB4,RCOR3,SNAP25,TMCC1,BDP1,KDM3A,KDM4C,PEG10,TROVE2,SSTR1,LARP4,ERBIN,NXT2,SEPT8,TTBK2,NECAB1,ARHGEF9,VPS13A,MMS19,TACC1,CAMTA1,TAF9,PDLIM2,TCEA1,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,FRYL,SIK3,FAM200B,THRA,ACTR6,CSMD1,TPM1,NPL,SYNPO2,TSC1,TTC3,CLHC1,GORASP1,PLEKHH2,ZNF709,XPO1,ZNF708,ZNF540,MKRN3,FSTL5,ZSCAN26,SMARCAD1,DHX33,TMEM178A,DOCK8,JMJD1C,ADAMTS10,NETO1" MicroRNA hsa-miR-146a:mirSVR_lowEffct hsa-miR-146a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-99 2.69E-95 7.65E-98 7.05E-97 292 1902 "ACADM,EMILIN3,XKR4,FMNL2,CCDC85A,ADD1,RNF150,MTA3,AP2A2,ZNF608,CASKIN1,OSBPL1A,WDR35,OSBPL8,ZNF578,ABCD2,GPRASP2,SYT13,AMPD3,CDC42BPA,ANK2,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,USP37,PPP4R4,DNAH17,PCDHGB4,ADAM23,ADAM15,LINC00847,BCHE,RGS9,BLM,DST,SYNJ1,CACNB4,CALB1,SLC25A14,PRC1,CD86,DCLK1,DLGAP1,UBE2L6,CNTN1,FAM149A,AKAP5,RCHY1,ZFP28,SEC31B,CREM,RBM39,RNF14,ANKRD44,CRYM,CS,OSBPL3,GALNT9,PNPLA8,GREB1,ARHGEF4,ZSCAN23,ARHGAP32,GAPVD1,SNPH,RASSF2,IST1,GIT2,DNAL1,HEPH,FBXL5,KIAA0319,LYPD1,SGSM2,DLX1,GRIN3A,DOCK2,HEYL,EBI3,MBNL2,EGR3,TMEM132E,AASS,TENM1,CALCRL,RABEPK,NCALD,MRPL10,TLR7,KATNAL1,ADGRV1,MRVI1,FAM198B,DLC1,ST3GAL6,CHST15,ZSCAN30,FECH,FER,GTF2IRD2,OLFM1,PCYOX1,SYNCRIP,IQCG,FLT1,SMC2,ATP6V1H,ATP2C1,ZNF605,STAU2,TVP23A,GABRG1,GAD1,IP6K3,ACSS1,KIAA1841,SULT1C4,SESN1,TOX3,MSL3,DCLK2,FERMT2,LILRB4,SPACA9,GRM2,PRDM5,ADAMTS6,MUM1,PADI2,ZHX1,VSIG4,AGBL5,CELF5,MSL1,GAREM2,SCIN,IL6R,ZNF678,CREG2,LAMA2,SYTL4,NCOA7,ZFYVE27,MAP4,MAP6,LYPLAL1,MAT2A,MBD1,CHIC1,TM6SF1,MEIS1,PPM1L,AFDN,MXI1,LAYN,MYO5A,MYO7A,ZNF862,SFR1,NF1,NPR2,NTRK2,NTRK3,OPA1,PCDHGC3,PCDH9,PDPK1,PFKFB3,NLGN3,XRN1,KCTD15,NLE1,PLCL1,TRHDE,MAGEL2,PPM1B,PPP2R5E,PRKACB,GRAMD1C,PIGG,CNTLN,ZSCAN32,TMEM255A,SH3TC2,NWD1,RASGRF2,RFX2,RNASEL,C12orf49,ELP2,NEK11,ZC3H14,KIAA0895L,GLDN,ATAT1,SALL1,SATB1,LRFN5,PRCD,SCP2,GALNT10,FOXRED1,MRAS,TRA2B,COPZ1,CHD9,FHOD3,PPP4R3A,DHX30,ARHGEF40,SLC9A5,SLC11A1,ZFP1,RCOR3,INAVA,LIMCH1,MBD5,SNRPN,DOP1A,TRERF1,FNBP1,DOK5,ZSWIM8,SPART,ATP10B,ITPRID2,NECAB1,ZC3H4,SYN2,TACR1,DNMBP,PDLIM2,MGRN1,ATMIN,SIN3B,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,USP32P1,FRYL,CCDC173,SIK3,VWCE,PMS2CL,DICER1,SIRT1,ZFPM2,ITGB3BP,GALNT17,TIAM1,MTMR14,TIMP4,BHLHB9,TLR4,RIMBP2,PRRT1,CSMD1,ZNF346,SYNPO2,KCNE5,TTTY15,CLHC1,WIPF1,WRN,XPO1,LYPD6,ZFAND5,SMARCAD1,EMSY,DNALI1,SLC38A1,LINC02210,ADAMTS9,HPS4,FAM47E,PCBP4,MPPE1,FZD3,UBE3B,FRMD6,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-153:mirSVR_lowEffct hsa-miR-153:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.60E-99 3.13E-95 8.87E-98 8.17E-97 268 1610 "EMILIN3,XKR4,NDRG3,FMNL2,ADCY6,ADD1,AXIN2,USP31,PWWP2A,PTCHD1,BEND6,WDR35,ZNF578,SMIM17,CARNS1,UNC79,BEGAIN,AMPH,CCDC146,APBB2,UPRT,DDO,CASK,TMEFF1,SPTBN4,ARNTL,ATP2A2,DPY19L3,DOCK11,ADGRB3,CACNA1G,CACNA1B,DDR1,CACNB4,CALB1,CAMK2G,CH25H,RUNX1T1,ARHGEF25,CBR1,CLDN10,LDB2,SCARB1,DGKI,AP4M1,CCPG1,SRSF11,MS4A7,CNOT8,CLCN3,CLTC,CNGA3,AKAP7,IQCK,ARMC8,AHCTF1,ZNF521,ZFP28,C2CD2,RBM39,ANKRD44,RGS6,SOCS5,SLITRK5,APPL1,USP6NL,SNPH,PABPC5,BRINP1,ELMSAN1,PLPPR4,SACS,DLX1,EXOG,USP3,CDON,CPEB2,DNAJB6,EDN1,ANKRD46,KLHL5,TMTC1,FSD1L,PHF20L1,PLEKHA1,RGS17,PAN3,VPS13B,GPHN,NCALD,KATNAL1,CLVS1,RACK1,CHST15,FER,FGF12,POLK,ATP13A4,SLC37A3,PDLIM5,TPK1,ATP2C1,ZNF605,KHDRBS3,STAU2,DOT1L,MEGF11,TRAF3IP2,GAD1,SULT1C4,PPARGC1A,KDM2B,HTATSF1,RAB40B,FERMT2,PRUNE2,LPAR4,GRIA2,PLCD4,RNF165,AP4S1,PSIP1,HAS2,DDX19B,MIER3,IGFBPL1,SMAP1,IRF8,ZNF181,RBPJ,KIAA1755,INSM1,KCNB1,KCND2,KCNH2,STXBP5,LIG4,PAXBP1,LMO2,HECTD2,PACRG,AQP11,SHC3,MEIS1,SCAMP5,MITF,MKLN1,NEFM,NEFH,NF1,CNOT4,NPR2,SLC11A2,NTRK3,CLDN11,GLIPR1L2,PCDH8,PDE4D,GPR85,GNG2,PIK3R1,FAM216A,PURG,PDZRN4,MAPKAP1,SCHIP1,ING3,SEPT4,DRAM2,PPM1B,PPP2R5E,PRKAB2,PRKACB,PKIA,MAPK4,GRAMD1C,DCHS2,MASP1,VPS13C,ANKHD1,MTMR10,PTPRB,TUG1,RAD51D,FAT4,REV3L,KIF7,SLC25A36,ZFHX4,LGI2,CCDC82,TMLHE,ROBO1,SNX22,ARMH4,BAALC,GLDN,ATAT1,STX1B,SCP2,SCAF8,CHD9,FBXO11,KANSL3,SLC8A1,ELMO2,CPEB4,EPC1,LIMCH1,SNCA,LMBRD1,MYO16,USP33,BDP1,SP4,HECW1,ZNF423,TSPYL2,ITPRID2,ZSCAN29,SEPT8,TTBK2,KANK1,NSFL1C,NECAB1,SYNE2,SYN2,SYPL1,SYT1,AGTPBP1,TCF4,ZFP90,CUX2,RPGRIP1L,DOCK9,PCDHB10,USP32P1,HIF3A,TEK,DICER1,SIRT1,HEY1,ASXL3,FAM124A,RGMB,SMUG1,TRIO,DCBLD1,TSN,RPL7L1,PLEKHH2,VLDLR,ZNF711,ZFAND5,SLC30A3,STOX2,PRDM10,TUBA1A,NAV3,EPM2A,RTN4,UBE3B,FBXO36,ADAMTSL3,NHSL1,FXR1,IFT88,SPATA13" MicroRNA hsa-miR-324-3p:mirSVR_lowEffct hsa-miR-324-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.65E-99 3.72E-95 1.05E-97 9.68E-97 293 1917 "ABCF1,ABR,ASIC1,NDRG2,ADCY6,ADD2,FZD9,ADORA1,ADORA2A,KIAA1211,ADRA1B,PCDH19,OSBPL1A,C1QTNF1,ADGRF5,CARNS1,FAM135A,FGD2,MYH7B,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,UPRT,PPFIA3,MADD,SPTBN4,ARNTL,CDK13,CHID1,ZNF583,SLC2A11,RNF182,TTLL9,AZGP1,CACNA1I,KALRN,ARHGEF25,LDB2,USP6,CD86,CDC25B,COPB2,CBARP,CHGB,ASIC3,PLEKHB1,MYL6B,FBXO7,IGLON5,ARHGEF6,SUMF2,SMARCAL1,SEC31B,SH2B1,GDA,SNCAIP,CSF2RA,SLITRK5,GPSM1,RUBCN,KATNAL2,EARS2,DGKG,ARMCX4,TIAM2,MFAP3L,C2CD2L,LYPD1,POM121,SGSM2,CHRDL1,DMD,DPYSL2,TOM1,DNM1L,AASDH,EDN1,EDNRB,PHC2,CNNM1,RASGRP1,CELSR3,FAM13A,TMEM132E,ING4,TNK2,C3orf18,CALCRL,RASGRP2,SRRM1,SPEG,MRPL37,RASL12,MRVI1,CLVS1,TMEM132C,PTK2B,PRAM1,TUBB3,DLC1,FCGR1A,FGF11,SPSB4,BAIAP2,FOXF2,POMT1,KHDRBS3,CELF1,DLL3,HHIPL1,TPPP3,AP4B1,DOT1L,FYB1,B4GALNT1,ZNF234,GHDC,TMEM8B,DISC1,SEPT9,INPP5K,CPLX2,ALDH1L1,TUBA8,GFER,USP19,RUNDC3A,BRD8,ZNF782,GPD1,CCDC184,TMEM121B,DIDO1,C1QL4,ADAMTS13,GRIN2C,GSN,CLASRP,KAT7,PADI2,MAN1B1,NCKAP1L,AGBL5,ZNF491,DHX35,SHISA6,ICA1,IRF8,MSL1,MYLK2,KNDC1,IL6R,TMEM240,INPP5B,ITGA7,CDH20,KCND1,KCNH2,STXBP5,L1CAM,STMN1,SFXN5,MAP6,MEIS1,MEIS2,MGAT3,SCAMP5,AFDN,XRRA1,GIT1,NELL2,NF1,CNOT4,DNHD1,NTRK3,PDE4A,PDE4B,OLA1,DUSP26,SNX10,PLCB2,PRIMPOL,STRN3,ING3,RETREG2,POU6F1,TATDN3,KANSL1,HYDIN,WBP1L,TMEM104,PTN,PTPRB,CASTOR1,PTPRG,NKAIN1,USP47,IQSEC3,GAL3ST4,TRIM68,ZDHHC4,RGS3,KIF7,LGI2,EXD2,KLHDC8A,ARMC5,KIRREL1,SNX22,EPHA10,KIAA0895L,ZNF671,ATP8B4,SGSM1,STK32B,PTGR2,MEG3,ABCA11P,HSD11B1L,ATAT1,SATB1,SBF1,SCP2,HES6,SEC14L1,GALNT10,PPM1E,SHC4,CHD9,NLGN1,PEX26,EPN2,SLC6A8,SLC6A11,SLC11A1,SLC12A4,SMARCC2,CDK5RAP2,MAPKBP1,SNRPN,USP33,FAM219A,PDZD2,TRERF1,BDP1,TSNAXIP1,ZSWIM8,NMNAT2,KDM4C,ERC1,SPTB,ATP10B,SEPT8,NUDT10,TMEM150C,CAMTA1,EXOC7,NEU4,CUX2,SZT2,SYNE1,TNS2,FRYL,HIF3A,CYB561A3,RNF216P1,PMS2CL,ZNF34,BEX4,TPM1,NPL,ZNF346,PPIL6,UBTF,PLEKHH2,LMF1,KLC2,RICTOR,LGI4,ELFN1,MKRN3,PCBP1-AS1,MAP3K12,SLC38A1,SEMA3B,SIGLEC10,SLC17A7,PPP1R3F,PCBP4,SMIM8,ADAMTSL3,RNF170,FAM181A" MicroRNA hsa-miR-4272:mirSVR_highEffct hsa-miR-4272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.70E-99 3.75E-95 1.06E-97 9.72E-97 243 1324 "SYS1,KDM5D,CCDC85A,GALNT13,BRAP,AP2A2,WDR35,CC2D2A,SMIM17,LRCH2,APC,PPP4R4,ARNTL,CDK13,MARK4,ZSCAN18,RASL11B,ATP2A2,RNF182,ATP6V0A1,BACH1,JAZF1,CACNA1G,WASF1,CACNA1A,THSD7A,ZNF501,LDB2,KRIT1,USP6,CBFA2T2,DGKI,CCPG1,CFL2,SOCS6,LHX2,PLAA,CLCN3,QKI,AKAP7,ARMC8,FAM149A,AKAP5,RCHY1,GDA,PHF14,PNPLA8,DOCK4,ZFYVE16,CENPL,LONRF1,ARMCX2,POM121,RHOBTB1,SPOCK3,WDR20,SEC16A,CPEB2,RCAN1,EDN3,SEMA3D,TMTC1,FAM13A,PLEKHA1,CALCRL,CDKL3,ETV1,RPS6KC1,PTK2B,CEP78,ZSCAN30,MED12L,FGF13,FGF14,BAIAP2,FHL1,POLK,SUCO,ANKFY1,SLC37A3,FOLH1,C2orf88,UFM1,PDLIM5,CELF1,STAU2,ZMAT1,CHL1,SIGLEC8,C15orf41,CPLX1,ARFIP1,MALT1,RNPS1,KDM2B,GPD2,TDRKH,ATP2B1-AS1,GRIA2,PRDM5,ZNF496,GUCY1B1,RASSF8,FRMD3,HLF,CFAP126,NEGR1,IDH3A,ZIC5,RBPJ,KCND2,KCNN2,KTN1,LAMP2,NCOA7,PACRG,EFHB,SRSF12,KITLG,MITF,AFDN,XRRA1,COL28A1,MSR1,NRBP2,NEK1,NELL2,NFE2L2,CNOT4,SLC11A2,NRCAM,TBC1D25,CLDN11,PRTG,PDE4B,SLC10A4,SNX10,PCDH18,PURG,STRN3,PSAT1,SEPT4,PPARA,PPM1B,TATDN3,PPP2R2C,PPP2R5E,PKIA,EPDR1,GRAMD1C,CNTLN,MTMR10,PTPRE,PTPRO,PPP2R3C,RAD17,FAT4,ZNF493,OXR1,RASGRF2,RBBP6,GAL3ST4,REV3L,GTDC1,SLC25A36,C12orf49,RPL15,TCP11L1,LRRK2,CLIP1,ZNF354C,LRFN5,FNDC3A,FHOD3,BTBD3,SLC14A1,ATF7IP,TET1,CPEB4,LIMCH1,KIF13A,USP33,TRERF1,SP4,SPP1,ZBTB43,LMO3,PBLD,TROVE2,TTBK2,KLHL7,SYNE2,ADAMTS17,PLCB1,MTCL1,TAF9,ADGRL3,KLHL4,KIAA0930,TPCN2,RPGRIP1L,PCDHGA11,SYNE1,DOCK9,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,AP4E1,THRA,TLR4,NR2E1,TP53BP1,C9orf85,RGMB,ANKRD20A2,UBE3A,VLDLR,ZFP37,ZBTB14,ZIC1,ZNF24,MICU3,ZNF70,SMARCAD1,EMSY,CADM2,PRTFDC1,HPS4,RGS7BP,FZD3,HNRNPA3,PHTF2,CASC15,RNF170,SOCS4" MicroRNA hsa-miR-519c-3p:mirSVR_lowEffct hsa-miR-519c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.38E-99 4.13E-95 1.16E-97 1.07E-96 282 1781 "SYS1,GALNT16,CCDC85A,ADD1,USP31,RNF150,PTCHD1,ADRA1B,BEND6,HECW2,WDR35,OSBPL8,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,TNRC6C,LGR5,CDK10,PLA2G4C,MARCH3,NCOA1,NUMB,INSYN2B,DPY19L3,TTLL9,ADGRB3,RGS11,BCL7A,FUBP1,MTMR2,SGCE,KALRN,CAMK2G,CBR1,CBFA2T2,C1orf52,NOG,MS4A7,B4GALT6,EPS15L1,CLTC,QKI,CNR1,IQCK,AKAP5,ZFP28,CNRIP1,AKAP12,HAPLN1,TRIM69,PDE4DIP,CNTNAP2,FAM169A,APPL1,DCAF4,USP6NL,GAPVD1,ZNF337,DGKB,DGKG,DNAL1,SPATA2,ZNF804A,MFAP3L,ZC3H11A,GUCD1,RHOBTB1,SNAP91,HS3ST2,SLC25A18,ACOT8,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,PAN3,EMX2,EPB41,ERBB4,MRPL37,TLR7,KATNAL1,ST3GAL6,MED12L,POLK,SEC23B,PCYOX1,ATP13A4,ANKFY1,NOP56,NELFCD,CELF1,GAD1,ZNF274,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,DBF4,TNRC6A,MSL3,CBX1,GPT2,ADGRA3,GPR34,GPR37,PCLO,ZNF496,BTN2A1,SOX21,GUCY1A1,IRAK3,SHISA6,CELF5,SMAP1,IGF1,SLC35G1,KIT,LAMP2,CAMK2N2,SFXN5,ZNF667-AS1,MAP2,MAP6,MAPT,SCAMP5,AFF1,PTOV1,NRBP2,TAGLN3,MXI1,LYRM9,MYO5A,MYO9A,NBL1,NCF2,SFR1,NFIX,NPTX2,NUCB2,OPRL1,PAX6,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,DUSP26,XRN1,GPSM2,SLC25A23,LRP12,SDK2,ING3,MINDY2,CCDC144B,MAPK3,MAPK4,DEF8,MTMR10,PTPRD,PTPRE,FAM184A,OXR1,RASGRF1,RBBP8,RADX,REV3L,GTDC1,PRIMA1,LGI2,ROBO2,ELP2,NEK11,FBXW7,ZC3H14,GLDN,RPS20,KCNIP3,CLIP1,ZNF331,SATB1,SCN2B,SCN8A,TNFRSF19,PEAR1,PUF60,PPM1E,FBXO11,NUBPL,WDR37,BTBD3,WDR47,SLC6A8,KDM4D,SLC8A1,ARHGEF40,SLC11A1,SLC12A2,NAPB,TET1,CPEB4,ZNF667,TTC17,SNAP25,SNCA,MBD5,USP33,PDZD2,SP4,UHRF1BP1L,KDM4C,CDK19,ZBTB43,TSPYL2,RBM26,NFASC,SEPT8,DIP2A,STAC2,NSFL1C,SYN2,TACC1,MTCL1,EXOC7,ATMIN,TCF4,CUX2,ZEB1,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,ITGB3BP,AP4E1,TIAM1,TMPO,RIMBP2,RGMB,SMUG1,TRPS1,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,WIPF1,CLDND1,KCNT2,LYPD6,ZBTB38,EMSY,SLC38A1,EVI5,STOX2,PRDM8,SLC17A7,FAM13C,FZD3,UBE3B,FBXO36,FAM219B,NLRP3,TTC7A,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-miR-657:mirSVR_lowEffct hsa-miR-657:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-98 6.09E-95 1.71E-97 1.57E-96 256 1474 "DGCR6,METAP1D,KLHL32,RNF157,USP31,AP2A2,OSBPL1A,CC2D2A,AK2,SMIM17,SEMA6A,ALCAM,LTBP4,FAM135A,EPB41L5,TNRC6C,ARSE,CDK13,SLC4A4,N4BP2L1,DPY19L3,ADAM23,BCL7A,KSR1,BMP7,ARHGEF7,AP1M1,CACNB4,THSD7A,KALRN,PTBP2,CAMK2A,CH25H,RUNX1T1,RGN,MAGI1,DLGAP1,CFL2,SRSF11,SOCS6,CHN1,RAB33A,NRXN3,CLTC,CNR1,PCYT1B,ARMC8,ZNF521,C2CD2,CRY2,ANKRD44,NCOR1,CS,MROH8,CSF1,RGS6,CSF2RA,OSBPL3,SIPA1L1,APPL1,PUM1,DCAF4,RUBCN,MATR3,KIAA0586,DGKB,GIT2,ARMCX4,PITPNC1,ARMCX2,B3GAT3,KLHL3,KIF19,DTNA,AASDH,EDNRA,ANKRD46,HEYL,RASA4,EIF5,PCOLCE2,DCTN4,EPB41,ERBB2,NCALD,ETV1,RRAGB,EXTL2,F5,CLVS1,NSRP1,FGF11,SUCO,SLC37A3,NELFCD,KHDRBS3,CELF1,CSPG5,SARAF,SULT1C4,SESN1,COPS8,GLI2,ZNF638,GPD2,PRUNE2,TDRKH,LPAR4,PCLO,GRIA2,BTN2A1,COQ10A,GSTM5,BVES,AP4S1,SOX21,LINGO1,FAM107A,SLC2A6,HAS2,TOX2,PACSIN2,FRMD3,TCEAL6,MSL1,FAM95B1,MYLK2,KCND2,GATD1,KIT,STXBP5,L1CAM,LAMP2,NCOA7,SMAD1,PIK3AP1,MAP4,MAPT,MATN2,MBNL1,MBP,MID1,AFDN,BLOC1S2,PTOV1,N6AMT1,HNRNPM,NME4,CNOT4,SLC11A2,NUCB2,LOC100128398,OPRL1,PCDH8,PFKFB2,PFKFB3,ZNF655,FAM218A,STRN3,LRP12,RETREG2,EPB41L4B,MINDY2,PPM1B,RASGEF1B,PRKACB,PKIA,PRPSAP2,CNNM2,NDUFS7,BCAS3,VPS13C,BDNF-AS,PTK2,PTPRO,TMEM255A,KHDRBS2,ZDHHC14,TRIM68,GTDC1,PBRM1,ZFHX4,SETD5,C12orf49,GSTCD,CCDC102B,NEK11,ARMH4,GLDN,DGLUCY,ATXN7,TNFRSF19,GALNT10,SUPT20H,KIF27,TRA2B,FBXO11,PEX26,PPP4R3A,KANSL3,LGI3,CPEB4,SMARCC2,ANKRD36,MBD5,TMCC1,MYO16,FNBP1,ERC1,LHPP,SAMSN1,CEP68,VPS13A,SYT1,ANKRD28,PJA1,CAMTA1,MLST8,AGTPBP1,IQCE,TPCN2,TCF12,SZT2,SYNE1,FAM189A1,SIRT1,ZFPM2,ARL10,PRRT1,TPM1,SMUG1,TRIO,TRO,TRPS1,CLHC1,RPL7L1,UBE2H,UGT8,PLPPR2,WIPF1,ZNF24,REEP1,FSTL5,ZNF189,SPIRE1,EMSY,CADM2,MDH1B,URM1,SLC17A7,DNAH10,RTN4,CASC15,IFT88,SOCS4,ST8SIA2" MicroRNA hsa-miR-1244:mirSVR_highEffct hsa-miR-1244:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-98 6.27E-95 1.75E-97 1.61E-96 248 1383 "KCNH8,GALNT13,PLEKHH1,PWWP2A,MTUS1,KCTD16,C1QTNF3,CEP126,ABCD2,ARHGAP20,PCDH10,AMT,DPP10,ANK2,CCDC146,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,LGR5,TMEFF1,ZBTB10,CFLAR,SYNJ1,SCAPER,MTMR2,IL33,CALB1,ZNF555,CALM1,CH25H,CD38,MAGI1,NUMBL,SRSF11,FOXN3,MS4A7,B4GALT6,NDST3,PLAA,CLCN3,QKI,CNTN1,ARMC8,ABI3BP,COX4I1,IGDCC3,FAM171B,SEC31B,ENTPD4,NCOR1,LRIG1,PDE4DIP,PUM1,USP6NL,CCDC144A,ARHGAP24,HDAC4,ZFYVE16,DAPK1,GIT2,PITPNC1,HEPH,ALKBH8,WDR20,DMD,DYNC1I1,GOLT1B,AASDH,EBF1,WDPCP,EDNRB,FCF1,SEMA3D,FAM13A,ASB3,TENM1,PLEKHA1,TMEM35A,CALCRL,PAN3,GPHN,CEP85L,EYA1,F8,FAM198B,FCGR1A,FCGR1B,ZSCAN30,FGF1,POLK,SUCO,JKAMP,HVCN1,KHDRBS3,OGA,MEGF11,CHL1,GABRB3,GABRG2,GALC,MTHFD2,DISC1,KIAA1841,MSTN,PPARGC1A,GNAL,FERMT2,LNX1,GPD2,GPR12,GPR37,ZNF496,CIT,SOX21,PSIP1,GUCY1B1,ZHX1,MIER3,VSIG4,CELF5,SMAP1,NME9,ITPKB,METTL21A,KCNH2,KCNN2,KCNN3,KPNA5,HECTD2,MAP6,MARK1,MBNL1,MEIS2,XRRA1,ADAM22,MYO9A,NCF2,NF1,NOVA1,PCSK5,GPR85,FAM98B,ABCB1,PIK3C2A,FAM218A,CCSER2,PLIN1,PMP22,TRHDE,STRN3,SH3KBP1,MINDY2,PPP2R5E,PPP3CA,PRKAB2,PRKCB,MAPK4,MAPK9,DIRAS2,VPS13C,WBP1L,SNRK,CNTLN,MTMR10,SPDL1,PTN,TMEM260,ZSCAN32,PTPRN,ZNF615,QDPR,TMEM255A,FAT4,OXR1,RET,GTDC1,RGS4,NUDT11,EXD2,CCDC102B,RPL15,ADAL,RYR3,CCDC112,ATXN7,FNIP1,FBXO11,FNDC3A,FHOD3,CCDC88A,GKAP1,USP33,DOK5,KDM3A,ZNF423,DBNDD2,CLASP2,POGZ,ITPRID2,LARP4,NKAIN2,SS18,ERBIN,NXT2,SEPT8,DIP2A,KLHL7,PLCB1,COBL,ANKRD12,FAM208A,TBCEL,KLHL4,ATMIN,SATB2,SIK3,DICER1,TMPO,C9orf85,SYNPO2,TRIO,STXBP4,SSBP2,CLHC1,UBE3A,VLDLR,CLDND1,ZFP37,ZNF711,MICU3,KCNT2,TRIM9,ATP6V0E2,ZNF138,ZNF225,EMSY,DNALI1,EVI5,AMN1,SMIM8,RNF170,FXR1,IFT88,NETO2,DPF3,CPNE4,FAM198A,SENP7" MicroRNA hsa-miR-4309:mirSVR_lowEffct hsa-miR-4309:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-98 6.30E-95 1.75E-97 1.62E-96 266 1591 "CLK4,XKR4,ADD2,KCTD16,KIAA1324,OSBPL8,TAOK1,ANK2,FGD2,PHF12,APBA2,CDC14B,SEMA4G,MADD,ARNTL,LINC00173,PCDHGB4,NUMB,SLC4A4,EIF4G3,ATP2A2,ATP2B2,DOCK11,ADAM15,BACH1,ADGRB2,RGS9,SYNJ2,SCAPER,GPC2,CA4,CA12,PTBP2,CAMK2G,SPAG9,NFS1,CBLN1,METTL6,CD86,SYNGR3,TAOK2,NRXN3,CLTC,MAP4K4,LY86,AKAP6,RCHY1,SMARCAL1,MYRIP,SEC31B,PREPL,AKAP12,CSF2RA,CSNK1E,FAM169A,MYADM,ARHGAP32,EARS2,DAPK1,DNAL1,DGCR5,POM121,SGSM2,SLC25A18,ARRDC4,DNM1L,PHC2,FCF1,KLHL5,CELSR3,FAM13A,SUGP2,EGFR,IRAK4,USPL1,TUBD1,ETV1,TLR7,ADGRV1,TMEM132C,ZSCAN30,PPP1R1B,GTF2IRD2,FHL1,POLK,SEMA4D,PSD2,NOP56,WDR83,CAMKK2,ATP6V1H,CELF1,SDCBP2,ZNF44,GALNT15,DENND2A,ZNF274,DISC1,SULT1C4,MSTN,GGT5,CRCP,DBF4,GLYR1,LNX1,GPD1,GPD2,PRUNE2,GPR12,STON1,PLPP7,GRIN2D,GSTT2,GUCY1B1,FAM222A,UBE2QL1,FRMD5,AGBL5,NEGR1,NKD1,INPP5B,ITGAM,SLC35G1,KCNB1,KCNJ16,GATD1,LINC00634,IPO5,SFXN5,SYTL4,PIK3AP1,CLEC18A,MAN2A2,CHIC1,MEIS2,KITLG,MN1,MPP2,PTOV1,MYO9A,CCDC13,NF1,NOVA1,SMIM11A,NTRK2,OCRL,OGG1,GLIPR1L2,PCDHGC3,PCSK5,PDE1C,NALCN,CCSER2,ZNF426,PLXNB1,SDK2,LRRN3,PRKCB,GRAMD1C,DIRAS2,NCR3LG1,ZSCAN32,PTPRE,ZSCAN2,NWD1,ROGDI,OXR1,RASGRF1,TRIM68,REV3L,ZNF532,SUGCT,TMLHE,KLHDC8A,ARMC5,CARF,ROBO2,ELP2,KIAA0895L,SGSM1,LRRK2,PTGR2,KCNIP3,DGLUCY,MAPK12,SEMA6D,CSRNP3,SCN2B,SCP2,TNFRSF19,GALNT10,SUPT20H,SH3GL3,AMBRA1,WDR47,FAM214B,KANSL3,PKNOX2,SLC6A11,ARHGEF40,SLC14A1,BTBD7,CDK5RAP2,SMARCD3,MYH15,ANKRD36,SNCA,FAM219A,DOP1A,ZSWIM8,NMNAT2,ARHGAP26,NFASC,PBLD,CLSTN2,ZC3H4,SYNE2,MTCL1,FAM208A,KLHL4,WSCD1,DMXL2,CUX2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PCDHB3,PCDHA5,FRYL,RNF216P1,PMS2CL,SLC44A1,THRA,CHST5,RUNDC3B,TRO,TRPS1,PPIL6,TSN,TTTY15,RPL7L1,VIPR2,VLDLR,RICTOR,ZNF708,TCEAL7,DPYSL5,MEIS3,SLC30A4,CADM2,SIGLEC10,PCBP4,FAM13C,MARCH8,DPF3,FAM198A" MicroRNA hsa-miR-671-5p:mirSVR_lowEffct hsa-miR-671-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-98 6.75E-95 1.88E-97 1.73E-96 272 1663 "RALGAPA1,SYS1,ACTN1,ADCY6,ADD1,ADD2,AP2A2,KLHL13,PCDH19,HACE1,SYT13,PDZD4,EP400,PI16,PPFIA4,PHYHD1,AQP6,CASK,CADPS,NUMB,SLC4A4,RIPK1,ADAM15,BARD1,MPDZ,IL33,CA4,CABP7,KALRN,HAP1,CAMK2G,PRC1,SCARB1,SYNGR3,DGKI,ARHGEF2,NOG,B4GALT6,CNOT8,CPNE6,HECTD1,FAM149A,SLC4A8,ZNF385A,CRMP1,ANKRD44,ABCG1,CS,SNCAIP,CSF2RA,ARHGEF10,CSNK1G3,SIPA1L1,KIAA0040,HDAC9,ZNF337,IST1,IP6K1,ELMSAN1,ZBTB24,MFAP3L,RUSC2,KLHL3,GSDME,RHOBTB1,SNAP91,SV2B,EXOG,SLC29A4,DOCK2,DTNA,ECM2,AASDH,SNX29,EDN3,KLHL5,CELSR3,EBI3,C3orf18,EMX2,VPS13B,EPB41L2,GPHN,STX2,F5,CLVS1,FCGRT,KAT8,FGF13,TMEM164,FHL1,MEX3B,HPCAL4,IQCG,FOXO3,SYT3,EFCAB2,CAMKK2,ERGIC3,KHDRBS3,CGREF1,OGA,GHDC,HIGD1B,TMEM8B,C15orf41,INPP5K,GATM,TUBA8,CYP46A1,ADAM28,GGT7,WDFY3-AS2,PRRC2B,GPD1,GPD2,TDRKH,STON1,GRIA2,PLCD4,ADAMTS13,GSTM5,FAM107A,SLC2A6,ATOH8,ZDHHC15,LRRC75A,CELF5,SMAP1,NKD1,KIAA1755,ZNF678,ITGA7,ITGAM,C2CD4C,SLC35G1,KCND1,KCNQ3,KHK,KIF5A,LINC00634,LAMP2,STMN1,ZFYVE27,CHST6,DBNL,SAMD5,MXI1,LYRM9,MYO7A,MYO9A,NACA,NFYA,DNHD1,NTRK2,NTRK3,TBC1D25,IGSF11,LOC100128398,PDE4D,ZNF655,PLCB2,SLC25A23,MAPKAP1,SEPT4,MBOAT7,SH3KBP1,PPP3CA,MAPK10,DIRAS2,BCAS3,PIGG,ELOVL2,TMEM260,ZSCAN32,PTPRE,RASGRF1,RASGRF2,RDX,FIGN,RGS3,EXD2,CARF,ROBO1,MRAP2,SNX22,NEK11,FBXW7,BAALC,GLDN,ADAL,STK32B,MAP6D1,EMID1,HSD11B1L,CASC3,SH3GL3,FRMPD1,ABLIM3,SLA,SLC2A5,SLC6A8,SLC9A5,TRIM67,SLC11A1,ELMO2,SMARCC2,MYH15,RCOR3,ANKRD36,SNRPN,KDM4B,USP33,FAM219A,ZSWIM8,PEG10,NFASC,CLASP2,SSTR2,SEPT8,ADHFE1,SYNE2,ARHGEF9,SYN1,SYPL1,TACR1,CAMTA1,MLST8,EXOC7,TBCEL,IQCE,SMG6,NEU4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,TMEM9,TLR4,KAT6B,NPL,WBP2,AMACR,TRPM2,TSN,LINC00689,RBFOX3,GUSBP1,SLC47A2,ZNF708,TRIM9,NDRG4,LYPD6,AMZ1,EML6,DPYSL5,SPIRE1,DHX33,PRTFDC1,FIP1L1,PCBP4,PDSS2,RGS7BP,RTN4,UBE3B,FBXO36,FAM219B,JPH3" MicroRNA hsa-miR-1275:mirSVR_lowEffct hsa-miR-1275:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.82E-98 1.02E-94 2.82E-97 2.60E-96 286 1837 "VWA5B2,DGCR6,ASIC1,EMILIN3,RNF157,PLEKHH1,UNC5A,KLHL13,PCDH19,WDR35,C1QTNF1,C1QTNF3,SEMA6A,UNC79,BEGAIN,DOC2A,AMPD2,AMPH,DPP10,LRCH2,CCDC146,PKP4,UPRT,APOC2,AQP6,SEMA4G,ARHGDIA,ARRB2,MARCH3,NCOA1,RASL11B,ADGRB1,ADGRB2,BCHE,RGS11,HCN2,CFLAR,LDHD,CASTOR3,GYG2,CACNA1I,C5,GPC2,WASF1,CA4,CALB2,CABP7,KALRN,HAP1,PRC1,ZNF501,METTL6,SYNGR3,ENTPD2,LRRFIP1,LOC730101,MAGI1,QKI,HOMER3,PICK1,LETMD1,AKAP5,SLC4A8,MYRIP,SEC31B,CREM,SH2B1,HINFP,CLIP3,FAM169A,PITPNM3,PLCXD3,GPSM1,MYADM,ARHGAP32,SNPH,GIT2,DBN1,DCTN1,RUSC2,SGSM2,WDR20,GRIN3A,DNAH9,SLC12A6,DPH1,DTNA,ABCC5,AASDH,EBF1,CNNM1,HEYL,SEMA3D,TMTC1,PHF20L1,SUGP2,EGR3,RASA4,CERCAM,EIF1,MTSS1L,MRVI1,EZH1,CLVS1,ZNF461,SCML2,ST3GAL6,KAT8,PPP1R1B,FGF11,BAIAP2,AMOTL2,SUCO,IP6K2,DCTN2,CAMKK2,ZNF605,CGREF1,RAPGEF6,SIGLEC8,SEPT9,ALDH1L1,CYP46A1,ZNF276,TTBK1,TXNL4A,SPIN1,GLYR1,AIFM3,STARD3,GNAO1,GPR12,STON1,STMN2,ATP2B1-AS1,PLCD4,ADAMTS13,GRIK5,GRIN2C,ATE1,KAT7,ATXN2L,ARHGAP36,AGBL5,IDH3B,C2orf72,IGF1,KNDC1,SLC6A17,INSM1,KCNH2,KHK,TTYH2,LIMS1,NCOA7,PIK3AP1,MID1,GIT1,DBNL,MYO6,MYO9A,NBL1,CCDC13,NF1,ALDH1L2,NFIX,NME4,VWA2,NUCB2,PAX6,PCSK5,CDK18,PDE4A,PDE1B,GNG2,PGAM2,PLCB2,SLC25A23,NECAB2,POLR2F,FSD1,PPP5C,VSTM2L,PRKAR1B,DIRAS2,VPS13C,DEF8,TMEM260,CASTOR1,PTPRN,RIPOR1,NKAIN1,ACSS3,ZNF793,IQSEC3,SUSD4,ZDHHC14,GAL3ST4,RGS3,RGS12,PRIMA1,CARF,PNMA8A,GLDN,SGSM1,NCBP3,DGLUCY,SBF1,PEAR1,FAM102A,ARX,FERMT1,WDR37,EPN2,SLC8A1,SLC11A1,CPEB4,SMARCC2,CDK5RAP2,SNRPN,ZSWIM8,UHRF1BP1L,SPTB,POGZ,NKAIN2,SSPO,ST5,STAC2,KANK1,SULF2,SEPT3,RHBDL3,SYN1,SYN2,TACC1,CAMTA1,ATMIN,WSCD1,DMXL2,SZT2,NAT16,FAM189A1,NSD1,TNS2,ARHGAP9,HIF3A,CYB561A3,RNF216P1,DICER1-AS1,THRA,RIMBP2,CSMD1,KAT6B,ZNF346,TRPS1,NUTM2A,DCBLD1,SLC35A4,UBTF,GORASP1,PLEKHH2,VIPR2,VLDLR,TBC1D15,TSPAN11,CLIP2,WNT7A,TRIM9,ATP6V0E2,ZNF70,CELF4,TMEM198,ZSCAN26,LAMP5,NT5M,EVI5,LINC02210,ADAMTS9,SEMA3B,URM1,SLC17A7,ITM2C,MPPE1,EPM2A,AMN1,ADAMTS10" MicroRNA hsa-miR-21*:mirSVR_lowEffct hsa-miR-21*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.15E-98 1.20E-94 3.33E-97 3.06E-96 272 1667 "RALGAPA1,RNF157,KIAA1211,ESYT2,BEND6,AP2A2,INTS2,OSBPL1A,TAOK1,SMIM17,SEMA6A,PCDH10,PKP4,FAM131A,CPNE5,ZFYVE28,TMEM108,SLC4A4,EIF4G3,TTLL9,BBS2,BCL7A,GPR146,DST,MYRF,CACNB4,CAMK2A,CHN2,CNOT8,FBXO7,MAP4K4,FAM149A,COL4A5,C2CD2,RBM39,CRMP1,ANKRD44,GDA,CSF1R,LRIG1,SUSD5,IPCEF1,PLXNA4,ERC2,GREB1,PUM1,GPRASP1,LIN54,DGKG,SCRN1,IP6K1,ARMCX4,YTHDC1,KIAA0753,POM121,RHOBTB1,SV2B,CHRDL1,RAB39B,DMPK,CDON,DPP6,TOM1,ABCC5,FAM13A,SUGP2,APH1A,MBNL2,KMT5B,EGR3,EPB41,EPHB1,ENPP6,RABEPK,STX2,SCML2,DLC1,FECH,MED12L,GTF2IRD2,POLK,SUCO,PCYOX1,SYNCRIP,FOXO3,EVL,ANKFY1,HVCN1,ATP2C1,ZNF605,ERGIC3,KHDRBS3,NSG1,MPP6,MEGF10,CHL1,GALNT15,GABRB3,GAD1,RAPGEF6,MTHFD2,C15orf41,DISC1,INPP5K,GFRA2,GHR,PPARGC1A,ZNF638,KDM2B,LUZP2,ADGRA3,PRUNE2,GPR12,PCLO,GRB10,DIDO1,GRM2,ZBTB49,PACSIN2,HLF,ACOT7,GABARAPL2,SYNPO,ZDHHC15,CELF5,SMAP1,ZNF546,GAREM2,IL6R,KCNB1,KCNJ5,CREG2,KIF2A,KIT,IPO5,CYP27C1,SYTL4,PACRG,CLEC18A,MAP2,MARK1,MAT2A,MATN3,CHIC1,MEIS2,MID1,MMP16,SAMD5,N6AMT1,MYO6,MYO9A,NCAM2,NF1,DNHD1,NRCAM,NTRK2,NTRK3,CLDN11,CDK18,GNG2,PFKFB4,CCSER2,RETREG1,XRN1,KCTD15,PURG,PRIMPOL,PNMA3,STRN3,RETREG2,MINDY2,LRRN3,PPP2R5E,PRKACB,PKIA,HYDIN,MASP1,DEF8,SNRK,TMEM104,QRICH1,WDR25,CNTLN,PTK2,PTPRE,TUG1,TMEM231,RASGRF1,ZDHHC14,RET,RFX3,RIC8B,ROBO1,CCDC25,RORB,SNX22,NEK11,PTGR2,ABCA11P,HUNK,ST6GALNAC6,ATAT1,RTN1,RMI1,LRFN5,SCN8A,PPM1E,CPEB3,CNKSR2,NUBPL,WDR47,SLC9A5,KBTBD4,SLC12A2,SLC12A4,SLC14A1,ELMO2,BTBD7,CPEB4,COA1,DMRTC1,SPP1,PBLD,LARP4,NKAIN2,MPRIP,ZSCAN29,STXBP1,ZC3H4,PRRC2C,VPS13A,DNAJC9,SYN2,TACC1,KLHL4,SATB2,CUX2,TCF12,USP22,PUM2,ARHGAP9,ZFPM2,ZMAT3,ZNF106,CDH22,ARL10,HEY1,TLR4,KAT6B,WBP2,SMUG1,AMACR,TSC1,TUBB1,FLRT2,RICTOR,ZBTB14,TRIM9,LYPD6,ZBTB38,ZNF154,REEP1,FSTL5,ANKS1B,ADAMTS9,MDH1B,UBE3B,KAT6A,CASC15,FAM219B,ADAMTSL3,ST8SIA2" MicroRNA hsa-miR-4287:mirSVR_lowEffct hsa-miR-4287:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-98 1.61E-94 4.44E-97 4.09E-96 279 1754 "KCNH8,GALNT16,PWWP2A,ADRA1D,BEND6,AP2A2,KLHL13,PCDH19,WDR35,AK2,ADGRF5,SEMA6A,PCDH10,PDZD4,APBA2,KCNAB2,AQP6,SEMA4G,SPTBN4,ARRB2,TTLL9,DNAJC27-AS1,NRP2,BTK,SCAPER,CACNA1I,CFAP410,CA12,CACNA1B,CABP7,CALM1,KALRN,CAMK2B,CBR1,MTMR7,UBE2L6,CFL2,FOXN3,CHN2,RAB33A,FBXO7,QKI,TMEM184B,SRP14-AS1,LY86,ARMC8,SUMF2,AKAP5,ZNF521,CLOCK,ANKRD44,CSF2RA,SEC24C,LRIG1,ARHGEF10,CSNK1E,FAM169A,DZIP3,PLCXD3,CCDC144A,HDAC9,AIF1L,SPATA2,JAKMIP2,ZBTB24,MFAP3L,KIAA0319,SNAP91,NYAP1,DNAH9,RPS6KL1,NR1D2,CDON,ACOT8,ABCC5,EBF1,EDN1,HEYL,FSD1L,CELSR3,PHF20L1,APH1A,EIF1,EMX2,ERBB2,PIPOX,RASL12,MRVI1,CLVS1,RPS6KC1,ACSL4,FCGR3A,ZNF589,PRKAG2,FOXF2,PCYOX1,FLT1,SLC37A3,NBEA,RASL10A,KHDRBS3,NSG1,TVP23A,OGA,GALNT15,SEPT9,INPP5K,GCK,GCNT2,CYP46A1,GFER,GGT7,GLYR1,TOX3,ZNF638,KDM2B,RAB40B,GPD2,TMEM121B,PSIP1,RNFT2,ATXN2L,MIER3,HLF,AGBL5,ZNF491,USP51,CPT1C,SMAP1,EID2B,IRF8,FAM95B1,C2orf72,IL12A,JAK2,KCNH2,KCNK3,KIF5A,CLEC18A,MAN2A2,MAP6,MAPT,MAT2A,MBD1,ADAM11,MEIS2,MGAT3,XRRA1,MN1,SAMD14,LYRM9,MYO7A,MYO9A,NEXMIF,NF1,NOVA1,DNHD1,SLC11A2,LOC100128398,PCDH9,PFKFB3,PFKFB4,TMIE,ZNF655,FAM216A,PRIMPOL,PNMA3,PMP22,TATDN3,PPP3CA,PRKACB,GRAMD1C,HYDIN,SNRK,WDR25,BDNF-AS,PTPRB,PTX3,CEP97,RAD51D,ZNF793,NWD1,RADX,ZDHHC14,ZMAT4,RGS3,RGS12,KIF7,DCUN1D2,SETD5,HUNK,KCNIP1,CLIP1,RXRA,ZNF331,DGLUCY,CSRNP3,FNIP1,GALNT10,SH3GL3,FRMPD1,ARX,ANKRD6,WDR37,PPP4R3A,SLC6A8,SLC11A1,SLC14A1,NAPB,BTBD7,ATF7IP,CPEB4,SMARCC2,MYH15,KIF13A,SNRPN,FAM219A,SOX11,IZUMO4,KDM4C,PEG10,ZNF423,DDN,NFASC,CAMTA2,SS18,PHLDB1,ARHGEF9,VPS13A,PLCB1,TACR1,MTCL1,PJA1,CAMTA1,TAL1,FBXW11,KLHL4,WSCD1,SATB2,TRIM2,RPGRIP1L,TCF12,SYNE1,PHF24,PCDHB7,GPRIN3,SIK3,RNF216P1,FAM200B,SIRT1,AP4E1,ZNF106,ARL10,TLR4,RUNDC3B,CLHC1,VSNL1,TSPAN11,XPO1,PCDH20,MICU3,CELF4,ZBTB38,FSTL5,TMEM198,ZNF189,PCBP1-AS1,PRDM8,HPS4,CIAPIN1,WNK3,UBE3B,KAT6A,FAM219B,IFT88,DPF3,ST8SIA2,GAN,SENP7" MicroRNA hsa-miR-942:mirSVR_highEffct hsa-miR-942:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-98 1.62E-94 4.45E-97 4.10E-96 285 1828 "AS3MT,NCKAP5,KDM5D,ADCY6,GALNT13,ADD1,KIAA1211,FAHD2CP,HECW2,CC2D2A,ADGRF5,SPOP,ARHGAP20,CARNS1,UNC79,LCORL,APC,EPB41L5,BCAS1,PPFIA3,SPTBN4,STK33,INSYN2B,SLC4A4,ADAM23,MPDZ,SEC11C,PROM1,DST,SCAPER,LURAP1,KALRN,CAST,CBR1,ZNF501,CBS,KRIT1,CCNH,SLC16A4,MAGI1,NOG,SRSF11,CLCN3,HECTD1,AKAP6,COL4A5,COL11A2,SLC4A8,SMARCAL1,IGDCC3,NECTIN3,SLC35F1,FAM171B,CDC42BPB,SH2B1,GDA,MROH8,SNCAIP,CSF2RA,SEC24C,SOCS5,VAC14-AS1,PDE4DIP,ERC2,ZSCAN23,DCAF4,BOC,TCAF1,ZFYVE16,LONRF1,TM9SF4,LIN54,MATR3,DGKB,AIF1L,ARMCX4,JAKMIP2,ZBTB24,HEPH,DDX46,SPOCK3,WDR20,CHRDL1,EXOG,DMD,DNM1,CPEB2,DMTF1,EDN3,FCF1,FRY,YAF2,FAM13A,PHF20L1,KMT5B,EGR3,RASA4,TENM1,PAN3,IGSF6,ZNF391,CDKL3,DNAJC27,HSPA12B,NRN1,CLVS1,FAM198B,RPS6KC1,DLC1,FGF1,FGF12,FGFR1,FLNC,ATP13A4,ZNF605,ST6GALNAC3,STAU2,GALNT15,GABRG2,TRAF3IP2,FAM120B,ZNF559,DISC1,CPLX1,WASHC2A,PCDH17,GHR,CRCP,TCERG1,HPGDS,GLI2,TNRC6A,GNAL,GPD2,STMN2,GRIA2,C1QL4,CLASRP,FAM19A2,AP4S1,SOX21,LINGO1,RNFT2,AGBL5,HSF2,CELF5,MSL1,IDH3A,ZIC5,LRRCC1,IL6R,INPP5B,NME9,ITGAM,KCNJ16,LIMS1,PACRG,ZFYVE27,MBD1,MEF2C,MEIS1,MEIS2,AFDN,GIT1,MSI1,PTOV1,MYO9A,ZNF862,NF1,NOVA1,SMIM11A,NTRK2,NTRK3,PCDH9,PCSK5,CDK18,PDE3A,GPR173,PFKFB2,PIK3C2A,SNX10,XRN1,PLCL1,PCDH18,ZNF426,MAGEL2,ING3,SEPT4,POLG,PPARA,PPP1R1A,PPP2R2C,LRRN3,PPP2R5E,KANSL1,PRKACB,EPDR1,MAPK10,HYDIN,SNRK,WDR25,BDNF-AS,PTPRD,EML5,PTPRE,PTPRG,CCDC40,RASGRF2,NUDT11,CCDC82,EXD2,C12orf49,ROBO2,RORB,YY1AP1,ABCA11P,ATAT1,ZNF354C,RYR3,ATXN7,TNFRSF19,FNDC3A,ANKRD6,FAM81A,SEPHS1,BTBD7,SLC22A4,RCOR3,ANKRD36,MBD5,KIF13A,SNRPN,PDZD2,DOK5,UHRF1BP1L,DBNDD2,PBLD,POGZ,NXT2,STXBP1,NSFL1C,NECAB1,PLCB1,TMEM150C,FBXW11,ATMIN,WSCD1,ZEB1,USP32P1,FRYL,RNF175,RNF216P1,TEK,DICER1-AS1,AP4E1,NR2E1,ERCC6L2,RIMBP2,TPM1,METTL3,ELP5,TRIO,AMACR,TRO,TSN,TTC3,RPL7L1,UBE2H,LAT2,PCDH20,ZNF32,ZNF70,CELF4,REEP1,ANKS1B,UPF3A,SLC17A7,FIP1L1,EPM2A,FAM13C,SMIM8,NHSL1,NETO1,DPF3,SENP7" MicroRNA hsa-miR-220b:mirSVR_lowEffct hsa-miR-220b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-98 1.65E-94 4.52E-97 4.16E-96 287 1853 "ABCF1,AS3MT,METAP1D,PLEKHH1,ADORA1,KIAA1211,OLMALINC,TBC1D14,SEMA6A,ALCAM,PCDH10,APBA2,KCNAB2,FAM131A,CPNE5,PCDHGB4,SLC4A4,ATP2B2,SLC2A11,N4BP2L1,BCL7A,NRP2,GPR146,WASF1,BAIAP3,CACNA1B,CAMK2G,VXN,CH25H,RHBDL1,ARHGEF25,SYNGR3,C1orf52,CDH2,DCLK1,LRRFIP1,MS4A7,CPNE6,FBXO7,IGLON5,ARMC8,SUMF2,AKAP5,SLC4A8,COX4I1,SMARCAL1,SH2B1,ANKRD44,NCOR2,GDA,ABCG1,SNCAIP,ARHGEF10,CSNK1E,DZIP3,KIAA0040,ERC2,GREB1,RUBCN,HDAC9,KATNAL2,DCAF8,TMEM170A,IP6K1,GIT2,HEPH,KLHL3,GUCD1,PLPPR4,SPOCK3,SGSM2,DLX1,EXOG,DNM1,HS3ST2,DOCK2,DPH1,ACOT8,DRP2,DTNB,TOM1,ABCC5,EBF1,SNX29,EDN1,PHC2,PHF20L1,IRAK4,TENM1,EPB41L2,ZNF549,MRPL37,ANKMY1,MRVI1,ACSL4,TAOK3,FCGRT,FER,FGF1,FGF12,FGFR1,PRKAG2,IP6K2,RGPD5,FOXO3,EVL,NOP56,ST6GALNAC3,NSG1,DLL3,SARAF,TVP23A,ZMAT1,GABBR1,GAD1,GHDC,DISC1,ACSS1,CPLX2,KIAA1841,GCNT2,SULT1C4,GGT7,TXNL4A,GLI2,MSL3,ZNF638,LILRB4,TMEM121B,GRIN2C,PRDM5,GSTM5,KAT7,HLF,VSIG4,ZNF491,MSL1,FAM95B1,IDH3B,ZNF181,RBPJ,NME9,ITGAM,ITPKB,JAK2,HECTD2,MAPT,MATN2,SCAMP5,XRRA1,GIT1,BLOC1S2,PTOV1,MXI1,PCBP3,SLC11A2,NTRK2,NTRK3,SETD4,LOC100128398,ZNF713,OXTR,PCDHGC3,PFKFB2,ZDHHC8,TMEM38A,ZNF426,ANKRD16,LRP12,MAGEL2,ING3,FA2H,PCDHB17P,PPP2R2C,LRRN3,PPP3CA,MAPK4,HYDIN,SAMD9,VPS13C,PIGG,CNTLN,PTPRG,PTPRH,C1orf109,NWD1,ZNF493,OXR1,GTDC1,PBRM1,CYB561D1,ROBO1,ROBO2,PCMTD2,SGSM1,ABCA11P,SCN8A,FNIP1,GALNT10,SCAF8,FERMT1,NLGN1,DZIP1,SLC2A5,EPN2,ARHGEF40,CCDC88A,NAPB,BTBD7,LGI3,ZNF667,SMARCA4,MAST1,CDK5RAP2,RCOR3,IFT122,ANKRD36,INAVA,SNRPN,KDM4B,FAM219A,PDZD2,ZSWIM8,UHRF1BP1L,ZBTB43,RBM26,LHPP,CAMTA2,LARP4,SS18,ERBIN,DIP2A,ADHFE1,SYNE2,EXOC7,FAM208A,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,C18orf54,ITGB3BP,CDH22,ARL10,NEIL2,TRPM2,RPL7L1,PLEKHH2,BCL2L13,MGAT5B,CCDC14,WIPF1,LGI4,ZIC1,AGMO,ZNF74,LYPD6,TMEM237,AMZ1,ZFAND5,LINC02210,PRDM10,HPS4,SIGLEC10,URM1,AMN1,FZD3,TMEM63C,FXR1,LAS1L" MicroRNA hsa-miR-124-3p.1:TargetScan hsa-miR-124-3p.1 TargetScan 4.50E-98 2.52E-94 6.88E-97 6.34E-96 239 1291 "ABR,ACHE,FMNL2,GALNT13,PLEKHH1,ESYT2,CASKIN1,PCDH19,OSBPL6,OSBPL8,AK2,ALCAM,AMPD3,LRFN1,PHF12,APBB2,CPNE5,ARHGDIA,ARRB1,CADPS,CDK13,ASPA,CHRD,ATP1A1,DPY19L3,RGS9,BCL7A,NRP2,BID,BMPR1B,DST,FUBP1,JAZF1,MYRF,LDLRAD4,CACNA2D1,CACNB4,PTBP2,ARHGEF1,CDH2,LHX2,QKI,CNN3,CNTN1,AKAP6,MYRIP,NRG2,FAM171B,CLOCK,ANKRD44,CLIP3,LRIG1,OSBPL3,IPCEF1,GALNT9,PLCXD3,ARHGEF4,PPP6R2,MYADM,ARHGAP32,GAPVD1,HDAC4,KIF26A,LONRF1,MAML1,IST1,DAPK1,AIF1L,GIT2,ELMSAN1,GUCD1,MTX3,GRIN3A,DMD,RCAN1,DTNA,E2F5,E2F6,EBF1,EDNRB,HIPK3,FSD1L,CELSR3,PAN3,DCTN4,RAB9B,CEP85L,ETV1,EXTL2,EYA1,REEP2,MED12L,FGF14,PRKAG2,PCYOX1,ANKFY1,C2orf88,MPP6,GABRB3,IQGAP2,ARFIP1,PCDH17,NTNG2,KIAA1958,KCNMB4,GNAL,GPT2,GPD2,FUT10,GPR37,GRIA2,CACFD1,GSN,RNF165,KAT7,RASSF8,PADI2,BACH2,HLF,ELOVL5,HP,NEGR1,INSM1,ITGA7,ITPKB,KCNB1,KCNK3,KCNN3,KCNQ3,KIF2A,LIMS1,HECTD2,MARK1,MAT2A,MATN2,CHIC1,MID1,PPM1L,POC1B,MITF,AFF1,ADAM22,MYO5A,MYO9A,NCAM2,ALDH1L2,NFIX,NME4,NRCAM,P2RX7,PALM,CNTN3,PCDH8,CDK18,PDE4A,PDE4B,PDE4D,GPR173,GPR85,GNG2,PIK3C2A,PLEC,PPP2R5E,MAPK4,MAPK10,MTMR10,PTPRD,EML5,QDPR,RAD17,ENOX1,DUSP15,MORC4,FIGN,RFX3,DCUN1D2,ALG9,EPHA10,CLIP1,RXRA,RYR3,SCN2B,CASC3,GALNT10,COPZ1,KIF16B,DZIP1,FAM81A,EPN2,ARHGEF40,CCDC88A,ELMO2,BTBD7,ATF7IP,EPC1,LIMCH1,PDZD2,NFASC,LMO3,CAMTA2,NKAIN2,NXT2,PHLDB1,KANK1,RHBDL3,PLCB1,ATMIN,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ARL10,NACC2,RIMBP2,RASD2,NR2C2,GORASP1,OSBP2,BCL2L13,CLDND1,REEP1,FSTL5,EML6,DPYSL5,ANKS1B,EVI5,GDPD5,ADAMTS9,NAV3,ITM2C,MARCH8,FBXO36,FAM219B,FXR1" MicroRNA hsa-miR-497*:mirSVR_highEffct hsa-miR-497*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.72E-98 3.20E-94 8.71E-97 8.02E-96 248 1393 "NDRG3,KLHL32,DPY19L2P4,TBC1D14,OSBPL6,OSBPL8,SPARCL1,SMIM17,PDZD4,DPP10,LRCH2,ANK2,LCORL,PHF12,BCAS1,PPFIA3,IGDCC4,CCAR2,TMEM108,ATP1B3,ATP2A2,ATP2B2,RNF182,ADAM23,MPDZ,FUBP1,AP1M1,CA8,CA12,SLC25A14,CD38,LRBA,SEPT7,CDH2,MAGI1,CLGN,CACNA2D2,COPB2,NRXN3,ABCG2,IQCK,SLC4A8,MYRIP,SLC35F1,SEC31B,CREM,ENTPD4,NCOR1,GDA,ABCG1,LRRC3B,PHF14,HDAC9,ARHGAP32,LONRF1,DGKB,DAPK1,TIAM2,PLPPR4,SNAP91,KIF19,NR1D2,CDON,CPEB2,DMTF1,PDCD6IP,RCAN1,DTNA,DNAJB6,ABCC5,GOLT1B,EDNRA,FSD1L,OPTN,YAF2,PHF20L1,KCTD3,EIF4G2,TMEM35A,RCAN2,EPHB1,MRPL10,EXTL2,ABCA8,FAM198B,DLC1,CEP78,GORAB,MED12L,FGF12,FGF13,BAIAP2,POLK,FOXF2,IP6K2,PCYOX1,JKAMP,STAMBP,ATP6V1H,AP4B1,FYB1,CHL1,GAD1,GALC,RAPGEF6,ARFIP1,ADAM28,GFRA2,GHR,PPARGC1A,ZNF276,CRCP,SPIN1,ZNF638,GPR12,LPAR4,CNTRL,STMN2,GRM2,ELOVL5,HNF4G,HP,SOWAHA,RBPJ,IL6R,ZNF678,ITGA7,KCNB1,STXBP5,MARK1,MARK3,MBNL1,THYN1,MYCN,NEK1,NF1,NRCAM,P2RY1,GLIPR1L2,CNTN3,DPY19L2P2,SLC10A4,GPR85,PFKFB2,SMIM7,LRP12,PSAT1,EPB41L4B,IRX1,TATDN3,PRKACB,MASP1,CNTLN,ZSCAN32,PTPRB,PTPRD,PTPRE,C1orf109,RAD17,SH3TC2,ZNF493,RADX,ERI2,RGS12,KIF7,NUDT11,CCDC82,GSTCD,MRAP2,RPL15,FBXW7,ZC3H14,RTN1,CCDC112,SEMA6D,SCN7A,SUPT20H,ZFP30,KIF21A,FERMT1,CPEB3,FHOD3,BTBD3,EPN2,WDR47,SLC6A11,ELMO2,ZFP1,RCOR3,SNAP25,KDM4C,TEX2,ATP10B,CLSTN2,LARP4,SS18,CEP68,VPS13A,PLCB1,SYPL1,TBCEL,TCF4,ZEB1,RPGRIP1L,PCDHGA11,SYNE1,DOCK9,PCDHB10,PUM2,FRYL,SIK3,CYB561A3,TEK,DICER1-AS1,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,HEY1,ASXL3,TP53BP2,SYNPO2,STXBP4,HIRA,UCHL1,USP1,CCDC14,WIPF1,CLDND1,RICTOR,XPO1,ZIC2,ZNF17,MICU3,ZNF28,FSTL5,UPF3A,SLC30A3,ZXDA,CADM2,RNF103,SLC17A7,FAM13C,MRPL47,RTN4,PHTF2,MSRB3" MicroRNA hsa-miR-29b:mirSVR_lowEffct hsa-miR-29b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.78E-98 3.23E-94 8.79E-97 8.09E-96 279 1759 "VWA5B2,ABCF1,ACADM,CLK4,NDRG2,FMNL2,ADD2,BRAP,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,CARNS1,ZFAT,CDC42BPA,LRCH2,FGD2,CCDC146,GAS7,PHYHD1,TNRC6C,USP37,SHROOM2,CDC14B,CDK10,ARHGDIG,LINC00173,MARK4,ZBTB10,DOCK11,ADAM15,MIR9-3HG,BMPR1B,SYNJ2,MTMR2,JAZF1,LDLRAD4,CA4,CACNA1A,CALM1,KALRN,CAMK2G,CARS,ARHGEF25,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,B4GALT6,CNOT8,EPS15L1,CLTC,FBXO7,QKI,SULT4A1,WHRN,AKAP5,NCOR2,CSNK1E,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,DCAF4,FAM131B,CYBB,HDAC9,KATNAL2,RIPOR2,HDAC4,IP6K1,BRINP1,ARMCX4,SPATA2,ELMSAN1,ZBTB24,HEPH,DDX46,ALKBH8,PLPPR4,WDR20,CDON,DPYSL2,ARRDC4,ECM2,ANKRD46,SEMA3D,GOLGA7,KCTD3,PLEKHA1,C8orf37,MTSS1L,ENPP6,ERCC2,NCALD,IGSF6,SPEG,MRPL37,CLVS1,POLR1B,FGFR1,HPCAL4,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,SMC2,TRIM16,STAU2,MSANTD4,ABLIM2,MEGF10,GABRG1,ERAP1,SRCAP,PCDH17,PPARGC1A,TCERG1,DBF4,GLI2,STARD3,POLL,GP1BB,GPR12,CCDC184,ATP2B1-AS1,GRB10,GRIA2,C1QL4,ADAMTS13,RNF165,GSTM5,BVES,MUM1,RASSF8,TNFAIP8L3,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,INPP5B,ITGAM,ITPKB,KCNJ16,TTYH2,LAMP2,LIFR,MAT2A,AQP11,SCAMP5,MKLN1,COL28A1,COMMD5,RTL5,NEFM,NFE2L2,NFIX,OXTR,P2RY1,PALM,PAX6,CDK18,PIK3R1,ZNF655,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,GDPD1,WBP1L,PIGG,EML5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RBBP6,RDX,TRIM68,RET,ERI2,GTDC1,RGS3,RIC8B,ZFHX4,SETD5,CARF,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,ABCA11P,RTN1,STX1B,SMPD3,CASC3,GALNT10,KIF21A,PPM1E,FRMPD1,FNDC3A,ST6GAL1,PKNOX2,SLC6A8,SEPHS1,LGI3,TTC17,MAPKBP1,MBD5,SNRPN,DOP1A,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,ZNF302,ERBIN,CEP68,STX1A,NSFL1C,ZC3H4,SUPT5H,ADAMTS17,SYN2,C12orf76,TACC1,SIN3B,NEU4,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZNF346,SYNPO2,ELP5,AMACR,TUBB1,CLEC2L,UBTF,PLEKHH2,ZNF24,ZBTB38,ZFAND5,CADM2,HPS4,GAL3ST3,TRIM16L,PARP11,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-493:mirSVR_lowEffct hsa-miR-493:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.88E-98 3.85E-94 1.04E-96 9.61E-96 270 1651 "SYS1,KDM5D,XKR4,GALNT16,CCDC85A,ADD2,BRAP,PLEKHH1,ADORA1,PWWP2A,ADRB2,AK2,AMPD3,OGT,CCDC146,MAP4K3,APC,LGR5,CDK10,PDE8B,CHRD,NCOA1,SLC2A11,TTLL9,BACH1,MPDZ,BLM,CFLAR,BMP7,SYNJ2,JAZF1,LURAP1,CALB2,THSD7A,CALM1,PTBP2,CH25H,NFS1,P2RX6,CBFA2T2,CD38,CDR1,TIGD7,CCPG1,CHN2,MS4A7,TPP1,SULT4A1,IGLON5,ARMC8,COL9A3,ABI3BP,COX4I1,SLC35F1,RBM39,ANKRD44,NCOR1,NCOR2,CLIP3,ABCG1,CSF1R,SOCS5,PDE4DIP,CCDC144A,BOC,DOCK4,EARS2,ZNF337,LONRF1,KIAA0586,DGKG,DAPK1,DNAL1,PITPNC1,JAKMIP2,KIAA0319,SPOCK3,DLX1,USP3,DOCK2,DMTF1,SLC25A18,ACOT8,ECM2,E2F5,EDN1,FAM13A,COPS4,ELN,C3orf18,TMEM35A,RASGRP2,ENPP6,IGSF6,CLVS1,FAM198B,SH3YL1,FCGR1A,FCGRT,FER,OLFM1,POLK,SUCO,SYNCRIP,SLC37A3,EFCAB2,WDR83,PDLIM5,STAMBP,CAMKK2,CELF1,MPP6,BRSK1,FYB1,HRASLS5,CHL1,GABRB3,IP6K3,ACSS1,GDF9,GPR162,USP19,STARD3,GNG4,PRUNE2,FUT10,ZNF496,RNF165,ZBTB49,PADI2,ZHX1,ATXN2L,HMGCR,CPT1C,DHX35,IGF1,ZIC5,KIAA1755,SCIN,ITPKA,KCND2,STMN1,LMO2,PACRG,ZNF667-AS1,MAP2,MAP4,MARK1,SAMD5,MSI1,MSR1,NCAM2,NF1,SMIM11A,NUCB2,OPA1,ZNF713,GPR137C,CNTN3,PAX6,DPY19L2P2,ETFRF1,PCDH9,PDE4D,PFKFB3,TMEM38A,KCTD15,GPSM2,MTRF1L,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R2C,PRKACB,SLC26A11,RELN,CNNM2,BCAS3,GDPD2,SNRK,PIGG,MTMR10,ZSCAN2,FAM66C,SH3TC2,RASGRF2,MSANTD2,ERI2,FIGN,RGS12,TMLHE,EXD2,ALG9,CARF,ROBO2,SNX22,ARMH4,BAALC,SGSM1,FAM192A,SAFB,MRAS,HSPA4L,ZFP30,FRMPD1,ARX,FERMT1,MYO18A,SHC4,FBXO11,FHOD3,NLGN1,DZIP1,PPP4R3A,SLC6A8,SLC8A1,CCDC88A,TTC17,KIF13A,TMCC1,KDM4B,DOP1A,TRERF1,NMNAT2,MCF2L2,RBM26,ATP10B,SEPT3,SYT1,COBL,ZFP90,FAM189A1,SIK3,TEK,PMS2CL,C18orf54,TIAM1,R3HDM1,KAT6B,PIK3R5,TPM1,TPM2,ZKSCAN5,UBE3A,LINC00689,UGT8,USP1,BCL2L13,GUSBP1,LGI4,ZNF28,ZNF540,ZNF138,CELF4,AMZ1,TFIP11,ZFAND5,NT5M,DNALI1,STOX2,FAM47E,DOCK8,UBE3B,FAM219B,JMJD1C,TRAM2-AS1,RNF170,NETO2,JPH3" MicroRNA hsa-miR-4295:mirSVR_highEffct hsa-miR-4295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-98 4.20E-94 1.14E-96 1.05E-95 227 1164 "CLK4,NCKAP5,ADCY6,CCDC85A,GALNT13,AXIN2,PLEKHH1,KIAA1211,BEND6,HECW2,OSBPL1A,WDR35,HFM1,ALCAM,SRPX,ABCD2,FAM135A,LRCH2,LCORL,APAF1,APC,LINC00173,STK33,NCOA1,STX16,ZNF583,ADAM23,TTLL9,ADGRB3,NRP2,DST,C5,THSD7A,KALRN,CAST,RUNX1T1,USP6,TIGD7,CFL2,CHN2,PLAA,CLTC,AKAP7,ARMC8,FAM149A,CLOCK,CREM,GDA,CSF1,LRIG1,SIPA1L1,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,GREB1,ARHGEF4,PPP6R2,CCDC144A,CYBB,BOC,DCAF8,ZFYVE16,LONRF1,SPATA2,FBXL5,KIAA0319,RHOBTB1,SPOCK3,WDR20,DPYSL2,ABCC5,GOLT1B,AASDH,WDPCP,EDN1,FAM13A,KMT5B,EGR3,CERCAM,PAN3,ENPP6,SRRM1,RASL12,ACSL4,GORAB,MED12L,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,NBEA,TPK1,B4GALNT1,ERAP1,ARFIP1,SESN1,ADAM28,RAB30,TNRC6A,MSL3,KDM2B,MAP7D2,RAB40B,PRUNE2,GRB10,CIT,RNF165,BACH2,IRF8,ZIC5,LRRCC1,ZNF678,KCNN3,CREG2,LIG4,NCOA7,MAP4,MATN3,MBNL1,LRP1B,LYRM9,ZNF862,MYT1,NELL2,CNOT4,NTRK2,OCRL,LOC100128398,PCSK5,PDE1C,CCSER2,JAKMIP1,PURG,LRP12,SCHIP1,GRAMD1C,PSD,MTMR10,PTPRG,PID1,CEP97,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,RET,ERI2,SLC25A36,KLHDC8A,CARF,ROBO2,EPHA10,ATP8B4,LRRK2,CLIP1,RTN1,LRFN5,TNFRSF19,PEAR1,ARX,KIF16B,CHD9,SYBU,SEC31A,BTBD3,WDR47,SEPHS1,SLC8A1,CCDC88A,BTBD7,SNAP25,KIF13A,USP33,TRERF1,DOK5,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,NKAIN2,ERBIN,MPRIP,NUDT10,PLCB1,SYN2,ANKRD12,MTCL1,CAMTA1,FBXW11,ZEB1,PCDHB4,TEK,DICER1,ZFPM2,ITGB3BP,SLC44A1,ERCC6L2,R3HDM1,CSMD1,TNS1,TSC1,UBC,FAM155A,CCDC14,WRN,ZNF711,ZNF74,SPHK2,ZBTB38,REEP1,FSTL5,MAP3K12,MFF,STOX2,WNK3,PLSCR4,RGS7BP,UBE3B,NHSL1,FXR1,FRMD6" MicroRNA hsa-miR-519b-3p:mirSVR_lowEffct hsa-miR-519b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.93E-98 5.55E-94 1.50E-96 1.38E-95 275 1714 "SYS1,GALNT16,CCDC85A,ADD1,USP31,RNF150,ADRA1B,BEND6,HECW2,KIAA1324,WDR35,OSBPL8,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,TNRC6C,CDK10,PLA2G4C,MARCH3,NCOA1,NUMB,INSYN2B,DPY19L3,ADGRB3,RGS11,BCL7A,FUBP1,MTMR2,SGCE,KALRN,CAMK2G,CBR1,CBFA2T2,C1orf52,NOG,MS4A7,B4GALT6,EPS15L1,CLTC,QKI,CNR1,IQCK,PCYT1B,ZFP28,CNRIP1,AKAP12,HAPLN1,TRIM69,PDE4DIP,CNTNAP2,FAM169A,APPL1,DCAF4,RUBCN,GAPVD1,ZNF337,DGKB,DGKG,DNAL1,SPATA2,MFAP3L,ZC3H11A,GUCD1,RHOBTB1,SNAP91,HS3ST2,CPEB2,DMTF1,SLC25A18,ACOT8,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,PAN3,EMX2,ERBB4,MRPL37,TLR7,KATNAL1,ST3GAL6,MED12L,POLK,SEC23B,PCYOX1,ATP13A4,ANKFY1,NOP56,NELFCD,CELF1,GAD1,ZNF274,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,DBF4,TNRC6A,MSL3,CBX1,GPT2,ADGRA3,GPD2,GPR34,PCLO,ZNF496,BTN2A1,SOX21,GUCY1A1,IRAK3,HNF4G,DHX35,SHISA6,CELF5,IGF1,INPP5B,SLC35G1,KIT,LAMP2,CAMK2N2,SFXN5,LMO2,ZNF667-AS1,MAP2,MAP6,MAPT,SCAMP5,AFF1,PTOV1,NRBP2,TAGLN3,LYRM9,MYO5A,MYO9A,P2RY13,NBL1,NCF2,SFR1,NFIX,NPTX2,NUCB2,OPRL1,PAX6,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,DUSP26,XRN1,GPSM2,SLC25A23,LRP12,SDK2,ING3,MINDY2,CCDC144B,MAPK3,MAPK4,DEF8,MTMR10,PTPRD,PTPRE,FAM184A,RBBP8,RADX,REV3L,GTDC1,PRIMA1,LGI2,ROBO2,ELP2,NEK11,FBXW7,ZC3H14,GLDN,RPS20,CLIP1,ZNF331,SATB1,SCN2B,TNFRSF19,PEAR1,PUF60,FBXO11,NUBPL,WDR37,BTBD3,WDR47,SLC6A8,KDM4D,SLC8A1,SLC11A1,SLC12A2,NAPB,TET1,CPEB4,ZNF667,TTC17,SNAP25,SNCA,MBD5,PDZD2,FNBP1,SP4,UHRF1BP1L,KDM4C,ZBTB43,TSPYL2,RBM26,NFASC,SEPT8,DIP2A,NSFL1C,SYN2,TACC1,MTCL1,EXOC7,ATMIN,TCF4,CUX2,ZEB1,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,ITGB3BP,AP4E1,TIAM1,RIMBP2,RGMB,SMUG1,TRPS1,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,CLDND1,MICU3,KCNT2,LYPD6,ZBTB38,EMSY,SLC38A1,EVI5,STOX2,PRDM8,SLC17A7,FAM13C,FZD3,ST7,UBE3B,FBXO36,FAM219B,NLRP3,TTC7A,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-miR-3159:mirSVR_lowEffct hsa-miR-3159:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-97 6.46E-94 1.74E-96 1.60E-95 252 1443 "CLK4,NCKAP5,TMEM132B,CCDC85A,TMCC3,ADD2,MTUS1,PCDH19,OSBPL1A,CC2D2A,AK2,TAOK1,CEP126,CARNS1,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,APOC1,TNRC6C,CDK10,TMEFF1,ARNTL,CDK13,N4BP2L1,NRP2,SYNJ2,RAB29,CACNA2D1,CABP7,CALM1,PRC1,CBR1,KRIT1,SCARB1,DGKI,LOC730101,LARGE1,CCPG1,CHN1,LHX2,CLTC,FAM19A5,HECTD1,CNN3,AKAP7,COL4A5,AKAP5,AHCTF1,C2CD2,AKAP12,GDA,SNCAIP,ARHGEF10,CSNK1G3,FAM169A,CTH,ARHGEF4,RIMS2,KIAA0408,MAML1,DNAL1,ARMCX4,RAB39B,DYNC1I1,NR1D2,CDON,PDCD6IP,ECM2,MAMLD1,DNAJB6,EDN1,EDNRA,KLHL5,RGS17,TMEM35A,EPB41L2,COQ7,DNAJC27,GMPR2,FAM198B,SH3YL1,DLC1,FCGR3A,FKTN,FGF13,SYNCRIP,FLT1,ANKFY1,PDLIM5,FAM49B,ZNF605,FYN,HRASLS5,GABRG1,DENND2A,GAD1,C15orf41,IGSF5,SESN1,TNRC6A,CBX1,LUZP2,GNAO1,ADGRA3,GPD1,FUT10,GPR34,PCLO,GRIK4,PRDM5,RASSF8,MAN1B1,ELOVL5,GABARAPL2,HNMT,AGFG1,SMAP1,C2orf72,SOWAHA,RBPJ,LRRCC1,NME9,KCND1,KCNK3,CYP27C1,LAMP2,HECTD2,MAN2A2,MAT2A,MBNL1,TM6SF1,MIA2,MID1,MMP16,ZNF92,LAYN,MYO7A,NFE2L2,ALDH1L2,NTRK2,GPR137C,CNTN3,PAX6,PDE4A,PDE4D,NALCN,ZNF655,CCSER2,ZFYVE21,RETREG1,PPARA,PPM1B,RANBP3L,RASGEF1B,EPDR1,HYDIN,DIRAS2,SAMD9,PIGG,PTCH1,PTN,ZNF615,USP47,RAD51D,SH3TC2,NWD1,RAP1GDS1,OXR1,RASGRF1,RASGRF2,ZDHHC14,MSANTD2,REV3L,ERI2,GTDC1,PBRM1,RNASEL,PCMTD2,NEK11,MCMBP,PTGR2,HUNK,ZNF331,ATXN7,SCN7A,GALNT10,MRAS,FERMT1,FBXO11,ST6GAL1,CNKSR2,DZIP1,ABLIM3,ARHGEF40,TET1,CPEB4,INTS9,LIMCH1,MBD5,CABCOCO1,PDZD2,TRERF1,SOX11,GLT8D1,HECW1,KDM4C,CDK19,POGZ,SST,SSTR1,SS18,RGL1,SULF2,SEPT3,STXBP1,JMJD6,C12orf76,TACC1,CAMTA1,EXOC7,PDLIM2,ALG1,AGTPBP1,KLHL4,TPCN2,TRIM2,DOCK9,OBSL1,C18orf54,ASXL3,ERCC6L2,KAT6B,CDK20,C9orf85,PDSS1,XRCC4,ZIC1,ZNF711,ZNF24,LYPD6,ZNF189,SIGLEC10,NAV3,EPM2A,FZD3,ADAMTSL3,MSRB3,NETO2,SOCS4,LAS1L,PRRT4" MicroRNA hsa-miR-1228:mirSVR_lowEffct hsa-miR-1228:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-97 6.82E-94 1.83E-96 1.68E-95 267 1619 "RALGAPA1,KLHL32,RNF150,ZNF608,NME5,SMIM17,AMPH,FGD2,MAP4K3,FAM131A,TMEFF1,SPTBN4,ZFYVE28,ARRB1,LINC00173,CDK13,STK33,CHID1,EIF4G3,SLC2A11,N4BP2L1,RIPK1,ADAM15,ADGRB2,BMPR1B,SYNJ2,CA8,CAST,RUNX1T1,PRC1,ZNF501,CLDN10,USP6,CBFA2T2,C1orf52,ZMYM4,TIGD7,SRSF11,EPS15L1,CPNE6,PPT2,STOML1,CLTB,CLTC,ABCG2,SULT4A1,MAP4K4,CNR1,AKAP7,COL4A5,LETMD1,CLOCK,RBM39,CRY2,ANKRD44,CSF1,VAC14-AS1,PLXNA4,SLITRK5,PPP6R2,DCAF4,RUBCN,MYADM,ZNF337,LONRF1,KIAA0586,ARMCX4,MYEF2,GUCD1,POM121,SV2B,GRIN3A,RAB39B,RPS6KL1,DPP6,ACOT8,DTNA,MAMLD1,DNM1L,E2F5,FAM13A,APH1A,MRO,EIF4G2,MTSS1L,STX2,VPS26C,MRVI1,CHST15,FDFT1,OLFM1,POLR1B,POLK,C2orf88,WDR83,TMEM107,SMC2,ZNF605,CGREF1,MPP6,ABLIM2,NEURL4,GABBR1,GALC,ZNF234,TMEM8B,KIAA1841,TUBGCP4,SULT1C4,USP19,MALT1,RUNDC3A,ZNF276,COPS8,TNRC6A,MSL3,ADGRA3,PRUNE2,GRB10,GRIA2,GRM2,FAM107A,RNFT2,ZNF491,DHX35,SMAP1,MSL1,ZNF546,ZIC5,TJAP1,IL6R,ITGA7,LINC00634,LAMP2,NCOA7,ZFYVE27,MAP2,SHC3,MEIS1,MEIS2,MID1,MN1,MYO6,MYO7A,RTL5,ZC3H12B,VWA2,NRCAM,IGSF11,P2RX7,PCDHGC3,PDCD2,NALCN,NLE1,ZNF426,PURG,PPARA,TATDN3,PPP2R5E,CEP41,MAPK10,MASP1,BCAS3,CNTLN,PTK2,PTPRB,PTPRD,PTPRG,ACSM5,OXR1,ZDHHC14,PRRT2,RFX3,UBR7,KCTD17,RNH1,CCDC102B,SNX22,MCMBP,SGSM1,TCP11L1,PTGR2,RPS20,ZNF568,ZNF331,DGLUCY,SEMA6D,SATB1,PEAR1,ASAP3,CHD9,DZIP1,NUBPL,DHX30,KANSL3,PKNOX2,SLC6A8,KBTBD4,ELMO2,DMRTC1,CDK5RAP2,LIMCH1,SNCA,CMTR2,SNRPN,FAM219A,SOX3,IZUMO4,SPP1,ERC1,ZC3H13,NFASC,CAMTA2,POGZ,SSTR1,LARP4,MPRIP,KANK1,SULF2,ZC3H4,SYNE2,VPS13A,DNAJC9,SYPL1,SYT1,C12orf76,FBXW11,KLHL4,DMXL2,ZEB1,TPCN2,TCF12,USP32P1,CYB561A3,FAM200B,SIRT1,ZFPM2,ARL10,TIAM1,HEY1,KAT6B,C9orf85,SMUG1,STXBP4,DCBLD1,CLHC1,CLEC2L,LINC00689,LAT2,RICTOR,ELFN1,ZBTB38,POLR3H,ANKS1B,PCBP1-AS1,MEIS3,UPF3A,DHX33,LINC02210,PRDM10,HPS4,FAM47E,RGS7BP,MSRB3,IFT88,LAS1L,FAM198A" MicroRNA hsa-miR-4289:mirSVR_lowEffct hsa-miR-4289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.28E-97 7.17E-94 1.92E-96 1.77E-95 276 1728 "RALGAPA1,ASPHD1,KDM5D,BRAP,BEND6,SLC24A4,NME5,OSBPL6,SPARCL1,BBOX1,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,MAGEE2,UPRT,BCAS1,RASL11B,EIF4G3,ATP2B2,N4BP2L1,ADAM15,BCHE,BID,BMP7,FUBP1,CACNA1B,DDR1,CACNB4,THSD7A,CALM1,PTBP2,CAMK2G,SLC25A14,CAST,SPAG9,NFS1,CBR1,LRBA,DLGAP1,COPB2,CHGB,CHN2,QKI,CNTN1,AKAP7,ARMC8,FAM149A,SEC31B,SNCAIP,OSBPL3,CSNK1G3,PLXNA4,CYBB,ARHGAP32,ZNF337,KCTD8,TMEM170A,PABPC5,JAKMIP2,ZBTB24,MFAP3L,FBXL5,KIAA0319,PLPPR4,SNAP91,EXOG,RAB39B,DMTF1,DPP6,ARRDC4,ECM2,MAMLD1,DNAJB6,GOLT1B,E2F5,EBF1,EDNRB,SEMA3D,KLHL5,PHF20L1,KMT5B,EIF4G2,RGS17,DCTN4,NCALD,EYA1,MRVI1,F5,ARMCX1,CLVS1,FCGR1A,CHST15,FGF1,POLR1B,FGF12,SUCO,UBE2E3,MEX3B,FOXF2,FLT1,ANKFY1,C2orf88,EFCAB2,POMT1,TMEM107,MPP6,HRASLS5,CHL1,IQGAP2,DISC1,CPLX2,SULT1C4,MSTN,ARFIP1,PPARGC1A,DBF4,HTATSF1,GPD2,PRUNE2,LPAR4,GRM8,MAP4K5,IRAK3,NXPH3,NCKAP1L,HLF,ELOVL5,AGBL5,HSF2,CELF5,IGF1,IL6ST,FAM69A,NME9,CREG2,STMN1,PAXBP1,LSS,SMAD9,CLEC18A,LYPLAL1,MAT2A,ADAM11,LRP1B,MEF2C,MEIS1,AFF1,MMP16,GIT1,MSR1,LAYN,NF1,ALDH1L2,NOVA1,DNHD1,PCBP3,NTRK3,NUCB2,OPA1,PCDH8,PCSK1,PDE4D,PIK3R1,FAM216A,MTRF1L,LRP12,SCHIP1,MBOAT7,DRAM2,MINDY2,PPP2R5E,PPP3CA,EPDR1,MAPK9,MAPK10,FITM2,VPS13C,APTX,CNTLN,PTN,TMEM260,ZSCAN32,PTPRD,ZNF844,RAD17,ZNF793,SH3TC2,ENOX1,KHDRBS2,RDX,RET,REV3L,PRRT2,RGS3,SLC25A36,ROBO1,CCDC25,RPS6KA2,RYR3,ZNF331,CCDC112,AP1AR,SAFB,SATB1,TNFRSF19,MRAS,CHD9,SYBU,SEC31A,CCDC88A,SLC12A2,MAPKBP1,CMTR2,SNRPN,MYO16,SP4,HECW1,KDM4C,TEX2,TSPYL2,RBM26,LMO3,POGZ,SSTR2,ELOVL4,CEP68,TTBK2,RGL1,DIP2A,NSFL1C,KLHL7,NECAB1,ZC3H4,SYNE2,ARHGEF9,PJA1,EXOC7,TBCEL,KLHL4,ZFP90,ZEB1,TCF12,SYNE1,SLC19A3,RNF175,CYB561A3,SIRT1,ZFPM2,C18orf54,ITGB3BP,AKTIP,R3HDM1,TP53BP2,C9orf85,TRO,DCBLD1,FAM155A,UBE2H,UGT8,P2RY12,WRN,RICTOR,XRCC4,KCNT2,MKRN3,LYPD6,FSTL5,EML6,ANKS1B,ZFAND5,SMARCAD1,MDH1B,FZD3,HNRNPA3,FBXO36,NETO1" MicroRNA hsa-miR-515-5p:mirSVR_highEffct hsa-miR-515-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-97 7.93E-94 2.12E-96 1.95E-95 270 1656 "ABCF1,SYN3,ABHD6,NCKAP5,ADCY6,PLEKHH1,PWWP2A,ADRA1D,BEND6,DPY19L2P4,SPOP,SRPX,CEP126,SUGT1P4-STRA6LP-CCDC180,APAF1,UPRT,PPP4R4,ZFYVE28,CDK13,ZBTB10,CHRD,NCOA1,SLC4A4,ATP1B3,ALDH7A1,DPY19L3,ADAM15,NRP2,ZNF599,CFLAR,BMPR1B,SYNJ1,ARHGEF7,CACNA1A,CALB2,CALM1,PTBP2,CAST,HIP1R,SPAG9,CD38,L3MBTL4,CDO1,CLGN,B4GALT6,ABCG2,QKI,MAP4K4,AKAP6,SLC4A8,NCOR1,CS,SNCAIP,VAC14-AS1,PDE4DIP,PLXNA4,DZIP3,UBXN2A,PUM1,RIMS2,USP6NL,CCDC144A,DOCK4,GPRASP1,ARHGAP24,MATR3,PABPC5,ARMCX4,C2CD2L,DDX46,RHOBTB1,SNAP91,SACS,CHRDL1,DMD,USP3,CPEB2,DMTF1,GOLT1B,EDN1,EDN3,HIPK3,SEMA3D,YAF2,FAM13A,KMT5B,GOLGA7,ASB3,EIF4G2,COPS4,TENM1,RGS17,PAN3,LRRC17,RASGRP2,ENPP6,DENND4A,ETV1,EXTL2,ADGRV1,CLVS1,ACSL4,TAOK3,RACK1,CEP78,GORAB,SEC24B,FER,FGF12,IP6K2,PCYOX1,SYNCRIP,RGPD5,FOXO3,SEMA4D,ATP13A4,TMEM107,SPECC1,PDLIM5,ATP2C1,ZNF605,MSANTD4,OGA,SDCBP2,MEGF11,HRASLS5,GABRB3,DISC1,ACSS1,TUBGCP4,SULT1C4,MSTN,GHR,PPARGC1A,COPS8,HPGDS,DBF4,TNRC6A,ZNF638,CBX1,MAP7D2,LUZP2,GPD2,TDRKH,GRIA2,AP4S1,HAS2,MIER3,HNF4G,SMAP1,MSL1,LRRCC1,FAM69A,KCND1,KCND2,KCNJ5,KCNN1,KIF2A,CYP27C1,CAMK2N2,HECTD2,MBD1,KCTD6,MITF,MN1,ZNF680,ADAM22,ZNF92,NACA,BEX5,NCAM2,NF1,DNHD1,NPTX1,SETD4,OPA1,CLDN11,PRTG,NALCN,SEMA5B,PIK3R1,ZNF655,ZFYVE21,XRN1,MAPKAP1,FSD1,PPARA,EPDR1,GRAMD1C,CNNM2,GDPD2,MTMR10,PTN,TMEM260,PTPRD,PTPRG,PEX2,CEP97,ZNF793,SUSD4,ZNF493,RBBP6,RDX,RGS12,EXD2,ALG9,CARF,GSTCD,RPE,NEK11,SPIN3,ATP8B4,TCP11L1,ABCA11P,KCNIP1,NCBP3,AP1AR,SCN8A,FNIP1,CASC3,FAM102A,HKDC1,FBXO11,WDR37,EPN2,ARHGEF40,SIRT2,RCOR3,MBD5,ZNF415,TMCC1,FAM126B,BDP1,RBM26,SPART,POGZ,NKAIN2,DIP2A,VPS13A,TPCN2,TRIM2,TCF12,SYNE1,PCDHB6,FRYL,C18orf54,ITGB3BP,AP4E1,TPM1,NPL,RGMB,TSC1,PRR18,VSNL1,ZNF708,ZNF19,ZNF154,ZNF177,INTS3,ZXDA,CADM2,ADAMTS9,CIAPIN1,NAV3,KCNAB1,PDSS2,RGS7BP,DNAH10,NETO1,DPF3" MicroRNA hsa-miR-497:mirSVR_highEffct hsa-miR-497:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-97 8.33E-94 2.22E-96 2.04E-95 245 1365 "ABCF1,KCNH8,NCKAP5,SYS1,CCDC85A,GALNT13,ADD2,AXIN2,ADRB2,OLMALINC,AP2A1,SMIM17,SRPX,CEP126,ARHGAP20,FAM135A,OGT,ANK2,MAGEE2,BCAS1,PPFIA3,LGR5,CDC14B,CASK,STK33,ZBTB10,TTLL9,MPDZ,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,CA8,CACNA1B,KALRN,RUNX1T1,ARHGEF1,TIGD7,PPT2,CLCN3,QKI,SLC4A8,TBPL1,BAG4,MYRIP,SEC31B,PREPL,CRYM,LRIG1,SOCS5,ERC2,ZSCAN23,USP6NL,ARHGAP32,KATNAL2,RIPOR2,DCAF8,KCTD8,ARMCX2,YTHDC1,JAKMIP2,SPOCK3,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SEMA3D,PHF20L1,MBNL2,PLEKHA1,PAN3,RCAN2,GPHN,DENND4A,CEP85L,SPEG,EYA1,NRN1,ACSL4,RACK1,FGFR1,SUCO,RGPD5,SLC37A3,PDLIM5,CELF1,CSPG5,NSG1,DISC1,SESN1,USP19,PCDH17,GHR,FERMT2,GPD2,GRIA2,RNF165,RASSF8,ZHX1,FRMD3,MSL1,RBPJ,NIM1K,SCIN,INPP1,NME9,SLC35G1,KCND2,KIF2A,KIF5A,LAMP2,SYTL4,NCOA7,ZFYVE27,MAP4,LYPLAL1,MARK3,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,THYN1,RTL5,NDP,SLC11A2,GPR137C,CNTN3,ETFRF1,PCDH9,PDE3A,PDE4D,SLC10A4,PIK3R1,JAKMIP1,PURG,PSAT1,MAGEL2,RETREG2,EPB41L4B,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,CNTLN,STK32A,ZSCAN32,PTPRD,NKAIN1,PID1,TMEM255A,FAT4,RBBP6,ZDHHC14,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,ARMH4,FBXW7,ABCA11P,ATAT1,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN8A,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,ANKRD6,FAM81A,PREX2,ARHGEF40,CCDC88A,KBTBD4,SLC22A4,RCOR3,SNAP25,MBD5,SNRPN,UNC5B,ZC3H13,TSPYL2,NFASC,SSTR1,NKAIN2,PHLDB1,PRRC2C,SYNE2,SYPL1,C12orf76,TBCEL,SATB2,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ERCC6L2,KAT6B,TPM2,RUNDC3B,LGI4,TRIM9,EML6,ANKS1B,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-3184:mirSVR_lowEffct hsa-miR-3184:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-97 9.29E-94 2.46E-96 2.27E-95 289 1891 "ACHE,AS3MT,ACTN1,ADCY6,ADD2,OLMALINC,KIAA1324,AK2,C1QTNF1,CARNS1,SYT13,PITPNM2,AMPH,AMT,PI16,PHF12,KCNAB2,PHYHD1,TNRC6C,ARRB1,ARRB2,ASGR1,SLC4A4,ATP2B2,ADGRB2,RGS9,KSR1,SCAPER,GYG2,DDR1,HAP1,CAPN3,PRC1,CBLN1,CBFA2T2,SYNGR3,CDC25B,ZMYM4,LRRFIP1,CRLF1,NUMBL,CACNA2D2,CHN2,B4GALT6,TAOK2,NDST3,SRP14-AS1,ARHGEF6,CABP1,C2CD2,MROH8,SEC24C,SLITRK5,DZIP3,CTH,ARHGEF4,PUM1,RUBCN,HDAC9,CENPL,EARS2,TM9SF4,SPOCK2,DBN1,MYEF2,B3GAT3,KIAA0319,KLHL3,TMEM130,POM121,PARD6A,WDR20,DNAH9,DTNA,TOM1,ABCC5,SEZ6L2,ANKRD46,TMTC1,CELSR3,FAM13A,PHF20L1,EGR3,GOLGA7,ELN,SLC43A2,STX2,ERBB2,DENND4A,SPEG,MRPL37,REEP2,CORO2B,FCGRT,SPSB4,FGFR1,BAIAP2,TMEM164,SCARA3,HPCAL4,IP6K2,AGAP2,IQCG,SYT3,CINP,STAMBP,GABBR1,GABRA3,GHDC,IQGAP2,TMEM8B,DISC1,ALDH1L1,SRCAP,MSTN,AHDC1,GGT5,ZNF276,TXNL4A,TCERG1,GPT2,PRRC2B,LILRB4,PCLO,STMN2,ADAMTS13,GRIK5,GRM2,RABL2A,SOX21,RNFT2,ATOH8,UBE2QL1,HBA1,PADI2,ATXN2L,ARHGAP36,MYLK2,LRRC25,ITGA7,C2CD4C,GPR62,KCNJ5,KCNN1,KCNN2,KCNQ3,A1BG-AS1,STMN1,MARK1,ADAM11,SCAMP5,MOV10,GIT1,MSI1,BLOC1S2,PTOV1,NRBP2,MYO7A,NEXMIF,FXYD7,NBL1,NEFM,NEFH,NINJ2,DNHD1,NPTX2,PCBP3,NTRK3,P2RY1,PALM,PCDH8,SNX10,PKM,KCTD15,MTRF1L,SCHIP1,SEPT4,MBOAT7,POU6F1,NKAIN4,MAPK3,MAPK4,DIRAS2,MASP1,CNNM2,NDUFS7,WBP1L,GDPD2,PIGG,PTCH1,BDNF-AS,ELOVL2,CASTOR1,C1orf109,NKAIN1,RAD51D,IQSEC3,RAP1GDS1,RFX2,KCTD17,LGI2,TMLHE,ROBO1,EPHA10,SGSM1,STK32B,EMID1,ABCA11P,ATAT1,KCNIP3,CLIP1,DGLUCY,SATB1,SBF1,CASC3,MRAS,FAM102A,FUZ,SHMT2,DZIP1,PEX26,LIMS2,PKNOX2,ARHGEF40,LGI3,SMARCA4,SMARCC2,ANKRD36,MAPKBP1,KDM4B,FAM219A,ZSWIM8,NMNAT2,CDK19,TSPYL2,CAMTA2,MESP1,SSTR1,SSPO,SEPT8,SEPT3,NUDT10,SYN1,ARC,SYP,MLST8,EXOC7,TAL1,MGRN1,ATMIN,NSD1,ARHGAP9,RNF216P1,GALNT17,TK2,ICAM5,NR2E1,FAM124A,ANKRD24,RGMB,TRIO,TRO,STXBP4,TRPM2,SSBP2,GORASP1,PLEKHH2,PLPPR2,VGF,LMF1,TSPAN11,KLC2,ATP6V0E2,NDRG4,CELF4,ZNF154,MEIS3,INTS3,EMSY,NT5M,GDPD5,ADAMTS9,URM1,FIP1L1,DOCK8,JMJD1C,ADAMTS10,LAS1L,JPH3" MicroRNA hsa-miR-187*:mirSVR_lowEffct hsa-miR-187*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-97 1.02E-93 2.71E-96 2.50E-95 250 1423 "ACADM,ADD1,ESYT2,PTCHD1,LRFN2,OSBPL8,TXNDC16,SPARCL1,USP35,ALCAM,SRPX,UNC79,FAM135A,GPRASP2,ZNF687,CDC42BPA,SHROOM2,CASK,STK33,NCOA1,ATP1B3,DPY19L3,BCHE,ARHGEF7,JAZF1,CALM1,KALRN,PTBP2,CH25H,ISPD,SPAG9,TIGD7,CLGN,CHN2,PLEKHB1,CPNE6,RAB28,FAM19A5,QKI,CNTN1,SLC4A8,ZNF521,SEC31B,ANKRD44,ARHGEF10,SIPA1L1,APPL1,UBXN2A,GREB1,ARHGEF4,RIMS2,ARHGAP32,HDAC4,KIAA0586,DNAL1,DBN1,SPATA2,YTHDC1,ZBTB24,MYEF2,KIAA0319,ZC3H11A,DDX46,SNAP91,GRIN3A,RAB39B,DMD,CD99L2,CPEB2,DMTF1,ABCC5,DNM1L,RASGRP1,FRY,APH1A,TMEM132E,RASA4,GOLGA7,EIF4G2,CEP85L,ZNF549,EZH1,CLVS1,PCYOX1,FLT1,NOP56,TMEM107,SMC2,UFM1,STAMBP,CAMKK2,ATP6V1H,ZNF605,CGREF1,STAU2,GAD1,DISC1,SULT1C4,MSTN,GDF9,PPARGC1A,COPS8,SPIN1,TNRC6A,GLUL,LUZP2,FERMT2,GPR37,GRM2,FAM107A,PADI2,ELOVL5,HNF4G,ZDHHC15,NEGR1,AGFG1,SHISA6,LRRCC1,IL6R,SLC6A17,KCNK3,KIT,IPO5,STXBP5,STMN1,SYTL4,NCOA7,MBP,CHIC1,TM6SF1,KCTD6,MIA2,AFDN,GIT1,N6AMT1,MXI1,LYRM9,HNRNPM,ZC3H12B,NEK1,ALDH1L2,NOVA1,NPR2,OCRL,GLIPR1L2,PCSK1,PDE4A,PDE4D,GPR85,GNG2,PIK3R1,ZNF655,MAGEL2,EPB41L4B,MINDY2,PPM1B,MAPK9,HYDIN,PRPSAP2,PTCH1,ANKHD1,PTN,PTPRG,TMEM231,USP47,ACSS3,ZNF793,SH3TC2,FAT4,ENOX1,RBBP6,RADX,RDX,TRIM68,RET,REV3L,UBR7,ZFHX4,MRAP2,GLDN,RTN1,NCBP3,S100B,DGLUCY,SATB1,TNFRSF19,KIF16B,CPEB3,FNDC3A,ST6GAL1,SLC6A11,RADIL,CCDC88A,INAVA,KIF13A,PDZRN3,SOX11,NMNAT2,SPART,TROVE2,LARP4,SEPT8,SULF2,TACC1,TAL1,AGTPBP1,TBL1X,TRIM2,TCF12,FAM200B,SIRT1,ZFPM2,AKTIP,TIMP4,ERCC6L2,TP53BP1,TPM1,RGMB,NR2C2,STXBP4,ANKRD20A2,ZKSCAN5,HIRA,FLRT2,CLDND1,ZBTB14,ZNF17,KCNT2,ZNF74,NDRG4,CELF4,EML6,EMSY,MFF,EVI5,STOX2,TUBA1A,ADAMTS9,NAV3,EPM2A,ST7,KAT6A,JMJD1C,RSPRY1,MSRB3,NHSL1,KLHDC1,FRMD6,IFT88,NETO1" MicroRNA hsa-miR-183*:mirSVR_highEffct hsa-miR-183*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-97 1.05E-93 2.77E-96 2.55E-95 271 1670 "ADD1,RNF150,INTS2,OSBPL8,C1QTNF3,SPARCL1,ALCAM,PCDH10,FAM135A,AMPH,ZFAT,ANK2,MAP4K3,PHF12,BCAS1,CDK13,BACH1,DST,SYNJ1,CACNB4,CALB1,SPAG9,KRIT1,CCNH,USP6,SCARB1,DGKI,LRBA,SEPT7,LARGE1,CHN2,B4GALT6,CLCN3,ABCG2,QKI,CNR1,ARMC8,AKAP6,AKAP5,ABI3BP,COX4I1,AHCTF1,CLOCK,PREPL,ANKRD44,NCOR2,SNCAIP,LRRC3B,ARHGEF10,VCAN,PNPLA8,CTH,ZSCAN23,KATNAL2,RIPOR2,LIN54,MATR3,KCTD8,DAPK1,PABPC5,ZNF804A,KIAA0319,DDX46,SNAP91,SACS,SPOCK3,WDR20,DMD,USP3,CDON,DMTF1,DPP6,DPYSL2,PDCD6IP,GOLT1B,EDIL3,EDNRB,SEMA3D,FRY,FSD1L,OPTN,MBNL2,KMT5B,AASS,KCTD3,PAN3,EIF1,SRRM1,CLVS1,FKTN,ZSCAN30,GORAB,GTF2IRD2,POLR1B,FGFR1,POLK,UBE2E3,HPCAL4,JKAMP,TVP23A,ERAP1,GATM,SESN1,GHR,MALT1,RAB30,TNRC6A,ZNF638,LUZP2,ADGRA3,GPD2,PRUNE2,GPR37,PLCD4,LINGO1,GUCY1B1,FRMD3,BACH2,MIER3,HNF4G,C9orf129,MSL1,LRRCC1,IL6ST,ZNF678,SLC35G1,METTL21A,KIF5A,STXBP5,LAMA2,LIMS1,ASPRV1,MARK3,MAT2A,MATN3,MBNL1,MEIS1,MEIS2,SRSF12,MSR1,RTL5,MYT1,NF1,NFE2L2,NOVA1,DNHD1,IGSF11,CNTN3,PCSK1,CDK18,PDE4B,PFKFB4,ZNF655,FAM218A,FAM216A,PURG,ANKRD16,ING3,PPP3CC,GRAMD1C,VPS13C,SNRK,PTPRO,PID1,RAD17,ZNF493,OXR1,RASGRF2,RDX,SLC25A36,ZFHX4,LGI2,CCDC82,EXD2,CARF,GSTCD,CCDC102B,NEK11,SPIN3,ATP8B4,ABCA11P,KCNIP3,ZNF354C,SALL1,SATB1,LRFN5,SEC14L1,HSPA4L,FERMT1,KIF16B,CHD9,FNDC3A,FHOD3,R3HDM2,NLGN1,ANKRD6,FAM81A,KANSL3,ZNF430,SEPHS1,CCDC88A,SLC9A5,SLC12A2,SLC22A4,CPEB4,OGDHL,RCOR3,ANKRD36,ZNF415,SNRPN,GLT8D1,KDM4C,RBM26,PBLD,CLASP2,POGZ,ITPRID2,NKAIN2,NXT2,SEPT8,CEP68,ADHFE1,KLHL7,DNAJC9,PLCB1,SYPL1,COBL,MTCL1,PJA1,CAMTA1,ADGRL3,TBCEL,TCEA1,SATB2,ZFP90,RPGRIP1L,PCDHB7,PUM2,USP32P1,ZFPM2,AP4E1,AKTIP,SLC44A1,TMPO,NEIL2,PPIL6,TUBB1,UBE3A,ZNF781,CLDND1,RICTOR,ZNF711,ZNF708,ZNF28,KCNT2,ZNF138,FSTL5,ZNF189,FTSJ1,MAP3K12,CADM2,ADAMTS9,HPS4,PPP1R3F,WNK3,PLSCR4,PDSS2,CASC15,ADAMTSL3,SOCS4,ZNF30" MicroRNA hsa-miR-1261:mirSVR_lowEffct hsa-miR-1261:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-97 1.36E-93 3.58E-96 3.30E-95 245 1368 "RALGAPA1,ABCF1,FMNL2,GALNT13,PTCHD1,ADRA1D,BEND6,TBC1D14,TAOK1,SMIM17,SPOP,ALCAM,ABCD2,DPP10,PHF12,APBB2,TNRC6C,ARNTL,ATP2B2,SEC11C,NRP2,CFLAR,SYNJ2,SCAPER,MTMR2,CA8,THSD7A,RUNX1T1,METTL6,MTMR7,ARHGEF1,LOC730101,ABCG2,SRP14-AS1,MAP4K4,CNN3,IQCK,COL4A5,COX4I1,TOGARAM2,C2CD2,ENTPD4,CS,SEC24C,CSNK1E,SOCS5,VAC14-AS1,PHACTR3,KIAA0040,CTH,RUBCN,CYBB,KIAA0408,HDAC9,HDAC4,EARS2,DBI,GIT2,HEPH,TIAM2,LYPD1,RHOBTB1,RAB39B,NR1D2,DOCK2,DMTF1,DPP6,DRP2,ARRDC4,E2F5,EBF1,EDIL3,EDNRA,RASGRP1,FAM13A,PHF20L1,MRO,EGR3,ELN,ERBB4,DENND4A,ETV1,TUBA1B,FCGR3A,FER,MED12L,OLFM1,FGF13,FGF14,FGFR1,SUCO,PCYOX1,SYNCRIP,FOXO3,FLT1,ANKFY1,NELFCD,TPK1,AP4B1,GABBR1,HRASLS5,CHL1,DISC1,KIAA1841,NEU3,ALDH1L1,SPIN1,TDRKH,GPR12,STON1,LPAR4,BTN2A1,GSN,RNF165,GSTM5,BVES,FAM107A,MAP4K5,MUM1,RASSF8,HLF,HMGCL,HNF4G,ZNF491,ZDHHC15,IRF8,IGF1,LRRCC1,KCNH2,CYP27C1,STMN1,PAXBP1,MAN2A2,LYPLAL1,MBNL1,CHIC1,LRP1B,SHC3,MEF2C,MITF,P2RY13,ZC3H12B,NEK1,DNHD1,NTRK3,IGSF11,ZNF713,PCDH9,GPR85,PFKFB2,CCSER2,RETREG1,SLC25A23,PURG,LRP12,SH3KBP1,PPARA,PPM1B,CCDC144B,PPP2R2C,PPP2R5E,PKIA,MTMR10,SPDL1,PTPN13,PTPRB,C1orf109,TUG1,PID1,CEP97,TMEM255A,RAP1GDS1,ZNF493,RASGRF2,RBBP6,GTDC1,FIGN,RIC8B,SETD5,ROBO2,CCDC25,YY1AP1,ATP8B4,RPS6KA2,MAP6D1,ZNF568,S100B,SALL1,ATXN2,SCP2,TNFRSF19,MRAS,COPZ1,KIF21A,FERMT1,FBXO11,FHOD3,DHX30,FAM214B,SLC6A11,GKAP1,ANKRD36,LIMCH1,SNCA,MBD5,SNRPN,MYO16,USP33,DOP1A,TRERF1,SP2,HECW1,KANK1,ARHGEF9,VPS13A,KIAA1107,DMXL2,RPGRIP1L,TNS2,SIK3,DICER1-AS1,TIAM1,ERCC6L2,NPL,RGMB,ELP5,TRPS1,CCDC14,RICTOR,XPO1,ZIC1,MKRN3,LYPD6,POLR3H,AMZ1,PRDM8,RNF103,CIAPIN1,GAL3ST3,KCNAB1,FIP1L1,WNK3,WNK2,FAM13C,CPNE4" MicroRNA hsa-miR-3116:mirSVR_lowEffct hsa-miR-3116:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-97 1.44E-93 3.79E-96 3.49E-95 276 1733 "DGCR6,SYN3,ACADM,KLHL32,ADD1,DPY19L2P4,AP2A2,CASKIN1,PCDH19,RTL9,C1QTNF1,CARNS1,PCDH10,FAM135A,OGT,PI16,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,EPB41L5,APLP1,NT5C3B,VAT1L,PPFIA3,LGR5,SHROOM2,SEMA4G,MADD,CASK,MARK4,NUMB,N4BP2L1,RIPK1,LINC00847,BCHE,DNAJC27-AS1,SYNJ2,SCAPER,CACNA1G,MYRF,BAIAP3,IL33,CA4,CA8,DDR1,CALB1,HAP1,CAPN3,RUNX1T1,KYAT1,SYNGR3,LRRFIP1,DLGAP1,CCPG1,SRSF11,CHN2,ARHGAP22,PLAA,QKI,COX4I1,SMARCAL1,ZFP28,SLC35F1,CPS1,CDC42BPB,CRYBB1,ABCG1,SNCAIP,OSBPL3,CSNK1G3,VAC14-AS1,PDE4DIP,FAM131B,CYBB,ARHGAP32,GAPVD1,SNPH,IST1,DAPK3,KIAA0753,TMCC2,CHRDL1,DMD,RPS6KL1,WDPCP,EDN1,PHC2,TMTC1,YAF2,EGFR,EGR3,TMEM35A,ENO2,GPHN,RASL12,SIRPB1,MRVI1,PTK2B,CHST15,FDFT1,PPP1R1B,SCARA3,HPCAL4,RGPD5,EVL,POMT1,CAMKK2,KHDRBS3,CELF1,TVP23A,SDCBP2,MEGF10,GABRA3,ZNF44,B4GALNT1,ZNF274,MTHFD2,DISC1,SEPT9,KIAA1841,NEU3,CYP46A1,GGT5,CRCP,MSL3,STARD3,ZNF638,GPT2,GP1BB,TDRKH,STON1,GRIK5,GRM2,ZNF496,BTN2A1,AP4S1,RNFT2,GUCY1A1,PADI2,BACH2,AGBL5,SHISA6,CELF5,ICA1,RBPJ,ITGAM,GATD1,A1BG-AS1,PAXBP1,SYTL4,NCOA7,LSS,MAN2A2,ZFYVE27,MAT2A,ADAM11,SCAMP5,AFDN,XRRA1,MSI1,BLOC1S2,ADAM22,PTOV1,LYRM9,MYO7A,FXYD7,NCF2,NFYA,NINJ2,NME4,NOVA1,PCBP3,NUCB2,PCSK5,PRTG,PDE4D,CCSER2,XRN1,PKM,SMOX,SLC25A23,PCDH18,LRP12,POLR2F,POU6F1,PPARA,CCDC144B,PRKAB2,HYDIN,MASP1,CNTLN,C1orf109,PEX2,TMEM231,SLC25A48,FAM66C,SUSD4,RASGRF1,TRIM68,PRRT2,DCUN1D2,C12orf49,EPHA10,MCMBP,MEG3,SATB1,SCN2B,PRCD,TNFRSF19,GALNT10,RASA3,MYO18A,FNDC3A,CNKSR2,WDR37,KANSL3,NAPB,LGI3,GKAP1,MAST1,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,PDZD2,ERC1,SPTAN1,ATP10B,SSTR1,ZC4H2,MPRIP,CEP68,PHLDB1,SYT1,MTCL1,TAL1,FAM208A,PDLIM2,TBCEL,SATB2,TPCN2,TRIM2,ARL10,ENHO,TLR4,ANKRD24,PRRT1,ZNF346,AMACR,FAM155A,MGAT5B,VAV1,VLDLR,WIPF1,ZIC1,LYPD6,AMZ1,TMEM198,ZNF213,DNALI1,SLC38A1,PRDM8,SEMA3B,URM1,EPM2A,FZD3,DOCK8,FAM219B,RSPRY1,TIGD6,RNF170,ADAMTS10,SOCS4,LAS1L" MicroRNA hsa-miR-154:mirSVR_lowEffct hsa-miR-154:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.59E-97 1.45E-93 3.79E-96 3.49E-95 247 1391 "ACADM,ACTN1,TMCC3,USP31,KIAA1211,ADRA1D,INTS2,OSBPL8,TXNDC16,CDC42BPA,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,BCAS1,IGDCC4,SLC2A11,BID,ZNF599,PROM1,FUBP1,CASTOR3,MTMR2,CACNB4,CABP7,KALRN,KYAT1,CCNH,C1orf52,ARHGEF2,NOG,SOCS6,C4orf33,QKI,TMEM184B,CNTN1,AKAP6,ZNF521,SLC35F1,FAM171B,RNF14,GDA,SNCAIP,RGS6,CSF2RA,CSNK1G3,VCAN,PLXNA4,SLITRK5,GREB1,RIMS2,CCDC144A,CENPL,MATR3,TMEM170A,DAPK1,DNAL1,ARMCX4,KIAA0753,FAM107B,DRP2,PDCD6IP,DNAJB6,TSPAN5,EDN1,EDNRB,PHC2,FCF1,PHF20L1,SUGP2,MRO,KMT5B,EPB41L2,RASGRP2,RRAGB,ABCA8,DLC1,ZSCAN30,ZNF589,OLFM1,MEX3B,RGPD5,SEMA4D,TMEM107,FAM49B,CAMKK2,ZNF605,KHDRBS3,CELF1,MSANTD4,ZMAT1,MEGF10,GABRG1,RAPGEF6,CYP46A1,PCDH17,MALT1,TNRC6A,MAP7D2,LUZP2,GPT2,GPD2,STON1,PCLO,SOX21,LINGO1,HAS2,FRMD3,NEGR1,ZNF546,C2orf72,LRRCC1,IL12A,IPO5,SYTL4,GPR155,MAP2,MARK1,MARK3,MATN3,MBP,CHIC1,LRP1B,PPM1L,MITF,MYO7A,RTL5,ZC3H12B,NCF2,IDNK,NEFH,NEK1,NF1,NME4,NOVA1,SLC11A2,SMIM11A,NTRK2,PCDH8,PDE4B,ZNF655,CCSER2,RETREG1,GPSM2,PURG,TRHDE,PPM1B,KANSL1,PRKACB,EPDR1,APTX,CNTLN,BDNF-AS,PTPN13,PTPRE,PEX2,ACSM5,PPP2R3C,CEP97,USP47,FAT4,FAM184A,RAP1GDS1,KHDRBS2,ERI2,ZDHHC4,SLC25A36,ZFHX4,LGI2,CCDC82,SUGCT,CARF,ROBO1,NEK11,FBXW7,HUNK,CLIP1,RTN1,AP1AR,SATB1,ATXN2,LRFN5,KIF27,PPM1E,KIF16B,CHD9,FBXO11,FNDC3A,BTBD3,KANSL3,BTBD7,ATF7IP,SMARCC2,ANKRD36,TMCC1,PDZD2,UNC5B,NFASC,SAMSN1,SS18,SEPT8,SEPT3,STXBP1,KLHL7,VPS13A,MTCL1,PJA1,ADGRL3,DOCK9,PCDHB9,GPRIN3,HIF3A,PMS2CL,SIRT1,ITGB3BP,AKTIP,ASXL3,ERCC6L2,TMPO,R3HDM1,PDSS1,NEIL2,TRO,STXBP4,SGK3,ZNF610,UGT8,BCL2L13,MGAT5B,RICTOR,ZIC1,ZNF24,TRIM9,ZFAND5,SMARCAD1,ZXDA,EMSY,DNALI1,EVI5,PLSCR4,UBE3B,KAT6A,HNRNPA3,FAM219B,SNX14,IFT88,RNF146,PRRT4" MicroRNA hsa-miR-548v:mirSVR_lowEffct hsa-miR-548v:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.30E-97 1.84E-93 4.81E-96 4.43E-95 259 1531 "ASIC1,NCKAP5,PSMG3-AS1,PWWP2A,KIAA1211,RNF150,ESYT2,LRFN2,BEND6,KLHL13,CC2D2A,SEMA6A,PCDH10,BBOX1,BEGAIN,AMPH,C6orf89,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,TMEFF1,ASPA,ATP1A1,ATP1B3,TTLL9,BCHE,SGCE,CAST,METTL6,ZBED1,CDH2,CDO1,CLGN,SRSF11,CHGB,NDST3,QKI,FHL5,ARMC8,AKAP6,SLC4A8,COX4I1,ZFP28,IGDCC3,ZNF385A,CPS1,SEC31B,CRHBP,HAPLN1,CRY2,RGS6,SOCS5,SLITRK5,UBXN2A,USP6NL,GPRASP1,RASSF2,TBC1D5,KIAA0586,MAML1,PABPC5,PITPNC1,SPATA2,KLHL3,ZC3H11A,DDX46,DYNC1I1,DMTF1,CASP8AP2,ABCC5,GOLT1B,EBF1,EDNRA,TMTC1,SUGP2,EGFR,KMT5B,EIF4G2,CALCRL,DENND4A,ABCA8,TMEM132C,SEC24B,GTF2IRD2,FGF14,SUCO,UBE2E3,MEX3B,PCYOX1,IQCG,FOXO3,ATP13A4,ANKFY1,JKAMP,TMEM107,KHDRBS3,CELF1,SARAF,TPPP3,HRASLS5,GABRG2,RAPGEF6,GATM,SULT1C4,GDF9,RNPS1,HPGDS,GNAL,LOXL3,GNAO1,FERMT2,GPD1,GPD2,STON1,MCHR1,GPR37,PCLO,PLCD4,CIT,LINC01089,PSIP1,RNFT2,PADI2,ZHX1,ELOVL5,AGBL5,LRRC75A,LRRCC1,KIAA1755,ZNF678,ITPKB,KTN1,PAXBP1,HECTD2,PIK3AP1,MAP6,MAT2A,MBNL1,MBP,KITLG,MITF,ADAM22,MYO9A,NEXMIF,ZC3H12B,CCDC13,NEK1,CNOT4,NPR2,NRCAM,NTRK2,IGSF11,OCRL,ZNF713,PCSK5,PDCD2,PDE3A,PDE4D,GNG2,PFKFB2,OLA1,CCSER2,XRN1,SMOX,PRIMPOL,SCHIP1,MAGEL2,ING3,POLR2F,PPARA,PPM1B,PPP2R2B,LRRN3,BCAS3,CNTLN,ANKHD1,PTK2,PTN,PTPN13,PTPRN,TMEM231,USP47,ACSS3,RAP1GDS1,RBBP6,KHDRBS2,RDX,ERI2,FIGN,MRPS18A,SETD5,C12orf49,KIRREL1,RORB,MRAP2,RPE,RPL15,ARMH4,MCMBP,SAFB,TNFRSF19,FOXRED1,FAM102A,SH3GL3,KIF16B,ASAP3,CPEB3,FNDC3A,BTBD3,SEPHS1,NAPB,LGI3,SNAP25,SNCA,MYO16,SOX3,BDP1,PEG10,SPART,LHPP,CLASP2,CLSTN2,NKAIN2,SEPT8,MTCL1,CAMTA1,AGTPBP1,TBCEL,TCF4,ZEB1,TPCN2,SLC19A3,CCDC173,ZFPM2,AKTIP,ERCC6L2,TP53BP2,RUSC1,RPRM,SLC35A4,GORASP1,KLC2,XPO1,ZNF24,ZNF70,NDRG4,ZBTB38,EML6,ZFAND5,EMSY,TUBA1A,FIP1L1,EPM2A,FAM13C,FZD3,GAN,FAM198A,SENP7" MicroRNA hsa-miR-4280:mirSVR_lowEffct hsa-miR-4280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-97 2.05E-93 5.34E-96 4.92E-95 243 1348 "FMNL2,KLHL32,GALNT13,BRAP,PLEKHH1,UNC5A,RTL9,HACE1,ABCD2,CARNS1,UNC79,AMPD2,AMPH,LRCH2,ANK2,APBB2,APC,PHYHD1,VAT1L,TNRC6C,USP37,SEMA4G,PRX,ZNF582,BID,CFLAR,PROM1,SCAPER,WASF1,IL33,DDR1,CALB1,KALRN,VXN,ISPD,MTMR7,CDH2,CCPG1,SRSF11,NDST3,CPNE6,CLTB,QKI,AKAP5,ZNF521,ZFP28,C2CD2,CREM,GDA,TRIM69,CSF1R,ARHGEF10,SUSD5,VCAN,PDE4DIP,PITPNM3,CTH,EARS2,DGKB,PABPC5,ARMCX4,ELMSAN1,ZBTB24,KIAA0319,RAB39B,CASP8AP2,SLC25A18,ARRDC4,ECM2,DNAJB6,EBF1,EDNRB,PHF20L1,KCTD3,EIF5,TNK2,RGS17,DCTN4,VPS13B,RCAN2,RABEPK,CEP85L,SPEG,ETV1,FAM198B,RPS6KC1,FCGRT,GORAB,FGFR1,FHL1,MEX3B,EFCAB2,JKAMP,CAMKK2,ATP6V1H,ATP2C1,ST6GALNAC3,NSG1,STAU2,MSANTD4,MPP6,MEGF11,CHL1,SIGLEC8,ZNF559,SULT1C4,MSTN,CYP46A1,GGT7,PPARGC1A,TCERG1,FERMT2,WDFY3-AS2,GPR12,GPR37,PCLO,DIDO1,KAT7,ADAMTS6,ZDHHC15,TCEAL6,IDH3A,C2orf72,ZNF678,SLC35G1,KCNQ3,KIF2A,KTN1,LAMP2,HECTD2,MBD1,MIA2,MITF,ZNF680,ADAM22,MSR1,ZNF92,RTL5,NELL2,NRCAM,NTRK2,IGSF11,DPY19L2P2,ETFRF1,PCSK1,PCSK5,PIK3C2A,ZFYVE21,PLCL1,PCDH18,PNMA3,ING3,SEPT4,EPB41L4B,PPARA,PPM1B,PRKAB2,PKIA,EPDR1,MAPK7,VPS13C,SNRK,WDR25,PTCH1,PTPRD,PTPRE,CASTOR1,NKAIN1,ZNF844,ZNF493,OXR1,RBBP6,RDX,REV3L,ERI2,ALG9,CCDC102B,SPIN3,ATP8B4,MEG3,ABCA11P,HSD11B1L,RYR3,TRAPPC13,AP1AR,SATB1,FNIP1,SUPT20H,PPM1E,CPEB3,FBXO11,FNDC3A,R3HDM2,CNKSR2,SEC31A,KANSL3,TET1,ZFP1,MBD5,SNRPN,USP33,DOP1A,PDZD2,SP4,NMNAT2,CLASP2,TROVE2,SS18,NECAB1,VPS13A,SYPL1,DMXL2,SATB2,TPCN2,DOCK9,USP32P1,ITGB3BP,AKTIP,ERCC6L2,WBP2,SYNPO2,TRO,STXBP4,OSBP2,USP1,P2RY12,ZNF708,MICU3,LYPD6,TCEAL7,ZNF138,ZBTB38,ZNF195,SLC38A1,ADAMTS9,SIGLEC10,KCNAB1,PARP11,PHTF2,RNF170,NETO2,NETO1,CPNE4" MicroRNA hsa-miR-190b:mirSVR_lowEffct hsa-miR-190b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.92E-97 2.19E-93 5.70E-96 5.25E-95 268 1639 "ACADM,CLK4,ACTN1,CCDC85A,ADD2,PLEKHH1,PWWP2A,HECW2,RTL9,HACE1,WDR35,SPARCL1,PCDH10,BBOX1,SEMA7A,MAP4K3,PARG,ASPA,NUMB,TMEM108,ZNF582,DPY19L3,BBS2,BCHE,MIR9-3HG,KSR1,FUBP1,C5,RAB29,LDLRAD4,CACNB4,KALRN,CAST,CBLN1,CCNH,RGN,MTMR7,P2RX6,LRBA,DCLK1,NUMBL,SRSF11,CHGB,SOCS6,CHN1,B4GALT6,RAB33A,MAP4K4,CNR1,CNTN1,AKAP7,IQCK,COL4A5,BAG4,ZFP28,SNCAIP,RGS6,VAC14-AS1,FAM169A,UBXN2A,CTH,PUM1,MYADM,SNPH,ZNF337,RASSF2,LONRF1,MATR3,KCTD8,DAPK1,ARMCX4,ARMCX2,ELMSAN1,JAKMIP2,HEPH,KIAA0319,SACS,MTX3,DOCK2,DUSP9,DNM1L,GOLT1B,ANKRD46,KLHL5,TMTC1,MBNL2,KMT5B,EGR3,TENM1,STARD3NL,C8orf37,EIF1,VPS13B,EPB41,LRRC17,DENND4A,ADGRV1,EYA1,TUBA1B,GTF2IRD2,FGF13,SCARA3,IP6K2,RGPD5,FOXO3,SLC37A3,NOP56,SMC2,PDLIM5,STAMBP,ERGIC3,MPP6,MEGF11,HRASLS5,GABRB3,ERAP1,ZNF559,DISC1,LRRC37A6P,MMADHC,TCERG1,COPS8,HPGDS,FUT10,RNF165,GUCY1A1,RASSF8,BACH2,SYNPO,LRRC75A,FAM69A,KCND2,KIF5A,KIT,A1BG-AS1,MAN2A2,MAT2A,TM6SF1,MEF2C,MGAT3,KITLG,SAMD5,NRBP2,LAYN,NEK1,CNOT4,SLC11A2,SETD4,LOC100128398,P2RX7,DPY19L2P2,PCSK1,PDE4D,ENPP2,ZDHHC8,ZNF655,SNX10,RETREG1,XRN1,MTRF1L,PURG,PMP22,EXOSC10,SDK2,KANSL1,RASGEF1B,PRKCB,MTMR10,PTPRE,PTX3,ZSCAN2,TUG1,CEP97,ZCWPW1,RASGRF2,RBBP6,HKR1,DPF2,RGS12,CCDC82,ROBO1,ROBO2,SGSM1,LRRK2,AP1AR,CSRNP3,SCP2,MRAS,SCAF8,SGK1,CPEB3,CHD9,ST6GAL1,SEC31A,SLA,FAM81A,SLC8A1,NAPB,SLC22A4,CPEB4,MAST1,ANKRD36,SNRPN,FAM126B,DOP1A,BDP1,ZHX3,UHRF1BP1L,CLASP2,ITPRID2,SAMSN1,SSTR1,LARP4,ELOVL4,DIP2A,PRRC2C,VPS13A,SYPL1,SYT1,COBL,PJA1,FAM208A,ADGRL3,KIAA1107,TBL1X,ATMIN,TCEA1,TCF4,DMXL2,TRIM2,SYNE1,TNS2,DICER1,ZFPM2,C18orf54,KAT6B,TP53BP2,TPM1,NPL,TRIO,PDSS1,TRPS1,ZNF610,FAM155A,EIF4ENIF1,UBE3A,BCL2L13,CCDC14,VSNL1,XPO1,XRCC4,PCDH20,KCNT2,NDRG4,LYPD6,DHX33,MAP3K12,CADM2,EVI5,PRDM8,MPPE1,DOCK8,RTN4,JMJD1C,KLHDC1,FXR1,NETO1,GAN" MicroRNA hsa-miR-16:mirSVR_highEffct hsa-miR-16:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.16E-97 2.89E-93 7.48E-96 6.88E-95 251 1441 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,ACTN1,GALNT13,AXIN2,ADRB2,AP2A1,AP2A2,SRPX,ARHGAP20,OGT,ANK2,BCAS1,PPFIA3,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,SLC4A4,TTLL9,MPDZ,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,CA8,CACNA1B,KALRN,PTBP2,CAST,RUNX1T1,ARHGEF1,CFL2,PPT2,CLCN3,TPP1,QKI,ARMC8,COL4A5,SLC4A8,ABI3BP,TBPL1,MYRIP,HAPLN1,CRYM,LRIG1,VCAN,SOCS5,ERC2,ARHGEF4,USP6NL,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,DCAF8,KCTD8,IP6K1,AIF1L,ARMCX2,YTHDC1,JAKMIP2,MYEF2,SPOCK3,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,PHF20L1,MBNL2,PLEKHA1,DENND4A,CEP85L,EYA1,NRN1,ACSL4,STRADA,FGFR1,PRKAG2,SUCO,RGPD5,SLC37A3,PDLIM5,CSPG5,NSG1,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,FERMT2,GPD2,PCLO,RNF165,RASSF8,ZHX1,FRMD3,MIER3,SHISA6,MSL1,RBPJ,NIM1K,INPP1,NME9,SLC35G1,KIF2A,KIF5A,LAMP2,PACRG,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MEST,MN1,THYN1,RTL5,NDP,NOVA1,SLC11A2,NTRK3,CNTN3,ETFRF1,PCDH9,PIK3R1,JAKMIP1,PSAT1,RETREG2,EPB41L4B,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,CNTLN,PTCH1,STK32A,ZSCAN32,PTPRD,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,KHDRBS2,ZDHHC14,RDX,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,ARMH4,FBXW7,ABCA11P,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN8A,COPZ1,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,ANKRD6,FAM81A,ARHGEF40,KBTBD4,SLC22A4,ZFP1,RCOR3,SNAP25,MBD5,RBM34,UNC5B,ZC3H13,TSPYL2,NFASC,RGL1,PRRC2C,SYNE2,SYPL1,SYT1,COBL,C12orf76,TAF9,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,SLC44A1,NR2E1,ERCC6L2,TPM2,RUNDC3B,LGI4,ZNF708,TRIM9,NDRG4,REEP1,EML6,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,RNF170,SNX14" MicroRNA hsa-miR-421:mirSVR_highEffct hsa-miR-421:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.13E-97 3.43E-93 8.87E-96 8.17E-95 246 1385 "CLK4,ADD1,RNF150,KLHL13,AGT,WDR35,OSBPL8,AK2,SPOP,SRPX,CEP126,FAM135A,DPP10,DDO,TNRC6C,ARNTL,CCDC74A,ZSCAN18,SLC4A4,BARD1,SEC11C,NRP2,GPC2,CA8,PTBP2,SLC25A14,RUNX1T1,CLDN10,LDB2,CFL2,SRSF11,CLCN3,QKI,CNTN1,ARMC8,AKAP6,LETMD1,MAGED1,RTTN,BAG4,ZFP28,CPS1,PREPL,ANKRD44,CS,SIPA1L1,PDE4DIP,APPL1,ZFYVE16,ZNF337,LONRF1,MAML1,DGKB,JAKMIP2,RHOBTB1,SNAP91,SACS,SPOCK3,FAM107B,USP3,DYNC1I1,NR1D2,DPP6,ECM2,DNM1L,PHC2,HIPK3,FCF1,FAM13A,KMT5B,PLXNC1,RCAN2,STX2,CDKL3,DNAJC27,FAM198B,CHST15,GORAB,SLC9B2,MED12L,OLFM1,POLR1B,FGF13,FGF14,FHL1,SUCO,UBE2E3,MEX3B,IP6K2,SEMA4D,ATP13A4,SLC37A3,COQ5,EFCAB2,TRMO,TMEM107,FAM49B,TPK1,ATP6V1H,ATP2C1,MSANTD4,OGA,HRASLS5,ERAP1,MTHFD2,ZNF559,LRRC37A6P,SRCAP,PCDH17,GPR75,ZNF638,GPD2,PRUNE2,FUT10,GRIK4,GRM8,FAM19A2,AP4S1,CFAP126,EID2B,LRRCC1,IL6ST,INPP1,IPO5,PACRG,SMAD1,MARK1,MEIS2,AFDN,ADAM22,NRBP2,TAGLN3,NEK1,CNOT4,NRCAM,SMIM11A,CLDN11,PRTG,PDE4B,PFKFB3,XRN1,GPSM2,STRN3,EPB41L4B,SH3KBP1,PPM1B,PPP2R5E,KANSL1,GRAMD1C,PRPSAP2,BCAS3,CNTLN,PTK2,PTPRB,PTPRD,PTPRO,RAD17,RASGRF2,RDX,GTDC1,RFX3,NUDT11,RNASEL,CCDC82,CARF,GSTCD,RORB,RPE,MCMBP,TCP11L1,ABCA11P,SEMA6D,ARX,HKDC1,ST6GAL1,ANKRD6,PPP4R3A,EPN2,SEPHS1,KBTBD4,SLC12A2,CPEB4,DMRTC1,LIMCH1,SNAP25,MBD5,BDP1,TROVE2,SAMSN1,SSTR2,ERBIN,ELOVL4,TTBK2,NSFL1C,SYNE2,ARHGEF9,PLCB1,SYT1,ANKRD28,MMS19,TACC1,ANKRD12,CAMTA1,DNMBP,ADGRL3,FBXW11,KLHL4,TCEA1,DMXL2,CUX2,ZEB1,TRIM2,SLC19A3,FAM200B,PMS2CL,ARL10,TMPO,TP53BP1,CDK20,C9orf85,SMUG1,NEIL2,AMACR,TSN,CA14,TTC3,TUBB2A,SGK3,CCDC14,VSNL1,CLDND1,XRCC4,ZIC1,ZIC2,MICU3,ZNF540,NDRG4,TCEAL7,FSTL5,SPIRE1,CADM2,LINC02210,FAM13C,ACTR3B,RNF146,GAN" MicroRNA hsa-miR-499-3p:mirSVR_highEffct hsa-miR-499-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.92E-97 3.87E-93 9.99E-96 9.19E-95 234 1252 "KCNH8,XKR4,TMCC3,BRAP,LRFN2,SLC24A4,ZNF608,INTS2,MTUS1,AK2,SEMA6A,MAP4K3,PPP4R4,MADD,TMEFF1,ARRB1,PLA2G4C,NCOA1,NUMB,SLC4A4,BARD1,NRP2,FUBP1,IL33,CACNA1B,KALRN,PTBP2,SEPT7,LRRFIP1,MAGI1,CDO1,SRSF11,FOXN3,B4GALT6,FHL5,ARHGEF6,FAM149A,AKAP6,RCHY1,RTTN,CNRIP1,SLC35F1,CPS1,SEC31B,C2CD2,GDA,SNCAIP,CSNK1G3,SOCS5,PDE4DIP,CTH,RIMS2,USP6NL,GPRASP1,GAPVD1,ARHGAP24,KCTD8,DAPK1,ARMCX2,SPATA2,ZNF804A,GSDME,POM121,SV2B,CPEB2,CASP8AP2,DPP6,SLC25A18,E2F6,EDN1,FRY,PHF20L1,SUGP2,MBNL2,EGR3,ASB3,EPHB1,IGSF6,CDKL3,EYA1,ABCA8,TAOK3,SCML2,DLC1,SPSB4,FGF13,FGF14,MAD2L2,AMOTL2,PRKAG2,FHL1,SUCO,UBE2E3,MEX3B,SEC23B,COQ5,UFM1,FAM49B,ERGIC3,CELF1,STAU2,ABLIM2,ZMAT1,GABRB3,GALC,MTHFD2,DISC1,GATM,SULT1C4,KDM2B,GPD2,PRDM5,GRM8,ZBTB49,RASSF8,ARHGAP36,ELOVL5,HMGCL,HNF4G,NEGR1,HSPA1L,ZNF181,IL6ST,ZNF678,JAK2,METTL21A,STXBP5,LAMP2,SYTL4,PIK3AP1,MARK1,MARK3,MAT2A,AQP11,LRP1B,KITLG,MID1,RTL5,NEK1,NF1,NFE2L2,NPR2,NTRK3,OPA1,CLDN11,GNG2,NALCN,ZNF655,RETREG1,XRN1,PURG,MAPKAP1,SCHIP1,ING3,PPM1B,MAPK9,GRAMD1C,DCHS2,RELN,CNTLN,BDNF-AS,TMEM260,PTPRD,C1orf109,TMEM255A,ZNF793,RAP1GDS1,ZNF493,MSANTD2,ZMAT4,FIGN,RFX2,SLC25A36,RNASEL,EXD2,CARF,GSTCD,RPS6KA2,LRRK2,RYR3,ZNF331,SEMA6D,FNIP1,MRAS,SHC4,HKDC1,ABLIM3,PPP4R3A,EPN2,RADIL,ZNF667,SNAP25,SNCA,TMCC1,BDP1,DOK5,SP4,ZNF423,SEPT8,DIP2A,PRRC2C,VPS13A,SYN2,ADGRL3,DMXL2,TRIM2,SYNE1,PUM2,C18orf54,ACTR6,PRRT1,RGMB,TRPS1,TSN,UBE3A,ZNF781,RICTOR,ZIC2,ZNF24,CELF4,ZBTB38,ZFAND5,SMARCAD1,EMSY,DNALI1,STOX2,ADAMTS9,MPPE1,FAM13C,KAT6A,SMIM8,JMJD1C,FXR1,NETO2" MicroRNA hsa-miR-3146:mirSVR_lowEffct hsa-miR-3146:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.13E-97 4.55E-93 1.17E-95 1.08E-94 238 1297 "ABCF1,CLK4,KDM5D,FMNL2,ADCY6,TMCC3,BRAP,PLEKHH1,INTS2,MTUS1,HECW2,HACE1,OSBPL1A,AK2,SPARCL1,SMIM17,ALCAM,SRPX,ANK2,EP400,CCDC146,LCORL,MAP4K3,BCAS1,TNRC6C,CDK13,SLC4A4,MYOM1,NRP2,BID,GPC2,WASF1,CA12,CACNB4,CABP7,ISPD,CBFA2T2,C1orf52,SEPT7,CCPG1,CLGN,FOXN3,CHGB,TPP1,ARMC8,SUMF2,SLC4A8,RCHY1,C2CD2,CRHBP,ANKRD44,NCOR1,CLIP3,CRYM,OSBPL3,CSNK1G3,SOCS5,FAM169A,DZIP3,UBXN2A,PHF14,ZSCAN23,MAML1,BRINP1,ELMSAN1,MYEF2,ELMO1,SPOCK3,TMCC2,EXOG,EBF1,FSD1L,OPTN,FAM13A,EGR3,KCTD3,EIF4G2,RGS17,EPHB1,STX2,SRRM1,ANKMY1,MRVI1,NSRP1,CHST15,SEC24B,SYNCRIP,FOXO3,PDLIM5,CELF1,MEGF11,GABBR1,GABRG1,DENND2A,GCNT2,GDF9,RNPS1,SPIN1,MSL3,LUZP2,TDRKH,STON1,TMEM121B,PCLO,SPACA9,BTN2A1,ZBTB49,PSIP1,HLF,IRF8,KCND2,CREG2,KIF2A,LAMP2,LIFR,PAXBP1,LYPLAL1,MBNL1,CHIC1,TM6SF1,LRP1B,AFF1,XRRA1,MX1,LYRM9,MYO5A,MYO7A,NACA,NEK1,CNOT4,NOVA1,NTRK2,IGSF11,OPA1,ZNF713,GLIPR1L2,PCDH9,PRTG,GPR85,DUSP26,SNX10,ZFYVE21,XRN1,STRN3,MAGEL2,ING3,EPB41L4B,MINDY2,PPP2R5E,KANSL1,PRKACB,CEP41,SLC26A11,QRICH1,PTCH1,TMEM260,ZSCAN32,PTPRB,PID1,ZNF493,RBBP6,KHDRBS2,RDX,REV3L,RGS12,SLC25A36,RNASEL,ZFHX4,LGI2,DCUN1D2,TMLHE,ROBO2,PCMTD2,BAALC,LRRK2,KCNIP3,RTN1,CCDC112,TRAPPC13,SATB1,ATXN2,SCN7A,CASC3,FERMT1,CPEB3,SHC4,HKDC1,ST6GAL1,NLGN1,PPP4R3A,KDM4D,CCDC88A,KBTBD4,CPEB4,RCOR3,LIMCH1,SNAP25,SNRPN,SP4,HECW1,ERC1,CDK19,SPART,DIP2A,SULF2,KLHL7,SYNE2,ARHGEF9,PLCB1,TACR1,AGTPBP1,CUX2,CLASP1,CCDC173,FAM200B,DICER1,SIRT1,NR2E1,TP53BP2,NPL,RPL7L1,FAM155A,BCL2L13,CCDC14,PCDH20,TRIM9,ZBTB38,FSTL5,RNF103,HPS4,PLSCR4,DOCK8,ST7,HNRNPA3,FBXO36,ADAMTSL3,SOCS4,ST8SIA2" MicroRNA hsa-miR-4299:mirSVR_lowEffct hsa-miR-4299:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.37E-97 5.24E-93 1.34E-95 1.24E-94 275 1730 "KCNH8,SYS1,ACTN1,FMNL2,GALNT13,ADD2,UNC5A,RNF150,BEND6,CC2D2A,TAOK1,C1QTNF1,SPARCL1,PCDH10,BBOX1,ZFAT,CDC42BPA,FGD2,SUGT1P4-STRA6LP-CCDC180,KCNAB2,NT5C3B,USP37,LGR5,CDK10,PLA2G4C,ZSCAN18,NUMB,DPY19L3,ADAM23,BACH1,ADGRB3,BBS2,SYNJ2,ARHGEF7,SCAPER,CASTOR3,SGCE,CALB1,KALRN,PTBP2,CAMK2G,LDB2,CD38,ARHGEF2,CDH2,LRRFIP1,L3MBTL4,CHGB,ASIC3,CHN2,NDST3,MAP4K4,AKAP5,COX4I1,TOGARAM2,CDC42BPB,AKAP12,HINFP,SUSD5,VCAN,PPP1R16B,PLCXD3,CTH,ZSCAN23,DCAF4,ARHGAP32,TM9SF4,SPATA2,ZNF804A,ELMO1,MFAP3L,RUSC2,TMCC2,WDR20,CHRDL1,GRIN3A,CD99L2,RPS6KL1,DPH1,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,EGR3,COPS4,PLEKHA1,ELN,VPS13B,MFSD10,EPHB1,SRRM1,TLR7,RASL12,MRVI1,EZH1,TAOK3,CORO2B,ST3GAL6,CEP78,FCGR1B,SEC24B,FER,PRKAG2,POLK,FOXO3,FLT1,NELFCD,FOLR2,TMEM175,TRMO,POMT1,UFM1,PDLIM5,KHDRBS3,STAU2,MEGF10,CHL1,IP6K3,CPLX1,PCDH17,MALT1,BRD8,CRCP,TCERG1,COPS8,TNRC6A,POLL,KCNMB4,DCLK2,LOXL3,GPR12,TMEM121B,PCLO,GRIN2D,BTN2A1,KAT7,RNFT2,GUCY1A1,PADI2,SYNPO,HMGCL,SHISA6,CELF5,SMAP1,IDH3B,C2orf72,LRRC25,GAREM2,RBPJ,LRRCC1,KIAA1755,SCIN,IL6R,ZNF678,INPP5B,KCNJ16,STXBP5,MAN2A2,MAPT,MBP,TM6SF1,MEIS1,MID1,MPP2,BLOC1S2,MYO6,OGG1,ZNF713,GLIPR1L2,CNTN3,PDE3A,PFKFB2,ZNF655,PRIMPOL,PRKCB,CNNM2,CNTLN,ANKHD1,BDNF-AS,PTPRB,PTPRE,ZSCAN2,IQSEC3,ZCWPW1,ENOX1,OXR1,RASGRF1,RASGRF2,ERI2,GTDC1,RIC8B,RNASEL,LGI2,CCDC82,ROBO2,ATP8B4,ADAL,RPS20,ZNF331,SEMA6D,ATXN7,PRCD,TNFRSF19,GALNT10,KIF16B,FNDC3A,SLC2A5,PEX26,SLC8A1,KBTBD4,CPEB4,ARFGAP1,EPC1,GKAP1,ANKRD36,LIMCH1,SNRPN,FAM126B,USP33,DOK5,NMNAT2,ZNF423,SPTAN1,IQSEC2,TSPYL2,DDN,SPART,NFASC,ZC4H2,NKAIN2,SEPT8,RGL1,ADHFE1,KANK1,SULF2,SYNE2,PLCB1,SYN1,ARC,TACR1,TCF4,SIN3B,TPCN2,TRIM2,NAT16,DOCK9,ARHGAP9,SIK3,ITGB3BP,AP4E1,AKTIP,NR2E1,FAM124A,RASD2,C9orf85,ZNF346,ELP5,TRPS1,UBE3A,OSBP2,WRN,CLDND1,ZNF711,ZBTB38,POLR3H,LAMP5,EMSY,SLC38A1,STOX2,SLC17A7,MPPE1,WNK3,JMJD1C,FXR1" MicroRNA hsa-miR-1975:mirSVR_lowEffct hsa-miR-1975:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-96 8.02E-93 2.05E-95 1.89E-94 250 1436 "ABR,CLK4,NCKAP5,TMEM132B,ADCY6,AMPD2,OGT,SUGT1P4-STRA6LP-CCDC180,APAF1,SHROOM2,SPTBN4,ARRB2,CHID1,ATP1A3,SLC4A4,ZNF583,RIPK1,KSR1,BTK,MTMR3,PRMT9,LDLRAD4,CFAP410,KALRN,PTBP2,CAPN3,CBS,LDB2,MAGI1,MS4A7,ARHGAP22,PPT2,MAP4K4,IGLON5,AKAP7,COL4A5,COL11A2,RCHY1,SLC35F1,FAM171B,RNF14,HINFP,CS,CSF1,FAM169A,SLITRK5,PPP1R16B,APPL1,DCAF4,ARHGAP32,LONRF1,TM9SF4,SCRN1,GIT2,SPATA2,DCTN1,MFAP3L,DDX46,EXOG,GRIN3A,DNM1,NYAP1,USP3,DPP6,DPYSL2,DRP2,TOM1,MAMLD1,ABCC5,AASDH,EDN1,HIPK3,FCF1,TMTC1,CELSR3,EGR3,RASA4,EIF4G2,IRAK4,LRRC17,MTSS1L,DENND4A,NCALD,NRN1,TBC1D16,TUBB3,ZMYND10,ZNF589,FER,HPCAL4,SYNCRIP,FLT1,CAMKK2,ATP2C1,ERGIC3,CELF1,SDCBP2,TMEM8B,DISC1,CPLX2,CYP46A1,USP19,GHR,TTBK1,CRCP,GLI2,RAB30,TNRC6A,GPD1,STMN2,PLCD4,ATE1,GRM2,CIT,BTN2A1,RNF165,GSTM5,RNFT2,HAS2,MAN1B1,ATXN2L,ARHGAP36,ELOVL5,DHX35,LRRC75A,CELF5,MSL1,ZNF546,KHK,TTYH2,SFXN5,MAP2,MAPT,ADAM11,MEF2C,MIA2,SCAMP5,SAMD5,HS6ST3,NFIX,NNAT,NPTX2,SMIM11A,NTRK3,CLDN11,CNTN3,PDE4B,PDE1B,PFKFB4,OLA1,PIK3R1,TMEM38A,PLCD1,SMIM7,STRN3,SCHIP1,SEPT4,MBOAT7,POLR2F,FSD1,MINDY2,NKAIN4,PPP5C,PRKAB2,MASP1,CNNM2,APTX,TMEM104,ZIK1,PTPRN2,FAM66C,IQSEC3,NWD1,ENOX1,PRRT2,RGS4,KCTD17,MRPS18A,NUDT11,PBRM1,SUGCT,KLHDC8A,PNMA8A,GSTCD,HUNK,ST6GALNAC6,CLIP1,RXRA,NCBP3,SCN2B,ZFP2,PEAR1,CASC3,GALNT10,RASA3,CHD9,FAM81A,PEX26,PPP4R3A,KBTBD4,SLC12A2,SLC12A4,EPC1,SMARCD3,INAVA,TRERF1,ZSWIM8,SPTAN1,LMO3,PBLD,POGZ,ZC4H2,STXBP1,JMJD6,NUDT10,ANKRD28,C12orf76,TBCEL,FBXW11,SIN3B,ZFP90,TCF12,CLASP1,SZT2,DOCK9,FRYL,MTMR14,TK2,TNS1,AMACR,RUSC1,TSC1,SSBP2,MGAT5B,MTCH1,XPO1,ZNF24,TRIM9,LYPD6,DPYSL5,MEIS3,DHX33,URM1,SLC17A7,WNK3,EPM2A,ACTR3B,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-519a:mirSVR_lowEffct hsa-miR-519a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-96 8.23E-93 2.10E-95 1.93E-94 274 1721 "SYS1,GALNT16,CCDC85A,ADD1,USP31,RNF150,PTCHD1,ADRA1B,BEND6,HECW2,WDR35,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,TNRC6C,CDK10,PLA2G4C,MARCH3,NCOA1,NUMB,INSYN2B,DPY19L3,ADGRB3,RGS11,BCL7A,FUBP1,MTMR2,SGCE,CACNB4,CALM1,KALRN,CAMK2G,CBFA2T2,C1orf52,NOG,MS4A7,B4GALT6,EPS15L1,CLTC,QKI,CNR1,IQCK,PCYT1B,ZFP28,CNRIP1,HAPLN1,TRIM69,PDE4DIP,CNTNAP2,FAM169A,APPL1,RUBCN,MYADM,GAPVD1,ZNF337,DGKB,DGKG,DNAL1,SPATA2,MFAP3L,ZC3H11A,GUCD1,RHOBTB1,SNAP91,HS3ST2,DMTF1,SLC25A18,ACOT8,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,PAN3,EMX2,ERBB4,MRPL37,TLR7,KATNAL1,ST3GAL6,MED12L,POLK,SEC23B,PCYOX1,SYNCRIP,ATP13A4,ANKFY1,NOP56,CELF1,GAD1,ZNF274,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,TNRC6A,MSL3,CBX1,GPT2,ADGRA3,GPD2,GPR34,PCLO,ZNF496,SOX21,GUCY1A1,IRAK3,HNF4G,DHX35,SHISA6,CELF5,SMAP1,IGF1,INPP5B,SLC35G1,KIT,LAMP2,CAMK2N2,SFXN5,LMO2,ZNF667-AS1,MAP2,MAP6,SCAMP5,AFF1,PTOV1,NRBP2,TAGLN3,MXI1,LYRM9,MYO9A,P2RY13,NBL1,NCF2,SFR1,NFIX,NPTX2,NTRK2,NUCB2,OPRL1,PAX6,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,DUSP26,XRN1,GPSM2,SLC25A23,LRP12,SDK2,ING3,MINDY2,CCDC144B,MAPK3,MAPK4,DEF8,MTMR10,PTPRD,PTPRE,FAM184A,RBBP8,RADX,REV3L,GTDC1,PRIMA1,LGI2,ROBO2,ELP2,NEK11,FBXW7,ZC3H14,GLDN,RPS20,CLIP1,ZNF331,SATB1,SCN2B,TNFRSF19,PEAR1,PUF60,FBXO11,NUBPL,WDR37,BTBD3,WDR47,SLC6A8,KDM4D,SLC8A1,SLC11A1,SLC12A2,NAPB,TET1,CPEB4,ZNF667,TTC17,SNAP25,SNCA,MBD5,PDZD2,FNBP1,SP4,UHRF1BP1L,KDM4C,ZBTB43,TSPYL2,RBM26,NFASC,SEPT8,DIP2A,SYN2,TACC1,MTCL1,EXOC7,ATMIN,TCF4,CUX2,ZEB1,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,ITGB3BP,AP4E1,TIAM1,TMPO,RIMBP2,RGMB,SMUG1,RUNDC3B,TRPS1,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,WIPF1,CLDND1,MICU3,KCNT2,LYPD6,ZBTB38,EMSY,SLC38A1,EVI5,STOX2,PRDM8,SLC17A7,FAM13C,FZD3,ST7,UBE3B,FBXO36,FAM219B,NLRP3,TTC7A,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-miR-206:mirSVR_lowEffct hsa-miR-206:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-96 9.17E-93 2.33E-95 2.15E-94 283 1833 "SYN3,EMILIN3,SYS1,FMNL2,KLHL32,OLMALINC,INTS2,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,HFM1,PCDH10,UNC79,FAM135A,ZNF687,AMPH,AMT,CDC42BPA,LRCH2,VAT1L,TNRC6C,LGR5,PPP4R4,CASK,TMEFF1,ARNTL,CHRD,DYNLL1,RNF182,ATP6V0A1,TTLL9,ADGRB3,BCL7A,SYNJ2,ARHGEF7,SCAPER,MTMR3,GYG2,SGCE,C5,WASF1,CA12,CACNA1A,CALB1,PTBP2,PRC1,METTL6,ENTPD6,CDH2,SRSF11,QKI,AKAP6,LETMD1,AKAP5,TBPL1,SMARCAL1,CLOCK,CRHBP,AKAP12,ANKRD44,CSF1R,CNTNAP2,SLITRK5,KIAA0040,PHF14,ARHGEF4,RIMS2,GPSM1,ARHGAP32,HDAC4,TBC1D5,AIF1L,PITPNC1,ZBTB24,MYEF2,KIAA0319,SPOCK3,FAM107B,KIF19,DMPK,HS3ST2,USP3,CDON,GOLT1B,EBF1,EDIL3,HEYL,KLHL5,TMTC1,YAF2,KCTD3,EIF4G2,EIF5,PLEKHA1,RGS17,EMX2,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,CLVS1,FAM198B,RPS6KC1,SH3YL1,PTK2B,TAOK3,FCGR1A,ZNF589,FGF14,FGFR3,BAIAP2,RGPD5,SLC37A3,FLYWCH1,PDLIM5,DLL3,GALNT15,ZNF274,DISC1,CPLX2,IGSF5,TUBGCP4,MSTN,LYVE1,NTNG2,TOX3,KDM2B,GNG4,FUT10,GRIA2,PRDM5,BTN2A1,GSTM5,ADAMTS6,IRAK3,UBE2QL1,PADI2,BACH2,ELOVL5,ACOT7,HNMT,LRRC75A,SMAP1,IRF8,FAM95B1,KNDC1,LRRCC1,IL6ST,INPP5B,ITPKB,LIFR,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,AFF1,GIT1,SAMD5,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM2,ALDH1L2,VWA2,ZNF827,GLIPR1L2,PAX6,PRTG,GPR85,FAM218A,PMP22,EPB41L4B,PPP2R2B,PPP2R2C,VSTM2L,WBP1L,CNTLN,PTPRN,ZNF793,FAT4,SUSD4,ZDHHC14,REV3L,RGS3,RIC8B,ZFHX4,CYB561D1,NEK11,ZNF671,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,ATXN2,LRFN5,GALNT10,SUPT20H,SGK1,KIF16B,CHD9,FBXO11,ST6GAL1,SYBU,NUBPL,PPP4R3A,SLC6A8,SLC9A5,SLC12A2,ZFP1,SMARCA4,SMARCC2,LIMCH1,MAPKBP1,TMCC1,FAM126B,DOP1A,NMNAT2,HECW1,NFASC,POGZ,MPRIP,ELOVL4,KANK1,SEPT3,SUPT5H,SYNE2,SYN1,C12orf76,TAL1,AGTPBP1,SATB2,TPCN2,SYNE1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,CCDC173,ZFPM2,AP4E1,TK2,ACTR6,TLR4,BEX4,RIMBP2,CSMD1,KAT6B,PIK3R5,STXBP4,ANKRD20A2,TTTY15,RPRM,FLRT2,VSNL1,RICTOR,GUSBP1,ZIC1,ZNF711,ZNF24,MKRN3,ZBTB38,ANKS1B,UPF3A,FIP1L1,ST7,KAT6A,HNRNPA3,RNF170,TTC7A,FXR1,NETO1,ST8SIA2,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-548q:mirSVR_lowEffct hsa-miR-548q:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-96 9.39E-93 2.38E-95 2.19E-94 250 1437 "DGCR6,ASIC1,ACTN1,FMNL2,GALNT13,ADORA2A,PTCHD1,SLC24A4,KIAA1324,SEMA6A,ARHGAP20,OGT,FGD2,UPRT,CDK10,CDK13,MARK4,NCOA1,DPY19L3,MYOM1,DOCK11,ADAM23,TTLL9,BACH1,LINC00847,SYNJ2,ARHGEF7,CA4,VXN,ISPD,SPAG9,CLDN10,ARHGAP33,TIGD7,CHRNA4,TPP1,DGCR9,QKI,SRP14-AS1,HECTD1,CNGA3,FAM149A,AKAP6,RCHY1,TBPL1,TOGARAM2,CNRIP1,ENTPD4,CRHBP,GDA,CLIP3,ABCG1,CSF2RA,SOCS5,CST3,CTH,GREB1,SEC14L5,TM9SF4,MATR3,MAML1,IST1,GIT2,PITPNC1,MFAP3L,C2CD2L,MED12,PDCD6IP,DTNA,MAMLD1,DNAJB6,FCF1,HEYL,RASA4,ASB3,EIF5,TNK2,ELN,C3orf18,DCTN4,EIF1,ENO2,EPB41,LRRC17,MTSS1L,REEP2,CORO2B,ST3GAL6,CEP78,FCGR1B,STRADA,ZNF589,OLFM1,AMOTL2,MEX3B,HPCAL4,EVL,TPK1,CAMKK2,KHDRBS3,RAPGEF6,IP6K3,IQGAP2,ERAP1,LRRC37A6P,CPLX1,GATM,ALDH1L1,ADAM28,GFRA2,PCDH17,PPARGC1A,MALT1,BRD8,CRCP,GLI2,CBX1,KDM2B,KCNMB4,FERMT2,GPT2,GPR37,PCLO,GRB10,GRM2,RABL2A,ADAMTS6,ZHX1,MIER3,HMGCL,CPT1C,FAM95B1,RBPJ,KNDC1,ZNF678,GATD1,STXBP5,MAN2A2,MAP2,MBNL1,MEIS1,AFF1,XRRA1,MOV10,MXI1,ZC3H12B,NNAT,NME4,SLC11A2,NUCB2,DPY19L2P2,CDK18,PDE3A,NALCN,PLCB2,SLC25A23,SCHIP1,SEPT4,KANSL1,VSTM2L,CEP41,EPDR1,HYDIN,TMEM104,PIGG,CNTLN,PTCH1,BDNF-AS,TMEM260,PTPN13,PTPRE,C1orf109,TUG1,SLC25A48,RASGRF2,MSANTD2,TRIM68,ERI2,UBR7,RGS12,CYB561D1,RORB,MCMBP,ADAL,RPS20,ATAT1,KCNIP3,NCBP3,SAFB,SALL1,ATXN7,FERMT1,NLGN1,WDR37,SLC11A1,NAPB,CPEB4,EPC1,RCOR3,KIF13A,CABCOCO1,SNRPN,NMNAT2,TEX2,PEG10,DBNDD2,SPTB,CDK19,ATP10B,PBLD,ST5,SEPT8,RGL1,NECAB1,SYN2,SLC37A2,ASTN2,TACC1,MLST8,TBCEL,TCF4,TRIM2,HIF3A,AP4E1,TMEM9,TK2,BHLHB9,RIMBP2,KAT6B,PIK3R5,TPM1,CDK20,RGMB,HSPBP1,RPL7L1,OSBP2,FLRT2,XRCC4,ZFP37,ZNF74,ZBTB38,ANKS1B,ZNF213,ZFAND5,TMEM178A,CIAPIN1,FIP1L1,RGS7BP,JMJD1C,IFT88" MicroRNA hsa-miR-590-5p:mirSVR_lowEffct hsa-miR-590-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-96 9.52E-93 2.41E-95 2.22E-94 255 1495 "GALNT13,ADRB2,HECW2,ALCAM,PCDH10,FAM135A,GPRASP2,SYT13,SEMA7A,PKP4,EPB41L5,APOC1,CDC14B,STK33,NUMB,TMEM108,RNF182,DOCK11,TTLL9,ADGRB3,BCHE,SYNJ1,NAE1,CACNA1G,THSD7A,KALRN,SPAG9,CBR1,L3MBTL4,CDO1,COPB2,RAB28,CLTC,CNN3,FAM149A,AKAP5,MYRIP,SEC31B,AKAP12,RNF14,ANKRD44,LRRC3B,CSNK1G3,APPL1,PLCXD3,RUBCN,HDAC9,TCAF1,ZFYVE16,TBC1D5,LIN54,MATR3,KCTD8,SCRN1,ARMCX2,MFAP3L,DDX46,POM121,RHOBTB1,SPOCK3,DLX1,HS3ST2,MED12,DMTF1,SLC12A6,ACOT8,PDCD6IP,ECM2,DNAJB6,ABCC5,E2F5,SNX29,FRY,OPTN,EGFR,MBNL2,EIF4G1,COPS4,USPL1,FCGR1A,FECH,SLC9B2,MED12L,PRKAG2,SUCO,SYNCRIP,FOXO3,ANKFY1,SLC37A3,NBEA,STAMBP,KHDRBS3,CSPG5,HRASLS5,TRAF3IP2,RAPGEF6,C15orf41,GATM,GCNT2,FREM1,GGTA1P,GLYR1,MSL3,GLUL,ZNF638,FERMT2,ADGRA3,STON1,GPR34,PCLO,BTN2A1,BVES,AP4S1,HAS2,ZHX1,BACH2,HMGCR,EID2B,MSL1,ZIC5,LRRCC1,ZNF678,ITGAM,CDH20,KCND2,PACRG,MBD1,MBP,CHIC1,SHC3,MEF2C,MEIS2,KCTD6,MSR1,LAYN,MYO6,MYO9A,NEK1,ALDH1L2,NOVA1,NTRK2,OXTR,ETFRF1,PCDH8,PDE3A,PDE4D,PDPK1,PFKFB2,SERPINI1,PIK3C2A,FAM218A,RETREG1,SLC25A23,LRP12,MBOAT7,IRX1,MINDY2,PRKAB2,RASGEF1B,PRKCB,MAPK9,GRAMD1C,CNTLN,PTK2,PTPN13,PTX3,TUG1,FAM66C,ZCWPW1,RBBP6,ZDHHC14,RDX,RET,ERI2,FIGN,TMLHE,PNMA8A,CCDC102B,LRRK2,ZNF568,CCDC112,CSRNP3,LRFN5,SCN7A,SCN8A,KIF21A,SH3GL3,SHC4,NLGN1,DZIP1,WDR47,SLC6A11,KBTBD4,BTBD7,ZFP1,CDK5RAP2,ANKRD36,MBD5,SNRPN,FNBP1,GLT8D1,HECW1,UHRF1BP1L,ZBTB43,RBM26,SSTR2,ELOVL4,CEP68,PHLDB1,STXBP1,KLHL7,NECAB1,JMJD6,PLCB1,SYPL1,TCF4,RPGRIP1L,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,RNF216P1,AP4E1,ZMAT3,ZNF106,ACTR6,CSMD1,TP53BP2,METTL3,STXBP4,SSBP2,CLHC1,SLC35A4,CLDND1,XPO1,MICU3,ZNF74,ZBTB38,REEP1,FSTL5,EML6,SMARCAD1,INTS3,CADM2,SLC38A1,FAM47E,KAT6A,SMIM8,RNF170,FXR1,NETO2,JPH3" MicroRNA hsa-miR-199b-3p:mirSVR_lowEffct hsa-miR-199b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.62E-96 1.47E-92 3.69E-95 3.40E-94 243 1360 "ACADM,GALNT16,PLEKHH1,PTCHD1,BEND6,INTS2,HECW2,TBC1D14,OSBPL8,TXNDC16,CC2D2A,ARHGAP20,FAM135A,ZFAT,LCORL,PKP4,APBB2,USP37,TMEFF1,ZFYVE28,ARNTL,NUMB,N4BP2L1,CFLAR,IL33,CACNB4,CALB1,CAMK2G,VXN,PRC1,CBFA2T2,ARHGEF2,LOC730101,CCPG1,NOG,NUMBL,NRXN3,PLAA,PPT2,CLCN3,C4orf33,PCYT1B,SLC4A8,MAGED1,RCHY1,CDC42BPB,RBM39,AKAP12,NCOR1,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,CCDC144A,HDAC9,TBC1D5,TMEM170A,GIT2,ARMCX2,KLHL3,RHOBTB1,SEC16A,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,ENO2,EPHB1,ERBB4,PIPOX,F5,FAM198B,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,RGPD5,FLT1,UFM1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,KHDRBS3,NSG1,MPP6,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GNAL,LNX1,PRUNE2,TPPP,GRB10,CIT,KAT7,ZBTB49,FAM222A,IRAK3,FRMD5,MAN1B1,TJAP1,KCND2,KIF5A,IPO5,STMN1,ZFYVE27,MAPT,MBD1,LRP1B,MEF2C,PPM1L,AFDN,ZNF680,BLOC1S2,LYRM9,LAYN,P2RY13,NFYA,SLC11A2,NTRK2,SETD4,IGSF11,OPA1,GPR137C,SEMA5B,PIK3R1,CCSER2,ZFYVE21,PKM,STRN3,FA2H,PPM1B,TATDN3,CCDC144B,PPP3CA,PRKACB,MAPK4,HYDIN,VPS13C,WDR25,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,PTX3,ZNF615,TUG1,FAM66C,FAM184A,RAP1GDS1,KHDRBS2,RGS3,RIC8B,TMLHE,EXD2,ROBO2,TCP11L1,ABCA11P,ZNF331,ATXN7,TNFRSF19,TRA2B,SHC4,FBXO11,CCDC92,NLGN1,ANKRD6,PEX26,SLC12A2,KDM4B,BDP1,RBM26,ATP10B,CLSTN2,ITPRID2,SSTR1,LARP4,STAU1,RGL1,DIP2A,STAC2,ADHFE1,KLHL7,FAM208A,ADGRL3,FBXW11,SIN3B,ZEB1,TPCN2,DOCK9,DNAH7,ZFPM2,ITGB3BP,ZNF106,AKTIP,MTMR14,NACC2,RIMBP2,DCBLD1,TTC3,USP1,CFAP298,PCDH20,ZFP37,ZNF711,SLC38A1,EVI5,STOX2,CIAPIN1,NAV3,FAM47E,PDSS2,DNAH10,PHTF2,JMJD1C,TIGD6,MSRB3,SOCS4,CPNE4" MicroRNA hsa-miR-199a-3p:mirSVR_lowEffct hsa-miR-199a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.62E-96 1.47E-92 3.69E-95 3.40E-94 243 1360 "ACADM,GALNT16,PLEKHH1,PTCHD1,BEND6,INTS2,HECW2,TBC1D14,OSBPL8,TXNDC16,CC2D2A,ARHGAP20,FAM135A,ZFAT,LCORL,PKP4,APBB2,USP37,TMEFF1,ZFYVE28,ARNTL,NUMB,N4BP2L1,CFLAR,IL33,CACNB4,CALB1,CAMK2G,VXN,PRC1,CBFA2T2,ARHGEF2,LOC730101,CCPG1,NOG,NUMBL,NRXN3,PLAA,PPT2,CLCN3,C4orf33,PCYT1B,SLC4A8,MAGED1,RCHY1,CDC42BPB,RBM39,AKAP12,NCOR1,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,CCDC144A,HDAC9,TBC1D5,TMEM170A,GIT2,ARMCX2,KLHL3,RHOBTB1,SEC16A,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,ENO2,EPHB1,ERBB4,PIPOX,F5,FAM198B,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,RGPD5,FLT1,UFM1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,KHDRBS3,NSG1,MPP6,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GNAL,LNX1,PRUNE2,TPPP,GRB10,CIT,KAT7,ZBTB49,FAM222A,IRAK3,FRMD5,MAN1B1,TJAP1,KCND2,KIF5A,IPO5,STMN1,ZFYVE27,MAPT,MBD1,LRP1B,MEF2C,PPM1L,AFDN,ZNF680,BLOC1S2,LYRM9,LAYN,P2RY13,NFYA,SLC11A2,NTRK2,SETD4,IGSF11,OPA1,GPR137C,SEMA5B,PIK3R1,CCSER2,ZFYVE21,PKM,STRN3,FA2H,PPM1B,TATDN3,CCDC144B,PPP3CA,PRKACB,MAPK4,HYDIN,VPS13C,WDR25,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,PTX3,ZNF615,TUG1,FAM66C,FAM184A,RAP1GDS1,KHDRBS2,RGS3,RIC8B,TMLHE,EXD2,ROBO2,TCP11L1,ABCA11P,ZNF331,ATXN7,TNFRSF19,TRA2B,SHC4,FBXO11,CCDC92,NLGN1,ANKRD6,PEX26,SLC12A2,KDM4B,BDP1,RBM26,ATP10B,CLSTN2,ITPRID2,SSTR1,LARP4,STAU1,RGL1,DIP2A,STAC2,ADHFE1,KLHL7,FAM208A,ADGRL3,FBXW11,SIN3B,ZEB1,TPCN2,DOCK9,DNAH7,ZFPM2,ITGB3BP,ZNF106,AKTIP,MTMR14,NACC2,RIMBP2,DCBLD1,TTC3,USP1,CFAP298,PCDH20,ZFP37,ZNF711,SLC38A1,EVI5,STOX2,CIAPIN1,NAV3,FAM47E,PDSS2,DNAH10,PHTF2,JMJD1C,TIGD6,MSRB3,SOCS4,CPNE4" MicroRNA hsa-miR-15b:mirSVR_highEffct hsa-miR-15b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.95E-96 2.21E-92 5.55E-95 5.11E-94 251 1454 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,CCDC85A,GALNT13,AXIN2,ADRB2,AP2A1,AP2A2,SRPX,ARHGAP20,OGT,ANK2,BCAS1,PPFIA3,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,TTLL9,MPDZ,NRP2,CFLAR,SYNJ1,FUBP1,SCAPER,MTMR3,CA8,CACNA1B,KALRN,CAST,RUNX1T1,ARHGEF1,TIGD7,CHRNA4,PPT2,CLCN3,QKI,HECTD1,SLC4A8,TBPL1,MYRIP,SEC31B,PREPL,CRYM,LRIG1,SOCS5,PDE4DIP,ERC2,USP6NL,ARHGAP32,KATNAL2,RIPOR2,DCAF8,KCTD8,IP6K1,ARMCX2,YTHDC1,JAKMIP2,SPOCK3,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,ACOT8,FAM78B,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,PHF20L1,MBNL2,PLEKHA1,PAN3,RCAN2,GPHN,DENND4A,CEP85L,SPEG,EYA1,NRN1,ACSL4,RACK1,FGFR1,PRKAG2,SUCO,MEX3B,RGPD5,SLC37A3,PDLIM5,CELF1,CSPG5,NSG1,OGA,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,FERMT2,GPD2,RNF165,RASSF8,ZHX1,FRMD3,MSL1,RBPJ,NIM1K,SCIN,ZNF678,INPP1,NME9,SLC35G1,KCND2,KIF2A,KIF5A,LAMP2,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,MSR1,THYN1,RTL5,NDP,SLC11A2,NTRK3,GPR137C,CNTN3,ETFRF1,PCDH9,PDE3A,PDE4D,PDPK1,SLC10A4,PIK3R1,JAKMIP1,PSAT1,RETREG2,EPB41L4B,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,CNTLN,PTCH1,STK32A,ZSCAN32,PTPRD,PID1,TMEM255A,FAT4,RBBP6,ZDHHC14,RDX,RET,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,RPL15,ARMH4,FBXW7,ABCA11P,KCNIP1,ZNF568,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN8A,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,ANKRD6,FAM81A,BTBD3,ARHGEF40,KBTBD4,SLC22A4,CPEB4,RCOR3,SNAP25,MBD5,SNRPN,UNC5B,ZC3H13,TSPYL2,RBM26,NFASC,ADHFE1,PHLDB1,PRRC2C,SYNE2,VPS13A,SYPL1,C12orf76,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ERCC6L2,KAT6B,TP53BP2,NPL,TPM2,RUNDC3B,LGI4,ZNF708,TRIM9,EML6,ANKS1B,SLC30A4,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,SNX14" MicroRNA hsa-miR-888*:mirSVR_highEffct hsa-miR-888*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-96 2.38E-92 5.98E-95 5.50E-94 222 1133 "CLK4,PLEKHH1,FAHD2CP,MTUS1,OGT,LCORL,PPP4R4,CDK13,NUMB,RASL11B,CCAR2,ATP1A3,ATP1B3,STX16,ADAM23,ADGRB3,MPDZ,ZNF599,PROM1,SYNJ1,SCAPER,CA8,KALRN,PTBP2,NOG,SRSF11,PPT2,C4orf33,SULT4A1,FAM149A,AKAP6,AKAP5,RCHY1,COX4I1,ZFP28,SLC35F1,CPS1,FAM171B,SH2B1,CRMP1,ARHGEF10,KIAA0040,PHF14,RIMS2,CYBB,DOCK4,HDAC9,GAPVD1,PABPC5,ZC3H11A,EXOG,CPEB2,RCAN1,E2F6,EBF1,EDIL3,EDNRA,EDNRB,CNNM1,KMT5B,TMEM35A,CALCRL,EMX2,EPB41,COQ7,RCAN2,RABEPK,DENND4A,EXTL2,EYA1,CLVS1,MED12L,OLFM1,FGF13,SUCO,UBE2E3,SYNCRIP,NELFCD,JKAMP,ST6GALNAC3,STAU2,MSANTD4,SARAF,ABLIM2,FYB1,GABRG2,C15orf41,DISC1,KIAA1841,SESN1,PPARGC1A,BRD8,COPS8,GPR75,ZNF638,CBX1,DCLK2,LNX1,GSN,ZBTB49,SOX21,HAS2,ARHGAP36,MIER3,SHISA6,ZNF181,SCIN,IL6ST,ITPKB,JAK2,KCND2,KIF2A,PAXBP1,HECTD2,LSS,MAP2,MBNL1,MITF,GIT1,MYO6,RTL5,NFE2L2,SLC11A2,NTRK2,NTRK3,TBC1D25,PCDH8,PCSK1,PDCD2,PDE4B,PKD1,PLCL1,PCDH18,LRP12,PSAT1,ING3,PKIA,CNTLN,SPDL1,PTPRD,PTPRO,ACSM5,RET,MORC4,SLC25A36,RIC8B,NUDT11,CCDC82,CARF,ELP2,RPL15,STK32B,RYR3,CCDC112,SBF1,SCN8A,SUPT20H,TRA2B,SGK1,FAM102A,FBXO11,FNDC3A,NLGN1,NUBPL,PREX2,PPP4R3A,BTBD3,WDR47,SLC6A11,SLC12A2,ELMO2,CPEB4,SMARCC2,RCOR3,SNAP25,USP33,PDZD2,ITPRID2,ZNF302,NKAIN2,NXT2,SYNE2,VPS13A,SYP,MTCL1,TAF9,TCEA1,ZEB1,ITGB3BP,ZMAT3,ARL10,MTMR14,TP53BP2,RGMB,TRO,TSN,RPL7L1,UBE2H,UBE3A,UGT8,XRCC4,ZNF19,KCNT2,ZNF74,EML6,SMARCAD1,CADM2,HPS4,MDH1B,GAL3ST3,NAV3,KAT6A,SMIM8,PHTF2,JMJD1C,TIGD6,RNF170,KLHDC1,FRMD6,NETO1,DPF3,GAN" MicroRNA hsa-miR-508-3p:mirSVR_lowEffct hsa-miR-508-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.45E-96 2.49E-92 6.22E-95 5.73E-94 256 1513 "RALGAPA1,ADD1,AXIN2,KIAA1211,MTA3,ZNF608,PCDH19,SPARCL1,SEMA6A,BBOX1,AMPD3,C6orf89,APAF1,EPB41L5,LINC00173,CDK13,NCOA1,RASL11B,ATP1B3,DPY19L3,DOCK11,BMPR1B,DST,FUBP1,SGCE,KALRN,PTBP2,CAMK2G,CAST,HIP1R,RUNX1T1,PRC1,MTMR7,DLGAP2,DLGAP1,CCPG1,SOCS6,CNOT8,ABCG2,CNR1,ARMC8,COL4A5,CNRIP1,PREPL,CREM,RBM39,CRHBP,HINFP,ABCG1,MROH8,LRIG1,SIPA1L1,PLXNA4,DZIP3,UBXN2A,PLCXD3,USP6NL,DOCK4,GAPVD1,TM9SF4,MATR3,KCTD8,PABPC5,ZNF804A,MFAP3L,FBXL5,WDR20,GRIN3A,NR1D2,DOCK2,DTNA,EDNRB,FCF1,FRY,PHF20L1,MBNL2,EIF4G2,COPS4,TENM1,GPHN,EYA1,TAOK3,FER,FGF12,SUCO,SYNCRIP,FLT1,NOP56,AKAP3,STAMBP,KHDRBS3,GABRG2,GALC,DISC1,SRRM4,GATM,ALDH1L1,TUBGCP4,ARFIP1,MMADHC,FREM1,PPARGC1A,TCERG1,SPIN1,RAB30,HTATSF1,DCLK2,ADGRA3,CNTRL,BVES,PSIP1,RNFT2,NCKAP1L,HLF,AGFG1,TCEAL6,HSF2,MSL1,IGF1,LRRCC1,IL6ST,JAK2,ASPRV1,PACRG,SMAD9,MAN2A2,AQP11,MATN2,MBD1,LRP1B,MEIS1,KCTD6,XRRA1,LAYN,MYO5A,MYO6,MYO9A,CNOT4,OCRL,PCDH8,PCDH9,PCSK5,PFKFB3,PIK3R1,KCTD15,FAM216A,ING3,PPARA,PPP2R2C,PPP2R5E,KANSL1,PKIA,EPDR1,HYDIN,RELN,VPS13C,BDNF-AS,TMEM260,ZSCAN32,PTPRG,NKAIN1,TUG1,ZNF844,PID1,RAP1GDS1,RASGRF2,RBBP8,RDX,REV3L,RNASEL,ROBO1,ROBO2,EPHA10,RPL15,FBXW7,SPIN3,MAP6D1,LRRK2,ABCA11P,RTN1,ZNF331,CCDC112,SALL1,ATXN2,ATXN7,SEC14L1,MRAS,SUPT20H,HSPA4L,FNDC3A,NLGN1,SEC31A,SEPHS1,CCDC88A,KIF13A,CABCOCO1,PDZRN3,PDZD2,BDP1,DOK5,SP4,ERC1,MCF2L2,NFASC,LARP4,ZSCAN29,CEP68,DIP2A,KANK1,KLHL7,NECAB1,ZC3H4,PRRC2C,VPS13A,PLCB1,DNMBP,TPCN2,TCF12,SIRT1,DICER1-AS1,AKTIP,CSMD1,PIK3R5,METTL3,NEIL2,TSC1,UBE2H,UBE3A,LINC00689,FLRT2,VLDLR,WIPF1,WRN,XPO1,XRCC4,ZIC2,ZNF711,ZNF24,AGMO,ZNF138,CELF4,FSTL5,ZNF184,ANKS1B,CADM2,SLC38A1,WNK3,DNAH10,FZD3,UBE3B,JMJD1C,RNF170,KLHDC1,FXR1,FRMD6,FAM198A" MicroRNA hsa-miR-877:mirSVR_lowEffct hsa-miR-877:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.56E-96 3.11E-92 7.76E-95 7.14E-94 258 1538 "KCNH8,ASPHD1,ACADM,ASIC1,TMEM132B,GALNT13,KIAA1211,RNF150,ESYT2,MTA3,ZNF608,KLHL13,CASKIN1,KIAA1324,ALCAM,FAM135A,BIN1,EP400,CCDC146,PARG,EPB41L5,TNRC6C,SEMA4G,MADD,CADPS,TMEM108,SLC4A4,SLC2A11,BCS1L,ZNF599,CFLAR,KSR1,GPC2,WASF1,PTBP2,SLC25A14,PRC1,ENTPD6,CDC25B,EVI5L,CACNA2D2,ASIC3,CNOT8,NGEF,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,IGDCC3,GDA,ABCG1,CS,SNCAIP,CSF1R,FAM169A,ERC2,CCDC144A,HDAC9,ZNF337,PITPNC1,RHOBTB1,SGSM2,WDR20,DMD,DNAH9,DMTF1,FAM78B,MAMLD1,DNAJB6,HEYL,TMTC1,PHF20L1,KMT5B,EIF4G2,ELN,USPL1,ENO2,RCAN2,LRRC17,DENND4A,MRPL37,ZNF461,ZMYND10,FCGRT,FECH,FGF1,FGFR1,AMOTL2,ANKFY1,SLC37A3,FAM49B,ATP6V1H,ERGIC3,KHDRBS3,SARAF,GALNT15,GABRG1,GALC,ERAP1,C15orf41,DISC1,SULT1C4,LYVE1,GLI2,AIFM3,ADGRA3,GPR12,MCHR1,TMEM121B,DIDO1,ADAMTS13,BTN2A1,AP4S1,HAS2,GABARAPL2,SYNPO,AGBL5,TCEAL6,HSPA1L,SMAP1,TJAP1,DISP2,INSM1,SLC35G1,KCNF1,KCNH2,L1CAM,LAMP2,SYTL4,PIK3AP1,MAN2A2,MARK1,LRP1B,ZNF680,TAGLN3,LAYN,MYO9A,ZNF862,FXYD7,ZC3H12B,ALDH1L2,NME4,SETD4,PAX6,PDE1C,PDE4D,GNG2,ZFYVE21,PURG,MAPKAP1,LRP12,EPB41L4B,FA2H,CCDC144B,PRKACB,MAPK4,HYDIN,MASP1,SAMD9,PIGG,PTPN13,PTPRB,PTPRD,NKAIN1,CEP97,SH3TC2,RASGRF2,ZDHHC14,DPF2,PRIMA1,TMLHE,ROBO1,YY1AP1,MAP6D1,LRRK2,MEG3,ATAT1,KCNIP3,DGLUCY,SATB1,SEC14L1,CASC3,GALNT10,COPZ1,SH3GL3,SHC4,WDR37,SLA,FAM81A,PPP4R3A,EPN2,SLC8A1,SLC12A2,NAPB,BTBD7,LGI3,IFT122,ANKRD36,INAVA,SNRPN,TMCC1,KDM4B,BDP1,KDM4C,TEX2,ZBTB43,NFASC,ITPRID2,JMJD6,ARHGEF9,SIN3B,RPGRIP1L,TCF12,NAT16,PCDHB9,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,RNF216P1,MTMR14,TMEM9,ERCC6L2,PRRT1,KAT6B,DOK6,ZNF346,TRPS1,DCBLD1,CA14,TTTY15,FLRT2,CLDND1,ZNF24,ZNF32,TRIM9,AGMO,NDRG4,CELF4,REEP1,DHX33,SLC30A4,PRTFDC1,DNALI1,SLC17A7,PCBP4,WNK3,FZD3,UBE3B,RNF170,IFT88" MicroRNA hsa-miR-4274:mirSVR_lowEffct hsa-miR-4274:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.35E-96 3.55E-92 8.84E-95 8.13E-94 247 1411 "NDRG2,GALNT16,AXIN2,AP2A2,HACE1,USP35,CARNS1,PCDH10,FAM135A,OGT,PHF12,APC,AQP6,INSYN2B,EIF4G3,ATP1B3,SLC2A11,BACH1,NRP2,SYNJ2,ARHGEF7,GYG2,CALB1,KALRN,PTBP2,CAMK2G,SPAG9,CBLN1,CLDN10,MTMR7,SLC16A4,C1orf52,SEPT7,CDC25B,LARGE1,CDO1,CCPG1,SRSF11,LHX2,RAB33A,NRXN3,FAM19A5,COL4A5,MAGED1,RCHY1,AHCTF1,FAM171B,SEC31B,CREM,CSF1,LRRC3B,CSNK1E,KIAA0040,RIMS2,HDAC9,ARHGAP32,ZNF337,MATR3,KIAA0586,MAML1,IP6K1,BRINP1,ARMCX2,SPATA2,ZBTB24,MYEF2,TMEM130,SNAP91,FAM107B,GRIN3A,RAB39B,DMD,DMPK,SLC29A4,DMTF1,DTNA,ABCC5,DNM1L,EDNRB,HIPK3,FRY,PHF20L1,AASS,PAN3,LRRC17,EPHB1,GPHN,ADGRV1,FAM198B,FDFT1,FGF13,FHL1,SEC23B,IP6K2,SYNCRIP,AGAP3,WDR83,UFM1,ATP6V1H,STAU2,MPP6,TRAF3IP2,ZNF274,IP6K3,IQGAP2,DISC1,LRRC37A6P,SESN1,PPARGC1A,CRCP,MSL3,STARD3,GPD2,STMN2,PLCD4,GSTM5,AGFG1,SHISA6,LRRCC1,LAMP2,CAMK2N2,LIMS1,HECTD2,MATN3,MBNL1,LRP1B,SRSF12,KCTD6,MIA2,MMP16,ADAM22,SAMD14,MYO9A,NFE2L2,NOVA1,NTRK2,NUCB2,OPRL1,PCSK5,PFKFB2,NLE1,PMP22,MAPKAP1,PPM1B,LRRN3,PRKACB,EPDR1,PRPSAP2,MASP1,BDNF-AS,MTMR10,ZSCAN32,PTPRD,PID1,KHDRBS2,RET,GTDC1,RGS4,SLC25A36,CCDC82,KLHDC8A,GSTCD,ZC3H14,HUNK,ZNF568,RYR3,FAM192A,SALL1,SEMA6D,SATB1,SCN8A,FAM102A,FBXO11,NUBPL,WDR37,ARHGEF40,KBTBD4,CXXC4,GKAP1,CDK5RAP2,ANKRD36,LIMCH1,USP33,FAM219A,TRERF1,MYCBP2,TEX2,ZNF423,ZC3H13,DBNDD2,ITPRID2,SSPO,STAU1,ZSCAN29,TTBK2,KANK1,NSFL1C,PRRC2C,ADAMTS17,SYT1,CAMTA1,FBXW11,SATB2,SYNE1,OBSL1,FRYL,CYB561A3,PMS2CL,SIRT1,C18orf54,AP4E1,AKTIP,NACC2,HEY1,BEX4,RASD2,DOK6,TRIO,DCBLD1,TSN,ANKRD20A2,TSC1,ZKSCAN5,UCHL1,FLRT2,USP1,TOM1L2,VLDLR,WIPF1,P2RY12,CLDND1,ATP6V0E2,CELF4,FSTL5,EML6,ZNF189,MAP3K12,SLC38A1,EVI5,ADAMTS9,TMEM178A,PDSS2,DOCK8,RTN4,RNF170,NETO2,JPH3" MicroRNA hsa-miR-653:mirSVR_highEffct hsa-miR-653:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.69E-96 4.86E-92 1.21E-94 1.11E-93 254 1494 "ADCY6,TMCC3,BRAP,PTCHD1,BEND6,INTS2,CC2D2A,MARCH4,PCDH10,FAM135A,CDC42BPA,PHF12,APC,UPRT,DDO,LGR5,LINC00173,CDK13,ZNF582,N4BP2L1,DPY19L3,LINC00847,MPDZ,JAZF1,CACNB4,CALB1,CALB2,CAMK2B,CARS,LDB2,KRIT1,SCARB1,CD38,CDH2,CLGN,C4orf33,HECTD1,FHL5,ARHGEF6,FAM149A,ABI3BP,BAG4,ZFP28,SLC35F1,CLOCK,CSF2RA,SIPA1L1,SOCS5,PDE4DIP,FAM169A,RIMS2,USP6NL,CYBB,BOC,HDAC9,ZFYVE16,LIN54,PABPC5,ZBTB24,HEPH,KIAA0319,RHOBTB1,PLPPR4,SPOCK3,DMD,HS3ST2,NR1D2,CDON,SLC25A18,EBF1,EDN1,EDNRA,EDNRB,HIPK3,MBNL2,AASS,GOLGA7,RGS17,RCAN2,EPHB1,SRRM1,DENND4A,VPS26C,RRAGB,ADGRV1,CLVS1,FAM198B,TAOK3,FCGR1A,FCGR1B,ZSCAN30,GORAB,SEC24B,SUCO,HPCAL4,IP6K2,FLT1,SMC2,STAMBP,CELF1,STAU2,SARAF,FYN,GATM,IGSF5,GGTA1P,GHR,LYVE1,RUNDC3A,SPIN1,TOX3,MAP7D2,LUZP2,GNAL,LOXL3,DIDO1,CIT,SOX21,IRAK3,PADI2,ELOVL5,SYNPO,HMGCR,HNMT,DHX35,SHISA6,ZIC5,RBPJ,FAM69A,IPO5,LMO2,MAP2,MAP4,LYPLAL1,MBNL1,ZNF680,THYN1,MYO9A,ZNF862,NCAM2,NF1,NFYA,NOVA1,CHAMP1,OPA1,OXTR,CNTN3,PCSK5,GNG2,SNX10,KCTD15,GPSM2,PLCL1,JAKMIP1,PLIN1,PCDH18,LRP12,SCHIP1,ING3,PPM1B,PPP2R2B,PPP3CC,KANSL1,PRKCB,GRAMD1C,HYDIN,DCHS2,MASP1,CNNM2,VPS13C,PIGG,BDNF-AS,ELOVL2,TMEM260,STK32A,PTPRB,PTPRD,PTPRG,PTPRO,QDPR,USP47,RAD17,FAT4,SUSD4,ZCWPW1,RFX3,RNASE1,ZNF532,SETD5,CARF,ROBO2,NEK11,ATP8B4,ADAL,ABCA11P,CLIP1,SALL1,SCN8A,CPEB3,CHD9,ANKRD6,PPP4R3A,CCDC88A,SLC12A2,ZNF334,ATF7IP,TET1,RCOR3,ANKRD36,SNRPN,TSPYL2,LMO3,ATP10B,SSTR1,SS18,ELOVL4,TTBK2,SYNE2,RPGRIP1L,SYNE1,SIRT1,ZFPM2,ITGB3BP,AP4E1,TIAM1,BHLHB9,ERCC6L2,FAM124A,ANKRD20A2,CLHC1,UBTF,WIPF1,ZNF781,ZBTB14,ZNF711,AGMO,LYPD6,ZNF138,SLC30A4,EMSY,MFF,CADM2,PRDM10,HPS4,PARP11,RTN4,UBE3B,SMIM8,PHTF2,CASC15,ADAMTSL3,JMJD1C,NHSL1,NETO1" MicroRNA hsa-miR-148a*:mirSVR_highEffct hsa-miR-148a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-95 5.80E-92 1.44E-94 1.32E-93 259 1554 "KCNH8,ACADM,CLK4,PTCHD1,INTS2,PCDH19,KCTD16,HFM1,OGT,PKP4,USP37,ARNTL,PLA2G4C,ZBTB10,EIF4G3,ATP1B3,ATP2A2,ATP2B2,ADAM23,BACH1,DST,IL33,CA12,DDR1,KALRN,SLC25A14,CLDN10,C1orf52,AP4M1,LARGE1,CHGB,PPT2,TPP1,NGEF,ABCG2,HECTD1,CNN3,FAM149A,LETMD1,AKAP5,RTTN,NCOR1,GDA,SNCAIP,CSNK1E,SOCS5,CST3,FAM169A,APPL1,UBXN2A,PHF14,PUM1,ZSCAN23,DCAF4,ARHGAP32,KATNAL2,LONRF1,MATR3,KIAA0586,PITPNC1,FBXL5,ALKBH8,SPOCK3,WDR20,USP3,DNAH9,NR1D2,DOCK2,CASP8AP2,DPP6,TOM1,WDPCP,CNNM1,FRY,FAM13A,EGFR,KMT5B,COPS4,PAN3,USPL1,TUBD1,RCAN2,ERCC2,CEP78,ZNF589,SEC24B,FGF11,FGF13,PRKAG2,UBE2E3,VTI1B,SYNCRIP,FLT1,NBEA,PDLIM5,ATP2C1,CELF1,CGREF1,STAU2,FYB1,ZMAT1,MEGF10,CHL1,GABRG2,IQGAP2,ERAP1,GDF9,ADAM28,PPARGC1A,RAB30,MSL3,PRUNE2,FUT10,STMN2,DIDO1,ATE1,FAM19A2,ZBTB49,IRAK3,RASSF8,UBE2QL1,ZHX1,FRMD5,ELOVL5,HMGCL,HMGCR,CELF5,IDH3A,LRRCC1,SCIN,LRRTM1,SLC35G1,KCND2,KCNN2,KIFC3,PAXBP1,MAP4,MBNL1,MEST,AFDN,MN1,MYO9A,NF1,CNOT4,NOVA1,SLC11A2,NRCAM,NTRK3,NUCB2,CLDN11,ETFRF1,PDPK1,CYTL1,ABCB1,PIK3C2A,ZNF655,TMEM38A,FAM216A,SDK2,PPP2R2B,PPP2R5E,RASGEF1B,CEP41,GRAMD1C,SNRK,BDNF-AS,TMEM260,PTPRD,PTPRG,RAD17,FAT4,OXR1,RBBP6,ERI2,GTDC1,RGS12,DCUN1D2,TMLHE,EXD2,CARF,GSTCD,RORB,CCDC102B,SNX22,ZC3H14,LRRK2,CLIP1,TRAPPC13,FNIP1,KIF27,SCAF8,ZFP30,FERMT1,KIF16B,CPEB3,CHD9,FNDC3A,ST6GAL1,NLGN1,ABLIM3,WDR47,CCDC88A,NAPB,BTBD7,ZFP1,RCOR3,BDP1,KDM3A,SP4,KDM4C,ERC1,SPTAN1,TROVE2,NKAIN2,KANK1,STXBP1,PRRC2C,VPS13A,PLCB1,ADGRL3,TBCEL,SATB2,CUX2,ZEB1,TRIM2,TCF12,CLASP1,NAT16,PCDHB9,FRYL,ZMAT3,RUNDC3B,TRPS1,TSN,CLHC1,SGK3,UBE3A,CCDC14,VLDLR,WIPF1,SLC47A2,TCEAL7,ZNF142,REEP1,SPIRE1,UPF3A,ZNF225,EMSY,LINC02210,PRDM10,TMEM178A,KCNAB1,FZD3,DOCK8,SMIM8,PHTF2,ADAMTSL3,NETO1,SENP7" MicroRNA hsa-miR-4252:mirSVR_lowEffct hsa-miR-4252:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.28E-95 7.17E-92 1.77E-94 1.63E-93 284 1861 "ASIC1,CLK4,ABHD6,AS3MT,FMNL2,GALNT13,ADD1,PWWP2A,KLHL13,KIAA1324,ADGRF5,ALCAM,ARHGAP20,DOC2A,FAM131A,TNRC6C,AQP6,PPP4R4,ARNTL,RGS20,CDK13,MARCH3,MARK4,ATP1A3,STX16,ATP2A2,RNF182,ADAM15,PROM1,CASTOR3,CACNA1G,C5,CA12,CACNA1B,LURAP1,CALM1,HAP1,CAMK2A,SLC25A14,SPAG9,USP2,P2RX6,DCLK1,LRRFIP1,CLGN,DIS3L,CHRNA4,NRXN3,CLTC,MAP4K4,CNR1,CNRIP1,CPS1,NCOR1,SNCAIP,CSF2RA,SEC24C,CSNK1E,SUSD5,IPCEF1,SOCS5,PDE4DIP,RASGEF1C,ERC2,PHF14,ZSCAN23,USP6NL,CCDC144A,ARHGAP32,DCAF8,TBC1D5,PABPC5,YTHDC1,B3GAT3,MFAP3L,FBXL5,C2CD2L,KLHL3,RHOBTB1,DNM1,HS3ST2,ACOT8,DRP2,RCAN1,ABCC5,TMTC1,YAF2,GOLGA7,EIF5,C8orf37,ADGRV1,PTK2B,TAOK3,FKTN,STRADA,SLC9B2,GTF2IRD2,FGF1,FGFR1,BAIAP2,TMEM164,IP6K2,FLYWCH1,EFCAB2,POMT1,ATP6V1H,ERGIC3,CELF1,FYN,ERAP1,DISC1,GCNT2,CRCP,DBF4,ADGRA3,FUT10,STON1,SPACA9,CACFD1,BTN2A1,GSTM5,BVES,AP4S1,ATOH8,UBE2QL1,MAN1B1,MIER3,HLF,ZNF491,SMAP1,IRF8,IDH3A,TJAP1,FAM69A,INPP5B,ITGAM,KCNN1,CYP27C1,STMN1,HECTD2,NCOA7,PACRG,ZFYVE27,EFHB,PPM1L,MSI1,MSR1,PTOV1,N6AMT1,RTL5,ZNF862,HNRNPM,NEK1,NPTX1,GPR137C,PCSK5,TMIE,XRN1,TMEM38A,PLCB2,TRHDE,MAPKAP1,STRN3,SDK2,PILRA,PPARA,PKIA,MAPK10,KLK6,WBP1L,WDR25,PIGG,ANKHD1,STK32A,ZSCAN2,QDPR,RAD17,CCDC40,FAM66C,FAT4,NWD1,OXR1,RASGRF1,GAL3ST4,ERI2,RGS4,RGS12,RIC8B,NUDT11,RNASEL,SETD5,EXD2,GSTCD,ROBO1,ROBO2,RORB,GLDN,TCP11L1,RMI1,SALL1,MAPK12,ATXN2,ATXN7,SEC14L1,COPZ1,FERMT1,FBXO11,SEC31A,ABLIM3,LIMS2,PKNOX2,SLC6A8,SLC6A11,RADIL,ARHGEF40,SLC9A5,GKAP1,INAVA,MBD5,SNRPN,FAM126B,MYO16,PDZD2,SOX11,GLT8D1,UHRF1BP1L,KDM4C,SPTAN1,ATP10B,ZSCAN29,SEPT8,JMJD6,TACR1,ADGRL3,ATMIN,DMXL2,ZFP90,TPCN2,PCDHB9,SLC19A3,NSD1,USP32P1,ARHGAP9,CCDC173,DICER1-AS1,ZNF106,NR2E1,CSMD1,C9orf85,WBP2,TSC1,SSBP2,RPRM,RPL7L1,GORASP1,BCL2L13,MTCH1,CCDC136,VLDLR,LAT2,RICTOR,XPO1,ZNF708,ZNF28,LYPD6,TMEM198,ZSCAN26,SPIRE1,DNALI1,GDPD5,STOX2,RNF103,SIGLEC10,TRIM16L,MPPE1,RGS7BP,DOCK8,UBE3B,KAT6A,ZDHHC20,ST8SIA2,GAN,FAM198A,JPH3" MicroRNA hsa-miR-888*:mirSVR_lowEffct hsa-miR-888*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.95E-95 1.09E-91 2.69E-94 2.48E-93 262 1594 "RALGAPA1,SYS1,KLHL32,GALNT13,ADD1,INTS2,ABCD2,ARHGAP20,PCDH10,DOC2A,ZFAT,LRCH2,SUGT1P4-STRA6LP-CCDC180,PARG,APAF1,EPB41L5,NT5C3B,SHROOM2,MADD,SPTBN4,RGS20,MARK4,NCOA1,BLM,BMPR1B,DST,ST3GAL5,SYNJ2,DDR1,THSD7A,HAP1,MTMR7,CBFA2T2,LRBA,DCLK1,CHGB,CLTC,FBXO7,ABCG2,QKI,CNR1,CNTFR,AKAP7,ARMC8,CLOCK,ENTPD4,ANKRD44,SOCS5,PLXNA4,DCAF4,MYADM,ARHGAP32,KATNAL2,ZNF337,MATR3,YTHDC1,ELMSAN1,POM121,SV2B,DLX1,RAB39B,DMD,NYAP1,SLC12A6,PDCD6IP,EDN3,HIPK3,TMTC1,APH1A,C8orf37,EPHB1,ERBB2,MRPL10,NSRP1,FAM198B,TAOK3,CEP78,FCGR3A,ZSCAN30,KAT8,FER,AMOTL2,AGAP2,ANKFY1,SMC2,UFM1,PDLIM5,STAMBP,CAMKK2,ATP2C1,CELF1,ZMAT1,CHL1,FAM120B,RAPGEF6,INPP5K,GATM,ALDH1L1,GCNT2,TUBGCP4,MMADHC,RNPS1,GLYR1,TOX3,HTATSF1,LOXL3,ATP2B1-AS1,GRB10,GRIA2,DIDO1,GRM8,FAM19A2,ADAMTS6,BACH2,ZDHHC15,FAM95B1,ZNF546,RBPJ,KNDC1,KCNJ16,KCNK3,KTN1,LIFR,LIMS1,GPR155,MAP4,MAP6,MARK1,MBD1,MBP,MEIS1,KITLG,SCAMP5,MMP16,NELL2,ALDH1L2,P2RX7,ZNF827,PDE4D,PDE1B,ENPP2,PDPK1,SLC10A4,PFKFB2,PIK3C2A,PIK3R1,ZNF655,XRN1,TRHDE,MAPKAP1,SCHIP1,SDK2,DRAM2,PPM1B,PPP2R5E,PRKAB2,RASGEF1B,MAPK10,DCHS2,WBP1L,SNRK,WDR25,MTMR10,PTPRE,PEX2,ZSCAN2,TUG1,QDPR,USP47,ZNF793,RBBP6,REV3L,FIGN,RFX3,PBRM1,RNASEL,EXD2,ROBO1,ROBO2,PCMTD2,NEK11,FBXW7,ZNF671,MCMBP,ATXN7,SCP2,GALNT10,MRAS,SHC4,AMBRA1,FHOD3,FAM81A,DHX30,KDM4D,SLC8A1,SLC11A1,KBTBD4,SMARCA4,SNCA,MBD5,KIF13A,SNRPN,SOX11,DOK5,KDM4C,TEX2,CDK19,TROVE2,MESP1,SAMSN1,SSPO,ST5,MPRIP,SEPT8,CEP68,ADHFE1,KANK1,KLHL7,ZC3H4,SYN2,TAL1,TRIM2,TCF12,SYNE1,NAT16,PUM2,TNS2,FRYL,SIK3,FAM200B,DICER1,DICER1-AS1,AP4E1,HEY1,KAT6B,PIK3R5,NPL,TSC2,CLHC1,LINC00689,FLRT2,TBC1D15,ZNF708,MICU3,ZNF28,TRIM9,AGMO,MKRN3,LYPD6,REEP1,POLR3H,ANKS1B,FTSJ1,EMSY,GDPD5,STOX2,URM1,FIP1L1,MPPE1,ST7,ADAMTSL3,AP3B2" MicroRNA hsa-miR-532-5p:mirSVR_lowEffct hsa-miR-532-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.03E-95 1.70E-91 4.17E-94 3.84E-93 271 1706 "CLK4,AS3MT,NDRG3,TMCC3,ZNF608,RTL9,HACE1,ARHGAP20,SYT13,AMPD3,ANK2,PARG,APBB2,PHYHD1,SHROOM2,IGDCC4,CDK13,STK33,ZSCAN18,SLC2A11,N4BP2L1,RIPK1,TTLL9,BBS2,BCHE,RGS9,NRP2,MTMR3,SGCE,IL33,CACNA1A,THSD7A,PTBP2,SLC25A14,NFS1,PRC1,ZNF501,CLDN10,RGN,SLC16A4,LRRFIP1,MAGI1,CACNA2D2,DIS3L,SRSF11,RAB28,FAM19A5,SRP14-AS1,MAP4K4,CNGA3,CNN3,IQCK,PCYT1B,AKAP5,SLC4A8,ABI3BP,MYRIP,CNRIP1,FAM171B,SEC31B,C2CD2,HINFP,ANKRD44,CS,RGS6,LRIG1,CSNK1E,SIPA1L1,PDE4DIP,CST3,PLXNA4,FAM169A,DZIP3,APPL1,PHF14,CTH,GREB1,CCDC144A,KIAA0408,DOCK4,RIPOR2,ZFYVE16,EARS2,ZNF337,TMEM170A,DAPK1,AIF1L,ARMCX4,PITPNC1,HEPH,TIAM2,MFAP3L,KLHL3,EXOG,MED12,NR1D2,DRP2,RCAN1,DTNA,SNX29,WDPCP,EDN3,TMTC1,FRY,SUGP2,MBNL2,IRAK4,GPHN,SRRM1,MRPL10,ETV1,SIRPB1,GMPR2,CLVS1,TBC1D16,CEP78,FECH,MED12L,GTF2IRD2,FGFR1,TMEM164,AMOTL2,SCARA3,UBE2E3,FOXF2,PCYOX1,SYNCRIP,NOP56,TMEM107,UFM1,MEGF11,SYT17,C15orf41,ACSS1,LRRC37A6P,GATM,GFER,MALT1,TOX3,TNRC6A,MSL3,CBX1,LUZP2,PCLO,CIT,AP4S1,PSIP1,DDX19B,AGBL5,USP51,LRRC75A,FAM95B1,C2orf72,INPP5B,ITGAM,KCND2,A1BG-AS1,TTYH2,STMN1,SFXN5,SYTL4,MARK1,MBD1,MBP,CHST6,TM6SF1,MMP16,NELL2,NINJ2,DNHD1,NTRK2,NUCB2,CHAMP1,LOC100128398,CLDN11,PDE1C,PDE4D,GPR173,GPR85,LRP12,POLG,TATDN3,PPP3CA,MASP1,CNNM2,WBP1L,PIGG,ELOVL2,PTN,PTPRH,ZSCAN2,ZNF615,TMEM255A,ZNF793,RDX,DPF2,RGS4,RGS12,RIC8B,C12orf49,PCMTD2,NEK11,ARMH4,GLDN,SGSM1,RTN1,CSRNP3,ATXN7,SCP2,SEC14L1,KIF27,PPM1E,FHOD3,ABLIM3,SEPHS1,SLC12A2,MBD5,CMTR2,SNRPN,TMCC1,FAM126B,BDP1,ZC4H2,CEP68,ADHFE1,TMEM150C,SYN2,ANKRD28,MTCL1,PJA1,KLHL4,TPCN2,TRIM2,SZT2,SYNE1,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,AP4E1,ARL10,ANKRD24,C9orf85,TRIO,AMACR,TRO,GORASP1,UGT8,FLRT2,ZNF709,XRCC4,CELF4,ANKS1B,DNALI1,STOX2,VPS35L,TRIM16L,HNRNPA3,PHTF2,FBXO36,ACTR3B,TIGD6,NETO1,CPNE4,SENP7" MicroRNA hsa-miR-556-5p:mirSVR_lowEffct hsa-miR-556-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.15E-95 1.76E-91 4.32E-94 3.98E-93 256 1526 "DGCR6,SYS1,TMEM132B,AXIN2,OLMALINC,KIAA1324,ALCAM,FAM131A,VAT1L,IGDCC4,CDK13,PDE8B,ASPA,SLC4A4,RNF182,N4BP2L1,DOCK11,BACH1,BBS2,BMPR1B,SYNJ2,MTMR2,C5,CALB1,VXN,SPAG9,LOC730101,CCPG1,NUMBL,CHN2,QKI,SRP14-AS1,HECTD1,MAP4K4,LY86,FHL5,ARHGEF6,PCYT1B,COL4A5,SMARCAL1,PREPL,HAPLN1,ANKRD44,SNCAIP,PHACTR3,PLXNA4,DZIP3,ERC2,UBXN2A,GREB1,KIAA0586,TMEM170A,ARMCX2,TMEM130,PLPPR4,ZNF582-AS1,GRIN3A,ACOT8,DTNA,GOLT1B,AASDH,EDN3,EDNRB,YAF2,RASA4,TENM1,SH3YL1,STRADA,ZNF589,FER,GTF2IRD2,FGF1,FGFR1,SUCO,UBE2E3,HPCAL4,SEMA4D,FLT1,ANKFY1,TRMO,PDLIM5,STAMBP,CAMKK2,KHDRBS3,ST6GALNAC3,GABBR1,HRASLS5,RAPGEF6,ZNF234,IP6K3,ERAP1,DISC1,CPLX2,GGTA1P,RUNDC3A,RNPS1,LOXL3,GNAO1,PRUNE2,ADAMTS13,GRIN2C,BVES,RABL2A,ADAMTS6,IRAK3,UBE2QL1,MIER3,SYNPO,HNMT,AGFG1,CELF5,SMAP1,RBPJ,SLC35G1,KIF5A,A1BG-AS1,STXBP5,TTYH2,LAMP2,LIFR,LIG4,MAP2,MAP4,MBP,MEIS1,KITLG,DBNL,SAMD5,MYCN,MYO7A,NEXMIF,MYT1,NFE2L2,ALDH1L2,NFYA,CNOT4,NTRK2,SETD4,IGSF11,OCRL,ZNF827,PDCD2,GNG2,NALCN,ZNF655,PRIMPOL,MBOAT7,POLR2F,PPM1B,RASGEF1B,PRKCB,MAPK3,EPDR1,MAPK10,PRPSAP2,RELN,MTMR10,ZSCAN32,PTPRB,PTPRE,PTX3,ACSM5,CEP97,ZNF793,SH3TC2,SUSD4,ENOX1,ZNF493,OXR1,RADX,ZDHHC14,MSANTD2,REV3L,MORC4,SLC25A36,RIC8B,NUDT11,RNASEL,TMLHE,GSTCD,ROBO2,PCMTD2,RPL15,SPIN3,ATP8B4,GLDN,ATAT1,AP1AR,PRCD,FNIP1,KIF27,SGK1,CPEB3,NLGN1,BTBD3,SLC12A2,BTBD7,EPC1,OGDHL,ANKRD36,SNRPN,MYO16,USP33,DOP1A,BDP1,NMNAT2,NFASC,CLASP2,TROVE2,POGZ,SS18,NEK4,SEPT8,RGL1,KANK1,NSFL1C,NECAB1,VPS13A,NUDT10,ADAMTS17,COBL,ANKRD12,ZEB1,TCF12,USP32P1,HIF3A,SIRT1,SLC44A1,TIAM1,TPM1,NPL,WBP2,DOK6,SYNPO2,TRO,STXBP4,PPIL6,RPL7L1,VLDLR,XPO1,KCNT2,REEP1,AMZ1,FTSJ1,UPF3A,SLC30A4,SLC38A1,PRDM10,GAL3ST3,URM1,EPM2A,RGS7BP,FZD3,DOCK8,RTN4,RNF170" MicroRNA hsa-miR-361-3p:mirSVR_lowEffct hsa-miR-361-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-95 2.03E-91 4.95E-94 4.56E-93 252 1480 "RALGAPA1,CLK4,ABHD6,ADD1,ADORA2A,AP2A2,DOC2A,AMT,C6orf89,MYH7B,PPFIA4,PKP4,CASK,TMEFF1,SPTBN4,ASGR1,MARK4,CCDC74A,NCOA1,ATP1A3,SLC2A11,RIPK1,TTLL9,ADAM15,ADGRB2,SYNJ2,FUBP1,JAZF1,PRMT9,GPC2,RAB29,MYRF,CA8,CACNB4,VXN,CAST,PRC1,METTL6,CD38,LRBA,ARHGEF2,TAOK2,DGCR9,TMEM184B,HOMER3,CNTFR,AKAP6,SLC4A8,COX4I1,TOGARAM2,IGDCC3,CDC42BPB,CRY2,HINFP,ANKRD44,SEC24C,CSNK1E,OSBPL3,APPL1,CYBB,KIF26A,TBC1D5,MAML1,B3GAT3,ZC3H11A,POM121,SV2B,SLC29A4,DPP6,TOM1,EDN1,EDNRA,EDNRB,ANKRD46,EIF4G1,TNK2,ELN,RASGRP2,DENND4A,ZNF549,PIPOX,MRVI1,EZH1,TBC1D16,TMEM132C,DLC1,SPSB4,FGFR1,HPCAL4,SYT3,DCTN2,EFCAB2,PDLIM5,RASL10A,STAU2,BRSK1,HRASLS5,CSDC2,GHR,NTNG2,TXNL4A,COPS8,RAB30,STARD3,ZNF638,KDM2B,POLL,GPER1,ATP2B1-AS1,AP4S1,LINGO1,RNFT2,TOX2,PADI2,MAN1B1,DDX19B,SYNPO,AGBL5,MSL1,FAM95B1,IDH3B,ZNF181,MYLK2,KIAA1755,METTL21A,KHK,LINC00634,KIT,A1BG-AS1,SYTL4,PACRG,MAPT,MEIS1,MEIS2,MGAT3,PPM1L,MMP16,MOV10,MPP2,GIT1,N6AMT1,HNRNPM,NBL1,NELL2,NFIX,DNHD1,PCBP3,SMIM11A,NTRK3,LOC100128398,PALM,PDCD2,NLGN3,TMIE,ANKRD16,TRHDE,POLR2F,FSD1,POU6F1,PPM1B,PPP3CA,KANSL1,MASP1,BCAS3,GDPD2,TMEM104,PTH1R,ELOVL2,PTK2,TMEM260,PTPRE,PTPRO,PEX2,ZSCAN2,NKAIN1,TMEM231,MARCH1,RAD17,ZNF793,SUSD4,RASGRF2,PBRM1,RNASEL,SETD5,YY1AP1,SNX22,EPHA10,TCP11L1,PTGR2,SCP2,HES6,STUM,ASAP3,SHC4,CHD9,R3HDM2,NLGN1,PPP4R3A,BTBD3,SLC6A8,LGI3,ABTB1,SMARCC2,INAVA,SNCA,SNRPN,DOP1A,ZSWIM8,KDM4C,TEX2,ZNF302,NKAIN2,NXT2,TTBK2,PHLDB1,SEPT3,SUPT5H,ARC,SYN2,ASTN2,EXOC7,SZT2,DOCK9,RNF216P1,CDH22,THRA,NR2E1,ERCC6L2,FAM124A,R3HDM1,RGMB,TRIO,AMACR,NUTM2A,HIRA,XPO1,LGI4,CFAP298,NDRG4,PCBP1-AS1,UPF3A,SLC30A3,GAL3ST3,PCBP4,HRASLS,DOCK8,GJC2,CASC15,FAM219B,FRMD6,SPATA13,JPH3" MicroRNA hsa-miR-567:mirSVR_highEffct hsa-miR-567:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.47E-95 2.50E-91 6.10E-94 5.62E-93 217 1093 "KCNH8,ABHD6,GALNT13,KIAA1211,KIAA1324,C1QTNF3,ALCAM,ABCD2,ARHGAP20,OGT,MAP4K3,APAF1,TNRC6C,PPP4R4,EIF4G3,DST,MTMR2,JAZF1,WASF1,CALB1,KALRN,CBLN1,KRIT1,LRBA,KCNAB3,TIGD7,CHN2,TAOK2,C4orf33,CNTN1,AKAP7,ARMC8,AKAP5,SLC4A8,AKAP12,ABCG1,CSF1R,OSBPL3,APPL1,UBXN2A,PHF14,PUM1,GAPVD1,ARHGAP24,EARS2,KIAA0586,TMEM170A,PITPNC1,MYEF2,GSDME,SNAP91,ZNF582-AS1,NR1D2,PDCD6IP,ABCC5,GOLT1B,EBF1,EDNRB,ANKRD46,TMTC1,MBNL2,EGR3,EIF4G2,PLEKHA1,CALCRL,VPS13B,EPB41L2,NCALD,CEP85L,MRPL37,VPS26C,NRN1,TMEM132C,DLC1,FCGR3A,FGF1,POLK,SUCO,FLT1,PSD2,JKAMP,UFM1,ZNF605,CELF1,ST6GALNAC3,STAU2,DISC1,LRRC37A6P,GATM,MSTN,PCDH17,LYVE1,COPS8,CBX1,GPR34,ATP2B1-AS1,HAS2,SMAP1,MSL1,RBPJ,INSM1,KCNJ16,CREG2,KIF2A,STXBP5,NCOA7,SMAD1,PIK3AP1,MARK1,LYPLAL1,AQP11,MBNL1,AFDN,XRRA1,ZNF92,NCAM2,NF1,DNHD1,SLC11A2,NRCAM,NTRK3,TBC1D25,OPA1,CLDN11,ETFRF1,PRTG,ENPP2,FAM98B,OLA1,DUSP26,SNX10,TRHDE,STRN3,LRP12,PSAT1,PPP2R5E,NKAIN4,GRAMD1C,GDPD1,SAMD9,VPS13C,QRICH1,PTCH1,ANKHD1,TMEM260,CCDC40,FAT4,OXR1,RFX3,NUDT11,RNASEL,TMLHE,EXD2,ROBO1,CCDC102B,RPL15,ATP8B4,TCP11L1,CLIP1,ZNF354C,CCDC112,TRAPPC13,SCN8A,FNIP1,HSPA4L,FHOD3,SEC31A,CCDC88A,BTBD7,RCOR3,USP33,SOX15,ZC3H13,CDK19,CAMTA2,LARP4,NXT2,SEPT8,KLHL7,PRRC2C,VPS13A,MTCL1,AGTPBP1,SMG6,TCEA1,TCF4,SYNE1,OBSL1,RNF175,SIK3,ITGB3BP,AP4E1,SLC44A1,ARL10,ERCC6L2,TMPO,TPM1,C9orf85,RICTOR,GUSBP1,XPO1,CFAP298,ZNF708,ZNF19,ZNF28,ZNF138,ANKS1B,ZNF225,CADM2,PRDM10,RNF103,KCNAB1,FIP1L1,PHTF2,ADAMTSL3,JMJD1C,FXR1" MicroRNA hsa-miR-4277:mirSVR_highEffct hsa-miR-4277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-95 2.56E-91 6.22E-94 5.73E-93 241 1355 "ACADM,KIAA1211,HECW2,OSBPL6,SMIM17,ABCD2,ARHGAP20,PCDH10,CDC42BPA,DPP10,CCDC146,MAP4K3,PHF12,PARG,DDO,LGR5,AQP6,SEMA4G,TMEFF1,ATP2A2,ADAM23,ADGRB3,BCL7A,MTMR2,JAZF1,CALB1,THSD7A,KALRN,CH25H,RUNX1T1,KRIT1,CD86,ARHGEF2,ZMYM4,TIGD7,CPNE6,NRXN3,CLTC,NGEF,FAM189A2,FHL5,CNTN1,LETMD1,ABI3BP,AKAP12,RNF14,ANKRD44,GDA,SOCS5,PDE4DIP,FAM169A,GAPVD1,RIPOR2,DCAF8,CENPL,PABPC5,ELMSAN1,MYEF2,TIAM2,GSDME,DDX46,SACS,RAB39B,DNM1,SLC29A4,CDON,DMTF1,DPYSL2,DTNA,KRBA2,E2F5,EBF1,WDPCP,EDNRA,CELSR3,PHF20L1,KMT5B,AASS,ASB3,EPHB1,GPHN,SRRM1,CEP85L,ZNF549,TLR7,EXTL2,KATNAL1,F5,ACSL4,FCGR1A,FER,MED12L,SUCO,MEX3B,UFM1,CGREF1,AP4B1,GAD1,MTHFD2,DISC1,IGSF5,GHR,PPARGC1A,TOX3,ADGRA3,GPD2,PRUNE2,GPR37,CNTRL,STMN2,DIDO1,FAM19A2,GSTM5,IRAK3,TOX2,ZHX1,HNMT,HSF2,HSPA1L,IL6ST,INSM1,NME9,KCND2,KIF2A,LAMP2,STMN1,ASPRV1,SMAD1,TM6SF1,LRP1B,MEIS1,MIA2,PPM1L,AFDN,ADAM22,MYCN,P2RY13,CNOT4,NOVA1,NRCAM,NTRK2,NUCB2,GNG2,PLCL1,JAKMIP1,EXOSC10,SCHIP1,ING3,EPB41L4B,DRAM2,RANBP3L,PRKAB2,MAPK9,GRAMD1C,MASP1,SNRK,PTPRD,PTPRG,STRC,SUSD4,ERI2,GTDC1,KLHL11,RIC8B,RNASEL,ZFHX4,CARF,ROBO2,RORB,RPE,RPL15,FBXW7,BAALC,NCBP3,ATXN7,SEC14L1,FNDC3A,SEC31A,NUBPL,ABLIM3,ARHGEF40,CCDC88A,ELMO2,SLC22A4,CXXC4,SNCA,KIF13A,KDM3A,GLT8D1,HECW1,ZC3H13,CDK19,SPART,ATP10B,SSTR1,SULF2,PRRC2C,SYNE2,SYT1,COBL,ATMIN,DMXL2,ZEB1,SZT2,SYNE1,SLC44A1,TIAM1,HEY1,TLR4,NR2E1,CSMD1,TP53BP2,ZNF346,TRIO,STXBP4,DCBLD1,CLHC1,RPL7L1,UBE3A,UGT8,BCL2L13,VLDLR,TBC1D15,P2RY12,WRN,XRCC4,ZNF24,CELF4,REEP1,FSTL5,SMARCAD1,EMSY,STOX2,HPS4,KCNAB1,PARP11,FZD3,SMIM8,PHTF2,MSRB3,FAM198A" MicroRNA hsa-miR-517*:mirSVR_lowEffct hsa-miR-517*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.84E-95 2.71E-91 6.57E-94 6.05E-93 249 1447 "ACADM,NCKAP5,NDRG3,GALNT16,CCDC85A,TMCC3,GALNT13,ADD1,USP31,FAHD2CP,PCDH19,AMPD2,ZFAT,CDC42BPA,DPP10,APBB2,UPRT,FAM131A,TNRC6C,TMEFF1,SPTBN4,NCOA1,NUMB,STX16,N4BP2L1,DPY19L3,ADGRB3,BCL7A,BTK,CASTOR3,CFAP410,CALM1,KALRN,CAST,SPAG9,KYAT1,MTMR7,NOG,UBE2L6,NDST3,LHX2,SRP14-AS1,MAP4K4,SLC4A8,ZFP28,RBM39,AKAP12,RIMS2,DCAF4,CCDC144A,BOC,ARHGAP32,GAPVD1,ZFYVE16,LIN54,DAPK1,HEPH,PLPPR4,WDR20,FAM107B,RAB39B,DMD,USP3,DYNC1I1,DMTF1,SLC12A6,CASP8AP2,PDCD6IP,EDN1,HIPK3,KLHL5,FRY,PHF20L1,EGFR,TENM1,PAN3,EIF1,RAB9B,ZNF549,GMPR2,MRVI1,ABCA8,SH3YL1,ZNF589,FECH,FGF1,FHL1,MEX3B,SEC23B,COQ5,STAU2,GABRA3,ZNF44,GALNT15,TRAF3IP2,GALC,IQGAP2,SIGLEC8,MTHFD2,SULT1C4,CSDC2,PPARGC1A,MALT1,MAP7D2,GPD2,FUT10,STON1,CLASRP,FAM19A2,PSIP1,ATOH8,IRAK3,RASSF8,SYNPO,C2orf72,NME9,KIT,LIG4,HECTD2,NCOA7,MAN2A2,MAP2,MBNL1,MBP,CHIC1,KITLG,SAMD5,ADAM22,MYO5A,MYT1,NBL1,NF1,NOVA1,PCBP3,OCRL,CHAMP1,OPA1,GPR137C,PAX6,PDE4D,TMIE,CCSER2,SNX10,PLIN1,SCHIP1,ING3,PPP2R5E,GRAMD1C,DIRAS2,GDPD1,TMEM260,STK32A,PTPN13,PTPRN,STRC,PPP2R3C,RAD51D,RAP1GDS1,RASGRF1,GTDC1,CCDC82,DCUN1D2,TMLHE,MRAP2,ADAL,TCP11L1,ST6GALNAC6,CLIP1,STX1B,NCBP3,DGLUCY,SARS,TNFRSF19,SEC14L1,CASC3,ZFP30,FBXO11,NLGN1,PPP4R3A,SLC6A11,SEPHS1,CCDC88A,MTERF2,BTBD7,CPEB4,CDK5RAP2,SMARCD3,MBD5,CMTR2,TMCC1,FAM126B,MYO16,UNC5B,ZC3H13,NFASC,ATP10B,THSD1,ZC4H2,NEK4,CEP68,KLHL7,PRRC2C,SYT1,TACC1,ADGRL3,KLHL4,TCF4,DMXL2,RPGRIP1L,TCF12,PCDHGB7,PUM2,PCDHA5,FRYL,SIRT1,ITGB3BP,ZNF106,ACTR6,ERCC6L2,FAM124A,KAT6B,RGMB,ZNF346,SYNPO2,SMUG1,STXBP4,PPIL6,ANKRD20A2,TSC1,ZKSCAN5,VLDLR,LAT2,RICTOR,PCDH20,ZNF23,ZNF138,ZBTB38,ANKS1B,GDPD5,ADAMTS9,HPS4,NAV3,FAM47E,EPM2A,RGS7BP,UBE3B,FBXO36,TIGD6,GAN" MicroRNA hsa-miR-128-3p:TargetScan hsa-miR-128-3p TargetScan 5.30E-95 2.96E-91 7.17E-94 6.61E-93 196 882 "ELFN2,ADCY6,ADD2,PLEKHH1,PTCHD1,MTA3,KCTD16,AK2,PITPNM2,ANK2,APBA2,PDE8B,NCOA1,RNF182,DPY19L3,DOCK11,NRP2,KSR1,DST,FUBP1,CA12,CACNA1A,PTBP2,C1orf52,DGKI,LRRFIP1,FOXN3,PLAA,CLCN3,QKI,HECTD1,IGLON5,CNN3,CNR1,ARMC8,CABP1,COL11A2,C2CD2,HAPLN1,CSF1,ERC2,CTH,HDAC4,LONRF1,ELMO1,RAB39B,NR1D2,CDON,DRP2,ARRDC4,DTNA,E2F6,PHC2,HIPK3,FEM1B,FAM13A,EGR3,PLXNC1,EIF5,RGS17,EPB41,EPB41L2,RCAN2,MTSS1L,EYA1,REEP2,MED12L,FGF14,ANKFY1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,MEGF11,GAD1,GCNT2,CSDC2,GHR,PPARGC1A,GPR75,KCNMB4,GPD2,DIDO1,GRIN2D,PTPRT,KAT7,MAP4K5,FAM222A,MIER3,HNF4G,AGFG1,MSL1,IGF1,INSM1,METTL21A,KCNN3,KPNA5,LIFR,MSANTD3-TMEFF1,NCOA7,LSAMP,MAN2A2,MATN3,CHIC1,MEIS2,KITLG,MN1,MPP2,MSI1,MXI1,MYT1,NF1,NFE2L2,ALDH1L2,NOVA1,NPTX1,NPTX2,OPA1,PAX6,PCDH9,CDK18,PDE3A,PDE1B,PDPK1,PIK3C2A,PIK3R1,RASGEF1B,PKIA,MAPK10,DIRAS2,RELN,CNNM2,PTPRB,RAD51D,FAM184A,RET,FIGN,RFX3,KLHDC8A,ALG9,CYB561D1,ROBO1,RORB,FBXW7,HUNK,RXRA,FAM192A,CASC3,FAM102A,PPM1E,ARX,CPEB3,CCDC92,CCDC88A,CPEB4,RCOR3,MBD5,FAM126B,KDM3A,PEG10,NFASC,ATP10B,CLSTN2,POGZ,LARP4,NXT2,ELOVL4,MCF2L,PDLIM2,SATB2,RPGRIP1L,NSD1,CRTC1,GPRIN3,FRYL,NACC2,CBX5,RASD2,FAM155A,GORASP1,PLEKHH2,BCL2L13,KCNK12,MICU3,DPYSL5,NAV3,KCNAB1,FZD3,MARCH8,KAT6A,JMJD1C,ADAMTS10,NETO2,NETO1,RNF146" MicroRNA hsa-miR-500:mirSVR_lowEffct hsa-miR-500:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.77E-95 3.79E-91 9.15E-94 8.42E-93 286 1899 "SYN3,METAP1D,TMEM132B,ADCY6,ADD1,AP2A2,INTS2,MTUS1,HACE1,OSBPL8,CC2D2A,ZNF578,ADGRF5,SEMA6A,CEP126,ZNF687,LCORL,PHYHD1,PPFIA3,SFMBT2,PPP4R4,PDE8B,CHID1,ZNF583,TTLL9,BCHE,RGS9,NRP2,DST,BTK,RAB29,CAMK2B,VXN,CAST,LDB2,CCNH,USP6,LRBA,LARGE1,MAGI1,NOG,CHN2,MS4A7,B4GALT6,NRXN3,CLCN3,TPP1,FAM189A2,QKI,CNTN1,COL4A5,COL9A1,AKAP5,ABI3BP,RCHY1,ZNF521,IGDCC3,CPS1,SEC31B,CREM,HAPLN1,CLIP3,ABCG1,SNCAIP,ARHGEF10,SUSD5,FAM169A,ERC2,RUBCN,USP6NL,CCDC144A,KATNAL2,DCAF8,ZNF337,KCTD8,MAML1,DGKB,TMEM170A,SCRN1,IP6K1,DNAL1,YTHDC1,ZBTB24,FBXL5,KIAA0753,KIAA0319,SNAP91,SPOCK3,DLX1,DMD,DPYSL2,DNAJB6,DNM1L,EDNRB,TMTC1,PHF20L1,MBNL2,EIF5,CALCRL,PAN3,USPL1,TUBD1,EPHB1,ENPP6,CEP85L,ETV1,ANKMY1,ARMCX1,RACK1,FKTN,UBE2E3,FOLH1,SMC2,FAM49B,CAMKK2,ERGIC3,CELF1,GABRG1,GAD1,ALDH1L1,TUBGCP4,DBF4,GLI2,TNRC6A,MSL3,ZNF638,KCNMB4,FUT10,GRIA2,CIT,FAM19A2,RNF165,GSTT2,PSIP1,RASSF8,ELOVL5,C9orf129,CPT1C,LRRC25,ZIC5,LRRCC1,ITPKB,JAK2,KCND2,KCNN1,STXBP5,KTN1,LAMP2,HECTD2,NCOA7,MAP2,MAPT,EFHB,MEST,AFDN,MMP16,ADAM22,MSR1,N6AMT1,MYO7A,P2RY13,NF1,DNHD1,SLC11A2,SMIM11A,NTRK2,OCRL,ZNF713,GLIPR1L2,PCDH9,PCSK5,SERPINI1,ZNF655,KCTD15,PLCD1,SMIM7,MTRF1L,DRAM2,POU6F1,PPM1B,PPP2R2C,RANBP3L,CEP41,SNRK,PTCH1,BDNF-AS,SPDL1,TMEM260,PTPRB,PTPRD,PTPRG,TUG1,USP47,SH3TC2,ENOX1,ZNF493,RASGRF2,MSANTD2,GAL3ST4,GTDC1,RGS4,RGS12,ZFHX4,SNX22,ARMH4,ZNF671,ATP8B4,RPS20,RMI1,SEMA6D,FNIP1,FOXRED1,SH3GL3,SHC4,CHD9,FBXO11,NLGN1,SEC31A,DZIP1,SEPHS1,CCDC88A,SLC11A1,SLC12A2,SLC14A1,GKAP1,ANKRD36,INAVA,KIF13A,ZNF415,SNRPN,SOX11,ZSWIM8,HECW1,MYCBP2,PEG10,SPTAN1,CDK19,TSPYL2,ATP10B,NKAIN2,CEP68,KANK1,SEPT3,STXBP1,ZC3H4,ADAMTS17,SYN2,TACC1,TACR1,MTCL1,FAM208A,TBCEL,IQCE,ZEB1,SIRT1,DICER1-AS1,C18orf54,TK2,ACTR6,ANKRD24,KAT6B,WBP2,RUNDC3B,STXBP4,PPIL6,TSN,ANKRD20A2,TUBB1,RPL7L1,LINC00689,BCL2L13,VAV1,WNT7A,MICU3,MKRN3,LYPD6,DNALI1,FAM47E,WNK2,RGS7BP,FAM13C,DOCK8,KAT6A,HNRNPA3,KLHDC1,FRMD6" MicroRNA hsa-miR-218:mirSVR_highEffct hsa-miR-218:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.64E-95 5.39E-91 1.30E-93 1.20E-92 234 1281 "RALGAPA1,ACTN1,ADCY6,GALNT13,BEND6,SLC24A4,NME5,KIAA1324,SYT13,LCORL,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,UPRT,CDK10,RGS20,ASPA,CCDC74A,NUMB,INSYN2B,ZNF583,BACH1,ADGRB3,SEC11C,BCHE,PROM1,CALM1,KALRN,SLC25A14,VXN,CCNH,L3MBTL4,SOCS6,NRXN3,ABCG2,FHL5,ARMC8,SUMF2,ABI3BP,ZFP28,SLC35F1,FAM171B,PREPL,CRHBP,ANKRD44,TRIM69,CRYM,SNCAIP,RGS6,LRIG1,ERC2,PUM1,ZSCAN23,RIPOR2,KCTD8,AIF1L,DBN1,ELMO1,RHOBTB1,PLPPR4,SACS,SV2B,SPOCK3,HS3ST2,NR1D2,ARRDC4,GOLT1B,EBF1,CNNM1,KLHL5,FAM13A,EGFR,MBNL2,KMT5B,GOLGA7,CALCRL,PAN3,LRRC17,GPHN,MRVI1,NSRP1,FAM198B,ZNF461,KAT8,GORAB,FER,MED12L,FGF12,POLK,SCARA3,FOXF2,FLNC,NELFCD,C2orf88,TMEM107,APOPT1,ZNF605,KHDRBS3,STAU2,OGA,GABRB3,TRAF3IP2,ERAP1,TUBA8,MALT1,LYVE1,COPS8,GLI2,RAB30,TOX3,ZNF638,GNAO1,PCLO,GRIA2,ZBTB49,SOX21,MIER3,HLF,ELOVL5,HNMT,C9orf129,ZDHHC15,SHISA6,IRF8,ZNF678,KIF2A,KIT,STMN1,HECTD2,NCOA7,MBNL1,LRP1B,MEF2C,MEIS2,MITF,MXI1,NELL2,PCDH8,PCDH9,SERPINI1,PIK3C2A,PIK3R1,TRHDE,MINDY2,CCDC144B,PPP2R2C,PPP2R5E,KANSL1,CEP41,MAPK9,HYDIN,MASP1,RELN,VPS13C,ELOVL2,ZSCAN32,RASGRF2,SLC25A36,ZFHX4,TMLHE,GSTCD,ROBO1,ROBO2,PCMTD2,RPE,ATP8B4,KCNIP3,ATXN2,SCN2B,SCN8A,SUPT20H,KIF16B,SHC4,FNDC3A,FHOD3,ABLIM3,SLA,FAM81A,PPP4R3A,BTBD3,WDR47,SLC6A11,SLC8A1,CCDC88A,SLC12A2,CPEB4,COA1,IFT122,MYO16,KDM4C,LMO3,NKAIN2,ERBIN,DIP2A,STXBP1,NECAB1,JMJD6,VPS13A,NUDT10,TMEM150C,SYN2,SYPL1,SATB2,TCF12,SYNE1,DOCK9,PCDHA5,CHST8,ACTR6,TMPO,RIMBP2,AMACR,STXBP4,DCBLD1,SGK3,UBE2H,UCHL1,UGT8,RBFOX3,TRIM9,CELF4,SPIRE1,UPF3A,CADM2,DNALI1,GDPD5,RNF103,NAV3,RTN4,NHSL1,DPF3,GAN" MicroRNA hsa-miR-597:mirSVR_lowEffct hsa-miR-597:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.84E-95 5.51E-91 1.32E-93 1.22E-92 248 1440 "AS3MT,SYS1,PSMG3-AS1,ADD1,FZD9,BEND6,CC2D2A,ARHGAP20,SYT13,SUGT1P4-STRA6LP-CCDC180,APBB2,MAGEE2,VAT1L,PPFIA3,SHROOM2,SLC4A4,DPY19L3,MYOM1,ADGRB3,LINC00847,KSR1,DST,JAZF1,MYRF,CA8,DDR1,CACNB4,KALRN,HAP1,CAMK2B,PRC1,KYAT1,CBFA2T2,SCARB1,AP4M1,SEPT7,CDH2,CLGN,SRSF11,CNOT8,NDST3,CLTC,VAX2,MAP4K4,AKAP6,COL4A5,ABI3BP,ZNF521,CNRIP1,C2CD2,ANKRD44,RGS6,SEC24C,ARHGEF10,SUSD5,CNTNAP2,KIAA0040,GREB1,RIMS2,DCAF4,USP6NL,CCDC144A,CYBB,KIAA0408,GAPVD1,TCAF1,DCAF8,ZFYVE16,EARS2,LONRF1,BRINP1,AIF1L,YTHDC1,DGCR5,SV2B,GRIN3A,CPEB2,PDCD6IP,MAMLD1,DNM1L,TNK2,STARD3NL,EMX2,ENO2,ERCC2,ZNF549,ETV1,F8,TAOK3,PRKAG2,FOXF2,PCYOX1,SYNCRIP,FOXO3,EVL,EFCAB2,WDR83,SARAF,ZNF234,ZNF559,DISC1,SULT1C4,MSTN,PPARGC1A,LYVE1,TXNL4A,COPS8,TOX3,GNG4,GPT2,ADGRA3,PRUNE2,GRIN2D,BTN2A1,BVES,PSIP1,TOX2,MAN1B1,ELOVL5,ZDHHC15,TCEAL6,FAM95B1,INPP5B,A1BG-AS1,MAN2A2,MAP4,MBP,LRP1B,MEIS2,MMP16,ZNF680,PTOV1,MT1M,RTL5,ZC3H12B,NF1,PFKFB4,OLA1,ZNF655,KCTD15,PLXNB1,PDZRN4,MAPKAP1,LRP12,SCHIP1,ING3,RETREG2,PPARA,PPM1B,LRRN3,RASGEF1B,PRKACB,KLK6,BCAS3,VPS13C,DEF8,GDPD2,SNRK,QRICH1,CNTLN,PTCH1,BDNF-AS,PTN,TMEM260,PTPRG,PTPRH,PTPRO,PEX2,MARCH1,PID1,USP47,ENOX1,ZDHHC14,ZMAT4,RET,ERI2,GTDC1,RFX3,RIC8B,LGI2,CCDC82,PNMA8A,ATP8B4,HUNK,KCNIP1,ZNF331,FAM192A,SCP2,FOXRED1,SH3GL3,FERMT1,CHD9,SEC31A,NUBPL,SLA,KANSL3,ANKRD36,SNCA,KIF13A,FAIM2,FAM126B,DOP1A,SP2,ZC3H13,CDK19,TSPYL2,ZC4H2,LARP4,NXT2,STAU1,KANK1,SUPT5H,ARHGEF9,PLCB1,SYT1,ANKRD12,RPGRIP1L,SZT2,DOCK9,SLC19A3,PUM2,ARL10,TIAM1,MTMR14,ACTR6,CSMD1,RGMB,ZNF346,TSC1,SGK3,VLDLR,WIPF1,CLDND1,SLC47A2,KCNT2,LYPD6,TCEAL7,ZNF138,CELF4,LINC02210,HPS4,FAM13C,ST7,FAM219B,MSRB3,NHSL1,FXR1,PRRT4" MicroRNA hsa-miR-576-3p:mirSVR_lowEffct hsa-miR-576-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-94 5.79E-91 1.39E-93 1.28E-92 292 1979 "KCNH8,CLK4,SYS1,GALNT16,PSMG3-AS1,CCDC85A,RNF157,PLEKHH1,ADORA2A,UNC5A,BEND6,HECW2,HACE1,CC2D2A,C1QTNF3,PCDH10,GPRASP2,FGD2,C6orf89,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,MAGEE2,TNRC6C,IGDCC4,RGS20,ARRB2,TMEM108,SLC4A4,SLC2A11,ADAM15,BACH1,BBS2,MPDZ,SEC11C,BID,BMPR1B,CASTOR3,SGCE,CA12,CALB1,PTBP2,CAST,PRC1,USP6,CBFA2T2,C1orf52,DGKI,ARHGEF2,ZMYM4,DLGAP1,CACNA2D2,ASIC3,CHN2,EPS15L1,NRXN3,QKI,MAP4K4,ARHGEF6,AKAP6,RCHY1,BAG4,IGDCC3,SLC35F1,CDC42BPB,CREM,NCOR1,ABCG1,RGS6,CSNK1G3,VAC14-AS1,CNTNAP2,PLXNA4,FAM169A,DZIP3,PHF14,ZSCAN23,USP6NL,CCDC144A,KIAA0408,HDAC9,EARS2,ZNF337,DGKG,TMEM170A,ARMCX4,HEPH,FBXL5,TMEM130,RHOBTB1,SNAP91,SACS,WDR20,FAM107B,CHRDL1,CDON,SLC12A6,DPP6,PDCD6IP,DTNA,SNX29,EDNRA,EDNRB,CNNM1,SEMA3D,SUGP2,COPS4,PCOLCE2,TMEM35A,EPB41,EPB41L2,EPHB1,GPHN,STX2,ETV1,KATNAL1,F8,FAM198B,GTF2IRD2,BAIAP2,FHL1,POLK,SCARA3,MEX3B,HPCAL4,PSD2,NELFCD,AKAP3,SMC2,PDLIM5,ERGIC3,CGREF1,ZNF274,INPP5K,GATM,NEU3,MSTN,ARFIP1,MMADHC,GFRA2,GGT7,HPGDS,GLI2,MSL3,CBX1,KDM2B,LUZP2,LILRB4,GPR12,STMN2,BTN2A1,PTPRT,BVES,AP4S1,LINGO1,RNFT2,GUCY1B1,ATOH8,ARHGAP36,HMGCR,FAM95B1,DISP2,ITPKB,SLC35G1,KCNJ5,KIF5A,SYTL4,NCOA7,MAP4,MATN2,CHIC1,MEF2C,KITLG,MXI1,NCAM2,NEK1,NF1,ALDH1L2,NTRK2,NTRK3,NUCB2,GPR85,ZDHHC8,PIK3C2A,CCSER2,SNX10,GPSM2,FXYD1,PSAT1,SCHIP1,PPM1B,RANBP3L,PRKACB,CEP41,PRKCB,MAPK10,HYDIN,RELN,TMEM260,PTPRE,PTPRH,PTPRO,C1orf109,SH3TC2,RAP1GDS1,ZNF493,RBBP6,RDX,ERI2,GTDC1,UBR7,RGS3,RGS12,PRIMA1,TMLHE,KLHDC8A,ALG9,CARF,ROBO1,ROBO2,PGBD4,GLDN,SGSM1,ATAT1,SATB1,ATXN2,SCN8A,SCP2,TNFRSF19,ZFP30,AMBRA1,FBXO11,SLC8A1,SNRPN,FNBP1,DOK5,NMNAT2,PEG10,ZC3H13,CDK19,ZBTB43,ITPRID2,KANK1,SULF2,SYNE2,DNAJC9,SYN1,MTCL1,MLST8,KIAA1107,IQCE,ZFP90,CUX2,NSD1,FRYL,DICER1-AS1,SLC44A1,TK2,TMPO,FAM124A,R3HDM1,TSN,ZKSCAN5,TUBB1,UBE3A,ZNF709,VIPR2,WIPF1,LAT2,ZBTB14,ZNF708,LYPD6,TCEAL7,TMEM198,EML6,FTSJ1,SMARCAD1,DHX33,EMSY,SLC38A1,STOX2,GAL3ST3,SLC17A7,KCNAB1,FAM47E,ST7,HNRNPA3,PHTF2,NETO1,CPNE4,SPATA13" MicroRNA hsa-miR-1245:mirSVR_lowEffct hsa-miR-1245:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-94 7.62E-91 1.82E-93 1.68E-92 244 1396 "RALGAPA1,ADCY6,RNF150,INTS2,WDR35,AK2,HFM1,SEMA6A,ALCAM,MAP4K3,PARG,APAF1,UPRT,ARSE,DPY19L3,ADAM23,ADAM15,LINC00847,NRP2,CFLAR,BMPR1B,ARHGEF7,FUBP1,CACNA1B,CACNB4,CALM1,PTBP2,CAPN3,CH25H,METTL6,CD86,ZBED1,CCPG1,NUMBL,SRSF11,B4GALT6,RAB33A,NRXN3,CLCN3,NGEF,FAM189A2,SRP14-AS1,FHL5,CNR1,PCYT1B,FAM149A,ZNF521,CREM,CRMP1,NCOR1,GDA,ABCG1,SNCAIP,SEC24C,OSBPL3,CNTNAP2,FAM169A,SLITRK5,UBXN2A,PHF14,GREB1,CCDC144A,HDAC9,ARHGAP24,LONRF1,TBC1D5,DGKB,PABPC5,GIT2,MYEF2,DDX46,SNAP91,SPOCK3,KIF19,SEC16A,DMPK,FAM78B,DNM1L,EDNRB,SEMA3D,ASB3,ELN,USPL1,ENPP6,SLC43A2,EYA1,NSRP1,FCGR1A,CHST15,ZSCAN30,FDFT1,FECH,FER,GTF2IRD2,FGF1,FGF11,FGFR1,PRKAG2,MEX3B,TMEM107,USP21,CAMKK2,CGREF1,STAU2,NEURL4,MEGF10,FAM120B,B4GALNT1,IQGAP2,ERAP1,PCDH17,RUNDC3A,CRCP,TOX3,FERMT2,LNX1,GPD1,STON1,CNTRL,LINGO1,GUCY1B1,BACH2,HMGCL,AGBL5,HNMT,ZNF546,FAM69A,KCNB1,KLHL23,CREG2,LMO2,HECTD2,MBNL1,CHIC1,MEIS2,MMP16,MYCN,NEXMIF,ZC3H12B,CCDC13,NOVA1,NPTX1,SLC11A2,CNTN3,PAX6,PCDH9,PCSK5,GNG2,NLGN3,SNX10,ZNF426,MTRF1L,PMP22,STRN3,PSAT1,PPP2R2C,PPP2R5E,MAPK4,MAPK9,MASP1,CNNM2,CNTLN,MTMR10,PTN,EML5,PTPRH,ACSM5,USP47,FAT4,RASGRF1,CARF,ROBO1,MCMBP,GLDN,ADAL,HSD11B1L,NCBP3,ZNF331,SALL1,SCN8A,NLGN1,ANKRD6,SEPHS1,TET1,GKAP1,SMARCA4,RCOR3,LIMCH1,SNRPN,TMCC1,FAM126B,KDM4B,ZSWIM8,SPP1,PEG10,ATP10B,CLASP2,POGZ,SSTR1,NXT2,STX1A,NUDT10,PLCB1,SYN2,DMXL2,SATB2,ZEB1,SYNE1,PUM2,PCDHA1,FRYL,DICER1,SIRT1,DICER1-AS1,ZFPM2,ARL10,MTMR14,TLR4,LRRC8A,FAM124A,R3HDM1,PIK3R5,SYNPO2,CA14,SSBP2,UBE3A,BCL2L13,XPO1,ZBTB14,EMSY,STOX2,PRDM8,VPS35L,SLC17A7,FAM47E,PARP11,ST7,UBE3B,PHTF2,TIGD6,NETO2,SOCS4,SPATA13,JPH3" MicroRNA hsa-miR-374a*:mirSVR_highEffct hsa-miR-374a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.62E-94 9.08E-91 2.17E-93 2.00E-92 256 1537 "KCNH8,CLK4,ADCY8,AXIN2,PLEKHH1,BEND6,MTUS1,WDR35,ZNF578,SPARCL1,SEMA6A,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,OGT,DPP10,LRCH2,APC,BCAS1,PPP4R4,CDK13,ZBTB10,ZNF599,BMP7,DST,NAE1,WASF1,CACNA1B,KALRN,LDB2,KRIT1,C1orf52,LRBA,MAGI1,CFL2,CNOT8,RAB28,PLAA,CNR1,ARMC8,COL4A5,ABI3BP,ZFP28,SLC35F1,CLOCK,PREPL,CS,SNCAIP,LRIG1,LRRC3B,CSNK1G3,SLITRK5,UBXN2A,HDAC9,ZFYVE16,LIN54,IST1,DAPK1,PABPC5,JAKMIP2,ZNF804A,MYEF2,LYPD1,DDX46,ALKBH8,PLPPR4,MTX3,CPEB2,DPP6,DPYSL2,E2F6,EDIL3,EDNRB,KLHL5,FSD1L,OPTN,PHF20L1,MBNL2,KCTD3,PAN3,COQ7,RCAN2,EPHB1,CDKL3,RRAGB,ADGRV1,ABCA8,ACSL4,CEP78,FLT1,HVCN1,STAMBP,AP4B1,OGA,GABRG2,IQGAP2,SULT1C4,FREM1,PPARGC1A,HPGDS,SPIN1,TOX3,ZNF638,MAP7D2,LILRB4,PCLO,FAM19A2,GUCY1B1,HAS2,ZHX1,MIER3,VSIG4,HMGCR,RBPJ,LRRCC1,KCND2,KLHL23,STXBP5,L1CAM,HECTD2,MAP2,MARK1,MATN2,MATN3,MBNL1,MEIS1,KCTD6,XRRA1,MMP16,LYRM9,MYO6,NELL2,NF1,NOVA1,DNHD1,NRCAM,TBC1D25,OGG1,P2RX7,PAX6,PDCD2,PDE4B,PDE4D,GPR85,NALCN,ZNF655,PCDH18,MTRF1L,ANKRD16,PMP22,EPB41L4B,DRAM2,PPM1B,PPP2R5E,PKIA,HYDIN,SAMD9,WBP1L,TMEM260,STK32A,ZSCAN32,PTPRG,PTPRO,PPP2R3C,TMEM255A,OXR1,KHDRBS2,ZMAT4,ERI2,GTDC1,RIC8B,DCUN1D2,TMLHE,ELP2,ATP8B4,LRRK2,RPS20,ATAT1,ZNF354C,TRAPPC13,SATB1,SMPD3,SCAF8,SGK1,NLGN1,SEC31A,DHX30,FAM214B,CCDC88A,BTBD7,TET1,SMARCA4,SNAP25,SNCA,MBD5,ZNF415,MYO16,BDP1,FNBP1,KDM4C,PBLD,SAMSN1,CEP68,RGL1,KLHL7,PLCB1,SYT1,COBL,AGTPBP1,TBCEL,SIN3B,ZEB1,PCDHGB7,CLASP1,SYNE1,PCDHB4,PUM2,USP32P1,GPRIN3,FRYL,ZFPM2,ITGB3BP,ASXL3,TMPO,BEX4,CSMD1,TP53BP1,TPM1,PLEKHH2,CCDC14,WNT7A,RICTOR,GUSBP1,XRCC4,PCDH20,MICU3,CRB2,ZBTB38,EML6,ANKS1B,ZFAND5,MAP3K12,CADM2,SIGLEC10,MDH1B,NAV3,FZD3,DOCK8,KAT6A,SMIM8,FBXO36,NHSL1,SNX14,SOCS4" MicroRNA hsa-miR-1294:mirSVR_lowEffct hsa-miR-1294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.05E-94 1.14E-90 2.72E-93 2.51E-92 268 1683 "DGCR6,ASIC1,GALNT16,CCDC85A,TMCC3,ADD2,USP31,UNC5A,RTL9,KIAA1324,MAP4K3,PHF12,BCAS1,PPFIA3,SHROOM2,AQP6,SFMBT2,SEMA4G,CDK13,SLC4A4,ZNF583,ADGRB3,BCHE,CFLAR,SYNJ2,CA12,CALM1,VXN,KYAT1,CCK,CD38,ENTPD6,LRRFIP1,LARGE1,CFL2,SOCS6,NDST3,C7orf61,RAB33A,ABCG2,QKI,COL11A2,AHCTF1,CNRIP1,ZNF385A,CREM,TRIM69,CSF1,RGS6,LRIG1,CSNK1E,IPCEF1,VCAN,KIAA0040,APPL1,UBXN2A,RIMS2,DCAF4,FAM131B,KIAA0408,BOC,ZBTB24,TMEM130,RHOBTB1,WDR20,EXOG,RAB39B,CPEB2,RCAN1,E2F5,EBF1,ANKRD46,HEYL,FAM13A,PHF20L1,SUGP2,EGFR,EGR3,ASB3,PLEKHA1,C3orf18,EMX2,MTSS1L,EPHB1,EYA1,GMPR2,MRVI1,DLC1,CHST15,FCGRT,ZNF589,SLC9B2,GTF2IRD2,FGF12,MEX3B,UFM1,PDLIM5,USP21,ATP2C1,ERGIC3,CGREF1,MSANTD4,HHIPL1,DOT1L,TVP23A,CHL1,GABRG2,GAD1,IQGAP2,SIGLEC8,MTHFD2,SEPT9,GATM,IGSF5,SULT1C4,GGT7,MSL3,STARD3,POLL,LNX1,PRUNE2,FUT10,GPER1,TMEM121B,PCLO,GRB10,SPACA9,PRDM5,ZNF496,RNF165,ADAMTS6,FAM222A,RASSF8,NXPH3,ATXN2L,ZDHHC15,HSF2,LRRC75A,FAM95B1,LRRC25,SCIN,SLC35G1,CLEC18A,LYPLAL1,CHIC1,MEIS2,PPM1L,AFDN,MN1,GIT1,COMMD5,ZNF92,MYCN,ALDH1L2,NTRK2,PCSK1,PDE1C,SLC10A4,CCSER2,FAM216A,PLCB2,SLC25A23,MTRF1L,PURG,TRHDE,PILRA,PPP1R1A,TATDN3,PPP2R2B,MAPK9,GDPD1,PIGG,CNTLN,NCR3LG1,MTMR10,TMEM260,STK32A,PTPRB,PTPRD,PTPRO,PPP2R3C,SLC25A48,OXR1,ZDHHC14,RGS12,RIC8B,CCDC82,SETD5,ARMC5,CARF,CYB561D1,CCDC25,RPL15,SPIN3,GLDN,PTGR2,FAM161B,MEG3,CLIP1,TRAPPC13,ATXN2,ATXN7,SCN2B,GALNT10,COPZ1,ZFP30,ARX,CPEB3,HKDC1,AMBRA1,FNDC3A,SEC31A,EPN2,CCDC88A,SLC11A1,ATF7IP,MAPKBP1,SNCA,SNRPN,MYO16,DOP1A,SOX15,KDM3A,SP2,GLT8D1,KDM4C,UNC5B,ZC3H13,NEK4,SEPT8,ANKRD28,CAMTA1,ADGRL3,TBCEL,SIN3B,SATB2,CUX2,ZEB1,TPCN2,SYNE1,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,ENHO,WBP2,DOK6,ZNF346,TRIO,DCBLD1,CLEC2L,ZNF781,CLDND1,EML6,ZNF225,EMSY,PRTFDC1,TMEM178A,FAM47E,RGS7BP,JMJD1C,RNF170,KLHDC1" MicroRNA hsa-miR-512-5p:mirSVR_lowEffct hsa-miR-512-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-94 1.17E-90 2.78E-93 2.56E-92 274 1757 "CLK4,NDRG3,ADORA2A,PWWP2A,ESYT2,MTA3,PCDH19,WDR35,TXNDC16,CC2D2A,ZNF578,SEMA6A,SPOP,PCDH10,FAM135A,SYT13,FGD2,C6orf89,PHF12,MAGEE2,RASL11B,ATP6V0A1,BACH1,BARD1,LINC00847,SYNJ2,ARHGEF7,LURAP1,KALRN,VXN,CAST,HIP1R,ISPD,KYAT1,CDC25B,MAGI1,DLGAP2,MS4A7,NDST3,PPT2,QKI,AKAP7,LETMD1,ABI3BP,SMARCAL1,SEC31B,PREPL,ANKRD44,SNCAIP,LRRC3B,CSNK1G3,PDE4DIP,CNTNAP2,CST3,PHF14,CTH,DCAF4,USP6NL,CYBB,GPRASP1,ARHGAP32,GAPVD1,ARHGAP24,IST1,IP6K1,ARMCX4,PITPNC1,MYEF2,ZC3H11A,GSDME,DDX46,TMCC2,DMD,CDON,SLC12A6,ECM2,MAMLD1,EDN1,CNNM1,APH1A,MRO,TENM1,EMX2,VPS13B,LRRC17,NCALD,MRPL10,EZH1,TUBB3,RACK1,FCGR1A,FGF12,FGFR1,UBE2E3,HPCAL4,FOXF2,IP6K2,SEMA4D,NELFCD,NBEA,POMT1,ZNF605,DOT1L,OGA,GABBR1,HRASLS5,RAPGEF6,IP6K3,GATM,NFU1,PCDH17,PPARGC1A,LYVE1,DHRS4,BRD8,ZNF276,GLUL,GNG4,ADGRA3,GPD2,PRUNE2,GRIN2C,GRM2,LINC01089,ZBTB49,RABL2A,SOX21,GABARAPL2,SYNPO,HMGCL,HNMT,INSM1,KCNN1,KCNN3,KIF5A,A1BG-AS1,CYP27C1,LSS,ZFYVE27,MAP2,MBD1,MEIS1,MEST,SCAMP5,MID1,MN1,ZNF680,MSI1,ADAM22,MX1,MXI1,NEXMIF,ZNF862,HNRNPM,SFR1,NEK1,NFIX,NFYA,DNHD1,NUCB2,ZNF713,GLIPR1L2,CNTN3,PCDH9,PCSK5,ENPP2,PFKFB2,SEMA5B,PIK3R1,FAM216A,FXYD1,SMIM7,EPB41L4B,RASGEF1B,GRAMD1C,HYDIN,PRPH,ANKHD1,PTPRO,TRIM68,RET,ZDHHC4,RGS4,RNASEL,ALG9,GSTCD,YY1AP1,ELP2,PCMTD2,MRAP2,NEK11,KIAA0895L,MCMBP,STK32B,RPS20,ZNF331,AP1AR,SMPD3,PPM1E,FUZ,SHC4,FBXO11,R3HDM2,WDR37,SLC6A8,KDM4D,SLC8A1,ARHGEF40,SLC12A2,SMARCD3,RCOR3,INAVA,SNAP25,SNRPN,TMCC1,FAM126B,DOP1A,ZSWIM8,IZUMO4,MYCBP2,ERC1,ZNF423,SPTAN1,MCF2L2,SPART,LMO3,ZNF302,ZC4H2,APOM,CEP68,CAMTA1,TAL1,TCF4,CLASP1,DNAH7,ARL10,BHLHB9,BEX4,TNS1,TPM1,C9orf85,METTL3,ANKRD20A2,CLHC1,BCL2L13,MTCH1,CCDC136,CCDC14,WIPF1,RICTOR,GUSBP1,XRCC4,NDRG4,CRB2,TCEAL7,EML6,ANKS1B,SPIRE1,ZFAND5,UPF3A,INTS3,SLC30A4,STOX2,HPS4,VPS35L,ITM2C,PARP11,SMIM8,HNRNPA3,ST8SIA2,LAS1L,PRRT4,SENP7,JPH3" MicroRNA hsa-miR-143*:mirSVR_lowEffct hsa-miR-143*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.65E-94 1.48E-90 3.51E-93 3.23E-92 260 1588 "ABR,SYS1,TMCC3,GALNT13,PWWP2A,KIAA1211,MTUS1,ALCAM,ANK2,SUGT1P4-STRA6LP-CCDC180,APBB2,EPB41L5,PLA2G4C,MARK4,RASL11B,INSYN2B,ADAM23,ADAM15,ADGRB2,BARD1,SEC11C,BCL7A,SYNJ1,ARHGEF7,FUBP1,SCAPER,MTMR2,CACNA1G,CALB1,CAMK2B,CH25H,SPAG9,SLC16A4,ARHGEF1,SYNGR3,CACNA2D2,NPIPA1,CLTC,SRP14-AS1,HECTD1,TBPL1,MYRIP,CNRIP1,ZNF385A,CPS1,SEC31B,CDC42BPB,DZIP3,APPL1,UBXN2A,PLCXD3,DOCK4,RIPOR2,EARS2,MATR3,IP6K1,TMEM130,GSDME,GUCD1,SNAP91,SGSM2,DLX1,DMD,SLC29A4,CDON,ACOT8,RCAN1,DTNA,ABCC5,DNM1L,AASDH,EBF1,EDN1,HIPK3,FSD1L,FAM13A,EBI3,RASA4,C8orf37,EMX2,STX2,IGSF6,F5,CLVS1,TMEM132C,DLC1,ST3GAL6,FCGRT,SUCO,HPCAL4,FOXF2,SYNCRIP,FLNC,FLT1,PDLIM5,ATP2C1,MPP6,MEGF11,ZNF44,C15orf41,ALDH1L1,AHDC1,MALT1,HPGDS,ZNF638,GNG4,GPR37,TMEM121B,CNTRL,TPPP,GRIA2,ATE1,AP4S1,FAM222A,RASSF8,ITPKB,KIF5A,KIT,A1BG-AS1,LIMS1,SYTL4,HECTD2,MAN2A2,ZFYVE27,MARK1,MBNL1,PPM1L,ZNF680,ADAM22,MT1M,MYT1,NACA,NBL1,ZC3H12B,NFYA,CNOT4,NPTX1,NTRK2,ZNF827,DPY19L2P2,PCDH9,PDE4D,ENPP2,GPR85,ABCB1,PLIN1,PNMA3,POU6F1,PPP1R1A,PPP3CA,RASGEF1B,PRKACB,PRKCB,MTMR10,ELOVL2,SPDL1,PTPN13,PTPRD,TMEM231,PPP2R3C,RASGRF2,RDX,CRTAC1,GTDC1,ZDHHC4,RGS12,NUDT11,PBRM1,ROBO2,CCDC102B,NEK11,GLDN,SGSM1,STK32B,ABCA11P,RTN1,ZNF331,TRAPPC13,SEMA6D,GALNT10,MRAS,SCAF8,PPM1E,CHD9,R3HDM2,NLGN1,NUBPL,WDR37,SLA,PPP4R3A,ARHGEF40,ATF7IP,MAPKBP1,MBD5,TMCC1,MYO16,FAM219A,PDZD2,NMNAT2,TEX2,ZNF423,CDK19,ZBTB43,NFASC,LHPP,PBLD,CAMTA2,NKAIN2,SSPO,RGL1,SULF2,SYT1,SLC37A2,TAF6,MLST8,ADGRL3,AGTPBP1,MGRN1,TCF4,DMXL2,ZFP90,ZEB1,SZT2,PUM2,RNF216P1,PMS2CL,C18orf54,AP4E1,ZNF106,SLC44A1,ARL10,TMPO,KAT6B,TP53BP2,CHST5,TSC1,SSBP2,RPRM,USP1,MGAT5B,VSNL1,CLIP2,RICTOR,GUSBP1,SLC47A2,AGMO,TCEAL7,TMEM237,AMZ1,FTSJ1,ZNF213,ZFAND5,UPF3A,STOX2,MPPE1,DOCK8,JMJD1C,KLHDC1,GAN,FAM198A" MicroRNA hsa-miR-708:mirSVR_lowEffct hsa-miR-708:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.70E-94 1.51E-90 3.58E-93 3.29E-92 268 1685 "KCNH8,ASPHD1,NDRG2,ADCY6,CCDC85A,ADD2,PLEKHH1,AP2A2,ZNF608,HECW2,CC2D2A,AK2,ADGRF5,PCDH10,CDC42BPA,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,VAT1L,CDC14B,CDK10,IGDCC4,MARCH3,STX16,N4BP2L1,ADAM15,KSR1,SYNJ2,CASTOR3,MTMR2,CACNB4,KALRN,VXN,KYAT1,CBFA2T2,ENTPD6,LRBA,MAGI1,FOXN3,CHN1,PLEKHB1,TAOK2,RAB28,FBXO7,QKI,TMEM184B,LY86,FAM149A,WHRN,AKAP5,TOGARAM2,CREM,SH2B1,CRMP1,HAPLN1,CLIP3,AATK,ARHGEF10,SIPA1L1,GALNT9,VCAN,PDE4DIP,SLITRK5,PITPNM3,CTH,CCDC144A,ARHGAP32,IST1,ELMSAN1,DGCR5,HEPH,MYEF2,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DYNC1I1,CDON,DPH1,DRP2,E2F6,PHC2,HIPK3,TMTC1,FAM13A,EGR3,RASA4,RCAN2,EPHB1,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,PTK2B,FCGRT,FKTN,STRADA,FDFT1,ZNF589,MED12L,OLFM1,FGF11,MAD2L2,SUCO,UBE2E3,PCYOX1,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,UFM1,USP21,ZNF605,MEGF10,GAA,GABBR1,CHL1,GABRB3,DISC1,GATM,ALDH1L1,SESN1,DHRS4,RAB30,TOX3,TNRC6A,MSL3,ZNF638,ADGRA3,LILRB4,PRUNE2,PRDM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,MUM1,HMGCL,AGBL5,DHX35,SHISA6,SHISAL1,ZIC5,FAM69A,METTL21A,KCNF1,KCNK3,KCNN2,CREG2,IPO5,CYP27C1,L1CAM,SYTL4,SCAMP5,TAGLN3,HNRNPM,NF1,NNAT,NUCB2,OGG1,CDK18,PDE1B,GNG2,PFKFB2,PFKFB3,OLA1,PIK3R1,ZFYVE21,XRN1,KCTD15,PURG,PRIMPOL,ING3,POLR2F,POU6F1,PPARA,PRKAB2,MAPK4,EPDR1,MASP1,TMEM104,STK32A,PEX2,TMEM231,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RGS3,RGS4,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,ATP8B4,MAP6D1,NCBP3,FAM192A,CSRNP3,PRCD,SCP2,SEC14L1,GALNT10,FERMT1,SYBU,ABLIM3,PREX2,ARHGEF40,ATF7IP,ZFP1,GKAP1,SMARCC2,RCOR3,INAVA,SNRPN,SP4,KDM4C,IQSEC2,ZBTB43,RBM26,CLASP2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,JMJD6,PRRC2C,ARHGEF9,VPS13A,SYN2,DNMBP,TCF4,SYNE1,CCDC173,AP4E1,ASXL3,FAM124A,NPL,NEIL2,STXBP4,TRPS1,SSBP2,PRR18,UBTF,ZNF19,AMZ1,URM1,FAM47E,ST7,UBE3B,FAM198A,JPH3" MicroRNA hsa-miR-20b*:mirSVR_lowEffct hsa-miR-20b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.73E-94 1.53E-90 3.60E-93 3.31E-92 247 1435 "ABR,ACADM,ACHE,ACTN1,GALNT16,PWWP2A,ZNF608,RTL9,NME5,CC2D2A,TAOK1,ALCAM,LTBP4,AMPD2,AMPD3,MAP4K3,PHF12,APBA2,USP37,SEMA4G,DPY19L3,TTLL9,BACH1,BCHE,DNAJC27-AS1,SYNJ1,SCAPER,IL33,CACNA1B,PTBP2,CAMK2G,VXN,SPAG9,RUNX1T1,METTL6,LARGE1,CCPG1,NUMBL,CACNA2D2,SRSF11,B4GALT6,RAB28,NRXN3,QKI,CNN3,AKAP7,ARMC8,AKAP6,LETMD1,SLC35F1,CRY2,GDA,AATK,SNCAIP,SEC24C,LRRC3B,OSBPL3,VCAN,PDE4DIP,CYBB,EARS2,ZNF337,KIF26A,DGKB,DGKG,PABPC5,SPATA2,RAB39B,DMD,DNM1,NR1D2,SLC12A6,CASP8AP2,DNAJB6,GOLT1B,E2F5,WDPCP,EDNRA,EDNRB,RASGRP1,MRO,MBNL2,GOLGA7,EIF5,PLEKHA1,MRNIP,PAN3,DCTN4,RCAN2,STX2,CLVS1,SCML2,MEX3B,PCYOX1,SYNCRIP,FLT1,SLC37A3,SMC2,ATP2C1,AP4B1,GABRB3,ZNF274,IQGAP2,ERAP1,DISC1,KIAA1841,WASHC2A,AHDC1,GGT7,GHR,PPARGC1A,TCERG1,DBF4,CBX1,LUZP2,RAB40B,STON1,ADAMTS13,BTN2A1,FAM19A2,AP4S1,PSIP1,NXPH3,ELOVL5,HNF4G,LRRC75A,ZIC5,IL6ST,KIF2A,STXBP5,HECTD2,GPR155,MAT2A,MBD1,MEF2C,SRSF12,MSR1,MYO5A,NEXMIF,MYT1,NF1,NFE2L2,NFYA,NUCB2,P2RX7,CNTN3,PFKFB3,OLA1,PIK3C2A,MAGEL2,POLG,TATDN3,GDPD1,CNNM2,NCR3LG1,TMEM260,ZIK1,PTX3,RAD51D,RAP1GDS1,ENOX1,ERI2,GTDC1,PBRM1,ZNF532,TMLHE,ALG9,CARF,GSTCD,RORB,FBXW7,BAALC,ZC3H14,TCP11L1,RPS20,ATAT1,S100B,DGLUCY,SEMA6D,SATB1,ATXN7,SCN2B,SCP2,TRA2B,SH3GL3,PPM1E,CPEB3,MYO18A,SHC4,FBXO11,R3HDM2,ANKRD6,NUBPL,BTBD3,WDR47,CCDC88A,SLC11A1,SLC12A2,SLC14A1,ELMO2,ATF7IP,KIF13A,TMCC1,PDZD2,SOX15,SP2,ZSWIM8,NMNAT2,KDM4C,ERC1,ZBTB43,SPART,LMO3,CLASP2,STAU1,SEPT3,FAM208A,DMXL2,SATB2,TCF12,SZT2,SYNE1,C18orf54,AP4E1,SLC44A1,ARL10,BEX4,TP53BP2,STXBP4,TST,TUBB1,RPRM,UGT8,OSBP2,ZNF709,RICTOR,ZIC2,MICU3,KCNT2,ZNF154,ANKS1B,EVI5,STOX2,UBE3B,JMJD1C,FXR1,SENP7" MicroRNA hsa-miR-32:mirSVR_highEffct hsa-miR-32:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.77E-94 1.55E-90 3.64E-93 3.35E-92 222 1156 "SYN3,NCKAP5,TMCC3,KIAA1211,SLC24A4,TXNDC16,ALCAM,MARCH4,FAM135A,PITPNM2,DPP10,MARCH3,NCOA1,RASL11B,ATP2A2,ADAM23,ADGRB3,MPDZ,BCHE,HCN2,SYNJ1,ARHGEF7,CACNA1I,KALRN,CAMK2A,LDB2,MTMR7,L3MBTL4,SOCS6,NRXN3,HECTD1,CNRIP1,FAM171B,CREM,CRHBP,LRIG1,SOCS5,SLITRK5,ERC2,APPL1,PPP6R2,USP6NL,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,PLPPR4,WDR20,CDON,CPEB2,PDCD6IP,ARRDC4,ABCC5,DNM1L,E2F5,AASDH,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,DENND4A,FDFT1,POLK,FOXF2,ATP13A4,SLC37A3,UFM1,PDLIM5,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,CHL1,IQGAP2,ZNF559,DISC1,GHR,GLYR1,ZNF638,FERMT2,GPD2,LPAR4,GPR37,TPPP,DIDO1,FAM19A2,HAS2,ZHX1,MIER3,HNMT,MSL1,SLC6A17,C2CD4C,KIT,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,LRP1B,ZNF680,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,DNHD1,SMIM11A,CLDN11,P2RX7,GPR137C,PDE4D,GPR85,GNG2,PIK3R1,CCSER2,SNX10,ZFYVE21,PLCL1,JAKMIP1,PDZRN4,TRHDE,STRN3,SCHIP1,ING3,PPP2R5E,CEP41,SNRK,PTPRD,EML5,PTPRO,TMEM255A,ENOX1,RASGRF2,RDX,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RPE,RPL15,FBXW7,ABCA11P,AP1AR,SALL1,SATB1,FNIP1,SUPT20H,KIF21A,CPEB3,MYO18A,CHD9,CNKSR2,ZNF430,SLC12A2,SLC22A4,TET1,CPEB4,DMRTC1,CDK5RAP2,TTC17,LIMCH1,PDZD2,SOX11,MYCBP2,TEX2,PBLD,CLASP2,ITPRID2,ELOVL4,RGL1,SYN2,SYPL1,SYT1,CAMTA1,FBXW11,ATMIN,ZEB1,TCF12,SYNE1,DOCK9,SIK3,FAM200B,ERCC6L2,SYNPO2,TRIO,SGK3,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,TRIM9,ZNF142,ZSCAN26,EMSY,MFF,EVI5,RNF103,ADAMTS9,NAV3,RGS7BP,PHTF2,ADAMTSL3,FXR1,NETO2" MicroRNA hsa-miR-193b*:mirSVR_lowEffct hsa-miR-193b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-94 1.91E-90 4.48E-93 4.13E-92 279 1823 "EMILIN3,METAP1D,ADD2,ESYT2,KLHL13,RTL9,OSBPL1A,ALCAM,LTBP4,DOC2A,ANK2,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,AQP6,PPP4R4,ZFYVE28,CDK13,MARK4,NUMB,EIF4G3,STX16,SLC2A11,RNF182,ALDH7A1,ADGRB1,ADGRB3,BCHE,RGS11,NRP2,KSR1,BMP7,ARHGEF7,BTK,RAB29,CA8,CACNB4,CALM1,KALRN,VXN,CAST,RUNX1T1,LRBA,SEPT7,ZBED1,DIS3L,EPS15L1,TPP1,SULT4A1,IGLON5,ARHGEF6,CNR1,CNTN1,COL4A5,SUMF2,LETMD1,SLC4A8,ABI3BP,ENTPD4,SH2B1,AKAP12,ANKRD44,CLIP3,ABCG1,RGS6,ARHGEF10,PDE4DIP,GREB1,GPSM1,DOCK4,KATNAL2,TCAF1,CENPL,TBC1D5,MATR3,MAML1,BRINP1,ZBTB24,HEPH,ELMO1,KIAA0753,ZC3H11A,POM121,RHOBTB1,PLPPR4,WDR20,KIF19,CHRDL1,GRIN3A,DMTF1,SLC25A18,DTNB,MAMLD1,SNX29,FCF1,CNNM1,STARD3NL,EPHB1,MRPL37,TLR7,RASL12,SIRPB1,ABCA8,CHST15,GORAB,GTF2IRD2,FGF11,FGF13,POLK,UBE2E3,PCYOX1,FLT1,NOP56,FLYWCH1,EFCAB2,SPECC1,PDLIM5,FAM49B,STAMBP,ATP2C1,ZNF605,ABLIM2,CHL1,FAM120B,ZNF234,DISC1,GCK,GCNT2,SULT1C4,ADAM28,MALT1,ZNF276,SPIN1,KDM2B,KCNMB4,ZNF782,GRB10,GRIA2,GRIN2D,BVES,RABL2A,RNFT2,ADAMTS6,SLC2A6,ATOH8,MUM1,ZHX1,HNF4G,ZNF546,SCIN,ITPKB,METTL21A,KCNJ5,GATD1,KIF5A,CYP27C1,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,NCOA7,GPR155,MBNL1,CHST6,SCAMP5,POC1B,XRRA1,HS6ST3,RTL5,NF1,NPTX1,NRCAM,OLA1,DUSP26,GPSM2,ANKRD16,POLR2F,RASGEF1B,MAPK10,SLC26A11,CNNM2,PTPRG,ZNF615,PPP2R3C,PID1,CCDC40,SH3TC2,ZDHHC4,UBR7,RIC8B,CCDC82,ALG9,PNMA8A,ROBO1,ROBO2,SNX22,ATP8B4,SGSM1,PTGR2,MAPK12,SEMA6D,ATXN2,SCN2B,PRCD,SEC14L1,GALNT10,KIF16B,CHD9,FNDC3A,SEC31A,NUBPL,PEX26,BTBD3,KANSL3,SIRT2,ATF7IP,SLC22A4,MAST1,CDK5RAP2,SNRPN,ZSWIM8,HECW1,MYCBP2,ZBTB43,ATP10B,CLASP2,ITPRID2,SSTR2,CEP68,STAC2,ADHFE1,KANK1,KLHL7,ARHGEF9,ANKRD28,EXOC7,KLHL4,TCF4,DMXL2,ZFP90,TRIM2,SZT2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,SIK3,ZFPM2,PRRT1,CDK20,WBP2,CHST5,ZNF346,METTL3,AMACR,PPIL6,SSBP2,SGK3,SLC35A4,VIPR2,VSNL1,ZIC2,TCEAL7,ANKS1B,LAMP5,PRDM10,ADAMTS9,SLC17A7,FZD3,HNRNPA3,IFT88,NETO1,ST8SIA2" MicroRNA hsa-miR-1255b:mirSVR_lowEffct hsa-miR-1255b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-94 1.92E-90 4.49E-93 4.13E-92 264 1638 "DGCR6,ASIC1,SYS1,GALNT16,BRAP,PTCHD1,SLC24A4,ZNF578,C1QTNF3,FAM135A,OGT,PPFIA4,PKP4,APAF1,UPRT,PHYHD1,CPNE5,SPTBN4,MARCH3,ZBTB10,NCOA1,STX16,ZNF583,TTLL9,AZGP1,BACH1,BID,DST,ARHGEF7,SCAPER,SGCE,CFAP410,CACNA1B,CACNB4,HAP1,CAPN3,CBR1,ZNF501,CD86,ENTPD2,ARHGEF2,LRRFIP1,TIGD7,CLGN,DIS3L,SRSF11,TAOK2,PPT2,DGCR9,SRP14-AS1,CNGA3,FHL5,CNN3,AHCTF1,MYRIP,CPS1,FAM171B,MROH8,SOCS5,PDE4DIP,CNTNAP2,PHF14,FAM131B,RIPOR2,HDAC4,AIF1L,PITPNC1,ARMCX2,MFAP3L,C2CD2L,SGSM2,WDR20,ZNF582-AS1,DMTF1,CASP8AP2,PDCD6IP,TOM1,ABCC5,GOLT1B,E2F5,WDPCP,EDNRB,FSD1L,MBNL2,TMEM35A,STARD3NL,ENO2,COQ7,GPHN,STX2,DENND4A,ADGRV1,GMPR2,CORO2B,CEP78,FDFT1,KAT8,FER,FGF12,FGF13,FOXO3,SLC37A3,NOP56,AKAP3,NBEA,TPK1,ATP2C1,DLL3,STAU2,ABLIM2,ZNF559,DISC1,GATM,GCK,MSTN,GPR162,GGTA1P,PPARGC1A,RUNDC3A,ZNF276,CRCP,TCERG1,RNPS1,STARD3,POLL,GNAO1,LILRA2,PCLO,DIDO1,GRM2,FAM107A,SLC2A6,NXPH3,BACH2,ZNF491,CPT1C,SHISA6,SMAP1,ICA1,SLC35G1,METTL21A,STXBP5,KTN1,LAMP2,STMN1,LIMS1,NCOA7,PIK3AP1,MAPT,MATN2,MATN3,TM6SF1,MPP2,DBNL,COMMD5,PTOV1,MXI1,MYO6,MYO7A,NEXMIF,FXYD7,NEK1,NELL2,NFE2L2,NRCAM,SMIM11A,NTRK2,NUCB2,OCRL,OGG1,PCDH9,PFKFB2,SEMA5B,SNX10,NLE1,PLIN1,PNMA3,SDK2,MAGEL2,POU6F1,PRKACB,PRKCB,GRAMD1C,MASP1,VPS13C,PIGG,MTMR10,PTPRD,ZSCAN2,IQSEC3,MSANTD2,RDX,PRRT2,RNASE1,NUDT11,LGI2,DCUN1D2,TMLHE,ROBO1,RORB,ATP8B4,ATAT1,NCBP3,FAM192A,SCAF8,FAM102A,ASAP3,DZIP1,WDR37,SLC12A2,ELMO2,SLC22A4,GKAP1,CDK5RAP2,SNAP25,FAIM2,SNRPN,TSNAXIP1,KDM3A,IQSEC2,TSPYL2,TROVE2,POGZ,STX1A,KANK1,ARHGEF9,SYP,SLC37A2,SIN3B,ZEB1,DOCK9,PUM2,FRYL,ITGB3BP,AP4E1,ENHO,TMPO,FAM124A,CSMD1,TPM2,C9orf85,RGMB,STXBP4,TRPM2,TSC1,HSPBP1,BCL2L13,VLDLR,GUSBP1,XPO1,ZNF24,NDRG4,TCEAL7,REEP1,DNALI1,LINC02210,PPP1R3F,FAM13C,FZD3,UBE3B,KAT6A,RNF170,ZNF30,JPH3" MicroRNA hsa-miR-135b:mirSVR_lowEffct hsa-miR-135b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.51E-94 1.97E-90 4.59E-93 4.23E-92 282 1861 "NCKAP5,SYS1,FMNL2,KLHL32,TMEM132B,GALNT16,ADD1,ADD2,PWWP2A,BEND6,OLMALINC,HACE1,OSBPL8,CC2D2A,TAOK1,SEMA6A,UNC79,ZFAT,CDC42BPA,EP400,SUGT1P4-STRA6LP-CCDC180,PRX,NCOA1,ATP2B2,ZNF583,DPY19L3,LINC00847,HCN2,SYNJ2,MTMR2,GYG2,CFAP410,VXN,NFS1,METTL6,P2RX6,CD86,ZBED1,LRRFIP1,MAGI1,CDO1,CCPG1,FOXN3,NDST3,CPNE6,NRXN3,CLCN3,RAB26,CNGA3,CNN3,IQCK,PCYT1B,AKAP6,SLC4A8,ABI3BP,MYRIP,ZNF385A,SLC35F1,RNF14,NCOR1,GDA,SNCAIP,CSF1,PHF14,ARHGEF4,RIMS2,DOCK4,KATNAL2,GAPVD1,RIPOR2,DCAF8,MAML1,DBI,ARMCX4,RUSC2,C2CD2L,RHOBTB1,SACS,SV2B,WDR20,DYNC1I1,DOCK2,DMTF1,SLC12A6,DPH1,CASP8AP2,SLC25A18,DRP2,DTNA,FAM78B,WDPCP,EDN1,FCF1,MRO,KMT5B,COPS4,RGS17,DCTN4,EIF1,EPB41,APC2,VPS26C,DNAJC27,SIRPB1,EXTL2,CEP78,FCGR3A,GORAB,FER,AMOTL2,IP6K2,RGPD5,FLT1,SYT3,C2orf88,CHL1,GABRG1,GAD1,B4GALNT1,RAPGEF6,ZNF274,DISC1,CPLX1,ALDH1L1,CYP46A1,LYVE1,HPGDS,DBF4,STARD3,ZNF638,DCLK2,LNX1,ADGRA3,LILRB4,PRUNE2,PCLO,GRIA2,BTN2A1,BVES,ADAMTS6,MAP4K5,RASSF8,ZHX1,INSYN1,MIER3,NEGR1,AGFG1,SHISA6,MSL1,FAM95B1,GAREM2,RBPJ,LRRCC1,KCNB1,KIFC3,KIT,CYP27C1,KTN1,HECTD2,MAP2,MAP4,MARK1,MAT2A,MATN3,MEF2C,MEIS2,MEST,KCTD6,MID1,PPM1L,POC1B,MN1,MOV10,SAMD5,HS6ST3,NF1,ALDH1L2,DNHD1,NTRK2,NUCB2,GPR137C,PRTG,GPR85,PIK3C2A,ZNF655,CCSER2,SNX10,GPSM2,ANKRD16,KANSL1,SNRK,WDR25,CNTLN,BDNF-AS,ELOVL2,PTPRB,PTPRE,SH3TC2,OXR1,RBBP6,MSANTD2,REV3L,PRIMA1,RIC8B,SETD5,GSTCD,ROBO2,SPIN3,ZNF671,ATP8B4,GLDN,TCP11L1,ZNF331,SEMA6D,SCN2B,SCP2,MRAS,FAM102A,HKDC1,NLGN1,DZIP1,FAM81A,KBTBD4,ELMO2,ATF7IP,SMARCA4,RCOR3,MAPKBP1,TRERF1,NMNAT2,GLT8D1,TEX2,DBNDD2,IQSEC2,NFASC,ATP10B,ZC4H2,JMJD6,PRRC2C,VPS13A,PLCB1,COBL,CAMTA1,DNMBP,TCF4,ZEB1,RPGRIP1L,PCDHA5,DICER1-AS1,ZFPM2,GPR161,TIAM1,MTMR14,TNS1,TPM1,NEIL2,TRO,STXBP4,RUSC1,UBE2H,OSBP2,PLEKHH2,ZNF28,ZNF154,EML6,SPIRE1,SMARCAD1,SLC38A1,ADAMTS9,FAM47E,TRIM16L,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,ACTR3B,TRAM2-AS1,MSRB3,TTC7A,FRMD6,SOCS4" MicroRNA hsa-miR-19b-2*:mirSVR_highEffct hsa-miR-19b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.58E-94 2.56E-90 5.97E-93 5.50E-92 237 1324 "KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,VAT1L,PPP4R4,SPTBN4,NUMB,EIF4G3,BACH1,BCL7A,ARHGEF7,MTMR2,SGCE,IL33,CACNA1B,CACNA2D1,CALM1,KALRN,PTBP2,CAMK2G,CAST,LRRFIP1,NOG,CACNA2D2,CFL2,CBARP,SOCS6,NRXN3,PLAA,PPT2,FBXO7,FAM189A2,C4orf33,ARMC8,RCHY1,MYRIP,IGDCC3,SLC35F1,FAM171B,CLOCK,SUSD5,PLXNA4,PHF14,CTH,USP6NL,ARHGAP32,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,RHOBTB1,FAM107B,NR1D2,CPEB2,DTNA,EDN1,EDN3,EDNRB,RASGRP1,PHF20L1,EGFR,EIF4G2,EMX2,LRRC17,CEP85L,CDKL3,TLR7,TMEM132C,TAOK3,DLC1,FDFT1,SUCO,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,ATP2C1,CELF1,MEGF10,CHL1,MTHFD2,GATM,NEU3,ARFIP1,AHDC1,ADAM28,TXNL4A,GLI2,ZNF638,GNAO1,FERMT2,GRB10,SOX21,HAS2,FRMD3,ARHGAP36,HNF4G,NEGR1,SHISA6,KCND2,KCNN3,STXBP5,LAMA2,PAXBP1,ASPRV1,PIK3AP1,MARK1,MATN2,EFHB,KCTD6,MIA2,PPM1L,MITF,ZNF680,MYO9A,SFR1,NF1,NFE2L2,SMIM11A,OGG1,OPA1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,PDE4D,GNG2,OLA1,NLGN3,FAM218A,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,PRKCB,MAPK10,HYDIN,ELOVL2,PTK2,PTN,STK32A,PTPN13,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RNASE1,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,SPIN3,MCMBP,ABCA11P,HSD11B1L,RTN1,SATB1,ATXN7,SCN7A,FNIP1,KIF21A,CPEB3,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,MYO16,KDM3A,SP4,ZC3H13,ZC4H2,NXT2,RGL1,VPS13A,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,PCDHB9,OBSL1,PUM2,FRYL,ASXL3,NR2E1,TMPO,C9orf85,SYNPO2,TRO,ANKRD20A2,TUBB1,RPL7L1,FAM155A,VLDLR,P2RY12,GUSBP1,XPO1,XRCC4,CFAP298,ZNF28,KCNT2,ZNF540,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,ZNF195,SPIRE1,STOX2,TMEM178A,NAV3,PDSS2,FZD3,KLHDC1" MicroRNA hsa-miR-4303:mirSVR_lowEffct hsa-miR-4303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-94 2.68E-90 6.23E-93 5.74E-92 276 1788 "ABCF1,ACHE,CLK4,FMNL2,ADCY6,ADD1,ADD2,PTCHD1,KLHL13,CC2D2A,C1QTNF1,C1QTNF3,SEMA6A,AMPD3,CDC42BPA,DPP10,APBA2,IGDCC4,CASK,LINC00173,NUMB,ZNF583,ADAM15,BARD1,CFLAR,KSR1,BMPR1B,ARHGEF7,CASTOR3,CACNA1G,WASF1,MYRF,CFAP410,CBS,CDH2,L3MBTL4,CCPG1,CFL2,DGCR9,FBXO7,VAX2,C4orf33,HECTD1,MAP4K4,ARMC8,SMARCAL1,IGDCC3,ANKRD44,GDA,CS,CSF1,OSBPL3,PHACTR3,DZIP3,PHF14,CYBB,LONRF1,IST1,DGKB,GIT2,MYEF2,RUSC2,SGSM2,GRIN3A,DMD,HS3ST2,DOCK2,DMTF1,MAMLD1,DNM1L,WDPCP,EDN3,PHC2,ANKRD46,HIPK3,CNNM1,HEYL,KLHL5,EGFR,EGR3,EIF4G2,COPS4,STARD3NL,RCAN2,ENPP6,STX2,ETV1,MRVI1,DLC1,FCGR1A,FCGRT,FGF11,AMOTL2,ATP13A4,NELFCD,NBEA,SPECC1,APOPT1,USP21,MSANTD4,AP4B1,DOT1L,FYN,MEGF11,HRASLS5,TRAF3IP2,ACSS1,GPR162,CYP46A1,GGT7,GHR,LYVE1,MSL3,LNX1,GPD1,STON1,GRB10,GRIA2,GRM2,ZNF496,LINC01089,PTPRT,ZBTB49,RASSF8,HAS2,MAN1B1,VSIG4,SYNPO,DHX35,SMAP1,ICA1,FAM95B1,MYLK2,INPP5B,NME9,KCNN2,KHK,IPO5,KTN1,SFXN5,NCOA7,MAP6,LYPLAL1,MAT2A,AQP11,MGAT3,MMP16,NCAM2,ZC3H12B,SFR1,NF1,NINJ2,SLC11A2,NRCAM,TBC1D25,P2RY1,PAX6,PDE4D,GNG2,ZNF655,RETREG1,TMEM38A,PLCD1,ANKRD16,PMP22,MAPKAP1,EPB41L4B,POU6F1,PPARA,MINDY2,RASGEF1B,PRKACB,PKIA,NDUFS7,DEF8,PTCH1,PTPRG,ZSCAN2,PPP2R3C,USP47,ACSS3,RASGRF1,RASGRF2,RBBP6,ZDHHC14,ZMAT4,MORC4,RGS3,PRIMA1,RNASEL,RNH1,CCDC82,ZNF532,CARF,GSTCD,ROBO2,CCDC25,ELP2,SNX22,NEK11,RPL15,ARMH4,ZC3H14,MCMBP,LRRK2,ABCA11P,HSD11B1L,CLIP1,SCN8A,CASC3,MRAS,SUPT20H,KIF27,SH3BGR,ASAP3,NLGN1,ANKRD6,SEPHS1,CCDC88A,TET1,CDK5RAP2,SNAP25,MAPKBP1,MBD5,TMCC1,DOP1A,BDP1,HECW1,MYCBP2,CAMTA2,POGZ,ZC4H2,STAC2,KANK1,VPS13A,TAF6,ADGRL3,KLHL4,MGRN1,SATB2,RPGRIP1L,TNS2,HIF3A,CYB561A3,RNF216P1,SLC44A1,BHLHB9,LRRC8A,R3HDM1,TP53BP2,TRIO,AMACR,RUSC1,KCNE5,SSBP2,CLHC1,UGT8,WIPF1,LGI4,KCNT2,ZNF142,AMZ1,STOX2,ADAMTS9,FIP1L1,PDSS2,FZD3,DOCK8,RNF170,MSRB3,AP3B2,ZNF30,PRRT4,FAM198A,SENP7,JPH3" MicroRNA hsa-miR-3129:mirSVR_lowEffct hsa-miR-3129:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.64E-94 3.72E-90 8.62E-93 7.94E-92 253 1511 "ACADM,AS3MT,PLEKHH1,BEND6,INTS2,HECW2,OSBPL1A,TBC1D14,WDR35,CC2D2A,HFM1,SEMA6A,ARHGAP20,FAM135A,SYT13,AMPD2,ZFAT,LCORL,APBB2,USP37,TMEFF1,ZFYVE28,ARNTL,NUMB,N4BP2L1,TTLL9,CFLAR,CACNB4,CALB1,VXN,PRC1,CBFA2T2,ARHGEF2,LOC730101,CCPG1,NOG,NUMBL,CNOT8,NDST3,NRXN3,PLAA,PPT2,CLCN3,C4orf33,SLC4A8,MAGED1,RCHY1,ZFP28,CDC42BPB,RBM39,AKAP12,ARHGEF10,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,SEC14L5,CCDC144A,HDAC9,TBC1D5,TMEM170A,DAPK1,GIT2,ARMCX2,KLHL3,PLPPR4,SLC29A4,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,YAF2,CELSR3,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,EPHB1,ENPP6,GPHN,ERBB4,MRPL37,PIPOX,F5,FAM198B,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,SYNCRIP,RGPD5,FLT1,ANKFY1,FAM49B,ATP6V1H,ATP2C1,KHDRBS3,NSG1,MPP6,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GNAL,LNX1,PRUNE2,TPPP,GRB10,KAT7,ZBTB49,FAM222A,IRAK3,FRMD5,BACH2,AGBL5,KCND2,IPO5,STXBP5,CYP27C1,ZFYVE27,MAPT,MBD1,LRP1B,MEF2C,MEIS1,PPM1L,AFDN,ZNF680,LYRM9,LAYN,P2RY13,ZC3H12B,NFYA,NTRK2,SETD4,OPA1,GPR137C,CCSER2,ZFYVE21,PKM,FAM216A,STRN3,PPM1B,TATDN3,PPP3CA,PRKACB,MAPK4,HYDIN,DIRAS2,VPS13C,WDR25,PIGG,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,TUG1,FAM184A,RDX,DPF2,RFX2,RGS3,SLC25A36,TMLHE,EXD2,KLHDC8A,ROBO2,CCDC25,ELP2,RPL15,SPIN3,TCP11L1,RPS6KA2,ABCA11P,ATXN7,TNFRSF19,TRA2B,SCAF8,MYO18A,SHC4,FBXO11,CCDC92,NLGN1,PEX26,CCDC88A,SLC12A2,FAIM2,KDM4B,BDP1,RBM26,SPART,NFASC,ATP10B,ITPRID2,SSTR1,STAU1,ADHFE1,KLHL7,DNMBP,FAM208A,ADGRL3,FBXW11,ZEB1,TRIM2,DOCK9,DNAH7,DICER1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,ZNF106,AKTIP,CDH22,NACC2,RIMBP2,TTC3,USP1,CFAP298,PCDH20,ZFP37,ZBTB14,LYPD6,SLC38A1,PRDM10,HPS4,NAV3,FAM47E,DNAH10,FZD3,HNRNPA3,PHTF2,TIGD6,MSRB3,SOCS4" MicroRNA hsa-miR-3168:mirSVR_lowEffct hsa-miR-3168:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.71E-94 4.32E-90 9.99E-93 9.20E-92 253 1512 "ASIC1,AS3MT,TMCC3,PLEKHH1,OLMALINC,HECW2,KLHL13,TBC1D14,CC2D2A,C1QTNF3,SMIM17,SRPX,CEP126,OGT,ANK2,EP400,SLC4A4,N4BP2L1,DPY19L3,BCHE,BMPR1B,ARHGEF7,MTMR2,CA12,DDR1,CALM1,PTBP2,CAST,RUNX1T1,CBR1,CLDN10,ZBED1,FOXN3,CNOT8,NGEF,ARHGEF6,ARMC8,LETMD1,AKAP5,RCHY1,FAM171B,C2CD2,CREM,ENTPD4,AKAP12,HAPLN1,TRIM69,CS,PHF14,CYBB,HDAC9,KATNAL2,MATR3,YTHDC1,JAKMIP2,MFAP3L,KLHL3,GSDME,DMPK,USP3,NR1D2,DOCK2,ACOT8,PDCD6IP,GOLT1B,EBF1,EDNRA,KMT5B,IRAK4,TENM1,PAN3,USPL1,EMX2,RCAN2,ZNF549,KATNAL1,F5,FAM198B,ZNF461,TMEM132C,ACSL4,SCML2,CORO2B,DLC1,FCGR3A,SLC9B2,POLR1B,FGF12,FGF13,MEX3B,PCYOX1,FOXO3,JKAMP,SMC2,APOPT1,UFM1,ATP2C1,CHL1,GABRG2,FAM120B,RAPGEF6,IQGAP2,MTHFD2,GATM,SPIN1,ZNF638,LPAR4,GPR34,STMN2,ATE1,RNF165,GSTM5,IRAK3,RASSF8,FRMD3,HMGCR,HSPA1L,NKD1,ZIC5,IL6ST,LRRTM1,KCND2,KIF2A,KIFC3,LAMP2,PAXBP1,SYTL4,MARK1,MBD1,LRP1B,KCTD6,KITLG,MMP16,ADAM22,MSR1,NCAM2,ZC3H12B,NEFM,CNOT4,NOVA1,NPTX1,NTRK2,NUCB2,GLIPR1L2,PDE1C,PDE4D,NALCN,PIK3C2A,SNX10,PKM,PLCL1,LRP12,SCHIP1,SEPT4,EPB41L4B,MINDY2,RANBP3L,PRKAB2,MAPK9,MASP1,BCAS3,PTCH1,PTPRD,PTPRO,CCDC40,FAT4,RASGRF2,ERI2,PRIMA1,RIC8B,LGI2,ROBO1,SNX22,ZC3H14,TCP11L1,LRRK2,SATB1,ATXN2,SCP2,TNFRSF19,SMPD3,KIF16B,CPEB3,SHC4,NLGN1,SLC9A5,SLC12A2,BTBD7,SMARCC2,ANKRD36,SNAP25,MAPKBP1,KIF13A,CMTR2,SNRPN,FAM126B,MYO16,KDM4C,ZBTB43,SPART,ITPRID2,SAMSN1,ERBIN,ELOVL4,SEPT3,NSFL1C,KLHL7,NECAB1,PRRC2C,COBL,ANKRD28,TACC1,TBCEL,FBXW11,TBL1X,SATB2,TRIM2,SZT2,SYNE1,DOCK9,PCDHB9,PCDHB6,GPRIN3,HIF3A,TEK,HEY1,TLR4,CSMD1,C9orf85,ZNF346,TRPS1,SSBP2,RPRM,UBE3A,BCL2L13,WIPF1,MICU3,ZBTB38,SLC30A4,RNF103,ITM2C,FAM47E,PDSS2,FZD3,PHTF2,CASC15,FAM219B,ADAMTSL3,NLRP3,TIGD6,SNX14,FRMD6,FAM198A" MicroRNA hsa-miR-3139:mirSVR_lowEffct hsa-miR-3139:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.31E-94 4.65E-90 1.07E-92 9.88E-92 271 1730 "KCNH8,ASPHD1,NDRG2,ADCY6,CCDC85A,ADD1,ADD2,PTCHD1,AP2A2,ZNF608,MTUS1,HECW2,CC2D2A,AK2,ADGRF5,PCDH10,SYT13,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,PHYHD1,VAT1L,CDK10,MARCH3,NCOA1,STX16,N4BP2L1,ADAM15,BACH1,MIR9-3HG,KSR1,SYNJ2,CASTOR3,MTMR2,KALRN,VXN,HIP1R,KYAT1,CCNH,CBFA2T2,CD38,ENTPD6,LRBA,MAGI1,FOXN3,CHN1,PLEKHB1,RAB28,DGCR9,FBXO7,QKI,TMEM184B,SRP14-AS1,LY86,FAM149A,WHRN,TOGARAM2,CREM,SH2B1,CLIP3,AATK,ARHGEF10,GALNT9,PLXNA4,SLITRK5,PITPNM3,CTH,CCDC144A,DOCK4,IST1,ELMSAN1,DGCR5,HEPH,MYEF2,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DYNC1I1,DPH1,E2F6,PHC2,HIPK3,FAM13A,EGR3,RASA4,C3orf18,EPHB1,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,PTK2B,FCGRT,FKTN,STRADA,FDFT1,ZNF589,MED12L,OLFM1,FGF11,SUCO,UBE2E3,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,USP21,ZNF605,CELF1,MEGF10,GAA,GABBR1,CHL1,DISC1,GATM,ALDH1L1,SESN1,USP19,DHRS4,RAB30,TOX3,MSL3,ZNF638,ADGRA3,PRUNE2,PRDM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,MUM1,HMGCL,AGBL5,SHISA6,SHISAL1,ZIC5,DISP2,FAM69A,METTL21A,KCNK3,CREG2,KIT,CYP27C1,L1CAM,SFXN5,SYTL4,LSS,SCAMP5,TAGLN3,HNRNPM,NF1,NNAT,VWA2,NUCB2,CDK18,PDE4A,PDE1B,GNG2,PFKFB2,PFKFB3,OLA1,PIK3R1,ZFYVE21,XRN1,KCTD15,MTRF1L,PLXNB1,PURG,PRIMPOL,POLR2F,POU6F1,PPARA,PRKAB2,MAPK4,EPDR1,GRAMD1C,MASP1,TMEM104,STK32A,TMEM231,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RGS3,RGS4,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,MCMBP,ATP8B4,NCBP3,FAM192A,CSRNP3,PRCD,SCP2,SEC14L1,FOXRED1,FERMT1,SYBU,ABLIM3,PREX2,ARHGEF40,ATF7IP,GKAP1,SMARCA4,SMARCC2,CDK5RAP2,ANKRD36,SNRPN,SP4,KDM4C,IQSEC2,CDK19,ZBTB43,RBM26,CLASP2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,JMJD6,ARHGEF9,VPS13A,PLCB1,SYN2,TACR1,ANKRD12,DNMBP,TCF4,RPGRIP1L,SYNE1,NSD1,CCDC173,AP4E1,ASXL3,FAM124A,NPL,CHST5,SMUG1,NEIL2,TRPS1,SSBP2,PRR18,UBTF,CLDND1,ZNF19,ZNF70,AMZ1,URM1,UBE3B,FAM198A,JPH3" MicroRNA hsa-miR-526a:mirSVR_lowEffct hsa-miR-526a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-94 4.71E-90 1.08E-92 9.92E-92 259 1584 "ASIC1,NCKAP5,SYS1,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,INTS2,ZNF578,ALCAM,ARHGAP20,FAM135A,LRCH2,APBA2,APC,EPB41L5,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,SRP14-AS1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,DNAL1,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,NALCN,SNX10,PLIN1,PDZRN4,SH3KBP1,PRKAB2,MAPK10,GRAMD1C,HYDIN,QRICH1,CNTLN,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,MYO16,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-518d-5p:mirSVR_lowEffct hsa-miR-518d-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-94 4.71E-90 1.08E-92 9.92E-92 259 1584 "ASIC1,NCKAP5,SYS1,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,INTS2,ZNF578,ALCAM,ARHGAP20,FAM135A,LRCH2,APBA2,APC,EPB41L5,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,SRP14-AS1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,DNAL1,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,NALCN,SNX10,PLIN1,PDZRN4,SH3KBP1,PRKAB2,MAPK10,GRAMD1C,HYDIN,QRICH1,CNTLN,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,MYO16,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-520c-5p:mirSVR_lowEffct hsa-miR-520c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-94 4.71E-90 1.08E-92 9.92E-92 259 1584 "ASIC1,NCKAP5,SYS1,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,INTS2,ZNF578,ALCAM,ARHGAP20,FAM135A,LRCH2,APBA2,APC,EPB41L5,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,SRP14-AS1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,DNAL1,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,NALCN,SNX10,PLIN1,PDZRN4,SH3KBP1,PRKAB2,MAPK10,GRAMD1C,HYDIN,QRICH1,CNTLN,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,MYO16,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-518f*:mirSVR_lowEffct hsa-miR-518f*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-94 4.71E-90 1.08E-92 9.92E-92 259 1584 "ASIC1,NCKAP5,SYS1,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,INTS2,ZNF578,ALCAM,ARHGAP20,FAM135A,LRCH2,APBA2,APC,EPB41L5,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,SRP14-AS1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,DNAL1,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,NALCN,SNX10,PLIN1,PDZRN4,SH3KBP1,PRKAB2,MAPK10,GRAMD1C,HYDIN,QRICH1,CNTLN,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,MYO16,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-549:mirSVR_lowEffct hsa-miR-549:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.94E-94 5.00E-90 1.14E-92 1.05E-91 249 1466 "NCKAP5,XKR4,KLHL32,USP31,ESYT2,DPY19L2P4,PCDH19,SMIM17,SEMA6A,ALCAM,UNC79,DPP10,LRCH2,PARG,GAS7,USP37,ARNTL,NUMB,STX16,BMP7,CA8,CACNA1B,CALM1,PTBP2,CAMK2G,ISPD,RUNX1T1,CBR1,ZNF501,METTL6,CBFA2T2,MAGI1,DLGAP1,DIS3L,SRSF11,CHN1,CNOT8,C7orf61,RAB28,NRXN3,ABCG2,CNTN1,ZNF521,CREM,CSF1,SUSD5,SOCS5,PDE4DIP,PLXNA4,RASGEF1C,KIAA0040,DCAF4,DOCK4,KIAA0586,KCTD8,SPOCK2,ARMCX4,ARMCX2,PLPPR4,SNAP91,WDR20,FAM107B,DMD,HS3ST2,USP3,DOCK2,DPH1,RCAN1,ECM2,DNAJB6,DNM1L,GOLT1B,ANKRD46,HIPK3,RASGRP1,TMTC1,FRY,CELSR3,SUGP2,EIF4G2,EIF5,PLEKHA1,RGS17,DENND4A,ZNF549,ADGRV1,EYA1,ARMCX1,FCGRT,ZSCAN30,STRADA,FGF11,FGF13,TMEM164,PRKAG2,SYNCRIP,ANKFY1,SPECC1,UFM1,PRELID3A,ST6GALNAC3,DLL3,FAM120B,MTHFD2,ZNF559,INPP5K,TUBGCP4,GFRA2,TOX3,KDM2B,GPR37,GRB10,DIDO1,GRM2,COQ10A,IRAK3,FRMD3,AGBL5,MSL1,IDH3A,NKD1,IL12A,ITPKB,STXBP5,L1CAM,LAMP2,LMO2,PACRG,MARK3,MATN3,LRP1B,KCTD6,SAMD5,MXI1,MYCN,LYRM9,MYO5A,NEXMIF,HNRNPM,NCAM2,ZC3H12B,NFYA,GPR137C,PDE1C,OLA1,SNX10,XRN1,NLE1,TRHDE,SH3KBP1,PPP2R2C,PPP3CC,RANBP3L,EPDR1,PRPSAP2,RELN,APTX,QRICH1,PTN,TMEM260,PTPRO,PTX3,TUG1,TMEM231,ENOX1,RBBP6,RADX,KHDRBS2,GTDC1,RFX3,PRIMA1,PBRM1,SETD5,CYB561D1,ROBO2,FBXW7,ZC3H14,ATP8B4,CASC3,FOXRED1,KIF21A,FNDC3A,NUBPL,WDR47,FAM214B,KDM4D,SLC8A1,SLC12A2,BTBD7,EPC1,GKAP1,CDK5RAP2,MBD5,CABCOCO1,SNRPN,PDZD2,SOX11,SP2,KDM4C,ERC1,MCF2L2,POGZ,LARP4,ELOVL4,RGL1,SYNE2,PJA1,CAMTA1,AGTPBP1,DMXL2,TPCN2,USP22,OBSL1,USP32P1,RNF175,TEK,SIRT1,ITGB3BP,AP4E1,MTMR14,HEY1,TLR4,BEX4,TNS1,TP53BP2,SYNPO2,METTL3,TRO,CA14,TTTY15,TTC3,EIF4ENIF1,PLEKHH2,ZNF709,ZNF708,ZNF28,CELF4,TMEM237,INTS3,TUBA1A,VPS35L,FZD3,MARCH8,PHTF2,ADAMTSL3,JMJD1C,KLHDC1,IFT88,LAS1L" MicroRNA hsa-miR-361-5p:mirSVR_highEffct hsa-miR-361-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.90E-94 5.54E-90 1.26E-92 1.16E-91 234 1295 "RALGAPA1,CLK4,NDRG2,ADORA1,BEND6,MTUS1,HACE1,FAM135A,DPP10,PHF12,PKP4,BCAS1,TNRC6C,ARNTL,ZBTB10,DPY19L3,ZNF599,BMP7,ARHGEF7,CA8,RUNX1T1,CBLN1,KRIT1,SLC16A4,CDH2,MAGI1,SRSF11,B4GALT6,CNOT8,NDST3,RAB28,QKI,MAP4K4,AKAP7,ARMC8,AKAP6,LETMD1,AKAP5,ZNF521,ZFP28,CLOCK,AKAP12,NCOR1,CS,SNCAIP,RGS6,LRRC3B,CST3,ERC2,UBXN2A,PHF14,CYBB,HDAC9,DGKB,PITPNC1,ZNF804A,MYEF2,DDX46,ALKBH8,MTX3,GRIN3A,DMD,PDCD6IP,E2F6,EBF1,EDIL3,EDNRA,ANKRD46,OPTN,FAM13A,MBNL2,KMT5B,C8orf37,CALCRL,RCAN2,GPHN,STX2,DENND4A,RRAGB,ADGRV1,ABCA8,TAOK3,CEP78,GORAB,FER,FGF1,RGPD5,ANKFY1,SLC37A3,SMC2,STAMBP,ATP2C1,MSANTD4,GALC,GATM,SULT1C4,GPR75,ZNF638,FERMT2,PCLO,BTN2A1,AP4S1,RABL2A,GUCY1B1,FAM95B1,RBPJ,KCNJ16,KIF5A,HECTD2,GPR155,MAP2,MBNL1,MEST,KCTD6,AFDN,MXI1,MYO9A,NDP,SFR1,NF1,ZNF713,TREM2,CNTN3,PCDH9,PDE3A,PDE4B,PDPK1,GPR85,PIK3R1,GPSM2,FAM216A,PCDH18,ANKRD16,POLR2F,MINDY2,PPM1B,KANSL1,PRKACB,PKIA,PRKCB,MAPK9,GRAMD1C,RELN,VPS13C,WBP1L,PIGG,CNTLN,STK32A,ZSCAN32,TTC13,PPP2R3C,CEP97,RAP1GDS1,OXR1,REV3L,ERI2,RFX3,UBR7,SUGCT,CARF,ROBO2,RORB,ELP2,ATP8B4,TCP11L1,PTGR2,TRAPPC13,ATXN7,SCAF8,SGK1,CHD9,SEC31A,SLC8A1,CCDC88A,NAPB,TET1,ANKRD36,CMTR2,MYO16,PDZD2,FNBP1,ATP10B,ZC4H2,STAU1,RGL1,DIP2A,ADHFE1,KLHL7,RHBDL3,VPS13A,COBL,ANKRD28,DMXL2,ZFP90,ZEB1,RPGRIP1L,PCDHGB7,SYNE1,PCDHB9,PCDHB6,PCDHB4,FRYL,PMS2CL,ZFPM2,TIAM1,ERCC6L2,CSMD1,NPL,RGMB,DCBLD1,UGT8,MTCH1,WNT7A,XRCC4,ZNF24,MICU3,MKRN3,TCEAL7,ZBTB38,EML6,SLC30A4,TMEM178A,HPS4,PLSCR4,PARP11,EPM2A,HRASLS,FAM13C,FZD3,FBXO36,ACTR3B,JMJD1C,DPF3,GAN" MicroRNA hsa-miR-559:PITA hsa-miR-559:PITA_TOP PITA 1.17E-93 6.53E-90 1.49E-92 1.37E-91 191 848 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,ETV1,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,BTBD7,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-532-3p:mirSVR_lowEffct hsa-miR-532-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-93 1.18E-89 2.68E-92 2.46E-91 285 1913 "ASPHD1,ACADM,SYS1,ACTN1,FMNL2,KLHL32,ADORA1,RNF150,LRFN2,MTA3,PCDH10,PDZD4,AMPD2,AMT,OGT,SUGT1P4-STRA6LP-CCDC180,EPB41L5,LGR5,MADD,MARK4,ZNF583,SLC2A11,TTLL9,AZGP1,CFLAR,BMP7,FUBP1,MTMR2,GYG2,CACNA1G,MYRF,DDR1,KALRN,PTBP2,CAMK2B,VXN,CAST,HIP1R,ARHGEF25,CBLN1,KRIT1,METTL6,P2RX6,CDC25B,ZMYM4,MAGI1,UBE2L6,PPT2,ABCG2,MAP4K4,LY86,IQCK,LETMD1,COX4I1,RNF14,ABCG1,SNCAIP,ARHGEF10,SIPA1L1,PDE4DIP,CTH,GREB1,RUBCN,CYBB,ARHGAP24,DCAF8,RASSF2,KCTD8,INTS1,SCRN1,SPOCK2,ARMCX4,FBXL5,KIAA0753,RUSC2,C2CD2L,KIAA0319,GUCD1,WDR20,SEC16A,USP3,CDON,DMTF1,ACOT8,DRP2,ARRDC4,DTNA,FARSB,EBF1,EDN3,EDNRA,EDNRB,CNNM1,MRO,MBNL2,ING4,C3orf18,DCTN4,ENO2,MFSD10,COQ7,LRRC17,SRRM1,DENND4A,ZNF391,ETV1,SIRPB1,MRVI1,EZH1,NRN1,CLVS1,CEP78,FGF1,FGF14,SUCO,IP6K2,VTI1B,FLT1,ANKFY1,ZNF605,CGREF1,ZMAT1,GABBR1,HRASLS5,GABRA3,GAD1,ERAP1,SIGLEC8,C15orf41,LRRC37A6P,ARFIP1,USP19,DHRS4,CRCP,TNRC6A,LILRB4,ADAMTS13,RNF165,GSTM5,RABL2A,LINGO1,PSIP1,RASSF8,TOX2,PADI2,TNFAIP8L3,ARHGAP36,ELOVL5,CPT1C,SMAP1,MSL1,ZNF678,KCND1,MBP,MEIS1,MMP16,MYO9A,RTL5,NBL1,NEFM,NELL2,NF1,NFYA,DNHD1,NUCB2,IGSF11,OPRL1,PDE4A,ZDHHC8,NALCN,ZFYVE21,GPSM2,TRHDE,STRN3,LRP12,EXOSC10,SEPT4,POLR2F,PPP1R1A,CCDC144B,VSTM2L,PRKAR1B,MAPK3,MAPK4,DCHS2,MASP1,NDUFS7,PIGG,CNTLN,NCR3LG1,BDNF-AS,ELOVL2,TMEM260,STK32A,PTPRG,ZSCAN2,PID1,SH3TC2,GAL3ST4,DPF2,RFX3,RGS3,KIF7,KLHL11,SUGCT,C12orf49,GSTCD,CYB561D1,ROBO2,RORB,PCMTD2,ZC3H14,RPS6KA2,ZNF331,ATXN7,SCN8A,PRCD,GALNT10,STUM,ZFP30,FRMPD1,MYO18A,SHC4,ST6GAL1,ANKRD6,FAM214B,PKNOX2,RADIL,ARHGEF40,SLC14A1,CDK5RAP2,KIF13A,SNRPN,NMNAT2,IQSEC2,SPART,LHPP,DIP2A,STAC2,NSFL1C,JMJD6,SYN2,SYP,TACC1,MTCL1,MLST8,DNMBP,PDLIM2,ALG1,ZEB1,SLC19A3,FRYL,DICER1,DICER1-AS1,AP4E1,ZNF106,THRA,TMEM9,TP53BP1,NPL,CHST5,DCBLD1,SSBP2,ZKSCAN5,UBE2H,UBTF,UCHL1,GORASP1,USP1,PLPPR2,CLDND1,LGI4,TRIM9,ZNF74,POLR3H,PCBP1-AS1,EMSY,VPS35L,SEMA3B,PCBP4,PARP11,HRASLS,FAM219B,LAS1L,PRRT4" MicroRNA hsa-miR-4310:mirSVR_highEffct hsa-miR-4310:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-93 1.30E-89 2.94E-92 2.71E-91 237 1334 "ABCF1,FMNL2,GALNT13,ADD2,PLEKHH1,PWWP2A,KIAA1211,DPY19L2P4,MTUS1,KLHL13,KCTD16,SPOP,ARHGAP20,GPRASP2,OGT,CDC42BPA,BCAS1,ZFYVE28,MARCH3,EIF4G3,ZNF582,N4BP2L1,DOCK11,NRP2,BLM,ZNF599,MTMR2,C5,CACNA2D1,THSD7A,PRC1,CD86,ZBED1,COPB2,SRSF11,RAB33A,CLCN3,ABI3BP,AHCTF1,CREM,HAPLN1,CRYM,SNCAIP,OSBPL3,VCAN,DZIP3,APPL1,PPP6R2,RUBCN,DOCK4,ZFYVE16,CENPL,IST1,DGKB,YTHDC1,JAKMIP2,DDX46,POM121,WDR20,KIF19,DLX1,DMD,DMTF1,ECM2,FAM78B,DNAJB6,E2F6,EBF1,TSPAN5,FRY,PHF20L1,MBNL2,PLEKHA1,TUBD1,COQ7,RCAN2,LRRC17,CEP85L,F5,ZNF461,ACSL4,GORAB,OLFM1,FGF11,FGF13,PRKAG2,VTI1B,ATP13A4,FLT1,DCTN2,SMC2,CELF1,NSG1,STAU2,ABLIM2,SDCBP2,MEGF11,GABRG2,GALC,CPLX2,PPARGC1A,GLI2,TOX3,GNAO1,ADGRA3,GPD2,ATP2B1-AS1,GRIA2,PRDM5,GRM8,ZBTB49,ZHX1,NCKAP1L,INSYN1,RBPJ,SLC6A17,ITGAM,C2CD4C,SLC35G1,KCNH2,IPO5,STXBP5,LMO2,NCOA7,MAP4,AQP11,MATN2,MBD1,LRP1B,MEF2C,MEIS2,KITLG,AFDN,IDNK,NF1,NOVA1,DNHD1,CNTN3,PRTG,PDE4D,SLC10A4,GPR85,PIK3R1,XRN1,SMIM7,LRP12,SCHIP1,EPB41L4B,DRAM2,PPM1B,TATDN3,PRKAB2,PRKACB,PKIA,EPDR1,MAPK9,GRAMD1C,PRPH,MASP1,GDPD2,TMEM260,PTPN13,PTPRO,PTX3,TTC13,PPP2R3C,CEP97,ZNF793,FAT4,ZNF493,RASGRF2,KHDRBS2,RET,REV3L,SLC25A36,DCUN1D2,SETD5,CARF,RPE,FBXW7,MCMBP,ATP8B4,ZNF568,SALL1,SCN8A,FNIP1,ZFP2,TRA2B,KIF21A,SH3GL3,PPM1E,CNKSR2,NLGN1,ANKRD6,CCDC88A,GKAP1,RCOR3,MBD5,LMBRD1,SNRPN,GLT8D1,RBM26,LMO3,CLASP2,TROVE2,NEK4,ADHFE1,COBL,C12orf76,PJA1,CAMTA1,ADGRL3,SATB2,TRIM2,RPGRIP1L,ZFPM2,SLC44A1,CSMD1,RGMB,RUNDC3B,SGK3,RPL7L1,XRCC4,ZNF19,ZNF45,EML6,FTSJ1,CADM2,NT5M,PRDM10,HPS4,CIAPIN1,PARP11,FZD3,NHSL1,FXR1,NETO1" MicroRNA hsa-miR-3182:mirSVR_highEffct hsa-miR-3182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.66E-93 1.49E-89 3.36E-92 3.09E-91 234 1301 "VWA5B2,NCKAP5,BRAP,PLEKHH1,PWWP2A,PTCHD1,AP2A2,KCTD16,SPARCL1,SPOP,FAM135A,ZFAT,EP400,LCORL,PKP4,APC,BCAS1,TNRC6C,SHROOM2,ARNTL,INSYN2B,EIF4G3,ATP1B3,ALDH7A1,ADAM23,MPDZ,CFLAR,NAE1,KALRN,CAST,RUNX1T1,LDB2,CBFA2T2,ENTPD6,DGKI,CDH2,LRRFIP1,CACNA2D2,SRSF11,CHN1,SLIT2,CLTC,AKAP7,IQCK,COL4A5,COL9A1,SLC4A8,AHCTF1,TOGARAM2,MYRIP,ANKRD44,GDA,ARHGEF10,PHACTR3,UBXN2A,ARHGEF4,PUM1,RIMS2,PPP6R2,CCDC144A,CYBB,HDAC9,DCAF8,MATR3,DGKG,GRIN3A,NYAP1,DNAH9,DMTF1,CASP8AP2,DTNA,MAMLD1,E2F6,PHC2,FCF1,RASGRP1,FSD1L,PHF20L1,EGR3,RCAN2,LRRC17,EPHB1,GPHN,RABEPK,SRRM1,CEP85L,ETV1,MRVI1,CLVS1,FCGR1A,CEP78,CHST15,FDFT1,PRMT5,GORAB,SUCO,SEMA4D,SLC37A3,JKAMP,HVCN1,FAM49B,ATP2C1,ABLIM2,ZMAT1,MEGF11,GALNT15,RAPGEF6,NEU3,TUBGCP4,GGTA1P,GHR,MALT1,BRD8,TCERG1,ZNF638,LILRB4,PRUNE2,MCHR1,ATP2B1-AS1,GRIA2,PRDM5,ZNF496,KAT7,AP4S1,MAP4K5,FRMD3,CELF5,KTN1,PAXBP1,PACRG,MAT2A,MEST,PPM1L,MYH3,LYRM9,NEK1,NFE2L2,CNOT4,OGG1,OPA1,CDK18,JAKMIP1,PRKACB,EPDR1,FITM2,GRAMD1C,DIRAS2,DCHS2,RELN,PTCH1,MTMR10,ELOVL2,EML5,STRC,MARCH1,RBBP8,ZDHHC14,DUSP15,RIC8B,ZFHX4,TMLHE,ALG9,CARF,ELP2,CCDC102B,ZNF331,SCN8A,CASC3,SUPT20H,ZFP30,FBXO11,CPEB4,ANKRD36,MBD5,NMNAT2,KDM4C,RBM26,ZNF302,ELOVL4,ADHFE1,KLHL7,ARHGEF9,ANKRD28,ANKRD12,EXOC7,TBCEL,FBXW11,ATMIN,TCF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,FAM200B,ITGB3BP,SLC44A1,TIMP4,ASXL3,BHLHB9,ERCC6L2,TPM1,ZNF346,SGK3,UGT8,PLEKHH2,P2RY12,ZNF781,RICTOR,GUSBP1,CFAP298,KCNT2,ATP6V0E2,TCEAL7,ZNF213,UPF3A,EMSY,STOX2,RNF103,KCNAB1,PDSS2,FZD3,MARCH8,KAT6A,CASC15,TRAM2-AS1,ZDHHC20,FRMD6,DPF3,JPH3" MicroRNA hsa-miR-135a:mirSVR_lowEffct hsa-miR-135a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.76E-93 2.11E-89 4.74E-92 4.37E-91 283 1892 "NCKAP5,SYS1,FMNL2,KLHL32,TMEM132B,GALNT16,ADD1,ADD2,PWWP2A,BEND6,OLMALINC,HACE1,OSBPL8,SEMA6A,ARHGAP20,UNC79,ZFAT,CDC42BPA,EP400,SUGT1P4-STRA6LP-CCDC180,APBA2,PRX,NCOA1,ATP2B2,ZNF582,ZNF583,DPY19L3,LINC00847,HCN2,SYNJ2,MTMR2,GYG2,CFAP410,VXN,NFS1,METTL6,P2RX6,CD86,ZBED1,LRRFIP1,MAGI1,CDO1,CCPG1,FOXN3,NDST3,CPNE6,CLCN3,RAB26,CNGA3,IQCK,PCYT1B,AKAP6,SLC4A8,ABI3BP,MYRIP,ZNF385A,SLC35F1,RNF14,NCOR1,GDA,SNCAIP,CSF1,PPP1R16B,PHF14,GREB1,ARHGEF4,RIMS2,DOCK4,KATNAL2,GAPVD1,RIPOR2,DCAF8,DBI,ARMCX4,RUSC2,C2CD2L,RHOBTB1,SACS,SV2B,WDR20,DYNC1I1,DOCK2,DMTF1,SLC12A6,DPH1,CASP8AP2,SLC25A18,ACOT8,DRP2,DTNA,FAM78B,WDPCP,EDN1,FCF1,MRO,KMT5B,AASS,COPS4,RGS17,DCTN4,EIF1,EPB41,APC2,VPS26C,DNAJC27,SIRPB1,EXTL2,CEP78,FCGR3A,GORAB,FER,AMOTL2,IP6K2,RGPD5,FLT1,SYT3,C2orf88,MEGF11,HRASLS5,CHL1,GABRG1,GAD1,B4GALNT1,RAPGEF6,ZNF274,DISC1,CPLX1,CYP46A1,LYVE1,RNPS1,HPGDS,DBF4,TOX3,STARD3,ZNF638,DCLK2,LNX1,ADGRA3,LILRB4,PRUNE2,PCLO,GRIA2,BTN2A1,BVES,ADAMTS6,MAP4K5,RASSF8,ZHX1,INSYN1,MIER3,NEGR1,AGFG1,SHISA6,MSL1,GAREM2,RBPJ,LRRCC1,KCNB1,KIFC3,KIT,CYP27C1,KTN1,HECTD2,MAP4,MARK1,MAT2A,MATN3,MEF2C,MEIS2,MEST,KCTD6,MID1,PPM1L,POC1B,MN1,MOV10,SAMD5,HS6ST3,NF1,ALDH1L2,DNHD1,NUCB2,GPR137C,PRTG,GPR85,PIK3C2A,ZNF655,CCSER2,SNX10,GPSM2,ANKRD16,KANSL1,CEP41,SNRK,WDR25,CNTLN,BDNF-AS,PTPRE,SH3TC2,OXR1,RASGRF2,RBBP6,MSANTD2,REV3L,PRIMA1,RIC8B,SETD5,GSTCD,ROBO2,SPIN3,ZNF671,MCMBP,ATP8B4,GLDN,TCP11L1,SEMA6D,SCN2B,SCP2,MRAS,SUPT20H,FAM102A,HKDC1,NLGN1,DZIP1,FAM81A,KBTBD4,ELMO2,ATF7IP,SMARCA4,RCOR3,MAPKBP1,USP33,TRERF1,NMNAT2,GLT8D1,TEX2,DBNDD2,IQSEC2,ATP10B,ZC4H2,CEP68,JMJD6,PRRC2C,VPS13A,PLCB1,COBL,CAMTA1,DNMBP,TCF4,ZEB1,PCDHA5,DICER1-AS1,ZFPM2,GPR161,TIAM1,MTMR14,TNS1,TPM1,NEIL2,STXBP4,RUSC1,UBE2H,OSBP2,PLEKHH2,ZNF28,ZNF154,EML6,SPIRE1,SMARCAD1,SLC38A1,ADAMTS9,HPS4,FAM47E,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,CASC15,ACTR3B,TRAM2-AS1,MSRB3,SOCS4" MicroRNA hsa-miR-182-5p:TargetScan hsa-miR-182-5p TargetScan 4.93E-93 2.76E-89 6.20E-92 5.71E-91 202 963 "AS3MT,ADCY6,KIAA1211,PTCHD1,HECW2,KLHL13,KCTD16,KIAA1324,ABCD2,PCDH10,GPRASP2,PDZD4,OGT,CDC42BPA,LRCH2,PHF12,APBA2,ARHGDIA,MARCH3,NUMB,ATP1B3,DPY19L3,DOCK11,BMPR1B,DST,JAZF1,CACNA1B,CACNA2D1,CACNB4,PRC1,EVI5L,MAGI1,DLGAP2,CACNA2D2,FOXN3,QKI,CNGA3,CNN3,CNR1,CNTN1,RTTN,BAG4,MYRIP,IGDCC3,CLOCK,PREPL,C2CD2,ANKRD44,AATK,APPL1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,KIF26A,GIT2,DNAL1,JAKMIP2,ELMO1,RHOBTB1,KIF19,DYNC1I1,EBF1,EDNRB,FEM1B,FAM13A,PHF20L1,MBNL2,EGR3,EIF5,RGS17,C8orf37,PAN3,EPHB1,GPHN,RAB9B,ERBB4,NCALD,CEP85L,NRN1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,CELF1,NSG1,FUT9,GABBR1,CHL1,B4GALNT1,RAPGEF6,KDM2B,PRUNE2,GRIK4,KAT7,FAM107A,ATOH8,HAS2,FRMD5,BACH2,C2orf72,CDH20,KCNJ5,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,PIK3AP1,CHIC1,LRP1B,MEF2C,MEIS2,PPM1L,MITF,MMP16,ADAM22,MYO9A,NF1,NOVA2,NPTX1,NPTX2,NRCAM,OCRL,CHAMP1,PAX6,PCDH8,PCSK5,CDK18,PDE4D,GPR173,GPR85,PIK3R1,FAM216A,PLCL1,PCDH18,LRP12,MAGEL2,EPB41L4B,PPP3CA,PRKACB,CEP41,CNNM2,EML5,PTPRG,PTPRN2,MARCH1,RDX,FIGN,ALG9,FBXW7,MCMBP,CSRNP3,ATXN7,SCN8A,MRAS,CCDC92,CCDC88A,ATF7IP,LIMCH1,FAM126B,PDZD2,FNBP1,ERC1,PEG10,IQSEC2,NFASC,CLSTN2,NXT2,PHLDB1,KLHL7,FBXW11,SATB2,DOCK9,NSD1,CRTC1,GPRIN3,DICER1,ASXL3,RIMBP2,RUNDC3B,PPIL6,DCBLD1,BCL2L13,RICTOR,REEP1,CADM2,EVI5,CIAPIN1,RGS7BP,AMN1,FZD3,RTN4,JMJD1C,FXR1,GAN" MicroRNA hsa-miR-1:mirSVR_lowEffct hsa-miR-1:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.94E-93 2.76E-89 6.20E-92 5.71E-91 275 1793 "SYN3,CLK4,EMILIN3,FMNL2,KLHL32,OLMALINC,INTS2,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,HFM1,SEMA6A,PCDH10,UNC79,FAM135A,SYT13,ZNF687,AMPD3,AMPH,AMT,CDC42BPA,LRCH2,VAT1L,TNRC6C,LGR5,PPP4R4,CASK,TMEFF1,ARNTL,CHRD,DYNLL1,RNF182,ATP6V0A1,TTLL9,ADGRB3,BCL7A,SYNJ2,ARHGEF7,SCAPER,GYG2,SGCE,C5,WASF1,MYRF,CA12,CACNA1A,CALB1,PTBP2,PRC1,METTL6,P2RX6,ENTPD6,CDH2,SRSF11,FBXO7,QKI,LETMD1,AKAP5,TBPL1,SMARCAL1,CNRIP1,CLOCK,C2CD2,CRHBP,AKAP12,ANKRD44,CSF1R,CNTNAP2,SLITRK5,KIAA0040,PHF14,RIMS2,GPSM1,HDAC4,ZNF337,TBC1D5,AIF1L,PITPNC1,ZBTB24,MYEF2,KIAA0319,SPOCK3,FAM107B,KIF19,DMPK,USP3,CDON,GOLT1B,EBF1,EDIL3,HEYL,KLHL5,TMTC1,YAF2,KCTD3,EIF4G2,EIF5,PLEKHA1,RGS17,EMX2,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,CLVS1,FAM198B,RPS6KC1,SH3YL1,PTK2B,TAOK3,FCGR1A,ZNF589,FGF14,BAIAP2,RGPD5,SLC37A3,FLYWCH1,PDLIM5,KHDRBS3,DLL3,GALNT15,ZNF274,DISC1,ACSS1,CPLX2,IGSF5,TUBGCP4,MSTN,CYP46A1,TOX3,KDM2B,GNG4,FUT10,TMEM121B,GRIA2,PRDM5,BTN2A1,GSTM5,ADAMTS6,IRAK3,UBE2QL1,BACH2,ELOVL5,ACOT7,HNMT,LRRC75A,SMAP1,IRF8,IDH3A,FAM95B1,KNDC1,LRRCC1,IL6ST,INPP5B,ITPKB,LIFR,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,KITLG,AFF1,GIT1,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM2,ALDH1L2,VWA2,NTRK2,ZNF827,GLIPR1L2,PAX6,PRTG,GPR85,FAM218A,EPB41L4B,PPP2R2B,PPP2R5E,WBP1L,CNTLN,PTPRN,ZNF793,FAT4,ZDHHC14,REV3L,RGS3,RIC8B,ZFHX4,CYB561D1,NEK11,ZNF671,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,ATXN2,LRFN5,GALNT10,SUPT20H,SGK1,KIF16B,CHD9,FBXO11,ST6GAL1,SYBU,NUBPL,SLC6A8,SLC9A5,SLC12A2,ZFP1,SMARCA4,SMARCC2,LIMCH1,MAPKBP1,TMCC1,FAM126B,DOP1A,NMNAT2,HECW1,NFASC,MPRIP,ELOVL4,SEPT3,SUPT5H,SYNE2,SYN1,C12orf76,TAL1,AGTPBP1,SATB2,SYNE1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,CCDC173,ZFPM2,AP4E1,TK2,ACTR6,BEX4,RIMBP2,CSMD1,PIK3R5,ANKRD20A2,TTTY15,RPRM,VSNL1,WIPF1,RICTOR,ZIC1,ZNF711,MKRN3,ZBTB38,ANKS1B,UPF3A,FIP1L1,ST7,KAT6A,HNRNPA3,FXR1,NETO1,ST8SIA2,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-3164:mirSVR_lowEffct hsa-miR-3164:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.33E-93 2.98E-89 6.67E-92 6.14E-91 261 1621 "KCNH8,SYS1,ADCY6,ADD1,PLEKHH1,PWWP2A,INTS2,MTUS1,HACE1,TBC1D14,SPARCL1,ALCAM,BBOX1,FAM135A,PDZD4,SUGT1P4-STRA6LP-CCDC180,EPB41L5,VAT1L,USP37,SHROOM2,CASK,ZSCAN18,ZBTB10,RNF182,ADGRB3,BBS2,MIR9-3HG,BID,RAB29,MYRF,CFAP410,CACNB4,KALRN,CAST,KYAT1,SLC16A4,P2RX6,CBFA2T2,LARGE1,DLGAP1,CACNA2D2,B4GALT6,TPP1,FBXO7,CNN3,AKAP7,PCYT1B,ARMC8,COL4A5,ABI3BP,RBM39,CSNK1G3,IPCEF1,VAC14-AS1,CNTNAP2,DZIP3,PHF14,GAPVD1,DCAF8,ZNF337,KIAA0586,AIF1L,ARMCX2,MFAP3L,C2CD2L,KLHL3,RHOBTB1,SV2B,CHRDL1,DMD,USP3,DOCK2,DMTF1,DPYSL2,ARRDC4,MAMLD1,EDN1,EDNRA,ANKRD46,CNNM1,PHF20L1,KMT5B,EIF4G2,EIF5,VPS13B,LRRC17,MTSS1L,TUBA1B,PRAM1,CHST15,PPP1R1B,ZNF589,FOXF2,SYNCRIP,EVL,FLT1,STAU2,OGA,CHL1,FAM120B,DISC1,SRRM4,GATM,GCNT2,PCDH17,GLUL,WDFY3-AS2,LILRB4,PRUNE2,STON1,GRIA2,CLASRP,ZBTB49,RABL2A,PSIP1,RNFT2,IRAK3,HMGCL,AGBL5,IGFBPL1,AGFG1,MYLK2,IGF1,TJAP1,ITGAM,KCNJ16,A1BG-AS1,CYP27C1,LIFR,LIG4,SFXN5,LIMS1,NCOA7,MAP2,MARK1,MBP,ADAM11,CHIC1,LRP1B,MGAT3,MIA2,MID1,PPM1L,COL28A1,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,HNRNPM,NFIX,DNHD1,P2RX7,P2RY1,CNTN3,ETFRF1,PDE4D,CCSER2,XRN1,GPSM2,MAPKAP1,SCHIP1,ING3,POLR2F,DRAM2,PPM1B,PPP2R2C,KANSL1,PPP5C,PRKCB,SLC26A11,DIRAS2,WDR25,ELOVL2,PTPRB,PTPRE,TTC13,STRC,TMEM231,ACSS3,FAM66C,RASGRF2,RBBP6,RET,RIC8B,SETD5,CARF,PNMA8A,CYB561D1,ROBO1,CCDC102B,BAALC,ZNF671,GLDN,CLIP1,ZNF331,SEMA6D,ATXN2,PRCD,SMPD3,ZNF821,CHD9,DZIP1,ANKRD6,ARHGEF40,GKAP1,CDK5RAP2,LIMCH1,MBD5,ANKFN1,ZNF415,KDM4B,DOP1A,TRERF1,SP4,RBM26,ZNF621,ATP10B,CLASP2,CLSTN2,KANK1,STXBP1,NECAB1,ARHGEF9,COBL,TACC1,TAL1,FAM208A,SIN3B,ZFP90,TPCN2,OBSL1,SIK3,AP4E1,CDH22,NR2E1,KAT6B,C9orf85,TRIO,AMACR,SSBP2,LINC00689,WIPF1,GUSBP1,KCNT2,TRIM9,LYPD6,FSTL5,ZSCAN26,SPIRE1,ZFAND5,ZXDA,LINC02210,FIP1L1,MPPE1,PDSS2,DNAH10,MRPL47,DOCK8,FAM219B,TIGD6" MicroRNA hsa-miR-412:mirSVR_lowEffct hsa-miR-412:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.99E-93 3.35E-89 7.48E-92 6.89E-91 276 1807 "DGCR6,KCNH8,ABHD6,FMNL2,TMCC3,ADD2,PTCHD1,AP2A2,FAM135A,SYT13,ZFAT,ANK2,PI16,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PPFIA3,SHROOM2,CDC14B,ARNTL,SLC2A11,BBS2,KSR1,FUBP1,RAB29,CA12,CACNA1B,CALM1,PTBP2,CAST,RUNX1T1,MTMR7,CBFA2T2,SCARB1,C1orf52,SEPT7,ARHGAP33,LRRFIP1,CHN1,CHN2,RAB33A,NRXN3,DGCR9,AKAP7,AKAP6,COL9A1,COL9A3,COL11A2,SLC4A8,ZFP28,FAM171B,RNF14,ANKRD44,PDE4DIP,SLITRK5,GREB1,RUBCN,DOCK4,GAPVD1,TCAF1,RIPOR2,RASSF2,KIAA0586,TMEM170A,SCRN1,SPATA2,ELMSAN1,MFAP3L,RUSC2,ZC3H11A,GSDME,WDR20,ZNF582-AS1,DMD,DOCK2,ACOT8,ARRDC4,E2F5,ANKRD46,HIPK3,PHF20L1,APH1A,AASS,KCTD3,COPS4,TNK2,PCOLCE2,HSD17B14,EPB41,RCAN2,ANKMY1,RPS6KC1,TAOK3,CORO2B,DLC1,ST3GAL6,GTF2IRD2,FLT1,EFCAB2,WDR83,NBEA,POMT1,STAU2,HHIPL1,TRAF3IP2,IP6K3,SIGLEC8,MTHFD2,C15orf41,INPP5K,KIAA1841,GATM,ALDH1L1,ADAM28,GGT7,CRCP,DBF4,SPIN1,MSL3,LUZP2,DCLK2,GNAO1,CCDC184,PCLO,STMN2,GRB10,GRIA2,PLCD4,ADAMTS13,GRM2,AP4S1,FAM222A,HAS2,PACSIN2,CPT1C,CELF5,MSL1,IDH3B,SCIN,ZNF678,INPP5B,NME9,ITGAM,KLHL23,LIFR,HECTD2,MAP4,MAP6,MARK1,MBD1,PPM1L,AFDN,ZNF680,SAMD5,N6AMT1,CCDC13,NEK1,NOVA1,NTRK2,NTRK3,ZNF713,P2RX7,ZNF827,PDE4B,PDE4D,FAM216A,SMIM7,PURG,PRIMPOL,ANKRD16,STRN3,PPM1B,VSTM2L,PRKACB,MAPK9,VPS13C,WBP1L,SNRK,TMEM104,CNTLN,PTPRH,ZSCAN2,TMEM231,RAD17,SH3TC2,TRIM68,ERI2,RGS12,RNASE1,CCDC82,ARMC5,CARF,CCDC25,NEK11,TCP11L1,ABCA11P,SATB1,SCN8A,SCP2,TNFRSF19,ZNF821,GALNT10,MRAS,SH3BGR,SH3GL3,HKDC1,FBXO11,FNDC3A,NUBPL,PEX26,PPP4R3A,DHX30,KANSL3,SLC8A1,SLC22A4,ARFGAP1,OGDHL,SMARCD3,RCOR3,SNAP25,MAPKBP1,MYCBP2,ERC1,PEG10,DDN,ATP10B,CAMTA2,ITPRID2,SST,SSTR1,SSPO,ERBIN,ELOVL4,SEPT8,RGL1,ADHFE1,KANK1,STXBP1,SYN2,TACC1,EXOC7,TRIM2,RPGRIP1L,SYNE1,DOCK9,TNS2,CYB561A3,SIRT1,AP4E1,SLC44A1,NR2E1,TMPO,FAM124A,C9orf85,TSN,SSBP2,UBE2H,UBE3A,UCHL1,FLRT2,CCDC14,WIPF1,P2RY12,AGMO,NDRG4,MKRN3,ZNF138,EML6,MAP3K12,DNALI1,RNF103,FIP1L1,PARP11,FAM219B,ADAMTSL3,MSRB3,ST8SIA2" MicroRNA hsa-miR-3172:mirSVR_lowEffct hsa-miR-3172:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.84E-93 3.83E-89 8.52E-92 7.84E-91 276 1808 "EMILIN3,ADD2,ESYT2,KLHL13,RTL9,ALCAM,DOC2A,ANK2,CCDC146,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,AQP6,PPP4R4,ZFYVE28,CDK13,MARK4,NUMB,EIF4G3,STX16,SLC2A11,RNF182,ALDH7A1,ADGRB1,ADGRB3,BCHE,RGS11,NRP2,KSR1,BMP7,ARHGEF7,BTK,RAB29,CA8,CACNB4,CALM1,KALRN,VXN,CAST,RUNX1T1,DGKI,LRBA,SEPT7,ZBED1,DIS3L,EPS15L1,TPP1,SULT4A1,IGLON5,ARHGEF6,CNR1,COL4A5,SUMF2,LETMD1,SLC4A8,ABI3BP,ENTPD4,SH2B1,AKAP12,ANKRD44,CLIP3,ABCG1,RGS6,ARHGEF10,PDE4DIP,GREB1,RIMS2,GPSM1,DOCK4,KATNAL2,TCAF1,CENPL,TBC1D5,MATR3,MAML1,BRINP1,ZBTB24,HEPH,ELMO1,KIAA0753,ZC3H11A,POM121,RHOBTB1,PLPPR4,WDR20,KIF19,CHRDL1,DMTF1,SLC25A18,DTNB,MAMLD1,SNX29,FCF1,CNNM1,STARD3NL,EPHB1,MRPL37,TLR7,RASL12,SIRPB1,ABCA8,CHST15,GORAB,GTF2IRD2,FGF11,FGF13,POLK,UBE2E3,PCYOX1,FLT1,NOP56,FLYWCH1,EFCAB2,PDLIM5,FAM49B,STAMBP,ATP2C1,ZNF605,ABLIM2,GABRA3,FAM120B,ZNF234,DISC1,GCK,GCNT2,SULT1C4,ADAM28,MALT1,ZNF276,SPIN1,KDM2B,KCNMB4,ZNF782,GRB10,GRIA2,ADAMTS13,GRIN2D,BVES,RABL2A,RNFT2,ADAMTS6,SLC2A6,MUM1,ZHX1,HNF4G,ZNF546,SCIN,ITPKB,METTL21A,KCNJ5,GATD1,KIF5A,CYP27C1,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,NCOA7,GPR155,MBNL1,CHST6,SCAMP5,POC1B,XRRA1,MMP16,HS6ST3,RTL5,NF1,NPTX1,NRCAM,LOC100128398,OLA1,DUSP26,GPSM2,ANKRD16,ING3,POLR2F,PPP2R2B,RASGEF1B,SLC26A11,CNNM2,PTPRG,ZNF615,PPP2R3C,PID1,CCDC40,SH3TC2,ZDHHC4,UBR7,RIC8B,CCDC82,ALG9,PNMA8A,ROBO1,ROBO2,SNX22,ATP8B4,SGSM1,PTGR2,MAPK12,ATXN2,SCN2B,PRCD,SEC14L1,GALNT10,KIF16B,FNDC3A,SEC31A,NUBPL,PEX26,BTBD3,KANSL3,SIRT2,ATF7IP,SLC22A4,MAST1,CDK5RAP2,SNRPN,ZSWIM8,HECW1,PEG10,ZBTB43,ATP10B,CLASP2,ITPRID2,SSTR2,CEP68,STAC2,ADHFE1,PHLDB1,KANK1,KLHL7,ARHGEF9,ANKRD28,EXOC7,TAL1,KLHL4,DMXL2,ZFP90,TRIM2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,SIK3,ZFPM2,TIAM1,PRRT1,CDK20,WBP2,CHST5,ZNF346,METTL3,PPIL6,SGK3,SLC35A4,VIPR2,VSNL1,ZIC2,TCEAL7,ANKS1B,LAMP5,PRDM10,ADAMTS9,SLC17A7,FZD3,HNRNPA3,IFT88,NETO1,ST8SIA2" MicroRNA hsa-miR-744*:mirSVR_lowEffct hsa-miR-744*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.19E-93 4.02E-89 8.93E-92 8.23E-91 260 1611 "TMEM132B,GALNT13,ADORA1,USP31,BEND6,KIAA1324,CC2D2A,HFM1,C1QTNF3,FAM135A,PDZD4,PITPNM2,LRCH2,PHF12,PKP4,APBB2,UPRT,LGR5,PLA2G4C,ARSE,NUMB,SLC2A11,N4BP2L1,DPY19L3,GPR146,SYNJ2,ARHGEF7,CASTOR3,RAB29,IL33,CABP7,THSD7A,SPAG9,LDB2,METTL6,CCNH,CLGN,NUMBL,MS4A7,RAB33A,NRXN3,QKI,IQCK,AKAP6,SUMF2,ABI3BP,ZFP28,PREPL,HAPLN1,GDA,ABCG1,SNCAIP,IPCEF1,SOCS5,PHACTR3,KIAA0040,UBXN2A,CTH,GREB1,PUM1,RIMS2,CCDC144A,ARHGAP32,TCAF1,CENPL,TBC1D5,KIAA0586,KCTD8,ZBTB24,KIAA0753,SV2B,EXOG,DNAH9,DMTF1,CASP8AP2,ARRDC4,GOLT1B,WDPCP,EDN1,EDNRB,HIPK3,KLHL5,PHF20L1,SUGP2,KMT5B,EGR3,EIF4G2,ELN,EPB41,EXTL2,NSRP1,RPS6KC1,TBC1D16,TMEM132C,PTK2B,ZNF589,SLC9B2,GTF2IRD2,SUCO,IQCG,ATP13A4,FLT1,TMEM107,MPP6,ERAP1,MTHFD2,ACSS1,TUBGCP4,GFRA2,LYVE1,TOX3,STMN2,GRIA2,PLCD4,GRIN2C,AP4S1,FAM107A,MAP4K5,HLF,HNMT,ZNF491,SMAP1,FAM95B1,ZNF546,LRRCC1,SCIN,INPP5B,ITPKB,CDH20,KCNB1,KCND1,CYP27C1,LAMP2,PAXBP1,LMO2,MBNL1,MEIS2,MIA2,KITLG,SCAMP5,N6AMT1,NEXMIF,NDP,NFE2L2,VWA2,NOVA1,DNHD1,SMIM11A,OXTR,PCDH9,PCSK1,GPR85,ZNF655,ZFYVE21,LRP12,SH3KBP1,PPARA,CCDC144B,LRRN3,PPP3CA,PRKAB2,WBP1L,LAMA1,PTPRB,PTPRD,PTPRH,PTPRO,ACSM5,TUG1,ZNF793,FAT4,OXR1,KHDRBS2,ERI2,PBRM1,TMLHE,ARMH4,FBXW7,KIAA0895L,ADAL,MEG3,ABCA11P,SALL1,SCN2B,SCN8A,FNIP1,TRA2B,ZFP30,AMBRA1,ST6GAL1,ANKRD6,ZNF430,SLC9A5,BTBD7,ZFP1,ANKRD36,SNAP25,KDM4B,PDZD2,FNBP1,HECW1,KDM4C,TSPYL2,RBM26,POGZ,ELOVL4,SULF2,SYNE2,ARHGEF9,SYP,TAL1,TBCEL,SLC19A3,OBSL1,CYB561A3,FAM200B,ITGB3BP,ARL10,TP53BP1,TPM1,ZNF346,ELP5,PDSS1,NEIL2,STXBP4,SGK3,RPRM,SLC35A4,BCL2L13,VLDLR,VSNL1,RBFOX3,LAT2,RICTOR,ZIC2,ZNF24,ZNF28,TRIM9,ZNF177,ANKS1B,SPIRE1,ZNF213,PRDM8,HPS4,SIGLEC10,SLC17A7,PDSS2,RGS7BP,DNAH10,FAM13C,FZD3,SMIM8,TMEM63C,FBXO36,TIGD6,MSRB3,NHSL1,FRMD6,LAS1L,SENP7" MicroRNA hsa-miR-92a:mirSVR_lowEffct hsa-miR-92a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.56E-93 4.23E-89 9.38E-92 8.63E-91 264 1660 "VWA5B2,AS3MT,ELFN2,CCDC85A,PWWP2A,BEND6,MTA3,HACE1,OSBPL8,AK2,PCDH10,UNC79,AMPH,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB2,MAGEE2,DDO,PPP4R4,CASK,RGS20,CDK13,ZBTB10,NCOA1,SLC4A4,ATP1B3,DOCK11,BACH1,RGS9,FUBP1,SLC16A4,L3MBTL4,DLGAP2,CLGN,PLAA,NGEF,LY86,AKAP7,PCYT1B,ARMC8,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,WDR20,NR1D2,MAMLD1,EDIL3,FAM13A,PHF20L1,EIF4G2,TENM1,STARD3NL,EIF1,EMX2,EPB41L2,ERBB4,MRPL37,DNAJC27,CLVS1,SCML2,DLC1,RACK1,ST3GAL6,FKTN,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF10,GABBR1,MTHFD2,LRRC37A6P,KIAA1841,GATM,DBF4,ZNF638,PRRC2B,FUT10,GRM8,GSTT2,SOX21,GUCY1B1,ZHX1,HMGCR,LRRC75A,EID2B,INSM1,JAK2,METTL21A,KCND2,IPO5,PAXBP1,HECTD2,NCOA7,PACRG,MAP4,MARK3,TM6SF1,MEIS1,AFF1,MMP16,MYH3,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PFKFB4,PIK3C2A,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,PPARA,PPM1B,PPP2R5E,NKAIN4,RANBP3L,PRKAB2,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,ANKHD1,PTPRG,STRC,MARCH1,SLC25A48,USP47,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,RET,GTDC1,SLC25A36,ZFHX4,EXD2,C12orf49,STK32B,LRRK2,RPS20,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,ATXN7,RASA3,SGK1,FERMT1,SHC4,FBXO11,SYBU,FAM81A,SEPHS1,ATF7IP,SMARCC2,LMBRD1,SNRPN,SOX11,DOK5,HECW1,TSPYL2,MCF2L2,RBM26,ZC4H2,SS18,ERBIN,ZSCAN29,SEPT8,DIP2A,STXBP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,KLHL4,ATMIN,DMXL2,ZEB1,NAT16,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,CSMD1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,PLEKHH2,XRCC4,ZNF28,ELFN1,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,SENP7" MicroRNA hsa-miR-19a*:mirSVR_highEffct hsa-miR-19a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.89E-93 4.42E-89 9.77E-92 9.00E-91 231 1274 "KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,VAT1L,PPP4R4,SPTBN4,NUMB,EIF4G3,BACH1,BCL7A,MTMR2,SGCE,IL33,CACNA1B,CALM1,KALRN,PTBP2,CAST,LRRFIP1,NOG,CFL2,CBARP,SOCS6,NRXN3,PPT2,FBXO7,FAM189A2,C4orf33,ARMC8,RCHY1,MYRIP,IGDCC3,SLC35F1,FAM171B,CLOCK,SUSD5,PLXNA4,PHF14,CTH,USP6NL,ARHGAP32,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,ARMCX4,RHOBTB1,FAM107B,DMD,CPEB2,DTNA,EDN1,EDNRB,RASGRP1,KLHL5,PHF20L1,EGFR,EIF4G2,EMX2,LRRC17,CEP85L,CDKL3,TLR7,ADGRV1,TAOK3,DLC1,FDFT1,POLK,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,ATP2C1,CELF1,MEGF10,CHL1,GABRB3,MTHFD2,GATM,NEU3,ARFIP1,AHDC1,GLI2,TOX3,ZNF638,GNAO1,FERMT2,GRB10,SOX21,RASSF8,FRMD3,ARHGAP36,NEGR1,SHISA6,LRRCC1,KCND2,STXBP5,TTYH2,PAXBP1,ASPRV1,PIK3AP1,MARK1,MATN2,EFHB,MEIS1,KCTD6,MIA2,PPM1L,MITF,ZNF680,MYO9A,NFE2L2,SMIM11A,OGG1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,SLC10A4,GNG2,FAM218A,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,CCDC144B,PRKCB,MAPK10,HYDIN,ELOVL2,PTK2,PTN,STK32A,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,SPIN3,MCMBP,LRRK2,ABCA11P,HSD11B1L,RTN1,SATB1,ATXN7,SCN7A,SCN8A,FNIP1,KIF21A,CPEB3,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,KDM3A,SP4,ZC3H13,ITPRID2,ZC4H2,NXT2,RGL1,VPS13A,SYT1,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,SYNE1,PCDHB9,OBSL1,PUM2,NR2E1,TMPO,R3HDM1,C9orf85,SYNPO2,TRO,ANKRD20A2,PRR18,TUBB1,RPL7L1,FAM155A,BCL2L13,P2RY12,GUSBP1,XPO1,XRCC4,CFAP298,ZIC2,ZNF28,KCNT2,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,SPIRE1,TMEM178A,NAV3,PDSS2,FZD3,KLHDC1,DPF3,JPH3" MicroRNA hsa-miR-613:mirSVR_lowEffct hsa-miR-613:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.24E-93 4.61E-89 1.02E-91 9.37E-91 277 1822 "SYN3,CLK4,EMILIN3,FMNL2,KLHL32,TMEM132B,ADD1,OLMALINC,INTS2,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,SEMA6A,PCDH10,UNC79,FAM135A,AMPD3,AMPH,AMT,CDC42BPA,LRCH2,VAT1L,LGR5,PPP4R4,CASK,TMEFF1,ARNTL,CHRD,DYNLL1,EIF4G3,RNF182,ATP6V0A1,TTLL9,ADGRB3,MIR9-3HG,BCL7A,KSR1,SYNJ2,SCAPER,GYG2,SGCE,C5,WASF1,CA12,CACNA1A,CALB1,PTBP2,RUNX1T1,PRC1,METTL6,ENTPD6,SRSF11,QKI,COL4A5,LETMD1,AKAP5,TBPL1,SMARCAL1,CLOCK,C2CD2,CRHBP,AKAP12,ANKRD44,CSF1R,CNTNAP2,SLITRK5,KIAA0040,PHF14,RIMS2,GPSM1,HDAC4,TBC1D5,AIF1L,MYEF2,KIAA0319,SPOCK3,FAM107B,KIF19,DMPK,USP3,CDON,GOLT1B,EBF1,EDIL3,HEYL,KLHL5,TMTC1,KCTD3,EIF4G2,EIF5,TENM1,PLEKHA1,RGS17,TMEM35A,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,MRVI1,CLVS1,FAM198B,RPS6KC1,SH3YL1,PTK2B,TAOK3,FCGR1A,ZNF589,FGF11,FGF14,BAIAP2,SUCO,SLC37A3,PDLIM5,TPK1,KHDRBS3,DLL3,GALNT15,ZNF274,DISC1,CPLX2,IGSF5,MSTN,MALT1,TOX3,KDM2B,FUT10,GRIA2,PRDM5,GSTM5,IRAK3,RASSF8,UBE2QL1,BACH2,ELOVL5,ACOT7,HNMT,LRRC75A,SMAP1,IRF8,IDH3A,FAM95B1,KNDC1,LRRCC1,IL6ST,ZNF678,INPP5B,ITPKB,LIFR,PAXBP1,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,GIT1,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM2,ALDH1L2,VWA2,NTRK2,ZNF827,GLIPR1L2,PAX6,PRTG,GPR85,FAM218A,GPSM2,PMP22,RETREG2,EPB41L4B,PPP2R2B,BCAS3,WBP1L,WDR25,CNTLN,PTPRN,ZNF793,FAT4,SUSD4,ZDHHC14,REV3L,RGS3,RIC8B,ZFHX4,CYB561D1,RORB,NEK11,ZNF671,TCP11L1,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,ATXN2,GALNT10,SUPT20H,SGK1,KIF16B,CHD9,FBXO11,SYBU,NUBPL,PPP4R3A,SLC6A8,SLC9A5,SLC12A2,ATF7IP,ZFP1,SMARCA4,SMARCC2,MYH15,LIMCH1,MAPKBP1,TMCC1,DOP1A,BDP1,FNBP1,CDK19,NFASC,MPRIP,ELOVL4,CEP68,SEPT3,SUPT5H,SYNE2,SYN1,C12orf76,TAL1,AGTPBP1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,CCDC173,ZFPM2,AP4E1,TK2,ACTR6,BEX4,RIMBP2,CSMD1,KAT6B,PIK3R5,RUNDC3B,STXBP4,ANKRD20A2,TTTY15,RPRM,VLDLR,VSNL1,WIPF1,RICTOR,ZIC1,ZNF711,ZNF24,MKRN3,ZBTB38,ANKS1B,UPF3A,STOX2,FIP1L1,ST7,KAT6A,HNRNPA3,NETO1,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-500:mirSVR_highEffct hsa-miR-500:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-92 5.74E-89 1.27E-91 1.16E-90 233 1298 "ACADM,CLK4,NCKAP5,GALNT13,PLEKHH1,BEND6,PCDH19,ABCD2,ARHGAP20,EPB41L5,ZFYVE28,ARNTL,CADPS,MARK4,PCDHGB4,SLC4A4,ALDH7A1,RIPK1,BACH1,CFLAR,KSR1,SYNJ2,ARHGEF7,FUBP1,IL33,CA8,LURAP1,KALRN,PTBP2,MTMR7,C1orf52,DGKI,DCLK1,COPB2,NDST3,IGLON5,IQCK,AKAP6,SLC4A8,BAG4,MYRIP,CNRIP1,RNF14,CS,SIPA1L1,UBXN2A,RIMS2,HDAC9,RIPOR2,ZFYVE16,DDX46,DNM1,HS3ST2,DMTF1,CASP8AP2,ACOT8,PDCD6IP,GOLT1B,E2F5,WDPCP,FCF1,SEMA3D,PCOLCE2,EYA1,FAM198B,DLC1,ST3GAL6,FGF12,PRKAG2,POLK,ATP13A4,FLT1,C2orf88,APOPT1,ATP6V1H,STAU2,ZMAT1,GABRB3,GABRG2,DENND2A,ZNF274,MTHFD2,C15orf41,DISC1,KIAA1841,MSTN,MMADHC,MALT1,KDM2B,GPR12,COQ10A,AP4S1,HAS2,MIER3,HMGCR,IGFBPL1,USP51,SHISA6,ICA1,ZNF181,SLC35G1,METTL21A,KCNH2,KCNJ16,MAP4,MARK1,MATN2,MBNL1,LRP1B,BLOC1S2,ZNF862,NFE2L2,NINJ2,NUCB2,OPA1,PCDHGC3,PDE3A,PDE4D,GPR85,NALCN,CCSER2,SNX10,XRN1,SMOX,PURG,PRIMPOL,STRN3,ING3,PPP2R5E,PRKACB,EPDR1,MAPK9,GRAMD1C,HYDIN,CNTLN,TMEM145,PEX2,ZNF844,CEP97,FAM66C,OXR1,RDX,ZMAT4,ERI2,FIGN,RFX3,SLC25A36,RIC8B,EXD2,ROBO2,PCMTD2,BAALC,GLDN,ADAL,LRRK2,FAM192A,SATB1,SCP2,SEC14L1,CASC3,TRA2B,SGK1,KIF21A,ASAP3,HKDC1,ST6GAL1,ANKRD6,FAM81A,DHX30,PKNOX2,ARHGEF40,ATF7IP,TET1,RCOR3,LIMCH1,SNAP25,SNCA,TRERF1,BDP1,ZC3H13,ZNF302,LARP4,ERBIN,SEPT8,TTBK2,ADHFE1,KLHL7,VPS13A,C12orf76,ANKRD12,TAF9,KLHL4,TCEA1,SATB2,CUX2,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SIK3,HEY1,TLR4,TP53BP2,C9orf85,FAM155A,UBE3A,TOM1L2,TBC1D15,RICTOR,GUSBP1,XPO1,ZIC2,KCNT2,ZBTB38,REEP1,ZNF184,ZSCAN26,SPIRE1,UPF3A,SLC30A4,EMSY,TMEM178A,SEMA3B,SMIM8,JMJD1C" MicroRNA hsa-miR-4330:mirSVR_lowEffct hsa-miR-4330:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-92 7.52E-89 1.65E-91 1.52E-90 272 1763 "ACADM,CLK4,SYS1,FMNL2,KLHL32,ADCY6,RNF157,ADD2,ADORA2A,KIAA1211,ESYT2,BEND6,OSBPL1A,WDR35,OSBPL8,CC2D2A,C1QTNF3,ARHGAP20,FAM135A,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APC,VAT1L,CDK10,ARNTL,NCOA1,ZNF582,RNF182,ADGRB3,SEC11C,ZNF599,KSR1,SYNJ2,ARHGEF7,CASTOR3,MTMR3,GYG2,CALB1,CAMK2B,CH25H,SPAG9,ARHGEF25,CBS,USP6,MTMR7,AP4M1,DCLK1,ARHGAP33,MAGI1,RCBTB2,SRSF11,SOCS6,NDST3,NRXN3,NGEF,FBXO7,ABCG2,CNR1,CNTN1,AKAP7,ARMC8,AKAP6,WHRN,COL4A5,SUMF2,MYRIP,RBM39,CRY2,ANKRD44,LRRC3B,PHACTR3,CST3,PUM1,DCAF4,CYBB,ZFYVE16,EARS2,DGKB,SPOCK2,DBI,AIF1L,GIT2,ARMCX4,GSDME,RHOBTB1,FAM107B,NR1D2,DMTF1,PDCD6IP,FAM78B,MAMLD1,KRBA2,SEMA3D,TMTC1,CELSR3,MBNL2,GOLGA7,EIF5,IRAK4,STARD3NL,EIF1,EPB41,ERBB4,DENND4A,DNAJC27,GMPR2,CLVS1,TMEM132C,FCGRT,SUCO,UBE2E3,PCYOX1,ANKFY1,HVCN1,ZNF605,KHDRBS3,CELF1,MSANTD4,DOT1L,ABLIM2,B4GALNT1,ZNF274,ERAP1,TMEM8B,KIAA1841,GATM,IGSF5,ALDH1L1,MSTN,ARFIP1,ADAM28,DHRS4,HPGDS,ADGRA3,STON1,PCLO,SERP2,FAM19A2,RNF165,RABL2A,SYNPO,AGBL5,LRRC25,NKD1,LRRCC1,IL6ST,JAK2,A1BG-AS1,IPO5,SFXN5,PIK3AP1,MAP4,CHIC1,MEIS1,COL28A1,HS6ST3,LYRM9,MYO7A,NELL2,ALDH1L2,OCRL,CHAMP1,OPA1,ZNF713,PCDH9,PCSK5,ZNF655,CCSER2,PLCL1,SMIM7,ANKRD16,PPM1B,ANKHD1,PTPRN2,PEX2,STRC,TMEM255A,SH3TC2,FAM184A,OXR1,RADX,GTDC1,ZFHX4,CCDC82,SETD5,ALG9,CCDC102B,FBXW7,GLDN,FAM161B,ABCA11P,ST6GALNAC6,SBF1,CSRNP3,FOXRED1,MRAS,SCAF8,FRMPD1,FBXO11,ANKRD6,ABLIM3,PEX26,PPP4R3A,EPN2,KANSL3,KDM4D,ARHGEF40,CCDC88A,SLC12A2,ELMO2,SMARCD3,RCOR3,MBD5,CMTR2,SNRPN,BDP1,FNBP1,ZNF423,TSPYL2,CLASP2,SAMSN1,SS18,NXT2,STAU1,ADHFE1,SUPT5H,SYNE2,PLCB1,SYN2,SYP,SYT1,TAF9,FAM208A,ATMIN,TCF4,DOCK9,PCDHB4,USP32P1,FAM200B,ZNF106,SLC44A1,HEY1,PIK3R5,RGMB,TRIO,TRO,PPIL6,ANKRD20A2,LINC00689,OSBP2,BCL2L13,LAT2,CLDND1,ZNF711,ZNF24,ZNF32,KCNT2,LAMP5,EMSY,RNF103,NAV3,KCNAB1,FAM47E,FZD3,DOCK8,KAT6A,HNRNPA3,FBXO36,CASC15,ST8SIA2,CPNE4,SENP7" MicroRNA hsa-miR-153-3p:TargetScan hsa-miR-153-3p TargetScan 1.51E-92 8.43E-89 1.85E-91 1.70E-90 165 623 "ADD1,HECW2,KCTD16,OSBPL6,DOC2A,APBB2,APC,CASK,ARNTL,CDK13,PCDHGB4,ATP2A2,ATP2B2,ADAM23,LDLRAD4,CACNA1B,CACNB4,CAMK2G,RUNX1T1,CCNT1,DCLK1,MAGI1,DLGAP2,CFL2,CLCN3,CLTC,QKI,CNN3,IQCK,AKAP6,RCHY1,BAG4,C2CD2,CREM,CRMP1,PLXNA4,CCDC144A,ELMSAN1,MFAP3L,KLHL3,DLX1,DMD,CDON,CPEB2,HIPK3,KLHL5,FSD1L,RGS17,GPHN,RASL12,SCML2,CHST15,FOXO3,NBEA,CAMKK2,ATP2C1,DOT1L,FYN,PPARGC1A,KDM2B,FERMT2,GPR37,PCLO,GRIK4,RNF165,MAP4K5,FRMD5,BACH2,MIER3,KCNB1,KCND1,KCNK3,KCNQ3,KPNA5,LIMS1,PAXBP1,MAT2A,MATN2,MEF2C,KCTD6,SCAMP5,MITF,AFF1,MOV10,MYO5A,NCAM2,NEFM,NF1,NFE2L2,NFYA,NOVA1,PCDHGC3,PCDH8,PDE4D,PIK3R1,CCSER2,MTRF1L,LRP12,PPP3CA,KANSL1,PRKAB2,PRKACB,MAPK4,EPDR1,PTCH1,PTPRD,OXR1,RASGRF2,ERI2,FIGN,RIC8B,LGI2,ROBO2,RYR3,SATB1,ATXN7,SCN8A,FAM102A,PKNOX2,ARHGEF40,BTBD7,CPEB4,EPC1,GKAP1,NMNAT2,HECW1,RBM26,NFASC,CLASP2,PLCB1,DMXL2,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,PCDHA7,CRTC1,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CBX5,FAM124A,FLRT2,RICTOR,KCNK12,EML6,DPYSL5,LAMP5,CADM2,NAV3,RGS7BP,FZD3,FXR1,GAN" MicroRNA hsa-miR-378*:mirSVR_lowEffct hsa-miR-378*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-92 8.81E-89 1.93E-91 1.78E-90 284 1916 "EMILIN3,SYS1,ESYT2,AP2A2,MTUS1,HECW2,AK2,C1QTNF1,SMIM17,CEP126,EP400,PI16,MYH7B,PARG,EPB41L5,UPRT,ARHGDIG,MARK4,NCOA1,CCAR2,ATP2B2,SLC2A11,N4BP2L1,DPY19L3,ATP6V0A1,DOCK11,ADAM15,BCHE,CFLAR,BMPR1B,SYNJ1,SCAPER,CAMK2G,SPAG9,METTL6,MTMR7,CBFA2T2,L3MBTL4,TIGD7,NUMBL,CACNA2D2,DIS3L,CNOT8,SULT4A1,IGLON5,WHRN,LETMD1,COL11A2,SLC4A8,CREM,ANKRD44,NCOR1,CLIP3,ABCG1,SNCAIP,CSNK1E,VAC14-AS1,PDE4DIP,APPL1,RIMS2,ZSCAN23,DOCK4,MYADM,RIPOR2,ZFYVE16,LONRF1,DGKG,TMEM170A,AIF1L,HEPH,MYEF2,KIAA0753,LYPD1,ZC3H11A,GUCD1,PARD6A,SPOCK3,TMCC2,FAM107B,DLX1,GRIN3A,DMPK,HS3ST2,RPS6KL1,DOCK2,DPP6,SLC25A18,ACOT8,RCAN1,DTNB,MAMLD1,ABCC5,DNM1L,SNX29,CNNM1,SEMA3D,KLHL5,TENM1,C3orf18,PAN3,COQ7,IGSF6,VPS26C,ADGRV1,PTK2B,FKTN,GTF2IRD2,POLR1B,FGF11,FGFR1,BAIAP2,TMEM164,POLK,SUCO,HPCAL4,FLNC,FLT1,TMEM107,ZNF605,ERGIC3,DOT1L,TVP23A,HRASLS5,GABRA3,FAM120B,ERAP1,TMEM8B,GCNT2,TUBGCP4,SULT1C4,GFRA2,PCDH17,CSDC2,ZNF276,ZNF638,ZNF782,PRUNE2,LPAR4,GRIA2,DIDO1,GRM2,LINC01089,CLASRP,ZBTB49,AP4S1,IRAK3,RASSF8,NCKAP1L,ARHGAP36,HMGCL,HNF4G,ZNF491,FAM95B1,IL6ST,LRRTM1,SLC35G1,GATD1,A1BG-AS1,L1CAM,NCOA7,SMAD9,MATN2,MBP,ADAM11,MEIS1,MIA2,KITLG,MITF,XRRA1,MYO9A,ZNF862,NEK1,NELL2,NF1,ALDH1L2,NFYA,NNAT,NOVA1,PCBP3,OXTR,P2RX7,PDE4A,PFKFB2,NALCN,XRN1,GPSM2,ZNF426,MTRF1L,PURG,DRAM2,MINDY2,CEP41,EPDR1,MAPK10,GDPD1,RELN,CNNM2,SAMD9,BCAS3,SPDL1,ZSCAN2,CEP97,SLC25A48,ACSS3,RASGRF1,RASGRF2,DPF2,FIGN,PBRM1,RNASEL,CCDC82,GSTCD,CYB561D1,ELP2,MRAP2,SNX22,NEK11,FAM161B,HSD11B1L,HSPA4L,KIF21A,PPM1E,KIF16B,HKDC1,CHD9,PEX26,EPN2,DHX30,SLC12A2,ELMO2,ATF7IP,ZNF667,SMARCA4,ANKRD36,LIMCH1,MBD5,FNBP1,NMNAT2,SPP1,KDM4C,DIP2A,STXBP1,SUPT5H,SYNE2,EXOC7,FAM208A,TCF4,ZFP90,ZEB1,TPCN2,SYNE1,PCDHB15,PCDHB7,GPRIN3,RNF216P1,AP4E1,TMEM9,BHLHB9,LRRC8A,CSMD1,RGMB,SYNPO2,ELP5,STXBP4,RUSC1,HIRA,UBE3A,PLEKHH2,ZNF23,KCNT2,LYPD6,SMARCAD1,TMEM178A,HPS4,MPPE1,FAM13C,DOCK8,KAT6A,FBXO36,ADAMTSL3,NLRP3,IFT88,SOCS4,SPATA13" MicroRNA hsa-miR-651:mirSVR_lowEffct hsa-miR-651:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.93E-92 1.08E-88 2.35E-91 2.17E-90 251 1510 "C3orf14,NCKAP5,ADCY8,KIAA1211,SLC24A4,KCTD16,NME5,WDR35,TAOK1,SEMA6A,ALCAM,OGT,APBB2,UPRT,VAT1L,BCAS1,USP37,TMEFF1,CADPS,ATP2A2,N4BP2L1,SEC11C,BCHE,BMP7,GYG2,CA8,CAMK2B,ISPD,LRBA,DCLK1,ZMYM4,QKI,HECTD1,CNN3,AKAP7,AKAP6,COL4A5,AKAP5,RTTN,MYRIP,CNRIP1,CREM,HAPLN1,TRIM69,SNCAIP,CSF1R,SEC24C,CSNK1E,OSBPL3,SUSD5,PHACTR3,DZIP3,PLCXD3,DOCK4,RIPOR2,ZFYVE16,RASSF2,KCTD8,DAPK1,PLPPR4,MTX3,WDR20,DYNC1I1,DPYSL2,DRP2,PDCD6IP,ECM2,MAMLD1,E2F5,KLHL5,FRY,EIF5,PAN3,USPL1,TUBD1,GPHN,ETV1,RRAGB,KATNAL1,HSPA12B,F8,TMEM132C,FCGR3A,GTF2IRD2,FGF12,BAIAP2,AMOTL2,PRKAG2,UBE2E3,ANKFY1,C2orf88,TPK1,ZNF605,ST6GALNAC3,DLL3,MPP6,FYN,GABRB3,GABRG1,DISC1,ALDH1L1,MSTN,AHDC1,USP19,GGT5,BRD8,TCERG1,SPIN1,TOX3,LUZP2,WDFY3-AS2,GPD2,PRUNE2,STMN2,GRIA2,CIT,AP4S1,FAM222A,BACH2,MIER3,HLF,ELOVL5,SHISA6,MSL1,SHISAL1,MYLK2,IGF1,ZIC5,IL6ST,ITGA7,SYTL4,MARK1,MBNL1,CHST6,CHIC1,MEF2C,MEST,MIA2,ZNF680,COL28A1,MSI1,BLOC1S2,HS6ST3,MYO6,NF1,NUCB2,CHAMP1,OXTR,CNTN3,PDE4D,ENPP2,PFKFB3,SERPINI1,NALCN,PIK3R1,RETREG1,PURG,LRP12,ING3,PPARA,TATDN3,RANBP3L,SAMD9,WBP1L,APTX,MTMR10,PTN,PEX2,TMEM255A,RASGRF1,RADX,ZMAT4,GTDC1,ZFHX4,SETD5,EXD2,C12orf49,CCDC102B,MCMBP,RPS6KA2,CSRNP3,ATXN2,SCP2,SEC14L1,CASC3,TRA2B,KIF21A,SH3GL3,FERMT1,CHD9,FBXO11,DZIP1,PKNOX2,SIRT2,SLC14A1,BTBD7,MBD5,CABCOCO1,USP33,UHRF1BP1L,CDK19,CLSTN2,NKAIN2,NXT2,DIP2A,NSFL1C,KLHL7,NECAB1,ARHGEF9,SYN2,ANKRD28,ADGRL3,ZFP90,TCF12,DOCK9,OBSL1,FRYL,SIRT1,ZFPM2,ARL10,ACTR6,TLR4,ERCC6L2,R3HDM1,CSMD1,TPM1,NPL,DOK6,SMUG1,TSC1,UBE3A,LINC00689,UGT8,ZBTB14,ZNF711,ZNF24,ZNF74,LYPD6,ZBTB38,TMEM237,SMARCAD1,EMSY,CADM2,PDSS2,EPM2A,JMJD1C,KLHDC1,NETO1,GAN,LAS1L,SENP7" MicroRNA hsa-miR-758:mirSVR_lowEffct hsa-miR-758:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.30E-92 1.28E-88 2.80E-91 2.58E-90 247 1464 "KCNH8,ABHD6,XKR4,KIAA1211,OLMALINC,MTA3,OSBPL1A,TXNDC16,ZNF578,HFM1,ALCAM,OGT,DPP10,LRCH2,ANK2,APAF1,UPRT,PPP4R4,TMEFF1,CDK13,TMEM108,EIF4G3,BCHE,MIR9-3HG,KSR1,BMPR1B,SGCE,CACNA1G,IL33,CALB1,PRC1,LRRFIP1,DLGAP1,RCBTB2,SOCS6,RAB28,ABCG2,QKI,CNTN1,AKAP7,FAM149A,AHCTF1,BAG4,MYRIP,ANKRD44,SEC24C,ARHGEF10,IPCEF1,FAM131B,KIAA0408,HDAC9,MYADM,ARHGAP24,ZFYVE16,KIAA0586,KCTD8,DGKG,IP6K1,PABPC5,HEPH,DDX46,RHOBTB1,SGSM2,CHRDL1,GRIN3A,DMD,CDON,DMTF1,SLC12A6,ECM2,EBF1,EDN1,KMT5B,EIF4G2,EIF1,TUBD1,SPEG,KATNAL1,FECH,SLC9B2,MED12L,FGF12,FHL1,SUCO,MEX3B,NOP56,PDLIM5,RASL10A,ERGIC3,SARAF,CHL1,IP6K3,SYT17,SRRM4,BRD8,FERMT2,LNX1,ADGRA3,GPD2,FUT10,GPR37,GRB10,GRIA2,C1QL4,GRM8,RNF165,BACH2,ELOVL5,AGBL5,USP51,AGFG1,MSL1,IDH3A,FAM95B1,IGF1,RBPJ,IL6ST,GPR62,CREG2,KPNA5,IPO5,LIG4,MAN2A2,ZFYVE27,MARK3,MBNL1,CHST6,CHIC1,LRP1B,PPM1L,MITF,MMP16,MSR1,MYO7A,ZC3H12B,NDP,NELL2,GPR137C,PCDH9,PCSK5,PDCD2,PDE4B,GPR85,PFKFB4,PURG,ANKRD16,SCHIP1,SDK2,PPM1B,PPP2R5E,RASGEF1B,PRKACB,EPDR1,MAPK9,APTX,CNTLN,TMEM260,PTPRB,TMEM231,NWD1,ZNF493,RASGRF1,MSANTD2,FIGN,RGS12,RIC8B,PBRM1,ZFHX4,SETD5,PCMTD2,CCDC102B,RPL15,ATP8B4,GLDN,CLIP1,SATB1,LRFN5,TNFRSF19,GALNT10,SUPT20H,FHOD3,ANKRD6,KDM4D,SEPHS1,ARHGEF40,SLC12A2,ELMO2,ANKFN1,FAIM2,SNRPN,TMCC1,FAM126B,PDZRN3,BDP1,KDM4C,TEX2,PEG10,SPTAN1,RBM26,DDN,SPART,SEPT8,KANK1,SEPT3,SYNE2,SYPL1,COBL,TACC1,CAMTA1,DMXL2,CUX2,ZEB1,TPCN2,PCDHGA11,SYNE1,PCDHB4,DICER1,ITGB3BP,AP4E1,SLC44A1,MTMR14,HEY1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,TTTY15,LINC00689,UGT8,FLRT2,PLEKHH2,RBFOX3,P2RY12,GUSBP1,SLC47A2,MKRN3,ZFAND5,EMSY,CADM2,SLC38A1,FAM13C,AMN1,FZD3,RTN4,RNF170,NETO1" MicroRNA hsa-miR-155*:mirSVR_highEffct hsa-miR-155*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-92 1.52E-88 3.30E-91 3.04E-90 228 1248 "SYN3,NCKAP5,BRAP,ADORA2A,KIAA1211,RNF150,KLHL13,CC2D2A,HFM1,C1QTNF3,LRCH2,ANK2,EP400,LCORL,PPFIA4,CASK,RGS20,MARCH3,ATP1B3,N4BP2L1,ZNF599,BMPR1B,DST,NAE1,SCAPER,CA8,CACNB4,LURAP1,PTBP2,PRC1,CLDN10,KRIT1,USP6,CBFA2T2,SCARB1,SEPT7,LRRFIP1,NOG,CFL2,SRSF11,CHN2,NDST3,SULT4A1,AKAP6,COL4A5,SLC4A8,ABI3BP,PREPL,ANKRD44,GDA,ARHGEF10,SIPA1L1,PHF14,CTH,GREB1,HDAC9,KIAA0586,DAPK1,PABPC5,ZC3H11A,ALKBH8,SGSM2,CHRDL1,USP3,DPYSL2,PDCD6IP,RCAN1,DNAJB6,ABCC5,EDIL3,WDPCP,EDNRA,ANKRD46,KLHL5,GOLGA7,DCTN4,LRRC17,MTSS1L,IGSF6,CEP85L,ABCA8,DLC1,FCGR1A,MED12L,TMEM164,FHL1,JKAMP,NBEA,SARAF,MPP6,ABLIM2,MEGF10,B4GALNT1,ZNF559,DISC1,LRRC37A6P,MALT1,TCERG1,DBF4,RAB30,ZNF638,LNX1,LILRA2,GRIA2,ATE1,RNFT2,BACH2,ELOVL5,SMAP1,MSL1,ZNF181,LRRCC1,ITGAM,KCND2,CREG2,STXBP5,STMN1,LIG4,MBD1,MBNL1,MEF2C,MGAT3,AFDN,BLOC1S2,ZNF92,NF1,NME4,NPTX2,ZNF713,GLIPR1L2,ETFRF1,ENPP2,PIK3R1,FAM218A,PLCL1,PDZRN4,LRP12,EPB41L4B,TATDN3,MAPK9,HYDIN,DCHS2,SNRK,CNTLN,TMEM260,USP47,OXR1,RDX,TRIM68,REV3L,ERI2,GTDC1,UBR7,RGS12,SLC25A36,TMLHE,C12orf49,CARF,RORB,ARMH4,SPIN3,TNFRSF19,ZFP2,SUPT20H,FHOD3,SEC31A,CCDC88A,SLC11A1,ZNF334,SLC22A4,USP33,PEG10,LMO3,ZNF302,ZSCAN29,NEK4,ADHFE1,SEPT3,SYNE2,PLCB1,SYPL1,C12orf76,DNMBP,TAL1,ADGRL3,AGTPBP1,TPCN2,TRIM2,CLASP1,SYNE1,PCDHB6,FRYL,SIK3,RNF216P1,DNAH7,AKTIP,ASXL3,BHLHB9,ERCC6L2,TPM1,SYNPO2,METTL3,STXBP4,ANKRD20A2,HIRA,TUBB1,UBTF,UGT8,ZNF781,XRCC4,ZBTB14,ZNF28,CELF4,ZNF154,ZSCAN26,FTSJ1,SMARCAD1,EMSY,PLSCR4,FAM13C,AMN1,FZD3,DOCK8,RTN4,UBE3B,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-302a*:mirSVR_highEffct hsa-miR-302a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.22E-92 1.80E-88 3.90E-91 3.59E-90 248 1478 "CLK4,FMNL2,GALNT16,CCDC85A,ADCY8,TMCC3,BRAP,PWWP2A,DPY19L2P4,MTUS1,PCDH19,HACE1,NME5,SEMA6A,PCDH10,UNC79,AMPD2,LRCH2,MAP4K3,PARG,FAM131A,CDK13,STK33,STX16,ADGRB3,BBS2,MPDZ,SYNJ2,WASF1,IL33,CACNB4,CABP7,PTBP2,KYAT1,CDH2,L3MBTL4,LOC730101,DLGAP2,TIGD7,CCPG1,NDST3,QKI,HECTD1,MAP4K4,IQCK,ARMC8,AKAP6,COL4A5,MYRIP,AKAP12,CS,KATNAL2,GAPVD1,TCAF1,MATR3,DGKB,TMEM170A,YTHDC1,MYEF2,GSDME,SACS,WDR20,DMD,DMTF1,EBF1,WDPCP,EDNRB,FSD1L,OPTN,FAM13A,COPS4,PAN3,DCTN4,EXTL2,EYA1,ARMCX1,TMEM132C,DLC1,ST3GAL6,GORAB,SLC9B2,FGF13,FGF14,AMOTL2,SUCO,MEX3B,HPCAL4,FOXF2,FLT1,EFCAB2,JKAMP,NBEA,STAU2,OGA,MEGF10,DISC1,ARFIP1,GHR,PPARGC1A,TXNL4A,GLYR1,TNRC6A,PRUNE2,GPR12,GRIA2,UBE2QL1,ELOVL5,SHISA6,MSL1,IDH3A,C2orf72,ZIC5,RBPJ,LRRCC1,ZNF678,LRRTM1,CREG2,LAMP2,LIMS1,SMAD1,SMAD9,MAP2,MARK1,LYPLAL1,MARK3,MBNL1,LRP1B,SHC3,MEIS1,SRSF12,MIA2,NELL2,NF1,NNAT,NME4,NOVA1,SLC11A2,CHAMP1,OXTR,GPR137C,GLIPR1L2,MTRF1L,MAPKAP1,LRP12,SCHIP1,ING3,RETREG2,SEPT4,PPM1B,LRRN3,PPP2R5E,RANBP3L,PRKCB,VPS13C,WBP1L,SNRK,CNTLN,ANKHD1,PTPRE,ZNF615,MARCH1,USP47,CCDC40,FAM66C,RET,ZFHX4,SETD5,TMLHE,GSTCD,ROBO1,ROBO2,RORB,PCMTD2,ARMH4,SPIN3,ADAL,ABCA11P,FAM192A,AP1AR,SCP2,ARX,AMBRA1,FBXO11,FNDC3A,CNKSR2,CCDC92,PPP4R3A,TET1,SMARCC2,RCOR3,LIMCH1,SNAP25,SNCA,SNRPN,PDZRN3,PDZD2,KDM3A,PEG10,RBM26,SPART,NFASC,PBLD,SSTR2,NKAIN2,NXT2,SULF2,SYNE2,SYT1,ZEB1,SLC19A3,PUM2,CCDC173,PMS2CL,DICER1,ITGB3BP,ZMAT3,TLR4,KAT6B,TRO,SGK3,ZNF610,OSBP2,CCDC14,TBC1D15,WIPF1,ZNF781,XPO1,ZNF711,ZNF24,MKRN3,ZBTB38,ZNF189,UPF3A,EMSY,CADM2,STOX2,ADAMTS9,FIP1L1,PLSCR4,FAM13C,AMN1,RTN4,UBE3B,PHTF2,ACTR3B,ADAMTSL3,RNF170,FXR1" MicroRNA hsa-miR-548b-5p:PITA hsa-miR-548b-5p:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548c-5p:PITA hsa-miR-548c-5p:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548d-5p:PITA hsa-miR-548d-5p:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548j:PITA hsa-miR-548j:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548a-5p:PITA hsa-miR-548a-5p:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548i:PITA hsa-miR-548i:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548h:PITA hsa-miR-548h:PITA_TOP PITA 3.30E-92 1.84E-88 3.94E-91 3.63E-90 189 844 "FMNL2,ZNF608,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ZBTB10,NCOA1,NUMB,SLC4A4,ADGRB3,JAZF1,SPAG9,KRIT1,DLGAP2,CFL2,FOXN3,CHN1,LHX2,CLCN3,HECTD1,MAP4K4,CNR1,AHCTF1,CLOCK,CDC42BPB,C2CD2,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,ZFYVE16,MATR3,MAML1,ELMSAN1,RHOBTB1,SNAP91,SACS,SPOCK3,RAB39B,DMTF1,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,TAOK3,SEC24B,FGF12,PRKAG2,AFF2,NBEA,PDLIM5,STAU2,MEGF11,GABRB3,MTHFD2,C15orf41,GATM,MSTN,GNAO1,PRRC2B,GPD2,GRB10,CIT,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,INSM1,KIF2A,IPO5,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,MYCN,HNRNPM,NEFM,NOVA1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,NALCN,ZNF655,RETREG1,MINDY2,PPP2R5E,PPP5C,PRKACB,CEP41,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,TRA2B,CHD9,WDR37,ABLIM3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,CABCOCO1,TMCC1,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,CLASP2,ITPRID2,LARP4,SS18,RGL1,NUDT10,ADAMTS17,PLCB1,SYT1,CAMTA1,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,HEY1,KAT6B,TPM1,TRPS1,UBE3A,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-4318:mirSVR_lowEffct hsa-miR-4318:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.61E-92 2.02E-88 4.30E-91 3.96E-90 263 1659 "VWA5B2,GALNT16,ADCY6,ADD1,ADD2,BRAP,MTA3,ZNF608,KCTD16,NME5,TXNDC16,ALCAM,CARNS1,GPRASP2,ZNF687,AMPD2,C6orf89,MYH7B,PKP4,DDO,TMEFF1,TMEM108,ATP1B3,ALDH7A1,BARD1,NRP2,CFLAR,BMPR1B,SYNJ2,KALRN,HAP1,PTBP2,SPAG9,CBS,CCNH,USP2,CD86,ZMYM4,EVI5L,CCPG1,CLGN,COPB2,QKI,MAP4K4,SLC4A8,SMARCAL1,ZFP28,RBM39,AKAP12,CSNK1E,OSBPL3,VCAN,CST3,RASGEF1C,KIAA0040,PLCXD3,KIAA0408,BOC,LONRF1,KIAA0586,SPOCK2,AIF1L,LYPD1,SV2B,WDR20,GRIN3A,DMD,USP3,DYNC1I1,DOCK2,DPH1,DRP2,ARRDC4,ABCC5,DNM1L,SEZ6L2,FCF1,SEMA3D,EBI3,GOLGA7,ASB3,DCTN4,ENO2,EPB41L2,COQ7,RABEPK,CEP85L,MRPL10,RASL12,SIRPB1,FAM198B,TAOK3,CORO2B,DLC1,BAIAP2,POLK,PCYOX1,SYNCRIP,SLC37A3,NOP56,MEGF10,HRASLS5,RAPGEF6,NEU3,MSTN,AHDC1,ADAM28,PCDH17,MALT1,SPIN1,RAB30,POLL,LUZP2,LOXL3,PRRC2B,GPD2,TDRKH,GRB10,PLCD4,PSIP1,ADAMTS6,MAP4K5,IRAK3,MAN1B1,IGF1,IL6ST,LMO2,SYTL4,GPR155,MARK1,MATN2,CHIC1,POC1B,MKLN1,LYRM9,NEXMIF,ZC3H12B,NF1,NOVA1,NPTX1,NUCB2,OCRL,CHAMP1,OGG1,PCSK5,CDK18,PDE4B,NLGN3,ZFYVE21,PLIN1,LRP12,PSAT1,EXOSC10,ING3,MINDY2,KANSL1,SLC26A11,GRAMD1C,SPDL1,PTPRG,C1orf109,PEX2,PID1,USP47,SUSD4,MSANTD2,RDX,ZDHHC4,PRIMA1,SLC25A36,SETD5,PCMTD2,NEK11,FBXW7,ZC3H14,ZNF331,CSRNP3,SUPT20H,TRA2B,FERMT1,FNDC3A,FHOD3,R3HDM2,SYBU,NLGN1,PPP4R3A,KDM4D,ARHGEF40,CCDC88A,TRIM67,ANKRD36,SNRPN,NMNAT2,HECW1,MYCBP2,RBM26,SS18,CEP68,KANK1,TACC1,TACR1,TAF9,DNMBP,TAL1,KLHL4,ATMIN,DMXL2,TCF12,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,SIRT1,ZFPM2,ITGB3BP,ZMAT3,TMEM9,TLR4,TMPO,RIMBP2,RGMB,ZNF346,SYNPO2,METTL3,SMUG1,TRIO,RUNDC3B,RUSC1,TTC3,TUBB1,FAM155A,UBE2H,SLC35A4,OSBP2,PLEKHH2,BCL2L13,RICTOR,GUSBP1,XPO1,XRCC4,ZNF24,TRIM9,LYPD6,SPHK2,CELF4,AMZ1,DPYSL5,DHX33,EMSY,SLC38A1,NAV3,FIP1L1,PLSCR4,RGS7BP,RTN4,KAT6A,HNRNPA3" MicroRNA hsa-miR-146a*:mirSVR_highEffct hsa-miR-146a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.20E-92 2.91E-88 6.19E-91 5.70E-90 260 1625 "KCNH8,NCKAP5,NDRG3,SLC24A4,HECW2,PCDH19,TAOK1,C1QTNF3,ALCAM,FAM135A,CDC42BPA,FGD2,PARG,APAF1,UPRT,APOC1,SFMBT2,TMEFF1,MARCH3,ZBTB10,SYNJ1,NAE1,GYG2,THSD7A,KALRN,VXN,CBR1,KRIT1,MAGI1,TIGD7,CLGN,CFL2,SRSF11,CHN1,B4GALT6,TAOK2,RAB28,PLAA,QKI,LY86,IGLON5,CNN3,ARMC8,RCHY1,FAM171B,SEC31B,ANKRD44,GDA,TRIM69,LRIG1,ARHGEF10,OSBPL3,PDE4DIP,SLITRK5,DZIP3,UBXN2A,GREB1,PUM1,RIMS2,DCAF4,RUBCN,HDAC9,GPRASP1,RIPOR2,ZNF337,DGKB,DGKG,FBXL5,DDX46,GUCD1,RHOBTB1,SNAP91,DMD,RCAN1,DTNA,MAMLD1,DNM1L,EDN3,EDNRB,FRY,FSD1L,YAF2,KMT5B,PLEKHA1,PAN3,EIF1,COQ7,SRRM1,MRPL37,CDKL3,NRN1,FCGR3A,STRADA,FDFT1,POLK,SUCO,ATP13A4,FLT1,SLC37A3,ATP6V1H,ATP2C1,CELF1,OGA,FYB1,GAD1,ZNF559,CPLX2,KIAA1841,ALDH1L1,SULT1C4,MSTN,WASHC2A,NFU1,ADAM28,PCDH17,SPIN1,GPR12,SERP2,ATE1,GRM8,GSN,RASSF8,HLF,HSF2,SHISA6,SMAP1,IRF8,FAM95B1,TJAP1,IL6ST,ZNF678,ITGAM,CREG2,KTN1,STMN1,PAXBP1,SYTL4,HECTD2,MAP6,MAT2A,MATN2,MBNL1,MEIS2,XRRA1,MSR1,PTOV1,MYO9A,P2RY13,NFYA,NOVA1,NRCAM,NUCB2,PCSK5,OLA1,ABCB1,FAM218A,RETREG1,JAKMIP1,SCHIP1,MINDY2,PPM1B,LRRN3,PPP2R5E,KANSL1,RANBP3L,PRKAB2,MAPK4,PTCH1,TMEM260,PTPRD,PTPRG,ACSM5,RIPOR1,TMEM255A,ACSS3,SH3TC2,FAT4,RBBP6,MORC4,SLC25A36,LGI2,YY1AP1,PCMTD2,CCDC102B,NEK11,TCP11L1,ABCA11P,CCDC112,ATXN2,ATXN7,CHD9,KBTBD4,BTBD7,CPEB4,ZFP1,OGDHL,IFT122,ANKRD36,SNRPN,USP33,SOX3,BDP1,KDM4C,ZNF423,ZC3H13,TROVE2,CLSTN2,ITPRID2,SSTR2,LARP4,STAU1,ZC3H4,NUDT10,ADAMTS17,SYPL1,C12orf76,DNMBP,CUX2,TCF12,SYNE1,TNS2,FRYL,SLC44A1,ERCC6L2,TMPO,BEX4,RIMBP2,SMUG1,TRIO,RUNDC3B,AMACR,PPIL6,RPL7L1,UBE2H,UBE3A,ZNF709,VLDLR,LAT2,GUSBP1,PCDH20,ZNF711,MICU3,LYPD6,AMZ1,ZSCAN26,ZNF189,STOX2,ADAMTS9,CIAPIN1,VPS35L,MPPE1,WNK3,EPM2A,FAM13C,RTN4,ADAMTSL3,RNF170,SNX14,IFT88,PRRT4" MicroRNA hsa-miR-19b-1*:mirSVR_highEffct hsa-miR-19b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.45E-92 3.61E-88 7.66E-91 7.05E-90 232 1298 "FMNL2,KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,VAT1L,PPP4R4,SPTBN4,NUMB,EIF4G3,BACH1,BCL7A,MTMR2,SGCE,IL33,CACNA1B,CACNA2D1,CALM1,KALRN,PTBP2,CAMK2G,CAST,LRRFIP1,NOG,CFL2,CBARP,SOCS6,NRXN3,PPT2,FBXO7,FAM189A2,C4orf33,CNN3,ARMC8,SUMF2,RCHY1,MYRIP,IGDCC3,SLC35F1,FAM171B,CLOCK,CSNK1G3,SUSD5,PLXNA4,PHF14,CTH,USP6NL,ARHGAP32,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,RHOBTB1,FAM107B,NR1D2,CPEB2,DTNA,EDN1,EDN3,EDNRB,RASGRP1,PHF20L1,EGFR,EIF4G2,EMX2,LRRC17,STX2,CEP85L,CDKL3,TLR7,TMEM132C,TAOK3,DLC1,FDFT1,SUCO,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,ATP2C1,CELF1,MEGF10,CHL1,GATM,NEU3,WASHC2A,AHDC1,ADAM28,TXNL4A,GLI2,ZNF638,GNAO1,FERMT2,GRB10,SOX21,HAS2,FRMD3,ARHGAP36,HNF4G,NEGR1,SHISA6,SMAP1,ZNF678,KCND2,KCNN3,STXBP5,TTYH2,LAMA2,PAXBP1,ASPRV1,PIK3AP1,MARK1,MATN2,EFHB,KCTD6,MIA2,PPM1L,MITF,MYO9A,SFR1,NF1,NFE2L2,SMIM11A,OGG1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,PDE4D,OLA1,NLGN3,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,CCDC144B,MAPK10,HYDIN,ELOVL2,PTK2,PTN,STK32A,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,SPIN3,MCMBP,ABCA11P,HSD11B1L,RTN1,SATB1,ATXN7,SCN7A,FNIP1,KIF21A,CPEB3,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,MYO16,KDM3A,SP4,ZC3H13,ZC4H2,NXT2,RGL1,VPS13A,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,PCDHB9,OBSL1,PUM2,NR2E1,TMPO,C9orf85,SYNPO2,TRO,ANKRD20A2,TUBB1,RPL7L1,FAM155A,UGT8,P2RY12,GUSBP1,XPO1,XRCC4,CFAP298,ZNF28,KCNT2,ZNF540,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,SPIRE1,STOX2,TMEM178A,NAV3,PDSS2,FZD3,KLHDC1" MicroRNA hsa-miR-617:mirSVR_lowEffct hsa-miR-617:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.56E-92 5.35E-88 1.13E-90 1.04E-89 245 1450 "ADCY6,SORCS2,SRPX,PCDH10,FAM135A,PHF12,KCNAB2,TNRC6C,IGDCC4,PLA2G4C,SYNJ1,MYRF,CACNA1B,KALRN,PTBP2,VXN,RUNX1T1,P2RX6,LRBA,LRRFIP1,L3MBTL4,LARGE1,SOCS6,CHN2,CLCN3,C4orf33,SRP14-AS1,ARHGEF6,CNR1,COL4A5,AKAP5,ABI3BP,TBPL1,C2CD2,CRMP1,NCOR1,ARHGEF10,CSNK1G3,SUSD5,USP6NL,FAM131B,CYBB,HDAC9,TCAF1,DCAF8,TBC1D5,PITPNC1,TIAM2,GSDME,DDX46,MTX3,KIF19,DOCK2,DMTF1,DPP6,PDCD6IP,ARRDC4,EDIL3,EDNRB,ANKRD46,HIPK3,CNNM1,KLHL5,SUGP2,COPS4,EPHB1,RASL12,TUBB3,POLK,UBE2E3,EVL,FLT1,UFM1,RASL10A,KHDRBS3,DOT1L,ZNF234,ERAP1,DISC1,NEU3,USP19,GGT7,PPARGC1A,CRCP,MSL3,ZNF638,KDM2B,ADGRA3,LILRB4,PRUNE2,STMN2,GRB10,GRIA2,FAM107A,SLC2A6,FAM222A,HAS2,PADI2,HLF,GABARAPL2,SYNPO,HMGCR,HNF4G,C9orf129,IRF8,IDH3B,C2orf72,IGF1,KNDC1,TJAP1,DISP2,SCIN,KCNB1,GPR62,KIF5A,STXBP5,KTN1,STMN1,LIMS1,HECTD2,SMAD1,LRP1B,MEIS1,KCTD6,MID1,MITF,XRRA1,COL28A1,NRBP2,LYRM9,MYO5A,HNRNPM,NBL1,CNOT4,SMIM11A,OCRL,PCDH8,PCSK5,PDE4A,PDE4B,GNG2,SEMA5B,PIK3R1,KCTD15,PLCB2,ANKRD16,LRP12,EPB41L4B,POU6F1,PPM1B,CCDC144B,NKAIN4,PRKCB,MAPK4,EPDR1,NDUFS7,WBP1L,CNTLN,ANKHD1,PTN,TMEM260,PTPRB,ZNF493,RET,UBR7,EXD2,KLHDC8A,ALG9,GSTCD,CYB561D1,STK32B,ABCA11P,NCBP3,SATB1,SBF1,ATXN2,HES6,ZNF821,SUPT20H,CHD9,ABLIM3,SLA,PPP4R3A,EPN2,CPEB4,GKAP1,SNCA,MBD5,TMCC1,PDZRN3,DOP1A,SOX11,DOK5,SP4,NMNAT2,GLT8D1,KDM4C,CDK19,TSPYL2,ITPRID2,ZNF302,NKAIN2,RGL1,DIP2A,STX1A,NSFL1C,RHBDL3,PLCB1,SYN1,COBL,ADGRL3,ZFP90,TPCN2,NAT16,TNS2,RNF216P1,DICER1,KHDC1,CHST8,TIAM1,TK2,RIMBP2,SYNPO2,TRO,TTTY15,LINC00689,USP1,VSNL1,RICTOR,AGMO,CRB2,FSTL5,INTS3,DNALI1,SLC38A1,HPS4,URM1,FAM13C,DOCK8,FBXO36,CASC15,TIGD6,RNF170,NHSL1,GAN" MicroRNA hsa-miR-1825:mirSVR_lowEffct hsa-miR-1825:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-91 5.76E-88 1.22E-90 1.12E-89 247 1474 "RALGAPA1,ASPHD1,KLHL32,CCDC85A,PLEKHH1,ADORA1,HECW2,PCDH19,ARHGAP20,DOC2A,AMPD2,ZFAT,EP400,MAP4K3,KCNAB2,CDK10,SPTBN4,CDK13,NCOA1,NUMB,TMEM108,STX16,ATP2A2,ADGRB3,MPDZ,BCL7A,BMPR1B,SYNJ2,FUBP1,CACNA1I,CACNA1B,DDR1,HAP1,CAMK2A,CAPN3,CH25H,SPAG9,CERS5,USP2,CBFA2T2,CD38,SEPT7,DLGAP1,CCPG1,CLGN,NOG,UBE2L6,B4GALT6,RAB33A,SULT4A1,SRP14-AS1,HECTD1,CNR1,AKAP7,IQCK,FAM149A,AKAP6,LETMD1,CS,PDE4DIP,PHF14,RUBCN,CCDC144A,CYBB,KATNAL2,DGKB,SPOCK2,AIF1L,B3GAT3,RUSC2,POM121,PLPPR4,SNAP91,SACS,TMCC2,WDR20,RAB39B,MED12,SLC29A4,SLC12A6,DUSP9,ABCC5,FRY,YAF2,SUGP2,EGFR,PAN3,ERBB2,REEP2,FCGR1A,MED12L,TMEM164,AKAP3,NBEA,TMEM107,APOPT1,ATP2C1,ZNF605,NSG1,GHDC,SIGLEC8,DISC1,TUBA8,SRCAP,ARFIP1,AHDC1,ADAM28,PPARGC1A,TTBK1,TCERG1,TOX3,GLUL,AIFM3,STARD3,MAP7D2,RAB40B,GRB10,ADAMTS13,GRM2,FAM19A2,RNF165,NCKAP1L,HLF,CPT1C,DHX35,SHISA6,KIAA1755,KCNJ16,KCNK3,SFXN5,PAXBP1,HECTD2,ZFYVE27,MBNL1,CHIC1,MEIS1,MKLN1,NEFM,NFYA,CNOT4,NOVA1,DNHD1,SLC11A2,LOC100128398,CDK18,SNX10,PKM,GPSM2,NLE1,FAM216A,PURG,PRIMPOL,PMP22,RETREG2,SH3KBP1,PPARA,PPP2R5E,PKIA,PRKCB,MAPK4,EPDR1,GRAMD1C,PIGG,PTK2,TMEM260,RIPOR1,TUG1,RIC8B,PBRM1,RNASEL,ARMC5,ROBO1,ELP2,EPHA10,BAALC,ZC3H14,SGSM1,CLIP1,RXRA,SATB1,CSRNP3,SCN8A,SCP2,FOXRED1,SUPT20H,AMBRA1,FBXO11,R3HDM2,NUBPL,BTBD3,WDR47,FAM214B,KANSL3,ZNF430,SLC9A5,CPEB4,SMARCC2,RCOR3,SNCA,SNRPN,TMCC1,USP33,TEX2,ZBTB43,DDN,PRRC2C,PLCB1,ANKRD12,MTCL1,EXOC7,TCF4,ZFP90,ZEB1,TRIM2,DOCK9,FRYL,DNAH7,DICER1,SIRT1,ZFPM2,AP4E1,MTMR14,TMEM9,RELL2,TMPO,TPM2,TRO,DCBLD1,TST,TTC3,CLHC1,UBTF,OSBP2,TRIM9,EML6,SPIRE1,SMARCAD1,UPF3A,CADM2,DNALI1,STOX2,FAM47E,FAM13C,FZD3,CASC15,FXR1,NETO2" MicroRNA hsa-miR-1260b:mirSVR_lowEffct hsa-miR-1260b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-91 5.86E-88 1.24E-90 1.14E-89 273 1791 "ASPHD1,ABHD6,TMEM132B,GALNT16,GALNT13,AXIN2,LRFN2,CC2D2A,TAOK1,UNC79,FAM135A,SYT13,PDZD4,OGT,SEMA7A,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,PHYHD1,VAT1L,TNRC6C,AQP6,SEMA4G,SPTBN4,ARRB2,DNAH17,MARK4,TMEM108,ATP2B2,ZNF583,BBS2,BTK,CACNA1I,CACNA1G,CA4,CACNB4,KALRN,ARHGEF25,CBLN1,KRIT1,P2RX6,CDC25B,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,TAOK2,ARHGAP22,LHX2,ARHGEF6,COL4A5,SUMF2,ZNF385A,ANKRD44,NCOR2,ABCG1,RGS6,LRIG1,ARHGEF10,OSBPL3,VAC14-AS1,CST3,PLXNA4,SLITRK5,GREB1,RIMS2,RUBCN,CYBB,RIPOR2,ARHGAP24,DCAF8,RASSF2,LIN54,SPOCK2,AIF1L,GIT2,ARMCX4,ELMO1,C2CD2L,GUCD1,TMCC2,ZNF582-AS1,USP3,NR1D2,CDON,DTNA,DTNB,TOM1,EDNRA,YAF2,CELSR3,KMT5B,COQ7,LRRC17,RASGRP2,MTSS1L,EPHB1,SPEG,ETV1,SIRPB1,EZH1,NRN1,CORO2B,FCGR1A,PPP1R1B,SLC9B2,POLR1B,FGF14,FHL1,FLT1,CAMKK2,ATP2C1,ERGIC3,SARAF,ABLIM2,TVP23A,MEGF11,GABBR1,GABRA3,GAD1,RAPGEF6,SIGLEC8,ALDH1L1,USP19,GGT7,NTNG2,GLUL,DCLK2,LILRB4,TMEM121B,GRIA2,PLPP7,ADAMTS13,RNF165,BVES,PSIP1,PADI2,NCKAP1L,ARHGAP36,VSIG4,ELOVL5,AGBL5,HNF4G,USP51,HSF2,CELF5,SMAP1,IRF8,MSL1,MYLK2,ITGAM,SLC35G1,KCND1,LAMP2,LIMS1,MAT2A,MEF2C,MEIS1,MIA2,MMP16,ZNF92,MYO7A,NDP,CCDC13,NEK1,NINJ2,SLC11A2,NTRK2,TBC1D25,ABCB1,ZFYVE21,GPSM2,STRN3,PSAT1,SCHIP1,ING3,SEPT4,FSD1,PPP1R1A,MASP1,CYBC1,APTX,TMEM104,PIGG,CNTLN,MTMR10,ZIK1,PTPRG,ZNF615,PID1,CCDC40,FAM66C,FIGN,RFX3,RGS4,SUGCT,EXD2,ARMC5,GSTCD,CYB561D1,EPHA10,RPL15,GLDN,HSD11B1L,KCNIP3,RTN1,PRCD,ZFP2,SGK1,PPM1E,CHD9,ANKRD6,BTBD3,SLC6A8,SLC14A1,CDK5RAP2,ANKRD36,LIMCH1,SNCA,FAM219A,NMNAT2,KDM4C,PEG10,ATP10B,POGZ,ZC4H2,CEP68,NUDT10,SYN2,SYPL1,TACC1,EXOC7,TAL1,KIAA0930,CLASP1,SLC19A3,TNS2,CYB561A3,AP4E1,ZNF106,BHLHB9,TP53BP1,ZNF346,METTL3,NUTM2A,DCBLD1,RUSC1,SSBP2,ZKSCAN5,UBTF,GORASP1,WIPF1,LAT2,LGI4,ZBTB14,ZNF708,ZNF74,PCBP1-AS1,SPIRE1,EMSY,VPS35L,PPP1R3F,TMEM63C,CASC15,FAM219B,JMJD1C,TIGD6,FXR1,IFT88,PRRT4,FAM198A" MicroRNA hsa-miR-3136:mirSVR_lowEffct hsa-miR-3136:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-91 6.33E-88 1.33E-90 1.23E-89 262 1655 "VWA5B2,KLHL32,GALNT16,TMCC3,RNF157,ADD1,ADD2,KIAA1211,ESYT2,ZNF608,HECW2,OSBPL1A,ZNF578,ARHGAP20,CDC42BPA,DPP10,EP400,MYH7B,PPFIA4,EPB41L5,LGR5,ZSCAN18,NUMB,TMEM108,SLC4A4,ATP2B2,TTLL9,ADAM15,BBS2,KSR1,ARHGEF7,CASTOR3,MTMR3,SGCE,CACNA1G,CALM1,PTBP2,CAPN3,CAST,SPAG9,LDB2,SCARB1,ZBED1,DCLK1,LOC730101,MAGI1,CDO1,CCPG1,CACNA2D2,CHGB,EPS15L1,CLCN3,MAP4K4,SMARCAL1,CDC42BPB,SNCAIP,CSF1,SUSD5,PDE4DIP,CNTNAP2,SLITRK5,PHF14,CCDC144A,KIAA0408,DOCK4,MATR3,DBN1,ZNF804A,ELMO1,MFAP3L,KIAA0753,RHOBTB1,WDR20,CHRDL1,DNM1,DMTF1,SLC25A18,PDCD6IP,DNM1L,EDN1,EDNRA,CNNM1,RASGRP1,SEMA3D,FAM13A,KMT5B,PAN3,ZNF549,CDKL3,MRPL10,TLR7,EXTL2,MRVI1,CEP78,ZNF589,AMOTL2,MEX3B,IP6K2,PCYOX1,ANKFY1,NBEA,SMC2,UFM1,ERGIC3,AP4B1,ZMAT1,MEGF10,GABBR1,GALC,CPLX2,ALDH1L1,NFU1,ADAM28,GHR,LYVE1,RNPS1,SPIN1,RAB30,CBX1,LUZP2,GNAL,GPD2,TDRKH,MCHR1,GPER1,PCLO,ATP2B1-AS1,GRB10,ADAMTS13,ZNF496,RASSF8,GABARAPL2,SYNPO,ZDHHC15,EID2B,IDH3B,SHISAL1,KPNA5,LAMP2,MAPT,CHIC1,MEIS1,KITLG,MKLN1,MN1,MYO6,ZNF862,NF1,NFYA,IGSF11,GLIPR1L2,PDE4A,CCSER2,PRIMPOL,ANKRD16,SCHIP1,ING3,MINDY2,PPP3CC,RASGEF1B,PRKACB,CEP41,EPDR1,PIGG,PTN,PTPRD,PTPRE,PTPRG,ZNF615,TUG1,PPP2R3C,PID1,SH3TC2,RASGRF1,RASGRF2,RADX,RDX,TRIM68,SLC25A36,ROBO1,RORB,EPHA10,RPL15,ARMH4,FBXW7,ZC3H14,TNFRSF19,GALNT10,SGK1,ZFP30,FAM102A,PPM1E,AMBRA1,FHOD3,SEC31A,DHX30,FAM214B,SLC8A1,ZNF667,RCOR3,MBD5,FAM126B,MYO16,DOP1A,BDP1,SOX11,UHRF1BP1L,SPP1,KDM4C,NFASC,ZC4H2,SS18,SULF2,SYN2,MTCL1,EXOC7,ADGRL3,KLHL4,ZEB1,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,HIF3A,ZFPM2,ITGB3BP,ZNF106,TLR4,RIMBP2,RASD2,SYNPO2,TRO,PPIL6,TSC1,ZKSCAN5,SGK3,FLRT2,CCDC136,KCNK12,ZBTB14,ZNF24,ZNF45,SPHK2,TMEM237,SPIRE1,SMARCAD1,SLC38A1,HPS4,GAL3ST3,ITM2C,PARP11,EPM2A,RGS7BP,SMIM8,JMJD1C,RNF170,KLHDC1,FRMD6,LAS1L" MicroRNA hsa-miR-362-5p:mirSVR_lowEffct hsa-miR-362-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-91 7.65E-88 1.61E-90 1.48E-89 286 1959 "KCNH8,ABR,SYN3,ABHD6,NCKAP5,GALNT16,TMCC3,GALNT13,ESYT2,MTUS1,CC2D2A,ADGRF5,CEP126,ABCD2,CARNS1,LRCH2,EPB41L5,PHYHD1,ZFYVE28,ARNTL,PLA2G4C,CADPS,ZBTB10,NCOA1,TMEM108,EIF4G3,ATP6V0A1,BACH1,BCHE,MIR9-3HG,PROM1,FUBP1,KALRN,CAMK2A,VXN,CARS,CBR1,RGN,LOC730101,MAGI1,NUMBL,MS4A7,B4GALT6,CLCN3,QKI,COL4A5,LETMD1,SLC4A8,COX4I1,BAG4,MYRIP,CPS1,SEC31B,C2CD2,CS,FAM169A,RUBCN,CCDC144A,DCAF8,ZNF337,MATR3,DGKB,AIF1L,ELMO1,SV2B,GRIN3A,DMD,NR1D2,DTNA,DNAJB6,E2F5,E2F6,ANKRD46,FCF1,FRY,PHF20L1,EGFR,MBNL2,KMT5B,AASS,PLEKHA1,PCOLCE2,PAN3,RCAN2,ERCC2,MRPL10,ETV1,ANKMY1,MRVI1,F5,REEP2,ARMCX1,CEP78,ZNF589,SEC24B,FER,FGF1,FGF12,POLK,UBE2E3,MEX3B,FOXF2,PCYOX1,VTI1B,SYNCRIP,FLT1,C2orf88,WDR83,APOPT1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,ZMAT1,DENND2A,IP6K3,ZNF559,DISC1,IGSF5,NEU3,GFRA2,MALT1,GLI2,DCLK2,GPR12,STMN2,GRIA2,PRDM5,RNF165,AP4S1,ATOH8,RASSF8,HAS2,ATXN2L,HNF4G,MSL1,IDH3B,C2orf72,RBPJ,NIM1K,ITPKB,KTN1,LAMP2,HECTD2,SMAD9,MAP6,MATN2,MBD1,MBNL1,TM6SF1,LRP1B,MEIS1,KCTD6,MIA2,MITF,BLOC1S2,MYT1,NEFH,NEK1,NFE2L2,NOVA1,SLC11A2,NUCB2,GLIPR1L2,CNTN3,DPY19L2P2,PDE1C,PDE3A,GPR173,SERPINI1,FAM218A,KCTD15,PLXNB1,ING3,RETREG2,DRAM2,PPARA,DCHS2,SAMD9,ZIK1,PTPRG,TMEM145,TUG1,PPP2R3C,FAM66C,SH3TC2,ENOX1,ZNF493,OXR1,RASGRF2,RBBP8,TRIM68,RET,FIGN,RFX3,RGS3,RIC8B,PGBD4,ZC3H14,GLDN,LRRK2,RPS20,ABCA11P,ZNF568,SCP2,SCAF8,SH3GL3,FERMT1,DZIP1,PKNOX2,SLC6A11,CCDC88A,SLC11A1,BTBD7,CPEB4,RCOR3,IFT122,CABCOCO1,FAM126B,BDP1,ZHX3,SP4,NMNAT2,MYCBP2,DBNDD2,CDK19,TSPYL2,SPART,POGZ,THSD1,ELOVL4,ARHGEF9,VPS13A,SYN1,SYN2,CAMTA1,TAF9,EXOC7,IQCE,DMXL2,SATB2,RPGRIP1L,HIF3A,FAM200B,PMS2CL,MTMR14,HEY1,ACTR6,RIMBP2,R3HDM1,C9orf85,WBP2,TRIO,STXBP4,TRPS1,PPIL6,UBE3A,GORASP1,BCL2L13,VAV1,RICTOR,XPO1,ZIC2,TRIM9,ATP6V0E2,LYPD6,ZBTB38,TMEM237,ANKS1B,SMARCAD1,STOX2,RNF103,ADAMTS9,FAM47E,WNK2,PDSS2,EPM2A,RGS7BP,FAM13C,HNRNPA3,MSRB3,KLHDC1,IFT88,NETO1,FAM198A,SPATA13" MicroRNA hsa-miR-31:mirSVR_lowEffct hsa-miR-31:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-91 8.83E-88 1.85E-90 1.70E-89 271 1769 "VWA5B2,ABR,ACADM,ACHE,ADCY6,UNC5A,KIAA1211,AP2A2,INTS2,TBC1D14,KIAA1324,CC2D2A,AK2,ARHGAP20,PCDH10,UNC79,PDZD4,AMT,ZFAT,OGT,PI16,CCDC146,LCORL,PRX,MADD,SPTBN4,STK33,CCDC74A,SLC2A11,KSR1,SYNJ2,SCAPER,CALM1,CAMK2G,VXN,HIP1R,CERS5,USP2,ENTPD2,LRBA,DCLK1,LARGE1,SOCS6,NDST3,HECTD1,FHL5,SUMF2,COL9A1,COX4I1,SMARCAL1,ZNF521,CREM,NCOR2,ARHGEF10,CSNK1E,FAM169A,DZIP3,ERC2,RUBCN,MYADM,CENPL,KIF26A,MAML1,TMEM170A,BRINP1,ARMCX4,YTHDC1,ZBTB24,FBXL5,DDX46,WDR20,DMD,CPEB2,DMTF1,SLC12A6,DNM1L,E2F5,EDNRA,HEYL,EIF5,PLEKHA1,C3orf18,EPB41,ENPP6,GPHN,SLC43A2,SPEG,MRPL37,MRPL10,VPS26C,F8,TAOK3,STRADA,SLC9B2,SUCO,UBE2E3,SEC23B,FOXF2,IP6K2,ANKFY1,NOP56,C2orf88,FAM49B,CELF1,CGREF1,STAU2,ERAP1,SEPT9,INPP5K,KIAA1841,GCK,ADAM28,TXNL4A,STARD3,MAP7D2,GNAO1,GPT2,WDFY3-AS2,PRRC2B,GPD1,STON1,GRB10,GRIA2,DIDO1,GSTM5,GSTT2,AP4S1,RNFT2,ATOH8,MUM1,PADI2,ZHX1,ATXN2L,HLF,SYNPO,ICA1,GAREM2,KCNN2,KCNN3,LINC00634,STXBP5,KTN1,CAMK2N2,STMN1,LIFR,MAP2,MAP6,MARK1,MAT2A,MEIS2,PPM1L,MMP16,DBNL,ADAM22,PTOV1,MT1M,NBL1,NEK1,NTRK2,NTRK3,OGG1,PCDH8,PCDH9,SEMA5B,FAM216A,PMP22,TRHDE,STRN3,RETREG2,FA2H,PPP1R1A,PPP3CA,PRKAB2,PRKAR1B,MAPK10,GRAMD1C,CNTLN,ANKHD1,TMEM260,ZSCAN32,EML5,PTPRE,PTPRG,PEX2,TMEM231,OXR1,RASGRF1,RASGRF2,RBBP6,ZDHHC14,RDX,TRIM68,SLC25A36,KIRREL1,SNX22,EMID1,KCNIP3,S100B,SCP2,FOXRED1,SGK1,SH3GL3,HKDC1,AMBRA1,CCDC92,SLA,PEX26,LIMS2,TRIM67,SLC11A1,CDK5RAP2,INAVA,SNRPN,RBM34,SOX11,MYCBP2,ZC3H13,SPTAN1,IQSEC2,SPART,NFASC,ATP10B,ITPRID2,MPRIP,TTBK2,RGL1,ADHFE1,STX1A,SEPT3,RHBDL3,PLCB1,SYN2,TACC1,TAL1,SIN3B,DMXL2,NAT16,PUM2,ITGB3BP,ARL10,ERCC6L2,PRRT1,CHST5,RGMB,RUNDC3B,NEIL2,RUSC1,TSC1,TTTY15,HSPBP1,CLHC1,PLEKHH2,TBC1D15,WRN,CLDND1,GUSBP1,PCDH20,ZBTB14,TCEAL7,POLR3H,DPYSL5,SLC30A3,STOX2,RNF103,TMEM178A,AMN1,DOCK8,RTN4,FXR1,LAS1L,SPATA13" MicroRNA hsa-miR-583:mirSVR_highEffct hsa-miR-583:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-91 9.38E-88 1.96E-90 1.81E-89 244 1442 "KCNH8,KDM5D,KLHL32,ADCY6,ADRA1D,ADRB2,DPY19L2P4,KLHL13,OSBPL6,CC2D2A,CEP126,AMPH,OGT,ANK2,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,FAM131A,MARCH3,ZBTB10,RASL11B,CCAR2,ATP1B3,N4BP2L1,NRP2,BLM,KSR1,SYNJ2,NAE1,CACNA1B,THSD7A,SLC25A14,NFS1,CERS5,MTMR7,SEPT7,TIGD7,RCBTB2,TAOK2,LHX2,EPS15L1,CLCN3,FBXO7,QKI,CNGA3,IQCK,PCYT1B,ABI3BP,BAG4,ENTPD4,ANKRD44,SNCAIP,CSF2RA,SEC24C,OSBPL3,PDE4DIP,PHACTR3,SLITRK5,PHF14,RIMS2,DCAF4,USP6NL,CYBB,DOCK4,KATNAL2,ZFYVE16,EARS2,ZNF337,DGKB,DBN1,YTHDC1,ELMSAN1,SGSM2,FAM107B,DNM1,DNAH9,NR1D2,DTNA,ABCC5,EBF1,EDN3,FSD1L,EIF5,ING4,C8orf37,CALCRL,PAN3,EIF1,EPB41L2,RCAN2,IGSF6,PIPOX,SIRPB1,EXTL2,F8,FAM198B,PTK2B,FDFT1,ZNF589,GORAB,FGFR1,FHL1,IP6K2,FLT1,C2orf88,NBEA,SPECC1,FAM49B,ERGIC3,FYB1,FYN,FAM120B,GALC,ZNF234,SIGLEC8,C15orf41,DISC1,ADAM28,MMADHC,MALT1,BRD8,KDM2B,CNTRL,KAT7,PSIP1,GABARAPL2,CPT1C,HSPA1L,IRF8,MSL1,IGF1,IL6R,IL6ST,INPP1,FAM69A,NME9,KCND2,KIF5A,KIT,LIMS1,SYTL4,HECTD2,NCOA7,LYPLAL1,MAT2A,MBNL1,TM6SF1,LRP1B,MEST,MMP16,MN1,TAGLN3,MXI1,NF1,CNOT4,NOVA2,P2RY1,CNTN3,PCDH9,PDE1C,PIK3R1,PCDH18,PURG,PSAT1,LRRN3,PPP2R5E,CEP41,PRPSAP2,VPS13C,CNTLN,PTK2,ZSCAN32,PTPRD,NWD1,OXR1,RASGRF1,UBR7,MRPS18A,EXD2,ABCA11P,KCNIP1,ZNF568,RYR3,S100B,LRFN5,SCN7A,FOXRED1,KIF27,SH3GL3,KIF16B,SHMT2,CNKSR2,NLGN1,ANKRD6,PPP4R3A,KANSL3,SLC11A1,KBTBD4,SLC12A2,NAPB,ATF7IP,CPEB4,INAVA,TRERF1,BDP1,DOK5,KDM3A,UHRF1BP1L,CLSTN2,ITPRID2,ERBIN,RGL1,KLHL7,FAM208A,CUX2,TRIM2,RPGRIP1L,PCDHGA4,OBSL1,ARHGAP9,PCDHA5,FRYL,ZMAT3,ZNF34,TIAM1,ERCC6L2,TRPS1,DCBLD1,TSN,SSBP2,TTC3,UBE3A,MGAT5B,XRCC4,ZFP37,ELFN1,UPF3A,NAV3,SLC17A7,WNK3,RGS7BP,DNAH10,KAT6A,JMJD1C" MicroRNA hsa-miR-3170:mirSVR_lowEffct hsa-miR-3170:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-91 1.18E-87 2.46E-90 2.26E-89 260 1635 "KCNH8,EMILIN3,RNF157,ADD2,PWWP2A,KIAA1211,RNF150,ESYT2,BEND6,TAOK1,MARCH4,FAM135A,ZNF687,DPP10,C6orf89,APLP1,UPRT,CPNE5,CDK10,ZBTB10,RASL11B,RIPK1,BACH1,ADGRB2,NRP2,KSR1,BMP7,ARHGEF7,CACNA1I,CACNB4,KALRN,HAP1,CAST,METTL6,MTMR7,LRBA,NUMBL,ASIC3,CHN1,C7orf61,EPS15L1,C4orf33,MAP4K4,LETMD1,COL11A2,SLC4A8,COX4I1,ZFP28,CLOCK,SH2B1,CS,CSF1,SEC24C,ARHGEF10,SLITRK5,UBXN2A,CTH,PUM1,GPSM1,DCAF4,MYADM,GAPVD1,ZNF337,MAML1,AIF1L,YTHDC1,JAKMIP2,ZBTB24,ELMO1,DDX46,POM121,GRIN3A,DPH1,DTNA,FCF1,FRY,SUGP2,ELN,C8orf37,VPS13B,EPB41,RABEPK,RASL12,CLVS1,NSRP1,FCGR3A,GTF2IRD2,FGF1,FGF11,FHL1,PCYOX1,AGAP3,SEMA4D,FLNC,C2orf88,EFCAB2,AKAP3,POMT1,UFM1,PDLIM5,STAMBP,ERGIC3,CGREF1,DLL3,ABLIM2,FAM120B,B4GALNT1,ZNF234,ERAP1,SYT17,LRRC37A6P,GCK,GCNT2,SULT1C4,GFRA2,GGT7,PPARGC1A,MALT1,MSL3,LNX1,LILRB4,ADAMTS13,KAT7,RABL2A,ATOH8,IRAK3,HLF,ELOVL5,ZNF491,ZDHHC15,CPT1C,EID2B,FAM95B1,MYLK2,KNDC1,IL6ST,INPP5B,INSM1,METTL21A,KCNJ16,GATD1,CYP27C1,LAMP2,LIMS1,HECTD2,NCOA7,LSS,CLEC18A,ZNF667-AS1,MAN2A2,MAP6,MBP,CHST6,MEIS1,SCAMP5,XRRA1,ZNF92,MYO7A,ZNF862,NEK1,NOVA1,NRCAM,ZNF827,PCSK1,DUSP26,GPSM2,PCDH18,MAPKAP1,SH3KBP1,LRRN3,NKAIN4,SAMD9,ELOVL2,PTPRD,ZNF793,SH3TC2,RASGRF2,GTDC1,ZDHHC4,MRPS18A,KLHL11,RIC8B,DCUN1D2,PNMA8A,GSTCD,ROBO1,ROBO2,SPIN3,KIAA0895L,SGSM1,STK32B,PTGR2,FAM192A,MAPK12,SCN2B,GALNT10,COPZ1,HKDC1,AMBRA1,CHD9,ST6GAL1,PEX26,KANSL3,SIRT2,SLC12A2,NAPB,BTBD7,SLC22A4,TET1,CDK5RAP2,MYH15,IFT122,ANKRD36,MBD5,KIF13A,SNRPN,TMCC1,KDM4C,PEG10,ZC3H13,IQSEC2,ZBTB43,NFASC,ATP10B,SSTR2,ZC4H2,ZSCAN29,CEP68,ADHFE1,KANK1,ARHGEF9,ANKRD28,TACR1,EXOC7,IQCE,SIN3B,ZFP90,SZT2,SYNE1,NAT16,DOCK9,PCDHB9,PUM2,R3HDM1,TNS1,CDK20,C9orf85,AMACR,UBTF,VIPR2,RICTOR,GUSBP1,ZIC1,ZNF19,ZNF24,DPYSL5,SMARCAD1,ADAMTSL3,IFT88,NETO1" MicroRNA hsa-miR-3140:mirSVR_highEffct hsa-miR-3140:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-91 1.22E-87 2.53E-90 2.33E-89 238 1374 "AS3MT,BRAP,PTCHD1,MTUS1,KLHL13,OSBPL1A,PCDH10,DPP10,LRCH2,LCORL,MAP4K3,PPP4R4,IGDCC4,ZSCAN18,NUMB,N4BP2L1,TTLL9,ADGRB3,CFLAR,PROM1,SYNJ1,ARHGEF7,CASTOR3,SGCE,PTBP2,CAMK2G,CAST,RUNX1T1,PRC1,SLC16A4,CD38,DGKI,CDH2,LRRFIP1,MAGI1,NOG,CHN1,CHN2,CNOT8,NDST3,NRXN3,HECTD1,ARMC8,AKAP6,LETMD1,ABI3BP,TOGARAM2,MYRIP,IGDCC3,SLC35F1,FAM171B,CRMP1,ANKRD44,GDA,LRRC3B,ARHGEF10,OSBPL3,VCAN,KATNAL2,RIPOR2,ARHGAP24,CENPL,LIN54,KCTD8,JAKMIP2,MYEF2,LYPD1,DDX46,SPOCK3,DLX1,HS3ST2,USP3,DNAH9,GOLT1B,E2F5,EBF1,WDPCP,EDN3,FRY,PHF20L1,EGFR,CALCRL,LRRC17,MTSS1L,EPHB1,ERBB2,DENND4A,EYA1,ABCA8,FAM198B,ZNF461,FER,FGF1,FLT1,NOP56,NELFCD,C2orf88,APOPT1,STAMBP,KHDRBS3,SARAF,ZMAT1,ERAP1,ALDH1L1,PCDH17,GLUL,ZNF638,CBX1,ZNF782,FERMT2,ATP2B1-AS1,GRB10,GRIA2,CIT,FAM19A2,COQ10A,RASSF8,UBE2QL1,ZHX1,NEGR1,CELF5,ICA1,MSL1,RBPJ,LRRTM1,KIF5A,STXBP5,KTN1,LAMP2,PAXBP1,HECTD2,LYPLAL1,MBP,EFHB,POC1B,MYO9A,NEFM,NF1,NUCB2,P2RY1,GPR137C,CNTN3,PCDH9,PCSK5,PDE4B,PCDH18,TRHDE,SH3KBP1,PPP2R5E,PRKCB,GRAMD1C,HYDIN,PRPSAP2,RELN,PIGG,PTN,RIPOR1,ZNF493,OXR1,RBBP6,ZMAT4,ERI2,RNASEL,SETD5,CARF,ROBO2,RORB,RPE,NEK11,FBXW7,ABCA11P,ATAT1,KCNIP3,CLIP1,TRAPPC13,ATXN7,SCN7A,HES6,PPM1E,SHC4,SEC31A,ANKRD6,PPP4R3A,DHX30,WDR47,SLC6A8,ANKRD36,LIMCH1,KIF13A,SNRPN,USP33,PDZD2,SOX3,BDP1,HECW1,KDM4C,UNC5B,RBM26,ATP10B,SEPT8,STXBP1,VPS13A,PLCB1,PJA1,CAMTA1,ADGRL3,RPGRIP1L,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,ZMAT3,SLC44A1,NR2E1,ERCC6L2,TMPO,SYNPO2,TSC1,RPL7L1,VSNL1,P2RY12,NPDC1,ZSCAN26,LAMP5,PRTFDC1,VPS35L,GAL3ST3,FIP1L1,AMN1,UBE3B,FRMD6" MicroRNA hsa-miR-628-3p:mirSVR_lowEffct hsa-miR-628-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-91 1.29E-87 2.68E-90 2.47E-89 250 1515 "SYN3,ACADM,CLK4,NCKAP5,FMNL2,CCDC85A,TMCC3,PWWP2A,ZNF608,PCDH19,AK2,HFM1,SPOP,ARHGAP20,AMPD3,ZFAT,OGT,SEMA7A,MAP4K3,PKP4,APAF1,GAS7,UPRT,USP37,PPP4R4,ARRB2,ZBTB10,ATP2B2,ADGRB3,NRP2,CFLAR,ARHGEF7,MTMR2,JAZF1,SGCE,CACNA1I,CA12,THSD7A,KALRN,CCNH,SRSF11,CHGB,B4GALT6,NDST3,NRXN3,TPP1,C4orf33,MAP4K4,CNTN1,AKAP6,COL4A5,AKAP5,SLC4A8,ABI3BP,BAG4,MYRIP,NRG2,SLC35F1,CRMP1,GDA,SNCAIP,VCAN,PHF14,GREB1,DCAF8,DNAL1,PITPNC1,MYEF2,FAM107B,EXOG,RAB39B,CPEB2,PDCD6IP,ECM2,DNM1L,TMTC1,OPTN,PHF20L1,MBNL2,KMT5B,GOLGA7,KCTD3,PLEKHA1,RGS17,PAN3,USPL1,LRRC17,STX2,MRPL10,MRVI1,CLVS1,ACSL4,SCML2,MED12L,OLFM1,SLC37A3,NOP56,EFCAB2,NBEA,TMEM107,APOPT1,UFM1,ST6GALNAC3,GABRA3,GABRG2,B4GALNT1,DISC1,MSTN,PCDH17,LOXL3,LNX1,GSTM5,RNFT2,HLF,SYNPO,HMGCR,HNMT,EID2B,MSL1,TJAP1,SCIN,INSM1,GATD1,IPO5,GPR155,MARK3,MATN2,TM6SF1,LRP1B,MID1,POC1B,MMP16,MPP2,MSR1,THYN1,MYCN,NEXMIF,NCF2,NF1,VWA2,NOVA2,SLC11A2,SMIM11A,NTRK2,OGG1,GPR137C,TREM2,ZFYVE21,GPSM2,FAM216A,PLCL1,PCDH18,PRIMPOL,LRP12,ING3,TATDN3,PPP2R2B,RANBP3L,PRKAB2,PKIA,MASP1,PTN,TMEM260,PTPN13,TMEM255A,SH3TC2,RADX,GAL3ST4,ERI2,SLC25A36,RIC8B,CCDC82,GSTCD,ELP2,EPHA10,RPL15,ARMH4,LRRK2,SAFB,SALL1,SATB1,ATXN2,LRFN5,SCP2,FNIP1,HES6,TNFRSF19,GALNT10,KIF21A,SH3GL3,FRMPD1,KIF16B,FBXO11,FHOD3,CNKSR2,SYBU,NAPB,RCOR3,SNRPN,FAM126B,MYO16,NMNAT2,HECW1,UHRF1BP1L,KDM4C,ITPRID2,CEP68,ADHFE1,ARHGEF9,ADAMTS17,DNAJC9,COBL,C12orf76,ADGRL3,TCF12,SYNE1,DOCK9,PCDHB9,PCDHB4,FRYL,ZFPM2,C18orf54,ITGB3BP,RIMBP2,TPM2,TRPS1,FLRT2,VGF,TBC1D15,RICTOR,KCNT2,TRIM9,ZNF138,ZBTB38,POLR3H,ZNF195,EMSY,EVI5,LINC02210,STOX2,RNF103,FAM47E,UBE3B,PHTF2,ACTR3B,FAM219B,JMJD1C,MSRB3,GAN,CPNE4" MicroRNA hsa-miR-4297:mirSVR_lowEffct hsa-miR-4297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-91 1.30E-87 2.70E-90 2.49E-89 255 1575 "KCNH8,ACHE,KLHL32,TMEM132B,ADCY6,TMCC3,USP31,KIAA1211,SLC24A4,PCDH19,KIAA1324,CC2D2A,ZNF578,ALCAM,CEP126,MARCH4,DPP10,PPFIA4,PHF12,PKP4,CASK,RASL11B,ATP1B3,DPY19L3,RIPK1,LINC00847,CFLAR,SYNJ1,JAZF1,GYG2,GPC2,CACNB4,CABP7,CAMK2A,CAMK2B,HIP1R,PRC1,LDB2,CD86,ARHGEF1,SYNGR3,MAGI1,DLGAP1,CFL2,RAB28,STOML1,PREPL,C2CD2,C1QL2,GDA,CLIP3,SNCAIP,CSF1,LRIG1,SIPA1L1,CST3,PITPNM3,RIMS2,RUBCN,SEC14L5,HDAC9,ARHGAP32,KATNAL2,LIN54,AIF1L,HEPH,KIAA0753,DDX46,SV2B,DNM1,USP3,CDON,DOCK2,DMTF1,DPH1,DPP6,ACOT8,DTNA,EDNRA,ANKRD46,PHF20L1,KMT5B,TMEM35A,EPHB1,RABEPK,ZNF549,DNAJC27,TBC1D16,FCGR1A,CEP78,ZSCAN30,FGF1,FGF12,HPCAL4,AGAP3,NELFCD,EFCAB2,JKAMP,TMEM107,UFM1,ST6GALNAC3,HHIPL1,MPP6,RAPGEF6,ACSS1,IGSF5,ALDH1L1,GHR,MALT1,ZNF276,GLI2,GLYR1,MSL3,KDM2B,DCLK2,WDFY3-AS2,FUT10,MCHR1,GPR37,LINC01089,CLASRP,KAT7,ZBTB49,ATOH8,HAS2,TOX2,FRMD5,GABARAPL2,AGBL5,CPT1C,ZNF546,LRRCC1,DISP2,SCIN,IL6R,INPP5B,ITPKB,KCND2,KCNK3,KCNN1,KIT,LAMP2,MAPT,KCTD6,XRRA1,MOV10,HNRNPM,NUCB2,TBC1D25,OGG1,ZNF827,PRTG,PFKFB2,PFKFB3,SNX10,PNMA3,EPB41L4B,PPARA,PPP1R1A,PPP2R5E,PRKAB2,PRKACB,DIRAS2,MASP1,VPS13C,PTPRD,PTPRN2,ACSM5,NKAIN1,TUG1,TMEM231,C1orf54,FAT4,NWD1,ROGDI,OXR1,RASGRF2,ZDHHC14,RGS12,ZFHX4,ZNF532,CARF,CYB561D1,CCDC102B,EPHA10,MAP6D1,HUNK,ST6GALNAC6,KCNIP3,RYR3,SCP2,GALNT10,MRAS,RASA3,SH3GL3,FRMPD1,CPEB3,MYO18A,FBXO11,FNDC3A,PPP4R3A,PKNOX2,SLC6A11,SLC8A1,SLC11A1,SMARCC2,CDK5RAP2,MBD5,KIF13A,SNRPN,TMCC1,NMNAT2,ZC3H13,NFASC,CLSTN2,ZC4H2,ZSCAN29,STAC2,STXBP1,SYN1,ANKRD28,SLC37A2,SYT5,EXOC7,ATMIN,RPGRIP1L,TCF12,PCDHB10,OBSL1,TNS2,FRYL,HIF3A,PMS2CL,AP4E1,TMEM9,TP53BP1,SYNPO2,NEIL2,KCNE5,UBE3A,UBTF,UGT8,OSBP2,PLEKHH2,WIPF1,ZNF781,RICTOR,GUSBP1,PCDH20,TMEM237,AMZ1,URM1,UBE3B,HNRNPA3,SPATA13" MicroRNA hsa-miR-26b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.58E-91 1.44E-87 2.97E-90 2.74E-89 279 1874 "ABCF1,ACADM,KDM5D,MTA3,ZNF608,AGT,NME5,KIAA1324,C1QTNF1,SRPX,FAM135A,EP400,MAP4K3,APBB2,CDC14B,MADD,ARRB1,RGS20,MARCH3,ATP1A1,ATP1A3,ATP2A2,MPDZ,BCHE,BID,NAE1,CACNB4,CH25H,LDB2,USP6,SLC16A4,DGKI,SEPT7,CDC25B,ZBED1,CRLF1,RCBTB2,SOCS6,ABCG2,FHL5,CNTFR,ARMC8,COL4A5,AKAP5,GAL3ST1,NSL1,CLOCK,SUSD5,PDE4DIP,CST3,PLXNA4,CTH,GREB1,CCDC144A,KIAA0408,DCAF8,MATR3,PITPNC1,ARMCX2,ZBTB24,MYEF2,GSDME,SNAP91,SACS,SV2B,TMCC2,FAM107B,USP3,DTNB,ANKRD46,EGR3,PLXNC1,EIF4G2,EIF5,PLEKHA1,RGS17,PCOLCE2,DCTN4,HSD17B14,TUBD1,LRRC17,IGSF6,ZNF549,NRN1,FAM198B,RPS6KC1,FCGR1B,CHST15,FKTN,FDFT1,GTF2IRD2,FGFR3,SUCO,SCARA3,FOXF2,PCYOX1,SYNCRIP,NELFCD,FOLH1,FOLR2,FAM49B,CSPG5,GABBR1,GABRA3,GABRB3,ERAP1,INPP5K,GCNT2,TUBGCP4,SESN1,BRD8,GLI2,RAB30,TNRC6A,RAB40B,GP1BB,CNTRL,TPPP,ANKRD36BP1,GRM8,GSTT2,ZBTB45,FICD,SLC2A6,HAS2,ATXN2L,DHX35,HSF2,HSPA1L,EID2B,IFI16,SHISAL1,IGF1,IL12A,INPP5B,KCND1,KCNF1,KCNN2,KHK,KIFC3,RAMP2-AS1,L1CAM,LIG4,LSAMP,PACRG,SMAD1,MAT2A,MATN3,LRP1B,MEF2C,ZNF680,DBNL,BLOC1S2,MT1M,N6AMT1,TAGLN3,SAMD14,MXI1,ZNF862,HNRNPM,NCAM2,NFE2L2,CNOT4,PCBP3,NUCB2,PCSK1,CDK18,PDE4A,PDE4B,PFKFB3,CCSER2,PLCB2,SLC25A23,ZNF426,PMP22,MAPKAP1,PSAT1,POLG,POLR2F,PKIA,DCHS2,CNNM2,NDUFS7,VPS13C,WDR25,CNTLN,ELOVL2,PTPRO,QDPR,MARCH1,RAD51D,NWD1,ROGDI,ENOX1,RASGRF1,ZMAT4,TRIM68,ERI2,MORC4,RGS3,SLC25A36,RNASE1,SUGCT,DCUN1D2,SETD5,ALG9,CCDC25,RORB,ARMH4,MCMBP,ATAT1,RYR3,TRAPPC13,RMI1,SAFB,SALL1,SCP2,SMPD3,CHD9,FBXO11,PPP4R3A,DHX30,KANSL3,ZKSCAN3,SNRPN,TMCC1,FAM126B,SOX3,SP4,TEX2,ERC1,ZNF423,CDK19,PBLD,CLSTN2,ERBIN,DIP2A,STX1A,ZC3H4,SUPT5H,SYNE2,ASTN2,TAF9,DNMBP,ALG1,KIAA1107,AGTPBP1,SMG6,DMXL2,TCF12,SYNE1,PHF24,USP32P1,TNS2,PCDHA6,KHDC1,ZFPM2,NACC2,ICAM5,ASXL3,TLR4,NR2E1,NR2C2,TRPS1,SSBP2,UBE2H,VAV1,TOM1L2,ZNF23,ZBTB38,ZNF195,MAP3K12,EMSY,HPS4,NELFE,PARP11,PDSS2,DPF3,ST8SIA2" MicroRNA hsa-let-7g-5p:TargetScan hsa-let-7g-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7f-5p:TargetScan hsa-let-7f-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7a-5p:TargetScan hsa-let-7a-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7c-5p:TargetScan hsa-let-7c-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7e-5p:TargetScan hsa-let-7e-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-miR-98-5p:TargetScan hsa-miR-98-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7b-5p:TargetScan hsa-let-7b-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7i-5p:TargetScan hsa-let-7i-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-let-7d-5p:TargetScan hsa-let-7d-5p TargetScan 2.61E-91 1.46E-87 2.97E-90 2.74E-89 191 873 "PLEKHH1,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,CACNB4,CALM1,CAPN3,RUNX1T1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,DAPK1,DNAL1,B3GAT3,MFAP3L,GRIN3A,DMD,CPEB2,DPH1,ARRDC4,DUSP9,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,CEP85L,APC2,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,MEGF11,GALNT15,GALC,C15orf41,GATM,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,CNTRL,CACFD1,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,IL6R,KLHL23,KIF2A,KPNA5,HECTD2,CHIC1,MEF2C,MEIS1,MEIS2,MYCN,NEFM,NME4,NOVA1,GPR137C,KCTD15,PPP3CA,PRKAB2,PKIA,GDPD1,CNNM2,PTPRD,RDX,DPF2,FIGN,KCTD17,DCUN1D2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,CSRNP3,SCN8A,FNIP1,SEC14L1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,PDSS1,PRR18,FAM155A,RICTOR,PCDH20,CRB2,REEP1,CADM2,FZD3,RNF170,GAN" MicroRNA hsa-miR-378:mirSVR_lowEffct hsa-miR-378:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.09E-91 1.73E-87 3.51E-90 3.23E-89 261 1650 "CLK4,SYS1,KDM5D,CCDC85A,TMCC3,ADD2,ADORA1,ADORA2A,RNF150,PTCHD1,MTA3,AP2A2,PCDH19,C1QTNF3,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,APBA2,KCNAB2,VAT1L,PPFIA3,SPTBN4,ARNTL,MARK4,NUMB,DNAJC27-AS1,KSR1,GYG2,CACNA1G,RAB29,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,VXN,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,SOCS6,MYL6B,ABCG2,CNGA3,FHL5,IQCK,FAM149A,COL4A5,ABI3BP,CLOCK,HAPLN1,CRYM,SNCAIP,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,ARHGAP32,HDAC4,INTS1,IST1,DGKG,SPATA2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLX1,RAB39B,DMTF1,PDCD6IP,EDN1,RASGRP1,SUGP2,MBNL2,IRAK4,PLEKHA1,TMEM35A,VPS13B,EPB41,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,ZSCAN30,SEC24B,MED12L,SUCO,PCYOX1,AGAP3,PSD2,ZBED3,APOPT1,GALC,RAPGEF6,IP6K3,DISC1,INPP5K,SRCAP,ADAM28,GGTA1P,ZNF638,CBX1,DCLK2,CLASRP,BVES,IRAK3,SYNPO,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,IL6R,TMEM240,KCND1,KCNN3,L1CAM,HECTD2,MAT2A,AQP11,MEF2C,AFF1,MSR1,PTOV1,MXI1,MYO7A,RTL5,ZNF862,HNRNPM,NCF2,VWA2,NOVA1,DNHD1,NTRK3,PCDH9,PDCD2,PDE4A,PDE1B,TMOD2,PFKFB4,NLGN3,ZNF655,CCSER2,XRN1,SLC25A23,PPARA,PPM1B,PPP3CA,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,PEX2,SUSD4,NWD1,RAP1GDS1,RASGRF1,ERI2,PRIMA1,KCTD17,CARF,GSTCD,PCMTD2,SNX22,RPL15,SPIN3,KIAA0895L,GLDN,TCP11L1,ABCA11P,AP1AR,MAPK12,ATXN2,PEAR1,CASC3,ZNF821,SH3BP2,ANKRD6,EPN2,PKNOX2,ARHGEF40,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SSTR1,LARP4,APOM,SEPT8,ADHFE1,STX1A,ARHGEF9,SYN2,ANKRD28,MMS19,MCF2L,DNMBP,FBXW11,SIN3B,TCF12,TEK,FAM200B,ZNF34,SLC44A1,ARL10,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,ELP5,AMACR,DCBLD1,RUSC1,KCNE5,CLHC1,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,KCNT2,LYPD6,SH3GLB2,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,FAM198A,JPH3" MicroRNA hsa-miR-185:mirSVR_highEffct hsa-miR-185:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.18E-91 1.78E-87 3.60E-90 3.32E-89 235 1342 "VWA5B2,KCNH8,CLK4,KDM5D,NDRG3,ADD2,PTCHD1,KLHL13,ZNF578,SPOP,PCDH10,ZNF687,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,PLA2G4C,ATP1A3,TTLL9,BACH1,ADGRB1,ADGRB2,CFLAR,MTMR2,THSD7A,KALRN,PTBP2,SLC25A14,VXN,LDB2,USP2,MTMR7,SYNGR3,DGKI,SRSF11,LHX2,CPNE6,PPT2,CNGA3,PCYT1B,ARMC8,AKAP6,SUMF2,COL9A3,SLC4A8,ZFP28,SLC35F1,PREPL,GDA,ABCG1,OSBPL3,CSNK1G3,PDE4DIP,UBXN2A,USP6NL,TCAF1,RIPOR2,DCAF8,TBC1D5,DGKB,PITPNC1,SPATA2,KLHL3,ZC3H11A,SV2B,CHRDL1,DMD,DNM1,DTNA,EBF1,SEZ6L2,FRY,PHF20L1,APH1A,EBI3,ING4,TMEM35A,EIF1,RRAGB,DLC1,RACK1,ST3GAL6,POLR1B,POLK,SUCO,EFCAB2,STAU2,ABLIM2,GABRA3,GALC,DISC1,INPP5K,GATM,TUBGCP4,BRD8,TOX3,MSL3,STARD3,ZNF638,KDM2B,DCLK2,PRUNE2,CCDC184,PCLO,GRIA2,PLCD4,SERP2,FAM19A2,KAT7,GSTT2,SOX21,FAM222A,RASSF8,UBE2QL1,PACSIN2,VSIG4,ACOT7,HMGCL,ZNF678,INPP5B,LRRTM1,KCND1,KCNN2,KCNN3,CYP27C1,MAP2,MAP4,MAT2A,MEIS1,SRSF12,MSI1,MYO9A,RTL5,NINJ2,GLIPR1L2,PCDH9,CDK18,PDE1C,CCSER2,PLCB2,PRIMPOL,PRKACB,WDR25,CNTLN,PTPN13,PTPRE,QDPR,FAM66C,FAM184A,ZCWPW1,RDX,TRIM68,DPF2,PRRT2,MORC4,SLC25A36,SETD5,KLHDC8A,CARF,LRRK2,ABCA11P,ATAT1,ZNF568,TRAPPC13,FAM192A,ATXN2,LRFN5,TNFRSF19,SH3BGR,MYO18A,ANKRD6,BTBD3,SLC8A1,CDK5RAP3,SLC11A1,CPEB4,ZKSCAN3,SMARCC2,SNAP25,KDM4B,HECW1,SPTB,DDN,CLASP2,CLSTN2,SSTR2,ZC4H2,ELOVL4,PHLDB1,ZC3H4,VPS13A,SYN1,TMEM150C,ASTN2,TPCN2,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,AP4E1,CDH22,GALNT17,MTMR14,NPL,CHST5,ELP5,TSN,CA14,TSC1,SSBP2,TTC3,RPL7L1,UBE2H,OSBP2,MGAT5B,WIPF1,NPDC1,CELF4,LAMP5,MEIS3,SLC30A3,HPS4,MDH1B,URM1,SLC17A7,PARP11,KAT6A,KLHDC1,IFT88,NETO1" MicroRNA hsa-miR-1260:mirSVR_lowEffct hsa-miR-1260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-91 1.91E-87 3.86E-90 3.55E-89 273 1800 "ASPHD1,ABHD6,TMEM132B,GALNT16,GALNT13,LRFN2,TAOK1,UNC79,SYT13,PDZD4,OGT,SEMA7A,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,PHYHD1,VAT1L,AQP6,SEMA4G,SPTBN4,ARRB2,MARK4,TMEM108,ATP2B2,ZNF583,BBS2,CFLAR,BTK,MTMR3,CACNA1I,CACNA1G,CA4,CACNB4,KALRN,PRC1,ARHGEF25,CBLN1,KRIT1,P2RX6,CDC25B,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,PLEKHB1,TAOK2,ARHGAP22,LHX2,MAP4K4,ARHGEF6,COL4A5,SUMF2,ZNF385A,ANKRD44,NCOR2,ABCG1,RGS6,LRIG1,ARHGEF10,OSBPL3,VAC14-AS1,CST3,PLXNA4,SLITRK5,GREB1,RIMS2,RUBCN,CYBB,RIPOR2,ARHGAP24,DCAF8,RASSF2,LIN54,SPOCK2,AIF1L,GIT2,ARMCX4,ELMO1,C2CD2L,GUCD1,TMCC2,ZNF582-AS1,USP3,NR1D2,CDON,DOCK2,DTNA,DTNB,EDNRA,YAF2,CELSR3,KMT5B,EMX2,COQ7,LRRC17,RASGRP2,MTSS1L,EPHB1,SPEG,ETV1,TLR7,SIRPB1,EZH1,NRN1,CORO2B,FCGR1A,FCGR3A,PPP1R1B,SLC9B2,POLR1B,FGF14,FHL1,FLT1,CAMKK2,ATP2C1,ERGIC3,ABLIM2,TVP23A,MEGF11,GABBR1,GABRA3,GAD1,RAPGEF6,SIGLEC8,ALDH1L1,GGT7,ZNF276,GLUL,DCLK2,LILRB4,TMEM121B,GRIA2,PLPP7,ADAMTS13,RNF165,BVES,PSIP1,NCKAP1L,ARHGAP36,VSIG4,ELOVL5,AGBL5,HNF4G,USP51,HSF2,CELF5,IRF8,MSL1,MYLK2,ITGAM,KCND1,KIF5A,STXBP5,LAMP2,LIMS1,MAT2A,CHIC1,MEF2C,MEIS1,MIA2,MMP16,ZNF92,MYO7A,NDP,CCDC13,NEK1,NINJ2,SLC11A2,NTRK2,TBC1D25,ABCB1,ZFYVE21,GPSM2,STRN3,PSAT1,SCHIP1,ING3,SEPT4,FSD1,PPARA,PPP1R1A,MASP1,CYBC1,TMEM104,CNTLN,MTMR10,PTPRG,ZNF615,PID1,CCDC40,FAM66C,SH3TC2,FIGN,RFX3,RGS3,RGS4,SUGCT,EXD2,GSTCD,CYB561D1,EPHA10,RPL15,SPIN3,GLDN,RTN1,ATXN2,PRCD,ZFP2,STUM,SGK1,CHD9,ANKRD6,BTBD3,SLC14A1,ANKRD36,INAVA,LIMCH1,DOP1A,NMNAT2,KDM4C,PEG10,ATP10B,POGZ,ZC4H2,CEP68,NUDT10,SYPL1,TACC1,EXOC7,TAL1,KIAA0930,CLASP1,SLC19A3,TNS2,CYB561A3,AP4E1,ZNF106,BHLHB9,TP53BP1,ZNF346,METTL3,NUTM2A,DCBLD1,RUSC1,SSBP2,ZKSCAN5,UBTF,GORASP1,BCL2L13,WIPF1,LAT2,LGI4,ZBTB14,ZNF708,TRIM9,ZNF74,SPIRE1,EMSY,VPS35L,PPP1R3F,ITM2C,TMEM63C,FBXO36,CASC15,FAM219B,JMJD1C,TIGD6,FXR1,IFT88,PRRT4,FAM198A" MicroRNA hsa-miR-607:PITA hsa-miR-607:PITA_TOP PITA 3.61E-91 2.02E-87 4.07E-90 3.75E-89 197 934 "XKR4,KLHL32,PTCHD1,ZNF608,PCDH19,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,CDC14B,ZFYVE28,ZBTB10,NCOA1,BLM,SYNJ1,MTMR3,WASF1,LDLRAD4,CACNA1A,PTBP2,CLDN10,KRIT1,ARHGEF2,LONRF2,CLGN,CFL2,SRSF11,CNOT8,SLIT2,CLTC,QKI,CNR1,CNTFR,ZNF521,CREM,HAPLN1,ANKRD44,CLIP3,LRRC3B,CSNK1E,PHACTR3,SLITRK5,ERC2,APPL1,RIMS2,KIAA0408,KIF26A,IST1,DBT,JAKMIP2,MYEF2,FBXL5,ZC3H11A,DDX46,RHOBTB1,SPOCK3,DMD,DYNC1I1,NR1D2,DPYSL2,PDCD6IP,MAMLD1,GOLT1B,FRY,YAF2,MBNL2,EIF4G2,TENM1,PLEKHA1,EPB41L2,GPHN,ERBB4,EXTL2,KATNAL1,MED12L,SUCO,MEX3B,FOXO3,CELF1,FUT9,CHL1,RAPGEF6,IQGAP2,MSTN,PCDH17,TCERG1,SPIN1,TNRC6A,GNAO1,PRRC2B,FUT10,GPR34,GPR37,PCLO,GRIA2,CIT,FAM19A2,PSIP1,MIER3,NEGR1,IGF1,RBPJ,KIF2A,MARK1,MEIS1,AFDN,MN1,MSI1,HS6ST3,NEXMIF,HNRNPM,NCAM2,ZC3H12B,OPA1,PRTG,PDE3A,PDE4D,ENPP2,PDPK1,GNG2,CCSER2,PURG,MAPKAP1,PPP2R5E,MAPK10,TMEM260,PTPRD,RBBP6,FIGN,PBRM1,ZFHX4,ZNF532,SETD5,ROBO1,ATP8B4,CLIP1,NCBP3,AP1AR,KIF21A,CHD9,FBXO11,FNDC3A,NLGN1,BTBD3,SEPHS1,SLC8A1,TRIM67,SLC12A2,NAPB,COA1,FAIM2,PDZRN3,SOX3,DOK5,ZHX3,SP4,PEG10,ZNF423,ARHGAP26,LMO3,CLASP2,LARP4,ERBIN,ELOVL4,PRRC2C,PLCB1,SYN2,SYPL1,CAMTA1,TCF4,SATB2,TCF12,FRYL,DICER1,AP4E1,SLC44A1,RIMBP2,SYNPO2,STXBP4,TRPS1,FLRT2,USP1,TBC1D15,WIPF1,XPO1,ZIC2,ZNF711,KCNT2,REEP1,SMARCAD1,SLC17A7,FAM13C,HNRNPA3,PHTF2,MSRB3,ST8SIA2" MicroRNA hsa-miR-570:PITA hsa-miR-570:PITA_TOP PITA 3.93E-91 2.20E-87 4.42E-90 4.07E-89 205 1016 "KCNH8,ELFN2,ADCY6,ADRB2,INTS2,PCDH19,HACE1,SEMA6A,GPRASP2,AMPH,DPP10,MAP4K3,GAS7,TMEFF1,ATP2B2,ADGRB3,NAE1,SCAPER,CACNB4,CALB1,CAMK2A,CAMK2G,SPAG9,DCLK1,L3MBTL4,CCPG1,CFL2,COPB2,SRSF11,SOCS6,CHN1,CHN2,QKI,RAB26,CNN3,AKAP6,COL9A1,BAG4,MYRIP,ZNF521,IGDCC3,SLC35F1,CREM,AATK,CSNK1E,PLCXD3,FAM131B,IST1,DGKB,GIT2,MYEF2,KIAA0753,DDX46,RAB39B,DMD,USP3,CPEB2,DNAJB6,FRY,OPTN,YAF2,MBNL2,EIF4G2,TMEM35A,PAN3,EIF1,EPB41L2,ETV1,RRAGB,KATNAL1,CORO2B,FGF13,PRKAG2,FOXF2,FOXO3,ANKFY1,AFF2,SMC2,MSANTD4,CHL1,GABRB3,C15orf41,GCNT2,MSTN,AHDC1,SPIN1,TNRC6A,GPD2,GRB10,CIT,PTPRT,PSIP1,MAP4K5,TNFAIP8L3,HLF,SYNPO,HNF4G,HSF2,SMAP1,ZIC5,JAK2,KCNB1,KTN1,MAP2,MAP4,MBNL1,CHIC1,LRP1B,MEF2C,MEIS2,MN1,NEXMIF,MYT1,NEFH,NFIX,CNOT4,OCRL,OPA1,GPR137C,PRTG,PIK3C2A,LRP12,PPP3CA,KANSL1,RELN,WBP1L,SNRK,PTCH1,PTPRD,PTPRG,NKAIN1,RADX,KHDRBS2,RDX,REV3L,RFX3,PBRM1,LGI2,ZNF532,ROBO1,RORB,RPE,SEMA6D,SATB1,ATXN7,CASC3,TRA2B,COPZ1,PPM1E,CPEB3,CHD9,FNDC3A,PKNOX2,SEPHS1,SLC8A1,TRIM67,ELMO2,TET1,LMBRD1,KDM4B,ZHX3,SP4,HECW1,TEX2,ARHGAP26,CDK19,RBM26,CLASP2,LARP4,NSFL1C,NECAB1,PRRC2C,ANKRD12,CAMTA1,TCF4,TRIM2,TCF12,SYNE1,PCDHB7,SIRT1,SLC44A1,ARL10,ERCC6L2,LRRC8A,RIMBP2,R3HDM1,KAT6B,TRPS1,UBTF,XPO1,ZBTB14,ZIC1,TMEM237,ZFAND5,SMARCAD1,CADM2,PRDM10,RGS7BP,FAM13C,RTN4,KLHDC1,FXR1,FRMD6,SOCS4,GAN" MicroRNA hsa-miR-148a*:mirSVR_lowEffct hsa-miR-148a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.17E-91 2.33E-87 4.68E-90 4.31E-89 286 1968 "AS3MT,METAP1D,FMNL2,GALNT13,OSBPL1A,TBC1D14,OSBPL8,CC2D2A,C1QTNF1,SPOP,CEP126,AMPD3,AMT,ZFAT,LRCH2,ANK2,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APAF1,DDO,TNRC6C,ASGR1,TMEM108,SLC4A4,RIPK1,BBS2,MPDZ,RGS9,CACNA1G,CA8,CACNA1A,CALB2,PTBP2,CH25H,RUNX1T1,KRIT1,CBFA2T2,ENTPD6,CDC25B,ZMYM4,CFL2,CHN2,CPNE6,PLAA,FBXO7,MAP4K4,CNTN1,AKAP7,SUMF2,SLC4A8,RCHY1,AHCTF1,CPS1,FAM171B,C2CD2,CREM,AKAP12,HAPLN1,ANKRD44,TRIM69,PDE4DIP,KIAA0040,KIAA0408,DGKG,DNAL1,JAKMIP2,KLHL3,FAM107B,EXOG,GRIN3A,NYAP1,DMTF1,DTNA,DNAJB6,AASDH,EDNRA,EDNRB,YAF2,PHF20L1,MBNL2,AASS,PLEKHA1,CALCRL,DCTN4,EPB41,GPHN,SRRM1,ZNF549,CDKL3,ADGRV1,EYA1,FAM198B,SCML2,CORO2B,DLC1,FCGR1A,CHST15,FKTN,ZSCAN30,FER,FGF12,FHL1,POLK,SUCO,MEX3B,PCYOX1,SMC2,KHDRBS3,MSANTD4,HRASLS5,GABRG1,ZNF274,ZNF559,DISC1,ACSS1,GATM,NFU1,CRCP,HPGDS,TNRC6A,STARD3,ZNF638,KDM2B,WDFY3-AS2,GPR34,GPR37,GRIA2,SERP2,COQ10A,LINGO1,GUCY1A1,MAN1B1,HNF4G,HNMT,ZDHHC15,SMAP1,ZIC5,RBPJ,DISP2,INSM1,KIF2A,IPO5,LAMP2,LMO2,SYTL4,MBD1,CHIC1,LRP1B,SRSF12,KITLG,MITF,MSI1,ADAM22,MYO6,NCAM2,NEFM,VWA2,NTRK2,OXTR,PDE4D,SEMA5B,JAKMIP1,PRIMPOL,LRP12,SCHIP1,ING3,IRX1,PPP3CA,KANSL1,PRKAB2,PKIA,MAPK9,GDPD1,BCAS3,WBP1L,QRICH1,CNTLN,PTCH1,ANKHD1,MTMR10,PTPRB,TUG1,CEP97,ZNF793,NWD1,PRIMA1,PBRM1,ZFHX4,ROBO1,ROBO2,MRAP2,NEK11,RPL15,BAALC,SPIN3,GLDN,TCP11L1,RPS6KA2,ABCA11P,KCNIP1,RTN1,SEMA6D,ATXN2,SCP2,TNFRSF19,SMPD3,TRA2B,COPZ1,HSPA4L,MYO18A,PKNOX2,SEPHS1,SLC8A1,ARHGEF40,SIRT2,SLC14A1,CDK5RAP2,INTS9,ANKRD36,LIMCH1,SNAP25,KIF13A,SNRPN,RBM34,DOP1A,NMNAT2,ZBTB43,RBM26,NFASC,PBLD,SAMSN1,ERBIN,ZSCAN29,JMJD6,SYNE2,TMEM150C,ANKRD28,C12orf76,MMS19,EXOC7,TAL1,FAM208A,FBXW11,KLHL4,SYNE1,DOCK9,USP32P1,TNS2,RNF216P1,ITGB3BP,AP4E1,SLC44A1,ARL10,BHLHB9,ERCC6L2,TMPO,TNS1,TP53BP1,RASD2,NPL,SYNPO2,PPIL6,DCBLD1,ANKRD20A2,RPRM,UGT8,USP1,BCL2L13,CLDND1,GUSBP1,KCNT2,CELF4,ZSCAN26,CADM2,ITM2C,PLSCR4,PDSS2,UBE3B,KAT6A,JMJD1C,TIGD6,RNF170,KLHDC1,FRMD6,RNF146,GAN" MicroRNA hsa-miR-424-5p:TargetScan hsa-miR-424-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-15b-5p:TargetScan hsa-miR-15b-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-195-5p:TargetScan hsa-miR-195-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-16-5p:TargetScan hsa-miR-16-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-15a-5p:TargetScan hsa-miR-15a-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-497-5p:TargetScan hsa-miR-497-5p TargetScan 4.87E-91 2.72E-87 5.40E-90 4.97E-89 211 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,APC,PPFIA3,CASK,ARHGDIA,ATP2B2,BCL7A,NRP2,KSR1,FUBP1,MTMR3,CACNA1I,LDLRAD4,CA8,DDR1,CACNA2D1,LURAP1,CALM1,CAST,RUNX1T1,NFS1,CDC25B,DLGAP2,PPT2,CLCN3,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,KIAA0586,KCTD8,IST1,IP6K1,ARMCX2,ELMSAN1,MYEF2,DYNC1I1,CPEB2,DMTF1,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,EBI3,MBNL2,PLXNC1,PLEKHA1,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,HPCAL4,CINP,PDLIM5,NSG1,GABBR1,PCDH17,GHR,RAB30,FERMT2,ADAP1,GRB10,ADAMTS13,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HMGCR,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KIF5A,KPNA5,LIMS1,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,MYO5A,NDP,NF1,OCRL,PCSK5,PIK3C2A,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FSD1,LRRN3,PRKAB2,RASGEF1B,PKIA,RELN,CNNM2,PTCH1,PTPRD,PID1,FAT4,RBBP6,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN8A,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,NMNAT2,ARHGAP26,NFASC,LHPP,ATP10B,KANK1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ARL10,CBX5,CSMD1,NR2C2,KLC2,RICTOR,EML6,EVI5,GDPD5,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-155*:mirSVR_lowEffct hsa-miR-155*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.43E-91 5.28E-87 1.04E-89 9.62E-89 242 1430 "ACADM,ASIC1,CLK4,NDRG3,TMCC3,USP31,PWWP2A,BEND6,MTUS1,KCTD16,TBC1D14,KIAA1324,TAOK1,ZFAT,CCDC146,SUGT1P4-STRA6LP-CCDC180,PKP4,KCNAB2,APBB2,TNRC6C,USP37,LGR5,CDC14B,SPTBN4,ARNTL,STK33,RIPK1,TTLL9,SEC11C,LDLRAD4,CFAP410,KALRN,ISPD,METTL6,CDC25B,CDH2,ZNF445,FOXN3,AHCTF1,SEC31B,C2CD2,CREM,RBM39,HAPLN1,CSF2RA,PDE4DIP,PHACTR3,APPL1,PUM1,KIAA0408,DOCK4,ARHGAP32,ZFYVE16,TM9SF4,AIF1L,GIT2,DNAL1,MYEF2,GUCD1,SV2B,SPOCK3,NR1D2,SLC12A6,DPP6,DRP2,ARRDC4,DNM1L,SEMA3D,TMTC1,KCTD3,EIF4G2,C3orf18,STX2,ZNF549,MRPL37,F5,SCML2,ZNF589,FECH,FER,FGF12,POLK,MEX3B,IQCG,C2orf88,ZBED3,ATP2C1,STAU2,OGA,ZMAT1,HRASLS5,GABRB3,GAD1,GALC,RAPGEF6,ERAP1,IGSF5,SRCAP,GFER,PCDH17,PPARGC1A,TNRC6A,CBX1,WDFY3-AS2,GPD2,GPR37,GRB10,DIDO1,LINC01089,RNF165,ZBTB49,MAP4K5,FRMD5,MIER3,AGBL5,HNMT,ZNF491,SHISA6,ICA1,IDH3B,RBPJ,GATD1,LIFR,SYTL4,MAN2A2,MAP2,MAP6,MATN3,MBP,KITLG,SCAMP5,ADAM22,MYO6,MYO9A,NFE2L2,NOVA1,SLC11A2,NUCB2,P2RY1,PDE4D,ZNF655,GPSM2,ING3,RASGEF1B,CEP41,PRKCB,MAPK4,PTCH1,SPDL1,PTN,ZSCAN32,TTC13,TUG1,CEP97,SLC25A48,SH3TC2,ZNF493,MSANTD2,RGS3,RNASEL,ARMC5,PCMTD2,TCP11L1,MEG3,STX1B,DGLUCY,SBF1,CSRNP3,TRA2B,ZFP30,SH3GL3,PPM1E,CPEB3,HKDC1,FBXO11,FNDC3A,NUBPL,WDR37,ABLIM3,BTBD3,SLC12A2,ZFP1,SMARCA4,RCOR3,SNRPN,TMCC1,PDZD2,BDP1,FNBP1,SOX11,KDM3A,CDK19,ATP10B,ELOVL4,SEPT8,RGL1,STX1A,SYT1,COBL,TACR1,ANKRD12,MTCL1,FAM208A,IQCE,TBL1X,DMXL2,SATB2,CUX2,TCF12,NAT16,USP32P1,CRTC1,DICER1-AS1,AP4E1,ARL10,TIAM1,TMPO,BEX4,PRRT1,CSMD1,TP53BP2,TRIO,RUNDC3B,TRPS1,CA14,CLHC1,FLRT2,BCL2L13,MTCH1,VLDLR,GUSBP1,ZNF24,SPIRE1,ZFAND5,FAM47E,HRASLS,SMIM8,FBXO36,ADAMTSL3,TRAM2-AS1,NETO1,ZNF30" MicroRNA hsa-miR-29a:mirSVR_lowEffct hsa-miR-29a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-90 7.87E-87 1.56E-89 1.43E-88 257 1612 "VWA5B2,ABCF1,ACADM,CLK4,SYS1,NDRG2,FMNL2,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,SEMA6A,CARNS1,AMPD3,ZFAT,CDC42BPA,LRCH2,FGD2,CCDC146,KCNAB2,UPRT,PHYHD1,TNRC6C,USP37,SHROOM2,CDK10,ARHGDIG,MARK4,ZBTB10,DOCK11,ADAM15,SYNJ2,MTMR2,JAZF1,LDLRAD4,CA4,CACNA1A,KALRN,CAMK2G,RUNX1T1,ARHGEF25,C1orf52,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,B4GALT6,CNOT8,EPS15L1,CLTC,QKI,SULT4A1,WHRN,AKAP5,NCOR2,ARHGEF10,CSNK1E,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,DCAF4,CYBB,HDAC9,ARHGAP32,KATNAL2,RIPOR2,HDAC4,IP6K1,BRINP1,ARMCX4,ELMSAN1,DDX46,ALKBH8,PLPPR4,CDON,DPYSL2,ARRDC4,ECM2,WDPCP,SEMA3D,GOLGA7,KCTD3,PLEKHA1,C8orf37,MTSS1L,ENPP6,ERCC2,NCALD,SPEG,MRPL37,TLR7,CLVS1,POLR1B,FGFR1,HPCAL4,IP6K2,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,SMC2,TRIM16,STAU2,MSANTD4,ABLIM2,ERAP1,TUBGCP4,SRCAP,PCDH17,PPARGC1A,DBF4,GLI2,STARD3,POLL,WDFY3-AS2,GP1BB,GRIA2,C1QL4,ADAMTS13,RNF165,MUM1,RASSF8,TNFAIP8L3,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,DISP2,TTYH2,LAMP2,STMN1,LIFR,MAT2A,AQP11,SCAMP5,MKLN1,COL28A1,COMMD5,MYO9A,RTL5,NEFM,NFE2L2,NFIX,OXTR,P2RY1,PALM,PAX6,CDK18,PIK3R1,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,RETREG2,WBP1L,PIGG,EML5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RDX,TRIM68,RET,ERI2,GTDC1,ZFHX4,SETD5,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,EMID1,ABCA11P,SMPD3,GALNT10,FOXRED1,KIF21A,PPM1E,PKNOX2,SLC6A8,SEPHS1,LGI3,TTC17,MAPKBP1,MBD5,SNRPN,DOP1A,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,ZNF302,ERBIN,CEP68,ADHFE1,STX1A,NSFL1C,ZC3H4,SUPT5H,SYNE2,ADAMTS17,SYN2,COBL,C12orf76,TACC1,SIN3B,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZNF346,SYNPO2,ELP5,AMACR,TUBB1,CLEC2L,UBTF,PLEKHH2,ZNF24,ZBTB38,ZFAND5,CADM2,TRIM16L,PARP11,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-377*:mirSVR_lowEffct hsa-miR-377*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-90 1.20E-86 2.36E-89 2.17E-88 257 1615 "KCNH8,ACHE,ADCY6,TMCC3,WDR35,TXNDC16,AK2,SRPX,ABCD2,ZNF687,PPFIA3,LGR5,SFMBT2,SEMA4G,LINC00173,CDK13,MARCH3,CHID1,EIF4G3,ATP2A2,DPY19L3,ADGRB3,BBS2,NRP2,CFLAR,FUBP1,SGCE,RAB29,CA12,CACNA1B,CACNB4,PRC1,LRRFIP1,LARGE1,NRXN3,STOML1,SRP14-AS1,ARHGEF6,SUMF2,LETMD1,COL9A3,ZFP28,ZNF385A,FAM171B,SNCAIP,OSBPL3,VAC14-AS1,DZIP3,PHF14,RIMS2,RIPOR2,ZNF337,TM9SF4,IST1,DGKG,B3GAT3,PLPPR4,SPOCK3,RAB39B,HS3ST2,DOCK2,DPYSL2,RCAN1,DNAJB6,ABCC5,GOLT1B,SNX29,WDPCP,PHF20L1,APH1A,EBI3,KMT5B,RASA4,TMEM35A,CALCRL,USPL1,EIF1,ENO2,EPB41L2,EPHB1,SIRPB1,ABCA8,ACSL4,CORO2B,CHST15,FGF14,BAIAP2,MEX3B,SEMA4D,FLT1,EFCAB2,PDLIM5,ERGIC3,KHDRBS3,CELF1,STAU2,MSANTD4,DOT1L,MEGF10,GABRG2,FAM120B,ZNF559,DISC1,LRRC37A6P,GGT7,GLYR1,MSL3,ZNF638,LUZP2,KCNMB4,WDFY3-AS2,ADGRA3,PCLO,GRIA2,ADAMTS13,SERP2,ZNF496,LINC01089,ZBTB49,HAS2,TOX2,PADI2,ELOVL5,GABARAPL2,SYNPO,USP51,TCEAL6,HSF2,SCIN,FAM69A,ITGA7,SLC35G1,IPO5,STMN1,PAXBP1,NCOA7,LSS,MAN2A2,MAP2,MAP6,MBD1,MBNL1,MBP,SRSF12,AFDN,XRRA1,MMP16,ADAM22,MYO7A,SFR1,NEFM,NEK1,NF1,ALDH1L2,DNHD1,NUCB2,ZNF713,PCDH8,PDE1C,PDE4D,SMIM7,PRIMPOL,TRHDE,MINDY2,PPM1B,NKAIN4,CEP41,PRKCB,EPDR1,WBP1L,ANKHD1,TMEM260,PTPRN,ZNF615,PPP2R3C,PID1,CEP97,REV3L,PRRT2,RNH1,ALG9,YY1AP1,EPHA10,FBXW7,BAALC,ZNF671,RPS20,MEG3,ZNF568,RYR3,RMI1,S100B,SALL1,ATXN7,SUPT20H,COPZ1,HSPA4L,ARX,ABLIM3,SLC11A1,KBTBD4,SLC14A1,CPEB4,IFT122,ANKFN1,SNRPN,TMCC1,PDZD2,TRERF1,BDP1,SP2,GLT8D1,SPTAN1,LHPP,SSPO,NEK4,RGL1,SYNE2,TMEM150C,COBL,ANKRD28,C12orf76,MTCL1,CAMTA1,DNMBP,ADGRL3,TBCEL,FBXW11,KLHL4,DMXL2,SATB2,TRIM2,PUM2,ITGB3BP,AP4E1,ZNF34,PRRT1,TPM1,C9orf85,TSN,SSBP2,WIPF1,CLDND1,ZIC2,TRIM9,LYPD6,TCEAL7,SMARCAD1,EMSY,HPS4,CIAPIN1,NAV3,KCNAB1,DNAH10,FZD3,TMEM63C,JMJD1C" MicroRNA hsa-miR-146b-5p:mirSVR_lowEffct hsa-miR-146b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.02E-90 1.69E-86 3.33E-89 3.07E-88 276 1855 "ACADM,EMILIN3,XKR4,FMNL2,CCDC85A,ADD1,RNF150,MTA3,AP2A2,ZNF608,CASKIN1,OSBPL1A,OSBPL8,ZNF578,ABCD2,GPRASP2,SYT13,AMPD3,ANK2,CCDC146,USP37,PPP4R4,DNAH17,ADAM23,ADAM15,LINC00847,BCHE,RGS9,BLM,DST,SYNJ1,CACNB4,CALB1,SLC25A14,PRC1,CD86,DCLK1,DLGAP1,UBE2L6,CNTN1,AKAP7,FAM149A,AKAP5,RCHY1,ZFP28,SEC31B,CREM,RBM39,RNF14,ANKRD44,CRYM,CS,OSBPL3,GALNT9,PNPLA8,GREB1,ARHGEF4,ZSCAN23,ARHGAP32,GAPVD1,SNPH,RASSF2,IST1,DNAL1,HEPH,FBXL5,KIAA0319,LYPD1,SGSM2,DLX1,GRIN3A,DOCK2,HEYL,EBI3,MBNL2,EGR3,TMEM132E,AASS,TENM1,CALCRL,RABEPK,NCALD,MRPL10,TLR7,KATNAL1,ADGRV1,MRVI1,FAM198B,DLC1,ST3GAL6,CHST15,ZNF589,FECH,FER,GTF2IRD2,OLFM1,PCYOX1,SYNCRIP,IQCG,FLT1,SMC2,ATP6V1H,ATP2C1,ZNF605,STAU2,GABRG1,GAD1,IP6K3,ERAP1,SIGLEC8,ZNF559,ACSS1,KIAA1841,SULT1C4,SESN1,GGTA1P,TOX3,MSL3,DCLK2,FERMT2,LILRB4,SPACA9,PRDM5,BVES,RABL2A,ADAMTS6,MUM1,PADI2,ZHX1,VSIG4,AGBL5,CELF5,MSL1,GAREM2,SCIN,IL6R,ZNF678,CREG2,LAMA2,SYTL4,NCOA7,ZFYVE27,MAP4,MAP6,LYPLAL1,MAT2A,CHIC1,TM6SF1,MEIS1,PPM1L,AFDN,MXI1,LAYN,MYO5A,MYO7A,ZNF862,SFR1,NF1,NPR2,NTRK2,NTRK3,OPA1,PCDH9,XRN1,KCTD15,NLE1,PLCL1,TRHDE,MAGEL2,PPM1B,PPP2R5E,PRKACB,MAPK4,GRAMD1C,PIGG,CNTLN,PTCH1,ZSCAN32,TMEM255A,SH3TC2,NWD1,RASGRF2,RFX2,RNASEL,C12orf49,ELP2,NEK11,ZC3H14,GLDN,SALL1,SATB1,LRFN5,PRCD,SCP2,GALNT10,FOXRED1,MRAS,TRA2B,COPZ1,CHD9,FHOD3,PPP4R3A,DHX30,ARHGEF40,SLC9A5,SLC11A1,ZFP1,RCOR3,INAVA,LIMCH1,MBD5,SNRPN,TMCC1,DOP1A,TRERF1,FNBP1,DOK5,ZSWIM8,SPART,ATP10B,ITPRID2,NECAB1,ZC3H4,SYN2,SLC37A2,TACR1,DNMBP,PDLIM2,MGRN1,ATMIN,SIN3B,USP32P1,FRYL,CCDC173,SIK3,VWCE,PMS2CL,DICER1,SIRT1,ZFPM2,ITGB3BP,GALNT17,TIAM1,MTMR14,TIMP4,BHLHB9,TLR4,PRRT1,CSMD1,ZNF346,SYNPO2,TTTY15,CLHC1,MTCH1,WIPF1,WRN,XPO1,ZFAND5,SMARCAD1,EMSY,DNALI1,SLC38A1,LINC02210,ADAMTS9,HPS4,FAM47E,PCBP4,MPPE1,WNK3,FZD3,UBE3B,KAT6A,FRMD6,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-297:mirSVR_highEffct hsa-miR-297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.06E-90 1.71E-86 3.36E-89 3.10E-88 232 1322 "CLK4,KLHL32,KIAA1211,KLHL13,OSBPL8,CC2D2A,C1QTNF3,ALCAM,ABCD2,CDC42BPA,MAP4K3,NCOA1,INSYN2B,SLC4A4,EIF4G3,ATP6V0A1,ADAM23,BMPR1B,SYNJ1,ARHGEF7,WASF1,CALB1,KALRN,KRIT1,LRBA,KCNAB3,TIGD7,CCPG1,RAB33A,NRXN3,C4orf33,HECTD1,AKAP7,ARMC8,COL9A3,SLC4A8,CNRIP1,CLOCK,ABCG1,CSF1R,CSF2RA,OSBPL3,PDE4DIP,ERC2,MYADM,ARHGAP24,EARS2,DGKB,TMEM170A,MYEF2,SNAP91,SGSM2,GRIN3A,DRP2,PDCD6IP,SNX29,RASGRP1,EGFR,MBNL2,COPS4,PLEKHA1,C8orf37,CALCRL,SRRM1,VPS26C,EXTL2,F8,SH3YL1,ACSL4,FCGR3A,SLC9B2,FGFR1,SUCO,SYNCRIP,FLT1,PSD2,SLC37A3,TPK1,ATP6V1H,ZNF605,CELF1,STAU2,MEGF10,GABRB3,GABRG2,C15orf41,DISC1,GATM,MSTN,SESN1,ADAM28,PPARGC1A,TCERG1,CBX1,KIAA1958,PLPP7,BTN2A1,BVES,HAS2,ZDHHC15,SMAP1,IFI16,ZNF546,INSM1,KCND2,KIF2A,IPO5,STXBP5,NCOA7,PIK3AP1,MARK1,AQP11,MATN2,MATN3,LRP1B,MEIS1,MID1,MSR1,MX1,MYO9A,P2RY13,NF1,NFE2L2,NRCAM,NTRK3,OPA1,CLDN11,ETFRF1,OLA1,NALCN,PIK3C2A,PIK3R1,ZNF655,XRN1,STRN3,LRP12,PSAT1,EXOSC10,NKAIN4,GDPD1,SAMD9,QRICH1,ANKHD1,BDNF-AS,PTPRE,PTPRG,ACSM5,ERI2,MORC4,FIGN,RIC8B,PBRM1,RNASEL,CCDC82,DCUN1D2,ROBO1,ROBO2,CCDC102B,RPE,MCMBP,GLDN,MEG3,CLIP1,ZNF354C,TRAPPC13,FAM192A,SEMA6D,SCN8A,SCP2,ZFP2,HSPA4L,SGK1,FERMT1,FNDC3A,FHOD3,R3HDM2,SLC6A8,CCDC88A,ELMO2,BTBD7,ATF7IP,ZNF667,RCOR3,SNAP25,MYO16,BDP1,SOX15,TEX2,PEG10,MCF2L2,CAMTA2,SSTR2,NKAIN2,NEK4,ADHFE1,KLHL7,PRRC2C,ADGRL3,TCEA1,TCF4,DMXL2,TCF12,SYNE1,PUM2,AP4E1,SLC44A1,ARL10,TMPO,CSMD1,TPM1,RUNDC3B,SSBP2,FLRT2,PLEKHH2,ZNF709,VLDLR,XRCC4,PCDH20,MICU3,ZNF28,ZBTB38,FSTL5,ANKS1B,EMSY,CADM2,RNF103,ADAMTS9,KCNAB1,FIP1L1,KLHDC1,FRMD6,RNF146" MicroRNA hsa-miR-302b:mirSVR_highEffct hsa-miR-302b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.12E-90 1.75E-86 3.43E-89 3.15E-88 248 1509 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,ATP6V1G2,BACH1,MPDZ,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,ZNF501,SEPT7,LRRFIP1,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,ABCG2,C4orf33,AKAP5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,ANKRD44,SNCAIP,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,HDAC9,KIAA0586,DGKG,YTHDC1,ZNF804A,MYEF2,ZC3H11A,GRIN3A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,E2F6,WDPCP,EDNRB,ANKRD46,HIPK3,SEMA3D,EGFR,KMT5B,GOLGA7,IRAK4,TENM1,PLEKHA1,C3orf18,DCTN4,STX2,VPS26C,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,MEGF11,IGSF5,TUBGCP4,MSTN,ADAM28,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPR12,GPR34,PCLO,UBE2QL1,ZDHHC15,SMAP1,MSL1,IDH3B,KCNN2,CYP27C1,LAMP2,LIG4,SYTL4,HECTD2,NCOA7,LSS,ZNF667-AS1,MARK1,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,OPA1,GPR137C,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,EPB41L4B,DRAM2,RASGEF1B,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,CNTLN,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,RET,GTDC1,FIGN,RFX3,RIC8B,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,MCMBP,RPS20,RTN1,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,ADGRL3,TBCEL,TCEA1,CUX2,ZEB1,SZT2,PCDHB3,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NACC2,NR2E1,TNS1,RGMB,PPIL6,ZNF709,VLDLR,PCDH20,TRIM9,LYPD6,LAMP5,CADM2,PRTFDC1,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-23b-3p:TargetScan hsa-miR-23b-3p TargetScan 4.15E-90 2.32E-86 4.53E-89 4.17E-88 195 926 "CLK4,C3orf14,PWWP2A,RNF150,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,N4BP2L1,ADAM23,NRP2,KSR1,JAZF1,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,MAGI1,DLGAP2,DLGAP1,CFL2,NRXN3,CLCN3,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,GPSM1,PYGO1,GAPVD1,MAML1,DAPK1,PITPNC1,KIAA0753,FAM107B,DLX1,RAB39B,CPEB2,DTNA,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,FGF14,ANKFY1,CELF1,FUT9,CHL1,GABRB3,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,PCLO,HAS2,FRMD5,BACH2,HNF4G,NEGR1,IL6R,KCNB1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,ALDH1L2,NFIX,NOVA2,OXTR,PDE3A,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,PTGR2,AP1AR,SAFB,SATB1,ATXN7,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,DZIP1,EPN2,BTBD7,CPEB4,EPC1,MBD5,FAM126B,POGZ,NUDT10,MMS19,PJA1,KIAA1107,ATMIN,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,NACC2,CBX5,ASXL3,DOK6,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-23c:TargetScan hsa-miR-23c TargetScan 4.15E-90 2.32E-86 4.53E-89 4.17E-88 195 926 "CLK4,C3orf14,PWWP2A,RNF150,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,N4BP2L1,ADAM23,NRP2,KSR1,JAZF1,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,MAGI1,DLGAP2,DLGAP1,CFL2,NRXN3,CLCN3,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,GPSM1,PYGO1,GAPVD1,MAML1,DAPK1,PITPNC1,KIAA0753,FAM107B,DLX1,RAB39B,CPEB2,DTNA,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,FGF14,ANKFY1,CELF1,FUT9,CHL1,GABRB3,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,PCLO,HAS2,FRMD5,BACH2,HNF4G,NEGR1,IL6R,KCNB1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,ALDH1L2,NFIX,NOVA2,OXTR,PDE3A,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,PTGR2,AP1AR,SAFB,SATB1,ATXN7,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,DZIP1,EPN2,BTBD7,CPEB4,EPC1,MBD5,FAM126B,POGZ,NUDT10,MMS19,PJA1,KIAA1107,ATMIN,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,NACC2,CBX5,ASXL3,DOK6,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-23a-3p:TargetScan hsa-miR-23a-3p TargetScan 4.15E-90 2.32E-86 4.53E-89 4.17E-88 195 926 "CLK4,C3orf14,PWWP2A,RNF150,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,N4BP2L1,ADAM23,NRP2,KSR1,JAZF1,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,MAGI1,DLGAP2,DLGAP1,CFL2,NRXN3,CLCN3,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,GPSM1,PYGO1,GAPVD1,MAML1,DAPK1,PITPNC1,KIAA0753,FAM107B,DLX1,RAB39B,CPEB2,DTNA,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,FGF14,ANKFY1,CELF1,FUT9,CHL1,GABRB3,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,PCLO,HAS2,FRMD5,BACH2,HNF4G,NEGR1,IL6R,KCNB1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,ALDH1L2,NFIX,NOVA2,OXTR,PDE3A,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,PTGR2,AP1AR,SAFB,SATB1,ATXN7,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,DZIP1,EPN2,BTBD7,CPEB4,EPC1,MBD5,FAM126B,POGZ,NUDT10,MMS19,PJA1,KIAA1107,ATMIN,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,NACC2,CBX5,ASXL3,DOK6,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-320c:mirSVR_highEffct hsa-miR-320c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.78E-90 2.68E-86 5.21E-89 4.79E-88 238 1394 "ABCF1,KCNH8,SYN3,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK13,ZBTB10,TMEM108,DPY19L3,CFLAR,KSR1,CA8,PTBP2,SLC25A14,VXN,SPAG9,CBLN1,CBR1,LDB2,CCNH,MTMR7,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,ARHGEF6,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CNRIP1,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CCDC144A,HDAC9,GPRASP1,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,CDKL3,ADGRV1,EYA1,NRN1,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,ANKFY1,COQ5,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,ZMAT1,B4GALNT1,SYT17,C15orf41,DISC1,ARFIP1,DBF4,GLYR1,MAP7D2,LOXL3,BVES,HAS2,ARHGAP36,VSIG4,GABARAPL2,AGBL5,NEGR1,SMAP1,MSL1,SOWAHA,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,ADAM22,MXI1,NELL2,NF1,CNOT4,PCDH9,PDE3A,CYTL1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,MAPK9,GRAMD1C,APTX,CNTLN,PTPRG,TMEM255A,SH3TC2,RBBP6,ZDHHC14,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,RPL15,ZC3H14,ZNF671,ADAL,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SUPT20H,HSPA4L,FERMT1,HKDC1,FBXO11,FNDC3A,CNKSR2,WDR47,SLC6A8,CPEB4,CDK5RAP2,LIMCH1,CMTR2,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,KAT6B,TPM1,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,UBE3A,VLDLR,GUSBP1,XPO1,XRCC4,ANKS1B,EMSY,PRTFDC1,PRDM10,PPP1R3F,ST7,HNRNPA3,PHTF2,NLRP3" MicroRNA hsa-miR-3162:mirSVR_lowEffct hsa-miR-3162:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.82E-90 2.70E-86 5.24E-89 4.83E-88 251 1548 "KCNH8,ACADM,ASIC1,NCKAP5,GALNT16,GALNT13,ADD2,ADORA2A,KIAA1211,RNF150,PTCHD1,CASKIN1,TBC1D14,ADGRF5,MARCH4,FAM135A,LRFN1,CDC42BPA,LRCH2,LCORL,PHF12,APLP1,PHYHD1,BCAS1,SHROOM2,SEMA4G,PRX,SLC4A4,ZNF583,SLC2A11,RNF182,ADAM23,MPDZ,DNAJC27-AS1,CFLAR,SCAPER,CFAP410,CALB1,ISPD,RUNX1T1,USP2,SEPT7,KCNAB3,CACNA2D2,ASIC3,PLEKHB1,LHX2,EPS15L1,CNN3,ZNF385A,CREM,CRYBB1,GDA,CSF1,CSF1R,OSBPL3,VCAN,SOCS5,PDE4DIP,FAM169A,PLCXD3,CYBB,BOC,ZFYVE16,TM9SF4,DGKG,ARMCX4,PITPNC1,ZNF804A,ELMO1,KLHL3,SNAP91,CHRDL1,CDON,DPP6,ACOT8,DNAJB6,FARSB,E2F5,EDNRB,SUGP2,APH1A,IRAK4,CERCAM,ELN,EPB41,COQ7,VPS26C,SIRPB1,CD320,F5,CLVS1,ABCA8,PTK2B,DLC1,CHST15,FDFT1,ZNF589,FGF11,BAIAP2,POLK,FLT1,AK8,STAMBP,NEURL4,ZMAT1,GAA,GALNT15,GABRB3,GABRG2,INPP5K,GCK,MSL3,GNG4,STON1,DIDO1,PRDM5,RNF165,BVES,RNFT2,GUCY1B1,IRAK3,TOX2,ZHX1,SYNPO,ZNF491,SMAP1,ZNF181,ZNF678,SLC35G1,KCNB1,KCNJ5,TTYH2,LAMP2,ZFYVE27,MARK3,MBP,ADAM11,KCTD6,SCAMP5,ZNF680,MYO9A,NELL2,ALDH1L2,NINJ2,NUCB2,OCRL,PDCD2,PDPK1,GNG2,ZDHHC8,PIK3C2A,FAM216A,SLC25A23,PURG,SH3KBP1,PPP2R2B,PPP3CC,PRKACB,MAPK4,HYDIN,RELN,BDNF-AS,TMEM260,ZSCAN32,PTPRE,CASTOR1,TUG1,QDPR,CEP97,ZNF493,ZDHHC14,GAL3ST4,ERI2,CARF,KIRREL1,NEK11,SPIN3,STK32B,LRRK2,ST6GALNAC6,KCNIP1,ZNF568,RYR3,AP1AR,SARS,ATXN7,SCN8A,PEAR1,SEC14L1,CASC3,FAM102A,KIF16B,FBXO11,FAM214B,ARHGEF40,CCDC88A,SNRPN,ZSWIM8,SP4,NMNAT2,TSPYL2,NFASC,ITPRID2,ZSCAN29,SEPT3,NECAB1,RHBDL3,ARHGEF9,FAM208A,TBCEL,IQCE,ZFP90,RPGRIP1L,USP22,CLASP1,SYNE1,PHF24,SLC19A3,TEK,SIRT1,RIMBP2,R3HDM1,RASD2,NPL,WBP2,ZNF346,SYNPO2,SSBP2,TTTY15,HIRA,FAM155A,LMF1,WIPF1,GUSBP1,EML6,SH3GLB2,MEIS3,EVI5,STOX2,RNF103,GAL3ST3,PCBP4,PDSS2,RGS7BP,GJC2,CASC15,RNF170,NETO1,RNF146,FAM198A" MicroRNA hsa-miR-1910:mirSVR_lowEffct hsa-miR-1910:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.12E-90 3.42E-86 6.63E-89 6.11E-88 274 1835 "DGCR6,CLK4,KDM5D,XKR4,GALNT16,ADCY6,TMCC3,GALNT13,RNF150,FAHD2CP,MTUS1,HECW2,RTL9,OSBPL8,CC2D2A,CARNS1,ZNF687,OGT,FGD2,PI16,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,NT5C3B,USP37,AQP6,CDC14B,CDK10,SFMBT2,TMEFF1,SPTBN4,ADAM15,ADGRB2,NAE1,HAP1,CAMK2G,VXN,CH25H,RUNX1T1,ZNF501,P2RX6,ENTPD6,C1orf52,AP4M1,SEPT7,ZBED1,ZMYM4,CDO1,DIS3L,MYL6B,NGEF,QKI,IGLON5,ARHGEF6,CNTN1,WHRN,COL4A5,SLC4A8,COX4I1,SMARCAL1,MYRIP,ZFP28,SLC35F1,FAM171B,CRMP1,ANKRD44,TRIM69,RGS6,VAC14-AS1,FAM169A,UBXN2A,ARHGEF4,HDAC9,RIPOR2,ZNF337,DGKG,SPOCK2,AIF1L,GIT2,ARMCX4,SPATA2,YTHDC1,MFAP3L,KIAA0319,ZC3H11A,POM121,EXOG,DMD,DNAH9,CD99L2,DPP6,DRP2,DTNA,TOM1,FARSB,DNM1L,E2F5,SEZ6L2,EDNRA,EDNRB,FEM1B,KLHL5,FRY,APH1A,MBNL2,AASS,KCTD3,IRAK4,HSPA12B,F5,REEP2,TBC1D16,PTK2B,KAT8,PPP1R1B,FER,FHL1,POLK,IP6K2,FLT1,SLC37A3,C2orf88,ATP2C1,ERGIC3,CELF1,ABLIM2,GABRG2,ZNF274,TMEM8B,LRRC37A6P,GCNT2,SESN1,ADAM28,GGTA1P,LYVE1,GLI2,TOX3,TNRC6A,STARD3,DCLK2,CCDC184,PCLO,GRB10,PLCD4,GSTM5,KAT7,PSIP1,SLC2A6,HAS2,FRMD3,TNFAIP8L3,ZDHHC15,TJAP1,A1BG-AS1,STXBP5,PAXBP1,PIK3AP1,MAN2A2,ZFYVE27,MAPT,MBP,TM6SF1,MEF2C,KITLG,POC1B,MKLN1,GIT1,BLOC1S2,PTOV1,NINJ2,NOVA1,SLC11A2,NTRK3,IGSF11,PAX6,PCSK5,PDE1B,GPR173,PFKFB2,PFKFB4,ZDHHC8,PLCB2,MTRF1L,PMP22,MAPKAP1,SCHIP1,ING3,MBOAT7,PPP2R5E,PPP3CA,RASGEF1B,GRAMD1C,RELN,BCAS3,CNTLN,ELOVL2,PTPRE,C1orf109,PEX2,RAD17,SH3TC2,NWD1,RAP1GDS1,ENOX1,RET,ZDHHC4,UBR7,RGS3,RGS12,ALG9,ARMC5,NEK11,EPHA10,STK32B,PTGR2,ZNF331,HES6,TNFRSF19,ZNF821,ARX,KIF16B,DZIP1,BTBD3,KANSL3,ATF7IP,OGDHL,CDK5RAP2,SMARCD3,MBD5,TMCC1,NMNAT2,KDM4C,TEX2,PEG10,IQSEC2,CDK19,RBM26,STAU1,VPS13A,TACR1,EXOC7,PDLIM2,DMXL2,USP32P1,FRYL,CYB561A3,PMS2CL,AKTIP,ARL10,CHST5,ELP5,DCBLD1,TTTY15,UBTF,GORASP1,OSBP2,CCDC14,PCDH20,ZFP37,ZNF45,ZBTB38,ANKS1B,UPF3A,EMSY,STOX2,SIGLEC10,EPM2A,DOCK8,RTN4,CASC15,JMJD1C,IFT88,NETO1,FAM181A" MicroRNA hsa-miR-92b:mirSVR_lowEffct hsa-miR-92b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.50E-90 3.63E-86 7.03E-89 6.47E-88 257 1623 "VWA5B2,AS3MT,ELFN2,CCDC85A,PWWP2A,BEND6,MTA3,HACE1,OSBPL8,PCDH10,UNC79,AMPH,LRCH2,LCORL,PKP4,APBB2,MAGEE2,DDO,PPP4R4,CASK,RGS20,CDK13,ZBTB10,NCOA1,SLC4A4,ATP1B3,DOCK11,BACH1,RGS9,FUBP1,SLC16A4,L3MBTL4,DLGAP2,CLGN,PLAA,NGEF,LY86,AKAP7,PCYT1B,ARMC8,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,DGKB,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,WDR20,NR1D2,MAMLD1,ABCC5,EDIL3,FAM13A,PHF20L1,EIF4G2,TENM1,STARD3NL,EIF1,EMX2,ERBB4,MRPL37,DNAJC27,CLVS1,SCML2,DLC1,RACK1,ST3GAL6,FKTN,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF10,GABBR1,MTHFD2,LRRC37A6P,KIAA1841,GATM,DBF4,ZNF638,PRRC2B,FUT10,GRM8,GSTT2,SOX21,GUCY1B1,ZHX1,HMGCR,LRRC75A,EID2B,INSM1,JAK2,METTL21A,KCND2,IPO5,PAXBP1,HECTD2,NCOA7,PACRG,MAP4,MARK3,TM6SF1,MEIS1,AFF1,MMP16,MYH3,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PFKFB4,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,PPARA,PPM1B,PPP2R5E,NKAIN4,RANBP3L,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,PTPRG,STRC,MARCH1,SLC25A48,USP47,RAD51D,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,SLC25A36,ZFHX4,STK32B,LRRK2,RPS20,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,ATXN7,RASA3,SGK1,FERMT1,SHC4,CHD9,FBXO11,SYBU,FAM81A,SEPHS1,ATF7IP,SMARCC2,IFT122,LMBRD1,SNRPN,SOX11,DOK5,HECW1,TSPYL2,MCF2L2,RBM26,ZC4H2,SS18,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,KLHL4,ATMIN,DMXL2,ZEB1,SYNE1,NAT16,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,CSMD1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,PLEKHH2,XRCC4,ZNF28,ELFN1,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,SENP7" MicroRNA hsa-miR-422a:mirSVR_lowEffct hsa-miR-422a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.99E-90 3.91E-86 7.55E-89 6.95E-88 264 1710 "CLK4,SYS1,KDM5D,ADCY6,CCDC85A,TMCC3,ADD1,ADD2,ADORA1,ADORA2A,RNF150,PTCHD1,MTA3,AP2A2,PCDH19,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,APBA2,KCNAB2,VAT1L,PPFIA3,SPTBN4,ARNTL,MARK4,NUMB,DNAJC27-AS1,KSR1,ARHGEF7,GYG2,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,VXN,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,SOCS6,ABCG2,CNGA3,FHL5,FAM149A,COL4A5,ABI3BP,CLOCK,HAPLN1,CRYM,VAC14-AS1,UBXN2A,ZSCAN23,ARHGAP32,INTS1,SPATA2,ZBTB24,TMEM130,SV2B,WDR20,DLX1,RAB39B,USP3,DMTF1,PDCD6IP,EDN1,RASGRP1,SUGP2,MBNL2,IRAK4,PLEKHA1,MRNIP,TMEM35A,VPS13B,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,ZSCAN30,STRADA,SEC24B,MED12L,SUCO,PCYOX1,AGAP3,PSD2,ZBED3,APOPT1,HRASLS5,ZNF44,GALC,B4GALNT1,RAPGEF6,ZNF274,IP6K3,SIGLEC8,INPP5K,ADAM28,GGTA1P,DHRS4,BRD8,TXNL4A,ZNF638,DCLK2,CLASRP,ZBTB49,BVES,IRAK3,SYNPO,LRRC75A,CELF5,IDH3A,GAREM2,KNDC1,TJAP1,IL6R,TMEM240,KCND1,KCNN3,L1CAM,HECTD2,MAT2A,AQP11,AFF1,MSR1,PTOV1,MYO7A,RTL5,HNRNPM,NCF2,VWA2,NOVA1,NTRK3,NUCB2,SETD4,PCDH9,PDCD2,PDE1B,GPR173,TMOD2,PFKFB4,TMIE,ZNF655,CCSER2,XRN1,PLCB2,SH3KBP1,PPM1B,PPP3CA,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,CNNM2,CYBC1,PEX2,NWD1,RAP1GDS1,RASGRF1,ERI2,RGS3,PRIMA1,KCTD17,CARF,GSTCD,PCMTD2,SNX22,NEK11,RPL15,ARMH4,SPIN3,GLDN,TCP11L1,AP1AR,MAPK12,PEAR1,CASC3,ZNF821,GALNT10,SH3BP2,ANKRD6,EPN2,PKNOX2,ARHGEF40,BTBD7,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,SOX3,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SSTR1,LARP4,ZSCAN29,SEPT8,ADHFE1,STX1A,ARHGEF9,SYN2,ANKRD28,MMS19,MLST8,MCF2L,FBXW11,ATMIN,WSCD1,SIN3B,TCF12,NAT16,PCDHB7,TEK,FAM200B,ZNF34,SLC44A1,ARL10,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,AMACR,DCBLD1,RUSC1,CLHC1,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,KCNT2,SH3GLB2,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,FAM198A,JPH3" MicroRNA hsa-miR-1913:mirSVR_lowEffct hsa-miR-1913:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.01E-90 3.92E-86 7.56E-89 6.96E-88 266 1735 "ABCF1,ABR,ASIC1,NDRG2,ADCY6,FZD9,ADORA1,ADRA1B,OSBPL1A,C1QTNF1,ADGRF5,SEMA6A,CARNS1,FAM135A,AMT,FGD2,MYH7B,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,MADD,ARNTL,CDK13,CHID1,ZNF583,SLC2A11,RNF182,TTLL9,RGS11,CFLAR,CACNA1I,KALRN,ARHGEF25,LDB2,USP6,CD86,CDC25B,COPB2,CBARP,CHGB,ASIC3,PLEKHB1,FBXO7,IGLON5,ARHGEF6,SMARCAL1,SEC31B,SH2B1,SNCAIP,SLITRK5,APPL1,GPSM1,RUBCN,KATNAL2,ZFYVE16,EARS2,ZNF337,ARMCX4,TIAM2,MFAP3L,C2CD2L,POM121,CHRDL1,DMD,DPYSL2,TOM1,DNM1L,AASDH,EDN1,EDNRB,PHC2,CNNM1,KLHL5,CELSR3,FAM13A,TMEM132E,ING4,TNK2,C3orf18,CALCRL,RASGRP2,SRRM1,SPEG,MRPL37,MRVI1,CLVS1,TMEM132C,PTK2B,DLC1,FGF11,SPSB4,BAIAP2,FOXF2,AGAP3,PSD2,POMT1,ATP6V1H,ZNF605,KHDRBS3,CELF1,DLL3,HHIPL1,AP4B1,FYB1,GAA,B4GALNT1,ZNF234,GHDC,DISC1,SEPT9,CPLX2,ALDH1L1,TUBA8,GFER,USP19,BRD8,GPD1,CCDC184,TMEM121B,DIDO1,C1QL4,ADAMTS13,GRIK5,GRIN2C,GSN,CLASRP,KAT7,NCKAP1L,ICA1,IRF8,MSL1,MYLK2,KNDC1,IL6R,TMEM240,INPP5B,ITGA7,CDH20,KCND1,KCNH2,STXBP5,SFXN5,MAP6,MATN2,MEIS1,MEIS2,MGAT3,SCAMP5,AFDN,XRRA1,GIT1,NELL2,NF1,CNOT4,NTRK3,PDE4A,PDE4B,OLA1,SNX10,XRN1,TMEM38A,PLCB2,STRN3,ING3,RETREG2,POU6F1,TATDN3,KANSL1,HYDIN,WBP1L,TMEM104,PTN,PTPRB,CASTOR1,PTPRG,NKAIN1,USP47,RASGRF1,GAL3ST4,TRIM68,RGS3,KIF7,PBRM1,LGI2,EXD2,KIRREL1,CCDC102B,SNX22,EPHA10,KIAA0895L,ATP8B4,SGSM1,STK32B,PTGR2,MEG3,ABCA11P,ATAT1,SATB1,SBF1,SCP2,HES6,SEC14L1,GALNT10,FERMT1,SHC4,CHD9,NLGN1,PEX26,SLC6A8,SLC6A11,SLC11A1,SLC12A4,CDK5RAP2,INTS9,MAPKBP1,SNRPN,USP33,FAM219A,TRERF1,BDP1,TSNAXIP1,ZSWIM8,NMNAT2,KDM4C,ERC1,SPTB,NFASC,ATP10B,SUPT5H,NUDT10,DNAJC9,TMEM150C,CAMTA1,EXOC7,NEU4,CUX2,SYNE1,NAT16,TNS2,FRYL,HIF3A,RNF216P1,PMS2CL,LRRC8A,BEX4,TPM1,NPL,ZNF346,PPIL6,ZKSCAN5,RPL7L1,UBTF,PLEKHH2,LMF1,KLC2,RICTOR,LGI4,ELFN1,ATP6V0E2,MAP3K12,SEMA3B,SLC17A7,PPP1R3F,PCBP4,ADAMTSL3,FAM181A" MicroRNA hsa-miR-320a:mirSVR_highEffct hsa-miR-320a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.34E-90 4.66E-86 8.95E-89 8.24E-88 240 1421 "ABCF1,KCNH8,SYN3,NCKAP5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,SPOP,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK13,ZBTB10,TMEM108,DPY19L3,CFLAR,KSR1,ARHGEF7,CA8,PTBP2,SLC25A14,VXN,SPAG9,CBLN1,CBR1,LDB2,CCNH,MTMR7,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CCDC144A,HDAC9,GPRASP1,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,CDKL3,ADGRV1,EYA1,NRN1,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,ANKFY1,COQ5,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,ZMAT1,B4GALNT1,SYT17,C15orf41,DISC1,ARFIP1,BRD8,DBF4,GLYR1,MAP7D2,LOXL3,PCLO,BVES,HAS2,ARHGAP36,VSIG4,GABARAPL2,AGBL5,SMAP1,MSL1,SOWAHA,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,ADAM22,MXI1,NELL2,NF1,CNOT4,PCDH9,PDE3A,CYTL1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,MAPK9,GRAMD1C,APTX,CNTLN,PTPRG,TMEM255A,FAM66C,SH3TC2,RBBP6,ZDHHC14,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,RPL15,ZC3H14,ZNF671,ADAL,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SUPT20H,HSPA4L,FERMT1,ASAP3,HKDC1,FBXO11,FNDC3A,CNKSR2,WDR47,SLC6A8,CPEB4,CDK5RAP2,LIMCH1,CMTR2,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,KAT6B,TPM1,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,VLDLR,GUSBP1,XPO1,XRCC4,ANKS1B,EMSY,PRTFDC1,PRDM10,ST7,HNRNPA3,PHTF2,NLRP3" MicroRNA hsa-miR-320b:mirSVR_highEffct hsa-miR-320b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.34E-90 4.66E-86 8.95E-89 8.24E-88 240 1421 "ABCF1,KCNH8,SYN3,NCKAP5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,SPOP,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK13,ZBTB10,TMEM108,DPY19L3,CFLAR,KSR1,ARHGEF7,CA8,PTBP2,SLC25A14,VXN,SPAG9,CBLN1,CBR1,LDB2,CCNH,MTMR7,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CCDC144A,HDAC9,GPRASP1,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,CDKL3,ADGRV1,EYA1,NRN1,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,ANKFY1,COQ5,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,ZMAT1,B4GALNT1,SYT17,C15orf41,DISC1,ARFIP1,BRD8,DBF4,GLYR1,MAP7D2,LOXL3,PCLO,BVES,HAS2,ARHGAP36,VSIG4,GABARAPL2,AGBL5,SMAP1,MSL1,SOWAHA,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,ADAM22,MXI1,NELL2,NF1,CNOT4,PCDH9,PDE3A,CYTL1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,MAPK9,GRAMD1C,APTX,CNTLN,PTPRG,TMEM255A,FAM66C,SH3TC2,RBBP6,ZDHHC14,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,RPL15,ZC3H14,ZNF671,ADAL,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SUPT20H,HSPA4L,FERMT1,ASAP3,HKDC1,FBXO11,FNDC3A,CNKSR2,WDR47,SLC6A8,CPEB4,CDK5RAP2,LIMCH1,CMTR2,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,KAT6B,TPM1,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,VLDLR,GUSBP1,XPO1,XRCC4,ANKS1B,EMSY,PRTFDC1,PRDM10,ST7,HNRNPA3,PHTF2,NLRP3" MicroRNA hsa-miR-202:mirSVR_lowEffct hsa-miR-202:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-89 5.92E-86 1.13E-88 1.04E-87 230 1307 "ACADM,ASIC1,CLK4,ADRB2,DPY19L2P4,ZNF608,MTUS1,CASKIN1,PCDH19,RTL9,OSBPL1A,CEP126,FAM135A,OGT,DPP10,APAF1,EPB41L5,BCAS1,ASGR1,ZNF583,DNAJC27-AS1,NRP2,DST,NAE1,MTMR2,JAZF1,CLDN10,CD86,LRRFIP1,CLGN,FOXN3,CHN2,ARHGAP22,NRXN3,C4orf33,CNTN1,FAM149A,SUMF2,COL9A3,AHCTF1,MYRIP,ZFP28,SEC31B,ABCG1,CSNK1E,IPCEF1,CST3,KIAA0040,KATNAL2,DCAF8,PABPC5,ARMCX4,PITPNC1,RUSC2,DMTF1,DPH1,DPP6,DUSP9,DNAJB6,E2F5,EIF4G2,TENM1,PLEKHA1,COQ7,LRRC17,EPHB1,IGSF6,ZNF549,NRN1,SH3YL1,ACSL4,ZSCAN30,GORAB,FER,RGPD5,EFCAB2,HVCN1,APOPT1,AP4B1,TVP23A,HRASLS5,GALC,MTHFD2,GATM,ARFIP1,LYVE1,BRD8,RNPS1,GLI2,TNRC6A,KDM2B,LNX1,FUT10,PRDM5,ZNF496,CIT,RNF165,FICD,DDX19B,MIER3,ELOVL5,SYNPO,HMGCL,HNF4G,NEGR1,DHX35,LRRC75A,CELF5,C2orf72,SOWAHA,RBPJ,IL6R,INSM1,METTL21A,KCNB1,KHK,PAXBP1,NCOA7,LSS,SMAD1,MAN2A2,MAP2,ADAM11,LRP1B,MEF2C,MEST,KCTD6,MN1,SAMD5,ADAM22,MSR1,NRBP2,NEFM,NME4,NTRK2,NTRK3,PCDH9,PRTG,ZDHHC8,ABCB1,ZNF655,SNX10,RETREG1,PDZRN4,PMP22,LRP12,ING3,DRAM2,PPP2R5E,RANBP3L,PRKAB2,MAPK9,PRPSAP2,RELN,NCR3LG1,ZNF793,RBBP8,DPF2,ERI2,GTDC1,FIGN,ZFHX4,ARMC5,RORB,ADAL,PTGR2,MEG3,CLIP1,RYR3,TRAPPC13,SEMA6D,ATXN7,SEC14L1,GALNT10,SCAF8,KIF16B,FNDC3A,CNKSR2,SEC31A,ANKRD6,BTBD3,WDR47,BTBD7,ATF7IP,CDK5RAP2,MBD5,DOP1A,SOX11,KDM3A,KDM4C,IQSEC2,CLASP2,CLSTN2,POGZ,SSPO,NXT2,STAU1,DNMBP,FAM208A,SMG6,TCF4,TPCN2,FAM189A1,PCDHB6,SLC44A1,BHLHB9,R3HDM1,KAT6B,PIK3R5,NPL,RUNDC3B,TRO,TSC1,PRR18,CLHC1,VSNL1,ZNF781,PCDH20,CELF4,EMSY,STOX2,RNF103,FAM47E,UBE3B,KAT6A,RNF170,FXR1,AP3B2,GAN,PRRT4" MicroRNA hsa-miR-363:mirSVR_lowEffct hsa-miR-363:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-89 6.07E-86 1.16E-88 1.07E-87 261 1676 "VWA5B2,AS3MT,ELFN2,CCDC85A,ADD2,PWWP2A,BEND6,MTA3,HACE1,OSBPL8,PCDH10,UNC79,AMPH,LRCH2,ANK2,PKP4,APBB2,MAGEE2,DDO,PPP4R4,CASK,RGS20,CDK13,ZBTB10,NCOA1,ATP1B3,ZNF582,N4BP2L1,BACH1,FUBP1,VXN,SLC16A4,DLGAP2,CLGN,PLAA,AKAP7,PCYT1B,ARMC8,COL9A1,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,SLC35F1,SEC31B,C2CD2,CREM,AKAP12,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,KIAA0753,DDX46,SNAP91,WDR20,NR1D2,MAMLD1,EDIL3,FAM13A,EIF4G2,TENM1,STARD3NL,EIF1,EMX2,ERBB4,MRPL37,DNAJC27,CLVS1,SCML2,DLC1,RACK1,ST3GAL6,CEP78,FKTN,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,MEGF11,MEGF10,GABBR1,SIGLEC8,MTHFD2,LRRC37A6P,KIAA1841,GATM,CRCP,DBF4,ZNF638,PRRC2B,FUT10,STON1,GRM8,GSTT2,SOX21,GUCY1B1,IRAK3,ZHX1,HMGCR,LRRC75A,EID2B,FAM95B1,LRRC25,INSM1,JAK2,METTL21A,KCND2,IPO5,PAXBP1,HECTD2,NCOA7,PACRG,MAP4,MARK3,TM6SF1,MEIS1,PPM1L,AFF1,MMP16,MYH3,BEX5,NEK1,NELL2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,NUCB2,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PFKFB4,OLA1,XRN1,FAM216A,PCDH18,PMP22,EPB41L4B,PPARA,PPM1B,PPP2R5E,RANBP3L,PRKACB,EPDR1,DCHS2,LAMA1,CNTLN,PTPRG,PEX2,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,SLC25A36,ZFHX4,ELP2,STK32B,LRRK2,RPS20,RYR3,ZNF331,CCDC112,FAM192A,SEMA6D,CSRNP3,ATXN7,RASA3,SGK1,FERMT1,SHC4,FBXO11,SYBU,FAM81A,SEPHS1,ATF7IP,LMBRD1,SOX11,DOK5,HECW1,ZNF423,CDK19,MCF2L2,RBM26,ATP10B,ZC4H2,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,MTCL1,KLHL4,ATMIN,DMXL2,ZEB1,NAT16,TEK,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,CSMD1,TPM1,METTL3,PDSS1,STXBP4,TSC1,SSBP2,PLEKHH2,XRCC4,ZNF28,TRIM9,ELFN1,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,FZD3,KAT6A,FBXO36,JMJD1C,MSRB3,NETO1,FAM198A,SENP7" MicroRNA hsa-miR-26a-1*:mirSVR_highEffct hsa-miR-26a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-89 6.96E-86 1.33E-88 1.22E-87 236 1377 "ACADM,NCKAP5,KDM5D,XKR4,FMNL2,PLEKHH1,ADRA1D,BEND6,INTS2,HACE1,OSBPL1A,OSBPL8,CC2D2A,TAOK1,ADGRF5,C1QTNF3,ALCAM,FAM135A,ALK,OGT,DPP10,LRCH2,CASK,TMEFF1,ARNTL,ZBTB10,DYNLL1,ATP1A1,SLC4A4,RNF182,ADGRB3,BBS2,BID,CFLAR,DST,RAB29,KALRN,C1orf52,ABCG2,QKI,ARMC8,AHCTF1,ZFP28,ZNF385A,SLC35F1,CREM,ARHGEF10,PDE4DIP,DZIP3,ERC2,PHF14,PUM1,USP6NL,HDAC9,DCAF8,KCTD8,DAPK1,PABPC5,BRINP1,FBXL5,CHRDL1,EXOG,GRIN3A,DMD,NR1D2,DMTF1,DPYSL2,ECM2,ABCC5,DNM1L,GOLT1B,ANKRD46,RASGRP1,PHF20L1,SUGP2,AASS,PLEKHA1,C8orf37,CALCRL,RABEPK,ADGRV1,CLVS1,FAM198B,ACSL4,SCML2,CEP78,FCGR3A,FER,SYNCRIP,ST6GALNAC3,GABRG2,TRAF3IP2,GAD1,FAM120B,ERAP1,DISC1,GCNT2,SULT1C4,WASHC2A,MALT1,TCERG1,HPGDS,GLYR1,GLUL,ZNF638,ZNF782,GPD2,GRIN2C,FAM19A2,RNF165,ADAMTS6,RASSF8,EID2B,SOWAHA,IL12A,ZNF678,SLC35G1,KCND2,KIF5A,LMO2,LSAMP,MARK1,MEF2C,SRSF12,NRBP2,NEK1,NF1,SLC11A2,NRCAM,IGSF11,OCRL,CHAMP1,PCSK5,PDE4D,PFKFB2,OLA1,PIK3C2A,FAM218A,XRN1,FAM216A,PRIMPOL,SH3KBP1,MINDY2,RANBP3L,GRAMD1C,HYDIN,DIRAS2,DCHS2,SNRK,PIGG,ANKHD1,TMEM260,USP47,FAM66C,SH3TC2,ENOX1,KHDRBS2,MSANTD2,CRTAC1,ERI2,RGS4,RGS12,RIC8B,CARF,ROBO2,CCDC102B,LRRK2,MEG3,ZNF568,ZNF331,SCAF8,CHD9,FBXO11,NUBPL,SLC8A1,ZNF667,ANKRD36,SNCA,MBD5,SNRPN,SP4,PEG10,RBM26,LMO3,ATP10B,TROVE2,SSTR2,NKAIN2,NXT2,DIP2A,SULF2,KLHL7,SUPT5H,SYNE2,VPS13A,TMEM150C,SYT1,ANKRD28,TACR1,WSCD1,TCF4,SATB2,TRIM2,DOCK9,SLC19A3,PCDHB7,PCDHB3,NSD1,GPRIN3,FRYL,SIRT1,ITGB3BP,TNS1,CDK20,RGMB,SYNPO2,METTL3,ELP5,TRIO,ZNF610,CCDC14,WIPF1,XPO1,ZBTB14,CELF4,TMEM237,FSTL5,ZNF184,EML6,ANKS1B,SLC30A4,EPM2A,SMIM8,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-519b-5p:mirSVR_lowEffct hsa-miR-519b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-519c-5p:mirSVR_lowEffct hsa-miR-519c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-519a*:mirSVR_lowEffct hsa-miR-519a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-522*:mirSVR_lowEffct hsa-miR-522*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-518e*:mirSVR_lowEffct hsa-miR-518e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-523*:mirSVR_lowEffct hsa-miR-523*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-89 7.32E-86 1.38E-88 1.27E-87 251 1555 "ASIC1,NCKAP5,SYS1,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,INTS2,ZNF578,ALCAM,FAM135A,LRCH2,APBA2,APC,EPB41L5,VAT1L,TNRC6C,SEMA4G,PRX,TMEFF1,LINC00173,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,TTLL9,BACH1,BTK,CACNA1B,CALB2,PTBP2,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,DCLK1,CHN2,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,SPOCK2,HEPH,C2CD2L,ZC3H11A,DDX46,ALKBH8,PLPPR4,WDR20,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,E2F5,EBF1,FRY,FSD1L,YAF2,KMT5B,EIF4G2,CALCRL,PAN3,RAB9B,SPEG,ABCA8,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,PDLIM5,STAMBP,ZNF605,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,TCERG1,HPGDS,GNAL,PRUNE2,FUT10,CCDC184,MCHR1,TMEM121B,PCLO,GRIA2,CLASRP,FAM19A2,ZBTB49,PSIP1,HNF4G,HNMT,SMAP1,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,SLC35G1,KTN1,LAMP2,LIG4,LIMS1,MAT2A,SHC3,MEIS1,MN1,DBNL,N6AMT1,ZC3H12B,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,NALCN,PLIN1,PDZRN4,SH3KBP1,PRKAB2,GRAMD1C,SNRK,QRICH1,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,ADAL,CLIP1,ZNF331,PRCD,SCP2,SEC14L1,CASC3,FBXO11,ANKRD6,KANSL3,SLC6A11,BTBD7,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,MAPKBP1,SNRPN,MYO16,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,MTCL1,ADGRL3,TRIM2,TCF12,PCDHGB7,DOCK9,HIF3A,RNF216P1,PMS2CL,SIRT1,C18orf54,ITGB3BP,AKTIP,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,ZKSCAN5,TUBB1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZNF711,ZNF23,TRIM9,CRB2,REEP1,ANKS1B,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PHTF2,MSRB3,LAS1L,JPH3" MicroRNA hsa-miR-302d*:mirSVR_highEffct hsa-miR-302d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-89 9.72E-86 1.83E-88 1.69E-87 232 1333 "KDM5D,KLHL32,GALNT13,PWWP2A,ADRB2,ZNF608,INTS2,MTUS1,CASKIN1,NME5,C1QTNF3,ALCAM,ABCD2,FAM135A,PITPNM2,CDC42BPA,ANK2,PKP4,APBB2,MAGEE2,BCAS1,TNRC6C,PPP4R4,IGDCC4,TMEFF1,ARNTL,RGS20,ATP1B3,ZNF583,N4BP2L1,DOCK11,ADGRB3,ZNF599,SYNJ1,SCAPER,WASF1,CALB1,PTBP2,ISPD,RUNX1T1,METTL6,TIGD7,CFL2,SRSF11,NRXN3,HECTD1,SLC4A8,IGDCC3,CNRIP1,PREPL,HINFP,GDA,SNCAIP,CSF1,ARHGEF10,OSBPL3,PDE4DIP,APPL1,UBXN2A,DCAF4,RUBCN,DOCK4,HDAC9,GPRASP1,ARHGAP32,TCAF1,EARS2,KIAA0586,IST1,MYEF2,LYPD1,PLPPR4,SNAP91,CHRDL1,NR1D2,CPEB2,GOLT1B,ANKRD46,EEF1D,PHF20L1,TENM1,PLEKHA1,CALCRL,TUBD1,LRRC17,GPHN,FAM198B,TAOK3,DLC1,ST3GAL6,SLC9B2,FGF13,FGF14,FGFR1,FGFR3,SUCO,MEX3B,FOXF2,C2orf88,NBEA,FAM49B,ATP2C1,KHDRBS3,ST6GALNAC3,STAU2,ABLIM2,GABRB3,GAD1,DISC1,IGSF5,ADAM28,MALT1,DBF4,SPIN1,TNRC6A,ZNF638,FERMT2,GRIA2,PRDM5,FAM19A2,RNF165,HMGCR,HSF2,IDH3A,ZNF546,LRRCC1,JAK2,CYP27C1,LAMP2,HECTD2,SMAD1,LYPLAL1,AFDN,ZNF680,HNRNPM,P2RY13,NUCB2,CHAMP1,PAX6,PCDH9,PDCD2,PDE4D,GNG2,SNX10,RETREG1,PURG,ANKRD16,TRHDE,ING3,EPB41L4B,PPM1B,PCDHB17P,KANSL1,GRAMD1C,DIRAS2,RELN,TMEM260,ZSCAN32,PTPRB,SH3TC2,NWD1,RASGRF2,RBBP8,RADX,KHDRBS2,MSANTD2,SLC25A36,PBRM1,ZFHX4,KLHDC8A,ROBO2,RPL15,ABCA11P,RYR3,SUPT20H,SGK1,ZFP30,SHC4,FNDC3A,SEC31A,PPP4R3A,EPN2,RADIL,ATF7IP,ANKRD36,MBD5,SNRPN,PDZRN3,BDP1,ZNF423,ZC3H13,SPTAN1,CDK19,MCF2L2,ATP10B,ITPRID2,LARP4,ELOVL4,SEPT8,VPS13A,PDLIM2,TCEA1,TRIM2,ZMAT3,SLC44A1,ASXL3,ERCC6L2,TNS1,TPM1,METTL3,DCBLD1,P2RY12,ZNF781,ZNF711,ZNF17,ZNF23,ZNF45,CELF4,FSTL5,EML6,SMARCAD1,UPF3A,KCNAB1,WNK3,PLSCR4,PDSS2,EPM2A,DOCK8,JMJD1C,KLHDC1,RNF146,ST8SIA2" MicroRNA hsa-miR-320d:mirSVR_highEffct hsa-miR-320d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.16E-89 1.21E-85 2.28E-88 2.10E-87 235 1369 "ABCF1,KCNH8,SYN3,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK13,ZBTB10,TMEM108,DPY19L3,CFLAR,KSR1,CA8,PTBP2,SLC25A14,VXN,SPAG9,CBLN1,CBR1,LDB2,CCNH,MTMR7,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,ARHGEF6,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CNRIP1,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CCDC144A,HDAC9,GPRASP1,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,DLX1,RAB39B,USP3,NR1D2,DOCK2,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,CDKL3,ADGRV1,EYA1,NRN1,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,ANKFY1,COQ5,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,ZMAT1,B4GALNT1,SYT17,C15orf41,DISC1,ARFIP1,DBF4,MAP7D2,LOXL3,BVES,HAS2,ARHGAP36,VSIG4,GABARAPL2,AGBL5,NEGR1,SMAP1,MSL1,SOWAHA,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,ADAM22,MXI1,NELL2,NF1,CNOT4,PCDH9,PDE3A,CYTL1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,MAPK9,GRAMD1C,APTX,CNTLN,PTPRG,TMEM255A,SH3TC2,RBBP6,ZDHHC14,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,RPL15,ZC3H14,ZNF671,ADAL,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SUPT20H,HSPA4L,FERMT1,HKDC1,FBXO11,FNDC3A,CNKSR2,WDR47,SLC6A8,CPEB4,CDK5RAP2,LIMCH1,CMTR2,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,FBXW11,SIN3B,SATB2,ZFP90,TRIM2,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,KAT6B,TPM1,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,UBE3A,VLDLR,GUSBP1,XPO1,XRCC4,PCDH20,ANKS1B,EMSY,PRTFDC1,PRDM10,PPP1R3F,ST7,HNRNPA3,PHTF2,NLRP3" MicroRNA hsa-miR-4320:mirSVR_lowEffct hsa-miR-4320:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.30E-89 1.29E-85 2.42E-88 2.22E-87 236 1381 "SYS1,PTCHD1,MTUS1,KIAA1324,OSBPL8,CEP126,PCDH10,SYT13,APC,PPFIA3,SHROOM2,NCOA1,N4BP2L1,BBS2,CASTOR3,CACNA1G,CACNA1A,CACNA1B,CACNB4,CAMK2G,PRC1,LDB2,DCLK1,LOC730101,LARGE1,DLGAP1,SRSF11,EPS15L1,RAB33A,COL4A5,AKAP5,ABI3BP,RBM39,CRY2,SNCAIP,RGS6,CSNK1E,SUSD5,PLXNA4,PITPNM3,PPP1R16B,APPL1,UBXN2A,PNPLA8,CYBB,BOC,DOCK4,GAPVD1,RIPOR2,DCAF8,ZNF337,MATR3,IP6K1,HEPH,B3GAT3,TIAM2,FBXL5,SGSM2,USP3,DOCK2,RCAN1,DTNA,ECM2,EDN1,SEMA3D,KMT5B,IRAK4,PLEKHA1,TMEM35A,USPL1,EMX2,ENPP6,SRRM1,NCALD,DNAJC27,ADGRV1,EZH1,REEP2,F8,FER,SUCO,SEC23B,RGPD5,SLC37A3,EFCAB2,TRMO,NBEA,HVCN1,SARAF,AP4B1,GABBR1,GABRG2,DISC1,LRRC37A6P,SRCAP,COPS8,STARD3,KIAA1958,MAP7D2,WDFY3-AS2,TDRKH,GPR12,STON1,ATE1,PRDM5,PSIP1,ADAMTS6,ATOH8,MUM1,PADI2,ZHX1,VSIG4,ELOVL5,FAM95B1,RBPJ,IL6ST,SLC35G1,KCNN1,KIF5A,SYTL4,HECTD2,PIK3AP1,ADAM11,EFHB,MEF2C,MID1,MITF,BLOC1S2,NRBP2,TAGLN3,RTL5,ZNF862,NNAT,NPTX1,NRCAM,ETFRF1,PDE4D,CYTL1,NLGN3,NALCN,TMIE,CCSER2,TMEM38A,NLE1,PLCB2,EXOSC10,ING3,PPP1R1A,MAPK4,GRAMD1C,RELN,BDNF-AS,PTPRB,PTPRD,ZSCAN2,CEP97,TMEM255A,SLC25A48,FAM184A,ZDHHC14,RDX,GTDC1,RFX3,LGI2,KLHDC8A,ALG9,GSTCD,ROBO2,KIAA0895L,STK32B,HUNK,ATAT1,KCNIP3,FAM192A,CSRNP3,LRFN5,PEAR1,KIF16B,CPEB3,DZIP1,KDM4D,SLC11A1,SLC12A2,ELMO2,BTBD7,COA1,SNAP25,MBD5,KIF13A,ZNF415,SNRPN,FAM219A,TSNAXIP1,ERC1,PEG10,ZNF423,ARHGAP26,TSPYL2,CLASP2,CAMTA2,ITPRID2,NKAIN2,ZSCAN29,ADAMTS17,SYN1,COBL,ADGRL3,DMXL2,CLASP1,PCDHB3,R3HDM1,DOK6,METTL3,RUNDC3B,STXBP4,ZKSCAN5,HIRA,OSBP2,USP1,WNT7A,XRCC4,ZBTB14,ZNF28,CELF4,POLR3H,FSTL5,EVI5,URM1,SLC17A7,WNK3,KAT6A,ACTR3B,RNF170,MSRB3,SOCS4,LAS1L" MicroRNA hsa-miR-28-5p:mirSVR_lowEffct hsa-miR-28-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-89 1.44E-85 2.70E-88 2.48E-87 260 1670 "KCNH8,ASPHD1,NDRG2,ADCY6,CCDC85A,ADD2,PLEKHH1,AP2A2,ZNF608,CC2D2A,AK2,ADGRF5,PCDH10,SYT13,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,VAT1L,CDK10,IGDCC4,MARCH3,STX16,N4BP2L1,ADAM15,KSR1,SYNJ2,CASTOR3,MTMR2,KALRN,VXN,CBFA2T2,CD38,ENTPD6,LRBA,MAGI1,FOXN3,CHN1,PLEKHB1,TAOK2,RAB28,FBXO7,QKI,TMEM184B,LY86,FAM149A,WHRN,TOGARAM2,SH2B1,CRY2,CLIP3,AATK,ARHGEF10,GALNT9,VCAN,RIMS4,PDE4DIP,SLITRK5,PITPNM3,CTH,CCDC144A,DOCK4,ARHGAP32,HDAC4,IST1,SPATA2,ELMSAN1,DGCR5,HEPH,MYEF2,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DNM1,HS3ST2,DYNC1I1,CDON,DPH1,E2F6,PHC2,HIPK3,EGR3,RASA4,C3orf18,EPHB1,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,PTK2B,FCGRT,FKTN,FDFT1,ZNF589,MED12L,OLFM1,FGF11,SUCO,UBE2E3,PCYOX1,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,USP21,ZNF605,MEGF10,GAA,GABBR1,CHL1,GABRB3,DISC1,GATM,ALDH1L1,SESN1,DHRS4,RAB30,TOX3,TNRC6A,MSL3,ZNF638,ADGRA3,LILRB4,PRUNE2,PRDM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,MUM1,HMGCL,AGBL5,SHISA6,ZIC5,FAM69A,METTL21A,KCNK3,CREG2,IPO5,CYP27C1,SYTL4,SCAMP5,AFF1,TAGLN3,MYT1,NF1,NNAT,SMIM11A,NUCB2,LOC100128398,CDK18,PDE4A,PDE1B,GNG2,PFKFB2,PFKFB3,OLA1,PIK3R1,ZFYVE21,KCTD15,PURG,PRIMPOL,ING3,SH3KBP1,POLR2F,POU6F1,PPARA,PRKAB2,CEP41,MAPK4,EPDR1,GRAMD1C,MASP1,TMEM104,STK32A,PEX2,NKAIN1,TMEM231,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RGS3,RGS4,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,MCMBP,ATP8B4,NCBP3,FAM192A,CSRNP3,PRCD,SCP2,GALNT10,FERMT1,SYBU,PREX2,ARHGEF40,LGI3,GKAP1,SMARCC2,INAVA,SNRPN,KDM4C,IQSEC2,ZBTB43,RBM26,CLASP2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,JMJD6,PRRC2C,VPS13A,SYN2,DNMBP,TCF4,RPGRIP1L,SYNE1,NSD1,CCDC173,AP4E1,ASXL3,FAM124A,NPL,SMUG1,NEIL2,TRPS1,SSBP2,PRR18,RPL7L1,UBTF,CCDC14,ZNF19,REEP1,AMZ1,URM1,ST7,UBE3B,FAM198A,JPH3" MicroRNA hsa-miR-3125:mirSVR_highEffct hsa-miR-3125:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.22E-89 1.80E-85 3.37E-88 3.10E-87 265 1734 "KCNH8,GALNT16,ESYT2,ADRB2,MTA3,RTL9,OSBPL6,CC2D2A,ADGRF5,SRPX,FAM135A,OGT,ANK2,MYH7B,PARG,APC,UPRT,DDO,FAM131A,SPTBN4,RASL11B,N4BP2L1,BARD1,NRP2,ZNF599,KSR1,NAE1,JAZF1,THSD7A,KALRN,PTBP2,SLC25A14,HIP1R,NFS1,PRC1,CBR1,CBS,KRIT1,CERS5,USP6,MTMR7,ZMYM4,CDO1,TIGD7,RCBTB2,PLEKHB1,NRXN3,PPT2,CLCN3,C4orf33,CNR1,PCYT1B,AKAP6,LETMD1,SMARCAL1,SLC35F1,CRMP1,RNF14,HINFP,ANKRD44,GDA,SNCAIP,SLITRK5,RIMS2,RUBCN,CYBB,RIPOR2,ARHGAP24,DGKB,PITPNC1,KIAA0753,GSDME,FAM107B,CHRDL1,DMD,USP3,DNAH9,MED12,CDON,ACOT8,RCAN1,FAM78B,DUSP9,DNAJB6,E2F5,EBF1,FCF1,FSD1L,YAF2,PHF20L1,SUGP2,ING4,RGS17,SIRPB1,EXTL2,F8,ARMCX1,CLVS1,ZSCAN30,FGF12,FGF14,FGFR1,FHL1,ATP13A4,FAM49B,STAMBP,ATP6V1H,ERGIC3,DLL3,MSANTD4,TPPP3,OGA,GABRG2,ZNF559,C15orf41,DISC1,GATM,SRCAP,SULT1C4,KDM2B,ZNF782,FUT10,GRM8,RNF165,RABL2A,MIER3,GABARAPL2,ZDHHC15,TCEAL6,SHISA6,SMAP1,RBPJ,INPP1,NME9,KCNJ16,KIT,STXBP5,HECTD2,NCOA7,LRP1B,MEIS1,MMP16,MN1,FXYD7,SFR1,NELL2,NF1,NRCAM,SETD4,GLIPR1L2,CNTN3,PCDH9,PCSK1,PDE1C,PDE4B,ZNF655,PLCB2,PCDH18,PURG,MAPKAP1,SCHIP1,EPB41L4B,EPDR1,DIRAS2,SAMD9,CNTLN,PTCH1,MTMR10,PTPRE,TTC13,ZNF615,MARCH1,CEP97,RAD51D,NWD1,RASGRF1,RASGRF2,RADX,RET,REV3L,MRPS18A,RNASEL,TMLHE,EXD2,ALG9,CARF,ROBO1,CCDC102B,KIAA0895L,ZNF671,ATP8B4,SGSM1,MEG3,ABCA11P,KCNIP1,NCBP3,AP1AR,SATB1,CASC3,SH3GL3,KIF16B,SHC4,SLA,FAM81A,PPP4R3A,KDM4D,ARHGEF40,SLC11A1,ATF7IP,MYH15,TTC17,CMTR2,LMBRD1,SP4,HECW1,KDM4C,UNC5B,PEG10,TROVE2,CLSTN2,SSTR1,ZC4H2,SEPT3,SYNE2,ASTN2,ADGRL3,KLHL4,DMXL2,SATB2,RPGRIP1L,SYNE1,SLC19A3,PCDHAC2,PUM2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ZMAT3,ASXL3,BHLHB9,DCBLD1,SGK3,MGAT5B,VAV1,WIPF1,CLDND1,RICTOR,XRCC4,ELFN1,NDRG4,SPHK2,REEP1,SMARCAD1,PRTFDC1,NAV3,FAM13C,PHTF2,RNF170,DPF3" MicroRNA hsa-miR-1826:mirSVR_highEffct hsa-miR-1826:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.10E-89 2.29E-85 4.28E-88 3.94E-87 221 1214 "CCDC85A,GALNT13,PTCHD1,MTUS1,AGT,HACE1,OSBPL6,ARHGAP20,CARNS1,PCDH10,OGT,DPP10,DDO,TNRC6C,PPFIA3,ARNTL,CDK13,ZBTB10,NUMB,TMEM108,BARD1,ARHGEF7,PTBP2,CH25H,PRC1,LDB2,CCNH,LRBA,LRRFIP1,PPT2,CLTC,C4orf33,QKI,CNN3,AKAP7,COL4A5,TOGARAM2,MYRIP,FAM171B,CREM,RBM39,SIPA1L1,FAM169A,UBXN2A,RUBCN,USP6NL,DOCK4,GAPVD1,DCAF8,ZFYVE16,KCTD8,TMEM170A,DAPK1,SCRN1,ZNF804A,DDX46,SV2B,WDR20,DLX1,DMTF1,DPP6,DNM1L,ANKRD46,HIPK3,CNNM1,SEMA3D,TMTC1,YAF2,FAM13A,PHF20L1,ELN,CALCRL,DCTN4,EPB41L2,LRRC17,RASGRP2,RABEPK,TAOK3,DLC1,FER,FGF13,SLC37A3,NELFCD,COQ5,NBEA,SPECC1,BRSK1,MEGF11,MEGF10,GABRA3,MTHFD2,DCLK2,PCLO,GRIA2,FAM19A2,BVES,NCKAP1L,MIER3,NEGR1,SMAP1,SOWAHA,RBPJ,LRRCC1,IL12A,ZNF678,INPP5B,METTL21A,KCND2,KIT,LIG4,PAXBP1,SYTL4,MARK1,MATN3,MEIS1,MEST,MITF,COL28A1,MSR1,MYO9A,NCAM2,NEK1,NF1,CNOT4,NOVA1,DNHD1,SLC11A2,SMIM11A,NUCB2,TBC1D25,PRTG,PDE4D,FAM218A,RETREG1,GPSM2,NLE1,MTRF1L,MAPKAP1,RETREG2,EPB41L4B,SH3KBP1,PRKAB2,PRKACB,PRKCB,EPDR1,MAPK9,GDPD1,TMEM260,PTPN13,SH3TC2,REV3L,SLC25A36,NUDT11,ZFHX4,TMLHE,PNMA8A,ROBO1,RPE,SPIN3,ATP8B4,RTN1,SALL1,SUPT20H,SH3BGR,CPEB3,SHC4,CHD9,NUBPL,RCOR3,DOP1A,CDK19,SPART,CLASP2,STAU1,SEPT8,CEP68,TTBK2,NSFL1C,KLHL7,PLCB1,TMEM150C,CAMTA1,AGTPBP1,SATB2,ZEB1,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,AP4E1,ZMAT3,NACC2,R3HDM1,NPL,RUNDC3B,CA14,BCL2L13,TBC1D15,ZNF28,TRIM9,LYPD6,FSTL5,ZSCAN26,ANKS1B,ZNF225,CIAPIN1,SLC17A7,FAM47E,MPPE1,EPM2A,SMIM8,FBXO36,ADAMTSL3,JMJD1C,RNF170" MicroRNA hsa-miR-302c:mirSVR_highEffct hsa-miR-302c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.52E-89 3.09E-85 5.75E-88 5.30E-87 244 1481 "CLK4,KIAA1211,PTCHD1,ADRB2,MTUS1,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,MARK4,EIF4G3,STX16,DPY19L3,ATP6V1G2,BACH1,MPDZ,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,THSD7A,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,ABCG2,C4orf33,QKI,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,SNCAIP,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,KIAA0586,DGKG,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,E2F6,WDPCP,EDN3,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,STX2,VPS26C,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,MEGF11,IGSF5,TUBGCP4,ADAM28,GGTA1P,PPARGC1A,COPS8,TOX3,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPR12,GPR34,PCLO,UBE2QL1,ZDHHC15,SMAP1,MSL1,IDH3B,KCNN2,CYP27C1,SYTL4,HECTD2,NCOA7,LSS,ZNF667-AS1,MARK1,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,GPR137C,PCDH9,PDCD2,ZDHHC8,PLCL1,JAKMIP1,PRIMPOL,TRHDE,DRAM2,RASGEF1B,PRKACB,GRAMD1C,MASP1,SNRK,CNTLN,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,GTDC1,FIGN,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,MCMBP,RPS20,RTN1,SHC4,FBXO11,FNDC3A,NUBPL,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,INTS9,RCOR3,CMTR2,SNRPN,RBM34,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,SAMSN1,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NACC2,NR2E1,TNS1,RGMB,PPIL6,ZNF709,VLDLR,TBC1D15,PCDH20,KCNT2,TRIM9,LYPD6,LAMP5,CADM2,PRTFDC1,PRDM8,PRDM10,RNF103,FIP1L1,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-19b-3p:TargetScan hsa-miR-19b-3p TargetScan 6.04E-89 3.38E-85 6.27E-88 5.77E-87 198 970 "ABR,NCKAP5,ACTN1,KIAA1211,MTUS1,HECW2,KCTD16,OSBPL6,PCDH10,PITPNM2,CDC42BPA,LRCH2,MAP4K3,PHF12,EPB41L5,PPP4R4,CDK13,ATP2B2,BCL7A,JAZF1,CALM1,KALRN,CAST,RUNX1T1,PRC1,CBFA2T2,EVI5L,CFL2,PLAA,CLTC,QKI,CNGA3,FHL5,CNR1,CNTFR,ARMC8,CLOCK,CRMP1,GDA,CS,LRIG1,PLXNA4,APPL1,PHF14,RIMS2,PPP6R2,CCDC144A,DOCK4,ARHGAP32,GAPVD1,DCAF8,HDAC4,RASSF2,LONRF1,MAML1,IP6K1,GIT2,DNAL1,DBN1,MFAP3L,KLHL3,DLX1,ARRDC4,DTNA,EBF1,EDNRB,HIPK3,MBNL2,EGR3,PLXNC1,EIF4G2,EMX2,ERBB4,NCALD,ETV1,KATNAL1,EYA1,ACSL4,PTK2B,SCML2,DLC1,MED12L,FOXF2,FLNC,NBEA,ATP2C1,CELF1,FUT9,ARFIP1,GHR,CRCP,KDM2B,PRUNE2,GRB10,RNF165,FICD,MIER3,HLF,ELOVL5,IGF1,IL6ST,FAM69A,ITPKB,CDH20,KIT,LSAMP,MBNL1,CHIC1,MEF2C,MID1,AFF1,MN1,MYCN,NF1,OCRL,PAX6,PDE4A,PFKFB3,PIK3C2A,CCSER2,PLCL1,PURG,LRP12,PPARA,PPP2R5E,PRKACB,DIRAS2,PSD,MTMR10,PTPRD,PTPRG,MARCH1,RAD51D,RBBP8,KLHL11,CYB561D1,ROBO2,RPS6KA2,CLIP1,RTN1,RXRA,SATB1,CSRNP3,ATXN7,SCN8A,HSPA4L,FAM102A,CPEB3,FNDC3A,R3HDM2,CNKSR2,EPN2,CCDC88A,NAPB,BTBD7,CPEB4,EPC1,RCOR3,LIMCH1,KIF13A,FAM126B,CDK19,MPRIP,RGL1,DIP2A,ADAMTS17,PLCB1,ARC,ANKRD12,FBXW11,DMXL2,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,NACC2,CSMD1,RGMB,FAM155A,RICTOR,REEP1,DPYSL5,DHX33,MAP3K12,CADM2,EVI5,NAV3,FZD3,PHTF2,FBXO36,ADAMTSL3,FXR1,FRMD6" MicroRNA hsa-miR-19a-3p:TargetScan hsa-miR-19a-3p TargetScan 6.04E-89 3.38E-85 6.27E-88 5.77E-87 198 970 "ABR,NCKAP5,ACTN1,KIAA1211,MTUS1,HECW2,KCTD16,OSBPL6,PCDH10,PITPNM2,CDC42BPA,LRCH2,MAP4K3,PHF12,EPB41L5,PPP4R4,CDK13,ATP2B2,BCL7A,JAZF1,CALM1,KALRN,CAST,RUNX1T1,PRC1,CBFA2T2,EVI5L,CFL2,PLAA,CLTC,QKI,CNGA3,FHL5,CNR1,CNTFR,ARMC8,CLOCK,CRMP1,GDA,CS,LRIG1,PLXNA4,APPL1,PHF14,RIMS2,PPP6R2,CCDC144A,DOCK4,ARHGAP32,GAPVD1,DCAF8,HDAC4,RASSF2,LONRF1,MAML1,IP6K1,GIT2,DNAL1,DBN1,MFAP3L,KLHL3,DLX1,ARRDC4,DTNA,EBF1,EDNRB,HIPK3,MBNL2,EGR3,PLXNC1,EIF4G2,EMX2,ERBB4,NCALD,ETV1,KATNAL1,EYA1,ACSL4,PTK2B,SCML2,DLC1,MED12L,FOXF2,FLNC,NBEA,ATP2C1,CELF1,FUT9,ARFIP1,GHR,CRCP,KDM2B,PRUNE2,GRB10,RNF165,FICD,MIER3,HLF,ELOVL5,IGF1,IL6ST,FAM69A,ITPKB,CDH20,KIT,LSAMP,MBNL1,CHIC1,MEF2C,MID1,AFF1,MN1,MYCN,NF1,OCRL,PAX6,PDE4A,PFKFB3,PIK3C2A,CCSER2,PLCL1,PURG,LRP12,PPARA,PPP2R5E,PRKACB,DIRAS2,PSD,MTMR10,PTPRD,PTPRG,MARCH1,RAD51D,RBBP8,KLHL11,CYB561D1,ROBO2,RPS6KA2,CLIP1,RTN1,RXRA,SATB1,CSRNP3,ATXN7,SCN8A,HSPA4L,FAM102A,CPEB3,FNDC3A,R3HDM2,CNKSR2,EPN2,CCDC88A,NAPB,BTBD7,CPEB4,EPC1,RCOR3,LIMCH1,KIF13A,FAM126B,CDK19,MPRIP,RGL1,DIP2A,ADAMTS17,PLCB1,ARC,ANKRD12,FBXW11,DMXL2,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,NACC2,CSMD1,RGMB,FAM155A,RICTOR,REEP1,DPYSL5,DHX33,MAP3K12,CADM2,EVI5,NAV3,FZD3,PHTF2,FBXO36,ADAMTSL3,FXR1,FRMD6" MicroRNA hsa-miR-4324:mirSVR_lowEffct hsa-miR-4324:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.58E-89 3.68E-85 6.82E-88 6.28E-87 266 1752 "ABCF1,ASPHD1,FMNL2,PSMG3-AS1,ADD1,USP31,PTCHD1,OLMALINC,WDR35,CC2D2A,AK2,MARCH4,ZNF687,CDC42BPA,UPRT,AQP6,CDC14B,CDK13,NUMB,ZNF583,SLC2A11,ADAM15,BACH1,LINC00847,CACNA1G,CA4,CACNA1B,PTBP2,CBS,USP2,P2RX6,CD38,CDC25B,ZBED1,L3MBTL4,LARGE1,PLEKHB1,NDST3,RAB28,MAP4K4,CNN3,SUMF2,SLC4A8,TOGARAM2,ZNF385A,SEC31B,CDC42BPB,ANKRD44,CSNK1G3,SUSD5,PDE4DIP,PPP1R16B,APPL1,GREB1,ZSCAN23,CCDC144A,CYBB,ARHGAP32,RIPOR2,EARS2,ZNF337,IST1,SPOCK2,HEPH,GSDME,FAM107B,CHRDL1,EXOG,GRIN3A,DOCK2,DPH1,DPP6,ARRDC4,DTNA,DNM1L,KRBA2,HIPK3,KLHL5,PHF20L1,APH1A,MBNL2,EGR3,TMEM132E,GOLGA7,RGS17,STARD3NL,EPB41,STX2,SPEG,RASL12,RRAGB,STRADA,GTF2IRD2,TMEM164,SYNCRIP,ATP13A4,NBEA,SMC2,STAMBP,ERGIC3,STAU2,FYN,HRASLS5,GABRB3,TMEM8B,ACSS1,KIAA1841,ALDH1L1,USP19,CRCP,TNRC6A,PRUNE2,GPR12,DIDO1,RNF165,BVES,RABL2A,BACH2,HMGCL,HMGCR,AGBL5,MSL1,FAM95B1,RBPJ,IL6R,C2CD4C,KCNK3,KHK,CREG2,STXBP5,TTYH2,NCOA7,LSS,ASPRV1,MAP6,AQP11,MBD1,MEIS2,MID1,MSR1,MXI1,MYO7A,RTL5,MYT1,CCDC13,NPTX1,P2RY1,PCDH9,PCSK5,NALCN,CCSER2,RETREG1,MAPKAP1,SDK2,MBOAT7,EPB41L4B,POLG,PPM1B,PRKAB2,MAPK10,MASP1,SNRK,PIGG,NCR3LG1,ZSCAN32,PTPRO,ZSCAN2,ACSS3,CCDC40,SUSD4,NWD1,RADX,TRIM68,RET,FIGN,RGS3,RGS12,RIC8B,TMLHE,EXD2,ALG9,ROBO2,ELP2,CCDC102B,EPHA10,ARMH4,ATP8B4,LRRK2,ABCA11P,ATXN2,SCN8A,SCP2,SUPT20H,TRA2B,COPZ1,RASA3,SH3BGR,PPM1E,KIF16B,ASAP3,FBXO11,ABLIM3,PEX26,SLC9A5,NAPB,LGI3,ZNF667,CDK5RAP2,MBD5,FAM126B,USP33,HECW1,MYCBP2,PEG10,NFASC,SSTR1,NKAIN2,SSPO,ZSCAN29,CEP68,DIP2A,ADHFE1,STXBP1,CAMTA1,TAF6,EXOC7,DNMBP,ADGRL3,HIF3A,CCDC173,CYB561A3,PMS2CL,DICER1,TMEM121,KHDC1,C18orf54,AKTIP,TMEM9,ERCC6L2,TP53BP2,RGMB,SMUG1,TRIO,TRPM2,SSBP2,CLHC1,SLC35A4,UBTF,PLEKHH2,TOM1L2,VIPR2,XRCC4,ZBTB38,TMEM198,MAP3K12,EMSY,STOX2,SLC17A7,PCBP4,RGS7BP,UBE3B,FBXO36,TIGD6,RNF170,MSRB3,TTC7A" MicroRNA hsa-miR-3142:mirSVR_lowEffct hsa-miR-3142:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.62E-89 4.26E-85 7.88E-88 7.25E-87 233 1354 "ABR,ASIC1,ABHD6,EMILIN3,SYS1,ADD2,BRAP,HECW2,PCDH19,CC2D2A,HFM1,CEP126,C6orf89,SUGT1P4-STRA6LP-CCDC180,VAT1L,TMEFF1,PCDHGB4,INSYN2B,TMEM108,EIF4G3,ATP2B2,AZGP1,LINC00847,SYNJ2,FUBP1,CFAP410,KALRN,P2RX6,DGKI,CDC25B,ASIC3,MS4A7,NDST3,RAB28,FBXO7,TMEM184B,SRP14-AS1,WHRN,SLC4A8,ZNF521,CNRIP1,NECTIN3,SLC35F1,SEC31B,RBM39,CRY2,SNCAIP,PLXNA4,FAM169A,SLITRK5,KIAA0040,CYBB,BOC,ARHGAP32,DCAF8,IST1,HEPH,TMEM130,SGSM2,RAB39B,NR1D2,SLC12A6,DPH1,ACOT8,TOM1,ABCC5,EDNRB,ANKRD46,FSD1L,EGFR,GOLGA7,CALCRL,VPS13B,SPEG,DNAJC27,FCGR1A,FCGR1B,KAT8,UBE2E3,MEX3B,PCYOX1,SYNCRIP,IQCG,FLT1,CELF1,FYN,MEGF10,GABRG1,B4GALNT1,ZNF559,SEPT9,LRRC37A6P,GCNT2,LYVE1,DHRS4,TTBK1,GLI2,AIFM3,DCLK2,GPR37,CNTRL,ZNF496,CLASRP,ZBTB49,ATOH8,FAM222A,HAS2,ZHX1,ELOVL5,SYNPO,AGBL5,ZNF491,AGFG1,LRRC75A,ZIC5,CDH20,KCND1,KHK,KTN1,LIMS1,LMO2,GPR155,MAP2,MAT2A,MBD1,LRP1B,MMP16,ADAM22,MXI1,MYO6,MYT1,ZC3H12B,VWA2,CNOT4,NPTX2,SLC11A2,IGSF11,LOC100128398,P2RX7,PCDHGC3,PFKFB3,GPSM2,NLE1,ING3,CEP41,MASP1,QRICH1,CNTLN,CCDC40,FAM66C,SH3TC2,RASGRF2,RBBP6,HKR1,CRTAC1,RET,ERI2,RGS4,SLC25A36,RIC8B,CCDC82,CCDC25,ELP2,LRRK2,MEG3,ZNF568,ZNF331,MAPK12,CSRNP3,ATXN2,SMPD3,PEAR1,GALNT10,CPEB3,FUZ,DZIP1,ANKRD6,NUBPL,WDR37,SEPHS1,SLC8A1,SLC9A5,SMARCC2,CDK5RAP2,ANKRD36,INAVA,KIF13A,SNRPN,SOX11,SP4,KDM4C,UNC5B,DDN,LHPP,ITPRID2,MPRIP,CEP68,EXOC7,TBL1X,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHA5,HIF3A,KAT6B,PIK3R5,TP53BP2,NPL,TPM2,RUSC1,FAM155A,EIF4ENIF1,ZNF781,XPO1,ZNF24,TRIM9,POLR3H,DPYSL5,EMSY,FAM47E,PDSS2,UBE3B,LAS1L" MicroRNA hsa-miR-591:mirSVR_lowEffct hsa-miR-591:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-88 5.83E-85 1.08E-87 9.91E-87 223 1242 "RALGAPA1,GALNT16,ADD1,PTCHD1,SLC24A4,ZNF608,CASKIN1,SORCS2,WDR35,SRPX,PCDH10,SYT13,LRCH2,ANK2,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,EPB41L5,APOC2,TMEFF1,ARNTL,ATP2B2,N4BP2L1,MPDZ,PROM1,SYNJ2,PRMT9,C5,THSD7A,KALRN,PTBP2,SLC25A14,ARHGEF25,SYNGR3,SRSF11,RAB33A,NRXN3,DGCR9,C4orf33,MAP4K4,AKAP6,SUMF2,TOGARAM2,ZNF521,ZFP28,ZNF385A,SLC35F1,ANKRD44,CLIP3,CS,SNCAIP,LRIG1,PUM1,RIMS2,ZNF337,RASSF2,LONRF1,SPOCK2,ARMCX4,YTHDC1,TMEM130,SACS,EXOG,DMD,DYNC1I1,ACOT8,DTNA,DTNB,GOLT1B,HIPK3,FCF1,SEMA3D,EGR3,EIF4G2,PLEKHA1,RGS17,ENO2,ETV1,SIRPB1,MRVI1,RPS6KC1,RACK1,FCGR3A,FKTN,KAT8,TMEM164,NBEA,TMEM107,SMC2,UFM1,PDLIM5,ATP6V1H,STAU2,GABBR1,GALNT15,B4GALNT1,INPP5K,GPR162,SPIN1,GLYR1,LUZP2,FERMT2,PRUNE2,GPR12,PCLO,STMN2,GRIA2,PLCD4,GRIN2C,AP4S1,SOX21,FRMD3,BACH2,USP51,NEGR1,LRRC75A,MSL1,IDH3B,KCNN2,TTYH2,LIFR,LIMS1,SYTL4,NCOA7,LSS,ASPRV1,MAP2,MATN2,MEIS2,KCTD6,KITLG,MMP16,MN1,BLOC1S2,TAGLN3,TCEAL5,P2RY13,NEK1,NELL2,NF1,OPA1,PRTG,PDE1B,SERPINI1,PIK3R1,ZNF655,NLE1,PLCL1,ANKRD16,MAPKAP1,SCHIP1,RETREG2,POU6F1,MAPK4,HYDIN,MASP1,SAMD9,LAMA1,SNRK,CNTLN,TMEM260,ZSCAN32,PTPRB,EML5,PTPRE,TUG1,PPP2R3C,PID1,FAM66C,SH3TC2,KHDRBS2,RIC8B,ROBO2,TCP11L1,SCAF8,SGK1,CHD9,FNDC3A,CNKSR2,SLA,BTBD3,SEPHS1,ATF7IP,CPEB4,GKAP1,SMARCD3,SP4,RBM26,POGZ,SSTR1,STXBP1,VPS13A,PLCB1,PJA1,PDLIM2,TCF4,CLASP1,SYNE1,NSD1,HIF3A,RNF175,SIK3,AP4E1,HEY1,SMUG1,TSC1,ZKSCAN5,EIF4ENIF1,UBE2H,MTCH1,WIPF1,WRN,RICTOR,GUSBP1,XRCC4,PCDH20,TRIM9,LYPD6,POLR3H,ADAMTS9,TIGD6,MSRB3,FRMD6" MicroRNA hsa-miR-429:TargetScan hsa-miR-429 TargetScan 1.58E-88 8.84E-85 1.62E-87 1.49E-86 188 874 "HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,MAP4K3,PHF12,APAF1,CASK,ARHGDIA,CDK13,NUMB,ATP2A2,NRP2,GPR146,KSR1,FUBP1,JAZF1,CACNA2D1,RUNX1T1,ARHGEF1,DLGAP2,NOG,CFL2,CHN2,NGEF,FAM19A5,QKI,MAP4K4,CNN3,CNTFR,COL9A3,GAL3ST1,SEC31B,CLOCK,NCOR2,LRIG1,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,RIMS2,DOCK4,HDAC4,MATR3,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,HIPK3,EGR3,PLXNC1,GOLGA7,PAN3,MTSS1L,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GABRB3,COPS8,FERMT2,PARD3B,PSIP1,RASSF8,HAS2,FRMD5,BACH2,MIER3,HLF,NEGR1,AGFG1,NKD1,IL6ST,CDH20,KCNB1,KCND2,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,MXI1,MYCN,MYO9A,MYT1,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,PCDH8,PCSK5,PDPK1,GPR173,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,POU6F1,PPP2R2C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,RELN,CNNM2,PTCH1,PTPN13,CEP97,OXR1,RBBP8,FIGN,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,SCN8A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,ANKRD28,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,NACC2,CBX5,ASXL3,LRRC8A,NR2C2,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-200b-3p:TargetScan hsa-miR-200b-3p TargetScan 1.58E-88 8.84E-85 1.62E-87 1.49E-86 188 874 "HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,MAP4K3,PHF12,APAF1,CASK,ARHGDIA,CDK13,NUMB,ATP2A2,NRP2,GPR146,KSR1,FUBP1,JAZF1,CACNA2D1,RUNX1T1,ARHGEF1,DLGAP2,NOG,CFL2,CHN2,NGEF,FAM19A5,QKI,MAP4K4,CNN3,CNTFR,COL9A3,GAL3ST1,SEC31B,CLOCK,NCOR2,LRIG1,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,RIMS2,DOCK4,HDAC4,MATR3,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,HIPK3,EGR3,PLXNC1,GOLGA7,PAN3,MTSS1L,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GABRB3,COPS8,FERMT2,PARD3B,PSIP1,RASSF8,HAS2,FRMD5,BACH2,MIER3,HLF,NEGR1,AGFG1,NKD1,IL6ST,CDH20,KCNB1,KCND2,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,MXI1,MYCN,MYO9A,MYT1,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,PCDH8,PCSK5,PDPK1,GPR173,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,POU6F1,PPP2R2C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,RELN,CNNM2,PTCH1,PTPN13,CEP97,OXR1,RBBP8,FIGN,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,SCN8A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,ANKRD28,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,NACC2,CBX5,ASXL3,LRRC8A,NR2C2,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-200c-3p:TargetScan hsa-miR-200c-3p TargetScan 1.58E-88 8.84E-85 1.62E-87 1.49E-86 188 874 "HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,MAP4K3,PHF12,APAF1,CASK,ARHGDIA,CDK13,NUMB,ATP2A2,NRP2,GPR146,KSR1,FUBP1,JAZF1,CACNA2D1,RUNX1T1,ARHGEF1,DLGAP2,NOG,CFL2,CHN2,NGEF,FAM19A5,QKI,MAP4K4,CNN3,CNTFR,COL9A3,GAL3ST1,SEC31B,CLOCK,NCOR2,LRIG1,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,RIMS2,DOCK4,HDAC4,MATR3,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,HIPK3,EGR3,PLXNC1,GOLGA7,PAN3,MTSS1L,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GABRB3,COPS8,FERMT2,PARD3B,PSIP1,RASSF8,HAS2,FRMD5,BACH2,MIER3,HLF,NEGR1,AGFG1,NKD1,IL6ST,CDH20,KCNB1,KCND2,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,MXI1,MYCN,MYO9A,MYT1,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,PCDH8,PCSK5,PDPK1,GPR173,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,POU6F1,PPP2R2C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,RELN,CNNM2,PTCH1,PTPN13,CEP97,OXR1,RBBP8,FIGN,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,SCN8A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,ANKRD28,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,NACC2,CBX5,ASXL3,LRRC8A,NR2C2,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-610:mirSVR_lowEffct hsa-miR-610:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-88 9.52E-85 1.74E-87 1.61E-86 223 1245 "KLHL32,PLEKHH1,DPY19L2P4,AP2A2,RTL9,WDR35,SMIM17,CEP126,ZFAT,OGT,TNRC6C,LGR5,CDC14B,SEMA4G,PLA2G4C,STK33,ASPA,KIF1A,KSR1,MTMR3,WASF1,CA8,PTBP2,CBLN1,CD38,SEPT7,ZBED1,LOC730101,PLEKHB1,HECTD1,MAP4K4,IGLON5,AKAP7,PCYT1B,SUMF2,HAPLN1,SNCAIP,CSF1R,PITPNM3,UBXN2A,PNPLA8,CTH,RIMS2,ZSCAN23,DOCK4,KIAA0586,MAML1,IST1,TMEM170A,ARMCX4,PITPNC1,ELMSAN1,POM121,RHOBTB1,PLPPR4,SEC16A,CHRDL1,EXOG,CDON,CPEB2,DPP6,DNAJB6,EDN1,PHF20L1,EGFR,KMT5B,AASS,EIF4G1,EIF5,C3orf18,C8orf37,DCTN4,VPS13B,F8,FGF1,OLFM1,FHL1,SLC37A3,PDLIM5,STAMBP,CELF1,CHL1,GABRG1,SEPT9,SRRM4,CPLX2,GGTA1P,GLI2,RAB30,TOX3,LUZP2,GNAO1,GPD2,PRUNE2,CCDC184,GSTM5,SOX21,SMAP1,ZIC5,RBPJ,LRRCC1,IL6R,INSM1,LRRTM1,JAK2,KCNN2,KIT,KTN1,LIG4,MAP4,MAT2A,LRP1B,MEIS2,MIA2,PPM1L,AFDN,MN1,MXI1,MYO5A,NF1,DNHD1,CHAMP1,OPA1,CLDN11,TREM2,DPY19L2P2,GNG2,PFKFB2,NALCN,CCSER2,XRN1,FAM216A,POLR2F,DRAM2,POU6F1,PPARA,PPP2R2C,PPP2R5E,RANBP3L,RELN,TMEM260,ZIK1,C1orf109,PTX3,ZNF615,RAD51D,ENOX1,ZDHHC14,MSANTD2,REV3L,RIC8B,ALG9,RPE,ATP8B4,TCP11L1,LRRK2,ZFP2,PEAR1,SEC14L1,SGK1,SH3BP2,PPM1E,FERMT1,CPEB3,FHOD3,SYBU,NLGN1,DZIP1,BTBD3,EPN2,PKNOX2,SLC8A1,NAPB,TET1,GKAP1,SMARCC2,CDK5RAP2,SMARCD3,MAPKBP1,POGZ,LARP4,SS18,CEP68,KANK1,ADAMTS17,SLC37A2,TACC1,ANKRD12,MTCL1,PDLIM2,TBCEL,ZEB1,USP22,HIF3A,ERCC6L2,TPM1,C9orf85,SYNPO2,TRIO,PPIL6,SGK3,GORASP1,FLRT2,ZNF709,BCL2L13,TOM1L2,RICTOR,PCDH20,ZIC2,MKRN3,ZNF189,EMSY,EVI5,ADAMTS9,FZD3,ST7,UBE3B,KAT6A,RNF170,FXR1,GAN,FAM198A,SENP7" MicroRNA hsa-miR-605:mirSVR_highEffct hsa-miR-605:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-88 1.17E-84 2.13E-87 1.96E-86 210 1103 "PWWP2A,ADRB2,WDR35,C1QTNF3,FAM135A,OGT,LRCH2,FGD2,NT5C3B,SPTBN4,RGS20,CHRD,SLC4A4,TTLL9,RGS9,NRP2,ZNF599,DST,ST3GAL5,ARHGEF7,SCAPER,GPC2,KALRN,CAMK2B,VXN,CAST,SPAG9,RUNX1T1,CBR1,LDB2,CCNH,LRBA,CDH2,LRRFIP1,MAGI1,NDST3,QKI,AKAP7,SUMF2,ABI3BP,CLOCK,HAPLN1,CSF2RA,CSNK1G3,ERC2,UBXN2A,GREB1,DOCK4,GPRASP1,ARHGAP32,KATNAL2,GAPVD1,TCAF1,DGKG,SPATA2,KIAA0753,DLX1,NR1D2,DPP6,PDCD6IP,DTNA,DNAJB6,E2F5,EBF1,WDPCP,EDN3,FCF1,FRY,YAF2,PHF20L1,EGFR,MBNL2,TMEM132E,PAN3,CEP85L,CLVS1,TMEM132C,FCGR1A,CHST15,FGF14,AGAP3,ANKFY1,TRIM16,CELF1,ST6GALNAC3,NSG1,STAU2,ACSS1,MSTN,MMADHC,PCDH17,KDM2B,RAB40B,FUT10,LPAR4,GRIA2,DIDO1,SERP2,ATE1,FAM19A2,KAT7,LINGO1,ADAMTS6,ZDHHC15,MSL1,IDH3A,NKD1,RBPJ,JAK2,SLC35G1,KPNA5,STXBP5,STMN1,SFXN5,LMO2,HECTD2,MBD1,EFHB,AFDN,MSI1,ADAM22,ZNF92,MX1,MYT1,NEK1,NF1,NFE2L2,SLC11A2,PDCD2,OLA1,KCTD15,LRP12,PPP3CA,MASP1,APTX,PTCH1,ANKHD1,TMEM260,PTX3,TTC13,ZCWPW1,RADX,KHDRBS2,GTDC1,ZNF532,SUGCT,ALG9,CARF,ELP2,ATP8B4,ADAL,ZNF568,NCBP3,AP1AR,CSRNP3,SEC14L1,COPZ1,KIF16B,ANKRD6,FAM81A,BTBD3,EPN2,CCDC88A,SLC12A2,CPEB4,MYH15,MBD5,DOP1A,TEX2,ZBTB43,DDN,ATP10B,PBLD,POGZ,ZC4H2,DIP2A,VPS13A,ANKRD12,ADGRL3,CUX2,SYNE1,TEK,PMS2CL,SLC44A1,ERCC6L2,KAT6B,METTL3,TSN,TUBB1,EIF4ENIF1,UBE3A,FLRT2,TOM1L2,ELFN1,ATP6V0E2,FTSJ1,EMSY,PRTFDC1,LINC02210,STOX2,TMEM178A,CIAPIN1,GAL3ST3,KCNAB1,TRIM16L,FAM13C,FZD3,CASC15,JMJD1C,RNF146" MicroRNA hsa-miR-1267:mirSVR_lowEffct hsa-miR-1267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-88 1.34E-84 2.45E-87 2.26E-86 256 1637 "TMEM132B,GALNT13,BEND6,PCDH19,OSBPL1A,KIAA1324,OSBPL6,AK2,C1QTNF1,SPARCL1,SMIM17,ALCAM,SRPX,PCDH10,FAM135A,SUGT1P4-STRA6LP-CCDC180,USP37,LGR5,ARNTL,TMEM108,SLC2A11,N4BP2L1,DOCK11,ADAM23,NRP2,KALRN,CAST,LRBA,CDH2,DCLK1,NRXN3,FAM19A5,C4orf33,AKAP7,IQCK,ARMC8,RTTN,BAG4,MYRIP,ZFP28,HAPLN1,GDA,CLIP3,CS,CSF1R,SIPA1L1,PDE4DIP,RASGEF1C,FAM169A,PNPLA8,RIMS2,DOCK4,GAPVD1,HDAC4,ZNF337,TBC1D5,MATR3,DGKG,TMEM170A,BRINP1,DBI,DNAL1,PITPNC1,ARMCX2,YTHDC1,MFAP3L,DDX46,RHOBTB1,CHRDL1,DMD,DMTF1,SLC12A6,CASP8AP2,DPP6,DTNA,DNAJB6,DNM1L,GOLT1B,EDNRB,SEMA3D,FRY,YAF2,MBNL2,TNK2,RGS17,EPB41,LRRC17,RASGRP2,GPHN,VPS26C,TLR7,MRVI1,EZH1,CLVS1,RPS6KC1,TAOK3,ZNF589,SEC24B,FGF11,FGF13,POLK,IP6K2,SYNCRIP,JKAMP,PDLIM5,TPK1,ST6GALNAC3,SARAF,FAM120B,ZNF274,ZNF559,INPP5K,TUBGCP4,ARFIP1,CYP46A1,GFRA2,GHR,LYVE1,CRCP,RAB30,LUZP2,FUT10,GPER1,STMN2,TPPP,CIT,KAT7,GUCY1A1,IRAK3,RASSF8,HAS2,FRMD3,SYNPO,ICA1,MAP2,LYPLAL1,LRP1B,MEIS2,MID1,XRRA1,MYO5A,MYO9A,CCDC13,ALDH1L2,CNOT4,NOVA1,NRCAM,NUCB2,TBC1D25,PAX6,PDE4D,GPR85,PFKFB3,OLA1,SEMA5B,ZNF655,SNX10,PLCL1,PNMA3,LRP12,SCHIP1,PPP2R2B,PPP2R5E,PPP3CC,PRKAB2,MAPK4,HYDIN,RELN,WBP1L,DEF8,PIGG,PTPRD,PEX2,TTC13,CEP97,SLC25A48,FAT4,NWD1,RBBP6,DPF2,GTDC1,FIGN,PRIMA1,CCDC82,NEK11,ZNF331,SATB1,ATXN7,LRFN5,SCN8A,GALNT10,SUPT20H,FNDC3A,DZIP1,ANKRD6,ABLIM3,SLC6A8,SLC11A1,SLC14A1,CPEB4,GKAP1,LIMCH1,SNAP25,MBD5,MYO16,KDM4B,DOP1A,GLT8D1,NFASC,ATP10B,SS18,CEP68,RGL1,ADHFE1,SEPT3,SYN2,TACC1,FBXW11,DMXL2,ZFP90,TCF12,USP22,DOCK9,OBSL1,GPRIN3,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,FAM124A,NPL,TPM2,ANKRD20A2,RPL7L1,UBE3A,CCDC136,ZNF781,CLDND1,RICTOR,GUSBP1,ZBTB14,ZNF711,ZNF708,ZNF28,TRIM9,SPIRE1,SLC30A4,CADM2,SIGLEC10,KCNAB1,EPM2A,FZD3,MSRB3,NHSL1,SENP7" MicroRNA hsa-miR-431:mirSVR_lowEffct hsa-miR-431:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.89E-88 1.62E-84 2.95E-87 2.71E-86 251 1577 "CLK4,ABHD6,AS3MT,XKR4,KLHL32,ADD2,BRAP,FAHD2CP,BEND6,MTA3,KIAA1324,CC2D2A,SPARCL1,CEP126,SYT13,PDZD4,PKP4,APAF1,KCNAB2,APC,TNRC6C,USP37,MADD,TMEFF1,CCDC74A,NUMB,ATP2A2,SLC2A11,RNF182,N4BP2L1,RGS9,CFLAR,CACNA1G,CA12,CALB1,CAMK2G,ISPD,RUNX1T1,KRIT1,METTL6,ARHGEF1,C1orf52,SEPT7,LRRFIP1,CDO1,SRSF11,CBARP,PLEKHB1,EPS15L1,RAB33A,DGCR9,CLTC,SRP14-AS1,LETMD1,MAGED1,ABI3BP,TBPL1,ZNF521,RBM39,CS,CSNK1G3,GALNT9,PITPNM3,UBXN2A,RUBCN,KATNAL2,DGKB,ARMCX4,ELMO1,TMCC2,DNAH9,RPS6KL1,EDNRA,FCF1,RASGRP1,SEMA3D,TMTC1,OPTN,SUGP2,EBI3,MBNL2,KMT5B,RGS17,STARD3NL,EPB41,SLC43A2,SRRM1,MRPL37,ETV1,RASL12,GMPR2,CLVS1,TMEM132C,PTK2B,PPP1R1B,GTF2IRD2,FGF11,FGF12,FGF14,POLK,SUCO,PCYOX1,ATP13A4,WDR83,TMEM107,CGREF1,GAD1,ZNF234,IP6K3,LRRC37A6P,KIAA1841,ALDH1L1,TCERG1,COPS8,GLYR1,TOX3,TNRC6A,STARD3,ZNF638,KDM2B,STON1,GRIA2,GRM8,RNF165,GSTT2,RNFT2,GUCY1A1,ATOH8,RASSF8,FRMD3,TNFAIP8L3,MIER3,HLF,HMGCL,HMGCR,ZNF546,IL6R,KPNA5,CYP27C1,LIFR,LIMS1,HECTD2,SMAD9,MEIS2,SRSF12,P2RY13,NELL2,NUCB2,ZNF713,TREM2,PCDH8,PDE4A,PDE1B,TMOD2,PFKFB2,NLGN3,PIK3R1,CCSER2,TMEM38A,ANKRD16,PPARA,PRKACB,PKIA,DIRAS2,BCAS3,BDNF-AS,PTN,PTPRB,MARCH1,TMEM255A,CCDC40,SUSD4,NWD1,OXR1,KHDRBS2,ZMAT4,GTDC1,ZDHHC4,ZFHX4,ALG9,ROBO1,ROBO2,BAALC,ZNF671,NCBP3,ATXN2,SCN2B,SCN8A,HSPA4L,FERMT1,ST6GAL1,WDR37,ARHGEF40,SLC14A1,BTBD7,CPEB4,ZNF667,ANKRD36,SNCA,SNRPN,KDM4B,PDZD2,FNBP1,ZC3H13,RBM26,NFASC,ITPRID2,SSTR2,KLHL7,JMJD6,SLC37A2,EXOC7,PDLIM2,WSCD1,TCF4,SIN3B,DMXL2,ZFP90,CUX2,TCF12,SYNE1,SLC19A3,OBSL1,PUM2,C18orf54,GALNT17,ARL10,TIAM1,HEY1,ERCC6L2,TP53BP2,CHST5,ELP5,PPIL6,RUSC1,TTTY15,MTCH1,RBFOX3,KCNT2,ZNF74,MKRN3,CELF4,ANKS1B,LAMP5,LINC02210,HPS4,GAL3ST3,FAM47E,KAT6A,FAM219B,ZDHHC20" MicroRNA hsa-miR-1193:mirSVR_lowEffct hsa-miR-1193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.40E-88 1.90E-84 3.46E-87 3.19E-86 222 1238 "ASIC1,ACTN1,XKR4,PSMG3-AS1,GALNT13,ADD1,ADRB2,AP2A2,MTUS1,HECW2,RTL9,KIAA1324,OSBPL6,TXNDC16,SYT13,ZFAT,PI16,SUGT1P4-STRA6LP-CCDC180,APC,APLP1,MAGEE2,BCAS1,LINC00173,PCDHGB4,DYNLL1,N4BP2L1,RIPK1,ADGRB3,BARD1,NRP2,CFLAR,BMP7,IL33,CABP7,PTBP2,CAPN3,CAST,SPAG9,CCNH,ZBED1,ARHGAP33,TIGD7,DIS3L,ASIC3,PPT2,CLCN3,C4orf33,SRP14-AS1,ARHGEF6,COL9A1,SMARCAL1,SEC31B,CLOCK,ENTPD4,CRHBP,CRY2,GDA,CS,SNCAIP,LRRC3B,OSBPL3,PLXNA4,ERC2,UBXN2A,DCAF4,CCDC144A,DCAF8,RASSF2,MATR3,KCTD8,DGKG,PITPNC1,GUCD1,PLPPR4,DNM1,USP3,DOCK2,DPP6,SLC25A18,PDCD6IP,FARSB,EDN1,EDN3,MTSS1L,EPHB1,SPEG,MRPL10,ADGRV1,FAM198B,ZNF585B,FCGRT,STRADA,FDFT1,SLC9B2,FGF11,FGFR1,AMOTL2,POLK,ABLIM2,MEGF10,DENND2A,IP6K3,ZNF559,GATM,SULT1C4,DBF4,TOX3,LUZP2,CACFD1,KAT7,AP4S1,RASSF8,TOX2,MIER3,HLF,HMGCL,AGBL5,NEGR1,LRRC75A,NKD1,SCIN,ITGA7,SLC35G1,KCND1,SYTL4,MAP4,MEIS1,PPM1L,MPP2,MSI1,MSR1,MXI1,MYT1,SFR1,ALDH1L2,CNOT4,NPTX2,NRCAM,NTRK3,NUCB2,OPA1,PCDHGC3,PCDH9,PFKFB4,PLXNB1,PURG,PMP22,SCHIP1,PILRA,VSTM2L,DIRAS2,BCAS3,CYBC1,PSMA6,SNRK,QRICH1,WDR25,PTPRE,PTPRH,USP47,FAM66C,IQSEC3,CRTAC1,SLC25A36,RIC8B,ALG9,PNMA8A,MCMBP,GLDN,TCP11L1,ZNF568,SCP2,MRAS,SH3BGR,SLC6A8,ATF7IP,SLC22A4,MAST1,RCOR3,MBD5,CABCOCO1,FAM126B,TSNAXIP1,KDM3A,TEX2,DDN,NFASC,LHPP,POGZ,ITPRID2,RGL1,NSFL1C,SYN1,TACR1,ZFP90,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PMS2CL,DICER1-AS1,MTMR14,TLR4,CSMD1,KAT6B,AMACR,RUSC1,SLC35A4,ZNF708,AGMO,ADAMTS9,PDSS2,UBE3B,FBXO36,FAM219B" MicroRNA hsa-miR-29c:mirSVR_lowEffct hsa-miR-29c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-88 1.92E-84 3.49E-87 3.21E-86 257 1652 "VWA5B2,ABCF1,ACADM,CLK4,SYS1,NDRG2,FMNL2,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,SEMA6A,CARNS1,ZFAT,CDC42BPA,LRCH2,FGD2,CCDC146,KCNAB2,UPRT,PHYHD1,TNRC6C,USP37,SHROOM2,CDC14B,CDK10,ARHGDIG,MARK4,ZBTB10,DOCK11,ADAM15,SYNJ2,MTMR2,JAZF1,LDLRAD4,CA4,CACNA1A,KALRN,CAMK2G,ARHGEF25,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,B4GALT6,CNOT8,EPS15L1,CLTC,FBXO7,QKI,SULT4A1,WHRN,AKAP5,NCOR2,ARHGEF10,CSNK1E,OSBPL3,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,DCAF4,FAM131B,CYBB,HDAC9,ARHGAP32,KATNAL2,RIPOR2,HDAC4,IP6K1,BRINP1,ARMCX4,ELMSAN1,DDX46,ALKBH8,PLPPR4,WDR20,CDON,DPYSL2,ARRDC4,SEMA3D,GOLGA7,KCTD3,PLEKHA1,C8orf37,MTSS1L,ENPP6,ERCC2,NCALD,SPEG,MRPL37,CLVS1,POLR1B,FGFR1,HPCAL4,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,SMC2,TRIM16,ST6GALNAC3,STAU2,MSANTD4,ERAP1,SRCAP,PCDH17,PPARGC1A,DBF4,GLI2,STARD3,POLL,GP1BB,CCDC184,STON1,GRB10,GRIA2,C1QL4,ADAMTS13,RNF165,GSTM5,MUM1,RASSF8,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,INPP5B,KCNJ16,TTYH2,LAMP2,LIFR,SYTL4,MAT2A,AQP11,SCAMP5,MKLN1,COL28A1,COMMD5,RTL5,NEFM,NFE2L2,NFIX,OXTR,P2RY1,PALM,PAX6,CDK18,PIK3R1,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,RETREG2,WBP1L,PIGG,EML5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RDX,TRIM68,RET,ERI2,GTDC1,RGS3,RIC8B,ZFHX4,SETD5,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,ABCA11P,STX1B,SMPD3,GALNT10,KIF21A,PPM1E,FRMPD1,FNDC3A,PKNOX2,SLC6A8,SEPHS1,LGI3,TTC17,MAPKBP1,MBD5,SNRPN,DOP1A,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,ZNF302,ERBIN,CEP68,ADHFE1,STX1A,NSFL1C,ZC3H4,SUPT5H,ADAMTS17,SYN2,C12orf76,TACC1,SIN3B,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZNF346,SYNPO2,ELP5,AMACR,TUBB1,CLEC2L,UBTF,PLEKHH2,ZNF24,ZBTB38,CADM2,HPS4,GAL3ST3,TRIM16L,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-922:mirSVR_highEffct hsa-miR-922:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-88 3.07E-84 5.57E-87 5.13E-86 241 1461 "ABR,NCKAP5,ACTN1,NDRG3,BRAP,PWWP2A,FAHD2CP,AP2A1,PCDH19,KIAA1324,SMIM17,FAM135A,AMPD3,AMPH,OGT,PHF12,SUGT1P4-STRA6LP-CCDC180,NT5C3B,RGS20,CCDC74A,ZBTB10,ATP2A2,ALDH7A1,N4BP2L1,DPY19L3,ADGRB3,CFLAR,ST3GAL5,ARHGEF7,CA8,CACNA1B,CALB1,CALM1,PTBP2,CH25H,DCLK1,ZMYM4,MS4A7,MAP4K4,IQCK,AKAP6,LETMD1,TOGARAM2,ZFP28,FAM171B,GDA,TRIM69,CSF1R,CSNK1G3,SOCS5,PDE4DIP,DZIP3,UBXN2A,DCAF4,RUBCN,CYBB,GPRASP1,KATNAL2,LONRF1,IST1,DGKB,BRINP1,MYEF2,GSDME,SACS,TMCC2,HS3ST2,USP3,CPEB2,ABCC5,HIPK3,CNNM1,CELSR3,PHF20L1,APH1A,EBI3,GOLGA7,VPS13B,ENPP6,SRRM1,ETV1,ADGRV1,NRN1,F8,TAOK3,FER,BAIAP2,EVL,NELFCD,EFCAB2,PDLIM5,STAMBP,CELF1,CGREF1,CSPG5,OGA,DISC1,TUBA8,GGT7,DHRS4,TNRC6A,KCNMB4,GPD1,CCDC184,STON1,GRB10,GRIA2,RNF165,ADAMTS6,MAP4K5,ARHGAP36,HLF,VSIG4,AGBL5,MSL1,LAMP2,PAXBP1,SYTL4,NCOA7,MAP4,MAPT,MBD1,MBNL1,LRP1B,MEIS2,MN1,NCF2,NPTX1,NRCAM,SMIM11A,NTRK2,NUCB2,GPR137C,NALCN,PIK3R1,PLEC,TRHDE,STRN3,ING3,PPP2R2B,MAPK9,GRAMD1C,PSD,WBP1L,SNRK,CNTLN,TMEM260,ZSCAN32,ZIK1,PTPRD,ZSCAN2,RAD51D,ZNF493,RADX,RDX,FIGN,RGS4,SLC25A36,ALG9,ROBO2,ELP2,FBXW7,ATP8B4,KCNIP1,FAM192A,AP1AR,SAFB,SCN8A,PRCD,SCP2,CASC3,COPZ1,FERMT1,CPEB3,NLGN1,SEC31A,WDR37,CCDC88A,SLC12A2,ATF7IP,CPEB4,CDK5RAP2,IFT122,SNCA,MBD5,FAM126B,RBM34,BDP1,SPART,LMO3,ST5,ZSCAN29,ELOVL4,SEPT3,ARHGEF9,VPS13A,SYN2,SYP,MMS19,CAMTA1,MCF2L,ADGRL3,TBCEL,SYNE1,SLC19A3,TIAM1,NACC2,TMPO,C9orf85,TRIO,RUNDC3B,DCBLD1,KCNE5,ZKSCAN5,CLHC1,UCHL1,CCDC14,TBC1D15,P2RY12,WNT7A,ZNF711,ZNF24,MKRN3,REEP1,ANKS1B,SH3GLB2,SMARCAD1,PRDM10,RGS7BP,FZD3,DOCK8,PHTF2,CASC15,TIGD6,RNF170,SNX14,IFT88,DPF3,RNF146,FAM198A,JPH3" MicroRNA hsa-miR-299-5p:mirSVR_lowEffct hsa-miR-299-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.57E-88 3.11E-84 5.62E-87 5.18E-86 246 1521 "DGCR6,KCNH8,KDM5D,CCDC85A,AXIN2,BRAP,PWWP2A,BEND6,INTS2,RTL9,HFM1,C1QTNF1,SEMA6A,FAM135A,AMPH,LCORL,APC,GAS7,CDK10,SPTBN4,ATP2A2,SLC2A11,ADAM23,ADGRB3,GPC2,WASF1,KALRN,PTBP2,CAST,LDB2,CCNH,CDH2,LRRFIP1,MAGI1,DLGAP1,TBRG4,FOXN3,SOCS6,CHN1,RAB28,MAP4K4,CNGA3,PCYT1B,COL4A5,LETMD1,GAL3ST1,AHCTF1,SLC35F1,ENTPD4,RNF14,GDA,CS,SNCAIP,LRRC3B,ARHGEF10,CSNK1E,USP6NL,ARHGAP24,HDAC4,DGKB,IP6K1,DNAL1,ELMSAN1,MYEF2,KIAA0753,SNAP91,SV2B,SPOCK3,DMD,E2F5,TMTC1,SUGP2,MBNL2,RASA4,ASB3,PLEKHA1,EIF1,EPHB1,RABEPK,CDKL3,TLR7,ABCA8,ZNF585B,TAOK3,CHST15,FGF1,FGFR1,FHL1,POLK,UBE2E3,RGPD5,SLC37A3,NELFCD,COQ5,EFCAB2,ATP2C1,CELF1,CSPG5,HHIPL1,GABRB3,GABRG1,RAPGEF6,ERAP1,ALDH1L1,MSTN,BRD8,COPS8,SPIN1,TNRC6A,CBX1,DIDO1,GRIN2C,HAS2,FRMD5,HMGCR,ZDHHC15,CELF5,IDH3A,STXBP5,LIG4,SYTL4,HECTD2,SMAD1,MAP2,MARK1,CHIC1,MEST,POC1B,AFF1,AFDN,BLOC1S2,ADAM22,MYO9A,ZC3H12B,NFE2L2,NOVA1,NTRK2,OPA1,GLIPR1L2,CNTN3,PRTG,PDPK1,OLA1,ZNF655,FAM218A,JAKMIP1,PCDH18,SMIM7,PURG,STRN3,EXOSC10,PPM1B,PKIA,MAPK9,DCHS2,MTMR10,SPDL1,PTN,ZSCAN32,ZNF844,PPP2R3C,CCDC40,RAP1GDS1,OXR1,RBBP6,HKR1,KHDRBS2,MSANTD2,RDX,ZNF532,TMLHE,CARF,SEMA6D,SCP2,SEC14L1,SCAF8,SHC4,FBXO11,NLGN1,DZIP1,BTBD3,SLC8A1,SLC12A2,ATF7IP,ZNF667,SMARCA4,DMRTC1,MYH15,RCOR3,MYO16,BDP1,MYCBP2,RBM26,TROVE2,CLSTN2,ZSCAN29,CEP68,ZC3H4,SYNE2,ASTN2,TAF9,TAL1,ADGRL3,KIAA1107,MGRN1,TCF4,OBSL1,NSD1,SIK3,DNAH7,DICER1-AS1,ZFPM2,TIAM1,R3HDM1,CSMD1,TPM1,NPL,WBP2,DOK6,RGMB,NR2C2,SYNPO2,PDSS1,HSPBP1,UGT8,PLEKHH2,VLDLR,WIPF1,P2RY12,XPO1,PCDH20,ZNF711,ZNF45,LYPD6,ZNF189,ANKS1B,CADM2,LINC02210,ADAMTS9,FAM13C,FZD3,MARCH8,RTN4,PHTF2,FBXO36,KLHDC1" MicroRNA hsa-miR-1224-3p:mirSVR_lowEffct hsa-miR-1224-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.57E-88 3.12E-84 5.62E-87 5.18E-86 258 1668 "DGCR6,ASPHD1,ASIC1,C3orf14,KLHL32,GALNT16,ADCY6,GALNT13,PLEKHH1,TBC1D14,TAOK1,ALCAM,MARCH4,SYT13,ANK2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,AQP6,SEMA4G,CASK,SPTBN4,RGS20,PLA2G4C,DNAH17,MARK4,CHID1,STX16,SLC2A11,ADAM15,BBS2,CFLAR,CACNA1I,CACNA1G,GPC2,CA4,CALB2,PRC1,KYAT1,KRIT1,METTL6,P2RX6,SCARB1,AP4M1,CDC25B,CDH2,ZMYM4,LRRFIP1,TAOK2,ARHGAP22,TPP1,MAP4K4,SUMF2,LETMD1,ZFP28,SH2B1,HAPLN1,CRY2,ANKRD44,ABCG1,ARHGEF10,SUSD5,PDE4DIP,CST3,PLXNA4,GREB1,USP6NL,KIAA0408,MYADM,GAPVD1,RIPOR2,DCAF8,CENPL,IST1,AIF1L,ZBTB24,POM121,PLPPR4,SV2B,SGSM2,RAB39B,CDON,EBF1,SNX29,EDNRB,YAF2,APH1A,MRO,TMEM132E,EIF1,EPHB1,RABEPK,ERBB2,SIRPB1,HSPA12B,F5,PTK2B,FCGR3A,ZSCAN30,KAT8,PPP1R1B,ZNF589,SLC9B2,GTF2IRD2,POLR1B,FHL1,POLK,FOXF2,IP6K2,RGPD5,IQCG,NOP56,POMT1,CAMKK2,ZNF605,MSANTD4,HHIPL1,SDCBP2,MEGF11,MEGF10,DENND2A,DISC1,TUBGCP4,ADAM28,GHR,LYVE1,STON1,GRIA2,PLCD4,ADAMTS13,SERP2,RNF165,AP4S1,ATOH8,RASSF8,NCKAP1L,AGBL5,IRF8,LRRC25,RBPJ,SCIN,INPP5B,SLC35G1,KCNB1,KCNH2,KCNK3,A1BG-AS1,CYP27C1,STMN1,SMAD1,MAT2A,MMP16,MOV10,MSR1,MYO7A,MYO9A,DNHD1,SLC11A2,NTRK2,CLDN11,ZNF426,MTRF1L,ING3,RETREG2,EPB41L4B,FSD1,MINDY2,PPP1R1A,PPP3CC,MAPK4,CYBC1,TMEM104,PTPRE,TMEM231,CCDC40,ZNF793,TRIM68,RNASE1,GSTCD,CYB561D1,CCDC102B,EPHA10,ZC3H14,MCMBP,ADAL,RTN1,MAPK12,ATXN7,CASC3,MRAS,COPZ1,KIF21A,FERMT1,MYO18A,NUBPL,PEX26,BTBD3,NAPB,RCOR3,LIMCH1,SNRPN,MYO16,FAM219A,ATP10B,POGZ,ZC4H2,ZSCAN29,SEPT8,CEP68,KANK1,SEPT3,RHBDL3,NUDT10,TMEM150C,SYN2,SYP,SYPL1,SLC37A2,ASTN2,TACC1,PDLIM2,WSCD1,KIAA0930,SZT2,SLC19A3,TNS2,HIF3A,CYB561A3,C18orf54,THRA,PIK3R5,TP53BP1,NEIL2,TTTY15,FAM155A,UBTF,WIPF1,NPDC1,RICTOR,GUSBP1,LGI4,ZFP41,AGMO,ZNF74,CRB2,SPHK2,SPIRE1,SMARCAD1,SLC30A4,MAP3K12,SLC38A1,SIGLEC10,PLSCR4,DOCK8,CASC15,JMJD1C,TIGD6,IFT88,RNF146" MicroRNA hsa-miR-562:mirSVR_lowEffct hsa-miR-562:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.44E-88 3.60E-84 6.49E-87 5.98E-86 252 1595 "CLK4,PSMG3-AS1,ADCY6,CCDC85A,AXIN2,BEND6,RTL9,OSBPL1A,OSBPL8,TXNDC16,CC2D2A,SPARCL1,ALCAM,ARHGAP20,AMPD3,CCDC146,DDO,PPFIA3,SHROOM2,CASK,TMEFF1,CDK13,CCDC74A,NCOA1,ADGRB3,BBS2,KSR1,DST,SCAPER,JAZF1,CACNA1I,CACNA1G,LDLRAD4,CACNA1B,SPAG9,RUNX1T1,CBR1,USP6,CBFA2T2,DGKI,LRBA,ZMYM4,NUMBL,ARHGAP22,PLAA,TPP1,AKAP5,ABI3BP,MYRIP,CNRIP1,FAM171B,AKAP12,ANKRD44,GDA,SNCAIP,CSF2RA,LRRC3B,PHACTR3,USP6NL,CCDC144A,GPRASP1,ZFYVE16,EARS2,GIT2,PITPNC1,ELMSAN1,HEPH,MYEF2,FBXL5,ZC3H11A,GRIN3A,DMD,HS3ST2,RPS6KL1,DYNC1I1,DPP6,SLC25A18,DRP2,DTNA,AASDH,WDPCP,SEMA3D,PLEKHA1,USPL1,ENPP6,EYA1,FKTN,KAT8,GTF2IRD2,FGF13,FGF14,UBE2E3,HPCAL4,PCYOX1,FOXO3,SEMA4D,NOP56,WDR83,ATP2C1,ERGIC3,KHDRBS3,STAU2,DOT1L,CHL1,DENND2A,GALC,B4GALNT1,ERAP1,DISC1,KIAA1841,GATM,IGSF5,SULT1C4,MSTN,CSDC2,GGTA1P,MSL3,GNAL,FERMT2,PRUNE2,KAT7,SLC2A6,FRMD3,SYNPO,HNMT,ZDHHC15,FAM95B1,TJAP1,SCIN,IL6R,FAM69A,ITPKB,KCNJ16,STXBP5,KTN1,STMN1,MBNL1,LAYN,TBC1D25,CNTN3,PDE4B,PDE4D,SLC10A4,ZNF655,CCSER2,RETREG1,XRN1,PLIN1,PCDH18,ZNF426,PURG,PDZRN4,TRHDE,MBOAT7,FA2H,SH3KBP1,PPM1B,KANSL1,RASGEF1B,MAPK9,VPS13C,ANKHD1,PTN,TMEM260,STK32A,PTPRH,PTPRO,CEP97,FAT4,RBBP6,ZDHHC14,MSANTD2,RDX,GAL3ST4,RGS12,MRPS18A,RIC8B,EXD2,ARMH4,ZC3H14,ATP8B4,FAM161B,CLIP1,NCBP3,CCDC112,SATB1,ATXN2,FNIP1,FRMPD1,FERMT1,MYO18A,FNDC3A,NLGN1,PEX26,SLC8A1,ARHGEF40,ZKSCAN3,SNAP25,MBD5,SNRPN,PDZD2,SOX3,PEG10,TROVE2,ITPRID2,NKAIN2,CEP68,KANK1,PRRC2C,SYNE2,DNAJC9,CAMTA1,FBXW11,KLHL4,TRIM2,SYNE1,PHF24,PCDHB15,FRYL,DNAH7,ZFPM2,AKTIP,SLC44A1,ARL10,TIAM1,ACTR6,BHLHB9,NPL,CHST5,SYNPO2,TRPS1,UGT8,USP1,VLDLR,RICTOR,XPO1,ZNF24,KCNT2,ELFN1,FSTL5,EML6,DPYSL5,SPIRE1,SLC30A4,SLC38A1,TMEM178A,KCNAB1,DNAH10,AMN1,UBE3B,CASC15,LAS1L" MicroRNA hsa-miR-296-3p:mirSVR_lowEffct hsa-miR-296-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.24E-88 4.05E-84 7.29E-87 6.71E-86 240 1451 "ABCF1,ASPHD1,ABHD6,ADD2,PLEKHH1,KIAA1211,BEND6,MTUS1,KLHL13,RTL9,SEMA6A,AMPD3,UPRT,LGR5,AQP6,SEMA4G,PRX,ARRB2,CDK13,CHID1,ADGRB2,LINC00847,NRP2,KSR1,BMP7,ST3GAL5,ARHGEF7,BTK,MTMR2,JAZF1,BAIAP3,IL33,CA8,CALB1,CBFA2T2,SEPT7,DCLK1,ZMYM4,LARGE1,UBE2L6,PLEKHB1,NRXN3,TPP1,SULT4A1,IGLON5,ZNF385A,CRYBB1,GDA,CLIP3,CS,SEC24C,APPL1,PHF14,GREB1,RIMS2,EARS2,MATR3,DAPK1,SCRN1,HEPH,GUCD1,POM121,SV2B,MTX3,TMCC2,KIF19,SEC16A,GRIN3A,HS3ST2,USP3,DMTF1,DPH1,PDCD6IP,TMTC1,KMT5B,GOLGA7,STARD3NL,HSD17B14,MRPL37,MRPL10,DNAJC27,REEP2,CLVS1,ABCA8,KAT8,ZNF589,GORAB,OLFM1,FGF13,FHL1,EFCAB2,ATP2C1,CGREF1,OGA,MEGF10,GABBR1,GABRA3,CHL1,TMEM8B,SEPT9,LRRC37A6P,SPIN1,AIFM3,ZNF638,KCNMB4,WDFY3-AS2,ADGRA3,FUT10,ATP2B1-AS1,GRIA2,ADAMTS13,ADAMTS6,HAS2,PADI2,ZHX1,HMGCL,AGBL5,MSL1,IDH3B,ZIC5,KIT,STXBP5,PAXBP1,ZFYVE27,MAP4,MBNL1,MEIS1,KITLG,GIT1,MYO9A,ZC3H12B,SFR1,CCDC13,ALDH1L2,CNOT4,NOVA1,DNHD1,SMIM11A,NTRK2,TBC1D25,OPA1,P2RX7,CNTN3,NLGN3,PLCB2,ANKRD16,LRP12,RETREG2,PPM1B,KANSL1,GRAMD1C,HYDIN,PRPH,KLK6,DEF8,CNTLN,ELOVL2,STK32A,EML5,PTPRE,TUG1,PPP2R3C,SLC25A48,FAM66C,HKR1,ZDHHC14,PRRT2,RFX3,RGS3,MRPS18A,RNASEL,YY1AP1,KIAA0895L,MAP6D1,ZNF568,DGLUCY,ATXN2,FNIP1,SMPD3,MRAS,FBXO11,NLGN1,BTBD3,ATF7IP,SNRPN,PDZRN3,SOX15,NMNAT2,TEX2,PEG10,ZNF423,DBNDD2,TSPYL2,CLASP2,CLSTN2,ST5,APOM,SEPT8,ADHFE1,STXBP1,PLCB1,SYN1,SLC37A2,KLHL4,ZFP90,TCF12,ARHGAP9,ZFPM2,RELL2,NPL,TPM2,WBP2,RGMB,ZNF346,STXBP4,PPIL6,DCBLD1,TTC3,ZKSCAN5,CLHC1,MGAT5B,VSNL1,WIPF1,RICTOR,CRB2,TCEAL7,AMZ1,EML6,UPF3A,MAP3K12,MFF,DNALI1,SLC38A1,SEMA3B,GAL3ST3,ITM2C,EPM2A,RGS7BP,UBE3B,NETO2" MicroRNA hsa-miR-4288:mirSVR_lowEffct hsa-miR-4288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.69E-88 5.42E-84 9.73E-87 8.96E-86 247 1537 "ABR,SYN3,SYS1,ACTN1,KIAA1211,MTA3,ABCD2,CARNS1,SUGT1P4-STRA6LP-CCDC180,FAM131A,LGR5,CDC14B,ARNTL,ARRB1,NUMB,CHID1,SLC2A11,RIPK1,SYNJ2,ARHGEF7,FUBP1,CACNA1I,CACNA1A,CACNA2D1,CALB2,CABP7,ISPD,SPAG9,P2RX6,SCARB1,LRRFIP1,CLGN,CACNA2D2,NDST3,EPS15L1,TPP1,DGCR9,QKI,MAP4K4,FAM149A,WHRN,SUMF2,LETMD1,ABI3BP,SMARCAL1,TOGARAM2,CPS1,PREPL,HAPLN1,GDA,ARHGEF10,DZIP3,PHF14,GREB1,GPSM1,DOCK4,ARHGAP32,KATNAL2,SNPH,ARHGAP24,EARS2,ZNF337,LIN54,MATR3,DGKB,DAPK1,IP6K1,DGCR5,SV2B,SPOCK3,SGSM2,HS3ST2,DMTF1,PDCD6IP,DTNA,DUSP9,GOLT1B,EDNRB,MBNL2,EGR3,EIF5,CERCAM,ELN,ENPP6,SPEG,F8,CLVS1,ZNF589,FGFR1,PRKAG2,MEX3B,SEMA4D,PSD2,EFCAB2,PDLIM5,KHDRBS3,STAU2,ABLIM2,MEGF10,GABRB3,IP6K3,MTHFD2,CPLX1,ALDH1L1,WDFY3-AS2,LILRB4,GPD2,GPR12,GRIA2,PLCD4,ADAMTS13,AP4S1,ADAMTS6,ATOH8,RASSF8,PADI2,MAN1B1,ATXN2L,ZNF491,CELF5,FAM95B1,C2orf72,LRRCC1,FAM69A,INSM1,ITPKB,L1CAM,LAMP2,HECTD2,NCOA7,GPR155,MAN2A2,ZFYVE27,LYPLAL1,MEIS1,MEIS2,MID1,PPM1L,XRRA1,DBNL,ADAM22,MXI1,LAYN,ZNF862,NF1,ALDH1L2,CHAMP1,P2RX7,GPR173,NLGN3,TMIE,PIK3R1,ANKRD16,PRKAB2,PRKACB,PRKCB,MAPK9,RELN,QRICH1,MTMR10,ELOVL2,ZIK1,ZNF844,CEP97,SLC25A48,OXR1,ZDHHC14,RET,RGS3,RGS4,SLC25A36,RIC8B,PBRM1,RNASEL,RNH1,LGI2,CCDC102B,BAALC,SPIN3,ATP8B4,CLIP1,S100B,DGLUCY,SEMA6D,SCN2B,SCN8A,FNIP1,FOXRED1,FERMT1,MYO18A,R3HDM2,ST6GAL1,SLC8A1,SLC12A4,NAPB,CDK5RAP2,MBD5,KDM4B,BDP1,KDM3A,HECW1,MCF2L2,RBM26,ITPRID2,ZC4H2,NKAIN2,ZSCAN29,ADHFE1,JMJD6,ADAMTS17,TAF6,TBL1X,PHF24,USP32P1,TIAM1,TMEM9,BHLHB9,LRRC8A,C9orf85,TRIO,TRPS1,PPIL6,SSBP2,RPL7L1,UCHL1,MGAT5B,MTCH1,CLIP2,LAT2,ZIC1,ZBTB38,ZNF177,ZFAND5,CIAPIN1,NAV3,PCBP4,PLSCR4,PARP11,HRASLS,FBXO36,FAM219B,JMJD1C,TRAM2-AS1,FRMD6,IFT88,NETO1,GAN" MicroRNA hsa-miR-92a-1*:mirSVR_lowEffct hsa-miR-92a-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-87 6.04E-84 1.08E-86 9.96E-86 238 1430 "DGCR6,ABCF1,ACADM,ACHE,NCKAP5,XKR4,FMNL2,PLEKHH1,UNC5A,HECW2,MARCH4,ALK,DOC2A,OGT,LCORL,FAM131A,TNRC6C,SFMBT2,RGS20,MARCH3,MARK4,PCDHGB4,NCOA1,ATP2B2,SLC2A11,MPDZ,BMP7,SYNJ1,BTK,MYRF,BAIAP3,IL33,CACNB4,KALRN,HAP1,PTBP2,CCK,USP2,ENTPD2,C1orf52,ARHGAP33,SRSF11,NGEF,QKI,SULT4A1,IGLON5,CNR1,CNTN1,HAPLN1,CRYBB1,MROH8,VAC14-AS1,FAM169A,CTH,ZNF337,ARMCX4,C2CD2L,SGSM2,GRIN3A,DOCK2,DPH1,DRP2,RCAN1,AASDH,SEZ6L2,PHC2,APH1A,EGFR,MBNL2,EGR3,C8orf37,ENO2,IGSF6,ANKMY1,CLVS1,TBC1D16,ACSL4,PTK2B,RACK1,FKTN,BAIAP2,TMEM164,AGAP2,NOP56,SPECC1,FAM49B,TRIM16,HHIPL1,TPPP3,BRSK1,MEGF10,GABRA3,ZNF274,LRRC37A6P,GCK,GLI2,CCDC184,PLPP7,ADAMTS13,GRIN2D,PSIP1,SLC2A6,HLF,SYNPO,SHISA6,FAM95B1,MYLK2,TJAP1,KCND2,KCNF1,KCNK3,KIF5A,MBD1,KCTD6,PPM1L,COL28A1,MYO7A,MYT1,NEK1,NOVA1,IGSF11,OCRL,OGG1,ZNF827,PALM,PCDHGC3,PCSK5,CDK18,PDE1B,PFKFB4,PKM,PLEC,SLC25A23,PLTP,NECAB2,ING3,FA2H,POLR2F,FSD1,POU6F1,KLK6,CYBC1,CASTOR1,FAM66C,FAT4,RAP1GDS1,DUSP15,GTDC1,FIGN,SLC25A36,LGI2,DCUN1D2,GLDN,SEMA6D,ATXN2,ATXN7,PRCD,PEAR1,SUPT20H,TRA2B,CCDC92,SLA,DHX30,KANSL3,SLC8A1,SLC22A4,CDK5RAP2,MBD5,PDZRN3,BDP1,KDM3A,ZSWIM8,NMNAT2,UNC5B,SPTAN1,SPTB,ATP10B,ZC4H2,STAU1,STX1A,SEPT3,KLHL7,NECAB1,RHBDL3,SYN2,SYT5,MLST8,EXOC7,PDLIM2,KLHL4,WSCD1,SIN3B,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PUM2,PMS2CL,AP4E1,AKTIP,TMEM9,R3HDM1,CABIN1,CDK20,TPM2,C9orf85,SYNPO2,ELP5,AMACR,TTTY15,ZKSCAN5,UBE2H,GORASP1,ATP6V0E2,SPHK2,TCEAL7,ZNF138,ANKS1B,ZNF195,EMSY,NT5M,GDPD5,STOX2,SEMA3B,NAV3,PPP1R3F,TRIM16L,PHTF2,LAS1L,JPH3" MicroRNA hsa-miR-216a:mirSVR_highEffct hsa-miR-216a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.09E-87 6.08E-84 1.09E-86 1.00E-85 234 1383 "VWA5B2,CLK4,NCKAP5,SYS1,ADCY6,PWWP2A,DPY19L2P4,KCTD16,OGT,LRCH2,TNRC6C,LGR5,AQP6,TMEFF1,ZFYVE28,STK33,NCOA1,ATP1B3,RNF182,ATP6V0A1,BARD1,RGS9,DST,VXN,KRIT1,CCNH,LRRFIP1,MAGI1,CFL2,SOCS6,TPP1,FBXO7,FAM149A,COL9A1,ZNF521,CPS1,FAM171B,CREM,ENTPD4,VCAN,SOCS5,USP6NL,KATNAL2,GAPVD1,TBC1D5,MATR3,KIAA0586,SPOCK2,PITPNC1,SPATA2,ELMSAN1,MYEF2,POM121,NR1D2,DPP6,DPYSL2,PDCD6IP,DTNA,ECM2,DNAJB6,E2F6,EDIL3,HIPK3,SEMA3D,FAM13A,PHF20L1,MBNL2,KMT5B,EGR3,COPS4,PLEKHA1,ING4,PAN3,RCAN2,MTSS1L,ADGRV1,ARMCX1,FAM198B,FDFT1,GORAB,FGF1,POLR1B,FGF14,UBE2E3,ATP13A4,ERGIC3,MEGF10,HRASLS5,GABRA3,GAD1,GALC,ZNF234,ZNF274,DISC1,LRRC37A6P,PPARGC1A,BRD8,COPS8,MSL3,ZNF638,KDM2B,GPD2,BTN2A1,FAM19A2,AP4S1,HNF4G,TCEAL6,DHX35,IDH3A,FAM69A,NME9,JAK2,KCNB1,KCND2,KCNN1,CREG2,PAXBP1,MAP4,LYPLAL1,MEIS2,POC1B,MITF,MYO9A,ZNF862,HNRNPM,NEK1,CNOT4,DNHD1,SLC11A2,ZNF713,DPY19L2P2,PCSK5,PDE1C,GPR85,GNG2,GPSM2,PRIMPOL,ING3,EPB41L4B,PPM1B,PPP2R5E,GRAMD1C,SNRK,PIGG,PTPRG,PTPRH,PID1,TMEM255A,SUSD4,RDX,ERI2,GTDC1,RGS12,SLC25A36,RNASEL,SUGCT,DCUN1D2,ARMC5,GSTCD,SPIN3,MAP6D1,ATXN2,SCP2,FNIP1,SMPD3,SH3BGR,SH3GL3,SEC31A,ANKRD6,PREX2,DHX30,SLC6A8,SLC14A1,BTBD7,CPEB4,CDK5RAP2,ANKRD36,SNAP25,SNCA,SOX3,KDM3A,SP4,KDM4C,ZSCAN29,ELOVL4,SEPT8,TTBK2,ZC3H4,PRRC2C,SYN2,PJA1,TAF6,ADGRL3,KIAA1107,TCEA1,DMXL2,CUX2,ZEB1,RPGRIP1L,CLASP1,PCDHGA11,SYNE1,PCDHA5,CCDC173,RNF216P1,ITGB3BP,AP4E1,BHLHB9,NR2E1,KAT6B,RGMB,RUNDC3B,TRPS1,TSN,PLEKHH2,CCDC14,TBC1D15,XRCC4,MICU3,TCEAL7,ANKS1B,SLC30A4,EMSY,LINC02210,RNF103,ADAMTS9,VPS35L,FIP1L1,PDSS2,AMN1,MRPL47,RNF170,NETO1,ST8SIA2" MicroRNA hsa-miR-382:mirSVR_highEffct hsa-miR-382:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.31E-87 1.29E-83 2.31E-86 2.12E-85 234 1388 "CLK4,ACTN1,KLHL32,GALNT13,PWWP2A,KIAA1211,BEND6,RTL9,TXNDC16,TAOK1,C1QTNF3,ALCAM,FAM135A,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,BCAS1,ARNTL,PDE8B,EIF4G3,DPY19L3,ADAM23,SEC11C,ZNF599,ARHGEF7,IL33,CACNA1B,RUNX1T1,USP2,RGN,LRBA,LOC730101,TIGD7,LRWD1,CFL2,FOXN3,SOCS6,CLTC,QKI,AKAP7,IQCK,SLC4A8,CNRIP1,SLC35F1,CPS1,FAM171B,CRHBP,CSF1,PUM1,HDAC9,IST1,ZBTB24,FBXL5,DDX46,SV2B,SPOCK3,WDR20,GRIN3A,DMD,HS3ST2,DPH1,ARRDC4,DTNB,ABCC5,DNM1L,EBF1,EDN3,EDNRB,HIPK3,RASGRP1,YAF2,PHF20L1,MBNL2,TENM1,PLEKHA1,TMEM35A,RCAN2,ENPP6,SRRM1,EXTL2,EYA1,SCML2,DLC1,FDFT1,GORAB,SLC9B2,FER,AMOTL2,POLK,SUCO,IP6K2,SYNCRIP,NBEA,CELF1,OGA,ZNF234,C15orf41,KIAA1841,PPARGC1A,RAB30,STARD3,DCLK2,WDFY3-AS2,GPD2,STMN2,GRIA2,ZHX1,PACSIN2,AGBL5,NEGR1,CELF5,IFI16,SOWAHA,ZIC5,LRRCC1,ITGAM,KCNN2,IPO5,STXBP5,LMO2,SYTL4,ZFYVE27,LYPLAL1,MATN2,MATN3,MBNL1,SRSF12,MEST,MID1,MMP16,COL28A1,LAYN,MYO9A,RTL5,SFR1,IDNK,VWA2,CLDN11,OXTR,TREM2,PCDH9,PCSK5,PDPK1,GPR85,NALCN,LRP12,ING3,EPB41L4B,CCDC144B,LRRN3,PPP2R5E,PPP3CC,PKIA,CNNM2,VPS13C,TMEM260,PTPRD,PTPRE,ZNF615,FAM66C,OXR1,RASGRF2,ERI2,GTDC1,FIGN,RFX3,ROBO1,ROBO2,CCDC102B,MRAP2,ATP8B4,TCP11L1,LRRK2,TRAPPC13,ATXN2,SCP2,SGK1,KIF21A,SHC4,SYBU,ANKRD6,BTBD3,SLC6A8,SLC6A11,SNRPN,KDM3A,PEG10,RBM26,ITPRID2,SSTR1,SEPT8,CEP68,KLHL7,SYNE2,VPS13A,SYT1,COBL,CAMTA1,SYNE1,SIK3,RNF216P1,DICER1,TIAM1,ERCC6L2,FAM124A,ZNF346,SYNPO2,STXBP4,ZKSCAN5,CLHC1,SGK3,TUBB1,ZNF610,FAM155A,EIF4ENIF1,UBE2H,UBTF,USP1,VSNL1,CLDND1,XPO1,ZNF708,ZNF19,TRIM9,ZNF138,ZBTB38,REEP1,FSTL5,EML6,SMARCAD1,NAV3,PHTF2,CASC15,NETO2" MicroRNA hsa-miR-372:mirSVR_highEffct hsa-miR-372:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.31E-87 1.30E-83 2.31E-86 2.13E-85 231 1353 "ABCF1,KIAA1211,PTCHD1,MTUS1,KLHL13,AK2,C1QTNF3,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,BACH1,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,CBR1,SCARB1,ZBED1,MAGI1,CFL2,CHN2,TAOK2,ABCG2,C4orf33,ARMC8,AKAP5,ABI3BP,IGDCC3,CNRIP1,ZNF385A,SLC35F1,CPS1,ENTPD4,CRHBP,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,HDAC9,ZNF804A,ZBTB24,MYEF2,ZC3H11A,HS3ST2,DMTF1,FAM78B,DNAJB6,E2F5,E2F6,EDNRB,ANKRD46,HIPK3,YAF2,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,STX2,DNAJC27,TAOK3,CORO2B,MED12L,POLK,SUCO,HPCAL4,NELFCD,MSANTD4,IGSF5,GGTA1P,PPARGC1A,MALT1,COPS8,HPGDS,TNRC6A,GLUL,MAP7D2,GPR12,GPR34,PCLO,ATP2B1-AS1,ACOT7,ZDHHC15,MSL1,KCNN2,SYTL4,HECTD2,NCOA7,PIK3AP1,ZNF667-AS1,MARK1,SRSF12,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,ETFRF1,PCDH9,PDCD2,PDE4D,ZDHHC8,PLCL1,JAKMIP1,ZNF426,PRIMPOL,TRHDE,PSAT1,DRAM2,RASGEF1B,PRKACB,GRAMD1C,MASP1,SNRK,CNTLN,TMEM260,PTPN13,ACSM5,ZSCAN2,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,RET,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,MCMBP,RPS20,SALL1,CPEB3,SHC4,CHD9,FBXO11,FNDC3A,WDR37,PPP4R3A,SEPHS1,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,SAMSN1,RGL1,STXBP1,KLHL7,DNAJC9,PLCB1,CAMTA1,TBCEL,TCEA1,CUX2,ZEB1,TRIM2,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NACC2,NR2E1,TNS1,TP53BP2,C9orf85,RGMB,PPIL6,TSC1,VLDLR,LYPD6,LAMP5,CADM2,PRDM8,PRDM10,TMEM178A,NELFE,PLSCR4,FAM13C,MARCH8,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-664:PITA hsa-miR-664:PITA_TOP PITA 3.05E-87 1.71E-83 3.04E-86 2.80E-85 166 679 "KCNH8,ABHD6,PWWP2A,OSBPL6,OSBPL8,GPRASP2,OGT,CDC42BPA,LRCH2,PKP4,PARG,MAGEE2,CDC14B,SEMA4G,PPP4R4,RGS20,CADPS,SLC4A4,ADGRB3,BMP7,DST,SGCE,CALM1,DCLK1,ARHGAP33,DLGAP2,SOCS6,B4GALT6,SLIT2,NRXN3,QKI,CNR1,ARMC8,ABI3BP,AHCTF1,BAG4,IGDCC3,NCOR2,SEC24C,CYBB,HDAC4,LONRF1,MATR3,BRINP1,SPATA2,MYEF2,SNAP91,WDR20,DMD,DYNC1I1,DMTF1,DPYSL2,E2F5,RASGRP1,MBNL2,RGS17,EMX2,RCAN2,GPHN,SRRM1,NCALD,NRN1,SEC24B,SPSB4,SUCO,HPCAL4,STAU2,FUT9,OGA,MEGF11,GABRB3,IQGAP2,MSTN,SESN1,SPIN1,GRIA2,PTPRT,ADAMTS6,MAP4K5,BACH2,HLF,NEGR1,AGFG1,HSF2,IRF8,IPO5,LIFR,SMAD1,GPR155,MAP2,MAP4,MAT2A,MATN2,MBNL1,CHIC1,MEST,POC1B,MKLN1,HS6ST3,MXI1,NEFH,NNAT,NOVA1,IGSF11,GPR137C,PDE4D,PDPK1,GPR85,GNG2,PIK3C2A,ZNF655,CCSER2,MINDY2,CNNM2,TMEM260,PTPRD,PTPRN2,TMEM255A,USP47,ZNF793,GAL3ST4,FIGN,RFX3,RGS4,PBRM1,ZNF532,RTN1,SATB1,SCAF8,FAM102A,SH3GL3,CHD9,NLGN1,PKNOX2,CCDC88A,CPEB4,SNAP25,MBD5,KDM4B,SOX11,ZNF423,RBM26,ITPRID2,SEPT3,SYPL1,ANKRD28,TACC1,TCF4,DMXL2,ZFP90,ZEB1,TRIM2,DICER1,SIRT1,SLC44A1,NR2E1,ERCC6L2,RIMBP2,NR2C2,UBE3A,VSNL1,ZIC1,ZNF28,LYPD6,PRDM8,ST8SIA2" MicroRNA hsa-miR-302a:mirSVR_highEffct hsa-miR-302a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.44E-87 3.61E-83 6.40E-86 5.90E-85 240 1466 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,ATP6V1G2,BACH1,MPDZ,BID,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,ZNF501,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,ABCG2,C4orf33,IQCK,COL4A5,AKAP5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,ANKRD44,SNCAIP,ARHGEF10,SOCS5,CYBB,BOC,HDAC9,KIAA0586,DGKG,YTHDC1,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,E2F6,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,STX2,VPS26C,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,MEGF11,IGSF5,TUBGCP4,MSTN,ADAM28,GGTA1P,MALT1,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPR12,GPR34,PCLO,UBE2QL1,ZDHHC15,SMAP1,MSL1,IDH3B,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,P2RX7,GPR137C,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,EPB41L4B,DRAM2,RASGEF1B,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,CNTLN,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,RNH1,ZNF532,CARF,RPE,MCMBP,RPS20,RTN1,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,RGL1,STXBP1,SYNE2,DNAJC9,PLCB1,CAMTA1,ADGRL3,TBCEL,TCEA1,ZFP90,CUX2,ZEB1,SZT2,PCDHB3,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NACC2,NR2E1,TNS1,RGMB,PPIL6,ZNF709,VLDLR,XPO1,PCDH20,TRIM9,LYPD6,LAMP5,CADM2,PRTFDC1,PRDM8,PRDM10,RNF103,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-519e*:mirSVR_highEffct hsa-miR-519e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.41E-87 4.14E-83 7.35E-86 6.77E-85 243 1503 "ABCF1,SYN3,ABHD6,KLHL32,ADCY6,PLEKHH1,PWWP2A,ADRA1D,BEND6,SRPX,APAF1,PPP4R4,ZFYVE28,CHRD,NCOA1,SLC4A4,ATP1B3,ALDH7A1,DPY19L3,ADAM15,NRP2,ZNF599,CFLAR,BMPR1B,SYNJ1,ARHGEF7,CACNA1A,CACNA1B,CALB2,CALM1,PTBP2,CAST,HIP1R,SPAG9,CD38,L3MBTL4,CDO1,CLGN,ABCG2,QKI,MAP4K4,AKAP6,NCOR1,CS,VAC14-AS1,PLXNA4,DZIP3,UBXN2A,PUM1,RIMS2,USP6NL,CCDC144A,DOCK4,ARHGAP24,MATR3,PABPC5,ARMCX4,C2CD2L,DDX46,RHOBTB1,SNAP91,SACS,CHRDL1,DMD,CPEB2,DMTF1,GOLT1B,EDN1,EDN3,HIPK3,SEMA3D,YAF2,FAM13A,PHF20L1,GOLGA7,EIF4G2,COPS4,TENM1,RGS17,PAN3,LRRC17,RASGRP2,ENPP6,DENND4A,ETV1,EXTL2,ADGRV1,CLVS1,ACSL4,TAOK3,RACK1,CEP78,GORAB,SEC24B,FER,FGF12,IP6K2,SYNCRIP,RGPD5,FOXO3,SEMA4D,ATP13A4,TMEM107,SPECC1,MSANTD4,OGA,SDCBP2,MEGF11,HRASLS5,GABRB3,DISC1,ACSS1,TUBGCP4,SULT1C4,MSTN,PPARGC1A,COPS8,HPGDS,DBF4,GLYR1,ZNF638,CBX1,MAP7D2,LUZP2,GPD2,TDRKH,GRIA2,AP4S1,PSIP1,HAS2,MIER3,HNF4G,SMAP1,LRRCC1,ZNF678,FAM69A,KCND1,KCND2,KCNJ5,KIF2A,CYP27C1,CAMK2N2,HECTD2,MBD1,KCTD6,MITF,ZNF680,ZNF92,NACA,BEX5,NCAM2,NF1,DNHD1,SETD4,OPA1,CLDN11,PRTG,SEMA5B,PIK3R1,ZNF655,ZFYVE21,XRN1,MAPKAP1,FSD1,PPARA,EPDR1,CNNM2,GDPD2,MTMR10,PTN,TMEM260,PTPRD,PTPRG,CEP97,ZNF793,SUSD4,ZNF493,RBBP6,ZDHHC14,RDX,ALG9,CARF,GSTCD,NEK11,BAALC,SPIN3,ATP8B4,TCP11L1,ABCA11P,KCNIP1,SCN8A,FNIP1,CASC3,SGK1,FAM102A,HKDC1,FBXO11,WDR37,EPN2,ARHGEF40,SIRT2,RCOR3,MBD5,TMCC1,FAM126B,BDP1,RBM26,POGZ,DIP2A,SYNE2,VPS13A,TACR1,TPCN2,TRIM2,TCF12,SYNE1,PCDHB6,FAM200B,C18orf54,AP4E1,TPM1,C9orf85,RGMB,TSC1,PRR18,CCDC14,VSNL1,ZNF708,ZNF19,TRIM9,ZNF154,ZNF177,INTS3,ZXDA,CADM2,ADAMTS9,CIAPIN1,NAV3,PDSS2,RGS7BP,DNAH10,UBE3B,DPF3" MicroRNA hsa-miR-27b*:mirSVR_lowEffct hsa-miR-27b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.72E-87 4.32E-83 7.64E-86 7.04E-85 226 1303 "NDRG3,ADD1,PTCHD1,ADRB2,SLC24A4,PCDH19,HACE1,HFM1,PCDH10,FAM135A,LCORL,TNRC6C,MARCH3,ASPA,RASL11B,SLC4A4,KSR1,ARHGEF7,MTMR2,C5,CACNB4,KALRN,HIP1R,CBR1,ENTPD6,PLEKHB1,CNOT8,NDST3,RAB28,CLTC,C4orf33,SRP14-AS1,MAP4K4,CNN3,ARHGEF6,ARMC8,COL4A5,AHCTF1,CREM,GDA,LRRC3B,DZIP3,ERC2,ARHGAP32,HDAC4,EARS2,PABPC5,DNAL1,ARMCX2,DCTN1,GUCD1,POM121,KIF19,EXOG,GRIN3A,NR1D2,SLC12A6,DNAJB6,ABCC5,EBF1,HIPK3,SEMA3D,TMTC1,FRY,FAM13A,EGFR,EGR3,COPS4,TENM1,PLEKHA1,PAN3,USPL1,VPS13B,GPHN,GMPR2,MRVI1,ARMCX1,FAM198B,DLC1,FKTN,SLC9B2,FER,GTF2IRD2,FGF11,PRKAG2,FLT1,NBEA,USP21,ZNF605,CELF1,MEGF11,DISC1,CPLX2,ARFIP1,MALT1,CRCP,RAB30,TOX3,MSL3,FERMT2,GPR34,ZNF496,AP4S1,RNFT2,MIER3,HLF,HMGCL,HMGCR,TCEAL6,SHISA6,EID2B,MSL1,ZIC5,RBPJ,KNDC1,IL12A,METTL21A,CREG2,NCOA7,SMAD9,ZNF667-AS1,MBD1,MBNL1,CHST6,MEIS1,MEIS2,MMP16,ZNF680,MXI1,TCEAL5,HNRNPM,P2RY13,ZC3H12B,ALDH1L2,NNAT,CNOT4,NOVA1,SLC11A2,NUCB2,LOC100128398,SERPINI1,TMIE,XRN1,FAM216A,PRIMPOL,STRN3,ING3,PPM1B,RANBP3L,PRKAB2,MTMR10,PTPN13,PTPRB,CASTOR1,PTX3,CEP97,RBBP6,KHDRBS2,ZDHHC14,RDX,FIGN,PBRM1,CCDC102B,NEK11,ABCA11P,ATAT1,SATB1,SCN7A,SCN8A,SCP2,KIF27,KIF21A,SH3GL3,FBXO11,FNDC3A,CNKSR2,DZIP1,ANKRD6,PEX26,KANSL3,SLC14A1,NAPB,TET1,DMRTC1,RCOR3,ANKRD36,MBD5,CMTR2,SNRPN,FAM126B,MYO16,KDM4B,ZSWIM8,ATP10B,NSFL1C,NECAB1,SYNE2,VPS13A,TACR1,WSCD1,SATB2,RPGRIP1L,SYNE1,ZFPM2,TMEM9,RIMBP2,R3HDM1,TTTY15,ZKSCAN5,SGK3,ZNF709,VLDLR,WIPF1,GUSBP1,XPO1,ZIC1,MICU3,KCNT2,ANKS1B,ZNF213,EMSY,PRTFDC1,PRDM8,URM1,DOCK8,FXR1" MicroRNA hsa-miR-541:mirSVR_lowEffct hsa-miR-541:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.84E-87 4.39E-83 7.75E-86 7.14E-85 260 1713 "ASPHD1,FMNL2,TMEM132B,GALNT16,TMCC3,ADD1,PLEKHH1,AP2A2,SPOP,CEP126,SYT13,AMPD2,ZFAT,FGD2,CCDC146,LCORL,PHYHD1,TNRC6C,PPFIA3,USP37,PRX,MADD,SPTBN4,ZFYVE28,ARHGDIA,MARCH3,CCDC74A,NUMB,DYNLL1,TMEM108,ATP6V0A1,RIPK1,RGS9,BCL7A,CFLAR,KSR1,MYRF,CFAP410,CACNA1A,DDR1,KALRN,HAP1,RUNX1T1,CBS,USP2,ENTPD6,KCNAB3,CCPG1,NUMBL,CACNA2D2,FOXN3,ASIC3,TAOK2,RAB33A,CLTC,NGEF,IGLON5,CNR1,PCYT1B,FAM149A,LETMD1,COL11A2,ABI3BP,ZNF385A,ABCG1,AATK,SNCAIP,SEC24C,SLITRK5,GREB1,CYBB,MYADM,TM9SF4,INTS1,PITPNC1,SPOCK3,TMCC2,SEC16A,SLC29A4,DPH1,DPYSL2,TOM1,AASDH,MBNL2,TNK2,ELN,RABEPK,SPEG,NRN1,CHST15,FCGRT,STRADA,ZNF589,SLC9B2,FGF13,TMEM164,POLK,RGPD5,ERGIC3,TPPP3,B4GALNT1,DISC1,SEPT9,LRRC37A6P,CYP46A1,GFER,TNRC6A,MSL3,GNAO1,PRUNE2,TMEM121B,STMN2,SPACA9,ADAMTS13,GRIN2D,GRM2,GSN,GSTM5,AP4S1,RABL2A,UBE2QL1,PADI2,AGBL5,LRRC75A,SHISA6,CELF5,SMAP1,MSL1,IDH3B,RBPJ,KIAA1755,TMEM240,LRRTM1,NME9,KCNK3,KHK,LINC00634,IPO5,STMN1,NCOA7,CLEC18A,MAN2A2,MATN2,MEST,MGAT3,AFDN,GIT1,MSI1,LYRM9,MYO7A,RTL5,NF1,DNHD1,PCBP3,NTRK3,NUCB2,CDK18,PDE4B,PFKFB4,ZDHHC8,PIK3R1,FAM218A,KCTD15,PLEC,PNMA3,NECAB2,POLR2F,FSD1,PPARA,PPP3CA,NKAIN4,CEP41,MASP1,NDUFS7,WBP1L,ZSCAN2,TMEM231,CCDC40,RAP1GDS1,ENOX1,ZNF493,OXR1,RASGRF1,RASGRF2,TRIM68,KIF7,RNH1,ARMC5,ROBO2,STK32B,RYR3,DGLUCY,SEMA6D,PEAR1,GALNT10,MRAS,SH3BP2,FAM102A,FHOD3,DZIP1,FAM81A,SLC6A8,SLC11A1,KBTBD4,EPC1,CXXC4,SMARCD3,SNAP25,FAM126B,DOP1A,ZSWIM8,SPTAN1,DDN,NFASC,ATP10B,CLSTN2,ITPRID2,LARP4,SSPO,STX1A,ARHGEF9,ADAMTS17,COBL,EXOC7,ADGRL3,KIAA0930,SZT2,PCDHB15,OBSL1,PUM2,TNS2,HIF3A,CYB561A3,DICER1-AS1,TIAM1,CABIN1,RASD2,NPL,TRPM2,DCBLD1,RUSC1,CLHC1,SLC35A4,CLEC2L,GORASP1,ZNF709,BCL2L13,CLIP2,CLDND1,NPDC1,ZSCAN26,FTSJ1,ZNF213,MAP3K12,ITM2C,UBE3B,FBXO36,CASC15,RNF146,LAS1L" MicroRNA hsa-miR-642:mirSVR_lowEffct hsa-miR-642:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.07E-87 5.07E-83 8.95E-86 8.24E-85 281 1985 "ACADM,ASIC1,GALNT16,BRAP,PWWP2A,KIAA1211,PTCHD1,SLC24A4,KIAA1324,AK2,ZNF578,C1QTNF3,CARNS1,FAM135A,ALK,PDZD4,BEGAIN,PITPNM2,CCDC146,KCNAB2,VAT1L,PPFIA3,CDK10,SEMA4G,ARRB2,NUMB,INSYN2B,ATP2B2,SLC2A11,ADAM23,TTLL9,CARMIL3,BACH1,LINC00847,ZNF599,KSR1,ARHGEF7,BTK,GYG2,CA12,DDR1,PTBP2,CAMK2A,CBS,RGN,ARHGEF1,DCLK1,LRRFIP1,L3MBTL4,MAGI1,TIGD7,CLGN,RCBTB2,PLAA,PICK1,PCYT1B,FAM171B,PREPL,C2CD2,CRY2,ABCG1,SEC24C,PDE4DIP,DZIP3,ERC2,PLCXD3,RIMS2,GPSM1,DCAF4,ARHGAP32,DCAF8,ZNF337,LIN54,IST1,DAPK1,BRINP1,DNAL1,ARMCX4,MFAP3L,FBXL5,KIAA0753,RUSC2,C2CD2L,ZC3H11A,PLPPR4,SGSM2,MTX3,DLX1,DMD,DNM1,NYAP1,DNAH9,NR1D2,CASP8AP2,RCAN1,DTNA,EBF1,SEZ6L2,EDN1,HIPK3,HEYL,TMTC1,CELSR3,MRO,ING4,C3orf18,EMX2,ENO2,ERBB4,ZNF549,SPEG,ANKMY1,RASL12,ADGRV1,CLVS1,PTK2B,ZNF589,FGF1,AGAP3,FOXO3,PSD2,ZNF605,NSG1,FYB1,SDCBP2,MEGF11,CHL1,B4GALNT1,RAPGEF6,ZNF274,SIGLEC8,LRRC37A6P,GCNT2,CYP46A1,PCDH17,GPD2,FUT10,PCLO,GRIA2,DIDO1,SERP2,GRIN2C,BTN2A1,RNF165,AP4S1,GUCY1A1,RASSF8,TNFAIP8L3,ARHGAP36,HLF,HNF4G,CPT1C,AGFG1,FAM95B1,IDH3B,MYLK2,C2orf72,ITGAM,SLC35G1,CDH20,LINC00634,A1BG-AS1,KTN1,TTYH2,ASPRV1,MAN2A2,MAPT,AFDN,N6AMT1,MYO7A,NOVA1,SLC11A2,PDE1C,PDE3A,PFKFB4,OLA1,SEMA5B,ZNF655,LRP12,EXOSC10,SH3KBP1,PRKCB,FITM2,MASP1,CNNM2,BCAS3,WBP1L,PTK2,PTPRE,PTPRH,PTPRO,PID1,FAT4,ZCWPW1,RASGRF1,ZFHX4,LGI2,ALG9,PNMA8A,ROBO1,KIRREL1,SNX22,EPHA10,BAALC,KIAA0895L,GLDN,SGSM1,MEG3,HUNK,ATAT1,ATXN7,CASC3,FOXRED1,MYO18A,AMBRA1,ABLIM3,SLA,FAM214B,KANSL3,SIRT2,CDK5RAP3,SLC9A5,SLC14A1,MYH15,RCOR3,LMBRD1,FAM219A,DOP1A,PDZD2,BDP1,FNBP1,PEG10,NFASC,CLSTN2,SSTR2,SEPT3,SYT1,TAL1,TBCEL,WSCD1,TPCN2,SZT2,NAT16,DOCK9,PHF24,FRYL,CHST8,AKTIP,TMEM9,TLR4,LRRC8A,PIK3R5,SMUG1,RUNDC3B,AMACR,STXBP4,TRPS1,ANKRD20A2,UBE3A,WIPF1,LAT2,RICTOR,ZNF711,ZNF708,MKRN3,LYPD6,CELF4,PCBP1-AS1,TFIP11,MEIS3,UPF3A,DHX33,SLC30A3,PRTFDC1,GDPD5,ADAMTS9,FIP1L1,PARP11,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-3123:mirSVR_highEffct hsa-miR-3123:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.84E-87 5.51E-83 9.70E-86 8.93E-85 243 1505 "RALGAPA1,CCDC85A,GALNT13,ADD2,BRAP,KLHL13,RTL9,HACE1,ADGRF5,C1QTNF3,SMIM17,ALCAM,ARHGAP20,MARCH4,UNC79,OGT,LRCH2,ZBTB10,NUMB,SLC4A4,ZNF583,BACH1,CFLAR,WASF1,CALM1,PTBP2,SLC25A14,VXN,USP2,CD86,DGKI,MAGI1,TIGD7,COPB2,MS4A7,RAB28,NRXN3,PLAA,TPP1,MAP4K4,CNN3,CNTFR,AKAP6,SUMF2,LETMD1,COL9A3,BAG4,CLOCK,CLIP3,ARHGEF10,SOCS5,PDE4DIP,ERC2,RIMS2,RUBCN,DOCK4,TCAF1,DCAF8,DGKB,TMEM170A,PABPC5,DBN1,ZNF804A,MYEF2,C2CD2L,ZNF582-AS1,DMD,DYNC1I1,SLC12A6,PDCD6IP,DTNB,ABCC5,DNM1L,GOLT1B,E2F6,EDNRA,YAF2,PHF20L1,EGFR,ELN,TUBD1,VPS13B,EPB41L2,ETV1,PIPOX,TLR7,SIRPB1,NRN1,FAM198B,ACSL4,CEP78,FGF11,FGFR1,FLT1,ANKFY1,C2orf88,PDLIM5,ATP2C1,CELF1,STAU2,FYB1,GALC,IQGAP2,ERAP1,TUBGCP4,SULT1C4,ADAM28,GHR,GNAL,FUT10,CNTRL,DIDO1,PLCD4,COQ10A,SOX21,RNFT2,HAS2,HLF,GABARAPL2,SHISA6,SCIN,ITGAM,SLC35G1,PIK3AP1,MAP2,MEIS1,MEST,ADAM22,LYRM9,MYO6,NDP,NF1,NRCAM,SMIM11A,NTRK2,OCRL,GPR137C,PCDH9,PRTG,GPR173,ZDHHC8,GPSM2,JAKMIP1,MTRF1L,LRP12,PPP3CA,PRKACB,HYDIN,DIRAS2,RELN,CNTLN,MTMR10,TMEM260,STK32A,PPP2R3C,ZNF793,ZNF493,OXR1,RASGRF2,KHDRBS2,RDX,RFX3,SLC25A36,NUDT11,RNASEL,ZNF532,C12orf49,CCDC102B,NEK11,MCMBP,GLDN,LRRK2,ABCA11P,KCNIP1,CCDC112,AP1AR,DGLUCY,PRCD,FNIP1,PPM1E,HKDC1,CHD9,FBXO11,R3HDM2,ST6GAL1,EPN2,DHX30,SEPHS1,ATF7IP,SLC22A4,LIMCH1,MBD5,FAM126B,SP4,SPP1,NFASC,CLASP2,SSTR2,ZC4H2,NEK4,STXBP1,PRRC2C,ARHGEF9,PLCB1,TACR1,FAM208A,ADGRL3,TBCEL,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,TMEM9,TMPO,KAT6B,PIK3R5,TP53BP2,METTL3,TRIO,FAM155A,BCL2L13,CCDC14,GUSBP1,KCNT2,TRIM9,AGMO,LAMP5,EMSY,LINC02210,PPP1R3F,PLSCR4,FAM13C,FZD3,DOCK8,KAT6A,JMJD1C,KLHDC1,NETO2" MicroRNA hsa-miR-21:mirSVR_highEffct hsa-miR-21:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.13E-86 6.33E-83 1.11E-85 1.02E-84 204 1061 "RALGAPA1,KCNH8,C3orf14,FMNL2,CCDC85A,ESYT2,PTCHD1,DPY19L2P4,ZNF608,INTS2,CASKIN1,ADGRF5,OGT,DPP10,LCORL,APAF1,PPP4R4,SLC4A4,ATP1B3,ALDH7A1,N4BP2L1,BCL7A,BLM,ARHGEF7,FUBP1,BTK,MTMR2,PTBP2,KRIT1,RGN,CCPG1,CFL2,SOCS6,CNOT8,PLAA,C4orf33,CNTFR,CNTN1,ARMC8,AKAP6,ABI3BP,PREPL,GDA,TRIM69,SNCAIP,OSBPL3,SOCS5,DZIP3,KIAA0040,PHF14,ARHGAP32,RIPOR2,ARHGAP24,KCTD8,DGKB,TMEM170A,PABPC5,AIF1L,ZNF582-AS1,DMD,DTNA,DNM1L,EDIL3,EDNRB,ANKRD46,RASGRP1,FAM13A,PHF20L1,EIF4G1,PLEKHA1,C3orf18,PAN3,ENO2,RCAN2,NRN1,ARMCX1,FAM198B,ZNF461,SCML2,ST3GAL6,FGF1,POLK,ATP13A4,PDLIM5,TPK1,MSANTD4,MEGF11,CHL1,GABRG2,DISC1,SULT1C4,MSTN,MALT1,TDRKH,RASSF8,FRMD3,HNMT,NEGR1,CELF5,SOWAHA,RBPJ,LRRCC1,IL12A,SLC35G1,STXBP5,LAMP2,HECTD2,NCOA7,MATN2,MBNL1,MEIS1,MMP16,ZNF680,P2RY13,NELL2,CNTN3,DPY19L2P2,PDE4B,GNG2,ZFYVE21,GPSM2,ING3,PPP3CA,RANBP3L,MAPK10,SAMD9,PTN,TMEM260,PTPRG,PTPRN2,C1orf109,CEP97,RAD51D,RAP1GDS1,ZNF493,MSANTD2,PBRM1,NEK11,GLDN,ADAL,LRRK2,TRAPPC13,AP1AR,SATB1,FNIP1,SUPT20H,CPEB3,FBXO11,ST6GAL1,CNKSR2,SLA,BTBD3,TET1,DMRTC1,RCOR3,LIMCH1,SNAP25,USP33,PDZD2,TRERF1,KDM4C,RBM26,CLASP2,CLSTN2,ITPRID2,MPRIP,DIP2A,KANK1,SYT1,C12orf76,CAMTA1,ZFP90,TRIM2,SYNE1,PCDHB4,NSD1,CCDC173,CYB561A3,KHDC1,ZFPM2,TIAM1,TLR4,ERCC6L2,TMPO,FAM124A,NPL,PRR18,SGK3,ZNF709,CCDC14,VSNL1,LAT2,ZNF708,MICU3,KCNT2,TRIM9,ZNF189,ANKS1B,PRTFDC1,RNF103,WNK3,EPM2A,DOCK8,RTN4" MicroRNA hsa-miR-1224-5p:mirSVR_lowEffct hsa-miR-1224-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-86 7.07E-83 1.24E-85 1.14E-84 255 1654 "SYS1,NDRG2,KLHL32,CCDC85A,GALNT13,RNF157,ADD2,ADORA1,SORCS2,USP35,AMPD2,LCORL,CADPS,CDK13,CCDC74A,ZBTB10,NUMB,TMEM108,SLC4A4,STX16,N4BP2L1,RIPK1,LINC00847,BCHE,GPR146,MYRF,CACNA1B,DDR1,CACNA2D1,KALRN,HIP1R,PRC1,KYAT1,SCARB1,AP4M1,DCLK1,DLGAP1,CCPG1,NDST3,EPS15L1,ABCG2,MAP4K4,CNGA3,ARMC8,AKAP6,RCHY1,ZNF385A,FAM171B,CRY2,CST3,UBXN2A,PHF14,GREB1,DCAF4,SEC14L5,BOC,ZNF337,LONRF1,DAPK1,GIT2,MFAP3L,POM121,SGSM2,DLX1,GRIN3A,RAB39B,SLC29A4,DOCK2,SLC12A6,ACOT8,DRP2,E2F6,EDN1,CNNM1,YAF2,TMEM132E,EIF5,TLR7,SCML2,FCGRT,ZNF589,FER,OLFM1,FGF13,FGFR1,AMOTL2,POLK,NELFCD,TMEM175,SPECC1,HVCN1,ERGIC3,CGREF1,ABLIM2,ZMAT1,FAM120B,B4GALNT1,ZNF274,MTHFD2,IGSF5,LYVE1,ZNF276,RAB30,GLUL,ZNF638,HTATSF1,ADGRA3,GPD1,GRIA2,KAT7,FAM222A,FRMD3,BACH2,HNF4G,ZDHHC15,DHX35,LRRC75A,SHISA6,SOWAHA,IL6ST,ZNF678,KCND1,KCNK3,KHK,LINC00634,A1BG-AS1,IPO5,LAMP2,STMN1,PAXBP1,ASPRV1,GPR155,MAN2A2,ZFYVE27,MEIS2,MSR1,MX1,MYO7A,RTL5,ZNF862,NCAM2,NEK1,NF1,NPY,NTRK2,OCRL,LOC100128398,CLDN11,PCDH9,PCSK5,SLC10A4,ZNF655,PKD1,FAM216A,SLC25A23,ING3,FSD1,PPP2R5E,NKAIN4,MAPK4,MASP1,GDPD2,TMEM104,PIGG,CNTLN,PTK2,ZSCAN32,CASTOR1,PEX2,ZSCAN2,TUG1,PPP2R3C,SH3TC2,OXR1,ZMAT4,TRIM68,REV3L,FIGN,RGS4,RGS12,DCUN1D2,CARF,GSTCD,ROBO1,KIRREL1,ROBO2,TCP11L1,STK32B,RYR3,ZNF331,SCN2B,SCP2,SEC14L1,CASC3,SCAF8,ASAP3,MYO18A,WDR37,SLC2A5,EPN2,SIRT2,SLC9A5,SLC11A1,ELMO2,CPEB4,ARFGAP1,CDK5RAP2,INTS9,MYH15,SNCA,DOK5,ZSWIM8,SPTB,ZBTB43,NFASC,ITPRID2,NKAIN2,NXT2,KANK1,ARHGEF9,PLCB1,ARC,SYT1,SLC37A2,MTCL1,CAMTA1,TAL1,SIN3B,RPGRIP1L,CLASP1,USP32P1,AP4E1,ERCC6L2,TNS1,RASD2,NPL,ZNF346,SYNPO2,TRPS1,SSBP2,RPRM,FLRT2,ZNF709,CLDND1,XPO1,MICU3,ATP6V0E2,TMEM237,DPYSL5,INTS3,TMEM178A,EPM2A,RNF170,PRRT4,JPH3" MicroRNA hsa-miR-378b:mirSVR_lowEffct hsa-miR-378b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-86 7.09E-83 1.24E-85 1.14E-84 245 1531 "CLK4,SYS1,KDM5D,ADCY6,CCDC85A,TMCC3,ADD2,ADORA1,ADORA2A,RNF150,MTA3,PCDH19,SPARCL1,GPRASP2,AMPD2,CDC42BPA,APBA2,KCNAB2,VAT1L,ARNTL,MARK4,NUMB,N4BP2L1,MIR9-3HG,DNAJC27-AS1,KSR1,GYG2,CACNA1G,CFAP410,KALRN,PTBP2,CAMK2A,VXN,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,SOCS6,PPT2,MYL6B,FHL5,IQCK,COL4A5,ABI3BP,CLOCK,HAPLN1,CRYM,SNCAIP,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,CCDC144A,ARHGAP32,HDAC4,IST1,SPATA2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLX1,DOCK2,DMTF1,PDCD6IP,EDN1,RASGRP1,SUGP2,MBNL2,IRAK4,PLEKHA1,TMEM35A,VPS13B,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,CEP78,ZSCAN30,SEC24B,MED12L,SUCO,PCYOX1,AGAP3,PSD2,APOPT1,SARAF,GALC,RAPGEF6,IP6K3,DISC1,INPP5K,SRCAP,GPR162,GGTA1P,TTBK1,CRCP,ZNF638,CBX1,DCLK2,CLASRP,BVES,ZDHHC15,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,IL6R,TMEM240,KCND1,KCNN3,L1CAM,HECTD2,MAT2A,AQP11,AFF1,MSR1,PTOV1,MYO7A,RTL5,HNRNPM,NCF2,VWA2,DNHD1,NTRK3,PCDH9,PDCD2,PDE4A,PDE1B,GPR173,TMOD2,PFKFB4,NLGN3,ZNF655,CCSER2,XRN1,MTRF1L,PPM1B,PPP3CA,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,PEX2,NWD1,RAP1GDS1,RASGRF1,ERI2,PRIMA1,KCTD17,CARF,GSTCD,PCMTD2,SNX22,NEK11,RPL15,SPIN3,KIAA0895L,GLDN,TCP11L1,ABCA11P,HSD11B1L,AP1AR,MAPK12,CASC3,ZNF821,ANKRD6,EPN2,PKNOX2,ARHGEF40,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,SOX3,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SSTR1,LARP4,ZSCAN29,ADHFE1,STX1A,ARHGEF9,SYN2,MMS19,TACR1,MCF2L,DNMBP,FBXW11,SIN3B,TCF12,TEK,FAM200B,ZNF34,ARL10,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,AMACR,DCBLD1,RUSC1,CLHC1,SGK3,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,KCNT2,LYPD6,SH3GLB2,FTSJ1,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,FAM198A,JPH3" MicroRNA hsa-miR-452*:mirSVR_highEffct hsa-miR-452*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-86 7.23E-83 1.26E-85 1.16E-84 229 1341 "DGCR6,KCNH8,ACADM,CLK4,ADCY6,BEND6,INTS2,WDR35,ALCAM,CEP126,SYT13,AMPH,OGT,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,BCAS1,USP37,RGS20,ZBTB10,NCOA1,RASL11B,TMEM108,DPY19L3,ADAM23,TTLL9,BARD1,GPR146,CFLAR,SYNJ2,ARHGEF7,NAE1,SCAPER,JAZF1,LURAP1,CALM1,CAMK2B,CAST,RUNX1T1,CBR1,LDB2,CBFA2T2,SCARB1,ZBED1,ZMYM4,SOCS6,CHN1,NRXN3,CLTC,ARMC8,COL4A5,COL9A1,BAG4,CLOCK,NCOR1,SEC24C,ARHGEF10,VAC14-AS1,RIMS2,CYBB,DOCK4,IST1,YTHDC1,C2CD2L,DDX46,PLPPR4,SPOCK3,EXOG,RAB39B,DMD,DPH1,CASP8AP2,PDCD6IP,ECM2,EDNRA,FCF1,KLHL5,SUGP2,RASA4,DCTN4,EMX2,RASGRP2,GPHN,DENND4A,PIPOX,SIRPB1,EYA1,CEP78,PRKAG2,SUCO,FLT1,SLC37A3,NELFCD,CINP,CGREF1,STAU2,ABLIM2,ZMAT1,HRASLS5,GABRA3,GFRA2,DHRS4,STARD3,ZNF638,GPR12,GPR34,PLPP7,MAP4K5,IRAK3,AGBL5,MYLK2,ZIC5,IL6ST,KCND1,STXBP5,PAXBP1,NCOA7,SMAD9,ZFYVE27,MAT2A,LRP1B,MIA2,MID1,POC1B,AFDN,NEFH,NF1,PCBP3,NUCB2,OPRL1,CLDN11,PAX6,PCDH9,PDE4B,PDE4D,ZNF655,SNX10,FAM216A,PLCL1,ANKRD16,LRP12,SEPT4,PPM1B,HYDIN,ANKHD1,TMEM260,ZSCAN32,PTPRD,SLC25A48,ACSS3,ZNF793,FAT4,SUSD4,RADX,ZDHHC4,RIC8B,PBRM1,ZFHX4,CCDC82,SUGCT,ELP2,CCDC102B,MRAP2,EPHA10,FBXW7,ATP8B4,LRRK2,MEG3,ATXN7,SCN8A,PRCD,FERMT1,FUZ,CHD9,FBXO11,NLGN1,SEC31A,SLC6A11,SEPHS1,SLC11A1,ATF7IP,MBD5,RBM34,SP2,SP4,LMO3,NKAIN2,KANK1,STXBP1,PRRC2C,NUDT10,DNAJC9,ASTN2,TAF9,DNMBP,CUX2,ZEB1,HIF3A,SIK3,AP4E1,HEY1,TLR4,NR2E1,BEX4,RGMB,SYNPO2,TRIO,AMACR,ANKRD20A2,OSBP2,MGAT5B,VLDLR,P2RY12,CLDND1,PCDH20,ZNF23,TRIM9,FSTL5,ZSCAN26,SMARCAD1,SLC30A4,EMSY,GAL3ST3,WNK3,PDSS2,FZD3,MRPL47,RTN4,FRMD6" MicroRNA hsa-miR-1914*:mirSVR_lowEffct hsa-miR-1914*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-86 7.38E-83 1.29E-85 1.19E-84 242 1495 "ASPHD1,ASIC1,ACTN1,GALNT13,RNF157,PLEKHH1,ADRA1B,ZNF608,AK2,LRFN1,MYH7B,UPRT,FAM131A,PHYHD1,APOC1,PPFIA3,CPNE5,SEMA4G,ZFYVE28,CDK13,ATP1A3,DPY19L3,MYOM1,KSR1,BMPR1B,GPC2,CABP7,CALM1,METTL6,USP2,ENTPD2,FOXN3,PLEKHB1,FAM189A2,MAP4K4,IGLON5,CNTN1,COL11A2,ZNF385A,CLOCK,NCOR2,TRIM69,DZIP3,KIAA0040,PNPLA8,ARHGEF4,RUBCN,HDAC9,ARHGAP32,KATNAL2,CENPL,EARS2,TM9SF4,IST1,GIT2,DBN1,PITPNC1,SPATA2,SV2B,TMCC2,DNAH9,CD99L2,RPS6KL1,DMTF1,SLC25A18,ACOT8,SEZ6L2,EDN1,EGR3,EMX2,ENO2,EPB41L2,DENND4A,MRPL37,ETV1,ANKMY1,F5,CHST15,KAT8,PPP1R1B,SUCO,PCYOX1,EVL,NELFCD,DCTN2,CGREF1,NEURL4,IQGAP2,DISC1,KIAA1841,GCNT2,SRCAP,MSTN,CYP46A1,GHR,TTBK1,TCERG1,CCDC184,GRIN2C,KAT7,ZBTB49,RABL2A,FRMD5,MAN1B1,ATXN2L,ARHGAP36,ELOVL5,AGBL5,HSPA1L,FAM95B1,LRRCC1,DISP2,INPP5B,KCNK3,LAMP2,LSS,GPR155,ZFYVE27,MAPT,MBP,SHC3,MGAT3,MITF,COL28A1,MSI1,PTOV1,MYO7A,NEFH,VWA2,NOVA2,DNHD1,PCBP3,NTRK2,P2RY1,CDK18,PDPK1,GNG2,TMIE,ZNF655,PLCB2,PLTP,PLXNB1,NECAB2,C19orf57,SLC26A11,MASP1,CNTLN,TMEM231,RASGRF1,RGS12,RNASE1,SETD5,CYB561D1,KIRREL1,SNX22,KIAA0895L,TCP11L1,MEG3,HSD11B1L,CLIP1,STX1B,SEMA6D,SCP2,SEC14L1,FOXRED1,MRAS,CPEB3,CHD9,FHOD3,ST6GAL1,SLA,PPP4R3A,FAM214B,PKNOX2,SLC6A8,SLC8A1,ARHGEF40,SLC11A1,SLC12A2,SMARCA4,SMARCD3,ANKRD36,ERC1,ZC3H13,MCF2L2,NFASC,SSTR1,SSTR2,DIP2A,STXBP1,JMJD6,SYN1,SYP,CAMTA1,MLST8,TAL1,ATMIN,ZEB1,TPCN2,DOCK9,PHF24,NSD1,HIF3A,RNF216P1,DICER1,THRA,NR2E1,RIMBP2,PRRT1,CABIN1,TPM1,TPM2,C9orf85,RGMB,ZNF346,PPIL6,DCBLD1,TSN,SSBP2,TTTY15,HIRA,MTCH1,VIPR2,VLDLR,CLIP2,ZNF70,NDRG4,CELF4,ZBTB38,ANKS1B,SH3GLB2,GAL3ST3,PARP11,ST7,UBE3B,HNRNPA3,PHTF2,TRAM2-AS1,RNF170,ADAMTS10,DPF3,LAS1L" MicroRNA hsa-miR-4268:mirSVR_lowEffct hsa-miR-4268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-86 8.42E-83 1.47E-85 1.35E-84 260 1718 "DGCR6,KCNH8,NCKAP5,ADCY6,ADD1,ADORA1,PTCHD1,OSBPL6,WDR35,ARHGAP20,CARNS1,BEGAIN,AMPD2,AMPD3,EP400,UPRT,NT5C3B,PHYHD1,PPFIA3,ASGR1,ATP1A3,SLC4A4,ADAM15,AZGP1,BCHE,DNAJC27-AS1,CFLAR,DST,SYNJ2,MYRF,CA4,CAST,HIP1R,CBR1,CLDN10,CCNT1,CBFA2T2,DGKI,LOC730101,ASIC3,TAOK2,SRP14-AS1,ARHGEF6,CNTFR,CNTN1,IQCK,PCYT1B,ARMC8,CABP1,SUMF2,LETMD1,MYRIP,IGDCC3,CRMP1,CLIP3,CSF1,CSF1R,ARHGEF10,APPL1,PHF14,EARS2,DAPK1,B3GAT3,RUSC2,C2CD2L,KIAA0319,DDX46,SV2B,GRIN3A,DNM1,NYAP1,NR1D2,DOCK2,DMTF1,RCAN1,DTNB,TOM1,MAMLD1,DNM1L,E2F6,HIPK3,FAM13A,C8orf37,EPHB1,ENPP6,RASL12,SIRPB1,ZNF461,TBC1D16,TMEM132C,PTK2B,FCGRT,STRADA,FECH,MED12L,AMOTL2,SUCO,MEX3B,FLT1,NOP56,WDR83,SPECC1,PDLIM5,CELF1,CGREF1,DOT1L,OGA,NEURL4,GALNT15,GABRG1,GAD1,RAPGEF6,ALDH1L1,GCNT2,GDF9,GFER,DHRS4,CRCP,GLI2,RAB30,ZNF638,GNAO1,PRUNE2,CCDC184,STON1,TMEM121B,PCLO,STMN2,C1QL4,GRM2,GSTM5,RNFT2,ADAMTS6,TNFAIP8L3,HNMT,CPT1C,HSF2,SMAP1,ICA1,EID2B,SOWAHA,DISP2,KCNH2,A1BG-AS1,LSS,MEIS1,MEIS2,MGAT3,AFDN,MN1,ZNF680,HS6ST3,MYO7A,ZNF862,NBL1,NFYA,NNAT,PCSK5,PDCD2,PFKFB3,DUSP26,TMIE,FAM218A,PLCB2,PLCL1,SLC25A23,PRIMPOL,ING3,DRAM2,POU6F1,PPARA,NKAIN4,MAPK3,MAPK4,MAPK10,WBP1L,LAMA1,DEF8,ZIK1,CASTOR1,PTPRG,PTPRO,NKAIN1,PID1,RAD51D,NWD1,OXR1,RASGRF2,ZDHHC14,KCTD17,RIC8B,ARMC5,ELP2,SPIN3,MAP6D1,HSD11B1L,ATAT1,ZNF331,ZFP30,FAM102A,FERMT1,FNDC3A,NLGN1,SEC31A,NUBPL,SLC6A8,CCDC88A,SLC9A5,SLC12A2,ZNF334,BTBD7,SMARCD3,SNRPN,USP33,BDP1,SP2,ZSWIM8,IQSEC2,TSPYL2,SPART,ITPRID2,SSPO,DIP2A,PHLDB1,SYN2,SYT1,MTCL1,FAM208A,TBCEL,TCEA1,USP22,USP32P1,TNS2,HIF3A,ITGB3BP,SLC44A1,HEY1,ASXL3,RIMBP2,TRPS1,UBE2H,UBE3A,NPDC1,RICTOR,XRCC4,ZFP41,ZNF142,ZNF154,REEP1,UPF3A,SLC30A4,SEMA3B,KCNAB1,FIP1L1,TRIM16L,PDSS2,RGS7BP,MARCH8,FBXO36,SOCS4" MicroRNA hsa-miR-190:mirSVR_highEffct hsa-miR-190:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.54E-86 8.61E-83 1.50E-85 1.38E-84 216 1194 "KLHL32,PTCHD1,DPY19L2P4,ZNF608,KLHL13,TBC1D14,NME5,OSBPL6,HFM1,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APAF1,TNRC6C,CASK,NCOA1,NUMB,ADGRB3,LINC00847,SEC11C,DST,SYNJ1,SCAPER,CA8,HIP1R,CBLN1,CLGN,COPB2,RCBTB2,NDST3,NRXN3,PLAA,CNN3,ZFP28,CPS1,CLOCK,HAPLN1,ANKRD44,SEC24C,SOCS5,PDE4DIP,APPL1,RIMS2,BOC,RIPOR2,DCAF8,MYEF2,DMD,DMTF1,DRP2,PDCD6IP,DTNA,ECM2,EDIL3,EDNRA,RASGRP1,SEMA3D,PHF20L1,AASS,KCTD3,PLEKHA1,DCTN4,ENPP6,GPHN,NCALD,CEP85L,ETV1,SIRPB1,GMPR2,CLVS1,ABCA8,SH3YL1,TAOK3,CEP78,FKTN,FDFT1,SLC9B2,FGF14,FHL1,MEX3B,NBEA,UFM1,ATP6V1H,ATP2C1,ZNF605,STAU2,ZMAT1,MEGF10,RAPGEF6,IQGAP2,C15orf41,KIAA1841,PCDH17,PPARGC1A,MALT1,CRCP,TOX3,TNRC6A,DCLK2,PRUNE2,PCLO,AP4S1,PSIP1,GUCY1B1,HAS2,MIER3,ELOVL5,ZDHHC15,NEGR1,SMAP1,IRF8,IFI16,ZIC5,ITGAM,STXBP5,LIMS1,HECTD2,NCOA7,LYPLAL1,MATN2,MATN3,LRP1B,MID1,POC1B,ZNF680,BLOC1S2,MYO9A,NCAM2,NEK1,NF1,NRCAM,GPR137C,CNTN3,PAX6,ETFRF1,PCDH9,PDPK1,GNG2,OLA1,ZNF655,PLCL1,TRHDE,EPB41L4B,PPP2R2C,PPP2R5E,GRAMD1C,DIRAS2,BDNF-AS,PTN,TMEM260,SUSD4,ERI2,C12orf49,BAALC,ATP8B4,GLDN,RYR3,TRAPPC13,ATXN7,SCN7A,FNIP1,TNFRSF19,SEC14L1,TRA2B,FNDC3A,FHOD3,NLGN1,BTBD3,SEPHS1,SLC14A1,ZFP1,RCOR3,HECW1,MYCBP2,KDM4C,MCF2L2,RBM26,LARP4,NKAIN2,NXT2,RGL1,KLHL7,EXOC7,SATB2,TCF12,DOCK9,FAM200B,SIRT1,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,FAM124A,BEX4,RIMBP2,CSMD1,AMACR,STXBP4,PPIL6,TSC1,OSBP2,P2RY12,ZNF708,TRIM9,CELF4,ZSCAN26,ZFAND5,MAP3K12,ADAMTS9,CIAPIN1,NAV3,RNF170,FRMD6,GAN,SENP7" MicroRNA hsa-miR-486-5p:mirSVR_lowEffct hsa-miR-486-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-86 1.04E-82 1.80E-85 1.66E-84 230 1355 "CLK4,FMNL2,BRAP,DPY19L2P4,MTA3,AP2A2,ZNF608,MTUS1,HECW2,OSBPL8,SRPX,CDC42BPA,ARMC12,PHF12,PKP4,APC,FAM131A,CDK10,MADD,SPTBN4,MARK4,NCOA1,ATP2A2,BACH1,MPDZ,RGS9,BCL7A,SYNJ1,GYG2,PTBP2,CAST,CLDN10,KRIT1,USP2,CD86,SEPT7,LARGE1,MAGI1,CLGN,CHN2,CNTN1,AKAP6,COL9A3,MYRIP,NCOR2,RGS6,LRIG1,CSNK1G3,UBXN2A,CTH,RIMS2,BOC,HDAC9,ZNF337,IST1,PLPPR4,SV2B,GRIN3A,DYNC1I1,DMTF1,DTNA,DNAJB6,KRBA2,EDN3,MRO,TENM1,CERCAM,STARD3NL,C8orf37,DENND4A,EYA1,EZH1,ABCA8,FKTN,SEC24B,FER,POLK,SUCO,SMC2,UFM1,SARAF,DOT1L,HRASLS5,GAD1,ZNF274,ALDH1L1,AHDC1,BRD8,RNPS1,TNRC6A,KCNMB4,ZNF782,STON1,DIDO1,FAM19A2,RABL2A,IRAK3,ARHGAP36,HLF,HNF4G,ICA1,ZIC5,CYP27C1,SMAD1,ZFYVE27,MAP6,MARK3,AQP11,MEIS2,MIA2,MSR1,PTOV1,MYO7A,MYO9A,NCAM2,NELL2,NF1,NFE2L2,VWA2,NRCAM,OCRL,PCSK1,PDE4A,NALCN,SNX10,ZFYVE21,NLE1,SCHIP1,RETREG2,PPP2R2B,PPP2R5E,PPP3CA,HYDIN,PSD,PTK2,PTPRD,RAP1GDS1,OXR1,REV3L,ZNF532,CARF,ROBO1,ROBO2,RPE,SNX22,FBXW7,ATP8B4,HUNK,ATAT1,TRAPPC13,SALL1,SEC14L1,MRAS,HSPA4L,SGK1,ZFP30,ARX,KIF16B,CPEB3,FBXO11,NUBPL,WDR47,SEPHS1,SLC8A1,CCDC88A,SLC9A5,NAPB,LIMCH1,KDM3A,KDM4C,ZNF423,POGZ,SAMSN1,SEPT8,NUDT10,ANKRD12,TAF6,PDLIM2,ADGRL3,FBXW11,SMG6,SIN3B,ZEB1,SYNE1,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,TMPO,RIMBP2,CSMD1,KAT6B,RGMB,SSBP2,TTTY15,FAM155A,EIF4ENIF1,SLC35A4,UBTF,FLRT2,BCL2L13,TBC1D15,WIPF1,ZNF781,CFAP298,PCDH20,TRIM9,ELFN1,CELF4,ZNF213,EVI5,TUBA1A,SIGLEC10,PCBP4,UBE3B,HNRNPA3,PHTF2,FBXO36,ADAMTSL3,JMJD1C,KLHDC1,NETO1,SOCS4,CPNE4" MicroRNA hsa-miR-619:mirSVR_lowEffct hsa-miR-619:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.15E-86 1.20E-82 2.09E-85 1.92E-84 257 1683 "RALGAPA1,ABR,ACADM,TMCC3,USP31,SLC24A4,MTUS1,AK2,C1QTNF3,SPARCL1,SEMA6A,CARNS1,FAM135A,PITPNM2,CCDC146,SUGT1P4-STRA6LP-CCDC180,KCNAB2,NT5C3B,TNRC6C,PPFIA3,SFMBT2,ARRB1,TMEM108,ATP2B2,SLC2A11,ADAM23,ARHGEF7,CALB1,CALB2,VXN,CLDN10,USP6,MTMR7,C1orf52,DCLK1,LRRFIP1,ASIC3,RAB33A,TPP1,FBXO7,ABCG2,C4orf33,AKAP7,ARMC8,SLC4A8,COX4I1,SMARCAL1,CPS1,SEC31B,CS,ARHGEF10,OSBPL3,IPCEF1,VCAN,PPP1R16B,ARHGEF4,RUBCN,CYBB,EARS2,DGKG,DAPK1,DBI,AIF1L,DGCR5,ZBTB24,HEPH,SEC16A,DLX1,EXOG,USP3,DTNB,DNAJB6,KRBA2,E2F5,WDPCP,PHC2,TMTC1,CELSR3,FAM13A,SUGP2,EPB41,NCALD,MRPL37,MRPL10,EZH1,ZNF589,GTF2IRD2,FGF11,FGF12,FGF13,SCARA3,FLT1,C2orf88,WDR83,NSG1,MPP6,ABLIM2,TVP23A,GALNT15,GABRB3,GABRG1,FAM120B,GALC,ZNF274,TMEM8B,INPP5K,GATM,ALDH1L1,ADAM28,USP19,PPARGC1A,MSL3,GLUL,GNAO1,GPD1,GPR12,TMEM121B,STMN2,ADAMTS13,LINC01089,GSTM5,ADAMTS6,PADI2,HMGCR,ZNF491,CELF5,SMAP1,EID2B,FAM95B1,INPP5B,CDH20,KCNJ5,TTYH2,SYTL4,MAN2A2,ZFYVE27,MAT2A,ADAM11,CHIC1,MID1,POC1B,AFF1,XRRA1,LYRM9,MYO7A,ALDH1L2,CNOT4,NPTX1,PDCD2,PFKFB3,SERPINI1,NALCN,TRHDE,ING3,MBOAT7,EPB41L4B,POU6F1,RASGEF1B,MAPK4,EPDR1,WBP1L,PTCH1,BDNF-AS,MTMR10,PTPRE,C1orf109,CCDC40,NWD1,OXR1,RET,MORC4,UBR7,RGS12,CARF,PNMA8A,CCDC25,YY1AP1,SNX22,FBXW7,GLDN,SEC14L1,MRAS,KIF27,AMBRA1,CHD9,FHOD3,ANKRD6,BTBD3,KANSL3,SLC6A8,SLC6A11,SLC8A1,SLC12A2,SLC14A1,BTBD7,GKAP1,SMARCA4,SMARCD3,RCOR3,INAVA,SNCA,CMTR2,SNRPN,NMNAT2,MYCBP2,TEX2,CLSTN2,ITPRID2,NXT2,MPRIP,SEPT8,RGL1,PHLDB1,STX1A,MLST8,EXOC7,TAL1,TBCEL,DMXL2,TRIM2,CLASP1,CYB561A3,DICER1,ZFPM2,GALNT17,MTMR14,TMEM9,TLR4,TP53BP1,RASD2,WBP2,RGMB,PDSS1,TTTY15,TTC3,UBE2H,GORASP1,LINC00689,UGT8,PLEKHH2,VLDLR,LAT2,NDRG4,CELF4,TMEM237,FSTL5,PCBP1-AS1,DHX33,PRDM8,CIAPIN1,GAL3ST3,URM1,EPM2A,DOCK8,UBE3B,NLRP3,TIGD6" MicroRNA hsa-miR-1246:mirSVR_highEffct hsa-miR-1246:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-86 1.47E-82 2.55E-85 2.34E-84 222 1265 "KCNH8,METAP1D,XKR4,CCDC85A,ADD1,ADD2,AXIN2,BRAP,PWWP2A,ESYT2,INTS2,TAOK1,SEMA6A,CEP126,ARHGAP20,FAM135A,BEGAIN,AMPD3,ANK2,APC,BCAS1,CDC14B,NUMB,RASL11B,DYNLL1,ZNF583,RNF182,DPY19L3,MYOM1,RGS9,NRP2,ZNF599,CFLAR,PROM1,DST,ARHGEF7,GYG2,CA12,CALB1,THSD7A,CAMK2G,ISPD,LDB2,ARHGEF1,C1orf52,CDH2,CDO1,DLGAP1,SRSF11,CHN2,FAM19A5,QKI,FHL5,AKAP7,AKAP6,COL9A1,RTTN,ZFP28,CSNK1G3,SLITRK5,CCDC144A,LIN54,IP6K1,TMEM130,POM121,CHRDL1,DMD,DNAH9,DYNC1I1,DRP2,PDCD6IP,DUSP9,MAMLD1,EBF1,EDIL3,FSD1L,YAF2,FAM13A,MBNL2,GOLGA7,TENM1,GPHN,SLC43A2,F8,CLVS1,TMEM132C,SCML2,POLR1B,FGF14,IP6K2,ANKFY1,FYB1,GABRG2,ZNF234,CPLX2,TUBGCP4,ARFIP1,SESN1,MALT1,TXNL4A,LUZP2,FERMT2,GPR12,PCLO,PSIP1,RNFT2,ADAMTS6,FRMD3,MIER3,HLF,ELOVL5,SHISA6,SMAP1,IL6R,IL6ST,SLC35G1,KCNJ16,STXBP5,LAMP2,SYTL4,HECTD2,NCOA7,LSS,MARK1,MATN2,EFHB,MEF2C,MEIS1,MITF,ZNF680,MSR1,P2RY13,NF1,NTRK2,LOC100128398,CLDN11,PCDH9,GPR85,PIK3C2A,ZNF655,SH3KBP1,GRAMD1C,MASP1,SAMD9,VPS13C,WBP1L,PTCH1,PTPRB,EML5,ZNF615,QDPR,SLC25A48,RAP1GDS1,RDX,ZMAT4,REV3L,RIC8B,CARF,ROBO1,RPE,RTN1,FAM192A,CSRNP3,LRFN5,SHC4,FNDC3A,ANKRD6,WDR37,SLA,PREX2,DHX30,SEPHS1,CCDC88A,SLC12A2,TET1,ZFP1,ANKFN1,CLASP2,ZNF302,NKAIN2,ZSCAN29,KANK1,JMJD6,SYN2,ANKRD28,ADGRL3,ZEB1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,GPR161,R3HDM1,RGMB,METTL3,FAM155A,TBC1D15,GUSBP1,ZNF17,ZNF19,ZNF24,TRIM9,AGMO,LYPD6,FSTL5,ZNF195,SMARCAD1,KCNAB1,FAM47E,FAM13C,MARCH8,PHTF2,JMJD1C,NLRP3,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-216b:mirSVR_highEffct hsa-miR-216b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.68E-86 1.50E-82 2.59E-85 2.38E-84 237 1440 "CLK4,NCKAP5,SYS1,KLHL32,BRAP,PLEKHH1,PTCHD1,ZNF578,HFM1,TAOK1,C1QTNF3,SPOP,ZFAT,LRCH2,MAP4K3,PKP4,APBB2,DDO,ZFYVE28,CADPS,NUMB,RNF182,ALDH7A1,N4BP2L1,SEC11C,NRP2,BMP7,DST,NAE1,CA8,KALRN,VXN,CAST,RUNX1T1,C1orf52,LRRFIP1,CLGN,CFL2,B4GALT6,NDST3,C4orf33,QKI,AKAP6,COL4A5,SLC4A8,CPS1,FAM171B,CRY2,CLIP3,MROH8,LRIG1,ARHGEF10,SIPA1L1,PDE4DIP,DZIP3,RIMS2,FAM131B,CCDC144A,DOCK4,HDAC4,MATR3,MAML1,TMEM170A,PABPC5,ARMCX4,MYEF2,FBXL5,DDX46,WDR20,EXOG,HS3ST2,CPEB2,PDCD6IP,DNM1L,EBF1,EDIL3,EDNRA,EDNRB,HIPK3,CNNM1,MBNL2,PLEKHA1,PCOLCE2,CALCRL,CEP85L,ZNF549,CLVS1,FAM198B,ACSL4,FCGR1A,CHST15,ZSCAN30,FDFT1,FER,POLK,SUCO,ATP13A4,SPECC1,APOPT1,TVP23A,GABRA3,GAD1,TMEM8B,ALDH1L1,GCNT2,ARFIP1,WASHC2A,GPD2,PCLO,DIDO1,PSIP1,DDX19B,HLF,HMGCR,TCEAL6,ZNF546,ZIC5,IL6R,JAK2,CREG2,LAMP2,LIMS1,SMAD1,MBD1,MEF2C,SAMD5,MSR1,ZNF92,MYO7A,NF1,NFIX,NOVA1,NUCB2,IGSF11,CNTN3,PDE3A,PDE4D,FAM218A,FAM216A,PCDH18,EXOSC10,SCHIP1,PPARA,PPM1B,PRKACB,EPDR1,MAPK9,RELN,CNTLN,ANKHD1,PTPRB,PTPRN2,PTPRO,USP47,NWD1,OXR1,RASGRF2,RBBP6,RDX,RFX3,UBR7,SLC25A36,SETD5,CARF,ROBO2,CCDC25,RPE,TCP11L1,NCBP3,ZNF331,CCDC112,SAFB,TNFRSF19,CASC3,SCAF8,SGK1,FRMPD1,FBXO11,FNDC3A,PPP4R3A,SLC6A11,ARHGEF40,SLC14A1,ANKRD36,MBD5,TMCC1,TEX2,ZNF423,ZC3H13,SPART,LARP4,ZSCAN29,VPS13A,PLCB1,SYN2,TACC1,MTCL1,ZEB1,RPGRIP1L,PCDHGA11,SYNE1,PCDHB7,C18orf54,ITGB3BP,GALNT17,ARL10,TK2,ASXL3,TLR4,TMPO,CSMD1,NPL,AMACR,PPIL6,TSN,TTTY15,USP1,TOM1L2,CCDC14,WIPF1,CFAP298,PCDH20,KCNT2,TRIM9,ZSCAN26,ZNF189,EMSY,STOX2,ADAMTS9,FIP1L1,PLSCR4,PARP11,PDSS2,AMN1,KAT6A,PHTF2,JMJD1C" MicroRNA hsa-miR-140-5p:mirSVR_lowEffct hsa-miR-140-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-86 1.73E-82 2.99E-85 2.75E-84 242 1501 "SYS1,XKR4,NDRG3,ADCY6,BRAP,AP2A2,MTUS1,PCDH19,KCTD16,TAOK1,BBOX1,CCDC146,FAM131A,SHROOM2,CDC14B,RGS20,ZBTB10,DOCK11,BCHE,RGS9,BCL7A,BID,SYNJ1,FUBP1,JAZF1,RAB29,KALRN,LDB2,LARGE1,NUMBL,SRSF11,CHGB,LHX2,NRXN3,CNR1,AKAP6,LETMD1,CREM,NCOR1,SIPA1L1,VCAN,KIAA0040,ARHGEF4,USP6NL,ARHGAP32,HDAC4,EARS2,RASSF2,LONRF1,MATR3,KIAA0586,SCRN1,SPOCK2,PITPNC1,ZNF804A,KIAA0319,ZC3H11A,GUCD1,RHOBTB1,WDR20,RAB39B,DMD,SLC12A6,PDCD6IP,DTNA,EDN1,EDNRB,PHF20L1,EGFR,KCTD3,COPS4,CALCRL,LRRC17,EPHB1,GPHN,SRRM1,DENND4A,DNAJC27,KATNAL1,TUBB3,ST3GAL6,STRADA,KAT8,ZNF589,GORAB,FECH,GTF2IRD2,SUCO,MEX3B,SEMA4D,ATP13A4,EFCAB2,UFM1,CAMKK2,ATP2C1,OGA,ZNF234,DISC1,CYP46A1,SESN1,PPARGC1A,BRD8,GLI2,TOX3,GLUL,ZNF638,KCNMB4,ZNF782,GPD2,PRUNE2,PCLO,GRIK4,ADAMTS6,FAM222A,ELOVL5,EID2B,NKD1,RBPJ,LRRCC1,IL6R,GPR62,CREG2,CYP27C1,STMN1,LIMS1,LMO2,MAT2A,MATN2,CHIC1,SAMD5,ADAM22,HNRNPM,CCDC13,NFYA,NME4,NOVA1,NTRK2,PAX6,DPY19L2P2,PCSK1,GPR85,PFKFB4,PKM,SLC25A23,PURG,EXOSC10,RETREG2,RANBP3L,MAPK4,MASP1,WBP1L,QRICH1,ELOVL2,PTK2,PTN,PTPRE,FAM66C,FAT4,RAP1GDS1,ZNF493,OXR1,KHDRBS2,REV3L,ERI2,ZDHHC4,RGS3,SLC25A36,PBRM1,SUGCT,KLHDC8A,ROBO1,CCDC25,PCMTD2,CCDC102B,KCNIP1,SEMA6D,SCN7A,CASC3,FAM102A,FBXO11,WDR37,EPN2,SIRT2,CXXC4,INTS9,RCOR3,KIF13A,SOX11,SP4,PEG10,NFASC,POGZ,ITPRID2,ERBIN,ST5,CEP68,KANK1,SEPT3,KLHL7,VPS13A,TMEM150C,MMS19,CAMTA1,DNMBP,TCF4,ZFP90,CUX2,FAM189A1,PCDHB3,SIK3,DICER1,SLC44A1,TMPO,RIMBP2,C9orf85,ZNF346,TRIO,PDSS1,STXBP4,SSBP2,LINC00689,FLRT2,ZNF781,CLDND1,LYPD6,CELF4,POLR3H,ZNF189,DPYSL5,MAP3K12,CADM2,PRTFDC1,STOX2,KCNAB1,FZD3,CASC15,FAM219B,TIGD6,FRMD6,NETO1,RNF146,AP3B2" MicroRNA hsa-miR-1304:mirSVR_lowEffct hsa-miR-1304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-86 1.88E-82 3.23E-85 2.98E-84 252 1624 "SYS1,RNF157,ADD2,KCTD16,RTL9,HACE1,OSBPL1A,WDR35,CEP126,OGT,EP400,UPRT,ZBTB10,STX16,ATP2B2,ADGRB3,LINC00847,MIR9-3HG,DST,SYNJ1,GPC2,PTBP2,CAMK2A,HIP1R,SPAG9,ARHGEF1,LRRFIP1,ASIC3,NDST3,TPP1,FAM19A5,CNN3,CNR1,IQCK,PCYT1B,AHCTF1,CRY2,HINFP,ANKRD44,CS,MROH8,SNCAIP,OSBPL3,PDE4DIP,CST3,PLXNA4,UBXN2A,RUBCN,CYBB,ARHGAP32,LONRF1,TBC1D5,MAML1,SGSM2,TMCC2,DOCK2,DMTF1,RCAN1,DNAJB6,E2F6,EDNRA,OPTN,PHF20L1,TMEM132E,RASA4,GOLGA7,TNK2,C3orf18,COQ7,GPHN,STX2,NCALD,GMPR2,F5,CLVS1,FCGRT,FDFT1,FER,GTF2IRD2,FGF1,FGF13,FGFR1,HPCAL4,NOP56,SMC2,HVCN1,FAM49B,CGREF1,TPPP3,AP4B1,ZMAT1,GABRG2,DENND2A,ZNF274,ZNF559,GCNT2,CYP46A1,MMADHC,GHR,LYVE1,NTNG2,TTBK1,HPGDS,TDRKH,ADAMTS13,GRM2,PRDM5,KAT7,FAM222A,IRAK3,BACH2,ZDHHC15,LRRC75A,SMAP1,C2orf72,NKD1,ZNF678,PAXBP1,ZFYVE27,MAT2A,AQP11,KITLG,MITF,AFF1,AFDN,GIT1,DBNL,BLOC1S2,ADAM22,ZNF92,MXI1,MYCN,P2RY13,NDP,NEK1,NF1,DNHD1,NRCAM,OCRL,OPRL1,PCDH9,PCSK5,CDK18,PDE4A,PDE4D,GPR85,GNG2,PFKFB3,PIK3R1,FAM218A,PURG,MAPKAP1,ING3,RETREG2,POU6F1,PPARA,MAPK4,DIRAS2,SAMD9,WBP1L,CNTLN,TTC13,QDPR,TMEM255A,NWD1,OXR1,KHDRBS2,FIGN,RGS4,CARF,NEK11,RPL15,LRRK2,PTGR2,ABCA11P,TRAPPC13,SEMA6D,ATXN7,SCP2,FNIP1,TNFRSF19,GALNT10,SUPT20H,TRA2B,ZFP30,R3HDM2,SEC31A,SLA,SLC11A1,SLC12A2,SLC12A4,CPEB4,DMRTC1,MYH15,ANKRD36,MBD5,FAM126B,MYCBP2,SPTAN1,IQSEC2,TSPYL2,ATP10B,NXT2,DIP2A,NSFL1C,NUDT10,CAMTA1,MCF2L,TAL1,DMXL2,SYNE1,DICER1,DICER1-AS1,ZFPM2,ZMAT3,SLC44A1,ARL10,ICAM5,ERCC6L2,KAT6B,SMUG1,STXBP4,TRPS1,PPIL6,TSN,ANKRD20A2,SSBP2,UCHL1,PLEKHH2,MGAT5B,TBC1D15,CLDND1,RICTOR,GUSBP1,XPO1,ZNF24,MKRN3,LYPD6,POLR3H,ZNF184,EML6,DPYSL5,SPIRE1,ZNF225,MFF,STOX2,URM1,FIP1L1,EPM2A,UBE3B,GJC2,IFT88" MicroRNA hsa-miR-1248:mirSVR_highEffct hsa-miR-1248:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.62E-86 2.03E-82 3.48E-85 3.21E-84 240 1478 "RALGAPA1,NCKAP5,NDRG2,RNF157,ADD2,PTCHD1,CC2D2A,AK2,ADGRF5,FAM135A,AMPD3,AMPH,DPP10,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,USP37,CCAR2,STX16,ADAM23,RGS9,SYNJ2,GPC2,CA8,DDR1,KALRN,PTBP2,VXN,RUNX1T1,CBR1,CCNT1,MTMR7,LRBA,MS4A7,B4GALT6,NDST3,PLAA,CLCN3,VAX2,IQCK,WHRN,AHCTF1,SLC35F1,SEC31B,ANKRD44,SNCAIP,RGS6,CSNK1G3,GALNT9,PDE4DIP,CNTNAP2,PLXNA4,CCDC144A,CYBB,DOCK4,HDAC9,MYADM,GAPVD1,CENPL,MATR3,BRINP1,ALKBH8,SV2B,DLX1,DMD,CPEB2,DMTF1,PDCD6IP,DTNA,ABCC5,FCF1,FSD1L,PHF20L1,PLEKHA1,DCTN4,RCAN2,SRRM1,IGSF6,EYA1,F5,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CEP78,FGF1,FGF12,FGF13,FGFR1,POLK,SYNCRIP,NOP56,NELFCD,C2orf88,AKAP3,SMC2,UFM1,CAMKK2,PRELID3A,STAU2,ZMAT1,GALNT15,GABRG2,TRAF3IP2,GAD1,C15orf41,DISC1,GCNT2,SULT1C4,WASHC2A,CYP46A1,ADAM28,PCDH17,PPARGC1A,POLL,TDRKH,STON1,PCLO,CLASRP,RNF165,AP4S1,MAP4K5,ZHX1,ARHGAP36,HNF4G,NEGR1,IRF8,IL12A,INPP5B,KCND1,CREG2,KTN1,LAMP2,SYTL4,HECTD2,PIK3AP1,MMP16,LAYN,ZNF862,NF1,NINJ2,CNOT4,NOVA1,NRCAM,NUCB2,OGG1,OXTR,PRTG,PDE1B,GPR85,TMIE,XRN1,FAM216A,POLG,KANSL1,SNRK,CNTLN,BDNF-AS,TMEM260,ZSCAN32,ENOX1,OXR1,RASGRF2,RDX,ERI2,RFX2,RFX3,RIC8B,CCDC102B,NEK11,RPL15,FBXW7,SPIN3,CCDC112,GALNT10,SH3GL3,ASAP3,CPEB3,FHOD3,NLGN1,SLA,SLC6A11,SIRT2,SLC14A1,ATF7IP,TET1,DMRTC1,SNCA,BDP1,SP4,MYCBP2,KDM4C,ZC3H13,CDK19,ATP10B,TROVE2,SSTR2,TTBK2,SULF2,VPS13A,NUDT10,C12orf76,CAMTA1,TAF9,EXOC7,SZT2,DOCK9,PCDHB10,GPRIN3,FRYL,FAM200B,ITGB3BP,SLC44A1,TIAM1,MTMR14,BHLHB9,ERCC6L2,SYNPO2,TRPS1,ANKRD20A2,SGK3,ZNF45,AGMO,LYPD6,ZNF184,RNF103,ADAMTS9,NAV3,PPP1R3F,FIP1L1,PCBP4,WNK3,PDSS2,FAM13C,UBE3B,HNRNPA3,CASC15,JMJD1C,TRAM2-AS1" MicroRNA hsa-miR-219-1-3p:mirSVR_lowEffct hsa-miR-219-1-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.64E-86 2.04E-82 3.49E-85 3.22E-84 257 1687 "RALGAPA1,ABR,CLK4,AS3MT,SYS1,GALNT13,ADD1,PWWP2A,KLHL13,WDR35,CC2D2A,ALCAM,PCDH10,BBOX1,FAM135A,AMPD3,AMPH,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,LGR5,MADD,IGDCC4,ARHGDIA,LINC00173,CHID1,SLC4A4,ATP2A2,ATP2B2,N4BP2L1,DPY19L3,ATP6V0A1,KIF1A,RGS11,SCAPER,CACNA1A,CALB1,PTBP2,VXN,HIP1R,CCNH,DGKI,LRBA,CDH2,NRXN3,CLTC,QKI,MAP4K4,CNN3,CNR1,PCYT1B,ARMC8,LETMD1,CNRIP1,CRMP1,GDA,SNCAIP,CSF1R,PDE4DIP,PHACTR3,CST3,ERC2,PLCXD3,RUBCN,SEC14L5,TM9SF4,TBC1D5,TMEM170A,BRINP1,DNAL1,ARMCX2,SV2B,SEC16A,DLX1,GRIN3A,DMD,HS3ST2,RCAN1,ECM2,TOM1,DNAJB6,E2F6,SNX29,TMTC1,OPTN,YAF2,CELSR3,KMT5B,RASA4,MRNIP,TMEM35A,CALCRL,TUBD1,EPHB1,SPEG,APC2,ADGRV1,TBC1D16,ZNF589,FER,GTF2IRD2,ATP13A4,C2orf88,PDLIM5,TRIM16,CELF1,CSPG5,STAU2,CHL1,SIGLEC8,MTHFD2,KIAA1841,ALDH1L1,ZNF276,GLI2,MSL3,GNAO1,FERMT2,GPD2,TDRKH,GRIA2,GRM2,RNF165,ZBTB49,RNFT2,PADI2,FRMD3,LRRC25,ZNF678,INSM1,NME9,STXBP5,LMO2,ASPRV1,SMAD1,MAP4,MBP,ADAM11,TM6SF1,LRP1B,AFF1,ADAM22,PTOV1,NRBP2,N6AMT1,TAGLN3,SFR1,NEK1,NFYA,NTRK2,NUCB2,ZNF713,P2RX7,GLIPR1L2,PDE4A,ENPP2,PFKFB3,TMIE,CCSER2,FAM216A,PMP22,PPARA,PCDHB17P,PPP2R5E,RASGEF1B,PRKACB,MASP1,VPS13C,LAMA1,CNTLN,BDNF-AS,ELOVL2,TMEM260,PTPRG,PID1,FAT4,NWD1,RASGRF1,RASGRF2,GTDC1,EXD2,GSTCD,CCDC102B,EPHA10,RPL15,ARMH4,RPS20,ZNF568,STX1B,ZNF331,DGLUCY,CSRNP3,ATXN2,SCP2,ZFP2,MRAS,ASAP3,HKDC1,NLGN1,WDR47,SEPHS1,SLC11A1,SLC14A1,ATF7IP,CPEB4,EPC1,INTS9,SNRPN,TMCC1,RBM34,TRERF1,KDM3A,NMNAT2,PEG10,SPTAN1,ERBIN,ELOVL4,DIP2A,NECAB1,SYNE2,ARHGEF9,TACR1,EXOC7,WSCD1,DMXL2,SATB2,ZFP90,TRIM2,SYNE1,DOCK9,PUM2,TNS2,FRYL,HIF3A,SIRT1,SLC44A1,THRA,MTMR14,NPL,C9orf85,ZNF346,SYNPO2,TRIO,PDSS1,STXBP4,UBE3A,P2RY12,CLDND1,KCNT2,ZNF138,REEP1,FTSJ1,DNALI1,WNK3,DNAH10,CASC15,MSRB3" MicroRNA hsa-miR-548s:mirSVR_lowEffct hsa-miR-548s:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-86 2.18E-82 3.74E-85 3.44E-84 261 1738 "DGCR6,ABR,SYS1,ADCY6,TMCC3,RNF150,PTCHD1,KLHL13,OSBPL1A,SMIM17,CEP126,FAM135A,SYT13,FGD2,PHYHD1,VAT1L,AQP6,CHID1,SLC4A4,ATP1B3,STX16,SLC2A11,ATP6V1G2,BBS2,DNAJC27-AS1,KSR1,SCAPER,AP1M1,LURAP1,KALRN,PRC1,PLEKHB1,CPNE6,CLTC,SRP14-AS1,ARHGEF6,CNTN1,PCYT1B,LETMD1,ABI3BP,ZFP28,IGDCC3,SLC35F1,SH2B1,HINFP,CS,CSF1,SUSD5,IPCEF1,RASGEF1C,GREB1,KATNAL2,GAPVD1,EARS2,ZNF337,RASSF2,TBC1D5,AIF1L,GIT2,ARMCX4,FBXL5,KIAA0319,GUCD1,SGSM2,DLX1,RAB39B,CASP8AP2,DPP6,ARRDC4,DNAJB6,ABCC5,DNM1L,AASDH,SNX29,EDNRB,RASGRP1,TMTC1,SUGP2,MRO,MBNL2,AASS,ENPP6,NCALD,PIPOX,VPS26C,ADGRV1,ZNF461,FCGR3A,GTF2IRD2,OLFM1,FGFR1,FOXF2,SYNCRIP,ANKFY1,PSD2,TMEM107,TRIM16,ERGIC3,CGREF1,ST6GALNAC3,MSANTD4,FYB1,GABRA3,GABRB3,GABRG1,GALC,RAPGEF6,ZNF559,CPLX2,KIAA1841,ALDH1L1,GCNT2,PPARGC1A,CRCP,ZNF638,LNX1,GPD2,PCLO,ATE1,PRDM5,GUCY1A1,TNFAIP8L3,MIER3,SYNPO,ZDHHC15,HSF2,SOWAHA,IGF1,ZIC5,SCIN,ITPKB,SLC35G1,KCNB1,KCNN1,GATD1,KTN1,STMN1,PAXBP1,NCOA7,MAP4,MBP,TM6SF1,SRSF12,MID1,PPM1L,AFDN,MSR1,NF1,NPR2,NTRK2,IGSF11,OGG1,TREM2,PCDH9,TMEM38A,PLCB2,PLIN1,FXYD1,PLXNB1,PURG,SCHIP1,ING3,DCHS2,QRICH1,PIGG,PTPRD,CASTOR1,PTPRG,ACSS3,ZNF793,OXR1,RASGRF2,MSANTD2,TRIM68,RGS4,GSTCD,ROBO1,NEK11,RPL15,FBXW7,MCMBP,STK32B,RPS20,HSD11B1L,ZNF331,CCDC112,FAM192A,SCP2,RASA3,SCAF8,ZFP30,SH3BP2,FAM102A,DZIP1,DHX30,PKNOX2,SLC14A1,ELMO2,CDK5RAP2,SNCA,TMCC1,DOP1A,IZUMO4,ERC1,DDN,POGZ,ITPRID2,SSTR2,SULF2,KLHL7,SYNE2,NUDT10,TACC1,TACR1,TBCEL,KIAA0930,TPCN2,SYNE1,DOCK9,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,AP4E1,ARL10,TIMP4,ASXL3,BHLHB9,ERCC6L2,TPM2,C9orf85,ELP5,TRIO,TRPS1,HIRA,FAM155A,UGT8,PLPPR2,CCDC136,VLDLR,CLDND1,ZNF540,TMEM237,PCBP1-AS1,GDPD5,LINC02210,SIGLEC10,TRIM16L,WNK3,EPM2A,DNAH10,UBE3B,TRAM2-AS1,RNF170,FRMD6,IFT88" MicroRNA hsa-miR-141*:mirSVR_highEffct hsa-miR-141*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.97E-86 2.22E-82 3.80E-85 3.50E-84 225 1302 "RALGAPA1,KCNH8,NCKAP5,OLMALINC,CC2D2A,SPOP,ALCAM,FAM135A,AMPD3,AMPH,OGT,UPRT,PPP4R4,MADD,ZFYVE28,BBS2,PROM1,DST,ARHGEF7,FUBP1,BTK,PTBP2,CAST,ZNF501,USP6,C1orf52,SEPT7,ZMYM4,CDO1,CDR1,LHX2,ABCG2,QKI,MAP4K4,CNR1,IQCK,SLC4A8,AHCTF1,C2CD2,CREM,RBM39,CRMP1,HAPLN1,ABCG1,ARHGEF10,SLITRK5,PHF14,CTH,ZSCAN23,TCAF1,ZFYVE16,KCTD8,TMEM170A,BRINP1,DBI,GIT2,ALKBH8,RHOBTB1,USP3,DMTF1,PDCD6IP,RCAN1,ANKRD46,PHF20L1,EGFR,GOLGA7,KCTD3,C8orf37,MRVI1,NRN1,DLC1,CEP78,CHST15,FDFT1,POLK,SEMA4D,NOP56,SMC2,UFM1,PDLIM5,ST6GALNAC3,HRASLS5,GALC,DISC1,NEU3,ADAM28,GGT7,GHR,LYVE1,SPIN1,TNRC6A,ZNF638,LUZP2,ADGRA3,GPD2,GPR37,FRMD3,DDX19B,ATXN2L,SYNPO,HMGCR,SMAP1,IRF8,SCIN,IL6R,IL6ST,ZNF678,KCNH2,KCNN2,CREG2,STMN1,LIG4,MARK1,MATN2,MBD1,LRP1B,KCTD6,MSR1,BEX5,SFR1,NEK1,NF1,NOVA1,TREM2,ETFRF1,GPR85,ZNF655,FAM218A,SNX10,RETREG1,PLIN1,MTRF1L,PSAT1,PPP2R5E,PRKAB2,MAPK4,EPDR1,GRAMD1C,MASP1,KLK6,CNNM2,NDUFS7,VPS13C,TMEM260,PTX3,TMEM255A,SH3TC2,C1orf54,ZCWPW1,OXR1,RASGRF2,TRIM68,MORC4,RGS12,CCDC82,ROBO2,ELP2,NEK11,BAALC,TCP11L1,RPS6KA2,PTGR2,KCNIP1,ATXN2,SGK1,SHMT2,CHD9,WDR47,BTBD7,ATF7IP,SLC22A4,RCOR3,ANKRD36,LIMCH1,MBD5,CMTR2,BDP1,GLT8D1,ZBTB43,SAMSN1,ERBIN,ZSCAN29,TTBK2,VPS13A,PLCB1,SYN2,SYT1,DNMBP,TAL1,RPGRIP1L,SYNE1,FRYL,PMS2CL,C18orf54,ITGB3BP,AKTIP,TMEM9,CDK20,TSC1,CLHC1,RPL7L1,UBE2H,UGT8,PLEKHH2,ZNF781,XRCC4,MICU3,KCNT2,ZNF540,MKRN3,POLR3H,ZSCAN26,ZNF189,MEIS3,TMEM178A,DNAH10,FAM13C,CASC15,ADAMTSL3,KLHDC1,NETO2,NETO1,DPF3,GAN,SENP7" MicroRNA hsa-miR-4323:mirSVR_lowEffct hsa-miR-4323:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.54E-86 3.10E-82 5.29E-85 4.87E-84 237 1445 "RALGAPA1,KCNH8,ACHE,NCKAP5,SYS1,NDRG2,TMEM132B,GALNT16,ADCY6,TMCC3,ADD2,AMPD3,MAP4K3,PPFIA3,PPP4R4,SPTBN4,ARNTL,MARK4,PCDHGB4,NUMB,CCAR2,N4BP2L1,RIPK1,SLC25A14,HIP1R,CBR1,ENTPD6,L3MBTL4,CACNA2D2,ASIC3,CNOT8,TAOK2,EPS15L1,DGCR9,ABCG2,TMEM184B,SRP14-AS1,HOMER3,CNR1,SLC4A8,ABCG1,CS,RGS6,DCAF8,LONRF1,IST1,DGKB,SPOCK2,IP6K1,DBI,GIT2,DNAL1,ZBTB24,B3GAT3,WDR20,DNM1,USP3,DMTF1,DPP6,ACOT8,ARRDC4,TOM1,DUSP9,AASDH,EDN1,FAM13A,RASA4,EIF4G1,EPB41,ERBB2,PIPOX,DNAJC27,EZH1,ZNF461,TBC1D16,PTK2B,FGF1,TMEM164,NOP56,TMEM107,BRSK1,ABLIM2,TVP23A,SDCBP2,GABBR1,ZNF234,ZNF559,DISC1,SULT1C4,GPR162,GFER,TTBK1,ZNF638,GPD1,GPD2,CCDC184,MCHR1,C1QL4,PLCD4,GRM2,PRDM5,RABL2A,ATOH8,PADI2,HMGCL,CELF5,IRF8,C2orf72,SOWAHA,INPP5B,KCNH2,KIFC3,STXBP5,STMN1,NCOA7,ZFYVE27,MAP4,MAP6,MBNL1,AFF1,MOV10,MSI1,PTOV1,MYO9A,RTL5,ZNF862,NEK1,NELL2,NOVA2,NTRK2,OCRL,P2RX7,P2RY1,CNTN3,PCDHGC3,PFKFB2,ZNF655,ZFYVE21,EPB41L4B,POLR2F,RASGEF1B,MAPK9,GDPD1,PSD,DEF8,PIGG,PTN,ACSM5,RIPOR1,CEP97,TMEM255A,CCDC40,RAD51D,KHDRBS2,UBR7,MRPS18A,C12orf49,KLHDC8A,ARMC5,CARF,CCDC25,YY1AP1,SPIN3,STK32B,MEG3,SAFB,ATXN2,SCN2B,GALNT10,RASA3,FAM102A,PPM1E,FUZ,NUBPL,FAM81A,DHX30,DMRTC1,SMARCD3,MYO16,NFASC,RGL1,PHLDB1,STX1A,SEPT3,SYP,SLC37A2,DNMBP,ADGRL3,TCF4,SIN3B,DMXL2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,GPR161,ARL10,TIAM1,FAM124A,BEX4,TNS1,NR2C2,ZNF346,SMUG1,TRO,NUTM2A,RUSC1,BCL2L13,ZBTB14,EML6,MAP3K12,ADAMTS9,HPS4,KCNAB1,WNK2,PARP11,GJC2,FAM219B" MicroRNA hsa-miR-9-5p:TargetScan hsa-miR-9-5p TargetScan 7.25E-86 4.06E-82 6.91E-85 6.36E-84 197 997 "ASIC1,GALNT16,ADCY5,ADCY6,ADD2,RNF150,ESYT2,PTCHD1,HECW2,AK2,ALCAM,PCDH10,GPRASP2,PITPNM2,ANK2,PKP4,PARG,ARHGDIA,CDK13,CCAR2,INSYN2B,HCN2,KSR1,DST,MTMR2,MYRF,CALB2,PTBP2,RUNX1T1,CCNT1,CBFA2T2,LRBA,ARHGEF2,EVI5L,L3MBTL4,DLGAP2,FOXN3,FAM19A5,QKI,HECTD1,FHL5,CNTFR,COL9A1,BAG4,NSL1,CLOCK,C2CD2,HAPLN1,NCOR2,AATK,OSBPL3,PLXNA4,FAM169A,PITPNM3,GREB1,RIMS2,CCDC144A,ARHGAP24,DGKB,PITPNC1,ARMCX2,DCTN1,JAKMIP2,MFAP3L,RHOBTB1,SACS,FAM107B,CPEB2,DRP2,PDCD6IP,EBF1,HIPK3,CNNM1,FRY,FSD1L,OPTN,PHF20L1,EGR3,EIF5,PLEKHA1,RCAN2,ENPP6,CHST15,FGF12,FGF14,AMOTL2,FOXO3,DCTN2,C2orf88,CAMKK2,DOT1L,GAD1,B4GALNT1,MTHFD2,AHDC1,PCDH17,LYVE1,KIAA1958,PTPRT,ATOH8,HAS2,MIER3,ACOT7,AGFG1,ICA1,IGF1,IL6R,IL6ST,KCNB1,KCNK3,KCNN3,KCNQ3,CREG2,LIFR,NCOA7,MBNL1,ADAM11,MEF2C,KITLG,AFF1,MMP16,DBNL,MYO9A,NEK1,NME4,NPTX1,GPR137C,CNTN3,PCDH9,PCSK5,CDK18,PDE3A,PIK3C2A,CCSER2,PPARA,MAPK4,CNNM2,PIGG,PTCH1,EML5,PTPRG,MARCH1,RASGRF2,PRRT2,RFX3,PBRM1,ALG9,RORB,MCMBP,RPS6KA2,HUNK,RXRA,SCN2B,FNIP1,COPZ1,KIF21A,ARX,CPEB3,AMBRA1,FAM81A,CCDC88A,BTBD7,ATF7IP,CPEB4,OGDHL,MBD5,KIF13A,CMTR2,FAM126B,NFASC,ELOVL4,PHLDB1,ANKRD12,FAM208A,KIAA0930,DOCK9,FRYL,DICER1,AP4E1,CBX5,ASXL3,NR2E1,RASD2,DOK6,RUNDC3B,EVI5,PRDM10,ADAMTS9,ITM2C,FAM13C,PHTF2,RSPRY1,NHSL1,FXR1,FRMD6,DPF3,RNF146" MicroRNA hsa-miR-502-3p:mirSVR_lowEffct hsa-miR-502-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.38E-86 4.13E-82 7.03E-85 6.47E-84 225 1306 "ASPHD1,NCKAP5,XKR4,FMNL2,RNF157,MTUS1,KLHL13,TXNDC16,TAOK1,ALCAM,PCDH10,AMPD2,AMT,DPP10,SEMA4G,ZBTB10,ATP2A2,DPY19L3,TTLL9,BCHE,C5,MYRF,CACNA1B,MTMR7,CD38,DCLK1,DLGAP1,PPT2,CLTC,QKI,TMEM184B,MAP4K4,LETMD1,AKAP5,TOGARAM2,FAM171B,SEC31B,SEC24C,LRIG1,ARHGEF10,OSBPL3,SIPA1L1,CST3,PLXNA4,FAM169A,KIAA0040,ERC2,RIMS2,SEC14L5,KIAA0408,HDAC9,GAPVD1,LONRF1,KCTD8,DGKB,GIT2,KLHL3,DMD,DYNC1I1,DMTF1,DTNA,ABCC5,HIPK3,SEMA3D,EGFR,LRRC17,CEP85L,ZNF549,ADGRV1,FAM198B,MED12L,FGF13,FGFR1,FLYWCH1,UFM1,TPK1,ATP2C1,GABRG2,GAD1,B4GALNT1,C15orf41,ALDH1L1,GCNT2,GGTA1P,PPARGC1A,TCERG1,RAB30,GPR12,DIDO1,PLPP7,SERP2,ATE1,FAM19A2,RNFT2,GABARAPL2,EID2B,KCNK3,KIF2A,LAMA2,ZFYVE27,MARK1,LYPLAL1,MBNL1,LRP1B,MID1,COL28A1,N6AMT1,MXI1,MYO7A,ZNF862,TCEAL5,NEFH,NELL2,NFE2L2,ALDH1L2,SMIM11A,TBC1D25,OCRL,P2RY1,PAX6,PCSK5,PDE4D,PFKFB2,PFKFB3,DUSP26,ZNF655,XRN1,MTRF1L,ING3,PPM1B,GDPD1,SNRK,CNTLN,MTMR10,TMEM260,PTPRO,ZNF844,TMEM255A,CCDC40,ZNF793,REV3L,RGS3,SLC25A36,RIC8B,CYB561D1,RORB,ELP2,RPE,FBXW7,ADAL,MAP6D1,KCNIP3,RTN1,AP1AR,RMI1,SCN2B,SCP2,GALNT10,SUPT20H,SYBU,NLGN1,FAM81A,PPP4R3A,ZNF430,SLC9A5,ATF7IP,TET1,SMARCC2,SMARCD3,SNAP25,SNRPN,FAM126B,PDZD2,NFASC,ATP10B,TROVE2,SSTR1,LARP4,NXT2,ELOVL4,CEP68,DIP2A,KANK1,NECAB1,ZC3H4,SYNE2,VPS13A,ANKRD28,ANKRD12,MTCL1,CAMTA1,DOCK9,TEK,C18orf54,AP4E1,ACTR6,ERCC6L2,CSMD1,NPL,DOK6,AMACR,HSPBP1,PRR18,SLC35A4,MGAT5B,RICTOR,XPO1,PCDH20,ZIC1,ZNF711,ZNF708,ZNF24,TMEM198,ZFAND5,CADM2,PRDM8,ADAMTS9,TMEM178A,HRASLS,DOCK8,PHTF2,ADAMTSL3,NHSL1,IFT88,ST8SIA2" MicroRNA hsa-miR-103-2*:mirSVR_highEffct hsa-miR-103-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.80E-86 5.48E-82 9.31E-85 8.57E-84 236 1437 "KCNH8,KLHL32,TMCC3,PLEKHH1,KIAA1211,AP2A2,WDR35,CC2D2A,ALCAM,ABCD2,PCDH10,UNC79,ANK2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,LGR5,ARNTL,RGS20,MARK4,TMEM108,ADAM23,BACH1,ADGRB3,CFLAR,SYNJ2,NAE1,CACNA1G,CA4,CACNB4,VXN,ISPD,RUNX1T1,CERS5,CCNT1,LRBA,ARHGEF2,LOC730101,MAGI1,CLGN,NOG,CHGB,NDST3,NGEF,ABCG2,AKAP7,FAM149A,SLC4A8,BAG4,MYRIP,CLOCK,CREM,SH2B1,AKAP12,HAPLN1,GDA,OSBPL3,VAC14-AS1,PDE4DIP,DZIP3,UBXN2A,PHF14,GREB1,RIMS2,CYBB,BOC,DGKB,ARMCX4,ZBTB24,HEPH,DDX46,SPOCK3,WDR20,DLX1,EXOG,DTNA,ECM2,ABCC5,GOLT1B,HIPK3,RASGRP1,FSD1L,MBNL2,KMT5B,TENM1,TMEM35A,EPB41,LRRC17,CDKL3,F5,SCML2,CEP78,FER,FGF1,OLFM1,FGFR3,FHL1,NBEA,SMC2,HVCN1,ZNF605,SARAF,AP4B1,ABLIM2,MEGF10,ERAP1,SESN1,GHR,COPS8,MSL3,ZNF638,GNAL,FERMT2,GPD2,GRIA2,PLCD4,ZHX1,AGBL5,ZNF491,USP51,NEGR1,SHISA6,SMAP1,SCIN,IL6ST,KIFC3,KTN1,NCOA7,LYPLAL1,TM6SF1,MEF2C,MID1,MITF,AFDN,XRRA1,GIT1,LAYN,MYO7A,RTL5,NCAM2,NELL2,NF1,SMIM11A,NUCB2,OGG1,OXTR,GPR137C,PCSK1,PDE3A,GPR85,GNG2,PFKFB3,TMIE,SNX10,RETREG1,ANKRD16,SCHIP1,DRAM2,KANSL1,CNNM2,PTPRE,RAP1GDS1,ZNF493,OXR1,ZDHHC14,PBRM1,ZFHX4,LGI2,CARF,ROBO1,ROBO2,NEK11,ARMH4,TCP11L1,ATAT1,RYR3,TRAPPC13,SEMA6D,SGK1,SH3GL3,ARX,CPEB3,SYBU,PPP4R3A,SLC8A1,CCDC88A,SLC12A2,ATF7IP,RCOR3,ANKRD36,SNRPN,PDZD2,DOK5,TSPYL2,SPART,CLASP2,LARP4,NKAIN2,RGL1,SUPT5H,PLCB1,TBCEL,RPGRIP1L,PCDHB7,DICER1,SIRT1,SLC44A1,ERCC6L2,C9orf85,SYNPO2,AMACR,SSBP2,ZKSCAN5,USP1,ZNF709,BCL2L13,P2RY12,ZNF711,MICU3,AGMO,SMARCAD1,UPF3A,PRTFDC1,DNALI1,VPS35L,FIP1L1,FAM13C,MARCH8,CASC15,TRAM2-AS1,KLHDC1,FXR1,FRMD6,GAN,FAM198A" MicroRNA hsa-miR-10a:mirSVR_lowEffct hsa-miR-10a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-85 5.74E-82 9.72E-85 8.95E-84 245 1546 "FMNL2,TMEM132B,ZNF608,MTUS1,PCDH19,KCTD16,TAOK1,SEMA6A,CEP126,AMPD2,FGD2,LCORL,CDK10,SFMBT2,SPTBN4,PLA2G4C,CDK13,DYNLL1,CHID1,SLC4A4,DPY19L3,ADAM23,BMPR1B,NAE1,LURAP1,CAMK2B,CAMK2G,SPAG9,ZNF501,METTL6,LRRFIP1,ZNF445,NDST3,FBXO7,ABCG2,MAP4K4,CNGA3,ARMC8,SUMF2,LETMD1,TOGARAM2,HINFP,NCOR1,GDA,ABCG1,CS,LRIG1,CSNK1G3,SOCS5,VAC14-AS1,PDE4DIP,PPP1R16B,UBXN2A,HDAC4,DAPK1,ARMCX4,RUSC2,POM121,WDR20,GRIN3A,NYAP1,ECM2,TOM1,DNAJB6,E2F5,SNX29,FAM13A,MBNL2,IRAK4,COPS4,MRNIP,C3orf18,DCTN4,COQ7,LRRC17,RABEPK,DENND4A,ZNF549,VPS26C,DLC1,PPP1R1B,GORAB,POLR1B,TMEM164,PRKAG2,SEMA4D,FLT1,ANKFY1,JKAMP,ZNF605,ERGIC3,CELF1,CGREF1,STAU2,CHL1,GALNT15,GABRG1,RAPGEF6,ZNF559,ALDH1L1,WASHC2A,MMADHC,LYVE1,CRCP,MSL3,KCNMB4,TMEM121B,GRIK4,GRM8,LINC01089,BTN2A1,BACH2,GABARAPL2,HNF4G,ZNF491,NEGR1,FAM95B1,IDH3B,GPR62,KCNN2,STXBP5,HECTD2,NCOA7,LSS,CLEC18A,ZFYVE27,MAP2,MAP4,MBP,MGAT3,BLOC1S2,MSR1,MXI1,MYO6,MYO7A,NTRK2,NUCB2,CLDN11,PDE4A,ZFYVE21,NLE1,SMIM7,SEPT4,TATDN3,GRAMD1C,PSD,BDNF-AS,PTH1R,TMEM260,PTPRO,ZSCAN2,TTC13,CCDC40,ZNF493,DPF2,GTDC1,UBR7,KCTD17,MRPS18A,ZNF532,CARF,KIRREL1,RPL15,ARMH4,MCMBP,ZNF568,ZNF331,ATXN7,TNFRSF19,SUPT20H,COPZ1,SGK1,ASAP3,FUZ,FBXO11,FNDC3A,KANSL3,SEPHS1,RADIL,SLC11A1,BTBD7,CPEB4,MAPKBP1,MBD5,SNRPN,TMCC1,FAM126B,RBM34,SOX3,BDP1,KDM4C,ERC1,UNC5B,TSPYL2,SPART,LHPP,LARP4,ERBIN,SEPT8,RGL1,KANK1,SEPT3,VPS13A,SYN2,ANKRD28,PJA1,FAM208A,TBCEL,IQCE,NEU4,DMXL2,SATB2,TNS2,DICER1-AS1,AP4E1,MTMR14,TLR4,TMPO,CSMD1,KAT6B,C9orf85,STXBP4,PPIL6,TSC1,OSBP2,FLRT2,ZNF709,VIPR2,WIPF1,CLDND1,LYPD6,CELF4,EML6,SPIRE1,ZFAND5,EMSY,LINC02210,TUBA1A,HPS4,FIP1L1,TRIM16L,PLSCR4,UBE3B,ADAMTSL3,SENP7" MicroRNA hsa-miR-367:mirSVR_highEffct hsa-miR-367:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.31E-85 7.31E-82 1.24E-84 1.14E-83 203 1064 "SYN3,NCKAP5,KLHL32,TMCC3,KIAA1211,MARCH4,FAM135A,PITPNM2,DPP10,PHF12,ATP2A2,ADAM23,ADGRB3,MPDZ,BCHE,HCN2,SYNJ1,CACNA1I,KALRN,CAMK2A,LDB2,MTMR7,SOCS6,NRXN3,HECTD1,AKAP5,CNRIP1,FAM171B,CRHBP,LRIG1,VCAN,SOCS5,SLITRK5,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,PLPPR4,CDON,CPEB2,PDCD6IP,ARRDC4,ABCC5,E2F5,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,HSPA12B,POLK,ATP13A4,SLC37A3,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,CHL1,IQGAP2,ERAP1,GHR,GLYR1,ZNF638,FERMT2,GPD2,GPR37,TPPP,DIDO1,PRDM5,HAS2,UBE2QL1,MIER3,HNMT,MSL1,SLC6A17,C2CD4C,KIT,LAMP2,LIG4,LMO2,NCOA7,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MEIS1,AFDN,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,P2RX7,GPR137C,GPR85,PIK3C2A,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,PDZRN4,TRHDE,STRN3,SCHIP1,ING3,CEP41,TMEM260,PTPRD,PTPRO,TMEM255A,ENOX1,OXR1,RASGRF2,RDX,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,ELP2,RPE,RPL15,FBXW7,BAALC,ABCA11P,AP1AR,SATB1,FNIP1,HES6,CPEB3,MYO18A,FBXO11,CNKSR2,DZIP1,ZNF430,SLC12A2,TET1,CPEB4,ZKSCAN3,DMRTC1,CDK5RAP2,TTC17,SNRPN,PDZD2,SOX11,MYCBP2,TEX2,PBLD,ITPRID2,ELOVL4,RGL1,PRRC2C,SYN2,SYPL1,SYT1,CAMTA1,DOCK9,SIK3,FAM200B,GALNT17,TPM1,SYNPO2,TRIO,SGK3,UGT8,VLDLR,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,TRIM9,ZSCAN26,MAP3K12,MFF,CADM2,EVI5,RNF103,NAV3,RGS7BP,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-548a-3p:PITA hsa-miR-548a-3p:PITA_TOP PITA 1.50E-85 8.38E-82 1.42E-84 1.30E-83 180 828 "KCNH8,FMNL2,CCDC85A,USP31,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,AMPH,CDC42BPA,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,SLC4A4,N4BP2L1,ADGRB3,SYNJ1,ARHGEF7,FUBP1,WASF1,CACNB4,CALB1,CALM1,PTBP2,RUNX1T1,SEPT7,CLGN,NOG,SRSF11,SOCS6,LHX2,CLTC,FAM19A5,QKI,BAG4,CLOCK,CDC42BPB,CREM,CRMP1,ERC2,PLCXD3,HDAC4,LONRF1,MATR3,DGKB,MYEF2,ZC3H11A,DDX46,FAM107B,DMD,USP3,HIPK3,KMT5B,EIF4G2,STARD3NL,EIF1,TAOK3,FGF13,FGFR3,SUCO,FOXO3,FAM49B,GABRB3,GABRG2,MSTN,AHDC1,MMADHC,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,SOX21,PSIP1,BACH2,MIER3,HLF,NEGR1,SMAP1,KIF2A,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,TTC13,PID1,CEP97,RBBP8,RADX,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,SOX11,SOX15,LMO3,CLASP2,SS18,ERBIN,ST5,RGL1,PLCB1,ANKRD12,CAMTA1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,TMEM121,ZFPM2,SLC44A1,TLR4,ERCC6L2,KCNE5,TUBB2A,RPRM,FLRT2,WIPF1,ZBTB14,ZNF711,ZFAND5,SMARCAD1,EMSY,STOX2,NAV3,KCNAB1,PCBP4,WNK3,PDSS2,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-3136:mirSVR_highEffct hsa-miR-3136:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-85 8.67E-82 1.46E-84 1.35E-83 219 1242 "KCNH8,CLK4,ABHD6,XKR4,CCDC85A,AXIN2,PTCHD1,BEND6,WDR35,ABCD2,MARCH4,PCDH10,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,TNRC6C,LINC00173,STK33,ZBTB10,CHRD,NCOA1,NUMB,ATP1B3,ZNF582,SLC2A11,N4BP2L1,DST,MTMR2,JAZF1,C5,CALB1,PRC1,CCNH,MTMR7,SLC16A4,LRRFIP1,TIGD7,CFL2,SOCS6,ABCG2,FAM19A5,QKI,CNR1,FAM149A,AKAP6,ABI3BP,CPS1,FAM171B,CLIP3,ARHGEF10,VCAN,SOCS5,PHACTR3,DZIP3,UBXN2A,RIMS2,RUBCN,HDAC9,RIPOR2,DGKB,YTHDC1,DDX46,GRIN3A,DMD,DTNA,DNAJB6,E2F5,E2F6,EBF1,KLHL5,YAF2,PHF20L1,EGFR,MBNL2,GOLGA7,KCTD3,EIF4G2,MRNIP,EIF1,RCAN2,RAB9B,F5,FAM198B,SCML2,CHST15,FGF1,FLT1,STAU2,MSANTD4,OGA,ERAP1,TUBGCP4,PCDH17,PPARGC1A,ZNF638,DCLK2,ZNF782,ADGRA3,DIDO1,SERP2,TNFAIP8L3,NEGR1,SHISA6,SMAP1,IDH3A,IL6ST,INPP5B,ITGAM,KCND1,KCNJ16,STXBP5,STMN1,HECTD2,NCOA7,LSS,MARK1,MAT2A,MBNL1,COL28A1,MSR1,NFE2L2,NRCAM,OCRL,OGG1,OXTR,PCDH9,PRTG,GNG2,ABCB1,ZNF655,PLCL1,PPP2R5E,RANBP3L,MAPK4,CNTLN,PTPRB,ACSM5,CEP97,USP47,HKR1,ERI2,FIGN,CCDC82,ALG9,CARF,CCDC102B,NEK11,ABCA11P,ATAT1,RYR3,ATXN2,ATXN7,SCN8A,SHC4,HKDC1,CHD9,ANKRD6,WDR37,ABLIM3,FAM81A,PEX26,PPP4R3A,KANSL3,ELMO2,BTBD7,GKAP1,MAST1,LIMCH1,ZNF415,SNRPN,PDZD2,SP4,CDK19,PBLD,NKAIN2,STXBP1,KLHL7,PRRC2C,ARHGEF9,PJA1,MCF2L,TCF4,ZFP90,TRIM2,CLASP1,SYNE1,PCDHA5,FRYL,MTMR14,TMPO,KAT6B,NPL,RGMB,STXBP4,SSBP2,TUBB1,FAM155A,PLEKHH2,USP1,BCL2L13,VLDLR,CLDND1,GUSBP1,ZNF711,ZNF28,LYPD6,ZBTB38,REEP1,FSTL5,ZXDA,EMSY,CADM2,MDH1B,NAV3,HRASLS,FZD3,RTN4,TIGD6,GAN" MicroRNA hsa-miR-509-3p:mirSVR_lowEffct hsa-miR-509-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-85 1.17E-81 1.96E-84 1.81E-83 210 1143 "EMILIN3,FMNL2,GALNT13,ADD2,AXIN2,TBC1D14,HFM1,TAOK1,CEP126,DPP10,LRCH2,GAS7,LGR5,ZFYVE28,ARNTL,ATP1A3,SLC4A4,ZNF583,RGS9,CFLAR,KSR1,MTMR3,CACNB4,KALRN,CAST,KRIT1,METTL6,DCLK1,MAGI1,TIGD7,CCPG1,NOG,SRSF11,ASIC3,CHN1,NDST3,ARHGEF6,CABP1,COL4A5,SLC35F1,RBM39,HAPLN1,PDE4DIP,CST3,DZIP3,SEC14L5,SNPH,MATR3,DGKG,DNAL1,PITPNC1,ELMSAN1,FBXL5,SNAP91,SGSM2,GRIN3A,NR1D2,DOCK2,DMTF1,DTNA,TMTC1,YAF2,EGFR,MBNL2,COPS4,GPHN,CEP78,PRMT5,ZNF589,FECH,IP6K2,FLT1,SLC37A3,EFCAB2,STAU2,GALNT15,LRRC37A6P,CYP46A1,PPARGC1A,RAB30,GNG4,STMN2,GRIA2,PRDM5,GRM8,FAM19A2,HAS2,PADI2,FRMD3,GABARAPL2,ZDHHC15,NEGR1,SOWAHA,RBPJ,KIAA1755,SCIN,INSM1,KLHL23,STMN1,LMO2,SYTL4,ASPRV1,AQP11,MBNL1,MIA2,KITLG,AFF1,XRRA1,ADAM22,MYO7A,ZNF862,NF1,NOVA1,DNHD1,GLIPR1L2,DPY19L2P2,PCDH8,PCSK1,NLGN3,SNX10,FAM216A,TRHDE,RETREG2,MINDY2,HYDIN,BDNF-AS,PTPRD,PTPRH,NKAIN1,TTC13,USP47,RAP1GDS1,MSANTD2,RDX,UBR7,CCDC82,SPIN3,SGSM1,STK32B,LRRK2,ATAT1,KCNIP1,RXRA,ATXN7,SCP2,COPZ1,KIF21A,KIF16B,CHD9,FBXO11,ST6GAL1,CNKSR2,PPP4R3A,PKNOX2,BTBD7,SLC22A4,ANKRD36,LIMCH1,MBD5,DOP1A,PDZD2,DOK5,ZNF423,DBNDD2,TSPYL2,RBM26,LARP4,NKAIN2,SS18,SEPT8,KLHL7,NECAB1,SYNE2,NUDT10,ADAMTS17,ARC,SYPL1,SLC37A2,ADGRL3,SMG6,TCEA1,CUX2,ZEB1,OBSL1,NSD1,PUM2,DICER1-AS1,AKTIP,TMPO,CSMD1,KAT6B,ELP5,TRIO,PDSS1,UGT8,VLDLR,GUSBP1,XPO1,ZIC1,ZNF24,TCEAL7,ANKS1B,EMSY,CADM2,RNF103,NAV3,FIP1L1,PARP11,PHTF2,DPF3" MicroRNA hsa-miR-548f:PITA hsa-miR-548f:PITA_TOP PITA 2.28E-85 1.28E-81 2.14E-84 1.97E-83 180 830 "KCNH8,FMNL2,CCDC85A,USP31,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,AMPH,CDC42BPA,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,SLC4A4,N4BP2L1,ADGRB3,SYNJ1,ARHGEF7,FUBP1,WASF1,CACNB4,CALB1,CALM1,PTBP2,RUNX1T1,SEPT7,CLGN,NOG,SRSF11,SOCS6,LHX2,CLTC,FAM19A5,QKI,BAG4,CLOCK,CDC42BPB,CREM,CRMP1,ERC2,PLCXD3,HDAC4,LONRF1,MATR3,DGKB,MYEF2,ZC3H11A,DDX46,FAM107B,DMD,USP3,HIPK3,KMT5B,EIF4G2,STARD3NL,EIF1,TAOK3,FGF13,FGFR3,SUCO,FOXO3,FAM49B,GABRB3,GABRG2,MSTN,AHDC1,MMADHC,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,SOX21,PSIP1,BACH2,MIER3,HLF,NEGR1,SMAP1,KIF2A,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,TTC13,PID1,CEP97,RBBP8,RADX,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,SOX11,SOX15,LMO3,CLASP2,SS18,ERBIN,ST5,RGL1,PLCB1,ANKRD12,CAMTA1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,TMEM121,ZFPM2,SLC44A1,TLR4,ERCC6L2,KCNE5,TUBB2A,RPRM,FLRT2,WIPF1,ZBTB14,ZNF711,ZFAND5,SMARCAD1,EMSY,STOX2,NAV3,KCNAB1,PCBP4,WNK3,PDSS2,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-302d:mirSVR_highEffct hsa-miR-302d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.33E-85 1.30E-81 2.19E-84 2.01E-83 239 1479 "KIAA1211,PTCHD1,MTUS1,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,ATP6V1G2,BACH1,MPDZ,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,SGCE,CA12,CALB2,MAGI1,CFL2,CHN2,CNOT8,TAOK2,ABCG2,C4orf33,AKAP5,IGDCC3,CNRIP1,ZNF385A,CPS1,CRHBP,ANKRD44,SNCAIP,ARHGEF10,SOCS5,CYBB,BOC,KIAA0586,DGKG,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,E2F6,EDN3,EDNRB,ANKRD46,HIPK3,YAF2,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,STX2,VPS26C,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,EFCAB2,MSANTD4,FYB1,MEGF11,IGSF5,TUBGCP4,ADAM28,GGTA1P,MALT1,COPS8,TOX3,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPR12,GPR34,PCLO,ATP2B1-AS1,UBE2QL1,ARHGAP36,ZDHHC15,SMAP1,MSL1,IDH3B,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,OPA1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,DRAM2,RASGEF1B,PRKACB,GRAMD1C,MASP1,SNRK,QRICH1,CNTLN,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,CCDC102B,RPE,MCMBP,RPS20,RTN1,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,ADGRL3,AGTPBP1,TBCEL,TCEA1,ZFP90,CUX2,ZEB1,SZT2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NACC2,NR2E1,TNS1,C9orf85,WBP2,RGMB,PPIL6,ZNF709,VLDLR,PCDH20,TRIM9,LYPD6,LAMP5,CADM2,PRTFDC1,PRDM8,PRDM10,RNF103,NELFE,PLSCR4,FAM13C,MRPL47,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-297:mirSVR_lowEffct hsa-miR-297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.89E-85 2.17E-81 3.64E-84 3.35E-83 249 1605 "XKR4,TMEM132B,GALNT13,RNF150,ESYT2,BEND6,SORCS2,TAOK1,FAM135A,ZFAT,PHF12,PKP4,VAT1L,LGR5,CDK13,ZBTB10,TMEM108,RIPK1,NRP2,DST,JAZF1,CACNB4,PTBP2,CH25H,ISPD,RUNX1T1,ZNF501,CCNH,MTMR7,SRSF11,CHN2,DGCR9,QKI,IGLON5,ARHGEF6,COL4A5,AKAP5,AHCTF1,ZFP28,CREM,CRHBP,AKAP12,GDA,SOCS5,SLITRK5,APPL1,PLCXD3,PUM1,RIMS2,KIAA0408,DOCK4,GPRASP1,DCAF8,ZNF337,LIN54,KIAA0586,INTS1,DGKG,GIT2,YTHDC1,MFAP3L,RHOBTB1,DMD,SLC12A6,DTNA,ABCC5,AASDH,WDPCP,EDNRB,HIPK3,TMTC1,EIF4G2,EIF5,TENM1,VPS13B,EPB41L2,RABEPK,STX2,NCALD,CEP85L,ZNF549,KATNAL1,EYA1,MRVI1,CEP78,ZNF589,FGF12,FGFR3,FHL1,POLK,SCARA3,EVL,UFM1,ST6GALNAC3,CSPG5,TVP23A,CHL1,GAD1,ZNF559,LRRC37A6P,PCDH17,LYVE1,GLI2,GPR34,PCLO,ATP2B1-AS1,GRIA2,DIDO1,ZNF496,MAP4K5,FRMD3,GABARAPL2,HNMT,TCEAL6,SHISA6,RBPJ,LRRCC1,ITGAM,SLC35G1,CYP27C1,LAMP2,LIFR,HECTD2,LYPLAL1,CHIC1,TM6SF1,SHC3,MEF2C,KITLG,POC1B,AFDN,XRRA1,MPP2,COMMD5,ADAM22,NEK1,CNOT4,DNHD1,NPTX2,NTRK2,FAM225B,OXTR,P2RX7,TREM2,CNTN3,DPY19L2P2,PCSK5,PDE3A,PDE4A,ENPP2,FAM98B,DUSP26,PLIN1,MTRF1L,EPB41L4B,MINDY2,PPM1B,PPP2R2B,LRRN3,PPP3CA,PRKAB2,HYDIN,KLK6,SNRK,PTN,PTPRB,CEP97,FAT4,OXR1,UBR7,RGS4,ZFHX4,GSTCD,RPL15,SPIN3,PTGR2,KCNIP3,RYR3,CCDC112,MRAS,SH3BGR,PPM1E,ARX,PPP4R3A,TRIM67,SLC12A2,SLC22A4,MAST1,ANKRD36,MBD5,CABCOCO1,ZNF415,DOP1A,ERC1,CDK19,RBM26,PBLD,SAMSN1,SSTR1,LARP4,ZSCAN29,DIP2A,NECAB1,PLCB1,COBL,ANKRD28,TACR1,CAMTA1,EXOC7,FAM208A,TBCEL,ZFP90,CUX2,ZEB1,DOCK9,SLC35G2,CYB561A3,ITGB3BP,NR2E1,KAT6B,C9orf85,AMACR,ANKRD20A2,FAM155A,ZNF781,GUSBP1,CFAP298,ZIC2,ZNF711,ZNF19,ZNF24,TRIM9,CELF4,REEP1,SPIRE1,UPF3A,DNALI1,EVI5,PRDM8,DNAH10,FZD3,DOCK8,KAT6A,ADAMTSL3,JMJD1C,TIGD6,FXR1,IFT88,SOCS4" MicroRNA hsa-miR-21*:mirSVR_highEffct hsa-miR-21*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.17E-85 2.89E-81 4.84E-84 4.45E-83 214 1193 "CLK4,SYS1,NDRG3,CCDC85A,TMCC3,PWWP2A,RNF150,ZNF608,MTUS1,KLHL13,PCDH19,SPOP,ALCAM,FAM135A,GPRASP2,MAP4K3,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,PHYHD1,TMEFF1,ARNTL,LINC00173,RIPK1,ADGRB3,ARHGEF7,CALM1,KALRN,CH25H,RUNX1T1,PRC1,CD38,TBRG4,SOCS6,B4GALT6,RAB33A,NRXN3,PPT2,STOML1,CLTC,CNN3,ARHGEF6,AKAP6,WHRN,SLC4A8,IGDCC3,CNRIP1,PREPL,SIPA1L1,VCAN,SOCS5,APPL1,PNPLA8,DOCK4,KCTD8,PABPC5,GIT2,DNAL1,DGCR5,MYEF2,ELMO1,LYPD1,SPOCK3,SEC16A,EXOG,DYNC1I1,PDCD6IP,DTNA,DTNB,ECM2,AASDH,EBF1,EDNRA,FRY,PHF20L1,EMX2,LRRC17,CEP85L,ETV1,RRAGB,SIRPB1,EYA1,RPS6KC1,ACSL4,FGF14,TMEM164,SMC2,UFM1,FAM49B,CELF1,STAU2,SARAF,AP4B1,TRAF3IP2,ZNF559,TUBGCP4,MSTN,ARFIP1,CYP46A1,TOX3,GPD2,CCDC184,GRIA2,KAT7,AP4S1,RABL2A,RNFT2,ARHGAP36,HNMT,ZIC5,NME9,ITGAM,JAK2,SLC35G1,KIF5A,LAMP2,PAXBP1,SMAD1,MBNL1,AFDN,MN1,COMMD5,MSI1,MSR1,MXI1,CNOT4,SLC11A2,OCRL,PAX6,PCSK5,PDE4B,PDE4D,ZDHHC8,PKD1,PLIN1,PDZRN4,TRHDE,PSAT1,MAGEL2,ING3,SEPT4,PPP1R1A,PPP3CA,VPS13C,PTPRO,NKAIN1,TMEM255A,ZNF493,RDX,ZMAT4,RGS4,RGS12,PBRM1,RNASEL,SETD5,TMLHE,CARF,ROBO2,PCMTD2,CCDC102B,BAALC,SPIN3,ADAL,RPS6KA2,CLIP1,SALL1,SEMA6D,CASC3,SGK1,ZFP30,FBXO11,RCOR3,KIF13A,TMCC1,MYO16,DOP1A,SP4,ITPRID2,ZNF302,ERBIN,ELOVL4,ADHFE1,KLHL7,SYNE2,COBL,CAMTA1,DMXL2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIRT1,DICER1-AS1,SLC44A1,TIAM1,TMPO,SYNPO2,TRIO,DCBLD1,VLDLR,WIPF1,PCDH20,SH3GLB2,EMSY,NAV3,FAM13C,AMN1,FXR1,RNF146" MicroRNA hsa-miR-1297:mirSVR_highEffct hsa-miR-1297:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.58E-85 3.68E-81 6.14E-84 5.66E-83 221 1274 "ACADM,CLK4,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HACE1,TXNDC16,SMIM17,LRCH2,ANK2,EP400,APAF1,APC,TNRC6C,RGS20,CDK13,CCDC74A,SLC4A4,LINC00847,BID,GPR146,BMPR1B,DST,FUBP1,SCAPER,WASF1,KALRN,KRIT1,USP6,SRSF11,SOCS6,CHN2,CLCN3,CLTC,TMEM184B,CNR1,AKAP7,COL4A5,BAG4,C2CD2,HAPLN1,SNCAIP,PLXNA4,DZIP3,ERC2,GREB1,RUBCN,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,DAPK1,PITPNC1,ARMCX2,JAKMIP2,HEPH,MFAP3L,C2CD2L,PLPPR4,SACS,WDR20,EXOG,GRIN3A,DMD,USP3,PDCD6IP,TMTC1,FSD1L,EIF4G2,EIF5,CALCRL,PAN3,VPS13B,EPHB1,ETV1,FAM198B,RPS6KC1,TMEM132C,CEP78,GORAB,FGF14,MEX3B,SEMA4D,UFM1,ZNF44,DISC1,ACSS1,SRCAP,PPARGC1A,TNRC6A,ZNF638,KCNMB4,GRB10,DIDO1,LINGO1,ADAMTS6,ZHX1,MIER3,HNF4G,CELF5,ZIC5,IL6ST,FAM69A,KCND2,SMAD1,MAP2,MARK1,MAT2A,MITF,AFDN,MMP16,ZNF680,BLOC1S2,ZNF92,MXI1,CCDC13,NEK1,CNOT4,SLC11A2,PCDH9,SLC10A4,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,FAM216A,PLCL1,PCDH18,PURG,ING3,FA2H,MINDY2,PPM1B,RANBP3L,CEP41,GRAMD1C,HYDIN,DIRAS2,VPS13C,PIGG,PTPN13,PTPRD,TTC13,ZNF615,PPP2R3C,ZCWPW1,UBR7,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,GSTCD,ARMH4,GLDN,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,GALNT10,MRAS,KIF27,CHD9,FBXO11,NLGN1,ZNF430,CCDC88A,TET1,MYH15,LIMCH1,TMCC1,USP33,ZC3H13,CLASP2,TROVE2,LARP4,STAC2,NECAB1,SYNE2,PLCB1,ANKRD28,PJA1,DNMBP,FAM208A,KLHL4,TCEA1,USP32P1,FRYL,C18orf54,AP4E1,ERCC6L2,FAM124A,AMACR,STXBP4,PPIL6,DCBLD1,ANKRD20A2,TTC3,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,MKRN3,ZBTB38,ANKS1B,EMSY,MDH1B,MPPE1,WNK3,PDSS2,PHTF2,RNF170" MicroRNA hsa-miR-1262:mirSVR_lowEffct hsa-miR-1262:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.79E-85 3.80E-81 6.33E-84 5.83E-83 242 1523 "CLK4,AS3MT,RNF157,ADD1,KIAA1211,WDR35,FAM135A,ZFAT,C6orf89,CCDC146,SFMBT2,PRX,NUMB,SLC2A11,LINC00847,RGS9,NRP2,DST,SYNJ1,MTMR3,BAIAP3,CACNA1B,CALB1,KALRN,USP2,P2RX6,LOC730101,MAGI1,NUMBL,SRSF11,ASIC3,NDST3,LHX2,SULT4A1,AKAP6,COL11A2,SMARCAL1,CRY2,ABCG1,SNCAIP,OSBPL3,PDE4DIP,FAM169A,RIMS2,RUBCN,BOC,ARHGAP32,GAPVD1,HDAC4,ZNF337,B3GAT3,TMEM130,POM121,WDR20,DMD,MED12,DMTF1,DPH1,DPYSL2,DRP2,TOM1,EIF5,C8orf37,RABEPK,ERBB2,ERBB4,ZNF549,ETV1,VPS26C,EYA1,CLVS1,ABCA8,CORO2B,RACK1,FKTN,PPP1R1B,OLFM1,FGFR3,POLK,FLT1,FOLR2,NBEA,UFM1,CAMKK2,KHDRBS3,CELF1,DLL3,HHIPL1,TVP23A,OGA,FYB1,MEGF11,GALNT15,B4GALNT1,ZNF274,GHDC,GCK,GGT7,DHRS4,TTBK1,RNPS1,RAB30,GPD1,MCHR1,SPACA9,SERP2,GRIN2D,CLASRP,RNF165,FAM107A,GUCY1B1,ATOH8,MAN1B1,HLF,HMGCL,ZNF181,LRRC25,KIAA1755,TJAP1,SCIN,SLC35G1,KCNH2,KIF5A,KIT,IPO5,KTN1,STMN1,MBD1,MITF,BLOC1S2,N6AMT1,MYO9A,NEXMIF,NF1,VWA2,CNOT4,NRCAM,NTRK2,NUCB2,ZNF827,DPY19L2P2,PCSK5,CDK18,ENPP2,DUSP26,FAM216A,TRHDE,SDK2,RETREG2,EPB41L4B,MINDY2,PPP1R1A,KANSL1,PRKACB,HYDIN,MASP1,TMEM104,PTCH1,PTN,PTPRD,PTPRE,PTPRN,RIPOR1,ZSCAN2,NKAIN1,FAM66C,NWD1,ZCWPW1,RADX,MSANTD2,RGS12,RNH1,ARMC5,CARF,ROBO2,NEK11,RPL15,ZNF671,TCP11L1,STK32B,RPS20,HSD11B1L,KCNIP3,HES6,SMPD3,STUM,FOXRED1,DZIP1,EPN2,DHX30,KANSL3,ANKRD36,SNRPN,TMCC1,FAM126B,TEX2,MCF2L2,DDN,LMO3,CLSTN2,ZNF302,SSTR1,ADHFE1,KLHL7,ZC3H4,PRRC2C,ARC,TACC1,ANKRD12,TAL1,PDLIM2,ALG1,DMXL2,ZEB1,PHF24,OBSL1,SIK3,PMS2CL,AP4E1,R3HDM1,KAT6B,PPIL6,TTTY15,UBE2H,CLEC2L,GORASP1,MGAT5B,PLPPR2,CCDC136,LAT2,PCDH20,ZIC1,ZNF28,EML6,EVI5,STOX2,PARP11,DOCK8,UBE3B,PHTF2,CASC15,FAM219B" MicroRNA hsa-miR-1271-5p:TargetScan hsa-miR-1271-5p TargetScan 8.27E-85 4.63E-81 7.69E-84 7.08E-83 183 866 "AS3MT,ADCY6,PTCHD1,HECW2,KCTD16,KIAA1324,PCDH10,ALK,GPRASP2,OGT,CDC42BPA,LRCH2,PHF12,ARHGDIA,CDK13,PDE8B,MARCH3,NUMB,DPY19L3,ADAM23,MTMR3,JAZF1,CACNA1G,LDLRAD4,CACNA1B,CACNA2D1,CACNB4,PRC1,LDB2,SCARB1,EVI5L,MAGI1,DLGAP2,CACNA2D2,FOXN3,QKI,MAP4K4,CNN3,COL9A1,MYRIP,IGDCC3,CLOCK,CDC42BPB,PREPL,AATK,LRIG1,RIMS4,PITPNM3,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,ARHGAP24,KIF26A,DNAL1,ELMO1,RHOBTB1,KIF19,E2F5,EBF1,EDNRA,FEM1B,FAM13A,PHF20L1,MBNL2,EGR3,EIF5,RGS17,PAN3,GPHN,RAB9B,ERBB4,NCALD,IGSF6,CEP85L,NRN1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,CELF1,NSG1,FUT9,FYN,B4GALNT1,FREM1,PCDH17,AIFM3,PCLO,PARD3B,GRIK4,KAT7,ATOH8,RASSF8,HAS2,FRMD5,BACH2,C2orf72,CDH20,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,MBNL1,CHIC1,PPM1L,MITF,ADAM22,MYO9A,NCAM2,NF1,NOVA1,NOVA2,NPTX1,NPTX2,IGSF11,CHAMP1,PAX6,PCDH8,PCSK5,CDK18,PDE4D,GPR85,PIK3C2A,PIK3R1,FAM216A,MAGEL2,EPB41L4B,PPP3CA,CEP41,CNNM2,EML5,PTPRG,PTPRN2,CEP97,RDX,PRIMA1,C12orf49,MCMBP,CSRNP3,MRAS,CCDC92,FAM81A,BTBD3,CCDC88A,ELMO2,ATF7IP,CPEB4,FAM126B,MYO16,FNBP1,CLASP2,PHLDB1,KLHL7,JMJD6,COBL,FBXW11,DOCK9,GPRIN3,AP4E1,CBX5,RUNDC3B,BCL2L13,RICTOR,REEP1,CADM2,EVI5,NAV3,FZD3,JMJD1C,FXR1,NETO2,GAN,LAS1L" MicroRNA hsa-miR-96-5p:TargetScan hsa-miR-96-5p TargetScan 8.27E-85 4.63E-81 7.69E-84 7.08E-83 183 866 "AS3MT,ADCY6,PTCHD1,HECW2,KCTD16,KIAA1324,PCDH10,ALK,GPRASP2,OGT,CDC42BPA,LRCH2,PHF12,ARHGDIA,CDK13,PDE8B,MARCH3,NUMB,DPY19L3,ADAM23,MTMR3,JAZF1,CACNA1G,LDLRAD4,CACNA1B,CACNA2D1,CACNB4,PRC1,LDB2,SCARB1,EVI5L,MAGI1,DLGAP2,CACNA2D2,FOXN3,QKI,MAP4K4,CNN3,COL9A1,MYRIP,IGDCC3,CLOCK,CDC42BPB,PREPL,AATK,LRIG1,RIMS4,PITPNM3,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,ARHGAP24,KIF26A,DNAL1,ELMO1,RHOBTB1,KIF19,E2F5,EBF1,EDNRA,FEM1B,FAM13A,PHF20L1,MBNL2,EGR3,EIF5,RGS17,PAN3,GPHN,RAB9B,ERBB4,NCALD,IGSF6,CEP85L,NRN1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,CELF1,NSG1,FUT9,FYN,B4GALNT1,FREM1,PCDH17,AIFM3,PCLO,PARD3B,GRIK4,KAT7,ATOH8,RASSF8,HAS2,FRMD5,BACH2,C2orf72,CDH20,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,MBNL1,CHIC1,PPM1L,MITF,ADAM22,MYO9A,NCAM2,NF1,NOVA1,NOVA2,NPTX1,NPTX2,IGSF11,CHAMP1,PAX6,PCDH8,PCSK5,CDK18,PDE4D,GPR85,PIK3C2A,PIK3R1,FAM216A,MAGEL2,EPB41L4B,PPP3CA,CEP41,CNNM2,EML5,PTPRG,PTPRN2,CEP97,RDX,PRIMA1,C12orf49,MCMBP,CSRNP3,MRAS,CCDC92,FAM81A,BTBD3,CCDC88A,ELMO2,ATF7IP,CPEB4,FAM126B,MYO16,FNBP1,CLASP2,PHLDB1,KLHL7,JMJD6,COBL,FBXW11,DOCK9,GPRIN3,AP4E1,CBX5,RUNDC3B,BCL2L13,RICTOR,REEP1,CADM2,EVI5,NAV3,FZD3,JMJD1C,FXR1,NETO2,GAN,LAS1L" MicroRNA hsa-miR-181a:PITA hsa-miR-181a:PITA_TOP PITA 9.18E-85 5.13E-81 8.50E-84 7.83E-83 178 817 "KCNH8,FMNL2,TMEM132B,CCDC85A,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,GAS7,CDC14B,SEMA4G,MADD,SLC4A4,ATP2B2,RNF182,ADGRB3,JAZF1,WASF1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,QKI,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,LONRF1,ELMSAN1,MFAP3L,ZC3H11A,POM121,SPOCK3,MTX3,WDR20,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,E2F5,KLHL5,FSD1L,MBNL2,EGR3,PAN3,NCALD,CLVS1,DLC1,MEX3B,PCYOX1,SYT3,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GRB10,GRIA2,CIT,ADAMTS6,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,IPO5,LIFR,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,HS6ST3,NEXMIF,ZC3H12B,NEFH,CNOT4,NOVA1,IGSF11,GPR137C,PCSK1,PRTG,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,PPARA,PPP2R5E,CEP41,CNNM2,PTPRE,USP47,FIGN,RFX2,PRIMA1,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,FNIP1,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,TMCC1,FAM126B,DOP1A,NMNAT2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,PRRC2C,MTCL1,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,SLC35G2,SIRT1,TNS1,NR2C2,ZIC2,ZNF28,SMARCAD1,SEMA3B,PHTF2,SOCS4" MicroRNA hsa-miR-181c:PITA hsa-miR-181c:PITA_TOP PITA 9.18E-85 5.13E-81 8.50E-84 7.83E-83 178 817 "KCNH8,FMNL2,TMEM132B,CCDC85A,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,GAS7,CDC14B,SEMA4G,MADD,SLC4A4,ATP2B2,RNF182,ADGRB3,JAZF1,WASF1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,QKI,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,LONRF1,ELMSAN1,MFAP3L,ZC3H11A,POM121,SPOCK3,MTX3,WDR20,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,E2F5,KLHL5,FSD1L,MBNL2,EGR3,PAN3,NCALD,CLVS1,DLC1,MEX3B,PCYOX1,SYT3,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GRB10,GRIA2,CIT,ADAMTS6,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,IPO5,LIFR,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,HS6ST3,NEXMIF,ZC3H12B,NEFH,CNOT4,NOVA1,IGSF11,GPR137C,PCSK1,PRTG,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,PPARA,PPP2R5E,CEP41,CNNM2,PTPRE,USP47,FIGN,RFX2,PRIMA1,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,FNIP1,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,TMCC1,FAM126B,DOP1A,NMNAT2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,PRRC2C,MTCL1,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,SLC35G2,SIRT1,TNS1,NR2C2,ZIC2,ZNF28,SMARCAD1,SEMA3B,PHTF2,SOCS4" MicroRNA hsa-miR-1979:mirSVR_lowEffct hsa-miR-1979:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-84 5.68E-81 9.39E-84 8.64E-83 277 1972 "AS3MT,NDRG2,TMEM132B,ADCY6,ADORA2A,KIAA1211,ADRA1D,AP2A2,TAOK1,SEMA6A,PDZD4,AMPD2,OGT,FGD2,SUGT1P4-STRA6LP-CCDC180,UPRT,AQP6,MARCH3,MARK4,SLC4A4,EIF4G3,STX16,ZNF583,DPY19L3,TTLL9,LINC00847,MTMR2,CACNA1B,DDR1,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2G,CLDN10,SLC16A4,CD38,C1orf52,CDH2,C7orf61,FBXO7,QKI,HECTD1,COL4A5,COX4I1,CRY2,CSF1,LRIG1,CSNK1E,VAC14-AS1,SLITRK5,TCAF1,ARHGAP24,DCAF8,KCTD8,IST1,DGKB,SCRN1,IP6K1,DBI,B3GAT3,KIAA0753,GUCD1,PLPPR4,GRIN3A,RAB39B,DOCK2,PDCD6IP,RCAN1,TOM1,SEZ6L2,FCF1,CNNM1,RASGRP1,YAF2,CELSR3,MBNL2,EIF5,DCTN4,COQ7,LRRC17,RABEPK,ZNF549,ETV1,NRN1,F5,CLVS1,ABCA8,ZNF461,CEP78,FCGR3A,FKTN,FDFT1,ZNF589,FGF1,OLFM1,SPSB4,FOXF2,SYNCRIP,FLNC,ATP6V1H,OGA,MEGF11,HRASLS5,GABRG1,TMEM8B,DISC1,LRRC37A6P,ALDH1L1,GCNT2,GGT7,CRCP,GNAL,GPD1,PCLO,PLCD4,CLASRP,FAM19A2,RNF165,PSIP1,MAN1B1,NCKAP1L,ARHGAP36,ELOVL5,SYNPO,CPT1C,SHISA6,FAM95B1,IDH3B,C2orf72,NKD1,KIAA1755,IL6ST,INPP5B,KIF5A,A1BG-AS1,IPO5,STMN1,SYTL4,NCOA7,PACRG,GPR155,MAP4,CHST6,TM6SF1,MMP16,GIT1,BLOC1S2,RTL5,NEXMIF,ZNF862,NF1,NPTX2,CLDN11,DPY19L2P2,PDE1C,OLA1,ABCB1,ZNF655,CCSER2,PLCB2,PLXNB1,PURG,ANKRD16,STRN3,EPB41L4B,TATDN3,RASGEF1B,PRKCB,MASP1,NDUFS7,PIGG,PTPRO,ACSM5,USP47,RASGRF1,CRTAC1,ZMAT4,TRIM68,RFX2,RGS3,RIC8B,PBRM1,LGI2,SUGCT,TMLHE,ALG9,ARMC5,GSTCD,ELP2,EPHA10,SPIN3,GLDN,SGSM1,TCP11L1,MAP6D1,MEG3,ATAT1,KCNIP3,FAM192A,ATXN7,ZFP2,SGK1,KIF21A,FERMT1,CHD9,ST6GAL1,WDR37,ABLIM3,SLA,PPP4R3A,DHX30,PKNOX2,SLC6A8,ARHGEF40,SLC9A5,SLC14A1,NAPB,COA1,INTS9,MAPKBP1,SNRPN,RBM34,USP33,BDP1,SP4,TEX2,UNC5B,PEG10,ITPRID2,NKAIN2,PHLDB1,SEPT3,NSFL1C,NECAB1,COBL,AGTPBP1,SIN3B,SLC19A3,USP32P1,GPRIN3,HIF3A,CYB561A3,C18orf54,ZNF106,GALNT17,RELL2,ACTR6,TLR4,ERCC6L2,CSMD1,NR2C2,TRO,TSN,FAM155A,UBE2H,VIPR2,RICTOR,GUSBP1,ATP6V0E2,CRB2,SPIRE1,ZNF213,UPF3A,EMSY,STOX2,ADAMTS9,PPP1R3F,FIP1L1,WNK2,PDSS2,HNRNPA3,CASC15,TTC7A,GAN,FAM198A" MicroRNA hsa-miR-628-5p:mirSVR_lowEffct hsa-miR-628-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-84 7.32E-81 1.21E-83 1.11E-82 251 1639 "RALGAPA1,KCNH8,ABR,ACADM,NCKAP5,SYS1,TMEM132B,ADCY6,RNF150,BEND6,KIAA1324,SMIM17,ALCAM,ARHGAP20,ZFAT,EP400,MAGEE2,SHROOM2,AQP6,CDC14B,CDK13,SLC2A11,NRP2,DST,FUBP1,CA8,CACNB4,HIP1R,METTL6,MTMR7,CBFA2T2,SCARB1,ENTPD6,DCLK1,LOC730101,LARGE1,TIGD7,NOG,SOCS6,CNN3,AKAP7,ARMC8,SLC4A8,RTTN,MYRIP,ZFP28,SLC35F1,CRY2,TRIM69,CS,SNCAIP,SUSD5,PDE4DIP,PLXNA4,DZIP3,RUBCN,CYBB,ARHGAP32,HDAC4,DGKB,SCRN1,AIF1L,JAKMIP2,ELMO1,SV2B,WDR20,NYAP1,USP3,DPH1,SLC25A18,PDCD6IP,DTNA,E2F5,E2F6,EDNRB,PHC2,TMTC1,FAM13A,IRAK4,ENO2,SRRM1,ZNF549,SPEG,MRPL37,ANKMY1,RASL12,RRAGB,HSPA12B,CORO2B,CEP78,FKTN,GTF2IRD2,POLK,FLNC,NELFCD,TMEM107,SMC2,STAMBP,KHDRBS3,STAU2,MEGF10,SIGLEC8,C15orf41,DISC1,INPP5K,TUBGCP4,MMADHC,FREM1,GGT7,PPARGC1A,LYVE1,LNX1,LILRA2,GRIA2,FAM19A2,ZBTB49,RABL2A,FAM107A,GUCY1B1,FRMD3,MIER3,HMGCR,ZDHHC15,SHISA6,IRF8,SCIN,IL6R,ZNF678,CREG2,KIF5A,CYP27C1,SFXN5,PAXBP1,PACRG,CHIC1,MEF2C,AFDN,COL28A1,SAMD5,NRBP2,MYO5A,MYO6,ZNF862,HNRNPM,P2RY13,NEK1,NME4,DNHD1,SLC11A2,NTRK2,NTRK3,CNTN3,PCDH8,PRTG,GNG2,PFKFB4,NALCN,PLCB2,PDZRN4,TRHDE,LRP12,MINDY2,CCDC144B,PPP5C,RASGEF1B,PRKACB,MAPK4,MASP1,CNTLN,NCR3LG1,BDNF-AS,ZSCAN32,PTPRB,PTPRE,PTPRG,ACSM5,ACSS3,CCDC40,RASGRF2,RBBP6,RET,ERI2,UBR7,RGS12,TMLHE,KIRREL1,YY1AP1,ARMH4,ZNF671,GLDN,ADAL,HSD11B1L,DGLUCY,SALL1,SCN8A,GALNT10,CPEB3,SHC4,AMBRA1,ST6GAL1,ANKRD6,PPP4R3A,LIMCH1,SNRPN,TEX2,SPART,ITPRID2,ELOVL4,CEP68,DIP2A,PHLDB1,VPS13A,FAM208A,ADGRL3,TCF4,TPCN2,TRIM2,SYNE1,SIK3,VWCE,FAM200B,ZMAT3,AKTIP,SLC44A1,MTMR14,TK2,NR2E1,PPIL6,SSBP2,CLHC1,SGK3,FAM155A,WIPF1,ZNF711,ATP6V0E2,ZNF70,MKRN3,TMEM237,FSTL5,SPIRE1,FTSJ1,EMSY,PRDM8,PRDM10,FIP1L1,PLSCR4,FZD3,UBE3B,HNRNPA3,FRMD6,GAN" MicroRNA hsa-miR-223*:mirSVR_highEffct hsa-miR-223*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-84 7.97E-81 1.31E-83 1.21E-82 219 1256 "RALGAPA1,TMEM132B,GALNT13,BEND6,KLHL13,WDR35,ABCD2,DPP10,LRCH2,LCORL,LGR5,TMEFF1,ZBTB10,SLC4A4,EIF4G3,NRP2,SYNJ1,SYNJ2,FUBP1,WASF1,CALM1,VXN,SEPT7,CDH2,LRRFIP1,SRSF11,SLIT2,EPS15L1,CLCN3,CLTC,FAM189A2,ABCG2,C4orf33,SRP14-AS1,ARMC8,SLC35F1,FAM171B,ENTPD4,RBM39,GDA,ABCG1,ARHGEF10,OSBPL3,CSNK1G3,VCAN,CNTNAP2,DZIP3,CCDC144A,CYBB,GAPVD1,DCAF8,LIN54,MATR3,ELMSAN1,MYEF2,FBXL5,TMEM130,EXOG,MED12,NR1D2,ECM2,GOLT1B,EBF1,SNX29,EDNRB,FCF1,YAF2,PHF20L1,RCAN2,DENND4A,ETV1,EYA1,CLVS1,RPS6KC1,ACSL4,TAOK3,DLC1,CEP78,FGF1,FGF12,PRKAG2,SUCO,MEX3B,FLT1,PSD2,HVCN1,TPK1,ATP2C1,FYB1,GABRB3,GABRG2,ZNF234,ERAP1,C15orf41,DISC1,SULT1C4,MMADHC,TNRC6A,MSL3,GNAO1,GPD2,PCLO,DIDO1,RNF165,GUCY1B1,HAS2,DDX19B,HLF,LRRC75A,ZNF546,RBPJ,METTL21A,KCNH2,KCNJ16,LAMP2,PAXBP1,PIK3AP1,MATN3,MIA2,POC1B,AFDN,MMP16,LAYN,NEXMIF,ZC3H12B,NF1,NRCAM,NTRK3,GPR137C,ETFRF1,PIK3C2A,PCDH18,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPARA,TATDN3,RANBP3L,EPDR1,MAPK9,CNTLN,BDNF-AS,STK32A,PID1,TMEM255A,ZNF493,OXR1,MSANTD2,RDX,REV3L,FIGN,PBRM1,TMLHE,CARF,PCMTD2,CCDC102B,TCP11L1,LRRK2,SEMA6D,FNIP1,GALNT10,CPEB3,FUZ,CHD9,SLC12A2,RCOR3,TTC17,MBD5,CMTR2,SNRPN,MYO16,SP2,KDM4C,SST,STAU1,TMEM150C,SYPL1,TACC1,ANKRD12,EXOC7,ALG1,SYNE1,DOCK9,SLC19A3,PCDHB4,SLC35G2,PCDHA1,CCDC173,FAM200B,PMS2CL,ZFPM2,AKTIP,NPL,PDSS1,RUNDC3B,AMACR,CLHC1,SGK3,TUBB1,RPL7L1,BCL2L13,RBFOX3,WIPF1,P2RY12,CLDND1,ZIC2,KCNT2,TRIM9,ZNF195,PRDM10,RNF103,WNK3,RGS7BP,KAT6A,PHTF2,RNF170,NHSL1,NETO2" MicroRNA hsa-miR-939:mirSVR_lowEffct hsa-miR-939:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-84 8.93E-81 1.47E-83 1.35E-82 245 1566 "ASPHD1,CLK4,KDM5D,NDRG2,GALNT13,AP2A2,TBC1D14,KIAA1324,C1QTNF1,SPOP,USP35,CARNS1,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APOC2,BCAS1,CDK10,PRX,ARHGDIA,ARNTL,LINC00173,CDK13,CCDC74A,ZSCAN18,PCDHGB4,TMEM108,EIF4G3,ALDH7A1,KIF1A,GPR146,CFLAR,KSR1,CFAP410,CALB2,KALRN,CAMK2A,CBFA2T2,ENTPD6,DGKI,AP4M1,DCLK1,EVI5L,LOC730101,TAOK2,NRXN3,ABCG2,TMEM184B,SRP14-AS1,AKAP6,COL11A2,GAL3ST1,IGDCC3,ZNF385A,NCOR2,CLIP3,TRIM69,AATK,CSNK1E,OSBPL3,VCAN,RIMS4,VAC14-AS1,PLXNA4,GREB1,ARHGEF4,CCDC144A,ZNF337,SCRN1,ZNF804A,KLHL3,SPOCK3,SGSM2,DLX1,DNM1,RCAN1,ABCC5,EBF1,PHC2,OPTN,CELSR3,SUGP2,RASA4,IRAK4,CERCAM,ELN,EPB41,EPB41L2,EPHB1,ERBB4,SPEG,RACK1,FCGR1A,FCGR1B,ZSCAN30,KAT8,SPSB4,TMEM164,AMOTL2,MEGF10,GABBR1,GABRA3,GHDC,CPLX2,ALDH1L1,GGT7,GLUL,AIFM3,POLL,DCLK2,GPR12,PCLO,ADAMTS13,GSTM5,FAM107A,ATOH8,FAM222A,ZHX1,LRRC75A,SCIN,INPP5B,INSM1,METTL21A,KCNN1,CREG2,LINC00634,ZFYVE27,MAP4,MAP6,MGAT3,MID1,XRRA1,MN1,MSI1,MYO7A,FXYD7,CCDC13,NOVA1,SMIM11A,NUCB2,TBC1D25,GPR137C,ZNF827,PCDHGC3,CDK18,PDE1B,PDPK1,PFKFB3,KCTD15,FAM216A,FXYD1,PLXNB1,SDK2,POLR2F,PPP2R5E,KANSL1,NKAIN4,CEP41,NDUFS7,WDR25,PTPRE,PTPRH,USP47,FAM66C,IQSEC3,NWD1,DUSP15,DPF2,C12orf49,KLHDC8A,ARMC5,ELP2,SNX22,GLDN,STK32B,EMID1,ZNF331,COPZ1,FAM102A,FERMT1,PPP4R3A,KANSL3,PKNOX2,SLC11A1,LGI3,ARFGAP1,GKAP1,OGDHL,INAVA,MAPKBP1,SNCA,FAIM2,DOP1A,PDZD2,ZSWIM8,SPTB,DDN,CAMTA2,SSTR2,ZC4H2,SSPO,STAU1,RHBDL3,SYN1,COBL,SLC37A2,TAL1,SMG6,SIN3B,CUX2,ZEB1,USP22,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PHF24,FAM189A1,PCDHB4,ARHGAP9,SIK3,RNF216P1,GALNT17,ICAM5,ERCC6L2,CSMD1,RGMB,ZNF346,KCNE5,CLEC2L,UBTF,OSBP2,CLIP2,LAMP5,INTS3,URM1,UBE3B,PHTF2,TTC7A" MicroRNA hsa-miR-127-5p:mirSVR_highEffct hsa-miR-127-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-84 9.81E-81 1.61E-83 1.48E-82 198 1025 "ADD1,ADRB2,TAOK1,PCDH10,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,LGR5,CADPS,PDE8B,ZBTB10,STX16,ZNF583,N4BP2L1,CA8,CACNB4,CAMK2G,RGN,LRRFIP1,TIGD7,CCPG1,CLGN,SRSF11,RAB33A,CNR1,ARMC8,SLC4A8,FAM171B,CREM,MROH8,PITPNM3,PUM1,HDAC9,ARHGAP24,ARMCX4,YTHDC1,KIAA0753,DDX46,SACS,SV2B,HS3ST2,CASP8AP2,ACOT8,DNM1L,HIPK3,YAF2,FAM13A,PHF20L1,ASB3,DCTN4,VPS13B,ENPP6,DENND4A,TLR7,ADGRV1,SCML2,FCGR1A,BAIAP2,POLK,RGPD5,ZBED3,UFM1,OGA,MEGF10,GALC,B4GALNT1,LRRC37A6P,GDF9,SESN1,RAB30,TNRC6A,ZNF638,LOXL3,MCHR1,PLCD4,GUCY1B1,C9orf129,ZDHHC15,KNDC1,LRRCC1,ZNF678,FAM69A,INSM1,KPNA5,PAXBP1,SHC3,MEIS2,NCAM2,NEFM,NEK1,NELL2,NF1,DNHD1,SLC11A2,NUCB2,GLIPR1L2,PCSK1,PCSK5,CYTL1,PIK3R1,SNX10,ZFYVE21,GPSM2,MINDY2,TATDN3,KANSL1,MAPK9,HYDIN,TMEM104,TMEM260,PTPRB,PTPRE,PTPRG,PTPRO,PID1,RAD17,ENOX1,OXR1,RASGRF2,GTDC1,DCUN1D2,ATP8B4,ZNF354C,SEMA6D,SATB1,ATXN7,SUPT20H,COPZ1,SH3BGR,FERMT1,CPEB3,FBXO11,FNDC3A,FHOD3,CNKSR2,NUBPL,DHX30,MYH15,RCOR3,CMTR2,DOP1A,SP4,HECW1,SPP1,KDM4C,UNC5B,SPART,POGZ,SST,SSTR2,ZSCAN29,SEPT8,CEP68,RGL1,DIP2A,ADHFE1,SYNE2,SYN2,ANKRD28,MTCL1,MCF2L,KIAA1107,RPGRIP1L,CLASP1,SZT2,SYNE1,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,CCDC173,SIK3,ZFPM2,BHLHB9,ERCC6L2,TMPO,FAM124A,C9orf85,UBTF,CLDND1,XRCC4,ZNF23,MKRN3,LYPD6,ZSCAN26,UPF3A,CADM2,KCNAB1,EPM2A,RGS7BP,PHTF2,FBXO36,JMJD1C" MicroRNA hsa-miR-337-3p:mirSVR_lowEffct hsa-miR-337-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.79E-84 9.99E-81 1.64E-83 1.51E-82 218 1246 "SYN3,ACTN1,XKR4,KLHL32,ADD2,USP31,KIAA1211,MTUS1,RTL9,SORCS2,OSBPL8,ARHGAP20,LRCH2,MAP4K3,PKP4,APBB2,USP37,STK33,MARK4,EIF4G3,CFLAR,BMP7,FUBP1,JAZF1,CFAP410,ISPD,USP6,P2RX6,CD38,DGKI,CCPG1,COPB2,CHN1,B4GALT6,MAP4K4,CNN3,ARHGEF6,CNR1,IQCK,BAG4,ZFP28,NRG2,CRHBP,GDA,SEC24C,LRIG1,CST3,SLITRK5,KIAA0040,APPL1,PLCXD3,RIMS2,ARHGAP32,GAPVD1,KCTD8,DGKB,GIT2,YTHDC1,ZNF804A,PLPPR4,SNAP91,SV2B,GRIN3A,RAB39B,USP3,DTNA,DNAJB6,GOLT1B,EBF1,ANKRD46,KLHL5,TMTC1,YAF2,PHF20L1,RASA4,AASS,TENM1,PAN3,ENPP6,ERBB4,EXTL2,FKTN,KAT8,GORAB,HPCAL4,SEC23B,PCYOX1,SYNCRIP,SEMA4D,ATP13A4,TMEM107,PDLIM5,HRASLS5,CHL1,GABRG1,TRAF3IP2,ACSS1,ARFIP1,ADAM28,TCERG1,RAB30,ZNF638,LUZP2,FERMT2,GPD2,LPAR4,GPR37,GRM8,ZBTB49,IRAK3,RASSF8,SYNPO,ZDHHC15,SMAP1,IGF1,SCIN,STXBP5,CYP27C1,LAMP2,LIFR,LIMS1,NCOA7,ZFYVE27,MATN2,CHIC1,TM6SF1,MEF2C,MEIS1,MITF,ZNF680,ZNF92,MYO6,MYO9A,NF1,OXTR,ETFRF1,PCSK5,PDPK1,PFKFB2,STRN3,LRP12,SH3KBP1,MINDY2,PPP2R5E,RANBP3L,EPDR1,SAMD9,PTN,TMEM260,PTPN13,PTPRB,PTPRD,C1orf109,ZSCAN2,OXR1,KHDRBS2,CRTAC1,RET,ERI2,RGS12,ALG9,PCMTD2,RPL15,KIAA0895L,MCMBP,LRRK2,ABCA11P,ATAT1,ATXN2,FNIP1,NLGN1,SLC8A1,ELMO2,BTBD7,ANKRD36,SNAP25,SNCA,MBD5,TMCC1,FNBP1,MYCBP2,SPP1,TSPYL2,LARP4,NKAIN2,ERBIN,PLCB1,SYN2,C12orf76,KIAA1107,KLHL4,ATMIN,TCF4,TRIM2,TCF12,PCDHGB7,DOCK9,ZNF106,RGMB,ZNF346,PPIL6,SSBP2,HIRA,RPL7L1,FAM155A,VLDLR,ZFP37,REEP1,POLR3H,ANKS1B,FTSJ1,STOX2,RNF103,URM1,FAM47E,MPPE1,PLSCR4,ACTR3B" MicroRNA hsa-miR-373:mirSVR_highEffct hsa-miR-373:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.97E-84 1.10E-80 1.80E-83 1.66E-82 238 1482 "KIAA1211,PTCHD1,MTUS1,AK2,SPOP,ALCAM,ABCD2,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,RGS20,STK33,STX16,DPY19L3,BACH1,MPDZ,BID,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,SEPT7,ZBED1,LRRFIP1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,AKAP5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,HAPLN1,ANKRD44,GDA,ARHGEF10,SOCS5,CYBB,BOC,HDAC9,KIAA0586,DCTN1,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,E2F6,EDN3,EDNRB,ANKRD46,HIPK3,YAF2,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,STX2,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,FYB1,IGSF5,TUBGCP4,ADAM28,GGTA1P,MALT1,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPR12,GPR34,PCLO,FICD,UBE2QL1,ARHGAP36,ZDHHC15,SMAP1,MSL1,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,PIK3AP1,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NCF2,NELL2,NF1,NRCAM,NTRK3,OCRL,OGG1,OPA1,PCDH9,PDCD2,PFKFB2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,ANKRD16,TRHDE,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,PTPRG,CEP97,TMEM255A,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,FIGN,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,MCMBP,RPS20,SHC4,CHD9,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,RGL1,SULF2,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,SYT1,CAMTA1,TBCEL,ZFP90,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,PLEKHH2,ZNF709,CCDC14,VLDLR,XPO1,KCNT2,TRIM9,LYPD6,LAMP5,CADM2,PRTFDC1,PRDM8,PRDM10,NELFE,PLSCR4,DNAH10,FAM13C,MARCH8,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-483-3p:mirSVR_lowEffct hsa-miR-483-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.99E-84 1.11E-80 1.82E-83 1.67E-82 243 1543 "KCNH8,ABR,ADCY6,RNF157,AXIN2,ADORA2A,OLMALINC,INTS2,KCTD16,OSBPL1A,CARNS1,ALK,AMPD2,LRCH2,FGD2,ARMC12,SUGT1P4-STRA6LP-CCDC180,APBA2,APC,EPB41L5,MAGEE2,VAT1L,MADD,RASL11B,DOCK11,ADAM23,ADGRB3,KSR1,DST,WASF1,MYRF,CA4,CACNB4,CALB2,ZNF555,KALRN,PTBP2,CBLN1,CBS,USP6,P2RX6,ENTPD6,C1orf52,ZNF445,MAGI1,RCBTB2,B4GALT6,CPNE6,MAP4K4,SMARCAL1,HINFP,ANKRD44,CSF1,RGS6,SUSD5,PHACTR3,PLXNA4,DZIP3,KIAA0040,UBXN2A,RUBCN,GAPVD1,RIPOR2,MAML1,SCRN1,IP6K1,MFAP3L,DDX46,GRIN3A,DMPK,NYAP1,DPP6,PDCD6IP,ARRDC4,DTNA,DTNB,ECM2,DNAJB6,SEMA3D,PHF20L1,MBNL2,KMT5B,EIF4G2,ING4,ELN,PAN3,RCAN2,MTSS1L,RRAGB,MRVI1,DLC1,RACK1,FCGRT,FDFT1,ZNF589,FGF12,FGFR1,TMEM164,SUCO,SCARA3,NOP56,SMC2,CAMKK2,ATP2C1,ERGIC3,STAU2,DOT1L,MEGF11,HRASLS5,GALC,SIGLEC8,DISC1,SEPT9,INPP5K,LRRC37A6P,ALDH1L1,GFER,GHR,SPIN1,KDM2B,RAB40B,STON1,PLCD4,BTN2A1,GSTM5,RNFT2,ATOH8,NCKAP1L,HMGCL,HP,HSF2,FAM95B1,SHISAL1,IGF1,TJAP1,ZNF678,ITPKB,KCNJ16,STXBP5,L1CAM,CAMK2N2,PAXBP1,PACRG,MBP,PPM1L,MITF,AFF1,AFDN,SAMD5,NCF2,SLC11A2,OPA1,CLDN11,CNTN3,ZFYVE21,SDK2,RETREG2,PPP2R5E,PPP5C,HYDIN,SNRK,WDR25,PIGG,PTPRG,TMEM255A,FAM66C,ROGDI,GAL3ST4,TRIM68,RFX2,RIC8B,RNH1,TMLHE,EXD2,ARMC5,GSTCD,CCDC102B,MRAP2,EPHA10,ATP8B4,ABCA11P,FNIP1,COPZ1,ST6GAL1,DZIP1,SLA,FAM81A,PREX2,DHX30,KANSL3,PKNOX2,CCDC88A,SLC12A2,ZNF334,NAPB,BTBD7,ZFP1,SMARCD3,SNRPN,TRERF1,ZSWIM8,KDM4C,UNC5B,IQSEC2,TSPYL2,MCF2L2,NFASC,SS18,SSPO,STAU1,ELOVL4,SULF2,DNAJC9,SYP,SYPL1,SLC37A2,TACC1,SATB2,SYNE1,SLC19A3,USP32P1,DICER1-AS1,TIAM1,TLR4,RIMBP2,TNS1,NPL,TPM2,ZNF346,RUNDC3B,KCNE5,ZKSCAN5,PLPPR2,TBC1D15,CFAP298,TRIM9,CRB2,CELF4,ZBTB38,FTSJ1,UPF3A,DHX33,ACTR3B" MicroRNA hsa-miR-449c:mirSVR_highEffct hsa-miR-449c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.78E-84 1.56E-80 2.54E-83 2.34E-82 200 1049 "NDRG3,ADD2,ADORA2A,ZNF608,KCTD16,KIAA1324,ZNF578,TAOK1,ALCAM,FAM135A,ANK2,SUGT1P4-STRA6LP-CCDC180,TMEFF1,ZBTB10,ATP1B3,DOCK11,ADAM23,CFLAR,SYNJ1,JAZF1,WASF1,CACNA1A,CALB1,THSD7A,PTBP2,CBLN1,CD86,DGKI,MAGI1,DLGAP1,CHN1,EPS15L1,SULT4A1,HECTD1,FHL5,SEC31B,PREPL,ENTPD4,NCOR1,CS,SIPA1L1,SOCS5,APPL1,PNPLA8,PUM1,PPP6R2,RIPOR2,ZFYVE16,CENPL,TMEM170A,ELMSAN1,RHOBTB1,USP3,DPP6,DTNA,DNM1L,E2F5,EDIL3,SEMA3D,CELSR3,APH1A,MBNL2,TENM1,PLEKHA1,CALCRL,VPS13B,GPHN,NRN1,FAM198B,FDFT1,FGF14,FHL1,RGPD5,C2orf88,WDR83,FAM49B,STAU2,MSANTD4,GABRA3,IQGAP2,TUBGCP4,MSTN,MALT1,TOX3,MAP7D2,GPD2,FUT10,STMN2,RNFT2,MAP4K5,FRMD3,ELOVL5,AGFG1,SHISA6,INSM1,ITPKB,KTN1,LAMP2,PAXBP1,NCOA7,LSS,MAN2A2,MAT2A,MBP,MITF,MYCN,MYO9A,NEK1,NF1,CNOT4,CNTN3,ABCB1,PIK3C2A,XRN1,JAKMIP1,PLIN1,EXOSC10,ING3,MAPK4,MASP1,VPS13C,ELOVL2,PTPRG,QDPR,USP47,RDX,TRIM68,ERI2,FIGN,RGS4,SLC25A36,RIC8B,TMLHE,SPIN3,ATP8B4,ATAT1,SCN7A,SCP2,HSPA4L,ANKRD6,PPP4R3A,SLC12A2,DMRTC1,CDK5RAP2,INTS9,MYO16,FAM219A,HECW1,MYCBP2,SPP1,ZC3H13,CDK19,ATP10B,CLASP2,ITPRID2,ZC4H2,NKAIN2,ERBIN,ADHFE1,SULF2,VPS13A,SYT1,MTCL1,FAM208A,ATMIN,ZEB1,TRIM2,SYNE1,GPRIN3,ITGB3BP,TLR4,RIMBP2,PRRT1,DCBLD1,KCNE5,TSN,HIRA,UBTF,WIPF1,CLDND1,PCDH20,ZNF540,ZNF74,FSTL5,ZNF184,ANKS1B,EMSY,CADM2,DNALI1,SLC38A1,ADAMTS9,NAV3,FAM47E,FBXO36,CASC15,JMJD1C,NHSL1,NETO2,NETO1,JPH3" MicroRNA hsa-miR-30a:PITA hsa-miR-30a:PITA_TOP PITA 3.42E-84 1.92E-80 3.10E-83 2.85E-82 182 863 "ADRA1D,LRFN2,AP2A1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,USP37,PPP4R4,TMEFF1,CADPS,ATP2B2,NRP2,CALB2,SPAG9,USP6,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,ABI3BP,ZNF521,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PLCXD3,FAM131B,DOCK4,MATR3,MAML1,YTHDC1,JAKMIP2,MYEF2,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,EPB41,EPB41L2,STX2,EXTL2,AMOTL2,MEX3B,OGA,CHL1,TRAF3IP2,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,NEFM,NF1,SMIM11A,NTRK3,PCDH9,PDE4D,TMOD2,EPB41L4B,PPP2R5E,CEP41,WBP1L,ELOVL2,PTPN13,PTPRD,USP47,OXR1,REV3L,PRRT2,FIGN,SETD5,ALG9,CARF,SEMA6D,SBF1,SCN8A,PPM1E,KIF16B,CPEB3,FNDC3A,FHOD3,NLGN1,FAM81A,WDR47,PKNOX2,TET1,CPEB4,TMCC1,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,TCF4,DMXL2,SATB2,SIRT1,TMEM121,RIMBP2,R3HDM1,PDSS1,TRPS1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30d:PITA hsa-miR-30d:PITA_TOP PITA 3.42E-84 1.92E-80 3.10E-83 2.85E-82 182 863 "ADRA1D,LRFN2,AP2A1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,USP37,PPP4R4,TMEFF1,CADPS,ATP2B2,NRP2,CALB2,SPAG9,USP6,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,ABI3BP,ZNF521,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PLCXD3,FAM131B,DOCK4,MATR3,MAML1,YTHDC1,JAKMIP2,MYEF2,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,EPB41,EPB41L2,STX2,EXTL2,AMOTL2,MEX3B,OGA,CHL1,TRAF3IP2,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,NEFM,NF1,SMIM11A,NTRK3,PCDH9,PDE4D,TMOD2,EPB41L4B,PPP2R5E,CEP41,WBP1L,ELOVL2,PTPN13,PTPRD,USP47,OXR1,REV3L,PRRT2,FIGN,SETD5,ALG9,CARF,SEMA6D,SBF1,SCN8A,PPM1E,KIF16B,CPEB3,FNDC3A,FHOD3,NLGN1,FAM81A,WDR47,PKNOX2,TET1,CPEB4,TMCC1,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,TCF4,DMXL2,SATB2,SIRT1,TMEM121,RIMBP2,R3HDM1,PDSS1,TRPS1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30b:PITA hsa-miR-30b:PITA_TOP PITA 3.42E-84 1.92E-80 3.10E-83 2.85E-82 182 863 "ADRA1D,LRFN2,AP2A1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,USP37,PPP4R4,TMEFF1,CADPS,ATP2B2,NRP2,CALB2,SPAG9,USP6,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,ABI3BP,ZNF521,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PLCXD3,FAM131B,DOCK4,MATR3,MAML1,YTHDC1,JAKMIP2,MYEF2,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,EPB41,EPB41L2,STX2,EXTL2,AMOTL2,MEX3B,OGA,CHL1,TRAF3IP2,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,NEFM,NF1,SMIM11A,NTRK3,PCDH9,PDE4D,TMOD2,EPB41L4B,PPP2R5E,CEP41,WBP1L,ELOVL2,PTPN13,PTPRD,USP47,OXR1,REV3L,PRRT2,FIGN,SETD5,ALG9,CARF,SEMA6D,SBF1,SCN8A,PPM1E,KIF16B,CPEB3,FNDC3A,FHOD3,NLGN1,FAM81A,WDR47,PKNOX2,TET1,CPEB4,TMCC1,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,TCF4,DMXL2,SATB2,SIRT1,TMEM121,RIMBP2,R3HDM1,PDSS1,TRPS1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30e:PITA hsa-miR-30e:PITA_TOP PITA 3.42E-84 1.92E-80 3.10E-83 2.85E-82 182 863 "ADRA1D,LRFN2,AP2A1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,USP37,PPP4R4,TMEFF1,CADPS,ATP2B2,NRP2,CALB2,SPAG9,USP6,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,ABI3BP,ZNF521,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PLCXD3,FAM131B,DOCK4,MATR3,MAML1,YTHDC1,JAKMIP2,MYEF2,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,EPB41,EPB41L2,STX2,EXTL2,AMOTL2,MEX3B,OGA,CHL1,TRAF3IP2,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,NEFM,NF1,SMIM11A,NTRK3,PCDH9,PDE4D,TMOD2,EPB41L4B,PPP2R5E,CEP41,WBP1L,ELOVL2,PTPN13,PTPRD,USP47,OXR1,REV3L,PRRT2,FIGN,SETD5,ALG9,CARF,SEMA6D,SBF1,SCN8A,PPM1E,KIF16B,CPEB3,FNDC3A,FHOD3,NLGN1,FAM81A,WDR47,PKNOX2,TET1,CPEB4,TMCC1,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,TCF4,DMXL2,SATB2,SIRT1,TMEM121,RIMBP2,R3HDM1,PDSS1,TRPS1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30c:PITA hsa-miR-30c:PITA_TOP PITA 3.42E-84 1.92E-80 3.10E-83 2.85E-82 182 863 "ADRA1D,LRFN2,AP2A1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,USP37,PPP4R4,TMEFF1,CADPS,ATP2B2,NRP2,CALB2,SPAG9,USP6,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,ABI3BP,ZNF521,SLC35F1,CLOCK,NCOR2,GDA,OSBPL3,PLCXD3,FAM131B,DOCK4,MATR3,MAML1,YTHDC1,JAKMIP2,MYEF2,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,EPB41,EPB41L2,STX2,EXTL2,AMOTL2,MEX3B,OGA,CHL1,TRAF3IP2,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,NEFM,NF1,SMIM11A,NTRK3,PCDH9,PDE4D,TMOD2,EPB41L4B,PPP2R5E,CEP41,WBP1L,ELOVL2,PTPN13,PTPRD,USP47,OXR1,REV3L,PRRT2,FIGN,SETD5,ALG9,CARF,SEMA6D,SBF1,SCN8A,PPM1E,KIF16B,CPEB3,FNDC3A,FHOD3,NLGN1,FAM81A,WDR47,PKNOX2,TET1,CPEB4,TMCC1,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,TCF4,DMXL2,SATB2,SIRT1,TMEM121,RIMBP2,R3HDM1,PDSS1,TRPS1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-let-7c*:mirSVR_lowEffct hsa-let-7c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.32E-84 2.42E-80 3.91E-83 3.60E-82 244 1561 "NCKAP5,KLHL32,PWWP2A,BEND6,INTS2,CASKIN1,KCTD16,TXNDC16,AK2,MARCH4,GPRASP2,PITPNM2,BIN1,APAF1,EPB41L5,UPRT,TNRC6C,LGR5,SHROOM2,CDC14B,PPP4R4,IGDCC4,CASK,RASL11B,TMEM108,SLC4A4,ATP2B2,SLC2A11,N4BP2L1,ST3GAL5,FUBP1,SCAPER,MTMR3,SGCE,THSD7A,CAST,CCNH,CBFA2T2,SEPT7,NUMBL,SRSF11,ASIC3,NDST3,RAB28,NRXN3,CLTC,CNN3,CNTN1,ABI3BP,TOGARAM2,MYRIP,CNRIP1,HINFP,ANKRD44,CSF2RA,SEC24C,SLITRK5,PPP1R16B,PLCXD3,RUBCN,FAM131B,ZFYVE16,MAML1,DGKB,TMEM170A,SPATA2,ELMSAN1,WDR20,DLX1,DRP2,DTNA,EDN1,EDN3,EDNRA,PHC2,RASGRP1,SEMA3D,KLHL5,GOLGA7,STARD3NL,USPL1,GMPR2,FAM198B,DLC1,GORAB,SEC24B,FGF13,SUCO,SCARA3,FOXO3,ATP13A4,EFCAB2,HVCN1,KHDRBS3,CELF1,ST6GALNAC3,CSPG5,MPP6,GABRB3,GALC,ZNF559,C15orf41,ALDH1L1,MSTN,CYP46A1,LYVE1,GLI2,RAB30,ZNF638,DCLK2,PRUNE2,GPR12,PCLO,GRB10,RNF165,IRAK3,PADI2,BACH2,HNF4G,LRRC75A,CELF5,SMAP1,ZNF546,KNDC1,INPP5B,ITPKA,KCND2,KCNN2,KIF5A,IPO5,STXBP5,CYP27C1,KTN1,LIFR,NCOA7,GPR155,MBD1,MOV10,MSI1,MSR1,ZNF862,ALDH1L2,CNOT4,NUCB2,CNTN3,PCDH9,PDE4D,GPR85,PFKFB2,SEMA5B,ZNF655,CCSER2,KCTD15,PDZRN4,STRN3,SCHIP1,ING3,PPP3CA,PRKAB2,MASP1,SAMD9,PTX3,FAT4,RASGRF2,RIC8B,NUDT11,LGI2,C12orf49,CARF,KIRREL1,RORB,RPE,NEK11,BAALC,GLDN,LRRK2,ABCA11P,RTN1,TRAPPC13,DGLUCY,CSRNP3,SEC14L1,FOXRED1,TRA2B,KIF16B,FBXO11,ABLIM3,SIRT2,CDK5RAP3,ATF7IP,CPEB4,SMARCD3,LIMCH1,KIF13A,SNRPN,KDM4B,BDP1,NMNAT2,ZNF423,ZBTB43,RBM26,PBLD,ITPRID2,ZC4H2,LARP4,SS18,SSPO,NXT2,KANK1,JMJD6,VPS13A,ANKRD28,ANKRD12,TBCEL,FBXW11,SATB2,ZEB1,SYNE1,SLC19A3,PCDHB3,GPRIN3,HIF3A,BEX4,PDSS1,RUSC1,SGK3,GORASP1,FLRT2,VLDLR,XPO1,ZBTB14,ZNF24,NDRG4,LYPD6,TCEAL7,CELF4,SPIRE1,CADM2,EVI5,KCNAB1,PDSS2,MSRB3,GAN,ZNF30" MicroRNA hsa-miR-4294:mirSVR_lowEffct hsa-miR-4294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.51E-84 2.52E-80 4.07E-83 3.75E-82 229 1380 "ACADM,CLK4,AS3MT,SYS1,XKR4,ADD1,LRFN2,BEND6,KIAA1324,TAOK1,ALCAM,UNC79,AMT,ZFAT,CDC42BPA,PKP4,CDK10,LINC00173,PCDHGB4,TMEM108,ADAM23,ADAM15,BACH1,MIR9-3HG,CFLAR,SYNJ2,CASTOR3,CA4,CA12,CACNA2D1,KALRN,SPAG9,RUNX1T1,CCPG1,PLEKHB1,EPS15L1,SRP14-AS1,MAP4K4,LY86,CNGA3,TBPL1,AHCTF1,SMARCAL1,TOGARAM2,MYRIP,SLC35F1,ENTPD4,NCOR2,CLIP3,ABCG1,SNCAIP,SEC24C,CSNK1E,VCAN,FAM169A,PITPNM3,PHF14,RUBCN,MYADM,ARMCX2,DGCR5,ZBTB24,SGSM2,NYAP1,RPS6KL1,GOLT1B,E2F5,EDNRB,HEYL,KLHL5,FRY,CELSR3,EGFR,IRAK4,RGS17,TUBD1,EPB41,MFSD10,RASGRP2,DENND4A,ZNF549,CDKL3,FCGRT,ZSCAN30,FER,FGF12,FGFR1,POLK,UBE2E3,SEMA4D,NOP56,FAM49B,CAMKK2,DOT1L,SDCBP2,ZNF44,GALNT15,DENND2A,ZNF234,SULT1C4,CSDC2,GHR,CRCP,GLYR1,GPR12,HMGCR,AGBL5,SHISA6,SMAP1,LRRC25,INPP5B,ITGAM,KCNB1,KCNF1,KCNJ16,GATD1,LIMS1,MAN2A2,MAT2A,AQP11,MEST,KCTD6,MN1,MPP2,MXI1,NDP,NOVA1,DNHD1,OGG1,P2RX7,PCDHGC3,PDCD2,ENPP2,PFKFB2,ZNF655,ZFYVE21,JAKMIP1,SLC25A23,ZNF426,ANKRD16,EPB41L4B,POLG,POU6F1,GRAMD1C,PTPN13,PTPRE,C1orf109,ACSM5,TUG1,ZNF793,NWD1,TRIM68,NUDT11,ALG9,GSTCD,MCMBP,DGLUCY,MAPK12,SEMA6D,SCN2B,SCP2,SEC14L1,GALNT10,SH3GL3,FERMT1,AMBRA1,DZIP1,FAM214B,BTBD7,MAST1,CDK5RAP2,SMARCD3,MBD5,SNRPN,ZSWIM8,KDM4C,PEG10,ARHGAP26,NFASC,NKAIN2,KLHL7,NUDT10,PLCB1,ATMIN,DMXL2,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,GPRIN3,FRYL,CYB561A3,RNF216P1,MTMR14,TMEM9,TRO,PPIL6,TSN,TSC1,TTTY15,TUBB1,RPL7L1,FLRT2,CLDND1,RICTOR,ZNF708,ZNF24,MKRN3,LYPD6,DPYSL5,ANKS1B,SLC17A7,TRIM16L,PCBP4,MPPE1,UBE3B,FBXO36,NLRP3,NETO1,RNF146,FAM198A" MicroRNA hsa-miR-154*:mirSVR_lowEffct hsa-miR-154*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.91E-84 2.75E-80 4.42E-83 4.07E-82 249 1624 "KCNH8,ACADM,SYS1,FMNL2,PSMG3-AS1,ADD2,PLEKHH1,MTUS1,KCTD16,KIAA1324,TAOK1,SPARCL1,ALCAM,AMPD3,DPP10,LRCH2,MAP4K3,PKP4,APAF1,APC,UPRT,NCOA1,NUMB,TMEM108,ATP2A2,ADGRB3,MIR9-3HG,DST,SCAPER,MTMR2,IL33,KALRN,SLC25A14,PRC1,MTMR7,SLC16A4,SEPT7,MAGI1,CDO1,FOXN3,CHN2,B4GALT6,NDST3,RAB33A,CLCN3,C4orf33,QKI,AKAP7,AKAP6,COL4A5,LETMD1,ZNF521,CLOCK,CS,PDE4DIP,SLITRK5,PUM1,ZSCAN23,CCDC144A,GPRASP1,ARHGAP32,RIPOR2,ZNF337,MAML1,HEPH,KIAA0753,DDX46,SNAP91,ZNF582-AS1,CHRDL1,DLX1,GRIN3A,DMTF1,CASP8AP2,ECM2,EDNRB,SEMA3D,FSD1L,OPTN,MBNL2,EGR3,ASB3,EIF4G2,TENM1,EPB41L2,SRRM1,DENND4A,CEP85L,ETV1,CLVS1,NSRP1,FAM198B,ZNF585B,RPS6KC1,FDFT1,SEC24B,FER,MED12L,FGF12,FGF13,UBE2E3,IP6K2,SYNCRIP,FOXO3,TPK1,CAMKK2,ST6GALNAC3,FYB1,ZMAT1,MEGF10,CHL1,GABRG1,GABRG2,C15orf41,DISC1,CPLX2,MMADHC,USP19,GHR,SPIN1,TOX3,KCNMB4,ADGRA3,PRUNE2,GPR12,STON1,STMN2,GRM8,RASSF8,TOX2,HNF4G,NEGR1,AGFG1,NKD1,ZNF678,PAXBP1,NCOA7,MARK1,LRP1B,MEIS2,KITLG,COL28A1,N6AMT1,MXI1,MYCN,NCAM2,NEK1,NF1,CNOT4,NOVA1,NUCB2,CHAMP1,PRTG,ABCB1,NALCN,PIK3C2A,FAM218A,ZFYVE21,GPSM2,PURG,MAPKAP1,SCHIP1,SH3KBP1,DRAM2,PPP2R2C,KANSL1,RANBP3L,PRKCB,GDPD1,RELN,WBP1L,QRICH1,WDR25,CNTLN,PTCH1,PTPRG,PEX2,PPP2R3C,TMEM255A,FAM66C,SH3TC2,RAP1GDS1,KHDRBS2,ERI2,GTDC1,UBR7,RGS4,GSTCD,NEK11,ATP8B4,RPS6KA2,PTGR2,SATB1,CSRNP3,SCP2,FNIP1,KIF21A,CPEB3,AMBRA1,FBXO11,SEC31A,NUBPL,PREX2,SLC8A1,CCDC88A,TET1,CABCOCO1,TMCC1,USP33,DOP1A,BDP1,DOK5,SPP1,ATP10B,THSD1,NKAIN2,CEP68,KLHL7,PLCB1,SYPL1,TBCEL,ZFP90,SLC19A3,NSD1,ZFPM2,SLC44A1,TK2,TPM1,KCNE5,PLEKHH2,VLDLR,XRCC4,PCDH20,ZIC2,UPF3A,DHX33,PRTFDC1,PRDM10,KCNAB1,FIP1L1,FAM47E,FZD3,UBE3B,SMIM8,ACTR3B,RSPRY1,NETO1,RNF146,SOCS4" MicroRNA hsa-miR-2909:mirSVR_lowEffct hsa-miR-2909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.63E-84 3.15E-80 5.06E-83 4.66E-82 194 989 "NDRG2,BRAP,ADRA1D,ZNF608,MTUS1,OSBPL1A,ZNF578,SPARCL1,PCDH10,FGD2,APLP1,UPRT,BCAS1,AQP6,TMEM108,TTLL9,BBS2,MPDZ,C5,RAB29,CALB1,CAMK2G,CAST,CBS,ZBED1,ZMYM4,ARHGAP33,MS4A7,NDST3,LHX2,STOML1,ARMC8,CREM,RBM39,CLIP3,SNCAIP,SUSD5,PDE4DIP,CNTNAP2,KIAA0040,APPL1,PLCXD3,ARHGAP32,LONRF1,PITPNC1,ZNF804A,ZC3H11A,DDX46,DMD,CDON,DPH1,DTNA,ECM2,HIPK3,KLHL5,PHF20L1,APH1A,GOLGA7,EIF4G2,PAN3,EMX2,VPS13B,EPB41,FDFT1,FECH,FER,MED12L,FGF12,AMOTL2,SUCO,SYNCRIP,AGAP3,SLC37A3,NOP56,C2orf88,TMEM107,UFM1,PDLIM5,ATP2C1,STAU2,HHIPL1,ABLIM2,OGA,ZMAT1,HRASLS5,CHL1,GALNT15,CSDC2,GHR,GNAO1,GPT2,AP4S1,SLC2A6,HAS2,ELOVL5,MSL1,IDH3B,ZIC5,JAK2,LIFR,HECTD2,NCOA7,PACRG,KCTD6,XRRA1,ZNF680,SFR1,NTRK2,OGG1,PCDH8,PCSK5,ZNF655,CCSER2,KCTD15,FAM216A,PLCD1,SLC25A23,MTRF1L,STRN3,PSAT1,ING3,SH3KBP1,RANBP3L,PTPRE,MARCH1,USP47,RADX,KHDRBS2,PBRM1,DCUN1D2,ALG9,CARF,PCMTD2,SPIN3,LRRK2,KCNIP3,ZNF331,AP1AR,PRCD,COPZ1,FERMT1,FBXO11,WDR37,SLC14A1,ZKSCAN3,SMARCC2,RCOR3,SP4,ZC3H13,SPTAN1,CDK19,LMO3,CLASP2,CLSTN2,SAMSN1,ZC4H2,VPS13A,SYN1,SYN2,TACR1,SATB2,TRIM2,CLASP1,PHF24,USP32P1,PCDHA5,FAM200B,ZFPM2,AKTIP,GALNT17,TIAM1,ERCC6L2,TMPO,RASD2,TPM1,NPL,TRIO,STXBP4,EIF4ENIF1,LINC00689,UGT8,BCL2L13,VSNL1,RICTOR,GUSBP1,TCEAL7,SPIRE1,EMSY,NAV3,FAM13C,DOCK8,UBE3B,KLHDC1,ST8SIA2" MicroRNA hsa-miR-181d:PITA hsa-miR-181d:PITA_TOP PITA 5.85E-84 3.27E-80 5.25E-83 4.83E-82 177 816 "KCNH8,FMNL2,TMEM132B,CCDC85A,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,CDC14B,SEMA4G,MADD,SLC4A4,ATP2B2,RNF182,ADGRB3,JAZF1,WASF1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,QKI,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,LONRF1,ELMSAN1,MFAP3L,ZC3H11A,POM121,SPOCK3,MTX3,WDR20,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,E2F5,KLHL5,FSD1L,MBNL2,EGR3,PAN3,NCALD,CLVS1,DLC1,MEX3B,PCYOX1,SYT3,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GRB10,GRIA2,CIT,ADAMTS6,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,IPO5,LIFR,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,HS6ST3,NEXMIF,ZC3H12B,NEFH,CNOT4,NOVA1,IGSF11,GPR137C,PCSK1,PRTG,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,PPARA,PPP2R5E,CEP41,CNNM2,PTPRE,USP47,FIGN,RFX2,PRIMA1,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,FNIP1,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,TMCC1,FAM126B,DOP1A,NMNAT2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,PRRC2C,MTCL1,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,SLC35G2,SIRT1,TNS1,NR2C2,ZIC2,ZNF28,SMARCAD1,SEMA3B,PHTF2,SOCS4" MicroRNA hsa-miR-181b:PITA hsa-miR-181b:PITA_TOP PITA 5.85E-84 3.27E-80 5.25E-83 4.83E-82 177 816 "KCNH8,FMNL2,TMEM132B,CCDC85A,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,CDC14B,SEMA4G,MADD,SLC4A4,ATP2B2,RNF182,ADGRB3,JAZF1,WASF1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,QKI,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,LONRF1,ELMSAN1,MFAP3L,ZC3H11A,POM121,SPOCK3,MTX3,WDR20,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,E2F5,KLHL5,FSD1L,MBNL2,EGR3,PAN3,NCALD,CLVS1,DLC1,MEX3B,PCYOX1,SYT3,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GRB10,GRIA2,CIT,ADAMTS6,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,IPO5,LIFR,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,HS6ST3,NEXMIF,ZC3H12B,NEFH,CNOT4,NOVA1,IGSF11,GPR137C,PCSK1,PRTG,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,PPARA,PPP2R5E,CEP41,CNNM2,PTPRE,USP47,FIGN,RFX2,PRIMA1,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,FNIP1,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,TMCC1,FAM126B,DOP1A,NMNAT2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,PRRC2C,MTCL1,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,SLC35G2,SIRT1,TNS1,NR2C2,ZIC2,ZNF28,SMARCAD1,SEMA3B,PHTF2,SOCS4" MicroRNA hsa-miR-944:PITA hsa-miR-944:PITA_TOP PITA 6.12E-84 3.43E-80 5.48E-83 5.05E-82 191 958 "RALGAPA1,KLHL32,AXIN2,USP31,PTCHD1,ZNF608,INTS2,HECW2,HFM1,SEMA6A,SPOP,FAM135A,LRCH2,MAP4K3,APBB2,APC,CDC14B,TMEFF1,CDK13,STK33,NCOA1,ATP2B2,CACNB4,KALRN,CAMK2G,RUNX1T1,USP6,SCARB1,LRBA,DCLK1,MAGI1,CDO1,CFL2,FOXN3,LHX2,QKI,AKAP6,AKAP5,TBPL1,AHCTF1,SLC35F1,SUSD5,DZIP3,PPP1R16B,APPL1,PNPLA8,ZFYVE16,PABPC5,MYEF2,TIAM2,ZC3H11A,SV2B,RAB39B,DMD,USP3,CPEB2,CASP8AP2,DPYSL2,DNAJB6,CNNM1,YAF2,MBNL2,KMT5B,EIF4G2,TENM1,RGS17,PAN3,EMX2,SRRM1,EYA1,NRN1,ACSL4,JKAMP,FUT9,MEGF10,ERAP1,SRRM4,GATM,MSTN,ARFIP1,SESN1,PCDH17,GHR,PPARGC1A,SPIN1,DCLK2,GRIA2,LINGO1,ZHX1,FRMD5,MIER3,GABARAPL2,HNF4G,NEGR1,ICA1,NKD1,KCND2,KTN1,SMAD1,GPR155,MATN3,CHIC1,LRP1B,MID1,MITF,MKLN1,MXI1,ZC3H12B,NEFM,NF1,NOVA1,PDPK1,PMP22,TRHDE,RETREG2,EPB41L4B,LRRN3,PPP3CA,PRKAB2,PKIA,CNTLN,PTCH1,TMEM260,ZSCAN32,PTPRB,PTPRO,PTX3,SH3TC2,OXR1,RADX,KHDRBS2,FIGN,ZFHX4,SETD5,ZC3H14,MCMBP,HUNK,CLIP1,RTN1,SATB1,SCAF8,KIF16B,CPEB3,CHD9,ST6GAL1,NLGN1,SEPHS1,CCDC88A,SLC12A2,CPEB4,TRERF1,SOX11,SP4,PEG10,CDK19,LARP4,ERBIN,STXBP1,PLCB1,SIN3B,TRIM2,RPGRIP1L,DICER1,ZFPM2,AP4E1,SLC44A1,CSMD1,TRPS1,SSBP2,HIRA,FAM155A,TBC1D15,MICU3,KCNT2,MKRN3,LYPD6,ZBTB38,TMEM237,ZFAND5,SLC38A1,PRDM8,NAV3,PDSS2,FZD3,PHTF2,JMJD1C,MSRB3,NETO2,SOCS4,ST8SIA2,SENP7" MicroRNA hsa-miR-513a-3p:PITA hsa-miR-513a-3p:PITA_TOP PITA 7.15E-84 4.00E-80 6.39E-83 5.88E-82 173 778 "ESYT2,KLHL13,PCDH19,TAOK1,SPOP,ALCAM,FAM135A,DPP10,LRCH2,PKP4,NCOA1,DYNLL1,STX16,FUBP1,MTMR3,LDLRAD4,KALRN,ZMYM4,CCPG1,CFL2,FOXN3,SOCS6,CNOT8,QKI,SULT4A1,CNN3,IQCK,CREM,GDA,LRIG1,LRRC3B,CNTNAP2,SLITRK5,DOCK4,LONRF1,MATR3,SNAP91,MTX3,WDR20,DLX1,DPYSL2,ARRDC4,SNX29,KMT5B,EIF4G1,TMEM35A,PTK2B,HPCAL4,PSD2,AFF2,NBEA,FUT9,ZMAT1,MSTN,AHDC1,PCDH17,PPARGC1A,DBF4,TNRC6A,ZNF638,FERMT2,GPT2,GPR34,ZBTB49,ZHX1,BACH2,AGFG1,ZIC5,TJAP1,CREG2,IPO5,SMAD1,MAP2,MAP4,MARK1,MEIS1,KITLG,MITF,AFF1,MXI1,MYCN,NEXMIF,NACA,NEFM,NEK1,NELL2,NFIX,NOVA1,NPTX2,NRCAM,CHAMP1,PCDH8,PCSK1,PDE4D,PFKFB3,PIK3C2A,XRN1,PLCL1,LRP12,SH3KBP1,DRAM2,MINDY2,PPP3CA,KANSL1,RELN,VPS13C,SNRK,PTPRD,SUSD4,OXR1,RBBP6,NUDT11,PBRM1,ZFHX4,FBXW7,SEMA6D,PPM1E,CPEB3,NLGN1,FAM81A,PPP4R3A,SNCA,MYCBP2,SPP1,KDM4C,ZBTB43,POGZ,LARP4,NKAIN2,ERBIN,CEP68,TTBK2,STX1A,ARHGEF9,SYN2,SYPL1,CAMTA1,TAL1,AGTPBP1,FBXW11,ATMIN,TCF4,SATB2,ZEB1,TRIM2,RPGRIP1L,TCF12,PUM2,DICER1,SLC44A1,HEY1,RUNDC3B,TRPS1,HIRA,FAM155A,USP1,BCL2L13,CLDND1,XPO1,ZNF711,ZFAND5,SMARCAD1,SLC30A4,RNF103,FIP1L1,WNK3,RGS7BP,FAM13C,FZD3,KAT6A,SNX14,RNF146,CPNE4" MicroRNA hsa-miR-548e:PITA hsa-miR-548e:PITA_TOP PITA 7.44E-84 4.16E-80 6.64E-83 6.11E-82 178 827 "KCNH8,FMNL2,CCDC85A,USP31,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,AMPH,CDC42BPA,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,SLC4A4,ADGRB3,SYNJ1,ARHGEF7,FUBP1,WASF1,CACNB4,CALB1,CALM1,PTBP2,RUNX1T1,SEPT7,CLGN,NOG,SRSF11,SOCS6,LHX2,CLTC,FAM19A5,QKI,BAG4,CLOCK,CDC42BPB,CREM,CRMP1,ERC2,PLCXD3,HDAC4,LONRF1,MATR3,DGKB,MYEF2,ZC3H11A,DDX46,FAM107B,DMD,USP3,HIPK3,KMT5B,EIF4G2,STARD3NL,EIF1,TAOK3,FGF13,FGFR3,SUCO,FOXO3,FAM49B,GABRB3,GABRG2,MSTN,AHDC1,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,SOX21,PSIP1,BACH2,MIER3,HLF,NEGR1,SMAP1,KIF2A,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,TTC13,PID1,CEP97,RBBP8,RADX,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,SOX11,SOX15,LMO3,CLASP2,SS18,ERBIN,ST5,RGL1,PLCB1,ANKRD12,CAMTA1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,TMEM121,ZFPM2,SLC44A1,TLR4,ERCC6L2,KCNE5,TUBB2A,RPRM,FLRT2,WIPF1,ZBTB14,ZNF711,ZFAND5,SMARCAD1,EMSY,STOX2,NAV3,KCNAB1,PCBP4,WNK3,PDSS2,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-346:mirSVR_lowEffct hsa-miR-346:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.53E-84 4.77E-80 7.60E-83 7.00E-82 208 1143 "GALNT16,BRAP,PTCHD1,SLC24A4,ZNF608,HACE1,TXNDC16,CARNS1,PDZD4,AMT,CCDC146,PPFIA4,PHF12,EPB41L5,BCAS1,ARNTL,ARRB1,MYOM1,KSR1,SYNJ2,FUBP1,SCAPER,CABP7,PTBP2,VXN,RGN,LRRFIP1,CHGB,MS4A7,RAB28,SLC4A8,CRHBP,NCOR1,CLIP3,SEC24C,ARHGEF10,VCAN,PPP1R16B,RUBCN,FAM131B,CYBB,RASSF2,INTS1,DGKG,DAPK1,HEPH,LYPD1,RHOBTB1,SLC29A4,CPEB2,DMTF1,DTNA,ECM2,E2F5,WDPCP,ANKRD46,HIPK3,CNNM1,PHF20L1,MRO,MBNL2,TENM1,DCTN4,EPHB1,DENND4A,NCALD,MRPL37,EYA1,MRVI1,F5,RACK1,FCGRT,GORAB,FER,SPSB4,FGF14,BAIAP2,SUCO,AGAP3,CINP,UFM1,ZNF605,KHDRBS3,CGREF1,NSG1,GABRG1,DISC1,INPP5K,SESN1,ADAM28,GHR,HPGDS,TOX3,ZNF638,WDFY3-AS2,ADGRA3,PRRC2B,GPD2,STMN2,CLASRP,RNF165,GSTM5,RABL2A,ADAMTS6,ZDHHC15,FAM95B1,LRRCC1,FAM69A,CDH20,KIF5A,CAMK2N2,STMN1,LIG4,MAP6,TM6SF1,MEIS1,DBNL,NME4,NUCB2,SETD4,IGSF11,PDE4A,PDE4D,PDPK1,PFKFB3,JAKMIP1,PMP22,SCHIP1,ING3,CCDC144B,PRKAB2,GRAMD1C,MASP1,QRICH1,PIGG,BDNF-AS,PTN,STK32A,PTPN13,EML5,USP47,SUSD4,RET,SLC25A36,PBRM1,CARF,RORB,ARMH4,SPIN3,ZNF671,ATP8B4,MEG3,ABCA11P,NCBP3,ST6GAL1,FAM81A,PKNOX2,SLC6A8,CPEB4,ZFP1,LIMCH1,SNRPN,HECW1,SPART,NFASC,MESP1,SEPT8,ARHGEF9,NUDT10,ADAMTS17,ANKRD12,TAL1,ADGRL3,KLHL4,TCF4,NEU4,FRYL,DICER1-AS1,CHST8,ZMAT3,AKTIP,CDH22,ERCC6L2,CSMD1,NPL,C9orf85,ZNF346,PPIL6,DCBLD1,UBE2H,UBTF,MTCH1,LAT2,LGI4,ZIC1,AGMO,POLR3H,MEIS3,INTS3,SLC38A1,VPS35L,NAV3,URM1,FAM47E,PCBP4,DOCK8,TMEM63C,IFT88" MicroRNA hsa-miR-374b*:mirSVR_highEffct hsa-miR-374b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.76E-84 5.46E-80 8.68E-83 7.99E-82 194 992 "ACADM,CLK4,BRAP,KCTD16,TAOK1,ARHGAP20,PCDH10,APC,CDK13,STK33,STX16,BACH1,MPDZ,KSR1,SYNJ1,NAE1,JAZF1,KALRN,PTBP2,VXN,CAST,CH25H,SPAG9,SEPT7,LOC730101,MAGI1,CDO1,QKI,HECTD1,MAP4K4,RCHY1,COX4I1,TOGARAM2,MYRIP,ANKRD44,CS,SEC24C,LRIG1,ARHGEF10,SOCS5,FAM169A,APPL1,RUBCN,HDAC9,TCAF1,KIAA0586,IST1,TMEM170A,PABPC5,PITPNC1,MYEF2,PLPPR4,CPEB2,DTNA,DNM1L,GOLT1B,AASDH,EDNRB,YAF2,PHF20L1,RACK1,FCGRT,ZSCAN30,FER,FGFR1,POLK,FLT1,COQ5,SMC2,UFM1,MPP6,FYB1,GABRB3,DENND2A,FAM120B,RAPGEF6,ALDH1L1,TUBGCP4,PCDH17,PPARGC1A,SPIN1,RAB30,MSL3,GNAL,FERMT2,ADGRA3,GPD2,LPAR4,DIDO1,ARHGAP36,AGBL5,ZDHHC15,MSL1,LRRCC1,SCIN,SLC35G1,KCNN2,KIF2A,KIF5A,NCOA7,PACRG,MARK3,MATN2,MATN3,MBNL1,MOV10,ADAM22,NDP,NFE2L2,CHAMP1,OGG1,PAX6,PFKFB2,NALCN,CCSER2,ZFYVE21,XRN1,PLIN1,PURG,LRP12,ING3,PPM1B,PPP2R5E,PPP3CA,RASGEF1B,SNRK,CNTLN,TMEM260,PTPRD,PTPRE,TMEM255A,RAD17,RASGRF1,UBR7,PBRM1,RNASEL,TMLHE,GSTCD,ROBO1,FBXW7,BAALC,ZC3H14,GLDN,AP1AR,SALL1,SATB1,ATXN2,PEAR1,ZFP30,KIF21A,KIF16B,SHC4,CHD9,ANKRD6,FAM81A,PREX2,CCDC88A,SLC12A2,GKAP1,RBM34,KDM3A,ZC3H13,DBNDD2,POGZ,KANK1,SYNE2,VPS13A,CAMTA1,ADGRL3,PCDHB9,PUM2,ZFPM2,AP4E1,ERCC6L2,CHST5,RUNDC3B,STXBP4,RUSC1,FLRT2,VLDLR,VSNL1,WIPF1,WNT7A,TRIM9,CELF4,ZBTB38,FSTL5,SMARCAD1,EMSY,CADM2,SLC38A1,STOX2,TTC7A,CPNE4" MicroRNA hsa-miR-4261:mirSVR_highEffct hsa-miR-4261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-83 5.66E-80 8.98E-83 8.26E-82 250 1642 "RALGAPA1,KCNH8,EMILIN3,NCKAP5,FMNL2,ADCY6,BRAP,PLEKHH1,MTA3,PCDH19,ADGRF5,SPOP,ABCD2,UNC79,FAM135A,OGT,ANK2,SMIM29,APLP1,USP37,ARNTL,ASPA,BCHE,GPR146,SYNJ1,FUBP1,CACNA1G,DDR1,CACNB4,CALB1,KALRN,VXN,CAST,HIP1R,USP6,MAGI1,B4GALT6,RAB33A,NRXN3,ABCG2,CNR1,CNTN1,PCYT1B,ARMC8,SUMF2,SLC4A8,CNRIP1,FAM171B,CLOCK,CRMP1,HAPLN1,ANKRD44,GDA,TRIM69,CS,SNCAIP,CSNK1E,FAM169A,DZIP3,PHF14,CCDC144A,DOCK4,HDAC9,RIPOR2,DAPK1,SCRN1,JAKMIP2,FBXL5,RHOBTB1,WDR20,EXOG,EDIL3,SNX29,EDNRA,EDNRB,TMTC1,FSD1L,CELSR3,FAM13A,PHF20L1,SUGP2,MBNL2,KMT5B,AASS,COPS4,TMEM35A,STARD3NL,EPHB1,RACK1,FDFT1,GORAB,SPSB4,FGF12,BAIAP2,PRKAG2,SEC23B,PCYOX1,AGAP2,SYNCRIP,IQCG,ANKFY1,SMC2,SPECC1,PDLIM5,TPK1,KHDRBS3,STAU2,MSANTD4,GALNT15,GALC,SESN1,GFER,GGT7,CRCP,DBF4,KDM2B,GNAL,ADGRA3,PRRC2B,PRUNE2,GPR12,PCLO,GRIA2,DIDO1,ADAMTS13,ZNF496,RABL2A,ADAMTS6,ZHX1,GABARAPL2,NEGR1,IRF8,ITPKB,LAMP2,SYTL4,SMAD1,PIK3AP1,MAP4,MAT2A,MBD1,MEIS1,SRSF12,MIA2,MSI1,MX1,SFR1,NF1,SLC11A2,NTRK2,IGSF11,CHAMP1,GLIPR1L2,CNTN3,PCSK1,PDE3A,PDE4D,PLIN1,ANKRD16,MAPKAP1,EPB41L4B,FA2H,POLR2F,TATDN3,KANSL1,RASGEF1B,PRKACB,CEP41,PKIA,EPDR1,VPS13C,GDPD2,CNTLN,TMEM260,ZIK1,ZSCAN2,SH3TC2,ENOX1,RASGRF1,RASGRF2,MSANTD2,SLC25A36,PBRM1,CARF,ROBO2,CCDC25,ELP2,TCP11L1,MEG3,ABCA11P,KCNIP1,SAFB,ATXN7,LRFN5,SCP2,FERMT1,SHC4,CHD9,FHOD3,SYBU,ABLIM3,FAM81A,SLC2A5,TET1,EPC1,ZFP1,SMARCD3,MBD5,TMCC1,SP4,GLT8D1,RBM26,ATP10B,CLASP2,POGZ,SSTR1,SSTR2,LARP4,SEPT8,RGL1,ADHFE1,NECAB1,NUDT10,SYPL1,FBXW11,SMG6,ZEB1,GPRIN3,ZFPM2,AP4E1,ACTR6,TMPO,TSC1,PLEKHH2,MICU3,TRIM9,ZNF540,AGMO,NDRG4,ZSCAN26,SLC30A4,RNF103,NAV3,MPPE1,PLSCR4,FZD3,KAT6A,HNRNPA3,ADAMTSL3,NETO1,DPF3" MicroRNA hsa-miR-571:mirSVR_lowEffct hsa-miR-571:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-83 7.57E-80 1.20E-82 1.10E-81 226 1352 "RALGAPA1,KCNH8,ABR,EMILIN3,NCKAP5,XKR4,TMCC3,ADD1,BRAP,PLEKHH1,PTCHD1,ADRA1D,FAHD2CP,DPY19L2P4,MTUS1,KLHL13,PCDH19,TAOK1,PCDH10,FAM135A,ZNF687,AMPH,LRFN1,DPP10,UPRT,BCAS1,TNRC6C,PPFIA3,CDK13,TMEM108,MYOM1,RGS9,BMPR1B,CASTOR3,CALB1,CALM1,HAP1,CAST,LDB2,CCNH,UBE2L6,CFL2,ASIC3,EPS15L1,RAB33A,NRXN3,AKAP6,LETMD1,SMARCAL1,CRMP1,CLIP3,SNCAIP,CSF1R,LRRC3B,GALNT9,CNTNAP2,CST3,PHF14,PPP6R2,FAM131B,ARHGAP32,TCAF1,EARS2,KCTD8,DGKB,SCRN1,DNAL1,ARMCX4,WDR20,CHRDL1,GRIN3A,USP3,CD99L2,DTNA,MAMLD1,DNM1L,GOLT1B,E2F6,FCF1,HEYL,CELSR3,PHF20L1,AASS,TUBD1,EPB41,SIRPB1,MRVI1,CHST15,FDFT1,SEC24B,GTF2IRD2,FHL1,RGPD5,FLT1,CAMKK2,NSG1,GABRA3,GAD1,ALDH1L1,GGT7,MSL3,GLUL,AIFM3,FERMT2,ADGRA3,LPAR4,PCLO,CIT,RNFT2,ADAMTS6,SLC2A6,FAM222A,PADI2,FRMD3,ZDHHC15,SHISA6,IGF1,KNDC1,KHK,KIT,MAP2,MAP6,MARK1,MBD1,MEIS1,KITLG,GIT1,N6AMT1,HS6ST3,P2RY13,NEK1,NF1,CNOT4,NOVA2,CNTN3,PCSK1,PDE4B,PFKFB3,ZNF655,PMP22,POLG,PCDHB17P,PRKAB2,MAPK4,BCAS3,WBP1L,EML5,PTPRE,PTPRG,FAT4,FAM184A,RASGRF2,ZDHHC14,MSANTD2,RIC8B,CARF,NEK11,ARMH4,STK32B,ABCA11P,AP1AR,DGLUCY,MAPK12,SCP2,ZFP2,GALNT10,ZFP30,SH3GL3,ARX,AMBRA1,FBXO11,WDR37,ABLIM3,FAM214B,SEPHS1,CCDC88A,SLC11A1,EPC1,LIMCH1,DOP1A,SP2,NMNAT2,PEG10,IQSEC2,DDN,CLSTN2,ITPRID2,SAMSN1,SS18,ERBIN,ELOVL4,SEPT8,SYNE2,TMEM150C,SYN2,SYP,IQCE,TBL1X,ZFP90,CUX2,SZT2,SYNE1,USP32P1,SIK3,DICER1-AS1,THRA,ICAM5,R3HDM1,NPL,RGMB,SYNPO2,TRIO,PDSS1,UBE3A,XRCC4,ZNF138,ZNF177,DPYSL5,FTSJ1,DNALI1,MPPE1,WNK3,ST7,KAT6A,RNF170,NETO1" MicroRNA hsa-miR-181b-5p:TargetScan hsa-miR-181b-5p TargetScan 1.72E-83 9.61E-80 1.51E-82 1.39E-81 192 974 "ASIC1,NDRG2,FMNL2,GALNT16,CCDC85A,BRAP,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,C6orf89,GAS7,MADD,ATP2A2,ATP2B2,RNF182,HCN2,KSR1,JAZF1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,QKI,MAP4K4,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,DNAL1,ELMSAN1,MFAP3L,KLHL3,MTX3,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELN,PAN3,EMX2,EPB41,NCALD,CLVS1,SCML2,MED12L,FGFR3,MEX3B,FLT1,ANKFY1,NBEA,NSG1,IQGAP2,GCNT2,RAB30,GNAO1,GPD2,GRB10,GRIA2,FAM19A2,KAT7,RASSF8,BACH2,MIER3,HLF,NEGR1,AGFG1,IL6ST,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,NOVA1,IGSF11,GPR137C,PCSK1,PDE3A,PDPK1,GNG2,PIK3C2A,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,PTGR2,CLIP1,AP1AR,CSRNP3,ATXN7,FAM102A,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,DIP2A,KANK1,PRRC2C,ATMIN,DMXL2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,NR2C2,KCNK12,NDRG4,PHTF2,RNF146" MicroRNA hsa-miR-181d-5p:TargetScan hsa-miR-181d-5p TargetScan 1.72E-83 9.61E-80 1.51E-82 1.39E-81 192 974 "ASIC1,NDRG2,FMNL2,GALNT16,CCDC85A,BRAP,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,C6orf89,GAS7,MADD,ATP2A2,ATP2B2,RNF182,HCN2,KSR1,JAZF1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,QKI,MAP4K4,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,DNAL1,ELMSAN1,MFAP3L,KLHL3,MTX3,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELN,PAN3,EMX2,EPB41,NCALD,CLVS1,SCML2,MED12L,FGFR3,MEX3B,FLT1,ANKFY1,NBEA,NSG1,IQGAP2,GCNT2,RAB30,GNAO1,GPD2,GRB10,GRIA2,FAM19A2,KAT7,RASSF8,BACH2,MIER3,HLF,NEGR1,AGFG1,IL6ST,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,NOVA1,IGSF11,GPR137C,PCSK1,PDE3A,PDPK1,GNG2,PIK3C2A,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,PTGR2,CLIP1,AP1AR,CSRNP3,ATXN7,FAM102A,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,DIP2A,KANK1,PRRC2C,ATMIN,DMXL2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,NR2C2,KCNK12,NDRG4,PHTF2,RNF146" MicroRNA hsa-miR-181a-5p:TargetScan hsa-miR-181a-5p TargetScan 1.72E-83 9.61E-80 1.51E-82 1.39E-81 192 974 "ASIC1,NDRG2,FMNL2,GALNT16,CCDC85A,BRAP,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,C6orf89,GAS7,MADD,ATP2A2,ATP2B2,RNF182,HCN2,KSR1,JAZF1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,QKI,MAP4K4,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,DNAL1,ELMSAN1,MFAP3L,KLHL3,MTX3,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELN,PAN3,EMX2,EPB41,NCALD,CLVS1,SCML2,MED12L,FGFR3,MEX3B,FLT1,ANKFY1,NBEA,NSG1,IQGAP2,GCNT2,RAB30,GNAO1,GPD2,GRB10,GRIA2,FAM19A2,KAT7,RASSF8,BACH2,MIER3,HLF,NEGR1,AGFG1,IL6ST,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,NOVA1,IGSF11,GPR137C,PCSK1,PDE3A,PDPK1,GNG2,PIK3C2A,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,PTGR2,CLIP1,AP1AR,CSRNP3,ATXN7,FAM102A,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,DIP2A,KANK1,PRRC2C,ATMIN,DMXL2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,NR2C2,KCNK12,NDRG4,PHTF2,RNF146" MicroRNA hsa-miR-181c-5p:TargetScan hsa-miR-181c-5p TargetScan 1.72E-83 9.61E-80 1.51E-82 1.39E-81 192 974 "ASIC1,NDRG2,FMNL2,GALNT16,CCDC85A,BRAP,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,C6orf89,GAS7,MADD,ATP2A2,ATP2B2,RNF182,HCN2,KSR1,JAZF1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,QKI,MAP4K4,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PLCXD3,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,DNAL1,ELMSAN1,MFAP3L,KLHL3,MTX3,NR1D2,CDON,DPP6,DPYSL2,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELN,PAN3,EMX2,EPB41,NCALD,CLVS1,SCML2,MED12L,FGFR3,MEX3B,FLT1,ANKFY1,NBEA,NSG1,IQGAP2,GCNT2,RAB30,GNAO1,GPD2,GRB10,GRIA2,FAM19A2,KAT7,RASSF8,BACH2,MIER3,HLF,NEGR1,AGFG1,IL6ST,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,NOVA1,IGSF11,GPR137C,PCSK1,PDE3A,PDPK1,GNG2,PIK3C2A,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,PTGR2,CLIP1,AP1AR,CSRNP3,ATXN7,FAM102A,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,LARP4,NKAIN2,DIP2A,KANK1,PRRC2C,ATMIN,DMXL2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,NR2C2,KCNK12,NDRG4,PHTF2,RNF146" MicroRNA hsa-miR-15b*:mirSVR_highEffct hsa-miR-15b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-83 1.11E-79 1.75E-82 1.61E-81 234 1450 "KCNH8,ABHD6,NCKAP5,XKR4,KLHL32,AP2A2,CEP126,OGT,PHF12,BCAS1,CASK,RGS20,SLC4A4,SEC11C,RAB29,WASF1,CA8,KALRN,PTBP2,CBR1,KRIT1,LRBA,L3MBTL4,MAGI1,CLGN,CHN2,PLAA,C4orf33,LETMD1,ABI3BP,FAM171B,CLOCK,C2CD2,GDA,ABCG1,SEC24C,ARHGEF10,PDE4DIP,GREB1,DOCK4,PABPC5,PITPNC1,MFAP3L,FBXL5,C2CD2L,SPOCK3,GRIN3A,DMD,PDCD6IP,FAM78B,DNM1L,GOLT1B,E2F5,EDNRA,ANKRD46,FAM13A,ASB3,STARD3NL,DCTN4,EPB41L2,ETV1,TLR7,SIRPB1,F5,CLVS1,RPS6KC1,TMEM132C,ACSL4,CEP78,FER,GTF2IRD2,FGF11,POLK,SMC2,UFM1,TPK1,CAMKK2,KHDRBS3,CELF1,ST6GALNAC3,CHL1,ERAP1,DISC1,KIAA1841,SESN1,ADAM28,PPARGC1A,MALT1,ZNF276,COPS8,DBF4,RAB30,GNAL,LNX1,TDRKH,FUT10,CIT,AP4S1,RNFT2,RASSF8,HLF,HNF4G,ZDHHC15,SHISA6,IRF8,ZNF546,SCIN,ZNF678,SLC35G1,KCNN1,PAXBP1,PIK3AP1,MAP4,MAT2A,MBNL1,MEIS1,MIA2,KITLG,NCAM2,NF1,CNOT4,CHAMP1,OPA1,LOC100128398,GPR137C,PRTG,NALCN,PIK3R1,CCSER2,ZFYVE21,SCHIP1,EPB41L4B,SH3KBP1,C19orf57,DRAM2,PPM1B,PPP2R5E,PKIA,HYDIN,DCHS2,SNRK,CNTLN,BDNF-AS,TMEM260,STK32A,PTPRG,PPP2R3C,PID1,FAM66C,ENOX1,OXR1,RASGRF2,ERI2,GTDC1,RFX3,UBR7,SLC25A36,PBRM1,RNASEL,CCDC82,TMLHE,CARF,PNMA8A,GSTCD,CCDC102B,LRRK2,PTGR2,RTN1,ZNF568,ZNF331,CSRNP3,SEC14L1,MRAS,COPZ1,ZFP30,CHD9,ST6GAL1,WDR37,SLA,PPP4R3A,CDK5RAP2,SNCA,TRERF1,HECW1,KDM4C,SS18,RGL1,NECAB1,PRRC2C,NUDT10,SYP,COBL,ADGRL3,TBCEL,ATMIN,TRIM2,RPGRIP1L,PCDHGA11,PCDHB10,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,ITGB3BP,AP4E1,AKTIP,HEY1,TMPO,RIMBP2,KCNE5,USP1,VLDLR,WIPF1,GUSBP1,XRCC4,ZNF19,ZNF70,ZNF138,FSTL5,ZNF189,ANKS1B,EMSY,MFF,PRTFDC1,ADAMTS9,TRIM16L,PHTF2,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-3199:mirSVR_lowEffct hsa-miR-3199:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.99E-83 1.12E-79 1.75E-82 1.61E-81 231 1414 "SYS1,ADCY6,RNF157,ADD1,PLEKHH1,ADORA2A,MTA3,PCDH19,UNC79,AMPD3,LRFN1,ZFAT,EP400,PPFIA4,PKP4,VAT1L,PPFIA3,SFMBT2,SEMA4G,IGDCC4,PDE8B,ATP1A3,ADAM15,CFLAR,KSR1,GPC2,CA4,PTBP2,SPAG9,P2RX6,ARHGEF1,SYNGR3,ENTPD6,DGKI,NOG,NPIPA1,ASIC3,CHN2,PLEKHB1,PPT2,TPP1,IQCK,WHRN,SUMF2,IGDCC3,RBM39,CRMP1,CRY2,ANKRD44,CRYM,CS,VCAN,PDE4DIP,ERC2,RUBCN,BOC,KATNAL2,SNPH,ZFYVE16,DAPK1,SCRN1,AIF1L,DNAL1,ZBTB24,DDX46,SGSM2,FAM107B,EXOG,DRP2,DTNA,AASDH,CNNM1,HEYL,TMTC1,TNK2,MRNIP,ELN,DCTN4,EMX2,ABCA8,TAOK3,CEP78,SPSB4,HPCAL4,IP6K2,TMEM175,ERGIC3,KHDRBS3,ABLIM2,TVP23A,MEGF11,GABRG1,DISC1,GPR162,GFER,AIFM3,LOXL3,WDFY3-AS2,TDRKH,STON1,GRB10,GRIN2D,CIT,BTN2A1,KAT7,GSTT2,FAM222A,EID2B,ZNF546,LRRC25,DISP2,IL6ST,SLC6A17,KCNK3,KIT,NCOA7,MAP2,TM6SF1,MEIS1,KITLG,SCAMP5,MXI1,CCDC13,NTRK2,LOC100128398,GPR137C,PCSK1,DUSP26,KCTD15,NLE1,PLCD1,FXYD1,SMIM7,PLTP,PNMA3,PPP2R5E,KANSL1,NKAIN4,PSD,ANKHD1,ZSCAN32,CASTOR1,ACSM5,TTC13,TMEM255A,CCDC40,RASGRF2,HKR1,RDX,RET,RNASEL,LGI2,C12orf49,KIRREL1,FBXW7,ZNF671,TCP11L1,STK32B,LRRK2,MEG3,HSD11B1L,KCNIP3,RYR3,PRCD,SEC14L1,FAM102A,PPM1E,ASAP3,FBXO11,ST6GAL1,SLA,FAM214B,KANSL3,RADIL,SLC11A1,SLC22A4,ABTB1,INTS9,MBD5,SNRPN,MYO16,KDM4B,DOP1A,TRERF1,KDM4C,PEG10,ZC3H13,ATP10B,POGZ,ZC4H2,ZSCAN29,ADHFE1,STX1A,STXBP1,SYN1,TAL1,SMG6,SZT2,PHF24,FAM189A1,USP32P1,RNF216P1,TEK,ZFPM2,ITGB3BP,GALNT17,TMEM9,BEX4,PIK3R5,RGMB,ZNF346,TRO,PPIL6,TTTY15,HSPBP1,ZKSCAN5,HIRA,PLPPR2,CCDC136,LAT2,TRIM9,NDRG4,LYPD6,ZNF138,PRTFDC1,GAL3ST3,FZD3,KAT6A,CASC15,ST8SIA2,SENP7" MicroRNA hsa-miR-190b:mirSVR_highEffct hsa-miR-190b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.29E-83 1.28E-79 2.01E-82 1.85E-81 200 1061 "KLHL32,DPY19L2P4,ZNF608,KLHL13,TBC1D14,NME5,OSBPL6,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,TNRC6C,NCOA1,NUMB,ALDH7A1,ADGRB3,LINC00847,SEC11C,DST,SYNJ1,SCAPER,CA8,CA12,HIP1R,CERS5,CLGN,COPB2,RCBTB2,NDST3,NRXN3,PLAA,CNN3,CPS1,CLOCK,HAPLN1,ANKRD44,SEC24C,SOCS5,PDE4DIP,DZIP3,RIMS2,BOC,KATNAL2,RIPOR2,ARHGAP24,DCAF8,MYEF2,PLPPR4,DMD,CPEB2,DMTF1,ACOT8,DRP2,PDCD6IP,DTNA,EDIL3,EDNRA,RASGRP1,SEMA3D,PHF20L1,AASS,KCTD3,PLEKHA1,RGS17,DCTN4,GPHN,NCALD,ETV1,SIRPB1,GMPR2,ABCA8,SH3YL1,TAOK3,FKTN,FDFT1,KAT8,SLC9B2,OLFM1,FGF14,MEX3B,NBEA,UFM1,ATP6V1H,ATP2C1,ZNF605,STAU2,ZMAT1,MEGF10,IQGAP2,C15orf41,KIAA1841,AHDC1,PCDH17,PPARGC1A,MALT1,CRCP,TOX3,TNRC6A,DCLK2,PRUNE2,PCLO,AP4S1,GUCY1B1,HAS2,MIER3,ELOVL5,ZDHHC15,NEGR1,SMAP1,IRF8,IFI16,ZIC5,RBPJ,ITGAM,STXBP5,LIMS1,HECTD2,NCOA7,MATN2,MATN3,LRP1B,POC1B,COL28A1,BLOC1S2,MYO9A,NCAM2,NF1,GPR137C,CNTN3,PAX6,PCDH9,PDPK1,GNG2,OLA1,PLCL1,PCDH18,TRHDE,EPB41L4B,PPP2R2C,GRAMD1C,DIRAS2,BDNF-AS,PTN,TMEM260,SUSD4,ERI2,BAALC,ATP8B4,RYR3,TRAPPC13,SCN7A,FNIP1,TNFRSF19,SEC14L1,TRA2B,FNDC3A,FHOD3,NLGN1,BTBD3,SEPHS1,SLC14A1,ZFP1,RCOR3,HECW1,MYCBP2,KDM4C,MCF2L2,RBM26,NKAIN2,NXT2,RGL1,KLHL7,NUDT10,EXOC7,SATB2,ZEB1,DOCK9,SIRT1,ITGB3BP,AP4E1,SLC44A1,NR2E1,ERCC6L2,FAM124A,BEX4,CSMD1,AMACR,STXBP4,TSC1,OSBP2,ZNF708,TRIM9,CELF4,ZSCAN26,ADAMTS9,CIAPIN1,NAV3,RNF170,FRMD6,SOCS4" MicroRNA hsa-miR-630:mirSVR_highEffct hsa-miR-630:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-83 1.38E-79 2.17E-82 2.00E-81 214 1217 "ADRB2,SPOP,ABCD2,LRCH2,LCORL,MAP4K3,APBA2,UPRT,TMEFF1,CADPS,ATP1A1,DPY19L3,DOCK11,SCAPER,WASF1,KALRN,SLC25A14,ISPD,ZNF501,MTMR7,CD86,CDH2,LRRFIP1,CFL2,NDST3,CLTC,TMEM184B,COL4A5,ANKRD44,GDA,CS,RGS6,DZIP3,PPP6R2,USP6NL,KATNAL2,TCAF1,ARHGAP24,ZFYVE16,LIN54,TMEM170A,PABPC5,ARMCX2,KLHL3,RHOBTB1,SV2B,SGSM2,CDON,RASGRP1,FRY,FSD1L,PHF20L1,KCTD3,PLEKHA1,DCTN4,LRRC17,F8,CLVS1,ZNF585B,SH3YL1,DLC1,ST3GAL6,SLC9B2,FER,FGF12,FGF14,FLT1,EFCAB2,JKAMP,PDLIM5,AP4B1,HRASLS5,GABRG2,ZNF559,DISC1,CRCP,COPS8,SPIN1,GLI2,MSL3,ZNF782,LNX1,PCLO,GRIA2,PSIP1,GUCY1B1,MAP4K5,RASSF8,FRMD3,MIER3,HMGCR,HNMT,ZDHHC15,CFAP126,LRRC75A,LRRCC1,KCND2,KIF2A,PAXBP1,HECTD2,NCOA7,LSAMP,MAP4,MATN2,MEIS2,KCTD6,POC1B,ADAM22,MSR1,NF1,CNOT4,NTRK2,OPA1,LOC100128398,PCDH9,GPR85,GNG2,PIK3C2A,FAM218A,GPSM2,PURG,LRP12,MINDY2,CEP41,SLC26A11,GRAMD1C,HYDIN,KLK6,ANKHD1,TMEM260,PTPRH,PTPRN2,MARCH1,PID1,CEP97,ZNF793,NWD1,OXR1,RASGRF1,KHDRBS2,RIC8B,SETD5,RORB,ELP2,CCDC102B,ATP8B4,TCP11L1,LRRK2,ABCA11P,ZNF568,ZNF331,FAM192A,SALL1,ATXN2,FNIP1,SUPT20H,SH3BGR,HKDC1,CHD9,BTBD3,WDR47,SEPHS1,CPEB4,ZFP1,LIMCH1,SNRPN,BDP1,MYCBP2,ZC3H13,LMO3,DIP2A,VPS13A,PLCB1,CAMTA1,EXOC7,FAM208A,ADGRL3,PUM2,USP32P1,GPRIN3,FRYL,ITGB3BP,AP4E1,ZMAT3,HEY1,ACTR6,TLR4,TMPO,TPM1,RGMB,METTL3,ANKRD20A2,CLHC1,SGK3,FLRT2,ZNF781,RICTOR,ZNF711,ZNF708,ZNF17,KCNT2,LYPD6,ZNF154,LAMP5,RNF103,ADAMTS9,PDSS2,FAM13C,DOCK8,PHTF2,FBXO36,CASC15,TRAM2-AS1,RNF170" MicroRNA hsa-miR-488:mirSVR_highEffct hsa-miR-488:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.71E-83 2.07E-79 3.24E-82 2.98E-81 225 1347 "FMNL2,ADORA2A,PWWP2A,ADRB2,HECW2,KLHL13,SMIM17,ABCD2,PCDH10,FGD2,CCDC146,APBA2,CADPS,SLC4A4,DPY19L3,ADAM23,BCL7A,SYNJ1,ST3GAL5,ARHGEF7,FUBP1,THSD7A,PTBP2,CCNH,CCPG1,SRSF11,CHN2,NDST3,NRXN3,FAM19A5,ABI3BP,RCHY1,PREPL,CRHBP,HAPLN1,LRIG1,ARHGEF10,PHACTR3,PHF14,CTH,CCDC144A,CYBB,HDAC9,GPRASP1,TCAF1,ZNF337,PITPNC1,ARMCX2,HEPH,FBXL5,KLHL3,WDR20,SEC16A,DMD,USP3,SLC12A6,MAMLD1,E2F6,EBF1,WDPCP,ANKRD46,KLHL5,FSD1L,PLEKHA1,VPS13B,RAB9B,TLR7,CLVS1,FAM198B,ACSL4,CORO2B,CEP78,GORAB,FGFR3,TMEM164,UBE2E3,SLC37A3,SYT3,SMC2,UFM1,FAM49B,TPK1,KHDRBS3,MSANTD4,SDCBP2,GABRB3,RAPGEF6,DISC1,IGSF5,SRCAP,SULT1C4,ARFIP1,PPARGC1A,GLI2,TOX3,GNAO1,PRRC2B,TDRKH,FUT10,STON1,GRIN2D,ADAMTS6,GUCY1B1,HAS2,TNFAIP8L3,HLF,SHISA6,MSL1,ZNF546,IGF1,ZIC5,TJAP1,SCIN,FAM69A,INPP5B,STXBP5,CYP27C1,KTN1,MAP2,MARK1,MBNL1,TAGLN3,RTL5,CCDC13,NEK1,NF1,SMIM11A,SETD4,ZNF827,PCDH9,PRTG,PDE1C,GNG2,PFKFB3,RETREG1,GPSM2,PLIN1,PCDH18,PRIMPOL,LRP12,EPB41L4B,PPM1B,PKIA,MAPK9,GRAMD1C,DIRAS2,RELN,QRICH1,CNTLN,ANKHD1,BDNF-AS,TMEM260,PTPRE,ZNF844,RBBP8,HKR1,KHDRBS2,ERI2,FIGN,RGS4,CCDC82,ZNF532,EXD2,RORB,RPL15,SGSM1,STK32B,ATAT1,NCBP3,AP1AR,SALL1,TRA2B,FERMT1,SHC4,SLC14A1,BTBD7,CDK5RAP2,INTS9,MBD5,CABCOCO1,MYO16,BDP1,PEG10,TROVE2,NKAIN2,ERBIN,MPRIP,RGL1,NECAB1,JMJD6,SYN2,SYT1,ANKRD28,ANKRD12,CAMTA1,PCDHGA11,SLC19A3,PCDHB4,FRYL,DICER1,SLC44A1,TIAM1,TRIO,AMACR,CLHC1,UBC,PLEKHH2,USP1,NPDC1,RICTOR,ZIC1,ZNF711,AGMO,ZBTB38,ANKS1B,ZNF195,UPF3A,PRDM10,HPS4,SLC17A7,KCNAB1,WNK3,KAT6A,SMIM8,NETO2" MicroRNA hsa-miR-1:mirSVR_highEffct hsa-miR-1:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.98E-83 2.23E-79 3.48E-82 3.20E-81 214 1220 "RALGAPA1,ABHD6,KDM5D,NDRG3,HACE1,ALCAM,ARHGAP20,OGT,CCDC146,MAP4K3,APC,UPRT,TMEM108,ZNF582,BMPR1B,SYNJ1,FUBP1,JAZF1,IL33,CA8,KALRN,SEPT7,L3MBTL4,MAGI1,UBE2L6,CHN2,CLCN3,CLTC,C4orf33,LY86,CNN3,COL4A5,SLC4A8,AHCTF1,BAG4,SLC35F1,CREM,RNF14,C1QL2,CRYM,PDE4DIP,DCAF8,MATR3,KCTD8,DGKB,YTHDC1,JAKMIP2,ELMO1,TIAM2,PLPPR4,DLX1,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,EDNRA,EDNRB,MRO,KMT5B,TMEM35A,EPHB1,RABEPK,MRPL37,CDKL3,ADGRV1,ABCA8,CEP78,CHST15,FER,POLR1B,FGFR1,SEC23B,IP6K2,ANKFY1,NELFCD,NBEA,UFM1,ST6GALNAC3,FYB1,GABRA3,DENND2A,HIGD1B,ZNF559,LRRC37A6P,KIAA1841,ARFIP1,PCDH17,PPARGC1A,FERMT2,WDFY3-AS2,ADGRA3,GPD2,MCHR1,ZNF496,RNF165,PSIP1,RASSF8,MIER3,HMGCR,ZDHHC15,IGF1,FAM69A,INSM1,SLC35G1,METTL21A,KIF2A,STXBP5,KTN1,LAMP2,PAXBP1,MAP2,MEIS1,MYO9A,SLC11A2,ZNF713,GPR137C,PDCD2,ENPP2,GNG2,NALCN,CCSER2,KCTD15,PURG,PMP22,TRHDE,SCHIP1,MINDY2,PRKACB,MAPK3,TMEM260,ZIK1,PTPRG,SUSD4,MSANTD2,CRTAC1,SLC25A36,NUDT11,EXD2,C12orf49,CARF,GSTCD,FBXW7,SPIN3,KCNIP3,ZNF568,AP1AR,SCP2,MRAS,TRA2B,SH3GL3,FNDC3A,ANKRD6,PEX26,SLC6A11,SLC8A1,ANKRD36,SNAP25,SNRPN,USP33,SP2,TEX2,RBM26,SAMSN1,LARP4,SS18,NXT2,STAU1,SYN2,TACR1,ALG1,TRIM2,CLASP1,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,LRRC8A,NPL,SYNPO2,TRIO,AMACR,STXBP4,TTC3,RPL7L1,FAM155A,UBE2H,TBC1D15,LMF1,ZNF24,LYPD6,STOX2,TMEM178A,HPS4,WNK3,PARP11,PHTF2,CASC15,ADAMTSL3,TIGD6,MSRB3,ZDHHC20,NETO2,CPNE4" MicroRNA hsa-miR-29c-3p:TargetScan hsa-miR-29c-3p TargetScan 4.14E-83 2.32E-79 3.60E-82 3.31E-81 185 906 "ASIC1,NCKAP5,CCDC85A,RNF150,OSBPL6,PITPNM2,CDC42BPA,PARG,APC,GAS7,ARRB1,ATP2B2,N4BP2L1,BCL7A,PROM1,JAZF1,LDLRAD4,CACNA1A,CACNA1B,CAMK2G,RUNX1T1,L3MBTL4,DLGAP2,CFL2,FOXN3,CNOT8,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,CPS1,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELN,MTSS1L,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,GPR37,CACFD1,RNF165,BVES,HAS2,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,MEST,SCAMP5,MMP16,MXI1,MYCN,NFIX,OXTR,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK10,CNNM2,PTPRD,EML5,NKAIN1,MARCH1,CEP97,RAP1GDS1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,SCN7A,HSPA4L,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,HECW1,ERC1,PEG10,LARP4,ELOVL4,PRRC2C,ADAMTS17,EXOC7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,FAM124A,CLEC2L,EML6,DPYSL5,ADAMTS9,NAV3,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-29a-3p:TargetScan hsa-miR-29a-3p TargetScan 4.14E-83 2.32E-79 3.60E-82 3.31E-81 185 906 "ASIC1,NCKAP5,CCDC85A,RNF150,OSBPL6,PITPNM2,CDC42BPA,PARG,APC,GAS7,ARRB1,ATP2B2,N4BP2L1,BCL7A,PROM1,JAZF1,LDLRAD4,CACNA1A,CACNA1B,CAMK2G,RUNX1T1,L3MBTL4,DLGAP2,CFL2,FOXN3,CNOT8,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,CPS1,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELN,MTSS1L,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,GPR37,CACFD1,RNF165,BVES,HAS2,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,MEST,SCAMP5,MMP16,MXI1,MYCN,NFIX,OXTR,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK10,CNNM2,PTPRD,EML5,NKAIN1,MARCH1,CEP97,RAP1GDS1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,SCN7A,HSPA4L,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,HECW1,ERC1,PEG10,LARP4,ELOVL4,PRRC2C,ADAMTS17,EXOC7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,FAM124A,CLEC2L,EML6,DPYSL5,ADAMTS9,NAV3,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-29b-3p:TargetScan hsa-miR-29b-3p TargetScan 4.14E-83 2.32E-79 3.60E-82 3.31E-81 185 906 "ASIC1,NCKAP5,CCDC85A,RNF150,OSBPL6,PITPNM2,CDC42BPA,PARG,APC,GAS7,ARRB1,ATP2B2,N4BP2L1,BCL7A,PROM1,JAZF1,LDLRAD4,CACNA1A,CACNA1B,CAMK2G,RUNX1T1,L3MBTL4,DLGAP2,CFL2,FOXN3,CNOT8,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,CPS1,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELN,MTSS1L,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,GPR37,CACFD1,RNF165,BVES,HAS2,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,MEST,SCAMP5,MMP16,MXI1,MYCN,NFIX,OXTR,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK10,CNNM2,PTPRD,EML5,NKAIN1,MARCH1,CEP97,RAP1GDS1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,SCN7A,HSPA4L,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,HECW1,ERC1,PEG10,LARP4,ELOVL4,PRRC2C,ADAMTS17,EXOC7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,FAM124A,CLEC2L,EML6,DPYSL5,ADAMTS9,NAV3,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-144*:mirSVR_lowEffct hsa-miR-144*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.14E-83 2.88E-79 4.46E-82 4.11E-81 236 1481 "RALGAPA1,ACTN1,GALNT13,PTCHD1,HECW2,OSBPL1A,OSBPL8,TAOK1,SMIM17,SUGT1P4-STRA6LP-CCDC180,UPRT,PPP4R4,ASPA,NUMB,DPY19L3,DOCK11,SEC11C,CFLAR,DST,MTMR2,JAZF1,WASF1,CACNA1B,THSD7A,RUNX1T1,USP6,DCLK1,COPB2,B4GALT6,RAB28,NRXN3,QKI,FHL5,LETMD1,COL9A3,MAGED1,RCHY1,TBPL1,BAG4,CNRIP1,FAM171B,ANKRD44,IPCEF1,PPP1R16B,ZSCAN23,KIAA0586,DGKG,DAPK1,DNAL1,ZNF804A,TIAM2,KLHL3,PLPPR4,SACS,WDR20,FAM107B,DMD,CD99L2,CPEB2,CASP8AP2,SEMA3D,PHF20L1,RASA4,VPS13B,RABEPK,STX2,DENND4A,DNAJC27,SIRPB1,KATNAL1,NSRP1,SCML2,DLC1,FKTN,SEC24B,SLC9B2,POLR1B,POLK,UBE2E3,MEX3B,SYNCRIP,EFCAB2,TRMO,NBEA,UFM1,FAM49B,NSG1,ZMAT1,TRAF3IP2,ZNF559,DISC1,GATM,IGSF5,NFU1,ADAM28,PPARGC1A,GLI2,RAB30,TOX3,ZNF638,HTATSF1,ADGRA3,STON1,PCLO,STMN2,BTN2A1,RNF165,HAS2,HLF,HNF4G,DHX35,HSF2,IDH3A,IL6R,INSM1,IPO5,STXBP5,PAXBP1,LMO2,MBNL1,MEIS1,KITLG,MID1,MN1,ZC3H12B,NEFM,NEK1,NFE2L2,ALDH1L2,NPR2,NTRK2,OPA1,GLIPR1L2,ETFRF1,ENPP2,PDPK1,PFKFB4,NLGN3,PIK3R1,FAM216A,PLCB2,MAPKAP1,PPM1B,RANBP3L,PRKAB2,CNTLN,ZIK1,PTPRG,PPP2R3C,ZNF793,IQSEC3,FAT4,FAM184A,ENOX1,RBBP6,KHDRBS2,REV3L,NUDT11,DCUN1D2,ROBO1,PCMTD2,MRAP2,NEK11,ARMH4,SPIN3,MCMBP,GLDN,ADAL,MAP6D1,CCDC112,ATXN7,LRFN5,PRCD,SH3GL3,KIF16B,CPEB3,ST6GAL1,CNKSR2,PREX2,SEPHS1,TRIM67,SLC12A2,SLC14A1,SLC22A4,ZFP1,ANKRD36,SNRPN,FAM126B,USP33,FAM219A,PDZD2,BDP1,HECW1,MYCBP2,SPTB,ZNF621,ATP10B,NXT2,STAU1,CEP68,KANK1,VPS13A,COBL,ANKRD12,TBCEL,TCEA1,DMXL2,RPGRIP1L,SYNE1,PCDHB4,SIK3,FAM200B,SIRT1,DICER1-AS1,BEX4,TPM1,RGMB,PDSS1,TSN,SSBP2,UBE2H,WRN,TRIM9,ZNF154,EVI5,HRASLS,FAM13C,PHTF2,FBXO36,JMJD1C,RNF170,MSRB3,FRMD6,NETO2,NETO1,RNF146" MicroRNA hsa-miR-10b:mirSVR_lowEffct hsa-miR-10b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.34E-83 2.99E-79 4.62E-82 4.25E-81 234 1457 "FMNL2,TMEM132B,USP31,ZNF608,MTUS1,PCDH19,KCTD16,TAOK1,CEP126,AMPD2,FGD2,LCORL,CDK10,SFMBT2,SPTBN4,PLA2G4C,CDK13,DYNLL1,CHID1,SLC4A4,ALDH7A1,DPY19L3,BMPR1B,NAE1,LURAP1,CAMK2B,CAMK2G,SPAG9,ZNF501,LRRFIP1,ZNF445,NDST3,FBXO7,MAP4K4,CNGA3,ARMC8,SUMF2,LETMD1,TOGARAM2,HINFP,NCOR1,GDA,ABCG1,CS,LRIG1,CSNK1G3,VAC14-AS1,PDE4DIP,UBXN2A,HDAC4,DAPK1,ARMCX4,RUSC2,POM121,WDR20,GRIN3A,NYAP1,ECM2,DNAJB6,SNX29,FAM13A,MBNL2,IRAK4,COPS4,MRNIP,C3orf18,DCTN4,COQ7,LRRC17,RABEPK,DENND4A,ZNF549,VPS26C,DLC1,PPP1R1B,GORAB,TMEM164,PRKAG2,SEMA4D,FLT1,ANKFY1,JKAMP,ERGIC3,CELF1,CGREF1,CHL1,GALNT15,GABRG1,RAPGEF6,ZNF559,ALDH1L1,WASHC2A,MMADHC,LYVE1,CRCP,SPIN1,MSL3,KCNMB4,TMEM121B,GRIK4,GRM8,LINC01089,BTN2A1,BACH2,GABARAPL2,HNF4G,ZNF491,NEGR1,FAM95B1,IDH3B,CDH20,GPR62,KCNN2,STXBP5,HECTD2,LSS,CLEC18A,ZFYVE27,MAP2,MAP4,MBP,BLOC1S2,MSR1,MYO6,MYO7A,NTRK2,NUCB2,CLDN11,PDE4A,NLE1,SMIM7,SEPT4,GRAMD1C,PSD,BDNF-AS,PTH1R,TMEM260,PTPRO,ZSCAN2,TTC13,CCDC40,ZNF493,ZDHHC14,DPF2,GTDC1,UBR7,KCTD17,MRPS18A,CCDC82,ZNF532,CARF,KIRREL1,RPL15,ARMH4,MCMBP,ZNF568,ZNF331,ATXN7,TNFRSF19,SUPT20H,COPZ1,SGK1,ASAP3,FUZ,FBXO11,FNDC3A,KANSL3,SEPHS1,RADIL,SLC12A2,SLC14A1,BTBD7,CPEB4,MAPKBP1,MBD5,SNRPN,TMCC1,RBM34,SOX3,BDP1,KDM4C,ERC1,UNC5B,TSPYL2,SPART,LHPP,ERBIN,SEPT8,RGL1,KANK1,SEPT3,VPS13A,SYN2,ANKRD28,PJA1,FAM208A,TBCEL,IQCE,NEU4,DMXL2,SATB2,TNS2,DICER1-AS1,AP4E1,MTMR14,TLR4,TMPO,CSMD1,KAT6B,C9orf85,STXBP4,PPIL6,TSC1,OSBP2,FLRT2,ZNF709,VIPR2,WIPF1,CLDND1,CELF4,EML6,SPIRE1,ZFAND5,EMSY,LINC02210,TUBA1A,HPS4,FIP1L1,TRIM16L,PLSCR4,SMIM8,TMEM63C,CPNE4,SENP7" MicroRNA hsa-miR-455-5p:mirSVR_lowEffct hsa-miR-455-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.29E-83 3.52E-79 5.44E-82 5.01E-81 231 1422 "RALGAPA1,ABCF1,FMNL2,PSMG3-AS1,GALNT13,RNF157,UNC5A,KIAA1211,ESYT2,NME5,WDR35,TXNDC16,CC2D2A,SEMA6A,MARCH4,PITPNM2,PHF12,LGR5,SEMA4G,IGDCC4,LINC00173,STK33,MARK4,ADAM15,LINC00847,BBS2,MPDZ,KSR1,BMP7,SYNJ1,SYNJ2,ARHGEF7,JAZF1,RAB29,KALRN,PTBP2,CAMK2A,SLC25A14,NFS1,CLDN10,CERS5,MTMR7,L3MBTL4,LOC730101,CCPG1,IGLON5,IQCK,ARMC8,AKAP6,ABI3BP,ZNF521,AKAP12,HINFP,GDA,RGS6,SUSD5,VCAN,PDE4DIP,CST3,SLITRK5,CTH,RIMS2,KIAA0408,BOC,HDAC9,DGKB,SCRN1,ARMCX4,SPATA2,YTHDC1,MFAP3L,TMEM130,SPOCK3,HS3ST2,ACOT8,EDN1,EDNRB,HIPK3,FSD1L,EGFR,STARD3NL,EPHB1,GPHN,SPEG,REEP2,F8,TMEM132C,FKTN,SPSB4,FGFR1,FHL1,POLK,SUCO,SCARA3,FLNC,PSD2,TMEM107,APOPT1,TVP23A,INPP5K,LRRC37A6P,MSTN,ADAM28,GGT7,LYVE1,CRCP,TOX3,MAP7D2,BTN2A1,RNFT2,GUCY1B1,TOX2,ATXN2L,VSIG4,IRF8,LRRC25,INPP5B,ITPKB,KCND2,KCNN3,GATD1,CYP27C1,NCOA7,GPR155,MAT2A,MBNL1,LRP1B,MEST,MN1,DBNL,N6AMT1,LYRM9,MYO6,NEXMIF,ZNF862,NTRK3,LOC100128398,PALM,PDE4D,GNG2,SERPINI1,KCTD15,LRP12,PPARA,PPP2R5E,KANSL1,MAPK10,NDUFS7,STK32A,PTPRE,PID1,USP47,SH3TC2,SUSD4,GAL3ST4,ZMAT4,TRIM68,PBRM1,CARF,ROBO2,BAALC,STK32B,NCBP3,GALNT10,SH3GL3,FERMT1,FUZ,R3HDM2,NLGN1,DZIP1,ST8SIA1,NUBPL,ABLIM3,SLA,WDR47,SLC6A8,KDM4D,SEPHS1,SLC8A1,ARHGEF40,SLC22A4,CPEB4,COA1,RCOR3,KIF13A,SOX11,HECW1,SPTAN1,NFASC,LHPP,TROVE2,ZC4H2,NKAIN2,NEK4,RGL1,SYN2,COBL,TACR1,EXOC7,ADGRL3,SIN3B,TPCN2,TRIM2,RPGRIP1L,SYNE1,PCDHB9,USP32P1,SIK3,TEK,ZFPM2,MTMR14,PARD3,TPM1,C9orf85,ZNF346,TRPS1,RPL7L1,UGT8,ZBTB14,ZIC1,ZNF711,KCNT2,MKRN3,EMSY,FAM47E,PDSS2,FBXO36,ADAMTSL3,JMJD1C,RNF170,SOCS4" MicroRNA hsa-miR-219-5p:mirSVR_lowEffct hsa-miR-219-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.22E-83 4.04E-79 6.24E-82 5.74E-81 212 1201 "RALGAPA1,CLK4,KDM5D,FMNL2,GALNT13,ZNF608,C1QTNF1,SPARCL1,FAM135A,AMPD3,PHF12,UPRT,LINC00173,CDK13,NUMB,BID,FUBP1,SGCE,GPC2,CALB2,PTBP2,CAMK2G,SEPT7,LRRFIP1,DLGAP1,CFL2,CHGB,CHN2,CNN3,ARHGEF6,ARMC8,LETMD1,ABI3BP,RTTN,RBM39,ANKRD44,GDA,SNCAIP,LRIG1,SIPA1L1,DZIP3,KIAA0040,UBXN2A,PLCXD3,RIMS2,DOCK4,GAPVD1,PABPC5,DNAL1,FBXL5,WDR20,DOCK2,ACOT8,PDCD6IP,DNAJB6,EDIL3,MRO,EIF5,DENND4A,F8,ARMCX1,GORAB,FER,OLFM1,POLR1B,FGF12,FHL1,POLK,FOXF2,SYNCRIP,PSD2,AFF2,NOP56,COQ5,ERGIC3,KHDRBS3,STAU2,AP4B1,MPP6,GALNT15,GATM,SRCAP,SULT1C4,MSTN,ADAM28,PCDH17,TCERG1,RAB30,FUT10,LILRA2,CNTRL,GRB10,GRM8,RNF165,ADAMTS6,ATOH8,ZHX1,ELOVL5,C2orf72,LRRCC1,IL6ST,NME9,KCND2,STXBP5,SYTL4,MAN2A2,LYPLAL1,MAT2A,MBNL1,MEF2C,MEIS1,ADAM22,MT1M,ZC3H12B,NEFM,NOVA1,NUCB2,TBC1D25,CHAMP1,PCSK5,PDE4D,PFKFB3,PIK3C2A,TMIE,STRN3,LRP12,MINDY2,PPP2R2C,PPP2R5E,EPDR1,FITM2,RELN,CNNM2,QRICH1,PIGG,PTN,PTPRN2,TUG1,ZNF844,PPP2R3C,PID1,ZNF793,RGS12,SLC25A36,RNASEL,ROBO1,CCDC102B,FBXW7,RXRA,CCDC112,DGLUCY,SAFB,CSRNP3,HES6,GALNT10,SHC4,FNDC3A,RADIL,CCDC88A,ZNF667,IFT122,PDZD2,DOK5,UHRF1BP1L,ARHGAP26,RBM26,NFASC,RGL1,STXBP1,KLHL7,ZC3H4,PRRC2C,ARHGEF9,VPS13A,TACC1,MCF2L,DNMBP,TBL1X,CUX2,ZEB1,RPGRIP1L,SYNE1,OBSL1,PUM2,FRYL,AP4E1,TK2,TLR4,PRRT1,TP53BP2,NR2C2,UBE2H,FLRT2,TBC1D15,VSNL1,TCEAL7,CELF4,POLR3H,EML6,ANKS1B,PCBP1-AS1,SMARCAD1,MEIS3,INTS3,PRDM8,RNF103,UBE3B,HNRNPA3,KLHDC1,FRMD6,NETO1,CPNE4" MicroRNA hsa-miR-506-3p:TargetScan hsa-miR-506-3p TargetScan 7.55E-83 4.23E-79 6.50E-82 5.99E-81 190 961 "ABR,ACADM,ASIC1,GALNT13,PLEKHH1,ESYT2,KCTD16,OSBPL6,ALCAM,ABCD2,AMPD3,LRFN1,CDC42BPA,PHF12,APBB2,CPNE5,IGDCC4,CASK,ARHGDIA,CADPS,CDK13,ASPA,DPY19L3,ADAM23,RGS9,BMPR1B,ARHGEF7,MTMR3,JAZF1,MYRF,CACNA2D1,CACNB4,PTBP2,DLGAP2,CACNA2D2,CFL2,B4GALT6,LHX2,QKI,CNGA3,CNN3,CNTN1,AKAP6,MYRIP,CPS1,CLOCK,NCOR2,LRIG1,OSBPL3,IPCEF1,PITPNM3,ERC2,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,LONRF1,KCTD8,IST1,AIF1L,GIT2,GUCD1,MTX3,FAM107B,DMD,NR1D2,CDON,DRP2,DTNA,GOLT1B,E2F6,EBF1,EDNRB,PHC2,HIPK3,FEM1B,FSD1L,CELSR3,DCTN4,RAB9B,ETV1,EXTL2,EYA1,MED12L,PRKAG2,PCYOX1,ANKFY1,C2orf88,MPP6,ARFIP1,KIAA1958,FUT10,GPR37,GRIA2,FAM19A2,RNF165,RASSF8,BACH2,HLF,ELOVL5,NEGR1,AGFG1,KCNJ5,KCNK3,KIF2A,KIF5A,PAXBP1,MARK1,MATN2,CHIC1,MID1,PPM1L,MITF,AFF1,MMP16,MN1,MYO5A,NEFM,NFIX,CLDN11,P2RX7,CNTN3,PCDH8,CDK18,PDE4A,PDE4D,GPR85,PIK3C2A,FSD1,PPARA,PPP2R5E,CEP41,MAPK4,MAPK7,MAPK10,QRICH1,PTPRD,EML5,QDPR,PID1,RAD17,ENOX1,DUSP15,MORC4,RFX3,ALG9,CYB561D1,RXRA,RYR3,SCN7A,CASC3,COPZ1,DZIP1,EPN2,CCDC88A,ATF7IP,LIMCH1,FAM219A,PDZD2,GLT8D1,NFASC,CAMTA2,NKAIN2,NXT2,CEP68,PHLDB1,KANK1,RHBDL3,ATMIN,CRTC1,GPRIN3,DICER1,NACC2,CBX5,RIMBP2,OSBP2,KLC2,RICTOR,LYPD6,REEP1,EML6,DPYSL5,CADM2,NT5M,NAV3,MARCH8,PHTF2,FAM219B" MicroRNA hsa-miR-124-3p.2:TargetScan hsa-miR-124-3p.2 TargetScan 7.55E-83 4.23E-79 6.50E-82 5.99E-81 190 961 "ABR,ACADM,ASIC1,GALNT13,PLEKHH1,ESYT2,KCTD16,OSBPL6,ALCAM,ABCD2,AMPD3,LRFN1,CDC42BPA,PHF12,APBB2,CPNE5,IGDCC4,CASK,ARHGDIA,CADPS,CDK13,ASPA,DPY19L3,ADAM23,RGS9,BMPR1B,ARHGEF7,MTMR3,JAZF1,MYRF,CACNA2D1,CACNB4,PTBP2,DLGAP2,CACNA2D2,CFL2,B4GALT6,LHX2,QKI,CNGA3,CNN3,CNTN1,AKAP6,MYRIP,CPS1,CLOCK,NCOR2,LRIG1,OSBPL3,IPCEF1,PITPNM3,ERC2,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,LONRF1,KCTD8,IST1,AIF1L,GIT2,GUCD1,MTX3,FAM107B,DMD,NR1D2,CDON,DRP2,DTNA,GOLT1B,E2F6,EBF1,EDNRB,PHC2,HIPK3,FEM1B,FSD1L,CELSR3,DCTN4,RAB9B,ETV1,EXTL2,EYA1,MED12L,PRKAG2,PCYOX1,ANKFY1,C2orf88,MPP6,ARFIP1,KIAA1958,FUT10,GPR37,GRIA2,FAM19A2,RNF165,RASSF8,BACH2,HLF,ELOVL5,NEGR1,AGFG1,KCNJ5,KCNK3,KIF2A,KIF5A,PAXBP1,MARK1,MATN2,CHIC1,MID1,PPM1L,MITF,AFF1,MMP16,MN1,MYO5A,NEFM,NFIX,CLDN11,P2RX7,CNTN3,PCDH8,CDK18,PDE4A,PDE4D,GPR85,PIK3C2A,FSD1,PPARA,PPP2R5E,CEP41,MAPK4,MAPK7,MAPK10,QRICH1,PTPRD,EML5,QDPR,PID1,RAD17,ENOX1,DUSP15,MORC4,RFX3,ALG9,CYB561D1,RXRA,RYR3,SCN7A,CASC3,COPZ1,DZIP1,EPN2,CCDC88A,ATF7IP,LIMCH1,FAM219A,PDZD2,GLT8D1,NFASC,CAMTA2,NKAIN2,NXT2,CEP68,PHLDB1,KANK1,RHBDL3,ATMIN,CRTC1,GPRIN3,DICER1,NACC2,CBX5,RIMBP2,OSBP2,KLC2,RICTOR,LYPD6,REEP1,EML6,DPYSL5,CADM2,NT5M,NAV3,MARCH8,PHTF2,FAM219B" MicroRNA hsa-miR-331-5p:mirSVR_lowEffct hsa-miR-331-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.20E-83 4.59E-79 7.04E-82 6.49E-81 215 1236 "ASIC1,CLK4,PTCHD1,DPY19L2P4,ZNF608,TAOK1,FAM135A,DPP10,CCDC146,APAF1,EPB41L5,BCAS1,ATP1B3,N4BP2L1,BCHE,BMPR1B,JAZF1,CAST,SPAG9,CLDN10,SEPT7,LRRFIP1,L3MBTL4,DLGAP2,RCBTB2,PLEKHB1,MS4A7,RAB28,C4orf33,QKI,TMEM184B,SULT4A1,ARMC8,FAM149A,AKAP6,COL9A1,SLC4A8,ZFP28,FAM171B,CLOCK,AKAP12,HAPLN1,ANKRD44,ABCG1,PDE4DIP,PNPLA8,CYBB,KATNAL2,ZFYVE16,AIF1L,ARMCX4,PITPNC1,DDX46,SNAP91,SV2B,EXOG,RAB39B,E2F6,EBF1,HIPK3,YAF2,EGFR,MBNL2,GOLGA7,STARD3NL,IGSF6,GMPR2,NRN1,ARMCX1,ABCA8,SH3YL1,ACSL4,DLC1,FKTN,FGF11,SCARA3,IP6K2,SYNCRIP,JKAMP,APOPT1,ZNF605,FYB1,HRASLS5,GALNT15,GCNT2,CYP46A1,GHR,RNPS1,HTATSF1,GNG4,GPD2,PLCD4,CLASRP,GUCY1A1,UBE2QL1,ZDHHC15,CELF5,SMAP1,IDH3A,C2orf72,RBPJ,KIAA1755,IL6ST,INPP5B,SLC35G1,A1BG-AS1,IPO5,LAMP2,HECTD2,NCOA7,SMAD1,SMAD9,MBNL1,LRP1B,MEF2C,KCTD6,KITLG,MN1,NRCAM,CHAMP1,OPA1,P2RY1,PAX6,PCDH9,ZDHHC8,SERPINI1,SEMA5B,PIK3C2A,FAM218A,RETREG1,PLCL1,PURG,PDZRN4,PMP22,MAGEL2,ING3,DRAM2,PPM1B,PPP2R5E,PRPSAP2,LAMA1,GDPD2,ANKHD1,PTPRG,PTPRO,PPP2R3C,SH3TC2,IQSEC3,RASGRF1,KHDRBS2,ZDHHC14,REV3L,PBRM1,ZFHX4,RORB,RPE,RPL15,MCMBP,CLIP1,RYR3,SEMA6D,ATXN7,CASC3,SCAF8,KIF16B,FNDC3A,R3HDM2,ST6GAL1,CNKSR2,SEC31A,SIRT2,SLC14A1,CPEB4,MAST1,LIMCH1,MBD5,FAM219A,SPATA7,KDM4C,SPTB,TSPYL2,TROVE2,LARP4,COBL,CAMTA1,SMG6,ZEB1,TRIM2,SYNE1,AKTIP,SLC44A1,ACTR6,BHLHB9,NPL,SMUG1,STXBP4,SLC35A4,UBE3A,UGT8,VLDLR,RICTOR,GUSBP1,ZIC1,ZNF23,TRIM9,EMSY,MDH1B,FAM47E,WNK3,PDSS2,RGS7BP,FAM13C,RNF170,FXR1,FAM198A" MicroRNA hsa-miR-135a:mirSVR_highEffct hsa-miR-135a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.11E-82 6.19E-79 9.50E-82 8.74E-81 232 1438 "ADCY6,GALNT13,PLEKHH1,PTCHD1,INTS2,MTUS1,ALCAM,LRCH2,PHF12,PKP4,APC,TMEFF1,ZFYVE28,ARNTL,RGS20,PDE8B,NUMB,N4BP2L1,ADAM23,BACH1,DST,ARHGEF7,CA12,CACNB4,CALM1,KALRN,PTBP2,CAMK2G,CAPN3,RUNX1T1,ZNF501,LDB2,ARHGEF2,KCNAB3,L3MBTL4,LOC730101,UBE2L6,SOCS6,QKI,ARHGEF6,CNTN1,FAM149A,ZFP28,PREPL,ENTPD4,HAPLN1,RGS6,ARHGEF10,CSNK1G3,VCAN,SLITRK5,APPL1,UBXN2A,BOC,ARHGAP32,LONRF1,KIAA0586,PITPNC1,JAKMIP2,MYEF2,GSDME,DDX46,FAM107B,CHRDL1,EXOG,RAB39B,PDCD6IP,E2F5,EBF1,EDIL3,EDNRA,ANKRD46,HIPK3,YAF2,PHF20L1,GOLGA7,PLEKHA1,CERCAM,MRNIP,COQ7,SRRM1,EYA1,MRVI1,F8,CLVS1,FAM198B,SCML2,FDFT1,FGFR1,POLK,HPCAL4,SYNCRIP,PSD2,NBEA,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,STAU2,TVP23A,OGA,ERAP1,CPLX2,GCNT2,GHR,PPARGC1A,BRD8,RAB30,FERMT2,PSIP1,ELOVL5,AGBL5,ZDHHC15,IRF8,IL6ST,JAK2,KCND1,STMN1,MBD1,MEIS1,ZNF92,MYO6,P2RY13,NEFM,NPTX1,NTRK2,OXTR,PCDH9,PDCD2,PCDH18,PURG,STRN3,SCHIP1,SDK2,DRAM2,MINDY2,PPM1B,MAPK9,GDPD1,MASP1,RELN,APTX,ELOVL2,PTK2,ZSCAN32,RAP1GDS1,ZCWPW1,ENOX1,RDX,ERI2,SLC25A36,PBRM1,ROBO1,CCDC25,RORB,PCMTD2,ATAT1,ATXN7,SCN8A,PPM1E,ASAP3,NUBPL,SLA,ZNF430,SLC8A1,CCDC88A,ZFP1,ZNF667,COA1,MBD5,SNRPN,DOP1A,PDZD2,BDP1,HECW1,ZNF302,NXT2,SEPT8,RGL1,DIP2A,KANK1,ARC,MTCL1,KLHL4,ATMIN,SATB2,CUX2,TCF12,SYNE1,PMS2CL,SIRT1,C18orf54,ITGB3BP,SLC44A1,TMEM9,BHLHB9,ERCC6L2,FAM124A,KAT6B,NPL,SYNPO2,CLHC1,RPL7L1,UGT8,VLDLR,TBC1D15,WIPF1,XRCC4,ZNF708,TRIM9,NDRG4,ZNF138,TMEM237,FTSJ1,ZFAND5,INTS3,EMSY,DNALI1,EVI5,RNF103,NAV3,PLSCR4,DOCK8,ST7,RTN4,KLHDC1,FRMD6,IFT88,NETO2,GAN,FAM198A" MicroRNA hsa-miR-4300:mirSVR_lowEffct hsa-miR-4300:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-82 6.26E-79 9.59E-82 8.83E-81 217 1261 "VWA5B2,ASIC1,ACHE,SYS1,ACTN1,KLHL32,ADCY6,PTCHD1,AP2A2,C1QTNF1,PCDH10,ZFAT,OGT,KCNAB2,SFMBT2,SEMA4G,PRX,PCDHGB4,ADAM15,ADGRB1,LINC00847,BBS2,KSR1,CASTOR3,AP1M1,CFAP410,CA8,LURAP1,CALB2,HAP1,ISPD,CD86,CBFA2T2,DGKI,SRSF11,PLEKHB1,B4GALT6,TAOK2,PPT2,FBXO7,MAP4K4,ARMC8,CABP1,ANKRD44,CS,SNCAIP,CSF1R,PLXNA4,KATNAL2,HDAC4,DGKB,DGKG,ZNF804A,DOCK2,SLC12A6,COPS4,C3orf18,VPS13B,EPB41,EPB41L2,COQ7,EPHB1,RASL12,SIRPB1,CD320,PTK2B,KAT8,SPSB4,POLK,SUCO,ANKFY1,AK8,PDLIM5,USP21,CELF1,CGREF1,NSG1,STAU2,AP4B1,ABLIM2,GHDC,CPLX2,GCK,ALDH1L1,SRCAP,TTBK1,RAB30,KDM2B,POLL,LUZP2,GPD1,GPD2,FUT10,GPR12,ATP2B1-AS1,GRB10,GRIA2,BTN2A1,GSTM5,KAT7,GSTT2,FAM107A,ATOH8,ZHX1,ATXN2L,ARHGAP36,ZDHHC15,SHISA6,LRRC25,KCNJ5,CREG2,TTYH2,MAN2A2,DBNL,SAMD5,MYT1,NBL1,NFE2L2,NNAT,NOVA1,SMIM11A,PCDHGC3,NLGN3,FAM216A,PLCB2,PLIN1,FXYD1,PRIMPOL,ANKRD16,EPB41L4B,C19orf57,NKAIN4,WBP1L,TMEM260,STK32A,SLC25A48,ZNF793,SUSD4,RDX,GAL3ST4,RGS4,YY1AP1,SNX22,KIAA0895L,LRRK2,ATAT1,CSRNP3,PRCD,CASC3,SYBU,ST8SIA1,SLA,SIRT2,SMARCC2,MAPKBP1,SNCA,MBD5,SNRPN,BDP1,TSNAXIP1,SP2,KDM4C,PEG10,CDK19,LMO3,ZSCAN29,APOM,RHBDL3,ARHGEF9,SYN1,FBXW11,NEU4,ZEB1,TPCN2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NAT16,SIK3,RNF216P1,DICER1-AS1,TIAM1,TMEM9,ERCC6L2,FAM124A,PIK3R5,IL34,WBP2,TRPM2,TSC1,SLC35A4,OSBP2,TBC1D15,CLIP2,KLC2,ZNF70,LYPD6,TMEM198,DNALI1,SLC38A1,URM1,FBXO36,RNF170,NETO1,AP3B2,LAS1L,FAM198A" MicroRNA hsa-miR-194:mirSVR_highEffct hsa-miR-194:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.20E-82 6.69E-79 1.02E-81 9.42E-81 189 953 "ACHE,NDRG3,PTCHD1,DPY19L2P4,KLHL13,OSBPL8,TAOK1,ALCAM,FAM135A,PITPNM2,DPP10,LRCH2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,ZFYVE28,ZBTB10,TMEM108,STX16,ALDH7A1,SYNJ1,ARHGEF7,MTMR2,SGCE,KALRN,SLC25A14,PRC1,LDB2,KRIT1,CCNH,LRRFIP1,DLGAP1,CFL2,SRSF11,CHN1,QKI,AKAP6,SLC4A8,ABI3BP,AHCTF1,BAG4,TOGARAM2,SLC35F1,SEC31B,ENTPD4,RBM39,MROH8,CSF1,USP6NL,ARHGAP32,HDAC4,IST1,ELMSAN1,SNAP91,WDR20,SLC12A6,DPP6,DNM1L,GOLT1B,E2F5,E2F6,WDPCP,EDN1,CELSR3,MBNL2,KMT5B,AASS,NRN1,ZNF585B,FDFT1,GORAB,FER,FGF12,POLK,SEC23B,IP6K2,ANKFY1,JKAMP,ATP6V1H,ATP2C1,ZNF605,STAU2,OGA,ZMAT1,GAD1,IQGAP2,INPP5K,NEU3,TUBGCP4,MSTN,BRD8,COPS8,TNRC6A,GRIA2,ATE1,GSTT2,GUCY1B1,ZHX1,MSL1,TJAP1,KCND2,KCNN2,LAMP2,STMN1,LIMS1,HECTD2,MEIS2,MEST,MIA2,MITF,AFDN,IGSF11,LOC100128398,GLIPR1L2,DPY19L2P2,PFKFB2,OLA1,SCHIP1,RETREG2,MINDY2,PPP3CA,GRAMD1C,TMEM260,PTPRD,ZNF615,USP47,FAM184A,KHDRBS2,PBRM1,RNASEL,ZFHX4,SETD5,PNMA8A,GSTCD,FBXW7,SPIN3,ATP8B4,LRRK2,RTN1,TRAPPC13,DGLUCY,SALL1,ATXN7,FNIP1,PPM1E,WDR37,KANSL3,SEPHS1,SLC12A2,BTBD7,ATF7IP,ZFP1,LIMCH1,SNRPN,SOX3,FNBP1,SP4,PEG10,LMO3,CLASP2,SS18,TTBK2,ADHFE1,TMEM150C,MTCL1,PJA1,KLHL4,TCEA1,SIRT1,C18orf54,AP4E1,SLC44A1,RIMBP2,KAT6B,TRPS1,WRN,RICTOR,TRIM9,EMSY,STOX2,GAL3ST3,WNK3,PARP11,DOCK8,RTN4,UBE3B,ACTR3B,MSRB3,IFT88" MicroRNA hsa-miR-635:mirSVR_lowEffct hsa-miR-635:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-82 9.02E-79 1.38E-81 1.27E-80 239 1526 "ABR,GALNT16,ADCY6,BEND6,OLMALINC,KCTD16,NME5,USP35,ABCD2,ZNF687,PDZD4,SEMA7A,FGD2,FAM131A,PPFIA3,SHROOM2,AQP6,PRX,SPTBN4,RNF182,ATP6V0A1,ADGRB2,RGS11,CFLAR,KSR1,ARHGEF7,SCAPER,RAB29,IL33,CALB2,CABP7,CALM1,KALRN,CAMK2G,HIP1R,CLDN10,USP2,MAGI1,RCBTB2,FOXN3,NRXN3,TPP1,NGEF,MAP4K4,PCYT1B,LETMD1,MYRIP,ZNF385A,SEC31B,C2CD2,CREM,RNF14,HINFP,CS,SNCAIP,RGS6,SOCS5,CST3,DCAF4,FAM131B,CCDC144A,ARHGAP32,ZFYVE16,TBC1D5,IP6K1,ELMSAN1,KIAA0753,SV2B,NYAP1,SLC29A4,CDON,DPH1,E2F6,TMTC1,FAM13A,ELN,EMX2,VPS13B,RABEPK,ERBB2,SPEG,FAM198B,CORO2B,FCGR3A,STRADA,FGF1,FGF12,HPCAL4,IP6K2,EVL,SEMA4D,FLT1,NOP56,FLYWCH1,COQ5,EFCAB2,ZBED3,PDLIM5,FYB1,HRASLS5,IP6K3,DISC1,SEPT9,CYP46A1,USP19,GGT7,BRD8,RNPS1,GLI2,TNRC6A,ZNF638,GNAL,GNG4,WDFY3-AS2,ADGRA3,PLCD4,ZBTB45,ATOH8,HAS2,PADI2,HNF4G,NEGR1,AGFG1,DHX35,SHISA6,C2orf72,RBPJ,SLC35G1,KCNJ5,GATD1,KIF5A,SYTL4,ZFYVE27,ADAM11,TM6SF1,MEIS1,MEIS2,MID1,MITF,XRRA1,MSR1,HS6ST3,MYO7A,RTL5,NCF2,PFKFB4,NALCN,PIK3R1,ZNF655,MAPK4,EPDR1,WBP1L,BDNF-AS,TMEM260,PTPRH,ZNF615,FAM66C,NWD1,KHDRBS2,ZDHHC4,RGS3,RGS12,PRIMA1,RIC8B,ROBO2,CCDC25,MRAP2,SNX22,KIAA0895L,SGSM1,ADAL,ZNF331,SEMA6D,SCN2B,SCN8A,SCP2,FNIP1,TNFRSF19,SH3GL3,MYO18A,AMBRA1,FBXO11,ST6GAL1,ANKRD6,ABLIM3,KANSL3,SLC12A4,NAPB,ATF7IP,CDK5RAP2,SNRPN,TMCC1,RBM34,USP33,FAM219A,DOP1A,TSNAXIP1,SP2,KDM4C,PEG10,ZC3H13,ZBTB43,DDN,PBLD,ITPRID2,RGL1,SULF2,SYNE2,NUDT10,SYP,SYT1,TACR1,FAM208A,SYNE1,PHF24,RNF175,SIK3,FAM200B,AP4E1,ZNF106,TK2,RASD2,C9orf85,TRIO,TRO,STXBP4,TSC1,SGK3,RPL7L1,NDRG4,FTSJ1,DHX33,GDPD5,HPS4,NAV3,RTN4,UBE3B,IFT88,SOCS4" MicroRNA hsa-miR-34b:mirSVR_highEffct hsa-miR-34b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-82 9.87E-79 1.50E-81 1.39E-80 213 1218 "ABCF1,KCNH8,CLK4,ABHD6,NCKAP5,NDRG3,PWWP2A,ADRB2,MTUS1,ABCD2,MARCH4,OGT,LRCH2,APBA2,SHROOM2,CASK,DPY19L3,ADGRB3,SEC11C,DST,SCAPER,CALM1,PTBP2,ISPD,SPAG9,CCK,C1orf52,L3MBTL4,MAGI1,CHN2,NDST3,QKI,FHL5,MYRIP,CNRIP1,HAPLN1,HINFP,GDA,TRIM69,ARHGEF10,VCAN,ARHGAP32,LIN54,DGKB,KIAA0319,DMD,DNAH9,ACOT8,DTNA,DTNB,E2F5,EDNRA,EDNRB,FAM13A,PHF20L1,APH1A,MBNL2,TENM1,PLEKHA1,EMX2,RCAN2,DENND4A,IGSF6,EYA1,ZSCAN30,FGF14,FGFR1,PSD2,COQ5,C2orf88,UFM1,FAM49B,ATP6V1H,GABRB3,TRAF3IP2,GALC,MTHFD2,CPLX1,ARFIP1,GDF9,MMADHC,PCDH17,ZNF638,CBX1,RAB40B,GPR12,PCLO,CNTRL,UBE2QL1,ZHX1,FRMD3,MSL1,RBPJ,ZNF678,CREG2,KIF2A,KIF5A,NCOA7,PIK3AP1,MAP2,LYPLAL1,MARK3,MEST,MIA2,AFDN,ADAM22,MSR1,LYRM9,LAYN,MYO9A,MYT1,NINJ2,DNHD1,NUCB2,P2RY1,GPR137C,CNTN3,PDE4D,GPR85,ZNF655,CCSER2,PLCL1,LRP12,PSAT1,SCHIP1,EPB41L4B,PPM1B,TATDN3,KANSL1,PRKACB,RELN,VPS13C,WDR25,ANKHD1,SPDL1,TMEM260,PTPRD,PTPRE,ZSCAN2,SLC25A48,GTDC1,FIGN,RIC8B,PBRM1,SETD5,CARF,ROBO2,ELP2,RPE,NEK11,ARMH4,AP1AR,ATXN2,SCP2,MRAS,SCAF8,KIF21A,CPEB3,CHD9,FNDC3A,NLGN1,ANKRD6,SEPHS1,SLC12A2,ELMO2,BTBD7,ATF7IP,TET1,RCOR3,SNAP25,SNCA,MBD5,SNRPN,FAM126B,MYO16,ZNF423,ZC3H13,CDK19,SPART,LMO3,PBLD,SS18,NXT2,TTBK2,KLHL7,VPS13A,NUDT10,ADGRL3,USP22,PCDHB4,PCDHB3,PUM2,USP32P1,ARHGAP9,GPRIN3,ZNF106,AKTIP,ASXL3,TP53BP2,DCBLD1,TSN,ANKRD20A2,RPL7L1,RICTOR,PCDH20,LAMP5,SMARCAD1,PDSS2,KAT6A,PHTF2,CASC15,TIGD6,SNX14" MicroRNA hsa-miR-139-5p:mirSVR_highEffct hsa-miR-139-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.61E-82 1.46E-78 2.22E-81 2.04E-80 183 895 "RALGAPA1,ACADM,CLK4,NDRG2,KLHL32,AXIN2,PWWP2A,CC2D2A,TAOK1,PCDH10,FAM135A,LRCH2,ANK2,EP400,PKP4,UPRT,DDO,IGDCC4,PCDHGB4,ZBTB10,STX16,ADGRB3,BBS2,SCAPER,CA12,SPAG9,C1orf52,MAGI1,CDO1,CCPG1,RCBTB2,FHL5,ARHGEF6,ARMC8,CREM,GDA,SOCS5,USP6NL,ARMCX4,KIAA0319,SPOCK3,CHRDL1,DMD,ABCC5,DNM1L,EBF1,TSPAN5,YAF2,MBNL2,EIF4G2,PLEKHA1,MRVI1,CLVS1,SCML2,POLK,UBE2E3,FLT1,PSD2,STAMBP,ATP2C1,STAU2,FYB1,ZNF234,ERAP1,GATM,GLI2,TNRC6A,MSL3,ZNF638,CBX1,LPAR4,GPR37,CNTRL,ATP2B1-AS1,RASSF8,ELOVL5,HMGCR,HNF4G,FAM95B1,ZNF181,ZNF678,KCND2,PAXBP1,HECTD2,LSS,PACRG,MAP2,MARK1,LYPLAL1,MAT2A,MBD1,MEIS2,AFDN,MYO9A,NDP,CNOT4,NPTX1,NRCAM,OCRL,GLIPR1L2,PCDHGC3,PDE3A,PDE4A,PDE4D,XRN1,PMP22,LRP12,PSAT1,SCHIP1,DRAM2,PPM1B,MAPK9,VPS13C,PTPRD,EML5,ZNF493,RASGRF1,PBRM1,ZNF532,MRAP2,TCP11L1,FAM161B,ZNF331,LRFN5,RASA3,ARX,FHOD3,R3HDM2,WDR47,ATF7IP,MYH15,KIF13A,TROVE2,ZNF302,SST,ERBIN,PLCB1,FAM208A,SATB2,ZFP90,ZEB1,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,PCDHB7,GPRIN3,FRYL,TEK,TP53BP2,C9orf85,TRPS1,DCBLD1,HIRA,UBE3A,P2RY12,CLDND1,RICTOR,LGI4,ZNF19,TRIM9,ELFN1,NDRG4,ZNF177,FSTL5,ZSCAN26,ANKS1B,SPIRE1,ADAMTS9,FZD3,RTN4,KAT6A,JMJD1C" MicroRNA hsa-miR-138-2*:mirSVR_highEffct hsa-miR-138-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-82 1.47E-78 2.24E-81 2.06E-80 230 1420 "ESYT2,PTCHD1,SMIM17,ABCD2,OGT,LCORL,PHF12,APAF1,APBA2,TNRC6C,TMEFF1,ASPA,NCOA1,JAZF1,RAB29,CA8,CAST,C1orf52,LRBA,ZMYM4,LARGE1,CCPG1,CFL2,SRSF11,NDST3,SLIT2,ABCG2,COL4A5,SLC4A8,TBPL1,IGDCC3,RBM39,SEC24C,CSNK1G3,SUSD5,VCAN,DZIP3,APPL1,GREB1,CCDC144A,TCAF1,RIPOR2,ARHGAP24,ZFYVE16,KIAA0586,KCTD8,DGKB,DAPK1,ALKBH8,PLPPR4,NR1D2,DMTF1,PDCD6IP,DTNA,GOLT1B,E2F6,WDPCP,EDNRB,HIPK3,KLHL5,KMT5B,ING4,EMX2,RCAN2,ZNF549,EYA1,ABCA8,FCGR1A,CEP78,FER,MED12L,SUCO,SYNCRIP,FOXO3,UFM1,ERGIC3,KHDRBS3,ST6GALNAC3,CSPG5,MSANTD4,OGA,FYN,MEGF10,GAD1,RAPGEF6,C15orf41,KIAA1841,LYVE1,SPIN1,RAB30,FERMT2,LPAR4,PCLO,GRIA2,DIDO1,LINGO1,PSIP1,MIER3,GABARAPL2,EID2B,MSL1,ZNF181,SOWAHA,IGF1,LRRCC1,IL6ST,LRRTM1,SLC35G1,KCNB1,KIF5A,STXBP5,LIG4,SMAD1,MARK1,MAT2A,MATN3,KCTD6,MIA2,PPM1L,POC1B,COL28A1,TAGLN3,MYO5A,MYO9A,NDP,NF1,SLC11A2,NRCAM,OGG1,FAM98B,PIK3C2A,XRN1,PRIMPOL,PDZRN4,ING3,RETREG2,SH3KBP1,MAPK9,GRAMD1C,HYDIN,CNTLN,TMEM260,SH3TC2,FAM184A,ZDHHC14,KLHL11,RIC8B,ZFHX4,CARF,ROBO1,ROBO2,ELP2,CCDC102B,NEK11,STK32B,LRRK2,ZNF568,TRAPPC13,CSRNP3,SCP2,FNIP1,FBXO11,FHOD3,WDR37,FAM81A,PPP4R3A,SEPHS1,CCDC88A,BTBD7,CPEB4,GKAP1,LIMCH1,SNAP25,SNCA,MBD5,CMTR2,USP33,PDZD2,TRERF1,SP4,KDM4C,RBM26,LMO3,ATP10B,CLASP2,POGZ,NXT2,NEK4,RGL1,KLHL7,ZC3H4,PLCB1,ANKRD28,MTCL1,CAMTA1,ADGRL3,IQCE,TBL1X,TCF12,GPRIN3,ZFPM2,AP4E1,THRA,HEY1,WBP2,RGMB,ANKRD20A2,TUBB1,RPL7L1,BCL2L13,VGF,CCDC14,RICTOR,PCDH20,MICU3,KCNT2,MKRN3,SMARCAD1,EMSY,EVI5,PRDM10,RNF103,VPS35L,FIP1L1,HNRNPA3,NHSL1,FXR1,FRMD6,NETO1,DPF3" MicroRNA hsa-miR-132:mirSVR_highEffct hsa-miR-132:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.18E-82 1.78E-78 2.70E-81 2.49E-80 195 1022 "ACADM,NCKAP5,AXIN2,PWWP2A,KIAA1211,ESYT2,CC2D2A,SEMA6A,PCDH10,SEMA7A,PHF12,APAF1,DDO,SEMA4G,TMEFF1,PDE8B,RNF182,DPY19L3,FUBP1,CACNA1B,CALB1,PTBP2,SLC25A14,HIP1R,CLDN10,CBFA2T2,DGKI,LRBA,CDC25B,LRRFIP1,LARGE1,CFL2,SRSF11,RAB28,FBXO7,ARMC8,LETMD1,ZNF521,HAPLN1,ABCG1,CSF1,CSNK1G3,DOCK4,ARHGAP32,RIPOR2,KIAA0586,ELMSAN1,ZBTB24,ALKBH8,RHOBTB1,SPOCK3,DMD,USP3,E2F5,EDN3,EDNRA,CELSR3,PHF20L1,KMT5B,ASB3,EPB41,DENND4A,NCALD,EXTL2,CEP78,KAT8,PRKAG2,FOLR2,TRMO,TPK1,ATP6V1H,ZNF605,ST6GALNAC3,RAPGEF6,ERAP1,INPP5K,SULT1C4,AHDC1,NFU1,GHR,MSL3,CBX1,GPD2,GRIA2,SPACA9,ATE1,FAM19A2,PSIP1,HAS2,MIER3,SMAP1,EID2B,MSL1,SOWAHA,TJAP1,ZNF678,NME9,KCNJ16,KTN1,LIMS1,PACRG,PIK3AP1,MBNL1,MEIS1,MEIS2,ADAM22,ZNF862,HNRNPM,NFE2L2,NOVA1,NRCAM,NTRK2,IGSF11,PRTG,SLC10A4,CCSER2,MAPKAP1,ING3,EPB41L4B,PPP2R5E,MAPK3,HYDIN,RELN,SNRK,MTMR10,PTPRD,PEX2,FAM184A,OXR1,RADX,KHDRBS2,GAL3ST4,GTDC1,RFX3,ZFHX4,CCDC82,SETD5,EXD2,TCP11L1,SALL1,CSRNP3,ATXN7,SEC14L1,ARX,SEC31A,FAM81A,EPN2,SEPHS1,ARHGEF40,SLC12A2,MTERF2,RCOR3,FNBP1,MYCBP2,CDK19,ZBTB43,POGZ,SS18,ERBIN,SEPT8,PRRC2C,SYNE2,VPS13A,SYN2,MMS19,DNMBP,ADGRL3,AGTPBP1,DOCK9,PCDHB6,PUM2,SIRT1,AP4E1,SLC44A1,TRIO,NEIL2,TSN,HIRA,SGK3,PLEKHH2,WIPF1,ZBTB14,ZNF708,TRIM9,NDRG4,CELF4,TMEM178A,RGS7BP,FAM13C,RTN4,CASC15,FXR1,FRMD6,IFT88,RNF146" MicroRNA hsa-miR-29b:mirSVR_highEffct hsa-miR-29b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.31E-82 1.85E-78 2.81E-81 2.59E-80 213 1222 "KCNH8,NCKAP5,KDM5D,XKR4,OSBPL1A,OSBPL6,TXNDC16,SMIM17,SPOP,ALK,AMPD3,DPP10,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PARG,APC,UPRT,BCAS1,TMEFF1,CDK13,MARCH3,STX16,ATP2A2,N4BP2L1,RIPK1,ADGRB2,PROM1,DST,NAE1,WASF1,PTBP2,RUNX1T1,C1orf52,DGKI,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,ANKRD44,GDA,CRYM,CS,LRIG1,ARHGEF10,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,RHOBTB1,EXOG,GRIN3A,DYNC1I1,DNM1L,WDPCP,EDNRB,FEM1B,PHF20L1,KMT5B,ELN,TUBD1,SCML2,MED12L,MEX3B,RGPD5,DCTN2,TPK1,ATP2C1,ST6GALNAC3,NSG1,OGA,FYB1,GABRG2,DISC1,SESN1,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,GPR37,PCLO,ADAMTS6,ZHX1,VSIG4,HMGCR,HNF4G,IGF1,SCIN,ZNF678,KIF5A,LAMA2,LIMS1,HECTD2,MAP6,TM6SF1,MEIS1,MEST,MYCN,MYO9A,NEXMIF,NRCAM,ENPP2,GNG2,CCSER2,PURG,ANKRD16,PMP22,SDK2,ING3,EPB41L4B,PRKAB2,RASGEF1B,SLC26A11,GRAMD1C,MASP1,VPS13C,SNRK,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,CCDC82,ROBO1,PCMTD2,FBXW7,ATAT1,SALL1,TRA2B,SGK1,SH3BGR,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,WDR47,SLC12A2,NAPB,ELMO2,BTBD7,TET1,ZKSCAN3,SNCA,MYO16,HECW1,UHRF1BP1L,KDM4C,SPTAN1,NXT2,ZSCAN29,ELOVL4,ADHFE1,PRRC2C,VPS13A,SYP,ANKRD12,TBCEL,TCF4,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,R3HDM1,TPM1,NPL,KCNE5,TSN,TUBB2A,CLHC1,UGT8,VLDLR,ZNF19,ZNF28,TRIM9,ZNF45,NDRG4,EML6,DPYSL5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,IFT88,NETO1" MicroRNA hsa-miR-2113:mirSVR_highEffct hsa-miR-2113:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.49E-82 1.95E-78 2.96E-81 2.72E-80 205 1132 "RALGAPA1,ABR,ACADM,ACTN1,ADCY6,ADD1,BEND6,KLHL13,KCTD16,WDR35,OSBPL8,ADGRF5,PCDH10,SYT13,DPP10,LCORL,MAP4K3,PKP4,EPB41L5,CASK,RGS20,LINC00173,NUMB,EIF4G3,ATP1B3,DPY19L3,ADAM23,TTLL9,ADGRB3,SEC11C,GPR146,SYNJ1,CACNA1B,CACNB4,CAMK2G,SLC25A14,SPAG9,CDH2,MAGI1,C4orf33,AKAP6,ABI3BP,TBPL1,ZNF521,ZNF385A,CRHBP,HAPLN1,ANKRD44,CS,CSNK1E,SOCS5,FAM169A,DOCK4,HDAC9,RIPOR2,ZFYVE16,LIN54,BRINP1,AIF1L,DBN1,ELMO1,GOLT1B,EBF1,EDIL3,EDN1,ANKRD46,SUGP2,AASS,EIF4G2,STARD3NL,NCALD,EYA1,MRVI1,ABCA8,SH3YL1,TAOK3,SLC9B2,FER,FGF12,FGF13,POLK,SYNCRIP,SLC37A3,NELFCD,UFM1,ZNF605,STAU2,AP4B1,FYB1,GALNT15,KIAA1841,MSTN,ARFIP1,AHDC1,MALT1,RAB30,AIFM3,ZNF638,FERMT2,GPD2,PRUNE2,PLCD4,ZBTB49,HLF,IDH3A,RBPJ,ZNF678,KCND1,KCND2,KCNN2,STXBP5,HECTD2,LRP1B,MEIS2,MITF,MXI1,NDP,IDNK,NRCAM,IGSF11,PCSK5,NLGN3,PIK3C2A,ZNF655,CCSER2,RETREG1,MTRF1L,PURG,PDZRN4,TRHDE,STRN3,SH3KBP1,EPDR1,HYDIN,RELN,CNTLN,BDNF-AS,OXR1,CRTAC1,GTDC1,CARF,ROBO2,FBXW7,ATP8B4,SGSM1,KCNIP1,FAM192A,SEMA6D,SATB1,CSRNP3,SCN8A,SEC14L1,KIF16B,CPEB3,SHC4,SLA,SEPHS1,CCDC88A,LIMCH1,ANKFN1,KDM4C,ZBTB43,RBM26,LMO3,POGZ,ERBIN,MPRIP,RGL1,SULF2,STXBP1,NECAB1,SYT1,MMS19,ANKRD12,CAMTA1,TAL1,ALG1,ADGRL3,TCF4,TRIM2,TCF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,ACTR6,KAT6B,SYNPO2,UGT8,VSNL1,RBFOX3,RICTOR,ZBTB14,TRIM9,ZBTB38,UPF3A,RNF103,NAV3,KAT6A,DPF3" MicroRNA hsa-miR-575:mirSVR_lowEffct hsa-miR-575:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.60E-82 2.57E-78 3.89E-81 3.58E-80 226 1376 "RALGAPA1,KCNH8,ASPHD1,ACADM,KDM5D,TMCC3,ADD2,AP2A2,PCDH19,KIAA1324,CC2D2A,OGT,LRCH2,EP400,PARG,TNRC6C,ZFYVE28,CCDC74A,NUMB,INSYN2B,SLC4A4,ATP2A2,SLC2A11,ATP6V1G2,BBS2,RGS9,NRP2,BID,BMP7,SYNJ2,MYRF,CFAP410,CACNA2D1,HAP1,CAMK2A,CH25H,PRC1,CLDN10,LRBA,CBARP,SOCS6,NDST3,CPNE6,NRXN3,PLAA,NGEF,HECTD1,IGLON5,BAG4,MYRIP,SLC35F1,CRMP1,HAPLN1,CRY2,SEC24C,ARHGEF10,RIMS4,PDE4DIP,PLXNA4,RASGEF1C,PUM1,DOCK4,ARHGAP32,DCAF8,INTS1,ARMCX2,YTHDC1,DGCR5,ZBTB24,MYEF2,KIAA0753,PLPPR4,SGSM2,FAM107B,KIF19,SLC12A6,DRP2,PDCD6IP,DTNA,DNM1L,EDN1,PHC2,ANKRD46,EIF5,VPS13B,SRRM1,PIPOX,MRVI1,PTK2B,FDFT1,POLR1B,PRKAG2,HPCAL4,AGAP2,IQCG,NBEA,ERGIC3,TVP23A,MEGF10,HRASLS5,CHL1,B4GALNT1,ZNF274,DISC1,ARFIP1,USP19,GLI2,MAP7D2,DCLK2,GPD2,FUT10,STON1,DIDO1,SERP2,ATOH8,RASSF8,TNFAIP8L3,VSIG4,HNF4G,NEGR1,ZNF678,KCND1,KIF5A,LAMP2,STMN1,LMO2,CLEC18A,MAP2,MAP4,MARK1,SAMD5,N6AMT1,NEK1,CNOT4,NOVA1,NPTX2,NTRK2,ENPP2,PFKFB3,GPSM2,LRP12,EXOSC10,ING3,POLR2F,MASP1,KLK6,BCAS3,CNTLN,PTPRE,PTPRG,PTX3,USP47,NWD1,MORC4,GTDC1,RGS3,RGS4,SLC25A36,RIC8B,PNMA8A,BAALC,ADAL,RPS6KA2,MAP6D1,ZNF354C,DGLUCY,SATB1,SCN2B,SCN8A,FNIP1,TNFRSF19,CASC3,RASA3,KIF16B,ASAP3,CPEB3,CNKSR2,PREX2,SLC2A5,WDR47,ATF7IP,SLC22A4,RCOR3,INAVA,SNRPN,TMCC1,FNBP1,DOK5,CLASP2,PLCB1,SYT1,EXOC7,NEU4,ZFP90,TPCN2,DOCK9,RNF216P1,DNAH7,SIRT1,AP4E1,ARL10,TIAM1,FAM124A,TPM2,SMUG1,TRIO,AMACR,STXBP4,XPO1,XRCC4,ZNF24,ZNF142,ZBTB38,ANKS1B,ZFAND5,EMSY,EVI5,LINC02210,RNF103,URM1,KCNAB1,PCBP4,FZD3,HNRNPA3,PHTF2,FXR1" MicroRNA hsa-miR-454-3p:TargetScan hsa-miR-454-3p TargetScan 5.17E-82 2.89E-78 4.33E-81 3.99E-80 165 721 "NCKAP5,NDRG2,CCDC85A,KIAA1211,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,NCOA1,INSYN2B,ATP2B2,FUBP1,LDLRAD4,CALB1,KALRN,PTBP2,CAST,RUNX1T1,CFL2,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,COL9A3,SEC31B,CLOCK,GDA,CSF1,LRIG1,IPCEF1,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,DNAL1,KLHL3,FAM107B,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,ENPP6,RAB9B,ERBB4,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,FUT9,MPP6,FYN,IQGAP2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,GRB10,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,CDH20,KCNB1,KCNN3,KIT,MAP4,MARK3,MBNL1,CHIC1,LRP1B,AFF1,MYT1,NOVA2,NPTX1,PAX6,PDE4D,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,POU6F1,PPP2R5E,PRKACB,PSD,MTMR10,PTPRD,PTPRG,RASGRF2,RBBP8,RDX,FIGN,KLHDC8A,ROBO1,ROBO2,RORB,CLIP1,RTN1,RXRA,SATB1,ATXN2,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,ERC1,CDK19,DIP2A,NUDT10,PLCB1,ANKRD28,ANKRD12,FBXW11,SATB2,DICER1,NACC2,R3HDM1,CSMD1,FAM155A,REEP1,FSTL5,MAP3K12,CADM2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-130b-3p:TargetScan hsa-miR-130b-3p TargetScan 5.17E-82 2.89E-78 4.33E-81 3.99E-80 165 721 "NCKAP5,NDRG2,CCDC85A,KIAA1211,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,NCOA1,INSYN2B,ATP2B2,FUBP1,LDLRAD4,CALB1,KALRN,PTBP2,CAST,RUNX1T1,CFL2,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,COL9A3,SEC31B,CLOCK,GDA,CSF1,LRIG1,IPCEF1,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,DNAL1,KLHL3,FAM107B,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,ENPP6,RAB9B,ERBB4,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,FUT9,MPP6,FYN,IQGAP2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,GRB10,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,CDH20,KCNB1,KCNN3,KIT,MAP4,MARK3,MBNL1,CHIC1,LRP1B,AFF1,MYT1,NOVA2,NPTX1,PAX6,PDE4D,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,POU6F1,PPP2R5E,PRKACB,PSD,MTMR10,PTPRD,PTPRG,RASGRF2,RBBP8,RDX,FIGN,KLHDC8A,ROBO1,ROBO2,RORB,CLIP1,RTN1,RXRA,SATB1,ATXN2,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,ERC1,CDK19,DIP2A,NUDT10,PLCB1,ANKRD28,ANKRD12,FBXW11,SATB2,DICER1,NACC2,R3HDM1,CSMD1,FAM155A,REEP1,FSTL5,MAP3K12,CADM2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-130a-3p:TargetScan hsa-miR-130a-3p TargetScan 5.17E-82 2.89E-78 4.33E-81 3.99E-80 165 721 "NCKAP5,NDRG2,CCDC85A,KIAA1211,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,NCOA1,INSYN2B,ATP2B2,FUBP1,LDLRAD4,CALB1,KALRN,PTBP2,CAST,RUNX1T1,CFL2,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,COL9A3,SEC31B,CLOCK,GDA,CSF1,LRIG1,IPCEF1,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,DNAL1,KLHL3,FAM107B,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,ENPP6,RAB9B,ERBB4,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,FUT9,MPP6,FYN,IQGAP2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,GRB10,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,CDH20,KCNB1,KCNN3,KIT,MAP4,MARK3,MBNL1,CHIC1,LRP1B,AFF1,MYT1,NOVA2,NPTX1,PAX6,PDE4D,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,POU6F1,PPP2R5E,PRKACB,PSD,MTMR10,PTPRD,PTPRG,RASGRF2,RBBP8,RDX,FIGN,KLHDC8A,ROBO1,ROBO2,RORB,CLIP1,RTN1,RXRA,SATB1,ATXN2,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,ERC1,CDK19,DIP2A,NUDT10,PLCB1,ANKRD28,ANKRD12,FBXW11,SATB2,DICER1,NACC2,R3HDM1,CSMD1,FAM155A,REEP1,FSTL5,MAP3K12,CADM2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-301a-3p:TargetScan hsa-miR-301a-3p TargetScan 5.17E-82 2.89E-78 4.33E-81 3.99E-80 165 721 "NCKAP5,NDRG2,CCDC85A,KIAA1211,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,NCOA1,INSYN2B,ATP2B2,FUBP1,LDLRAD4,CALB1,KALRN,PTBP2,CAST,RUNX1T1,CFL2,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,COL9A3,SEC31B,CLOCK,GDA,CSF1,LRIG1,IPCEF1,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,DNAL1,KLHL3,FAM107B,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,ENPP6,RAB9B,ERBB4,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,FUT9,MPP6,FYN,IQGAP2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,GRB10,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,CDH20,KCNB1,KCNN3,KIT,MAP4,MARK3,MBNL1,CHIC1,LRP1B,AFF1,MYT1,NOVA2,NPTX1,PAX6,PDE4D,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,POU6F1,PPP2R5E,PRKACB,PSD,MTMR10,PTPRD,PTPRG,RASGRF2,RBBP8,RDX,FIGN,KLHDC8A,ROBO1,ROBO2,RORB,CLIP1,RTN1,RXRA,SATB1,ATXN2,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,ERC1,CDK19,DIP2A,NUDT10,PLCB1,ANKRD28,ANKRD12,FBXW11,SATB2,DICER1,NACC2,R3HDM1,CSMD1,FAM155A,REEP1,FSTL5,MAP3K12,CADM2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-301b-3p:TargetScan hsa-miR-301b-3p TargetScan 5.17E-82 2.89E-78 4.33E-81 3.99E-80 165 721 "NCKAP5,NDRG2,CCDC85A,KIAA1211,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,NCOA1,INSYN2B,ATP2B2,FUBP1,LDLRAD4,CALB1,KALRN,PTBP2,CAST,RUNX1T1,CFL2,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,COL9A3,SEC31B,CLOCK,GDA,CSF1,LRIG1,IPCEF1,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,DNAL1,KLHL3,FAM107B,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,ENPP6,RAB9B,ERBB4,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,FUT9,MPP6,FYN,IQGAP2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,GRB10,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,CDH20,KCNB1,KCNN3,KIT,MAP4,MARK3,MBNL1,CHIC1,LRP1B,AFF1,MYT1,NOVA2,NPTX1,PAX6,PDE4D,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,POU6F1,PPP2R5E,PRKACB,PSD,MTMR10,PTPRD,PTPRG,RASGRF2,RBBP8,RDX,FIGN,KLHDC8A,ROBO1,ROBO2,RORB,CLIP1,RTN1,RXRA,SATB1,ATXN2,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,ERC1,CDK19,DIP2A,NUDT10,PLCB1,ANKRD28,ANKRD12,FBXW11,SATB2,DICER1,NACC2,R3HDM1,CSMD1,FAM155A,REEP1,FSTL5,MAP3K12,CADM2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-487a:mirSVR_highEffct hsa-miR-487a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.41E-82 3.02E-78 4.53E-81 4.17E-80 195 1025 "CLK4,NCKAP5,ACTN1,PWWP2A,AP2A2,HECW2,AGT,NME5,OSBPL6,ARHGAP20,CDC42BPA,FGD2,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,PPP4R4,RGS20,STK33,NUMB,RASL11B,SLC4A4,SEC11C,CFLAR,CALB2,PTBP2,CCK,LDB2,ZMYM4,MAGI1,RCBTB2,SRSF11,NGEF,ABCG2,TMEM184B,SULT4A1,CNR1,COL9A1,CRHBP,GDA,TRIM69,SLITRK5,APPL1,DOCK4,GAPVD1,LIN54,KIAA0586,DAPK1,YTHDC1,ZBTB24,MYEF2,ZC3H11A,PLPPR4,SGSM2,USP3,CPEB2,CASP8AP2,PDCD6IP,DTNA,DNM1L,GOLT1B,HIPK3,FAM13A,PHF20L1,MRO,GPHN,SRRM1,MRPL10,SIRPB1,ABCA8,TAOK3,CEP78,GORAB,SUCO,MEX3B,VTI1B,GALC,NEU3,TUBA8,PPARGC1A,COPS8,ZNF638,LNX1,GPD2,TDRKH,PSIP1,HNMT,SMAP1,ZIC5,LRRCC1,INSM1,KCNN2,KIT,HECTD2,MARK3,MEIS1,MEST,AFDN,NELL2,NF1,LOC100128398,CLDN11,ETFRF1,PDE4D,SNX10,KCTD15,PDZRN4,EPB41L4B,DRAM2,PPM1B,PPP2R5E,PRKACB,PKIA,PRPSAP2,DCHS2,SNRK,MTMR10,PTPN13,EML5,MARCH1,CEP97,OXR1,RASGRF2,RBBP6,ZDHHC14,RDX,MORC4,RFX3,TMLHE,CARF,PCMTD2,ZC3H14,HUNK,ZNF568,AP1AR,ATXN2,FNDC3A,WDR37,FAM81A,CCDC88A,SLC9A5,ANKRD36,LIMCH1,MBD5,SNRPN,PDZD2,CDK19,MCF2L2,ERBIN,ZSCAN29,NEK4,SEPT8,NSFL1C,NECAB1,SYNE2,ARHGEF9,VPS13A,NUDT10,SYPL1,COBL,MTCL1,PJA1,MLST8,TAF9,ADGRL3,ZEB1,RPGRIP1L,PUM2,SIRT1,ITGB3BP,AP4E1,AKTIP,TP53BP1,CDK20,RUNDC3B,STXBP4,RUSC1,KCNE5,SGK3,UGT8,ZFP37,ZNF711,ZNF19,ZNF32,KCNT2,FSTL5,EML6,ANKS1B,SMARCAD1,SLC30A4,EVI5,TMEM178A,TRIM16L,FAM13C,PHTF2,JMJD1C" MicroRNA hsa-miR-186:PITA hsa-miR-186:PITA_TOP PITA 6.45E-82 3.61E-78 5.40E-81 4.97E-80 174 809 "CLK4,NDRG3,KLHL32,ADD1,PWWP2A,ZNF608,INTS2,OSBPL8,CDC42BPA,DPP10,LRCH2,MAP4K3,USP37,RGS20,CADPS,ZBTB10,CALB1,VXN,CAST,MTMR7,C1orf52,LRBA,SEPT7,DLGAP2,CHGB,SOCS6,CNOT8,FHL5,ZNF385A,AKAP12,CNTNAP2,RIMS2,KIAA0408,ZFYVE16,LONRF1,YTHDC1,ZC3H11A,SNAP91,GRIN3A,NR1D2,CDON,CPEB2,PDCD6IP,FRY,YAF2,FAM13A,MBNL2,TENM1,PLEKHA1,TMEM35A,PAN3,EPHB1,SRRM1,ERBB4,EYA1,ACSL4,PTK2B,DLC1,SEC24B,MEX3B,AGAP2,SYNCRIP,SEMA4D,NBEA,KHDRBS3,CELF1,STAU2,GABRB3,TNRC6A,GRIA2,C1QL4,FICD,ZHX1,BACH2,MIER3,NEGR1,AGFG1,ZIC5,INSM1,KCND2,STXBP5,SMAD1,MAP2,MAP4,MBNL1,CHIC1,MITF,MXI1,MYT1,CNOT4,IGSF11,GPR137C,PDE4D,GPR85,PFKFB4,PIK3C2A,ZNF655,RETREG1,MAPKAP1,LRP12,EPB41L4B,PPP2R2C,PPP3CA,PPP3CC,DIRAS2,RELN,PTPRO,PID1,USP47,ZMAT4,GTDC1,FIGN,ZFHX4,HUNK,NCBP3,SALL1,SEMA6D,SATB1,SCN8A,FNIP1,SMPD3,RASA3,SCAF8,FERMT1,CPEB3,CHD9,FNDC3A,ABLIM3,BTBD3,EPN2,TRIM67,SLC12A2,CPEB4,SNAP25,MBD5,FAM126B,SOX11,SP4,PEG10,ARHGAP26,CDK19,RBM26,LMO3,CLASP2,NECAB1,ARHGEF9,ANKRD12,CAMTA1,TAL1,TCF4,DMXL2,ZFP90,NSD1,PUM2,SIRT1,HEY1,TPM1,DOK6,TRPS1,TSN,FAM155A,UBE3A,WIPF1,ZNF711,CADM2,PRDM10,KCNAB1,WNK3,FZD3,PHTF2,FXR1,SOCS4,SENP7,JPH3" MicroRNA hsa-miR-582-3p:mirSVR_lowEffct hsa-miR-582-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.60E-82 3.69E-78 5.51E-81 5.08E-80 234 1475 "ACHE,KIAA1211,BEND6,DPY19L2P4,ZNF608,KCTD16,OSBPL8,FAM135A,CDC42BPA,DPP10,SUGT1P4-STRA6LP-CCDC180,SFMBT2,CADPS,CDK13,CHID1,SLC4A4,STX16,SLC2A11,RNF182,PROM1,JAZF1,IL33,CFAP410,THSD7A,CBR1,ZMYM4,TIGD7,NOG,CACNA2D2,CFL2,SRSF11,NDST3,FBXO7,MAP4K4,CNN3,PCYT1B,COL4A5,LETMD1,SLC4A8,RCHY1,GDA,RGS6,OSBPL3,APPL1,PPP6R2,DCAF4,CYBB,MYADM,RASSF2,MATR3,AIF1L,ZBTB24,FBXL5,MTX3,SEC16A,DMD,DYNC1I1,DPYSL2,RCAN1,ABCC5,EDN3,SEMA3D,TMTC1,YAF2,KMT5B,GOLGA7,ASB3,KCTD3,EIF4G2,PLEKHA1,ING4,KATNAL1,CLVS1,ZNF461,RACK1,FKTN,MED12L,POLK,MEX3B,PCYOX1,SYNCRIP,AGAP3,FOXO3,FLT1,EFCAB2,ERGIC3,KHDRBS3,CELF1,NSG1,AP4B1,MEGF11,GABRB3,GALC,ERAP1,ZNF559,KIAA1841,CPLX1,NEU3,TUBGCP4,TUBA8,ADAM28,BRD8,TOX3,ZNF638,KDM2B,LNX1,GPD2,GPR12,PCLO,SPACA9,CLASRP,PSIP1,ADAMTS6,HAS2,ZHX1,USP51,HSF2,LRRC75A,SMAP1,FAM69A,INPP5B,KCND1,GPR62,KCNJ16,MAP2,MAT2A,XRRA1,N6AMT1,MYO6,MYO9A,CCDC13,NOVA1,DNHD1,SMIM11A,NTRK2,P2RY1,PCDH9,PRTG,PDE4D,NLGN3,PIK3C2A,ZFYVE21,MTRF1L,ING3,MINDY2,PPP2R2B,PKIA,MAPK4,PTCH1,PTK2,PTPN13,PTPRE,PTPRG,TMEM231,PPP2R3C,FAT4,NWD1,RADX,RDX,ZMAT4,GTDC1,SLC25A36,ROBO2,CCDC102B,RPL15,ZC3H14,RPS20,ZNF331,SALL1,MRAS,KIF27,PPP4R3A,CCDC88A,SLC9A5,COA1,MBD5,TMCC1,ZSWIM8,SP4,HECW1,ZNF423,DBNDD2,CDK19,ITPRID2,NKAIN2,NXT2,CEP68,KANK1,NECAB1,DNAJC9,COBL,CAMTA1,TAF6,DNMBP,TBCEL,ZFP90,ZEB1,TRIM2,DOCK9,PCDHB9,PUM2,HIF3A,RNF216P1,DICER1,SIRT1,ITGB3BP,ACTR6,TP53BP2,RGMB,SYNPO2,STXBP4,TRPS1,RUSC1,CLHC1,UBE2H,MTCH1,ZNF781,CELF4,REEP1,SH3GLB2,CADM2,EVI5,LINC02210,HPS4,CIAPIN1,PDSS2,RGS7BP,KAT6A,FAM219B,ADAMTSL3,FRMD6,RNF146,SOCS4,JPH3" MicroRNA hsa-miR-340-5p:TargetScan hsa-miR-340-5p TargetScan 6.61E-82 3.70E-78 5.51E-81 5.08E-80 192 994 "CLK4,AS3MT,ADCY6,GALNT13,BRAP,RNF150,ESYT2,HECW2,OSBPL6,C1QTNF3,ALCAM,ABCD2,BEGAIN,OGT,CDC42BPA,GAS7,LGR5,IGDCC4,CASK,CDK13,NCOA1,RNF182,DPY19L3,KIF1A,JAZF1,LDLRAD4,CABP7,CALM1,CAMK2A,CAST,RUNX1T1,LDB2,KRIT1,C1orf52,DLGAP2,NOG,CFL2,CLCN3,CLTC,ARHGEF6,PCYT1B,ARMC8,MYRIP,NRG2,NSL1,FAM171B,HAPLN1,CRY2,ABCG1,LRIG1,CNTNAP2,APPL1,CTH,GREB1,PUM1,FAM131B,PYGO1,KIAA0408,ARHGAP24,MAML1,ELMSAN1,JAKMIP2,MFAP3L,KLHL3,RHOBTB1,DMD,NR1D2,CDON,DRP2,EDNRB,PLXNC1,CERCAM,RGS17,ETV1,DNAJC27,DLC1,MED12L,FGF12,ANKFY1,ATP2C1,DOT1L,CHL1,IQGAP2,NFU1,DBF4,GPR75,GLUL,LUZP2,GNAL,GPD2,GPR37,PRDM5,CIT,COQ10A,BVES,PSIP1,HNF4G,NEGR1,AGFG1,DHX35,IGF1,IL6ST,FAM69A,INSM1,C2CD4C,KCNB1,KCNJ16,KCNQ3,KIF2A,KIT,LIFR,LIMS1,MAT2A,MATN3,CHIC1,LRP1B,MID1,MITF,DBNL,MXI1,MYO9A,NFE2L2,NFYA,NPTX1,NPTX2,IGSF11,OCRL,CLDN11,PCSK1,PCSK5,PDE3A,PIK3C2A,KCTD15,PLCD1,PLCL1,LRP12,SDK2,FA2H,KANSL1,GRAMD1C,CNNM2,PTPRB,PTPRG,NKAIN1,RBBP6,RBBP8,REV3L,FIGN,RGS4,NUDT11,RNH1,RORB,MCMBP,AP1AR,SATB1,FNIP1,HSPA4L,CPEB3,PREX2,EPN2,FAM214B,PKNOX2,ARHGEF40,ATF7IP,MAPKBP1,KIF13A,BDP1,DDN,CLSTN2,NECAB1,ANKRD28,ANKRD12,DNMBP,PUM2,AP4E1,GPR161,ICAM5,KAT6B,RGMB,NR2C2,ELP5,FLRT2,EVI5,RNF103,KCNAB1,RGS7BP,FZD3,HNRNPA3,MSRB3,FRMD6,NETO2,GAN" MicroRNA hsa-miR-606:mirSVR_lowEffct hsa-miR-606:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.89E-82 3.86E-78 5.74E-81 5.28E-80 224 1355 "SYS1,TMCC3,ADD1,PLEKHH1,USP31,BEND6,KLHL13,OSBPL1A,TBC1D14,OSBPL8,ZNF578,DPP10,USP37,CDC14B,TMEFF1,ARNTL,NUMB,SLC4A4,BACH1,MPDZ,BMPR1B,ARHGEF7,NAE1,SCAPER,MTMR2,JAZF1,CACNB4,MTMR7,C1orf52,LRBA,CDH2,DCLK1,ZMYM4,DLGAP2,SRSF11,CHN2,CNOT8,RAB28,DGCR9,CLTC,QKI,COL4A5,ABI3BP,RCHY1,FAM171B,CREM,AKAP12,RNF14,TRIM69,SNCAIP,OSBPL3,DOCK4,GAPVD1,ZFYVE16,TBC1D5,DGKB,DAPK1,AIF1L,YTHDC1,MYEF2,MFAP3L,FBXL5,SV2B,DMTF1,ARRDC4,ABCC5,GOLT1B,E2F5,HIPK3,RASGRP1,SEMA3D,YAF2,PHF20L1,APH1A,EGFR,ASB3,EIF5,COPS4,C8orf37,ENPP6,NCALD,KATNAL1,NSRP1,ACSL4,SUCO,MEX3B,PCYOX1,ANKFY1,SLC37A3,C2orf88,ATP6V1H,OGA,GABRB3,GABRG1,ZNF234,SIGLEC8,PCDH17,DBF4,KIAA1958,LUZP2,PRUNE2,STON1,GRIA2,GRM2,BTN2A1,HLF,LRRC75A,SHISAL1,LRRCC1,IL6ST,METTL21A,KIF5A,STXBP5,SYTL4,HECTD2,CHIC1,KCTD6,KITLG,MYCN,NEXMIF,ZC3H12B,NF1,ALDH1L2,NOVA1,SLC11A2,NTRK2,OPA1,PIK3R1,CCSER2,TRHDE,DRAM2,PPP3CA,PRKACB,GRAMD1C,QRICH1,CNTLN,TMEM260,STK32A,PTX3,STRC,NWD1,ERI2,RGS12,RIC8B,RNASEL,ZFHX4,CCDC82,RORB,RPL15,ZNF671,MCMBP,RTN1,SALL1,SEMA6D,CSRNP3,TNFRSF19,GALNT10,SUPT20H,PPM1E,FERMT1,CHD9,FBXO11,CNKSR2,SEC31A,NUBPL,PREX2,SLC8A1,SLC12A2,NAPB,CPEB4,CXXC4,RCOR3,MBD5,SNRPN,FAM126B,SOX11,SP4,RBM26,SULF2,SYPL1,COBL,ZEB1,TPCN2,TRIM2,CLASP1,SYNE1,DOCK9,PCDHB3,NSD1,PUM2,GPRIN3,DICER1-AS1,ZFPM2,ZNF106,TMEM9,RGMB,STXBP4,TRPS1,ANKRD20A2,TTTY15,ZKSCAN5,CLHC1,UBE3A,PLEKHH2,TBC1D15,ZNF24,ZNF45,LYPD6,REEP1,DPYSL5,ANKS1B,SPIRE1,UPF3A,CADM2,EVI5,RNF103,WNK3,PDSS2,UBE3B,HNRNPA3,ADAMTSL3,TIGD6,DPF3,SOCS4" MicroRNA hsa-miR-150*:mirSVR_highEffct hsa-miR-150*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.96E-82 3.90E-78 5.79E-81 5.33E-80 188 952 "KCNH8,PWWP2A,OLMALINC,HECW2,TXNDC16,ADGRF5,CEP126,ABCD2,FAM135A,TMEFF1,CADPS,DPY19L3,ADAM23,KSR1,SYNJ2,ARHGEF7,CA8,KRIT1,METTL6,SLC16A4,ENTPD6,DGKI,ARHGEF2,CDH2,DLGAP1,SRSF11,PPT2,CLCN3,ABCG2,QKI,CNTN1,COL9A1,LETMD1,SLC4A8,COX4I1,ZNF521,CS,SNCAIP,SEC24C,ARHGEF10,SUSD5,DOCK4,ARHGAP24,LONRF1,DAPK1,ZBTB24,FBXL5,ALKBH8,PLPPR4,SV2B,DMTF1,DNAJB6,EGR3,STARD3NL,CALCRL,GPHN,NCALD,CLVS1,FAM198B,ZNF461,FER,PRKAG2,POLK,NBEA,PDLIM5,CELF1,GAD1,GATM,ARFIP1,ADAM28,PCDH17,COPS8,ZNF638,POLL,GNAL,LOXL3,CNTRL,RABL2A,MIER3,ZDHHC15,SMAP1,ZIC5,IL12A,LRRTM1,ITGAM,KCND2,KPNA5,IPO5,STXBP5,LAMP2,SYTL4,HECTD2,MITF,AFDN,MN1,ZNF92,MXI1,LOC100128398,OXTR,GPR137C,ZNF827,PCSK5,PDE4D,ENPP2,PDPK1,FAM98B,PIK3C2A,XRN1,FAM216A,JAKMIP1,STRN3,EPB41L4B,PPP2R5E,PRKCB,PTK2,PTPRN,PTPRO,ENOX1,OXR1,MSANTD2,REV3L,RGS3,KCTD17,SUGCT,CARF,ELP2,PCMTD2,NEK11,MCMBP,RYR3,SARS,SCN8A,SEC14L1,FBXO11,FHOD3,NUBPL,EPN2,CCDC88A,ELMO2,SLC22A4,ZFP1,OGDHL,INTS9,MBD5,SNRPN,FAM126B,TROVE2,SSTR1,CEP68,TTBK2,SEPT3,STXBP1,NECAB1,FBXW11,KLHL4,TCEA1,SYNE1,DOCK9,SIK3,TEK,DICER1-AS1,ITGB3BP,TIAM1,TMPO,BEX4,CSMD1,RGMB,UBE3A,PCDH20,ZIC1,ZNF708,ZNF23,KCNT2,TRIM9,ANKS1B,UPF3A,CADM2,ADAMTS9,MDH1B,GAL3ST3,NAV3,FAM13C,DOCK8,JMJD1C,TRAM2-AS1,RNF170,IFT88,NETO2" MicroRNA hsa-miR-28-3p:mirSVR_lowEffct hsa-miR-28-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.48E-82 4.74E-78 7.04E-81 6.48E-80 213 1228 "CLK4,ADCY6,GALNT13,ADD1,ESYT2,OSBPL1A,TBC1D14,WDR35,TXNDC16,CEP126,MARCH4,UNC79,FAM135A,MAP4K3,APBB2,MAGEE2,TMEFF1,DPY19L3,BACH1,DST,SYNJ2,BTK,WASF1,CACNB4,CALB1,RUNX1T1,CBLN1,USP6,LRBA,LRRFIP1,CLGN,SRSF11,FOXN3,SOCS6,TAOK2,TPP1,QKI,MAP4K4,AKAP7,PCYT1B,FAM149A,AKAP6,AKAP5,CREM,AKAP12,OSBPL3,SIPA1L1,FAM169A,CCDC144A,HDAC9,LONRF1,MATR3,DGKG,ARMCX4,PLPPR4,SV2B,WDR20,FAM107B,GRIN3A,USP3,NR1D2,RCAN1,E2F5,EIF4G2,NCALD,DNAJC27,ABCA8,FAM198B,RACK1,ZNF589,POLK,MEX3B,FOXF2,C2orf88,PDLIM5,KHDRBS3,CELF1,AP4B1,HRASLS5,GABRA3,GABRB3,GABRG1,GALC,ZNF274,ZNF559,DISC1,PPARGC1A,TCERG1,GLYR1,CLASRP,RNF165,RABL2A,SOX21,PSIP1,ADAMTS6,GUCY1B1,ZHX1,MIER3,VSIG4,ZDHHC15,NEGR1,SHISA6,SMAP1,IGF1,GAREM2,SCIN,JAK2,STXBP5,LIG4,MAP2,MATN2,KITLG,SAMD5,MYO6,MYO9A,NDP,NEK1,NOVA1,LOC100128398,P2RY1,CNTN3,PAX6,PCSK1,SLC10A4,PFKFB2,CCSER2,ZFYVE21,XRN1,PLIN1,PURG,PDZRN4,STRN3,LRP12,ING3,EPB41L4B,PPARA,PPP2R5E,PRKAB2,PRKACB,HYDIN,QRICH1,TUG1,CEP97,RASGRF2,KHDRBS2,ZDHHC14,PBRM1,RNASEL,TMLHE,CARF,ROBO2,CCDC25,ARMH4,ADAL,CLIP1,SCP2,GALNT10,KIF27,TRA2B,COPZ1,HSPA4L,ARX,CPEB3,FBXO11,FNDC3A,CNKSR2,WDR37,PPP4R3A,SLC12A2,RCOR3,MBD5,BDP1,SOX11,KDM3A,SP4,NMNAT2,TEX2,ZC3H13,CLSTN2,NXT2,SEPT3,KLHL7,SUPT5H,PRRC2C,NUDT10,TACR1,ADGRL3,MGRN1,DMXL2,ZEB1,CLASP1,DOCK9,SIRT1,NPL,ZNF346,PDSS1,TRPS1,DCBLD1,ANKRD20A2,TSC1,GORASP1,OSBP2,PLEKHH2,WIPF1,XPO1,XRCC4,ZIC2,NDRG4,SPIRE1,CADM2,RGS7BP,DNAH10,SOCS4" MicroRNA hsa-miR-137:TargetScan hsa-miR-137 TargetScan 9.16E-82 5.12E-78 7.59E-81 6.99E-80 187 943 "ABHD6,NCKAP5,FMNL2,ELFN2,RNF157,PWWP2A,RNF150,BEND6,INTS2,MTUS1,HECW2,OSBPL8,PITPNM2,CDC42BPA,CADPS,NCOA1,INSYN2B,ATP2A2,ATP2B2,ADAM23,BACH1,HCN2,BMP7,CACNA1I,CACNA1G,LDLRAD4,CAMK2A,HIP1R,CBFA2T2,KCNAB3,L3MBTL4,CLGN,CFL2,FOXN3,NRXN3,FAM19A5,QKI,IGLON5,BAG4,NRG2,C2CD2,ANKRD44,OSBPL3,CSNK1G3,RIMS4,PPP1R16B,GREB1,PPP6R2,PYGO1,DCAF8,LIN54,MAML1,DGKG,DNAL1,DBN1,JAKMIP2,KLHL3,RHOBTB1,PDCD6IP,E2F6,EDIL3,FRY,EGFR,MBNL2,EIF4G2,EIF1,RCAN2,ERBB4,CEP85L,FGF11,NBEA,CAMKK2,NSG1,FUT9,MPP6,MEGF11,CPLX1,CSDC2,PPARGC1A,KIAA1958,LUZP2,DCLK2,GPD2,CACFD1,GRM2,RNF165,ATOH8,RASSF8,BACH2,MIER3,HLF,NEGR1,RBPJ,C2CD4C,CDH20,KCNB1,KCND1,KCND2,KIT,LIFR,PAXBP1,MARK1,MARK3,CHIC1,MEIS1,MITF,MSI1,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,CNTN3,PDE3A,PDE4A,PDE4D,PDE1B,LRP12,LRRN3,PPP5C,PRKAB2,MAPK10,FITM2,DIRAS2,DCHS2,ELOVL2,PTN,PTPRD,NKAIN1,OXR1,RASGRF1,MSANTD2,GTDC1,RIC8B,RORB,RPL15,FBXW7,RYR3,ATXN7,SCN8A,FNIP1,PPM1E,CPEB3,CHD9,FAM81A,LGI3,CXXC4,ABTB1,LIMCH1,MBD5,FAM126B,PDZD2,BDP1,CDK19,NFASC,CLASP2,NXT2,PLCB1,ANKRD28,ANKRD12,MGRN1,SATB2,RPGRIP1L,GPRIN3,ENHO,NACC2,RELL2,CSMD1,DOK6,OSBP2,BCL2L13,MGAT5B,RICTOR,EML6,CADM2,FAM47E,RGS7BP,MARCH8,HNRNPA3,PHTF2,MSRB3,FRMD6,NETO1,GAN,PRRT4" MicroRNA hsa-miR-513b:mirSVR_highEffct hsa-miR-513b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.17E-82 5.13E-78 7.59E-81 6.99E-80 214 1240 "ACADM,KLHL32,CCDC85A,PTCHD1,AGT,CC2D2A,HFM1,ADGRF5,ALCAM,FAM135A,SYT13,AMPD3,LRCH2,PARG,LGR5,ARRB2,ATP1B3,ATP6V1G2,BACH1,BBS2,DST,SYNJ1,ARHGEF7,SCAPER,WASF1,LURAP1,PTBP2,SPAG9,RUNX1T1,SLC16A4,C1orf52,LRBA,ZMYM4,CDO1,DLGAP1,CCPG1,CHN2,RAB33A,NRXN3,TPP1,IQCK,COL9A1,TBPL1,AHCTF1,IGDCC3,SLC35F1,CRMP1,ABCG1,ARHGEF10,CSNK1G3,SOCS5,DZIP3,PHF14,RIMS2,FAM131B,BOC,DOCK4,HDAC9,GAPVD1,ARHGAP24,DCTN1,ZNF804A,DDX46,PLPPR4,FAM107B,KIF19,DLX1,RPS6KL1,DPH1,DTNA,DNM1L,E2F6,CALCRL,RASGRP2,STX2,SRRM1,DENND4A,ADGRV1,SH3YL1,TAOK3,DLC1,GORAB,FGF1,VTI1B,ANKFY1,EFCAB2,SPECC1,UFM1,USP21,FYN,GAD1,KIAA1841,NEU3,ARFIP1,GHR,DBF4,GLYR1,RAB30,MSL3,GPD2,KAT7,FRMD3,NEGR1,ICA1,IRF8,MSL1,ZNF678,INSM1,SLC35G1,STXBP5,SFXN5,PAXBP1,PACRG,SMAD1,MARK1,MAT2A,BLOC1S2,MYCN,LAYN,NPTX1,P2RY1,GLIPR1L2,PCSK5,PRTG,PDE4D,GPR85,PRIMPOL,PDZRN4,MAPKAP1,SCHIP1,EPB41L4B,FA2H,PPP2R5E,PPP3CA,CEP41,APTX,ELOVL2,TMEM260,CEP97,TMEM255A,FAM66C,ZNF493,RASGRF1,ZDHHC14,REV3L,ZFHX4,TMLHE,GSTCD,ELP2,PCMTD2,LRRK2,DGLUCY,MYO18A,PREX2,PPP4R3A,DHX30,KDM4D,SEPHS1,TET1,CPEB4,OGDHL,DMRTC1,TTC17,SNAP25,SNRPN,TMCC1,FNBP1,DOK5,KDM3A,MYCBP2,CDK19,CLSTN2,STAU1,ELOVL4,CEP68,RGL1,VPS13A,PLCB1,SYN2,TACC1,CAMTA1,ADGRL3,TBCEL,USP22,CLASP1,SYNE1,FRYL,SIRT1,C18orf54,AP4E1,KAT6B,NPL,TSN,TTC3,ZKSCAN5,UBE3A,UCHL1,FLRT2,TBC1D15,P2RY12,CLDND1,ZIC2,ZNF17,MICU3,MKRN3,ZBTB38,FSTL5,SMARCAD1,EMSY,CADM2,ADAMTS9,NAV3,KAT6A,SENP7" MicroRNA hsa-miR-224:mirSVR_highEffct hsa-miR-224:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.26E-81 7.04E-78 1.04E-80 9.58E-80 206 1151 "KLHL32,TMEM132B,ADCY6,BEND6,PCDH10,AMPD3,APBA2,USP37,DNAH17,RASL11B,SLC4A4,ATP1B3,ZNF582,DPY19L3,TTLL9,SEC11C,BID,BMPR1B,ST3GAL5,CACNA1B,KALRN,CAST,NFS1,CCPG1,CHN1,MAP4K4,ARMC8,AKAP6,LETMD1,ZNF521,IGDCC3,NCOR1,CSNK1E,PDE4DIP,USP6NL,KCTD8,TMEM170A,GIT2,ARMCX2,MYEF2,FBXL5,RHOBTB1,WDR20,KIF19,SEC16A,DNM1,USP3,CPEB2,DPYSL2,DTNA,MAMLD1,EDIL3,EDNRB,HIPK3,FRY,FAM13A,MBNL2,EPB41L2,STX2,FAM198B,SH3YL1,ACSL4,GORAB,POLR1B,FGF14,FGFR1,SUCO,MEX3B,SEC23B,FLT1,PSD2,SLC37A3,FAM49B,ATP2C1,OGA,ERAP1,ACSS1,IGSF5,TCERG1,TNRC6A,ZNF638,GRIK4,PRDM5,PSIP1,RASSF8,ELOVL5,HMGCR,SOWAHA,RBPJ,IL6ST,NME9,ITGAM,KCND2,KCNN2,STMN1,LMO2,PACRG,MAP4,MARK1,MATN3,MBNL1,LRP1B,SRSF12,AFDN,BLOC1S2,NRBP2,LYRM9,DNHD1,NRCAM,NUCB2,GPR137C,CNTN3,PDE4D,PFKFB2,PFKFB3,PIK3C2A,PURG,STRN3,PPP3CA,KANSL1,GRAMD1C,MASP1,RELN,WBP1L,APTX,WDR25,ZSCAN32,PTX3,ZNF615,OXR1,RADX,RDX,ERI2,RGS4,SLC25A36,ZFHX4,EXD2,PCMTD2,CCDC102B,EPHA10,FBXW7,ATAT1,SCP2,CASC3,ARX,PPP4R3A,EPN2,SLC11A1,ELMO2,ATF7IP,ZFP1,PDZD2,KDM3A,ZNF423,ZBTB43,CLASP2,POGZ,NKAIN2,SS18,ELOVL4,SYNE2,NUDT10,SYT1,DNMBP,TBCEL,ZFP90,TCF12,SYNE1,NAT16,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,NPL,SYNPO2,SMUG1,AMACR,TSN,TTC3,TUBB2A,FAM155A,VLDLR,ZBTB14,TRIM9,FSTL5,SMARCAD1,EMSY,DNAH10,AMN1,MRPL47,DOCK8,RTN4,KAT6A,HNRNPA3,ACTR3B,ADAMTSL3,MSRB3,ZDHHC20,IFT88,NETO1" MicroRNA hsa-miR-193a-3p:mirSVR_lowEffct hsa-miR-193a-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-81 9.31E-78 1.37E-80 1.26E-79 216 1267 "KCNH8,ACADM,ASIC1,ACHE,CLK4,NCKAP5,ADD1,PTCHD1,SLC24A4,AP2A2,OSBPL8,PCDH10,UNC79,CDC42BPA,APC,VAT1L,BCAS1,TNRC6C,CDK10,SEMA4G,CASK,ZSCAN18,EIF4G3,DPY19L3,SYNJ1,SYNJ2,JAZF1,CAST,MTMR7,P2RX6,EVI5L,NOG,UBE2L6,CACNA2D2,TAOK2,EPS15L1,NRXN3,CLTC,ARHGEF6,AKAP6,SLC4A8,TOGARAM2,NCOR1,CS,CST3,PLXNA4,PPP1R16B,RUBCN,FAM131B,ARMCX2,RUSC2,GUCD1,MTX3,DOCK2,MAMLD1,DNAJB6,ABCC5,EDN1,HEYL,YAF2,GOLGA7,ASB3,EIF4G2,EPB41,ETV1,SIRPB1,ADGRV1,F5,SCML2,ZMYND10,FCGRT,OLFM1,FHL1,ANKFY1,PSD2,EFCAB2,GABBR1,ZNF274,ERAP1,ADAM28,CRCP,TCERG1,TNRC6A,STARD3,DIDO1,GRIN2C,PRDM5,LINC01089,FAM19A2,AP4S1,MAP4K5,ZHX1,SMAP1,ICA1,MSL1,ZNF546,FAM69A,INPP5B,ITGAM,JAK2,KCNK3,KIT,CAMK2N2,ASPRV1,CLEC18A,ZFYVE27,MGAT3,MMP16,ZNF680,RTL5,HNRNPM,NNAT,DNHD1,NRCAM,OGG1,PCDH9,PDE4D,NALCN,CCSER2,NLE1,FAM216A,PLCB2,PLIN1,PNMA3,RETREG2,EPB41L4B,POU6F1,TATDN3,CCDC144B,PRKACB,GRAMD1C,TMEM104,PTCH1,PTK2,TMEM260,PTPRE,PTPRG,PTX3,PID1,CEP97,FAM66C,IQSEC3,TRIM68,SLC25A36,PBRM1,RNASEL,RNH1,GSTCD,KIRREL1,ROBO2,EPHA10,ATP8B4,TCP11L1,CLIP1,SATB1,GALNT10,SHMT2,NLGN1,SEC31A,KANSL3,ATF7IP,LIMCH1,PDZRN3,DOP1A,ZSWIM8,HECW1,UHRF1BP1L,TSPYL2,DDN,NFASC,CLASP2,SS18,ZSCAN29,SEPT8,KANK1,STXBP1,NSFL1C,SYNE2,SYN1,TMEM150C,COBL,TAF6,EXOC7,SMG6,TCF4,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,MTMR14,TK2,LRRC8A,NPL,TPM2,ZNF346,AMACR,TRO,KCNE5,TSN,BCL2L13,VLDLR,CLIP2,CRB2,NT5M,PRDM8,RNF103,NAV3,URM1,DOCK8,KAT6A,FXR1" MicroRNA hsa-miR-892b:mirSVR_lowEffct hsa-miR-892b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-81 9.74E-78 1.43E-80 1.32E-79 244 1606 "ABR,NCKAP5,ADD1,PTCHD1,OSBPL8,CC2D2A,AK2,SPOP,ARHGAP20,ZNF687,LCORL,ARMC12,MYH7B,SEMA4G,DNAH17,CHRD,CCAR2,TMEM108,EIF4G3,ALDH7A1,DPY19L3,BACH1,PROM1,SYNJ1,GYG2,CA12,DDR1,CALM1,KALRN,CCNH,SEPT7,CDC25B,DCLK1,FOXN3,SOCS6,MS4A7,RAB28,CLTC,ABCG2,SRP14-AS1,RAB26,SUMF2,FAM171B,CLOCK,HAPLN1,GDA,CRYM,CSF1R,SEC24C,PDE4DIP,CST3,KIAA0040,DCAF4,HDAC9,RIPOR2,ZNF337,TBC1D5,LIN54,ARMCX2,SPATA2,JAKMIP2,HEPH,FBXL5,KIAA0319,KLHL3,FAM107B,RAB39B,USP3,NR1D2,DMTF1,DNM1L,EBF1,EDNRA,HIPK3,APH1A,MBNL2,KMT5B,EIF4G2,ELN,PIPOX,DNAJC27,ADGRV1,FAM198B,PTK2B,STRADA,FECH,SPSB4,IP6K2,SEMA4D,NOP56,NELFCD,CGREF1,OGA,MEGF11,MEGF10,GABRA3,DENND2A,FAM120B,GALC,B4GALNT1,RAPGEF6,ZNF274,INPP5K,GATM,PCDH17,GGT7,ZNF276,GLYR1,POLL,GRB10,SERP2,GRIN2C,AP4S1,RNFT2,ADAMTS6,SLC2A6,PADI2,FRMD5,GABARAPL2,AGBL5,MSL1,LRRCC1,SCIN,ITPKB,JAK2,KCNN2,KCNN3,A1BG-AS1,STMN1,MAP6,MARK1,MARK3,MATN3,MEF2C,SRSF12,MID1,PPM1L,POC1B,ZNF680,GIT1,MXI1,LAYN,RTL5,DNHD1,PCBP3,SLC11A2,ZNF827,PCDH9,PDE3A,PDE4D,SEMA5B,PLCD1,PLIN1,PRIMPOL,PNMA3,ANKRD16,SCHIP1,ING3,TATDN3,PPP3CA,RASGEF1B,GRAMD1C,GDPD2,CNTLN,PTCH1,ANKHD1,PTK2,TMEM260,ZSCAN32,PTPRE,ZSCAN2,TUG1,RAP1GDS1,RASGRF2,GAL3ST4,PRIMA1,PBRM1,RNH1,CARF,GSTCD,YY1AP1,ELP2,TRAPPC13,SEMA6D,SCN7A,PRCD,TNFRSF19,CASC3,TRA2B,COPZ1,SH3GL3,SHMT2,NLGN1,SEC31A,DZIP1,WDR37,ABLIM3,SLC6A8,KBTBD4,ATF7IP,CDK5RAP2,CABCOCO1,PDZRN3,SPATA7,NFASC,CLASP2,POGZ,ZNF302,ZC4H2,SEPT8,CEP68,NSFL1C,DNMBP,FAM208A,TCF12,FRYL,SIK3,TEK,FAM200B,CDH22,ARL10,ENHO,MTMR14,TIMP4,SYNPO2,TRO,RUSC1,GORASP1,BCL2L13,WIPF1,ZNF24,LYPD6,SPIRE1,EVI5,PRDM8,PRDM10,RNF103,GAL3ST3,KCNAB1,MPPE1,AMN1,MSRB3,FXR1,IFT88" MicroRNA hsa-miR-4263:mirSVR_highEffct hsa-miR-4263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-81 1.11E-77 1.64E-80 1.51E-79 214 1245 "ACADM,CLK4,NCKAP5,KDM5D,XKR4,FMNL2,ADCY8,PLEKHH1,KIAA1211,ADRB2,MTUS1,KCTD16,OSBPL8,HFM1,FAM135A,ANK2,LCORL,RGS20,PDE8B,NCOA1,RNF182,ADGRB3,SEC11C,DST,C5,RAB29,THSD7A,PTBP2,CAMK2G,SEPT7,ZMYM4,TIGD7,CFL2,B4GALT6,CNR1,ABI3BP,RTTN,MYRIP,ANKRD44,SNCAIP,ARHGEF10,CSNK1E,CSNK1G3,SUSD5,SIPA1L1,SOCS5,FAM169A,DZIP3,GREB1,DCAF4,DOCK4,HDAC9,KATNAL2,ZFYVE16,KIAA0586,PABPC5,GIT2,SPOCK3,FAM107B,NR1D2,DMTF1,TOM1,DNAJB6,DNM1L,AASDH,WDPCP,EDN1,SEMA3D,EGR3,ZNF549,ADGRV1,CLVS1,FAM198B,SH3YL1,ACSL4,CEP78,ZNF589,IP6K2,SYNCRIP,NBEA,APOPT1,PDLIM5,ATP6V1H,OGA,GABRG2,DENND2A,RAPGEF6,ZNF234,ZNF559,DISC1,GATM,ARFIP1,PPARGC1A,MSL3,KCNMB4,DCLK2,PRUNE2,ATE1,RNFT2,ADAMTS6,GUCY1B1,MAP4K5,UBE2QL1,ZHX1,ELOVL5,SYNPO,IGFBPL1,ZDHHC15,AGFG1,ZNF181,LRRCC1,TJAP1,ZNF678,NME9,SLC35G1,STXBP5,LAMP2,HECTD2,NCOA7,PIK3AP1,MAP4,MEIS1,MSR1,ZNF92,NEXMIF,ZNF862,NEK1,NF1,CNOT4,OXTR,PDE4D,SNX10,XRN1,KCTD15,GPSM2,MTRF1L,LRP12,ING3,TATDN3,RANBP3L,RASGEF1B,CEP41,GRAMD1C,SNRK,MTMR10,TMEM260,STK32A,PID1,CEP97,TMEM255A,FAM66C,SH3TC2,FAM184A,KHDRBS2,RGS3,PBRM1,SETD5,EXD2,CARF,CCDC25,RPL15,FBXW7,TCP11L1,LRRK2,ABCA11P,TRAPPC13,SATB1,FNDC3A,SEC31A,CCDC88A,LIMCH1,ERC1,ZC3H13,CLASP2,TROVE2,ZNF302,SYNE2,NUDT10,ANKRD12,MTCL1,CAMTA1,ATMIN,ZEB1,TRIM2,RPGRIP1L,SYNE1,OBSL1,SIK3,AP4E1,TMPO,R3HDM1,TPM1,ANKRD20A2,SGK3,USP1,ZNF709,BCL2L13,TBC1D15,ZNF711,MICU3,KCNT2,FSTL5,ZNF195,SLC30A4,PRDM10,MDH1B,SLC17A7,PARP11,PDSS2,MARCH8,PHTF2,FRMD6,GAN,SPATA13" MicroRNA hsa-miR-206:mirSVR_highEffct hsa-miR-206:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.08E-81 1.16E-77 1.71E-80 1.57E-79 209 1188 "RALGAPA1,CLK4,ABHD6,KDM5D,NDRG3,SLC24A4,HACE1,ALCAM,ARHGAP20,AMPD3,OGT,CCDC146,MAP4K3,UPRT,TMEM108,ZNF582,BMPR1B,SYNJ1,FUBP1,IL33,CA8,KALRN,SEPT7,L3MBTL4,MAGI1,UBE2L6,CLCN3,CLTC,C4orf33,CNN3,COL4A5,SLC4A8,AHCTF1,BAG4,SLC35F1,CREM,RNF14,C1QL2,CRYM,PDE4DIP,DZIP3,DCAF8,MATR3,KCTD8,DGKB,YTHDC1,JAKMIP2,ELMO1,TIAM2,PLPPR4,DLX1,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,MRO,KMT5B,TMEM35A,EPHB1,RABEPK,MRPL37,CDKL3,ADGRV1,CEP78,CHST15,FER,POLR1B,FGFR1,SEC23B,IP6K2,ANKFY1,NELFCD,AKAP3,NBEA,UFM1,CGREF1,ST6GALNAC3,FYB1,GABRA3,DENND2A,HIGD1B,ZNF559,LRRC37A6P,KIAA1841,ARFIP1,PCDH17,PPARGC1A,MALT1,FERMT2,WDFY3-AS2,ADGRA3,GPD2,MCHR1,ZNF496,RNF165,AP4S1,PSIP1,RASSF8,HMGCR,ZDHHC15,IDH3A,IGF1,FAM69A,INSM1,SLC35G1,METTL21A,KIF2A,STXBP5,KTN1,LAMP2,PAXBP1,MAP2,MEIS1,MYO9A,SLC11A2,NTRK3,ZNF713,GPR137C,PDCD2,ENPP2,NALCN,KCTD15,PURG,TRHDE,SCHIP1,MINDY2,PRKACB,MAPK3,GRAMD1C,HYDIN,TMEM260,ZIK1,PTPRG,MSANTD2,CRTAC1,SLC25A36,NUDT11,EXD2,C12orf49,CARF,ROBO2,RPL15,FBXW7,KCNIP3,ZNF568,AP1AR,SCP2,MRAS,TRA2B,SH3GL3,FNDC3A,ANKRD6,PEX26,SLC6A11,SLC8A1,ANKRD36,SNAP25,SNRPN,USP33,SP2,SAMSN1,LARP4,SS18,NXT2,STAU1,SYN2,TACR1,ALG1,TRIM2,CLASP1,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,LRRC8A,NPL,SYNPO2,TRIO,AMACR,TTC3,RPL7L1,FAM155A,UBE2H,TBC1D15,LMF1,WIPF1,ZFP37,STOX2,TMEM178A,HPS4,SLC17A7,WNK3,PARP11,PHTF2,ADAMTSL3,TIGD6,MSRB3,NETO2" MicroRNA hsa-miR-106a-5p:TargetScan hsa-miR-106a-5p TargetScan 2.29E-81 1.28E-77 1.87E-80 1.72E-79 189 969 "NCKAP5,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-17-5p:TargetScan hsa-miR-17-5p TargetScan 2.29E-81 1.28E-77 1.87E-80 1.72E-79 189 969 "NCKAP5,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-106b-5p:TargetScan hsa-miR-106b-5p TargetScan 2.29E-81 1.28E-77 1.87E-80 1.72E-79 189 969 "NCKAP5,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-1183:mirSVR_highEffct hsa-miR-1183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-81 1.31E-77 1.91E-80 1.76E-79 198 1066 "GALNT13,KIAA1211,PTCHD1,ADRB2,BEND6,ZNF608,RTL9,TXNDC16,HFM1,CDC42BPA,APC,UPRT,ZFYVE28,CADPS,ZBTB10,RNF182,BCHE,CFLAR,ARHGEF7,FUBP1,MTMR2,CA8,CAMK2A,VXN,KRIT1,LOC730101,TIGD7,CFL2,SRSF11,CHN2,CNOT8,RAB33A,HECTD1,CNN3,TBPL1,RTTN,CNRIP1,SLC35F1,SEC31B,CREM,RNF14,NCOR1,CS,MROH8,CSF1R,ERC2,KCTD8,DAPK1,MYEF2,TIAM2,GSDME,PLPPR4,FAM107B,USP3,CDON,ARRDC4,E2F6,EDIL3,SEZ6L2,WDPCP,EDN3,RASGRP1,SEMA3D,KLHL5,FSD1L,SUGP2,RGS17,TMEM35A,CALCRL,DCTN4,TUBD1,EPB41L2,CEP85L,F8,SCML2,ST3GAL6,SPSB4,SUCO,ATP5PD,SMC2,ATP2C1,ERGIC3,ST6GALNAC3,FYB1,ERAP1,SULT1C4,MSTN,ARFIP1,PCDH17,GGT7,GHR,PPARGC1A,RAB40B,FERMT2,PCLO,GRIA2,PSIP1,RASSF8,VSIG4,ZNF491,NEGR1,NKD1,IL6ST,INPP5B,LRRTM1,STXBP5,NCOA7,SMAD1,SMAD9,MARK1,MAT2A,MBP,LRP1B,POC1B,ZNF680,MSI1,MYO9A,RTL5,TCEAL5,NEK1,NF1,VWA2,SLC11A2,NTRK2,NUCB2,OPA1,CNTN3,PDE4B,GPR85,CYTL1,NALCN,PIK3C2A,KCTD15,MTRF1L,FA2H,PPM1B,LRRN3,PRKACB,EPDR1,MAPK9,DIRAS2,MASP1,PTCH1,PTPRD,STRC,PPP2R3C,RAP1GDS1,ERI2,RNASE1,CCDC82,CARF,RORB,YY1AP1,CCDC102B,RPE,RPL15,ARMH4,ATXN2,LRFN5,TRA2B,SH3BGR,FERMT1,WDR47,SEPHS1,ATF7IP,MBD5,TMCC1,PDZD2,ITPRID2,NKAIN2,SULF2,VPS13A,SYT1,MGRN1,TCF4,DMXL2,ZFP90,ZEB1,TEK,ACTR6,BHLHB9,AMACR,STXBP4,TRPS1,UBE3A,OSBP2,RBFOX3,ZFP37,KCNT2,CADM2,HPS4,FZD3,DOCK8,HNRNPA3,RNF170,NHSL1,FXR1,NETO1" MicroRNA hsa-miR-3130-5p:mirSVR_lowEffct hsa-miR-3130-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.52E-81 1.41E-77 2.05E-80 1.89E-79 213 1235 "GALNT16,SLC24A4,KCTD16,OSBPL6,ARHGAP20,FAM135A,DPP10,APC,EPB41L5,TNRC6C,TMEFF1,NUMB,ATP1B3,ATP2A2,SLC2A11,SEC11C,SYNJ1,CACNA1G,KALRN,CAST,METTL6,CERS5,USP6,MTMR7,CBFA2T2,LRRFIP1,DIS3L,CHN1,TPP1,ARHGEF6,IQCK,WHRN,CNRIP1,PLCXD3,GREB1,CCDC144A,HDAC9,KATNAL2,ARMCX4,MYEF2,TIAM2,GSDME,GUCD1,GRIN3A,DYNC1I1,SLC25A18,ACOT8,MAMLD1,E2F5,ANKRD46,HEYL,SEMA3D,FRY,KMT5B,RASA4,EPB41,RCAN2,GPHN,VPS26C,ANKMY1,CLVS1,DLC1,SUCO,MEX3B,IP6K2,AGAP2,TPK1,NSG1,DOT1L,ABLIM2,GABRG1,RAPGEF6,ZNF274,ALDH1L1,USP19,GGTA1P,MALT1,TXNL4A,TCERG1,DBF4,GLYR1,MSL3,WDFY3-AS2,PRUNE2,FUT10,MCHR1,ATP2B1-AS1,PLCD4,LINGO1,FAM107A,FRMD5,FRMD3,TNFAIP8L3,GABARAPL2,HSF2,EID2B,IDH3B,ZNF181,C2orf72,METTL21A,GPR62,SYTL4,NCOA7,AQP11,CHST6,ADAM11,MEIS1,KITLG,AFF1,SAMD5,LYRM9,MYO7A,HNRNPM,SFR1,NELL2,NME4,NTRK3,OGG1,OPA1,PCSK5,PDE4D,OLA1,NLGN3,ZNF655,NLE1,TRHDE,ING3,SH3KBP1,PRKAB2,WBP1L,PIGG,BDNF-AS,PTPRB,PTPRE,USP47,ZNF793,RASGRF1,ZDHHC14,RGS12,SLC25A36,PBRM1,CARF,CYB561D1,RPL15,ZNF354C,DGLUCY,SCN8A,TNFRSF19,HSPA4L,FBXO11,ST6GAL1,PEX26,KANSL3,PKNOX2,KIF13A,SNRPN,FAM126B,FAM219A,PDZD2,KDM4C,ZBTB43,ZNF302,ZC4H2,RGL1,NSFL1C,VPS13A,ANKRD28,EXOC7,FBXW11,TPCN2,RPGRIP1L,CLASP1,SYNE1,DOCK9,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,FAM200B,AP4E1,CDH22,TLR4,RASD2,IL34,SMUG1,TSC1,ZKSCAN5,TUBB1,RPRM,FAM155A,UBE3A,USP1,VLDLR,WIPF1,ZIC2,ZNF28,ZNF70,SPIRE1,DHX33,SLC38A1,PRDM10,URM1,PPP1R3F,KCNAB1,UBE3B,ADAMTSL3,SENP7,JPH3" MicroRNA hsa-miR-411:mirSVR_lowEffct hsa-miR-411:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-81 1.47E-77 2.14E-80 1.97E-79 216 1270 "ASPHD1,NDRG3,AXIN2,PTCHD1,OSBPL1A,CC2D2A,SRPX,BBOX1,FAM135A,APBA2,APC,EPB41L5,PPFIA3,PLA2G4C,NUMB,TMEM108,RNF182,ADGRB3,BBS2,DST,BTK,CACNA1G,C5,MYRF,IL33,CA8,CACNB4,CALB1,CAMK2G,SPAG9,METTL6,DGKI,LRBA,MAGI1,CDO1,NOG,SRSF11,ABCG2,MAP4K4,AKAP5,ABI3BP,CNRIP1,CREM,SNCAIP,PHF14,HDAC9,ZNF337,TMEM170A,AIF1L,YTHDC1,ZC3H11A,RHOBTB1,PLPPR4,SV2B,DMD,RPS6KL1,ACOT8,DTNB,ECM2,DNM1L,GOLT1B,WDPCP,YAF2,PHF20L1,GOLGA7,CALCRL,VPS13B,EPB41L2,RCAN2,LRRC17,GPHN,ETV1,EYA1,MRVI1,SCML2,FCGR1A,CEP78,FER,POLK,SEMA4D,FLT1,SYT3,FAM49B,ERGIC3,KHDRBS3,MPP6,CHL1,TRAF3IP2,GALC,RAPGEF6,MTHFD2,KIAA1841,GATM,SULT1C4,MAP7D2,LUZP2,FERMT2,ZNF496,KAT7,FAM222A,TNFAIP8L3,AGBL5,NEGR1,LRRC75A,NME9,JAK2,METTL21A,KIF2A,KIF5A,LINC00634,CYP27C1,KTN1,L1CAM,STMN1,MAN2A2,MAP4,MARK1,MATN2,MATN3,MBNL1,SAMD5,MYO7A,MYO9A,DNHD1,SMIM11A,SETD4,CNTN3,PAX6,ZNF655,PKD1,PCDH18,SMIM7,PURG,PDZRN4,TRHDE,LRP12,PSAT1,MAGEL2,MAPK9,HYDIN,RELN,CNTLN,MTMR10,PTN,PTPN13,PTPRE,PTPRG,PTPRH,PTX3,ZNF793,FAT4,RIC8B,PBRM1,ROBO2,ZC3H14,KIAA0895L,LRRK2,HSD11B1L,ATAT1,CLIP1,FAM192A,SH3GL3,FRMPD1,MYO18A,SYBU,SLC12A4,BTBD7,CPEB4,ZKSCAN3,MAST1,ANKRD36,MBD5,TMCC1,PDZD2,SOX11,ZC3H13,RBM26,CLASP2,ZC4H2,SS18,SEPT3,VPS13A,KIAA0930,CUX2,PCDHB15,PCDHB10,PCDHB3,SIRT1,ZFPM2,AP4E1,TIAM1,STXBP4,TRPS1,RUSC1,TTTY15,RPL7L1,UGT8,PLEKHH2,VLDLR,LMF1,VSNL1,CLIP2,ZNF711,ZBTB38,FSTL5,ZNF184,DNALI1,PRDM8,RNF103,ADAMTS9,NAV3,PLSCR4,HNRNPA3,JMJD1C,TIGD6,CPNE4" MicroRNA hsa-miR-376c:mirSVR_highEffct hsa-miR-376c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.91E-81 1.63E-77 2.37E-80 2.18E-79 230 1437 "RALGAPA1,ABR,GALNT13,PWWP2A,KIAA1211,PCDH19,TBC1D14,ALCAM,FAM135A,ALK,GPRASP2,OGT,ANK2,MAP4K3,PARG,APLP1,NCOA1,N4BP2L1,ATP6V0A1,DOCK11,SEC11C,SYNJ1,CACNA1G,CA8,CACNA2D1,CALB1,CALB2,KALRN,PTBP2,SLC25A14,VXN,CH25H,SPAG9,CBLN1,CBS,CD86,DGKI,ARHGAP33,LOC730101,CCPG1,RCBTB2,SOCS6,CHN2,NDST3,QKI,MAP4K4,AKAP7,FAM149A,COL9A1,LETMD1,SLC4A8,RCHY1,RTTN,FAM171B,CLOCK,CREM,CSF2RA,SOCS5,ERC2,CTH,DOCK4,HDAC9,KIF26A,PABPC5,HEPH,MFAP3L,ZC3H11A,GSDME,DDX46,SACS,SPOCK3,DLX1,USP3,CPEB2,DTNA,MAMLD1,EDN1,ANKRD46,FRY,FAM13A,PHF20L1,EGR3,PCOLCE2,C3orf18,EIF1,DENND4A,SIRPB1,FAM198B,TMEM132C,DLC1,FGF14,PSD2,C2orf88,NSG1,STAU2,MEGF10,GABRG2,ZNF274,SULT1C4,ARFIP1,COPS8,SPIN1,GPR75,MSL3,CBX1,GPD2,TDRKH,PCLO,GRIA2,SOX21,PSIP1,ATXN2L,MIER3,HNMT,ICA1,IRF8,MSL1,ZNF546,NKD1,FAM69A,INSM1,KCNJ16,SFXN5,SYTL4,NCOA7,CHIC1,TM6SF1,MEIS2,ZNF680,SAMD5,BLOC1S2,MSR1,ZNF92,LYRM9,NEFH,NRCAM,PCSK5,GNG2,PFKFB2,NALCN,PURG,TRHDE,ING3,EPB41L4B,MINDY2,PPP3CA,GRAMD1C,QRICH1,TMEM260,C1orf109,PEX2,PPP2R3C,TMEM255A,USP47,ZNF493,MSANTD2,ERI2,MORC4,RFX3,NUDT11,ROBO1,RORB,MEG3,CCDC112,RMI1,SATB1,ATXN7,CPEB3,CHD9,FNDC3A,DZIP1,DHX30,PKNOX2,SLC8A1,KBTBD4,BTBD7,CPEB4,RCOR3,LIMCH1,MBD5,LMBRD1,BDP1,SPP1,KDM4C,ZNF423,CLSTN2,LARP4,ERBIN,ZSCAN29,TTBK2,DIP2A,KANK1,SYNE2,SYT1,COBL,ANKRD28,DNMBP,ADGRL3,SATB2,PCDHB10,TEK,FAM200B,DICER1,TIAM1,BHLHB9,NR2E1,RIMBP2,SGK3,VLDLR,P2RY12,XPO1,ZBTB14,ZNF711,ZNF708,TCEAL7,CELF4,EVI5,RNF103,PLSCR4,FAM13C,AMN1,DOCK8,KAT6A,PHTF2,JMJD1C,RNF170,MSRB3,KLHDC1,NETO1,ZNF30" MicroRNA hsa-miR-3156:mirSVR_highEffct hsa-miR-3156:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.14E-81 1.76E-77 2.55E-80 2.35E-79 220 1318 "KCNH8,ACADM,CLK4,KDM5D,NDRG3,KIAA1211,PTCHD1,KIAA1324,ALCAM,ABCD2,ARHGAP20,FAM135A,AMPD3,CDC42BPA,LCORL,ZBTB10,TMEM108,DPY19L3,ADAM23,ADGRB3,BMPR1B,DST,ST3GAL5,ARHGEF7,FUBP1,DDR1,KALRN,CAST,ZNF501,LRBA,LRRFIP1,L3MBTL4,LOC730101,MAGI1,NDST3,RAB28,PLAA,FBXO7,HECTD1,MAP4K4,CNN3,MYRIP,CREM,HAPLN1,RNF14,ANKRD44,OSBPL3,SUSD5,FAM169A,PHF14,RUBCN,CCDC144A,GAPVD1,RIPOR2,RASSF2,TBC1D5,MATR3,IST1,DGKB,PITPNC1,ZBTB24,DDX46,RHOBTB1,SACS,CHRDL1,DMTF1,ACOT8,DTNA,GOLT1B,EDNRA,FAM13A,PHF20L1,KCTD3,C8orf37,EXTL2,NRN1,ARMCX1,SH3YL1,CEP78,FCGR3A,ZNF589,SEC24B,OLFM1,FGF13,TMEM164,POLK,RGPD5,EFCAB2,ATP2C1,CELF1,NSG1,ZNF44,DISC1,KIAA1841,SESN1,ADAM28,GGTA1P,PPARGC1A,MALT1,RUNDC3A,BRD8,HPGDS,SPIN1,CBX1,KCNMB4,GNAL,DIDO1,ADAMTS13,GRM8,ZBTB49,PSIP1,RASSF8,ATXN2L,ELOVL5,ZNF678,SLC35G1,KCND2,KCNJ16,LAMP2,NCOA7,GPR155,MATN3,MBNL1,MEIS1,MEIS2,COMMD5,ZNF92,MYO9A,NELL2,NTRK3,CHAMP1,GPR137C,GNG2,ABCB1,PIK3R1,XRN1,PDZRN4,MAPKAP1,ING3,EPB41L4B,CEP41,EPDR1,GRAMD1C,GDPD1,RELN,TMEM260,PTPN13,PTPRB,PPP2R3C,ZNF793,FAT4,ZNF493,MSANTD2,RFX3,PBRM1,CCDC82,EXD2,ROBO2,RPL15,STK32B,ABCA11P,ATXN7,SGK1,CPEB3,SHMT2,HKDC1,CHD9,BTBD3,ZNF430,CPEB4,LIMCH1,TMCC1,FAM126B,PDZRN3,DOK5,ZBTB43,CAMTA2,NKAIN2,ERBIN,NXT2,ELOVL4,DIP2A,STXBP1,TMEM150C,SYN2,COBL,ANKRD28,TACC1,TBL1X,KLHL4,TCEA1,TCF4,HIF3A,ITGB3BP,SLC44A1,LRRC8A,TMPO,FAM124A,ELP5,STXBP4,TTC3,UBE2H,SLC35A4,UGT8,PLEKHH2,BCL2L13,TBC1D15,ZNF711,ZNF142,EML6,UPF3A,CADM2,STOX2,WNK3,EPM2A,RGS7BP,RTN4,SMIM8,CASC15,TRAM2-AS1" MicroRNA hsa-miR-1244:mirSVR_lowEffct hsa-miR-1244:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.32E-81 1.86E-77 2.69E-80 2.48E-79 250 1687 "CLK4,ACTN1,KDM5D,CCDC85A,BRAP,RTL9,TBC1D14,NME5,WDR35,CC2D2A,SPARCL1,SPOP,ALCAM,UNC79,ARNTL,CADPS,MARK4,SLC4A4,BCL7A,NRP2,FUBP1,RAB29,LDLRAD4,CACNB4,KALRN,PTBP2,SPAG9,MTMR7,DCLK1,LARGE1,ZNF445,DLGAP2,CCPG1,LRWD1,RAB28,NRXN3,PPT2,MAP4K4,LY86,LETMD1,SLC4A8,ZFP28,CREM,RNF14,ANKRD44,OSBPL3,SIPA1L1,PHACTR3,CNTNAP2,SLITRK5,DZIP3,KIAA0040,PNPLA8,GAPVD1,SNPH,DCAF8,RASSF2,LIN54,MAML1,ARMCX4,ZNF804A,MFAP3L,KLHL3,RHOBTB1,GRIN3A,DNAH9,NR1D2,DRP2,DTNA,ECM2,ABCC5,EDN1,CNNM1,PHF20L1,SUGP2,KMT5B,AASS,IRAK4,DCTN4,LRRC17,SRRM1,ERBB4,IGSF6,ETV1,PIPOX,FKTN,MED12L,OLFM1,SYNCRIP,ATP13A4,EFCAB2,TMEM107,PDLIM5,ZNF605,HHIPL1,GABRA3,ACSS1,GCNT2,TUBGCP4,GDF9,TCERG1,TOX3,MSL3,PRUNE2,TPPP,ZBTB49,AP4S1,ADAMTS6,FRMD3,HLF,GABARAPL2,AGFG1,TJAP1,IL6R,JAK2,KIF2A,KTN1,LMO2,GPR155,MAN2A2,MAP2,MAP4,TM6SF1,KCTD6,PPM1L,AFF1,MMP16,MSR1,MXI1,LAYN,DNHD1,SETD4,IGSF11,P2RX7,GPR137C,PDE4B,PFKFB3,OLA1,PIK3R1,ZFYVE21,GPSM2,NLE1,ZNF426,MAPKAP1,SCHIP1,RETREG2,SEPT4,FA2H,PPM1B,RANBP3L,RASGEF1B,PRKACB,HYDIN,BCAS3,PIGG,NCR3LG1,PTPRD,PTPRO,TUG1,MARCH1,CEP97,RAP1GDS1,RBBP6,MSANTD2,RGS3,PRIMA1,RIC8B,RNASEL,LGI2,ROBO1,RORB,ZC3H14,GLDN,PTGR2,KCNIP3,FAM192A,SATB1,SCN8A,KIF27,RASA3,SCAF8,FERMT1,CPEB3,SHC4,CNKSR2,NLGN1,SLA,SLC2A5,ARHGEF40,SLC14A1,ATF7IP,SMARCC2,CDK5RAP2,LIMCH1,SNCA,MBD5,TMCC1,DOP1A,BDP1,MYCBP2,RBM26,LMO3,SSTR1,ZC4H2,ADHFE1,SEPT3,ANKRD28,TACR1,MTCL1,TCF4,SIN3B,DMXL2,ZFP90,ZEB1,TRIM2,TCF12,SYNE1,DOCK9,GPRIN3,C18orf54,AP4E1,AKTIP,SLC44A1,TTTY15,SGK3,TUBB1,ZNF610,FLRT2,MTCH1,RICTOR,GUSBP1,XPO1,CFAP298,ZNF24,MKRN3,ZBTB38,ANKS1B,SMARCAD1,DHX33,SLC38A1,KCNAB1,RGS7BP,DNAH10,FAM13C,MRPL47,PHTF2,ADAMTSL3,JMJD1C,TTC7A,SOCS4" MicroRNA hsa-miR-325-3p:TargetScan hsa-miR-325-3p TargetScan 4.02E-81 2.25E-77 3.26E-80 3.00E-79 253 1727 "ACADM,ACHE,NCKAP5,NDRG2,ELFN2,ADCY6,PLEKHH1,PWWP2A,KIAA1211,RNF150,ESYT2,MTA3,KLHL13,CASKIN1,AK2,ABCD2,GPRASP2,DOC2A,AMH,AMPD3,CDC42BPA,PPFIA4,APLP1,APOC1,APOC2,AQP6,PLA2G4C,CADPS,MARK4,RASL11B,INSYN2B,ATP2B2,ATP6V1G2,DOCK11,BACH1,HCN2,BCS1L,BMP7,FUBP1,LDLRAD4,CALM1,PTBP2,CAMK2A,HIP1R,CCNT1,CBFA2T2,CDC25B,CLGN,NUMBL,CFL2,CHN1,B4GALT6,NRXN3,CCDC151,IGLON5,COL9A1,LETMD1,AHCTF1,NRG2,CDC42BPB,ENTPD4,CLIP3,CNTNAP2,PPP6R2,DCAF4,GPRASP1,DCAF8,MATR3,MAML1,DGKG,SCRN1,DBN1,ARMCX4,ARMCX2,JAKMIP2,GUCD1,MTX3,DMD,DOCK2,RCAN1,GOLT1B,EDNRB,ANKRD46,HEYL,FAM13A,EIF4G2,CERCAM,ELN,EIF1,EMX2,EPB41,ERBB4,GMPR2,HSPA12B,REEP2,ARMCX1,CLVS1,FGFR1,MAD2L2,FOXF2,NOP56,FLYWCH1,C2orf88,AK8,CGREF1,FUT9,NEURL4,GABBR1,RAPGEF6,CPLX1,CYP46A1,MMADHC,GFRA2,CSDC2,COPS8,LUZP2,DCLK2,GNAO1,GNG4,GPD2,GPR12,GPER1,GPR37,GRIK4,PTPRT,COQ10A,GSTM5,KAT7,LINGO1,RASSF8,PACSIN2,AGBL5,HP,NEGR1,IDH3B,LRRC25,INPP1,C2CD4C,KCNB1,KCND1,KCNF1,KCNJ5,KLHL23,KCNN3,IPO5,KTN1,LIFR,PAXBP1,HECTD2,NCOA7,ASPRV1,GPR155,MBNL1,MEF2C,POC1B,MMP16,MN1,SAMD5,ADAM22,SAMD14,LAYN,P2RY13,NEFM,ALDH1L2,NFIX,NFYA,NOVA1,PCBP3,NUCB2,IGSF11,CHAMP1,CLDN11,P2RY1,PCSK1,PDE1B,PFKFB3,OLA1,PIK3R1,PKM,FAM216A,PLEC,FXYD1,PNMA3,PPP2R2C,PPP3CA,PRODH,NDUFS7,BCAS3,ANKHD1,ENOX1,RASGRF1,KHDRBS2,RDX,PRRT2,RFX3,PRIMA1,KLHL11,RNASE1,RIC8B,RNASEL,PCMTD2,BAALC,EMID1,HUNK,KCNIP1,SATB1,ATXN7,SCN2B,FNIP1,FBXO11,FAM81A,ELMO2,GKAP1,ABTB1,CDK5RAP2,MAPKBP1,MYO16,HECW1,MYCBP2,PEG10,ARHGAP26,DDN,NFASC,POGZ,ELOVL4,PHLDB1,ARHGEF9,ANKRD28,ANKRD12,FAM208A,SATB2,NAT16,CDH22,RELL2,BHLHB9,FAM124A,RIMBP2,RUSC1,CLIP2,KCNK12,LGI4,INTS3,AMN1,FZD3,MRPL47,MARCH8,RTN4,HNRNPA3,FBXO36,RNF170,ADAMTS10,FRMD6,PRRT4" MicroRNA hsa-miR-1284:mirSVR_highEffct hsa-miR-1284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.60E-81 2.57E-77 3.72E-80 3.43E-79 206 1159 "KCNH8,ACADM,NDRG3,FMNL2,AXIN2,PTCHD1,ADRB2,KCTD16,HACE1,HFM1,FAM135A,LRCH2,SEMA7A,SMIM29,TMEFF1,ZFYVE28,RASL11B,DYNLL1,ATP2A2,ATP2B2,ALDH7A1,CARMIL3,ADGRB3,CFLAR,NAE1,SCAPER,JAZF1,LDLRAD4,CABP7,KALRN,SPAG9,CERS5,DIS3L,SRSF11,PLEKHB1,NDST3,RAB33A,CLCN3,C4orf33,QKI,HECTD1,SLC4A8,ZFP28,CREM,ANKRD44,SIPA1L1,VCAN,PDE4DIP,CYBB,BOC,TIAM2,ZC3H11A,SPOCK3,WDR20,CPEB2,MAMLD1,DNAJB6,E2F5,AASDH,YAF2,PHF20L1,KMT5B,VPS13B,EPB41L2,GPHN,STX2,DENND4A,NCALD,ADGRV1,TAOK3,FKTN,KAT8,SYNCRIP,UFM1,ST6GALNAC3,GABRG2,GAD1,ERAP1,MTHFD2,ZNF559,ADAM28,MMADHC,PCDH17,GHR,ZNF638,RAB40B,GNAO1,FAM19A2,KAT7,ZBTB49,RASSF8,MIER3,ZDHHC15,HSF2,LRRCC1,ZNF678,ITPKB,JAK2,KCNQ3,KIT,STMN1,PACRG,PIK3AP1,MAP2,MAP6,MARK1,MARK3,MEF2C,SRSF12,MEST,MKLN1,ADAM22,MSR1,MYCN,MYO9A,ZC3H12B,NDP,CNOT4,SLC11A2,NRCAM,NTRK3,CHAMP1,GPR137C,DPY19L2P2,PCDH8,PDE1C,PDE4B,GNG2,PIK3C2A,ZNF655,GPSM2,PRIMPOL,STRN3,SCHIP1,ING3,EPB41L4B,PPM1B,PPP2R2C,HYDIN,APTX,SNRK,PTCH1,PTN,TMEM260,QDPR,FAM184A,ENOX1,OXR1,KHDRBS2,MSANTD2,REV3L,RNASEL,SETD5,CARF,GSTCD,ROBO2,KIAA0895L,PTGR2,NCBP3,TRAPPC13,SCAF8,KIF21A,FNDC3A,DHX30,ZNF334,CXXC4,KIF13A,SNRPN,USP33,DOP1A,TRERF1,SPART,ERBIN,ZSCAN29,VPS13A,TACC1,CAMTA1,FAM208A,TRIM2,PCDHB4,ZFPM2,AKTIP,HEY1,RGMB,SYNPO2,ANKRD20A2,EIF4ENIF1,UBE3A,PLEKHH2,VLDLR,WIPF1,ZNF781,ZIC2,ZNF711,ZNF17,SMARCAD1,STOX2,NAV3,DOCK8,RTN4,PHTF2,RNF170,SNX14,FRMD6,GAN,SENP7" MicroRNA hsa-miR-1179:mirSVR_highEffct hsa-miR-1179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-81 2.95E-77 4.26E-80 3.92E-79 202 1115 "CCDC85A,ZNF608,PCDH19,WDR35,HFM1,SPARCL1,ALCAM,GPRASP2,ZFAT,OGT,DPP10,LRCH2,TNRC6C,SEMA4G,ARNTL,ADAM23,ADGRB3,BBS2,RGS9,ZNF599,CFLAR,SCAPER,WASF1,CACNA2D1,THSD7A,PRC1,CD38,LRBA,MAGI1,CHGB,B4GALT6,SLIT2,CPNE6,NRXN3,CLTC,ZFP28,FAM171B,RBM39,ANKRD44,CS,SNCAIP,VCAN,DZIP3,UBXN2A,ARHGAP24,DBI,MYEF2,GSDME,PLPPR4,WDR20,DOCK2,ECM2,DNAJB6,DNM1L,E2F5,CELSR3,FAM13A,CALCRL,TUBD1,LRRC17,CEP85L,RRAGB,NSRP1,SCML2,GORAB,FGF11,FGFR1,POLK,KHDRBS3,STAU2,MSANTD4,SARAF,OGA,HRASLS5,GABRG2,TRAF3IP2,GALC,ZNF559,GATM,GHR,PPARGC1A,GLI2,RAB30,TOX3,GNAO1,FERMT2,ADGRA3,PRUNE2,ATP2B1-AS1,FAM19A2,IRAK3,INSYN1,MIER3,USP51,SMAP1,IRF8,FAM95B1,SOWAHA,SCIN,IL12A,KCNJ16,CYP27C1,PAXBP1,LMO2,HECTD2,NCOA7,PACRG,MEIS1,BLOC1S2,DNHD1,SLC11A2,LOC100128398,GPR137C,GLIPR1L2,PCDH9,PDE4D,PIK3C2A,FAM218A,PCDH18,SEPT4,MBOAT7,DRAM2,PPM1B,PRKCB,EPDR1,RELN,VPS13C,SNRK,PTCH1,SPDL1,PTPRB,PTPRO,C1orf109,PPP2R3C,MARCH1,PID1,USP47,GTDC1,RGS3,RGS4,CCDC82,CARF,RPE,RPL15,PTGR2,ZNF568,ATXN2,ZFP2,KIF21A,FERMT1,CNKSR2,ZNF430,SEPHS1,SLC8A1,ARHGEF40,BTBD7,RCOR3,SNAP25,MBD5,SNRPN,PDZD2,BDP1,CLASP2,NKAIN2,VPS13A,TACR1,PJA1,CAMTA1,ZEB1,RPGRIP1L,CLASP1,SYNE1,PCDHB9,PCDHB4,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,SLC44A1,TLR4,NR2E1,RUNDC3B,RPL7L1,CCDC14,WIPF1,MICU3,KCNT2,TRIM9,ZNF45,SPIRE1,TUBA1A,PPP1R3F,WNK3,PDSS2,EPM2A,UBE3B,FRMD6" MicroRNA hsa-miR-450b-3p:mirSVR_lowEffct hsa-miR-450b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.82E-81 3.26E-77 4.69E-80 4.32E-79 221 1334 "ABCF1,EMILIN3,NCKAP5,GALNT13,ADORA1,HECW2,OSBPL1A,AMPD2,ZFAT,CDC42BPA,EP400,APLP1,TNRC6C,PCDHGB4,ZBTB10,TMEM108,SLC4A4,KSR1,ARHGEF7,CASTOR3,KALRN,SPAG9,ZNF501,USP6,MAGI1,CDO1,NRXN3,HECTD1,CNN3,ABI3BP,TOGARAM2,SLC35F1,CLOCK,CREM,RBM39,CLIP3,CSF2RA,PLXNA4,DCAF4,CCDC144A,BOC,RIPOR2,CENPL,LIN54,IST1,DNAL1,MYEF2,RHOBTB1,SV2B,KIF19,CHRDL1,DYNC1I1,MAMLD1,ABCC5,WDPCP,EDNRB,CELSR3,FAM13A,AASS,CERCAM,SPEG,RASL12,PTK2B,FGF1,PRKAG2,HPCAL4,SYNCRIP,ANKFY1,NOP56,CELF1,ABLIM2,FYB1,MEGF11,GABRB3,GHDC,DISC1,ZNF638,LNX1,WDFY3-AS2,FUT10,LILRA2,STON1,GRM2,GSTM5,ATOH8,PACSIN2,DHX35,FAM95B1,SOWAHA,ITGAM,SLC35G1,KCNB1,KIF2A,STMN1,PAXBP1,SYTL4,SMAD1,GPR155,MATN3,MEF2C,MID1,PPM1L,MITF,MPP2,ADAM22,ZNF92,ZNF862,VWA2,DPY19L2P2,PCDHGC3,CDK18,PDE4D,GNG2,ZNF655,PKM,NLE1,SLC25A23,PLXNB1,MAPKAP1,LRP12,PPARA,PRKAB2,CNNM2,BCAS3,PTK2,ZIK1,PTPRH,PEX2,TUG1,TMEM231,KHDRBS2,RDX,CRTAC1,TRIM68,GTDC1,KLHL11,SETD5,NEK11,ZC3H14,GLDN,MEG3,HUNK,ATAT1,SEMA6D,ATXN7,SCP2,TNFRSF19,R3HDM2,NLGN1,KDM4D,SLC8A1,KBTBD4,SLC12A4,BTBD7,ATF7IP,ZFP1,ANKRD36,MBD5,USP33,DOP1A,ZSWIM8,SP4,HECW1,PEG10,RBM26,LARP4,STAU1,SULF2,SEPT3,NSFL1C,JMJD6,TACC1,PJA1,CAMTA1,SIN3B,KIAA0930,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,FAM189A1,TEK,DICER1,ENHO,FAM124A,PIK3R5,CDK20,RGMB,METTL3,ELP5,STXBP4,GORASP1,BCL2L13,CCDC14,TBC1D15,XPO1,ZNF711,ZNF540,POLR3H,DPYSL5,DHX33,EMSY,GDPD5,LINC02210,HPS4,PLSCR4,DNAH10,DOCK8,UBE3B,HNRNPA3,TRAM2-AS1,NETO2,NETO1" MicroRNA hsa-miR-618:mirSVR_highEffct hsa-miR-618:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-81 3.63E-77 5.23E-80 4.81E-79 199 1083 "KDM5D,NDRG3,AXIN2,SLC24A4,INTS2,AK2,ADGRF5,FAM135A,DPP10,LCORL,PKP4,TNRC6C,USP37,PPP4R4,ZBTB10,SLC4A4,SEC11C,KSR1,DST,JAZF1,GPC2,ISPD,SPAG9,ZNF501,METTL6,USP6,DGKI,MAGI1,NOG,SRSF11,CLTC,CNGA3,IGLON5,CNN3,ARMC8,LETMD1,TOGARAM2,ZFP28,ANKRD44,NCOR1,SIPA1L1,CNTNAP2,HDAC9,HDAC4,TMEM170A,SPOCK2,YTHDC1,MYEF2,ALKBH8,PLPPR4,CHRDL1,DMD,NR1D2,PDCD6IP,ECM2,MAMLD1,FRY,TENM1,EMX2,EPB41,SRRM1,TLR7,FAM198B,TMEM132C,DLC1,CEP78,GORAB,SEC24B,SLC9B2,FER,FGF13,FGFR3,BAIAP2,SEMA4D,ATP6V1H,ABLIM2,FYB1,ZNF44,GABRG2,BRD8,LPAR4,GRB10,FAM19A2,HNF4G,NEGR1,SMAP1,EID2B,IRF8,ZNF181,KIT,HECTD2,MAP2,MAP4,MARK1,EFHB,MEIS1,SRSF12,AFDN,LAYN,MYO6,NEXMIF,NEK1,NF1,NOVA1,NTRK2,NUCB2,IGSF11,CHAMP1,GPR137C,PAX6,GPR85,GNG2,CYTL1,FAM218A,CCSER2,PLCL1,LRP12,ING3,EPB41L4B,HYDIN,DCHS2,NWD1,RAP1GDS1,OXR1,FIGN,RGS4,KLHL11,RIC8B,NUDT11,ZNF532,CARF,ROBO1,RORB,SPIN3,ZC3H14,MCMBP,ATP8B4,KCNIP1,CCDC112,SALL1,SCN8A,SH3GL3,CPEB3,FBXO11,FNDC3A,FHOD3,NUBPL,PPP4R3A,BTBD3,CCDC88A,CPEB4,SMARCD3,MBD5,PDZRN3,USP33,SP4,KDM4C,ZNF423,ZNF302,NXT2,SYT1,AGTPBP1,DMXL2,SATB2,TRIM2,PCDHGB7,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TMEM9,TPM1,DCBLD1,UBE3A,TOM1L2,CCDC14,TBC1D15,WIPF1,ZFP37,ZNF711,ZNF45,LYPD6,CELF4,ZNF195,SLC30A4,MDH1B,PLSCR4,RTN4,FBXO36,SNX14,KLHDC1,RNF146,SOCS4,GAN" MicroRNA hsa-miR-135a*:mirSVR_lowEffct hsa-miR-135a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.05E-81 4.51E-77 6.47E-80 5.96E-79 210 1208 "NCKAP5,KLHL32,TMCC3,GALNT13,ADD2,ADRA1D,OLMALINC,SLC24A4,PCDH19,ADGRF5,MARCH4,PDZD4,APLP1,BCAS1,SLC2A11,MYOM1,TTLL9,BBS2,MPDZ,CACNA1G,WASF1,CA8,CALB1,CALM1,HAP1,VXN,ISPD,CBR1,CBS,CD38,SEPT7,ASIC3,TPP1,QKI,ARHGEF6,AKAP7,COL4A5,COL11A2,ABI3BP,RBM39,CLIP3,TRIM69,RGS6,OSBPL3,IPCEF1,SOCS5,PDE4DIP,CST3,HDAC9,SNPH,DCAF8,ZNF337,TBC1D5,DGKG,SCRN1,ZNF804A,HEPH,FBXL5,DDX46,SNAP91,GRIN3A,RAB39B,DMTF1,DTNA,SEZ6L2,EDN1,EDNRA,CNNM1,KLHL5,FSD1L,VPS13B,EPB41,EPB41L2,RCAN2,RRAGB,SIRPB1,EYA1,CD320,MRVI1,FAM198B,FGF12,RGPD5,FAM49B,ZNF605,ERGIC3,KHDRBS3,DLL3,ZMAT1,ZNF234,LRRC37A6P,NEU3,ALDH1L1,TUBGCP4,POLL,KCNMB4,GNG4,CCDC184,TMEM121B,RNF165,ZBTB45,SOX21,ADAMTS6,GUCY1B1,IRAK3,HAS2,ZDHHC15,SMAP1,KCNN2,KIT,STXBP5,LAMP2,LIFR,GPR155,MAP2,MAP6,MAT2A,TM6SF1,KCTD6,ZNF680,MYO6,MYO9A,CNOT4,NRCAM,SETD4,OGG1,FAM225B,P2RX7,PDPK1,ZNF655,ZFYVE21,MTRF1L,PSAT1,ING3,SH3KBP1,WBP1L,CNTLN,PTCH1,ELOVL2,ZIK1,PTPRB,MARCH1,ROGDI,MSANTD2,TRIM68,LGI2,SUGCT,CARF,SNX22,SPIN3,ATP8B4,SGSM1,ADAL,STK32B,LRRK2,AP1AR,MAPK12,SARS,SCP2,KIF16B,ASAP3,FBXO11,FNDC3A,ANKRD6,RCOR3,MBD5,SNRPN,PDZRN3,SP4,NMNAT2,TSPYL2,RBM26,NFASC,DIP2A,ASTN2,TACR1,EXOC7,CLASP1,NSD1,FRYL,RNF216P1,TEK,FAM200B,SIRT1,AP4E1,AKTIP,TLR4,RIMBP2,CSMD1,STXBP4,UBE2H,VLDLR,LMF1,PCDH20,ZNF24,KCNT2,ZNF138,CELF4,POLR3H,EML6,ZXDA,PRTFDC1,DNALI1,STOX2,GAL3ST3,ITM2C,FAM47E,FAM13C,FZD3,DPF3,SOCS4" MicroRNA hsa-miR-337-3p:mirSVR_highEffct hsa-miR-337-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.66E-81 4.84E-77 6.95E-80 6.40E-79 202 1118 "ABHD6,ESYT2,HECW2,AK2,HFM1,ALCAM,ABCD2,PCDH10,FAM135A,CCDC146,ARMC12,PARG,EPB41L5,ZBTB10,N4BP2L1,SEC11C,BCHE,PROM1,SCAPER,WASF1,DDR1,CACNB4,LURAP1,THSD7A,PTBP2,VXN,SCARB1,QKI,CNTN1,AKAP6,AKAP5,ABI3BP,SLC35F1,C2CD2,RBM39,HAPLN1,CRY2,SNCAIP,PDE4DIP,PLXNA4,PUM1,ZSCAN23,BOC,LIN54,KIAA0586,MFAP3L,ALKBH8,CHRDL1,E2F5,AASDH,SNX29,EDNRA,SEMA3D,FSD1L,KMT5B,GOLGA7,TMEM35A,RABEPK,NRN1,RPS6KC1,PTK2B,SCML2,DLC1,FER,POLR1B,FGFR3,ANKFY1,PSD2,UFM1,ST6GALNAC3,MSANTD4,GALNT15,GAD1,ERAP1,ZNF559,DISC1,GDF9,MMADHC,GHR,PPARGC1A,GPR75,GNAO1,PCLO,BVES,PSIP1,GUCY1B1,HLF,MSL1,ZNF181,RBPJ,LRRCC1,JAK2,SLC35G1,KCND1,LIG4,MARK1,MBNL1,LRP1B,MEIS2,SRSF12,MEST,MID1,MMP16,ADAM22,NFE2L2,CNOT4,NPR2,NTRK3,NUCB2,CNTN3,PCDH9,RETREG1,PCDH18,ING3,EPB41L4B,PPM1B,PRKAB2,RASGEF1B,CEP41,HYDIN,DCHS2,VPS13C,PTCH1,SPDL1,PTPRN2,TTC13,ZNF615,PID1,CEP97,ZMAT4,MORC4,PBRM1,ZFHX4,TMLHE,CARF,GSTCD,CYB561D1,RORB,ARMH4,BAALC,GLDN,ZNF331,AP1AR,SCP2,ZFP30,KIF21A,SH3GL3,CPEB3,HKDC1,FHOD3,ANKRD6,SLA,EPN2,DHX30,FAM214B,ARHGEF40,CCDC88A,CXXC4,ZNF667,SNRPN,SP4,KDM4C,CDK19,RBM26,LMO3,POGZ,ZNF302,PRRC2C,VPS13A,SYT1,TACC1,ANKRD12,SYNE1,PCDHB15,FAM189A1,PCDHB9,GPRIN3,FAM124A,RIMBP2,TPM1,RUNDC3B,TTTY15,EIF4ENIF1,WIPF1,ZNF781,LGI4,PCDH20,ZNF142,ZNF154,SPIRE1,EMSY,FIP1L1,PDSS2,AMN1,DOCK8,HNRNPA3,CASC15,FXR1,FRMD6,NETO2,NETO1,CPNE4" MicroRNA hsa-miR-3074:mirSVR_highEffct hsa-miR-3074:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-80 5.95E-77 8.52E-80 7.85E-79 200 1097 "VWA5B2,RALGAPA1,ACHE,CLK4,AXIN2,PLEKHH1,ADORA1,PWWP2A,HACE1,ZFAT,SLC4A4,ALDH7A1,BARD1,SYNJ1,ARHGEF7,FUBP1,KALRN,CH25H,CBLN1,KRIT1,CCNH,MTMR7,CD38,CDH2,MAGI1,DLGAP1,CFL2,B4GALT6,RAB33A,PLAA,C4orf33,AKAP6,LETMD1,ABI3BP,RCHY1,RTTN,AKAP12,ANKRD44,NCOR1,CSF2RA,CST3,APPL1,CTH,CYBB,HDAC9,GAPVD1,ZNF804A,ALKBH8,RHOBTB1,RAB39B,CASP8AP2,ABCC5,EDIL3,EDNRB,ANKRD46,FAM13A,KMT5B,ASB3,PLEKHA1,CALCRL,DENND4A,ADGRV1,ABCA8,CEP78,GORAB,FER,SUCO,ANKFY1,SLC37A3,SMC2,SARAF,AP4B1,ZMAT1,MEGF11,FAM120B,RAPGEF6,ZNF274,PPARGC1A,RAB30,PRUNE2,TDRKH,LPAR4,GRB10,GRIA2,AP4S1,RABL2A,IRAK3,ZHX1,ARHGAP36,ELOVL5,HNMT,TCEAL6,DHX35,LRRTM1,NME9,KCNN2,KHK,MARK1,LYPLAL1,TM6SF1,LRP1B,MID1,MXI1,MYO9A,NEK1,NF1,NFE2L2,SLC11A2,ZNF713,CNTN3,PRTG,PDE4D,PIK3C2A,FAM218A,KCTD15,STRN3,PSAT1,POLR2F,PPP2R5E,PRKACB,PKIA,MAPK9,RELN,SAMD9,VPS13C,PTCH1,ANKHD1,TMEM260,PTPRE,FAT4,RBBP6,ERI2,KLHL11,CARF,CCDC102B,SPIN3,LRRK2,KCNIP1,TRAPPC13,RMI1,ATXN7,LRFN5,GALNT10,SUPT20H,PPM1E,CPEB3,CHD9,FHOD3,SEC31A,PKNOX2,SEPHS1,SLC8A1,NAPB,GLT8D1,ZNF423,RBM26,LMO3,ATP10B,CLASP2,NUDT10,PLCB1,PJA1,TAF9,TRIM2,RPGRIP1L,SYNE1,PCDHB6,FRYL,TEK,DICER1,SIRT1,ZFPM2,AP4E1,TIAM1,ASXL3,BHLHB9,TLR4,ERCC6L2,TNS1,NPL,WBP2,DCBLD1,EIF4ENIF1,UBE2H,PLEKHH2,MTCH1,WNT7A,CLDND1,XRCC4,ZNF711,ZNF138,PLSCR4,HRASLS,PHTF2,ACTR3B,JMJD1C,NETO1,DPF3,ST8SIA2,GAN" MicroRNA hsa-miR-20a-5p:TargetScan hsa-miR-20a-5p TargetScan 1.31E-80 7.32E-77 1.05E-79 9.62E-79 188 968 "NCKAP5,RNF150,PTCHD1,ADRA1B,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-93-5p:TargetScan hsa-miR-93-5p TargetScan 1.31E-80 7.32E-77 1.05E-79 9.62E-79 188 968 "NCKAP5,RNF150,PTCHD1,ADRA1B,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-20b-5p:TargetScan hsa-miR-20b-5p TargetScan 1.31E-80 7.32E-77 1.05E-79 9.62E-79 188 968 "NCKAP5,RNF150,PTCHD1,ADRA1B,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-936:mirSVR_highEffct hsa-miR-936:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-80 7.40E-77 1.06E-79 9.71E-79 204 1143 "KDM5D,NME5,TXNDC16,SPOP,FAM135A,PKP4,APC,ARNTL,STX16,ALDH7A1,ADAM23,RGS9,NRP2,CALB1,P2RX6,SCARB1,DGKI,ARHGEF2,ZMYM4,CDO1,LRWD1,NOG,CFL2,SRSF11,CLCN3,CNR1,AKAP6,MAGED1,IGDCC3,SEC31B,CREM,RBM39,ANKRD44,SUSD5,SOCS5,DOCK4,HDAC9,GPRASP1,TCAF1,CENPL,MAML1,TMEM170A,DAPK1,SPOCK2,PABPC5,YTHDC1,ZBTB24,HEPH,USP3,DOCK2,ECM2,MAMLD1,ABCC5,KRBA2,E2F5,AASDH,TSPAN5,ANKRD46,RASGRP1,FAM13A,PHF20L1,KMT5B,TMEM35A,CALCRL,TUBD1,VPS13B,CDKL3,ADGRV1,CLVS1,TAOK3,CEP78,FDFT1,FGF12,TMEM164,SYNCRIP,FLNC,FAM49B,ZNF605,MPP6,MEGF11,GABBR1,CHL1,GABRB3,MTHFD2,ZNF559,PCDH17,PPARGC1A,GLI2,ZNF638,FAM222A,ZHX1,KIF5A,KTN1,L1CAM,HECTD2,NCOA7,ZNF667-AS1,MAP6,MBNL1,AFDN,ZNF680,MSR1,P2RY13,NEK1,NELL2,NF1,SLC11A2,OGG1,GPR137C,CNTN3,GPR85,PFKFB2,XRN1,PLCB2,PLIN1,ZNF426,MTRF1L,PSAT1,RETREG2,PPM1B,PPP2R5E,PPP3CA,EPDR1,HYDIN,DIRAS2,MASP1,SAMD9,CNTLN,STK32A,ZIK1,PTPRE,PTPRH,PTPRN2,PTX3,MARCH1,TMEM255A,ACSS3,RAP1GDS1,OXR1,RASGRF1,RIC8B,NUDT11,ELP2,RPE,BAALC,KIAA0895L,MEG3,CLIP1,SCN7A,KIF27,TRA2B,HSPA4L,SCAF8,CPEB3,SHC4,NLGN1,ABLIM3,SLC2A5,CCDC88A,BTBD7,CPEB4,SNRPN,RBM34,DOP1A,BDP1,RBM26,LMO3,CLASP2,ZC4H2,NKAIN2,SS18,ERBIN,ELOVL4,RGL1,NECAB1,ARHGEF9,TRIM2,PCDHB15,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,AP4E1,THRA,DCBLD1,RUSC1,ZKSCAN5,RICTOR,NDRG4,ZNF142,ZNF184,ANKS1B,EMSY,EVI5,PRDM8,RTN4,ADAMTSL3,MSRB3,GAN" MicroRNA hsa-miR-629:mirSVR_lowEffct hsa-miR-629:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-80 7.46E-77 1.06E-79 9.77E-79 237 1534 "CLK4,ABHD6,C3orf14,AXIN2,FZD9,BEND6,INTS2,RTL9,OSBPL1A,CC2D2A,FAM135A,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,VAT1L,LGR5,CDK10,PPP4R4,NUMB,CCAR2,ATP1B3,ATP2A2,RNF182,ADGRB1,ADGRB3,BBS2,BCHE,NRP2,BTK,CASTOR3,SGCE,GPC2,WASF1,CFAP410,CA8,CACNA1B,KRIT1,CERS5,CCNH,SEPT7,KCNAB3,DLGAP1,TBRG4,RCBTB2,MS4A7,QKI,SULT4A1,MAP4K4,CNGA3,SLC35F1,CREM,ENTPD4,SH2B1,CS,IPCEF1,SLITRK5,GPSM1,ARHGAP32,ZFYVE16,TBC1D5,KIAA0586,BRINP1,AIF1L,ARMCX4,ELMSAN1,HEPH,FBXL5,SNAP91,SV2B,DMD,CDON,DMTF1,ELN,STARD3NL,EMX2,EPHB1,RABEPK,IGSF6,TLR7,MRVI1,TAOK3,CHST15,FKTN,STRADA,FGFR1,AMOTL2,SUCO,FLT1,SLC37A3,NOP56,FLYWCH1,NELFCD,EFCAB2,SPECC1,FAM49B,CSPG5,HHIPL1,CHL1,GABRG1,ERAP1,DISC1,PCDH17,TTBK1,TCERG1,KCNMB4,ZNF782,GPD1,FAM107A,ADAMTS6,ATOH8,HAS2,ZHX1,NCKAP1L,ELOVL5,DHX35,IGF1,DISP2,CDH20,KCNJ5,IPO5,KTN1,LIMS1,SMAD1,MARK1,MAT2A,TM6SF1,KITLG,POC1B,MMP16,ADAM22,MYO9A,NF1,VWA2,NPR2,OCRL,OPA1,GLIPR1L2,CNTN3,GNG2,NLGN3,XRN1,SLC25A23,PURG,LRP12,EXOSC10,NECAB2,SH3KBP1,PPP2R2B,EPDR1,CNNM2,SNRK,MTMR10,PTPRG,ZNF615,OXR1,KHDRBS2,MSANTD2,RDX,RFX3,PBRM1,ZFHX4,TMLHE,CARF,ROBO1,YY1AP1,LRRK2,HUNK,RTN1,FAM192A,SAFB,SEMA6D,LRFN5,SCN8A,SGK1,KIF16B,SHC4,CHD9,FBXO11,DZIP1,CCDC88A,SLC12A2,ATF7IP,SMARCA4,DMRTC1,LIMCH1,SNRPN,MYO16,TRERF1,ZSWIM8,CDK19,CLSTN2,ERBIN,NEK4,DIP2A,KLHL7,ZC3H4,VPS13A,ASTN2,KLHL4,KIAA0930,TRIM2,NAT16,OBSL1,SIK3,FAM200B,DNAH7,DICER1-AS1,ZFPM2,AKTIP,SLC44A1,TIAM1,TLR4,R3HDM1,CSMD1,RASD2,NPL,DOK6,RGMB,PDSS1,STXBP4,ZKSCAN5,HIRA,VLDLR,GUSBP1,ZNF45,ZNF189,ZNF195,CADM2,SLC38A1,PRDM10,ADAMTS9,FAM47E,FAM13C,RTN4,KAT6A,HNRNPA3,FBXO36" MicroRNA hsa-miR-4266:mirSVR_lowEffct hsa-miR-4266:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-80 8.05E-77 1.14E-79 1.05E-78 226 1400 "ACADM,ASIC1,C3orf14,GALNT16,ADCY6,KIAA1211,AP2A1,MTUS1,SPARCL1,CARNS1,PITPNM2,LRFN1,EP400,KCNAB2,PPFIA3,LGR5,CASK,PCDHGB4,SLC4A4,CARMIL3,MPDZ,CFLAR,FUBP1,CACNA1I,CAST,USP2,P2RX6,ARHGEF1,SYNGR3,CD38,LRBA,ARHGEF2,CPNE6,NRXN3,DGCR9,CNGA3,CNN3,PCYT1B,AKAP6,LETMD1,CNRIP1,SLC35F1,FAM171B,AKAP12,ABCG1,CS,SEC24C,PDE4DIP,ERC2,GREB1,PUM1,KIAA0408,ARHGAP32,ZNF337,LONRF1,LIN54,GIT2,ARMCX4,YTHDC1,GSDME,POM121,DMTF1,CASP8AP2,DPYSL2,DNAJB6,ABCC5,TMTC1,YAF2,CELSR3,MBNL2,RCAN2,CLVS1,TMEM132C,CHST15,FCGR3A,ZNF589,MED12L,AGAP3,FLT1,NELFCD,JKAMP,HVCN1,STAMBP,AP4B1,FYB1,DENND2A,FAM120B,RAPGEF6,GATM,IGSF5,NEU3,GGT7,LYVE1,TXNL4A,LNX1,GRIN2D,GRM2,PRDM5,CIT,GSTM5,GSTT2,SOX21,TNFAIP8L3,HNF4G,HSF2,MSL1,KIAA1755,KCNQ3,IPO5,STMN1,SYTL4,NCOA7,ASPRV1,GPR155,MAPT,CHIC1,TM6SF1,MEIS1,MKLN1,ZNF680,BLOC1S2,MYT1,P2RY13,NFE2L2,NTRK2,OCRL,OGG1,PCDHGC3,PFKFB3,CCSER2,PLCB2,PLXNB1,ING3,RETREG2,FA2H,POLR2F,PPM1B,LRRN3,PPP5C,VSTM2L,HYDIN,WBP1L,QRICH1,PIGG,BDNF-AS,TMEM260,PTPRB,EML5,ZSCAN2,IQSEC3,DPF2,RET,GTDC1,PRIMA1,ZFHX4,C12orf49,ALG9,CARF,SNX22,ARMH4,FBXW7,BAALC,MEG3,NCBP3,SEMA6D,ATXN7,FNIP1,PEAR1,SEC14L1,ZFP30,FNDC3A,ST6GAL1,ANKRD6,SIRT2,COA1,CDK5RAP2,SNAP25,MBD5,ANKFN1,SNRPN,FAM219A,DOP1A,ERC1,UNC5B,IQSEC2,CDK19,CLASP2,ITPRID2,NKAIN2,DIP2A,SULF2,SYN2,COBL,ADGRL3,NEU4,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,HIF3A,RNF216P1,SIRT1,AP4E1,SLC44A1,THRA,TMPO,PIK3R5,NPL,SYNPO2,TRIO,TSC1,UBE3A,ZNF189,SLC30A3,EMSY,HPS4,UBE3B" MicroRNA hsa-miR-4305:mirSVR_lowEffct hsa-miR-4305:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-80 1.16E-76 1.64E-79 1.51E-78 200 1101 "VWA5B2,ABHD6,ACTN1,ADD2,ADRB2,KLHL13,HACE1,C1QTNF3,SMIM17,ALCAM,BBOX1,DPP10,C6orf89,SPTBN4,ZBTB10,CHID1,EIF4G3,RNF182,ATP6V0A1,DST,LDLRAD4,CACNA1B,KALRN,PTBP2,USP6,SEPT7,TIGD7,CHN2,LHX2,ABCG2,QKI,SRP14-AS1,SLC4A8,RCHY1,SEC31B,GDA,LRIG1,CSNK1E,DZIP3,PPP1R16B,ERC2,CTH,PUM1,CCDC144A,KIAA0408,HDAC9,ARHGAP32,KCTD8,IP6K1,ELMSAN1,ZNF804A,MYEF2,ZC3H11A,WDR20,ZNF582-AS1,GRIN3A,DMD,CD99L2,SLC12A6,DPYSL2,GOLT1B,E2F5,AASDH,FCF1,KLHL5,FRY,PHF20L1,EIF4G2,EPB41L2,EPHB1,CEP85L,ANKMY1,EYA1,ABCA8,NSRP1,CEP78,OLFM1,FGF11,SLC37A3,PDLIM5,FAM49B,ATP2C1,ERGIC3,STAU2,BRSK1,ABLIM2,FYN,GABBR1,GABRG1,ZNF234,SEPT9,GCNT2,CRCP,SPIN1,MSL3,LILRA2,GPR12,GSN,MAP4K5,BACH2,ELOVL5,IDH3A,LRRCC1,IL6R,GATD1,KIF2A,LAMP2,MATN3,TM6SF1,MSR1,MYO9A,ZNF862,NF1,SLC11A2,NTRK2,TBC1D25,IGSF11,DPY19L2P2,PRTG,OLA1,ABCB1,LRP12,SCHIP1,MAGEL2,SH3KBP1,PPP2R5E,PRKACB,MAPK9,GDPD1,RELN,MTMR10,SPDL1,TMEM260,ZSCAN32,PTPRE,RBBP6,RADX,ZDHHC14,GTDC1,ZNF532,CCDC25,FBXW7,ATP8B4,LRRK2,ATXN2,FNDC3A,ANKRD6,SLC2A5,PPP4R3A,KANSL3,SLC6A11,CPEB4,GKAP1,ANKRD36,FNBP1,SPP1,KDM4C,ATP10B,ZSCAN29,RGL1,DIP2A,ADHFE1,STXBP1,PRRC2C,MCF2L,SATB2,ZEB1,TRIM2,USP22,PCDHB9,PCDHB4,USP32P1,TNS2,SLC44A1,GALNT17,ARL10,ERCC6L2,TP53BP2,NPL,RGMB,TRPS1,TTTY15,HIRA,UGT8,BCL2L13,CLDND1,ZBTB14,ELFN1,ATP6V0E2,REEP1,TMEM198,DPYSL5,STOX2,MDH1B,NAV3,EPM2A,HNRNPA3,RSPRY1,NLRP3,FAM198A" MicroRNA hsa-miR-196a:mirSVR_lowEffct hsa-miR-196a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.08E-80 1.16E-76 1.65E-79 1.52E-78 215 1272 "CLK4,ACTN1,GALNT16,GALNT13,USP31,ADRB2,BEND6,HECW2,PCDH19,OSBPL1A,KIAA1324,AK2,ALCAM,ARHGAP20,FAM135A,DOC2A,AMPD2,AMPD3,EP400,LCORL,LGR5,IGDCC4,CASK,CDK13,ZBTB10,CHRD,TMEM108,ATP1B3,TTLL9,BACH1,CFLAR,KSR1,GYG2,CACNB4,CAST,CLDN10,METTL6,CD86,DGKI,SEPT7,SRSF11,ASIC3,B4GALT6,NDST3,PLAA,TPP1,ABCG2,C4orf33,SRP14-AS1,AKAP7,LETMD1,SLC4A8,AHCTF1,SMARCAL1,CS,RGS6,VAC14-AS1,FAM169A,DZIP3,PPP1R16B,APPL1,UBXN2A,GAPVD1,ZFYVE16,ELMSAN1,ZBTB24,SLC29A4,DOCK2,DMTF1,ECM2,E2F5,AASDH,EBF1,HIPK3,RASGRP1,TMTC1,APH1A,ASB3,EIF4G2,DCTN4,USPL1,GPHN,RABEPK,SRRM1,ARMCX1,CHST15,ZNF589,SUCO,AGAP2,SYNCRIP,NELFCD,FOLR2,JKAMP,FAM49B,ATP6V1H,ZNF605,C15orf41,GATM,TUBGCP4,SULT1C4,CRCP,PRUNE2,CCDC184,CNTRL,RNFT2,RASSF8,HAS2,MAN1B1,ATXN2L,AGBL5,ZNF491,ZDHHC15,CELF5,FAM95B1,C2orf72,NKD1,SLC35G1,KCNJ5,KCNN2,STXBP5,MAT2A,MBD1,AFDN,MXI1,MYO6,ALDH1L2,NME4,NOVA1,NPR2,IGSF11,OGG1,P2RX7,ETFRF1,PCDH8,PCSK5,PFKFB3,SERPINI1,CCSER2,ING3,MAPK9,MASP1,RELN,GDPD2,PIGG,BDNF-AS,PTK2,PTPRB,TUG1,ZDHHC14,RDX,RET,CARF,PCMTD2,ZNF671,MCMBP,KCNIP3,CLIP1,SEC14L1,FOXRED1,TRA2B,COPZ1,CPEB3,FNDC3A,ANKRD6,DHX30,TRIM67,MAST1,MBD5,PDZRN3,DOP1A,SOX11,MYCBP2,PEG10,TSPYL2,LARP4,CEP68,ADHFE1,SYNE2,VPS13A,SYP,COBL,ANKRD28,MTCL1,CUX2,TPCN2,TRIM2,RPGRIP1L,SYNE1,DOCK9,TNS2,HIF3A,RNF216P1,DICER1,KHDC1,ZNF106,AKTIP,KAT6B,NPL,NR2C2,ZNF610,UGT8,WIPF1,RICTOR,XPO1,ZBTB14,ZNF24,ZNF28,KCNT2,CELF4,DHX33,PPP1R3F,PARP11,PHTF2,SOCS4,JPH3" MicroRNA hsa-miR-519d-3p:TargetScan hsa-miR-519d-3p TargetScan 2.25E-80 1.26E-76 1.78E-79 1.64E-78 188 971 "NCKAP5,RNF150,PTCHD1,ADRA1B,APBB2,MARK4,RASL11B,ATP2B2,MPDZ,BID,ARHGEF7,MTMR3,JAZF1,DLGAP2,CFL2,B4GALT6,QKI,PCYT1B,ARMC8,AHCTF1,CLOCK,C2CD2,ENTPD4,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,APPL1,PLCXD3,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,RASSF2,IP6K1,GIT2,DNAL1,MFAP3L,FBXL5,SACS,DPYSL2,DNAJB6,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,CERCAM,RGS17,MTSS1L,ETV1,DNAJC27,KATNAL1,EZH1,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,RAB30,GPD2,GPR37,ATE1,CIT,BVES,FICD,ATOH8,HAS2,MIER3,HLF,MSL1,IL6ST,ITPKB,KCNB1,KIF5A,KPNA5,CAMK2N2,HECTD2,CHIC1,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,OCRL,GPR137C,PDE1B,PFKFB3,PIK3R1,CCSER2,PKD1,PURG,LRP12,POU6F1,PPARA,PRKACB,PKIA,MAPK4,FITM2,CNNM2,PSD,PTPRD,MARCH1,CEP97,FAT4,OXR1,RASGRF2,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RPS6KA2,SALL1,SATB1,CSRNP3,SCN2B,GALNT10,FAM102A,CPEB3,CHD9,FNDC3A,BTBD7,MBD5,CMTR2,FAIM2,FAM126B,ERC1,ARHGAP26,IQSEC2,LMO3,CAMTA2,RGL1,DIP2A,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DOK6,RGMB,NR2C2,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-125b-2*:mirSVR_highEffct hsa-miR-125b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.39E-80 1.34E-76 1.89E-79 1.74E-78 201 1113 "KCNH8,CCDC85A,PWWP2A,PTCHD1,ZNF608,HFM1,C1QTNF3,SPARCL1,ALCAM,FAM135A,AMPD3,CDC42BPA,LRCH2,CCDC146,RASL11B,RNF182,DPY19L3,CFLAR,SYNJ1,SCAPER,SGCE,CA12,CACNA1B,THSD7A,PTBP2,CAST,CBS,KRIT1,USP2,SLC16A4,C1orf52,DGKI,CCPG1,CHN2,MS4A7,RAB28,PPT2,CLTC,NGEF,AKAP7,ARMC8,SLC35F1,CRMP1,C1QL2,GDA,RGS6,CSNK1G3,CST3,DZIP3,APPL1,PHF14,USP6NL,BOC,MYEF2,KLHL3,SV2B,CPEB2,E2F6,EDNRA,PHC2,PHF20L1,PLEKHA1,CALCRL,USPL1,GPHN,SRRM1,VPS26C,ARMCX1,ACSL4,PTK2B,DLC1,GORAB,FGF1,HPCAL4,FOXF2,VTI1B,NELFCD,JKAMP,ZNF605,DLL3,GABRB3,ZNF234,ERAP1,ZNF559,NEU3,ARFIP1,SESN1,COPS8,DBF4,GLYR1,RAB30,CCDC184,PRDM5,PSIP1,HMGCR,IRF8,ZIC5,RBPJ,SLC35G1,METTL21A,KCND2,KPNA5,STMN1,HECTD2,MARK1,MATN2,AFDN,MSR1,MXI1,CCDC13,NTRK2,OCRL,PCDH8,PCDH9,PDE4D,GPR85,PLIN1,PURG,PDZRN4,PSAT1,SCHIP1,SEPT4,EPB41L4B,PRPSAP2,VPS13C,QRICH1,TMEM260,PTPRO,SH3TC2,FAT4,OXR1,RADX,PBRM1,TMLHE,GSTCD,CLIP1,RTN1,RYR3,FAM192A,ZFP30,PPP4R3A,EPN2,SLC6A11,SEPHS1,SLC12A2,SLC22A4,CPEB4,SNCA,TMCC1,MYO16,FNBP1,DOK5,KDM3A,SP2,HECW1,MYCBP2,KDM4C,ZC3H13,ERBIN,NXT2,SEPT8,SYNE2,VPS13A,SYN2,ANKRD28,TACC1,TACR1,EXOC7,TCF4,CLASP1,FRYL,SIK3,SIRT1,ZFPM2,AKTIP,RIMBP2,SYNPO2,PPIL6,TTC3,CLHC1,HIRA,UCHL1,UGT8,BCL2L13,CCDC14,VLDLR,WIPF1,ZIC1,MKRN3,TCEAL7,ZFAND5,SMARCAD1,SLC30A3,CADM2,NAV3,RGS7BP,FAM13C,KAT6A,SMIM8,MSRB3,FRMD6" MicroRNA hsa-miR-488*:mirSVR_lowEffct hsa-miR-488*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.64E-80 2.03E-76 2.87E-79 2.64E-78 238 1554 "SLC24A4,AP2A2,ZNF608,PCDH19,SYT13,AMPD2,AMPD3,LRFN1,LRCH2,APC,PRX,IGDCC4,CADPS,SLC2A11,TTLL9,RGS9,ARHGEF7,GPC2,KALRN,RUNX1T1,CBLN1,CLDN10,CDH2,LRRFIP1,CCPG1,SRSF11,CHN1,TAOK2,NRXN3,PPT2,CNR1,CNTN1,IQCK,AKAP6,COL9A1,RBM39,AKAP12,RNF14,SNCAIP,LRRC3B,VCAN,SOCS5,PDE4DIP,CNTNAP2,UBXN2A,GREB1,USP6NL,BOC,RIPOR2,DCAF8,LONRF1,MATR3,KIAA0586,MAML1,DGKB,SPOCK2,IP6K1,DBI,YTHDC1,MFAP3L,TMEM130,LYPD1,RHOBTB1,SNAP91,WDR20,EXOG,CASP8AP2,FAM78B,E2F6,AASDH,EDNRA,KLHL5,FAM13A,PLXNC1,RGS17,CALCRL,PAN3,EPHB1,RABEPK,DENND4A,F5,FAM198B,ZNF461,FCGR1A,FKTN,ZNF589,FGF13,SUCO,SYNCRIP,EVL,ANKFY1,NBEA,TPK1,ATP6V1H,ZNF605,MSANTD4,MEGF11,TRAF3IP2,B4GALNT1,RAPGEF6,ZNF274,IP6K3,IQGAP2,C15orf41,IGSF5,MSTN,NFU1,ADAM28,GGTA1P,GGT7,GHR,LYVE1,TOX3,TNRC6A,LUZP2,DCLK2,GPD2,DIDO1,FAM19A2,RNF165,BVES,SOX21,HAS2,MAN1B1,ZDHHC15,MSL1,IDH3A,IBA57,INPP5B,SLC35G1,KIF2A,KIT,LAMP2,MAP4,MATN3,CHIC1,KCTD6,PPM1L,ZNF680,BLOC1S2,N6AMT1,MYH3,LAYN,MYO9A,ZNF862,HNRNPM,NF1,NOVA2,NPR2,CLDN11,TREM2,CNTN3,PDE4D,SLC10A4,CCSER2,KCTD15,PDZRN4,LRP12,PPM1B,PRKCB,NDUFS7,PTPN13,PTPRB,PTPRE,TTC13,MARCH1,NWD1,KHDRBS2,CCDC82,ALG9,CARF,NEK11,SPIN3,GLDN,AP1AR,SALL1,CSRNP3,SCP2,SEC14L1,KIF21A,FBXO11,FNDC3A,NLGN1,PPP4R3A,PKNOX2,SLC6A11,CCDC88A,SLC9A5,ATF7IP,CPEB4,MBD5,LMBRD1,PDZD2,MCF2L2,NFASC,ZC4H2,SEPT8,DIP2A,STX1A,KLHL7,VPS13A,PLCB1,TACC1,PJA1,TBCEL,FBXW11,TCF4,DMXL2,SATB2,CLASP1,DOCK9,FAM189A1,PCDHB4,PCDHA5,FRYL,PMS2CL,DICER1,AP4E1,SLC44A1,RUSC1,CA14,FAM155A,FLRT2,ZNF24,ZNF540,CRB2,REEP1,TMEM237,LAMP5,GAL3ST3,FIP1L1,RGS7BP,FZD3,PHTF2,CASC15,FAM219B,JMJD1C,CPNE4" MicroRNA hsa-miR-150*:mirSVR_lowEffct hsa-miR-150*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.65E-80 2.04E-76 2.88E-79 2.65E-78 229 1443 "ASPHD1,ACADM,SYS1,KDM5D,NDRG3,KLHL32,TMCC3,PLEKHH1,BEND6,SORCS2,C1QTNF3,LTBP4,ALK,SYT13,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,CPNE5,SPTBN4,ARNTL,CDK13,TMEM108,STX16,RNF182,RIPK1,LINC00847,DST,MTMR2,CA12,CACNA1B,KALRN,SPAG9,CBS,LDB2,COPB2,SOCS6,MS4A7,NDST3,IGLON5,AKAP6,RTTN,CNRIP1,CDC42BPB,PREPL,AKAP12,HINFP,ANKRD44,GDA,RGS6,OSBPL3,SOCS5,RASGEF1C,PLCXD3,PUM1,CCDC144A,CYBB,ARHGAP32,ZFYVE16,EARS2,IST1,TMEM170A,KIAA0319,POM121,SNAP91,WDR20,CD99L2,NR1D2,DPH1,SLC25A18,DTNA,ECM2,E2F5,SNX29,EDNRA,MBNL2,RASA4,KCTD3,EIF5,IRAK4,PAN3,DCTN4,EPB41,EPHB1,ETV1,ANKMY1,RASL12,REEP2,CEP78,KAT8,FGFR1,AMOTL2,RGPD5,FOXO3,COQ5,EFCAB2,UFM1,FAM49B,MPP6,ZNF234,MTHFD2,DISC1,PPARGC1A,MALT1,STARD3,HTATSF1,ZNF782,PRUNE2,TMEM121B,PCLO,ADAMTS13,CIT,CLASRP,RNF165,RNFT2,HNF4G,ICA1,MSL1,IDH3B,IGF1,SLC35G1,CAMK2N2,MAN2A2,MAP2,MAT2A,MBNL1,KITLG,GIT1,COL28A1,MYCN,LYRM9,MYO6,MYO7A,NBL1,NEFM,NF1,CNOT4,DNHD1,SETD4,CHAMP1,OGG1,PDE4A,CCSER2,PKD1,PCDH18,PLTP,ANKRD16,PMP22,LRP12,SCHIP1,SEPT4,PPARA,MINDY2,CCDC144B,KANSL1,VSTM2L,PRKACB,PIGG,PTN,TMEM260,PTPRB,PTPRD,PTPRE,C1orf109,PTX3,STRC,RAD51D,RASGRF1,RDX,TRIM68,ZFHX4,ZNF532,RPL15,ARMH4,BAALC,GLDN,MEG3,RTN1,NCBP3,FAM192A,RMI1,SUPT20H,TRA2B,AMBRA1,ST6GAL1,SYBU,SLC2A5,SLC12A2,IFT122,PDZRN3,KDM4B,USP33,KDM3A,KDM4C,TEX2,IQSEC2,SPART,STX1A,SULF2,PRRC2C,SIN3B,DMXL2,ZEB1,TRIM2,PHF24,HIF3A,SLC44A1,TMEM9,ACTR6,LRRC8A,TPM1,ZNF346,TRIO,STXBP4,HIRA,FLRT2,LAT2,DHX33,SLC30A4,EMSY,EVI5,STOX2,PDSS2,ST7,UBE3B,FBXO36,FAM219B,MSRB3,ST8SIA2,GAN" MicroRNA hsa-miR-23b:PITA hsa-miR-23b:PITA_TOP PITA 3.77E-80 2.11E-76 2.96E-79 2.72E-78 171 799 "ABHD6,SYS1,KLHL32,PCDH19,RTL9,OSBPL8,SRPX,ARHGAP20,MAP4K3,PKP4,APAF1,SHROOM2,PPP4R4,MADD,NCOA1,SLC4A4,SYNJ1,JAZF1,KALRN,RUNX1T1,CCK,DCLK1,LARGE1,DLGAP2,CFL2,SOCS6,NRXN3,CLCN3,QKI,MAP4K4,CNR1,ARMC8,COL4A5,AKAP5,RCHY1,ZNF521,IGDCC3,AKAP12,CS,LRIG1,CSNK1G3,PLCXD3,USP6NL,MAML1,POM121,WDR20,DLX1,RAB39B,MED12,CPEB2,DNAJB6,ABCC5,EGR3,KCTD3,TENM1,CALCRL,ERBB4,ETV1,EYA1,PTK2B,SPSB4,SUCO,VTI1B,FOXO3,FUT9,MEGF10,CHL1,C15orf41,GCNT2,ARFIP1,PPARGC1A,TOX3,TNRC6A,ADAMTS6,HAS2,ZHX1,BACH2,MIER3,HNF4G,NEGR1,ZIC5,IL6R,KCNK3,IPO5,CYP27C1,GPR155,MAP4,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MIA2,KITLG,MITF,MKLN1,AFF1,AFDN,MPP2,MSI1,HS6ST3,ZC3H12B,NEFH,PRTG,PDE4B,PDPK1,GNG2,OLA1,PIK3C2A,ZNF655,PPP2R5E,PKIA,CNNM2,ELOVL2,RBBP6,PRIMA1,PBRM1,ZFHX4,CCDC82,ROBO2,SNX22,SAFB,SEMA6D,SATB1,FNIP1,ZFP2,SEC14L1,SGK1,KIF16B,AMBRA1,FBXO11,WDR37,BTBD3,EPN2,SLC12A2,CPEB4,FAM126B,SOX11,HECW1,ZNF423,RBM26,POGZ,ZC4H2,NKAIN2,SS18,ERBIN,ELOVL4,SEPT3,CAMTA1,ATMIN,SATB2,ZEB1,TRIM2,PUM2,SIRT1,NACC2,WBP2,TRPS1,SSBP2,TBC1D15,VSNL1,ZIC1,MICU3,REEP1,TMEM237,SMARCAD1,EMSY,SLC38A1,PRDM10,WNK3,JMJD1C" MicroRNA hsa-miR-23a:PITA hsa-miR-23a:PITA_TOP PITA 3.77E-80 2.11E-76 2.96E-79 2.72E-78 171 799 "ABHD6,SYS1,KLHL32,PCDH19,RTL9,OSBPL8,SRPX,ARHGAP20,MAP4K3,PKP4,APAF1,SHROOM2,PPP4R4,MADD,NCOA1,SLC4A4,SYNJ1,JAZF1,KALRN,RUNX1T1,CCK,DCLK1,LARGE1,DLGAP2,CFL2,SOCS6,NRXN3,CLCN3,QKI,MAP4K4,CNR1,ARMC8,COL4A5,AKAP5,RCHY1,ZNF521,IGDCC3,AKAP12,CS,LRIG1,CSNK1G3,PLCXD3,USP6NL,MAML1,POM121,WDR20,DLX1,RAB39B,MED12,CPEB2,DNAJB6,ABCC5,EGR3,KCTD3,TENM1,CALCRL,ERBB4,ETV1,EYA1,PTK2B,SPSB4,SUCO,VTI1B,FOXO3,FUT9,MEGF10,CHL1,C15orf41,GCNT2,ARFIP1,PPARGC1A,TOX3,TNRC6A,ADAMTS6,HAS2,ZHX1,BACH2,MIER3,HNF4G,NEGR1,ZIC5,IL6R,KCNK3,IPO5,CYP27C1,GPR155,MAP4,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MIA2,KITLG,MITF,MKLN1,AFF1,AFDN,MPP2,MSI1,HS6ST3,ZC3H12B,NEFH,PRTG,PDE4B,PDPK1,GNG2,OLA1,PIK3C2A,ZNF655,PPP2R5E,PKIA,CNNM2,ELOVL2,RBBP6,PRIMA1,PBRM1,ZFHX4,CCDC82,ROBO2,SNX22,SAFB,SEMA6D,SATB1,FNIP1,ZFP2,SEC14L1,SGK1,KIF16B,AMBRA1,FBXO11,WDR37,BTBD3,EPN2,SLC12A2,CPEB4,FAM126B,SOX11,HECW1,ZNF423,RBM26,POGZ,ZC4H2,NKAIN2,SS18,ERBIN,ELOVL4,SEPT3,CAMTA1,ATMIN,SATB2,ZEB1,TRIM2,PUM2,SIRT1,NACC2,WBP2,TRPS1,SSBP2,TBC1D15,VSNL1,ZIC1,MICU3,REEP1,TMEM237,SMARCAD1,EMSY,SLC38A1,PRDM10,WNK3,JMJD1C" MicroRNA hsa-miR-921:mirSVR_lowEffct hsa-miR-921:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-80 2.46E-76 3.44E-79 3.17E-78 227 1420 "PLEKHH1,PTCHD1,HECW2,KLHL13,KIAA1324,TXNDC16,HFM1,AMPD2,AMPD3,EPB41L5,LGR5,SFMBT2,ARNTL,PLA2G4C,ATP2B2,DPY19L3,ATP6V0A1,CFLAR,KSR1,ARHGEF7,FUBP1,C5,LURAP1,KALRN,PTBP2,CAST,CBLN1,SLC16A4,CD38,ENTPD6,LRBA,CDH2,DCLK1,CCPG1,CACNA2D2,FOXN3,ASIC3,RAB28,PPT2,CLTB,CNTN1,LETMD1,COL11A2,AKAP5,BAG4,PREPL,CREM,RBM39,ANKRD44,GDA,CS,SNCAIP,RASGEF1C,SLITRK5,DZIP3,RIMS2,DCAF4,ARHGAP24,EARS2,RASSF2,GIT2,YTHDC1,WDR20,ZNF582-AS1,EXOG,GRIN3A,RAB39B,SLC29A4,DYNC1I1,CDON,DRP2,PDCD6IP,ECM2,MAMLD1,DNAJB6,DNM1L,EBF1,HIPK3,FCF1,RASGRP1,FSD1L,EIF1,VPS13B,KATNAL1,FAM198B,SCML2,FCGRT,FER,FGF1,OLFM1,FGFR1,POLK,HPCAL4,SYNCRIP,IQCG,NBEA,CAMKK2,ATP6V1H,CELF1,AP4B1,HRASLS5,CHL1,GABRG1,SIGLEC8,DBF4,ZNF638,GNG4,LNX1,PRUNE2,ATP2B1-AS1,BTN2A1,GSTM5,PSIP1,NXPH3,GABARAPL2,ZNF491,DHX35,C2orf72,ITPKB,JAK2,KIF2A,KTN1,HECTD2,MEIS1,AFDN,XRRA1,BLOC1S2,ADAM22,ZC3H12B,NEFM,CCDC13,NTRK2,DPY19L2P2,SEMA5B,ZNF655,SNX10,XRN1,KCTD15,GPSM2,PMP22,PPP2R5E,RANBP3L,MAPK9,KLK6,BCAS3,ELOVL2,PTPN13,C1orf109,ZSCAN2,OXR1,RDX,REV3L,PRRT2,RIC8B,PBRM1,RNASEL,CCDC82,ZNF532,ROBO1,RORB,RPL15,MCMBP,TCP11L1,ABCA11P,ATAT1,SALL1,ATXN2,FNIP1,SEC14L1,FAM102A,CHD9,SLA,FAM81A,KANSL3,SNRPN,ZSWIM8,SPP1,ZC3H13,SSTR2,ZSCAN29,DIP2A,RHBDL3,VPS13A,PLCB1,SYPL1,CAMTA1,DNMBP,KLHL4,TCEA1,SATB2,CUX2,TPCN2,RPGRIP1L,DOCK9,HIF3A,DICER1,DICER1-AS1,ZFPM2,C18orf54,THRA,RIMBP2,R3HDM1,TRIO,AMACR,TSC1,PLEKHH2,VLDLR,LMF1,ZNF781,XRCC4,PCDH20,MICU3,KCNT2,LYPD6,SH3GLB2,DHX33,EMSY,NT5M,GDPD5,STOX2,EPM2A,FAM13C,MARCH8,HNRNPA3,PHTF2,JMJD1C,CPNE4" MicroRNA hsa-miR-144-3p:TargetScan hsa-miR-144-3p TargetScan 4.62E-80 2.59E-76 3.62E-79 3.33E-78 166 751 "ELFN2,CCDC85A,AXIN2,OSBPL1A,ALCAM,PCDH10,BEGAIN,DPP10,ANK2,PPFIA4,APC,CASK,MARCH3,ATP2B2,KSR1,BMPR1B,DST,MTMR2,LDLRAD4,CACNA2D1,CALB1,CBFA2T2,CDH2,NOG,CFL2,CHN2,LHX2,QKI,CNN3,C2CD2,HAPLN1,PPP1R16B,PUM1,CCDC144A,PYGO1,HDAC9,JAKMIP2,MYEF2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,DTNA,EBF1,HIPK3,PHF20L1,EGFR,MBNL2,PLXNC1,GOLGA7,EIF4G2,EIF5,RGS17,ELN,EPB41,MTSS1L,ERBB4,ETV1,ACSL4,DLC1,MED12L,PSD2,DCTN2,CAMKK2,ATP2C1,KHDRBS3,AHDC1,GLI2,RAB30,GNAL,KAT7,FAM222A,BACH2,MIER3,HMGCR,AGFG1,HSF2,JAK2,CDH20,KLHL23,KCNN3,KIF2A,KIT,CYP27C1,LIFR,NCOA7,LSAMP,MARK1,MATN2,MBNL1,MEIS1,MEIS2,KITLG,MITF,MSI1,MYCN,MYT1,NFE2L2,NOVA1,NPTX1,CNTN3,PCSK5,PDE4A,PDE4D,GPR85,PIK3C2A,PCDH18,PPP2R5E,PKIA,PTCH1,FAT4,RASGRF1,KHDRBS2,REV3L,FIGN,RFX3,NUDT11,PBRM1,ROBO2,RORB,FBXW7,SALL1,SCN8A,CPEB3,FNDC3A,BTBD3,EPN2,CCDC88A,ATF7IP,CXXC4,LIMCH1,FAM126B,KDM3A,ARHGAP26,CDK19,LMO3,RGL1,PRRC2C,ADAMTS17,ANKRD28,ANKRD12,MCF2L,FBXW11,MGRN1,RPGRIP1L,NSD1,PUM2,CRTC1,GPRIN3,FRYL,NACC2,KAT6B,RASD2,DOK6,RGMB,FLRT2,KCNK12,NDRG4,DPYSL5,NAV3,KAT6A,PHTF2,ADAMTSL3,NETO2" MicroRNA hsa-miR-34b*:mirSVR_highEffct hsa-miR-34b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.95E-80 2.77E-76 3.87E-79 3.56E-78 197 1073 "NDRG3,ADCY6,ADD2,ADORA2A,ZNF608,KCTD16,KIAA1324,ZNF578,TAOK1,ALCAM,FAM135A,AMT,ANK2,TMEFF1,LINC00173,ZBTB10,ATP1B3,DOCK11,ADAM23,BACH1,CFLAR,SYNJ1,JAZF1,WASF1,CACNA1A,CALB1,THSD7A,PTBP2,SPAG9,CD86,DGKI,DCLK1,MAGI1,DLGAP1,B4GALT6,LHX2,CLTC,FAM19A5,SULT4A1,HECTD1,PREPL,CREM,ENTPD4,NCOR1,SIPA1L1,SOCS5,APPL1,PNPLA8,PUM1,PPP6R2,USP6NL,TBC1D5,TMEM170A,GIT2,ELMSAN1,KLHL3,USP3,DPP6,ECM2,DNM1L,E2F5,EDIL3,SNX29,SEMA3D,FSD1L,CELSR3,APH1A,TENM1,PLEKHA1,CALCRL,VPS13B,LRRC17,GPHN,NRN1,FAM198B,FDFT1,POLK,RGPD5,C2orf88,WDR83,FAM49B,STAU2,MSANTD4,IQGAP2,TUBGCP4,MSTN,GPD2,FUT10,ELOVL5,AGFG1,SHISA6,ZIC5,INSM1,ITPKB,KCND2,KTN1,LAMP2,PAXBP1,SYTL4,LSS,CLEC18A,MAN2A2,MAT2A,MATN2,MBP,MEST,MITF,MYCN,MYO9A,NEK1,CNOT4,CNTN3,ABCB1,PIK3C2A,XRN1,JAKMIP1,PLIN1,EXOSC10,ING3,SEPT4,MAPK4,DCHS2,MASP1,APTX,ELOVL2,PTPRG,QDPR,USP47,RDX,FIGN,RGS4,SLC25A36,RIC8B,TMLHE,SPIN3,ATP8B4,ATAT1,RYR3,SCP2,HSPA4L,SHC4,ANKRD6,PPP4R3A,DMRTC1,CDK5RAP2,SNRPN,MYO16,FAM219A,HECW1,MYCBP2,SPP1,ZC3H13,CDK19,ITPRID2,ZC4H2,ERBIN,ZSCAN29,SULF2,ZC3H4,VPS13A,SYT1,MTCL1,FAM208A,ATMIN,TPCN2,TRIM2,SYNE1,GPRIN3,DICER1,TLR4,LRRC8A,RIMBP2,TPM2,DCBLD1,KCNE5,TSN,TTC3,UBTF,WIPF1,CLDND1,RICTOR,ZNF540,ZNF74,FSTL5,ZNF184,ANKS1B,CADM2,DNALI1,ADAMTS9,NAV3,FAM47E,PHTF2,FBXO36,JMJD1C,NHSL1,NETO2,NETO1" MicroRNA hsa-miR-197:mirSVR_lowEffct hsa-miR-197:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.02E-80 2.81E-76 3.92E-79 3.61E-78 244 1632 "DGCR6,ACADM,ADCY6,UNC5A,SEMA6A,PCDH10,FAM135A,AMPD3,ZFAT,CDC42BPA,DPP10,ANK2,FGD2,UPRT,PPFIA3,SEMA4G,PPP4R4,EIF4G3,RNF182,ATP6V0A1,RIPK1,ADGRB3,MPDZ,CFLAR,KSR1,GYG2,CACNA1G,CABP7,DGKI,LRBA,CDH2,ZMYM4,LOC730101,CRLF1,RCBTB2,SULT4A1,SRP14-AS1,MAP4K4,AKAP7,AKAP6,ABI3BP,COX4I1,AHCTF1,SMARCAL1,ANKRD44,GDA,ARHGEF10,SLITRK5,DZIP3,GREB1,RUBCN,GPRASP1,DCAF8,IST1,TMEM170A,KLHL3,DDX46,SACS,KIF19,DNAH9,DOCK2,ACOT8,RCAN1,MAMLD1,ABCC5,DNM1L,EDN1,YAF2,APH1A,EGR3,RASA4,KCTD3,EIF4G2,ING4,DCTN4,RABEPK,SLC43A2,IGSF6,RPS6KC1,FGFR1,BAIAP2,SYNCRIP,RGPD5,NELFCD,NBEA,SARAF,CHL1,GALC,KIAA1841,GATM,SULT1C4,GGT7,TOX3,MSL3,CBX1,DCLK2,LILRB4,GRB10,DIDO1,RNF165,GSTM5,AP4S1,MAP4K5,PADI2,FRMD3,HLF,IDH3B,MYLK2,SCIN,INPP5B,ITPKB,SLC35G1,METTL21A,KCND1,CREG2,LINC00634,HECTD2,MAP4,MAPT,MARK1,MBD1,MBNL1,CHIC1,TM6SF1,MIA2,PTOV1,MX1,LYRM9,SFR1,VWA2,CNOT4,SLC11A2,NTRK2,SETD4,OCRL,OPRL1,ZNF827,PFKFB3,PLXNB1,PURG,ANKRD16,SCHIP1,MAGEL2,LRRN3,PPP3CA,SLC26A11,PRPH,SAMD9,VPS13C,PIGG,PTCH1,BDNF-AS,ZIK1,EML5,PTPRG,PPP2R3C,GAL3ST4,GTDC1,FIGN,PBRM1,EXD2,ARMC5,CARF,ROBO2,SNX22,ZNF568,ZNF331,RMI1,MAPK12,ATXN7,SCAF8,KIF21A,PPM1E,HKDC1,FBXO11,FHOD3,NUBPL,SLA,DHX30,FAM214B,SLC6A8,ZNF430,CDK5RAP3,SLC9A5,SLC12A2,ATF7IP,SLC22A4,ZNF667,CDK5RAP2,LIMCH1,MBD5,SNRPN,FAM126B,MYO16,BDP1,SPP1,PEG10,TSPYL2,RBM26,ATP10B,CLSTN2,SSPO,ZSCAN29,ELOVL4,STXBP1,ZC3H4,SUPT5H,DNAJC9,SYN1,SYN2,EXOC7,TPCN2,TCF12,SZT2,ARHGAP9,CYB561A3,AP4E1,SLC44A1,TLR4,NPL,TPM2,STXBP4,NUTM2A,RUSC1,ZKSCAN5,SLC35A4,BCL2L13,P2RY12,GUSBP1,LGI4,SLC47A2,TRIM9,NDRG4,MKRN3,ZNF138,AMZ1,EML6,ZXDA,CIAPIN1,PPP1R3F,WNK3,TTC7A,IFT88,CPNE4" MicroRNA hsa-miR-3122:mirSVR_lowEffct hsa-miR-3122:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.98E-80 3.35E-76 4.67E-79 4.30E-78 225 1398 "CLK4,TMEM132B,BRAP,PWWP2A,PTCHD1,ADRA1D,OSBPL1A,AK2,ZNF578,C1QTNF1,SEMA6A,SYT13,LRFN1,CCDC146,APLP1,VAT1L,TNRC6C,USP37,STK33,NUMB,SLC2A11,DPY19L3,BACH1,ADGRB2,CFLAR,ARHGEF7,CACNB4,CALB1,CBR1,KRIT1,CERS5,AP4M1,CDH2,LRRFIP1,NOG,CHN2,STOML1,RAB26,COL9A3,NECTIN3,SEC31B,CLOCK,PREPL,CREM,CRMP1,CLIP3,SNCAIP,VAC14-AS1,PLXNA4,CTH,KIAA0408,ARHGAP32,AIF1L,ELMSAN1,MYEF2,ELMO1,GSDME,GRIN3A,DMD,SLC12A6,DTNA,AASDH,EDN1,CNNM1,TNK2,EMX2,EPHB1,CEP85L,DLC1,CHST15,FKTN,GTF2IRD2,FGF13,POLK,SUCO,PDLIM5,FAM49B,RASL10A,ABLIM2,IQGAP2,C15orf41,GCK,GCNT2,CYP46A1,MMADHC,MALT1,ZNF276,GLI2,MSL3,GPT2,PRUNE2,FUT10,BVES,AP4S1,FAM107A,GUCY1B1,ATOH8,ARHGAP36,AGBL5,SHISA6,EID2B,IRF8,MYLK2,ZNF678,KCNK3,CREG2,A1BG-AS1,TTYH2,SFXN5,PAXBP1,ASPRV1,MAPT,MATN3,MBP,TM6SF1,MEIS1,MEIS2,KITLG,AFF1,MN1,ZNF92,NEFH,NFYA,VWA2,SMIM11A,IGSF11,OCRL,PDE4A,ENPP2,FAM98B,GPSM2,MTRF1L,PURG,PNMA3,TRHDE,MAPKAP1,LRP12,PSAT1,NKAIN4,PRKACB,DCHS2,VPS13C,PTN,C1orf109,TUG1,SUSD4,NWD1,OXR1,HKR1,RDX,GTDC1,RFX3,RGS3,EXD2,RPE,FBXW7,SPIN3,GLDN,ADAL,NCBP3,ZNF331,SEMA6D,ATXN2,SCP2,SEC14L1,KIF21A,KIF16B,CHD9,CCDC92,SLA,KDM4D,SMARCD3,MAPKBP1,ZSWIM8,TSPYL2,CLASP2,NKAIN2,SSPO,STAU1,SEPT8,ADHFE1,NSFL1C,PLCB1,COBL,TAL1,KLHL4,ZFP90,ZEB1,NAT16,NSD1,PUM2,ARHGAP9,FRYL,RNF175,CYB561A3,DICER1,TIAM1,ERCC6L2,CSMD1,CDK20,STXBP4,TRPS1,TSC1,SSBP2,GORASP1,PLEKHH2,CCDC14,XRCC4,ZNF74,NDRG4,ZNF138,FTSJ1,MAP3K12,TMEM178A,PCBP4,RGS7BP,DOCK8,UBE3B,HNRNPA3,FBXO36,CASC15,KLHDC1,FRMD6,NETO1,DPF3" MicroRNA hsa-miR-302f:mirSVR_lowEffct hsa-miR-302f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.63E-80 4.27E-76 5.94E-79 5.47E-78 245 1648 "ACADM,ABHD6,NCKAP5,CCDC85A,PLEKHH1,USP31,KIAA1211,ESYT2,SLC24A4,OSBPL8,TXNDC16,CC2D2A,UNC79,TRMT9B,DPP10,ZFYVE28,CDK13,PDE8B,STK33,N4BP2L1,DPY19L3,ATP6V0A1,BACH1,BBS2,BCL7A,BMPR1B,FUBP1,MTMR2,SGCE,CACNA1G,KALRN,CAMK2G,VXN,CH25H,ISPD,MTMR7,CFL2,FOXN3,NDST3,ABCG2,QKI,FAM149A,SUMF2,COL11A2,AKAP5,ABI3BP,RCHY1,BAG4,CPS1,GDA,CS,SOCS5,PLCXD3,CCDC144A,DOCK4,LONRF1,PITPNC1,JAKMIP2,MYEF2,RHOBTB1,SNAP91,SACS,SPOCK3,FAM107B,DMD,CD99L2,CDON,DRP2,DTNA,MAMLD1,DNAJB6,AASDH,EDIL3,EDN1,PHC2,HIPK3,RASGRP1,FSD1L,SUGP2,MBNL2,KMT5B,EGR3,RASA4,KCTD3,CALCRL,EPB41,SLC43A2,ETV1,ADGRV1,EYA1,ABCA8,SH3YL1,RACK1,ST3GAL6,PRKAG2,POLK,IP6K2,C2orf88,FAM49B,TRIM16,ATP6V1H,TVP23A,MEGF10,GAA,ZNF274,IQGAP2,TUBGCP4,SESN1,PPARGC1A,COPS8,GLI2,ZNF638,GPD2,GPR37,PCLO,GRM8,GUCY1A1,GUCY1B1,IRAK3,ZHX1,NEGR1,ZNF546,RBPJ,INPP5B,KLHL23,KCNJ16,KIT,LMO2,LRP1B,PPM1L,MITF,SAMD5,NOVA1,NUCB2,LOC100128398,CNTN3,PAX6,PCSK1,CDK18,GPR85,GNG2,ZNF655,XRN1,PCDH18,SCHIP1,ING3,RANBP3L,PRKACB,SNRK,ELOVL2,PTK2,PTPRB,PTPRN,RIPOR1,RAP1GDS1,ENOX1,ZMAT4,RFX3,DCUN1D2,ROBO1,EPHA10,FBXW7,ATP8B4,LRRK2,CSRNP3,ATXN7,PRCD,CASC3,GALNT10,STUM,SUPT20H,CHD9,FBXO11,ST6GAL1,SYBU,PPP4R3A,KANSL3,SLC6A8,SLC8A1,SLC12A2,MYH15,MBD5,FAIM2,DOP1A,ZNF423,ZC3H13,RBM26,ZNF621,SS18,NXT2,ZSCAN29,DIP2A,PRRC2C,PLCB1,CAMTA1,FAM208A,MGRN1,TRIM2,RPGRIP1L,TCF12,DOCK9,PHF24,SLC19A3,PCDHB3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZMAT3,ARL10,ASXL3,KAT6B,TPM1,NR2C2,SYNPO2,PDSS1,TRO,STXBP4,TRPS1,TSN,FAM155A,SLC35A4,WRN,CFAP298,POLR3H,ZNF189,FTSJ1,LAMP5,ZFAND5,SLC38A1,RNF103,SLC17A7,TRIM16L,DOCK8,RTN4,TRAM2-AS1,NETO1,ST8SIA2,GAN" MicroRNA hsa-miR-770-5p:mirSVR_lowEffct hsa-miR-770-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.89E-80 5.53E-76 7.70E-79 7.09E-78 228 1438 "RALGAPA1,ACADM,KLHL32,OSBPL8,UNC79,FAM135A,BEGAIN,AMPD2,EPB41L5,IGDCC4,ZFYVE28,ARNTL,MARCH3,ZBTB10,NUMB,BACH1,MIR9-3HG,CACNA1I,CABP7,PTBP2,CAST,USP6,CD86,SCARB1,CDH2,CDO1,DIS3L,SRSF11,NDST3,CLCN3,CLTC,ABCG2,SULT4A1,WHRN,SUMF2,ZNF521,CNRIP1,CS,ARHGEF10,SLITRK5,ERC2,PHF14,PNPLA8,USP6NL,ARHGAP24,DAPK1,ELMO1,TIAM2,RUSC2,KIAA0319,ALKBH8,PLPPR4,RAB39B,DMD,ECM2,TOM1,DNAJB6,ABCC5,KRBA2,E2F5,EDNRB,ANKRD46,FAM13A,PHF20L1,MBNL2,GOLGA7,CALCRL,EIF1,MFSD10,LRRC17,ZNF549,EYA1,TMEM132C,TUBB3,FER,FGF13,FGF14,FGFR1,BAIAP2,SUCO,IP6K2,FLT1,APOPT1,TPK1,ZNF605,KHDRBS3,OGA,ZMAT1,ZNF274,C15orf41,KIAA1841,GCNT2,SESN1,ADAM28,MALT1,ZNF638,MAP7D2,GPD2,DIDO1,ADAMTS13,HAS2,MAN1B1,SHISA6,SMAP1,ZNF181,GAREM2,RBPJ,ZNF678,JAK2,SLC35G1,KCNN2,LAMP2,PACRG,MATN3,MBD1,MEIS1,KCTD6,KITLG,N6AMT1,MX1,MYCN,NACA,NELL2,NFE2L2,NINJ2,NNAT,NOVA1,NPR2,SMIM11A,NTRK2,NUCB2,ENPP2,CYTL1,SEMA5B,PIK3R1,ZNF655,PCDH18,MTRF1L,PURG,LRP12,EXOSC10,PPARA,NKAIN4,SAMD9,PTCH1,PTPRB,PTPRE,PEX2,TUG1,CEP97,TMEM255A,RASGRF2,REV3L,FIGN,PRIMA1,ZFHX4,ALG9,ROBO2,RORB,RPE,SNX22,RYR3,SEC14L1,RASA3,HSPA4L,SGK1,ASAP3,CPEB3,CHD9,FNDC3A,BTBD3,MYH15,RCOR3,LMBRD1,SNRPN,MYO16,USP33,ZBTB43,RBM26,ZNF621,NKAIN2,ERBIN,STAC2,SULF2,NECAB1,JMJD6,PRRC2C,MTCL1,TAF9,ZFP90,ZEB1,TRIM2,FRYL,RNF216P1,FAM200B,SIRT1,ZMAT3,FAM124A,RIMBP2,KAT6B,TPM1,ELP5,TRPS1,SSBP2,ZKSCAN5,GORASP1,PLEKHH2,USP1,WIPF1,TRIM9,SPHK2,SPIRE1,ZFAND5,EMSY,SLC38A1,HPS4,PDSS2,FAM13C,ST7,RTN4,HNRNPA3,PHTF2,ADAMTSL3,TRAM2-AS1,RNF170,KLHDC1,SOCS4,FAM181A" MicroRNA hsa-miR-196b:mirSVR_lowEffct hsa-miR-196b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-79 5.76E-76 8.00E-79 7.37E-78 211 1236 "ACTN1,GALNT16,TMCC3,GALNT13,USP31,ADRB2,BEND6,HECW2,PCDH19,OSBPL1A,KIAA1324,AK2,ALCAM,ARHGAP20,PCDH10,FAM135A,DOC2A,AMPD2,AMPD3,AMPH,EP400,LCORL,LGR5,IGDCC4,CASK,CDK13,ZBTB10,CHRD,TMEM108,ATP1B3,TTLL9,BACH1,CFLAR,KSR1,GYG2,CACNB4,CAST,METTL6,CD86,DGKI,LRBA,SEPT7,ASIC3,B4GALT6,NDST3,PLAA,TPP1,ABCG2,C4orf33,SRP14-AS1,LETMD1,SLC4A8,AHCTF1,SMARCAL1,CS,RGS6,VAC14-AS1,FAM169A,PPP1R16B,APPL1,UBXN2A,GAPVD1,ZFYVE16,ELMSAN1,SLC29A4,DOCK2,DMTF1,DTNA,ECM2,E2F5,AASDH,EBF1,HIPK3,RASGRP1,TMTC1,APH1A,ASB3,EIF4G2,DCTN4,USPL1,EPB41,GPHN,RABEPK,SRRM1,ARMCX1,CHST15,ZNF589,POLR1B,SUCO,AGAP2,SYNCRIP,FOLR2,JKAMP,FAM49B,ATP6V1H,ZNF605,C15orf41,GATM,SULT1C4,PRRC2B,PRUNE2,CCDC184,CNTRL,RNFT2,RASSF8,HAS2,ATXN2L,AGBL5,ZNF491,ZDHHC15,CELF5,FAM95B1,C2orf72,NKD1,SLC35G1,KCNJ5,STXBP5,ZFYVE27,MAT2A,MBD1,AFDN,BLOC1S2,MXI1,MYO6,ZC3H12B,ALDH1L2,NME4,CNOT4,NOVA1,NPR2,IGSF11,OGG1,ETFRF1,PCDH8,PCSK5,PFKFB3,SERPINI1,CCSER2,PLCB2,MAPK9,MASP1,GDPD2,PIGG,BDNF-AS,PTK2,PTPRB,TUG1,ZDHHC14,RDX,RET,CARF,PCMTD2,MCMBP,KCNIP3,CLIP1,SEC14L1,FOXRED1,COPZ1,CPEB3,FNDC3A,ANKRD6,DHX30,TRIM67,MAST1,PDZRN3,MYO16,DOP1A,SOX11,MYCBP2,KDM4C,PEG10,TSPYL2,LMO3,LARP4,CEP68,ADHFE1,SYNE2,VPS13A,SYP,COBL,ANKRD28,MTCL1,CUX2,TPCN2,TRIM2,RPGRIP1L,SYNE1,DOCK9,TNS2,HIF3A,RNF216P1,DICER1,KHDC1,ZNF106,AKTIP,NPL,NR2C2,ZNF610,UGT8,WIPF1,RICTOR,XPO1,ZBTB14,ZNF24,KCNT2,CELF4,DHX33,PARP11,PHTF2,SOCS4,JPH3" MicroRNA hsa-miR-1258:mirSVR_lowEffct hsa-miR-1258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-79 8.15E-76 1.13E-78 1.04E-77 215 1285 "SYS1,NDRG2,GALNT13,BRAP,MTUS1,HFM1,CEP126,ABCD2,PCDH10,FAM135A,CCDC146,KCNAB2,APBB2,EPB41L5,UPRT,APOC2,BCAS1,CPNE5,TMEFF1,PLA2G4C,CADPS,TMEM108,SLC4A4,ATP2A2,MPDZ,BCHE,BMP7,MYRF,CAST,ISPD,ENTPD6,LRBA,LHX2,PLAA,CNN3,CNTN1,COL4A5,NECTIN3,SLC35F1,CREM,RBM39,RNF14,GDA,ABCG1,CSNK1E,KIAA0040,PNPLA8,GREB1,CCDC144A,LONRF1,LIN54,TMEM170A,HEPH,NR1D2,DTNA,MAMLD1,EDNRA,ANKRD46,SEMA3D,FAM13A,STARD3NL,GPHN,DENND4A,ZNF549,SPEG,RRAGB,KATNAL1,ABCA8,TMEM132C,GTF2IRD2,FOXO3,FLT1,ANKFY1,SYT3,ATP2C1,ZNF605,ST6GALNAC3,MPP6,MEGF10,GABRG2,ZNF559,GATM,ALDH1L1,GGT5,LYVE1,GLUL,CBX1,WDFY3-AS2,LPAR4,GPR34,TMEM121B,GRM2,BVES,AP4S1,HAS2,BACH2,ELOVL5,SYNPO,HSPA1L,ZIC5,IL6ST,ITPKB,LAMP2,SYTL4,NCOA7,MAT2A,CHIC1,LRP1B,MEF2C,KCTD6,MITF,COL28A1,MYO6,RTL5,CCDC13,NF1,NFE2L2,CNOT4,SLC11A2,SMIM11A,LOC100128398,OXTR,PCSK5,ZDHHC8,PIK3R1,XRN1,PLCL1,PURG,SCHIP1,ING3,PPM1B,NKAIN4,PRKACB,MAPK9,HYDIN,WBP1L,APTX,QRICH1,NCR3LG1,TMEM260,RIPOR1,ZSCAN2,QDPR,RASGRF1,RFX3,RIC8B,SETD5,EXD2,CCDC25,CCDC102B,ARMH4,MAP6D1,ATAT1,RTN1,SCN2B,CASC3,SH3GL3,FERMT1,SHC4,FHOD3,ST6GAL1,ABLIM3,PPP4R3A,FAM214B,KANSL3,SIRT2,SLC9A5,SLC12A2,SLC14A1,CABCOCO1,SNRPN,TMCC1,KDM4B,SOX3,SP4,UHRF1BP1L,ZBTB43,CLASP2,ZC4H2,NKAIN2,CEP68,ARHGEF9,NUDT10,SYPL1,TACR1,DNMBP,FAM208A,ALG1,ZEB1,TRIM2,GPRIN3,SIK3,TEK,FAM200B,AP4E1,TK2,ACTR6,RIMBP2,DOK6,ZNF346,AMACR,STXBP4,RICTOR,ZIC2,TMEM237,AMZ1,ZNF184,EML6,ZNF189,ZNF213,PDSS2,PHTF2,KLHDC1,NETO1,SENP7" MicroRNA hsa-miR-655:PITA hsa-miR-655:PITA_TOP PITA 2.84E-79 1.59E-75 2.20E-78 2.03E-77 169 789 "CCDC85A,ADD1,USP31,PWWP2A,AP2A1,PCDH19,HACE1,FAM135A,LRCH2,MAP4K3,APC,EPB41L5,GAS7,BCAS1,CASK,TMEFF1,NCOA1,EIF4G3,ATP2A2,SYNJ1,ARHGEF7,CALM1,RUNX1T1,CDH2,CCPG1,NUMBL,SOCS6,CHN2,QKI,HECTD1,MAP4K4,CNR1,ZNF521,SLC35F1,PHACTR3,SLITRK5,ERC2,PLCXD3,USP6NL,DOCK4,ZFYVE16,ZC3H11A,RHOBTB1,WDR20,DMD,CPEB2,SLC12A6,EBF1,SNX29,HIPK3,SEMA3D,YAF2,MBNL2,TENM1,PAN3,VPS13B,EPB41,EPB41L2,SRRM1,ETV1,EYA1,ACSL4,UBE2E3,MEX3B,PDLIM5,STAU2,MEGF10,CHL1,GABRB3,ARFIP1,GPR162,SESN1,AHDC1,GFRA2,PCDH17,SPIN1,STARD3,FERMT2,GPD2,GRM2,FAM19A2,KAT7,ZBTB49,ADAMTS6,ELOVL5,HMGCR,AGFG1,IPO5,STXBP5,KTN1,AQP11,MATN3,MBD1,CHIC1,LRP1B,MEIS1,MID1,MITF,MYO5A,NEFM,NF1,OPA1,CNTN3,PDE4B,GPR85,PIK3C2A,PIK3R1,STRN3,LRRN3,PPP3CA,CEP41,MAPK9,DIRAS2,SNRK,PTCH1,ELOVL2,PTPRG,PTX3,MARCH1,RBBP6,KHDRBS2,RDX,RGS4,SPIN3,RTN1,NCBP3,SATB1,FNIP1,CPEB3,FBXO11,WDR47,TRIM67,ZNF423,CDK19,RBM26,SSTR1,NKAIN2,KANK1,ZC3H4,PRRC2C,ANKRD28,ADGRL3,AGTPBP1,FBXW11,ATMIN,TCF4,SATB2,TRIM2,RPGRIP1L,DOCK9,DICER1,ZFPM2,CSMD1,TRPS1,VSNL1,WIPF1,XPO1,ZNF711,ZNF23,REEP1,ZFAND5,CADM2,NAV3,RGS7BP,FAM13C,HNRNPA3,JMJD1C,RNF146,ST8SIA2" MicroRNA hsa-miR-4260:mirSVR_lowEffct hsa-miR-4260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.98E-79 1.67E-75 2.31E-78 2.12E-77 228 1446 "ABR,ASIC1,ABHD6,TMEM132B,GALNT13,ADD2,DPY19L2P4,HECW2,CASKIN1,KCTD16,KIAA1324,CC2D2A,C1QTNF3,MARCH4,LTBP4,AMH,AMPH,OGT,LRCH2,SUGT1P4-STRA6LP-CCDC180,BCAS1,AQP6,PRX,MADD,SPTBN4,LINC00173,PDE8B,MARK4,CHID1,ATP6V1G2,TTLL9,ADAM15,BCHE,CFLAR,JAZF1,GYG2,GPC2,KALRN,SLC25A14,SPAG9,CBLN1,CBR1,CBS,CD38,ASIC3,QKI,HECTD1,COL9A1,LETMD1,SLC4A8,SEC31B,AKAP12,CRYBB1,PDE4DIP,PLXNA4,PPP1R16B,RIMS2,ARHGAP32,GAPVD1,SNPH,ARHGAP24,IP6K1,AIF1L,ARMCX4,PITPNC1,ELMSAN1,SNAP91,TMCC2,EXOG,RAB39B,HS3ST2,RPS6KL1,ECM2,DNM1L,AASDH,EDNRA,TMTC1,TMEM132E,AASS,CALCRL,GPHN,FCGRT,FKTN,PRMT5,FGF11,SPSB4,FGFR1,BAIAP2,MAD2L2,SUCO,SCARA3,EFCAB2,CGREF1,TPPP3,FYB1,GABRA3,FAM120B,ZNF274,GCK,TUBA8,GFRA2,TTBK1,TNRC6A,ADGRA3,STON1,PCLO,STMN2,GRB10,SPACA9,ADAMTS13,RNF165,AP4S1,SMAP1,ZNF546,IGF1,IL6ST,ZNF678,KIF5A,SFXN5,LIMS1,HECTD2,ZFYVE27,MAT2A,CHIC1,MEIS2,PTOV1,MYO7A,RTL5,NBL1,NF1,NOVA1,NPTX2,OGG1,DPY19L2P2,PFKFB3,PFKFB4,ZDHHC8,FAM216A,FXYD1,SLC25A23,PURG,PMP22,RETREG2,POLR2F,DIRAS2,CNNM2,BCAS3,GDPD2,CNTLN,TMEM260,ZSCAN2,ZNF793,GAL3ST4,ZMAT4,GTDC1,UBR7,RGS12,CCDC82,SETD5,TMLHE,ALG9,TCP11L1,KCNIP3,SEMA6D,SBF1,TNFRSF19,CASC3,SCAF8,SH3GL3,FHOD3,R3HDM2,ABLIM3,EPN2,PKNOX2,SEPHS1,SLC9A5,SLC11A1,KBTBD4,SMARCC2,MBD5,CABCOCO1,SNRPN,TMCC1,RBM34,PDZD2,ZHX3,ZSWIM8,NKAIN2,ELOVL4,SEPT8,ZC3H4,VPS13A,SLC37A2,FBXW11,MGRN1,TCF12,ARHGAP9,ITGB3BP,ERCC6L2,TPM2,ELP5,DCBLD1,TSN,SLC35A4,UBE3A,FLRT2,PLEKHH2,VSNL1,WIPF1,XRCC4,LGI4,ZIC1,ZNF32,ATP6V0E2,MKRN3,LYPD6,PCBP1-AS1,ZNF213,MEIS3,UPF3A,SLC30A3,GDPD5,PRDM8,KCNAB1,AMN1,HNRNPA3,GJC2,NETO1" MicroRNA hsa-miR-223:mirSVR_lowEffct hsa-miR-223:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.03E-79 1.69E-75 2.34E-78 2.15E-77 241 1608 "PWWP2A,BEND6,HACE1,OSBPL1A,OSBPL6,WDR35,TXNDC16,CEP126,FAM135A,GPRASP2,SUGT1P4-STRA6LP-CCDC180,CPNE5,AQP6,PPP4R4,TMEFF1,ZFYVE28,ARNTL,NCOA1,TMEM108,ATP1B3,DOCK11,TTLL9,BACH1,ADGRB3,SCAPER,WASF1,MYRF,KALRN,CAMK2G,CARS,CBR1,CD86,LRBA,CDH2,RAB28,QKI,CNTN1,AKAP5,AHCTF1,CRY2,ANKRD44,TRIM69,SNCAIP,SEC24C,CSNK1G3,PHACTR3,APPL1,RIMS2,PPP6R2,RUBCN,USP6NL,KIAA0408,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP24,HDAC4,ZFYVE16,LIN54,TMEM170A,SPOCK2,DBI,GIT2,YTHDC1,MFAP3L,KLHL3,POM121,PLPPR4,DMD,CPEB2,DOCK2,DMTF1,CASP8AP2,DTNA,EDIL3,TSPAN5,FCF1,MRO,KMT5B,AASS,EIF4G2,EIF1,GPHN,SRRM1,IGSF6,VPS26C,DNAJC27,F8,ABCA8,SH3YL1,SYNCRIP,RGPD5,FOXO3,FLT1,PSD2,EFCAB2,NBEA,STAMBP,CELF1,STAU2,NEURL4,ZMAT1,GABRB3,GABRG2,RAPGEF6,ALDH1L1,SULT1C4,MSTN,ARFIP1,TCERG1,COPS8,HPGDS,KDM2B,WDFY3-AS2,LILRB4,STON1,GPR37,PCLO,GRIA2,GSTM5,SOX21,GUCY1A1,HLF,HNF4G,KIAA1755,INPP1,ZNF667-AS1,MATN3,MEF2C,MID1,MMP16,NRBP2,MYO7A,MYT1,NF1,NFE2L2,NTRK3,DPY19L2P2,ETFRF1,PCDH9,PRTG,PDE4A,PDE4D,ZNF655,SNX10,JAKMIP1,PLXNB1,ANKRD16,MAPKAP1,LRP12,SCHIP1,MINDY2,PPM1B,PRKACB,CEP41,MAPK4,EPDR1,HYDIN,GDPD1,WBP1L,QRICH1,TMEM260,TMEM231,CEP97,FAM66C,ZDHHC14,ERI2,FIGN,RGS3,KLHL11,CCDC82,CARF,BAALC,TCP11L1,MEG3,SCN8A,TNFRSF19,SUPT20H,KIF21A,FAM102A,RADIL,KBTBD4,MBD5,KIF13A,SNRPN,TMCC1,MYO16,NMNAT2,UHRF1BP1L,SPTB,RBM26,CLASP2,ITPRID2,LARP4,SS18,STAU1,NEK4,SEPT8,CEP68,TTBK2,ADHFE1,STXBP1,SYN1,TACC1,MTCL1,CAMTA1,ADGRL3,TBL1X,SMG6,ATMIN,TCF4,ZFP90,CUX2,ZEB1,PMS2CL,ZNF106,SLC44A1,GALNT17,TIAM1,RGMB,TRPS1,PRR18,TSPAN11,GUSBP1,LGI4,MICU3,ZNF28,KCNT2,SPIRE1,FTSJ1,DHX33,PRDM8,TUBA1A,FZD3,HNRNPA3,CASC15,JMJD1C,MSRB3,ZDHHC20,IFT88" MicroRNA hsa-miR-4306:mirSVR_highEffct hsa-miR-4306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-79 1.72E-75 2.37E-78 2.18E-77 205 1174 "VWA5B2,KCNH8,CLK4,KDM5D,NDRG3,ADD2,PTCHD1,ZNF578,PCDH10,ZNF687,LRFN1,PHF12,VAT1L,PLA2G4C,ATP1A3,BACH1,ADGRB1,ADGRB2,CFLAR,THSD7A,KALRN,PTBP2,SLC25A14,VXN,LDB2,USP2,SYNGR3,DGKI,SRSF11,LHX2,CPNE6,PPT2,CNGA3,PCYT1B,ARMC8,AKAP6,SUMF2,COL9A3,SLC4A8,ZFP28,SLC35F1,PREPL,GDA,ABCG1,OSBPL3,CSNK1G3,PDE4DIP,UBXN2A,USP6NL,TCAF1,RIPOR2,DCAF8,TBC1D5,DGKB,PITPNC1,SPATA2,KLHL3,ZC3H11A,DMD,DNM1,DTNA,EBF1,SEZ6L2,FRY,APH1A,EBI3,ING4,TMEM35A,EIF1,DLC1,RACK1,ST3GAL6,POLK,EFCAB2,STAU2,GABRA3,GALC,DISC1,INPP5K,TUBGCP4,BRD8,TOX3,MSL3,STARD3,ZNF638,KDM2B,PRUNE2,CCDC184,PCLO,GRIA2,PLCD4,SERP2,KAT7,GSTT2,SOX21,FAM222A,RASSF8,UBE2QL1,PACSIN2,VSIG4,ACOT7,HMGCL,ZNF678,INPP5B,LRRTM1,KCND1,KCNJ16,KCNN2,KCNN3,CYP27C1,PIK3AP1,MAP2,MAP4,MAT2A,MEIS1,SRSF12,MSI1,MYO9A,RTL5,NINJ2,GLIPR1L2,PCDH9,CCSER2,PRIMPOL,PRKACB,WDR25,CNTLN,PTPN13,PTPRE,QDPR,FAM66C,FAM184A,ZCWPW1,RDX,TRIM68,DPF2,PRRT2,MORC4,SLC25A36,SETD5,KLHDC8A,CARF,LRRK2,ABCA11P,ATAT1,ZNF568,TRAPPC13,FAM192A,ATXN2,LRFN5,SH3BGR,MYO18A,BTBD3,SLC8A1,CDK5RAP3,CPEB4,ZKSCAN3,SMARCC2,SNAP25,KDM4B,HECW1,SPTB,DDN,CLASP2,SSTR2,ZC4H2,ELOVL4,PHLDB1,ZC3H4,SYN1,TMEM150C,ASTN2,TPCN2,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,CDH22,GALNT17,MTMR14,NPL,CHST5,ELP5,TSN,TSC1,SSBP2,TTC3,RPL7L1,WIPF1,NPDC1,CELF4,LAMP5,SLC30A3,HPS4,SLC17A7,PARP11,KAT6A,KLHDC1,IFT88,NETO1" MicroRNA hsa-miR-769-5p:mirSVR_lowEffct hsa-miR-769-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.53E-79 1.97E-75 2.72E-78 2.50E-77 227 1435 "ASIC1,ABHD6,NDRG3,KLHL32,ADCY6,ADD2,AP2A2,HACE1,OSBPL1A,CC2D2A,SEMA6A,CEP126,CARNS1,ZFAT,PI16,SUGT1P4-STRA6LP-CCDC180,PHYHD1,IGDCC4,MARK4,RASL11B,DPY19L3,BAIAP3,CA12,HAP1,VXN,SLC16A4,ARHGEF1,CD38,ENTPD6,LRBA,CDO1,CCPG1,NUMBL,PLAA,TPP1,SLC4A8,ABI3BP,AHCTF1,TOGARAM2,SEC24C,PNPLA8,DCAF4,RUBCN,KIAA0408,GAPVD1,ZFYVE16,TBC1D5,DGKG,DAPK1,KIAA0753,DDX46,SV2B,TMCC2,DPP6,COPS4,ING4,VPS13B,GPHN,IGSF6,ZNF549,SPEG,MRPL37,EZH1,F5,ABCA8,FAM198B,ZNF461,CORO2B,FGF11,SPSB4,PRKAG2,POLK,SUCO,SCARA3,SEC23B,PSD2,AKAP3,ERGIC3,KHDRBS3,AP4B1,TVP23A,NEURL4,GALC,IP6K3,GHDC,GPR162,GLI2,GLYR1,KCNMB4,GPD2,PRUNE2,SPACA9,PRDM5,KAT7,FAM107A,HMGCR,IFI16,DISP2,METTL21A,KCNK3,CREG2,KIF5A,STMN1,SFXN5,ZFYVE27,AQP11,ADAM11,CHIC1,MGAT3,SCAMP5,PPM1L,MSI1,MYO7A,NEXMIF,PDE1B,ZDHHC8,NLGN3,SEMA5B,TMIE,FAM218A,CCSER2,MAPKAP1,SCHIP1,ING3,EPB41L4B,FSD1,POU6F1,PRKAB2,MAPK9,MASP1,ELOVL2,ZIK1,PTPRH,PEX2,ZSCAN2,NKAIN1,MARCH1,RASGRF1,RASGRF2,ZDHHC14,GTDC1,SLC25A36,ZNF532,EPHA10,FBXW7,ADAL,STK32B,EMID1,LRRK2,HSD11B1L,ZNF354C,FAM192A,AP1AR,MAPK12,ATXN2,CASC3,SCAF8,HKDC1,ST6GAL1,WDR37,EPN2,PKNOX2,ARHGEF40,SLC11A1,SLC12A4,SMARCA4,SMARCC2,ANKRD36,ZBTB43,MCF2L2,RBM26,CLASP2,CLSTN2,ITPRID2,ZC4H2,SS18,DIP2A,SEPT3,PRRC2C,ARHGEF9,VPS13A,ADAMTS17,DNAJC9,ARC,SYP,MTCL1,MLST8,ADGRL3,FBXW11,TBL1X,CUX2,TCF12,CLASP1,SZT2,DOCK9,PCDHB4,AP4E1,GALNT17,TIAM1,TMPO,RASD2,NPL,TPM2,ZNF346,ELP5,TRPS1,TSN,UBTF,LINC00689,LGI4,ZNF28,ZBTB38,POLR3H,FSTL5,DPYSL5,PCBP1-AS1,EMSY,LINC02210,AMN1,DOCK8,UBE3B,CASC15,MSRB3,IFT88,RNF146,AP3B2,ST8SIA2" MicroRNA hsa-miR-221:mirSVR_highEffct hsa-miR-221:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.71E-79 2.08E-75 2.86E-78 2.63E-77 192 1030 "RALGAPA1,ACADM,CLK4,AXIN2,ESYT2,LRFN2,RTL9,WDR35,SPARCL1,PCDH10,PITPNM2,CCDC146,APAF1,ASPA,NUMB,ATP1B3,DPY19L3,LINC00847,BCHE,DST,CA8,CACNB4,CALB1,PTBP2,LDB2,KRIT1,DGKI,MAGI1,CLGN,SRSF11,NDST3,C4orf33,QKI,CNR1,ARMC8,AKAP5,SLC4A8,CREM,RGS6,SEC24C,CST3,KIAA0040,USP6NL,KATNAL2,GAPVD1,TCAF1,ZFYVE16,KIAA0586,KCTD8,SPATA2,MYEF2,SNAP91,SPOCK3,NR1D2,PDCD6IP,ARRDC4,ABCC5,EBF1,FCF1,EMX2,ABCA8,SEC24B,OLFM1,POLK,NELFCD,SMC2,GABRG2,GAD1,ZNF234,KIAA1841,NEU3,SULT1C4,GDF9,GGTA1P,PPARGC1A,BRD8,GLI2,LUZP2,LOXL3,FERMT2,GPD2,ATP2B1-AS1,ZBTB49,ADAMTS6,GUCY1B1,MAP4K5,DDX19B,MIER3,AGBL5,HNMT,ZNF181,LRRCC1,INSM1,KIT,STMN1,HECTD2,NCOA7,MARK1,MAT2A,MEIS1,MEIS2,ADAM22,LYRM9,NEFH,NEK1,NF1,NOVA1,CLDN11,GLIPR1L2,CDK18,PDE4B,PFKFB2,RETREG1,PDZRN4,MAGEL2,EPB41L4B,PPM1B,PPP2R5E,EPDR1,MAPK10,VPS13C,ANKHD1,PTPN13,EML5,ZNF615,CEP97,KHDRBS2,RDX,ERI2,RFX3,SLC25A36,CARF,RORB,PCMTD2,MRAP2,BAALC,SPIN3,ZFP30,KIF16B,CPEB3,FBXO11,FNDC3A,SYBU,WDR37,PPP4R3A,WDR47,CCDC88A,TET1,CPEB4,SNCA,TMCC1,HECW1,ZC3H13,SPART,POGZ,ZNF302,NXT2,ADHFE1,CAMTA1,EXOC7,FAM208A,AGTPBP1,TBCEL,TCEA1,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,ZFPM2,ITGB3BP,ERCC6L2,TMPO,RIMBP2,TP53BP2,TRPS1,PLEKHH2,TRIM9,EML6,CADM2,RNF103,TUBA1A,SEMA3B,NAV3,PLSCR4,MSRB3,NHSL1,AP3B2" MicroRNA hsa-miR-1182:mirSVR_lowEffct hsa-miR-1182:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.85E-79 2.15E-75 2.96E-78 2.72E-77 238 1572 "VWA5B2,ASPHD1,SYN3,SYS1,GALNT13,RNF157,PWWP2A,PTCHD1,AP2A2,MTUS1,PCDH19,ADGRF5,SPARCL1,PCDH10,AMPD3,PKP4,PARG,APAF1,BCAS1,SFMBT2,ARHGDIA,ARRB2,MARK4,SLC2A11,ADGRB2,RGS11,NRP2,CFLAR,SYNJ2,CASTOR3,WASF1,CALM1,HAP1,CAPN3,SPAG9,KYAT1,LDB2,METTL6,USP6,USP2,SYNGR3,ARHGEF2,SEPT7,SRSF11,CNOT8,NDST3,IGLON5,SMARCAL1,RNF14,ANKRD44,GDA,CSF1,CNTNAP2,DCAF4,GPRASP1,GAPVD1,TCAF1,RIPOR2,TBC1D5,IST1,GIT2,ELMSAN1,MFAP3L,RUSC2,POM121,HS3ST2,DTNA,GOLT1B,GOLGA7,CERCAM,EPB41L2,COQ7,MRPL37,VPS26C,HSPA12B,ABCA8,NSRP1,PTK2B,POLR1B,FGF11,SPSB4,PRKAG2,IP6K2,AGAP3,WDR83,SPECC1,FAM49B,USP21,CGREF1,GABRB3,B4GALNT1,DISC1,ALDH1L1,LYVE1,DBF4,GLYR1,GPD1,CCDC184,MCHR1,TMEM121B,DIDO1,CIT,COQ10A,ZBTB49,BVES,AP4S1,ADAMTS6,UBE2QL1,PADI2,SYNPO,SHISA6,NKD1,ZIC5,SCIN,JAK2,KCNJ16,KIF2A,LINC00634,IPO5,CYP27C1,KTN1,SFXN5,ZFYVE27,MAP4,MEF2C,PTOV1,MYO6,MYO7A,CCDC13,NF1,SETD4,TBC1D25,DPY19L2P2,PDE1C,PDE4D,PDPK1,PFKFB3,CCSER2,TMEM38A,PLCB2,SDK2,EPB41L4B,PILRA,PPARA,MINDY2,KANSL1,PRKAB2,RASGEF1B,MAPK4,MAPK10,GRAMD1C,HYDIN,BCAS3,VPS13C,TMEM260,PTPRE,TMEM231,FAM66C,CRTAC1,ZDHHC4,RGS12,RIC8B,LGI2,ALG9,CARF,CYB561D1,ROBO2,RPE,SNX22,EPHA10,MAP6D1,CCDC112,S100B,MAPK12,SCP2,EPN2,FAM214B,INAVA,KDM4B,PDZD2,NMNAT2,KDM4C,ERC1,PEG10,ZC3H13,SST,SSPO,ZSCAN29,STAC2,NSFL1C,RHBDL3,TMEM150C,SYN2,SYP,ANKRD28,TACC1,CAMTA1,ATMIN,ZFP90,TCF12,NAT16,SLC19A3,OBSL1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ERCC6L2,NPL,TPM2,C9orf85,METTL3,SMUG1,STXBP4,SGK3,UBTF,ZIC1,KCNT2,ZNF74,TMEM237,POLR3H,TMEM198,DNALI1,SLC38A1,PRDM10,RNF103,SEMA3B,GAL3ST3,PDSS2,UBE3B,CASC15,RNF170,ADAMTS10" MicroRNA hsa-miR-101-3p.2:TargetScan hsa-miR-101-3p.2 TargetScan 4.34E-79 2.43E-75 3.33E-78 3.07E-77 170 801 "NDRG3,ELFN2,CCDC85A,AXIN2,OSBPL1A,ALCAM,PCDH10,BEGAIN,DPP10,LRCH2,PPFIA4,APC,MARCH3,RASL11B,ATP2B2,BACH1,BMPR1B,DST,FUBP1,MTMR2,LDLRAD4,RUNX1T1,CBFA2T2,DGKI,CDH2,KCNAB3,MAGI1,NOG,NRXN3,QKI,HAPLN1,PPP1R16B,PYGO1,HDAC9,JAKMIP2,MYEF2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,ABCC5,EBF1,HIPK3,FEM1B,FRY,PHF20L1,MBNL2,PLXNC1,EIF4G2,EIF5,RGS17,ELN,MTSS1L,ENPP6,ERBB4,ETV1,ACSL4,DLC1,MED12L,MEX3B,PSD2,HVCN1,ATP2C1,PPARGC1A,GLI2,GPR37,GRIA2,DIDO1,KAT7,FAM222A,PACSIN2,BACH2,ELOVL5,HMGCR,AGFG1,JAK2,CDH20,KCNN3,KIF2A,KIT,CYP27C1,LIFR,PAXBP1,MARK1,MBNL1,MEIS2,KITLG,MITF,MSI1,MYCN,NCAM2,NOVA1,NPTX1,CHAMP1,CNTN3,PCSK5,PDE4A,PDE4D,GPR85,PIK3C2A,GPSM2,PLCL1,PCDH18,LRP12,PPARA,PPP2R5E,PPP3CA,PTCH1,PTPN13,PTPRG,PTX3,FAT4,RASGRF1,KHDRBS2,REV3L,GTDC1,FIGN,RFX3,PBRM1,ROBO2,FBXW7,RYR3,SALL1,SATB1,SCN8A,FNDC3A,R3HDM2,BTBD3,EPN2,ATF7IP,CXXC4,LIMCH1,MBD5,FAM126B,KDM3A,ARHGAP26,NFASC,LMO3,RGL1,PRRC2C,ADAMTS17,PLCB1,ANKRD28,ANKRD12,MCF2L,FBXW11,MGRN1,DMXL2,NSD1,PUM2,FRYL,DICER1,ITGB3BP,NACC2,BHLHB9,KAT6B,RASD2,FLRT2,KCNK12,NDRG4,NAV3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,NETO2,GAN,PRRT4" MicroRNA hsa-miR-1273d:mirSVR_lowEffct hsa-miR-1273d:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.05E-79 2.83E-75 3.87E-78 3.56E-77 234 1524 "RALGAPA1,SYS1,TMEM132B,CCDC85A,ESYT2,HECW2,AGT,RTL9,KIAA1324,PCDH10,AMT,OGT,DPP10,PKP4,APAF1,EPB41L5,USP37,PPP4R4,ZBTB10,NCOA1,DPY19L3,SEC11C,DNAJC27-AS1,SCAPER,CALB2,CALM1,SPAG9,PRC1,LRRFIP1,LARGE1,SOCS6,ARHGAP22,FAM19A5,ARHGEF6,IQCK,PCYT1B,TBPL1,MYRIP,RBM39,CRMP1,GDA,CLIP3,TRIM69,RGS6,CSNK1G3,SLITRK5,APPL1,GAPVD1,IP6K1,ARMCX4,SPATA2,HEPH,ELMO1,POM121,SNAP91,SPOCK3,GRIN3A,DMD,NR1D2,ACOT8,DRP2,ARRDC4,EBF1,EDNRA,YAF2,PHF20L1,EIF5,IRAK4,USPL1,VPS13B,STX2,ZNF549,ETV1,ABCA8,DLC1,CEP78,FDFT1,BAIAP2,PRKAG2,MEX3B,SYNCRIP,EVL,FLT1,FOLH1,DCTN2,PDLIM5,CSPG5,TVP23A,GABRG2,DENND2A,GALC,ZNF234,ERAP1,DISC1,INPP5K,AHDC1,MMADHC,PPARGC1A,SPIN1,GLYR1,TOX3,MSL3,LNX1,TDRKH,PCLO,ZNF496,BTN2A1,RNF165,KAT7,ZBTB49,ZHX1,PACSIN2,FRMD3,HLF,GABARAPL2,SYNPO,AGBL5,HSF2,CELF5,MSL1,IPO5,CYP27C1,STMN1,NCOA7,PACRG,GPR155,MAP2,AFDN,XRRA1,MSR1,ZC3H12B,NINJ2,NTRK2,OGG1,OPA1,PCSK1,PCSK5,CDK18,PDE4D,NALCN,LRP12,SH3KBP1,IRX1,GRAMD1C,GDPD2,PIGG,PTK2,TMEM260,PTPRE,PEX2,RIPOR1,ZSCAN2,TUG1,RASGRF1,RBBP6,RDX,ERI2,RFX3,EXD2,ARMC5,CCDC25,YY1AP1,CCDC102B,SNX22,SPIN3,ATP8B4,MEG3,NCBP3,DGLUCY,ATXN7,SCN7A,TNFRSF19,MRAS,TRA2B,FERMT1,PEX26,ZNF430,SLC9A5,CPEB4,ZKSCAN3,LIMCH1,MAPKBP1,KIF13A,SNRPN,DOP1A,PDZD2,KDM3A,ZC3H13,LMO3,POGZ,LARP4,ZSCAN29,SYN2,SYP,SYPL1,ANKRD28,TACR1,TAF9,ADGRL3,TBCEL,ZFP90,PCDHB10,FRYL,ITGB3BP,AP4E1,RIMBP2,METTL3,PPIL6,UBE3A,ZNF709,BCL2L13,TOM1L2,CCDC14,RICTOR,XPO1,PCDH20,ZFP37,MKRN3,LYPD6,ZNF154,REEP1,EML6,ANKS1B,ZFAND5,EMSY,CIAPIN1,SIGLEC10,KCNAB1,WNK3,RGS7BP,UBE3B,HNRNPA3,ADAMTSL3,SPATA13" MicroRNA hsa-miR-625:mirSVR_lowEffct hsa-miR-625:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.06E-79 2.83E-75 3.87E-78 3.57E-77 236 1549 "CLK4,EMILIN3,SYS1,GALNT16,RNF157,OLMALINC,C1QTNF3,CARNS1,UNC79,BEGAIN,AMT,DPP10,CCDC146,CPNE5,LINC00173,MARCH3,NUMB,N4BP2L1,ATP6V1G2,HCN2,PROM1,SYNJ2,ARHGEF7,CACNA1I,CALM1,PTBP2,HIP1R,CBLN1,METTL6,USP2,SYNGR3,TAOK2,EPS15L1,CLTC,ABCG2,MAP4K4,HOMER3,IGLON5,AKAP5,ZNF385A,CPS1,SEC31B,AKAP12,GDA,SEC24C,IPCEF1,PDE4DIP,PITPNM3,PHF14,PLCXD3,HDAC9,MYADM,SNPH,SPOCK2,GIT2,SPATA2,DCTN1,KLHL3,POM121,SPOCK3,SGSM2,DPP6,DPYSL2,ACOT8,DRP2,MAMLD1,ABCC5,PHC2,CNNM1,SEMA3D,TMTC1,PHF20L1,SUGP2,EGFR,MBNL2,EGR3,AASS,GOLGA7,EIF1,COQ7,EPHB1,DENND4A,SPEG,MRPL37,MRVI1,CHST15,FKTN,FDFT1,FGF11,FGF13,AMOTL2,IP6K2,FLYWCH1,SPECC1,FAM49B,ZNF605,ERGIC3,DOT1L,GALNT15,GABRB3,TMEM8B,CPLX2,CYP46A1,ADAM28,GGT7,GLYR1,TNRC6A,GLUL,DCLK2,RNF165,MUM1,UBE2QL1,NEGR1,IGF1,TJAP1,ZNF678,NME9,SLC35G1,KTN1,HECTD2,MAPT,KCTD6,SCAMP5,POC1B,AFDN,PTOV1,MYO6,MYO9A,NF1,NFYA,NINJ2,NME4,VWA2,IGSF11,PAX6,CDK18,PRTG,PDE4A,PDE4D,PDPK1,PFKFB3,ZDHHC8,NLE1,PLIN1,STRN3,MBOAT7,POLG,PPP1R1A,KANSL1,RASGEF1B,MAPK4,DCHS2,SAMD9,BCAS3,WBP1L,DEF8,ACSS3,IQSEC3,RDX,CCDC82,FBXW7,SEMA6D,CASC3,FAM102A,FERMT1,KIF16B,ASAP3,SHMT2,FBXO11,FHOD3,ANKRD6,EPN2,SLC6A11,SEPHS1,SLC8A1,SLC11A1,SLC12A4,CPEB4,SMARCC2,CDK5RAP2,RCOR3,INAVA,SNRPN,FAM219A,ZSWIM8,MYCBP2,KDM4C,SPTB,IQSEC2,SSPO,CEP68,STX1A,NECAB1,RHBDL3,PLCB1,SYN1,ANKRD28,TBCEL,FBXW11,WSCD1,PCDHB6,NSD1,PCDHA5,FRYL,CYB561A3,GPR161,ZMAT3,AKTIP,THRA,TIAM1,MTMR14,BHLHB9,NR2E1,ZNF346,STXBP4,TRPS1,TSC1,PRR18,GORASP1,MGAT5B,VLDLR,TSPAN11,TRIM9,ZNF70,ZNF213,MEIS3,PRTFDC1,DNALI1,PRDM8,GAL3ST3,MPPE1,PDSS2,CASC15,MSRB3,TTC7A,JPH3" MicroRNA hsa-miR-345:mirSVR_lowEffct hsa-miR-345:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.95E-79 3.33E-75 4.55E-78 4.19E-77 242 1626 "NCKAP5,SYS1,ADCY6,ADD1,OLMALINC,OSBPL1A,KIAA1324,WDR35,AK2,ALCAM,FAM135A,ZFAT,SUGT1P4-STRA6LP-CCDC180,MADD,TMEM108,CHID1,SLC2A11,ADAM15,BACH1,BBS2,RGS9,NRP2,CFLAR,DST,CASTOR3,MTMR3,GYG2,GPC2,LDLRAD4,CALB1,KALRN,ISPD,SPAG9,CBFA2T2,AP4M1,LRRFIP1,MAGI1,UBE2L6,TAOK2,C7orf61,ABCG2,CNGA3,AKAP7,COL4A5,LETMD1,HINFP,TRIM69,IPCEF1,PDE4DIP,FAM169A,CTH,RIMS2,DOCK4,ARHGAP32,TBC1D5,DAPK1,YTHDC1,B3GAT3,TMEM130,RHOBTB1,SPOCK3,FAM107B,ZNF582-AS1,RAB39B,NYAP1,USP3,CPEB2,SLC25A18,FARSB,ABCC5,EDNRA,SEMA3D,PHF20L1,RASA4,AASS,IRAK4,EXTL2,FAM198B,PTK2B,STRADA,GTF2IRD2,FGF1,FGF11,TMEM164,SUCO,SMC2,ERGIC3,SARAF,TVP23A,OGA,MEGF10,GABRG2,FAM120B,IP6K3,GATM,GCNT2,SRCAP,GPR162,NFU1,GGT7,ZNF276,STARD3,KDM2B,ADGRA3,TDRKH,GPR12,STON1,GRIA2,PLCD4,GRM8,BTN2A1,ZBTB49,BVES,RNFT2,ELOVL5,GABARAPL2,IRF8,ZNF546,RBPJ,TJAP1,SCIN,IL6ST,KCNJ5,KCNN1,LAMP2,STMN1,SYTL4,MAN2A2,MARK1,PPM1L,MMP16,LYRM9,MYO7A,ZNF862,HNRNPM,NF1,ALDH1L2,DNHD1,SLC11A2,PCSK1,PDE1C,PDE4D,OLA1,CCSER2,GPSM2,PLCL1,LRP12,SDK2,ING3,DRAM2,PPM1B,PPP5C,PRKCB,EPDR1,MAPK9,SAMD9,TMEM104,CNTLN,PTCH1,ZSCAN32,PTPRB,PTPRD,PTPRN,PTPRO,RIPOR1,PPP2R3C,QDPR,CEP97,ACSS3,ZNF793,SH3TC2,NWD1,RASGRF2,RGS3,SLC25A36,ZNF532,TMLHE,EXD2,CARF,ROBO2,RPL15,MCMBP,ATP8B4,STK32B,CCDC112,TRAPPC13,S100B,PRCD,FNIP1,COPZ1,CPEB3,NUBPL,ABLIM3,FAM214B,SLC8A1,ARHGEF40,SIRT2,SLC12A4,ZNF667,OGDHL,ANKRD36,INAVA,USP33,DOP1A,TRERF1,BDP1,DOK5,TROVE2,ELOVL4,KANK1,SULF2,PJA1,TAL1,SMG6,TCF4,CUX2,NAT16,SLC19A3,TNS2,ENHO,TIAM1,BHLHB9,ELP5,TRO,TRPS1,TSC1,TTC3,CLHC1,SLC47A2,ZNF142,POLR3H,MEIS3,UPF3A,SLC30A3,PRDM8,ADAMTS9,KAT6A,FBXO36,CASC15,JMJD1C,TIGD6,FRMD6" MicroRNA hsa-miR-363*:mirSVR_lowEffct hsa-miR-363*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.98E-79 3.91E-75 5.33E-78 4.91E-77 243 1640 "KCNH8,ASIC1,SYS1,ACTN1,GALNT16,ADD1,UNC5A,FAHD2CP,SPOP,SYT13,AMPH,SUGT1P4-STRA6LP-CCDC180,TNRC6C,LGR5,SEMA4G,PRX,LINC00173,MARCH3,NUMB,ATP2B2,CARMIL3,BBS2,RGS9,KSR1,GPC2,P2RX6,CD86,ARHGEF1,ENTPD2,ENTPD6,LOC730101,SRSF11,NDST3,HECTD1,MAP4K4,COL11A2,SLC4A8,IGDCC3,SEC31B,AKAP12,CRY2,GDA,RGS6,CSNK1E,RIMS4,CNTNAP2,SLITRK5,ZSCAN23,CYBB,KIAA0408,GAPVD1,HDAC4,TMEM170A,DAPK1,SCRN1,PITPNC1,MFAP3L,RUSC2,SGSM2,GRIN3A,DPP6,DRP2,DTNB,CNNM1,HEYL,CELSR3,APH1A,ASB3,EIF5,PLEKHA1,ELN,DCTN4,COQ7,STX2,MRPL10,VPS26C,NRN1,REEP2,FKTN,KAT8,POLR1B,FGF11,FGF13,HPCAL4,FLNC,SLC37A3,SYT3,NBEA,CAMKK2,KHDRBS3,BRSK1,GABBR1,B4GALNT1,ZNF234,IQGAP2,AHDC1,GHR,MALT1,GLI2,MSL3,GNG4,GPD1,PRUNE2,PLCD4,CACFD1,GRIN2D,BTN2A1,ZBTB49,FAM107A,UBE2QL1,MAN1B1,ATXN2L,AGBL5,HSPA1L,SMAP1,FAM95B1,RBPJ,DISP2,INSM1,LRRTM1,KCNJ5,A1BG-AS1,STXBP5,KTN1,LIMS1,MAP4,MBD1,PPM1L,MN1,MOV10,GIT1,MSR1,MYO7A,RTL5,MYT1,NINJ2,NME4,DNHD1,NUCB2,OGG1,PDE4A,PDE1B,GNG2,PFKFB3,PKM,FAM216A,PLCB2,PLCD1,SLC25A23,PURG,PNMA3,MAPKAP1,LRP12,RETREG2,POLR2F,RANBP3L,EPDR1,PSD,TMEM104,WDR25,CNTLN,ANKHD1,PTPRB,PTPRE,NKAIN1,PID1,GAL3ST4,DPF2,PRRT2,ERI2,GTDC1,RGS12,PRIMA1,KCTD17,RIC8B,ROBO2,ELP2,ABCA11P,ZNF331,GALNT10,COPZ1,SEC31A,DZIP1,PPP4R3A,PKNOX2,ARHGEF40,TRIM67,ATF7IP,CXXC4,SMARCD3,SNAP25,MBD5,SNRPN,USP33,SOX3,DOK5,IQSEC2,ZBTB43,DDN,NFASC,CLSTN2,SSTR1,NEK4,DIP2A,KANK1,RHBDL3,ADAMTS17,SYP,COBL,SLC37A2,SYT5,MGRN1,SZT2,PCDHGA11,NAT16,PCDHB9,NSD1,TNS2,DICER1,DICER1-AS1,C18orf54,ACTR6,CABIN1,DCBLD1,KCNE5,SSBP2,SLC35A4,MGAT5B,LMF1,WNT7A,ELFN1,SPHK2,ANKS1B,GDPD5,STOX2,SEMA3B,SLC17A7,FIP1L1,PCBP4,FAM13C,DOCK8,ST7,TTC7A" MicroRNA hsa-miR-3159:mirSVR_highEffct hsa-miR-3159:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.41E-79 4.15E-75 5.65E-78 5.20E-77 194 1056 "RALGAPA1,KCNH8,KDM5D,NDRG3,ADD1,PLEKHH1,OLMALINC,TXNDC16,OGT,LRCH2,NUMB,SLC4A4,ATP6V1G2,BMPR1B,FUBP1,IL33,LURAP1,KALRN,PTBP2,METTL6,SLC16A4,LRRFIP1,SRSF11,SOCS6,PLAA,MAP4K4,LY86,CNTN1,AKAP6,RCHY1,RTTN,SLC35F1,ENTPD4,CRMP1,ANKRD44,SEC24C,VCAN,PUM1,ZSCAN23,ARHGAP32,ZFYVE16,TBC1D5,MATR3,DAPK1,ELMO1,ALKBH8,SACS,EXOG,DPYSL2,FAM78B,DNM1L,E2F5,EDNRB,ANKRD46,SEMA3D,TMTC1,FSD1L,FAM13A,KMT5B,ELN,PAN3,EIF1,VPS13B,NCALD,CEP85L,MRPL37,ETV1,F5,F8,ZNF461,ZNF585B,FCGR1A,CEP78,KAT8,MED12L,FGF14,POLK,SUCO,TMEM107,SMC2,ATP2C1,STAU2,FYB1,GABRG2,DISC1,KIAA1841,SULT1C4,PPARGC1A,HPGDS,GNAL,GPR12,LPAR4,PSIP1,MAP4K5,FRMD3,NCKAP1L,HLF,TCEAL6,IFI16,DISP2,SCIN,ZNF678,KIF2A,IPO5,STXBP5,KTN1,GPR155,MAP4,MARK1,MEF2C,MEIS1,SRSF12,ZNF680,MYCN,MYO9A,NEK1,NNAT,SLC11A2,SETD4,CHAMP1,GLIPR1L2,ETFRF1,ENPP2,GPR85,SNX10,TMEM38A,PCDH18,MTRF1L,PURG,TRHDE,ING3,FA2H,MAPK9,PTPRD,TMEM255A,ZMAT4,RGS12,ZFHX4,CCDC82,TMLHE,CARF,RPL15,BAALC,RYR3,SATB1,FNIP1,TNFRSF19,SEC31A,SLC8A1,BTBD7,MYO16,SP4,MYCBP2,PBLD,CLASP2,NXT2,APOM,DIP2A,KLHL7,VPS13A,TAF9,SATB2,CUX2,TCF12,PCDHGB7,PCDHB6,PCDHB3,PUM2,USP32P1,FRYL,DICER1,ZFPM2,LRRC8A,NPL,TPM2,ANKRD20A2,EIF4ENIF1,UBE3A,ZNF708,MICU3,TRIM9,ATP6V0E2,CRB2,ZNF177,FSTL5,DHX33,MPPE1,RGS7BP,AMN1,TRAM2-AS1,RNF170,FRMD6,IFT88,NETO1" MicroRNA hsa-miR-143:mirSVR_highEffct hsa-miR-143:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.07E-78 6.00E-75 8.17E-78 7.52E-77 207 1205 "KCNH8,GALNT16,AP2A2,KLHL13,WDR35,ZNF578,FGD2,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,RGS20,NUMB,ZNF583,SLC2A11,ATP6V0A1,AZGP1,SEC11C,SCAPER,GYG2,CACNA1A,THSD7A,CALM1,PTBP2,CAST,SPAG9,CBFA2T2,LRBA,DCLK1,TIGD7,SRSF11,RAB28,PPT2,QKI,AKAP6,COL4A5,COL11A2,SLC4A8,FAM171B,SEC31B,PREPL,RBM39,RNF14,GDA,OSBPL3,CSNK1G3,VAC14-AS1,CTH,CYBB,DOCK4,HDAC9,ARHGAP32,KATNAL2,DCAF8,ZFYVE16,EARS2,DAPK1,ELMO1,TMEM130,DDX46,DOCK2,DMTF1,ARRDC4,DTNB,ANKRD46,COPS4,PAN3,SRRM1,CDKL3,CLVS1,FAM198B,DLC1,FDFT1,SLC9B2,FGF1,UBE2E3,SYT3,SMC2,TPK1,STAU2,GABBR1,GALC,DISC1,GATM,GHR,PPARGC1A,COPS8,ZNF638,PRUNE2,PCLO,ZNF496,KAT7,AP4S1,ZHX1,HMGCL,IL6ST,ZNF678,JAK2,KCND1,KCND2,STXBP5,NCOA7,MYO5A,MYO6,MYO9A,NDP,NEK1,CNOT4,NTRK2,OPA1,GLIPR1L2,PDE1C,OLA1,GPSM2,PLIN1,STRN3,LRP12,RASGEF1B,MAPK7,MAPK9,CNTLN,BDNF-AS,TMEM260,PTPRB,PTPRD,PEX2,CEP97,RAD51D,SH3TC2,RASGRF2,RDX,KCTD17,SETD5,TMLHE,CARF,ROBO1,ARMH4,ADAL,STK32B,PTGR2,ZNF354C,FAM192A,LRFN5,FOXRED1,SCAF8,ZFP30,FERMT1,ASAP3,ANKRD6,FAM81A,SLC12A4,ELMO2,TET1,EPC1,CDK5RAP2,LIMCH1,SNRPN,KDM4C,ZBTB43,ATP10B,TROVE2,STXBP1,KLHL7,NUDT10,PLCB1,SYN2,ANKRD28,C12orf76,ANKRD12,TRIM2,PCDHB10,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TIAM1,MTMR14,RELL2,ERCC6L2,TMPO,NPL,HSPBP1,ZNF610,FAM155A,TBC1D15,KLC2,ZIC1,ZNF28,TRIM9,MKRN3,FSTL5,FTSJ1,MEIS3,UPF3A,CADM2,LINC02210,HPS4,URM1,SLC17A7,PDSS2,NLRP3,RNF170,NETO2" MicroRNA hsa-miR-654-5p:mirSVR_lowEffct hsa-miR-654-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-78 6.07E-75 8.25E-78 7.59E-77 241 1618 "ASPHD1,FMNL2,GALNT16,TMCC3,ADD1,BRAP,ADORA2A,AP2A2,SPOP,CEP126,SYT13,AMPD2,FGD2,CCDC146,LCORL,KCNAB2,PHYHD1,TNRC6C,PPFIA3,USP37,PRX,MADD,SPTBN4,ZFYVE28,ARHGDIA,CCDC74A,NUMB,DYNLL1,ATP6V0A1,RIPK1,RGS9,BCL7A,CFLAR,KSR1,MYRF,CFAP410,CACNA1A,DDR1,KALRN,HAP1,RUNX1T1,CBS,USP2,ENTPD6,KCNAB3,NUMBL,CACNA2D2,FOXN3,ASIC3,TAOK2,RAB33A,CLTC,NGEF,CNR1,FAM149A,COL11A2,ABI3BP,ZNF385A,AATK,SNCAIP,CSF1R,SEC24C,SLITRK5,GREB1,MYADM,ARHGAP32,TM9SF4,INTS1,PITPNC1,SPOCK3,TMCC2,SEC16A,SLC29A4,DPYSL2,ACOT8,TOM1,MBNL2,TNK2,ELN,RABEPK,SPEG,NRN1,CHST15,FCGRT,ZNF589,SLC9B2,FGF13,FGFR1,TMEM164,POLK,RGPD5,ANKFY1,NOP56,ERGIC3,TPPP3,FAM120B,B4GALNT1,DISC1,SEPT9,LRRC37A6P,CYP46A1,GFER,TNRC6A,MSL3,GNAO1,PRUNE2,TMEM121B,STMN2,SPACA9,ADAMTS13,GRIN2D,GRM2,GSN,GSTM5,AP4S1,RABL2A,UBE2QL1,PADI2,AGBL5,LRRC75A,SHISA6,SMAP1,RBPJ,TMEM240,LRRTM1,NME9,KCNK3,KHK,LINC00634,IPO5,TTYH2,STMN1,NCOA7,CLEC18A,MAN2A2,MATN2,MEST,MGAT3,AFDN,GIT1,MSI1,LYRM9,MYO7A,NF1,DNHD1,NPTX1,PCBP3,NTRK3,CDK18,PDE4B,PFKFB4,PIK3R1,KCTD15,PLEC,PNMA3,NECAB2,POLR2F,FSD1,PPP3CA,NKAIN4,CEP41,MASP1,NDUFS7,WBP1L,WDR25,ZSCAN2,TMEM231,CCDC40,ENOX1,ZNF493,OXR1,RASGRF1,TRIM68,RFX2,KIF7,RNASEL,RNH1,ARMC5,ROBO2,STK32B,RYR3,SEMA6D,PEAR1,GALNT10,MRAS,SH3BP2,FAM102A,DZIP1,FAM81A,SLC6A8,SLC11A1,EPC1,CXXC4,SMARCD3,SNAP25,FAM126B,ZSWIM8,SPTAN1,DDN,NFASC,LMO3,CLSTN2,ITPRID2,LARP4,SSPO,STAU1,ARHGEF9,ADAMTS17,COBL,EXOC7,KIAA0930,PCDHB15,PUM2,TNS2,HIF3A,CYB561A3,DICER1-AS1,TIAM1,CABIN1,RASD2,NPL,TRPM2,DCBLD1,RUSC1,CLEC2L,GORASP1,ZNF709,BCL2L13,PLPPR2,CLIP2,CLDND1,NPDC1,ZSCAN26,FTSJ1,ZNF213,MAP3K12,ITM2C,UBE3B,CASC15,RNF146,LAS1L" MicroRNA hsa-miR-101-3p.1:TargetScan hsa-miR-101-3p.1 TargetScan 1.32E-78 7.38E-75 1.00E-77 9.21E-77 156 671 "ASIC1,ELFN2,ADCY5,ADCY6,CCDC85A,AXIN2,PTCHD1,OSBPL1A,PCDH10,BEGAIN,OGT,DPP10,LRCH2,PPFIA4,APC,MARCH3,ATP2B2,MTMR2,JAZF1,LDLRAD4,CAMK2G,CBFA2T2,C1orf52,LONRF2,MAGI1,NOG,CLCN3,QKI,MYRIP,HAPLN1,ANKRD44,PPP1R16B,APPL1,CCDC144A,PYGO1,HDAC9,LONRF1,JAKMIP2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,ABCC5,EBF1,HIPK3,FEM1B,PHF20L1,MBNL2,EIF4G2,RGS17,ELN,MTSS1L,ERBB4,ETV1,EYA1,DLC1,FGFR3,MEX3B,PSD2,ATP2C1,DOT1L,GLI2,RAB30,KAT7,FAM222A,HAS2,BACH2,NEGR1,AGFG1,JAK2,KCNN3,KIF2A,KIT,IPO5,LIFR,PACRG,MARK1,MBNL1,MEIS2,KITLG,MITF,MSI1,MYCN,NACA,NOVA1,NPTX1,CLDN11,CNTN3,PCDH8,PCSK5,CDK18,PDE4A,PDE4D,ENPP2,GPR85,PIK3C2A,PCDH18,LRP12,FA2H,PPP2R5E,PTCH1,MARCH1,FAT4,RASGRF1,KHDRBS2,REV3L,FIGN,RFX3,NUDT11,PBRM1,ROBO2,FBXW7,RYR3,SALL1,SCN8A,CPEB3,FNDC3A,BTBD3,EPN2,ATF7IP,CXXC4,FAM126B,KDM3A,ARHGAP26,LMO3,POGZ,PRRC2C,ADAMTS17,PLCB1,ANKRD28,ANKRD12,MCF2L,PDLIM2,FBXW11,MGRN1,DMXL2,NSD1,PUM2,FRYL,NACC2,ASXL3,RIMBP2,KAT6B,RASD2,FLRT2,KCNK12,PCDH20,NDRG4,GDPD5,NAV3,HNRNPA3,ADAMTSL3,ADAMTS10,NETO2" MicroRNA hsa-miR-9:mirSVR_highEffct hsa-miR-9:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.37E-78 7.68E-75 1.04E-77 9.59E-77 222 1384 "ACADM,XKR4,PLEKHH1,PWWP2A,PTCHD1,HECW2,KLHL13,OSBPL6,CC2D2A,ALCAM,UNC79,ANK2,PKP4,PARG,APBA2,TNRC6C,ZBTB10,CCAR2,DPY19L3,TTLL9,MPDZ,NRP2,KSR1,SYNJ1,MTMR2,IL33,CALB2,KALRN,PTBP2,ZNF501,DGKI,LRBA,ARHGEF2,LRRFIP1,LOC730101,MAGI1,CDO1,NDST3,PLAA,FAM19A5,AKAP7,COL9A1,TBPL1,BAG4,MYRIP,NRG2,SEC31B,CLOCK,HAPLN1,GDA,CSF1,CSF2RA,ARHGEF10,VCAN,SOCS5,GREB1,CCDC144A,CYBB,KATNAL2,RIPOR2,ARHGAP24,MATR3,ARMCX2,JAKMIP2,RHOBTB1,SACS,FAM107B,EXOG,DMD,HS3ST2,USP3,CPEB2,PDCD6IP,E2F6,AASDH,CNNM1,RASGRP1,FRY,OPTN,MBNL2,AASS,TENM1,C8orf37,DCTN4,EPB41,TLR7,ABCA8,CHST15,GTF2IRD2,OLFM1,FGF12,FGFR1,ZBED3,UFM1,PDLIM5,TPK1,STAU2,GAD1,MTHFD2,C15orf41,PCDH17,LYVE1,SPIN1,TNRC6A,CBX1,GSTT2,ADAMTS6,MIER3,ACOT7,ZNF491,C9orf129,IRF8,IDH3A,ZIC5,LRRCC1,IL12A,JAK2,KCNN2,KCNN3,LMO2,NCOA7,LYPLAL1,MBNL1,MEF2C,MSI1,NRBP2,NEK1,NFE2L2,NRCAM,CHAMP1,OXTR,P2RY1,GPR137C,CNTN3,PDE4D,GPR85,PIK3R1,CCSER2,PLCL1,SLC25A23,PMP22,SEPT4,GRAMD1C,CNTLN,TMEM260,PTPRB,ZSCAN2,TUG1,ZNF793,RASGRF2,RADX,HKR1,RDX,RET,ERI2,MORC4,PBRM1,ZNF532,RPL15,MCMBP,GLDN,SGSM1,LRRK2,AP1AR,KIF21A,ARX,CPEB3,AMBRA1,NLGN1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,BTBD7,ATF7IP,CPEB4,ZFP1,OGDHL,LIMCH1,SNCA,CMTR2,TRERF1,RBM26,POGZ,SAMSN1,SS18,ARHGEF9,MTCL1,DOCK9,SLC19A3,USP32P1,FRYL,SIK3,SIRT1,AP4E1,ERCC6L2,NPL,PPIL6,UBE3A,UGT8,VSNL1,ZBTB14,ZNF19,TRIM9,TCEAL7,ZBTB38,EML6,MFF,DNALI1,ADAMTS9,KCNAB1,ITM2C,HRASLS,FAM13C,SMIM8,PHTF2,CASC15,ACTR3B,ADAMTSL3,NHSL1,FRMD6,DPF3" MicroRNA hsa-miR-144*:mirSVR_highEffct hsa-miR-144*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-78 9.66E-75 1.31E-77 1.20E-76 193 1050 "KDM5D,OLMALINC,MTUS1,PCDH19,KCTD16,RTL9,TXNDC16,ALCAM,ARHGAP20,BBOX1,CDC42BPA,LRCH2,APAF1,DDO,LGR5,MARCH3,NCOA1,ATP2A2,ALDH7A1,PROM1,SYNJ1,FUBP1,C5,RAB29,CALM1,KALRN,PTBP2,CAST,KRIT1,MTMR7,DLGAP1,TIGD7,CFL2,SRSF11,MS4A7,RAB33A,FBXO7,ARMC8,COL4A5,ENTPD4,HAPLN1,SNCAIP,LRIG1,SOCS5,PDE4DIP,BOC,DOCK4,HDAC9,RHOBTB1,EXOG,DTNA,EDN1,EDNRA,FCF1,KLHL5,FAM13A,MRO,MBNL2,AASS,ADGRV1,NRN1,CLVS1,ABCA8,FAM198B,ZNF585B,RPS6KC1,GORAB,FER,FGF13,SEMA4D,ATP13A4,ATP2C1,ST6GALNAC3,STAU2,MEGF10,ERAP1,MTHFD2,SULT1C4,SPIN1,GLUL,GNAO1,FERMT2,LNX1,GPD2,FUT10,ATP2B1-AS1,GRIA2,RABL2A,GUCY1B1,ZDHHC15,C2orf72,C2CD4C,KCNN2,LAMP2,STMN1,NCOA7,SMAD1,LYPLAL1,MBP,CHIC1,LRP1B,MEST,AFDN,ZNF680,MXI1,NCAM2,NF1,NOVA1,NOVA2,NUCB2,CHAMP1,CNTN3,PCDH8,PCSK5,GPR85,SEMA5B,CCSER2,PLCL1,PCDH18,TRHDE,EPB41L4B,DRAM2,MINDY2,PPP2R5E,PRKACB,PKIA,PRKCB,GRAMD1C,HYDIN,RELN,STK32A,PTPRN2,PID1,CEP97,SLC25A48,RAP1GDS1,RASGRF2,RDX,RET,ERI2,MORC4,GTDC1,RNASEL,ZFHX4,CCDC82,CARF,ATP8B4,TCP11L1,LRRK2,KCNIP3,CSRNP3,SUPT20H,CHD9,WDR37,FAM81A,CCDC88A,INTS9,RCOR3,TTC17,MBD5,CABCOCO1,RBM34,TRERF1,UHRF1BP1L,SPP1,PEG10,CLASP2,ZC4H2,SS18,DIP2A,SYPL1,TAF9,PDLIM2,PCDHB9,FRYL,ITGB3BP,NPL,VLDLR,WIPF1,RICTOR,ZNF17,KCNT2,MKRN3,ANKS1B,SMARCAD1,EMSY,ADAMTS9,HPS4,CIAPIN1,FIP1L1,PARP11,KAT6A,SENP7" MicroRNA hsa-miR-429:PITA hsa-miR-429:PITA_TOP PITA 1.78E-78 9.94E-75 1.34E-77 1.24E-76 171 818 "SYS1,XKR4,USP31,PTCHD1,SLC24A4,GPRASP2,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,SLC4A4,SYNJ1,FUBP1,JAZF1,SGCE,CACNB4,THSD7A,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,FAM19A5,MAP4K4,CNN3,CNTFR,CRHBP,NCOR2,CSNK1G3,PHACTR3,PLCXD3,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,KCTD8,IP6K1,GIT2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,PAN3,ERBB4,TAOK3,DLC1,AMOTL2,PRKAG2,MEX3B,FOXF2,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,SESN1,PPARGC1A,COPS8,FERMT2,GRB10,CIT,PSIP1,MAP4K5,BACH2,MIER3,HLF,NEGR1,AGFG1,KCND2,NCOA7,MAP2,LRP1B,AFF1,MYCN,MYT1,ZC3H12B,NFYA,CNOT4,NOVA1,NPTX1,GPR137C,PCDH8,PDPK1,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,PPP2R2C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,PTPN13,OXR1,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,PUM2,FRYL,ZFPM2,ERCC6L2,LRRC8A,NR2C2,VLDLR,TBC1D15,WIPF1,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,PHTF2,FXR1,GAN,SENP7" MicroRNA hsa-miR-4290:mirSVR_lowEffct hsa-miR-4290:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.93E-78 1.08E-74 1.45E-77 1.34E-76 229 1472 "SYN3,SYS1,GALNT16,ADD2,MTA3,SLC24A4,KCTD16,SEMA6A,CEP126,LTBP4,PDZD4,PITPNM2,ANK2,SUGT1P4-STRA6LP-CCDC180,APBA2,PPFIA3,SPTBN4,STK33,PCDHGB4,ATP1A1,ADAM15,ADGRB1,ADGRB3,BBS2,ARHGEF7,JAZF1,MYRF,CFAP410,CA4,CALB2,KALRN,CAST,ARHGEF25,CBR1,USP6,ARHGEF1,ARHGEF2,EVI5L,MAGI1,TAOK2,ARHGAP22,MYL6B,MAP4K4,GAL3ST1,ZFP28,CNRIP1,C2CD2,NCOR1,SEC24C,CSNK1E,PLXNA4,KIAA0040,ARHGEF4,RUBCN,ZNF337,TM9SF4,DAPK1,ARMCX4,B3GAT3,RUSC2,C2CD2L,GSDME,GUCD1,TMCC2,EXOG,DMD,DTNA,DNAJB6,ABCC5,FIS1,PHC2,HIPK3,KLHL5,FAM13A,APH1A,TMEM132E,GOLGA7,RGS17,DCTN4,EPB41,SRRM1,EZH1,KAT8,GTF2IRD2,OLFM1,FGF13,MAD2L2,AGAP2,EVL,POMT1,TMEM107,ZNF605,ERGIC3,CELF1,GABBR1,ZNF44,CHL1,GABRB3,DISC1,ALDH1L1,TUBA8,CSDC2,ZNF276,CRCP,GLYR1,RAB30,LUZP2,SPACA9,ADAMTS13,RABL2A,FAM107A,ATOH8,HLF,AGBL5,ICA1,FAM95B1,INPP5B,SLC6A17,ITPKB,CDH20,KCNB1,KCNK3,A1BG-AS1,MAT2A,ADAM11,PPM1L,MPP2,HNRNPM,NNAT,VWA2,NTRK3,IGSF11,CLDN11,PCDHGC3,CDK18,PDE3A,GNG2,PFKFB2,NLGN3,PLCB2,PLCL1,PRIMPOL,POLR2F,PRKAB2,PRKCB,WBP1L,WDR25,CNTLN,PTN,ZSCAN2,QDPR,FAT4,NWD1,RASGRF2,RGS12,PBRM1,CYB561D1,MRAP2,SNX22,KIAA0895L,RXRA,FAM192A,SARS,CASC3,SHMT2,FHOD3,SLC6A8,SLC9A5,SLC12A2,NAPB,CXXC4,CDK5RAP2,IFT122,MAPKBP1,SNRPN,SOX3,TSNAXIP1,DDN,LHPP,CLSTN2,SSPO,MPRIP,CEP68,DIP2A,PHLDB1,KANK1,ARHGEF9,ADGRL3,SATB2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,HIF3A,TMEM121,THRA,TK2,PIK3R5,C9orf85,TRPS1,NUTM2A,LINC00689,FLRT2,VIPR2,WIPF1,ZNF70,CELF4,AMZ1,EML6,MEIS3,PRTFDC1,PRDM8,KCNAB1,ITM2C,PCBP4,SMIM8,PHTF2,FAM181A,LAS1L" MicroRNA hsa-miR-148a:mirSVR_highEffct hsa-miR-148a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.10E-78 1.18E-74 1.59E-77 1.46E-76 202 1152 "CLK4,TMEM132B,CCDC85A,AP2A2,HECW2,KCTD16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,MARCH4,PCDH10,PITPNM2,AMPD3,NCOA1,STX16,ADAM23,ADGRB3,DST,SYNJ1,SYNJ2,GPC2,LURAP1,CABP7,CAST,USP6,MAGI1,NOG,CFL2,SRSF11,B4GALT6,PLAA,QKI,AKAP7,ARMC8,FAM149A,ABI3BP,CLOCK,SEC24C,ERC2,RUBCN,BOC,GAPVD1,MATR3,KIAA0586,TMEM170A,YTHDC1,ZNF804A,HEPH,SNAP91,SACS,WDR20,RAB39B,DMPK,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,COPS4,TNK2,TLR7,ACSL4,SCML2,FCGR1A,FER,MED12L,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,ATP2C1,TVP23A,NEURL4,ZNF274,C15orf41,DISC1,KIAA1841,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,RAB40B,PCLO,DIDO1,RNF165,KAT7,TNFAIP8L3,ELOVL5,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,MAT2A,MATN3,MBD1,TM6SF1,PPM1L,MITF,ZNF680,NDP,NF1,CNOT4,DNHD1,NPTX1,NPTX2,PCDH9,PDE1C,SLC10A4,PFKFB2,PIK3C2A,JAKMIP1,PLIN1,TRHDE,EPB41L4B,PPM1B,TATDN3,PPP3CA,KANSL1,RASGEF1B,MAPK7,MAPK10,GRAMD1C,SNRK,MTMR10,PTPRD,EML5,PTPRN,PPP2R3C,TMEM255A,SH3TC2,FAM184A,RBBP6,DPF2,SLC25A36,RNASEL,ZFHX4,PNMA8A,ROBO1,ROBO2,RORB,ELP2,SATB1,CHD9,FBXO11,FNDC3A,ABLIM3,FAM81A,BTBD3,WDR47,SMARCA4,LMBRD1,SNRPN,USP33,SP4,ZC3H13,CDK19,ITPRID2,NKAIN2,RGL1,VPS13A,MTCL1,ZEB1,RPGRIP1L,TCF12,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,NACC2,TNS1,TPM1,UBE2H,BCL2L13,P2RY12,ZNF24,SPIRE1,LINC02210,STOX2,MDH1B,EPM2A,ST7,RTN4,PHTF2,FXR1,JPH3" MicroRNA hsa-miR-1291:mirSVR_lowEffct hsa-miR-1291:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.30E-78 1.85E-74 2.48E-77 2.28E-76 237 1576 "DGCR6,ASIC1,NCKAP5,GALNT16,ADCY6,ADORA2A,PTCHD1,PCDH19,TBC1D14,ADGRF5,UNC79,DOC2A,AMPD2,AMPH,PI16,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,FAM131A,APOC2,USP37,ASGR1,TTLL9,ADGRB1,ADGRB2,BBS2,NRP2,KSR1,BTK,KALRN,RHBDL1,ENTPD6,AP4M1,ARHGEF2,LARGE1,NGEF,QKI,RAB26,CNGA3,SMARCAL1,SH2B1,SNCAIP,ARHGEF4,GPSM1,BOC,CENPL,RASSF2,ARMCX4,TIAM2,KIAA0753,C2CD2L,POM121,RHOBTB1,SGSM2,TMCC2,DMPK,HS3ST2,SLC29A4,DPH1,DPYSL2,EDN1,FRY,SUGP2,RASA4,KCTD3,TNK2,CERCAM,VPS13B,COQ7,RASGRP2,ANKMY1,TLR7,SIRPB1,MRVI1,F5,REEP2,PTK2B,ZSCAN30,GTF2IRD2,FGF11,FGFR3,MEX3B,HPCAL4,SYNCRIP,AGAP3,NOP56,FLYWCH1,C2orf88,POMT1,SMC2,CELF1,CGREF1,HHIPL1,BRSK1,HRASLS5,GALNT15,B4GALNT1,ACSS1,LRRC37A6P,TUBGCP4,TUBA8,GLYR1,MSL3,KCNMB4,FERMT2,MCHR1,GRIN2C,GRM2,GSN,RNF165,ZBTB45,NCKAP1L,HMGCL,CFAP126,DHX35,LRRC75A,IRF8,MYLK2,NKD1,GAREM2,RBPJ,KNDC1,TJAP1,IL6R,INSM1,KCNJ5,KCNN3,LINC00634,SYTL4,LSS,MEF2C,MEIS1,MGAT3,XRRA1,MN1,MSR1,PTOV1,NRBP2,MXI1,HNRNPM,NNAT,NOVA2,NPTX2,OXTR,PAX6,PDE1B,PFKFB4,TMIE,ZNF655,XRN1,SLC25A23,RETREG2,POLR2F,NKAIN4,PRKCB,MAPK3,KLK6,PIGG,PTPRD,PTPRE,PTPRO,ZSCAN2,TUG1,SLC25A48,CCDC40,ROGDI,RASGRF2,RBBP6,HKR1,TRIM68,RGS12,PRIMA1,SLC25A36,PBRM1,CCDC102B,SNX22,RPL15,KIAA0895L,ATP8B4,ADAL,ST6GALNAC6,ZNF568,MAPK12,FERMT1,ASAP3,CPEB3,ST6GAL1,ABLIM3,SLC8A1,SLC9A5,SLC11A1,KIF13A,FAIM2,SNRPN,MYO16,TSNAXIP1,NMNAT2,SPTB,IQSEC2,TSPYL2,NFASC,SSPO,DIP2A,SEPT3,SUPT5H,MLST8,TAL1,FBXW11,SMG6,KLHL4,TPCN2,SZT2,FAM189A1,GPRIN3,CYB561A3,ARL10,ENHO,RELL2,CDK20,ZNF346,TRO,TRPM2,TTTY15,HIRA,CLEC2L,KLC2,GUSBP1,CELF4,SIGLEC10,WNK2,HNRNPA3,FBXO36,CASC15,FAM219B,ADAMTS10,LAS1L" MicroRNA hsa-miR-4322:mirSVR_lowEffct hsa-miR-4322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.30E-78 1.85E-74 2.48E-77 2.28E-76 229 1476 "RALGAPA1,EMILIN3,SYS1,FMNL2,GALNT16,ADORA1,KCTD16,WDR35,PCDH10,LRFN1,ZFAT,SUGT1P4-STRA6LP-CCDC180,FAM131A,SEMA4G,MADD,MARCH3,ADGRB2,RGS9,BTK,IL33,KALRN,RHBDL1,ARHGEF1,ENTPD2,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,NRXN3,CLTC,QKI,FHL5,CNTFR,IQCK,SMARCAL1,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,ARHGEF10,CTH,GREB1,BOC,HDAC9,MYADM,ZNF337,IP6K1,DGCR5,HEPH,TIAM2,FBXL5,KIAA0753,SV2B,CD99L2,CDON,ARRDC4,TOM1,EDN1,EDNRB,YAF2,PHF20L1,APH1A,EGFR,KMT5B,IRAK4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,MRVI1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,FLT1,NOP56,CINP,CELF1,ST6GALNAC3,NEURL4,HRASLS5,B4GALNT1,SEPT9,ALDH1L1,TUBGCP4,TTBK1,ZNF638,MAP7D2,POLL,PRUNE2,STON1,MCHR1,RNF165,FAM107A,ADAMTS6,HMGCL,HNF4G,DHX35,CELF5,MYLK2,LRRC25,INSM1,C2CD4C,SLC35G1,KCNH2,SFXN5,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,MYO5A,MYO7A,CLDN11,OXTR,P2RY1,CDK18,NALCN,FAM218A,CCSER2,PLCB2,MAPKAP1,FA2H,POLR2F,PPARA,PRODH,MASP1,RELN,WDR25,ZSCAN2,CCDC40,NWD1,RASGRF1,GTDC1,CARF,ROBO2,CCDC25,SNX22,SGSM1,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,KCNIP3,RYR3,LRFN5,SCP2,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,FERMT1,SHMT2,WDR37,LIMS2,KANSL3,PKNOX2,SLC6A8,BTBD7,LGI3,KIF13A,SNRPN,FAM219A,TSNAXIP1,SPTAN1,IQSEC2,CLSTN2,ZC4H2,SSPO,SEPT3,JMJD6,COBL,TACC1,MTCL1,MLST8,IQCE,CLASP1,SZT2,SYNE1,FRYL,CYB561A3,GALNT17,TMEM9,ERCC6L2,RIMBP2,CABIN1,WBP2,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,VLDLR,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,NDRG4,ZBTB38,ZNF154,AMZ1,DPYSL5,PCBP1-AS1,ZNF213,DNALI1,TMEM63C,RNF170,GAN,JPH3" MicroRNA hsa-miR-339-5p:mirSVR_lowEffct hsa-miR-339-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-78 2.18E-74 2.93E-77 2.69E-76 233 1527 "PSMG3-AS1,ADCY6,RNF157,ADORA2A,SLC24A4,ZNF578,TAOK1,C1QTNF3,PDZD4,CDC42BPA,EP400,PPFIA4,APAF1,TNRC6C,IGDCC4,SPTBN4,ARRB1,MARK4,NUMB,RNF182,DPY19L3,RGS9,HCN2,NRP2,BMPR1B,SGCE,SPAG9,USP2,MTMR7,ENTPD6,AP4M1,LOC730101,CCPG1,ASIC3,NDST3,EPS15L1,TPP1,STOML1,FBXO7,COL11A2,ZNF521,IGDCC3,ANKRD44,NCOR2,SNCAIP,CSF1R,RGS6,CSNK1G3,PDE4DIP,UBXN2A,PPP6R2,GAPVD1,RIPOR2,RASSF2,TMEM170A,DAPK1,SCRN1,ZC3H11A,SNAP91,ZNF582-AS1,EXOG,DNM1,USP3,HIPK3,EGFR,C3orf18,DCTN4,VPS13B,EPB41L2,COQ7,RABEPK,DENND4A,NCALD,VPS26C,F5,REEP2,FAM198B,TBC1D16,ZNF589,FGF11,TMEM164,FHL1,AGAP3,FLT1,ANKFY1,EFCAB2,POMT1,PDLIM5,RASL10A,ERGIC3,CGREF1,ABLIM2,TVP23A,GABRG1,DISC1,GFER,CRCP,LUZP2,KCNMB4,PRUNE2,PLCD4,GRM8,LINC01089,GSTM5,MAP4K5,ATXN2L,ARHGAP36,GABARAPL2,SYNPO,ZNF491,TCEAL6,FAM95B1,ITGA7,GPR62,KCNN2,A1BG-AS1,HECTD2,ZFYVE27,MAP4,BLOC1S2,MSR1,MXI1,NCAM2,NME4,CNOT4,DNHD1,SLC11A2,NTRK2,GLIPR1L2,PDE4D,PFKFB3,PFKFB4,NLGN3,NLE1,PLCB2,MAGEL2,PPM1B,TATDN3,PPP2R2C,PRKACB,GRAMD1C,CYBC1,DEF8,WDR25,BDNF-AS,PTH1R,SPDL1,PTPRB,PTPRO,USP47,SH3TC2,GTDC1,RIC8B,RPL15,STK32B,HSD11B1L,ZNF331,ASAP3,HKDC1,AMBRA1,FHOD3,ANKRD6,WDR37,PEX26,EPN2,SLC6A8,RADIL,SIRT2,SLC9A5,SLC12A2,ARFGAP1,OGDHL,MYH15,TMCC1,FNBP1,ZSWIM8,SP4,KDM4C,UNC5B,TSPYL2,ERBIN,SEPT8,PHLDB1,PRRC2C,SYNE2,ARHGEF9,SYN2,SYP,TACR1,EXOC7,FAM208A,ALG1,ADGRL3,DMXL2,SATB2,ZFP90,CLASP1,DOCK9,CYB561A3,DICER1-AS1,SLC44A1,GALNT17,THRA,TPM2,DOK6,ZNF346,SMUG1,NEIL2,STXBP4,TSC1,ZNF709,VIPR2,GUSBP1,CFAP298,ZNF711,MKRN3,CELF4,ZNF154,TMEM237,EML6,SLC30A4,EMSY,NT5M,DNALI1,LINC02210,TUBA1A,CIAPIN1,NAV3,FIP1L1,UBE3B,FBXO36,CASC15,MSRB3" MicroRNA hsa-miR-3152:mirSVR_lowEffct hsa-miR-3152:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-78 2.43E-74 3.25E-77 2.99E-76 220 1368 "TMEM132B,GALNT13,PTCHD1,MTUS1,PCDH19,RTL9,TBC1D14,AK2,SEMA6A,FAM135A,ZNF687,LCORL,MAP4K3,APC,LGR5,SEMA4G,CASK,ZBTB10,ZNF583,N4BP2L1,DPY19L3,KIF1A,TTLL9,BID,KSR1,ARHGEF7,MTMR2,PTBP2,CAMK2G,VXN,SPAG9,LRBA,CACNA2D2,DIS3L,CHN1,IGDCC3,CLOCK,PREPL,C1QL2,SNCAIP,LRIG1,ARHGEF4,DOCK4,RIPOR2,DCAF8,LONRF1,KIAA0586,SPATA2,JAKMIP2,GRIN3A,RAB39B,DMD,DNM1L,EDN1,KLHL5,FAM13A,PHF20L1,MRO,MBNL2,ASB3,PLEKHA1,STARD3NL,USPL1,EPHB1,ERBB2,DENND4A,CEP85L,SIRPB1,MRVI1,ST3GAL6,MEX3B,FOXF2,ANKFY1,PSD2,EFCAB2,POMT1,PDLIM5,ERGIC3,ABLIM2,FYN,MEGF11,ZNF234,IQGAP2,ERAP1,KIAA1841,CSDC2,ZNF276,SPIN1,GLI2,TOX3,GLUL,CCDC184,GPR34,SPACA9,GRIN2C,LINGO1,GUCY1B1,FAM222A,RASSF8,HMGCR,NEGR1,GAREM2,INPP5B,STXBP5,GPR155,LYPLAL1,MATN3,CHIC1,LRP1B,SAMD5,ADAM22,N6AMT1,NDP,NELL2,NFE2L2,VWA2,CNOT4,NOVA1,SLC11A2,NUCB2,OPA1,PCDH9,PDE4B,PDE4D,PFKFB3,NALCN,PIK3C2A,PLCL1,MTRF1L,PDZRN4,PMP22,ING3,EPB41L4B,PILRA,PPARA,RANBP3L,PRKAB2,RASGEF1B,PRKACB,PKIA,CNTLN,PTCH1,SPDL1,PTPN13,TMEM231,MARCH1,TMEM255A,FAT4,ROGDI,RBBP6,DPF2,SLC25A36,SALL1,SEMA6D,SCN7A,SGK1,SHC4,CHD9,CNKSR2,WDR47,PKNOX2,SIRT2,CCDC88A,SLC12A2,SLC22A4,TET1,SNRPN,FAM219A,BDP1,HECW1,POGZ,ITPRID2,ZC4H2,SS18,SEPT8,PLCB1,SYPL1,COBL,MTCL1,FAM208A,ADGRL3,KLHL4,ATMIN,SATB2,TRIM2,PCDHB10,OBSL1,FRYL,DICER1,SIRT1,ZMAT3,TIAM1,BHLHB9,CSMD1,PIK3R5,RGMB,TSN,TSC1,TTC3,UGT8,RBFOX3,WRN,RICTOR,PCDH20,ZNF17,MKRN3,LYPD6,ZBTB38,EML6,ANKS1B,EMSY,DNALI1,FAM47E,FAM13C,AMN1,FZD3,FRMD6,IFT88,NETO1,RNF146" MicroRNA hsa-miR-338-5p:PITA hsa-miR-338-5p:PITA_TOP PITA 4.78E-78 2.67E-74 3.58E-77 3.30E-76 166 773 "CLK4,FMNL2,PLEKHH1,PTCHD1,HACE1,OSBPL8,SEMA6A,SPOP,ARHGAP20,FAM135A,CDC42BPA,DPP10,MAP4K3,APBB2,CDC14B,TMEFF1,ZBTB10,SLC4A4,ATP2A2,SYNJ1,WASF1,CALM1,LDB2,C1orf52,LRBA,ZMYM4,LARGE1,MAGI1,B4GALT6,SLIT2,RAB28,NRXN3,CLTC,ARHGEF6,CNR1,ARMC8,COL4A5,PUM1,KIAA0408,BOC,HDAC4,ZFYVE16,DGKG,JAKMIP2,MYEF2,MTX3,WDR20,DMD,CDON,CPEB2,CASP8AP2,GOLT1B,TMTC1,MBNL2,EGR3,TENM1,PAN3,DENND4A,EYA1,ACSL4,TAOK3,SCML2,FGF13,AMOTL2,AFF2,NBEA,STAU2,GCNT2,MSTN,PCDH17,GHR,PPARGC1A,FERMT2,GRB10,GRIA2,CIT,FAM222A,MIER3,NEGR1,RBPJ,LRRCC1,MARK1,MBNL1,MEIS1,AFDN,MN1,MYCN,NEXMIF,NF1,NNAT,NPTX1,PCDH9,PDE4B,ENPP2,GNG2,PIK3C2A,PIK3R1,KCTD15,TRHDE,LRP12,SCHIP1,EPB41L4B,GDPD1,RELN,SNRK,PTCH1,PTPRD,TMEM255A,OXR1,RGS4,RIC8B,CLIP1,SAFB,TRA2B,KIF21A,PPM1E,CPEB3,FBXO11,FNDC3A,R3HDM2,WDR47,SEPHS1,CPEB4,RCOR3,MBD5,KDM4B,DOP1A,SOX11,SP2,SPART,CLASP2,SS18,VPS13A,ADAMTS17,PLCB1,SYPL1,SYT1,ANKRD12,CAMTA1,TAF6,FAM208A,TCF4,SATB2,DOCK9,PUM2,TEK,DICER1,SIRT1,CSMD1,RUNDC3B,TRPS1,TSC1,SGK3,UBE3A,WIPF1,PCDH20,ZIC2,ZNF711,TRIM9,LYPD6,ZFAND5,SMARCAD1,ADAMTS9,FAM13C,JMJD1C,SENP7" MicroRNA hsa-miR-3174:mirSVR_highEffct hsa-miR-3174:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.86E-78 2.72E-74 3.63E-77 3.35E-76 185 969 "KCNH8,KLHL32,GALNT13,ADD1,PLEKHH1,PWWP2A,CC2D2A,HFM1,C1QTNF3,SMIM17,ALCAM,CEP126,FAM135A,ALK,AMT,OGT,PARG,APC,LGR5,ATP2A2,N4BP2L1,ADGRB2,ADGRB3,DST,IL33,CA8,PTBP2,CBR1,MTMR7,C1orf52,CDH2,LRRFIP1,CCPG1,DIS3L,RCBTB2,CHGB,B4GALT6,CNOT8,QKI,AKAP5,ABI3BP,BAG4,SEC31B,CREM,GDA,LRRC3B,PDE4DIP,CST3,UBXN2A,KATNAL2,KIAA0586,DGKB,BRINP1,SACS,FAM107B,CHRDL1,GRIN3A,ABCC5,EDNRA,HIPK3,SUGP2,EGFR,GOLGA7,PAN3,EPB41L2,EPHB1,TAOK3,FGF1,SUCO,ANKFY1,NBEA,PDLIM5,GABRG2,DISC1,LRRC37A6P,KDM2B,ADGRA3,CNTRL,FAM19A2,KAT7,PSIP1,PADI2,ATXN2L,HNMT,DHX35,SHISA6,IDH3A,JAK2,SLC35G1,IPO5,NCOA7,MARK1,MATN2,TM6SF1,KCTD6,KITLG,MID1,PPM1L,MITF,NELL2,NF1,SLC11A2,IGSF11,PCSK5,PDE4B,ENPP2,PDPK1,ZFYVE21,PCDH18,PMP22,TRHDE,ING3,MINDY2,KANSL1,GRAMD1C,DIRAS2,PRPSAP2,WBP1L,CNTLN,BDNF-AS,PTPRB,ZSCAN2,SUSD4,MSANTD2,FIGN,RNASEL,TMLHE,KLHDC8A,LRRK2,ATAT1,COPZ1,DZIP1,SEPHS1,ZNF415,SNRPN,TMCC1,KDM4C,ZC3H13,MCF2L2,CLASP2,TROVE2,NKAIN2,ERBIN,NXT2,STAU1,SEPT8,TTBK2,TBCEL,TPCN2,RPGRIP1L,GPRIN3,SIK3,SIRT1,AP4E1,SLC44A1,THRA,TMEM9,TMPO,SYNPO2,RUSC1,KCNE5,CLHC1,FAM155A,UGT8,FLRT2,P2RY12,PCDH20,ZNF540,MKRN3,LYPD6,ZNF184,ANKS1B,SH3GLB2,SMARCAD1,EMSY,DNALI1,EPM2A,ST7,KAT6A,HNRNPA3,PHTF2,CASC15,NETO2,FAM198A,JPH3" MicroRNA hsa-miR-1914:mirSVR_lowEffct hsa-miR-1914:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.52E-78 3.65E-74 4.87E-77 4.48E-76 221 1383 "ABHD6,NDRG2,KLHL32,TMEM132B,ADD2,AP2A2,SRPX,EP400,MAP4K3,SUGT1P4-STRA6LP-CCDC180,DDO,LGR5,CDK10,IGDCC4,ARNTL,STK33,NCOA1,CCAR2,SLC2A11,ALDH7A1,ADAM23,TTLL9,BCHE,RGS11,RGS9,SYNJ2,ARHGEF7,JAZF1,SGCE,CABP7,VXN,TIGD7,NRXN3,CLTB,FAM189A2,HECTD1,COL4A5,COX4I1,CREM,AATK,SEC24C,VCAN,RASGEF1C,FAM169A,CCDC144A,LONRF1,DGKG,ELMSAN1,DGCR5,KLHL3,ZC3H11A,GUCD1,SNAP91,DMD,CD99L2,SLC12A6,DPH1,DPP6,PDCD6IP,ARRDC4,DTNA,ABCC5,EDIL3,SNX29,EGFR,PLXNC1,TMEM132E,GOLGA7,TMEM35A,EIF1,EPB41,EPB41L2,RCAN2,SRRM1,NCALD,ADGRV1,EZH1,FAM198B,TMEM132C,PTK2B,SCARA3,EFCAB2,WDR83,TMEM107,CAMKK2,ZNF605,ERGIC3,ZNF274,INPP5K,ACSS1,TUBGCP4,GPR162,CYP46A1,GFRA2,FREM1,SPIN1,RAB30,TOX3,LUZP2,PRUNE2,DIDO1,SERP2,AP4S1,RABL2A,SOX21,FAM107A,SLC2A6,RASSF8,DDX19B,SYNPO,AGBL5,CPT1C,AGFG1,GAREM2,KIAA1755,IBA57,INSM1,JAK2,KCNN3,KIF2A,KIF5A,LSS,ASPRV1,MAP6,SCAMP5,XRRA1,DBNL,MSR1,PTOV1,LAYN,RTL5,NDP,NFIX,SETD4,CDK18,PDE4A,PDE4B,PDPK1,OLA1,PCDHB17P,PPP2R5E,RASGEF1B,MAPK4,TMEM260,CASTOR1,RAD51D,OXR1,RASGRF2,RDX,CRTAC1,KCTD17,RNASEL,CARF,MRAP2,EPHA10,GLDN,MEG3,ZNF331,ATXN2,SUPT20H,AMBRA1,FHOD3,NLGN1,DZIP1,SLC4A3,FAM81A,EPN2,KANSL3,SLC12A2,ATF7IP,SLC22A4,ABTB1,SMARCA4,CDK5RAP2,LIMCH1,SNRPN,FAM126B,NMNAT2,ZC3H13,ARHGAP26,RBM26,CLSTN2,POGZ,ERBIN,STAU1,KANK1,SULF2,ARHGEF9,VPS13A,SYN2,SLC37A2,TACC1,WSCD1,TPCN2,SZT2,DOCK9,PUM2,SIRT1,DICER1-AS1,ZFPM2,GALNT17,ELP5,DCBLD1,RUSC1,SSBP2,UBE2H,LINC00689,BCL2L13,CLIP2,XRCC4,ZIC1,ZNF711,CELF4,DPYSL5,ANKS1B,ZNF213,MEIS3,RGS7BP,UBE3B,PHTF2,TIGD6" MicroRNA hsa-miR-3134:mirSVR_lowEffct hsa-miR-3134:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.68E-78 3.74E-74 4.98E-77 4.59E-76 216 1323 "ACTN1,TMEM132B,GALNT16,RNF157,ESYT2,OSBPL6,SMIM17,SRPX,CCDC146,PHF12,APC,APLP1,VAT1L,BCAS1,CDC14B,LINC00173,MARK4,NUMB,TMEM108,ATP1A1,STX16,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,ADGRB3,DST,SCAPER,CASTOR3,C5,CACNB4,SLC25A14,SEPT7,LARGE1,DLGAP1,CHN1,NRXN3,IQCK,MYRIP,CLOCK,ANKRD44,NCOR2,GDA,RGS6,SEC24C,VAC14-AS1,SLITRK5,ERC2,CCDC144A,HDAC9,GAPVD1,TBC1D5,KIAA0586,IP6K1,ELMSAN1,HEPH,MYEF2,MFAP3L,TMEM130,SV2B,MTX3,DNAH9,DOCK2,DPH1,CASP8AP2,MBNL2,KMT5B,TMEM132E,EIF4G2,ELN,CALCRL,GPHN,MRVI1,TMEM132C,TUBA1B,TAOK3,SCML2,RACK1,CEP78,MED12L,IP6K2,PCYOX1,SLC37A3,MEGF10,HRASLS5,GALNT15,GABRG1,DISC1,IGSF5,ALDH1L1,GCNT2,ADAM28,USP19,SPIN1,TOX3,HTATSF1,PCLO,FAM19A2,ADAMTS6,PADI2,FRMD3,HLF,HMGCL,IRF8,IGF1,ITGAM,KCNJ5,KIF2A,PAXBP1,MARK1,MBD1,MBNL1,CHIC1,MEIS1,MPP2,ZNF680,MXI1,MYO6,NFIX,CNOT4,NOVA1,NTRK3,TBC1D25,OPA1,PDE1B,OLA1,PIK3R1,ZNF655,CCSER2,GPSM2,PURG,PDZRN4,SDK2,PPP2R2C,PKIA,HYDIN,VPS13C,WDR25,PTPRD,PTPRO,TMEM255A,USP47,SH3TC2,RAP1GDS1,ZNF493,RADX,ZMAT4,TRIM68,REV3L,CCDC82,C12orf49,PNMA8A,ROBO1,MRAP2,NEK11,SGSM1,LRRK2,ATAT1,STX1B,ZNF331,CASC3,FOXRED1,TRA2B,COPZ1,ZFP30,FBXO11,FNDC3A,SLC12A2,SLC12A4,ATF7IP,GKAP1,DOP1A,UNC5B,POGZ,LARP4,NEK4,SEPT8,RGL1,KLHL7,JMJD6,SYN2,ANKRD28,TACR1,MTCL1,ADGRL3,ZEB1,RPGRIP1L,PCDHB9,PCDHB7,FRYL,AP4E1,GPR161,TIAM1,HEY1,BEX4,TNS1,NPL,DOK6,TSC1,WIPF1,LAT2,ZIC2,ZNF19,MICU3,LYPD6,ZNF142,SPIRE1,SMARCAD1,PARP11,FAM13C,KAT6A,NLRP3,SOCS4,ST8SIA2,CPNE4,FAM198A" MicroRNA hsa-miR-8485:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.29E-78 4.64E-74 6.17E-77 5.68E-76 176 877 "TMEM132B,ESYT2,PTCHD1,MTA3,TAOK1,PDZD4,AMPD3,LRFN1,TNRC6C,CADPS,ATP1A3,ATP2A2,DPY19L3,BACH1,JAZF1,CA8,CACNA1B,KALRN,LONRF2,CDH2,TBRG4,CRLF1,CFL2,B4GALT6,STOML1,TMEM184B,COL9A1,TBPL1,TOGARAM2,NRG2,CRY2,ANKRD44,PLXNA4,KIAA0408,HDAC9,MYADM,RASSF2,LONRF1,DGKG,SPOCK2,DNAL1,DBT,KLHL3,SV2B,MTX3,FAM107B,CHRDL1,DTNA,EGR3,PLXNC1,EIF5,TMEM35A,C8orf37,TUBD1,ACSL4,CHST15,FGFR3,FOXF2,SYNCRIP,FLT1,AFF2,ZBED3,MPP6,HRASLS5,MTHFD2,SYT17,SEPT9,SRRM4,GCK,SRCAP,MMADHC,PPARGC1A,GLYR1,PARD3B,CACFD1,GSN,GSTM5,PADI2,FRMD3,BACH2,HLF,HMGCR,MSL1,C2orf72,SCIN,IL6ST,IBA57,ITPKB,JAK2,KCNB1,KLHL23,IPO5,LAMP2,SYTL4,AFF1,MPP2,HS6ST3,NEXMIF,NPTX1,P2RY1,PDE3A,GPR173,TMOD2,PIK3R1,PKD1,PLCL1,PLIN1,PPM1B,DIRAS2,SNRK,PTCH1,SH3TC2,IQSEC3,RDX,ZMAT4,GTDC1,C12orf49,PNMA8A,KIRREL1,HUNK,ATAT1,STX1B,SEMA6D,SBF1,CSRNP3,SCN8A,TRA2B,CPEB3,WDR37,SLC12A2,ATF7IP,SLC22A4,ZFP1,KIF13A,FAM126B,MYO16,PDZD2,TRERF1,FNBP1,UNC5B,ZNF621,SS18,SEPT3,NECAB1,RHBDL3,SYT1,ASTN2,SYT5,TAL1,TCF12,CLASP1,NAT16,GPRIN3,SIK3,SLC44A1,GALNT17,NACC2,BHLHB9,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,NDRG4,CRB2,SLC30A3,SLC30A4,ZXDA,ADAMTS9,HPS4,WNK3,FAM198A,SPATA13" MicroRNA hsa-miR-634:mirSVR_lowEffct hsa-miR-634:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-77 6.66E-74 8.86E-77 8.15E-76 232 1523 "KCNH8,ACADM,SYS1,METAP1D,NDRG2,UNC5A,KIAA1211,RNF150,FAHD2CP,SLC24A4,MTUS1,CC2D2A,MARCH4,FAM135A,AMT,ANK2,MAP4K3,PKP4,VAT1L,PPFIA3,CASK,BMPR1B,BTK,MTMR2,CACNA1G,C5,CAPN3,VXN,SRSF11,CNOT8,ARHGAP22,QKI,HECTD1,WHRN,COL11A2,HAPLN1,HINFP,NCOR1,CSF1,RGS6,LRIG1,ARHGEF10,VAC14-AS1,CNTNAP2,APPL1,RUBCN,MYADM,KATNAL2,DCAF8,EARS2,LONRF1,TM9SF4,IST1,DAPK1,MYEF2,RUSC2,KIAA0319,TMCC2,ZNF582-AS1,GRIN3A,DMTF1,RCAN1,MAMLD1,DNAJB6,ABCC5,EDN1,TMTC1,EGFR,TENM1,USPL1,EPB41,STX2,NCALD,SPEG,MRPL37,DNAJC27,ADGRV1,F8,FER,FGFR1,FGFR3,AMOTL2,COQ5,CAMKK2,ATP2C1,PRELID3A,RAPGEF6,ALDH1L1,PCDH17,RNPS1,GLI2,DCLK2,LOXL3,PCLO,CLASRP,ADAMTS6,FRMD3,HMGCR,HNMT,ZNF491,SMAP1,FAM95B1,GAREM2,RBPJ,ZNF678,INPP5B,ITGA7,SLC35G1,KCNN1,KCNN2,KCNN3,SYTL4,MAP6,MAT2A,MBP,TM6SF1,SAMD5,MYO9A,NDP,NFE2L2,NINJ2,NOVA1,NPR2,NTRK2,NUCB2,OPA1,ETFRF1,PCSK5,GNG2,PFKFB2,PIK3R1,ZNF655,NLE1,EXOSC10,SCHIP1,ING3,POLG,RASGEF1B,CEP41,DEF8,PTN,ZSCAN32,PTPRE,PTPRO,TMEM145,NKAIN1,TMEM255A,NWD1,ZCWPW1,ROGDI,ZNF493,RDX,C12orf49,ALG9,GSTCD,ELP2,RPL15,GLDN,LRRK2,RXRA,SALL1,SEMA6D,ZFP2,CASC3,SH3GL3,FBXO11,FHOD3,R3HDM2,ST6GAL1,FAM81A,PREX2,SLC2A5,SLC8A1,ARHGEF40,SMARCC2,FAM219A,DOP1A,ZC3H13,SPTAN1,ZBTB43,DDN,NFASC,CLSTN2,ITPRID2,SSTR1,NEK4,CEP68,KANK1,JMJD6,TMEM150C,ASTN2,CAMTA1,ADGRL3,TPCN2,FAM189A1,SIK3,ZNF106,AKTIP,MTMR14,HEY1,R3HDM1,WBP2,ZNF346,RUNDC3B,AMACR,DCBLD1,RUSC1,KCNE5,TSC1,CLHC1,GORASP1,UGT8,PLPPR2,TBC1D15,RICTOR,CFAP298,ZIC1,ZNF711,TRIM9,ATP6V0E2,NDRG4,FTSJ1,ZFAND5,EMSY,PPP1R3F,RGS7BP,KAT6A,SMIM8,FAM219B,ADAMTSL3,NHSL1,FXR1" MicroRNA hsa-miR-627:mirSVR_lowEffct hsa-miR-627:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-77 7.98E-74 1.06E-76 9.76E-76 223 1413 "ABR,EMILIN3,NCKAP5,KLHL32,TMEM132B,ADD2,BRAP,PWWP2A,SLC24A4,SPOP,TNRC6C,LGR5,MARCH3,EIF4G3,ATP1B3,DPY19L3,BBS2,CFLAR,BMPR1B,BAIAP3,LDLRAD4,CACNB4,CAMK2G,VXN,RUNX1T1,MTMR7,CDH2,TIGD7,SLIT2,TPP1,FAM19A5,QKI,MAP4K4,LY86,CNTFR,FAM149A,COL4A5,TBPL1,C1QL2,SNCAIP,CSF2RA,CNTNAP2,PPP1R16B,KIAA0040,UBXN2A,RUBCN,DOCK4,ARHGAP32,KATNAL2,ARHGAP24,DGKG,AIF1L,ARMCX4,YTHDC1,HEPH,KIAA0753,RUSC2,LYPD1,SPOCK3,FAM107B,KIF19,SEC16A,EXOG,DYNC1I1,CDON,DTNA,EBF1,EDNRA,EDNRB,FRY,YAF2,APH1A,KMT5B,GOLGA7,TENM1,STARD3NL,USPL1,EPB41L2,RASGRP2,ENPP6,STX2,ZNF549,ETV1,VPS26C,ZNF589,GORAB,OLFM1,FLYWCH1,SYT3,C2orf88,JKAMP,UFM1,KHDRBS3,CELF1,HHIPL1,MEGF10,GALC,ZNF559,DISC1,SRRM4,KIAA1841,ALDH1L1,PCDH17,TCERG1,LILRB4,GPD2,GRIN2C,GRM2,PRDM5,ZBTB45,GUCY1B1,ATOH8,RASSF8,FRMD5,CPT1C,ZNF546,LRRCC1,KCNJ5,KCNK3,CREG2,STXBP5,LAMA2,HECTD2,NCOA7,LSS,PIK3AP1,SHC3,MIA2,MSR1,MYO7A,ZC3H12B,NDP,NF1,NFE2L2,NPTX1,SMIM11A,P2RX7,PCSK1,PCSK5,PDE4D,PDPK1,XRN1,KCTD15,JAKMIP1,PMP22,MAPKAP1,MAGEL2,POLG,PKIA,TMEM104,PIGG,TMEM260,PTPRB,SUSD4,ROGDI,RASGRF2,ZMAT4,REV3L,ERI2,MORC4,UBR7,SLC25A36,RIC8B,PBRM1,RNASEL,ARMC5,ROBO2,CCDC102B,MRAP2,SPIN3,ATP8B4,FBXO11,ST6GAL1,NLGN1,ANKRD6,FAM214B,CCDC88A,SLC12A2,ELMO2,BTBD7,ZNF667,BDP1,SOX11,NMNAT2,UHRF1BP1L,TSPYL2,NKAIN2,ZSCAN29,DIP2A,PHLDB1,KANK1,STXBP1,RHBDL3,VPS13A,ANKRD12,AGTPBP1,SATB2,TPCN2,PHF24,FAM189A1,HIF3A,AP4E1,FAM124A,BEX4,RIMBP2,RASD2,DOK6,SYNPO2,AMACR,VLDLR,TBC1D15,KLC2,LYPD6,ZBTB38,TMEM198,ANKS1B,INTS3,EMSY,DNALI1,STOX2,ADAMTS9,ST8SIA2,FAM198A" MicroRNA hsa-miR-4256:mirSVR_lowEffct hsa-miR-4256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-77 9.71E-74 1.29E-76 1.19E-75 212 1282 "ASPHD1,KLHL32,GALNT16,ADD2,WDR35,OSBPL8,FAM135A,SYT13,AMPD3,ZFAT,CDC42BPA,CCDC146,PARG,EPB41L5,PHYHD1,BCAS1,IGDCC4,MARK4,BBS2,RGS11,DNAJC27-AS1,ST3GAL5,CASTOR3,THSD7A,CALM1,KALRN,CBR1,CLDN10,USP6,LRBA,LOC730101,DLGAP2,CHGB,SOCS6,ARHGAP22,NRXN3,FBXO7,SLC35F1,CSF1R,RIMS4,APPL1,PHF14,DOCK4,EARS2,SPOCK2,KIAA0753,SPOCK3,HS3ST2,USP3,DOCK2,ACOT8,DTNA,DNAJB6,ABCC5,E2F5,SEZ6L2,EDN1,PHC2,HIPK3,SEMA3D,KLHL5,TMTC1,YAF2,PHF20L1,TMEM132E,AASS,TENM1,PLEKHA1,EPB41,RASL12,F5,TAOK3,MED12L,OLFM1,FGFR1,SEC23B,SYNCRIP,SEMA4D,TMEM107,UFM1,ATP2C1,ZNF605,DLL3,ZMAT1,MEGF10,CHL1,FAM120B,B4GALNT1,ZNF274,LRRC37A6P,ALDH1L1,NFU1,MMADHC,GFRA2,DBF4,SPIN1,ZNF638,HTATSF1,GNG4,LILRB4,GPD1,STON1,GPR34,GRIA2,IRAK3,GABARAPL2,SYNPO,SMAP1,GAREM2,SCIN,KCNN2,IPO5,KTN1,SYTL4,LSS,MAP4,MBP,N6AMT1,MXI1,MYT1,ZC3H12B,CCDC13,NF1,ALDH1L2,NOVA1,SLC11A2,SMIM11A,TBC1D25,PDCD2,PDE4D,PDE1B,SLC10A4,PFKFB3,PFKFB4,SEMA5B,NLE1,PRIMPOL,RETREG2,FA2H,POLG,SH3KBP1,POU6F1,PPM1B,PPP1R1A,PKIA,PRKCB,MAPK4,HYDIN,WBP1L,PIGG,CNTLN,STK32A,PTPRB,PTPRE,ACSS3,RASGRF2,REV3L,RNASE1,ROBO2,EPHA10,FBXW7,CCDC112,SCP2,ASAP3,HKDC1,AMBRA1,R3HDM2,ST6GAL1,SLC14A1,SMARCA4,USP33,FNBP1,TEX2,PEG10,TSPYL2,TROVE2,MPRIP,ELOVL4,SYP,TACC1,MTCL1,DNMBP,TCF4,ZFP90,CUX2,USP22,PCDHB9,SIK3,RASD2,NPL,SMUG1,ELP5,DCBLD1,TSC1,FAM155A,UGT8,FLRT2,VLDLR,LAT2,ZBTB14,ZIC1,ZNF540,AGMO,ZBTB38,TMEM237,POLR3H,PRDM10,RNF103,HPS4,MDH1B,FIP1L1,FAM47E" MicroRNA hsa-miR-151-3p:mirSVR_lowEffct hsa-miR-151-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-77 1.26E-73 1.67E-76 1.54E-75 207 1225 "ABHD6,NDRG3,PLEKHH1,ADRB2,BEND6,TBC1D14,CC2D2A,AK2,GPRASP2,AMPD2,FGD2,ZNF583,ADGRB3,LINC00847,BMPR1B,DST,SYNJ1,SYNJ2,FUBP1,CALB1,KALRN,PTBP2,SPAG9,CLDN10,SEPT7,LRRFIP1,CDO1,CCPG1,CHN2,TPP1,CLTC,ABCG2,QKI,MAP4K4,FHL5,ABI3BP,RCHY1,MYRIP,ZNF521,CDC42BPB,SEC24C,SUSD5,IPCEF1,PLXNA4,FAM169A,SLITRK5,PPP1R16B,ERC2,GREB1,USP6NL,CCDC144A,HDAC9,ARHGAP32,TBC1D5,GIT2,ZBTB24,ELMO1,FBXL5,ZC3H11A,RHOBTB1,DMD,CPEB2,DOCK2,HIPK3,PHF20L1,TENM1,PLEKHA1,LRRC17,GMPR2,MRVI1,CORO2B,CEP78,FKTN,GTF2IRD2,FGF12,TMEM164,POLK,UBE2E3,HPCAL4,IP6K2,COQ5,UFM1,ATP6V1H,KHDRBS3,CGREF1,CSPG5,MEGF11,MEGF10,SIGLEC8,MSTN,GGTA1P,GLYR1,RAB30,TNRC6A,KIAA1958,PRUNE2,GRB10,GRM8,FAM19A2,MAP4K5,AGBL5,IRF8,MSL1,ZNF678,INPP5B,NME9,ITGA7,STXBP5,LAMA2,SYTL4,MAP2,MEF2C,MEIS2,BLOC1S2,CNOT4,SMIM11A,FAM225B,PAX6,PDE1C,PDE4D,FAM98B,NALCN,PIK3C2A,ZNF655,GPSM2,STRN3,ING3,PPP3CA,PPP3CC,CEP41,MASP1,SNRK,ANKHD1,EML5,PTPRH,TUG1,RADX,RET,FIGN,RFX3,UBR7,RGS3,RGS12,EXD2,ARMH4,ZNF671,ATP8B4,ATAT1,ATXN7,CASC3,GALNT10,ASAP3,CHD9,ANKRD6,FAM214B,SLC8A1,SLC12A4,NAPB,BTBD7,SNRPN,FAM219A,DOP1A,BDP1,UHRF1BP1L,CDK19,SPART,ATP10B,NXT2,ZSCAN29,RGL1,SEPT3,STXBP1,ADAMTS17,COBL,FBXW11,TPCN2,CLASP1,DOCK9,PHF24,TNS2,FAM200B,SIRT1,KAT6B,PIK3R5,ELP5,TRPS1,RUSC1,TSC1,FAM155A,UGT8,BCL2L13,CCDC14,VLDLR,XRCC4,LGI4,ZNF540,ATP6V0E2,ZBTB38,AMZ1,EMSY,ADAMTS9,MDH1B,NAV3,TRIM16L,GAN,FAM198A,JPH3" MicroRNA hsa-miR-1298:mirSVR_lowEffct hsa-miR-1298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.24E-77 2.37E-73 3.14E-76 2.89E-75 191 1047 "RALGAPA1,ACADM,PTCHD1,OSBPL6,FAM135A,AMPD3,LRCH2,PKP4,PARG,APC,BCAS1,ARNTL,RGS20,ZBTB10,ATP1B3,ATP2B2,ZNF583,RNF182,ADAM23,RGS9,BID,DST,ARHGEF7,JAZF1,SGCE,C5,CA8,RUNX1T1,CBR1,NOG,RCBTB2,CHN2,EPS15L1,NRXN3,NGEF,QKI,AKAP7,AKAP6,COL4A5,IGDCC3,CREM,VCAN,CTH,RIMS2,CCDC144A,CYBB,DOCK4,KCTD8,PITPNC1,SPOCK3,DLX1,RAB39B,DMD,DPH1,DTNA,EDN3,HIPK3,EGFR,EGR3,DLC1,CEP78,FCGR3A,SEC24B,SUCO,ANKFY1,SLC37A3,EFCAB2,TMEM107,STAU2,IQGAP2,NFU1,ADAM28,BRD8,TTBK1,HPGDS,GLI2,LUZP2,FERMT2,ADGRA3,FUT10,GPR37,GRB10,PRDM5,RABL2A,SOX21,PSIP1,FRMD5,GABARAPL2,IRF8,MSL1,IGF1,ZIC5,RBPJ,IL12A,LINC00634,LIMS1,PAXBP1,ZNF667-AS1,MATN3,MEIS2,MEST,KCTD6,MMP16,SFR1,NEFH,NELL2,NF1,NOVA1,ETFRF1,GNG2,GPSM2,JAKMIP1,PLIN1,PPM1B,DIRAS2,KLK6,VPS13C,TMEM104,QRICH1,PTK2,STK32A,PTX3,TUG1,PID1,CEP97,FAT4,RBBP6,GAL3ST4,ZMAT4,REV3L,UBR7,DCUN1D2,GSTCD,ROBO1,NEK11,FBXW7,ADAL,RPS6KA2,ATAT1,NCBP3,TRAPPC13,RMI1,ZFP2,GALNT10,KIF21A,PPM1E,FNDC3A,NLGN1,WDR47,CCDC88A,CPEB4,SNRPN,ERC1,RBM26,TROVE2,ITPRID2,ZNF302,NKAIN2,KANK1,KLHL7,SYT1,MTCL1,ALG1,AGTPBP1,ZEB1,RPGRIP1L,PCDHA5,HIF3A,FAM200B,SIRT1,AP4E1,ACTR6,TRIO,TRPS1,EIF4ENIF1,UBE3A,PLEKHH2,VLDLR,ZNF32,TRIM9,LYPD6,REEP1,ANKS1B,EVI5,FIP1L1,FAM13C,AMN1,RNF170,ZDHHC20,FXR1,IFT88" MicroRNA hsa-miR-500b:mirSVR_lowEffct hsa-miR-500b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.38E-77 2.45E-73 3.24E-76 2.98E-75 238 1609 "KCNH8,ABR,ABHD6,NCKAP5,GALNT16,TMCC3,GALNT13,ESYT2,AP2A2,MTUS1,CC2D2A,ADGRF5,CEP126,LRCH2,EPB41L5,ARNTL,ZBTB10,TMEM108,CHID1,EIF4G3,ATP6V0A1,BACH1,BCHE,MIR9-3HG,PROM1,FUBP1,CA8,KALRN,CAMK2A,CBS,CCNH,RGN,MAGI1,NUMBL,MS4A7,B4GALT6,CLCN3,QKI,COL4A5,COX4I1,BAG4,MYRIP,ZNF521,SEC31B,C2CD2,HAPLN1,RUBCN,CCDC144A,DCAF8,MATR3,AIF1L,SV2B,GRIN3A,DMD,NR1D2,DTNA,DNAJB6,E2F5,E2F6,FCF1,FRY,PHF20L1,MBNL2,KMT5B,AASS,PLEKHA1,PCOLCE2,PAN3,RCAN2,ERCC2,ANKMY1,MRVI1,F5,REEP2,ARMCX1,RACK1,CEP78,SEC24B,FER,FGF1,FGF12,POLK,UBE2E3,MEX3B,PCYOX1,VTI1B,SYNCRIP,FLT1,C2orf88,WDR83,APOPT1,FAM49B,ATP6V1H,CELF1,MSANTD4,ZMAT1,DENND2A,IP6K3,DISC1,NEU3,GFRA2,MALT1,GLI2,ZNF638,GPR12,STMN2,GRIA2,PRDM5,RNF165,AP4S1,ATOH8,HAS2,ATXN2L,HNF4G,DHX35,MSL1,IDH3B,RBPJ,NIM1K,KTN1,LAMP2,NCOA7,MATN2,MBNL1,TM6SF1,LRP1B,MEIS1,KCTD6,MIA2,BLOC1S2,MYO7A,NEFH,NEK1,NFE2L2,NOVA1,SLC11A2,NUCB2,GLIPR1L2,CNTN3,DPY19L2P2,PDE3A,GPR173,SERPINI1,FAM218A,KCTD15,PLXNB1,ING3,RETREG2,DRAM2,DCHS2,SAMD9,ZIK1,PTPRG,TMEM145,TUG1,PPP2R3C,FAM66C,SH3TC2,ENOX1,OXR1,RASGRF2,RBBP8,KHDRBS2,TRIM68,RET,FIGN,RFX3,RIC8B,NEK11,ZC3H14,TCP11L1,LRRK2,MEG3,ABCA11P,SCP2,SCAF8,KIF21A,SH3GL3,FERMT1,DZIP1,PKNOX2,BTBD7,CPEB4,IFT122,CABCOCO1,BDP1,SP4,MYCBP2,DBNDD2,SPTAN1,CDK19,TSPYL2,SPART,POGZ,THSD1,ELOVL4,ADHFE1,ARHGEF9,VPS13A,SYN1,SYN2,CAMTA1,DMXL2,SATB2,RPGRIP1L,FAM200B,PMS2CL,MTMR14,R3HDM1,C9orf85,WBP2,TRIO,TRPS1,UBE3A,BCL2L13,VAV1,RICTOR,XPO1,ZIC2,TRIM9,ATP6V0E2,TMEM237,ANKS1B,SMARCAD1,STOX2,RNF103,ADAMTS9,FAM47E,EPM2A,FAM13C,FZD3,HNRNPA3,MSRB3,KLHDC1,IFT88,NETO1,FAM198A,SPATA13" MicroRNA hsa-miR-3129:mirSVR_highEffct hsa-miR-3129:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.61E-77 2.58E-73 3.40E-76 3.13E-75 198 1126 "RALGAPA1,KCNH8,KDM5D,MTUS1,KCTD16,HACE1,OSBPL8,TXNDC16,TAOK1,ALCAM,CEP126,ANK2,UPRT,SPTBN4,CADPS,ZBTB10,DPY19L3,NRP2,DST,SYNJ1,FUBP1,IL33,CA8,KALRN,NFS1,DCLK1,CDO1,CFL2,SRSF11,MS4A7,QKI,MAP4K4,FHL5,ARMC8,COL4A5,LETMD1,MYRIP,CPS1,FAM171B,RNF14,CSF1,OSBPL3,VAC14-AS1,PHF14,USP6NL,BOC,ARHGAP24,ZNF337,SNAP91,WDR20,FAM107B,DTNA,ECM2,EBF1,EDN1,EDNRB,FAM13A,AASS,CALCRL,DCTN4,LRRC17,CEP85L,SH3YL1,FCGR3A,ZSCAN30,GORAB,MED12L,FGF11,SPSB4,PSD2,POMT1,TMEM107,HVCN1,UFM1,PDLIM5,STAU2,MSANTD4,HHIPL1,OGA,CHL1,ZNF559,TUBGCP4,TUBA8,COPS8,DBF4,TOX3,ZNF638,GPD2,LPAR4,GPR37,ZHX1,HNMT,MSL1,IFI16,SCIN,ZNF678,KCNH2,KCNN2,KIF2A,KIF5A,KTN1,HECTD2,NCOA7,ZNF667-AS1,MBNL1,MEIS2,SRSF12,MITF,XRRA1,ADAM22,NRBP2,NCAM2,NF1,NOVA1,DNHD1,SLC11A2,PDE4A,PDE4B,PLIN1,PMP22,PPP2R2B,PPP2R5E,KANSL1,CEP41,PRKCB,DCHS2,CNTLN,BDNF-AS,PTPRE,C1orf109,MARCH1,CEP97,RADX,KHDRBS2,RGS4,PRIMA1,RNASEL,RORB,CCDC102B,ZC3H14,PTGR2,CLIP1,SCN8A,SCP2,ZFP30,WDR47,CPEB4,SMARCC2,ANKRD36,LMBRD1,SNRPN,USP33,DOK5,KDM3A,SP2,LMO3,CLASP2,SS18,NUDT10,PLCB1,SYPL1,DMXL2,USP32P1,AP4E1,MTMR14,SYNPO2,SGK3,TUBB1,BCL2L13,VLDLR,CLDND1,XPO1,XRCC4,ZNF711,MICU3,KCNT2,ATP6V0E2,ZNF138,ZNF177,SPIRE1,SMARCAD1,DHX33,TMEM178A,KCNAB1,PDSS2,RGS7BP,UBE3B,KAT6A,SMIM8,CASC15,ADAMTSL3,JMJD1C,FXR1,IFT88,DPF3,GAN,CPNE4,FAM198A" MicroRNA hsa-miR-219-2-3p:mirSVR_highEffct hsa-miR-219-2-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-77 2.67E-73 3.51E-76 3.23E-75 200 1149 "ADCY6,INTS2,HACE1,KIAA1324,C1QTNF3,AMPH,LRCH2,APOC2,SPTBN4,CDK13,NUMB,RNF182,DST,SYNJ1,ST3GAL5,ARHGEF7,MTMR2,CA8,PTBP2,CAMK2G,CAST,ZNF501,CLDN10,LDB2,DGKI,LRBA,MAGI1,TIGD7,RCBTB2,CHN2,PPT2,COL4A5,ABI3BP,AHCTF1,MYRIP,ZFP28,FAM171B,AKAP12,HAPLN1,GDA,SEC24C,ARHGEF10,APPL1,GREB1,RIMS2,DOCK4,KATNAL2,ZFYVE16,KIAA0586,SV2B,SPOCK3,DNAH9,PDCD6IP,RCAN1,EDN1,EDNRB,ANKRD46,PHF20L1,VPS13B,GPHN,RPS6KC1,ST3GAL6,ZNF589,FER,FGF1,SYNCRIP,ANKFY1,SLC37A3,SMC2,PDLIM5,TPK1,CAMKK2,ZNF605,CELF1,STAU2,MSANTD4,DOT1L,ABLIM2,GALC,MTHFD2,ZNF559,IGSF5,ALDH1L1,GGTA1P,GHR,BRD8,TXNL4A,GLYR1,GNAL,FERMT2,GPT2,PRUNE2,PCLO,DIDO1,ZNF496,COQ10A,AP4S1,MAN1B1,SMAP1,IFI16,RBPJ,IL6ST,KCND1,IPO5,CYP27C1,ZFYVE27,MAP2,MARK1,LYPLAL1,MEIS2,AFDN,ZNF680,MSR1,MXI1,MYCN,P2RY13,NDP,DPY19L2P2,SLC10A4,GPR173,PLCL1,PCDH18,TRHDE,MAPKAP1,PRKACB,PKIA,DCHS2,BDNF-AS,MTMR10,TMEM260,PEX2,USP47,RAD17,NWD1,RASGRF1,KHDRBS2,RET,SLC25A36,RNASEL,ROBO1,TRAPPC13,DGLUCY,ATXN2,SCN8A,GALNT10,CPEB3,FNDC3A,NLGN1,FAM81A,BTBD3,EPN2,SEPHS1,SLC12A2,NAPB,ATF7IP,SNAP25,ZNF415,SNRPN,UNC5B,CLASP2,SSTR2,TTBK2,SYT1,ANKRD12,MCF2L,ATMIN,RPGRIP1L,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AP4E1,SLC44A1,TIAM1,BHLHB9,CSMD1,RUNDC3B,NEIL2,CLHC1,UGT8,TBC1D15,ZNF781,ZBTB14,ZNF540,TCEAL7,ZNF184,DHX33,DNALI1,STOX2,PRDM10,PLSCR4,DOCK8,HNRNPA3,PHTF2,ACTR3B" MicroRNA hsa-miR-148b*:mirSVR_highEffct hsa-miR-148b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-77 2.67E-73 3.51E-76 3.23E-75 200 1149 "C3orf14,FMNL2,TMCC3,HECW2,KIAA1324,OSBPL8,CC2D2A,PCDH10,APC,USP37,MARCH3,ATP2A2,RNF182,DPY19L3,TTLL9,CFLAR,DST,JAZF1,PTBP2,SLC25A14,CAST,RUNX1T1,AP4M1,B4GALT6,SLIT2,SUMF2,RCHY1,CLIP3,SNCAIP,CSF2RA,PUM1,ZSCAN23,EARS2,FBXL5,GSDME,DDX46,SACS,DLX1,USP3,NR1D2,CPEB2,DOCK2,DPYSL2,PDCD6IP,EDNRB,FRY,FAM13A,COPS4,PLEKHA1,EPHB1,GPHN,ERCC2,EYA1,FCGR1B,FCGR3A,SEC24B,FGF12,FGF13,FGFR1,FHL1,POLK,VTI1B,ATP13A4,SMC2,APOPT1,UFM1,KHDRBS3,AP4B1,GABRG2,DISC1,IGSF5,NEU3,GHR,KDM2B,HTATSF1,ZNF782,FUT10,IRAK3,RASSF8,UBE2QL1,FRMD5,HNMT,ZDHHC15,HSF2,SMAP1,EID2B,ZNF546,NKD1,SCIN,IL6ST,JAK2,KCND2,KIT,SYTL4,MAP4,MARK1,MAT2A,MEIS1,MEIS2,SRSF12,MIA2,AFDN,COL28A1,ADAM22,IDNK,NEFM,NF1,CNOT4,NPTX2,NRCAM,NUCB2,ETFRF1,NALCN,PIK3C2A,NLE1,PLCL1,SDK2,ING3,EPB41L4B,PPP2R5E,GRAMD1C,RELN,SNRK,WDR25,CNTLN,ANKHD1,ELOVL2,PTPRD,MARCH1,CEP97,ZDHHC14,ERI2,RIC8B,CCDC82,SETD5,EXD2,CARF,ROBO1,CCDC102B,BAALC,ZC3H14,LRRK2,KCNIP1,FAM192A,TNFRSF19,TRA2B,KIF16B,ST6GAL1,CNKSR2,NLGN1,KBTBD4,LIMCH1,SNCA,TRERF1,KDM3A,SP4,HECW1,KDM4C,TROVE2,ELOVL4,KANK1,SULF2,STXBP1,PRRC2C,VPS13A,DNAJC9,SYT1,COBL,ANKRD28,TBCEL,SATB2,ZFP90,ZEB1,TRIM2,TCF12,FRYL,RNF216P1,SLC44A1,NR2E1,FAM124A,CSMD1,NPL,KCNE5,TSC1,SSBP2,UBE3A,PLEKHH2,P2RY12,GUSBP1,TRIM9,ZNF177,EVI5,TMEM178A,VPS35L,FAM13C,PHTF2,NLRP3,NHSL1,NETO1,SENP7" MicroRNA hsa-miR-200c:PITA hsa-miR-200c:PITA_TOP PITA 5.40E-77 3.02E-73 3.97E-76 3.65E-75 169 815 "SYS1,XKR4,USP31,PTCHD1,SLC24A4,GPRASP2,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,SLC4A4,SYNJ1,FUBP1,JAZF1,SGCE,CACNB4,THSD7A,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,FAM19A5,MAP4K4,CNN3,CNTFR,CRHBP,NCOR2,CSNK1G3,PHACTR3,PLCXD3,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,KCTD8,IP6K1,GIT2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,PAN3,ERBB4,TAOK3,DLC1,AMOTL2,PRKAG2,MEX3B,FOXF2,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,SESN1,PPARGC1A,COPS8,FERMT2,CIT,PSIP1,MAP4K5,BACH2,MIER3,HLF,NEGR1,AGFG1,KCND2,NCOA7,MAP2,LRP1B,MYCN,MYT1,ZC3H12B,NFYA,CNOT4,NOVA1,NPTX1,GPR137C,PCDH8,PDPK1,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,PPP2R2C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,PTPN13,OXR1,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,PUM2,FRYL,ZFPM2,ERCC6L2,LRRC8A,NR2C2,VLDLR,TBC1D15,WIPF1,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,PHTF2,FXR1,GAN,SENP7" MicroRNA hsa-miR-200b:PITA hsa-miR-200b:PITA_TOP PITA 5.40E-77 3.02E-73 3.97E-76 3.65E-75 169 815 "SYS1,XKR4,USP31,PTCHD1,SLC24A4,GPRASP2,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,SLC4A4,SYNJ1,FUBP1,JAZF1,SGCE,CACNB4,THSD7A,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,FAM19A5,MAP4K4,CNN3,CNTFR,CRHBP,NCOR2,CSNK1G3,PHACTR3,PLCXD3,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,KCTD8,IP6K1,GIT2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,PAN3,ERBB4,TAOK3,DLC1,AMOTL2,PRKAG2,MEX3B,FOXF2,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,SESN1,PPARGC1A,COPS8,FERMT2,CIT,PSIP1,MAP4K5,BACH2,MIER3,HLF,NEGR1,AGFG1,KCND2,NCOA7,MAP2,LRP1B,MYCN,MYT1,ZC3H12B,NFYA,CNOT4,NOVA1,NPTX1,GPR137C,PCDH8,PDPK1,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,PPP2R2C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,PTPN13,OXR1,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,PUM2,FRYL,ZFPM2,ERCC6L2,LRRC8A,NR2C2,VLDLR,TBC1D15,WIPF1,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,PHTF2,FXR1,GAN,SENP7" MicroRNA hsa-miR-217:mirSVR_highEffct hsa-miR-217:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.46E-77 3.06E-73 4.01E-76 3.69E-75 211 1278 "CLK4,GALNT13,INTS2,MTUS1,TXNDC16,CC2D2A,ABCD2,ALK,AMPD3,OGT,CDC42BPA,PKP4,UPRT,SFMBT2,ZFYVE28,CCAR2,SLC2A11,N4BP2L1,ATP6V0A1,ADGRB3,ZNF599,DST,CALM1,METTL6,LRBA,SEPT7,SRSF11,CHN2,NDST3,AKAP6,AHCTF1,ZFP28,FAM171B,RBM39,AKAP12,CS,CSF1R,LRRC3B,PLXNA4,PHF14,ZSCAN23,USP6NL,CCDC144A,KIAA0408,DOCK4,HDAC9,KIAA0586,KCTD8,BRINP1,MYEF2,KIAA0319,ALKBH8,SPOCK3,CHRDL1,GOLT1B,EDIL3,EDNRA,YAF2,SUGP2,EXTL2,ADGRV1,ACSL4,CORO2B,DLC1,CHST15,SLC9B2,FGF11,FOXO3,ATP13A4,NOP56,SMC2,FAM49B,ZNF605,SARAF,GALC,SIGLEC8,NEU3,BRD8,RAB30,FERMT2,ADGRA3,CNTRL,GRIA2,HAS2,MIER3,HLF,HNF4G,NEGR1,IL6ST,KCND2,KCNJ16,STXBP5,LAMP2,HECTD2,NCOA7,SMAD9,MAP2,CHIC1,TM6SF1,POC1B,ZNF680,ZNF92,MYO9A,NF1,NME4,NOVA1,NRCAM,NUCB2,SETD4,CLDN11,GPR137C,CNTN3,PCDH8,PCDH9,PDE4B,GPR85,NALCN,PURG,TRHDE,PPM1B,SLC26A11,GDPD1,SAMD9,VPS13C,PTCH1,TMEM260,MARCH1,FAT4,RAP1GDS1,ZNF493,GTDC1,FIGN,RFX3,RGS12,ZFHX4,CCDC82,CARF,RORB,NEK11,ARMH4,ATP8B4,ABCA11P,ATAT1,RTN1,ZNF568,SEMA6D,SATB1,SCP2,SUPT20H,HSPA4L,SGK1,FBXO11,FHOD3,BTBD3,WDR47,SEPHS1,SLC14A1,BTBD7,TET1,GKAP1,LIMCH1,KIF13A,SNRPN,KDM4C,ZNF423,LHPP,PBLD,ITPRID2,ZNF302,SEPT8,CEP68,TTBK2,ZC3H4,NUDT10,EXOC7,ADGRL3,TBCEL,FBXW11,ATMIN,ZEB1,RPGRIP1L,SYNE1,SLC35G2,SIRT1,ZFPM2,ASXL3,TLR4,SSBP2,TUBB1,VSNL1,RICTOR,PCDH20,ZBTB14,ZNF711,ZNF708,ZNF19,MICU3,ZNF45,DHX33,INTS3,STOX2,PRDM8,TMEM178A,NAV3,PDSS2,EPM2A,HNRNPA3,FBXO36,FXR1,GAN,SENP7" MicroRNA hsa-miR-3144-3p:mirSVR_lowEffct hsa-miR-3144-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.61E-77 3.14E-73 4.11E-76 3.78E-75 202 1173 "ACADM,XKR4,FMNL2,ADD1,ESYT2,OSBPL1A,ABCD2,ARHGAP20,FAM135A,MAP4K3,PARG,NUMB,ATP2B2,BBS2,SEC11C,BCHE,KSR1,BMP7,GPC2,HAP1,KYAT1,LDB2,LRRFIP1,MAGI1,ZFP28,PREPL,HAPLN1,SNCAIP,VAC14-AS1,APPL1,PHF14,DCAF4,CCDC144A,CYBB,DOCK4,HDAC9,TCAF1,RIPOR2,ZFYVE16,MATR3,KIAA0586,KCTD8,DGKG,YTHDC1,ZNF804A,TIAM2,KIAA0319,ZC3H11A,RHOBTB1,SNAP91,CASP8AP2,RCAN1,DTNA,ECM2,HIPK3,FCF1,RASGRP1,PHF20L1,APH1A,MBNL2,EIF5,MRPL10,ZNF585B,SH3YL1,TAOK3,CEP78,FECH,HPCAL4,SYNCRIP,FOLH1,C2orf88,PDLIM5,ATP2C1,ZNF605,ST6GALNAC3,SARAF,ABLIM2,DISC1,MSTN,ADAM28,ADGRA3,TDRKH,GRB10,PRDM5,CIT,RNF165,RASSF8,ICA1,ZIC5,RBPJ,METTL21A,STXBP5,LIMS1,PIK3AP1,CHIC1,SRSF12,MEST,KCTD6,MIA2,POC1B,MMP16,SAMD5,MYO5A,NF1,DNHD1,NTRK2,LOC100128398,PCSK1,PRTG,PDE1C,GPR85,GNG2,SERPINI1,ZNF655,SNX10,MAGEL2,EPB41L4B,HYDIN,SAMD9,TMEM104,CNTLN,ANKHD1,MTMR10,PTPRB,C1orf109,ZNF493,REV3L,SLC25A36,NUDT11,CCDC82,TMLHE,ALG9,BAALC,SPIN3,MCMBP,RMI1,SCN2B,TNFRSF19,PEAR1,SCAF8,KIF21A,PPM1E,KIF16B,SHMT2,FBXO11,FNDC3A,R3HDM2,SEC31A,WDR37,FAM81A,PPP4R3A,SLC12A2,ELMO2,ANKRD36,LIMCH1,MBD5,SNRPN,SP2,CLASP2,POGZ,SAMSN1,ZSCAN29,ELOVL4,CEP68,SYNE2,VPS13A,PJA1,FAM208A,ALG1,FBXW11,TRIM2,TCF12,FRYL,CCDC173,DICER1,ITGB3BP,GPR161,ZNF106,AKTIP,ERCC6L2,TPM1,C9orf85,RGMB,ELP5,SSBP2,FAM155A,ZBTB14,ZNF74,LYPD6,POLR3H,ANKS1B,CADM2,SLC38A1,EVI5,STOX2,NAV3,URM1,HNRNPA3,PHTF2,JMJD1C,SNX14,NETO2" MicroRNA hsa-miR-3137:mirSVR_lowEffct hsa-miR-3137:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.66E-77 3.73E-73 4.87E-76 4.49E-75 222 1412 "KDM5D,ZNF608,RTL9,TXNDC16,CC2D2A,C1QTNF3,ALCAM,ARHGAP20,PCDH10,UNC79,OGT,FGD2,FAM131A,TNRC6C,AQP6,CDK10,CDK13,PDE8B,MARK4,NCOA1,TMEM108,N4BP2L1,BACH1,ADGRB3,BCHE,ST3GAL5,SCAPER,MTMR3,KALRN,PTBP2,CAMK2G,LDB2,CD38,ASIC3,EPS15L1,RAB28,ABCG2,CNN3,IQCK,PCYT1B,ARMC8,COX4I1,CLOCK,RNF14,CS,SNCAIP,CSNK1G3,VAC14-AS1,KIAA0040,MYADM,HDAC4,EARS2,ZNF337,DAPK1,PITPNC1,YTHDC1,ELMSAN1,HEPH,PDCD6IP,DNAJB6,E2F5,E2F6,YAF2,PHF20L1,KMT5B,RASA4,EIF4G2,EIF5,TENM1,VPS13B,COQ7,SPEG,ETV1,DNAJC27,RASL12,NRN1,ARMCX1,PTK2B,SCML2,MED12L,FGFR1,AMOTL2,POLK,VTI1B,NELFCD,TMEM175,HVCN1,TRIM16,CELF1,AP4B1,MEGF11,GABRA3,IQGAP2,ACSS1,AHDC1,GHR,ZNF276,TCERG1,DBF4,TOX3,RAB40B,C1QL4,CLASRP,COQ10A,AP4S1,PSIP1,MIER3,HMGCR,ZDHHC15,NEGR1,AGFG1,DHX35,KNDC1,INPP5B,KCNB1,KCNJ16,LAMP2,STMN1,LMO2,MBD1,MEST,MMP16,NRBP2,MYO9A,RTL5,ZNF862,SLC11A2,NRCAM,NTRK2,NTRK3,LOC100128398,OPRL1,P2RX7,CNTN3,PDCD2,PDE4D,ENPP2,PFKFB2,OLA1,NALCN,STRN3,MAGEL2,SEPT4,FSD1,PPM1B,KANSL1,MAPK10,GDPD1,CNNM2,CYBC1,QRICH1,TMEM260,PTPRG,TUG1,FAM66C,RASGRF2,DPF2,RFX2,PRIMA1,SLC25A36,RIC8B,ZNF532,CYB561D1,RPL15,FBXW7,BAALC,ZC3H14,RXRA,SALL1,SATB1,GALNT10,TRA2B,SCAF8,SGK1,ZFP30,CPEB3,SHC4,FNDC3A,BTBD3,WDR47,SEPHS1,ARHGEF40,ELMO2,INAVA,ZSWIM8,SP4,TSPYL2,SEPT8,STAC2,JMJD6,SYN2,TBL1X,NAT16,SIRT1,ITGB3BP,TMPO,RIMBP2,PIK3R5,TPM1,NR2C2,TRO,CLHC1,HIRA,TUBB1,UGT8,OSBP2,CCDC14,KCNT2,SLC30A4,PRTFDC1,TRIM16L,RGS7BP,FZD3,DOCK8,CASC15,ACTR3B,ADAMTSL3,ADAMTS10,ZDHHC20,SOCS4,FAM198A,JPH3" MicroRNA hsa-miR-193b:mirSVR_lowEffct hsa-miR-193b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.02E-77 3.93E-73 5.13E-76 4.72E-75 203 1186 "KCNH8,ACADM,ASIC1,ACHE,CLK4,NCKAP5,ADCY6,ADD1,PWWP2A,PTCHD1,SLC24A4,AP2A2,PCDH10,UNC79,APC,VAT1L,BCAS1,TNRC6C,CDK10,SEMA4G,CASK,ZSCAN18,EIF4G3,DPY19L3,SYNJ1,SYNJ2,JAZF1,CAST,P2RX6,LRBA,EVI5L,NOG,UBE2L6,CACNA2D2,TAOK2,EPS15L1,NRXN3,CLTC,ARHGEF6,AKAP6,TOGARAM2,NCOR1,CST3,PLXNA4,PPP1R16B,RUBCN,FAM131B,TM9SF4,ARMCX2,RUSC2,GUCD1,MTX3,NYAP1,DOCK2,MAMLD1,DNAJB6,ABCC5,EDN1,HEYL,KMT5B,GOLGA7,ASB3,EIF4G2,ETV1,SIRPB1,ADGRV1,F5,SCML2,FCGRT,OLFM1,ANKFY1,PSD2,EFCAB2,GABBR1,TRAF3IP2,ZNF274,ERAP1,CRCP,TCERG1,STARD3,GRIN2C,PRDM5,LINC01089,AP4S1,MAP4K5,PADI2,ZHX1,MIER3,SMAP1,ICA1,MSL1,ZNF546,FAM69A,INPP5B,ITGAM,JAK2,KCNK3,KIT,CAMK2N2,ASPRV1,ZFYVE27,MGAT3,MMP16,ZNF680,RTL5,HNRNPM,NNAT,VWA2,DNHD1,OGG1,PCDH9,PDE4D,PDPK1,NALCN,CCSER2,NLE1,FAM216A,PLCB2,PNMA3,RETREG2,EPB41L4B,POU6F1,TATDN3,CCDC144B,PRKACB,GRAMD1C,SNRK,TMEM104,PTCH1,PTK2,TMEM260,PTPRE,PTPRG,PTX3,CEP97,FAM66C,TRIM68,SLC25A36,PBRM1,RNASEL,RNH1,GSTCD,KIRREL1,ROBO2,ATP8B4,TCP11L1,CLIP1,SATB1,GALNT10,SHMT2,NLGN1,SEC31A,CCDC88A,ATF7IP,LIMCH1,PDZRN3,USP33,DOP1A,ZSWIM8,HECW1,UHRF1BP1L,TSPYL2,DDN,NFASC,CLASP2,CLSTN2,SS18,ZSCAN29,SEPT8,KANK1,NSFL1C,SYN1,TMEM150C,COBL,TAF6,SMG6,TCF4,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TK2,LRRC8A,NPL,TPM2,ZNF346,AMACR,TRO,KCNE5,VLDLR,CLIP2,CRB2,NT5M,PRDM8,RNF103,NAV3,DOCK8,FXR1" MicroRNA hsa-miR-499-5p:mirSVR_highEffct hsa-miR-499-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.71E-77 4.87E-73 6.35E-76 5.85E-75 207 1234 "KCNH8,ACADM,CLK4,NCKAP5,PWWP2A,KIAA1211,HECW2,OSBPL1A,TXNDC16,ZNF578,HFM1,ABCD2,FAM135A,AMPD3,LRCH2,ASPA,CHRD,ZNF583,RNF182,DPY19L3,DST,MTMR2,IL33,PTBP2,PRC1,KRIT1,CD38,C1orf52,LRRFIP1,MAGI1,CDO1,CFL2,SOCS6,CHN2,MS4A7,NRXN3,QKI,HECTD1,COL4A5,SLC4A8,AHCTF1,NECTIN3,SLC35F1,PREPL,CREM,HAPLN1,RNF14,ANKRD44,OSBPL3,SUSD5,VCAN,SLITRK5,GREB1,CCDC144A,HDAC9,RIPOR2,ARHGAP24,KCTD8,GIT2,ELMSAN1,ZNF804A,ZBTB24,HEPH,MYEF2,DDX46,CHRDL1,USP3,DMTF1,DNM1L,GOLT1B,E2F5,EBF1,PHF20L1,KCTD3,EIF4G2,PLEKHA1,C8orf37,DCTN4,EPB41L2,SRRM1,RRAGB,EXTL2,F8,FGF12,SEMA4D,ATP13A4,C2orf88,SMC2,UFM1,PDLIM5,CAMKK2,ZNF605,KHDRBS3,STAU2,OGA,CHL1,KIAA1841,GDF9,PPARGC1A,ZNF276,DCLK2,TDRKH,STON1,PRDM5,UBE2QL1,TNFAIP8L3,SHISA6,MSL1,FAM95B1,ZNF181,RBPJ,HECTD2,NCOA7,MAP2,MARK1,MBNL1,MEIS1,SRSF12,KCTD6,ZC3H12B,NEFH,NEK1,NF1,NOVA1,CLDN11,ENPP2,PIK3C2A,GPSM2,SH3KBP1,DRAM2,PPP2R5E,PPP3CA,SLC26A11,PTCH1,TMEM260,SH3TC2,ZCWPW1,RASGRF1,KHDRBS2,RET,FIGN,CARF,ROBO2,FBXW7,SPIN3,ABCA11P,ZNF568,NCBP3,SEMA6D,ATXN2,SCN8A,SEC14L1,MRAS,TRA2B,CHD9,FNDC3A,FHOD3,SYBU,DZIP1,SEPHS1,SLC12A2,ATF7IP,ZKSCAN3,SMARCA4,RCOR3,LIMCH1,FAM126B,TRERF1,CDK19,TSPYL2,RBM26,TROVE2,ELOVL4,DIP2A,VPS13A,SYT1,ANKRD12,TCEA1,ZEB1,SYNE1,FRYL,ITGB3BP,NPL,TSC1,PRR18,FLRT2,BCL2L13,MTCH1,TBC1D15,ZNF711,ZNF708,ZNF19,KCNT2,ZNF540,CELF4,REEP1,MEIS3,SLC30A4,CADM2,STOX2,MDH1B,FZD3,ST7,FBXO36,TRAM2-AS1,NETO2,RNF146" MicroRNA hsa-miR-500*:mirSVR_lowEffct hsa-miR-500*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.59E-77 5.37E-73 6.99E-76 6.43E-75 210 1270 "NCKAP5,FMNL2,ADCY6,RNF157,ADD2,RNF150,BEND6,SLC24A4,MTUS1,OSBPL1A,TBC1D14,KIAA1324,OSBPL8,C1QTNF3,PCDH10,CCDC146,PHYHD1,BCAS1,TMEFF1,CDK13,STK33,NCOA1,SLC4A4,ATP2A2,DST,JAZF1,PTBP2,CBR1,ENTPD6,ZNF445,MAGI1,CRLF1,UBE2L6,NUMBL,RAB33A,TPP1,TMEM184B,SLC35F1,C2CD2,CRMP1,HINFP,ANKRD44,ABCG1,ARHGEF10,VCAN,VAC14-AS1,KIAA0040,ERC2,USP6NL,KIAA0408,GAPVD1,DCAF8,LONRF1,KIAA0586,BRINP1,GIT2,JAKMIP2,ZBTB24,MYEF2,RHOBTB1,WDR20,DYNC1I1,DMTF1,ACOT8,ARRDC4,DTNB,WDPCP,EDN3,CNNM1,SEMA3D,PHF20L1,GOLGA7,ZNF549,FAM198B,ZSCAN30,ZNF589,MED12L,GTF2IRD2,FHL1,FOXF2,AFF2,KHDRBS3,CELF1,NSG1,HHIPL1,MPP6,GABRB3,SIGLEC8,GCK,ALDH1L1,GGT5,PPARGC1A,ZNF276,GLYR1,PRUNE2,GRIA2,DIDO1,CLASRP,GSTT2,FAM107A,HLF,ELOVL5,SYNPO,HMGCL,MSL1,GAREM2,CDH20,KCNK3,STXBP5,MAN2A2,ZFYVE27,MITF,AFDN,COL28A1,PTOV1,MYO5A,ZC3H12B,NEFM,CCDC13,NF1,ALDH1L2,NTRK2,OXTR,PCSK5,CDK18,DUSP26,CCSER2,PKD1,FAM216A,STRN3,ING3,POU6F1,PPM1B,CCDC144B,PPP3CA,WBP1L,SNRK,CNTLN,PTPRD,PTPRG,PTPRH,CEP97,CCDC40,NWD1,RET,ERI2,RFX3,RIC8B,CYB561D1,CCDC25,ELP2,KIAA0895L,NCBP3,AP1AR,SCP2,SUPT20H,RASA3,FERMT1,CHD9,FNDC3A,ST6GAL1,DZIP1,SEPHS1,SLC14A1,ATF7IP,CDK5RAP2,SMARCD3,LIMCH1,SNRPN,PDZD2,SP4,MYCBP2,NFASC,SSTR1,ZC4H2,NKAIN2,ELOVL4,KANK1,ZC3H4,SYNE2,DNAJC9,SYP,C12orf76,KLHL4,ZFP90,CUX2,NAT16,OBSL1,SIRT1,ZFPM2,ITGB3BP,ACTR6,TPM2,CHST5,RGMB,SYNPO2,RUSC1,LINC00689,PLEKHH2,MTCH1,LAT2,ZNF708,LYPD6,ZNF189,DNALI1,SMIM8,HNRNPA3,FBXO36,FAM219B,IFT88" MicroRNA hsa-miR-363:mirSVR_highEffct hsa-miR-363:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.14E-76 6.35E-73 8.26E-76 7.60E-75 185 987 "SYN3,NCKAP5,TMCC3,KIAA1211,HECW2,TAOK1,C1QTNF3,MARCH4,FAM135A,PITPNM2,DPP10,ATP2A2,RNF182,DOCK11,ADAM23,ADGRB3,MPDZ,HCN2,SYNJ1,CACNA1I,KALRN,CAMK2A,MTMR7,CFL2,SOCS6,NRXN3,HECTD1,CNRIP1,FAM171B,CRHBP,ANKRD44,SOCS5,SLITRK5,ERC2,APPL1,CTH,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,PLPPR4,CDON,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,PHF20L1,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,POLK,SUCO,ATP13A4,SLC37A3,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,IQGAP2,GHR,SPIN1,GLYR1,FERMT2,GPD2,GPR12,TPPP,DIDO1,HAS2,MIER3,ELOVL5,HNMT,MSL1,RBPJ,SLC6A17,C2CD4C,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MN1,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,DNHD1,SMIM11A,CLDN11,P2RX7,GPR137C,PIK3R1,CCSER2,SNX10,ZFYVE21,PLCL1,JAKMIP1,PDZRN4,TRHDE,STRN3,ING3,CEP41,ZSCAN32,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RPL15,FBXW7,MCMBP,ABCA11P,AP1AR,SATB1,FNIP1,SUPT20H,CPEB3,MYO18A,CNKSR2,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,SNRPN,MYO16,PDZD2,MYCBP2,TEX2,PBLD,ITPRID2,SS18,ELOVL4,RGL1,SYNE2,SYN2,SYPL1,SYT1,CAMTA1,DOCK9,SIK3,GALNT17,TMPO,SYNPO2,TRIO,SGK3,UGT8,VLDLR,CLDND1,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,ZNF142,MFF,CADM2,EVI5,RNF103,ADAMTS9,KCNAB1,RGS7BP,PHTF2,ADAMTSL3,FXR1,NETO2" MicroRNA hsa-miR-33b*:mirSVR_lowEffct hsa-miR-33b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-76 8.55E-73 1.11E-75 1.02E-74 216 1345 "EMILIN3,SYS1,ADD2,ADORA1,KIAA1211,RNF150,PTCHD1,BEND6,SLC24A4,PCDH19,SYT13,AMPD2,PKP4,APC,FAM131A,VAT1L,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,ATP2A2,LINC00847,BID,KSR1,SYNJ2,GYG2,RAB29,CACNB4,SLC25A14,VXN,CERS5,SCARB1,CD38,SEPT7,LRRFIP1,MAGI1,ASIC3,CHN2,RAB33A,FBXO7,QKI,SRP14-AS1,RAB26,SUMF2,SLC35F1,C1QL2,GDA,SNCAIP,RGS6,GALNT9,VCAN,CTH,GIT2,SPATA2,YTHDC1,DGCR5,HEPH,ELMO1,SACS,SV2B,DPH1,EDN1,ANKRD46,CNNM1,HEYL,FAM13A,PLXNC1,EIF5,ELN,EPHB1,VPS26C,RASL12,GMPR2,HSPA12B,FAM198B,ZNF585B,DLC1,FCGRT,ZSCAN30,FGF1,SPSB4,PCYOX1,SLC37A3,FOLH1,ZNF605,AP4B1,GABRA3,GABRB3,ERAP1,DISC1,LRRC37A6P,GATM,NEU3,TUBA8,MSTN,HPGDS,TOX3,RAB40B,STON1,SERP2,GUCY1B1,PADI2,MAN1B1,MSL1,IL6R,IL6ST,KIF5A,KIT,KTN1,GPR155,LRP1B,SCAMP5,SAMD5,ADAM22,MSR1,MYO5A,HNRNPM,ZC3H12B,CCDC13,DNHD1,SLC11A2,GPR137C,PDE1B,PFKFB4,XRN1,NLE1,SLC25A23,PCDH18,SCHIP1,MAGEL2,FSD1,PPP2R5E,HYDIN,CNTLN,MTMR10,ELOVL2,PTPRE,TMEM255A,FAM184A,ZNF493,TRIM68,GTDC1,SLC25A36,ALG9,ARMC5,CCDC25,ZC3H14,ATP8B4,SGSM1,EMID1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,SEMA6D,ATXN2,ATXN7,PEAR1,CASC3,MRAS,SUPT20H,ASAP3,SHMT2,CHD9,ANKRD6,BTBD3,KANSL3,ELMO2,BTBD7,SMARCD3,RCOR3,SNCA,KIF13A,SNRPN,TMCC1,NMNAT2,NEK4,ADHFE1,SIN3B,TRIM2,PHF24,FRYL,DICER1,DICER1-AS1,ZFPM2,AP4E1,GALNT17,LRRC8A,TP53BP2,STXBP4,SGK3,RPL7L1,UBTF,UCHL1,UGT8,CCDC14,GUSBP1,XPO1,ZNF711,ZNF24,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,SLC30A4,EPM2A,RGS7BP,DOCK8,RTN4,TRAM2-AS1,RNF170,DPF3,LAS1L,SENP7" MicroRNA hsa-miR-520e:mirSVR_highEffct hsa-miR-520e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.54E-76 8.62E-73 1.12E-75 1.03E-74 215 1333 "KIAA1211,PTCHD1,MTUS1,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,STK33,STX16,DPY19L3,BACH1,BID,CFLAR,ST3GAL5,MTMR3,JAZF1,SGCE,CA12,CALB2,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,IQCK,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,GDA,SNCAIP,ARHGEF10,SOCS5,CYBB,BOC,KIAA0586,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,EDN3,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,DENND4A,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,FYB1,IGSF5,TUBGCP4,ADAM28,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPR12,GPR34,PCLO,ARHGAP36,SMAP1,MSL1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NCF2,NELL2,NF1,NRCAM,OCRL,OGG1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,EPB41L4B,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,PTPRG,CEP97,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,CCDC102B,MCMBP,RPS20,TRAPPC13,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,ZNF709,VLDLR,VSNL1,PCDH20,LYPD6,LAMP5,CADM2,PRTFDC1,LINC02210,PRDM8,PRDM10,RNF103,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-125a-3p:mirSVR_highEffct hsa-miR-125a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.64E-76 9.19E-73 1.19E-75 1.10E-74 195 1100 "CLK4,KDM5D,KLHL13,RTL9,KIAA1324,CC2D2A,USP35,ABCD2,PCDH10,BBOX1,AMT,SUGT1P4-STRA6LP-CCDC180,CADPS,LINC00173,STK33,TTLL9,ADGRB2,ADGRB3,IL33,DDR1,KALRN,CAST,SPAG9,RUNX1T1,LDB2,CERS5,P2RX6,DGKI,NUMBL,CHGB,CHN2,ANKRD35,SUMF2,ZFP28,GDA,SNCAIP,CSF1,SIPA1L1,UBXN2A,PPP6R2,ZSCAN23,DCAF4,DOCK4,ARHGAP24,DAPK1,ARMCX4,B3GAT3,LYPD1,SNAP91,DPYSL2,SLC25A18,DTNA,DTNB,ABCC5,AASDH,FRY,MBNL2,TNK2,PAN3,RABEPK,CDKL3,VPS26C,SIRPB1,ADGRV1,DLC1,ZNF589,FER,MED12L,FGF11,AGAP3,IQCG,APOPT1,STAMBP,ATP6V1H,NSG1,OGA,FYN,B4GALNT1,ERAP1,GATM,NEU3,TNRC6A,PRDM5,SOX21,PACSIN2,TNFAIP8L3,ELOVL5,HNMT,ZDHHC15,TCEAL6,MSL1,FAM95B1,SCIN,IL6ST,GPR62,KIF2A,STMN1,HECTD2,NCOA7,LSS,MAN2A2,MATN3,MBD1,LRP1B,MYO9A,NF1,NFE2L2,CNOT4,P2RX7,ZNF827,GLIPR1L2,ETFRF1,PCDH8,PDPK1,SEMA5B,CCSER2,FAM216A,LRP12,SH3KBP1,PKIA,MAPK9,HYDIN,KLK6,BCAS3,SNRK,PTCH1,ANKHD1,PTN,PTPRE,RADX,MSANTD2,ERI2,RGS4,RIC8B,RNH1,ELP2,ABCA11P,HSD11B1L,KCNIP1,SEMA6D,SATB1,TNFRSF19,FOXRED1,SGK1,SH3GL3,SHC4,ST6GAL1,NLGN1,DHX30,SLC8A1,BTBD7,MBD5,ZSWIM8,RBM26,LMO3,POGZ,LARP4,SSPO,MPRIP,RGL1,COBL,C12orf76,FAM208A,SIN3B,ZFP90,CUX2,ZEB1,SIK3,ITGB3BP,C9orf85,ELP5,PDSS1,AMACR,ZKSCAN5,TUBB2A,FAM155A,UGT8,TOM1L2,WIPF1,KLC2,TRIM9,LYPD6,ANKS1B,SMARCAD1,MAP3K12,CADM2,GDPD5,NAV3,WNK2,RGS7BP,MRPL47,UBE3B,TRAM2-AS1,FXR1,ST8SIA2" MicroRNA hsa-miR-501-3p:mirSVR_lowEffct hsa-miR-501-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-76 9.22E-73 1.19E-75 1.10E-74 202 1180 "ASPHD1,NCKAP5,XKR4,FMNL2,RNF157,KLHL13,TXNDC16,ALCAM,PCDH10,AMPD2,AMT,DPP10,SEMA4G,ZBTB10,ATP2A2,ADAM23,TTLL9,BCHE,C5,MYRF,CACNA1B,MTMR7,DCLK1,DLGAP1,PPT2,CLTC,QKI,MAP4K4,CNN3,AKAP5,TOGARAM2,SEC31B,SEC24C,LRIG1,ARHGEF10,OSBPL3,SIPA1L1,CST3,KIAA0040,ERC2,RIMS2,SEC14L5,KIAA0408,HDAC9,GAPVD1,LONRF1,KCTD8,DGKB,GIT2,SPATA2,DMD,DYNC1I1,CPEB2,DTNA,ABCC5,EDN1,HIPK3,SEMA3D,CELSR3,EGFR,LRRC17,ZNF549,ADGRV1,MRVI1,FAM198B,MED12L,FGF13,FGFR1,FLYWCH1,UFM1,TPK1,GAD1,B4GALNT1,C15orf41,GCNT2,GGTA1P,TCERG1,RAB30,GPR12,DIDO1,ADAMTS13,SERP2,ATE1,FAM19A2,RNFT2,GABARAPL2,KIF2A,LAMA2,ZFYVE27,MARK1,LYPLAL1,MBNL1,LRP1B,MID1,COL28A1,N6AMT1,MYO7A,ZNF862,TCEAL5,NEFH,NELL2,NFE2L2,ALDH1L2,SMIM11A,TBC1D25,OCRL,P2RY1,PCSK5,PFKFB3,DUSP26,ZNF655,XRN1,MTRF1L,ING3,PPM1B,DIRAS2,GDPD1,SNRK,CNTLN,MTMR10,TMEM260,PTPRO,ZNF844,TMEM255A,CCDC40,ZNF793,REV3L,RGS3,RIC8B,CYB561D1,RORB,ELP2,RPE,FBXW7,ADAL,KCNIP3,RTN1,AP1AR,SCN2B,GALNT10,SUPT20H,SYBU,NLGN1,FAM81A,PPP4R3A,ZNF430,SLC9A5,ATF7IP,TET1,SMARCC2,SNAP25,SNRPN,FAM126B,PDZD2,ATP10B,TROVE2,SSTR1,NXT2,ELOVL4,CEP68,DIP2A,KANK1,NECAB1,ZC3H4,SYNE2,VPS13A,ANKRD28,ANKRD12,MTCL1,CAMTA1,DOCK9,TEK,PMS2CL,C18orf54,AP4E1,ERCC6L2,CSMD1,NPL,DOK6,AMACR,HSPBP1,PRR18,SLC35A4,XPO1,PCDH20,ZIC1,ZNF711,ZNF708,ZNF154,TMEM198,ZFAND5,CADM2,PRDM8,ADAMTS9,TMEM178A,HRASLS,DOCK8,PHTF2,ADAMTSL3,NHSL1,IFT88,ST8SIA2" MicroRNA hsa-miR-125b:mirSVR_lowEffct hsa-miR-125b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.72E-76 9.64E-73 1.25E-75 1.15E-74 225 1456 "ACADM,ACHE,SYS1,NDRG3,ADD1,LRFN2,BEND6,MTUS1,RTL9,TXNDC16,CC2D2A,MARCH4,PI16,PKP4,KCNAB2,APC,NT5C3B,TNRC6C,AQP6,SPTBN4,SLC4A4,SLC2A11,DOCK11,CFLAR,KSR1,BMPR1B,SYNJ1,SCAPER,CACNA1B,DDR1,ISPD,ARHGEF1,SCARB1,ARHGEF2,CBARP,RAB33A,RAB28,ARHGEF6,ARMC8,ANKRD35,SUMF2,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,SIPA1L1,APPL1,PHF14,GREB1,FAM131B,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,HEPH,RUSC2,ZC3H11A,RPS6KL1,DPH1,DTNA,DTNB,ABCC5,PHC2,CNNM1,SEMA3D,PHF20L1,TMEM132E,PLEKHA1,MRPL10,ANKMY1,SCML2,FCGR1A,FKTN,STRADA,ZNF589,FER,PRKAG2,SMC2,HHIPL1,AP4B1,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,GGT7,CRCP,TCERG1,ZNF638,LOXL3,LILRA2,CCDC184,LPAR4,TMEM121B,PCLO,GRB10,GRIA2,SPACA9,RASSF8,HAS2,PADI2,MAN1B1,TNFAIP8L3,SYNPO,HMGCR,HNF4G,NKD1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KHK,KIF5A,KIFC3,SYTL4,HECTD2,NCOA7,LSS,MAP2,MAP6,ADAM11,MIA2,MSI1,MYO7A,NEFM,NUCB2,IGSF11,DPY19L2P2,ZDHHC8,ZNF655,PLCB2,RETREG2,POLG,MINDY2,MAPK10,VPS13C,CNTLN,PTH1R,PTK2,PTPRD,PTPRE,C1orf109,FAT4,ZDHHC14,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,SNX22,EPHA10,STK32B,EMID1,LRRK2,MEG3,SCN2B,SCP2,CASC3,KIF16B,MYO18A,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,LGI3,ABTB1,ANKRD36,SNRPN,DOP1A,GLT8D1,ZC3H13,SPTB,NFASC,SS18,SSPO,ELOVL4,SEPT8,ADHFE1,SYN2,SYPL1,SLC37A2,TACR1,SATB2,RPGRIP1L,DICER1,GPR161,AKTIP,BHLHB9,LRRC8A,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,BCL2L13,ELFN1,CRB2,LYPD6,TMEM198,EML6,MAP3K12,STOX2,ADAMTS9,SLC17A7,PLSCR4,PARP11,UBE3B,TMEM63C,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-1267:mirSVR_highEffct hsa-miR-1267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.31E-76 1.29E-72 1.67E-75 1.54E-74 188 1024 "SYN3,BRAP,KIAA1211,PTCHD1,HECW2,SYT13,AMPH,CCDC146,PKP4,APC,MAGEE2,SHROOM2,PPP4R4,RGS20,LINC00173,CDK13,ZBTB10,ATP1B3,MPDZ,SYNJ2,JAZF1,CA8,CALB1,CALB2,CARS,SPAG9,RUNX1T1,CBR1,C1orf52,CCPG1,SRSF11,CHN2,CLCN3,HECTD1,ARHGEF6,FAM149A,AKAP6,COL4A5,SLC4A8,SMARCAL1,SLC35F1,CLOCK,CSF2RA,CSNK1G3,SOCS5,VAC14-AS1,UBXN2A,PUM1,USP6NL,CYBB,BOC,ARHGAP32,ZFYVE16,EARS2,LONRF1,ZBTB24,HEPH,SV2B,SPOCK3,USP3,CDON,ARRDC4,EDNRA,HIPK3,FCF1,PHF20L1,EPB41L2,EPHB1,ADGRV1,SUCO,AGAP2,ANKFY1,HVCN1,APOPT1,UFM1,STAMBP,ATP2C1,CHL1,DISC1,GCNT2,PPARGC1A,MALT1,DBF4,LOXL3,DIDO1,ZBTB49,SOX21,MAP4K5,C9orf129,HSF2,KNDC1,IL6R,IL6ST,FAM69A,ITGAM,KCNN2,STXBP5,SYTL4,SMAD9,MAP4,MAT2A,MEST,PPM1L,MSR1,MYT1,NF1,PCBP3,NTRK3,OPA1,GNG2,PIK3R1,XRN1,KCTD15,PCDH18,TRHDE,ING3,GRAMD1C,MTMR10,PTPRE,PTPRG,PTPRO,ZNF615,RAD17,ZCWPW1,ERI2,RGS3,SLC25A36,RIC8B,ZNF532,ALG9,GSTCD,ABCA11P,SALL1,SEC14L1,TRA2B,SH3BGR,FERMT1,CHD9,PREX2,PPP4R3A,ARHGEF40,CCDC88A,ZNF334,RCOR3,KIF13A,USP33,BDP1,SP4,IZUMO4,ZNF423,TSPYL2,ZNF302,SSTR1,NKAIN2,STAU1,ZSCAN29,VPS13A,FAM208A,TBL1X,SZT2,ERCC6L2,PIK3R5,TPM1,TRIO,TSN,EIF4ENIF1,FLRT2,WIPF1,ZNF17,MICU3,AGMO,MKRN3,LYPD6,ANKS1B,UPF3A,INTS3,MAP3K12,MFF,STOX2,PRDM10,FIP1L1,FAM47E,FAM13C,UBE3B,SMIM8,PHTF2,ADAMTSL3,KLHDC1" MicroRNA hsa-miR-2110:mirSVR_highEffct hsa-miR-2110:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.47E-76 1.94E-72 2.50E-75 2.30E-74 196 1116 "RALGAPA1,ASIC1,AS3MT,PLEKHH1,HECW2,CASKIN1,WDR35,C1QTNF3,ZNF687,AMPD3,LRCH2,PHF12,PHYHD1,PPFIA3,LGR5,SEMA4G,RASL11B,STX16,ATP6V1G2,TTLL9,RGS11,CFLAR,BMPR1B,DST,FUBP1,MTMR2,C5,PTBP2,VXN,SPAG9,ARHGEF25,CBR1,USP2,MTMR7,CD38,C1orf52,ZMYM4,LOC730101,CNOT8,TPP1,CLTC,ARHGEF6,COL4A5,SUMF2,ZFP28,HAPLN1,RNF14,HINFP,GDA,CLIP3,SNCAIP,SUSD5,PHF14,CYBB,RIPOR2,CENPL,AIF1L,YTHDC1,SACS,SPOCK3,PDCD6IP,RCAN1,DNM1L,PHC2,FCF1,PHF20L1,C3orf18,TMEM35A,C8orf37,DCTN4,ENO2,MRPL37,SIRPB1,RPS6KC1,ACSL4,TAOK3,CORO2B,FGF14,FGFR1,FOXF2,PCYOX1,FLT1,NOP56,HVCN1,STAU2,GABBR1,GALNT15,TMEM8B,IGSF5,SRCAP,ARFIP1,PPARGC1A,ZNF276,TNRC6A,LUZP2,PCLO,GRIN2C,ADAMTS6,UBE2QL1,PADI2,ZDHHC15,LRRC75A,NKD1,IL6ST,ZNF678,FAM69A,SLC35G1,KHK,KIF5A,HECTD2,MAN2A2,MAT2A,POC1B,ADAM22,PTOV1,NF1,DNHD1,SETD4,TBC1D25,OGG1,ZDHHC8,FAM218A,SMIM7,PURG,PRIMPOL,MAPKAP1,PILRA,PRKACB,CEP41,DIRAS2,DCHS2,MASP1,BCAS3,TMEM260,CASTOR1,PTPRG,ZDHHC14,ZMAT4,ZFHX4,CCDC82,SETD5,ROBO2,YY1AP1,MRAP2,STK32B,KCNIP3,MRAS,COPZ1,SH3GL3,ASAP3,R3HDM2,NUBPL,SLA,BTBD3,SLC9A5,SLC11A1,ANKRD36,MBD5,SNRPN,MYCBP2,TEX2,SPART,ATP10B,ZC4H2,ELOVL4,ADHFE1,SYN2,MMS19,PJA1,ARHGAP9,SIK3,DICER1,ITGB3BP,SLC44A1,ARL10,RIMBP2,TRO,ANKRD20A2,TTC3,CLHC1,USP1,WIPF1,CLDND1,ZFP37,KCNT2,SPHK2,CELF4,ANKS1B,DHX33,PRDM8,PRDM10,FIP1L1,ADAMTSL3,RNF170,NETO1,PRRT4" MicroRNA hsa-miR-29b-2*:mirSVR_highEffct hsa-miR-29b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-76 2.08E-72 2.68E-75 2.47E-74 223 1437 "SYN3,CLK4,XKR4,FMNL2,PWWP2A,KIAA1211,HECW2,OSBPL6,CC2D2A,ALCAM,ABCD2,UNC79,OGT,SUGT1P4-STRA6LP-CCDC180,SPTBN4,CCAR2,STX16,N4BP2L1,DPY19L3,SEC11C,CFLAR,SYNJ2,KALRN,PTBP2,CAST,RUNX1T1,ZMYM4,L3MBTL4,MAGI1,CNOT8,RAB33A,PPT2,DGCR9,MAP4K4,CNGA3,CNTN1,RTTN,SLC35F1,FAM171B,ENTPD4,HAPLN1,HINFP,ARHGEF10,CSNK1G3,CNTNAP2,CTH,ARHGEF4,PPP6R2,CYBB,DOCK4,EARS2,TBC1D5,MATR3,PABPC5,ARMCX4,ARMCX2,DDX46,RHOBTB1,RAB39B,DNAH9,RPS6KL1,DMTF1,ARRDC4,GOLT1B,EDNRA,FRY,PHF20L1,GOLGA7,MRNIP,CALCRL,DCTN4,EIF1,EPHB1,VPS26C,TLR7,F5,CLVS1,ZNF461,FCGR1A,KAT8,GORAB,MED12L,GTF2IRD2,MEX3B,EVL,SLC37A3,TPK1,RAPGEF6,ZNF234,ZNF559,C15orf41,PCDH17,MALT1,BRD8,TCERG1,TNRC6A,MSL3,CBX1,IRAK3,RASSF8,HNF4G,C9orf129,ZDHHC15,NKD1,ZIC5,LRRCC1,KCND2,KCNN3,STXBP5,TTYH2,LMO2,HECTD2,MBD1,MBNL1,MEIS1,NF1,NTRK3,TBC1D25,IGSF11,ZNF713,PCSK1,PCSK5,PDE3A,ENPP2,GNG2,ZNF655,RETREG1,SMIM7,MTRF1L,ANKRD16,EXOSC10,SDK2,ING3,FA2H,PPM1B,PRKACB,HYDIN,WDR25,MTMR10,TMEM260,PTPN13,PTPRG,PTPRH,PTPRO,ACSS3,CCDC40,SH3TC2,NWD1,OXR1,RASGRF1,RASGRF2,KHDRBS2,TRIM68,REV3L,GTDC1,RIC8B,PBRM1,ZNF532,ROBO1,RPE,MCMBP,ZNF568,CCDC112,AP1AR,DGLUCY,SARS,SATB1,LRFN5,SHC4,HKDC1,AMBRA1,NLGN1,DZIP1,BTBD3,FAM214B,BTBD7,ZNF667,SMARCD3,LIMCH1,ZNF415,RBM26,POGZ,SAMSN1,SSTR2,ERBIN,DIP2A,KANK1,VPS13A,ADGRL3,AGTPBP1,TBCEL,IQCE,SIN3B,CUX2,SYNE1,PCDHB9,SIK3,SIRT1,GPR161,AKTIP,CDH22,THRA,NR2E1,TMPO,CSMD1,TPM1,METTL3,TTC3,UGT8,WIPF1,XRCC4,KCNT2,ZNF540,ATP6V0E2,FTSJ1,UPF3A,SLC30A4,PRTFDC1,RNF103,WNK2,HNRNPA3,FRMD6,IFT88" MicroRNA hsa-miR-409-3p:mirSVR_highEffct hsa-miR-409-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.30E-76 2.41E-72 3.09E-75 2.85E-74 206 1233 "KCNH8,CLK4,KLHL32,CCDC85A,ESYT2,KLHL13,ADGRF5,SMIM17,ALCAM,FAM135A,MAP4K3,PHF12,DDO,LGR5,ASPA,DPY19L3,BACH1,MPDZ,BLM,JAZF1,IL33,THSD7A,PTBP2,VXN,CAST,CLDN10,KRIT1,LRBA,ARHGAP33,MAGI1,CLGN,SOCS6,NDST3,LHX2,RAB28,C4orf33,HECTD1,AKAP7,AKAP6,AKAP5,ABI3BP,RCHY1,SLC35F1,CLOCK,ANKRD44,ARHGEF10,CSNK1G3,VCAN,PHACTR3,PUM1,USP6NL,KATNAL2,ZFYVE16,MATR3,KCTD8,PABPC5,SACS,SGSM2,CPEB2,DNM1L,E2F5,EDN1,FCF1,EGFR,KMT5B,EGR3,RGS17,LRRC17,GPHN,STX2,VPS26C,F5,GORAB,SEC24B,SCARA3,IP6K2,ATP13A4,HVCN1,APOPT1,UFM1,PRELID3A,STAU2,GABRG2,ERAP1,ZNF559,DISC1,GATM,IGSF5,MMADHC,USP19,GHR,MALT1,SPIN1,TNRC6A,GNAL,LNX1,FUT10,GPR12,STON1,CNTRL,BTN2A1,AGBL5,SOWAHA,KCNJ16,IPO5,LIMS1,PAXBP1,SYTL4,MBNL1,PPM1L,AFDN,ZNF680,BLOC1S2,NCAM2,NTRK2,OPA1,OXTR,CNTN3,PDE3A,SLC10A4,OLA1,FAM218A,SNX10,GPSM2,JAKMIP1,TRHDE,SCHIP1,PPP2R5E,KANSL1,CEP41,HYDIN,RELN,VPS13C,BDNF-AS,TMEM260,PTPRB,PTPRD,EML5,OXR1,RDX,RNASEL,ZFHX4,SETD5,C12orf49,RORB,YY1AP1,NEK11,ATP8B4,ABCA11P,SALL1,SCP2,SCAF8,SH3BGR,KIF16B,BTBD7,SLC22A4,RCOR3,LIMCH1,SNRPN,KDM4C,ZC3H13,LMO3,SS18,ERBIN,TTBK2,RGL1,NECAB1,SYN2,SYT1,TAL1,ZEB1,RPGRIP1L,GPRIN3,RNF175,SIRT1,AP4E1,SLC44A1,ACTR6,TMPO,TPM1,RUNDC3B,PRR18,TUBB1,RPRM,ZNF781,CLDND1,ZIC1,ZNF711,ZNF540,ZNF138,UPF3A,SLC30A4,MFF,RNF103,HPS4,FAM47E,WNK3,FAM13C,DOCK8,HNRNPA3,PHTF2,ACTR3B,NHSL1,FRMD6,DPF3,GAN" MicroRNA hsa-miR-670:mirSVR_lowEffct hsa-miR-670:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.67E-76 2.62E-72 3.36E-75 3.09E-74 247 1745 "ABHD6,NCKAP5,SYS1,TMCC3,LRFN2,DPY19L2P4,PCDH19,TBC1D14,SORCS2,CC2D2A,C1QTNF3,ALCAM,ZNF687,TRMT9B,AMPD2,SUGT1P4-STRA6LP-CCDC180,APBB2,SFMBT2,SPTBN4,LINC00173,MARK4,ZSCAN18,SLC4A4,ATP2A2,ATP6V0A1,BACH1,ADGRB2,DST,MYRF,CAST,SPAG9,NFS1,METTL6,USP6,USP2,P2RX6,ZMYM4,NUMBL,CFL2,FOXN3,B4GALT6,EPS15L1,RAB33A,PPT2,TPP1,SRP14-AS1,ANKRD35,SLC4A8,IGDCC3,ZNF385A,SEC31B,HINFP,ABCG1,ARHGEF10,CSNK1E,CSNK1G3,CNTNAP2,FAM169A,UBXN2A,GREB1,RIPOR2,RASSF2,TBC1D5,IST1,TMEM170A,DAPK1,AIF1L,ARMCX4,SPATA2,YTHDC1,ZNF804A,DDX46,GRIN3A,EDNRA,ANKRD46,CNNM1,KMT5B,AASS,COPS4,ING4,C3orf18,DENND4A,NCALD,SPEG,ANKMY1,EZH1,FAM198B,DLC1,ZNF589,SPSB4,PRKAG2,SEC23B,ANKFY1,NOP56,TMEM107,SMC2,RASL10A,ZNF605,CGREF1,DOT1L,OGA,IP6K3,GHDC,TMEM8B,DISC1,SEPT9,GFER,PPARGC1A,TNRC6A,STARD3,DCLK2,LILRA2,GRM8,SOX21,GUCY1A1,FAM222A,RASSF8,BACH2,CPT1C,DHX35,ZNF546,ITGA7,GPR62,KCNK3,KCNN1,KIF5A,KIFC3,STXBP5,SYTL4,HECTD2,MAP6,MAT2A,KCTD6,PPM1L,MSI1,LYRM9,RTL5,ZNF862,BEX5,CNOT4,NOVA1,NTRK3,NUCB2,DPY19L2P2,PDCD2,PFKFB2,ZDHHC8,DUSP26,ZNF655,SCHIP1,ING3,MBOAT7,POLR2F,POU6F1,PPM1B,RANBP3L,MASP1,RELN,PTCH1,PTH1R,PTK2,PTPRO,FAM66C,RASGRF2,ZDHHC14,RET,MRPS18A,RIC8B,RNASEL,LGI2,ROBO2,ELP2,ST6GALNAC6,ATAT1,KCNIP3,ZNF568,MAPK12,TNFRSF19,SUPT20H,TRA2B,HKDC1,AMBRA1,CHD9,ST6GAL1,WDR37,ABLIM3,PKNOX2,SLC14A1,ELMO2,ATF7IP,ABTB1,SMARCA4,MAST1,CDK5RAP2,MBD5,TMCC1,PDZD2,SOX11,SOX15,GLT8D1,ERC1,ARHGAP26,SSTR2,RGL1,DIP2A,JMJD6,SUPT5H,ADAMTS17,SYN2,ANKRD28,SLC37A2,MCF2L,ALG1,SATB2,TRIM2,DOCK9,OBSL1,TNS2,FRYL,FAM200B,PMS2CL,DICER1-AS1,TK2,LRRC8A,C9orf85,TRIO,RUNDC3B,TRPS1,SLC35A4,GORASP1,ZNF74,CRB2,LYPD6,CELF4,ZBTB38,TMEM237,MEIS3,TUBA1A,SEMA3B,FIP1L1,PLSCR4,DOCK8,RTN4,CASC15,FAM219B,SOCS4,SENP7" MicroRNA hsa-miR-501-5p:mirSVR_highEffct hsa-miR-501-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.33E-76 2.98E-72 3.82E-75 3.52E-74 221 1415 "ACADM,CLK4,PLEKHH1,PWWP2A,RNF150,BEND6,SLC24A4,AP2A2,HACE1,C1QTNF3,PKP4,APBA2,EPB41L5,CADPS,MARK4,NCOA1,BACH1,CFLAR,SYNJ2,FUBP1,CACNA1A,LURAP1,PTBP2,CAST,RUNX1T1,MTMR7,DGKI,DCLK1,ZMYM4,MAGI1,CFL2,CHN1,MS4A7,B4GALT6,CLCN3,QKI,CNTN1,IQCK,AKAP6,MYRIP,PREPL,CREM,NCOR1,CS,SLITRK5,UBXN2A,RIMS2,KIAA0586,YTHDC1,DDX46,SACS,ZNF582-AS1,PDCD6IP,DNM1L,EDN3,FCF1,PHF20L1,MBNL2,PCOLCE2,PAN3,LRRC17,CLVS1,FAM198B,FCGR1A,CEP78,GORAB,POLK,FLT1,C2orf88,ZBED3,ATP6V1H,KHDRBS3,CELF1,TVP23A,GABRA3,GALNT15,DENND2A,MTHFD2,KIAA1841,TUBGCP4,PCDH17,MALT1,GLI2,ZNF638,TDRKH,STON1,GRIA2,RNF165,PSIP1,RASSF8,HAS2,UBE2QL1,VSIG4,IGFBPL1,SMAP1,IDH3A,KCND2,KCNH2,KCNN2,KIF2A,KIT,KTN1,MAN2A2,MAP4,MARK1,MBD1,MBNL1,LRP1B,MEIS1,SRSF12,AFDN,MN1,BLOC1S2,NEXMIF,ZNF862,P2RY13,NDP,NFE2L2,NINJ2,CNOT4,NTRK2,NTRK3,TBC1D25,GLIPR1L2,PDE4B,PDE4D,NALCN,CCSER2,SNX10,XRN1,KCTD15,PLIN1,SMOX,PLXNB1,PURG,PNMA3,ANKRD16,ING3,DRAM2,CNTLN,ANKHD1,MTMR10,EML5,PTPRG,TMEM145,ZNF844,CEP97,FAM66C,RAP1GDS1,RDX,RET,RFX3,EXD2,ROBO2,PCMTD2,BAALC,ATP8B4,GLDN,LRRK2,STX1B,FAM192A,SATB1,TNFRSF19,SEC14L1,TRA2B,HSPA4L,SGK1,KIF21A,ASAP3,ST6GAL1,FAM214B,SEPHS1,ARHGEF40,ATF7IP,TET1,SMARCD3,RCOR3,ANKRD36,SNRPN,BDP1,PEG10,ZBTB43,RGL1,DIP2A,ADHFE1,STXBP1,KLHL7,ZC3H4,VPS13A,SYT1,CAMTA1,FAM208A,CUX2,RPGRIP1L,SYNE1,SIK3,PMS2CL,AP4E1,ERCC6L2,NPL,RGMB,AMACR,RPL7L1,UBE3A,UGT8,VAV1,TOM1L2,TBC1D15,XPO1,ZNF24,KCNT2,LYPD6,SLC30A4,PRDM10,RNF103,TMEM178A,FAM13C,JMJD1C,KLHDC1,FRMD6,GAN" MicroRNA hsa-miR-3147:mirSVR_lowEffct hsa-miR-3147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.25E-76 3.50E-72 4.48E-75 4.12E-74 209 1271 "VWA5B2,RALGAPA1,SYS1,XKR4,PLEKHH1,UNC5A,ADRA1D,FAHD2CP,BEND6,MTA3,AP2A2,WDR35,CC2D2A,ADGRF5,CEP126,MARCH4,LTBP4,EP400,SUGT1P4-STRA6LP-CCDC180,TNRC6C,SLC4A4,BACH1,MIR9-3HG,P2RX6,ARHGAP33,NOG,NUMBL,SRSF11,ASIC3,CPNE6,SRP14-AS1,HECTD1,AKAP7,ARMC8,ABI3BP,SEC31B,C2CD2,TRIM69,CS,SEC24C,SOCS5,PDE4DIP,SLITRK5,PLCXD3,SEC14L5,HDAC9,ARHGAP32,SNPH,EARS2,LONRF1,MAML1,ARMCX4,YTHDC1,RUSC2,DDX46,SGSM2,WDR20,GRIN3A,DNM1,DTNA,TOM1,DNM1L,AASDH,EDNRB,EGFR,RASA4,EPB41,NCALD,IGSF6,SPEG,SIRPB1,F5,CLVS1,FCGR3A,ZNF589,ATP13A4,FLT1,C2orf88,FAM49B,STAMBP,RASL10A,TPPP3,BRSK1,ZMAT1,CYP46A1,GFRA2,CSDC2,PPARGC1A,LUZP2,WDFY3-AS2,ADGRA3,TDRKH,LPAR4,ATP2B1-AS1,ADAMTS13,ADAMTS6,GUCY1A1,HAS2,PADI2,BACH2,SHISA6,FAM95B1,C2orf72,SOWAHA,LRRC25,KIAA1755,TJAP1,GPR62,ZFYVE27,MBD1,MEIS2,MSI1,MSR1,PTOV1,LYRM9,MYT1,NOVA1,OPRL1,ZNF827,PCSK5,GPR85,ZNF655,LRP12,NECAB2,ING3,EPDR1,BCAS3,PIGG,NCR3LG1,TMEM260,ZSCAN2,ZNF615,TMEM231,PID1,FAM66C,RASGRF1,PRRT2,GTDC1,UBR7,RGS12,MRPS18A,ROBO2,RPL15,SPIN3,LRRK2,ABCA11P,ST6GALNAC6,SEMA6D,ATXN2,SH3GL3,MYO18A,FBXO11,CCDC92,DZIP1,LIMS2,SLC6A8,SLC8A1,TRIM67,CDK5RAP2,SNRPN,USP33,KDM3A,ZC3H13,PBLD,SAMSN1,NKAIN2,STAU1,RGL1,SYNE2,RHBDL3,VPS13A,NUDT10,SYN1,SYN2,IQCE,NEU4,DMXL2,ZEB1,TPCN2,SYNE1,PUM2,ARHGAP9,CYB561A3,RNF216P1,DICER1-AS1,R3HDM1,METTL3,AMACR,DCBLD1,UBE3A,OSBP2,GUSBP1,ZNF74,NDRG4,ZNF177,EML6,ZNF195,UPF3A,NT5M,DNALI1,STOX2,TMEM178A,NAV3,WNK3,RTN4,KAT6A,PHTF2,ADAMTS10,NETO1" MicroRNA hsa-miR-507:mirSVR_highEffct hsa-miR-507:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.37E-76 3.56E-72 4.56E-75 4.19E-74 186 1008 "KCNH8,ABHD6,ACTN1,PWWP2A,ADRA1D,OLMALINC,HACE1,ALCAM,ABCD2,UNC79,AMPH,ZFAT,ANK2,NCOA1,ATP2B2,DOCK11,TTLL9,BACH1,RGS9,BCL7A,SYNJ1,JAZF1,PRC1,CCK,LRBA,ZMYM4,LOC730101,MAGI1,CHGB,B4GALT6,RAB28,CLTC,FAM189A2,IQCK,ARMC8,AKAP6,SLC4A8,TBPL1,MYRIP,SEC31B,ARHGEF10,PLXNA4,DZIP3,ERC2,PHF14,RIMS2,RIPOR2,LONRF1,KIAA0586,GIT2,ELMSAN1,KIAA0753,LYPD1,RHOBTB1,CPEB2,DNAJB6,EDIL3,WDPCP,EDNRA,ANKRD46,CNNM1,KLHL5,PHF20L1,KMT5B,EIF4G2,EIF5,RGS17,DCTN4,EMX2,EPHB1,SRRM1,DLC1,MED12L,FHL1,FLT1,C2orf88,POMT1,KHDRBS3,NSG1,C15orf41,GATM,TUBA8,AHDC1,PCDH17,DHRS4,PRUNE2,PCLO,GRIA2,BACH2,HMGCL,HNMT,MSL1,IDH3A,ZNF181,ZIC5,SLC35G1,KCND2,TTYH2,LAMP2,MAP4,MARK3,MATN2,MATN3,MEIS1,MIA2,COL28A1,ADAM22,NELL2,NPTX2,NTRK2,NTRK3,OXTR,GLIPR1L2,PAX6,PCDH9,ABCB1,ING3,MAPK9,SLC26A11,HYDIN,SAMD9,CNTLN,TMEM260,PTPN13,PTPRD,PTPRG,PTPRO,STRC,USP47,REV3L,RFX3,RORB,PCMTD2,CCDC102B,FBXW7,ZC3H14,STK32B,LRRK2,ABCA11P,SEMA6D,ATXN7,TNFRSF19,COPZ1,FERMT1,CHD9,PPP4R3A,DHX30,KANSL3,ATF7IP,TET1,DMRTC1,RCOR3,LMBRD1,SP4,NXT2,SEPT8,ZC3H4,ARHGEF9,ADAMTS17,ANKRD12,AGTPBP1,DMXL2,ZFP90,SYNE1,PCDHB7,FRYL,ITGB3BP,RGMB,PRR18,ZNF610,FAM155A,UBE3A,PLEKHH2,VIPR2,XRCC4,CFAP298,ZIC1,ZNF708,ZNF540,SIGLEC10,PDSS2,AMN1,UBE3B,FBXO36,RNF170,SENP7" MicroRNA hsa-miR-520c-3p:mirSVR_highEffct hsa-miR-520c-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.97E-76 3.90E-72 4.98E-75 4.59E-74 217 1368 "KIAA1211,PTCHD1,MTUS1,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,DOCK11,BACH1,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,SGCE,IL33,CA12,CALB2,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,AKAP7,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,HAPLN1,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,DCAF8,DCTN1,ZNF804A,MYEF2,ZC3H11A,GRIN3A,HS3ST2,DMTF1,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,FYB1,MEGF11,IGSF5,TUBGCP4,ADAM28,GGTA1P,GHR,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPR12,GPR34,PCLO,FICD,ARHGAP36,ZDHHC15,SMAP1,MSL1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,OCRL,OGG1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,MAPKAP1,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,CEP97,ACSS3,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,FIGN,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,PCMTD2,CCDC102B,MCMBP,RPS20,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,PLEKHH2,VLDLR,PCDH20,LYPD6,LAMP5,CADM2,LINC02210,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,CASC15,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-3158:mirSVR_lowEffct hsa-miR-3158:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.97E-76 4.46E-72 5.69E-75 5.24E-74 226 1480 "RALGAPA1,RTL9,ADGRF5,PKP4,APBA2,USP37,LGR5,SEMA4G,PRX,IGDCC4,MARK4,NCOA1,NUMB,ALDH7A1,ATP6V0A1,RIPK1,LINC00847,BMPR1B,ARHGEF7,CACNA1B,CACNB4,PTBP2,PRC1,USP2,CBFA2T2,C1orf52,FOXN3,CHN2,PLEKHB1,B4GALT6,EPS15L1,TPP1,FBXO7,CNGA3,IQCK,SUMF2,SMARCAL1,CREM,GDA,CS,SNCAIP,RGS6,SEC24C,CSNK1E,PDE4DIP,CNTNAP2,PPP1R16B,PLCXD3,GREB1,ARHGAP32,ZFYVE16,INTS1,SCRN1,RUSC2,C2CD2L,TMCC2,HS3ST2,SLC25A18,PHC2,HEYL,FAM13A,PHF20L1,MBNL2,AASS,EIF4G2,EIF1,HSD17B14,STX2,ERBB2,DENND4A,CEP85L,MRPL10,F5,CLVS1,RACK1,CHST15,FECH,POLR1B,FGF13,SUCO,IP6K2,FLT1,PSD2,AKAP3,CGREF1,ABLIM2,ZMAT1,MEGF11,GABRG2,DENND2A,B4GALNT1,RAPGEF6,ZNF559,LRRC37A6P,GCNT2,CSDC2,TTBK1,COPS8,MSL3,GPT2,ADGRA3,BTN2A1,GSN,ATOH8,HMGCL,HP,NEGR1,SHISA6,SMAP1,IRF8,SHISAL1,ZNF546,NKD1,IL6R,IL6ST,FAM69A,SLC35G1,KCNB1,KCNN2,GATD1,CREG2,MAP4,MITF,MPP2,ZNF862,P2RY13,NEFH,NF1,NFYA,NME4,NTRK2,IGSF11,DPY19L2P2,GNG2,ZNF655,SNX10,TMEM38A,PLCL1,MTRF1L,SCHIP1,SDK2,POLG,PPM1B,CEP41,HYDIN,PRPH,MASP1,NDUFS7,BCAS3,WBP1L,GDPD2,BDNF-AS,PTK2,TMEM260,ZIK1,ZSCAN2,NKAIN1,TUG1,MARCH1,SLC25A48,RBBP6,RFX2,ZDHHC4,ZNF532,CARF,ROBO1,KIRREL1,PCMTD2,SPIN3,STK32B,MEG3,SEMA6D,FERMT1,SEC31A,DZIP1,SLC12A2,SLC12A4,SMARCC2,INAVA,MBD5,CABCOCO1,ZNF415,SNRPN,USP33,DOP1A,BDP1,ZC3H13,ZC4H2,NKAIN2,KANK1,SULF2,SEPT3,ZC3H4,ARHGEF9,ADAMTS17,SYN2,TBCEL,SATB2,SZT2,SYNE1,OBSL1,PMS2CL,AP4E1,SLC44A1,TMPO,NPL,RUNDC3B,RPL7L1,UGT8,ZNF709,VIPR2,ZNF24,TRIM9,ZFP41,CELF4,ZNF177,ZNF189,FTSJ1,ZNF213,MAP3K12,CIAPIN1,NAV3,ST7,MSRB3,ADAMTS10,JPH3" MicroRNA hsa-miR-148b:mirSVR_highEffct hsa-miR-148b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.30E-76 4.64E-72 5.91E-75 5.44E-74 201 1179 "CLK4,TMEM132B,CCDC85A,AP2A2,HECW2,KCTD16,TXNDC16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,MARCH4,PCDH10,PITPNM2,AMPD3,LINC00173,NCOA1,STX16,ADAM23,ADGRB3,DST,SYNJ1,GPC2,LURAP1,CABP7,CAST,USP6,MAGI1,NOG,CFL2,SRSF11,B4GALT6,PLAA,QKI,MAP4K4,AKAP7,ARMC8,FAM149A,CNRIP1,CLOCK,SEC24C,OSBPL3,ERC2,RUBCN,BOC,HDAC9,GAPVD1,KIAA0586,TMEM170A,ZNF804A,SNAP91,SACS,WDR20,RAB39B,DMPK,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,COPS4,TNK2,TLR7,ACSL4,SCML2,FCGR1A,FER,MED12L,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,HVCN1,ATP2C1,TVP23A,NEURL4,ZNF274,C15orf41,DISC1,KIAA1841,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,RAB40B,PCLO,DIDO1,BTN2A1,RNF165,KAT7,TNFAIP8L3,ELOVL5,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,MAT2A,MATN3,MBD1,TM6SF1,PPM1L,MITF,ZNF680,MYO7A,NDP,NF1,CNOT4,DNHD1,NPTX1,NPTX2,GPR137C,PCDH9,PDE1C,PFKFB2,PIK3C2A,JAKMIP1,PLIN1,TRHDE,TATDN3,PPP3CA,KANSL1,RASGEF1B,MAPK7,MAPK10,GRAMD1C,SNRK,MTMR10,PTN,PTPRD,EML5,PPP2R3C,TMEM255A,SH3TC2,FAM184A,RBBP6,DPF2,SLC25A36,RNASEL,ZFHX4,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,ELP2,CHD9,FBXO11,FAM81A,BTBD3,WDR47,SMARCA4,LMBRD1,SNRPN,USP33,SP4,ZC3H13,CDK19,ITPRID2,NKAIN2,RGL1,VPS13A,MTCL1,ZEB1,RPGRIP1L,TCF12,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,TNS1,TPM1,VLDLR,P2RY12,XRCC4,ZNF24,SPIRE1,LINC02210,STOX2,MDH1B,EPM2A,AMN1,ST7,RTN4,FXR1,JPH3" MicroRNA hsa-miR-152:mirSVR_highEffct hsa-miR-152:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.19E-75 6.66E-72 8.48E-75 7.80E-74 202 1193 "CLK4,ABHD6,TMEM132B,CCDC85A,AP2A2,HECW2,KCTD16,TXNDC16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,PCDH10,PITPNM2,AMPD3,NCOA1,STX16,ADAM23,ADGRB3,DST,SYNJ1,LURAP1,CABP7,CAST,LDB2,USP6,MAGI1,NOG,CFL2,SRSF11,B4GALT6,PLAA,QKI,MAP4K4,AKAP7,ARMC8,FAM149A,AKAP6,COX4I1,CNRIP1,CLOCK,CS,SEC24C,LRRC3B,ERC2,RUBCN,BOC,HDAC9,GAPVD1,MATR3,KIAA0586,TMEM170A,ZNF804A,SNAP91,SACS,WDR20,RAB39B,DMPK,SLC25A18,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,STARD3NL,TLR7,FCGR1A,FER,MED12L,OLFM1,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,STAU2,NEURL4,ZNF274,C15orf41,KIAA1841,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,RAB40B,CCDC184,PCLO,DIDO1,RNF165,KAT7,MAP4K5,TNFAIP8L3,ELOVL5,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,MAT2A,MATN3,TM6SF1,PPM1L,MITF,ZNF680,MYO7A,NDP,NEK1,NF1,CNOT4,DNHD1,NPTX1,NPTX2,PDE1C,PFKFB2,PIK3C2A,JAKMIP1,PLIN1,TRHDE,EPB41L4B,PPM1B,TATDN3,PPP3CA,KANSL1,RASGEF1B,MAPK7,MAPK10,GRAMD1C,MTMR10,PTPRD,EML5,PTPRN,PPP2R3C,TMEM255A,SH3TC2,FAM184A,RBBP6,SLC25A36,RNASEL,ZFHX4,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,ELP2,SCN8A,CHD9,FBXO11,ABLIM3,FAM81A,BTBD3,WDR47,SMARCA4,SNRPN,USP33,ZC3H13,CDK19,ITPRID2,NKAIN2,RGL1,VPS13A,MTCL1,ZEB1,RPGRIP1L,TCF12,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,TNS1,UBTF,BCL2L13,P2RY12,XRCC4,ZBTB14,ZNF24,SPIRE1,CADM2,LINC02210,STOX2,MDH1B,PDSS2,EPM2A,AMN1,ST7,RTN4,FXR1,JPH3" MicroRNA hsa-miR-625:mirSVR_highEffct hsa-miR-625:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-75 7.00E-72 8.89E-75 8.19E-74 186 1012 "ABCF1,ACHE,NDRG2,AXIN2,PLEKHH1,PTCHD1,ADRB2,HECW2,KLHL13,PCDH19,WDR35,CC2D2A,SEMA6A,LTBP4,ANK2,UPRT,LGR5,SHROOM2,ARNTL,PCDHGB4,RASL11B,BACH1,BCHE,BCL7A,GPR146,FUBP1,CASTOR3,JAZF1,C5,WASF1,DDR1,KALRN,SPAG9,ZNF501,CBFA2T2,LRBA,DCLK1,CACNA2D2,CFL2,PLEKHB1,NRXN3,PPT2,TPP1,QKI,PICK1,CNTN1,LETMD1,AHCTF1,SMARCAL1,TOGARAM2,CRMP1,CRYBB1,CLIP3,SNCAIP,OSBPL3,PLXNA4,FAM169A,APPL1,CCDC144A,KATNAL2,ELMSAN1,MYEF2,WDR20,CHRDL1,EXOG,SLC12A6,DPH1,DTNA,DTNB,DUSP9,EDN1,KMT5B,ING4,TNK2,DCTN4,EMX2,RCAN2,MTSS1L,CDKL3,CLVS1,FGF1,DCTN2,ST6GALNAC3,MSANTD4,GABBR1,GABRA3,IP6K3,DISC1,TUBA8,SPIN1,GLI2,CCDC184,ATP2B1-AS1,C1QL4,PSIP1,FAM222A,ATXN2L,ARHGAP36,ACOT7,AGBL5,ZDHHC15,DHX35,LRRC75A,KIT,ADAM11,P2RY13,NDP,NTRK3,CLDN11,PCDHGC3,PKM,PLCB2,PURG,EPB41L4B,POLR2F,IRX1,PPP2R2C,MAPK9,HYDIN,MASP1,VPS13C,CNTLN,ELOVL2,TMEM260,PTPRO,RAD51D,FAM66C,SUSD4,GAL3ST4,GTDC1,UBR7,SLC25A36,SETD5,CARF,TCP11L1,ATAT1,RTN1,PPM1E,PPP4R3A,SIRT2,ELMO2,ANKFN1,ZNF423,SPTAN1,ATP10B,SEPT8,RGL1,PRRC2C,ARHGEF9,VPS13A,MTCL1,ADGRL3,ATMIN,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,RNF216P1,C18orf54,ITGB3BP,CDH22,CSMD1,ELP5,TTC3,UGT8,TBC1D15,VSNL1,ZNF32,KCNT2,AGMO,MKRN3,CELF4,REEP1,ZSCAN26,CADM2,ST7,TIGD6" MicroRNA hsa-miR-1915*:mirSVR_lowEffct hsa-miR-1915*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-75 8.65E-72 1.10E-74 1.01E-73 218 1386 "SYN3,GALNT16,FZD9,RNF150,SLC24A4,AK2,SEMA6A,ARHGAP20,ZFAT,BCAS1,PPFIA3,CDK10,SPTBN4,MARK4,SLC4A4,N4BP2L1,RIPK1,BMP7,ARHGEF7,MTMR3,CACNA1I,IL33,CACNB4,CAMK2G,SLC25A14,VXN,ARHGEF25,CBLN1,P2RX6,LRBA,SRSF11,CHN2,B4GALT6,CLTB,IGLON5,AKAP7,ZNF521,NCOR2,MROH8,ARHGEF10,CCDC144A,ARHGAP24,MATR3,IST1,SCRN1,DBI,RHOBTB1,SLC29A4,MAMLD1,E2F6,EDIL3,SEZ6L2,EDNRB,FSD1L,MBNL2,TMEM132E,IRAK4,ING4,ELN,DCTN4,SRRM1,SPEG,CDKL3,ACSL4,PTK2B,FKTN,ZSCAN30,PRMT5,FGF1,FGFR1,MEX3B,FOXF2,SYNCRIP,FLT1,ANKFY1,PSD2,NOP56,DCTN2,EFCAB2,ST6GALNAC3,DLL3,MSANTD4,DOT1L,ABLIM2,MEGF10,GATM,ALDH1L1,TUBGCP4,TUBA8,SULT1C4,MMADHC,TTBK1,TXNL4A,AIFM3,KDM2B,PCLO,TPPP,PLCD4,BTN2A1,CLASRP,FAM19A2,COQ10A,KAT7,MAP4K5,UBE2QL1,VSIG4,HSPA1L,LRRC75A,SMAP1,SOWAHA,RBPJ,DISP2,SCIN,IL6ST,A1BG-AS1,NCOA7,PACRG,SMAD9,MBD1,CHIC1,MEF2C,MMP16,MMP17,MYO7A,HNRNPM,NF1,NFYA,DNHD1,ZDHHC8,XRN1,SLC25A23,MTRF1L,PNMA3,NKAIN4,MAPK4,DCHS2,SAMD9,DEF8,PIGG,CNTLN,ELOVL2,PTN,PTPRD,CEP97,SLC25A48,IQSEC3,FIGN,RGS12,RIC8B,ARMC5,RPE,RPL15,KIAA0895L,SGSM1,TCP11L1,MAPK12,SEMA6D,ATXN7,CASC3,CHD9,FAM81A,PEX26,DHX30,KANSL3,SLC8A1,SLC9A5,CDK5RAP2,SNRPN,FAM219A,KDM4C,DDN,CLSTN2,DIP2A,STX1A,SYNE2,NUDT10,DNAJC9,SYP,TACC1,MTCL1,SATB2,CUX2,TRIM2,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,ASXL3,R3HDM1,CDK20,SYNPO2,NEIL2,UGT8,FLRT2,WRN,RICTOR,LGI4,PCDH20,ZNF24,TRIM9,ATP6V0E2,ZNF138,CELF4,MAP3K12,EMSY,VPS35L,SEMA3B,ITM2C,FZD3,FBXO36,CASC15,RNF170,SPATA13" MicroRNA hsa-miR-876-5p:mirSVR_highEffct hsa-miR-876-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.67E-75 9.35E-72 1.18E-74 1.09E-73 200 1172 "ACADM,XKR4,TMEM132B,AXIN2,PWWP2A,PCDH19,CC2D2A,TAOK1,SEMA6A,CARNS1,FAM135A,OGT,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PARG,APBA2,PHYHD1,RGS20,ATP2B2,RNF182,ALDH7A1,ATP6V1G2,RGS9,NRP2,CFLAR,CASTOR3,JAZF1,GYG2,CALB1,SLC25A14,USP6,ZMYM4,TIGD7,SRSF11,MS4A7,QKI,AHCTF1,RTTN,AKAP12,SNCAIP,CSF1,ARHGEF10,RIMS2,DCAF4,RUBCN,HDAC9,GAPVD1,DAPK1,DBN1,WDR20,DNM1L,GOLT1B,EDN1,PHF20L1,TMEM35A,EPB41,EPHB1,SRRM1,CEP85L,ZNF549,NRN1,F5,F8,CEP78,FKTN,ANKFY1,FOLH1,SMC2,TRIM16,ST6GALNAC3,AP4B1,FYB1,GALNT15,GAD1,TUBGCP4,TUBA8,SULT1C4,ARFIP1,SESN1,GLYR1,CBX1,CCDC184,GPR34,PCLO,GRB10,FICD,PSIP1,UBE2QL1,TNFAIP8L3,NEGR1,KCNN3,KIFC3,IPO5,NCOA7,SMAD1,MAP4,MAT2A,MBNL1,MEF2C,MITF,XRRA1,MSR1,LAYN,NF1,DNHD1,NTRK2,NUCB2,CLDN11,CNTN3,PAX6,PCDH18,PMP22,ING3,PPP2R5E,PRKACB,HYDIN,SNRK,CNTLN,ANKHD1,PTPRE,PTPRG,ZNF615,CEP97,SLC25A48,NWD1,RAP1GDS1,ZNF493,KCTD17,RIC8B,CARF,ROBO1,CCDC102B,TCP11L1,ABCA11P,RTN1,ZNF568,SCN8A,GALNT10,PPM1E,SHC4,HKDC1,CHD9,ANKRD6,NUBPL,ZNF430,SEPHS1,ATF7IP,ZFP1,COA1,INTS9,SNRPN,KDM4B,SPP1,KDM4C,SPART,ZNF302,NKAIN2,SS18,NXT2,SULF2,PRRC2C,SYP,ANKRD28,PJA1,ZFP90,CUX2,PCDHB4,NSD1,USP32P1,RNF175,SIK3,RNF216P1,ASXL3,RIMBP2,C9orf85,RGMB,SYNPO2,TTC3,ZKSCAN5,FAM155A,UBE2H,UBE3A,PLEKHH2,BCL2L13,ZNF781,ZNF708,MICU3,REEP1,EML6,SLC30A4,PRDM10,TRIM16L,EPM2A,AMN1,PHTF2,FBXO36,JMJD1C,KLHDC1,SOCS4" MicroRNA hsa-miR-3126-3p:mirSVR_lowEffct hsa-miR-3126-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.67E-75 9.37E-72 1.19E-74 1.09E-73 215 1350 "KCNH8,EMILIN3,KDM5D,ADCY6,CCDC85A,ADD1,UNC5A,PWWP2A,OSBPL1A,OGT,PI16,SMIM29,ADGRB1,BARD1,SEC11C,BCHE,DNAJC27-AS1,NRP2,AP1M1,DDR1,CAST,ARHGEF25,CCNH,USP6,DGKI,ZBED1,ZMYM4,NUMBL,CHN1,FBXO7,FAM189A2,AKAP6,MAGED1,MYRIP,GDA,TRIM69,ARHGEF10,OSBPL3,SUSD5,CNTNAP2,DZIP3,KIAA0040,PNPLA8,GREB1,CYBB,RIPOR2,LONRF1,SCRN1,ELMSAN1,RUSC2,KLHL3,LYPD1,DDX46,SNAP91,SPOCK3,WDR20,EXOG,GRIN3A,DMD,HS3ST2,NYAP1,NR1D2,DOCK2,SLC12A6,DRP2,SNX29,EDNRA,HIPK3,EEF1D,YAF2,PHF20L1,EGFR,EGR3,KCTD3,CALCRL,RASGRP2,ENPP6,RABEPK,ERBB2,ZNF549,ETV1,KATNAL1,EZH1,DLC1,CEP78,FCGR3A,ZNF589,AMOTL2,UBE2E3,FLNC,ANKFY1,PDLIM5,FAM120B,ZNF274,GATM,NEU3,FREM1,STARD3,PRDM5,PSIP1,ADAMTS6,MAP4K5,PADI2,FRMD5,CELF5,SMAP1,MYLK2,RBPJ,LRRCC1,DISP2,SCIN,IL6ST,KIF5A,A1BG-AS1,HECTD2,MAN2A2,MAP4,MAT2A,MEIS2,KITLG,MID1,MYO9A,NF1,NOVA1,CNTN3,DPY19L2P2,ETFRF1,ENPP2,GNG2,TRHDE,ING3,PPM1B,LRRN3,RANBP3L,EPDR1,GRAMD1C,CNTLN,MTMR10,STK32A,PTPRB,PTPRD,PTPRG,PTPRO,C1orf109,PTX3,CEP97,FAT4,RASGRF2,CCDC82,KIRREL1,RPS6KA2,LRRK2,KCNIP1,AP1AR,CASC3,GALNT10,STUM,SCAF8,FERMT1,FHOD3,NLGN1,SLC2A5,SLC6A8,KBTBD4,SLC22A4,IFT122,ANKRD36,CMTR2,SNRPN,UNC5B,ZNF423,RBM26,NFASC,NKAIN2,ZSCAN29,ELOVL4,TTBK2,KANK1,PRRC2C,PLCB1,COBL,SLC37A2,TAL1,TBCEL,SMG6,CUX2,SYNE1,CYB561A3,DICER1,SIRT1,ZFPM2,GPR161,SLC44A1,MTMR14,ERCC6L2,AMACR,PPIL6,TSN,TSC1,PRR18,PLEKHH2,WIPF1,GUSBP1,ZNF711,ZNF74,ZBTB38,REEP1,ZFAND5,DHX33,INTS3,KAT6A,FAM219B,TRAM2-AS1,MSRB3,FAM198A" MicroRNA hsa-miR-767-5p:mirSVR_lowEffct hsa-miR-767-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-75 9.74E-72 1.23E-74 1.13E-73 231 1549 "VWA5B2,ASPHD1,ACHE,KDM5D,XKR4,ADCY5,ADCY6,RNF157,ADD1,AXIN2,RNF150,ADRA1B,ZNF608,OSBPL6,ARHGAP20,PCDH10,ZFAT,OGT,LGR5,TMEFF1,ARNTL,RGS20,DOCK11,ADAM15,MPDZ,MIR9-3HG,DST,WASF1,KALRN,RUNX1T1,CERS5,SCARB1,CD38,DCLK1,ZMYM4,TIGD7,SOCS6,B4GALT6,CLTC,QKI,MAP4K4,IQCK,ARMC8,AKAP6,WHRN,MYRIP,SH2B1,ARHGEF10,VCAN,SOCS5,ERC2,UBXN2A,GREB1,RIMS2,SEC14L5,DOCK4,KATNAL2,RIPOR2,MATR3,KCTD8,GIT2,SPATA2,ELMSAN1,JAKMIP2,ELMO1,ALKBH8,DMTF1,SLC12A6,ARRDC4,DTNA,ABCC5,EDNRB,PHF20L1,EGFR,KMT5B,EGR3,KCTD3,EIF4G2,IRAK4,ELN,C8orf37,PAN3,EPHB1,ENPP6,MRPL37,MED12L,POLR1B,SYNCRIP,AGAP3,FOXO3,NBEA,SMC2,TRIM16,MSANTD4,MPP6,GALNT15,ERAP1,ZNF559,DISC1,TXNL4A,ADGRA3,GPD2,GRIA2,DIDO1,AP4S1,SOX21,PSIP1,ADAMTS6,HNMT,LRRC75A,ICA1,C2orf72,IGF1,ZIC5,IBA57,METTL21A,KIF5A,LINC00634,STMN1,LIFR,HECTD2,ZFYVE27,MARK1,MBD1,ADAM11,KCTD6,MITF,COL28A1,N6AMT1,NEXMIF,NCAM2,SFR1,NEFM,NELL2,OPRL1,NLGN3,ZNF655,PKD1,PKM,GPSM2,PLCL1,MTRF1L,STRN3,RETREG2,PPP3CA,TMEM260,ZIK1,PTPRB,NKAIN1,SLC25A48,RAD51D,OXR1,RGS12,ZFHX4,ROBO1,KIRREL1,ROBO2,YY1AP1,ADAL,STK32B,ATXN2,HES6,GALNT10,PPM1E,AMBRA1,DZIP1,WDR37,SLC6A8,ELMO2,IFT122,MBD5,ZSWIM8,HECW1,ZBTB43,RBM26,SPART,CLASP2,ZNF302,ZSCAN29,ELOVL4,CEP68,ADHFE1,KANK1,ZC3H4,ADAMTS17,SYN2,COBL,TBCEL,SATB2,ZFP90,SZT2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,ZFPM2,SLC44A1,TIAM1,TLR4,ZNF346,SYNPO2,ELP5,RUSC1,TUBB1,SLC35A4,UBTF,ZNF709,LAT2,NPDC1,PCDH20,TRIM9,DPYSL5,ZFAND5,CIAPIN1,NAV3,URM1,TRIM16L,PCBP4,MPPE1,PDSS2,DOCK8,UBE3B,FBXO36,ADAMTS10,IFT88" MicroRNA hsa-miR-424*:mirSVR_lowEffct hsa-miR-424*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-75 1.12E-71 1.41E-74 1.30E-73 182 971 "SYS1,TMEM132B,PCDH19,TAOK1,CEP126,ALK,AMPD2,AMPD3,BIN1,ZFAT,RNF182,ADGRB3,BMP7,CACNA1G,C5,CACNA1B,THSD7A,CAMK2A,SPAG9,CCNH,SCARB1,ZBED1,MAGI1,CNOT8,QKI,PCYT1B,AKAP6,SLC4A8,COX4I1,ZFP28,NRG2,AKAP12,GDA,CS,SIPA1L1,KIAA0040,PLCXD3,GREB1,BOC,KATNAL2,RIPOR2,TBC1D5,IST1,DBN1,ZBTB24,C2CD2L,LYPD1,RHOBTB1,PLPPR4,WDR20,DMPK,CDON,ARRDC4,DNAJB6,FSD1L,PHF20L1,TENM1,PCOLCE2,CALCRL,USPL1,EPB41,ERBB2,ZNF549,MRPL37,CDKL3,MRVI1,F8,FAM198B,TMEM132C,CEP78,CHST15,SPSB4,PRKAG2,FHL1,SYNCRIP,FOXO3,FLT1,NBEA,ATP6V1H,ZNF605,NEURL4,CHL1,GALC,ALDH1L1,COPS8,GNG4,GRB10,RABL2A,ZHX1,NEGR1,IPO5,STXBP5,MBNL1,MEST,MITF,AFF1,MMP16,NEXMIF,ZNF862,MYT1,NF1,NFYA,CNOT4,SLC11A2,NRCAM,IGSF11,PCSK5,PDE4D,GNG2,PFKFB2,OLA1,GPSM2,PDZRN4,LRP12,ING3,GRAMD1C,DIRAS2,PRPSAP2,PIGG,CNTLN,PTN,TMEM260,TMEM145,MARCH1,PID1,SUSD4,RASGRF2,KHDRBS2,GTDC1,RFX3,RGS12,SLC25A36,SUGCT,ROBO1,ROBO2,ARMH4,SPIN3,MCMBP,HUNK,CLIP1,SAFB,SATB1,GALNT10,FOXRED1,SUPT20H,SCAF8,SYBU,NLGN1,PKNOX2,SLC8A1,BTBD7,INAVA,SNRPN,ZHX3,CDK19,VPS13A,ANKRD12,MCF2L,ALG1,TCF4,TCF12,PUM2,ZNF106,BHLHB9,RIMBP2,KAT6B,TPM1,TTTY15,VLDLR,NPDC1,RICTOR,TCEAL7,REEP1,FSTL5,INTS3,PRTFDC1,SLC38A1,PRDM8,WNK3,DNAH10,PHTF2,SOCS4" MicroRNA hsa-miR-649:mirSVR_lowEffct hsa-miR-649:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-75 1.19E-71 1.51E-74 1.39E-73 225 1475 "ADCY8,ADD2,PLEKHH1,CC2D2A,HFM1,SEMA6A,ARHGAP20,ZFAT,LCORL,MAP4K3,APAF1,BCAS1,LGR5,CDC14B,PPP4R4,ASGR1,NUMB,RASL11B,ATP2B2,SLC2A11,N4BP2L1,RIPK1,TTLL9,BACH1,BID,CFLAR,ARHGEF7,PTBP2,CAMK2G,PRC1,CDH2,SOCS6,CHN2,NDST3,NRXN3,FBXO7,QKI,ARHGEF6,ARMC8,AKAP5,ABI3BP,AHCTF1,CLOCK,C2CD2,CRMP1,ANKRD44,CS,VCAN,PDE4DIP,CTH,DOCK4,RIPOR2,SNPH,ARHGAP24,KIAA0586,DGKB,DGKG,AIF1L,ARMCX4,MFAP3L,KIAA0319,DDX46,GRIN3A,DPYSL2,DNAJB6,EDNRA,HIPK3,CNNM1,RASGRP1,SEMA3D,MRO,EIF5,IRAK4,TENM1,PLEKHA1,EPB41L2,ETV1,ADGRV1,TAOK3,FKTN,FER,POLK,IQCG,ZMYND15,SMC2,UFM1,TPK1,KHDRBS3,STAU2,OGA,SDCBP2,CHL1,GABRB3,FAM120B,RAPGEF6,DISC1,WASHC2A,AHDC1,PCDH17,PPARGC1A,MALT1,ZNF276,TCERG1,HPGDS,MSL3,LUZP2,PRUNE2,STON1,GRIA2,SPACA9,ADAMTS13,PRDM5,ZBTB49,RABL2A,FAM222A,RASSF8,HMGCL,ZDHHC15,NEGR1,IDH3B,RBPJ,SCIN,JAK2,MAN2A2,MAP2,MATN2,LRP1B,MEIS1,MEIS2,KCTD6,PPM1L,MSI1,MXI1,NEK1,ALDH1L2,CNOT4,PCSK1,GPR85,NALCN,SNX10,ING3,RETREG2,SEPT4,PPARA,MINDY2,PPM1B,MAPK7,ELOVL2,ZSCAN32,ACSM5,NKAIN1,TMEM231,ZNF793,RAP1GDS1,ZDHHC14,TRIM68,RET,REV3L,NUDT11,ZNF532,ALG9,ROBO2,ELP2,SPIN3,MEG3,SGK1,ZFP30,PPM1E,FERMT1,FNDC3A,SEC31A,DZIP1,SLC2A5,SLC12A2,SLC22A4,ZFP1,ANKRD36,USP33,DOP1A,ZSWIM8,NMNAT2,ZC3H13,IQSEC2,NFASC,ITPRID2,LARP4,SEPT3,PLCB1,MTCL1,DNMBP,KLHL4,TCF4,DMXL2,SATB2,TPCN2,SYNE1,DOCK9,PHF24,NSD1,HIF3A,DICER1,DICER1-AS1,C18orf54,ZNF106,SLC44A1,TIAM1,HEY1,ASXL3,TP53BP1,SYNPO2,ELP5,TSC1,TTTY15,TTC3,CLHC1,CLIP2,GUSBP1,ZNF24,TRIM9,LYPD6,EMSY,NAV3,KAT6A,FAM219B,IFT88" MicroRNA hsa-miR-889:mirSVR_highEffct hsa-miR-889:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-75 1.49E-71 1.87E-74 1.72E-73 212 1317 "ACTN1,BEND6,MTUS1,TXNDC16,HFM1,TAOK1,ABCD2,PCDH10,FAM135A,OGT,DPP10,UPRT,PPP4R4,NUMB,ADAM23,BCHE,BMPR1B,DST,C5,CALB1,PTBP2,KRIT1,MTMR7,DGKI,DLGAP1,SRSF11,FAM149A,AKAP5,SLC4A8,GDA,TRIM69,OSBPL3,ERC2,APPL1,USP6NL,KIAA0408,DOCK4,ZFYVE16,KCTD8,ARMCX4,SPATA2,ZNF804A,ALKBH8,WDR20,HS3ST2,PDCD6IP,DNAJB6,ABCC5,DNM1L,EDIL3,EDN1,TMTC1,FAM13A,PHF20L1,EIF4G2,PLEKHA1,DCTN4,VPS13B,GPHN,ADGRV1,F5,RPS6KC1,FCGRT,FGF12,MEX3B,ATP13A4,TRMO,SMC2,UFM1,NSG1,FYB1,TRAF3IP2,DENND2A,GALC,ZNF234,ZNF274,SESN1,GLUL,LUZP2,KCNMB4,RAB40B,AP4S1,IRAK3,ATXN2L,ARHGAP36,MIER3,VSIG4,NEGR1,DHX35,INSM1,KCNJ16,HECTD2,PIK3AP1,MATN3,MBNL1,EFHB,SRSF12,MIA2,MITF,MSR1,MYCN,NCAM2,NF1,NFE2L2,CNOT4,PCBP3,SLC11A2,NRCAM,OPA1,P2RY1,GLIPR1L2,PCDH9,PCSK1,ZNF655,XRN1,FAM216A,PLCL1,PCDH18,MAPKAP1,EPB41L4B,MINDY2,PPP2R5E,PRKACB,DIRAS2,SAMD9,CNTLN,MTMR10,TMEM260,PTPRB,PTPRD,PTPRG,PPP2R3C,ZNF793,RAP1GDS1,KHDRBS2,ERI2,GTDC1,UBR7,PBRM1,SETD5,PCMTD2,MCMBP,ATP8B4,ZNF568,ZNF331,SEMA6D,HSPA4L,SH3GL3,CNKSR2,FAM81A,PPP4R3A,EPN2,SLC6A11,CCDC88A,SLC12A2,SLC14A1,PDZRN3,RBM34,USP33,FAM219A,PDZD2,SPP1,ITPRID2,NEK4,TTBK2,VPS13A,ASTN2,TAF9,FBXW11,TBL1X,TCEA1,SATB2,CUX2,SZT2,SYNE1,PCDHB9,PCDHB6,USP32P1,SLC35G2,SIK3,ZFPM2,ASXL3,ERCC6L2,TNS1,RUNDC3B,AMACR,TSC1,TTC3,EIF4ENIF1,USP1,VSNL1,WNT7A,RICTOR,ZIC1,ZNF540,TCEAL7,ZBTB38,SMARCAD1,EMSY,STOX2,WNK3,HRASLS,FAM13C,PHTF2,JMJD1C,TRAM2-AS1,KLHDC1,NETO2,NETO1,DPF3,RNF146,GAN" MicroRNA hsa-miR-3119:mirSVR_highEffct hsa-miR-3119:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-75 1.49E-71 1.88E-74 1.73E-73 218 1390 "ACHE,C3orf14,ADD1,AXIN2,BRAP,PWWP2A,BEND6,ADGRF5,CEP126,APAF1,APC,ARNTL,PDE8B,NUMB,RASL11B,N4BP2L1,DPY19L3,ADGRB3,FUBP1,CACNA1I,SLC25A14,ZNF501,USP2,ZMYM4,TIGD7,SRSF11,CLCN3,ABCG2,QKI,CNGA3,IQCK,AKAP6,COL4A5,SMARCAL1,TOGARAM2,MYRIP,ENTPD4,CRHBP,AKAP12,GDA,LRRC3B,ARHGEF10,SUSD5,SLITRK5,PUM1,PPP6R2,ZFYVE16,EARS2,LONRF1,KIAA0586,KCTD8,PITPNC1,YTHDC1,JAKMIP2,MYEF2,RHOBTB1,FAM107B,USP3,DNAH9,DMTF1,WDPCP,EDN3,FCF1,PHF20L1,EGFR,EIF4G2,PLEKHA1,CERCAM,VPS13B,EPB41L2,ZNF549,DNAJC27,SIRPB1,F8,NSRP1,RACK1,GORAB,MED12L,POLK,SUCO,UBE2E3,IQCG,ANKFY1,PSD2,NOP56,NELFCD,NBEA,AK8,ATP2C1,STAU2,ZMAT1,MEGF11,ZNF274,ZNF559,DISC1,PCDH17,PPARGC1A,TTBK1,CRCP,ZNF638,GNAO1,FERMT2,GPT2,LNX1,TDRKH,PRDM5,RNF165,AP4S1,SLC2A6,MAP4K5,ZHX1,ZDHHC15,MSL1,ZNF546,LRRCC1,SCIN,IL6ST,KHK,CYP27C1,KTN1,TTYH2,NCOA7,LYPLAL1,AQP11,MEIS1,POC1B,AFF1,AFDN,ZNF92,MYO9A,NPTX1,NTRK2,NUCB2,P2RY1,GPR137C,PCSK5,PDE1C,ZNF655,SNX10,PDZRN4,PPP3CA,PRKAB2,PKIA,PRPSAP2,RELN,GDPD2,SNRK,CNTLN,ZIK1,ZNF844,RAP1GDS1,DPF2,ERI2,RFX3,PBRM1,RNASEL,ZFHX4,ZNF568,LRFN5,SCN7A,FNIP1,PPM1E,ARX,PPP4R3A,BTBD3,DHX30,SLC6A8,ZNF430,SEPHS1,CCDC88A,SMARCC2,RCOR3,MBD5,SNRPN,USP33,BDP1,ATP10B,ITPRID2,ZNF302,SS18,ZSCAN29,SEPT8,RGL1,NECAB1,MTCL1,DMXL2,SYNE1,NAT16,PUM2,GPRIN3,SIRT1,C18orf54,ITGB3BP,SLC44A1,ASXL3,SYNPO2,TRIO,RUNDC3B,PRR18,CLHC1,RPRM,WIPF1,NPDC1,XPO1,ZIC1,ZNF708,ZNF28,TRIM9,ZNF138,ZNF189,FTSJ1,ZFAND5,EMSY,STOX2,FAM47E,DOCK8,RTN4,FRMD6" MicroRNA hsa-miR-2116*:mirSVR_lowEffct hsa-miR-2116*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.80E-75 1.56E-71 1.97E-74 1.81E-73 234 1591 "ABCF1,ASPHD1,ABHD6,SYS1,UNC5A,PTCHD1,SLC24A4,ALCAM,PDZD4,AMPH,EP400,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,EPB41L5,NT5C3B,PPFIA3,AQP6,SPTBN4,LINC00173,DPY19L3,SEC11C,ST3GAL5,BTK,MTMR2,CACNA1G,GPC2,CA12,CALB2,PTBP2,CAPN3,VXN,CAST,RUNX1T1,LDB2,CERS5,ARHGEF1,C1orf52,DGKI,CDH2,DLGAP1,NDST3,FAM189A2,QKI,CNR1,PCYT1B,ANKRD35,LETMD1,SLC35F1,SEC31B,C2CD2,NCOR1,SNCAIP,PDE4DIP,CTH,PUM1,CCDC144A,DCAF8,EARS2,DGKB,AIF1L,FBXL5,POM121,SPOCK3,KIF19,DLX1,EXOG,DMD,HS3ST2,NYAP1,DPYSL2,DRP2,EDNRB,CNNM1,KLHL5,FAM13A,AASS,TUBD1,LRRC17,DENND4A,TLR7,EZH1,HSPA12B,CLVS1,TUBB3,DLC1,FKTN,FECH,FGF1,SPSB4,FGFR3,PCYOX1,SEMA4D,ATP6V1H,TVP23A,MEGF11,RAPGEF6,C15orf41,INPP5K,GCK,DHRS4,RAB30,TNRC6A,MAP7D2,DCLK2,LOXL3,RASSF8,HAS2,ZHX1,ATXN2L,HLF,DHX35,SMAP1,MSL1,MYLK2,ZNF678,A1BG-AS1,IPO5,NCOA7,MAPT,MBP,MEIS1,KITLG,ZNF680,MYO9A,RTL5,NCAM2,ZC3H12B,NUCB2,CHAMP1,LOC100128398,CLDN11,ZNF713,ETFRF1,PCSK5,PFKFB3,XRN1,MTRF1L,SH3KBP1,POLR2F,CCDC144B,MAPK7,APTX,SNRK,CNTLN,BDNF-AS,ELOVL2,PTPRE,PTPRG,PTPRH,PTPRO,C1orf109,SH3TC2,C1orf54,ZCWPW1,ROGDI,RADX,UBR7,RGS4,KIF7,MRPS18A,RIC8B,PBRM1,CARF,KIRREL1,RORB,ELP2,SPIN3,GLDN,HUNK,SEMA6D,PEAR1,ZFP30,FRMPD1,SHC4,FNDC3A,NUBPL,SLA,NBPF1,SLC9A5,SLC14A1,SLC22A4,RCOR3,MBD5,SNRPN,PDZD2,BDP1,KDM4C,TSPYL2,NFASC,CLASP2,CAMTA2,ZSCAN29,KANK1,ARHGEF9,SYN2,SYP,TACR1,ANKRD12,TBCEL,TCEA1,TCF4,ZEB1,TPCN2,TNS2,TEK,PMS2CL,AP4E1,CDH22,MTMR14,TMEM9,NPL,ZNF346,ELP5,UBTF,USP1,PLPPR2,XPO1,LGI4,ZNF24,TRIM9,ZNF138,ZNF154,POLR3H,PCBP1-AS1,KCNAB1,HRASLS,FAM13C,TMEM63C,CASC15,ADAMTSL3,RNF170,DPF3,LAS1L" MicroRNA hsa-miR-135b:mirSVR_highEffct hsa-miR-135b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.92E-75 1.63E-71 2.05E-74 1.89E-73 215 1354 "GALNT13,PLEKHH1,PTCHD1,INTS2,MTUS1,ALCAM,ARHGAP20,LRCH2,PHF12,PKP4,APC,TMEFF1,ZFYVE28,ARNTL,RGS20,PDE8B,NUMB,N4BP2L1,ADAM23,BACH1,DST,ARHGEF7,CA12,CACNB4,CALM1,KALRN,PTBP2,CAMK2G,CAPN3,RUNX1T1,ZNF501,LDB2,ARHGEF2,KCNAB3,L3MBTL4,LOC730101,UBE2L6,SOCS6,QKI,ARHGEF6,CNTN1,FAM149A,ZFP28,PREPL,ENTPD4,HAPLN1,RGS6,ARHGEF10,CSNK1G3,VCAN,SLITRK5,UBXN2A,BOC,ARHGAP32,LONRF1,KIAA0586,PITPNC1,JAKMIP2,MYEF2,DDX46,FAM107B,CHRDL1,EXOG,RAB39B,PDCD6IP,EBF1,EDIL3,EDNRA,ANKRD46,HIPK3,YAF2,PHF20L1,GOLGA7,PLEKHA1,CERCAM,MRNIP,SRRM1,EYA1,MRVI1,F8,CLVS1,FAM198B,SCML2,FDFT1,FGFR1,POLK,HPCAL4,SYNCRIP,PSD2,NBEA,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,STAU2,TVP23A,OGA,ERAP1,CPLX2,GCNT2,GHR,BRD8,RAB30,FERMT2,PSIP1,AGBL5,ZDHHC15,IRF8,IL6ST,JAK2,KCND1,STMN1,PIK3AP1,MBD1,MEIS1,ZNF92,MYO6,NEFM,NPTX1,PCDH9,PDCD2,PCDH18,PURG,STRN3,SCHIP1,SDK2,DRAM2,MINDY2,PPM1B,CEP41,GDPD1,MASP1,RELN,APTX,PTK2,ZSCAN32,PPP2R3C,RAP1GDS1,ZCWPW1,ENOX1,RDX,ERI2,SLC25A36,ROBO1,CCDC25,RORB,PCMTD2,ATAT1,PPM1E,ASAP3,ABLIM3,SLA,ZNF430,SLC8A1,CCDC88A,ZFP1,ZNF667,MBD5,SNRPN,DOP1A,PDZD2,BDP1,HECW1,ZNF302,NXT2,SEPT8,RGL1,DIP2A,KANK1,STXBP1,ARC,MTCL1,KLHL4,ATMIN,CUX2,SYNE1,PMS2CL,SIRT1,C18orf54,ITGB3BP,SLC44A1,TMEM9,BHLHB9,ERCC6L2,FAM124A,KAT6B,NPL,SYNPO2,UGT8,VLDLR,TBC1D15,WIPF1,XRCC4,ZNF708,ZNF24,TRIM9,NDRG4,ZNF138,TMEM237,FTSJ1,ZFAND5,INTS3,EMSY,DNALI1,EVI5,RNF103,PLSCR4,DOCK8,ST7,RTN4,IFT88,NETO2,RNF146,SENP7" MicroRNA hsa-miR-592:mirSVR_highEffct hsa-miR-592:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.05E-75 1.71E-71 2.14E-74 1.97E-73 194 1107 "ACADM,TMEM132B,GALNT16,PWWP2A,ALCAM,DPP10,MAP4K3,MAGEE2,USP37,TMEFF1,ZFYVE28,NUMB,STX16,DPY19L3,ADAM23,TTLL9,BACH1,BARD1,NRP2,ARHGEF7,CALB1,THSD7A,KALRN,SLC25A14,SPAG9,CDH2,MAGI1,CHGB,CHN2,NDST3,NRXN3,FBXO7,CNR1,AKAP7,AKAP6,SUMF2,ZFP28,CNRIP1,CRMP1,HAPLN1,ERC2,ARHGEF4,CCDC144A,TCAF1,SNPH,LONRF1,DGKB,DAPK1,IP6K1,PABPC5,ARMCX4,KIAA0753,CPEB2,DMTF1,SLC25A18,ECM2,E2F6,SNX29,SEMA3D,FSD1L,AASS,C8orf37,MRPL37,ETV1,F8,ARMCX1,CLVS1,CORO2B,FGF12,NELFCD,PDLIM5,AP4B1,HRASLS5,GCNT2,MSTN,ADAM28,MMADHC,LUZP2,RAB40B,GNAL,GPD2,PRUNE2,PCLO,RNF165,ARHGAP36,ELOVL5,USP51,TCEAL6,IL6ST,HECTD2,MAP4,MBNL1,LRP1B,POC1B,MOV10,ZNF92,MX1,MYCN,NEK1,VWA2,NOVA1,NRCAM,GLIPR1L2,PAX6,PCDH9,PDE1C,PDE4D,GPSM2,PLIN1,ING3,POLR2F,PPP2R5E,RANBP3L,MAPK9,GRAMD1C,VPS13C,TMEM260,PTPRD,MARCH1,USP47,SUSD4,RASGRF2,ZMAT4,REV3L,PRRT2,ZFHX4,EXD2,ROBO1,ELP2,NEK11,PTGR2,CLIP1,NCBP3,SCP2,FOXRED1,ZFP30,SH3GL3,PPM1E,ST6GAL1,SEC31A,ZNF430,SLC8A1,SLC12A2,RCOR3,ANKRD36,SNAP25,SNCA,CMTR2,FAM126B,BDP1,DOK5,SP2,LMO3,SAMSN1,KANK1,RHBDL3,ARHGEF9,PLCB1,SYPL1,ANKRD28,TAL1,ADGRL3,ATMIN,RPGRIP1L,SYNE1,FRYL,TIAM1,MTMR14,ASXL3,NR2E1,ERCC6L2,PPIL6,RUSC1,UGT8,WIPF1,CLDND1,GUSBP1,ZNF708,KCNT2,ANKS1B,ZXDA,EMSY,STOX2,RNF103,HPS4,FIP1L1,WNK3,FAM13C,ST7,SMIM8,ADAMTSL3,IFT88,SPATA13,SENP7" MicroRNA hsa-miR-1278:mirSVR_lowEffct hsa-miR-1278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.36E-75 2.44E-71 3.05E-74 2.81E-73 226 1493 "CLK4,FMNL2,ADD1,PWWP2A,ADRA1D,DPY19L2P4,MTUS1,KCTD16,MARCH4,PCDH10,BBOX1,GPRASP2,PITPNM2,ZFAT,FGD2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PPFIA3,SHROOM2,CDK13,ALDH7A1,ADAM23,RGS9,KSR1,ARHGEF7,BTK,CASTOR3,RAB29,CALB1,PRC1,CDH2,NOG,FAM19A5,SULT4A1,MAP4K4,IGLON5,CNR1,PCYT1B,AKAP6,MYRIP,CREM,SH2B1,SNCAIP,CSF1,CSNK1G3,SOCS5,FAM169A,ARHGEF4,KIAA0408,DCAF8,ZFYVE16,LONRF1,MATR3,IST1,DGKB,PABPC5,HEPH,KIAA0319,DDX46,PLPPR4,KIF19,RAB39B,DMD,HS3ST2,DNAJB6,E2F6,MBNL2,EGR3,ASB3,IRAK4,COPS4,ELN,PAN3,RCAN2,GPHN,MRVI1,FKTN,SEC24B,SPSB4,SYNCRIP,RGPD5,FOXO3,SLC37A3,PDLIM5,ATP2C1,STAU2,SARAF,DOT1L,OGA,ZMAT1,B4GALNT1,ERAP1,DISC1,GCNT2,SESN1,ADAM28,CSDC2,TXNL4A,TDRKH,FUT10,MCHR1,GPR37,DIDO1,BTN2A1,AP4S1,PSIP1,ZHX1,ARHGAP36,ELOVL5,NEGR1,AGFG1,HSF2,LRRCC1,NME9,KCND2,STMN1,SMAD1,GPR155,MARK1,LRP1B,SRSF12,KCTD6,SCAMP5,MN1,MSR1,MYCN,MYO7A,NELL2,NF1,ALDH1L2,CNOT4,DNHD1,SLC11A2,SMIM11A,TBC1D25,LOC100128398,P2RX7,PCDH8,PCDH9,ZNF655,CCSER2,XRN1,MAPKAP1,LRP12,PPM1B,PPP2R5E,MAPK7,HYDIN,TMEM260,ZSCAN32,PTPRE,ZNF493,RASGRF2,GTDC1,ZDHHC4,RIC8B,ZFHX4,CCDC82,CARF,CCDC102B,BAALC,KCNIP3,CCDC112,RMI1,ATXN2,SEC14L1,GALNT10,FOXRED1,WDR47,KANSL3,PKNOX2,BTBD7,SMARCA4,SNAP25,PDZD2,BDP1,TEX2,ZNF423,ZC3H13,ZBTB43,RBM26,NFASC,SULF2,ARHGEF9,COBL,ANKRD12,CAMTA1,TBCEL,DMXL2,ZEB1,DOCK9,PCDHB3,FRYL,PMS2CL,ZFPM2,AP4E1,ZNF106,TMEM9,ERCC6L2,FAM124A,SMUG1,PDSS1,RUNDC3B,STXBP4,TRPS1,KCNE5,USP1,TBC1D15,RICTOR,GUSBP1,XPO1,PCDH20,LYPD6,STOX2,HPS4,NAV3,FAM47E,RGS7BP,FAM13C,DOCK8,ST7,KAT6A,PHTF2,TIGD6,FXR1,IFT88" MicroRNA hsa-miR-376b:mirSVR_highEffct hsa-miR-376b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.21E-75 3.47E-71 4.34E-74 4.00E-73 202 1204 "NCKAP5,TMEM132B,PWWP2A,PTCHD1,INTS2,NME5,OSBPL8,HFM1,PCDH10,LRCH2,ANK2,APC,LGR5,ZFYVE28,MARCH3,ATP2A2,ADGRB2,BARD1,PROM1,SCAPER,MTMR3,CACNA1G,CA8,LURAP1,SLC25A14,VXN,CH25H,RUNX1T1,MTMR7,SLC16A4,LRBA,SEPT7,CDO1,SRSF11,PPT2,QKI,ABI3BP,FAM171B,HAPLN1,ANKRD44,CSNK1G3,PDE4DIP,RIMS2,HDAC9,GAPVD1,LIN54,IP6K1,MYEF2,ALKBH8,WDR20,EXOG,DNAH9,DPP6,ECM2,E2F5,WDPCP,EDN1,RASGRP1,TMTC1,DCTN4,EPB41,RABEPK,SRRM1,PRMT5,SLC9B2,POLR1B,POLK,ATP2C1,KHDRBS3,ST6GALNAC3,NSG1,MEGF11,GALNT15,ZNF559,SULT1C4,ADAM28,MALT1,TOX3,CBX1,FERMT2,WDFY3-AS2,CNTRL,GRIK5,CLASRP,HAS2,MIER3,HNF4G,SMAP1,SCIN,ITPKB,METTL21A,KCNH2,STXBP5,LAMP2,LIG4,PAXBP1,PIK3AP1,MBD1,POC1B,MMP16,GIT1,LAYN,MYO9A,NCAM2,ALDH1L2,CNOT4,NUCB2,DPY19L2P2,PDE4B,SLC10A4,OLA1,FAM218A,CCSER2,SNX10,NLE1,LRP12,ING3,PPP2R5E,PRKACB,CEP41,MASP1,VPS13C,ELOVL2,SPDL1,STK32A,PTPN13,ZNF615,USP47,GAL3ST4,ERI2,RGS3,SETD5,TMLHE,CARF,ROBO1,RORB,ELP2,NEK11,EPHA10,ZNF671,KCNIP1,AP1AR,SALL1,COPZ1,FERMT1,SHC4,CHD9,FBXO11,CCDC88A,TET1,MAST1,CDK5RAP2,MYH15,RCOR3,IFT122,MBD5,MYCBP2,SPP1,KDM4C,CDK19,SPART,ITPRID2,LARP4,NKAIN2,ARHGEF9,ANKRD28,AGTPBP1,TBCEL,CUX2,PCDHB9,FAM200B,AP4E1,TIAM1,ASXL3,CABIN1,ELP5,TRIO,KCNE5,UGT8,VLDLR,VSNL1,WIPF1,KCNT2,CELF4,ZNF189,ANKS1B,SMARCAD1,DHX33,ZNF225,SLC30A3,SLC30A4,EVI5,RNF103,NAV3,PPP1R3F,PARP11,FZD3,PHTF2,ADAMTSL3,JMJD1C,IFT88,JPH3" MicroRNA hsa-miR-515-3p:mirSVR_lowEffct hsa-miR-515-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.10E-75 3.97E-71 4.96E-74 4.57E-73 212 1324 "EMILIN3,SYS1,GALNT13,ADD2,KIAA1211,PTCHD1,AK2,SYT13,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,VAT1L,CDC14B,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,CHRD,ATP2A2,RIPK1,TTLL9,LINC00847,RGS9,BID,SYNJ2,RAB29,CACNB4,HAP1,CAMK2G,SLC25A14,VXN,SPAG9,CERS5,ARHGEF1,SCARB1,CD38,SEPT7,MAGI1,ASIC3,CHN2,RAB28,STOML1,FBXO7,FAM189A2,QKI,SRP14-AS1,WHRN,SLC35F1,GDA,TRIM69,RGS6,CTH,MAML1,IST1,GIT2,YTHDC1,ZNF804A,KIAA0753,SV2B,DMD,DMTF1,DPH1,EDN1,PHC2,ANKRD46,CNNM1,SEMA3D,FAM13A,PLXNC1,CERCAM,EMX2,ERCC2,VPS26C,ANKMY1,GMPR2,HSPA12B,ZNF585B,FCGRT,ZSCAN30,FGF1,FGF11,SLC37A3,FOLH1,C2orf88,NBEA,AP4B1,GABRB3,GHDC,ERAP1,LRRC37A6P,NEU3,TUBA8,MSTN,TOX3,RAB40B,STON1,SERP2,LINGO1,GUCY1B1,SLC2A6,IDH3A,TJAP1,IL6ST,KIT,KTN1,LAMP2,STMN1,GPR155,LRP1B,SAMD5,ADAM22,MSR1,NRBP2,MYO5A,HNRNPM,ZC3H12B,DNHD1,SLC11A2,P2RX7,GPR137C,PDE1B,PFKFB4,DUSP26,XRN1,NLE1,PLIN1,SLC25A23,PCDH18,SCHIP1,FSD1,PPP2R5E,HYDIN,DIRAS2,MTMR10,ELOVL2,PTPRE,TMEM255A,FAM184A,GTDC1,SLC25A36,LGI2,ALG9,ARMC5,CCDC25,NEK11,SPIN3,ATP8B4,TCP11L1,EMID1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,TRAPPC13,SEMA6D,ATXN2,ATXN7,TNFRSF19,PEAR1,CASC3,MRAS,SUPT20H,ASAP3,SHMT2,CHD9,ELMO2,CPEB4,OGDHL,SMARCD3,MYH15,KIF13A,SNRPN,USP33,NMNAT2,SPART,NEK4,RGL1,C12orf76,TBL1X,SIN3B,TRIM2,PHF24,FRYL,DICER1,ZFPM2,GALNT17,LRRC8A,TP53BP2,STXBP4,SGK3,RPL7L1,UCHL1,UGT8,CCDC14,TBC1D15,GUSBP1,XPO1,ZNF711,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,STOX2,EPM2A,RGS7BP,DOCK8,RTN4,TRAM2-AS1,RNF170,SENP7" MicroRNA hsa-miR-490-3p:mirSVR_lowEffct hsa-miR-490-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-74 6.33E-71 7.89E-74 7.27E-73 219 1413 "RALGAPA1,ADCY6,PWWP2A,SLC24A4,MTUS1,CC2D2A,HFM1,SPARCL1,SEMA6A,ALCAM,CARNS1,LTBP4,BIN1,CCDC146,SUGT1P4-STRA6LP-CCDC180,BCAS1,TNRC6C,USP37,CPNE5,LGR5,ARNTL,ASGR1,ALDH7A1,ATP6V1G2,TTLL9,BBS2,SLC25A14,RUNX1T1,PRC1,METTL6,USP6,CD38,C1orf52,CDH2,LRRFIP1,CCPG1,FBXO7,MAP4K4,CNGA3,ARHGEF6,ABI3BP,CLOCK,SUSD5,IPCEF1,VCAN,ERC2,RUBCN,CYBB,KIAA0408,HDAC9,GAPVD1,IST1,DAPK1,MFAP3L,ALKBH8,SV2B,SEC16A,CHRDL1,DMD,USP3,DNAH9,CD99L2,DPP6,ABCC5,DNM1L,EDNRA,CNNM1,TMTC1,PHF20L1,SUGP2,EGR3,EIF1,NCALD,CDKL3,RASL12,ADGRV1,ZNF461,TAOK3,SLC9B2,FGF1,EVL,NOP56,EFCAB2,JKAMP,NBEA,ERGIC3,OGA,MEGF11,GABRA3,RAPGEF6,ZNF274,ERAP1,SIGLEC8,INPP5K,KIAA1841,GATM,TUBGCP4,GFRA2,GGT7,CRCP,TCERG1,SPIN1,GLI2,GNAO1,PRUNE2,STON1,SPACA9,PRDM5,GSTM5,RNFT2,GUCY1B1,FRMD3,SYNPO,ZNF491,ZIC5,JAK2,KCND2,STXBP5,ZFYVE27,MARK3,MAT2A,MATN2,MBD1,MBNL1,LRP1B,MID1,MOV10,SAMD5,MYO6,HNRNPM,VWA2,P2RX7,DPY19L2P2,PDE4B,CCSER2,SNX10,NLE1,SLC25A23,EPB41L4B,PPARA,PPP1R1A,MAPK9,TMEM104,MTMR10,ELOVL2,PTPRB,PTPRG,NKAIN1,SLC25A48,CCDC40,RAP1GDS1,RASGRF1,GAL3ST4,RGS12,MRPS18A,RNASEL,ARMC5,FBXW7,SPIN3,ZC3H14,GLDN,RPS20,ATAT1,TRAPPC13,HES6,TNFRSF19,SH3BGR,ZFP30,MYO18A,HKDC1,CHD9,ANKRD6,SLC8A1,ARFGAP1,SMARCD3,RCOR3,MYCBP2,KDM4C,TEX2,SPTAN1,RBM26,NFASC,CLSTN2,ZC4H2,NEK4,RGL1,CAMTA1,TBCEL,KLHL4,ATMIN,SYNE1,DOCK9,NSD1,GALNT17,ENHO,TMEM9,HEY1,ASXL3,ERCC6L2,R3HDM1,RASD2,NPL,RGMB,UBE2H,SLC35A4,BCL2L13,PCDH20,ZNF19,AGMO,LYPD6,PCBP1-AS1,ZFAND5,EMSY,SLC38A1,ADAMTS9,CIAPIN1,GAL3ST3,SLC17A7,CPNE4" MicroRNA hsa-miR-496:mirSVR_highEffct hsa-miR-496:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.36E-74 7.60E-71 9.46E-74 8.71E-73 177 928 "SYS1,RNF150,WDR35,HFM1,LCORL,PHF12,RGS20,MARCH3,ZBTB10,NCOA1,EIF4G3,ATP2A2,SYNJ1,AP1M1,WASF1,IL33,CA8,CALB1,ZNF555,NFS1,CD86,CDH2,ZMYM4,L3MBTL4,MS4A7,RAB28,QKI,ARHGEF6,CNR1,AKAP6,COL4A5,COL9A1,MYRIP,SLC35F1,CPS1,CRHBP,CRMP1,CS,CYBB,ARHGAP32,KATNAL2,RIPOR2,EARS2,LIN54,KIAA0586,MAML1,IP6K1,PABPC5,PITPNC1,ZNF804A,KIAA0319,DNM1,DTNA,EDIL3,EDN3,KLHL5,FSD1L,MRO,KMT5B,STARD3NL,CALCRL,DCTN4,ENPP6,SIRPB1,FCGR1A,GORAB,SUCO,FLT1,JKAMP,SARAF,TVP23A,ADAM28,MALT1,TCERG1,MSL3,ZNF782,WDFY3-AS2,ADGRA3,GPR34,TMEM121B,AP4S1,IRAK3,ELOVL5,HMGCR,MYLK2,IL6R,METTL21A,LYPLAL1,MATN3,MBNL1,ADAM22,P2RY13,NCAM2,NFE2L2,NOVA1,NTRK2,OXTR,PAX6,PCDH9,PCSK1,PIK3R1,GPSM2,PURG,LRP12,TATDN3,PRKACB,VPS13C,TMEM260,PTPRE,STRC,CEP97,TMEM255A,RAD51D,FAT4,RET,GTDC1,RPE,GLDN,LRRK2,SCP2,SGK1,SH3BGR,KIF21A,ARX,CPEB3,FHOD3,ANKRD6,FAM81A,BTBD3,KANSL3,SEPHS1,SLC12A2,SLC14A1,ELMO2,CPEB4,LIMCH1,MBD5,SNRPN,TMCC1,ATP10B,TROVE2,SS18,ELOVL4,SYNE2,PLCB1,COBL,TACC1,ANKRD12,FAM208A,FBXW11,RPGRIP1L,DOCK9,GPRIN3,PMS2CL,C18orf54,AP4E1,ZMAT3,SLC44A1,ERCC6L2,BEX4,PRRT1,TPM1,UBE3A,FLRT2,MTCH1,TOM1L2,TBC1D15,P2RY12,FSTL5,SMARCAD1,PRTFDC1,ADAMTS9,HPS4,FAM47E,AMN1,PHTF2,FRMD6" MicroRNA hsa-miR-626:mirSVR_lowEffct hsa-miR-626:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-74 8.43E-71 1.05E-73 9.65E-73 225 1490 "CLK4,ADD1,FZD9,ADRA1D,BEND6,AP2A2,PCDH19,ADGRF5,SEMA6A,SPOP,ALCAM,ZFAT,LRCH2,PHF12,APBB2,EPB41L5,UPRT,VAT1L,USP37,SFMBT2,ARNTL,CDK13,MARCH3,ATP2A2,ADAM15,BACH1,BARD1,BBS2,BCL7A,ARHGEF7,WASF1,CA8,CACNA1A,CACNB4,KALRN,VXN,RHBDL1,CD86,ARHGEF1,ENTPD6,C1orf52,LRRFIP1,NUMBL,RCBTB2,MS4A7,TPP1,DGCR9,SRP14-AS1,CNGA3,SUMF2,SMARCAL1,CRY2,MROH8,RGS6,CSF2RA,SEC24C,CSNK1E,OSBPL3,PDE4DIP,CST3,KIAA0040,RUBCN,BOC,DOCK4,GPRASP1,HDAC4,TBC1D5,LIN54,ELMSAN1,RUSC2,LYPD1,DDX46,ALKBH8,SGSM2,FAM107B,DLX1,EXOG,GRIN3A,DMD,DNAH9,CDON,SLC12A6,DPP6,EDN3,HIPK3,SEMA3D,PHF20L1,COPS4,RGS17,SRRM1,MRPL37,PPP1R1B,SPSB4,FGFR3,FOLH1,KHDRBS3,OGA,SDCBP2,MEGF11,INPP5K,LRRC37A6P,KIAA1841,ALDH1L1,GGT7,HPGDS,RAB30,ZNF638,GRB10,SPACA9,PRDM5,CLASRP,RNF165,FAM107A,UBE2QL1,ZHX1,MAN1B1,BACH2,HMGCL,HMGCR,SMAP1,IRF8,RBPJ,KIAA1755,SCIN,KCNN1,CREG2,HECTD2,MEIS1,AFDN,LAYN,MYO7A,MYO9A,NDP,NF1,NFYA,CNOT4,NOVA1,SMIM11A,OGG1,PCSK5,DUSP26,CCSER2,GPSM2,FAM216A,PLEC,PRIMPOL,ING3,POU6F1,MAPK3,MAPK4,MAPK9,GRAMD1C,WBP1L,WDR25,NCR3LG1,BDNF-AS,PTPRO,ZSCAN2,TUG1,ACSS3,SH3TC2,ZDHHC14,RDX,GTDC1,NUDT11,MRAP2,SNX22,BAALC,SPIN3,TCP11L1,RXRA,S100B,SEMA6D,CSRNP3,ATXN7,SCN2B,PRCD,SCP2,PEAR1,PPM1E,CHD9,ST6GAL1,SLA,PPP4R3A,SEPHS1,ARFGAP1,TMCC1,KDM4B,BDP1,KDM3A,HECW1,NFASC,SS18,ADHFE1,KLHL7,NECAB1,TACC1,SMG6,ZEB1,TPCN2,CLASP1,CRTC1,PMS2CL,ITGB3BP,THRA,C9orf85,ELP5,TRO,KCNE5,TSC1,CLHC1,HIRA,OSBP2,VLDLR,TRIM9,TCEAL7,DPYSL5,SPIRE1,LAMP5,ZFAND5,UPF3A,URM1,FBXO36,MSRB3,LAS1L" MicroRNA hsa-miR-569:mirSVR_highEffct hsa-miR-569:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-74 1.04E-70 1.29E-73 1.19E-72 182 984 "ACADM,ADD2,AP2A2,CC2D2A,TAOK1,SPARCL1,SEMA6A,ARHGAP20,ZNF687,PARG,APAF1,LGR5,STK33,CCAR2,RNF182,DPY19L3,BACH1,KSR1,DST,SYNJ1,FUBP1,JAZF1,CACNA1G,CALM1,RUNX1T1,ZNF501,KRIT1,SCARB1,C1orf52,LRBA,L3MBTL4,CCPG1,RCBTB2,SRSF11,RAB28,CLCN3,MAP4K4,CNGA3,CNTN1,AKAP5,SLC35F1,CLIP3,SOCS5,PNPLA8,BOC,GAPVD1,ZFYVE16,LONRF1,YTHDC1,FBXL5,SNAP91,SGSM2,RAB39B,DOCK2,E2F5,EDNRA,FCF1,KMT5B,GOLGA7,KCTD3,EIF5,PLEKHA1,MRNIP,PAN3,DCTN4,ENPP6,CEP85L,TUBA1B,FER,SMC2,CELF1,AP4B1,HRASLS5,CHL1,DISC1,GCNT2,MSTN,ADAM28,PCDH17,MALT1,LYVE1,PRUNE2,FUT10,GRIA2,RABL2A,GUCY1B1,ATXN2L,GABARAPL2,HSF2,SHISA6,SCIN,FAM69A,LIG4,SYTL4,HECTD2,MAP4,LYPLAL1,MEIS2,MMP16,NOVA1,SLC11A2,SETD4,DPY19L2P2,ETFRF1,SLC10A4,NALCN,PIK3C2A,XRN1,PURG,POLG,DRAM2,MINDY2,LRRN3,GRAMD1C,PTN,PTPRB,PTPRD,PPP2R3C,TMEM255A,ZNF793,OXR1,RADX,GTDC1,RFX3,UBR7,RIC8B,GSTCD,ROBO1,RPL15,CLIP1,FAM192A,SALL1,FNIP1,SH3GL3,FNDC3A,ANKRD6,KANSL3,SEPHS1,SLC12A2,BTBD7,SMARCA4,INAVA,LMBRD1,PDZD2,TSPYL2,SSTR1,LARP4,VPS13A,PLCB1,PCDHB3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AP4E1,TIAM1,TRIO,RUNDC3B,TTC3,SGK3,TBC1D15,XPO1,ZBTB14,AGMO,ZNF189,SMARCAD1,ZNF225,SLC30A4,MFF,VPS35L,PDSS2,DNAH10,FAM13C,KAT6A,PHTF2,TIGD6,NETO2" MicroRNA hsa-miR-142-3p:mirSVR_lowEffct hsa-miR-142-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-74 1.04E-70 1.29E-73 1.19E-72 195 1130 "ACTN1,RTL9,NME5,ALCAM,AMPH,ANK2,SUGT1P4-STRA6LP-CCDC180,VAT1L,USP37,PPP4R4,CASK,RGS20,ZBTB10,NUMB,N4BP2L1,RIPK1,MIR9-3HG,BID,FUBP1,SCAPER,CA8,DDR1,CALM1,CBLN1,ARHGEF2,LRRFIP1,MAGI1,CACNA2D2,SOCS6,NRXN3,CNN3,AKAP7,ABI3BP,RCHY1,TBPL1,ZFP28,FAM171B,C2CD2,CREM,HAPLN1,OSBPL3,PDE4DIP,FAM169A,DZIP3,PPP1R16B,PHF14,PLCXD3,PNPLA8,BOC,RIPOR2,IST1,DBI,ARMCX4,ELMSAN1,TMEM130,SPOCK3,DPH1,PDCD6IP,DTNA,ABCC5,DNM1L,EBF1,KLHL5,PHF20L1,EGFR,TMEM132E,KCTD3,RGS17,EMX2,LRRC17,STX2,ZNF549,NSRP1,FAM198B,RPS6KC1,GORAB,FGFR3,FLT1,ATP2C1,ZNF605,STAU2,GABRG2,LRRC37A6P,SULT1C4,MSTN,CYP46A1,GLI2,LUZP2,LNX1,PRUNE2,GRIA2,FAM19A2,GUCY1B1,RASSF8,ZHX1,IGF1,ITGAM,KCNH2,KCNQ3,KIF5A,SYTL4,NCOA7,LSS,ZFYVE27,MAP2,MARK3,MBNL1,TM6SF1,AFF1,AFDN,ADAM22,MSR1,NFE2L2,NOVA1,NTRK2,SETD4,DPY19L2P2,ETFRF1,PCSK5,XRN1,PLCB2,PCDH18,CCDC144B,PPP2R5E,CEP41,RELN,WDR25,BDNF-AS,PTPN13,PTPRB,TUG1,ZNF793,RBBP6,KHDRBS2,ERI2,RGS12,ZNF532,CARF,MCMBP,GLDN,ATAT1,S100B,ATXN2,FERMT1,FBXO11,CCDC92,CPEB4,SP4,ERC1,RBM26,LMO3,ITPRID2,ZC4H2,SS18,TMEM150C,ANKRD28,FBXW11,TBL1X,SATB2,ZEB1,TRIM2,DOCK9,HIF3A,SIRT1,C18orf54,AKTIP,TIAM1,RIMBP2,SYNPO2,SMUG1,TUBB1,UBE2H,VLDLR,CLDND1,PCDH20,ZNF540,ZNF138,ZBTB38,ANKS1B,ZNF195,NT5M,EVI5,PRDM8,FAM47E,PLSCR4,FAM13C,AMN1,FZD3,ACTR3B,JMJD1C,TIGD6,NHSL1,FXR1,NETO2,FAM198A" MicroRNA hsa-miR-663b:mirSVR_lowEffct hsa-miR-663b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-74 1.32E-70 1.64E-73 1.51E-72 202 1213 "ACADM,ASIC1,NDRG2,GALNT16,PSMG3-AS1,ADD1,ADORA1,UNC5A,PWWP2A,KCTD16,SORCS2,ADGRF5,ZNF687,AMT,PKP4,APBA2,FAM131A,PPFIA3,USP37,SHROOM2,CDC14B,CDK10,SEMA4G,SPTBN4,ARHGDIA,LINC00173,RASL11B,ATP2B2,ADAM15,NRP2,ARHGEF7,CACNA1I,BAIAP3,CACNA1A,CABP7,KALRN,HAP1,SPAG9,CBR1,CBS,SYNGR3,MAGI1,CRLF1,CFL2,ASIC3,CHRNA4,PPT2,PCYT1B,SH2B1,RASGEF1C,CTH,RUBCN,SEC14L5,BOC,KATNAL2,ZNF337,INTS1,TIAM2,RUSC2,RHOBTB1,FAM107B,DMPK,HS3ST2,HIPK3,CNNM1,HEYL,SUGP2,EBI3,IRAK4,STX2,SPEG,ETV1,PTK2B,FCGRT,OLFM1,FGF11,IP6K2,FOXO3,EVL,PSD2,FLYWCH1,C2orf88,WDR83,ABLIM2,SDCBP2,NEURL4,INPP5K,GATM,TUBA8,DHRS4,GLYR1,MSL3,KCNMB4,FERMT2,GRB10,GRM2,VSIG4,SYNPO,HMGCL,HNF4G,C9orf129,LRRC75A,SHISA6,ICA1,IL6R,KCNB1,KCND1,TTYH2,MAP4,MAP6,MYO7A,MYT1,VWA2,NPTX1,OPRL1,ZNF713,PDE4B,PFKFB2,ZNF655,ZFYVE21,PLIN1,SMIM7,PLXNB1,PNMA3,MAPKAP1,SEPT4,DRAM2,PPP2R2C,PRKAB2,SLC26A11,GRAMD1C,HYDIN,CYBC1,SNRK,TMEM104,TMEM260,PTPRG,ZNF615,USP47,FAM66C,RASGRF1,MSANTD2,DPF2,GTDC1,UBR7,RGS3,PRIMA1,RIC8B,CARF,RORB,EPHA10,SCN2B,FERMT1,FNDC3A,BTBD3,ARHGEF40,CCDC88A,SLC9A5,ELMO2,ARFGAP1,KIF13A,FAM126B,TRERF1,SPTAN1,IQSEC2,TSPYL2,STX1A,KLHL7,ZC3H4,RHBDL3,TMEM150C,ALG1,AGTPBP1,NEU4,CUX2,SYNE1,PHF24,PUM2,RNF216P1,ENHO,TK2,CABIN1,C9orf85,ZNF346,SYNPO2,HIRA,BCL2L13,CCDC14,RICTOR,GUSBP1,ZNF74,CELF4,AMZ1,TMEM198,SPIRE1,DHX33,SEMA3B,PLSCR4,ST7,CASC15,TTC7A,FAM181A" MicroRNA hsa-miR-520d-3p:TargetScan hsa-miR-520d-3p TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-302e:TargetScan hsa-miR-302e TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-302c-3p.1:TargetScan hsa-miR-302c-3p.1 TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-520c-3p:TargetScan hsa-miR-520c-3p TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-520b:TargetScan hsa-miR-520b TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-373-3p:TargetScan hsa-miR-373-3p TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-520a-3p:TargetScan hsa-miR-520a-3p TargetScan 3.37E-74 1.89E-70 2.32E-73 2.13E-72 157 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-2114*:mirSVR_lowEffct hsa-miR-2114*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.91E-74 2.19E-70 2.69E-73 2.47E-72 210 1312 "KCNH8,KDM5D,NDRG3,PSMG3-AS1,CCDC85A,FZD9,KIAA1211,AP2A2,TXNDC16,CC2D2A,ABCD2,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APOC2,IGDCC4,LINC00173,ATP2B2,KIF1A,TTLL9,BBS2,SYNJ2,MTMR3,IL33,CA4,KALRN,HAP1,PTBP2,RUNX1T1,SCARB1,ENTPD2,LHX2,EPS15L1,PPT2,NGEF,LY86,IGLON5,SLC4A8,ABI3BP,SH2B1,ANKRD44,SEC24C,LRIG1,SUSD5,FAM169A,MYADM,EARS2,ZNF337,DAPK1,GIT2,KIAA0753,RHOBTB1,CHRDL1,DNM1,USP3,CD99L2,MED12,DMTF1,DPYSL2,GOLT1B,PHC2,FCF1,TMTC1,YAF2,KMT5B,EMX2,EPHB1,RRAGB,SIRPB1,GMPR2,CHST15,GTF2IRD2,OLFM1,HPCAL4,NELFCD,USP21,CGREF1,SARAF,TPPP3,FYB1,SDCBP2,FAM120B,SIGLEC8,GCK,GGTA1P,ZNF276,TCERG1,RNPS1,TOX3,ZNF638,KCNMB4,DCLK2,CCDC184,STON1,STMN2,GRIN2C,GRM2,CLASRP,GSTM5,SOX21,FAM107A,SLC2A6,ATOH8,FRMD5,VSIG4,SYNPO,SHISA6,SCIN,INPP5B,KCNK3,KHK,KIFC3,HECTD2,NCOA7,ZNF667-AS1,ADAM22,MSR1,CCDC13,DNHD1,SMIM11A,TBC1D25,PALM,PCDH9,PDE4D,GNG2,XRN1,KCTD15,MBOAT7,POLG,PPARA,MAPK7,CNTLN,BDNF-AS,TMEM260,C1orf109,NWD1,RASGRF1,CRTAC1,ZMAT4,ERI2,RGS4,RGS12,ROBO1,MRAP2,SNX22,NEK11,ATP8B4,GLDN,STK32B,MAP6D1,HSD11B1L,ZNF331,DGLUCY,SEMA6D,SMPD3,WDR37,NAPB,BTBD7,SLC22A4,ARFGAP1,SMARCC2,CDK5RAP2,INTS9,SP2,ZSWIM8,UHRF1BP1L,PEG10,IQSEC2,NFASC,MESP1,NKAIN2,STAU1,TTBK2,PHLDB1,RHBDL3,DNAJC9,PLCB1,SYN2,MLST8,PDLIM2,TCF4,ZEB1,TPCN2,TRIM2,FRYL,HIF3A,PMS2CL,ZFPM2,AP4E1,CDH22,SLC44A1,CSMD1,PIK3R5,TPM2,RUSC1,SLC35A4,SPHK2,TMEM198,ZNF213,DHX33,INTS3,GAL3ST3,URM1,PDSS2,FAM13C,DOCK8,ST7,UBE3B,FXR1,AP3B2,SOCS4" MicroRNA hsa-miR-573:mirSVR_highEffct hsa-miR-573:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.98E-74 2.23E-70 2.73E-73 2.51E-72 207 1276 "CLK4,CCDC85A,ADD1,ADD2,PWWP2A,BEND6,SPARCL1,FAM135A,AMPH,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,DDO,CDK13,MARCH3,NCOA1,STX16,BACH1,ADGRB2,DST,SYNJ2,MTMR2,JAZF1,IL33,CACNA1B,KALRN,NFS1,LDB2,METTL6,P2RX6,CD86,SCARB1,CDH2,ZMYM4,LRRFIP1,L3MBTL4,CACNA2D2,CHGB,CHN1,CHN2,RAB33A,NRXN3,CLTC,AKAP6,LETMD1,SLC4A8,BAG4,GDA,VCAN,PDE4DIP,PHF14,CYBB,LIN54,MYEF2,KIAA0319,DDX46,RHOBTB1,SV2B,USP3,DMTF1,DNAJB6,EDNRB,FAM13A,PHF20L1,EGFR,RASA4,AASS,GOLGA7,RRAGB,SIRPB1,CLVS1,SH3YL1,ZNF589,FGF11,FGF14,FLT1,NELFCD,AKAP3,TMEM107,SMC2,HVCN1,ST6GALNAC3,NSG1,STAU2,ZNF44,CHL1,GABRG2,TRAF3IP2,FAM120B,GALC,B4GALNT1,SULT1C4,PCDH17,GHR,COPS8,LOXL3,GPD2,SERP2,GUCY1A1,IRAK3,DDX19B,ELOVL5,C9orf129,HSPA1L,SMAP1,KCNN2,LAMP2,LMO2,MAP4,MATN2,MBNL1,EFHB,MEIS2,XRRA1,MOV10,MSR1,MXI1,ZNF862,NEK1,NF1,NOVA1,NTRK2,NUCB2,PCDH9,PCSK5,SNX10,PRIMPOL,TRHDE,EPB41L4B,GRAMD1C,VPS13C,DEF8,TMEM260,PTPRD,PTPRE,PTPRO,ZSCAN2,PID1,CEP97,SLC25A48,OXR1,RASGRF2,RBBP6,RADX,DPF2,ERI2,GTDC1,EXD2,EPHA10,ATP8B4,ABCA11P,ZNF331,AP1AR,SEMA6D,ATXN2,SCP2,COPZ1,SH3GL3,CHD9,CNKSR2,SYBU,NLGN1,PREX2,BTBD3,ZNF430,SEPHS1,BTBD7,CPEB4,SNAP25,SNRPN,SP4,PBLD,ERBIN,DIP2A,ADHFE1,SYT1,MCF2L,SATB2,TRIM2,SYNE1,PCDHB4,GPRIN3,FAM200B,ITGB3BP,ERCC6L2,KAT6B,RUNDC3B,ZKSCAN5,XPO1,XRCC4,ZBTB14,KCNT2,ZNF74,MKRN3,ZNF184,ANKS1B,TFIP11,MFF,TMEM178A,WNK3,FAM13C,FBXO36,JMJD1C,RNF146,SENP7" MicroRNA hsa-miR-302d-3p:TargetScan hsa-miR-302d-3p TargetScan 4.15E-74 2.32E-70 2.83E-73 2.61E-72 157 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-302a-3p:TargetScan hsa-miR-302a-3p TargetScan 4.15E-74 2.32E-70 2.83E-73 2.61E-72 157 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-520e:TargetScan hsa-miR-520e TargetScan 4.15E-74 2.32E-70 2.83E-73 2.61E-72 157 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-372-3p:TargetScan hsa-miR-372-3p TargetScan 4.15E-74 2.32E-70 2.83E-73 2.61E-72 157 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-302b-3p:TargetScan hsa-miR-302b-3p TargetScan 4.15E-74 2.32E-70 2.83E-73 2.61E-72 157 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,ATP2B2,AZGP1,BCL7A,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,DLGAP2,CFL2,B4GALT6,ARMC8,LETMD1,AKAP5,RCHY1,CLOCK,C2CD2,ARHGEF10,IPCEF1,FAM169A,ARHGAP24,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,CPEB2,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,PLXNC1,EIF5,RGS17,C3orf18,PAN3,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PCDH17,GNAL,GPR12,ATE1,PTPRT,KAT7,BVES,MIER3,HLF,MSL1,ITPKB,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NFYA,NNAT,PCBP3,NRCAM,GPR137C,PKD1,PLCL1,POU6F1,KANSL1,PRKACB,PTPRD,PTPRG,FAT4,OXR1,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RPS6KA2,RTN1,SATB1,SBF1,HSPA4L,FAM102A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,IQSEC2,CDK19,LMO3,RGL1,CUX2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,AKTIP,ASXL3,NR2E1,RGMB,NR2C2,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,FAM219B" MicroRNA hsa-miR-2861:mirSVR_lowEffct hsa-miR-2861:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.25E-74 2.38E-70 2.89E-73 2.66E-72 234 1613 "DGCR6,ABCF1,ASPHD1,EMILIN3,NCKAP5,KDM5D,FMNL2,RNF157,BRAP,UNC5A,PTCHD1,PCDH19,SPOP,TRMT9B,ZFAT,LRCH2,PPFIA4,APAF1,KCNAB2,APOC1,VAT1L,PPFIA3,SEMA4G,MARK4,CCDC74A,NCOA1,CCAR2,ATP1A3,N4BP2L1,TTLL9,ADAM15,ADGRB1,MYRF,BAIAP3,KALRN,P2RX6,DCLK1,EVI5L,CACNA2D2,FOXN3,ASIC3,TAOK2,NRXN3,PPT2,QKI,AKAP7,FAM149A,COL11A2,ZNF521,CLIP3,CSF1R,SEC24C,CSNK1E,VAC14-AS1,DZIP3,GREB1,FAM131B,CCDC144A,TCAF1,SNPH,DCAF8,SCRN1,DBN1,ELMSAN1,B3GAT3,KIAA0753,KIAA0319,POM121,RHOBTB1,TMCC2,DNM1,NYAP1,RPS6KL1,SLC29A4,DOCK2,DUSP9,EGFR,RASA4,TENM1,MTSS1L,SLC43A2,NCALD,MRPL37,ANKMY1,MRVI1,EZH1,REEP2,FAM198B,CEP78,STRADA,ZNF589,HPCAL4,SYNCRIP,SLC37A3,ST6GALNAC3,BRSK1,NEURL4,ZNF274,GCNT2,TUBA8,CSDC2,GGT5,ZNF276,TNRC6A,LOXL3,ZNF782,WDFY3-AS2,GP1BB,LILRB4,CNTRL,ADAMTS13,GRM2,LINC01089,RNF165,AP4S1,SLC2A6,PADI2,DDX19B,AGBL5,ZDHHC15,CPT1C,MYLK2,INPP5B,LIMS1,PIK3AP1,ZNF667-AS1,MAP6,MAPT,MATK,MEIS1,KITLG,SCAMP5,PTOV1,NNAT,NPTX2,OCRL,GLIPR1L2,PALM,PFKFB2,PFKFB4,ZDHHC8,DUSP26,NLGN3,TMIE,CCSER2,KCTD15,SLC25A23,PLXNB1,SEPT4,FA2H,MAPK4,MASP1,VPS13C,GDPD2,CNTLN,TMEM260,PTPRE,PEX2,NKAIN1,SLC25A48,USP47,IQSEC3,RASGRF1,DPF2,ERI2,RGS12,KIF7,CCDC82,CYB561D1,CCDC102B,SNX22,KIAA0895L,ATP8B4,STK32B,EMID1,MEG3,MAPK12,SBF1,PRCD,SCP2,HES6,PPM1E,BTBD3,SEPHS1,ARHGEF40,SLC12A4,ELMO2,SMARCC2,SNRPN,FAM219A,TEX2,LHPP,ZC4H2,NKAIN2,SSPO,ZSCAN29,DIP2A,ARC,ANKRD28,MTCL1,MLST8,DNMBP,SMG6,KLHL4,SIN3B,TPCN2,RPGRIP1L,SYNE1,NAT16,PHF24,FAM189A1,OBSL1,USP32P1,ARHGAP9,HIF3A,RELL2,FAM124A,ANKRD24,PRRT1,TPM2,ZNF346,TRO,UBE2H,OSBP2,RBFOX3,ZIC1,POLR3H,SEMA3B,URM1,WNK2,FZD3,UBE3B,FAM219B,PRRT4" MicroRNA hsa-miR-3180-5p:mirSVR_highEffct hsa-miR-3180-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.92E-74 2.76E-70 3.35E-73 3.08E-72 223 1474 "ASPHD1,TMEM132B,SLC24A4,ZNF608,HECW2,KLHL13,HACE1,SPOP,ABCD2,ARHGAP20,OGT,SEMA7A,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,PRX,ARRB2,CDK13,NCOA1,BACH1,SEC11C,SYNJ2,SCAPER,THSD7A,KALRN,CAST,RHBDL1,PRC1,MTMR7,SLC16A4,CD86,SEPT7,LRRFIP1,CDR1,CCPG1,SRSF11,CHN2,RAB28,FBXO7,ABCG2,ABI3BP,CREM,RBM39,ANKRD44,GDA,CS,RGS6,PLXNA4,PHF14,CTH,KIAA0408,DOCK4,TCAF1,DCAF8,ZFYVE16,ZBTB24,KIAA0753,SACS,DMD,NR1D2,DPP6,PDCD6IP,DTNA,ABCC5,ANKRD46,RASGRP1,FAM13A,PHF20L1,SUGP2,CALCRL,EPHB1,RABEPK,STX2,ETV1,TLR7,F5,CORO2B,RACK1,CEP78,FDFT1,FGF11,FGF12,PRKAG2,POLK,NBEA,TMEM107,SMC2,FAM49B,ATP6V1H,CELF1,OGA,ZMAT1,HRASLS5,IP6K3,IQGAP2,DISC1,INPP5K,GCNT2,SESN1,COPS8,DBF4,SPIN1,TNRC6A,GPT2,TDRKH,GRIA2,AP4S1,GUCY1B1,PADI2,GABARAPL2,NEGR1,IDH3B,ITPKB,SLC35G1,KCNJ16,KIF2A,SYTL4,SMAD1,MAN2A2,MAP4,MEIS2,SRSF12,COL28A1,ADAM22,NDP,SFR1,NF1,NOVA1,NPTX1,NTRK2,OXTR,P2RY1,PDE4B,PDE4D,GNG2,CYTL1,PIK3C2A,FAM216A,SEPT4,DRAM2,PPARA,PPP2R5E,PKIA,DIRAS2,GDPD1,DCHS2,VPS13C,SNRK,BDNF-AS,PTPRN2,MARCH1,SUSD4,ZCWPW1,ENOX1,REV3L,PRRT2,RIC8B,ZFHX4,TMLHE,CCDC25,RPE,BAALC,ZC3H14,TCP11L1,MEG3,ABCA11P,KCNIP1,RXRA,ZNF331,MRAS,ZFP30,FERMT1,NUBPL,WDR37,ABLIM3,CCDC88A,SLC9A5,SLC12A2,BTBD7,SMARCD3,ANKRD36,CMTR2,KDM3A,SP4,SPP1,SS18,ERBIN,VPS13A,ANKRD28,KLHL4,CUX2,RPGRIP1L,RNF216P1,FAM200B,PMS2CL,ITGB3BP,AP4E1,MTMR14,TMPO,FAM124A,WBP2,HSPBP1,SLC35A4,UBTF,VSNL1,ZBTB14,ZNF24,MICU3,ZSCAN26,ZXDA,EMSY,MFF,PRDM8,PRDM10,NELFE,CASC15,RSPRY1,TRAM2-AS1,TTC7A,ZDHHC20,FXR1,SPATA13" MicroRNA hsa-miR-25:mirSVR_highEffct hsa-miR-25:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.94E-74 3.32E-70 4.03E-73 3.71E-72 184 1013 "SYN3,NCKAP5,TMCC3,KIAA1211,TXNDC16,C1QTNF3,MARCH4,FAM135A,PITPNM2,DPP10,ATP2A2,DOCK11,ADAM23,ADGRB3,MPDZ,HCN2,SYNJ1,CACNA1I,CA8,KALRN,CAMK2A,LDB2,MTMR7,SOCS6,NDST3,NRXN3,HECTD1,AKAP6,CNRIP1,FAM171B,CRHBP,SOCS5,FAM169A,SLITRK5,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,PLPPR4,SACS,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,FHL1,POLK,ATP13A4,SLC37A3,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,B4GALNT1,IQGAP2,GGTA1P,GHR,SPIN1,GLYR1,GPD2,GPR12,LPAR4,TPPP,DIDO1,HAS2,UBE2QL1,MIER3,ELOVL5,HNMT,MSL1,SLC6A17,C2CD4C,LAMP2,LIG4,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,P2RX7,GPR137C,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,TRHDE,STRN3,ING3,CEP41,BDNF-AS,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,FNIP1,TRA2B,CPEB3,MYO18A,CHD9,FBXO11,CNKSR2,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PDZD2,MYCBP2,TEX2,PBLD,ITPRID2,ELOVL4,RGL1,SYNE2,SYN2,SYPL1,SYT1,COBL,CAMTA1,SATB2,SYNE1,DOCK9,SIK3,FAM200B,TMPO,CSMD1,SYNPO2,TRIO,SGK3,VLDLR,CLDND1,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,MFF,EVI5,RNF103,NAV3,RGS7BP,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-96*:mirSVR_highEffct hsa-miR-96*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.19E-74 3.46E-70 4.20E-73 3.87E-72 200 1196 "PTCHD1,BEND6,WDR35,AMPH,LCORL,ARSE,LINC00173,ASPA,ADAM23,BACH1,ADGRB3,SEC11C,KSR1,MTMR2,CA8,DDR1,PTBP2,VXN,CAST,CARS,LDB2,KRIT1,CERS5,DGKI,LARGE1,CDO1,SRSF11,CHGB,B4GALT6,NDST3,QKI,CNTN1,ARMC8,LETMD1,ABI3BP,TBPL1,ZNF521,CNRIP1,C2CD2,AKAP12,GDA,PDE4DIP,CST3,KIAA0040,CCDC144A,GPRASP1,LONRF1,KCTD8,DGKB,BRINP1,ZC3H11A,SPOCK3,DLX1,NR1D2,CPEB2,DTNA,EDNRA,KLHL5,TMTC1,KMT5B,C8orf37,RCAN2,ENPP6,CEP85L,MRPL10,EZH1,ABCA8,FER,FLT1,TMEM107,SMC2,PDLIM5,ERGIC3,STAU2,GABRB3,GABRG2,IQGAP2,DISC1,KIAA1841,SULT1C4,MSTN,ARFIP1,COPS8,GLI2,GLYR1,MSL3,KDM2B,RAB40B,GPR12,DIDO1,CLASRP,FAM19A2,RABL2A,MAP4K5,MIER3,ELOVL5,NEGR1,HSF2,SMAP1,IL12A,KCNN2,LMO2,MARK1,MARK3,KITLG,AFDN,NRBP2,P2RY13,PCDH9,PDCD2,GNG2,FAM218A,PLCL1,TRHDE,EXOSC10,EPB41L4B,PPM1B,PRKACB,GRAMD1C,MASP1,SAMD9,BDNF-AS,SPDL1,PTN,PTPRD,PTPRO,RBBP6,RBBP8,SLC25A36,PBRM1,CCDC82,SETD5,KLHDC8A,CARF,ROBO1,RORB,FBXW7,STK32B,LRRK2,PTGR2,ABCA11P,SATB1,SUPT20H,TRA2B,CPEB3,SHC4,NLGN1,PPP4R3A,EPN2,COA1,LIMCH1,CMTR2,ANKFN1,ZNF415,SNRPN,KDM3A,KDM4C,CDK19,MCF2L2,RBM26,ITPRID2,THSD1,SSTR1,LARP4,NXT2,TTBK2,DNAJC9,PLCB1,SYPL1,TACR1,ANKRD12,TAF9,ZEB1,SYNE1,GPRIN3,FRYL,SIRT1,KHDC1,HEY1,RIMBP2,RUNDC3B,SSBP2,CLHC1,TUBB1,FLRT2,USP1,CCDC14,XRCC4,ZIC1,MICU3,MKRN3,DNALI1,ADAMTS9,WNK3,PLSCR4,EPM2A,DNAH10,PHTF2,NETO1,SENP7" MicroRNA hsa-miR-3117:mirSVR_lowEffct hsa-miR-3117:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.87E-74 3.85E-70 4.66E-73 4.29E-72 185 1025 "TMCC3,ADD2,PCDH19,RTL9,OSBPL1A,ALCAM,SRPX,ARHGAP20,SYT13,ZFAT,CDC42BPA,MAP4K3,MYH7B,PPP4R4,CADPS,ZBTB10,SLC4A4,ATP2A2,BACH1,SYNJ2,ARHGEF7,CACNA1G,CACNA1B,CACNB4,P2RX6,DCLK1,MAGI1,CCPG1,CLGN,NPIPA1,PLAA,PPT2,TPP1,RAB26,CNR1,CNTN1,CREM,HAPLN1,ANKRD44,CLIP3,PNPLA8,BOC,HDAC9,ZNF337,LONRF1,IST1,JAKMIP2,DGCR5,KLHL3,WDR20,USP3,SLC25A18,AASDH,KLHL5,EGFR,PLEKHA1,DCTN4,NCALD,RASL12,F8,ZSCAN30,ZNF589,SUCO,MEX3B,PCYOX1,SYNCRIP,FOXO3,TMEM175,KHDRBS3,MEGF10,ZNF44,CHL1,GATM,GFER,BRD8,MCHR1,PCLO,ADAMTS13,GRM2,FAM19A2,RNF165,ADAMTS6,BACH2,MIER3,HMGCL,ZDHHC15,SHISAL1,LRRC25,CREG2,KIF5A,KIFC3,L1CAM,LIFR,MBP,MITF,MSR1,MXI1,MYO7A,ALDH1L2,NOVA1,SMIM11A,OPA1,PCSK5,ENPP2,PFKFB2,PIK3R1,CCSER2,MTRF1L,PURG,PPM1B,PRKAB2,GRAMD1C,MASP1,ZSCAN32,PTPRH,RBBP6,KHDRBS2,MSANTD2,ZMAT4,ZDHHC4,RGS4,RNASEL,ALG9,ARMH4,KIAA0895L,KCNIP3,ZFP30,SH3GL3,FERMT1,FBXO11,SEC31A,ST8SIA1,SLA,PEX26,DHX30,FAM214B,ZNF430,ARHGEF40,CCDC88A,SLC12A2,BTBD7,SNCA,MBD5,SNRPN,TMCC1,USP33,PDZD2,FNBP1,SP4,UNC5B,ZBTB43,ATP10B,ZSCAN29,SEPT8,CEP68,NSFL1C,COBL,FAM208A,TBCEL,TPCN2,TRIM2,RPGRIP1L,PUM2,TEK,DICER1,ACTR6,BHLHB9,BEX4,RIMBP2,PIK3R5,TPM1,CHST5,TTTY15,MTCH1,ATP6V0E2,MKRN3,LYPD6,ZFAND5,INTS3,SLC38A1,RNF103,FIP1L1,FAM47E,ST7,SOCS4" MicroRNA hsa-miR-23a*:mirSVR_lowEffct hsa-miR-23a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.33E-74 4.10E-70 4.96E-73 4.56E-72 191 1093 "SYN3,SYS1,ADD2,ADRA1D,C1QTNF1,SRPX,MARCH4,PPFIA4,EPB41L5,VAT1L,CPNE5,LGR5,AQP6,ZFYVE28,ARRB2,CCDC74A,TMEM108,SLC4A4,SLC2A11,DPY19L3,ATP6V0A1,ADGRB2,SEC11C,CFLAR,SCAPER,RAB29,KALRN,SPAG9,USP6,P2RX6,CBFA2T2,SEPT7,ZBED1,CACNA2D2,CFL2,C7orf61,RAB28,TPP1,MYL6B,DGCR9,SRP14-AS1,TOGARAM2,HAPLN1,TRIM69,CSF1,ARHGEF10,SUSD5,VAC14-AS1,KIAA0040,TBC1D5,INTS1,IST1,AIF1L,DNAL1,YTHDC1,JAKMIP2,PLPPR4,MTX3,DLX1,GRIN3A,DMD,HS3ST2,DTNA,ABCC5,E2F5,OPTN,SUGP2,AASS,SIRPB1,EZH1,TUBB3,CEP78,PPP1R1B,SEC24B,FGF1,OLFM1,TMEM164,EVL,SEMA4D,FLYWCH1,COQ5,WDR83,POMT1,DOT1L,MEGF10,GALNT15,RAPGEF6,LRRC37A6P,ALDH1L1,WASHC2A,TNRC6A,ZNF782,GRIA2,SOX21,RNFT2,CPT1C,CELF5,EID2B,KIAA1755,ZNF678,INPP5B,KCNN2,KIF5A,L1CAM,CAMK2N2,GPR155,MAN2A2,ZFYVE27,MARK1,XRRA1,RTL5,NF1,DNHD1,NTRK2,OGG1,TMIE,ZNF655,KCTD15,JAKMIP1,STRN3,LRP12,MINDY2,PKIA,PRKCB,HYDIN,PTPRD,PTPRH,TMEM231,USP47,ENOX1,ZDHHC14,MSANTD2,RFX2,UBR7,ZNF532,GSTCD,EPHA10,SPIN3,MEG3,ABCA11P,HSD11B1L,ATAT1,S100B,DGLUCY,ATXN2,TNFRSF19,SH3GL3,HKDC1,AMBRA1,FNDC3A,NLGN1,SLA,CCDC88A,CPEB4,IFT122,TEX2,SPART,SSTR1,ZC4H2,SSPO,ZSCAN29,NSFL1C,SYP,MTCL1,ZFP90,CUX2,ZEB1,PCDHB9,TNS2,FRYL,HIF3A,DICER1-AS1,PRRT1,R3HDM1,C9orf85,DOK6,RGMB,RUSC1,TSC1,HSPBP1,EIF4ENIF1,OSBP2,NDRG4,ZBTB38,SPIRE1,URM1,TRIM16L,PARP11,KAT6A,ADAMTS10,LAS1L" MicroRNA hsa-miR-340:PITA hsa-miR-340:PITA_TOP PITA 8.58E-74 4.80E-70 5.80E-73 5.34E-72 146 626 "CLK4,ZNF608,HECW2,PCDH19,OSBPL6,OSBPL8,ALCAM,TRMT9B,OGT,DPP10,LRCH2,LCORL,MAP4K3,GAS7,TMEM108,ADGRB3,SYNJ1,JAZF1,SGCE,CABP7,CALM1,CAMK2A,CAST,SPAG9,RUNX1T1,LDB2,KRIT1,MAGI1,CCPG1,ARHGEF6,AKAP5,CRY2,RIMS4,CNTNAP2,APPL1,PUM1,RIMS2,HDAC4,ZFYVE16,MAML1,SPOCK2,RHOBTB1,SACS,DMD,DYNC1I1,NR1D2,CDON,CPEB2,ABCC5,EDN1,SEMA3D,YAF2,TENM1,TMEM35A,ERBB4,MED12L,FGF13,UBE2E3,SLC37A3,NBEA,SMC2,ST6GALNAC3,STAU2,CHL1,LUZP2,CIT,TOX2,DHX35,IGF1,ZIC5,INSM1,LIFR,PACRG,MAP2,MAT2A,CHIC1,LRP1B,MEIS2,KITLG,MITF,MXI1,NEXMIF,NFE2L2,OCRL,GPR137C,PIK3C2A,RETREG1,XRN1,PDZRN4,STRN3,LRP12,RETREG2,SH3KBP1,PPP3CA,GRAMD1C,MTMR10,PTPRB,PTPRE,TMEM255A,FAM184A,RBBP6,REV3L,FIGN,RIC8B,ZFHX4,FNIP1,SUPT20H,SH3GL3,CPEB3,CHD9,EPN2,SLC11A1,SLC12A2,RCOR3,SOX11,SP4,TEX2,STAU1,NECAB1,SYT1,ANKRD28,CAMTA1,ADGRL3,FBXW11,TCF4,TRIM2,PUM2,ZFPM2,TIAM1,RIMBP2,KAT6B,TNS1,STXBP4,SSBP2,FAM155A,FLRT2,WIPF1,CADM2,PRDM8,RNF103,KCNAB1,PLSCR4,KAT6A,PHTF2,FRMD6,SENP7" MicroRNA hsa-miR-375:mirSVR_lowEffct hsa-miR-375:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-73 6.61E-70 7.97E-73 7.34E-72 180 973 "ABHD6,AS3MT,KLHL32,PLEKHH1,AGT,ADGRF5,SPOP,FAM135A,MAP4K3,PKP4,KCNAB2,PPFIA3,LGR5,TMEFF1,ZFYVE28,PDE8B,ZBTB10,GPR146,SCAPER,KALRN,USP6,RGN,LRRFIP1,MAGI1,NOG,CHN2,TPP1,QKI,FHL5,AKAP7,ARMC8,AKAP6,BAG4,CNRIP1,SEC31B,CDC42BPB,CREM,ANKRD44,CSNK1E,SOCS5,DZIP3,PUM1,CYBB,DOCK4,KATNAL2,ZFYVE16,MATR3,ARMCX4,GSDME,SNAP91,SPOCK3,WDR20,DMD,DPYSL2,DNM1L,EDIL3,EDN3,PHF20L1,EGFR,USPL1,RABEPK,SRRM1,PIPOX,ABCA8,ACSL4,FER,OLFM1,SUCO,PCYOX1,NELFCD,COQ5,EFCAB2,NBEA,APOPT1,KHDRBS3,AP4B1,FAM120B,IP6K3,TMEM8B,C15orf41,SULT1C4,AHDC1,PPARGC1A,HPGDS,GNAO1,STON1,LPAR4,STMN2,GRIA2,GRM8,SOX21,PSIP1,HNF4G,ZIC5,INSM1,JAK2,STXBP5,LAMA2,LIG4,HECTD2,MATN2,LRP1B,MEIS1,POC1B,MITF,ADAM22,NOVA1,NUCB2,OGG1,OXTR,PDE4A,CYTL1,NLGN3,PCDH18,PURG,PPP2R5E,PPP3CC,DCHS2,SNRK,CNTLN,PTCH1,ANKHD1,PTPRE,TTC13,ZMAT4,REV3L,PBRM1,RNASEL,ZFHX4,CARF,CCDC102B,NCBP3,CCDC112,SCP2,SH3GL3,CNKSR2,NAPB,ATF7IP,SLC22A4,DMRTC1,ANKRD36,LIMCH1,SNRPN,MYO16,MYCBP2,KDM4C,SAMSN1,SSTR1,ERBIN,NXT2,KLHL7,TACC1,MTCL1,CAMTA1,ZEB1,TCF12,PCDHB6,OBSL1,FAM200B,AKTIP,ERCC6L2,R3HDM1,TPM1,NPL,C9orf85,SGK3,RPRM,FAM155A,UBE2H,UBE3A,WRN,PCDH20,ZIC1,DNALI1,RNF103,DOCK8,TRAM2-AS1,KLHDC1,FRMD6,NETO1" MicroRNA hsa-miR-4286:mirSVR_lowEffct hsa-miR-4286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-73 7.49E-70 9.02E-73 8.31E-72 201 1213 "SYN3,RNF157,ADD2,BRAP,PTCHD1,RTL9,OSBPL8,BEGAIN,OGT,PI16,CCDC146,SUGT1P4-STRA6LP-CCDC180,UPRT,SHROOM2,SEMA4G,PRX,CCDC74A,PCDHGB4,RASL11B,ATP1B3,ATP6V0A1,FUBP1,CACNA1I,CA4,SLC25A14,SPAG9,CBLN1,SCARB1,C1orf52,KCNAB3,TBRG4,CHN2,CPNE6,RAB33A,PLAA,PPT2,IGLON5,SLC4A8,SLC35F1,ANKRD44,TRIM69,CS,PDE4DIP,RUBCN,CYBB,ZFYVE16,GIT2,DDX46,POM121,SNAP91,PARD6A,WDR20,CHRDL1,CPEB2,DOCK2,DPP6,ACOT8,E2F5,EDN1,SEMA3D,TNK2,C3orf18,RCAN2,CDKL3,EZH1,FCGR1A,FGF1,FLNC,NOP56,ATP2C1,CELF1,ABLIM2,FYB1,NEURL4,ZNF274,ERAP1,C15orf41,GGT5,GLUL,TDRKH,BTN2A1,TOX2,PADI2,BACH2,LRRC75A,SHISA6,NKD1,RBPJ,IL6R,INPP5B,KCNJ5,PIK3AP1,CHIC1,MEIS1,MIA2,SCAMP5,GIT1,DBNL,MXI1,LYRM9,NBL1,NEK1,NNAT,NTRK2,NTRK3,CLDN11,OXTR,ZNF827,TREM2,PCDHGC3,PFKFB2,PFKFB3,ZNF655,SNX10,GPSM2,PLCD1,PNMA3,POLR2F,PPP2R2C,PRKAB2,MASP1,BCAS3,GDPD2,CNTLN,MTMR10,PID1,TMEM255A,ROGDI,ZNF493,GAL3ST4,DPF2,RFX3,TMLHE,EPHA10,MEG3,ST6GALNAC6,KCNIP3,ATXN2,ATXN7,CASC3,GALNT10,COPZ1,FAM102A,PPM1E,ST6GAL1,SYBU,NLGN1,SLA,DHX30,ARHGEF40,SLC12A4,NAPB,ARFGAP1,IFT122,USP33,TEX2,NFASC,NKAIN2,ELOVL4,SEPT8,PHLDB1,SEPT3,NUDT10,SLC37A2,TACC1,FAM208A,PDLIM2,AGTPBP1,KLHL4,SIN3B,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NSD1,USP32P1,C18orf54,BEX4,SYNPO2,METTL3,DCBLD1,PLEKHH2,ZNF781,ATP6V0E2,ZNF70,CRB2,ZNF154,SPIRE1,PPP1R3F,ITM2C,PCBP4,UBE3B,TMEM63C" MicroRNA hsa-miR-154*:mirSVR_highEffct hsa-miR-154*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-73 7.73E-70 9.31E-73 8.57E-72 183 1007 "NCKAP5,ACTN1,PWWP2A,AP2A2,ZNF608,HECW2,AGT,NME5,OSBPL6,ARHGAP20,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,PPP4R4,RASL11B,SLC4A4,SEC11C,CFLAR,CALB2,CAST,CCK,LDB2,C1orf52,CDH2,ZMYM4,RCBTB2,SRSF11,NGEF,ABCG2,TMEM184B,CNR1,COL9A1,ABI3BP,CRHBP,GDA,APPL1,USP6NL,DOCK4,GAPVD1,LIN54,KIAA0586,DAPK1,YTHDC1,ZBTB24,MYEF2,ZC3H11A,PLPPR4,SGSM2,USP3,PDCD6IP,DTNA,HIPK3,FAM13A,MRO,SIRPB1,ABCA8,CEP78,GORAB,SUCO,MEX3B,VTI1B,AGAP3,NBEA,ATP2C1,AP4B1,GALC,NEU3,TUBA8,PPARGC1A,COPS8,ZNF638,FERMT2,LNX1,GPD2,TDRKH,GPER1,PSIP1,MAP4K5,HMGCR,HNMT,SMAP1,ZIC5,LRRCC1,INSM1,KCNN2,KIT,HECTD2,MARK3,MEIS1,MEST,AFDN,BLOC1S2,LOC100128398,CLDN11,PDE4D,KCTD15,PDZRN4,TRHDE,ING3,EPB41L4B,PPM1B,PPP2R5E,PRKACB,PKIA,PRPSAP2,MTMR10,PTPN13,EML5,MARCH1,CEP97,OXR1,RASGRF2,RBBP6,ZDHHC14,RDX,MORC4,RFX3,TMLHE,CARF,PNMA8A,PCMTD2,ARMH4,HUNK,ZNF568,AP1AR,ATXN2,FAM81A,SLC9A5,ZNF334,ATF7IP,ANKRD36,LIMCH1,MBD5,SNRPN,PDZD2,KDM4C,RBM26,SPART,SSTR2,ERBIN,ZSCAN29,NEK4,SEPT8,SYNE2,VPS13A,NUDT10,SYN2,COBL,MTCL1,PJA1,MLST8,ZEB1,RPGRIP1L,PUM2,SIRT1,ITGB3BP,AP4E1,AKTIP,TP53BP1,CDK20,SYNPO2,RUNDC3B,STXBP4,SSBP2,SGK3,UGT8,GUSBP1,ZFP37,ZNF711,ZNF19,ZNF32,KCNT2,FSTL5,EML6,ANKS1B,ZNF225,CADM2,EVI5,TMEM178A,TRIM16L,FAM13C,PHTF2,JMJD1C,IFT88" MicroRNA hsa-miR-1826:mirSVR_lowEffct hsa-miR-1826:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-73 8.17E-70 9.82E-73 9.04E-72 216 1395 "KCNH8,ADCY6,ADD1,ADD2,SLC24A4,AP2A2,HECW2,KLHL13,WDR35,OSBPL8,CC2D2A,HFM1,SEMA6A,MAP4K3,MAGEE2,NT5C3B,USP37,LGR5,CDC14B,PPP4R4,ARSE,ALDH7A1,ADAM23,BCHE,RGS11,CFLAR,SYNJ1,BAIAP3,CA8,CACNB4,CALM1,DCLK1,DLGAP2,RCBTB2,CHN2,SRP14-AS1,HECTD1,SLC4A8,ABI3BP,RCHY1,ZNF521,SLC35F1,CPS1,AKAP12,HAPLN1,GDA,KIAA0040,CTH,CCDC144A,HDAC9,ARHGAP32,RIPOR2,ARHGAP24,ZNF337,LIN54,DGKB,GIT2,JAKMIP2,MFAP3L,KIAA0753,ALKBH8,DMD,SLC12A6,CASP8AP2,DPYSL2,WDPCP,SUGP2,KMT5B,RASA4,ASB3,EIF4G2,PLEKHA1,ING4,GPHN,MRPL37,MRVI1,F8,FAM198B,SCML2,GORAB,SEC24B,MEX3B,SEC23B,PCYOX1,ANKFY1,EFCAB2,CELF1,ST6GALNAC3,NSG1,DLL3,STAU2,GABRG1,GLI2,LUZP2,FERMT2,LNX1,LILRB4,FUT10,GPR12,ZNF496,ADAMTS6,IRAK3,ZHX1,ARHGAP36,IL6ST,ITGA7,KCNN2,STXBP5,KTN1,HECTD2,PIK3AP1,MBP,MID1,AFF1,AFDN,ADAM22,MXI1,MYO6,ZC3H12B,IDNK,NPR2,OPA1,CNTN3,PAX6,PDE4A,OLA1,XRN1,PURG,PRIMPOL,PSAT1,DIRAS2,RELN,WBP1L,DEF8,QRICH1,PIGG,CNTLN,BDNF-AS,IQSEC3,SUSD4,RBBP6,GTDC1,RGS4,MRPS18A,CCDC82,ROBO2,CCDC25,RORB,ELP2,MCMBP,MEG3,KCNIP3,TRAPPC13,MAPK12,CSRNP3,SCN8A,FNIP1,FOXRED1,ZFP30,KIF21A,FNDC3A,ST6GAL1,SLA,SLC9A5,KBTBD4,SLC12A2,ELMO2,MBD5,LMBRD1,SNRPN,FAM219A,SOX3,SOX11,HECW1,KDM4C,PEG10,IQSEC2,DDN,PDLIM2,ADGRL3,MGRN1,ATMIN,TCF4,DOCK9,DICER1,ZFPM2,ITGB3BP,PIK3R5,TP53BP1,C9orf85,SMUG1,STXBP4,PPIL6,TSN,TTTY15,TTC3,FLRT2,VLDLR,ZNF23,ZNF24,TMEM237,SMARCAD1,INTS3,EVI5,RNF103,TUBA1A,VPS35L,KCNAB1,AMN1,MARCH8,UBE3B,TIGD6,FXR1,DPF3,SOCS4,FAM198A" MicroRNA hsa-miR-4259:mirSVR_lowEffct hsa-miR-4259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-73 8.81E-70 1.06E-72 9.74E-72 223 1483 "RALGAPA1,DGCR6,ASIC1,CLK4,ADD2,BRAP,KIAA1211,FAHD2CP,DPY19L2P4,CC2D2A,ADGRF5,PCDH10,ZNF687,DPP10,PI16,APLP1,PHYHD1,VAT1L,PRX,ARNTL,CDK13,TMEM108,SLC2A11,ATP6V0A1,MYOM1,TTLL9,ADAM15,SEC11C,BMP7,SYNJ1,CASTOR3,MTMR3,CALB2,CAMK2G,CAST,METTL6,ENTPD6,MAGI1,SRSF11,ASIC3,EPS15L1,CPNE6,FAM19A5,CNN3,ARHGEF6,PCYT1B,AKAP6,LETMD1,SMARCAL1,CRMP1,NCOR1,CSF1R,SEC24C,ERC2,PHF14,PPP6R2,FAM131B,TCAF1,ZNF337,KCTD8,DGKB,B3GAT3,GRIN3A,DNM1,HS3ST2,USP3,CPEB2,DNM1L,EDN1,PHC2,FCF1,HEYL,YAF2,CELSR3,EGFR,MRO,RABEPK,NCALD,IGSF6,MRPL10,ANKMY1,SIRPB1,MRVI1,FAM198B,ACSL4,FGF11,POLK,SYNCRIP,NELFCD,FAM49B,BRSK1,ALDH1L1,CYP46A1,GGT7,GHR,MALT1,MSL3,GPT2,TDRKH,PLCD4,SERP2,GRIN2D,GRM2,RNF165,ZBTB45,AP4S1,FAM107A,SLC2A6,SYNPO,ZDHHC15,IRF8,SOWAHA,DISP2,NME9,ITGA7,KIF5A,MAP6,MBD1,MSR1,MT1M,HS6ST3,MYO7A,P2RY13,NEK1,NFE2L2,VWA2,NOVA1,NOVA2,CCSER2,PLCB2,NECAB2,PCDHB17P,PPP2R5E,NKAIN4,MAPK4,EPDR1,MAPK7,RAD51D,FAM184A,RBBP6,ZDHHC14,MSANTD2,PRRT2,RGS12,SLC25A36,RIC8B,CARF,PNMA8A,ROBO2,SNX22,NEK11,EPHA10,SPIN3,GLDN,ABCA11P,ZNF331,AP1AR,SEMA6D,CSRNP3,SCN2B,SCN8A,SCP2,COPZ1,FNDC3A,CCDC92,DZIP1,SLC6A8,ARHGEF40,SLC11A1,NAPB,EPC1,MAST1,LIMCH1,SNCA,CMTR2,KDM4B,DOP1A,ZSWIM8,HECW1,PEG10,DDN,ATP10B,CLSTN2,ITPRID2,STAC2,STXBP1,NECAB1,SYP,MLST8,CUX2,FAM189A1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,THRA,ASXL3,RGMB,SMUG1,AMACR,GORASP1,OSBP2,WIPF1,CLDND1,XRCC4,NDRG4,ZNF177,ZNF195,SLC30A4,MFF,DNALI1,ADAMTS9,TMEM178A,NAV3,WNK3,DOCK8,KAT6A,FBXO36" MicroRNA hsa-miR-645:mirSVR_lowEffct hsa-miR-645:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.89E-73 1.06E-69 1.27E-72 1.17E-71 184 1020 "EMILIN3,GALNT13,PWWP2A,KLHL13,TBC1D14,WDR35,USP35,SUGT1P4-STRA6LP-CCDC180,APC,BCAS1,LGR5,CADPS,MARCH3,ZBTB10,DYNLL1,ZNF583,SLC2A11,ALDH7A1,BBS2,BMP7,BMPR1B,SCAPER,SGCE,RAB29,CA8,C1orf52,PPT2,FAM19A5,QKI,SRP14-AS1,COL4A5,SLC4A8,CNRIP1,RBM39,AKAP12,CRY2,SNCAIP,CSNK1G3,IPCEF1,PDE4DIP,SLITRK5,RIMS2,CYBB,KCTD8,DGKB,DGKG,DBN1,SPATA2,ZBTB24,SPOCK3,CD99L2,DMTF1,SLC25A18,DRP2,DNAJB6,ABCC5,E2F5,E2F6,EDN3,HIPK3,CNNM1,RASGRP1,PHF20L1,USPL1,VPS13B,EPB41,RASL12,FAM198B,ACSL4,PTK2B,RACK1,FKTN,ZNF589,SEC24B,GTF2IRD2,UBE2E3,EVL,COQ5,C2orf88,APOPT1,ATP2C1,FAM120B,KIAA1841,GCK,SESN1,TCERG1,GLUL,ADGRA3,PRUNE2,LPAR4,GRB10,CIT,FRMD5,MAN1B1,MIER3,HLF,HMGCL,HNMT,ZDHHC15,NKD1,NME9,LMO2,GPR155,MAT2A,LRP1B,MEF2C,THYN1,NFE2L2,CNOT4,SLC11A2,SMIM11A,SETD4,TBC1D25,PDCD2,CCSER2,PPM1B,MAPK9,MAPK10,BCAS3,VPS13C,PPP2R3C,ZDHHC14,RFX3,PRIMA1,MRPS18A,RIC8B,ALG9,YY1AP1,SPIN3,KIAA0895L,PTGR2,S100B,SEMA6D,SATB1,LRFN5,SCN7A,PRCD,CASC3,MRAS,PPM1E,AMBRA1,PEX26,DHX30,SLC11A1,ATF7IP,DOP1A,BDP1,ZSWIM8,PEG10,SPART,ATP10B,CLSTN2,POGZ,ITPRID2,CEP68,DIP2A,ADHFE1,SUPT5H,SLC37A2,NAT16,DICER1-AS1,RASD2,ZNF346,RUSC1,TTTY15,CLIP2,LAT2,TRIM9,MKRN3,ZNF138,ZNF142,ZNF154,ZNF213,MEIS3,UPF3A,GDPD5,SEMA3B,FAM47E,SMIM8,ADAMTSL3,SNX14,IFT88,NETO2,PRRT4" MicroRNA hsa-miR-514b-5p:mirSVR_highEffct hsa-miR-514b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-73 1.31E-69 1.57E-72 1.45E-71 190 1089 "DPY19L2P4,HECW2,ALCAM,SRPX,OGT,PPP4R4,CDK13,MARCH3,EIF4G3,N4BP2L1,LINC00847,BCL7A,CFLAR,DST,CALM1,KALRN,VXN,ZNF501,LRBA,SEPT7,CCPG1,QKI,MAP4K4,ARMC8,FAM171B,PREPL,RBM39,RNF14,MROH8,CSNK1G3,SOCS5,RIPOR2,KIAA0586,DGKB,TMEM170A,GIT2,SACS,FAM107B,DYNC1I1,CPEB2,DPH1,RCAN1,FAM78B,EDN3,EDNRA,FCF1,FRY,PHF20L1,SUGP2,STX2,SIRPB1,EXTL2,F5,FAM198B,ZNF461,ACSL4,GORAB,POLR1B,SYNCRIP,NBEA,SMC2,CELF1,ST6GALNAC3,MSANTD4,OGA,MEGF11,GATM,PCDH17,LYVE1,BRD8,GPR75,CBX1,DCLK2,TMEM121B,DIDO1,SERP2,BTN2A1,PSIP1,RNFT2,FAM222A,TOX2,ARHGAP36,IDH3A,NCOA7,MBNL1,TM6SF1,MMP16,ZNF680,ZNF92,MYO9A,NEFM,NEFH,NF1,VWA2,CNOT4,NOVA1,GNG2,OLA1,NALCN,CCSER2,SNX10,PRIMPOL,MINDY2,PPM1B,RASGEF1B,MASP1,CNTLN,TMEM260,PTX3,PID1,OXR1,ZDHHC14,RET,ERI2,RFX3,PBRM1,ZFHX4,CARF,GSTCD,CCDC25,RPL15,ATAT1,KCNIP1,CLIP1,ATXN7,FNDC3A,WDR37,PEX26,PPP4R3A,FAM214B,SLC6A8,CCDC88A,NAPB,SNCA,ZNF415,BDP1,KDM4C,RBM26,ATP10B,PBLD,TROVE2,CLSTN2,NECAB1,DNAJC9,SYPL1,SYT1,PJA1,ADGRL3,AGTPBP1,KLHL4,ZEB1,SYNE1,DOCK9,GPRIN3,PMS2CL,ITGB3BP,AP4E1,AKTIP,ARL10,TIAM1,TPM1,NPL,RGMB,RUNDC3B,AMACR,TSN,SGK3,RPL7L1,UBE2H,UBE3A,PLEKHH2,RICTOR,ZNF711,ZNF708,MICU3,FSTL5,ZNF189,ANKS1B,PRDM10,HPS4,CIAPIN1,KCNAB1,RGS7BP,AMN1,DOCK8,PHTF2,TIGD6,FXR1,NETO2,NETO1" MicroRNA hsa-miR-640:mirSVR_lowEffct hsa-miR-640:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.48E-73 1.39E-69 1.66E-72 1.53E-71 208 1301 "RALGAPA1,CLK4,KLHL32,BRAP,ZNF608,WDR35,TAOK1,CARNS1,SUGT1P4-STRA6LP-CCDC180,SHROOM2,IGDCC4,RGS20,NCOA1,ATP1B3,N4BP2L1,DPY19L3,TTLL9,BBS2,RGS9,CFLAR,ARHGEF7,JAZF1,CACNA1G,CA4,CA12,PTBP2,HIP1R,CBS,CBFA2T2,DGKI,AP4M1,CDH2,DCLK1,ZMYM4,SRSF11,MS4A7,RAB28,LETMD1,AKAP5,RCHY1,CLIP3,PDE4DIP,CTH,MYADM,RASSF2,MAML1,DGKB,ARMCX4,DDX46,SPOCK3,SGSM2,TMCC2,RAB39B,DMTF1,SLC25A18,ARRDC4,FAM78B,TOM1,DNAJB6,KRBA2,RASGRP1,TMTC1,PHF20L1,MBNL2,PAN3,SCML2,SLC9B2,GTF2IRD2,AMOTL2,FHL1,POLK,SUCO,FLT1,SLC37A3,ERGIC3,STAU2,ALDH1L1,GCNT2,COPS8,DBF4,STARD3,ZNF638,LUZP2,DCLK2,MCHR1,PCLO,GRB10,PLCD4,ADAMTS6,IRAK3,HNF4G,ZDHHC15,SHISA6,ICA1,IL6R,CDH20,GATD1,STXBP5,LIFR,SYTL4,ZNF667-AS1,TM6SF1,MEIS1,KITLG,PPM1L,MMP16,ZNF680,DBNL,MSR1,MYO6,NACA,NFYA,SLC11A2,NRCAM,NUCB2,OXTR,PCSK1,PDPK1,XRN1,JAKMIP1,ZNF426,MTRF1L,PURG,RETREG2,PPM1B,PPP1R1A,CCDC144B,LRRN3,PRKACB,SLC26A11,MASP1,DEF8,PTN,ZSCAN32,ACSM5,FAM66C,ZDHHC14,CRTAC1,DPF2,RET,RGS12,SLC25A36,RIC8B,PBRM1,ATP8B4,HSD11B1L,ATXN2,ATXN7,LRFN5,SCP2,FNIP1,STUM,MRAS,ASAP3,CHD9,FHOD3,ST6GAL1,NUBPL,SLA,PPP4R3A,KANSL3,ARHGEF40,TET1,MYH15,MBD5,KIF13A,SNRPN,FAM126B,BDP1,NMNAT2,ZC3H13,CDK19,TSPYL2,POGZ,SEPT8,DIP2A,ADHFE1,SYNE2,NUDT10,SYN2,CAMTA1,TAL1,FBXW11,SATB2,TPCN2,NAT16,DICER1-AS1,ARL10,TK2,TMPO,R3HDM1,NPL,SMUG1,TRPS1,RUSC1,TTC3,FLRT2,GUSBP1,ZBTB14,ZNF24,LAMP5,STOX2,PRDM8,RNF103,VPS35L,ST7,SOCS4,SPATA13" MicroRNA hsa-miR-323-5p:mirSVR_lowEffct hsa-miR-323-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-73 1.41E-69 1.69E-72 1.55E-71 195 1147 "ABHD6,NDRG3,KLHL32,RNF157,UNC5A,SPOP,MARCH4,ALK,MYH7B,PKP4,KCNAB2,CDK10,TMEFF1,ARRB1,RGS20,PLA2G4C,ASGR1,DPY19L3,BARD1,KSR1,FUBP1,GYG2,DDR1,KALRN,VXN,SRSF11,SOCS6,CHN2,FAM19A5,CNTN1,IQCK,FAM149A,ABI3BP,TOGARAM2,SLC35F1,CDC42BPB,SH2B1,GDA,CLIP3,RGS6,SIPA1L1,VCAN,ARHGAP24,LONRF1,IST1,DGKG,POM121,SV2B,SGSM2,SEC16A,CHRDL1,DMD,DNM1,DYNC1I1,TOM1,DNAJB6,EDNRA,ANKRD46,EGFR,SRRM1,DENND4A,EZH1,HSPA12B,ABCA8,TAOK3,DLC1,ST3GAL6,STRADA,KAT8,GORAB,SLC9B2,FGF13,BAIAP2,AGAP2,ZBED3,NSG1,GAD1,GFER,BRD8,CRCP,TOX3,MSL3,GNAL,PRUNE2,PLCD4,SPACA9,GRM2,BTN2A1,RNF165,AP4S1,AGBL5,LRRC75A,SHISA6,EID2B,IFI16,MYLK2,ZIC5,LRRCC1,ITGAM,KCND2,LIMS1,PAXBP1,MBNL1,PPM1L,COL28A1,PTOV1,MYCN,MYO7A,ZNF862,NCAM2,NFE2L2,NINJ2,NNAT,SMIM11A,NTRK2,NUCB2,OCRL,GLIPR1L2,PCSK5,SLC25A23,ZNF426,PURG,SCHIP1,PPP1R1A,RANBP3L,MAPK7,MAPK9,PSD,WDR25,RAD51D,ZCWPW1,ROGDI,MSANTD2,RET,GTDC1,MRPS18A,CCDC82,GSTCD,ROBO2,CCDC102B,SNX22,NEK11,KIAA0895L,TCP11L1,MEG3,SATB1,SCN8A,PRCD,KIF16B,PKNOX2,ELMO2,INAVA,MBD5,MYO16,SP4,PEG10,ZC3H13,TSPYL2,ATP10B,POGZ,ITPRID2,NKAIN2,SEPT8,RHBDL3,COBL,FAM208A,WSCD1,TCF4,RPGRIP1L,PCDHB3,SLC44A1,TNS1,ZNF346,PDSS1,RUSC1,UBTF,MTCH1,PLPPR2,WIPF1,CLDND1,LGI4,ZNF154,POLR3H,AMZ1,ZNF213,RNF103,ADAMTS9,NAV3,PCBP4,ST7,UBE3B,KAT6A,CASC15,FAM219B,ST8SIA2" MicroRNA hsa-miR-1289:mirSVR_lowEffct hsa-miR-1289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.84E-73 2.15E-69 2.56E-72 2.36E-71 203 1244 "NCKAP5,PTCHD1,OLMALINC,OSBPL6,C1QTNF3,UNC79,FAM135A,LRFN1,ANK2,SEMA7A,UPRT,PPFIA3,CDK10,TMEM108,EIF4G3,TTLL9,ADGRB2,BBS2,KSR1,ARHGEF7,NAE1,RAB29,PTBP2,CAMK2A,VXN,HIP1R,CBLN1,SEPT7,ASIC3,CHN2,PPT2,MAP4K4,CNTFR,IQCK,LETMD1,COL11A2,TBPL1,ZNF385A,SLC35F1,CRY2,HINFP,CS,ARHGEF10,UBXN2A,CTH,KATNAL2,ARHGAP24,TM9SF4,IP6K1,HEPH,MYEF2,C2CD2L,RHOBTB1,TMCC2,KIF19,RPS6KL1,DPH1,CASP8AP2,DNM1L,EBF1,HEYL,YAF2,APH1A,EGFR,GOLGA7,KCTD3,CERCAM,ELN,COQ7,STX2,SRRM1,DENND4A,NCALD,KATNAL1,MRVI1,HSPA12B,CORO2B,FCGRT,OLFM1,FGF12,BAIAP2,FHL1,AGAP2,SLC37A3,AFF2,AKAP3,ST6GALNAC3,TVP23A,FYB1,MEGF10,GAD1,TUBGCP4,CYP46A1,GGT5,TTBK1,TCERG1,GLI2,DCLK2,WDFY3-AS2,CCDC184,STON1,GRB10,ADAMTS13,GRIK5,FAM19A2,RNF165,AP4S1,PSIP1,GUCY1B1,SYNPO,NEGR1,CPT1C,SHISA6,SMAP1,EID2B,ITPKA,KCND1,L1CAM,LAMA2,SYTL4,CLEC18A,MARK1,MIA2,AFF1,MSR1,MYO9A,NF1,NME4,NOVA1,PDE1B,ENPP2,CCSER2,XRN1,PKM,PMP22,SDK2,EPB41L4B,RANBP3L,PKIA,HYDIN,CYBC1,PSMA6,WDR25,TMEM260,ZSCAN32,PTPRD,ZSCAN2,ZNF793,ROGDI,TRIM68,PRRT2,EXD2,ROBO2,NEK11,ATAT1,RTN1,ATXN7,SCP2,STUM,FOXRED1,SLC12A2,ATF7IP,SLC22A4,MAST1,SMARCC2,FAM219A,ZBTB43,NFASC,CLASP2,POGZ,ITPRID2,ADHFE1,SYNE2,ARC,MLST8,CUX2,SZT2,NAT16,SLC19A3,TNS2,HIF3A,MTMR14,TMPO,PRRT1,TNS1,TPM1,CDK20,C9orf85,SMUG1,TSC1,OSBP2,ZBTB14,ZIC2,ZBTB38,ZNF213,SLC30A3,GDPD5,LINC02210,PRDM8,UBE3B,RNF170,SOCS4,PRRT4" MicroRNA hsa-miR-298:mirSVR_highEffct hsa-miR-298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.09E-73 2.29E-69 2.73E-72 2.51E-71 199 1197 "ACTN1,NDRG3,NDRG2,CCDC85A,ADD1,PTCHD1,ZNF608,HECW2,ALCAM,ARHGAP20,LTBP4,ANK2,SEMA7A,PARG,MADD,ARNTL,NCOA1,DYNLL1,ATP6V1G2,BARD1,MPDZ,ST3GAL5,ARHGEF7,CA8,PTBP2,CAST,KRIT1,ARHGEF2,L3MBTL4,DLGAP1,SRSF11,SLIT2,TPP1,CNTN1,LETMD1,SLC4A8,TOGARAM2,FAM171B,CREM,RGS6,OSBPL3,SOCS5,PDE4DIP,CYBB,RIPOR2,MATR3,IST1,DCTN1,MYEF2,RHOBTB1,PLPPR4,SV2B,SPOCK3,ZNF582-AS1,USP3,CPEB2,DTNA,EDNRA,EGFR,EIF4G2,COPS4,TENM1,TMEM35A,RABEPK,CEP85L,ADGRV1,F5,PRMT5,SLC9B2,POLR1B,FGF13,FHL1,SUCO,TMEM107,PDLIM5,STAMBP,CAMKK2,ATP2C1,ST6GALNAC3,CSPG5,NSG1,AP4B1,MPP6,ZMAT1,HRASLS5,IP6K3,GATM,MSTN,PPARGC1A,GLI2,RAB30,KCNMB4,ZNF782,FUT10,STON1,LPAR4,GRIA2,SPACA9,PRDM5,RNFT2,SLC2A6,IRAK3,ARHGAP36,MIER3,VSIG4,ZDHHC15,LRRCC1,ZNF678,NME9,KCNN2,ZNF667-AS1,MAP4,MATN3,MBNL1,MEIS1,COMMD5,MYO9A,BEX5,SLC11A2,NTRK2,NUCB2,OGG1,OPA1,PCDH9,PDE4B,ABCB1,FAM218A,KCTD15,EXOSC10,CEP41,EPDR1,GRAMD1C,PRPSAP2,SAMD9,GDPD2,SNRK,ELOVL2,PTPRG,FAM66C,NWD1,DPF2,MORC4,PRIMA1,LGI2,CARF,ELP2,TCP11L1,AP1AR,CASC3,TRA2B,FERMT1,FBXO11,CCDC92,PPP4R3A,ATF7IP,MYH15,RCOR3,IFT122,ANKRD36,MBD5,PDZRN3,KDM4C,CLASP2,CLSTN2,POGZ,NKAIN2,ELOVL4,RGL1,SYNE2,AGTPBP1,TBCEL,FBXW11,ZEB1,RPGRIP1L,TCF12,PCDHB4,GPRIN3,FAM200B,DICER1,ITGB3BP,MTMR14,ACTR6,TPM1,RUSC1,KCNE5,ZFP37,ZNF138,AMZ1,SH3GLB2,SMARCAD1,DNALI1,STOX2,KCNAB1,RGS7BP,RTN4,FRMD6,NETO2,FAM198A,SPATA13" MicroRNA hsa-miR-125a-5p:mirSVR_lowEffct hsa-miR-125a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.75E-73 2.66E-69 3.16E-72 2.91E-71 225 1517 "ACADM,ACHE,SYS1,NDRG3,ADD1,LRFN2,BEND6,MTUS1,RTL9,TXNDC16,CC2D2A,MARCH4,AMPD2,PI16,PKP4,KCNAB2,APC,UPRT,TNRC6C,AQP6,SPTBN4,SLC4A4,SLC2A11,DOCK11,CFLAR,KSR1,SYNJ1,SCAPER,CACNA1B,DDR1,ISPD,ARHGEF1,SCARB1,ENTPD6,ARHGEF2,DCLK1,L3MBTL4,CBARP,RAB33A,RAB28,ARHGEF6,ANKRD35,SUMF2,MYRIP,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,SIPA1L1,APPL1,CTH,GREB1,FAM131B,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,HEPH,RUSC2,ZC3H11A,RPS6KL1,DPH1,RCAN1,DTNA,DTNB,ABCC5,PHC2,CNNM1,PHF20L1,TMEM132E,PLEKHA1,MRPL10,ANKMY1,SCML2,FCGR1A,STRADA,ZNF589,FER,PRKAG2,SMC2,HHIPL1,AP4B1,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,USP19,GGT7,CRCP,TCERG1,ZNF638,LOXL3,LILRA2,CCDC184,LPAR4,TMEM121B,PCLO,GRB10,GRIA2,SPACA9,RASSF8,PADI2,MAN1B1,TNFAIP8L3,SYNPO,HMGCR,HNF4G,NKD1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KHK,KIF5A,KIFC3,SYTL4,HECTD2,LSS,MAP2,MAP6,ADAM11,MIA2,MSI1,MYO7A,NEFM,NUCB2,IGSF11,DPY19L2P2,ZDHHC8,ZNF655,RETREG2,POLG,MINDY2,MAPK10,VPS13C,CNTLN,PTH1R,PTK2,PTPRD,PTPRE,C1orf109,FAT4,ZDHHC14,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,SNX22,STK32B,EMID1,LRRK2,MEG3,SCN2B,SCP2,CASC3,KIF16B,MYO18A,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,LGI3,ABTB1,SMARCA4,ANKRD36,SNRPN,DOP1A,GLT8D1,ZC3H13,SPTB,NFASC,SS18,SSPO,ELOVL4,ADHFE1,SYN2,SLC37A2,TACR1,SATB2,RPGRIP1L,PMS2CL,DICER1,GPR161,AKTIP,BHLHB9,LRRC8A,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,FLRT2,BCL2L13,ELFN1,CRB2,LYPD6,TMEM198,EML6,STOX2,ADAMTS9,SEMA3B,SLC17A7,PLSCR4,PARP11,UBE3B,TMEM63C,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-1261:mirSVR_highEffct hsa-miR-1261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-73 2.96E-69 3.52E-72 3.24E-71 182 1004 "PWWP2A,ZNF608,HACE1,OSBPL1A,FAM135A,SYT13,LCORL,KCNAB2,UPRT,TMEFF1,ZBTB10,TMEM108,EIF4G3,ZNF583,SLC2A11,ADAM23,ST3GAL5,LURAP1,CALB1,PTBP2,SLC25A14,SPAG9,USP6,SEPT7,CCPG1,CFL2,SRSF11,SOCS6,CHN1,TPP1,CLTC,ANKRD44,GDA,CSF2RA,OSBPL3,VCAN,DCAF4,TCAF1,RIPOR2,MAML1,DAPK1,PABPC5,ARMCX2,YTHDC1,MYEF2,DMD,CPEB2,E2F6,EDNRB,SEMA3D,EGFR,EIF4G2,PLEKHA1,TUBD1,RASL12,EXTL2,EYA1,FAM198B,TMEM132C,CEP78,POLK,JKAMP,NBEA,ZBED3,ATP2C1,ADAM28,MALT1,TOX3,KIAA1958,FUT10,PCLO,PSIP1,MIER3,GABARAPL2,HNMT,NEGR1,SMAP1,ZNF678,CREG2,STXBP5,TTYH2,LIMS1,LMO2,HECTD2,NCOA7,MEIS1,PPM1L,POC1B,MSR1,MXI1,NF1,NFE2L2,P2RX7,GLIPR1L2,ETFRF1,PDCD2,PIK3R1,ZNF655,SNX10,STRN3,PRKAB2,PRKCB,GRAMD1C,PTK2,TMEM260,PTPRD,ACSS3,OXR1,RGS4,SLC25A36,RNASEL,CCDC82,CARF,NEK11,ZC3H14,GLDN,RPS20,KCNIP1,RYR3,FAM192A,SEMA6D,SATB1,FNIP1,CASC3,SCAF8,ZFP30,CHD9,CCDC92,FAM81A,KDM4D,SEPHS1,CCDC88A,KBTBD4,BTBD7,SLC22A4,ZFP1,CXXC4,MAST1,TMCC1,UNC5B,RBM26,ATP10B,POGZ,ITPRID2,ERBIN,NEK4,SEPT3,KLHL7,TACR1,KLHL4,CUX2,ZEB1,TRIM2,USP32P1,FRYL,RNF216P1,C18orf54,AP4E1,ZNF34,HEY1,LRRC8A,USP1,ZNF709,WIPF1,ZNF781,GUSBP1,KCNK12,ZBTB14,ZIC2,TCEAL7,FSTL5,EMSY,VPS35L,NAV3,RGS7BP,FZD3,DOCK8,KAT6A,CASC15,TRAM2-AS1,RNF170,NETO1" MicroRNA hsa-miR-34c-3p:mirSVR_lowEffct hsa-miR-34c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.37E-73 3.00E-69 3.57E-72 3.28E-71 214 1380 "CLK4,SYS1,KLHL32,TMCC3,GALNT13,ADD2,ADRB2,BEND6,C1QTNF3,ALCAM,ALK,CDC42BPA,DPP10,LCORL,PARG,MADD,CASK,ARRB1,CDK13,PDE8B,DNAH17,DYNLL1,ATP6V0A1,BACH1,ADGRB2,BMPR1B,SYNJ2,FUBP1,THSD7A,KCNAB3,DCLK1,MAGI1,CACNA2D2,FOXN3,ABCG2,FHL5,FAM149A,COL4A5,SUMF2,AHCTF1,MYRIP,CLOCK,ENTPD4,PDE4DIP,KIAA0040,ERC2,GREB1,ARMCX2,YTHDC1,MFAP3L,WDR20,GRIN3A,NR1D2,CASP8AP2,PDCD6IP,ECM2,DNAJB6,EDN1,IRAK4,TMEM35A,SRRM1,KATNAL1,CEP78,FECH,PRKAG2,SYNCRIP,FLYWCH1,C2orf88,SMC2,UFM1,SARAF,HRASLS5,GABRA3,GABRG2,GDF9,TCERG1,ZNF638,CBX1,HTATSF1,RAB40B,WDFY3-AS2,PRUNE2,STON1,PCLO,CNTRL,GRB10,DIDO1,GUCY1B1,UBE2QL1,HMGCR,AGBL5,HNF4G,ICA1,ZNF181,IL6ST,KCNK3,KCNN2,CREG2,SYTL4,HECTD2,NCOA7,MARK3,AQP11,MATN3,MBNL1,LRP1B,MEST,KITLG,POC1B,MMP16,ZNF92,MYO6,ZC3H12B,NFYA,NINJ2,CNOT4,NUCB2,PCDH9,CCSER2,PURG,PDZRN4,LRP12,ING3,MINDY2,PPP1R1A,TATDN3,CCDC144B,PPP3CA,SLC26A11,RELN,VPS13C,SNRK,TMEM104,SPDL1,PTPRD,PTPRE,C1orf109,RASGRF1,RADX,FIGN,RGS4,SLC25A36,ELP2,NEK11,HUNK,NCBP3,ATXN2,ATXN7,SCP2,STUM,SCAF8,KIF21A,SEC31A,KANSL3,SEPHS1,ELMO2,SLC22A4,SNRPN,TMCC1,DOP1A,KDM4C,ZNF423,DDN,LMO3,ITPRID2,LARP4,CEP68,DIP2A,NSFL1C,VPS13A,PLCB1,SYN2,CAMTA1,FBXW11,SATB2,PCDHGB7,PCDHB4,PUM2,GPRIN3,TEK,FAM200B,DICER1,ZNF106,BHLHB9,KAT6B,RASD2,C9orf85,RGMB,ZNF346,SYNPO2,METTL3,TRPS1,DCBLD1,ANKRD20A2,FAM155A,USP1,CCDC14,TBC1D15,LGI4,PCDH20,ZNF24,TMEM237,EMSY,DNALI1,STOX2,KCNAB1,FIP1L1,FAM47E,HRASLS,ADAMTSL3,TTC7A,NETO1,AP3B2,SOCS4" MicroRNA hsa-miR-4251:mirSVR_highEffct hsa-miR-4251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.85E-73 3.27E-69 3.88E-72 3.57E-71 212 1356 "NCKAP5,NDRG3,INTS2,MTUS1,OSBPL1A,OSBPL6,BIN1,UPRT,BCAS1,USP37,SHROOM2,ARNTL,MARCH3,NUMB,DOCK11,ADGRB2,ARHGEF7,BTK,GYG2,CACNA1G,CA8,CACNB4,SLC25A14,RUNX1T1,DCLK1,ZMYM4,MAGI1,B4GALT6,TPP1,C4orf33,HECTD1,CNN3,ARMC8,COL9A1,IGDCC3,CPS1,GDA,CS,SEC24C,ARHGEF10,CSNK1G3,PDE4DIP,ZSCAN23,CCDC144A,GPRASP1,MAML1,DGKB,MYEF2,FBXL5,DMD,MAMLD1,E2F6,EDNRB,ANKRD46,HIPK3,PHF20L1,APH1A,EGR3,GOLGA7,STARD3NL,DCTN4,EPB41L2,ETV1,RRAGB,SCML2,FCGR1A,CEP78,FDFT1,FGF14,SEMA4D,ATP13A4,JKAMP,NBEA,SMC2,SPECC1,ZNF605,MSANTD4,FYB1,FYN,GALNT15,GABRB3,FAM120B,B4GALNT1,NEU3,ALDH1L1,MSTN,ARFIP1,GGTA1P,TCERG1,DBF4,TOX3,ZNF638,KDM2B,DIDO1,PRDM5,RABL2A,SHISA6,ZNF181,RBPJ,ITGAM,SLC35G1,KCNH2,KCNJ16,TTYH2,NCOA7,PACRG,CLEC18A,MARK1,MARK3,MAT2A,AQP11,MBD1,MEIS2,MIA2,NEK1,PCBP3,SLC11A2,IGSF11,P2RY1,GPR137C,GNG2,KCTD15,FAM216A,MAPKAP1,EXOSC10,DRAM2,PPP2R5E,MAPK9,PTK2,TMEM260,ZSCAN32,PTPRE,CEP97,ACSS3,RAD17,NWD1,RADX,RDX,ZFHX4,DCUN1D2,SETD5,CARF,ROBO2,RPE,SPIN3,ZC3H14,LRRK2,AP1AR,SCN8A,SCP2,FERMT1,SHC4,NLGN1,SEC31A,PPP4R3A,KBTBD4,SLC14A1,TET1,ZKSCAN3,ZNF667,RCOR3,ANKRD36,RBM34,KDM4B,DOP1A,BDP1,NMNAT2,SPP1,PEG10,RBM26,CLSTN2,SSTR2,LARP4,SYNE2,VPS13A,TAF6,MGRN1,SIN3B,DMXL2,ZFP90,ZEB1,TCF12,SYNE1,CCDC173,PMS2CL,MTMR14,ASXL3,TMPO,CDK20,NPL,C9orf85,SYNPO2,TRPS1,CA14,TUBB2A,CLHC1,SGK3,PLPPR2,MICU3,NDRG4,ZNF142,REEP1,SLC30A4,EMSY,PCBP4,WNK3,FZD3,HNRNPA3,RNF170,NETO2,FAM198A,SENP7" MicroRNA hsa-miR-1206:mirSVR_highEffct hsa-miR-1206:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.93E-73 3.32E-69 3.93E-72 3.62E-71 184 1027 "FMNL2,KLHL32,GALNT16,PWWP2A,NME5,TAOK1,SEMA6A,ALCAM,BBOX1,APC,TNRC6C,TMEFF1,ARNTL,NCOA1,SLC4A4,ATP2A2,TTLL9,CFLAR,DST,WASF1,CABP7,SLC25A14,CBR1,KRIT1,CCNH,USP6,DGKI,KCNAB3,ABI3BP,RCHY1,HAPLN1,CSNK1G3,SOCS5,PHACTR3,SLITRK5,PUM1,DOCK4,GPRASP1,KIAA0586,DGKB,AIF1L,ZBTB24,RAB39B,CPEB2,PDCD6IP,E2F5,PHC2,FCF1,FRY,PHF20L1,PLEKHA1,USPL1,TUBD1,EPB41,EPB41L2,SIRPB1,CLVS1,ABCA8,TMEM132C,SEC24B,OLFM1,PRKAG2,ATP13A4,C2orf88,POMT1,UFM1,PDLIM5,TPK1,CAMKK2,ZNF605,ST6GALNAC3,NSG1,CHL1,DISC1,GATM,SULT1C4,ARFIP1,PPARGC1A,HTATSF1,POLL,FUT10,STON1,CNTRL,GRIA2,DIDO1,FAM19A2,IRAK3,RASSF8,AGBL5,HNF4G,HNMT,ZDHHC15,TCEAL6,HSF2,IDH3A,IDH3B,JAK2,KCND2,KIF5A,LRP1B,KITLG,MITF,NOVA1,NTRK2,GPR137C,PCDH9,PDCD2,SLC10A4,ZDHHC8,NALCN,PIK3C2A,FAM216A,EPB41L4B,SH3KBP1,POLR2F,LRRN3,PPP2R5E,PPP3CA,GRAMD1C,CNTLN,ANKHD1,PTPN13,RASGRF2,GTDC1,FIGN,KLHL11,GSTCD,YY1AP1,TCP11L1,ABCA11P,ZNF568,AP1AR,ATXN2,ATXN7,SCP2,PEAR1,CHD9,BTBD3,NAPB,ATF7IP,CPEB4,ZNF667,UHRF1BP1L,CDK19,CLASP2,ZNF302,STAU1,SEPT8,DIP2A,VPS13A,PLCB1,COBL,C12orf76,ANKRD12,MTCL1,ADGRL3,TBCEL,ATMIN,SYNE1,SLC19A3,USP32P1,ARHGAP9,FRYL,ZFPM2,ZMAT3,MTMR14,C9orf85,STXBP4,PPIL6,TSC1,ZKSCAN5,FAM155A,VLDLR,TBC1D15,KCNT2,ZBTB38,FSTL5,FIP1L1,FAM47E,EPM2A,AMN1,FRMD6,ZNF30,FAM198A" MicroRNA hsa-miR-520b:mirSVR_highEffct hsa-miR-520b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.25E-73 3.50E-69 4.14E-72 3.81E-71 210 1332 "KIAA1211,PTCHD1,MTUS1,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,DOCK11,BACH1,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,SGCE,CA12,CALB2,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,AKAP7,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,HAPLN1,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,DCAF8,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,FYB1,MEGF11,IGSF5,TUBGCP4,ADAM28,GGTA1P,GHR,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPR12,GPR34,PCLO,FICD,ARHGAP36,SMAP1,MSL1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,OCRL,OGG1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,MAPKAP1,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,CEP97,ACSS3,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,FIGN,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,PCMTD2,CCDC102B,MCMBP,RPS20,SHC4,FBXO11,FNDC3A,WDR37,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,PLEKHH2,VLDLR,PCDH20,LYPD6,LAMP5,CADM2,LINC02210,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-555:mirSVR_lowEffct hsa-miR-555:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.27E-73 4.07E-69 4.81E-72 4.43E-71 195 1154 "ACADM,SYS1,GALNT13,RTL9,OSBPL8,CC2D2A,ABCD2,AMT,OGT,AQP6,TMEFF1,ARRB1,NUMB,CCAR2,TTLL9,BBS2,CAMK2G,CCNH,CBFA2T2,ZBED1,LARGE1,MAGI1,CDO1,SOCS6,CNOT8,TAOK2,ARHGAP22,FBXO7,ABCG2,FHL5,RTTN,BAG4,CLOCK,CREM,CSF1R,OSBPL3,CTH,DOCK4,KATNAL2,KCTD8,MAML1,DAPK1,DAPK3,SPOCK2,AIF1L,SPATA2,DCTN1,MYEF2,SNAP91,ZNF582-AS1,CASP8AP2,TSPAN5,HIPK3,CNNM1,HEYL,KLHL5,KMT5B,C8orf37,EPB41L2,DENND4A,MRPL37,MRPL10,MRVI1,FCGRT,FKTN,ZSCAN30,BAIAP2,SYNCRIP,IQCG,SEMA4D,EFCAB2,JKAMP,TVP23A,B4GALNT1,ZNF274,IP6K3,GATM,NEU3,ALDH1L1,LYVE1,ZNF276,RAB30,GPR75,ZNF638,MAP7D2,GPT2,WDFY3-AS2,FUT10,PCLO,BVES,LRRC75A,CELF5,SMAP1,MYLK2,KNDC1,SLC35G1,KCNN2,KCNN3,TTYH2,MBNL1,MEIS1,MN1,ZNF680,COL28A1,BLOC1S2,MXI1,ZNF862,NCAM2,NF1,NINJ2,NOVA1,NUCB2,PCDH9,PCSK1,PFKFB2,PFKFB4,PIK3C2A,SNX10,FAM216A,PSAT1,SEPT4,POLR2F,PPARA,PPP2R2C,DCHS2,MASP1,KLK6,QRICH1,PTPRD,ZSCAN2,ZNF615,NWD1,RASGRF1,ZDHHC14,KIF7,MRPS18A,KLHL11,SLC25A36,ZFHX4,CCDC82,CARF,RORB,PCMTD2,NEK11,LRRK2,TRAPPC13,ATXN2,HES6,SH3GL3,PPM1E,AMBRA1,ST6GAL1,NUBPL,PREX2,BTBD3,LIMS2,SLC6A8,CCDC88A,ATF7IP,USP33,BDP1,SPP1,SPART,CAMTA2,CEP68,ARC,SYP,CAMTA1,DNMBP,KIAA1107,ZEB1,RPGRIP1L,DOCK9,HIF3A,C18orf54,AP4E1,NACC2,ELP5,PPIL6,RUSC1,KCNE5,GORASP1,ZNF709,CCDC136,VSNL1,CLDND1,AGMO,NDRG4,ZFAND5,ADAMTS9,TMEM178A,KCNAB1,JMJD1C,TRAM2-AS1,ZDHHC20" MicroRNA hsa-miR-1324:mirSVR_highEffct hsa-miR-1324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.97E-73 4.46E-69 5.27E-72 4.85E-71 197 1178 "NCKAP5,PLEKHH1,KIAA1211,CC2D2A,SMIM17,ALCAM,ARHGAP20,AMPH,ZFAT,APAF1,MAGEE2,NT5C3B,FAM131A,PPP4R4,ZSCAN18,ATP1B3,DPY19L3,DST,ST3GAL5,SCAPER,CALB1,CALM1,RUNX1T1,CBR1,CERS5,L3MBTL4,MAGI1,MS4A7,TAOK2,COL11A2,SLC4A8,ZFP28,OSBPL3,UBXN2A,USP6NL,CCDC144A,GPRASP1,MYADM,PITPNC1,SNAP91,TMCC2,FAM107B,DNM1,USP3,DNAH9,CPEB2,FARSB,GOLT1B,EBF1,EDN1,PHC2,HIPK3,FCF1,FAM13A,EGFR,PLEKHA1,VPS13B,EPHB1,GPHN,ZNF549,SPEG,ST3GAL6,KAT8,SEC24B,FGF13,MAD2L2,FHL1,SUCO,ATP13A4,NOP56,SYT3,EFCAB2,TMEM107,SPECC1,KHDRBS3,CSPG5,SARAF,AP4B1,MEGF11,GAD1,MTHFD2,DISC1,GGT7,RUNDC3A,GLYR1,MSL3,ZNF638,FERMT2,CCDC184,STMN2,GRIA2,DIDO1,GRM8,FAM19A2,KAT7,ZBTB49,TOX2,HLF,HSF2,MSL1,IPO5,MAPT,MARK1,SHC3,NRBP2,CCDC13,NPY,IGSF11,OPRL1,CLDN11,ZNF827,PCDH8,ENPP2,PFKFB3,NALCN,PLCL1,PMP22,MAPKAP1,LRP12,MAGEL2,TATDN3,PPP3CA,PRKACB,EPDR1,HYDIN,CNNM2,GDPD2,TMEM260,PTPRE,QDPR,PID1,ZNF493,RDX,TRIM68,REV3L,MORC4,GTDC1,FIGN,SLC25A36,RNASEL,SETD5,CARF,ROBO2,SGSM1,KCNIP1,NCBP3,SARS,COPZ1,SGK1,KIF21A,WDR47,NAPB,CDK5RAP2,INTS9,SNRPN,SP4,ZNF423,SPART,ELOVL4,PLCB1,SYP,SYT1,COBL,MTCL1,PJA1,TBCEL,ZEB1,PCDHB7,TIAM1,METTL3,TRIO,ANKRD20A2,SSBP2,TTC3,UCHL1,CCDC14,XRCC4,ZNF711,ZNF24,NDRG4,CELF4,FSTL5,ZSCAN26,ANKS1B,FTSJ1,EMSY,STOX2,NAV3,KCNAB1,KAT6A,PHTF2,FBXO36,JMJD1C,NLRP3,RNF170,SNX14,GAN" MicroRNA hsa-miR-223:mirSVR_highEffct hsa-miR-223:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.95E-73 5.01E-69 5.90E-72 5.44E-71 179 974 "CLK4,XKR4,CCDC85A,AXIN2,PLEKHH1,DPY19L2P4,AK2,ALCAM,OGT,DPP10,LRCH2,LCORL,PKP4,APC,USP37,LGR5,LINC00173,MARCH3,CCDC74A,ZBTB10,SLC4A4,SLC2A11,SYNJ2,MTMR2,SGCE,IL33,ZNF555,PTBP2,PRC1,USP6,SCARB1,LRRFIP1,MAGI1,TIGD7,FBXO7,FAM19A5,LY86,AKAP6,LETMD1,RCHY1,RTTN,ZFP28,FAM171B,HAPLN1,RGS6,CSF2RA,LRIG1,LRRC3B,CSNK1E,SOCS5,SLITRK5,GREB1,CCDC144A,TCAF1,BRINP1,ARMCX2,SACS,SGSM2,CDON,DPH1,ABCC5,GOLT1B,RASGRP1,SEMA3D,YAF2,FAM13A,PHF20L1,EGFR,MBNL2,TENM1,PLEKHA1,ETV1,ARMCX1,CLVS1,TUBA1B,FCGR1A,FCGR1B,OLFM1,FHL1,POLK,ANKFY1,SLC37A3,CSPG5,KIAA1841,GHR,PPARGC1A,SPIN1,GPR34,PSIP1,ZHX1,ATXN2L,MIER3,HMGCL,CELF5,SMAP1,RBPJ,IL6ST,FAM69A,INPP5B,METTL21A,STXBP5,LAMA2,STMN1,LMO2,SYTL4,SMAD1,MAP4,LRP1B,MEIS1,XRRA1,MSR1,MX1,LAYN,NDP,NEFH,SLC11A2,NTRK2,OXTR,PAX6,GPR85,OLA1,ABCB1,PIK3C2A,PURG,SEPT4,RANBP3L,PRKCB,GRAMD1C,CNTLN,PTK2,TMEM255A,GTDC1,YY1AP1,CCDC102B,FBXW7,ABCA11P,RYR3,AP1AR,ATXN2,SCAF8,CNKSR2,ANKRD6,ABLIM3,FAM81A,SLC8A1,CDK5RAP2,SNCA,KDM3A,TSPYL2,POGZ,MESP1,KANK1,NSFL1C,SYT1,DOCK9,SLC19A3,SLC35G2,C18orf54,ERCC6L2,TMPO,ZKSCAN5,PLEKHH2,TBC1D15,P2RY12,CLDND1,PCDH20,LYPD6,REEP1,ANKS1B,SLC30A4,ZXDA,EMSY,PDSS2,FAM13C,KAT6A,NLRP3,NETO2,GAN,SENP7" MicroRNA hsa-miR-876-3p:mirSVR_lowEffct hsa-miR-876-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-72 5.65E-69 6.65E-72 6.12E-71 200 1215 "KLHL32,GALNT16,AP2A2,TBC1D14,SORCS2,SPOP,ARHGAP20,ALK,GPRASP2,AMPD2,OGT,DPP10,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK10,ATP2A2,ADGRB2,BCL7A,KSR1,WASF1,KALRN,CAMK2A,VXN,LDB2,C1orf52,SEPT7,SRSF11,SOCS6,B4GALT6,LHX2,EPS15L1,IGLON5,CNTN1,PCYT1B,CREM,RBM39,RGS6,CSNK1E,OSBPL3,CST3,RASGEF1C,ERC2,ARHGEF4,CCDC144A,ZNF337,RASSF2,KIAA0586,DGKB,DGKG,ARMCX4,YTHDC1,DGCR5,ZBTB24,USP3,CPEB2,CNNM1,TENM1,TNK2,EPB41L2,ZNF549,SPEG,RASL12,F5,TAOK3,ZNF589,POLR1B,EVL,FLT1,COQ5,TMEM107,SMC2,PDLIM5,ATP2C1,CELF1,ST6GALNAC3,DOT1L,HRASLS5,GAD1,RAPGEF6,DISC1,IGSF5,GCNT2,PPARGC1A,TOX3,KDM2B,POLL,LOXL3,GPD1,ATP2B1-AS1,SPACA9,RNF165,GUCY1A1,FAM222A,ELOVL5,DHX35,EID2B,IFI16,GAREM2,ZIC5,INPP5B,STXBP5,TTYH2,PAXBP1,LMO2,HECTD2,MARK1,MBNL1,CHST6,TM6SF1,BLOC1S2,ADAM22,LAYN,MYO9A,NCAM2,NFE2L2,OCRL,DPY19L2P2,GPR173,PRIMPOL,ANKRD16,SCHIP1,EPB41L4B,MINDY2,LRRN3,PPP3CA,SLC26A11,HYDIN,PTK2,TUG1,SLC25A48,FAT4,NWD1,RAP1GDS1,KHDRBS2,ERI2,GTDC1,MRPS18A,RIC8B,CCDC82,ZNF532,ALG9,MRAP2,NEK11,RTN1,SH3BGR,KIF16B,AMBRA1,CCDC92,ANKRD6,WDR37,FAM214B,SLC8A1,SMARCA4,RCOR3,MBD5,DOP1A,ZSWIM8,SP4,MYCBP2,NKAIN2,PHLDB1,SEPT3,TACC1,MTCL1,CUX2,TPCN2,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,TMEM9,HEY1,TK2,RIMBP2,KAT6B,RGMB,SYNPO2,SSBP2,ZNF709,CLDND1,SLC47A2,ZBTB38,EMSY,CADM2,SLC38A1,FIP1L1,WNK2,FZD3,ST7,HNRNPA3,CASC15,NETO1,CPNE4,FAM198A" MicroRNA hsa-miR-668:mirSVR_lowEffct hsa-miR-668:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-72 6.40E-69 7.52E-72 6.93E-71 208 1312 "ABHD6,ADORA2A,PTCHD1,ADRB2,ARHGAP20,ALK,AMT,PHF12,UPRT,TNRC6C,ARHGDIG,DNAH17,INSYN2B,N4BP2L1,BACH1,RGS9,MTMR3,CFAP410,CACNA1A,THSD7A,CAMK2G,CH25H,PRC1,CBS,ENTPD6,AP4M1,LARGE1,B4GALT6,NDST3,FAM189A2,MAP4K4,COL4A5,SUMF2,SEC31B,HAPLN1,RGS6,RIMS4,GREB1,RUBCN,TCAF1,ZFYVE16,LONRF1,TMEM170A,ARMCX2,TMEM130,LYPD1,WDR20,KIF19,ZNF582-AS1,RAB39B,DOCK2,CASP8AP2,PDCD6IP,E2F5,EBF1,CNNM1,HEYL,FSD1L,PHF20L1,GOLGA7,KCTD3,EPB41,SRRM1,ZNF549,ARMCX1,CHST15,FKTN,STRADA,FER,FGF13,PRKAG2,SLC37A3,C2orf88,EFCAB2,NBEA,ATP2C1,MPP6,DISC1,GCNT2,GDF9,GGT7,MALT1,ZNF276,ZNF638,KIAA1958,MAP7D2,DCLK2,GRM2,GUCY1B1,MUM1,RASSF8,PACSIN2,MIER3,USP51,FAM95B1,SCIN,INPP5B,INSM1,SLC35G1,KCNJ5,KCNN2,KCNN3,STXBP5,LIFR,SYTL4,HECTD2,MAPT,AQP11,MBP,KITLG,MITF,AFDN,GIT1,SAMD5,RTL5,NELL2,NOVA2,DNHD1,NPTX2,OXTR,P2RX7,PCSK1,GPR85,ZNF655,FAM216A,PDZRN4,MAPKAP1,LRP12,PRKAB2,PRKCB,PRPSAP2,RELN,DEF8,SNRK,QRICH1,CNTLN,PTPRH,ZNF793,NWD1,OXR1,RASGRF2,RADX,RDX,TRIM68,GTDC1,RFX3,RGS3,CCDC25,NEK11,FBXW7,MEG3,FNDC3A,BTBD3,ARHGEF40,ARFGAP1,ANKRD36,KIF13A,SNRPN,FAM126B,USP33,DOP1A,PDZD2,SP2,PEG10,ZBTB43,TSPYL2,PBLD,KANK1,VPS13A,ARC,SYP,CAMTA1,ALG1,KIAA0930,CUX2,TPCN2,CLASP1,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,FAM200B,GALNT17,R3HDM1,TPM2,METTL3,DCBLD1,RPRM,UBE2H,SLC35A4,UGT8,WIPF1,GUSBP1,ZNF28,ATP6V0E2,ZBTB38,TMEM237,STOX2,ADAMTS9,SIGLEC10,FIP1L1,DNAH10,ZDHHC20" MicroRNA hsa-miR-4265:mirSVR_lowEffct hsa-miR-4265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-72 6.43E-69 7.55E-72 6.95E-71 217 1423 "RALGAPA1,EMILIN3,FMNL2,GALNT16,ADORA1,KCTD16,WDR35,PCDH10,LRFN1,ZFAT,FAM131A,SEMA4G,MADD,DYNLL1,ADGRB2,BTK,IL33,KALRN,RHBDL1,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,NRXN3,CLTC,QKI,CNTFR,IQCK,SMARCAL1,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,ARHGEF10,CST3,ARHGEF4,BOC,MYADM,ZNF337,IP6K1,DGCR5,HEPH,TIAM2,FBXL5,KIAA0753,CD99L2,ARRDC4,TOM1,EDN1,EDNRB,YAF2,PHF20L1,APH1A,EGFR,GOLGA7,IRAK4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,FLT1,NOP56,CINP,NEURL4,HRASLS5,B4GALNT1,SEPT9,ALDH1L1,TUBGCP4,TTBK1,ZNF638,MAP7D2,POLL,PRUNE2,STON1,MCHR1,RNF165,ADAMTS6,HMGCL,HNF4G,DHX35,CELF5,MYLK2,LRRC25,INSM1,C2CD4C,SLC35G1,KCNH2,LIFR,SFXN5,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,MYO5A,MYO7A,CLDN11,OXTR,P2RY1,CDK18,FAM218A,CCSER2,PLCB2,MAPKAP1,LRP12,FA2H,POLR2F,PPARA,PRODH,MASP1,RELN,SAMD9,WDR25,ZSCAN2,NWD1,RASGRF1,GTDC1,CARF,KIRREL1,ROBO2,CCDC25,SNX22,SGSM1,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,ATAT1,KCNIP3,RYR3,LRFN5,SCP2,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,FERMT1,SHMT2,WDR37,LIMS2,KANSL3,PKNOX2,SLC6A8,LGI3,KIF13A,SNRPN,FAM219A,TSNAXIP1,SOX15,IQSEC2,CLSTN2,ZC4H2,SSPO,SEPT3,JMJD6,ARC,COBL,TACC1,MTCL1,MLST8,IQCE,TPCN2,CLASP1,SZT2,SYNE1,CYB561A3,GALNT17,TMEM9,ERCC6L2,RIMBP2,CABIN1,WBP2,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,RICTOR,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,NDRG4,ZBTB38,AMZ1,DPYSL5,PCBP1-AS1,DNALI1,RGS7BP,TMEM63C,RNF170,JPH3" MicroRNA hsa-miR-1283:PITA hsa-miR-1283:PITA_TOP PITA 1.32E-72 7.37E-69 8.65E-72 7.97E-71 146 638 "RALGAPA1,ADD1,PWWP2A,INTS2,MTUS1,HECW2,PCDH19,OSBPL8,SRPX,UNC79,LRCH2,SEMA4G,SLC4A4,JAZF1,CALM1,CH25H,LRBA,CDH2,ZMYM4,CHN1,NRXN3,FAM19A5,QKI,AHCTF1,SLC35F1,CRHBP,SIPA1L1,SOCS5,CNTNAP2,PLCXD3,PUM1,KIAA0408,HDAC4,MATR3,MAML1,DAPK1,SNAP91,DYNC1I1,CDON,CPEB2,GOLT1B,EDNRA,PHC2,FRY,APH1A,MBNL2,EGR3,EIF4G2,COPS4,RGS17,UBE2E3,MEX3B,FOXO3,ANKFY1,NBEA,FUT9,OGA,MEGF10,GABRB3,PPARGC1A,RNPS1,SPIN1,TNRC6A,GLUL,GNAO1,STON1,GPR37,ZBTB49,PSIP1,MIER3,HMGCR,AGBL5,NEGR1,IGF1,ZIC5,SLC6A17,STXBP5,LIFR,CHIC1,LRP1B,MEF2C,HS6ST3,MYO5A,NEXMIF,HNRNPM,PDE4D,MAPKAP1,MINDY2,PPP2R5E,PPP3CA,DIRAS2,PRPSAP2,PTCH1,ELOVL2,PTK2,PTN,PTPRB,USP47,OXR1,RDX,RFX3,UBR7,NUDT11,ZFHX4,RORB,ARMH4,FBXW7,NCBP3,SATB1,ATXN2,CASC3,PPM1E,BTBD3,WDR47,SEPHS1,CCDC88A,CPEB4,SNAP25,PDZRN3,MYO16,SOX11,SP4,PEG10,SYT1,TAL1,TCF4,DMXL2,SZT2,SIRT1,AKTIP,SLC44A1,ERCC6L2,KAT6B,TPM1,TRPS1,UBE3A,UBTF,TBC1D15,CELF4,NAV3,FZD3,HNRNPA3,JMJD1C,MSRB3,SOCS4,SENP7" MicroRNA hsa-miR-491-3p:mirSVR_highEffct hsa-miR-491-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-72 7.39E-69 8.66E-72 7.98E-71 199 1205 "FMNL2,CCDC85A,ADD2,PWWP2A,PTCHD1,HECW2,OSBPL1A,WDR35,C1QTNF3,SMIM17,SEMA6A,ALCAM,PCDH10,FAM135A,PARG,APBA2,LGR5,LINC00173,NCOA1,NUMB,ZNF599,BMP7,DST,ARHGEF7,BTK,SCAPER,MTMR2,CABP7,THSD7A,CALM1,KALRN,NFS1,CBR1,CBFA2T2,LRBA,ZMYM4,SRSF11,RAB33A,ARHGEF6,SH2B1,SEC24C,SOCS5,ERC2,APPL1,PHF14,CYBB,DOCK4,ARHGAP24,DGKB,SPOCK2,PABPC5,MYEF2,ALKBH8,RHOBTB1,PLPPR4,SNAP91,DMD,USP3,DYNC1I1,CPEB2,PDCD6IP,ECM2,GOLT1B,SEMA3D,PHF20L1,EGFR,KMT5B,ASB3,EIF4G2,PLEKHA1,NRN1,ARMCX1,PTK2B,ZNF589,SLC9B2,POLR1B,FOXO3,FLT1,ANKFY1,STAMBP,ATP6V1H,ST6GALNAC3,AP4B1,GABRB3,ADAM28,GHR,PPARGC1A,COPS8,HPGDS,LUZP2,PRDM5,FAM19A2,FAM107A,MAP4K5,HNMT,ZDHHC15,IDH3A,LRRCC1,SCIN,HECTD2,NCOA7,MARK1,LYPLAL1,AQP11,MATN2,MEST,KCTD6,AFDN,NF1,NOVA1,CLDN11,PCDH9,PRTG,ABCB1,XRN1,PLIN1,STRN3,LRP12,KANSL1,HYDIN,SAMD9,MTMR10,TMEM260,PTX3,PEX2,TMEM255A,FAM184A,ZDHHC14,RDX,RGS3,ZFHX4,ZNF532,GSTCD,PCMTD2,RPL15,FBXW7,TCP11L1,LRRK2,CLIP1,RTN1,ZNF568,FNIP1,FNDC3A,FHOD3,CNKSR2,SYBU,SEC31A,SLA,FAM81A,PPP4R3A,EPN2,CPEB4,ANKRD36,SNRPN,HECW1,UHRF1BP1L,CDK19,RBM26,TROVE2,LARP4,ERBIN,ZSCAN29,ELOVL4,SEPT8,RGL1,NSFL1C,NECAB1,JMJD6,PRRC2C,PLCB1,TACC1,MTCL1,ZFP90,PCDHB7,PCDHB6,PUM2,USP32P1,SIK3,TEK,FAM200B,SIRT1,SLC44A1,HEY1,ERCC6L2,BEX4,RIMBP2,TRIO,TUBB1,SLC35A4,PLEKHH2,USP1,ZNF138,ZNF154,FSTL5,FAM47E,PLSCR4,ADAMTSL3,MSRB3,KLHDC1" MicroRNA hsa-miR-875-5p:mirSVR_lowEffct hsa-miR-875-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-72 7.77E-69 9.10E-72 8.38E-71 203 1253 "ACTN1,FMNL2,KLHL32,ADCY6,PWWP2A,MTUS1,CASKIN1,KCTD16,HACE1,OSBPL6,OSBPL8,OGT,CCDC146,PKP4,APC,NCOA1,SEC11C,BCHE,BMP7,ARHGEF7,CFAP410,CACNB4,KALRN,ZNF501,USP6,P2RX6,LRRFIP1,MAGI1,NDST3,CLCN3,MYL6B,QKI,CNR1,PCYT1B,ARMC8,ANKRD35,COL9A1,MYRIP,ZNF521,ZFP28,CLOCK,PREPL,HAPLN1,ANKRD44,VCAN,PDE4DIP,SLITRK5,CTH,GPRASP1,HDAC4,KIAA0586,DGKG,TMEM170A,BRINP1,AIF1L,DNAL1,TIAM2,MFAP3L,ZC3H11A,SV2B,DMD,NR1D2,CPEB2,DOCK2,DPYSL2,PDCD6IP,EDN3,APH1A,GOLGA7,PCOLCE2,COQ7,RABEPK,CEP85L,ETV1,CLVS1,NSRP1,DLC1,ZSCAN30,FER,FGF12,MEX3B,SEC23B,PCYOX1,ZNF605,ST6GALNAC3,STAU2,GABRG2,ERAP1,SIGLEC8,GATM,MALT1,TCERG1,LUZP2,LOXL3,GRB10,LINC01089,SOX21,FRMD5,PACSIN2,ATXN2L,MIER3,ZDHHC15,IDH3A,C2orf72,IL6ST,INPP5B,SLC35G1,ASPRV1,SMAD9,CHIC1,MEST,AFDN,MMP16,MSR1,NEK1,OCRL,GLIPR1L2,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDE3A,NALCN,FAM218A,PLCB2,MTRF1L,MAPKAP1,LRP12,ING3,EPB41L4B,MINDY2,PPP1R1A,PPP2R5E,RASGEF1B,CEP41,DIRAS2,DCHS2,ZIK1,ZNF493,RET,GTDC1,PBRM1,RNASEL,ZFHX4,DCUN1D2,TMLHE,CARF,ZNF568,TRAPPC13,SEMA6D,PEAR1,SH3BGR,SH3GL3,KIF16B,HKDC1,DHX30,ATF7IP,TET1,ZNF667,SNRPN,BDP1,TEX2,PEG10,DDN,ZSCAN29,KANK1,ZC3H4,FAM208A,KIAA1107,TCF4,TCF12,OBSL1,RIMBP2,NPL,PDSS1,STXBP4,TTC3,PRR18,CLHC1,FAM155A,OSBP2,FLRT2,ZNF709,PLPPR2,RICTOR,TRIM9,ZNF142,ANKS1B,SPIRE1,MFF,CADM2,STOX2,HPS4,URM1,FAM47E,PDSS2,EPM2A,FAM13C,MRPL47,JMJD1C,RNF170,NETO2,GAN" MicroRNA hsa-miR-367-3p:TargetScan hsa-miR-367-3p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-32-5p:TargetScan hsa-miR-32-5p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-25-3p:TargetScan hsa-miR-25-3p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-92a-3p:TargetScan hsa-miR-92a-3p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-363-3p:TargetScan hsa-miR-363-3p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-92b-3p:TargetScan hsa-miR-92b-3p TargetScan 1.57E-72 8.81E-69 1.02E-71 9.43E-71 160 776 "NCKAP5,ELFN2,RNF157,PWWP2A,KIAA1211,RNF150,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,CASK,MARCH3,NCOA1,INSYN2B,ATP2A2,ADAM23,BACH1,HCN2,BMP7,FUBP1,CACNA1I,LDLRAD4,CACNA2D1,KALRN,CAMK2A,RUNX1T1,DLGAP2,CLGN,CFL2,FOXN3,QKI,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,PITPNC1,KLHL3,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,DNAJC27,POLK,NSG1,GAA,GABRA3,IQGAP2,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,DCLK2,PRRC2B,GRM2,KAT7,HAS2,MIER3,NEGR1,RBPJ,C2CD4C,KCND2,KCNK3,KCNN3,KPNA5,IPO5,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,GPR173,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,DCHS2,PTPRD,PTPRG,RAD51D,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN7,SCN8A,FNIP1,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,FAM126B,PDZD2,DOK5,HECW1,MYCBP2,ELOVL4,RGL1,ATMIN,SATB2,DOCK9,FRYL,NACC2,CSMD1,PCDH20,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-15a*:mirSVR_lowEffct hsa-miR-15a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-72 9.20E-69 1.07E-71 9.83E-71 213 1376 "RALGAPA1,EMILIN3,PWWP2A,LRFN2,KLHL13,KCTD16,KIAA1324,SMIM17,ARHGAP20,PI16,CCDC146,MAP4K3,PKP4,UPRT,USP37,PLA2G4C,PCDHGB4,SLC2A11,LINC00847,CFLAR,SYNJ1,SYNJ2,ARHGEF7,IL33,CAMK2G,CAST,KRIT1,LRBA,LRRFIP1,MAGI1,MS4A7,EPS15L1,NRXN3,PPT2,CLCN3,CLTC,VAX2,CNTN1,ARMC8,ANKRD35,AHCTF1,SMARCAL1,ZNF521,FAM171B,C2CD2,CREM,GDA,MROH8,ERC2,BOC,DCAF8,ZNF337,DGKG,ARMCX4,DNM1,DNAH9,DPP6,KLHL5,EIF4G2,EMX2,RCAN2,ZNF549,MRVI1,F5,TUBB3,FER,MED12L,GTF2IRD2,TMEM164,C2orf88,STAU2,MSANTD4,SARAF,HRASLS5,GABRA3,RAPGEF6,ZNF274,SIGLEC8,SEPT9,IGSF5,RUNDC3A,TXNL4A,TNRC6A,LUZP2,DCLK2,GRIA2,CIT,HLF,VSIG4,GABARAPL2,ZDHHC15,HSF2,MSL1,IDH3A,IFI16,ZNF546,LRRC25,IL6ST,INPP5B,ITPKB,SLC35G1,LAMP2,LIMS1,GPR155,MAP2,MAP4,MBD1,CHIC1,MEIS1,DBNL,BLOC1S2,MSR1,MXI1,P2RY13,NF1,NFE2L2,NTRK2,OGG1,GPR137C,PCDHGC3,PDE4D,GNG2,PFKFB4,PIK3R1,CCSER2,JAKMIP1,SCHIP1,PPM1B,RELN,SAMD9,LAMA1,QRICH1,ZSCAN32,PTPRG,TMEM255A,ACSS3,RAD51D,RASGRF1,ZDHHC14,GTDC1,ZFHX4,ARMC5,ROBO1,RORB,ELP2,RPL15,STK32B,KCNIP1,CCDC112,FAM192A,RMI1,MRAS,ASAP3,CPEB3,SHC4,FNDC3A,BTBD3,PKNOX2,SLC6A11,SEPHS1,SLC12A2,SLC22A4,GKAP1,SMARCC2,SNCA,DOP1A,SPATA7,ZBTB43,SPART,NFASC,ZC4H2,RGL1,KANK1,PRRC2C,NUDT10,ASTN2,FBXW11,SIN3B,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ZNF106,CSMD1,CDK20,TPM2,ZNF346,TRIO,UGT8,OSBP2,ZNF24,TRIM9,ZBTB38,REEP1,PCBP1-AS1,ZFAND5,ADAMTS9,VPS35L,GAL3ST3,PPP1R3F,KCNAB1,FIP1L1,FBXO36,SOCS4" MicroRNA hsa-miR-503:mirSVR_lowEffct hsa-miR-503:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-72 9.42E-69 1.09E-71 1.01E-70 175 934 "RALGAPA1,NCKAP5,TMEM132B,GALNT13,RNF150,ADRB2,AP2A1,C1QTNF1,USP35,SRPX,FAM135A,OGT,SUGT1P4-STRA6LP-CCDC180,APC,TNRC6C,PPFIA3,IGDCC4,STK33,NUMB,INSYN2B,ADAM23,TTLL9,BMPR1B,FUBP1,NAE1,JAZF1,CACNA1I,KALRN,CAST,RUNX1T1,USP2,MAGI1,NDST3,NRXN3,CLTC,HECTD1,TBPL1,AHCTF1,CSF2RA,SNPH,ARHGAP24,INTS1,ARMCX2,TMCC2,EXOG,HS3ST2,NYAP1,USP3,DYNC1I1,CDON,DMTF1,DNM1L,ANKRD46,FRY,PHF20L1,SUGP2,EIF4G1,PLEKHA1,ING4,ENO2,CEP85L,ARMCX1,TAOK3,FER,BAIAP2,PRKAG2,MEX3B,IP6K2,RGPD5,SEMA4D,WDR83,HHIPL1,DOT1L,GABRB3,ERAP1,USP19,RUNDC3A,BRD8,RAB30,TOX3,TNRC6A,GNAL,FERMT2,STMN2,GRM2,VSIG4,SYNPO,NKD1,NIM1K,C2CD4C,SLC35G1,KIF2A,KIF5A,L1CAM,LIMS1,PACRG,MAN2A2,AQP11,TM6SF1,LRP1B,MOV10,NF1,NUCB2,DPY19L2P2,PDE1B,GNG2,KCTD15,JAKMIP1,PURG,PMP22,SCHIP1,RASGEF1B,MAPK3,SLC26A11,RELN,KLK6,CNNM2,WBP1L,MTMR10,PTPRD,PTPRN,TMEM255A,FAT4,RET,ZFHX4,GSTCD,FBXW7,KIAA0895L,SALL1,ATXN2,SCN8A,PRCD,SCAF8,SGK1,FRMPD1,KIF16B,CPEB3,CHD9,DZIP1,WDR37,FAM81A,SLC2A5,BTBD3,IFT122,MBD5,MYO16,SOX3,LHPP,PBLD,CAMTA2,MPRIP,ADHFE1,KANK1,STXBP1,SYPL1,C12orf76,MTCL1,CAMTA1,AGTPBP1,MGRN1,SYNE1,PCDHA5,NR2E1,TPM2,ELP5,BCL2L13,ZFP41,STOX2,SEMA3B,PLSCR4,RTN4,CASC15,MSRB3,FXR1,JPH3" MicroRNA hsa-miR-1225-5p:mirSVR_lowEffct hsa-miR-1225-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-72 9.72E-69 1.13E-71 1.04E-70 180 989 "SYN3,NCKAP5,DOC2A,SEMA7A,MYH7B,SUGT1P4-STRA6LP-CCDC180,BCAS1,PCDHGB4,DPY19L3,ADAM15,ADGRB3,CFLAR,JAZF1,KALRN,CERS5,ENTPD2,LOC730101,LARGE1,CHGB,CHN2,PLEKHB1,CLTB,FAM149A,LETMD1,MYRIP,IGDCC3,SEC31B,CDC42BPB,AKAP12,UBXN2A,PHF14,CTH,GREB1,PUM1,KATNAL2,DGKB,BRINP1,GSDME,SEC16A,GRIN3A,SLC29A4,CDON,DPP6,PDCD6IP,DTNA,DNAJB6,CNNM1,YAF2,MBNL2,ELN,C8orf37,DCTN4,EPB41L2,STX2,DNAJC27,SCML2,CHST15,KAT8,PPP1R1B,ZNF589,FGF13,IQCG,FLT1,ANKFY1,EFCAB2,CELF1,ZMAT1,GABRB3,IP6K3,KIAA1841,RAB30,MAP7D2,GNAO1,WDFY3-AS2,SPACA9,RABL2A,RNFT2,MUM1,PADI2,NCKAP1L,AGBL5,ZDHHC15,SMAP1,IDH3A,SOWAHA,SCIN,KCND2,KCNN3,KIT,L1CAM,STMN1,LIMS1,HECTD2,MBNL1,ZNF680,NEXMIF,NCF2,DNHD1,PCDHGC3,CDK18,PFKFB2,NALCN,SNX10,SLC25A23,PLXNB1,SEPT4,SH3KBP1,PPP1R1A,PPP2R2C,RASGEF1B,DIRAS2,PTPRN,TUG1,PID1,CEP97,ZNF793,KIF7,SETD5,YY1AP1,ATP8B4,RPS6KA2,LRRK2,ATAT1,FOXRED1,MYO18A,CHD9,ST6GAL1,KANSL3,CCDC88A,ELMO2,ANKRD36,MBD5,SNRPN,PDZRN3,DOP1A,ZHX3,SPP1,KDM4C,PEG10,ZC3H13,NFASC,STAC2,VPS13A,PLCB1,ANKRD12,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,FAM189A1,TK2,NR2E1,TMPO,BEX4,PIK3R5,CDK20,ZNF346,TRIO,TRPS1,PPIL6,USP1,VLDLR,TBC1D15,LYPD6,SMARCAD1,DHX33,HPS4,PPP1R3F,WNK2,PARP11,RGS7BP,SOCS4" MicroRNA hsa-miR-10b*:mirSVR_highEffct hsa-miR-10b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.61E-72 1.46E-68 1.69E-71 1.56E-70 189 1093 "KDM5D,KLHL32,INTS2,HFM1,ARHGAP20,PCDH10,LCORL,PHF12,PHYHD1,DYNLL1,BACH1,ADGRB2,SCAPER,CACNA1G,VXN,CH25H,KRIT1,MTMR7,SLC16A4,C1orf52,LOC730101,CDO1,CFL2,CNOT8,NRXN3,CNGA3,CNR1,AKAP6,CRHBP,SNCAIP,SLITRK5,PUM1,TIAM2,RHOBTB1,PLPPR4,RAB39B,DNM1,HS3ST2,ABCC5,DNM1L,PHC2,ANKRD46,HIPK3,YAF2,FAM13A,PHF20L1,EGFR,MBNL2,KMT5B,ASB3,TMEM35A,VPS13B,EPHB1,DENND4A,EXTL2,ZNF585B,FCGRT,ZSCAN30,GORAB,SEC24B,FER,FGF13,SUCO,SYNCRIP,RGPD5,NOP56,SMC2,BRSK1,ZMAT1,GABRG2,FAM120B,DISC1,TUBGCP4,ARFIP1,COPS8,DBF4,GLI2,RAB30,ZNF638,ADGRA3,GPR12,ATP2B1-AS1,GRIA2,PSIP1,VSIG4,CFAP126,SOWAHA,RBPJ,IL6ST,ZNF678,LRRTM1,KLHL23,HECTD2,MEIS1,MEST,MIA2,AFDN,BLOC1S2,MSR1,DNHD1,NTRK3,OPRL1,CLDN11,CNTN3,PDPK1,PFKFB2,NLGN3,CCSER2,RETREG1,MINDY2,TATDN3,CCDC144B,PPP3CC,GRAMD1C,HYDIN,MASP1,CNNM2,CNTLN,TMEM260,ZSCAN32,PEX2,ACSS3,GTDC1,UBR7,TMLHE,CARF,NEK11,ATP8B4,ABCA11P,KCNIP1,TRAPPC13,SALL1,SEMA6D,LRFN5,FBXO11,R3HDM2,NUBPL,WDR37,SLA,SLC12A2,ELMO2,ANKRD36,KIF13A,SNRPN,TMCC1,DOK5,NMNAT2,LMO3,POGZ,DIP2A,NECAB1,VPS13A,PLCB1,SYT1,ANKRD12,FBXW11,WSCD1,SATB2,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,AKTIP,ACTR6,ASXL3,TNS1,METTL3,PDSS1,RUNDC3B,ANKRD20A2,CLHC1,RPL7L1,PLEKHH2,VLDLR,RICTOR,ZIC2,FSTL5,UPF3A,VPS35L,WNK3,RGS7BP,AMN1,JMJD1C,TRAM2-AS1" MicroRNA hsa-miR-3130-3p:mirSVR_lowEffct hsa-miR-3130-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-72 1.46E-68 1.69E-71 1.56E-70 230 1595 "ACADM,NCKAP5,TMEM132B,GALNT16,ADRA1D,BEND6,INTS2,PCDH10,AMPD2,CDC42BPA,DPP10,PHF12,USP37,SPTBN4,SLC4A4,ATP2A2,ADAM23,KSR1,BMP7,DST,SYNJ2,HAP1,PTBP2,SLC25A14,HIP1R,ENTPD6,LRBA,SEPT7,CDH2,ZMYM4,NOG,COPB2,CHN2,MAP4K4,FAM149A,SUMF2,SEC31B,C2CD2,SH2B1,NCOR1,GDA,ABCG1,SNCAIP,CSF1,SEC24C,VCAN,RASGEF1C,DZIP3,KIAA0040,RUBCN,USP6NL,EARS2,TBC1D5,LIN54,DGKG,GIT2,TIAM2,MFAP3L,POM121,KIF19,ECM2,ABCC5,EDNRB,HIPK3,FCF1,YAF2,CELSR3,TENM1,ENPP6,SPEG,MRPL37,APC2,FKTN,MED12L,GTF2IRD2,FGF1,FGFR1,SYNCRIP,PSD2,STAMBP,ATP6V1H,NSG1,STAU2,ZNF44,ERAP1,DISC1,SULT1C4,GGTA1P,GGT5,DBF4,FERMT2,LILRB4,TMEM121B,ADAMTS13,CIT,ADAMTS6,MIER3,ZNF491,NME9,C2CD4C,SLC35G1,CDH20,KCNK3,KIT,MAN2A2,MARK1,MATN2,PPM1L,MN1,GIT1,COL28A1,MXI1,MYCN,MYO5A,NEFM,NFYA,NNAT,CNOT4,NTRK2,OCRL,PCDH8,CDK18,PDPK1,PIK3R1,CCSER2,SCHIP1,RETREG2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CC,RANBP3L,RASGEF1B,PRKACB,CEP41,HYDIN,PIGG,CNTLN,PTPRG,C1orf109,NKAIN1,SLC25A48,ACSS3,IQSEC3,ZDHHC14,RET,ERI2,PBRM1,ZFHX4,ARMC5,RPE,SNX22,KIAA0895L,MCMBP,ADAL,STK32B,CSRNP3,ATXN2,SCN2B,SCP2,PPM1E,FERMT1,CPEB3,HKDC1,BTBD3,KANSL3,SLC6A8,SEPHS1,ARHGEF40,BTBD7,TET1,CDK5RAP2,MAPKBP1,SNRPN,TMCC1,FNBP1,ZSWIM8,SP4,NMNAT2,KDM4C,PEG10,PHLDB1,ZC3H4,DNAJC9,SYP,MLST8,CLASP1,NAT16,DOCK9,PHF24,SLC19A3,OBSL1,FRYL,SIK3,SIRT1,ITGB3BP,ARL10,TIAM1,NR2E1,RIMBP2,RASD2,TPM1,TPM2,C9orf85,CHST5,ELP5,PDSS1,TRO,HIRA,PLEKHH2,ZNF709,MTCH1,LMF1,LGI4,ZNF711,MKRN3,LYPD6,DPYSL5,ZXDA,SLC38A1,RNF103,HPS4,PDSS2,ST7,SMIM8,FBXO36,ADAMTSL3,ZDHHC20,FRMD6,SENP7" MicroRNA hsa-miR-4327:mirSVR_lowEffct hsa-miR-4327:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.67E-72 1.50E-68 1.73E-71 1.59E-70 198 1198 "FMNL2,ADD2,PLEKHH1,USP31,RNF150,BEND6,KIAA1324,TXNDC16,PCDH10,LCORL,MAP4K3,LGR5,NUMB,SLC4A4,NAE1,CACNA1G,IL33,KALRN,HAP1,MTMR7,P2RX6,SYNGR3,SEPT7,ZBED1,LOC730101,NUMBL,STOML1,MAGED1,MROH8,VCAN,SOCS5,VAC14-AS1,FAM169A,SLITRK5,KIAA0040,RIMS2,MYADM,ARHGAP24,MATR3,DGKB,SPATA2,DCTN1,ELMO1,ZC3H11A,EXOG,DMD,DPYSL2,DTNB,EDN1,EDNRA,EDNRB,HIPK3,HEYL,RASGRP1,TMTC1,PHF20L1,KMT5B,AASS,KCTD3,PAN3,USPL1,VPS13B,DENND4A,NCALD,DNAJC27,GMPR2,TBC1D16,DLC1,CHST15,FER,FHL1,UBE2E3,MEX3B,RGPD5,NOP56,ZNF605,STAU2,MSANTD4,GAD1,GALC,DISC1,INPP5K,TUBGCP4,SULT1C4,TCERG1,COPS8,TOX3,HTATSF1,DCLK2,ADGRA3,ATP2B1-AS1,GRIA2,PRDM5,LINC01089,FAM19A2,RNF165,AP4S1,ATOH8,PADI2,TNFAIP8L3,SMAP1,FAM95B1,RBPJ,IL12A,INPP5B,KCNB1,KHK,CREG2,AQP11,CHIC1,SCAMP5,POC1B,MMP16,ADAM22,NCAM2,NEFM,NELL2,NFYA,SMIM11A,IGSF11,OGG1,ZNF827,PCDH9,PFKFB3,NALCN,GPSM2,NLE1,PCDH18,PDZRN4,POU6F1,PPP2R2C,KANSL1,PRKAB2,CNNM2,ELOVL2,PTPRE,CEP97,ZNF793,RASGRF2,KHDRBS2,GTDC1,RGS12,SLC25A36,KLHDC8A,ARMC5,FBXW7,KCNIP3,RYR3,ATXN7,KIF21A,CPEB3,ANKRD6,WDR47,SLC12A2,SLC14A1,ELMO2,FAM126B,DOP1A,BDP1,TSNAXIP1,HECW1,ZNF423,CLSTN2,SSTR1,ZC4H2,NUDT10,SLC37A2,SATB2,TRIM2,RPGRIP1L,TCF12,FAM189A1,PMS2CL,ZFPM2,SLC44A1,ERCC6L2,PRRT1,RGMB,TTTY15,ZKSCAN5,P2RY12,ZIC1,ZIC2,KCNT2,ZNF225,EMSY,SLC38A1,RNF103,ADAMTS9,PARP11,RGS7BP,FZD3,FBXO36,JMJD1C,RNF170,ZDHHC20,SPATA13,SENP7" MicroRNA hsa-miR-1308:mirSVR_lowEffct hsa-miR-1308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-72 1.53E-68 1.77E-71 1.63E-70 199 1210 "EMILIN3,ADCY6,ADORA2A,ADRA1D,KCTD16,RTL9,KIAA1324,HFM1,CEP126,PCDH10,FAM135A,AMPD2,ANK2,SEMA7A,PKP4,KCNAB2,APOC2,IGDCC4,ARNTL,CADPS,MARK4,CCAR2,STX16,RNF182,BACH1,LINC00847,DST,SCAPER,MTMR3,JAZF1,KALRN,SPAG9,DGKI,LARGE1,UBE2L6,CHN2,CLTC,CNR1,IQCK,SLC4A8,ABI3BP,SLC35F1,SEC31B,CS,RGS6,IPCEF1,VAC14-AS1,CTH,DCAF4,MYADM,ARHGAP32,TCAF1,ZNF337,YTHDC1,JAKMIP2,MFAP3L,KIAA0319,SACS,WDR20,DLX1,DMPK,CDON,DMTF1,EDN1,FCF1,TMTC1,FSD1L,YAF2,MBNL2,AASS,CALCRL,DCTN4,EPB41,EPB41L2,RCAN2,VPS26C,CLVS1,CHST15,ZMYND10,GORAB,HPCAL4,SEC23B,AGAP2,FLT1,ZBED3,UFM1,MEGF10,ALDH1L1,CYP46A1,ADAM28,RNPS1,GRIA2,GRIN2C,GRM2,GSN,MAP4K5,PADI2,MAN1B1,HNF4G,ZDHHC15,TCEAL6,SHISA6,SMAP1,SOWAHA,GAREM2,FAM69A,LRRTM1,ITPKB,GATD1,KIT,GPR155,MAN2A2,MAP6,MBD1,MEIS1,MMP16,ZNF680,TAGLN3,MYO9A,ZC3H12B,NOVA1,DNHD1,GLIPR1L2,DPY19L2P2,PDE3A,CCSER2,NLE1,PCDH18,POLR2F,FSD1,RASGEF1B,RELN,APTX,TMEM260,ZSCAN32,PTPN13,ZSCAN2,NKAIN1,PID1,CEP97,TMEM255A,NWD1,RASGRF2,ZMAT4,GTDC1,SLC25A36,RIC8B,TMLHE,PCMTD2,MRAP2,SNX22,SPIN3,TCP11L1,RYR3,DGLUCY,LRFN5,SCN2B,TNFRSF19,ZFP30,FBXO11,FAM214B,ATF7IP,SMARCA4,SMARCD3,IFT122,SNRPN,DOP1A,TRERF1,DOK5,ARHGAP26,STAU1,SEPT8,CEP68,ADHFE1,PHLDB1,KLHL7,TACR1,SMG6,PCDHB4,OBSL1,ENHO,MTMR14,TLR4,ERCC6L2,TMPO,FAM124A,TPM2,EIF4ENIF1,FLRT2,AGMO,DNALI1,RNF103,HPS4,FZD3,DOCK8,PHTF2,RNF170,SNX14,SOCS4" MicroRNA hsa-miR-208b:mirSVR_lowEffct hsa-miR-208b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.86E-72 1.60E-68 1.84E-71 1.70E-70 166 841 "RALGAPA1,KCNH8,CLK4,NCKAP5,KDM5D,KLHL32,OSBPL1A,HFM1,FAM135A,ZFAT,LRCH2,APC,TNRC6C,ASPA,ATP2A2,ADGRB2,DST,MTMR2,PRMT9,C5,IL33,PTBP2,ISPD,KRIT1,CD38,LRBA,CDH2,NDST3,NRXN3,HECTD1,SLC4A8,ABI3BP,AHCTF1,ZNF521,NRG2,RBM39,RNF14,ANKRD44,GDA,RGS6,SOCS5,FAM131B,HDAC9,ARHGAP32,ARHGAP24,ZFYVE16,YTHDC1,MYEF2,DMD,USP3,DMTF1,E2F5,EBF1,WDPCP,PHF20L1,EIF4G2,TENM1,PLEKHA1,RGS17,SLC43A2,IGSF6,RRAGB,ST3GAL6,ZNF589,FGF13,NELFCD,STAU2,OGA,MEGF10,B4GALNT1,KIAA1841,MSTN,GDF9,GLYR1,PRUNE2,CACFD1,PRDM5,BACH2,MIER3,HLF,IGFBPL1,SHISA6,IL6R,LRRTM1,KCNN3,IPO5,LIG4,LRP1B,MEF2C,SRSF12,NEFH,NELL2,NF1,NOVA1,OCRL,XRN1,GPSM2,SLC25A23,MAPKAP1,ING3,SH3KBP1,DRAM2,PPP3CA,RASGEF1B,MAPK10,MTMR10,PTPRG,PTPRO,PPP2R3C,CEP97,SH3TC2,FAT4,ZCWPW1,RADX,RFX3,ROBO1,ATP8B4,MEG3,RMI1,SALL1,SATB1,FNIP1,SEC14L1,HSPA4L,KIF21A,AMBRA1,FNDC3A,SYBU,SEPHS1,ELMO2,ATF7IP,SMARCC2,DMRTC1,LMBRD1,DOP1A,POGZ,RGL1,DIP2A,KANK1,PRRC2C,VPS13A,DNAJC9,FAM208A,TCF12,SYNE1,PHF24,PCDHB3,FRYL,ITGB3BP,SLC44A1,GALNT17,TP53BP1,RUSC1,PRR18,BCL2L13,REEP1,ANKS1B,MEIS3,INTS3,SLC30A4,EMSY,CADM2,AMN1,FZD3,FBXO36,TRAM2-AS1" MicroRNA hsa-miR-27a*:mirSVR_lowEffct hsa-miR-27a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.11E-72 3.42E-68 3.93E-71 3.62E-70 188 1087 "KDM5D,ADD1,PWWP2A,RNF150,KCTD16,OSBPL1A,KIAA1324,CC2D2A,BBOX1,SYT13,PITPNM2,PPFIA4,PKP4,EPB41L5,FAM131A,TNRC6C,AQP6,MARCH3,NCOA1,DPY19L3,RIPK1,ADAM23,ADGRB2,SCAPER,CBS,USP2,CD86,C1orf52,CDO1,FOXN3,ASIC3,NDST3,RAB28,PPT2,CNTN1,COL9A3,ZNF521,SLC35F1,RNF14,ANKRD44,TRIM69,AATK,RGS6,ARHGEF10,CSNK1G3,PDE4DIP,RIMS2,ARHGAP32,KATNAL2,RIPOR2,RASSF2,ZBTB24,RUSC2,TMEM130,HS3ST2,E2F5,WDPCP,RASGRP1,PHF20L1,MRO,EIF4G1,PLEKHA1,ELN,PAN3,EIF1,HSD17B14,MRPL37,FAM198B,TMEM132C,CHST15,FECH,FGF13,UBE2E3,FLT1,PSD2,KHDRBS3,CELF1,CGREF1,ST6GALNAC3,ZMAT1,DENND2A,IQGAP2,SESN1,ADAM28,GFER,MALT1,BRD8,CRCP,TOX3,STARD3,LNX1,STON1,STMN2,ADAMTS13,NEGR1,KCNN2,CREG2,ASPRV1,PIK3AP1,MBD1,MEIS2,ZNF92,P2RY13,NBL1,NCF2,NEFM,NF1,NFYA,PCBP3,ENPP2,GNG2,PFKFB4,SERPINI1,NALCN,SNX10,PLCL1,MTRF1L,SDK2,TATDN3,VSTM2L,CEP41,GDPD1,RELN,WBP1L,BDNF-AS,CASTOR1,ZSCAN2,TUG1,MARCH1,OXR1,FIGN,RGS12,ROBO1,NEK11,GLDN,MEG3,COPZ1,ARX,FHOD3,SEC31A,WDR37,NBPF1,SEPHS1,SLC12A4,KIF13A,CABCOCO1,ZNF415,SNRPN,KDM4B,USP33,KDM4C,IQSEC2,ZNF621,RGL1,PHLDB1,KANK1,SULF2,SYP,TAL1,ATMIN,ZEB1,TPCN2,SZT2,USP32P1,FRYL,DICER1-AS1,MTMR14,TK2,SYNPO2,PLEKHH2,LAT2,GUSBP1,XRCC4,LGI4,TRIM9,EML6,ZNF189,SPIRE1,FTSJ1,ZNF213,PRDM8,RNF103,GAL3ST3,NAV3,PCBP4,RTN4,CASC15,NETO2" MicroRNA hsa-miR-330-3p:PITA hsa-miR-330-3p:PITA_TOP PITA 6.34E-72 3.55E-68 4.08E-71 3.75E-70 152 703 "ABR,KLHL32,ARHGAP20,GPRASP2,AMPH,OGT,DPP10,APBB2,APC,USP37,CADPS,ZBTB10,RASL11B,ATP2B2,FUBP1,LDLRAD4,CALM1,PTBP2,CAMK2G,CBFA2T2,C1orf52,DCLK1,CCPG1,FOXN3,NRXN3,COL4A5,ABI3BP,GDA,ARHGEF10,OSBPL3,CSNK1G3,KIAA0408,GAPVD1,MAML1,IST1,IP6K1,PITPNC1,YTHDC1,ELMO1,SPOCK3,FAM107B,DLX1,CDON,DPYSL2,DRP2,EDN1,PHC2,APH1A,MBNL2,TENM1,TMEM35A,EPB41L2,GPHN,ERBB4,ETV1,PPP1R1B,SUCO,HPCAL4,AGAP2,AFF2,DCTN2,ST6GALNAC3,PCDH17,TCERG1,KDM2B,GNAO1,PRRC2B,TDRKH,GPR37,GRB10,CIT,RNF165,SOX21,ADAMTS6,MIER3,HSF2,KIF2A,PACRG,MARK1,MAT2A,MBNL1,CHIC1,LRP1B,MEF2C,MN1,BLOC1S2,MYH3,ZC3H12B,PCDH9,PDE1B,PIK3R1,KCTD15,PMP22,LRP12,KANSL1,VSTM2L,PRKAB2,CEP41,MAPK10,PTK2,PTPRD,PTPRO,NKAIN1,USP47,GTDC1,RIC8B,ZFHX4,CCDC112,SALL1,SCN2B,SCP2,GALNT10,TRA2B,PPM1E,KIF16B,SHC4,CHD9,FNDC3A,SLC12A2,RCOR3,PDZRN3,SOX11,SP4,KDM4C,ZNF423,SSTR1,LARP4,ERBIN,STAU1,SULF2,SYNE2,ARHGEF9,PLCB1,SYT5,FBXW11,TBL1X,TCF4,TRIM2,PUM2,DICER1,SIRT1,ZMAT3,TNS1,TRPS1,ZBTB14,REEP1,CADM2,PRDM8,ITM2C,RGS7BP,FZD3,JPH3" MicroRNA hsa-miR-4253:mirSVR_lowEffct hsa-miR-4253:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.50E-72 4.20E-68 4.82E-71 4.44E-70 218 1450 "ABR,AS3MT,ADCY6,GALNT13,USP31,PTCHD1,ADRA1D,ADRB2,OSBPL6,TAOK1,SMIM17,FAM135A,ZFAT,MYH7B,EPB41L5,UPRT,CPNE5,CHID1,ATP1A3,SLC4A4,ATP6V0A1,ADAM23,ADAM15,LINC00847,KSR1,SYNJ2,MTMR2,LURAP1,RUNX1T1,KYAT1,CBFA2T2,EVI5L,CACNA2D2,ASIC3,CHN1,NDST3,NRXN3,FAM19A5,WHRN,RTTN,MYRIP,ZNF385A,CREM,HAPLN1,HINFP,NCOR1,SNCAIP,SUSD5,SOCS5,GREB1,BOC,TBC1D5,IST1,ELMO1,ALKBH8,EXOG,ARRDC4,KRBA2,E2F5,EBF1,EDN3,EDNRB,FSD1L,CELSR3,PHF20L1,SUGP2,EMX2,VPS13B,EPB41L2,LRRC17,SLC43A2,FAM198B,SCML2,OLFM1,FGF11,POLK,UBE2E3,PSD2,FLYWCH1,CINP,ERGIC3,SARAF,HRASLS5,GABRG2,ERAP1,INPP5K,KIAA1841,MSL3,DCLK2,WDFY3-AS2,RNF165,RNFT2,ATOH8,ELOVL5,GABARAPL2,CPT1C,MSL1,ZNF546,GAREM2,SCIN,KCNJ5,A1BG-AS1,LIFR,SFXN5,LIMS1,NCOA7,LSS,MAN2A2,MAP4,MBNL1,ADAM11,MEST,SAMD5,MSR1,N6AMT1,MYO7A,SFR1,NEFH,NEK1,DNHD1,SLC11A2,IGSF11,PFKFB4,ZNF655,FAM216A,PNMA3,SCHIP1,NECAB2,POU6F1,TATDN3,KANSL1,NKAIN4,SAMD9,WBP1L,QRICH1,WDR25,PTCH1,ZIK1,PTPRB,PTPRD,EML5,CASTOR1,PTPRH,TMEM231,USP47,SUSD4,ZNF493,DPF2,RNASEL,KIRREL1,SNX22,NEK11,EPHA10,RPL15,BAALC,TCP11L1,ATAT1,ZNF331,AP1AR,RMI1,DGLUCY,SATB1,SCN7A,CASC3,ASAP3,FBXO11,SLA,SLC11A1,KBTBD4,LGI3,RCOR3,SNRPN,USP33,ZNF423,SPTAN1,IQSEC2,TSPYL2,LHPP,ITPRID2,SAMSN1,SSPO,NXT2,ZSCAN29,SEPT8,ADHFE1,KLHL7,ZC3H4,SYNE2,VPS13A,PLCB1,SYN2,PDLIM2,WSCD1,DMXL2,ZFP90,PHF24,PCDHB3,ZMAT3,ERCC6L2,TPM1,C9orf85,RGMB,SYNPO2,PDSS1,STXBP4,ZKSCAN5,PLEKHH2,ZNF709,TBC1D15,RBFOX3,XRCC4,NDRG4,UPF3A,GDPD5,ADAMTS9,AMN1,PHTF2,FRMD6" MicroRNA hsa-miR-208a:mirSVR_lowEffct hsa-miR-208a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.86E-72 4.40E-68 5.04E-71 4.64E-70 165 836 "RALGAPA1,KCNH8,CLK4,NCKAP5,KDM5D,KLHL32,OSBPL1A,HFM1,FAM135A,ZFAT,LRCH2,APC,TNRC6C,ASPA,ATP2A2,ADGRB2,DST,MTMR2,PRMT9,C5,IL33,PTBP2,ISPD,KRIT1,CD38,CDH2,NDST3,NRXN3,HECTD1,SLC4A8,ABI3BP,AHCTF1,ZNF521,NRG2,RBM39,RNF14,ANKRD44,RGS6,SOCS5,HDAC9,ARHGAP32,ARHGAP24,ZFYVE16,YTHDC1,MYEF2,DMD,USP3,DMTF1,E2F5,EBF1,WDPCP,FSD1L,PHF20L1,EIF4G2,TENM1,PLEKHA1,RGS17,IGSF6,RRAGB,ST3GAL6,FGF13,NELFCD,STAU2,OGA,B4GALNT1,KIAA1841,MSTN,GDF9,GLYR1,PRUNE2,CACFD1,PRDM5,TNFAIP8L3,MIER3,HLF,IGFBPL1,SHISA6,IL6R,LRRTM1,KCNN3,IPO5,LIG4,MATN2,SRSF12,NRBP2,NEFH,NELL2,NF1,NOVA1,OCRL,XRN1,GPSM2,SLC25A23,MAPKAP1,ING3,SH3KBP1,DRAM2,PPP3CA,RASGEF1B,MAPK10,MTMR10,PTPRG,PTPRO,PPP2R3C,CEP97,SH3TC2,FAT4,ZCWPW1,RADX,RFX3,RNASEL,ROBO1,ATP8B4,MEG3,RMI1,SALL1,SATB1,FNIP1,SEC14L1,HSPA4L,KIF21A,AMBRA1,FNDC3A,SYBU,SEPHS1,ELMO2,ATF7IP,SMARCC2,DMRTC1,LMBRD1,DOP1A,POGZ,RGL1,DIP2A,KANK1,PRRC2C,VPS13A,DNAJC9,FAM208A,TCF12,SYNE1,PHF24,PCDHB3,FRYL,ITGB3BP,SLC44A1,GALNT17,TP53BP1,PPIL6,RUSC1,PRR18,BCL2L13,ZNF540,REEP1,ANKS1B,MEIS3,INTS3,SLC30A4,EMSY,CADM2,SLC38A1,AMN1,FZD3,FBXO36,TRAM2-AS1" MicroRNA hsa-miR-1233:mirSVR_lowEffct hsa-miR-1233:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.25E-72 5.18E-68 5.93E-71 5.46E-70 213 1389 "KCNH8,SYN3,AS3MT,PSMG3-AS1,ADD1,ADRA1D,HFM1,C1QTNF3,ZNF687,PDZD4,FGD2,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,KCNAB2,UPRT,MADD,ARRB1,PLA2G4C,CDK13,MARK4,PCDHGB4,NUMB,DPY19L3,TTLL9,NAE1,HAP1,CAST,RUNX1T1,USP6,CDH2,DLGAP2,TIGD7,UBE2L6,HECTD1,COL11A2,RCHY1,COX4I1,GDA,SNCAIP,ARHGEF10,VCAN,PLXNA4,GREB1,FAM131B,DOCK4,ARHGAP24,ZNF337,DAPK1,IP6K1,AIF1L,ZBTB24,KIAA0319,ALKBH8,RHOBTB1,SACS,DLX1,DMPK,HS3ST2,ABCC5,E2F6,PHC2,OPTN,SUGP2,EBI3,VPS13B,COQ7,ZNF391,GMPR2,EZH1,FAM198B,DLC1,FCGR1A,ZNF589,GTF2IRD2,OLFM1,FGF11,EFCAB2,POMT1,STAMBP,ATP6V1H,ERGIC3,ZNF44,KIAA1841,CPLX1,GCNT2,GPR162,COPS8,RAB30,TDRKH,DIDO1,GRIK4,ADAMTS13,GRM2,ZNF496,AP4S1,ATOH8,FRMD3,ATXN2L,SYNPO,HMGCR,C9orf129,ZDHHC15,DHX35,MSL1,FAM95B1,ZNF546,LRRC25,GPR62,KIF5A,CYP27C1,MAN2A2,ZFYVE27,MAP4,MAT2A,CHIC1,SCAMP5,MID1,NBL1,NME4,NUCB2,TBC1D25,CLDN11,GLIPR1L2,PCDHGC3,PCDH9,CDK18,PDCD2,FAM218A,GPSM2,ANKRD16,PPP2R5E,PKIA,MAPK4,MAPK10,DCHS2,PSD,PTPRE,RIPOR1,ZSCAN2,TMEM231,RASGRF1,RET,RFX3,RNASEL,ROBO2,RORB,SNX22,RPL15,BAALC,MCMBP,ADAL,ABCA11P,CSRNP3,SEC14L1,CASC3,SGK1,KIF21A,FERMT1,NUBPL,DHX30,FAM214B,ARFGAP1,CXXC4,ZNF667,SMARCA4,FAM126B,BDP1,IQSEC2,DDN,NFASC,STAU1,SYN2,EXOC7,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PMS2CL,SLC44A1,C9orf85,SMUG1,TRIO,TRO,FAM155A,UGT8,PLEKHH2,WIPF1,RICTOR,LGI4,ATP6V0E2,MKRN3,ZBTB38,DPYSL5,ANKS1B,LAMP5,LINC02210,SIGLEC10,URM1,PPP1R3F,MPPE1,PARP11,TMEM63C,FBXO36,DPF3,FAM198A" MicroRNA hsa-miR-22*:mirSVR_highEffct hsa-miR-22*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.45E-72 5.29E-68 6.05E-71 5.57E-70 210 1352 "CLK4,NCKAP5,INTS2,HECW2,CC2D2A,C1QTNF3,ARHGAP20,LRCH2,ANK2,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,BCAS1,TNRC6C,AQP6,EIF4G3,ATP1B3,TTLL9,FUBP1,CALB1,THSD7A,SLC25A14,CAPN3,CAST,CBLN1,LRBA,ARHGEF2,CDR1,TIGD7,CLTC,NGEF,CNR1,CNTN1,COL9A1,LETMD1,CLOCK,AKAP12,SNCAIP,RGS6,CSF2RA,CSNK1E,SOCS5,PDE4DIP,SLITRK5,ERC2,RIMS2,TCAF1,CENPL,MATR3,PABPC5,JAKMIP2,EXOG,DYNC1I1,NR1D2,DMTF1,DTNA,AASDH,SEMA3D,KLHL5,PHF20L1,EGFR,MRNIP,PAN3,USPL1,EIF1,EPHB1,SRRM1,TLR7,EXTL2,FCGR1A,FCGRT,FDFT1,GORAB,POLK,SUCO,RGPD5,ATP13A4,FLT1,NELFCD,COQ5,EFCAB2,NBEA,PDLIM5,AP4B1,TVP23A,FYB1,GALC,ACSS1,KIAA1841,GATM,SULT1C4,AHDC1,PPARGC1A,ZNF638,RAB40B,GPD2,TDRKH,GPR34,PCLO,BTN2A1,GSTT2,RABL2A,PADI2,NCKAP1L,HMGCL,HNMT,ZDHHC15,ZIC5,RBPJ,LRRCC1,KCNB1,CREG2,LRP1B,MEIS1,DBNL,SAMD5,NOVA1,SLC11A2,NUCB2,TBC1D25,OPA1,PDE4B,GNG2,PFKFB2,NLGN3,TMEM38A,FAM216A,PRIMPOL,EXOSC10,SCHIP1,EPB41L4B,PRKAB2,RASGEF1B,MASP1,ANKHD1,PTK2,PTN,STK32A,EML5,C1orf109,CEP97,ACSS3,RAP1GDS1,GTDC1,RGS3,RIC8B,TMLHE,CARF,CCDC25,ADAL,ATXN2,SCN8A,SCP2,TNFRSF19,FRMPD1,SHC4,FNDC3A,NLGN1,NUBPL,FAM81A,PREX2,WDR47,CCDC88A,BTBD7,CDK5RAP2,MYH15,RCOR3,ANKRD36,GLT8D1,HECW1,KDM4C,SSTR2,LARP4,ERBIN,NXT2,MPRIP,KANK1,SULF2,PRRC2C,SYN2,SYP,CAMTA1,FAM208A,KLHL4,TCEA1,KIAA0930,ZEB1,USP32P1,RIMBP2,TP53BP2,TPM1,NPL,ZNF346,TRIO,TRPS1,SGK3,VLDLR,WRN,ZNF19,ZNF70,CELF4,EML6,UPF3A,EVI5,KCNAB1,FIP1L1,UBE3B,PHTF2,NETO1,JPH3" MicroRNA hsa-miR-455-3p:mirSVR_highEffct hsa-miR-455-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.53E-72 5.33E-68 6.09E-71 5.61E-70 170 890 "KCNH8,FMNL2,ADD2,ADORA2A,ZNF608,OGT,DPP10,PKP4,PARG,TMEFF1,ARRB1,DYNLL1,ATP1B3,N4BP2L1,DOCK11,ADGRB2,KALRN,SPAG9,CCNH,ZBED1,MAGI1,TIGD7,NUMBL,SOCS6,LHX2,CLTC,FBXO7,C4orf33,HECTD1,ARMC8,CNRIP1,FAM171B,ANKRD44,TRIM69,CSF1R,CSNK1G3,SUSD5,PDE4DIP,SLITRK5,CYBB,HDAC9,ZFYVE16,MYEF2,MFAP3L,SNAP91,EDNRA,PHC2,ANKRD46,FCF1,FRY,APH1A,SRPK3,TMEM35A,EIF1,EPB41L2,EPHB1,ETV1,F8,PTK2B,POLR1B,NELFCD,STAU2,MEGF11,GABRG2,KIAA1841,ARFIP1,TOX3,LILRA2,GRIA2,PSIP1,RASSF8,HAS2,FRMD3,TNFAIP8L3,GABARAPL2,AGBL5,IDH3A,FAM69A,KCNJ16,KIF5A,STXBP5,LAMP2,STMN1,PACRG,AFDN,COMMD5,ADAM22,NELL2,NOVA1,NRCAM,IGSF11,PAX6,PCSK5,PDCD2,ABCB1,PIK3R1,RETREG1,PLCB2,JAKMIP1,MAPKAP1,FSD1,PPP2R5E,PPP3CA,GRAMD1C,MASP1,RELN,CNTLN,BDNF-AS,OXR1,HKR1,DPF2,RET,UBR7,PBRM1,CARF,YY1AP1,PCMTD2,ATP8B4,SALL1,SATB1,ATXN7,TNFRSF19,ARX,NLGN1,PEX26,KANSL3,SLC12A2,SLC22A4,ZNF667,CDK5RAP2,RCOR3,CDK19,RBM26,ATP10B,SS18,TTBK2,DIP2A,VPS13A,SYN1,C12orf76,TACR1,DMXL2,ZEB1,RPGRIP1L,SLC19A3,PUM2,SIK3,SIRT1,AP4E1,SLC44A1,ARL10,KAT6B,AMACR,CLDND1,XPO1,MICU3,CELF4,SPIRE1,LAMP5,EMSY,STOX2,SLC17A7,KCNAB1,MPPE1,PLSCR4,RTN4,NHSL1,IFT88,GAN,CPNE4" MicroRNA hsa-miR-4264:mirSVR_lowEffct hsa-miR-4264:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.85E-72 5.51E-68 6.29E-71 5.79E-70 228 1580 "DGCR6,SYS1,GALNT16,ADD2,BRAP,ADORA2A,LRFN2,HACE1,OSBPL1A,SEMA6A,SPOP,FAM135A,AMPD2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,APOC2,TNRC6C,PPFIA3,LGR5,MADD,CHRD,DYNLL1,ATP1A1,ZNF582,DOCK11,ADAM15,SEC11C,PROM1,KSR1,SYNJ2,CASTOR3,SGCE,CA12,CALB1,CAST,CARS,CLDN10,METTL6,USP6,P2RX6,SCARB1,CDC25B,CDH2,FAM189A2,COL9A1,MAGED1,RTTN,CRMP1,ANKRD44,SNCAIP,CST3,GREB1,DGKB,PABPC5,DBI,DNAL1,ARMCX4,PITPNC1,MFAP3L,GSDME,ALKBH8,DMPK,RPS6KL1,CPEB2,DRP2,FCF1,APH1A,KMT5B,TMEM35A,STARD3NL,EPHB1,GPHN,SPEG,PIPOX,ADGRV1,EYA1,F8,ARMCX1,SH3YL1,FCGR1A,ZNF589,GORAB,MEX3B,PCYOX1,NELFCD,ERGIC3,CELF1,DLL3,MPP6,MEGF10,GABRB3,IP6K3,GCNT2,SULT1C4,MSTN,AHDC1,ADAM28,GGTA1P,LYVE1,CRCP,TCERG1,RAB30,STARD3,ZNF638,KDM2B,LPAR4,PCLO,SERP2,RNF165,AP4S1,RASSF8,HNF4G,LRRCC1,FAM69A,ITPKB,KCND2,KIF5A,LAMA2,LAMP2,SYTL4,LYPLAL1,MATN3,MEIS1,MIA2,KITLG,MID1,ADAM22,MYO7A,MYT1,HNRNPM,CCDC13,NF1,ZNF827,GLIPR1L2,SNX10,ZFYVE21,XRN1,KCTD15,SMIM7,MTRF1L,EXOSC10,POLR2F,FSD1,PPP1R1A,RASGEF1B,PRKACB,CEP41,BCAS3,WBP1L,CNTLN,PTPRD,SH3TC2,NWD1,KHDRBS2,ZMAT4,TRIM68,RIC8B,CCDC25,ELP2,MRAP2,MEG3,ABCA11P,RTN1,ZNF354C,ZNF331,AP1AR,CSRNP3,SCN2B,SCP2,TNFRSF19,FOXRED1,FAM102A,KIF16B,CPEB3,FBXO11,FAM214B,PKNOX2,SLC12A2,ELMO2,BTBD7,CPEB4,INAVA,MBD5,MYCBP2,CDK19,RBM26,SPART,ITPRID2,ZC4H2,NEK4,PHLDB1,KANK1,JMJD6,SYP,ANKRD28,TACC1,MTCL1,ADGRL3,CUX2,TRIM2,ARHGAP9,AP4E1,ZNF106,ACTR6,NR2E1,RIMBP2,PIK3R5,SYNPO2,METTL3,ANKRD20A2,TTTY15,UBE2H,BCL2L13,GUSBP1,ZBTB14,MICU3,ZNF28,LYPD6,DHX33,SEMA3B,DOCK8,CASC15,FAM219B,JMJD1C,SNX14,FRMD6,IFT88" MicroRNA hsa-miR-548l:PITA hsa-miR-548l:PITA_TOP PITA 1.08E-71 6.04E-68 6.88E-71 6.34E-70 147 657 "HECW2,ALCAM,FAM135A,CDC42BPA,EP400,APC,GAS7,USP37,PPP4R4,ZBTB10,SYNJ1,FUBP1,MTMR3,JAZF1,LDLRAD4,CALB1,PTBP2,CFL2,SRSF11,FOXN3,SOCS6,CHN2,LHX2,FAM19A5,QKI,CNR1,CNTN1,ARMC8,AHCTF1,SLC35F1,CS,CSNK1G3,PHACTR3,APPL1,PLCXD3,PUM1,RIMS2,USP6NL,DOCK4,ARHGAP24,MYEF2,SACS,RAB39B,CPEB2,DTNA,E2F5,TMTC1,EGR3,PAN3,ERBB4,FGF13,FOXF2,AFF2,NBEA,PDLIM5,FAM49B,MEGF11,GABRB3,ACSS1,CPLX2,ARFIP1,AHDC1,TCERG1,TOX3,MSL3,FAM19A2,BACH2,HLF,HMGCR,IGFBPL1,NEGR1,SOWAHA,JAK2,SFXN5,HECTD2,GPR155,CHIC1,LRP1B,MEIS1,KITLG,MKLN1,MXI1,MYCN,MYO5A,NEXMIF,TCEAL5,NFE2L2,NOVA1,NPTX1,NRCAM,TBC1D25,IGSF11,OCRL,CLDN11,GPR85,PIK3C2A,XRN1,SMOX,PURG,MAPKAP1,STRN3,MAGEL2,DIRAS2,WBP1L,SNRK,PTPN13,TMEM255A,MSANTD2,RDX,REV3L,NUDT11,PBRM1,ZFHX4,AP1AR,FNIP1,HSPA4L,CHD9,CNKSR2,NLGN1,SEPHS1,CPEB4,SNAP25,PDZRN3,SP4,CLASP2,SS18,ANKRD12,RPGRIP1L,SIRT1,ZFPM2,RIMBP2,TNS1,RGMB,STXBP4,FLRT2,BCL2L13,TRIM9,CELF4,REEP1,TMEM237,SLC30A4,EMSY,STOX2,KCNAB1,FAM13C,FXR1,FRMD6" MicroRNA hsa-miR-1243:mirSVR_highEffct hsa-miR-1243:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-71 6.25E-68 7.12E-71 6.56E-70 186 1068 "NDRG3,NDRG2,KIAA1211,DPY19L2P4,SLC24A4,ZNF608,WDR35,HFM1,ADGRF5,C1QTNF3,ABCD2,AMPD3,VAT1L,CADPS,MARCH3,IL33,CA8,PTBP2,CBR1,MTMR7,CDO1,SRSF11,FAM19A5,QKI,CNTN1,AKAP7,COL4A5,GAL3ST1,AHCTF1,FAM171B,CREM,HAPLN1,NCOR1,GDA,SNCAIP,ERC2,PHF14,USP6NL,CCDC144A,CYBB,ARHGAP32,TCAF1,LIN54,PABPC5,BRINP1,MYEF2,DDX46,DMD,DTNA,FSD1L,EGFR,RGS17,TMEM35A,VPS13B,EXTL2,EYA1,CEP78,MED12L,OLFM1,WDR83,SMC2,UFM1,MSANTD4,CHL1,GABRB3,B4GALNT1,PPARGC1A,DBF4,TOX3,STARD3,LUZP2,LNX1,GPD1,PRUNE2,LPAR4,GRIA2,GRIK4,ATE1,PSIP1,MIER3,ZNF546,IL6ST,ITGAM,KCNJ5,KIF5A,STXBP5,TTYH2,NCOA7,SMAD9,MAT2A,MBNL1,PPM1L,AFDN,ZNF680,COL28A1,MYO9A,CCDC13,CNOT4,SLC11A2,NTRK2,GLIPR1L2,PCDH9,PDCD2,NLGN3,SEMA5B,ZNF655,FAM218A,CCSER2,PURG,PRIMPOL,TRHDE,PPP2R2C,SAMD9,VPS13C,PTCH1,TMEM260,PTPRB,EML5,PTPRE,PTX3,OXR1,RADX,RET,SLC25A36,NUDT11,ZFHX4,CCDC82,GSTCD,CCDC102B,RPE,RPS6KA2,LRRK2,RMI1,SALL1,FNIP1,HKDC1,FBXO11,CCDC88A,ATF7IP,TET1,ZFP1,CXXC4,DMRTC1,RCOR3,SNCA,SNRPN,HECW1,ATP10B,SSTR1,SS18,RGL1,KLHL7,ZC3H4,PRRC2C,SYN2,SYT1,ANKRD12,MTCL1,KLHL4,ZEB1,PCDHB4,FRYL,TMEM9,TLR4,ERCC6L2,TMPO,BEX4,NPL,WBP2,SMUG1,SSBP2,VSNL1,WIPF1,ZNF781,ZNF32,KCNT2,PRDM8,ADAMTS9,GAL3ST3,NAV3,WNK3,NELFE,EPM2A,RGS7BP,UBE3B,FRMD6" MicroRNA hsa-miR-3153:mirSVR_highEffct hsa-miR-3153:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-71 7.69E-68 8.75E-71 8.05E-70 213 1392 "ASIC1,METAP1D,FMNL2,AXIN2,BRAP,SPOP,ALCAM,ARHGAP20,MARCH4,LRFN1,EP400,APLP1,CADPS,ZNF582,N4BP2L1,ATP6V1G2,RGS9,SYNJ2,FUBP1,JAZF1,CACNA1G,CACNA1A,THSD7A,KALRN,VXN,NFS1,CBLN1,ZNF501,CCNH,MTMR7,LRBA,LRRFIP1,LARGE1,SRSF11,CHN2,EPS15L1,RAB33A,FAM189A2,ARHGEF6,CNTN1,COL11A2,MAGED1,GAL3ST1,RTTN,TOGARAM2,ZFP28,CNRIP1,ENTPD4,CRMP1,ANKRD44,TRIM69,CS,DZIP3,ERC2,PHF14,ZSCAN23,GAPVD1,IST1,TMEM170A,ARMCX4,MYEF2,DDX46,DMD,DMTF1,DPP6,EDN1,FRY,FSD1L,YAF2,PHF20L1,EGFR,PAN3,DCTN4,MRVI1,EZH1,F5,RPS6KC1,PTK2B,CORO2B,DLC1,ZSCAN30,STRADA,SLC9B2,OLFM1,FGF11,IQCG,TPK1,ST6GALNAC3,MEGF10,GABBR1,FAM120B,TMEM8B,MTHFD2,DISC1,GGT7,PPARGC1A,CBX1,GNAL,LNX1,TDRKH,GRIA2,PLCD4,GSTT2,ADAMTS6,ATXN2L,ARHGAP36,NEGR1,LRRC75A,STXBP5,HECTD2,MARK1,LYPLAL1,MAT2A,MSI1,RTL5,NEFH,NF1,NOVA1,DNHD1,SLC11A2,SETD4,CLDN11,PCSK1,PDE4B,NALCN,FAM218A,PURG,MAPKAP1,LRP12,PSAT1,MBOAT7,SH3KBP1,POLR2F,IRX1,PRKACB,PKIA,HYDIN,RELN,BCAS3,SNRK,WDR25,PTN,PTPRB,PTPRO,PEX2,PID1,SH3TC2,FAT4,RAP1GDS1,ZDHHC14,GAL3ST4,DPF2,RET,EXD2,CARF,ATP8B4,ATAT1,RTN1,NCBP3,SEC14L1,CPEB3,ARHGEF40,SLC9A5,NAPB,ZFP1,SMARCC2,INTS9,LIMCH1,MBD5,ANKFN1,SNRPN,PDZD2,KDM4C,LMO3,ZC4H2,TTBK2,ADHFE1,PHLDB1,KANK1,ARHGEF9,TMEM150C,SYN2,ANKRD28,MMS19,TACC1,RPGRIP1L,PCDHB4,PUM2,FRYL,RNF175,ZMAT3,TIAM1,BHLHB9,ERCC6L2,TPM1,STXBP4,DCBLD1,ZKSCAN5,GORASP1,ZNF709,VLDLR,WIPF1,GUSBP1,LGI4,ZIC2,ZNF32,MKRN3,DHX33,PRDM8,NAV3,AMN1,ST7,NHSL1" MicroRNA hsa-miR-4325:mirSVR_highEffct hsa-miR-4325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-71 8.45E-68 9.61E-71 8.84E-70 173 925 "TMCC3,UNC5A,PWWP2A,KIAA1211,INTS2,PCDH19,OSBPL6,TXNDC16,ABCD2,MARCH4,OGT,DPP10,ARNTL,ALDH7A1,ADAM23,RGS9,BCL7A,HCN2,SYNJ1,CACNB4,KALRN,CAST,SPAG9,PRC1,CDH2,LOC730101,NOG,RAB33A,NRXN3,CLTC,HECTD1,MYRIP,CSF1,OSBPL3,SOCS5,PDE4DIP,CTH,USP6NL,RIPOR2,TMEM170A,DAPK1,DBI,PITPNC1,ZNF804A,RHOBTB1,DMPK,NR1D2,CPEB2,CNNM1,FRY,PHF20L1,EIF4G2,PCOLCE2,TMEM35A,VPS13B,RCAN2,SRRM1,EXTL2,CLVS1,DLC1,SEC24B,POLR1B,PRKAG2,POLK,UBE2E3,JKAMP,ATP6V1H,ZNF605,KHDRBS3,ST6GALNAC3,NSG1,OGA,GAA,IQGAP2,GATM,ADAM28,LYVE1,POLL,PCLO,PRDM5,FAM19A2,FAM222A,ZDHHC15,MSL1,FAM69A,SLC35G1,KCND2,KIF5A,MAP4,MARK1,MN1,ADAM22,NEXMIF,NBL1,NEFH,NF1,NPTX2,NRCAM,NTRK2,NTRK3,OXTR,P2RY1,GPR137C,GPR85,PIK3R1,ANKRD16,STRN3,PPP3CA,PPP3CC,CEP41,BCAS3,STRC,TMEM255A,SH3TC2,ZNF493,DPF2,FIGN,RGS3,ZFHX4,LGI2,SETD5,RPL15,FBXW7,GLDN,LRRK2,ABCA11P,RTN1,TRAPPC13,AP1AR,FNIP1,CHD9,ZNF430,ANKRD36,SNAP25,SNRPN,DOP1A,PDZD2,MYCBP2,TROVE2,ITPRID2,SSTR2,SEPT8,CEP68,DIP2A,NECAB1,NUDT10,SYPL1,TCF4,SYNE1,DOCK9,PCDHB3,PUM2,AP4E1,TLR4,SYNPO2,TRO,TRPS1,TTTY15,SGK3,UBE3A,PLEKHH2,PCDH20,ZIC1,KCNT2,MKRN3,ZXDA,PRDM8,FZD3,DOCK8,PHTF2,JMJD1C,NETO1,SENP7" MicroRNA hsa-miR-498:mirSVR_highEffct hsa-miR-498:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-71 9.99E-68 1.13E-70 1.04E-69 179 992 "ADD1,BRAP,MTUS1,OSBPL1A,WDR35,ALCAM,MARCH4,FAM135A,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PKP4,BCAS1,CDK13,NCOA1,NUMB,BACH1,SYNJ2,NAE1,BTK,SGCE,C5,WASF1,CACNA1A,VXN,CAST,SLC16A4,CCPG1,RAB28,IQCK,AKAP6,LETMD1,AHCTF1,RBM39,RNF14,CSF2RA,PDE4DIP,DZIP3,RUBCN,DOCK4,KATNAL2,RIPOR2,PABPC5,RHOBTB1,PLPPR4,SV2B,GRIN3A,DMD,HS3ST2,DTNA,DTNB,EDN3,RASGRP1,PAN3,STX2,EYA1,ACSL4,FGF1,AMOTL2,PRKAG2,MEX3B,SLC37A3,SMC2,RASL10A,CELF1,CSPG5,SARAF,MEGF10,HRASLS5,DISC1,GATM,MALT1,COPS8,DBF4,SPIN1,TNRC6A,FERMT2,GRIA2,FAM19A2,LINGO1,GUCY1B1,HAS2,GABARAPL2,HNF4G,DHX35,IRF8,MSL1,RBPJ,SCIN,ZNF678,INPP1,KCND2,STXBP5,HECTD2,SMAD1,MAP4,MARK1,MATN3,LRP1B,MEIS1,KITLG,NCAM2,NCF2,OPA1,DPY19L2P2,PCDH9,PDE4B,PIK3R1,CCSER2,XRN1,PCDH18,PURG,PPM1B,PPP3CA,KANSL1,PRKACB,CEP41,MAPK9,GRAMD1C,RELN,SNRK,PTPRE,PEX2,TTC13,OXR1,ERI2,PBRM1,ZNF532,EXD2,GSTCD,ADAL,LRFN5,SCP2,HES6,TNFRSF19,HKDC1,FNDC3A,ST6GAL1,NLGN1,BTBD3,WDR47,FAM214B,PKNOX2,BTBD7,MYH15,SNAP25,MBD5,TRERF1,BDP1,LMO3,ITPRID2,ZNF302,LARP4,NKAIN2,SEPT8,COBL,ANKRD28,C12orf76,TACC1,MTCL1,CAMTA1,TAF9,SIN3B,NAT16,FAM200B,DICER1,AP4E1,MTMR14,ACTR6,TP53BP2,AMACR,RPRM,BCL2L13,XRCC4,PCDH20,ZNF28,KCNT2,TMEM237,ANKS1B,CADM2" MicroRNA hsa-miR-4271:mirSVR_highEffct hsa-miR-4271:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-71 1.00E-67 1.13E-70 1.04E-69 186 1071 "ABCF1,ASIC1,EMILIN3,ADCY6,ADRA1D,ADRB2,CC2D2A,SMIM17,PI16,SHROOM2,ARNTL,PCDHGB4,ATP6V0A1,MYOM1,TTLL9,SGCE,CA12,CAMK2B,VXN,SPAG9,CBFA2T2,LRBA,ARHGEF2,ZMYM4,LARGE1,PLEKHB1,CNOT8,NRXN3,PLAA,PPT2,ARHGEF6,AKAP7,SUMF2,SMARCAL1,IGDCC3,FAM171B,SEC31B,PREPL,RNF14,HINFP,CLIP3,SNCAIP,DZIP3,PUM1,MYADM,ARHGAP24,DGKB,DGCR5,SPOCK3,CDON,DPH1,DPP6,SLC25A18,DTNB,DUSP9,SNX29,EDN1,PHC2,TMEM35A,SRRM1,ERBB2,MRPL10,SIRPB1,F5,ACSL4,PTK2B,TAOK3,CORO2B,PPP1R1B,GORAB,FER,FHL1,POLK,SMC2,PDLIM5,ATP6V1H,ERGIC3,STAU2,HHIPL1,GABBR1,HRASLS5,GABRA3,GALNT15,B4GALNT1,IGSF5,TUBA8,MMADHC,GLI2,TNRC6A,CCDC184,PLCD4,GSTM5,KAT7,LINGO1,FAM107A,ATXN2L,ARHGAP36,HNMT,HSPA1L,CELF5,RBPJ,IL6R,ZNF678,ITGA7,MAT2A,SCAMP5,GIT1,NOVA1,DNHD1,NTRK3,IGSF11,PCDHGC3,PCSK5,CDK18,PFKFB2,TMEM38A,PURG,SEPT4,MBOAT7,PILRA,POLG,SH3KBP1,POLR2F,PPP3CC,PRKACB,MAPK10,HYDIN,DCHS2,BCAS3,RASGRF1,RASGRF2,ZDHHC14,GTDC1,LGI2,RPL15,TCP11L1,NCBP3,FOXRED1,SH3GL3,FNDC3A,R3HDM2,PPP4R3A,FAM214B,KDM4D,SIRT2,SLC9A5,SNRPN,ZNF423,SPTAN1,IQSEC2,DDN,NFASC,POGZ,MPRIP,SEPT3,PLCB1,SYN2,MMS19,DNMBP,SMG6,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB6,THRA,TIAM1,R3HDM1,RUSC1,UGT8,AGMO,MKRN3,CELF4,MEIS3,ST7,KAT6A,JMJD1C,PRRT4,JPH3" MicroRNA hsa-miR-4319:mirSVR_lowEffct hsa-miR-4319:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.79E-71 1.00E-67 1.13E-70 1.04E-69 213 1394 "ACADM,ACHE,SYS1,NDRG3,ADD1,LRFN2,BEND6,MTUS1,TXNDC16,CC2D2A,MARCH4,PI16,PKP4,KCNAB2,APC,AQP6,SPTBN4,SLC4A4,SLC2A11,DOCK11,CFLAR,KSR1,SCAPER,CACNA1B,DDR1,ISPD,ARHGEF1,SCARB1,ARHGEF2,CBARP,RAB33A,RAB28,ARHGEF6,AKAP7,ANKRD35,SUMF2,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,SIPA1L1,APPL1,PHF14,GREB1,FAM131B,CCDC144A,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,HEPH,RUSC2,ZC3H11A,RPS6KL1,DPH1,DTNA,DTNB,ABCC5,PHC2,CNNM1,PHF20L1,TMEM132E,PLEKHA1,MRPL10,ANKMY1,SCML2,FCGR1A,FKTN,ZNF589,FER,PRKAG2,SMC2,HHIPL1,AP4B1,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,GGT7,CRCP,TCERG1,ZNF638,LILRA2,CCDC184,LPAR4,TMEM121B,PCLO,GRB10,GRIA2,SPACA9,RASSF8,TOX2,PADI2,MAN1B1,TNFAIP8L3,SYNPO,HMGCR,HNF4G,NKD1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KHK,SYTL4,HECTD2,NCOA7,MAP2,MAP6,MARK1,ADAM11,MIA2,MSI1,MYO7A,NCAM2,NEFM,NUCB2,SETD4,IGSF11,DPY19L2P2,ZDHHC8,ZNF655,RETREG2,POLG,MINDY2,PPM1B,MAPK10,VPS13C,PTH1R,PTK2,PTPRE,C1orf109,FAT4,ZDHHC14,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,ATP8B4,STK32B,EMID1,LRRK2,MEG3,SCP2,CASC3,KIF16B,MYO18A,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,LGI3,ABTB1,ANKRD36,SNRPN,DOP1A,GLT8D1,ZC3H13,SPTB,NFASC,SS18,ELOVL4,SEPT8,ADHFE1,SEPT3,SYN2,SYPL1,SLC37A2,TACR1,SATB2,RPGRIP1L,DICER1,GPR161,AKTIP,BHLHB9,LRRC8A,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,BCL2L13,ELFN1,CRB2,LYPD6,TMEM198,EML6,STOX2,ADAMTS9,SLC17A7,PLSCR4,PARP11,UBE3B,TMEM63C,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-541*:mirSVR_highEffct hsa-miR-541*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-71 1.12E-67 1.26E-70 1.16E-69 217 1445 "CLK4,NCKAP5,SYS1,KDM5D,GALNT13,ADD1,AXIN2,PCDH19,KIAA1324,TXNDC16,AK2,SPOP,ALCAM,ABCD2,ANK2,PHF12,ARNTL,ARRB1,NUMB,ZNF582,N4BP2L1,TTLL9,BCL7A,BMPR1B,JAZF1,PRMT9,IL33,USP6,SLC16A4,LRRFIP1,SRSF11,B4GALT6,PLAA,ARMC8,SLC4A8,RTTN,HAPLN1,HINFP,ANKRD44,CS,MROH8,VCAN,PLXNA4,CTH,HDAC9,ZFYVE16,LONRF1,TBC1D5,DGKB,ARMCX4,SGSM2,FAM107B,NR1D2,DPYSL2,DTNA,FAM78B,DNAJB6,DNM1L,E2F6,EDNRB,ANKRD46,FRY,FSD1L,OPTN,KMT5B,COPS4,CALCRL,PAN3,EMX2,VPS13B,F5,CLVS1,ZNF461,SH3YL1,CEP78,FCGR3A,FGF14,ATP13A4,ANKFY1,SMC2,CAMKK2,ATP2C1,ST6GALNAC3,HRASLS5,GABRG2,DISC1,TUBGCP4,ARFIP1,PCDH17,PPARGC1A,BRD8,GLYR1,ZNF638,GNAL,LPAR4,GRIK4,ZNF496,MAP4K5,FRMD3,GABARAPL2,SMAP1,DISP2,KCNN3,KIF2A,STXBP5,KTN1,SFXN5,HECTD2,MAP4,MATN2,TM6SF1,MEIS2,SRSF12,MMP16,MSR1,DNHD1,SETD4,IGSF11,CNTN3,PAX6,PCDH9,CDK18,PDE1C,OLA1,PIK3C2A,GPSM2,PCDH18,MTRF1L,TRHDE,PSAT1,ING3,EPB41L4B,DRAM2,PPP2R5E,RANBP3L,MAPK7,VPS13C,CNTLN,PTPRE,TMEM255A,FAM66C,FAT4,RFX3,RGS12,KCTD17,RNASEL,CCDC82,CARF,PCMTD2,RPL15,BAALC,ZC3H14,ADAL,PTGR2,RTN1,ZNF331,AP1AR,RMI1,ATXN7,SCN7A,FNIP1,CASC3,SGK1,PPM1E,FNDC3A,PREX2,EPN2,WDR47,SLC8A1,BTBD7,ATF7IP,BDP1,ZC4H2,APOM,NECAB1,JMJD6,PRRC2C,VPS13A,FBXW11,SATB2,TCF12,PCDHGB7,SYNE1,PCDHB6,PCDHB3,PUM2,RNF175,ITGB3BP,AP4E1,TMPO,KAT6B,PIK3R5,TPM2,AMACR,SSBP2,ZKSCAN5,UBE3A,PLEKHH2,USP1,ZNF781,ZNF708,MICU3,ZNF138,FSTL5,ZNF189,ANKS1B,DHX33,EMSY,ADAMTS9,FAM47E,WNK3,PDSS2,HNRNPA3,TIGD6,MSRB3,FRMD6,ST8SIA2" MicroRNA hsa-miR-518a-5p:mirSVR_highEffct hsa-miR-518a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-71 1.17E-67 1.32E-70 1.22E-69 207 1321 "METAP1D,XKR4,PLEKHH1,ADRB2,MTUS1,KLHL13,PCDH19,SRPX,DPP10,PHF12,APBA2,EPB41L5,CDC14B,CDK13,STK33,ZNF583,ADAM23,KSR1,DST,SYNJ2,SCAPER,MTMR2,CA12,CALM1,PRC1,MAGI1,CNGA3,AKAP7,FAM149A,ZNF521,ZFP28,CNRIP1,CLOCK,ENTPD4,RNF14,GDA,ARHGEF10,SOCS5,ERC2,PHF14,CTH,PUM1,DOCK4,IST1,DAPK1,IP6K1,PITPNC1,FBXL5,WDR20,CHRDL1,MED12,NR1D2,DPYSL2,GOLT1B,AASDH,EDN3,EDNRA,PHF20L1,MBNL2,KMT5B,EGR3,EIF4G2,PLEKHA1,PAN3,ENO2,VPS13B,NCALD,TLR7,EYA1,F5,CLVS1,ACSL4,DLC1,CEP78,GORAB,SLC9B2,FGF12,FGF13,FGF14,FOXO3,C2orf88,NBEA,ATP2C1,ST6GALNAC3,NSG1,DLL3,CPLX1,GATM,MSTN,ADAM28,PPARGC1A,MSL3,FERMT2,FUT10,GPR12,ATP2B1-AS1,DIDO1,SOX21,IRAK3,RASSF8,MIER3,SHISA6,SMAP1,IRF8,ZNF181,ZNF678,KCND2,KCNN3,KIF5A,KIT,IPO5,STXBP5,LIMS1,ZNF667-AS1,MBD1,MBNL1,MEF2C,SRSF12,BLOC1S2,MYCN,NF1,NOVA1,TBC1D25,GPR85,PFKFB4,NALCN,PIK3C2A,JAKMIP1,SMOX,PMP22,MAPKAP1,SEPT4,MBOAT7,EPB41L4B,PPM1B,PPP2R5E,PRKACB,PRKCB,QRICH1,PTPRG,TMEM255A,SLC25A48,CCDC40,SH3TC2,RET,GTDC1,KCTD17,NUDT11,CCDC82,ROBO1,ELP2,FBXW7,BAALC,SPIN3,STK32B,MAP6D1,ATAT1,CLIP1,TRAPPC13,AP1AR,SALL1,SEMA6D,SCP2,CASC3,CHD9,FNDC3A,FHOD3,WDR47,SEPHS1,CPEB4,RCOR3,LIMCH1,HECW1,SPP1,KDM4C,LHPP,ZNF302,ZC4H2,PRRC2C,SYNE2,VPS13A,SYPL1,SLC37A2,FBXW11,TCF4,SATB2,ZEB1,TCF12,SYNE1,SLC19A3,PCDHB4,TEK,ZFPM2,BHLHB9,TMPO,C9orf85,RGMB,TRO,P2RY12,AGMO,MFF,ADAMTS9,RGS7BP,FAM13C,PHTF2,ADAMTSL3,SENP7" MicroRNA hsa-miR-527:mirSVR_highEffct hsa-miR-527:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-71 1.17E-67 1.32E-70 1.22E-69 207 1321 "METAP1D,XKR4,PLEKHH1,ADRB2,MTUS1,KLHL13,PCDH19,SRPX,DPP10,PHF12,APBA2,EPB41L5,CDC14B,CDK13,STK33,ZNF583,ADAM23,KSR1,DST,SYNJ2,SCAPER,MTMR2,CA12,CALM1,PRC1,MAGI1,CNGA3,AKAP7,FAM149A,ZNF521,ZFP28,CNRIP1,CLOCK,ENTPD4,RNF14,GDA,ARHGEF10,SOCS5,ERC2,PHF14,CTH,PUM1,DOCK4,IST1,DAPK1,IP6K1,PITPNC1,FBXL5,WDR20,CHRDL1,MED12,NR1D2,DPYSL2,GOLT1B,AASDH,EDN3,EDNRA,PHF20L1,MBNL2,KMT5B,EGR3,EIF4G2,PLEKHA1,PAN3,ENO2,VPS13B,NCALD,TLR7,EYA1,F5,CLVS1,ACSL4,DLC1,CEP78,GORAB,SLC9B2,FGF12,FGF13,FGF14,FOXO3,C2orf88,NBEA,ATP2C1,ST6GALNAC3,NSG1,DLL3,CPLX1,GATM,MSTN,ADAM28,PPARGC1A,MSL3,FERMT2,FUT10,GPR12,ATP2B1-AS1,DIDO1,SOX21,IRAK3,RASSF8,MIER3,SHISA6,SMAP1,IRF8,ZNF181,ZNF678,KCND2,KCNN3,KIF5A,KIT,IPO5,STXBP5,LIMS1,ZNF667-AS1,MBD1,MBNL1,MEF2C,SRSF12,BLOC1S2,MYCN,NF1,NOVA1,TBC1D25,GPR85,PFKFB4,NALCN,PIK3C2A,JAKMIP1,SMOX,PMP22,MAPKAP1,SEPT4,MBOAT7,EPB41L4B,PPM1B,PPP2R5E,PRKACB,PRKCB,QRICH1,PTPRG,TMEM255A,SLC25A48,CCDC40,SH3TC2,RET,GTDC1,KCTD17,NUDT11,CCDC82,ROBO1,ELP2,FBXW7,BAALC,SPIN3,STK32B,MAP6D1,ATAT1,CLIP1,TRAPPC13,AP1AR,SALL1,SEMA6D,SCP2,CASC3,CHD9,FNDC3A,FHOD3,WDR47,SEPHS1,CPEB4,RCOR3,LIMCH1,HECW1,SPP1,KDM4C,LHPP,ZNF302,ZC4H2,PRRC2C,SYNE2,VPS13A,SYPL1,SLC37A2,FBXW11,TCF4,SATB2,ZEB1,TCF12,SYNE1,SLC19A3,PCDHB4,TEK,ZFPM2,BHLHB9,TMPO,C9orf85,RGMB,TRO,P2RY12,AGMO,MFF,ADAMTS9,RGS7BP,FAM13C,PHTF2,ADAMTSL3,SENP7" MicroRNA hsa-miR-212:mirSVR_highEffct hsa-miR-212:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.59E-71 1.45E-67 1.63E-70 1.50E-69 175 950 "ACADM,NCKAP5,AXIN2,PWWP2A,KIAA1211,ESYT2,CC2D2A,SEMA6A,PCDH10,PHF12,APAF1,DDO,SEMA4G,TMEFF1,PDE8B,RNF182,FUBP1,CACNA1G,CACNA1B,PTBP2,SLC25A14,HIP1R,DGKI,LRBA,CDC25B,LRRFIP1,LARGE1,CFL2,RAB28,FBXO7,ARMC8,ZNF521,HAPLN1,ABCG1,CSF1,DOCK4,RIPOR2,KIAA0586,ELMSAN1,ZBTB24,ALKBH8,RHOBTB1,DMD,DTNA,E2F5,EDNRA,CELSR3,PHF20L1,KMT5B,EPB41,DENND4A,NCALD,CDKL3,EXTL2,CEP78,PRKAG2,FOLR2,TPK1,ATP6V1H,ZNF605,ST6GALNAC3,RAPGEF6,ERAP1,INPP5K,SULT1C4,AHDC1,GHR,MSL3,CBX1,GRIA2,SPACA9,ATE1,FAM19A2,HAS2,SMAP1,EID2B,MSL1,SOWAHA,TJAP1,ZNF678,NME9,KTN1,LIMS1,SYTL4,PACRG,PIK3AP1,MEIS1,MEIS2,ADAM22,ZNF862,HNRNPM,NFE2L2,NOVA1,NRCAM,NTRK2,IGSF11,PRTG,SLC10A4,CCSER2,JAKMIP1,MAPKAP1,ING3,EPB41L4B,PPP2R5E,MAPK3,HYDIN,RELN,SNRK,MTMR10,PTPRD,PEX2,FAM184A,ENOX1,OXR1,RADX,KHDRBS2,GAL3ST4,GTDC1,RFX3,ZFHX4,SETD5,EXD2,SALL1,CSRNP3,ATXN7,SEC14L1,ARX,SEC31A,FAM81A,EPN2,SEPHS1,ARHGEF40,SLC12A2,MTERF2,RCOR3,LIMCH1,FNBP1,MYCBP2,CDK19,POGZ,SS18,ERBIN,SEPT8,SYNE2,VPS13A,MMS19,DNMBP,ADGRL3,AGTPBP1,TBCEL,PCDHB6,PUM2,SIRT1,AP4E1,SLC44A1,RGMB,TRIO,NEIL2,TSN,HIRA,SGK3,PLEKHH2,WIPF1,ZBTB14,ZNF708,NDRG4,CELF4,TMEM178A,RGS7BP,FAM13C,RTN4,CASC15,FXR1,FRMD6,IFT88" MicroRNA hsa-miR-613:mirSVR_highEffct hsa-miR-613:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.61E-71 1.46E-67 1.64E-70 1.51E-69 185 1062 "RALGAPA1,ABHD6,KDM5D,NDRG3,CCDC85A,HACE1,ALCAM,ARHGAP20,OGT,CCDC146,MAP4K3,SUGT1P4-STRA6LP-CCDC180,UPRT,ZNF582,BMPR1B,SYNJ1,FUBP1,CA8,KALRN,CAST,MTMR7,L3MBTL4,MAGI1,UBE2L6,SOCS6,CLCN3,CLTC,C4orf33,CNN3,COL9A1,SLC4A8,BAG4,SLC35F1,CREM,RNF14,CRYM,PDE4DIP,MATR3,KCTD8,DGKB,DAPK1,GIT2,YTHDC1,ELMO1,TIAM2,PLPPR4,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,FAM13A,MRO,KMT5B,EMX2,EPHB1,RABEPK,MRPL37,CDKL3,ADGRV1,DLC1,CEP78,FER,FGFR1,SEC23B,IP6K2,NELFCD,NBEA,SPECC1,UFM1,ST6GALNAC3,FYB1,GABRA3,DENND2A,HIGD1B,LRRC37A6P,KIAA1841,TUBGCP4,ARFIP1,PCDH17,PPARGC1A,FERMT2,WDFY3-AS2,ADGRA3,GPD2,MCHR1,RNF165,PSIP1,HLF,HMGCR,ZDHHC15,EID2B,IGF1,RBPJ,INSM1,SLC35G1,METTL21A,KIF2A,KTN1,LAMP2,MAP2,MEIS1,MYO9A,IGSF11,ZNF713,GPR137C,PDCD2,ENPP2,NALCN,PURG,TRHDE,SCHIP1,MINDY2,PRKACB,MAPK3,GRAMD1C,TMEM260,ZIK1,PTPRG,FAM66C,MSANTD2,CRTAC1,ZMAT4,UBR7,SLC25A36,NUDT11,C12orf49,CARF,FBXW7,KCNIP3,RYR3,SEMA6D,SCP2,MRAS,TRA2B,SH3GL3,FNDC3A,ANKRD6,PEX26,SLC6A11,SLC8A1,ELMO2,TET1,ANKRD36,SNAP25,SNRPN,USP33,SP2,SAMSN1,LARP4,SS18,NXT2,SYN2,TACR1,ALG1,KLHL4,SATB2,TRIM2,CLASP1,OBSL1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,TIMP4,LRRC8A,NPL,TRIO,AMACR,TTC3,RPL7L1,FAM155A,UBE2H,UGT8,TBC1D15,TMEM178A,HPS4,WNK3,PARP11,ADAMTSL3,TIGD6,MSRB3,NETO2" MicroRNA hsa-miR-1251:mirSVR_lowEffct hsa-miR-1251:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.52E-71 2.53E-67 2.85E-70 2.62E-69 188 1100 "ACADM,NCKAP5,SYS1,FMNL2,GALNT13,ADD2,BRAP,NME5,WDR35,ARHGAP20,UNC79,OGT,DPP10,FGD2,PKP4,APBB2,SHROOM2,AQP6,RGS20,NUMB,TMEM108,CA12,CALB2,KALRN,PTBP2,SLC25A14,CAPN3,CAST,HIP1R,CCNH,L3MBTL4,NDST3,FBXO7,C4orf33,CNR1,AKAP6,CABP1,LETMD1,MAGED1,AKAP12,HINFP,SNCAIP,IPCEF1,MYADM,LIN54,MAML1,YTHDC1,POM121,SV2B,ZNF582-AS1,DMD,DYNC1I1,DPYSL2,PDCD6IP,ARRDC4,MAMLD1,ABCC5,DNM1L,FCF1,CNNM1,YAF2,KMT5B,EIF4G2,DCTN4,SH3YL1,CHST15,STRADA,FGF12,SYNCRIP,UFM1,CELF1,HRASLS5,ZNF44,GGT7,TOX3,GLUL,STARD3,ZNF782,GPD2,GRIA2,GRIN2C,CLASRP,RNF165,VSIG4,LRRC75A,SOWAHA,IGF1,TJAP1,INPP5B,KCNN2,KIF5A,IPO5,SYTL4,HECTD2,MAN2A2,MAP2,MAP6,AQP11,SAMD5,HS6ST3,NF1,NFE2L2,DNHD1,CYTL1,CCSER2,FAM216A,PLCL1,JAKMIP1,ANKRD16,PDZRN4,SCHIP1,MINDY2,PPP2R2C,RANBP3L,NCR3LG1,BDNF-AS,TUG1,PPP2R3C,CEP97,RAP1GDS1,RASGRF2,RBBP6,GTDC1,KLHDC8A,SPIN3,GLDN,MAP6D1,AP1AR,SUPT20H,COPZ1,SH3BGR,KIF21A,HKDC1,DZIP1,ABLIM3,SLC6A11,ARHGEF40,MAPKBP1,MBD5,CMTR2,SNRPN,SOX11,KDM4C,ZC3H13,TSPYL2,RBM26,NFASC,CLASP2,POGZ,SSTR2,ELOVL4,PLCB1,C12orf76,TPCN2,SYNE1,AP4E1,ENHO,ACTR6,KAT6B,PIK3R5,RGMB,SMUG1,DCBLD1,TTTY15,FAM155A,LINC00689,FLRT2,BCL2L13,ZNF711,TRIM9,ATP6V0E2,SPHK2,ZNF138,ZNF142,REEP1,DHX33,NT5M,PPP1R3F,MPPE1,EPM2A,RTN4,TMEM63C,FBXO36,CASC15,ACTR3B,ADAMTSL3,FRMD6,SOCS4" MicroRNA hsa-miR-759:mirSVR_highEffct hsa-miR-759:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.30E-71 2.97E-67 3.34E-70 3.07E-69 169 889 "CLK4,NCKAP5,NDRG3,PLEKHH1,ADRA1D,OSBPL1A,ALCAM,UNC79,APC,BCAS1,IGDCC4,CADPS,LINC00173,STK33,ZBTB10,DPY19L3,MYOM1,ADGRB2,CFLAR,FUBP1,CA12,CACNA1B,KALRN,SCARB1,C1orf52,LRRFIP1,CDO1,CCPG1,SRSF11,PLAA,CLTC,FBXO7,FAM149A,AKAP6,SUMF2,SEC31B,VCAN,CYBB,RIPOR2,DCAF8,MATR3,BRINP1,GSDME,USP3,SLC25A18,FRY,PHF20L1,RASA4,PAN3,RABEPK,MRPL10,IQCG,PSD2,SYT3,NELFCD,FAM49B,NSG1,RAPGEF6,ZNF559,DISC1,TUBA8,PCDH17,GGT7,MALT1,LYVE1,COPS8,GPD2,PCLO,SOX21,ZHX1,ZDHHC15,DISP2,INPP5B,SLC6A17,KCNH2,IPO5,CYP27C1,NCOA7,MBNL1,SRSF12,MMP16,MYT1,ZC3H12B,NELL2,CNOT4,NTRK2,NTRK3,GPR137C,GLIPR1L2,ZNF426,PURG,MAPKAP1,ING3,PPM1B,MASP1,VPS13C,QRICH1,BDNF-AS,PTPRE,PTPRG,FAM184A,RFX3,RGS12,RNASEL,KLHDC8A,CCDC25,S100B,ATXN7,CASC3,HSPA4L,SGK1,SH3BGR,KIF16B,CHD9,FBXO11,FNDC3A,NLGN1,DHX30,SLC11A1,SNRPN,MYO16,PDZD2,KDM3A,SP4,ZC3H13,ATP10B,CLASP2,NXT2,SYN1,ASTN2,ADGRL3,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,TPM1,TRO,TSC1,SGK3,SLC35A4,BCL2L13,CCDC14,P2RY12,ZNF781,CLDND1,PCDH20,MICU3,MKRN3,TMEM198,ZNF184,DHX33,CIAPIN1,MDH1B,KCNAB1,PCBP4,WNK3,PDSS2,KAT6A,KLHDC1,CPNE4,JPH3" MicroRNA hsa-miR-550*:mirSVR_lowEffct hsa-miR-550*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.39E-71 3.57E-67 4.01E-70 3.69E-69 200 1244 "NCKAP5,GALNT16,PLEKHH1,AP2A2,SEMA6A,ALCAM,AMPH,CDC14B,TMEFF1,ARNTL,STK33,NUMB,ATP1B3,SLC2A11,ADAM23,LINC00847,BBS2,MPDZ,HCN2,BMP7,DST,SYNJ1,ARHGEF7,CASTOR3,CACNA1G,KALRN,PTBP2,CAST,METTL6,SYNGR3,DGKI,LRRFIP1,LOC730101,MAGI1,CCPG1,SRSF11,CHRNA4,EPS15L1,QKI,MAP4K4,FAM149A,COX4I1,AHCTF1,FAM171B,RBM39,GDA,TRIM69,CS,VAC14-AS1,PHACTR3,PUM1,DNAL1,ARMCX4,TIAM2,GUCD1,CHRDL1,DLX1,DMD,USP3,CPEB2,ECM2,FARSB,EBF1,EDNRB,CNNM1,EIF5,IRAK4,RGS17,TUBD1,STX2,SRRM1,ZNF549,ARMCX1,CLVS1,ST3GAL6,PRMT5,FER,GTF2IRD2,FGF12,FGF13,C2orf88,EFCAB2,WDR83,APOPT1,FAM49B,NSG1,ABLIM2,GABRG1,GAD1,GALC,TMEM8B,KIAA1841,MSTN,COPS8,DBF4,CBX1,ADGRA3,GRIA2,GRM8,CIT,GUCY1A1,GUCY1B1,IRAK3,SHISA6,IDH3A,IL6ST,ITGAM,LAMP2,LIFR,CLEC18A,MEIS2,POC1B,AFF1,ZC3H12B,NF1,ALDH1L2,NOVA1,NTRK2,IGSF11,OXTR,PCDH9,PCSK1,PCSK5,FAM98B,ZDHHC8,FAM216A,JAKMIP1,STRN3,IRX1,PPM1B,RASGEF1B,PRKCB,PTN,TMEM260,PTX3,CEP97,ACSS3,FAT4,GTDC1,NUDT11,ZFHX4,CCDC82,CARF,GSTCD,RORB,CCDC102B,SEMA6D,SGK1,SH3GL3,ASAP3,FBXO11,SEC31A,SLC12A2,ZKSCAN3,LMBRD1,FAM126B,ATP10B,PBLD,SSTR2,NKAIN2,ELOVL4,KANK1,SULF2,SYNE2,TAF9,TCF4,KIAA0930,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,SLC44A1,THRA,TLR4,TPM1,NPL,ZNF346,EIF4ENIF1,FLRT2,PLEKHH2,WRN,CFAP298,PCDH20,MICU3,LYPD6,CELF4,REEP1,PRTFDC1,RNF103,HPS4,FIP1L1,FBXO36,JMJD1C,RNF170,NETO1" MicroRNA hsa-miR-1227:mirSVR_lowEffct hsa-miR-1227:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.56E-71 3.67E-67 4.11E-70 3.79E-69 218 1467 "RALGAPA1,KDM5D,FMNL2,ADD1,AP2A2,OSBPL1A,TAOK1,BBOX1,AMPD3,LRCH2,PHF12,APBB2,APLP1,BCAS1,USP37,SFMBT2,MARCH3,MARK4,ATP2A2,SYNJ1,SYNJ2,GYG2,SGCE,CA8,CACNB4,ISPD,MTMR7,SEPT7,CDH2,CFL2,SRSF11,MS4A7,CPNE6,NRXN3,MYL6B,C4orf33,SRP14-AS1,AKAP6,SUMF2,MAGED1,MYRIP,CPS1,CRHBP,CRMP1,TRIM69,ABCG1,CSF2RA,CSNK1E,OSBPL3,PDE4DIP,CNTNAP2,RIMS2,PPP6R2,RUBCN,CCDC144A,BOC,CENPL,TBC1D5,ARMCX4,SPATA2,ZNF804A,ZBTB24,B3GAT3,SPOCK3,ZNF582-AS1,EXOG,SLC29A4,NR1D2,DPH1,DTNA,DTNB,ECM2,DNAJB6,ABCC5,EDNRA,HIPK3,TMTC1,FAM13A,AASS,ENPP6,ADGRV1,HSPA12B,FKTN,ZNF589,FGF13,BAIAP2,PRKAG2,POLK,EFCAB2,NBEA,HVCN1,APOPT1,CGREF1,IP6K3,SRRM4,GFER,GGT7,GLYR1,TNRC6A,CBX1,PRUNE2,MCHR1,TMEM121B,ATE1,KAT7,ADAMTS6,SLC2A6,UBE2QL1,FRMD3,VSIG4,CPT1C,SHISA6,C2orf72,RBPJ,INPP5B,KLHL23,GATD1,MAT2A,MEIS1,MID1,POC1B,XRRA1,PTOV1,LYRM9,HNRNPM,OPA1,CDK18,GPR85,XRN1,PKM,NLE1,SLC25A23,PRIMPOL,SCHIP1,PCDHB17P,PRKAB2,CEP41,GRAMD1C,MASP1,RELN,VPS13C,DEF8,CCDC40,FAT4,SUSD4,OXR1,RASGRF2,DCUN1D2,SETD5,ROBO1,MRAP2,ATP8B4,GLDN,RPS6KA2,PTGR2,HSD11B1L,ATXN7,PEAR1,FOXRED1,FBXO11,FNDC3A,FHOD3,SEC31A,LIMS2,ZNF430,KBTBD4,CDK5RAP2,SNRPN,PDZD2,UHRF1BP1L,SPTAN1,ZNF621,ATP10B,TROVE2,POGZ,NKAIN2,STAU1,NECAB1,PLCB1,ALG1,ATMIN,DMXL2,SYNE1,PCDHB9,ARHGAP9,FAM200B,ITGB3BP,MTMR14,ACTR6,TLR4,KAT6B,WBP2,ZNF346,TRO,STXBP4,PPIL6,TSC1,SSBP2,SGK3,ZNF610,RPL7L1,EIF4ENIF1,UGT8,WIPF1,RICTOR,XRCC4,ZNF711,ZNF708,ZNF24,MKRN3,TMEM237,HPS4,SEMA3B,PPP1R3F,EPM2A,RNF146,PRRT4,SENP7" MicroRNA hsa-miR-520d-3p:mirSVR_highEffct hsa-miR-520d-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.98E-71 3.91E-67 4.38E-70 4.03E-69 210 1367 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,STK33,STX16,DPY19L3,ATP6V1G2,BACH1,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,CA12,CALB2,THSD7A,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,IQCK,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,ZNF804A,MYEF2,ZC3H11A,GRIN3A,HS3ST2,DMTF1,DTNA,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,DENND4A,DNAJC27,CORO2B,MED12L,POLK,SUCO,MSANTD4,FYB1,MEGF11,HRASLS5,IGSF5,GGTA1P,COPS8,HPGDS,TNRC6A,GLUL,ZNF638,MAP7D2,GPR12,GPR34,PCLO,KAT7,ARHGAP36,SMAP1,MSL1,IDH3B,KCNJ16,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,LAYN,MYO9A,NACA,NELL2,NF1,NRCAM,OCRL,OGG1,OPA1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,CEP97,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,MCMBP,RPS20,SHC4,FBXO11,FNDC3A,WDR37,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,SYNE2,DNAJC9,PLCB1,CAMTA1,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,VLDLR,VSNL1,LYPD6,LAMP5,CADM2,LINC02210,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-106a*:mirSVR_highEffct hsa-miR-106a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.74E-71 5.45E-67 6.09E-70 5.61E-69 184 1059 "RALGAPA1,CLK4,CCDC85A,ADGRF5,SPARCL1,AMT,CDC42BPA,LRCH2,BCAS1,ZFYVE28,CADPS,NCOA1,NUMB,SLC4A4,EIF4G3,ZNF583,DPY19L3,ADAM23,ADGRB3,MPDZ,SEC11C,ZNF599,PROM1,BMP7,DST,FUBP1,JAZF1,IL33,PTBP2,CAST,LDB2,CDH2,LRRFIP1,MAGI1,B4GALT6,RAB28,CLCN3,QKI,IQCK,AKAP6,SLC4A8,ABI3BP,LRRC3B,ARHGEF10,SIPA1L1,PDE4DIP,KIAA0040,GREB1,HDAC9,DGKB,DAPK1,SPOCK3,SEC16A,CPEB2,DTNB,ABCC5,GOLT1B,E2F6,HIPK3,FAM13A,PHF20L1,SUGP2,PLEKHA1,C8orf37,SRRM1,EYA1,TMEM132C,FCGR3A,SEC24B,BAIAP2,MEX3B,SLC37A3,TMEM107,FAM49B,GABBR1,GALNT15,DISC1,ACSS1,ARFIP1,GGT7,PPARGC1A,TXNL4A,COPS8,MSL3,ZNF638,GRIA2,GRIN2D,RNF165,MSL1,IDH3A,KCNN3,IPO5,STXBP5,HECTD2,MBNL1,MEF2C,MEIS1,MMP16,ZNF680,ADAM22,P2RY13,NEFM,NFYA,NRCAM,OCRL,CLDN11,CNTN3,PDE3A,ZNF655,PURG,ING3,EPB41L4B,SH3KBP1,DIRAS2,CNTLN,PEX2,ZSCAN2,FAT4,ERI2,GTDC1,RFX2,RGS12,SLC25A36,GSTCD,RORB,CCDC102B,RPL15,BAALC,LRRK2,CLIP1,ZNF568,CSRNP3,LRFN5,PEAR1,SH3GL3,FERMT1,KIF16B,CPEB3,FNDC3A,WDR37,PREX2,SEPHS1,CCDC88A,RCOR3,LIMCH1,SNAP25,SNCA,CMTR2,SNRPN,FAM219A,CDK19,TSPYL2,ATP10B,CLSTN2,NXT2,SEPT8,RGL1,DIP2A,TACR1,PJA1,CAMTA1,ADGRL3,AGTPBP1,SYNE1,OBSL1,PCDHB3,TEK,AP4E1,SLC44A1,R3HDM1,PDSS1,RPL7L1,ZNF709,VSNL1,ZNF781,TCEAL7,FSTL5,EML6,MFF,CADM2,MDH1B,NAV3,RTN4,NETO1" MicroRNA hsa-miR-557:mirSVR_highEffct hsa-miR-557:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-70 6.36E-67 7.11E-70 6.54E-69 177 981 "KCNH8,ABHD6,ACTN1,PWWP2A,ADRA1D,OLMALINC,ZNF608,HACE1,ALCAM,ABCD2,UNC79,AMPH,ZFAT,ANK2,NCOA1,ATP2B2,DOCK11,TTLL9,BACH1,BCL7A,SYNJ1,JAZF1,PRC1,CCK,DGKI,LRBA,CDH2,ZMYM4,LOC730101,MAGI1,CHGB,B4GALT6,RAB28,CLTC,IQCK,ARMC8,AKAP6,SLC4A8,MYRIP,SEC31B,ARHGEF10,PLXNA4,DZIP3,ERC2,PHF14,RIMS2,HDAC9,RIPOR2,LONRF1,KIAA0586,GIT2,ELMSAN1,KIAA0753,LYPD1,RHOBTB1,SPOCK3,MAMLD1,DNAJB6,EDIL3,WDPCP,ANKRD46,CNNM1,KLHL5,PHF20L1,KMT5B,EIF4G2,EIF5,RGS17,PCOLCE2,DCTN4,EPHB1,DLC1,MED12L,FHL1,FLT1,C2orf88,POMT1,SMC2,CAMKK2,KHDRBS3,NSG1,GABRA3,C15orf41,GATM,TUBA8,AHDC1,PCDH17,DHRS4,PCLO,BACH2,HMGCL,HNMT,MSL1,IDH3A,ZIC5,SLC35G1,KCND2,STXBP5,TTYH2,LAMP2,HECTD2,MAP4,MARK3,MATN2,MATN3,MEIS1,MIA2,COL28A1,ADAM22,NELL2,NPTX2,NTRK2,NTRK3,OXTR,PAX6,PCDH9,ING3,MAPK9,HYDIN,CNTLN,TMEM260,PTPRD,PTPRO,STRC,USP47,REV3L,PCMTD2,FBXW7,STK32B,LRRK2,SEMA6D,ATXN7,TNFRSF19,COPZ1,FERMT1,CHD9,PPP4R3A,DHX30,KANSL3,ATF7IP,TET1,DMRTC1,RCOR3,LMBRD1,SP4,HECW1,NXT2,SEPT8,ZC3H4,ADAMTS17,ANKRD12,FAM208A,AGTPBP1,DMXL2,ZFP90,SYNE1,FRYL,TEK,ITGB3BP,RGMB,PRR18,FAM155A,UBE3A,VIPR2,XRCC4,CFAP298,ZIC1,ZNF540,ZNF154,SIGLEC10,PDSS2,AMN1,UBE3B,FBXO36,RNF170,SPATA13,SENP7" MicroRNA hsa-miR-513a-5p:mirSVR_highEffct hsa-miR-513a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-70 7.79E-67 8.69E-70 8.00E-69 174 949 "CLK4,SLC24A4,RTL9,AK2,AMPD3,LRCH2,LCORL,PHF12,SFMBT2,MARCH3,ATP6V1G2,SEC11C,ZNF599,SYNJ1,ARHGEF7,CACNA1B,KALRN,CAST,RUNX1T1,METTL6,USP2,CD86,ENTPD6,ZMYM4,LOC730101,NDST3,FAM189A2,QKI,IQCK,ARMC8,NCOR1,TRIM69,ARHGEF10,VAC14-AS1,CTH,PPP6R2,KIAA0586,DGKB,JAKMIP2,RHOBTB1,WDR20,EXOG,DPYSL2,RCAN1,ARRDC4,DTNA,FAM78B,MAMLD1,EDIL3,RASGRP1,EGFR,DCTN4,EPB41L2,DNAJC27,TLR7,ADGRV1,EYA1,TMEM132C,MED12L,OLFM1,FGF14,MEX3B,IP6K2,IQCG,DCTN2,PDLIM5,USP21,SARAF,AP4B1,ZNF44,CHL1,IQGAP2,ERAP1,ZNF559,DISC1,NEU3,SULT1C4,PPARGC1A,MALT1,DHRS4,ZNF638,GRB10,C1QL4,FAM19A2,ZBTB49,MAP4K5,C2orf72,IL6ST,INPP5B,KCND2,MAP2,MARK1,AQP11,MID1,ZNF680,IGSF11,PCDH9,ABCB1,ZNF655,SNX10,XRN1,PDZRN4,SEPT4,MAPK7,MAPK9,MASP1,WBP1L,SNRK,USP47,FAM184A,KHDRBS2,RFX3,RGS3,RGS12,CCDC82,ALG9,RORB,NEK11,BAALC,LRRK2,NCBP3,FAM192A,PRCD,SUPT20H,SH3GL3,SLC6A11,KBTBD4,NAPB,SNAP25,ZNF415,SNRPN,MYCBP2,MCF2L2,CLSTN2,SYN2,SYT1,COBL,MTCL1,DNMBP,ADGRL3,TBCEL,KLHL4,TRIM2,SYNE1,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,FAM124A,C9orf85,ZNF346,STXBP4,DCBLD1,SSBP2,UBE2H,RICTOR,XPO1,LYPD6,ZNF189,DPYSL5,MAP3K12,EMSY,RNF103,MPPE1,PDSS2,JMJD1C,TRAM2-AS1,RNF146,PRRT4" MicroRNA hsa-miR-135b*:mirSVR_lowEffct hsa-miR-135b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.56E-70 8.73E-67 9.73E-70 8.96E-69 186 1085 "ABCF1,SYS1,TMEM132B,GALNT16,ADCY6,RNF157,ADD1,ADORA1,PTCHD1,SORCS2,SEMA6A,MARCH4,UNC79,AMPD3,AMT,ZFAT,LRCH2,APLP1,UPRT,APOC1,CADPS,DYNLL1,TMEM108,ATP2B2,MPDZ,NRP2,CFLAR,BMP7,ARHGEF7,JAZF1,CACNA1A,CAPN3,KYAT1,SEPT7,EVI5L,CDO1,CACNA2D2,SRSF11,CHN1,RAB33A,RAB28,TPP1,STOML1,CNN3,ARMC8,RTTN,FAM171B,CRY2,SNCAIP,RGS6,SEC24C,CSNK1G3,CNTNAP2,KIAA0408,DCAF8,HDAC4,EARS2,ZNF337,ARMCX4,JAKMIP2,KLHL3,SNAP91,SGSM2,ACOT8,DRP2,DTNA,ECM2,PHC2,HIPK3,KLHL5,PHF20L1,EGFR,MBNL2,RASA4,C8orf37,RABEPK,SRRM1,CEP85L,ETV1,RASL12,ABCA8,FCGRT,STRADA,ZNF589,GTF2IRD2,POLR1B,FGF11,AGAP2,JKAMP,CAMKK2,ABLIM2,GABRB3,DISC1,NEU3,TUBGCP4,GFER,FREM1,TOX3,KCNMB4,GNG4,PRUNE2,CNTRL,GRM2,PRDM5,GSTT2,SLC2A6,PADI2,ELOVL5,NEGR1,LRRC75A,LRRCC1,IL6R,STMN1,HECTD2,GPR155,MARK3,MATN2,MBNL1,MN1,CCDC13,IGSF11,PFKFB3,NLGN3,PIK3C2A,PLCD1,LRP12,MAPK4,MAPK9,GRAMD1C,PIGG,CNTLN,TMEM260,PTPRB,CASTOR1,USP47,GTDC1,ZDHHC4,SUGCT,CARF,ROBO2,ADAL,TCP11L1,ABCA11P,ST6GALNAC6,NCBP3,TRAPPC13,ATXN2,SCP2,TNFRSF19,MRAS,TRA2B,KIF21A,DHX30,ATF7IP,ANKRD36,SNCA,BDP1,SPART,TROVE2,ITPRID2,ZNF302,ZC4H2,SEPT8,RHBDL3,VPS13A,CLASP1,OBSL1,FRYL,CYB561A3,SIRT1,THRA,ERCC6L2,RGMB,SYNPO2,UBTF,ZNF23,ZBTB38,FSTL5,ZFAND5,PRTFDC1,DNALI1,SLC38A1,PRDM8,PRDM10,KAT6A,ST8SIA2" MicroRNA hsa-miR-532-5p:mirSVR_highEffct hsa-miR-532-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.59E-70 8.91E-67 9.92E-70 9.14E-69 181 1028 "ACADM,C3orf14,XKR4,KLHL32,PWWP2A,KIAA1211,ADRA1B,PCDH19,AK2,ABCD2,LRCH2,BCAS1,CDC14B,BACH1,KSR1,DST,SYNJ1,ARHGEF7,CAMK2G,CAPN3,CAST,KRIT1,ZMYM4,CDO1,DLGAP1,QKI,ARMC8,SUMF2,RTTN,CLOCK,HAPLN1,SLITRK5,ARHGAP24,TBC1D5,PLPPR4,USP3,DPP6,PDCD6IP,DTNB,RASGRP1,KMT5B,AASS,TUBD1,ZNF549,DNAJC27,F5,F8,RACK1,SEC24B,FGF11,SUCO,SEC23B,RGPD5,NBEA,PDLIM5,ATP2C1,NSG1,CHL1,IGSF5,MSTN,ADAM28,COPS8,DBF4,ZNF638,FUT10,STON1,GRIA2,RNF165,ZBTB49,FAM222A,FRMD5,C9orf129,NEGR1,NKD1,RBPJ,IL6ST,IPO5,KTN1,HECTD2,SMAD1,MAP2,MAP4,LRP1B,MEIS1,SRSF12,POC1B,XRRA1,ADAM22,ZNF92,P2RY13,NCF2,NDP,NEK1,NF1,NOVA1,SLC11A2,NRCAM,OCRL,P2RY1,GPR137C,PCDH9,PCSK1,PRTG,PFKFB2,OLA1,NALCN,PIK3C2A,CCSER2,GPSM2,PURG,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,MINDY2,PRKACB,VPS13C,CNTLN,TMEM260,PTPRB,OXR1,RADX,GTDC1,NUDT11,PBRM1,TMLHE,GSTCD,ROBO1,ELP2,CCDC102B,SPIN3,ZC3H14,ABCA11P,SH3BGR,CPEB3,CHD9,SYBU,SEC31A,EPN2,SLC8A1,CCDC88A,BTBD7,CXXC4,RCOR3,TTC17,PDZD2,KDM4C,ZNF423,ZC3H13,CDK19,TROVE2,ELOVL4,SEPT8,KLHL7,JMJD6,PCDHB10,NSD1,PUM2,FRYL,TIAM1,BHLHB9,SYNPO2,PDSS1,RPL7L1,GUSBP1,XPO1,PCDH20,LYPD6,FSTL5,SPIRE1,SMARCAD1,UPF3A,SLC30A4,PRDM10,FAM47E,WNK3,PDSS2,RGS7BP,FZD3,DOCK8" MicroRNA hsa-miR-192*:mirSVR_highEffct hsa-miR-192*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-70 8.99E-67 1.00E-69 9.20E-69 171 917 "ACADM,NDRG3,KLHL32,ADD2,BRAP,ZNF608,CC2D2A,BBOX1,GPRASP2,PKP4,RASL11B,ATP6V1G2,MIR9-3HG,SYNJ1,SGCE,SLC25A14,LRBA,SEPT7,CDH2,LARGE1,TIGD7,RCBTB2,CHN2,PLEKHB1,TAOK2,AKAP6,CNRIP1,CLOCK,RBM39,OSBPL3,VCAN,PDE4DIP,DZIP3,DCAF4,HDAC9,ARHGAP32,MATR3,TMEM170A,DAPK1,DDX46,DMD,DNM1,ECM2,E2F6,EDN3,FRY,OPTN,YAF2,AASS,RABEPK,CLVS1,PTK2B,SCML2,CEP78,GORAB,FER,SUCO,SYNCRIP,NBEA,STAU2,OGA,FYB1,GALNT15,GABRG2,TRAF3IP2,ERAP1,MTHFD2,ZNF559,NEU3,MMADHC,MALT1,CBX1,GNG4,GPD2,STMN2,KAT7,GSTT2,DDX19B,MIER3,VSIG4,SMAP1,SCIN,TTYH2,LAMP2,MAP4,LRP1B,ZNF92,NEFM,NF1,NFE2L2,TREM2,ZNF655,SEPT4,KANSL1,EPDR1,GDPD1,CNNM2,SNRK,CNTLN,TMEM260,PTPN13,ZNF615,ZNF493,MORC4,GTDC1,UBR7,RIC8B,CARF,STK32B,NCBP3,CCDC112,TRAPPC13,ATXN7,LRFN5,SCP2,NLGN1,NUBPL,FAM81A,FAM214B,ZNF430,SLC6A11,NAPB,ATF7IP,TET1,RCOR3,ANKRD36,PDZD2,ZSWIM8,MYCBP2,ZNF423,SPART,TROVE2,ITPRID2,NKAIN2,NXT2,ADHFE1,KANK1,SYT1,CAMTA1,TCEA1,SATB2,RPGRIP1L,SYNE1,KHDC1,SLC44A1,BHLHB9,NPL,ANKRD20A2,CLHC1,UBE3A,CCDC14,TBC1D15,WIPF1,GUSBP1,ZNF708,ZNF138,ZBTB38,SPIRE1,UPF3A,ADAMTS9,NAV3,KCNAB1,EPM2A,MRPL47,PHTF2,FBXO36,CASC15,MSRB3,DPF3,RNF146,ZNF30" MicroRNA hsa-miR-1229:mirSVR_lowEffct hsa-miR-1229:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.23E-70 1.25E-66 1.38E-69 1.28E-68 222 1528 "ABR,SYS1,KDM5D,NDRG3,PSMG3-AS1,ADD2,ADORA2A,SYT13,ZFAT,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APBB2,PHYHD1,LGR5,CDK10,CASK,CDK13,TMEM108,ATP2B2,RNF182,N4BP2L1,ATP6V0A1,ADAM23,ADAM15,BBS2,MPDZ,BCL7A,CFLAR,AP1M1,CA12,VXN,CAST,CBLN1,METTL6,CCNH,MTMR7,SLC16A4,CBFA2T2,DGKI,LOC730101,CRLF1,CACNA2D2,CHRNA4,NRXN3,PPT2,C4orf33,SULT4A1,MAP4K4,CNN3,AKAP7,COL9A1,SLC4A8,CDC42BPB,CREM,RBM39,GDA,CSF2RA,ARHGEF10,VCAN,PDE4DIP,FAM169A,GREB1,DCAF4,CCDC144A,CYBB,ARHGAP24,ZNF337,RASSF2,KIAA0586,DGKG,HEPH,SNAP91,SGSM2,FAM107B,KLHL5,MRNIP,EMX2,PTK2B,TUBB3,CORO2B,ZSCAN30,FGF12,FGFR1,AMOTL2,PCYOX1,SYNCRIP,SEMA4D,SYT3,PDLIM5,ZNF605,SARAF,NEURL4,MEGF10,ZNF274,SEPT9,CPLX2,KIAA1841,GCNT2,NTNG2,TXNL4A,ZNF638,DCLK2,GPT2,FUT10,GPR37,GRIA2,PLCD4,GRIN2C,ATE1,LINGO1,FAM222A,MAN1B1,SYNPO,HNF4G,ZDHHC15,ZNF546,C2orf72,SCIN,IL6R,ITGA7,SLC35G1,KIT,PIK3AP1,MAN2A2,ZFYVE27,MAP6,MAPT,CHST6,ZNF92,NF1,NTRK2,OPA1,PDCD2,PDE1C,PDE4D,PFKFB4,TMIE,PCDH18,SDK2,SH3KBP1,PPP2R5E,NKAIN4,MAPK9,DIRAS2,BCAS3,NCR3LG1,PTPN13,PTPRB,PTPRG,C1orf109,NKAIN1,SLC25A48,SH3TC2,RASGRF2,RFX3,PRIMA1,RNASEL,LGI2,ARMC5,CARF,KIRREL1,YY1AP1,ELP2,GLDN,ADAL,KCNIP3,CLIP1,RTN1,FAM192A,ATXN7,MRAS,AMBRA1,FBXO11,ST6GAL1,SLA,MBD5,SNRPN,ZSWIM8,KDM4C,UNC5B,SPART,NFASC,ELOVL4,CEP68,DIP2A,STXBP1,RHBDL3,SYP,CAMTA1,PDLIM2,SYNE1,OBSL1,PUM2,ARHGAP9,CHST8,ZNF106,FAM124A,CDK20,SYNPO2,TRIO,KCNE5,TTTY15,WIPF1,ZNF24,TRIM9,ZNF74,NDRG4,LYPD6,POLR3H,AMZ1,PCBP1-AS1,MEIS3,RNF103,WNK3,FZD3,SMIM8,HNRNPA3,JMJD1C,TIGD6,TTC7A,NETO2,SOCS4" MicroRNA hsa-miR-4316:mirSVR_lowEffct hsa-miR-4316:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-70 1.46E-66 1.62E-69 1.49E-68 210 1377 "ASIC1,GALNT16,ADCY6,ADD1,ADD2,BRAP,ADORA2A,KIAA1211,ESYT2,ADRB2,HACE1,CC2D2A,AK2,FGD2,MAP4K3,PPFIA4,CPNE5,CDK10,PPP4R4,CDK13,DNAH17,RNF182,BCHE,CFLAR,DST,ARHGEF7,GPC2,BAIAP3,CFAP410,NFS1,CLDN10,ARHGEF1,CBFA2T2,LARGE1,CFL2,PLAA,CLTC,ABCG2,ARMC8,CABP1,ANKRD35,CNRIP1,CSF1,CSF1R,VCAN,PDE4DIP,RASGEF1C,DZIP3,FAM131B,CYBB,ARHGAP24,LONRF1,TMEM170A,DAPK1,DAPK3,DGCR5,SPOCK3,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DNM1,DPH1,ACOT8,DRP2,TOM1,DUSP9,MAMLD1,EBF1,EDN1,OPTN,STARD3NL,EIF1,EPB41L2,EPHB1,ABCA8,TUBB3,CORO2B,FCGRT,FGF12,AMOTL2,SCARA3,SEMA4D,PSD2,PRELID3A,CGREF1,AP4B1,GABBR1,GABRB3,FAM120B,LRRC37A6P,GCK,SULT1C4,MMADHC,ZNF782,WDFY3-AS2,ADAMTS13,GRM2,FAM107A,ATXN2L,TNFAIP8L3,ARHGAP36,LRRC75A,SHISA6,KIAA1755,SLC35G1,TTYH2,LIMS1,MAN2A2,LYPLAL1,AQP11,MBP,MEIS2,LYRM9,RTL5,NEFM,CNOT4,NUCB2,OPA1,LOC100128398,CLDN11,CDK18,SLC10A4,XRN1,PKM,FA2H,SH3KBP1,POU6F1,PPP1R1A,MAPK4,MASP1,CNTLN,NCR3LG1,ZIK1,PTPRB,PTPRO,CEP97,RAD51D,NWD1,RASGRF1,KHDRBS2,DPF2,MORC4,PRIMA1,KCTD17,ATP8B4,TCP11L1,HSD11B1L,ATAT1,CLIP1,SATB1,PEAR1,SEC14L1,STUM,WDR37,SLA,SLC4A3,SLC9A5,KBTBD4,ATF7IP,SMARCD3,SNCA,BDP1,ZSWIM8,MYCBP2,IQSEC2,TROVE2,ERBIN,SEPT8,DIP2A,SEPT3,NSFL1C,SLC37A2,TACC1,CAMTA1,TAL1,PDLIM2,ADGRL3,KLHL4,USP22,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZMAT3,SLC44A1,HEY1,TK2,ERCC6L2,TMPO,KAT6B,TNS1,PIK3R5,C9orf85,RGMB,SMUG1,TSC1,ATP6V0E2,REEP1,TMEM237,MEIS3,STOX2,FIP1L1,UBE3B,KLHDC1,ST8SIA2" MicroRNA hsa-miR-4296:mirSVR_lowEffct hsa-miR-4296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.77E-70 1.55E-66 1.72E-69 1.58E-68 209 1365 "RALGAPA1,EMILIN3,FMNL2,GALNT16,ADORA1,ADORA2A,KCTD16,WDR35,PCDH10,LRFN1,ZFAT,SUGT1P4-STRA6LP-CCDC180,SEMA4G,MADD,DYNLL1,TTLL9,ADGRB2,BTK,IL33,KALRN,RHBDL1,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,NRXN3,CLTC,QKI,CNTFR,IQCK,SMARCAL1,ZFP28,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,GREB1,ARHGEF4,BOC,MYADM,ZNF337,IP6K1,DGCR5,HEPH,TIAM2,FBXL5,KIAA0753,CD99L2,ARRDC4,TOM1,EDN1,EDNRB,YAF2,PHF20L1,APH1A,EBI3,EGFR,IRAK4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,IP6K2,FLT1,NOP56,CINP,CELF1,NEURL4,ALDH1L1,TUBGCP4,TTBK1,ZNF638,MAP7D2,POLL,PRUNE2,STON1,MCHR1,RNF165,FAM107A,ADAMTS6,HMGCL,HNF4G,DHX35,CELF5,MYLK2,LRRC25,INSM1,C2CD4C,SLC35G1,KCNH2,LIFR,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,MYO5A,MYO7A,CLDN11,OXTR,P2RY1,CDK18,NALCN,FAM218A,CCSER2,PLCB2,MAPKAP1,FA2H,POLR2F,PPARA,PRODH,MASP1,RELN,SAMD9,WDR25,ZSCAN2,NWD1,RASGRF1,GTDC1,CARF,ROBO2,CCDC25,SNX22,SGSM1,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,KCNIP3,RYR3,LRFN5,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,SHMT2,LIMS2,KANSL3,PKNOX2,SLC6A8,LGI3,KIF13A,SNRPN,FAM219A,IQSEC2,CLSTN2,ZC4H2,SSPO,SEPT3,JMJD6,ARC,COBL,TACC1,MLST8,IQCE,CLASP1,SZT2,SYNE1,CYB561A3,GALNT17,ERCC6L2,RIMBP2,CABIN1,WBP2,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,VLDLR,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,NDRG4,ZBTB38,AMZ1,DPYSL5,PCBP1-AS1,DNALI1,PRDM10,RGS7BP,TMEM63C,RNF170,JPH3" MicroRNA hsa-miR-1263:mirSVR_lowEffct hsa-miR-1263:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-70 1.75E-66 1.94E-69 1.78E-68 170 910 "ACADM,GALNT16,ADCY6,PWWP2A,BEND6,TAOK1,USP35,ARHGAP20,ALK,LRCH2,UPRT,TNRC6C,TMEFF1,RIPK1,DOCK11,ADAM23,BCL7A,BID,CACNA1B,CACNB4,HIP1R,CD38,ARHGEF2,CDH2,NUMBL,COPB2,SRSF11,ASIC3,ARHGAP22,CLCN3,MYL6B,COL9A1,ZNF521,CS,SEC24C,SUSD5,FAM169A,KIAA0040,PLCXD3,DCAF4,ARHGAP24,YTHDC1,KIAA0319,PLPPR4,SGSM2,DNM1,HS3ST2,DOCK2,ACOT8,E2F6,EDNRA,RASGRP1,YAF2,SUGP2,MBNL2,GPHN,CDKL3,CORO2B,DLC1,RACK1,CEP78,SEC24B,FGF12,ATP13A4,NOP56,NELFCD,EFCAB2,FAM49B,CELF1,MEGF10,GAD1,IP6K3,ACSS1,ALDH1L1,ARFIP1,ZNF496,BTN2A1,RASSF8,RBPJ,IL6ST,IL12A,SLC35G1,KCNN1,STXBP5,HECTD2,KCTD6,MID1,COL28A1,NEFM,ALDH1L2,NFYA,NTRK2,PCDH9,PCSK5,ENPP2,PDPK1,GPR85,ZNF655,FAM216A,ANKRD16,STRN3,RETREG2,EPB41L4B,SH3KBP1,FSD1,PPP2R2C,PRKACB,PRKCB,MAPK10,PRPH,WBP1L,PTN,PTPRG,PTPRN,PTPRO,FAM184A,NWD1,RAP1GDS1,ENOX1,MSANTD2,RFX3,ZFHX4,CARF,PNMA8A,ROBO2,NEK11,EPHA10,GLDN,HUNK,RTN1,SCN8A,HES6,PEAR1,SUPT20H,NUBPL,PPP4R3A,EPN2,KANSL3,ANKRD36,SNRPN,BDP1,TROVE2,NEK4,PRRC2C,SYP,FBXW11,TPCN2,TRIM2,RPGRIP1L,NAT16,DOCK9,USP32P1,SIK3,DICER1,ZFPM2,ZMAT3,TLR4,SLC35A4,LAT2,PCDH20,ZNF708,TRIM9,FTSJ1,EMSY,STOX2,ADAMTS9,GAL3ST3,MPPE1,FAM219B,JMJD1C" MicroRNA hsa-miR-643:mirSVR_highEffct hsa-miR-643:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.63E-70 2.03E-66 2.25E-69 2.07E-68 183 1056 "NCKAP5,HECW2,RTL9,OSBPL1A,OSBPL8,SPARCL1,FAM135A,ALK,LCORL,ARNTL,RNF182,DPY19L3,TTLL9,BACH1,CFLAR,DST,IL33,CA8,CACNA1B,DDR1,KALRN,CAST,SPAG9,CD86,ZBED1,CDH2,KCNAB3,CLGN,NUMBL,RAB33A,CLCN3,QKI,CNR1,SLC4A8,TOGARAM2,CNRIP1,CLOCK,RBM39,GDA,CSF2RA,ARHGEF10,PHACTR3,DZIP3,PHF14,GAPVD1,TCAF1,ZFYVE16,LONRF1,DGKB,ZNF804A,DDX46,SV2B,USP3,CPEB2,DTNB,ECM2,E2F5,HIPK3,RASGRP1,KLHL5,YAF2,PHF20L1,MBNL2,IRAK4,CDKL3,F5,SEC24B,SLC9B2,GTF2IRD2,SUCO,C2orf88,WDR83,STAU2,C15orf41,DISC1,LRRC37A6P,MSTN,FREM1,MALT1,DBF4,SPIN1,RAB30,ZNF638,KIAA1958,GRM8,FAM19A2,ZBTB49,PSIP1,NEGR1,SMAP1,RBPJ,IL6ST,FAM69A,SLC35G1,KCND2,KCNJ16,KIT,LAMA2,PAXBP1,HECTD2,MEIS1,KCTD6,ADAM22,ZNF92,MYO9A,NUCB2,IGSF11,CHAMP1,CLDN11,PCSK5,PDE4D,NALCN,PRIMPOL,LRP12,SCHIP1,SDK2,ING3,PPM1B,DIRAS2,GDPD1,RELN,BCAS3,PTPRB,ACSS3,GTDC1,PBRM1,CCDC82,ZNF532,CARF,RORB,CCDC102B,RPE,ATP8B4,TCP11L1,ATAT1,RYR3,CCDC112,FNIP1,PPP4R3A,WDR47,CCDC88A,TET1,SMARCC2,MBD5,CABCOCO1,ZNF415,TRERF1,ZC3H13,RBM26,SST,LARP4,NEK4,RGL1,SYNE2,PLCB1,SYPL1,FAM208A,ATMIN,SATB2,ZEB1,TCF12,DOCK9,PCDHB9,FRYL,FAM200B,AP4E1,ZNF106,SLC44A1,ASXL3,TMPO,CSMD1,KAT6B,WIPF1,RICTOR,PCDH20,ZNF24,ANKS1B,SLC38A1,FIP1L1,FAM13C,CASC15,MSRB3,NETO1" MicroRNA hsa-miR-4276:mirSVR_highEffct hsa-miR-4276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.25E-70 2.38E-66 2.63E-69 2.42E-68 185 1080 "KCNH8,AS3MT,ADCY6,ADD1,ESYT2,PTCHD1,ADRA1B,HECW2,KIAA1324,OSBPL6,SEMA6A,PCDH10,PKP4,CDC14B,SPTBN4,SEC11C,CALB1,SPAG9,RUNX1T1,CBFA2T2,DGKI,LRRFIP1,L3MBTL4,SRSF11,CHGB,CHN2,B4GALT6,TPP1,CLTC,VAX2,C4orf33,HECTD1,AKAP7,SLC4A8,ABI3BP,AHCTF1,SNCAIP,VAC14-AS1,APPL1,ZSCAN23,ARHGAP24,DAPK1,PABPC5,AIF1L,ZNF804A,ALKBH8,FAM107B,DYNC1I1,FAM78B,E2F5,TSPAN5,RASGRP1,OPTN,PHF20L1,MBNL2,CALCRL,USPL1,EIF1,VPS13B,EPB41L2,IGSF6,VPS26C,ADGRV1,EYA1,ZNF461,CEP78,SLC37A3,NBEA,TMEM107,HRASLS5,GABRG2,GALC,GATM,NEU3,TUBGCP4,WASHC2A,DBF4,GPR75,GLUL,CBX1,RAB40B,FERMT2,CCDC184,STMN2,CIT,RNFT2,RASSF8,SMAP1,IDH3B,C2orf72,IL6ST,INPP5B,KIT,STXBP5,NCOA7,MARK1,MBNL1,MEST,MIA2,MID1,AFDN,CCDC13,NNAT,SLC11A2,NTRK3,PAX6,PCSK1,PDE4B,PDE4D,GPR85,PIK3C2A,FAM216A,PURG,PSAT1,FA2H,RASGEF1B,VPS13C,SNRK,WDR25,CNTLN,TMEM260,PTPRE,PTPRG,ZSCAN2,ZNF615,USP47,ZMAT4,RIC8B,NUDT11,PNMA8A,ELP2,PCMTD2,SPIN3,ZC3H14,MCMBP,ATP8B4,ZNF354C,SATB1,CPEB3,R3HDM2,NLGN1,WDR37,KANSL3,CPEB4,KDM4C,ATP10B,ZNF302,RGL1,DIP2A,NUDT10,ADAMTS17,COBL,TACC1,TACR1,MCF2L,DMXL2,RPGRIP1L,PCDHGA11,FRYL,ITGB3BP,AP4E1,AKTIP,ARL10,TMPO,NPL,METTL3,ANKRD20A2,HIRA,BCL2L13,RICTOR,XRCC4,PCDH20,MICU3,TRIM9,AGMO,DNALI1,PRDM10,ADAMTS9,MPPE1,PDSS2,MARCH8,TRAM2-AS1,TIGD6,MSRB3,FXR1" MicroRNA hsa-miR-519b-3p:PITA hsa-miR-519b-3p:PITA_TOP PITA 4.83E-70 2.70E-66 2.98E-69 2.74E-68 146 665 "USP31,SLC24A4,SRPX,CDC42BPA,LRCH2,STK33,RASL11B,KIF1A,BCL7A,NRP2,SYNJ1,USP6,DLGAP2,CFL2,FOXN3,SOCS6,QKI,RCHY1,AHCTF1,CRY2,GDA,LRIG1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,SACS,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,ERBB4,ETV1,EZH1,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,RUNDC3A,TOX3,TNRC6A,GRB10,CIT,SOX21,HAS2,MIER3,IGF1,KCND2,KCNN2,KIF5A,CAMK2N2,SFXN5,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NF1,NFIX,GPR137C,CNTN3,PFKFB3,CCSER2,EPB41L4B,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,CEP97,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,HSPA4L,FAM102A,KIF16B,CPEB3,CHD9,FAM81A,CCDC88A,CPEB4,FAM126B,SP4,TEX2,TSPYL2,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,RIMBP2,R3HDM1,UBC,FAM155A,UBE3A,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,MAP3K12,EMSY,MFF,WNK3,RGS7BP,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-519a:PITA hsa-miR-519a:PITA_TOP PITA 4.83E-70 2.70E-66 2.98E-69 2.74E-68 146 665 "USP31,SLC24A4,SRPX,CDC42BPA,LRCH2,STK33,RASL11B,KIF1A,BCL7A,NRP2,SYNJ1,USP6,DLGAP2,CFL2,FOXN3,SOCS6,QKI,RCHY1,AHCTF1,CRY2,GDA,LRIG1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,SACS,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,ERBB4,ETV1,EZH1,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,RUNDC3A,TOX3,TNRC6A,GRB10,CIT,SOX21,HAS2,MIER3,IGF1,KCND2,KCNN2,KIF5A,CAMK2N2,SFXN5,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NF1,NFIX,GPR137C,CNTN3,PFKFB3,CCSER2,EPB41L4B,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,CEP97,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,HSPA4L,FAM102A,KIF16B,CPEB3,CHD9,FAM81A,CCDC88A,CPEB4,FAM126B,SP4,TEX2,TSPYL2,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,RIMBP2,R3HDM1,UBC,FAM155A,UBE3A,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,MAP3K12,EMSY,MFF,WNK3,RGS7BP,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-519c-3p:PITA hsa-miR-519c-3p:PITA_TOP PITA 4.83E-70 2.70E-66 2.98E-69 2.74E-68 146 665 "USP31,SLC24A4,SRPX,CDC42BPA,LRCH2,STK33,RASL11B,KIF1A,BCL7A,NRP2,SYNJ1,USP6,DLGAP2,CFL2,FOXN3,SOCS6,QKI,RCHY1,AHCTF1,CRY2,GDA,LRIG1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,SACS,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,ERBB4,ETV1,EZH1,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,RUNDC3A,TOX3,TNRC6A,GRB10,CIT,SOX21,HAS2,MIER3,IGF1,KCND2,KCNN2,KIF5A,CAMK2N2,SFXN5,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NF1,NFIX,GPR137C,CNTN3,PFKFB3,CCSER2,EPB41L4B,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,CEP97,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,HSPA4L,FAM102A,KIF16B,CPEB3,CHD9,FAM81A,CCDC88A,CPEB4,FAM126B,SP4,TEX2,TSPYL2,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,RIMBP2,R3HDM1,UBC,FAM155A,UBE3A,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,MAP3K12,EMSY,MFF,WNK3,RGS7BP,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-4283:mirSVR_lowEffct hsa-miR-4283:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.84E-70 2.71E-66 2.98E-69 2.74E-68 206 1332 "ABR,ACADM,ASIC1,XKR4,GALNT16,ADORA1,ADORA2A,ADRA1D,PCDH19,KCTD16,TBC1D14,PDZD4,LRFN1,SUGT1P4-STRA6LP-CCDC180,APLP1,CDK10,ARSE,CDK13,MARCH3,STK33,INSYN2B,RNF182,ADGRB3,MYRF,DDR1,PTBP2,CAST,ARHGAP33,MAGI1,UBE2L6,SRSF11,TAOK2,NDST3,EPS15L1,RAB26,CPS1,CDC42BPB,AKAP12,GDA,OSBPL3,RIMS4,RASGEF1C,PUM1,KIF26A,SPOCK2,ARMCX4,KIAA0753,RUSC2,DMPK,ACOT8,MAMLD1,EDN3,ANKRD46,TMTC1,PHF20L1,AASS,EIF4G1,EIF5,TNK2,EIF1,EMX2,ENO2,NCALD,SPEG,RASL12,REEP2,TMEM132C,FCGRT,FGF13,AMOTL2,NOP56,AKAP3,STAMBP,CAMKK2,NSG1,TVP23A,GCK,ALDH1L1,CYP46A1,ADAM28,GGT5,TTBK1,CRCP,GNAL,GPT2,PRRC2B,STMN2,ADAMTS13,CLASRP,GSTM5,AP4S1,ATOH8,AGBL5,HSF2,IRF8,IDH3A,FAM95B1,ZNF546,TJAP1,SLC6A17,KCNN2,LINC00634,TTYH2,STMN1,MAN2A2,ZFYVE27,MARK1,ADAM11,MPP2,GIT1,N6AMT1,HS6ST3,NF1,NPTX2,SLC11A2,SETD4,PFKFB4,ZDHHC8,SNX10,PLCB2,ING3,RETREG2,POLG,PPP1R1A,MAPK9,BCAS3,TMEM104,BDNF-AS,PTPRE,CASTOR1,UBR7,LGI2,ARMC5,CYB561D1,ROBO1,BAALC,GLDN,STK32B,EMID1,KCNIP3,RTN1,ZNF568,STX1B,FOXRED1,SEC31A,DZIP1,DHX30,PKNOX2,KDM4D,SIRT2,CCDC88A,ABTB1,SMARCA4,LIMCH1,CABCOCO1,TMCC1,BDP1,SP2,IZUMO4,ERC1,LHPP,ZC4H2,DIP2A,ADHFE1,ADAMTS17,ARC,SYP,TACR1,PDLIM2,SMG6,TPCN2,SYNE1,TNS2,HIF3A,SLC44A1,THRA,TK2,ERCC6L2,TPM1,TPM2,ELP5,AMACR,UBE3A,VGF,VLDLR,RBFOX3,CLIP2,CLDND1,GUSBP1,XRCC4,LGI4,LYPD6,POLR3H,ZNF213,MEIS3,EMSY,DNALI1,STOX2,GAL3ST3,NAV3,PLD4,DOCK8,FBXO36,ADAMTS10,AP3B2,ST8SIA2" MicroRNA hsa-miR-4269:mirSVR_highEffct hsa-miR-4269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.69E-70 3.18E-66 3.50E-69 3.22E-68 152 725 "KCNH8,CLK4,CCDC85A,AP2A2,ZNF608,SMIM17,PCDH10,ALK,AMPD3,LRFN1,LRCH2,SUGT1P4-STRA6LP-CCDC180,PPFIA3,DOCK11,BCL7A,GPR146,BTK,CACNA1B,DDR1,KALRN,CAST,CLDN10,MAGI1,SRSF11,RAB33A,CLCN3,FBXO7,AKAP6,ABI3BP,CSNK1G3,PLXNA4,GAPVD1,TCAF1,ZFYVE16,DGKB,GIT2,ZC3H11A,RHOBTB1,NR1D2,DTNA,FAM78B,DNM1L,SNX29,HIPK3,KLHL5,FAM13A,PHF20L1,EIF4G1,PLEKHA1,TNK2,GPHN,ADGRV1,TAOK3,CEP78,ZNF589,SEC24B,SUCO,PRELID3A,FAM120B,C15orf41,NEU3,ALDH1L1,SPIN1,MSL3,POLL,TDRKH,PCLO,CLASRP,RASSF8,HNF4G,ZDHHC15,HSF2,IL6ST,ZNF678,LRRTM1,SLC35G1,MAN2A2,MAP2,MAT2A,MBNL1,KCTD6,NTRK3,ZNF827,PCSK1,PDCD2,CCSER2,SNX10,FAM216A,MINDY2,PPM1B,KANSL1,WBP1L,QRICH1,CNTLN,PTPRB,PTPRN,PTPRO,PPP2R3C,USP47,SH3TC2,NWD1,RASGRF2,RBBP6,KHDRBS2,DPF2,GTDC1,FIGN,PBRM1,KCNIP1,ATXN7,PRCD,SH3BGR,KIF21A,KIF16B,CHD9,ABLIM3,WDR47,ATF7IP,DOP1A,ZC4H2,SS18,ADHFE1,KANK1,SYP,C12orf76,MTCL1,DNMBP,PCDHB4,FRYL,FAM200B,SIRT1,CDH22,SLC44A1,TMEM9,PIK3R5,C9orf85,TRPS1,RPL7L1,UGT8,PCDH20,TRIM9,ZFAND5,MAP3K12,EMSY,ADAMTS9,MDH1B,NELFE,PDSS2,RGS7BP,RTN4,FAM219B,DPF3" MicroRNA hsa-miR-29c:mirSVR_highEffct hsa-miR-29c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.77E-70 3.23E-66 3.54E-69 3.26E-68 185 1082 "KCNH8,NCKAP5,KDM5D,XKR4,PTCHD1,OSBPL6,TXNDC16,ALK,AMPD3,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APC,BCAS1,TMEFF1,CDK13,STX16,ATP2A2,N4BP2L1,RIPK1,ADGRB2,PROM1,DST,NAE1,WASF1,PTBP2,RUNX1T1,C1orf52,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,GDA,CRYM,CS,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,RHOBTB1,GRIN3A,DYNC1I1,DNM1L,WDPCP,EDNRB,FEM1B,PHF20L1,EGFR,KMT5B,ELN,TUBD1,SCML2,MED12L,MEX3B,RGPD5,DCTN2,TPK1,ATP2C1,NSG1,OGA,FYB1,GABRG2,DISC1,SESN1,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,GPR37,PCLO,ADAMTS6,ZHX1,VSIG4,HMGCR,HNF4G,IGF1,SCIN,ZNF678,KIF5A,LAMA2,LIMS1,HECTD2,MAP6,MEST,MYCN,MYO9A,NEXMIF,NRCAM,ENPP2,GNG2,CCSER2,PURG,PMP22,ING3,EPB41L4B,PRKAB2,RASGEF1B,SLC26A11,GRAMD1C,VPS13C,SNRK,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,ROBO1,PCMTD2,FBXW7,SALL1,TRA2B,SGK1,SH3BGR,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,SLC12A2,NAPB,BTBD7,TET1,ZKSCAN3,MYO16,HECW1,SPTAN1,NXT2,ZSCAN29,ELOVL4,PRRC2C,VPS13A,SYP,ANKRD12,TBCEL,TCF4,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,TPM1,TSN,TUBB2A,CLHC1,UGT8,VLDLR,ZNF19,ZNF28,TRIM9,ZNF45,EML6,DPYSL5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,IFT88,FAM198A" MicroRNA hsa-miR-765:mirSVR_highEffct hsa-miR-765:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.24E-70 4.05E-66 4.44E-69 4.09E-68 182 1049 "VWA5B2,ACHE,NDRG2,MTUS1,OSBPL1A,PCDH10,PHYHD1,VAT1L,SPTBN4,LINC00173,PCDHGB4,ATP1B3,MYOM1,ADGRB3,NRP2,SYNJ2,CACNA1G,C5,DDR1,THSD7A,KALRN,RUNX1T1,LDB2,CD86,KCNAB3,DLGAP1,TIGD7,SRSF11,CHN2,PPT2,CNTFR,LETMD1,GAL3ST1,SEC31B,HINFP,CSF1,CSF1R,SUSD5,PUM1,RUBCN,IST1,DAPK1,GIT2,ELMO1,B3GAT3,CHRDL1,USP3,DTNA,FARSB,TMTC1,CELSR3,EBI3,EGFR,VPS13B,EPHB1,SRRM1,SIRPB1,EXTL2,NRN1,PTK2B,TAOK3,CEP78,OLFM1,DLL3,HRASLS5,GABRA3,C15orf41,INPP5K,CPLX1,NEU3,TUBGCP4,SRCAP,AHDC1,GGT7,TDRKH,GRIA2,SERP2,BTN2A1,FAM19A2,KAT7,LINGO1,FRMD5,ARHGAP36,VSIG4,HMGCL,SHISA6,IL6ST,INPP5B,NME9,ITGA7,GPR62,PAXBP1,MAT2A,MBD1,MEIS2,KCTD6,MMP16,ADAM22,MSR1,NRBP2,NOVA2,OGG1,PCDHGC3,CDK18,PDE4A,PFKFB3,SEPT4,LRRN3,RASGEF1B,MAPK10,HYDIN,GDPD2,ZSCAN32,NKAIN1,MARCH1,DPF2,SETD5,ALG9,GSTCD,TRAPPC13,SEMA6D,ATXN2,TNFRSF19,CASC3,MRAS,SYBU,FAM214B,ARHGEF40,CCDC88A,SMARCA4,LIMCH1,SNAP25,SNRPN,TRERF1,SP2,TEX2,CLSTN2,NXT2,SEPT3,NSFL1C,ARHGEF9,SYN2,COBL,CAMTA1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,USP32P1,GALNT17,LRRC8A,PRRT1,TRIO,RUNDC3B,RUSC1,SSBP2,HSPBP1,SLC35A4,LAT2,ZIC2,ZNF17,CELF4,ZBTB38,FTSJ1,SMARCAD1,MEIS3,RNF103,CIAPIN1,FIP1L1,UBE3B,PHTF2,CASC15,RNF170,DPF3" MicroRNA hsa-miR-769-3p:mirSVR_lowEffct hsa-miR-769-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-70 4.71E-66 5.16E-69 4.75E-68 208 1361 "ABCF1,NCKAP5,ADCY6,CCDC85A,GALNT13,ADORA1,OSBPL1A,ALCAM,AMPD2,ZFAT,SUGT1P4-STRA6LP-CCDC180,APLP1,TNRC6C,AQP6,ZBTB10,KSR1,KALRN,SPAG9,LDB2,USP6,P2RX6,CD86,MAGI1,CDO1,NRXN3,HECTD1,CNN3,ARMC8,ABI3BP,SLC35F1,CLOCK,CREM,RBM39,CLIP3,CSF2RA,GREB1,DCAF4,CCDC144A,BOC,RIPOR2,CENPL,TM9SF4,LIN54,IST1,MYEF2,SGSM2,KIF19,CHRDL1,DYNC1I1,TOM1,DUSP9,MAMLD1,ABCC5,WDPCP,EDNRB,CELSR3,FAM13A,EGFR,AASS,CERCAM,SPEG,RASL12,GMPR2,PTK2B,MAD2L2,PRKAG2,HPCAL4,SYNCRIP,FOXO3,ANKFY1,NOP56,NELFCD,CELF1,ABLIM2,FYB1,MEGF11,GABRB3,DISC1,MALT1,ZNF638,LNX1,WDFY3-AS2,PRUNE2,FUT10,LILRA2,STON1,GRM2,PRDM5,GSTM5,PACSIN2,DHX35,FAM95B1,SOWAHA,TJAP1,FAM69A,NME9,KCNB1,STMN1,PAXBP1,SYTL4,NCOA7,SMAD1,GPR155,MATN3,MEF2C,MID1,MPP2,ADAM22,ZNF92,ZNF862,DPY19L2P2,CDK18,PDE4D,PKM,NLE1,SLC25A23,MAPKAP1,LRP12,PPARA,PRKAB2,MAPK4,CNNM2,BCAS3,WDR25,PTK2,PTPRB,PTPRH,PEX2,TUG1,TMEM231,GAL3ST4,CRTAC1,TRIM68,GTDC1,KLHL11,DCUN1D2,SETD5,CARF,NEK11,ZC3H14,ATP8B4,GLDN,MEG3,HUNK,ATAT1,STX1B,SEMA6D,R3HDM2,NLGN1,KDM4D,SLC12A4,BTBD7,ATF7IP,ZFP1,ANKRD36,MBD5,USP33,DOP1A,ZSWIM8,SP4,PEG10,RBM26,LARP4,STAU1,ELOVL4,SULF2,NSFL1C,JMJD6,SYN1,ANKRD28,PJA1,CAMTA1,MLST8,SIN3B,KIAA0930,TRIM2,RPGRIP1L,CLASP1,SYNE1,RNF216P1,TEK,DICER1,ENHO,FAM124A,TPM1,RGMB,METTL3,ELP5,STXBP4,OSBP2,BCL2L13,CCDC14,XPO1,ZNF711,ELFN1,TMEM237,DPYSL5,EMSY,GDPD5,HPS4,FIP1L1,PLSCR4,DNAH10,DOCK8,UBE3B,HNRNPA3,NETO2,NETO1" MicroRNA hsa-miR-192*:mirSVR_lowEffct hsa-miR-192*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.43E-70 4.72E-66 5.16E-69 4.75E-68 210 1386 "KCNH8,GALNT16,RNF150,BEND6,INTS2,TXNDC16,ALCAM,CEP126,CARNS1,UNC79,AMPH,ZFAT,OGT,DPP10,MAP4K3,LINC00173,CCDC74A,ATP2A2,RNF182,BACH1,CFLAR,KSR1,MTMR3,CBLN1,DGKI,LRRFIP1,DLGAP1,CFL2,SRSF11,SOCS6,CHN1,CLTC,QKI,SRP14-AS1,HECTD1,MAP4K4,SLC4A8,SMARCAL1,TOGARAM2,PREPL,HAPLN1,GDA,SNCAIP,CSF2RA,IPCEF1,SIPA1L1,CST3,UBXN2A,CCDC144A,BOC,GPRASP1,IST1,DGKB,SCRN1,DNAL1,ARMCX4,TMEM130,RHOBTB1,DMTF1,SLC12A6,PDCD6IP,DNM1L,WDPCP,FSD1L,EIF5,IRAK4,EMX2,EPB41,ENPP6,SRRM1,NCALD,NRN1,F5,TAOK3,RACK1,FGF13,SEC23B,SEMA4D,NOP56,WDR83,SARAF,B4GALNT1,ZNF234,INPP5K,GHR,ADGRA3,MCHR1,GRIA2,PLCD4,GRM8,FAM19A2,RNFT2,ADAMTS6,MAP4K5,IRAK3,FRMD3,C2orf72,IL6ST,ITPKB,SLC35G1,KCNK3,KCNN2,KIF5A,IPO5,HECTD2,GPR155,MARK1,MBNL1,MIA2,HS6ST3,MYO9A,BEX5,CNOT4,NOVA1,NTRK3,OPRL1,OXTR,CDK18,PLCL1,PURG,MAPKAP1,STRN3,SCHIP1,MAGEL2,FSD1,PRKACB,CEP41,PTN,STK32A,PTPRD,TUG1,ZNF844,PID1,ZNF793,FAM184A,MSANTD2,SLC25A36,RNASEL,TMLHE,GSTCD,ROBO2,BAALC,ATP8B4,ZNF568,ZNF331,FNIP1,HSPA4L,SH3GL3,PPM1E,FNDC3A,WDR37,TRIM67,ELMO2,SLC22A4,IFT122,MBD5,SNRPN,TRERF1,BDP1,FNBP1,HECW1,KDM4C,MCF2L2,ZNF621,SEPT8,KLHL7,NUDT10,COBL,TAL1,ADGRL3,AGTPBP1,TBCEL,FBXW11,TBL1X,DMXL2,TRIM2,GPRIN3,AP4E1,TLR4,ERCC6L2,TMPO,RIMBP2,KAT6B,TP53BP2,TPM1,RGMB,METTL3,PDSS1,TRO,TTC3,ZKSCAN5,SGK3,UGT8,ZNF709,VLDLR,CLDND1,ZBTB14,TRIM9,MEIS3,INTS3,EVI5,GAL3ST3,FAM47E,PARP11,RTN4,UBE3B,JMJD1C,TRAM2-AS1,KLHDC1,SENP7" MicroRNA hsa-miR-3168:mirSVR_highEffct hsa-miR-3168:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.00E-69 5.62E-66 6.14E-69 5.65E-68 175 972 "CLK4,NCKAP5,ADCY8,GALNT13,INTS2,KCTD16,OSBPL1A,ALCAM,ARHGAP20,PCDH10,CCDC146,DDO,LGR5,ZSCAN18,EIF4G3,ATP2A2,AZGP1,DST,SCAPER,JAZF1,CA8,CALB1,KALRN,CH25H,CHGB,CHN2,B4GALT6,TPP1,ABCG2,FAM149A,ABI3BP,RTTN,ANKRD44,SOCS5,PDE4DIP,CST3,FAM169A,APPL1,ZSCAN23,DCAF4,ARHGAP32,DCAF8,LONRF1,MYEF2,PLPPR4,SPOCK3,WDR20,EXOG,RAB39B,CDON,CASP8AP2,WDPCP,RASGRP1,PHF20L1,PLEKHA1,EPB41L2,SRRM1,ZNF589,FER,FGF11,UBE2E3,SYNCRIP,FLT1,PDLIM5,CELF1,CGREF1,STAU2,MEGF10,GABRA3,ZNF559,GGTA1P,GHR,PPARGC1A,HPGDS,MSL3,KDM2B,PRUNE2,FUT10,GPR37,CNTRL,GRM8,CIT,FAM19A2,UBE2QL1,TOX2,ZHX1,MIER3,ELOVL5,HNMT,CFAP126,IRF8,MSL1,LRRCC1,INSM1,KCNN2,MAP4,MBNL1,TM6SF1,MEIS1,ZNF680,TAGLN3,MYCN,MYO9A,NF1,SLC11A2,NRCAM,NTRK3,OXTR,OLA1,ZNF655,XRN1,GPSM2,JAKMIP1,DRAM2,GRAMD1C,GDPD1,SNRK,TMEM260,PTPRE,RAP1GDS1,RBBP6,GTDC1,RGS12,TMLHE,EXD2,ROBO2,YY1AP1,CCDC102B,NEK11,ABCA11P,KCNIP1,TRAPPC13,AP1AR,SEC14L1,KIF27,TRA2B,SEC31A,ABLIM3,DOK5,SP4,ERC1,RBM26,LMO3,ATP10B,NXT2,SYNE2,VPS13A,PLCB1,FAM208A,ADGRL3,NAT16,FRYL,ZMAT3,SLC44A1,TK2,BHLHB9,TMPO,TPM1,TRIO,DCBLD1,CLHC1,USP1,CCDC14,ZNF781,REEP1,FSTL5,ZNF225,EMSY,MDH1B,FAM13C,DOCK8,RTN4,KAT6A,IFT88,NETO1" MicroRNA hsa-miR-122:mirSVR_lowEffct hsa-miR-122:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-69 5.79E-66 6.32E-69 5.82E-68 200 1264 "VWA5B2,RALGAPA1,ABR,ASIC1,NDRG3,FMNL2,GALNT16,ADCY6,TMCC3,PTCHD1,HECW2,ANK2,FGD2,LCORL,APBA2,PHYHD1,MARCH3,CCDC74A,CHRD,STX16,LDHD,WASF1,DDR1,LURAP1,KALRN,CLDN10,LRRFIP1,EVI5L,CCPG1,CACNA2D2,SRSF11,ARHGAP22,SLIT2,EPS15L1,RAB33A,NRXN3,FBXO7,QKI,SRP14-AS1,IGLON5,SUMF2,BAG4,SLC35F1,RGS6,CST3,PLXNA4,LONRF1,DGKB,ZBTB24,ELMO1,SNAP91,SPOCK3,GRIN3A,SLC12A6,AASDH,EDN1,EDN3,CNNM1,TMTC1,EGFR,STARD3NL,EPB41L2,RCAN2,EPHB1,CD320,TBC1D16,FKTN,ZSCAN30,ZNF589,OLFM1,IP6K2,PCYOX1,SEMA4D,FLT1,ANKFY1,EFCAB2,AK8,CAMKK2,ATP6V1H,STAU2,NEURL4,HRASLS5,C15orf41,PCDH17,GGTA1P,TMEM121B,DIDO1,BTN2A1,GSTT2,ZBTB49,PSIP1,GUCY1A1,BACH2,HLF,NEGR1,HSPA1L,IDH3B,NKD1,NME9,C2CD4C,KCNJ5,CYP27C1,KTN1,PAXBP1,MARK1,LYPLAL1,MEIS1,MID1,MITF,GIT1,SAMD5,ADAM22,MYT1,NELL2,PDE1C,OLA1,NLGN3,SCHIP1,ING3,POLR2F,PPP2R5E,MAPK4,MAPK9,RELN,PTPRO,TUG1,OXR1,NUDT11,CCDC82,ATAT1,KCNIP1,DGLUCY,SATB1,SCP2,GALNT10,TRA2B,FAM102A,PPM1E,FERMT1,SLA,WDR47,FAM214B,ATF7IP,SLC22A4,COA1,MBD5,SNRPN,FAM219A,PDZD2,BDP1,SOX11,NMNAT2,HECW1,PEG10,ZC3H13,SPTB,SAMSN1,SEPT3,SYNE2,RHBDL3,KIAA1107,IQCE,SIN3B,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,ZFPM2,SLC44A1,ERCC6L2,RIMBP2,C9orf85,ZNF346,ELP5,TRPS1,SLC35A4,LINC00689,PLEKHH2,P2RY12,ZBTB14,ZNF19,ZNF24,ATP6V0E2,ZNF142,REEP1,SLC38A1,VPS35L,SIGLEC10,KCNAB1,DOCK8,MSRB3,ADAMTS10,FXR1,ST8SIA2" MicroRNA hsa-miR-1185:mirSVR_lowEffct hsa-miR-1185:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-69 6.26E-66 6.83E-69 6.29E-68 189 1133 "KCNH8,ACADM,NCKAP5,WDR35,OSBPL8,SPOP,SRPX,MARCH4,ANK2,C6orf89,EPB41L5,BCAS1,USP37,PLA2G4C,SEC11C,BMPR1B,IL33,DDR1,CACNB4,CALM1,KALRN,VXN,CAST,PRC1,CBLN1,USP6,MTMR7,LRBA,SEPT7,DCLK1,LOC730101,DLGAP2,CFL2,SRSF11,PLEKHB1,CLTC,FBXO7,SRP14-AS1,HECTD1,CNGA3,AKAP7,RCHY1,BAG4,CPS1,ENTPD4,CRY2,GDA,CRYM,RGS6,SEC24C,SUSD5,PHACTR3,CTH,HDAC9,IST1,MFAP3L,SGSM2,DPH1,MAMLD1,FIS1,E2F6,EDIL3,FCF1,FRY,EPB41L2,ZNF549,ZNF589,SLC9B2,POLK,SUCO,SCARA3,SEC23B,SYNCRIP,STAMBP,TPK1,ATP2C1,DLL3,STAU2,MEGF11,TMEM8B,LRRC37A6P,AHDC1,LYVE1,BRD8,SPIN1,GPD1,GRIA2,ADAMTS13,RNF165,NCKAP1L,ZNF491,NEGR1,SHISA6,ZNF678,KCNH2,LMO2,SYTL4,HECTD2,ASPRV1,MAP4,MARK1,LYPLAL1,MEIS2,MMP16,MSR1,NRBP2,LAYN,ZC3H12B,NEK1,CNOT4,NOVA1,DNHD1,LOC100128398,CLDN11,PCDH9,GNG2,SNX10,RETREG1,PDZRN4,RETREG2,PPP2R5E,PPP3CA,RASGEF1B,PRKACB,LAMA1,CNTLN,NCR3LG1,SPDL1,PPP2R3C,TMEM255A,ZNF793,SH3TC2,RASGRF2,GTDC1,CARF,GSTCD,SPIN3,RPS6KA2,SEMA6D,ATXN7,FNIP1,COPZ1,KIF21A,FERMT1,ST6GAL1,CCDC92,BTBD7,ATF7IP,MYH15,TMCC1,FAM126B,SP2,GLT8D1,SPART,LHPP,SSTR1,NKAIN2,NXT2,ST5,STAU1,NEK4,KANK1,SUPT5H,VPS13A,ANKRD28,SIN3B,CUX2,TPCN2,USP32P1,RNF216P1,AP4E1,AKTIP,SLC44A1,ERCC6L2,NPL,NR2C2,STXBP4,RUSC1,HIRA,XPO1,ZNF74,MKRN3,ZBTB38,ADAMTS9,NAV3,PDSS2,KAT6A,IFT88,NETO1" MicroRNA hsa-miR-935:mirSVR_highEffct hsa-miR-935:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-69 6.61E-66 7.20E-69 6.63E-68 168 896 "RALGAPA1,GALNT13,HACE1,OSBPL6,CC2D2A,PCDH10,GPRASP2,SYT13,DPP10,MAP4K3,APAF1,APC,CDC14B,TMEFF1,RGS20,CADPS,STK33,ATP1B3,STX16,ATP2A2,SYNJ2,MTMR2,IL33,ZNF555,KALRN,CBR1,KRIT1,MTMR7,SYNGR3,CFL2,RCBTB2,SRSF11,LY86,LETMD1,SLC4A8,ABI3BP,CSNK1G3,SIPA1L1,SOCS5,PDE4DIP,PLXNA4,DZIP3,KIAA0586,DBN1,MYEF2,ZC3H11A,GRIN3A,RAB39B,DMD,NR1D2,DNAJB6,ABCC5,DNM1L,EBF1,WDPCP,EDNRA,MBNL2,EIF4G2,TENM1,GPHN,ADGRV1,DLC1,SLC9B2,FGF1,FHL1,C2orf88,TPK1,KHDRBS3,STAU2,SARAF,MEGF10,GABRB3,RAPGEF6,DISC1,GCNT2,TUBGCP4,SESN1,PCDH17,GGT7,MALT1,COPS8,SPIN1,GLUL,ZNF638,MAP7D2,GUCY1B1,GABARAPL2,LRRCC1,KCNJ16,KTN1,PAXBP1,LMO2,NCOA7,SMAD1,GPR155,MAT2A,SHC3,MIA2,SCAMP5,AFDN,MN1,ZNF680,MYO9A,MYT1,NACA,P2RY13,NEK1,NF1,CNOT4,PCDH9,PRTG,ABCB1,FAM218A,XRN1,PCDH18,MTRF1L,PURG,SH3KBP1,LRRN3,GRAMD1C,PRPSAP2,RELN,PTPRB,CEP97,FAM184A,RADX,ROBO2,PCMTD2,CCDC102B,FBXW7,ZNF331,RMI1,SH3GL3,SHMT2,FBXO11,FNDC3A,CNKSR2,FAM81A,PPP4R3A,WDR47,CCDC88A,SLC12A2,ATF7IP,ZKSCAN3,DOK5,SP2,CLSTN2,POGZ,LARP4,RGL1,ADHFE1,PRRC2C,PLCB1,C12orf76,MGRN1,TRIM2,PUM2,TMPO,TP53BP1,TTC3,PLEKHH2,CLDND1,ZNF184,EMSY,VPS35L,MPPE1,FBXO36,NETO1" MicroRNA hsa-miR-4312:mirSVR_lowEffct hsa-miR-4312:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-69 7.51E-66 8.17E-69 7.52E-68 190 1146 "KCNH8,ACADM,KDM5D,ESYT2,HECW2,KIAA1324,OSBPL6,SEMA6A,ARHGAP20,EP400,APOC1,PPFIA3,ARRB2,ASGR1,PCDHGB4,EIF4G3,ATP6V0A1,ADAM23,AZGP1,BCHE,NAE1,IL33,VXN,CAST,CARS,DGKI,NUMBL,TPP1,STOML1,SRP14-AS1,AKAP6,WHRN,LETMD1,TOGARAM2,SLC35F1,C2CD2,TRIM69,SEC24C,APPL1,PPP6R2,RUBCN,KIAA0408,RASSF2,DGKG,KIAA0319,CDON,DPH1,PDCD6IP,ARRDC4,EDNRA,ANKRD46,PHF20L1,SUGP2,KMT5B,GOLGA7,VPS13B,ERCC2,DENND4A,RRAGB,EZH1,RACK1,FCGR1A,FKTN,ZSCAN30,FECH,SEC24B,FGF13,FHL1,SCARA3,HPCAL4,FOXF2,SYNCRIP,FLT1,NOP56,C2orf88,EFCAB2,PDLIM5,STAU2,DOT1L,HRASLS5,MSTN,TMEM121B,STMN2,PLPP7,PRDM5,CIT,HAS2,DDX19B,HLF,HNMT,IDH3B,DISP2,INPP5B,KCNH2,KCNJ16,A1BG-AS1,KTN1,LAMP2,PACRG,MATN3,MBNL1,CHIC1,XRRA1,ADAM22,PTOV1,MXI1,NEXMIF,NF1,ALDH1L2,NTRK3,NUCB2,P2RX7,P2RY1,CNTN3,PCDHGC3,SERPINI1,DRAM2,ELOVL2,ZIK1,PTX3,TMEM255A,SH3TC2,UBR7,RGS4,ALG9,ZC3H14,EMID1,RMI1,SBF1,GALNT10,SH3BGR,AMBRA1,WDR37,SLC8A1,ARHGEF40,CXXC4,SMARCD3,KIF13A,CABCOCO1,PDZD2,BDP1,KDM4C,UNC5B,DBNDD2,ZBTB43,PBLD,ZSCAN29,NSFL1C,SYNE2,VPS13A,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,DICER1,TMEM121,AP4E1,ERCC6L2,R3HDM1,NPL,TRO,HSPBP1,CLDND1,GUSBP1,PCDH20,ZNF28,LYPD6,EML6,DNALI1,MDH1B,WNK3,FZD3,HNRNPA3" MicroRNA hsa-miR-628-5p:mirSVR_highEffct hsa-miR-628-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-69 7.88E-66 8.57E-69 7.89E-68 164 854 "SYN3,EMILIN3,OLMALINC,RTL9,TXNDC16,AMT,CCDC146,UPRT,DDO,USP37,PPP4R4,LINC00173,ATP2A2,BCL7A,BLM,PROM1,CASTOR3,C5,GPC2,PTBP2,CAMK2G,CAST,USP6,LRBA,NUMBL,COPB2,SRSF11,B4GALT6,C4orf33,QKI,TOGARAM2,SEC24C,VCAN,UBXN2A,PHF14,RIMS2,BOC,DOCK4,HDAC9,KATNAL2,ARHGAP24,GSDME,DMD,NR1D2,GOLT1B,AASDH,WDPCP,EDN1,KMT5B,EGR3,C8orf37,PAN3,RCAN2,NRN1,RACK1,FER,FGF1,TMEM164,NBEA,PDLIM5,OGA,MTHFD2,LRRC37A6P,MSTN,SPIN1,MSL3,ZNF638,LOXL3,ADGRA3,PLCD4,RASSF8,ARHGAP36,HNMT,SMAP1,KIAA1755,IL6ST,IPO5,KTN1,HECTD2,MAT2A,MBNL1,MEIS1,MEIS2,PPM1L,MMP16,NELL2,NUCB2,CHAMP1,CDK18,ZFYVE21,PRIMPOL,STRN3,SDK2,MAGEL2,RANBP3L,PKIA,MAPK9,HYDIN,PTN,PID1,CEP97,ZNF793,FAT4,ZMAT4,RIC8B,RNASEL,CARF,MRAP2,ATP8B4,STK32B,MEG3,ZNF568,TRAPPC13,ATXN2,FOXRED1,HKDC1,CHD9,SLA,SLC6A11,ZFP1,MYH15,RCOR3,CMTR2,USP33,SP2,SP4,ATP10B,NKAIN2,NXT2,RGL1,PRRC2C,NUDT10,ZFP90,SZT2,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,RNF175,ITGB3BP,AP4E1,BEX4,GUSBP1,XRCC4,PCDH20,MICU3,KCNT2,TRIM9,ZNF540,ZSCAN26,ANKS1B,SMARCAD1,RNF103,TMEM178A,HPS4,KCNAB1,DOCK8,RNF170,ZDHHC20" MicroRNA hsa-miR-890:mirSVR_highEffct hsa-miR-890:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-69 8.04E-66 8.73E-69 8.04E-68 185 1088 "RALGAPA1,CLK4,FMNL2,ADD2,RNF150,PTCHD1,ADGRF5,AMPD3,PHF12,APBA2,BCAS1,NCOA1,ATP6V1G2,RGS11,SYNJ2,SCAPER,MTMR2,IL33,THSD7A,CALM1,KALRN,PTBP2,RUNX1T1,KRIT1,USP2,C1orf52,DGKI,B4GALT6,NDST3,LHX2,RAB28,NRXN3,C4orf33,CNGA3,AKAP7,ARMC8,COL4A5,AHCTF1,ZFP28,CNRIP1,HAPLN1,ARHGEF10,CSNK1G3,RUBCN,GAPVD1,MATR3,PABPC5,GIT2,PITPNC1,HEPH,MYEF2,ELMO1,FBXL5,RHOBTB1,SV2B,EXOG,GRIN3A,HS3ST2,USP3,DYNC1I1,CPEB2,ECM2,AASDH,EDNRA,FRY,CELSR3,COPS4,PLEKHA1,C8orf37,EPB41L2,TLR7,CLVS1,PPP1R1B,FER,FGF11,MAD2L2,POLK,ATP13A4,MSANTD4,OGA,GABRG2,GALC,MTHFD2,MSTN,AHDC1,GLI2,LUZP2,GNG4,PCLO,GRB10,GRIA2,ZNF496,BVES,UBE2QL1,ARHGAP36,MIER3,LRRC75A,SMAP1,IDH3A,ZNF181,IL6ST,FAM69A,KIF5A,KIT,ZFYVE27,MATN3,MBD1,MBNL1,MITF,MN1,ZNF92,MYCN,MYT1,NF1,NRCAM,NUCB2,GLIPR1L2,PCDH8,PDE1B,PURG,SDK2,MINDY2,GRAMD1C,TMEM260,ZSCAN32,PTPRB,ZNF615,CCDC40,FAM66C,GTDC1,RGS12,ZFHX4,SETD5,TMLHE,NEK11,MCMBP,ADAL,LRRK2,SATB1,ATXN2,SCP2,TRA2B,CHD9,DZIP1,CCDC88A,TET1,CDK5RAP2,ANKRD36,LIMCH1,SNAP25,CABCOCO1,SNRPN,USP33,DOK5,KDM4C,DBNDD2,MCF2L2,RBM26,SPART,MPRIP,STAU1,RGL1,ARHGEF9,SYPL1,SYT1,PJA1,FAM208A,ZFP90,PCDHB9,PCDHB4,OBSL1,USP32P1,SIRT1,C18orf54,TLR4,TRPS1,PPIL6,OSBP2,LYPD6,FSTL5,EMSY,CADM2,ADAMTS9,JMJD1C,FRMD6" MicroRNA hsa-miR-586:PITA hsa-miR-586:PITA_TOP PITA 1.46E-69 8.16E-66 8.85E-69 8.15E-68 132 539 "FMNL2,KLHL32,HECW2,PCDH19,ALCAM,ABCD2,CDC42BPA,LRCH2,PPP4R4,NCOA1,ATP2A2,ZNF583,JAZF1,SGCE,CABP7,CALM1,CAMK2G,SEPT7,ZMYM4,FOXN3,NRXN3,CLTC,MAP4K4,IQCK,LETMD1,PREPL,GDA,CS,SEC24C,CSNK1G3,ERC2,HDAC4,ZFYVE16,DGKB,SCRN1,SPOCK3,WDR20,NR1D2,CPEB2,RCAN1,GOLT1B,MBNL2,EMX2,NCALD,ACSL4,SEC24B,OLFM1,MEX3B,AFF2,PDLIM5,FUT9,FYN,MSTN,PCDH17,KDM2B,HTATSF1,FERMT2,PCLO,ADAMTS6,MAP4K5,BACH2,HLF,NEGR1,IGF1,KCND2,KCNQ3,TTYH2,MARK1,MBD1,MBNL1,MEIS2,KITLG,NEFM,NFIX,CNOT4,NPY,GPR137C,PDE4B,PDE4D,OLA1,PIK3R1,XRN1,STRN3,LRP12,PPP3CA,SNRK,PID1,RDX,UBR7,PRIMA1,RIC8B,CARF,ROBO2,RORB,MRAP2,FBXW7,RTN1,CSRNP3,CASC3,WDR47,PKNOX2,CCDC88A,CPEB4,SOX11,POGZ,ERBIN,STXBP1,NECAB1,VPS13A,PLCB1,CAMTA1,ADGRL3,TCF4,SATB2,RPGRIP1L,TCF12,FRYL,TEK,AKTIP,SLC44A1,R3HDM1,TNS1,KCNE5,UBE2H,TBC1D15,ZIC2,ZNF711,DPYSL5,RNF103,RGS7BP,RTN4,HNRNPA3" MicroRNA hsa-miR-141-3p:TargetScan hsa-miR-141-3p TargetScan 1.52E-69 8.50E-66 9.20E-69 8.47E-68 144 651 "C3orf14,NCKAP5,KIAA1211,MTA3,OSBPL1A,OSBPL6,AMPD2,OGT,ANK2,APBB2,IGDCC4,ARNTL,CDK13,DNAH17,ATP2A2,NRP2,CACNA1I,GPC2,LDLRAD4,CACNA2D1,CDC25B,LONRF2,EVI5L,NUMBL,CFL2,FOXN3,PLEKHB1,PPT2,QKI,HECTD1,MAP4K4,CNTN1,MYRIP,CLOCK,CDC42BPB,CRMP1,ANKRD44,CSNK1G3,PLXNA4,ERC2,PLCXD3,KIAA0408,DOCK4,ARHGAP24,HDAC4,MATR3,DAPK1,RHOBTB1,CHRDL1,GRIN3A,CDON,HIPK3,FSD1L,PLXNC1,EIF5,RGS17,GPHN,IGSF6,KATNAL1,DLC1,OLFM1,FGF13,ANKFY1,KHDRBS3,CELF1,MSANTD4,GCNT2,RAB30,GPR75,CBX1,KIAA1958,KDM2B,GPD1,GPR12,GRIN2D,RASSF8,BACH2,MIER3,HLF,ACOT7,HNMT,AGFG1,MSL1,IPO5,LSAMP,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,AFF1,MMP16,MN1,MYO5A,MYO9A,NPTX1,NRCAM,P2RY1,GPR137C,PCDH8,PLCL1,SCHIP1,PPP2R2B,PPP2R5E,PRKACB,PTCH1,PTPRD,PTPRG,MARCH1,KHDRBS2,ATXN7,SCN7A,SCAF8,PPM1E,CHD9,DZIP1,ATF7IP,CPEB4,CXXC4,RCOR3,MBD5,FAM126B,PDZD2,KDM3A,HECW1,NFASC,LMO3,CLASP2,MPRIP,NECAB1,EXOC7,CBX5,ASXL3,LRRC8A,KAT6B,NR2C2,BCL2L13,CLIP2,LYPD6,CADM2,PRDM10,RGS7BP,JMJD1C,FRMD6" MicroRNA hsa-miR-200a-3p:TargetScan hsa-miR-200a-3p TargetScan 1.52E-69 8.50E-66 9.20E-69 8.47E-68 144 651 "C3orf14,NCKAP5,KIAA1211,MTA3,OSBPL1A,OSBPL6,AMPD2,OGT,ANK2,APBB2,IGDCC4,ARNTL,CDK13,DNAH17,ATP2A2,NRP2,CACNA1I,GPC2,LDLRAD4,CACNA2D1,CDC25B,LONRF2,EVI5L,NUMBL,CFL2,FOXN3,PLEKHB1,PPT2,QKI,HECTD1,MAP4K4,CNTN1,MYRIP,CLOCK,CDC42BPB,CRMP1,ANKRD44,CSNK1G3,PLXNA4,ERC2,PLCXD3,KIAA0408,DOCK4,ARHGAP24,HDAC4,MATR3,DAPK1,RHOBTB1,CHRDL1,GRIN3A,CDON,HIPK3,FSD1L,PLXNC1,EIF5,RGS17,GPHN,IGSF6,KATNAL1,DLC1,OLFM1,FGF13,ANKFY1,KHDRBS3,CELF1,MSANTD4,GCNT2,RAB30,GPR75,CBX1,KIAA1958,KDM2B,GPD1,GPR12,GRIN2D,RASSF8,BACH2,MIER3,HLF,ACOT7,HNMT,AGFG1,MSL1,IPO5,LSAMP,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,AFF1,MMP16,MN1,MYO5A,MYO9A,NPTX1,NRCAM,P2RY1,GPR137C,PCDH8,PLCL1,SCHIP1,PPP2R2B,PPP2R5E,PRKACB,PTCH1,PTPRD,PTPRG,MARCH1,KHDRBS2,ATXN7,SCN7A,SCAF8,PPM1E,CHD9,DZIP1,ATF7IP,CPEB4,CXXC4,RCOR3,MBD5,FAM126B,PDZD2,KDM3A,HECW1,NFASC,LMO3,CLASP2,MPRIP,NECAB1,EXOC7,CBX5,ASXL3,LRRC8A,KAT6B,NR2C2,BCL2L13,CLIP2,LYPD6,CADM2,PRDM10,RGS7BP,JMJD1C,FRMD6" MicroRNA hsa-miR-513c:mirSVR_highEffct hsa-miR-513c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-69 8.69E-66 9.40E-69 8.65E-68 190 1147 "ACADM,DPY19L2P4,INTS2,HECW2,ALCAM,SRPX,OGT,LCORL,LGR5,PPP4R4,MARCH3,NUMB,EIF4G3,ATP1B3,N4BP2L1,LINC00847,CALM1,KALRN,VXN,ZNF501,LRBA,SEPT7,CCPG1,QKI,MAP4K4,ARMC8,FAM171B,PREPL,RBM39,RNF14,MROH8,CSNK1G3,SOCS5,KIAA0586,DGKB,TMEM170A,GIT2,FAM107B,DYNC1I1,DPH1,RCAN1,EDNRA,FCF1,FRY,PHF20L1,SUGP2,DCTN4,LRRC17,STX2,SIRPB1,EXTL2,ADGRV1,F5,FAM198B,GORAB,FGF1,POLR1B,SYNCRIP,NBEA,SMC2,ST6GALNAC3,MSANTD4,OGA,MEGF11,GAD1,GATM,NEU3,MSTN,ADAM28,PCDH17,GHR,LYVE1,GPR75,CBX1,DCLK2,GPD2,TMEM121B,DIDO1,SERP2,BTN2A1,PSIP1,RNFT2,TOX2,ARHGAP36,AGBL5,HSF2,IDH3A,NCOA7,MBNL1,TM6SF1,MITF,AFDN,MMP16,ZNF680,SAMD5,ZNF92,MYO9A,NEFM,NEFH,NF1,VWA2,CNOT4,NOVA1,GNG2,OLA1,NALCN,CCSER2,SNX10,MINDY2,PPM1B,RASGEF1B,MAPK10,MASP1,CNTLN,PTX3,ZSCAN2,PID1,OXR1,ZDHHC14,RET,ERI2,RFX3,ZFHX4,CARF,GSTCD,CCDC25,RPL15,ATAT1,KCNIP1,FNDC3A,PEX26,PPP4R3A,SLC6A8,CCDC88A,NAPB,SNCA,ZNF415,BDP1,KDM4C,RBM26,ATP10B,PBLD,TROVE2,CLSTN2,NECAB1,DNAJC9,SYPL1,PJA1,ADGRL3,AGTPBP1,KLHL4,DOCK9,GPRIN3,PMS2CL,ITGB3BP,AP4E1,AKTIP,ARL10,TIAM1,TPM1,NPL,SYNPO2,RUNDC3B,AMACR,TSN,SGK3,RPL7L1,UBE2H,UBE3A,PLEKHH2,RICTOR,ZNF711,ZNF708,ZNF17,MICU3,FSTL5,ANKS1B,PRDM10,RNF103,HPS4,CIAPIN1,KCNAB1,RGS7BP,AMN1,DOCK8,PHTF2,JMJD1C,TIGD6,FXR1,NETO1" MicroRNA hsa-miR-3173:mirSVR_highEffct hsa-miR-3173:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-69 1.15E-65 1.24E-68 1.15E-67 186 1102 "KCNH8,SYS1,TMCC3,ADD2,ADRA1B,KIAA1324,CC2D2A,SRPX,ZNF687,MYH7B,APAF1,SHROOM2,CDC14B,SPTBN4,TMEM108,ATP6V1G2,CFLAR,KSR1,KALRN,PTBP2,ARHGEF25,CBR1,USP6,MAGI1,TIGD7,CHN2,CLCN3,TPP1,SRP14-AS1,ARMC8,CNRIP1,CS,VCAN,PDE4DIP,PHF14,ARHGEF4,PPP6R2,ARHGAP24,ZFYVE16,ZNF337,DAPK1,PABPC5,EXOG,RAB39B,DMD,CDON,DMTF1,CASP8AP2,ACOT8,DTNA,ANKRD46,FSD1L,CELSR3,PHF20L1,APH1A,RASGRP2,EPHB1,SIRPB1,EXTL2,EYA1,CLVS1,CORO2B,PRMT5,KAT8,FER,OLFM1,RGPD5,PSD2,NELFCD,POMT1,FYB1,GATM,NEU3,GGTA1P,LYVE1,TNRC6A,GLUL,RAB40B,FUT10,GRM2,LINGO1,ADAMTS6,MAN1B1,SHISA6,MSL1,ZIC5,ITGAM,KCNQ3,TTYH2,LSS,ZFYVE27,MATN2,TM6SF1,MEIS1,ADAM22,NEFH,NF1,ALDH1L2,CNOT4,NOVA1,NTRK2,NTRK3,GPR137C,OLA1,NALCN,ZNF655,PLCB2,SMOX,TRHDE,HYDIN,BCAS3,VPS13C,QRICH1,PTCH1,PTK2,TMEM260,PTPRB,ZSCAN2,NKAIN1,MARCH1,RAD51D,MORC4,GSTCD,YY1AP1,CCDC102B,FBXW7,BAALC,ZNF671,STK32B,MAP6D1,FAM192A,SEMA6D,SEC14L1,CASC3,CHD9,PPP4R3A,PKNOX2,CCDC88A,SLC9A5,ANKRD36,ANKFN1,PDZD2,TRERF1,SOX15,ZSWIM8,ZC3H13,IQSEC2,ZC4H2,SEPT8,TTBK2,ARHGEF9,DNAJC9,COBL,ANKRD28,TACR1,RPGRIP1L,GPRIN3,FRYL,AP4E1,SLC44A1,TMEM9,HEY1,BHLHB9,LRRC8A,TPM1,CDK20,NPL,TPM2,METTL3,RUNDC3B,RUSC1,HSPBP1,CCDC136,TBC1D15,WIPF1,ZNF781,ZNF17,MKRN3,CELF4,SMARCAD1,FIP1L1,ST7,MARCH8,KAT6A,PHTF2,NHSL1" MicroRNA hsa-miR-26b*:mirSVR_highEffct hsa-miR-26b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-69 1.26E-65 1.35E-68 1.25E-67 207 1356 "KCNH8,XKR4,NDRG3,FMNL2,KLHL32,ADCY8,ADD2,AXIN2,BRAP,BEND6,CC2D2A,SPOP,OGT,LRCH2,EP400,CCDC146,PKP4,DDO,TNRC6C,ZFYVE28,NCOA1,RASL11B,SLC4A4,EIF4G3,ATP1B3,ADGRB3,BBS2,NRP2,FUBP1,SCAPER,CASTOR3,C5,CA8,CALM1,RUNX1T1,CERS5,MTMR7,CD38,LRBA,NOG,PLEKHB1,CNOT8,NDST3,SLIT2,CLTC,FHL5,IQCK,ARMC8,ZNF521,NECTIN3,CLIP3,SNCAIP,CSF2RA,ARHGEF10,APPL1,PHF14,GREB1,BOC,DOCK4,GAPVD1,TMEM170A,SPOCK2,ZBTB24,HEPH,FBXL5,GSDME,PDCD6IP,DTNA,HIPK3,KLHL5,OPTN,YAF2,FAM13A,CALCRL,EMX2,EPHB1,GPHN,ADGRV1,ABCA8,ACSL4,SCML2,CEP78,FDFT1,FGF1,OLFM1,SUCO,RGPD5,NOP56,WDR83,STAMBP,ABLIM2,SDCBP2,ZMAT1,FAM120B,ACSS1,KIAA1841,TUBGCP4,WASHC2A,PPARGC1A,COPS8,GLYR1,CBX1,GPD2,PRUNE2,TDRKH,MCHR1,ADAMTS6,TCEAL6,SMAP1,LRRCC1,NME9,KCNB1,KCND2,KCNN3,IPO5,STMN1,MAP4,MEIS1,SRSF12,AFDN,MMP16,NF1,NFE2L2,NOVA1,NPTX2,OGG1,LOC100128398,GLIPR1L2,PCDH9,PCSK5,ZNF655,FAM216A,PPP2R5E,MAPK9,MAPK10,GRAMD1C,GDPD2,CNTLN,ANKHD1,PTPRG,ACSM5,RAD51D,OXR1,ZMAT4,FIGN,RIC8B,NUDT11,ZFHX4,GSTCD,ATP8B4,GLDN,ADAL,LRRK2,SEMA6D,SH3GL3,ARX,FNDC3A,FHOD3,R3HDM2,SYBU,NLGN1,NUBPL,FAM214B,KANSL3,ATF7IP,RCOR3,ANKRD36,SNRPN,ZSWIM8,NMNAT2,ZC3H13,ZC4H2,ZSCAN29,NEK4,SEPT8,ARHGEF9,PLCB1,ANKRD28,TBCEL,FBXW11,ZEB1,CLASP1,SYNE1,CYB561A3,ERCC6L2,TPM1,NPL,SYNPO2,SMUG1,ZNF610,UBE2H,P2RY12,RICTOR,ZBTB14,ZNF19,ZNF540,CELF4,TMEM237,ZNF184,SMARCAD1,STOX2,PRDM10,NAV3,FIP1L1,RGS7BP,UBE3B,SNX14" MicroRNA hsa-miR-606:mirSVR_highEffct hsa-miR-606:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.26E-69 1.26E-65 1.36E-68 1.25E-67 188 1126 "RALGAPA1,ACADM,CLK4,NCKAP5,BRAP,HACE1,HFM1,FAM135A,LRCH2,EP400,APC,TNRC6C,ZBTB10,DPY19L3,ATP6V0A1,DOCK11,TTLL9,SEC11C,IL33,CA8,KALRN,VXN,RUNX1T1,METTL6,USP6,DGKI,TIGD7,CLGN,CFL2,NDST3,C7orf61,FHL5,CNR1,IQCK,ARMC8,COL9A1,AKAP5,CRHBP,LRRC3B,CSNK1G3,SOCS5,CNTNAP2,PHF14,ZSCAN23,HDAC9,ARHGAP24,LIN54,MATR3,DBI,SPATA2,DDX46,SACS,DMD,USP3,CPEB2,DNAJB6,DNM1L,EBF1,FSD1L,MBNL2,KMT5B,RGS17,EPB41,EPB41L2,DENND4A,MRPL37,EYA1,EZH1,F5,FHL1,POLK,SYNCRIP,SMC2,UFM1,ERGIC3,ST6GALNAC3,STAU2,GAD1,RAPGEF6,MTHFD2,PPARGC1A,MALT1,GLI2,GLUL,GPR34,GPR37,FAM19A2,RABL2A,PSIP1,MAP4K5,RASSF8,TOX2,ZHX1,MIER3,SMAP1,MSL1,RBPJ,JAK2,SLC35G1,KCND2,KCNJ5,LIMS1,NCOA7,MAP4,MARK1,MBNL1,MIA2,MN1,MSR1,MYO9A,MYT1,P2RY13,NFE2L2,GPR137C,PAX6,ETFRF1,PCDH8,NALCN,PIK3C2A,PLCL1,PURG,LRP12,SCHIP1,PPM1B,LRRN3,PTPN13,EML5,USP47,RAD17,ZNF793,OXR1,RGS3,SETD5,ROBO2,PCMTD2,ABCA11P,RMI1,SEC14L1,HSPA4L,KIF21A,KIF16B,CPEB3,SHC4,FNDC3A,NLGN1,WDR37,CCDC88A,ELMO2,BTBD7,SNAP25,GLT8D1,KDM4C,ZC3H13,ZC4H2,NKAIN2,ELOVL4,NEK4,SYNE2,VPS13A,NUDT10,SYT1,ANKRD12,MTCL1,CAMTA1,DNMBP,TCF4,SATB2,PCDHGA11,PCDHB7,PCDHB6,SIRT1,AP4E1,TPM2,DCBLD1,FAM155A,WIPF1,WRN,SMARCAD1,SLC30A4,EMSY,MFF,PRDM10,FAM13C,KAT6A,SMIM8,PHTF2,KLHDC1,SENP7" MicroRNA hsa-miR-556-3p:mirSVR_highEffct hsa-miR-556-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-69 1.39E-65 1.49E-68 1.37E-67 184 1080 "SYS1,FMNL2,CCDC85A,ADRB2,AP2A2,MTUS1,AMT,OGT,DPP10,SLC4A4,STX16,ADGRB3,KSR1,DST,NAE1,DDR1,LOC730101,RCBTB2,CHN2,NDST3,IQCK,ABI3BP,CREM,CRHBP,HINFP,ANKRD44,ARHGEF10,CSNK1G3,SIPA1L1,PLXNA4,UBXN2A,RIMS2,USP6NL,CCDC144A,DOCK4,HDAC4,ZFYVE16,MATR3,DGKB,DNAL1,SV2B,FAM107B,ZNF582-AS1,CHRDL1,PDCD6IP,DNAJB6,EDN1,ANKRD46,KLHL5,PHF20L1,MBNL2,KCTD3,DCTN4,TUBD1,KATNAL1,GMPR2,ACSL4,CEP78,FCGR1B,FCGR3A,ZSCAN30,GORAB,FGF1,POLR1B,FGFR3,POLK,SUCO,VTI1B,FAM49B,ERGIC3,FYB1,TRAF3IP2,DISC1,IGSF5,ALDH1L1,SULT1C4,PPARGC1A,TCERG1,TNRC6A,ZNF638,FUT10,ATP2B1-AS1,GRIA2,FAM19A2,COQ10A,AP4S1,GUCY1B1,ZHX1,HLF,HNF4G,IDH3A,ZNF546,SLC35G1,STXBP5,STMN1,MBD1,MEF2C,MEIS2,SRSF12,NEK1,NFE2L2,P2RY1,DPY19L2P2,PCDH9,SERPINI1,NALCN,PIK3C2A,FAM218A,GPSM2,PLCL1,PPM1B,PKIA,MAPK9,STK32A,C1orf109,PID1,ZNF793,ZCWPW1,ZNF493,RBBP6,RGS3,ZFHX4,CARF,PCMTD2,RPE,ZC3H14,ZNF568,RYR3,NCBP3,AP1AR,SAFB,SEMA6D,SATB1,TNFRSF19,SEC14L1,SCAF8,CPEB3,FHOD3,BTBD3,KANSL3,BTBD7,ANKRD36,MBD5,SNRPN,PDZD2,TRERF1,HECW1,SPTB,RBM26,NXT2,STAU1,NEK4,VPS13A,TMEM150C,SYT1,MLST8,ADGRL3,FBXW11,TCEA1,ZEB1,PCDHB4,TEK,AP4E1,SLC44A1,SYNPO2,METTL3,KCNE5,TTC3,SGK3,BCL2L13,CLDND1,GUSBP1,LGI4,ZNF708,ZFAND5,CADM2,PRTFDC1,PRDM8,ADAMTS9,PDSS2,EPM2A,RGS7BP,HNRNPA3,NETO1" MicroRNA hsa-miR-1201:mirSVR_lowEffct hsa-miR-1201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.91E-69 1.63E-65 1.75E-68 1.61E-67 187 1116 "RALGAPA1,SYS1,GALNT16,GALNT13,ADD1,RNF150,HECW2,HFM1,SMIM17,ARHGAP20,PITPNM2,LCORL,APC,SHROOM2,SFMBT2,PCDHGB4,ZBTB10,TMEM108,ATP1A1,RIPK1,TTLL9,ADAM15,BACH1,BCHE,KSR1,SCAPER,SGCE,CACNA2D1,CALM1,ISPD,SLC16A4,LRRFIP1,EVI5L,MAGI1,CCPG1,NRXN3,PCYT1B,ANKRD35,AKAP5,ABI3BP,AHCTF1,ZNF521,SLC35F1,GREB1,PUM1,GPSM1,DCAF4,USP6NL,FAM131B,KIAA0408,DCAF8,PITPNC1,ZBTB24,MYEF2,KIAA0753,DNM1,EDN1,FRY,PHF20L1,TENM1,PLEKHA1,EPB41L2,IGSF6,TMEM132C,FDFT1,FER,MED12L,SPSB4,PRKAG2,SUCO,SYNCRIP,EVL,ANKFY1,ERGIC3,STAU2,AP4B1,MPP6,ZNF559,SEPT9,GPR162,USP19,TOX3,LUZP2,ADGRA3,FUT10,GRB10,SPACA9,GSTM5,TCEAL6,NME9,KCNN2,IPO5,MSR1,MXI1,NDP,NELL2,NF1,SLC11A2,LOC100128398,PCDHGC3,PDE4D,GNG2,SNX10,PNMA3,POLG,DRAM2,PPM1B,MAPK9,GRAMD1C,RELN,PIGG,SLC25A48,NWD1,RASGRF2,RDX,GTDC1,UBR7,NUDT11,C12orf49,ALG9,ARMH4,ZC3H14,TCP11L1,ST6GALNAC6,SATB1,SCP2,FERMT1,SHMT2,CHD9,SEC31A,ABLIM3,BTBD3,WDR47,SLC6A11,SEPHS1,CDK5RAP3,SLC12A2,SLC14A1,ZNF667,GKAP1,CDK5RAP2,MBD5,BDP1,TSNAXIP1,ZBTB43,DDN,NFASC,ZSCAN29,ZC3H4,TMEM150C,MLST8,SATB2,ZEB1,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB15,PCDHB7,CYB561A3,NR2E1,RIMBP2,METTL3,SMUG1,TRO,TSN,ZKSCAN5,HIRA,UBE3A,LINC00689,CLIP2,ZIC1,KCNT2,POLR3H,EMSY,HNRNPA3,NLRP3" MicroRNA hsa-miR-4292:mirSVR_lowEffct hsa-miR-4292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.24E-69 2.37E-65 2.55E-68 2.34E-67 228 1631 "ASIC1,XKR4,PSMG3-AS1,ADORA2A,UNC5A,KIAA1211,PTCHD1,BEND6,HECW2,SORCS2,SMIM17,SEMA6A,PCDH10,AMPD3,OGT,PHF12,EPB41L5,NT5C3B,PHYHD1,APOC1,TNRC6C,CPNE5,AQP6,PPP4R4,MADD,ARHGDIA,DNAH17,MARK4,ZSCAN18,NUMB,SLC4A4,ADGRB1,ADGRB2,RGS11,CFLAR,LDHD,ARHGEF7,CACNA1G,DDR1,CBR1,LDB2,DGKI,CDC25B,LRRFIP1,MAGI1,EPS15L1,IGLON5,ARHGEF6,PCYT1B,ARMC8,COL11A2,RCHY1,SMARCAL1,MYRIP,SEC31B,RBM39,SH2B1,CRYBB1,ANKRD44,RGS6,OSBPL3,KIAA0040,ERC2,RUBCN,ARHGAP32,KATNAL2,DGCR5,KIAA0753,C2CD2L,SGSM2,GRIN3A,NYAP1,DNAH9,SLC25A18,DNAJB6,RASA4,TNK2,C3orf18,ZNF549,ETV1,RASL12,F8,FAM198B,TBC1D16,SPSB4,FHL1,PCYOX1,AGAP3,FLNC,POMT1,SEPT9,GCK,ALDH1L1,MMADHC,GGT7,STARD3,KCNMB4,GPT2,LILRB4,GPD1,GRIK5,SERP2,CIT,SOX21,FAM107A,ATXN2L,BACH2,AGBL5,HNF4G,HNMT,C9orf129,DHX35,LRRC75A,SMAP1,MSL1,MYLK2,ZIC5,INSM1,C2CD4C,L1CAM,CAMK2N2,STMN1,SFXN5,PAXBP1,MAN2A2,MAP6,MBD1,ADAM11,MITF,ADAM22,SAMD14,NBL1,CCDC13,NFYA,CNOT4,NOVA2,SETD4,CDK18,PDE1B,GNG2,OLA1,PKD1,KCTD15,SH3KBP1,POLR2F,FSD1,VSTM2L,RASGEF1B,MAPK9,GRAMD1C,HYDIN,CNNM2,WDR25,ZSCAN32,CASTOR1,ZSCAN2,NWD1,ZNF493,RDX,CRTAC1,GTDC1,UBR7,RGS4,PNMA8A,KIRREL1,CCDC25,SNX22,EPHA10,GLDN,ADAL,KCNIP3,CCDC112,S100B,HES6,PEAR1,MYO18A,HKDC1,DHX30,KANSL3,SEPHS1,SLC8A1,SLC11A1,RCOR3,LIMCH1,TRERF1,NMNAT2,CLSTN2,ZC4H2,SSPO,MPRIP,ZSCAN29,DIP2A,KANK1,SYN1,TACC1,ALG1,ADGRL3,AGTPBP1,SMG6,NEU4,KIAA0930,TRIM2,CYB561A3,ZMAT3,ARL10,PRRT1,CSMD1,KAT6B,CDK20,NPL,RGMB,ZNF346,METTL3,CLIP2,CLDND1,ZNF70,ZNF74,LYPD6,MEIS3,INTS3,MAP3K12,NT5M,PRDM8,GAL3ST3,ITM2C,PCBP4,AP3B2,ST8SIA2" MicroRNA hsa-miR-2116:mirSVR_highEffct hsa-miR-2116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.46E-69 2.49E-65 2.68E-68 2.46E-67 192 1178 "CLK4,GALNT13,PTCHD1,OLMALINC,HECW2,AGT,SORCS2,OSBPL8,ADGRF5,C1QTNF3,ALCAM,UNC79,ZFAT,OGT,MAP4K3,PDE8B,ZBTB10,NCOA1,EIF4G3,DPY19L3,BACH1,ARHGEF7,FUBP1,SCAPER,CA8,THSD7A,KALRN,RUNX1T1,ZNF501,SOCS6,HECTD1,IQCK,ABI3BP,MYRIP,NECTIN3,CPS1,PREPL,RBM39,AKAP12,HAPLN1,GDA,OSBPL3,GPRASP1,GAPVD1,RIPOR2,HDAC4,LONRF1,MATR3,DNAL1,JAKMIP2,SPOCK3,USP3,DPYSL2,PDCD6IP,GOLT1B,EDNRA,TMTC1,FRY,OPTN,PHF20L1,KMT5B,PLEKHA1,MRNIP,PAN3,DCTN4,ZNF549,EXTL2,CLVS1,TAOK3,CEP78,FGF14,POLK,IP6K2,NELFCD,C2orf88,EFCAB2,PDLIM5,USP21,AP4B1,FYB1,ZMAT1,IP6K3,ZNF559,GCNT2,PCDH17,GHR,NTNG2,COPS8,TOX3,ZNF782,GPD2,STON1,ATP2B1-AS1,GRIA2,RASSF8,PADI2,IL12A,NME9,KIFC3,IPO5,NCOA7,MARK1,MBNL1,TM6SF1,MEF2C,MEST,MITF,AFDN,NCAM2,NF1,NFE2L2,DNHD1,NPTX2,SLC11A2,TREM2,GLIPR1L2,PCSK5,PFKFB2,FAM98B,PIK3C2A,FAM216A,PCDH18,MTRF1L,TRHDE,MINDY2,GRAMD1C,SAMD9,ANKHD1,ELOVL2,PTPRG,PTPRO,C1orf109,ZSCAN2,PPP2R3C,MARCH1,USP47,ZMAT4,TRIM68,FIGN,ROBO1,RPE,ATP8B4,LRRK2,CLIP1,SCN2B,ZFP30,KIF16B,SHC4,SEC31A,WDR37,ABLIM3,FAM214B,ZNF430,CCDC88A,SLC12A2,MTERF2,BTBD7,SNCA,SNRPN,KDM4C,PBLD,SSTR1,NECAB1,SYNE2,ARHGEF9,VPS13A,C12orf76,ADGRL3,SATB2,ZEB1,TRIM2,CLASP1,PCDHB6,GPRIN3,C9orf85,SMUG1,TRIO,TTC3,SGK3,UGT8,CCDC136,XPO1,ZNF708,MKRN3,CELF4,SMARCAD1,ZNF225,DOCK8,PHTF2,FBXO36,RNF170,MSRB3" MicroRNA hsa-miR-548s:mirSVR_highEffct hsa-miR-548s:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.68E-69 2.62E-65 2.81E-68 2.58E-67 172 948 "CLK4,ADCY5,BRAP,ESYT2,CC2D2A,TAOK1,PCDH10,ALK,DPP10,MAP4K3,PHF12,CDK13,STK33,N4BP2L1,BACH1,ADGRB3,ZNF599,CFLAR,PROM1,DST,ARHGEF7,THSD7A,PTBP2,VXN,ISPD,CBFA2T2,CCPG1,SOCS6,CHN1,MS4A7,QKI,SLC4A8,SEC31B,AKAP12,TRIM69,ABCG1,SEC24C,LRIG1,CSNK1G3,VCAN,FAM169A,UBXN2A,BOC,RIPOR2,ARHGAP24,DCAF8,TM9SF4,MATR3,SPOCK3,FAM107B,DPH1,MAMLD1,E2F5,EDIL3,PHF20L1,COQ7,SLC43A2,NSRP1,RACK1,GORAB,FGF1,POLR1B,FGF13,SUCO,JKAMP,SMC2,APOPT1,GALNT15,DISC1,GATM,GHR,TCERG1,GLI2,TNRC6A,ZNF496,CIT,GUCY1B1,MAP4K5,ZHX1,HLF,VSIG4,ACOT7,SMAP1,ZNF546,RBPJ,KCNN2,KCNN3,HECTD2,PIK3AP1,MAT2A,POC1B,MMP16,DBNL,MYO9A,RTL5,NUCB2,PAX6,PCSK5,PDCD2,PDE4D,SLC10A4,GPR85,XRN1,FAM216A,PMP22,TRHDE,EPB41L4B,PPP2R5E,KANSL1,MAPK9,BDNF-AS,TMEM260,STK32A,PTPRB,C1orf109,PTX3,ZNF615,CEP97,UBR7,KIF7,RIC8B,NUDT11,ROBO2,MRAP2,ZC3H14,CLIP1,SATB1,PRCD,TNFRSF19,FERMT1,FNDC3A,NLGN1,ANKRD6,NUBPL,ABLIM3,PPP4R3A,ATF7IP,RCOR3,KDM4B,SPATA7,SP4,ZNF423,ZC3H13,ERBIN,CEP68,DIP2A,PLCB1,ZEB1,PCDHB10,PCDHB3,USP32P1,FRYL,SIK3,FAM200B,DICER1-AS1,C18orf54,ACTR6,FAM124A,RIMBP2,ZNF346,SMUG1,AMACR,PPIL6,TSC1,UBE3A,ZIC1,ZNF24,ZSCAN26,PRDM8,KAT6A,JMJD1C,RNF146" MicroRNA hsa-miR-130b*:mirSVR_highEffct hsa-miR-130b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.11E-69 2.86E-65 3.06E-68 2.82E-67 218 1502 "CLK4,XKR4,KLHL32,GALNT13,BEND6,INTS2,CASKIN1,AK2,SMIM17,CDC42BPA,ANK2,PPFIA3,PPP4R4,EIF4G3,STX16,BID,SYNJ1,CACNA1G,GPC2,RAB29,IL33,CA8,KALRN,CAST,CBLN1,CBR1,LRRFIP1,CHN2,B4GALT6,FAM19A5,ARHGEF6,AKAP7,ARMC8,AKAP6,C2CD2,SH2B1,HAPLN1,CRY2,CLIP3,SNCAIP,LRIG1,ARHGEF10,SIPA1L1,PLXNA4,DZIP3,RIMS2,KATNAL2,TCAF1,RIPOR2,CENPL,MAML1,BRINP1,ARMCX4,MYEF2,LYPD1,ZC3H11A,GSDME,DDX46,ALKBH8,RHOBTB1,WDR20,CHRDL1,RAB39B,DNM1,NYAP1,PDCD6IP,ARRDC4,DTNA,DNM1L,EDN1,EDNRB,FCF1,CNNM1,FAM13A,KMT5B,AASS,PLEKHA1,PCOLCE2,DCTN4,EMX2,EPB41L2,RABEPK,CEP85L,REEP2,CLVS1,FAM198B,RPS6KC1,FCGR1A,FCGRT,OLFM1,HPCAL4,AGAP3,ATP13A4,FLT1,TRMO,STAMBP,TPK1,AP4B1,OGA,GAD1,FAM120B,ZNF559,DISC1,LYVE1,STARD3,GPD2,GRB10,PLCD4,RNF165,LINGO1,RNFT2,SYNPO,HMGCL,SMAP1,LRRCC1,KCNB1,KCNN2,CREG2,KTN1,NCOA7,MBD1,SRSF12,MEST,PPM1L,MITF,COL28A1,ZNF92,ZNF862,NF1,NOVA1,DNHD1,NPTX1,SMIM11A,GLIPR1L2,DPY19L2P2,PCDH9,PDE3A,FAM218A,RETREG1,PLCL1,MTRF1L,PDZRN4,SH3KBP1,PRKACB,MAPK9,BCAS3,VPS13C,WBP1L,ANKHD1,BDNF-AS,PTPRE,PTX3,TTC13,RBBP6,RDX,GTDC1,ZFHX4,CCDC82,ALG9,CARF,RORB,ELP2,CCDC102B,RPL15,ABCA11P,ST6GALNAC6,NCBP3,GALNT10,COPZ1,SH3GL3,CPEB3,FBXO11,FNDC3A,SLA,SEPHS1,ARHGEF40,NAPB,CDK5RAP2,ANKRD36,LIMCH1,SPP1,LMO3,PBLD,LARP4,ARHGEF9,ANKRD28,FAM208A,TCEA1,SIN3B,ZEB1,PUM2,FAM200B,TMEM9,TLR4,NPL,SYNPO2,PDSS1,TRPS1,PPIL6,SSBP2,TOM1L2,VSNL1,P2RY12,XRCC4,PCDH20,ZIC1,NDRG4,ZSCAN26,DPYSL5,EMSY,NAV3,PPP1R3F,KCNAB1,FIP1L1,EPM2A,HRASLS,FBXO36,CASC15" MicroRNA hsa-miR-374b:PITA hsa-miR-374b:PITA_TOP PITA 6.15E-69 3.44E-65 3.68E-68 3.39E-67 156 778 "ABR,ACTN1,OSBPL8,ARHGAP20,FAM135A,LRCH2,MAP4K3,APC,GAS7,ZBTB10,NCOA1,NUMB,TMEM108,ATP1A1,ATP2B2,ARHGEF7,LDLRAD4,NOG,NUMBL,CNOT8,HECTD1,AKAP7,AKAP6,HAPLN1,PHACTR3,FAM131B,BOC,ZFYVE16,MFAP3L,RUSC2,RAB39B,DMD,RCAN1,MAMLD1,ABCC5,EDIL3,SEMA3D,YAF2,MBNL2,EIF4G1,EIF4G2,TENM1,EPB41L2,EYA1,MRVI1,NRN1,CLVS1,ACSL4,MED12L,FGF13,UBE2E3,MEX3B,PDLIM5,GABRG2,MSTN,AHDC1,PCDH17,PPARGC1A,TCERG1,SPIN1,TNRC6A,GPD2,STON1,STMN2,FAM19A2,FRMD3,BACH2,MIER3,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,ZIC5,RBPJ,SLC6A17,KTN1,MAP2,MBNL1,LRP1B,MEIS1,AFF1,NFE2L2,NFIX,NOVA1,NPTX2,KSR2,OCRL,PDE4B,PDE4D,PDPK1,PIK3C2A,ZNF655,MINDY2,PPP2R2C,PRKAB2,GDPD1,SNRK,OXR1,RGS4,PRIMA1,SETD5,ALG9,RORB,HUNK,SATB1,SCN2B,FNIP1,PEAR1,CPEB3,NLGN1,SLC8A1,CPEB4,LMBRD1,MYO16,PDZD2,SOX11,SP4,ZNF423,CDK19,RBM26,POGZ,PRRC2C,SYP,SYT1,ANKRD28,TACC1,ANKRD12,FBXW11,ATMIN,TCF4,TRIM2,TCF12,SYNE1,PUM2,RIMBP2,CSMD1,TNS1,UBE2H,UBE3A,WIPF1,ZNF711,ZBTB38,SMARCAD1,CADM2,RNF103,PPP1R3F,RGS7BP,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,JMJD1C,FRMD6,SOCS4,ST8SIA2" MicroRNA hsa-miR-374a:PITA hsa-miR-374a:PITA_TOP PITA 6.15E-69 3.44E-65 3.68E-68 3.39E-67 156 778 "ABR,ACTN1,OSBPL8,ARHGAP20,FAM135A,LRCH2,MAP4K3,APC,GAS7,ZBTB10,NCOA1,NUMB,TMEM108,ATP1A1,ATP2B2,ARHGEF7,LDLRAD4,NOG,NUMBL,CNOT8,HECTD1,AKAP7,AKAP6,HAPLN1,PHACTR3,FAM131B,BOC,ZFYVE16,MFAP3L,RUSC2,RAB39B,DMD,RCAN1,MAMLD1,ABCC5,EDIL3,SEMA3D,YAF2,MBNL2,EIF4G1,EIF4G2,TENM1,EPB41L2,EYA1,MRVI1,NRN1,CLVS1,ACSL4,MED12L,FGF13,UBE2E3,MEX3B,PDLIM5,GABRG2,MSTN,AHDC1,PCDH17,PPARGC1A,TCERG1,SPIN1,TNRC6A,GPD2,STON1,STMN2,FAM19A2,FRMD3,BACH2,MIER3,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,ZIC5,RBPJ,SLC6A17,KTN1,MAP2,MBNL1,LRP1B,MEIS1,AFF1,NFE2L2,NFIX,NOVA1,NPTX2,KSR2,OCRL,PDE4B,PDE4D,PDPK1,PIK3C2A,ZNF655,MINDY2,PPP2R2C,PRKAB2,GDPD1,SNRK,OXR1,RGS4,PRIMA1,SETD5,ALG9,RORB,HUNK,SATB1,SCN2B,FNIP1,PEAR1,CPEB3,NLGN1,SLC8A1,CPEB4,LMBRD1,MYO16,PDZD2,SOX11,SP4,ZNF423,CDK19,RBM26,POGZ,PRRC2C,SYP,SYT1,ANKRD28,TACC1,ANKRD12,FBXW11,ATMIN,TCF4,TRIM2,TCF12,SYNE1,PUM2,RIMBP2,CSMD1,TNS1,UBE2H,UBE3A,WIPF1,ZNF711,ZBTB38,SMARCAD1,CADM2,RNF103,PPP1R3F,RGS7BP,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,JMJD1C,FRMD6,SOCS4,ST8SIA2" MicroRNA hsa-miR-200c*:mirSVR_lowEffct hsa-miR-200c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.47E-69 3.62E-65 3.87E-68 3.56E-67 202 1302 "NCKAP5,KLHL32,GALNT16,PLEKHH1,AP2A2,OSBPL8,SEMA6A,ALCAM,AMPH,CDC14B,TMEFF1,ARNTL,STK33,NUMB,ATP1B3,SLC2A11,ADAM23,BACH1,LINC00847,BBS2,MPDZ,HCN2,BMP7,DST,SYNJ1,ARHGEF7,CASTOR3,CACNA1G,KALRN,PTBP2,VXN,CAST,METTL6,SYNGR3,DGKI,LRRFIP1,LOC730101,MAGI1,CCPG1,SRSF11,QKI,MAP4K4,CNTN1,FAM149A,COX4I1,AHCTF1,FAM171B,RBM39,GDA,CLIP3,CS,PUM1,DNAL1,TIAM2,RUSC2,GUCD1,FAM107B,CHRDL1,DLX1,DMD,USP3,CPEB2,ECM2,FARSB,EBF1,EDNRB,EIF5,RGS17,TUBD1,STX2,SRRM1,ZNF549,ARMCX1,CLVS1,ST3GAL6,PRMT5,FER,GTF2IRD2,FGF12,FGF13,C2orf88,EFCAB2,WDR83,APOPT1,FAM49B,NSG1,GABRG1,GAD1,TMEM8B,KIAA1841,MSTN,COPS8,DBF4,GLI2,CBX1,ADGRA3,GRIA2,SPACA9,GRM8,CIT,GUCY1A1,GUCY1B1,IRAK3,IDH3A,IL6ST,ITGAM,LAMP2,LIFR,SYTL4,MEIS2,POC1B,AFF1,LYRM9,ZC3H12B,NF1,ALDH1L2,NOVA1,NTRK2,IGSF11,OXTR,PCDH9,PCSK1,PCSK5,PDE4B,FAM98B,FAM216A,JAKMIP1,STRN3,IRX1,PPM1B,RASGEF1B,PRKCB,PTN,TMEM260,PTX3,CEP97,ACSS3,FAT4,KHDRBS2,GTDC1,NUDT11,ZFHX4,GSTCD,CCDC102B,RPE,SEMA6D,SGK1,ASAP3,FBXO11,SEC31A,SLC12A2,LGI3,SLC22A4,ZKSCAN3,ZFP1,LMBRD1,FAM126B,ATP10B,PBLD,SSTR2,NKAIN2,KANK1,SULF2,SYNE2,ADAMTS17,CAMTA1,TAF9,TCF4,KIAA0930,TCF12,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,SLC44A1,THRA,TPM1,ZNF346,EIF4ENIF1,FLRT2,PLEKHH2,WRN,PCDH20,ZBTB14,MICU3,LYPD6,CELF4,REEP1,FSTL5,PRTFDC1,RNF103,HPS4,FIP1L1,FBXO36,JMJD1C,RNF170,NETO1" MicroRNA hsa-miR-520a-3p:mirSVR_highEffct hsa-miR-520a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.63E-69 3.71E-65 3.96E-68 3.64E-67 197 1241 "KIAA1211,PTCHD1,MTUS1,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,RGS20,STK33,STX16,DPY19L3,BACH1,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,CA12,CALB2,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,HECTD1,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,DNAJB6,DNM1L,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,TENM1,PLEKHA1,C3orf18,DCTN4,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,FYB1,MEGF11,IGSF5,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPR34,PCLO,ARHGAP36,SMAP1,MSL1,IDH3B,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,LAYN,MYO9A,NACA,NELL2,NF1,NRCAM,OCRL,OGG1,PCDH9,PDCD2,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,DRAM2,PRKACB,MAPK9,GRAMD1C,MASP1,SNRK,TMEM260,TTC13,CEP97,FAT4,ENOX1,OXR1,RDX,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,MCMBP,RPS20,SHC4,FBXO11,FNDC3A,WDR37,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,SYNE2,DNAJC9,CAMTA1,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PPIL6,ZNF709,VLDLR,VSNL1,LYPD6,LAMP5,CADM2,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-3187:mirSVR_lowEffct hsa-miR-3187:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.01E-69 3.92E-65 4.18E-68 3.84E-67 200 1278 "KCNH8,SYN3,NCKAP5,NDRG3,TMEM132B,ADD2,PLEKHH1,BEND6,RTL9,C1QTNF3,ALCAM,CARNS1,TRMT9B,AMPD2,DPP10,APBB2,PPFIA3,LINC00173,ALDH7A1,N4BP2L1,BCHE,CA8,CAPN3,RHBDL1,SPAG9,CBR1,CLDN10,CERS5,CCNH,CD86,MAGI1,CCPG1,ARHGAP22,EPS15L1,NRXN3,PLAA,MAP4K4,PCYT1B,ARMC8,AKAP5,ABI3BP,SNCAIP,CSNK1G3,PDE4DIP,DZIP3,PPP1R16B,KIAA0040,EARS2,TBC1D5,MATR3,IP6K1,ARMCX4,ARMCX2,DGCR5,KIAA0319,CDON,CPEB2,DTNB,MAMLD1,DNAJB6,DNM1L,CNNM1,TMTC1,FAM13A,EIF5,LRRC17,RABEPK,NCALD,DNAJC27,REEP2,FCGRT,FDFT1,FHL1,MEX3B,HPCAL4,IP6K2,ABLIM2,TVP23A,HRASLS5,SIGLEC8,GATM,ADAM28,RAB30,GNAO1,STMN2,RNF165,KAT7,RNFT2,MAP4K5,ATOH8,AGBL5,SCIN,INSM1,LAMP2,CAMK2N2,STMN1,LIFR,LMO2,SYTL4,HECTD2,MAN2A2,MAPT,AFF1,MMP16,GIT1,DBNL,COMMD5,RTL5,ZNF862,P2RY13,NPR2,OPA1,GPR137C,PCDH9,PDE1C,PDE1B,PDPK1,GPR173,GNG2,FXYD1,TRHDE,STRN3,ING3,POU6F1,PRKAB2,FITM2,DIRAS2,PRPH,RELN,DEF8,CNTLN,BDNF-AS,PTK2,PTPRE,PTPRG,PTPRO,PTX3,NKAIN1,ZNF615,TUG1,PPP2R3C,USP47,ZNF793,NWD1,MORC4,PBRM1,CCDC82,ROBO1,ROBO2,MRAP2,NEK11,FBXW7,KIAA0895L,ATAT1,KCNIP3,CLIP1,RMI1,SATB1,RASA3,SH3GL3,PPM1E,FBXO11,FNDC3A,DZIP1,ABLIM3,COA1,SMARCD3,FAIM2,MYO16,PDZD2,ZSWIM8,KDM4C,CEP68,KANK1,KLHL7,PRRC2C,SIN3B,DMXL2,TPCN2,SYNE1,PCDHB10,PCDHB3,FRYL,BHLHB9,ERCC6L2,RIMBP2,ZNF346,ELP5,RUSC1,TTC3,LMF1,RICTOR,ZNF70,ZFAND5,EMSY,GDPD5,DNAH10,SOCS4,LAS1L,FAM198A" MicroRNA hsa-miR-708*:mirSVR_highEffct hsa-miR-708*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.82E-69 4.38E-65 4.66E-68 4.29E-67 191 1170 "RALGAPA1,CLK4,PWWP2A,AP2A2,ZNF608,RTL9,HACE1,NME5,TAOK1,SPOP,UNC79,FAM135A,ZNF687,LRCH2,SHROOM2,CDK13,RNF182,ATP6V0A1,ADAM23,SEC11C,DST,CA8,CAMK2A,CAST,CLDN10,RGN,CDH2,SRSF11,SOCS6,PLAA,MAP4K4,RCHY1,AHCTF1,FAM171B,NCOR1,SIPA1L1,UBXN2A,ZSCAN23,DGKB,TMEM170A,SCRN1,DDX46,RHOBTB1,SV2B,CHRDL1,DPP6,RCAN1,DTNA,DTNB,DNAJB6,EDIL3,FCF1,FSD1L,FAM13A,PHF20L1,PLEKHA1,C3orf18,C8orf37,EPB41,ETV1,RASL12,EZH1,CEP78,FGF14,SUCO,MEX3B,FOXF2,PCYOX1,FOXO3,SMC2,KHDRBS3,STAU2,OGA,ZMAT1,MEGF10,GABBR1,GAD1,RAPGEF6,DISC1,SULT1C4,PPARGC1A,DBF4,HTATSF1,MAP7D2,RAB40B,GNAO1,GPD2,FUT10,GRIA2,PRDM5,PSIP1,BACH2,HMGCR,HNF4G,SHISA6,GAREM2,JAK2,KCNJ16,SYTL4,NCOA7,SMAD9,MARK1,MAT2A,MATN3,MBNL1,MEIS1,AFDN,MXI1,P2RY13,CHAMP1,P2RY1,GLIPR1L2,PRIMPOL,PDZRN4,STRN3,PSAT1,ING3,EPB41L4B,PILRA,PRKACB,MAPK10,HYDIN,PRPH,VPS13C,QRICH1,MTMR10,PTPRO,USP47,SH3TC2,NWD1,OXR1,GTDC1,FIGN,RFX3,PBRM1,ZFHX4,C12orf49,CARF,CCDC25,FBXW7,SPIN3,ATP8B4,TRAPPC13,RMI1,SEMA6D,HSPA4L,CPEB3,ST6GAL1,EPN2,KANSL3,CDK5RAP3,SLC9A5,ZFP1,DMRTC1,SNAP25,RBM34,NMNAT2,SPP1,CLASP2,ZC4H2,LARP4,SS18,ERBIN,STAU1,CEP68,TTBK2,DIP2A,VPS13A,SYT1,MTCL1,ZEB1,RPGRIP1L,HIF3A,AKTIP,BHLHB9,ERCC6L2,BEX4,NEIL2,STXBP4,TSC1,SGK3,WIPF1,ZNF708,TRIM9,CADM2,RNF103,PLSCR4,HNRNPA3,RNF170,KLHDC1,IFT88" MicroRNA hsa-miR-675*:mirSVR_lowEffct hsa-miR-675*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.76E-69 4.90E-65 5.21E-68 4.80E-67 185 1100 "KDM5D,GALNT16,HACE1,TAOK1,SMIM17,ALCAM,EP400,MAP4K3,PHF12,APBB2,SHROOM2,PPP4R4,NCOA1,EIF4G3,ADGRB2,C5,CALB1,KALRN,ISPD,CD86,CD38,HECTD1,PCYT1B,AHCTF1,GDA,ABCG1,SNCAIP,PDE4DIP,PLCXD3,KIAA0408,ARHGAP24,EARS2,ZNF337,LIN54,PABPC5,MYEF2,WDR20,DMD,DNAH9,SLC12A6,CASP8AP2,DTNA,AASDH,ANKRD46,MBNL2,EIF4G2,PLEKHA1,EMX2,RABEPK,SRRM1,FCGR1A,CEP78,FCGR3A,SEC24B,FGFR3,POLK,SCARA3,SEMA4D,FLT1,PSD2,SLC37A3,PDLIM5,ATP6V1H,CHL1,DISC1,LRRC37A6P,ALDH1L1,MSTN,CYP46A1,TOX3,KIAA1958,KDM2B,WDFY3-AS2,GPD2,GRM8,BTN2A1,FAM19A2,SLC2A6,MAP4K5,UBE2QL1,ZHX1,GABARAPL2,ZDHHC15,ZNF546,INPP5B,INSM1,SLC35G1,KCND2,STXBP5,HECTD2,PIK3AP1,AQP11,MATN3,MEF2C,KCTD6,MGAT3,MN1,SAMD5,MYCN,MYO9A,BEX5,NEK1,NF1,NPTX2,NTRK3,OPA1,LOC100128398,P2RX7,CNTN3,ETFRF1,NALCN,PIK3C2A,ZNF655,PLIN1,STRN3,LRP12,EXOSC10,TATDN3,NKAIN4,RASGEF1B,HYDIN,MASP1,BCAS3,QRICH1,ANKHD1,PTPRB,PTPRD,PTPRE,PTPRG,RASGRF1,SLC25A36,ROBO1,ROBO2,PTGR2,CLIP1,RYR3,NCBP3,CCDC112,SEMA6D,GALNT10,SUPT20H,SH3BGR,FNDC3A,FHOD3,R3HDM2,DZIP1,WDR37,SLC6A11,SLC12A2,LGI3,SLC22A4,MAPKBP1,CABCOCO1,ZNF415,PDZRN3,ZSWIM8,MYCBP2,RBM26,LHPP,COBL,SYNE1,PCDHB7,HIF3A,BHLHB9,TMPO,SSBP2,TUBB1,USP1,VLDLR,VSNL1,XRCC4,PCDH20,ZNF24,FSTL5,ANKS1B,EMSY,CADM2,RNF103,PDSS2,RGS7BP,DNAH10,FZD3,JMJD1C,RNF170,MSRB3" MicroRNA hsa-miR-582-3p:mirSVR_highEffct hsa-miR-582-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-68 6.39E-65 6.78E-68 6.24E-67 175 987 "NCKAP5,KDM5D,RTL9,OSBPL6,C1QTNF3,PCDH10,EP400,LCORL,PARG,CASK,TMEFF1,TMEM108,ATP1B3,N4BP2L1,DPY19L3,LINC00847,SEC11C,ARHGEF7,PTBP2,SLC25A14,NFS1,SEPT7,FAM19A5,AKAP7,IQCK,GAL3ST1,COX4I1,C2CD2,HAPLN1,CRYM,SEC24C,CSNK1G3,FAM169A,UBXN2A,DOCK4,HDAC9,TCAF1,ARHGAP24,ZFYVE16,EARS2,LONRF1,KIAA0586,PABPC5,DBI,GIT2,SPATA2,ELMO1,MFAP3L,LYPD1,DDX46,ALKBH8,SACS,USP3,DOCK2,DPH1,ACOT8,E2F5,FSD1L,FAM13A,C8orf37,DCTN4,SRRM1,DNAJC27,SCML2,CEP78,ATP13A4,NBEA,ST6GALNAC3,CSPG5,STAU2,OGA,GABBR1,FAM120B,SULT1C4,WASHC2A,PCDH17,CRCP,COPS8,TNRC6A,FERMT2,GRIK4,CIT,BVES,IRAK3,ATXN2L,TNFAIP8L3,MIER3,HMGCR,HNF4G,RBPJ,ZNF678,KIF2A,HECTD2,NCOA7,SMAD1,PIK3AP1,MAP4,MARK1,MARK3,MATN2,MBD1,PPM1L,MYT1,NF1,GLIPR1L2,PDE4B,PDPK1,FAM98B,PLCL1,PDZRN4,MAPKAP1,MAPK9,GRAMD1C,HYDIN,PTPRB,C1orf109,TTC13,ZNF615,CCDC40,RAP1GDS1,ENOX1,OXR1,PBRM1,CARF,NEK11,SPIN3,MAP6D1,LRRK2,CLIP1,NCBP3,TNFRSF19,SHC4,CHD9,NLGN1,SLA,FAM81A,WDR47,CPEB4,KIF13A,SNRPN,DOP1A,NMNAT2,UHRF1BP1L,ZBTB43,PBLD,CLASP2,TROVE2,ZSCAN29,RGL1,SULF2,KLHL7,PRRC2C,GPRIN3,FRYL,BHLHB9,BEX4,R3HDM1,WBP2,TSN,SGK3,PLEKHH2,WIPF1,XPO1,ZNF23,KCNT2,ZNF138,SPIRE1,FTSJ1,SMARCAD1,DHX33,EMSY,NAV3,PHTF2,FBXO36,FAM198A" MicroRNA hsa-miR-576-3p:mirSVR_highEffct hsa-miR-576-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-68 6.64E-65 7.04E-68 6.48E-67 174 976 "NCKAP5,KLHL32,GALNT13,AXIN2,INTS2,WDR35,SMIM17,AMPH,ZFAT,LCORL,BCAS1,CDK13,ATP2A2,ATP2B2,DPY19L3,ATP6V1G2,ATP6V0A1,TTLL9,ADGRB3,BCHE,SYNJ1,SYNJ2,KALRN,SLC25A14,MTMR7,LRBA,LRRFIP1,LOC730101,CCPG1,SRSF11,PLEKHB1,TPP1,FHL5,CNR1,LETMD1,MYRIP,GDA,TRIM69,ERC2,GREB1,RIMS2,RUBCN,TCAF1,ZFYVE16,LONRF1,MYEF2,SV2B,GRIN3A,DMD,DNAH9,DPYSL2,GOLT1B,KLHL5,YAF2,EGFR,EGR3,PLEKHA1,RCAN2,CLVS1,DLC1,ZNF589,FGF12,PRKAG2,EFCAB2,MSANTD4,MTHFD2,ZNF559,DISC1,SULT1C4,PPARGC1A,BRD8,TOX3,ZNF638,TDRKH,STON1,GRIA2,DIDO1,PSIP1,ELOVL5,C9orf129,ZDHHC15,ZNF546,ZIC5,IL6ST,NME9,HECTD2,LSS,MBNL1,MID1,POC1B,MOV10,ZNF680,MSI1,ADAM22,NRBP2,DNHD1,OPA1,P2RY1,GPR137C,PCSK1,NALCN,PLCL1,PCDH18,PDZRN4,PMP22,STRN3,LRP12,ING3,EPB41L4B,TATDN3,PPP2R5E,MAPK9,GRAMD1C,SPDL1,QDPR,ZCWPW1,MSANTD2,REV3L,ZDHHC4,ATP8B4,ZNF331,FNIP1,SUPT20H,SGK1,SHC4,CHD9,FNDC3A,BTBD3,DHX30,ZNF430,CCDC88A,ANKRD36,DOP1A,PDZD2,DBNDD2,ATP10B,CLASP2,PLCB1,SYPL1,ANKRD28,TAL1,FAM208A,ADGRL3,SIN3B,TRIM2,SYNE1,DOCK9,OBSL1,ERCC6L2,BEX4,CSMD1,SYNPO2,SMUG1,ELP5,XRCC4,ZNF24,REEP1,ADAMTS9,TMEM178A,HPS4,WNK3,NELFE,RGS7BP,RTN4,UBE3B,KAT6A,FBXO36,CASC15,ADAMTSL3,JMJD1C,RNF170,FRMD6,SENP7,JPH3" MicroRNA hsa-miR-934:mirSVR_lowEffct hsa-miR-934:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.50E-68 8.39E-65 8.89E-68 8.18E-67 176 1000 "RNF157,ADD1,PLEKHH1,ESYT2,ADRA1D,ALCAM,LRCH2,CCDC146,PKP4,TMEFF1,ARNTL,SLC2A11,DOCK11,AZGP1,BACH1,CFLAR,DST,FUBP1,GYG2,PTBP2,DCLK1,ZMYM4,CHGB,CHN2,B4GALT6,NDST3,NRXN3,QKI,ZNF521,C2CD2,HAPLN1,ARHGEF10,SIPA1L1,PNPLA8,PUM1,BOC,EARS2,ZNF337,MATR3,DGKB,TMEM170A,DBI,ARMCX4,SPOCK3,MTX3,WDR20,PDCD6IP,HIPK3,SEMA3D,FRY,CELSR3,MBNL2,KMT5B,PLEKHA1,PCOLCE2,DENND4A,EYA1,CLVS1,SCML2,FDFT1,FGF14,FGFR1,SUCO,UBE2E3,FOXO3,WDR83,SMC2,FAM49B,OGA,DISC1,LRRC37A6P,SESN1,GFER,DBF4,SPIN1,RAB30,TOX3,AIFM3,POLL,LILRB4,PCLO,GRB10,RNFT2,IRAK3,PADI2,FRMD5,FRMD3,HNF4G,NEGR1,AGFG1,IRF8,MSL1,FAM95B1,RBPJ,NME9,JAK2,KCNQ3,IPO5,KTN1,PIK3AP1,MAP6,MARK3,MEIS1,AFF1,ADAM22,MSR1,ZNF92,MX1,NTRK2,NUCB2,CHAMP1,GLIPR1L2,PCDH9,PCSK5,PFKFB2,ABCB1,XRN1,GPSM2,MTRF1L,PSAT1,RASGEF1B,MAPK7,DIRAS2,BDNF-AS,PTN,PTPRE,STRC,ACSS3,ZDHHC14,FIGN,RGS12,ZFHX4,GSTCD,CCDC102B,NEK11,GLDN,MAP6D1,ABCA11P,RTN1,NCBP3,SCN7A,ZFP2,MRAS,SGK1,ZFP30,KIF16B,NLGN1,NUBPL,EPN2,SLC12A2,BTBD7,FAM126B,DOP1A,KDM4C,RBM26,SAMSN1,TTBK2,NUDT10,CAMTA1,ADGRL3,ZFP90,ZEB1,SIRT1,ITGB3BP,AKTIP,ERCC6L2,TRIO,CLHC1,LYPD6,ZFAND5,CADM2,EVI5,TIGD6,NETO1,SOCS4,FAM198A" MicroRNA hsa-miR-873:mirSVR_highEffct hsa-miR-873:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.85E-68 1.03E-64 1.09E-67 1.01E-66 175 990 "TMCC3,PLEKHH1,ZNF608,HECW2,SMIM17,FAM135A,BIN1,ZFAT,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ZFYVE28,SEC11C,BCL7A,LDHD,BMP7,ARHGEF7,AP1M1,C5,CAST,NOG,CHN2,NRXN3,ABCG2,CNGA3,IQCK,MYRIP,CNRIP1,SEC31B,CDC42BPB,HINFP,GDA,SEC24C,PDE4DIP,CTH,GPRASP1,MYADM,ZFYVE16,MATR3,ELMO1,DDX46,DMD,DNAH9,MAMLD1,E2F6,YAF2,MBNL2,RGS17,TMEM35A,PAN3,GPHN,SIRPB1,NRN1,ABCA8,ACSL4,FHL1,SYNCRIP,RGPD5,JKAMP,PRELID3A,ST6GALNAC3,OGA,GABRG2,RAPGEF6,DISC1,AHDC1,GLI2,ZNF638,GRM2,RNFT2,ZDHHC15,TCEAL6,HSPA1L,IRF8,MSL1,MYLK2,IL6ST,STXBP5,KTN1,SYTL4,MATN3,MBP,KCTD6,MSR1,MYO7A,HNRNPM,NF1,NFE2L2,PCBP3,CNTN3,ETFRF1,PCSK5,SERPINI1,PLXNB1,MAGEL2,EPB41L4B,PPARA,RASGEF1B,PRKCB,GRAMD1C,DIRAS2,MASP1,CNTLN,TMEM260,ZSCAN32,PTPRG,CEP97,ENOX1,KHDRBS2,DPF2,RGS12,PBRM1,ZNF532,CARF,KIRREL1,PCMTD2,NEK11,ADAL,RPS6KA2,MEG3,FAM192A,SARS,SATB1,CSRNP3,PRCD,COPZ1,SH3BGR,SH3GL3,SHC4,NUBPL,ELMO2,LIMCH1,SNRPN,DOP1A,ZSWIM8,SPTAN1,LARP4,ELOVL4,RGL1,DIP2A,KANK1,SULF2,STXBP1,SYN2,COBL,PJA1,FAM208A,ADGRL3,SMG6,ZEB1,FRYL,MTMR14,PRRT1,CDK20,ZNF346,TRO,TRPM2,RUSC1,USP1,VLDLR,WRN,ZFP37,ZIC2,KCNT2,EML6,FTSJ1,SMARCAD1,DNALI1,RNF103,CIAPIN1,TRIM16L,PDSS2,DOCK8,ZDHHC20,NETO1" MicroRNA hsa-miR-23b*:mirSVR_lowEffct hsa-miR-23b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-68 1.20E-64 1.27E-67 1.17E-66 185 1106 "SYN3,ABHD6,SYS1,ADD2,AXIN2,ADORA2A,C1QTNF1,SRPX,MARCH4,AMPD2,PPFIA4,SUGT1P4-STRA6LP-CCDC180,EPB41L5,VAT1L,CPNE5,AQP6,ZFYVE28,CCDC74A,TMEM108,SLC4A4,SLC2A11,DPY19L3,ADGRB2,SEC11C,CFLAR,SCAPER,GYG2,RAB29,SPAG9,ZNF501,P2RX6,CBFA2T2,SEPT7,ZBED1,CACNA2D2,CFL2,C7orf61,RAB28,PLAA,MYL6B,DGCR9,SRP14-AS1,IGLON5,TOGARAM2,HAPLN1,TRIM69,CSF1,ARHGEF10,SUSD5,VAC14-AS1,CNTNAP2,KIAA0040,TM9SF4,TBC1D5,INTS1,IST1,AIF1L,DNAL1,YTHDC1,JAKMIP2,POM121,PLPPR4,MTX3,DLX1,GRIN3A,HS3ST2,ABCC5,OPTN,SUGP2,AASS,SIRPB1,EZH1,TUBB3,CEP78,FGF1,OLFM1,FGF11,TMEM164,EVL,SEMA4D,FLYWCH1,COQ5,WDR83,POMT1,DOT1L,MEGF10,GALNT15,RAPGEF6,ALDH1L1,WASHC2A,TNRC6A,ZNF782,GRIA2,SOX21,RNFT2,CPT1C,EID2B,KIAA1755,KCNN2,KIF5A,L1CAM,CAMK2N2,MAN2A2,ZFYVE27,MARK1,MEIS1,XRRA1,RTL5,NF1,DNHD1,NTRK2,OGG1,TMIE,KCTD15,JAKMIP1,STRN3,LRP12,MINDY2,PKIA,PRKCB,MAPK7,HYDIN,PTPRD,PTPRH,TMEM231,USP47,ENOX1,RFX2,UBR7,ZNF532,GSTCD,CCDC102B,EPHA10,SPIN3,MEG3,ABCA11P,HSD11B1L,ATAT1,S100B,ATXN2,TNFRSF19,HKDC1,AMBRA1,NLGN1,SLA,CCDC88A,CPEB4,IFT122,TEX2,ZNF423,SPART,SSTR1,ZC4H2,ZSCAN29,NSFL1C,SYP,CUX2,ZEB1,NAT16,PCDHB9,TNS2,FRYL,DICER1-AS1,GPR161,PRRT1,R3HDM1,C9orf85,DOK6,RGMB,RUSC1,TSC1,HSPBP1,EIF4ENIF1,OSBP2,WIPF1,TRIM9,NDRG4,ZBTB38,URM1,TRIM16L,PARP11,MARCH8,KAT6A,ADAMTS10,LAS1L" MicroRNA hsa-miR-2117:mirSVR_highEffct hsa-miR-2117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-68 1.32E-64 1.39E-67 1.28E-66 188 1142 "KLHL32,PWWP2A,AP2A2,INTS2,HECW2,OSBPL1A,UNC79,PKP4,PPFIA3,ATP2A2,TTLL9,MPDZ,SEC11C,BMPR1B,JAZF1,CA4,DDR1,RUNX1T1,USP6,MTMR7,P2RX6,SEPT7,NOG,TAOK2,CPNE6,PLAA,PPT2,MAP4K4,NCOR1,GDA,SNCAIP,OSBPL3,SIPA1L1,PDE4DIP,PLXNA4,UBXN2A,GPRASP1,GIT2,JAKMIP2,SPOCK3,SGSM2,RAB39B,DMD,USP3,CPEB2,DPH1,ECM2,E2F5,EBF1,YAF2,FAM13A,PHF20L1,EGFR,KMT5B,AASS,MRNIP,CALCRL,COQ7,SRRM1,MRPL37,NRN1,CLVS1,RPS6KC1,GORAB,SLC9B2,FGF13,SMC2,HVCN1,STAMBP,MSANTD4,AP4B1,SDCBP2,IQGAP2,KIAA1841,TUBGCP4,TUBA8,PPARGC1A,NTNG2,MSL3,ZNF638,CCDC184,MCHR1,PLCD4,ATE1,CIT,FAM19A2,LINGO1,PSIP1,GABARAPL2,SMAP1,LRRCC1,SCIN,ITPKB,LAMP2,STMN1,PAXBP1,NCOA7,MAP6,MAT2A,MEF2C,MEIS1,MEIS2,MITF,NF1,DNHD1,NPTX1,SLC11A2,NRCAM,TREM2,PDE4B,PDE4D,PDE1B,PDPK1,CYTL1,ZNF655,PLCL1,JAKMIP1,PDZRN4,SCHIP1,PPP1R1A,PRKACB,HYDIN,MASP1,CNTLN,TMEM260,PTPRB,PTPRN,PPP2R3C,PBRM1,RNASEL,CARF,RORB,RPL15,ATP8B4,ABCA11P,NCBP3,ZNF331,FAM192A,SEMA6D,SH3BGR,SH3GL3,CPEB3,MYO18A,HKDC1,NLGN1,PPP4R3A,FAM214B,SLC8A1,SLC12A2,ANKRD36,KIF13A,GLT8D1,SPP1,ZC3H13,NFASC,TROVE2,LARP4,RGL1,VPS13A,MLST8,KLHL4,SATB2,TCF12,TEK,FAM200B,ERCC6L2,ANKRD20A2,CA14,ZNF610,PLEKHH2,BCL2L13,MTCH1,VLDLR,ZNF711,MKRN3,ZNF138,LINC02210,PRDM10,HPS4,FIP1L1,PDSS2,RGS7BP,FZD3,ST7,PHTF2,MSRB3,IFT88,JPH3" MicroRNA hsa-miR-629*:mirSVR_highEffct hsa-miR-629*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.55E-68 1.42E-64 1.50E-67 1.38E-66 198 1263 "KCNH8,ACADM,CLK4,KLHL32,GALNT13,PWWP2A,BEND6,RTL9,KIAA1324,ADGRF5,ALCAM,FAM135A,ZNF687,CDC42BPA,DPP10,FGD2,SUGT1P4-STRA6LP-CCDC180,EPB41L5,TNRC6C,SHROOM2,NUMB,CCAR2,TMEM108,ZNF582,BACH1,CACNA1G,CACNA1A,CABP7,RUNX1T1,USP6,MTMR7,CD86,CDH2,ZMYM4,LARGE1,RCBTB2,QKI,LY86,SUMF2,LETMD1,ZFP28,HAPLN1,RGS6,ARHGEF10,SUSD5,PDE4DIP,RIMS2,USP6NL,KATNAL2,LONRF1,ARMCX4,SPATA2,FBXL5,HS3ST2,DMTF1,EBF1,EDN1,KLHL5,FAM13A,PHF20L1,EGFR,MBNL2,EIF5,COPS4,ELN,EPHB1,RABEPK,SRRM1,DENND4A,CDKL3,ABCA8,ACSL4,FCGRT,PRKAG2,SUCO,HPCAL4,SEC23B,ATP13A4,FLT1,C2orf88,SPECC1,ATP6V1H,CELF1,ABLIM2,OGA,GABRB3,RAPGEF6,ERAP1,ZNF559,NEU3,AHDC1,LYVE1,ZNF638,ADAMTS13,PSIP1,RASSF8,USP51,NEGR1,ZIC5,INSM1,CREG2,IPO5,STMN1,SMAD1,PIK3AP1,MBNL1,MEIS1,SRSF12,AFDN,ZNF680,COL28A1,LYRM9,MYO9A,NEFM,NEFH,CNOT4,NRCAM,OXTR,PCSK1,GNG2,NLGN3,ZNF655,RETREG1,XRN1,FAM216A,ZNF426,PPM1B,PRKACB,DCHS2,VPS13C,LAMA1,WDR25,PTK2,EML5,PTPRH,ZNF844,CEP97,RET,RGS3,EXD2,CARF,ROBO2,ZC3H14,ATP8B4,ABCA11P,ZNF331,ATXN7,SCP2,ZFP2,CASC3,COPZ1,ZFP30,FAM102A,ST6GAL1,CNKSR2,SLA,SIRT2,SLC9A5,SLC14A1,SNRPN,SOX3,ZSWIM8,ERC1,PEG10,RBM26,SSTR2,TTBK2,SYPL1,ANKRD12,FAM208A,KLHL4,WSCD1,SATB2,ZEB1,TCF12,NAT16,FRYL,FAM200B,GPR161,AKTIP,TIMP4,TLR4,TMPO,TPM1,NPL,TRPS1,DCBLD1,UBE3A,GORASP1,OSBP2,ZNF781,LGI4,ZNF711,ZNF708,ZNF70,CELF4,FIP1L1,AMN1" MicroRNA hsa-miR-107:mirSVR_highEffct hsa-miR-107:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.73E-68 1.53E-64 1.61E-67 1.48E-66 188 1143 "RALGAPA1,DGCR6,ABCF1,CLK4,NCKAP5,GALNT13,AXIN2,AP2A2,KIAA1324,AK2,SRPX,BBOX1,OGT,SUGT1P4-STRA6LP-CCDC180,BCAS1,LGR5,CASK,SPTBN4,PLA2G4C,MARCH3,ZBTB10,ATP2A2,ZNF582,MPDZ,NRP2,CFLAR,SYNJ1,CACNA2D1,THSD7A,KALRN,PTBP2,RUNX1T1,NDST3,CLCN3,C4orf33,QKI,SULT4A1,ARMC8,LETMD1,ABI3BP,ZFP28,CLOCK,CREM,CSF1R,VCAN,PPP6R2,GPRASP1,ARHGAP24,ZFYVE16,LONRF1,GIT2,YTHDC1,JAKMIP2,DDX46,RCAN1,DTNA,FAM78B,EBF1,TSPAN5,FCF1,YAF2,PHF20L1,MBNL2,EIF5,PLEKHA1,CEP85L,CORO2B,FCGR1A,ZNF589,OLFM1,FGF12,RGPD5,ATP13A4,NSG1,STAU2,GABRG2,RAPGEF6,DISC1,PCDH17,PPARGC1A,TOX3,TNRC6A,HTATSF1,FERMT2,LNX1,ADGRA3,GPD2,GPR12,ATE1,GSTM5,KAT7,ZHX1,KNDC1,SLC35G1,KIF5A,TTYH2,STMN1,HECTD2,NCOA7,PIK3AP1,MAP4,AQP11,MBD1,MBNL1,LRP1B,MEST,ZNF680,MYCN,NF1,NOVA1,DNHD1,NTRK2,CNTN3,PCDH8,PRTG,SCHIP1,LRRN3,GDPD1,VPS13C,GDPD2,SNRK,TMEM260,PTPRD,PPP2R3C,PID1,CEP97,FAT4,TRIM68,RET,ERI2,MRPS18A,NUDT11,RNASEL,CARF,GSTCD,FBXW7,ATP8B4,LRRK2,KCNIP1,CLIP1,SALL1,SEMA6D,SCN8A,SH3BGR,KIF21A,PPM1E,CPEB3,NLGN1,ANKRD6,WDR37,FAM81A,SLC22A4,TET1,ANKRD36,CAMTA2,PRRC2C,SYNE2,PLCB1,C12orf76,ADGRL3,TBCEL,SATB2,TRIM2,RPGRIP1L,FRYL,RNF216P1,DICER1,ZFPM2,SLC44A1,TK2,RIMBP2,CSMD1,RGMB,RUNDC3B,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE2H,BCL2L13,P2RY12,ZNF711,EML6,LINC02210,ADAMTS9,PLSCR4,ADAMTSL3,RNF170" MicroRNA hsa-miR-103:mirSVR_highEffct hsa-miR-103:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.73E-68 1.53E-64 1.61E-67 1.48E-66 188 1143 "RALGAPA1,DGCR6,ABCF1,CLK4,NCKAP5,GALNT13,AXIN2,AP2A2,KIAA1324,AK2,SRPX,BBOX1,OGT,SUGT1P4-STRA6LP-CCDC180,BCAS1,LGR5,CASK,SPTBN4,PLA2G4C,MARCH3,ZBTB10,ATP2A2,ZNF582,MPDZ,NRP2,CFLAR,SYNJ1,CACNA2D1,THSD7A,KALRN,PTBP2,RUNX1T1,NDST3,CLCN3,C4orf33,QKI,SULT4A1,ARMC8,LETMD1,ABI3BP,ZFP28,CLOCK,CREM,CSF1R,VCAN,PPP6R2,GPRASP1,ARHGAP24,ZFYVE16,LONRF1,GIT2,YTHDC1,JAKMIP2,DDX46,RCAN1,DTNA,FAM78B,EBF1,TSPAN5,FCF1,YAF2,PHF20L1,MBNL2,EIF5,PLEKHA1,CEP85L,CORO2B,FCGR1A,ZNF589,OLFM1,FGF12,RGPD5,ATP13A4,NSG1,STAU2,GABRG2,RAPGEF6,DISC1,PCDH17,PPARGC1A,TOX3,TNRC6A,HTATSF1,FERMT2,LNX1,ADGRA3,GPD2,GPR12,ATE1,GSTM5,KAT7,ZHX1,KNDC1,SLC35G1,KIF5A,TTYH2,STMN1,HECTD2,NCOA7,PIK3AP1,MAP4,AQP11,MBD1,MBNL1,LRP1B,MEST,ZNF680,MYCN,NF1,NOVA1,DNHD1,NTRK2,CNTN3,PCDH8,PRTG,SCHIP1,LRRN3,GDPD1,VPS13C,GDPD2,SNRK,TMEM260,PTPRD,PPP2R3C,PID1,CEP97,FAT4,TRIM68,RET,ERI2,MRPS18A,NUDT11,RNASEL,CARF,GSTCD,FBXW7,ATP8B4,LRRK2,KCNIP1,CLIP1,SALL1,SEMA6D,SCN8A,SH3BGR,KIF21A,PPM1E,CPEB3,NLGN1,ANKRD6,WDR37,FAM81A,SLC22A4,TET1,ANKRD36,CAMTA2,PRRC2C,SYNE2,PLCB1,C12orf76,ADGRL3,TBCEL,SATB2,TRIM2,RPGRIP1L,FRYL,RNF216P1,DICER1,ZFPM2,SLC44A1,TK2,RIMBP2,CSMD1,RGMB,RUNDC3B,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE2H,BCL2L13,P2RY12,ZNF711,EML6,LINC02210,ADAMTS9,PLSCR4,ADAMTSL3,RNF170" MicroRNA hsa-miR-631:mirSVR_lowEffct hsa-miR-631:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.15E-68 1.76E-64 1.85E-67 1.71E-66 188 1144 "SYS1,GALNT16,ADD2,PWWP2A,DPY19L2P4,ZNF578,SPARCL1,CARNS1,PITPNM2,OGT,MAP4K3,MYH7B,PPFIA4,SUGT1P4-STRA6LP-CCDC180,CDK10,IGDCC4,SPTBN4,PCDHGB4,NCOA1,NUMB,ATP6V1G2,BID,PROM1,KSR1,ARHGEF7,DDR1,LURAP1,PTBP2,USP6,PLAA,DGCR9,RAB26,ZNF385A,CREM,ENTPD4,SEC24C,ERC2,CTH,GREB1,FAM131B,SEC14L5,CCDC144A,EARS2,DAPK1,MFAP3L,POM121,DLX1,RAB39B,DNM1,USP3,NR1D2,E2F5,CNNM1,HEYL,PHF20L1,EGFR,ING4,IGSF6,ZNF549,MRPL37,MRPL10,SIRPB1,KATNAL1,ZNF589,FER,FGF11,BAIAP2,PSD2,FLYWCH1,EFCAB2,TPK1,RASL10A,STAU2,GHDC,DISC1,GATM,AHDC1,CRCP,LPAR4,GRIN2C,MAN1B1,BACH2,ELOVL5,HNF4G,TCEAL6,IRF8,IDH3A,ZNF546,RBPJ,A1BG-AS1,SYTL4,MATN2,MBD1,MBNL1,ADAM11,MEF2C,KITLG,AFDN,MSI1,TAGLN3,LAYN,MYO7A,ZC3H12B,VWA2,CNOT4,NOVA2,NUCB2,DPY19L2P2,PCDHGC3,PDE1B,SLC10A4,SEMA5B,FAM218A,EPB41L4B,CEP41,MAPK9,MASP1,WBP1L,ZSCAN32,C1orf109,ZSCAN2,NKAIN1,MARCH1,CCDC40,RASGRF2,PRRT2,MRPS18A,ZFHX4,C12orf49,CARF,CCDC25,FBXW7,SGSM1,CSRNP3,SHC4,HKDC1,SLC6A11,ARHGEF40,SLC12A4,SMARCA4,INAVA,MBD5,FAIM2,DOP1A,PDZD2,ATP10B,CLASP2,ZC4H2,NKAIN2,SSPO,NSFL1C,SYT1,PDLIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,CYB561A3,AP4E1,SLC44A1,CABIN1,TP53BP1,WBP2,NR2C2,TRIO,RUSC1,TTTY15,TUBB1,PLPPR2,KLC2,ZNF154,TMEM237,LAMP5,SMARCAD1,SLC30A4,EMSY,ADAMTS9,URM1,PHTF2,PRRT4" MicroRNA hsa-miR-325:mirSVR_lowEffct hsa-miR-325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.20E-68 1.79E-64 1.88E-67 1.73E-66 184 1097 "KLHL32,MTUS1,CARNS1,LCORL,APBA2,ARHGDIA,PLA2G4C,BCHE,CFLAR,BMPR1B,BTK,CASTOR3,SGCE,IL33,CALB1,PTBP2,CBR1,CERS5,CD38,SEPT7,LRRFIP1,SRSF11,B4GALT6,NDST3,CLCN3,FAM19A5,QKI,ARHGEF6,CNTN1,PCYT1B,AKAP6,COL4A5,ABI3BP,NRG2,CNRIP1,CREM,HAPLN1,CS,APPL1,PHF14,CTH,DOCK4,RIPOR2,DAPK1,PITPNC1,SPOCK3,DMD,DYNC1I1,ARRDC4,ECM2,WDPCP,FRY,FSD1L,KMT5B,EIF1,MRVI1,FCGR1A,FDFT1,GORAB,FECH,SEC24B,FGF13,FGF14,SEMA4D,FLT1,C2orf88,NBEA,ERGIC3,TVP23A,GABRG1,GABRG2,B4GALNT1,RAPGEF6,IQGAP2,LRRC37A6P,KIAA1841,GATM,GCNT2,SULT1C4,GPR162,GGTA1P,MAP7D2,GNAL,FERMT2,WDFY3-AS2,TMEM121B,TPPP,COQ10A,AP4S1,AGBL5,LRRCC1,ITPKB,SLC35G1,MAN2A2,MAP4,MATN2,MBD1,LRP1B,MEIS1,SRSF12,AFF1,MPP2,MYT1,P2RY13,SMIM11A,NTRK2,P2RX7,GPR137C,CCSER2,PCDH18,LRP12,SH3KBP1,PPM1B,PPP2R2B,RANBP3L,RASGEF1B,PRKACB,MAPK4,MAPK9,ANKHD1,PTN,TMEM260,ZSCAN32,PTPRG,PEX2,CCDC40,ZNF793,FAT4,OXR1,MSANTD2,KLHDC8A,CARF,RORB,ABCA11P,CLIP1,SCN8A,MRAS,ARX,FBXO11,NLGN1,SLA,SLC12A2,GKAP1,RCOR3,SNRPN,DOP1A,DOK5,SP2,KDM4C,ZC3H13,RBM26,TROVE2,ZC4H2,LARP4,SYP,C12orf76,ZFP90,TRIM2,DOCK9,PHF24,PUM2,FRYL,DICER1,AP4E1,BHLHB9,RIMBP2,AMACR,FAM155A,UGT8,FLRT2,TBC1D15,RICTOR,ZNF711,MICU3,ZNF28,ELFN1,ZNF195,EMSY,PLSCR4,FAM219B,NETO1,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-596:mirSVR_lowEffct hsa-miR-596:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-68 1.80E-64 1.88E-67 1.73E-66 194 1216 "VWA5B2,KLHL32,ADCY6,ZNF608,AK2,SRPX,OGT,SMIM29,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,UPRT,USP37,MADD,IGDCC4,LINC00173,SLC2A11,ADAM15,RGS9,KSR1,SCAPER,JAZF1,CFAP410,DDR1,KALRN,SCARB1,CD38,LOC730101,LARGE1,CBARP,MS4A7,CLCN3,RAB26,AKAP5,SLC4A8,ABI3BP,IGDCC3,SNCAIP,SEC24C,OSBPL3,PHACTR3,FAM169A,ARHGEF4,DCAF4,MAML1,DGKB,SCRN1,MYEF2,C2CD2L,KLHL3,TMEM130,DMD,HS3ST2,DMTF1,DPH1,PDCD6IP,ECM2,DNAJB6,ABCC5,CNNM1,EGR3,RASA4,ELN,NCALD,SPEG,EZH1,FAM198B,ZNF589,GTF2IRD2,FGF1,TMEM164,FOXF2,WDR83,HVCN1,SDCBP2,NEURL4,TRAF3IP2,FAM120B,SIGLEC8,GGT5,RUNDC3A,TOX3,TNRC6A,GLUL,STARD3,DCLK2,ADGRA3,ZBTB49,AP4S1,LINGO1,NCKAP1L,HNMT,NEGR1,TCEAL6,EID2B,ZNF181,MYLK2,INSM1,SYTL4,NCOA7,ASPRV1,ZFYVE27,MAT2A,MBD1,COMMD5,ADAM22,MYO9A,RTL5,SLC11A2,GPR137C,CDK18,GPR173,PFKFB2,ZDHHC8,SEMA5B,FAM218A,POLG,NDUFS7,PIGG,IQSEC3,RBBP6,FIGN,KLHL11,ZNF532,KIRREL1,CCDC25,RPL15,SPIN3,ADAL,CLIP1,MAPK12,PRCD,STUM,SGK1,FAM102A,CPEB3,SHMT2,HKDC1,CNKSR2,WDR37,EPN2,WDR47,NAPB,BTBD7,TET1,OGDHL,CDK5RAP2,SMARCD3,KIF13A,BDP1,KDM3A,HECW1,PEG10,SPTB,NFASC,SEPT3,ZC3H4,PLCB1,TMEM150C,SYP,SYPL1,MLST8,ZFP90,PCDHA5,CYB561A3,ZFPM2,GPR161,SLC44A1,ZNF346,SYNPO2,TRO,NUTM2A,PPIL6,ANKRD20A2,TTTY15,UBTF,BCL2L13,LGI4,TRIM9,ZNF74,MKRN3,FSTL5,ANKS1B,DHX33,EMSY,DNALI1,NAV3,SLC17A7,PARP11,DOCK8,CASC15,FAM219B,RNF170,TTC7A" MicroRNA hsa-miR-4317:mirSVR_lowEffct hsa-miR-4317:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.26E-68 1.83E-64 1.91E-67 1.76E-66 192 1192 "ASPHD1,SYN3,NCKAP5,CCDC85A,LRFN2,SLC24A4,ZNF608,HACE1,OSBPL1A,CC2D2A,AK2,ALK,AMPD2,PKP4,APAF1,ZFYVE28,LINC00173,ATP6V0A1,AZGP1,MIR9-3HG,KSR1,CALM1,KALRN,RUNX1T1,CBFA2T2,LRBA,MAGI1,NRXN3,CNR1,AKAP6,ANKRD35,SLC4A8,TOGARAM2,MYRIP,RGS6,IPCEF1,SLITRK5,CTH,CCDC144A,BOC,DOCK4,KATNAL2,LIN54,SCRN1,BRINP1,DBN1,ARMCX4,JAKMIP2,ZNF804A,PLPPR4,SACS,WDR20,FAM107B,HS3ST2,CPEB2,AASDH,WDPCP,KMT5B,PLEKHA1,RABEPK,ERBB4,TLR7,ABCA8,SH3YL1,TBC1D16,FGFR1,FGFR3,BAIAP2,IP6K2,SYNCRIP,NOP56,ZMAT1,GABRG2,RAPGEF6,IP6K3,ZNF559,DISC1,ADAM28,GGTA1P,CRCP,ZNF638,STON1,GPR37,PCLO,CIT,GUCY1B1,IRAK3,EID2B,RBPJ,SCIN,JAK2,SLC35G1,A1BG-AS1,LMO2,HECTD2,MARK3,MAT2A,MEIS1,PPM1L,MITF,MKLN1,MMP16,N6AMT1,MYT1,NPR2,SLC11A2,SMIM11A,OGG1,PDE4B,OLA1,TMIE,GPSM2,SH3KBP1,RASGEF1B,PRPSAP2,PIGG,ANKHD1,PTK2,SPDL1,TMEM260,PTPRG,ACSM5,RIPOR1,NWD1,ENOX1,REV3L,RFX3,KCTD17,ROBO2,MRAP2,RPL15,LRRK2,SATB1,STUM,SUPT20H,RASA3,SGK1,SH3GL3,CHD9,FBXO11,FHOD3,CNKSR2,KANSL3,SEPHS1,LGI3,CPEB4,MYH15,LIMCH1,KIF13A,CMTR2,SNRPN,SP2,HECW1,ZC3H13,RBM26,NFASC,ITPRID2,ZC4H2,SS18,DIP2A,PHLDB1,SEPT3,ANKRD28,ATMIN,DMXL2,NAT16,USP32P1,DICER1,ZFPM2,TMPO,TPM2,PDSS1,NEIL2,TRO,SGK3,PLEKHH2,PLPPR2,VSNL1,CFAP298,PCDH20,ELFN1,ZNF70,LYPD6,FTSJ1,EMSY,GDPD5,TMEM178A,GAL3ST3,KCNAB1,TRAM2-AS1,NHSL1,ST8SIA2" MicroRNA hsa-miR-2114:mirSVR_lowEffct hsa-miR-2114:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.89E-68 2.18E-64 2.28E-67 2.10E-66 207 1378 "KCNH8,ASPHD1,CLK4,SYS1,GALNT16,KIAA1211,RNF150,HECW2,AK2,SEMA6A,ALCAM,PCDH10,TRMT9B,AMPD2,AMPD3,CDC42BPA,ANK2,EPB41L5,TNRC6C,AQP6,ARNTL,LINC00173,ZBTB10,NUMB,CARMIL3,BCL7A,BTK,CASTOR3,PTBP2,VXN,ISPD,CBLN1,USP6,ARHGEF1,SCARB1,DGKI,UBE2L6,RCBTB2,SLIT2,RAB28,NRXN3,TPP1,AKAP7,FAM149A,COL11A2,COX4I1,HAPLN1,CS,KIAA0408,SPOCK2,ARMCX4,MYEF2,KLHL3,DDX46,GUCD1,PARD6A,EXOG,RAB39B,DMD,NYAP1,CASP8AP2,DPP6,PDCD6IP,E2F5,E2F6,EDN1,EDNRB,HEYL,TMTC1,FAM13A,EGFR,MRO,PLEKHA1,EPB41,NCALD,SPEG,MRPL10,ADGRV1,F5,TBC1D16,ACSL4,FCGR1A,CHST15,FCGR3A,ZNF589,GTF2IRD2,OLFM1,SPSB4,RGPD5,ATP13A4,UFM1,CAMKK2,ZNF605,CELF1,ZNF274,ERAP1,GGTA1P,LYVE1,SPIN1,GPR12,CCDC184,RNF165,KAT7,RASSF8,MIER3,LRRC75A,ICA1,TJAP1,ITGAM,ITPKB,SLC35G1,KIF5A,LAMP2,AQP11,CHIC1,MEIS1,MEIS2,KITLG,PPM1L,MYO7A,NEFH,NOVA1,P2RX7,GPR173,GNG2,NALCN,PLXNB1,ING3,POLR2F,PCDHB17P,RASGEF1B,MAPK4,CNNM2,CNTLN,PTN,PTPRB,PTPRE,PTX3,ZSCAN2,TMEM231,CCDC40,FAM66C,SH3TC2,OXR1,RGS3,KCTD17,KIF7,NUDT11,RNASEL,ZFHX4,TMLHE,ELP2,SGSM1,PTGR2,ATAT1,FAM192A,S100B,ATXN7,TRA2B,CPEB3,AMBRA1,SLA,SLC2A5,FAM214B,SIRT2,SLC11A1,SLC12A2,NAPB,CPEB4,GKAP1,KDM4B,PEG10,ZBTB43,SS18,PHLDB1,NSFL1C,VPS13A,COBL,TACC1,CAMTA1,FAM208A,SIN3B,C9orf85,WBP2,SMUG1,HSPBP1,GORASP1,WIPF1,RICTOR,ZBTB14,ZNF24,ZNF28,ELFN1,ZNF45,LYPD6,ANKS1B,DHX33,SLC30A4,LINC02210,STOX2,CIAPIN1,GAL3ST3,SLC17A7,ST7,TRAM2-AS1,NETO1,GAN" MicroRNA hsa-miR-874:mirSVR_lowEffct hsa-miR-874:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-68 2.23E-64 2.33E-67 2.15E-66 216 1493 "EMILIN3,SYS1,XKR4,FMNL2,ADCY6,PTCHD1,ADRA1D,CEP126,ANK2,SUGT1P4-STRA6LP-CCDC180,APAF1,PHYHD1,CDC14B,SPTBN4,PLA2G4C,CDK13,SLC2A11,ADAM15,BCHE,RGS11,DST,MYRF,IL33,CACNA1B,CAMK2G,ARHGEF25,USP2,P2RX6,CDC25B,LARGE1,CRLF1,CHN2,EPS15L1,ABCG2,ARHGEF6,CABP1,ZFP28,SEC31B,SH2B1,AATK,SNCAIP,SEC24C,PLXNA4,SLITRK5,GREB1,PPP6R2,DCAF4,CYBB,HDAC9,IST1,SPATA2,DGCR5,GUCD1,SGSM2,FAM107B,KIF19,DYNC1I1,DOCK2,DPH1,RCAN1,CNNM1,PHF20L1,SUGP2,EGFR,EGR3,TENM1,SRPK3,ELN,C8orf37,ZNF549,SPEG,RASL12,F8,DLC1,ZNF589,FGF1,FGF11,FGF13,HPCAL4,IP6K2,COQ5,EFCAB2,WDR83,TMEM107,ZNF605,ERGIC3,AP4B1,ABLIM2,GALC,ZNF274,ERAP1,MTHFD2,GCK,RUNDC3A,CRCP,GPD2,CCDC184,MCHR1,DIDO1,RNFT2,SLC2A6,PADI2,DDX19B,VSIG4,ELOVL5,CELF5,ICA1,KIAA1755,IL12A,INPP5B,ITPKB,CDH20,GPR62,KCNH2,KCNK3,KIF5A,STXBP5,NCOA7,ZFYVE27,MBD1,LRP1B,AFDN,XRRA1,SAMD5,PTOV1,MYO7A,SFR1,NNAT,CNOT4,TBC1D25,PDE1B,PFKFB3,PFKFB4,SEMA5B,CCSER2,PKM,PLCB2,MTRF1L,PNMA3,SCHIP1,SEPT4,PPP5C,HYDIN,ZSCAN32,PTPRD,PTPRN2,CCDC40,RASGRF1,RGS12,PBRM1,LGI2,SNX22,EPHA10,BAALC,GLDN,SGSM1,MAP6D1,LRRK2,FAM161B,PRCD,TNFRSF19,GALNT10,FOXRED1,ASAP3,MYO18A,SHC4,HKDC1,LIMS2,ATF7IP,LGI3,CXXC4,CDK5RAP2,PDZD2,ZSWIM8,IZUMO4,KDM4C,DDN,CLSTN2,CAMTA2,ST5,SEPT8,ADHFE1,SULF2,NUDT10,SYN2,TAL1,ALG1,TBCEL,SMG6,ATMIN,ZEB1,ARHGAP9,TIAM1,CSMD1,ZNF346,SMUG1,TRIO,STXBP4,TRPS1,FAM155A,EIF4ENIF1,UBTF,BCL2L13,LAT2,WRN,RICTOR,GUSBP1,NDRG4,EML6,MEIS3,STOX2,ADAMTS9,CIAPIN1,NAV3,SOCS4,LAS1L" MicroRNA hsa-miR-3167:mirSVR_highEffct hsa-miR-3167:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.12E-68 2.30E-64 2.41E-67 2.22E-66 187 1134 "XKR4,TMEM132B,AXIN2,PCDH19,CC2D2A,TAOK1,SEMA6A,CARNS1,FAM135A,OGT,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PARG,APBA2,PHYHD1,LGR5,RGS20,ATP2B2,RNF182,ALDH7A1,ATP6V1G2,TTLL9,RGS9,NRP2,CFLAR,SCAPER,JAZF1,GYG2,SLC25A14,CAST,USP6,DGKI,TIGD7,QKI,AHCTF1,RTTN,AKAP12,SNCAIP,CSF1,ARHGEF10,GREB1,RIMS2,DCAF4,RUBCN,HDAC9,GAPVD1,DBN1,WDR20,DNM1L,GOLT1B,EBF1,EDN1,ANKRD46,PHF20L1,EPB41,EPHB1,CEP85L,ZNF549,NRN1,F5,FKTN,ANKFY1,TRIM16,ST6GALNAC3,AP4B1,FYB1,GALNT15,GAD1,TUBGCP4,TUBA8,SULT1C4,ARFIP1,SESN1,RUNDC3A,GLYR1,CBX1,FERMT2,CCDC184,GPR34,CNTRL,FICD,UBE2QL1,TNFAIP8L3,NEGR1,KCNN3,KIFC3,MAP4,MBNL1,MEF2C,MITF,ADAM22,NF1,VWA2,NTRK2,NUCB2,CLDN11,CNTN3,PAX6,PCDH18,PMP22,SH3KBP1,DRAM2,PPP2R5E,PRKACB,HYDIN,CNTLN,ANKHD1,ZSCAN32,PTPRE,ZNF615,CEP97,SLC25A48,NWD1,RAP1GDS1,ZNF493,KCTD17,RIC8B,CARF,CCDC102B,TCP11L1,ABCA11P,RTN1,ZNF568,SCN8A,SHC4,HKDC1,NUBPL,WDR37,FAM81A,SLC2A5,ZNF430,SEPHS1,ATF7IP,INTS9,SNRPN,KDM4B,SPART,ZNF302,NKAIN2,SS18,NXT2,ADHFE1,SULF2,PRRC2C,SYP,ANKRD28,PJA1,AGTPBP1,ZFP90,CUX2,TCF12,PCDHB4,PCDHB3,NSD1,USP32P1,RNF175,SIK3,RNF216P1,ASXL3,TMPO,FAM124A,RIMBP2,C9orf85,RGMB,SYNPO2,TTC3,ZKSCAN5,FAM155A,UBE2H,BCL2L13,ZNF781,ZNF711,ZNF708,MICU3,REEP1,EML6,EMSY,PRDM10,TRIM16L,EPM2A,FBXO36,ADAMTSL3,JMJD1C,TIGD6,KLHDC1,SOCS4" MicroRNA hsa-miR-548p:PITA hsa-miR-548p:PITA_TOP PITA 4.16E-68 2.33E-64 2.43E-67 2.23E-66 166 895 "FMNL2,GALNT16,USP31,KLHL13,PCDH19,OSBPL6,FAM135A,DPP10,APBB2,APC,GAS7,CADPS,WASF1,CACNB4,THSD7A,PTBP2,CAMK2A,CAMK2G,CBFA2T2,MAGI1,FOXN3,SOCS6,CHN2,B4GALT6,NRXN3,CLTC,QKI,HECTD1,ARMC8,COL4A5,IGDCC3,OSBPL3,APPL1,DOCK4,ARHGAP24,DCAF8,ZFYVE16,LONRF1,MAML1,IST1,YTHDC1,ELMSAN1,MYEF2,ZC3H11A,WDR20,CHRDL1,GRIN3A,CPEB2,SLC12A6,ABCC5,EDNRA,HIPK3,APH1A,MBNL2,EGR3,TENM1,PAN3,EPB41L2,GPHN,ETV1,ACSL4,SEMA4D,PSD2,CELF1,GABRB3,IQGAP2,SESN1,TOX3,RAB40B,TDRKH,CNTRL,GRIA2,FAM19A2,ADAMTS6,MAP4K5,AGFG1,HSF2,SOWAHA,IGF1,RBPJ,KCND2,STXBP5,KTN1,SMAD1,MAP2,MARK1,MBNL1,CHIC1,LRP1B,MEF2C,MEIS2,MIA2,POC1B,AFF1,MN1,SAMD5,NF1,NFIX,NRCAM,PDE3A,PDE4D,GPR85,PIK3R1,XRN1,PCDH18,STRN3,EPB41L4B,SH3KBP1,PPP3CA,VSTM2L,RELN,USP47,RBBP6,RBBP8,MSANTD2,RDX,REV3L,FIGN,ZFHX4,RMI1,CSRNP3,GALNT10,ZFP30,SH3GL3,CPEB3,CHD9,WDR47,NAPB,ELMO2,CPEB4,PDZRN3,CDK19,LMO3,ZNF621,CLASP2,SSTR1,ERBIN,SULF2,SYPL1,CAMTA1,MCF2L,FAM208A,FBXW11,TBL1X,TCF4,TRIM2,PUM2,AP4E1,TIAM1,TSC1,UBE3A,OSBP2,VGF,VSNL1,KCNT2,NDRG4,ZBTB38,ZFAND5,SMARCAD1,SLC38A1,EVI5,STOX2,SMIM8,HNRNPA3,FRMD6,CPNE4" MicroRNA hsa-miR-376a:mirSVR_highEffct hsa-miR-376a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.21E-68 2.35E-64 2.46E-67 2.26E-66 188 1146 "NCKAP5,TMEM132B,PWWP2A,PTCHD1,INTS2,NME5,OSBPL8,HFM1,PCDH10,LRCH2,ANK2,APC,LGR5,ZFYVE28,ATP2A2,ADGRB2,BARD1,PROM1,SCAPER,MTMR3,CACNA1G,CA8,SLC25A14,VXN,CH25H,RUNX1T1,MTMR7,SLC16A4,LRBA,SEPT7,CDO1,SRSF11,PPT2,QKI,ABI3BP,FAM171B,HAPLN1,ANKRD44,CSNK1G3,PDE4DIP,RIMS2,HDAC9,GAPVD1,LIN54,IP6K1,MYEF2,ALKBH8,WDR20,EXOG,DNAH9,DMTF1,DPP6,ECM2,E2F5,WDPCP,EDN1,RASGRP1,TMTC1,DCTN4,EPB41,RABEPK,SRRM1,PRMT5,POLR1B,POLK,ATP2C1,KHDRBS3,ST6GALNAC3,NSG1,MEGF11,GALNT15,ZNF559,SULT1C4,ADAM28,MALT1,TOX3,CBX1,FERMT2,WDFY3-AS2,GRIK5,CLASRP,HAS2,MIER3,HNF4G,SMAP1,ITPKB,METTL21A,KCNH2,STXBP5,LAMP2,LIG4,PAXBP1,PIK3AP1,MBD1,POC1B,MMP16,GIT1,LAYN,MYO9A,NCAM2,ALDH1L2,CNOT4,DPY19L2P2,PDE4B,SLC10A4,OLA1,FAM218A,CCSER2,NLE1,LRP12,ING3,PPP2R5E,PRKACB,CEP41,MASP1,VPS13C,ELOVL2,SPDL1,STK32A,PTPN13,ZNF615,USP47,GAL3ST4,ERI2,RGS3,SETD5,TMLHE,ROBO1,RORB,NEK11,EPHA10,ZNF671,AP1AR,SALL1,COPZ1,FERMT1,SHC4,CHD9,FBXO11,TET1,MAST1,CDK5RAP2,MYH15,RCOR3,IFT122,MBD5,MYCBP2,SPP1,KDM4C,CDK19,SPART,ITPRID2,LARP4,NKAIN2,ARHGEF9,ANKRD28,TBCEL,CUX2,PCDHB9,FAM200B,TIAM1,ASXL3,CABIN1,ELP5,TRIO,KCNE5,UGT8,VLDLR,VSNL1,WIPF1,KCNT2,CELF4,ZNF189,ANKS1B,SMARCAD1,DHX33,ZNF225,SLC30A3,RNF103,NAV3,PPP1R3F,PARP11,FZD3,PHTF2,ADAMTSL3,JMJD1C,IFT88,JPH3" MicroRNA hsa-miR-133a:mirSVR_lowEffct hsa-miR-133a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.86E-68 2.72E-64 2.83E-67 2.61E-66 188 1147 "ACADM,ABHD6,ADCY6,BEND6,ABCD2,PCDH10,FAM135A,FGD2,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PPFIA3,AQP6,CASK,ARHGDIA,ARNTL,PCDHGB4,ZBTB10,ATP2B2,RIPK1,LINC00847,DST,JAZF1,RAB29,CA8,CALM1,SPAG9,USP6,CBFA2T2,LRRFIP1,DIS3L,FAM19A5,QKI,LETMD1,BAG4,ZNF521,ABCG1,SLITRK5,RUBCN,ARHGAP24,ZNF337,DGKB,DGKG,TMEM170A,PABPC5,GIT2,HEPH,USP3,DNAJB6,CNNM1,FAM13A,PHF20L1,TNK2,ERBB2,ANKMY1,REEP2,FAM198B,FCGR3A,FGF1,FGFR1,SCARA3,IP6K2,PSD2,NOP56,CAMKK2,CELF1,STAU2,IQGAP2,TMEM8B,SIGLEC8,SESN1,GGT7,TTBK1,RAB30,ZNF638,DCLK2,GPR12,TMEM121B,STMN2,GRIA2,ADAMTS13,ZNF496,ZHX1,FRMD5,MIER3,AGBL5,SHISA6,CELF5,LRRCC1,IL6ST,JAK2,KLHL23,STXBP5,SFXN5,MARK1,CHIC1,SAMD5,MYO7A,NCAM2,NELL2,NTRK3,NUCB2,LOC100128398,P2RY1,PCDHGC3,GNG2,PFKFB3,SEMA5B,PIK3C2A,KCTD15,NLE1,PRIMPOL,LRP12,PPP2R5E,MAPK4,HYDIN,ELOVL2,CCDC40,FAM66C,RET,UBR7,LGI2,GSTCD,NEK11,EPHA10,SPIN3,GLDN,AP1AR,CASC3,RASA3,KIF21A,SH3GL3,FNDC3A,ST6GAL1,CNKSR2,PPP4R3A,ANKRD36,HECW1,ERC1,UNC5B,PEG10,RBM26,ATP10B,SSTR1,ELOVL4,SEPT8,DIP2A,STXBP1,VPS13A,SYN2,TCEA1,DMXL2,CUX2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NAT16,DOCK9,PHF24,USP32P1,GPRIN3,SIRT1,DICER1-AS1,TK2,SMUG1,TRO,STXBP4,TTC3,ZKSCAN5,WIPF1,LAT2,XPO1,ZBTB14,ZNF24,MKRN3,ZBTB38,POLR3H,ANKS1B,FIP1L1,PHTF2" MicroRNA hsa-miR-133b:mirSVR_lowEffct hsa-miR-133b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.86E-68 2.72E-64 2.83E-67 2.61E-66 188 1147 "ACADM,ABHD6,ADCY6,BEND6,ABCD2,PCDH10,FAM135A,FGD2,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PPFIA3,AQP6,CASK,ARHGDIA,ARNTL,PCDHGB4,ZBTB10,ATP2B2,RIPK1,LINC00847,DST,JAZF1,RAB29,CA8,CALM1,SPAG9,USP6,CBFA2T2,LRRFIP1,DIS3L,FAM19A5,QKI,LETMD1,BAG4,ZNF521,ABCG1,SLITRK5,RUBCN,ARHGAP24,ZNF337,DGKB,DGKG,TMEM170A,PABPC5,GIT2,HEPH,USP3,DNAJB6,CNNM1,FAM13A,PHF20L1,TNK2,ERBB2,ANKMY1,REEP2,FAM198B,FCGR3A,FGF1,FGFR1,SCARA3,IP6K2,PSD2,NOP56,CAMKK2,CELF1,STAU2,IQGAP2,TMEM8B,SIGLEC8,SESN1,GGT7,TTBK1,RAB30,ZNF638,DCLK2,GPR12,TMEM121B,STMN2,GRIA2,ADAMTS13,ZNF496,ZHX1,FRMD5,MIER3,AGBL5,SHISA6,CELF5,LRRCC1,IL6ST,JAK2,KLHL23,STXBP5,SFXN5,MARK1,CHIC1,SAMD5,MYO7A,NCAM2,NELL2,NTRK3,NUCB2,LOC100128398,P2RY1,PCDHGC3,GNG2,PFKFB3,SEMA5B,PIK3C2A,KCTD15,NLE1,PRIMPOL,LRP12,PPP2R5E,MAPK4,HYDIN,ELOVL2,CCDC40,FAM66C,RET,UBR7,LGI2,GSTCD,NEK11,EPHA10,SPIN3,GLDN,AP1AR,CASC3,RASA3,KIF21A,SH3GL3,FNDC3A,ST6GAL1,CNKSR2,PPP4R3A,ANKRD36,HECW1,ERC1,UNC5B,PEG10,RBM26,ATP10B,SSTR1,ELOVL4,SEPT8,DIP2A,STXBP1,VPS13A,SYN2,TCEA1,DMXL2,CUX2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,NAT16,DOCK9,PHF24,USP32P1,GPRIN3,SIRT1,DICER1-AS1,TK2,SMUG1,TRO,STXBP4,TTC3,ZKSCAN5,WIPF1,LAT2,XPO1,ZBTB14,ZNF24,MKRN3,ZBTB38,POLR3H,ANKS1B,FIP1L1,PHTF2" MicroRNA hsa-miR-153:mirSVR_highEffct hsa-miR-153:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.93E-68 2.76E-64 2.87E-67 2.64E-66 166 896 "VWA5B2,RALGAPA1,KCNH8,NCKAP5,CCDC85A,GALNT13,KIAA1211,RNF150,SLC24A4,HECW2,HACE1,OSBPL6,CC2D2A,SPARCL1,ALCAM,ABCD2,EP400,PKP4,APC,TNRC6C,USP37,SEMA4G,CDK13,NUMB,SLC4A4,ATP1B3,ATP2B2,N4BP2L1,BACH1,DST,LRBA,LRRFIP1,MAGI1,CFL2,CHN2,QKI,MAP4K4,CNN3,AKAP6,RCHY1,RTTN,CREM,FAM169A,DZIP3,PHF14,CCDC144A,BOC,RIPOR2,ARHGAP24,KIAA0586,KLHL3,GRIN3A,DMD,DTNA,MAMLD1,AASDH,FCF1,GOLGA7,STARD3NL,CALCRL,MFSD10,IGSF6,DNAJC27,RASL12,SH3YL1,SCML2,SEC24B,NBEA,UFM1,CAMKK2,AP4B1,ERAP1,SIGLEC8,GATM,TNRC6A,MSL3,GPD2,PCLO,MAP4K5,RASSF8,ZDHHC15,SCIN,KCND1,KCNJ16,IPO5,MARK1,MAT2A,MATN2,MBNL1,LRP1B,MEST,KCTD6,MOV10,TAGLN3,LAYN,NEK1,NFE2L2,NNAT,NOVA1,CCSER2,PLIN1,LRP12,EPB41L4B,PPP3CA,KANSL1,EPDR1,HYDIN,PTCH1,BDNF-AS,ZSCAN32,PTPRD,ZSCAN2,USP47,FAM66C,FAM184A,RIC8B,ROBO2,RORB,EPHA10,ABCA11P,RYR3,SATB1,MRAS,FAM102A,FNDC3A,FAM81A,WDR47,ARHGEF40,SLC14A1,BTBD7,GKAP1,SNAP25,MBD5,CMTR2,SNRPN,ZC3H13,RBM26,TROVE2,MPRIP,PLCB1,COBL,DMXL2,SATB2,OBSL1,RNF216P1,ZFPM2,SLC44A1,SYNPO2,TRPS1,SSBP2,SGK3,FLRT2,BCL2L13,CCDC136,WIPF1,PCDH20,ZNF28,SPHK2,ZNF138,LAMP5,CADM2,TMEM178A,PDSS2,RGS7BP,FZD3,JMJD1C" MicroRNA hsa-miR-93:PITA hsa-miR-93:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-106b:PITA hsa-miR-106b:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-106a:PITA hsa-miR-106a:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-20b:PITA hsa-miR-20b:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-20a:PITA hsa-miR-20a:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-17:PITA hsa-miR-17:PITA_TOP PITA 5.31E-68 2.97E-64 3.07E-67 2.83E-66 157 800 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,XRN1,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-449b*:mirSVR_highEffct hsa-miR-449b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.07E-68 3.96E-64 4.08E-67 3.76E-66 161 844 "KCNH8,ACTN1,KDM5D,AP2A2,WDR35,HFM1,FAM135A,AMPD3,OGT,MAP4K3,SMIM29,APC,UPRT,VAT1L,TMEFF1,CADPS,TMEM108,KIF1A,TTLL9,CACNA1B,LURAP1,CALB1,PTBP2,CAMK2A,PRC1,CLDN10,MTMR7,LRBA,DLGAP1,RCBTB2,SRSF11,RAB28,PPT2,SRP14-AS1,ARMC8,LETMD1,SLC4A8,ZFP28,CRMP1,SEC24C,RIMS2,DCAF4,CYBB,HDAC9,ARHGAP24,EARS2,C2CD2L,DDX46,ECM2,GOLT1B,E2F5,ANKRD46,PHF20L1,KMT5B,COPS4,STARD3NL,EIF1,ENO2,VPS13B,LRRC17,ST3GAL6,FGF13,MEX3B,DCTN2,TRMO,ST6GALNAC3,GALC,WASHC2A,TCERG1,TOX3,MAP7D2,STON1,CNTRL,SERP2,GRM2,RABL2A,PSIP1,IRAK3,IGFBPL1,SHISA6,MSL1,RBPJ,KIT,LAMP2,PAXBP1,MBD1,TM6SF1,MEF2C,SCAMP5,BLOC1S2,P2RY13,NCAM2,NDP,GPR137C,PDE4B,PDPK1,OLA1,SERPINI1,PRIMPOL,LRP12,SEPT4,MINDY2,PPM1B,PPP3CC,PRKACB,PKIA,MAPK9,HYDIN,RELN,PIGG,SPDL1,TMEM260,STK32A,C1orf109,TMEM255A,RBBP6,HKR1,ZDHHC4,PBRM1,RORB,SPIN3,KCNIP1,CLIP1,SEMA6D,SCN8A,SUPT20H,ZFP30,KIF21A,SH3GL3,FERMT1,KIF16B,HKDC1,NUBPL,KANSL3,CDK5RAP2,SNCA,SNRPN,MYO16,KDM4B,KDM3A,SPP1,ZC3H13,POGZ,DIP2A,NUDT10,ADGRL3,KLHL4,SIN3B,SATB2,ZEB1,SIRT1,ASXL3,BHLHB9,TRIO,PLEKHH2,CCDC136,ZNF711,ZNF17,LYPD6,ZXDA,RNF170" MicroRNA hsa-miR-34a*:mirSVR_highEffct hsa-miR-34a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.11E-68 3.98E-64 4.10E-67 3.78E-66 182 1079 "RALGAPA1,KCNH8,PCDH19,RTL9,OSBPL6,TAOK1,ADGRF5,C1QTNF3,ANK2,PKP4,PARG,APAF1,UPRT,PLA2G4C,SCAPER,JAZF1,THSD7A,CALM1,KRIT1,LRBA,CFL2,CHN2,NDST3,CLTC,SULT4A1,CNN3,CNTFR,FAM149A,AKAP6,SLC4A8,RTTN,SLC35F1,CPS1,AKAP12,HAPLN1,ABCG1,CSNK1G3,PDE4DIP,CYBB,HDAC9,ZFYVE16,JAKMIP2,DDX46,RHOBTB1,PLPPR4,SV2B,ZNF582-AS1,SLC25A18,PDCD6IP,ECM2,DNAJB6,GOLT1B,AASDH,ANKRD46,FCF1,KLHL5,FSD1L,PHF20L1,EGFR,EIF4G2,PLEKHA1,GPHN,GMPR2,ACSL4,FCGRT,FDFT1,GORAB,SEC24B,FER,FGF14,FGFR1,POLK,RGPD5,TMEM107,SPECC1,STAMBP,AP4B1,SDCBP2,GABRG2,GAD1,C15orf41,PCDH17,PPARGC1A,BRD8,COPS8,SPIN1,RAB30,LNX1,PCLO,PRDM5,HAS2,ZHX1,FRMD5,TNFAIP8L3,HMGCR,HNMT,RBPJ,ZNF678,KCNH2,KIF5A,LAMP2,PAXBP1,NCOA7,MAT2A,MITF,MSR1,MT1M,MXI1,RTL5,CNOT4,DNHD1,CHAMP1,LOC100128398,GPR137C,CNTN3,OLA1,ABCB1,RANBP3L,MAPK9,RELN,SAMD9,SNRK,SPDL1,ACSM5,RAD51D,ZNF493,LGI2,MRAP2,MCMBP,RPS20,RTN1,RMI1,SCN7A,SCN8A,NLGN1,FAM81A,SLC12A2,ATF7IP,TET1,RCOR3,MBD5,SNRPN,USP33,SP4,CDK19,LMO3,CLASP2,ITPRID2,SSTR2,NKAIN2,TTBK2,ADHFE1,VPS13A,SYT1,COBL,CAMTA1,ADGRL3,DMXL2,ZEB1,RPGRIP1L,SYNE1,CSMD1,SYNPO2,RUNDC3B,TTTY15,TTC3,UGT8,P2RY12,LAT2,WRN,NPDC1,RICTOR,XPO1,ZFP37,ZNF711,ZBTB38,ZSCAN26,PRDM10,RNF103,URM1,ADAMTSL3,NETO1" MicroRNA hsa-miR-519d:PITA hsa-miR-519d:PITA_TOP PITA 7.66E-68 4.29E-64 4.41E-67 4.06E-66 157 802 "USP31,SLC24A4,APBB2,USP37,SEMA4G,STK33,MARK4,RASL11B,SLC4A4,ATP2B2,DPY19L3,NRP2,ARHGEF7,MTMR3,JAZF1,USP6,DLGAP2,CFL2,SOCS6,B4GALT6,QKI,PCYT1B,AKAP5,AHCTF1,ZNF385A,CLOCK,CRY2,LRIG1,ARHGEF10,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,EPB41,ETV1,DNAJC27,EZH1,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,RUNDC3A,RAB30,TNRC6A,CIT,HAS2,HLF,KIF5A,CAMK2N2,SFXN5,SYTL4,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,GPR137C,CNTN3,PFKFB3,PIK3R1,CCSER2,RETREG2,EPB41L4B,PPARA,PPP1R1A,PPP3CA,PKIA,MAPK9,PSD,PTPRD,PTPRO,CEP97,OXR1,GTDC1,SLC25A36,ST6GALNAC6,SALL1,CSRNP3,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLC11A1,TET1,TMCC1,FAM126B,ARHGAP26,LMO3,ITPRID2,ERBIN,RGL1,SYNE2,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,RIMBP2,TNS1,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,MAP3K12,EMSY,CADM2,SLC17A7,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-495:PITA hsa-miR-495:PITA_TOP PITA 7.96E-68 4.45E-64 4.58E-67 4.22E-66 151 740 "KDM5D,MTA3,TAOK1,ALCAM,ARHGAP20,TRMT9B,AMPH,DPP10,TMEFF1,ZBTB10,NCOA1,EIF4G3,ATP2A2,ATP2B2,ADGRB3,ST3GAL5,FUBP1,JAZF1,LDLRAD4,CACNA2D1,CAMK2A,CAMK2G,CAST,RUNX1T1,CLDN10,CERS5,CBFA2T2,SEPT7,LARGE1,MAGI1,SRSF11,CHN2,LHX2,NRXN3,CNR1,ARMC8,SLC35F1,CLOCK,CSNK1E,RIMS4,PLCXD3,USP6NL,DOCK4,LONRF1,KCTD8,PABPC5,BRINP1,DBT,MYEF2,MFAP3L,RHOBTB1,SPOCK3,E2F5,KLHL5,MBNL2,TENM1,RGS17,EPB41L2,ETV1,KATNAL1,ACSL4,DLC1,GORAB,PRKAG2,SUCO,FOXO3,AFF2,CELF1,PCDH17,TNRC6A,FERMT2,ADGRA3,GPD1,FAM19A2,ADAMTS6,BACH2,HLF,HNF4G,NEGR1,HSF2,IGF1,SMAD1,MARK1,NEXMIF,PCDH9,PDE4D,PLCL1,LRP12,EPB41L4B,MINDY2,PPP2R2C,PPP3CA,MAPK10,PTCH1,PTK2,PTPN13,PTPRD,PTPRE,NKAIN1,KHDRBS2,RET,PRRT2,GTDC1,PBRM1,ZFHX4,RORB,SNX22,FBXW7,MCMBP,SALL1,SATB1,SCN8A,SGK1,CPEB3,CHD9,FBXO11,R3HDM2,SLC8A1,TRIM67,SNAP25,FAM126B,FAM219A,SP4,CLASP2,POGZ,SSTR1,MPRIP,NSFL1C,RHBDL3,ANKRD12,CAMTA1,FAM208A,TCF4,RPGRIP1L,SIRT1,HEY1,R3HDM1,RASD2,TSN,RPRM,FAM155A,UBE3A,ZBTB14,ZFAND5,EMSY,FIP1L1,RTN4,KAT6A,ACTR3B,ST8SIA2,CPNE4" MicroRNA hsa-miR-509-5p:mirSVR_highEffct hsa-miR-509-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-67 6.02E-64 6.19E-67 5.70E-66 171 956 "RALGAPA1,BRAP,OSBPL1A,TAOK1,ADGRF5,AMPD2,MAP4K3,VAT1L,CDC14B,ASGR1,NUMB,DPY19L3,ADGRB3,ARHGEF7,THSD7A,CAST,RUNX1T1,ZNF501,KRIT1,METTL6,CD38,LRBA,ARHGEF2,LRRFIP1,NPIPA1,SRSF11,PPT2,CNTN1,AKAP6,COL4A5,ZNF521,ENTPD4,TRIM69,OSBPL3,SIPA1L1,PHACTR3,KCTD8,DDX46,SACS,WDR20,CHRDL1,USP3,DPYSL2,GOLT1B,EDIL3,EDN3,YAF2,EGR3,KCTD3,VPS13B,COQ7,RABEPK,ABCA8,CORO2B,MED12L,GTF2IRD2,OLFM1,SPSB4,BAIAP2,TMEM164,PRKAG2,FHL1,SYNCRIP,RGPD5,JKAMP,NBEA,TMEM107,SMC2,FYB1,GALC,IP6K3,ERAP1,NEU3,TUBGCP4,MSTN,ARFIP1,SESN1,GHR,TOX3,TNRC6A,MSL3,ZNF638,WDFY3-AS2,ADGRA3,TDRKH,FUT10,GRIA2,CLASRP,UBE2QL1,ZHX1,IL6ST,ZNF678,KCND2,SYTL4,HECTD2,MBNL1,MEIS1,MN1,NF1,NRCAM,SETD4,OGG1,PCDH8,ENPP2,GPR85,CCSER2,RETREG1,MAPKAP1,EPB41L4B,LRRN3,KANSL1,RELN,BCAS3,CYBC1,SPDL1,TMEM260,ZSCAN32,PTPRB,PTPRD,PTPRE,NKAIN1,RADX,MORC4,GTDC1,FIGN,ZFHX4,CCDC82,CARF,RPL15,RYR3,NCBP3,SCN7A,PEAR1,CASC3,SCAF8,KIF21A,FBXO11,FNDC3A,NLGN1,ATF7IP,TET1,RCOR3,USP33,FNBP1,KDM3A,KDM4C,ZNF423,CLASP2,CLSTN2,SSPO,NECAB1,SYN2,SLC37A2,FBXW11,ZEB1,TRIM2,RPGRIP1L,PCDHB7,ITGB3BP,AKTIP,BHLHB9,ERCC6L2,VLDLR,RICTOR,ZNF24,POLR3H,UPF3A,MFF,STOX2,MPPE1,UBE3B" MicroRNA hsa-miR-140-5p:mirSVR_highEffct hsa-miR-140-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.29E-67 7.24E-64 7.44E-67 6.85E-66 163 869 "GALNT16,ZNF608,INTS2,OSBPL6,SPARCL1,CEP126,LTBP4,OGT,DPP10,ANK2,MAGEE2,LGR5,PPP4R4,CADPS,NCOA1,TTLL9,BACH1,SEC11C,WASF1,CA4,CALB1,THSD7A,CAST,DGKI,LRBA,ZMYM4,UBE2L6,CNOT8,CNTN1,SLC4A8,BAG4,RBM39,GDA,SNCAIP,CSNK1E,OSBPL3,CSNK1G3,PDE4DIP,ERC2,PNPLA8,CYBB,DGKB,DAPK1,DDX46,DYNC1I1,DMTF1,DPYSL2,MAMLD1,KLHL5,SUGP2,AASS,EIF4G2,CERCAM,EPB41L2,RABEPK,CHST15,POLK,VTI1B,ANKFY1,JKAMP,CELF1,STAU2,FYB1,GALC,RAPGEF6,C15orf41,INPP5K,LRRC37A6P,SRCAP,TCERG1,MSL3,KDM2B,FAM19A2,HMGCL,HNF4G,ZDHHC15,SMAP1,FAM69A,KCNN2,TTYH2,LAMP2,HECTD2,MAN2A2,MAP4,MARK1,MBD1,GIT1,MYO6,MYO9A,NFE2L2,NUCB2,TBC1D25,ZNF827,STRN3,ING3,EPB41L4B,DRAM2,CEP41,PKIA,MAPK9,PRODH,SNRK,BDNF-AS,TMEM260,PTPRO,RBBP6,TRIM68,RFX3,RIC8B,NUDT11,CARF,NEK11,MEG3,ATAT1,RTN1,RYR3,AP1AR,SCN8A,FNIP1,SUPT20H,HSPA4L,SGK1,SH3GL3,ASAP3,SHC4,NLGN1,SMARCC2,SNRPN,MYCBP2,ATP10B,STX1A,ANKRD28,ANKRD12,TAL1,ADGRL3,SATB2,ZEB1,TRIM2,PCDHB9,PCDHB4,DNAH7,GPR161,HEY1,TLR4,R3HDM1,NPL,RGMB,AMACR,RUSC1,TSC1,ZKSCAN5,SLC35A4,UGT8,VLDLR,LAT2,SLC47A2,ZNF540,ANKS1B,LAMP5,NAV3,WNK2,RNF170,FXR1" MicroRNA hsa-miR-1276:mirSVR_highEffct hsa-miR-1276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-67 7.44E-64 7.63E-67 7.03E-66 188 1154 "NCKAP5,ADCY6,INTS2,KLHL13,KCTD16,HFM1,SEMA6A,ALCAM,ABCD2,ARHGAP20,AMPH,DPP10,MAP4K3,PARG,APC,APLP1,N4BP2L1,CFLAR,BMP7,SYNJ2,ARHGEF7,FUBP1,MTMR3,LURAP1,KALRN,SPAG9,RUNX1T1,CBR1,CERS5,MAGI1,NUMBL,TPP1,QKI,TMEM184B,SRP14-AS1,AKAP7,AHCTF1,CNRIP1,RBM39,HINFP,CSF1,CSNK1G3,VCAN,PDE4DIP,PHACTR3,APPL1,ARHGAP32,ZFYVE16,PABPC5,MYEF2,KIAA0319,POM121,RHOBTB1,SV2B,KIF19,CHRDL1,DLX1,MED12,DTNA,DTNB,ABCC5,EDNRA,ANKRD46,SEMA3D,FAM13A,KMT5B,STARD3NL,F8,ABCA8,GORAB,MED12L,PRKAG2,FHL1,RGPD5,SLC37A3,SMC2,CELF1,SDCBP2,ZNF44,TRAF3IP2,ERAP1,KIAA1841,ARFIP1,PPARGC1A,SPIN1,TOX3,TNRC6A,DCLK2,PRRC2B,PRUNE2,PCLO,GRB10,FAM19A2,AP4S1,IRF8,MSL1,KCNN2,ZNF667-AS1,MARK1,MAT2A,LRP1B,MITF,AFDN,ZNF92,NEK1,NF1,NOVA2,DNHD1,SLC11A2,NTRK3,OCRL,CLDN11,OLA1,PLIN1,SLC25A23,ING3,EPB41L4B,PRKACB,GRAMD1C,WDR25,PIGG,PTPRD,OXR1,ZMAT4,LGI2,CARF,GSTCD,RORB,ADAL,LRRK2,ATAT1,CLIP1,ZNF354C,TRAPPC13,SCP2,RASA3,KIF21A,SYBU,SEC31A,KANSL3,KBTBD4,TET1,CPEB4,TTC17,KDM4B,CDK19,LMO3,ZC4H2,MPRIP,NECAB1,SYNE2,NUDT10,SYT1,FAM208A,FBXW11,SYNE1,PUM2,SIK3,SIRT1,ITGB3BP,RGMB,TRIO,PPIL6,TSN,HSPBP1,SGK3,UCHL1,CCDC14,WIPF1,ZFP37,ZNF28,CELF4,DHX33,EMSY,CADM2,RNF103,ADAMTS9,NAV3,WNK3,RGS7BP,KAT6A,PHTF2,ADAMTSL3,TIGD6,FRMD6,NETO2,GAN,SENP7" MicroRNA hsa-miR-4275:mirSVR_highEffct hsa-miR-4275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-67 8.32E-64 8.53E-67 7.85E-66 171 958 "CLK4,KLHL32,ADD2,BRAP,PWWP2A,KLHL13,OSBPL8,CC2D2A,SPARCL1,SMIM17,PCDH10,OGT,LRCH2,LCORL,PHF12,EPB41L5,UPRT,CASK,LINC00173,BMPR1B,NAE1,CACNA1G,THSD7A,SLC25A14,CBR1,ZNF501,C1orf52,LRBA,LRRFIP1,COL11A2,ZFP28,PREPL,ARHGEF10,CSNK1E,PHF14,CCDC144A,ZFYVE16,MATR3,BRINP1,ARMCX4,MYEF2,SPOCK3,WDR20,NR1D2,GOLT1B,E2F6,AASDH,FAM13A,PHF20L1,APH1A,MBNL2,KCTD3,EIF4G2,TMEM35A,EIF1,VPS13B,COQ7,STX2,RAB9B,DENND4A,TLR7,KATNAL1,TMEM132C,DLC1,CEP78,FGF1,NELFCD,SMC2,CELF1,CHL1,GABRG2,IQGAP2,MTHFD2,GATM,PPARGC1A,LYVE1,HPGDS,DBF4,ZNF638,ADGRA3,GPD2,SOX21,PSIP1,SMAP1,RBPJ,TJAP1,INSM1,SLC35G1,KTN1,MAP2,MBD1,AFDN,MSR1,NF1,OCRL,GPR137C,PRTG,PDE1C,PDE4D,SLC10A4,NALCN,CCSER2,FAM216A,PLIN1,PRIMPOL,PDZRN4,SCHIP1,SEPT4,EPB41L4B,POLR2F,MINDY2,TATDN3,MASP1,NDUFS7,VPS13C,ANKHD1,STK32A,ZNF615,ENOX1,RET,RFX3,NUDT11,ZNF532,DCUN1D2,ROBO2,PEAR1,SUPT20H,ARX,SYBU,NAPB,RCOR3,CMTR2,DOK5,MYCBP2,ERC1,ZNF423,ZC3H13,POGZ,LARP4,NKAIN2,SEPT3,ZC3H4,VPS13A,PJA1,CAMTA1,TAF6,TBCEL,CLASP1,SZT2,DOCK9,PUM2,FRYL,SIK3,FAM200B,SLC44A1,HEY1,BHLHB9,TMPO,CSMD1,NPL,RGMB,RUNDC3B,TSC1,ZIC2,MICU3,FTSJ1,EMSY,PDSS2,JMJD1C,TRAM2-AS1,IFT88" MicroRNA hsa-miR-504:mirSVR_lowEffct hsa-miR-504:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-67 1.01E-63 1.04E-66 9.54E-66 211 1441 "EMILIN3,GALNT16,ADCY6,ADD2,ADRA1D,RTL9,TXNDC16,C1QTNF3,SEMA6A,CARNS1,SYT13,DOC2A,ZFAT,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APOC2,BCAS1,SFMBT2,SPTBN4,CDK13,TMEM108,DPY19L3,DOCK11,ADAM23,ADAM15,LINC00847,SGCE,CFAP410,CALM1,CBS,USP2,CD86,LRRFIP1,ABCG2,CNGA3,IGLON5,PICK1,CNTFR,AKAP7,RCHY1,SMARCAL1,SEC31B,NCOR2,ABCG1,SNCAIP,VAC14-AS1,ERC2,TBC1D5,DAPK1,ZC3H11A,WDR20,RAB39B,DNAH9,SLC29A4,DPH1,DNAJB6,ABCC5,KRBA2,EBF1,PHC2,RASGRP1,YAF2,PHF20L1,SUGP2,RASA4,PLEKHA1,C3orf18,EMX2,VPS13B,EPB41,EPHB1,ETV1,VPS26C,DNAJC27,TLR7,RPS6KC1,FCGRT,PPP1R1B,FGFR1,PRKAG2,HPCAL4,FLT1,NOP56,EFCAB2,AP4B1,GABRB3,GHDC,MTHFD2,SEPT9,INPP5K,IGSF5,GCNT2,GGT7,SPIN1,HTATSF1,KCNMB4,GPT2,PRRC2B,LILRB4,TMEM121B,GRIK4,ZNF496,BTN2A1,CLASRP,MUM1,BACH2,VSIG4,ELOVL5,ZNF491,C9orf129,ICA1,IRF8,KIF5A,HECTD2,ASPRV1,CLEC18A,MAN2A2,ZFYVE27,MAP4,MBP,PPM1L,MXI1,NFIX,NNAT,SLC11A2,NUCB2,PDPK1,ZNF655,CCSER2,SMIM7,LRP12,SCHIP1,VSTM2L,HYDIN,PRPH,CNNM2,MTMR10,ZSCAN32,PTPRE,TTC13,ZDHHC14,RFX2,RGS12,KLHL11,CCDC82,EXD2,PNMA8A,KIRREL1,SNX22,RPL15,ADAL,EMID1,ST6GALNAC6,ATAT1,DGLUCY,ATXN2,SCN2B,TNFRSF19,SMPD3,MRAS,TRA2B,FERMT1,HKDC1,ANKRD6,SLC14A1,NAPB,SMARCA4,ANKRD36,SNCA,MBD5,FAM126B,FNBP1,SPP1,SPART,POGZ,SSTR2,ZC4H2,ST5,SEPT8,ARHGEF9,SYN2,C12orf76,MTCL1,PDLIM2,SMG6,DMXL2,SIK3,RNF216P1,VWCE,AP4E1,AKTIP,LRRC8A,CSMD1,TRIO,STXBP4,UGT8,FLRT2,PLEKHH2,VLDLR,CLIP2,CLDND1,GUSBP1,CRB2,LYPD6,ZFAND5,TMEM178A,PLSCR4,SPATA13,SENP7,JPH3" MicroRNA hsa-miR-29a:mirSVR_highEffct hsa-miR-29a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.85E-67 1.04E-63 1.06E-66 9.76E-66 176 1016 "KCNH8,NCKAP5,KDM5D,XKR4,PTCHD1,OSBPL6,TXNDC16,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APC,TMEFF1,CDK13,STX16,ATP2A2,N4BP2L1,ADGRB2,PROM1,DST,WASF1,PTBP2,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,GDA,TRIM69,CRYM,CS,LRIG1,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,RHOBTB1,EXOG,GRIN3A,DYNC1I1,DNM1L,EDNRB,FEM1B,PHF20L1,KMT5B,ELN,TUBD1,SCML2,MED12L,GTF2IRD2,MEX3B,RGPD5,DCTN2,TPK1,ST6GALNAC3,OGA,GABRG2,DISC1,SESN1,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,GPR37,PCLO,ADAMTS6,ZHX1,VSIG4,HMGCR,HNF4G,IGF1,ZNF678,KIF5A,LAMA2,LIMS1,HECTD2,MAP6,MARK1,MEST,MYCN,NEXMIF,ENPP2,GNG2,CCSER2,PURG,PMP22,SDK2,ING3,EPB41L4B,PRKAB2,RASGEF1B,MAPK9,SLC26A11,VPS13C,SNRK,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,CCDC82,ROBO1,PCMTD2,FBXW7,SALL1,TRA2B,SGK1,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,NAPB,ELMO2,BTBD7,TET1,ZKSCAN3,MYO16,HECW1,KDM4C,SPTAN1,NXT2,ZSCAN29,ELOVL4,PRRC2C,SYP,TBCEL,TCF4,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,R3HDM1,TPM1,TSN,TUBB2A,CLHC1,UGT8,ZNF19,ZNF28,ZNF45,NDRG4,EML6,DPYSL5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,CASC15,IFT88" MicroRNA hsa-miR-1270:mirSVR_highEffct hsa-miR-1270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-67 1.19E-63 1.21E-66 1.12E-65 180 1063 "KCNH8,HECW2,CC2D2A,TAOK1,ARHGAP20,BBOX1,FAM135A,OGT,APAF1,ARNTL,STK33,CCDC74A,ATP1B3,N4BP2L1,ATP6V1G2,TTLL9,ADGRB3,IL33,CACNA1B,THSD7A,KALRN,PTBP2,CCNH,LRBA,ARHGEF2,MAGI1,TIGD7,RCBTB2,LHX2,FAM19A5,PCYT1B,COL4A5,SUMF2,SLC35F1,VCAN,HDAC9,EARS2,IST1,PITPNC1,YTHDC1,MFAP3L,ALKBH8,RHOBTB1,ZNF582-AS1,DMD,NR1D2,CPEB2,DTNA,AASDH,EDIL3,CNNM1,YAF2,PHF20L1,APH1A,MBNL2,COPS4,RGS17,TMEM35A,C8orf37,EPHB1,PIPOX,F8,CLVS1,FAM198B,TMEM132C,FCGR1A,CEP78,ZNF589,SLC9B2,MED12L,FGF13,FGFR1,PRKAG2,SPECC1,APOPT1,KHDRBS3,FYB1,ZMAT1,GABBR1,GGT5,PPARGC1A,GLI2,GLYR1,ZNF638,DCLK2,GPR12,MCHR1,ZNF496,RASSF8,ACOT7,HMGCL,SHISA6,IRF8,ZIC5,LRRCC1,FAM69A,NME9,JAK2,KCNJ5,KIF5A,HECTD2,AFDN,MSR1,MYO7A,MYT1,NEK1,NFE2L2,NRCAM,NTRK2,P2RY1,GLIPR1L2,CNTN3,PRTG,OLA1,PCDH18,NECAB2,MAGEL2,EPB41L4B,HYDIN,RELN,VPS13C,WDR25,BDNF-AS,TMEM260,CASTOR1,USP47,RADX,HKR1,GTDC1,SLC25A36,TMLHE,MEG3,CSRNP3,SCP2,COPZ1,ZFP30,SHC4,NUBPL,DHX30,SLC12A4,BTBD7,SLC22A4,LIMCH1,SNRPN,MYO16,PDZD2,FNBP1,HECW1,KDM4C,RBM26,LMO3,CLASP2,CLSTN2,SST,NXT2,STAU1,ELOVL4,ZC3H4,PLCB1,MTCL1,FAM208A,TRIM2,SYNE1,FAM189A1,SIK3,DICER1,C18orf54,AP4E1,BEX4,TPM1,UGT8,OSBP2,USP1,LYPD6,DHX33,EMSY,NAV3,EPM2A,ST7,RNF170" MicroRNA hsa-miR-27a:PITA hsa-miR-27a:PITA_TOP PITA 2.28E-67 1.27E-63 1.30E-66 1.20E-65 143 665 "RALGAPA1,ELFN2,ADCY6,PLEKHH1,USP31,ZNF608,TAOK1,SEMA6A,ALCAM,PITPNM2,APAF1,APBA2,PDE8B,NCOA1,STX16,RNF182,DPY19L3,CACNA1A,C1orf52,ZMYM4,MAGI1,FOXN3,SOCS6,CLCN3,QKI,CNN3,CNR1,ARMC8,CABP1,ZNF385A,SLC35F1,HAPLN1,RGS6,ERC2,LONRF1,SPATA2,POM121,NR1D2,ARRDC4,EDNRA,MBNL2,EGR3,EIF5,RGS17,TMEM35A,EPB41,RCAN2,EYA1,FGF12,FGF13,SUCO,ST6GALNAC3,DOT1L,BRSK1,GABRB3,CSDC2,RUNDC3A,GPD2,TMEM121B,GRIN2D,CIT,PTPRT,FAM222A,ZHX1,MIER3,HNF4G,AGFG1,SOWAHA,ZIC5,LIFR,NCOA7,SMAD1,MARK1,AQP11,MATN3,CHIC1,MEIS2,KITLG,MN1,MSI1,MXI1,MYT1,ZC3H12B,NF1,NFE2L2,NOVA1,OPA1,ZNF827,CDK18,PDE3A,PDPK1,PPARA,CEP41,PKIA,RELN,WBP1L,FAM184A,ENOX1,RET,ZFHX4,SETD5,ALG9,FBXW7,HUNK,RXRA,NCBP3,SEMA6D,SMPD3,CASC3,FAM102A,PPM1E,CPEB3,CCDC92,SLC8A1,TET1,CPEB4,RCOR3,SNAP25,TMCC1,FAM126B,SOX11,KDM3A,TEX2,SSTR1,LARP4,SS18,SEPT8,STX1A,SYT1,CAMTA1,PDLIM2,SATB2,TRIM2,RPGRIP1L,FRYL,CSMD1,TSC1,GORASP1,FLRT2,MICU3,TMEM237,JMJD1C,ADAMTS10" MicroRNA hsa-miR-27b:PITA hsa-miR-27b:PITA_TOP PITA 2.28E-67 1.27E-63 1.30E-66 1.20E-65 143 665 "RALGAPA1,ELFN2,ADCY6,PLEKHH1,USP31,ZNF608,TAOK1,SEMA6A,ALCAM,PITPNM2,APAF1,APBA2,PDE8B,NCOA1,STX16,RNF182,DPY19L3,CACNA1A,C1orf52,ZMYM4,MAGI1,FOXN3,SOCS6,CLCN3,QKI,CNN3,CNR1,ARMC8,CABP1,ZNF385A,SLC35F1,HAPLN1,RGS6,ERC2,LONRF1,SPATA2,POM121,NR1D2,ARRDC4,EDNRA,MBNL2,EGR3,EIF5,RGS17,TMEM35A,EPB41,RCAN2,EYA1,FGF12,FGF13,SUCO,ST6GALNAC3,DOT1L,BRSK1,GABRB3,CSDC2,RUNDC3A,GPD2,TMEM121B,GRIN2D,CIT,PTPRT,FAM222A,ZHX1,MIER3,HNF4G,AGFG1,SOWAHA,ZIC5,LIFR,NCOA7,SMAD1,MARK1,AQP11,MATN3,CHIC1,MEIS2,KITLG,MN1,MSI1,MXI1,MYT1,ZC3H12B,NF1,NFE2L2,NOVA1,OPA1,ZNF827,CDK18,PDE3A,PDPK1,PPARA,CEP41,PKIA,RELN,WBP1L,FAM184A,ENOX1,RET,ZFHX4,SETD5,ALG9,FBXW7,HUNK,RXRA,NCBP3,SEMA6D,SMPD3,CASC3,FAM102A,PPM1E,CPEB3,CCDC92,SLC8A1,TET1,CPEB4,RCOR3,SNAP25,TMCC1,FAM126B,SOX11,KDM3A,TEX2,SSTR1,LARP4,SS18,SEPT8,STX1A,SYT1,CAMTA1,PDLIM2,SATB2,TRIM2,RPGRIP1L,FRYL,CSMD1,TSC1,GORASP1,FLRT2,MICU3,TMEM237,JMJD1C,ADAMTS10" MicroRNA hsa-miR-146b-5p:mirSVR_highEffct hsa-miR-146b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.32E-67 1.30E-63 1.32E-66 1.22E-65 179 1052 "KCNH8,CLK4,KIAA1211,ESYT2,ADRB2,DPY19L2P4,INTS2,RTL9,KIAA1324,SPOP,FAM135A,AMPH,CASK,ARRB1,NCOA1,NUMB,NRP2,BMPR1B,SYNJ2,JAZF1,GYG2,RAB29,LURAP1,KALRN,RUNX1T1,CLDN10,CCK,USP6,USP2,DIS3L,CFL2,EPS15L1,ABCG2,ARMC8,COL4A5,ANKRD35,COL9A1,SLC4A8,ABI3BP,GDA,SEC24C,APPL1,PHF14,PUM1,CCDC144A,DOCK4,ZBTB24,C2CD2L,RAB39B,DMD,USP3,CDON,ACOT8,DTNA,ABCC5,EDNRB,FCF1,RASGRP1,FRY,YAF2,PHF20L1,GOLGA7,KCTD3,EIF4G2,PCOLCE2,TUBD1,MRPL37,SIRPB1,CLVS1,SH3YL1,SCML2,GORAB,SLC9B2,AMOTL2,FHL1,MEX3B,RGPD5,STAMBP,CELF1,CSPG5,MSANTD4,SARAF,FYB1,MTHFD2,MSTN,MALT1,RUNDC3A,COPS8,SPIN1,KDM2B,TDRKH,PCLO,STMN2,CIT,HAS2,HMGCL,IL6ST,ITPKB,KCNJ16,STXBP5,HECTD2,MARK1,SRSF12,MID1,MMP16,ZNF92,ZC3H12B,NOVA1,CLDN11,NLGN3,PURG,SCHIP1,MAPK10,DIRAS2,DCHS2,BCAS3,TMEM260,STK32A,PTPRE,PID1,USP47,ZNF493,RBBP6,ERI2,RIC8B,ZFHX4,ZNF532,CARF,PNMA8A,ROBO1,SNX22,MCMBP,ADAL,ZNF331,DGLUCY,SH3BGR,FERMT1,WDR47,CCDC88A,DMRTC1,TTC17,USP33,PDZD2,PEG10,DBNDD2,PBLD,CLASP2,ZC4H2,ZSCAN29,SYNE2,SYT1,ANKRD28,ANKRD12,ADGRL3,KLHL4,RPGRIP1L,DOCK9,SLC19A3,ARL10,ERCC6L2,TPM1,RGMB,RUNDC3B,PPIL6,ZKSCAN5,TUBB1,SLC35A4,PLEKHH2,ZIC1,ZNF32,TRIM9,ZNF540,ZNF138,ZNF142,CADM2,PLSCR4,SMIM8,PHTF2,FXR1" MicroRNA hsa-miR-509-3-5p:mirSVR_highEffct hsa-miR-509-3-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-67 1.44E-63 1.46E-66 1.35E-65 169 939 "RALGAPA1,BRAP,OSBPL1A,TAOK1,AMPD2,MAP4K3,VAT1L,CDC14B,ASGR1,NUMB,DPY19L3,ADGRB3,ARHGEF7,THSD7A,PTBP2,RUNX1T1,ZNF501,KRIT1,METTL6,CD38,LRBA,ARHGEF2,LRRFIP1,NPIPA1,SRSF11,CNTN1,FAM149A,AKAP6,COL4A5,ZNF521,ENTPD4,TRIM69,SIPA1L1,PHACTR3,KCTD8,DDX46,SACS,WDR20,CHRDL1,USP3,DPYSL2,DTNB,GOLT1B,EDIL3,EDN3,YAF2,EGR3,KCTD3,VPS13B,COQ7,ABCA8,CORO2B,MED12L,GTF2IRD2,OLFM1,SPSB4,BAIAP2,TMEM164,FHL1,SYNCRIP,RGPD5,JKAMP,TMEM107,SMC2,ST6GALNAC3,FYB1,GALC,IP6K3,NEU3,TUBGCP4,MSTN,ARFIP1,SESN1,GHR,TOX3,TNRC6A,MSL3,WDFY3-AS2,ADGRA3,TDRKH,FUT10,GRIA2,CLASRP,IRAK3,UBE2QL1,ZHX1,IL6ST,ZNF678,KCND2,SYTL4,HECTD2,MBNL1,MEIS1,MN1,COL28A1,NF1,NRCAM,SETD4,OGG1,PCDH8,ENPP2,GPR85,GNG2,CCSER2,RETREG1,MAPKAP1,LRRN3,KANSL1,PRKACB,MAPK9,RELN,BCAS3,SPDL1,PTPRB,PTPRD,PTPRE,NKAIN1,RADX,MORC4,GTDC1,FIGN,ZFHX4,CCDC82,CARF,RPL15,RYR3,NCBP3,SCN7A,PEAR1,CASC3,SCAF8,KIF21A,FBXO11,FNDC3A,NLGN1,ATF7IP,TET1,RCOR3,LIMCH1,SNAP25,USP33,FNBP1,KDM3A,KDM4C,ZNF423,CLASP2,SSPO,NECAB1,SYN2,SLC37A2,FBXW11,ZEB1,TRIM2,RPGRIP1L,PCDHB7,ITGB3BP,ERCC6L2,VLDLR,RICTOR,ZNF24,LYPD6,POLR3H,LAMP5,UPF3A,MFF,STOX2,FIP1L1,UBE3B,KAT6A" MicroRNA hsa-miR-516b:mirSVR_highEffct hsa-miR-516b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.87E-67 1.61E-63 1.63E-66 1.50E-65 180 1065 "KCNH8,ACADM,PLEKHH1,BBOX1,AMPH,CDC42BPA,DPP10,PHF12,VAT1L,USP37,ATP2A2,BACH1,ADGRB3,NAE1,CACNA2D1,PRC1,ARHGEF25,CERS5,USP2,CD86,CBFA2T2,C1orf52,SRSF11,CNOT8,NDST3,NRXN3,CLCN3,FAM19A5,AKAP6,SUMF2,RTTN,CSF1,RGS6,OSBPL3,FAM169A,RIMS2,KIAA0408,KATNAL2,TCAF1,EARS2,ZNF337,B3GAT3,SV2B,CPEB2,PDCD6IP,DNM1L,AASDH,HIPK3,CNNM1,OPTN,EBI3,KMT5B,GOLGA7,RGS17,EPHB1,SRRM1,EXTL2,RACK1,ZMYND10,SUCO,FLT1,NELFCD,SMC2,ABLIM2,FYB1,GABRA3,GABRG2,GAD1,FAM120B,RAPGEF6,ACSS1,SULT1C4,RAB30,TOX3,WDFY3-AS2,GPD2,GRIA2,AP4S1,FAM107A,RASSF8,TCEAL6,MSL1,SOWAHA,TMEM240,ZNF678,KCNN3,LAMA2,HECTD2,SMAD9,MBD1,MBP,MEIS1,MEST,KCTD6,MPP2,SFR1,NEFM,NEK1,NUCB2,PCDH9,OLA1,NLGN3,SERPINI1,PCDH18,PURG,PMP22,SDK2,ING3,TATDN3,PKIA,GRAMD1C,HYDIN,SAMD9,PTPRO,ACSM5,CEP97,RASGRF2,RDX,ERI2,NUDT11,RNASEL,SUGCT,SETD5,NEK11,FBXW7,ADAL,PTGR2,NCBP3,DGLUCY,CSRNP3,GALNT10,SUPT20H,SCAF8,SH3BGR,EPN2,FAM214B,CCDC88A,SLC12A2,CXXC4,ANKRD36,PDZD2,HECW1,DBNDD2,LMO3,ELOVL4,TAF9,TAL1,ADGRL3,SATB2,RPGRIP1L,SZT2,OBSL1,FRYL,SIK3,PMS2CL,ITGB3BP,AP4E1,SLC44A1,TK2,ERCC6L2,TMPO,PIK3R5,RUNDC3B,TRO,CCDC14,LAT2,XRCC4,CELF4,AMZ1,ZNF195,PCBP1-AS1,ZFAND5,PRDM10,RNF103,MARCH8,RNF170,MSRB3,ZDHHC20,AP3B2,PRRT4" MicroRNA hsa-miR-589:mirSVR_lowEffct hsa-miR-589:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-67 1.70E-63 1.73E-66 1.59E-65 219 1549 "DGCR6,GALNT16,MTA3,AP2A2,PCDH19,RTL9,CC2D2A,SEMA6A,FAM135A,AMPH,BIN1,CCDC146,UPRT,CPNE5,DNAH17,RASL11B,ATP2B2,N4BP2L1,ATP6V0A1,BACH1,LINC00847,SYNJ1,LURAP1,CALM1,HIP1R,CBR1,CCK,SLC16A4,ZMYM4,MAGI1,TIGD7,DIS3L,NRXN3,STOML1,NGEF,FAM149A,AKAP6,SUMF2,COL9A1,SLC35F1,CREM,RBM39,GDA,SUSD5,CST3,PLCXD3,PNPLA8,CCDC144A,ARHGAP32,GAPVD1,SNPH,MATR3,DGKG,SPOCK2,DNAL1,ARMCX2,ZBTB24,TMEM130,DDX46,POM121,RHOBTB1,SV2B,DLX1,DMPK,USP3,CPEB2,DOCK2,DMTF1,SLC12A6,EDNRB,TMTC1,FAM13A,MRO,KMT5B,EGR3,EIF4G2,PLEKHA1,GPHN,RAB9B,MRPL37,RRAGB,SIRPB1,ADGRV1,FER,FOXO3,SEMA4D,TPK1,ATP6V1H,ATP2C1,ZNF605,GABBR1,FAM120B,ZNF274,GHDC,CPLX1,NEU3,SULT1C4,COPS8,MSL3,LUZP2,DCLK2,GPD1,TDRKH,GRIA2,C1QL4,LINC01089,RNF165,ZBTB49,ZBTB45,PADI2,ZHX1,FRMD3,LRRC25,LRRCC1,SCIN,ITGAM,C2CD4C,METTL21A,KCNJ16,KCNN2,LIFR,MAP2,MARK1,SHC3,MEIS1,N6AMT1,MYO6,MYO9A,HNRNPM,NEFM,NFIX,NOVA1,NTRK3,IGSF11,OCRL,GNG2,PFKFB2,FAM216A,POU6F1,PPP2R5E,PRKAB2,MASP1,PIGG,CNTLN,PTCH1,STK32A,ZIK1,PTPRD,PTPRE,PEX2,NKAIN1,RASGRF2,RDX,RFX2,RGS3,RGS12,ALG9,ARMC5,GSTCD,LRRK2,ZNF568,SCP2,FERMT1,HKDC1,WDR37,FAM81A,EPN2,WDR47,SLC11A1,INAVA,MBD5,DOK5,RBM26,NFASC,CLSTN2,CAMTA2,ITPRID2,SSTR1,ADHFE1,JMJD6,ZC3H4,PLCB1,CAMTA1,PDLIM2,FBXW11,SMG6,KLHL4,ZFP90,SZT2,PCDHGA11,HIF3A,CCDC173,DICER1,AP4E1,RGMB,ZNF346,RUNDC3B,TRPS1,RUSC1,TSN,TUBB1,RPL7L1,CLEC2L,OSBP2,USP1,CCDC14,GUSBP1,XRCC4,ZNF540,POLR3H,MEIS3,CADM2,SLC38A1,RNF103,HPS4,PARP11,UBE3B,CASC15,DPF3" MicroRNA hsa-miR-365:mirSVR_lowEffct hsa-miR-365:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-67 1.92E-63 1.95E-66 1.79E-65 193 1221 "EMILIN3,ADCY6,GALNT13,ADD2,OGT,ANK2,SUGT1P4-STRA6LP-CCDC180,DDO,USP37,SHROOM2,MPDZ,DNAJC27-AS1,PTBP2,KRIT1,DCLK1,LARGE1,CDO1,TIGD7,CCPG1,TPP1,FAM189A2,ABCG2,AKAP7,AKAP6,COL9A1,SLC4A8,ABI3BP,SMARCAL1,TOGARAM2,CREM,ENTPD4,GDA,LRIG1,SOCS5,RUBCN,HDAC4,ZNF337,KIAA0586,TMEM170A,BRINP1,SPATA2,JAKMIP2,TMEM130,USP3,MED12,DOCK2,DRP2,DNAJB6,EDNRA,EGFR,ELN,USPL1,SRRM1,CEP85L,SPEG,CDKL3,ETV1,ADGRV1,F8,TUBB3,FCGR1A,FDFT1,TMEM164,POLK,SUCO,C2orf88,EFCAB2,ATP2C1,MPP6,GALC,RAPGEF6,SIGLEC8,LRRC37A6P,TUBGCP4,SESN1,NFU1,ZNF276,TOX3,MSL3,STARD3,POLL,LUZP2,WDFY3-AS2,MCHR1,RABL2A,LINGO1,PSIP1,ARHGAP36,MSL1,METTL21A,KCNH2,KHK,SMAD1,CHIC1,LRP1B,MIA2,POC1B,ZNF862,BEX5,NFE2L2,CNOT4,OCRL,GLIPR1L2,PDE4D,PFKFB4,SEMA5B,ZNF655,PLCL1,PURG,PRIMPOL,MAPKAP1,EXOSC10,SCHIP1,POLG,TATDN3,KANSL1,PRKACB,RELN,GDPD2,BDNF-AS,EML5,PTPRN2,TMEM255A,OXR1,DPF2,RET,CCDC82,ALG9,ROBO1,KIRREL1,EPHA10,MAP6D1,ATAT1,SALL1,SEMA6D,SATB1,ATXN7,CHD9,FNDC3A,SLC2A5,BTBD3,ZFP1,CXXC4,OGDHL,INAVA,TRERF1,KDM3A,ZSWIM8,PEG10,ERBIN,NXT2,ELOVL4,CEP68,NUDT10,ADAMTS17,ANKRD12,ADGRL3,USP22,SYNE1,OBSL1,PCDHAC2,USP32P1,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,ITGB3BP,AP4E1,BHLHB9,TLR4,TMPO,BEX4,R3HDM1,RASD2,SMUG1,PDSS1,STXBP4,UGT8,CCDC14,XRCC4,ZIC2,ZNF70,ZNF74,SPIRE1,EMSY,FIP1L1,UBE3B,KAT6A,IFT88" MicroRNA hsa-miR-135a-5p:TargetScan hsa-miR-135a-5p TargetScan 3.59E-67 2.01E-63 2.03E-66 1.87E-65 137 609 "GALNT13,INTS2,MTUS1,ALCAM,APC,GAS7,ARNTL,PDE8B,NCOA1,ATP2B2,BACH1,HCN2,DST,ARHGEF7,MTMR2,LDLRAD4,PTBP2,LDB2,ARHGEF2,KCNAB3,DCLK1,LRRFIP1,DLGAP2,FOXN3,CLCN3,QKI,RAB26,ARHGEF6,PCYT1B,BAG4,C2CD2,ENTPD4,CSF1,CSNK1G3,ERC2,PLCXD3,ARHGEF4,RIMS2,ARHGAP32,HDAC4,LONRF1,DNAL1,PITPNC1,ELMSAN1,JAKMIP2,MYEF2,RAB39B,DTNA,EBF1,HIPK3,ERBB4,CEP85L,DNAJC27,EXTL2,EYA1,SCML2,FGF11,NBEA,NSG1,FUT9,MEGF11,DENND2A,B4GALNT1,RAPGEF6,CPLX2,CPLX1,GCNT2,GHR,FERMT2,PRUNE2,DIDO1,PTPRT,PSIP1,RASSF8,NEGR1,IL6ST,JAK2,KCNB1,KCND1,KCNN3,KCNQ3,GPR155,MAP4,MBNL1,MEF2C,MMP16,MYO9A,NEFM,NF1,NPTX1,PCDH9,PDE1C,PDE4A,CCSER2,DRAM2,MAPK10,DIRAS2,GDPD1,ELOVL2,PTK2,PTPRD,RAP1GDS1,ERI2,PRIMA1,ROBO1,RORB,PCMTD2,SCN2B,SEC14L1,MRAS,HSPA4L,PPM1E,FAM81A,MAPKBP1,FAM126B,IQSEC2,NXT2,RGL1,PRRC2C,DNAJC9,PLCB1,ARC,CUX2,CLASP1,C18orf54,MTMR14,CSMD1,KAT6B,KCNK12,NDRG4,EVI5,ADAMTS9,HNRNPA3,ACTR3B,MSRB3,NETO2,LAS1L" MicroRNA hsa-miR-135b-5p:TargetScan hsa-miR-135b-5p TargetScan 3.59E-67 2.01E-63 2.03E-66 1.87E-65 137 609 "GALNT13,INTS2,MTUS1,ALCAM,APC,GAS7,ARNTL,PDE8B,NCOA1,ATP2B2,BACH1,HCN2,DST,ARHGEF7,MTMR2,LDLRAD4,PTBP2,LDB2,ARHGEF2,KCNAB3,DCLK1,LRRFIP1,DLGAP2,FOXN3,CLCN3,QKI,RAB26,ARHGEF6,PCYT1B,BAG4,C2CD2,ENTPD4,CSF1,CSNK1G3,ERC2,PLCXD3,ARHGEF4,RIMS2,ARHGAP32,HDAC4,LONRF1,DNAL1,PITPNC1,ELMSAN1,JAKMIP2,MYEF2,RAB39B,DTNA,EBF1,HIPK3,ERBB4,CEP85L,DNAJC27,EXTL2,EYA1,SCML2,FGF11,NBEA,NSG1,FUT9,MEGF11,DENND2A,B4GALNT1,RAPGEF6,CPLX2,CPLX1,GCNT2,GHR,FERMT2,PRUNE2,DIDO1,PTPRT,PSIP1,RASSF8,NEGR1,IL6ST,JAK2,KCNB1,KCND1,KCNN3,KCNQ3,GPR155,MAP4,MBNL1,MEF2C,MMP16,MYO9A,NEFM,NF1,NPTX1,PCDH9,PDE1C,PDE4A,CCSER2,DRAM2,MAPK10,DIRAS2,GDPD1,ELOVL2,PTK2,PTPRD,RAP1GDS1,ERI2,PRIMA1,ROBO1,RORB,PCMTD2,SCN2B,SEC14L1,MRAS,HSPA4L,PPM1E,FAM81A,MAPKBP1,FAM126B,IQSEC2,NXT2,RGL1,PRRC2C,DNAJC9,PLCB1,ARC,CUX2,CLASP1,C18orf54,MTMR14,CSMD1,KAT6B,KCNK12,NDRG4,EVI5,ADAMTS9,HNRNPA3,ACTR3B,MSRB3,NETO2,LAS1L" MicroRNA hsa-miR-548g:PITA hsa-miR-548g:PITA_TOP PITA 4.84E-67 2.71E-63 2.74E-66 2.52E-65 141 649 "KCNH8,ACTN1,FMNL2,USP31,PWWP2A,LRFN2,HECW2,PCDH19,ALCAM,CDC42BPA,APAF1,TMEFF1,CDK13,NCOA1,SLC4A4,ATP2A2,SYNJ1,FUBP1,CACNA1I,LDLRAD4,CACNB4,CALB1,CALM1,CLDN10,CLGN,SRSF11,SOCS6,LHX2,FAM19A5,QKI,CNN3,CLOCK,CREM,CRMP1,CSNK1G3,PLCXD3,GAPVD1,LONRF1,MATR3,DUSP9,ABCC5,EDN3,KMT5B,PLEKHA1,RGS17,STARD3NL,TAOK3,SUCO,FOXF2,FUT9,AHDC1,PCDH17,TCERG1,TNRC6A,FERMT2,GPT2,GRB10,GRIA2,PTPRT,FAM19A2,RNF165,PSIP1,ADAMTS6,MAP4K5,ZHX1,BACH2,HLF,NEGR1,AGFG1,DHX35,MARK1,MAT2A,MEIS1,MID1,AFF1,MXI1,MYO5A,NEXMIF,NEFM,NRCAM,KSR2,PCSK1,PIK3R1,RETREG1,KCTD15,PPARA,PPP2R5E,PPP3CA,KANSL1,RELN,PTCH1,PTPRD,TMEM255A,FIGN,ZFHX4,ROBO2,RORB,FBXW7,CSRNP3,TRA2B,CPEB3,CHD9,FBXO11,FNDC3A,PPP4R3A,EPN2,WDR47,CCDC88A,ATF7IP,CPEB4,TMCC1,SOX11,LMO3,SS18,STAU1,ANKRD12,FBXW11,TCF12,SYNE1,DOCK9,TMEM121,ERCC6L2,R3HDM1,RPRM,EIF4ENIF1,FLRT2,PCDH20,ZBTB14,ZNF711,LYPD6,EMSY,STOX2,PRDM8,NAV3,SLC17A7,PCBP4,HNRNPA3,PHTF2,JMJD1C,SOCS4,JPH3" MicroRNA hsa-miR-144:PITA hsa-miR-144:PITA_TOP PITA 5.57E-67 3.11E-63 3.15E-66 2.90E-65 135 592 "CCDC85A,AXIN2,USP31,PCDH19,TAOK1,SEMA6A,ALCAM,CDC14B,CADPS,MARCH3,ZSCAN18,ATP2B2,NRP2,JAZF1,LDLRAD4,CALB1,USP6,CDH2,CFL2,SOCS6,CHN2,B4GALT6,LHX2,QKI,CNN3,CNR1,PPP1R16B,PUM1,USP6NL,DOCK4,GAPVD1,MYEF2,ALKBH8,RHOBTB1,SNAP91,DMD,CPEB2,MBNL2,GOLGA7,EIF4G2,RGS17,CALCRL,EPB41,SRRM1,ACSL4,ST3GAL6,MED12L,DCTN2,CAMKK2,KHDRBS3,ST6GALNAC3,AHDC1,GFRA2,PPARGC1A,TNRC6A,LUZP2,LPAR4,ZHX1,BACH2,MIER3,HSF2,ZIC5,SLC6A17,JAK2,KCND2,LIFR,NCOA7,SMAD1,MBNL1,MEIS1,MEIS2,KITLG,MITF,MSI1,MYO5A,NEXMIF,MYT1,ZC3H12B,NF1,NFE2L2,NPTX1,CNTN3,PDE4D,PIK3C2A,PCDH18,LRP12,PPARA,PRKACB,PKIA,CNTLN,OXR1,ZFHX4,ZNF532,SETD5,SALL1,SEMA6D,SCP2,SMPD3,CPEB3,FNDC3A,SEPHS1,CCDC88A,SLC12A2,SNCA,FAM126B,SP4,ARHGAP26,CDK19,CAMTA2,SS18,ST5,STAU1,RGL1,ZC3H4,ADAMTS17,ANKRD28,FAM208A,FBXW11,TRIM2,RPGRIP1L,PCDHB7,TEK,DICER1,SGK3,PCDH20,ZBTB38,MFF,CADM2,SLC38A1,NAV3,WNK3,KAT6A,PHTF2,NETO2,SENP7" MicroRNA hsa-miR-30c-2*:mirSVR_highEffct hsa-miR-30c-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.37E-67 5.24E-63 5.29E-66 4.87E-65 184 1120 "ADD2,PWWP2A,KCTD16,WDR35,AK2,ALCAM,MARCH4,PCDH10,BIN1,LRFN1,CDC42BPA,TNRC6C,SEMA4G,ADAM15,SEC11C,ARHGEF7,JAZF1,VXN,RUNX1T1,LDB2,CD86,ARHGEF2,CHN2,TAOK2,AKAP7,IQCK,FAM149A,AKAP6,COL9A3,CREM,HAPLN1,LRRC3B,ERC2,MYADM,DCAF8,MAML1,ZC3H11A,RHOBTB1,WDR20,GRIN3A,SLC29A4,SHANK1,DTNA,MAMLD1,DNM1L,AASDH,WDPCP,HIPK3,EGFR,MBNL2,KCTD3,EPB41,EPHB1,SIRPB1,ABCA8,DLC1,RACK1,PPP1R1B,FGF13,FHL1,PDLIM5,USP21,FYB1,GABBR1,ERAP1,DISC1,SRRM4,ALDH1L1,TUBGCP4,GGT7,MALT1,LOXL3,MCHR1,ATP2B1-AS1,GRIA2,PLCD4,RABL2A,SOX21,RNFT2,ADAMTS6,NXPH3,FRMD5,ARHGAP36,MIER3,AGBL5,HNF4G,ZDHHC15,LRRCC1,SCIN,MBNL1,MT1M,P2RY13,NEFM,NF1,TBC1D25,IGSF11,OPA1,CDK18,GNG2,NLGN3,PLCB2,PLEC,MTRF1L,PURG,RELN,CNTLN,TMEM260,PTPRH,PTPRO,RAP1GDS1,ZCWPW1,ZNF493,HKR1,GTDC1,EXD2,KIRREL1,SCN8A,KIF16B,CPEB3,FNDC3A,SLC8A1,ATF7IP,ZKSCAN3,SMARCC2,SNCA,MBD5,CABCOCO1,DOP1A,ZSWIM8,SPTAN1,DDN,ATP10B,CLASP2,ZC4H2,NKAIN2,STAU1,SEPT8,SULF2,SYNE2,SYP,TACR1,KLHL4,RPGRIP1L,OBSL1,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,CYB561A3,C18orf54,ITGB3BP,AKTIP,SLC44A1,TIAM1,ERCC6L2,TPM1,SMUG1,KCNE5,PRR18,TUBB1,UBE3A,FLRT2,PLEKHH2,KLC2,GUSBP1,ZIC1,ZNF19,SPIRE1,FTSJ1,MEIS3,PRTFDC1,HPS4,SLC17A7,UBE3B,ACTR3B,KLHDC1,NETO2,FAM198A" MicroRNA hsa-miR-328:mirSVR_lowEffct hsa-miR-328:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-66 6.13E-63 6.18E-66 5.69E-65 200 1316 "KCNH8,ACADM,GALNT13,ADORA2A,MTA3,PCDH19,KCTD16,CCDC146,SUGT1P4-STRA6LP-CCDC180,APBA2,EPB41L5,UPRT,USP37,ASGR1,RASL11B,N4BP2L1,NRP2,CFLAR,KSR1,BMPR1B,SYNJ1,ARHGEF7,CACNA1G,HAP1,CERS5,ARHGEF1,CD38,AP4M1,MAGI1,NUMBL,TAOK2,RAB33A,PLAA,CNR1,CABP1,C2CD2,SH2B1,SNCAIP,CSF2RA,PPP1R16B,BOC,ARHGAP32,KATNAL2,ARHGAP24,ZFYVE16,DAPK1,SPOCK2,IP6K1,GIT2,ARMCX4,YTHDC1,GRIN3A,NYAP1,CD99L2,DOCK2,PDCD6IP,DNAJB6,RASGRP1,YAF2,SUGP2,TNK2,ENO2,F5,STRADA,KAT8,SPSB4,BAIAP2,TMEM164,FHL1,MEX3B,ANKFY1,HHIPL1,DOT1L,DISC1,ALDH1L1,TUBGCP4,TUBA8,STARD3,GRB10,GRIA2,GRIK5,BTN2A1,CLASRP,ATXN2L,MIER3,ELOVL5,GABARAPL2,NEGR1,CPT1C,KNDC1,SCIN,ITGA7,KCNK3,ZFYVE27,MAP4,MBP,MEIS2,SCAMP5,XRRA1,MMP16,MN1,MPP2,PTOV1,LYRM9,MYO9A,ZC3H12B,NFYA,NNAT,NME4,VWA2,SLC11A2,NTRK2,TBC1D25,OPRL1,CLDN11,NLE1,PLXNB1,PNMA3,LRP12,RETREG2,PILRA,GRAMD1C,TMEM104,TMEM260,PTPRO,TUG1,CEP97,SLC25A48,FAM66C,MSANTD2,GTDC1,SETD5,CARF,GSTCD,CYB561D1,CCDC102B,EPHA10,RPL15,BAALC,GLDN,TCP11L1,MAP6D1,MEG3,ST6GALNAC6,NCBP3,MAPK12,SCN2B,FERMT1,ASAP3,WDR37,FAM214B,CCDC88A,SLC22A4,ABTB1,OGDHL,INTS9,RCOR3,SNRPN,ZSWIM8,PEG10,IQSEC2,TSPYL2,NFASC,LHPP,ATP10B,SEPT8,PHLDB1,SEPT3,TACC1,AGTPBP1,ZEB1,HIF3A,ARL10,ENHO,TIAM1,LRRC8A,TMPO,PIK3R5,RGMB,SYNPO2,NEIL2,PPIL6,TTTY15,UGT8,MTCH1,CCDC136,CLIP2,LAT2,ZNF781,ZNF23,TRIM9,SPIRE1,DHX33,SEMA3B,GAL3ST3,URM1,SLC17A7,CASC15,FAM219B,LAS1L" MicroRNA hsa-miR-100*:mirSVR_highEffct hsa-miR-100*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-66 1.12E-62 1.12E-65 1.03E-64 164 896 "RALGAPA1,XKR4,AXIN2,PWWP2A,BEND6,MARCH4,SEMA7A,LCORL,PDE8B,ZBTB10,BACH1,PTBP2,SLC25A14,CAST,LRBA,L3MBTL4,SRSF11,TAOK2,CLTC,HECTD1,CNN3,IQCK,PCYT1B,WHRN,ABI3BP,AHCTF1,TOGARAM2,CNRIP1,CRMP1,RNF14,LRRC3B,SOCS5,FAM169A,ERC2,PHF14,ARHGAP24,ZNF337,KIAA0586,KCTD8,ARMCX4,HEPH,DDX46,DLX1,USP3,MED12,CDON,DPH1,DTNA,ABCC5,EBF1,SNX29,MRNIP,CALCRL,DENND4A,SCML2,FGF14,SUCO,SYNCRIP,NBEA,APOPT1,UFM1,SARAF,OGA,FAM120B,SRCAP,GGTA1P,GHR,PPARGC1A,SPIN1,GLUL,TDRKH,FUT10,GRIA2,PLCD4,PSIP1,PACSIN2,DHX35,ZNF678,ITGAM,JAK2,SYTL4,HECTD2,NCOA7,PACRG,ZFYVE27,MEIS1,SRSF12,AFDN,ZNF680,THYN1,LAYN,MYO9A,NCAM2,IDNK,NEK1,NF1,VWA2,GLIPR1L2,PCDH9,PCSK1,CYTL1,PCDH18,PRIMPOL,EXOSC10,SH3KBP1,MINDY2,PSMA6,PTCH1,PTPRD,EML5,TMEM255A,OXR1,RASGRF1,RASGRF2,RBBP6,GTDC1,RFX3,ZFHX4,TMLHE,EXD2,CARF,RORB,PCMTD2,CCDC102B,RPL15,BAALC,LRRK2,SCN7A,TRA2B,FERMT1,SHMT2,CHD9,FBXO11,R3HDM2,PREX2,NAPB,ATF7IP,TRERF1,SOX3,MCF2L2,POGZ,NEK4,ADHFE1,SYPL1,DNMBP,TCEA1,SATB2,TCF12,BEX4,C9orf85,RGMB,VLDLR,CLDND1,SMARCAD1,EMSY,STOX2,HPS4,RTN4,PHTF2,ADAMTSL3,MSRB3,FXR1,IFT88,NETO1" MicroRNA hsa-miR-450b-5p:PITA hsa-miR-450b-5p:PITA_TOP PITA 2.11E-66 1.18E-62 1.19E-65 1.09E-64 135 598 "XKR4,ELFN2,USP31,SLC24A4,PCDH19,OSBPL1A,TAOK1,SPOP,TMEFF1,ZBTB10,DPY19L3,JAZF1,LDLRAD4,CALB1,CALM1,CDH2,KCNAB3,CFL2,FOXN3,SOCS6,CLCN3,FAM189A2,FAM19A5,QKI,ARHGEF6,MAGED1,MYRIP,ZNF521,PHF14,RIMS2,LONRF1,IST1,SPOCK3,SEC16A,DMD,MED12,CPEB2,GOLT1B,EBF1,KLHL5,KMT5B,EPHB1,GPHN,SRRM1,ERBB2,ACSL4,MEX3B,AGAP2,AFF2,NBEA,PCDH17,GGT7,DHRS4,TNRC6A,TMEM121B,SOX21,ADAMTS6,MAP4K5,PADI2,BACH2,MIER3,CELF5,SMAP1,IGF1,STMN1,MAP2,MBNL1,MEF2C,KITLG,SAMD5,NFE2L2,OCRL,CNTN3,PCDH8,PDE4B,GPR85,PIK3C2A,PLCL1,POLG,PPP2R5E,PPP3CA,WBP1L,PTX3,TMEM255A,MSANTD2,FIGN,PBRM1,ROBO1,FBXW7,HUNK,KCNIP3,SALL1,CSRNP3,KIF21A,CPEB3,TRIM67,CPEB4,GKAP1,RCOR3,SNCA,PDZRN3,SOX11,SP4,LARP4,NKAIN2,TTBK2,RHBDL3,SYPL1,ANKRD28,ANKRD12,CAMTA1,ADGRL3,DMXL2,SATB2,TRIM2,RPGRIP1L,DOCK9,ZFPM2,KAT6B,PDSS1,TRPS1,SGK3,VLDLR,ZNF711,MICU3,ZBTB38,ZFAND5,EMSY,MFF,EVI5,TMEM178A,NAV3,RTN4,SMIM8,HNRNPA3" MicroRNA hsa-miR-520f:mirSVR_highEffct hsa-miR-520f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.04E-66 1.70E-62 1.71E-65 1.57E-64 193 1237 "KCNH8,MTUS1,HECW2,AK2,HFM1,ZFAT,ANK2,PHF12,EPB41L5,RASL11B,TMEM108,DPY19L3,BACH1,SEC11C,CFLAR,ST3GAL5,MTMR3,JAZF1,WASF1,CALB2,PTBP2,VXN,PRC1,METTL6,CBFA2T2,CDC25B,CDH2,MAGI1,CLGN,CFL2,RCBTB2,ABCG2,MAP4K4,ARMC8,AKAP6,LETMD1,AKAP5,IGDCC3,CNRIP1,ZNF385A,SOCS5,PHF14,GREB1,USP6NL,CCDC144A,DBI,YTHDC1,ZNF804A,ZC3H11A,RHOBTB1,HS3ST2,DTNA,FARSB,ABCC5,GOLT1B,EDNRB,ANKRD46,MBNL2,KMT5B,GOLGA7,IRAK4,EMX2,IGSF6,CDKL3,DNAJC27,RPS6KC1,FER,MED12L,POLK,WDR83,HVCN1,ATP2C1,FYB1,IP6K3,ERAP1,SIGLEC8,TUBGCP4,GGTA1P,TNRC6A,MAP7D2,GPD2,GPR34,FAM222A,ZHX1,HNMT,SMAP1,MSL1,RBPJ,IL6ST,KCNN3,LIG4,SYTL4,MARK1,MEF2C,SRSF12,KITLG,COMMD5,MYO9A,NACA,NOVA1,NPTX2,NRCAM,TBC1D25,GPR137C,CNTN3,PCDH9,PRTG,CCSER2,MTRF1L,PRIMPOL,LRP12,EXOSC10,ING3,SEPT4,TATDN3,PKIA,RELN,TMEM260,STK32A,PTPRE,CEP97,KHDRBS2,RDX,RET,FIGN,RFX3,RGS12,RIC8B,RNH1,SETD5,GSTCD,ATAT1,TNFRSF19,FBXO11,FNDC3A,WDR37,PPP4R3A,TET1,SMARCC2,RCOR3,RBM34,TRERF1,HECW1,PEG10,IQSEC2,CDK19,ZBTB43,RBM26,LMO3,ATP10B,POGZ,NXT2,RGL1,STXBP1,KLHL7,DNAJC9,SYT1,DNMBP,ADGRL3,TBCEL,FBXW11,TCEA1,ZFP90,CUX2,ZEB1,SZT2,PCDHB9,USP32P1,ZFPM2,ITGB3BP,AP4E1,RGMB,PPIL6,TUBB1,UGT8,TOM1L2,VLDLR,PCDH20,ZNF711,LYPD6,CELF4,ZNF154,LAMP5,PRTFDC1,PRDM8,PRDM10,FAM13C,DOCK8,ADAMTSL3,NLRP3,MSRB3,ZDHHC20,IFT88" MicroRNA hsa-miR-92a:mirSVR_highEffct hsa-miR-92a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.20E-66 1.79E-62 1.80E-65 1.65E-64 166 921 "SYN3,NCKAP5,TMCC3,KIAA1211,MARCH4,FAM135A,PITPNM2,DPP10,ATP2A2,ADAM23,ADGRB3,MPDZ,HCN2,SYNJ1,CACNA1I,CA8,KALRN,CAMK2A,MTMR7,SOCS6,NDST3,NRXN3,HECTD1,CNRIP1,FAM171B,CRHBP,VCAN,SOCS5,FAM169A,SLITRK5,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,PLPPR4,SACS,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,FHL1,POLK,ATP13A4,SLC37A3,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,IQGAP2,GHR,SPIN1,GLYR1,GPD2,LPAR4,TPPP,DIDO1,HAS2,MIER3,HNMT,MSL1,RBPJ,SLC6A17,C2CD4C,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,GPR137C,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,TRHDE,STRN3,ING3,CEP41,PTPRD,PTPRO,TMEM255A,RAD51D,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,FNIP1,SUPT20H,TRA2B,CPEB3,MYO18A,CHD9,CNKSR2,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PDZD2,MYCBP2,TEX2,PBLD,ITPRID2,ELOVL4,RGL1,SYN2,SYPL1,SYT1,CAMTA1,SATB2,SYNE1,DOCK9,SIK3,SYNPO2,TRIO,SGK3,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,MFF,EVI5,RNF103,NAV3,RGS7BP,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-218-1*:mirSVR_lowEffct hsa-miR-218-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.28E-66 1.84E-62 1.84E-65 1.70E-64 208 1426 "SYN3,KLHL32,BRAP,SLC24A4,PCDH19,AGT,CC2D2A,HFM1,AMPD2,DPP10,MAP4K3,PHF12,VAT1L,SHROOM2,RGS20,DNAH17,CHRD,ADAM23,RGS9,SYNJ2,ARHGEF7,SCAPER,CASTOR3,LDLRAD4,CACNA1A,CACNA1B,CACNB4,VXN,CAST,HIP1R,NFS1,USP6,NUMBL,CHN2,RAB28,NRXN3,IQCK,FAM149A,CABP1,SLC35F1,ENTPD4,RBM39,GDA,CSF2RA,ARHGEF10,CSNK1E,VCAN,VAC14-AS1,UBXN2A,PNPLA8,SEC14L5,MATR3,IST1,SCRN1,ARMCX2,DGCR5,GUCD1,FAM107B,ZNF582-AS1,EXOG,RAB39B,HS3ST2,CDON,DPYSL2,DTNA,DNAJB6,ABCC5,DNM1L,APH1A,KCTD3,MRNIP,TUBD1,NCALD,TUBB3,SCML2,FCGRT,FKTN,STRADA,SLC9B2,FGF11,PCYOX1,SEMA4D,ERGIC3,STAU2,OGA,GAD1,RAPGEF6,DISC1,CPLX2,KIAA1841,ADAM28,PPARGC1A,SPIN1,PRUNE2,C1QL4,GRM8,LINC01089,BTN2A1,RNF165,SOX21,FRMD5,TNFAIP8L3,MIER3,NKD1,IL6ST,LSS,PIK3AP1,MARK1,MEIS2,SRSF12,XRRA1,HS6ST3,MYT1,TCEAL5,NME4,CLDN11,P2RX7,PCSK1,PIK3C2A,TMIE,PIK3R1,XRN1,PLIN1,STRN3,LRP12,ING3,PRKACB,CEP41,PRPH,DEF8,SPDL1,TMEM260,TTC13,TUG1,USP47,ERI2,MRPS18A,YY1AP1,RPL15,ZNF671,ABCA11P,HSD11B1L,ATAT1,ZNF354C,ATXN2,ZFP30,FAM102A,KIF16B,FNDC3A,DZIP1,SLA,SLC4A3,PPP4R3A,PKNOX2,BTBD7,ATF7IP,TET1,CPEB4,GKAP1,MYH15,KIF13A,SNRPN,PDZRN3,TRERF1,FNBP1,PEG10,TSPYL2,ITPRID2,STAU1,PHLDB1,TMEM150C,SYPL1,ZEB1,TPCN2,NAT16,DOCK9,USP32P1,HIF3A,CYB561A3,RNF216P1,FAM200B,ZNF106,MTMR14,RELL2,ACTR6,R3HDM1,WBP2,METTL3,ZKSCAN5,CLDND1,ZNF24,KCNT2,LYPD6,ZNF154,FSTL5,SLC30A4,EVI5,ADAMTS9,WNK2,RGS7BP,DOCK8,UBE3B,KAT6A,PHTF2,RSPRY1,FRMD6,DPF3,LAS1L" MicroRNA hsa-miR-1208:mirSVR_highEffct hsa-miR-1208:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.45E-66 2.49E-62 2.50E-65 2.30E-64 178 1060 "RALGAPA1,KCNH8,SYN3,CLK4,ABHD6,ADD2,PWWP2A,PTCHD1,BEND6,AP2A2,ALCAM,LTBP4,FAM135A,OGT,N4BP2L1,DPY19L3,SEC11C,PROM1,FUBP1,CARS,CCNH,CDH2,CHN1,CHN2,B4GALT6,TPP1,C4orf33,HECTD1,MAP4K4,ARHGEF6,ARMC8,AKAP6,SMARCAL1,RTTN,FAM171B,PREPL,SIPA1L1,SOCS5,ERC2,USP6NL,ZNF337,C2CD2L,RHOBTB1,SPOCK3,EXOG,CPEB2,CASP8AP2,DPP6,DPYSL2,DTNA,FAM78B,MAMLD1,ABCC5,HIPK3,OPTN,EGFR,ENO2,EPHB1,ADGRV1,ARMCX1,ZNF461,ST3GAL6,CEP78,FDFT1,FGF13,FGFR1,FHL1,NOP56,JKAMP,NBEA,ST6GALNAC3,GABRG2,ZNF274,SULT1C4,GLI2,TOX3,CNTRL,GRIK4,SOX21,GUCY1B1,RASSF8,FRMD3,HNF4G,HNMT,IGFBPL1,ZNF491,FAM69A,INPP5B,KCND2,LAMP2,PAXBP1,MAT2A,TM6SF1,MEIS1,XRRA1,NFE2L2,CLDN11,GPR137C,PDCD2,ZDHHC8,SERPINI1,STRN3,ING3,PPM1B,RELN,CNTLN,PTCH1,ELOVL2,PPP2R3C,SH3TC2,RASGRF2,RADX,ROBO2,BAALC,NCBP3,SEMA6D,SATB1,ATXN7,ARX,SHMT2,FNDC3A,BTBD3,CCDC88A,BTBD7,CPEB4,RCOR3,LIMCH1,SNAP25,MBD5,ZC3H13,ATP10B,ITPRID2,ZC4H2,STAU1,ZSCAN29,RGL1,DIP2A,NECAB1,SYNE2,VPS13A,PLCB1,COBL,ADGRL3,CUX2,ZEB1,SYNE1,ZMAT3,MTMR14,TLR4,ERCC6L2,TMPO,RIMBP2,RGMB,ANKRD20A2,SLC35A4,UBE3A,GORASP1,WIPF1,WRN,LGI4,ZNF19,MKRN3,LYPD6,TCEAL7,ZBTB38,ANKS1B,MFF,CADM2,NT5M,LINC02210,NAV3,PPP1R3F,FAM13C,ST7,PHTF2,FRMD6,ST8SIA2,ZNF30" MicroRNA hsa-miR-146a:mirSVR_highEffct hsa-miR-146a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.64E-66 2.59E-62 2.60E-65 2.39E-64 176 1037 "KCNH8,CLK4,KIAA1211,ESYT2,ADRB2,DPY19L2P4,INTS2,RTL9,KIAA1324,CC2D2A,SPOP,FAM135A,AMPH,LCORL,PPFIA3,CASK,NCOA1,NUMB,NRP2,BMPR1B,SYNJ2,JAZF1,GYG2,RAB29,LURAP1,KALRN,HIP1R,RUNX1T1,CCK,USP6,USP2,DIS3L,CFL2,PPT2,ABCG2,ARMC8,COL4A5,ANKRD35,COL9A1,SLC4A8,ABI3BP,GDA,SEC24C,APPL1,PHF14,PUM1,CCDC144A,DOCK4,ZBTB24,C2CD2L,DMD,USP3,NR1D2,CDON,ACOT8,DTNA,ABCC5,EDNRB,FCF1,RASGRP1,FRY,YAF2,PHF20L1,GOLGA7,KCTD3,EIF4G2,TUBD1,MRPL37,SIRPB1,CLVS1,SH3YL1,SCML2,GORAB,SLC9B2,AMOTL2,FHL1,MEX3B,RGPD5,STAMBP,CAMKK2,CSPG5,MSANTD4,SARAF,FYB1,MTHFD2,MSTN,MALT1,RUNDC3A,COPS8,SPIN1,KDM2B,TDRKH,PCLO,STMN2,CIT,HAS2,HMGCL,ZNF181,ITPKB,KCNJ16,STXBP5,MARK1,SRSF12,MID1,MMP16,ZNF92,ZC3H12B,NOVA1,CLDN11,PURG,SCHIP1,DIRAS2,DCHS2,BCAS3,TMEM260,STK32A,PTPRE,PID1,USP47,ZNF493,RBBP6,ERI2,RIC8B,ZFHX4,ZNF532,CARF,PNMA8A,ROBO1,SNX22,MCMBP,ADAL,ZNF331,DGLUCY,SH3BGR,FERMT1,WDR47,CCDC88A,DMRTC1,TTC17,USP33,PDZD2,PEG10,DBNDD2,PBLD,CLASP2,ZC4H2,ZSCAN29,SYNE2,SYT1,ANKRD28,ANKRD12,ADGRL3,KLHL4,RPGRIP1L,DOCK9,SLC19A3,ARL10,ERCC6L2,TPM1,RGMB,RUNDC3B,PPIL6,ZKSCAN5,TUBB1,PLEKHH2,ZIC1,ZNF32,TRIM9,ZNF540,ZNF138,ZNF142,CADM2,PLSCR4,SMIM8,PHTF2,FXR1" MicroRNA hsa-miR-19b:PITA hsa-miR-19b:PITA_TOP PITA 4.90E-66 2.74E-62 2.74E-65 2.52E-64 149 741 "ABR,ASIC1,ACTN1,HECW2,SRPX,PITPNM2,CDC42BPA,LRCH2,MAP4K3,CDK13,STK33,ZBTB10,CCAR2,ATP2B2,NRP2,ST3GAL5,JAZF1,THSD7A,CALM1,CAST,USP6,SEPT7,ZMYM4,EVI5L,ZNF445,CCPG1,CFL2,PLAA,CLTC,QKI,CNGA3,CNTFR,ZNF521,SLC35F1,CLOCK,CRMP1,GDA,CS,SOCS5,APPL1,PPP6R2,SNPH,DCAF8,HDAC4,LONRF1,MAML1,DBN1,ZNF804A,ARRDC4,HIPK3,MBNL2,EGR3,PLXNC1,EMX2,ERBB4,NCALD,ETV1,ACSL4,PTK2B,SCML2,DLC1,MED12L,OLFM1,FOXF2,FLNC,NBEA,FUT9,ARFIP1,TNRC6A,KDM2B,GRB10,CIT,SOX21,MIER3,HLF,ELOVL5,IGF1,ZIC5,KCND2,KIT,MBNL1,CHIC1,MID1,AFF1,MYCN,NEXMIF,TBC1D25,PDE1C,PFKFB3,PIK3C2A,CCSER2,LRP12,PPP2R5E,VSTM2L,PSD,WBP1L,MTMR10,PTPRD,PTPRG,RBBP8,ROBO2,CLIP1,RTN1,SGK1,FAM102A,CPEB3,FNDC3A,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,CPEB4,RCOR3,CDK19,RGL1,PLCB1,ARC,SYN2,SYT1,ANKRD12,CAMTA1,FBXW11,TCF4,SIN3B,DMXL2,TRIM2,DICER1,ZFPM2,RIMBP2,CSMD1,WBP2,STXBP4,TRPS1,TSC1,FAM155A,TOM1L2,ZBTB14,ZNF711,SPHK2,REEP1,DPYSL5,MAP3K12,MFF,NAV3,PDSS2,RGS7BP,PHTF2,FXR1" MicroRNA hsa-miR-19a:PITA hsa-miR-19a:PITA_TOP PITA 4.90E-66 2.74E-62 2.74E-65 2.52E-64 149 741 "ABR,ASIC1,ACTN1,HECW2,SRPX,PITPNM2,CDC42BPA,LRCH2,MAP4K3,CDK13,STK33,ZBTB10,CCAR2,ATP2B2,NRP2,ST3GAL5,JAZF1,THSD7A,CALM1,CAST,USP6,SEPT7,ZMYM4,EVI5L,ZNF445,CCPG1,CFL2,PLAA,CLTC,QKI,CNGA3,CNTFR,ZNF521,SLC35F1,CLOCK,CRMP1,GDA,CS,SOCS5,APPL1,PPP6R2,SNPH,DCAF8,HDAC4,LONRF1,MAML1,DBN1,ZNF804A,ARRDC4,HIPK3,MBNL2,EGR3,PLXNC1,EMX2,ERBB4,NCALD,ETV1,ACSL4,PTK2B,SCML2,DLC1,MED12L,OLFM1,FOXF2,FLNC,NBEA,FUT9,ARFIP1,TNRC6A,KDM2B,GRB10,CIT,SOX21,MIER3,HLF,ELOVL5,IGF1,ZIC5,KCND2,KIT,MBNL1,CHIC1,MID1,AFF1,MYCN,NEXMIF,TBC1D25,PDE1C,PFKFB3,PIK3C2A,CCSER2,LRP12,PPP2R5E,VSTM2L,PSD,WBP1L,MTMR10,PTPRD,PTPRG,RBBP8,ROBO2,CLIP1,RTN1,SGK1,FAM102A,CPEB3,FNDC3A,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,CPEB4,RCOR3,CDK19,RGL1,PLCB1,ARC,SYN2,SYT1,ANKRD12,CAMTA1,FBXW11,TCF4,SIN3B,DMXL2,TRIM2,DICER1,ZFPM2,RIMBP2,CSMD1,WBP2,STXBP4,TRPS1,TSC1,FAM155A,TOM1L2,ZBTB14,ZNF711,SPHK2,REEP1,DPYSL5,MAP3K12,MFF,NAV3,PDSS2,RGS7BP,PHTF2,FXR1" MicroRNA hsa-miR-648:mirSVR_lowEffct hsa-miR-648:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.88E-66 3.29E-62 3.28E-65 3.02E-64 196 1279 "DGCR6,CLK4,ACTN1,TMEM132B,SLC24A4,CASKIN1,KIAA1324,WDR35,OSBPL8,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,VAT1L,CDK10,CASK,SPTBN4,CADPS,STK33,CCDC74A,INSYN2B,ZNF583,ATP6V0A1,ADAM15,ADGRB2,BARD1,BBS2,BCL7A,BCS1L,CFLAR,ST3GAL5,CA4,P2RX6,CD86,LRRFIP1,CACNA2D2,CPNE6,NRXN3,ABCG2,SRP14-AS1,IGLON5,FHL5,FAM149A,AKAP6,ABI3BP,CLOCK,CDC42BPB,CREM,GDA,CS,SEC24C,ARHGEF10,LIN54,DGKB,PABPC5,ARMCX4,YTHDC1,HEPH,TMEM130,SPOCK3,SEC16A,USP3,CASP8AP2,PDCD6IP,EDN1,MBNL2,PLEKHA1,TNK2,EYA1,F5,CLVS1,ZNF461,TAOK3,RACK1,KAT8,FGF14,SYNCRIP,FLT1,JKAMP,TVP23A,ADAM28,RUNDC3A,RNPS1,TOX3,PLPP7,GSTM5,BVES,BACH2,ACOT7,NEGR1,EID2B,INPP5B,KCNJ16,KIT,KTN1,PAXBP1,SYTL4,MAN2A2,MAP6,MBNL1,ADAM11,LRP1B,MEIS2,POC1B,AFF1,MMP16,SAMD5,MSR1,BEX5,ZC3H12B,CCDC13,NINJ2,NME4,SLC11A2,NTRK2,PDCD2,PFKFB2,SERPINI1,SNX10,NLE1,MAPK4,HYDIN,MASP1,SNRK,QRICH1,WDR25,BDNF-AS,PTK2,TMEM260,RASGRF2,GTDC1,CARF,ROBO1,YY1AP1,RPL15,ST6GALNAC6,ZNF331,ATXN7,PRCD,KIF21A,ARX,SLC4A3,ARHGEF40,SLC11A1,CDK5RAP2,SNAP25,CMTR2,TMCC1,MYO16,ZSWIM8,MYCBP2,RBM26,DDN,NFASC,TROVE2,DIP2A,KANK1,SYPL1,SYT1,SYT5,EXOC7,FBXW11,MGRN1,SIN3B,TRIM2,NAT16,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PRRT1,TPM1,RGMB,SYNPO2,TSN,TUBB2A,FLRT2,LMF1,CLDND1,GUSBP1,ZNF540,MKRN3,ZNF138,LAMP5,PRTFDC1,MDH1B,FAM13C,PHTF2,ADAMTSL3,TIGD6,RNF170,TTC7A,SPATA13" MicroRNA hsa-miR-3144-5p:mirSVR_lowEffct hsa-miR-3144-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.92E-66 3.31E-62 3.31E-65 3.04E-64 173 1004 "ASPHD1,EMILIN3,TMCC3,RNF157,ADD1,PCDH10,UNC79,LRFN1,SPTBN4,ARNTL,PDE8B,PCDHGB4,CHID1,DNAJC27-AS1,CACNB4,CALB1,CALB2,CABP7,KALRN,ZMYM4,NOG,NDST3,EPS15L1,NRXN3,PPT2,STOML1,FHL5,IQCK,LETMD1,TBPL1,TOGARAM2,MYRIP,CLIP3,SOCS5,RUBCN,ZNF337,SPOCK2,KIAA0319,ZC3H11A,SV2B,TOM1,EDNRA,CNNM1,EIF4G2,REEP2,CORO2B,FGFR1,FGFR3,IP6K2,SEMA4D,NOP56,ATP2C1,ERGIC3,TPPP3,FYN,ZNF274,IP6K3,SIGLEC8,GFER,GGT7,GLI2,GRB10,PRDM5,RNF165,FAM107A,UBE2QL1,MAN1B1,SYNPO,HMGCL,ZDHHC15,MSL1,TJAP1,ZNF678,FAM69A,GPR62,KCNK3,CREG2,STXBP5,L1CAM,PAXBP1,ASPRV1,MAP6,MEIS1,KCTD6,MMP17,GIT1,PTOV1,MYO7A,NNAT,CNTN3,PCDHGC3,ZDHHC8,KCTD15,PLCD1,PLIN1,SLC25A23,MTRF1L,PNMA3,POLR2F,FSD1,KANSL1,MAPK4,MASP1,PTPRE,PTPRN,TTC13,IQSEC3,UBR7,PRIMA1,PNMA8A,RPE,SNX22,ATP8B4,GLDN,RYR3,ATXN2,FNDC3A,FHOD3,WDR37,SEPHS1,SLC9A5,MAST1,MBD5,KIF13A,CABCOCO1,SNRPN,TMCC1,PDZD2,FNBP1,IZUMO4,TSPYL2,DDN,ST5,SUPT5H,SLC37A2,EXOC7,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNE1,NAT16,PHF24,SIK3,CYB561A3,C18orf54,ERCC6L2,LRRC8A,RASD2,SYNPO2,CLEC2L,MTCH1,LAT2,NPDC1,RICTOR,ZFP41,TMEM198,EML6,MEIS3,GDPD5,HPS4,SEMA3B,URM1,MARCH8,PHTF2,CASC15" MicroRNA hsa-miR-1200:mirSVR_highEffct hsa-miR-1200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.84E-66 4.95E-62 4.93E-65 4.53E-64 160 861 "SYN3,AS3MT,XKR4,PTCHD1,INTS2,MTUS1,OSBPL8,CC2D2A,ZNF687,APBA2,BCAS1,CDK13,NCOA1,SLC2A11,DOCK11,RGS9,NRP2,C5,KALRN,CAPN3,CARS,CBR1,L3MBTL4,MAGI1,CDR1,TIGD7,NDST3,PPT2,ABCG2,LETMD1,IGDCC3,CPS1,CREM,RBM39,ANKRD44,CS,CSF2RA,CST3,PHF14,ZSCAN23,DCAF4,TCAF1,ZFYVE16,CENPL,ARMCX4,PITPNC1,HEPH,EXOG,USP3,ARRDC4,DTNA,ABCC5,E2F6,WDPCP,YAF2,PHF20L1,COPS4,PLEKHA1,LRRC17,SRRM1,IGSF6,NRN1,ABCA8,TAOK3,STRADA,ZNF589,GTF2IRD2,FGFR1,ATP13A4,TMEM107,KHDRBS3,HHIPL1,AP4B1,GAA,NEU3,GCK,SULT1C4,TXNL4A,TNRC6A,CBX1,LNX1,TDRKH,PCLO,STMN2,ATP2B1-AS1,GRIA2,ZBTB49,LINGO1,FRMD5,BACH2,AGBL5,HNF4G,DHX35,HSPA1L,SLC35G1,HECTD2,NCOA7,MARK1,MIA2,POC1B,MMP16,LYRM9,P2RX7,PDPK1,DUSP26,NALCN,EPB41L4B,POLR2F,CNNM2,APTX,PTK2,TMEM260,TUG1,CEP97,RAP1GDS1,OXR1,FIGN,KCTD17,ZFHX4,CCDC82,ELP2,ZC3H14,SALL1,TRA2B,KIF21A,PPM1E,KIF16B,FBXO11,FAM81A,SLC14A1,ZNF667,ANKRD36,USP33,BDP1,GLT8D1,MYCBP2,KDM4C,ATP10B,LARP4,STAC2,ADHFE1,NECAB1,VPS13A,DNMBP,SATB2,ZEB1,DOCK9,TMEM121,AP4E1,ERCC6L2,TRO,DCBLD1,TSN,ZNF610,LAT2,XRCC4,ZNF19,TRIM9,ADAMTS9,FAM13C" MicroRNA hsa-miR-17*:mirSVR_highEffct hsa-miR-17*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-65 5.66E-62 5.63E-65 5.19E-64 174 1019 "FMNL2,CCDC85A,PTCHD1,OSBPL1A,ADGRF5,AMPD2,LRCH2,ANK2,SUGT1P4-STRA6LP-CCDC180,BCAS1,CDC14B,DYNLL1,ADAM23,KALRN,SPAG9,NFS1,ZNF501,METTL6,CCNH,CD38,LRBA,LRRFIP1,CDO1,NPIPA1,RCBTB2,SRSF11,MAP4K4,AKAP7,AKAP6,COL4A5,LETMD1,ABI3BP,AKAP12,TRIM69,CSNK1G3,SIPA1L1,CST3,APPL1,PHF14,GAPVD1,RIPOR2,ARHGAP24,KIAA0586,IST1,DAPK1,PABPC5,EXOG,CPEB2,DPYSL2,EBF1,WDPCP,TSPAN5,EDNRA,PHC2,HIPK3,RASGRP1,FRY,YAF2,GOLGA7,TENM1,VPS13B,CEP78,ZSCAN30,MED12L,FGF11,BAIAP2,MAD2L2,POLK,MEX3B,UFM1,ATP2C1,ERAP1,KIAA1841,NEU3,MSTN,TOX3,MSL3,ZNF638,CBX1,ADGRA3,GPD2,DIDO1,PLCD4,KAT7,ZHX1,SMAP1,NKD1,IL6R,IL6ST,ZNF678,SLC35G1,SYTL4,MBNL1,MEIS1,NACA,CNOT4,NRCAM,OPA1,GLIPR1L2,ENPP2,LRP12,LRRN3,PPP3CA,GRAMD1C,RELN,KLK6,CNNM2,SAMD9,CNTLN,SPDL1,PTN,PTPRO,PPP2R3C,FAM184A,RAP1GDS1,ZNF493,OXR1,RADX,REV3L,GTDC1,ZFHX4,CARF,RYR3,FAM192A,DGLUCY,ATXN7,ZFP2,CASC3,SCAF8,CPEB3,NLGN1,PPP4R3A,SLC6A8,TET1,MAPKBP1,MYO16,USP33,KDM4C,ZNF423,CLASP2,POGZ,SSPO,STAU1,RGL1,NSFL1C,KLHL7,PRRC2C,PJA1,ZFP90,ZEB1,TRIM2,TCF12,SIRT1,ITGB3BP,AP4E1,AKTIP,ERCC6L2,TRIO,TRPS1,UBE3A,PLEKHH2,RICTOR,SLC47A2,ZNF19,ZNF28,ZNF74,POLR3H,FSTL5,ANKS1B,WNK3,FZD3,CASC15,KLHDC1,GAN" MicroRNA hsa-miR-1979:mirSVR_highEffct hsa-miR-1979:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-65 5.93E-62 5.90E-65 5.43E-64 163 895 "PSMG3-AS1,BRAP,PCDH19,ALCAM,CEP126,LRCH2,PHYHD1,MADD,ZFYVE28,RASL11B,ALDH7A1,BACH1,ADGRB3,SEC11C,RGS9,DST,SLC25A14,RUNX1T1,CBLN1,LRRFIP1,MAGI1,CFL2,MS4A7,NRXN3,PLAA,AKAP6,SLC4A8,RCHY1,AHCTF1,HAPLN1,ANKRD44,RGS6,ERC2,CYBB,GSDME,USP3,DTNA,DNAJB6,DNM1L,EDNRB,SEMA3D,KMT5B,EIF1,VPS13B,SRRM1,SPEG,FCGR1A,FER,POLR1B,FGF12,FHL1,SUCO,TPK1,MEGF10,GALNT15,GALC,ZNF559,PCDH17,GLI2,RAB30,GLUL,CBX1,GPD2,TDRKH,GPR12,GRIA2,AP4S1,RNFT2,ADAMTS6,RASSF8,HAS2,AGBL5,HNMT,ZIC5,FAM69A,STXBP5,L1CAM,HECTD2,MBNL1,MEF2C,MEIS1,KCTD6,MIA2,KITLG,ZNF680,NDP,NEK1,NINJ2,NPTX1,OCRL,ZNF827,CDK18,PDE4D,GNG2,PFKFB2,NLGN3,XRN1,GPSM2,LRP12,HYDIN,VPS13C,CNTLN,MTMR10,PTPRB,PTPRD,SLC25A48,RAD51D,RASGRF2,ERI2,RFX3,RNASEL,SETD5,EXD2,CCDC102B,ZNF568,FRMPD1,HKDC1,FNDC3A,FAM214B,KANSL3,BTBD7,ATF7IP,RCOR3,SNAP25,UHRF1BP1L,KDM4C,TSPYL2,ZSCAN29,SEPT8,VPS13A,SYN1,SYP,PDLIM2,TBCEL,ATMIN,ZFP90,ZEB1,SZT2,DOCK9,AP4E1,TMPO,TP53BP2,METTL3,RUNDC3B,AMACR,TRPS1,DCBLD1,ANKRD20A2,SSBP2,ZKSCAN5,UGT8,PLEKHH2,VLDLR,WIPF1,ZNF781,ZNF138,EML6,FTSJ1,KCNAB1,JMJD1C,KLHDC1,NETO1,ZNF30" MicroRNA hsa-miR-129-3p:mirSVR_lowEffct hsa-miR-129-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-65 7.30E-62 7.25E-65 6.67E-64 179 1079 "ADD2,PWWP2A,ESYT2,ZNF578,ADGRF5,C1QTNF3,SYT13,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,CDK13,MARK4,NCOA1,RASL11B,TTLL9,CFLAR,KSR1,SCAPER,MYRF,LDLRAD4,KALRN,CLDN10,LARGE1,RCBTB2,SRSF11,CHN2,RAB28,PLAA,MAP4K4,ARHGEF6,AKAP6,AKAP5,RCHY1,FAM171B,SH2B1,AKAP12,SEC24C,OSBPL3,ERC2,DCAF4,RUBCN,HDAC9,SPOCK2,IP6K1,AIF1L,ARMCX4,MYEF2,TIAM2,RUSC2,ALKBH8,DNM1,HS3ST2,ECM2,PHC2,TMTC1,FRY,EBI3,VPS13B,MRPL37,GORAB,OLFM1,FGF13,SUCO,MEX3B,PCYOX1,C2orf88,TPK1,CAMKK2,ATP2C1,ERGIC3,CELF1,MSANTD4,TVP23A,GABRG1,B4GALNT1,LRRC37A6P,KDM2B,GPD1,CACFD1,GRIN2C,CLASRP,RNF165,TOX2,HMGCL,SHISA6,MSL1,TJAP1,IL12A,ITPKA,GPR62,STXBP5,CYP27C1,TTYH2,SYTL4,MAP4,AFF1,XRRA1,ADAM22,MSR1,ZNF862,SFR1,NEK1,CNOT4,NTRK2,TBC1D25,PDCD2,PRTG,NALCN,SEMA5B,PLXNB1,EXOSC10,POLG,PPP2R5E,RASGEF1B,PRKCB,MAPK3,PSD,QRICH1,ELOVL2,PTPRG,PTPRO,RAP1GDS1,TRIM68,GTDC1,UBR7,ZNF532,GSTCD,ROBO1,SNX22,ATAT1,ZNF568,STX1B,FAM192A,SEC14L1,KIF21A,FBXO11,R3HDM2,CNKSR2,EPN2,SLC6A8,SLC14A1,BTBD7,CXXC4,SNRPN,NMNAT2,STAU1,CEP68,PHLDB1,SEPT3,NSFL1C,VPS13A,TMEM150C,SYT1,COBL,KLHL4,CLASP1,SYNE1,USP32P1,CYB561A3,AP4E1,MTMR14,TMPO,RGMB,ELP5,NEIL2,AMACR,UBE3A,RICTOR,ZBTB38,AMZ1,MEIS3,DNALI1,STOX2,HPS4,GAL3ST3,NAV3,HNRNPA3,FBXO36" MicroRNA hsa-miR-101:PITA hsa-miR-101:PITA_TOP PITA 1.79E-65 1.00E-61 9.93E-65 9.14E-64 121 479 "ASIC1,FMNL2,ADCY6,SPOP,UNC79,AMPH,OGT,LRCH2,PPFIA4,TMEFF1,ATP2B2,KIF1A,MTMR2,JAZF1,MTMR7,CBFA2T2,C1orf52,LONRF2,MAGI1,CLCN3,SULT4A1,MYRIP,CSNK1G3,SOCS5,APPL1,KIAA0408,LONRF1,SPATA2,TIAM2,RAB39B,CPEB2,ABCC5,YAF2,KMT5B,EGR3,ELN,TMEM35A,EYA1,FGFR3,MEX3B,DOT1L,KAT7,FAM222A,HAS2,NEGR1,AGFG1,SMAP1,SOWAHA,JAK2,IPO5,STMN1,PACRG,MARK1,MBNL1,MEST,MITF,XRRA1,MYCN,NEXMIF,NACA,NOVA1,NRCAM,CLDN11,PCDH8,CDK18,PDE4D,ENPP2,GPR85,PURG,FA2H,LRRN3,PTCH1,USP47,KHDRBS2,REV3L,NUDT11,ZFHX4,ZNF532,SETD5,ROBO2,RORB,FBXW7,RYR3,SGK1,CPEB3,ABLIM3,BTBD3,CCDC88A,SLC12A2,SMARCA4,SOX11,SP2,TEX2,POGZ,ERBIN,PRRC2C,ADAMTS17,PLCB1,CAMTA1,TAL1,PDLIM2,FBXW11,TCF4,DMXL2,PUM2,FRYL,HEY1,RIMBP2,KAT6B,TRPS1,SSBP2,FLRT2,PCDH20,ZIC1,TRIM9,EMSY,MPPE1,HNRNPA3,ADAMTSL3,ADAMTS10,KLHDC1" MicroRNA hsa-miR-4293:mirSVR_lowEffct hsa-miR-4293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.89E-65 1.06E-61 1.05E-64 9.64E-64 191 1226 "RALGAPA1,SYS1,KLHL32,GALNT16,ADD1,RNF150,SLC24A4,KCTD16,KIAA1324,SRPX,FGD2,PHF12,LGR5,AQP6,SFMBT2,CASK,ARRB1,CDK13,SLC2A11,BACH1,BCS1L,ARHGEF7,SCAPER,PTBP2,VXN,CAST,CBR1,CD38,ARHGEF2,DLGAP1,SRSF11,PLEKHB1,PCYT1B,ARMC8,ANKRD35,ZNF521,ANKRD44,SNCAIP,ARHGEF10,VAC14-AS1,PHACTR3,FAM169A,APPL1,GREB1,CYBB,LIN54,AIF1L,DBN1,PITPNC1,YTHDC1,MYEF2,FBXL5,RHOBTB1,KIF19,ZNF582-AS1,E2F6,MRO,EPB41L2,CEP85L,ADGRV1,TBC1D16,FER,ATP13A4,FLT1,STAU2,HRASLS5,GABRG1,SEPT9,SRRM4,LRRC37A6P,USP19,ZNF638,LUZP2,ZNF782,LILRB4,TDRKH,FUT10,C1QL4,SPACA9,ADAMTS13,GRIN2C,GSTM5,FAM222A,MAN1B1,MYLK2,INSM1,ITGA7,KCND1,LMO2,MAP2,TM6SF1,MEIS1,AFF1,MMP16,ADAM22,RTL5,MYT1,NDP,NPTX1,NTRK2,NUCB2,LOC100128398,PCSK5,PDE1B,GNG2,SEMA5B,CCSER2,SNX10,ZFYVE21,PURG,EXOSC10,ING3,POLG,SH3KBP1,POU6F1,PRKAB2,MAPK4,GRAMD1C,MASP1,BCAS3,PIGG,MTMR10,PTPRD,SUSD4,NWD1,RBBP6,UBR7,KLHL11,CCDC82,KLHDC8A,ARMC5,CARF,RORB,RPL15,ATAT1,ZNF331,RASA3,SGK1,FAM102A,CNKSR2,SEC31A,PEX26,EPN2,FAM214B,SEPHS1,SLC12A2,ZNF667,SNAP25,MBD5,SNRPN,TMCC1,KDM4B,FAM219A,KDM3A,TSPYL2,SSTR1,SSTR2,ZC4H2,SSPO,TTBK2,SULF2,ZC3H4,PRRC2C,ARHGEF9,VPS13A,SYN2,TAL1,TPCN2,TRIM2,PCDHA5,GPR161,ZNF106,SLC44A1,NR2E1,SMUG1,AMACR,TRO,GUSBP1,ZNF24,TRIM9,MKRN3,CELF4,FSTL5,MAP3K12,HPS4,PDSS2,HNRNPA3,CASC15,KLHDC1,AP3B2,FAM198A" MicroRNA hsa-miR-493-5p:TargetScan hsa-miR-493-5p TargetScan 2.14E-65 1.20E-61 1.18E-64 1.09E-63 132 580 "ABR,FMNL2,RNF150,HECW2,OSBPL6,PITPNM2,ANK2,MAP4K3,PHF12,MADD,MARK4,NCOA1,RASL11B,ATP2A2,ADAM23,BCL7A,FUBP1,MTMR3,RUNX1T1,ENTPD6,DGKI,CDH2,LRWD1,NRXN3,AKAP6,NRG2,NSL1,AKAP12,LRIG1,PITPNM3,KIAA0408,SCRN1,BRINP1,JAKMIP2,ELMO1,GRIN3A,DMD,NR1D2,DNM1L,RASGRP1,EGFR,MBNL2,RGS17,SCML2,FOXO3,PSD2,FAM49B,CAMKK2,FUT9,MPP6,GABRG2,GAD1,CPLX2,AHDC1,GFRA2,MALT1,GLUL,KDM2B,RASSF8,HMGCR,NEGR1,AGFG1,MYLK2,METTL21A,KIF2A,L1CAM,NCOA7,LSAMP,MARK1,MEF2C,MGAT3,SCAMP5,GIT1,PDE1C,PDE4D,PDPK1,NLGN3,PIK3R1,KCTD15,PCDH18,PURG,LRP12,PPP2R2C,PPP3CA,PKIA,CNNM2,PTCH1,PTPRD,RDX,ROBO2,RPE,RXRA,SALL1,CSRNP3,ATXN2,FNIP1,GALNT10,NLGN1,ELMO2,CXXC4,LIMCH1,MBD5,KDM3A,NMNAT2,MYCBP2,RBM26,LMO3,LARP4,DIP2A,NECAB1,ANKRD28,ANKRD12,FBXW11,CLASP1,FAM189A1,PUM2,CRTC1,GPRIN3,NR2C2,OSBP2,FLRT2,REEP1,EML6,CADM2,EVI5,KCNAB1,FZD3,KAT6A,HNRNPA3,FXR1,NETO2,NETO1" MicroRNA hsa-miR-33a:mirSVR_highEffct hsa-miR-33a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.36E-65 1.32E-61 1.30E-64 1.20E-63 171 990 "ABHD6,FMNL2,BEND6,SORCS2,CC2D2A,ALCAM,UNC79,AMPH,CDC42BPA,DPP10,SEMA7A,PHF12,MAGEE2,TNRC6C,SPTBN4,ZFYVE28,ZNF583,SLC2A11,BACH1,ADGRB3,CACNA1B,THSD7A,KALRN,PTBP2,LDB2,USP6,CHN2,CLCN3,QKI,MAP4K4,IQCK,ARMC8,AKAP6,AKAP12,CS,RGS6,SEC24C,VCAN,SOCS5,SLITRK5,DZIP3,PHF14,HDAC9,KATNAL2,ZFYVE16,DGKB,MYEF2,PLPPR4,SPOCK3,WDR20,RAB39B,RCAN1,ARRDC4,DTNA,GOLT1B,E2F5,AASDH,EBF1,EDNRB,FCF1,SEMA3D,EGFR,CALCRL,VPS13B,CLVS1,ABCA8,RPS6KC1,FER,OLFM1,FGF14,SMC2,ATP6V1H,KHDRBS3,CELF1,ERAP1,LRRC37A6P,MSTN,GGTA1P,HTATSF1,GPD2,STON1,PRDM5,ZNF496,ADAMTS6,MAP4K5,RASSF8,HAS2,ZHX1,BACH2,HMGCR,HNMT,C9orf129,ZDHHC15,METTL21A,KCND2,LIG4,LSS,MARK1,MATN3,MBNL1,MEIS2,POC1B,MMP16,MSR1,MYO9A,CNOT4,NPY,NPR2,OCRL,GPR137C,PDE4D,ENPP2,PLIN1,PCDH18,PDZRN4,TRHDE,ING3,SH3KBP1,PPM1B,PPP3CA,MASP1,CNTLN,TMEM260,PTPN13,PTPRB,TTC13,ZNF615,MARCH1,RADX,ZDHHC14,RGS12,SETD5,CARF,RPE,NEK11,FBXW7,CCDC112,TRAPPC13,SCN8A,CPEB3,FAM81A,WDR47,SLC12A2,SLC14A1,SNRPN,MYCBP2,IQSEC2,ZNF302,SAMSN1,VPS13A,AGTPBP1,DMXL2,SATB2,ZEB1,TEK,ZFPM2,ITGB3BP,CSMD1,KCNE5,UGT8,TBC1D15,XRCC4,MICU3,TRIM9,LAMP5,EMSY,PRTFDC1,NAV3,WNK2,RGS7BP,FAM13C" MicroRNA hsa-miR-624*:mirSVR_highEffct hsa-miR-624*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-65 1.32E-61 1.31E-64 1.20E-63 154 802 "RALGAPA1,CLK4,CCDC85A,AXIN2,DPY19L2P4,AP2A2,ZNF608,OSBPL1A,WDR35,PCDH10,UNC79,MAP4K3,PARG,CDC14B,PPP4R4,SPTBN4,ZFYVE28,ARNTL,RIPK1,DOCK11,DDR1,CBLN1,KRIT1,DGKI,CDH2,LOC730101,MAGI1,CFL2,CHN1,COL4A5,CNRIP1,CLOCK,CRMP1,RNF14,CSNK1G3,ERC2,DCAF8,ZFYVE16,LONRF1,LIN54,ZNF582-AS1,CHRDL1,NR1D2,SLC25A18,ABCC5,DNM1L,GOLT1B,AASDH,KMT5B,EIF1,F8,SCML2,RACK1,FER,POLK,SEC23B,NBEA,SMC2,STAU2,MSANTD4,GABRA3,GAD1,GHR,GLI2,HTATSF1,PRUNE2,PCLO,KAT7,HSF2,MYLK2,SLC35G1,METTL21A,HECTD2,NCOA7,MAN2A2,MBNL1,TM6SF1,KITLG,MITF,XRRA1,MOV10,NELL2,NF1,NFE2L2,OXTR,ETFRF1,PCDH8,PCSK5,CYTL1,MTRF1L,SH3KBP1,GRAMD1C,HYDIN,DCHS2,TMEM260,PTPRB,PTPRE,RAD17,FAM184A,RAP1GDS1,OXR1,RBBP8,RDX,NUDT11,ZNF532,SETD5,CARF,ELP2,FBXW7,ZNF568,RYR3,FOXRED1,NUBPL,WDR37,FAM214B,CCDC88A,SLC12A2,MTERF2,TET1,MBD5,UHRF1BP1L,ZC3H13,TSPYL2,NXT2,RGL1,VPS13A,SYPL1,SYT1,PJA1,MCF2L,ADGRL3,SATB2,SZT2,FRYL,CCDC173,FAM200B,SIRT1,AP4E1,AKTIP,TLR4,METTL3,NEIL2,CLEC2L,USP1,WIPF1,MICU3,REEP1,SPIRE1,CADM2,PRDM10,FZD3,UBE3B,TTC7A,KLHDC1" MicroRNA hsa-miR-145*:mirSVR_highEffct hsa-miR-145*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-65 1.75E-61 1.73E-64 1.59E-63 169 969 "KCNH8,NCKAP5,XKR4,NDRG2,AXIN2,PCDH19,TXNDC16,AK2,CEP126,DPP10,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,ZBTB10,NCOA1,NUMB,N4BP2L1,ATP6V1G2,ADAM23,TTLL9,BACH1,ADGRB3,CFLAR,KALRN,CAMK2G,SLC25A14,USP6,LRBA,QKI,LETMD1,SLC4A8,RTTN,RNF14,NCOR1,CS,PUM1,RIMS2,CYBB,DOCK4,KIAA0586,PITPNC1,KLHL3,DDX46,RHOBTB1,PLPPR4,WDR20,RAB39B,USP3,ABCC5,AASDH,EBF1,FCF1,FSD1L,KMT5B,EGR3,TNK2,EIF1,COQ7,RCAN2,ENPP6,DNAJC27,CHST15,FCGR3A,PSD2,FOLH1,HRASLS5,B4GALNT1,GHDC,ERAP1,DISC1,IGSF5,GCNT2,GGTA1P,GGT7,PPARGC1A,MALT1,RAB30,GPD2,GRIA2,RNF165,PSIP1,GUCY1B1,IRAK3,TCEAL6,SMAP1,ZNF181,RBPJ,LRRTM1,KCND2,MAN2A2,KITLG,AFDN,MPP2,ZNF680,MSR1,MYO7A,MYO9A,NUCB2,OXTR,ETFRF1,GPR85,GNG2,ZNF655,RETREG1,GPSM2,PURG,EPB41L4B,PCDHB17P,PKIA,GRAMD1C,MASP1,PTPRD,TTC13,ACSS3,CCDC40,FAM184A,MSANTD2,PCMTD2,MRAP2,SNX22,BAALC,AP1AR,RMI1,SEC14L1,KIF27,FHOD3,FAM81A,SLC2A5,KANSL3,CCDC88A,BTBD7,COA1,RCOR3,MYO16,USP33,DOP1A,KDM3A,KDM4C,SPART,CLASP2,NKAIN2,TTBK2,SULF2,PRRC2C,VPS13A,COBL,CAMTA1,MCF2L,FAM208A,ZFP90,USP32P1,ARHGAP9,TK2,ERCC6L2,R3HDM1,TPM1,NEIL2,ANKRD20A2,SSBP2,VLDLR,RICTOR,MKRN3,UPF3A,FAM13C,ACTR3B,RNF170,NETO1,SOCS4,SENP7" MicroRNA hsa-miR-222*:mirSVR_highEffct hsa-miR-222*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-65 2.66E-61 2.63E-64 2.42E-63 162 893 "ACADM,HACE1,TAOK1,ALCAM,ARHGAP20,UNC79,PKP4,UPRT,NCOA1,NUMB,N4BP2L1,FUBP1,KALRN,CAST,CBLN1,LRBA,DCLK1,LOC730101,CFL2,SRSF11,MS4A7,CLCN3,MAP4K4,CNR1,ARMC8,COL4A5,LETMD1,SEC31B,PREPL,RNF14,CSF1,OSBPL3,CST3,TCAF1,CENPL,TMEM170A,GIT2,ARMCX2,ZBTB24,ECM2,KRBA2,AASDH,EBF1,EDN1,ANKRD46,FRY,STX2,CEP85L,ADGRV1,RACK1,CEP78,FCGR3A,GORAB,MED12L,TMEM164,TMEM107,FAM49B,ZNF605,MPP6,OGA,MEGF11,ERAP1,MTHFD2,NEU3,GCNT2,PCDH17,TOX3,ZNF638,GPD2,LPAR4,CNTRL,HNMT,SMAP1,MSL1,ZNF678,GPR62,KCNJ5,KIF2A,KIF5A,KTN1,L1CAM,ZNF667-AS1,MEF2C,MEIS2,SRSF12,XRRA1,ZNF680,ADAM22,MSR1,NRBP2,NEK1,NOVA1,DNHD1,SLC11A2,GPR137C,ETFRF1,GPR85,PFKFB2,FAM216A,SMIM7,ZNF426,TRHDE,PPM1B,PPP2R5E,RANBP3L,CNTLN,BDNF-AS,PTPRE,PTPRG,PTPRH,PTX3,MARCH1,ACSS3,RAP1GDS1,RASGRF1,KHDRBS2,GAL3ST4,SLC25A36,ELP2,ARMH4,ZC3H14,MCMBP,PTGR2,MEG3,ABCA11P,TRAPPC13,ATXN7,TNFRSF19,TRA2B,SH3GL3,ABLIM3,WDR47,CCDC88A,SLC12A2,SNAP25,LMBRD1,SNRPN,LMO3,NKAIN2,ELOVL4,ANKRD28,FBXW11,TRIM2,AP4E1,NACC2,SYNPO2,DCBLD1,ANKRD20A2,HIRA,ATP6V0E2,EMSY,EVI5,KCNAB1,FAM13C,AMN1,SMIM8,PHTF2,CASC15,ADAMTSL3,TIGD6,FXR1,DPF3" MicroRNA hsa-miR-492:mirSVR_lowEffct hsa-miR-492:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.85E-65 2.71E-61 2.67E-64 2.46E-63 179 1088 "EMILIN3,XKR4,ADD1,RNF150,OLMALINC,TAOK1,LRFN1,CDC42BPA,PPFIA4,SUGT1P4-STRA6LP-CCDC180,CDK10,SEMA4G,PLA2G4C,LINC00173,MARK4,NCOA1,NUMB,SLC4A4,BACH1,KSR1,ARHGEF7,RAB29,CA12,DDR1,PTBP2,VXN,RUNX1T1,ENTPD6,ZBED1,TPP1,DGCR9,SRP14-AS1,SUMF2,IGDCC3,SEC31B,CREM,ENTPD4,SH2B1,ANKRD44,SNCAIP,VCAN,CTH,INTS1,IST1,DAPK1,ELMO1,MFAP3L,C2CD2L,DDX46,SV2B,DLX1,DNAH9,DOCK2,SLC12A6,DRP2,ECM2,KRBA2,ANKRD46,EGFR,EPB41,EPHB1,IGSF6,ZNF549,MRPL10,SIRPB1,CORO2B,ZNF589,FER,GTF2IRD2,FGF11,FGFR1,BAIAP2,FHL1,HPCAL4,NOP56,ZNF605,STAU2,ZNF274,ALDH1L1,ARFIP1,SESN1,AHDC1,GGT7,AIFM3,LINC01089,MAN1B1,ARHGAP36,BACH2,EID2B,C2orf72,FAM69A,SYTL4,ASPRV1,MAN2A2,CHIC1,MEIS1,MPP2,PTOV1,N6AMT1,MYO6,RTL5,FXYD7,NNAT,VWA2,NOVA1,DNHD1,NPTX1,NUCB2,OCRL,LOC100128398,CNTN3,SLC10A4,SEMA5B,PURG,PRIMPOL,PNMA3,SEPT4,FSD1,PPP1R1A,GRAMD1C,ZSCAN32,C1orf109,ZSCAN2,NKAIN1,TTC13,MARCH1,CCDC40,GTDC1,UBR7,MRPS18A,ZFHX4,ROBO2,SGSM1,EMID1,STX1B,DGLUCY,SBF1,SCN2B,FAM102A,SHC4,FNDC3A,ST6GAL1,ANKRD6,NUBPL,PPP4R3A,BTBD3,SLC6A11,ATF7IP,SNRPN,KDM4C,NKAIN2,ZSCAN29,RHBDL3,ARHGEF9,DNAJC9,MLST8,SZT2,USP32P1,CYB561A3,R3HDM1,TPM1,SMUG1,TRO,TTTY15,GORASP1,BCL2L13,TBC1D15,CLIP2,TRIM9,LYPD6,ZNF154,SPIRE1,LAMP5,SMARCAD1,EMSY,PRDM10,PHTF2,TRAM2-AS1,SPATA13" MicroRNA hsa-miR-3138:mirSVR_highEffct hsa-miR-3138:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.52E-65 3.09E-61 3.04E-64 2.80E-63 163 905 "CCDC85A,ADGRF5,C1QTNF3,SEMA6A,PCDH10,SYT13,DPP10,PCDHGB4,ZNF583,SYNJ1,DDR1,CALM1,KALRN,CAST,CDC25B,CHN2,FAM189A2,FHL5,AKAP6,LETMD1,SLC4A8,RNF14,CSF1R,RGS6,UBXN2A,ZSCAN23,GPRASP1,ZFYVE16,TM9SF4,TMEM170A,ZBTB24,EXOG,USP3,DTNA,ABCC5,GOLT1B,YAF2,EGFR,AASS,C3orf18,PAN3,ENO2,EPB41,GPHN,SRRM1,DENND4A,SIRPB1,GMPR2,NRN1,ZNF461,DLC1,CEP78,SCARA3,NELFCD,SMC2,SPECC1,CGREF1,MEGF10,DISC1,TXNL4A,GLI2,RAB30,GLUL,DCLK2,STON1,KAT7,GUCY1B1,SHISA6,SMAP1,NME9,KIT,SYTL4,MBD1,P2RY13,NELL2,NF1,OPA1,LOC100128398,CLDN11,PCDHGC3,PDE4A,ZFYVE21,PPM1B,PPP2R2C,PPP2R5E,PPP3CA,KANSL1,MAPK10,GRAMD1C,GDPD1,DCHS2,MASP1,TMEM260,TMEM255A,RAD51D,ZNF493,RASGRF2,ERI2,RGS12,ZFHX4,ZNF532,SETD5,SNX22,ZNF354C,PPM1E,WDR37,PPP4R3A,BTBD3,ZNF430,SLC12A2,MBD5,LMO3,ATP10B,CLASP2,SS18,MPRIP,PRRC2C,NUDT10,TACR1,MTCL1,TBL1X,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ARHGAP9,CYB561A3,AP4E1,TIAM1,RIMBP2,TPM1,C9orf85,SMUG1,TRIO,AMACR,TRO,TSC1,TTTY15,HSPBP1,ZNF610,FLRT2,VLDLR,WNT7A,ZFP37,ZNF711,AGMO,FSTL5,MAP3K12,TMEM178A,KCNAB1,FZD3,RNF170,FRMD6,NETO1,LAS1L" MicroRNA hsa-miR-324-5p:mirSVR_lowEffct hsa-miR-324-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.21E-65 4.59E-61 4.52E-64 4.16E-63 177 1068 "KCNH8,ASIC1,CCDC85A,AP2A1,HACE1,ZNF578,TAOK1,SMIM17,MARCH4,PCDH10,GPRASP2,LRCH2,SFMBT2,SEMA4G,SPTBN4,CDK13,ZBTB10,ATP1B3,ALDH7A1,ADAM23,TTLL9,AZGP1,ADGRB1,LINC00847,KSR1,MTMR3,CFAP410,CA12,THSD7A,CAST,RUNX1T1,USP2,LRRFIP1,PPT2,QKI,HOMER3,IGLON5,SLC4A8,SMARCAL1,NCOR1,CRYM,SNCAIP,SEC24C,KIAA0040,ERC2,GPSM1,FAM131B,KIAA0408,ARHGAP32,ZNF337,DGKB,FBXL5,TMEM130,ALKBH8,FAM107B,GRIN3A,RPS6KL1,SLC29A4,CDON,SLC12A6,ACOT8,DTNA,SNX29,HIPK3,FCF1,C3orf18,RABEPK,VPS26C,RASL12,EZH1,ARMCX1,TMEM132C,CORO2B,ST3GAL6,STRADA,SUCO,MEX3B,SPECC1,CAMKK2,NSG1,SARAF,TMEM8B,ALDH1L1,GGT7,RAB30,HTATSF1,GNG4,ADGRA3,GPD2,CIT,ATOH8,IRAK3,HAS2,DDX19B,SYNPO,CELF5,IRF8,RBPJ,ZNF678,KHK,LINC00634,CYP27C1,KTN1,HECTD2,MAP2,PPM1L,DBNL,RTL5,ZNF862,P2RY13,NBL1,NDP,DNHD1,PCBP3,NTRK3,P2RX7,CDK18,PDE4D,GNG2,PFKFB4,NLGN3,PIK3C2A,XRN1,FAM216A,SMIM7,PDZRN4,EPB41L4B,NKAIN4,PRKAB2,DCHS2,WBP1L,PIGG,PID1,SLC25A48,RAD17,SH3TC2,ZNF493,KCTD17,NCBP3,FAM192A,DGLUCY,ATXN7,MRAS,KIF16B,HKDC1,SLA,SLC6A8,ARHGEF40,SIRT2,SLC9A5,IFT122,INAVA,MBD5,SYNE2,IQCE,TCF4,ZEB1,CLASP1,NAT16,FAM189A1,PUM2,THRA,ERCC6L2,RIMBP2,SYNPO2,AMACR,EIF4ENIF1,BCL2L13,WIPF1,AGMO,SPHK2,PRDM8,CIAPIN1,ITM2C,PARP11,EPM2A,NLRP3" MicroRNA hsa-miR-3185:mirSVR_highEffct hsa-miR-3185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-64 6.19E-61 6.08E-64 5.60E-63 195 1289 "RALGAPA1,C3orf14,BEND6,DPY19L2P4,HECW2,HFM1,ZFAT,LCORL,PHF12,TMEFF1,ARRB1,ARRB2,CADPS,RIPK1,TTLL9,ZNF599,JAZF1,CA4,KALRN,PTBP2,SPAG9,CBR1,MTMR7,LRBA,ZMYM4,LOC730101,TIGD7,CHN1,RAB33A,TPP1,CNGA3,CNR1,IQCK,COL9A1,SMARCAL1,CNRIP1,CPS1,FAM171B,SEC31B,CREM,LRIG1,CSNK1G3,PDE4DIP,CTH,RIMS2,ZSCAN23,CYBB,GPRASP1,PABPC5,ARMCX4,DGCR5,ELMO1,PLPPR4,SPOCK3,CPEB2,DPP6,DTNA,DNAJB6,GOLT1B,E2F5,WDPCP,EDNRB,PHF20L1,RASA4,KCTD3,TNK2,ENO2,EPB41L2,EPHB1,SRRM1,DENND4A,ZNF461,GTF2IRD2,FGF12,FGF14,IP6K2,AGAP2,JKAMP,NBEA,APOPT1,PDLIM5,ERGIC3,CELF1,STAU2,IP6K3,PCDH17,STARD3,GNAL,ZNF496,LINGO1,FAM107A,HSPA1L,NKD1,KIAA1755,SCIN,LAMP2,MAN2A2,MEIS2,AFDN,XRRA1,ZNF680,GIT1,MYCN,MYO7A,NEFH,NF1,NTRK2,IGSF11,OXTR,DPY19L2P2,PCSK1,PDE1C,PFKFB2,STRN3,SEPT4,EPB41L4B,PPM1B,PPP3CA,KANSL1,MAPK10,PRPSAP2,PIGG,CNTLN,STK32A,PTPRE,MARCH1,RAD51D,ZNF493,RASGRF1,KHDRBS2,MSANTD2,MORC4,RFX3,KCTD17,RIC8B,CCDC102B,MEG3,HSD11B1L,KCNIP1,RTN1,SALL1,SATB1,SCP2,CPEB3,FNDC3A,R3HDM2,CCDC92,NUBPL,SLA,FAM81A,SLC6A8,SLC11A1,RCOR3,TTC17,TRERF1,SP2,HECW1,ZC3H13,SPTAN1,LMO3,CLASP2,SST,NUDT10,FBXW11,TPCN2,PCDHGB7,USP32P1,FRYL,SIRT1,MTMR14,TMEM9,NR2E1,TMPO,R3HDM1,RUSC1,LINC00689,GUSBP1,ZBTB14,NDRG4,LYPD6,ZNF184,LAMP5,MFF,SLC38A1,PRDM10,TMEM178A,SEMA3B,NAV3,FAM47E,DOCK8,UBE3B,MSRB3,NHSL1,FXR1,FRMD6" MicroRNA hsa-miR-526b:mirSVR_highEffct hsa-miR-526b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-64 6.33E-61 6.21E-64 5.72E-63 174 1035 "KCNH8,CLK4,ABHD6,ADD2,AXIN2,BEND6,AP2A2,INTS2,MTUS1,FAM135A,PDZD4,OGT,ANK2,APOC1,RGS20,PDE8B,STK33,CCDC74A,ZBTB10,ATP6V1G2,BACH1,ADGRB3,RGS9,DST,ST3GAL5,SYNJ2,GPC2,CALB1,VXN,SPAG9,LDB2,METTL6,USP2,CD38,C1orf52,DCLK1,CHN2,QKI,ZNF521,ZFP28,RNF14,GDA,CLIP3,CS,CSF2RA,PHACTR3,UBXN2A,RUBCN,MYEF2,DDX46,ALKBH8,SGSM2,EXOG,DMD,CPEB2,ECM2,OPTN,PHF20L1,SUGP2,EPB41,EPHB1,ENPP6,EXTL2,NRN1,SCML2,DLC1,CHST15,KAT8,ZNF589,FER,GTF2IRD2,POLR1B,POLK,IP6K2,ANKFY1,SMC2,USP21,KHDRBS3,ST6GALNAC3,SARAF,OGA,ZMAT1,CHL1,GABRG2,GAD1,FAM120B,MTHFD2,ADAM28,GHR,DCLK2,LNX1,PRUNE2,TDRKH,ATE1,ZHX1,FRMD3,ARHGAP36,HNMT,IL6ST,INPP5B,KTN1,STMN1,SYTL4,HECTD2,MBD1,POC1B,NELL2,NPTX2,NTRK2,PAX6,PCSK1,PDE3A,XRN1,STRN3,EXOSC10,PILRA,PPP3CC,VPS13C,PIGG,ZIK1,PTPRE,PTPRO,RASGRF1,RDX,MRPS18A,RIC8B,PBRM1,ZFHX4,TMLHE,ROBO1,ARMH4,SPIN3,TCP11L1,ATAT1,CLIP1,SUPT20H,FNDC3A,ST6GAL1,NLGN1,ANKRD6,ABLIM3,SLC12A2,SNRPN,UHRF1BP1L,CLASP2,SS18,APOM,SYN1,TACR1,FAM208A,KIAA1107,AGTPBP1,SLC19A3,ERCC6L2,METTL3,TRIO,TTC3,UGT8,CCDC14,XPO1,ZNF19,AGMO,MKRN3,LYPD6,FSTL5,UPF3A,PRTFDC1,PRDM10,SLC17A7,EPM2A,CASC15,KLHDC1,FXR1,FAM198A" MicroRNA hsa-miR-3149:mirSVR_highEffct hsa-miR-3149:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-64 6.58E-61 6.45E-64 5.94E-63 183 1142 "DPY19L2P4,MTUS1,OSBPL8,TAOK1,C1QTNF3,ALCAM,PCDH10,FAM135A,MAP4K3,CDK13,N4BP2L1,SEC11C,SYNJ1,ARHGEF7,IL33,CACNB4,KALRN,PTBP2,USP6,CD86,DGKI,KCNAB3,MAGI1,CHN2,RAB33A,AKAP6,LETMD1,ZFP28,CNRIP1,ANKRD44,CSF1R,CSF2RA,SLITRK5,UBXN2A,ZSCAN23,ARHGAP24,DBI,ZBTB24,DMD,PDCD6IP,AASDH,HIPK3,PHF20L1,EGFR,GOLGA7,PLEKHA1,C8orf37,CALCRL,RABEPK,SRRM1,FAM198B,CEP78,FCGR3A,SLC9B2,FGFR3,IP6K2,RGPD5,PSD2,SLC37A3,AFF2,TPK1,ATP6V1H,ATP2C1,ZNF605,DISC1,MSTN,TOX3,STARD3,KIAA1958,LUZP2,GPR12,GRM8,RASSF8,HAS2,HNF4G,ZDHHC15,IRF8,ZNF546,KCND2,KCNJ5,KIF2A,PAXBP1,HECTD2,NCOA7,MARK1,LYPLAL1,AQP11,MATN2,LRP1B,MEIS1,ZNF680,ADAM22,MSR1,P2RY13,NEK1,NTRK3,OPA1,OXTR,ZNF827,GLIPR1L2,PAX6,DPY19L2P2,ETFRF1,PDE4B,GPR85,OLA1,NALCN,PIK3R1,XRN1,PLIN1,MTRF1L,LRP12,PSAT1,EPB41L4B,PPM1B,TATDN3,NKAIN4,HYDIN,PTPN13,PTPRE,ENOX1,RGS4,CCDC82,DCUN1D2,ROBO2,GLDN,MEG3,RYR3,CCDC112,SEMA6D,SCP2,FNIP1,ZFP2,MRAS,SH3BGR,ZFP30,FNDC3A,FHOD3,NLGN1,PPP4R3A,CCDC88A,BTBD7,SLC22A4,ZNF667,RCOR3,ANKRD36,MBD5,ZNF415,BDP1,SOX15,MYCBP2,RBM26,SST,SSTR2,TTBK2,SYPL1,CAMTA1,TCF4,CUX2,ZEB1,CLASP1,SYNE1,SLC35G2,SLC44A1,NR2E1,CSMD1,TPM1,RUNDC3B,TSN,ANKRD20A2,USP1,ZNF711,ZNF28,TRIM9,MKRN3,ZNF138,CELF4,FSTL5,ANKS1B,EPM2A,DNAH10,FZD3,PHTF2" MicroRNA hsa-miR-380*:mirSVR_lowEffct hsa-miR-380*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-64 7.30E-61 7.15E-64 6.58E-63 158 855 "RALGAPA1,SYN3,CLK4,SYS1,PCDH19,HACE1,TXNDC16,SPARCL1,PCDH10,BBOX1,SUGT1P4-STRA6LP-CCDC180,UPRT,PPP4R4,TMEM108,SLC4A4,ATP1B3,ADAM23,DNAJC27-AS1,SYNJ2,IL33,PTBP2,VXN,RUNX1T1,PRC1,NUMBL,MAP4K4,IGLON5,AKAP6,ZNF385A,SLC35F1,VCAN,CNTNAP2,PPP1R16B,PHF14,PUM1,DCAF4,GAPVD1,MATR3,TMEM170A,JAKMIP2,SV2B,SGSM2,NR1D2,DMTF1,DPP6,DTNA,DNAJB6,E2F5,PHF20L1,EIF5,CALCRL,VPS13B,GPHN,ADGRV1,RACK1,STRADA,KAT8,ZNF589,UBE2E3,SYNCRIP,COQ5,ATP2C1,ZNF274,DISC1,ARFIP1,LYVE1,ZNF638,LUZP2,ADGRA3,GPD2,RNFT2,HAS2,MAN1B1,HSPA1L,FAM95B1,SOWAHA,RBPJ,SCIN,KCNN2,MAN2A2,MAP4,ADAM22,MSR1,MYO7A,HNRNPM,ALDH1L2,NOVA1,DNHD1,SETD4,CHAMP1,OPA1,CNTN3,PCDH9,NALCN,PRIMPOL,ING3,EPB41L4B,DRAM2,PPP3CC,GRAMD1C,HYDIN,ANKHD1,PTPRE,USP47,FAT4,KHDRBS2,ERI2,RGS4,MRPS18A,RIC8B,ARMC5,ELP2,RPL15,LRRK2,RYR3,SALL1,TNFRSF19,SUPT20H,KIF21A,FNDC3A,DZIP1,WDR37,ABLIM3,SLC2A5,KANSL3,BTBD7,ATF7IP,GKAP1,KIF13A,TRERF1,SOX15,GLT8D1,SPTAN1,NFASC,ATP10B,POGZ,ITPRID2,LARP4,PHLDB1,STX1A,ALG1,KLHL4,SATB2,TRIM2,SLC44A1,TIAM1,BHLHB9,TRO,PPIL6,TSN,TTC3,XPO1,REEP1,AMZ1,DPYSL5,EMSY,STOX2,KAT6A" MicroRNA hsa-miR-489:mirSVR_highEffct hsa-miR-489:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-64 8.21E-61 8.03E-64 7.39E-63 163 911 "KLHL32,CCDC85A,MTUS1,KLHL13,HACE1,CC2D2A,TAOK1,SEMA6A,SYT13,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,LGR5,TMEFF1,ZSCAN18,ZBTB10,NCOA1,NUMB,ATP1B3,CA12,CALB2,KALRN,PTBP2,SPAG9,LDB2,ZMYM4,LRRFIP1,CFL2,SRSF11,CHN2,NDST3,PPT2,FBXO7,C4orf33,AKAP6,AHCTF1,ZNF521,ZFP28,OSBPL3,GREB1,KATNAL2,RIPOR2,SPOCK2,GIT2,JAKMIP2,RHOBTB1,SPOCK3,GRIN3A,NYAP1,CPEB2,DMTF1,DNM1L,KLHL5,FRY,PHF20L1,PCOLCE2,TMEM35A,PAN3,EMX2,EYA1,CLVS1,TAOK3,SLC9B2,PRKAG2,SMC2,CELF1,MEGF10,DISC1,NEU3,SULT1C4,AP4S1,ARHGAP36,HNF4G,TCEAL6,SCIN,KCNN1,KCNN2,IPO5,LAMP2,SMAD9,MAT2A,MID1,MITF,HS6ST3,MXI1,NF1,NPR2,PCBP3,NRCAM,P2RX7,PDE1C,PDE4B,PDE4D,PDE1B,GPR85,PFKFB3,NALCN,MAPKAP1,LRP12,MINDY2,PPM1B,CEP41,CNTLN,BDNF-AS,PTN,TMEM260,ACSM5,QDPR,CEP97,RAP1GDS1,RBBP6,ZDHHC14,GTDC1,FIGN,RFX3,RIC8B,CCDC82,CARF,GSTCD,LRRK2,ZNF568,SCN8A,NLGN1,ANKRD6,SLA,PPP4R3A,ARHGEF40,SLC12A4,NAPB,SMARCA4,SMARCC2,MBD5,ZSWIM8,UHRF1BP1L,MYCBP2,ITPRID2,CEP68,DIP2A,NSFL1C,PRRC2C,PLCB1,ANKRD28,SYNE1,USP32P1,ITGB3BP,ZMAT3,TMPO,TP53BP2,VSNL1,GUSBP1,XRCC4,ZFP37,ZNF711,ZNF19,ZNF28,EML6,MPPE1,EPM2A,FAM13C,CASC15,FXR1,SENP7" MicroRNA hsa-miR-1236:mirSVR_highEffct hsa-miR-1236:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-64 8.57E-61 8.38E-64 7.71E-63 194 1279 "NCKAP5,ACTN1,METAP1D,NDRG2,ADCY6,ADD2,PLEKHH1,KIAA1211,BEND6,SLC24A4,HECW2,ZNF578,CEP126,LCORL,UPRT,PPFIA3,NCOA1,ALDH7A1,ATP6V1G2,ADAM23,KSR1,DDR1,KALRN,CAMK2G,MAGI1,CDO1,CCPG1,CHN2,NDST3,CLCN3,MYL6B,CNR1,FAM149A,WHRN,COL11A2,AHCTF1,SMARCAL1,TRIM69,SIPA1L1,DCAF4,BOC,KIAA0586,ARMCX4,ELMO1,ZC3H11A,ALKBH8,RHOBTB1,RAB39B,PDCD6IP,ECM2,ABCC5,DNM1L,EDNRB,HIPK3,SEMA3D,YAF2,PHF20L1,MBNL2,TMEM35A,PAN3,EPB41L2,DENND4A,F5,TAOK3,DLC1,CHST15,ZSCAN30,STRADA,FDFT1,POLR1B,FGFR3,SUCO,ATP13A4,SLC37A3,ZNF605,CGREF1,AP4B1,HRASLS5,CHL1,ZNF234,C15orf41,GCNT2,TUBGCP4,SULT1C4,CRCP,STARD3,ZNF638,TDRKH,GRIA2,CIT,GSTM5,KAT7,RNFT2,UBE2QL1,ATXN2L,SMAP1,IRF8,MSL1,GAREM2,TJAP1,SCIN,IL6R,ZNF678,CDH20,TTYH2,LAMA2,SYTL4,PACRG,MBD1,MEIS2,ZNF92,VWA2,NTRK3,OCRL,PAX6,PCSK5,PDE4D,GNG2,NLGN3,FAM218A,JAKMIP1,PLXNB1,MAPKAP1,ING3,MINDY2,TATDN3,GRAMD1C,BCAS3,GDPD2,BDNF-AS,PTPRG,PPP2R3C,C1orf54,FAM184A,RASGRF2,RDX,GAL3ST4,ERI2,UBR7,SETD5,ROBO2,ELP2,FBXW7,ZC3H14,ATP8B4,ZFP30,SHC4,FBXO11,ST6GAL1,SYBU,ABLIM3,EPN2,NAPB,RCOR3,SNRPN,PDZRN3,BDP1,ZSWIM8,KDM4C,RBM26,NFASC,POGZ,ZC4H2,SS18,NXT2,ZSCAN29,ARHGEF9,TACR1,TCF4,SIN3B,ZEB1,NSD1,PUM2,HIF3A,RNF216P1,ZNF106,ASXL3,ERCC6L2,TPM1,ANKRD20A2,FAM155A,UBTF,PLEKHH2,CLDND1,ZNF708,TRIM9,NDRG4,UPF3A,ADAMTS9,RGS7BP,UBE3B,KAT6A,DPF3,SRGAP2B" MicroRNA hsa-miR-4315:mirSVR_lowEffct hsa-miR-4315:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.72E-64 9.61E-61 9.38E-64 8.64E-63 155 824 "KIAA1211,HFM1,TAOK1,ADGRF5,PCDH10,BEGAIN,PHF12,TNRC6C,PPFIA3,ZNF583,ADGRB3,LINC00847,NRP2,DST,BTK,WASF1,CFAP410,CAST,MS4A7,NRXN3,TMEM184B,FAM149A,COL9A1,LETMD1,COL11A2,ABI3BP,CREM,SH2B1,CRMP1,NCOR2,SNCAIP,CSF2RA,SOCS5,PDE4DIP,PNPLA8,ZSCAN23,SEC14L5,GAPVD1,HDAC4,DGKB,DBN1,DGCR5,TIAM2,SV2B,SPOCK3,DMD,RPS6KL1,DYNC1I1,CASP8AP2,PDCD6IP,RCAN1,MAMLD1,GOLT1B,MRO,PLXNC1,COPS4,LRRC17,GPHN,SRRM1,EXTL2,RPS6KC1,TBC1D16,CEP78,FCGR3A,GORAB,POLK,SUCO,SLC37A3,PDLIM5,GALC,MTHFD2,KIAA1841,ADAM28,PPARGC1A,TCERG1,COPS8,RAB30,LNX1,WDFY3-AS2,ADGRA3,PCLO,GRIA2,HNMT,IL12A,INSM1,LRRTM1,MEIS2,AFDN,LAYN,NEFM,NEK1,CNOT4,NOVA2,SMIM11A,NTRK2,NUCB2,PCSK5,GPR85,FAM218A,LRRN3,PRKACB,MAPK10,PRPSAP2,WDR25,TTC13,CEP97,OXR1,FIGN,ZFHX4,TRAPPC13,FAM192A,SALL1,SCN8A,SGK1,FHOD3,CNKSR2,WDR37,CPEB4,COA1,RCOR3,KDM4B,PDZD2,BDP1,VPS13A,NUDT10,MCF2L,TAF9,TRIM2,SYNE1,PHF24,FRYL,PMS2CL,SLC44A1,RIMBP2,PARD3,STXBP4,DCBLD1,TSC1,UGT8,ZNF709,VLDLR,WRN,XPO1,PCDH20,ZFP37,KCNT2,ATP6V0E2,CELF4,DPYSL5,EMSY,STOX2,TMEM178A,FAM13C,TMEM63C,FXR1" MicroRNA hsa-miR-518c*:mirSVR_highEffct hsa-miR-518c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.77E-64 9.89E-61 9.65E-64 8.88E-63 184 1157 "KDM5D,ADRB2,PCDH19,ALCAM,SYT13,AMPD2,PHF12,KCNAB2,UPRT,MARCH3,TMEM108,STX16,ATP2A2,TTLL9,BACH1,NRP2,KSR1,ST3GAL5,ARHGEF7,CASTOR3,GYG2,CA8,CACNB4,CBR1,CCNH,USP2,SOCS6,TPP1,SLC4A8,ZNF521,IGDCC3,C2CD2,GDA,CLIP3,CS,SEC24C,ARHGEF10,PHF14,CTH,PUM1,TCAF1,GIT2,ARMCX2,YTHDC1,DDX46,CHRDL1,GRIN3A,DPH1,DNAJB6,ABCC5,EDN1,EDNRB,HIPK3,CNNM1,OPTN,YAF2,PHF20L1,KMT5B,PLEKHA1,TNK2,RGS17,PAN3,EPHB1,STX2,MRPL37,FCGR1A,STRADA,GORAB,MED12L,ANKFY1,NELFCD,JKAMP,GAD1,DISC1,MSTN,GHR,TCERG1,COPS8,GPR12,ARHGAP36,AGBL5,NEGR1,CELF5,SMAP1,IDH3A,SOWAHA,SCIN,INPP5B,NME9,PIK3AP1,MAN2A2,MBD1,SRSF12,MEST,MMP16,MYCN,NF1,DNHD1,SLC11A2,CLDN11,PCDH9,PDE3A,SERPINI1,SMIM7,PURG,PRIMPOL,ING3,SEPT4,SH3KBP1,RANBP3L,PKIA,HYDIN,SNRK,WDR25,SPDL1,C1orf109,ZNF615,RASGRF2,RDX,DPF2,GTDC1,FIGN,RGS12,SETD5,ELP2,PCMTD2,BAALC,SPIN3,ATP8B4,ATAT1,ZNF568,CSRNP3,MRAS,SH3BGR,FERMT1,NUBPL,DHX30,FAM214B,CXXC4,LIMCH1,LMBRD1,SNRPN,BDP1,ZSWIM8,KDM4C,TEX2,RBM26,POGZ,SS18,ERBIN,STAU1,CEP68,JMJD6,PLCB1,TAF9,TBCEL,ZEB1,RPGRIP1L,TCF12,SYNE1,NAT16,FRYL,CHST8,ITGB3BP,GPR161,SLC44A1,TK2,NPL,TPM2,ELP5,RUNDC3B,UGT8,PLEKHH2,WIPF1,RICTOR,CFAP298,TRIM9,ZNF195,SLC30A4,CADM2,PPP1R3F,PLSCR4,CASC15,DPF3" MicroRNA hsa-miR-146b-3p:mirSVR_lowEffct hsa-miR-146b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-64 1.01E-60 9.79E-64 9.02E-63 207 1446 "ACHE,GALNT13,ADD2,KIAA1211,TXNDC16,ZNF687,FAM131A,CDK10,SPTBN4,PLA2G4C,NCOA1,CHID1,ADAM15,BACH1,BARD1,RGS9,NRP2,SYNJ1,SYNJ2,CASTOR3,GYG2,SGCE,PTBP2,SPAG9,LDB2,USP2,MTMR7,P2RX6,AP4M1,LRRFIP1,CHN2,MS4A7,TAOK2,EPS15L1,ARHGEF6,AKAP7,ANKRD35,CRMP1,NCOR2,ARHGEF10,CSNK1E,CSNK1G3,RIMS4,CNTNAP2,PLXNA4,UBXN2A,PPP6R2,FAM131B,CCDC144A,GAPVD1,DCAF8,EARS2,DBN1,ELMSAN1,DGCR5,LYPD1,GUCD1,POM121,RHOBTB1,PARD6A,GRIN3A,DOCK2,TOM1,MAMLD1,ABCC5,SEMA3D,EGFR,PLEKHA1,ELN,VPS13B,COQ7,DENND4A,ADGRV1,F5,RACK1,PPP1R1B,FGF14,ANKFY1,TRIM16,ZNF605,ERGIC3,ABLIM2,ZNF559,TUBGCP4,GFER,KCNMB4,WDFY3-AS2,GPD1,GPD2,PRUNE2,DIDO1,SPACA9,GRM8,CLASRP,GSTM5,BVES,LINGO1,NXPH3,ATXN2L,TNFAIP8L3,MIER3,ELOVL5,HMGCR,IGFBPL1,ZNF491,ZDHHC15,CPT1C,DHX35,CELF5,ITGA7,SLC35G1,GPR62,KCNK3,KCNN2,STXBP5,TTYH2,ZFYVE27,MAP4,MBP,MEIS1,SRSF12,XRRA1,ADAM22,MSR1,MYO6,SFR1,NEK1,VWA2,PFKFB2,PFKFB4,ZNF655,PKD1,MTRF1L,PLXNB1,PNMA3,SCHIP1,RETREG2,GRAMD1C,CNNM2,WBP1L,DEF8,PTH1R,PTPRD,FAM66C,ZNF493,RGS12,MRPS18A,TMLHE,EPHA10,RPL15,LRRK2,MEG3,HSD11B1L,FAM192A,DGLUCY,GALNT10,SUPT20H,FHOD3,SLC6A11,RADIL,NAPB,CXXC4,ABTB1,OGDHL,ANKRD36,KIF13A,FAM126B,RBM34,KDM4C,NFASC,ERBIN,ST5,RGL1,DIP2A,PRRC2C,VPS13A,MLST8,SMG6,MGRN1,ATMIN,SATB2,TNS2,THRA,WBP2,ELP5,TRIO,SSBP2,LAT2,ZNF708,ZNF19,CELF4,AMZ1,EML6,MEIS3,EMSY,DNALI1,LINC02210,TUBA1A,NAV3,PPP1R3F,FIP1L1,TRIM16L,PARP11,UBE3B,RSPRY1,MSRB3,SOCS4" MicroRNA hsa-miR-508-3p:mirSVR_highEffct hsa-miR-508-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-64 1.17E-60 1.14E-63 1.05E-62 162 902 "FMNL2,WDR35,OSBPL8,ALCAM,ABCD2,PCDH10,FAM135A,PHF12,UPRT,CDC14B,ZFYVE28,NUMB,SLC2A11,SYNJ1,MTMR2,ZNF501,LRBA,SEPT7,CFL2,NDST3,FBXO7,CNN3,SLC4A8,MAGED1,ABI3BP,RTTN,GDA,PDE4DIP,PUM1,ZFYVE16,LIN54,TMEM170A,GIT2,JAKMIP2,MYEF2,KIAA0753,CDON,ACOT8,EDIL3,SEMA3D,PCOLCE2,COQ7,NCALD,ETV1,PIPOX,NRN1,F8,DLC1,FCGR1A,POLK,HVCN1,SULT1C4,MSTN,ADAM28,GGTA1P,DBF4,MSL3,FERMT2,GPR37,GRIA2,SERP2,GRM8,RNF165,GSTT2,ZHX1,ZDHHC15,LRRTM1,STXBP5,MARK1,MAT2A,MBNL1,SRSF12,MITF,ZNF680,NRBP2,NEK1,NF1,NFE2L2,NOVA1,NUCB2,OXTR,CNTN3,GPR173,PURG,TRHDE,MAPKAP1,LRP12,SCHIP1,EPB41L4B,MINDY2,MASP1,CNTLN,PTPRD,EML5,PPP2R3C,TMEM255A,USP47,OXR1,RASGRF1,RBBP6,RGS12,SLC25A36,PBRM1,KLHDC8A,CARF,RORB,ELP2,CCDC102B,ARMH4,PTGR2,ATAT1,CLIP1,ZNF568,SAFB,SATB1,SCN8A,ZFP2,SGK1,CPEB3,CHD9,NUBPL,ABLIM3,PPP4R3A,ATF7IP,ZFP1,ANKRD36,LIMCH1,SNRPN,UHRF1BP1L,LMO3,SSTR1,TTBK2,SYPL1,ADGRL3,SATB2,ZEB1,TRIM2,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,SLC44A1,KAT6B,TTC3,PLEKHH2,KCNT2,TRIM9,FTSJ1,LAMP5,RNF103,CIAPIN1,NELFE,PHTF2,NETO1,SENP7" MicroRNA hsa-miR-34c-3p:mirSVR_highEffct hsa-miR-34c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-64 1.18E-60 1.14E-63 1.05E-62 156 836 "KCNH8,PWWP2A,MTUS1,KCTD16,RTL9,TAOK1,ABCD2,MARCH4,OGT,PHF12,APC,RGS20,ADAM23,DST,SYNJ1,CACNA1G,CALB1,ISPD,RUNX1T1,KRIT1,CCPG1,CFL2,ARMC8,AKAP6,SLC35F1,FAM171B,RNF14,TRIM69,SNCAIP,USP6NL,CCDC144A,CYBB,DOCK4,GAPVD1,LIN54,DGKB,MYEF2,ALKBH8,RHOBTB1,EXOG,CPEB2,DMTF1,DPP6,RCAN1,HIPK3,RASGRP1,OPTN,PHF20L1,MBNL2,TENM1,PLEKHA1,RCAN2,ADGRV1,ABCA8,ZNF585B,DLC1,FER,FGF14,FHL1,SUCO,MEX3B,FLT1,PSD2,PDLIM5,FAM49B,ATP6V1H,ERGIC3,CELF1,GABBR1,GAD1,MTHFD2,TUBGCP4,ARFIP1,WASHC2A,PCDH17,BRD8,COPS8,MAP4K5,HAS2,ZHX1,FRMD3,MIER3,HMGCL,DHX35,MSL1,KIF2A,LAMP2,MAP2,MARK1,AFDN,DNHD1,LOC100128398,GPR137C,PDE4D,OLA1,PLCL1,TRHDE,STRN3,SCHIP1,SDK2,KANSL1,PRKACB,EPDR1,CNTLN,ELOVL2,ZNF615,RBBP8,RNASEL,SETD5,EXD2,ROBO1,RPE,ARMH4,ADAL,PEAR1,MRAS,SUPT20H,PUF60,CHD9,FNDC3A,ANKRD6,FAM81A,PREX2,SLC8A1,CCDC88A,KBTBD4,BTBD7,RCOR3,SNCA,MBD5,FAM126B,MYCBP2,ZC3H13,ARHGEF9,SYPL1,SYT1,FAM208A,ADGRL3,PCDHB3,FRYL,SIRT1,AKTIP,PIK3R5,NPL,TRIO,TTC3,CLHC1,UBE3A,ZNF711,ZNF189,LAMP5,UPF3A,ADAMTS9,PDSS2,KAT6A,IFT88" MicroRNA hsa-miR-369-3p:PITA hsa-miR-369-3p:PITA_TOP PITA 2.32E-64 1.30E-60 1.26E-63 1.16E-62 128 553 "RALGAPA1,USP31,PWWP2A,AP2A1,PCDH19,ARHGAP20,FAM135A,LRCH2,LCORL,BCAS1,CASK,ZBTB10,EIF4G3,SYNJ1,ARHGEF7,CDH2,NOG,NUMBL,CFL2,CHN2,CNOT8,FAM19A5,MAP4K4,BAG4,ZNF521,SLC35F1,PHACTR3,ZFYVE16,KCTD8,GIT2,KLHL3,DMD,RCAN1,HIPK3,SEMA3D,YAF2,MBNL2,TENM1,EPB41,ETV1,EYA1,ACSL4,MEX3B,PDLIM5,FYN,MEGF10,CHL1,GABRB3,GFRA2,SPIN1,TNRC6A,STON1,FAM19A2,ZBTB49,ADAMTS6,BACH2,ELOVL5,NKD1,RBPJ,KTN1,MAP2,MBNL1,CHIC1,LRP1B,MEIS1,MGAT3,AFF1,MYO5A,NEFM,NF1,NPTX1,NRCAM,OPA1,CNTN3,PDE4B,PDE4D,GPR85,PIK3R1,MINDY2,PPP2R2C,PRKAB2,CEP41,PKIA,SNRK,PTCH1,OXR1,KHDRBS2,ZFHX4,SPIN3,NCBP3,SATB1,FNIP1,CPEB3,WDR47,SNAP25,MYO16,ZNF423,CDK19,RBM26,SSTR1,NKAIN2,PRRC2C,ANKRD28,FBXW11,ATMIN,TCF4,ZEB1,TRIM2,RPGRIP1L,TCF12,PCDHGA11,DICER1,ZFPM2,SLC44A1,TRPS1,VSNL1,ZNF711,ZBTB38,REEP1,ZFAND5,RNF103,NAV3,RGS7BP,HNRNPA3,PHTF2,JMJD1C,RNF146,ST8SIA2" MicroRNA hsa-miR-519e:mirSVR_lowEffct hsa-miR-519e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-64 1.42E-60 1.38E-63 1.27E-62 196 1308 "EMILIN3,SYS1,GALNT13,ADD2,PTCHD1,SYT13,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,VAT1L,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,ATP2A2,LINC00847,BID,SYNJ2,RAB29,CACNB4,SLC25A14,VXN,SPAG9,CERS5,ARHGEF1,SCARB1,CD38,SEPT7,MAGI1,ASIC3,CHN2,FBXO7,QKI,SRP14-AS1,WHRN,SLC35F1,SEC31B,GDA,RGS6,GALNT9,CTH,ZFYVE16,MAML1,IST1,GIT2,YTHDC1,ZNF804A,SV2B,DMD,DMTF1,DPH1,EDN1,ANKRD46,CNNM1,FAM13A,PLXNC1,CERCAM,EMX2,VPS26C,GMPR2,HSPA12B,FAM198B,ZNF585B,FCGRT,ZSCAN30,FGF1,FGF11,PCYOX1,SLC37A3,AP4B1,GABRB3,ERAP1,LRRC37A6P,GATM,TUBA8,MSTN,TOX3,RAB40B,STON1,SERP2,GUCY1B1,SLC2A6,IDH3A,IL6ST,KIF5A,KIT,KTN1,STMN1,GPR155,CLEC18A,LRP1B,MEIS2,SAMD5,ADAM22,MSR1,NRBP2,MYO5A,HNRNPM,ZC3H12B,DNHD1,SLC11A2,P2RX7,GPR137C,PDE1B,PFKFB4,OLA1,DUSP26,XRN1,NLE1,PLCB2,SLC25A23,PCDH18,SCHIP1,FSD1,PPP2R5E,HYDIN,MTMR10,ELOVL2,PTPRE,TMEM255A,FAM184A,ZNF493,GTDC1,SLC25A36,LGI2,C12orf49,ALG9,ARMC5,CCDC25,ATP8B4,TCP11L1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,TRAPPC13,SEMA6D,ATXN2,ATXN7,PEAR1,CASC3,MRAS,SUPT20H,SH3GL3,ASAP3,SHMT2,CHD9,ELMO2,CPEB4,SMARCD3,MYH15,RCOR3,KIF13A,SNRPN,USP33,NMNAT2,NEK4,SULF2,SLC37A2,C12orf76,SIN3B,TRIM2,PHF24,FRYL,DICER1,SIRT1,ZFPM2,GALNT17,LRRC8A,TP53BP2,STXBP4,PPIL6,SGK3,RPL7L1,UCHL1,UGT8,CCDC14,TBC1D15,GUSBP1,XPO1,ZNF711,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,NAV3,EPM2A,RGS7BP,DOCK8,RTN4,TRAM2-AS1,RNF170,DPF3,SENP7" MicroRNA hsa-miR-203a-3p.1:TargetScan hsa-miR-203a-3p.1 TargetScan 2.68E-64 1.50E-60 1.46E-63 1.34E-62 140 670 "NDRG3,FMNL2,BRAP,KIAA1211,KCTD16,OSBPL1A,OSBPL8,AMPD3,MAP4K3,PHF12,APC,FAM131A,CASK,ARNTL,CDK13,MARCH3,INSYN2B,BCL7A,LDHD,BMPR1B,DST,CALM1,PTBP2,RUNX1T1,CFL2,PLAA,CLCN3,C4orf33,HECTD1,MAP4K4,HOMER3,CNTFR,RTTN,NRG2,CLOCK,RBM39,HAPLN1,RIMS4,PLXNA4,APPL1,PLCXD3,HDAC9,MATR3,DGKB,MYEF2,FBXL5,CHRDL1,NR1D2,DNM1L,EBF1,EDN1,EDNRA,HEYL,MBNL2,EGR3,RGS17,EPB41,NCALD,ETV1,MRVI1,NBEA,NSG1,MSANTD4,FYN,MEGF11,GALNT15,PCDH17,GHR,RAB30,GPR75,GNG4,NXPH3,NEGR1,MSL1,NKD1,LRRCC1,KCNB1,KCNN3,KCNQ3,KIF2A,GPR155,MAPT,MBNL1,CHIC1,MEIS1,MEIS2,MGAT3,AFF1,MXI1,MYO5A,NFYA,NOVA1,OPA1,PDE4D,GPR85,RANBP3L,PRKCB,MAPK10,GRAMD1C,CNNM2,PTCH1,EML5,PTPRN,REV3L,GTDC1,FIGN,KLHL11,ROBO1,ROBO2,SALL1,FNIP1,CHD9,BTBD3,DHX30,CCDC88A,BTBD7,CPEB4,MBD5,FAM126B,NMNAT2,CLSTN2,NECAB1,ADAMTS17,CAMTA1,KIAA0930,RPGRIP1L,DOCK9,PUM2,DICER1,ITGB3BP,CBX5,KAT6B,RPRM,FAM155A,CADM2,PRDM10,NAV3,KAT6A,NETO2,GAN" MicroRNA hsa-miR-520a-5p:mirSVR_highEffct hsa-miR-520a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.20E-64 1.79E-60 1.73E-63 1.60E-62 174 1042 "BRAP,FZD9,CC2D2A,NT5C3B,CDK13,NUMB,RASL11B,SLC4A4,ZNF582,N4BP2L1,TTLL9,ADGRB3,KSR1,ZNF555,KALRN,SCARB1,SEPT7,CFL2,CHN2,CLTB,QKI,SULT4A1,COL9A1,ABI3BP,FAM171B,RNF14,ANKRD44,CSNK1G3,PLXNA4,ERC2,ARHGEF4,DOCK4,RIPOR2,DCAF8,DAPK1,ARMCX4,KIAA0753,GSDME,DDX46,SNAP91,TMCC2,DPP6,DRP2,ECM2,ABCC5,SNX29,RASGRP1,EGFR,KMT5B,ELN,TUBD1,EPB41L2,TLR7,ST3GAL6,FCGR3A,FER,PCYOX1,SLC37A3,ATP6V1H,ZNF605,CELF1,GALC,IQGAP2,INPP5K,TUBGCP4,SESN1,GFRA2,GRIA2,PLCD4,GRM8,COQ10A,IRAK3,VSIG4,HMGCL,AGBL5,SHISA6,IDH3B,IGF1,ITPKB,KCNB1,CREG2,KIF2A,IPO5,PAXBP1,SMAD1,MEIS1,MEIS2,MID1,POC1B,MN1,NDP,NOVA1,NUCB2,PFKFB2,RETREG1,XRN1,GPSM2,ZNF426,MTRF1L,MAPKAP1,TATDN3,PPP2R5E,RANBP3L,PRKCB,SLC26A11,GRAMD1C,DIRAS2,ANKHD1,MTMR10,TMEM260,PTPRB,ZSCAN2,MARCH1,TMEM255A,SUSD4,ENOX1,PRRT2,FIGN,UBR7,RGS4,RIC8B,RNASEL,TMLHE,ARMC5,CARF,NEK11,ARMH4,RTN1,SEMA6D,ATXN2,ATXN7,SGK1,SH3GL3,FBXO11,PPP4R3A,SLC22A4,RCOR3,DOP1A,KDM3A,UHRF1BP1L,KDM4C,RBM26,NKAIN2,ZSCAN29,CEP68,DIP2A,SYNE2,CAMTA1,FAM208A,FBXW11,KLHL4,ATMIN,SATB2,RPGRIP1L,SYNE1,NAT16,PUM2,AP4E1,TMPO,ZNF346,TRO,CCDC14,ZNF24,ZNF32,TCEAL7,CADM2,VPS35L,PPP1R3F,PLSCR4,PDSS2,UBE3B,FBXO36,NHSL1,ZDHHC20" MicroRNA hsa-miR-600:mirSVR_highEffct hsa-miR-600:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.36E-64 1.88E-60 1.82E-63 1.68E-62 166 950 "SYS1,BEND6,KLHL13,AK2,ALCAM,SYT13,LCORL,MAP4K3,RASL11B,ADAM23,DST,SYNJ1,PTBP2,CCK,AP4M1,MAGI1,CDO1,CCPG1,SRSF11,EPS15L1,PPT2,SLC4A8,HAPLN1,ANKRD44,SNCAIP,RGS6,CSNK1G3,SLITRK5,DZIP3,RIPOR2,ARMCX4,ZNF804A,MYEF2,SV2B,DTNA,ECM2,EDN1,FRY,PHF20L1,KMT5B,KCTD3,MRNIP,EPB41,SRRM1,RRAGB,ABCA8,RPS6KC1,DLC1,CEP78,C2orf88,NBEA,ATP6V1H,ERGIC3,ST6GALNAC3,GAD1,C15orf41,DISC1,SULT1C4,ARFIP1,SPIN1,ZNF638,GNAO1,FERMT2,ADGRA3,GRIA2,PRDM5,COQ10A,PSIP1,GUCY1B1,RASSF8,TOX2,ZHX1,RBPJ,ITPKB,KCND2,STMN1,PAXBP1,NCOA7,MAP2,MAT2A,MBD1,BEX5,NF1,NOVA1,PCDH8,PCSK1,PDE4A,RETREG1,PLCB2,SDK2,ING3,PPP2R5E,PPP3CA,CEP41,HYDIN,DIRAS2,KLK6,PTPRD,PEX2,CEP97,KLHDC8A,CARF,ROBO2,PCMTD2,ATP8B4,CSRNP3,ATXN7,SGK1,FAM81A,CCDC88A,RCOR3,ZSWIM8,GLT8D1,ZC3H13,CLASP2,ITPRID2,ERBIN,ST5,NEK4,DIP2A,SEPT3,SYNE2,SYPL1,KLHL4,TCF4,KIAA0930,TRIM2,TCF12,USP22,SZT2,SYNE1,PCDHB9,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,VWCE,ARL10,TMPO,BEX4,TNS1,METTL3,SGK3,FAM155A,UBE3A,UCHL1,WRN,RICTOR,ZIC1,LYPD6,ANKS1B,FTSJ1,EMSY,STOX2,MPPE1,AMN1,FZD3,KAT6A,SMIM8,PHTF2,CPNE4,LAS1L" MicroRNA hsa-miR-29a:PITA hsa-miR-29a:PITA_TOP PITA 3.39E-64 1.89E-60 1.83E-63 1.68E-62 131 583 "ASIC1,XKR4,OSBPL6,PITPNM2,USP37,SHROOM2,TMEFF1,ZBTB10,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,CPS1,CRMP1,NCOR2,OSBPL3,ARHGEF4,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DRP2,ARRDC4,FEM1B,KMT5B,PLEKHA1,ELN,MED12L,MEX3B,FOXO3,PSD2,AFF2,SESN1,PCDH17,PPARGC1A,RAB30,FERMT2,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,ZIC5,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,PRKAB2,WBP1L,SNRK,EML5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,TPM1,ZNF346,TUBB2A,UBTF,SLC30A3,EMSY,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-29c:PITA hsa-miR-29c:PITA_TOP PITA 3.39E-64 1.89E-60 1.83E-63 1.68E-62 131 583 "ASIC1,XKR4,OSBPL6,PITPNM2,USP37,SHROOM2,TMEFF1,ZBTB10,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,CPS1,CRMP1,NCOR2,OSBPL3,ARHGEF4,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DRP2,ARRDC4,FEM1B,KMT5B,PLEKHA1,ELN,MED12L,MEX3B,FOXO3,PSD2,AFF2,SESN1,PCDH17,PPARGC1A,RAB30,FERMT2,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,ZIC5,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,PRKAB2,WBP1L,SNRK,EML5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,TPM1,ZNF346,TUBB2A,UBTF,SLC30A3,EMSY,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-29b:PITA hsa-miR-29b:PITA_TOP PITA 3.39E-64 1.89E-60 1.83E-63 1.68E-62 131 583 "ASIC1,XKR4,OSBPL6,PITPNM2,USP37,SHROOM2,TMEFF1,ZBTB10,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,CPS1,CRMP1,NCOR2,OSBPL3,ARHGEF4,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DRP2,ARRDC4,FEM1B,KMT5B,PLEKHA1,ELN,MED12L,MEX3B,FOXO3,PSD2,AFF2,SESN1,PCDH17,PPARGC1A,RAB30,FERMT2,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,ZIC5,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,PRKAB2,WBP1L,SNRK,EML5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,TPM1,ZNF346,TUBB2A,UBTF,SLC30A3,EMSY,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-612:mirSVR_highEffct hsa-miR-612:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-64 1.94E-60 1.87E-63 1.72E-62 170 996 "ADCY6,ADORA2A,FAHD2CP,FAM135A,SUGT1P4-STRA6LP-CCDC180,VAT1L,ARNTL,STK33,CCDC74A,CCAR2,ATP2B2,CFLAR,PTBP2,CAST,CBS,CLDN10,METTL6,P2RX6,CD86,CD38,ZMYM4,MAGI1,TIGD7,RAB28,MAP4K4,COL4A5,GDA,TRIM69,CSNK1G3,SOCS5,VAC14-AS1,DZIP3,PPP1R16B,CTH,RUBCN,CCDC144A,TCAF1,ARHGAP24,ARMCX4,HEPH,ZC3H11A,DDX46,SV2B,CPEB2,DPYSL2,SNX29,KLHL5,FAM13A,EGR3,CERCAM,SRRM1,ZNF549,FAM198B,STRADA,KAT8,SLC9B2,FGF1,SPSB4,BAIAP2,NOP56,TMEM175,TRIM16,STAU2,MSANTD4,AP4B1,GABRA3,B4GALNT1,ZNF274,NEU3,GCNT2,COPS8,SPIN1,KDM2B,MAP7D2,POLL,GRIN2D,GSTM5,MIER3,VSIG4,IL6ST,KCNB1,GPR62,KHK,KIF5A,PAXBP1,NCOA7,LSS,PIK3AP1,MBNL1,ADAM11,MEF2C,MEIS1,KCTD6,MMP16,MYO7A,NEFH,NEK1,NFE2L2,VWA2,NTRK2,NTRK3,IGSF11,OCRL,OGG1,CLDN11,TREM2,PKM,PURG,SEPT4,POLG,SH3KBP1,PPP1R1A,TATDN3,PCDHB17P,PPP2R2B,ZSCAN32,EML5,PPP2R3C,MARCH1,RET,RGS4,RGS12,ROBO1,ELP2,MRAP2,ATAT1,CLIP1,ZNF568,RMI1,DGLUCY,SALL1,ATXN7,TNFRSF19,SEC14L1,TRA2B,HKDC1,CHD9,R3HDM2,CCDC92,ANKRD6,ATF7IP,SNCA,CMTR2,SNRPN,PDZD2,SPTAN1,LMO3,SS18,ZSCAN29,NSFL1C,COBL,MCF2L,SATB2,TCF12,ARHGAP9,PMS2CL,ITGB3BP,WIPF1,P2RY12,ZBTB14,MICU3,TRIM9,NDRG4,REEP1,SMARCAD1,EMSY,TRIM16L,UBE3B,HNRNPA3,FRMD6" MicroRNA hsa-miR-525-5p:mirSVR_highEffct hsa-miR-525-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-64 1.94E-60 1.87E-63 1.72E-62 170 996 "XKR4,BRAP,FZD9,CC2D2A,NT5C3B,PPP4R4,RGS20,CDK13,NUMB,RASL11B,SLC4A4,N4BP2L1,ADGRB3,KSR1,KALRN,CBFA2T2,SEPT7,CFL2,CHN2,CLTB,QKI,SULT4A1,COL9A1,ABI3BP,SMARCAL1,FAM171B,ANKRD44,CSNK1G3,PLXNA4,ERC2,ARHGEF4,DOCK4,RIPOR2,DCAF8,DAPK1,ARMCX4,KIAA0753,GSDME,DDX46,SNAP91,SPOCK3,TMCC2,DPP6,DRP2,ECM2,ABCC5,SNX29,RASGRP1,EGFR,KMT5B,ELN,TUBD1,EPB41L2,TLR7,ST3GAL6,CEP78,FCGR3A,FER,PCYOX1,ATP6V1H,ZNF605,CELF1,SARAF,AP4B1,GALC,IQGAP2,INPP5K,TUBGCP4,SESN1,GFRA2,GRIA2,PLCD4,COQ10A,IRAK3,VSIG4,HMGCL,AGBL5,SHISA6,IDH3B,IGF1,ITPKB,KCNB1,CREG2,KIF2A,IPO5,PAXBP1,SMAD1,MEIS1,MEIS2,MID1,POC1B,MN1,NDP,NOVA1,NUCB2,PFKFB2,RETREG1,XRN1,GPSM2,ZNF426,MAPKAP1,PPP2R5E,RANBP3L,SLC26A11,GRAMD1C,DIRAS2,ANKHD1,MTMR10,PTK2,TMEM260,PTPRB,EML5,SUSD4,ENOX1,PRRT2,FIGN,UBR7,RGS4,RIC8B,TMLHE,ARMC5,CARF,NEK11,RTN1,SEMA6D,ATXN2,ATXN7,SGK1,SH3GL3,FBXO11,PPP4R3A,SLC22A4,ANKRD36,DOP1A,KDM3A,UHRF1BP1L,KDM4C,RBM26,NKAIN2,ZSCAN29,CEP68,PRRC2C,SYNE2,VPS13A,FAM208A,FBXW11,KLHL4,ATMIN,SATB2,RPGRIP1L,SYNE1,NAT16,PUM2,AP4E1,TMPO,ZNF346,TRO,CCDC14,XPO1,ZNF24,ZNF32,TCEAL7,CADM2,VPS35L,PPP1R3F,PLSCR4,PDSS2,UBE3B,NHSL1,ZDHHC20" MicroRNA hsa-miR-302e:mirSVR_highEffct hsa-miR-302e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.52E-64 1.97E-60 1.89E-63 1.74E-62 177 1078 "KIAA1211,PTCHD1,MTUS1,AK2,SPOP,ALCAM,ANK2,PHF12,STK33,STX16,DPY19L3,BACH1,CFLAR,ST3GAL5,MTMR3,JAZF1,CA12,CALB2,MAGI1,CFL2,CHN2,TAOK2,ABCG2,C4orf33,AKAP5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,ARHGEF10,SOCS5,CYBB,BOC,DGKG,ZNF804A,MYEF2,ZC3H11A,HS3ST2,DMTF1,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,PLEKHA1,C3orf18,DCTN4,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,MSANTD4,IGSF5,TUBGCP4,GGTA1P,COPS8,TNRC6A,GLUL,MAP7D2,GPR12,GPR34,PCLO,MSL1,IDH3B,KCNN2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,PPM1L,POC1B,MYCN,MYO9A,NACA,NELL2,NF1,NRCAM,OCRL,OGG1,PCDH9,PDCD2,ZDHHC8,PLCL1,JAKMIP1,PRIMPOL,TRHDE,ING3,DRAM2,PRKACB,GRAMD1C,MASP1,SNRK,TMEM260,PTPRD,PTPRO,CEP97,FAT4,ENOX1,OXR1,RDX,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,MCMBP,RPS20,SHC4,FBXO11,FNDC3A,WDR37,PPP4R3A,ARHGEF40,SLC14A1,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,RBM34,ZC3H13,ZBTB43,LMO3,ATP10B,RGL1,STXBP1,SYNE2,DNAJC9,CAMTA1,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,TRPS1,PPIL6,VLDLR,LYPD6,LAMP5,CADM2,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-577:PITA hsa-miR-577:PITA_TOP PITA 3.99E-64 2.24E-60 2.15E-63 1.98E-62 140 672 "RALGAPA1,USP31,KLHL13,PCDH19,OSBPL8,ARHGAP20,FAM135A,AMPD3,APC,USP37,CDC14B,RGS20,CDK13,CHRD,ATP2A2,ATP2B2,MYOM1,CALB1,USP6,SLC16A4,LARGE1,MAGI1,CHN2,LHX2,QKI,CNN3,SH2B1,SOCS5,RIMS2,USP6NL,DOCK4,HDAC4,SPOCK2,DBI,RHOBTB1,WDR20,CASP8AP2,PDCD6IP,SNX29,MBNL2,KMT5B,TENM1,PLEKHA1,RGS17,TMEM35A,EPHB1,EYA1,NRN1,ACSL4,TAOK3,FKTN,AFF2,KHDRBS3,MPP6,OGA,C15orf41,SRRM4,CPLX1,AHDC1,PPARGC1A,TOX3,TNRC6A,GPR37,ADAMTS6,TOX2,MIER3,HLF,NEGR1,SOWAHA,IGF1,STXBP5,KTN1,LIG4,SFXN5,MAP2,LRP1B,KITLG,MKLN1,NRCAM,IGSF11,CLDN11,GPR137C,CNTN3,PCDH8,PRTG,GNG2,KCTD15,PLCL1,SMOX,TRHDE,LRP12,DRAM2,DIRAS2,PTPRD,PTPRN2,PTPRO,TMEM145,RDX,SLC25A36,PBRM1,SETD5,FBXW7,SPIN3,CLIP1,ZNF821,KIF21A,PPM1E,SHMT2,FAM81A,CPEB4,MBD5,SOX11,SP4,MYCBP2,PEG10,CDK19,LMO3,ARHGEF9,PLCB1,SYP,AGTPBP1,ZEB1,PUM2,SIRT1,ZFPM2,HEY1,KAT6B,BCL2L13,ZNF711,MICU3,ZBTB38,REEP1,SH3GLB2,SMARCAD1,MAP3K12,CADM2,EVI5,KAT6A,HNRNPA3,CPNE4" MicroRNA hsa-miR-543:PITA hsa-miR-543:PITA_TOP PITA 4.73E-64 2.64E-60 2.54E-63 2.34E-62 130 575 "KCNH8,FMNL2,ADCY6,PWWP2A,KLHL13,PCDH19,OSBPL8,FAM135A,CDC14B,CASK,MARCH3,STX16,ADGRB3,BCL7A,JAZF1,WASF1,CALB1,CAMK2G,SPAG9,ARHGEF2,CDH2,DCLK1,MAGI1,DLGAP2,CHN1,CHN2,NRXN3,QKI,AKAP7,AKAP6,GAL3ST1,AHCTF1,MYRIP,SLC35F1,CLOCK,OSBPL3,CTH,MATR3,YTHDC1,ELMSAN1,MFAP3L,ZC3H11A,SACS,SPOCK3,DLX1,NR1D2,CPEB2,GOLT1B,KLHL5,PAN3,EPHB1,EYA1,SEC24B,FGF12,MEX3B,PCYOX1,MEGF11,GATM,GGT7,PPARGC1A,TTBK1,TCERG1,SPIN1,GRB10,CIT,FAM222A,BACH2,NEGR1,HSF2,SOWAHA,IPO5,LIFR,MEIS2,KITLG,AFDN,MYCN,NELL2,CNOT4,NRCAM,PCSK1,PRTG,SERPINI1,SCHIP1,PPP2R2C,CEP41,CNNM2,PTCH1,PTPRB,PTPRD,PTPRE,PID1,FIGN,PBRM1,ZFHX4,ALG9,SCN2B,BTBD3,CPEB4,SNAP25,LMBRD1,TEX2,RBM26,LMO3,LARP4,RGL1,SEPT3,PRRC2C,MTCL1,CAMTA1,TCF4,DMXL2,TRIM2,SYNE1,SIRT1,LRRC8A,CSMD1,TRPS1,TSC1,UBE3A,PCDH20,ZIC1,ZIC2,REEP1,LAMP5,ZFAND5,PRDM10,KAT6A,RNF146,SOCS4,SENP7" MicroRNA hsa-miR-92b:mirSVR_highEffct hsa-miR-92b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.01E-64 2.80E-60 2.69E-63 2.48E-62 158 863 "SYN3,NCKAP5,TMCC3,KIAA1211,MARCH4,FAM135A,PITPNM2,DPP10,ATP2A2,ADAM23,ADGRB3,MPDZ,HCN2,SYNJ1,CACNA1I,CA8,KALRN,CAMK2A,MTMR7,SOCS6,NDST3,NRXN3,HECTD1,CNRIP1,FAM171B,CRHBP,LRIG1,SOCS5,SLITRK5,ERC2,APPL1,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,PLPPR4,CDON,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,POLK,ATP13A4,SLC37A3,ATP6V1H,ZNF605,NSG1,ABLIM2,GAA,B4GALNT1,IQGAP2,GHR,SPIN1,GLYR1,GPD2,TPPP,DIDO1,HAS2,MIER3,HNMT,MSL1,RBPJ,SLC6A17,C2CD4C,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,GPR137C,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,TRHDE,STRN3,ING3,CEP41,TMEM260,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,FNIP1,CPEB3,MYO18A,CNKSR2,NUBPL,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PDZD2,MYCBP2,TEX2,PBLD,ITPRID2,ELOVL4,RGL1,SYN2,SYPL1,SYT1,CAMTA1,DOCK9,SIK3,SYNPO2,TRIO,SGK3,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,MFF,EVI5,RNF103,NAV3,RGS7BP,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-30c-1*:mirSVR_highEffct hsa-miR-30c-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.00E-64 3.92E-60 3.76E-63 3.46E-62 184 1167 "NDRG2,ADD2,PWWP2A,KCTD16,WDR35,AK2,C1QTNF3,ALCAM,MARCH4,PCDH10,BIN1,LRFN1,CDC42BPA,TNRC6C,SEMA4G,ADAM15,SEC11C,ARHGEF7,JAZF1,VXN,RUNX1T1,LDB2,CHN2,TAOK2,IQCK,FAM149A,AKAP6,COL9A3,CREM,HAPLN1,RGS6,LRRC3B,RUBCN,MYADM,KATNAL2,DCAF8,MAML1,ZC3H11A,RHOBTB1,GRIN3A,SLC29A4,SHANK1,DTNA,MAMLD1,ABCC5,DNM1L,E2F6,AASDH,WDPCP,HIPK3,SUGP2,EGFR,MBNL2,KCTD3,EPB41,EPHB1,RACK1,PPP1R1B,POLR1B,SPSB4,FGF13,FHL1,NELFCD,PDLIM5,USP21,GABBR1,ERAP1,C15orf41,DISC1,SRRM4,TUBGCP4,ADAM28,GGT7,MALT1,LOXL3,WDFY3-AS2,PRUNE2,MCHR1,ATP2B1-AS1,PLCD4,RABL2A,SOX21,RNFT2,ADAMTS6,FRMD5,ARHGAP36,MIER3,AGBL5,HNF4G,LRRCC1,MT1M,P2RY13,NEFM,NF1,TBC1D25,IGSF11,OPA1,DPY19L2P2,GNG2,NLGN3,PLCB2,MTRF1L,PURG,CEP41,RELN,CNTLN,TMEM260,PTPRH,PTPRO,ZCWPW1,ZNF493,GTDC1,TMLHE,EXD2,KIRREL1,SCN8A,SGK1,KIF16B,CPEB3,FNDC3A,NLGN1,SLC8A1,ATF7IP,ZKSCAN3,SMARCC2,SNCA,CABCOCO1,DOP1A,ZSWIM8,ZNF423,SPTAN1,DDN,ATP10B,CLASP2,ZC4H2,NKAIN2,STAU1,SEPT8,SULF2,SYNE2,SYP,TACR1,MTCL1,KLHL4,RPGRIP1L,OBSL1,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,CYB561A3,C18orf54,ITGB3BP,AKTIP,SLC44A1,NR2E1,TPM1,NEIL2,PRR18,SGK3,TUBB1,UBE3A,FLRT2,PLEKHH2,KLC2,GUSBP1,ZIC1,ZNF19,SPIRE1,FTSJ1,MEIS3,HPS4,SLC17A7,UBE3B,ACTR3B,KLHDC1,NETO2,FAM198A" MicroRNA hsa-miR-3194:mirSVR_lowEffct hsa-miR-3194:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.45E-64 4.17E-60 3.99E-63 3.68E-62 208 1471 "VWA5B2,KCNH8,EMILIN3,NDRG2,UNC5A,MTA3,KIAA1324,SYT13,AMPD3,MAP4K3,PPFIA4,PPFIA3,LGR5,PRX,MARK4,CCAR2,TMEM108,CHID1,ATP1A3,N4BP2L1,ADAM15,RGS11,BID,KSR1,JAZF1,AP1M1,CA8,CA12,CALB2,CALM1,CAMK2B,CAPN3,SPAG9,CBR1,P2RX6,NUMBL,TAOK2,FBXO7,HECTD1,PCYT1B,SMARCAL1,CREM,AATK,SNCAIP,CSF1R,RGS6,CSNK1E,GALNT9,CST3,ARHGEF4,GPSM1,DCAF8,DGKG,TMEM130,LYPD1,POM121,SV2B,HS3ST2,SLC29A4,DPH1,SLC25A18,DTNB,TOM1,DNAJB6,ABCC5,EDNRA,CNNM1,HEYL,SUGP2,APH1A,MRO,RASA4,TNK2,MRPL37,ADGRV1,EZH1,FCGR1A,FCGRT,FGF1,BAIAP2,HPCAL4,NOP56,SDCBP2,GALNT15,INPP5K,GATM,SRCAP,SULT1C4,ARFIP1,GHR,GLI2,STARD3,LILRA2,PLCD4,ADAMTS13,SERP2,RNF165,RABL2A,RNFT2,FRMD3,FAM95B1,MYLK2,RBPJ,TJAP1,ZNF678,KCNF1,LSS,ASPRV1,SCAMP5,AFDN,BLOC1S2,NRBP2,N6AMT1,MXI1,LAYN,HNRNPM,NF1,NOVA1,DNHD1,NPTX1,NPTX2,IGSF11,CDK18,PDE1B,PFKFB4,FAM216A,SLC25A23,PLXNB1,EXOSC10,RETREG2,POLG,SH3KBP1,NKAIN4,PPP5C,RASGEF1B,PRKACB,PRKCB,HYDIN,MASP1,ZSCAN32,PTPRG,PTPRN2,RIPOR1,NKAIN1,TUG1,CEP97,CCDC40,RAD51D,SUSD4,ZFHX4,ZNF532,ADAL,KCNIP3,RTN1,ZNF568,MAPK12,SATB1,CSRNP3,PRCD,SCP2,TNFRSF19,MYO18A,NLGN1,ST8SIA1,ARHGEF40,SMARCD3,INTS9,ANKRD36,SNRPN,BDP1,ZSWIM8,NKAIN2,MPRIP,KLHL7,SUPT5H,ADAMTS17,ARC,MMS19,TACC1,PDLIM2,SMG6,TPCN2,RPGRIP1L,DOCK9,TNS2,VWCE,AKTIP,GALNT17,ARL10,NACC2,TPM1,C9orf85,SMUG1,TRPM2,LAT2,WRN,LGI4,ZNF19,TRIM9,CRB2,POLR3H,AMZ1,FTSJ1,SLC30A3,RNF103,HNRNPA3,FXR1,JPH3" MicroRNA hsa-miR-199a-3p:mirSVR_highEffct hsa-miR-199a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-63 6.56E-60 6.27E-63 5.78E-62 166 958 "ABCF1,KCNH8,KDM5D,KLHL13,KCTD16,HACE1,OSBPL1A,TAOK1,ALCAM,ANK2,PHF12,UPRT,RGS20,CADPS,ZBTB10,DST,SYNJ1,FUBP1,CABP7,KALRN,RUNX1T1,MTMR7,DCLK1,CDO1,TIGD7,CFL2,SRSF11,MS4A7,NDST3,QKI,MAP4K4,ARMC8,COL4A5,LETMD1,MYRIP,FAM171B,RNF14,LRRC3B,OSBPL3,VAC14-AS1,PHF14,ARHGAP24,WDR20,FAM107B,USP3,SLC29A4,DTNA,ECM2,EBF1,EDN1,FAM13A,EIF4G2,CALCRL,EPB41L2,LRRC17,GPHN,CEP85L,FCGR3A,ZSCAN30,GORAB,MED12L,PSD2,TMEM107,HVCN1,PDLIM5,MSANTD4,HHIPL1,OGA,CHL1,TUBGCP4,TUBA8,SULT1C4,COPS8,ZNF638,GPD2,LPAR4,GPR37,ZHX1,MIER3,HNMT,IFI16,ZNF678,KCNH2,KCNN2,KIF2A,KTN1,HECTD2,NCOA7,MBNL1,MEIS2,SRSF12,ADAM22,NRBP2,NCAM2,NF1,NOVA1,DNHD1,PDE4B,FAM216A,PLIN1,PPP2R5E,CEP41,PRKCB,DCHS2,CNTLN,BDNF-AS,PTPRE,PPP2R3C,MARCH1,CEP97,OXR1,RADX,RGS4,PRIMA1,RORB,RPL15,ZC3H14,PTGR2,SCN8A,SCP2,ZFP30,WDR47,CCDC88A,ELMO2,CPEB4,SMARCC2,ANKRD36,LMBRD1,USP33,DOK5,KDM3A,SP2,LMO3,CLASP2,SS18,PRRC2C,PLCB1,SYP,SYPL1,ANKRD12,DMXL2,TRIM2,USP32P1,AP4E1,SYNPO2,SGK3,TUBB1,BCL2L13,VLDLR,CLDND1,XPO1,MICU3,ATP6V0E2,SPIRE1,TMEM178A,KCNAB1,RGS7BP,RTN4,SMIM8,HNRNPA3,CASC15,ADAMTSL3,FXR1,DPF3,GAN,FAM198A" MicroRNA hsa-miR-199b-3p:mirSVR_highEffct hsa-miR-199b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-63 6.56E-60 6.27E-63 5.78E-62 166 958 "ABCF1,KCNH8,KDM5D,KLHL13,KCTD16,HACE1,OSBPL1A,TAOK1,ALCAM,ANK2,PHF12,UPRT,RGS20,CADPS,ZBTB10,DST,SYNJ1,FUBP1,CABP7,KALRN,RUNX1T1,MTMR7,DCLK1,CDO1,TIGD7,CFL2,SRSF11,MS4A7,NDST3,QKI,MAP4K4,ARMC8,COL4A5,LETMD1,MYRIP,FAM171B,RNF14,LRRC3B,OSBPL3,VAC14-AS1,PHF14,ARHGAP24,WDR20,FAM107B,USP3,SLC29A4,DTNA,ECM2,EBF1,EDN1,FAM13A,EIF4G2,CALCRL,EPB41L2,LRRC17,GPHN,CEP85L,FCGR3A,ZSCAN30,GORAB,MED12L,PSD2,TMEM107,HVCN1,PDLIM5,MSANTD4,HHIPL1,OGA,CHL1,TUBGCP4,TUBA8,SULT1C4,COPS8,ZNF638,GPD2,LPAR4,GPR37,ZHX1,MIER3,HNMT,IFI16,ZNF678,KCNH2,KCNN2,KIF2A,KTN1,HECTD2,NCOA7,MBNL1,MEIS2,SRSF12,ADAM22,NRBP2,NCAM2,NF1,NOVA1,DNHD1,PDE4B,FAM216A,PLIN1,PPP2R5E,CEP41,PRKCB,DCHS2,CNTLN,BDNF-AS,PTPRE,PPP2R3C,MARCH1,CEP97,OXR1,RADX,RGS4,PRIMA1,RORB,RPL15,ZC3H14,PTGR2,SCN8A,SCP2,ZFP30,WDR47,CCDC88A,ELMO2,CPEB4,SMARCC2,ANKRD36,LMBRD1,USP33,DOK5,KDM3A,SP2,LMO3,CLASP2,SS18,PRRC2C,PLCB1,SYP,SYPL1,ANKRD12,DMXL2,TRIM2,USP32P1,AP4E1,SYNPO2,SGK3,TUBB1,BCL2L13,VLDLR,CLDND1,XPO1,MICU3,ATP6V0E2,SPIRE1,TMEM178A,KCNAB1,RGS7BP,RTN4,SMIM8,HNRNPA3,CASC15,ADAMTSL3,FXR1,DPF3,GAN,FAM198A" MicroRNA hsa-miR-1288:mirSVR_lowEffct hsa-miR-1288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-63 7.07E-60 6.75E-63 6.22E-62 176 1075 "PLEKHH1,ADORA1,ESYT2,DPY19L2P4,FAM135A,BIN1,OGT,MYH7B,SUGT1P4-STRA6LP-CCDC180,TNRC6C,USP37,SFMBT2,SEMA4G,IGDCC4,NUMB,BMP7,SYNJ2,MTMR3,C5,CACNB4,CALB2,CAMK2G,ARHGEF25,KRIT1,ARHGEF1,SEPT7,CBARP,PLEKHB1,B4GALT6,STOML1,FBXO7,SRP14-AS1,LY86,IQCK,TBPL1,ZNF521,NECTIN3,CRMP1,ANKRD44,AATK,CSF1R,CSNK1E,RIMS4,PHF14,GREB1,FAM131B,ARHGAP32,DAPK1,DGCR5,MFAP3L,FBXL5,DDX46,POM121,SPOCK3,SGSM2,CHRDL1,EXOG,DNM1,HS3ST2,DMTF1,ACOT8,E2F5,AASDH,FSD1L,EIF4G2,DCTN4,EMX2,VPS13B,RASL12,CEP78,SUCO,PCYOX1,FLT1,NOP56,NBEA,KHDRBS3,CELF1,ABLIM2,GABRG1,B4GALNT1,IP6K3,DISC1,GGT5,RAB30,PRUNE2,KAT7,ZBTB49,GABARAPL2,IGF1,KNDC1,IL6ST,KCNK3,A1BG-AS1,STMN1,MAP2,MATN3,MBP,XRRA1,MXI1,CCDC13,NEK1,CNOT4,PCBP3,GPR137C,PCDH9,ZNF655,PLTP,MAPKAP1,PPP3CA,WBP1L,RASGRF1,RASGRF2,RDX,DUSP15,FIGN,KIF7,CCDC25,SPIN3,ADAL,STK32B,RTN1,STX1B,RYR3,ZNF331,MAPK12,ATXN7,ZNF821,MYO18A,FNDC3A,KANSL3,RADIL,ELMO2,SLC22A4,INTS9,IFT122,MYO16,USP33,SOX15,UHRF1BP1L,POGZ,CEP68,NSFL1C,CAMTA1,ADGRL3,KIAA1107,TBCEL,TPCN2,SZT2,FAM189A1,TNS2,CYB561A3,VWCE,FAM200B,DICER1,ZFPM2,BEX4,KAT6B,WBP2,PPIL6,HSPBP1,SLC35A4,FLRT2,CCDC136,VLDLR,WIPF1,GUSBP1,ZNF19,ZNF138,EML6,ZXDA,PPP1R3F,FZD3,FAM219B,JMJD1C,KLHDC1,FRMD6" MicroRNA hsa-miR-128:mirSVR_highEffct hsa-miR-128:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.48E-63 8.28E-60 7.90E-63 7.28E-62 177 1088 "RALGAPA1,ADRB2,AK2,SMIM17,SUGT1P4-STRA6LP-CCDC180,APBA2,TMEFF1,PDE8B,MARK4,RNF182,DPY19L3,DOCK11,TTLL9,C5,PTBP2,CAST,SPAG9,NFS1,LRRFIP1,MAGI1,COPB2,SRSF11,SOCS6,C4orf33,HECTD1,IGLON5,ARMC8,CABP1,LETMD1,RNF14,CSF1,VCAN,SOCS5,ERC2,RIMS2,BOC,GAPVD1,ARMCX4,SV2B,DNM1,DMPK,HS3ST2,USP3,DMTF1,ARRDC4,DTNA,ABCC5,EDN3,EDNRA,YAF2,EBI3,EGR3,TNK2,MTSS1L,EPHB1,SRRM1,FCGR1A,FGF1,PRKAG2,SUCO,UBE2E3,ATP13A4,OGA,MEGF11,GAD1,DISC1,GCNT2,GHR,RUNDC3A,ZNF638,GPD2,DIDO1,KAT7,MAP4K5,HMGCL,HSPA1L,SMAP1,MSL1,IL6ST,CDH20,CREG2,STXBP5,CLEC18A,MAP2,AQP11,NEK1,NF1,NFE2L2,NME4,NPY,NTRK3,TBC1D25,ZNF827,PCDH9,CDK18,PRTG,PDE3A,PDE4D,SLC10A4,GNG2,PFKFB4,OLA1,ZNF655,RASGEF1B,SLC26A11,DIRAS2,RELN,VPS13C,DEF8,CNTLN,PTCH1,MTMR10,FAM66C,FAM184A,RBBP6,RDX,RET,REV3L,MRPS18A,SETD5,KLHDC8A,ALG9,ELP2,FAM192A,CASC3,SH3GL3,PPM1E,R3HDM2,CNKSR2,WDR37,SLA,BTBD3,RADIL,CCDC88A,ELMO2,SLC22A4,RCOR3,SNAP25,SNRPN,SP2,SP4,KDM4C,ZC3H13,CLASP2,TROVE2,POGZ,SS18,NXT2,ELOVL4,ADHFE1,SEPT3,KLHL7,SYNE2,VPS13A,PLCB1,SYT1,TACR1,CAMTA1,MCF2L,PDLIM2,TCEA1,ZEB1,TPCN2,FRYL,SIRT1,TPM1,TTC3,FAM155A,OSBP2,ZBTB14,MAP3K12,MDH1B,DOCK8,RTN4,CASC15,IFT88,NETO2" MicroRNA hsa-miR-656:PITA hsa-miR-656:PITA_TOP PITA 1.64E-63 9.15E-60 8.73E-63 8.03E-62 138 659 "NDRG3,FMNL2,AXIN2,HECW2,PCDH19,ARHGAP20,OGT,USP37,TMEFF1,ADGRB3,BCHE,NRP2,JAZF1,KALRN,RUNX1T1,ZNF501,KRIT1,LRBA,SEPT7,MAGI1,CLGN,FOXN3,SOCS6,B4GALT6,NRXN3,TMEM184B,ARHGEF6,GDA,CS,SOCS5,RIMS2,GAPVD1,HDAC4,DGKG,ZNF804A,RHOBTB1,FAM107B,DMD,NYAP1,NR1D2,RASGRP1,MBNL2,EGR3,RCAN2,ETV1,EYA1,ST6GALNAC3,CHL1,GABRB3,MSTN,SPIN1,RAB30,HTATSF1,LOXL3,BACH2,HNF4G,NEGR1,IL6R,KCND2,SMAD1,MAP2,MATN3,LRP1B,MEF2C,MGAT3,HS6ST3,MYT1,NCAM2,NF1,CNOT4,NOVA1,NPTX1,PCDH9,PCSK1,CDK18,GNG2,PIK3C2A,PIK3R1,CCSER2,XRN1,PMP22,MINDY2,SNRK,PTCH1,PTPRB,PTPRD,OXR1,RDX,ROBO2,RORB,RPE,ZC3H14,RMI1,SEMA6D,ATXN2,ZFP30,KIF21A,PPM1E,CPEB3,FNDC3A,CCDC88A,TET1,CPEB4,SNAP25,FAM219A,PDZD2,SOX11,ARHGAP26,RBM26,CLASP2,POGZ,LARP4,SS18,SEPT8,PLCB1,SYT1,ANKRD28,TACC1,TBL1X,SATB2,RPGRIP1L,SLC35G2,FRYL,TEK,ERCC6L2,TNS1,NR2C2,TRPS1,UBE2H,WNT7A,MICU3,CADM2,NAV3,RGS7BP,PHTF2,FRMD6,SOCS4,GAN" MicroRNA hsa-miR-150:mirSVR_highEffct hsa-miR-150:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.38E-63 1.33E-59 1.27E-62 1.17E-61 151 796 "ACADM,NCKAP5,SYS1,PWWP2A,LRFN2,KCTD16,TBC1D14,FAM135A,PKP4,APC,EPB41L5,PHYHD1,PPFIA3,TMEM108,ZNF582,ADAM23,CFLAR,CACNA1G,CACNA2D1,PTBP2,CAST,RUNX1T1,CERS5,CD38,ZMYM4,DLGAP1,FAM149A,AKAP6,SEC31B,HINFP,SUSD5,PDE4DIP,CTH,RIMS2,KATNAL2,IST1,ARMCX4,FBXL5,SV2B,DMTF1,PHC2,APH1A,KMT5B,PLXNC1,GOLGA7,KCTD3,EIF5,PLEKHA1,ING4,C3orf18,EPB41,DENND4A,MRPL10,CLVS1,FAM198B,ACSL4,PTK2B,FCGRT,FER,GTF2IRD2,NBEA,SMC2,SPECC1,ATP6V1H,CELF1,GAA,GABBR1,GABRG2,SULT1C4,PPARGC1A,TNRC6A,MAP7D2,CCDC184,RASSF8,NEGR1,IRF8,IFI16,C2orf72,SCIN,KCNB1,KCND1,IPO5,LIMS1,PIK3AP1,MBD1,COL28A1,NFE2L2,NRCAM,PCSK1,PDPK1,SMIM7,PRKACB,MASP1,CNTLN,PTPRE,PTPRH,MARCH1,CEP97,ZCWPW1,RASGRF2,TRIM68,RGS12,RNASEL,CCDC25,RORB,MRAP2,NEK11,SPIN3,ZC3H14,KCNIP1,ZNF331,SCP2,ZFP30,FAM102A,SHC4,ST6GAL1,NUBPL,WDR37,ABLIM3,SLA,DHX30,SLC8A1,FNBP1,ERC1,CEP68,VPS13A,SYP,SYPL1,COBL,FAM208A,ZEB1,DOCK9,TEK,SMUG1,RUNDC3B,TRPS1,RPL7L1,OSBP2,MTCH1,CLDND1,ZNF711,TRIM9,ZNF138,SLC17A7,HRASLS,AMN1,DOCK8,UBE3B,PHTF2,RNF146,GAN" MicroRNA hsa-miR-15b:PITA hsa-miR-15b:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,ARHGDIA,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-497:PITA hsa-miR-497:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,ARHGDIA,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-195:PITA hsa-miR-195:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,ARHGDIA,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-424:PITA hsa-miR-424:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,MINDY2,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-15a:PITA hsa-miR-15a:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,ARHGDIA,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-16:PITA hsa-miR-16:PITA_TOP PITA 2.62E-63 1.47E-59 1.39E-62 1.28E-61 147 754 "GALNT13,AXIN2,USP31,ADRB2,AP2A1,ARHGAP20,MARCH4,OGT,ARHGDIA,STK33,ZBTB10,SLC4A4,ATP2B2,BCL7A,SYNJ1,FUBP1,LDLRAD4,CAMK2G,RUNX1T1,DCLK1,SRSF11,SOCS6,CLCN3,QKI,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,KCTD8,IST1,IP6K1,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,TSPAN5,SEMA3D,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,ETV1,EYA1,EZH1,ACSL4,SUCO,AGAP2,AGAP3,SYT3,CSPG5,TPPP3,SESN1,PCDH17,GHR,FERMT2,TMEM121B,HAS2,ZHX1,BACH2,ACOT7,SLC35G1,KIF5A,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,LRRN3,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,PID1,TMEM255A,RBBP6,ZFHX4,ZNF532,FBXW7,SALL1,SEMA6D,ATXN2,SCN8A,HSPA4L,PUF60,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,FAM81A,WDR47,SLC12A2,RCOR3,SNAP25,TMCC1,FAM219A,ZHX3,TSPYL2,STX1A,PRRC2C,ARHGEF9,SYN2,SYPL1,SATB2,TRIM2,SYNE1,FRYL,DICER1,SLC44A1,CSMD1,NR2C2,WNT7A,KLC2,ZIC1,EVI5,STOX2,TUBA1A,KCNAB1,ADAMTSL3" MicroRNA hsa-miR-379:mirSVR_lowEffct hsa-miR-379:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-63 1.72E-59 1.62E-62 1.50E-61 163 930 "CLK4,ABHD6,C3orf14,KLHL32,TMCC3,BRAP,PLEKHH1,ADRB2,AGT,OSBPL1A,BBOX1,ZFAT,PHF12,APAF1,APBB2,PPFIA3,TMEFF1,SLC4A4,ADGRB3,BBS2,KSR1,DST,SYNJ2,SCAPER,CALB2,CAST,CD86,LRBA,SEPT7,SRSF11,NDST3,AKAP6,MAGED1,ABI3BP,AHCTF1,CNRIP1,CRY2,CRYM,CS,LRIG1,PITPNM3,GREB1,DCAF4,RUBCN,GAPVD1,ARHGAP24,DGKB,GIT2,DNAL1,ZBTB24,PLPPR4,WDR20,EXOG,RAB39B,SLC29A4,DMTF1,DPYSL2,SLC25A18,DTNA,E2F5,PHF20L1,APH1A,EGR3,EPB41L2,DNAJC27,ARMCX1,CLVS1,SLC9B2,FGF1,PRKAG2,MEX3B,FOXF2,PDLIM5,ATP6V1H,MSANTD4,MEGF10,GABRA3,GAD1,C15orf41,ACSS1,GATM,IGSF5,MSTN,PPARGC1A,DHRS4,GPD1,GPD2,FAM107A,HAS2,ZDHHC15,MSL1,KIF2A,STXBP5,HECTD2,ZNF667-AS1,MAT2A,MEIS2,MYO7A,MYO9A,IGSF11,OGG1,PCSK5,PDE1C,OLA1,GPSM2,PLEC,PNMA3,MAGEL2,PPP2R5E,MASP1,PIGG,HKR1,RET,FIGN,DCUN1D2,ROBO1,KIAA0895L,ATP8B4,STK32B,HSD11B1L,ATXN2,CASC3,ST8SIA1,KANSL3,ELMO2,CXXC4,GKAP1,MAST1,MBD5,SNRPN,SP2,KDM4C,RBM26,LMO3,ATP10B,ITPRID2,LARP4,SYN2,COBL,TACC1,CAMTA1,EXOC7,PDLIM2,TCF4,RPGRIP1L,PCDHB4,TNS2,PMS2CL,RIMBP2,HIRA,GORASP1,UGT8,PLEKHH2,WIPF1,KLC2,XPO1,ELFN1,SMARCAD1,DNALI1,DOCK8,PHTF2,JMJD1C,FRMD6" MicroRNA hsa-miR-621:mirSVR_lowEffct hsa-miR-621:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.63E-63 2.03E-59 1.92E-62 1.77E-61 149 777 "ACADM,FMNL2,KLHL32,PCDH19,OSBPL6,WDR35,CC2D2A,AK2,ADGRF5,FAM135A,ZFAT,LRCH2,FGD2,PPFIA4,UPRT,USP37,LGR5,AQP6,CDK10,ARNTL,CALM1,USP2,TIGD7,CNN3,SEC31B,ABCG1,CST3,ARHGAP32,RASSF2,TBC1D5,KCTD8,MAML1,TMEM170A,AIF1L,ARMCX4,DMD,DPP6,DRP2,PDCD6IP,ECM2,TOM1,DNM1L,ANKRD46,OPTN,PHF20L1,MRO,EIF4G2,SRRM1,CEP85L,EXTL2,MRVI1,NRN1,FCGRT,STRADA,MED12L,AMOTL2,POLK,FOXO3,ANKFY1,CAMKK2,KHDRBS3,CELF1,GALC,MTHFD2,GATM,ALDH1L1,MSL3,STARD3,RAB40B,LOXL3,FERMT2,TDRKH,TOX2,PADI2,FRMD3,FAM95B1,MYLK2,NKD1,KIAA1755,INSM1,KCNJ16,CREG2,LINC00634,LAMP2,MAP6,MAT2A,AQP11,CHIC1,MEF2C,MEIS2,KITLG,MMP16,LYRM9,MYO6,MYO7A,NCF2,SETD4,GPR137C,DPY19L2P2,SNX10,GPSM2,JAKMIP1,POU6F1,MINDY2,RANBP3L,PRKCB,PIGG,CNTLN,PTPRD,PTPRE,PEX2,TUG1,CEP97,ENOX1,RBBP6,RDX,ZMAT4,RNASEL,NEK11,FBXW7,ATXN2,SUPT20H,TRA2B,ARX,CPEB3,KBTBD4,SLC12A2,SLC14A1,MBD5,SNRPN,KDM4C,RBM26,ZC4H2,NSFL1C,ATMIN,TPCN2,TCF12,GPRIN3,SIRT1,AP4E1,RGMB,FAM155A,WIPF1,ZBTB14,ZNF24,REEP1,EPM2A,ACTR3B,ST8SIA2" MicroRNA hsa-miR-4313:mirSVR_lowEffct hsa-miR-4313:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.77E-63 2.67E-59 2.52E-62 2.32E-61 189 1243 "ASPHD1,SYS1,KDM5D,XKR4,ADCY6,BRAP,KIAA1324,LTBP4,FAM135A,ZNF687,BCAS1,MADD,IGDCC4,SPTBN4,CADPS,LINC00173,PDE8B,STK33,RASL11B,DPY19L3,ADAM23,TTLL9,RGS11,CFLAR,BMP7,SYNJ2,GPC2,CA12,HAP1,SLC25A14,CAST,CARS,USP2,CD86,ENTPD6,AP4M1,ARHGEF2,L3MBTL4,DIS3L,EPS15L1,PPT2,MYL6B,HECTD1,WHRN,SMARCAL1,ZNF385A,SH2B1,HAPLN1,CS,SEC24C,IPCEF1,PDE4DIP,PPP1R16B,UBXN2A,ZFYVE16,DAPK1,AIF1L,KLHL3,DMD,SLC25A18,DNM1L,KRBA2,E2F6,SEZ6L2,WDPCP,KLHL5,ING4,C3orf18,SLC43A2,SPEG,MRVI1,EZH1,DLC1,KAT8,SPSB4,POLK,SCARA3,AGAP2,EVL,STAMBP,CAMKK2,ZNF605,STAU2,AP4B1,BRSK1,ZNF44,SEPT9,MSTN,GFER,GGT5,TTBK1,TNRC6A,AIFM3,STARD3,MAP7D2,LILRB4,GRIA2,ADAMTS13,LINGO1,TNFAIP8L3,INSYN1,SYNPO,SHISA6,C2orf72,ITPKA,ITPKB,STXBP5,L1CAM,HECTD2,LSS,MAP4,MATK,NRBP2,THYN1,LYRM9,HNRNPM,NEFM,DNHD1,PCBP3,TBC1D25,P2RX7,PDE4B,TMEM38A,NECAB2,SEPT4,TATDN3,NKAIN4,MAPK10,WBP1L,WDR25,CNTLN,TMEM260,PTPRH,RASGRF1,RET,RIC8B,PBRM1,CYB561D1,CCDC102B,SNX22,ZC3H14,EMID1,MEG3,DGLUCY,ATXN2,MRAS,RASA3,FRMPD1,FERMT1,AMBRA1,ST6GAL1,PEX26,FAM214B,SLC6A8,RADIL,SLC9A5,SLC11A1,SLC12A4,SLC14A1,SNRPN,TSNAXIP1,IQSEC2,TROVE2,STAC2,SUPT5H,ALG1,SYNE1,PHF24,TNS2,SIK3,RNF216P1,TK2,LRRC8A,TMPO,FAM124A,R3HDM1,ELP5,RPL7L1,UBTF,NPDC1,ZIC1,ZNF708,AGMO,REEP1,MAP3K12,DNALI1,PCBP4,FAM219B,GAN" MicroRNA hsa-miR-129*:mirSVR_lowEffct hsa-miR-129*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.31E-63 2.97E-59 2.80E-62 2.58E-61 177 1097 "ADD2,PWWP2A,ESYT2,ZNF578,ADGRF5,C1QTNF3,SYT13,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,CDK13,MARK4,NCOA1,RASL11B,TTLL9,CFLAR,KSR1,SCAPER,MYRF,LDLRAD4,KALRN,CLDN10,LARGE1,RCBTB2,SRSF11,CHN2,RAB28,PLAA,MAP4K4,ARHGEF6,AKAP6,AKAP5,RCHY1,FAM171B,SH2B1,AKAP12,SEC24C,OSBPL3,DCAF4,RUBCN,HDAC9,SPOCK2,IP6K1,AIF1L,ARMCX4,MYEF2,TIAM2,RUSC2,ALKBH8,DNM1,HS3ST2,ECM2,PHC2,TMTC1,FRY,EBI3,VPS13B,MRPL37,GORAB,OLFM1,FGF13,SUCO,MEX3B,PCYOX1,C2orf88,TPK1,CAMKK2,ATP2C1,ERGIC3,CELF1,MSANTD4,TVP23A,GABRG1,B4GALNT1,LRRC37A6P,KDM2B,GPD1,CACFD1,GRIN2C,CLASRP,RNF165,TOX2,HMGCL,SHISA6,MSL1,TJAP1,IL12A,ITPKA,GPR62,STXBP5,CYP27C1,TTYH2,SYTL4,MAP4,AFF1,XRRA1,ADAM22,MSR1,ZNF862,SFR1,NEK1,CNOT4,NTRK2,TBC1D25,PDCD2,PRTG,NALCN,SEMA5B,PLXNB1,EXOSC10,POLG,PPP2R5E,RASGEF1B,PRKCB,MAPK3,PSD,QRICH1,ELOVL2,PTPRG,PTPRO,RAP1GDS1,TRIM68,GTDC1,UBR7,ZNF532,GSTCD,ROBO1,SNX22,ATAT1,ZNF568,STX1B,FAM192A,SEC14L1,KIF21A,FBXO11,R3HDM2,CNKSR2,EPN2,SLC6A8,SLC14A1,BTBD7,CXXC4,SNRPN,NMNAT2,STAU1,CEP68,PHLDB1,SEPT3,NSFL1C,VPS13A,TMEM150C,SYT1,COBL,KLHL4,CLASP1,SYNE1,USP32P1,CYB561A3,AP4E1,MTMR14,TMPO,RGMB,ELP5,NEIL2,AMACR,UBE3A,RICTOR,ZBTB38,AMZ1,MEIS3,DNALI1,STOX2,HPS4,GAL3ST3,NAV3,HNRNPA3,FBXO36" MicroRNA hsa-miR-214*:mirSVR_lowEffct hsa-miR-214*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.92E-63 3.31E-59 3.12E-62 2.87E-61 196 1333 "DGCR6,SYN3,ASIC1,KDM5D,UNC5A,PWWP2A,KIAA1324,WDR35,SRPX,ZNF687,SUGT1P4-STRA6LP-CCDC180,PKP4,CDK10,SEMA4G,PRX,SPTBN4,SLC2A11,DPY19L3,RGS9,NRP2,BID,CFLAR,CA12,KALRN,VXN,CCNH,USP6,CD38,LRRFIP1,EVI5L,TIGD7,MS4A7,TAOK2,NRXN3,MAP4K4,CNR1,PICK1,LETMD1,ABI3BP,ZNF521,C2CD2,AKAP12,CRY2,C1QL2,SNCAIP,ARHGEF10,VAC14-AS1,PLXNA4,UBXN2A,ARHGEF4,RIMS2,GPSM1,DCAF4,BOC,KATNAL2,GAPVD1,ZFYVE16,CENPL,LONRF1,DGKG,GIT2,TMEM130,RHOBTB1,SNAP91,SV2B,SGSM2,KIF19,GRIN3A,DMPK,CD99L2,DTNA,DTNB,HIPK3,MBNL2,TNK2,ZNF549,KATNAL1,RACK1,FECH,SLC37A3,EFCAB2,RASL10A,TVP23A,GABBR1,DISC1,CPLX1,SULT1C4,CYP46A1,RAB30,GPD2,PCLO,GRB10,PLCD4,GRM2,MAP4K5,MAN1B1,AGBL5,CPT1C,LRRC75A,MYLK2,SOWAHA,KIAA1755,INSM1,STXBP5,LIMS1,NCOA7,ASPRV1,MID1,COMMD5,N6AMT1,MX1,LAYN,ZNF862,CCDC13,NELL2,CNOT4,NOVA1,SMIM11A,GLIPR1L2,PDCD2,CCSER2,PKD1,GPSM2,ANKRD16,SEPT4,MINDY2,PRKACB,CEP41,GRAMD1C,MASP1,WBP1L,WDR25,TMEM260,PTPRG,PTPRO,PEX2,TUG1,ZNF493,RET,GTDC1,RGS12,PBRM1,ZNF532,ALG9,HSD11B1L,ATAT1,ATXN2,SCP2,CASC3,GALNT10,SGK1,PPM1E,FRMPD1,KIF16B,DZIP1,SLA,DHX30,SLC9A5,CDK5RAP2,TTC17,SNAP25,SNRPN,FAM126B,PDZRN3,GLT8D1,PEG10,NFASC,LHPP,CLSTN2,SS18,PHLDB1,COBL,FAM208A,ADGRL3,TCF4,TRIM2,DOCK9,USP32P1,TNS2,HIF3A,CDH22,GALNT17,BHLHB9,ERCC6L2,ZNF346,TUBB1,CCDC14,GUSBP1,TRIM9,EML6,PCBP1-AS1,EMSY,STOX2,RGS7BP,UBE3B,TRAM2-AS1" MicroRNA hsa-miR-502-5p:mirSVR_highEffct hsa-miR-502-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.18E-63 4.02E-59 3.78E-62 3.48E-61 157 868 "ABCF1,ACADM,FMNL2,ADD2,BEND6,CC2D2A,SEMA6A,AMPD3,OGT,TNRC6C,SLC4A4,RIPK1,RGS9,CFLAR,CALB2,CAST,DGKI,LRBA,MAGI1,CHN1,NRXN3,CNGA3,FHL5,CNR1,AKAP7,IQCK,PCYT1B,RBM39,SH2B1,RNF14,NCOR2,GDA,SNCAIP,ARHGEF10,CST3,PLXNA4,RIPOR2,ZFYVE16,MATR3,DAPK1,ARMCX4,ALKBH8,SACS,SV2B,DTNA,ABCC5,E2F5,WDPCP,EDN1,PHC2,KMT5B,EIF4G2,PLEKHA1,PAN3,CEP85L,PIPOX,EXTL2,GMPR2,FAM198B,ACSL4,ZSCAN30,FDFT1,SEC24B,FGF12,SLC37A3,C2orf88,AKAP3,CELF1,MSANTD4,TXNL4A,RAB30,MSL3,MAP7D2,WDFY3-AS2,TDRKH,C1QL4,FAM19A2,RASSF8,MIER3,USP51,SMAP1,EID2B,MSL1,IDH3B,IGF1,ZNF678,JAK2,SLC35G1,KCNB1,KCND1,KCNN2,MAT2A,MATN2,KITLG,ADAM22,ZNF92,MXI1,NEK1,NFE2L2,CNOT4,NUCB2,PCSK5,PDE3A,PFKFB2,MTRF1L,PPARA,PPM1B,EPDR1,DCHS2,PTCH1,TMEM260,PTPRD,PTPRE,ZNF844,CEP97,ACSS3,FAM66C,FIGN,SETD5,CCDC25,TCP11L1,TNFRSF19,CASC3,FHOD3,NUBPL,DHX30,ZNF430,TET1,ANKRD36,SNCA,KIF13A,PDZD2,SOX3,MCF2L2,NFASC,CLSTN2,NUDT10,ADGRL3,TBCEL,ATMIN,ZEB1,OBSL1,CYB561A3,SIRT1,DICER1-AS1,ASXL3,TPM1,TSN,ZNF709,XPO1,PCDH20,CELF4,ADAMTS9,PARP11,UBE3B,JMJD1C,RSPRY1" MicroRNA hsa-let-7c*:mirSVR_highEffct hsa-let-7c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.05E-63 4.50E-59 4.24E-62 3.90E-61 165 959 "RALGAPA1,ACADM,CLK4,GALNT13,SLC24A4,SEMA6A,ALCAM,SRPX,ABCD2,MAP4K3,PHF12,NUMB,RNF182,DPY19L3,BACH1,SEC11C,NRP2,SYNJ1,CALB1,LRBA,TIGD7,MS4A7,CNOT8,PPT2,QKI,SULT4A1,FAM171B,CREM,ARHGEF10,OSBPL3,SOCS5,VAC14-AS1,PHACTR3,KIAA0040,ERC2,PHF14,PUM1,ZSCAN23,KIAA0408,ARHGAP32,ARHGAP24,LONRF1,KIAA0586,GIT2,PITPNC1,ZC3H11A,RHOBTB1,SPOCK3,DMD,NR1D2,CPEB2,HIPK3,FAM13A,PHF20L1,MBNL2,KMT5B,ELN,VPS13B,F5,F8,NSRP1,FCGR1A,FCGR1B,SLC9B2,FGF12,FGF14,SEC23B,DCTN2,UFM1,ZNF605,FYN,ERAP1,DISC1,SESN1,GHR,SPIN1,CBX1,FERMT2,ZHX1,ZIC5,HECTD2,SMAD1,EFHB,MEIS2,MIA2,XRRA1,MN1,ZNF680,ZNF92,NEK1,NF1,SLC11A2,NTRK2,CLDN11,OXTR,RETREG1,PLCL1,JAKMIP1,PURG,LRP12,POU6F1,LRRN3,PRKACB,SNRK,MTMR10,PTPRB,PTPRD,PTPRG,KHDRBS2,UBR7,ZFHX4,ROBO2,ZNF354C,SEMA6D,ATXN7,FNIP1,ZFP2,PEAR1,CASC3,FNDC3A,SEC31A,EPN2,DHX30,BTBD7,TET1,MYO16,SP2,CLASP2,SAMSN1,ERBIN,ELOVL4,PLCB1,KLHL4,PCDHB15,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEK,SLC44A1,BHLHB9,R3HDM1,NPL,HIRA,ZNF610,CCDC14,CLDND1,NPDC1,RICTOR,SMARCAD1,GDPD5,PRDM10,VPS35L,FAM13C,AMN1,UBE3B,KAT6A,PHTF2,IFT88,SOCS4" MicroRNA hsa-miR-203a-3p.2:TargetScan hsa-miR-203a-3p.2 TargetScan 8.79E-63 4.92E-59 4.62E-62 4.26E-61 149 782 "NDRG3,BRAP,KIAA1211,PCDH19,KCTD16,OSBPL1A,OSBPL8,PCDH10,AMPD3,PHF12,APBB2,APC,CASK,ARNTL,CDK13,PDE8B,MARCH3,INSYN2B,ADAM23,MPDZ,BCL7A,DST,LDLRAD4,CA12,CABP7,RUNX1T1,KRIT1,CDH2,NUMBL,NRXN3,PLAA,CLTC,C4orf33,HECTD1,CNTFR,NRG2,CLOCK,RBM39,ANKRD44,NCOR1,PLXNA4,APPL1,PNPLA8,PUM1,MATR3,DGKB,DNAL1,NR1D2,DNM1L,EBF1,EDNRA,HEYL,FSD1L,FAM13A,MBNL2,EGR3,RGS17,GPHN,NCALD,ETV1,MRVI1,ANKFY1,AFF2,NBEA,ATP2C1,NSG1,MSANTD4,FYN,MEGF11,GALNT15,GABRB3,GATM,PCDH17,GPR75,GNG4,PTPRT,PADI2,NXPH3,NCKAP1L,NEGR1,MSL1,NKD1,KCNB1,KCNN3,KCNQ3,KIF2A,CYP27C1,LAMP2,LIFR,GPR155,MBNL1,MEF2C,MGAT3,PPM1L,MMP16,SAMD5,NRBP2,HS6ST3,MXI1,MYO5A,NFYA,NOVA1,PCDH8,PCDH9,PDE4D,GPR85,GNG2,PIK3C2A,EPB41L4B,PKIA,PRKCB,MAPK9,MAPK10,PTCH1,EML5,PTPRG,RASGRF1,ERI2,GTDC1,PBRM1,ROBO1,ROBO2,CCDC112,AP1AR,CHD9,FBXO11,ABLIM3,DHX30,CCDC88A,BTBD7,CPEB4,MBD5,FAM126B,NMNAT2,CLSTN2,ADAMTS17,CAMTA1,FAM208A,KIAA0930,RPGRIP1L,DICER1,CBX5,KAT6B,FAM155A,FLRT2,MICU3,KAT6A,JMJD1C,GAN" MicroRNA hsa-miR-505:mirSVR_highEffct hsa-miR-505:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.88E-63 5.53E-59 5.19E-62 4.78E-61 168 995 "CLK4,KLHL32,PLEKHH1,PWWP2A,ESYT2,WDR35,C1QTNF3,SPARCL1,FAM135A,DPP10,LCORL,BCAS1,PLA2G4C,SLC2A11,ADGRB3,MPDZ,SCAPER,VXN,CH25H,USP6,C1orf52,CDH2,LRRFIP1,MAGI1,TIGD7,SRSF11,CHGB,CLTB,QKI,AKAP6,MAGED1,MYRIP,HINFP,TRIM69,SIPA1L1,VCAN,DZIP3,CTH,DOCK4,KIAA0319,DDX46,SPOCK3,MED12,SLC29A4,CPEB2,DPYSL2,PDCD6IP,ABCC5,E2F5,WDPCP,FCF1,TMTC1,FSD1L,PHF20L1,KMT5B,EGR3,RCAN2,FER,POLR1B,PRKAG2,FAM49B,TPK1,CELF1,MSANTD4,OGA,GABRA3,GABRG1,GABRG2,MTHFD2,DISC1,KIAA1841,PPARGC1A,GLYR1,GPR75,TNRC6A,ZNF638,FUT10,GRIA2,CLASRP,AP4S1,PSIP1,ADAMTS6,TOX2,HLF,C2orf72,LRRCC1,KIT,LIMS1,HECTD2,NCOA7,ZNF667-AS1,LRP1B,MEIS1,MEIS2,KCTD6,AFDN,MYCN,MYO9A,HNRNPM,NDP,VWA2,NOVA1,DNHD1,NUCB2,PDCD2,PMP22,LRP12,SCHIP1,MBOAT7,EPB41L4B,MINDY2,EPDR1,MAPK9,HYDIN,VPS13C,BDNF-AS,PTK2,PTN,PTPRO,SH3TC2,RET,SLC25A36,RNASEL,ZFHX4,SETD5,ARMH4,FAM192A,LRFN5,SCN8A,SCP2,KIF21A,HKDC1,ANKRD6,EPN2,CPEB4,ANKRD36,SNAP25,CMTR2,SNRPN,SP4,KDM4C,CLASP2,DIP2A,SEPT3,KLHL7,NAT16,PCDHB3,PUM2,USP32P1,ERCC6L2,TMPO,TPM1,ZNF346,PPIL6,ZKSCAN5,UBTF,WIPF1,ZNF781,PCDH20,ZBTB14,KCNT2,MKRN3,ZNF138,ZSCAN26,ZXDA,PRDM10,UBE3B,GAN" MicroRNA hsa-miR-218:PITA hsa-miR-218:PITA_TOP PITA 1.39E-62 7.80E-59 7.31E-62 6.73E-61 121 506 "ASIC1,ACTN1,TMEM132B,GALNT13,USP31,SLC24A4,CASKIN1,SEMA6A,SYT13,TRMT9B,LCORL,PKP4,RGS20,NUMB,DPY19L3,ADGRB3,SYNJ1,CACNA1I,LDLRAD4,KALRN,DCLK1,FOXN3,SOCS6,NRXN3,SLC35F1,HAPLN1,LRIG1,RIMS4,ERC2,PUM1,GAPVD1,AIF1L,DBN1,ELMO1,RHOBTB1,SPOCK3,HS3ST2,FAM13A,MBNL2,GOLGA7,PAN3,MRVI1,NRN1,MED12L,STAU2,FUT9,GABRB3,PPARGC1A,TOX3,GNAO1,PCLO,GRIA2,PTPRT,RNF165,MIER3,HLF,ELOVL5,ZIC5,KIF2A,LIFR,MBNL1,LRP1B,MITF,HS6ST3,NFIX,GPR137C,PCDH8,ZDHHC8,SERPINI1,PIK3C2A,PIK3R1,TRHDE,MINDY2,PPP2R2C,KANSL1,DIRAS2,RELN,RAP1GDS1,RET,ROBO1,ROBO2,KCNIP3,ATXN2,SCN2B,SMPD3,SEC14L1,SHC4,FHOD3,ABLIM3,WDR47,CCDC88A,SLC12A2,MYO16,SOX11,LMO3,ZC4H2,NKAIN2,STXBP1,NUDT10,SYPL1,TACC1,TCF4,SATB2,TCF12,SYNE1,DOCK9,PUM2,CHST8,RIMBP2,UBE2H,UGT8,TRIM9,CADM2,GDPD5,RNF103,NAV3,PDSS2,RTN4,HNRNPA3,DPF3,GAN" MicroRNA hsa-miR-761:mirSVR_highEffct hsa-miR-761:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-62 7.88E-59 7.39E-62 6.80E-61 161 917 "KCNH8,SYS1,KLHL32,BRAP,PWWP2A,RNF150,ADRA1D,AP2A2,INTS2,C1QTNF3,SPOP,FAM135A,PPP4R4,RGS9,IL33,DDR1,LURAP1,CALB2,THSD7A,PTBP2,LRRFIP1,DLGAP1,SRSF11,RAB33A,PPT2,QKI,FAM149A,AKAP6,COL4A5,TBPL1,ENTPD4,CS,SEC24C,LRRC3B,SOCS5,PHACTR3,PUM1,DCAF4,HDAC9,RIPOR2,KCTD8,DGKG,GIT2,JAKMIP2,MYEF2,C2CD2L,LYPD1,SV2B,DMPK,ABCC5,E2F6,EBF1,SEMA3D,YAF2,PHF20L1,ING4,F8,CLVS1,TAOK3,KAT8,FGF1,FGF14,FHL1,IP6K2,SYNCRIP,NELFCD,TMEM107,FAM49B,CAMKK2,ATP2C1,ZNF274,SULT1C4,GPR162,SESN1,AHDC1,USP19,LYVE1,DHRS4,KCNMB4,GNAL,ZNF782,TDRKH,PCLO,BTN2A1,FAM19A2,RNF165,COQ10A,RNFT2,SLC2A6,MAN1B1,SHISA6,MSL1,IGF1,ZIC5,KCNB1,KCNN1,KIF5A,MAP6,MITF,NINJ2,NNAT,VWA2,NOVA1,NUCB2,IGSF11,LOC100128398,PDE4A,GPR85,ABCB1,SEPT4,PPM1B,QRICH1,BDNF-AS,PTH1R,TMEM260,PPP2R3C,PID1,TMEM255A,RAD51D,OXR1,MRPS18A,RNASE1,SPIN3,STK32B,SALL1,ATXN7,PRCD,TRA2B,CNKSR2,ABLIM3,EPN2,DHX30,KDM4D,SLC8A1,SLC11A1,CPEB4,IFT122,ANKRD36,RBM34,DBNDD2,RGL1,NSFL1C,COBL,MMS19,KIAA1107,DMXL2,TPCN2,DOCK9,SIK3,TEK,TIAM1,FAM155A,UGT8,PCDH20,ANKS1B,SPIRE1,DHX33,PRDM10,PPP1R3F,PLSCR4,GAN" MicroRNA hsa-miR-4273:mirSVR_highEffct hsa-miR-4273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-62 1.04E-58 9.75E-62 8.98E-61 178 1118 "FMNL2,ADCY8,BEND6,MTUS1,KLHL13,AGT,OSBPL1A,CC2D2A,OGT,DPP10,PKP4,USP37,CDK10,EIF4G3,STX16,N4BP2L1,TTLL9,BACH1,MPDZ,CALM1,CAST,MTMR7,SEPT7,LARGE1,NOG,CHN2,SLIT2,PPT2,QKI,CNR1,ARMC8,AKAP6,CNRIP1,CDC42BPB,RBM39,AKAP12,HAPLN1,GDA,SNCAIP,ERC2,PHF14,BOC,GPRASP1,MATR3,KIAA0586,GIT2,FBXL5,LYPD1,SPOCK3,SGSM2,DMD,USP3,DPH1,ECM2,EDN1,HIPK3,FAM13A,CALCRL,EPHB1,ENPP6,GPHN,F5,CLVS1,RPS6KC1,ACSL4,PRMT5,GORAB,IQCG,ANKFY1,NOP56,NELFCD,HVCN1,PDLIM5,STAMBP,MSANTD4,AP4B1,SDCBP2,ZMAT1,KIAA1841,NEU3,TUBGCP4,PCDH17,RAB30,TNRC6A,CCDC184,MCHR1,STMN2,GRB10,DIDO1,PLCD4,CIT,PSIP1,MAP4K5,MIER3,GABARAPL2,HNMT,NEGR1,EID2B,LRRCC1,ITPKB,KCNN3,STMN1,NCOA7,MAP4,MATN3,MBP,MEIS1,MID1,NEFH,SLC11A2,NRCAM,OPA1,GLIPR1L2,PDE1B,PDPK1,PURG,SCHIP1,PPP1R1A,MASP1,CNTLN,BDNF-AS,TMEM260,PTPRN,PPP2R3C,RNASEL,ATP8B4,ATAT1,AP1AR,DGLUCY,SEMA6D,ATXN7,SCN8A,SH3GL3,FUZ,HKDC1,CHD9,SLA,PPP4R3A,FAM214B,SLC12A2,ZFP1,CABCOCO1,SNRPN,SPP1,ATP10B,CLSTN2,POGZ,RGL1,SYNE2,TACR1,CAMTA1,TAL1,MGRN1,TCF12,GPRIN3,PMS2CL,C18orf54,MTMR14,NR2E1,TRPS1,ANKRD20A2,CA14,ZNF610,BCL2L13,VLDLR,WRN,ZNF711,MICU3,MKRN3,CELF4,ZNF225,FAM47E,PDSS2,RGS7BP,FZD3,KAT6A,RNF170,IFT88" MicroRNA hsa-miR-449c*:mirSVR_lowEffct hsa-miR-449c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.93E-62 1.08E-58 1.01E-61 9.31E-61 161 919 "ACADM,CLK4,TMCC3,PLEKHH1,OSBPL1A,AK2,CARNS1,PPFIA3,IGDCC4,SPTBN4,ZFYVE28,PDE8B,ALDH7A1,DPY19L3,BCHE,SYNJ1,CA8,CALB1,CLGN,SOCS6,TPP1,CLTC,ANKRD35,SUMF2,NRG2,GDA,CLIP3,OSBPL3,CSNK1G3,CNTNAP2,KIAA0040,RIMS2,RUBCN,CCDC144A,KIAA0408,HDAC9,ARHGAP32,KATNAL2,RIPOR2,ZNF337,BRINP1,GIT2,KIAA0319,KLHL3,CDON,DTNB,SNX29,FAM13A,EGR3,RASA4,PAN3,ENPP6,NCALD,MRPL37,MRVI1,TAOK3,SUCO,SEC23B,SYNCRIP,PDLIM5,NSG1,KIAA1841,GCNT2,CYP46A1,MSL3,GLUL,ADGRA3,GPR34,TMEM121B,FRMD5,HLF,GABARAPL2,DHX35,LRRC75A,IFI16,IL6ST,LAMP2,GPR155,MAT2A,MATN2,SRSF12,KCTD6,SCAMP5,MITF,AFF1,NCF2,NEK1,TBC1D25,CNTN3,PFKFB2,PIK3C2A,PRIMPOL,LRP12,PPARA,DEF8,NCR3LG1,ZSCAN32,PTPRG,PTX3,RIPOR1,TUG1,TMEM231,FAM66C,ZNF793,FAT4,RAP1GDS1,TRIM68,RNASEL,ALG9,ROBO2,MRAP2,BAALC,ZNF671,ADAL,CLIP1,ATXN2,SCP2,KIF27,ZFP30,FERMT1,SLC9A5,SLC14A1,GKAP1,USP33,DOP1A,ITPRID2,SEPT8,DIP2A,SULF2,PRRC2C,NUDT10,PLCB1,SYT1,TACR1,EXOC7,PDLIM2,TBCEL,TCF12,OBSL1,USP32P1,DICER1,NPL,C9orf85,SYNPO2,TRIO,PPIL6,ANKRD20A2,FLRT2,CELF4,DPYSL5,CADM2,EVI5,ADAMTS9,GAL3ST3,URM1,EPM2A,DOCK8,KAT6A,PHTF2,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-4314:mirSVR_highEffct hsa-miR-4314:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.27E-62 1.27E-58 1.19E-61 1.10E-60 170 1024 "ABCF1,KCNH8,ASIC1,FMNL2,BRAP,ADGRF5,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,APAF1,APLP1,TNRC6C,USP37,SEMA4G,PPP4R4,ARRB1,ATP6V1G2,SEC11C,CFLAR,SYNJ2,CAST,USP6,CHN2,NDST3,PPT2,CLTC,FBXO7,MAP4K4,ARHGEF6,ARMC8,ANKRD44,CLIP3,TRIM69,CS,CSF2RA,APPL1,UBXN2A,GREB1,RUBCN,BOC,HDAC9,GAPVD1,RIPOR2,DCAF8,TMEM170A,ARMCX4,HEPH,FBXL5,DMD,CDON,DTNA,EDN3,PHF20L1,EGR3,STX2,SRRM1,CDKL3,VPS26C,SIRPB1,RPS6KC1,CEP78,FER,FGF1,FGF11,FGFR1,FLT1,NOP56,PRELID3A,STAU2,HRASLS5,GABRG2,GALC,RAPGEF6,KIAA1841,IGSF5,GCK,WASHC2A,TOX3,GPD2,GRIK5,PRDM5,ZNF496,COQ10A,AP4S1,GUCY1B1,HAS2,FRMD5,VSIG4,SMAP1,MYLK2,KCND1,IPO5,HECTD2,MAT2A,POC1B,MT1M,RTL5,NF1,NRCAM,NTRK3,NUCB2,OPA1,PALM,PCSK1,PRTG,PIK3C2A,SMIM7,PURG,SCHIP1,SEPT4,GRAMD1C,VPS13C,APTX,WDR25,CNTLN,OXR1,GAL3ST4,RGS12,RNASEL,EXD2,KIRREL1,RPE,FBXW7,ATP8B4,ABCA11P,NCBP3,SAFB,CASC3,KIF27,SH3BGR,FRMPD1,MYO18A,SHMT2,HKDC1,NLGN1,WDR47,SLC6A11,CCDC88A,SLC22A4,RCOR3,ZSWIM8,SP4,LHPP,ELOVL4,SULF2,SYN1,SYN2,DNMBP,PCDHB7,C18orf54,ITGB3BP,ENHO,ERCC6L2,PRRT1,C9orf85,TRO,RUSC1,CA14,CCDC14,VLDLR,ZNF70,ZNF138,CELF4,PRTFDC1,DNALI1,HPS4,PARP11,FAM13C,SMIM8,IFT88,AP3B2" MicroRNA hsa-miR-670:mirSVR_highEffct hsa-miR-670:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.52E-62 1.41E-58 1.31E-61 1.21E-60 166 978 "CLK4,ADD1,PTCHD1,BEND6,AP2A2,CEP126,CARNS1,PKP4,APC,BCAS1,TTLL9,SEC11C,CFLAR,ARHGEF7,SCAPER,GYG2,CALB2,ARHGEF2,ZBED1,CHN2,NDST3,C4orf33,QKI,LY86,ARMC8,SUMF2,CNRIP1,C2CD2,CREM,NCOR1,GDA,PHACTR3,CCDC144A,ZFYVE16,ZNF337,DGKB,TMCC2,NR1D2,RCAN1,ARRDC4,ABCC5,EBF1,EDN1,FCF1,PHF20L1,TMEM132E,PLEKHA1,MRNIP,EPHB1,CDKL3,CLVS1,SCML2,CORO2B,FCGR1A,FER,FGF14,SEMA4D,STAU2,CHL1,ACSS1,KIAA1841,SULT1C4,GPR162,RAB30,ZNF638,GNAL,GNG4,WDFY3-AS2,GPD2,FUT10,GPR12,LPAR4,GRB10,BTN2A1,ZBTB49,FAM107A,ZHX1,AGBL5,HNF4G,HNMT,NEGR1,NME9,KCNN2,LIMS1,MARK1,MBD1,MEF2C,ZNF680,ZNF92,MYT1,NCAM2,NF1,DNHD1,OPA1,PIK3C2A,PKM,EXOSC10,SEPT4,DRAM2,GRAMD1C,BCAS3,CNTLN,TMEM260,STK32A,ZIK1,PTPRE,CEP97,FAT4,ZNF493,UBR7,TMLHE,CARF,GSTCD,ADAL,ABCA11P,SEMA6D,ATXN7,COPZ1,FRMPD1,PPP4R3A,SLC9A5,SLC22A4,RCOR3,ANKRD36,SNCA,CMTR2,SNRPN,KDM4C,CDK19,ZC4H2,SS18,ZSCAN29,ELOVL4,SEPT8,ARHGEF9,PLCB1,TBCEL,ZFP90,RPGRIP1L,SYNE1,SLC44A1,TLR4,NR2E1,PIK3R5,NPL,RGMB,ZKSCAN5,FAM155A,ZFP37,ZIC1,ZNF708,ZNF19,ZNF24,TRIM9,ZNF177,FSTL5,SPIRE1,MAP3K12,EMSY,ST7,MARCH8,UBE3B,HNRNPA3,RNF170,IFT88,FAM198A" MicroRNA "TTTGCAC,MIR-19B:MSigDB" "TTTGCAC,MIR-19B:MSigDB" MSigDB 3.78E-62 2.12E-58 1.97E-61 1.82E-60 118 483 "ABR,ACTN1,SLC24A4,HECW2,PCDH10,PITPNM2,OGT,LRCH2,CDK13,ZBTB10,ATP2B2,NRP2,ST3GAL5,CALM1,CAST,PRC1,USP6,SEPT7,EVI5L,PLAA,CLTC,QKI,CNTFR,ARMC8,SLC35F1,CLOCK,GDA,CS,LRIG1,SOCS5,PPP6R2,SNPH,HDAC4,LONRF1,DBN1,SPATA2,WDR20,ARRDC4,MBNL2,PLXNC1,EMX2,ERBB4,NCALD,ETV1,ACSL4,PTK2B,DLC1,MED12L,OLFM1,FOXF2,FLNC,NBEA,ATP2C1,ARFIP1,TNRC6A,CBX1,RNF165,SOX21,HLF,ELOVL5,IGF1,KIT,MBNL1,AFF1,MYCN,CNOT4,OCRL,PFKFB3,CCSER2,PPARA,PPP2R5E,PSD,WBP1L,PTPRG,RBBP8,ROBO2,RTN1,RXRA,SGK1,FNDC3A,SYBU,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,BTBD7,CPEB4,USP33,CDK19,SPART,RGL1,PRRC2C,PLCB1,ARC,SYT1,ANKRD12,CAMTA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,CSMD1,WBP2,TRPS1,TSC1,USP32P2,SPHK2,DPYSL5,SPIRE1,MAP3K12,NAV3,PHTF2" MicroRNA "TTTGCAC,MIR-19A:MSigDB" "TTTGCAC,MIR-19A:MSigDB" MSigDB 3.78E-62 2.12E-58 1.97E-61 1.82E-60 118 483 "ABR,ACTN1,SLC24A4,HECW2,PCDH10,PITPNM2,OGT,LRCH2,CDK13,ZBTB10,ATP2B2,NRP2,ST3GAL5,CALM1,CAST,PRC1,USP6,SEPT7,EVI5L,PLAA,CLTC,QKI,CNTFR,ARMC8,SLC35F1,CLOCK,GDA,CS,LRIG1,SOCS5,PPP6R2,SNPH,HDAC4,LONRF1,DBN1,SPATA2,WDR20,ARRDC4,MBNL2,PLXNC1,EMX2,ERBB4,NCALD,ETV1,ACSL4,PTK2B,DLC1,MED12L,OLFM1,FOXF2,FLNC,NBEA,ATP2C1,ARFIP1,TNRC6A,CBX1,RNF165,SOX21,HLF,ELOVL5,IGF1,KIT,MBNL1,AFF1,MYCN,CNOT4,OCRL,PFKFB3,CCSER2,PPARA,PPP2R5E,PSD,WBP1L,PTPRG,RBBP8,ROBO2,RTN1,RXRA,SGK1,FNDC3A,SYBU,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,BTBD7,CPEB4,USP33,CDK19,SPART,RGL1,PRRC2C,PLCB1,ARC,SYT1,ANKRD12,CAMTA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,CSMD1,WBP2,TRPS1,TSC1,USP32P2,SPHK2,DPYSL5,SPIRE1,MAP3K12,NAV3,PHTF2" MicroRNA hsa-miR-1285:mirSVR_highEffct hsa-miR-1285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.91E-62 2.75E-58 2.56E-61 2.35E-60 158 891 "ADCY6,ADORA2A,TAOK1,PCDH10,FAM135A,DPP10,SUGT1P4-STRA6LP-CCDC180,VAT1L,STK33,CFLAR,CA4,KALRN,PTBP2,CBS,CLDN10,METTL6,P2RX6,CD86,CD38,SEPT7,CDC25B,ZMYM4,LRRFIP1,TIGD7,COL4A5,GDA,TRIM69,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,DZIP3,PPP1R16B,CTH,CCDC144A,KATNAL2,ARHGAP24,PABPC5,HEPH,ZC3H11A,DDX46,SV2B,SGSM2,EXOG,DPYSL2,ABCC5,SNX29,RASGRP1,KLHL5,FAM13A,EGR3,CERCAM,SRRM1,ZNF549,FAM198B,CEP78,KAT8,SLC9B2,FGF1,SPSB4,FGFR1,FLT1,NOP56,TRIM16,STAU2,GABRA3,B4GALNT1,ZNF274,GCNT2,SRCAP,ZNF276,COPS8,KDM2B,MAP7D2,POLL,MIER3,ZIC5,IL6ST,KCNB1,GPR62,KHK,PAXBP1,NCOA7,PIK3AP1,MBNL1,MEF2C,MMP16,ZNF92,MYO7A,SFR1,NEFH,NFE2L2,VWA2,NTRK3,IGSF11,CLDN11,PKM,PLCL1,SEPT4,SH3KBP1,PPP1R1A,PPP2R2B,GDPD2,ZSCAN32,EML5,PPP2R3C,MARCH1,OXR1,RET,RGS4,RIC8B,ROBO1,ELP2,ATAT1,ZNF568,RMI1,ATXN7,SCN8A,TNFRSF19,SEC14L1,COPZ1,CHD9,R3HDM2,ANKRD6,SEPHS1,ATF7IP,SNCA,CMTR2,SNRPN,SPTAN1,LMO3,SS18,SULF2,SEPT3,NSFL1C,JMJD6,DMXL2,SATB2,TCF12,GPRIN3,PMS2CL,ITGB3BP,ZMAT3,ERCC6L2,PPIL6,UBE2H,WIPF1,ZBTB14,ZNF711,MICU3,TRIM9,NDRG4,REEP1,SMARCAD1,EMSY,PRDM10,KAT6A,FRMD6" MicroRNA hsa-miR-3115:mirSVR_lowEffct hsa-miR-3115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.02E-62 2.81E-58 2.62E-61 2.41E-60 165 971 "ACADM,SYS1,GALNT16,PSMG3-AS1,ADD2,ADRA1D,BEND6,ZNF608,HACE1,CC2D2A,ALCAM,BBOX1,PARG,LGR5,MADD,TMEFF1,CADPS,NUMB,SLC4A4,ATP1B3,RNF182,JAZF1,CA12,CACNA1B,CAMK2G,ISPD,DGKI,LARGE1,SRSF11,NDST3,CNR1,SLC4A8,TBPL1,MYRIP,SNCAIP,CSF1,DZIP3,CTH,BOC,KIF26A,DAPK1,BRINP1,SPOCK3,WDR20,WDPCP,HIPK3,TMTC1,MBNL2,KMT5B,GOLGA7,EIF1,VPS13B,RCAN2,GPHN,PIPOX,CLVS1,SCML2,CHST15,FGFR1,SUCO,IP6K2,NOP56,GABRB3,ERAP1,CYP46A1,SPIN1,RAB30,GRIA2,ARHGAP36,HMGCL,TCEAL6,SMAP1,SOWAHA,IL6R,KCNN3,STXBP5,MATN2,MBNL1,MBP,KITLG,PPM1L,POC1B,AFDN,ZNF680,COL28A1,ADAM22,MYO9A,CNOT4,NPY,NOVA1,NLGN3,SNX10,RETREG1,XRN1,MTRF1L,ING3,CEP41,MAPK10,CNNM2,NCR3LG1,PTPRE,PTPRH,CCDC40,GTDC1,PRIMA1,KLHL11,SLC25A36,CCDC82,PNMA8A,GSTCD,SNX22,ATAT1,ZNF568,FAM192A,FNIP1,KIF27,CHD9,SYBU,WDR37,ABLIM3,PPP4R3A,SLC9A5,SLC14A1,ATF7IP,DOP1A,TRERF1,BDP1,DOK5,HECW1,UHRF1BP1L,PEG10,IQSEC2,RBM26,NKAIN2,ZSCAN29,RGL1,KLHL7,SLC19A3,PCDHB7,PCDHB6,C18orf54,AKTIP,TIAM1,TLR4,TMPO,TRPS1,TTTY15,ZKSCAN5,CLHC1,CLEC2L,VIPR2,TBC1D15,ZIC2,ZNF74,CELF4,REEP1,TMEM237,FTSJ1,EMSY,HPS4,CIAPIN1,FAM47E,FAM13C,SNX14,NETO2" MicroRNA hsa-miR-200b*:mirSVR_highEffct hsa-miR-200b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.35E-62 5.23E-58 4.86E-61 4.48E-60 163 952 "XKR4,NDRG3,BRAP,KLHL13,KCTD16,RTL9,NME5,ADGRF5,OGT,MAP4K3,CDK13,SLC2A11,BMPR1B,KALRN,CAST,CCK,CNOT8,TPP1,QKI,CNR1,RCHY1,SLC35F1,FAM171B,HAPLN1,SEC24C,IPCEF1,SLITRK5,PITPNM3,ERC2,PHF14,CTH,TCAF1,ZFYVE16,ARMCX4,PITPNC1,TIAM2,DDX46,PLPPR4,DPP6,PDCD6IP,E2F6,EDNRA,FRY,FAM13A,GPHN,STX2,MRPL10,DNAJC27,F5,CLVS1,DLC1,MED12L,FGF13,FGFR3,UFM1,ERGIC3,ST6GALNAC3,CHL1,DISC1,IGSF5,SULT1C4,MSTN,ARFIP1,COPS8,GLUL,KDM2B,PRUNE2,ATP2B1-AS1,ZHX1,MIER3,SHISA6,EID2B,RBPJ,KCND2,KCNJ16,CREG2,STMN1,PIK3AP1,MAP4,MBD1,MBNL1,MEIS2,POC1B,ZNF680,MSR1,ZNF92,NCF2,NEK1,NOVA1,SLC11A2,SMIM11A,NTRK2,PDE3A,GPR85,GNG2,NLGN3,SERPINI1,PIK3C2A,ZNF655,ING3,POLR2F,PRKAB2,EPDR1,TMEM260,ZSCAN32,PEX2,ZNF493,SLC25A36,NUDT11,CARF,GSTCD,PCMTD2,CCDC102B,RPE,ATP8B4,CSRNP3,SGK1,SH3GL3,ZNF430,BTBD7,SLC22A4,TTC17,LIMCH1,SNRPN,GLT8D1,KDM4C,SSTR2,ZSCAN29,NEK4,DIP2A,ARC,DNMBP,FAM208A,TCEA1,TCF4,USP22,PCDHB6,FRYL,DICER1,SIRT1,ZFPM2,BHLHB9,TMPO,EIF4ENIF1,UBE3A,MTCH1,WRN,CLDND1,XRCC4,ZNF708,KCNT2,ZNF138,SMARCAD1,STOX2,PRDM10,RGS7BP,AMN1,FZD3,PHTF2,ADAMTSL3,NHSL1,FRMD6,GAN" MicroRNA hsa-miR-196a*:mirSVR_highEffct hsa-miR-196a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-61 6.81E-58 6.32E-61 5.82E-60 159 908 "RALGAPA1,NDRG2,ADCY6,ADD1,RNF150,RTL9,HACE1,OSBPL1A,CC2D2A,PDZD4,ANK2,PKP4,APC,ZBTB10,DPY19L3,NRP2,JAZF1,AP1M1,CA8,CACNB4,KALRN,DCLK1,ZMYM4,MAGI1,CFL2,SOCS6,HECTD1,CNTFR,AKAP6,ABI3BP,IGDCC3,FAM171B,PREPL,HAPLN1,AATK,RIMS2,USP6NL,HDAC9,RHOBTB1,PLPPR4,KIF19,DYNC1I1,DNAJB6,KRBA2,HIPK3,FCF1,FSD1L,PHF20L1,SUGP2,EGR3,EIF4G2,C8orf37,DCTN4,LRRC17,SRRM1,NCALD,FAM198B,PPP1R1B,FHL1,FOXF2,IP6K2,SYNCRIP,FOXO3,SLC37A3,C2orf88,TPK1,STAU2,AP4B1,GPR162,BRD8,TCERG1,TNRC6A,TDRKH,GPR12,PCLO,ADAMTS13,PADI2,ELOVL5,HNMT,IRF8,ZNF678,KCNJ16,KIF5A,KIT,CYP27C1,PACRG,PIK3AP1,GPR155,ZNF667-AS1,MEIS2,NDP,NF1,NRCAM,ENPP2,GPR85,NALCN,SMIM7,PPM1B,PPP2R5E,EPDR1,RASGRF2,MSANTD2,CRTAC1,PRRT2,ERI2,FIGN,RGS12,SLC25A36,PBRM1,CARF,ELP2,PCMTD2,ARMH4,ATAT1,KCNIP1,ZNF354C,ZNF331,SCP2,FNIP1,FAM102A,CHD9,SEC31A,FAM81A,CCDC88A,NAPB,TET1,ZFP1,SNCA,TEX2,ST5,SEPT8,TTBK2,DIP2A,SYP,SYPL1,AGTPBP1,ATMIN,ZEB1,TCF12,NACC2,CSMD1,TRIO,RUNDC3B,TSN,ANKRD20A2,TSC1,UBE3A,PLEKHH2,LAT2,ZBTB14,KCNT2,TCEAL7,REEP1,SPIRE1,TMEM178A,AMN1,JMJD1C,NLRP3,MSRB3" MicroRNA hsa-miR-369-3p:TargetScan hsa-miR-369-3p TargetScan 1.22E-61 6.83E-58 6.34E-61 5.84E-60 115 461 "ABR,ADCY5,ESYT2,AP2A1,PCDH19,ARHGAP20,PCDH10,FAM135A,LRCH2,APBB2,GAS7,PDE8B,DST,LDLRAD4,CDH2,DCLK1,NOG,NUMBL,CFL2,CNOT8,QKI,HECTD1,NRG2,HAPLN1,ABCG1,PHACTR3,PLXNA4,GIT2,PITPNC1,MFAP3L,KLHL3,FAM107B,DMD,RCAN1,EBF1,SEMA3D,MBNL2,PLXNC1,EPB41,DENND4A,CEP85L,EYA1,MED12L,FLT1,APOPT1,FYN,CHL1,GABRB3,GFRA2,FREM1,FAM19A2,RASSF8,HLF,NKD1,RBPJ,CDH20,KCNN3,KTN1,LSAMP,MAP2,MBNL1,LRP1B,MEIS1,MGAT3,AFF1,MMP16,MYO9A,NF1,NFIX,NPTX1,NPTX2,OCRL,OPA1,P2RY1,PAX6,PDE3A,PDE4A,PDE4D,PDPK1,FAM216A,PURG,PPP2R2C,PRKAB2,CEP41,PKIA,PTPRG,OXR1,PRIMA1,RORB,HUNK,SATB1,CSRNP3,SCN2B,FNIP1,ARHGEF40,MBD5,IQSEC2,CDK19,NKAIN2,PRRC2C,ATMIN,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DOK6,RBFOX3,KCNK12,PPP1R3F,RGS7BP,JMJD1C" MicroRNA hsa-miR-182*:mirSVR_lowEffct hsa-miR-182*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-61 7.05E-58 6.53E-61 6.01E-60 182 1181 "CLK4,EMILIN3,GALNT13,BEND6,MTUS1,HFM1,SEMA6A,PCDH10,OGT,PKP4,MADD,MARCH3,TMEM108,RNF182,RIPK1,ADAM23,BCHE,DNAJC27-AS1,ARHGEF7,CA8,KALRN,CH25H,CD86,PLAA,CLTC,FAM19A5,CNN3,CNR1,IQCK,PCYT1B,FAM149A,CABP1,ZNF385A,PREPL,RBM39,RNF14,ABCG1,SNCAIP,CSF1R,CSF2RA,ARHGEF10,IPCEF1,PLXNA4,PLCXD3,ZSCAN23,CCDC144A,MYADM,ARHGAP24,AIF1L,DNAL1,YTHDC1,MYEF2,KIAA0319,SPOCK3,MTX3,DMTF1,CASP8AP2,DNAJB6,SNX29,FRY,EGFR,EIF4G2,TENM1,MRNIP,ACSL4,FER,FGF1,FGF12,TMEM164,SEC23B,SYNCRIP,FOXO3,ATP13A4,FLT1,PSD2,NBEA,UFM1,CELF1,GABRG2,GAD1,FAM120B,DISC1,ACSS1,LRRC37A6P,KIAA1841,HPGDS,LUZP2,GPD2,LPAR4,GPR37,PCLO,BVES,PSIP1,UBE2QL1,PADI2,ZHX1,MIER3,GABARAPL2,SHISA6,EID2B,MSL1,ZIC5,INSM1,KCNJ16,LAMP2,PPM1L,XRRA1,SAMD5,BLOC1S2,MSR1,TCEAL5,SMIM11A,PCSK1,PDPK1,PIK3C2A,JAKMIP1,SCHIP1,EPB41L4B,PRKACB,SAMD9,PIGG,CNTLN,PTK2,SPDL1,PTPRB,PID1,ZNF793,FAM184A,RASGRF1,RBBP6,ERI2,RFX3,SLC25A36,ROBO2,NEK11,LRRK2,ZNF354C,SEMA6D,SBF1,ATXN7,SCP2,KIF27,SH3BGR,AMBRA1,PPP4R3A,ANKRD36,CMTR2,SOX3,ZC3H13,RBM26,ZSCAN29,KLHL7,COBL,C12orf76,TBCEL,FBXW11,ZEB1,TRIM2,NAT16,FRYL,HIF3A,PIK3R5,TPM1,C9orf85,STXBP4,USP1,TBC1D15,CLDND1,MICU3,NDRG4,LYPD6,ZNF142,ANKS1B,SLC38A1,STOX2,HPS4,SEMA3B,MDH1B,ITM2C,PDSS2,SNX14,DPF3" MicroRNA hsa-miR-202*:mirSVR_lowEffct hsa-miR-202*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-61 7.24E-58 6.70E-61 6.17E-60 199 1397 "SYN3,XKR4,GALNT16,PWWP2A,PTCHD1,MTUS1,WDR35,ZNF578,SPARCL1,ALCAM,CEP126,ARHGAP20,FAM135A,DPP10,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,PPP4R4,IGDCC4,ARNTL,STK33,ZBTB10,SLC4A4,EIF4G3,ATP2A2,ATP6V0A1,BCL7A,FUBP1,JAZF1,RAB29,MYRF,KALRN,ISPD,DLGAP1,CHN2,PPT2,CNN3,AHCTF1,BAG4,SLC35F1,RBM39,HAPLN1,PDE4DIP,CST3,PLXNA4,SLITRK5,USP6NL,CCDC144A,CYBB,GAPVD1,IST1,AIF1L,GIT2,DNAL1,ZBTB24,SNAP91,FAM107B,GRIN3A,RAB39B,DNAJB6,KLHL5,YAF2,PLEKHA1,EPHB1,CEP85L,VPS26C,CORO2B,FHL1,SCARA3,PCYOX1,SYNCRIP,EFCAB2,TMEM107,SMC2,UFM1,TRAF3IP2,ZNF234,DISC1,PPARGC1A,ZNF276,GLI2,TOX3,ZNF782,GNG4,FERMT2,ATOH8,RASSF8,ZHX1,TNFAIP8L3,BACH2,VSIG4,HNMT,SCIN,JAK2,SLC35G1,LIG4,HECTD2,NCOA7,SMAD9,GPR155,MAP2,MAP6,MBP,CHIC1,TM6SF1,MEIS1,MEIS2,MID1,MMP16,ZNF680,ADAM22,P2RY13,ZC3H12B,IDNK,NFYA,CNOT4,NTRK2,NUCB2,OPA1,OXTR,PCSK1,PIK3R1,RETREG1,STRN3,ING3,SH3KBP1,TATDN3,PPP5C,RANBP3L,EPDR1,HYDIN,SPDL1,PTPRB,PTX3,ACSM5,CCDC40,KHDRBS2,RGS3,PRIMA1,ROBO2,ELP2,PCMTD2,EPHA10,BAALC,ATP8B4,LRRK2,ATAT1,ZNF354C,AP1AR,ATXN2,SCP2,GALNT10,ZFP30,CPEB3,SEC31A,SLC2A5,SLC6A8,SLC12A2,TET1,MBD5,SNRPN,TRERF1,NMNAT2,CDK19,CAMTA2,ZSCAN29,ELOVL4,NECAB1,PRRC2C,PLCB1,SYT1,COBL,ANKRD28,C12orf76,TACC1,EXOC7,FAM208A,TRIM2,CLASP1,SYNE1,DOCK9,CRTC1,RNF216P1,TK2,FAM124A,ZNF346,ELP5,STXBP4,SSBP2,EIF4ENIF1,CLIP2,ZNF781,PCDH20,ZNF28,ZNF45,RNF103,MDH1B,PDSS2,FXR1" MicroRNA hsa-miR-3202:mirSVR_highEffct hsa-miR-3202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-61 7.57E-58 7.00E-61 6.45E-60 174 1084 "ABR,ADCY6,OSBPL1A,FAM135A,OGT,PHF12,SUGT1P4-STRA6LP-CCDC180,ZBTB10,STX16,N4BP2L1,ATP6V1G2,PROM1,SYNJ2,SCAPER,WASF1,CACNB4,KALRN,CBLN1,CERS5,SYNGR3,CD38,PLEKHB1,TAOK2,EPS15L1,PPT2,CLTC,ABCG2,QKI,SLC4A8,CPS1,CRMP1,MYADM,ARHGAP24,EARS2,ZNF337,KIAA0586,SPOCK2,SPATA2,B3GAT3,C2CD2L,POM121,KIF19,GRIN3A,DNM1,DNAH9,FAM78B,EDN1,FCF1,CNNM1,ING4,CALCRL,HSD17B14,VPS13B,EPHB1,SPEG,MRPL10,ETV1,RASL12,ZNF461,PTK2B,TAOK3,DLC1,GTF2IRD2,FHL1,STAMBP,USP21,CAMKK2,ATP6V1H,GABBR1,HRASLS5,GGT7,RUNDC3A,GLYR1,RAB30,KDM2B,GP1BB,CCDC184,MCHR1,PLCD4,GRIN2D,KAT7,RABL2A,ATXN2L,ARHGAP36,SYNPO,ITGA7,ITPKA,GPR62,STMN1,MAP4,MBD1,KCTD6,MN1,BLOC1S2,ADAM22,N6AMT1,MXI1,NF1,NNAT,NOVA1,NPR2,NTRK3,NUCB2,PDE4A,PURG,EPB41L4B,MAPK4,EPDR1,KLK6,APTX,CNTLN,PTK2,PTPRD,TRIM68,DPF2,NUDT11,ZNF532,SETD5,CARF,NEK11,ARMH4,ATP8B4,ATAT1,FAM192A,FNIP1,COPZ1,FRMPD1,SHMT2,CHD9,DHX30,WDR47,FAM214B,CCDC88A,ELMO2,SMARCA4,ZC3H13,LMO3,SYN2,ANKRD28,TACC1,MLST8,FBXW11,TCEA1,CUX2,TCF12,CLASP1,USP32P1,THRA,TIAM1,PRRT1,R3HDM1,CSMD1,KAT6B,TPM2,ELP5,KCNE5,TSN,SGK3,SLC35A4,OSBP2,FLRT2,WIPF1,CLDND1,RICTOR,XPO1,ZIC2,EML6,PRDM10,NAV3,FIP1L1,MARCH8,UBE3B,RNF170,KLHDC1" MicroRNA hsa-miR-188-3p:mirSVR_highEffct hsa-miR-188-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-61 9.74E-58 9.00E-61 8.29E-60 170 1038 "KCNH8,AP2A2,KIAA1324,TAOK1,ALCAM,SYT13,OGT,MAGEE2,FAM131A,MARK4,ZSCAN18,SLC4A4,ATP1B3,ZNF583,N4BP2L1,LINC00847,DST,IL33,THSD7A,PTBP2,VXN,DGKI,CDH2,LRRFIP1,MAGI1,SLIT2,RAB26,COL4A5,SUMF2,IGDCC3,AKAP12,SNCAIP,CSF1,PDE4DIP,PHF14,ZFYVE16,KCTD8,PABPC5,DBI,GIT2,ARMCX4,KIAA0319,ALKBH8,CHRDL1,USP3,DMTF1,KLHL5,PHF20L1,TNK2,TMEM35A,CALCRL,LRRC17,CDKL3,NRN1,CLVS1,SLC9B2,FER,FGF14,SUCO,SYNCRIP,FLT1,PSD2,UFM1,ZNF44,ZNF559,DISC1,ADAM28,GFRA2,RAB30,ZNF782,PCLO,GRIA2,DIDO1,PSIP1,HAS2,ARHGAP36,ELOVL5,MSL1,ZNF181,ZNF546,RBPJ,KCNN1,KIT,STXBP5,NCOA7,MBNL1,ZNF680,MT1M,NEXMIF,ZC3H12B,NEK1,NRCAM,OCRL,LOC100128398,CDK18,PDE1C,ABCB1,NALCN,ZNF655,PLCL1,ZNF426,STRN3,IRX1,CCDC144B,PRKACB,DIRAS2,MASP1,PTPRD,PTPRO,C1orf109,ZNF844,ZNF493,RADX,SUGCT,EXD2,CARF,ELP2,CCDC102B,MEG3,KCNIP1,NCBP3,ZNF331,ZFP2,ZFP30,CHD9,SLC6A8,CCDC88A,SLC22A4,ZFP1,CDK5RAP2,RCOR3,KDM4C,TEX2,ZNF302,ZSCAN29,NEK4,ARHGEF9,VPS13A,TAL1,TCEA1,ZFP90,ZEB1,RPGRIP1L,CLASP1,PCDHB6,FRYL,SIK3,DICER1,TMPO,WBP2,METTL3,SSBP2,FAM155A,ZNF781,ZFP37,ZNF711,LYPD6,ZNF138,SLC30A4,PRTFDC1,EVI5,NAV3,PPP1R3F,PDSS2,RGS7BP,DOCK8,RTN4,PHTF2,TRAM2-AS1,ZNF30" MicroRNA hsa-miR-365*:mirSVR_lowEffct hsa-miR-365*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-61 1.12E-57 1.04E-60 9.53E-60 163 957 "ASPHD1,TMEM132B,GALNT13,ADD1,C1QTNF3,USP35,TRMT9B,ZFAT,FGD2,CCDC146,SUGT1P4-STRA6LP-CCDC180,PARG,EPB41L5,APLP1,UPRT,PPP4R4,PLA2G4C,STK33,MARK4,ATP1B3,SLC2A11,KSR1,ARHGEF7,RUNX1T1,CBS,CERS5,ARHGEF1,CBFA2T2,EVI5L,LOC730101,SOCS6,ASIC3,NRXN3,CLCN3,DGCR9,LY86,ARHGEF6,ARMC8,NECTIN3,SLC35F1,RBM39,CRY2,CLIP3,SNCAIP,CSF1R,OSBPL3,IPCEF1,ERC2,PHF14,RUBCN,CCDC144A,GPRASP1,ARHGAP32,ARHGAP24,MAML1,ARMCX4,PITPNC1,RAB39B,CDON,SLC12A6,SLC25A18,DTNA,SUGP2,EGFR,MRO,CALCRL,ZNF549,F8,PTK2B,CORO2B,FHL1,SUCO,ERGIC3,AP4B1,CHL1,GALC,GHDC,SEPT9,LRRC37A6P,CPLX2,SRCAP,PLCD4,BTN2A1,GSTM5,BVES,BACH2,IL6R,ZFYVE27,MAP6,MARK1,MBP,TM6SF1,MEIS1,MID1,MYO9A,ZC3H12B,NFYA,NTRK2,P2RX7,TREM2,PDCD2,OLA1,ZNF655,PSAT1,SDK2,POLR2F,PPM1B,PPP3CA,RASGEF1B,BCAS3,PIGG,ZSCAN2,TTC13,RASGRF1,RFX2,KCTD17,CARF,CYB561D1,FBXW7,GLDN,ABCA11P,SEMA6D,RASA3,ST6GAL1,WDR37,SIRT2,KBTBD4,MAST1,SMARCD3,DOP1A,TRERF1,UHRF1BP1L,KDM4C,UNC5B,PEG10,RBM26,NFASC,APOM,PHLDB1,KIAA1107,FBXW11,KLHL4,MGRN1,ATMIN,SATB2,TRIM2,HIF3A,ITGB3BP,AP4E1,AKTIP,PIK3R5,TPM2,SSBP2,GORASP1,LINC00689,PLPPR2,MKRN3,ZNF213,PRDM10,ADAMTS9,SLC17A7,DOCK8,UBE3B" MicroRNA hsa-miR-301a:PITA hsa-miR-301a:PITA_TOP PITA 2.01E-61 1.13E-57 1.04E-60 9.54E-60 133 633 "ASIC1,CCDC85A,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,STK33,NCOA1,ATP2B2,ADGRB3,NRP2,LDLRAD4,THSD7A,USP6,MAGI1,CFL2,SOCS6,PLAA,CLTC,QKI,CNR1,CLOCK,GDA,LRIG1,SOCS5,APPL1,ARHGEF4,PPP6R2,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,FAM107B,DPYSL2,ABCC5,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,SLC43A2,ERBB4,ACSL4,SCML2,MED12L,FOXF2,NBEA,FUT9,GABRA3,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,GRB10,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KIT,MBNL1,CHIC1,AFF1,MYT1,NPTX1,PDE1C,PDE4B,PFKFB3,PIK3C2A,CCSER2,LRP12,RELN,PSD,MTMR10,PTPRD,PTPRG,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,TEX2,CDK19,TSPYL2,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,TACC1,ANKRD12,CAMTA1,FBXW11,TCF4,SATB2,TRIM2,DICER1,ZFPM2,SLC44A1,RIMBP2,R3HDM1,CSMD1,TRPS1,TSC1,UBC,FAM155A,TOM1L2,ZNF711,SPHK2,REEP1,MAP3K12,MFF,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-301b:PITA hsa-miR-301b:PITA_TOP PITA 2.01E-61 1.13E-57 1.04E-60 9.54E-60 133 633 "ASIC1,CCDC85A,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,STK33,NCOA1,ATP2B2,ADGRB3,NRP2,LDLRAD4,THSD7A,USP6,MAGI1,CFL2,SOCS6,PLAA,CLTC,QKI,CNR1,CLOCK,GDA,LRIG1,SOCS5,APPL1,ARHGEF4,PPP6R2,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,FAM107B,DPYSL2,ABCC5,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,SLC43A2,ERBB4,ACSL4,SCML2,MED12L,FOXF2,NBEA,FUT9,GABRA3,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,GRB10,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KIT,MBNL1,CHIC1,AFF1,MYT1,NPTX1,PDE1C,PDE4B,PFKFB3,PIK3C2A,CCSER2,LRP12,RELN,PSD,MTMR10,PTPRD,PTPRG,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,TEX2,CDK19,TSPYL2,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,TACC1,ANKRD12,CAMTA1,FBXW11,TCF4,SATB2,TRIM2,DICER1,ZFPM2,SLC44A1,RIMBP2,R3HDM1,CSMD1,TRPS1,TSC1,UBC,FAM155A,TOM1L2,ZNF711,SPHK2,REEP1,MAP3K12,MFF,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-130a:PITA hsa-miR-130a:PITA_TOP PITA 2.01E-61 1.13E-57 1.04E-60 9.54E-60 133 633 "ASIC1,CCDC85A,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,STK33,NCOA1,ATP2B2,ADGRB3,NRP2,LDLRAD4,THSD7A,USP6,MAGI1,CFL2,SOCS6,PLAA,CLTC,QKI,CNR1,CLOCK,GDA,LRIG1,SOCS5,APPL1,ARHGEF4,PPP6R2,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,FAM107B,DPYSL2,ABCC5,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,SLC43A2,ERBB4,ACSL4,SCML2,MED12L,FOXF2,NBEA,FUT9,GABRA3,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,GRB10,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KIT,MBNL1,CHIC1,AFF1,MYT1,NPTX1,PDE1C,PDE4B,PFKFB3,PIK3C2A,CCSER2,LRP12,RELN,PSD,MTMR10,PTPRD,PTPRG,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,TEX2,CDK19,TSPYL2,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,TACC1,ANKRD12,CAMTA1,FBXW11,TCF4,SATB2,TRIM2,DICER1,ZFPM2,SLC44A1,RIMBP2,R3HDM1,CSMD1,TRPS1,TSC1,UBC,FAM155A,TOM1L2,ZNF711,SPHK2,REEP1,MAP3K12,MFF,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-130b:PITA hsa-miR-130b:PITA_TOP PITA 2.01E-61 1.13E-57 1.04E-60 9.54E-60 133 633 "ASIC1,CCDC85A,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,STK33,NCOA1,ATP2B2,ADGRB3,NRP2,LDLRAD4,THSD7A,USP6,MAGI1,CFL2,SOCS6,PLAA,CLTC,QKI,CNR1,CLOCK,GDA,LRIG1,SOCS5,APPL1,ARHGEF4,PPP6R2,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,FAM107B,DPYSL2,ABCC5,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,SLC43A2,ERBB4,ACSL4,SCML2,MED12L,FOXF2,NBEA,FUT9,GABRA3,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,GRB10,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KIT,MBNL1,CHIC1,AFF1,MYT1,NPTX1,PDE1C,PDE4B,PFKFB3,PIK3C2A,CCSER2,LRP12,RELN,PSD,MTMR10,PTPRD,PTPRG,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,TEX2,CDK19,TSPYL2,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,TACC1,ANKRD12,CAMTA1,FBXW11,TCF4,SATB2,TRIM2,DICER1,ZFPM2,SLC44A1,RIMBP2,R3HDM1,CSMD1,TRPS1,TSC1,UBC,FAM155A,TOM1L2,ZNF711,SPHK2,REEP1,MAP3K12,MFF,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-454:PITA hsa-miR-454:PITA_TOP PITA 2.01E-61 1.13E-57 1.04E-60 9.54E-60 133 633 "ASIC1,CCDC85A,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,STK33,NCOA1,ATP2B2,ADGRB3,NRP2,LDLRAD4,THSD7A,USP6,MAGI1,CFL2,SOCS6,PLAA,CLTC,QKI,CNR1,CLOCK,GDA,LRIG1,SOCS5,APPL1,ARHGEF4,PPP6R2,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,FAM107B,DPYSL2,ABCC5,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,SLC43A2,ERBB4,ACSL4,SCML2,MED12L,FOXF2,NBEA,FUT9,GABRA3,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,GRB10,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KIT,MBNL1,CHIC1,AFF1,MYT1,NPTX1,PDE1C,PDE4B,PFKFB3,PIK3C2A,CCSER2,LRP12,RELN,PSD,MTMR10,PTPRD,PTPRG,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,TEX2,CDK19,TSPYL2,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,TACC1,ANKRD12,CAMTA1,FBXW11,TCF4,SATB2,TRIM2,DICER1,ZFPM2,SLC44A1,RIMBP2,R3HDM1,CSMD1,TRPS1,TSC1,UBC,FAM155A,TOM1L2,ZNF711,SPHK2,REEP1,MAP3K12,MFF,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-222:mirSVR_highEffct hsa-miR-222:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.06E-61 1.15E-57 1.06E-60 9.74E-60 151 822 "RALGAPA1,ACADM,KLHL32,AXIN2,LRFN2,WDR35,SPARCL1,PCDH10,PITPNM2,PARG,APAF1,ASPA,ATP1B3,DPY19L3,BCHE,NAE1,CA8,CACNB4,KRIT1,MAGI1,CLGN,NDST3,C4orf33,QKI,CNR1,AKAP5,CREM,GDA,RGS6,SEC24C,KIAA0040,USP6NL,KATNAL2,GAPVD1,ZFYVE16,KIAA0586,SPATA2,MYEF2,SPOCK3,PDCD6IP,ARRDC4,FCF1,EMX2,ABCA8,SEC24B,SUCO,SMC2,GABRG2,GALC,KIAA1841,NEU3,SULT1C4,GDF9,PPARGC1A,BRD8,LUZP2,FERMT2,GPD2,ZBTB49,ADAMTS6,MAP4K5,MIER3,HNMT,SHISA6,ZNF181,LRRCC1,INSM1,KIT,STMN1,HECTD2,NCOA7,MARK1,MAT2A,MATN2,MEIS1,ADAM22,NEFH,NEK1,NOVA1,CLDN11,CDK18,PDE4B,PFKFB2,RETREG1,PDZRN4,MAGEL2,PPP2R5E,MAPK10,VPS13C,ANKHD1,ZNF615,CEP97,KHDRBS2,RDX,ERI2,RFX3,RGS4,SLC25A36,CARF,RORB,MRAP2,BAALC,SPIN3,MCMBP,SAFB,ZFP30,FERMT1,KIF16B,CPEB3,FBXO11,FNDC3A,SYBU,PPP4R3A,WDR47,CCDC88A,CPEB4,SNCA,TMCC1,ZC3H13,SPART,CLASP2,POGZ,ZNF302,NXT2,ADHFE1,CAMTA1,FAM208A,AGTPBP1,TCEA1,ZFP90,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CYB561A3,ZFPM2,ERCC6L2,TP53BP2,TRPS1,TRIM9,EML6,TUBA1A,SEMA3B,NAV3,PLSCR4,MSRB3,AP3B2" MicroRNA hsa-miR-563:mirSVR_lowEffct hsa-miR-563:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-61 1.15E-57 1.06E-60 9.74E-60 152 833 "RALGAPA1,CLK4,PCDH19,HACE1,TXNDC16,SPARCL1,PCDH10,BBOX1,AMPD2,SUGT1P4-STRA6LP-CCDC180,UPRT,PPP4R4,CADPS,TMEM108,SLC4A4,ATP1B3,ADAM23,DNAJC27-AS1,SYNJ2,MTMR2,IL33,PTBP2,RUNX1T1,PRC1,HECTD1,MAP4K4,IGLON5,AKAP6,ZNF385A,CLIP3,SEC24C,VCAN,CNTNAP2,PPP1R16B,PHF14,PUM1,DCAF4,GAPVD1,MATR3,TMEM170A,JAKMIP2,SV2B,SGSM2,NR1D2,DMTF1,DPP6,DTNA,DNAJB6,E2F5,PHF20L1,EIF5,CALCRL,VPS13B,GPHN,ADGRV1,RACK1,STRADA,ZNF589,SYNCRIP,NOP56,UFM1,ATP2C1,MEGF10,ZNF234,DISC1,ARFIP1,LYVE1,ZNF638,ADGRA3,GPD2,SPACA9,HAS2,MAN1B1,HSPA1L,FAM95B1,SOWAHA,RBPJ,SCIN,KCNN2,MAN2A2,ADAM22,MSR1,MYO7A,HNRNPM,ALDH1L2,NOVA1,DNHD1,SETD4,CHAMP1,OPA1,CNTN3,PCDH9,NALCN,PRIMPOL,ING3,EPB41L4B,SH3KBP1,DRAM2,PPP3CC,GRAMD1C,HYDIN,ANKHD1,PTPRE,USP47,FAT4,KHDRBS2,ERI2,RIC8B,RPL15,LRRK2,RYR3,SALL1,TNFRSF19,SUPT20H,KIF21A,SHC4,FNDC3A,WDR37,ABLIM3,SLC2A5,KANSL3,ATF7IP,GKAP1,IFT122,KIF13A,PDZD2,TRERF1,SOX15,GLT8D1,SPTAN1,ATP10B,POGZ,ITPRID2,PHLDB1,ALG1,ADGRL3,KLHL4,SATB2,TRIM2,TIAM1,BHLHB9,TRO,PPIL6,TSN,TTC3,TBC1D15,XPO1,REEP1,AMZ1,DPYSL5,EMSY,STOX2" MicroRNA hsa-miR-137:PITA hsa-miR-137:PITA_TOP PITA 2.32E-61 1.30E-57 1.19E-60 1.09E-59 121 518 "ABHD6,FMNL2,TMEM132B,RNF150,INTS2,OSBPL8,C1QTNF3,UNC79,TRMT9B,PITPNM2,SHROOM2,CADPS,ARHGEF7,CACNA1G,DCLK1,FOXN3,SOCS6,NRXN3,FAM19A5,QKI,COL4A5,ABI3BP,BAG4,ZNF385A,RGS6,CSNK1G3,RIMS4,ZFYVE16,MAML1,DGKG,YTHDC1,ZC3H11A,RHOBTB1,SLC12A6,EDIL3,FRY,MBNL2,EIF1,RCAN2,SLC43A2,ERBB4,FGF11,PRKAG2,NBEA,MEGF11,GPR162,PPARGC1A,LUZP2,GPD2,BACH2,MIER3,HLF,IL6R,KCND1,KIT,LRP1B,MEF2C,MITF,MSI1,NEFH,NF1,NFIX,NOVA1,GPR137C,CNTN3,PDE4D,PDE1B,GPR85,TMOD2,LRP12,LRRN3,PPP5C,DIRAS2,WBP1L,SNRK,PTN,PTPRB,NKAIN1,OXR1,MSANTD2,ZMAT4,MORC4,RIC8B,STX1B,PPM1E,CHD9,PPP4R3A,SLC6A8,SLC8A1,SLC12A2,FAM126B,SOX11,NFASC,NKAIN2,SS18,ERBIN,NXT2,STAC2,SEPT3,PLCB1,SYT1,ANKRD12,TCF4,SATB2,RPGRIP1L,TCF12,ZFPM2,AP4E1,AKTIP,TRPS1,TSN,UBE2H,BCL2L13,MGAT5B,WNT7A,SLC30A4,EMSY,RGS7BP,HNRNPA3,PHTF2,MSRB3" MicroRNA hsa-miR-3171:mirSVR_highEffct hsa-miR-3171:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-61 1.43E-57 1.31E-60 1.21E-59 181 1174 "RALGAPA1,FMNL2,AXIN2,HECW2,PCDH19,OSBPL8,SPOP,CEP126,PCDH10,FAM135A,ZFAT,PHF12,PKP4,APC,ZSCAN18,DPY19L3,TTLL9,BID,DST,IL33,CALB1,KALRN,ZNF501,ENTPD6,L3MBTL4,CFL2,FOXN3,CHN2,NDST3,PPT2,MYRIP,ARHGEF10,VCAN,PDE4DIP,RIPOR2,KIF26A,MATR3,DDX46,ALKBH8,PLPPR4,SACS,NR1D2,ACOT8,DTNA,ECM2,DNAJB6,DNM1L,AASDH,SNX29,KLHL5,OPTN,PHF20L1,APH1A,EIF4G2,RGS17,PCOLCE2,ENO2,ETV1,F8,ARMCX1,FAM198B,DLC1,MED12L,POLR1B,POLK,PCYOX1,FLT1,PSD2,NELFCD,WDR83,ZNF605,ST6GALNAC3,STAU2,MSANTD4,AP4B1,MPP6,OGA,MEGF11,HRASLS5,GABRA3,SYT17,KIAA1841,GATM,MSTN,ZNF782,GRIA2,PLCD4,FAM19A2,BVES,AP4S1,ADAMTS6,FAM222A,HAS2,MIER3,MSL1,JAK2,STXBP5,LAMP2,HECTD2,NCOA7,SHC3,MEIS1,POC1B,MMP16,ADAM22,MSR1,MYCN,MYO6,NFE2L2,VWA2,FAM98B,ING3,RANBP3L,EPDR1,BCAS3,DEF8,TMEM260,PPP2R3C,SLC25A48,USP47,SUSD4,RBBP6,TRIM68,ERI2,MORC4,RFX2,CARF,ROBO1,EPHA10,PTGR2,ZNF331,AP1AR,DGLUCY,ATXN2,SCP2,HES6,HKDC1,FBXO11,ANKRD6,PREX2,SLC2A5,SLC9A5,SMARCD3,ANKRD36,LIMCH1,BDP1,TEX2,LMO3,ATP10B,TTBK2,STXBP1,TACR1,ZFP90,SYNE1,DOCK9,PCDHA2,FRYL,AP4E1,SLC44A1,MTMR14,TIMP4,NR2E1,TMPO,C9orf85,RUNDC3B,MTCH1,LGI4,ZIC1,MICU3,ZNF28,TRIM9,MKRN3,LYPD6,ZNF184,SMARCAD1,UPF3A,LINC02210,STOX2,ADAMTS9,KAT6A,NLRP3" MicroRNA hsa-miR-141:PITA hsa-miR-141:PITA_TOP PITA 3.67E-61 2.05E-57 1.88E-60 1.73E-59 132 626 "PCDH19,RTL9,OSBPL8,SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,STX16,ST3GAL5,CACNA1I,LDLRAD4,SPAG9,SEPT7,CCPG1,CFL2,FOXN3,QKI,HECTD1,MAP4K4,MYRIP,CLOCK,CDC42BPB,CSNK1E,CSNK1G3,ERC2,APPL1,KIAA0408,DOCK4,HDAC4,TM9SF4,DAPK1,ARMCX2,YTHDC1,LYPD1,SNAP91,GRIN3A,CPEB2,YAF2,STX2,DLC1,FGF13,AFF2,SMC2,MSANTD4,MEGF10,SRCAP,PPARGC1A,TCERG1,KDM2B,GPD1,TMEM121B,PCLO,GRB10,GRIN2D,MIER3,HLF,ACOT7,IPO5,STXBP5,TTYH2,MARK1,MBNL1,CHIC1,MN1,MYO5A,NEXMIF,NPTX1,NRCAM,GPR137C,PCDH8,PCDH9,CCSER2,PLCL1,TRHDE,SCHIP1,PPP2R2B,PPP2R5E,VSTM2L,GDPD1,SNRK,PTCH1,PTPRD,PTPRG,KHDRBS2,SNX22,ATXN7,SCN2B,SCP2,SUPT20H,HSPA4L,PPM1E,CPEB3,CHD9,TET1,CPEB4,RCOR3,MBD5,PDZD2,SOX11,SP4,NFASC,LMO3,CLASP2,ITPRID2,SEPT8,TTBK2,STXBP1,KLHL7,NECAB1,TCF4,TCF12,SIRT1,ZFPM2,TIAM1,KAT6B,TNS1,NR2C2,TSC1,UBE2H,UBE3A,WIPF1,CLDND1,ZNF711,ZNF24,EMSY,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-200a:PITA hsa-miR-200a:PITA_TOP PITA 3.67E-61 2.05E-57 1.88E-60 1.73E-59 132 626 "PCDH19,RTL9,OSBPL8,SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,STX16,ST3GAL5,CACNA1I,LDLRAD4,SPAG9,SEPT7,CCPG1,CFL2,FOXN3,QKI,HECTD1,MAP4K4,MYRIP,CLOCK,CDC42BPB,CSNK1E,CSNK1G3,ERC2,APPL1,KIAA0408,DOCK4,HDAC4,TM9SF4,DAPK1,ARMCX2,YTHDC1,LYPD1,SNAP91,GRIN3A,CPEB2,YAF2,STX2,DLC1,FGF13,AFF2,SMC2,MSANTD4,MEGF10,SRCAP,PPARGC1A,TCERG1,KDM2B,GPD1,TMEM121B,PCLO,GRB10,GRIN2D,MIER3,HLF,ACOT7,IPO5,STXBP5,TTYH2,MARK1,MBNL1,CHIC1,MN1,MYO5A,NEXMIF,NPTX1,NRCAM,GPR137C,PCDH8,PCDH9,CCSER2,PLCL1,TRHDE,SCHIP1,PPP2R2B,PPP2R5E,VSTM2L,GDPD1,SNRK,PTCH1,PTPRD,PTPRG,KHDRBS2,SNX22,ATXN7,SCN2B,SCP2,SUPT20H,HSPA4L,PPM1E,CPEB3,CHD9,TET1,CPEB4,RCOR3,MBD5,PDZD2,SOX11,SP4,NFASC,LMO3,CLASP2,ITPRID2,SEPT8,TTBK2,STXBP1,KLHL7,NECAB1,TCF4,TCF12,SIRT1,ZFPM2,TIAM1,KAT6B,TNS1,NR2C2,TSC1,UBE2H,UBE3A,WIPF1,CLDND1,ZNF711,ZNF24,EMSY,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-4308:mirSVR_lowEffct hsa-miR-4308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-61 2.12E-57 1.94E-60 1.78E-59 197 1380 "ACADM,EMILIN3,KLHL32,PTCHD1,DPY19L2P4,ZNF578,AMT,ANK2,SEMA7A,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,AQP6,ARNTL,ARRB1,PLA2G4C,N4BP2L1,ATP6V1G2,TTLL9,ADGRB1,DST,IL33,CALB1,RUNX1T1,LDB2,METTL6,AP4M1,LARGE1,UBE2L6,CNOT8,C4orf33,MAP4K4,PCYT1B,COX4I1,AHCTF1,TOGARAM2,MYRIP,CPS1,CLOCK,C2CD2,RBM39,OSBPL3,PPP1R16B,ERC2,CTH,RUBCN,ARHGAP24,EARS2,DAPK1,GRIN3A,DTNA,DNAJB6,WDPCP,PHC2,YAF2,SUGP2,APH1A,RASA4,ELN,USPL1,EPB41,RCAN2,GPHN,VPS26C,PTK2B,FCGR3A,GORAB,FGF11,FGFR3,SCARA3,EVL,NBEA,CAMKK2,ZNF605,MPP6,GAD1,INPP5K,SRCAP,GFER,MMADHC,TTBK1,GLYR1,STARD3,KCNMB4,SERP2,LINC01089,SOX21,LINGO1,RNFT2,FAM222A,TOX2,ARHGAP36,AGBL5,RBPJ,C2CD4C,HECTD2,PIK3AP1,ZFYVE27,MAT2A,ADAM11,MEIS2,PPM1L,MSI1,MYO7A,RTL5,PCBP3,P2RX7,PDE1C,PDE4D,GNG2,PFKFB4,OLA1,FAM218A,TMEM38A,PLCL1,LRP12,ING3,POU6F1,MINDY2,PPP1R1A,GRAMD1C,WBP1L,CNTLN,MTMR10,PTPRB,PTPRE,C1orf109,ZSCAN2,CEP97,SH3TC2,ROGDI,ZDHHC14,RDX,RET,PRIMA1,KCTD17,RIC8B,RNASEL,RNH1,TMLHE,CYB561D1,SNX22,RPL15,EMID1,MEG3,STX1B,CCDC112,AP1AR,PRCD,SMPD3,KIF27,FERMT1,ASAP3,WDR37,WDR47,FAM214B,CCDC88A,TRIM67,SLC12A2,SLC14A1,GKAP1,SMARCC2,CMTR2,SNRPN,SEPT8,ADHFE1,SYN2,SYP,TACR1,NAT16,CYB561A3,C18orf54,TIAM1,FAM124A,CDK20,NPL,WBP2,SYNPO2,NEIL2,KCNE5,FAM155A,UGT8,WIPF1,CLDND1,RICTOR,CRB2,CELF4,REEP1,FSTL5,SLC38A1,LINC02210,SEMA3B,UBE3B,KAT6A,LAS1L,PRRT4,FAM198A" MicroRNA hsa-miR-142-5p:PITA hsa-miR-142-5p:PITA_TOP PITA 5.17E-61 2.89E-57 2.64E-60 2.43E-59 143 741 "RALGAPA1,CLK4,CCDC85A,USP31,ALCAM,FAM135A,CDC42BPA,GAS7,ZBTB10,SLC4A4,ADGRB3,SYNJ1,SGCE,CAMK2A,SPAG9,LDB2,CCNH,SEPT7,CCPG1,NRXN3,CLCN3,QKI,MAP4K4,ARMC8,AKAP5,SLC35F1,CRY2,CSNK1G3,APPL1,FAM131B,HDAC4,SPOCK2,RHOBTB1,SACS,SPOCK3,FAM107B,NR1D2,CPEB2,KMT5B,EGR3,CALCRL,ERBB4,ETV1,MED12L,FGF13,NBEA,FAM49B,ST6GALNAC3,CHL1,LUZP2,GPR37,CIT,RNF165,ADAMTS6,BACH2,MIER3,CELF5,IGF1,IL6ST,KIT,IPO5,L1CAM,LIFR,SFXN5,NCOA7,MBD1,LRP1B,MEIS1,MEIS2,KITLG,MKLN1,MYCN,NEXMIF,NFE2L2,NTRK3,PDE4D,PIK3C2A,RETREG1,LRP12,SCHIP1,RETREG2,MINDY2,PPP3CA,MTMR10,PTPRD,CEP97,TMEM255A,FAM184A,RBBP8,REV3L,FIGN,RIC8B,PBRM1,ZFHX4,ALG9,ROBO1,BAALC,ST6GALNAC6,RTN1,RYR3,RMI1,FNIP1,SUPT20H,HSPA4L,CPEB3,SHC4,CHD9,FNDC3A,CCDC92,FAM81A,BTBD3,SLC11A1,CPEB4,MBD5,SOX11,SP2,STAU1,RGL1,SEPT3,ANKRD28,TACC1,ANKRD12,CAMTA1,ADGRL3,FBXW11,TCF4,TRIM2,TCF12,PUM2,SIRT1,ZFPM2,SLC44A1,TIAM1,TNS1,STXBP4,FAM155A,ZBTB38,PRDM8,SLC17A7,PLSCR4,JMJD1C,NETO2,ST8SIA2" MicroRNA hsa-miR-138:mirSVR_highEffct hsa-miR-138:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.29E-61 3.52E-57 3.21E-60 2.95E-59 154 862 "ACADM,ABHD6,SYS1,UNC5A,PWWP2A,ZFAT,SUGT1P4-STRA6LP-CCDC180,PKP4,VAT1L,TNRC6C,CDK10,STK33,ZSCAN18,STX16,ATP2B2,DPY19L3,ADAM23,BACH1,SEC11C,JAZF1,CAST,LRRFIP1,NRXN3,AKAP7,IQCK,LETMD1,ZNF521,ZNF385A,SLC35F1,FAM171B,HINFP,ANKRD44,MROH8,SNCAIP,SEC24C,SUSD5,SOCS5,FAM169A,RIMS2,DCAF4,ARHGAP32,KIF26A,DGKG,IP6K1,GIT2,ARMCX2,MYEF2,ELMO1,TMCC2,CHRDL1,USP3,DTNA,DNAJB6,SNX29,PHF20L1,APH1A,KMT5B,RCAN2,GPHN,SRRM1,RASL12,CLVS1,ST3GAL6,BAIAP2,POLK,MEX3B,RGPD5,NBEA,PDLIM5,OGA,MEGF10,KIAA1841,PPARGC1A,CRCP,GLI2,ZNF638,GNAO1,FERMT2,GPD1,LPAR4,PCLO,RBPJ,STXBP5,MAP4,MEIS2,MOV10,MXI1,NDP,OGG1,PDE3A,GPR85,GNG2,ZNF655,PCDH18,PRIMPOL,SCHIP1,EPB41L4B,FSD1,VSTM2L,RELN,SAMD9,NKAIN1,PID1,USP47,RAD51D,MSANTD2,RGS3,ARMC5,YY1AP1,CLIP1,ZNF354C,ZNF568,TNFRSF19,FNDC3A,CCDC88A,KBTBD4,MYH15,ANKRD36,LIMCH1,SNRPN,USP33,BDP1,ERC1,SPTAN1,NFASC,PBLD,ZC4H2,KANK1,SULF2,NSFL1C,VPS13A,TPCN2,ARHGAP9,SIRT1,DICER1-AS1,ZFPM2,SLC44A1,ARL10,NPL,ELP5,AMACR,TRO,TRPS1,RUSC1,CFAP298,PCDH20,ZFP37,ZNF19,SLC17A7,FIP1L1,CASC15,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-1273d:mirSVR_highEffct hsa-miR-1273d:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.53E-61 3.66E-57 3.33E-60 3.07E-59 157 896 "CLK4,GALNT13,BEND6,ZNF608,MTUS1,OSBPL8,C1QTNF3,UNC79,ALK,PITPNM2,SUGT1P4-STRA6LP-CCDC180,SPTBN4,ARNTL,RGS20,LINC00173,ATP1B3,RIPK1,DST,FUBP1,NAE1,JAZF1,AP1M1,KALRN,SLC25A14,VXN,CLDN10,CCNH,LRBA,MAGI1,TIGD7,CLGN,SRSF11,MS4A7,CNOT8,RAB33A,NRXN3,MAP4K4,FHL5,AKAP6,WHRN,SLC4A8,SUSD5,PITPNM3,CCDC144A,DCAF8,LONRF1,DGKB,GIT2,TIAM2,DDX46,RHOBTB1,DYNC1I1,CPEB2,DPP6,DTNA,DTNB,ABCC5,AASDH,EDN1,FRY,AASS,COPS4,EIF1,EMX2,DENND4A,SPEG,FCGR1A,GORAB,FER,FHL1,NBEA,OGA,ARFIP1,GGTA1P,ZNF638,MAP4K5,HAS2,PADI2,ARHGAP36,ZIC5,SLC35G1,KCNH2,LAMP2,SMAD1,MARK1,MEF2C,KITLG,POC1B,NF1,SLC11A2,NRCAM,CNTN3,SLC10A4,GPR85,NLGN3,ZNF655,PLCB2,PLCL1,MAPKAP1,SCHIP1,ING3,PPM1B,TATDN3,PPP3CA,RASGEF1B,HYDIN,CNTLN,ZSCAN32,RAP1GDS1,ZNF532,ROBO1,STK32B,LRRK2,SEMA6D,SCP2,SGK1,ZFP30,CHD9,FNDC3A,FHOD3,FAM214B,SLC8A1,NAPB,HECW1,KDM4C,ZBTB43,RBM26,PBLD,ITPRID2,NKAIN2,KANK1,PRRC2C,PLCB1,TCF4,TRIM2,GPRIN3,HEY1,TMPO,NEIL2,AMACR,STXBP4,TSC1,UCHL1,VLDLR,CLDND1,ZNF540,ZNF184,SLC30A4,RNF103,TUBA1A,FAM47E,PDSS2,AMN1,FXR1,FRMD6,RNF146,GAN" MicroRNA hsa-miR-1225-3p:mirSVR_lowEffct hsa-miR-1225-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.12E-61 4.54E-57 4.14E-60 3.81E-59 179 1158 "DGCR6,KDM5D,NDRG2,GALNT16,ADCY6,OSBPL1A,TBC1D14,KIAA1324,CC2D2A,AK2,FGD2,MYH7B,PKP4,BCAS1,SEMA4G,MADD,NUMB,RIPK1,ADAM23,TTLL9,CFLAR,BMP7,LURAP1,CABP7,KALRN,SLC25A14,CBS,CD86,CDC25B,CDH2,CRLF1,NUMBL,PLEKHB1,EPS15L1,CPNE6,TMEM184B,LETMD1,COL11A2,COX4I1,ZNF385A,SH2B1,CST3,RIMS2,PPP6R2,GPSM1,DCAF8,DBI,AIF1L,GIT2,ELMSAN1,ZBTB24,C2CD2L,RHOBTB1,DMPK,DUSP9,E2F5,AASDH,RASA4,ELN,PAN3,EPB41,LRRC17,CEP85L,EZH1,SCML2,FGF14,FGFR1,ATP13A4,SYT3,POMT1,APOPT1,UFM1,STAMBP,ERGIC3,CELF1,BRSK1,TVP23A,GABRB3,KIAA1841,ALDH1L1,SULT1C4,GFER,GFRA2,CSDC2,MSL3,STARD3,LILRB4,ADAMTS13,PRDM5,UBE2QL1,ELOVL5,HMGCL,ZDHHC15,C2orf72,TJAP1,INPP5B,ITPKB,KCND1,CREG2,A1BG-AS1,STMN1,MAP4,ADAM11,PTOV1,LYRM9,MYO7A,NOVA2,NPTX1,PCBP3,NTRK2,NTRK3,TBC1D25,OLA1,ZDHHC8,ZNF655,PPP1R1A,NKAIN4,PPP5C,PRKAB2,PRKACB,SLC26A11,DCHS2,RELN,NDUFS7,ACSM5,TUG1,CEP97,RGS12,KLHDC8A,GSTCD,YY1AP1,KCNIP3,STX1B,CSRNP3,GALNT10,HKDC1,SLC2A5,SLC6A11,SLC9A5,ABTB1,TTC17,FAM219A,SP2,ZSWIM8,IZUMO4,KDM4C,TEX2,SPTAN1,IQSEC2,NFASC,MESP1,NKAIN2,SSPO,SEPT8,NSFL1C,TACC1,SATB2,PHF24,NSD1,ARL10,MTMR14,TK2,TLR4,TNS1,PIK3R5,WBP2,AMACR,NUTM2A,VAV1,LGI4,CFAP298,ZBTB14,CRB2,PRTFDC1,NT5M,GDPD5,ADAMTS9,DOCK8,GJC2" MicroRNA hsa-miR-323b-5p:mirSVR_lowEffct hsa-miR-323b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.25E-61 4.62E-57 4.20E-60 3.86E-59 174 1097 "GALNT16,ADCY6,ADD2,KIAA1211,HECW2,KLHL13,CC2D2A,TRMT9B,FGD2,LGR5,AQP6,CADPS,CDK13,ATP6V0A1,ZNF599,CACNB4,LURAP1,HIP1R,PRC1,ARHGAP33,LARGE1,MAGI1,NUMBL,B4GALT6,RAB28,NRXN3,AKAP6,LETMD1,SMARCAL1,CNRIP1,CLOCK,CRMP1,SOCS5,PDE4DIP,DOCK4,JAKMIP2,MFAP3L,POM121,RHOBTB1,SACS,SV2B,MTX3,CHRDL1,GRIN3A,DNM1,DMPK,DOCK2,ECM2,EDNRA,KLHL5,KMT5B,RGS17,PAN3,ENO2,MRPL37,CDKL3,NSRP1,RACK1,ST3GAL6,SEC24B,MEX3B,IP6K2,CELF1,STAU2,ABLIM2,GABRB3,IQGAP2,ERAP1,WASHC2A,LYVE1,BRD8,TCERG1,MSL3,ZNF638,GPD2,PCLO,PLCD4,GRM2,GRM8,CIT,LINGO1,PSIP1,RNFT2,HAS2,PADI2,SCIN,LINC00634,A1BG-AS1,IPO5,STXBP5,STMN1,MAN2A2,AQP11,MATN3,MBD1,CHIC1,KCTD6,MMP16,LAYN,MYO7A,NME4,OCRL,LOC100128398,P2RX7,GLIPR1L2,PALM,PCDH8,PCDH9,PCSK5,PDE4A,PFKFB3,SLC25A23,SMIM7,PURG,STRN3,RETREG2,PPP2R5E,CEP41,DIRAS2,BDNF-AS,TMEM231,ZNF844,RBBP6,RNH1,CCDC25,RORB,FBXW7,PTGR2,KCNIP1,SUPT20H,PPM1E,KIF16B,FHOD3,NUBPL,WDR37,SLC6A8,ANKRD36,KDM4B,DOP1A,PDZD2,NFASC,LHPP,NEK4,DIP2A,SEPT3,SYN2,MLST8,TBCEL,CUX2,PUM2,TNS2,ITGB3BP,TMPO,PRRT1,ZNF346,PDSS1,TRO,TRPS1,DCBLD1,TTC3,UBE3A,UGT8,MGAT5B,VSNL1,PCDH20,ZNF23,EML6,CADM2,PRDM10,NAV3,PARP11,DOCK8,FBXO36,LAS1L" MicroRNA hsa-miR-1257:mirSVR_highEffct hsa-miR-1257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-60 5.77E-57 5.24E-60 4.83E-59 166 1003 "FMNL2,GALNT13,AP2A2,HACE1,OSBPL1A,OSBPL6,ARHGAP20,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APLP1,SEMA4G,CADPS,LINC00173,STK33,NCOA1,ATP1B3,BACH1,C5,CA8,CACNA1B,KALRN,SPAG9,METTL6,USP6,SEPT7,TIGD7,CLGN,NDST3,QKI,ARHGEF6,AKAP7,FAM149A,RCHY1,TBPL1,CPS1,CREM,RNF14,SNCAIP,ERC2,ZSCAN23,ARHGAP32,SPOCK2,ZC3H11A,RHOBTB1,CHRDL1,NYAP1,USP3,DMTF1,PDCD6IP,EDNRB,FSD1L,FAM13A,PAN3,TUBD1,LRRC17,EXTL2,FAM198B,IP6K2,SYNCRIP,EFCAB2,NBEA,ERGIC3,ERAP1,ZNF559,MSTN,SESN1,CRCP,MSL3,GNAL,ZNF782,PRUNE2,FUT10,GPR37,PLPP7,CIT,FRMD3,HMGCR,C9orf129,SMAP1,MSL1,ZIC5,IL12A,INPP1,KCNJ5,IPO5,HECTD2,PIK3AP1,MAN2A2,LYPLAL1,MARK3,MEIS1,MXI1,MYO6,MYO9A,NCAM2,VWA2,NRCAM,NTRK2,ENPP2,PIK3C2A,EPB41L4B,EPDR1,PTPRO,SH3TC2,FAT4,MSANTD2,REV3L,PRRT2,RFX2,CARF,PNMA8A,NEK11,ZNF568,AP1AR,SAFB,SEMA6D,CSRNP3,ATXN2,SUPT20H,SHC4,FNDC3A,NLGN1,SLA,EPN2,CCDC88A,RCOR3,PDZD2,FNBP1,MYCBP2,CDK19,LMO3,CLASP2,TROVE2,ZSCAN29,SEPT8,ADHFE1,JMJD6,VPS13A,TMEM150C,FAM208A,ADGRL3,DMXL2,NSD1,FAM200B,WBP2,RUNDC3B,TRO,TBC1D15,WIPF1,CLDND1,XRCC4,ZNF17,ZNF28,KCNT2,TRIM9,ATP6V0E2,LYPD6,SPIRE1,EMSY,WNK3,WNK2,PLSCR4,HNRNPA3,FBXO36,NETO2" MicroRNA hsa-miR-646:mirSVR_highEffct hsa-miR-646:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-60 6.01E-57 5.46E-60 5.02E-59 152 843 "RALGAPA1,ACADM,KLHL13,TAOK1,FAM135A,ALK,NT5C3B,TNRC6C,AQP6,STK33,BACH1,CFLAR,NAE1,JAZF1,IL33,CA4,LURAP1,LDB2,LRBA,NDST3,NRXN3,HECTD1,LY86,CNTN1,AKAP6,ABI3BP,AHCTF1,BAG4,ZFP28,AKAP12,ARHGEF10,DZIP3,CTH,USP6NL,DOCK4,GAPVD1,ARHGAP24,DCAF8,IST1,SCRN1,MYEF2,KIAA0753,ZC3H11A,ARRDC4,DNM1L,FRY,TENM1,VPS13B,RCAN2,NRN1,ARMCX1,ACSL4,TAOK3,DLC1,FKTN,GORAB,SLC9B2,SCARA3,IP6K2,NBEA,SMC2,TPPP3,GABBR1,GABRG2,PPARGC1A,BRD8,RAB30,ZNF638,MAP7D2,CCDC184,LPAR4,STMN2,DIDO1,BVES,FRMD3,ACOT7,SMAP1,IRF8,IDH3A,C2orf72,NKD1,ZIC5,RBPJ,TJAP1,FAM69A,KIF2A,KIF5A,LAMP2,SYTL4,NCOA7,ASPRV1,PACRG,LYPLAL1,MOV10,SLC11A2,OCRL,PIK3R1,PURG,SH3KBP1,HYDIN,GDPD2,MTMR10,RBBP6,ERI2,SLC25A36,ZFHX4,ROBO2,YY1AP1,RPE,ATAT1,KIF21A,KIF16B,CHD9,FNDC3A,TET1,ZFP1,MBD5,SNRPN,TMCC1,TRERF1,ZSWIM8,ZBTB43,POGZ,KANK1,MTCL1,CAMTA1,SATB2,ZEB1,TPCN2,SIK3,ITGB3BP,MTMR14,NR2E1,ERCC6L2,ELP5,NEIL2,AMACR,DCBLD1,TSC1,HSPBP1,RPRM,PLEKHH2,TBC1D15,XRCC4,PCDH20,ZNF74,LAMP5,PRDM10,RNF103,RTN4,FXR1,GAN" MicroRNA hsa-miR-214:mirSVR_highEffct hsa-miR-214:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-60 6.86E-57 6.21E-60 5.72E-59 157 900 "KCNH8,SYS1,KLHL32,BRAP,PWWP2A,ADRA1D,AP2A2,INTS2,C1QTNF3,FAM135A,OGT,RGS9,SCAPER,IL33,DDR1,LURAP1,CALB2,THSD7A,PTBP2,LRRFIP1,DLGAP1,SRSF11,RAB33A,PLAA,PPT2,QKI,FAM149A,COL4A5,TBPL1,ENTPD4,CS,SEC24C,SOCS5,PHACTR3,PUM1,DCAF4,HDAC9,RIPOR2,DGKG,GIT2,JAKMIP2,MYEF2,C2CD2L,SV2B,DMPK,ABCC5,SEMA3D,YAF2,PHF20L1,ING4,DCTN4,F8,CLVS1,TAOK3,FGF1,FGF14,FHL1,IP6K2,SYNCRIP,IQCG,NELFCD,TMEM107,FAM49B,ATP2C1,ZNF274,SULT1C4,GPR162,SESN1,AHDC1,USP19,PCDH17,DHRS4,ZNF638,KCNMB4,GNAL,ZNF782,TDRKH,PCLO,BTN2A1,FAM19A2,RNF165,RNFT2,SLC2A6,MAN1B1,SHISA6,MSL1,IGF1,ZIC5,KCNB1,KCNN1,KIF5A,MAP6,MITF,NF1,NINJ2,VWA2,NUCB2,IGSF11,LOC100128398,PDE4A,GPR85,ABCB1,SEPT4,PPM1B,HYDIN,RELN,QRICH1,BDNF-AS,PTH1R,TMEM260,PPP2R3C,PID1,TMEM255A,OXR1,GTDC1,EXD2,SPIN3,STK32B,SALL1,ATXN7,TRA2B,CHD9,CNKSR2,ABLIM3,DHX30,KDM4D,SLC8A1,SLC11A1,CPEB4,IFT122,ANKRD36,RBM34,DBNDD2,RGL1,NSFL1C,MMS19,DMXL2,TPCN2,DOCK9,HIF3A,SIK3,TEK,SIRT1,TIAM1,FAM155A,UCHL1,UGT8,P2RY12,PCDH20,POLR3H,ANKS1B,SPIRE1,PRDM10,PPP1R3F,PLSCR4,SMIM8,GAN" MicroRNA hsa-miR-545:PITA hsa-miR-545:PITA_TOP PITA 1.43E-60 8.00E-57 7.25E-60 6.67E-59 134 653 "FMNL2,GALNT13,USP31,INTS2,KLHL13,PCDH19,OSBPL6,OGT,CDC42BPA,APBB2,USP37,NCOA1,ATP2A2,JAZF1,LDLRAD4,CACNB4,HAP1,CAMK2A,CAMK2G,DCLK1,CCPG1,CFL2,SOCS6,CHN2,NRXN3,QKI,HECTD1,AKAP5,MAGED1,IGDCC3,LRIG1,CSNK1G3,ERC2,APPL1,ARHGAP24,HDAC4,GIT2,SPATA2,ELMSAN1,MYEF2,ALKBH8,USP3,CPEB2,PDCD6IP,ABCC5,EDNRA,KMT5B,EGR3,GOLGA7,EIF4G2,PLEKHA1,PAN3,RCAN2,EPHB1,ETV1,ACSL4,MED12L,AMOTL2,MEX3B,AFF2,SYT3,SARAF,ARFIP1,GHR,GNAO1,GPD1,GPD2,TDRKH,CIT,BACH2,KCND2,SMAD1,MARK1,MBNL1,CHIC1,LRP1B,NEXMIF,NFIX,NRCAM,PRTG,PDE4D,ENPP2,PDPK1,PIK3R1,LRP12,RASGEF1B,RELN,PTCH1,MTMR10,PTPRD,TMEM255A,USP47,RBBP6,RDX,ZFHX4,ZNF532,SGSM1,RMI1,PRCD,SCP2,PPM1E,CPEB3,CHD9,R3HDM2,FAM214B,SLC11A1,CPEB4,SNAP25,FAM219A,CDK19,ZNF621,LARP4,TTBK2,STAC2,SYN1,SYP,SYPL1,CAMTA1,ADGRL3,TBL1X,DICER1,ZFPM2,AP4E1,ENHO,TP53BP1,WBP2,TSC1,FLRT2,ZBTB14,NDRG4,REEP1,HNRNPA3,RNF146,SENP7" MicroRNA hsa-miR-616:mirSVR_highEffct hsa-miR-616:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-60 8.56E-57 7.74E-60 7.13E-59 149 812 "KCNH8,SYN3,ABHD6,ADD1,AXIN2,PWWP2A,MTUS1,KCTD16,BBOX1,ANK2,MAGEE2,TMEFF1,SPTBN4,ZFYVE28,ZNF583,BACH1,MTMR2,CACNA1B,THSD7A,CAST,LDB2,CHGB,NDST3,PLAA,VAX2,QKI,ARHGEF10,SOCS5,RIMS2,FAM131B,DOCK4,IST1,DAPK1,AIF1L,YTHDC1,HEPH,SNAP91,WDR20,USP3,DTNA,TOM1,DNM1L,EDNRB,FAM13A,PLEKHA1,EPB41L2,EPHB1,NCALD,ANKMY1,CLVS1,CEP78,FGF1,ATP13A4,COQ5,C2orf88,SMC2,PDLIM5,FAM49B,CELF1,STAU2,OGA,GAD1,LRRC37A6P,KIAA1841,ZNF276,ZNF638,ZNF782,LILRB4,GPR12,STON1,GRIA2,FAM19A2,ADAMTS6,MIER3,SYNPO,USP51,DHX35,KIF5A,SYTL4,MAT2A,MBNL1,MEIS1,MKLN1,LAYN,MYO9A,NF1,NNAT,CLDN11,PCDH9,ENPP2,FAM218A,ANKRD16,PMP22,ING3,IRX1,PPP2R5E,PPP3CA,MAPK9,MAPK10,PTPRE,FAM66C,ENOX1,ZNF493,OXR1,RASGRF2,REV3L,RGS12,RIC8B,RORB,YY1AP1,ATP8B4,TCP11L1,CCDC112,AP1AR,SGK1,FERMT1,DZIP1,SLC2A5,SLC12A2,MYH15,ZC3H13,RBM26,NFASC,ATP10B,THSD1,SS18,NXT2,SYNE2,NUDT10,PLCB1,MLST8,KLHL4,TRIM2,RPGRIP1L,ARHGAP9,TEK,AKTIP,SYNPO2,STXBP4,ANKRD20A2,FLRT2,CLDND1,ZNF711,TCEAL7,RNF103,FIP1L1,UBE3B,FBXO36,NLRP3" MicroRNA hsa-miR-203:PITA hsa-miR-203:PITA_TOP PITA 2.23E-60 1.25E-56 1.13E-59 1.04E-58 131 625 "RALGAPA1,XKR4,NDRG3,FMNL2,ZNF608,PCDH19,KCTD16,RTL9,OSBPL1A,OSBPL8,SEMA6A,AMPD3,MAP4K3,APC,ARNTL,CDK13,SLC4A4,STX16,DPY19L3,MPDZ,BCL7A,SYNJ1,WASF1,CABP7,THSD7A,ZMYM4,MAGI1,NUMBL,FOXN3,SOCS6,CLTC,QKI,HECTD1,CNTFR,AKAP7,AKAP6,CLOCK,RBM39,GDA,ARHGEF10,MATR3,DGKB,NR1D2,EDN1,EDNRA,MBNL2,EGR3,TENM1,TMEM35A,PAN3,NCALD,ETV1,OLFM1,PRKAG2,AFF2,NBEA,GABRB3,GATM,PPARGC1A,TOX3,GNAO1,PCLO,CIT,ADAMTS6,BACH2,NEGR1,LRRCC1,KIF2A,IPO5,MAP2,MBNL1,MEF2C,MEST,MGAT3,MID1,MXI1,ZC3H12B,NFYA,NOVA1,TBC1D25,CNTN3,PDE4D,GPR85,PIK3C2A,POLG,MAPK9,MAPK10,PTCH1,PTPRG,RADX,SLC25A36,ZFHX4,ZNF532,ROBO1,CHD9,WDR37,ABLIM3,BTBD3,SLC12A2,TET1,CPEB4,FAM126B,DOP1A,SP2,SP4,NMNAT2,CLASP2,LARP4,NKAIN2,CEP68,PHLDB1,ADAMTS17,TCF4,DMXL2,KIAA0930,TRIM2,RPGRIP1L,TCF12,DICER1,KAT6B,TRPS1,SGK3,FAM155A,VSNL1,TMEM237,SMARCAD1,PRDM10,KAT6A,PHTF2,NETO2,GAN" MicroRNA hsa-miR-1275:mirSVR_highEffct hsa-miR-1275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-60 1.43E-56 1.29E-59 1.19E-58 155 882 "ABCF1,KCNH8,ACHE,ABHD6,NDRG3,NDRG2,AXIN2,ADRB2,HECW2,CC2D2A,SPOP,LTBP4,FAM135A,ANK2,PHF12,LGR5,ARNTL,LINC00173,PCDHGB4,NUMB,N4BP2L1,BACH1,JAZF1,LURAP1,SPAG9,CBLN1,CBFA2T2,DCLK1,CACNA2D2,LHX2,EPS15L1,NRXN3,PPT2,TPP1,WHRN,SMARCAL1,CPS1,CRYBB1,CSF1R,ARHGEF10,OSBPL3,PLXNA4,HDAC9,KATNAL2,TCAF1,EXOG,CPEB2,DTNB,DUSP9,EDN1,PHC2,EGFR,TNK2,COQ7,GPHN,CDKL3,PIPOX,STRADA,FDFT1,FGF1,FLYWCH1,GABRA3,IP6K3,TUBA8,GGT7,RUNDC3A,HPGDS,TDRKH,CCDC184,SERP2,RNF165,UBE2QL1,ZDHHC15,LRRC75A,ZNF678,ADAM11,PTOV1,FXYD7,NTRK3,IGSF11,CLDN11,P2RX7,PCDHGC3,PKM,PURG,EPB41L4B,POLG,MAPK4,MAPK9,HYDIN,WBP1L,CNTLN,ELOVL2,PTPRO,RAD51D,FAM66C,RDX,GTDC1,SLC25A36,SETD5,SPIN3,ADAL,TCP11L1,ATAT1,PPM1E,FBXO11,FHOD3,PPP4R3A,PKNOX2,SEPHS1,SIRT2,ELMO2,INAVA,TMCC1,FNBP1,MYCBP2,SPTAN1,TSPYL2,ATP10B,PBLD,TROVE2,NXT2,SEPT8,VPS13A,ANKRD28,TACR1,MTCL1,FBXW11,TCF4,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SIK3,C18orf54,CDH22,MTMR14,SYNPO2,VSNL1,MICU3,ZNF32,SMARCAD1,CADM2,GAL3ST3,PDSS2,ST7,TIGD6" MicroRNA hsa-miR-142-3p:mirSVR_highEffct hsa-miR-142-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.33E-60 1.86E-56 1.68E-59 1.55E-58 145 773 "KCNH8,FMNL2,MTUS1,OSBPL8,TAOK1,CEP126,LTBP4,EP400,MAP4K3,APC,ZFYVE28,ARNTL,INSYN2B,ATP2A2,DPY19L3,BACH1,PROM1,RAB29,L3MBTL4,CFL2,TMEM184B,SRP14-AS1,HECTD1,AKAP6,MYRIP,LRRC3B,ARHGEF10,PUM1,USP6NL,GAPVD1,ZFYVE16,EARS2,BRINP1,USP3,NR1D2,CPEB2,DMTF1,DPYSL2,ECM2,E2F5,WDPCP,ANKRD46,CNNM1,SEMA3D,CALCRL,RCAN2,CEP85L,ACSL4,CEP78,SUCO,FOXF2,FLNC,SLC37A3,HVCN1,ST6GALNAC3,FYB1,ACSS1,GHR,HPGDS,DIDO1,RNF165,KAT7,BVES,PSIP1,VSIG4,ZDHHC15,FAM95B1,LRRCC1,IL6ST,ITPKB,KCNN2,HECTD2,LRP1B,SRSF12,MGAT3,MMP16,MYO7A,P2RY13,NCAM2,NF1,SLC11A2,GPR137C,PAX6,PCSK1,PDE4B,ABCB1,FAM218A,ZFYVE21,STRN3,PRKAB2,OXR1,FIGN,RGS3,NUDT11,EXD2,ELP2,PCMTD2,RPE,LRRK2,SEMA6D,SCN8A,SUPT20H,SCAF8,SGK1,FNDC3A,CCDC88A,ELMO2,BTBD7,ATF7IP,MBD5,USP33,DOP1A,TSNAXIP1,KDM4C,TEX2,MCF2L2,SPART,NKAIN2,STAU1,DIP2A,NSFL1C,PLCB1,SYN2,SYPL1,MTCL1,ADGRL3,DMXL2,ZFP90,OBSL1,BHLHB9,ERCC6L2,TPM1,RUNDC3B,TSC1,UGT8,MTCH1,RICTOR,XPO1,TRIM9,MKRN3,STOX2,NAV3,PDSS2,FBXO36,KLHDC1" MicroRNA hsa-miR-187*:mirSVR_highEffct hsa-miR-187*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.44E-60 1.93E-56 1.74E-59 1.60E-58 151 839 "RALGAPA1,CLK4,NCKAP5,AXIN2,KIAA1211,BEND6,INTS2,RTL9,SPOP,BBOX1,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,SEMA4G,IGDCC4,RGS20,ASPA,SLC4A4,ATP6V1G2,BLM,SCAPER,DDR1,CALB1,SYNGR3,C1orf52,CDH2,DCLK1,NUMBL,CFL2,CHGB,CHN1,NDST3,NRXN3,ABCG2,MAP4K4,C2CD2,CREM,CRHBP,SIPA1L1,SOCS5,PLXNA4,SLITRK5,ERC2,PUM1,CCDC144A,MAML1,SACS,SPOCK3,CHRDL1,DYNC1I1,CASP8AP2,RCAN1,GOLT1B,PHC2,TMTC1,YAF2,FAM13A,PLEKHA1,C8orf37,EPHB1,DENND4A,ANKMY1,FAM198B,TMEM132C,FCGR3A,GTF2IRD2,FGF14,UBE2E3,MEX3B,SYNCRIP,ANKFY1,NBEA,USP21,SARAF,RNPS1,GNAO1,FUT10,GRIA2,FAM19A2,ZBTB49,PSIP1,IRAK3,RASSF8,MIER3,AGBL5,MSL1,RBPJ,INSM1,MARK1,ADAM22,CNOT4,PCDH9,PFKFB2,OLA1,PLCL1,MAPKAP1,SCHIP1,CNTLN,PTK2,ZIK1,KHDRBS2,RFX3,RGS4,SLC25A36,ALG9,RORB,STK32B,ATAT1,AP1AR,SAFB,ATXN2,FNIP1,HES6,SMPD3,FBXO11,BTBD3,SEPHS1,CPEB4,ZFP1,SNAP25,TMCC1,MYO16,BDP1,FNBP1,SP4,ZBTB43,MCF2L2,LMO3,ST5,SZT2,FRYL,CCDC173,DICER1,AP4E1,TMPO,KAT6B,TP53BP2,SYNPO2,RPL7L1,OSBP2,ZNF19,TRIM9,LYPD6,FSTL5,CADM2,FZD3,UBE3B,HNRNPA3,NLRP3,SENP7" MicroRNA hsa-miR-449a:mirSVR_highEffct hsa-miR-449a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.51E-60 1.96E-56 1.77E-59 1.63E-58 155 884 "SYS1,KDM5D,ADD2,ADRA1D,MTUS1,HACE1,KIAA1324,ALCAM,DOC2A,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,VAT1L,TNRC6C,TMEFF1,CADPS,NCOA1,DPY19L3,ADAM23,BCS1L,NRP2,SYNJ2,ARHGEF7,JAZF1,WASF1,CALB1,KALRN,DGKI,ZMYM4,EVI5L,TIGD7,NUMBL,CHN1,EPS15L1,RAB33A,SULT4A1,HECTD1,AKAP6,MYRIP,PREPL,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,PNPLA8,ZSCAN23,ZFYVE16,IST1,DGKB,BRINP1,ELMSAN1,RHOBTB1,RCAN1,DNM1L,E2F5,OPTN,KMT5B,RGS17,TMEM35A,C8orf37,EIF1,SPEG,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,PSD2,SLC37A3,NOP56,GABRA3,GHDC,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,CCDC184,PCLO,NXPH3,ARHGAP36,ITPKB,KCND1,KCNK3,KCNN2,KIT,HECTD2,CLEC18A,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,NTRK3,CDK18,GPR85,GNG2,JAKMIP1,PURG,STRN3,ING3,PKIA,MTMR10,PTPRD,EML5,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,OXR1,GTDC1,RIC8B,RNASEL,ZFHX4,SPIN3,TCP11L1,SATB1,ATXN7,KDM4D,DMRTC1,IFT122,KIF13A,SNRPN,PDZRN3,CLASP2,POGZ,ARHGEF9,SYT1,CAMTA1,FAM208A,ATMIN,SATB2,DOCK9,USP32P1,FRYL,RNF216P1,LRRC8A,TSN,TUBB1,PLEKHH2,BCL2L13,ZNF189,EMSY,CADM2,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-449b:mirSVR_highEffct hsa-miR-449b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.51E-60 1.96E-56 1.77E-59 1.63E-58 155 884 "SYS1,KDM5D,ADD2,ADRA1D,MTUS1,HACE1,KIAA1324,ALCAM,DOC2A,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,VAT1L,TNRC6C,TMEFF1,CADPS,NCOA1,DPY19L3,ADAM23,BCS1L,NRP2,SYNJ2,ARHGEF7,JAZF1,WASF1,CALB1,KALRN,DGKI,ZMYM4,EVI5L,TIGD7,NUMBL,CHN1,EPS15L1,RAB33A,SULT4A1,HECTD1,AKAP6,MYRIP,PREPL,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,PNPLA8,ZSCAN23,ZFYVE16,IST1,DGKB,BRINP1,ELMSAN1,RHOBTB1,RCAN1,DNM1L,E2F5,OPTN,KMT5B,RGS17,TMEM35A,C8orf37,EIF1,SPEG,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,PSD2,SLC37A3,NOP56,GABRA3,GHDC,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,CCDC184,PCLO,NXPH3,ARHGAP36,ITPKB,KCND1,KCNK3,KCNN2,KIT,HECTD2,CLEC18A,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,NTRK3,CDK18,GPR85,GNG2,JAKMIP1,PURG,STRN3,ING3,PKIA,MTMR10,PTPRD,EML5,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,OXR1,GTDC1,RIC8B,RNASEL,ZFHX4,SPIN3,TCP11L1,SATB1,ATXN7,KDM4D,DMRTC1,IFT122,KIF13A,SNRPN,PDZRN3,CLASP2,POGZ,ARHGEF9,SYT1,CAMTA1,FAM208A,ATMIN,SATB2,DOCK9,USP32P1,FRYL,RNF216P1,LRRC8A,TSN,TUBB1,PLEKHH2,BCL2L13,ZNF189,EMSY,CADM2,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-449a:TargetScan hsa-miR-449a TargetScan 3.56E-60 1.99E-56 1.79E-59 1.65E-58 123 549 "ABR,ADCY5,CCDC85A,ADD2,PTCHD1,MTUS1,HECW2,KCTD16,ALCAM,PITPNM2,ANK2,PKP4,NCOA1,CACNA2D1,DGKI,EVI5L,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,MAP4K4,RTTN,MYRIP,CLOCK,CSF1R,CNTNAP2,PPP1R16B,FAM131B,MYADM,LIN54,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,ACSL4,SCML2,AGAP2,FUT9,GABRA3,GHDC,INPP5K,CPLX2,LOXL3,GNAO1,GPR12,FRMD5,ARHGAP36,HNF4G,IL6R,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,PDE3A,PDE4B,GPR85,SDK2,PRKACB,PKIA,RELN,PTPRD,EML5,FAT4,RAP1GDS1,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,SATB1,ATXN7,SCN2B,GALNT10,MRAS,MYO18A,FAM81A,EPN2,CCDC88A,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,FAM208A,ATMIN,SATB2,NSD1,CRTC1,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,NAV3,RGS7BP,MARCH8,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-34c-5p:TargetScan hsa-miR-34c-5p TargetScan 3.56E-60 1.99E-56 1.79E-59 1.65E-58 123 549 "ABR,ADCY5,CCDC85A,ADD2,PTCHD1,MTUS1,HECW2,KCTD16,ALCAM,PITPNM2,ANK2,PKP4,NCOA1,CACNA2D1,DGKI,EVI5L,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,MAP4K4,RTTN,MYRIP,CLOCK,CSF1R,CNTNAP2,PPP1R16B,FAM131B,MYADM,LIN54,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,ACSL4,SCML2,AGAP2,FUT9,GABRA3,GHDC,INPP5K,CPLX2,LOXL3,GNAO1,GPR12,FRMD5,ARHGAP36,HNF4G,IL6R,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,PDE3A,PDE4B,GPR85,SDK2,PRKACB,PKIA,RELN,PTPRD,EML5,FAT4,RAP1GDS1,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,SATB1,ATXN7,SCN2B,GALNT10,MRAS,MYO18A,FAM81A,EPN2,CCDC88A,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,FAM208A,ATMIN,SATB2,NSD1,CRTC1,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,NAV3,RGS7BP,MARCH8,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-34a-5p:TargetScan hsa-miR-34a-5p TargetScan 3.56E-60 1.99E-56 1.79E-59 1.65E-58 123 549 "ABR,ADCY5,CCDC85A,ADD2,PTCHD1,MTUS1,HECW2,KCTD16,ALCAM,PITPNM2,ANK2,PKP4,NCOA1,CACNA2D1,DGKI,EVI5L,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,MAP4K4,RTTN,MYRIP,CLOCK,CSF1R,CNTNAP2,PPP1R16B,FAM131B,MYADM,LIN54,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,ACSL4,SCML2,AGAP2,FUT9,GABRA3,GHDC,INPP5K,CPLX2,LOXL3,GNAO1,GPR12,FRMD5,ARHGAP36,HNF4G,IL6R,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,PDE3A,PDE4B,GPR85,SDK2,PRKACB,PKIA,RELN,PTPRD,EML5,FAT4,RAP1GDS1,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,SATB1,ATXN7,SCN2B,GALNT10,MRAS,MYO18A,FAM81A,EPN2,CCDC88A,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,FAM208A,ATMIN,SATB2,NSD1,CRTC1,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,NAV3,RGS7BP,MARCH8,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-449b-5p:TargetScan hsa-miR-449b-5p TargetScan 3.56E-60 1.99E-56 1.79E-59 1.65E-58 123 549 "ABR,ADCY5,CCDC85A,ADD2,PTCHD1,MTUS1,HECW2,KCTD16,ALCAM,PITPNM2,ANK2,PKP4,NCOA1,CACNA2D1,DGKI,EVI5L,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,MAP4K4,RTTN,MYRIP,CLOCK,CSF1R,CNTNAP2,PPP1R16B,FAM131B,MYADM,LIN54,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,ACSL4,SCML2,AGAP2,FUT9,GABRA3,GHDC,INPP5K,CPLX2,LOXL3,GNAO1,GPR12,FRMD5,ARHGAP36,HNF4G,IL6R,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,PDE3A,PDE4B,GPR85,SDK2,PRKACB,PKIA,RELN,PTPRD,EML5,FAT4,RAP1GDS1,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,SATB1,ATXN7,SCN2B,GALNT10,MRAS,MYO18A,FAM81A,EPN2,CCDC88A,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,FAM208A,ATMIN,SATB2,NSD1,CRTC1,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,NAV3,RGS7BP,MARCH8,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-1274b:mirSVR_lowEffct hsa-miR-1274b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.61E-60 2.02E-56 1.81E-59 1.67E-58 175 1120 "KDM5D,MTUS1,RTL9,AK2,SYT13,AMPD2,SUGT1P4-STRA6LP-CCDC180,CDK10,SPTBN4,ARHGDIG,PLA2G4C,RASL11B,ADAM23,SGCE,CAMK2B,SPAG9,CERS5,SOCS6,PLEKHB1,NRXN3,FAM189A2,COL4A5,AKAP5,ABI3BP,COX4I1,AHCTF1,RTTN,RBM39,NCOR1,NCOR2,SNCAIP,CSNK1G3,VAC14-AS1,UBXN2A,ARHGAP32,ZFYVE16,AIF1L,ARMCX4,ZC3H11A,SV2B,SGSM2,DOCK2,DNAJB6,FCF1,CNNM1,FAM13A,EGFR,EGR3,TMEM35A,VPS13B,EPB41L2,DENND4A,CDKL3,MRPL10,FAM198B,ST3GAL6,PPP1R1B,FER,FGF1,FGF12,BAIAP2,JKAMP,STAU2,TUBGCP4,LUZP2,LPAR4,DIDO1,PLCD4,BACH2,SYNPO,ZDHHC15,KIAA1755,SCIN,SLC6A17,SLC35G1,KCNN2,CREG2,L1CAM,LAMP2,LIMS1,HECTD2,MAN2A2,ZFYVE27,MAP4,MBD1,MBP,CHIC1,XRRA1,MYO9A,NCAM2,NELL2,ALDH1L2,NFIX,NOVA1,IGSF11,PCDH9,CYTL1,ZNF655,PNMA3,MAPKAP1,LRP12,ING3,RETREG2,POLR2F,PPM1B,PPP2R2C,EPDR1,VPS13C,BDNF-AS,PTK2,PTN,TMEM260,PTPRG,ZSCAN2,CCDC40,RAD51D,SH3TC2,GTDC1,RGS4,EXD2,GSTCD,KIRREL1,RPE,MCMBP,TCP11L1,LRRK2,TNFRSF19,ASAP3,FUZ,AMBRA1,FAM81A,PPP4R3A,FAM214B,KANSL3,ELMO2,SNAP25,KIF13A,PDZD2,NMNAT2,GLT8D1,KDM4C,TSPYL2,CAMTA2,NKAIN2,ERBIN,SEPT3,PRRC2C,TACC1,ADGRL3,TBCEL,TBL1X,ATMIN,SATB2,TNS2,HIF3A,AP4E1,CSMD1,UBE2H,WIPF1,XRCC4,ZFP37,ZNF711,ZNF19,ZNF154,ZNF213,EMSY,LINC02210,STOX2,TUBA1A,PHTF2,CASC15,SNX14,IFT88,RNF146,LAS1L" MicroRNA "TGCTGCT,MIR-15B:MSigDB" "TGCTGCT,MIR-15B:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA "TGCTGCT,MIR-195:MSigDB" "TGCTGCT,MIR-195:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA "TGCTGCT,MIR-424:MSigDB" "TGCTGCT,MIR-424:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA "TGCTGCT,MIR-497:MSigDB" "TGCTGCT,MIR-497:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA "TGCTGCT,MIR-15A:MSigDB" "TGCTGCT,MIR-15A:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA "TGCTGCT,MIR-16:MSigDB" "TGCTGCT,MIR-16:MSigDB" MSigDB 4.20E-60 2.35E-56 2.10E-59 1.93E-58 125 569 "AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,ARHGDIA,STK33,ZBTB10,CHRD,SLC4A4,ATP2B2,ADGRB1,NRP2,SYNJ1,CALM1,KALRN,CAPN3,RUNX1T1,DCLK1,SRSF11,SOCS6,QKI,TBPL1,CLOCK,LRIG1,KCTD8,ARMCX2,POM121,DYNC1I1,CPEB2,DMTF1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,RASL12,EYA1,EZH1,ACSL4,SPSB4,SUCO,PDLIM5,NSG1,TPPP3,GABBR1,SESN1,PCDH17,GHR,FERMT2,TMEM121B,CLASRP,HAS2,ZHX1,BACH2,KIF5A,SFXN5,MAP4,MBD1,LRP1B,ZC3H12B,PCDH9,PIK3R1,RETREG2,EPB41L4B,FSD1,LRRN3,RASGEF1B,MAPK3,RELN,DEF8,SNRK,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SEMA6D,ATXN2,MRAS,HSPA4L,SGK1,KIF21A,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,KBTBD4,SLC12A2,ELMO2,TMCC1,ZHX3,TSPYL2,STX1A,STXBP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TRPM2,HIRA,WNT7A,KLC2,RICTOR,ZIC1,STOX2,KCNAB1,PCBP4,ADAMTSL3" MicroRNA hsa-miR-425:mirSVR_highEffct hsa-miR-425:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.92E-60 3.31E-56 2.95E-59 2.71E-58 154 876 "NCKAP5,ADCY6,BRAP,ZNF608,KLHL13,CC2D2A,AMPH,LCORL,BCAS1,ATP1B3,N4BP2L1,ADGRB3,MPDZ,BTK,SGCE,C5,KALRN,HIP1R,SPAG9,CFL2,SRSF11,B4GALT6,QKI,CNN3,ARHGEF6,ARMC8,WHRN,MYRIP,ZFP28,CLOCK,CREM,RBM39,CS,LRIG1,PHACTR3,GREB1,CYBB,DOCK4,GPRASP1,RIPOR2,DGKG,KIAA0319,RHOBTB1,SNAP91,SV2B,EXOG,CDON,CPEB2,GOLT1B,EDIL3,EDNRA,KMT5B,PCOLCE2,DNAJC27,SH3YL1,ZSCAN30,GTF2IRD2,SUCO,SYNCRIP,ANKFY1,GABRB3,GAD1,GALC,KIAA1841,COPS8,WDFY3-AS2,PCLO,ATP2B1-AS1,RNF165,ARHGAP36,ELOVL5,HNMT,SHISA6,IGF1,ZNF678,ITPKB,SLC35G1,STXBP5,STMN1,MARK1,MBD1,LRP1B,MEF2C,MEIS1,MIA2,PPM1L,GIT1,MSR1,ZNF862,NCF2,CNOT4,NTRK3,NUCB2,OCRL,PRTG,PLCB2,PLCL1,PURG,TRHDE,ING3,MINDY2,MAPK9,QRICH1,CNTLN,PTCH1,BDNF-AS,PTPRN2,ZNF844,RGS4,MRPS18A,NUDT11,SETD5,RPL15,FBXW7,BAALC,LRRK2,GALNT10,PPM1E,CHD9,PPP4R3A,SLC6A11,LIMCH1,SNAP25,MBD5,SNRPN,PDZRN3,ZNF423,ZC3H13,CLSTN2,SSTR2,NKAIN2,NXT2,CEP68,VPS13A,SYN2,SATB2,RPGRIP1L,DICER1,BHLHB9,BEX4,TNS1,TRO,STXBP4,TSN,VLDLR,WIPF1,KCNT2,EML6,PRDM8,PARP11,KAT6A,ADAMTSL3,IFT88,FAM198A" MicroRNA hsa-miR-620:mirSVR_highEffct hsa-miR-620:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.21E-60 4.03E-56 3.59E-59 3.30E-58 163 981 "PWWP2A,HECW2,CC2D2A,TAOK1,BBOX1,FAM135A,OGT,APAF1,STK33,CCDC74A,ATP1B3,STX16,N4BP2L1,ATP6V1G2,ADGRB3,CACNA1B,LURAP1,THSD7A,KALRN,LRBA,ARHGEF2,MAGI1,UBE2L6,RCBTB2,NDST3,LHX2,PCYT1B,SLC35F1,CS,VCAN,ZSCAN23,HDAC9,EARS2,IST1,DAPK1,PITPNC1,ARMCX2,YTHDC1,ELMO1,RHOBTB1,ZNF582-AS1,CPEB2,DTNA,AASDH,EDIL3,CNNM1,YAF2,CELSR3,PHF20L1,APH1A,MBNL2,GOLGA7,COPS4,RGS17,TMEM35A,EPHB1,PIPOX,F8,CLVS1,FAM198B,FCGR1A,CEP78,MED12L,FGF13,FGFR1,SPECC1,APOPT1,KHDRBS3,FYB1,GABBR1,GGT5,PPARGC1A,MALT1,GLI2,GLYR1,ZNF638,GPR12,MCHR1,ZNF496,FAM19A2,RASSF8,HMGCL,AGBL5,SHISA6,CELF5,IRF8,ZIC5,LRRCC1,FAM69A,NME9,JAK2,KCNJ5,MSR1,MYO7A,NFE2L2,NTRK2,P2RY1,GLIPR1L2,CNTN3,PRTG,OLA1,STRN3,NECAB2,EPB41L4B,PRKACB,HYDIN,VPS13C,WDR25,PIGG,BDNF-AS,TMEM260,PTPRD,CASTOR1,PTPRG,PTPRO,C1orf109,HKR1,GTDC1,TMLHE,MEG3,SCP2,COPZ1,ZFP30,SHC4,NUBPL,SLC12A4,SLC22A4,LIMCH1,SNRPN,MYO16,PDZD2,HECW1,KDM4C,RBM26,LMO3,CLSTN2,NXT2,STAU1,NUDT10,PLCB1,FAM208A,FBXW11,TRIM2,TCF12,SYNE1,FAM189A1,DICER1,C18orf54,AP4E1,BEX4,TPM1,TTTY15,UGT8,OSBP2,USP1,TRIM9,NAV3,EPM2A,ST7,PHTF2,RNF170,KLHDC1,GAN" MicroRNA hsa-miR-183:mirSVR_highEffct hsa-miR-183:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.53E-60 4.21E-56 3.75E-59 3.45E-58 152 855 "NCKAP5,OSBPL8,TXNDC16,ARHGAP20,OGT,PKP4,UPRT,LINC00173,SCAPER,RUNX1T1,TIGD7,SRSF11,CNOT8,RAB28,CLCN3,QKI,AKAP5,RTTN,CNRIP1,AKAP12,HAPLN1,CS,CSF1R,ARHGEF10,CCDC144A,BOC,RIPOR2,ZFYVE16,DBI,ARMCX4,RHOBTB1,SACS,DYNC1I1,DTNA,FAM78B,FARSB,TSPAN5,YAF2,PHF20L1,SUGP2,TLR7,F8,CLVS1,ABCA8,FAM198B,GORAB,TMEM164,SUCO,SCARA3,AGAP3,SEMA4D,UFM1,TRIM16,RASL10A,ATP2C1,CELF1,HRASLS5,TUBA8,SESN1,LYVE1,GLUL,KDM2B,GNAO1,FERMT2,GPR34,PRDM5,USP51,ICA1,KCND2,KIF2A,HECTD2,MBNL1,MEF2C,SRSF12,AFDN,IDNK,DNHD1,NRCAM,P2RX7,GPR85,GNG2,PFKFB2,PIK3R1,XRN1,ING3,EPB41L4B,PPP2R5E,PRKACB,MAPK4,MAPK9,GRAMD1C,HYDIN,MTMR10,TMEM260,EML5,PTPRE,PTPRG,ACSM5,PPP2R3C,RASGRF2,RBBP6,KHDRBS2,ROBO2,ELP2,CLIP1,AP1AR,SCP2,KIF21A,MTERF2,TET1,RCOR3,TTC17,SNRPN,PDZRN3,NFASC,LMO3,ATP10B,POGZ,ERBIN,DIP2A,ADHFE1,SYN2,SLC37A2,TCF4,ZEB1,TCF12,FRYL,ZFPM2,SLC44A1,TIMP4,ACTR6,TMPO,BEX4,RIMBP2,TPM1,SYNPO2,VLDLR,WRN,CLDND1,LGI4,ATP6V0E2,ZFAND5,DNALI1,TMEM178A,GAL3ST3,TRIM16L,PLSCR4,FAM13C,FZD3,SMIM8,ZDHHC20,FRMD6" MicroRNA hsa-miR-660:mirSVR_lowEffct hsa-miR-660:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.77E-60 4.35E-56 3.86E-59 3.56E-58 187 1276 "KCNH8,CLK4,NCKAP5,NDRG3,KLHL32,PTCHD1,BEND6,AP2A2,MTUS1,KCTD16,KIAA1324,AK2,C1QTNF3,ABCD2,MARCH4,SYT13,OGT,PPFIA4,APC,VAT1L,ARNTL,MARCH3,STX16,N4BP2L1,ADGRB2,DNAJC27-AS1,ARHGEF7,NAE1,SCAPER,CALM1,KALRN,PRC1,SCARB1,LRBA,DCLK1,TIGD7,CNOT8,FAM19A5,RAB26,ARHGEF6,IQCK,AKAP6,LETMD1,SLC4A8,ABI3BP,TOGARAM2,SEC24C,CSNK1G3,DZIP3,APPL1,PLCXD3,GPSM1,CYBB,GAPVD1,DCAF8,HEPH,RHOBTB1,SNAP91,DMD,ECM2,E2F5,AASDH,EDNRA,EDNRB,FRY,GOLGA7,EIF4G2,TENM1,USPL1,EIF1,TUBD1,COQ7,RCAN2,LRRC17,ERBB2,CEP85L,ZNF549,CDKL3,CLVS1,ABCA8,CORO2B,DLC1,CHST15,POLK,SUCO,SYNCRIP,FLT1,NELFCD,TMEM107,RASL10A,ERGIC3,KHDRBS3,DOT1L,OGA,DENND2A,FAM120B,GFRA2,RAB30,MSL3,ZNF638,HTATSF1,LUZP2,GPD2,BVES,HAS2,AGBL5,CELF5,LRRC25,RBPJ,ZNF678,KCND1,LAMP2,LIFR,HECTD2,SMAD1,GPR155,MEIS1,AFF1,PTOV1,HS6ST3,MYO7A,MYO9A,NCAM2,NPTX1,SLC11A2,NTRK2,CHAMP1,P2RX7,ETFRF1,ING3,POLR2F,PRKAB2,PRKACB,GRAMD1C,MASP1,BCAS3,VPS13C,SNRK,TMEM260,PTPRE,ACSS3,RADX,RDX,TRIM68,ERI2,RIC8B,PBRM1,LGI2,CCDC102B,ABCA11P,HUNK,CLIP1,ZNF568,SCN8A,TNFRSF19,MRAS,SGK1,CPEB3,NUBPL,CCDC88A,ANKRD36,MAPKBP1,SNCA,DOP1A,ZC3H13,RBM26,CLSTN2,POGZ,ADHFE1,KANK1,SYNE2,NEU4,ZEB1,TRIM2,CLASP1,TEK,AP4E1,SLC44A1,TMPO,UBE2H,RICTOR,XPO1,ZNF24,TRIM9,ANKS1B,GDPD5,SIGLEC10" MicroRNA hsa-miR-1911:mirSVR_lowEffct hsa-miR-1911:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.08E-60 5.08E-56 4.51E-59 4.15E-58 144 768 "ACTN1,AXIN2,PLEKHH1,ESYT2,BBOX1,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,CDK10,IGDCC4,EIF4G3,RNF182,DOCK11,TTLL9,DST,PTBP2,CDH2,CHN2,CNN3,CREM,PDE4DIP,KIAA0040,DCAF8,MATR3,ALKBH8,CHRDL1,DYNC1I1,DNAJB6,ABCC5,DNM1L,EBF1,HIPK3,TMTC1,YAF2,C8orf37,DCTN4,EIF1,SRRM1,FCGR1A,ZSCAN30,ZNF589,FGF13,POLK,SEC23B,FOXO3,ST6GALNAC3,STAU2,DENND2A,MTHFD2,DISC1,GCNT2,ARFIP1,PPARGC1A,CRCP,GNG4,GPR34,PLCD4,CIT,BVES,PSIP1,ARHGAP36,ELOVL5,HSF2,FAM95B1,HECTD2,ASPRV1,ZFYVE27,TM6SF1,KCTD6,MID1,ADAM22,ZC3H12B,NFE2L2,NTRK2,OPA1,PCDH8,PCDH9,CYTL1,OLA1,FAM216A,PLCL1,STRN3,ING3,PPM1B,PPP2R2C,VSTM2L,CNTLN,MTMR10,PTPRN2,ACSM5,CEP97,USP47,FAM184A,RBBP8,SLC25A36,RIC8B,ZNF532,RORB,ELP2,PCMTD2,MRAP2,ADAL,PTGR2,HSD11B1L,ATXN2,SCP2,ARX,HKDC1,FBXO11,FAM214B,ARHGEF40,SMARCA4,TTC17,ANKRD36,TMCC1,SP4,RBM26,NKAIN2,NEK4,SULF2,PJA1,CLASP1,PCDHB3,FAM200B,SIRT1,AKTIP,SLC44A1,NR2E1,RGMB,ZNF346,PDSS1,PPIL6,SGK3,WIPF1,KCNT2,REEP1,ZFAND5,MFF,HPS4,VPS35L,FAM47E,PDSS2,DOCK8,ADAMTSL3" MicroRNA hsa-miR-3170:mirSVR_highEffct hsa-miR-3170:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.97E-60 5.58E-56 4.94E-59 4.55E-58 153 868 "ABHD6,PLEKHH1,OSBPL1A,CC2D2A,MYH7B,AQP6,INSYN2B,N4BP2L1,CAMK2G,RUNX1T1,DGKI,ZMYM4,TIGD7,CFL2,SRSF11,CPNE6,NRXN3,TPP1,MYL6B,FAM19A5,QKI,CNGA3,CNR1,COL9A1,ZNF521,SLC35F1,SEC31B,HINFP,C1QL2,GDA,CLIP3,CSF2RA,PLXNA4,APPL1,RIMS2,RUBCN,CYBB,TCAF1,ARMCX4,HEPH,RHOBTB1,SNAP91,SV2B,CHRDL1,DLX1,DMD,DMPK,GOLT1B,AASDH,EDNRA,PHF20L1,MBNL2,EMX2,IGSF6,ETV1,F8,ABCA8,ST3GAL6,GORAB,FGF13,FGFR1,TMEM164,MEX3B,HPCAL4,TMEM107,STAU2,GABRA3,DISC1,ADAM28,PCDH17,CRCP,DBF4,TNRC6A,GLUL,GRIA2,SPACA9,GRIK5,BVES,RNFT2,HMGCL,SMAP1,LRRC25,TJAP1,IL6R,LRRTM1,KIF5A,LAMA2,POC1B,IDNK,NF1,NFIX,VWA2,CNOT4,PCSK5,TMEM38A,PURG,PMP22,TATDN3,PKIA,MAPK3,GDPD1,MASP1,SNRK,PID1,TMEM255A,OXR1,ZMAT4,UBR7,RNASEL,CCDC82,CARF,YY1AP1,ATP8B4,ATAT1,SEMA6D,TNFRSF19,ARX,SHC4,FHOD3,FAM81A,DHX30,SLC8A1,CCDC88A,SLC14A1,ATF7IP,PDZD2,TSPYL2,PBLD,SEPT8,SULF2,NECAB1,SYN1,MLST8,TCF4,PCDHB15,TNS2,CCDC173,ZMAT3,SLC44A1,ARL10,TIMP4,IL34,SLC35A4,PLEKHH2,ZNF709,BCL2L13,NDRG4,ZNF138,ZBTB38,EMSY,SIGLEC10,FAM13C,RNF170" MicroRNA hsa-miR-362-5p:mirSVR_highEffct hsa-miR-362-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-59 5.83E-56 5.16E-59 4.75E-58 143 758 "SYS1,AP2A2,ATP1B3,ADAM23,LINC00847,CFLAR,CASTOR3,CALB2,CAMK2B,CAST,CCNH,USP6,LRBA,CLGN,COPB2,NRXN3,TPP1,AKAP6,RBM39,RNF14,UBXN2A,ZFYVE16,KIAA0586,PITPNC1,KIAA0753,DDX46,DNM1,USP3,CASP8AP2,ACOT8,PDCD6IP,WDPCP,SEMA3D,KLHL5,APH1A,CEP85L,ADGRV1,F8,CLVS1,TAOK3,CORO2B,SEC23B,PDLIM5,ZNF605,CELF1,GALNT15,GABRG2,RAPGEF6,C15orf41,ADAM28,FREM1,TXNL4A,COPS8,DBF4,ZNF638,KDM2B,KCNMB4,GSTT2,MIER3,AGBL5,HNMT,USP51,SMAP1,IGF1,SCIN,JAK2,SLC35G1,KCNH2,MKLN1,MMP16,ADAM22,CNOT4,PCSK5,PDCD2,RETREG1,PLCD1,JAKMIP1,PRIMPOL,STRN3,PILRA,PPM1B,PRKACB,EPDR1,HYDIN,CNNM2,CNTLN,BDNF-AS,TMEM260,PTPRD,PTPRE,CEP97,REV3L,SLC25A36,SETD5,ARMC5,CCDC102B,RPE,BAALC,TCP11L1,ATAT1,RMI1,SATB1,CASC3,KIF21A,ST6GAL1,SEPHS1,NAPB,CXXC4,ANKRD36,MBD5,ZNF415,SNRPN,KDM4B,USP33,KDM4C,NKAIN2,ADHFE1,STXBP1,NUDT10,TACR1,MTCL1,ATMIN,TCEA1,FRYL,C18orf54,AP4E1,TLR4,NR2E1,ERCC6L2,CDK20,RUNDC3B,TUBB1,UGT8,ZNF709,PCDH20,MICU3,KCNT2,CELF4,SEMA3B,SLC17A7,FZD3,FBXO36,ADAMTSL3" MicroRNA hsa-miR-3164:mirSVR_highEffct hsa-miR-3164:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-59 6.61E-56 5.85E-59 5.38E-58 165 1008 "C3orf14,XKR4,FMNL2,TXNDC16,OGT,DPP10,MAP4K3,PHF12,PPP4R4,ARHGDIA,STK33,NUMB,SLC2A11,N4BP2L1,BACH1,MPDZ,SEC11C,PROM1,BMP7,DST,ARHGEF7,C5,PTBP2,RUNX1T1,ZNF501,SEPT7,MAGI1,C4orf33,FHL5,CNTFR,AKAP6,SLC4A8,FAM171B,CREM,RNF14,GALNT9,VCAN,SOCS5,PDE4DIP,ZSCAN23,TCAF1,YTHDC1,TIAM2,GRIN3A,DTNA,DNAJB6,GOLT1B,EDN3,EDNRB,RASGRP1,MBNL2,EGR3,STX2,IGSF6,ACSL4,FCGR1A,FGFR1,PRKAG2,PDLIM5,ZNF605,AP4B1,GABRA3,GAD1,ZNF559,SRCAP,GGT7,TXNL4A,KDM2B,TDRKH,LPAR4,GRM2,PRDM5,FAM19A2,AP4S1,RASSF8,UBE2QL1,INSYN1,ARHGAP36,ZDHHC15,IDH3A,IDH3B,LRRCC1,SLC35G1,KIF5A,LSS,MAT2A,MBNL1,MEIS2,MEST,AFDN,ZNF680,ZC3H12B,NF1,NPTX2,NRCAM,NUCB2,PCDH9,GPR85,SNX10,FAM216A,MINDY2,GRAMD1C,VPS13C,SNRK,TMEM260,STK32A,ZIK1,PEX2,QDPR,MARCH1,OXR1,RADX,GTDC1,FIGN,RGS4,TMLHE,ALG9,ROBO2,RPL15,SPIN3,ZC3H14,KIAA0895L,ATXN7,SCN7A,ARX,FBXO11,SEC31A,NUBPL,SLC11A1,CPEB4,SMARCC2,ANKRD36,SNCA,SNRPN,FNBP1,KDM4C,TEX2,SULF2,ZC3H4,MTCL1,MCF2L,DNMBP,ADGRL3,TCF4,TRIM2,PUM2,ZFPM2,ITGB3BP,RASD2,RGMB,HIRA,RPL7L1,GORASP1,PLEKHH2,MGAT5B,ZNF28,MKRN3,DNALI1,RNF103,ADAMTS9,SIGLEC10,SLC17A7,HNRNPA3,TRAM2-AS1,SNX14" MicroRNA hsa-miR-651:mirSVR_highEffct hsa-miR-651:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-59 8.74E-56 7.73E-59 7.12E-58 171 1082 "RALGAPA1,ACADM,BRAP,PLEKHH1,MTUS1,OSBPL1A,PCDH10,APBA2,ARNTL,ARRB2,SLC4A4,ZNF582,ADGRB3,BMPR1B,SYNJ1,THSD7A,CALM1,VXN,CAST,SEPT7,MAGI1,CFL2,SRSF11,LHX2,PLAA,CNTN1,ARMC8,FAM171B,CLOCK,ANKRD44,CLIP3,CSF1,ARHGEF10,CSNK1G3,PUM1,CYBB,LONRF1,DBI,GIT2,ELMO1,FBXL5,CHRDL1,EXOG,DMD,ARRDC4,DNM1L,EBF1,EDN1,EDNRB,ANKRD46,SEMA3D,PHF20L1,RGS17,STARD3NL,C8orf37,FKTN,ZSCAN30,GORAB,MED12L,SUCO,SEC23B,GATM,SULT1C4,SESN1,GHR,RAB30,CBX1,LNX1,GPR34,PCLO,ATP2B1-AS1,FAM19A2,PSIP1,DHX35,RBPJ,KIAA1755,SLC35G1,LMO2,HECTD2,MAP4,MBD1,PPM1L,AFDN,XRRA1,MXI1,MYCN,MYO7A,MYO9A,NFE2L2,CNOT4,NRCAM,NTRK2,LOC100128398,PDCD2,GPR85,ZNF655,FAM218A,GPSM2,MTRF1L,PMP22,TRHDE,PSAT1,PPP2R5E,PPP3CA,EPDR1,HYDIN,MASP1,VPS13C,PTPRB,EML5,PTPRG,MARCH1,CEP97,NWD1,ZDHHC14,ERI2,RFX3,CARF,ATP8B4,GLDN,MEG3,TRAPPC13,FAM192A,GALNT10,HKDC1,CNKSR2,SLC2A5,CCDC88A,SLC12A2,MTERF2,TET1,CPEB4,SNRPN,SOX3,KDM4C,SPART,CLASP2,SSTR1,STXBP1,PRRC2C,COBL,TACR1,SATB2,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,BEX4,C9orf85,SYNPO2,STXBP4,CLHC1,UBE2H,PLEKHH2,CCDC14,WIPF1,ZNF28,FSTL5,ANKS1B,SLC30A4,RNF103,ADAMTS9,NAV3,RGS7BP,FZD3,ADAMTSL3" MicroRNA hsa-miR-626:mirSVR_highEffct hsa-miR-626:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-59 1.34E-55 1.19E-58 1.09E-57 139 720 "VWA5B2,KCNH8,NCKAP5,NDRG3,FAHD2CP,WDR35,DPP10,MAGEE2,PHYHD1,STK33,DPY19L3,KSR1,CALB1,PTBP2,MAGI1,NDST3,NRXN3,ARHGEF6,CNR1,FAM149A,AKAP6,COL4A5,COL9A1,CNRIP1,C2CD2,ENTPD4,RBM39,ANKRD44,GDA,TRIM69,ABCG1,CSNK1G3,VCAN,UBXN2A,HDAC9,KIAA0586,DGKB,GIT2,HEPH,MYEF2,FBXL5,ZC3H11A,SLC25A18,DTNA,EBI3,PAN3,EPHB1,GPHN,DENND4A,CDKL3,EYA1,FAM198B,GTF2IRD2,FGF14,POLK,COQ5,WDR83,SPECC1,CAMKK2,CELF1,ST6GALNAC3,GABRG2,C15orf41,ARFIP1,GGTA1P,PPARGC1A,GPD2,LILRA2,MAP4K5,VSIG4,LRRC75A,IGF1,KNDC1,FAM69A,KCNB1,KCNJ16,KIF2A,STXBP5,NCOA7,SMAD9,MBNL1,MEIS2,MITF,XRRA1,MMP16,GLIPR1L2,DPY19L2P2,PCDH9,PDE4D,GNG2,PPM1B,KANSL1,PRPSAP2,SAMD9,CNTLN,TMEM260,PTPRG,RBBP6,SLC25A36,CARF,ZC3H14,ATP8B4,GLDN,ATAT1,SUPT20H,SYBU,FAM81A,FAM214B,SLC14A1,SLC22A4,ZFP1,IFT122,MYCBP2,ERBIN,SEPT8,PLCB1,SYT1,FBXW11,ZFP90,USP32P1,GPRIN3,TMPO,RGMB,PPIL6,UBE2H,BCL2L13,WIPF1,XRCC4,ZBTB14,ZBTB38,REEP1,EML6,FIP1L1,PARP11,PDSS2,PHTF2,FAM219B,RNF170,NETO1" MicroRNA hsa-miR-4302:mirSVR_highEffct hsa-miR-4302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-59 1.39E-55 1.22E-58 1.13E-57 143 763 "PLEKHH1,OSBPL8,CEP126,MAP4K3,APAF1,APOC1,PPP4R4,CADPS,SLC4A4,SLC2A11,ADAM23,TTLL9,BACH1,ZNF599,SCAPER,MTMR2,CA4,CA12,KALRN,PTBP2,CAST,MTMR7,P2RX6,LRBA,L3MBTL4,PLAA,FHL5,SLC4A8,ABI3BP,PREPL,CREM,CRY2,GDA,CS,SLITRK5,UBXN2A,PNPLA8,DCAF4,HDAC9,ARHGAP24,RASSF2,DAPK1,DDX46,RHOBTB1,DMD,NR1D2,DMTF1,EBF1,KMT5B,SIRPB1,CLVS1,PSD2,C2orf88,SMC2,TPK1,STAU2,AP4B1,GAD1,ZNF274,IQGAP2,ZNF559,ARFIP1,CYP46A1,GHR,MALT1,RUNDC3A,GNAO1,PRDM5,GUCY1B1,ARHGAP36,CFAP126,KCNK3,KIF5A,PAXBP1,HECTD2,MARK1,MAT2A,MEIS1,MEIS2,POC1B,NCF2,VWA2,GPR137C,PDE3A,FAM216A,PLCL1,PLXNB1,TRHDE,SEPT4,EPB41L4B,FA2H,MAPK4,MASP1,RELN,APTX,SNRK,MTMR10,PTPRG,ZNF844,CEP97,RASGRF1,GTDC1,RFX2,SLC25A36,RIC8B,ELP2,MRAP2,KIAA0895L,MEG3,KCNIP1,SATB1,SGK1,SH3GL3,SHC4,ST6GAL1,SEC31A,SLC6A11,SLC8A1,CXXC4,MBD5,DOP1A,MYCBP2,ATP10B,TROVE2,NKAIN2,SEPT3,STXBP1,SYT1,C12orf76,DNAH7,SLC44A1,AMACR,PRR18,ZKSCAN5,TUBB2A,ZNF610,ZNF781,SLC38A1,FAM13C,PHTF2,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-664*:mirSVR_highEffct hsa-miR-664*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-59 1.47E-55 1.30E-58 1.19E-57 159 943 "AS3MT,ADD1,KIAA1211,RNF150,AP2A2,AK2,APC,MARK4,TMEM108,ATP1B3,ATP2A2,BACH1,JAZF1,NFS1,CCNH,DGKI,SEPT7,MAGI1,TIGD7,CLGN,SOCS6,MS4A7,ARHGEF6,AKAP6,SLC4A8,ZFP28,ANKRD44,TRIM69,CSNK1E,ERC2,UBXN2A,PHF14,PNPLA8,PUM1,RIMS2,USP6NL,BOC,TBC1D5,IST1,DGKB,JAKMIP2,DGCR5,RAB39B,HS3ST2,RPS6KL1,DYNC1I1,DPYSL2,DTNB,KRBA2,SNX29,WDPCP,RASGRP1,PHF20L1,CALCRL,PAN3,SLC43A2,ZNF589,FGF12,FGF14,POLK,FOXF2,FLT1,ANKFY1,SMC2,CELF1,ZNF44,TRAF3IP2,DENND2A,KIAA1841,GCNT2,TUBGCP4,LUZP2,MAP4K5,ZHX1,FRMD5,GABARAPL2,HMGCR,HNMT,SMAP1,ITPKB,KCNN1,MAP4,MBNL1,MITF,N6AMT1,MYO7A,NF1,NFE2L2,ALDH1L2,SMIM11A,CHAMP1,CLDN11,PRTG,PDE1B,ZFYVE21,TMEM38A,ZNF426,ANKRD16,MINDY2,PRKACB,CNTLN,ACSM5,PPP2R3C,SLC25A48,CCDC40,RASGRF1,RGS3,LGI2,CARF,MCMBP,ATP8B4,FAM192A,ZFP30,FNDC3A,NLGN1,SLA,SLC14A1,RCOR3,ANKRD36,SOX3,ZSWIM8,SP4,TROVE2,POGZ,SS18,SYNE2,SYT1,MTCL1,ALG1,TBCEL,DMXL2,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,C18orf54,AP4E1,AKTIP,TMPO,SYNPO2,ELP5,CLHC1,SGK3,WIPF1,CLDND1,RICTOR,ZNF74,MKRN3,TCEAL7,INTS3,RGS7BP,TIGD6,GAN,SENP7" MicroRNA hsa-miR-1238:mirSVR_lowEffct hsa-miR-1238:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.82E-59 1.58E-55 1.39E-58 1.28E-57 168 1050 "SYS1,ACTN1,BEND6,WDR35,ALCAM,AMPH,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,APBB2,BCAS1,ZFYVE28,PLA2G4C,NCOA1,EIF4G3,ATP2A2,ATP2B2,N4BP2L1,SYNJ1,ST3GAL5,PTBP2,RUNX1T1,ENTPD6,CDO1,CCPG1,MS4A7,CLCN3,AKAP6,TBPL1,ZNF521,NRG2,CNRIP1,CREM,SIPA1L1,PITPNM3,GREB1,LIN54,IP6K1,YTHDC1,DDX46,CDON,DMTF1,DTNA,TOM1,E2F5,PHF20L1,MBNL2,STX2,SPEG,MRVI1,NSRP1,PRMT5,FER,FGF11,AMOTL2,ZMAT1,TRAF3IP2,RAPGEF6,C15orf41,ALDH1L1,NFU1,ADAM28,ZNF276,GLI2,TNRC6A,ZNF638,KIAA1958,DCLK2,LNX1,CCDC184,PCLO,STMN2,ADAMTS13,MAP4K5,UBE2QL1,ARHGAP36,AGBL5,IGF1,SCIN,IL6ST,IL12A,KCNN2,KPNA5,PAXBP1,MARK3,MBD1,MBNL1,LRP1B,MID1,FXYD7,IDNK,NEK1,NFE2L2,NME4,NUCB2,IGSF11,GLIPR1L2,PDE4D,SLC10A4,KCTD15,JAKMIP1,SEPT4,PPP2R5E,PKIA,PRKCB,DCHS2,MASP1,WBP1L,PTK2,PTN,PTPRE,PID1,RASGRF1,KHDRBS2,REV3L,ERI2,GTDC1,RGS12,EXD2,ROBO2,FBXW7,TCP11L1,HSD11B1L,PRCD,FOXRED1,RASA3,NLGN1,ANKRD6,CDK5RAP3,ELMO2,BTBD7,ZFP1,CDK5RAP2,SNRPN,TRERF1,MYCBP2,PEG10,SS18,EXOC7,PDLIM2,ZEB1,TCF12,SYNE1,PHF24,PCDHB3,USP32P1,GPRIN3,AP4E1,TIAM1,TMPO,TPM1,NPL,C9orf85,SMUG1,RUNDC3B,STXBP4,ZKSCAN5,EIF4ENIF1,ZIC2,CELF4,SMARCAD1,UPF3A,HRASLS,FAM13C,DOCK8,UBE3B,KAT6A,FXR1" MicroRNA hsa-miR-335:mirSVR_highEffct hsa-miR-335:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.85E-59 1.59E-55 1.40E-58 1.29E-57 154 886 "NCKAP5,CCDC85A,AP2A2,TXNDC16,APAF1,VAT1L,SHROOM2,CDC14B,CDK10,CDK13,STK33,ZBTB10,NCOA1,SCAPER,CA8,CERS5,CD38,LRBA,NDST3,RAB33A,NGEF,FBXO7,ARMC8,AKAP6,SLC4A8,AHCTF1,ZFP28,CNRIP1,SLC35F1,FAM171B,HINFP,OSBPL3,DZIP3,ERC2,CTH,ARHGEF4,FAM131B,DOCK4,DCAF8,LONRF1,DGKB,DAPK1,PABPC5,SPATA2,ZNF804A,KIAA0753,DDX46,FAM107B,ABCC5,EBF1,FSD1L,YAF2,PHF20L1,SUGP2,RASA4,VPS13B,EPB41,CEP85L,GORAB,FGF13,SUCO,FLT1,UFM1,CAMKK2,CELF1,STAU2,RAPGEF6,KIAA1841,GLYR1,KDM2B,RAB40B,PRUNE2,STMN2,KAT7,PSIP1,GUCY1A1,ZHX1,HMGCR,ZNF546,INPP1,KIT,LSS,MAP6,MAT2A,MBD1,TM6SF1,AFDN,NACA,HNRNPM,NF1,NTRK3,NUCB2,PCDH9,TMEM38A,PLIN1,PRIMPOL,EPB41L4B,PPP2R5E,RANBP3L,PRKCB,MAPK9,MAPK10,DIRAS2,APTX,PTPRH,FAM66C,RBBP6,ERI2,FIGN,RNASEL,ZFHX4,ZNF532,SETD5,ROBO1,ELP2,MAP6D1,PTGR2,SALL1,SUPT20H,TRA2B,SYBU,SEPHS1,SLC12A2,SNRPN,MYO16,ZSWIM8,KDM4C,ZBTB43,SSTR1,ZC4H2,STAU1,DNAJC9,PJA1,KLHL4,TCF4,SATB2,SIK3,ITGB3BP,AP4E1,TK2,FAM124A,SYNPO2,AMACR,RPRM,UBE2H,LGI4,PRDM10,VPS35L,PDSS2,RGS7BP,DNAH10,SMIM8,NHSL1,NETO2" MicroRNA hsa-miR-381-3p:TargetScan hsa-miR-381-3p TargetScan 3.01E-59 1.68E-55 1.48E-58 1.36E-57 128 608 "KIAA1211,HACE1,ARHGAP20,LRFN1,CDC42BPA,APC,CCAR2,EIF4G3,ATP2A2,DOCK11,NRP2,MAGI1,DLGAP2,NRXN3,FAM19A5,HECTD1,ABI3BP,CLOCK,AKAP12,CLIP3,OSBPL3,PLXNA4,APPL1,GREB1,KIAA0408,GAPVD1,ARHGAP24,FAM107B,GRIN3A,RAB39B,DMTF1,EBF1,KCTD3,EIF4G2,RGS17,PAN3,EIF1,EPB41,RCAN2,ERBB4,DLC1,FGF1,PCYOX1,PSD2,NBEA,MSANTD4,MPP6,FYN,GABRB3,GABRG1,GAD1,MALT1,RAB30,GLUL,KDM2B,GPR34,GPR37,GRM8,PSIP1,FAM222A,HMGCR,AGFG1,RBPJ,SCIN,JAK2,KCNQ3,MAP4,MARK1,MATN2,MBNL1,MEIS2,PPM1L,MITF,AFF1,MN1,MXI1,NCAM2,PCDH8,PDE1C,PFKFB3,KCTD15,FA2H,PPP2R2C,PPP2R5E,KANSL1,CEP41,PKIA,ANKHD1,ELOVL2,EML5,MARCH1,RAP1GDS1,GTDC1,RFX3,NUDT11,RORB,AP1AR,SALL1,SATB1,CSRNP3,SCAF8,CHD9,R3HDM2,BTBD7,EPC1,CXXC4,MYCBP2,IQSEC2,NFASC,LMO3,ANKRD12,FAM208A,CUX2,NSD1,CRTC1,GPRIN3,NACC2,CBX5,R3HDM1,KAT6B,NR2C2,DNALI1,PPP1R3F,ITM2C,FZD3,ADAMTSL3,MSRB3,JPH3" MicroRNA hsa-miR-33b:mirSVR_highEffct hsa-miR-33b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.71E-59 2.08E-55 1.83E-58 1.68E-57 152 865 "ABHD6,FMNL2,BEND6,SORCS2,CC2D2A,UNC79,CDC42BPA,DPP10,SEMA7A,PHF12,MAGEE2,TNRC6C,SPTBN4,ZNF583,SLC2A11,ADAM23,BACH1,ADGRB3,THSD7A,KALRN,PTBP2,USP6,CHN2,CLCN3,QKI,MAP4K4,IQCK,ARMC8,AKAP6,AKAP12,CS,RGS6,SEC24C,VCAN,SLITRK5,PHF14,ZFYVE16,MYEF2,PLPPR4,WDR20,RCAN1,ARRDC4,GOLT1B,E2F5,EBF1,EDNRB,FCF1,SEMA3D,EGFR,C8orf37,CALCRL,VPS13B,ANKMY1,EYA1,CLVS1,ABCA8,RPS6KC1,FER,OLFM1,FGF14,SMC2,ATP6V1H,CELF1,ERAP1,LRRC37A6P,SULT1C4,MSTN,GGTA1P,ZNF638,HTATSF1,GPD2,STON1,PRDM5,ZNF496,ADAMTS6,MAP4K5,RASSF8,HAS2,ZHX1,BACH2,HMGCR,HNMT,C9orf129,METTL21A,KCND2,LIG4,PAXBP1,LSS,MARK1,MATN3,MBNL1,MEIS2,MSR1,CNOT4,NPY,PDE4D,ENPP2,PLIN1,PCDH18,MTRF1L,PDZRN4,TRHDE,ING3,PPM1B,PPP3CA,MASP1,CNTLN,TMEM260,PTPN13,PTPRB,TTC13,ZNF615,MARCH1,RADX,ZDHHC14,RDX,RGS12,NUDT11,CARF,RPE,FBXW7,TRAPPC13,SCN8A,ARX,CPEB3,FAM81A,WDR47,SLC14A1,SNRPN,MYCBP2,IQSEC2,RBM26,VPS13A,AGTPBP1,KLHL4,SATB2,ZEB1,ZFPM2,ITGB3BP,CSMD1,KCNE5,UGT8,TBC1D15,XRCC4,ZNF711,TRIM9,LAMP5,EMSY,NAV3,WNK2,FAM13C,CPNE4" MicroRNA hsa-miR-365:mirSVR_highEffct hsa-miR-365:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.81E-59 2.13E-55 1.87E-58 1.72E-57 123 560 "CCDC85A,PTCHD1,SPOP,EP400,PHF12,UPRT,RGS20,ARRB2,PCDHGB4,DYNLL1,RNF182,DPY19L3,ADGRB2,SYNJ1,MTMR2,KALRN,CBR1,MTMR7,COPB2,CNTN1,MYRIP,ZFP28,CS,VCAN,PDE4DIP,ERC2,CCDC144A,DOCK4,HDAC9,PITPNC1,ZBTB24,TIAM2,GSDME,DDX46,RHOBTB1,GRIN3A,HS3ST2,NR1D2,DTNA,GOLT1B,EDN1,FSD1L,FAM13A,C3orf18,VPS13B,COQ7,NSRP1,STRADA,GORAB,FGF1,IP6K2,CELF1,CGREF1,MEGF10,GAA,DISC1,IGSF5,RAB30,TNRC6A,ZNF782,PRUNE2,FUT10,CCDC184,GRIK4,ADAMTS6,IRF8,KTN1,LAMP2,NCOA7,MARK1,MBNL1,ZNF680,COMMD5,ZNF92,NUCB2,CLDN11,P2RY1,PAX6,PCDHGC3,GNG2,TRHDE,ING3,GRAMD1C,SNRK,ZNF493,ZDHHC14,REV3L,PCMTD2,ABCA11P,ATXN2,SGK1,SEC31A,WDR37,SLC6A11,USP33,UHRF1BP1L,SSTR2,SYPL1,ANKRD28,TBCEL,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,CLHC1,SGK3,FAM155A,RICTOR,XPO1,ZNF708,SMARCAD1,PRDM10,FZD3,HNRNPA3,FAM198A" MicroRNA hsa-miR-552:mirSVR_highEffct hsa-miR-552:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.99E-59 2.79E-55 2.45E-58 2.25E-57 148 822 "KIAA1324,PCDH10,BBOX1,FAM135A,PHF12,PKP4,SEMA4G,RGS20,CADPS,LINC00173,TTLL9,CFLAR,DST,CAST,CBR1,CCNH,USP6,DGKI,LRBA,CLGN,LETMD1,TRIM69,CS,DCAF4,RHOBTB1,KIF19,EXOG,USP3,MAMLD1,FRY,MBNL2,EMX2,MFSD10,ANKMY1,ADGRV1,SCML2,FKTN,PPP1R1B,FER,MED12L,POLR1B,FGF12,SMC2,USP21,CELF1,CGREF1,NSG1,TVP23A,GABRA3,ZNF44,SULT1C4,ARFIP1,CYP46A1,RUNDC3A,FUT10,GRIN2C,GRM2,ZBTB49,SOX21,RASSF8,TNFAIP8L3,TCEAL6,IL6ST,NME9,ITGA7,LAMP2,ASPRV1,MATN3,MEIS1,NEK1,NELL2,NF1,NOVA1,DNHD1,NUCB2,ETFRF1,GPR173,PRIMPOL,DRAM2,TATDN3,PRKAR1B,MAPK10,KLK6,PTN,PTPRE,RASGRF1,KHDRBS2,RGS3,MRAP2,MCMBP,SEMA6D,SGK1,FERMT1,FNDC3A,ST6GAL1,NLGN1,BTBD7,ATF7IP,MBD5,MYO16,PDZD2,KDM3A,MYCBP2,MPRIP,ADHFE1,SUPT5H,SYPL1,COBL,MTCL1,DNMBP,SIN3B,ZEB1,RPGRIP1L,SYNE1,DOCK9,PCDHAC2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,TIAM1,R3HDM1,C9orf85,ELP5,AMACR,TRO,PPIL6,RUSC1,ZKSCAN5,UGT8,VLDLR,XPO1,ZBTB14,ZNF74,ZNF225,STOX2,PPP1R3F,FIP1L1,PCBP4,WNK2,KLHDC1,IFT88,RNF146" MicroRNA hsa-miR-338-3p:mirSVR_highEffct hsa-miR-338-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.73E-59 3.21E-55 2.81E-58 2.59E-57 149 834 "ACADM,TMCC3,PWWP2A,KIAA1211,ESYT2,ZNF608,MTUS1,MAP4K3,MARCH3,MARK4,ZBTB10,ZNF582,BLM,CFLAR,BMP7,SYNJ1,JAZF1,C5,THSD7A,CAPN3,DGKI,LRRFIP1,MAGI1,CDR1,CLCN3,LY86,LETMD1,SLC4A8,SEC31B,AKAP12,ANKRD44,UBXN2A,HDAC9,DGKB,JAKMIP2,MYEF2,WDR20,KIF19,DTNA,DNAJB6,PHF20L1,COPS4,PLEKHA1,F8,ZNF589,ATP13A4,FLT1,UFM1,PRELID3A,SDCBP2,CHL1,GALNT15,ZNF559,TUBGCP4,TOX3,DCLK2,GPD2,LILRA2,GRIA2,ZBTB49,FRMD3,NCKAP1L,HNF4G,ZNF678,FAM69A,SLC35G1,KCND2,CREG2,STXBP5,SYTL4,NCOA7,MBD1,MBNL1,TM6SF1,SRSF12,BLOC1S2,ZNF862,NDP,IDNK,CNOT4,NOVA1,SCHIP1,SEPT4,PPM1B,TATDN3,APTX,GDPD2,PTCH1,PTN,PTPRG,ACSM5,QDPR,RAD51D,ZNF493,RDX,ZFHX4,CARF,ELP2,EPHA10,FBXW7,ATP8B4,RTN1,ATXN7,FNIP1,ZFP2,SH3GL3,CPEB3,PREX2,SLC12A4,ARFGAP1,MYH15,LIMCH1,MBD5,SP4,LMO3,CLASP2,TROVE2,LARP4,NEK4,SEPT8,ADHFE1,PRRC2C,VPS13A,SYN2,COBL,MTCL1,TAF9,PCDHGA11,GPRIN3,C18orf54,SLC44A1,ERCC6L2,CSMD1,TPM1,RUNDC3B,AMACR,WIPF1,ZNF70,FTSJ1,EMSY,CADM2,HPS4,NELFE,RGS7BP,FZD3,CASC15,NHSL1,ZNF30,CPNE4" MicroRNA hsa-miR-659:mirSVR_highEffct hsa-miR-659:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.56E-59 4.23E-55 3.70E-58 3.41E-57 166 1033 "KCNH8,KLHL32,PWWP2A,RNF150,CC2D2A,HFM1,SMIM17,ALCAM,ABCD2,UNC79,NCOA1,ZNF583,DOCK11,TTLL9,RGS9,BID,DST,SYNJ2,SCAPER,KALRN,SPAG9,CD86,CBFA2T2,SEPT7,TIGD7,RAB33A,CNN3,IQCK,CABP1,AKAP5,SLC35F1,FAM171B,ENTPD4,NCOR2,ARHGEF10,SLITRK5,HDAC9,DCAF8,JAKMIP2,FAM107B,DMTF1,DTNA,DNM1L,FCF1,SEMA3D,FRY,TUBD1,NCALD,SPEG,TLR7,SIRPB1,F5,CLVS1,SCML2,CEP78,FCGR3A,GORAB,SLC9B2,FGF12,FGF14,NELFCD,NBEA,POMT1,ZBED3,ATP2C1,STAU2,GAD1,FAM120B,DISC1,KIAA1841,PPARGC1A,LYVE1,TNRC6A,FUT10,FAM19A2,VSIG4,NEGR1,CELF5,SMAP1,JAK2,KCNN3,KHK,LAMP2,MAP4,KCTD6,BLOC1S2,THYN1,MYO6,NOVA1,GPR137C,CNTN3,PCSK1,PIK3C2A,SNX10,MTRF1L,PRIMPOL,MINDY2,PRKACB,PRKCB,MAPK9,PRPH,RELN,SNRK,MTMR10,SPDL1,TMEM260,PTX3,ZSCAN2,TUG1,PPP2R3C,ACSS3,REV3L,ZFHX4,ROBO1,NEK11,RPL15,CCDC112,SEMA6D,LRFN5,FNIP1,TNFRSF19,SH3GL3,NLGN1,PPP4R3A,FAM214B,BTBD7,ZNF667,TTC17,IFT122,LIMCH1,TMCC1,TRERF1,ZC3H13,CDK19,SPART,NFASC,CEP68,NSFL1C,SYP,SYPL1,C12orf76,DNMBP,FAM208A,ADGRL3,IQCE,TCF12,DOCK9,CYB561A3,ACTR6,RGMB,BCL2L13,CLDND1,RICTOR,ZIC2,KCNT2,POLR3H,SLC30A4,RNF103,HPS4,MDH1B,NAV3,PDSS2,SMIM8,PHTF2,FRMD6,DPF3" MicroRNA hsa-miR-193b*:mirSVR_highEffct hsa-miR-193b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.30E-59 5.20E-55 4.55E-58 4.19E-57 149 837 "ABHD6,FZD9,RNF150,BEND6,CC2D2A,FAM135A,MYH7B,UPRT,INSYN2B,SGCE,CACNA1B,CAMK2G,LDB2,CERS5,DGKI,SRSF11,CHN1,CPNE6,NRXN3,PLAA,MYL6B,MAP4K4,CNGA3,COL9A1,GAL3ST1,SMARCAL1,ZFP28,SLC35F1,SEC31B,CLOCK,C1QL2,GDA,CS,CSF1,CSF2RA,APPL1,UBXN2A,CTH,DCAF4,RUBCN,ARHGAP32,AIF1L,ARMCX4,SNAP91,SV2B,DLX1,DMD,DMPK,DNM1L,GOLT1B,EDNRA,PHF20L1,SUGP2,EIF1,EMX2,RABEPK,IGSF6,ETV1,F5,SLC9B2,FGF1,FGFR1,FHL1,MEX3B,TMEM107,ERGIC3,ST6GALNAC3,STAU2,B4GALNT1,ARFIP1,PCDH17,CRCP,GLYR1,TNRC6A,MSL3,GLUL,GPD1,PCLO,GRIK5,IRAK3,ELOVL5,HMGCL,ZNF491,ZDHHC15,SMAP1,EID2B,RBPJ,IL6R,LRRTM1,SMAD9,MAP6,MMP16,IDNK,VWA2,NTRK3,PCSK1,TMEM38A,PMP22,SH3KBP1,NKAIN4,MAPK3,GDPD1,SNRK,PTPRD,ZNF793,ZMAT4,RNASEL,CARF,YY1AP1,ATAT1,CLIP1,TRAPPC13,FAM192A,TNFRSF19,SHC4,FHOD3,FAM81A,DHX30,SEPHS1,CCDC88A,SLC14A1,PDZD2,PEG10,ZC3H13,TSPYL2,SEPT8,SULF2,SEPT3,NECAB1,SYN1,SYNE1,PCDHB9,SLC19A3,TNS2,CCDC173,ZMAT3,ARL10,TIAM1,TIMP4,CSMD1,IL34,PLEKHH2,BCL2L13,RICTOR,ZIC1,NDRG4,ZNF138,SIGLEC10,RNF170" MicroRNA hsa-miR-2115:mirSVR_highEffct hsa-miR-2115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.34E-59 5.23E-55 4.57E-58 4.21E-57 161 975 "ACADM,NDRG3,FZD9,CC2D2A,PKP4,APC,UPRT,DDO,ARNTL,LINC00173,ATP2A2,ATP2B2,ATP6V0A1,ADAM23,TTLL9,CALB1,CALB2,KALRN,CARS,ZNF501,CCNH,DLGAP2,CLTB,NGEF,RCHY1,BAG4,SNCAIP,CSNK1G3,CST3,GREB1,RUBCN,CENPL,GIT2,ARMCX4,ARMCX2,YTHDC1,RHOBTB1,ZNF582-AS1,HS3ST2,DMTF1,DRP2,ABCC5,DNM1L,EBF1,PHF20L1,TMEM132E,ASB3,COPS4,PCOLCE2,CALCRL,CDKL3,DNAJC27,FKTN,FDFT1,OLFM1,AMOTL2,FHL1,POLK,SUCO,JKAMP,UFM1,PDLIM5,STAMBP,ERAP1,DISC1,LRRC37A6P,SULT1C4,SESN1,COPS8,ZNF638,WDFY3-AS2,GPD2,LPAR4,GPR37,PCLO,PLCD4,MIER3,LRRCC1,DISP2,FAM69A,KCNN2,KIFC3,STXBP5,LAMP2,PAXBP1,HECTD2,MARK3,MXI1,LYRM9,NACA,NFE2L2,OCRL,PCDH8,ENPP2,PFKFB2,PIK3C2A,GPSM2,JAKMIP1,PCDH18,PSAT1,PPARA,PPM1B,RASGEF1B,PKIA,MAPK9,APTX,PTK2,PEX2,RDX,TMLHE,CARF,RORB,ELP2,CCDC102B,KCNIP1,RYR3,ATXN2,SMPD3,SGK1,SH3BGR,ST6GAL1,PPP4R3A,ARHGEF40,SLC9A5,BTBD7,EPC1,RCOR3,ANKRD36,IQSEC2,ZC4H2,NKAIN2,SS18,ERBIN,DIP2A,ADHFE1,VPS13A,ADAMTS17,CAMTA1,SATB2,USP22,PCDHB4,ZFPM2,SLC44A1,MTMR14,TMPO,NPL,CHST5,RGMB,TRO,RPL7L1,CCDC136,WIPF1,GUSBP1,XRCC4,MICU3,UPF3A,CADM2,NAV3,NELFE,FAM13C,ADAMTSL3" MicroRNA hsa-miR-1323:PITA hsa-miR-1323:PITA_TOP PITA 1.01E-58 5.63E-55 4.91E-58 4.52E-57 133 665 "AP2A1,INTS2,OSBPL1A,OSBPL8,SEMA6A,ALCAM,AMPH,CDC42BPA,DPP10,MAP4K3,TMEFF1,ZBTB10,CHRD,SLC4A4,NRP2,SYNJ1,RUNX1T1,C1orf52,FOXN3,B4GALT6,LHX2,NRXN3,CLTC,TMEM184B,MAGED1,CLOCK,CRMP1,GDA,CSNK1G3,SLITRK5,ERC2,RIMS2,KIAA0408,DOCK4,ZC3H11A,FAM107B,USP3,CPEB2,CASP8AP2,DNAJB6,HIPK3,SEMA3D,KMT5B,GOLGA7,EIF4G2,PLEKHA1,PAN3,ETV1,FGFR3,GABRB3,PCDH17,PPARGC1A,GRB10,CIT,SOX21,ZHX1,BACH2,MIER3,HLF,HMGCR,KIT,KTN1,MBNL1,LRP1B,MEF2C,MYCN,MYO6,NEXMIF,MYT1,NOVA1,PCSK1,GPR85,GNG2,RETREG1,NLE1,STRN3,PPARA,PPP2R5E,VSTM2L,PTPRD,PTPRG,USP47,OXR1,FIGN,RFX2,SLC25A36,ZFHX4,PCMTD2,RPE,CLIP1,RTN1,FNIP1,TNFRSF19,HSPA4L,KIF21A,FBXO11,PPP4R3A,EPN2,NAPB,ATF7IP,FAIM2,PDZD2,SOX15,SP4,KDM4C,CLASP2,SS18,ST5,KLHL7,PLCB1,CAMTA1,TBL1X,TCEA1,RPGRIP1L,SYNE1,TEK,TMEM121,TIAM1,ERCC6L2,TUBB2A,SGK3,RPRM,UBTF,UGT8,FLRT2,VGF,WIPF1,ZFAND5,EMSY,MFF,PRDM8,NAV3,SOCS4" MicroRNA hsa-miR-548o:PITA hsa-miR-548o:PITA_TOP PITA 1.01E-58 5.63E-55 4.91E-58 4.52E-57 133 665 "AP2A1,INTS2,OSBPL1A,OSBPL8,SEMA6A,ALCAM,AMPH,CDC42BPA,DPP10,MAP4K3,TMEFF1,ZBTB10,CHRD,SLC4A4,NRP2,SYNJ1,RUNX1T1,C1orf52,FOXN3,B4GALT6,LHX2,NRXN3,CLTC,TMEM184B,MAGED1,CLOCK,CRMP1,GDA,CSNK1G3,SLITRK5,ERC2,RIMS2,KIAA0408,DOCK4,ZC3H11A,FAM107B,USP3,CPEB2,CASP8AP2,DNAJB6,HIPK3,SEMA3D,KMT5B,GOLGA7,EIF4G2,PLEKHA1,PAN3,ETV1,FGFR3,GABRB3,PCDH17,PPARGC1A,GRB10,CIT,SOX21,ZHX1,BACH2,MIER3,HLF,HMGCR,KIT,KTN1,MBNL1,LRP1B,MEF2C,MYCN,MYO6,NEXMIF,MYT1,NOVA1,PCSK1,GPR85,GNG2,RETREG1,NLE1,STRN3,PPARA,PPP2R5E,VSTM2L,PTPRD,PTPRG,USP47,OXR1,FIGN,RFX2,SLC25A36,ZFHX4,PCMTD2,RPE,CLIP1,RTN1,FNIP1,TNFRSF19,HSPA4L,KIF21A,FBXO11,PPP4R3A,EPN2,NAPB,ATF7IP,FAIM2,PDZD2,SOX15,SP4,KDM4C,CLASP2,SS18,ST5,KLHL7,PLCB1,CAMTA1,TBL1X,TCEA1,RPGRIP1L,SYNE1,TEK,TMEM121,TIAM1,ERCC6L2,TUBB2A,SGK3,RPRM,UBTF,UGT8,FLRT2,VGF,WIPF1,ZFAND5,EMSY,MFF,PRDM8,NAV3,SOCS4" MicroRNA hsa-miR-154:mirSVR_highEffct hsa-miR-154:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.38E-58 7.72E-55 6.73E-58 6.19E-57 151 862 "KLHL32,ADD1,BRAP,MTUS1,OGT,LGR5,CDK13,CCDC74A,TMEM108,ADGRB3,BBS2,KSR1,BMPR1B,SYNJ2,ARHGEF7,RAB29,CALB1,PTBP2,CAMK2G,CBS,MTMR7,LRRFIP1,CFL2,SRSF11,FOXN3,NRXN3,PLAA,MAP4K4,ARMC8,CLOCK,CS,SUSD5,SOCS5,CST3,UBXN2A,CTH,ZSCAN23,LIN54,DGKB,CPEB2,DMTF1,ACOT8,RCAN1,DTNA,ECM2,GOLT1B,E2F5,KLHL5,FRY,FAM13A,GOLGA7,COPS4,RCAN2,CEP78,KAT8,GORAB,SEC24B,FGF14,FHL1,CHL1,GABRG2,IQGAP2,DISC1,GATM,LYVE1,HPGDS,ZNF638,ADGRA3,LPAR4,ATP2B1-AS1,KAT7,PSIP1,MIER3,ELOVL5,TCEAL6,SOWAHA,SCIN,HECTD2,MAP4,MKLN1,AFDN,XRRA1,NRBP2,CNOT4,PCBP3,FAM218A,MINDY2,PPP2R5E,GRAMD1C,GDPD1,MASP1,WBP1L,TMEM260,TMEM255A,RET,GTDC1,ZNF532,GLDN,STK32B,MAP6D1,TRAPPC13,SALL1,FNIP1,SUPT20H,HSPA4L,ZFP30,ASAP3,CPEB3,ANKRD6,PPP4R3A,PKNOX2,CPEB4,SMARCD3,SNRPN,SOX3,SP4,SPP1,RBM26,LARP4,NXT2,NEK4,ARHGEF9,PLCB1,TBCEL,SATB2,CUX2,TCF12,PCDHB4,TIAM1,HEY1,ELP5,AMACR,ZNF709,TBC1D15,CLDND1,CFAP298,ZFP37,KCNT2,AGMO,TMEM237,ZSCAN26,MFF,CADM2,HPS4,DNAH10,FZD3,FBXO36,TTC7A,FXR1,NETO1,GAN" MicroRNA hsa-miR-200a*:mirSVR_highEffct hsa-miR-200a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-58 8.09E-55 7.05E-58 6.49E-57 150 851 "XKR4,BRAP,KLHL13,KCTD16,NME5,ADGRF5,OGT,MAP4K3,SLC2A11,BMPR1B,DST,ST3GAL5,SYNJ2,KALRN,RUNX1T1,CCK,CNOT8,TPP1,QKI,CNR1,ABI3BP,RCHY1,FAM171B,PREPL,HAPLN1,SEC24C,IPCEF1,SLITRK5,PITPNM3,PHF14,CTH,TCAF1,ZFYVE16,BRINP1,ARMCX4,PITPNC1,TIAM2,GSDME,DDX46,DPP6,E2F6,EDNRA,FRY,GPHN,STX2,CEP85L,DNAJC27,F5,CLVS1,DLC1,MED12L,FGF13,MEX3B,ATP6V1H,ERGIC3,ST6GALNAC3,CHL1,DISC1,IGSF5,SULT1C4,MSTN,ARFIP1,COPS8,GLUL,KDM2B,PRUNE2,ATP2B1-AS1,ZHX1,MIER3,SHISA6,EID2B,RBPJ,KCND2,KCNJ16,CREG2,STMN1,HECTD2,PIK3AP1,MAP4,MARK1,MBD1,MBNL1,MEIS2,ZNF680,MSR1,ZNF92,NCF2,NEK1,NOVA1,SMIM11A,ETFRF1,PDE3A,GPR85,GNG2,PIK3C2A,ING3,TMEM260,ZSCAN32,PEX2,RAD51D,ZNF493,MORC4,SLC25A36,NUDT11,CARF,GSTCD,PCMTD2,CCDC102B,RPE,ABCA11P,ST6GALNAC6,CSRNP3,SCN2B,SGK1,SH3GL3,ZNF430,SLC14A1,BTBD7,SLC22A4,LIMCH1,SNRPN,GLT8D1,KDM4C,SSTR2,ZSCAN29,NEK4,ARC,TCEA1,USP22,PCDHB6,DICER1,ZFPM2,BHLHB9,TMPO,TUBB2A,EIF4ENIF1,UBE3A,MTCH1,WRN,CLDND1,ZNF708,KCNT2,ZNF138,ANKS1B,PRDM10,FZD3,HNRNPA3,PHTF2,FRMD6,GAN" MicroRNA hsa-miR-512-3p:mirSVR_highEffct hsa-miR-512-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-58 9.15E-55 7.96E-58 7.33E-57 144 785 "KCNH8,KLHL32,KIAA1211,PTCHD1,FAHD2CP,AK2,SPOP,PCDH10,APC,UPRT,TNRC6C,LGR5,DST,SYNJ2,PTBP2,MTMR7,LRBA,RCBTB2,B4GALT6,ABCG2,QKI,ARMC8,SUMF2,LETMD1,SLC4A8,ENTPD4,CRHBP,ABCG1,ARHGEF10,CTH,GREB1,BOC,HDAC9,ZFYVE16,DBI,ZNF804A,HS3ST2,USP3,FAM78B,DNM1L,EDNRA,EDNRB,HIPK3,PHF20L1,MBNL2,FER,FGF13,POLK,SUCO,C2orf88,OGA,ERAP1,DISC1,MSTN,PPARGC1A,GLUL,DCLK2,LOXL3,PSIP1,MSL1,SLC35G1,KHK,STXBP5,NCOA7,SMAD9,MAN2A2,MAT2A,MBNL1,MXI1,NEK1,NFE2L2,PDCD2,PRTG,NALCN,PKD1,TRHDE,LRP12,PPP2R5E,PPP3CA,PKIA,MAPK10,GRAMD1C,HYDIN,TMEM260,PTPRG,PTPRO,PEX2,FAT4,RAP1GDS1,ENOX1,RFX3,CARF,ROBO1,RORB,RPS20,SALL1,SEMA6D,ATXN7,TNFRSF19,SHC4,CHD9,ATF7IP,ZFP1,IFT122,FAM219A,SP2,CLASP2,TROVE2,SS18,ADHFE1,C12orf76,CAMTA1,ATMIN,ZEB1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ITGB3BP,AKTIP,NR2E1,PIK3R5,TPM1,NPL,TRO,UGT8,GUSBP1,ZNF711,ZSCAN26,ANKS1B,ZNF213,CADM2,NELFE,EPM2A,MARCH8,UBE3B,KAT6A,JMJD1C,ZNF30" MicroRNA hsa-miR-1269:mirSVR_lowEffct hsa-miR-1269:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-58 1.03E-54 8.94E-58 8.23E-57 186 1289 "ASIC1,EMILIN3,SYS1,ADD2,KIAA1324,SPARCL1,SPOP,FAM135A,MYH7B,SHROOM2,RGS20,MARK4,EIF4G3,STX16,DPY19L3,RGS11,CASTOR3,GPC2,CA8,KALRN,VXN,CAST,DCLK1,UBE2L6,NPIPA1,SOCS6,PPT2,CLCN3,FAM19A5,CNGA3,FHL5,AKAP6,LETMD1,SMARCAL1,ZFP28,NECTIN3,ZNF385A,CLOCK,PREPL,GDA,ABCG1,ARHGEF10,PHF14,RUBCN,CCDC144A,ARHGAP32,TMEM130,KIF19,GRIN3A,NR1D2,DMTF1,DPP6,ACOT8,DTNA,AASDH,EDNRA,RASGRP1,KLHL5,PHF20L1,PLEKHA1,TMEM35A,MRPL37,CDKL3,SIRPB1,FAM198B,ZNF461,PTK2B,STRADA,SEC24B,FLT1,COQ5,TMEM175,KHDRBS3,MPP6,ZMAT1,MEGF11,GABRG1,FAM120B,GALC,RAPGEF6,GPR162,STON1,ZNF496,PADI2,HNMT,LRRC75A,ZNF546,IGF1,KNDC1,TJAP1,SLC6A17,KCND1,LAMP2,SYTL4,NCOA7,MAP4,MARK1,MAT2A,AFF1,N6AMT1,MYO6,P2RY13,NRCAM,NTRK2,PDE4B,NALCN,KCTD15,PLTP,MTRF1L,ANKRD16,PMP22,SCHIP1,PPM1B,PPP2R2B,PRKACB,CEP41,GRAMD1C,HYDIN,PRPSAP2,VPS13C,MTMR10,C1orf109,IQSEC3,NWD1,DPF2,RFX2,CARF,PCMTD2,SNX22,TCP11L1,FAM161B,HUNK,KCNIP3,ZNF331,TNFRSF19,TRA2B,CHD9,FNDC3A,NLGN1,ANKRD6,SLA,ARHGEF40,CXXC4,CDK5RAP2,RCOR3,FAIM2,PDZRN3,MYO16,DOP1A,PDZD2,UHRF1BP1L,KDM4C,ZNF423,NFASC,COBL,ANKRD28,MMS19,ADGRL3,FRYL,TEK,BHLHB9,BEX4,RIMBP2,PRRT1,KAT6B,TPM2,TRPM2,PPIL6,DCBLD1,ZKSCAN5,CLHC1,TBC1D15,WIPF1,KLC2,KCNT2,TRIM9,CRB2,ZNF154,FSTL5,PRDM10,SLC17A7,FBXO36,FAM219B,TIGD6,FXR1,SENP7" MicroRNA hsa-miR-3065-3p:mirSVR_highEffct hsa-miR-3065-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.07E-58 1.16E-54 1.01E-57 9.28E-57 149 842 "KCNH8,ACADM,CLK4,KLHL32,PLEKHH1,RNF150,OLMALINC,MTUS1,ZNF578,SMIM17,SPOP,FAM135A,BIN1,ATP2A2,PROM1,MTMR2,DDR1,KALRN,PTBP2,CAMK2G,SLC25A14,ARHGEF25,SRSF11,FBXO7,ARMC8,SLC4A8,SLC35F1,CPS1,CLOCK,CRMP1,HAPLN1,CTH,GAPVD1,DGKB,BRINP1,ARMCX2,DDX46,PLPPR4,SACS,DTNA,PHF20L1,KCTD3,PLEKHA1,EPB41L2,RCAN2,MTSS1L,SH3YL1,MED12L,FGF13,NBEA,POMT1,SMC2,SPECC1,TRIM16,NSG1,MSANTD4,OGA,DISC1,ACSS1,SESN1,PCDH17,DBF4,TNRC6A,MSL3,POLL,GP1BB,STMN2,ADAMTS13,RASSF8,ZHX1,ELOVL5,HMGCL,HMGCR,HNF4G,ZIC5,ZNF678,GPR62,KCNN2,MAT2A,MEST,ZNF862,ETFRF1,ENPP2,ZNF655,JAKMIP1,EXOSC10,EPB41L4B,POLR2F,PRKACB,MASP1,VPS13C,CNTLN,CASTOR1,C1orf109,CCDC40,RAD51D,RET,ERI2,GTDC1,RNASEL,ELP2,RPL15,ADAL,SEMA6D,SMPD3,SH3GL3,CPEB3,MYO18A,NLGN1,NUBPL,SLC8A1,SLC12A4,TET1,CPEB4,MYH15,SNCA,BDP1,ZSWIM8,ZSCAN29,CEP68,PRRC2C,ADAMTS17,TBCEL,HIF3A,FAM200B,SIRT1,ITGB3BP,AP4E1,ARL10,TMEM9,TPM1,NEIL2,TRPS1,RUSC1,CLEC2L,UGT8,PLEKHH2,ZNF45,SLC30A3,MAP3K12,EMSY,CADM2,TUBA1A,NAV3,URM1,TRIM16L,FZD3,PRRT4,FAM198A" MicroRNA hsa-miR-205:mirSVR_highEffct hsa-miR-205:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.42E-58 1.36E-54 1.18E-57 1.08E-56 159 958 "RNF150,PTCHD1,AP2A2,INTS2,MTUS1,HACE1,AK2,ALCAM,CEP126,ABCD2,UPRT,PPP4R4,ATP2A2,CFLAR,CALB2,KALRN,AP4M1,MAGI1,CFL2,CHN1,MS4A7,B4GALT6,CLTC,NGEF,QKI,NCOR1,GDA,RGS6,CSF2RA,PDE4DIP,ERC2,PHF14,PNPLA8,CYBB,HDAC9,ZFYVE16,TMEM170A,GUCD1,SV2B,ZNF582-AS1,CDON,CPEB2,DNM1L,EDN3,PHC2,ANKRD46,CNNM1,RASGRP1,CALCRL,EPB41,RCAN2,EPHB1,CEP85L,CLVS1,ACSL4,ST3GAL6,ZSCAN30,SEC24B,FGF12,RGPD5,NOP56,COQ5,EFCAB2,SMC2,ST6GALNAC3,SARAF,TRAF3IP2,DISC1,LRRC37A6P,IGSF5,SULT1C4,GGT7,ZNF638,CBX1,KDM2B,STMN2,GRIA2,FAM19A2,SHISA6,ZNF678,KCNJ16,IPO5,NCOA7,MARK1,MBNL1,NCAM2,NEK1,SMIM11A,TBC1D25,CLDN11,PCSK5,PDE1C,OLA1,ZNF655,FAM218A,PURG,SEPT4,EPB41L4B,DRAM2,PPP2R5E,PRKACB,GRAMD1C,TMEM260,ZIK1,C1orf109,ZNF615,ZNF844,SLC25A48,RBBP8,ZMAT4,RGS12,RIC8B,ZFHX4,MCMBP,LRRK2,ABCA11P,CLIP1,SCN8A,SEC14L1,SH3GL3,SLC2A5,BTBD3,SEPHS1,NAPB,TET1,CXXC4,SP4,UHRF1BP1L,KDM4C,CDK19,RBM26,ZNF302,SS18,PLCB1,COBL,TAF9,DMXL2,SATB2,CUX2,ZEB1,TNS2,AP4E1,NACC2,ERCC6L2,TP53BP2,TTC3,FAM155A,PCDH20,MICU3,KCNT2,TRIM9,FSTL5,ZNF184,PCBP1-AS1,ZFAND5,ADAMTS9,PDSS2,HRASLS,SPATA13" MicroRNA hsa-miR-649:mirSVR_highEffct hsa-miR-649:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.51E-58 1.40E-54 1.22E-57 1.12E-56 160 970 "SYN3,BRAP,KIAA1211,ALCAM,AMPH,CDC42BPA,DDO,USP37,CDK10,NUMB,TMEM108,BBS2,PROM1,MTMR2,JAZF1,IL33,KALRN,LY86,SLC4A8,TOGARAM2,GDA,CSNK1G3,ERC2,PHF14,RIMS2,RUBCN,HDAC9,GAPVD1,ZFYVE16,EARS2,DAPK1,PABPC5,SNAP91,CHRDL1,DMD,DMTF1,DPP6,PDCD6IP,DNM1L,GOLT1B,EBF1,YAF2,FAM13A,KMT5B,EGR3,EIF4G2,C8orf37,DCTN4,EIF1,EMX2,VPS13B,MFSD10,NCALD,CDKL3,SCML2,GORAB,PCYOX1,JKAMP,ATP2C1,ABLIM2,TVP23A,INPP5K,NEU3,SESN1,KIAA1958,GPD2,PCLO,CNTRL,STMN2,FRMD3,BACH2,HLF,IRF8,MYLK2,ZIC5,INPP5B,KIF5A,LIMS1,MARK1,MARK3,MBD1,MBNL1,KITLG,MID1,NFE2L2,SLC11A2,NRCAM,OCRL,OGG1,OPA1,GPR137C,PDE4D,SLC10A4,MAPKAP1,PRKAB2,VPS13C,ZNF615,OXR1,RASGRF1,GTDC1,CCDC102B,RPS6KA2,NCBP3,TRAPPC13,SH3BGR,CHD9,R3HDM2,WDR37,FAM81A,PPP4R3A,KDM4D,CCDC88A,TET1,LIMCH1,FAM126B,LMO3,POGZ,SS18,KANK1,SYT1,ANKRD12,FAM208A,ADGRL3,TBCEL,ZEB1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,AP4E1,ERCC6L2,R3HDM1,C9orf85,UBE2H,SLC35A4,FLRT2,BCL2L13,CCDC14,CLDND1,PCDH20,ZNF711,ZNF19,KCNT2,AGMO,REEP1,ZSCAN26,ANKS1B,EVI5,FAM47E,PDSS2,AMN1,PHTF2,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-891b:mirSVR_highEffct hsa-miR-891b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-58 1.73E-54 1.50E-57 1.38E-56 155 913 "ACADM,FMNL2,PWWP2A,SLC24A4,OSBPL1A,WDR35,HFM1,FAM135A,ANK2,CCDC146,MAP4K3,APOC2,BCAS1,NUMB,DPY19L3,SEC11C,SYNJ1,MTMR2,IL33,VXN,ISPD,CLDN10,LDB2,KRIT1,TIGD7,DIS3L,SRSF11,NRXN3,ABCG2,AKAP6,CPS1,CREM,TRIM69,OSBPL3,PDE4DIP,PHF14,ARHGEF4,CCDC144A,DOCK4,HDAC9,ARHGAP32,LONRF1,PITPNC1,GSDME,DYNC1I1,ARRDC4,EDN1,SEMA3D,TMEM35A,CD320,GORAB,SUCO,IP6K2,FOXO3,FOLH1,SMC2,UFM1,PDLIM5,ATP6V1H,AP4B1,GABRA3,GAD1,GCNT2,COPS8,TNRC6A,CBX1,PCLO,FAM19A2,RASSF8,ZHX1,FRMD5,MIER3,HNMT,SMAP1,FAM69A,KCNJ16,TTYH2,LIG4,LYPLAL1,ADAM22,NEK1,NF1,ENPP2,GPR85,PIK3R1,SMIM7,PSAT1,DRAM2,PPP2R5E,GRAMD1C,PRPSAP2,APTX,SNRK,QRICH1,ANKHD1,TMEM260,PTPRD,QDPR,FAT4,RAP1GDS1,GTDC1,FIGN,FBXW7,SPIN3,ZC3H14,ABCA11P,CCDC112,SUPT20H,PPM1E,CHD9,NLGN1,CCDC88A,FNBP1,KDM3A,NMNAT2,KDM4C,SS18,ELOVL4,SEPT8,SYNE2,VPS13A,SYPL1,COBL,TCF4,PCDHGA4,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,AKTIP,ERCC6L2,KAT6B,TPM1,SSBP2,TUBB1,FAM155A,FLRT2,PLEKHH2,VLDLR,P2RY12,WRN,XPO1,ZFAND5,HPS4,TRIM16L,WNK3,PLSCR4,AMN1,FXR1,FRMD6" MicroRNA hsa-miR-4279:mirSVR_highEffct hsa-miR-4279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.25E-58 1.82E-54 1.57E-57 1.45E-56 159 960 "PWWP2A,CC2D2A,ARHGAP20,UPRT,DDO,SEMA4G,PPP4R4,CASK,NCOA1,SLC2A11,ATP6V1G2,RGS9,CACNB4,ARHGEF25,ZNF501,CCNH,CCNT1,P2RX6,ZMYM4,LARGE1,CLCN3,SRP14-AS1,IGLON5,IGDCC3,HAPLN1,CSF2RA,ARHGEF10,PLCXD3,PNPLA8,RUBCN,CCDC144A,GAPVD1,ZFYVE16,DGKB,DGKG,DAPK1,DBI,ARMCX4,SV2B,DMD,DNM1,DPYSL2,E2F5,AASDH,MBNL2,RCAN2,NCALD,CDKL3,ETV1,EXTL2,EZH1,F8,CLVS1,MED12L,FGF1,PRKAG2,MEX3B,SLC37A3,NOP56,NELFCD,SPECC1,MEGF11,C15orf41,DISC1,IGSF5,GPR162,PCDH17,ZNF276,GLI2,GPER1,STMN2,GRIA2,PLCD4,SERP2,COQ10A,HLF,SYNPO,MSL1,ITGA7,KCND1,KCNN3,STXBP5,TTYH2,LIMS1,ZFYVE27,MBNL1,LRP1B,AFF1,AFDN,MMP16,MSR1,MYO7A,ZNF862,NF1,CNOT4,DNHD1,P2RX7,GLIPR1L2,GNG2,SH3KBP1,C19orf57,PPM1B,PPP2R2B,GRAMD1C,WBP1L,LAMA1,PIGG,MTMR10,PTK2,TMEM260,ZSCAN2,RAD51D,ENOX1,OXR1,GSTCD,ROBO2,SPIN3,TCP11L1,ATXN7,SCN8A,SMPD3,FNDC3A,ANKRD6,FAM81A,SLC6A11,BTBD7,CPEB4,RCOR3,IFT122,DBNDD2,ZBTB43,CLASP2,ADAMTS17,SYN2,ASTN2,TCEA1,ZFP90,SZT2,SYNE1,DOCK9,SLC19A3,KHDC1,SLC44A1,FAM124A,WBP2,ZNF346,AMACR,UBE3A,USP1,ZIC1,ZNF74,LYPD6,ZSCAN26,UPF3A,DNALI1,RNF103,DOCK8,KAT6A,LAS1L" MicroRNA hsa-miR-3128:mirSVR_highEffct hsa-miR-3128:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.95E-58 2.21E-54 1.91E-57 1.76E-56 167 1057 "NCKAP5,KLHL13,HACE1,ALCAM,DPP10,VAT1L,ZFYVE28,ZBTB10,ATP1B3,DPY19L3,DST,RAB29,CAST,KYAT1,USP6,RGN,ARHGEF1,PLAA,SRP14-AS1,COL4A5,TOGARAM2,CNRIP1,SLC35F1,PREPL,ARHGEF10,SIPA1L1,DZIP3,GPRASP1,IST1,ARMCX4,ZC3H11A,WDR20,NYAP1,DMTF1,ARRDC4,DNAJB6,DNM1L,SNX29,EDN3,EDNRB,HIPK3,FCF1,MBNL2,KCTD3,PLEKHA1,TMEM35A,SRRM1,ETV1,GORAB,SLC9B2,MED12L,MEX3B,FOXF2,ATP13A4,FLT1,PDLIM5,STAMBP,STAU2,SIGLEC8,ALDH1L1,GGT7,TCERG1,GRIA2,RNF165,MAP4K5,RASSF8,UBE2QL1,NXPH3,FRMD5,VSIG4,TCEAL6,HSPA1L,MSL1,ZIC5,RBPJ,ZNF678,ITPKB,KTN1,TTYH2,MARK1,LYPLAL1,MAT2A,MEIS2,MEST,TAGLN3,TCEAL5,PCDH9,PDE4D,PFKFB2,PFKFB3,PLCL1,EPB41L4B,PPP2R2B,RASGEF1B,CEP41,MAPK10,GRAMD1C,TMEM260,PTPRB,PTPRD,PTPRG,ZSCAN2,TTC13,CEP97,FAT4,OXR1,RASGRF2,RADX,KHDRBS2,RFX3,SETD5,CARF,CCDC25,ELP2,PCMTD2,ATP8B4,ATAT1,SCP2,NLGN1,SEC31A,SLC2A5,SLC6A11,CCDC88A,SLC12A2,NAPB,ATF7IP,LIMCH1,CMTR2,DOP1A,ZNF423,CLASP2,ITPRID2,ELOVL4,SEPT3,NSFL1C,ARHGEF9,VPS13A,PLCB1,FBXW11,TCF4,SATB2,TPCN2,TRIM2,USP32P1,ITGB3BP,TIAM1,TK2,SMUG1,RUNDC3B,RPL7L1,PLEKHH2,VLDLR,WIPF1,LAT2,CLDND1,ZNF19,MICU3,DPYSL5,DNALI1,NAV3,WNK3,PLSCR4,FBXO36,CASC15,JMJD1C,MSRB3,FAM198A" MicroRNA hsa-miR-21-5p:Functional MTI Functional MTI miRTarbase 4.03E-58 2.26E-54 1.95E-57 1.80E-56 127 611 "ESYT2,OSBPL1A,LCORL,PPFIA4,APAF1,APC,BCL7A,FUBP1,KRIT1,LONRF2,LRRFIP1,SRSF11,FOXN3,SOCS6,HECTD1,CLOCK,PREPL,HAPLN1,OSBPL3,SOCS5,APPL1,BOC,DOCK4,GAPVD1,DCAF8,ZFYVE16,TMEM170A,SCRN1,MYEF2,DDX46,DMD,DMTF1,DNM1L,EDIL3,ANKRD46,HIPK3,RASGRP1,PHF20L1,EGFR,EIF5,PLEKHA1,PAN3,ERBB2,FGF12,FOXO3,NBEA,RAPGEF6,SESN1,MALT1,SPIN1,FERMT2,GPD2,CNTRL,IL12A,STXBP5,LAMP2,LIFR,MBNL1,MEF2C,MEIS1,PPM1L,SAMD5,MYO9A,NEK1,OXTR,PFKFB2,ABCB1,SERPINI1,PIK3C2A,PIK3R1,PURG,PPARA,PRKAB2,SNRK,PTK2,PTX3,CEP97,USP47,REV3L,FIGN,PBRM1,ZNF532,MRAP2,AP1AR,SATB1,CPEB3,FBXO11,ST6GAL1,NUBPL,BTBD3,KANSL3,SIRT2,BTBD7,ATF7IP,TET1,ZNF667,SMARCA4,LIMCH1,FAM126B,FNBP1,MYCBP2,CDK19,ITPRID2,ELOVL4,SYNE2,VPS13A,ANKRD28,ATMIN,TRIM2,DICER1,TIAM1,TLR4,TP53BP2,TPM1,NR2C2,SGK3,CCDC14,ZBTB38,RNF103,NAV3,WNK3,EPM2A,RTN4,KAT6A,RSPRY1,NETO2,SOCS4" MicroRNA hsa-miR-711:mirSVR_lowEffct hsa-miR-711:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.18E-58 2.34E-54 2.02E-57 1.86E-56 177 1181 "ASPHD1,KDM5D,FMNL2,GALNT16,ADCY6,ADD2,KIAA1211,FAHD2CP,PCDH10,ZNF687,AMPD2,DPP10,EPB41L5,APOC2,CASK,LINC00173,MARK4,ATP6V1G2,ATP6V0A1,ADAM15,RGS11,BID,LDHD,RAB29,MYRF,RUNX1T1,CBFA2T2,ENTPD6,ZBED1,CPNE6,SLC4A8,TOGARAM2,ZNF385A,C2CD2,RGS6,SEC24C,PITPNM3,RUBCN,USP6NL,ARHGAP32,KATNAL2,CENPL,IP6K1,ELMO1,MFAP3L,POM121,GRIN3A,RPS6KL1,DYNC1I1,SLC25A18,DRP2,DTNA,DNM1L,SNX29,HIPK3,HEYL,SEMA3D,CELSR3,PHF20L1,MRO,GOLGA7,EIF4G1,EIF5,ELN,C3orf18,EIF1,VPS13B,MRPL10,DNAJC27,PTK2B,FGF11,SPSB4,WDR83,SPECC1,ZNF605,MEGF10,TUBA8,PCDH17,LNX1,GRB10,CIT,FAM19A2,RNFT2,SMAP1,C2CD4C,STXBP5,MAP4,MEIS1,MGAT3,SCAMP5,AFDN,ZNF862,NPTX2,NRCAM,NTRK3,TBC1D25,OGG1,DPY19L2P2,PCSK5,PLCB2,PLCL1,EPB41L4B,POLR2F,VSTM2L,KLK6,WDR25,NCR3LG1,BDNF-AS,PTK2,TTC13,RASGRF1,RET,GTDC1,RGS12,KCTD17,MRPS18A,SLC25A36,SPIN3,KIAA0895L,ABCA11P,KCNIP3,NCBP3,SALL1,ATXN2,CASC3,FAM102A,FERMT1,MYO18A,R3HDM2,WDR37,FAM81A,SLC11A1,ATF7IP,ARFGAP1,SMARCD3,INTS9,RCOR3,ANKRD36,ZSWIM8,ZC3H13,IQSEC2,CDK19,DDN,NFASC,ZC4H2,ERBIN,STAU1,ZSCAN29,PHLDB1,KANK1,SYN1,COBL,MTCL1,PJA1,SIN3B,USP22,SYNE1,NAT16,PUM2,SIK3,TLR4,TMPO,TRIO,SSBP2,VAV1,CLIP2,LGI4,ZNF24,NDRG4,MEIS3,MAP3K12,RNF103,PPP1R3F,PCBP4,EPM2A,TIGD6,KLHDC1" MicroRNA hsa-miR-1322:mirSVR_highEffct hsa-miR-1322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.83E-58 2.70E-54 2.33E-57 2.15E-56 139 737 "XKR4,HECW2,NME5,WDR35,LRCH2,SUGT1P4-STRA6LP-CCDC180,ARNTL,PLA2G4C,CDK13,MARK4,ZSCAN18,NCOA1,N4BP2L1,PROM1,BMP7,NAE1,CACNA1G,CACNA2D1,THSD7A,CBR1,KRIT1,CNOT8,NGEF,QKI,CNTN1,ABI3BP,FAM171B,CREM,CRHBP,AKAP12,HINFP,CSF1,SEC24C,GREB1,USP6NL,GAPVD1,SPOCK2,IP6K1,PITPNC1,DDX46,CHRDL1,GRIN3A,RAB39B,DNM1,USP3,DTNA,DNAJB6,GOLGA7,COPS4,GPHN,CDKL3,RRAGB,CLVS1,POLK,MEGF10,GALNT15,GABRB3,GALC,DISC1,NEU3,CBX1,LUZP2,GPD2,PLCD4,GRM8,IRAK3,BACH2,RBPJ,ITPKB,SLC35G1,KIF5A,MEIS1,POC1B,ZNF680,NTRK2,PCSK5,PDE1C,JAKMIP1,PLIN1,PURG,EXOSC10,MINDY2,EPDR1,CNTLN,PTK2,TMEM260,PTPN13,TMEM255A,RAP1GDS1,OXR1,ATP8B4,KCNIP1,TRAPPC13,AP1AR,S100B,SATB1,CSRNP3,SCN8A,CASC3,SH3BGR,SLA,CCDC88A,SMARCC2,ANKRD36,CMTR2,SP4,KDM4C,NECAB1,PLCB1,SYPL1,CAMTA1,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,TIMP4,FAM155A,WIPF1,ZNF781,PCDH20,ZNF45,CADM2,PRTFDC1,RNF103,ADAMTS9,PLSCR4,HRASLS,CASC15,JMJD1C,RNF170,NHSL1,KLHDC1,IFT88" MicroRNA hsa-miR-3165:mirSVR_lowEffct hsa-miR-3165:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.22E-58 2.92E-54 2.52E-57 2.32E-56 179 1208 "DGCR6,KCNH8,ACTN1,RNF150,BEND6,OLMALINC,SLC24A4,SORCS2,OSBPL8,ALCAM,UNC79,AMPD2,AMPH,SUGT1P4-STRA6LP-CCDC180,KCNAB2,BCAS1,RGS20,TMEM108,CHID1,ZNF583,CARMIL3,BBS2,NRP2,CA8,CACNB4,CALB1,CALB2,THSD7A,KALRN,HAP1,CAMK2A,P2RX6,L3MBTL4,LOC730101,CFL2,PPT2,QKI,ABI3BP,RCHY1,SLC35F1,CRMP1,CYBB,GAPVD1,HDAC4,EARS2,TM9SF4,AIF1L,PITPNC1,MFAP3L,SV2B,SGSM2,WDR20,CPEB2,MAMLD1,DNM1L,EBF1,EDNRA,HIPK3,FCF1,HEYL,EBI3,PLEKHA1,ING4,PAN3,COQ7,ABCA8,DLC1,RACK1,ZMYND10,FDFT1,FER,GTF2IRD2,PRKAG2,FLYWCH1,CAMKK2,KHDRBS3,ZNF559,DISC1,KIAA1841,NEU3,GCK,TCERG1,STARD3,ZNF638,ZNF782,DIDO1,PLCD4,CIT,RNF165,FAM107A,ADAMTS6,RASSF8,MAN1B1,BACH2,RBPJ,MAN2A2,AQP11,MATN3,MBD1,MBNL1,MIA2,MID1,MYO6,NRCAM,NTRK2,NUCB2,CHAMP1,PFKFB2,NLGN3,SEMA5B,PLCB2,PURG,POLR2F,PRKACB,GRAMD1C,CNTLN,PTPRB,NKAIN1,CCDC40,SH3TC2,RASGRF2,HKR1,RDX,ERI2,PRIMA1,KLHDC8A,ROBO2,CCDC25,NEK11,EPHA10,FAM192A,SCP2,SGK1,FBXO11,FNDC3A,SYBU,NUBPL,EPN2,CXXC4,SMARCD3,RCOR3,ANKRD36,SNAP25,MBD5,TMCC1,RBM34,ZSWIM8,KDM4C,PEG10,NFASC,SS18,ELOVL4,NSFL1C,KLHL7,NECAB1,ADAMTS17,SYN1,SYN2,SLC37A2,PJA1,TPCN2,SZT2,PCDHGA11,NAT16,HIF3A,CABIN1,TNS1,RASD2,ZNF346,ELP5,RUSC1,TTC3,RPL7L1,ZNF28,REEP1,ADAMTS9,TMEM63C,TTC7A,NETO1" MicroRNA hsa-miR-186-5p:TargetScan hsa-miR-186-5p TargetScan 5.93E-58 3.32E-54 2.86E-57 2.63E-56 134 685 "CLK4,NCKAP5,NDRG3,ADCY5,PTCHD1,INTS2,KCTD16,OSBPL8,C1QTNF3,CDC42BPA,MAP4K3,PARG,APBB2,CASK,CADPS,BACH1,MTMR3,CALB1,CAST,RUNX1T1,NOG,ARHGAP22,QKI,FHL5,ARMC8,LETMD1,AKAP5,NRG2,SEC31B,OSBPL3,CNTNAP2,RIMS2,CCDC144A,PYGO1,KIAA0408,MFAP3L,GRIN3A,DMD,CPEB2,PDCD6IP,FAM13A,EIF5,PAN3,MTSS1L,DNAJC27,DLC1,FECH,MEX3B,KHDRBS3,CELF1,FUT9,PCDH17,GPR12,GPR37,GRIA2,PARD3B,FICD,HAS2,HNMT,NEGR1,AGFG1,IRF8,IGF1,KNDC1,INSM1,METTL21A,KCNB1,KLHL23,CREG2,IPO5,LAMP2,MAP2,CHIC1,MITF,AFF1,MXI1,MYT1,IGSF11,PCSK1,PDE3A,PDE4D,GPR85,NLE1,FAM216A,LRP12,PPM1B,CEP41,DIRAS2,APTX,PID1,ERI2,GTDC1,FIGN,KLHL11,RORB,ELP2,HUNK,SALL1,SATB1,ATXN7,SCAF8,ASAP3,CPEB3,CHD9,FNDC3A,BTBD3,EPN2,EPC1,MBD5,FAM126B,PEG10,ARHGAP26,RBM26,LMO3,CLSTN2,NECAB1,ANKRD28,ANKRD12,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,CADM2,FZD3,RNF170,MSRB3,FXR1,JPH3" MicroRNA hsa-miR-3172:mirSVR_highEffct hsa-miR-3172:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.59E-58 3.69E-54 3.17E-57 2.92E-56 148 838 "ABHD6,FZD9,RNF150,OSBPL1A,CC2D2A,FAM135A,MYH7B,UPRT,INSYN2B,SGCE,CACNA1B,CAMK2G,LDB2,CERS5,SRSF11,CHN1,CPNE6,NRXN3,PLAA,MYL6B,MAP4K4,CNGA3,COL9A1,GAL3ST1,SMARCAL1,ZFP28,SLC35F1,SEC31B,CLOCK,C1QL2,GDA,CS,CSF1,CSF2RA,APPL1,UBXN2A,CTH,DCAF4,RUBCN,ARHGAP32,AIF1L,ARMCX4,SNAP91,SV2B,DLX1,DMD,DNM1L,GOLT1B,EDNRA,PHF20L1,SUGP2,EIF1,EMX2,RABEPK,IGSF6,ETV1,F5,FGF1,FGFR1,FHL1,MEX3B,TMEM107,ERGIC3,STAU2,B4GALNT1,ARFIP1,PCDH17,CRCP,GLYR1,TNRC6A,MSL3,GLUL,GPD1,PCLO,GRIK5,ATOH8,IRAK3,ELOVL5,HMGCL,ZNF491,ZDHHC15,SMAP1,EID2B,RBPJ,IL6R,LRRTM1,SMAD9,MAP6,IDNK,VWA2,NTRK3,PCSK1,TMEM38A,PMP22,SH3KBP1,NKAIN4,MAPK3,GDPD1,SNRK,PTPRD,ZNF793,ZMAT4,RNASEL,CARF,YY1AP1,ATAT1,CLIP1,TRAPPC13,FAM192A,SEMA6D,TNFRSF19,SHC4,CHD9,FHOD3,FAM81A,DHX30,SEPHS1,CCDC88A,SLC14A1,PDZD2,KDM4C,ZC3H13,TSPYL2,SEPT8,SULF2,SEPT3,NECAB1,SYN1,TCF4,SZT2,SYNE1,PCDHB9,SLC19A3,TNS2,CCDC173,ZMAT3,ARL10,TIMP4,CSMD1,PLEKHH2,BCL2L13,VGF,RICTOR,ZIC1,NDRG4,ZNF138,SIGLEC10,RNF170" MicroRNA hsa-miR-622:mirSVR_highEffct hsa-miR-622:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.34E-58 4.11E-54 3.53E-57 3.25E-56 143 783 "NDRG3,AXIN2,PWWP2A,KIAA1211,AMPH,DPP10,LRCH2,RGS20,ATP1B3,ATP2A2,BTK,JAZF1,CACNA1B,KALRN,PTBP2,NFS1,USP2,LARGE1,SLIT2,RAB28,QKI,AKAP7,SLC4A8,TBPL1,RGS6,CST3,APPL1,KIAA0586,DGKB,DGKG,DAPK1,EXOG,USP3,DTNA,E2F6,YAF2,PHF20L1,EYA1,ABCA8,FAM198B,FCGR1B,FKTN,FDFT1,ZNF589,POLK,SUCO,NELFCD,FOLR2,SMC2,ST6GALNAC3,AP4B1,DOT1L,SDCBP2,MEGF10,GALNT15,B4GALNT1,ZNF234,DISC1,GGT7,GHR,POLL,GRIA2,ATE1,PSIP1,RBPJ,IL6ST,METTL21A,KCNB1,KCNN3,LAMA2,STMN1,LMO2,ZNF667-AS1,MBD1,MBNL1,TM6SF1,MEIS1,MMP16,MYO7A,VWA2,DNHD1,SLC11A2,NUCB2,CLDN11,JAKMIP1,SEPT4,IRX1,PPP2R5E,MASP1,PIGG,PTK2,ZSCAN32,TMEM255A,USP47,SUSD4,RADX,KHDRBS2,MORC4,FBXW7,ATP8B4,SAFB,SALL1,SATB1,CSRNP3,LRFN5,PEAR1,SHC4,FNDC3A,FHOD3,DHX30,PKNOX2,SLC14A1,SLC22A4,MYO16,ZSWIM8,SP4,DBNDD2,RBM26,SS18,PRRC2C,PLCB1,TACC1,MTCL1,CAMTA1,KLHL4,CYB561A3,RIMBP2,PDSS1,TRO,ANKRD20A2,HIRA,CCDC14,WIPF1,ZBTB14,SPIRE1,SMARCAD1,SLC38A1,ADAMTS9,HPS4,FZD3,RTN4,PHTF2,ZDHHC20" MicroRNA "GCACTTT,MIR-106A:MSigDB" "GCACTTT,MIR-106A:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-106B:MSigDB" "GCACTTT,MIR-106B:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-20B:MSigDB" "GCACTTT,MIR-20B:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-519D:MSigDB" "GCACTTT,MIR-519D:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-17-5P:MSigDB" "GCACTTT,MIR-17-5P:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-20A:MSigDB" "GCACTTT,MIR-20A:MSigDB" MSigDB 8.04E-58 4.50E-54 3.85E-57 3.54E-56 121 555 "SLC24A4,ANK2,APBB2,SEMA4G,MARK4,RASL11B,ATP2B2,NRP2,MTMR3,JAZF1,KALRN,USP6,DLGAP2,CFL2,SOCS6,TAOK2,QKI,PCYT1B,AHCTF1,CLOCK,C2CD2,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,RASSF2,IP6K1,MFAP3L,FBXL5,SACS,USP3,DMTF1,DPYSL2,DNAJB6,E2F5,KMT5B,EIF4G2,ETV1,DNAJC27,EZH1,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,RAB30,TNRC6A,HAS2,HLF,KIF5A,CAMK2N2,MYCN,NBL1,CNOT4,OCRL,PIK3R1,CCSER2,PKD1,XRN1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,PTPRO,CEP97,OXR1,ZNF532,FAM102A,CHD9,FNDC3A,SYBU,WDR37,BTBD7,TET1,TMCC1,LMO3,CAMTA2,ITPRID2,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,MAP3K12,EMSY,SLC17A7,WNK3,FAM13C,MARCH8,PHTF2,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA hsa-miR-4289:mirSVR_highEffct hsa-miR-4289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-57 5.68E-54 4.85E-57 4.47E-56 144 796 "KCNH8,ABHD6,ACTN1,KLHL32,PWWP2A,INTS2,WDR35,ALCAM,FAM135A,ZFAT,PHF12,SEMA4G,TMEFF1,ADGRB3,DST,SYNJ2,KALRN,VXN,RUNX1T1,LDB2,CDH2,LRRFIP1,CFL2,RCBTB2,SOCS6,NDST3,PLAA,C4orf33,SLC4A8,HAPLN1,TRIM69,CS,MROH8,SEC24C,VCAN,ERC2,ZFYVE16,IP6K1,SPATA2,SPOCK3,GRIN3A,USP3,CPEB2,DTNA,EDN1,EDNRA,AASS,GOLGA7,RCAN2,FER,FGF14,ATP13A4,CELF1,GAD1,ERAP1,C15orf41,BRD8,KIAA1958,ZNF782,FERMT2,LILRB4,GRIA2,FAM19A2,ADAMTS6,RASSF8,SYNPO,ZDHHC15,ZNF546,KCND2,KTN1,SYTL4,MATN3,MEIS2,MN1,MXI1,MYT1,NCAM2,NEK1,SLC11A2,TBC1D25,OXTR,PDE4B,SLC10A4,PLCL1,PCDH18,PKIA,MASP1,CEP97,USP47,FAT4,MSANTD2,KLHDC8A,CARF,RPE,LRRK2,ABCA11P,CLIP1,SALL1,SEMA6D,SCN8A,SCP2,PPM1E,FERMT1,CPEB3,SLA,LIMS2,ZNF334,RCOR3,LIMCH1,MBD5,FAM126B,TRERF1,THSD1,PLCB1,SYT1,COBL,SATB2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,TIAM1,TLR4,RIMBP2,CSMD1,SMUG1,TRIO,EIF4ENIF1,USP1,VSNL1,CADM2,DNALI1,RNF103,WNK2,PARP11,FAM13C,DOCK8,RNF170,FRMD6" MicroRNA hsa-miR-3154:mirSVR_highEffct hsa-miR-3154:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-57 5.81E-54 4.96E-57 4.57E-56 159 968 "XKR4,KLHL32,BRAP,SPOP,PCDH10,FAM135A,NCOA1,ATP6V1G2,SYNJ1,ARHGEF7,CALB1,CBR1,USP2,CD38,ZBED1,ZMYM4,ARHGAP33,TIGD7,UBE2L6,ARHGEF6,CNTFR,SLC4A8,ZFP28,SEC31B,CLOCK,CRYBB1,GDA,CS,CSF2RA,ARHGEF10,CSNK1E,APPL1,PHF14,CCDC144A,HDAC9,GPRASP1,DCAF8,ZNF337,LIN54,SPOCK2,PABPC5,PITPNC1,C2CD2L,ZC3H11A,TMCC2,DMD,CPEB2,E2F5,EBF1,HIPK3,PAN3,EIF1,EPB41L2,GPHN,SRRM1,ETV1,PTK2B,POLR1B,FGF12,FHL1,IP6K2,NELFCD,NBEA,TMEM107,PRELID3A,STAU2,GABBR1,GALC,ERAP1,GGTA1P,MSL3,ZNF638,GP1BB,CCDC184,PLCD4,AP4S1,ADAMTS6,LRRCC1,ZNF678,MEIS1,AFDN,MN1,MYO9A,RTL5,NCF2,NINJ2,CNOT4,DNHD1,NUCB2,GLIPR1L2,PCDH9,PDPK1,PURG,PNMA3,PMP22,PPM1B,PPP2R2B,PPP3CA,MAPK7,MAPK9,RELN,KLK6,APTX,TMEM145,PID1,RAD17,DPF2,PRRT2,MORC4,GTDC1,RGS4,KCTD17,RIC8B,RNASEL,SETD5,EXD2,ATP8B4,ZNF568,ATXN2,CCDC88A,SLC11A1,SMARCC2,SMARCD3,RCOR3,ANKRD36,LIMCH1,SP2,DDN,CLASP2,ZC4H2,MPRIP,ZSCAN29,SYT1,ANKRD28,MTCL1,DMXL2,ZEB1,RPGRIP1L,FRYL,TMEM9,ACTR6,TMPO,NPL,ELP5,AMACR,TST,FAM155A,UBE3A,PLPPR2,VGF,KLC2,RICTOR,NDRG4,ZNF177,ZNF189,MEIS3,PRDM10,NHSL1,SENP7" MicroRNA hsa-miR-193a-5p:mirSVR_lowEffct hsa-miR-193a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-57 5.82E-54 4.97E-57 4.58E-56 181 1239 "ACADM,ABHD6,GALNT13,PWWP2A,BEND6,OLMALINC,AP2A2,PCDH19,ZNF578,TAOK1,PHF12,CDC14B,MARCH3,MARK4,SLC2A11,RNF182,RGS9,BCL7A,CFLAR,LDHD,CACNB4,CAMK2G,CAST,KRIT1,USP6,LRRFIP1,CNOT8,NRXN3,FAM189A2,SULT4A1,CNTFR,COL11A2,COX4I1,SMARCAL1,FAM171B,GDA,VAC14-AS1,PDE4DIP,SLITRK5,UBXN2A,FAM131B,GPRASP1,DAPK1,CHRDL1,NYAP1,DPH1,TOM1,GOLT1B,CELSR3,EBI3,EMX2,RASGRP2,SRRM1,ETV1,PTK2B,TAOK3,FDFT1,GTF2IRD2,POLR1B,FGF13,FGF14,IP6K2,AGAP3,SPECC1,FAM49B,NSG1,ALDH1L1,CYP46A1,DBF4,GLI2,MSL3,STON1,GRIA2,ADAMTS13,GRM2,ZBTB49,PADI2,VSIG4,SYNPO,HMGCL,NEGR1,TCEAL6,ZIC5,KNDC1,DISP2,SLC35G1,GATD1,STXBP5,ASPRV1,MAP2,MARK3,MEIS1,SRSF12,MMP16,MSR1,MYO5A,NELL2,OXTR,DPY19L2P2,CDK18,GNG2,PFKFB2,NLGN3,SDK2,PPARA,PPP5C,RASGEF1B,PRKACB,EPDR1,GRAMD1C,HYDIN,GDPD1,TMEM260,SUSD4,NWD1,RAP1GDS1,MSANTD2,ZDHHC4,RGS4,MRPS18A,SLC25A36,RIC8B,ZFHX4,ARMC5,CCDC102B,SNX22,NEK11,TNFRSF19,PPP4R3A,DHX30,ZNF430,SLC14A1,RCOR3,SNRPN,KDM4B,PDZD2,NMNAT2,GLT8D1,ZSCAN29,PHLDB1,SEPT3,NSFL1C,KLHL7,ANKRD12,TAL1,TBCEL,ATMIN,TPCN2,TRIM2,TCF12,CLASP1,SYNE1,SLC19A3,OBSL1,NSD1,VWCE,DICER1,GPR161,TIAM1,MTMR14,ERCC6L2,TRIO,TRO,PPIL6,RPRM,EIF4ENIF1,BCL2L13,PLPPR2,XRCC4,ZIC2,ZNF74,DPYSL5,LAMP5,SLC38A1,RNF103,TUBA1A,TMEM178A,HPS4,SLC17A7,FAM47E,JMJD1C" MicroRNA hsa-miR-16-5p:Functional MTI Functional MTI miRTarbase 1.04E-57 5.83E-54 4.97E-57 4.58E-56 205 1557 "ABCF1,ACTN1,AXIN2,FZD9,USP31,ADORA2A,PWWP2A,AP2A1,CASKIN1,HACE1,TBC1D14,AK2,TAOK1,TRMT9B,OGT,ARMC12,CDC14B,CASK,ARHGDIA,STK33,PCDHGB4,ZBTB10,EIF4G3,DOCK11,BCL7A,SYNJ1,FUBP1,MTMR3,CA8,CA12,CACNA2D1,CAMK2G,RUNX1T1,CCNT1,ENTPD6,LONRF2,CCPG1,TBRG4,CFL2,CLTC,CNN3,TBPL1,BAG4,ZFP28,CRHBP,NCOR2,CSNK1E,OSBPL3,SOCS5,PUM1,RUBCN,ARHGAP32,EARS2,RASSF2,ARMCX2,SPATA2,YTHDC1,ZC3H11A,DMD,DMPK,USP3,MED12,CPEB2,DMTF1,ACOT8,PDCD6IP,GOLT1B,FCF1,HEYL,EGFR,GOLGA7,EIF4G1,EIF5,PLEKHA1,EIF1,RAB9B,ZNF391,MRPL10,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,TUBB3,DLC1,FECH,SEC24B,FGFR1,VTI1B,PDLIM5,CAMKK2,MSANTD4,TPPP3,NEURL4,MTHFD2,ZNF559,RNPS1,RAB30,MSL3,ZNF638,RAB40B,GNAL,PTPRT,IRAK3,ATXN2L,ELOVL5,NEGR1,DHX35,MSL1,IDH3A,RBPJ,FAM69A,JAK2,KIF2A,KIF5A,IPO5,L1CAM,LAMP2,LIG4,SMAD1,MAP4,CHIC1,SCAMP5,MOV10,MYO5A,NACA,SLC11A2,OCRL,ZNF827,ETFRF1,PDE4D,PIK3R1,NLE1,PLEC,PRIMPOL,PSAT1,PRKAB2,CNNM2,PTPRD,TMEM255A,ROGDI,RBBP6,RNASEL,ZFHX4,RNH1,SETD5,EXD2,YY1AP1,FBXW7,SALL1,SARS,SBF1,HSPA4L,CPEB3,DHX30,KANSL3,SLC12A2,EPC1,SMARCA4,TTC17,ANKRD36,TMCC1,FNBP1,GLT8D1,DDN,LARP4,STAU1,KANK1,SUPT5H,PRRC2C,DNAJC9,SYPL1,MMS19,TAF9,FAM208A,FBXW11,CLASP1,DOCK9,FRYL,CYB561A3,DICER1,ZMAT3,ARL10,CABIN1,TPM2,NR2C2,RUNDC3B,HSPBP1,TUBB2A,SGK3,UBE2H,SLC35A4,UGT8,WIPF1,CLIP2,KLC2,RICTOR,XPO1,SLC38A1,TUBA1A,WNK3,PLSCR4,RTN4,ACTR3B,AAAS" MicroRNA "CTTTGTA,MIR-524:MSigDB" "CTTTGTA,MIR-524:MSigDB" MSigDB 1.08E-57 6.03E-54 5.13E-57 4.73E-56 105 409 "ADD1,UNC79,EP400,MAP4K3,FAM131A,PPFIA3,IGDCC4,MARK4,NCOA1,CCAR2,ATP2B2,JAZF1,MYRF,KALRN,LRBA,DCLK1,ARHGAP33,CDO1,CACNA2D2,FOXN3,QKI,TMEM184B,HECTD1,CNR1,ARMC8,CNRIP1,CDC42BPB,CREM,CRHBP,CRMP1,LRRC3B,CSNK1E,PPP1R16B,PUM1,DBN1,DLX1,CPEB2,GOLT1B,EDN3,KLHL5,CELSR3,PHF20L1,MBNL2,EIF5,EPB41,RCAN2,PPP1R1B,SEC24B,OLFM1,UBE2E3,NBEA,CELF1,CPLX2,SESN1,PCDH17,STARD3,GNAO1,GRIA2,ADAMTS6,KCNQ3,KIF5A,LAMP2,LRP1B,MEF2C,SCAMP5,MITF,MXI1,NFIX,IGSF11,PAX6,PCDH9,NLGN3,ZNF655,PPM1B,PPP3CA,PPP5C,DIRAS2,PSD,PTPN13,PTPRE,GTDC1,ATXN2,CPEB3,BTBD7,CPEB4,PDZRN3,USP33,SOX11,SP4,LMO3,ERBIN,VPS13A,ASTN2,FBXW11,TBL1X,PUM2,ZNF106,CBX5,TRPS1,MTCH1,ZIC1,SMARCAD1,NAV3,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-103-as:mirSVR_lowEffct hsa-miR-103-as:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-57 6.46E-54 5.50E-57 5.06E-56 177 1189 "DGCR6,KCNH8,NCKAP5,XKR4,NDRG2,CCDC85A,GALNT13,ADD1,ADD2,TXNDC16,HFM1,SRPX,UNC79,CDC42BPA,LRCH2,PKP4,APC,PPP4R4,SPTBN4,CDK13,NCOA1,ATP1B3,DPY19L3,ADAM23,DST,BTK,SCAPER,C5,CACNA1B,DDR1,CACNB4,CAMK2A,CAMK2G,SLC25A14,CBFA2T2,ZMYM4,CLGN,CFL2,FOXN3,MYL6B,FHL5,ARMC8,COX4I1,CLOCK,CRY2,LRIG1,PDE4DIP,KIAA0040,RIPOR2,ZFYVE16,SCRN1,ARMCX4,MFAP3L,EXOG,USP3,DNAJB6,E2F5,FAM13A,EIF4G2,ELN,EPHB1,STX2,IGSF6,F5,SCML2,FECH,FER,FGFR1,UBE2E3,EFCAB2,WDR83,HVCN1,ERGIC3,DLL3,ABLIM2,OGA,DISC1,CSDC2,GGTA1P,GGT7,LYVE1,COPS8,GLI2,TNRC6A,STARD3,LUZP2,DCLK2,PRUNE2,LPAR4,PLCD4,AP4S1,FAM107A,MAP4K5,FRMD3,GABARAPL2,MSL1,STXBP5,LIMS1,SYTL4,HECTD2,MARK1,COL28A1,BLOC1S2,VWA2,PFKFB2,ZDHHC8,XRN1,PRIMPOL,ING3,PPM1B,PPP2R5E,RASGEF1B,MAPK9,TRIM68,REV3L,PRRT2,GTDC1,FIGN,SLC25A36,ZFHX4,TMLHE,GSTCD,ROBO2,RYR3,SCP2,KIF21A,FRMPD1,MYO18A,AMBRA1,NUBPL,WDR37,ABLIM3,PREX2,WDR47,CCDC88A,SLC14A1,LMBRD1,ZSWIM8,SP4,MYCBP2,KDM4C,ZNF423,SPTB,SPART,NFASC,SAMSN1,LARP4,NKAIN2,CEP68,SULF2,SYT1,COBL,TBCEL,ATMIN,ZEB1,SYNE1,HEY1,BHLHB9,TMPO,NPL,C9orf85,SYNPO2,STXBP4,RPL7L1,FAM155A,FLRT2,USP1,TOM1L2,LYPD6,ZNF177,SLC38A1,PHTF2,RSPRY1,RNF170,FXR1,LAS1L,SENP7" MicroRNA hsa-miR-448:TargetScan hsa-miR-448 TargetScan 1.21E-57 6.79E-54 5.77E-57 5.31E-56 116 509 "C3orf14,ADD1,HECW2,KCTD16,DOC2A,APBB2,APC,ARNTL,PCDHGB4,ATP2B2,LDLRAD4,CABP7,CCNT1,DCLK1,CFL2,IGLON5,ARHGEF6,IQCK,ARMC8,BAG4,HAPLN1,CCDC144A,LIN54,BRINP1,MYEF2,KLHL3,DMD,CPEB2,DTNA,EBF1,RASGRP1,KLHL5,MBNL2,RGS17,GPHN,ETV1,SCML2,FOXO3,NBEA,ATP2C1,DOT1L,GABRB3,KDM2B,FERMT2,GPR37,GRIK4,FRMD5,BACH2,KCNB1,KCND1,KCNK3,KCNQ3,KIF2A,KPNA5,LIMS1,PAXBP1,HECTD2,MEF2C,MITF,MYH3,MYO5A,NCAM2,NFYA,PCDHGC3,PCDH8,PDE4D,PIK3R1,CCSER2,MTRF1L,PRKAB2,PTPRE,CEP97,RAD51D,OXR1,RASGRF2,ERI2,GTDC1,KIF7,ROBO2,RORB,SATB1,FAM102A,NLGN1,ABLIM3,PKNOX2,ARHGEF40,BTBD7,NMNAT2,HECW1,CDK19,RBM26,NFASC,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,CRTC1,CBX5,FAM124A,FLRT2,RICTOR,KCNK12,CADM2,RGS7BP,FZD3,FXR1,GAN,JPH3" MicroRNA hsa-miR-556-5p:mirSVR_highEffct hsa-miR-556-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.66E-57 9.27E-54 7.87E-57 7.25E-56 162 1007 "RALGAPA1,XKR4,NDRG3,ADRA1D,KCTD16,WDR35,OGT,LCORL,PKP4,APC,DDO,NUMB,ADGRB3,KSR1,DST,ST3GAL5,CALB2,RUNX1T1,CLDN10,NDST3,NGEF,FBXO7,CNTN1,AKAP5,SLC4A8,SEC31B,SEC24C,CSNK1G3,PHF14,PUM1,CYBB,DOCK4,ARHGAP32,GAPVD1,TBC1D5,HEPH,DDX46,SACS,FAM107B,NYAP1,CDON,DMTF1,DPYSL2,ECM2,DNAJB6,DNM1L,ANKRD46,TMTC1,FSD1L,OPTN,FAM13A,PHF20L1,ASB3,PAN3,SRRM1,CDKL3,GMPR2,F8,RACK1,ZSCAN30,SEC23B,RGPD5,UFM1,STAU2,DOT1L,CHL1,GABRG2,SULT1C4,WASHC2A,ZNF276,RAB30,TNRC6A,MAP7D2,GPD2,GUCY1B1,AGBL5,NEGR1,HSF2,LRRCC1,ITPKB,JAK2,KHK,CREG2,MAN2A2,MAT2A,MBNL1,MN1,COMMD5,MXI1,NF1,SLC11A2,NUCB2,CLDN11,PDE4D,STRN3,EXOSC10,MINDY2,PPP2R5E,VPS13C,TMEM104,CNTLN,TMEM260,RAP1GDS1,RDX,RET,ZFHX4,SETD5,EXD2,CARF,MRAP2,NEK11,ADAL,MAP6D1,LRRK2,ZNF568,FNDC3A,SLC4A3,SLC14A1,LIMCH1,CMTR2,FNBP1,KDM4C,ZC3H13,STXBP1,MTCL1,TBCEL,TBL1X,SATB2,RPGRIP1L,USP22,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,ERCC6L2,TMPO,CSMD1,C9orf85,RUNDC3B,ANKRD20A2,TSC1,CLHC1,ZNF610,UGT8,AGMO,CELF4,RNF103,PPP1R3F,FIP1L1,WNK3,PDSS2,SMIM8,PHTF2,CASC15,NLRP3,NETO2" MicroRNA hsa-miR-4298:mirSVR_highEffct hsa-miR-4298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-57 1.11E-53 9.44E-57 8.69E-56 141 767 "RALGAPA1,KCNH8,KLHL32,CCDC85A,GALNT13,BRAP,PWWP2A,UPRT,VAT1L,AQP6,CCAR2,ATP2B2,ZNF583,ADGRB2,NRP2,DST,ARHGEF7,CALB1,SYNGR3,CD38,ENTPD6,LRRFIP1,CDO1,PPT2,SUMF2,ABI3BP,HINFP,ANKRD44,GDA,RUBCN,GPRASP1,ARHGAP32,RIPOR2,ZBTB24,ALKBH8,RAB39B,DYNC1I1,SLC12A6,DTNA,E2F6,EDN1,YAF2,APH1A,EPHB1,NCALD,F5,F8,ARMCX1,PTK2B,FCGR3A,FGFR1,SCARA3,SLC37A3,SPECC1,NEURL4,IQGAP2,DISC1,RAB30,TNRC6A,GLUL,ZNF638,LUZP2,PRUNE2,GRIA2,GRM8,FAM19A2,MIER3,NKD1,KIAA1755,FAM69A,LRRTM1,KCNQ3,STMN1,LIG4,MBD1,TM6SF1,LRP1B,KITLG,COL28A1,NEXMIF,NME4,VWA2,CNOT4,PCDH9,DUSP26,SNX10,PLCL1,SAMD9,VPS13C,OXR1,HKR1,GSTCD,GLDN,ABCA11P,NCBP3,SEC14L1,SH3GL3,HKDC1,FBXO11,SYBU,SEC31A,FAM81A,BTBD3,ATF7IP,ZNF667,INAVA,MAPKBP1,ANKFN1,KDM3A,KDM4C,CDK19,NKAIN2,MPRIP,SULF2,SEPT3,SYN1,SYN2,SYT1,FAM208A,TCEA1,SYNE1,SLC19A3,OBSL1,CYB561A3,AP4E1,RASD2,METTL3,TRPS1,RUSC1,TSC1,HSPBP1,VSNL1,PCDH20,ZNF45,TMEM237,MAP3K12,SIGLEC10,FAM47E,DOCK8,ST7,PHTF2" MicroRNA hsa-miR-548k:PITA hsa-miR-548k:PITA_TOP PITA 2.12E-57 1.19E-53 1.01E-56 9.25E-56 117 521 "FMNL2,USP31,PWWP2A,ZNF608,KLHL13,TBC1D14,ZNF578,TAOK1,MARCH4,MAP4K3,PKP4,CDC14B,CDK13,ZBTB10,SLC4A4,DOCK11,FUBP1,WASF1,L3MBTL4,NUMBL,CHN1,QKI,ARMC8,GDA,CSNK1E,CSNK1G3,ERC2,HDAC4,MATR3,PABPC5,HS3ST2,DYNC1I1,DOCK2,DPYSL2,GOLT1B,YAF2,KMT5B,COPS4,PAN3,ERBB4,EYA1,ACSL4,SCML2,FGF13,MEX3B,NBEA,CSPG5,OGA,CHL1,GABRG2,SESN1,GHR,RNPS1,GRIA2,PTPRT,FAM19A2,ADAMTS6,MAP4K5,MIER3,HSF2,CELF5,SMAP1,KCND2,SMAD1,MEF2C,KITLG,ZNF680,NFE2L2,NOVA1,GPR137C,LRP12,PPP3CA,PTPRD,ZNF493,SETD5,ALG9,ROBO1,RORB,HUNK,RTN1,SEMA6D,SATB1,CPEB3,CHD9,FAM214B,CCDC88A,CPEB4,PDZRN3,SP2,SP4,CDK19,RBM26,CLASP2,ITPRID2,SS18,TTBK2,ZC3H4,CAMTA1,TAL1,DMXL2,SATB2,DOCK9,C18orf54,ZNF106,TIAM1,NR2E1,RIMBP2,TRPS1,FLRT2,ZIC1,ZNF711,CELF4,EMSY,WNK3,FAM13C,KAT6A,CPNE4" MicroRNA hsa-miR-96:mirSVR_highEffct hsa-miR-96:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.50E-57 1.40E-53 1.19E-56 1.09E-55 155 927 "ASPHD1,KDM5D,XKR4,KLHL32,ADCY6,SLC24A4,KIAA1324,C1QTNF3,ABCD2,ALK,AMPD3,LRCH2,FGD2,C6orf89,UPRT,VAT1L,STK33,DPY19L3,ADGRB3,MIR9-3HG,DST,ARHGEF7,MTMR2,JAZF1,CACNB4,THSD7A,LDB2,SEPT7,MAGI1,TIGD7,CACNA2D2,NDST3,CLTC,LY86,CNN3,COL9A1,MYRIP,LRIG1,ERC2,APPL1,HDAC9,ARHGAP24,TM9SF4,DGKG,ZC3H11A,PLPPR4,E2F5,EDNRA,FAM13A,PHF20L1,EGR3,EIF4G2,PLEKHA1,CALCRL,GPHN,SRRM1,ZNF585B,FDFT1,FHL1,FOXF2,NOP56,SMC2,FAM49B,ST6GALNAC3,NSG1,FYN,GABRG2,B4GALNT1,DISC1,KIAA1841,SPIN1,ZNF782,GPR12,KAT7,RASSF8,HAS2,ZHX1,ELOVL5,C2orf72,NME9,KTN1,TM6SF1,MITF,TAGLN3,LAYN,MYO6,HNRNPM,NF1,NOVA1,DNHD1,GPR137C,PCDH9,PCSK1,PCSK5,PFKFB3,PIK3C2A,FAM216A,PDZRN4,MAPKAP1,LRP12,SCHIP1,EPB41L4B,SH3KBP1,PPP2R5E,PTPRB,CEP97,RASGRF2,ZMAT4,RIC8B,ZFHX4,BAALC,MCMBP,MRAS,SUPT20H,SH3GL3,FHOD3,SYBU,DZIP1,NUBPL,FAM81A,PPP4R3A,BTBD3,RCOR3,IFT122,MYO16,KDM4C,CLASP2,POGZ,SS18,TTBK2,ADHFE1,KLHL7,JMJD6,FBXW11,TBL1X,ZEB1,PCDHB6,SIK3,FAM200B,DICER1,TIMP4,TPM1,RUNDC3B,DCBLD1,RPL7L1,UBE3A,VLDLR,TRIM9,TMEM198,ZFAND5,NAV3,PDSS2,JMJD1C,NETO2,GAN" MicroRNA hsa-miR-601:mirSVR_lowEffct hsa-miR-601:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.03E-57 1.69E-53 1.43E-56 1.32E-55 153 905 "SYS1,GALNT16,OLMALINC,RTL9,USP35,ALCAM,TRMT9B,LGR5,ZFYVE28,CADPS,CDK13,MARCH3,ZBTB10,TTLL9,LINC00847,NRP2,DST,CAMK2A,CAST,ARHGEF25,CD38,CFL2,COPB2,ASIC3,CHN2,TAOK2,AKAP6,TBPL1,ZNF385A,CDC42BPB,CLIP3,AATK,CST3,KIAA0040,PHF14,BOC,GAPVD1,DCAF8,LONRF1,TBC1D5,MATR3,INTS1,ARMCX2,SPOCK3,HS3ST2,DPH1,DNAJB6,AASDH,SNX29,HIPK3,FAM13A,TNK2,CALCRL,EMX2,EPB41,FGF11,MSANTD4,B4GALNT1,DISC1,GATM,NEU3,TCERG1,COPS8,ZNF638,GNAO1,ADGRA3,GP1BB,LILRA2,GPR12,TMEM121B,ZBTB45,IRAK3,GABARAPL2,AGBL5,HNMT,SHISA6,GAREM2,INPP5B,KCND2,KCNJ16,NCOA7,CLEC18A,MARK3,NRBP2,SAMD14,NEXMIF,NTRK2,ZNF713,PCDH9,PDE1B,PFKFB3,MTRF1L,PURG,ING3,DIRAS2,KLK6,CNNM2,BCAS3,CNTLN,CCDC40,IQSEC3,GAL3ST4,TRIM68,FIGN,ZDHHC4,ZFHX4,ZNF532,ALG9,PNMA8A,CCDC102B,SPIN3,SGSM1,ATAT1,ZNF331,SEMA6D,ZFP30,SH3GL3,ARX,FBXO11,WDR47,SLC9A5,INAVA,PDZD2,MYCBP2,ERC1,ZBTB43,NFASC,ITPRID2,TTBK2,PRRC2C,PLCB1,SYN1,C12orf76,TACR1,KLHL4,TCEA1,DMXL2,CUX2,SYNE1,HIF3A,C9orf85,PPIL6,TTC3,CLHC1,RPL7L1,EIF4ENIF1,VLDLR,XPO1,XRCC4,MDH1B,ITM2C,TMEM63C,ADAMTSL3" MicroRNA "TGTTTAC,MIR-30A-5P:MSigDB" "TGTTTAC,MIR-30A-5P:MSigDB" MSigDB 3.86E-57 2.16E-53 1.82E-56 1.67E-55 119 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B2,NRP2,KSR1,SLC25A14,CARS,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,PLPPR4,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,EPB41,RASL12,EXTL2,AMOTL2,MEX3B,CAMKK2,IP6K3,PCDH17,TTBK1,TNRC6A,GNAO1,TMEM121B,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,HLF,ELOVL5,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,PDE4D,TMOD2,CEP41,WBP1L,ANKHD1,PTPN13,USP47,PRRT2,SBF1,SCN8A,FRMPD1,FNDC3A,FHOD3,NLGN1,BTBD7,CPEB4,TMCC1,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,SATB2,SIRT1,RIMBP2,R3HDM1,C9orf85,TRPS1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,MAP3K12,STOX2,ADAMTS9,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30B:MSigDB" "TGTTTAC,MIR-30B:MSigDB" MSigDB 3.86E-57 2.16E-53 1.82E-56 1.67E-55 119 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B2,NRP2,KSR1,SLC25A14,CARS,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,PLPPR4,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,EPB41,RASL12,EXTL2,AMOTL2,MEX3B,CAMKK2,IP6K3,PCDH17,TTBK1,TNRC6A,GNAO1,TMEM121B,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,HLF,ELOVL5,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,PDE4D,TMOD2,CEP41,WBP1L,ANKHD1,PTPN13,USP47,PRRT2,SBF1,SCN8A,FRMPD1,FNDC3A,FHOD3,NLGN1,BTBD7,CPEB4,TMCC1,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,SATB2,SIRT1,RIMBP2,R3HDM1,C9orf85,TRPS1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,MAP3K12,STOX2,ADAMTS9,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30C:MSigDB" "TGTTTAC,MIR-30C:MSigDB" MSigDB 3.86E-57 2.16E-53 1.82E-56 1.67E-55 119 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B2,NRP2,KSR1,SLC25A14,CARS,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,PLPPR4,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,EPB41,RASL12,EXTL2,AMOTL2,MEX3B,CAMKK2,IP6K3,PCDH17,TTBK1,TNRC6A,GNAO1,TMEM121B,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,HLF,ELOVL5,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,PDE4D,TMOD2,CEP41,WBP1L,ANKHD1,PTPN13,USP47,PRRT2,SBF1,SCN8A,FRMPD1,FNDC3A,FHOD3,NLGN1,BTBD7,CPEB4,TMCC1,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,SATB2,SIRT1,RIMBP2,R3HDM1,C9orf85,TRPS1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,MAP3K12,STOX2,ADAMTS9,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30D:MSigDB" "TGTTTAC,MIR-30D:MSigDB" MSigDB 3.86E-57 2.16E-53 1.82E-56 1.67E-55 119 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B2,NRP2,KSR1,SLC25A14,CARS,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,PLPPR4,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,EPB41,RASL12,EXTL2,AMOTL2,MEX3B,CAMKK2,IP6K3,PCDH17,TTBK1,TNRC6A,GNAO1,TMEM121B,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,HLF,ELOVL5,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,PDE4D,TMOD2,CEP41,WBP1L,ANKHD1,PTPN13,USP47,PRRT2,SBF1,SCN8A,FRMPD1,FNDC3A,FHOD3,NLGN1,BTBD7,CPEB4,TMCC1,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,SATB2,SIRT1,RIMBP2,R3HDM1,C9orf85,TRPS1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,MAP3K12,STOX2,ADAMTS9,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30E-5P:MSigDB" "TGTTTAC,MIR-30E-5P:MSigDB" MSigDB 3.86E-57 2.16E-53 1.82E-56 1.67E-55 119 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B2,NRP2,KSR1,SLC25A14,CARS,SYNGR3,SEPT7,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,PLPPR4,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,EPB41,RASL12,EXTL2,AMOTL2,MEX3B,CAMKK2,IP6K3,PCDH17,TTBK1,TNRC6A,GNAO1,TMEM121B,GRB10,GRIA2,CIT,RNF165,ADAMTS6,MAN1B1,HLF,ELOVL5,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,PDE4D,TMOD2,CEP41,WBP1L,ANKHD1,PTPN13,USP47,PRRT2,SBF1,SCN8A,FRMPD1,FNDC3A,FHOD3,NLGN1,BTBD7,CPEB4,TMCC1,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,SATB2,SIRT1,RIMBP2,R3HDM1,C9orf85,TRPS1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,MAP3K12,STOX2,ADAMTS9,PHTF2,FRMD6" MicroRNA hsa-miR-548v:mirSVR_highEffct hsa-miR-548v:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.88E-57 2.17E-53 1.83E-56 1.69E-55 141 771 "RALGAPA1,KCNH8,ACADM,CLK4,AXIN2,TXNDC16,ALCAM,FAM135A,LRCH2,PKP4,IGDCC4,ATP2B2,SYNJ1,MTMR2,CALM1,PTBP2,NFS1,PRC1,ZNF501,MAGI1,CFL2,CHN1,SULT4A1,LY86,CREM,CS,SNCAIP,ARHGEF10,PDE4DIP,DZIP3,PHF14,ZFYVE16,TM9SF4,IST1,IP6K1,JAKMIP2,SPOCK3,DPP6,RCAN1,ARRDC4,DNM1L,TSPAN5,EDNRB,SEMA3D,FRY,PLEKHA1,MRNIP,ZNF461,OLFM1,STAMBP,CGREF1,MSANTD4,GABRA3,ZNF234,MTHFD2,MSTN,TNRC6A,ZNF638,KCNMB4,TDRKH,PRDM5,ZBTB49,HMGCR,HNF4G,IGFBPL1,DHX35,SMAP1,KIT,STMN1,NCOA7,MARK1,MEIS2,KCTD6,ZNF680,NOVA1,GLIPR1L2,PCSK1,RETREG1,GPSM2,KANSL1,PRKACB,PKIA,HYDIN,RELN,ZIK1,EML5,PTPRO,FAM66C,REV3L,RFX3,SLC25A36,RIC8B,RTN1,SEMA6D,SATB1,LRFN5,COPZ1,FERMT1,FHOD3,SLC8A1,BTBD7,KIF13A,SNRPN,GLT8D1,HECW1,KDM4C,TEX2,CDK19,NECAB1,PLCB1,COBL,C12orf76,SIN3B,TCF12,SYNE1,PCDHB15,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,ITGB3BP,KAT6B,P2RY12,CLDND1,ZIC1,TRIM9,AGMO,MKRN3,TMEM198,DPYSL5,STOX2,CIAPIN1,KAT6A,RSPRY1,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-3126-3p:mirSVR_highEffct hsa-miR-3126-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.02E-57 2.25E-53 1.89E-56 1.74E-55 128 633 "SYN3,ADD2,DPY19L2P4,KIAA1324,AK2,AMPD3,TMEM108,ATP1B3,ATP2A2,ZNF582,N4BP2L1,DST,ARHGEF7,CASTOR3,NFS1,ARHGEF1,DIS3L,ARMC8,SLC35F1,CREM,ANKRD44,PDE4DIP,FAM169A,DOCK4,TMEM170A,GIT2,YTHDC1,ALKBH8,DYNC1I1,DTNA,EDN1,FCF1,KLHL5,COPS4,EPB41L2,DENND4A,NSRP1,KAT8,GORAB,FER,FGFR1,NBEA,SMC2,STAU2,TRAF3IP2,KIAA1841,TCERG1,HPGDS,DIDO1,PLCD4,GRM8,ZHX1,NXPH3,VSIG4,HNMT,DHX35,IRF8,MSL1,KIF2A,LAMP2,ZFYVE27,MAP2,MARK1,ZNF680,NRBP2,N6AMT1,MYO7A,P2RY13,NCAM2,NTRK2,NUCB2,IGSF11,SERPINI1,EPB41L4B,POLR2F,DRAM2,MINDY2,MASP1,WBP1L,SNRK,EML5,USP47,OXR1,RFX3,ROBO1,PCMTD2,ATP8B4,GLDN,MEG3,SEMA6D,ANKRD6,WDR37,ARHGEF40,SLC12A2,USP33,KDM4C,CDK19,TROVE2,SEPT8,VPS13A,TACR1,DNMBP,SIN3B,SATB2,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,ELP5,RPL7L1,TRIM9,LYPD6,CELF4,MFF,MPPE1,PLSCR4,UBE3B,PHTF2,JMJD1C,AP3B2,SENP7" MicroRNA hsa-miR-494:PITA hsa-miR-494:PITA_TOP PITA 5.38E-57 3.01E-53 2.53E-56 2.33E-55 122 574 "XKR4,ADCY6,USP31,ESYT2,INTS2,KLHL13,PCDH19,HACE1,OSBPL6,FAM135A,LCORL,ARNTL,ZBTB10,SLC4A4,ARHGEF7,CAST,CH25H,SOCS6,CHN1,CNN3,CNR1,AKAP7,CLOCK,RBM39,SOCS5,DZIP3,APPL1,DBN1,JAKMIP2,MFAP3L,ZC3H11A,RHOBTB1,DMD,EDN1,YAF2,FAM13A,MBNL2,KMT5B,EGR3,EIF5,PAN3,RCAN2,ERBB4,ACSL4,TAOK3,SCML2,SEC24B,FHL1,SYNCRIP,NBEA,STAU2,PPARGC1A,TNRC6A,RAB40B,PRRC2B,PCLO,ADAMTS6,HAS2,ELOVL5,KIT,IPO5,MAT2A,LRP1B,MN1,MSI1,NEXMIF,ZC3H12B,CNOT4,NOVA1,PCSK1,PRTG,PDE4B,PPP2R2B,CEP41,PTPRB,TMEM255A,MSANTD2,PBRM1,ZFHX4,ZNF532,RPL15,RASA3,CHD9,FBXO11,FHOD3,WDR37,TET1,MBD5,SOX11,SP4,NMNAT2,KDM4C,CEP68,STAC2,SYNE2,PLCB1,SYPL1,TACC1,MTCL1,CAMTA1,PHF24,SIRT1,ZFPM2,TIAM1,ERCC6L2,TRPS1,SGK3,FAM155A,WIPF1,ZIC2,REEP1,TMEM237,POLR3H,LAMP5,SLC30A4,EVI5,RNF103,KAT6A,HNRNPA3,DPF3,RNF146,SOCS4" MicroRNA hsa-miR-374b-5p:TargetScan hsa-miR-374b-5p TargetScan 5.88E-57 3.29E-53 2.76E-56 2.55E-55 119 545 "ABR,ACTN1,ARHGAP20,PCDH10,APC,GAS7,PDE8B,NCOA1,ATP1A1,ATP2B2,LDLRAD4,CA12,DCLK1,NOG,NUMBL,CNOT8,ABCG2,QKI,HECTD1,IQCK,AKAP6,NRG2,HAPLN1,RNF14,FAM169A,KIAA0408,HDAC9,PITPNC1,MFAP3L,DMD,RCAN1,EDIL3,SEMA3D,MBNL2,PLXNC1,EIF4G1,EIF4G2,DENND4A,NRN1,ABCA8,FECH,MED12L,FGF12,MEX3B,SEC23B,PSD2,APOPT1,MPP6,AHDC1,PPARGC1A,GPR75,GPT2,FAM19A2,RASSF8,HLF,SCIN,METTL21A,KCNN3,KTN1,L1CAM,LSAMP,MAP2,MBNL1,MEIS1,AFF1,MYO9A,NFIX,NOVA1,NPTX2,OCRL,PAX6,PDE3A,PDE4A,PDE4D,PDPK1,FAM216A,PURG,PPP2R2C,PKIA,PTPRG,GTDC1,RFX3,PRIMA1,RORB,HUNK,SATB1,CSRNP3,ATXN7,SCN2B,FNIP1,DZIP1,ARHGEF40,BTBD7,CPEB4,MBD5,PDZD2,ERC1,IQSEC2,CDK19,POGZ,LARP4,ANKRD12,ATMIN,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,CSMD1,DOK6,CADM2,PPP1R3F,RGS7BP,FAM13C,KAT6A" MicroRNA hsa-miR-374a-5p:TargetScan hsa-miR-374a-5p TargetScan 5.88E-57 3.29E-53 2.76E-56 2.55E-55 119 545 "ABR,ACTN1,ARHGAP20,PCDH10,APC,GAS7,PDE8B,NCOA1,ATP1A1,ATP2B2,LDLRAD4,CA12,DCLK1,NOG,NUMBL,CNOT8,ABCG2,QKI,HECTD1,IQCK,AKAP6,NRG2,HAPLN1,RNF14,FAM169A,KIAA0408,HDAC9,PITPNC1,MFAP3L,DMD,RCAN1,EDIL3,SEMA3D,MBNL2,PLXNC1,EIF4G1,EIF4G2,DENND4A,NRN1,ABCA8,FECH,MED12L,FGF12,MEX3B,SEC23B,PSD2,APOPT1,MPP6,AHDC1,PPARGC1A,GPR75,GPT2,FAM19A2,RASSF8,HLF,SCIN,METTL21A,KCNN3,KTN1,L1CAM,LSAMP,MAP2,MBNL1,MEIS1,AFF1,MYO9A,NFIX,NOVA1,NPTX2,OCRL,PAX6,PDE3A,PDE4A,PDE4D,PDPK1,FAM216A,PURG,PPP2R2C,PKIA,PTPRG,GTDC1,RFX3,PRIMA1,RORB,HUNK,SATB1,CSRNP3,ATXN7,SCN2B,FNIP1,DZIP1,ARHGEF40,BTBD7,CPEB4,MBD5,PDZD2,ERC1,IQSEC2,CDK19,POGZ,LARP4,ANKRD12,ATMIN,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,CSMD1,DOK6,CADM2,PPP1R3F,RGS7BP,FAM13C,KAT6A" MicroRNA hsa-miR-642:mirSVR_highEffct hsa-miR-642:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.70E-57 4.31E-53 3.61E-56 3.33E-55 159 982 "SYS1,XKR4,RNF150,PCDH19,RTL9,PCDH10,PHF12,SUGT1P4-STRA6LP-CCDC180,UPRT,BCAS1,RGS20,PLA2G4C,ATP6V0A1,ADGRB3,NRP2,PROM1,DST,CASTOR3,KALRN,CDH2,PPT2,CLCN3,MAP4K4,ENTPD4,GDA,SNCAIP,LRIG1,SUSD5,FAM169A,GREB1,RUBCN,BOC,MYADM,GAPVD1,ARHGAP24,TBC1D5,KCTD8,DGKB,TMEM170A,SPOCK2,YTHDC1,JAKMIP2,ALKBH8,GRIN3A,PDCD6IP,GOLT1B,E2F5,EPB41,EPHB1,NCALD,ETV1,NRN1,RACK1,FCGR1A,ANKFY1,COQ5,SMC2,UFM1,GAD1,DISC1,SRCAP,SULT1C4,PPARGC1A,HPGDS,RAB30,MSL3,STMN2,RNFT2,UBE2QL1,MIER3,VSIG4,HMGCL,AGBL5,ZDHHC15,USP51,NEGR1,SOWAHA,IL6ST,NME9,ITPKB,KIF5A,CYP27C1,SYTL4,NCOA7,LSS,SMAD1,SMAD9,PIK3AP1,MAP4,MBNL1,MEIS1,DBNL,MSR1,ZNF862,MYT1,PCDH9,PCSK5,GNG2,NLGN3,NALCN,CCSER2,MTRF1L,EPB41L4B,PPM1B,PPP1R1A,PPP3CA,GRAMD1C,CNTLN,TMEM260,PTPRG,PTX3,RASGRF2,RGS4,RIC8B,ADAL,ABCA11P,ZNF331,RMI1,SCN7A,SCN8A,CNKSR2,LIMCH1,KDM4C,POGZ,SS18,ERBIN,SEPT8,RGL1,SYP,SYPL1,TACR1,FAM208A,SYNE1,RNF216P1,AP4E1,TIAM1,CSMD1,TNS1,SYNPO2,DCBLD1,PLEKHH2,TOM1L2,VSNL1,ZNF70,ZNF74,ZNF142,ZNF154,TMEM237,ZSCAN26,ZFAND5,CIAPIN1,PPP1R3F,ITM2C,WNK3,RGS7BP,FAM13C,ADAMTSL3,MSRB3,SRGAP2B" MicroRNA hsa-miR-1278:mirSVR_highEffct hsa-miR-1278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.12E-57 4.54E-53 3.81E-56 3.51E-55 145 820 "KCNH8,ACADM,BEND6,KLHL13,TXNDC16,CC2D2A,TAOK1,PHF12,TNRC6C,IGDCC4,ARRB1,CADPS,ZBTB10,EIF4G3,DPY19L3,ATP6V0A1,DST,SCAPER,PTBP2,RUNX1T1,CCNH,NDST3,RAB28,MYL6B,QKI,ARHGEF6,COL4A5,LETMD1,RCHY1,RNF14,CS,OSBPL3,SIPA1L1,CCDC144A,DOCK4,TBC1D5,LIN54,PITPNC1,ZNF804A,MYEF2,TIAM2,ZC3H11A,CHRDL1,DLX1,DTNA,DNM1L,EDIL3,RASGRP1,KLHL5,YAF2,APH1A,PLEKHA1,TMEM35A,EYA1,GMPR2,ABCA8,ACSL4,KAT8,POLR1B,FGF13,POLK,IP6K2,PSD2,SMC2,UFM1,TPK1,KHDRBS3,KIAA1841,TUBGCP4,MSTN,PPARGC1A,RNPS1,TNRC6A,ADGRA3,GRIA2,CELF5,RBPJ,IL6ST,KIT,IPO5,LAMP2,LIMS1,ZNF667-AS1,MATN2,MEIS1,ZNF92,NEFM,PDE4B,OLA1,NALCN,PIK3C2A,PURG,SCHIP1,PRKACB,CEP41,RELN,CNTLN,PTK2,PTPN13,TTC13,PPP2R3C,OXR1,ERI2,UBR7,ZNF532,DCUN1D2,EXD2,ALG9,ROBO1,RPE,LRRK2,RTN1,SEMA6D,SUPT20H,ARX,FNDC3A,SEPHS1,CCDC88A,SLC12A2,MYO16,TRERF1,SP4,KDM4C,MCF2L2,CLASP2,NKAIN2,ERBIN,STAU1,KANK1,NECAB1,PRRC2C,ADGRL3,TCF12,AKTIP,UCHL1,CCDC14,CLDND1,ZNF711,ZNF17,ZNF45,ANKS1B,EMSY,MPPE1,PDSS2,GAN" MicroRNA hsa-miR-892b:mirSVR_highEffct hsa-miR-892b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.65E-57 4.84E-53 4.05E-56 3.73E-55 147 843 "ACADM,ACHE,PWWP2A,KIAA1211,PCDH10,UNC79,FAM135A,AMPH,DPP10,APC,UPRT,PPFIA3,PLA2G4C,PCDHGB4,ATP1B3,TTLL9,GPR146,MTMR2,AP4M1,SRSF11,PLAA,PPT2,CNN3,SLC4A8,SMARCAL1,AKAP12,NCOR1,VAC14-AS1,DZIP3,ERC2,RIMS2,ZSCAN23,LONRF1,MAML1,MFAP3L,RHOBTB1,DNAH9,MAMLD1,DNAJB6,E2F5,OPTN,IRAK4,FGF12,HPCAL4,VTI1B,ANKFY1,SPECC1,CELF1,FYB1,IGSF5,PPARGC1A,RNPS1,ZNF638,CBX1,LNX1,PCLO,GRIA2,PRDM5,ZBTB49,MAP4K5,MUM1,ZHX1,HMGCR,SMAP1,ZNF181,ZNF678,CREG2,SYTL4,NCOA7,GPR155,MAP4,NCAM2,TBC1D25,PCDHGC3,PRTG,PIK3R1,ZFYVE21,EPB41L4B,PCDHB17P,PRKACB,MAPK10,ELOVL2,PPP2R3C,RGS3,EXD2,ROBO1,RPE,ATP8B4,CLIP1,SCP2,ZFP30,CNKSR2,PPP4R3A,SLC12A4,MBD5,UHRF1BP1L,TEX2,CDK19,TSPYL2,TROVE2,SS18,STAU1,TTBK2,VPS13A,SYT1,MTCL1,TAF6,EXOC7,ZEB1,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,C18orf54,SLC44A1,TSC1,CLHC1,CLDND1,MICU3,MKRN3,EML6,ZNF189,INTS3,SLC30A4,CADM2,FZD3,KAT6A,PHTF2,JMJD1C,RNF146" MicroRNA hsa-miR-2355:mirSVR_highEffct hsa-miR-2355:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-56 5.87E-53 4.91E-56 4.52E-55 139 755 "CLK4,GALNT16,PWWP2A,ZNF608,OSBPL1A,ALCAM,FAM135A,LRFN1,ZFAT,MYH7B,BCAS1,TMEFF1,CHRD,ADAM23,BACH1,ZNF599,GPC2,CA12,PTBP2,CAST,P2RX6,ZBED1,LARGE1,MAGI1,CDO1,RCBTB2,SRSF11,CHN2,SLC4A8,ABI3BP,RNF14,CSNK1G3,PDE4DIP,CCDC144A,TMEM170A,AIF1L,ZNF804A,TIAM2,KIAA0319,ALKBH8,PARD6A,KIF19,DTNA,EDN1,ANKRD46,PHF20L1,MBNL2,EYA1,GMPR2,F5,DLC1,PPP1R1B,FGF11,BAIAP2,RGPD5,NBEA,PDLIM5,STAU2,GABRB3,COPS8,POLL,WDFY3-AS2,ATP2B1-AS1,FAM107A,ATXN2L,TNFAIP8L3,SYNPO,AGFG1,SHISA6,ZNF181,IL6ST,METTL21A,KCNB1,ZFYVE27,MBD1,POC1B,ADAM22,MYO9A,NBL1,NDP,NPTX2,NTRK3,PDCD2,PDE4D,PDE1B,RETREG2,MAPK9,GRAMD1C,LAMA1,RAD51D,RET,FIGN,RNASEL,ELP2,ABCA11P,ZNF354C,COPZ1,ASAP3,WDR37,PPP4R3A,BTBD3,KANSL3,BTBD7,ATF7IP,EPC1,RCOR3,LIMCH1,KDM4C,DBNDD2,POGZ,ZNF302,TTBK2,STAC2,RHBDL3,TACC1,SATB2,FRYL,FAM200B,SIRT1,MTMR14,ERCC6L2,TMPO,TPM1,METTL3,TRIO,TRPS1,RPL7L1,UBE3A,UGT8,RICTOR,ZNF138,SPIRE1,EMSY,PRTFDC1,CIAPIN1,URM1,SLC17A7,ITM2C,MSRB3" MicroRNA hsa-miR-4291:mirSVR_highEffct hsa-miR-4291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-56 6.52E-53 5.45E-56 5.02E-55 158 973 "ABCF1,KCNH8,ABR,CLK4,NCKAP5,NDRG3,PWWP2A,TAOK1,OGT,UPRT,TNRC6C,SLC4A4,ATP2A2,DOCK11,CFLAR,ST3GAL5,IL33,CACNA1A,CALM1,CBS,MTMR7,EVI5L,LOC730101,SRSF11,NRXN3,PLAA,C4orf33,ARMC8,ZNF385A,FAM171B,AKAP12,LRRC3B,CSNK1G3,VCAN,RUBCN,DOCK4,RIPOR2,MATR3,SPOCK2,ARMCX4,GSDME,RHOBTB1,WDR20,DNM1,USP3,DPP6,GOLT1B,SEMA3D,FRY,APH1A,SRRM1,MRPL10,EYA1,F8,STRADA,FER,GTF2IRD2,PRKAG2,RGPD5,TMEM107,SPECC1,TRIM16,CELF1,AP4B1,TUBA8,SULT1C4,GPR162,PCDH17,GGT7,PPARGC1A,LYVE1,GLUL,ZNF638,KCNMB4,GPD1,CCDC184,GRIA2,FAM19A2,PSIP1,ARHGAP36,MIER3,VSIG4,GAREM2,KNDC1,IL6R,NME9,MAP4,MBD1,MBNL1,LRP1B,NF1,CNTN3,ABCB1,LRP12,SEPT4,HYDIN,RELN,PTH1R,PTPRD,PTPRG,FAT4,RBBP6,TRIM68,FIGN,RIC8B,LGI2,CCDC82,ATAT1,KCNIP1,RYR3,NCBP3,PRCD,SCP2,TRA2B,KIF21A,CHD9,NLGN1,SEC31A,EPN2,DHX30,SLC12A2,CPEB4,SNCA,MBD5,SNRPN,RBM34,CLASP2,ELOVL4,SYT1,ANKRD28,MMS19,MTCL1,MCF2L,KIAA1107,DMXL2,SLC19A3,TIAM1,ERCC6L2,TMPO,RIMBP2,KCNE5,TSC1,CLHC1,UCHL1,UGT8,PLEKHH2,P2RY12,WNT7A,PCDH20,ZNF24,SMARCAD1,DHX33,PRDM10,TRIM16L,CASC15,TIGD6,NETO1,FAM198A" MicroRNA hsa-miR-218-2*:mirSVR_highEffct hsa-miR-218-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-56 7.86E-53 6.57E-56 6.05E-55 143 801 "KCNH8,NDRG3,ADCY6,KLHL13,RTL9,AMPD2,LRCH2,SUGT1P4-STRA6LP-CCDC180,PKP4,DPY19L3,BACH1,DST,PTBP2,CAST,CERS5,CHGB,CHN2,NRXN3,MAP4K4,ARMC8,COL4A5,ZFP28,CREM,NCOR1,GDA,SNCAIP,LRRC3B,VCAN,APPL1,MATR3,DGKB,ARMCX2,KIAA0753,ZC3H11A,POM121,DNAH9,FAM78B,DNM1L,EDIL3,APH1A,KMT5B,MRNIP,RCAN2,RABEPK,ARMCX1,ACSL4,ST3GAL6,CEP78,GTF2IRD2,FGF1,FGF11,FGF12,MEX3B,ATP6V1H,ZNF605,FYB1,ZNF559,DCLK2,GPD2,HSF2,EID2B,IL6ST,ZNF678,SLC35G1,KCND2,KIF2A,IPO5,HECTD2,PIK3AP1,MEIS2,SCAMP5,TCEAL5,P2RY13,NCF2,NF1,IGSF11,OGG1,GNG2,OLA1,ZNF655,KCTD15,EXOSC10,DRAM2,GRAMD1C,HYDIN,DCHS2,CNTLN,ANKHD1,PTK2,TMEM260,TTC13,SUSD4,RDX,RNASEL,SETD5,RORB,NEK11,TCP11L1,ZNF354C,SAFB,GALNT10,SH3BGR,SHC4,SEC31A,MTERF2,ELMO2,ANKRD36,KIF13A,DOP1A,MYCBP2,ZC4H2,MPRIP,STAU1,KANK1,PRRC2C,SYPL1,C12orf76,ZEB1,RPGRIP1L,SYNE1,SLC19A3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RGMB,CA14,TTC3,FLRT2,ZNF709,ZFP37,ZNF138,FSTL5,DHX33,PRDM10,HPS4,PDSS2,RNF170,IFT88" MicroRNA hsa-miR-26a-5p:TargetScan hsa-miR-26a-5p TargetScan 1.45E-56 8.12E-53 6.77E-56 6.24E-55 138 746 "PLEKHH1,PWWP2A,PTCHD1,INTS2,KCTD16,ANK2,EP400,APC,CDK13,CCAR2,INSYN2B,DOCK11,ADAM23,BID,GPR146,DST,FUBP1,CACNA2D1,CACNB4,CAMK2A,CD38,CDH2,DCLK1,CNR1,AKAP7,COL9A1,NRG2,HAPLN1,FAM169A,ERC2,PLCXD3,CTH,GREB1,GPSM1,PYGO1,DOCK4,MATR3,DAPK1,PITPNC1,ARMCX2,JAKMIP2,MFAP3L,C2CD2L,SACS,DMD,CPEB2,PHF20L1,EIF4G2,EIF5,RGS17,PAN3,ERBB4,MED12L,PRKAG2,MEX3B,FAM49B,CELF1,FUT9,MPP6,RAPGEF6,MSTN,GPR12,GRB10,DIDO1,LINGO1,HAS2,MIER3,IGF1,CDH20,KCNN3,KPNA5,LIFR,LIMS1,MAP2,MARK1,MAT2A,CHIC1,MEF2C,MITF,MMP16,BLOC1S2,MXI1,MYO9A,NCAM2,NOVA1,P2RY1,PDE4B,PDE4D,PFKFB2,PFKFB3,FAM98B,PIK3C2A,CCSER2,GPSM2,PLCL1,PCDH18,FA2H,PPP2R2B,CEP41,GRAMD1C,PTPN13,PTPRD,MARCH1,ENOX1,FIGN,RFX3,RGS4,NUDT11,RPS6KA2,RTN1,SALL1,ATXN7,FNIP1,GALNT10,MRAS,HSPA4L,CPEB3,FBXO11,NLGN1,FAM214B,BTBD7,CPEB4,EPC1,ARHGAP26,CLASP2,LARP4,MPRIP,PLCB1,FAM208A,GPR161,NACC2,DCBLD1,ANKS1B,PHTF2,RSPRY1,NHSL1,NETO1,GAN" MicroRNA hsa-miR-26b-5p:TargetScan hsa-miR-26b-5p TargetScan 1.45E-56 8.12E-53 6.77E-56 6.24E-55 138 746 "PLEKHH1,PWWP2A,PTCHD1,INTS2,KCTD16,ANK2,EP400,APC,CDK13,CCAR2,INSYN2B,DOCK11,ADAM23,BID,GPR146,DST,FUBP1,CACNA2D1,CACNB4,CAMK2A,CD38,CDH2,DCLK1,CNR1,AKAP7,COL9A1,NRG2,HAPLN1,FAM169A,ERC2,PLCXD3,CTH,GREB1,GPSM1,PYGO1,DOCK4,MATR3,DAPK1,PITPNC1,ARMCX2,JAKMIP2,MFAP3L,C2CD2L,SACS,DMD,CPEB2,PHF20L1,EIF4G2,EIF5,RGS17,PAN3,ERBB4,MED12L,PRKAG2,MEX3B,FAM49B,CELF1,FUT9,MPP6,RAPGEF6,MSTN,GPR12,GRB10,DIDO1,LINGO1,HAS2,MIER3,IGF1,CDH20,KCNN3,KPNA5,LIFR,LIMS1,MAP2,MARK1,MAT2A,CHIC1,MEF2C,MITF,MMP16,BLOC1S2,MXI1,MYO9A,NCAM2,NOVA1,P2RY1,PDE4B,PDE4D,PFKFB2,PFKFB3,FAM98B,PIK3C2A,CCSER2,GPSM2,PLCL1,PCDH18,FA2H,PPP2R2B,CEP41,GRAMD1C,PTPN13,PTPRD,MARCH1,ENOX1,FIGN,RFX3,RGS4,NUDT11,RPS6KA2,RTN1,SALL1,ATXN7,FNIP1,GALNT10,MRAS,HSPA4L,CPEB3,FBXO11,NLGN1,FAM214B,BTBD7,CPEB4,EPC1,ARHGAP26,CLASP2,LARP4,MPRIP,PLCB1,FAM208A,GPR161,NACC2,DCBLD1,ANKS1B,PHTF2,RSPRY1,NHSL1,NETO1,GAN" MicroRNA hsa-miR-542-3p:mirSVR_highEffct hsa-miR-542-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.48E-56 8.29E-53 6.91E-56 6.36E-55 152 904 "RALGAPA1,SYS1,KLHL32,KIAA1211,HECW2,WDR35,TAOK1,ALCAM,LCORL,PHF12,LINC00173,MARCH3,ATP1B3,ATP6V1G2,NRP2,ZNF599,PROM1,SCAPER,IL33,DDR1,THSD7A,COPB2,CHGB,CNOT8,FBXO7,ABCG2,HECTD1,AKAP6,SUMF2,TBPL1,ZFP28,ANKRD44,CLIP3,CSNK1G3,RASGEF1C,CYBB,BRINP1,DBI,GSDME,PLPPR4,SV2B,WDR20,DMD,DTNA,DNM1L,ANKRD46,EBI3,EGFR,PAN3,ERCC2,TLR7,MRVI1,F8,FCGR1A,FGF12,FGF13,SUCO,C2orf88,POMT1,UFM1,CELF1,SARAF,GALC,TUBGCP4,GLI2,MAP7D2,STMN2,KAT7,HNMT,ZDHHC15,MARK1,MID1,ZNF680,ZNF92,P2RY13,NOVA1,DNHD1,NTRK3,NUCB2,OCRL,PFKFB3,XRN1,MTRF1L,MAPKAP1,STRN3,MAGEL2,PPM1B,PPP2R2C,EPDR1,MAPK9,GDPD2,ZSCAN32,ZNF615,PPP2R3C,REV3L,FIGN,RGS3,EXD2,ROBO1,RORB,ELP2,ATP8B4,TRAPPC13,ATXN7,PRCD,COPZ1,FNDC3A,FHOD3,R3HDM2,CNKSR2,SYBU,NUBPL,SLC8A1,SLC12A2,ZFP1,ZSCAN29,KLHL7,ANKRD28,MCF2L,SATB2,CUX2,RPGRIP1L,TCF12,SYNE1,DOCK9,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,TLR4,TPM1,NPL,METTL3,TRIO,TSC1,TUBB1,PCDH20,ZBTB14,ZNF189,ZNF225,EMSY,MFF,ADAMTS9,PDSS2,PHTF2,JMJD1C,RNF170" MicroRNA hsa-miR-609:mirSVR_lowEffct hsa-miR-609:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-56 9.82E-53 8.18E-56 7.53E-55 162 1024 "RALGAPA1,KCNH8,ABR,EMILIN3,SYS1,PSMG3-AS1,KIAA1211,LRFN2,KIAA1324,CC2D2A,USP35,PITPNM2,DDO,TMEM108,TTLL9,ADGRB1,BMP7,CAST,ARHGEF2,NUMBL,NRXN3,IQCK,IGDCC3,TRIM69,RASGEF1C,SLITRK5,KIAA0040,HDAC9,MYADM,LONRF1,DAPK1,SPOCK2,LYPD1,RHOBTB1,SNAP91,SV2B,RAB39B,DNM1,CPEB2,DTNA,MAMLD1,DNAJB6,E2F5,EDN3,FCF1,TMTC1,FAM13A,PHF20L1,EGFR,STARD3NL,VPS13B,EPB41L2,STX2,SPEG,HSPA12B,ACSL4,STRADA,TMEM164,AMOTL2,EVL,POMT1,TMEM107,ST6GALNAC3,DLL3,SDCBP2,GABBR1,C15orf41,DISC1,CPLX1,IGSF5,TTBK1,STARD3,TPPP,GRIA2,BTN2A1,FAM69A,KCNK3,KCNN2,ASPRV1,MAP4,LYPLAL1,MBP,ADAM11,MEF2C,MMP16,MN1,MYO6,NME4,CNOT4,NTRK3,PDE3A,RETREG1,GPSM2,SLC25A23,ING3,SH3KBP1,DRAM2,PPP2R2B,PRKCB,MASP1,DEF8,QRICH1,PIGG,PTCH1,PTPRD,FAM66C,KHDRBS2,ERI2,UBR7,PBRM1,KIRREL1,SGSM1,CLIP1,SEMA6D,SUPT20H,MYO18A,FHOD3,ST6GAL1,ABLIM3,SLC8A1,SLC22A4,SMARCA4,IFT122,SNCA,DOK5,KDM4C,CLASP2,ZC3H4,PRRC2C,ARC,TACR1,TAL1,FBXW11,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,PMS2CL,DICER1,LRRC8A,RASD2,TPM1,DOK6,DCBLD1,TSC1,FAM155A,OSBP2,USP1,NPDC1,ZBTB14,TRIM9,EMSY,EVI5,ADAMTS9,FAM47E,RNF170,SPATA13" MicroRNA hsa-miR-18b:mirSVR_highEffct hsa-miR-18b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.95E-56 1.09E-52 9.06E-56 8.34E-55 136 726 "KCNH8,AS3MT,TMCC3,PLEKHH1,PWWP2A,BEND6,ALCAM,MAP4K3,VAT1L,NCOA1,ATP1B3,NAE1,CA8,CA12,ZNF501,USP6,SYNGR3,LRBA,LRRFIP1,QKI,TBPL1,AHCTF1,RNF14,CLIP3,RGS6,SIPA1L1,SOCS5,DZIP3,GREB1,PUM1,RIMS2,DCAF4,DOCK4,HDAC9,LIN54,MATR3,DBI,PITPNC1,SNAP91,TMCC2,SEC16A,DTNB,PHF20L1,VPS13B,TLR7,DLC1,CEP78,MED12L,FGF1,FGF12,SUCO,FOLH1,KHDRBS3,STAU2,OGA,SULT1C4,PPARGC1A,STARD3,ARHGAP36,HLF,HNMT,ZNF491,ZDHHC15,HSF2,SOWAHA,MBNL1,OCRL,PCSK1,PDE4D,PDE1B,GPR173,PIK3C2A,ZNF655,SNX10,EXOSC10,SH3KBP1,PRKACB,MAPK4,HYDIN,DIRAS2,MASP1,VPS13C,SNRK,IQSEC3,NWD1,RBBP6,RBBP8,MORC4,FIGN,RNASEL,SATB1,CSRNP3,ZFP30,SLC6A11,SMARCC2,MBD5,DOP1A,PDZD2,KDM3A,KDM4C,TEX2,CDK19,TSPYL2,SPART,ATP10B,NKAIN2,NXT2,CEP68,VPS13A,TMEM150C,ANKRD28,C12orf76,ZFP90,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,TEK,NPL,PLEKHH2,VSNL1,WIPF1,ZBTB14,TRIM9,CELF4,EMSY,CADM2,ADAMTS9,ITM2C,EPM2A,MSRB3" MicroRNA hsa-miR-143*:mirSVR_highEffct hsa-miR-143*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.54E-56 1.42E-52 1.18E-55 1.09E-54 134 706 "DPY19L2P4,KLHL13,SMIM17,MARCH4,OGT,APC,BCAS1,SEMA4G,CASK,CADPS,NCOA1,ST3GAL5,LDB2,MTMR7,ARHGEF2,TPP1,FBXO7,ABCG2,QKI,FHL5,ABI3BP,RCHY1,FAM171B,ANKRD44,NCOR1,SLITRK5,GAPVD1,ARHGAP24,ZNF337,ARMCX4,PLPPR4,SACS,DTNB,EGFR,PLXNC1,PLEKHA1,MTSS1L,EYA1,NRN1,PRMT5,FGF1,SCARA3,C2orf88,CELF1,MSANTD4,OGA,GAD1,KDM2B,PLCD4,MAP4K5,ZHX1,FRMD3,MIER3,SMAP1,RBPJ,ZNF678,NME9,SLC35G1,KCNN2,STMN1,MAT2A,MATN2,TM6SF1,LRP1B,NELL2,DNHD1,PCSK5,NLGN3,PIK3C2A,FAM216A,PURG,TRHDE,SCHIP1,MINDY2,MAPK9,GRAMD1C,VPS13C,GDPD2,CNTLN,TMEM260,FAM184A,ZNF493,RBBP6,REV3L,ZFHX4,C12orf49,KLHDC8A,RORB,MRAP2,LRRK2,RYR3,DGLUCY,SATB1,SHC4,FAM81A,KANSL3,CCDC88A,BTBD7,RCOR3,SNCA,DOP1A,KDM3A,SP2,ZSWIM8,KDM4C,CLASP2,POGZ,LARP4,CAMTA1,ATMIN,ZFPM2,THRA,ERCC6L2,TRIO,KCNE5,FAM155A,LMF1,P2RY12,PCDH20,ZBTB14,ZNF19,TRIM9,ZNF45,ZNF138,LAMP5,SMARCAD1,MAP3K12,EMSY,SLC38A1,WNK3,KAT6A,ADAMTSL3,NETO2,JPH3" MicroRNA hsa-miR-6835-3p:TargetScan hsa-miR-6835-3p TargetScan 4.26E-56 2.38E-52 1.98E-55 1.82E-54 131 677 "ELFN2,PWWP2A,PTCHD1,HECW2,ARHGAP20,GPRASP2,OGT,CDC42BPA,C6orf89,APC,CDK13,MARCH3,N4BP2L1,NRP2,FUBP1,MTMR3,JAZF1,LDLRAD4,CAMK2A,RUNX1T1,CBFA2T2,CD38,C1orf52,L3MBTL4,CFL2,CLTC,QKI,IGLON5,ARHGEF6,CNTN1,ARMC8,CCDC144A,DOCK4,DCAF8,MATR3,ELMSAN1,JAKMIP2,MFAP3L,MTX3,FAM107B,EXOG,RAB39B,DMD,CDON,CPEB2,DRP2,RCAN1,EDNRB,PHC2,PLXNC1,RCAN2,RAB9B,DLC1,PPP1R1B,MED12L,FHL1,FOXO3,FLT1,PDLIM5,CELF1,FYN,GABRB3,GATM,PCDH17,PPARGC1A,CBX1,MAP7D2,GNAO1,GPR37,HAS2,IL6ST,KLHL23,KCNN3,LAMP2,LIFR,LIMS1,SAMD5,GPR137C,CNTN3,PDE1C,PDE3A,PDE1B,PDPK1,GNG2,PIK3R1,POLG,PRKAB2,CEP41,CNNM2,ANKHD1,PTPRD,NKAIN1,CEP97,RDX,REV3L,GTDC1,FIGN,KLHL11,NUDT11,LGI2,AP1AR,SATB1,ATXN7,SCN7A,PPM1E,CPEB3,FNDC3A,HECW1,ERC1,NKAIN2,KLHL7,PRRC2C,PLCB1,ANKRD28,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ASXL3,OSBP2,BCL2L13,DPYSL5,FZD3,NETO1,GAN" MicroRNA hsa-miR-1279:mirSVR_highEffct hsa-miR-1279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.37E-56 2.45E-52 2.03E-55 1.87E-54 150 888 "ABHD6,KLHL32,BEND6,INTS2,HECW2,HFM1,ZFAT,MAP4K3,TMEFF1,DPY19L3,ATP6V0A1,BCHE,DST,KALRN,LDB2,CCNH,LRBA,MAGI1,TIGD7,MS4A7,CNTN1,FAM149A,ABI3BP,RTTN,CLOCK,SLITRK5,PHF14,RIMS2,ARHGAP24,DAPK1,HEPH,DDX46,SACS,SV2B,CPEB2,SLC12A6,RCAN1,GOLT1B,HIPK3,MBNL2,EGR3,RGS17,EMX2,EPHB1,ACSL4,DLC1,KAT8,FGFR1,SUCO,IQCG,ANKFY1,NOP56,SMC2,PDLIM5,STAMBP,STAU2,ZMAT1,MEGF10,GABRB3,GABRG2,SULT1C4,GPR162,TOX3,FERMT2,CCDC184,ATOH8,ZHX1,MIER3,HSF2,SHISA6,RBPJ,SCIN,KIT,LIG4,HECTD2,MBD1,MBNL1,KCTD6,MGAT3,MIA2,NCAM2,NEFM,NEK1,NRCAM,NTRK3,NUCB2,CLDN11,OXTR,GPR137C,CNTN3,PCDH9,SNX10,GPSM2,PLCL1,SCHIP1,EPB41L4B,PRKACB,MAPK9,PTCH1,PTK2,ACSM5,TMEM255A,RDX,GTDC1,RGS12,CARF,GSTCD,CCDC25,ATP8B4,LRRK2,ZNF354C,ZFP2,NLGN1,WDR37,CPEB4,KDM4C,ZC3H13,SSTR2,SEPT8,DIP2A,SEPT3,NUDT10,PLCB1,SYT1,ADGRL3,RPGRIP1L,TCF12,PCDHGB7,DOCK9,PCDHB6,ZFPM2,AKTIP,FAM124A,PIK3R5,TPM1,METTL3,OSBP2,ZNF711,KCNT2,ZNF45,LYPD6,ZNF177,FSTL5,EML6,EMSY,SLC17A7,CASC15,JMJD1C,RNF170,FXR1" MicroRNA hsa-miR-198:mirSVR_highEffct hsa-miR-198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.62E-56 2.59E-52 2.14E-55 1.97E-54 145 831 "FAM135A,AMPD2,OGT,LCORL,CDK13,ATP1A3,ALDH7A1,ADAM15,BACH1,ADGRB3,CASTOR3,JAZF1,C5,GPC2,CAST,SPAG9,NFS1,CBS,LDB2,ENTPD6,L3MBTL4,QKI,TMEM184B,FAM149A,LETMD1,CNRIP1,CPS1,SH2B1,SNCAIP,CSF2RA,ARHGEF10,OSBPL3,CSNK1G3,PDE4DIP,CST3,SLITRK5,TMEM170A,DDX46,DPH1,APH1A,MBNL2,TUBD1,RCAN2,ANKMY1,FCGR1B,SEC24B,FER,FGF11,FGF14,TMEM164,ATP5PD,AGAP3,EFCAB2,APOPT1,ZNF605,CELF1,STAU2,AP4B1,MEGF10,CHL1,TRAF3IP2,ERAP1,KIAA1841,KDM2B,LOXL3,LILRA2,GRIA2,DIDO1,FRMD5,VSIG4,AGBL5,ZDHHC15,LRRC75A,JAK2,GPR62,SYTL4,SMAD1,MAP4,MARK1,POC1B,MSR1,MYO9A,NDP,NNAT,CNOT4,CDK18,GNG2,ABCB1,FAM218A,RETREG1,GPSM2,JAKMIP1,SCHIP1,LRRN3,GRAMD1C,HYDIN,VPS13C,CNTLN,PTPRE,ZMAT4,FIGN,RGS12,NUDT11,RNASEL,ZFHX4,EXD2,ATP8B4,ABCA11P,RYR3,MAPK12,SH3GL3,FERMT1,CHD9,FBXO11,PPP4R3A,SLC11A1,SNRPN,CDK19,NKAIN2,CEP68,STXBP1,TMEM150C,ASTN2,C12orf76,FAM208A,FBXW11,TCEA1,CLASP1,SZT2,SYNE1,NAT16,PUM2,HIF3A,FAM155A,UGT8,BCL2L13,VLDLR,NDRG4,SLC30A4,ZXDA,STOX2,ADAMTS9,GAL3ST3,SLC17A7,KCNAB1" MicroRNA hsa-miR-34c-5p:mirSVR_highEffct hsa-miR-34c-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.62E-56 2.59E-52 2.14E-55 1.97E-54 151 900 "SYS1,KDM5D,ADD2,ADRA1D,MTUS1,HACE1,KIAA1324,ALCAM,DOC2A,ANK2,PKP4,VAT1L,TNRC6C,TMEFF1,NCOA1,DPY19L3,ADAM23,BCS1L,SYNJ2,ARHGEF7,JAZF1,WASF1,CALB1,KALRN,DGKI,ZMYM4,EVI5L,TIGD7,NUMBL,EPS15L1,RAB33A,SULT4A1,HECTD1,AKAP6,MYRIP,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,ERC2,PNPLA8,ZSCAN23,ZFYVE16,IST1,DGKB,BRINP1,GIT2,ELMSAN1,RHOBTB1,RCAN1,DNM1L,E2F5,FAM13A,KMT5B,RGS17,TMEM35A,C8orf37,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,PSD2,SLC37A3,NOP56,GABRA3,GHDC,MTHFD2,C15orf41,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,CCDC184,PCLO,NXPH3,ARHGAP36,ITPKB,KCND1,KCND2,KCNK3,KIF5A,KIT,HECTD2,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,NTRK3,CDK18,GPR85,CCSER2,JAKMIP1,PURG,STRN3,ING3,PKIA,CNTLN,MTMR10,PTPRD,EML5,PTX3,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,RIC8B,RNASEL,ZFHX4,SPIN3,TCP11L1,SATB1,ATXN7,KDM4D,DMRTC1,KIF13A,SNRPN,PDZRN3,POGZ,ARHGEF9,SYT1,CAMTA1,FAM208A,ATMIN,SATB2,RPGRIP1L,DOCK9,USP32P1,FRYL,RNF216P1,ITGB3BP,TRIO,TSN,TUBB1,PLEKHH2,BCL2L13,DHX33,MDH1B,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-383:mirSVR_highEffct hsa-miR-383:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.63E-56 3.15E-52 2.61E-55 2.40E-54 164 1057 "AS3MT,GALNT13,PWWP2A,MTUS1,KCTD16,KIAA1324,CC2D2A,FAM135A,AMPD3,PARG,ZBTB10,NUMB,BARD1,SEC11C,CBLN1,ZNF501,ZMYM4,LARGE1,RCBTB2,MS4A7,AKAP7,AKAP6,RBM39,AKAP12,PHACTR3,CNTNAP2,PHF14,GREB1,RIMS2,PPP6R2,HDAC9,PABPC5,ELMSAN1,MYEF2,FBXL5,SV2B,DMTF1,DTNA,EBF1,EDN1,EDNRA,YAF2,EGFR,TENM1,ELN,CALCRL,PAN3,ENO2,VPS13B,GPHN,RPS6KC1,TAOK3,FGF13,POLK,MEX3B,SEMA4D,CSPG5,STAU2,SARAF,ABLIM2,OGA,FAM120B,DISC1,PCDH17,RAB30,TOX3,GNAO1,GPD2,PRUNE2,RNF165,FAM222A,UBE2QL1,VSIG4,NKD1,ZIC5,IL12A,CREG2,IPO5,LIMS1,ZNF667-AS1,MARK3,MEST,POC1B,AFDN,ZNF680,NELL2,NNAT,CNOT4,NOVA1,DNHD1,NUCB2,CLDN11,CNTN3,CDK18,SLC10A4,FAM218A,RETREG1,SMOX,MAPKAP1,STRN3,EPB41L4B,SH3KBP1,PPM1B,TMEM260,ZSCAN2,SUSD4,RDX,UBR7,RNASEL,CARF,RPE,SNX22,TCP11L1,SALL1,LRFN5,SHMT2,AMBRA1,FNDC3A,FAM81A,SLC9A5,CMTR2,SP4,KDM4C,PEG10,RBM26,SPART,CLASP2,CLSTN2,RGL1,KLHL7,ANKRD28,ADGRL3,AGTPBP1,KLHL4,TPCN2,SYNE1,FRYL,SIK3,CYB561A3,SIRT1,ITGB3BP,PRRT1,WBP2,STXBP4,PPIL6,ANKRD20A2,FAM155A,WNT7A,XRCC4,TRIM9,ZFP41,TCEAL7,ZXDA,EMSY,PRDM10,TUBA1A,ADAMTS9,SLC17A7,KCNAB1,EPM2A,RGS7BP,FZD3,RNF146,FAM198A" MicroRNA hsa-miR-1274a:mirSVR_lowEffct hsa-miR-1274a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.64E-56 3.15E-52 2.61E-55 2.40E-54 188 1364 "KDM5D,ADCY6,ADD1,PLEKHH1,ADORA2A,KIAA1211,AK2,ZNF578,OGT,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,PHYHD1,PPFIA3,USP37,IGDCC4,DYNLL1,DST,SGCE,IL33,CACNA1B,CABP7,KALRN,CERS5,MTMR7,ARHGEF2,LARGE1,SOCS6,ASIC3,NRXN3,TPP1,CNGA3,SUMF2,AKAP5,NCOR2,GDA,AATK,SNCAIP,CSF1R,ARHGEF10,ARHGAP32,EARS2,AIF1L,SV2B,EXOG,DOCK2,DMTF1,ACOT8,FARSB,ABCC5,SNX29,ANKRD46,CNNM1,SEMA3D,TMTC1,YAF2,CERCAM,ELN,TMEM35A,EMX2,MRPL10,ADGRV1,REEP2,CLVS1,CHST15,PPP1R1B,FER,FGF1,IP6K2,EFCAB2,POMT1,UFM1,PDLIM5,RASL10A,CELF1,STAU2,DOT1L,ERAP1,DISC1,GFER,PCDH17,POLL,GPD2,STON1,LPAR4,PLCD4,CLASRP,FAM19A2,RABL2A,ADAMTS6,SLC2A6,DDX19B,SYNPO,HNF4G,CPT1C,LRRC75A,C2orf72,SLC6A17,SLC35G1,KCNK3,CYP27C1,MAN2A2,CHIC1,XRRA1,LYRM9,ALDH1L2,NNAT,CNOT4,OCRL,ZNF713,CDK18,ZNF655,ZFYVE21,PLCB2,POLR2F,EPDR1,GRAMD1C,HYDIN,CNNM2,VPS13C,CYBC1,CNTLN,PTCH1,PTPRB,PTPRD,PTPRE,RAD51D,SH3TC2,RGS12,MRPS18A,MRAP2,ZC3H14,ZNF568,ATXN2,ZNF821,COPZ1,AMBRA1,ANKRD6,ABLIM3,PPP4R3A,KANSL3,SLC11A1,ATF7IP,CPEB4,IFT122,KIF13A,ZSWIM8,NMNAT2,ERC1,SPTB,ZBTB43,TSPYL2,CAMTA2,ERBIN,ELOVL4,SEPT8,CEP68,PHLDB1,KANK1,STXBP1,PRRC2C,SYNE2,ARHGEF9,VPS13A,MCF2L,EXOC7,IQCE,TBL1X,RPGRIP1L,FRYL,SIK3,GPR161,METTL3,SMUG1,STXBP4,UBE3A,CFAP298,ZBTB14,ZNF154,TMEM237,FSTL5,UPF3A,EMSY,GDPD5,LINC02210,UBE3B,FAM219B,RNF170" MicroRNA hsa-miR-892a:mirSVR_highEffct hsa-miR-892a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.32E-56 4.65E-52 3.85E-55 3.54E-54 156 963 "RALGAPA1,XKR4,NDRG3,PTCHD1,HECW2,PKP4,TMEM108,SLC4A4,ADGRB3,BARD1,ARHGEF7,KALRN,HIP1R,RHBDL1,ARHGEF25,ZNF501,P2RX6,SEPT7,EVI5L,TIGD7,CLGN,QKI,SRP14-AS1,CLOCK,C2CD2,RBM39,HAPLN1,ARHGEF10,VCAN,SLITRK5,PHF14,HDAC9,LONRF1,LYPD1,DDX46,USP3,DYNC1I1,DMTF1,EDNRB,FCF1,KMT5B,GOLGA7,ING4,NRN1,MEX3B,SLC37A3,NOP56,GALNT15,MSTN,AHDC1,GLI2,TNRC6A,ZNF638,GPT2,FUT10,ATP2B1-AS1,MAP4K5,FRMD5,ACOT7,HMGCR,HNMT,SCIN,IL6ST,IBA57,HECTD2,MBNL1,MKLN1,NF1,VWA2,NPTX1,NTRK2,GLIPR1L2,PCDH8,PDCD2,PDE1C,GPR85,CYTL1,NLGN3,FAM218A,ANKRD16,PSAT1,LRRN3,PRKACB,PKIA,DIRAS2,RELN,EML5,PTPRG,C1orf109,CEP97,TMEM255A,RDX,RET,REV3L,GTDC1,RFX3,RGS3,RGS4,SETD5,NCBP3,TRAPPC13,SATB1,CSRNP3,ATXN2,SUPT20H,SHC4,CHD9,FHOD3,R3HDM2,SLA,PREX2,CCDC88A,TET1,CPEB4,RCOR3,LIMCH1,MYO16,SP4,KANK1,MTCL1,TAF9,TBCEL,KLHL4,ATMIN,TCEA1,ZEB1,TCF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,MTMR14,TMPO,TPM1,CLIP2,XPO1,XRCC4,ZNF711,KCNT2,REEP1,FSTL5,ANKS1B,EMSY,NAV3,WNK3,PLSCR4,FAM13C,KAT6A,ADAMTSL3,CPNE4" MicroRNA hsa-miR-31:mirSVR_highEffct hsa-miR-31:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.48E-56 5.31E-52 4.38E-55 4.03E-54 148 870 "CLK4,NCKAP5,KDM5D,NDRG3,DPY19L2P4,OLMALINC,AGT,RTL9,PHF12,CDK13,NUMB,CCAR2,DPY19L3,JAZF1,WASF1,THSD7A,RUNX1T1,MTMR7,DGKI,ARHGEF2,SRSF11,ASIC3,CLCN3,QKI,AKAP7,IQCK,SLC4A8,PREPL,CSF1,PDE4DIP,CTH,GPSM1,CYBB,HDAC9,ARHGAP32,DCAF8,TM9SF4,PABPC5,ZNF804A,RHOBTB1,DPP6,E2F6,EDNRB,FSD1L,EZH1,ACSL4,FCGR1A,SPSB4,POLK,SPECC1,APOPT1,KHDRBS3,ST6GALNAC3,GABBR1,SULT1C4,GLI2,TOX3,TNRC6A,RABL2A,SOX21,MAP4K5,RASSF8,NXPH3,BACH2,VSIG4,HMGCL,SHISA6,PIK3AP1,ZNF667-AS1,MAP4,MEST,NF1,ALDH1L2,IGSF11,OPRL1,TREM2,CYTL1,PIK3C2A,SNX10,RETREG1,EPB41L4B,SH3KBP1,PRKACB,PRKCB,HYDIN,SAMD9,VPS13C,STK32A,TMEM145,ZNF615,RET,PRRT2,RGS4,ZFHX4,GSTCD,CCDC25,MRAP2,ATAT1,SEMA6D,ATXN2,ZFP30,FERMT1,SHC4,FNDC3A,WDR37,BTBD3,WDR47,SEPHS1,ARHGEF40,CDK5RAP3,KBTBD4,ATF7IP,FAM126B,PDZD2,SP2,PEG10,LMO3,CLASP2,ZNF302,NKAIN2,NXT2,PHLDB1,KANK1,NSFL1C,JMJD6,TAF9,SATB2,TCF12,TEK,DICER1,TLR4,FAM124A,CSMD1,TNS1,IL34,SMUG1,KCNE5,TSN,OSBP2,WIPF1,ZNF19,ZNF540,ZNF74,EMSY,CIAPIN1,PDSS2,FZD3,ST7" MicroRNA hsa-miR-302f:mirSVR_highEffct hsa-miR-302f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-55 6.59E-52 5.44E-55 5.01E-54 162 1038 "FMNL2,BEND6,HECW2,OSBPL1A,ALCAM,LRCH2,LCORL,PKP4,VAT1L,STX16,ATP2B2,LINC00847,SEC11C,DST,ST3GAL5,JAZF1,IL33,THSD7A,PTBP2,CBR1,LRBA,SRSF11,CHN2,B4GALT6,RAB28,PLAA,FHL5,AKAP7,COL4A5,COX4I1,TOGARAM2,SLC35F1,CREM,CRHBP,AKAP12,HAPLN1,PHF14,PNPLA8,CTH,GPRASP1,ARHGAP24,HDAC4,IST1,KIAA0319,USP3,DYNC1I1,NR1D2,DNM1L,EDNRA,SEMA3D,KLHL5,FAM13A,PHF20L1,GOLGA7,TENM1,RGS17,DLC1,CEP78,CHST15,FER,AGAP2,KHDRBS3,STAU2,GABRG2,C15orf41,KIAA1841,GCNT2,AHDC1,RAB30,TOX3,PRUNE2,GPR12,BVES,ADAMTS6,MAP4K5,SHISA6,INPP1,SLC35G1,KIF5A,L1CAM,PAXBP1,NCOA7,PACRG,MARK3,MBD1,MEIS1,MSR1,ZNF92,BEX5,ZC3H12B,NEK1,NF1,OPA1,ETFRF1,PDE4D,ZFYVE21,PLEC,MAPKAP1,RETREG2,PPM1B,PPP2R2B,PRPSAP2,PTN,PTPRG,PID1,CEP97,CCDC40,MSANTD2,RDX,ERI2,NUDT11,CCDC82,CARF,ROBO2,RORB,GLDN,CCDC112,SATB1,ZFP30,SHC4,NLGN1,PREX2,CDK5RAP2,RCOR3,CMTR2,SNRPN,PDZRN3,BDP1,SP2,MYCBP2,SPP1,NEK4,SEPT3,NECAB1,VPS13A,ADGRL3,ATMIN,RNF175,SIK3,ITGB3BP,SLC44A1,RGMB,PPIL6,DCBLD1,CLHC1,UBE2H,GORASP1,CCDC14,P2RY12,CLDND1,GUSBP1,MICU3,KCNT2,MKRN3,SPHK2,REEP1,FSTL5,EVI5,FAM13C,PHTF2,TIGD6,MSRB3" MicroRNA "TGAATGT,MIR-181A:MSigDB" "TGAATGT,MIR-181A:MSigDB" MSigDB 1.55E-55 8.65E-52 7.11E-55 6.55E-54 109 465 "FMNL2,GALNT16,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,ATP2A2,ATP2B2,RNF182,ADGRB3,HCN2,ARHGEF7,JAZF1,CAMK2G,CBFA2T2,LRBA,CACNA2D2,QKI,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,WDR20,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,NCALD,BAIAP2,MEX3B,SYT3,PDLIM5,GGT7,TCERG1,GRB10,GRIA2,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,IPO5,MAPT,MAT2A,ADAM11,AFF1,MSI1,SFR1,NOVA1,IGSF11,PRTG,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,TMCC1,USP33,DOP1A,LMO3,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,ZIC2,TRIM9,SPIRE1" MicroRNA "TGAATGT,MIR-181C:MSigDB" "TGAATGT,MIR-181C:MSigDB" MSigDB 1.55E-55 8.65E-52 7.11E-55 6.55E-54 109 465 "FMNL2,GALNT16,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,ATP2A2,ATP2B2,RNF182,ADGRB3,HCN2,ARHGEF7,JAZF1,CAMK2G,CBFA2T2,LRBA,CACNA2D2,QKI,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,WDR20,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,NCALD,BAIAP2,MEX3B,SYT3,PDLIM5,GGT7,TCERG1,GRB10,GRIA2,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,IPO5,MAPT,MAT2A,ADAM11,AFF1,MSI1,SFR1,NOVA1,IGSF11,PRTG,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,TMCC1,USP33,DOP1A,LMO3,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,ZIC2,TRIM9,SPIRE1" MicroRNA "TGAATGT,MIR-181B:MSigDB" "TGAATGT,MIR-181B:MSigDB" MSigDB 1.55E-55 8.65E-52 7.11E-55 6.55E-54 109 465 "FMNL2,GALNT16,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,ATP2A2,ATP2B2,RNF182,ADGRB3,HCN2,ARHGEF7,JAZF1,CAMK2G,CBFA2T2,LRBA,CACNA2D2,QKI,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,WDR20,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,NCALD,BAIAP2,MEX3B,SYT3,PDLIM5,GGT7,TCERG1,GRB10,GRIA2,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,IPO5,MAPT,MAT2A,ADAM11,AFF1,MSI1,SFR1,NOVA1,IGSF11,PRTG,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,TMCC1,USP33,DOP1A,LMO3,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,ZIC2,TRIM9,SPIRE1" MicroRNA "TGAATGT,MIR-181D:MSigDB" "TGAATGT,MIR-181D:MSigDB" MSigDB 1.55E-55 8.65E-52 7.11E-55 6.55E-54 109 465 "FMNL2,GALNT16,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,ATP2A2,ATP2B2,RNF182,ADGRB3,HCN2,ARHGEF7,JAZF1,CAMK2G,CBFA2T2,LRBA,CACNA2D2,QKI,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,WDR20,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,NCALD,BAIAP2,MEX3B,SYT3,PDLIM5,GGT7,TCERG1,GRB10,GRIA2,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,IPO5,MAPT,MAT2A,ADAM11,AFF1,MSI1,SFR1,NOVA1,IGSF11,PRTG,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,TMCC1,USP33,DOP1A,LMO3,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,ZIC2,TRIM9,SPIRE1" MicroRNA hsa-miR-194*:mirSVR_highEffct hsa-miR-194*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-55 1.02E-51 8.37E-55 7.71E-54 124 612 "PTCHD1,INTS2,HECW2,PITPNM2,AMT,FGD2,UPRT,LGR5,ARRB2,MARCH3,ADGRB2,AP1M1,KALRN,CAST,LDB2,CCNH,USP6,CD86,ARHGEF2,CDO1,TIGD7,NUMBL,CNOT8,TPP1,AKAP5,CPS1,PREPL,RBM39,CRMP1,SNCAIP,SEC24C,DZIP3,ARHGAP32,TCAF1,ARHGAP24,DAPK1,PDCD6IP,MAMLD1,GOLT1B,FRY,FSD1L,PHF20L1,MBNL2,PAN3,EPB41,RASL12,DLC1,RGPD5,EFCAB2,DISC1,KIAA1841,TUBGCP4,LYVE1,ZNF638,LNX1,CCDC184,MUM1,NCKAP1L,LRRC75A,ITGAM,SYTL4,MARK1,LYPLAL1,MBD1,TM6SF1,NEK1,NOVA1,TBC1D25,SEMA5B,PLCB2,PCDH18,PURG,MAPKAP1,FSD1,PRKACB,CEP41,CNTLN,ZNF615,SH3TC2,RAP1GDS1,ZMAT4,ERI2,GTDC1,YY1AP1,RPS20,MEG3,RYR3,SATB1,CSRNP3,LRFN5,SCP2,FOXRED1,AMBRA1,WDR47,CCDC88A,SLC22A4,INTS9,SNRPN,SPP1,POGZ,NSFL1C,COBL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,MTMR14,BHLHB9,TSN,ANKRD20A2,TSC1,UBE2H,BCL2L13,ZBTB38,PRDM10,SLC17A7,FAM47E,RGS7BP,FZD3" MicroRNA hsa-miR-3200:mirSVR_lowEffct hsa-miR-3200:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.42E-55 1.36E-51 1.11E-54 1.03E-53 164 1068 "AS3MT,C3orf14,KLHL32,KIAA1211,CC2D2A,OGT,LCORL,SUGT1P4-STRA6LP-CCDC180,BCAS1,NCOA1,SLC4A4,EIF4G3,ADAM23,TTLL9,ADGRB3,CFLAR,SYNJ2,NAE1,IL33,SPAG9,CBLN1,USP2,P2RX6,SOCS6,B4GALT6,EPS15L1,ARMC8,WHRN,MAGED1,SLC35F1,HINFP,RGS6,SEC24C,ARHGEF10,APPL1,RUBCN,USP6NL,DCAF8,MATR3,SPOCK2,SPATA2,JAKMIP2,SGSM2,TMCC2,GRIN3A,DMD,USP3,NR1D2,DTNA,DTNB,EBF1,EDN1,APH1A,MBNL2,TMEM132E,ING4,HSD17B14,EPHB1,DENND4A,CDKL3,RRAGB,DLC1,FCGR1A,FGF1,HPCAL4,FOXF2,VTI1B,ANKFY1,EFCAB2,ST6GALNAC3,NSG1,MSANTD4,DISC1,GATM,TUBGCP4,SPIN1,PRUNE2,GPER1,GPR34,GRIA2,CLASRP,HNMT,IDH3B,ITGAM,NCOA7,PACRG,PIK3AP1,CLEC18A,MAN2A2,ZFYVE27,MARK1,MATN3,MBD1,MBNL1,MEIS1,NF1,NNAT,NTRK2,IGSF11,OXTR,GPR85,RETREG2,PRKAR1B,SAMD9,PTN,PTPRD,EML5,PTX3,CEP97,SH3TC2,SUSD4,RADX,GTDC1,FIGN,UBR7,C12orf49,EPHA10,KIAA0895L,MAPK12,SCN2B,PRCD,ARX,FERMT1,ST6GAL1,KANSL3,SLC9A5,EPC1,SNRPN,PDZD2,BDP1,SPTB,ATP10B,CLSTN2,SSTR1,ZC4H2,ZSCAN29,DNAJC9,PLCB1,C12orf76,MTCL1,TCF12,AP4E1,ASXL3,R3HDM1,PDSS1,VIPR2,CLDND1,RICTOR,ZIC1,ZNF708,ZNF28,ZNF138,CELF4,ZBTB38,ANKS1B,SLC38A1,MDH1B,PARP11,DOCK8,CASC15,RNF170,MSRB3,FAM198A,SPATA13" MicroRNA hsa-miR-758:mirSVR_highEffct hsa-miR-758:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.94E-55 1.65E-51 1.35E-54 1.24E-53 137 753 "ADD1,INTS2,CDC42BPA,MAP4K3,PHF12,DDO,NUMB,ATP2B2,ALDH7A1,PROM1,BMP7,DST,SCAPER,KALRN,PTBP2,CAST,SPAG9,RUNX1T1,MAGI1,UBE2L6,CFL2,CHN2,FBXO7,C4orf33,MAP4K4,AKAP6,FAM171B,SIPA1L1,VCAN,KIAA0040,APPL1,CYBB,LYPD1,WDR20,NR1D2,SLC25A18,ARRDC4,DTNA,E2F5,EDNRB,ANKRD46,RASGRP1,KLHL5,FAM13A,TLR7,F8,CLVS1,RPS6KC1,FCGR1A,GORAB,SEC24B,FER,SPSB4,SYNCRIP,NBEA,TMEM107,ZNF605,TVP23A,OGA,GAD1,MTHFD2,DISC1,STON1,RASSF8,HLF,HNMT,ZDHHC15,EID2B,TJAP1,MEIS1,MEIS2,MID1,DNHD1,PCSK1,SLC10A4,NALCN,STRN3,GRAMD1C,DIRAS2,RELN,PTCH1,MTMR10,ZNF615,RAD17,OXR1,RADX,GTDC1,RFX3,TMLHE,CARF,ROBO1,ZC3H14,TRAPPC13,RASA3,SLC14A1,CPEB4,MAST1,MBD5,ZNF415,FNBP1,CDK19,CLASP2,CLSTN2,LARP4,NEK4,SULF2,STXBP1,KLHL7,ADAMTS17,MTCL1,FAM208A,TBCEL,TRIM2,PUM2,GPRIN3,ZFPM2,TIAM1,TP53BP2,NPL,TRO,TTC3,GORASP1,ZNF28,NDRG4,TCEAL7,ZBTB38,ZNF177,FSTL5,RNF103,TUBA1A,NAV3,WNK2,SMIM8,HNRNPA3,PHTF2,FBXO36,FRMD6" MicroRNA hsa-miR-149*:mirSVR_highEffct hsa-miR-149*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.87E-55 2.17E-51 1.78E-54 1.64E-53 154 950 "VWA5B2,SYN3,ASIC1,EMILIN3,AP2A1,MTUS1,CARNS1,AMPH,LRFN1,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,SEMA4G,CDK13,EIF4G3,ATP6V1G2,NRP2,PROM1,SYNJ1,ARHGEF7,GPC2,CA8,CLDN10,CPNE6,PPT2,TPP1,CNTFR,AKAP6,WHRN,GAL3ST1,MROH8,CSF1,CSF1R,CSF2RA,CST3,DCAF4,BOC,KATNAL2,ZNF337,C2CD2L,KIF19,ACOT8,DTNA,DNAJB6,EDNRA,CNNM1,EIF4G2,EPHB1,RABEPK,DENND4A,SPEG,GMPR2,ZSCAN30,FGF11,FGFR1,IP6K2,AGAP2,SPECC1,GAD1,FAM120B,DISC1,AHDC1,GLYR1,AIFM3,LOXL3,FUT10,CCDC184,SERP2,CIT,KAT7,ATOH8,PADI2,FRMD5,ATXN2L,AGBL5,DHX35,LRRC75A,KIF5A,HECTD2,MAP6,COL28A1,ADAM22,NEK1,NF1,SETD4,DPY19L2P2,CDK18,PDE1B,SMOX,PMP22,PTK2,PTPRG,PTPRN,TMEM145,ZSCAN2,FAM66C,ERI2,MORC4,GTDC1,RGS12,RNASEL,GLDN,RPS6KA2,ATAT1,KCNIP1,NCBP3,FNIP1,SEC14L1,FERMT1,SYBU,SLC2A5,LIMS2,KANSL3,PKNOX2,KDM4D,SLC11A1,KBTBD4,SLC12A4,ZNF667,SMARCD3,IFT122,MYO16,KDM3A,DBNDD2,NFASC,STAU1,TTBK2,STAC2,SULF2,STXBP1,SUPT5H,SYN1,SYN2,SYP,ZFP90,SYNE1,TNS2,TIAM1,ACTR6,FAM124A,METTL3,RUNDC3B,RUSC1,KCNE5,SSBP2,ZKSCAN5,GORASP1,CCDC136,VLDLR,MEIS3,STOX2,NAV3,PDSS2,AP3B2" MicroRNA hsa-miR-299-5p:mirSVR_highEffct hsa-miR-299-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.13E-55 2.31E-51 1.89E-54 1.74E-53 126 637 "ABR,CLK4,NCKAP5,MTUS1,KLHL13,OSBPL8,ALCAM,LRCH2,PHF12,CASK,ZBTB10,CCAR2,EIF4G3,STX16,N4BP2L1,BACH1,RGS9,DST,SYNJ1,JAZF1,CD86,LRBA,SULT4A1,CNTN1,CREM,TRIM69,SOCS5,ERC2,DOCK4,HDAC9,LONRF1,KIAA0586,PABPC5,ARMCX2,DDX46,CPEB2,PDCD6IP,FAM78B,ABCC5,EDNRB,HIPK3,FSD1L,FAM13A,PHF20L1,ELN,CALCRL,DCTN4,ENPP6,GORAB,FGF14,UFM1,STAU2,ABLIM2,OGA,MEGF10,IQGAP2,AHDC1,GFRA2,GGT7,TCERG1,TOX3,MSL3,RAB40B,GPD2,GPR34,FAM19A2,HNMT,C9orf129,DHX35,ZIC5,RBPJ,LRRTM1,GATD1,MAT2A,KITLG,NF1,NPR2,SLC11A2,PCDH8,ENPP2,PFKFB2,NLGN3,KCTD15,PRIMPOL,LRP12,VPS13C,PTPRD,PTPRN2,RASGRF2,ZMAT4,GTDC1,RFX3,ZFHX4,ROBO1,PCMTD2,CCDC112,FNIP1,SGK1,MYO18A,CHD9,FHOD3,SIRT2,CCDC88A,SLC14A1,ELMO2,MBD5,PDZD2,TEX2,CDK19,POGZ,PLCB1,TACR1,DNMBP,FBXW11,PUM2,AKTIP,HEY1,TCEAL7,FSTL5,EML6,SLC30A4,EMSY,NAV3,KCNAB1,MPPE1,TRAM2-AS1" MicroRNA hsa-miR-3188:mirSVR_highEffct hsa-miR-3188:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.08E-55 2.84E-51 2.32E-54 2.14E-53 146 858 "C3orf14,FMNL2,OLMALINC,HECW2,AGT,AK2,TAOK1,FAM135A,ANK2,EP400,APLP1,IGDCC4,SPTBN4,ATP2A2,BACH1,KSR1,DST,ARHGEF7,GYG2,SGCE,CACNB4,THSD7A,PTBP2,SLC25A14,RUNX1T1,LDB2,MTMR7,ZMYM4,TIGD7,CLCN3,HECTD1,MAGED1,ABI3BP,GDA,CLIP3,SNCAIP,OSBPL3,BOC,HDAC9,DCAF8,MYEF2,NR1D2,CPEB2,MAMLD1,STX2,MRVI1,F8,CLVS1,ABCA8,FAM198B,GORAB,BAIAP2,FOXF2,SEMA4D,EFCAB2,KHDRBS3,ST6GALNAC3,STAU2,B4GALNT1,BRD8,CRCP,TNRC6A,TDRKH,CCDC184,GRIA2,GRIN2D,COQ10A,AGBL5,SHISA6,ICA1,KCND1,KCNF1,KTN1,PAXBP1,MAP4,AQP11,MEIS1,PPM1L,MITF,MYO7A,NELL2,NF1,NTRK3,PDE4B,ENPP2,GNG2,JAKMIP1,HYDIN,BDNF-AS,STK32A,NWD1,RADX,ZDHHC14,UBR7,SLC25A36,ZNF532,TMLHE,LRRK2,ABCA11P,CLIP1,FAM192A,ZFP30,CPEB3,SLA,WDR47,ZNF430,RCOR3,CABCOCO1,SNRPN,HECW1,ATP10B,NKAIN2,ERBIN,TTBK2,ADHFE1,ADAMTS17,TMEM150C,MTCL1,KLHL4,TCEA1,SYNE1,GPRIN3,RNF216P1,SIRT1,ZMAT3,SLC44A1,NR2E1,FAM124A,R3HDM1,NPL,TRIO,PPIL6,ZNF610,RPL7L1,OSBP2,TOM1L2,RICTOR,ZFP37,TRIM9,EML6,SLC38A1,NAV3,PDSS2,DOCK8,PHTF2,SENP7" MicroRNA hsa-miR-148b-3p:TargetScan hsa-miR-148b-3p TargetScan 5.39E-55 3.01E-51 2.46E-54 2.27E-53 120 577 "ACHE,CCDC85A,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,CDK13,MARCH3,NCOA1,ATP2A2,BCL7A,FUBP1,CABP7,CAMK2A,CAST,RUNX1T1,CERS5,CDC25B,NOG,CFL2,B4GALT6,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,CCDC144A,GAPVD1,ELMO1,RAB39B,DMPK,EDNRA,HIPK3,KLHL5,EGFR,EGR3,PAN3,EMX2,MTSS1L,ETV1,SCML2,MED12L,PRKAG2,FUT9,NEURL4,ARFIP1,AHDC1,PPARGC1A,KDM2B,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,IL6ST,CDH20,KCNN3,KIT,IPO5,AQP11,MITF,MPP2,ADAM22,MYO9A,NDP,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,PIK3C2A,PPP2R5E,KANSL1,CNNM2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,RXRA,SCN8A,MRAS,HSPA4L,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,NSD1,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,BCL2L13,KLC2,RICTOR,EML6,DPYSL5,RTN4,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-148a-3p:TargetScan hsa-miR-148a-3p TargetScan 5.39E-55 3.01E-51 2.46E-54 2.27E-53 120 577 "ACHE,CCDC85A,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,CDK13,MARCH3,NCOA1,ATP2A2,BCL7A,FUBP1,CABP7,CAMK2A,CAST,RUNX1T1,CERS5,CDC25B,NOG,CFL2,B4GALT6,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,CCDC144A,GAPVD1,ELMO1,RAB39B,DMPK,EDNRA,HIPK3,KLHL5,EGFR,EGR3,PAN3,EMX2,MTSS1L,ETV1,SCML2,MED12L,PRKAG2,FUT9,NEURL4,ARFIP1,AHDC1,PPARGC1A,KDM2B,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,IL6ST,CDH20,KCNN3,KIT,IPO5,AQP11,MITF,MPP2,ADAM22,MYO9A,NDP,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,PIK3C2A,PPP2R5E,KANSL1,CNNM2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,RXRA,SCN8A,MRAS,HSPA4L,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,NSD1,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,BCL2L13,KLC2,RICTOR,EML6,DPYSL5,RTN4,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-152-3p:TargetScan hsa-miR-152-3p TargetScan 5.39E-55 3.01E-51 2.46E-54 2.27E-53 120 577 "ACHE,CCDC85A,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,CDK13,MARCH3,NCOA1,ATP2A2,BCL7A,FUBP1,CABP7,CAMK2A,CAST,RUNX1T1,CERS5,CDC25B,NOG,CFL2,B4GALT6,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,CCDC144A,GAPVD1,ELMO1,RAB39B,DMPK,EDNRA,HIPK3,KLHL5,EGFR,EGR3,PAN3,EMX2,MTSS1L,ETV1,SCML2,MED12L,PRKAG2,FUT9,NEURL4,ARFIP1,AHDC1,PPARGC1A,KDM2B,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,IL6ST,CDH20,KCNN3,KIT,IPO5,AQP11,MITF,MPP2,ADAM22,MYO9A,NDP,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,PIK3C2A,PPP2R5E,KANSL1,CNNM2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,RXRA,SCN8A,MRAS,HSPA4L,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,NSD1,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,BCL2L13,KLC2,RICTOR,EML6,DPYSL5,RTN4,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-637:mirSVR_highEffct hsa-miR-637:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.25E-55 3.50E-51 2.85E-54 2.63E-53 122 598 "NDRG2,KLHL32,ADD2,CASKIN1,KIAA1324,CC2D2A,PKP4,UPRT,PCDHGB4,TTLL9,CASTOR3,CACNA1G,KALRN,PPT2,PICK1,SUMF2,LETMD1,AKAP5,SMARCAL1,MYRIP,CPS1,SEC31B,CLIP3,SEC24C,CSNK1G3,DCAF8,DGKG,RUSC2,SGSM2,DPH1,DTNB,DUSP9,AASDH,RASA4,IRAK4,CERCAM,COQ7,ERCC2,CDKL3,CLVS1,ST3GAL6,STRADA,FGF11,FGF14,FLT1,APOPT1,USP21,CELF1,ACSS1,NEU3,GCK,GLYR1,STARD3,GPD2,FUT10,LILRA2,PLCD4,GRIK5,RNF165,ADAMTS6,ATXN2L,AGBL5,CFAP126,LRRC75A,IDH3A,MBD1,GIT1,MYO9A,RTL5,IGSF11,PCDHGC3,PCSK5,NLGN3,PLCB2,PLTP,EPB41L4B,PILRA,PPP5C,PIGG,RAD51D,EXD2,ATAT1,ARX,FERMT1,ASAP3,FUZ,R3HDM2,NAPB,INAVA,UNC5B,TSPYL2,POGZ,SSPO,ZSCAN29,KANK1,SULF2,SEPT3,KLHL7,ARC,CAMTA1,TCF4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ARHGAP9,THRA,MTMR14,NUTM2A,RPL7L1,WNT7A,TRIM9,SMARCAD1,ITM2C,RNF170" MicroRNA "GTGCCTT,MIR-506:MSigDB" "GTGCCTT,MIR-506:MSigDB" MSigDB 7.72E-55 4.32E-51 3.52E-54 3.24E-53 129 672 "FMNL2,PLEKHH1,ESYT2,CASKIN1,PCDH19,OSBPL8,AK2,SEMA6A,ZNF687,CDC14B,SFMBT2,CHRD,ATP1A1,DPY19L3,NRP2,MYRF,PTBP2,USP6,CDH2,LHX2,QKI,TMEM184B,ARHGEF6,AKAP6,MYRIP,CLOCK,LRIG1,GALNT9,SOCS5,SLITRK5,PLCXD3,HDAC9,MYADM,GAPVD1,HDAC4,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,GRIN3A,RCAN1,E2F5,EDNRB,PAN3,EYA1,SUCO,PCYOX1,IQGAP2,SEPT9,ARFIP1,KIAA1958,GPT2,GRIA2,CACFD1,RNF165,KAT7,BACH2,NEGR1,MYLK2,INSM1,ITGA7,HECTD2,MAT2A,MITF,NFIX,NME4,NRCAM,PCDH8,PCDH9,PDE4B,RETREG1,XRN1,PLEC,SMOX,SH3KBP1,MAPK7,TMEM104,USP47,RAD17,DUSP15,UBR7,RXRA,RYR3,SEMA6D,SCN2B,SMPD3,GALNT10,SGK1,KIF16B,SHC4,FAM81A,ARHGEF40,SLC12A2,BTBD7,ATF7IP,LIMCH1,FNBP1,LMO3,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TPCN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,NR2C2,SLC35A4,UBE3A,USP1,CLDND1,USP32P2,FSTL5,ZNF189,SPIRE1,ZNF213,SMARCAD1,EVI5,ADAMTS9,ITM2C,TMEM63C,ST8SIA2" MicroRNA hsa-miR-921:mirSVR_highEffct hsa-miR-921:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.22E-55 5.16E-51 4.20E-54 3.87E-53 129 673 "NDRG2,TMCC3,KIAA1211,ADRB2,RTL9,ADGRF5,C1QTNF3,ALCAM,FAM135A,OGT,EP400,MAP4K3,UPRT,IGDCC4,ARHGDIA,ADAM23,ADGRB3,MPDZ,MTMR2,CBR1,METTL6,RCBTB2,MS4A7,B4GALT6,TPP1,C4orf33,HECTD1,CNRIP1,LRRC3B,CST3,UBXN2A,PNPLA8,PUM1,ZSCAN23,MYADM,KIAA0586,SPOCK3,CHRDL1,DTNA,EDNRB,SUGP2,MBNL2,DCTN4,ADGRV1,EYA1,F8,GTF2IRD2,SEC23B,STAMBP,MSANTD4,ZMAT1,DISC1,INPP5K,GHR,KAT7,ZBTB49,AP4S1,ADAMTS6,GUCY1B1,HAS2,ZHX1,MIER3,VSIG4,HSF2,SHISA6,MSL1,IDH3A,NKD1,ZNF678,SLC35G1,KCNN2,KCNN3,KIF5A,MARK1,MEIS2,KITLG,NEK1,TBC1D25,GPR137C,PCSK5,ZFYVE21,FAM216A,JAKMIP1,PPM1B,KANSL1,DIRAS2,BDNF-AS,TMEM260,PTPRB,EML5,ACSM5,QDPR,PID1,PCMTD2,NCBP3,KIF21A,SHC4,SLC6A8,SLC6A11,CCDC88A,BTBD7,SNCA,ZNF415,FAM219A,KDM3A,SP4,KDM4C,CDK19,LMO3,CLASP2,TROVE2,NKAIN2,SEPT8,ADGRL3,DMXL2,TMPO,TPM1,SYNPO2,STXBP4,MTCH1,RICTOR,GUSBP1,ZNF711,AGMO,FSTL5,SMARCAD1,TIGD6,RNF170,FAM198A" MicroRNA hsa-miR-371-5p:mirSVR_highEffct hsa-miR-371-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.75E-55 5.45E-51 4.44E-54 4.09E-53 159 1017 "CCDC85A,PTCHD1,DPY19L2P4,HACE1,NME5,CC2D2A,FAM135A,CDC42BPA,PHF12,PKP4,PARG,ASGR1,SLC2A11,SEC11C,NRP2,GPC2,PTBP2,CAMK2G,SLC25A14,KRIT1,DGKI,MAGI1,CFL2,NDST3,RAB33A,CNGA3,COL9A1,SLC4A8,CS,AATK,SOCS5,CST3,DZIP3,CYBB,DOCK4,DGKB,TMEM170A,IP6K1,DBI,ZNF804A,SNAP91,FAM107B,DMTF1,SLC25A18,EDN3,ANKRD46,HIPK3,MBNL2,COPS4,CALCRL,RCAN2,EPHB1,SRRM1,PIPOX,ACSL4,FKTN,GORAB,GTF2IRD2,SUCO,UFM1,PDLIM5,STAMBP,STAU2,GABRA3,RAPGEF6,MTHFD2,DISC1,KIAA1841,TUBGCP4,TNRC6A,GLUL,STARD3,KDM2B,PRRC2B,TDRKH,GRIA2,DIDO1,FAM19A2,SOX21,ZDHHC15,SMAP1,ZIC5,METTL21A,CYP27C1,KTN1,ZNF667-AS1,MAP4,MEIS1,SRSF12,AFDN,COL28A1,MYCN,MYO9A,NTRK2,NUCB2,DPY19L2P2,PCDH8,CDK18,PRTG,PCDH18,EXOSC10,APTX,BDNF-AS,PEX2,TMEM255A,FAM184A,RADX,NUDT11,RNASEL,CCDC25,RPS6KA2,R3HDM2,PPP4R3A,KANSL3,CPEB4,IFT122,SNAP25,MBD5,CABCOCO1,USP33,SOX3,MYCBP2,LMO3,NKAIN2,SS18,SYNE2,PLCB1,SYN2,TBCEL,ATMIN,SATB2,SYNE1,PCDHB7,PUM2,SIK3,TLR4,R3HDM1,CSMD1,ZNF346,BCL2L13,ZNF24,TRIM9,EML6,ANKS1B,DHX33,PRDM10,ADAMTS9,VPS35L,NAV3,AMN1,DOCK8,RTN4,UBE3B,FAM219B,NLRP3,RNF170,IFT88,RNF146,FAM198A" MicroRNA hsa-miR-142-5p:TargetScan hsa-miR-142-5p TargetScan 1.10E-54 6.16E-51 5.01E-54 4.61E-53 129 674 "RNF150,HECW2,OSBPL6,ALCAM,ABCD2,MAP4K3,GAS7,CASK,MTMR2,CACNA1B,CALM1,CAMK2A,CAST,ISPD,RUNX1T1,LDB2,KRIT1,LRWD1,NOG,QKI,ARHGEF6,CNTN1,ARMC8,AKAP5,FAM171B,CLOCK,C2CD2,CRY2,CNTNAP2,APPL1,PUM1,FAM131B,MAML1,DNAL1,RHOBTB1,SACS,MTX3,FAM107B,DMD,CDON,CPEB2,ABCC5,EDNRB,EGR3,CERCAM,RGS17,MTSS1L,ETV1,MED12L,FGF12,NBEA,PDLIM5,FAM49B,ATP2C1,NSG1,MPP6,GALNT15,GPR75,LUZP2,GPR37,DIDO1,CIT,RNF165,BVES,FRMD5,MIER3,DHX35,CELF5,IGF1,IL6ST,KCNB1,KCNQ3,KIT,IPO5,CHIC1,LRP1B,MEIS1,MEIS2,KITLG,MITF,DBNL,MXI1,MYCN,MYO9A,NFE2L2,PAX6,LRP12,SCHIP1,PPP3CA,CNNM2,PTPRB,PTPRD,CEP97,RBBP6,RBBP8,REV3L,FIGN,RIC8B,PBRM1,RNH1,ROBO1,RTN1,FNIP1,HSPA4L,CPEB3,CHD9,CCDC92,EPN2,ARHGEF40,BTBD7,MBD5,CLSTN2,NECAB1,ANKRD12,FAM189A1,PUM2,KAT6B,RGMB,ELP5,FAM155A,CADM2,PRDM8,PRDM10,FIP1L1,FAM219B,JMJD1C,MSRB3,NETO2,NETO1" MicroRNA hsa-miR-206:TargetScan hsa-miR-206 TargetScan 1.12E-54 6.29E-51 5.10E-54 4.70E-53 125 632 "RALGAPA1,NDRG3,RNF157,RNF150,HECW2,HACE1,OSBPL8,MAP4K3,CASK,ARNTL,NCOA1,ATP6V0A1,BCL7A,NRP2,BMPR1B,FUBP1,CA8,CA12,CALM1,KALRN,CDR1,CLCN3,CLTC,QKI,CNN3,BAG4,CLOCK,CREM,AKAP12,RNF14,CSF1,RIMS4,PLXNA4,KIAA0040,HDAC4,MATR3,DGKG,AIF1L,DNAL1,MYEF2,ELMO1,FAM107B,DMPK,CDON,DPH1,ECM2,E2F5,EDN1,PHC2,HIPK3,HEYL,KLHL5,CELSR3,PLEKHA1,EMX2,EPB41L2,RCAN2,RABEPK,AMOTL2,SEC23B,NBEA,CPLX2,ARFIP1,PCDH17,GLYR1,KDM2B,GPD2,RNF165,KAT7,BACH2,HMGCR,IGF1,IL6ST,KIF2A,KTN1,MEIS1,PPM1L,GIT1,DBNL,MYO9A,NRCAM,GPR137C,PAX6,GPR85,PFKFB2,PIK3C2A,EPB41L4B,PRKACB,MAPK3,CNNM2,PTPRD,PTPRG,PEX2,MSANTD2,GTDC1,RFX3,FBXW7,KCNIP3,ATXN2,MRAS,FAM102A,MYO18A,FNDC3A,PEX26,EPC1,MAPKBP1,RBM26,LARP4,NXT2,DIP2A,NECAB1,NSD1,GPRIN3,DICER1,ARL10,ASXL3,LRRC8A,KAT6B,FAM155A,RICTOR,KAT6A,HNRNPA3,ADAMTSL3,NETO1,GAN" MicroRNA hsa-miR-1-3p:TargetScan hsa-miR-1-3p TargetScan 1.12E-54 6.29E-51 5.10E-54 4.70E-53 125 632 "RALGAPA1,NDRG3,RNF157,RNF150,HECW2,HACE1,OSBPL8,MAP4K3,CASK,ARNTL,NCOA1,ATP6V0A1,BCL7A,NRP2,BMPR1B,FUBP1,CA8,CA12,CALM1,KALRN,CDR1,CLCN3,CLTC,QKI,CNN3,BAG4,CLOCK,CREM,AKAP12,RNF14,CSF1,RIMS4,PLXNA4,KIAA0040,HDAC4,MATR3,DGKG,AIF1L,DNAL1,MYEF2,ELMO1,FAM107B,DMPK,CDON,DPH1,ECM2,E2F5,EDN1,PHC2,HIPK3,HEYL,KLHL5,CELSR3,PLEKHA1,EMX2,EPB41L2,RCAN2,RABEPK,AMOTL2,SEC23B,NBEA,CPLX2,ARFIP1,PCDH17,GLYR1,KDM2B,GPD2,RNF165,KAT7,BACH2,HMGCR,IGF1,IL6ST,KIF2A,KTN1,MEIS1,PPM1L,GIT1,DBNL,MYO9A,NRCAM,GPR137C,PAX6,GPR85,PFKFB2,PIK3C2A,EPB41L4B,PRKACB,MAPK3,CNNM2,PTPRD,PTPRG,PEX2,MSANTD2,GTDC1,RFX3,FBXW7,KCNIP3,ATXN2,MRAS,FAM102A,MYO18A,FNDC3A,PEX26,EPC1,MAPKBP1,RBM26,LARP4,NXT2,DIP2A,NECAB1,NSD1,GPRIN3,DICER1,ARL10,ASXL3,LRRC8A,KAT6B,FAM155A,RICTOR,KAT6A,HNRNPA3,ADAMTSL3,NETO1,GAN" MicroRNA hsa-miR-599:mirSVR_highEffct hsa-miR-599:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.30E-54 7.26E-51 5.88E-54 5.42E-53 150 911 "ACADM,ABHD6,KLHL32,SLC24A4,AK2,OGT,PHF12,MAGEE2,UPRT,NUMB,EIF4G3,ATP1B3,STX16,RIPK1,ADAM23,TTLL9,LINC00847,LRBA,MAGI1,CHGB,CHN2,B4GALT6,EPS15L1,NRXN3,ABCG2,CNTFR,AKAP7,AKAP6,CNRIP1,CLOCK,CRMP1,ANKRD44,TRIM69,CSF2RA,SEC24C,PDE4DIP,ERC2,LIN54,DAPK1,ARRDC4,SNX29,EDN1,SEMA3D,SUGP2,EPB41,RCAN2,LRRC17,TAOK3,BAIAP2,HPCAL4,AGAP2,PSD2,SMC2,PDLIM5,KHDRBS3,BRSK1,ERAP1,TMEM8B,C15orf41,DISC1,KIAA1841,ARFIP1,ADAM28,BRD8,COPS8,ZNF638,LUZP2,FERMT2,GPD2,PRUNE2,FUT10,ATP2B1-AS1,PRDM5,SHISA6,IDH3A,IGF1,RBPJ,STXBP5,MAP4,LYPLAL1,MBNL1,MBP,MXI1,LAYN,NF1,SLC11A2,NTRK2,PCSK5,PDE1C,PDE3A,PDE4B,PDE4D,PIK3C2A,GPSM2,PMP22,EPB41L4B,MAPK9,MAPK10,VPS13C,BDNF-AS,PTPRD,PBRM1,EXD2,CARF,NEK11,FBXW7,PTGR2,RTN1,ZFP30,FERMT1,SHC4,SEC31A,SEPHS1,ANKRD36,SNCA,SNRPN,MYCBP2,CLASP2,SS18,PRRC2C,ARHGEF9,TACC1,FAM208A,ATMIN,SATB2,ZEB1,TCF12,CLASP1,PCDHB3,MTMR14,NR2E1,SYNPO2,AMACR,TRO,PPIL6,VSNL1,CLDND1,MKRN3,ZNF138,ANKS1B,PRTFDC1,FIP1L1,WNK2,FAM13C,DOCK8,ST7,KAT6A,SMIM8,JMJD1C,SPATA13" MicroRNA hsa-miR-1237:mirSVR_highEffct hsa-miR-1237:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-54 8.12E-51 6.58E-54 6.06E-53 142 819 "NCKAP5,KDM5D,PWWP2A,RNF150,ESYT2,ADRB2,TBC1D14,SPOP,FAM135A,OGT,FAM131A,PHYHD1,USP37,EIF4G3,ADAM23,TTLL9,BBS2,BCHE,GYG2,KALRN,HIP1R,DGKI,PICK1,IQCK,FAM149A,SLC4A8,AHCTF1,ANKRD44,GDA,PDE4DIP,CTH,GREB1,PPP6R2,CYBB,KATNAL2,ARHGAP24,PITPNC1,SPATA2,ZBTB24,HEPH,MYEF2,B3GAT3,FBXL5,PLPPR4,WDR20,DMD,DMTF1,ABCC5,EDNRA,SEMA3D,RABEPK,SIRPB1,NSRP1,RPS6KC1,SCML2,PRMT5,FGF1,DCTN2,ZNF605,CELF1,ST6GALNAC3,ZMAT1,GALNT15,TMEM8B,TCERG1,SPIN1,GLYR1,ZNF638,GPD2,FUT10,STMN2,DIDO1,PRDM5,SCIN,CDH20,KCNN2,CREG2,KIFC3,KTN1,PIK3AP1,MAT2A,MATN2,KCTD6,LAYN,CNOT4,NOVA1,OGG1,CDK18,PDE3A,KANSL1,FITM2,GRAMD1C,APTX,CNTLN,PTPRE,PTPRO,CEP97,SUSD4,RBBP8,FIGN,RFX2,RGS3,ZFHX4,ELP2,NEK11,ZNF671,ATAT1,RYR3,TRAPPC13,ZFP2,CASC3,SHC4,HKDC1,CNKSR2,ARHGEF40,SLC14A1,CPEB4,ANKRD36,SNRPN,ZC3H13,ZC4H2,NKAIN2,SS18,NSFL1C,NECAB1,SYN2,EXOC7,HIF3A,AP4E1,TIMP4,NR2E1,TPM1,BCL2L13,RBFOX3,ZIC2,STOX2,RNF103,NAV3,PCBP4,TMEM63C,RNF170,FXR1" MicroRNA hsa-miR-140-3p:mirSVR_highEffct hsa-miR-140-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-54 9.99E-51 8.09E-54 7.45E-53 147 878 "KDM5D,NDRG3,AP2A2,AMPD3,DPY19L3,BMPR1B,DST,CA8,KALRN,SLC25A14,CERS5,USP6,CD38,C1orf52,DGKI,AP4M1,MAGI1,QKI,MAP4K4,IQCK,SUMF2,MYRIP,ZFP28,SLC35F1,SEC31B,ENTPD4,CSF1,SOCS5,CCDC144A,MYADM,ZFYVE16,SV2B,GRIN3A,DNM1,NR1D2,CPEB2,DMTF1,FARSB,GOLT1B,AASDH,EDNRA,YAF2,PHF20L1,KMT5B,ASB3,COQ7,CLVS1,NSRP1,FAM198B,SCML2,POLR1B,SYNCRIP,STAMBP,ATP6V1H,KHDRBS3,SARAF,CHL1,SPIN1,MSL3,ZNF638,DCLK2,LILRA2,DIDO1,GRM2,ARHGAP36,MIER3,HLF,HNF4G,HNMT,HSF2,KCNB1,LAMP2,NCOA7,MARK3,MBD1,MEIS2,KCTD6,MIA2,NEK1,NF1,NFYA,NOVA1,DNHD1,TBC1D25,OCRL,PCDH8,SLC10A4,OLA1,PKM,PLCB2,PURG,SCHIP1,MAGEL2,ING3,EPB41L4B,SH3KBP1,RASGEF1B,PKIA,VPS13C,CNTLN,ZIK1,NWD1,ZNF493,NUDT11,CCDC82,CARF,ROBO2,YY1AP1,CLIP1,SCP2,KIF21A,PPP4R3A,SLC6A11,SLC12A4,ELMO2,SMARCC2,SNAP25,ZNF415,DOK5,SP4,SYNE2,VPS13A,PLCB1,TCEA1,TCF4,SIN3B,CUX2,ZEB1,DOCK9,CCDC173,SIRT1,ZFPM2,HEY1,ERCC6L2,PRRT1,UGT8,USP1,WIPF1,P2RY12,RICTOR,ZBTB38,SLC30A3,STOX2,NAV3,PDSS2,FAM13C,FRMD6" MicroRNA "TGCACTT,MIR-519C:MSigDB" "TGCACTT,MIR-519C:MSigDB" MSigDB 1.92E-54 1.07E-50 8.67E-54 7.99E-53 103 421 "SLC24A4,OGT,LRCH2,RASL11B,NRP2,MYRF,USP6,CFL2,SOCS6,QKI,AHCTF1,GDA,LRIG1,PPP6R2,ARHGAP24,MAML1,FBXL5,SACS,WDR20,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,PTPRT,SOX21,HAS2,IGF1,KCND2,KCNN2,KIF5A,LAMP2,CAMK2N2,MAP4,MBNL1,MYT1,NBL1,NF1,NFIX,CNOT4,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,CEP97,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SYBU,CCDC88A,BTBD7,TSPYL2,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,R3HDM1,UBE3A,VLDLR,RICTOR,PCDH20,USP32P2,FSTL5,MAP3K12,EMSY,WNK3,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA "TGCACTT,MIR-519A:MSigDB" "TGCACTT,MIR-519A:MSigDB" MSigDB 1.92E-54 1.07E-50 8.67E-54 7.99E-53 103 421 "SLC24A4,OGT,LRCH2,RASL11B,NRP2,MYRF,USP6,CFL2,SOCS6,QKI,AHCTF1,GDA,LRIG1,PPP6R2,ARHGAP24,MAML1,FBXL5,SACS,WDR20,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,PTPRT,SOX21,HAS2,IGF1,KCND2,KCNN2,KIF5A,LAMP2,CAMK2N2,MAP4,MBNL1,MYT1,NBL1,NF1,NFIX,CNOT4,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,CEP97,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SYBU,CCDC88A,BTBD7,TSPYL2,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,R3HDM1,UBE3A,VLDLR,RICTOR,PCDH20,USP32P2,FSTL5,MAP3K12,EMSY,WNK3,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA "TGCACTT,MIR-519B:MSigDB" "TGCACTT,MIR-519B:MSigDB" MSigDB 1.92E-54 1.07E-50 8.67E-54 7.99E-53 103 421 "SLC24A4,OGT,LRCH2,RASL11B,NRP2,MYRF,USP6,CFL2,SOCS6,QKI,AHCTF1,GDA,LRIG1,PPP6R2,ARHGAP24,MAML1,FBXL5,SACS,WDR20,USP3,CPEB2,DPYSL2,DNAJB6,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,PTPRT,SOX21,HAS2,IGF1,KCND2,KCNN2,KIF5A,LAMP2,CAMK2N2,MAP4,MBNL1,MYT1,NBL1,NF1,NFIX,CNOT4,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,CEP97,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SYBU,CCDC88A,BTBD7,TSPYL2,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,R3HDM1,UBE3A,VLDLR,RICTOR,PCDH20,USP32P2,FSTL5,MAP3K12,EMSY,WNK3,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA hsa-miR-3175:mirSVR_highEffct hsa-miR-3175:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-54 1.16E-50 9.38E-54 8.63E-53 152 938 "CLK4,KDM5D,CCDC85A,ADD2,DPY19L2P4,SEMA6A,SPOP,TNRC6C,CDK10,RGS20,LINC00173,CCAR2,SLC2A11,DPY19L3,CARMIL3,MPDZ,KALRN,CAST,PPT2,ABCG2,CCDC151,CNTN1,ARMC8,SUMF2,CPS1,GDA,VCAN,SLITRK5,DZIP3,GREB1,TCAF1,ZNF337,TMEM170A,SPOCK2,SPOCK3,NYAP1,DOCK2,DTNA,DTNB,FIS1,SEZ6L2,PHC2,APH1A,TMEM35A,PAN3,ENO2,ERBB2,ANKMY1,SIRPB1,ZNF461,PTK2B,KAT8,FGF1,FGF12,POLK,AKAP3,NEURL4,MEGF11,GABRA3,B4GALNT1,MTHFD2,LRRC37A6P,SPIN1,LOXL3,GPD1,CCDC184,PLCD4,CLASRP,RNF165,UBE2QL1,SHISA6,IDH3B,NME9,SLC35G1,KCNN3,CREG2,CAMK2N2,STMN1,MARK1,AFDN,GIT1,LAYN,FXYD7,NNAT,NOVA1,OGG1,CLDN11,CDK18,PDE1B,PCDH18,SCHIP1,C19orf57,PRKACB,KLK6,QRICH1,PTPRH,RAP1GDS1,PRRT2,MORC4,SUGCT,SETD5,C12orf49,CCDC102B,SPIN3,ADAL,TCP11L1,CLIP1,SEMA6D,SCN2B,TRA2B,PPM1E,ARX,FERMT1,SHC4,FBXO11,DHX30,PKNOX2,SLC11A1,ELMO2,SLC22A4,SMARCD3,FNBP1,ZSWIM8,UHRF1BP1L,TSPYL2,ATP10B,POGZ,STAU1,ELOVL4,STXBP1,SYN2,WSCD1,TPCN2,PCDHB4,OBSL1,ZMAT3,AKTIP,NUTM2A,SSBP2,UBE3A,UBTF,UCHL1,OSBP2,SLC30A3,SLC17A7,PPP1R3F,PCBP4,WNK3,PHTF2,TRAM2-AS1,NETO1,JPH3" MicroRNA hsa-miR-138-5p:TargetScan hsa-miR-138-5p TargetScan 2.16E-54 1.21E-50 9.73E-54 8.96E-53 110 486 "PWWP2A,RNF150,PPFIA4,GAS7,ARRB1,NCOA1,CCAR2,AZGP1,JAZF1,CACNA1A,CACNA2D1,HAP1,CBFA2T2,CNOT8,IGLON5,NRG2,CLOCK,RIMS4,PLXNA4,FAM169A,PITPNM3,RIMS2,HDAC4,KIF26A,MAML1,SCRN1,IP6K1,MYEF2,DNAJB6,EBF1,HIPK3,CELSR3,APH1A,EGFR,PAN3,RCAN2,GPHN,ERBB4,CLVS1,ANKFY1,PSD2,NBEA,CINP,MEGF11,AHDC1,PPARGC1A,KIAA1958,FERMT2,PCLO,BVES,RASSF8,MIER3,CELF5,RBPJ,KCNK3,LIMS1,PPM1L,AFF1,GIT1,MSI1,HS6ST3,NFIX,NNAT,NOVA1,NOVA2,NPTX1,PDE3A,GNG2,FSD1,RELN,PIGG,PTK2,NKAIN1,MARCH1,FIGN,ROBO1,CLIP1,SCN8A,MRAS,HSPA4L,ARHGEF40,KBTBD4,LIMCH1,MAPKBP1,KIF13A,PEG10,IQSEC2,CDK19,CAMTA2,MPRIP,KANK1,NSFL1C,RHBDL3,KIAA0930,GPRIN3,ARL10,CBX5,ASXL3,KAT6B,OSBP2,MGAT5B,LGI4,PPP1R3F,ITM2C,KAT6A,FAM219B,ADAMTSL3,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-938:mirSVR_lowEffct hsa-miR-938:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-54 2.05E-50 1.66E-53 1.52E-52 142 825 "RNF157,PWWP2A,PTCHD1,HECW2,KIAA1324,AK2,ZNF578,HFM1,C1QTNF3,ALCAM,ZFAT,FAM131A,CDK13,MARK4,BID,CFLAR,KALRN,RUNX1T1,USP6,CHGB,SRP14-AS1,AKAP6,RCHY1,HAPLN1,OSBPL3,RIMS4,CNTNAP2,RHOBTB1,USP3,DPH1,ECM2,DNM1L,E2F6,WDPCP,FRY,PHF20L1,KCTD3,ACSL4,ZSCAN30,GORAB,FGF14,PCYOX1,C2orf88,PDLIM5,ATP2C1,ZNF605,CELF1,TVP23A,ALDH1L1,ZNF638,RAB40B,PRUNE2,GRIK4,GRIN2C,AP4S1,PSIP1,GABARAPL2,AGFG1,HSPA1L,SHISA6,GPR62,KHK,KIF2A,KIF5A,SYTL4,PIK3AP1,MBD1,LRP1B,MEIS1,MEIS2,MGAT3,MID1,AFDN,ZNF862,ALDH1L2,CNOT4,PCSK5,GPSM2,PLXNB1,LRP12,EXOSC10,RASGEF1B,PKIA,EPDR1,GDPD2,SNRK,TMEM260,PTPRB,C1orf109,RIPOR1,ZSCAN2,RADX,GAL3ST4,TRIM68,RGS4,CCDC102B,GLDN,LRRK2,ATAT1,NCBP3,CSRNP3,SCN2B,NLGN1,WDR37,EPN2,DHX30,SLC6A11,SEPHS1,SLC9A5,CXXC4,SOX11,HECW1,ATP10B,CLSTN2,SS18,CEP68,MTCL1,PDLIM2,KLHL4,TCF4,TPCN2,TRIM2,SYNE1,USP32P1,FAM200B,TK2,RIMBP2,KAT6B,RGMB,TRPS1,UBE3A,PLPPR2,RBFOX3,RICTOR,LGI4,TMEM237,SPIRE1,FTSJ1,GAL3ST3,FAM13C,CASC15,FRMD6" MicroRNA hsa-miR-199b-5p:mirSVR_highEffct hsa-miR-199b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.74E-54 2.09E-50 1.68E-53 1.55E-52 147 883 "RALGAPA1,KCNH8,ASPHD1,KLHL32,CCDC85A,PTCHD1,OGT,LRCH2,MAP4K3,PHF12,APOC1,PPFIA3,FUBP1,JAZF1,DDR1,KALRN,NFS1,CERS5,LRRFIP1,LARGE1,CCPG1,CFL2,COPB2,CHN2,CNOT8,CLTC,FAM149A,SLC4A8,BAG4,PREPL,HAPLN1,RGS6,UBXN2A,RUBCN,CYBB,HDAC9,GPRASP1,GAPVD1,RASSF2,TBC1D5,MYEF2,KIAA0753,SACS,FAM107B,E2F6,TSPAN5,OPTN,PAN3,USPL1,SRRM1,RACK1,FDFT1,TMEM164,SYNCRIP,IQCG,SEMA4D,SLC37A3,NBEA,TMEM107,ATP6V1H,NSG1,SARAF,GAD1,ZNF559,NEU3,GCNT2,SULT1C4,CSDC2,PPARGC1A,DBF4,TOX3,GLUL,GPD2,FUT10,GRIA2,PLCD4,PRDM5,FAM19A2,AGBL5,MSL1,SLC35G1,METTL21A,KCND2,KCNH2,KIT,LAMP2,PAXBP1,SYTL4,NCOA7,ZFYVE27,MAT2A,MBNL1,MBP,MEIS2,GIT1,MXI1,NF1,PDE4B,SLC10A4,PFKFB2,PCDH18,TRHDE,FA2H,PRKAB2,PIGG,MTMR10,ZNF844,MARCH1,CEP97,SUSD4,FIGN,ROBO2,RORB,ELP2,MRAP2,NEK11,KCNIP1,CLIP1,SATB1,ZFP2,KIF21A,NLGN1,BTBD7,RCOR3,LARP4,NXT2,ZSCAN29,ADHFE1,ZEB1,DNAH7,SIRT1,ERCC6L2,TMPO,RUSC1,TSC1,TST,HIRA,XRCC4,PCDH20,ZNF19,PCBP1-AS1,MFF,STOX2,WNK3,FAM13C,PHTF2,CASC15" MicroRNA hsa-miR-215:mirSVR_lowEffct hsa-miR-215:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.22E-54 2.36E-50 1.90E-53 1.75E-52 153 955 "ABHD6,KLHL32,GALNT16,TMCC3,PWWP2A,HACE1,AMPD3,PPP4R4,N4BP2L1,DPY19L3,DOCK11,DNAJC27-AS1,ST3GAL5,SYNJ2,GYG2,CACNA1I,LURAP1,PTBP2,DLGAP1,NOG,SOCS6,CHN2,FBXO7,RCHY1,SMARCAL1,SEC31B,ANKRD44,TRIM69,IPCEF1,VCAN,APPL1,CTH,GREB1,ARHGAP24,DCAF8,IST1,DNAL1,JAKMIP2,ZBTB24,RHOBTB1,CDON,CASP8AP2,DPYSL2,KRBA2,ANKRD46,TMTC1,YAF2,MRVI1,REEP2,CEP78,STRADA,FER,FGFR1,FLNC,FLT1,EFCAB2,APOPT1,STAU2,SARAF,OGA,ZMAT1,MEGF10,IP6K3,DISC1,MALT1,SPIN1,GLYR1,RASSF8,ARHGAP36,CPT1C,SHISA6,SMAP1,IGF1,GAREM2,IL6ST,KCNJ5,KCNK3,CREG2,CYP27C1,TTYH2,MAN2A2,MEF2C,MEIS1,THYN1,MYO6,MYO9A,RTL5,ZC3H12B,NEFM,NOVA1,SLC11A2,OPA1,CNTN3,SLC10A4,RETREG1,PURG,RETREG2,TATDN3,PPP2R2C,PRKACB,STK32A,ZSCAN32,PTPRE,TTC13,GTDC1,SLC25A36,RNASEL,ZFHX4,CCDC25,CCDC102B,RPE,GLDN,LRRK2,SATB1,SCAF8,ASAP3,NUBPL,PEX26,NAPB,ATF7IP,ZNF667,SMARCA4,INAVA,SNRPN,SP4,NMNAT2,MYCBP2,KDM4C,RBM26,SPART,LARP4,NECAB1,MTCL1,CAMTA1,TAL1,NSD1,RGMB,SYNPO2,METTL3,RPL7L1,CLEC2L,USP1,RICTOR,ZNF708,ZNF24,ZBTB38,ANKS1B,EMSY,PDSS2,HNRNPA3,PHTF2,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-192:mirSVR_lowEffct hsa-miR-192:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.22E-54 2.36E-50 1.90E-53 1.75E-52 153 955 "ABHD6,KLHL32,GALNT16,TMCC3,PWWP2A,HACE1,AMPD3,PPP4R4,N4BP2L1,DPY19L3,DOCK11,DNAJC27-AS1,ST3GAL5,SYNJ2,GYG2,CACNA1I,LURAP1,PTBP2,DLGAP1,NOG,SOCS6,CHN2,FBXO7,RCHY1,SMARCAL1,SEC31B,ANKRD44,TRIM69,IPCEF1,VCAN,APPL1,CTH,GREB1,ARHGAP24,DCAF8,IST1,DNAL1,JAKMIP2,ZBTB24,RHOBTB1,CDON,CASP8AP2,DPYSL2,KRBA2,ANKRD46,TMTC1,YAF2,MRVI1,REEP2,CEP78,STRADA,FER,FGFR1,FLNC,FLT1,EFCAB2,APOPT1,STAU2,SARAF,OGA,ZMAT1,MEGF10,IP6K3,DISC1,MALT1,SPIN1,GLYR1,RASSF8,ARHGAP36,CPT1C,SHISA6,SMAP1,IGF1,GAREM2,IL6ST,KCNJ5,KCNK3,CREG2,CYP27C1,TTYH2,MAN2A2,MEF2C,MEIS1,THYN1,MYO6,MYO9A,RTL5,ZC3H12B,NEFM,NOVA1,SLC11A2,OPA1,CNTN3,SLC10A4,RETREG1,PURG,RETREG2,TATDN3,PPP2R2C,PRKACB,STK32A,ZSCAN32,PTPRE,TTC13,GTDC1,SLC25A36,RNASEL,ZFHX4,CCDC25,CCDC102B,RPE,GLDN,LRRK2,SATB1,SCAF8,ASAP3,NUBPL,PEX26,NAPB,ATF7IP,ZNF667,SMARCA4,INAVA,SNRPN,SP4,NMNAT2,MYCBP2,KDM4C,RBM26,SPART,LARP4,NECAB1,MTCL1,CAMTA1,TAL1,NSD1,RGMB,SYNPO2,METTL3,RPL7L1,CLEC2L,USP1,RICTOR,ZNF708,ZNF24,ZBTB38,ANKS1B,EMSY,PDSS2,HNRNPA3,PHTF2,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-101*:mirSVR_highEffct hsa-miR-101*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.74E-54 2.65E-50 2.13E-53 1.96E-52 150 920 "BEND6,KCTD16,WDR35,ADGRF5,ALCAM,FAM135A,LRCH2,APAF1,PRX,CASK,N4BP2L1,ATP6V1G2,ARHGEF7,IL33,KALRN,SLC25A14,CAST,CBFA2T2,CCPG1,MS4A7,PLAA,QKI,SLC4A8,SMARCAL1,CPS1,SUSD5,SLITRK5,DOCK4,GAPVD1,ZFYVE16,CENPL,IST1,YTHDC1,DTNA,FCF1,PHF20L1,MBNL2,KMT5B,COPS4,ING4,CALCRL,CEP85L,ZNF461,ACSL4,TAOK3,GORAB,SUCO,SEC23B,ATP13A4,FLT1,TMEM107,SMC2,UFM1,KHDRBS3,CELF1,MEGF10,ERAP1,SULT1C4,GGTA1P,MSL3,ZNF782,RNF165,PSIP1,GUCY1B1,MAP4K5,DHX35,HSF2,KIF5A,STXBP5,HECTD2,NCOA7,MAP6,MARK1,MAT2A,MATN3,MBD1,MEF2C,MEIS1,BLOC1S2,ZNF92,MXI1,MYCN,NF1,VWA2,SMIM11A,NUCB2,DPY19L2P2,ABCB1,SNX10,RETREG1,PPP2R5E,PRKACB,EPDR1,MAPK9,PIGG,MTMR10,PTPRG,C1orf109,QDPR,FAM184A,ZNF493,REV3L,RFX3,KLHL11,YY1AP1,FBXW7,LRRK2,ABCA11P,ATAT1,SGK1,SEC31A,SLC6A11,SEPHS1,CCDC88A,SLC11A1,LGI3,TET1,SNRPN,BDP1,TEX2,LMO3,POGZ,LARP4,NXT2,MPRIP,KLHL7,TCF4,ZEB1,TRIM2,PCDHGB7,SYNE1,FRYL,SIK3,TEK,C18orf54,AP4E1,SLC44A1,LRRC8A,TRIO,DCBLD1,CCDC14,ZBTB14,MKRN3,FTSJ1,SMARCAD1,RNF103,MPPE1,KAT6A,HNRNPA3,NETO1" MicroRNA "CAGTATT,MIR-200B:MSigDB" "CAGTATT,MIR-200B:MSigDB" MSigDB 5.02E-54 2.81E-50 2.25E-53 2.07E-52 104 434 "MTUS1,ARHGAP20,TRMT9B,OGT,MAP4K3,VAT1L,ARHGDIA,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,ZMYM4,NOG,CFL2,NGEF,QKI,MAP4K4,CNN3,CNTFR,AKAP7,CSNK1G3,PHACTR3,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,SESN1,COPS8,FERMT2,PSIP1,HLF,NEGR1,AGFG1,KCND2,HECTD2,NCOA7,MAP2,LRP1B,MYCN,MYT1,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PKD1,KCTD15,PLCL1,SCHIP1,PPM1B,PPP2R2C,PRKACB,CEP41,PKIA,WBP1L,PTPN13,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC14A1,NAPB,SNAP25,TMCC1,FAM219A,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,VLDLR,SMARCAD1,EVI5,NAV3,PHTF2,FXR1" MicroRNA "CAGTATT,MIR-200C:MSigDB" "CAGTATT,MIR-200C:MSigDB" MSigDB 5.02E-54 2.81E-50 2.25E-53 2.07E-52 104 434 "MTUS1,ARHGAP20,TRMT9B,OGT,MAP4K3,VAT1L,ARHGDIA,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,ZMYM4,NOG,CFL2,NGEF,QKI,MAP4K4,CNN3,CNTFR,AKAP7,CSNK1G3,PHACTR3,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,SESN1,COPS8,FERMT2,PSIP1,HLF,NEGR1,AGFG1,KCND2,HECTD2,NCOA7,MAP2,LRP1B,MYCN,MYT1,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PKD1,KCTD15,PLCL1,SCHIP1,PPM1B,PPP2R2C,PRKACB,CEP41,PKIA,WBP1L,PTPN13,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC14A1,NAPB,SNAP25,TMCC1,FAM219A,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,VLDLR,SMARCAD1,EVI5,NAV3,PHTF2,FXR1" MicroRNA "CAGTATT,MIR-429:MSigDB" "CAGTATT,MIR-429:MSigDB" MSigDB 5.02E-54 2.81E-50 2.25E-53 2.07E-52 104 434 "MTUS1,ARHGAP20,TRMT9B,OGT,MAP4K3,VAT1L,ARHGDIA,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,ZMYM4,NOG,CFL2,NGEF,QKI,MAP4K4,CNN3,CNTFR,AKAP7,CSNK1G3,PHACTR3,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,SESN1,COPS8,FERMT2,PSIP1,HLF,NEGR1,AGFG1,KCND2,HECTD2,NCOA7,MAP2,LRP1B,MYCN,MYT1,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PKD1,KCTD15,PLCL1,SCHIP1,PPM1B,PPP2R2C,PRKACB,CEP41,PKIA,WBP1L,PTPN13,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC14A1,NAPB,SNAP25,TMCC1,FAM219A,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,VLDLR,SMARCAD1,EVI5,NAV3,PHTF2,FXR1" MicroRNA hsa-miR-124*:mirSVR_highEffct hsa-miR-124*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.21E-54 2.92E-50 2.34E-53 2.15E-52 157 1005 "FMNL2,PWWP2A,PTCHD1,TAOK1,OGT,DPP10,APC,SLC4A4,DPY19L3,TTLL9,CFLAR,PROM1,ARHGEF7,JAZF1,RAB29,DDR1,KALRN,PTBP2,SLC25A14,PRC1,CBS,CLDN10,P2RX6,LRBA,DCLK1,CDO1,CHN1,CHN2,NRXN3,PLAA,ABCG2,ARHGEF6,FAM149A,FAM171B,CRHBP,CS,OSBPL3,SIPA1L1,SLITRK5,USP6NL,HDAC9,GPRASP1,DGKB,DAPK1,ALKBH8,RHOBTB1,HS3ST2,CPEB2,DMTF1,DTNA,AASDH,PLEKHA1,PAN3,TUBD1,EPB41L2,RACK1,SUCO,HVCN1,ATP6V1H,CELF1,OGA,MEGF11,CHL1,C15orf41,GCNT2,ARFIP1,MMADHC,LYVE1,CRCP,DBF4,CBX1,RAB40B,ZNF782,STON1,DIDO1,ADAMTS6,IRAK3,VSIG4,HNMT,USP51,SOWAHA,ZIC5,RBPJ,SLC35G1,KCND2,KCNN2,LMO2,MAP4,MARK3,LRP1B,MSR1,NF1,NTRK2,OXTR,PCDH9,PDE4B,RETREG1,TRHDE,LRP12,ING3,PPP2R5E,RASGEF1B,SAMD9,PTK2,PID1,TMEM255A,SLC25A48,USP47,REV3L,GTDC1,RGS4,CARF,CCDC102B,TRAPPC13,ATXN2,SCP2,FUZ,CHD9,ST6GAL1,ANKRD6,DHX30,SLC12A2,LIMCH1,SNAP25,PDZD2,SP2,LARP4,ADHFE1,PRRC2C,ANKRD28,MMS19,MTCL1,FAM208A,ADGRL3,CUX2,ZEB1,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,ZFPM2,NR2E1,BEX4,STXBP4,DCBLD1,TSC1,SSBP2,HIRA,ZNF19,CELF4,ZXDA,ACTR3B" MicroRNA hsa-miR-433:mirSVR_highEffct hsa-miR-433:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.57E-54 3.68E-50 2.94E-53 2.71E-52 161 1056 "CLK4,XKR4,KLHL32,ADCY6,INTS2,HECW2,NME5,WDR35,C1QTNF3,USP37,ZBTB10,TMEM108,STX16,N4BP2L1,TTLL9,BARD1,MTMR2,RAB29,CHN2,MS4A7,TOGARAM2,CNRIP1,CPS1,CSNK1G3,SIPA1L1,GAPVD1,ARHGAP24,CENPL,ARMCX4,MYEF2,RHOBTB1,SACS,WDR20,RAB39B,DMD,DNM1,CDON,RCAN1,ARRDC4,WDPCP,RASGRP1,KCTD3,COPS4,STARD3NL,DCTN4,EPHB1,ENPP6,RABEPK,DENND4A,CDKL3,TLR7,EXTL2,EZH1,ABCA8,ZNF461,RPS6KC1,ACSL4,FDFT1,PRKAG2,COQ5,SMC2,ST6GALNAC3,GALC,DISC1,NEU3,PPARGC1A,RAB30,TOX3,POLL,RAB40B,FERMT2,GPD2,GPR12,GRIA2,PSIP1,AGBL5,HNMT,SMAP1,IL12A,LRRTM1,ITPKB,JAK2,KCNJ16,KIF2A,KPNA5,MAP4,LYPLAL1,MARK3,MSR1,MXI1,MYO9A,NF1,OCRL,GPR137C,PRTG,GPR85,PURG,PRKACB,MTMR10,ELOVL2,PTK2,TTC13,ZNF844,TMEM255A,RAP1GDS1,RET,GTDC1,MRPS18A,RIC8B,CCDC82,CARF,ROBO1,ROBO2,FBXW7,ABCA11P,CLIP1,ZNF354C,ZNF568,SATB1,CSRNP3,SCN8A,KIF16B,CHD9,SNRPN,PDZRN3,BDP1,ZNF302,KLHL7,VPS13A,ANKRD12,CAMTA1,FAM208A,ADGRL3,SATB2,ZEB1,TEK,PMS2CL,ITGB3BP,ARL10,MTMR14,TMPO,FAM124A,C9orf85,RUNDC3B,PPIL6,TSC1,RPL7L1,FAM155A,PLEKHH2,BCL2L13,VLDLR,ZNF781,TRIM9,LYPD6,POLR3H,EMSY,PARP11,MARCH8,CASC15,GAN,FAM198A" MicroRNA hsa-miR-362-3p:mirSVR_highEffct hsa-miR-362-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.84E-54 3.83E-50 3.06E-53 2.82E-52 135 750 "ADD2,AP2A2,HACE1,ADGRF5,PHF12,BCAS1,RGS20,EIF4G3,ATP1B3,BCL7A,BMPR1B,PTBP2,SPAG9,ARHGEF25,KRIT1,ZMYM4,SOCS6,PLAA,CLTB,ARHGEF6,COL9A3,IGDCC3,RBM39,CRMP1,RNF14,ABCG1,CSNK1G3,PDE4DIP,LONRF1,DAPK1,GOLT1B,EDNRA,PHF20L1,SUGP2,EIF4G1,CALCRL,EPHB1,FGF12,FGF14,SLC37A3,JKAMP,NBEA,POMT1,ST6GALNAC3,SARAF,RAPGEF6,DISC1,WASHC2A,USP19,MALT1,GLYR1,TNRC6A,MSL3,KDM2B,MAP7D2,DCLK2,BTN2A1,RNFT2,MAP4K5,TNFAIP8L3,HNF4G,SMAP1,IL6ST,GPR155,MARK1,POC1B,RTL5,NF1,NPY,NOVA1,P2RX7,PCSK5,PDE3A,PDE4D,OLA1,ZNF655,PLIN1,PRKACB,CEP41,SLC26A11,QRICH1,PTPRG,FAM184A,ZNF493,OXR1,ERI2,ZDHHC4,ZFHX4,CCDC102B,RPE,RPL15,LRFN5,SCN8A,FBXO11,NUBPL,SEPHS1,TET1,ZNF667,CMTR2,LARP4,ELOVL4,PRRC2C,SYN2,TACC1,TCEA1,ZEB1,DOCK9,PCDHB10,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TIAM1,HEY1,ERCC6L2,RGMB,UBE2H,PLEKHH2,CLDND1,PCDH20,ZBTB14,CIAPIN1,NAV3,RGS7BP,UBE3B,HNRNPA3,PHTF2,NHSL1,NETO2,FAM198A" MicroRNA hsa-miR-1972:mirSVR_highEffct hsa-miR-1972:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.87E-54 4.40E-50 3.52E-53 3.24E-52 136 762 "FMNL2,PWWP2A,AMPD2,LRCH2,LGR5,BCHE,SYNJ2,MTMR2,KYAT1,USP2,RAB33A,PPT2,LY86,CNN3,ARMC8,LETMD1,ABI3BP,CREM,CSNK1E,KATNAL2,IP6K1,YTHDC1,MYEF2,PLPPR4,USP3,DPP6,PDCD6IP,FAM78B,DNM1L,SNX29,WDPCP,EGFR,EGR3,ING4,STARD3NL,LRRC17,ETV1,STRADA,KAT8,MED12L,FGF11,POLK,GALNT15,FAM120B,ZNF274,KIAA1841,TUBGCP4,ARFIP1,GGT7,NTNG2,SERP2,COQ10A,RNFT2,GUCY1B1,LAMP2,STMN1,LIMS1,MAN2A2,MAP2,MBD1,TM6SF1,MEIS1,KCTD6,KITLG,COL28A1,NDP,PCBP3,NTRK2,PDE1C,PDE4D,PFKFB4,PLCL1,PPM1B,RASGEF1B,PRKACB,MASP1,BCAS3,CNTLN,PTH1R,PTPRB,PTPRO,ZCWPW1,RASGRF2,ZMAT4,GTDC1,RGS4,ELP2,BAALC,HSD11B1L,NCBP3,HKDC1,NUBPL,SLC6A11,SLC12A4,ATF7IP,RCOR3,SNRPN,MYO16,DOP1A,ZSWIM8,GLT8D1,MYCBP2,SS18,TTBK2,RGL1,SEPT3,PLCB1,C12orf76,TACR1,TAL1,FAM208A,PCDHB4,PCDHB3,FRYL,AP4E1,HEY1,CSMD1,SYNPO2,METTL3,MGAT5B,CCDC136,RICTOR,TRIM9,ZNF45,LYPD6,ZNF189,ZFAND5,EMSY,LINC02210,ADAMTS9,MDH1B,SLC17A7,SMIM8,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-595:mirSVR_highEffct hsa-miR-595:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-53 5.63E-50 4.49E-53 4.14E-52 138 786 "CLK4,ACTN1,PLEKHH1,BEND6,KIAA1324,CEP126,LCORL,MAP4K3,ZBTB10,BACH1,SYNJ1,KALRN,HIP1R,CCNH,USP6,RGN,TIGD7,CHN2,CNOT8,RAB28,NRXN3,TPP1,MAP4K4,BAG4,CREM,RGS6,PHACTR3,SLITRK5,PUM1,HDAC9,PITPNC1,HEPH,MYEF2,KIAA0753,GRIN3A,CPEB2,PDCD6IP,DNM1L,MBNL2,PLEKHA1,C8orf37,GPHN,CEP85L,ADGRV1,SH3YL1,ACSL4,TAOK3,GORAB,FER,FGF12,BAIAP2,SUCO,FOXF2,SYNCRIP,SEMA4D,PSD2,NOP56,NELFCD,PDLIM5,OGA,ERAP1,ZNF559,C15orf41,GHR,LYVE1,RAB30,WDFY3-AS2,GPR37,TMEM121B,DIDO1,HAS2,AGBL5,IGF1,MOV10,BLOC1S2,RTL5,NEK1,VWA2,DNHD1,IGSF11,GLIPR1L2,ETFRF1,PDE4D,GPR85,PDZRN4,MAPK10,ANKHD1,MTMR10,PTK2,ZIK1,PTX3,SLC25A48,FAM66C,RBBP6,GTDC1,ZDHHC4,ATP8B4,STK32B,TRAPPC13,HES6,SGK1,KIF21A,CPEB3,MYO18A,SYBU,BTBD3,ZNF430,ARHGEF40,CCDC88A,CPEB4,MBD5,SNRPN,DOK5,ATP10B,KLHL7,COBL,SATB2,CLASP1,FRYL,TEK,ITGB3BP,AKTIP,NPL,RUNDC3B,AMACR,CLHC1,UBTF,CLDND1,ZNF74,MKRN3,ZNF138,STOX2,PRDM10,MDH1B,NHSL1,IFT88,RNF146,SPATA13" MicroRNA "ACTGTGA,MIR-27A:MSigDB" "ACTGTGA,MIR-27A:MSigDB" MSigDB 1.24E-53 6.94E-50 5.53E-53 5.09E-52 105 447 "ADCY6,PLEKHH1,AK2,SEMA6A,PITPNM2,ANK2,APAF1,APBA2,CHRD,NCOA1,STX16,DPY19L3,NRP2,CA12,CAPN3,C1orf52,FOXN3,SOCS6,CLCN3,QKI,ARMC8,CABP1,ZNF385A,SLC35F1,HAPLN1,CSF1,RGS6,LONRF1,SPATA2,ELMO1,POM121,ARRDC4,E2F6,EDNRA,FAM13A,EGFR,MBNL2,EPB41,RCAN2,DNAJC27,EYA1,SUCO,RGPD5,PDLIM5,ST6GALNAC3,DOT1L,BRSK1,NEURL4,GABRB3,PCDH17,RUNDC3A,CIT,PTPRT,FAM222A,ZHX1,SOWAHA,LIFR,NCOA7,AQP11,MATN3,MEIS2,MSI1,MYT1,NFE2L2,NOVA1,NPTX2,ZNF827,CDK18,PDE3A,PDPK1,PPARA,PKIA,RELN,MTMR10,NKAIN1,FAM184A,ZFHX4,FBXW7,RXRA,SEMA6D,CASC3,PPM1E,CPEB3,CPEB4,SNAP25,TMCC1,SOX11,KDM3A,NFASC,TROVE2,NXT2,SEPT3,SYT1,CAMTA1,KLHL4,SATB2,RPGRIP1L,TSC1,FLRT2,PLEKHH2,MICU3,EVI5,JMJD1C,ADAMTS10,NETO1" MicroRNA "ACTGTGA,MIR-27B:MSigDB" "ACTGTGA,MIR-27B:MSigDB" MSigDB 1.24E-53 6.94E-50 5.53E-53 5.09E-52 105 447 "ADCY6,PLEKHH1,AK2,SEMA6A,PITPNM2,ANK2,APAF1,APBA2,CHRD,NCOA1,STX16,DPY19L3,NRP2,CA12,CAPN3,C1orf52,FOXN3,SOCS6,CLCN3,QKI,ARMC8,CABP1,ZNF385A,SLC35F1,HAPLN1,CSF1,RGS6,LONRF1,SPATA2,ELMO1,POM121,ARRDC4,E2F6,EDNRA,FAM13A,EGFR,MBNL2,EPB41,RCAN2,DNAJC27,EYA1,SUCO,RGPD5,PDLIM5,ST6GALNAC3,DOT1L,BRSK1,NEURL4,GABRB3,PCDH17,RUNDC3A,CIT,PTPRT,FAM222A,ZHX1,SOWAHA,LIFR,NCOA7,AQP11,MATN3,MEIS2,MSI1,MYT1,NFE2L2,NOVA1,NPTX2,ZNF827,CDK18,PDE3A,PDPK1,PPARA,PKIA,RELN,MTMR10,NKAIN1,FAM184A,ZFHX4,FBXW7,RXRA,SEMA6D,CASC3,PPM1E,CPEB3,CPEB4,SNAP25,TMCC1,SOX11,KDM3A,NFASC,TROVE2,NXT2,SEPT3,SYT1,CAMTA1,KLHL4,SATB2,RPGRIP1L,TSC1,FLRT2,PLEKHH2,MICU3,EVI5,JMJD1C,ADAMTS10,NETO1" MicroRNA hsa-miR-183-5p.2:TargetScan hsa-miR-183-5p.2 TargetScan 1.95E-53 1.09E-49 8.68E-53 7.99E-52 117 565 "KLHL32,ADCY6,PTCHD1,KCTD16,OSBPL8,ALK,OGT,LRCH2,PKP4,CDK13,PDE8B,DPY19L3,ADAM23,MTMR3,JAZF1,LDLRAD4,CACNB4,LDB2,DGKI,EVI5L,L3MBTL4,DLGAP2,CACNA2D2,MAP4K4,MYRIP,CDC42BPB,PREPL,LRIG1,RIMS4,CNTNAP2,PPP1R16B,ERC2,APPL1,ARHGAP24,RASSF2,IST1,SACS,E2F5,FEM1B,PHF20L1,EIF5,GPHN,FHL1,PCYOX1,FAM49B,ATP2C1,FYN,B4GALNT1,PCDH17,RAB30,AIFM3,KDM2B,GPR12,PCLO,PARD3B,KAT7,RASSF8,FRMD5,BACH2,CDH20,KCNN3,LAMP2,HECTD2,LSAMP,MAP2,MBNL1,CHIC1,MEF2C,MID1,PPM1L,MITF,NOVA1,NOVA2,NPTX2,IGSF11,P2RY1,PIK3C2A,PIK3R1,FAM216A,PLTP,EPB41L4B,CNNM2,APTX,PTPRD,RFX3,PRIMA1,CYB561D1,ROBO1,MCMBP,SATB1,MRAS,PPM1E,FNDC3A,BTBD3,ELMO2,CPEB4,ARHGAP26,NFASC,LMO3,DIP2A,KLHL7,COBL,ANKRD28,FBXW11,GPRIN3,AP4E1,CBX5,LRRC8A,RUNDC3B,RICTOR,CADM2,NAV3,JMJD1C,IFT88,NETO2,GAN,PRRT4" MicroRNA hsa-miR-655-3p:TargetScan hsa-miR-655-3p TargetScan 2.01E-53 1.13E-49 8.95E-53 8.24E-52 121 606 "ADCY5,CCDC85A,ADD1,ESYT2,AP2A1,HECW2,CASKIN1,PCDH19,MARCH4,LRCH2,ANK2,APBB2,APC,EPB41L5,GAS7,NCOA1,ATP2A2,KSR1,CALM1,RUNX1T1,CDH2,DCLK1,NUMBL,CHN2,CNR1,HAPLN1,PLCXD3,HDAC9,MATR3,PITPNC1,JAKMIP2,DMD,CPEB2,RCAN1,EBF1,HIPK3,OPTN,C8orf37,EPB41,EPB41L2,MTSS1L,DENND4A,ETV1,PCYOX1,APOPT1,CHL1,GPR162,AHDC1,GFRA2,FERMT2,GPD2,FAM19A2,PSIP1,RASSF8,HMGCR,AGFG1,RBPJ,IPO5,KTN1,LSAMP,MAP4,AQP11,LRP1B,MEIS1,MID1,MITF,MMP16,MYO9A,NF1,NFYA,NOVA2,OPA1,PAX6,PDE4A,PIK3C2A,PIK3R1,FAM216A,CEP41,DIRAS2,ANKHD1,ELOVL2,PTPRG,PTX3,RBBP6,KHDRBS2,RDX,GTDC1,RFX3,SATB1,CSRNP3,FNIP1,CPEB3,MBD5,PEG10,CDK19,CLSTN2,NKAIN2,MPRIP,PRRC2C,ANKRD28,CAMTA1,ATMIN,SATB2,DOCK9,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CBX5,LRRC8A,CSMD1,NR2C2,REEP1,DPYSL5,ANKS1B,CADM2,RGS7BP" MicroRNA hsa-miR-34a:mirSVR_highEffct hsa-miR-34a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.12E-53 1.19E-49 9.44E-53 8.70E-52 141 825 "SYS1,KDM5D,ADCY6,ADD2,ADRA1D,MTUS1,HACE1,KIAA1324,ALCAM,DOC2A,ANK2,PKP4,VAT1L,TMEFF1,NCOA1,DPY19L3,ADAM23,BCS1L,DST,SYNJ2,ARHGEF7,JAZF1,WASF1,CALB1,KALRN,CERS5,DGKI,ZMYM4,EVI5L,TIGD7,NUMBL,EPS15L1,RAB33A,SULT4A1,HECTD1,AKAP6,MYRIP,PREPL,CLIP3,TRIM69,CS,LRIG1,CNTNAP2,ERC2,PNPLA8,IST1,DGKB,BRINP1,GIT2,ELMSAN1,RCAN1,DNM1L,E2F5,FAM13A,KMT5B,RGS17,TMEM35A,C8orf37,SPEG,SIRPB1,NRN1,ACSL4,SUCO,SCARA3,HPCAL4,PSD2,SLC37A3,NOP56,HVCN1,GABRA3,GHDC,TUBGCP4,TUBA8,MSTN,LOXL3,GNAO1,CCDC184,PCLO,NXPH3,ARHGAP36,GABARAPL2,ITPKB,KCNK3,KIT,HECTD2,CLEC18A,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,CDK18,GPR85,GNG2,JAKMIP1,PURG,STRN3,ING3,PKIA,CNTLN,MTMR10,PTPRD,EML5,PTX3,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RIC8B,RNASEL,ZFHX4,SATB1,ATXN7,KDM4D,DMRTC1,KIF13A,SNRPN,PDZRN3,POGZ,ZC3H4,ARHGEF9,SYT1,CAMTA1,FAM208A,ATMIN,SATB2,DOCK9,USP32P1,RNF216P1,ITGB3BP,TSN,PLEKHH2,BCL2L13,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-53 1.33E-49 1.06E-52 9.71E-52 190 1446 "FMNL2,ADCY6,ESYT2,OSBPL8,CC2D2A,AK2,HFM1,UNC79,C6orf89,MYH7B,EPB41L5,LGR5,CDC14B,PLA2G4C,CCAR2,ADAM15,HCN2,LDLRAD4,CA12,CABP7,CAST,CD86,ARHGEF1,CDH2,CDO1,CRLF1,PLEKHB1,ARHGAP22,LHX2,TPP1,QKI,TMEM184B,CNN3,IQCK,CABP1,FAM171B,CLOCK,GDA,LRIG1,IPCEF1,RIPOR2,KIF26A,RASSF2,MAML1,DAPK1,AIF1L,GIT2,DBT,ARMCX2,CHRDL1,CDON,RCAN1,GOLT1B,E2F5,E2F6,EDN1,PHC2,HIPK3,FCF1,GOLGA7,PLEKHA1,CALCRL,MFSD10,STX2,ERBB2,ZNF549,GMPR2,RACK1,FECH,FGF1,FGFR1,MAD2L2,FOXF2,ZBED3,DISC1,SEPT9,ARFIP1,LYVE1,SPIN1,GRIA2,GSN,FAM19A2,KAT7,BVES,ATOH8,IRAK3,FRMD3,ATXN2L,ELOVL5,IFI16,RBPJ,IL6R,ZNF678,SLC35G1,L1CAM,LAMP2,ASPRV1,MBNL1,CHST6,SHC3,MIA2,POC1B,MKLN1,AFDN,MOV10,DBNL,COMMD5,MYCN,NBL1,NCF2,NFIX,NME4,PIK3C2A,ZNF655,RETREG1,PLEC,SMOX,PPARA,MINDY2,PRKCB,EPDR1,PRPH,CNNM2,LAMA1,TMEM104,SPDL1,PTPRB,USP47,ZDHHC14,DPF2,MORC4,RFX2,RGS4,KIF7,SLC25A36,ELP2,CCDC102B,SPIN3,RYR3,CASC3,SGK1,KIF16B,SHMT2,HKDC1,DZIP1,LIMCH1,KIF13A,ZHX3,UNC5B,TROVE2,ITPRID2,SAMSN1,MPRIP,KANK1,SYPL1,MTCL1,CAMTA1,DNMBP,IQCE,NEU4,KIAA0930,CUX2,TPCN2,SYNE1,SIRT1,TMEM121,GPR161,SLC44A1,ICAM5,TPM1,C9orf85,PDSS1,TRPS1,TSN,MTCH1,WIPF1,CLDND1,ANKS1B,FTSJ1,DHX33,ZXDA,EVI5,TUBA1A,PLSCR4,MSRB3,TTC7A,FXR1,FRMD6,GAN,LAS1L" MicroRNA hsa-miR-2278:mirSVR_highEffct hsa-miR-2278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.83E-53 1.59E-49 1.26E-52 1.16E-51 158 1030 "AXIN2,KIAA1211,ALCAM,BBOX1,OGT,EP400,APC,NT5C3B,LINC00173,ZBTB10,NCOA1,ADAM23,BBS2,CFLAR,FUBP1,SCAPER,JAZF1,CACNA1G,CA8,THSD7A,KALRN,PTBP2,CERS5,LRRFIP1,SLC4A8,ZFP28,SNCAIP,CSF1,RGS6,CSNK1E,PDE4DIP,FAM169A,FAM131B,CCDC144A,GAPVD1,CENPL,ZNF337,LONRF1,KCTD8,MYEF2,CHRDL1,EXOG,HS3ST2,DTNB,RASA4,RABEPK,TAOK3,FGF11,FHL1,POLK,SYNCRIP,RGPD5,PSD2,APOPT1,PDLIM5,ST6GALNAC3,GAD1,DISC1,GATM,TCERG1,SPIN1,DCLK2,PRRC2B,PCLO,STMN2,GRIA2,ZNF496,ATXN2L,HLF,MSL1,RBPJ,INPP5B,INSM1,KCND1,KCNH2,KIT,SMAD1,MAP2,LYPLAL1,MARK3,MIA2,AFDN,ADAM22,THYN1,NDP,NF1,SMIM11A,NUCB2,PAX6,KCTD15,PLIN1,RANBP3L,PRKACB,PSD,BCAS3,PIGG,CNTLN,PTPRE,CEP97,RET,FIGN,ZFHX4,C12orf49,ROBO2,ABCA11P,RYR3,TRAPPC13,SATB1,SCN8A,PRCD,SEC14L1,COPZ1,PPM1E,FRMPD1,SLC11A1,KBTBD4,CPEB4,RBM34,DOP1A,TRERF1,DOK5,TEX2,PEG10,ZC3H13,NFASC,ZC4H2,ADHFE1,SYNE2,ARHGEF9,SYN2,SYT1,ANKRD28,MTCL1,MCF2L,PDLIM2,ADGRL3,AGTPBP1,ZEB1,SLC19A3,SIK3,CYB561A3,TEK,AP4E1,BHLHB9,SMUG1,STXBP4,DCBLD1,RUSC1,KCNE5,SSBP2,SLC47A2,ZNF24,ZNF540,CELF4,FTSJ1,WNK3,PLSCR4,PHTF2" MicroRNA hsa-miR-4318:mirSVR_highEffct hsa-miR-4318:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-53 1.63E-49 1.29E-52 1.19E-51 128 682 "CLK4,AS3MT,XKR4,CASKIN1,HACE1,TAOK1,FGD2,LCORL,ZNF582,ADAM23,RGS9,ST3GAL5,IL33,CLDN10,B4GALT6,PPT2,CCDC151,FHL5,CNR1,CNTFR,CREM,CRMP1,CTH,ARHGAP32,GAPVD1,DCAF8,PABPC5,ARMCX4,PITPNC1,CPEB2,DMTF1,DTNA,EDNRB,KLHL5,OPTN,SUGP2,PLEKHA1,EPB41,SRRM1,NRN1,STRADA,SLC9B2,FGF12,WDR83,AP4B1,GABRB3,ZNF274,DISC1,TUBA8,WASHC2A,TOX3,ZNF638,CIT,AP4S1,RBPJ,JAK2,LIMS1,HECTD2,MAP4,MEIS1,MN1,ADAM22,MYT1,P2RX7,P2RY1,PCDH8,PCDH9,GPR85,PIK3R1,PPARA,CEP41,MAPK7,HYDIN,RELN,SNRK,WDR25,RAD51D,ENOX1,REV3L,ERI2,DCUN1D2,CARF,ELP2,RPL15,ARMH4,ATAT1,SEC31A,SLA,NBPF1,SLC12A2,ATF7IP,ZKSCAN3,CDK5RAP2,MYH15,SNAP25,MBD5,MYO16,KDM4C,SAMSN1,ZC4H2,STAU1,ARHGEF9,SYT1,ANKRD12,MTCL1,FAM208A,ZFP90,ZEB1,TRIM2,USP32P1,GPRIN3,FRYL,SIK3,CYB561A3,AP4E1,ASXL3,CSMD1,SSBP2,UBE3A,ZIC1,ZNF19,AGMO,ANKS1B,CADM2,STOX2,PRDM10,TRAM2-AS1,RNF170" MicroRNA hsa-miR-218-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.10E-53 1.74E-49 1.38E-52 1.27E-51 140 816 "ACTN1,AP2A2,ZNF608,KLHL13,HFM1,LTBP4,ZFAT,CDC42BPA,PKP4,APC,SHROOM2,CCDC74A,EIF4G3,KSR1,DST,FUBP1,SCAPER,MTMR3,SPAG9,CDH2,LRRFIP1,SLIT2,SUMF2,RCHY1,LRIG1,VCAN,CNTNAP2,PNPLA8,DCAF8,EARS2,INTS1,IST1,DAPK1,SCRN1,GIT2,ELMSAN1,ZBTB24,FBXL5,POM121,SACS,SEC16A,DMTF1,PHC2,EEF1D,EGFR,MBNL2,RASA4,EIF4G1,KATNAL1,FAM198B,FOXO3,SEMA4D,ANKFY1,ATP6V1H,SRRM4,CSDC2,RNPS1,GLI2,RAB30,CBX1,FERMT2,ZNF496,EID2B,MSL1,SHISAL1,RBPJ,KIT,IPO5,HECTD2,MBNL1,MEIS2,MID1,MITF,MMP16,DNHD1,SLC11A2,KSR2,ZNF827,PKM,SH3KBP1,PPP2R5E,PRKAR1B,CNNM2,QRICH1,PTCH1,MTMR10,PTPRG,RIPOR1,USP47,SUSD4,RET,REV3L,UBR7,MRPS18A,SLC25A36,ROBO1,RPL15,GLDN,ZNF354C,SATB1,FNIP1,PUF60,ST6GAL1,SEC31A,SEPHS1,BTBD7,EPC1,COA1,UNC5B,ZC3H13,SS18,MPRIP,STAU1,SULF2,ZC3H4,PRRC2C,CAMTA1,SATB2,USP22,DOCK9,NSD1,PUM2,DICER1,PARD3,CHST5,TRPS1,UBE2H,UCHL1,CLIP2,RICTOR,ZNF711,SPIRE1,TFIP11,SLC38A1,HPS4,ITM2C,HNRNPA3,RNF170,NHSL1,AAAS" MicroRNA hsa-miR-105:PITA hsa-miR-105:PITA_TOP PITA 3.44E-53 1.92E-49 1.52E-52 1.40E-51 103 433 "RALGAPA1,USP31,HECW2,DPP10,EP400,MAP4K3,ZBTB10,NCOA1,SCAPER,CAMK2G,CLDN10,LDB2,CDH2,ZMYM4,CFL2,SRSF11,CNN3,CNR1,NCOR2,CSNK1G3,SOCS5,SLITRK5,RHOBTB1,YAF2,MBNL2,EIF4G2,COPS4,PAN3,ERBB4,ETV1,EXTL2,AMOTL2,SYNCRIP,NBEA,CELF1,OGA,GABRB3,TCERG1,COPS8,SPIN1,TNRC6A,POLL,PCLO,GRIA2,BACH2,MIER3,HLF,GABARAPL2,IGF1,MAP2,MARK1,MEF2C,MITF,MXI1,TCEAL5,NNAT,CNOT4,PCDH9,PDE4D,PDE1B,GPR85,GNG2,PPP3CA,PRKAB2,MTMR10,PTPRE,PTPRG,OXR1,ZFHX4,ZNF532,MRAP2,CLIP1,TRA2B,FNDC3A,FAM214B,CCDC88A,SLC12A2,CPEB4,CXXC4,SNAP25,FAIM2,FAM126B,SOX11,SP4,TEX2,PEG10,NKAIN2,ELOVL4,ARHGEF9,SYT1,CAMTA1,TCF4,SATB2,DICER1,ZFPM2,RIMBP2,R3HDM1,TRPS1,UBE3A,FLRT2,PRDM8,HNRNPA3,SENP7" MicroRNA hsa-miR-18b*:mirSVR_lowEffct hsa-miR-18b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.65E-53 2.04E-49 1.62E-52 1.49E-51 132 727 "XKR4,PWWP2A,ADRB2,CC2D2A,ZNF578,ARHGAP20,MARCH4,PARG,APC,SHROOM2,CDK13,NUMB,EIF4G3,ATP1B3,N4BP2L1,ADAM15,IL33,CAST,ISPD,SPAG9,CDC25B,SRSF11,NRXN3,COL11A2,SLC4A8,MYRIP,SEC24C,CSNK1E,SIPA1L1,SLITRK5,PLCXD3,LIN54,ELMSAN1,TIAM2,PARD6A,DLX1,DMD,TMTC1,PHF20L1,IRAK4,USPL1,EPB41,EYA1,FCGR1A,IQCG,EVL,SMC2,STAMBP,ZNF605,GABRG1,B4GALNT1,IP6K3,ERAP1,MTHFD2,LRRC37A6P,WASHC2A,SPIN1,ZNF638,PRUNE2,PLPP7,ZNF496,GUCY1B1,ATOH8,PADI2,NCKAP1L,ELOVL5,ZDHHC15,FAM95B1,RBPJ,SLC6A17,ITGAM,STXBP5,PAXBP1,MEF2C,MMP16,MYO9A,SFR1,PCBP3,CNTN3,PIK3R1,XRN1,PKM,PPP2R5E,HYDIN,ANKHD1,PTPRB,PEX2,MARCH1,RBBP6,RNASE1,PNMA8A,CCDC102B,RMI1,STUM,ZFP30,KIF21A,SHMT2,FHOD3,PPP4R3A,EPN2,KANSL3,BTBD7,ZNF667,ZC4H2,SEPT8,ARHGEF9,VPS13A,NUDT10,ANKRD28,FAM208A,DMXL2,DOCK9,AP4E1,ZNF106,CSMD1,ZNF346,SYNPO2,PPIL6,TTTY15,RPRM,CLIP2,XPO1,XRCC4,ZNF711,ZNF32,ZNF184,DHX33,EVI5,STOX2,MPPE1,WNK2,PHTF2" MicroRNA hsa-miR-342-5p:mirSVR_lowEffct hsa-miR-342-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.17E-53 2.89E-49 2.29E-52 2.11E-51 159 1047 "ASPHD1,CLK4,GALNT13,KIAA1211,AP2A2,SPOP,PITPNM2,AMPD3,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PPFIA3,ARNTL,ALDH7A1,N4BP2L1,ATP6V0A1,ADAM15,RGS9,ARHGEF7,CACNA1I,CFAP410,CA12,CACNA1B,KALRN,CAST,P2RX6,ENTPD6,DGKI,ZMYM4,EVI5L,CRLF1,NUMBL,ASIC3,ARMC8,COL11A2,CLIP3,RGS6,LRRC3B,OSBPL3,FAM169A,SLITRK5,CTH,PPP6R2,RUBCN,GAPVD1,RASSF2,GIT2,PITPNC1,JAKMIP2,DMPK,MED12,SEZ6L2,EGFR,RASA4,ING4,TNK2,RASGRP2,RABEPK,APC2,NRN1,CLVS1,RACK1,ZMYND10,STRADA,KAT8,FECH,FGF14,NELFCD,DLL3,DOT1L,B4GALNT1,ERAP1,CPLX2,ALDH1L1,GGT7,RNPS1,GNG4,SERP2,GSTM5,RABL2A,GUCY1B1,ATOH8,PADI2,AGBL5,CPT1C,CELF5,SMAP1,FAM95B1,GATD1,KIT,L1CAM,TTYH2,MBNL1,MYO6,FXYD7,NPTX2,OGG1,DPY19L2P2,ETFRF1,ZDHHC8,NLGN3,MAPKAP1,SEPT4,EPB41L4B,MAPK4,WBP1L,CASTOR1,ACSM5,ZSCAN2,TMEM231,SH3TC2,IQSEC3,GTDC1,RFX2,RIC8B,ROBO2,STK32B,FERMT1,AMBRA1,FAM214B,SLC11A1,MAST1,FAIM2,SNRPN,KDM4B,ZSWIM8,NMNAT2,ERC1,CDK19,MCF2L2,LMO3,PBLD,DIP2A,STAC2,KANK1,KLHL7,SYP,COBL,MCF2L,CUX2,SZT2,SYNE1,FRYL,HIF3A,CDH22,R3HDM1,KAT6B,RASD2,SYNPO2,AMACR,BCL2L13,VAV1,DPYSL5,SH3GLB2,NT5M,PRDM8,PCBP4,PARP11,DOCK8,ST8SIA2" MicroRNA hsa-miR-376a*:mirSVR_highEffct hsa-miR-376a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.63E-53 3.15E-49 2.49E-52 2.29E-51 154 986 "GALNT13,RNF150,MTUS1,TXNDC16,SPARCL1,DPP10,PPP4R4,IGDCC4,SPTBN4,MARK4,NUMB,N4BP2L1,MPDZ,SGCE,CACNA1G,KALRN,PTBP2,CAST,KRIT1,DGKI,LRBA,LRRFIP1,NRXN3,PLAA,TMEM184B,MAP4K4,AKAP6,ABI3BP,SUSD5,PHF14,CTH,KIAA0586,RHOBTB1,SACS,WDR20,USP3,DMTF1,DTNA,ABCC5,HIPK3,FRY,YAF2,PHF20L1,TENM1,RABEPK,DENND4A,FER,FGFR1,SEC23B,UFM1,TPK1,ZNF605,CELF1,STAU2,MEGF11,MEGF10,HRASLS5,B4GALNT1,PPARGC1A,DBF4,SPIN1,KIAA1958,ADGRA3,PRUNE2,STON1,ATE1,PSIP1,GUCY1B1,TNFAIP8L3,ELOVL5,CFAP126,HSPA1L,RBPJ,KPNA5,MAP6,LYPLAL1,AQP11,MEIS1,MIA2,MSR1,NDP,NINJ2,NRCAM,SLC10A4,GPR85,OLA1,PIK3C2A,ZNF655,ING3,HYDIN,PTN,ZIK1,PTPRH,RASGRF1,RDX,PBRM1,SUGCT,CARF,GSTCD,CCDC102B,RPE,NEK11,BAALC,ATP8B4,CLIP1,ZNF568,LRFN5,FNIP1,KIF16B,CPEB3,SHC4,CHD9,CNKSR2,FAM81A,SEPHS1,SLC9A5,TET1,ANKRD36,MBD5,FNBP1,SP4,KDM4C,SPART,CAMTA2,DIP2A,SULF2,VPS13A,TACC1,MTCL1,ADGRL3,ZEB1,RPGRIP1L,TCF12,SYNE1,PCDHB7,PUM2,SIRT1,AP4E1,TIAM1,BEX4,NPL,RPL7L1,UGT8,ZNF711,ZNF28,ANKS1B,FIP1L1,EPM2A,RGS7BP,AMN1,RTN4,PHTF2,TTC7A,GAN" MicroRNA hsa-miR-18a:mirSVR_highEffct hsa-miR-18a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.02E-53 3.37E-49 2.66E-52 2.45E-51 131 719 "KCNH8,AS3MT,XKR4,TMCC3,PLEKHH1,PWWP2A,BEND6,ALCAM,BBOX1,OGT,MAP4K3,VAT1L,NCOA1,ATP1B3,NAE1,CA8,CA12,ZNF501,USP6,SYNGR3,LRBA,LRRFIP1,QKI,AKAP7,TBPL1,AHCTF1,SLC35F1,CPS1,RNF14,CLIP3,RGS6,SIPA1L1,SOCS5,DZIP3,GREB1,RIMS2,DCAF4,DOCK4,HDAC9,LIN54,MATR3,DBI,PITPNC1,TMCC2,SEC16A,DTNB,PHF20L1,VPS13B,TLR7,DLC1,CEP78,MED12L,FGF1,FGF12,SUCO,KHDRBS3,STAU2,OGA,SULT1C4,PPARGC1A,STARD3,HLF,HNMT,ZNF491,ZDHHC15,TCEAL6,HSF2,SOWAHA,MBNL1,OCRL,PCSK1,PDE4D,PDE1B,GPR173,PIK3C2A,ZNF655,EXOSC10,SH3KBP1,PRKACB,MAPK4,HYDIN,DIRAS2,MASP1,VPS13C,SNRK,IQSEC3,NWD1,RBBP6,RBBP8,FIGN,RNASEL,TRAPPC13,SATB1,CSRNP3,COPZ1,ZFP30,BTBD3,SLC6A11,SMARCC2,DOP1A,PDZD2,KDM3A,KDM4C,TEX2,CDK19,TSPYL2,SPART,NKAIN2,NXT2,CEP68,VPS13A,TMEM150C,ANKRD28,C12orf76,ZFP90,FRYL,SIK3,TEK,R3HDM1,NPL,PLEKHH2,WIPF1,ZBTB14,TRIM9,CELF4,EMSY,CADM2,STOX2,ADAMTS9,ITM2C,EPM2A" MicroRNA hsa-miR-584:mirSVR_highEffct hsa-miR-584:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.84E-53 3.83E-49 3.02E-52 2.78E-51 151 951 "FMNL2,KIAA1211,KLHL13,HACE1,KIAA1324,OSBPL6,SRPX,CADPS,ATP1B3,ZNF583,N4BP2L1,SEC11C,IL33,CALB1,CALB2,CH25H,RUNX1T1,CD38,SOCS6,CHN1,C4orf33,AKAP6,MYRIP,ZNF521,AKAP12,HAPLN1,HINFP,NCOR1,VCAN,PUM1,USP6NL,GAPVD1,DGKB,ARMCX4,LYPD1,POM121,PLPPR4,SPOCK3,GRIN3A,USP3,NR1D2,DMTF1,FAM78B,E2F5,FCF1,PHF20L1,CALCRL,DCTN4,RABEPK,NSRP1,FAM198B,TAOK3,CHST15,GTF2IRD2,MEX3B,ATP13A4,STAMBP,ATP6V1H,HRASLS5,GALNT15,GABRG2,KIAA1841,ZNF276,SPIN1,GLI2,MSL3,MAP7D2,FERMT2,WDFY3-AS2,FAM19A2,HNMT,HSF2,SLC35G1,KCND2,KCNN3,KIF2A,IPO5,MAP2,LYPLAL1,AQP11,MATN3,MEIS2,KCTD6,SCAMP5,MITF,MSR1,ZNF92,MXI1,NF1,NPTX1,PCDH9,SLC10A4,OLA1,ZNF655,SNX10,PCDH18,EXOSC10,CYBC1,PTPRB,TTC13,TUG1,CCDC40,SH3TC2,SUSD4,REV3L,RFX3,SLC25A36,CCDC82,SETD5,TMLHE,CARF,RORB,CCDC102B,RPE,FBXW7,ATP8B4,KCNIP3,ZNF354C,ZNF568,SUPT20H,CNKSR2,NUBPL,CCDC88A,SLC12A2,ANKRD36,INAVA,ZNF415,HECW1,SPART,POGZ,ITPRID2,SSTR2,LARP4,VPS13A,SYPL1,FBXW11,ZEB1,ERCC6L2,C9orf85,PPIL6,TBC1D15,ZBTB14,ZIC1,FSTL5,EML6,ANKS1B,SIGLEC10,EPM2A,RGS7BP,SMIM8,FBXO36" MicroRNA hsa-miR-500b:mirSVR_highEffct hsa-miR-500b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.17E-53 4.57E-49 3.60E-52 3.32E-51 122 624 "ACADM,SYS1,ATP1B3,ADAM23,LINC00847,CFLAR,CASTOR3,CALB2,CAMK2B,CAST,USP6,LRBA,CLGN,COPB2,NRXN3,TPP1,AKAP6,RBM39,RNF14,UBXN2A,ZFYVE16,KIAA0586,PITPNC1,KIAA0753,DNM1,USP3,CASP8AP2,ACOT8,PDCD6IP,WDPCP,KLHL5,APH1A,CEP85L,ADGRV1,F8,CORO2B,SEC23B,ZNF605,RAPGEF6,C15orf41,ADAM28,TXNL4A,COPS8,DBF4,KDM2B,KCNMB4,GSTT2,RASSF8,MIER3,HNMT,USP51,SMAP1,IGF1,SCIN,JAK2,SLC35G1,KCNH2,IPO5,HECTD2,MMP16,ADAM22,CNOT4,PCSK5,PDCD2,PLCD1,JAKMIP1,PRIMPOL,STRN3,PILRA,PPM1B,PRKACB,EPDR1,HYDIN,CNTLN,BDNF-AS,TMEM260,PTPRD,PTPRE,CEP97,REV3L,SLC25A36,SETD5,ARMC5,CCDC102B,RPE,BAALC,ATAT1,RMI1,SATB1,CASC3,ST6GAL1,SEPHS1,ANKRD36,MBD5,ZNF415,SNRPN,KDM4B,USP33,NKAIN2,STXBP1,NUDT10,TACR1,MTCL1,ATMIN,TCEA1,FRYL,C18orf54,TLR4,ERCC6L2,CDK20,RUNDC3B,TUBB1,UGT8,ZNF709,PCDH20,MICU3,KCNT2,LYPD6,CELF4,SLC17A7,FBXO36,ADAMTSL3" MicroRNA hsa-miR-548d-3p:PITA hsa-miR-548d-3p:PITA_TOP PITA 8.39E-53 4.69E-49 3.69E-52 3.40E-51 131 721 "KCNH8,FMNL2,AXIN2,MARCH4,UNC79,PDZD4,PITPNM2,AMPH,CDC42BPA,APC,USP37,SEMA4G,ZBTB10,ATP1A1,STX16,RNF182,RUNX1T1,CDH2,CFL2,FOXN3,NRXN3,COL4A5,CDC42BPB,CSNK1G3,SOCS5,DCAF8,KCTD8,MYEF2,SNAP91,MTX3,FAM107B,GRIN3A,DMD,CPEB2,DMTF1,DPYSL2,YAF2,KMT5B,EIF4G2,PAN3,EIF1,EPB41,RCAN2,ACSL4,SUCO,EVL,NBEA,IQGAP2,SRCAP,ARFIP1,PCDH17,TCERG1,SPIN1,TNRC6A,PRRC2B,GRIA2,PSIP1,MAP4K5,PACSIN2,FRMD3,BACH2,HLF,NEGR1,SMAP1,RBPJ,IPO5,KTN1,MARK1,MITF,MSI1,ZC3H12B,NEK1,NFIX,PCDH9,GPR85,NLGN3,PURG,STRN3,EPB41L4B,PPP3CA,KANSL1,SNRK,PTPRD,NKAIN1,PID1,RAP1GDS1,PBRM1,ZNF532,CARF,ZC3H14,LRRK2,RTN1,SALL1,SEMA6D,TRA2B,SGK1,CPEB3,CHD9,NLGN1,ST8SIA1,BTBD3,CCDC88A,CPEB4,TMCC1,TEX2,CDK19,POGZ,LARP4,ERBIN,NSFL1C,PLCB1,ANKRD28,CAMTA1,TBL1X,DMXL2,RPGRIP1L,DOCK9,R3HDM1,TSC1,UBE2H,UBE3A,USP1,PCDH20,ZFAND5,CADM2,WNK3,PARP11,PDSS2,RGS7BP,KAT6A,HNRNPA3" MicroRNA hsa-miR-9:PITA hsa-miR-9:PITA_TOP PITA 1.02E-52 5.71E-49 4.49E-52 4.14E-51 119 594 "ASIC1,GALNT16,ESYT2,PTCHD1,HECW2,ALCAM,PITPNM2,PARG,SHROOM2,CDC14B,NCOA1,CCAR2,SYNJ1,MTMR2,CALB2,KALRN,PTBP2,LRBA,ARHGEF2,MAGI1,DLGAP2,FAM19A5,QKI,CNTFR,COL9A1,TBPL1,BAG4,CLOCK,NCOR2,SOCS5,ARHGAP24,DGKB,ARMCX2,JAKMIP2,RHOBTB1,SACS,MTX3,FAM107B,CPEB2,PDCD6IP,CNNM1,TMTC1,FRY,EGR3,TENM1,FGF12,FOXO3,GAD1,MTHFD2,SRCAP,PCDH17,LYVE1,TNRC6A,PCLO,PTPRT,ADAMTS6,HAS2,MIER3,ACOT7,AGFG1,ZIC5,IL12A,TTYH2,NCOA7,MBNL1,ADAM11,KITLG,MKLN1,NEK1,NPTX1,GPR137C,CNTN3,PRTG,GPR85,PIK3C2A,CCSER2,XRN1,CNNM2,SNRK,SLC25A36,PBRM1,MCMBP,SGSM1,HUNK,SCN2B,FNIP1,TRA2B,KIF21A,CPEB3,AMBRA1,FAM81A,SLC8A1,CCDC88A,CPEB4,OGDHL,TMCC1,SPART,NFASC,ERBIN,ELOVL4,STX1A,ANKRD12,TRIM2,DOCK9,FRYL,DICER1,SIRT1,AP4E1,NR2E1,TRIM9,TCEAL7,CELF4,ZBTB38,SLC30A3,ITM2C,FAM13C,PHTF2,FRMD6,DPF3" MicroRNA hsa-miR-517*:mirSVR_highEffct hsa-miR-517*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-52 6.57E-49 5.17E-52 4.76E-51 136 779 "KCNH8,NDRG2,KLHL32,ADRB2,OSBPL8,MAGEE2,PPP4R4,CFLAR,MTMR2,GYG2,ZNF555,HIP1R,RUNX1T1,LDB2,CD86,CBFA2T2,TAOK2,PLAA,CLCN3,MAGED1,ANKRD44,GDA,CRYM,ARHGEF10,VCAN,PDE4DIP,HDAC9,KATNAL2,YTHDC1,DDX46,RHOBTB1,SACS,GRIN3A,NYAP1,DNAJB6,ABCC5,EDNRB,FCF1,FSD1L,YAF2,VPS13B,MRPL37,CDKL3,DNAJC27,EXTL2,CLVS1,ACSL4,FCGR1A,FGF11,FGF12,FGFR3,IP6K2,EVL,NOP56,C2orf88,WDR83,UFM1,PDLIM5,CELF1,NSG1,SARAF,RAPGEF6,NEU3,MSTN,BRD8,CBX1,GNAL,LILRA2,ATP2B1-AS1,ATE1,AGBL5,NEGR1,SCIN,KCND2,LAMP2,STMN1,PACRG,MAT2A,MMP16,ZNF680,P2RX7,PDCD2,XRN1,PPARA,PRKACB,MAPK9,MASP1,APTX,C1orf109,PID1,ERI2,PBRM1,SETD5,CARF,PNMA8A,GSTCD,CCDC102B,LRRK2,ABCA11P,ATAT1,RTN1,ZNF331,WDR47,FAM214B,SLC22A4,RCOR3,ANKRD36,SNAP25,SOX3,KDM4C,ZNF423,SS18,ELOVL4,KANK1,PLCB1,CYB561A3,FAM200B,GPR161,TMEM9,RIMBP2,DCBLD1,PRR18,CLHC1,PLPPR2,NPDC1,CFAP298,ZNF711,TRIM9,REEP1,EMSY,WNK3,PLSCR4,PARP11,FAM13C,DOCK8,RNF146" MicroRNA hsa-miR-657:mirSVR_highEffct hsa-miR-657:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-52 7.73E-49 6.07E-52 5.59E-51 130 713 "KCNH8,CLK4,AS3MT,NCKAP5,BRAP,ZNF608,INTS2,KIAA1324,OSBPL8,TXNDC16,AMT,USP37,CDC14B,SEMA4G,EIF4G3,NRP2,PROM1,CAST,USP6,DGKI,CCPG1,NOG,QKI,SULT4A1,ARHGEF6,CNTN1,AKAP6,TBPL1,DZIP3,KIAA0040,ERC2,CCDC144A,ARHGAP32,RIPOR2,DCAF8,MYEF2,RHOBTB1,SPOCK3,PDCD6IP,KLHL5,PHF20L1,EGFR,CALCRL,LRRC17,F8,FAM198B,TAOK3,ZNF589,GORAB,GTF2IRD2,FHL1,NBEA,SMC2,ATP2C1,ZNF605,ST6GALNAC3,GABRG2,ZNF234,LRRC37A6P,ARFIP1,AHDC1,DCLK2,GNG4,KAT7,PSIP1,MAN1B1,FAM69A,SLC35G1,METTL21A,A1BG-AS1,GPR155,MAN2A2,MEF2C,MEIS1,KITLG,MKLN1,MYO9A,NF1,OXTR,ZNF827,GPR85,CYTL1,POLG,MAPK4,QRICH1,TMEM260,PPP2R3C,PID1,OXR1,RADX,FIGN,YY1AP1,RPL15,SPIN3,MCMBP,ATAT1,KCNIP3,SEMA6D,CSRNP3,SHMT2,CHD9,CCDC92,SEPHS1,CCDC88A,MTERF2,BTBD7,KDM4B,DOP1A,ZNF423,DBNDD2,LARP4,SSPO,STAU1,ZSCAN29,COBL,C12orf76,ZFP90,FRYL,PMS2CL,FAM155A,VSNL1,ZBTB14,ZNF142,STOX2,PPP1R3F,KCNAB1,PLSCR4,UBE3B,TTC7A,FRMD6" MicroRNA hsa-miR-629:mirSVR_highEffct hsa-miR-629:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-52 8.08E-49 6.34E-52 5.84E-51 135 769 "RALGAPA1,SYS1,DPY19L2P4,MTUS1,KLHL13,OSBPL8,ALCAM,KCNAB2,TNRC6C,SPTBN4,ZFYVE28,CADPS,INSYN2B,ATP6V1G2,RIPK1,SEC11C,MTMR2,KALRN,CD86,DIS3L,SRSF11,CNTN1,IQCK,COL4A5,LETMD1,GAL3ST1,NCOR1,GDA,CSF2RA,SUSD5,APPL1,LONRF1,DGKB,KIAA0753,WDR20,NR1D2,CPEB2,EDNRA,TMTC1,SUGP2,EIF1,ABCA8,FGF1,POLK,UBE2E3,AGAP3,ATP2C1,STAU2,GABRB3,C15orf41,ALDH1L1,ADAM28,CSDC2,RNPS1,SPIN1,GLUL,LUZP2,GP1BB,TDRKH,PCLO,PLCD4,GRIN2D,KAT7,MUM1,RASSF8,HNMT,ZDHHC15,SMAP1,ZIC5,RBPJ,STXBP5,PAXBP1,MID1,BLOC1S2,P2RY13,NTRK3,PAX6,DPY19L2P2,ENPP2,PIK3C2A,FAM218A,SNX10,MTRF1L,STRN3,PPM1B,MAPK10,MASP1,PTPRD,PPP2R3C,ZMAT4,RNASEL,KLHDC8A,BAALC,ATAT1,KCNIP3,CCDC112,FAM102A,MYO18A,FHOD3,ANKRD6,FAM81A,BTBD3,WDR47,SLC8A1,SLC14A1,ZFP1,RCOR3,HECW1,NKAIN2,ELOVL4,CEP68,SULF2,NECAB1,ADAMTS17,COBL,TACR1,TCF4,PCDHB9,SLC19A3,USP32P1,GPRIN3,TMPO,WBP2,PLEKHH2,ZNF781,RICTOR,ZIC2,ZNF70,EML6,LAMP5,FZD3,MARCH8,PHTF2,NETO2,NETO1" MicroRNA hsa-miR-129-5p:TargetScan hsa-miR-129-5p TargetScan 1.68E-52 9.37E-49 7.35E-52 6.77E-51 111 516 "ACTN1,NDRG3,KLHL32,ADCY5,BEND6,PHF12,APC,MARCH3,NCOA1,INSYN2B,EIF4G3,FUBP1,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAST,RUNX1T1,CDH2,DLGAP2,CACNA2D2,LHX2,NRXN3,CLTC,MYRIP,NRG2,CLOCK,PLXNA4,PLCXD3,RIMS2,CCDC144A,KIF26A,LIN54,MATR3,KIAA0586,MFAP3L,DMD,EBF1,EDNRA,PAN3,EPHB1,ERBB4,ETV1,NRN1,DLC1,MED12L,AMOTL2,PCYOX1,C2orf88,CELF1,AHDC1,GFRA2,PCDH17,GHR,GLYR1,GLUL,KIAA1958,KDM2B,GPR37,FRMD3,BACH2,IL6ST,LIMS1,MBNL1,MEIS1,MXI1,NFIX,NPTX1,PAX6,PCDH8,PDE4A,PDPK1,LRP12,APTX,OXR1,GTDC1,FIGN,FBXW7,MAP6D1,SATB1,SCN8A,SEC14L1,CPEB3,DHX30,CCDC88A,CXXC4,MYCBP2,ERC1,ARHGAP26,NXT2,ADHFE1,NSFL1C,NUDT10,FAM208A,RPGRIP1L,GPRIN3,FRYL,NACC2,BHLHB9,CSMD1,KAT6B,NR2C2,PPIL6,FAM155A,RBFOX3,KCNK12,ANKS1B,HNRNPA3,GAN,JPH3" MicroRNA hsa-miR-331-3p:mirSVR_lowEffct hsa-miR-331-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-52 9.54E-49 7.48E-52 6.88E-51 162 1094 "SYN3,ASIC1,XKR4,GALNT16,AP2A1,SEMA6A,AMPD3,SUGT1P4-STRA6LP-CCDC180,APOC1,CASK,ARNTL,ARRB1,MARK4,KSR1,DST,AP1M1,DDR1,LDB2,USP2,DGKI,SEPT7,LRRFIP1,LARGE1,UBE2L6,TPP1,MYL6B,DGCR9,IGLON5,CNR1,ARMC8,COL11A2,MYRIP,GDA,POM121,RHOBTB1,KIF19,ZNF582-AS1,SLC25A18,FAM78B,PHC2,KMT5B,ING4,ERBB2,NCALD,VPS26C,F8,TMEM132C,PTK2B,CHST15,FCGRT,PRMT5,GORAB,FLNC,ZNF605,CELF1,GFER,MMADHC,CRCP,STARD3,POLL,KCNMB4,LILRB4,ADAP1,AP4S1,SOX21,ATXN2L,AGBL5,SMAP1,IRF8,MSL1,GAREM2,C2CD4C,ITPKB,CAMK2N2,NCOA7,LSS,MAN2A2,MAP6,MEIS2,MPP2,MSI1,PTOV1,NRBP2,LAYN,HNRNPM,P2RY13,NCAM2,CLDN11,NLE1,FSD1,MINDY2,PRKAR1B,GRAMD1C,HYDIN,MTMR10,PTPRD,C1orf109,ZSCAN2,TTC13,MARCH1,GTDC1,RGS3,RGS12,TMLHE,PNMA8A,EPHA10,STX1B,ATXN7,CASC3,MYO18A,HKDC1,CHD9,FNDC3A,FAM214B,KANSL3,PKNOX2,SLC8A1,ABTB1,CDK5RAP2,MBD5,SNRPN,KDM4B,ZSWIM8,NMNAT2,SPTAN1,TSPYL2,NFASC,LHPP,CLSTN2,ITPRID2,ERBIN,ZSCAN29,SEPT8,DIP2A,KANK1,PRRC2C,SYNE2,RHBDL3,SYN2,SYPL1,TACR1,PDLIM2,ADGRL3,NAT16,TNS2,PMS2CL,RELL2,FAM124A,CABIN1,NPL,METTL3,LINC00689,ZNF711,ATP6V0E2,ZNF213,DHX33,MAP3K12,EMSY,SLC17A7,PCBP4,LAS1L,PRRT4" MicroRNA hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA_TOP PITA 1.72E-52 9.61E-49 7.53E-52 6.93E-51 108 487 "ACTN1,XKR4,KLHL32,ELFN2,ESYT2,ZNF608,PCDH19,TAOK1,SPOP,APC,ZBTB10,NCOA1,EIF4G3,BCHE,BCL7A,CACNB4,CALM1,RUNX1T1,DLGAP2,FOXN3,LHX2,CLTC,QKI,CNN3,AKAP5,NRG2,ZNF385A,LRIG1,RIMS2,GAPVD1,ARHGAP24,KIF26A,MATR3,MFAP3L,ZC3H11A,SPOCK3,ABCC5,KLHL5,YAF2,EGR3,EPHB1,ETV1,NRN1,ACSL4,TAOK3,MED12L,AMOTL2,MEGF11,AHDC1,PCDH17,TMEM121B,RNF165,BACH2,MIER3,IGF1,RBPJ,LIFR,MAP2,MBNL1,LRP1B,MEIS1,MEIS2,MXI1,MYO5A,NEXMIF,NFIX,OCRL,PDPK1,PIK3R1,PDZRN4,LRP12,MINDY2,PTN,USP47,OXR1,ZMAT4,FIGN,FBXW7,KCNIP3,SCN8A,FNIP1,TRA2B,CPEB3,CCDC88A,TET1,SNCA,SOX11,SP4,MYCBP2,NKAIN2,SYT1,CAMTA1,ADGRL3,TCF4,RPGRIP1L,GPRIN3,ZNF106,LRRC8A,KAT6B,NR2C2,SGK3,FAM155A,FLRT2,ZIC2,CELF4,ANKS1B,STOX2,HNRNPA3" MicroRNA hsa-miR-767-5p:mirSVR_highEffct hsa-miR-767-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-52 1.05E-48 8.21E-52 7.56E-51 132 737 "KCNH8,NCKAP5,FMNL2,GALNT13,PWWP2A,KIAA1324,C1QTNF3,SRPX,FAM135A,SYT13,AMPH,UPRT,NUMB,STX16,ATP2A2,N4BP2L1,ADGRB3,LINC00847,ARHGEF7,NAE1,CACNA1B,PTBP2,SLC25A14,MTMR7,CDC25B,ARHGAP33,NUMBL,COL4A5,SLC4A8,AHCTF1,ZFP28,CPS1,SEC31B,GDA,CSF1R,CSNK1G3,VAC14-AS1,USP6NL,HDAC9,RHOBTB1,SPOCK3,USP3,TUBD1,SCML2,FER,POLK,MEX3B,ANKFY1,FLYWCH1,JKAMP,CAMKK2,AP4B1,MSTN,ZNF276,GPR37,PCLO,BVES,RNFT2,HMGCL,SMAP1,ITGAM,KCNN2,KCNQ3,LAMA2,PAXBP1,SYTL4,MBNL1,MEST,MYCN,MYO6,NTRK2,NUCB2,CLDN11,OXTR,PCDH9,ENPP2,ZDHHC8,NALCN,PIK3C2A,PURG,PMP22,ING3,EPB41L4B,MINDY2,PPP2R2C,PRKAB2,MAPK9,SLC26A11,SAMD9,SNRK,BDNF-AS,SPDL1,PTX3,ACSM5,RADX,REV3L,GTDC1,RNASEL,ZNF568,HKDC1,NUBPL,DHX30,SEPHS1,NAPB,TET1,DOP1A,KDM4C,PEG10,SPTAN1,SST,PRRC2C,SYP,CAMTA1,SYNE1,CYB561A3,AP4E1,TPM1,NPL,TPM2,TRPS1,TUBB2A,UGT8,VLDLR,WIPF1,ZBTB14,ZNF24,LYPD6,EML6,EMSY,CASC15,RNF170,LAS1L" MicroRNA "AAGCACA,MIR-218:MSigDB" "AAGCACA,MIR-218:MSigDB" MSigDB 2.59E-52 1.45E-48 1.13E-51 1.04E-50 95 370 "ASIC1,ACTN1,GALNT13,SLC24A4,CASKIN1,KCTD16,SEMA6A,SYT13,PKP4,NUMB,DPY19L3,ADGRB3,SYNJ1,CACNA1I,KALRN,SPAG9,FOXN3,SOCS6,NRXN3,HAPLN1,RIMS4,PUM1,GAPVD1,DBN1,ELMO1,PLPPR4,SACS,HS3ST2,FAM13A,MBNL2,GOLGA7,MED12L,NEURL4,GABRB3,FREM1,PPARGC1A,GNAO1,GRIA2,RNF165,HLF,ELOVL5,SHISA6,KIT,LIFR,HECTD2,MBNL1,SCAMP5,MITF,NFIX,PCDH8,GPR85,ZDHHC8,PIK3R1,TRHDE,PPP2R2C,KANSL1,DIRAS2,RELN,ZMAT4,RET,ROBO1,ROBO2,RPS6KA2,ATAT1,ATXN2,SEC14L1,SHC4,FHOD3,ABLIM3,CCDC88A,SLC12A2,SOX11,LMO3,STXBP1,TACC1,SATB2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,RIMBP2,UBE2H,RICTOR,TRIM9,NDRG4,GDPD5,RNF103,NAV3,ITM2C,RTN4" MicroRNA hsa-miR-145-5p:TargetScan hsa-miR-145-5p TargetScan 2.91E-52 1.63E-48 1.27E-51 1.17E-50 125 663 "ABR,ACHE,FMNL2,MTUS1,HECW2,OSBPL1A,FAM135A,OGT,EPB41L5,ASGR1,N4BP2L1,DST,MYRF,CA12,CABP7,SCARB1,CDH2,CFL2,CLCN3,QKI,HECTD1,MAP4K4,PCYT1B,CABP1,COX4I1,AKAP12,APPL1,ARHGAP32,ARHGAP24,RASSF2,DNAL1,ELMO1,DDX46,MTX3,FAM107B,DPYSL2,RCAN1,EBF1,HIPK3,APH1A,GPHN,ERBB4,NCALD,ACSL4,CORO2B,DLC1,FER,FGF14,AMOTL2,PCYOX1,RGPD5,FLT1,ANKFY1,FUT9,ABLIM2,FYN,IGSF5,FREM1,GGT7,LYVE1,KIAA1958,HTATSF1,KCNMB4,GRB10,C1QL4,BACH2,MIER3,GABARAPL2,NEGR1,AGFG1,KCNB1,KCNN3,PAXBP1,MEIS1,MEST,MMP16,GIT1,SAMD5,BLOC1S2,MYCN,MYO5A,MYO6,GPR137C,PCDH9,PCSK5,PDE3A,PMP22,PSAT1,PPP3CA,MAPK4,PRPSAP2,NWD1,REV3L,RFX3,KLHL11,CCDC25,RORB,CLIP1,ATXN2,KIF21A,CPEB3,FNDC3A,NLGN1,CPEB4,EPC1,PEG10,ARHGAP26,CLSTN2,LARP4,DIP2A,ANKRD28,MCF2L,KIAA0930,DOCK9,FAM189A1,CRTC1,FRYL,ENHO,DOK6,AGMO,GDPD5,NAV3,FAM47E,RNF170,FXR1" MicroRNA hsa-miR-488*:mirSVR_highEffct hsa-miR-488*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-52 1.77E-48 1.38E-51 1.27E-50 135 774 "CLK4,MTUS1,FAM135A,ANK2,SUGT1P4-STRA6LP-CCDC180,EPB41L5,CDK13,ZBTB10,NCOA1,ATP1A1,ALDH7A1,ADGRB3,DST,CALB1,CAST,C1orf52,DLGAP1,CDR1,NOG,CHN2,FBXO7,MAP4K4,CNN3,ARMC8,SLC4A8,ABI3BP,BAG4,FAM171B,CREM,ANKRD44,DOCK4,ZFYVE16,SCRN1,SPATA2,HEPH,ZNF582-AS1,DPP6,DTNA,ECM2,EBF1,EDNRB,TMEM132E,RCAN2,EZH1,RACK1,FDFT1,GORAB,UBE2E3,C2orf88,CHL1,LILRA2,GPR37,RASSF8,GABARAPL2,LRRC75A,MYLK2,IL6ST,NME9,KCND2,SYTL4,MARK1,MBNL1,POC1B,LYRM9,NFE2L2,NOVA1,SLC11A2,OXTR,CDK18,PDCD2,PDE1C,RETREG1,EXOSC10,PPARA,PPP2R5E,PKIA,MAPK9,GDPD2,SNRK,BDNF-AS,PTPRG,PTPRN2,C1orf109,SLC25A48,USP47,SH3TC2,SLC25A36,SETD5,TMLHE,ARMC5,GSTCD,ELP2,CCDC102B,FBXW7,ZC3H14,ATP8B4,ATXN7,FNIP1,MRAS,ZFP30,CPEB3,SHC4,CHD9,TET1,IFT122,ANKRD36,SNRPN,SP4,KDM4C,NKAIN2,SS18,CEP68,TTBK2,FAM208A,KLHL4,TCEA1,RPGRIP1L,SYNE1,SIK3,ITGB3BP,ASXL3,BHLHB9,FAM124A,TPM1,PLEKHH2,MKRN3,SPHK2,ZNF177,SH3GLB2,MAP3K12,PRDM10,NAV3,PDSS2,FBXO36,NETO1" MicroRNA hsa-miR-1271:mirSVR_highEffct hsa-miR-1271:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.27E-52 1.83E-48 1.43E-51 1.31E-50 139 820 "ASPHD1,XKR4,KLHL32,ADCY6,SLC24A4,KIAA1324,C1QTNF3,ABCD2,ALK,AMPD3,LRCH2,FGD2,C6orf89,UPRT,VAT1L,STK33,DPY19L3,ADGRB3,DST,ARHGEF7,JAZF1,CACNB4,THSD7A,PTBP2,CAST,LDB2,MAGI1,CACNA2D2,NDST3,LY86,CNN3,COL9A1,ABI3BP,MYRIP,LRIG1,ERC2,APPL1,HDAC9,ARHGAP24,TM9SF4,DGKG,PLPPR4,E2F5,EDNRA,FAM13A,PHF20L1,CALCRL,GPHN,SRRM1,ZNF585B,FDFT1,FHL1,FOXF2,NOP56,SMC2,FAM49B,ST6GALNAC3,NSG1,FYN,B4GALNT1,DISC1,KIAA1841,SPIN1,ZNF782,GPR12,KAT7,RASSF8,HAS2,ZHX1,ELOVL5,HNMT,C2orf72,KTN1,MBNL1,TM6SF1,MEIS1,MITF,ZNF680,TAGLN3,HNRNPM,NF1,NOVA1,DNHD1,IGSF11,PCSK5,PFKFB3,PIK3C2A,FAM216A,PDZRN4,MAPKAP1,EPB41L4B,SH3KBP1,PTPRB,PTPRO,CEP97,RASGRF2,RIC8B,ZFHX4,BAALC,MCMBP,MRAS,SUPT20H,FHOD3,SYBU,DZIP1,NUBPL,FAM81A,PPP4R3A,BTBD3,IFT122,MYO16,TRERF1,SP4,SS18,ADHFE1,KLHL7,JMJD6,FBXW11,TBL1X,SIN3B,ZEB1,SLC19A3,PCDHB6,SIK3,FAM200B,TIMP4,TPM1,RUNDC3B,DCBLD1,RPL7L1,VLDLR,TRIM9,ZBTB38,TMEM198,ZFAND5,NAV3,JMJD1C,NETO2,GAN" MicroRNA hsa-miR-1827:mirSVR_highEffct hsa-miR-1827:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-52 1.85E-48 1.44E-51 1.33E-50 156 1024 "KCNH8,ASIC1,XKR4,ADCY6,GALNT13,PLEKHH1,ZNF608,KIAA1324,FAM135A,EP400,PPFIA4,SUGT1P4-STRA6LP-CCDC180,UPRT,TNRC6C,STK33,CHRD,ATP1B3,ZNF583,ADAM15,CFLAR,KSR1,JAZF1,GPC2,CA8,CALB1,THSD7A,CBS,CLDN10,MAGI1,DLGAP1,CCPG1,EPS15L1,FAM19A5,MAP4K4,CNN3,ARMC8,LETMD1,GAL3ST1,ANKRD44,CS,CYBB,GPRASP1,DCAF8,CENPL,EARS2,ELMSAN1,C2CD2L,TMCC2,USP3,ACOT8,DNM1L,EBF1,KLHL5,YAF2,EBI3,PLEKHA1,C8orf37,DCTN4,SLC43A2,PIPOX,SIRPB1,RACK1,FCGRT,STRADA,KAT8,SLC9B2,SPSB4,FGF14,SUCO,SYNCRIP,PSD2,ATP6V1H,STAU2,FAM120B,IQGAP2,INPP5K,TUBA8,GLI2,GPD2,TDRKH,CCDC184,PCLO,C1QL4,FAM19A2,RNF165,SMAP1,ZNF546,ZIC5,RBPJ,ZNF678,INSM1,NME9,ITGA7,KCND2,KHK,KTN1,HECTD2,SMAD1,MAN2A2,MATN2,MYO9A,SFR1,NELL2,NINJ2,NNAT,VWA2,CNOT4,SLC11A2,NTRK3,TBC1D25,OCRL,CDK18,PLCL1,PLIN1,PURG,SCHIP1,DCHS2,SNRK,ZSCAN2,ZNF615,TRIM68,DPF2,CARF,MRAP2,SCP2,CASC3,TRA2B,COPZ1,ZFP30,FUZ,SHC4,IFT122,SNRPN,ZC3H13,ZSCAN29,ADHFE1,KLHL7,SYT1,MTCL1,MCF2L,FAM208A,GPRIN3,FRYL,HEY1,NR2E1,KCNE5,SSBP2,CCDC136,ZNF154,STOX2,MDH1B,SLC17A7,EPM2A,RNF170,NETO2,JPH3" MicroRNA hsa-miR-3135:mirSVR_lowEffct hsa-miR-3135:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.53E-52 1.97E-48 1.54E-51 1.42E-50 151 963 "TMEM132B,GALNT16,ADCY6,AXIN2,USP31,MTUS1,CC2D2A,ADGRF5,LCORL,PHF12,BCAS1,ZFYVE28,CADPS,ZSCAN18,RASL11B,RNF182,CACNA1G,CA8,ISPD,CCNH,USP6,P2RX6,ENTPD2,LRBA,SEPT7,CDH2,MAGI1,CPNE6,FBXO7,ABI3BP,FAM171B,SEC31B,SEC24C,ARHGEF10,PNPLA8,RIMS2,CCDC144A,ARHGAP32,TCAF1,KIAA0586,GIT2,YTHDC1,RUSC2,GUCD1,DLX1,DMTF1,DPP6,DRP2,E2F5,CNNM1,TMTC1,YAF2,CELSR3,MRNIP,VPS13B,RASL12,REEP2,NSRP1,TUBB3,FCGR1A,FCGRT,ZNF589,SEC24B,AGAP2,FLT1,DCTN2,KHDRBS3,ST6GALNAC3,STAU2,TUBGCP4,SRCAP,USP19,PPARGC1A,STARD3,LILRA2,GSTM5,RASSF8,MIER3,EID2B,INPP5B,SLC35G1,STXBP5,SMAD1,MBNL1,ADAM11,SCAMP5,BLOC1S2,HNRNPM,NF1,OCRL,OPA1,P2RX7,PDE4D,GNG2,PFKFB2,SEMA5B,TMIE,PLXNB1,PILRA,PPM1B,PRKACB,BDNF-AS,ENOX1,RGS12,SETD5,EPHA10,ADAL,LRRK2,MAPK12,TNFRSF19,ASAP3,AMBRA1,SEPHS1,SLC9A5,SLC11A1,ELMO2,RCOR3,ANKRD36,LIMCH1,TSNAXIP1,CLSTN2,POGZ,NKAIN2,TACC1,SIN3B,CUX2,NAT16,SLC44A1,ENHO,TPM2,SMUG1,ELP5,TRPM2,SGK3,CLEC2L,GORASP1,XRCC4,LGI4,ZIC2,ATP6V0E2,SH3GLB2,NT5M,GDPD5,LINC02210,HPS4,SLC17A7,DOCK8,CASC15,TRAM2-AS1,TIGD6,AP3B2" MicroRNA hsa-miR-3157:mirSVR_highEffct hsa-miR-3157:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.61E-52 2.02E-48 1.57E-51 1.45E-50 145 891 "ACADM,RNF150,RTL9,TBC1D14,KIAA1324,ALCAM,ANK2,PHF12,PHYHD1,CHRD,RASL11B,N4BP2L1,ADAM23,CFLAR,MTMR2,PTBP2,VXN,CCK,CNOT8,LHX2,TPP1,STOML1,CNR1,AKAP6,SLC4A8,RBM39,AKAP12,SEC24C,VAC14-AS1,GREB1,DOCK4,KATNAL2,ZFYVE16,INTS1,DGKB,DBI,GIT2,ARMCX4,FBXL5,EXOG,DNM1,EDN3,FCF1,EGFR,EIF4G1,STARD3NL,NSRP1,FDFT1,PPP1R1B,OLFM1,FGF12,NELFCD,TMEM107,SPECC1,TRIM16,MSANTD4,FAM120B,RAPGEF6,DISC1,IGSF5,ADAM28,GHR,HPGDS,TOX3,ZNF638,STMN2,GRM8,SOX21,TOX2,ZHX1,MIER3,SCIN,KCNQ3,CYP27C1,SYTL4,NCOA7,MBD1,MEIS2,POC1B,MSI1,MXI1,LYRM9,NPY,NOVA1,DNHD1,CDK18,PDE1C,PDE4D,TMEM38A,PDZRN4,PPM1B,TATDN3,PPP3CA,DCHS2,RELN,SNRK,PIGG,C1orf109,PID1,KHDRBS2,RIC8B,RNASEL,ELP2,SPIN3,ADAL,ATAT1,SCN8A,SUPT20H,SCAF8,KIF21A,SH3GL3,SHC4,WDR47,ATF7IP,CPEB4,ZFP1,CDK5RAP2,SNAP25,SNRPN,KDM4C,CDK19,ATP10B,LARP4,NKAIN2,NUDT10,AGTPBP1,PCDHB4,FRYL,TEK,ZFPM2,ITGB3BP,R3HDM1,TPM1,SYNPO2,TTC3,SLC47A2,ZNF711,MKRN3,SLC30A4,RNF103,URM1,TRIM16L,FAM13C,MARCH8,ACTR3B" MicroRNA hsa-miR-331-5p:mirSVR_highEffct hsa-miR-331-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.69E-52 2.62E-48 2.04E-51 1.88E-50 140 834 "RALGAPA1,ACADM,NCKAP5,KLHL32,PWWP2A,OSBPL1A,C1QTNF3,ALCAM,ABCD2,MAP4K3,TNRC6C,USP37,PPP4R4,ARRB2,ASGR1,SYNJ1,NAE1,PTBP2,FHL5,ABI3BP,IGDCC3,CNRIP1,CREM,CSNK1G3,KIAA0408,HDAC9,DCAF8,LONRF1,LIN54,PABPC5,JAKMIP2,RUSC2,NR1D2,DPP6,ARRDC4,ECM2,DNAJB6,DNM1L,RASGRP1,FAM13A,RASA4,PLEKHA1,PAN3,RABEPK,DNAJC27,FAM198B,ZNF461,ZSCAN30,GORAB,FER,FGF12,SLC37A3,ATP6V1H,TVP23A,ZNF44,TUBGCP4,ARFIP1,GGTA1P,LYVE1,BRD8,HPGDS,TOX3,WDFY3-AS2,HAS2,MIER3,ELOVL5,DHX35,INSM1,LAMA2,GPR155,MAP4,SHC3,SRSF12,MID1,POC1B,MYCN,CNOT4,SLC11A2,NTRK2,OCRL,LOC100128398,CNTN3,CDK18,PFKFB3,ABCB1,ZNF655,TRHDE,LRP12,PPP1R1A,RANBP3L,GRAMD1C,RELN,VPS13C,BDNF-AS,TMEM260,PTPRB,RBBP8,RET,ERI2,RNASEL,CCDC102B,MRAP2,LRRK2,TRAPPC13,FNIP1,ASAP3,CPEB3,BTBD3,DHX30,SPART,PBLD,ELOVL4,NUDT10,SYPL1,AGTPBP1,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,SIRT1,TLR4,KAT6B,CLHC1,LYPD6,CELF4,REEP1,ZNF225,RNF103,PPP1R3F,DNAH10,SMIM8,PHTF2,FBXO36,CASC15" MicroRNA hsa-miR-199a-5p:mirSVR_highEffct hsa-miR-199a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.18E-52 2.90E-48 2.25E-51 2.07E-50 137 800 "RALGAPA1,KCNH8,ASPHD1,KLHL32,CCDC85A,PTCHD1,OGT,MAP4K3,PHF12,APOC1,PPFIA3,BACH1,FUBP1,JAZF1,DDR1,NFS1,CERS5,LRRFIP1,LARGE1,CCPG1,CFL2,COPB2,CHN2,CNOT8,PPT2,CLTC,FAM149A,PREPL,HAPLN1,RGS6,UBXN2A,RUBCN,CYBB,HDAC9,GPRASP1,GAPVD1,RASSF2,TBC1D5,YTHDC1,MYEF2,KIAA0753,SACS,FAM107B,E2F6,TSPAN5,OPTN,PAN3,USPL1,SRRM1,IGSF6,RACK1,FDFT1,TMEM164,SEMA4D,SLC37A3,NBEA,NSG1,SARAF,GAD1,ZNF559,NEU3,GCNT2,CSDC2,PPARGC1A,DBF4,TOX3,GLUL,GPD2,FUT10,GRIA2,PRDM5,FAM19A2,AGBL5,MSL1,METTL21A,KCND2,GPR62,KCNH2,KIT,PAXBP1,SYTL4,NCOA7,ZFYVE27,MAT2A,MBNL1,MEIS2,GIT1,NF1,SLC10A4,PCDH18,TRHDE,FA2H,PRKAB2,PIGG,MTMR10,ZNF844,SUSD4,FIGN,ROBO2,RORB,ELP2,MRAP2,NEK11,KCNIP1,CLIP1,SATB1,ZFP2,NLGN1,BTBD7,RCOR3,ERC1,CLASP2,LARP4,NXT2,ZSCAN29,ADHFE1,ZEB1,DNAH7,SIRT1,ZFPM2,ERCC6L2,TMPO,RUSC1,TSC1,TST,HIRA,XRCC4,PCDH20,ZNF19,ZNF177,PCBP1-AS1,MFF,STOX2,WNK3,FAM13C,PHTF2,ACTR3B" MicroRNA hsa-miR-377-3p:TargetScan hsa-miR-377-3p TargetScan 5.23E-52 2.92E-48 2.27E-51 2.09E-50 106 473 "RNF150,KCTD16,AK2,ABCD2,PCDH10,C6orf89,MADD,ARRB1,MARCH3,NCOA1,NRP2,FUBP1,MTMR3,JAZF1,CACNA1I,CA12,CACNA2D1,RUNX1T1,DLGAP2,CACNA2D2,B4GALT6,ARMC8,AKAP6,AKAP5,ENTPD4,PYGO1,C2CD2L,RAB39B,CDON,E2F6,EDNRB,SEMA3D,PLXNC1,AASS,C8orf37,EPB41,FGFR1,FLNC,NBEA,CELF1,NFU1,PPARGC1A,COPS8,GLYR1,GPR75,RNF165,RASSF8,FRMD3,IGFBPL1,NEGR1,MSL1,IGF1,KCNB1,KCNK3,KCNN3,KIF2A,KIFC3,IPO5,CAMK2N2,LSAMP,ADAM11,MMP16,MXI1,NOVA2,OCRL,PDE4D,GPR173,GPR85,LRP12,PKIA,PTPRB,RDX,FIGN,RFX3,KLHDC8A,HUNK,FAM192A,CSRNP3,NAPB,BTBD7,CPEB4,ARHGAP26,LARP4,MPRIP,DIP2A,PLCB1,ANKRD28,CAMTA1,FAM208A,RPGRIP1L,NSD1,PUM2,GPRIN3,BHLHB9,PRRT1,DOK6,EIF4ENIF1,PLEKHH2,REEP1,DPYSL5,CIAPIN1,KAT6A,JMJD1C,MSRB3,NETO1,GAN" MicroRNA hsa-miR-615-5p:mirSVR_lowEffct hsa-miR-615-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.46E-52 3.61E-48 2.80E-51 2.58E-50 153 992 "DGCR6,ACHE,ADCY6,ADORA1,ADRA1D,FAHD2CP,RTL9,ZNF578,TAOK1,SEMA6A,MARCH4,SYT13,PDZD4,AMPD3,APOC1,BCAS1,AQP6,CDK10,DPY19L3,KSR1,ARHGEF7,AP1M1,CACNA1I,CABP7,CAST,LDB2,P2RX6,LOC730101,SRSF11,CHRNA4,ARHGAP22,WHRN,TOGARAM2,ZNF521,SEC31B,CDC42BPB,CSF1,RGS6,GREB1,PUM1,HDAC9,HDAC4,KCTD8,IP6K1,AIF1L,ELMSAN1,RUSC2,GUCD1,SV2B,DNAH9,ECM2,DNAJB6,APH1A,EPB41L2,ENPP6,MRPL37,APC2,CHST15,FGF11,FGFR1,AMOTL2,TMEM175,UFM1,GABRB3,NEU3,GGT7,ZNF276,STARD3,GPD1,C1QL4,ADAMTS13,GRIN2C,LINGO1,SYNPO,IGFBPL1,CELF5,MYLK2,KNDC1,LRRCC1,DISP2,INPP5B,SLC6A17,KCND1,KCNQ3,KIFC3,L1CAM,ASPRV1,PIK3AP1,MBD1,MEF2C,DBNL,PTOV1,LAYN,HNRNPM,CCDC13,LOC100128398,PALM,ZDHHC8,NLGN3,PKD1,PKM,PNMA3,ING3,VSTM2L,MAPK7,MAPK9,PTCH1,RGS12,ARMC5,CARF,RPE,EPHA10,MEG3,HSD11B1L,ST6GALNAC6,KCNIP3,SCN8A,CASC3,SHMT2,FHOD3,SLC9A5,MAPKBP1,MBD5,FAM219A,IZUMO4,KDM4C,PBLD,DIP2A,STAC2,SYN1,ARC,ASTN2,ZEB1,SZT2,FAM189A1,SLC19A3,HIF3A,PMS2CL,DICER1-AS1,THRA,MTMR14,NPL,SMUG1,AMACR,WNT7A,GUSBP1,LGI4,SPHK2,ZNF189,DNALI1,ITM2C,PDSS2,FAM219B" MicroRNA hsa-miR-192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.41E-52 4.71E-48 3.65E-51 3.36E-50 153 994 "CLK4,AS3MT,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PHF12,PKP4,APC,IGDCC4,TMEFF1,ZFYVE28,ZBTB10,BARD1,BLM,DST,FUBP1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,RCBTB2,B4GALT6,FAM189A2,ABCG2,AKAP7,FAM171B,LRIG1,ARHGEF10,APPL1,CTH,DNAL1,DBT,PITPNC1,CDON,E2F5,PHC2,IRAK4,PCOLCE2,MFSD10,CEP85L,EXTL2,KATNAL1,CLVS1,ABCA8,CORO2B,ST3GAL6,CEP78,TMEM164,MEX3B,SEC23B,SYNCRIP,SEMA4D,SMC2,KHDRBS3,SARAF,KIAA1841,GATM,KIAA1958,KCNMB4,RAB40B,GPR37,CIT,FAM222A,RASSF8,ELOVL5,GAREM2,ZIC5,LRRCC1,IL6R,IL6ST,SLC35G1,KLHL23,KPNA5,TTYH2,LIMS1,MAN2A2,MEIS2,MXI1,SFR1,NEK1,NFYA,NUCB2,SETD4,OPA1,GPR137C,SNX10,KCTD15,GPSM2,PRIMPOL,MINDY2,EPDR1,MAPK9,VPS13C,PTPRE,RADX,TRIM68,RET,RIC8B,RNASEL,MAP6D1,RMI1,ATXN7,HES6,ZFP30,FERMT1,ANKRD6,WDR47,KDM4D,RADIL,ARHGEF40,SLC9A5,ZFP1,LIMCH1,FAM126B,FNBP1,SP4,SSTR2,SS18,TBL1X,SATB2,RPGRIP1L,DICER1,SIRT1,RP9P,C18orf54,ZMAT3,TMPO,ZNF346,STXBP4,UGT8,USP1,BCL2L13,CCDC14,XPO1,ZBTB14,ZNF45,LYPD6,REEP1,ZNF184,EML6,NT5M,STOX2,EPM2A,FAM182B,PHTF2,FBXO36,MSRB3,NHSL1,SPATA13" MicroRNA hsa-miR-1301:mirSVR_highEffct hsa-miR-1301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.63E-52 5.39E-48 4.17E-51 3.84E-50 144 886 "NDRG3,PWWP2A,TXNDC16,USP35,DPP10,ANK2,MAP4K3,IGDCC4,CDK13,ATP1B3,DST,SYNJ1,SYNJ2,C5,CCNH,LARGE1,SRSF11,CHN1,FBXO7,C4orf33,MAP4K4,LY86,RTTN,CREM,ABCG1,MROH8,PHACTR3,ZFYVE16,LIN54,DBI,AIF1L,JAKMIP2,SNAP91,HS3ST2,USP3,DTNA,ECM2,EBF1,TSPAN5,ANKRD46,HIPK3,YAF2,PHF20L1,EPHB1,SRRM1,DENND4A,DNAJC27,EXTL2,CEP78,FGF1,OLFM1,AMOTL2,SUCO,FLT1,JKAMP,FYB1,SDCBP2,HRASLS5,FAM120B,DISC1,CPLX2,IGSF5,PPARGC1A,ZNF638,ZNF782,GPD2,KAT7,SOX21,GUCY1B1,FRMD3,TNFAIP8L3,ARHGAP36,ZNF181,LRRCC1,KHK,KIF5A,STXBP5,PAXBP1,SMAD9,MAP2,MBNL1,MSI1,ADAM22,MT1M,MYO7A,NBL1,NF1,SETD4,RETREG1,FAM216A,ZNF426,DRAM2,PPP2R5E,RASGEF1B,GDPD2,CNTLN,PTK2,TMEM260,SLC25A48,RADX,NUDT11,ROBO2,MRAP2,BAALC,ATP8B4,NCBP3,ATXN2,SCP2,RASA3,SH3GL3,FBXO11,NUBPL,SLA,SLC12A2,SLC22A4,RCOR3,TEX2,CLASP2,ZNF302,NXT2,ELOVL4,SYNE2,KLHL4,SATB2,FRYL,TEK,DICER1,SIRT1,SLC44A1,MTMR14,CSMD1,C9orf85,ZNF346,VSNL1,ZBTB14,TRIM9,AGMO,SLC30A4,EMSY,HPS4,PLSCR4,PHTF2,PRRT4,FAM198A" MicroRNA hsa-miR-128:PITA hsa-miR-128:PITA_TOP PITA 1.50E-51 8.42E-48 6.52E-51 6.00E-50 109 507 "RALGAPA1,ADCY6,SPOP,PITPNM2,APBA2,TMEFF1,PDE8B,RNF182,DPY19L3,DOCK11,COPB2,FOXN3,SOCS6,HECTD1,CNR1,ARMC8,CABP1,ZNF385A,RGS6,SOCS5,ERC2,GAPVD1,SPATA2,DMTF1,DRP2,ABCC5,EGR3,TMEM132E,RCAN2,SRRM1,EZH1,DLC1,PRKAG2,UBE2E3,AGAP3,AFF2,SYT3,DOT1L,MEGF11,GHR,PPARGC1A,RUNDC3A,TPPP,GRIN2D,PTPRT,KAT7,MAP4K5,SMAP1,IGF1,IBA57,INSM1,MPP2,MXI1,ZC3H12B,NF1,NPTX1,NTRK3,KSR2,TBC1D25,OPA1,ZNF827,PDE3A,PDE1B,PIK3R1,RASGEF1B,DIRAS2,RELN,WBP1L,PTPRB,FAM184A,RDX,RET,KLHDC8A,RORB,SEMA6D,CASC3,FAM102A,SH3GL3,PPM1E,FNDC3A,CCDC92,CCDC88A,TRIM67,RCOR3,FAM126B,SP2,SP4,TEX2,POGZ,SS18,ELOVL4,PLCB1,SYT1,TAL1,PDLIM2,TCF4,CLASP1,FRYL,SIRT1,CBX5,FAM155A,CCDC136,TMEM237,DPYSL5,NAV3,KCNAB1,RTN4,KAT6A,NETO2" MicroRNA hsa-miR-510:mirSVR_highEffct hsa-miR-510:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.96E-51 1.10E-47 8.49E-51 7.81E-50 128 707 "CLK4,KDM5D,ADRB2,GPRASP2,BCAS1,CADPS,SLC4A4,DPY19L3,RGS11,KSR1,C5,WASF1,CLDN10,LDB2,USP6,MAGI1,CCPG1,SRSF11,PLEKHB1,CLTB,FAM149A,LETMD1,RTTN,GDA,CLIP3,CTH,GPRASP1,MATR3,KCTD8,DAPK1,ZC3H11A,GSDME,DDX46,EXOG,GRIN3A,DNM1L,GOLT1B,PHC2,ANKRD46,PHF20L1,RCAN2,LRRC17,EPHB1,F5,TUBB3,FGF12,IP6K2,SLC37A3,NELFCD,WDR83,JKAMP,SMC2,ATP2C1,HRASLS5,ZNF44,RAPGEF6,GATM,TNRC6A,CBX1,MAP7D2,GPD2,TDRKH,COQ10A,SCIN,KCNH2,MAT2A,MBD1,MBNL1,KCTD6,MXI1,NFE2L2,NINJ2,CNTN3,PDE1C,PDPK1,FAM216A,EPB41L4B,SH3KBP1,PPP2R5E,MAPK4,HYDIN,SAMD9,CNTLN,ZDHHC14,RET,C12orf49,PNMA8A,GSTCD,RORB,ELP2,HUNK,SCN7A,FNIP1,SLA,PPP4R3A,SLC8A1,ATF7IP,SMARCD3,RCOR3,DOP1A,PBLD,NEK4,ADHFE1,SLC37A2,C12orf76,TACR1,DNMBP,AGTPBP1,FBXW11,PCDHB7,PCDHAC2,USP32P1,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,FAM200B,ASXL3,TLR4,CCDC136,EMSY,DNALI1,URM1,ST8SIA2" MicroRNA hsa-miR-136*:mirSVR_lowEffct hsa-miR-136*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-51 1.23E-47 9.50E-51 8.74E-50 136 798 "NCKAP5,PSMG3-AS1,DPY19L2P4,INTS2,ANK2,PKP4,BCAS1,AQP6,CDC14B,PPP4R4,MARCH3,ATP2B2,BMPR1B,DST,ARHGEF7,BTK,CACNA1A,VXN,RUNX1T1,LARGE1,MAGI1,PPT2,CNTN1,ARMC8,COL4A5,RCHY1,CREM,RNF14,VCAN,PHACTR3,SLITRK5,CTH,CCDC144A,DOCK4,GAPVD1,DGKB,TIAM2,C2CD2L,SNAP91,DLX1,EXOG,DMD,USP3,DPYSL2,DTNA,FAM78B,DNM1L,GOLT1B,HIPK3,KLHL5,PHF20L1,EGR3,EMX2,LRRC17,ANKMY1,ADGRV1,ABCA8,ST3GAL6,IP6K2,EFCAB2,FAM49B,CELF1,ABLIM2,ZMAT1,GABRB3,DISC1,IGSF5,COPS8,TNRC6A,MAP4K5,C2orf72,NKD1,LRRCC1,KIT,STMN1,SMAD1,MAN2A2,AQP11,MBP,AFDN,MYCN,NF1,NFE2L2,PCDH9,PDE4B,SEMA5B,XRN1,SH3KBP1,PPM1B,MAPK9,WBP1L,STK32A,C1orf109,KHDRBS2,RFX3,CCDC82,ABCA11P,CLIP1,MRAS,FNDC3A,PPP4R3A,SOX3,THSD1,STAU1,ZSCAN29,DNAJC9,TAF9,ADGRL3,IQCE,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,AP4E1,TIAM1,SYNPO2,AMACR,TRPS1,VLDLR,XRCC4,ZIC2,LYPD6,CADM2,NAV3,WNK3,FAM13C,MARCH8,HNRNPA3,PHTF2,CASC15,SENP7" MicroRNA hsa-miR-196a:mirSVR_highEffct hsa-miR-196a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.20E-51 1.23E-47 9.50E-51 8.74E-50 136 798 "BRAP,CC2D2A,MAP4K3,APAF1,UPRT,TNRC6C,ARNTL,RASL11B,ATP2A2,DOCK11,RAB29,CALM1,PTBP2,SPAG9,LRBA,CCPG1,PPT2,FAM19A5,QKI,MAP4K4,FAM149A,AKAP6,ABI3BP,TBPL1,TRIM69,PDE4DIP,PPP6R2,USP6NL,CYBB,BOC,HDAC9,GPRASP1,KIAA0586,KLHL3,SNAP91,WDPCP,EDNRB,MBNL2,EPB41L2,LRRC17,ZSCAN30,SLC9B2,FHL1,HPCAL4,RGPD5,ANKFY1,C2orf88,ATP2C1,SARAF,FYB1,GABRB3,GALC,DISC1,NEU3,GHR,TOX3,PCLO,GRIA2,PRDM5,RNF165,PSIP1,DDX19B,NME9,SYTL4,MBNL1,LRP1B,POC1B,MYO9A,OPA1,P2RY1,GPR85,PIK3C2A,ZNF655,XRN1,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R5E,RANBP3L,SNRK,WDR25,ELOVL2,TMEM260,PTPRG,SH3TC2,ERI2,GTDC1,LGI2,EXD2,C12orf49,ATP8B4,S100B,PRCD,FNIP1,CASC3,GALNT10,KIF27,SLC14A1,ELMO2,MYH15,RBM34,TRERF1,HECW1,KDM4C,RBM26,LMO3,ITPRID2,DIP2A,KANK1,NECAB1,FAM208A,SMG6,KLHL4,ZEB1,SLC19A3,PUM2,SIK3,SIRT1,MTMR14,ERCC6L2,LRRC8A,TMPO,SYNPO2,HIRA,GORASP1,VSNL1,XRCC4,MKRN3,ANKS1B,SMARCAD1,STOX2,FAM13C,KAT6A,HNRNPA3,GAN" MicroRNA hsa-miR-543:TargetScan hsa-miR-543 TargetScan 2.24E-51 1.26E-47 9.69E-51 8.92E-50 114 559 "ABR,C3orf14,FMNL2,ADCY6,PWWP2A,ABCD2,CASK,DOCK11,BCL7A,IL33,LDLRAD4,CACNB4,CALB1,CAMK2G,CERS5,ARHGEF2,CDH2,DCLK1,DLGAP2,CHN1,NRXN3,ARMC8,AKAP6,AKAP5,RCHY1,AHCTF1,CLOCK,HAPLN1,OSBPL3,CTH,PYGO1,GAPVD1,RASSF2,MATR3,DNAL1,DBT,ELMSAN1,MFAP3L,DDX46,DLX1,NR1D2,CPEB2,KLHL5,PLXNC1,EIF1,EPB41,ERBB4,CEP85L,CLVS1,FGF12,PCYOX1,IQGAP2,PPARGC1A,RAB30,GNAO1,GPT2,GRM8,FAM222A,RASSF8,BACH2,HNMT,NEGR1,AGFG1,KCNQ3,IPO5,LIFR,MEIS2,MIA2,MXI1,PCDH8,PCSK1,PCSK5,PDE4D,GNG2,SCHIP1,PPP2R2C,CEP41,PKIA,CNNM2,PTPRD,EML5,FIGN,KLHL11,RORB,PTGR2,AP1AR,SCN2B,SCP2,HSPA4L,FAM102A,BTBD3,PKNOX2,CPEB4,ARHGAP26,RBM26,LMO3,DMXL2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,NACC2,CBX5,ASXL3,LRRC8A,FLRT2,LAMP5,PRDM10,RGS7BP,FXR1" MicroRNA hsa-miR-516b*:mirSVR_highEffct hsa-miR-516b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.45E-51 1.37E-47 1.06E-50 9.73E-50 141 857 "KLHL32,GALNT13,KIAA1211,AMPD3,ZFAT,PHF12,SUGT1P4-STRA6LP-CCDC180,PPFIA3,NUMB,ATP6V0A1,NAE1,WASF1,CFAP410,CAST,RUNX1T1,CCNH,AP4M1,ZBED1,CCPG1,CFL2,NDST3,CLCN3,COL9A3,MYRIP,CSNK1G3,DZIP3,PHF14,RIMS2,DCAF4,MYADM,ZFYVE16,DAPK1,BRINP1,HEPH,ZNF582-AS1,DMD,DOCK2,DPP6,DTNA,EDIL3,KLHL5,PHF20L1,MBNL2,PCOLCE2,DCTN4,LRRC17,RABEPK,STX2,GMPR2,NSRP1,RPS6KC1,ATP5PD,MEX3B,FLNC,SLC37A3,NOP56,SMC2,HVCN1,KHDRBS3,FAM120B,RAPGEF6,GFRA2,GHR,ZNF638,GPD2,TDRKH,CCDC184,PCLO,STMN2,GRIA2,HAS2,AGBL5,HSF2,KCND2,KCNN2,LAMP2,PAXBP1,PACRG,MAP4,AQP11,IDNK,PDE4B,ZNF655,PLCL1,SEPT4,MBOAT7,PPARA,PPP2R5E,APTX,TMEM260,PTPRE,PTPRN2,GTDC1,RGS12,ELP2,MRAP2,STK32B,LRRK2,ZNF354C,AP1AR,S100B,TNFRSF19,CASC3,CCDC88A,BTBD7,TET1,PEG10,NFASC,ZC4H2,DIP2A,SYT1,ASTN2,ANKRD12,MCF2L,AGTPBP1,TBL1X,DMXL2,SATB2,ZEB1,TPCN2,CLASP1,FRYL,FAM200B,CDH22,TMEM9,TLR4,NR2E1,TMPO,RIMBP2,STXBP4,TTC3,HIRA,PLEKHH2,CCDC14,KCNT2,ZNF189,SLC30A4,MDH1B,PARP11,KAT6A,NETO2" MicroRNA hsa-miR-516a-3p:mirSVR_highEffct hsa-miR-516a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.45E-51 1.37E-47 1.06E-50 9.73E-50 141 857 "KLHL32,GALNT13,KIAA1211,AMPD3,ZFAT,PHF12,SUGT1P4-STRA6LP-CCDC180,PPFIA3,NUMB,ATP6V0A1,NAE1,WASF1,CFAP410,CAST,RUNX1T1,CCNH,AP4M1,ZBED1,CCPG1,CFL2,NDST3,CLCN3,COL9A3,MYRIP,CSNK1G3,DZIP3,PHF14,RIMS2,DCAF4,MYADM,ZFYVE16,DAPK1,BRINP1,HEPH,ZNF582-AS1,DMD,DOCK2,DPP6,DTNA,EDIL3,KLHL5,PHF20L1,MBNL2,PCOLCE2,DCTN4,LRRC17,RABEPK,STX2,GMPR2,NSRP1,RPS6KC1,ATP5PD,MEX3B,FLNC,SLC37A3,NOP56,SMC2,HVCN1,KHDRBS3,FAM120B,RAPGEF6,GFRA2,GHR,ZNF638,GPD2,TDRKH,CCDC184,PCLO,STMN2,GRIA2,HAS2,AGBL5,HSF2,KCND2,KCNN2,LAMP2,PAXBP1,PACRG,MAP4,AQP11,IDNK,PDE4B,ZNF655,PLCL1,SEPT4,MBOAT7,PPARA,PPP2R5E,APTX,TMEM260,PTPRE,PTPRN2,GTDC1,RGS12,ELP2,MRAP2,STK32B,LRRK2,ZNF354C,AP1AR,S100B,TNFRSF19,CASC3,CCDC88A,BTBD7,TET1,PEG10,NFASC,ZC4H2,DIP2A,SYT1,ASTN2,ANKRD12,MCF2L,AGTPBP1,TBL1X,DMXL2,SATB2,ZEB1,TPCN2,CLASP1,FRYL,FAM200B,CDH22,TMEM9,TLR4,NR2E1,TMPO,RIMBP2,STXBP4,TTC3,HIRA,PLEKHH2,CCDC14,KCNT2,ZNF189,SLC30A4,MDH1B,PARP11,KAT6A,NETO2" MicroRNA hsa-miR-384:mirSVR_highEffct hsa-miR-384:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.31E-51 1.85E-47 1.43E-50 1.31E-49 148 943 "RALGAPA1,CCDC85A,PLEKHH1,TAOK1,ADGRF5,ZNF687,UPRT,PPP4R4,ARNTL,RGS20,DOCK11,WASF1,CALM1,CCNH,LRBA,L3MBTL4,MAGI1,CCPG1,NDST3,CLTC,QKI,MAP4K4,CNTN1,FAM149A,ANKRD35,ABI3BP,SLC35F1,PREPL,CREM,ABCG1,APPL1,PHF14,CTH,ZNF337,DAPK1,POM121,RHOBTB1,SACS,RAB39B,USP3,GOLT1B,EDN1,MBNL2,KMT5B,AASS,RCAN2,IGSF6,CLVS1,OLFM1,FGF12,FGFR1,UBE2E3,NOP56,SMC2,ATP2C1,FYB1,GALNT15,ZNF234,MTHFD2,GCNT2,GGT7,PPARGC1A,LYVE1,GRIA2,ATE1,PSIP1,IRF8,NKD1,KNDC1,KCND2,STMN1,NCOA7,MATN2,MEF2C,AFDN,MPP2,ZNF680,NF1,PRTG,NALCN,SMIM7,STRN3,EPB41L4B,PPM1B,PRKACB,MAPK9,HYDIN,APTX,DEF8,PTK2,PTN,ZIK1,ZNF615,MSANTD2,RGS12,ZNF532,ALG9,GSTCD,RORB,TCP11L1,LRRK2,KCNIP1,CLIP1,NCBP3,FOXRED1,NUBPL,PPP4R3A,SEPHS1,SLC8A1,CCDC88A,KBTBD4,NAPB,ANKRD36,LIMCH1,TRERF1,GLT8D1,CDK19,TROVE2,ZNF302,NKAIN2,ERBIN,ELOVL4,NEK4,STAC2,NECAB1,PLCB1,TACC1,DICER1,AP4E1,R3HDM1,NPL,AMACR,ANKRD20A2,UGT8,PLEKHH2,CCDC14,P2RY12,ZNF19,ZNF32,FSTL5,ZNF184,ZNF189,PRTFDC1,LINC02210,EPM2A,AMN1,HNRNPA3,TTC7A" MicroRNA hsa-miR-3137:mirSVR_highEffct hsa-miR-3137:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.21E-51 2.92E-47 2.24E-50 2.07E-49 124 669 "KIAA1211,BEND6,FAM135A,ZFAT,PKP4,APC,UPRT,APOC1,RASL11B,ADAM15,SYNJ2,CAST,NOG,SRSF11,CNGA3,COL9A3,TBPL1,SEC31B,PREPL,CREM,SOCS5,PDE4DIP,CYBB,KIF26A,TMEM170A,PABPC5,PLPPR4,USP3,DMTF1,GOLT1B,EBF1,WDPCP,FSD1L,FAM13A,EIF1,TUBD1,GPHN,FCGR1A,SUCO,HPCAL4,IQCG,FLT1,ZNF605,GALNT15,GABRG2,GALC,DISC1,KIAA1841,MSTN,GDF9,GRIA2,DIDO1,LINC01089,RASSF8,ELOVL5,ICA1,ZIC5,IL6ST,KHK,CYP27C1,MAT2A,SRSF12,MID1,PPM1L,XRRA1,ADAM22,MXI1,NF1,NUCB2,ZNF827,CDK18,SEMA5B,PIK3R1,PRIMPOL,DRAM2,PPP2R2B,RASGEF1B,GRAMD1C,HYDIN,DIRAS2,SNRK,MTMR10,PTPRD,TMEM255A,ENOX1,OXR1,TMLHE,CARF,RORB,MRAP2,NEK11,ZNF331,ATXN7,SCP2,ZFP2,HSPA4L,SH3GL3,FBXO11,ANKRD36,KDM4B,ZNF423,CAMTA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ERCC6L2,TP53BP2,HSPBP1,TOM1L2,LAT2,ZIC2,TRIM9,SLC38A1,LINC02210,STOX2,PLSCR4,PDSS2,FXR1,NETO1,SENP7" MicroRNA hsa-miR-99b*:mirSVR_lowEffct hsa-miR-99b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.82E-51 3.25E-47 2.50E-50 2.30E-49 117 595 "CLK4,NCKAP5,PWWP2A,FAHD2CP,CC2D2A,SRPX,CARNS1,OGT,SUGT1P4-STRA6LP-CCDC180,CDK10,TMEFF1,PDE8B,ZBTB10,BARD1,BCHE,RGS9,SYNJ2,RAB29,KALRN,L3MBTL4,ASIC3,LHX2,WHRN,COL9A1,CSNK1E,OSBPL3,SOCS5,RASGEF1C,PUM1,CYBB,KCTD8,DNM1L,EDN3,HIPK3,SRRM1,CLVS1,TAOK3,PRKAG2,APOPT1,STAMBP,CAMKK2,STAU2,CHL1,TRAF3IP2,FAM120B,CPLX1,GGT7,GLYR1,GLUL,ZNF638,CLASRP,HLF,AGBL5,HNMT,HP,IGF1,IL6R,KCNB1,KCNN3,KIT,MSR1,LYRM9,FXYD7,NCAM2,NELL2,NF1,NOVA1,NUCB2,ENPP2,JAKMIP1,EPB41L4B,FA2H,MAPK4,VPS13C,CNTLN,TMEM260,TRIM68,PRRT2,FIGN,GLDN,MAP6D1,SCP2,HSPA4L,ARX,CPEB3,CHD9,FNDC3A,EPN2,PKNOX2,SNRPN,USP33,NFASC,PBLD,ITPRID2,THSD1,PRRC2C,TAL1,TPCN2,TRIM2,SYNE1,DOCK9,CCDC173,R3HDM1,SSBP2,CCDC14,WIPF1,CLIP2,LYPD6,VPS35L,SEMA3B,PPP1R3F,KCNAB1,KAT6A,PHTF2,SOCS4,GAN,JPH3" MicroRNA hsa-miR-554:mirSVR_lowEffct hsa-miR-554:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.99E-51 3.35E-47 2.57E-50 2.37E-49 143 887 "EMILIN3,FMNL2,KLHL32,TMEM132B,GALNT16,ADCY6,MTUS1,KLHL13,CEP126,FAM135A,SUGT1P4-STRA6LP-CCDC180,APAF1,TMEFF1,CARMIL3,BMPR1B,SCAPER,LURAP1,CAMK2A,CARS,ISPD,PRC1,KYAT1,CD38,C1orf52,LRBA,CDH2,CDO1,QKI,RCHY1,CPS1,AKAP12,NCOR1,CSF2RA,SOCS5,FAM169A,PLCXD3,CYBB,CENPL,EARS2,SCRN1,JAKMIP2,MFAP3L,FBXL5,FAM107B,NYAP1,EDNRA,FSD1L,YAF2,TUBD1,IGSF6,MRPL37,EZH1,TAOK3,FCGR1A,IP6K2,FLT1,RASL10A,CELF1,SARAF,TUBGCP4,GGT7,DIDO1,KAT7,VSIG4,GABARAPL2,SYNPO,ZNF491,LRRCC1,CREG2,KIF2A,STXBP5,PAXBP1,SYTL4,SHC3,MEIS1,KCTD6,POC1B,MITF,NRBP2,PFKFB2,PKD1,LRRN3,PPP3CA,EPDR1,CNTLN,TMEM231,PPP2R3C,USP47,FAM66C,ZNF793,SH3TC2,RASGRF1,FIGN,CCDC82,ALG9,CARF,RORB,SPIN3,SALL1,MAPK12,SATB1,KIF21A,ASAP3,SLA,KDM4B,ERC1,DDN,VPS13A,SYPL1,ANKRD28,TCF4,SATB2,TPCN2,DOCK9,C18orf54,GPR161,TMEM9,HEY1,NR2E1,ERCC6L2,R3HDM1,RGMB,NR2C2,TRIO,TSC1,HIRA,FLRT2,PLEKHH2,ZNF709,BCL2L13,VSNL1,RICTOR,ZNF24,ZNF74,ZBTB38,TMEM237,POLR3H,ZXDA,NAV3,EPM2A,ADAMTSL3,NHSL1,NETO1" MicroRNA hsa-miR-19b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.15E-51 3.44E-47 2.64E-50 2.43E-49 128 714 "NCKAP5,MTUS1,HECW2,PCDH10,USP37,CCAR2,STX16,BCL7A,JAZF1,CALM1,PTBP2,EVI5L,CFL2,QKI,ARMC8,ZNF521,CLOCK,PPP6R2,DCAF8,HDAC4,RASSF2,LONRF1,GIT2,DBN1,SPATA2,YTHDC1,KLHL3,MTX3,WDR20,HIPK3,TMTC1,MBNL2,KMT5B,PLXNC1,CERCAM,VPS26C,KATNAL1,ACSL4,MED12L,SEC23B,TMEM107,RAPGEF6,AHDC1,MALT1,TNRC6A,PRUNE2,GRB10,CIT,ELOVL5,ZIC5,MBNL1,KITLG,AFF1,ZNF680,MYCN,IDNK,NF1,CNOT4,TBC1D25,OCRL,PDE4A,PDE4D,FAM218A,CCSER2,PKM,PURG,MBOAT7,SH3KBP1,PPARA,PPP2R5E,PRKACB,WBP1L,DEF8,PTPRB,PTPRG,RBBP8,KLHL11,RNASE1,ZFHX4,CLIP1,SATB1,ATXN7,SGK1,FAM102A,CHD9,FNDC3A,SYBU,BTBD3,EPN2,SLC6A8,NAPB,BTBD7,EPC1,KIF13A,ZNF423,CDK19,SPART,POGZ,MPRIP,ELOVL4,RGL1,DIP2A,ARC,ANKRD12,CAMTA1,EXOC7,ALG1,ATMIN,TCF4,DMXL2,TRIM2,DICER1,ZMAT3,SLC44A1,NACC2,CBX5,WBP2,TOM1L2,ZNF711,ZNF138,ZNF154,ZFAND5,MFF,STOX2,WNK3,FXR1,FRMD6,SOCS4" MicroRNA hsa-miR-381:PITA hsa-miR-381:PITA_TOP PITA 7.79E-51 4.36E-47 3.34E-50 3.07E-49 110 525 "CCDC85A,TRMT9B,LRFN1,CDC42BPA,EPB41L5,EIF4G3,STX16,CARMIL3,KALRN,LDB2,CNR1,ARMC8,ZNF521,CLIP3,OSBPL3,CSNK1G3,SOCS5,PLCXD3,DOCK4,ARHGAP24,YTHDC1,ZC3H11A,FAM107B,RAB39B,DMTF1,SLC12A6,DPP6,SNX29,MBNL2,KMT5B,EIF4G2,PAN3,EIF1,VPS13B,EPB41,SRRM1,DLC1,FOXF2,SYNCRIP,FOXO3,NBEA,MEGF10,CHL1,GABRB3,RAPGEF6,C15orf41,PCDH17,ADGRA3,PSIP1,MIER3,ZIC5,RBPJ,JAK2,KCND2,STXBP5,MARK1,MBNL1,MEIS2,MID1,MITF,AFF1,NEXMIF,ZC3H12B,CNOT4,PCDH8,KCTD15,PURG,PMP22,KANSL1,CEP41,SNRK,PTCH1,PTK2,RAP1GDS1,ZNF532,SALL1,SEMA6D,SATB1,FNIP1,SCAF8,PPM1E,CHD9,R3HDM2,WDR37,ABLIM3,SLC6A8,SP4,RBM26,LARP4,ANKRD12,TCF4,CRTC1,FRYL,ZFPM2,NACC2,R3HDM1,KAT6B,TP53BP1,UBE3A,USP1,TBC1D15,VSNL1,ZBTB38,EMSY,NAV3,KAT6A,PHTF2,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-300:PITA hsa-miR-300:PITA_TOP PITA 7.79E-51 4.36E-47 3.34E-50 3.07E-49 110 525 "CCDC85A,TRMT9B,LRFN1,CDC42BPA,EPB41L5,EIF4G3,STX16,CARMIL3,KALRN,LDB2,CNR1,ARMC8,ZNF521,CLIP3,OSBPL3,CSNK1G3,SOCS5,PLCXD3,DOCK4,ARHGAP24,YTHDC1,ZC3H11A,FAM107B,RAB39B,DMTF1,SLC12A6,DPP6,SNX29,MBNL2,KMT5B,EIF4G2,PAN3,EIF1,VPS13B,EPB41,SRRM1,DLC1,FOXF2,SYNCRIP,FOXO3,NBEA,MEGF10,CHL1,GABRB3,RAPGEF6,C15orf41,PCDH17,ADGRA3,PSIP1,MIER3,ZIC5,RBPJ,JAK2,KCND2,STXBP5,MARK1,MBNL1,MEIS2,MID1,MITF,AFF1,NEXMIF,ZC3H12B,CNOT4,PCDH8,KCTD15,PURG,PMP22,KANSL1,CEP41,SNRK,PTCH1,PTK2,RAP1GDS1,ZNF532,SALL1,SEMA6D,SATB1,FNIP1,SCAF8,PPM1E,CHD9,R3HDM2,WDR37,ABLIM3,SLC6A8,SP4,RBM26,LARP4,ANKRD12,TCF4,CRTC1,FRYL,ZFPM2,NACC2,R3HDM1,KAT6B,TP53BP1,UBE3A,USP1,TBC1D15,VSNL1,ZBTB38,EMSY,NAV3,KAT6A,PHTF2,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-31*:mirSVR_lowEffct hsa-miR-31*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.79E-51 4.36E-47 3.34E-50 3.07E-49 146 925 "SYS1,KLHL32,ADD2,PLEKHH1,RNF150,ADGRF5,SYT13,LRCH2,PPFIA4,APBB2,EPB41L5,CDC14B,ATP2A2,MYOM1,C5,CALB1,CDH2,ZMYM4,MAGI1,RAB33A,FAM19A5,IGLON5,COL9A3,RCHY1,CTH,ZSCAN23,DCAF4,CYBB,LONRF1,MAML1,DGKB,DGKG,MYEF2,SGSM2,DYNC1I1,CDON,ABCC5,HIPK3,CNNM1,ING4,EYA1,FGF12,FGF13,POLK,PCYOX1,TMEM107,PDLIM5,STAU2,ERAP1,GATM,ALDH1L1,TTBK1,KDM2B,MAP7D2,DIDO1,PSIP1,SYNPO,DHX35,SMAP1,MSL1,FAM95B1,IGF1,IL12A,SLC35G1,KIF5A,IPO5,LAMP2,HECTD2,MARK1,MBNL1,SRSF12,MITF,MSI1,MYO6,NEK1,NF1,P2RY1,CNTN3,ETFRF1,PCDH9,PDCD2,CCSER2,NLE1,STRN3,EPDR1,DIRAS2,CNTLN,PTCH1,ELOVL2,TMEM260,PTPN13,PTPRE,QDPR,ENOX1,OXR1,KHDRBS2,RNASEL,LGI2,CCDC82,DCUN1D2,TMLHE,BAALC,KIAA0895L,RXRA,RYR3,FAM192A,RMI1,SEC14L1,GALNT10,HSPA4L,SH3GL3,FBXO11,SLC2A5,DHX30,KANSL3,MBD5,SNRPN,BDP1,SPART,KLHL7,ARHGEF9,SYT1,MTCL1,KIAA1107,KLHL4,DMXL2,CLASP1,DOCK9,USP32P1,ZFPM2,AP4E1,TIAM1,BHLHB9,CDK20,C9orf85,TSN,RPL7L1,WRN,ZNF24,TRIM9,ADAMTS9,PARP11,PDSS2,PHTF2,FXR1,ST8SIA2" MicroRNA hsa-miR-1908:mirSVR_lowEffct hsa-miR-1908:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.14E-51 4.56E-47 3.49E-50 3.21E-49 138 830 "ACHE,CLK4,ADCY6,ADORA1,OLMALINC,AMPD2,PHF12,NT5C3B,PPFIA3,CDC14B,SEMA4G,PRX,MADD,ARRB2,LINC00173,CHID1,STX16,ATP6V0A1,TTLL9,GPR146,KSR1,ARHGEF7,RHBDL1,ARHGEF1,ENTPD2,DGKI,KCNAB3,CCPG1,CACNA2D2,ASIC3,TAOK2,EPS15L1,PPT2,IQCK,ZNF385A,CSF1,SLITRK5,PITPNM3,KIAA0040,DBN1,DNM1,NYAP1,FAM78B,TNK2,MFSD10,MTSS1L,RABEPK,RASL12,DLC1,FCGRT,FDFT1,OLFM1,AGAP2,FLT1,DOT1L,GHDC,INPP5K,CPLX2,ALDH1L1,TUBA8,GLYR1,STARD3,GPD1,GPER1,GRIN2C,GRIN2D,PSIP1,SLC2A6,PACSIN2,LRRC75A,SHISA6,MYLK2,KNDC1,C2CD4C,GATD1,KIFC3,LINC00634,XRRA1,LYRM9,RTL5,NOVA2,SETD4,PALM,NLE1,FXYD1,MTRF1L,PILRA,PPP5C,VSTM2L,SUSD4,RASGRF2,RFX2,SNX22,ATAT1,CLIP1,SH3GL3,ST6GAL1,ABLIM3,FAM81A,MAPKBP1,SP2,IQSEC2,MCF2L2,PHLDB1,STX1A,SYN2,SATB2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,CDH22,GALNT17,TIAM1,RELL2,LRRC8A,RASD2,IL34,WBP2,ELP5,AMACR,TTTY15,TOM1L2,VLDLR,LMF1,ZIC2,ZNF19,ZNF70,SPHK2,DPYSL5,WNK2,JPH3" MicroRNA hsa-miR-888:PITA hsa-miR-888:PITA_TOP PITA 8.83E-51 4.94E-47 3.78E-50 3.48E-49 99 420 "ABR,CLK4,USP31,ADRB2,ARHGAP20,GPRASP2,DPP10,LRCH2,NUMB,SLC4A4,SCAPER,KALRN,MAGI1,QKI,ZNF521,LRRC3B,SOCS5,DGKG,SCRN1,SPOCK3,FAM107B,DNAJB6,YAF2,CELSR3,MBNL2,SRRM1,ETV1,EXTL2,AFF2,OGA,MTHFD2,ARFIP1,PCDH17,PPARGC1A,TOX3,TNRC6A,MSL3,GPR37,GRIA2,SOX21,MAP4K5,PACSIN2,ELOVL5,GABARAPL2,CELF5,AQP11,MEF2C,MEIS1,MYCN,NDP,CNOT4,GPR137C,GNG2,TMOD2,XRN1,TRHDE,WBP1L,ELOVL2,TMEM260,OXR1,KHDRBS2,MSANTD2,REV3L,RGS4,ZNF532,RPE,RTN1,ATXN7,SCN2B,SCN8A,FNIP1,SUPT20H,PPM1E,CHD9,FAM81A,EPN2,SEPHS1,SNAP25,TMCC1,NMNAT2,ARHGAP26,CLASP2,SSTR2,SS18,PLCB1,SYN2,SYPL1,ADGRL3,SATB2,CLASP1,CSMD1,TSC1,UBE3A,ZNF711,LYPD6,REEP1,PRDM8,RNF103,PHTF2" MicroRNA hsa-miR-518a-5p:PITA hsa-miR-518a-5p:PITA_TOP PITA 9.25E-51 5.18E-47 3.95E-50 3.64E-49 108 506 "ASIC1,KLHL13,PCDH19,SRPX,DPP10,C6orf89,EPB41L5,CDC14B,CDK13,STK33,KSR1,LDLRAD4,HAP1,CAMK2A,DLGAP2,FOXN3,QKI,AKAP7,ZNF521,CRMP1,RIMS4,PUM1,SNPH,LONRF1,DGKB,FBXL5,MED12,FAM78B,MBNL2,KMT5B,EGR3,PAN3,ERBB4,NCALD,ACSL4,PTK2B,SCML2,OLFM1,FGF12,FOXO3,AFF2,NBEA,CPLX1,MSTN,GGT7,TNRC6A,KDM2B,FERMT2,CIT,RNF165,SOX21,MIER3,AGFG1,KCND2,KCNK3,KIT,STXBP5,MBNL1,CHIC1,MEF2C,MYCN,MYO5A,NEXMIF,NOVA1,TBC1D25,GPR85,PFKFB4,PIK3C2A,XRN1,PLEC,SMOX,PMP22,PPP2R5E,PTPRD,RDX,ZNF532,ROBO1,FBXW7,SALL1,SEMA6D,FAM102A,CHD9,FNDC3A,EPN2,WDR47,SLC8A1,CPEB4,RCOR3,SOX11,CDK19,PRRC2C,PLCB1,TACC1,ANKRD12,FBXW11,SIN3B,SATB2,TCF12,SYNE1,CRTC1,ZFPM2,TNS1,PCDH20,ZIC1,ADAMTS9,KCNAB1,RGS7BP,SENP7" MicroRNA hsa-miR-527:PITA hsa-miR-527:PITA_TOP PITA 9.25E-51 5.18E-47 3.95E-50 3.64E-49 108 506 "ASIC1,KLHL13,PCDH19,SRPX,DPP10,C6orf89,EPB41L5,CDC14B,CDK13,STK33,KSR1,LDLRAD4,HAP1,CAMK2A,DLGAP2,FOXN3,QKI,AKAP7,ZNF521,CRMP1,RIMS4,PUM1,SNPH,LONRF1,DGKB,FBXL5,MED12,FAM78B,MBNL2,KMT5B,EGR3,PAN3,ERBB4,NCALD,ACSL4,PTK2B,SCML2,OLFM1,FGF12,FOXO3,AFF2,NBEA,CPLX1,MSTN,GGT7,TNRC6A,KDM2B,FERMT2,CIT,RNF165,SOX21,MIER3,AGFG1,KCND2,KCNK3,KIT,STXBP5,MBNL1,CHIC1,MEF2C,MYCN,MYO5A,NEXMIF,NOVA1,TBC1D25,GPR85,PFKFB4,PIK3C2A,XRN1,PLEC,SMOX,PMP22,PPP2R5E,PTPRD,RDX,ZNF532,ROBO1,FBXW7,SALL1,SEMA6D,FAM102A,CHD9,FNDC3A,EPN2,WDR47,SLC8A1,CPEB4,RCOR3,SOX11,CDK19,PRRC2C,PLCB1,TACC1,ANKRD12,FBXW11,SIN3B,SATB2,TCF12,SYNE1,CRTC1,ZFPM2,TNS1,PCDH20,ZIC1,ADAMTS9,KCNAB1,RGS7BP,SENP7" MicroRNA hsa-miR-181a-2*:mirSVR_highEffct hsa-miR-181a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.26E-51 5.18E-47 3.95E-50 3.64E-49 133 773 "RALGAPA1,CLK4,NCKAP5,PWWP2A,RNF150,KCTD16,HACE1,BCAS1,ATP1A3,ALDH7A1,ADAM23,ADGRB3,MPDZ,RGS9,NRP2,BTK,KALRN,SLC25A14,CAPN3,ARHGEF2,LOC730101,CFL2,SRSF11,C4orf33,AKAP6,IGDCC3,ANKRD44,NCOR1,SNCAIP,CSNK1G3,SUSD5,PDE4DIP,CYBB,ZFYVE16,ARMCX4,ZNF804A,DDX46,DMD,NR1D2,DPP6,EDNRB,EGFR,KMT5B,COQ7,TAOK3,FGF11,ST6GALNAC3,SARAF,GALC,DISC1,GPR75,TNRC6A,MSL3,ZNF638,GNG4,GPR12,GRIA2,KAT7,HMGCL,AGBL5,ZDHHC15,MSL1,NKD1,IL6R,NME9,ITGA7,ITPKB,SLC35G1,HECTD2,SMAD9,MBNL1,NRBP2,THYN1,MXI1,MYO9A,NEK1,NFE2L2,NOVA1,CHAMP1,NALCN,PIK3C2A,SNX10,ING3,POLG,TATDN3,PPP2R2C,PRKAB2,PKIA,MTMR10,CEP97,TMEM255A,RAD17,RFX2,ZDHHC4,NUDT11,CCDC82,C12orf49,CARF,SALL1,SCN8A,SHC4,SLC9A5,SLC11A1,GKAP1,RCOR3,SNRPN,MYO16,TRERF1,BDP1,KDM4C,SSTR2,NKAIN2,NXT2,SYT1,TBCEL,DOCK9,USP32P1,CCDC173,AKTIP,SYNPO2,FAM155A,UBTF,WIPF1,GUSBP1,ZFP37,SPIRE1,SLC30A4,EPM2A,KAT6A,ADAMTSL3,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-506:PITA hsa-miR-506:PITA_TOP PITA 1.02E-50 5.71E-47 4.35E-50 4.01E-49 127 706 "ACHE,FMNL2,ESYT2,CASKIN1,PCDH19,OSBPL8,SEMA6A,ZNF687,LRFN1,CHRD,ATP1A1,DPY19L3,BCL7A,PTBP2,ARHGEF1,CDH2,LHX2,QKI,AKAP6,MYRIP,CLOCK,CLIP3,LRIG1,SOCS5,SLITRK5,PLCXD3,MYADM,GAPVD1,HDAC4,KIF26A,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,SPOCK3,GRIN3A,RCAN1,TOM1,E2F5,HIPK3,FSD1L,TENM1,PAN3,REEP2,PRKAG2,SUCO,PCYOX1,GABRB3,GABRG2,IQGAP2,ARFIP1,PCDH17,KIAA1958,GPT2,GPD2,GRIA2,GSN,RNF165,KAT7,BACH2,NEGR1,MYLK2,INSM1,ITGA7,KIF2A,MAT2A,CHIC1,POC1B,MITF,MYO9A,NFIX,NME4,NRCAM,PCDH8,PCDH9,PDE4B,PDE4D,PIK3C2A,RETREG1,XRN1,PLEC,SMOX,ANKRD16,EPB41L4B,SH3KBP1,TMEM104,MTMR10,TMEM260,PTPRD,DUSP15,UBR7,CLIP1,RYR3,SEMA6D,SCN2B,SCN7A,CASC3,GALNT10,SGK1,KIF16B,SHC4,FAM81A,SLC12A2,ATF7IP,TET1,FNBP1,LMO3,ITPRID2,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TCF4,NR2C2,SLC35A4,UBE3A,USP1,WIPF1,CLDND1,SMARCAD1,EVI5,TMEM63C,FXR1,ST8SIA2" MicroRNA hsa-miR-377:PITA hsa-miR-377:PITA_TOP PITA 1.26E-50 7.05E-47 5.37E-50 4.94E-49 103 459 "USP31,OSBPL8,MADD,MARCH3,NCOA1,NRP2,DST,JAZF1,WASF1,CACNA2D1,SPAG9,USP6,DLGAP2,CACNA2D2,SRSF11,FOXN3,B4GALT6,CNR1,AKAP6,DZIP3,APPL1,PUM1,SPOCK2,ELMO1,C2CD2L,ALKBH8,CDON,PHC2,EGR3,PCOLCE2,EPB41,ERBB4,KATNAL1,AFF2,NBEA,IQGAP2,SESN1,PCDH17,PPARGC1A,SPIN1,TDRKH,TPPP,PTPRT,RNF165,NXPH3,NEGR1,IGF1,ZIC5,IBA57,JAK2,KIF2A,IPO5,CAMK2N2,NCOA7,MITF,MSI1,NOVA2,SLC11A2,PRTG,PDE4D,GPR85,GNG2,PFKFB3,TRHDE,LRP12,WBP1L,PTPRB,RDX,RET,RIC8B,SETD5,PCMTD2,CSRNP3,ATXN7,SGK1,NLGN1,WDR37,NAPB,CPEB4,MBD5,SOX11,ARHGAP26,ITPRID2,STAU1,PLCB1,CAMTA1,TAL1,TBL1X,RPGRIP1L,TCF12,PUM2,FRYL,TIAM1,ASXL3,AMACR,EIF4ENIF1,OSBP2,TCEAL7,CELF4,REEP1,KAT6A,PHTF2,NETO2" MicroRNA hsa-miR-132-3p:TargetScan hsa-miR-132-3p TargetScan 1.27E-50 7.11E-47 5.41E-50 4.98E-49 92 359 "ABR,C3orf14,ELFN2,KIAA1211,OSBPL8,PCDH10,CDC42BPA,PTBP2,HIP1R,RUNX1T1,CBFA2T2,CFL2,FOXN3,B4GALT6,QKI,HECTD1,NRG2,CLOCK,HAPLN1,NCOR1,DOCK4,ARHGAP32,GAPVD1,DCAF8,ELMSAN1,SEC16A,DUSP9,E2F5,EDIL3,RASGRP1,CELSR3,PHF20L1,PAN3,NCALD,ETV1,EXTL2,OLFM1,FOXO3,AFF2,GHR,KIAA1958,GPD2,KAT7,HAS2,KCNN3,KIF2A,MSANTD3-TMEFF1,MAPT,MEIS1,MEIS2,KITLG,POC1B,MITF,MMP16,NFYA,NOVA1,NRCAM,PPP2R5E,PPP3CA,MAPK3,FITM2,PTCH1,MTMR10,PTPRD,KHDRBS2,RDX,PRRT2,GTDC1,RFX3,RORB,FBXW7,HUNK,SALL1,CSRNP3,ATXN7,ARX,CCDC88A,BTBD7,EPC1,MAPKBP1,NMNAT2,MYCBP2,CDK19,CLSTN2,SATB2,CRTC1,GPRIN3,NACC2,NDRG4,RGS7BP,KAT6A,FXR1" MicroRNA hsa-miR-212-3p:TargetScan hsa-miR-212-3p TargetScan 1.27E-50 7.11E-47 5.41E-50 4.98E-49 92 359 "ABR,C3orf14,ELFN2,KIAA1211,OSBPL8,PCDH10,CDC42BPA,PTBP2,HIP1R,RUNX1T1,CBFA2T2,CFL2,FOXN3,B4GALT6,QKI,HECTD1,NRG2,CLOCK,HAPLN1,NCOR1,DOCK4,ARHGAP32,GAPVD1,DCAF8,ELMSAN1,SEC16A,DUSP9,E2F5,EDIL3,RASGRP1,CELSR3,PHF20L1,PAN3,NCALD,ETV1,EXTL2,OLFM1,FOXO3,AFF2,GHR,KIAA1958,GPD2,KAT7,HAS2,KCNN3,KIF2A,MSANTD3-TMEFF1,MAPT,MEIS1,MEIS2,KITLG,POC1B,MITF,MMP16,NFYA,NOVA1,NRCAM,PPP2R5E,PPP3CA,MAPK3,FITM2,PTCH1,MTMR10,PTPRD,KHDRBS2,RDX,PRRT2,GTDC1,RFX3,RORB,FBXW7,HUNK,SALL1,CSRNP3,ATXN7,ARX,CCDC88A,BTBD7,EPC1,MAPKBP1,NMNAT2,MYCBP2,CDK19,CLSTN2,SATB2,CRTC1,GPRIN3,NACC2,NDRG4,RGS7BP,KAT6A,FXR1" MicroRNA hsa-miR-924:mirSVR_highEffct hsa-miR-924:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-50 7.65E-47 5.82E-50 5.36E-49 141 869 "ASIC1,EMILIN3,SPARCL1,SPOP,ABCD2,OGT,SUGT1P4-STRA6LP-CCDC180,APBA2,TNRC6C,TMEM108,ADAM23,DST,RUNX1T1,ZNF501,CLDN10,CD38,C1orf52,LRRFIP1,TIGD7,CCPG1,SOCS6,NDST3,ARMC8,FAM149A,LETMD1,AKAP5,RCHY1,ENTPD4,SNCAIP,RGS6,CSF2RA,CTH,GREB1,DOCK4,TCAF1,DCAF8,DAPK1,EXOG,NYAP1,GOLT1B,EBF1,YAF2,EGFR,RGS17,DENND4A,CDKL3,FER,SUCO,SLC37A3,C2orf88,ZMAT1,GALNT15,GAD1,IQGAP2,DISC1,GLUL,ZNF638,PSIP1,PADI2,AGBL5,ZDHHC15,EID2B,ZNF546,C2CD4C,ASPRV1,AQP11,EFHB,MEIS2,KCTD6,ZC3H12B,NDP,NF1,NFYA,P2RX7,CNTN3,PCSK1,PCSK5,PDE3A,PDE4D,PIK3C2A,PIK3R1,PMP22,POLG,PKIA,VPS13C,PTPRE,SUSD4,RAP1GDS1,EXD2,GSTCD,ROBO2,ELP2,RPL15,DGLUCY,SEMA6D,SGK1,SH3GL3,BTBD3,DHX30,WDR47,FAM214B,CCDC88A,ELMO2,SNAP25,NKAIN2,DIP2A,SEPT3,VPS13A,ADGRL3,FBXW11,KLHL4,CUX2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMEM121,AP4E1,ERCC6L2,TMPO,TPM1,RGMB,P2RY12,CLDND1,ZIC1,ZNF70,SPIRE1,SMARCAD1,PRDM10,RGS7BP,KAT6A,SMIM8,PHTF2,CASC15,TRAM2-AS1,RNF170,SENP7" MicroRNA hsa-miR-124:PITA hsa-miR-124:PITA_TOP PITA 1.41E-50 7.91E-47 6.01E-50 5.53E-49 127 708 "ACHE,FMNL2,ESYT2,CASKIN1,PCDH19,OSBPL8,SEMA6A,ZNF687,LRFN1,CHRD,ATP1A1,DPY19L3,BCL7A,PTBP2,ARHGEF1,CDH2,LHX2,QKI,AKAP6,MYRIP,CLOCK,CLIP3,LRIG1,SOCS5,SLITRK5,PLCXD3,MYADM,GAPVD1,HDAC4,KIF26A,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,SPOCK3,GRIN3A,RCAN1,TOM1,E2F5,HIPK3,FSD1L,TENM1,PAN3,REEP2,PRKAG2,SUCO,PCYOX1,GABRB3,GABRG2,IQGAP2,ARFIP1,PCDH17,KIAA1958,GPT2,GPD2,GRIA2,GSN,RNF165,KAT7,BACH2,NEGR1,MYLK2,INSM1,ITGA7,KIF2A,MAT2A,CHIC1,POC1B,MITF,MYO9A,NFIX,NME4,NRCAM,PCDH8,PCDH9,PDE4B,PDE4D,PIK3C2A,RETREG1,XRN1,PLEC,SMOX,ANKRD16,EPB41L4B,SH3KBP1,TMEM104,MTMR10,TMEM260,PTPRD,DUSP15,UBR7,CLIP1,RYR3,SEMA6D,SCN2B,SCN7A,CASC3,GALNT10,SGK1,KIF16B,SHC4,FAM81A,SLC12A2,ATF7IP,TET1,FNBP1,LMO3,ITPRID2,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TCF4,NR2C2,SLC35A4,UBE3A,USP1,WIPF1,CLDND1,SMARCAD1,EVI5,TMEM63C,FXR1,ST8SIA2" MicroRNA hsa-miR-182:PITA hsa-miR-182:PITA_TOP PITA 1.50E-50 8.37E-47 6.35E-50 5.85E-49 105 479 "ADCY6,KLHL13,PDZD4,CDC42BPA,ARHGDIA,NUMB,ATP1B3,JAZF1,CALM1,ARHGEF2,SEPT7,FOXN3,SOCS6,QKI,MAP4K4,CNN3,BAG4,MYRIP,IGDCC3,CLOCK,PREPL,AATK,LRIG1,CSNK1E,ERC2,USP6NL,MYADM,GIT2,ELMO1,RHOBTB1,KIF19,YAF2,APH1A,MBNL2,EGR3,EIF5,RGS17,EPHB1,SLC43A2,NCALD,EZH1,NRN1,FOXF2,FOXO3,KHDRBS3,CHL1,TOX3,KDM2B,LPAR4,BACH2,ZIC5,KTN1,L1CAM,SMAD1,CHIC1,MEF2C,MEIS2,MITF,TAGLN3,NF1,NPTX1,NRCAM,OCRL,PCDH8,GPR173,GPR85,TMOD2,RETREG1,PCDH18,LRP12,PTCH1,TMEM145,OXR1,RDX,ZMAT4,FIGN,SNX22,FBXW7,SPIN3,MCMBP,PPM1E,SHC4,WDR47,SEPHS1,FAM126B,SOX11,TEX2,ERC1,SYPL1,CAMTA1,ADGRL3,FBXW11,SATB2,DOCK9,HEY1,TNS1,VLDLR,WIPF1,CADM2,EVI5,STOX2,FZD3,RTN4,FXR1,ST8SIA2" MicroRNA hsa-miR-483-5p:mirSVR_lowEffct hsa-miR-483-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-50 9.77E-47 7.40E-50 6.82E-49 139 847 "ACHE,NDRG3,NDRG2,OSBPL1A,SORCS2,FAM135A,CCDC146,KCNAB2,PHYHD1,BCAS1,PPFIA3,CPNE5,CDK13,MARK4,CHID1,STX16,SLC2A11,ALDH7A1,ADAM23,ADGRB2,RGS11,BLM,RAB29,KALRN,PTBP2,RHBDL1,CBS,ZBED1,NOG,SOCS6,MAP4K4,ABI3BP,ENTPD4,ANKRD44,ABCG1,MAML1,TMEM130,POM121,SGSM2,SLC29A4,DPYSL2,DNM1L,FIS1,PHF20L1,SUGP2,RASA4,IRAK4,DNAJC27,TLR7,SIRPB1,KATNAL1,CD320,HSPA12B,FAM198B,ZNF461,CHST15,GTF2IRD2,CINP,TPK1,ZNF605,KHDRBS3,FAM120B,KIAA1841,ZNF276,TNRC6A,KDM2B,CLASRP,RNF165,SLC2A6,MAN1B1,HMGCL,AGBL5,IRF8,RBPJ,INPP5B,ITPKB,KCNJ5,KCNK3,LIMS1,GPR155,MARK3,SRSF12,NPTX2,PCBP3,LOC100128398,DPY19L2P2,OLA1,ZNF655,PNMA3,ANKRD16,POU6F1,SNRK,MTMR10,CCDC40,ZNF793,RASGRF2,KHDRBS2,GSTCD,SNX22,CLIP1,RYR3,CASC3,FNDC3A,NUBPL,NAPB,MAST1,SNRPN,ZSWIM8,SEPT8,RGL1,DIP2A,STAC2,SUPT5H,DNMBP,PDLIM2,SMG6,PCDHB15,OBSL1,ZNF106,TMPO,CDK20,NPL,ZNF346,PPIL6,TSC1,HSPBP1,CLHC1,SGK3,PLEKHH2,MTCH1,RICTOR,MKRN3,PCBP1-AS1,MEIS3,HPS4,SIGLEC10,SLC17A7,KAT6A,RNF170" MicroRNA hsa-miR-3169:mirSVR_highEffct hsa-miR-3169:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.00E-50 1.12E-46 8.50E-50 7.82E-49 124 677 "ADD1,AXIN2,PTCHD1,PCDH19,RTL9,TAOK1,ARHGAP20,PCDH10,OGT,MYH7B,SUGT1P4-STRA6LP-CCDC180,CADPS,ASPA,ZBTB10,NUMB,ATP2A2,BACH1,DNAJC27-AS1,SYNJ1,ARHGEF7,THSD7A,PTBP2,CAST,PRC1,DLGAP1,NPIPA1,LHX2,CLCN3,RAB26,FHL5,SUMF2,CPS1,C2CD2,CREM,RNF14,CLIP3,SEC24C,ARHGEF10,VCAN,PHF14,GREB1,DOCK4,RIPOR2,ARHGAP24,LIN54,DMTF1,DPP6,AASDH,DCTN4,EPB41L2,ADGRV1,ACSL4,ZNF589,SPSB4,PRKAG2,HPCAL4,TMEM175,JKAMP,KHDRBS3,AP4B1,SULT1C4,GGTA1P,TDRKH,GRIA2,KAT7,VSIG4,SOWAHA,RBPJ,KIF5A,NCOA7,MAT2A,MATN3,MEF2C,MMP16,MXI1,MYO9A,NF1,CNOT4,PDE4D,ZNF655,ING3,MTMR10,CRTAC1,GTDC1,FIGN,ZDHHC4,NUDT11,TMLHE,YY1AP1,LRRK2,KCNIP3,KCNIP1,AP1AR,SATB1,CSRNP3,SCP2,SEC14L1,FERMT1,SHC4,FBXO11,FNDC3A,SEPHS1,CCDC88A,ATF7IP,RCOR3,TMCC1,MYO16,STAU1,RGL1,COBL,CUX2,RPGRIP1L,DOCK9,PCDHA5,ERCC6L2,BEX4,TPM1,C9orf85,ZNF711,ZFAND5,FIP1L1,MPPE1,FXR1,SENP7" MicroRNA hsa-miR-320c:TargetScan hsa-miR-320c TargetScan 2.08E-50 1.16E-46 8.79E-50 8.10E-49 117 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,CDK13,MYRF,LDLRAD4,CA12,RUNX1T1,KRIT1,CDH2,LRRFIP1,CFL2,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,AIF1L,DBN1,ARMCX2,ELMSAN1,MYEF2,DLX1,RAB39B,DMD,DTNA,CELSR3,EGR3,PLXNC1,PAN3,ETV1,NRN1,PRKAG2,MEX3B,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,ACSS1,ARFIP1,GPR75,KIAA1958,GNAL,LOXL3,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,MXI1,CNOT4,P2RX7,PCSK1,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,NXT2,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320b:TargetScan hsa-miR-320b TargetScan 2.08E-50 1.16E-46 8.79E-50 8.10E-49 117 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,CDK13,MYRF,LDLRAD4,CA12,RUNX1T1,KRIT1,CDH2,LRRFIP1,CFL2,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,AIF1L,DBN1,ARMCX2,ELMSAN1,MYEF2,DLX1,RAB39B,DMD,DTNA,CELSR3,EGR3,PLXNC1,PAN3,ETV1,NRN1,PRKAG2,MEX3B,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,ACSS1,ARFIP1,GPR75,KIAA1958,GNAL,LOXL3,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,MXI1,CNOT4,P2RX7,PCSK1,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,NXT2,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320d:TargetScan hsa-miR-320d TargetScan 2.08E-50 1.16E-46 8.79E-50 8.10E-49 117 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,CDK13,MYRF,LDLRAD4,CA12,RUNX1T1,KRIT1,CDH2,LRRFIP1,CFL2,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,AIF1L,DBN1,ARMCX2,ELMSAN1,MYEF2,DLX1,RAB39B,DMD,DTNA,CELSR3,EGR3,PLXNC1,PAN3,ETV1,NRN1,PRKAG2,MEX3B,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,ACSS1,ARFIP1,GPR75,KIAA1958,GNAL,LOXL3,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,MXI1,CNOT4,P2RX7,PCSK1,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,NXT2,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320a:TargetScan hsa-miR-320a TargetScan 2.08E-50 1.16E-46 8.79E-50 8.10E-49 117 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,CDK13,MYRF,LDLRAD4,CA12,RUNX1T1,KRIT1,CDH2,LRRFIP1,CFL2,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,AIF1L,DBN1,ARMCX2,ELMSAN1,MYEF2,DLX1,RAB39B,DMD,DTNA,CELSR3,EGR3,PLXNC1,PAN3,ETV1,NRN1,PRKAG2,MEX3B,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,ACSS1,ARFIP1,GPR75,KIAA1958,GNAL,LOXL3,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,MXI1,CNOT4,P2RX7,PCSK1,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,NXT2,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-802:PITA hsa-miR-802:PITA_TOP PITA 2.18E-50 1.22E-46 9.20E-50 8.47E-49 102 452 "FMNL2,AXIN2,PCDH19,OSBPL8,AMPD3,OGT,APC,ZBTB10,STX16,MPDZ,CAMK2A,SPAG9,CFL2,SRSF11,CHN1,LHX2,HECTD1,BAG4,ZNF521,IGDCC3,SLC35F1,CRMP1,SOCS5,DGKB,DBI,MYEF2,SNAP91,CPEB2,DMTF1,EDN1,CELSR3,MBNL2,GOLGA7,PAN3,MEX3B,STAU2,MSANTD4,OGA,GABRB3,IQGAP2,GPD2,LPAR4,CIT,PSIP1,MIER3,AGFG1,SMAP1,NKD1,TJAP1,STMN1,LIFR,MIA2,KITLG,MITF,MSI1,NEXMIF,NRCAM,PCDH9,CCSER2,PCDH18,STRN3,MINDY2,PPP3CA,PKIA,PTCH1,PTPRD,PTPRG,CEP97,TMEM255A,REV3L,FIGN,UBR7,NUDT11,ZFHX4,RTN1,SATB1,CPEB3,NLGN1,WDR37,BTBD3,SLC8A1,TMCC1,SOX11,CDK19,CLASP2,STAU1,NECAB1,ADGRL3,FBXW11,TCF4,ZFPM2,KAT6B,UBE3A,FLRT2,ZNF711,MICU3,TRIM9,ADAMTS9,NAV3,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-877*:mirSVR_highEffct hsa-miR-877*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-50 1.37E-46 1.03E-49 9.49E-49 159 1096 "CLK4,CCDC85A,BRAP,PTCHD1,TXNDC16,ZNF578,ADGRF5,PHF12,SUGT1P4-STRA6LP-CCDC180,MARCH3,PROM1,SYNJ1,ARHGEF7,CASTOR3,KALRN,PTBP2,CAST,PRC1,METTL6,CCNT1,CBFA2T2,NRXN3,CLCN3,MYL6B,CNGA3,FAM149A,IGDCC3,ENTPD4,GDA,UBXN2A,TCAF1,IP6K1,GIT2,RUSC2,TMEM130,ZC3H11A,DDX46,RHOBTB1,DMTF1,HIPK3,FRY,YAF2,ETV1,PIPOX,EXTL2,EZH1,SCML2,DLC1,ZSCAN30,FGFR3,POLK,SUCO,SEMA4D,NELFCD,WDR83,APOPT1,PDLIM5,ZNF605,DOT1L,MEGF11,TRAF3IP2,DISC1,IGSF5,GCNT2,ARFIP1,BRD8,STARD3,ZNF638,WDFY3-AS2,GPD2,STMN2,GRIA2,SPACA9,CIT,CLASRP,FAM107A,ADAMTS6,GUCY1B1,USP51,MSL1,FAM95B1,CDH20,KCNN2,CYP27C1,LIG4,LIMS1,LSS,PIK3AP1,MAT2A,MEIS1,MEIS2,AFDN,MMP16,COL28A1,MXI1,BEX5,NOVA1,DNHD1,NUCB2,PCDH9,GNG2,PFKFB3,ABCB1,TMIE,FAM216A,POLR2F,CCDC144B,PPP2R5E,CEP41,QRICH1,BDNF-AS,PTK2,TMEM260,PTPRG,MORC4,RNASEL,SETD5,CARF,CCDC102B,NEK11,NCBP3,SHC4,SLA,FAM214B,ZNF430,ZKSCAN3,RCOR3,ANKRD36,SNCA,KDM4C,PEG10,DBNDD2,RBM26,SS18,ZSCAN29,ADHFE1,FAM208A,ADGRL3,ZEB1,RNF216P1,TNS1,CDK20,TPM2,METTL3,TTC3,FLRT2,VLDLR,WIPF1,RICTOR,ZIC1,LYPD6,UPF3A,LINC02210,NAV3,FIP1L1,WNK3,MRPL47,ADAMTSL3,DPF3" MicroRNA hsa-miR-367*:mirSVR_highEffct hsa-miR-367*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-50 1.53E-46 1.16E-49 1.06E-48 140 862 "BRAP,RNF150,ZNF608,CC2D2A,PCDH10,CCDC146,SUGT1P4-STRA6LP-CCDC180,CDC14B,ARNTL,CDK13,NUMB,N4BP2L1,DPY19L3,ADAM23,SEC11C,CASTOR3,JAZF1,PTBP2,CAST,NFS1,CERS5,CD86,LRBA,CCPG1,RAB33A,C4orf33,SULT4A1,IQCK,ARMC8,SLC4A8,ABI3BP,SMARCAL1,SEC31B,RNF14,CSNK1G3,CNTNAP2,RIMS2,HDAC9,MATR3,ZBTB24,DDX46,GRIN3A,CPEB2,CASP8AP2,DNAJB6,EDNRB,PHC2,HIPK3,FSD1L,YAF2,PHF20L1,SUGP2,EGFR,C8orf37,CLVS1,ABCA8,GORAB,OGA,DENND2A,FAM120B,MTHFD2,C15orf41,TUBGCP4,ADAM28,KCNMB4,TDRKH,CCDC184,RABL2A,MAP4K5,SMAP1,ZNF546,IL6ST,HECTD2,MEIS2,SRSF12,POC1B,P2RY13,NFE2L2,DNHD1,NRCAM,NUCB2,PDE4B,OLA1,PIK3R1,RETREG1,LRP12,MINDY2,PPP2R5E,DCHS2,SAMD9,CNTLN,PTN,ZSCAN32,EML5,CEP97,SLC25A48,ZNF793,FIGN,ZDHHC4,PBRM1,ZFHX4,SETD5,ALG9,CARF,FBXW7,ATP8B4,GLDN,SALL1,GALNT10,HSPA4L,HKDC1,NLGN1,SEC31A,WDR47,RCOR3,LIMCH1,BDP1,KDM4C,ERBIN,SEPT3,ADGRL3,ZEB1,RPGRIP1L,ZFPM2,AP4E1,ERCC6L2,TPM1,AMACR,OSBP2,LAT2,ZNF45,ZNF540,LAMP5,UPF3A,PRDM8,FZD3,DOCK8,RNF170,FRMD6,SENP7" MicroRNA hsa-miR-33a-5p:TargetScan hsa-miR-33a-5p TargetScan 3.98E-50 2.23E-46 1.68E-49 1.54E-48 96 399 "ABR,CCDC85A,ADD1,BEND6,KCTD16,PCDH10,CDC42BPA,DPP10,PHF12,NCOA1,BACH1,DST,LDLRAD4,CAMK2G,RUNX1T1,DLGAP2,CLGN,CHN2,QKI,MAP4K4,AKAP12,ANKRD44,CS,SEC24C,RIMS2,CCDC144A,DCAF8,DDX46,GRIN3A,CPEB2,RCAN1,EBF1,EDNRB,CNNM1,RGS17,FGF12,FGF14,FYN,MTHFD2,GHR,RAB30,GPR37,GRM8,RNF165,LINGO1,RASSF8,HAS2,BACH2,HMGCR,SCIN,NCOA7,MEIS1,MEIS2,MMP16,NFIX,NOVA1,PDE3A,PDE4D,PDPK1,PCDH18,RFX3,ROBO2,RORB,HUNK,SALL1,CSRNP3,SCN8A,CASC3,GALNT10,CPEB3,NLGN1,FAM81A,BTBD3,CPEB4,FAM126B,HECW1,ERC1,IQSEC2,SATB2,RPGRIP1L,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RIMBP2,CSMD1,KAT6B,REEP1,CADM2,EVI5,NAV3,HNRNPA3,MSRB3" MicroRNA hsa-miR-33b-5p:TargetScan hsa-miR-33b-5p TargetScan 3.98E-50 2.23E-46 1.68E-49 1.54E-48 96 399 "ABR,CCDC85A,ADD1,BEND6,KCTD16,PCDH10,CDC42BPA,DPP10,PHF12,NCOA1,BACH1,DST,LDLRAD4,CAMK2G,RUNX1T1,DLGAP2,CLGN,CHN2,QKI,MAP4K4,AKAP12,ANKRD44,CS,SEC24C,RIMS2,CCDC144A,DCAF8,DDX46,GRIN3A,CPEB2,RCAN1,EBF1,EDNRB,CNNM1,RGS17,FGF12,FGF14,FYN,MTHFD2,GHR,RAB30,GPR37,GRM8,RNF165,LINGO1,RASSF8,HAS2,BACH2,HMGCR,SCIN,NCOA7,MEIS1,MEIS2,MMP16,NFIX,NOVA1,PDE3A,PDE4D,PDPK1,PCDH18,RFX3,ROBO2,RORB,HUNK,SALL1,CSRNP3,SCN8A,CASC3,GALNT10,CPEB3,NLGN1,FAM81A,BTBD3,CPEB4,FAM126B,HECW1,ERC1,IQSEC2,SATB2,RPGRIP1L,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RIMBP2,CSMD1,KAT6B,REEP1,CADM2,EVI5,NAV3,HNRNPA3,MSRB3" MicroRNA hsa-miR-1184:mirSVR_highEffct hsa-miR-1184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.07E-50 2.28E-46 1.71E-49 1.58E-48 145 925 "DGCR6,EMILIN3,KLHL32,TAOK1,ZNF687,MAP4K3,SUGT1P4-STRA6LP-CCDC180,LGR5,MADD,CADPS,NUMB,ADGRB3,DST,ARHGEF7,CASTOR3,PTBP2,CAMK2G,VXN,NFS1,EPS15L1,TPP1,ARMC8,LETMD1,CDC42BPB,SNCAIP,SEC24C,VCAN,PDE4DIP,APPL1,TCAF1,HDAC4,DBI,ARMCX2,JAKMIP2,RUSC2,DDX46,RHOBTB1,SACS,CHRDL1,EXOG,GRIN3A,RAB39B,DPYSL2,DUSP9,DNAJB6,ABCC5,AASDH,ANKRD46,YAF2,MBNL2,C3orf18,EPHB1,GPHN,DENND4A,ADGRV1,EYA1,FCGRT,FGF1,OLFM1,RGPD5,NELFCD,FOLH1,ATP2C1,SYT17,DISC1,TUBGCP4,ARFIP1,RAB40B,GNAO1,ZNF782,WDFY3-AS2,FUT10,PCLO,STMN2,GRIA2,PRDM5,ZBTB49,IRAK3,NKD1,ITPKB,KCNB1,KCND1,KCNN3,TTYH2,MYO7A,ZNF862,NF1,DNHD1,SETD4,ENPP2,GNG2,DRAM2,RELN,NDUFS7,BCAS3,GDPD2,PIGG,MTMR10,TMEM260,SLC25A48,FAT4,RADX,RNASEL,ELP2,ADAL,LRRK2,NCBP3,SCN7A,SUPT20H,SCAF8,ASAP3,NLGN1,SLC11A1,ATF7IP,SMARCD3,RCOR3,LIMCH1,FNBP1,ZSWIM8,HECW1,ERC1,SPTAN1,ATP10B,PHLDB1,TACR1,TBCEL,TPCN2,SYNE1,DICER1,ERCC6L2,RIMBP2,TPM1,C9orf85,RGMB,PPIL6,UBE2H,TRIM9,CELF4,SLC17A7,WNK3,PDSS2,UBE3B,SMIM8,CASC15,SENP7" MicroRNA hsa-miR-92a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-50 2.28E-46 1.71E-49 1.58E-48 182 1407 "NDRG3,TMCC3,USP31,CASKIN1,OSBPL8,CC2D2A,AK2,FAM135A,ZNF687,OGT,PHF12,ARHGDIA,ARRB1,DYNLL1,ATP1A1,ATP2A2,KIF1A,BCS1L,BID,SYNJ1,CARS,HIP1R,PRC1,ARHGEF25,CBR1,CBS,CBFA2T2,SCARB1,CHN1,PLEKHB1,TAOK2,NRXN3,CLTC,TMEM184B,HECTD1,COX4I1,LRIG1,SIPA1L1,SOCS5,PDE4DIP,APPL1,PPP6R2,ZFYVE16,EARS2,MAML1,SPOCK2,GIT2,DBT,MYEF2,KLHL3,CPEB2,PDCD6IP,RCAN1,HIPK3,OPTN,MRO,KMT5B,EIF4G2,PLEKHA1,EIF1,DNAJC27,TUBB3,SCML2,SLC37A3,FLYWCH1,CSPG5,SARAF,DOT1L,GAA,ERAP1,ZNF276,RNPS1,GLYR1,MSL3,KIAA1958,PRRC2B,FUT10,LILRA2,TPPP,DIDO1,CACFD1,CIT,SLC2A6,ATXN2L,GABARAPL2,HMGCR,AGBL5,EID2B,ZIC5,RBPJ,IL6ST,IPO5,LAMP2,PIK3AP1,MAP4,MBNL1,SHC3,MEF2C,AFDN,MYO5A,MYO6,HNRNPM,CNOT4,CCSER2,SNX10,ZFYVE21,XRN1,PKM,NLE1,PURG,TATDN3,MAPK9,MTMR10,PTPN13,CEP97,REV3L,KLHL11,SLC25A36,ZFHX4,RNH1,SETD5,RPL15,FBXW7,TRAPPC13,SAFB,ATXN7,FNIP1,SEC14L1,RASA3,SCAF8,CPEB3,SHMT2,WDR37,DHX30,KANSL3,SLC6A8,ZNF430,SLC12A4,BTBD7,ATF7IP,CPEB4,FAM126B,SOX11,MYCBP2,MCF2L2,PBLD,CAMTA2,POGZ,ITPRID2,NSFL1C,JMJD6,SUPT5H,TACC1,TBCEL,TBL1X,SIN3B,DOCK9,SIRT1,MTMR14,NACC2,CBX5,TRIO,TSC1,HSPBP1,SGK3,UBE2H,UCHL1,KLC2,CLDND1,XPO1,ZNF17,ZNF24,FTSJ1,MFF,EVI5,GDPD5,RNF103,PHTF2,RSPRY1,NHSL1,FXR1,GAN" MicroRNA hsa-miR-548b-3p:mirSVR_highEffct hsa-miR-548b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.21E-50 2.35E-46 1.77E-49 1.63E-48 148 962 "SLC24A4,BIN1,APBA2,UPRT,CPNE5,PPP4R4,ARNTL,ATP1B3,ATP6V1G2,BBS2,JAZF1,KALRN,VXN,CH25H,CBR1,LDB2,CERS5,SLC16A4,C1orf52,ZMYM4,CDO1,SOCS6,CNOT8,QKI,SRP14-AS1,AKAP6,ABI3BP,AKAP12,GDA,CCDC144A,RIPOR2,ZFYVE16,MATR3,IST1,PABPC5,ARMCX2,SPATA2,FBXL5,CHRDL1,DYNC1I1,CPEB2,RCAN1,GOLT1B,SEMA3D,PHF20L1,KMT5B,CALCRL,PAN3,STX2,DLC1,FGF13,POLK,FOLH1,EFCAB2,NBEA,UFM1,CSPG5,AP4B1,GABRG2,FAM120B,ZNF234,CPLX2,SULT1C4,ADAM28,GLUL,ZNF638,CCDC184,GRB10,RNF165,HAS2,LRRC75A,ZIC5,RBPJ,KIF5A,IPO5,STXBP5,STMN1,HECTD2,PIK3AP1,MATN2,LRP1B,KITLG,MSR1,ZNF862,CCDC13,NFE2L2,SLC11A2,SMIM11A,IGSF11,OGG1,GPR137C,PFKFB2,ZNF655,SNX10,EXOSC10,POLG,MAPK9,MASP1,SNRK,TMEM260,PEX2,PID1,TMEM255A,ZMAT4,DPF2,RET,FIGN,UBR7,SLC25A36,NUDT11,RNASEL,ROBO1,PCMTD2,RPE,SALL1,SCN7A,SMPD3,ZFP2,SYBU,EPN2,WDR47,SLC6A11,KDM4D,SEPHS1,RCOR3,SNCA,TSPYL2,RBM26,LARP4,NSFL1C,VPS13A,PLCB1,SYN2,SYPL1,ANKRD12,FAM208A,DMXL2,PUM2,GPRIN3,TMEM9,FAM124A,TSN,RPL7L1,UBE2H,USP1,DHX33,EMSY,FAM219B" MicroRNA hsa-miR-582-5p:PITA hsa-miR-582-5p:PITA_TOP PITA 4.48E-50 2.51E-46 1.88E-49 1.73E-48 111 544 "NDRG2,MAP4K3,APC,TMEFF1,ZBTB10,RASL11B,MTMR2,LDLRAD4,SPAG9,RUNX1T1,USP6,ZMYM4,CDO1,CCPG1,CACNA2D2,QKI,CNN3,CNR1,SOCS5,PUM1,DOCK4,MAML1,PABPC5,BRINP1,ZNF804A,MFAP3L,ALKBH8,SPOCK3,DMD,SLC29A4,NR1D2,CDON,APH1A,EIF4G2,TENM1,ETV1,MEX3B,STAU2,OGA,GATM,TNRC6A,MAP7D2,FERMT2,GPR34,ELOVL5,HMGCR,HNF4G,NEGR1,INSM1,MAP2,MARK1,MEIS1,MITF,ZC3H12B,NFE2L2,NOVA1,PDE4D,GPR85,PIK3C2A,CCSER2,RETREG1,PMP22,STRN3,SCHIP1,EPB41L4B,MAPK10,RELN,PTK2,TMEM255A,SLC25A36,PBRM1,ZFHX4,ZNF532,ROBO2,AMBRA1,FBXO11,FAM81A,WDR47,SMARCA4,TSPYL2,CLASP2,SST,LARP4,SS18,SULF2,ZC3H4,ANKRD12,CAMTA1,ADGRL3,AGTPBP1,TCF4,TCF12,PUM2,FRYL,SLC44A1,RIMBP2,CSMD1,KAT6B,SSBP2,FAM155A,UBE3A,ZIC1,TRIM9,ZFAND5,EMSY,NAV3,FZD3,RTN4,HNRNPA3,MSRB3,FRMD6" MicroRNA "TTGCCAA,MIR-182:MSigDB" "TTGCCAA,MIR-182:MSigDB" MSigDB 6.31E-50 3.53E-46 2.65E-49 2.44E-48 85 306 "ADCY6,PDZD4,OGT,ANK2,ARHGDIA,NUMB,ATP1B3,ATP2A2,ARHGEF7,JAZF1,SEPT7,MAGI1,FOXN3,QKI,AKAP7,BAG4,CLOCK,PREPL,C2CD2,CSNK1E,MYADM,IP6K1,GIT2,ELMO1,RHOBTB1,PLPPR4,EDNRB,YAF2,MBNL2,EGR3,EIF5,RGS17,EPHB1,SLC43A2,NCALD,FOXF2,FOXO3,KHDRBS3,GABBR1,SEPT9,PCDH17,KDM2B,ATOH8,BACH2,KTN1,L1CAM,SMAD1,MARK3,MEF2C,MEIS2,MITF,MMP16,NPTX1,NRCAM,OCRL,PCDH8,GPR85,RETREG1,PCDH18,PRKACB,RDX,RET,FBXW7,MCMBP,ATAT1,PPM1E,SHC4,WDR47,TEX2,NFASC,SYPL1,TACC1,CAMTA1,FBXW11,SATB2,DOCK9,RIMBP2,BCL2L13,VLDLR,EVI5,STOX2,EPM2A,FZD3,RTN4,FXR1" MicroRNA hsa-miR-296-5p:mirSVR_lowEffct hsa-miR-296-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.27E-50 4.63E-46 3.47E-49 3.19E-48 152 1017 "DGCR6,ASPHD1,SYN3,ACTN1,ADD2,UNC5A,KIAA1211,ADRA1D,TAOK1,LTBP4,BIN1,PHYHD1,PPFIA3,SPTBN4,ASGR1,TTLL9,ADGRB2,LINC00847,KSR1,BMP7,GPC2,CACNB4,LDB2,ARHGEF1,ARHGEF2,LARGE1,NOG,PPT2,STOML1,CLTB,TMEM184B,CNGA3,ARHGEF6,TOGARAM2,ZNF521,IGDCC3,CLIP3,TRIM69,CSF1,CSNK1E,CST3,ARHGEF4,DBN1,SV2B,SGSM2,FAM107B,KIF19,DMPK,MED12,DPH1,DPYSL2,TOM1,EDNRB,HEYL,CERCAM,HSD17B14,MFSD10,COQ7,EPHB1,SPEG,DLC1,FGF11,FGFR1,FGFR3,APOPT1,HHIPL1,INPP5K,GCK,ALDH1L1,CYP46A1,CRCP,GLYR1,POLL,LUZP2,GPD1,LILRA2,LINGO1,RNFT2,GUCY1A1,ATOH8,ATXN2L,ELOVL5,LRRC75A,C2orf72,KNDC1,ITPKB,KCNK3,CLEC18A,MAP4,MATK,MMP16,MPP2,PTOV1,NNAT,NME4,TBC1D25,PFKFB4,KCTD15,MBOAT7,POLR2F,GRAMD1C,MASP1,WDR25,NKAIN1,RAD51D,RASGRF1,ZDHHC4,RGS3,ARMC5,EPHA10,MEG3,HSD11B1L,SCN2B,HES6,ZNF821,GALNT10,MRAS,SLC2A5,SLC6A8,OGDHL,MAPKBP1,ZSWIM8,TSPYL2,ITPRID2,SSPO,MPRIP,SEPT8,SUPT5H,ARHGEF9,COBL,TACR1,TAL1,SMG6,WSCD1,USP22,HIF3A,SLC44A1,PIK3R5,TPM2,WBP2,TRO,TRPM2,MGAT5B,MTCH1,LAT2,CFAP298,ZNF213,SLC30A3,ITM2C,PCBP4,ADAMTS10,LAS1L" MicroRNA hsa-miR-627:mirSVR_highEffct hsa-miR-627:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.35E-50 4.67E-46 3.50E-49 3.22E-48 143 906 "ABHD6,GALNT13,PLEKHH1,INTS2,SPARCL1,ALCAM,ABCD2,AMT,EP400,SUGT1P4-STRA6LP-CCDC180,APBA2,PPP4R4,SLC2A11,ADAM23,SCAPER,KALRN,SPAG9,NFS1,CBR1,ZNF501,CLDN10,CERS5,CD38,TAOK2,RAB33A,AKAP7,LETMD1,AKAP5,SLC4A8,BAG4,TOGARAM2,ENTPD4,HAPLN1,HINFP,CS,PHF14,TBC1D5,SGSM2,NYAP1,DNAJB6,GOLT1B,HIPK3,SEMA3D,KLHL5,FSD1L,EGFR,RGS17,EPB41,EPHB1,DENND4A,CDKL3,ST3GAL6,ZSCAN30,SPSB4,SEC23B,SLC37A3,SDCBP2,B4GALNT1,ERAP1,MTHFD2,TNRC6A,MSL3,DCLK2,PCLO,SOX21,PSIP1,PADI2,TNFAIP8L3,EID2B,ZIC5,C2CD4C,KCNB1,KIT,CYP27C1,LIMS1,ASPRV1,MAN2A2,MARK1,MAT2A,AQP11,EFHB,COL28A1,NCAM2,NFYA,NOVA1,DNHD1,CNTN3,PDCD2,PIK3C2A,ZNF655,SEPT4,SH3KBP1,KANSL1,RASGEF1B,GDPD2,CNTLN,EML5,PTPRE,SH3TC2,FAT4,RAP1GDS1,KLHL11,SETD5,GSTCD,NEK11,RPL15,SEC14L1,SHMT2,CNKSR2,SLA,PPP4R3A,BTBD3,SNAP25,SNRPN,SEPT3,KLHL7,SYN2,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,BHLHB9,ERCC6L2,RGMB,TSC1,RPL7L1,EIF4ENIF1,OSBP2,ZNF781,CLDND1,TRIM9,MKRN3,FIP1L1,FAM13C,MARCH8,PHTF2,JMJD1C,RNF146" MicroRNA hsa-miR-220c:mirSVR_highEffct hsa-miR-220c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.42E-50 4.71E-46 3.52E-49 3.24E-48 132 776 "CLK4,KCTD16,AK2,FAM135A,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,CDK10,CHID1,ATP2A2,ATP6V1G2,ADAM23,LINC00847,ZNF599,CFL2,SRSF11,SOCS6,CHN2,CNGA3,AKAP6,COL4A5,MAGED1,ENTPD4,ANKRD44,GDA,RGS6,VAC14-AS1,SLITRK5,PUM1,DAPK1,RHOBTB1,HS3ST2,USP3,CPEB2,DPP6,ARRDC4,AASDH,EDIL3,EDNRB,RASGRP1,SEMA3D,PAN3,F8,ZSCAN30,POLR1B,FHL1,IP6K2,DCTN2,GABBR1,GALC,ERAP1,SIGLEC8,TUBA8,ADAM28,DHRS4,GPD1,FUT10,FAM19A2,ADAMTS6,MIER3,RBPJ,ZNF678,ITGA7,MAN2A2,KCTD6,PPM1L,MYO7A,NPY,SMIM11A,NUCB2,IGSF11,GLIPR1L2,PDE4B,PFKFB2,PLXNB1,SEPT4,KANSL1,BCAS3,PTCH1,PTPRG,FAM184A,RAP1GDS1,RBBP6,RIC8B,ZFHX4,ROBO1,LRRK2,NCBP3,FBXO11,ST8SIA1,KANSL3,SLC6A8,KDM4D,SLC9A5,SLC22A4,TET1,SMARCD3,TTC17,INAVA,SNAP25,MAPKBP1,HECW1,MCF2L2,POGZ,SS18,NSFL1C,ARHGEF9,SYN2,TACR1,KLHL4,DMXL2,ZEB1,SLC19A3,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ANKRD24,ZNF346,SMUG1,MKRN3,MAP3K12,FAM47E,EPM2A,UBE3B,KAT6A,SMIM8" MicroRNA hsa-miR-520g:PITA hsa-miR-520g:PITA_TOP PITA 8.46E-50 4.73E-46 3.54E-49 3.26E-48 107 507 "USP31,SLC24A4,ZNF608,PCDH19,OSBPL6,PARG,APBB2,STK33,MARK4,EIF4G3,ATP2B2,ADGRB2,JAZF1,DLGAP2,CFL2,SOCS6,PCYT1B,ZNF385A,PPP6R2,RUBCN,DCAF8,IP6K1,DBN1,TIAM2,RHOBTB1,GRIN3A,RAB39B,DMD,USP3,DMTF1,DNAJB6,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,EIF5,EPB41,ERBB2,ERBB4,PTK2B,SCML2,FGF12,FOXF2,NBEA,MSANTD4,OGA,RUNDC3A,TCERG1,TNRC6A,CIT,LINGO1,ITPKB,MAT2A,MBNL1,CHIC1,MID1,XRRA1,MXI1,MYCN,ZC3H12B,NPTX1,GPR137C,CNTN3,PPP3CA,MAPK9,PTPN13,SLC25A36,KCNIP1,RYR3,SALL1,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLA,FAM126B,SOX11,ITPRID2,SEPT8,RGL1,SYNE2,PLCB1,FBXW11,TBL1X,TCF4,SATB2,TCF12,PUM2,THRA,HEY1,TPM1,NR2C2,PDSS1,TRPS1,FLRT2,PLEKHH2,VLDLR,TBC1D15,REEP1,DPYSL5,SLC30A3,EMSY,ADAMTSL3,FRMD6,DPF3" MicroRNA hsa-miR-520h:PITA hsa-miR-520h:PITA_TOP PITA 8.46E-50 4.73E-46 3.54E-49 3.26E-48 107 507 "USP31,SLC24A4,ZNF608,PCDH19,OSBPL6,PARG,APBB2,STK33,MARK4,EIF4G3,ATP2B2,ADGRB2,JAZF1,DLGAP2,CFL2,SOCS6,PCYT1B,ZNF385A,PPP6R2,RUBCN,DCAF8,IP6K1,DBN1,TIAM2,RHOBTB1,GRIN3A,RAB39B,DMD,USP3,DMTF1,DNAJB6,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,EIF5,EPB41,ERBB2,ERBB4,PTK2B,SCML2,FGF12,FOXF2,NBEA,MSANTD4,OGA,RUNDC3A,TCERG1,TNRC6A,CIT,LINGO1,ITPKB,MAT2A,MBNL1,CHIC1,MID1,XRRA1,MXI1,MYCN,ZC3H12B,NPTX1,GPR137C,CNTN3,PPP3CA,MAPK9,PTPN13,SLC25A36,KCNIP1,RYR3,SALL1,FAM102A,CPEB3,CHD9,FNDC3A,WDR37,SLA,FAM126B,SOX11,ITPRID2,SEPT8,RGL1,SYNE2,PLCB1,FBXW11,TBL1X,TCF4,SATB2,TCF12,PUM2,THRA,HEY1,TPM1,NR2C2,PDSS1,TRPS1,FLRT2,PLEKHH2,VLDLR,TBC1D15,REEP1,DPYSL5,SLC30A3,EMSY,ADAMTSL3,FRMD6,DPF3" MicroRNA hsa-miR-658:mirSVR_lowEffct hsa-miR-658:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.72E-50 4.88E-46 3.64E-49 3.35E-48 153 1030 "ACHE,ADD1,ADD2,ESYT2,AMPD3,CCDC146,PHF12,PKP4,SFMBT2,LINC00173,MARK4,SLC2A11,LINC00847,CFAP410,CA12,CALB2,CALM1,SCARB1,MAGI1,CNOT8,TAOK2,EPS15L1,NRXN3,PPT2,IQCK,FAM149A,CABP1,SLC35F1,CRY2,CSF2RA,CSNK1E,PPP1R16B,UBXN2A,RUBCN,MYADM,DCAF8,MYEF2,C2CD2L,GUCD1,RHOBTB1,USP3,DPH1,DTNB,DNM1L,FCF1,MBNL2,TMEM132E,ENO2,MFSD10,RABEPK,SLC43A2,ERBB2,ERCC2,CLVS1,ZNF461,TUBB3,CHST15,STRADA,ZNF589,FER,FHL1,NOP56,CELF1,ABLIM2,INPP5K,GPR162,GGT5,RAB30,GP1BB,SPACA9,LINC01089,ZBTB49,FAM107A,RNFT2,LRRC25,INSM1,SFXN5,CLEC18A,MAN2A2,MYO7A,NINJ2,OGG1,PCSK5,PRTG,OLA1,ZDHHC8,NALCN,FAM216A,PURG,MAPKAP1,FA2H,TMEM104,RIPOR1,PID1,UBR7,RGS3,RGS12,RNASEL,ALG9,PNMA8A,KIAA0895L,MEG3,NCBP3,S100B,SCP2,FBXO11,PEX26,DHX30,LIMS2,SLC6A8,SMARCC2,RCOR3,SNRPN,FAM219A,BDP1,FNBP1,ZSWIM8,KDM4C,SPTB,NFASC,NKAIN2,SS18,STAU1,SEPT8,KANK1,SYN1,SYP,IQCE,MGRN1,DMXL2,CUX2,TPCN2,PCDHB9,USP32P1,ARHGAP9,SIK3,RASD2,C9orf85,TSC2,UBTF,BCL2L13,LGI4,ZNF24,ZNF28,TRIM9,ZFP41,ATP6V0E2,DNALI1,HPS4,CIAPIN1,WNK3,DOCK8,ST7" MicroRNA hsa-miR-3134:mirSVR_highEffct hsa-miR-3134:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.00E-49 5.60E-46 4.18E-49 3.85E-48 135 812 "KCNH8,XKR4,FMNL2,KIAA1211,HECW2,PCDH19,RTL9,ARHGAP20,FAM135A,SUGT1P4-STRA6LP-CCDC180,PHYHD1,PPP4R4,CADPS,DYNLL1,ZNF583,ADAM23,BCL7A,ZNF599,CFLAR,CAST,CCNH,MTMR7,SRSF11,CHN2,ARHGEF6,LETMD1,COL9A3,RCHY1,RTTN,LRIG1,LRRC3B,KIAA0408,DOCK4,MYADM,ZNF337,GIT2,ZC3H11A,RHOBTB1,FAM107B,GRIN3A,RAB39B,DTNA,DNM1L,ANKRD46,PHF20L1,SUGP2,EIF1,IGSF6,ETV1,STRADA,SLC9B2,POLR1B,SEMA4D,FLT1,SMC2,ATP2C1,ST6GALNAC3,DOT1L,ERAP1,MSTN,PCDH17,TNRC6A,KCNMB4,GPD2,FUT10,GRIA2,FAM222A,VSIG4,MSL1,LRRCC1,KIAA1755,IL12A,KIF5A,HECTD2,MAN2A2,TM6SF1,ADAM22,MSR1,MYT1,P2RY13,NF1,GLIPR1L2,PCDH9,SNX10,MTRF1L,STRN3,NECAB2,MAGEL2,ING3,EPB41L4B,PPARA,PPP2R5E,GRAMD1C,TMEM260,PTPRH,C1orf109,ZNF615,RNASEL,ZNF532,TMLHE,NCBP3,LRFN5,SCP2,ZFP2,KIF16B,NLGN1,PREX2,KBTBD4,ELMO2,CPEB4,MAST1,SNCA,SNRPN,MYO16,HECW1,NFASC,ATP10B,SSTR1,SSTR2,NKAIN2,TAL1,C18orf54,ERCC6L2,KAT6B,SSBP2,CLDND1,PCDH20,ZNF28,TRIM9,FSTL5,ANKS1B,MEIS3,MDH1B,JMJD1C,RNF170" MicroRNA hsa-miR-323b-3p:mirSVR_highEffct hsa-miR-323b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-49 5.97E-46 4.45E-49 4.09E-48 115 590 "CLK4,KLHL13,TXNDC16,LRCH2,DST,SYNJ1,FUBP1,GPC2,IL33,USP6,CHN1,CHN2,QKI,COL9A1,SLC4A8,ABI3BP,AHCTF1,RTTN,ZFP28,NECTIN3,GDA,CSF1,OSBPL3,VCAN,DOCK4,ZFYVE16,BRINP1,HEPH,SV2B,SPOCK3,CHRDL1,GRIN3A,DMD,CPEB2,ECM2,E2F5,SNX29,EIF4G2,TENM1,FAM198B,SCML2,FER,FGFR3,SUCO,PSD2,NBEA,TMEM107,PDLIM5,CELF1,OGA,GABRG2,DISC1,NEU3,MSTN,RUNDC3A,COPS8,RAB40B,FERMT2,GPR37,KAT7,NME9,METTL21A,STXBP5,STMN1,MBNL1,KCTD6,MITF,ZNF92,CNOT4,NOVA1,NPTX2,GPR85,OLA1,NALCN,PKD1,PMP22,ING3,PPP3CA,PPP3CC,DIRAS2,ACSM5,USP47,TRIM68,UBR7,MRPS18A,EXD2,ABCA11P,SAFB,CPEB3,FBXO11,NAPB,ZFP1,SNCA,CABCOCO1,SNRPN,PDZD2,BDP1,ZC4H2,ERBIN,VPS13A,FAM208A,AGTPBP1,DOCK9,PUM2,USP32P1,SLC44A1,LRRC8A,METTL3,NEIL2,CLEC2L,MTCH1,VSNL1,ZNF189,UPF3A,RNF103" MicroRNA hsa-miR-199a-5p:TargetScan hsa-miR-199a-5p TargetScan 1.18E-49 6.62E-46 4.92E-49 4.53E-48 98 422 "RALGAPA1,ACHE,PLEKHH1,ARHGAP20,MAP4K3,MARK4,ATP2B2,BCL7A,DST,MTMR3,MYRF,CA12,DDR1,CABP7,HIP1R,RUNX1T1,CDH2,CHN2,CLCN3,CLTC,CLOCK,PREPL,HAPLN1,NCOR1,SEC24C,FAM169A,KIAA0040,RASSF2,IST1,MYEF2,KIAA0753,KLHL3,SACS,FAM107B,ABCC5,E2F6,PLXNC1,RGS17,PAN3,RAB9B,ERBB4,CEP85L,REEP2,DLC1,FER,PCYOX1,NSG1,FUT9,GCNT2,PCDH17,CSDC2,PPARGC1A,KIAA1958,GPD2,GRB10,PRDM5,HAS2,MIER3,HLF,METTL21A,KLHL23,KIT,PAXBP1,MAP2,AQP11,MATN2,MGAT3,PPM1L,MN1,GIT1,MYO5A,NBL1,NFYA,P2RX7,PDE4D,PLXNB1,PMP22,FSD1,PPM1B,MAPK4,FIGN,RFX3,PBRM1,RORB,CLIP1,ATXN7,BTBD3,MBD5,FAM126B,LARP4,CBX5,R3HDM1,RGMB,MARCH8,PHTF2,ADAMTSL3,FXR1,JPH3" MicroRNA hsa-miR-199b-5p:TargetScan hsa-miR-199b-5p TargetScan 1.18E-49 6.62E-46 4.92E-49 4.53E-48 98 422 "RALGAPA1,ACHE,PLEKHH1,ARHGAP20,MAP4K3,MARK4,ATP2B2,BCL7A,DST,MTMR3,MYRF,CA12,DDR1,CABP7,HIP1R,RUNX1T1,CDH2,CHN2,CLCN3,CLTC,CLOCK,PREPL,HAPLN1,NCOR1,SEC24C,FAM169A,KIAA0040,RASSF2,IST1,MYEF2,KIAA0753,KLHL3,SACS,FAM107B,ABCC5,E2F6,PLXNC1,RGS17,PAN3,RAB9B,ERBB4,CEP85L,REEP2,DLC1,FER,PCYOX1,NSG1,FUT9,GCNT2,PCDH17,CSDC2,PPARGC1A,KIAA1958,GPD2,GRB10,PRDM5,HAS2,MIER3,HLF,METTL21A,KLHL23,KIT,PAXBP1,MAP2,AQP11,MATN2,MGAT3,PPM1L,MN1,GIT1,MYO5A,NBL1,NFYA,P2RX7,PDE4D,PLXNB1,PMP22,FSD1,PPM1B,MAPK4,FIGN,RFX3,PBRM1,RORB,CLIP1,ATXN7,BTBD3,MBD5,FAM126B,LARP4,CBX5,R3HDM1,RGMB,MARCH8,PHTF2,ADAMTSL3,FXR1,JPH3" MicroRNA hsa-miR-768-3p:PITA hsa-miR-768-3p:PITA_TOP PITA 1.20E-49 6.71E-46 4.99E-49 4.59E-48 91 359 "KIAA1324,SPOP,LCORL,ARNTL,SLC4A4,RNF182,FUBP1,JAZF1,PTBP2,USP6,ZMYM4,FOXN3,HOMER3,BAG4,RIMS4,APPL1,PLCXD3,RIMS2,ARHGAP24,LONRF1,YTHDC1,SNAP91,GRIN3A,CDON,DNAJB6,KLHL5,EIF4G2,AFF2,FUT9,GATM,MSTN,SESN1,PCDH17,SPIN1,TMEM121B,PCLO,PSIP1,ADAMTS6,BACH2,NEGR1,AGFG1,ZIC5,STXBP5,MID1,MYCN,NEXMIF,PCDH8,PCDH9,PDE4B,SERPINI1,RELN,SNRK,OXR1,REV3L,ZFHX4,SETD5,ROBO2,NCBP3,SEMA6D,SCN8A,CASC3,PPM1E,CPEB3,AMBRA1,NLGN1,SEPHS1,SLC12A2,SLC12A4,TET1,SNAP25,FAM126B,MYCBP2,CLASP2,POGZ,LARP4,NKAIN2,STXBP1,ADGRL3,RPGRIP1L,DOCK9,PUM2,RIMBP2,NR2C2,TSN,FAM155A,XRCC4,RGS7BP,RTN4,NETO2,DPF3,RNF146" MicroRNA hsa-miR-663:mirSVR_lowEffct hsa-miR-663:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-49 1.01E-45 7.47E-49 6.87E-48 135 816 "ACHE,CLK4,ADORA1,OLMALINC,AP2A2,LTBP4,AMPD2,PHF12,NT5C3B,PPFIA3,CDC14B,CDK10,PRX,MADD,ARRB2,LINC00173,ADAM15,ADGRB2,KSR1,PTBP2,RHBDL1,SLC16A4,ARHGEF1,ENTPD2,CDC25B,KCNAB3,DLGAP1,CCPG1,CACNA2D2,ASIC3,TAOK2,EPS15L1,PPT2,IQCK,ZNF385A,NCOR2,CSF1,PITPNM3,KIAA0040,DBN1,DNM1,NYAP1,TNK2,MFSD10,MTSS1L,RABEPK,RASL12,DLC1,FCGRT,FDFT1,OLFM1,FGF11,AGAP2,FLT1,ERGIC3,DOT1L,GHDC,INPP5K,ALDH1L1,TUBA8,GLYR1,GPD1,GPER1,GRIN2C,GRIN2D,PACSIN2,ATXN2L,LRRC75A,IRF8,FAM95B1,MYLK2,C2CD4C,GATD1,KIFC3,LINC00634,XRRA1,RTL5,SETD4,PALM,NLE1,FXYD1,MTRF1L,PILRA,PPP5C,VSTM2L,SUSD4,RASGRF2,RFX2,SNX22,ATAT1,CLIP1,SH3GL3,ST6GAL1,ABLIM3,FAM81A,MAPKBP1,SP2,IQSEC2,MCF2L2,STX1A,SYN2,SATB2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,CDH22,GALNT17,TIAM1,RELL2,LRRC8A,RASD2,IL34,WBP2,ELP5,AMACR,TTTY15,TOM1L2,VLDLR,LMF1,KCNK12,ZIC2,ZNF19,ATP6V0E2,ZNF70,SPHK2,DPYSL5,WNK2,JPH3" MicroRNA hsa-miR-767-3p:mirSVR_highEffct hsa-miR-767-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.95E-49 1.09E-45 8.10E-49 7.45E-48 141 888 "XKR4,ADCY6,ADD1,PWWP2A,RTL9,NME5,PPFIA4,PHYHD1,PPP4R4,CHRD,STX16,N4BP2L1,ADAM23,ZNF599,CFLAR,DST,SGCE,THSD7A,PTBP2,CAMK2G,CBR1,CD86,SRSF11,CNOT8,RAB33A,SULT4A1,IGLON5,CNR1,COL4A5,SLC4A8,RBM39,PDE4DIP,DOCK4,HDAC9,DGKG,TMEM170A,TIAM2,FBXL5,SV2B,EXOG,CDON,PDCD6IP,ABCC5,HIPK3,OPTN,EGFR,GOLGA7,EPB41L2,SIRPB1,GMPR2,FAM198B,FDFT1,ZNF589,GTF2IRD2,BAIAP2,POLK,ANKFY1,SLC37A3,COQ5,CINP,SMC2,GHDC,MTHFD2,KDM2B,GPD2,GRM8,RABL2A,NCKAP1L,KIF2A,MAN2A2,ZFYVE27,MN1,ZNF680,BLOC1S2,MXI1,NEFH,NEK1,SMIM7,EPB41L4B,PPM1B,VSTM2L,GRAMD1C,SNRK,PIGG,PTCH1,ZIK1,TMEM255A,RADX,SLC25A36,RNASEL,CARF,CCDC102B,RPE,NEK11,ARMH4,BAALC,ABCA11P,ZNF568,ZNF331,DGLUCY,SCN8A,CPEB3,SEC31A,CCDC88A,ZFP1,IFT122,SNCA,HECW1,KDM4C,ZC3H13,DBNDD2,DDN,ZNF302,SSTR2,NEK4,ADHFE1,PRRC2C,SYNE2,VPS13A,CAMTA1,ZEB1,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TK2,KAT6B,PPIL6,VLDLR,TBC1D15,GUSBP1,ZNF138,UPF3A,PRDM10,TUBA1A,IFT88" MicroRNA hsa-miR-107:TargetScan hsa-miR-107 TargetScan 2.41E-49 1.35E-45 1.00E-48 9.21E-48 114 584 "ABCF1,ASIC1,GALNT13,RNF157,ADD1,AXIN2,OSBPL6,AK2,OGT,CASK,PDE8B,MARCH3,FUBP1,MTMR3,CACNA2D1,CAMK2G,RUNX1T1,ARMC8,LETMD1,CLOCK,ENTPD4,AKAP12,CSNK1G3,APPL1,PPP6R2,LONRF1,MAML1,GIT2,JAKMIP2,DYNC1I1,NR1D2,RCAN1,EBF1,EDIL3,MBNL2,EIF5,PLEKHA1,RGS17,CEP85L,CORO2B,ANKFY1,CINP,NSG1,GABRG2,DISC1,PCDH17,RAB30,KIAA1958,GNAO1,FERMT2,GPR12,ADAP1,KAT7,RASSF8,BACH2,HLF,AGFG1,KCND1,KCNN3,KIF5A,MAP4,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,MYCN,NF1,NOVA1,NOVA2,PDE3A,PDE4D,ENPP2,PIK3R1,PRKAB2,PKIA,CNNM2,EML5,PPP2R3C,FAT4,RBBP6,PRRT2,RGS4,ALG9,GSTCD,RORB,FBXW7,CLIP1,SALL1,ATXN7,SCN8A,COPZ1,SCAF8,KIF21A,PPM1E,CPEB3,FAM81A,MAPKBP1,FAM126B,PEG10,LHPP,PLCB1,MMS19,SATB2,RPGRIP1L,GPRIN3,FRYL,DICER1,NR2C2,BCL2L13,KCNK12,ADAMTSL3,GAN,JPH3" MicroRNA hsa-miR-103a-3p:TargetScan hsa-miR-103a-3p TargetScan 2.41E-49 1.35E-45 1.00E-48 9.21E-48 114 584 "ABCF1,ASIC1,GALNT13,RNF157,ADD1,AXIN2,OSBPL6,AK2,OGT,CASK,PDE8B,MARCH3,FUBP1,MTMR3,CACNA2D1,CAMK2G,RUNX1T1,ARMC8,LETMD1,CLOCK,ENTPD4,AKAP12,CSNK1G3,APPL1,PPP6R2,LONRF1,MAML1,GIT2,JAKMIP2,DYNC1I1,NR1D2,RCAN1,EBF1,EDIL3,MBNL2,EIF5,PLEKHA1,RGS17,CEP85L,CORO2B,ANKFY1,CINP,NSG1,GABRG2,DISC1,PCDH17,RAB30,KIAA1958,GNAO1,FERMT2,GPR12,ADAP1,KAT7,RASSF8,BACH2,HLF,AGFG1,KCND1,KCNN3,KIF5A,MAP4,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,MYCN,NF1,NOVA1,NOVA2,PDE3A,PDE4D,ENPP2,PIK3R1,PRKAB2,PKIA,CNNM2,EML5,PPP2R3C,FAT4,RBBP6,PRRT2,RGS4,ALG9,GSTCD,RORB,FBXW7,CLIP1,SALL1,ATXN7,SCN8A,COPZ1,SCAF8,KIF21A,PPM1E,CPEB3,FAM81A,MAPKBP1,FAM126B,PEG10,LHPP,PLCB1,MMS19,SATB2,RPGRIP1L,GPRIN3,FRYL,DICER1,NR2C2,BCL2L13,KCNK12,ADAMTSL3,GAN,JPH3" MicroRNA hsa-miR-17-5p:Functional MTI Functional MTI miRTarbase 2.60E-49 1.45E-45 1.08E-48 9.90E-48 164 1181 "RALGAPA1,FMNL2,ADD1,FZD9,SORCS2,ZNF578,MARCH4,SEMA7A,EPB41L5,EIF4G3,ATP1B3,KIF1A,LDHD,ARHGEF7,MTMR3,ZBED1,DIS3L,CFL2,SOCS6,EPS15L1,QKI,RTTN,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,SOCS5,UBXN2A,DCAF8,EARS2,DAPK3,DNAL1,YTHDC1,ELMSAN1,FBXL5,SACS,SEC16A,USP3,MED12,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,OPTN,KMT5B,EIF4G2,IRAK4,CERCAM,EPB41L2,ERCC2,ETV1,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,FER,GTF2IRD2,POLR1B,SUCO,ANKFY1,ZBED3,PDLIM5,TPK1,OGA,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,FUT10,CIT,FICD,HAS2,ITPKB,KCNB1,CAMK2N2,GPR155,MBNL1,CHIC1,SCAMP5,AFF1,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,CCSER2,ZFYVE21,TMEM38A,ZNF426,MTRF1L,LRP12,KANSL1,PRKACB,PRKCB,MAPK9,VPS13C,ZIK1,PTPRO,CEP97,OXR1,ZNF532,ELP2,ATAT1,ATXN7,TMEM200C,TRA2B,HSPA4L,FAM102A,CHD9,WDR37,ELMO2,BTBD7,COA1,CMTR2,FAM126B,SP2,SP4,MYCBP2,POGZ,STAC2,ANKRD12,CAMTA1,DNMBP,TCF4,GPRIN3,ZMAT3,AKTIP,TMEM9,NACC2,CBX5,PARD3,RGMB,NR2C2,TSC2,UBC,VLDLR,TBC1D15,ZNF70,SH3GLB2,DHX33,MAP3K12,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2,RNF146,LAS1L" MicroRNA hsa-miR-539:PITA hsa-miR-539:PITA_TOP PITA 2.66E-49 1.49E-45 1.10E-48 1.01E-47 104 483 "ACTN1,NDRG3,ADRA1B,PCDH19,SPOP,FAM135A,AMPH,ZBTB10,NCOA1,CCAR2,ATP2A2,BCL7A,RUNX1T1,ZMYM4,CACNA2D2,CFL2,FOXN3,CNN3,CNR1,CNTFR,ZNF521,SEC24C,SOCS5,SLITRK5,IP6K1,DBT,KLHL3,YAF2,APH1A,TENM1,TMEM35A,PAN3,RCAN2,EPHB1,ERBB4,ETV1,NRN1,F5,SCML2,FGF13,PRKAG2,FOXO3,FYN,MEGF11,MMADHC,PPARGC1A,RAB30,TOX3,GNAO1,GRIA2,RNF165,KAT7,BACH2,KCND2,SFXN5,MAP2,CHIC1,MITF,HS6ST3,NEXMIF,TCEAL5,NELL2,NPTX1,NLGN3,NALCN,XRN1,PDZRN4,RANBP3L,ELOVL2,PTK2,PRRT2,FIGN,ZFHX4,ZNF532,FNIP1,PPM1E,CHD9,R3HDM2,PKNOX2,TET1,SNCA,FAM126B,SOX11,ARHGAP26,ZBTB43,CLASP2,LARP4,STAU1,SYN1,FBXW11,TCF4,TRIM2,RPGRIP1L,TCF12,PUM2,ZFPM2,CBX5,RPRM,FAM155A,UBE2H,ZIC1,SMARCAD1,SLC30A4,CADM2" MicroRNA hsa-miR-610:mirSVR_highEffct hsa-miR-610:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-49 1.52E-45 1.12E-48 1.03E-47 125 704 "ACADM,ESYT2,HACE1,LCORL,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,MARCH3,ATP2A2,BMP7,ST3GAL5,KALRN,RUNX1T1,CBR1,NUMBL,MS4A7,NDST3,FAM19A5,CNTN1,COL4A5,SLC4A8,SMARCAL1,HINFP,ANKRD44,GDA,CSNK1G3,PUM1,LIN54,DGKB,PABPC5,DBN1,FBXL5,ALKBH8,DMD,EBF1,FCF1,RASGRP1,FSD1L,PLEKHA1,PAN3,SRRM1,DENND4A,MRPL37,MRVI1,HSPA12B,DLC1,SLC9B2,FGF14,FGFR1,SUCO,JKAMP,NSG1,MSANTD4,SARAF,AP4B1,OGA,ERAP1,MALT1,MAP7D2,GRM8,CIT,GUCY1B1,RASSF8,ELOVL5,HNF4G,SCIN,INPP5B,CREG2,SMAD1,PIK3AP1,MEIS1,KITLG,XRRA1,COL28A1,NFE2L2,NUCB2,ETFRF1,PDE4D,MTRF1L,PRIMPOL,MBOAT7,RASGEF1B,MAPK9,GRAMD1C,VPS13C,QRICH1,PIGG,CNTLN,PTPRD,ACSM5,MARCH1,RET,LGI2,ROBO2,SAFB,SCP2,RASA3,SHC4,ABLIM3,SLC12A2,RCOR3,SNRPN,USP33,NMNAT2,NKAIN2,STXBP1,KLHL7,NECAB1,FAM208A,TCEA1,ZFP90,TLR4,TMPO,CSMD1,KAT6B,ANKRD20A2,CCDC14,CLDND1,CFAP298,DHX33,WNK3,RGS7BP,PHTF2,NLRP3,NETO2" MicroRNA hsa-miR-186*:mirSVR_highEffct hsa-miR-186*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.41E-49 1.91E-45 1.41E-48 1.30E-47 140 880 "XKR4,PTCHD1,OSBPL6,C1QTNF3,ALCAM,MYH7B,PHF12,PKP4,EPB41L5,NCOA1,SLC2A11,N4BP2L1,ADAM23,CACNA1A,CACNA1B,CALB2,CAST,METTL6,LARGE1,MAGI1,SOCS6,EPS15L1,RAB28,FAM189A2,CNTN1,AKAP6,CSNK1E,CTH,GIT2,DDX46,RAB39B,DMD,MED12,NR1D2,AASDH,EDN3,FSD1L,PLXNC1,IRAK4,EIF1,TUBD1,NRN1,STRADA,SLC9B2,FGF13,BAIAP2,UBE2E3,EVL,JKAMP,TMEM107,SMC2,OGA,GABRG2,ERAP1,ZNF559,DISC1,NFU1,TCERG1,COPS8,RAB30,TNRC6A,MAP7D2,RAB40B,CCDC184,KAT7,RNFT2,CELF5,MSL1,MYLK2,ZIC5,ITGAM,SLC35G1,KCND1,STXBP5,NCOA7,MAP2,SRSF12,PPM1L,MN1,ZNF680,MSI1,MSR1,MYO9A,ZC3H12B,NEK1,NF1,NFYA,SMIM7,EPB41L4B,PPP2R2B,KANSL1,RANBP3L,PRKACB,EPDR1,CNTLN,BDNF-AS,SPDL1,GTDC1,ELP2,MRAP2,SPIN3,ATP8B4,SEMA6D,NLGN1,ATF7IP,CPEB4,LIMCH1,MBD5,GLT8D1,RBM26,PBLD,CLASP2,SSTR1,ADHFE1,SYNE2,CAMTA1,ADGRL3,AGTPBP1,SYNE1,DOCK9,NSD1,PUM2,RNF216P1,KAT6B,RUNDC3B,AMACR,STXBP4,SGK3,PLEKHH2,BCL2L13,VAV1,CLDND1,RICTOR,XRCC4,RNF103,MPPE1,DNAH10,DOCK8,RNF170,DPF3" MicroRNA hsa-miR-329:mirSVR_highEffct hsa-miR-329:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.84E-49 2.15E-45 1.59E-48 1.46E-47 124 695 "ADD2,LRFN2,AP2A2,HACE1,ADGRF5,PHF12,BCAS1,RGS20,EIF4G3,ATP1B3,BCL7A,BMPR1B,CALB1,PTBP2,SPAG9,ARHGEF25,KRIT1,ZMYM4,SOCS6,B4GALT6,PLAA,CLTB,ARHGEF6,COL9A3,IGDCC3,RBM39,CRMP1,RNF14,ABCG1,CSNK1G3,PDE4DIP,HDAC9,LONRF1,DAPK1,EDNRA,PHF20L1,SUGP2,EIF4G1,CALCRL,ENPP6,ZSCAN30,FER,FGF12,SLC37A3,NBEA,POMT1,ST6GALNAC3,DISC1,WASHC2A,USP19,MALT1,MAP7D2,DCLK2,BTN2A1,PSIP1,RNFT2,MAP4K5,TNFAIP8L3,IGFBPL1,SMAP1,IL6ST,MARK1,POC1B,RTL5,NF1,NPY,PCSK5,PDE4D,OLA1,ZNF655,MAPKAP1,PRKACB,SLC26A11,PTPRG,FAM184A,OXR1,ERI2,ZDHHC4,ZFHX4,CCDC102B,RPE,RPL15,SEMA6D,LRFN5,SCN8A,FBXO11,NUBPL,WDR47,CPEB4,ZNF667,CMTR2,SNRPN,KDM3A,SP4,ELOVL4,SYN2,TACC1,TCEA1,ZEB1,PCDHB10,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TIAM1,HEY1,ERCC6L2,R3HDM1,UBE2H,PLEKHH2,CLDND1,ZBTB14,CIAPIN1,NAV3,UBE3B,KAT6A,HNRNPA3,PHTF2,NHSL1,FAM198A" MicroRNA hsa-miR-132:PITA hsa-miR-132:PITA_TOP PITA 4.32E-49 2.42E-45 1.78E-48 1.64E-47 88 338 "ELFN2,PCDH19,OSBPL8,SEMA6A,SEMA4G,TMEFF1,FUBP1,PTBP2,DCLK1,LARGE1,CFL2,FOXN3,RAB28,HECTD1,ARMC8,DOCK4,GAPVD1,ELMSAN1,POM121,SEC16A,DUSP9,E2F5,EPB41,NCALD,ETV1,NRN1,PRKAG2,FOXO3,AFF2,OGA,RAPGEF6,GHR,GPD2,FAM19A2,HAS2,SMAP1,TJAP1,PACRG,MAPT,MARK1,MEF2C,MEIS2,HNRNPM,NFYA,NOVA1,NRCAM,KSR2,PIK3R1,EPB41L4B,PPP2R5E,MAPK3,FAM184A,RDX,GTDC1,RFX3,ZFHX4,SETD5,SALL1,SEMA6D,CSRNP3,FAM81A,EPN2,SEPHS1,CCDC88A,SMARCA4,SOX3,SOX11,MYCBP2,CDK19,SS18,SEPT8,CAMTA1,ADGRL3,TCF4,PUM2,SIRT1,SLC44A1,HEY1,TRPS1,TSN,HIRA,SGK3,WIPF1,ZBTB14,NDRG4,RGS7BP,FXR1,ST8SIA2" MicroRNA hsa-miR-212:PITA hsa-miR-212:PITA_TOP PITA 4.32E-49 2.42E-45 1.78E-48 1.64E-47 88 338 "ELFN2,PCDH19,OSBPL8,SEMA6A,SEMA4G,TMEFF1,FUBP1,PTBP2,DCLK1,LARGE1,CFL2,FOXN3,RAB28,HECTD1,ARMC8,DOCK4,GAPVD1,ELMSAN1,POM121,SEC16A,DUSP9,E2F5,EPB41,NCALD,ETV1,NRN1,PRKAG2,FOXO3,AFF2,OGA,RAPGEF6,GHR,GPD2,FAM19A2,HAS2,SMAP1,TJAP1,PACRG,MAPT,MARK1,MEF2C,MEIS2,HNRNPM,NFYA,NOVA1,NRCAM,KSR2,PIK3R1,EPB41L4B,PPP2R5E,MAPK3,FAM184A,RDX,GTDC1,RFX3,ZFHX4,SETD5,SALL1,SEMA6D,CSRNP3,FAM81A,EPN2,SEPHS1,CCDC88A,SMARCA4,SOX3,SOX11,MYCBP2,CDK19,SS18,SEPT8,CAMTA1,ADGRL3,TCF4,PUM2,SIRT1,SLC44A1,HEY1,TRPS1,TSN,HIRA,SGK3,WIPF1,ZBTB14,NDRG4,RGS7BP,FXR1,ST8SIA2" MicroRNA hsa-miR-7:mirSVR_highEffct hsa-miR-7:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.82E-49 3.25E-45 2.40E-48 2.21E-47 154 1058 "ADD2,KIAA1211,SEMA6A,CARNS1,CCDC146,PHF12,TNRC6C,LINC00173,NCOA1,ATP1B3,ATP2B2,DPY19L3,ADAM23,ST3GAL5,SYNJ2,SCAPER,SGCE,CA8,SLC25A14,CD86,MAGI1,FOXN3,MS4A7,CNOT8,NDST3,TPP1,IGLON5,CNN3,ARMC8,AHCTF1,CPS1,CLIP3,CYBB,BOC,AIF1L,SPATA2,SV2B,DPYSL2,DTNA,ABCC5,SEZ6L2,FAM13A,PHF20L1,EGFR,EGR3,ENO2,ERBB4,MRPL37,NRN1,ACSL4,RACK1,CEP78,FCGR3A,GORAB,FGF13,IP6K2,SLC37A3,POMT1,SMC2,ATP2C1,STAU2,GAD1,DISC1,GCNT2,SULT1C4,GFER,GGT7,GRIN2C,KAT7,DHX35,INPP5B,HECTD2,PIK3AP1,ADAM11,MYCN,NTRK2,OCRL,CHAMP1,P2RX7,PAX6,PDE4B,PDE4D,MAPKAP1,STRN3,PRKCB,MAPK4,CNTLN,PTK2,FAM66C,FAM184A,OXR1,ERI2,CARF,RPL15,MEG3,NCBP3,SEMA6D,SATB1,SH3BGR,KIF16B,HKDC1,AMBRA1,FHOD3,R3HDM2,WDR47,SLC12A4,ELMO2,BTBD7,TET1,RCOR3,ANKRD36,SNCA,LMBRD1,TMCC1,MYO16,ZC3H13,PBLD,CLASP2,NXT2,ZSCAN29,ZC3H4,SYT1,ASTN2,TACR1,ANKRD12,TCF12,SYNE1,PCDHB15,FAM200B,ZNF106,CDH22,ASXL3,TLR4,FAM124A,SYNPO2,METTL3,SMUG1,RUNDC3B,TRO,PPIL6,RUSC1,RPL7L1,UGT8,FLRT2,WIPF1,WNT7A,KCNT2,AGMO,EMSY,STOX2,GAL3ST3,RGS7BP,ST7,PHTF2" MicroRNA hsa-let-7b-5p:Functional MTI Functional MTI miRTarbase 6.07E-49 3.40E-45 2.50E-48 2.30E-47 166 1215 "ABCF1,ASIC1,FZD9,MTUS1,ZNF578,CEP126,ZNF687,AMPH,FAM131A,AQP6,IGDCC4,ASPA,ATP1A1,ATP2A2,ALDH7A1,ATP6V0A1,BACH1,BCL7A,BMP7,WASF1,CA12,ENTPD6,L3MBTL4,TBRG4,QKI,PCYT1B,AHCTF1,SLC35F1,ENTPD4,CRY2,NCOR1,CS,LRIG1,IPCEF1,PPP1R16B,APPL1,PUM1,GAPVD1,INTS1,SCRN1,IP6K1,DNAL1,YTHDC1,ZC3H11A,POM121,MTX3,SEC16A,DMD,DNAH9,RCAN1,E2F5,E2F6,EDN1,ANKRD46,EIF4G2,MTSS1L,GPHN,MRPL37,TUBA1B,SCML2,DLC1,POLR1B,SEC23B,TRMO,PDLIM5,FAM49B,ERGIC3,CELF1,DISC1,GATM,SRCAP,NFU1,PPARGC1A,TXNL4A,TOX3,POLL,PRRC2B,FUT10,ATE1,RABL2A,ATXN2L,HSF2,RBPJ,IL6R,IBA57,KIF2A,KPNA5,MAP4,MEF2C,MOV10,DBNL,MSI1,THYN1,NACA,NME4,SLC11A2,NUCB2,OPRL1,PRTG,XRN1,NLE1,ZNF426,SEPT4,PPP2R5E,WDR25,PIGG,QDPR,USP47,OXR1,RBBP6,MSANTD2,RDX,DPF2,FIGN,KLHL11,ZFHX4,SETD5,C12orf49,SAFB,ATXN2,FOXRED1,SUPT20H,KIF27,SCAF8,CPEB3,FNDC3A,DZIP1,CPEB4,SMARCA4,SMARCC2,RBM34,ERC1,PEG10,ARHGAP26,DBNDD2,MCF2L2,TROVE2,NXT2,SYNE2,SYT1,TAF9,DNMBP,KIAA0930,USP22,SYNE1,SLC19A3,NSD1,DICER1,ZNF106,TIAM1,CBX5,TLR4,NR2E1,LRRC8A,TST,TUBB2A,UGT8,TBC1D15,ZNF28,DPYSL5,SMARCAD1,DHX33,SLC38A1,GDPD5,MRPL47,NHSL1" MicroRNA hsa-miR-138-1*:mirSVR_highEffct hsa-miR-138-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.45E-49 3.61E-45 2.66E-48 2.45E-47 131 778 "BRAP,KLHL13,ALCAM,FAM135A,LRCH2,BCAS1,TNRC6C,PRX,PPP4R4,ARNTL,CDK13,SLC4A4,RNF182,ATP6V0A1,BACH1,MPDZ,BID,CASTOR3,CALM1,PTBP2,CCNH,MTMR7,SRSF11,PLAA,HECTD1,TOGARAM2,ZFP28,PREPL,HAPLN1,TRIM69,SNCAIP,SEC24C,OSBPL3,CSNK1G3,DZIP3,DDX46,DNAH9,DPP6,DTNB,FAM78B,GOLT1B,E2F5,FRY,PHF20L1,EMX2,NRN1,FAM198B,TMEM132C,MED12L,SUCO,ATP13A4,FOLH1,C2orf88,UFM1,MEGF10,NEU3,USP19,GHR,ZNF638,PRDM5,KAT7,PSIP1,FRMD5,SMAP1,MSL1,METTL21A,GPR62,KCNJ16,KIT,SFXN5,ZNF92,MXI1,NFE2L2,NOVA1,P2RY1,GPR137C,GLIPR1L2,ABCB1,XRN1,PURG,PMP22,MAGEL2,PRKACB,BDNF-AS,TMEM260,STK32A,PTX3,TRIM68,RIC8B,SETD5,GSTCD,RPL15,FBXW7,ATP8B4,SUPT20H,ARHGEF40,BTBD7,TET1,CPEB4,LIMCH1,MBD5,USP33,ERC1,ADHFE1,SYNE2,PLCB1,COBL,MTCL1,ALG1,KIAA1107,AGTPBP1,TBCEL,KLHL4,SIN3B,CLASP1,PUM2,CSMD1,DCBLD1,ANKRD20A2,SSBP2,CLHC1,CCDC14,TBC1D15,ZNF781,MICU3,KCNT2,LYPD6,FSTL5,FIP1L1,PDSS2,JMJD1C" MicroRNA hsa-miR-623:mirSVR_highEffct hsa-miR-623:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.74E-49 3.77E-45 2.77E-48 2.55E-47 126 721 "NDRG2,CCDC85A,RNF157,BEND6,ADGRF5,ARNTL,TTLL9,BBS2,NRP2,CFLAR,CALB1,CALB2,KALRN,CCK,MTMR7,DCLK1,TAOK2,ZNF521,ZFP28,FAM171B,CRHBP,HAPLN1,SNCAIP,SEC24C,PHACTR3,APPL1,GREB1,RIMS2,ZSCAN23,RUBCN,CYBB,KATNAL2,ARMCX4,DDX46,RHOBTB1,FARSB,EDNRA,KLHL5,CELSR3,TMEM35A,C8orf37,EIF1,EPHB1,CLVS1,TMEM132C,CHST15,STRADA,GORAB,MED12L,IP6K2,NOP56,GABRA3,DENND2A,ADGRA3,FUT10,STMN2,PLCD4,ADAMTS6,HMGCR,HNMT,NKD1,LRRCC1,IL6ST,CYP27C1,LMO2,MBD1,MBNL1,MEIS1,MEIS2,SRSF12,BLOC1S2,NOVA1,GPR137C,GPR85,FAM218A,PKM,EXOSC10,SH3KBP1,PPP2R2C,PRKACB,MAPK10,HYDIN,CNTLN,MTMR10,TMEM260,PTPRB,PTPRD,PID1,OXR1,FIGN,PRIMA1,SLC25A36,NEK11,ZNF671,ATP8B4,TCP11L1,ATXN2,ATXN7,NLGN1,SLA,SLC9A5,SLC12A2,EPC1,DOK5,UNC5B,ZC4H2,PRRC2C,ZFP90,TRIM2,TCF12,SIK3,FAM200B,DICER1,TLR4,NR2E1,CDK20,TRIO,PCDH20,KCNT2,ZNF154,ZSCAN26,ZFAND5,KCNAB1,EPM2A,CASC15,RNF170" MicroRNA hsa-miR-423-5p:mirSVR_highEffct hsa-miR-423-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.64E-49 4.28E-45 3.14E-48 2.89E-47 122 677 "SYS1,ADRA1B,DPY19L2P4,AP2A1,ZNF608,KIAA1324,SPOP,FAM135A,ARRB2,CDK13,ATP6V1G2,ADAM15,BTK,KALRN,USP2,CPNE6,PPT2,CLTB,LETMD1,CLIP3,AATK,PDE4DIP,ZNF337,DGKB,DBI,SPATA2,DCTN1,HEPH,LYPD1,DDX46,TMCC2,MAMLD1,FIS1,FCF1,YAF2,EGFR,USPL1,EIF1,EPHB1,RAB9B,SIRPB1,EZH1,PTK2B,FCGR1A,FGFR3,SUCO,AGAP3,PDLIM5,CGREF1,CHL1,B4GALNT1,ERAP1,LRRC37A6P,GLYR1,GLUL,POLL,STON1,GRIN2D,AP4S1,NXPH3,HSPA1L,MSL1,INPP5B,KCND2,KCNQ3,MAT2A,MN1,TAGLN3,NNAT,SLC11A2,NRCAM,NTRK3,PCSK1,GPR173,ZNF655,PLTP,EPB41L4B,PPARA,PKIA,BCAS3,CNTLN,TMEM260,PTPRB,PRRT2,YY1AP1,SPIN3,ST6GALNAC6,SCP2,FERMT1,HKDC1,AMBRA1,SLC4A3,SLC14A1,SLC22A4,CDK5RAP2,KDM4C,ERC1,ATP10B,RGL1,STXBP1,PLCB1,SMG6,TCF12,SYNE1,NAT16,OBSL1,USP32P1,RELL2,PRRT1,R3HDM1,METTL3,DCBLD1,SSBP2,RPRM,OSBP2,ZNF177,EML6,ZNF225,DNALI1,HPS4,CASC15,MSRB3" MicroRNA hsa-miR-4320:mirSVR_highEffct hsa-miR-4320:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.86E-49 4.95E-45 3.64E-48 3.35E-47 129 757 "KCNH8,NCKAP5,TMEM132B,BRAP,HFM1,FAM135A,AMPD3,MAP4K3,MAGEE2,LGR5,ARNTL,DPY19L3,CCNH,AKAP6,COL9A1,AHCTF1,SMARCAL1,CREM,ANKRD44,CS,SEC24C,FAM169A,GREB1,RUBCN,EARS2,KIAA0586,AIF1L,ELMO1,SNAP91,FAM107B,E2F6,EDIL3,FCF1,RASGRP1,OPTN,SUGP2,RASA4,ELN,C8orf37,CEP85L,F5,TAOK3,STRADA,FDFT1,BAIAP2,IP6K2,FOLH1,SMC2,UFM1,STAU2,TUBGCP4,SULT1C4,MALT1,TXNL4A,ZNF638,LUZP2,GNAO1,PRUNE2,GRIA2,CIT,RNF165,AP4S1,SOX21,EID2B,MSL1,KCNN2,STXBP5,SFXN5,MEIS1,MYT1,NF1,CNOT4,NPY,NPTX2,NUCB2,OCRL,P2RX7,PCDH9,CDK18,GNG2,PRKAB2,RASGEF1B,PRKACB,EPDR1,MAPK10,HYDIN,WBP1L,LAMA1,PIGG,TMEM260,PTPRE,RAP1GDS1,OXR1,DPF2,SLC25A36,RIC8B,EXD2,CARF,NEK11,ZC3H14,ZNF331,SCN7A,ZFP2,WDR37,TET1,ANKRD36,KDM4C,TTBK2,JMJD6,NUDT10,TAL1,TPCN2,PCDHB9,TIAM1,ERCC6L2,TNS1,TP53BP2,SYNPO2,PLPPR2,ZIC1,LYPD6,ANKS1B,EMSY,PDSS2,UBE3B,JMJD1C,TIGD6,KLHDC1,SPATA13" MicroRNA hsa-miR-3179:mirSVR_highEffct hsa-miR-3179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.03E-49 5.05E-45 3.71E-48 3.41E-47 139 875 "OSBPL1A,APC,VAT1L,ZBTB10,NCOA1,ATP1A3,EIF4G3,STX16,ATP6V1G2,DST,SYNJ1,WASF1,HAP1,CERS5,CDC25B,ZMYM4,CLGN,TAOK2,C7orf61,NRXN3,PPT2,ARHGEF6,CNTN1,AKAP6,LETMD1,RTTN,SH2B1,ANKRD44,CLIP3,PDE4DIP,RUBCN,GAPVD1,HDAC4,CENPL,LIN54,SPOCK2,B3GAT3,C2CD2L,KIF19,DNM1,DMPK,SLC25A18,PDCD6IP,SNX29,PHC2,SUGP2,EIF1,HSD17B14,EPB41,MFSD10,EPHB1,RABEPK,SRRM1,SPEG,ETV1,DNAJC27,F8,TAOK3,ZSCAN30,STRADA,PPP1R1B,SLC9B2,GTF2IRD2,FGF1,FGF11,FGF12,CAMKK2,GLYR1,PSIP1,ATXN2L,ARHGAP36,AGBL5,ZNF546,LRRC25,LRRCC1,KIAA1755,ITPKA,KIT,L1CAM,STMN1,ASPRV1,MBNL1,AFDN,MMP16,MX1,MYO9A,NEK1,NOVA1,DNHD1,NPR2,IGSF11,PCDH9,PDPK1,PLIN1,SEPT4,EPB41L4B,SH3KBP1,PPM1B,PRKACB,PKIA,SPDL1,TMEM145,PID1,RAD17,OXR1,ERI2,NUDT11,SETD5,CARF,CCDC25,SGSM1,ATAT1,ZNF568,FAM192A,CSRNP3,SHMT2,R3HDM2,DHX30,SLC8A1,CCDC88A,DDN,STX1A,PRRC2C,SYNE2,MLST8,TAL1,ADGRL3,SMG6,SYNE1,CCDC173,PMS2CL,TIAM1,TPM2,UBE3A,VGF,WIPF1,NDRG4,MDH1B,JPH3" MicroRNA "ACCAAAG,MIR-9:MSigDB" "ACCAAAG,MIR-9:MSigDB" MSigDB 1.28E-48 7.14E-45 5.24E-48 4.82E-47 102 471 "ASIC1,RNF150,ESYT2,HECW2,ALCAM,ANK2,PARG,ARHGDIA,NCOA1,CCAR2,SYNJ1,MYRF,CALB2,KALRN,PTBP2,USP6,ARHGEF2,EVI5L,FAM19A5,QKI,CNTFR,COL9A1,TBPL1,CLOCK,C2CD2,NCOR2,OSBPL3,SOCS5,RIMS4,RIMS2,ARHGAP24,DGKB,ARMCX2,KLHL3,RHOBTB1,SACS,FAM107B,CPEB2,CNNM1,FRY,PHF20L1,EGR3,EIF5,TENM1,CHST15,FGF12,CAMKK2,GAD1,MTHFD2,CBX1,ADAMTS13,ADAMTS6,ACOT7,AGFG1,MBNL1,ADAM11,KITLG,MMP16,DBNL,NEK1,NPTX1,CNTN3,GPR85,ZNF655,CCSER2,XRN1,PMP22,PPARA,CNNM2,SNRK,TMEM260,RET,PRRT2,RIC8B,HUNK,SEMA6D,SCN2B,TRA2B,KIF21A,AMBRA1,CPEB4,CMTR2,TMCC1,FNBP1,SPART,NFASC,ERBIN,ELOVL4,STX1A,ANKRD12,TRIM2,DOCK9,SIRT1,AP4E1,RASD2,CELF4,SLC30A3,PRDM10,ITM2C,FAM13C,PHTF2,FRMD6" MicroRNA hsa-miR-583:PITA hsa-miR-583:PITA_TOP PITA 1.51E-48 8.45E-45 6.19E-48 5.70E-47 92 378 "ASIC1,ADCY6,KLHL13,AMPH,APC,PPFIA3,USP37,CASK,MARCH3,ZBTB10,CCAR2,SLC4A4,ATP1B3,LDLRAD4,THSD7A,SEPT7,MAGI1,FOXN3,LHX2,CLCN3,CLTC,BAG4,SEC24C,RIMS4,SLITRK5,DOCK4,GAPVD1,ZFYVE16,DBN1,ELMSAN1,NR1D2,CPEB2,SNX29,PHC2,EPB41L2,ERBB4,IP6K2,AFF2,NBEA,FAM49B,FUT9,FYN,GALC,C15orf41,MMADHC,PRRC2B,GPD1,RNF165,FAM107A,BACH2,GABARAPL2,NEGR1,ZIC5,CAMK2N2,MAT2A,CHIC1,LRP1B,MEIS1,MN1,MXI1,NEXMIF,ZC3H12B,NF1,CNOT4,PIK3C2A,LRRN3,PPP2R5E,PPP3CA,OXR1,RYR3,LRFN5,KIF16B,CPEB3,SHMT2,NLGN1,PPP4R3A,SLC11A1,SLC12A2,CPEB4,NKAIN2,ERBIN,PLCB1,CUX2,RPGRIP1L,PUM2,TRPS1,SSBP2,UBE3A,ZFAND5,NAV3,WNK3,KAT6A" MicroRNA hsa-miR-1305:PITA hsa-miR-1305:PITA_TOP PITA 1.71E-48 9.56E-45 7.00E-48 6.45E-47 100 453 "OSBPL8,SPOP,FAM135A,LRCH2,LCORL,RGS20,ZBTB10,ATP2B2,SEC11C,SYNJ1,LDLRAD4,CAMK2A,RUNX1T1,FOXN3,SOCS6,CLOCK,RIMS4,CNTNAP2,APPL1,PLCXD3,RIMS2,PPP6R2,KIAA0408,SPATA2,JAKMIP2,KLHL3,RHOBTB1,SACS,CPEB2,PDCD6IP,DTNB,KMT5B,TENM1,RCAN2,DNAJC27,CLVS1,CAMKK2,KHDRBS3,MEGF10,C15orf41,ARFIP1,GHR,SPIN1,PSIP1,HMGCR,IGF1,IPO5,STXBP5,NCOA7,MAP2,MARK1,MXI1,RTL5,NPTX1,PCDH9,PFKFB3,CCSER2,XRN1,PLCL1,STRN3,KANSL1,PKIA,CNNM2,BCAS3,TMEM255A,KHDRBS2,FIGN,RIC8B,ZFHX4,CLIP1,SALL1,SEMA6D,TRA2B,PPM1E,CHD9,PPP4R3A,SOX11,CDK19,LARP4,MPRIP,TTBK2,ARHGEF9,SYPL1,TCF4,DMXL2,RPGRIP1L,SZT2,DOK6,TRPS1,SGK3,FLRT2,TBC1D15,XPO1,ZIC2,EMSY,CADM2,KAT6A,PHTF2,JMJD1C,CPNE4" MicroRNA hsa-miR-581:mirSVR_highEffct hsa-miR-581:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-48 1.13E-44 8.26E-48 7.61E-47 140 893 "ACADM,BEND6,INTS2,NME5,WDR35,CC2D2A,DPP10,EP400,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,SPTBN4,ARNTL,RGS20,EIF4G3,TTLL9,SYNJ2,MTMR2,NFS1,LRRFIP1,NRXN3,C4orf33,QKI,MAP4K4,CNGA3,ARHGEF6,CNR1,ARMC8,MYRIP,MROH8,SEC24C,CSNK1E,SIPA1L1,GREB1,USP6NL,CYBB,DCAF8,KCTD8,IP6K1,PABPC5,TMCC2,GRIN3A,GOLT1B,EBF1,EDNRA,HIPK3,OPTN,FAM13A,SUGP2,KMT5B,AASS,CALCRL,RCAN2,ENPP6,ABCA8,SCML2,FCGRT,SMC2,APOPT1,ZNF605,CELF1,AP4B1,ZMAT1,ZNF559,DISC1,LRRC37A6P,PCDH17,BRD8,ZNF276,FERMT2,PRDM5,ARHGAP36,HMGCL,USP51,DHX35,ITGAM,KCNJ16,KCNN2,LAMP2,HECTD2,MAN2A2,MAT2A,MEIS1,NFIX,TBC1D25,OCRL,PCDH9,NALCN,FAM218A,ING3,MAPK10,DIRAS2,PTPRD,PTPRG,PTPRO,QDPR,CEP97,PBRM1,ZFHX4,FBXW7,ATP8B4,LRRK2,ABCA11P,TNFRSF19,SUPT20H,ZFP30,FBXO11,FAM214B,SEPHS1,ATF7IP,SNRPN,SP4,UHRF1BP1L,DBNDD2,CDK19,SSTR2,SS18,SYNE2,ARHGEF9,SYT1,ATMIN,ZFP90,CCDC173,TIAM1,ERCC6L2,TRO,RUSC1,TUBB1,USP1,CCDC14,VLDLR,ZNF708,ZNF138,ZNF195,STOX2,ST7,RNF170,MSRB3,NHSL1,FXR1" MicroRNA hsa-miR-221*:mirSVR_highEffct hsa-miR-221*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-48 1.15E-44 8.43E-48 7.77E-47 121 672 "SYS1,GALNT16,KIAA1324,EP400,MYH7B,PARG,TTLL9,ADGRB3,SCAPER,CALB1,KALRN,PTBP2,NFS1,METTL6,RGN,CNGA3,CNR1,SMARCAL1,GDA,ABCG1,SNCAIP,CSNK1G3,SOCS5,ERC2,CCDC144A,RIPOR2,DAPK1,GIT2,DBN1,ECM2,DNAJB6,DNM1L,HIPK3,EGR3,C3orf18,EPHB1,SRRM1,CEP85L,ZSCAN30,PPP1R1B,FGF12,MEX3B,PSD2,TRIM16,ATP2C1,STAU2,ERAP1,ALDH1L1,FREM1,PCDH17,TNRC6A,HTATSF1,PCLO,RASSF8,UBE2QL1,ARHGAP36,HMGCR,AGBL5,TCEAL6,SMAP1,IRF8,ZNF678,JAK2,MBNL1,MEIS1,POC1B,ZNF680,NEFH,NF1,NFE2L2,OGG1,CYTL1,FAM218A,RASGEF1B,MAPK10,GRAMD1C,SPDL1,TMEM260,PTPRG,OXR1,GTDC1,ZDHHC4,RGS3,RGS4,KLHDC8A,ROBO1,NEK11,EMID1,DGLUCY,ATXN7,KIF21A,CNKSR2,BTBD7,SNRPN,SOX3,SPART,SS18,NUDT10,IQCE,FBXW11,SATB2,AKTIP,ANKRD24,SMUG1,RUNDC3B,TSC1,TTC3,PLEKHH2,BCL2L13,ZNF708,ZNF138,ANKS1B,PCBP1-AS1,ADAMTS9,CIAPIN1,TRIM16L,WNK3,RGS7BP,UBE3B,PHTF2,FBXO36" MicroRNA hsa-miR-3190-5p:mirSVR_highEffct hsa-miR-3190-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.37E-48 1.88E-44 1.38E-47 1.27E-46 144 946 "OSBPL1A,KIAA1324,TAOK1,AMT,SUGT1P4-STRA6LP-CCDC180,PARG,TNRC6C,TMEFF1,MARK4,TMEM108,ATP2B2,RAB29,WASF1,ARHGEF2,LRRFIP1,RCBTB2,NDST3,PPT2,MAP4K4,FHL5,ARMC8,GDA,CS,LRIG1,OSBPL3,CTH,ARHGAP24,ZFYVE16,SPOCK2,PITPNC1,HEPH,RHOBTB1,TOM1,FCF1,PHF20L1,EGFR,PLEKHA1,ING4,TMEM35A,EMX2,EPHB1,NRN1,FGF12,FGFR1,SEMA4D,NOP56,AKAP3,ZBED3,USP21,STAU2,FYB1,INPP5K,PPARGC1A,ZNF638,KDM2B,LOXL3,WDFY3-AS2,TDRKH,ZNF496,COQ10A,HNMT,IPO5,STMN1,PACRG,CLEC18A,MARK1,MSI1,MSR1,MYO7A,NOVA1,DNHD1,NTRK3,P2RX7,PCDH8,PCSK1,PDE1C,ZNF655,ZFYVE21,MAPKAP1,HYDIN,CNNM2,ZNF844,OXR1,TRIM68,ERI2,RGS12,ZFHX4,TMLHE,C12orf49,MRAP2,ATP8B4,LRRK2,RPS20,ATAT1,ZNF331,RMI1,S100B,ZFP2,ZNF821,SH3BP2,CCDC92,NLGN1,SEC31A,SLC12A2,ELMO2,BTBD7,GKAP1,MYH15,MBD5,LMBRD1,SNRPN,RBM34,NFASC,ADHFE1,DNAJC9,PLCB1,SLC37A2,ZEB1,SYNE1,TNS2,MTMR14,TK2,R3HDM1,TP53BP2,CDK20,WNT7A,KCNT2,TCEAL7,SH3GLB2,DHX33,ZNF225,HPS4,ITM2C,PCBP4,WNK3,PDSS2,EPM2A,SMIM8,FBXO36,CASC15,TIGD6,IFT88,NETO2,SENP7" MicroRNA hsa-miR-5011-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-48 1.91E-44 1.40E-47 1.29E-46 119 653 "ABCF1,ADD2,ZNF608,HACE1,TAOK1,PCDH10,MARCH3,BACH1,FUBP1,CA8,CA12,THSD7A,RUNX1T1,TBRG4,CFL2,B4GALT6,C4orf33,QKI,TBPL1,ANKRD44,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,DBT,PITPNC1,SPATA2,SV2B,CDON,CPEB2,YAF2,MBNL2,PLEKHA1,CERCAM,TUBD1,RCAN2,ACSL4,FER,POLR1B,TMEM164,TRMO,ZBED3,CELF1,MPP6,GABRG1,GCK,MMADHC,PPARGC1A,TCERG1,COPS8,KCNMB4,TPPP,BVES,INSYN1,BACH2,USP51,NEGR1,HSF2,IGF1,ZIC5,SCIN,IL6ST,KCNB1,KLHL23,KCNN3,L1CAM,SMAD9,MMP16,NEXMIF,NCAM2,NELL2,NTRK3,PIK3R1,XRN1,PURG,LRP12,PPP1R1A,PPP2R5E,SNRK,PTPRD,CEP97,SH3TC2,PRIMA1,RIC8B,CARF,FBXW7,AP1AR,CSRNP3,ZFP30,SLC6A8,SLC8A1,SLC12A2,FAM126B,ZHX3,ERC1,STAU1,PRRC2C,SYP,TRIM2,SIK3,ZMAT3,BEX4,CSMD1,DOK6,RGMB,NR2C2,OSBP2,KCNK12,SMARCAD1,SLC30A4,MAP3K12,ZXDA,EVI5,STOX2,ADAMTS9,FAM182B,KAT6A" MicroRNA hsa-miR-1265:mirSVR_highEffct hsa-miR-1265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-48 1.94E-44 1.41E-47 1.30E-46 140 897 "KDM5D,XKR4,DPY19L2P4,HECW2,KCTD16,WDR35,TXNDC16,SMIM17,SPOP,OGT,PKP4,APAF1,ATP6V1G2,CFLAR,SYNJ1,DDR1,PTBP2,CAMK2A,VXN,CAST,ZNF501,CD38,CLGN,PLAA,FHL5,ARHGEF6,MAGED1,NRG2,FAM171B,AKAP12,RIMS4,PDE4DIP,CYBB,RIPOR2,MAML1,CHRDL1,DMD,DOCK2,DPYSL2,GOLT1B,E2F6,EDNRB,FCF1,TMTC1,EMX2,VPS13B,EXTL2,GMPR2,CLVS1,SH3YL1,KAT8,POLK,SCARA3,PDLIM5,ST6GALNAC3,FAM120B,DISC1,SULT1C4,COPS8,GRIA2,MSL1,FAM95B1,ZIC5,IL6ST,KCNN3,HECTD2,CLEC18A,MBNL1,SHC3,MEF2C,MEIS1,SRSF12,MEST,MYCN,NF1,NFE2L2,NOVA1,DNHD1,OPA1,GLIPR1L2,PDE3A,PDE4D,PFKFB2,PMP22,PSAT1,PPP2R5E,HYDIN,VPS13C,DEF8,TMEM260,PTPRE,PTPRG,PID1,RADX,TRIM68,PBRM1,SETD5,CARF,BAALC,GLDN,ATAT1,FNIP1,SEC14L1,SUPT20H,SH3GL3,CHD9,FNDC3A,NLGN1,SLC4A3,EPN2,CDK5RAP2,LIMCH1,DBNDD2,NXT2,SYT1,EXOC7,TAL1,FAM208A,ADGRL3,SYNE1,FRYL,FAM124A,SYNPO2,METTL3,TRO,DCBLD1,SSBP2,TTC3,PLEKHH2,BCL2L13,CCDC14,CLDND1,XRCC4,ATP6V0E2,ZNF154,FSTL5,EML6,UPF3A,CASC15,ADAMTSL3" MicroRNA hsa-miR-342-3p:mirSVR_highEffct hsa-miR-342-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.56E-48 1.99E-44 1.45E-47 1.34E-46 124 709 "ADORA2A,AP2A2,KCTD16,OSBPL8,TAOK1,SMIM17,ALCAM,DPP10,MYH7B,LGR5,TMEFF1,NUMB,CCAR2,NRP2,CA12,CAST,PRC1,METTL6,FBXO7,ARMC8,FAM149A,SLC4A8,MYRIP,ZFP28,GDA,HDAC9,MATR3,SPATA2,KIAA0753,PLPPR4,SPOCK3,CHRDL1,EGFR,DENND4A,ZNF585B,CEP78,SEC23B,NOP56,TRMO,NBEA,TPK1,NSG1,SARAF,COPS8,KDM2B,ADGRA3,GPD2,LPAR4,BTN2A1,SOX21,ADAMTS6,ATXN2L,CPT1C,MYLK2,ITGAM,METTL21A,KIF2A,NCOA7,PIK3AP1,MAN2A2,MBNL1,TM6SF1,MEIS1,KCTD6,POC1B,PTOV1,MXI1,P2RY13,DNHD1,NTRK2,PCSK5,PPM1B,SNRK,TMEM260,PTPRN2,ZNF793,PRIMA1,SLC25A36,RORB,NEK11,RPL15,SPIN3,ZNF568,FAM192A,RMI1,SGK1,NUBPL,KDM4D,NAPB,DMRTC1,SNAP25,SNCA,RBM34,CLSTN2,SAMSN1,TTBK2,PRRC2C,ARHGEF9,ADAMTS17,DNAJC9,MMS19,FAM208A,ZEB1,TCF12,DOCK9,NSD1,FRYL,SIRT1,TIAM1,PRRT1,SYNPO2,TRIO,AMACR,ZKSCAN5,RICTOR,PCDH20,ZNF711,CELF4,LAMP5,SMARCAD1,UPF3A,ZNF225,PRDM10,TMEM178A" MicroRNA "TTGCACT,MIR-130A:MSigDB" "TTGCACT,MIR-130A:MSigDB" MSigDB 5.07E-48 2.84E-44 2.06E-47 1.90E-46 91 374 "HECW2,PITPNM2,OGT,LRCH2,PHF12,NCOA1,ATP2B2,NRP2,LDLRAD4,USP6,SOCS6,PLAA,TPP1,CLTC,QKI,AKAP7,CLOCK,GDA,CSF1,LRIG1,SOCS5,PPP6R2,SNPH,LONRF1,MAML1,SPATA2,WDR20,DPYSL2,ABCC5,GOLT1B,KMT5B,PAN3,EMX2,ERBB4,ACSL4,MED12L,FOXF2,NBEA,ARFIP1,RAB30,TNRC6A,RNF165,SOX21,BACH2,AGFG1,KIT,MAP4,MBNL1,MYT1,CNOT4,NPTX1,PFKFB3,PSD,PTPRG,RBBP8,ROBO1,ROBO2,RTN1,RXRA,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,BTBD7,CPEB4,SNAP25,USP33,CDK19,TSPYL2,SPART,ERBIN,DIP2A,PLCB1,ANKRD28,ANKRD12,CAMTA1,TRIM2,DICER1,ZFPM2,SLC44A1,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,MAP3K12,WNK3" MicroRNA "TTGCACT,MIR-130B:MSigDB" "TTGCACT,MIR-130B:MSigDB" MSigDB 5.07E-48 2.84E-44 2.06E-47 1.90E-46 91 374 "HECW2,PITPNM2,OGT,LRCH2,PHF12,NCOA1,ATP2B2,NRP2,LDLRAD4,USP6,SOCS6,PLAA,TPP1,CLTC,QKI,AKAP7,CLOCK,GDA,CSF1,LRIG1,SOCS5,PPP6R2,SNPH,LONRF1,MAML1,SPATA2,WDR20,DPYSL2,ABCC5,GOLT1B,KMT5B,PAN3,EMX2,ERBB4,ACSL4,MED12L,FOXF2,NBEA,ARFIP1,RAB30,TNRC6A,RNF165,SOX21,BACH2,AGFG1,KIT,MAP4,MBNL1,MYT1,CNOT4,NPTX1,PFKFB3,PSD,PTPRG,RBBP8,ROBO1,ROBO2,RTN1,RXRA,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,BTBD7,CPEB4,SNAP25,USP33,CDK19,TSPYL2,SPART,ERBIN,DIP2A,PLCB1,ANKRD28,ANKRD12,CAMTA1,TRIM2,DICER1,ZFPM2,SLC44A1,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,MAP3K12,WNK3" MicroRNA "TTGCACT,MIR-301:MSigDB" "TTGCACT,MIR-301:MSigDB" MSigDB 5.07E-48 2.84E-44 2.06E-47 1.90E-46 91 374 "HECW2,PITPNM2,OGT,LRCH2,PHF12,NCOA1,ATP2B2,NRP2,LDLRAD4,USP6,SOCS6,PLAA,TPP1,CLTC,QKI,AKAP7,CLOCK,GDA,CSF1,LRIG1,SOCS5,PPP6R2,SNPH,LONRF1,MAML1,SPATA2,WDR20,DPYSL2,ABCC5,GOLT1B,KMT5B,PAN3,EMX2,ERBB4,ACSL4,MED12L,FOXF2,NBEA,ARFIP1,RAB30,TNRC6A,RNF165,SOX21,BACH2,AGFG1,KIT,MAP4,MBNL1,MYT1,CNOT4,NPTX1,PFKFB3,PSD,PTPRG,RBBP8,ROBO1,ROBO2,RTN1,RXRA,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,BTBD7,CPEB4,SNAP25,USP33,CDK19,TSPYL2,SPART,ERBIN,DIP2A,PLCB1,ANKRD28,ANKRD12,CAMTA1,TRIM2,DICER1,ZFPM2,SLC44A1,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,MAP3K12,WNK3" MicroRNA hsa-miR-4278:mirSVR_lowEffct hsa-miR-4278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-48 2.84E-44 2.07E-47 1.90E-46 131 792 "ACHE,XKR4,RNF157,ADD2,ADRA1D,LRFN2,CC2D2A,UNC79,ZNF687,DPP10,UPRT,FAM131A,CASK,RASL11B,ATP2B2,ADAM15,GPR146,SYNJ2,BTK,WASF1,MYRF,EVI5L,LOC730101,TIGD7,UBE2L6,NDST3,NRXN3,SLC35F1,SNCAIP,CSF1,CYBB,HDAC9,ARHGAP32,KLHL3,TMEM130,DMD,RPS6KL1,SLC12A6,DPYSL2,ACOT8,PHC2,CELSR3,GOLGA7,TENM1,EMX2,CHST15,KAT8,SLC9B2,SEMA4D,MEGF11,AHDC1,ADAM28,PPARGC1A,MALT1,FERMT2,GPT2,STMN2,C1QL4,RABL2A,FAM107A,ARHGAP36,ELOVL5,HMGCL,AGBL5,LRRC75A,SCIN,KCNN2,HECTD2,SHC3,MEIS2,MPP2,BLOC1S2,NEFH,NPTX1,NRCAM,SMIM11A,NTRK3,PCDH8,PCSK5,MAPKAP1,PPP5C,MASP1,SAMD9,PTPRN,PTPRN2,ROGDI,PRRT2,UBR7,EPHA10,GALNT10,FUZ,SHMT2,SLC11A1,SLC14A1,ABTB1,SMARCD3,BDP1,ZSWIM8,ZC3H13,SPTAN1,SPART,ZC4H2,TTBK2,ARHGEF9,NUDT10,CLASP1,SZT2,PCDHB9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZMAT3,AKTIP,THRA,R3HDM1,SSBP2,CLEC2L,UBTF,ATP6V0E2,NDRG4,LYPD6,CELF4,MEIS3,EMSY,FAM13C,FAM219B,MSRB3" MicroRNA hsa-miR-511:PITA hsa-miR-511:PITA_TOP PITA 5.52E-48 3.09E-44 2.24E-47 2.06E-46 105 508 "ADCY6,HECW2,PCDH19,ADGRF5,SEMA6A,ALCAM,BEGAIN,CDK13,EIF4G3,ATP2B2,RUNX1T1,LDB2,USP6,CDH2,FOXN3,NRXN3,CLTC,QKI,MAP4K4,ZNF521,CSNK1G3,PHACTR3,DCAF8,MYEF2,RAB39B,RASGRP1,FAM13A,MBNL2,EGR3,PLEKHA1,CALCRL,PAN3,DCTN4,EMX2,GPHN,ERBB4,EYA1,MRVI1,FGF13,PSD2,AFF2,AKAP3,KHDRBS3,CELF1,TPPP3,MSTN,AHDC1,PPARGC1A,SPIN1,TNRC6A,GLUL,HAS2,BACH2,HLF,HMGCR,NEGR1,CYP27C1,KTN1,MAP2,MBNL1,MEIS2,MITF,AFF1,MXI1,MYO6,CNOT4,CCSER2,PPP2R5E,TMEM104,QRICH1,RAP1GDS1,KHDRBS2,REV3L,ZNF532,DCUN1D2,ROBO2,ZC3H14,STK32B,HUNK,WDR37,HECW1,ARHGAP26,CDK19,RBM26,CLASP2,POGZ,SS18,ERBIN,RGL1,PHLDB1,ANKRD28,CAMTA1,AGTPBP1,SATB2,DOCK9,FRYL,LRRC8A,UBE2H,FLRT2,REEP1,CADM2,STOX2,PARP11,ADAMTSL3,FAM181A" MicroRNA hsa-miR-1262:mirSVR_highEffct hsa-miR-1262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.07E-48 3.39E-44 2.46E-47 2.27E-46 132 805 "RALGAPA1,BEND6,AGT,KCTD16,RTL9,OSBPL1A,TXNDC16,ARHGAP20,PKP4,SEMA4G,ARRB1,ARRB2,ZSCAN18,BARD1,SEC11C,ZNF599,SYNJ2,ARHGEF7,LURAP1,CAST,CD38,C1orf52,LRRFIP1,TAOK2,NRXN3,QKI,CNGA3,CPS1,CLIP3,CSF1R,ARHGEF10,FAM107B,DYNC1I1,DNM1L,EBF1,EDNRA,EDNRB,KLHL5,FSD1L,MBNL2,TMEM132E,PLEKHA1,EPHB1,MRPL37,TLR7,EXTL2,F8,KAT8,POLR1B,FGF11,FGF13,FGFR1,MEX3B,SLC37A3,STAMBP,DISC1,LRRC37A6P,GCNT2,WASHC2A,MALT1,PCLO,FAM222A,UBE2QL1,AGBL5,TCEAL6,SYTL4,NCOA7,MAN2A2,MAT2A,MATN2,MN1,MSR1,RTL5,TCEAL5,NEK1,NPY,NOVA1,SLC11A2,OPA1,ETFRF1,PCSK1,PDE4D,ZNF655,JAKMIP1,PURG,PPP2R5E,CEP41,PKIA,MTMR10,PTPRB,ZNF615,RIC8B,GSTCD,YY1AP1,RPE,SPIN3,ZNF568,SH3GL3,FERMT1,KIF16B,CHD9,SEC31A,SLC8A1,ATF7IP,TET1,RCOR3,DOK5,HECW1,KDM4C,IQSEC2,PBLD,ZSCAN29,SEPT8,COBL,ADGRL3,KLHL4,PCDHB7,C18orf54,ITGB3BP,ARL10,LRRC8A,USP1,ZFP37,ZNF142,EMSY,CADM2,FAM47E,EPM2A,RGS7BP,FAM13C,NETO2,JPH3" MicroRNA hsa-miR-4294:mirSVR_highEffct hsa-miR-4294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.71E-48 3.75E-44 2.72E-47 2.51E-46 113 592 "NCKAP5,KCTD16,OSBPL8,CC2D2A,SPOP,OGT,SEMA7A,MYH7B,PHF12,SUGT1P4-STRA6LP-CCDC180,MARK4,BMP7,CAMK2G,KRIT1,METTL6,CD86,DIS3L,RCHY1,IGDCC3,C2CD2,RGS6,UBXN2A,DOCK4,KATNAL2,ARHGAP24,DAPK1,ARMCX4,ELMO1,DDX46,EBF1,SUGP2,RCAN2,SRRM1,IGSF6,ETV1,ADGRV1,GTF2IRD2,POMT1,STAU2,DISC1,KIAA1841,TCERG1,DBF4,TDRKH,GRM8,RABL2A,GUCY1B1,IRAK3,RASSF8,NME9,LAMA2,MAP2,MEIS2,TAGLN3,NTRK2,ZNF827,PCSK5,FAM98B,FAM216A,PMP22,SDK2,PKIA,TMEM260,ACSS3,SUSD4,ROGDI,RASGRF1,CARF,ROBO2,GLDN,SGSM1,ADAL,ATAT1,SATB1,TNFRSF19,SHC4,CHD9,FNDC3A,SLC14A1,ATF7IP,ANKRD36,SNAP25,PBLD,SEPT8,SYN2,FAM208A,KLHL4,SATB2,ZEB1,TPCN2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,AP4E1,TMPO,R3HDM1,TPM1,SYNPO2,RUNDC3B,CCDC14,P2RY12,GUSBP1,CELF4,SPIRE1,SIGLEC10,CASC15,NHSL1" MicroRNA hsa-miR-885-5p:mirSVR_highEffct hsa-miR-885-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.77E-48 4.35E-44 3.15E-47 2.90E-46 117 636 "NDRG3,KIAA1211,NME5,SEMA6A,ARHGAP20,FAM135A,MAP4K3,PARG,STK33,DOCK11,SYNJ1,SCAPER,JAZF1,PRMT9,PTBP2,SPAG9,LRRFIP1,CHN2,QKI,SLC4A8,RCHY1,VCAN,PHACTR3,CTH,CYBB,HDAC9,DCAF8,ARMCX4,ZNF804A,RHOBTB1,SNAP91,USP3,CPEB2,PDCD6IP,ARRDC4,FCF1,RASGRP1,FRY,FAM13A,PHF20L1,EIF4G2,EYA1,ARMCX1,DLC1,UBE2E3,MEX3B,FOLH1,ATP2C1,OGA,HRASLS5,GABRG2,ADAM28,GPR75,GRM8,PSIP1,ADAMTS6,RASSF8,SOWAHA,IL6ST,KIF2A,KTN1,SYTL4,MBNL1,AFDN,MYO9A,CNOT4,SLC11A2,NRCAM,LOC100128398,PCDH9,PDE4D,CYTL1,FAM218A,PCDH18,ING3,SNRK,NWD1,OXR1,RASGRF2,KHDRBS2,RET,RNASEL,ZFHX4,C12orf49,CARF,LRRK2,TRAPPC13,SCN7A,SH3BGR,KIF21A,CPEB3,FAM81A,PPP4R3A,SEPHS1,SLC12A2,NAPB,TET1,SNRPN,ZNF423,SSTR2,ERBIN,SYPL1,TBCEL,ATMIN,SIN3B,DMXL2,SATB2,TPCN2,SLC44A1,KAT6B,PLEKHH2,EMSY,ADAMTS9,NAV3,WNK2,HNRNPA3,CASC15" MicroRNA hsa-miR-320a:PITA hsa-miR-320a:PITA_TOP PITA 9.97E-48 5.58E-44 4.03E-47 3.71E-46 102 481 "NDRG3,FMNL2,UNC5A,PCDH19,SEMA6A,CDK13,ZBTB10,TMEM108,CA8,CACNB4,VXN,LDB2,CDH2,ZMYM4,FOXN3,BAG4,RIMS4,PPP1R16B,FAM131B,HDAC4,DBN1,ARMCX2,MYEF2,RHOBTB1,DLX1,NR1D2,GOLT1B,SEMA3D,CELSR3,KMT5B,EGR3,PLXNC1,PAN3,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,FAM49B,FUT9,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,PDE3A,OLA1,MAGEL2,MINDY2,PPP2R2C,CEP41,PTPRG,TMEM255A,SLC25A36,FBXW7,HUNK,SEMA6D,FBXO11,BTBD3,WDR47,TMCC1,SOX11,LMO3,POGZ,SS18,KANK1,CAMTA1,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,KAT6B,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZSCAN26,EMSY,PRTFDC1" MicroRNA hsa-miR-320d:PITA hsa-miR-320d:PITA_TOP PITA 9.97E-48 5.58E-44 4.03E-47 3.71E-46 102 481 "NDRG3,FMNL2,UNC5A,PCDH19,SEMA6A,CDK13,ZBTB10,TMEM108,CA8,CACNB4,VXN,LDB2,CDH2,ZMYM4,FOXN3,BAG4,RIMS4,PPP1R16B,FAM131B,HDAC4,DBN1,ARMCX2,MYEF2,RHOBTB1,DLX1,NR1D2,GOLT1B,SEMA3D,CELSR3,KMT5B,EGR3,PLXNC1,PAN3,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,FAM49B,FUT9,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,PDE3A,OLA1,MAGEL2,MINDY2,PPP2R2C,CEP41,PTPRG,TMEM255A,SLC25A36,FBXW7,HUNK,SEMA6D,FBXO11,BTBD3,WDR47,TMCC1,SOX11,LMO3,POGZ,SS18,KANK1,CAMTA1,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,KAT6B,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZSCAN26,EMSY,PRTFDC1" MicroRNA hsa-miR-320c:PITA hsa-miR-320c:PITA_TOP PITA 9.97E-48 5.58E-44 4.03E-47 3.71E-46 102 481 "NDRG3,FMNL2,UNC5A,PCDH19,SEMA6A,CDK13,ZBTB10,TMEM108,CA8,CACNB4,VXN,LDB2,CDH2,ZMYM4,FOXN3,BAG4,RIMS4,PPP1R16B,FAM131B,HDAC4,DBN1,ARMCX2,MYEF2,RHOBTB1,DLX1,NR1D2,GOLT1B,SEMA3D,CELSR3,KMT5B,EGR3,PLXNC1,PAN3,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,FAM49B,FUT9,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,PDE3A,OLA1,MAGEL2,MINDY2,PPP2R2C,CEP41,PTPRG,TMEM255A,SLC25A36,FBXW7,HUNK,SEMA6D,FBXO11,BTBD3,WDR47,TMCC1,SOX11,LMO3,POGZ,SS18,KANK1,CAMTA1,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,KAT6B,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZSCAN26,EMSY,PRTFDC1" MicroRNA hsa-miR-320b:PITA hsa-miR-320b:PITA_TOP PITA 9.97E-48 5.58E-44 4.03E-47 3.71E-46 102 481 "NDRG3,FMNL2,UNC5A,PCDH19,SEMA6A,CDK13,ZBTB10,TMEM108,CA8,CACNB4,VXN,LDB2,CDH2,ZMYM4,FOXN3,BAG4,RIMS4,PPP1R16B,FAM131B,HDAC4,DBN1,ARMCX2,MYEF2,RHOBTB1,DLX1,NR1D2,GOLT1B,SEMA3D,CELSR3,KMT5B,EGR3,PLXNC1,PAN3,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,FAM49B,FUT9,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,PDE3A,OLA1,MAGEL2,MINDY2,PPP2R2C,CEP41,PTPRG,TMEM255A,SLC25A36,FBXW7,HUNK,SEMA6D,FBXO11,BTBD3,WDR47,TMCC1,SOX11,LMO3,POGZ,SS18,KANK1,CAMTA1,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,KAT6B,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZSCAN26,EMSY,PRTFDC1" MicroRNA hsa-miR-589:mirSVR_highEffct hsa-miR-589:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-47 5.83E-44 4.21E-47 3.88E-46 115 616 "ACTN1,NDRG2,SLC24A4,KIAA1324,SPOP,GPRASP2,PHYHD1,BCAS1,CADPS,NUMB,TMEM108,SYNJ2,SLC25A14,RUNX1T1,PRC1,ZNF501,FBXO7,QKI,HECTD1,CNTFR,SEC31B,CRYM,RGS6,LRIG1,PDE4DIP,ERC2,PHF14,RIMS2,DOCK4,ZFYVE16,FBXL5,PLPPR4,FAM107B,DPYSL2,DTNA,DTNB,ANKRD46,CNNM1,PHF20L1,AASS,GOLGA7,SRRM1,MRVI1,ABCA8,FCGR1A,FDFT1,MED12L,NBEA,PDLIM5,ERGIC3,AP4B1,TVP23A,GALC,RAPGEF6,PCDH17,TNRC6A,GPT2,PRUNE2,LPAR4,KAT7,ELOVL5,LRRC75A,MSL1,NKD1,L1CAM,NCOA7,MAN2A2,ZFYVE27,LYPLAL1,MAT2A,LRP1B,AFDN,MYT1,P2RY13,SEMA5B,RETREG1,PURG,MAGEL2,PPM1B,PPP1R1A,HYDIN,TMEM260,PTPRN2,MRPS18A,RNASEL,DCUN1D2,ROBO1,EPHA10,SPIN3,ATP8B4,LRFN5,ABLIM3,PPP4R3A,TTC17,TSPYL2,CLASP2,ZC4H2,KANK1,SYN1,ANKRD28,ZEB1,TPCN2,USP32P1,SLC44A1,FAM124A,RIMBP2,TPM1,METTL3,STXBP4,MGAT5B,PLPPR2,TMEM237,MPPE1,WNK3,FZD3" MicroRNA hsa-miR-1197:mirSVR_highEffct hsa-miR-1197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-47 6.50E-44 4.69E-47 4.32E-46 127 751 "ADCY6,CC2D2A,AK2,PCDH10,FAM135A,BIN1,PKP4,MADD,ATP1B3,DPY19L3,CFLAR,RAB29,CA4,CACNA2D1,PRC1,ZNF501,CBFA2T2,CD38,CDC25B,DCLK1,TIGD7,NDST3,TPP1,QKI,LY86,SLC4A8,CREM,SOCS5,PPP6R2,CCDC144A,TBC1D5,TMEM170A,PABPC5,ARMCX4,ZC3H11A,DDX46,HS3ST2,DNAJB6,FARSB,ANKRD46,EIF5,TENM1,RGS17,VPS13B,DNAJC27,ADGRV1,TMEM132C,TUBA1B,TMEM164,PRKAG2,FHL1,UFM1,CELF1,NSG1,GABRG2,TUBA8,SULT1C4,GDF9,ADAM28,PPARGC1A,TNRC6A,ZNF638,GNAL,PCLO,FAM19A2,RABL2A,FRMD3,HNF4G,JAK2,LAMP2,PAXBP1,MAT2A,MEIS2,NTRK3,P2RX7,FAM216A,SLC25A23,PNMA3,SH3KBP1,HYDIN,TMEM260,PTPRO,SUSD4,TRIM68,GTDC1,SLC25A36,CARF,PNMA8A,ELP2,KIAA0895L,LRRK2,SAFB,KIF21A,NUBPL,SLA,CCDC88A,SNAP25,KDM4B,USP33,PDZD2,SP4,KDM4C,ZC3H13,CDK19,NKAIN2,RGL1,PLCB1,DNMBP,ZEB1,SZT2,ARL10,ASXL3,TMPO,KAT6B,CDK20,AMACR,TSC1,TUBB2A,UGT8,BCL2L13,MTCH1,FTSJ1,ADAMTS9,CIAPIN1,UBE3B,NETO1,SENP7" MicroRNA hsa-miR-562:mirSVR_highEffct hsa-miR-562:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-47 7.57E-44 5.46E-47 5.03E-46 130 787 "ACADM,NCKAP5,ZNF608,KCTD16,KIAA1324,SEMA7A,ZBTB10,ATP2A2,N4BP2L1,DPY19L3,ATP6V1G2,ARHGEF7,C5,IL33,CACNB4,PRC1,CFL2,SRSF11,CHN1,HECTD1,SLC4A8,RNF14,CTH,ARHGAP24,MATR3,DDX46,PLPPR4,DNM1L,EDNRB,KMT5B,ASB3,EIF4G2,CALCRL,GPHN,SRRM1,F8,CEP78,GORAB,SLC9B2,FER,FGFR1,POLK,MEX3B,SYNCRIP,HVCN1,UFM1,ATP6V1H,ST6GALNAC3,NSG1,ABLIM2,ZMAT1,TRAF3IP2,USP19,GHR,PPARGC1A,BRD8,KCNMB4,CIT,PSIP1,GUCY1B1,IDH3B,RBPJ,ITGAM,LAMP2,LIG4,MEF2C,MEIS1,ZNF92,P2RY13,LRP12,PSAT1,EPB41L4B,TATDN3,PPP2R5E,RELN,SNRK,PIGG,PTPN13,PTPRB,PTPRD,PTPRG,TTC13,RAD17,RASGRF2,FIGN,SETD5,RPE,BAALC,LRRK2,ABCA11P,DGLUCY,SCP2,SH3BGR,PPM1E,KANSL3,SLC12A2,SLC14A1,INTS9,IFT122,ANKRD36,TMCC1,MYO16,TRERF1,ZC3H13,ZBTB43,SPART,PBLD,CLASP2,SEPT3,NECAB1,TACR1,PJA1,TAF9,TBCEL,PCDHB10,PCDHB4,PMS2CL,SIRT1,TPM1,RPRM,UBE3A,UCHL1,ZBTB14,ZNF711,TRIM9,EMSY,PRDM8,WNK3,FAM13C,SMIM8" MicroRNA hsa-miR-4257:mirSVR_highEffct hsa-miR-4257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-47 7.82E-44 5.64E-47 5.19E-46 131 799 "CLK4,KIAA1211,AK2,UNC79,MYH7B,SYNJ2,LURAP1,KALRN,CDH2,SRSF11,CHN2,CNOT8,EPS15L1,PPT2,QKI,IQCK,AKAP5,AKAP12,RNF14,CLIP3,CSNK1E,SUSD5,SOCS5,PDE4DIP,PHACTR3,CST3,DZIP3,CTH,ZC3H11A,PLPPR4,DMD,DYNC1I1,DPH1,ANKRD46,FAM13A,PHF20L1,EGFR,KMT5B,TENM1,SRRM1,FDFT1,ZNF589,NELFCD,STAMBP,TPK1,CELF1,FYN,ZMAT1,GALNT15,ACSS1,GATM,PPARGC1A,TNRC6A,LUZP2,FUT10,ZNF496,AGBL5,IDH3A,IDH3B,IL6ST,IL12A,SLC35G1,METTL21A,KCNK3,CREG2,L1CAM,LAMP2,SMAD1,MARK1,SRSF12,COL28A1,LAYN,HNRNPM,NEK1,NOVA1,DNHD1,CYTL1,ZNF655,PRKACB,PKIA,HYDIN,MASP1,PIGG,CNTLN,PTPRG,SLC25A48,TRIM68,ZFHX4,GSTCD,MRAP2,RPE,EPHA10,ABCA11P,ATAT1,ATXN7,ZFP2,NUBPL,ABLIM3,PPP4R3A,DMRTC1,ANKRD36,RBM34,DOP1A,CLASP2,CLSTN2,SST,DIP2A,PRRC2C,PLCB1,SLC37A2,FBXW11,SMG6,SATB2,TRIM2,SZT2,HIF3A,HEY1,FAM124A,CSMD1,TRIO,FAM155A,GUSBP1,ZFP37,TRIM9,TCEAL7,ZNF142,TMEM178A,CIAPIN1,MRPL47,UBE3B,CASC15" MicroRNA hsa-miR-553:mirSVR_lowEffct hsa-miR-553:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.50E-47 8.39E-44 6.04E-47 5.56E-46 116 629 "RALGAPA1,NCKAP5,USP31,PWWP2A,TBC1D14,WDR35,SPOP,CEP126,ZNF687,PHF12,NUMB,ADGRB1,BCHE,ARHGEF7,CALB1,CLDN10,TIGD7,B4GALT6,LHX2,EPS15L1,TPP1,FAM19A5,CNN3,ARMC8,SNCAIP,HDAC4,PLPPR4,SPOCK3,DNAJB6,ABCC5,EDNRB,HIPK3,FAM13A,EGFR,MBNL2,COPS4,PLEKHA1,ZNF549,SPEG,CDKL3,ETV1,TAOK3,SPSB4,FLT1,TMEM107,NEURL4,DISC1,GCNT2,AHDC1,GGT7,RNPS1,FERMT2,DIDO1,CLASRP,PSIP1,TOX2,SHISA6,INSM1,KCND1,STXBP5,KTN1,MAN2A2,MBP,ADAM22,MYO9A,NF1,NTRK2,PLIN1,MAPKAP1,STRN3,PPP3CA,NDUFS7,WBP1L,SNRK,TUG1,RASGRF1,ZDHHC4,DCUN1D2,ROBO2,CCDC25,CCDC102B,LRRK2,HSD11B1L,KCNIP3,SCAF8,FERMT1,SYBU,PREX2,ZFP1,DMRTC1,SNRPN,TMCC1,BDP1,SPART,CLASP2,CEP68,DIP2A,KANK1,SYN2,ANKRD12,FAM208A,FBXW11,SIRT1,ITGB3BP,RGMB,PPIL6,PLEKHH2,MGAT5B,RBFOX3,ZNF781,ZBTB14,NDRG4,ANKS1B,EMSY,GAL3ST3,PHTF2" MicroRNA "TGCCTTA,MIR-124A:MSigDB" "TGCCTTA,MIR-124A:MSigDB" MSigDB 1.77E-47 9.91E-44 7.13E-47 6.57E-46 105 514 "ABR,TMCC3,PLEKHH1,ESYT2,ZNF608,OSBPL6,SEMA6A,ALCAM,OGT,APBB2,VAT1L,CPNE5,IGDCC4,ARHGDIA,CADPS,DPY19L3,RGS9,NRP2,ARHGEF7,JAZF1,WASF1,MYRF,PTBP2,CACNA2D2,B4GALT6,LHX2,QKI,TMEM184B,CNN3,CNTN1,MYRIP,SNCAIP,LRIG1,OSBPL3,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,LONRF1,IST1,GIT2,DMD,CDON,E2F6,EDNRB,CELSR3,DCTN4,ETV1,EYA1,PCYOX1,ANKFY1,FERMT2,GRIA2,RNF165,BACH2,ELOVL5,NEGR1,ITGA7,NCOA7,MARK1,MITF,MKLN1,NFIX,CLDN11,CNTN3,PCDH8,CDK18,PDE4A,GPR85,STRN3,FA2H,PPARA,PPP2R5E,MAPK4,PTPRE,RAD17,DUSP15,MORC4,RYR3,SEMA6D,CASC3,EPN2,ATF7IP,LIMCH1,FAM219A,SP2,GLT8D1,NFASC,NKAIN2,NXT2,KANK1,TACC1,ATMIN,DICER1,SIRT1,TRPS1,OSBP2,VSNL1,SMARCAD1,NAV3,MARCH8,PHTF2,ZDHHC20" MicroRNA hsa-miR-934:mirSVR_highEffct hsa-miR-934:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-47 1.36E-43 9.75E-47 8.97E-46 111 578 "KCNH8,NDRG3,RNF150,DPY19L2P4,RTL9,CC2D2A,CDC42BPA,VAT1L,BCAS1,STK33,ATP2A2,N4BP2L1,BBS2,NRP2,SYNJ2,CAST,RUNX1T1,METTL6,SLC16A4,MAGI1,PLAA,BAG4,TOGARAM2,SLC35F1,SEC31B,PREPL,GDA,CLIP3,SNCAIP,CSNK1E,VCAN,RUBCN,GIT2,YTHDC1,GRIN3A,USP3,APH1A,EIF5,DCTN4,LRRC17,EPHB1,GPHN,ACSL4,SYNCRIP,UFM1,ZNF605,AP4B1,KIAA1841,GHR,MSL3,ZNF638,DCLK2,FAM19A2,PSIP1,MIER3,SYNPO,SOWAHA,LRRCC1,KCND2,KHK,PAXBP1,NCOA7,MBP,MXI1,MYCN,NF1,NOVA1,PDE4D,ZNF655,PURG,DRAM2,MINDY2,LRRN3,KANSL1,PRPSAP2,CNTLN,ELOVL2,TMEM260,PPP2R3C,OXR1,KHDRBS2,MSANTD2,ERI2,ZDHHC4,SETD5,SH3BGR,BTBD3,TET1,RCOR3,ANKRD28,SLC37A2,MTCL1,TAL1,TRIM2,SYNE1,PUM2,THRA,ACTR6,SYNPO2,DCBLD1,SSBP2,TTC3,USP1,RICTOR,ZBTB14,TCEAL7,ADAMTS9,FIP1L1,WNK3,PLSCR4,JMJD1C" MicroRNA hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA_TOP PITA 2.53E-47 1.42E-43 1.02E-46 9.37E-46 87 345 "XKR4,LRFN2,PCDH19,SEMA6A,TRMT9B,MAP4K3,FAM131A,TMEFF1,NCOA1,LURAP1,SEPT7,DLGAP2,FOXN3,B4GALT6,AKAP6,CLOCK,SNCAIP,SOCS5,ERC2,RIMS2,SPOCK2,ARMCX2,ALKBH8,POM121,CPEB2,FRY,MBNL2,EIF4G1,EPHB1,ERBB4,EYA1,TAOK3,FGF13,PRKAG2,FHL1,UBE2E3,MEX3B,FAM49B,FUT9,GABRB3,SPIN1,PCLO,MIER3,HNF4G,JAK2,PACRG,MARK1,MAT2A,AQP11,LRP1B,KITLG,MSI1,HS6ST3,RTL5,NFE2L2,NTRK2,PDPK1,GNG2,DIRAS2,RELN,TMEM260,TMEM255A,RAP1GDS1,MSANTD2,FIGN,PPM1E,CPEB3,SNAP25,TMCC1,FAM126B,SOX11,SP4,ZNF423,SYP,WSCD1,TRIM2,PUM2,TRPS1,UBE3A,FLRT2,ZIC2,ZNF24,ZBTB38,ZFAND5,CADM2,ADAMTS9,NETO2" MicroRNA hsa-miR-514:mirSVR_highEffct hsa-miR-514:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.94E-47 1.64E-43 1.18E-46 1.09E-45 134 840 "KCNH8,PWWP2A,PPFIA3,CDC14B,PLA2G4C,MARK4,NCOA1,BACH1,ADGRB3,SEC11C,JAZF1,CBFA2T2,CLGN,CHN1,CHN2,TAOK2,RAB28,NRXN3,FAM149A,MYRIP,TRIM69,CSNK1G3,FAM169A,HDAC9,KIAA0586,DGKB,SV2B,NR1D2,GOLT1B,E2F6,EDIL3,EGFR,PCOLCE2,SUCO,SYNCRIP,FLT1,SLC37A3,NSG1,TVP23A,B4GALNT1,SULT1C4,GLI2,DCLK2,LPAR4,GRIA2,GRIK4,GRM8,RASSF8,HMGCR,ZNF491,CELF5,IDH3B,SLC35G1,KCNB1,LIG4,HECTD2,NCOA7,MATN3,MEIS2,POC1B,AFDN,ADAM22,MXI1,IDNK,NNAT,NRCAM,PCSK5,PLCL1,STRN3,TATDN3,SLC26A11,GRAMD1C,HYDIN,TMEM260,EML5,PTPRG,SUSD4,NWD1,ENOX1,KHDRBS2,RFX3,SLC25A36,TMLHE,CCDC102B,BAALC,ZC3H14,RTN1,SCN8A,PEAR1,FNDC3A,SEC31A,SEPHS1,NAPB,ZNF667,TTC17,BDP1,SPP1,ERC1,ITPRID2,SULF2,ARHGEF9,VPS13A,C12orf76,TBCEL,SIN3B,TCF12,USP22,SZT2,PCDHB6,TEK,DICER1,ITGB3BP,CDH22,NACC2,TPM1,ZNF346,METTL3,STXBP4,TTTY15,EIF4ENIF1,UGT8,RBFOX3,LYPD6,ZNF142,FSTL5,EML6,ZNF189,SLC30A4,MDH1B,NAV3,KCNAB1,HNRNPA3,RNF170,NETO2" MicroRNA hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA_TOP PITA 3.25E-47 1.82E-43 1.30E-46 1.20E-45 81 295 "ABR,TMCC3,USP31,ALCAM,PKP4,TMEFF1,NCOA1,DPY19L3,SYNJ1,JAZF1,WASF1,CALB1,EVI5L,NUMBL,MAP4K4,AKAP6,MYRIP,CLOCK,CSNK1G3,CNTNAP2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,AGAP2,GABRA3,CPLX2,MSTN,LOXL3,PCLO,TPPP,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RET,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,TRIM67,FAM126B,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,ATMIN,SATB2,TCF12,DOCK9,THRA,RELL2,POLR3H,SLC30A3,NAV3" MicroRNA hsa-miR-449a:PITA hsa-miR-449a:PITA_TOP PITA 3.25E-47 1.82E-43 1.30E-46 1.20E-45 81 295 "ABR,TMCC3,USP31,ALCAM,PKP4,TMEFF1,NCOA1,DPY19L3,SYNJ1,JAZF1,WASF1,CALB1,EVI5L,NUMBL,MAP4K4,AKAP6,MYRIP,CLOCK,CSNK1G3,CNTNAP2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,AGAP2,GABRA3,CPLX2,MSTN,LOXL3,PCLO,TPPP,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RET,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,TRIM67,FAM126B,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,ATMIN,SATB2,TCF12,DOCK9,THRA,RELL2,POLR3H,SLC30A3,NAV3" MicroRNA hsa-miR-34a:PITA hsa-miR-34a:PITA_TOP PITA 3.25E-47 1.82E-43 1.30E-46 1.20E-45 81 295 "ABR,TMCC3,USP31,ALCAM,PKP4,TMEFF1,NCOA1,DPY19L3,SYNJ1,JAZF1,WASF1,CALB1,EVI5L,NUMBL,MAP4K4,AKAP6,MYRIP,CLOCK,CSNK1G3,CNTNAP2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,AGAP2,GABRA3,CPLX2,MSTN,LOXL3,PCLO,TPPP,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RET,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,TRIM67,FAM126B,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,ATMIN,SATB2,TCF12,DOCK9,THRA,RELL2,POLR3H,SLC30A3,NAV3" MicroRNA hsa-miR-449b:PITA hsa-miR-449b:PITA_TOP PITA 3.25E-47 1.82E-43 1.30E-46 1.20E-45 81 295 "ABR,TMCC3,USP31,ALCAM,PKP4,TMEFF1,NCOA1,DPY19L3,SYNJ1,JAZF1,WASF1,CALB1,EVI5L,NUMBL,MAP4K4,AKAP6,MYRIP,CLOCK,CSNK1G3,CNTNAP2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,AGAP2,GABRA3,CPLX2,MSTN,LOXL3,PCLO,TPPP,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RET,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,TRIM67,FAM126B,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,ATMIN,SATB2,TCF12,DOCK9,THRA,RELL2,POLR3H,SLC30A3,NAV3" MicroRNA hsa-miR-632:mirSVR_highEffct hsa-miR-632:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.32E-47 1.86E-43 1.33E-46 1.23E-45 123 712 "XKR4,PTCHD1,BEND6,INTS2,ANK2,PHF12,ATP2A2,DPY19L3,ADGRB3,RGS9,SGCE,SPAG9,NFS1,ZBED1,MAGI1,TIGD7,PPT2,SLC4A8,HAPLN1,ABCG1,SNCAIP,SEC24C,CSNK1G3,SIPA1L1,VCAN,FAM169A,SLITRK5,RIMS2,MATR3,DDX46,EXOG,E2F5,CERCAM,DCTN4,DENND4A,RASL12,REEP2,FAM198B,TUBB3,CEP78,GORAB,FER,SUCO,FOXF2,FLT1,ANKFY1,NELFCD,ZNF605,NSG1,C15orf41,GFRA2,PPARGC1A,RAB30,MSL3,ZNF638,GNAO1,FUT10,PSIP1,NEGR1,SMAP1,IDH3B,IGF1,SCIN,KCND2,MBNL1,LRP1B,MEF2C,MMP16,MYO7A,NRCAM,NTRK2,NUCB2,GNG2,PKD1,SNX10,JAKMIP1,PMP22,ING3,SEPT4,POLR2F,MAPK10,GRAMD1C,MASP1,SNRK,CNTLN,PTPN13,PTPRE,TTC13,FAM66C,RASGRF2,RDX,CARF,KIAA0895L,ABCA11P,ATXN2,CASC3,FNDC3A,FAM81A,SLC6A8,BTBD7,CPEB4,RCOR3,PDZD2,TSNAXIP1,SP4,ZC3H13,LHPP,SEPT8,SYP,C12orf76,DNMBP,FBXW11,GPRIN3,FAM200B,AKTIP,UBE2H,OSBP2,TRIM9,ZNF45,LYPD6,EML6,ZSCAN26,TIGD6" MicroRNA hsa-miR-133b:TargetScan hsa-miR-133b TargetScan 3.33E-47 1.87E-43 1.33E-46 1.23E-45 102 487 "GALNT16,ADCY5,ADCY6,ESYT2,KCTD16,AK2,ABCD2,PITPNM2,ANK2,PPFIA3,ARHGDIA,ARRB1,CDK13,PDE8B,ATP2A2,JAZF1,MYRF,CACNA1B,CALM1,PTBP2,RUNX1T1,CCNT1,FOXN3,FAM19A5,QKI,LETMD1,HAPLN1,ANKRD44,CSNK1G3,PITPNM3,CCDC144A,ARHGAP24,MAML1,AIF1L,ELMO1,MTX3,ANKRD46,FAM13A,EGFR,PAN3,ENPP6,CEP85L,EYA1,MED12L,FGF1,FGFR1,CELF1,DOT1L,IQGAP2,CPLX2,PCDH17,RAB30,GRIA2,PTPRT,DDX19B,MIER3,HLF,CELF5,NKD1,RBPJ,IL6ST,MEIS1,MEIS2,DBNL,SAMD5,NCAM2,NELL2,NFYA,PCSK5,PDE1C,GPR173,PFKFB3,PIK3C2A,KCTD15,PPP2R5E,PRKCB,CNNM2,PTPRD,PRRT2,RFX3,KLHL11,EXD2,AP1AR,SCN2B,CASC3,HSPA4L,KIF21A,ARX,CNKSR2,BTBD3,HECW1,ANKRD28,ANKRD12,FAM208A,FBXW11,CUX2,ARHGAP9,AP4E1,ELP5,DCBLD1,ELFN1,PHTF2" MicroRNA hsa-miR-133a-3p.2:TargetScan hsa-miR-133a-3p.2 TargetScan 3.33E-47 1.87E-43 1.33E-46 1.23E-45 102 487 "GALNT16,ADCY5,ADCY6,ESYT2,KCTD16,AK2,ABCD2,PITPNM2,ANK2,PPFIA3,ARHGDIA,ARRB1,CDK13,PDE8B,ATP2A2,JAZF1,MYRF,CACNA1B,CALM1,PTBP2,RUNX1T1,CCNT1,FOXN3,FAM19A5,QKI,LETMD1,HAPLN1,ANKRD44,CSNK1G3,PITPNM3,CCDC144A,ARHGAP24,MAML1,AIF1L,ELMO1,MTX3,ANKRD46,FAM13A,EGFR,PAN3,ENPP6,CEP85L,EYA1,MED12L,FGF1,FGFR1,CELF1,DOT1L,IQGAP2,CPLX2,PCDH17,RAB30,GRIA2,PTPRT,DDX19B,MIER3,HLF,CELF5,NKD1,RBPJ,IL6ST,MEIS1,MEIS2,DBNL,SAMD5,NCAM2,NELL2,NFYA,PCSK5,PDE1C,GPR173,PFKFB3,PIK3C2A,KCTD15,PPP2R5E,PRKCB,CNNM2,PTPRD,PRRT2,RFX3,KLHL11,EXD2,AP1AR,SCN2B,CASC3,HSPA4L,KIF21A,ARX,CNKSR2,BTBD3,HECW1,ANKRD28,ANKRD12,FAM208A,FBXW11,CUX2,ARHGAP9,AP4E1,ELP5,DCBLD1,ELFN1,PHTF2" MicroRNA hsa-miR-602:mirSVR_lowEffct hsa-miR-602:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-47 1.92E-43 1.37E-46 1.26E-45 107 538 "ADCY6,PLEKHH1,PWWP2A,CASKIN1,C1QTNF1,PDZD4,PHF12,PKP4,PPP4R4,EIF4G3,DPY19L3,TTLL9,DNAJC27-AS1,KSR1,ARHGEF7,CACNA1B,CALM1,P2RX6,TIGD7,TAOK2,RAB33A,FAM189A2,CSNK1E,PITPNM3,PUM1,DOCK4,MATR3,CASP8AP2,DNM1L,WDPCP,HIPK3,RCAN2,EPHB1,ADGRV1,ABCA8,TAOK3,SEC24B,FHL1,IP6K2,CHL1,ERAP1,C15orf41,DISC1,CPLX1,ALDH1L1,TOX3,STARD3,DCLK2,CCDC184,GPR37,HNMT,HSPA1L,C2CD4C,NCOA7,MARK1,ADAM11,MYT1,FXYD7,NPTX1,PCDH8,CDK18,PDE4B,ZDHHC8,NALCN,CCSER2,NLE1,FAM216A,SDK2,SH3KBP1,PRKACB,WDR25,PTPRN2,RAD51D,DPF2,MRPS18A,ZFHX4,SETD5,ATAT1,MYO18A,SLC6A11,SLC11A1,LGI3,ANKRD36,MYO16,USP33,FAM219A,LHPP,ZSCAN29,KANK1,TACR1,TAL1,IQCE,DMXL2,CUX2,TCF12,DOCK9,FAM189A1,TMEM9,TP53BP2,EIF4ENIF1,PDIA2,BCL2L13,VLDLR,ZFP41,TMEM198,SPIRE1,DOCK8" MicroRNA hsa-miR-635:mirSVR_highEffct hsa-miR-635:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-47 2.66E-43 1.90E-46 1.75E-45 118 658 "ABCF1,KDM5D,NDRG3,KLHL32,GALNT13,ADD2,PTCHD1,AP2A2,HECW2,CC2D2A,HFM1,TAOK1,LCORL,PKP4,PCDHGB4,TTLL9,BACH1,ARHGEF25,LDB2,P2RX6,MS4A7,QKI,CNR1,AKAP7,SUMF2,ABI3BP,RIPOR2,LONRF1,DAPK1,YTHDC1,DLX1,DMD,DNM1,DYNC1I1,DPP6,TOM1,AASDH,EDNRB,APH1A,EPB41L2,SRRM1,RRAGB,GMPR2,F5,SLC37A3,SMC2,APOPT1,CAMKK2,ATP2C1,ST6GALNAC3,BRSK1,ZMAT1,MEGF11,GAD1,INPP5K,LRRC37A6P,GATM,CBX1,DCLK2,SOX21,ARHGAP36,HMGCL,KCNJ16,HECTD2,MSI1,NF1,SLC11A2,PCDHGC3,PCDH9,CDK18,DUSP26,DRAM2,PPP3CA,SNRK,STK32A,PTPRE,RAD51D,ZDHHC14,RNASEL,ZFHX4,EXD2,HSD11B1L,RTN1,ATXN7,ARHGEF40,CABCOCO1,BDP1,IQSEC2,NKAIN2,SSPO,JMJD6,TACC1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,PCDHB10,RUNDC3B,MTCH1,VLDLR,PCDH20,ZBTB14,AGMO,LYPD6,ZNF138,ZSCAN26,MAP3K12,SEMA3B,MPPE1,CASC15,JMJD1C" MicroRNA hsa-miR-28-3p:mirSVR_highEffct hsa-miR-28-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.86E-47 2.72E-43 1.94E-46 1.78E-45 126 749 "PWWP2A,AP2A2,ZNF608,ABCD2,LRCH2,ANK2,PHF12,SHROOM2,PPP4R4,CDK13,ATP1B3,STX16,RNF182,SCAPER,CACNA1G,C5,RGN,C1orf52,C4orf33,SRP14-AS1,HECTD1,AHCTF1,FAM171B,CSF2RA,VCAN,PUM1,EARS2,LIN54,RHOBTB1,SACS,DMD,DTNA,DTNB,ANKRD46,PHF20L1,PLEKHA1,C8orf37,RASL12,EZH1,ACSL4,CEP78,ZSCAN30,GORAB,FOXO3,EFCAB2,STAU2,FYN,RAPGEF6,ERAP1,SULT1C4,LUZP2,GRIA2,DIDO1,FRMD3,ELOVL5,HMGCR,HNF4G,KCNJ16,KIT,LAMP2,SFXN5,SYTL4,MARK1,MBNL1,MEIS1,MXI1,NFE2L2,GPR85,PIK3C2A,KCTD15,VPS13C,PTPRG,USP47,ACSS3,CCDC40,RAD51D,NWD1,GTDC1,FIGN,NUDT11,ZFHX4,SUGCT,SETD5,GSTCD,TCP11L1,RMI1,SEMA6D,ATXN7,SCN8A,FNIP1,ST6GAL1,NLGN1,ABLIM3,SLC9A5,DMRTC1,SNAP25,TRERF1,FNBP1,UHRF1BP1L,CDK19,CLASP2,ZC4H2,SS18,STAU1,NEK4,DIP2A,STXBP1,ARHGEF9,PLCB1,MTCL1,TBCEL,TRIM2,RPGRIP1L,SLC35G2,FAM200B,AKTIP,SLC44A1,BHLHB9,BEX4,RGMB,STXBP4,ANKS1B,EMSY,KCNAB1,KLHDC1,GAN" MicroRNA hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA_TOP PITA 5.52E-47 3.09E-43 2.20E-46 2.03E-45 91 384 "ABHD6,MTUS1,OSBPL8,ALCAM,FAM135A,C6orf89,MTMR2,JAZF1,GPC2,PTBP2,CERS5,C1orf52,LRBA,MAGI1,NRXN3,MAP4K4,CNR1,APPL1,PUM1,DOCK4,DAPK1,BRINP1,ELMSAN1,FBXL5,KLHL3,CDON,CASP8AP2,RCAN1,DNAJB6,GOLT1B,HIPK3,FRY,YAF2,KMT5B,EGR3,EIF4G2,EIF1,ERBB4,SUCO,MEX3B,FUT9,ARFIP1,PPARGC1A,MSL3,MAP4K5,MIER3,ZIC5,KCNQ3,MAT2A,CHIC1,MITF,MKLN1,MXI1,NFIX,PCDH8,PRTG,PDE4B,PDE4D,PIK3C2A,PLCL1,LRP12,RAP1GDS1,ENOX1,RBBP6,PBRM1,ZFHX4,SEMA6D,FNIP1,SGK1,CPEB3,CHD9,CPEB4,COA1,LMO3,ERBIN,CAMTA1,ADGRL3,FBXW11,TCF4,ZFPM2,AP4E1,SLC44A1,TRPS1,VSNL1,ZIC2,MICU3,EMSY,FAM13C,ACTR3B,SENP7,JPH3" MicroRNA hsa-miR-517b:mirSVR_lowEffct hsa-miR-517b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.67E-47 3.17E-43 2.26E-46 2.08E-45 115 626 "KCNH8,ADD1,NME5,OSBPL6,ADGRF5,SPARCL1,ALCAM,TRMT9B,ZFAT,DPP10,CCDC146,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBB2,PHYHD1,ZNF582,MPDZ,CABP7,ISPD,ARHGEF2,NOG,HECTD1,IGLON5,ZNF521,VCAN,VAC14-AS1,SLITRK5,USP6NL,CCDC144A,ARHGAP24,DAPK1,DBN1,MFAP3L,GRIN3A,USP3,CPEB2,DNAJB6,EDN1,RASGRP1,PLEKHA1,STARD3NL,C8orf37,PAN3,TAOK3,FECH,POLR1B,FOXF2,SLC37A3,ERGIC3,FYB1,TOX3,HTATSF1,LPAR4,PCLO,GRIA2,GRM8,BTN2A1,HAS2,TNFAIP8L3,C9orf129,NKD1,ITGAM,KCNN2,LIG4,MARK3,MEIS2,TAGLN3,ZC3H12B,NDP,NELL2,PDE3A,PDE4D,ENPP2,SEMA5B,FAM216A,STRN3,ING3,KANSL1,CEP41,PKIA,EPDR1,ZIK1,PTPN13,FAM184A,RFX3,RGS12,RIC8B,LGI2,CARF,ROBO1,ROBO2,LRRK2,TRA2B,CPEB3,WDR47,SEPHS1,RCOR3,ANKRD36,SNCA,MBD5,FNBP1,ZBTB43,TROVE2,AGTPBP1,MGRN1,RPGRIP1L,ZFPM2,AP4E1,TPM1,FAM155A,USP1,CELF4,EML6,WNK2,FAM198A" MicroRNA hsa-miR-204:PITA hsa-miR-204:PITA_TOP PITA 5.79E-47 3.24E-43 2.30E-46 2.12E-45 96 431 "KCNH8,ADCY6,KLHL13,ZNF578,SEMA6A,OGT,CDH2,CCPG1,FOXN3,SOCS6,CHN2,PCYT1B,ZNF521,RBM39,GAPVD1,DCAF8,HDAC4,LONRF1,TM9SF4,RHOBTB1,SNAP91,FAM107B,SLC12A6,PDCD6IP,FRY,APH1A,EPHB1,RPS6KC1,ACSL4,SCML2,SUCO,AGAP2,SLC37A3,NBEA,KHDRBS3,MEGF10,GABRB3,GABRG2,ARFIP1,GGT7,PPARGC1A,TOX3,TPPP,MAP4K5,FRMD5,MIER3,ELOVL5,INSM1,JAK2,NCOA7,MBNL1,MEF2C,MGAT3,KITLG,SAMD5,MXI1,NOVA1,NPTX1,PCDH9,PRTG,RETREG1,XRN1,SNRK,PTCH1,PTPRD,PTX3,PID1,TMEM255A,USP47,ZFHX4,FBXW7,CLIP1,FNIP1,PPM1E,KIF16B,TRIM67,CPEB4,RCOR3,SOX11,PEG10,ZNF423,LMO3,ERBIN,RGL1,ANKRD12,CAMTA1,TCF4,SATB2,TCF12,SIRT1,FLRT2,TMEM237,PRDM10,WNK3,RGS7BP,ST7" MicroRNA hsa-miR-211:PITA hsa-miR-211:PITA_TOP PITA 5.79E-47 3.24E-43 2.30E-46 2.12E-45 96 431 "KCNH8,ADCY6,KLHL13,ZNF578,SEMA6A,OGT,CDH2,CCPG1,FOXN3,SOCS6,CHN2,PCYT1B,ZNF521,RBM39,GAPVD1,DCAF8,HDAC4,LONRF1,TM9SF4,RHOBTB1,SNAP91,FAM107B,SLC12A6,PDCD6IP,FRY,APH1A,EPHB1,RPS6KC1,ACSL4,SCML2,SUCO,AGAP2,SLC37A3,NBEA,KHDRBS3,MEGF10,GABRB3,GABRG2,ARFIP1,GGT7,PPARGC1A,TOX3,TPPP,MAP4K5,FRMD5,MIER3,ELOVL5,INSM1,JAK2,NCOA7,MBNL1,MEF2C,MGAT3,KITLG,SAMD5,MXI1,NOVA1,NPTX1,PCDH9,PRTG,RETREG1,XRN1,SNRK,PTCH1,PTPRD,PTX3,PID1,TMEM255A,USP47,ZFHX4,FBXW7,CLIP1,FNIP1,PPM1E,KIF16B,TRIM67,CPEB4,RCOR3,SOX11,PEG10,ZNF423,LMO3,ERBIN,RGL1,ANKRD12,CAMTA1,TCF4,SATB2,TCF12,SIRT1,FLRT2,TMEM237,PRDM10,WNK3,RGS7BP,ST7" MicroRNA hsa-miR-1294:mirSVR_highEffct hsa-miR-1294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.18E-47 4.02E-43 2.85E-46 2.63E-45 128 775 "VWA5B2,KLHL32,BRAP,ADRB2,UNC79,PITPNM2,AMT,LRCH2,FGD2,PHYHD1,SPTBN4,ARRB2,ATP1B3,N4BP2L1,TTLL9,SEC11C,ARHGEF7,GYG2,SGCE,CACNA1B,KALRN,CAST,TIGD7,CHN2,EPS15L1,PLAA,TPP1,ARMC8,FAM149A,SLC4A8,AKAP12,SNCAIP,SEC24C,PDE4DIP,DZIP3,HDAC9,KATNAL2,ARHGAP24,LONRF1,LIN54,IST1,DGKG,MYEF2,SV2B,SPOCK3,CHRDL1,DMD,DTNA,AASDH,EDN1,EDNRB,OPTN,STARD3NL,C8orf37,EIF1,LRRC17,ADGRV1,FCGR1A,TMEM107,KHDRBS3,DISC1,ACSS1,LRRC37A6P,GCNT2,TTBK1,COPS8,ZNF782,CNTRL,DIDO1,LINGO1,HAS2,DDX19B,ARHGAP36,ACOT7,MSL1,IL6ST,CREG2,HECTD2,NCOA7,MAN2A2,MAT2A,MMP16,ZNF680,MSR1,MXI1,MYO9A,NEFM,NF1,NNAT,NTRK3,OPRL1,ZNF827,NLGN3,EPB41L4B,GRAMD1C,PRPSAP2,PTPRG,CEP97,NWD1,RADX,KHDRBS2,MSANTD2,RDX,GTDC1,FIGN,RGS3,KCTD17,GSTCD,ROBO1,CCDC102B,EPHA10,ATP8B4,ATAT1,SEC14L1,FHOD3,RCOR3,CLSTN2,SULF2,SYP,TRIM2,CLASP1,DICER1,MTMR14,TBC1D15,RBFOX3,ADAMTS9,UBE3B,NETO1" MicroRNA hsa-miR-4299:mirSVR_highEffct hsa-miR-4299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.75E-47 4.34E-43 3.08E-46 2.84E-45 124 729 "ABCF1,SLC24A4,ARHGAP20,BIN1,OGT,PKP4,SFMBT2,SEC11C,KSR1,JAZF1,BAIAP3,CCK,KRIT1,ENTPD6,MAGI1,TPP1,IQCK,FAM149A,SLC4A8,ZNF385A,GDA,CLIP3,SNCAIP,SEC24C,CSNK1G3,SOCS5,RIMS2,ARHGAP24,AIF1L,GIT2,ARMCX2,DMD,KLHL5,YAF2,MRO,KMT5B,GOLGA7,ASB3,STARD3NL,EPB41,RCAN2,GPHN,CLVS1,FAM198B,ZNF461,SCML2,FGF12,FGF14,FOLH1,NBEA,HHIPL1,ABLIM2,DISC1,NEU3,ADAM28,PPARGC1A,GLI2,RAB30,ZNF638,FERMT2,TDRKH,LPAR4,CLASRP,IRAK3,HNMT,KIF5A,HECTD2,PIK3AP1,XRRA1,COL28A1,MSR1,NRBP2,NTRK2,NUCB2,IGSF11,PDE4D,GPR85,GNG2,TMEM260,PTPRG,NKAIN1,TTC13,ZNF615,RAD51D,ZNF493,MSANTD2,RFX2,RORB,GLDN,CLIP1,SAFB,ATXN2,FOXRED1,ASAP3,SHC4,NLGN1,SLC11A1,TET1,TMCC1,BDP1,UHRF1BP1L,PBLD,ZSCAN29,NSFL1C,MCF2L,ADGRL3,SYNE1,RNF216P1,SLC44A1,TPM2,AMACR,CLHC1,CCDC136,ZNF781,KLC2,GUSBP1,CFAP298,ZNF540,ZSCAN26,PHTF2,CASC15,IFT88,NETO1,PRRT4" MicroRNA hsa-miR-1182:mirSVR_highEffct hsa-miR-1182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.93E-47 4.43E-43 3.15E-46 2.90E-45 115 628 "KCNH8,ABHD6,CC2D2A,ALCAM,GPRASP2,PHF12,SUGT1P4-STRA6LP-CCDC180,CASK,RNF182,BACH1,SEC11C,BLM,CACNA1G,CACNA2D1,CACNB4,KALRN,CAMK2G,CAST,NFS1,PRC1,MTMR7,C1orf52,DCLK1,ZMYM4,C7orf61,NRXN3,AKAP6,COL11A2,SLC4A8,COX4I1,FAM171B,CLIP3,TRIM69,ARHGEF10,HDAC9,HDAC4,PITPNC1,ACOT8,YAF2,PHF20L1,RCAN2,ETV1,TAOK3,GTF2IRD2,HPCAL4,TPPP3,ERAP1,FREM1,COPS8,AIFM3,ZNF638,CBX1,PLCD4,ZNF496,RNFT2,IRAK3,RASSF8,ZHX1,NCKAP1L,HMGCL,NEGR1,MYLK2,RBPJ,IL6R,BLOC1S2,ADAM22,OCRL,OXTR,OLA1,RETREG1,PRPH,RELN,PTPRG,PTPRO,ZSCAN2,NWD1,OXR1,RBBP6,RGS4,BAALC,NCBP3,SEMA6D,PRCD,MRAS,ARX,NUBPL,PPP4R3A,DHX30,SLC14A1,BTBD7,SLC22A4,RCOR3,TTC17,SYNE2,VPS13A,SYPL1,MTCL1,DNMBP,TEK,MTMR14,ASXL3,KAT6B,ZNF346,TTC3,EIF4ENIF1,GORASP1,WNT7A,CLDND1,NDRG4,MKRN3,SLC30A4,ADAMTS9,SLC17A7,WNK3,FAM13C" MicroRNA hsa-miR-520f-3p:TargetScan hsa-miR-520f-3p TargetScan 8.97E-47 5.02E-43 3.56E-46 3.27E-45 102 492 "ABR,ADD1,MTUS1,HECW2,KCTD16,OSBPL8,PCDH10,ANK2,APBB2,EIF4G3,ATP2B2,DST,ARHGEF7,MTMR3,JAZF1,MYRF,PTBP2,PRC1,CDC25B,CDH2,MAGI1,CFL2,ARMC8,LETMD1,IGDCC3,CLOCK,GREB1,RASSF2,DGKB,ABCC5,EDNRB,FSD1L,MBNL2,PLXNC1,PAN3,EMX2,ERBB4,DNAJC27,EZH1,MED12L,POLK,FLT1,MSANTD4,GLUL,MAP7D2,LUZP2,GPR37,PTPRT,FAM222A,BACH2,RBPJ,IL6ST,KCNB1,MARK1,MBNL1,MEF2C,MXI1,NFYA,NOVA1,NPTX1,OCRL,GPR137C,PDE3A,CCSER2,LRP12,PPP3CA,PKIA,APTX,PTPRD,RDX,FIGN,ALG9,CYB561D1,RXRA,ATXN7,MYO18A,FNDC3A,EPC1,ARHGAP26,IQSEC2,CDK19,LMO3,NXT2,RGL1,ARHGEF9,PLCB1,ANKRD12,FBXW11,CUX2,NSD1,PIK3R5,RGMB,NR2C2,RICTOR,LYPD6,LAMP5,CADM2,PRDM8,PRDM10,FAM13C,ADAMTSL3,NETO1" MicroRNA hsa-miR-302c-3p.2:TargetScan hsa-miR-302c-3p.2 TargetScan 8.97E-47 5.02E-43 3.56E-46 3.27E-45 102 492 "ABR,ADD1,MTUS1,HECW2,KCTD16,OSBPL8,PCDH10,ANK2,APBB2,EIF4G3,ATP2B2,DST,ARHGEF7,MTMR3,JAZF1,MYRF,PTBP2,PRC1,CDC25B,CDH2,MAGI1,CFL2,ARMC8,LETMD1,IGDCC3,CLOCK,GREB1,RASSF2,DGKB,ABCC5,EDNRB,FSD1L,MBNL2,PLXNC1,PAN3,EMX2,ERBB4,DNAJC27,EZH1,MED12L,POLK,FLT1,MSANTD4,GLUL,MAP7D2,LUZP2,GPR37,PTPRT,FAM222A,BACH2,RBPJ,IL6ST,KCNB1,MARK1,MBNL1,MEF2C,MXI1,NFYA,NOVA1,NPTX1,OCRL,GPR137C,PDE3A,CCSER2,LRP12,PPP3CA,PKIA,APTX,PTPRD,RDX,FIGN,ALG9,CYB561D1,RXRA,ATXN7,MYO18A,FNDC3A,EPC1,ARHGAP26,IQSEC2,CDK19,LMO3,NXT2,RGL1,ARHGEF9,PLCB1,ANKRD12,FBXW11,CUX2,NSD1,PIK3R5,RGMB,NR2C2,RICTOR,LYPD6,LAMP5,CADM2,PRDM8,PRDM10,FAM13C,ADAMTSL3,NETO1" MicroRNA hsa-miR-124:mirSVR_highEffct hsa-miR-124:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.53E-46 8.58E-43 6.07E-46 5.59E-45 154 1105 "PLEKHH1,ZNF608,RTL9,OSBPL8,CC2D2A,TAOK1,SEMA6A,ZNF687,LCORL,PPP4R4,ARHGDIA,ASPA,ATP1A1,ATP2B2,LINC00847,BCL7A,NRP2,MYRF,KALRN,PTBP2,USP2,CDH2,LHX2,QKI,CNTN1,AKAP6,RTTN,CLOCK,ANKRD44,SNCAIP,VCAN,SOCS5,HDAC9,GAPVD1,DAPK1,FBXL5,RHOBTB1,SPOCK3,EXOG,DNM1L,E2F5,SNX29,EDNRB,HIPK3,SEMA3D,FSD1L,STARD3NL,FER,PRKAG2,SUCO,SYNCRIP,POMT1,ZNF605,GABRG2,IQGAP2,DISC1,KIAA1841,ARFIP1,GDF9,PCDH17,GHR,CRCP,RAB30,KIAA1958,GPT2,GPD2,GRIA2,GSN,KAT7,AP4S1,SOX21,IRAK3,MYLK2,IL6R,ITGA7,SLC35G1,KIF2A,LIMS1,PAXBP1,HECTD2,ASPRV1,MARK1,MAT2A,MBNL1,POC1B,MITF,NFE2L2,NME4,NRCAM,PCDH8,PCDH9,PDE4B,GNG2,PIK3C2A,RETREG1,JAKMIP1,SMOX,ING3,SH3KBP1,MTMR10,SPDL1,TMEM260,PTPRB,PTPRD,C1orf109,ACSS3,RAD17,RGS12,SLC25A36,SUGCT,GSTCD,CCDC25,ELP2,NEK11,ATP8B4,RYR3,SEMA6D,SCN7A,CASC3,GALNT10,SGK1,SH3GL3,SHC4,FAM81A,ATF7IP,TET1,ZKSCAN3,ZNF667,TTC17,LIMCH1,BDP1,ZC3H13,ITPRID2,KANK1,PLCB1,SYPL1,PCDHGA11,PCDHA5,C9orf85,UBE3A,USP1,WIPF1,CLDND1,FSTL5,EML6,ZNF189,SMARCAD1,EVI5,SEMA3B,PHTF2,CASC15,JMJD1C,FXR1,CPNE4" MicroRNA hsa-miR-92a-2*:mirSVR_highEffct hsa-miR-92a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-46 9.95E-43 7.03E-46 6.48E-45 130 805 "KDM5D,ADD1,ADD2,PTCHD1,LRFN2,AP2A2,SPOP,MARCH4,OGT,PI16,SUGT1P4-STRA6LP-CCDC180,CDK10,PRX,ARRB1,CDK13,MARCH3,ATP2B2,SLC2A11,N4BP2L1,MPDZ,ARHGEF7,CACNA1G,KALRN,RUNX1T1,PRC1,P2RX6,ENTPD2,NUMBL,CFL2,TAOK2,PPT2,TPP1,CNTN1,COL4A5,C1QL2,CTH,PUM1,ARHGAP32,CENPL,SPOCK2,IP6K1,GIT2,DBN1,DCTN1,C2CD2L,GSDME,DDX46,POM121,KIF19,DMPK,DPP6,PHC2,FCF1,APH1A,MBNL2,C3orf18,TMEM35A,RABEPK,SRRM1,EYA1,TAOK3,ZNF589,SPSB4,TMEM107,PRELID3A,GALC,B4GALNT1,IQGAP2,SRCAP,RUNDC3A,RNPS1,GLI2,TNRC6A,GLUL,TDRKH,STMN2,CLASRP,RABL2A,FAM222A,ATXN2L,SMAP1,LRRC25,RBPJ,LRRTM1,KIF5A,L1CAM,LAMP2,HECTD2,ZFYVE27,MAT2A,MEIS2,GIT1,MYO7A,RTL5,NF1,IGSF11,CDK18,PLTP,MAPKAP1,SH3KBP1,MAPK3,KLK6,ZSCAN32,PTPRH,CCDC40,ROGDI,ZDHHC4,KCTD17,RPE,NEK11,CASC3,FAM81A,NAPB,ZSWIM8,SPTB,IQSEC2,SEPT3,SYN1,CAMTA1,PCDHB15,SLC19A3,ARHGAP9,CLDND1,ZSCAN26,ANKS1B,PRTFDC1,HPS4,PCBP4,ST7,NHSL1" MicroRNA hsa-miR-628-3p:mirSVR_highEffct hsa-miR-628-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-46 1.00E-42 7.08E-46 6.52E-45 132 829 "KDM5D,KLHL32,KCTD16,CEP126,FAM135A,LRCH2,ARNTL,RGS20,DPY19L3,BMPR1B,SYNJ1,BTK,CALB1,PTBP2,ZNF501,LRBA,SEPT7,CLGN,ABCG2,CNN3,COL9A1,CREM,IPCEF1,CTH,GAPVD1,RIPOR2,LIN54,DYNC1I1,EDNRA,FRY,FSD1L,YAF2,TENM1,VPS13B,ENPP6,EXTL2,SH3YL1,CEP78,GORAB,POLK,SYNCRIP,SMC2,TPK1,ATP6V1H,KHDRBS3,CHL1,KIAA1841,GHR,HTATSF1,RABL2A,FRMD5,MIER3,NEGR1,ZIC5,SLC35G1,KCNN2,STXBP5,LAMP2,SYTL4,HECTD2,PACRG,CHIC1,MEF2C,MEIS1,ZNF680,PCDH9,PDE4D,EPB41L4B,PPM1B,PPP3CA,PRKACB,MAPK10,VPS13C,CNTLN,PTX3,PEX2,OXR1,RET,PBRM1,ALG9,CARF,CCDC102B,ATP8B4,GLDN,ADAL,ABCA11P,HUNK,ATAT1,RTN1,ZFP30,PPP4R3A,SLC8A1,ATF7IP,TET1,TTC17,CMTR2,MYCBP2,SPTB,ZC4H2,LARP4,NKAIN2,ELOVL4,SEPT3,SATB2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CCDC173,BHLHB9,STXBP4,HIRA,RPL7L1,FAM155A,UBE2H,ZNF708,ZNF17,LYPD6,FSTL5,SPIRE1,URM1,KCNAB1,FBXO36,RNF170,KLHDC1,NETO1,RNF146,SENP7" MicroRNA hsa-miR-220a:mirSVR_lowEffct hsa-miR-220a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-46 1.15E-42 8.15E-46 7.50E-45 112 601 "SMIM17,DPP10,MAP4K3,KCNAB2,MADD,ARRB1,PCDHGB4,EIF4G3,SLC2A11,N4BP2L1,ADAM23,DST,MTMR2,JAZF1,CALM1,RHBDL1,ZNF501,LDB2,LHX2,RAB33A,STOML1,CLTB,LETMD1,RBM39,ANKRD44,GDA,SLITRK5,PHF14,RUBCN,MYADM,KATNAL2,LONRF1,GIT2,KLHL3,RHOBTB1,APH1A,EIF4G2,DENND4A,SPEG,RRAGB,ARMCX1,DLC1,FCGRT,POLK,SUCO,WDR83,POMT1,TMEM107,CHL1,C15orf41,DISC1,GATM,SPIN1,DCLK2,GPT2,MCHR1,SOX21,PADI2,TNFAIP8L3,SMAP1,ZNF546,KCNJ5,MARK3,MYO7A,RTL5,NPTX2,PCDHGC3,PCDH9,GPR85,PFKFB3,ING3,POLG,PPARA,PCDHB17P,PRKACB,PTPRB,ZFHX4,RPS20,CLIP1,SEMA6D,ST8SIA1,RADIL,BDP1,SPP1,ERC1,UNC5B,ZC3H13,TTBK2,KANK1,FBXW11,ZFP90,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,CYB561A3,THRA,KAT6B,STXBP4,DCBLD1,TSC1,VLDLR,XRCC4,GAL3ST3,FAM198A" MicroRNA hsa-miR-4301:mirSVR_lowEffct hsa-miR-4301:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-46 1.35E-42 9.53E-46 8.77E-45 143 967 "RALGAPA1,ACADM,AS3MT,TMEM132B,PSMG3-AS1,TMCC3,ADD1,BRAP,PWWP2A,DPP10,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,BCAS1,SPTBN4,NUMB,RASL11B,ATP1A3,SLC4A4,NAE1,C5,CA8,THSD7A,SLC25A14,HIP1R,CBLN1,MTMR7,SLIT2,C7orf61,FBXO7,MAP4K4,ZFP28,CRY2,ABCG1,SOCS5,PDE4DIP,KIAA0040,CYBB,ARHGAP24,MATR3,MYEF2,MFAP3L,KIAA0319,GSDME,SPOCK3,CPEB2,ABCC5,DNM1L,E2F5,EDNRB,RASGRP1,VPS13B,FCGR1A,FCGR3A,FLYWCH1,ATP6V1H,CSPG5,AP4B1,FYB1,GABRG1,GALC,DISC1,LRRC37A6P,CPLX2,GCNT2,SULT1C4,MSTN,GGTA1P,TNRC6A,CBX1,STON1,FAM19A2,AGBL5,TCEAL6,ZNF181,ITGAM,KCND1,L1CAM,SYTL4,MEIS1,MXI1,NEK1,NF1,DNHD1,NPTX2,SMIM11A,OCRL,CLDN11,GLIPR1L2,DPY19L2P2,PDE3A,ENPP2,PFKFB4,SNX10,PNMA3,STRN3,LRP12,PPP2R5E,PKIA,MAPK9,PTCH1,ANKHD1,PTPRO,PID1,USP47,OXR1,GTDC1,RFX3,SLC25A36,RNASEL,TMLHE,ROBO1,PCMTD2,EPHA10,CASC3,FERMT1,HKDC1,CHD9,FBXO11,FNDC3A,SEC31A,SLC2A5,SLC6A11,NAPB,IFT122,ANKRD36,SOX3,ZNF423,SPTAN1,NFASC,ITPRID2,NKAIN2,NECAB1,ADGRL3,PCDHGB7,C18orf54,SLC44A1,DCBLD1,UBE3A,MEIS3,HNRNPA3,CASC15,TRAM2-AS1" MicroRNA hsa-miR-330-3p:TargetScan hsa-miR-330-3p TargetScan 2.58E-46 1.44E-42 1.02E-45 9.36E-45 124 737 "C3orf14,KLHL32,ADD2,HECW2,KCTD16,ARHGAP20,CARNS1,GPRASP2,CDC42BPA,APBB2,APC,ATP2B2,BACH1,NRP2,FUBP1,MTMR3,MYRF,LDLRAD4,CA12,CALM1,CBFA2T2,C1orf52,CDH2,NRXN3,IGLON5,PCYT1B,FAM171B,ARHGEF10,CSNK1G3,APPL1,GAPVD1,MAML1,IP6K1,DNAL1,PITPNC1,JAKMIP2,ELMO1,FAM107B,DLX1,DRP2,RCAN1,EBF1,PHC2,HEYL,MBNL2,ING4,RCAN2,MTSS1L,ERBB4,PTK2B,PPP1R1B,MED12L,FGFR1,HPCAL4,AGAP2,DCTN2,CELF1,NSG1,GABRA3,RAPGEF6,GLYR1,GPR75,PRUNE2,GPR37,RNF165,RASSF8,HAS2,DDX19B,MIER3,IL6R,KLHL23,L1CAM,ASPRV1,MARK1,MAT2A,PPM1L,AFF1,PDE1B,PFKFB3,LRP12,KANSL1,PRKAB2,MAPK10,DIRAS2,NKAIN1,RIC8B,LGI2,RORB,MCMBP,RXRA,CCDC112,S100B,ATXN7,HSPA4L,PPM1E,FNDC3A,NAPB,EPC1,COA1,KLHL7,PCDHB15,NSD1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CBX5,ASXL3,BHLHB9,BCL2L13,MICU3,REEP1,DPYSL5,PRTFDC1,PRDM8,ITM2C,PARP11,FZD3,JPH3" MicroRNA hsa-miR-187:mirSVR_lowEffct hsa-miR-187:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.03E-46 1.70E-42 1.20E-45 1.10E-44 122 715 "DGCR6,GALNT13,CC2D2A,HFM1,CARNS1,ANK2,SUGT1P4-STRA6LP-CCDC180,PPFIA3,LGR5,SHROOM2,TMEFF1,STK33,DPY19L3,MIR9-3HG,ARHGEF7,GYG2,CBS,METTL6,USP6,CBFA2T2,CDH2,CHGB,PPT2,TBPL1,CRMP1,CLIP3,TRIM69,RGS6,SEC24C,ARHGEF10,UBXN2A,ARHGAP32,RIPOR2,ZFYVE16,EARS2,PLPPR4,TMCC2,DPP6,DTNA,EDNRB,SEMA3D,KLHL5,YAF2,TNK2,PAN3,DCTN4,EPB41,SLC43A2,ADGRV1,CLVS1,TMEM132C,ZMYND10,KAT8,SYNCRIP,FLNC,PSD2,EFCAB2,APOPT1,KHDRBS3,STAU2,HHIPL1,DOT1L,TVP23A,MEGF10,DISC1,LRRC37A6P,ZNF638,ELOVL5,ZNF491,RBPJ,INPP5B,A1BG-AS1,KTN1,LAMP2,LYPLAL1,MARK3,MBNL1,MEIS1,MYO7A,ALDH1L2,CNOT4,PCSK5,PRTG,PDE3A,TRHDE,EXOSC10,FA2H,PPP3CA,MAPK10,BCAS3,PIGG,ZIK1,CCDC40,ZFHX4,CCDC102B,SGK1,R3HDM2,WDR37,BTBD3,SEPHS1,PDZD2,IZUMO4,STAU1,CEP68,ANKRD28,PCDHA5,TEK,PMS2CL,TMPO,TPM1,UCHL1,FLRT2,PLEKHH2,ELFN1,MKRN3,PRTFDC1,NT5M,STOX2,RNF103,PDSS2,JMJD1C,GAN" MicroRNA hsa-miR-4260:mirSVR_highEffct hsa-miR-4260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.03E-46 2.25E-42 1.59E-45 1.46E-44 108 562 "XKR4,BRAP,ADRA1D,RTL9,ALCAM,ARHGAP20,AMT,FGD2,KCNAB2,EPB41L5,PHYHD1,TNRC6C,PPFIA3,SHROOM2,SFMBT2,ATP1A3,RNF182,BACH1,BTK,SCAPER,MYRF,RUNX1T1,USP2,SRSF11,SUMF2,ANKRD44,CLIP3,SEC24C,VCAN,TBC1D5,MYEF2,ZC3H11A,DDX46,POM121,SPOCK3,DNM1,DPP6,PHF20L1,EIF5,C8orf37,RCAN2,LRRC17,STX2,RAB9B,SIRPB1,F5,MED12L,POLK,FLT1,C2orf88,CELF1,MEGF11,TRAF3IP2,GATM,ALDH1L1,LOXL3,DIDO1,RNFT2,ATOH8,VSIG4,ELOVL5,AGBL5,IDH3B,MATN2,MSR1,NME4,SLC11A2,TBC1D25,GPR137C,SEMA5B,SNX10,PCDH18,POLG,FSD1,CASTOR1,NKAIN1,SLC25A48,SUSD4,FIGN,RIC8B,CARF,ATP8B4,DGLUCY,ASAP3,SEC31A,SLC6A11,ATF7IP,BDP1,PEG10,SEPT3,ARHGEF9,RNF216P1,THRA,MTMR14,CSMD1,TRIO,NUTM2A,GORASP1,OSBP2,P2RY12,ZNF540,LAMP5,HPS4,NAV3,NELFE,DOCK8,SMIM8,NETO2" MicroRNA hsa-miR-1258:mirSVR_highEffct hsa-miR-1258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.42E-46 2.47E-42 1.74E-45 1.60E-44 121 706 "KLHL32,AXIN2,BEND6,TBC1D14,WDR35,OSBPL8,ALCAM,LCORL,TNRC6C,ATP1B3,BID,GYG2,PTBP2,SRSF11,ARMC8,ZFP28,HAPLN1,ANKRD44,NCOR1,CSF1R,ARHGEF10,VCAN,DOCK4,KCTD8,DAPK1,SCRN1,GIT2,ARMCX4,PLPPR4,SGSM2,WDR20,ACOT8,ECM2,FRY,PHF20L1,EMX2,EPHB1,ERBB4,FCGRT,FGF1,FGF12,SEC23B,STAU2,SDCBP2,DISC1,GFRA2,CSDC2,PPARGC1A,RAB30,GPT2,TDRKH,CCDC184,GRIA2,PLCD4,ADAMTS6,GUCY1B1,FAM222A,LRRC25,RBPJ,KLHL23,KCNN2,CREG2,MBP,MMP16,MSI1,ZNF862,MYT1,NEK1,OCRL,PCSK1,GNG2,NALCN,PMP22,TRHDE,PSAT1,PPARA,PPP2R5E,RANBP3L,PTPRE,TMEM255A,ZNF493,RADX,GTDC1,ZFHX4,CARF,ABCA11P,SEC14L1,KIF21A,CHD9,CNKSR2,ZNF415,SPART,CLSTN2,DIP2A,SYT1,C12orf76,TCF12,DOCK9,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TIAM1,R3HDM1,TPM1,SGK3,FAM155A,UBE2H,UGT8,ZNF74,ZNF138,SMARCAD1,RNF103,ADAMTS9,FIP1L1,WNK3,SPATA13" MicroRNA hsa-miR-1909*:mirSVR_lowEffct hsa-miR-1909*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.37E-46 4.12E-42 2.90E-45 2.67E-44 143 976 "ADCY6,PLEKHH1,KCTD16,OSBPL1A,C1QTNF3,ARHGAP20,SYT13,CDC42BPA,VAT1L,CDK13,SLC2A11,DPY19L3,TTLL9,ADAM15,ADGRB2,MIR9-3HG,DNAJC27-AS1,NRP2,SYNJ2,MTMR2,AP1M1,SGCE,CACNB4,CAPN3,LDB2,SEPT7,ASIC3,NDST3,PPT2,STOML1,FAM149A,COL9A1,ABI3BP,ZNF385A,CS,RGS6,CSNK1E,OSBPL3,FAM131B,MYADM,ARMCX4,ZNF804A,POM121,SNAP91,WDR20,CD99L2,DMTF1,DNAJB6,ABCC5,DNM1L,PHC2,YAF2,IRAK4,ACSL4,ST3GAL6,FCGRT,FER,FGFR3,BAIAP2,FLT1,SLC37A3,GAD1,GFER,MAP7D2,TMEM121B,PCLO,SLC2A6,ZHX1,AGBL5,C9orf129,SHISA6,ICA1,MSL1,IL6R,TMEM240,KIT,LIMS1,CLEC18A,MAP4,MBD1,MBP,KITLG,SCAMP5,AFDN,LYRM9,MYO7A,ZC3H12B,SFR1,CNOT4,SLC11A2,OPA1,ZNF827,DPY19L2P2,PCSK5,GPR85,NLGN3,PIK3R1,ING3,SH3KBP1,KANSL1,PRODH,CNNM2,NDUFS7,ZIK1,PTPRO,FAT4,RBBP8,GTDC1,UBR7,KCNIP3,SBF1,CSRNP3,ATXN2,ATXN7,SLA,WDR47,ZNF430,SLC8A1,SNRPN,DDN,CLASP2,ZC4H2,SYT1,ANKRD28,FBXW11,SYNE1,CDH22,TLR4,PIK3R5,RGMB,TRIO,UGT8,OSBP2,CCDC14,ZNF711,ATP6V0E2,SPHK2,POLR3H,UPF3A,SEMA3B,FBXO36,NLRP3,RNF170" MicroRNA hsa-miR-576-5p:PITA hsa-miR-576-5p:PITA_TOP PITA 8.60E-46 4.81E-42 3.38E-45 3.11E-44 95 434 "FMNL2,CCDC85A,PCDH19,HACE1,SRPX,DPP10,EPB41L5,PPP4R4,SLC4A4,DOCK11,MPDZ,CA8,CLGN,QKI,MAP4K4,ARMC8,ABI3BP,CNTNAP2,ERC2,KIAA0408,DGKB,RHOBTB1,WDR20,RAB39B,CPEB2,ANKRD46,TENM1,ERBB4,CLVS1,FGF1,SUCO,AFF2,TMEM107,MEGF11,PCDH17,TOX3,FUT10,GRB10,SOX21,ZHX1,HNF4G,NEGR1,IGF1,ZIC5,MAP2,MBNL1,MYO5A,NCAM2,CNOT4,CNTN3,CCSER2,XRN1,PLCL1,PKIA,PTCH1,PTPRE,USP47,RFX2,UBR7,ZFHX4,ZNF532,RYR3,TRA2B,ZFP30,CHD9,FNDC3A,WDR47,SP4,ARHGAP26,ITPRID2,LARP4,KLHL7,NECAB1,ANKRD28,ZEB1,RPGRIP1L,PUM2,FRYL,AP4E1,ZNF106,RIMBP2,TP53BP2,STXBP4,LYPD6,ZBTB38,PRTFDC1,SLC38A1,WNK3,PDSS2,RGS7BP,DNAH10,KAT6A,HNRNPA3,SOCS4,SENP7" MicroRNA "AATGTGA,MIR-23B:MSigDB" "AATGTGA,MIR-23B:MSigDB" MSigDB 8.72E-46 4.88E-42 3.43E-45 3.15E-44 91 396 "MTUS1,PCDH19,OSBPL8,ARHGAP20,PKP4,PPP4R4,NCOA1,SLC4A4,SYNJ1,RUNX1T1,CCK,CCNH,CBFA2T2,MAGI1,DLGAP2,SOCS6,NRXN3,CLCN3,QKI,MAP4K4,COL4A5,COL11A2,AKAP12,LRIG1,CSNK1G3,PLCXD3,MAML1,POM121,WDR20,DLX1,CPEB2,EGR3,TNK2,ETV1,EYA1,PTK2B,SPSB4,SUCO,ARFIP1,PPARGC1A,GLYR1,TNRC6A,ADAMTS6,HAS2,HNF4G,IL6R,KCNK3,IPO5,PAXBP1,MAT2A,MEF2C,MEIS1,MEIS2,KITLG,AFF1,MSI1,PRTG,PDE4B,ZNF655,ING3,PPP2R5E,PKIA,ANKHD1,ROBO2,SNX22,SEMA6D,SATB1,ZFP2,SEC14L1,SGK1,AMBRA1,FBXO11,BTBD7,CPEB4,SOX11,ZNF423,NKAIN2,SEPT3,CAMTA1,ATMIN,SATB2,PUM2,NACC2,TMPO,WBP2,TBC1D15,VSNL1,ZIC1,MICU3,PRDM10,WNK3" MicroRNA "AATGTGA,MIR-23A:MSigDB" "AATGTGA,MIR-23A:MSigDB" MSigDB 8.72E-46 4.88E-42 3.43E-45 3.15E-44 91 396 "MTUS1,PCDH19,OSBPL8,ARHGAP20,PKP4,PPP4R4,NCOA1,SLC4A4,SYNJ1,RUNX1T1,CCK,CCNH,CBFA2T2,MAGI1,DLGAP2,SOCS6,NRXN3,CLCN3,QKI,MAP4K4,COL4A5,COL11A2,AKAP12,LRIG1,CSNK1G3,PLCXD3,MAML1,POM121,WDR20,DLX1,CPEB2,EGR3,TNK2,ETV1,EYA1,PTK2B,SPSB4,SUCO,ARFIP1,PPARGC1A,GLYR1,TNRC6A,ADAMTS6,HAS2,HNF4G,IL6R,KCNK3,IPO5,PAXBP1,MAT2A,MEF2C,MEIS1,MEIS2,KITLG,AFF1,MSI1,PRTG,PDE4B,ZNF655,ING3,PPP2R5E,PKIA,ANKHD1,ROBO2,SNX22,SEMA6D,SATB1,ZFP2,SEC14L1,SGK1,AMBRA1,FBXO11,BTBD7,CPEB4,SOX11,ZNF423,NKAIN2,SEPT3,CAMTA1,ATMIN,SATB2,PUM2,NACC2,TMPO,WBP2,TBC1D15,VSNL1,ZIC1,MICU3,PRDM10,WNK3" MicroRNA hsa-miR-93*:mirSVR_highEffct hsa-miR-93*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.43E-46 5.28E-42 3.70E-45 3.41E-44 143 978 "NDRG3,KLHL32,OGT,SUGT1P4-STRA6LP-CCDC180,TNRC6C,SLC4A4,N4BP2L1,SEC11C,SYNJ1,ARHGEF7,PTBP2,RUNX1T1,SCARB1,TIGD7,MYL6B,NGEF,COL11A2,AKAP5,CPS1,GALNT9,PPP1R16B,UBXN2A,DOCK4,DCAF8,EARS2,DDX46,SPOCK3,USP3,NR1D2,CPEB2,EDN1,ANKRD46,MBNL2,KMT5B,PLEKHA1,PAN3,EPHB1,DNAJC27,NRN1,FCGR1A,FER,SUCO,IQCG,NOP56,NELFCD,STAMBP,ERGIC3,GAD1,ALDH1L1,SESN1,ZNF276,MSL3,ZNF638,STON1,GRIA2,FAM19A2,SLC2A6,MIER3,IL6ST,ZNF678,KCND2,STXBP5,HECTD2,PACRG,MBP,MEIS1,MYCN,NF1,DNHD1,NTRK2,TBC1D25,CNTN3,PCSK1,PCSK5,CDK18,GPR85,OLA1,NALCN,STRN3,ING3,MBOAT7,SH3KBP1,PPM1B,SNRK,PTPRB,CEP97,TMEM255A,RAD17,CCDC40,RASGRF2,RBBP6,MORC4,NUDT11,NEK11,ATAT1,SEMA6D,SUPT20H,ASAP3,DZIP1,PREX2,SEPHS1,BTBD7,GKAP1,OGDHL,MYH15,ANKRD36,SNCA,SNRPN,USP33,DOP1A,TRERF1,BDP1,ZSWIM8,GLT8D1,KDM4C,ZC3H13,PBLD,SSTR1,RGL1,PHLDB1,NECAB1,NUDT10,COBL,SYT5,ZEB1,FRYL,SIRT1,ZMAT3,TLR4,TMPO,TNS1,SYNPO2,DCBLD1,KCNE5,SGK3,RICTOR,XRCC4,ZFP37,ZNF189,ANKS1B,CADM2,UBE3B,LAS1L" MicroRNA hsa-miR-876-3p:mirSVR_highEffct hsa-miR-876-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-45 1.13E-41 7.91E-45 7.28E-44 124 751 "KCNH8,SLC24A4,HACE1,KIAA1324,LTBP4,FAM135A,LGR5,STX16,RGS9,CALM1,CAMK2G,DGKI,TIGD7,CHN2,QKI,FAM149A,COL4A5,SIPA1L1,PLXNA4,APPL1,PHF14,GREB1,ZSCAN23,ZC3H11A,ALKBH8,DMD,SLC25A18,TOM1,ANKRD46,KLHL5,PHF20L1,APH1A,EGFR,MBNL2,PLEKHA1,ELN,EPHB1,ST3GAL6,FCGR3A,ZSCAN30,KAT8,GORAB,FGF12,FOXF2,RGPD5,NSG1,OGA,GABRA3,BRD8,DBF4,GRIN2C,CIT,FAM107A,LRRCC1,IL6R,NME9,SLC35G1,KCND2,KCNN2,LIMS1,NCOA7,MEIS1,NUCB2,GLIPR1L2,PDCD2,GNG2,FAM216A,PLIN1,SLC25A23,PURG,TATDN3,RANBP3L,PRKACB,MASP1,BCAS3,WBP1L,TMEM260,PTPRD,PEX2,CCDC40,SH3TC2,ZCWPW1,RBBP6,RDX,ZMAT4,KCNIP1,ATXN7,SCN8A,SMPD3,GALNT10,COPZ1,SGK1,ST6GAL1,SLA,SLC14A1,ZFP1,ANKRD36,SNAP25,SNRPN,PDZRN3,KDM4B,TEX2,NFASC,PBLD,POGZ,ITPRID2,KANK1,SYNE2,SYP,SLC37A2,CLASP1,PCDHB3,FAM200B,SLC44A1,ERCC6L2,NPL,PDSS1,PPIL6,UBTF,USP1,CFAP298,PCBP1-AS1,MFF,NAV3" MicroRNA hsa-miR-449c*:mirSVR_highEffct hsa-miR-449c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-45 1.36E-41 9.54E-45 8.78E-44 109 583 "RALGAPA1,HECW2,TXNDC16,ALCAM,ABCD2,DPP10,VAT1L,TNRC6C,PRX,RGS20,ATP1B3,ADGRB3,PTBP2,USP6,CDH2,LRRFIP1,QKI,SLC4A8,ABI3BP,ZFP28,CRHBP,PDE4DIP,DOCK4,GPRASP1,TBC1D5,KIAA0586,IST1,DDX46,GRIN3A,DNAH9,DTNA,MAMLD1,DNM1L,EDNRA,FCF1,EIF5,DCTN4,F8,CEP78,FER,POLK,CELF1,CHL1,RAB30,ZNF638,FERMT2,ATP2B1-AS1,HNMT,KCNN2,KIF2A,STXBP5,CHIC1,LRP1B,MMP16,NF1,OGG1,LOC100128398,ZNF713,OXTR,PDE1C,SERPINI1,JAKMIP1,MINDY2,LRRN3,PPP2R5E,GRAMD1C,MTMR10,ELOVL2,TMEM260,KHDRBS2,RFX3,RGS12,RORB,ARMH4,FNIP1,SH3GL3,FBXO11,CNKSR2,NLGN1,NUBPL,SLA,MTERF2,RCOR3,SNCA,SNRPN,NXT2,ADHFE1,SEPT3,KLHL7,CAMTA1,ALG1,ADGRL3,ZEB1,TRIM2,RPGRIP1L,SYNE1,NR2E1,WBP2,TRO,STXBP4,TTTY15,PRR18,XRCC4,ZNF74,LYPD6,FSTL5,ZSCAN26,LAMP5,RNF103" MicroRNA hsa-miR-99a*:mirSVR_lowEffct hsa-miR-99a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-45 1.38E-41 9.66E-45 8.89E-44 106 551 "CLK4,NCKAP5,PWWP2A,FAHD2CP,CC2D2A,SRPX,CARNS1,SUGT1P4-STRA6LP-CCDC180,UPRT,CDK10,TMEFF1,PDE8B,ZBTB10,BARD1,BCHE,RAB29,KALRN,PTBP2,L3MBTL4,LHX2,WHRN,COL9A1,CSNK1E,OSBPL3,SOCS5,RASGEF1C,PUM1,CYBB,KCTD8,SCRN1,MED12,DNM1L,EDN3,HIPK3,SRRM1,TAOK3,ZNF589,PRKAG2,APOPT1,STAMBP,STAU2,CHL1,TRAF3IP2,FAM120B,CPLX1,GGT7,GLYR1,ZNF638,CLASRP,HLF,AGBL5,HP,IL6R,KCNN3,KIT,MSR1,LYRM9,FXYD7,NCAM2,NELL2,NF1,NOVA1,NUCB2,PDE4A,ENPP2,JAKMIP1,EPB41L4B,FA2H,MAPK4,VPS13C,CNTLN,TMEM260,TRIM68,FIGN,SCP2,HSPA4L,ARX,CPEB3,CHD9,FNDC3A,EPN2,PKNOX2,SNRPN,PBLD,ITPRID2,THSD1,PRRC2C,CAMTA1,TAL1,TPCN2,TRIM2,SYNE1,DOCK9,CCDC173,R3HDM1,SSBP2,CCDC14,CLIP2,VPS35L,SEMA3B,PPP1R3F,KCNAB1,KAT6A,PHTF2,SOCS4,JPH3" MicroRNA hsa-miR-4330:mirSVR_highEffct hsa-miR-4330:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-45 1.45E-41 1.01E-44 9.34E-44 123 741 "RALGAPA1,KCNH8,NDRG2,PTCHD1,ALCAM,OGT,ANK2,NUMB,DST,ST3GAL5,PTBP2,VXN,CAST,CLDN10,LDB2,CBFA2T2,LRRFIP1,TAOK2,QKI,ARHGEF6,IQCK,BAG4,FAM171B,CLOCK,CREM,CS,CSF1R,PHF14,USP6NL,HDAC9,MATR3,PITPNC1,PLPPR4,ECM2,ABCC5,GOLT1B,PHF20L1,PLEKHA1,RCAN2,VPS26C,EYA1,F8,RACK1,ZSCAN30,GORAB,FGF13,FGFR1,EFCAB2,UFM1,STAMBP,TRAF3IP2,DISC1,SESN1,PPARGC1A,LYVE1,COPS8,LPAR4,FAM222A,IRAK3,HNF4G,IL12A,ZNF678,INSM1,LRRTM1,KCNJ16,STXBP5,MEF2C,NOVA1,DNHD1,CLDN11,CNTN3,ENPP2,GPR85,PIK3R1,RETREG1,CCDC144B,PRKACB,GRAMD1C,HYDIN,PTN,PTPRB,RGS12,SLC25A36,NUDT11,PBRM1,RNASEL,ROBO2,ARMH4,SPIN3,CLIP1,NCBP3,TRAPPC13,WDR37,DHX30,INTS9,ANKRD36,SP4,MCF2L2,KLHL7,COBL,SIN3B,SYNE1,PCDHB10,PCDHB7,ARL10,MTMR14,RUNDC3B,PRR18,UBE2H,ZNF709,KLC2,XRCC4,ZNF19,TRIM9,ZXDA,STOX2,FIP1L1,WNK3,PDSS2,RTN4,RNF170,FXR1,NETO1" MicroRNA hsa-miR-506:mirSVR_highEffct hsa-miR-506:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.84E-45 1.59E-41 1.11E-44 1.02E-43 151 1091 "AXIN2,PLEKHH1,ZNF608,OSBPL8,CC2D2A,TAOK1,SEMA6A,ZNF687,LCORL,PPP4R4,ASPA,ATP1A1,ATP2B2,BCL7A,NRP2,MYRF,KALRN,PTBP2,USP2,CDH2,LRRFIP1,LHX2,QKI,CNTN1,AKAP6,RTTN,CLOCK,ANKRD44,SNCAIP,VCAN,SOCS5,HDAC9,GAPVD1,DAPK1,FBXL5,RHOBTB1,SPOCK3,EXOG,CPEB2,DTNA,E2F5,SNX29,EDNRB,HIPK3,SEMA3D,FSD1L,ADGRV1,CEP78,ZNF589,FER,PRKAG2,SUCO,SYNCRIP,POMT1,ZNF605,IQGAP2,DISC1,KIAA1841,ARFIP1,GDF9,PCDH17,GHR,CRCP,RAB30,KIAA1958,GPT2,GPD2,GRIA2,GSN,KAT7,AP4S1,IRAK3,MYLK2,IL6R,ITGA7,SLC35G1,KIF2A,LIMS1,PAXBP1,HECTD2,ASPRV1,MARK1,MAT2A,MBNL1,POC1B,MITF,AFDN,NFE2L2,NME4,NRCAM,PCDH8,PCDH9,PDE4B,GNG2,PIK3C2A,RETREG1,SMOX,ING3,SH3KBP1,MTMR10,SPDL1,TMEM260,PTPRB,PTPRD,C1orf109,ACSS3,RAD17,RGS12,SLC25A36,SUGCT,GSTCD,CCDC25,ELP2,ATP8B4,RYR3,SEMA6D,SCN7A,CASC3,GALNT10,SGK1,SH3GL3,SHC4,FAM81A,ATF7IP,TET1,ZKSCAN3,ZNF667,TTC17,LIMCH1,BDP1,ITPRID2,KANK1,PLCB1,SYPL1,PCDHGA11,PCDHA5,C9orf85,UBE3A,USP1,WIPF1,CLDND1,FSTL5,EML6,ZNF189,SMARCAD1,EVI5,SEMA3B,PHTF2,CASC15,JMJD1C,FXR1" MicroRNA hsa-miR-3192:mirSVR_highEffct hsa-miR-3192:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.10E-45 1.74E-41 1.21E-44 1.12E-43 132 850 "KCNH8,GALNT16,UNC5A,CDC42BPA,PI16,SUGT1P4-STRA6LP-CCDC180,MADD,ARRB1,LINC00173,MARCH3,N4BP2L1,CARMIL3,SEC11C,CFLAR,MYRF,CCK,CD86,PPT2,FBXO7,CNTN1,SLC4A8,CLIP3,TRIM69,CS,SNCAIP,RUBCN,CYBB,HDAC9,DCAF8,TMEM170A,HEPH,ALKBH8,GRIN3A,DNM1L,GOLT1B,WDPCP,ANKRD46,EGFR,GOLGA7,EPHB1,SRRM1,MRPL37,F8,TUBA1B,RACK1,FDFT1,PPP1R1B,FGF14,FGFR1,FOLR2,COQ5,USP21,STAU2,GALC,ERAP1,C15orf41,KIAA1841,ALDH1L1,TUBGCP4,ADAM28,GGT7,GHR,GLI2,TOX3,POLL,LOXL3,PRRC2B,PRUNE2,PCLO,GRIA2,CLASRP,RNF165,RABL2A,ATXN2L,HMGCR,AGBL5,ZNF678,LRRTM1,L1CAM,PAXBP1,MARK1,MAT2A,MEIS2,PPM1L,XRRA1,MT1M,MYO6,NF1,SLC11A2,PRTG,PDE4D,XRN1,SEPT4,WDR25,CNTLN,TMEM260,PPP2R3C,GAL3ST4,GTDC1,UBR7,EXD2,KIRREL1,CCDC25,FBXW7,SEMA6D,FNIP1,GALNT10,WDR47,ATF7IP,SNCA,LMO3,NKAIN2,SYN2,RPGRIP1L,HIF3A,ITGB3BP,AP4E1,C9orf85,TRO,MTCH1,CCDC14,TRIM9,LYPD6,ZNF138,STOX2,HPS4,GAL3ST3,PHTF2,ACTR3B,FRMD6,AP3B2,PRRT4" MicroRNA hsa-miR-32:PITA hsa-miR-32:PITA_TOP PITA 3.19E-45 1.79E-41 1.25E-44 1.15E-43 99 480 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-424*:mirSVR_highEffct hsa-miR-424*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-45 2.32E-41 1.62E-44 1.49E-43 113 630 "KCNH8,ACADM,CCDC85A,GALNT13,USP31,DPY19L2P4,OSBPL6,ABCD2,FAM131A,CASK,SLC4A4,DPY19L3,IL33,CALM1,NUMBL,CHN2,FHL5,CNTNAP2,PUM1,USP6NL,ARHGAP32,GSDME,POM121,ANKRD46,KLHL5,YAF2,CELSR3,FAM13A,KMT5B,KCTD3,PAN3,STX2,SRRM1,IGSF6,DNAJC27,TUBB3,GORAB,MED12L,OLFM1,SUCO,MEX3B,FOXF2,RGPD5,SMC2,CAMKK2,CELF1,CSPG5,DLL3,STAU2,SIGLEC8,LRRC37A6P,TXNL4A,RAB30,GPT2,GPR37,HECTD2,MARK1,MAT2A,SRSF12,KITLG,ZNF680,MSR1,NDP,NFIX,PNMA3,EXOSC10,PPM1B,CEP41,MASP1,PTX3,NUDT11,RNASEL,FBXW7,PTGR2,SEMA6D,CSRNP3,ST6GAL1,CABCOCO1,SPART,TROVE2,SSTR1,LARP4,NXT2,ELOVL4,KANK1,PLCB1,SYT1,PJA1,KLHL4,CUX2,PCDHGA11,FRYL,THRA,LRRC8A,FAM124A,TRIO,SSBP2,UGT8,PLEKHH2,CCDC14,XRCC4,ZBTB14,ZNF17,ZSCAN26,EMSY,MFF,TRIM16L,PCBP4,UBE3B,HNRNPA3,ADAMTSL3,KLHDC1,CPNE4" MicroRNA hsa-miR-558:mirSVR_highEffct hsa-miR-558:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.16E-45 2.33E-41 1.62E-44 1.49E-43 110 597 "CLK4,TBC1D14,AMPD3,MAGEE2,PPFIA3,RGS20,ARRB2,N4BP2L1,ADAM23,BBS2,ST3GAL5,SYNJ2,KALRN,MAGI1,TIGD7,SLIT2,HECTD1,SLC4A8,SLC35F1,CREM,HAPLN1,PDE4DIP,PLXNA4,ZSCAN23,DCAF4,C2CD2L,TMEM130,DDX46,SNAP91,SPOCK3,SLC29A4,NR1D2,DPYSL2,PDCD6IP,DNAJB6,ABCC5,C3orf18,EPB41L2,EPHB1,GMPR2,CLVS1,FLNC,NOP56,NELFCD,ATP2C1,CGREF1,SIGLEC8,WASHC2A,SESN1,LOXL3,DIDO1,ADAMTS13,AP4S1,ATXN2L,SYNPO,KCNH2,TTYH2,SYTL4,ZFYVE27,MAP6,MEIS1,PTOV1,MXI1,MYT1,DNHD1,NPR2,PDE4B,ZNF655,XRN1,EXOSC10,RETREG2,HYDIN,WDR25,PTPRE,ERI2,UBR7,RGS3,ATP8B4,ADAL,KCNIP1,KIF21A,SEPHS1,MYO16,ZNF423,ZSCAN29,SEPT8,ADHFE1,STXBP1,SYT5,CAMTA1,ZFP90,RPGRIP1L,CYB561A3,ZFPM2,ITGB3BP,PIK3R5,TPM1,MTCH1,RBFOX3,WIPF1,ZNF23,SLC30A3,VPS35L,EPM2A,UBE3B,KAT6A,AP3B2,LAS1L,SENP7,JPH3" MicroRNA hsa-miR-129-1-3p:TargetScan hsa-miR-129-1-3p TargetScan 4.43E-45 2.48E-41 1.72E-44 1.59E-43 86 357 "FMNL2,ADD2,KLHL13,CASKIN1,NCOA1,BCL7A,FUBP1,CACNA1I,MYRF,CACNA1B,CACNB4,CCNT1,DGKI,DLGAP2,NUMBL,RCBTB2,HECTD1,AKAP5,RCHY1,FAM171B,SEC24C,PLXNA4,PLCXD3,CCDC144A,IP6K1,AIF1L,ELMSAN1,MYEF2,RHOBTB1,SACS,E2F5,PLXNC1,RGS17,RCAN2,CEP85L,AKAP3,NBEA,CAMKK2,FUT9,MSANTD4,GABRG1,GPR75,CACFD1,GRIN2D,PRDM5,PTPRT,FRMD3,IGFBPL1,FAM69A,KCNB1,LIFR,PAXBP1,MAPT,MMP16,NEK1,GPR137C,PKIA,MAPK3,MAPK10,ELOVL2,RASGRF2,GTDC1,ROBO1,BAALC,RYR3,SEC14L1,ABLIM3,BTBD7,NMNAT2,ANKRD12,CLASP1,NSD1,GPRIN3,FRYL,NACC2,HEY1,FAM124A,FAM155A,FLRT2,RBFOX3,RICTOR,REEP1,HPS4,NAV3,PHTF2,FBXO36" MicroRNA hsa-miR-129-2-3p:TargetScan hsa-miR-129-2-3p TargetScan 4.43E-45 2.48E-41 1.72E-44 1.59E-43 86 357 "FMNL2,ADD2,KLHL13,CASKIN1,NCOA1,BCL7A,FUBP1,CACNA1I,MYRF,CACNA1B,CACNB4,CCNT1,DGKI,DLGAP2,NUMBL,RCBTB2,HECTD1,AKAP5,RCHY1,FAM171B,SEC24C,PLXNA4,PLCXD3,CCDC144A,IP6K1,AIF1L,ELMSAN1,MYEF2,RHOBTB1,SACS,E2F5,PLXNC1,RGS17,RCAN2,CEP85L,AKAP3,NBEA,CAMKK2,FUT9,MSANTD4,GABRG1,GPR75,CACFD1,GRIN2D,PRDM5,PTPRT,FRMD3,IGFBPL1,FAM69A,KCNB1,LIFR,PAXBP1,MAPT,MMP16,NEK1,GPR137C,PKIA,MAPK3,MAPK10,ELOVL2,RASGRF2,GTDC1,ROBO1,BAALC,RYR3,SEC14L1,ABLIM3,BTBD7,NMNAT2,ANKRD12,CLASP1,NSD1,GPRIN3,FRYL,NACC2,HEY1,FAM124A,FAM155A,FLRT2,RBFOX3,RICTOR,REEP1,HPS4,NAV3,PHTF2,FBXO36" MicroRNA hsa-miR-196b:mirSVR_highEffct hsa-miR-196b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.90E-45 2.74E-41 1.91E-44 1.75E-43 121 722 "BRAP,MAP4K3,APAF1,UPRT,TNRC6C,ARNTL,RASL11B,ATP2A2,DOCK11,RAB29,CALM1,PTBP2,CCPG1,PPT2,FAM19A5,QKI,MAP4K4,FAM149A,AKAP6,ABI3BP,TBPL1,TRIM69,DZIP3,PPP6R2,CYBB,BOC,HDAC9,GPRASP1,KIAA0586,KLHL3,SNAP91,RAB39B,EDNRB,MBNL2,EPB41L2,LRRC17,ZSCAN30,SLC9B2,GTF2IRD2,FHL1,RGPD5,ANKFY1,C2orf88,ATP2C1,SARAF,FYB1,GABRA3,GABRB3,GALC,DISC1,NEU3,GHR,TOX3,GRIA2,PRDM5,RNF165,PSIP1,DDX19B,NME9,MBNL1,LRP1B,POC1B,MYO9A,OPA1,P2RY1,PIK3C2A,ZNF655,XRN1,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R5E,RANBP3L,SNRK,WDR25,TMEM260,PTPRG,SH3TC2,ERI2,GTDC1,EXD2,C12orf49,ATP8B4,S100B,PRCD,FNIP1,CASC3,GALNT10,KIF27,HSPA4L,SLC12A2,SLC14A1,ELMO2,MYH15,MBD5,RBM34,TRERF1,HECW1,RBM26,DIP2A,KANK1,CAMTA1,SMG6,KLHL4,ZEB1,PUM2,MTMR14,ERCC6L2,LRRC8A,TMPO,SYNPO2,HIRA,VSNL1,XRCC4,ANKS1B,SMARCAD1,STOX2,FAM13C,HNRNPA3,GAN" MicroRNA hsa-miR-4288:mirSVR_highEffct hsa-miR-4288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.27E-45 4.07E-41 2.83E-44 2.60E-43 118 690 "RALGAPA1,XKR4,PTCHD1,BEND6,INTS2,SPOP,ANK2,PHF12,ATP2A2,DPY19L3,ADAM23,ADGRB3,RGS9,SGCE,NFS1,ZBED1,MAGI1,TIGD7,PPT2,SLC4A8,ABCG1,SNCAIP,SEC24C,SIPA1L1,VCAN,FAM169A,SLITRK5,RIMS2,DDX46,EXOG,E2F5,DCTN4,DENND4A,RASL12,FAM198B,TUBB3,CEP78,CHST15,GORAB,FER,SUCO,FOXF2,IQCG,FLT1,ANKFY1,ZNF605,ST6GALNAC3,NSG1,C15orf41,DISC1,GFRA2,PPARGC1A,ZNF638,GNAO1,FUT10,PSIP1,IDH3B,IGF1,SCIN,KCND2,MBNL1,LRP1B,MEF2C,MMP16,MYO7A,NTRK2,NUCB2,GNG2,PKD1,SNX10,JAKMIP1,PMP22,ING3,SEPT4,POLR2F,MAPK10,GRAMD1C,MASP1,SNRK,CNTLN,PTPN13,PTPRE,TTC13,FAM66C,RASGRF2,RDX,CARF,ABCA11P,CASC3,FAM81A,SLC6A8,BTBD7,CPEB4,DOP1A,PDZD2,TSNAXIP1,SP4,KDM4C,ZC3H13,LHPP,LMO3,PBLD,SEPT8,PHLDB1,C12orf76,DNMBP,ADGRL3,FBXW11,GPRIN3,FAM200B,AKTIP,UBE2H,OSBP2,ZNF45,LYPD6,EML6,FAM13C,TIGD6" MicroRNA hsa-miR-1296:mirSVR_lowEffct hsa-miR-1296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.97E-45 5.58E-41 3.87E-44 3.57E-43 125 774 "RALGAPA1,AS3MT,PTCHD1,HECW2,OSBPL1A,AMPD3,LCORL,PPP4R4,CDK13,ATP2A2,ADAM23,TTLL9,SGCE,DDR1,CAMK2G,VXN,METTL6,LRRFIP1,NUMBL,SRSF11,PLEKHB1,CNGA3,COL9A3,IGDCC3,RGS6,KIAA0040,KATNAL2,LONRF1,MAML1,SCRN1,GIT2,ELMSAN1,KIAA0753,DDX46,POM121,CHRDL1,DLX1,WDPCP,RASGRP1,ING4,CERCAM,VPS13B,COQ7,ERBB2,REEP2,CEP78,FER,GTF2IRD2,ATP5PD,SYT3,C2orf88,TMEM107,CELF1,SARAF,AP4B1,FYN,ZNF274,GATM,ADAM28,GLYR1,TOX3,ZNF638,LUZP2,LNX1,ADGRA3,CNTRL,HMGCR,GPR62,MAT2A,MBP,MEF2C,MPP2,ZNF862,P2RY13,OGG1,GPR173,PURG,PPM1B,WDR25,PTCH1,BDNF-AS,PTPRN2,ACSM5,MARCH1,TMEM255A,RASGRF1,RBBP6,HKR1,MSANTD2,DPF2,ALG9,SNX22,KIAA0895L,ZNF331,ATXN2,GALNT10,FBXO11,WDR37,SLC12A2,SLC14A1,NAPB,SMARCD3,MYO16,BDP1,SPTAN1,IQSEC2,RBM26,FAM208A,SYNE1,PHF24,PCDHB4,ENHO,ANKRD24,ZNF346,ELP5,SSBP2,UBE2H,OSBP2,XPO1,ZNF24,CELF4,POLR3H,LINC02210,ST8SIA2,JPH3" MicroRNA hsa-miR-363:PITA hsa-miR-363:PITA_TOP PITA 1.02E-44 5.72E-41 3.97E-44 3.65E-43 99 486 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-34b:PITA hsa-miR-34b:PITA_TOP PITA 1.05E-44 5.85E-41 4.06E-44 3.74E-43 88 379 "CLK4,CCDC85A,ADRB2,PCDH19,MARCH4,OGT,CALM1,PTBP2,CCK,ZMYM4,CFL2,FOXN3,CHN2,AHCTF1,MYRIP,PLCXD3,SPATA2,MBNL2,TENM1,EMX2,RCAN2,ERBB4,FGF14,FAM49B,GABRG2,CPLX1,ARFIP1,PCDH17,GHR,RAB40B,GPD2,TDRKH,PCLO,ZHX1,FRMD3,BACH2,MIER3,IGF1,IBA57,KIF2A,PIK3AP1,MAP2,MEST,MIA2,NEXMIF,MYT1,GPR137C,CNTN3,PDE4D,PDPK1,LRP12,SCHIP1,KANSL1,RELN,PTPRD,PTPRE,ZSCAN2,FIGN,AP1AR,SEMA6D,ATXN2,MRAS,SCAF8,CPEB3,CHD9,FNDC3A,SEPHS1,TET1,RCOR3,SNAP25,SNCA,SOX11,ZNF423,ARHGAP26,STAU1,ARHGEF9,ANKRD28,ADGRL3,TRIM2,PCDHB3,PUM2,AKTIP,CSMD1,TRPS1,FLRT2,LAMP5,KAT6A,TIGD6" MicroRNA hsa-miR-92b:PITA hsa-miR-92b:PITA_TOP PITA 1.24E-44 6.92E-41 4.79E-44 4.41E-43 99 487 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-92a:PITA hsa-miR-92a:PITA_TOP PITA 1.24E-44 6.92E-41 4.79E-44 4.41E-43 99 487 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-25:PITA hsa-miR-25:PITA_TOP PITA 1.24E-44 6.92E-41 4.79E-44 4.41E-43 99 487 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-367:PITA hsa-miR-367:PITA_TOP PITA 1.24E-44 6.92E-41 4.79E-44 4.41E-43 99 487 "FAM135A,PITPNM2,DPP10,SLC4A4,ATP2A2,HCN2,SYNJ1,CACNA1I,CAMK2A,DLGAP2,SOCS6,PCYT1B,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,DBT,PITPNC1,ZNF804A,CPEB2,ARRDC4,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,IQGAP2,GHR,PRRC2B,GPD2,MIER3,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,MYO5A,NEFM,NEFH,NF1,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,FNIP1,CPEB3,MYO18A,CPEB4,FAM126B,PDZD2,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,CSMD1,TSC1,SGK3,ZNF711,EVI5,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1" MicroRNA hsa-miR-19a-3p:Functional MTI Functional MTI miRTarbase 1.26E-44 7.05E-41 4.87E-44 4.49E-43 107 571 "MTUS1,HECW2,PCDH10,USP37,STX16,BCL7A,JAZF1,CALM1,PTBP2,EVI5L,CFL2,QKI,ARMC8,CLOCK,HDAC4,RASSF2,LONRF1,GIT2,DBN1,SPATA2,KLHL3,MTX3,WDR20,DPYSL2,HIPK3,TMTC1,MBNL2,PLXNC1,CERCAM,ERBB4,VPS26C,TLR7,KATNAL1,ACSL4,PRMT5,MED12L,RAPGEF6,AHDC1,MALT1,TNRC6A,PRUNE2,GRB10,CIT,ELOVL5,ZIC5,KIT,MBNL1,KITLG,AFF1,ZNF680,MYCN,IDNK,NF1,CNOT4,OCRL,PDE4A,CCSER2,PKM,PURG,SH3KBP1,PPARA,PPP2R5E,PRKACB,DEF8,PTPRB,PTPRG,RBBP8,KLHL11,CLIP1,SATB1,ATXN7,SGK1,FAM102A,CHD9,FNDC3A,EPN2,SLC6A8,NAPB,BTBD7,KIF13A,ZNF423,SPART,POGZ,MPRIP,RGL1,DIP2A,PRRC2C,ARC,ANKRD12,CAMTA1,EXOC7,ALG1,ATMIN,DMXL2,DICER1,ZMAT3,NACC2,CBX5,WBP2,ZNF138,ZNF154,ZFAND5,MFF,STOX2,WNK3,FXR1,FRMD6" MicroRNA hsa-miR-448:PITA hsa-miR-448:PITA_TOP PITA 1.51E-44 8.47E-41 5.85E-44 5.38E-43 94 438 "ADD1,UNC5A,HECW2,DOC2A,ARNTL,NCOA1,SYNJ1,PTBP2,CLDN10,SEPT7,SRSF11,SULT4A1,ARHGEF6,MYRIP,ZNF521,SOCS5,SLITRK5,PLCXD3,KIAA0408,DOCK4,DAPK1,RHOBTB1,CPEB2,MAMLD1,GOLT1B,KLHL5,FRY,MBNL2,EGR3,PAN3,GPHN,ETV1,FOXO3,AFF2,NBEA,GABRB3,MSTN,RAB40B,FERMT2,ZHX1,BACH2,SMAP1,KCNB1,PACRG,MEF2C,MEIS1,MITF,MYH3,NEXMIF,CNTN3,PCDH8,PCDH9,PDE4D,GPR85,SH3KBP1,PRKAB2,MTMR10,PTPRD,PTPRE,OXR1,ZFHX4,SETD5,ROBO2,RORB,HSPA4L,CHD9,NLGN1,ABLIM3,WDR47,SLC12A2,TMCC1,SOX11,CDK19,RBM26,SS18,SYN1,SYN2,ANKRD28,TACC1,FBXW11,TCF4,ZEB1,DOCK9,PUM2,CRTC1,TEK,SIRT1,TLR4,VLDLR,ZNF711,FZD3,FXR1,FRMD6,GAN" MicroRNA hsa-miR-1302:mirSVR_highEffct hsa-miR-1302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-44 8.50E-41 5.87E-44 5.40E-43 125 777 "RALGAPA1,KCNH8,FMNL2,GALNT13,BRAP,PWWP2A,UPRT,AQP6,ATP2B2,N4BP2L1,ADGRB2,NRP2,DST,ARHGEF7,SCAPER,CALB1,SYNGR3,CD38,LRRFIP1,CDO1,ABI3BP,ZFP28,GDA,CS,RUBCN,GPRASP1,RIPOR2,EARS2,ZBTB24,MYEF2,ALKBH8,RAB39B,DYNC1I1,SLC12A6,YAF2,APH1A,EPHB1,SRRM1,NCALD,F5,ARMCX1,TUBA1B,PTK2B,FCGR3A,FER,FGFR1,POLK,SUCO,SLC37A3,MEGF10,GABRG2,IQGAP2,DISC1,TNRC6A,ZNF638,KDM2B,LUZP2,PRUNE2,GRM8,MIER3,NKD1,KIAA1755,FAM69A,LRRTM1,STMN1,LIG4,HECTD2,MBD1,MBNL1,TM6SF1,KITLG,NEXMIF,NME4,VWA2,CNOT4,NOVA1,NTRK2,PCDH9,SNX10,PLCL1,SAMD9,VPS13C,OXR1,GSTCD,GLDN,ABCA11P,HUNK,NCBP3,SH3GL3,HKDC1,FBXO11,SYBU,SEC31A,ABLIM3,FAM81A,ATF7IP,ZNF667,INTS9,RCOR3,MAPKBP1,ANKFN1,CDK19,MPRIP,SULF2,SEPT3,PLCB1,SYT1,FAM208A,TCEA1,SYNE1,SLC19A3,OBSL1,DICER1-AS1,METTL3,TRPS1,RUSC1,TSC1,VSNL1,AGMO,TMEM237,MAP3K12,SIGLEC10,FAM47E,DOCK8,ST7" MicroRNA hsa-miR-520c-3p:PITA hsa-miR-520c-3p:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-302a:PITA hsa-miR-302a:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-520d-3p:PITA hsa-miR-520d-3p:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-302b:PITA hsa-miR-302b:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-302c:PITA hsa-miR-302c:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-373:PITA hsa-miR-373:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-520a-3p:PITA hsa-miR-520a-3p:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-302d:PITA hsa-miR-302d:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-302e:PITA hsa-miR-302e:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-520e:PITA hsa-miR-520e:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-372:PITA hsa-miR-372:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-520b:PITA hsa-miR-520b:PITA_TOP PITA 1.62E-44 9.05E-41 6.19E-44 5.70E-43 105 551 "PWWP2A,PTCHD1,MTUS1,AK2,SPOP,APBB2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,AKAP5,IGDCC3,ZNF385A,ARHGEF10,SOCS5,RUBCN,HDAC4,RASSF2,IP6K1,MFAP3L,ZC3H11A,DMTF1,E2F5,HIPK3,MBNL2,KMT5B,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PCDH17,MAP7D2,PCLO,MIER3,HLF,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NNAT,NRCAM,GPR137C,PCDH9,PLCL1,TRHDE,EPB41L4B,PPARA,KANSL1,MAPK9,SNRK,TMEM260,PTPRD,OXR1,RDX,GTDC1,SLC25A36,ALG9,SBF1,FNIP1,FBXO11,FNDC3A,WDR37,TET1,RCOR3,TMCC1,CDK19,LMO3,ERBIN,RGL1,STXBP1,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,UPF3A,EMSY,CADM2,PRDM8,PRDM10,PLSCR4,FAM13C,MARCH8,DPF3,ST8SIA2" MicroRNA hsa-miR-20b*:mirSVR_highEffct hsa-miR-20b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-44 9.68E-41 6.62E-44 6.09E-43 132 863 "PTCHD1,PCDH19,HACE1,OGT,CDC42BPA,APC,UPRT,APOC1,IGDCC4,ARNTL,ZBTB10,ATP2A2,ADGRB3,DST,ARHGEF7,MTMR2,CALB1,CALB2,CAST,LDB2,KRIT1,CHN2,CNOT8,FBXO7,HECTD1,SLC4A8,AHCTF1,CREM,AKAP12,RNF14,ERC2,USP6NL,KCTD8,DMTF1,ARRDC4,SEZ6L2,TSPAN5,PHC2,FSD1L,YAF2,FAM13A,PHF20L1,SUGP2,KMT5B,RGS17,C8orf37,CALCRL,CEP85L,ETV1,F8,ZNF461,TMEM132C,CEP78,GABRA3,C15orf41,SULT1C4,PCDH17,ZNF638,GPD2,PCLO,DIDO1,GSTM5,MAP4K5,HMGCR,TCEAL6,ZNF181,ZNF678,KCNN2,CREG2,LMO2,PIK3AP1,MAP2,MAP4,LRP1B,MIA2,ADAM22,ZNF92,TCEAL5,VWA2,SLC11A2,PCSK5,PDE4B,PDE4D,GNG2,CYTL1,NALCN,XRN1,FAM216A,MINDY2,PPM1B,LRRN3,PPP3CA,RANBP3L,EPDR1,MAPK10,CNTLN,PTK2,EML5,ZNF615,ZNF493,GAL3ST4,RNASE1,ABCA11P,RCOR3,SNCA,MBD5,SNRPN,SEPT8,ADHFE1,NUDT10,COBL,TCF4,ZFP90,ITGB3BP,ACTR6,TMPO,PPIL6,SGK3,CLDND1,ZNF711,FSTL5,FAM47E,FAM13C,AMN1,HNRNPA3,FBXO36,CASC15,ACTR3B,ADAMTSL3,NHSL1,FRMD6,NETO1" MicroRNA hsa-miR-31-5p:TargetScan hsa-miR-31-5p TargetScan 1.86E-44 1.04E-40 7.09E-44 6.53E-43 83 336 "NDRG3,ADCY6,KIAA1211,AK2,PDZD4,PHF12,APBB2,EPB41L5,ARRB1,NUMB,DPY19L3,FUBP1,JAZF1,CAMK2G,CCNT1,DGKI,ARHGEF2,CLCN3,QKI,CLOCK,PREPL,PLXNA4,CTH,RHOBTB1,DMD,EDNRB,CNNM1,HEYL,EIF5,PLEKHA1,EIF1,COQ7,RAB9B,CEP85L,ANKFY1,KHDRBS3,GABBR1,GABRA3,GRB10,MAP4K5,BACH2,KCNN3,LSAMP,AFF1,MMP16,MYO5A,OPRL1,PCDH8,PDE4D,PDPK1,PIK3C2A,PPP3CA,FITM2,EML5,PTPRG,RDX,GTDC1,FIGN,RGS4,GSTCD,CSRNP3,ATF7IP,EPC1,PDZD2,IQSEC2,CLASP2,CLSTN2,KANK1,RHBDL3,MMS19,SATB2,GPRIN3,DICER1,CBX5,CSMD1,IL34,NR2C2,OSBP2,POLR3H,DPYSL5,CIAPIN1,FZD3,FXR1" MicroRNA hsa-miR-3198:mirSVR_highEffct hsa-miR-3198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-44 1.11E-40 7.59E-44 6.99E-43 114 651 "KCNH8,NCKAP5,SYS1,PLEKHH1,CC2D2A,AMT,MYH7B,PKP4,APC,MARK4,ADAM23,CFLAR,BMP7,THSD7A,KALRN,KRIT1,ARHGEF2,DIS3L,CHN2,LHX2,CPNE6,RAB33A,FBXO7,CNR1,MYRIP,IGDCC3,SLC35F1,SNCAIP,RGS6,VCAN,UBXN2A,KATNAL2,ARHGAP24,SCRN1,ARMCX4,DDX46,SLC25A18,DTNA,EBF1,EDN3,FRY,TMEM35A,SRRM1,DENND4A,IGSF6,FAM198B,GORAB,FGF12,POMT1,OGA,ZNF44,ERAP1,KIAA1841,TCERG1,RAB30,GPD2,TDRKH,GRIA2,GRIN2D,RABL2A,IRAK3,RASSF8,SMAP1,NME9,LAMA2,MAP2,LAYN,MYO7A,NPTX2,PCSK5,ENPP2,FAM216A,PMP22,STRN3,EPB41L4B,PKIA,TMEM260,ACSM5,ACSS3,ZNF793,SUSD4,FIGN,NUDT11,GLDN,ATAT1,SHC4,FNDC3A,CNKSR2,ATF7IP,SNAP25,MBD5,SNRPN,PEG10,MCF2L2,PBLD,SEPT8,CAMTA1,DOCK9,HIF3A,FAM200B,AP4E1,HEY1,TMPO,SYNPO2,KCNE5,MTCH1,CCDC14,P2RY12,GUSBP1,ZIC1,LYPD6,CELF4,FBXO36,CASC15" MicroRNA hsa-miR-432:mirSVR_highEffct hsa-miR-432:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-44 1.15E-40 7.86E-44 7.24E-43 131 852 "ABHD6,GALNT13,PWWP2A,APAF1,APOC1,INSYN2B,EIF4G3,SLC2A11,N4BP2L1,DPY19L3,ADGRB3,DST,SYNJ2,MTMR2,THSD7A,KALRN,PTBP2,PRC1,CCNH,USP2,DGKI,ARHGEF2,RAB28,NRXN3,PPT2,AKAP6,COL4A5,SLC35F1,RNF14,SOCS5,PDE4DIP,ARHGEF4,USP6NL,DOCK4,EARS2,PITPNC1,ELMSAN1,HEPH,RHOBTB1,GRIN3A,HS3ST2,DYNC1I1,CPEB2,DTNA,DNAJB6,DNM1L,OPTN,PHF20L1,GOLGA7,PLEKHA1,EMX2,TLR7,FCGR1A,FCGR3A,KAT8,POLK,SEMA4D,NOP56,C2orf88,ZMAT1,MEGF11,GABBR1,GAD1,GHR,PPARGC1A,TCERG1,LOXL3,PCLO,GRIA2,ZNF496,AGBL5,IL6ST,SLC35G1,TTYH2,MAP2,ADAM22,ZNF92,NRCAM,PCSK1,PDE1B,GNG2,ZNF655,PILRA,PPARA,MINDY2,MASP1,SAMD9,BDNF-AS,TMEM260,RAD51D,RASGRF1,RFX3,RNASEL,ARMC5,PGBD4,FBXW7,ADAL,ATAT1,ZNF331,ABLIM3,DHX30,WDR47,CCDC88A,IFT122,ANKRD36,SNRPN,MCF2L2,RBM26,POGZ,SST,ADHFE1,NUDT10,SYN1,ADGRL3,DMXL2,PUM2,ICAM5,ERCC6L2,TMPO,UBE3A,OSBP2,VGF,ZNF23,ANKS1B,FTSJ1,MEIS3,RGS7BP,DOCK8,CASC15,FAM219B,KLHDC1" MicroRNA hsa-miR-636:mirSVR_highEffct hsa-miR-636:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-44 1.22E-40 8.30E-44 7.64E-43 111 618 "SYS1,ACTN1,ADD2,BRAP,AGT,RTL9,NME5,OSBPL8,SEMA6A,MARCH4,AMPD3,NUMB,N4BP2L1,DPY19L3,TTLL9,ADGRB3,LINC00847,DST,NAE1,ZNF501,KRIT1,CRHBP,HAPLN1,SOCS5,VAC14-AS1,PUM1,DCAF4,USP6NL,GAPVD1,ARHGAP24,SV2B,DLX1,HS3ST2,NR1D2,DNAJB6,KLHL5,SUGP2,EGFR,MBNL2,IRAK4,EMX2,NRN1,FAM198B,FCGR3A,KAT8,GTF2IRD2,FGF12,SEMA4D,NELFCD,WDR83,CGREF1,OGA,IP6K3,SIGLEC8,MTHFD2,GGTA1P,TXNL4A,FERMT2,GPD2,GPR34,RNF165,FAM222A,ATXN2L,RBPJ,HECTD2,PPM1L,PCBP3,TBC1D25,OCRL,PCDH9,ZDHHC8,DUSP26,LRP12,PRKACB,MASP1,RELN,QRICH1,TMEM260,STK32A,ZSCAN32,DHX30,DIP2A,NECAB1,SYNE2,C12orf76,TCF4,SATB2,ZFP90,SZT2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,C18orf54,TNS1,SMUG1,TRO,TTC3,RPL7L1,RICTOR,TRIM9,PRTFDC1,ITM2C,SMIM8,MSRB3" MicroRNA hsa-miR-641:PITA hsa-miR-641:PITA_TOP PITA 2.19E-44 1.23E-40 8.37E-44 7.70E-43 99 490 "ACTN1,FMNL2,USP31,ALCAM,OGT,PKP4,TMEFF1,BACH1,THSD7A,PTBP2,B4GALT6,MAP4K4,NCOR1,OSBPL3,CSNK1G3,CNTNAP2,USP6NL,SPOCK2,ZNF804A,ZC3H11A,MTX3,DUSP9,EIF4G2,TENM1,EMX2,EPHB1,DNAJC27,FGF13,HPCAL4,FOXO3,PCDH17,MAP7D2,SERP2,MAP4K5,ZHX1,HLF,ELOVL5,ZIC5,KIF5A,KIT,PIK3AP1,MAT2A,ADAM11,CHIC1,BLOC1S2,MXI1,NEFM,NEFH,NF1,NFIX,NRCAM,PCDH9,PDE4B,PIK3C2A,PIK3R1,CCSER2,PLCL1,TRHDE,MAPKAP1,STRN3,LRP12,MINDY2,PPP2R5E,KANSL1,MAPK10,RELN,PTK2,PTPRG,RIPOR1,ZFHX4,CARF,CLIP1,FNIP1,CHD9,CXXC4,RCOR3,SOX11,HECW1,PEG10,POGZ,ERBIN,RGL1,ANKRD28,CAMTA1,SLC35G2,TEK,AP4E1,KAT6B,NR2C2,TRPS1,UBE3A,CLDND1,ZNF32,SMARCAD1,RGS7BP,KAT6A,HNRNPA3,MSRB3,FRMD6" MicroRNA "TGGTGCT,MIR-29C:MSigDB" "TGGTGCT,MIR-29C:MSigDB" MSigDB 2.28E-44 1.27E-40 8.67E-44 7.98E-43 98 480 "ASIC1,XKR4,PITPNM2,PARG,USP37,N4BP2L1,BCL7A,CAMK2G,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,NCOR2,FAM131B,HDAC4,DBT,ELMSAN1,ARRDC4,FEM1B,KMT5B,PLEKHA1,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,PPARGC1A,RAB30,FERMT2,GPR37,ADAMTS13,RNF165,ADAMTS6,BACH2,HMGCR,HNF4G,IGF1,TTYH2,MAP6,MAT2A,MYCN,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,DEF8,EML5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,SMPD3,SGK1,PPM1E,CPEB3,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,TPM1,ZNF346,TUBB2A,NDRG4,SLC30A3,EMSY,ADAMTS9,NAV3" MicroRNA "TGGTGCT,MIR-29B:MSigDB" "TGGTGCT,MIR-29B:MSigDB" MSigDB 2.28E-44 1.27E-40 8.67E-44 7.98E-43 98 480 "ASIC1,XKR4,PITPNM2,PARG,USP37,N4BP2L1,BCL7A,CAMK2G,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,NCOR2,FAM131B,HDAC4,DBT,ELMSAN1,ARRDC4,FEM1B,KMT5B,PLEKHA1,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,PPARGC1A,RAB30,FERMT2,GPR37,ADAMTS13,RNF165,ADAMTS6,BACH2,HMGCR,HNF4G,IGF1,TTYH2,MAP6,MAT2A,MYCN,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,DEF8,EML5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,SMPD3,SGK1,PPM1E,CPEB3,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,TPM1,ZNF346,TUBB2A,NDRG4,SLC30A3,EMSY,ADAMTS9,NAV3" MicroRNA "TGGTGCT,MIR-29A:MSigDB" "TGGTGCT,MIR-29A:MSigDB" MSigDB 2.28E-44 1.27E-40 8.67E-44 7.98E-43 98 480 "ASIC1,XKR4,PITPNM2,PARG,USP37,N4BP2L1,BCL7A,CAMK2G,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,NCOR2,FAM131B,HDAC4,DBT,ELMSAN1,ARRDC4,FEM1B,KMT5B,PLEKHA1,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,PPARGC1A,RAB30,FERMT2,GPR37,ADAMTS13,RNF165,ADAMTS6,BACH2,HMGCR,HNF4G,IGF1,TTYH2,MAP6,MAT2A,MYCN,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,DEF8,EML5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,SMPD3,SGK1,PPM1E,CPEB3,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,TPM1,ZNF346,TUBB2A,NDRG4,SLC30A3,EMSY,ADAMTS9,NAV3" MicroRNA hsa-miR-549:mirSVR_highEffct hsa-miR-549:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.68E-44 1.50E-40 1.02E-43 9.38E-43 131 854 "KCNH8,CLK4,NDRG2,TMEM132B,BEND6,KCTD16,AK2,PCDH10,AMPH,OGT,APAF1,BCAS1,ZBTB10,DPY19L3,BACH1,KRIT1,LRBA,SOCS6,ARMC8,AKAP6,SMARCAL1,CLOCK,NCOR1,GDA,DZIP3,ERC2,PUM1,RUBCN,CCDC144A,CYBB,DAPK1,GIT2,DDX46,ALKBH8,CHRDL1,EXOG,DMTF1,PDCD6IP,SEMA3D,MBNL2,GOLGA7,TENM1,RASL12,FHL1,FLT1,AP4B1,SDCBP2,ZMAT1,ZNF44,ERAP1,C15orf41,BRD8,LUZP2,GPT2,LNX1,ADGRA3,PRUNE2,SOX21,RASSF8,MIER3,EID2B,ZNF546,KCND2,CREG2,MAP6,MARK1,AFDN,CNOT4,NUCB2,PAX6,PCDH9,SLC10A4,PFKFB2,ING3,EPB41L4B,PPM1B,PRKCB,SNRK,CNTLN,PTPRD,ZNF493,ERI2,GSTCD,ELP2,GLDN,FNIP1,SCAF8,SGK1,FERMT1,CPEB3,CHD9,FBXO11,ZKSCAN3,ZFP1,ZNF667,LIMCH1,KIF13A,DOP1A,SP4,PEG10,SAMSN1,NEK4,TTBK2,KLHL7,VPS13A,SYN2,TAF9,ADGRL3,THRA,ERCC6L2,TMPO,NPL,NUTM2A,CLHC1,UBE3A,GUSBP1,TRIM9,AGMO,FSTL5,ZNF189,LAMP5,SMARCAD1,EMSY,PRDM10,MDH1B,WNK3,RGS7BP,FAM13C,UBE3B,HNRNPA3,CASC15" MicroRNA hsa-miR-4255:mirSVR_highEffct hsa-miR-4255:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-44 1.56E-40 1.06E-43 9.75E-43 130 842 "PWWP2A,PTCHD1,ADRB2,TAOK1,C1QTNF3,SEMA6A,AMPH,LRCH2,MAP4K3,APC,PPP4R4,RASL11B,ARHGEF7,JAZF1,SLC25A14,SPAG9,CLDN10,ARHGEF2,CHN2,HECTD1,FAM149A,BAG4,IGDCC3,FAM171B,C2CD2,GDA,SIPA1L1,HDAC9,GPRASP1,HEPH,ALKBH8,SACS,USP3,CPEB2,DPH1,WDPCP,ANKRD46,MBNL2,KMT5B,EIF5,PLEKHA1,EPB41L2,SH3YL1,FCGR1A,FDFT1,POLR1B,SUCO,MEX3B,FLT1,ANKFY1,SLC37A3,HVCN1,ATP6V1H,HHIPL1,OGA,FYB1,GALC,GCNT2,CRCP,TCERG1,DBF4,TOX3,CBX1,GSTT2,PSIP1,ZHX1,GABARAPL2,HNMT,ZIC5,RBPJ,ITPKB,KCNN2,SYTL4,MARK3,MBNL1,LRP1B,NF1,OXTR,PCSK1,PDE4B,RETREG1,PCDH18,PIGG,PTX3,CEP97,ACSS3,OXR1,GTDC1,RGS12,RIC8B,CYB561D1,ELP2,NCBP3,SCP2,R3HDM2,CNKSR2,CCDC88A,SLC12A2,LIMCH1,PDZD2,BDP1,SP2,ZC3H13,CLSTN2,LARP4,ADHFE1,CAMTA1,FBXW11,TCEA1,TRIM2,AKTIP,ERCC6L2,BEX4,TPM1,STXBP4,HIRA,UBE3A,UGT8,KLC2,XPO1,SLC47A2,ZBTB14,CELF4,WNK3,UBE3B,HNRNPA3,ACTR3B,KLHDC1,FRMD6,IFT88" MicroRNA hsa-miR-452:PITA hsa-miR-452:PITA_TOP PITA 2.86E-44 1.60E-40 1.09E-43 9.99E-43 95 451 "FAM135A,ZNF687,SYNJ1,FUBP1,JAZF1,CAMK2G,CLDN10,CDH2,CACNA2D2,FOXN3,CHN1,QKI,ARHGEF6,CLIP3,SIPA1L1,ERC2,DOCK4,HDAC4,MATR3,GRIN3A,CPEB2,DPYSL2,PDCD6IP,DUSP9,RASGRP1,KMT5B,PLEKHA1,PAN3,DCTN4,ERBB4,HPCAL4,PCDH17,TOX3,TDRKH,ADAMTS6,FRMD3,MIER3,ELOVL5,AGFG1,IGF1,KIT,LIFR,NCOA7,MEF2C,MEIS1,AFF1,CNTN3,PCSK1,PDE4D,SERPINI1,STRN3,RELN,SNRK,TMEM255A,REV3L,PBRM1,ZNF532,ROBO2,KCNIP1,SEMA6D,TRA2B,FBXO11,FNDC3A,BTBD7,CPEB4,SMARCA4,SNAP25,MBD5,TMCC1,PDZRN3,SOX11,SP4,NKAIN2,SS18,ERBIN,PLCB1,SYPL1,SYT1,MTCL1,MGRN1,TCF4,CUX2,DOCK9,RIMBP2,TP53BP2,UBE3A,FLRT2,LYPD6,ZBTB38,CADM2,NAV3,HNRNPA3,ACTR3B,MSRB3,ST8SIA2" MicroRNA hsa-miR-93-5p:Functional MTI Functional MTI miRTarbase 2.92E-44 1.64E-40 1.11E-43 1.02E-42 159 1220 "FMNL2,ADD1,FZD9,AP2A2,SORCS2,ZNF578,SEMA7A,APBB2,ATP1B3,STX16,LDHD,ARHGEF7,MTMR3,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,SOCS5,DZIP3,UBXN2A,PPP6R2,ARHGAP32,DCAF8,DAPK3,IP6K1,DNAL1,SPATA2,YTHDC1,ELMSAN1,DCTN1,FBXL5,DDX46,SACS,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,KMT5B,EIF4G2,IRAK4,PLEKHA1,CERCAM,DCTN4,MTSS1L,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,MED12L,GTF2IRD2,POLR1B,SUCO,FOXO3,ANKFY1,USP21,TPK1,MSANTD4,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,PRUNE2,FUT10,CIT,FICD,HAS2,ZIC5,IBA57,ITPKB,KCNB1,IPO5,CAMK2N2,SFXN5,GPR155,CHIC1,SCAMP5,AFF1,MXI1,HNRNPM,NBL1,CNOT4,OCRL,GPR137C,PDPK1,PFKFB2,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,CEP97,OXR1,REV3L,PBRM1,ZNF532,ATAT1,AP1AR,TMEM200C,HSPA4L,FAM102A,CHD9,SYBU,WDR37,BTBD7,CMTR2,FAM126B,SP2,SP4,STAC2,ANKRD12,CAMTA1,TAF6,SMG6,TCF4,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,PARD3,RGMB,NR2C2,TSN,UBC,VLDLR,ZIC2,ZNF70,EMSY,CADM2,MPPE1,WNK3,UBE3B,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-3152:mirSVR_highEffct hsa-miR-3152:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-44 1.97E-40 1.33E-43 1.23E-42 115 666 "ASPHD1,XKR4,LRFN2,BEND6,SPARCL1,DPP10,ANK2,ARNTL,STX16,ATP2A2,ZNF582,LINC00847,CALM1,CAST,MTMR7,SEPT7,SOCS6,MAP4K4,FHL5,ARMC8,AKAP6,AHCTF1,ANKRD44,TRIM69,ARHGEF10,PHACTR3,PNPLA8,HDAC9,DYNC1I1,CPEB2,ACOT8,DTNA,ECM2,DNAJB6,E2F5,CNNM1,FSD1L,YAF2,GOLGA7,EIF4G2,EMX2,IGSF6,FAM198B,RPS6KC1,GORAB,GTF2IRD2,FHL1,SUCO,SLC37A3,STAMBP,STAU2,FYB1,GALC,SIGLEC8,ARFIP1,CYP46A1,KIAA1958,WDFY3-AS2,FUT10,RNFT2,ADAMTS6,HSF2,RBPJ,KCNN2,SFXN5,MAP2,MARK1,MBNL1,NF1,CLDN11,CYTL1,CCSER2,PPP2R5E,SAMD9,MTMR10,PTPRD,PTPRE,ZNF615,RDX,SETD5,RPE,NEK11,LRRK2,ABCA11P,ATAT1,SCN8A,TNFRSF19,CPEB3,SNAP25,KIF13A,TRERF1,PBLD,NKAIN2,NXT2,DIP2A,SYT1,C12orf76,CAMTA1,ALG1,SIN3B,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,C18orf54,FAM155A,MTCH1,PRDM10,ADAMTSL3,TIGD6,SNX14" MicroRNA hsa-miR-522:PITA hsa-miR-522:PITA_TOP PITA 3.65E-44 2.04E-40 1.39E-43 1.28E-42 100 503 "CLK4,USP31,BEND6,MTA3,CASKIN1,OSBPL6,TAOK1,LRCH2,EVI5L,NUMBL,CACNA2D2,FOXN3,SOCS6,CNTFR,AKAP6,HDAC4,DGKB,ARMCX2,MYEF2,ZC3H11A,SNAP91,NR1D2,SLC12A6,DNAJB6,EDNRA,APH1A,EGR3,PLEKHA1,EIF1,ETV1,EZH1,ACSL4,DLC1,OLFM1,PRKAG2,SUCO,SYNCRIP,NBEA,CSPG5,OGA,PCDH17,PPARGC1A,TNRC6A,KDM2B,GNAO1,ZHX1,BACH2,MIER3,IDH3A,KIT,STMN1,MBNL1,LRP1B,MEF2C,KITLG,MYO5A,HNRNPM,NFE2L2,TBC1D25,PPP2R5E,SNRK,RDX,KIF7,ZNF532,ALG9,CCDC25,SALL1,FNIP1,GALNT10,SGK1,KIF21A,PPM1E,CPEB3,SHC4,WDR37,SLC12A2,RCOR3,SNAP25,SNCA,NMNAT2,HECW1,MYCBP2,LMO3,TCF4,RPGRIP1L,SZT2,NSD1,SIRT1,KAT6B,FAM155A,UBE3A,CLDND1,PCDH20,ZIC1,KCNT2,LYPD6,MAP3K12,HNRNPA3,FRMD6,NETO2" MicroRNA hsa-miR-152:PITA hsa-miR-152:PITA_TOP PITA 4.05E-44 2.27E-40 1.53E-43 1.41E-42 98 483 "ASIC1,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,MARCH3,NCOA1,ADGRB3,BCL7A,SYNJ1,CALM1,CAMK2A,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,RUBCN,SNPH,SNAP91,RAB39B,DMPK,KLHL5,FRY,EGR3,SLC43A2,EZH1,SCML2,MED12L,PRKAG2,C15orf41,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,KIT,STXBP5,MITF,NDP,NFIX,NPTX1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,PIK3C2A,ANKRD16,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,SCN2B,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,PLCB1,SYT1,TCF4,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TRPS1,TMEM237,SLC38A1,RTN4,KAT6A,FXR1,JPH3" MicroRNA hsa-miR-148b:PITA hsa-miR-148b:PITA_TOP PITA 4.05E-44 2.27E-40 1.53E-43 1.41E-42 98 483 "ASIC1,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,MARCH3,NCOA1,ADGRB3,BCL7A,SYNJ1,CALM1,CAMK2A,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,RUBCN,SNPH,SNAP91,RAB39B,DMPK,KLHL5,FRY,EGR3,SLC43A2,EZH1,SCML2,MED12L,PRKAG2,C15orf41,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,KIT,STXBP5,MITF,NDP,NFIX,NPTX1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,PIK3C2A,ANKRD16,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,SCN2B,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,PLCB1,SYT1,TCF4,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TRPS1,TMEM237,SLC38A1,RTN4,KAT6A,FXR1,JPH3" MicroRNA hsa-miR-15a*:mirSVR_highEffct hsa-miR-15a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-44 2.32E-40 1.57E-43 1.45E-42 111 622 "NCKAP5,KLHL32,ESYT2,RTL9,ANK2,LCORL,TMEM108,BCHE,BID,DST,MTMR2,C5,DDR1,KALRN,PTBP2,SLC25A14,SEPT7,SOCS6,NDST3,PLAA,TPP1,SLC4A8,ZFP28,CNRIP1,ANKRD44,SNCAIP,SIPA1L1,KATNAL2,IP6K1,ARMCX2,ELMO1,RHOBTB1,CPEB2,DPYSL2,DTNA,DTNB,WDPCP,TNK2,STARD3NL,ENO2,LRRC17,GMPR2,FGF14,POLK,MEX3B,ZBED3,ATP6V1H,FYN,GALNT15,DISC1,SULT1C4,MSTN,ARFIP1,TOX3,STMN2,FAM19A2,ATOH8,ARHGAP36,HNMT,MAN2A2,AQP11,TM6SF1,MMP16,NRBP2,NOVA1,PLCL1,STRN3,PKIA,MAPK9,GRAMD1C,PPP2R3C,TRIM68,RGS4,PBRM1,RNASEL,EXD2,PNMA8A,PTGR2,DGLUCY,SATB1,ATXN2,LRFN5,SH3GL3,CHD9,CNKSR2,NLGN1,ABLIM3,ARHGEF40,ATF7IP,SNRPN,TROVE2,LARP4,ADHFE1,FAM208A,DOCK9,PCDHB4,PUM2,CRTC1,FRYL,METTL3,CCDC14,RICTOR,ZNF711,ZNF45,LYPD6,CADM2,MDH1B,URM1,UBE3B,KAT6A,SMIM8" MicroRNA hsa-miR-2277:mirSVR_lowEffct hsa-miR-2277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.55E-44 3.11E-40 2.10E-43 1.93E-42 112 635 "ACHE,OSBPL1A,GPRASP2,PHF12,PPFIA3,CDK10,SPTBN4,ARHGDIA,MARK4,N4BP2L1,ADAM15,BACH1,CACNA1G,CAMK2B,CAPN3,PRC1,DIS3L,RAB28,HECTD1,MAGED1,ABI3BP,CREM,HDAC9,GAPVD1,KCTD8,SV2B,SPOCK3,DLX1,DNM1,USP3,DPH1,DTNA,FIS1,AASDH,FRY,EIF4G2,TNK2,ELN,TMEM35A,GPHN,BAIAP2,IP6K2,EVL,POMT1,TMEM107,SESN1,TCERG1,TNRC6A,GRIA2,RNFT2,ELOVL5,AGBL5,HSF2,CELF5,IDH3B,IL6ST,GATD1,PAXBP1,LRP1B,NNAT,DNHD1,PKD1,POLR2F,PPP1R1A,PRPH,PTPRO,ZMAT4,RET,REV3L,FIGN,ZFHX4,RORB,DGLUCY,PPM1E,FAM81A,SLC22A4,MBD5,USP33,KLHL7,PRRC2C,PLCB1,ASTN2,C12orf76,CAMTA1,MLST8,ZEB1,SYNE1,NAT16,DOCK9,PCDHB7,PUM2,TNS2,PCDHA5,RIMBP2,TP53BP2,TRO,DCBLD1,CLEC2L,UGT8,CLDND1,GUSBP1,XRCC4,ZNF711,TRIM9,PRDM10,NELFE,UBE3B,SMIM8,CASC15,ADAMTSL3,RSPRY1,ZDHHC20" MicroRNA hsa-miR-421:TargetScan hsa-miR-421 TargetScan 6.21E-44 3.48E-40 2.35E-43 2.16E-42 82 332 "C3orf14,APBB2,GAS7,AQP6,RIPK1,FUBP1,LDLRAD4,RUNX1T1,C1orf52,CFL2,CLCN3,QKI,ARMC8,MAGED1,NRG2,CS,APPL1,PLCXD3,CTH,DGKB,JAKMIP2,KIAA0753,EGFR,PLXNC1,ENPP6,PIPOX,DNAJC27,FGF13,FGF14,FAM49B,CPLX1,GCNT2,GHR,PRUNE2,GRM8,KAT7,BACH2,AGFG1,IL6ST,IPO5,MEF2C,MEIS1,MEIS2,MITF,MXI1,NFYA,CNOT4,OPA1,CLDN11,PDE4B,PDPK1,PFKFB2,NLE1,PLCL1,EPB41L4B,PPP2R2C,KANSL1,PTPRB,RDX,GTDC1,RORB,KIAA0895L,MCMBP,ARX,BTBD3,CPEB4,FAM126B,ARHGAP26,MPRIP,ARHGEF9,GPRIN3,ERCC6L2,CDK20,NR2C2,FLRT2,CLIP2,POLR3H,ANKS1B,MAP3K12,KAT6A,GAN,CPNE4" MicroRNA hsa-miR-3118:mirSVR_highEffct hsa-miR-3118:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-44 3.70E-40 2.50E-43 2.30E-42 128 824 "KCNH8,INTS2,KIAA1324,WDR35,AMPH,SUGT1P4-STRA6LP-CCDC180,EPB41L5,ZBTB10,NCOA1,NUMB,ATP2A2,ATP6V0A1,BACH1,MPDZ,MTMR2,CARS,RUNX1T1,ZNF501,SLC16A4,P2RX6,MAGI1,CHN2,TPP1,FAM19A5,MAP4K4,ARHGEF6,CPS1,FAM171B,ANKRD44,SNCAIP,ARHGEF10,KIAA0040,RIMS2,ZSCAN23,DOCK4,ARMCX2,DMD,DNAH9,PDCD6IP,EDN1,EDNRA,EGFR,KMT5B,GOLGA7,EIF1,VPS13B,EXTL2,TAOK3,ZNF605,GABBR1,ERAP1,MSTN,PPARGC1A,GLUL,CBX1,GNAL,GNAO1,MCHR1,PSIP1,HAS2,ARHGAP36,MIER3,HNMT,KPNA5,STMN1,NCOA7,MAT2A,MBNL1,LRP1B,MMP16,NFE2L2,NRCAM,NTRK2,LOC100128398,GPR137C,PCDH9,NALCN,PIK3C2A,XRN1,PLCB2,CEP41,HYDIN,BCAS3,PTPRB,SUSD4,CRTAC1,NUDT11,ROBO2,ELP2,PCMTD2,RPL15,ATP8B4,ADAL,ZNF354C,TNFRSF19,CCDC92,SLA,SLC14A1,GKAP1,ZNF415,SNRPN,SP4,SPTAN1,NFASC,CLSTN2,KANK1,VPS13A,FBXW11,ZFPM2,TMEM9,KAT6B,PPIL6,SSBP2,ZKSCAN5,SGK3,WIPF1,ZNF711,ZNF28,TRIM9,NDRG4,MKRN3,FSTL5,SLC30A4,MFF,ADAMTS9,TRAM2-AS1,KLHDC1,SENP7" MicroRNA hsa-miR-619:mirSVR_highEffct hsa-miR-619:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.92E-44 4.43E-40 2.99E-43 2.75E-42 126 801 "SYN3,NDRG3,NDRG2,KLHL32,ADCY6,DPY19L2P4,ZNF608,HECW2,KCTD16,WDR35,ALCAM,OGT,MAP4K3,APC,MAGEE2,CDC14B,ARNTL,MARCH3,EIF4G3,ZNF583,ATP6V1G2,BBS2,PROM1,ST3GAL5,RUNX1T1,KYAT1,CERS5,LRBA,MAGI1,PLEKHB1,B4GALT6,TMEM184B,CNR1,FAM149A,AHCTF1,IGDCC3,FAM171B,ANKRD44,CLIP3,SNCAIP,CCDC144A,GIT2,ARMCX4,FBXL5,ZC3H11A,ALKBH8,CPEB2,PHF20L1,EGFR,KMT5B,EGR3,CERCAM,MRNIP,TMEM35A,VPS13B,ZNF461,ZSCAN30,EVL,STAU2,SARAF,GABRG2,KIAA1841,TUBGCP4,ZNF276,CRCP,GLI2,GPD2,STON1,LPAR4,PRDM5,FAM19A2,RNFT2,TOX2,RBPJ,IL6R,IL6ST,NCOA7,MSI1,ADAM22,NCF2,NF1,DNHD1,GLIPR1L2,PCDH9,PCSK5,CYTL1,CCSER2,RANBP3L,PRKACB,MAPK9,GRAMD1C,MASP1,ZSCAN32,PTPRB,PTPRD,ZNF615,TRIM68,SLC25A36,CCDC82,ADAL,PEX26,KDM4D,BDP1,KDM4C,LMO3,ATP10B,ERBIN,ZSCAN29,NEK4,SULF2,NUDT10,FRYL,ITGB3BP,SYNPO2,RUSC1,FAM155A,ZNF709,BCL2L13,ZNF154,LAMP5,PRTFDC1,PRDM10,RNF103,VPS35L,PARP11,CASC15" MicroRNA hsa-miR-202:mirSVR_highEffct hsa-miR-202:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.19E-44 4.58E-40 3.09E-43 2.84E-42 116 683 "XKR4,ADD2,KIAA1211,PTCHD1,INTS2,MAP4K3,TNRC6C,PPP4R4,ZBTB10,ADAM23,BCL7A,SYNJ1,SYNJ2,CASTOR3,L3MBTL4,MS4A7,NDST3,TPP1,ARMC8,ABI3BP,RCHY1,CREM,SEC24C,VCAN,CNTNAP2,ZFYVE16,ZC3H11A,CPEB2,DRP2,WDPCP,SEMA3D,YAF2,FAM13A,TMEM35A,STARD3NL,RABEPK,GMPR2,DLC1,FHL1,IP6K2,NELFCD,AKAP3,ATP6V1H,ATP2C1,SARAF,GABRG2,GAD1,SULT1C4,GHR,PPARGC1A,RAB40B,GRIA2,PLCD4,PSIP1,HAS2,ZDHHC15,SMAP1,IRF8,MYLK2,IL12A,SLC35G1,KCNK3,KIF2A,IPO5,LAMP2,LIMS1,HECTD2,MEIS1,MEIS2,MYCN,CNOT4,PCBP3,GPR137C,GNG2,XRN1,PURG,TRHDE,EPB41L4B,LRRN3,GDPD1,LAMA1,TMEM260,PTPRD,PTPRG,PTPRO,PPP2R3C,RASGRF1,RASGRF2,SLC25A36,CARF,ATXN2,CPEB3,DZIP1,SLC12A2,CPEB4,SPATA7,HECW1,ST5,SULF2,PRRC2C,SYN2,SYT1,SYNE1,DICER1,ERCC6L2,ZNF709,MICU3,ZNF540,SPIRE1,SMARCAD1,ZNF225,SLC30A4,ADAMTS9,HPS4,PHTF2,CASC15" MicroRNA hsa-miR-544b:mirSVR_highEffct hsa-miR-544b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.80E-44 4.92E-40 3.32E-43 3.05E-42 104 550 "KCNH8,EMILIN3,NDRG2,KLHL32,CC2D2A,AK2,UPRT,ZFYVE28,ARRB1,CDK13,RGS9,SGCE,MYRF,CALM1,SLC25A14,CAST,CBR1,CLDN10,TIGD7,NDST3,LY86,IQCK,ABI3BP,CREM,HINFP,SNCAIP,SEC24C,IST1,HEPH,EXOG,DMTF1,DPP6,ARRDC4,DTNA,ABCC5,PHC2,FAM13A,APH1A,PLEKHA1,RGS17,PAN3,DNAJC27,SIRPB1,NOP56,DISC1,NEU3,LOXL3,TDRKH,CCDC184,PCLO,GRIA2,ATE1,COQ10A,NME9,PAXBP1,MARK1,MAT2A,MBD1,MIA2,POC1B,CCDC13,DNHD1,OGG1,GPR137C,PDCD2,ZNF655,PURG,EXOSC10,SDK2,SH3KBP1,PPP3CA,CNNM2,WDR25,PTK2,SLC25A48,ENOX1,OXR1,C12orf49,EMID1,FAM214B,ZNF667,ANKRD36,ZC4H2,NKAIN2,RGL1,ADHFE1,MCF2L,SLC44A1,MTMR14,ERCC6L2,PRRT1,CDK20,SMUG1,AMACR,UBE2H,VLDLR,XRCC4,MICU3,ZNF189,MEIS3,CADM2,AMN1,FBXO36,NETO2" MicroRNA hsa-miR-634:mirSVR_highEffct hsa-miR-634:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.41E-44 5.26E-40 3.54E-43 3.26E-42 114 661 "PWWP2A,ESYT2,PTCHD1,ADRB2,AP2A2,OGT,IGDCC4,ATP2A2,TTLL9,BACH1,BBS2,MPDZ,JAZF1,CACNA1B,DDR1,CBLN1,NRXN3,CLCN3,AKAP12,CRYM,PDE4DIP,GIT2,DDX46,RHOBTB1,WDR20,PDCD6IP,DNM1L,EDN3,EDNRA,YAF2,PLEKHA1,ING4,ELN,PAN3,PIPOX,FAM198B,PCYOX1,IQCG,FLT1,POMT1,SMC2,UFM1,DBF4,GNAL,GPD2,LILRA2,GRIA2,ARHGAP36,INPP1,STXBP5,HECTD2,ZFYVE27,MBD1,SRSF12,BLOC1S2,LYRM9,IDNK,CCSER2,XRN1,PLCL1,LRP12,SEPT4,EPB41L4B,MINDY2,SNRK,PIGG,CNTLN,ANKHD1,TMEM260,PTPRG,RAD51D,RADX,REV3L,ZFHX4,SETD5,CARF,FBXW7,ATP8B4,KCNIP1,RTN1,ATXN7,SCN8A,CPEB3,SHC4,CNKSR2,PPP4R3A,SLC12A2,CPEB4,MYH15,MBD5,SNRPN,KDM4C,LMO3,CLASP2,TROVE2,ST5,DIP2A,ADHFE1,PRRC2C,ADAMTS17,SYN2,TBCEL,PCDHGA11,SYNE1,RPL7L1,BCL2L13,ZFP37,ZNF24,DHX33,NELFE,DOCK8,FRMD6,DPF3,ZNF30" MicroRNA hsa-miR-935:PITA hsa-miR-935:PITA_TOP PITA 9.58E-44 5.36E-40 3.60E-43 3.32E-42 76 282 "ABR,OSBPL6,PITPNM2,MAP4K3,APC,CDC14B,TMEFF1,CADPS,ATP1B3,CACNA2D2,MAP4K4,CS,CSNK1G3,SOCS5,DBN1,ALKBH8,GRIN3A,DMD,CDON,MBNL2,EIF4G2,EIF5,GPHN,GABRB3,GAD1,SESN1,GGT7,SPIN1,GLUL,MAP7D2,PTPRT,BACH2,MIER3,GABARAPL2,INSM1,KTN1,LIFR,LMO2,NCOA7,SMAD1,GPR155,MAT2A,MIA2,SCAMP5,GIT1,MYT1,NACA,CNOT4,KSR2,PDPK1,GPR85,OLA1,XRN1,PURG,LRRN3,RELN,PTPRD,SH3TC2,RADX,SLC25A36,FBXW7,FBXO11,FNDC3A,FAM81A,WDR47,CPEB4,FAM126B,SP2,CLSTN2,PRRC2C,ANKRD28,MGRN1,PUM2,TP53BP1,PLEKHH2,ZFAND5" MicroRNA hsa-miR-490-5p:mirSVR_highEffct hsa-miR-490-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-43 6.28E-40 4.22E-43 3.89E-42 119 720 "TAOK1,ARHGAP20,MARCH4,FAM135A,OGT,CDC42BPA,ANK2,PARG,APBA2,USP37,CADPS,PDE8B,RNF182,ADAM23,BACH1,ARHGEF7,CDH2,DCLK1,MAGI1,FAM19A5,MAP4K4,FHL5,SLC4A8,RCHY1,RIPOR2,ARHGAP24,LIN54,ARMCX4,CHRDL1,DMD,DNAH9,DTNA,GOLT1B,E2F6,EDN1,STARD3NL,TUBD1,GPHN,SRRM1,F8,SCML2,FGF14,PRKAG2,FLT1,TRMO,GABBR1,TUBGCP4,MSTN,ADAM28,MALT1,TXNL4A,TOX3,FERMT2,GRIA2,PRDM5,ZHX1,FRMD5,MIER3,IGFBPL1,ZIC5,SLC35G1,STXBP5,PAXBP1,MAT2A,MEIS2,NF1,LOC100128398,PFKFB2,SNX10,MTRF1L,EPB41L4B,HYDIN,SAMD9,VPS13C,WBP1L,TMEM260,PTPRD,RAP1GDS1,RIC8B,CARF,ROBO1,ATAT1,LRFN5,ZFP30,SH3GL3,FERMT1,FNDC3A,WDR37,CCDC88A,TET1,ANKRD36,MYCBP2,UNC5B,ZNF423,CLASP2,ERBIN,STAU1,SATB2,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RGMB,TRPS1,CA14,TSC1,RPL7L1,ZNF177,SMARCAD1,EMSY,RGS7BP,UBE3B,NLRP3,RNF170,FRMD6" MicroRNA hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA_TOP PITA 1.15E-43 6.43E-40 4.32E-43 3.97E-42 95 458 "ADCY6,PCDH19,OSBPL8,SPOP,OGT,DPP10,NCOA1,RNF182,CA8,CACNB4,DLGAP2,NUMBL,CHN1,B4GALT6,TMEM184B,ARMC8,IGDCC3,PUM1,SPOCK2,MYEF2,USP3,PHC2,YAF2,MBNL2,EGR3,TENM1,PAN3,EPB41L2,RASGRP2,ERBB4,SEC24B,MED12L,SYNCRIP,EVL,NBEA,KHDRBS3,GABRB3,MSTN,SPIN1,RAB30,KAT7,SOX21,PSIP1,SLC6A17,KCND2,IPO5,MAT2A,MKLN1,AFF1,SAMD5,MSI1,MYO5A,NTRK3,SDK2,PPP2R5E,RANBP3L,CEP41,GDPD1,GTDC1,FIGN,SPIN3,RPS6KA2,HUNK,KCNIP1,CLIP1,SEMA6D,MYO18A,CHD9,CPEB4,SNAP25,FAM126B,FAM219A,FNBP1,SOX11,LMO3,STAU1,NECAB1,PRRC2C,SYT1,ANKRD28,MCF2L,DICER1,CHST8,TIAM1,TSC1,OSBP2,ZIC1,NDRG4,SMARCAD1,SLC30A4,PRDM8,KAT6A,HNRNPA3,MSRB3,FXR1" MicroRNA hsa-miR-1:PITA hsa-miR-1:PITA_TOP PITA 1.17E-43 6.53E-40 4.38E-43 4.03E-42 86 371 "RALGAPA1,NDRG3,FMNL2,INTS2,HACE1,MAP4K3,BCL7A,FUBP1,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,RCAN2,EPHB1,SPEG,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,SMAP1,IGF1,INSM1,KIF2A,KTN1,MEIS1,GIT1,NEXMIF,GPR137C,ZNF827,TMOD2,TRHDE,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,SLC25A36,CARF,FBXW7,SEMA6D,MRAS,TRA2B,FNDC3A,SNAP25,TMCC1,SP2,LARP4,SYN1,MTCL1,TAL1,TRIM2,PUM2,DICER1,ZMAT3,SLC44A1,LRRC8A,FAM155A,UBE2H,TBC1D15,TMEM178A,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA hsa-miR-206:PITA hsa-miR-206:PITA_TOP PITA 1.17E-43 6.53E-40 4.38E-43 4.03E-42 86 371 "RALGAPA1,NDRG3,FMNL2,INTS2,HACE1,MAP4K3,BCL7A,FUBP1,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,RCAN2,EPHB1,SPEG,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,SMAP1,IGF1,INSM1,KIF2A,KTN1,MEIS1,GIT1,NEXMIF,GPR137C,ZNF827,TMOD2,TRHDE,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,SLC25A36,CARF,FBXW7,SEMA6D,MRAS,TRA2B,FNDC3A,SNAP25,TMCC1,SP2,LARP4,SYN1,MTCL1,TAL1,TRIM2,PUM2,DICER1,ZMAT3,SLC44A1,LRRC8A,FAM155A,UBE2H,TBC1D15,TMEM178A,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA "CTACCTC,LET-7B:MSigDB" "CTACCTC,LET-7B:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,MIR-98:MSigDB" "CTACCTC,MIR-98:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7C:MSigDB" "CTACCTC,LET-7C:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7G:MSigDB" "CTACCTC,LET-7G:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7F:MSigDB" "CTACCTC,LET-7F:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7A:MSigDB" "CTACCTC,LET-7A:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7I:MSigDB" "CTACCTC,LET-7I:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7D:MSigDB" "CTACCTC,LET-7D:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA "CTACCTC,LET-7E:MSigDB" "CTACCTC,LET-7E:MSigDB" MSigDB 1.24E-43 6.91E-40 4.61E-43 4.24E-42 85 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ZNF583,ADAM15,BACH1,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,DMD,CPEB2,SLC25A18,ARRDC4,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,DDX19B,SOWAHA,NKD1,NME4,NOVA1,PRTG,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,FNDC3A,WDR37,FAM214B,TRIM67,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,ANKRD28,KIAA0930,CDH22,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-miR-2276:mirSVR_highEffct hsa-miR-2276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-43 7.75E-40 5.16E-43 4.76E-42 125 793 "RALGAPA1,ACADM,NCKAP5,AP2A2,MTUS1,SPOP,ARHGAP20,AMPH,DPP10,ARNTL,CDK13,ALDH7A1,ADGRB3,DST,FUBP1,JAZF1,CALB1,MAGI1,MAP4K4,AKAP7,AKAP6,LETMD1,CNRIP1,CREM,PHACTR3,PHF14,CYBB,TCAF1,RIPOR2,MATR3,PABPC5,ZNF804A,FBXL5,PLPPR4,SV2B,KIF19,DYNC1I1,DMTF1,DPYSL2,ANKRD46,FAM13A,COPS4,DCTN4,COQ7,EYA1,GTF2IRD2,NELFCD,UFM1,STAMBP,ZNF605,ST6GALNAC3,PCDH17,TCERG1,TNRC6A,CBX1,ZNF782,GPD2,GRIA2,GRIN2D,ARHGAP36,HSF2,MSL1,ZNF181,GAREM2,RBPJ,LRRCC1,FAM69A,IPO5,PAXBP1,MBNL1,MEF2C,LYRM9,NEK1,NF1,SMIM11A,DUSP26,XRN1,EPB41L4B,DRAM2,PKIA,PRKCB,HYDIN,CNTLN,TMEM260,RDX,GTDC1,RGS12,ZNF532,EXD2,MCMBP,RYR3,SEMA6D,ATXN2,ATXN7,CASC3,COPZ1,SGK1,SH3GL3,SLC8A1,TET1,CPEB4,MYCBP2,KDM4C,DBNDD2,MPRIP,ADHFE1,KANK1,NSFL1C,ASTN2,DNMBP,WSCD1,SATB2,ZFP90,ZEB1,DOCK9,SIK3,ITGB3BP,FAM124A,ZIC1,EMSY,TMEM178A,FAM47E,RGS7BP,FAM219B,SENP7" MicroRNA hsa-miR-6867-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-43 7.82E-40 5.21E-43 4.80E-42 95 459 "PTCHD1,TAOK1,CARNS1,MARCH4,PCDH10,BCAS1,ARRB1,MARCH3,THSD7A,CALM1,RUNX1T1,CCNT1,CFL2,FOXN3,TMEM184B,IGLON5,AKAP12,SUSD5,PPP1R16B,PYGO1,DCAF8,DBT,JAKMIP2,TMEM130,SV2B,CHRDL1,DMD,CDON,DMTF1,KATNAL1,TBC1D16,FGF14,UBE2E3,EFCAB2,TRMO,C15orf41,MMADHC,GLI2,GLYR1,CBX1,BVES,SLC2A6,SYNPO,ZDHHC15,IGF1,NKD1,IL6ST,KCNB1,KLHL23,KCNN3,KCNQ3,SMAD9,MAP2,CHIC1,MITF,HS6ST3,MYO5A,NEXMIF,NELL2,OXTR,GPR173,NLGN3,ZNF655,CCSER2,PSAT1,SDK2,PRKCB,MAPK10,SH3TC2,RGS4,PGBD4,KIAA0895L,KCNIP3,SATB1,CSRNP3,PEX26,ZHX3,NMNAT2,ARHGEF9,PLCB1,ASTN2,MGRN1,ATMIN,ZEB1,TRIM2,THRA,NR2E1,DOK6,VSNL1,KCNK12,ELFN1,DPYSL5,STOX2,KAT6A,ZDHHC20" MicroRNA hsa-miR-3161:mirSVR_highEffct hsa-miR-3161:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-43 7.88E-40 5.24E-43 4.83E-42 129 842 "RALGAPA1,KCNH8,PTCHD1,BEND6,KIAA1324,AMPD3,DPY19L3,ATP6V1G2,BCL7A,NRP2,CBR1,MS4A7,NDST3,NRXN3,FAM19A5,AKAP6,ABI3BP,BAG4,CNRIP1,HAPLN1,RNF14,CRYM,CSNK1G3,SOCS5,DZIP3,PHF14,PLCXD3,HDAC9,TMEM170A,SNAP91,HS3ST2,DNAH9,EBF1,KLHL5,YAF2,PHF20L1,KMT5B,PLEKHA1,RRAGB,ACSL4,CEP78,FGF13,SUCO,ZBED3,ST6GALNAC3,RAPGEF6,ZNF559,DISC1,PPARGC1A,ZNF638,DIDO1,RNF165,NCKAP1L,ELOVL5,ZDHHC15,ZNF678,P2RY13,NCAM2,NEK1,NFE2L2,CNOT4,NOVA1,GPR137C,PCSK5,ENPP2,SNX10,PLIN1,PKIA,MAPK9,GDPD1,MASP1,SAMD9,PIGG,PTCH1,PTPRE,PTPRG,PTPRO,ZMAT4,RET,ERI2,RFX3,RGS12,RIC8B,ZNF532,ROBO2,LRRK2,ATAT1,CLIP1,RTN1,ZNF568,SALL1,ATXN7,LRFN5,SEC14L1,SUPT20H,FERMT1,CHD9,FBXO11,FHOD3,SEPHS1,GKAP1,IFT122,LMO3,NXT2,MPRIP,STXBP1,VPS13A,TACR1,KIAA1107,DMXL2,ZEB1,SYNE1,PCDHB7,NSD1,USP32P1,FAM200B,ERCC6L2,C9orf85,CLHC1,RPL7L1,RICTOR,TRIM9,ZNF540,SMARCAD1,EMSY,MPPE1,AMN1,NETO2,FAM198A" MicroRNA hsa-miR-613:PITA hsa-miR-613:PITA_TOP PITA 1.47E-43 8.20E-40 5.45E-43 5.02E-42 86 372 "RALGAPA1,NDRG3,FMNL2,INTS2,HACE1,MAP4K3,BCL7A,FUBP1,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,RCAN2,EPHB1,SPEG,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,SMAP1,IGF1,INSM1,KIF2A,KTN1,MEIS1,GIT1,NEXMIF,GPR137C,ZNF827,TMOD2,TRHDE,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,SLC25A36,CARF,FBXW7,SEMA6D,MRAS,TRA2B,FNDC3A,SNAP25,TMCC1,SP2,LARP4,SYN1,MTCL1,TAL1,TRIM2,PUM2,DICER1,ZMAT3,SLC44A1,LRRC8A,FAM155A,UBE2H,TBC1D15,TMEM178A,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA hsa-miR-514b-3p:mirSVR_highEffct hsa-miR-514b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.58E-43 8.86E-40 5.88E-43 5.42E-42 121 746 "KCNH8,PWWP2A,CDC14B,MARK4,NCOA1,BACH1,ADGRB3,SEC11C,JAZF1,CLGN,CHN2,TAOK2,RAB28,NRXN3,FAM149A,MYRIP,TRIM69,CSNK1G3,FAM169A,HDAC9,DGKB,PLPPR4,NR1D2,GOLT1B,E2F6,EGFR,PCOLCE2,VPS13B,SUCO,SYNCRIP,FLT1,SLC37A3,NSG1,B4GALNT1,SULT1C4,GLI2,DCLK2,LPAR4,GRIA2,GRM8,HNMT,ZNF491,CELF5,IDH3B,ITGAM,SLC35G1,KCNB1,LIG4,HECTD2,NCOA7,MATN3,MEIS2,POC1B,AFDN,ADAM22,MXI1,IDNK,NNAT,PCSK5,PLCL1,STRN3,TATDN3,SLC26A11,HYDIN,BDNF-AS,TMEM260,EML5,PTPRG,NWD1,ENOX1,KHDRBS2,RFX3,SLC25A36,TMLHE,CCDC102B,BAALC,ZC3H14,RTN1,SCN8A,PEAR1,FNDC3A,SEC31A,SEPHS1,NAPB,ZNF667,TTC17,SPP1,ERC1,ERBIN,ZSCAN29,ARHGEF9,VPS13A,C12orf76,TBCEL,SIN3B,TCF12,USP22,SZT2,PCDHB6,TEK,ITGB3BP,CDH22,NACC2,TPM1,ZNF346,METTL3,TTTY15,EIF4ENIF1,UGT8,RBFOX3,ZNF142,FSTL5,EML6,SLC30A4,MFF,MDH1B,NAV3,KCNAB1,HNRNPA3,RNF170,NETO2" MicroRNA hsa-miR-145:PITA hsa-miR-145:PITA_TOP PITA 1.70E-43 9.49E-40 6.30E-43 5.80E-42 89 401 "FMNL2,USP31,HECW2,RTL9,OSBPL1A,SEMA6A,SPOP,FAM135A,EPB41L5,PPFIA3,ZBTB10,SYNJ1,THSD7A,CDH2,CFL2,QKI,MAP4K4,CABP1,TBPL1,AKAP12,ARHGAP24,YTHDC1,ELMO1,ZC3H11A,ALKBH8,MTX3,WDR20,NR1D2,DPYSL2,RCAN1,TENM1,GPHN,ERBB4,ACSL4,FGFR3,AFF2,ST6GALNAC3,FUT9,GGT7,KDM2B,GPD2,GRB10,C1QL4,FAM19A2,BACH2,GABARAPL2,ZNF181,MEST,MYO5A,MYO6,NEXMIF,NRCAM,XRN1,PPP3CA,PRPSAP2,TMEM255A,SH3TC2,REV3L,SLC25A36,ZFHX4,CARF,CCDC25,ATXN2,KIF21A,CPEB3,FNDC3A,NLGN1,FAM81A,CPEB4,SOX11,PEG10,ZNF423,POGZ,ANKRD28,TCF4,TRIM2,DOCK9,CRTC1,FRYL,HEY1,TP53BP1,DOK6,UBTF,TBC1D15,PCDH20,ZNF138,TMEM178A,NAV3,RNF170" MicroRNA hsa-miR-3166:mirSVR_highEffct hsa-miR-3166:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-43 1.01E-39 6.71E-43 6.18E-42 135 919 "CLK4,DPY19L2P4,AP2A2,INTS2,KCTD16,ZNF578,ALCAM,OGT,VAT1L,MARCH3,NCOA1,ATP2B2,RGS9,ARHGEF7,BAIAP3,CACNA1B,KALRN,ZMYM4,TIGD7,MS4A7,TPP1,SULT4A1,AKAP7,COL9A1,LETMD1,SLC4A8,FAM171B,PREPL,RNF14,SNCAIP,CSF2RA,SEC24C,OSBPL3,ERC2,UBXN2A,GAPVD1,ZNF582-AS1,USP3,CPEB2,DTNA,ANKRD46,CELSR3,EGR3,GOLGA7,GPHN,CEP85L,ADGRV1,EYA1,FCGRT,FHL1,SUCO,SYNCRIP,NOP56,ATP2C1,NSG1,GABBR1,FAM120B,RAPGEF6,DISC1,SPIN1,RAB30,DCLK2,FERMT2,PCLO,STMN2,GRM2,RABL2A,HMGCR,MEIS1,NPR2,IGSF11,CLDN11,GPR137C,PDE4B,NALCN,FAM218A,XRN1,BDNF-AS,TMEM260,MARCH1,CEP97,RAP1GDS1,OXR1,FIGN,MRPS18A,NUDT11,PNMA8A,GSTCD,KIRREL1,RORB,RPL15,MEG3,SEMA6D,SATB1,SMPD3,COPZ1,SCAF8,KIF21A,CPEB3,SHC4,WDR37,WDR47,KBTBD4,CPEB4,INTS9,UHRF1BP1L,KDM4C,ZNF423,RBM26,ERBIN,CAMTA1,ZEB1,PCDHB9,FRYL,RNF216P1,SLC44A1,MTMR14,HEY1,KAT6B,PIK3R5,RGMB,SSBP2,TTC3,PCDH20,ZNF19,TCEAL7,FSTL5,EMSY,LINC02210,WNK3,RGS7BP,FZD3,TIGD6,FRMD6,RNF146" MicroRNA hsa-miR-125b-5p:TargetScan hsa-miR-125b-5p TargetScan 1.85E-43 1.04E-39 6.86E-43 6.32E-42 113 654 "ASIC1,ACHE,ABHD6,NDRG3,ADD2,LRFN2,MTUS1,PKP4,APC,BMPR1B,MTMR3,ARHGEF1,SCARB1,NUMBL,FOXN3,B4GALT6,QKI,COL11A2,BAG4,ENTPD4,HAPLN1,HINFP,ANKRD44,NCOR2,PHACTR3,FAM131B,IST1,IP6K1,DNAL1,ELMSAN1,DCTN1,RUSC2,FAM107B,ABCC5,PHC2,HIPK3,CNNM1,ERBB2,ERBB4,CORO2B,FGF14,FGFR1,C2orf88,CGREF1,KIAA1841,GGT7,LPAR4,GRB10,BTN2A1,GSTM5,ATOH8,FRMD5,MAN1B1,HMGCR,HNF4G,MSL1,IL6R,ITGA7,KCNB1,LIFR,MBD1,ADAM11,MEIS2,MSI1,SAMD14,MYO9A,MYT1,IGSF11,CHAMP1,KCTD15,DRAM2,MAPK10,CNNM2,PTH1R,C1orf109,FAT4,RASGRF1,RASGRF2,DPF2,RFX3,LGI2,RORB,EMID1,KCNIP3,MAPK12,CSRNP3,ATXN7,SCN2B,COPZ1,CPEB3,MYO18A,CPEB4,ABTB1,FAM126B,KDM4B,CDK19,ELOVL4,SATB2,CRTC1,DICER1,ASXL3,NPL,CLIP2,KLC2,CRB2,LYPD6,POLR3H,DHX33,GDPD5,PARP11,RGS7BP,MSRB3,LAS1L" MicroRNA hsa-miR-125a-5p:TargetScan hsa-miR-125a-5p TargetScan 1.85E-43 1.04E-39 6.86E-43 6.32E-42 113 654 "ASIC1,ACHE,ABHD6,NDRG3,ADD2,LRFN2,MTUS1,PKP4,APC,BMPR1B,MTMR3,ARHGEF1,SCARB1,NUMBL,FOXN3,B4GALT6,QKI,COL11A2,BAG4,ENTPD4,HAPLN1,HINFP,ANKRD44,NCOR2,PHACTR3,FAM131B,IST1,IP6K1,DNAL1,ELMSAN1,DCTN1,RUSC2,FAM107B,ABCC5,PHC2,HIPK3,CNNM1,ERBB2,ERBB4,CORO2B,FGF14,FGFR1,C2orf88,CGREF1,KIAA1841,GGT7,LPAR4,GRB10,BTN2A1,GSTM5,ATOH8,FRMD5,MAN1B1,HMGCR,HNF4G,MSL1,IL6R,ITGA7,KCNB1,LIFR,MBD1,ADAM11,MEIS2,MSI1,SAMD14,MYO9A,MYT1,IGSF11,CHAMP1,KCTD15,DRAM2,MAPK10,CNNM2,PTH1R,C1orf109,FAT4,RASGRF1,RASGRF2,DPF2,RFX3,LGI2,RORB,EMID1,KCNIP3,MAPK12,CSRNP3,ATXN7,SCN2B,COPZ1,CPEB3,MYO18A,CPEB4,ABTB1,FAM126B,KDM4B,CDK19,ELOVL4,SATB2,CRTC1,DICER1,ASXL3,NPL,CLIP2,KLC2,CRB2,LYPD6,POLR3H,DHX33,GDPD5,PARP11,RGS7BP,MSRB3,LAS1L" MicroRNA hsa-miR-320e:mirSVR_highEffct hsa-miR-320e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.13E-43 1.19E-39 7.89E-43 7.26E-42 117 701 "NDRG3,AGT,PKP4,CDK13,STK33,ASPA,NCOA1,BACH1,ARHGEF7,IL33,CA8,SLC25A14,CAST,SPAG9,CCNH,CDC25B,TIGD7,EPS15L1,PPT2,LETMD1,BAG4,CNRIP1,CLOCK,AKAP12,GDA,SEC24C,PHF14,PNPLA8,CYBB,GIT2,ARMCX2,MYEF2,DYNC1I1,MAMLD1,AASDH,RASGRP1,FAM13A,SUGP2,MBNL2,PLEKHA1,CDKL3,ST3GAL6,POLR1B,FGF11,POMT1,UFM1,PDLIM5,PRELID3A,AP4B1,TUBGCP4,ADAM28,GGTA1P,DBF4,MAP7D2,MCHR1,LINC01089,RNF165,PSIP1,ADAMTS6,TNFAIP8L3,LAMP2,PAXBP1,CLEC18A,MAT2A,AQP11,MBD1,MEIS2,KITLG,MXI1,NF1,NFE2L2,ALDH1L2,NINJ2,VWA2,OGG1,CDK18,PDE3A,NALCN,RETREG1,MTRF1L,PLXNB1,PPP2R2C,CEP41,CNTLN,RFX3,SETD5,TMLHE,PNMA8A,DGLUCY,SEMA6D,FOXRED1,R3HDM2,CNKSR2,DHX30,SLC8A1,SLC14A1,IFT122,ANKRD36,ERC1,POGZ,COBL,ANKRD28,EXOC7,TCEA1,CLASP1,PUM2,TPM1,SMUG1,UBE2H,LMF1,KCNT2,CELF4,ANKS1B,NAV3,EPM2A,PHTF2,LAS1L" MicroRNA hsa-miR-106b-5p:Functional MTI Functional MTI miRTarbase 2.48E-43 1.39E-39 9.18E-43 8.45E-42 148 1091 "FMNL2,ADD1,FZD9,SORCS2,ZNF578,MARCH4,SEMA7A,APC,ATP1B3,LDHD,ARHGEF7,MTMR3,RUNX1T1,CBFA2T2,ZBED1,DIS3L,CFL2,EPS15L1,CLTC,QKI,IGDCC3,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,SOCS5,UBXN2A,CYBB,DCAF8,ZFYVE16,DNAL1,YTHDC1,ELMSAN1,FBXL5,SACS,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,GOLT1B,E2F5,FEM1B,KMT5B,EIF4G2,IRAK4,CERCAM,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,TPK1,FYN,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,MMADHC,CRCP,RNPS1,RAB30,TNRC6A,CBX1,LUZP2,FUT10,CIT,KAT7,FICD,HAS2,HMGCL,ITPKB,KCNB1,CAMK2N2,SMAD9,PIK3AP1,GPR155,MAT2A,CHIC1,SCAMP5,AFF1,MXI1,NBL1,NEFH,CNOT4,OCRL,PDPK1,PFKFB2,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PPM1B,KANSL1,PRKACB,PRKCB,MAPK9,VPS13C,CEP97,OXR1,ZNF532,ATAT1,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,BTBD7,CMTR2,FAM126B,FNBP1,SP2,SP4,STAC2,ANKRD12,CAMTA1,TCF4,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,TMPO,PARD3,RGMB,NR2C2,PDSS1,TSC1,UBC,ZNF70,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-148a:PITA hsa-miR-148a:PITA_TOP PITA 2.83E-43 1.58E-39 1.05E-42 9.64E-42 97 483 "ASIC1,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,MARCH3,NCOA1,ADGRB3,BCL7A,SYNJ1,CALM1,CAMK2A,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,RUBCN,SNAP91,RAB39B,DMPK,KLHL5,FRY,EGR3,SLC43A2,EZH1,SCML2,MED12L,PRKAG2,C15orf41,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,KIT,STXBP5,MITF,NDP,NFIX,NPTX1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,PIK3C2A,ANKRD16,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,SCN2B,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,PLCB1,SYT1,TCF4,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TRPS1,TMEM237,SLC38A1,RTN4,KAT6A,FXR1,JPH3" MicroRNA hsa-miR-1321:mirSVR_highEffct hsa-miR-1321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.83E-43 1.59E-39 1.05E-42 9.65E-42 128 835 "VWA5B2,KLHL13,AK2,SPOP,ZNF687,LRFN1,OGT,LCORL,TMEFF1,ARHGDIG,TMEM108,ATP6V1G2,MYOM1,CFAP410,RUNX1T1,ARHGEF1,MAGI1,QKI,ARHGEF6,COL9A1,LETMD1,ZNF385A,ENTPD4,CS,SNCAIP,ARHGEF10,CSNK1E,OSBPL3,ZNF337,SPOCK2,AIF1L,ARMCX4,MYEF2,ELMO1,FBXL5,GRIN3A,DNM1,ABCC5,E2F6,AASDH,APH1A,EPHB1,DENND4A,MRPL10,SIRPB1,NRN1,ZNF461,TAOK3,OLFM1,ANKFY1,TRMO,PDLIM5,GABRG2,DISC1,INPP5K,TUBA8,SRCAP,GLYR1,LPAR4,SERP2,KAT7,RNFT2,TOX2,FRMD5,HSPA1L,LRRTM1,NME9,KHK,KIF5A,MAT2A,NPR2,DPY19L2P2,CDK18,PIK3C2A,PURG,PMP22,RASGEF1B,HYDIN,PRPSAP2,PTK2,PTPRG,PTPRO,SLC25A48,RAP1GDS1,ZNF493,HKR1,PRRT2,RGS3,RNASE1,RIC8B,C12orf49,RYR3,NCBP3,SARS,ATXN2,CASC3,COPZ1,FERMT1,SEC31A,EPN2,WDR47,SIRT2,CCDC88A,ATF7IP,SP2,NFASC,ZNF302,SS18,ZFP90,PCDHB9,TNS2,CYB561A3,AP4E1,AKTIP,KCNE5,SSBP2,FAM155A,BCL2L13,WIPF1,ZIC2,ZNF177,MEIS3,STOX2,RNF103,RGS7BP,GJC2,RNF170,PRRT4" MicroRNA hsa-miR-26a:PITA hsa-miR-26a:PITA_TOP PITA 2.96E-43 1.66E-39 1.09E-42 1.01E-41 96 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SLC4A4,FUBP1,CACNB4,CALM1,SRSF11,FOXN3,SOCS6,CHN2,TMEM184B,CNR1,AKAP7,SOCS5,ERC2,PLCXD3,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,DMD,USP3,EIF4G2,EIF5,PAN3,FKTN,MEX3B,SRCAP,TNRC6A,GRB10,ADAMTS6,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PFKFB3,FAM98B,GPSM2,PLCL1,PCDH18,FA2H,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,CLASP2,LARP4,STAC2,PLCB1,FAM208A,AMACR,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK3,PHTF2" MicroRNA hsa-miR-26b:PITA hsa-miR-26b:PITA_TOP PITA 2.96E-43 1.66E-39 1.09E-42 1.01E-41 96 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SLC4A4,FUBP1,CACNB4,CALM1,SRSF11,FOXN3,SOCS6,CHN2,TMEM184B,CNR1,AKAP7,SOCS5,ERC2,PLCXD3,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,DMD,USP3,EIF4G2,EIF5,PAN3,FKTN,MEX3B,SRCAP,TNRC6A,GRB10,ADAMTS6,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PFKFB3,FAM98B,GPSM2,PLCL1,PCDH18,FA2H,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,CLASP2,LARP4,STAC2,PLCB1,FAM208A,AMACR,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK3,PHTF2" MicroRNA hsa-miR-1297:PITA hsa-miR-1297:PITA_TOP PITA 2.96E-43 1.66E-39 1.09E-42 1.01E-41 96 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SLC4A4,FUBP1,CACNB4,CALM1,SRSF11,FOXN3,SOCS6,CHN2,TMEM184B,CNR1,AKAP7,SOCS5,ERC2,PLCXD3,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,DMD,USP3,EIF4G2,EIF5,PAN3,FKTN,MEX3B,SRCAP,TNRC6A,GRB10,ADAMTS6,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PFKFB3,FAM98B,GPSM2,PLCL1,PCDH18,FA2H,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,CLASP2,LARP4,STAC2,PLCB1,FAM208A,AMACR,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK3,PHTF2" MicroRNA hsa-miR-1264:PITA hsa-miR-1264:PITA_TOP PITA 3.10E-43 1.74E-39 1.14E-42 1.05E-41 94 453 "USP31,SEMA6A,SRPX,OGT,APBA2,TMEFF1,CDK13,STK33,ADGRB3,JAZF1,THSD7A,ZMYM4,SRSF11,FOXN3,CNOT8,SLIT2,NRXN3,QKI,ARHGEF6,CNR1,AHCTF1,CS,SOCS5,APPL1,SCRN1,ARMCX2,DYNC1I1,EGR3,TMEM132E,EIF5,STARD3NL,PAN3,CLVS1,FGF13,SUCO,ANKFY1,AFF2,FAM49B,GABRB3,SPIN1,GNAO1,GRIA2,FAM19A2,AGFG1,SMAP1,LRRCC1,SLC35G1,KCNN2,NCOA7,AQP11,CHIC1,LRP1B,MEIS2,MYO5A,MYO7A,NEXMIF,NDP,PRTG,GPR85,XRN1,PTK2,TMEM260,PTPRO,MSANTD2,REV3L,PRRT2,ZFHX4,SETD5,RORB,FBXW7,KCNIP1,ATXN2,TRA2B,CPEB3,FBXO11,NLGN1,PPP4R3A,CPEB4,SOX11,NFASC,ITPRID2,SYNE2,FBXW11,SATB2,TCF12,DOCK9,ZFPM2,SGK3,ZBTB14,KCNT2,ZFAND5,SLC38A1,RNF103,SOCS4" MicroRNA hsa-miR-200c*:mirSVR_highEffct hsa-miR-200c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.80E-43 2.13E-39 1.40E-42 1.29E-41 102 537 "GALNT13,BEND6,NME5,HFM1,SPOP,USP35,SRPX,PCDH10,CDC42BPA,PPP4R4,ZSCAN18,NUMB,CA8,RUNX1T1,ZNF501,SLC16A4,COL9A3,C2CD2,CRHBP,VCAN,SOCS5,APPL1,KATNAL2,IST1,PITPNC1,RHOBTB1,DTNA,HIPK3,FRY,FAM13A,PHF20L1,EPB41,NCALD,EYA1,ZNF585B,DLC1,SYNCRIP,OGA,MTHFD2,DISC1,PCDH17,KDM2B,GNAO1,TOX2,ZDHHC15,INSM1,ITPKB,KCNJ16,KCNN2,KIF2A,STXBP5,LMO2,HECTD2,MAT2A,MBNL1,EFHB,SHC3,MEF2C,MEIS1,SRSF12,KITLG,MID1,AFDN,IDNK,GPR137C,CNTN3,PCDH8,PDE4D,ZNF655,FAM218A,PRPSAP2,VPS13C,FAM184A,HKR1,CRTAC1,CARF,RORB,PCMTD2,ZNF568,CSRNP3,NUBPL,SNRPN,SAMSN1,DIP2A,ARHGEF9,PLCB1,C12orf76,TBCEL,TCEA1,SATB2,DOCK9,USP32P1,SIRT1,TMPO,RUNDC3B,SGK3,GUSBP1,TRIM9,ZFAND5,EMSY,PHTF2,MSRB3" MicroRNA hsa-miR-548q:mirSVR_highEffct hsa-miR-548q:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.80E-43 2.13E-39 1.40E-42 1.29E-41 102 537 "ABHD6,NCKAP5,ADD2,RNF150,ZNF608,SPARCL1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,STK33,ADGRB3,BARD1,SEC11C,CALB1,KALRN,CBR1,LDB2,SEPT7,ZMYM4,RCBTB2,CLTC,SNCAIP,SEC24C,ARHGEF10,OSBPL3,RIMS2,BOC,ARHGAP32,RIPOR2,IP6K1,WDR20,DNAH9,ABCC5,EBF1,COPS4,PAN3,MFSD10,EPB41L2,SIRPB1,GMPR2,F5,ZSCAN30,KAT8,BAIAP2,NOP56,NBEA,STAU2,OGA,B4GALNT1,GHDC,DISC1,GCNT2,TNRC6A,BTN2A1,RNF165,SMAP1,MSL1,FAM69A,KCND2,KPNA5,CYP27C1,MARK1,MAT2A,NTRK3,ZNF827,GNG2,ZNF655,PCDH18,PRIMPOL,ING3,MAPK9,RET,MORC4,RNASEL,SETD5,ABCA11P,ST6GALNAC6,CLIP1,DGLUCY,FNDC3A,PPP4R3A,SLC12A2,ZSWIM8,RBM26,STAU1,ZSCAN29,ADHFE1,CAMTA1,ITGB3BP,FAM124A,R3HDM1,C9orf85,METTL3,LMF1,ZNF781,ZNF711,ZNF19,KCNT2,TRIM9,LYPD6,LAMP5,SMIM8,PHTF2" MicroRNA hsa-miR-875-5p:mirSVR_highEffct hsa-miR-875-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.62E-43 2.59E-39 1.70E-42 1.57E-41 115 683 "KCNH8,CCDC85A,RNF150,ESYT2,ALCAM,PARG,EPB41L5,UPRT,PPP4R4,ADGRB3,NRP2,LRBA,FHL5,AKAP6,SLC4A8,ABI3BP,RCHY1,TRIM69,PHF14,USP6NL,CCDC144A,CYBB,HDAC9,GAPVD1,RIPOR2,DGKB,DDX46,FAM107B,DYNC1I1,DTNA,E2F5,RASGRP1,FRY,PHF20L1,EGFR,EYA1,FAM198B,SH3YL1,ACSL4,TAOK3,CEP78,CHST15,NELFCD,ATP2C1,ABLIM2,MEGF11,NEU3,RNF165,NEGR1,LRRCC1,NCOA7,AQP11,MKLN1,ZNF680,NFE2L2,NUCB2,IGSF11,CLDN11,PDE4D,ABCB1,RETREG1,STRN3,SH3KBP1,TATDN3,PRKACB,PRKCB,MASP1,CNTLN,PTN,RASGRF2,ERI2,SETD5,SPIN3,ATP8B4,LRRK2,CCDC112,SALL1,SCP2,MRAS,FAM102A,PPM1E,FHOD3,SYBU,PPP4R3A,RCOR3,LIMCH1,PDZD2,SP2,MCF2L2,RBM26,TROVE2,ITPRID2,SSTR1,CEP68,SYNE2,SYPL1,MTCL1,ATMIN,SATB2,SYNE1,NSD1,SIK3,ZFPM2,AKTIP,TIAM1,MTMR14,ASXL3,SYNPO2,TRIO,WIPF1,PCDH20,ZNF74,FSTL5,SMIM8,PHTF2" MicroRNA hsa-miR-3187:mirSVR_highEffct hsa-miR-3187:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.85E-43 2.72E-39 1.79E-42 1.64E-41 109 615 "RALGAPA1,SYS1,KCTD16,OSBPL8,PCDH10,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,BCAS1,PLA2G4C,DPY19L3,ADGRB3,DST,SYNJ2,VXN,CFL2,RAB33A,TPP1,CNTN1,SLC4A8,ZFP28,CRHBP,CS,VCAN,VAC14-AS1,CTH,RUBCN,RIPOR2,LONRF1,DBI,YTHDC1,MYEF2,WDR20,DNM1,USP3,E2F5,EDN1,EDNRB,C8orf37,CDKL3,F8,RACK1,FER,FGF1,FGF11,POLK,MSANTD4,OGA,GABRA3,RAPGEF6,PPARGC1A,GLUL,ZNF638,LOXL3,LNX1,GPD2,HSF2,STXBP5,SMAD1,MAP6,MATN2,MBNL1,NUCB2,OGG1,GPR85,CCSER2,GPSM2,PLCL1,PLIN1,PDZRN4,CEP41,MAPK4,HYDIN,SPDL1,RADX,TCP11L1,MAP6D1,ZNF331,ATXN7,SCN7A,SH3BP2,FRMPD1,ASAP3,ATF7IP,CDK5RAP2,MYH15,SNRPN,SPATA7,SP4,ERBIN,ZSCAN29,VPS13A,TMEM150C,TACC1,TBL1X,SIRT1,C18orf54,WBP2,AMACR,TRO,PPIL6,UGT8,VLDLR,TRIM9,ZNF540,PRDM10,NELFE,TRAM2-AS1" MicroRNA hsa-miR-940:mirSVR_highEffct hsa-miR-940:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.47E-43 3.06E-39 2.01E-42 1.85E-41 124 791 "SYS1,TMCC3,GALNT13,PTCHD1,ZNF608,KIAA1324,SPOP,CEP126,DOC2A,SUGT1P4-STRA6LP-CCDC180,UPRT,TNRC6C,CHRD,N4BP2L1,DPY19L3,CFAP410,CFL2,TPP1,FAM149A,LETMD1,HAPLN1,ANKRD44,CS,SIPA1L1,APPL1,DCAF4,GAPVD1,SV2B,SGSM2,SLC12A6,ABCC5,EDIL3,EDNRB,YAF2,TNK2,STARD3NL,RASGRP2,STX2,SIRPB1,ACSL4,PRMT5,FAM49B,CAMKK2,TPPP3,ABLIM2,INPP5K,ADAM28,CBX1,CCDC184,STMN2,HAS2,ICA1,RBPJ,IL6ST,KCND2,KCNK3,PIK3AP1,LYPLAL1,MATN2,MYO9A,CCDC13,NF1,NME4,SLC11A2,NTRK2,NTRK3,NUCB2,PFKFB2,SMOX,TRHDE,SCHIP1,EPB41L4B,PPM1B,BDNF-AS,PTK2,PTPRE,PTPRH,PTPRN,ENOX1,MORC4,SLC25A36,DCUN1D2,ARMC5,CARF,ATP8B4,DGLUCY,CASC3,ZNF821,CCDC92,PPP4R3A,KANSL3,PKNOX2,RCOR3,SNRPN,PDZRN3,ZC4H2,ZSCAN29,ZC3H4,SYN1,SYNE1,FAM189A1,USP32P1,GPRIN3,SIRT1,ZMAT3,ARL10,HEY1,PRRT1,TPM1,NPL,METTL3,TRIO,TTTY15,CCDC136,CCDC14,CFAP298,FTSJ1,ZNF225,CADM2,MDH1B,EPM2A,CASC15,NHSL1,AP3B2" MicroRNA hsa-miR-155-5p:Functional MTI Functional MTI miRTarbase 6.50E-43 3.64E-39 2.39E-42 2.20E-41 133 904 "FMNL2,TBC1D14,FAM135A,LCORL,APAF1,APC,BACH1,FUBP1,CARS,CDH2,CFL2,SOCS6,CLTC,CDC42BPB,CS,CSF1R,PHF14,PNPLA8,DOCK4,GAPVD1,MATR3,DBN1,CHRDL1,DMD,DMTF1,GOLT1B,EDN1,PHC2,KLHL5,EGFR,KCTD3,EIF4G2,C3orf18,EPB41L2,EZH1,F5,FDFT1,SEC24B,POLR1B,PCYOX1,FOXO3,FLT1,ANKFY1,SPECC1,PDLIM5,ATP6V1H,SARAF,GALC,MTHFD2,KIAA1841,GATM,ARFIP1,SPIN1,RAB30,GPT2,PSIP1,PACSIN2,ACOT7,RBPJ,ZNF678,KCNN3,KPNA5,PAXBP1,SMAD1,TM6SF1,MEIS1,MEST,MIA2,MITF,MKLN1,MMP16,MOV10,MPP2,MXI1,MYO6,NOVA1,SLC11A2,PCDH9,PDE3A,FAM98B,PIK3R1,STRN3,PSAT1,KANSL1,PPP5C,CEP41,PKIA,FITM2,WBP1L,QRICH1,PTN,ZNF493,PBRM1,CCDC82,DCUN1D2,FBXW7,RPS20,HSPA4L,CHD9,CDK5RAP3,SLC12A4,CPEB4,SMARCA4,KDM3A,TROVE2,ERBIN,RGL1,SUPT5H,SYNE2,SYPL1,ANKRD12,CAMTA1,EXOC7,TCEA1,TCF4,TCF12,SIRT1,ARL10,TRIO,TRPS1,ZKSCAN5,UBE2H,UGT8,LAT2,RICTOR,XPO1,ZNF28,ZBTB38,MFF,CIAPIN1,VPS35L,FIP1L1,HNRNPA3" MicroRNA hsa-miR-675*:mirSVR_highEffct hsa-miR-675*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.70E-43 3.75E-39 2.46E-42 2.26E-41 103 551 "KLHL32,GALNT13,KIAA1211,PTCHD1,BEND6,OSBPL1A,PCDH10,FAM135A,CDC42BPA,CCDC146,PKP4,APC,CDK13,ASPA,ZBTB10,INSYN2B,N4BP2L1,BID,DST,SYNJ1,SYNJ2,WASF1,PTBP2,MAGI1,CLGN,CHN2,RAB33A,C4orf33,ZFP28,SEC24C,VCAN,SCRN1,GSDME,DDX46,DMTF1,PDCD6IP,WDPCP,HIPK3,YAF2,C3orf18,ENPP6,SLC9B2,SUCO,FOXO3,ATP2C1,CSPG5,SYT17,DBF4,ATP2B1-AS1,GSTT2,IL6ST,JAK2,CREG2,NCOA7,LYPLAL1,MBP,MEIS1,SRSF12,MITF,BLOC1S2,ADAM22,NRCAM,DPY19L2P2,PDCD2,PLCL1,EPB41L4B,PPM1B,DIRAS2,VPS13C,PTPRO,ZDHHC14,RGS4,ELP2,NEK11,RPL15,SCP2,TNFRSF19,SH3GL3,PPP4R3A,TET1,CPEB4,ZFP1,RCOR3,MBD5,BDP1,KDM4C,LMO3,ELOVL4,SYNE2,ATMIN,ZEB1,TCF12,DICER1-AS1,AP4E1,SLC44A1,NR2E1,ERCC6L2,UBE2H,ZIC2,ZNF711,MICU3,TRIM9,UPF3A" MicroRNA hsa-miR-24-1*:mirSVR_lowEffct hsa-miR-24-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.38E-43 5.25E-39 3.44E-42 3.17E-41 124 795 "ASPHD1,ADORA2A,OLMALINC,OSBPL8,SYT13,CDC42BPA,LRCH2,APAF1,APC,TNRC6C,CDC14B,IGDCC4,SPTBN4,STK33,RIPK1,PTBP2,CAMK2A,CAST,P2RX6,ARHGEF2,LRRFIP1,SEC31B,RBM39,SNCAIP,DZIP3,ARHGAP32,MATR3,IP6K1,AIF1L,HEPH,RHOBTB1,EXOG,DNAH9,E2F6,EDIL3,CERCAM,RCAN2,ENPP6,RRAGB,FAM198B,CEP78,SYNCRIP,IQCG,ATP6V1H,ZNF605,DISC1,DBF4,TNRC6A,LILRB4,GPD1,FAM107A,NCKAP1L,ARHGAP36,ELOVL5,LRRC75A,FAM95B1,IL6ST,TTYH2,HECTD2,MEIS1,SCAMP5,MN1,MPP2,N6AMT1,MYO7A,P2RY1,GLIPR1L2,GPR173,GPR85,ZDHHC8,GPSM2,NLE1,PLCB2,PPP2R5E,PRKAB2,TMEM104,PTN,PTPRE,SUSD4,RDX,SLC25A36,RORB,NEK11,KIAA0895L,ABCA11P,KCNIP3,ZNF568,TRAPPC13,ATXN2,PEAR1,MRAS,FNDC3A,PEX26,WDR47,CCDC88A,KBTBD4,DOP1A,ZC3H13,DBNDD2,SPTB,ZBTB43,NFASC,PBLD,ELOVL4,ADAMTS17,SYN2,SYP,SYPL1,CAMTA1,ATMIN,SLC44A1,TMPO,FAM124A,TP53BP2,CHST5,TRIO,TRPS1,PPIL6,SSBP2,FLRT2,ZNF154,PCBP1-AS1,VPS35L,FZD3" MicroRNA hsa-miR-147:mirSVR_highEffct hsa-miR-147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.43E-43 5.28E-39 3.46E-42 3.18E-41 118 723 "ABHD6,ADD2,AXIN2,FAHD2CP,BEND6,KCTD16,AMPH,ZFAT,ANK2,MAP4K3,MYH7B,PKP4,PARG,FAM131A,LINC00847,BID,KALRN,CAST,CCK,LDB2,CBFA2T2,CHGB,CHN2,RAB28,AKAP6,AKAP12,SNCAIP,CSNK1E,CYBB,DCAF8,SPOCK2,MYEF2,FBXL5,DMTF1,EDN1,KMT5B,RGS17,RABEPK,MRVI1,F5,F8,FAM198B,RACK1,FDFT1,MEX3B,NOP56,ERAP1,SYT17,DISC1,TUBGCP4,COPS8,ZNF638,MAP7D2,PRUNE2,HSF2,IL6ST,ITGAM,CDH20,CYP27C1,L1CAM,LMO2,HECTD2,MAT2A,POC1B,MSR1,NF1,LOC100128398,ZNF827,PCDH8,PDE1C,ENPP2,ZDHHC8,PLCL1,PCDH18,PURG,PPM1B,HYDIN,MASP1,GDPD2,CNTLN,STK32A,PTPRD,PTPRG,ACSM5,FAM66C,RAP1GDS1,RASGRF2,RGS3,NUDT11,PBRM1,TMLHE,ROBO2,CCDC102B,ATP8B4,SARS,TNFRSF19,FERMT1,SYBU,PPP4R3A,ELMO2,ATF7IP,TET1,SYNE2,CAMTA1,KLHL4,RPGRIP1L,GPRIN3,SLC44A1,TP53BP2,RGMB,TRO,HSPBP1,HIRA,ZNF28,TRIM9,RTN4,PHTF2,CPNE4" MicroRNA hsa-miR-4252:mirSVR_highEffct hsa-miR-4252:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.47E-43 5.30E-39 3.47E-42 3.19E-41 108 608 "ASPHD1,KDM5D,NDRG2,MTUS1,HACE1,OSBPL1A,HFM1,PHF12,UPRT,BCAS1,LGR5,ZNF583,ADAM23,BACH1,LINC00847,KSR1,BMP7,ARHGEF7,BTK,WASF1,CA8,KALRN,LDB2,RAB28,C4orf33,IQCK,FAM149A,AKAP6,LETMD1,TBPL1,ANKRD44,RGS6,ARHGEF10,KIAA0040,CTH,ZFYVE16,LONRF1,SCRN1,DDX46,SV2B,WDR20,DNAJB6,GOLT1B,EDN1,EDNRB,ANKRD46,RASGRP1,EGFR,EPHB1,SPEG,FAM198B,PCYOX1,SLC37A3,JKAMP,OGA,TUBGCP4,RNPS1,GPR75,TNRC6A,ZNF638,KCNMB4,GRIA2,GRM2,KAT7,ZBTB49,AGBL5,IL6ST,LRRTM1,SLC35G1,KIT,LAMP2,MAP4,MBNL1,MEIS1,MMP16,NRBP2,NF1,NINJ2,LOC100128398,P2RX7,PCDH9,PFKFB2,JAKMIP1,ING3,PPP1R1A,TATDN3,RELN,RFX2,FBXW7,SPIN3,FNDC3A,HECW1,MESP1,NKAIN2,ADHFE1,TBCEL,TCF12,SLC44A1,ERCC6L2,RUNDC3B,TTC3,SLC17A7,PDSS2,FAM13C,ST7,FBXO36,ADAMTSL3,NETO2" MicroRNA hsa-miR-1290:PITA hsa-miR-1290:PITA_TOP PITA 1.09E-42 6.12E-39 4.01E-42 3.69E-41 83 353 "GALNT13,PCDH19,OSBPL6,SEMA6A,UNC79,AMPH,LRFN1,ZBTB10,BCL7A,CACNA2D1,CABP7,SPAG9,MAGI1,DLGAP2,SRSF11,FAM19A5,HECTD1,AKAP7,HAPLN1,PLCXD3,FAM131B,YTHDC1,KIF19,CPEB2,SLC12A6,PDCD6IP,FAM78B,MBNL2,RCAN2,CLVS1,ACSL4,C15orf41,MSTN,ARFIP1,GPR34,PSIP1,HAS2,MIER3,MAP2,NFIX,NLGN3,PIK3C2A,LRP12,MINDY2,WBP1L,SNRK,TMEM255A,OXR1,DPF2,PBRM1,KLHDC8A,ROBO1,FBXW7,AP1AR,FNDC3A,PPP4R3A,WDR47,SEPHS1,CCDC88A,BTBD7,ATF7IP,TMCC1,SP2,NKAIN2,STAU1,SYN1,CAMTA1,TCF4,CRTC1,HEY1,LRRC8A,WBP2,FAM155A,ZNF711,ZNF24,CELF4,ZNF189,CADM2,KCNAB1,RGS7BP,FZD3,KAT6A,FRMD6" MicroRNA hsa-miR-1205:mirSVR_highEffct hsa-miR-1205:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-42 6.27E-39 4.10E-42 3.77E-41 120 748 "KCNH8,SYN3,BRAP,KIAA1211,KIAA1324,OSBPL8,CC2D2A,AMPH,ANK2,SUGT1P4-STRA6LP-CCDC180,SLC4A4,DPY19L3,TTLL9,ST3GAL5,ARHGEF7,CACNA1A,CALB2,KALRN,SLC25A14,CAST,RUNX1T1,DGKI,LRBA,LETMD1,CRY2,GDA,KATNAL2,RIPOR2,KCTD8,IST1,DDX46,EXOG,DNAH9,AASDH,KLHL5,YAF2,DCTN4,MFSD10,LRRC17,GPHN,GMPR2,CD320,CLVS1,RACK1,FCGRT,FHL1,SYNCRIP,TMEM107,ATP2C1,ERGIC3,FAM120B,ZNF559,COPS8,MAP7D2,TDRKH,ADAMTS13,CLASRP,TNFAIP8L3,GABARAPL2,DISP2,KCND2,GATD1,IPO5,MAT2A,MBD1,POC1B,MMP16,MYO9A,RTL5,NF1,CNOT4,OXTR,P2RX7,ENPP2,TMIE,RETREG1,FAM216A,RASGEF1B,EPDR1,RELN,KLK6,APTX,TMEM260,TMEM231,RPL15,HSD11B1L,ATAT1,FAM192A,SEMA6D,SATB1,ATXN7,SCN8A,ZFP2,SGK1,HKDC1,SLC6A8,SLC11A1,SLC22A4,ANKRD36,KDM3A,SSPO,STAU1,COBL,SLC37A2,FBXW11,ZFP90,RPGRIP1L,FRYL,AP4E1,PCDH20,ATP6V0E2,ZFAND5,UPF3A,SLC30A4,DNALI1,ADAMTS9,PCBP4,WNK3,UBE3B,FRMD6" MicroRNA hsa-miR-1282:mirSVR_lowEffct hsa-miR-1282:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-42 7.28E-39 4.76E-42 4.38E-41 115 690 "RALGAPA1,KCNH8,SYN3,GALNT13,CC2D2A,DPP10,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARNTL,MARK4,EIF4G3,BCL7A,BMP7,FUBP1,BTK,CA8,SPAG9,RUNX1T1,CCNH,LOC730101,NOG,CNOT8,RAB33A,NRXN3,FHL5,FAM149A,AKAP6,ZNF521,RGS6,DCAF4,HEPH,DMD,DTNA,ECM2,DNAJB6,FAM13A,PHF20L1,SUGP2,DENND4A,GTF2IRD2,FGF12,IP6K2,EFCAB2,PDLIM5,ATP2C1,STAU2,SULT1C4,ZNF276,GLI2,RAB30,PRUNE2,GPR37,GRIA2,GRIK4,GRM8,PSIP1,FAM107A,MAP4K5,ELOVL5,IGFBPL1,CPT1C,CELF5,LRRCC1,SCIN,KCNB1,KCNN3,STMN1,NCOA7,ASPRV1,MAP2,MBD1,MITF,MKLN1,ZNF680,NOVA1,PCDH8,PCDH9,ABCB1,FAM216A,MAPKAP1,STRN3,SH3KBP1,PPP2R5E,MAPK4,CNTLN,PTN,STRC,REV3L,PBRM1,AP1AR,SALL1,SCN8A,SH3GL3,PREX2,SLC11A1,CXXC4,SPP1,NXT2,ZSCAN29,SEPT8,DIP2A,PHLDB1,SYT1,ADGRL3,TBCEL,TCF4,SYNE1,TRIO,TTC3,WIPF1,CLIP2,DHX33,MFF,PDSS2,ACTR3B" MicroRNA hsa-miR-1299:PITA hsa-miR-1299:PITA_TOP PITA 1.41E-42 7.89E-39 5.15E-42 4.74E-41 89 411 "PCDH19,SEMA6A,SPOP,NCOA1,ATP1B3,RNF182,ADAM23,CACNA1I,CA8,DLGAP2,NUMBL,CLCN3,MYRIP,IGDCC3,PUM1,BOC,RHOBTB1,YAF2,MBNL2,TENM1,TNK2,EPB41L2,RASGRP2,ERBB4,NCALD,DLC1,MED12L,AGAP2,SEMA4D,HRASLS5,GATM,MSTN,TCERG1,LUZP2,GPD2,GRB10,PSIP1,ADAMTS6,BACH2,MIER3,NKD1,SLC6A17,KCND2,MARK1,MEIS2,CHAMP1,PDE3A,KCTD15,SDK2,RANBP3L,CEP41,GDPD1,OXR1,GTDC1,RPS6KA2,HUNK,KCNIP1,RYR3,CSRNP3,SH3BGR,CHD9,FAM214B,LMBRD1,FNBP1,ITPRID2,ERBIN,STAU1,ZSCAN29,ZC3H4,PRRC2C,SYN2,ANKRD28,MCF2L,TCF4,CUX2,FRYL,DICER1,ZFPM2,CHST8,TIAM1,ZIC1,NDRG4,SMARCAD1,SLC30A4,CADM2,NAV3,HNRNPA3,MSRB3,FXR1" MicroRNA hsa-miR-518f*:mirSVR_highEffct hsa-miR-518f*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-42 8.27E-39 5.39E-42 4.96E-41 121 762 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,ADGRV1,EYA1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,TMEM260,GAL3ST4,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-526a:mirSVR_highEffct hsa-miR-526a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-42 8.27E-39 5.39E-42 4.96E-41 121 762 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,ADGRV1,EYA1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,TMEM260,GAL3ST4,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-518d-5p:mirSVR_highEffct hsa-miR-518d-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-42 8.27E-39 5.39E-42 4.96E-41 121 762 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,ADGRV1,EYA1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,TMEM260,GAL3ST4,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-520c-5p:mirSVR_highEffct hsa-miR-520c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-42 8.27E-39 5.39E-42 4.96E-41 121 762 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,ADGRV1,EYA1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,TMEM260,GAL3ST4,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-769-3p:mirSVR_highEffct hsa-miR-769-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-42 8.47E-39 5.51E-42 5.07E-41 97 492 "KIAA1211,BEND6,OLMALINC,ADGRF5,AMT,PLA2G4C,CFLAR,ZNF501,CLDN10,KRIT1,SUMF2,FAM171B,ANKRD44,SNCAIP,GPRASP1,ARMCX4,JAKMIP2,ELMO1,EXOG,GRIN3A,DMTF1,FARSB,EDN1,EDN3,FCF1,APH1A,RASA4,GOLGA7,DCTN4,ENO2,RCAN2,SRRM1,F8,TAOK3,FDFT1,KAT8,POLK,GABRG2,B4GALNT1,MAP7D2,FAM19A2,FAM222A,FRMD3,HLF,HNF4G,HNMT,LRRC75A,LRRC25,MEIS2,SRSF12,MEST,MYO7A,VWA2,CNOT4,NOVA1,NPTX1,PCSK5,PCDH18,RASGEF1B,HYDIN,PTPRE,TTC13,OXR1,HKR1,PBRM1,C12orf49,ADAL,SCN8A,SEC14L1,CCDC92,WDR47,KBTBD4,SMARCD3,INTS9,RCOR3,LIMCH1,KDM4C,SPART,POGZ,TACR1,SATB2,RNF175,AP4E1,PIK3R5,CDK20,SYNPO2,TUBB1,UBE2H,VLDLR,WIPF1,ZNF708,MICU3,ZNF154,REEP1,INTS3,STOX2,NHSL1" MicroRNA hsa-miR-3122:mirSVR_highEffct hsa-miR-3122:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-42 8.94E-39 5.81E-42 5.35E-41 106 589 "RALGAPA1,NCKAP5,GALNT13,C1QTNF3,PCDH10,GPRASP2,SUGT1P4-STRA6LP-CCDC180,CACNA1B,CAST,RUNX1T1,NDST3,IQCK,SUMF2,ABI3BP,GDA,PDE4DIP,ALKBH8,WDR20,ACOT8,ARRDC4,TOM1,E2F6,PHC2,YAF2,PHF20L1,SUGP2,GOLGA7,PAN3,VPS13B,NCALD,ARMCX1,FCGR3A,ZNF589,OLFM1,IP6K2,C2orf88,ATP2C1,DISC1,TXNL4A,TNRC6A,ZNF638,MAP7D2,PCLO,FAM19A2,RNF165,FRMD5,HMGCL,NEGR1,NKD1,LAMP2,STMN1,MBD1,NEXMIF,NME4,NOVA1,NPTX1,NTRK2,OXTR,P2RX7,PCDH9,PCSK1,DUSP26,ZNF655,SNX10,GRAMD1C,SAMD9,ANKHD1,PTPRE,TTC13,RFX2,GSTCD,MCMBP,ATP8B4,ABCA11P,PRCD,SUPT20H,SH3GL3,ABTB1,RCOR3,INAVA,CABCOCO1,SNRPN,KDM4C,CDK19,ATP10B,CLSTN2,SULF2,SEPT3,SYN1,TCEA1,TCF12,SYNE1,OBSL1,VWCE,ACTR6,TPM2,METTL3,SMUG1,RUSC1,TUBB2A,LINC00689,VSNL1,ZIC1,EML6,PRTFDC1,SIGLEC10" MicroRNA hsa-miR-151-3p:mirSVR_highEffct hsa-miR-151-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-42 8.94E-39 5.81E-42 5.35E-41 106 589 "KCNH8,XKR4,ADD1,PWWP2A,ZNF608,NME5,TAOK1,SRPX,PCDH10,CHRD,NUMB,ATP2A2,WASF1,CAST,KRIT1,LOC730101,CLTB,SULT4A1,ARMC8,RNF14,RGS6,OSBPL3,SOCS5,SPOCK3,DPYSL2,ABCC5,DNM1L,E2F6,FAM13A,MBNL2,EIF4G2,DCTN4,USPL1,DLC1,SUCO,DLL3,ZMAT1,GABBR1,CHL1,C15orf41,LRRC37A6P,TUBGCP4,GHR,BRD8,GNAO1,GPD2,PCLO,PSIP1,MIER3,LRRC75A,LRRTM1,LIG4,BEX5,GLIPR1L2,PRKACB,VPS13C,ZIK1,OXR1,GTDC1,GSTCD,RPE,SPIN3,RYR3,STUM,TRA2B,HSPA4L,SHC4,SLA,FAM81A,WDR47,KDM4D,CCDC88A,ANKRD36,MBD5,ZNF415,USP33,CLASP2,ERBIN,KLHL4,ZEB1,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,ZFPM2,AP4E1,TIAM1,TPM1,NPL,STXBP4,UCHL1,TBC1D15,ZNF24,TRIM9,SPIRE1,SMARCAD1,URM1,SLC17A7,WNK3,FXR1,NETO2" MicroRNA hsa-miR-2116*:mirSVR_highEffct hsa-miR-2116*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-42 9.41E-39 6.11E-42 5.63E-41 112 657 "ACADM,NDRG2,KLHL32,ELFN2,GALNT13,BEND6,INTS2,MTUS1,NUMB,ATP1B3,ATP2A2,CFLAR,NAE1,MTMR7,MAGI1,PLEKHB1,MYL6B,HECTD1,RCHY1,SEC24C,DZIP3,RUBCN,CYBB,GPRASP1,GAPVD1,ARMCX4,ZNF804A,PLPPR4,DOCK2,DMTF1,EBF1,HIPK3,EGFR,KCTD3,SRRM1,FAM198B,TMEM132C,RACK1,FCGRT,TMEM164,SUCO,PSD2,C2orf88,CELF1,ZMAT1,GABRA3,MTHFD2,DISC1,WASHC2A,ADAM28,GGTA1P,LILRB4,GRB10,GRIA2,ADAMTS13,AP4S1,ADAMTS6,IDH3B,RBPJ,CREG2,KIF5A,STMN1,MARK1,MBNL1,POC1B,AFDN,NEFM,NELL2,NTRK2,OXTR,GPR137C,TREM2,PURG,PRIMPOL,EPB41L4B,DRAM2,PRKACB,DIRAS2,DCHS2,PIGG,STK32A,RASGRF2,KLHL11,ZFHX4,SCN8A,WDR37,ANKRD36,LMBRD1,SOX3,ZNF302,APOM,SEPT8,FAM208A,ADGRL3,SIK3,DICER1-AS1,TIAM1,ERCC6L2,PIK3R5,SMUG1,DCBLD1,RUSC1,RPL7L1,UBE2H,LYPD6,DHX33,MFF,CADM2,VPS35L,FAM47E,PCBP4,JMJD1C" MicroRNA hsa-miR-421:PITA hsa-miR-421:PITA_TOP PITA 1.74E-42 9.73E-39 6.32E-42 5.81E-41 83 355 "KLHL13,OSBPL8,SLC4A4,SEC11C,CACNB4,RUNX1T1,CLDN10,LDB2,ZMYM4,CFL2,FOXN3,QKI,BAG4,CRY2,CS,APPL1,PLCXD3,DOCK4,HDAC4,JAKMIP2,SNAP91,SPOCK3,DYNC1I1,RCAN2,DNAJC27,EYA1,FGF13,MEX3B,FOXO3,FAM49B,PCDH17,PPARGC1A,SPIN1,GNAO1,GPD2,GRB10,FAM19A2,BACH2,IGF1,IPO5,PACRG,SMAD1,MARK1,MEF2C,MEIS2,MITF,NFYA,CNOT4,NPTX1,CLDN11,PDE4B,XRN1,PMP22,STRN3,PPP2R5E,KANSL1,BCAS3,PTPRB,USP47,RDX,RFX3,NUDT11,RORB,PPM1E,PPP4R3A,EPN2,SEPHS1,KBTBD4,CPEB4,SNAP25,TTBK2,ARHGEF9,ANKRD12,CAMTA1,TSN,TUBB2A,FLRT2,ZIC1,TMEM237,POLR3H,CADM2,KAT6A,RNF146" MicroRNA hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA_TOP PITA 1.81E-42 1.01E-38 6.56E-42 6.04E-41 90 422 "CCDC85A,HACE1,OSBPL8,SPARCL1,ARHGAP20,DPP10,USP37,PPP4R4,NUMB,RNF182,CALB2,RUNX1T1,LDB2,ZMYM4,FOXN3,TMEM184B,CNR1,GDA,CLIP3,ERC2,PLCXD3,GAPVD1,SNPH,HDAC4,DAPK1,ZC3H11A,POM121,SGSM2,PHC2,YAF2,FAM13A,ETV1,DLC1,FGF13,UBE2E3,FOXO3,CPLX2,SRCAP,PPARGC1A,TOX3,TNRC6A,STMN2,KAT7,BACH2,NEGR1,SMAP1,ZIC5,STXBP5,MEIS2,AFDN,HS6ST3,ZC3H12B,CNTN3,PDE4D,GPR85,OLA1,PIK3C2A,PURG,EPB41L4B,KANSL1,CEP41,MTMR10,PTPRB,PTPRD,RFX3,ZNF532,CARF,LRRK2,KIF21A,EPN2,SLC8A1,PDZD2,SOX11,RBM26,NKAIN2,PRRC2C,SYNE2,PLCB1,SYPL1,TRIM2,PUM2,SIRT1,TBC1D15,ZIC2,REEP1,ZFAND5,EVI5,HNRNPA3,ACTR3B,RNF146" MicroRNA hsa-miR-1224-5p:mirSVR_highEffct hsa-miR-1224-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-42 1.01E-38 6.56E-42 6.04E-41 113 669 "RALGAPA1,CLK4,ABHD6,NCKAP5,ADORA2A,MAP4K3,UPRT,SEMA4G,MADD,CFLAR,DST,ARHGEF7,GYG2,THSD7A,RUNX1T1,CBR1,KRIT1,DGKI,CFL2,PPT2,TPP1,C4orf33,IQCK,COL11A2,CRYM,PDE4DIP,ERC2,PNPLA8,RIPOR2,AIF1L,KIAA0753,SPOCK3,E2F5,GOLGA7,GORAB,SPSB4,FGF12,NOP56,MEGF11,GALC,LRRC37A6P,SULT1C4,BRD8,GPD2,GSTM5,ZHX1,PACSIN2,GABARAPL2,HMGCL,MSL1,NME9,SLC35G1,CREG2,PIK3AP1,MAP4,MBP,KITLG,MMP16,NOVA1,GPR137C,PFKFB2,NALCN,PRIMPOL,PRKACB,MAPK10,BDNF-AS,PTPRB,PTPRG,TTC13,ZNF493,ZDHHC14,GTDC1,ZDHHC4,EMID1,LRRK2,PTGR2,DGLUCY,SEMA6D,SATB1,FNIP1,SEC31A,ZNF430,RCOR3,INAVA,CLSTN2,KLHL7,NUDT10,KLHL4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,CDH22,TRO,TUBB2A,EIF4ENIF1,UCHL1,ZNF17,ZNF138,ADAMTS9,MDH1B,ITM2C,PLSCR4,FZD3,UBE3B,CASC15,DPF3,RNF146,SENP7" MicroRNA hsa-miR-520f:PITA hsa-miR-520f:PITA_TOP PITA 1.83E-42 1.03E-38 6.64E-42 6.12E-41 93 452 "ABR,MTUS1,HECW2,OSBPL8,AK2,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,CALB1,PRC1,CDC25B,CDH2,CFL2,LETMD1,AKAP5,IGDCC3,ZNF385A,SOCS5,RUBCN,USP6NL,RASSF2,ZNF804A,ZC3H11A,ABCC5,MBNL2,KMT5B,PAN3,EMX2,DNAJC27,EZH1,MED12L,FOXO3,AFF2,MAP7D2,FAM222A,ZHX1,BACH2,IL6ST,SYTL4,MARK1,MBNL1,MEF2C,NOVA1,NPTX1,NRCAM,GPR137C,PCDH9,LRP12,PKIA,TMEM260,PTPRD,RDX,RET,FIGN,SLC25A36,ALG9,FNDC3A,WDR37,FAM214B,TET1,RCOR3,HECW1,ARHGAP26,CDK19,LMO3,RGL1,STXBP1,KLHL7,ARHGEF9,PLCB1,SYT1,ANKRD12,FBXW11,CUX2,ZFPM2,TNS1,NR2C2,TRPS1,TOM1L2,VLDLR,ZNF711,LYPD6,TMEM237,UPF3A,PRDM8,PRDM10,NAV3,FAM13C,ADAMTSL3,MSRB3" MicroRNA hsa-miR-4280:mirSVR_highEffct hsa-miR-4280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-42 1.03E-38 6.69E-42 6.16E-41 107 601 "KCNH8,DPY19L2P4,CC2D2A,C1QTNF3,ALCAM,MAP4K3,SUGT1P4-STRA6LP-CCDC180,BCAS1,ARNTL,ATP2A2,BACH1,ADGRB3,ARHGEF7,C5,SPAG9,PLEKHB1,EPS15L1,CLCN3,SRP14-AS1,AKAP7,FAM149A,AKAP6,SEC31B,CSNK1G3,DZIP3,UBXN2A,PNPLA8,RIMS2,GPRASP1,PITPNC1,JAKMIP2,USP3,DPH1,DTNA,WDPCP,FRY,KMT5B,ARMCX1,SH3YL1,SCML2,GTF2IRD2,POLR1B,FLT1,ANKFY1,SLC37A3,GABBR1,ADGRA3,HMGCL,NEGR1,ITPKB,KCNN2,IPO5,PAXBP1,LRP1B,MEIS1,SRSF12,BLOC1S2,NEK1,NF1,CNOT4,PDE4D,OLA1,LRP12,PRKACB,GRAMD1C,WBP1L,QRICH1,CNTLN,MTMR10,STK32A,EML5,PTPRG,RAP1GDS1,NUDT11,RNASEL,CCDC82,RPE,TCP11L1,FAM161B,COPZ1,SCAF8,CCDC88A,MYO16,HECW1,KDM4C,STAU1,NUDT10,COBL,ADGRL3,TCF12,SIK3,SIRT1,AP4E1,ARL10,MTMR14,NR2E1,PPIL6,ZKSCAN5,HIRA,FAM155A,GORASP1,FLRT2,MKRN3,ANKS1B,HPS4,DOCK8,JPH3" MicroRNA hsa-miR-3144-3p:mirSVR_highEffct hsa-miR-3144-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-42 1.13E-38 7.33E-42 6.75E-41 134 926 "KLHL32,CASKIN1,WDR35,TAOK1,ALCAM,OGT,PKP4,PPP4R4,ARNTL,ZBTB10,INSYN2B,EIF4G3,RUNX1T1,NFS1,LRBA,CFL2,FHL5,AKAP6,AKAP5,ABI3BP,COX4I1,TOGARAM2,MYRIP,ZNF521,GDA,KIAA0040,UBXN2A,RIMS2,HDAC4,SCRN1,MYEF2,SACS,NR1D2,DPP6,PDCD6IP,ARRDC4,GOLT1B,EDN3,FRY,EGFR,GOLGA7,RCAN2,RABEPK,CEP85L,ETV1,EYA1,ACSL4,DLC1,RACK1,FER,FGFR1,STAU2,GAD1,ERAP1,TNRC6A,LOXL3,GPD2,LPAR4,SOX21,NEGR1,SMAP1,KCNJ16,LAMP2,AQP11,MEF2C,CLDN11,P2RY1,GLIPR1L2,NALCN,ING3,PPP2R5E,PRKACB,DCHS2,PEX2,TMEM231,USP47,RAP1GDS1,OXR1,RDX,GTDC1,RGS12,ZFHX4,SETD5,CARF,YY1AP1,ATP8B4,HUNK,NCBP3,TRAPPC13,SALL1,SH3GL3,CPEB3,HKDC1,CNKSR2,NLGN1,DHX30,ATF7IP,MYH15,SNCA,BDP1,DBNDD2,ATP10B,LARP4,SYP,SYPL1,MTCL1,TCEA1,SATB2,SYNE1,NSD1,DICER1-AS1,AP4E1,NPL,SMUG1,RUNDC3B,STXBP4,CLHC1,FLRT2,WIPF1,RICTOR,GUSBP1,PCDH20,TCEAL7,AMZ1,ZFAND5,EMSY,MFF,PRTFDC1,FIP1L1,FAM47E,PARP11,RGS7BP,MRPL47,RNF170" MicroRNA hsa-miR-450a:mirSVR_lowEffct hsa-miR-450a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.49E-42 1.40E-38 9.02E-42 8.31E-41 88 404 "ADD2,AP2A2,C1QTNF3,SUGT1P4-STRA6LP-CCDC180,USP37,GPR146,CACNA1B,LRWD1,ARHGEF6,ABI3BP,ZFP28,OSBPL3,IPCEF1,PHF14,DOCK4,GPRASP1,TBC1D5,MATR3,INTS1,SPOCK3,TMCC2,GRIN3A,RAB39B,DMPK,NR1D2,DPH1,PDCD6IP,OPTN,MBNL2,PLEKHA1,LRRC17,ENPP6,SCML2,MEX3B,IP6K2,PSD2,PDLIM5,PRELID3A,GABRA3,ERAP1,DISC1,ZNF276,STMN2,GRIA2,GRM8,CIT,MAP4K5,ATOH8,KIAA1755,IPO5,GPR155,MEIS2,AFF1,SAMD5,ADAM22,NEK1,SLC25A23,EXOSC10,ING3,TATDN3,RASGEF1B,TMEM260,MARCH1,PID1,IQSEC3,NUDT11,GSTCD,ZC3H14,MEG3,ST6GALNAC6,ATXN2,FNDC3A,KANSL3,SLC22A4,ANKFN1,BDP1,ATP10B,CEP68,HIF3A,AP4E1,C9orf85,FAM155A,UBTF,VLDLR,RBFOX3,ZBTB38,FZD3,ACTR3B" MicroRNA hsa-miR-650:mirSVR_highEffct hsa-miR-650:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.55E-42 1.43E-38 9.21E-42 8.48E-41 118 730 "XKR4,ADORA2A,KIAA1324,PCDH10,FAM135A,TNRC6C,ARHGDIA,NCOA1,CHID1,EIF4G3,KIF1A,SYNJ1,RUNX1T1,USP2,P2RX6,DLGAP1,CFL2,CHN2,CPNE6,FBXO7,QKI,SUMF2,LETMD1,GAL3ST1,FAM171B,ANKRD44,CS,CSNK1G3,VCAN,DZIP3,ARHGAP32,GAPVD1,DGKB,PABPC5,ZC3H11A,EXOG,RPS6KL1,CASP8AP2,DPP6,ACOT8,DTNA,E2F6,EDN1,PHF20L1,EBI3,ING4,SRRM1,SIRPB1,FAM198B,DLC1,FCGR1A,SUCO,PSD2,HRASLS5,FAM120B,B4GALNT1,INPP5K,PCLO,GRIN2D,FAM19A2,TOX2,ICA1,ZIC5,KCND2,MITF,MXI1,MYO9A,SFR1,NF1,NTRK3,PCSK5,CDK18,PDE1B,NALCN,CCSER2,PLCL1,PMP22,GRAMD1C,HYDIN,DCHS2,RELN,PTPRE,ZNF493,RASGRF2,NUDT11,C12orf49,ARMC5,ROBO1,KCNIP1,RYR3,AP1AR,SCP2,DZIP1,IFT122,ZC3H13,DBNDD2,ZSCAN29,NUDT10,DNAJC9,TBCEL,FBXW11,USP32P1,DICER1-AS1,AP4E1,SLC44A1,TIAM1,HEY1,R3HDM1,ZNF346,RUNDC3B,KCNE5,MTCH1,ZNF177,ADAMTS9,ST7,CASC15,JMJD1C,NLRP3" MicroRNA hsa-miR-4305:mirSVR_highEffct hsa-miR-4305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-42 1.61E-38 1.04E-41 9.57E-41 98 506 "SYS1,CCDC85A,PTCHD1,ZNF578,LRFN1,TTLL9,ADGRB3,CALB1,LRBA,MAGI1,CFL2,SRSF11,AKAP6,CLOCK,ENTPD4,CRMP1,PDE4DIP,PHACTR3,GAPVD1,GSDME,RHOBTB1,DMTF1,ACOT8,SEMA3D,FSD1L,FAM13A,EIF1,SEC23B,FOXF2,PSD2,EFCAB2,POMT1,ZNF44,ZNF559,ACSS1,FREM1,CBX1,FERMT2,RASSF8,ZHX1,ICA1,FAM95B1,JAK2,KCND2,KIT,MARK1,MBD1,MBNL1,AFDN,NEK1,CNOT4,OCRL,PDE4D,MTRF1L,ING3,IRX1,PTPRG,PID1,RAP1GDS1,RASGRF2,FIGN,NUDT11,CCDC82,EXD2,ROBO1,ATAT1,GALNT10,CPEB3,EPN2,ZKSCAN3,ZFP1,DMRTC1,LIMCH1,PDZRN3,UNC5B,NUDT10,TCF4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ITGB3BP,BHLHB9,WIPF1,XPO1,ZNF711,MICU3,KCNT2,TMEM237,EMSY,FAM13C,UBE3B,KLHDC1,RNF146" MicroRNA hsa-miR-330-5p:mirSVR_highEffct hsa-miR-330-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.96E-42 1.65E-38 1.07E-41 9.83E-41 119 743 "RALGAPA1,DGCR6,EMILIN3,SYS1,PLEKHH1,ADORA2A,RNF150,CASKIN1,FAM135A,DOC2A,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,PKP4,TMEM108,ALDH7A1,N4BP2L1,ATP6V1G2,BARD1,SEC11C,RGS9,NRP2,KSR1,RCBTB2,AKAP6,GDA,CSF2RA,LRIG1,OSBPL3,APPL1,GIT2,HEPH,USP3,MED12,DTNB,ABCC5,DNM1L,EBF1,EDNRB,ASB3,C3orf18,SRRM1,ERBB2,CEP78,PPP1R1B,FGF1,FGF11,FGFR1,ANKFY1,MSANTD4,TPPP3,ZNF274,DISC1,IGSF5,WASHC2A,USP19,GGT7,HPGDS,ZNF638,GPD2,BTN2A1,ZBTB49,ATXN2L,IDH3B,ZNF181,LRRTM1,KIF5A,MAT2A,MEST,MYO7A,VWA2,SLC11A2,PALM,PLEC,PLTP,PURG,SCHIP1,SEPT4,PKIA,CNTLN,BDNF-AS,C1orf109,NKAIN1,SLC25A48,OXR1,EXD2,RORB,TNFRSF19,ZFP2,SEC14L1,SH3GL3,FNDC3A,FAM81A,BTBD7,SLC22A4,ZFP1,SNRPN,ZSWIM8,SSPO,ERBIN,STAU1,ZSCAN29,ELOVL4,ARC,TCF12,RNF216P1,ITGB3BP,CDH22,ENHO,CDK20,UBE2H,UGT8,MTCH1,VLDLR,ELFN1,ZNF189,DHX33,PPP1R3F,SMIM8,CASC15" MicroRNA "ATTCTTT,MIR-186:MSigDB" "ATTCTTT,MIR-186:MSigDB" MSigDB 2.98E-42 1.67E-38 1.08E-41 9.90E-41 71 253 "CLK4,ZNF608,OSBPL8,LRCH2,PARG,CALB1,CAST,LRBA,SEPT7,QKI,ZNF385A,CNTNAP2,ZC3H11A,PLPPR4,SNAP91,GRIN3A,CPEB2,MBNL2,TMEM35A,PAN3,EPHB1,ACSL4,DLC1,MEX3B,CELF1,FICD,ZHX1,BACH2,HNMT,NEGR1,INSM1,KCND2,MAP2,MAP4,MBNL1,MITF,MYT1,IGSF11,P2RX7,GPR85,PFKFB4,MAPKAP1,PPM1B,GTDC1,ZFHX4,SALL1,SMPD3,RASA3,SCAF8,CPEB3,FNDC3A,BTBD3,EPN2,TRIM67,CPEB4,SOX11,SP4,NECAB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DOK6,TRPS1,UBE3A,PRDM10,WNK3,JPH3" MicroRNA hsa-miR-575:mirSVR_highEffct hsa-miR-575:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.64E-42 2.60E-38 1.67E-41 1.54E-40 114 687 "PWWP2A,KLHL13,SPOP,PHF12,PKP4,EPB41L5,MADD,CHRD,TTLL9,DST,SYNJ1,PTBP2,SPAG9,CBLN1,MTMR7,CBFA2T2,AP4M1,DCLK1,MAGI1,CFL2,CNOT8,LETMD1,COL9A3,RNF14,CSNK1G3,SLITRK5,GAPVD1,DAPK3,DBN1,DDX46,SNAP91,SACS,HS3ST2,GOLT1B,EDN3,PHF20L1,EGFR,EIF1,EPHB1,IGSF6,DLC1,RACK1,MED12L,POLK,SEC23B,NELFCD,CINP,AP4B1,GABBR1,KIAA1841,IGSF5,GCNT2,TUBA8,DBF4,PCLO,ATP2B1-AS1,GRIA2,GABARAPL2,CELF5,KCND2,KCNQ3,CREG2,CAMK2N2,HECTD2,ZFYVE27,AQP11,MBD1,MEF2C,ZNF680,NFE2L2,PDE1C,MAPKAP1,SEPT4,PPARA,LRRN3,MAPK9,GRAMD1C,HYDIN,BDNF-AS,FAT4,RDX,RFX3,RGS12,GSTCD,ELP2,NEK11,EPHA10,LRFN5,PRCD,FOXRED1,SCAF8,CHD9,FAM81A,ZKSCAN3,ZFP1,ZNF667,LMBRD1,ZSWIM8,ZC3H13,MTCL1,FBXW11,PUM2,FRYL,TTTY15,UGT8,ZNF708,TMEM237,EML6,MEIS3,CADM2,WNK3,PARP11,FAM13C,ACTR3B" MicroRNA hsa-miR-122:mirSVR_highEffct hsa-miR-122:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.80E-42 2.69E-38 1.73E-41 1.60E-40 107 607 "ACTN1,KLHL32,GALNT13,AMPH,UPRT,INSYN2B,DPY19L3,ADGRB2,CFLAR,C5,HIP1R,CBR1,C1orf52,NUMBL,PLEKHB1,SEC31B,CRMP1,CLIP3,CS,DOCK4,HDAC9,IST1,SPOCK2,DMD,DTNB,ABCC5,FAM13A,PHF20L1,TENM1,SIRPB1,F8,CLVS1,RPS6KC1,GTF2IRD2,NOP56,GABBR1,GABRA3,GAD1,FAM120B,GALC,SYT17,IGSF5,MMADHC,TNRC6A,MSL3,LUZP2,DCLK2,GPD2,GRIA2,IL6ST,FAM69A,KCNJ16,MEIS2,MYCN,MYO9A,NEK1,SLC11A2,NTRK2,OCRL,GPR137C,ZNF827,PDCD2,GPR173,ZDHHC8,CCSER2,PKM,MASP1,CNNM2,PTPRB,RASGRF2,TMLHE,CYB561D1,CCDC102B,AP1AR,TNFRSF19,SUPT20H,FNDC3A,FHOD3,SLC4A3,SLC6A11,SMARCC2,LIMCH1,ZNF415,SSTR1,SS18,STAU1,RGL1,KANK1,NUDT10,SIRT1,TLR4,PRRT1,SYNPO2,SMUG1,STXBP4,UGT8,OSBP2,MICU3,LYPD6,SMARCAD1,MAP3K12,PRTFDC1,SLC17A7,PHTF2,JMJD1C,KLHDC1,CPNE4" MicroRNA hsa-miR-646:PITA hsa-miR-646:PITA_TOP PITA 5.00E-42 2.80E-38 1.80E-41 1.66E-40 91 437 "RALGAPA1,ASIC1,ADRA1B,KLHL13,TAOK1,BIN1,CDC14B,JAZF1,CAMK2A,DCLK1,NRXN3,HECTD1,AKAP6,AHCTF1,ARHGEF10,USP6NL,GAPVD1,IST1,MFAP3L,ZC3H11A,ARRDC4,FRY,PAN3,RCAN2,TAOK3,DLC1,FLNC,AFF2,SYT3,NBEA,TPPP3,GABRG2,PPARGC1A,MIER3,ELOVL5,ACOT7,SMAP1,NKD1,ZIC5,KCND1,KIF2A,KIF5A,PACRG,MAP2,MAPT,KITLG,MOV10,RTL5,NEXMIF,NOVA1,OCRL,PDPK1,GNG2,PIK3R1,MAPK4,ZFHX4,SETD5,ROBO2,RYR3,PRCD,KIF16B,AMBRA1,CHD9,FNDC3A,CPEB4,TMCC1,FAM126B,ZSWIM8,ZBTB43,CLASP2,RGL1,KANK1,PRRC2C,MTCL1,CAMTA1,SMG6,WSCD1,SATB2,NACC2,NR2E1,ERCC6L2,TNS1,KCNE5,WIPF1,PCDH20,TMEM237,CADM2,GAL3ST3,RTN4,FXR1,GAN" MicroRNA hsa-miR-1204:mirSVR_lowEffct hsa-miR-1204:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.10E-42 2.85E-38 1.84E-41 1.69E-40 104 574 "UNC5A,CC2D2A,CDC42BPA,DPP10,ANK2,FGD2,APBA2,UPRT,PHYHD1,PPFIA3,CDK10,TTLL9,ARHGEF7,SLC16A4,MAGI1,LY86,SLC4A8,MYRIP,ENTPD4,HDAC4,INTS1,DBI,ARMCX4,RUSC2,DDX46,RHOBTB1,USP3,SLC29A4,DPP6,EDN3,SUGP2,EPB41,CD320,TMEM132C,TUBB3,KAT8,WDR83,GATM,ALDH1L1,CRCP,STARD3,KCNMB4,DIDO1,ADAMTS13,PACSIN2,HMGCL,ICA1,KNDC1,CAMK2N2,SFXN5,MAP2,MAP6,MYT1,HNRNPM,VWA2,TBC1D25,CDK18,PDPK1,DUSP26,NALCN,SEMA5B,PLIN1,NECAB2,FSD1,PCDHB17P,LRRN3,PIGG,ZNF615,RAD51D,DPF2,GTDC1,ZDHHC4,RORB,NEK11,HSD11B1L,KCNIP3,DHX30,SEPHS1,SLC14A1,NAPB,MAPKBP1,TSPYL2,DDN,ST5,STAU1,SEPT3,KLHL7,SYNE2,SYP,ALG1,WSCD1,TPCN2,DOCK9,SLC19A3,FRYL,PMS2CL,SYNPO2,BCL2L13,CCDC136,CCDC14,ZNF70,NDRG4,HPS4,SIGLEC10" MicroRNA hsa-miR-378c:mirSVR_highEffct hsa-miR-378c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.94E-42 3.32E-38 2.14E-41 1.97E-40 139 1000 "CC2D2A,ARHGAP20,FAM135A,OGT,DDO,TNRC6C,PLA2G4C,EIF4G3,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,TIGD7,COPB2,PPT2,C4orf33,SRP14-AS1,LY86,RAB26,AKAP7,AHCTF1,TOGARAM2,ZFP28,CDC42BPB,CREM,RNF14,CS,ARHGEF10,PHF14,USP6NL,CCDC144A,DOCK4,RIPOR2,DCAF8,DDX46,GRIN3A,DOCK2,DNM1L,EBF1,WDPCP,HIPK3,CELSR3,MBNL2,KMT5B,ENPP6,SPEG,FAM198B,FCGR1A,CEP78,FCGR3A,FGF12,TMEM164,ATP5PD,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRG2,ERAP1,C15orf41,DISC1,GPT2,TDRKH,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,MAN1B1,SMAP1,IDH3B,MYLK2,IL6ST,KIF2A,MAP6,MARK1,MEST,LYRM9,NCAM2,NDP,NEK1,NF1,NFE2L2,NUCB2,IGSF11,CHAMP1,LOC100128398,ETFRF1,TRHDE,PPP3CA,PRKACB,PRPSAP2,DCHS2,SNRK,PTPRD,USP47,FIGN,RGS4,CARF,ELP2,FBXW7,BAALC,KCNIP1,SEMA6D,ATF7IP,MBD5,IQSEC2,NXT2,NEK4,DIP2A,PLCB1,COBL,TACR1,CAMTA1,AGTPBP1,DMXL2,FRYL,ZFPM2,AP4E1,ZNF106,PPIL6,GUSBP1,TRIM9,CELF4,EML6,ZNF189,UPF3A,CADM2,PRTFDC1,FIP1L1,PDSS2,EPM2A,ST7" MicroRNA hsa-miR-654-3p:mirSVR_highEffct hsa-miR-654-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.46E-42 3.62E-38 2.32E-41 2.14E-40 132 910 "ACADM,NCKAP5,BRAP,KIAA1211,PTCHD1,BEND6,ZNF608,CC2D2A,TAOK1,ALCAM,ABCD2,PHF12,CDK10,ATP1B3,NRP2,SYNJ1,JAZF1,CACNA1I,IL33,CACNB4,CAST,MTMR7,DGKI,CLGN,COPB2,B4GALT6,FAM189A2,COL4A5,SLC4A8,CLIP3,ABCG1,UBXN2A,RIMS2,HDAC9,ARHGAP24,ZNF337,ELMO1,GRIN3A,DMTF1,PDCD6IP,FAM13A,EGR3,TMEM35A,STARD3NL,EIF1,ETV1,CLVS1,ZNF461,FCGR1A,FGFR1,FLT1,KHDRBS3,NSG1,DISC1,SULT1C4,PPARGC1A,RAB30,MSL3,ZNF638,GPD2,PCLO,FAM19A2,BVES,ADAMTS6,MYLK2,ZNF546,ZIC5,SCIN,FAM69A,ITGAM,LAMP2,LSS,MAN2A2,MSR1,ZNF92,NEFM,NUCB2,JAKMIP1,PCDH18,MAPKAP1,ING3,PPP3CA,GRAMD1C,HYDIN,CNNM2,QRICH1,PTPN13,ZNF615,CEP97,TMLHE,ABCA11P,SCN8A,SCP2,CPEB3,SLC6A8,ZNF430,SEPHS1,CPEB4,IFT122,BDP1,PBLD,SSTR2,FAM208A,ALG1,ADGRL3,TBL1X,SATB2,ZEB1,PUM2,FAM200B,ITGB3BP,TMPO,TRIO,KCNE5,TSC2,SSBP2,FAM155A,UBE2H,OSBP2,RICTOR,ZNF708,CADM2,EVI5,HPS4,SIGLEC10,FIP1L1,MPPE1,PARP11,FXR1,NETO2,NETO1,FAM198A" MicroRNA hsa-let-7a:mirSVR_highEffct hsa-let-7a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.13E-42 3.99E-38 2.56E-41 2.36E-40 123 798 "KLHL32,BRAP,ADRB2,RTL9,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CH25H,CHN2,TAOK2,NDST3,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DMD,CPEB2,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,FUT10,CNTRL,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,FAM69A,NME9,KIF2A,MEIS2,CNOT4,NOVA1,OGG1,FAM218A,XRN1,PKIA,GDPD1,MASP1,VPS13C,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,MEG3,ATXN7,FNIP1,KIF27,FNDC3A,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCEA1,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,RICTOR,LYPD6,SMARCAD1,STOX2,PHTF2,GAN" MicroRNA hsa-miR-98:mirSVR_highEffct hsa-miR-98:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.81E-42 4.37E-38 2.81E-41 2.58E-40 124 811 "KLHL32,BRAP,ADRB2,RTL9,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,SLC4A4,ZNF583,BACH1,GYG2,CHN2,TAOK2,NDST3,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,ZNF385A,CREM,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DMD,CPEB2,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,CNTRL,GRIA2,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,ZNF678,NME9,MEIS2,CNOT4,NOVA1,OGG1,FAM218A,XRN1,EPB41L4B,PKIA,GDPD1,MASP1,PTK2,SPDL1,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,ST6GALNAC6,SEMA6D,ATXN7,FNIP1,KIF27,FNDC3A,HECW1,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCEA1,CDH22,MTMR14,LRRC8A,FAM124A,TPM2,PDSS1,UBE3A,RICTOR,LYPD6,ZSCAN26,SMARCAD1,STOX2,WNK3,PHTF2,GAN" MicroRNA hsa-miR-221:PITA hsa-miR-221:PITA_TOP PITA 8.13E-42 4.55E-38 2.92E-41 2.69E-40 73 273 "RALGAPA1,AXIN2,PTCHD1,LRFN2,PITPNM2,APAF1,ATP1A1,BCHE,KSR1,CNR1,ZNF385A,RGS6,SEC24C,RIMS4,USP6NL,ZFYVE16,SPATA2,MYEF2,CDON,ARRDC4,EMX2,ERBB4,SEC24B,SMC2,PPARGC1A,FERMT2,PRRC2B,GRB10,ADAMTS6,ZHX1,MIER3,AGFG1,INSM1,KIT,STMN1,MARK1,MAT2A,ADAM11,MEIS1,NEFH,NOVA1,KSR2,PCSK1,PIK3R1,PDZRN4,PPP2R5E,KANSL1,MAPK10,KHDRBS2,SLC25A36,SEMA6D,KIF16B,CPEB3,FNDC3A,WDR37,WDR47,CCDC88A,TMCC1,CDK19,POGZ,CAMTA1,CUX2,TRIM2,TCF12,DICER1,SIRT1,ZFPM2,TIAM1,TRPS1,SLC35A4,TUBA1A,HNRNPA3,SOCS4" MicroRNA hsa-miR-1912:mirSVR_highEffct hsa-miR-1912:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.93E-42 5.00E-38 3.20E-41 2.95E-40 119 751 "XKR4,NDRG3,FMNL2,GALNT16,KCTD16,OSBPL6,TXNDC16,DPP10,DDO,BCAS1,LGR5,ADAM23,ST3GAL5,KALRN,CAST,NFS1,CBLN1,SEPT7,B4GALT6,NRXN3,PLAA,IQCK,ABI3BP,COX4I1,RBM39,RNF14,LYPD1,GSDME,EXOG,DMD,DNAH9,DYNC1I1,CPEB2,DMTF1,DTNB,GOLT1B,PHF20L1,KMT5B,EIF1,EPHB1,F5,ABCA8,RACK1,ZSCAN30,FDFT1,ATP13A4,ATP2C1,MEGF10,TCERG1,SPIN1,KCNMB4,ADGRA3,GABARAPL2,TCEAL6,EID2B,NKD1,KCNN3,NCOA7,MATN2,MEF2C,MEIS1,OCRL,OGG1,PCSK1,PCSK5,PDCD2,NLGN3,PLIN1,SCHIP1,PPM1B,LRRN3,APTX,SNRK,SPDL1,PTPRG,USP47,ENOX1,RET,FIGN,MRPS18A,SLC25A36,SETD5,GSTCD,RPL15,TCP11L1,SCN8A,PRCD,PEAR1,HKDC1,FHOD3,R3HDM2,SYBU,KANSL3,PKNOX2,SLC12A2,TET1,KIF13A,CMTR2,UHRF1BP1L,KDM4C,CLSTN2,PLCB1,SATB2,ZEB1,RPGRIP1L,SYNE1,PCDHB7,ITGB3BP,ARL10,BHLHB9,ERCC6L2,TRIO,WRN,CLDND1,ZBTB14,PRDM10,NAV3,KAT6A,JPH3" MicroRNA hsa-let-7g:mirSVR_highEffct hsa-let-7g:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.29E-42 5.20E-38 3.33E-41 3.07E-40 123 800 "KLHL32,BRAP,ADRB2,RTL9,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CHN2,NDST3,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DMD,CPEB2,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,CNTRL,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,FAM69A,NME9,KIF2A,MEIS2,CNOT4,NOVA1,OGG1,FAM218A,XRN1,EPB41L4B,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS12,LGI2,SETD5,EXD2,C12orf49,ROBO1,ATP8B4,CLIP1,ATXN7,FNIP1,KIF27,FNDC3A,TET1,HECW1,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,ZNF781,RICTOR,LYPD6,ZSCAN26,SMARCAD1,STOX2,WNK3,RTN4,PHTF2,GAN" MicroRNA hsa-miR-20a-5p:Functional MTI Functional MTI miRTarbase 9.93E-42 5.56E-38 3.56E-41 3.27E-40 144 1071 "FMNL2,ADD1,FZD9,SORCS2,ZNF578,SEMA7A,ATP1B3,BACH1,LDHD,ARHGEF7,MTMR3,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,NCOR2,SOCS5,UBXN2A,DCAF8,DAPK3,DNAL1,YTHDC1,ELMSAN1,FBXL5,SACS,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,KMT5B,EIF4G2,IRAK4,CERCAM,ETV1,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,DLC1,GTF2IRD2,POLR1B,SUCO,ANKFY1,TPK1,SARAF,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,FUT10,CIT,FICD,HAS2,ITPKB,KCNB1,KIT,CAMK2N2,GPR155,CHIC1,SCAMP5,AFF1,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,CCSER2,PKD1,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,PTPRO,CEP97,OXR1,ZNF532,ATAT1,ZNF331,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,KDM4D,BTBD7,CMTR2,FAM126B,SP2,SP4,CDK19,POGZ,STAC2,PRRC2C,ANKRD12,CAMTA1,ADGRL3,TCEA1,TCF4,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,PARD3,RGMB,NR2C2,UBC,TBC1D15,ZNF70,LYPD6,INTS3,MAP3K12,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-let-7c:PITA hsa-let-7c:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-miR-98:PITA hsa-miR-98:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7f:PITA hsa-let-7f:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7d:PITA hsa-let-7d:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7e:PITA hsa-let-7e:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7i:PITA hsa-let-7i:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7a:PITA hsa-let-7a:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7g:PITA hsa-let-7g:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-let-7b:PITA hsa-let-7b:PITA_TOP PITA 1.21E-41 6.79E-38 4.32E-41 3.98E-40 84 373 "PLEKHH1,UNC5A,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ZNF583,USP6,MAP4K4,PCYT1B,AKAP6,AHCTF1,IGDCC3,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,DMD,CPEB2,DPH1,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,TMEM121B,CNTRL,CACFD1,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,CHIC1,NOVA1,PRTG,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,FNIP1,FNDC3A,WDR37,FAM214B,TRIM67,DDN,CLASP2,ELOVL4,ANKRD28,KIAA0930,TSC1,SMARCAD1,MEIS3,SOCS4,GAN" MicroRNA hsa-miR-151-5p:mirSVR_lowEffct hsa-miR-151-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-41 7.66E-38 4.87E-41 4.49E-40 108 625 "AP2A2,TBC1D14,C1QTNF1,SEMA6A,UNC79,AMPH,LRFN1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,CADPS,LINC00173,CARMIL3,GPR146,KSR1,CALB2,P2RX6,ENTPD6,EVI5L,TIGD7,ASIC3,TAOK2,EPS15L1,NRXN3,PPT2,SMARCAL1,CS,CSF2RA,ZSCAN23,ARMCX4,ELMO1,DNM1,HS3ST2,USP3,DNM1L,EDNRA,EGFR,C3orf18,ZNF589,RASL10A,ERGIC3,KHDRBS3,ZNF559,IGSF5,SULT1C4,CYP46A1,MMADHC,STARD3,TDRKH,GRIA2,ADAMTS13,SERP2,GRIN2D,ZNF496,KAT7,FRMD5,HLF,MYLK2,ZNF678,INPP5B,TAGLN3,RTL5,DNHD1,NTRK2,ZNF827,CDK18,ZNF655,ING3,SEPT4,FA2H,SH3KBP1,MAPK4,MAPK10,PRPSAP2,GDPD2,PIGG,PTCH1,PTPRD,PTPRE,GTDC1,RFX2,ZNF532,ROBO2,STK32B,RYR3,SARS,LRFN5,MRAS,SLC11A1,SLC22A4,SMARCA4,CDK5RAP2,NMNAT2,CAMTA2,ITPRID2,TAL1,RPGRIP1L,DOCK9,FRYL,AP4E1,TRPM2,KCNE5,TSC1,TUBB2A,LAT2,ELFN1,EMSY,DNALI1,TRAM2-AS1" MicroRNA hsa-miR-190a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-41 9.05E-38 5.76E-41 5.30E-40 110 649 "ABCF1,ADD2,ZNF608,HACE1,TAOK1,PCDH10,MARCH3,BACH1,FUBP1,CA12,THSD7A,RUNX1T1,CBR1,TBRG4,CFL2,B4GALT6,C4orf33,QKI,TBPL1,ANKRD44,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,DBT,PITPNC1,SPATA2,SV2B,CDON,CPEB2,YAF2,MBNL2,PLEKHA1,CERCAM,TUBD1,RCAN2,ACSL4,FER,TMEM164,TRMO,ZBED3,MPP6,GABRG1,GCK,MMADHC,PPARGC1A,COPS8,KCNMB4,TPPP,BVES,INSYN1,BACH2,USP51,NEGR1,HSF2,IGF1,ZIC5,SCIN,IL6ST,KCNB1,KLHL23,KCNN3,L1CAM,SMAD9,MMP16,NEXMIF,NCAM2,NELL2,NTRK3,PIK3R1,XRN1,PURG,PPP1R1A,PPP2R5E,SNRK,PTPRD,CEP97,SH3TC2,PRIMA1,RIC8B,CARF,FBXW7,AP1AR,CSRNP3,SLC6A8,SLC8A1,SLC12A2,ZHX3,ERC1,STAU1,PRRC2C,SYP,TRIM2,SIK3,ZMAT3,CSMD1,NR2C2,OSBP2,KCNK12,SMARCAD1,SLC30A4,MAP3K12,ZXDA,EVI5,STOX2,ADAMTS9,FAM182B,KAT6A" MicroRNA hsa-miR-512-5p:mirSVR_highEffct hsa-miR-512-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-41 9.76E-38 6.20E-41 5.71E-40 109 638 "PLEKHH1,AP2A2,TAOK1,GPRASP2,INSYN2B,N4BP2L1,ZNF599,DST,CALM1,PTBP2,CAMK2B,SLC25A14,SPAG9,RCBTB2,CNOT8,PLAA,FAM149A,ZFP28,GDA,VCAN,ERC2,ZSCAN23,CENPL,DBI,HEPH,B3GAT3,KIAA0753,SNAP91,WDR20,DNAJB6,E2F6,SEMA3D,EGFR,KMT5B,TUBD1,MFSD10,F8,FCGR3A,OLFM1,MEX3B,SYNCRIP,UFM1,CELF1,GALC,LRRC37A6P,DBF4,TOX3,TNRC6A,ZNF638,CNTRL,HNF4G,HP,RBPJ,ITGAM,METTL21A,KCND2,IPO5,LAMP2,BLOC1S2,NELL2,NTRK2,PCSK1,TRHDE,MAPKAP1,PPM1B,PPP2R5E,MAPK9,VPS13C,STK32A,QDPR,PID1,CEP97,FAM66C,RADX,PBRM1,SETD5,ROBO2,MAP6D1,TRAPPC13,COPZ1,SH3GL3,CHD9,IFT122,RBM34,DIP2A,SYNE2,AGTPBP1,FBXW11,DMXL2,SLC19A3,HIF3A,ZFPM2,AP4E1,ASXL3,ERCC6L2,SYNPO2,TSC1,HSPBP1,FAM155A,USP1,XPO1,EMSY,NAV3,FIP1L1,PDSS2,ST7,PHTF2,ADAMTSL3,TIGD6" MicroRNA hsa-miR-3127:mirSVR_highEffct hsa-miR-3127:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-41 1.00E-37 6.36E-41 5.85E-40 117 732 "CLK4,METAP1D,ADRA1D,LRFN2,AGT,RTL9,OSBPL1A,GPRASP2,LGR5,CDC14B,IGDCC4,ALDH7A1,NAE1,CACNA1B,CACNB4,KALRN,RUNX1T1,NFS1,RAB33A,CRYM,SNCAIP,SEC24C,SUSD5,RIMS2,GPRASP1,DBI,LYPD1,ZC3H11A,ECM2,DNM1L,PHC2,EIF4G2,PLEKHA1,PCOLCE2,PAN3,ERBB2,CLVS1,FAM198B,GORAB,FER,UBE2E3,ANKFY1,NOP56,PDLIM5,TPK1,CELF1,CGREF1,MEGF11,GABRG2,C15orf41,GCNT2,BRD8,ZNF638,GPD2,GRM2,CIT,RNF165,IL6ST,KIT,NCOA7,MAT2A,TM6SF1,MSI1,MSR1,MYO7A,NINJ2,NNAT,PDCD2,PDE4D,GNG2,NLE1,EPB41L4B,PPP2R5E,CNNM2,ZSCAN32,ZIK1,ACSM5,ZSCAN2,MARCH1,NWD1,MSANTD2,ERI2,RFX2,RGS3,RGS12,SLC25A36,GSTCD,TNFRSF19,COPZ1,KIF21A,ASAP3,SHMT2,ABTB1,RCOR3,INAVA,LIMCH1,CABCOCO1,USP33,FNBP1,SYN1,TACC1,FAM208A,ADGRL3,ZEB1,RNF216P1,SIRT1,SLC44A1,HEY1,LRRC8A,RIMBP2,NPL,SYNPO2,ZNF154,LINC02210,FAM13C,FBXO36,CPNE4" MicroRNA hsa-miR-603:PITA hsa-miR-603:PITA_TOP PITA 2.06E-41 1.16E-37 7.33E-41 6.75E-40 85 385 "UNC5A,PTCHD1,DOC2A,OGT,MARCH3,ATP1B3,JAZF1,CALM1,CDH2,CACNA2D2,FOXN3,SOCS6,HECTD1,CNR1,AHCTF1,RBM39,CSNK1G3,MATR3,YTHDC1,SGSM2,DPYSL2,MAMLD1,FSD1L,EGR3,GOLGA7,TMEM35A,PAN3,SYNCRIP,ANKFY1,MEGF10,GABRB3,PCDH17,PPARGC1A,GPR34,PSIP1,ADAMTS6,BACH2,HLF,ZIC5,CAMK2N2,MEF2C,AFDN,GIT1,SLC11A2,GPR137C,PTPRD,PTPRN,TMEM255A,FIGN,RGS4,ZFHX4,PCMTD2,FBXW7,SATB1,NLGN1,SEC31A,CPEB4,TMCC1,SOX11,SP4,PEG10,LARP4,NKAIN2,ERBIN,STAU1,ELOVL4,PLCB1,SYN2,TACC1,AGTPBP1,FBXW11,TCF4,SATB2,TCF12,AP4E1,CSMD1,TRPS1,TSC1,EIF4ENIF1,FLRT2,ZBTB14,TMEM198,HNRNPA3,NETO2,RNF146" MicroRNA hsa-miR-588:mirSVR_highEffct hsa-miR-588:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.20E-41 1.23E-37 7.81E-41 7.19E-40 113 686 "KCNH8,KLHL32,PWWP2A,PTCHD1,HACE1,ALCAM,ABCD2,ARHGAP20,FGD2,MAP4K3,PHYHD1,IGDCC4,RGS20,ZNF582,BACH1,ADGRB3,RGS9,DST,BTK,CA12,COL4A5,ABI3BP,COX4I1,TRIM69,CCDC144A,CYBB,RIPOR2,LONRF1,DGKG,ZC3H11A,RHOBTB1,AASDH,EDNRA,EDNRB,FCF1,OPTN,FAM13A,PLEKHA1,TMEM35A,DCTN4,EMX2,ZNF549,ABCA8,RACK1,FCGR1B,GORAB,FHL1,OGA,FYN,GALNT15,GAD1,DISC1,TUBGCP4,GHR,DCLK2,TDRKH,ZNF496,CLASRP,FAM107A,ADAMTS6,CFAP126,ZNF546,KCND2,LMO2,MAP2,MARK1,RTL5,DNHD1,SLC11A2,P2RX7,GPR137C,PCDH9,NALCN,TMIE,NLE1,PLIN1,ING3,APTX,TMEM260,PTPRO,ACSM5,CCDC82,ROBO1,FBXW7,SEMA6D,SCN7A,CCDC92,SEPHS1,SLC12A2,ELMO2,MYH15,SPATA7,MYCBP2,IQSEC2,CLSTN2,POGZ,SULF2,KLHL7,SLC37A2,TACR1,DMXL2,SLC44A1,ERCC6L2,RUNDC3B,TRO,UBE2H,GUSBP1,ZFP37,ZNF24,MDH1B,SLC17A7,KCNAB1,NETO1" MicroRNA hsa-miR-519b-5p:mirSVR_highEffct hsa-miR-519b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-518e*:mirSVR_highEffct hsa-miR-518e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-519c-5p:mirSVR_highEffct hsa-miR-519c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-519a*:mirSVR_highEffct hsa-miR-519a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-522*:mirSVR_highEffct hsa-miR-522*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-523*:mirSVR_highEffct hsa-miR-523*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-41 1.52E-37 9.58E-41 8.82E-40 117 735 "RALGAPA1,KCNH8,CLK4,KLHL32,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,CD86,CCPG1,NRXN3,CLCN3,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,RHOBTB1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,ADGRV1,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,HRASLS5,DISC1,ZNF638,GPD2,DHX35,ZNF546,KNDC1,NME9,CREG2,MAP2,MSR1,MYO9A,NELL2,NF1,NRCAM,SMIM11A,LOC100128398,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,TMEM260,GTDC1,DCUN1D2,ROBO2,ARMH4,RPS20,NCBP3,MAPK12,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,DBNDD2,SPART,LMO3,ITPRID2,SS18,KLHL7,SYT1,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,FAM124A,TP53BP2,NPL,METTL3,TSC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170" MicroRNA hsa-miR-3150:mirSVR_highEffct hsa-miR-3150:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.85E-41 1.60E-37 1.01E-40 9.28E-40 124 821 "CLK4,CCDC85A,CC2D2A,CARNS1,LTBP4,FGD2,BCAS1,ARRB1,CDK13,MPDZ,SEC11C,KALRN,SLC25A14,CAST,ARHGAP33,TIGD7,CFL2,NDST3,PPT2,ABCG2,AKAP6,COL11A2,CPS1,CLIP3,VCAN,GREB1,ZNF337,SPOCK2,SPOCK3,TMCC2,NYAP1,CPEB2,DOCK2,DTNB,SEZ6L2,EDN1,OPTN,APH1A,ENO2,RABEPK,SRRM1,ANKMY1,SIRPB1,PTK2B,PPP1R1B,UBE2E3,IP6K2,NELFCD,GAD1,B4GALNT1,MTHFD2,INPP5K,ALDH1L1,TXNL4A,HPGDS,LOXL3,GPD2,PCLO,CLASRP,PADI2,ARHGAP36,IDH3B,DISP2,NME9,SLC35G1,METTL21A,CREG2,KIF5A,CAMK2N2,HECTD2,NCOA7,MARK1,MBD1,MEIS2,MEST,MN1,LAYN,MYO7A,MYO9A,NNAT,NOVA1,OGG1,CLDN11,CDK18,PDE4D,PFKFB2,ZNF655,FAM216A,C19orf57,PPP2R2B,PRKACB,KLK6,PTPRH,RAP1GDS1,RASGRF1,SUGCT,C12orf49,GSTCD,NEK11,TRA2B,COPZ1,FAM214B,SIRT2,SMARCC2,SMARCD3,FNBP1,ATP10B,STAU1,SUPT5H,TPCN2,PCDHB4,ARHGAP9,FRYL,CCDC173,ZMAT3,TIMP4,KCNE5,UCHL1,OSBP2,SLC17A7,WNK3,UBE3B,PHTF2,NETO1" MicroRNA hsa-miR-431:mirSVR_highEffct hsa-miR-431:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.31E-41 1.85E-37 1.17E-40 1.08E-39 106 608 "CCDC85A,PWWP2A,ABCD2,SUGT1P4-STRA6LP-CCDC180,CCAR2,CHID1,ATP1A1,DPY19L3,ADAM23,KALRN,L3MBTL4,SOCS6,NRXN3,TPP1,WHRN,SLC4A8,AKAP12,RGS6,VCAN,PDE4DIP,GREB1,DOCK4,RIPOR2,ZFYVE16,RHOBTB1,SACS,CHRDL1,USP3,DTNB,KRBA2,TSPAN5,HIPK3,VPS13B,IGSF6,HSPA12B,CEP78,CHST15,FER,HPCAL4,IP6K2,FOLH1,ST6GALNAC3,MSANTD4,TRAF3IP2,DISC1,SULT1C4,DCLK2,GNAL,FAM107A,ADAMTS6,SMAP1,FAM69A,KCNN2,MBD1,MEIS1,MID1,XRRA1,GIT1,NRBP2,MYO9A,NRCAM,OXTR,PCSK5,PDE4B,XRN1,JAKMIP1,MTRF1L,PRIMPOL,PMP22,CNTLN,RAP1GDS1,RASGRF2,MSANTD2,EXD2,YY1AP1,CCDC102B,ATP8B4,SGK1,CPEB3,PPP4R3A,LIMCH1,KDM4C,LMO3,KANK1,CAMTA1,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TRO,RPL7L1,OSBP2,VLDLR,TRIM9,LYPD6,ZSCAN26,RNF103,WNK2,RTN4,FRMD6,NETO1" MicroRNA hsa-miR-548m:PITA hsa-miR-548m:PITA_TOP PITA 3.37E-41 1.89E-37 1.19E-40 1.10E-39 92 457 "PWWP2A,PTCHD1,BEND6,HECW2,FAM135A,OGT,DPP10,APAF1,EPB41L5,CDK13,SEPT7,CDH2,MAGI1,CCPG1,SRSF11,FOXN3,B4GALT6,CLCN3,QKI,SLC35F1,HAPLN1,KIAA0408,DOCK4,MYEF2,ALKBH8,CPEB2,FRY,CELSR3,PAN3,CEP78,FKTN,FGFR3,SUCO,UBE2E3,PDLIM5,ARFIP1,PCDH17,TCERG1,RNPS1,SPIN1,KDM2B,PCLO,CIT,ADAMTS6,HAS2,DDX19B,BACH2,TCEAL6,RBPJ,INSM1,KIF2A,STXBP5,MAP2,MEIS2,MXI1,NEXMIF,NOVA1,MINDY2,PTPRD,SLC25A36,ZFHX4,ZNF532,RORB,CLIP1,TNFRSF19,SCAF8,PPM1E,CPEB3,EPN2,CCDC88A,TRIM67,RCOR3,RGL1,ADAMTS17,PLCB1,ANKRD28,AGTPBP1,CRTC1,FRYL,DICER1,SLC44A1,KAT6B,VLDLR,KCNAB1,WNK3,PDSS2,MARCH8,KAT6A,NETO2,SOCS4,ST8SIA2,JPH3" MicroRNA hsa-let-7d:mirSVR_highEffct hsa-let-7d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.39E-41 1.90E-37 1.20E-40 1.10E-39 120 773 "KLHL32,ADRB2,RTL9,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,IGDCC4,ARHGDIA,SLC4A4,ZNF583,BACH1,GYG2,CH25H,TAOK2,NDST3,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,SEC24C,OSBPL3,PDE4DIP,BOC,DAPK1,B3GAT3,KLHL3,DMD,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,EIF4G2,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,CNTRL,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,RBPJ,ZNF678,FAM69A,NME9,KIF2A,MEIS2,CNOT4,NOVA1,OGG1,XRN1,PKIA,GDPD1,MASP1,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS12,RIC8B,LGI2,SETD5,EXD2,C12orf49,ROBO1,ATP8B4,ATXN7,FNIP1,KIF27,FNDC3A,HECW1,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCEA1,TCF12,CDH22,MTMR14,FAM124A,TPM2,PDSS1,VSNL1,RICTOR,LYPD6,ZSCAN26,SMARCAD1,STOX2,PHTF2,GAN" MicroRNA hsa-miR-3180-3p:mirSVR_lowEffct hsa-miR-3180-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-41 1.92E-37 1.21E-40 1.11E-39 108 631 "RNF157,PWWP2A,BEGAIN,AMH,EP400,CDK10,MADD,SPTBN4,ARHGDIA,ARHGDIG,ATP1A3,KSR1,CAMK2G,USP2,ARHGEF1,ENTPD2,EVI5L,NUMBL,NRXN3,CCDC151,FAM149A,ZNF385A,ANKRD44,NCOR2,GDA,RUSC2,HS3ST2,DTNB,ANKRD46,CELSR3,EIF1,MTSS1L,EPHB1,SRRM1,SPEG,REEP2,PTK2B,KAT8,BAIAP2,PRKAG2,AGAP2,ERGIC3,ZNF274,ALDH1L1,TUBA8,ZNF276,STMN2,GRB10,C1QL4,LINGO1,MUM1,PACSIN2,HMGCL,IDH3A,LRRC25,KNDC1,L1CAM,PPM1L,XRRA1,MSI1,RTL5,FXYD7,OGG1,PCSK5,PDE4A,GPR173,PFKFB3,NLGN3,CCSER2,PLEC,PILRA,POLR2F,CNNM2,SUSD4,PRRT2,KCTD17,ATAT1,STX1B,ARX,MYO18A,HKDC1,FAM81A,SLC12A4,KIF13A,SNRPN,IQSEC2,TSPYL2,MCF2L2,STX1A,SYN1,SYN2,EXOC7,PDLIM2,TCF4,NEU4,NAT16,TNS2,TMEM121,PIK3R5,RASD2,NPL,C9orf85,SMUG1,CLEC2L,ZIC2,GDPD5,PRDM8,TMEM178A" MicroRNA hsa-miR-222:PITA hsa-miR-222:PITA_TOP PITA 3.57E-41 2.00E-37 1.26E-40 1.16E-39 72 270 "RALGAPA1,AXIN2,PTCHD1,LRFN2,PITPNM2,APAF1,ATP1A1,BCHE,KSR1,CNR1,ZNF385A,RGS6,SEC24C,RIMS4,USP6NL,ZFYVE16,SPATA2,MYEF2,CDON,ARRDC4,EMX2,ERBB4,SEC24B,SMC2,PPARGC1A,FERMT2,PRRC2B,GRB10,ADAMTS6,ZHX1,MIER3,AGFG1,INSM1,KIT,STMN1,MARK1,MAT2A,ADAM11,MEIS1,NEFH,NOVA1,KSR2,PCSK1,PIK3R1,PDZRN4,PPP2R5E,KANSL1,MAPK10,KHDRBS2,SEMA6D,KIF16B,CPEB3,FNDC3A,WDR37,WDR47,CCDC88A,TMCC1,CDK19,POGZ,CAMTA1,CUX2,TRIM2,TCF12,DICER1,SIRT1,ZFPM2,TIAM1,TRPS1,SLC35A4,TUBA1A,HNRNPA3,SOCS4" MicroRNA hsa-miR-204-5p:TargetScan hsa-miR-204-5p TargetScan 4.35E-41 2.43E-37 1.53E-40 1.41E-39 102 565 "NDRG3,ADCY6,RNF157,ESYT2,AP2A2,KLHL13,BIN1,OGT,ARRB1,CDK13,MARCH3,DYNLL1,BCL7A,RUNX1T1,MTMR7,CDH2,CCPG1,CHN2,PLAA,FHL5,PCYT1B,SEC31B,HAPLN1,CNTNAP2,CTH,RIMS2,HDAC9,GAPVD1,DCAF8,DGKG,DNAL1,ELMSAN1,GUCD1,RHOBTB1,FAM107B,DMTF1,CELSR3,EIF1,RPS6KC1,ACSL4,SCML2,AGAP2,ANKFY1,NBEA,KHDRBS3,NSG1,GABRB3,GCNT2,PPARGC1A,GPT2,HAS2,FRMD5,NCKAP1L,MIER3,HMGCR,IL6R,INSM1,JAK2,IPO5,NCOA7,LSAMP,MBD1,MBNL1,MEIS1,MEIS2,MGAT3,SAMD5,MXI1,NOVA1,P2RX7,PDE3A,PDE4A,POLR2F,PTPRD,PTPRG,CCDC40,GTDC1,KLHL11,ROBO1,RORB,FBXW7,CSRNP3,FNIP1,HSPA4L,PPM1E,ARX,MYO18A,BTBD7,CPEB4,MBD5,PEG10,ARHGAP26,ANKRD12,DNMBP,SATB2,ASXL3,RICTOR,REEP1,ADAMTS9,RNF170,GAN,JPH3" MicroRNA hsa-miR-211-5p:TargetScan hsa-miR-211-5p TargetScan 4.35E-41 2.43E-37 1.53E-40 1.41E-39 102 565 "NDRG3,ADCY6,RNF157,ESYT2,AP2A2,KLHL13,BIN1,OGT,ARRB1,CDK13,MARCH3,DYNLL1,BCL7A,RUNX1T1,MTMR7,CDH2,CCPG1,CHN2,PLAA,FHL5,PCYT1B,SEC31B,HAPLN1,CNTNAP2,CTH,RIMS2,HDAC9,GAPVD1,DCAF8,DGKG,DNAL1,ELMSAN1,GUCD1,RHOBTB1,FAM107B,DMTF1,CELSR3,EIF1,RPS6KC1,ACSL4,SCML2,AGAP2,ANKFY1,NBEA,KHDRBS3,NSG1,GABRB3,GCNT2,PPARGC1A,GPT2,HAS2,FRMD5,NCKAP1L,MIER3,HMGCR,IL6R,INSM1,JAK2,IPO5,NCOA7,LSAMP,MBD1,MBNL1,MEIS1,MEIS2,MGAT3,SAMD5,MXI1,NOVA1,P2RX7,PDE3A,PDE4A,POLR2F,PTPRD,PTPRG,CCDC40,GTDC1,KLHL11,ROBO1,RORB,FBXW7,CSRNP3,FNIP1,HSPA4L,PPM1E,ARX,MYO18A,BTBD7,CPEB4,MBD5,PEG10,ARHGAP26,ANKRD12,DNMBP,SATB2,ASXL3,RICTOR,REEP1,ADAMTS9,RNF170,GAN,JPH3" MicroRNA hsa-miR-25*:mirSVR_lowEffct hsa-miR-25*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-41 2.63E-37 1.65E-40 1.52E-39 117 739 "ADD1,UNC5A,LRFN1,ZFAT,PPFIA4,APBB2,PHYHD1,BCAS1,SFMBT2,SPTBN4,NCOA1,ATP2B2,SLC16A4,ASIC3,TAOK2,EPS15L1,NRXN3,PPT2,MYL6B,SMARCAL1,CLOCK,NCOR2,CSF1,CSF2RA,MYADM,SPOCK2,TIAM2,RPS6KL1,ARRDC4,PHF20L1,RASA4,EIF1,EPB41,ANKMY1,ABCA8,ZNF461,SCML2,FCGRT,FGF11,POLK,NOP56,TRIM16,DLL3,FYB1,INPP5K,GRIN2D,CIT,KAT7,ATOH8,UBE2QL1,HMGCL,FAM95B1,LRRC25,SLC6A17,INSM1,KHK,A1BG-AS1,NCOA7,MAN2A2,AFF1,MT1M,SFR1,SLC11A2,PDE4A,PDE1B,PFKFB3,ZNF655,CCSER2,FAM216A,SMOX,FXYD1,SCHIP1,NKAIN4,GRAMD1C,PTPRG,CCDC40,RNASEL,YY1AP1,EPHA10,BAALC,ZNF331,FAM102A,FRMPD1,MYO18A,ST6GAL1,SLC22A4,RCOR3,ANKRD36,KIF13A,FAIM2,SNRPN,FAM219A,FNBP1,ZSWIM8,SYN1,IQCE,SYNE1,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,RASD2,C9orf85,SMUG1,LGI4,ZNF708,POLR3H,EMSY,DNALI1,HPS4,TRIM16L" MicroRNA hsa-miR-568:PITA hsa-miR-568:PITA_TOP PITA 5.45E-41 3.05E-37 1.91E-40 1.76E-39 97 512 "PTCHD1,ZNF608,OSBPL8,ALCAM,GAS7,CDC14B,SLC4A4,FUBP1,NUMBL,CHN2,IGDCC3,CSNK1G3,SOCS5,PHACTR3,PUM1,MATR3,MAML1,DDX46,RHOBTB1,SPOCK3,DLX1,MAMLD1,EIF5,MED12L,NBEA,FUT9,CHL1,GABRB3,PPARGC1A,SPIN1,KDM2B,FAM19A2,PSIP1,ZHX1,MIER3,HLF,ELOVL5,AGFG1,IGF1,ZIC5,IPO5,PACRG,MAP2,MARK1,MATN2,LRP1B,MEIS1,KITLG,MITF,NF1,NFIX,KSR2,XRN1,STRN3,PRKAB2,GDPD1,TMEM260,PTPRG,TMEM255A,SH3TC2,OXR1,REV3L,RORB,ZC3H14,SEMA6D,SUPT20H,FHOD3,NLGN1,ELMO2,CPEB4,SMARCA4,PDZRN3,PDZD2,SP4,HECW1,MYCBP2,ADAMTS17,SYT1,ANKRD28,ANKRD12,FBXW11,TCF4,TCF12,LRRC8A,RIMBP2,CSMD1,KAT6B,FAM155A,XPO1,ZBTB38,SMARCAD1,CADM2,RGS7BP,FAM13C,FRMD6,ST8SIA2,CPNE4" MicroRNA hsa-miR-450b-3p:mirSVR_highEffct hsa-miR-450b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.06E-41 3.39E-37 2.13E-40 1.96E-39 101 556 "ADCY6,KIAA1211,BEND6,OLMALINC,KLHL13,ADGRF5,AMT,PKP4,USP37,PLA2G4C,CFLAR,CLDN10,C1orf52,IGLON5,SUMF2,FAM171B,ANKRD44,SNCAIP,SLITRK5,GPRASP1,ARMCX4,JAKMIP2,ELMO1,WDR20,EXOG,GRIN3A,DMTF1,FARSB,EDN1,EDN3,FCF1,APH1A,GOLGA7,DCTN4,ENO2,SRRM1,CDKL3,F5,F8,FDFT1,KAT8,POLK,GABRG2,B4GALNT1,MAP7D2,PRDM5,FAM19A2,FAM222A,FRMD3,HLF,HNF4G,HNMT,LRRC75A,ZNF667-AS1,MEIS2,SRSF12,MEST,MYO7A,CNOT4,NOVA1,PCSK5,PCDH18,PPP2R5E,RASGEF1B,PRKAR1B,MAPK10,GRAMD1C,HYDIN,PTPRE,PTPRG,OXR1,HKR1,PBRM1,SUGCT,C12orf49,ADAL,SCN8A,SEC14L1,CCDC92,WDR47,INTS9,RCOR3,LIMCH1,KDM4C,SPART,POGZ,ANKRD28,TACR1,SATB2,RNF175,AP4E1,ASXL3,SYNPO2,TUBB1,VLDLR,ZNF708,MICU3,ZNF154,INTS3,PRDM8,FXR1" MicroRNA hsa-miR-4287:mirSVR_highEffct hsa-miR-4287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.33E-41 3.54E-37 2.22E-40 2.05E-39 121 790 "ASIC1,NDRG3,KLHL32,GALNT13,PTCHD1,RTL9,TAOK1,SPOP,CDC42BPA,UPRT,BCAS1,NUMB,RIPK1,CASTOR3,C5,CALB1,CAST,CCNH,CDH2,LRRFIP1,NDST3,CLCN3,FHL5,AHCTF1,ZFP28,RBM39,RIMS2,CYBB,LONRF1,DGKB,BRINP1,HEPH,ALKBH8,FAM107B,EXOG,HS3ST2,DMTF1,PDCD6IP,ARRDC4,DNM1L,PHC2,KLHL5,AASS,EPHB1,SRRM1,SUCO,HPCAL4,GABBR1,ZNF559,ARFIP1,CBX1,STMN2,DIDO1,SERP2,FAM19A2,MAP4K5,IRAK3,TOX2,ELOVL5,LRRCC1,INSM1,TTYH2,MEIS1,ZNF862,NDP,CNOT4,NTRK2,PDE1B,GNG2,RETREG1,ANKRD16,LRP12,SEPT4,SH3KBP1,POLR2F,PKIA,EPDR1,MAPK9,MAPK10,VPS13C,GDPD2,PTN,TRIM68,CCDC82,TMLHE,CARF,ROBO2,ATP8B4,MEG3,AP1AR,ATXN2,SCN7A,ASAP3,FHOD3,SLA,ARHGEF40,SLC9A5,ZSWIM8,UHRF1BP1L,ATP10B,ITPRID2,SSTR2,ZC4H2,RGL1,ADHFE1,SYP,SYPL1,FAM208A,TBCEL,FRYL,GPR161,CDH22,NR2E1,TSN,UBE3A,PLEKHH2,PRDM10,ADAMTS9,ITM2C,DOCK8,GJC2" MicroRNA hsa-let-7f:mirSVR_highEffct hsa-let-7f:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.92E-41 4.43E-37 2.78E-40 2.56E-39 124 829 "KLHL32,BRAP,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CH25H,TAOK2,NDST3,PPT2,QKI,MAP4K4,AHCTF1,IGDCC3,OSBPL3,PDE4DIP,BOC,DAPK1,B3GAT3,KLHL3,DMD,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,RACK1,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,BRD8,POLL,FUT10,CNTRL,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,LRRC25,NKD1,FAM69A,NME9,MEIS2,CNOT4,NOVA1,OGG1,FAM218A,XRN1,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,ATXN7,FNIP1,KIF27,FNDC3A,BDP1,HECW1,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCF12,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,VSNL1,RICTOR,LYPD6,ZSCAN26,SMARCAD1,STOX2,PHTF2,GAN" MicroRNA hsa-miR-410-3p:TargetScan hsa-miR-410-3p TargetScan 7.99E-41 4.47E-37 2.80E-40 2.58E-39 89 431 "C3orf14,FMNL2,ELFN2,ADD2,RNF150,KCTD16,HACE1,LCORL,PARG,APAF1,CASK,CDK13,PDE8B,NUMB,ATP2B2,CALM1,KRIT1,CCNT1,DGKI,CFL2,NRXN3,FAM19A5,QKI,IQCK,ARMC8,AHCTF1,HAPLN1,CSF1,OSBPL3,ARHGAP24,MATR3,IP6K1,MFAP3L,CDON,DPYSL2,DTNA,KLHL5,PLXNC1,RGS17,FGFR3,PSD2,MPP6,RAPGEF6,ARFIP1,LOXL3,PRRC2B,PRUNE2,GRIA2,PARD3B,RASSF8,HLF,IGF1,ITPKB,KIT,LSAMP,SCAMP5,AFF1,MMP16,NPTX2,PCDH8,PCSK5,PDE3A,PDPK1,PTPRB,CEP97,RDX,PRIMA1,PBRM1,RORB,MCMBP,SCN2B,HSPA4L,CPEB3,ABLIM3,ARHGEF40,ELMO2,CPEB4,MBD5,PDZD2,KDM3A,CDK19,POGZ,ANKRD12,RGMB,MAP3K12,PPP1R3F,KAT6A,HNRNPA3,NETO1" MicroRNA hsa-miR-485-5p:mirSVR_highEffct hsa-miR-485-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.80E-41 4.92E-37 3.08E-40 2.84E-39 126 855 "SYN3,NDRG3,RTL9,WDR35,TAOK1,AMPD2,OGT,PDE8B,NUMB,ATP2B2,RNF182,DPY19L3,DST,BTK,BAIAP3,USP2,RGN,ARHGEF1,AP4M1,LRBA,TIGD7,CHN2,RAB33A,ARMC8,SUMF2,NCOR1,TRIM69,SEC24C,PDE4DIP,EARS2,RUSC2,SLC29A4,DTNA,PHC2,RASGRP1,IRAK4,EPB41L2,ACSL4,STRADA,FDFT1,PRMT5,SEC24B,NBEA,KHDRBS3,CELF1,OGA,DENND2A,GALC,RAPGEF6,GGT7,PPARGC1A,GLI2,GNAL,ZNF782,TDRKH,GPR34,ICA1,CREG2,MEIS1,MYO7A,MYT1,P2RY13,NFE2L2,NOVA1,OPA1,PMP22,MBOAT7,FSD1,PRKACB,SAMD9,BCAS3,CNTLN,SPDL1,PTPRE,ZSCAN2,RDX,DPF2,RIC8B,ZFHX4,SPIN3,ABCA11P,FAM192A,SHC4,CHD9,PPP4R3A,KBTBD4,ELMO2,ATF7IP,ZFP1,MAST1,RCOR3,INAVA,SNCA,KIF13A,CABCOCO1,ANKFN1,ZSWIM8,KDM4C,SPART,SYPL1,MTCL1,FBXW11,TPCN2,HIF3A,SIK3,FAM124A,KAT6B,WBP2,ZNF346,UGT8,PLPPR2,CCDC136,RICTOR,ZNF17,ZNF540,ATP6V0E2,CADM2,LINC02210,URM1,WNK3,NELFE,PLSCR4,PARP11,EPM2A,PHTF2,FAM198A" MicroRNA hsa-miR-4297:mirSVR_highEffct hsa-miR-4297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-40 6.06E-37 3.79E-40 3.49E-39 104 593 "ZNF608,HECW2,OSBPL8,AK2,SUGT1P4-STRA6LP-CCDC180,AQP6,ARNTL,BARD1,ZNF599,KSR1,DST,CASTOR3,CALB2,THSD7A,CALM1,CAMK2G,CHN2,SUMF2,SLC4A8,SLITRK5,DZIP3,UBXN2A,DOCK4,KIAA0586,ARMCX4,GSDME,EXOG,RAB39B,CPEB2,EDIL3,CNNM1,SEMA3D,SRRM1,MRPL37,NRN1,SCML2,FER,FGFR1,GABBR1,SYT17,DISC1,RAB30,RAB40B,GRIA2,PLCD4,RNF165,UBE2QL1,PACSIN2,ZNF491,SHISA6,EID2B,MYLK2,RBPJ,STMN1,SYTL4,SHC3,MEIS1,NRBP2,NDP,CCDC13,DNHD1,GPR137C,FAM216A,PLCB2,PTN,PTPRE,RDX,MORC4,EXD2,KIAA0895L,ATP8B4,SGSM1,ZNF331,SEPHS1,PDZRN3,LMO3,MPRIP,TACC1,ADGRL3,CUX2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,ARL10,KAT6B,C9orf85,RGMB,RPL7L1,ZNF709,ZIC1,TCEAL7,ANKS1B,SPIRE1,SMARCAD1,DNALI1,KCNAB1,DOCK8,TIGD6" MicroRNA hsa-miR-133a:mirSVR_highEffct hsa-miR-133a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.24E-40 6.94E-37 4.34E-40 3.99E-39 107 628 "SLC24A4,CC2D2A,PITPNM2,LCORL,CDK13,PDE8B,TTLL9,SEC11C,BMP7,KALRN,PTBP2,VXN,CAST,NFS1,CLDN10,CD86,LRBA,SLC4A8,TBPL1,ZFP28,CNRIP1,HAPLN1,ANKRD44,CSNK1G3,CTH,BOC,MAML1,IST1,ZC3H11A,DMTF1,DPP6,ANKRD46,EGFR,TENM1,PAN3,COQ7,CEP85L,MED12L,SMC2,SPECC1,GALNT15,ALDH1L1,SRCAP,POLL,GPD2,TDRKH,ATOH8,CFAP126,RBPJ,LAMP2,NCOA7,MEIS1,MEIS2,MEST,NME4,NPTX2,DPY19L2P2,PDE1C,TRHDE,ING3,SEPT4,PRKCB,SAMD9,SNRK,CNTLN,PTH1R,TMEM260,PTPRD,PTPRH,PTPRO,PRRT2,ERI2,RGS3,EXD2,CARF,ZC3H14,KCNIP1,CSRNP3,SGK1,FRMPD1,FHOD3,BTBD3,ZFP1,SNCA,SNRPN,ZSCAN29,SYT1,ANKRD28,TACC1,ANKRD12,TBCEL,FBXW11,ARHGAP9,CHST8,C18orf54,AP4E1,NPL,ELP5,AMACR,DCBLD1,TUBB1,ELFN1,CELF4,PLSCR4,DOCK8,KAT6A,HNRNPA3" MicroRNA hsa-miR-133b:mirSVR_highEffct hsa-miR-133b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.24E-40 6.94E-37 4.34E-40 3.99E-39 107 628 "SLC24A4,CC2D2A,PITPNM2,LCORL,CDK13,PDE8B,TTLL9,SEC11C,BMP7,KALRN,PTBP2,VXN,CAST,NFS1,CLDN10,CD86,LRBA,SLC4A8,TBPL1,ZFP28,CNRIP1,HAPLN1,ANKRD44,CSNK1G3,CTH,BOC,MAML1,IST1,ZC3H11A,DMTF1,DPP6,ANKRD46,EGFR,TENM1,PAN3,COQ7,CEP85L,MED12L,SMC2,SPECC1,GALNT15,ALDH1L1,SRCAP,POLL,GPD2,TDRKH,ATOH8,CFAP126,RBPJ,LAMP2,NCOA7,MEIS1,MEIS2,MEST,NME4,NPTX2,DPY19L2P2,PDE1C,TRHDE,ING3,SEPT4,PRKCB,SAMD9,SNRK,CNTLN,PTH1R,TMEM260,PTPRD,PTPRH,PTPRO,PRRT2,ERI2,RGS3,EXD2,CARF,ZC3H14,KCNIP1,CSRNP3,SGK1,FRMPD1,FHOD3,BTBD3,ZFP1,SNCA,SNRPN,ZSCAN29,SYT1,ANKRD28,TACC1,ANKRD12,TBCEL,FBXW11,ARHGAP9,CHST8,C18orf54,AP4E1,NPL,ELP5,AMACR,DCBLD1,TUBB1,ELFN1,CELF4,PLSCR4,DOCK8,KAT6A,HNRNPA3" MicroRNA hsa-miR-647:mirSVR_highEffct hsa-miR-647:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-40 7.20E-37 4.50E-40 4.14E-39 110 663 "ABHD6,NCKAP5,BEND6,HECW2,OSBPL6,ALCAM,AMPD2,ANK2,USP37,RGS20,CCDC74A,CHRD,NCOA1,TTLL9,RGS9,SYNJ2,THSD7A,KALRN,CAMK2G,CBR1,CERS5,CHGB,EPS15L1,CLTC,ARHGEF6,IQCK,ARMC8,ZNF521,IGDCC3,GDA,VAC14-AS1,DZIP3,CTH,RIMS2,RUBCN,KIF26A,DAPK3,USP3,NR1D2,CPEB2,FAM78B,FSD1L,OPTN,PHF20L1,ELN,TMEM35A,RABEPK,ERCC2,KAT8,GORAB,SEMA4D,CAMKK2,KHDRBS3,MSANTD4,MTHFD2,HPGDS,DCLK2,CCDC184,GRIA2,PLCD4,ZBTB49,SYNPO,AGBL5,ICA1,INPP5B,KPNA5,LAMP2,HECTD2,MEIS1,KITLG,NF1,NPY,NOVA1,ZNF827,PCSK5,MAPK7,GRAMD1C,STK32A,PTPRB,IQSEC3,MSANTD2,GTDC1,ZFHX4,MEG3,ABCA11P,S100B,SCN8A,SEC14L1,SUPT20H,ELMO2,OGDHL,SMARCD3,RCOR3,ANKRD36,MBD5,NFASC,PBLD,SS18,SYNE2,SIN3B,ZEB1,HIF3A,TEK,R3HDM1,C9orf85,METTL3,ZNF19,DNALI1,STOX2,SMIM8" MicroRNA hsa-miR-1256:mirSVR_highEffct hsa-miR-1256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-40 7.44E-37 4.64E-40 4.27E-39 106 617 "KCNH8,MARCH4,PCDH10,DPP10,FGD2,ARRB1,PLA2G4C,ASGR1,ZNF582,SLC2A11,N4BP2L1,ATP6V0A1,BMPR1B,CACNA1B,CD38,LOC730101,CFL2,SRSF11,SOCS6,CPNE6,PPT2,CNR1,AKAP7,AKAP6,COL4A5,MYRIP,CREM,CLIP3,SNCAIP,CSNK1E,VCAN,CYBB,IP6K1,DBI,DDX46,RHOBTB1,DPP6,DTNA,E2F5,EDNRA,EMX2,TMEM132C,SLC9B2,OLFM1,NOP56,CAMKK2,ZNF605,ZNF234,ERAP1,NEU3,GPD2,PRUNE2,RNFT2,FRMD3,ELOVL5,C9orf129,FAM95B1,C2orf72,ZIC5,RBPJ,LIG4,CLEC18A,EFHB,NFE2L2,NTRK2,P2RY1,PCDH9,PDE1C,GPR85,PIK3C2A,MTRF1L,PDZRN4,ING3,DRAM2,MAPK9,MASP1,PEX2,TMEM255A,SH3TC2,RGS3,NUDT11,RORB,AP1AR,SALL1,SCN8A,SCP2,SGK1,CCDC88A,DMRTC1,SNRPN,DDN,SYNE2,VPS13A,ANKRD28,DMXL2,ZFP90,CUX2,SYNE1,ASXL3,NR2E1,METTL3,STXBP4,BCL2L13,TRIM9,DNAH10,PHTF2" MicroRNA hsa-miR-133a-3p.1:TargetScan hsa-miR-133a-3p.1 TargetScan 1.45E-40 8.13E-37 5.07E-40 4.66E-39 87 414 "ADCY6,OSBPL8,PITPNM2,ARHGDIA,ARRB1,CDK13,PCDHGB4,BACH1,JAZF1,MYRF,DDR1,CALM1,PTBP2,CAMK2G,RUNX1T1,ARHGEF2,CLTC,QKI,HAPLN1,ANKRD44,CSNK1G3,KIAA0040,SEC14L5,CCDC144A,GAPVD1,MAML1,IP6K1,DNAL1,ELMSAN1,DNAJB6,FAM13A,PAN3,ERBB2,CEP85L,ACSL4,MED12L,FGF1,FGFR1,HPCAL4,CAMKK2,CELF1,DOT1L,RAPGEF6,ATOH8,FRMD5,CELF5,RBPJ,IL6ST,MEIS1,MEIS2,MYO9A,NFYA,NNAT,PCDHGC3,GPR173,PFKFB3,PIK3C2A,KCTD15,SDK2,PTH1R,PTPRD,PRRT2,RFX3,KLHL11,EXD2,C12orf49,SCN2B,CASC3,BTBD3,MYCBP2,ANKRD28,ANKRD12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ARHGAP9,GPR161,ELFN1,DOCK8" MicroRNA hsa-miR-603:Functional MTI Functional MTI miRTarbase 1.75E-40 9.78E-37 6.09E-40 5.61E-39 96 508 "ESYT2,MTA3,KCTD16,TAOK1,LRFN1,TNRC6C,DPY19L3,BACH1,JAZF1,CA8,CDH2,TBRG4,CFL2,B4GALT6,TBPL1,CRY2,ANKRD44,MYADM,LONRF1,SPOCK2,DBT,KLHL3,SV2B,EGR3,PLXNC1,EIF5,C8orf37,TUBD1,CHST15,AFF2,ZBED3,MPP6,HRASLS5,SYT17,SEPT9,GCK,SRCAP,PPARGC1A,PARD3B,CACFD1,GSN,FICD,ATOH8,HLF,IGF1,SCIN,IL6ST,KCNB1,KLHL23,SYTL4,NEXMIF,P2RY1,TMOD2,PIK3R1,PLCL1,SNRK,RDX,ZMAT4,GTDC1,C12orf49,ATAT1,SBF1,CSRNP3,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,TRERF1,UNC5B,SS18,NECAB1,SYT5,TPCN2,GPRIN3,SIK3,SLC44A1,GALNT17,NACC2,BHLHB9,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,NDRG4,CRB2,ZXDA,ADAMTS9,HPS4,WNK3,FAM198A,SPATA13" MicroRNA hsa-miR-221-3p:TargetScan hsa-miR-221-3p TargetScan 1.83E-40 1.03E-36 6.39E-40 5.88E-39 83 376 "RALGAPA1,AXIN2,PTCHD1,LRFN2,PITPNM2,PHF12,INSYN2B,KSR1,ARHGEF7,MTMR2,CACNB4,PTBP2,RUNX1T1,CDH2,MAGI1,NDST3,QKI,AKAP5,OSBPL3,RIMS4,PLCXD3,DNAL1,MYEF2,CDON,HIPK3,FRY,EGFR,PLXNC1,RGS17,EIF1,EMX2,ERBB4,FGF14,RNPS1,GNAL,GPR12,GRB10,MIER3,AGFG1,MSL1,IGF1,KCNQ3,KIT,LIFR,HECTD2,MARK1,ADAM11,MEIS1,MITF,DBNL,ADAM22,NOVA1,PDE3A,PIK3R1,PDZRN4,PPP2R5E,KANSL1,PKIA,MAPK10,ANKHD1,KHDRBS2,REV3L,FIGN,RFX3,KIF16B,CPEB3,FNDC3A,CCDC88A,MBD5,POGZ,MPRIP,FAM208A,CUX2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,EML6,HNRNPA3" MicroRNA hsa-miR-222-3p:TargetScan hsa-miR-222-3p TargetScan 1.83E-40 1.03E-36 6.39E-40 5.88E-39 83 376 "RALGAPA1,AXIN2,PTCHD1,LRFN2,PITPNM2,PHF12,INSYN2B,KSR1,ARHGEF7,MTMR2,CACNB4,PTBP2,RUNX1T1,CDH2,MAGI1,NDST3,QKI,AKAP5,OSBPL3,RIMS4,PLCXD3,DNAL1,MYEF2,CDON,HIPK3,FRY,EGFR,PLXNC1,RGS17,EIF1,EMX2,ERBB4,FGF14,RNPS1,GNAL,GPR12,GRB10,MIER3,AGFG1,MSL1,IGF1,KCNQ3,KIT,LIFR,HECTD2,MARK1,ADAM11,MEIS1,MITF,DBNL,ADAM22,NOVA1,PDE3A,PIK3R1,PDZRN4,PPP2R5E,KANSL1,PKIA,MAPK10,ANKHD1,KHDRBS2,REV3L,FIGN,RFX3,KIF16B,CPEB3,FNDC3A,CCDC88A,MBD5,POGZ,MPRIP,FAM208A,CUX2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,EML6,HNRNPA3" MicroRNA hsa-miR-922:PITA hsa-miR-922:PITA_TOP PITA 1.97E-40 1.10E-36 6.86E-40 6.31E-39 84 386 "ASIC1,ACTN1,NDRG3,FMNL2,AP2A1,ZNF608,PCDH19,SEMA6A,ZBTB10,ATP1B3,ADGRB3,BCL7A,CALB1,HAP1,CAMK2G,CH25H,LARGE1,DLGAP2,QKI,FHL5,LETMD1,OSBPL3,CSNK1G3,SOCS5,LONRF1,IST1,BRINP1,MYEF2,SACS,HS3ST2,DYNC1I1,CPEB2,HIPK3,APH1A,GOLGA7,PAN3,EPB41,SRRM1,ETV1,NRN1,TAOK3,CSPG5,SRRM4,KDM2B,GPD1,GRIA2,BACH2,MAP4,MBNL1,CHIC1,LRP1B,MEIS2,MN1,GPR137C,GPR85,SEMA5B,PLEC,STRN3,PPP2R2B,PKIA,CNNM2,PSD,FIGN,FBXW7,KCNIP1,SAFB,SMPD3,FNDC3A,LGI3,SNCA,SOX11,LMO3,ST5,PRRC2C,CAMTA1,TCF4,DICER1,AMACR,UCHL1,ZNF711,REEP1,SMARCAD1,KCNAB1,JPH3" MicroRNA hsa-miR-770-5p:mirSVR_highEffct hsa-miR-770-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-40 1.22E-36 7.56E-40 6.96E-39 92 467 "CCDC85A,OSBPL6,CC2D2A,CARNS1,OGT,FGD2,PHF12,CHRD,EIF4G3,ADAM23,CBLN1,CNR1,RCHY1,SIPA1L1,GREB1,IST1,ARMCX2,ZNF804A,SACS,TMCC2,DNM1,CPEB2,SLC12A6,DTNA,DNM1L,WDPCP,KMT5B,AASS,EMX2,RCAN2,EPHB1,TLR7,RRAGB,ADGRV1,ST3GAL6,KAT8,ZNF589,SEC23B,ANKFY1,STAU2,NEU3,PCLO,GRIA2,TJAP1,IL6ST,METTL21A,STMN1,MARK1,MATN2,ZNF680,ADAM22,MYO6,NCAM2,P2RY1,CDK18,MAPKAP1,STRN3,CNTLN,PTX3,FAT4,RAP1GDS1,OXR1,HKR1,GTDC1,SLC25A36,CCDC82,ELP2,CCDC102B,NEK11,FBXW7,ATAT1,ZNF331,RMI1,LRFN5,SH3BGR,HKDC1,FHOD3,ATF7IP,DOK5,SP4,POGZ,MESP1,ELOVL4,PCDHB3,ZFPM2,TP53BP1,HIRA,SGK3,ZNF138,ZNF154,ADAMTS9,TMEM178A" MicroRNA "TAATAAT,MIR-126:MSigDB" "TAATAAT,MIR-126:MSigDB" MSigDB 2.77E-40 1.55E-36 9.62E-40 8.86E-39 63 205 "HECW2,TAOK1,ADGRF5,ALCAM,OGT,LRCH2,MARCH3,ZNF583,ADGRB3,DDR1,SPAG9,RUNX1T1,NFS1,FOXN3,AHCTF1,LRRC3B,HDAC4,MYEF2,USP3,SRRM1,EYA1,AFF2,SRRM4,GHR,PPARGC1A,DCLK2,GRIA2,GRM8,NKD1,KCND2,KCNH2,MATN3,MIA2,MID1,MMP16,MYT1,ZC3H12B,NOVA1,NTRK2,ING3,PPP2R5E,ZFHX4,ZNF354C,SEMA6D,FNDC3A,UHRF1BP1L,CDK19,ERBIN,TCF12,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TRPS1,FLRT2,TBC1D15,ZIC1,PRDM8" MicroRNA hsa-miR-380:PITA hsa-miR-380:PITA_TOP PITA 3.13E-40 1.75E-36 1.09E-39 9.99E-39 85 398 "PWWP2A,PCDH19,OSBPL8,OGT,LRCH2,ZBTB10,SLC4A4,DPY19L3,MTMR2,CACNB4,KALRN,KRIT1,ZFYVE16,TIAM2,DMD,GOLT1B,KLHL5,EIF4G2,CLVS1,SMC2,CAMKK2,OGA,C15orf41,PCDH17,GPD2,STON1,ATXN2L,BACH2,HMGCR,AGFG1,KIF2A,MAP2,AQP11,MBNL1,MEF2C,KITLG,MYO5A,GLIPR1L2,CNTN3,PCDH8,SH3KBP1,SNRK,PTPRE,TMEM255A,RADX,RDX,FIGN,UBR7,DCUN1D2,ALG9,SMPD3,SHC4,CHD9,FNDC3A,WDR37,CCDC88A,CPEB4,SNAP25,FAM126B,SOX11,SP4,ZNF423,CDK19,RBM26,CLASP2,LARP4,STAU1,ADAMTS17,PLCB1,AGTPBP1,PUM2,ZFPM2,NR2C2,TRPS1,UBE3A,FLRT2,VSNL1,XRCC4,SMARCAD1,RGS7BP,FAM13C,HNRNPA3,PHTF2,FXR1,SENP7" MicroRNA hsa-miR-3146:mirSVR_highEffct hsa-miR-3146:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-40 1.77E-36 1.10E-39 1.01E-38 111 681 "TXNDC16,ABCD2,CARNS1,DPP10,APC,SPTBN4,ARRB2,ZNF583,AZGP1,BCHE,SCAPER,CALB1,THSD7A,CBR1,MAGI1,CNOT8,CPNE6,DGCR9,QKI,CNN3,FAM149A,COL4A5,GDA,PDE4DIP,GREB1,HDAC9,CENPL,KCTD8,KIAA0753,GRIN3A,DNAH9,CASP8AP2,DTNA,ECM2,GOLT1B,E2F5,EDNRB,ANKRD46,GOLGA7,C8orf37,CALCRL,DCTN4,CEP85L,F8,POLK,SEC23B,DCTN2,CAMKK2,OGA,GALC,DISC1,KIAA1841,GHR,MAP7D2,GPD2,GPR34,SOX21,LRRTM1,SLC35G1,KCNH2,CYP27C1,MAP4,MAT2A,KCTD6,ADAM22,MYO9A,NCF2,SLC11A2,OCRL,P2RY1,JAKMIP1,PRKCB,HYDIN,CNTLN,BDNF-AS,TMEM255A,GTDC1,RIC8B,PBRM1,FBXO11,CNKSR2,SLA,DHX30,CDK5RAP2,ITPRID2,NUDT10,ADGRL3,TCEA1,ZEB1,TRIM2,TCF12,ERCC6L2,FAM124A,WBP2,TRIO,UBE2H,UGT8,TBC1D15,WIPF1,CLDND1,XRCC4,MICU3,KCNT2,ZNF74,LYPD6,TMEM237,DPYSL5,ZNF225,NAV3,EPM2A,AMN1" MicroRNA hsa-miR-483-3p:mirSVR_highEffct hsa-miR-483-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-40 1.85E-36 1.15E-39 1.06E-38 106 623 "KDM5D,NDRG3,CC2D2A,OGT,UPRT,ARRB2,NUMB,ATP1B3,SLC2A11,AZGP1,DDR1,RUNX1T1,METTL6,CLCN3,QKI,LY86,RCHY1,ENTPD4,SNCAIP,CSNK1G3,RIMS2,DCAF4,BOC,DCAF8,YTHDC1,FAM78B,E2F6,AASDH,SNX29,FSD1L,FAM13A,STX2,NSRP1,SLC9B2,FHL1,RGPD5,ABLIM2,GABRG2,RAPGEF6,KIAA1841,GGTA1P,RUNDC3A,ZNF638,GPD2,PRUNE2,TDRKH,CCDC184,GRIA2,GUCY1B1,SCIN,KCNN2,KCNN3,SYTL4,MAT2A,MIA2,NEFH,SMIM11A,NTRK3,CCDC144B,RASGEF1B,SAMD9,PTN,TTC13,SH3TC2,RASGRF2,RBBP6,PNMA8A,ELP2,RPE,ZNF568,SATB1,CPEB3,SLC6A8,SLC9A5,SLC22A4,SMARCC2,INTS9,RCOR3,LIMCH1,SOX3,UHRF1BP1L,RBM26,PBLD,PHLDB1,ZEB1,NAT16,ARHGAP9,FRYL,THRA,ERCC6L2,R3HDM1,C9orf85,SYNPO2,TSN,UBTF,VLDLR,XPO1,LGI4,ZNF154,STOX2,RNF103,UBE3B,FBXO36,MSRB3,GAN,SPATA13" MicroRNA hsa-miR-140-3p.1:TargetScan hsa-miR-140-3p.1 TargetScan 3.45E-40 1.93E-36 1.20E-39 1.10E-38 93 480 "PTCHD1,KCTD16,PCDH10,ARRB1,CCDC74A,LDLRAD4,CABP7,HAP1,CAMK2G,CCNT1,LRRFIP1,NDST3,CLTC,RCHY1,NSL1,CLOCK,LRIG1,PLXNA4,CCDC144A,MATR3,ELMSAN1,ELMO1,GRIN3A,HS3ST2,CPEB2,DRP2,RCAN1,FAM78B,DNM1L,PLXNC1,EZH1,FCGRT,FGF13,ANKFY1,CELF1,GHR,RAB30,GRM2,KAT7,DDX19B,ELOVL5,HMGCR,HSF2,IL6ST,KIF2A,KIF5A,NCOA7,CHIC1,MEF2C,MEIS2,KCTD6,MGAT3,DBNL,MXI1,NBL1,NF1,NOVA1,PDE3A,PDPK1,PIK3R1,KCTD15,POLR2F,PPP2R5E,KANSL1,PRKAB2,PRKCB,PTCH1,RAD51D,KHDRBS2,REV3L,GTDC1,SATB1,CASC3,BTBD7,ATF7IP,EPC1,KDM3A,GLT8D1,PEG10,DDN,POGZ,ANKRD12,FBXW11,SATB2,AP4E1,RGMB,NR2C2,RUSC1,ANKS1B,CADM2,NAV3,RTN4,GAN" MicroRNA hsa-miR-3190-3p:mirSVR_highEffct hsa-miR-3190-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.57E-40 2.00E-36 1.24E-39 1.14E-38 124 841 "RALGAPA1,KLHL32,ADD1,ADD2,MTUS1,KIAA1324,C1QTNF3,OGT,DPP10,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,USP37,NUMB,INSYN2B,TMEM108,ATP1B3,ZNF583,N4BP2L1,DPY19L3,ARHGEF7,CALM1,METTL6,LRBA,ZMYM4,SRSF11,TPP1,ARMC8,ABI3BP,ZFP28,CPS1,FAM171B,CSF1,SOCS5,BOC,DOCK4,DAPK1,AIF1L,PITPNC1,FAM107B,CHRDL1,DTNB,E2F6,PHC2,FRY,EPB41,RABEPK,IGSF6,FCGR1A,FDFT1,GORAB,POLR1B,SUCO,UFM1,STAMBP,ERGIC3,NSG1,MEGF11,TNRC6A,KDM2B,PRUNE2,GPER1,PCLO,KAT7,NCKAP1L,SHISA6,SMAP1,IL6ST,INPP1,KCND1,KIF5A,KIT,PAXBP1,SYTL4,MATN2,MBD1,BLOC1S2,ZC3H12B,NF1,DNHD1,NPR2,P2RX7,ZNF827,PFKFB2,ZNF655,PKM,SMIM7,PURG,PMP22,PILRA,GDPD2,RASGRF2,TRIM68,RNASEL,ZNF532,EXD2,CARF,MRAP2,ARMH4,MCMBP,TCP11L1,KCNIP1,PEAR1,CASC3,COPZ1,FNDC3A,TTC17,VPS13A,DMXL2,CUX2,USP32P1,TIAM1,C9orf85,XPO1,LYPD6,STOX2,WNK3,AMN1,FZD3,MARCH8,RTN4,PHTF2,KLHDC1,PRRT4" MicroRNA hsa-miR-593:mirSVR_highEffct hsa-miR-593:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.57E-40 2.00E-36 1.24E-39 1.14E-38 124 841 "ELFN2,BEND6,ZNF608,PCDH19,WDR35,ALK,DPP10,APOC1,DYNLL1,ATP2A2,ADAM23,ADAM15,NRP2,THSD7A,KALRN,CAST,CD86,NOG,SRSF11,HECTD1,AKAP6,CREM,CLIP3,MROH8,SEC24C,ARHGEF10,SUSD5,PDE4DIP,UBXN2A,RIPOR2,EARS2,RASSF2,DGKG,DAPK1,SGSM2,EXOG,DTNA,HIPK3,FCF1,EGR3,EPB41,RCAN2,EPHB1,ERBB2,MRPL37,EYA1,STRADA,KAT8,FGF11,FOLH1,SMC2,USP21,KHDRBS3,ST6GALNAC3,CPLX2,KIAA1841,LUZP2,DCLK2,ATP2B1-AS1,MSL1,MYLK2,INPP5B,LRRTM1,MAN2A2,MEIS1,BLOC1S2,PTOV1,NTRK3,NUCB2,ZNF827,CDK18,ABCB1,ZNF655,SMIM7,PRIMPOL,MAPKAP1,SEPT4,CNTLN,FAM66C,SETD5,GSTCD,KCNIP1,S100B,ZFP2,SCAF8,SHC4,CHD9,CNKSR2,WDR47,BTBD7,SLC22A4,ZFP1,MYH15,MBD5,BDP1,SP4,TSPYL2,PBLD,SSTR1,ERBIN,STAC2,NSFL1C,KLHL7,ASTN2,CAMTA1,SATB2,TCF12,SZT2,ARHGAP9,FRYL,CYB561A3,ITGB3BP,ASXL3,ERCC6L2,FAM124A,AMACR,KCNE5,XRCC4,KCNT2,ZNF74,FIP1L1,AMN1,KAT6A,RNF170" MicroRNA hsa-miR-135a:PITA hsa-miR-135a:PITA_TOP PITA 3.58E-40 2.00E-36 1.24E-39 1.14E-38 90 449 "INTS2,MTUS1,OSBPL8,ALCAM,TRMT9B,APC,GAS7,ZFYVE28,ARNTL,PDE8B,NCOA1,ATP2B2,ARHGEF7,KALRN,PTBP2,LDB2,ARHGEF2,KCNAB3,DLGAP2,FOXN3,ARHGEF6,PCYT1B,ZNF385A,CSNK1G3,SLITRK5,ARHGEF4,RIMS2,HDAC4,LONRF1,JAKMIP2,MYEF2,RAB39B,HIPK3,GOLGA7,EPB41,ERBB4,EXTL2,EYA1,SYT3,NBEA,FUT9,B4GALNT1,CPLX2,CPLX1,GHR,FERMT2,PSIP1,MIER3,NEGR1,KCND1,MAT2A,MEF2C,MEIS2,NEFM,NF1,NPTX1,GPR85,DRAM2,CEP41,DIRAS2,SNRK,ELOVL2,PTK2,PTPRD,RAP1GDS1,SETD5,PCMTD2,PPM1E,TEX2,RGL1,KANK1,PLCB1,CAMTA1,CUX2,SIRT1,SLC44A1,TIAM1,MTMR14,TMEM9,KAT6B,VLDLR,TMEM237,ZFAND5,EVI5,ADAMTS9,ST7,HNRNPA3,PHTF2,MSRB3,SOCS4" MicroRNA hsa-miR-135b:PITA hsa-miR-135b:PITA_TOP PITA 3.58E-40 2.00E-36 1.24E-39 1.14E-38 90 449 "INTS2,MTUS1,OSBPL8,ALCAM,TRMT9B,APC,GAS7,ZFYVE28,ARNTL,PDE8B,NCOA1,ATP2B2,ARHGEF7,KALRN,PTBP2,LDB2,ARHGEF2,KCNAB3,DLGAP2,FOXN3,ARHGEF6,PCYT1B,ZNF385A,CSNK1G3,SLITRK5,ARHGEF4,RIMS2,HDAC4,LONRF1,JAKMIP2,MYEF2,RAB39B,HIPK3,GOLGA7,EPB41,ERBB4,EXTL2,EYA1,SYT3,NBEA,FUT9,B4GALNT1,CPLX2,CPLX1,GHR,FERMT2,PSIP1,MIER3,NEGR1,KCND1,MAT2A,MEF2C,MEIS2,NEFM,NF1,NPTX1,GPR85,DRAM2,CEP41,DIRAS2,SNRK,ELOVL2,PTK2,PTPRD,RAP1GDS1,SETD5,PCMTD2,PPM1E,TEX2,RGL1,KANK1,PLCB1,CAMTA1,CUX2,SIRT1,SLC44A1,TIAM1,MTMR14,TMEM9,KAT6B,VLDLR,TMEM237,ZFAND5,EVI5,ADAMTS9,ST7,HNRNPA3,PHTF2,MSRB3,SOCS4" MicroRNA hsa-miR-4274:mirSVR_highEffct hsa-miR-4274:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.69E-40 2.07E-36 1.28E-39 1.17E-38 100 556 "BEND6,UPRT,RGS20,SLC4A4,VXN,RAB28,TPP1,C4orf33,QKI,CNTN1,ARMC8,LETMD1,ABI3BP,BAG4,ZFP28,CLOCK,AKAP12,HAPLN1,TRIM69,ARHGEF10,SIPA1L1,VCAN,SOCS5,DOCK4,TCAF1,DCAF8,PITPNC1,DNM1,USP3,CDON,FCF1,MRO,RABEPK,FCGRT,STRADA,FGF11,FGFR3,PRKAG2,CAMKK2,CELF1,TPPP3,GABBR1,CHL1,GALNT15,USP19,GLUL,DCLK2,GNAO1,GRIA2,PSIP1,ELOVL5,LRRC75A,GAREM2,NIM1K,SCIN,KCNH2,STMN1,NCOA7,PACRG,MARK3,MAT2A,MEIS1,MEST,PCDH9,XRN1,ING3,PIGG,CNTLN,PTH1R,CEP97,TMEM255A,ENOX1,REV3L,HSD11B1L,ZNF331,ATXN2,TRA2B,FRMPD1,CNKSR2,BTBD3,SNRPN,BDP1,GLT8D1,RBM26,PHLDB1,VPS13A,ANKRD28,TACC1,ALG1,DMXL2,SZT2,SYNPO2,SMUG1,RUNDC3B,SSBP2,ANKS1B,VPS35L,FZD3,KLHDC1,GAN" MicroRNA hsa-miR-142-3p.2:TargetScan hsa-miR-142-3p.2 TargetScan 3.86E-40 2.16E-36 1.33E-39 1.23E-38 88 429 "PTCHD1,ADRB2,HECW2,ALCAM,ANK2,MAP4K3,APBB2,APC,IGDCC4,CASK,NUMB,ATP2A2,ATP2B2,RUNX1T1,ARHGEF2,DCLK1,MAGI1,CFL2,CLTC,QKI,MAP4K4,CNN3,CLOCK,C2CD2,OSBPL3,CSNK1G3,PUM1,MAML1,BRINP1,ELMSAN1,JAKMIP2,CPEB2,PDCD6IP,PLXNC1,KCTD3,EIF5,ETV1,FOXO3,CELF1,FUT9,PCDH17,PPARGC1A,PRRC2B,NEGR1,RBPJ,ITPKB,KCNN2,CHIC1,MEIS1,NOVA1,GPR137C,NLGN3,PIK3C2A,PLCL1,PLEC,PPP2R5E,FITM2,QRICH1,PTPN13,MARCH1,KHDRBS2,RDX,RFX3,KLHL11,RIC8B,MRAS,HSPA4L,FBXO11,CCDC88A,BTBD7,CPEB4,PDZD2,ERC1,CDK19,NFASC,DIP2A,PHLDB1,ANKRD28,CRTC1,GPRIN3,LRRC8A,MTCH1,KLC2,RICTOR,ANKS1B,CADM2,EVI5,FXR1" MicroRNA hsa-miR-205-5p:TargetScan hsa-miR-205-5p TargetScan 3.92E-40 2.19E-36 1.35E-39 1.25E-38 87 419 "RNF157,AXIN2,PTCHD1,ABCD2,ANK2,PI16,APBB2,ARRB2,NCOA1,CALM1,CCNT1,MAGI1,CFL2,CHN1,B4GALT6,CLTC,QKI,ARMC8,COX4I1,RTTN,CDC42BPB,PREPL,CRMP1,CSF1,CTH,ARHGAP24,ELMSAN1,CPEB2,KRBA2,PHC2,HIPK3,CNNM1,FSD1L,CALCRL,EPB41,RAB9B,ERBB4,FGF14,DBF4,CBX1,KCNMB4,KAT7,MIER3,NKD1,IL6ST,KCNB1,LSAMP,CHIC1,MXI1,NFIX,NRCAM,CLDN11,P2RY1,PFKFB3,PLCL1,MTRF1L,PURG,EPB41L4B,MAPK3,GRAMD1C,BCAS3,PTPRD,PTPRG,GTDC1,LRRK2,AP1AR,BTBD3,LIMS2,CDK19,MPRIP,NSFL1C,PLCB1,FAM208A,MGRN1,SATB2,CUX2,ITGB3BP,NACC2,FAM155A,RBFOX3,PCDH20,MICU3,LYPD6,GDPD5,ADAMTS9,FZD3,RNF146" MicroRNA hsa-miR-1252:PITA hsa-miR-1252:PITA_TOP PITA 4.91E-40 2.75E-36 1.69E-39 1.56E-38 82 371 "XKR4,PWWP2A,HECW2,OSBPL8,SEMA6A,SPOP,MAGEE2,PPFIA3,CADPS,NCOA1,BCL7A,FUBP1,FOXN3,NRXN3,CNTN1,AKAP6,MAGED1,CRY2,SLITRK5,HDAC4,ZC3H11A,POM121,DPYSL2,DUSP9,EIF4G2,PAN3,RCAN2,FGF12,NBEA,GABRB3,IP6K3,C15orf41,ARFIP1,PCDH17,GHR,TTBK1,RNF165,MAP4K5,SMAD1,MAP2,MAT2A,MBNL1,MITF,MYCN,NBL1,PDE4B,STRN3,MINDY2,PPP1R1A,CNTLN,RIC8B,PBRM1,SETD5,SGK1,KIF21A,CPEB3,CHD9,FBXO11,DOK5,ZNF423,SPTB,CDK19,POGZ,CAMTA1,MCF2L,ADGRL3,TBL1X,TCF4,RPGRIP1L,TCF12,DICER1,SIRT1,FAM155A,XPO1,ZIC1,ZIC2,REEP1,POLR3H,SMARCAD1,RGS7BP,PHTF2,SOCS4" MicroRNA hsa-miR-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.18E-40 2.90E-36 1.78E-39 1.64E-38 130 921 "ACTN1,FMNL2,PI16,ATP6V0A1,SEC11C,HCN2,BMP7,FUBP1,AP1M1,CACNA2D1,CALM1,PTBP2,CAMK2G,CAST,RGN,CDH2,LRWD1,CLCN3,CLTC,CNN3,BAG4,CDC42BPB,RBM39,AKAP12,RIMS4,PLXNA4,RIMS2,HDAC4,MATR3,IST1,DBN1,YTHDC1,MYEF2,KLHL3,ZC3H11A,GSDME,POM121,SEC16A,RAB39B,E2F5,EDN1,HIPK3,EGFR,GOLGA7,EIF4G1,RGS17,MFSD10,EPB41L2,COQ7,RABEPK,SRRM1,IP6K2,SEMA4D,FLNC,ANKFY1,NELFCD,ZBED3,STAMBP,FYB1,MTHFD2,GLI2,RAB30,ZNF638,KDM2B,FERMT2,GPD2,RABL2A,PSIP1,MAN1B1,DDX19B,IGF1,KCND1,KIF2A,L1CAM,LIFR,LIMS1,PAXBP1,MOV10,NBL1,CHAMP1,OXTR,GPR137C,ABCB1,PSAT1,EPB41L4B,PTPRD,SH3TC2,PRIMA1,C12orf49,ZNF568,TRA2B,COPZ1,FAM102A,MYO18A,FNDC3A,FAM81A,PPP4R3A,SLC8A1,TTC17,TMCC1,USP33,TROVE2,LARP4,NXT2,MPRIP,SYNE2,SYPL1,FAM208A,TRIM2,SYNE1,HIF3A,SLC44A1,CBX5,TLR4,LRRC8A,TPM1,TPM2,WBP2,DOK6,TRPS1,SGK3,UBTF,UGT8,PLEKHH2,TRIM9,AMZ1,FTSJ1,HPS4,HNRNPA3,NETO2" MicroRNA hsa-miR-1308:mirSVR_highEffct hsa-miR-1308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.87E-40 3.28E-36 2.02E-39 1.86E-38 101 570 "ABHD6,RNF150,SLC24A4,MTUS1,PCDH19,WDR35,OSBPL8,C1QTNF3,USP35,ABCD2,LCORL,SUGT1P4-STRA6LP-CCDC180,PPFIA3,TMEFF1,ZFYVE28,NCOA1,MPDZ,FUBP1,CAST,SLC16A4,CCPG1,PLEKHB1,NDST3,PPT2,CNGA3,SUMF2,LETMD1,AKAP12,GDA,CSF2RA,DZIP3,ERC2,FAM107B,CPEB2,DPYSL2,FAM13A,SPEG,ACSL4,POLK,C2orf88,SMC2,PRELID3A,ST6GALNAC3,GALC,RAPGEF6,KIAA1841,PPARGC1A,RAB30,LOXL3,PLPP7,IDH3B,TTYH2,KITLG,MITF,XRRA1,ADAM22,MYCN,TCEAL5,NFE2L2,NTRK3,NUCB2,CNTN3,PCSK5,NLGN3,PIK3C2A,KCTD15,SLC25A23,PPARA,MAPK10,CNNM2,VPS13C,PTPRB,TMEM231,MARCH1,TRIM68,SETD5,ROBO2,ZNF568,SEMA6D,CHD9,FNDC3A,FHOD3,BTBD3,CCDC88A,MBD5,TEX2,ZC3H13,PBLD,ZSCAN29,ADAMTS17,TAL1,RPGRIP1L,TK2,NR2E1,FAM47E,RGS7BP,FAM13C,SMIM8,FBXO36,CASC15,ADAMTSL3" MicroRNA hsa-miR-598:mirSVR_lowEffct hsa-miR-598:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.56E-40 4.23E-36 2.60E-39 2.40E-38 90 453 "SYS1,HFM1,SEMA6A,SUGT1P4-STRA6LP-CCDC180,PPFIA3,MARCH3,RASL11B,SLC2A11,DPY19L3,TTLL9,JAZF1,CAMK2A,RAB33A,FAM149A,ABI3BP,PDE4DIP,DOCK4,ZNF804A,MFAP3L,WDR20,NR1D2,DOCK2,DTNA,RASGRP1,EIF5,TUBD1,LRRC17,RABEPK,MRPL37,ETV1,POLK,IP6K2,EVL,SLC37A3,PDLIM5,ERAP1,RAB30,STARD3,PRRC2B,BTN2A1,GUCY1A1,ATOH8,MIER3,ICA1,LRRCC1,ITGAM,MAP2,MARK3,MEIS2,MEST,XRRA1,ADAM22,MYCN,CNOT4,POLR2F,PPP2R5E,RASGEF1B,PKIA,WBP1L,STK32A,RAD51D,ZFHX4,CARF,ELP2,ADAL,HSD11B1L,TRAPPC13,SCP2,SEC14L1,RADIL,SLC12A2,SLC12A4,CABCOCO1,FNBP1,KDM3A,KDM4C,CDK19,SYN1,KLHL4,PMS2CL,TMEM9,UBE2H,VLDLR,GUSBP1,ZNF138,INTS3,ADAMTS9,SIGLEC10,PDSS2,JMJD1C" MicroRNA hsa-miR-454*:mirSVR_lowEffct hsa-miR-454*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.30E-40 4.65E-36 2.86E-39 2.63E-38 121 810 "ASIC1,KDM5D,XKR4,CCDC85A,BEND6,AP2A2,SPOP,UNC79,MAP4K3,ASGR1,STK33,NUMB,ATP1B3,N4BP2L1,RIPK1,BBS2,DNAJC27-AS1,KSR1,FUBP1,MYRF,LDLRAD4,CA8,PTBP2,CCPG1,CFL2,COX4I1,NRG2,GDA,SEC24C,CST3,DCAF8,KCTD8,MAML1,KIAA0319,RAB39B,RCAN1,ECM2,PHF20L1,GOLGA7,KCTD3,PLEKHA1,MRPL37,MRPL10,ETV1,ANKMY1,RGPD5,ATP13A4,ERGIC3,AP4B1,DISC1,KIAA1841,ZNF638,STON1,GPR37,STMN2,RABL2A,ZHX1,SYNPO,SCIN,KLHL23,LIFR,SMAD9,TM6SF1,MEF2C,MEIS1,MYO9A,P2RY13,NCAM2,NOVA1,PCSK5,PDE4B,PFKFB3,SNX10,MTRF1L,HYDIN,MASP1,PTPN13,OXR1,RBBP6,ZDHHC14,RET,GSTCD,BAALC,GLDN,LRRK2,ABCA11P,GALNT10,KIF21A,ST6GAL1,ANKRD36,SNAP25,MAPKBP1,MBD5,SNRPN,NMNAT2,PEG10,VPS13A,PLCB1,SYP,CAMTA1,ATMIN,TRIM2,SZT2,DOCK9,TMEM9,TPM1,SSBP2,PLEKHH2,WRN,RICTOR,ZNF28,SPHK2,CELF4,REEP1,DPYSL5,UPF3A,SLC30A4,EVI5,RNF103,GAL3ST3,JMJD1C" MicroRNA hsa-miR-410:PITA hsa-miR-410:PITA_TOP PITA 8.55E-40 4.79E-36 2.94E-39 2.71E-38 81 364 "ACTN1,FMNL2,ELFN2,PARG,CASK,NUMB,ATP2B2,JAZF1,CALB1,PTBP2,CLDN10,SRSF11,NRXN3,FAM19A5,CNR1,RCHY1,MYRIP,PLCXD3,ARHGAP24,MATR3,IP6K1,RHOBTB1,SACS,DMD,DYNC1I1,DPYSL2,YAF2,ERBB4,STAU2,MSTN,ARFIP1,PCDH17,FERMT2,GRIA2,MAP4K5,AGFG1,SOWAHA,IGF1,NKD1,IL12A,ITPKB,MAP2,LRP1B,SCAMP5,MKLN1,NEXMIF,NF1,NFE2L2,PCDH8,EPB41L4B,PPP3CA,PTCH1,MTMR10,PTX3,RDX,PBRM1,CARF,RORB,CPEB3,CHD9,CPEB4,ANKFN1,PDZD2,SP4,SYN2,SYPL1,ANKRD12,FBXW11,TCF4,TRIM2,TCF12,DOCK9,SLC35G2,TIAM1,PDSS1,VSNL1,ZIC1,RTN4,KAT6A,PHTF2,SOCS4" MicroRNA hsa-let-7c:mirSVR_highEffct hsa-let-7c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.84E-40 4.95E-36 3.04E-39 2.80E-38 120 798 "KLHL32,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CHN2,TAOK2,NDST3,C7orf61,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,OSBPL3,PDE4DIP,DAPK1,B3GAT3,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,PPP1R1B,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,CNTRL,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,FAM69A,NME9,MEIS2,CNOT4,NOVA1,OGG1,FAM218A,XRN1,POLR2F,PKIA,GDPD1,MASP1,BDNF-AS,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,ATXN7,FNIP1,KIF27,FNDC3A,BDP1,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCEA1,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,RICTOR,LYPD6,SMARCAD1,STOX2,PHTF2,GAN" MicroRNA hsa-let-7i:mirSVR_highEffct hsa-let-7i:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.36E-40 5.24E-36 3.22E-39 2.96E-38 119 786 "KLHL32,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CALB2,CHN2,TAOK2,NDST3,PPT2,QKI,MAP4K4,AHCTF1,IGDCC3,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,DISC1,GATM,CYP46A1,POLL,CNTRL,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,NKD1,ZNF678,FAM69A,NME9,KPNA5,MEIS2,CNOT4,NOVA1,OGG1,XRN1,EPB41L4B,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS3,RGS12,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,CLIP1,ATXN7,FNIP1,KIF27,FNDC3A,TET1,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,CDH22,MTMR14,FAM124A,TPM2,PDSS1,RICTOR,LYPD6,SMARCAD1,CADM2,STOX2,WNK3,PHTF2,GAN" MicroRNA hsa-miR-1193:mirSVR_highEffct hsa-miR-1193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.73E-40 5.45E-36 3.34E-39 3.08E-38 100 562 "SYN3,PWWP2A,ADGRF5,ARHGAP20,VAT1L,PPFIA3,ARHGDIA,ATP1A1,LINC00847,SYNJ2,LDB2,SRSF11,CHN2,PLEKHB1,LETMD1,CSF1,CYBB,ZNF337,MYEF2,FBXL5,ZC3H11A,SEC16A,ZNF582-AS1,NR1D2,CNNM1,MBNL2,EIF4G2,RABEPK,EXTL2,CORO2B,POLR1B,ST6GALNAC3,RAPGEF6,TUBGCP4,MSTN,SPIN1,GLUL,ZNF638,GPD2,PCLO,ATP2B1-AS1,CIT,RNF165,MAN1B1,HNMT,HSPA1L,SHISA6,SMAP1,RBPJ,KIT,KPNA5,MAN2A2,MEIS2,ZNF680,VWA2,LOC100128398,PDE4D,PDE1B,NLE1,FXYD1,TATDN3,GRAMD1C,VPS13C,PTK2,PTPRD,PTPRO,KCTD17,SETD5,ADAL,LRRK2,LRFN5,SCN8A,CHD9,KDM4D,SEPHS1,SLC8A1,BTBD7,TET1,ANKRD36,CMTR2,NMNAT2,DBNDD2,ATP10B,NKAIN2,CAMTA1,SMG6,SYNE1,FAM200B,ICAM5,ERCC6L2,TPM2,PDSS1,SSBP2,RPL7L1,TBC1D15,MEIS3,EMSY,CADM2,PRDM10,LAS1L" MicroRNA hsa-miR-495-3p:TargetScan hsa-miR-495-3p TargetScan 1.03E-39 5.74E-36 3.52E-39 3.24E-38 105 619 "RNF150,PTCHD1,KCTD16,KIAA1324,OSBPL8,C1QTNF3,ARHGAP20,PCDH10,DPP10,APC,PDE8B,NCOA1,ATP2B2,BMP7,FUBP1,LDLRAD4,CACNA2D1,CAMK2G,CAST,CBFA2T2,CDH2,DLGAP2,LHX2,NRXN3,CNR1,SEC31B,CLOCK,IPCEF1,RIMS4,PLXNA4,PITPNM3,PLCXD3,CCDC144A,PYGO1,BRINP1,DBI,DMD,DRP2,KLHL5,CELSR3,MBNL2,AASS,RGS17,COQ7,ERBB4,CEP85L,AMOTL2,PDLIM5,CELF1,RAPGEF6,IP6K3,KDM2B,GPD1,DIDO1,HMGCR,NEGR1,AGFG1,IGF1,C2CD4C,KCNN3,MSI1,MYO9A,MYT1,PCDH8,PDE3A,FAM216A,PLCL1,PPP2R2C,KANSL1,MAPK10,PTPRG,KLHL11,ROBO1,RORB,MCMBP,SATB1,SCN8A,HSPA4L,FBXO11,R3HDM2,CCDC92,CCDC88A,INTS9,FAM126B,FNBP1,CLSTN2,MPRIP,RHBDL3,ARC,MCF2L,RPGRIP1L,CLASP1,DICER1,AP4E1,NACC2,CBX5,ASXL3,RASD2,RICTOR,MFF,FXR1,NETO2,NETO1,GAN,CPNE4" MicroRNA hsa-miR-579:PITA hsa-miR-579:PITA_TOP PITA 1.22E-39 6.84E-36 4.19E-39 3.86E-38 88 435 "GPRASP2,OGT,DPP10,PKP4,APAF1,APC,TMEFF1,CADPS,MARCH3,ZBTB10,PROM1,CACNB4,CALB1,CALM1,B4GALT6,MAP4K4,CNR1,AKAP7,AHCTF1,NSL1,RBM39,APPL1,DOCK4,KIF26A,LONRF1,TIAM2,FAM107B,DMD,TENM1,EPB41L2,GPHN,ERBB4,ETV1,FOXO3,AFF2,NBEA,ATP2C1,MEGF10,IQGAP2,PCDH17,PPARGC1A,DHRS4,MAP4K5,HAS2,DDX19B,BACH2,AGFG1,SMAP1,LIMS1,SMAD1,MAPT,MITF,ZC3H12B,NOVA1,PDE4D,ZNF655,STRN3,PTPRD,TMEM255A,REV3L,FIGN,SLC25A36,ZFHX4,SETD5,ROBO1,SEMA6D,FNDC3A,NLGN1,WDR37,FAM81A,CPEB4,MYCBP2,ERBIN,ELOVL4,TTBK2,SYPL1,TCF4,DMXL2,SIRT1,THRA,TRPS1,UBE3A,GORASP1,ZIC1,INTS3,CADM2,PRDM10,HNRNPA3" MicroRNA hsa-miR-378*:mirSVR_highEffct hsa-miR-378*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-39 6.94E-36 4.25E-39 3.91E-38 102 586 "WDR35,CC2D2A,ZNF578,AMT,ATP1B3,BACH1,ADGRB3,ZNF599,DST,KALRN,ZNF501,RAB33A,RAB28,SUMF2,ZFP28,GDA,RGS6,CSF2RA,DZIP3,PHF14,CCDC144A,GPRASP1,ARHGAP32,DDX46,EXOG,NYAP1,DNAH9,DTNA,ANKRD46,RASA4,EPHB1,ENPP6,MRPL37,F8,TMEM132C,TAOK3,FCGR1A,STAMBP,CAMKK2,ATP2C1,AP4B1,B4GALNT1,ZNF559,SRCAP,TCERG1,DBF4,LOXL3,LNX1,GPR12,DHX35,SMAP1,EID2B,ZNF678,KIF5A,SYTL4,PPM1L,MMP16,LYRM9,OPA1,PDE1C,PCDH18,TRHDE,LRP12,EPB41L4B,DCHS2,PTK2,PTPRN,PTPRN2,FAM66C,SH3TC2,SLC25A36,CARF,ROBO2,PCMTD2,SPIN3,TCP11L1,ABCA11P,TRAPPC13,ATXN2,SUPT20H,COPZ1,NLGN1,WDR47,CCDC88A,KBTBD4,PDZRN3,SOX3,BDP1,ZC3H13,LMO3,SULF2,SMG6,DMXL2,ERCC6L2,UBE2H,UGT8,WIPF1,ZNF781,FTSJ1,EMSY,PRDM10,HNRNPA3" MicroRNA hsa-miR-491-5p:mirSVR_highEffct hsa-miR-491-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-39 7.16E-36 4.38E-39 4.03E-38 114 727 "ABCF1,ASIC1,GALNT16,PTCHD1,PCDH19,SPOP,AMPD3,LRFN1,PI16,PHF12,LGR5,SEMA4G,CDK13,ZBTB10,ATP2B2,MPDZ,KALRN,CBR1,KYAT1,MTMR7,ZMYM4,ARHGAP33,TIGD7,PLEKHB1,PPT2,TPP1,ABCG2,IQCK,GREB1,PUM1,GAPVD1,CENPL,GIT2,DDX46,RHOBTB1,KIF19,GRIN3A,EDN3,PHC2,FRY,C3orf18,TMEM35A,SIRPB1,PCYOX1,EVL,ZNF605,PRELID3A,SEPT9,INPP5K,ARFIP1,ZNF276,COPS8,TNRC6A,TDRKH,KAT7,IDH3A,ZNF546,RBPJ,NME9,LAMP2,MAT2A,MEIS2,GIT1,NF1,IGSF11,OGG1,PCSK5,CDK18,PFKFB2,FAM218A,MAPKAP1,SH3KBP1,PKIA,HYDIN,RASGRF1,MRAP2,ABCA11P,DGLUCY,COPZ1,SH3GL3,FAM214B,NAPB,ATF7IP,SMARCC2,SMARCD3,FNBP1,IQSEC2,DDN,NFASC,ATP10B,SUPT5H,SYT1,NAT16,ARHGAP9,CCDC173,SLC44A1,GALNT17,RGMB,RUNDC3B,TTC3,OSBP2,PLEKHH2,CLDND1,RICTOR,KCNT2,MKRN3,ZSCAN26,DNALI1,GAL3ST3,KCNAB1,NELFE,ST7,RNF170,CPNE4" MicroRNA hsa-miR-4270:mirSVR_highEffct hsa-miR-4270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-39 7.46E-36 4.56E-39 4.20E-38 123 839 "CLK4,BRAP,KIAA1211,PTCHD1,LRFN2,KIAA1324,SRPX,LRFN1,OGT,SUGT1P4-STRA6LP-CCDC180,PARG,CFLAR,LURAP1,RUNX1T1,ENTPD6,MAGI1,PPT2,TPP1,FBXO7,QKI,LY86,CNTFR,SUMF2,MYRIP,ZNF385A,CRYM,PHF14,RIMS2,DCAF8,TMCC2,ZNF582-AS1,HS3ST2,NR1D2,DPP6,ABCC5,ANKRD46,C8orf37,EPHB1,DENND4A,VPS26C,PRMT5,ZNF589,NOP56,NELFCD,CGREF1,AP4B1,GABRG2,IGSF5,TUBA8,GHR,PPARGC1A,STARD3,CBX1,MAP7D2,GNAL,FUT10,CCDC184,LPAR4,RABL2A,SOX21,HNMT,MSL1,FAM95B1,LRRC25,RBPJ,PAXBP1,SYTL4,NCOA7,MAT2A,MBD1,PPM1L,BEX5,NBL1,NOVA1,NTRK3,CDK18,FAM98B,PCDH18,EXOSC10,SEPT4,PPP1R1A,KLK6,GDPD2,TMEM260,RAP1GDS1,TRIM68,PRRT2,RIC8B,SETD5,CARF,CYB561D1,NEK11,FBXW7,ZNF331,LRFN5,PEAR1,CASC3,PKNOX2,CCDC88A,ELMO2,SNAP25,SP2,SPP1,VPS13A,SYN2,MLST8,SATB2,ZEB1,AKTIP,SLC44A1,MTMR14,ERCC6L2,NEIL2,TSN,SSBP2,FLRT2,LAMP5,EMSY,HPS4,DOCK8,FBXO36,DPF3,LAS1L" MicroRNA "GTACTGT,MIR-101:MSigDB" "GTACTGT,MIR-101:MSigDB" MSigDB 1.54E-39 8.59E-36 5.25E-39 4.83E-38 67 242 "ASIC1,ADCY6,SPOP,UNC79,OGT,PPFIA4,TMEFF1,KIF1A,MTMR2,USP6,CBFA2T2,C1orf52,MAGI1,CLCN3,QKI,MYRIP,SOCS5,LONRF1,CPEB2,ABCC5,PHF20L1,EYA1,KHDRBS3,DOT1L,KAT7,FAM222A,HAS2,NEGR1,PACRG,MARK1,MBNL1,MYCN,NACA,NOVA1,PCDH8,PDE4A,PDE4D,GPR85,PLXNB1,PURG,ING3,LRRN3,USP47,REV3L,UBR7,NUDT11,ZFHX4,ZNF532,ROBO2,FBXW7,CPEB3,ABLIM3,BTBD3,SOX11,POGZ,ERBIN,CAMTA1,TAL1,FBXW11,PUM2,RASD2,FLRT2,ZNF24,EMSY,MPPE1,ADAMTSL3,ADAMTS10" MicroRNA hsa-miR-96:PITA hsa-miR-96:PITA_TOP PITA 1.84E-39 1.03E-35 6.29E-39 5.80E-38 80 358 "XKR4,ADCY6,SLC24A4,SEMA6A,ALK,OGT,LRCH2,C6orf89,DPY19L3,ADGRB3,MTMR3,JAZF1,CACNA1G,LDLRAD4,CACNB4,THSD7A,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,CLTC,MAP4K4,CNN3,CABP1,MYRIP,CDC42BPB,LRIG1,RIMS4,ERC2,ARHGAP24,TM9SF4,E2F5,SNX29,EIF5,GPHN,FOXF2,FAM49B,ST6GALNAC3,FYN,B4GALNT1,PCDH17,SPIN1,ZHX1,MBNL1,CHIC1,MITF,NEXMIF,NOVA1,NPTX2,IGSF11,GPR85,PIK3C2A,EPB41L4B,SH3KBP1,ZFHX4,MCMBP,MRAS,FAM81A,PPP4R3A,BTBD3,CPEB4,MYO16,SS18,KLHL7,COBL,TACC1,CAMTA1,FBXW11,TBL1X,TCF4,SIN3B,ZIC2,TRIM9,TMEM198,ZFAND5,NAV3,ST7,JMJD1C,GAN" MicroRNA hsa-miR-3115:mirSVR_highEffct hsa-miR-3115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-39 1.04E-35 6.37E-39 5.87E-38 105 623 "CLK4,C3orf14,BRAP,HECW2,KLHL13,KCTD16,RTL9,SRPX,APBA2,ZSCAN18,CCAR2,ADAM23,TTLL9,SEC11C,DST,SCAPER,CA8,KALRN,ZMYM4,RCBTB2,CHN1,B4GALT6,FAM19A5,AHCTF1,GDA,ARHGEF10,VAC14-AS1,PDE4DIP,KIAA0408,HDAC9,KATNAL2,DGKB,KIAA0753,RHOBTB1,SNAP91,MED12,CPEB2,DMTF1,DPH1,PDCD6IP,GOLT1B,EDNRA,FCF1,RASGRP1,CALCRL,SLC9B2,FGF14,ST6GALNAC3,AP4B1,KCNMB4,ZNF782,WDFY3-AS2,TDRKH,GUCY1B1,HLF,HNMT,NEGR1,CELF5,EID2B,FAM95B1,SLC6A17,JAK2,KCND2,LIFR,LIMS1,NCOA7,CHIC1,NF1,PCSK5,PDE1C,FAM218A,C19orf57,RASGEF1B,SNRK,RAP1GDS1,TRIM68,ERI2,RFX3,ATXN2,DZIP1,FAM81A,DHX30,CCDC88A,RCOR3,TMCC1,ZC3H13,DDN,SPART,ST5,SEPT8,TCF4,GPRIN3,AP4E1,CSMD1,RASD2,USP1,ZNF709,ZNF142,SLC30A4,PLSCR4,RGS7BP,TRAM2-AS1,TIGD6,NHSL1,SENP7" MicroRNA hsa-miR-30b*:mirSVR_highEffct hsa-miR-30b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-39 1.12E-35 6.84E-39 6.30E-38 132 959 "EMILIN3,OSBPL1A,APOC2,ARNTL,ARRB2,MARK4,NCOA1,NUMB,CHID1,SLC2A11,ATP6V1G2,TTLL9,CFLAR,ARHGEF7,GYG2,CLDN10,CCK,LDB2,CACNA2D2,CHN2,PPT2,ARMC8,LETMD1,COL11A2,CNRIP1,SEC31B,HAPLN1,NCOR1,CS,MROH8,SNCAIP,CSNK1G3,SOCS5,CST3,RIMS2,KATNAL2,ELMO1,FBXL5,SACS,ACOT8,DTNA,E2F5,AASDH,EBF1,PHC2,GOLGA7,PLEKHA1,SRRM1,GMPR2,CORO2B,FCGRT,CGREF1,ZNF44,C15orf41,GFRA2,TNRC6A,STARD3,GPD1,TDRKH,RNF165,AP4S1,RNFT2,NXPH3,FRMD5,NCKAP1L,ATXN2L,ZDHHC15,SHISA6,LRRC25,ZNF678,STXBP5,MAT2A,MBD1,MEST,AFDN,IDNK,NNAT,NOVA2,OGG1,GPR173,NALCN,XRN1,PLEC,NECAB2,DCHS2,VPS13C,PPP2R3C,TMEM255A,ACSS3,GTDC1,RGS4,CARF,ATAT1,KCNIP1,SEMA6D,FNIP1,SYBU,WDR47,FAM214B,ATF7IP,ZNF667,MYO16,DBNDD2,SPTAN1,LHPP,ZC4H2,ST5,SYN2,SYP,TACC1,TBCEL,FBXW11,DMXL2,ZFP90,SYNE1,USP32P1,TIAM1,TIMP4,ZNF346,SYNPO2,TRIO,STXBP4,RUSC1,ZNF189,ANKS1B,FTSJ1,TMEM178A,HPS4,TMEM63C,ACTR3B,KLHDC1,AP3B2" MicroRNA hsa-miR-188-5p:mirSVR_highEffct hsa-miR-188-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-39 1.13E-35 6.89E-39 6.34E-38 119 792 "SPOP,DPP10,PPFIA3,RGS20,TTLL9,RGS9,BCL7A,NRP2,DST,ARHGEF7,IL33,KALRN,PTBP2,VXN,CCNH,LRRFIP1,MAGI1,SEC31B,RNF14,VAC14-AS1,BOC,HDAC9,MATR3,DAPK1,ARMCX2,SPATA2,FBXL5,DDX46,GRIN3A,SLC12A6,RCAN1,WDPCP,PHF20L1,RABEPK,STX2,ST3GAL6,FDFT1,GORAB,FGF14,SUCO,PCYOX1,NBEA,FAM49B,ATP6V1H,STAU2,ALDH1L1,GDF9,ZNF638,FUT10,GRIA2,PLCD4,KAT7,ADAMTS6,MAP4K5,FRMD5,HNMT,NKD1,INSM1,KCND2,LMO2,MBD1,MBNL1,MGAT3,PCDH9,PDE4D,CYTL1,FAM216A,MTRF1L,PRKAB2,VPS13C,CNTLN,PTPRD,PTX3,STRC,CEP97,USP47,GTDC1,ZFHX4,DCUN1D2,SNX22,RPL15,FBXW7,ATAT1,ATXN2,ATXN7,FNIP1,KIF16B,CNKSR2,CCDC88A,EPC1,MYCBP2,KDM4C,ATP10B,LARP4,ELOVL4,ANKRD12,CAMTA1,AGTPBP1,SZT2,ITGB3BP,AP4E1,SLC44A1,TIAM1,TMPO,TSN,RPL7L1,FLRT2,RICTOR,AGMO,REEP1,UPF3A,STOX2,PRDM8,SLC17A7,PARP11,EPM2A,FAM13C,FZD3,RNF170" MicroRNA hsa-miR-215-5p:Functional MTI Functional MTI miRTarbase 2.06E-39 1.15E-35 7.03E-39 6.47E-38 116 755 "CLK4,AS3MT,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PHF12,PKP4,APC,IGDCC4,TMEFF1,ZBTB10,BARD1,BLM,DST,FUBP1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,B4GALT6,FAM189A2,AKAP7,FAM171B,LRIG1,APPL1,CTH,DBT,IRAK4,PCOLCE2,CEP85L,EXTL2,CLVS1,CORO2B,ST3GAL6,TMEM164,MEX3B,SEC23B,SEMA4D,SMC2,KHDRBS3,SARAF,SIGLEC8,GATM,KCNMB4,RAB40B,GPR37,CIT,PTPRT,FAM222A,ELOVL5,ZIC5,LRRCC1,IL6R,IL6ST,SLC35G1,KLHL23,TTYH2,LIMS1,MAN2A2,MEIS2,MXI1,SFR1,NUCB2,OPA1,SNX10,KCTD15,GPSM2,PRIMPOL,EPDR1,MAPK9,VPS13C,PTPRE,RADX,TRIM68,RET,RIC8B,RNASEL,MAP6D1,RMI1,HES6,ZFP30,FERMT1,ANKRD6,WDR47,KDM4D,RADIL,ARHGEF40,ZFP1,FAM126B,SSTR2,SS18,TBL1X,DICER1,SIRT1,C18orf54,ZMAT3,TMPO,ZNF346,UGT8,USP1,BCL2L13,CCDC14,ZBTB14,ZNF45,REEP1,ZNF184,EML6,NT5M,EPM2A,FAM182B,PHTF2,FBXO36" MicroRNA hsa-miR-519e:mirSVR_highEffct hsa-miR-519e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-39 1.16E-35 7.08E-39 6.52E-38 107 647 "CLK4,NCKAP5,KLHL32,ADCY6,KIAA1324,SMIM17,ARHGAP20,OGT,LGR5,ADAM23,ST3GAL5,SGCE,CA4,LRRFIP1,RCBTB2,SRSF11,C4orf33,ARMC8,AKAP6,CLOCK,CS,PDE4DIP,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,SNAP91,NR1D2,PDCD6IP,DNM1L,GOLT1B,PHF20L1,MRNIP,DCTN4,VPS13B,EPB41,EPB41L2,ENPP6,EXTL2,FGFR1,SUCO,HPCAL4,JKAMP,TMEM107,UFM1,GABRA3,IQGAP2,KIAA1841,USP19,RAB30,SOX21,PSIP1,HSPA1L,ZNF678,LMO2,MAT2A,MBD1,ZNF680,ZNF92,MYO6,SFR1,NF1,NOVA1,CDK18,PRTG,MTRF1L,RETREG2,BDNF-AS,PTPRB,PTPRG,FAT4,RASGRF2,CYB561D1,CSRNP3,HSPA4L,CNKSR2,DZIP1,ANKRD6,NUBPL,BTBD3,DHX30,CMTR2,ITPRID2,SSTR1,NECAB1,SYT1,ANKRD28,CAMTA1,MCF2L,SATB2,TCF12,SYNE1,DOCK9,PUM2,SIK3,NPL,ANKRD20A2,WIPF1,P2RY12,SMARCAD1,DHX33,EMSY,DNALI1,LINC02210,UBE3B" MicroRNA hsa-miR-660:mirSVR_highEffct hsa-miR-660:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-39 1.26E-35 7.66E-39 7.05E-38 117 768 "RNF150,ZNF608,RTL9,OSBPL8,TAOK1,UNC79,DPP10,PKP4,CCAR2,SLC2A11,DST,IL33,CALB2,CAPN3,SPAG9,CLDN10,CCNH,MAGI1,DLGAP1,CLGN,SRSF11,MS4A7,NDST3,CNGA3,GDA,SUSD5,PDE4DIP,CCDC144A,DGKB,GIT2,ZNF804A,DDX46,ALKBH8,DPP6,DTNA,MAMLD1,PHF20L1,AASS,IRAK4,VPS13B,SPEG,ETV1,GORAB,FOLH1,NBEA,MSANTD4,MPP6,MEGF10,ERAP1,MTHFD2,DISC1,ALDH1L1,GGT7,PPARGC1A,FUT10,ATP2B1-AS1,CIT,FAM19A2,ZHX1,ARHGAP36,MIER3,EID2B,LIMS1,NEK1,NF1,NRCAM,OPA1,PCDH9,PFKFB2,DUSP26,PLCL1,MAPKAP1,PPP2R2B,HYDIN,CNTLN,PTPRG,RAP1GDS1,RBBP6,ZMAT4,RFX3,ZNF532,YY1AP1,STK32B,MEG3,SEMA6D,SCP2,FERMT1,CHD9,FBXO11,CNKSR2,ABLIM3,SLC8A1,MYH15,LIMCH1,SPART,PBLD,NKAIN2,KLHL7,VPS13A,PLCB1,TAF9,TCF4,SATB2,ZFP90,HIF3A,ZFPM2,C18orf54,AMACR,TSC1,GORASP1,ZBTB14,ZNF184,LINC02210,WNK3,RGS7BP,AMN1,SENP7" MicroRNA hsa-miR-493:mirSVR_highEffct hsa-miR-493:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-39 1.39E-35 8.47E-39 7.79E-38 108 660 "RALGAPA1,NCKAP5,ADD1,KIAA1211,AP2A2,RTL9,PKP4,ARRB1,CADPS,PCDHGB4,TMEM108,ATP1B3,ATP6V1G2,ADGRB3,DST,CAMK2G,LRBA,ZMYM4,SRSF11,QKI,SLC4A8,SMARCAL1,ZFP28,GREB1,RUBCN,HEPH,DMD,DTNB,FAM78B,DNM1L,EIF4G2,PCOLCE2,CALCRL,EPHB1,RABEPK,SPEG,MRPL37,ANKMY1,TLR7,GMPR2,MRVI1,ZNF589,FGF13,GAD1,CPLX1,RAB30,TNRC6A,ZNF638,KDM2B,LILRB4,PCLO,GRM2,SOX21,NCKAP1L,HNMT,CELF5,GAREM2,JAK2,KCND1,KIF5A,KIT,KTN1,AFF1,TAGLN3,DNHD1,ZNF827,PCDHGC3,GNG2,PDZRN4,LRP12,SUSD4,SETD5,KLHDC8A,PCMTD2,MCMBP,TCP11L1,ABCA11P,NUBPL,PKNOX2,SLC12A4,RCOR3,SNRPN,HECW1,KDM4C,PEG10,ZNF302,ZSCAN29,SYN1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,USP32P1,C9orf85,CLHC1,WIPF1,KCNT2,TRIM9,EML6,ADAMTS9,ZNF30" MicroRNA hsa-miR-1269:mirSVR_highEffct hsa-miR-1269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.66E-39 1.49E-35 9.05E-39 8.33E-38 98 546 "PTCHD1,PCDH10,AMT,IGDCC4,PCDHGB4,BACH1,RGS9,SYNJ2,C5,IL33,NFS1,P2RX6,ZMYM4,CFL2,TPP1,QKI,ARHGEF6,COL4A5,AHCTF1,VCAN,SLITRK5,DAPK1,YTHDC1,ELMO1,ALKBH8,SV2B,WDR20,RAB39B,E2F6,FSD1L,EMX2,VPS13B,EXTL2,CEP78,OLFM1,SYNCRIP,NOP56,TVP23A,PCDH17,GGT5,LOXL3,ZHX1,IL6ST,STXBP5,CLEC18A,MAP2,AQP11,MEIS1,AFDN,MSR1,NEK1,PCDHGC3,ZNF655,PPP3CA,RGS4,ATP8B4,ADAL,SEMA6D,SH3GL3,FBXO11,SLC9A5,ELMO2,IFT122,LIMCH1,SNAP25,MBD5,ZNF415,SNRPN,NEK4,NECAB1,TMEM150C,ALG1,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,ZFPM2,GPR161,TIAM1,TK2,ACTR6,TRO,UGT8,ZNF70,SLC30A3,MFF,ADAMTS9,NAV3,FZD3,JPH3" MicroRNA hsa-miR-550*:mirSVR_highEffct hsa-miR-550*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-39 1.68E-35 1.02E-38 9.41E-38 94 503 "GALNT13,BEND6,NME5,SPOP,USP35,SRPX,PCDH10,CDC42BPA,PPP4R4,ZSCAN18,NUMB,CA8,RUNX1T1,ZNF501,SLC16A4,C2CD2,CRHBP,VCAN,SOCS5,APPL1,IST1,PITPNC1,RHOBTB1,DTNA,EDN1,FRY,FAM13A,PHF20L1,EPB41,RASGRP2,NCALD,ZNF585B,DLC1,SYNCRIP,OGA,DISC1,PCDH17,KDM2B,GNAO1,TOX2,ZDHHC15,INSM1,ITPKB,KCNJ16,KCNN2,KIF2A,HECTD2,MAP6,MBNL1,EFHB,SHC3,MEF2C,MEIS1,SRSF12,KITLG,MID1,AFDN,NCF2,GPR137C,CNTN3,PCDH8,PDE4D,ZNF655,FAM218A,PRPSAP2,VPS13C,PTPRE,HKR1,CRTAC1,PCMTD2,RPE,ZNF568,CSRNP3,NUBPL,SNRPN,SAMSN1,TTBK2,DIP2A,PLCB1,C12orf76,ALG1,TCEA1,SATB2,DOCK9,USP32P1,TMPO,RUNDC3B,SGK3,GUSBP1,TRIM9,ZFAND5,EMSY,PHTF2,MSRB3" MicroRNA hsa-miR-505*:mirSVR_highEffct hsa-miR-505*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.12E-39 2.30E-35 1.40E-38 1.29E-37 106 640 "RALGAPA1,KCNH8,ADD2,KIAA1211,ZNF608,CC2D2A,ADGRF5,MAP4K3,PKP4,APC,SLC2A11,TTLL9,BACH1,CACNA1B,PRC1,LDB2,TIGD7,EPS15L1,PPT2,LY86,CRMP1,TRIM69,SEC24C,PDE4DIP,DCAF8,TMEM170A,DAPK1,ZC3H11A,FAM107B,SEC16A,EXOG,DNAH9,SLC25A18,PHC2,VPS13B,FAM198B,CEP78,FER,AGAP3,NOP56,AKAP3,CINP,PDLIM5,FYB1,HRASLS5,ERAP1,ZNF559,DISC1,TUBA8,TNRC6A,ZNF638,GPR12,GRIA2,FAM19A2,COQ10A,AQP11,XRRA1,MSR1,MT1M,NRCAM,NTRK3,OCRL,PDE3A,SEMA5B,KCTD15,STRN3,HYDIN,PIGG,CNTLN,BDNF-AS,TMEM260,PTPRG,RAD51D,SUSD4,GTDC1,NUDT11,CARF,GSTCD,ELP2,SNX22,NEK11,NCBP3,LRFN5,SCP2,CASC3,SLA,SIRT2,RCOR3,IFT122,SNCA,SNRPN,KDM4C,PBLD,TRIM2,FRYL,ENHO,TIAM1,PIK3R5,TPM2,SYNPO2,ZNF709,PLPPR2,XRCC4,LYPD6,SLC30A4,AP3B2" MicroRNA hsa-miR-106b*:mirSVR_lowEffct hsa-miR-106b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.32E-39 2.42E-35 1.47E-38 1.35E-37 98 549 "ACADM,AP2A2,AMPH,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,VAT1L,LINC00173,NCOA1,RNF182,DST,SCAPER,C5,CAMK2A,RHBDL1,CBLN1,MTMR7,SEPT7,LRRFIP1,TIGD7,B4GALT6,CNN3,ARHGEF6,C1QL2,CNTNAP2,DZIP3,ERC2,RIMS2,CCDC144A,CYBB,ARHGAP24,KIAA0586,PITPNC1,KIAA0753,DOCK2,DPP6,ABCC5,E2F6,EIF4G2,CALCRL,GPHN,ACSL4,SLC9B2,OLFM1,AMOTL2,MEX3B,WDR83,FYN,CACFD1,SLC2A6,ATOH8,ELOVL5,ZNF678,MATN2,LRP1B,KCTD6,GIT1,NEK1,NFE2L2,NUCB2,PCSK5,PIK3R1,ING3,GRAMD1C,BCAS3,CNTLN,TMEM260,PTPRB,PTPRO,REV3L,RGS12,ROBO2,RPE,NEK11,SGSM1,SATB1,ATXN7,PUF60,BTBD3,ARHGEF40,MTERF2,RCOR3,SP4,MYCBP2,ZNF423,CLSTN2,PJA1,EXOC7,PCDHA2,CYB561A3,ITGB3BP,NUTM2A,LAT2,POLR3H,HRASLS,JMJD1C" MicroRNA hsa-miR-153:PITA hsa-miR-153:PITA_TOP PITA 4.37E-39 2.45E-35 1.48E-38 1.37E-37 78 343 "XKR4,USP31,OSBPL6,APC,SEMA4G,CDK13,SLC4A4,LDLRAD4,CAMK2G,DLGAP2,CFL2,CLTC,CNN3,AKAP6,MFAP3L,KLHL3,DMD,MAMLD1,SCML2,CAMKK2,DOT1L,GATM,PPARGC1A,TNRC6A,PCLO,RNF165,MAP4K5,MIER3,KCND1,KCND2,IPO5,STXBP5,MAT2A,MATN2,SCAMP5,MITF,TAGLN3,ZC3H12B,NFE2L2,GPR85,PIK3R1,CCSER2,LRP12,PPP3CA,KANSL1,PTCH1,PTPRD,RIC8B,ROBO2,RYR3,FAM81A,WDR47,EPC1,GKAP1,SNAP25,SNCA,SOX11,PLCB1,SYN2,SYT1,TCF4,DMXL2,CUX2,ZFPM2,SGK3,FLRT2,WIPF1,SPHK2,DPYSL5,LAMP5,SLC30A3,CADM2,SLC38A1,PRDM10,NAV3,RGS7BP,FZD3,UBE3B" MicroRNA hsa-miR-1910:mirSVR_highEffct hsa-miR-1910:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.47E-39 2.50E-35 1.52E-38 1.40E-37 112 712 "PWWP2A,ARHGAP20,AMPD3,DDO,CDK13,DYNLL1,EIF4G3,DPY19L3,KALRN,PTBP2,CARS,CDC25B,RAB28,C4orf33,ARMC8,LETMD1,SNCAIP,PDE4DIP,PUM1,DCAF4,KATNAL2,DCAF8,DAPK1,BRINP1,RHOBTB1,DYNC1I1,DPH1,HIPK3,FCF1,YAF2,CELSR3,EGFR,KMT5B,ING4,EMX2,ZNF549,DLC1,GORAB,FGF13,RAPGEF6,MTHFD2,RUNDC3A,CBX1,ZBTB45,VSIG4,RBPJ,SCIN,KIF5A,STMN1,MAT2A,AQP11,MEIS1,MEIS2,ZNF92,NF1,GNG2,PIK3C2A,NLE1,PCDH18,SMIM7,PKIA,HYDIN,WDR25,PTN,PTX3,USP47,ZFHX4,GSTCD,YY1AP1,SNX22,ATP8B4,TCP11L1,MEG3,ABCA11P,KCNIP1,SALL1,SCN2B,FOXRED1,ZFP30,ASAP3,FNDC3A,CNKSR2,BTBD7,SLC22A4,SMARCA4,ANKRD36,SNRPN,KDM3A,GLT8D1,ZC4H2,ZSCAN29,SYNE2,SYP,SYT1,SYNE1,PCDHB6,TEK,KHDC1,AP4E1,GPR161,CSMD1,NPL,METTL3,TRPS1,MTCH1,PLPPR2,CELF4,SPIRE1,SMARCAD1,TMEM63C,FBXO36,CPNE4" MicroRNA hsa-miR-574-5p:mirSVR_highEffct hsa-miR-574-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.52E-39 2.53E-35 1.53E-38 1.41E-37 116 761 "ACTN1,INTS2,ALK,AMPD3,ARRB2,INSYN2B,STX16,TTLL9,ADAM15,ADGRB2,CA4,CACNA1A,KALRN,PTBP2,CCK,LRBA,CCPG1,NUMBL,RCBTB2,CHN2,MS4A7,TAOK2,EPS15L1,FAM189A2,CNR1,CPS1,SEC31B,NCOR2,CS,AATK,CSF1,CYBB,DCAF8,ZNF337,DGKG,ZC3H11A,SPOCK3,AASDH,EDN1,ANKRD46,PHF20L1,TMEM35A,CLVS1,ZNF589,FGF11,SYT3,AKAP3,STAU2,GABBR1,FAM120B,ZNF559,SYT17,IGSF5,SESN1,TTBK1,PLCD4,ZHX1,HSF2,ZIC5,LRRCC1,IL6ST,SLC35G1,KCND1,LAMP2,MOV10,MPP2,MSR1,NTRK3,PFKFB4,SEMA5B,PPP2R5E,CEP41,MASP1,CNNM2,CYBC1,PIGG,BDNF-AS,PID1,ZDHHC14,MSANTD2,TRIM68,FIGN,RNASEL,TMLHE,CARF,ATP8B4,ATAT1,SCN8A,FNIP1,SUPT20H,SLC4A3,SLC6A8,SLC14A1,ATF7IP,LGI3,SNAP25,KIF13A,CMTR2,SP4,RGL1,STXBP1,NUDT10,TMEM150C,ZFP90,RPGRIP1L,ARHGAP9,PRRT1,STXBP4,HSPBP1,UGT8,ZNF28,CELF4,SH3GLB2,PRTFDC1,KAT6A,ZDHHC20" MicroRNA hsa-miR-766:mirSVR_highEffct hsa-miR-766:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.13E-39 3.43E-35 2.07E-38 1.91E-37 115 751 "ACADM,ASIC1,METAP1D,AP2A2,TAOK1,AMPD2,SUGT1P4-STRA6LP-CCDC180,NT5C3B,PPFIA3,RGS20,DNAH17,RIPK1,MTMR2,RAB29,CALB2,CDH2,RAB33A,AKAP6,VAC14-AS1,PLXNA4,FAM169A,GREB1,DCAF4,CYBB,GPRASP1,DNM1,HS3ST2,DTNA,TOM1,FARSB,PHC2,PHF20L1,PAN3,TLR7,F8,ATP13A4,NOP56,DCTN2,RAPGEF6,ZNF274,ZNF559,DISC1,TUBA8,SESN1,TNRC6A,GPD2,GRIA2,PLCD4,BTN2A1,RNFT2,MAP4K5,ATXN2L,HNF4G,IGF1,ZNF678,INSM1,CDH20,STMN1,ZFYVE27,MBD1,TM6SF1,LAYN,RTL5,PCBP3,NUCB2,DUSP26,NLGN3,MINDY2,PPP1R1A,WBP1L,TMEM104,QDPR,SLC25A48,ZNF493,RET,ZDHHC4,RGS4,EXD2,NEK11,EPHA10,GLDN,TCP11L1,SALL1,LRFN5,SEC14L1,SH3GL3,SLC9A5,MYH15,KIF13A,FAM219A,PDZD2,KDM4C,SPTB,LARP4,NKAIN2,APOM,CEP68,SEPT3,SYNE2,ARHGEF9,FBXW11,GPRIN3,MTMR14,TPM1,HSPBP1,SLC35A4,BCL2L13,SLC47A2,ZNF28,MKRN3,CADM2,GDPD5,HPS4,PPP1R3F,CASC15" MicroRNA hsa-miR-4303:mirSVR_highEffct hsa-miR-4303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.36E-39 3.56E-35 2.15E-38 1.98E-37 114 739 "ACADM,KDM5D,PWWP2A,INTS2,ZFAT,ANK2,SUGT1P4-STRA6LP-CCDC180,APC,TNRC6C,LGR5,ATP2A2,BACH1,DST,SGCE,KALRN,PTBP2,CDC25B,TIGD7,CNTN1,TOGARAM2,ZFP28,RNF14,TRIM69,CSF2RA,ARHGEF10,PLXNA4,UBXN2A,MAML1,DDX46,EXOG,RCAN1,EBF1,FCF1,ASB3,LRRC17,CDKL3,EYA1,F5,ST3GAL6,FCGR3A,FDFT1,SUCO,UBE2E3,FLT1,PSD2,STAMBP,ATP2C1,STAU2,GABBR1,GAD1,ALDH1L1,LUZP2,PRUNE2,DIDO1,FAM19A2,PSIP1,HMGCL,C9orf129,TJAP1,C2CD4C,CNOT4,NUCB2,CLDN11,GPR85,OLA1,NLE1,PURG,DRAM2,PPM1B,NKAIN4,PIGG,STK32A,ACSM5,SLC25A48,FAT4,RFX3,EXD2,RPE,ZNF568,ATXN7,SCP2,FNIP1,KIF21A,FERMT1,SEC31A,SIRT2,SLC12A2,BTBD7,SNRPN,ZSWIM8,ZNF423,LHPP,ITPRID2,ZSCAN29,ADHFE1,KLHL7,NECAB1,SYNE2,RHBDL3,SLC37A2,MTCL1,SYNE1,RELL2,TK2,RIMBP2,TPM1,SYNPO2,TRO,TRIM9,CELF4,LINC02210,RNF103,RGS7BP,CASC15" MicroRNA hsa-miR-509-3p:mirSVR_highEffct hsa-miR-509-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.73E-39 3.77E-35 2.28E-38 2.10E-37 102 597 "BEND6,TXNDC16,ARRB2,MARK4,ADAM23,DST,SYNJ1,CALB1,PTBP2,CAMK2A,LOC730101,RCHY1,CSNK1G3,SLITRK5,APPL1,KATNAL2,ZFYVE16,ZC3H11A,RHOBTB1,PDCD6IP,EDNRB,FCF1,PHF20L1,STARD3NL,CALCRL,ENPP6,NCALD,ANKMY1,NRN1,FAM198B,TAOK3,ATP13A4,CHL1,GAD1,TCERG1,GNAO1,RNF165,FRMD5,VSIG4,LRRC75A,LRRCC1,LRRTM1,HECTD2,MAT2A,MEIS1,KCTD6,N6AMT1,ZNF92,NNAT,NME4,NTRK3,PCDH9,ENPP2,SEMA5B,PIK3C2A,FAM218A,DRAM2,PRKACB,PKIA,MASP1,GDPD2,PTPN13,PTX3,SH3TC2,FAT4,ZNF493,RASGRF2,SETD5,KLHDC8A,PNMA8A,RORB,ELP2,ABCA11P,CLIP1,FAM192A,SEMA6D,SH3GL3,ABLIM3,SLC2A5,SEPHS1,PBLD,CLASP2,ANKRD28,PJA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RIMBP2,LGI4,TRIM9,ZNF138,SPIRE1,STOX2,MDH1B,RGS7BP,TRAM2-AS1,NETO2" MicroRNA hsa-miR-639:mirSVR_lowEffct hsa-miR-639:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.04E-39 3.94E-35 2.38E-38 2.19E-37 94 508 "DGCR6,CCDC85A,CC2D2A,SEMA6A,LTBP4,OGT,PARG,SFMBT2,MARCH3,CCAR2,SYNJ2,CALB2,CBR1,MAGI1,ASIC3,NDST3,NRXN3,HECTD1,GDA,SNCAIP,CTH,RIMS2,DCAF4,MYADM,SNPH,SPOCK2,SPOCK3,HS3ST2,EMX2,EPB41L2,RCAN2,NCALD,SPEG,MRPL10,EZH1,CLVS1,FGF14,AGAP3,PCDH17,STARD3,FUT10,CLASRP,KCND1,KCNJ16,KHK,CREG2,LSS,ZFYVE27,MBNL1,PPM1L,AFDN,NFE2L2,NFYA,NLGN3,IRX1,KLK6,GDPD2,PTK2,PTPRE,RNASE1,NEK11,RPS6KA2,KCNIP3,ZNF331,SBF1,SMPD3,GALNT10,COPZ1,LGI3,ARFGAP1,INAVA,SNRPN,ZSWIM8,TSPYL2,LMO3,SS18,DIP2A,CYB561A3,PMS2CL,TIAM1,MTMR14,R3HDM1,CSMD1,SMUG1,RUSC1,VLDLR,XRCC4,LGI4,EML6,DNALI1,SEMA3B,HNRNPA3,PRRT4,JPH3" MicroRNA hsa-miR-185*:mirSVR_highEffct hsa-miR-185*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.27E-39 4.07E-35 2.46E-38 2.26E-37 103 609 "ASPHD1,ASIC1,SYS1,ADRA1D,ZFAT,PI16,TNRC6C,MADD,CDK13,GPC2,KALRN,RUNX1T1,P2RX6,TIGD7,C7orf61,CNGA3,CPS1,SH2B1,CLIP3,SEC24C,PDE4DIP,USP6NL,GAPVD1,ARHGAP24,AIF1L,MYEF2,POM121,EXOG,FIS1,EDN3,YAF2,PAN3,ERBB2,AMOTL2,IP6K2,IQCG,FLNC,FOLR2,USP21,MEGF11,MEGF10,ZNF234,DISC1,TTBK1,POLL,GNAO1,GPT2,STON1,BTN2A1,CLASRP,FAM107A,ARHGAP36,INPP5B,KCNK3,MYO7A,SETD4,PALM,PDE1B,GPR173,CCSER2,PLTP,EPB41L4B,POLR2F,FSD1,PTPRO,NKAIN1,CCDC40,SUSD4,KIAA0895L,ATAT1,SATB1,CASC3,ASAP3,FUZ,FHOD3,EPN2,SIRT2,SLC14A1,RCOR3,TTC17,CABCOCO1,SOX3,ERC1,NFASC,NKAIN2,DIP2A,CAMTA1,DNMBP,MGRN1,USP32P1,MTMR14,HEY1,CABIN1,TPM2,KCNE5,GORASP1,KLC2,ATP6V0E2,TMEM198,PCBP1-AS1,SLC30A3,DNALI1,JPH3" MicroRNA hsa-miR-1268:mirSVR_lowEffct hsa-miR-1268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.68E-39 4.30E-35 2.59E-38 2.39E-37 112 716 "ADCY6,KIAA1211,SORCS2,PHYHD1,AQP6,CHID1,ATP1A3,JAZF1,CAMK2G,P2RX6,ARHGEF1,SCARB1,KCNAB3,EVI5L,NOG,FBXO7,WHRN,ABI3BP,AHCTF1,ZNF385A,ANKRD44,FAM131B,IP6K1,DGCR5,B3GAT3,POM121,DNM1,DPH1,ACOT8,RCAN1,TOM1,SNX29,EIF4G2,EPHB1,MRPL37,TMEM132C,SCML2,SPSB4,AGAP2,EFCAB2,POMT1,UFM1,SIGLEC8,ZNF276,POLL,GPT2,BTN2A1,RABL2A,PADI2,MAN1B1,ATXN2L,VSIG4,SYNPO,CELF5,KNDC1,INPP5B,ITGAM,KCNN2,MAT2A,MEIS2,KITLG,MITF,MYO7A,ZNF713,ZNF827,CDK18,FA2H,PPP2R5E,PTPRN,ZNF493,ZDHHC14,FIGN,BAALC,STK32B,MEG3,STX1B,ATXN2,ST6GAL1,NUBPL,PKNOX2,SLC6A8,SLC11A1,SLC12A4,LGI3,CMTR2,ZHX3,ZSWIM8,UNC5B,MCF2L2,CAMTA2,SSTR2,STXBP1,ADAMTS17,ARC,SYT5,ALG1,MGRN1,TNS2,HIF3A,AP4E1,GALNT17,PIK3R5,RASD2,TRIO,TSN,LAT2,ZNF19,TRIM9,LINC02210,DOCK8,RTN4,TTC7A" MicroRNA hsa-miR-1178:mirSVR_highEffct hsa-miR-1178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.80E-39 4.36E-35 2.63E-38 2.42E-37 111 704 "ASPHD1,KDM5D,PTCHD1,RTL9,TXNDC16,ABCD2,CCDC146,PKP4,PARG,UPRT,ZSCAN18,EIF4G3,ADAM23,RGS9,NRP2,SYNJ1,SGCE,SPAG9,DGKI,LRBA,CACNA2D2,SRSF11,RAB33A,TMEM184B,ARMC8,SLC4A8,ZNF385A,RNF14,SOCS5,PHF14,DOCK4,ZFYVE16,PABPC5,ZBTB24,EXOG,CPEB2,EDNRA,EGR3,COQ7,NCALD,NRN1,MEX3B,NELFCD,PDLIM5,AP4B1,CHL1,IQGAP2,DISC1,MSTN,HPGDS,MSL3,CBX1,KDM2B,STON1,MCHR1,GRIA2,PSIP1,GABARAPL2,LRRCC1,LAMP2,MARK1,MAT2A,TM6SF1,MEIS1,MIA2,POC1B,MITF,MYO9A,NEK1,NF1,GPR85,NALCN,SH3KBP1,CNTLN,ENOX1,ZMAT4,RGS12,RIC8B,CARF,PCMTD2,CCDC102B,MRAP2,MEG3,ATAT1,DGLUCY,FERMT1,SEPHS1,BTBD7,SNCA,HECW1,KDM4C,ZC3H13,SSTR2,PRRC2C,PCDHB10,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TMPO,RIMBP2,SYNPO2,STXBP4,ST7,HNRNPA3,MSRB3,SENP7" MicroRNA hsa-miR-1255a:mirSVR_highEffct hsa-miR-1255a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.86E-39 4.40E-35 2.65E-38 2.44E-37 110 692 "CLK4,KLHL32,PLEKHH1,KCTD16,TAOK1,ADGRF5,SPOP,ALCAM,SUGT1P4-STRA6LP-CCDC180,PDE8B,NUMB,ATP1B3,ATP2A2,ADAM15,RGS9,ZNF599,CASTOR3,CAMK2G,VXN,RUNX1T1,ZNF501,CFL2,PLEKHB1,CNTN1,COL9A3,CSF1R,ARHGEF10,OSBPL3,DZIP3,ARHGAP24,TBC1D5,DAPK1,SV2B,DPYSL2,SLC25A18,ANKRD46,SUGP2,TLR7,SIRPB1,FGFR1,OGA,HRASLS5,GABRG2,NEU3,TUBGCP4,CYP46A1,GNAL,WDFY3-AS2,PLCD4,GRIK4,AP4S1,ATXN2L,HNMT,SYTL4,MAP2,P2RY13,ALDH1L2,IGSF11,OPA1,GLIPR1L2,CDK18,ING3,SH3KBP1,PPP3CA,EPDR1,SAMD9,BDNF-AS,PTPRG,ZNF493,RGS4,RNASEL,C12orf49,PNMA8A,NEK11,ADAL,S100B,ATXN2,PRCD,SGK1,NLGN1,KANSL3,TTC17,NMNAT2,KDM4C,DDN,ATP10B,SSTR1,ZC4H2,STXBP1,NECAB1,NUDT10,CAMTA1,SATB2,ZFP90,RPGRIP1L,SZT2,ZNF346,RPL7L1,UBE2H,UBE3A,WIPF1,CLDND1,CELF4,SLC30A3,PRDM10,HPS4,ST7,PHTF2,RNF146,LAS1L" MicroRNA hsa-miR-4327:mirSVR_highEffct hsa-miR-4327:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-39 4.68E-35 2.82E-38 2.60E-37 101 587 "DPY19L2P4,AGT,APC,ARNTL,EIF4G3,DPY19L3,BACH1,KSR1,SYNJ1,CACNA1B,ABI3BP,CNRIP1,ABCG1,RGS6,ERC2,PUM1,GPSM1,EARS2,MYEF2,SV2B,CHRDL1,DTNA,EBF1,SNX29,YAF2,GOLGA7,RGS17,EMX2,ADGRV1,EZH1,RACK1,SEC24B,POLR1B,BAIAP2,IP6K2,SLC37A3,AKAP3,ADAM28,SPIN1,KDM2B,WDFY3-AS2,CNTRL,KCNN2,IPO5,AFDN,MXI1,MYO6,NF1,NTRK2,PCSK5,GNG2,SDK2,ING3,MAPK9,GRAMD1C,CNTLN,PTPRD,NKAIN1,PID1,GSTCD,ROBO2,ELP2,ABCA11P,TRAPPC13,SALL1,FNDC3A,CNKSR2,RCOR3,ZNF415,SNRPN,RBM26,PBLD,PRRC2C,PLCB1,SYN2,COBL,MTCL1,CUX2,SYNE1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,RIMBP2,R3HDM1,LAT2,ZBTB38,STOX2,MPPE1,WNK2,EPM2A,FAM13C,DOCK8,RTN4,CASC15,MSRB3" MicroRNA hsa-miR-22-3p:TargetScan hsa-miR-22-3p TargetScan 9.59E-39 5.36E-35 3.23E-38 2.97E-37 88 446 "EMILIN3,FMNL2,RNF150,AK2,PDZD4,BIN1,DPP10,PHF12,APBB2,ARRB1,CDK13,NCOA1,MTMR2,CABP7,CAMK2G,DGKI,DLGAP2,CSF1R,RIMS4,KIAA0040,PLCXD3,HDAC4,IP6K1,EDNRA,FEM1B,EMX2,EPB41L2,ERBB4,ETV1,DNAJC27,EZH1,SEC23B,FAM49B,CELF1,FUT9,MEGF11,MTHFD2,GATM,KCNMB4,KAT7,PADI2,NXPH3,IL6R,MAT2A,ADAM11,MEIS2,PPM1L,MYO9A,NFYA,NTRK2,PALM,PAX6,OLA1,MAPK10,KHDRBS2,DPF2,ERI2,GTDC1,RGS3,RIC8B,ALG9,ARMC5,FBXW7,GLDN,HUNK,CSRNP3,PRCD,CHD9,CNKSR2,EPC1,KDM3A,ARHGAP26,DBNDD2,CAMTA2,NXT2,MMS19,SATB2,ARHGAP9,ITGB3BP,GPR161,KAT6B,PDSS1,CLIP2,KCNK12,MAP3K12,KAT6A,HNRNPA3,LAS1L" MicroRNA hsa-miR-1284:PITA hsa-miR-1284:PITA_TOP PITA 1.30E-38 7.28E-35 4.38E-38 4.03E-37 86 427 "KCNH8,FMNL2,AXIN2,PTCHD1,ADRB2,HACE1,OSBPL8,ADGRF5,SEMA7A,ATP2B2,CARMIL3,JAZF1,LDLRAD4,KALRN,FOXN3,RAB33A,CLCN3,QKI,PLCXD3,PUM1,SPOCK3,CPEB2,PAN3,EPB41L2,RCAN2,GPHN,DENND4A,TAOK3,KAT8,FOXO3,ST6GALNAC3,PCDH17,GHR,SPIN1,FAM19A2,SOX21,MIER3,IGF1,JAK2,KCNQ3,STMN1,PACRG,MAP2,MARK1,MEF2C,MITF,AFF1,ZC3H12B,NRCAM,NTRK3,PDE4B,EPB41L4B,SNRK,PTCH1,TMEM260,FAM184A,ENOX1,OXR1,REV3L,ROBO2,FNIP1,TRA2B,SCAF8,KIF21A,FNDC3A,CXXC4,TMCC1,FAM126B,DOP1A,CDK19,NFASC,ERBIN,CAMTA1,TCF4,TRIM2,ZFPM2,AKTIP,EIF4ENIF1,PLEKHH2,VLDLR,ZIC2,SMARCAD1,RTN4,FRMD6,SOCS4,SENP7" MicroRNA hsa-miR-1255b:mirSVR_highEffct hsa-miR-1255b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-38 7.60E-35 4.57E-38 4.21E-37 108 672 "CLK4,KLHL32,PLEKHH1,KCTD16,TAOK1,ADGRF5,SPOP,ALCAM,SUGT1P4-STRA6LP-CCDC180,PDE8B,NUMB,ATP2A2,ADAM15,RGS9,ZNF599,CASTOR3,CAMK2G,VXN,RUNX1T1,CFL2,PLEKHB1,CNTN1,COL9A3,CSF1R,ARHGEF10,OSBPL3,DZIP3,ARHGAP24,TBC1D5,DAPK1,SV2B,DPYSL2,SLC25A18,ANKRD46,SUGP2,TLR7,SIRPB1,FGFR1,OGA,HRASLS5,GABRG2,NEU3,TUBGCP4,CYP46A1,GNAL,WDFY3-AS2,PLCD4,AP4S1,ATXN2L,HNMT,SYTL4,MAP2,P2RY13,ALDH1L2,IGSF11,OPA1,GLIPR1L2,CDK18,ING3,SH3KBP1,PPP3CA,EPDR1,SAMD9,BDNF-AS,ZNF493,ERI2,RGS4,RNASEL,C12orf49,PNMA8A,NEK11,ADAL,S100B,ATXN2,PRCD,SGK1,NLGN1,KANSL3,TTC17,NMNAT2,KDM4C,DDN,ATP10B,SSTR1,ZC4H2,STXBP1,NECAB1,NUDT10,CAMTA1,SATB2,ZFP90,RPGRIP1L,SZT2,MTMR14,ZNF346,RPL7L1,UBE2H,UBE3A,WIPF1,CLDND1,ZNF17,CELF4,PRDM10,HPS4,ST7,PHTF2,RNF146,LAS1L" MicroRNA hsa-miR-92a-1*:mirSVR_highEffct hsa-miR-92a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-38 8.66E-35 5.20E-38 4.79E-37 92 491 "SYN3,FAM135A,AMT,PPFIA4,PHF12,SEMA4G,RGS9,NRP2,CACNA1B,CBLN1,CBR1,MAGI1,UBE2L6,TPP1,IQCK,PCYT1B,AKAP6,GDA,CLIP3,RGS6,SEC24C,DDX46,ALKBH8,USP3,DTNA,ECM2,EDN1,EMX2,EPB41,EPHB1,SIRPB1,FCGR3A,IP6K2,RASL10A,B4GALNT1,KIAA1841,TCERG1,LUZP2,DCLK2,SOX21,SOWAHA,NKD1,HECTD2,MBNL1,LRP1B,MEIS1,MEIS2,KITLG,NFE2L2,NNAT,SMIM11A,PDPK1,ZDHHC8,PLIN1,ANKRD16,PILRA,DRAM2,PRKAB2,TMEM260,EML5,NWD1,HKR1,ZDHHC14,FBXW7,ATAT1,ZFP30,ARX,MYO18A,FAM81A,FAM214B,PKNOX2,HECW1,DDN,CLSTN2,SAMSN1,SEPT8,TACR1,ADGRL3,FBXW11,ZFP90,FRYL,ZNF346,TRPS1,SLC35A4,WIPF1,TMEM178A,CIAPIN1,RGS7BP,KAT6A,TMEM63C,FBXO36,NETO1" MicroRNA hsa-miR-1185:mirSVR_highEffct hsa-miR-1185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-38 9.99E-35 6.00E-38 5.53E-37 110 698 "KDM5D,NDRG3,SMIM17,ATP1B3,STX16,CFLAR,SYNJ1,CA8,RUNX1T1,KRIT1,L3MBTL4,CDO1,UBE2L6,ABCG2,HINFP,SNCAIP,PABPC5,HEPH,TMCC2,DPP6,DNM1L,GOLT1B,EDNRA,ANKRD46,SEMA3D,TMTC1,YAF2,PHF20L1,SUGP2,PPP1R1B,GORAB,FGF13,FGF14,AKAP3,ATP6V1H,ZNF605,CGREF1,CHL1,GABRB3,TRAF3IP2,DISC1,KIAA1841,GGT5,CRCP,RAB30,LUZP2,ADGRA3,LPAR4,ADAMTS6,MSL1,LRRCC1,IL6ST,SLC35G1,STXBP5,MAT2A,MATN2,SHC3,BLOC1S2,MYO7A,P2RY13,NCAM2,NF1,ETFRF1,PCDH18,STRN3,ING3,APTX,C1orf109,CEP97,OXR1,RGS4,LGI2,ZNF532,TMLHE,ZNF568,TRAPPC13,LRFN5,CASC3,MRAS,SYBU,NLGN1,SLA,SLC12A2,CPEB4,MBD5,MYO16,CLASP2,SS18,APOM,SEPT8,STXBP1,PRRC2C,SYT1,CAMTA1,TCF12,ARHGAP9,DICER1,TRPS1,TSN,CFAP298,UPF3A,LINC02210,RNF103,HPS4,WNK3,PARP11,AMN1,ST7,PHTF2,JPH3" MicroRNA hsa-miR-515-3p:mirSVR_highEffct hsa-miR-515-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-38 1.01E-34 6.03E-38 5.55E-37 108 674 "NCKAP5,ADCY6,ADD1,ZNF608,KIAA1324,SMIM17,ARHGAP20,OGT,ADAM23,SGCE,CA4,LRRFIP1,RCBTB2,SRSF11,IQCK,ARMC8,AKAP6,CPS1,CLOCK,CS,PDE4DIP,CST3,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,SNAP91,NR1D2,PDCD6IP,DNM1L,PHF20L1,MRNIP,DCTN4,EPB41,EPB41L2,ENPP6,DNAJC27,FGFR1,SUCO,HPCAL4,JKAMP,TMEM107,UFM1,GABRA3,IQGAP2,SYT17,KIAA1841,GATM,GGT7,RAB30,SOX21,PSIP1,ZNF678,LMO2,MAT2A,MBD1,ZNF680,ZNF92,MYO6,SFR1,NF1,NOVA1,TBC1D25,CDK18,PRTG,MTRF1L,RETREG2,BDNF-AS,PTPRB,PTPRG,FAT4,RASGRF2,PNMA8A,CYB561D1,CCDC102B,CSRNP3,HSPA4L,CPEB3,DZIP1,ANKRD6,NUBPL,BTBD3,DHX30,RCOR3,CMTR2,ITPRID2,SSTR1,SYT1,ANKRD28,CAMTA1,MCF2L,TCF12,SYNE1,DOCK9,PUM2,SIK3,KAT6B,NPL,ANKRD20A2,WIPF1,SMARCAD1,DHX33,DNALI1,LINC02210,UBE3B,DPF3" MicroRNA hsa-miR-409-5p:mirSVR_lowEffct hsa-miR-409-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-38 1.21E-34 7.25E-38 6.67E-37 113 736 "KLHL32,BEND6,OSBPL8,ABCD2,FGD2,CADPS,ZBTB10,ADAM23,ADGRB3,SYNJ1,CALB1,PTBP2,CAST,RGN,CD38,C1orf52,DGKI,CDC25B,LOC730101,NRXN3,PLAA,OSBPL3,CCDC144A,DOCK4,HDAC9,YTHDC1,MYEF2,KIF19,FCF1,TMTC1,SUGP2,TENM1,C8orf37,USPL1,EIF1,LRRC17,RASL12,ZSCAN30,SEC24B,FER,OLFM1,FGF12,POLK,SEMA4D,NBEA,CSPG5,SDCBP2,CHL1,IP6K3,DISC1,DCLK2,GPD1,TMEM121B,PCLO,FAM19A2,PSIP1,ADAMTS6,IL12A,INSM1,LAMA2,AFF1,NFE2L2,OPA1,OPRL1,GPR137C,CNTN3,PFKFB2,SNX10,EPB41L4B,DRAM2,VPS13C,TMEM260,REV3L,MORC4,RGS4,RGS12,KIF7,RPL15,KCNIP3,RTN1,AP1AR,SEMA6D,HES6,SH3GL3,SYBU,WDR37,DHX30,MYH15,MBD5,PEG10,NFASC,ITPRID2,SAMSN1,NXT2,ARHGEF9,VPS13A,KIAA1107,RPGRIP1L,SIK3,AP4E1,TMPO,TRPS1,RPL7L1,OSBP2,VLDLR,PCDH20,WNK2,EPM2A,RGS7BP,PHTF2,FBXO36,FRMD6,SOCS4" MicroRNA hsa-miR-296-3p:mirSVR_highEffct hsa-miR-296-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.24E-38 1.25E-34 7.52E-38 6.92E-37 93 504 "FMNL2,OSBPL1A,C1QTNF3,AMPD2,PPFIA4,PHF12,SUGT1P4-STRA6LP-CCDC180,CADPS,MARCH3,ATP2A2,ATP6V1G2,ADAM23,CAST,DLGAP1,TIGD7,SRSF11,SOCS6,CPNE6,CNTN1,AKAP6,CSF2RA,PDE4DIP,PNPLA8,KATNAL2,DCAF8,ZFYVE16,PITPNC1,JAKMIP2,DTNA,ECM2,EBF1,EDIL3,KLHL5,PAN3,EIF1,ENO2,CHST15,IP6K2,SMC2,FAM49B,ADAM28,TCERG1,RAB30,GNAO1,ZNF782,GRIN2D,TCEAL6,KIAA1755,IL6ST,ZNF667-AS1,MATN2,MBD1,IGSF11,PLIN1,STRN3,ING3,SEPT4,DRAM2,MAPK10,PTCH1,TMEM260,PTPRD,ZNF844,ZNF493,RBBP6,MSANTD2,KIF7,PBRM1,CCDC82,NEK11,RPL15,FBXW7,PTGR2,ATAT1,ATXN7,SCN8A,ASAP3,ABLIM3,ZNF334,MYO16,ERC1,POGZ,NKAIN2,TACR1,TRIO,AMACR,TBC1D15,ZNF28,NDRG4,ZNF138,FTSJ1,FZD3,CASC15" MicroRNA hsa-miR-507:PITA hsa-miR-507:PITA_TOP PITA 2.28E-38 1.27E-34 7.63E-38 7.02E-37 73 304 "ABR,ADRA1D,PCDH19,UNC79,AMPH,NCOA1,ATP2B2,DOCK11,BCL7A,JAZF1,HAP1,ZMYM4,B4GALT6,MYRIP,DZIP3,ERC2,RIMS2,LONRF1,EDIL3,KMT5B,EIF4G2,EIF5,RGS17,ERBB4,MED12L,KHDRBS3,GABRB3,B4GALNT1,GATM,AHDC1,PCDH17,DHRS4,BACH2,AGFG1,ZIC5,KCND2,MAP4,MBNL1,MEIS1,NEXMIF,NELL2,NPTX2,PCDH9,XRN1,CNTLN,PTPRD,USP47,REV3L,PCMTD2,FBXW7,SEMA6D,CHD9,DHX30,TET1,CPEB4,RCOR3,LMBRD1,SP4,HECW1,PEG10,ZC3H4,ADAMTS17,ADGRL3,TCF4,DMXL2,TRIM2,THRA,CSMD1,NR2C2,UBE3A,XRCC4,ZIC1,PHTF2" MicroRNA hsa-miR-557:PITA hsa-miR-557:PITA_TOP PITA 2.28E-38 1.27E-34 7.63E-38 7.02E-37 73 304 "ABR,ADRA1D,PCDH19,UNC79,AMPH,NCOA1,ATP2B2,DOCK11,BCL7A,JAZF1,HAP1,ZMYM4,B4GALT6,MYRIP,DZIP3,ERC2,RIMS2,LONRF1,EDIL3,KMT5B,EIF4G2,EIF5,RGS17,ERBB4,MED12L,KHDRBS3,GABRB3,B4GALNT1,GATM,AHDC1,PCDH17,DHRS4,BACH2,AGFG1,ZIC5,KCND2,MAP4,MBNL1,MEIS1,NEXMIF,NELL2,NPTX2,PCDH9,XRN1,CNTLN,PTPRD,USP47,REV3L,PCMTD2,FBXW7,SEMA6D,CHD9,DHX30,TET1,CPEB4,RCOR3,LMBRD1,SP4,HECW1,PEG10,ZC3H4,ADAMTS17,ADGRL3,TCF4,DMXL2,TRIM2,THRA,CSMD1,NR2C2,UBE3A,XRCC4,ZIC1,PHTF2" MicroRNA hsa-miR-4728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-38 1.48E-34 8.83E-38 8.13E-37 121 838 "XKR4,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,ADGRB2,SYNJ2,HAP1,CAMK2A,ISPD,CBS,SLC16A4,ARHGEF2,LONRF2,CDR1,SUMF2,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,RASA4,PLEKHA1,MRNIP,IGSF6,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,PADI2,AGBL5,ZNF491,SOWAHA,IGF1,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,MSI1,SAMD14,NBL1,NFIX,NOVA2,SLC11A2,TBC1D25,OGG1,ZNF713,GPR173,PFKFB3,CCSER2,RETREG2,PPP2R2B,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,CEP97,SH3TC2,IQSEC3,PRRT2,MORC4,PGBD4,EMID1,HES6,MYO18A,PEX26,PKNOX2,ZKSCAN3,IQSEC2,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,ERCC6L2,SSBP2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,PARP11,TMEM63C" MicroRNA hsa-miR-329-3p:Functional MTI Functional MTI miRTarbase 2.64E-38 1.48E-34 8.84E-38 8.14E-37 96 538 "ESYT2,TAOK1,ATP1A3,ATP1B3,ATP2A2,BACH1,CA8,KALRN,TBRG4,CRLF1,CFL2,B4GALT6,STOML1,CLTB,TBPL1,ANKRD44,MYADM,DNAL1,DBT,KLHL3,SV2B,MTX3,EGR3,EIF5,C8orf37,TUBD1,CHST15,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,PARD3B,CACFD1,ZNF496,GSTM5,HLF,HMGCR,USP51,C2orf72,SCIN,IL6ST,ITPKB,KCNB1,KLHL23,SYTL4,AFF1,HS6ST3,NEXMIF,TMOD2,PIK3R1,SNRK,PTCH1,RDX,ZMAT4,C12orf49,KIRREL1,SBF1,CSRNP3,SCN8A,GALNT10,TRA2B,WDR37,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,UNC5B,SS18,NECAB1,NAT16,GPRIN3,SIK3,SLC44A1,GALNT17,TIAM1,NACC2,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,WRN,NDRG4,CRB2,ZXDA,ADAMTS9,SIGLEC10,WNK3,FAM198A,SPATA13" MicroRNA hsa-miR-877:mirSVR_highEffct hsa-miR-877:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-38 1.62E-34 9.68E-38 8.92E-37 120 826 "CLK4,PCDH19,TAOK1,SMIM17,AMPH,ANK2,PKP4,UPRT,DDO,BCAS1,CACNA2D1,CALB1,THSD7A,KRIT1,USP6,C1orf52,CDO1,PLEKHB1,NDST3,NRXN3,CLCN3,C4orf33,RCHY1,PREPL,HINFP,SUSD5,PDE4DIP,ZSCAN23,RUBCN,RIPOR2,TMCC2,GRIN3A,DPYSL2,E2F5,FSD1L,C3orf18,EIF1,EPB41L2,EXTL2,ARMCX1,CEP78,FGF14,STAMBP,ATP2C1,CELF1,OGA,GABRG2,GCNT2,ZNF782,GRIA2,GRM8,MAP4K5,FRMD3,TNFAIP8L3,ZDHHC15,SHISA6,INPP5B,STXBP5,MAP2,SHC3,MMP16,MN1,NELL2,NRCAM,OCRL,LOC100128398,ZNF827,CNTN3,ETFRF1,SCHIP1,ING3,RASGEF1B,EPDR1,PSMA6,CNTLN,PTCH1,PTPRG,C1orf109,TTC13,ZNF615,MARCH1,REV3L,RGS4,RNASEL,SEMA6D,FNDC3A,CCDC92,FAM214B,SLC14A1,CPEB4,LMBRD1,SP4,NMNAT2,UNC5B,PEG10,TROVE2,SSTR1,TTBK2,KANK1,PRRC2C,SYNE2,CAMTA1,ADGRL3,ATMIN,TPCN2,USP32P1,FRYL,AP4E1,ASXL3,RIMBP2,AMACR,KCNE5,PRR18,TUBB2A,PLEKHH2,BCL2L13,TBC1D15,NAV3,PDSS2,PHTF2" MicroRNA hsa-miR-1276:PITA hsa-miR-1276:PITA_TOP PITA 3.51E-38 1.96E-34 1.17E-37 1.08E-36 77 343 "INTS2,KLHL13,PCDH19,SEMA6A,ALCAM,AMPH,DPP10,MAP4K3,APC,ATP1A3,FUBP1,MTMR3,JAZF1,SPAG9,CERS5,TMEM184B,RBM39,CNTNAP2,GAPVD1,ZFYVE16,MAML1,IP6K1,ELMSAN1,POM121,DLX1,GRIN3A,DRP2,DUSP9,STARD3NL,PAN3,MED12L,AGAP3,ARFIP1,SPIN1,TNRC6A,PRRC2B,PCLO,GRB10,FAM19A2,MARK1,MAT2A,LRP1B,KITLG,MITF,NEK1,OLA1,EPB41L4B,CEP41,PTPRD,OXR1,CARF,RORB,SNX22,PPM1E,KBTBD4,CPEB4,KDM4B,SOX11,CDK19,NFASC,MPRIP,NECAB1,SYNE2,SYT1,ANKRD12,CAMTA1,FBXW11,TCF4,PUM2,SIRT1,TRPS1,ZFP37,CADM2,NAV3,PHTF2,FRMD6,NETO2" MicroRNA hsa-miR-1250:mirSVR_lowEffct hsa-miR-1250:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-38 2.08E-34 1.24E-37 1.14E-36 95 529 "KLHL32,FZD9,AP2A2,RTL9,CC2D2A,UPRT,APOC2,ATP1A1,MYOM1,ADGRB3,NRP2,CFLAR,LDHD,KSR1,ARHGEF7,NAE1,CASTOR3,CA8,KALRN,DGKI,CNR1,SH2B1,RGS6,SOCS5,VAC14-AS1,PHF14,RIMS2,CCDC144A,MYADM,ARMCX4,ZNF804A,FAM107B,DTNA,DTNB,DNAJB6,PHF20L1,EGFR,COPS4,LRRC17,FDFT1,KAT8,OLFM1,FGF11,SPSB4,FGF13,NELFCD,POMT1,GCNT2,GPR37,BTN2A1,AGBL5,HSF2,SCIN,SFXN5,MAT2A,MKLN1,MYO7A,NOVA1,LOC100128398,ETFRF1,PCDH8,FA2H,RELN,WBP1L,PTPRO,SLC25A48,RGS12,PKNOX2,ANKRD36,LIMCH1,BDP1,MPRIP,KLHL7,ANKRD28,CAMTA1,MLST8,EXOC7,ADGRL3,TBCEL,IQCE,RPGRIP1L,ITGB3BP,PRRT1,KAT6B,TPM1,TPM2,ZFP37,CELF4,SPIRE1,UPF3A,RNF103,TMEM178A,FIP1L1,PHTF2,JPH3" MicroRNA hsa-miR-3162:mirSVR_highEffct hsa-miR-3162:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.86E-38 2.16E-34 1.29E-37 1.19E-36 104 632 "RALGAPA1,NDRG2,CCDC85A,BRAP,MTUS1,ZNF578,ALCAM,IGDCC4,SPTBN4,MYOM1,TTLL9,BACH1,BCS1L,NRP2,CASTOR3,CALM1,SLC25A14,CBLN1,CD38,LRBA,LARGE1,NRXN3,PPT2,TPP1,FBXO7,COL11A2,ABI3BP,TOGARAM2,SEC31B,RBM39,NCOR1,CLIP3,DOCK4,HDAC9,ARHGAP24,DCAF8,ZBTB24,MYEF2,GRIN3A,DTNA,MAMLD1,SEZ6L2,EDNRA,FAM13A,KMT5B,MRNIP,EPHB1,IGSF6,RRAGB,EYA1,FGF12,TMEM164,PDLIM5,TUBGCP4,CYP46A1,RUNDC3A,HPGDS,PCLO,KAT7,RASSF8,VSIG4,NKD1,KCND1,MAP2,MEIS1,CNOT4,NPR2,PCSK1,EPB41L4B,RAP1GDS1,ROGDI,KHDRBS2,SLC25A36,RIC8B,ATAT1,FNDC3A,SEC31A,PPP4R3A,GKAP1,RCOR3,MBD5,TMCC1,UNC5B,DBNDD2,AGTPBP1,PCDHB4,FRYL,HIF3A,AP4E1,AKTIP,MTMR14,TMEM9,UBTF,PLEKHH2,BCL2L13,RICTOR,KCNT2,CELF4,POLR3H,CADM2,SLC17A7,FAM13C,UBE3B,IFT88" MicroRNA hsa-miR-326:mirSVR_highEffct hsa-miR-326:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.68E-38 2.62E-34 1.56E-37 1.44E-36 109 693 "RALGAPA1,DGCR6,EMILIN3,SYS1,PLEKHH1,ADORA2A,RNF150,CASKIN1,FAM135A,DOC2A,CDC42BPA,TMEM108,ALDH7A1,ATP6V1G2,BARD1,SEC11C,RGS9,NRP2,KSR1,RCBTB2,AKAP6,CSF2RA,LRIG1,OSBPL3,APPL1,GIT2,HEPH,USP3,MED12,DTNB,ABCC5,DNM1L,EBF1,ASB3,C3orf18,SRRM1,ERBB2,CEP78,PPP1R1B,FGF1,FGF11,FGFR1,ANKFY1,MSANTD4,TPPP3,ZNF274,DISC1,IGSF5,WASHC2A,USP19,GGT7,HPGDS,ZNF638,GPD2,BTN2A1,ZBTB49,IDH3B,ZNF181,LRRTM1,KIF5A,MAT2A,MEST,MYO7A,VWA2,SLC11A2,PALM,CYTL1,PLEC,PURG,SCHIP1,SEPT4,PKIA,CNTLN,C1orf109,NKAIN1,SLC25A48,OXR1,EXD2,RORB,DGLUCY,TNFRSF19,ZFP2,SEC14L1,FNDC3A,SLC22A4,ANKRD36,SNRPN,ZSWIM8,SSPO,ERBIN,ELOVL4,ARC,RNF216P1,ITGB3BP,AP4E1,CDH22,ENHO,CDK20,UBE2H,UGT8,MTCH1,VLDLR,ZNF781,ELFN1,DHX33,PPP1R3F,SMIM8,CASC15,ACTR3B" MicroRNA hsa-miR-24-2*:mirSVR_lowEffct hsa-miR-24-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-38 3.06E-34 1.82E-37 1.68E-36 115 768 "OLMALINC,OSBPL8,SYT13,LRCH2,FGD2,APAF1,APC,TNRC6C,CDC14B,IGDCC4,SPTBN4,STK33,RIPK1,PTBP2,CAMK2A,CAST,P2RX6,ARHGEF2,LRRFIP1,SEC31B,RBM39,SNCAIP,DZIP3,ARHGAP32,IP6K1,HEPH,RHOBTB1,EXOG,DNAH9,EDIL3,CERCAM,RCAN2,ENPP6,RRAGB,ABCA8,FAM198B,CEP78,FGF13,IQCG,ATP6V1H,ZNF605,DISC1,DBF4,TNRC6A,LILRB4,GPD1,FAM107A,ARHGAP36,ELOVL5,LRRC75A,GAREM2,IL6ST,TTYH2,HECTD2,MEIS1,SCAMP5,MN1,MPP2,N6AMT1,HNRNPM,NPTX2,P2RY1,GLIPR1L2,GPR173,ZDHHC8,GPSM2,NLE1,LRP12,PPP2R5E,PRKAB2,TMEM104,PTN,PTPRE,RAD51D,RDX,SLC25A36,RORB,NEK11,KIAA0895L,ABCA11P,KCNIP3,ZNF568,TRAPPC13,ATXN2,PEAR1,FNDC3A,PEX26,CCDC88A,KBTBD4,LIMCH1,DOP1A,ZC3H13,DBNDD2,SPTB,ZBTB43,NFASC,PBLD,ELOVL4,ADAMTS17,SYN2,SYP,SYPL1,TMPO,FAM124A,TP53BP2,CHST5,TRIO,TRPS1,PPIL6,SSBP2,FLRT2,GUSBP1,ZNF154,MAP3K12,FZD3" MicroRNA hsa-miR-22:PITA hsa-miR-22:PITA_TOP PITA 5.70E-38 3.19E-34 1.90E-37 1.75E-36 67 255 "EMILIN3,FMNL2,ADCY6,ADRA1B,ALCAM,PDZD4,DOC2A,DPP10,USP37,NCOA1,BACH1,WASF1,CABP7,KALRN,CAMK2G,VXN,ZMYM4,FOXN3,RIMS4,PLCXD3,HDAC4,C2CD2L,ALKBH8,SNAP91,SEMA3D,EMX2,EPB41L2,ERBB4,ETV1,FAM49B,FUT9,MEGF11,MTHFD2,GATM,GPR162,TNRC6A,KAT7,SMAP1,INPP5B,MAT2A,MEIS2,NEFM,NELL2,NOVA1,OLA1,SNRK,USP47,DPF2,RIC8B,FBXW7,HUNK,CHD9,BTBD3,SEPHS1,EPC1,KDM3A,PRRC2C,ANKRD12,SATB2,SYNE1,SIRT1,ZNF106,TIAM1,KAT6B,PDSS1,KCNE5,KAT6A" MicroRNA hsa-miR-617:mirSVR_highEffct hsa-miR-617:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-38 3.41E-34 2.03E-37 1.87E-36 105 647 "KCNH8,SYN3,PWWP2A,MTUS1,ZNF578,ABCD2,SUGT1P4-STRA6LP-CCDC180,DDO,SYNJ2,USP6,ZMYM4,NDST3,LETMD1,NECTIN3,CREM,AKAP12,HAPLN1,GDA,SOCS5,DCAF4,DOCK4,ARHGAP32,KCTD8,DMD,DTNA,ABCC5,NCALD,ADGRV1,CLVS1,CHST15,GORAB,FGF1,PRKAG2,FOXF2,SLC37A3,CHL1,ACSS1,TCERG1,RAB30,MAP7D2,CNTRL,PLCD4,AP4S1,PSIP1,RNFT2,INSYN1,HNMT,CFAP126,ZNF181,ZNF678,MAN2A2,AQP11,MYCN,OGG1,PCDH9,GPR85,PURG,MAPK9,PIGG,PTX3,FAM66C,RASGRF2,TMLHE,PNMA8A,CCDC102B,RPE,SNX22,EPHA10,ATAT1,R3HDM2,SYBU,KANSL3,ARHGEF40,SLC11A1,SLC14A1,MYH15,ANKRD36,SNRPN,PDZD2,FNBP1,UHRF1BP1L,ATP10B,CLSTN2,KANK1,SULF2,STXBP1,NECAB1,VPS13A,FBXW11,ZEB1,DOCK9,USP32P1,VWCE,SIRT1,C18orf54,AP4E1,ZNF106,AKTIP,SLC44A1,RUSC1,ZNF19,LYPD6,UBE3B,HNRNPA3,ADAMTSL3" MicroRNA hsa-miR-1277-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-38 3.71E-34 2.20E-37 2.03E-36 103 624 "ABCF1,FMNL2,ADD2,ZNF608,TAOK1,FAM135A,MARCH3,NUMB,FUBP1,CA8,CA12,THSD7A,RUNX1T1,CFL2,C4orf33,QKI,TBPL1,ANKRD44,UBXN2A,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,PITPNC1,SPATA2,CDON,CPEB2,YAF2,GOLGA7,CERCAM,RCAN2,FER,POLR1B,TRMO,ZBED3,MSANTD4,MPP6,GCK,MMADHC,PPARGC1A,COPS8,TPPP,BVES,INSYN1,BACH2,USP51,NEGR1,IGF1,ZIC5,SCIN,IL6ST,ZNF678,KCNB1,KLHL23,KCNN3,L1CAM,SMAD9,MMP16,NEXMIF,NCAM2,NTRK3,PIK3R1,XRN1,PURG,PSAT1,PPP1R1A,PPP2R5E,EPDR1,SNRK,CEP97,PRIMA1,CARF,AP1AR,CSRNP3,ZHX3,ERC1,NECAB1,PRRC2C,SYP,SYPL1,TRIM2,DOCK9,SIK3,ZMAT3,CSMD1,RGMB,NR2C2,TRPS1,OSBP2,CCDC14,KCNK12,SMARCAD1,SLC30A4,MAP3K12,ZXDA,CADM2,SLC38A1,EVI5,STOX2,FAM182B,KAT6A" MicroRNA hsa-miR-1271:PITA hsa-miR-1271:PITA_TOP PITA 7.32E-38 4.09E-34 2.43E-37 2.24E-36 78 356 "XKR4,ADCY6,SLC24A4,SEMA6A,ALK,OGT,LRCH2,C6orf89,DPY19L3,ADGRB3,MTMR3,JAZF1,CACNA1G,LDLRAD4,CACNB4,THSD7A,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,CLTC,MAP4K4,CNN3,CABP1,MYRIP,CDC42BPB,LRIG1,RIMS4,ERC2,ARHGAP24,TM9SF4,E2F5,SNX29,EIF5,GPHN,FOXF2,FAM49B,ST6GALNAC3,FYN,B4GALNT1,PCDH17,SPIN1,ZHX1,MBNL1,CHIC1,MITF,NEXMIF,NOVA1,IGSF11,GPR85,PIK3C2A,EPB41L4B,SH3KBP1,ZFHX4,MCMBP,MRAS,FAM81A,PPP4R3A,BTBD3,CPEB4,MYO16,SS18,KLHL7,COBL,TACC1,CAMTA1,FBXW11,TBL1X,TCF4,SIN3B,ZIC2,TMEM198,ZFAND5,NAV3,ST7,JMJD1C,GAN" MicroRNA hsa-miR-4329:mirSVR_highEffct hsa-miR-4329:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-38 4.20E-34 2.50E-37 2.30E-36 100 590 "CC2D2A,SMIM17,BIN1,VAT1L,TNRC6C,ARNTL,ZBTB10,NUMB,SGCE,CACNA1G,RCBTB2,CHGB,COL4A5,CDC42BPB,GDA,ARHGEF10,DOCK4,MAML1,DGKB,DGKG,BRINP1,DBI,ALKBH8,DOCK2,DPYSL2,FCF1,SUGP2,GOLGA7,STARD3NL,RCAN2,ENPP6,PIPOX,EXTL2,FGF11,FGFR1,TMEM164,ATP13A4,NELFCD,ZNF605,CGREF1,NEURL4,ZMAT1,GALNT15,B4GALNT1,SIGLEC8,ZNF559,DISC1,TUBGCP4,ADAM28,GHR,CBX1,MAP7D2,IDH3B,CLEC18A,MARK3,MBD1,MBNL1,MBP,ADAM22,NDP,NTRK3,CHAMP1,PDZRN4,LRP12,ING3,DRAM2,PPP1R1A,WBP1L,SH3TC2,FAT4,RFX3,ZDHHC4,CCDC102B,SEC14L1,AMBRA1,CHD9,FHOD3,PPP4R3A,MBD5,BDP1,KDM4C,DMXL2,PCDHB7,FRYL,ITGB3BP,AP4E1,BEX4,SMUG1,SSBP2,TUBB2A,USP1,RICTOR,TRIM9,NDRG4,MPPE1,NELFE,UBE3B,HNRNPA3,KLHDC1,SOCS4" MicroRNA hsa-miR-1201:mirSVR_highEffct hsa-miR-1201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.76E-38 4.34E-34 2.58E-37 2.37E-36 97 556 "LGR5,LINC00173,CDK13,MARK4,NCOA1,RGS9,PTBP2,CAST,DLGAP1,CNOT8,TPP1,LETMD1,CREM,HAPLN1,HINFP,NCOR1,CS,ARHGEF10,DOCK4,GAPVD1,KIAA0586,DGKB,SV2B,NYAP1,DMTF1,DPP6,PDCD6IP,DTNA,ANKRD46,RASGRP1,GPHN,CEP85L,EXTL2,TAOK3,UFM1,CGREF1,OGA,DISC1,NEU3,HPGDS,ZNF638,FERMT2,GRIN2C,RABL2A,TNFAIP8L3,IRF8,RBPJ,LIMS1,MBNL1,MEIS1,POC1B,MMP16,MYO6,NFE2L2,DNHD1,NRCAM,OPA1,PCSK5,GPR85,ZNF655,XRN1,PURG,TRHDE,SCHIP1,RETREG2,APTX,RBBP6,PBRM1,CCDC102B,RMI1,SEMA6D,CSRNP3,TNFRSF19,ST6GAL1,ANKRD6,CPEB4,DOK5,TEX2,POGZ,ELOVL4,TTBK2,PRRC2C,PCDHB4,ZFPM2,ITGB3BP,AP4E1,AMACR,TTTY15,SGK3,ZNF45,FAM47E,FBXO36,CASC15,TRAM2-AS1,KLHDC1,DPF3,ST8SIA2" MicroRNA hsa-miR-625*:mirSVR_highEffct hsa-miR-625*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.03E-38 4.49E-34 2.66E-37 2.45E-36 101 602 "RALGAPA1,DPY19L2P4,AP2A2,OSBPL8,LRCH2,PKP4,LGR5,ARNTL,MTMR2,CACNA2D1,SLC25A14,LRRFIP1,QKI,AKAP7,RCHY1,ANKRD44,SOCS5,PHF14,GREB1,HDAC9,DGKB,YTHDC1,ZNF804A,DDX46,PLPPR4,DMD,EDNRB,EIF4G2,PLEKHA1,LRRC17,SRRM1,DENND4A,ETV1,RRAGB,SCML2,ZSCAN30,PCYOX1,STAU2,ARFIP1,HTATSF1,FERMT2,WDFY3-AS2,GPD2,ATP2B1-AS1,FAM19A2,PAXBP1,MAT2A,MEST,MXI1,NF1,GPR137C,GPR85,PURG,PPM1B,GRAMD1C,PTN,PTPRD,ZNF793,RAP1GDS1,RBBP6,RDX,SETD5,CARF,CCDC25,RORB,BAALC,SAFB,SLC2A5,SEPHS1,ATF7IP,CPEB4,MYH15,KIF13A,PEG10,PBLD,CLASP2,CLSTN2,SSTR1,ZSCAN29,SEPT8,SULF2,COBL,FAM208A,SATB2,PCDHB3,ITGB3BP,RIMBP2,RGMB,RUNDC3B,ANKRD20A2,FLRT2,VLDLR,ZNF781,ZNF28,ZNF142,EMSY,CADM2,WNK3,RGS7BP,NETO1,RNF146" MicroRNA hsa-miR-3196:mirSVR_lowEffct hsa-miR-3196:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.03E-38 4.49E-34 2.66E-37 2.45E-36 101 602 "RNF157,PWWP2A,BEGAIN,EP400,CDK10,MADD,SPTBN4,ARHGDIA,ARHGDIG,ATP1A3,CARMIL3,KSR1,KALRN,ARHGEF1,ENTPD2,NUMBL,NRXN3,CCDC151,FAM149A,NRG2,ZNF385A,ANKRD44,NCOR2,GDA,SLITRK5,DCTN1,RUSC2,DTNB,ANKRD46,CELSR3,EIF1,MTSS1L,EPHB1,REEP2,PTK2B,KAT8,BAIAP2,AGAP2,ZNF274,ALDH1L1,TUBA8,ZNF276,STMN2,GRB10,C1QL4,LINGO1,PACSIN2,ATXN2L,HMGCL,IDH3A,LRRC25,KNDC1,L1CAM,PPM1L,XRRA1,MSI1,RTL5,FXYD7,DNHD1,OGG1,PDE4A,PFKFB3,NLGN3,CCSER2,PLEC,PILRA,POLR2F,VSTM2L,CNNM2,SUSD4,PRRT2,ATAT1,STX1B,ARX,MYO18A,SLC12A4,SNRPN,TSPYL2,MCF2L2,STX1A,SYN1,ARC,SYN2,EXOC7,PDLIM2,TCF4,NEU4,NAT16,TNS2,TMEM121,TMEM9,PIK3R5,NPL,C9orf85,SMUG1,CLEC2L,ZIC2,PRDM8,TMEM178A,GJC2,JPH3" MicroRNA hsa-miR-7106-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.45E-38 4.73E-34 2.80E-37 2.58E-36 116 784 "XKR4,RNF157,ADD2,PLEKHH1,CASKIN1,SORCS2,TXNDC16,TRMT9B,PHF12,AQP6,PRX,ARRB1,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,CBS,METTL6,SLC16A4,LONRF2,CDR1,SUMF2,LETMD1,CRMP1,CRY2,NCOR2,RGS6,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,DNAH9,SLC29A4,PHC2,TMTC1,RASA4,EIF4G1,PLEKHA1,ING4,MRNIP,IGSF6,TRMO,CELF1,BRSK1,TRAF3IP2,DISC1,SRCAP,AHDC1,CRCP,GLYR1,GLUL,STARD3,GNG4,PRRC2B,ZNF496,BVES,IRAK3,AGBL5,ZNF491,SHISA6,IGF1,IBA57,KCND1,KCNH2,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDE4A,PFKFB3,RETREG2,POLR2F,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,EMID1,RXRA,FNIP1,HES6,MYO18A,TRIM67,ZKSCAN3,SP2,MCF2L2,CAMTA2,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,NACC2,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,URM1,PARP11,TMEM63C" MicroRNA hsa-miR-24-3p:TargetScan hsa-miR-24-3p TargetScan 1.00E-37 5.61E-34 3.32E-37 3.06E-36 98 569 "ADD2,RNF150,LRFN2,PCDH10,OGT,GAS7,MARK4,CCDC74A,NCOA1,ATP2A2,NRP2,MTMR3,HAP1,CAMK2B,RHBDL1,SCARB1,ENTPD6,MAGI1,CLCN3,CNTFR,AKAP5,CRY2,MROH8,CSF1R,ERC2,RIMS2,MATR3,KLHL3,GUCD1,FAM107B,EXOG,DTNA,FAM78B,KCTD3,EIF5,REEP2,SCML2,DLC1,FCGRT,FGF11,FGFR3,AMOTL2,GAD1,PCDH17,LYVE1,RNF165,BVES,KCNB1,KIF2A,GPR155,MATN3,CHIC1,MEIS2,SCAMP5,MMP16,GIT1,DBNL,MXI1,NEFM,NFIX,NOVA2,NPTX1,PDE3A,MAPK7,PIGG,PTPRD,GTDC1,CYB561D1,KCNIP1,GALNT10,FERMT1,MYO18A,DHX30,ATF7IP,MAPKBP1,MBD5,ARHGAP26,DDN,NFASC,NEK4,MMS19,PDLIM2,CRTC1,MTMR14,CBX5,KAT6B,RASD2,ELP5,PPIL6,PLEKHH2,KLC2,NDRG4,REEP1,POLR3H,EML6,DHX33,GAL3ST3,KAT6A" MicroRNA hsa-miR-4309:mirSVR_highEffct hsa-miR-4309:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-37 5.71E-34 3.38E-37 3.12E-36 103 627 "NCKAP5,SYS1,PLEKHH1,HECW2,CC2D2A,AMT,MYH7B,PKP4,APC,MARK4,ADAM23,CFLAR,BMP7,KALRN,KRIT1,ARHGEF2,DIS3L,CPNE6,RAB33A,FBXO7,CNR1,IGDCC3,SLC35F1,HAPLN1,SNCAIP,RGS6,VCAN,UBXN2A,KATNAL2,GAPVD1,ARHGAP24,SCRN1,ARMCX4,DDX46,DTNA,EBF1,EDN3,FRY,TMEM35A,SRRM1,DENND4A,IGSF6,FAM198B,FGF12,POMT1,OGA,ERAP1,KIAA1841,TCERG1,TDRKH,GRIA2,RABL2A,IRAK3,RASSF8,SMAP1,NME9,LAMA2,MAP2,MAT2A,NPTX2,PCSK5,ENPP2,FAM216A,PMP22,STRN3,EPB41L4B,PKIA,TMEM260,ACSM5,ACSS3,ZNF793,SUSD4,FIGN,NUDT11,GLDN,ATAT1,SHC4,FNDC3A,ATF7IP,SNAP25,MBD5,SNRPN,PEG10,MCF2L2,SEPT8,CAMTA1,DOCK9,HIF3A,FAM200B,AP4E1,TMPO,SYNPO2,KCNE5,MTCH1,CCDC14,P2RY12,GUSBP1,ZIC1,LYPD6,CELF4,PDSS2,FBXO36,CASC15" MicroRNA hsa-miR-362-3p:Functional MTI Functional MTI miRTarbase 1.15E-37 6.41E-34 3.79E-37 3.49E-36 95 536 "ESYT2,TAOK1,ATP1A3,ATP1B3,ATP2A2,BACH1,CA8,KALRN,TBRG4,CRLF1,CFL2,B4GALT6,STOML1,CLTB,TBPL1,ANKRD44,MYADM,DNAL1,DBT,KLHL3,SV2B,MTX3,EGR3,EIF5,C8orf37,TUBD1,CHST15,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,PARD3B,CACFD1,ZNF496,GSTM5,HLF,HMGCR,USP51,C2orf72,SCIN,IL6ST,ITPKB,KCNB1,KLHL23,SYTL4,AFF1,HS6ST3,NEXMIF,TMOD2,PIK3R1,SNRK,PTCH1,RDX,ZMAT4,C12orf49,KIRREL1,SBF1,CSRNP3,SCN8A,GALNT10,TRA2B,WDR37,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,UNC5B,SS18,NECAB1,NAT16,GPRIN3,SIK3,SLC44A1,GALNT17,NACC2,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,WRN,NDRG4,CRB2,ZXDA,ADAMTS9,SIGLEC10,WNK3,FAM198A,SPATA13" MicroRNA hsa-miR-219-1-3p:mirSVR_highEffct hsa-miR-219-1-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-37 6.52E-34 3.86E-37 3.55E-36 113 749 "CCDC85A,OGT,PARG,STK33,JAZF1,CALM1,CLCN3,FBXO7,CNTN1,RCHY1,ZNF385A,SLC35F1,RNF14,C1QL2,CS,SEC24C,VCAN,CYBB,RIPOR2,CENPL,KIAA0586,DGKB,ZBTB24,DDX46,RHOBTB1,WDR20,EDN3,PHF20L1,C8orf37,GORAB,SEC24B,POLK,ATP2C1,NSG1,FYN,MEGF11,ERAP1,TUBGCP4,ZNF638,DCLK2,GRB10,PLCD4,FAM19A2,BVES,ZHX1,MIER3,IGF1,IL6R,ITGAM,JAK2,KCNN3,CREG2,KTN1,LAMP2,MBNL1,MEIS2,SRSF12,MEST,XRRA1,ZNF680,NF1,OXTR,CNTN3,PDE4D,GNG2,TRHDE,PPM1B,PPP3CC,HYDIN,SAMD9,PIGG,ZIK1,PTPRB,EML5,PTPRE,ZNF493,ZDHHC14,RIC8B,ZFHX4,ROBO1,YY1AP1,SPIN3,LRRK2,ABCA11P,SEMA6D,CNKSR2,KBTBD4,ZFP1,PDZRN3,PDZD2,HECW1,RBM26,NFASC,ITPRID2,ZNF302,SS18,TTBK2,SYT1,MLST8,SLC19A3,FAM200B,ICAM5,TLR4,CCDC136,ZNF781,XPO1,ZNF708,CELF4,FAM47E,AMN1,IFT88,LAS1L,FAM198A" MicroRNA hsa-miR-432*:mirSVR_highEffct hsa-miR-432*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-37 6.58E-34 3.89E-37 3.58E-36 100 593 "XKR4,PLEKHH1,HECW2,TXNDC16,PCDH10,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,PPFIA3,DYNLL1,TMEM108,RIPK1,ADGRB3,BMP7,SYNJ2,CALB2,CHGB,CHN2,PLEKHB1,PLAA,C4orf33,IGLON5,COL9A1,SLC4A8,RTTN,CRHBP,LRRC3B,OSBPL3,DCAF8,NR1D2,DRP2,EDN1,ANKRD46,PHF20L1,EGFR,MBNL2,EXTL2,RACK1,RASL10A,ST6GALNAC3,ZNF234,MSTN,GPR162,GPD2,PCLO,GRIN2C,MAN1B1,TNFAIP8L3,HMGCL,SMAP1,KCNJ5,KIT,KPNA5,MEIS2,ADAM22,MYT1,SFR1,PDE1B,SH3KBP1,TATDN3,WDR25,PTK2,PTPRH,PTPRO,ZNF615,ENOX1,RASGRF1,CRTAC1,GTDC1,ZNF532,PNMA8A,ZNF568,NCBP3,LRFN5,TNFRSF19,CHD9,SLC8A1,BTBD7,ATF7IP,MAST1,MBD5,CMTR2,HECW1,ATP10B,NKAIN2,MPRIP,CAMTA1,ZFP90,CLASP1,SIK3,FAM200B,DICER1-AS1,SSBP2,LAT2,TRIM9,EML6,MEIS3,SLC30A3,CADM2,NAV3" MicroRNA hsa-miR-608:mirSVR_highEffct hsa-miR-608:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-37 6.96E-34 4.11E-37 3.78E-36 106 664 "VWA5B2,NDRG3,ADGRF5,SPOP,MARCH4,ZFAT,OGT,PHF12,SEMA4G,ARRB1,NCOA1,ATP1A1,CARMIL3,AZGP1,MPDZ,NRP2,CACNA1B,CALB2,CBLN1,LDB2,CD86,ENTPD2,ZMYM4,DLGAP1,EPS15L1,TPP1,IGLON5,WHRN,CLIP3,LRRC3B,CYBB,HDAC9,GAPVD1,RIPOR2,DGKG,DBN1,PITPNC1,RAB39B,EBF1,EDNRA,EGFR,ELN,NRN1,F5,ZSCAN30,SYT3,COQ5,HVCN1,CELF1,GABBR1,TRAF3IP2,B4GALNT1,IQGAP2,ERAP1,SEPT9,GPR162,TTBK1,GLI2,PRUNE2,DIDO1,PLCD4,ZNF496,FAM107A,SMAP1,LRRTM1,KCND1,KCNH2,KCNN1,TM6SF1,PPM1L,MOV10,GIT1,PFKFB3,PNMA3,KANSL1,MAPK3,SLC26A11,KLK6,PSD,CCDC40,MSANTD2,GTDC1,KIRREL1,NCBP3,PPP4R3A,SLC11A1,ATF7IP,SNAP25,MBD5,PBLD,DIP2A,NSFL1C,SLC37A2,SYT5,SYNE1,PCDHB9,NSD1,HIF3A,MTMR14,RIMBP2,TPM2,LGI4,TMEM198,SIGLEC10,RTN4,PRRT4" MicroRNA hsa-miR-182*:mirSVR_highEffct hsa-miR-182*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-37 7.25E-34 4.28E-37 3.94E-36 96 548 "KLHL32,ADCY8,PLEKHH1,KLHL13,CC2D2A,SRPX,CARNS1,EIF4G3,SCAPER,MTMR2,TIGD7,CFL2,FAM189A2,ARMC8,SLC4A8,CREM,ENTPD4,CRY2,PNPLA8,CYBB,LIN54,MATR3,DGKB,DDX46,FAM107B,DTNA,FAM78B,AASDH,RCAN2,RASL12,CLVS1,FAM198B,SCML2,DLC1,SLC9B2,POLK,NELFCD,RAPGEF6,ERAP1,ZNF559,GATM,PCDH17,GHR,TCERG1,GNAO1,GRIK4,RNFT2,ELOVL5,HNMT,NEGR1,FAM95B1,IL6ST,ZNF678,KIF5A,MAP4,MXI1,LYRM9,NF1,NUCB2,OGG1,CNTN3,RETREG2,TATDN3,PPP3CA,TTC13,OXR1,RADX,UBR7,ZNF532,ATAT1,SH3GL3,FERMT1,SHC4,FNDC3A,CNKSR2,SLC12A2,MTERF2,TMCC1,SPART,MPRIP,SYN1,TMEM150C,ZFP90,SYNE1,DOCK9,SYNPO2,PPIL6,TTC3,ZNF709,KCNT2,SLC30A4,RNF103,SMIM8,HNRNPA3,PHTF2,FRMD6" MicroRNA hsa-miR-1537:mirSVR_lowEffct hsa-miR-1537:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-37 7.51E-34 4.43E-37 4.08E-36 95 537 "METAP1D,PSMG3-AS1,PITPNM2,MARK4,ATP2B2,SLC2A11,ADGRB3,BARD1,ARHGEF7,CALB1,RUNX1T1,CLDN10,LDB2,LARGE1,CACNA2D2,NRXN3,FAM19A5,ARMC8,FAM149A,MYRIP,C2CD2,KIAA0408,KIAA0319,TMCC2,SEC16A,DPH1,EDNRA,CNNM1,SUGP2,VPS13B,ETV1,EZH1,TAOK3,STRADA,FDFT1,SLC37A3,CAMKK2,STAU2,ERAP1,DISC1,SRCAP,AHDC1,LUZP2,FERMT2,STMN2,BVES,SOX21,GUCY1B1,HSF2,INPP5B,KTN1,LSS,LYPLAL1,AQP11,MBP,MIA2,MITF,MMP16,NTRK2,OCRL,OXTR,PCDH8,PKD1,PMP22,TRHDE,MAPKAP1,LRP12,ING3,EPB41L4B,FA2H,VSTM2L,PTPRE,OXR1,CCDC25,ELP2,RPL15,RPS20,FHOD3,SLC22A4,NMNAT2,ZNF423,LARP4,NECAB1,ASTN2,DICER1,SIRT1,TIAM1,RASD2,TSC1,RPRM,CLIP2,ZIC2,RNF103,FAM47E,UBE3B" MicroRNA hsa-miR-624:PITA hsa-miR-624:PITA_TOP PITA 1.50E-37 8.39E-34 4.95E-37 4.56E-36 69 276 "ABR,PCDH19,OSBPL1A,OSBPL8,DPP10,CACNA1A,USP6,ZMYM4,SOCS6,QKI,GDA,ERC2,PLCXD3,PUM1,DOCK4,ALKBH8,MAMLD1,ABCC5,KMT5B,SEMA4D,NBEA,CELF1,OGA,FYN,MEGF11,GABRB3,CPLX2,GFRA2,PCDH17,NEGR1,IGF1,RBPJ,MBNL1,MPP2,MYCN,NEK1,NTRK3,CHAMP1,OPA1,PPP3CA,KANSL1,TMEM255A,ROBO1,ROBO2,AP1AR,SALL1,SEMA6D,CPEB3,ATF7IP,FNBP1,SPART,NKAIN2,SS18,TTBK2,ANKRD28,MTCL1,EXOC7,ADGRL3,TBL1X,TCF4,SATB2,TRIM2,SYNE1,PUM2,FRYL,FLRT2,ZBTB38,POLR3H,JMJD1C" MicroRNA hsa-miR-191:mirSVR_lowEffct hsa-miR-191:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-37 8.81E-34 5.19E-37 4.78E-36 95 538 "ABR,ASPHD1,SYS1,ADCY8,ZNF608,SEMA6A,SYT13,LRCH2,PHF12,CASK,EIF4G3,ATP2B2,BBS2,SCAPER,MYRF,CALM1,PTBP2,KRIT1,MTMR7,NRXN3,PPT2,CNN3,AKAP5,GDA,EARS2,FBXL5,SACS,FAM107B,GRIN3A,PHC2,FRY,GORAB,SEC24B,SLC37A3,PDLIM5,ATP6V1H,ZNF274,SPIN1,GLYR1,RAB30,TOX3,ZNF638,PCLO,GUCY1B1,AGBL5,CELF5,TTYH2,LAMP2,LIFR,MAP4,MARK3,MEIS1,MSI1,TAGLN3,NELL2,NOVA1,DNHD1,NPTX2,CHAMP1,OXTR,PCDH8,TMOD2,PURG,MAPKAP1,NWD1,ENOX1,RASGRF1,GTDC1,ZNF532,SETD5,PNMA8A,NEK11,GLDN,NCBP3,ZNF331,SCN8A,SHC4,SLA,SLC6A8,SLC12A2,SMARCA4,KANK1,JMJD6,USP22,ZFPM2,SLC44A1,TSN,TTTY15,P2RY12,ZIC2,EML6,FAM13C,UBE3B,FAM219B,FXR1" MicroRNA hsa-miR-3197:mirSVR_lowEffct hsa-miR-3197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-37 1.04E-33 6.11E-37 5.62E-36 104 643 "ABCF1,SYS1,GALNT16,ADORA2A,HACE1,WDR35,LTBP4,CDK10,CASK,SPTBN4,MARK4,ADAM15,RGS9,BMP7,SYNJ1,CABP7,HAP1,PPT2,NGEF,ARHGEF6,IQCK,LETMD1,NCOR2,ARHGEF10,DLX1,SHANK1,DPH1,ACOT8,SIRPB1,EVL,RASL10A,ATP6V1H,B4GALNT1,DISC1,LRRC37A6P,CPLX1,GFER,TTBK1,STARD3,GPT2,GPER1,GRM2,ZBTB49,RABL2A,SHISA6,CELF5,GAREM2,KNDC1,KCNN1,L1CAM,MBP,MYO7A,CCDC13,ZNF827,PCSK5,PDE4A,PFKFB2,ZFYVE21,NKAIN4,PPP5C,WBP1L,TUG1,RASGRF2,PRRT2,RFX2,RIC8B,CCDC25,RPS6KA2,EMID1,FAM192A,TNFRSF19,SH3BGR,FUZ,SHMT2,SLC6A8,SLC11A1,SMARCA4,SMARCC2,USP33,MYCBP2,KDM4C,SSPO,SEPT3,SYP,SIN3B,CLASP1,TNS2,AP4E1,TMEM9,TMPO,STXBP4,KCNE5,UBTF,TOM1L2,KLC2,GUSBP1,LGI4,ZNF138,REEP1,GDPD5,PARP11,PDSS2,UBE3B,LAS1L" MicroRNA hsa-miR-3183:mirSVR_highEffct hsa-miR-3183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.90E-37 1.07E-33 6.27E-37 5.77E-36 118 816 "CLK4,BRAP,SLC24A4,TNRC6C,USP37,SFMBT2,STX16,ADAM23,BARD1,ARHGEF7,PTBP2,ZNF501,ZMYM4,CNOT8,ARMC8,COX4I1,SEC31B,C2CD2,SH2B1,GALNT9,SOCS5,CCDC144A,GAPVD1,PITPNC1,DDX46,ALKBH8,SNAP91,RAB39B,FAM78B,DNM1L,EDN3,EDNRB,EGFR,KMT5B,EPHB1,ENPP6,ETV1,TLR7,EXTL2,RACK1,PRMT5,ZNF589,CSPG5,DOT1L,B4GALNT1,RUNDC3A,BRD8,MAP7D2,ADGRA3,TDRKH,LILRA2,GRIA2,CLASRP,RNFT2,MAP4K5,UBE2QL1,HNF4G,IRF8,IGF1,KIAA1755,SCIN,KCNN2,LIMS1,PIK3AP1,COL28A1,TAGLN3,MXI1,NF1,PCBP3,ANKRD16,MAPKAP1,EPB41L4B,MAPK4,GRAMD1C,HYDIN,BDNF-AS,PTPRB,SLC25A48,RIC8B,CCDC82,EPHA10,ATXN7,SMPD3,SUPT20H,CPEB3,CNKSR2,SLC22A4,RCOR3,IFT122,LIMCH1,SNCA,CMTR2,SNRPN,SP4,KDM4C,NXT2,PLCB1,CAMTA1,FBXW11,SYNE1,NAT16,SLC44A1,BHLHB9,RGMB,SYNPO2,METTL3,STXBP4,UBE3A,TOM1L2,VLDLR,WIPF1,XPO1,ZNF74,ANKS1B,ADAMTS9,PPP1R3F,PDSS2,CASC15" MicroRNA hsa-miR-155:PITA hsa-miR-155:PITA_TOP PITA 1.96E-37 1.09E-33 6.44E-37 5.93E-36 72 304 "FMNL2,ABCD2,FAM135A,C6orf89,LCORL,MAP4K3,KSR1,CCPG1,CLCN3,CSF1R,SOCS5,BOC,RHOBTB1,DYNC1I1,NR1D2,MBNL2,KCTD3,PLEKHA1,C3orf18,FOXO3,RAB30,MIER3,IGF1,JAK2,KCNN3,SMAD1,LRP1B,MEIS1,MITF,ZC3H12B,NFIX,NOVA1,PCDH9,PDE3A,GPR85,PIK3R1,CCSER2,XRN1,STRN3,CEP41,PKIA,ELOVL2,PTPRD,SATB1,CHD9,FBXO11,SLA,BTBD3,SEPHS1,CPEB4,SMARCA4,SOX11,HECW1,NKAIN2,RGL1,SYPL1,CAMTA1,TCF4,SATB2,TRIM2,TCF12,SIRT1,TRPS1,SGK3,CELF4,ZBTB38,SMARCAD1,NAV3,KAT6A,HNRNPA3,FXR1,ST8SIA2" MicroRNA hsa-miR-196b*:mirSVR_lowEffct hsa-miR-196b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-37 1.21E-33 7.11E-37 6.54E-36 95 540 "NDRG3,ARHGAP20,GPRASP2,PHF12,VAT1L,CDK10,CASK,RNF182,RIPK1,TTLL9,BACH1,GYG2,PTBP2,SRSF11,B4GALT6,NRXN3,AKAP6,SUMF2,MAGED1,ABI3BP,CREM,CSF2RA,ARHGEF10,OSBPL3,RUBCN,KCTD8,GIT2,DGCR5,SV2B,DTNA,DNAJB6,ABCC5,AASDH,HIPK3,FRY,PHF20L1,GOLGA7,GPHN,FGFR1,FHL1,SYNCRIP,FLNC,SLC37A3,FAM49B,CSPG5,TCERG1,GLYR1,DIDO1,GRM8,AP4S1,HSF2,CELF5,LRRCC1,IDNK,DNHD1,P2RX7,SERPINI1,STRN3,PCDHB17P,PRPH,TMEM260,PTPRO,RASGRF2,REV3L,ROBO2,SNX22,TRA2B,SH3GL3,LGI3,SNAP25,MYO16,ADHFE1,KLHL7,PRRC2C,CAMTA1,DNMBP,ZEB1,DOCK9,PCDHB7,PUM2,RNF216P1,ZFPM2,SLC44A1,ARL10,TRO,LAT2,CLDND1,XRCC4,PRDM10,TUBA1A,KCNAB1,DOCK8,SMIM8,CASC15,SNX14" MicroRNA hsa-miR-1304:mirSVR_highEffct hsa-miR-1304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-37 1.38E-33 8.11E-37 7.46E-36 115 780 "KLHL32,PWWP2A,LRFN2,SLC24A4,KIAA1324,ANK2,SLC4A4,ADAM15,MPDZ,CFLAR,SYNJ2,BAIAP3,KRIT1,C1orf52,B4GALT6,RAB33A,CLTC,FAM189A2,CNGA3,ARMC8,AKAP6,LETMD1,ZFP28,CLIP3,SOCS5,CENPL,AIF1L,GIT2,EXOG,DNM1L,E2F5,ELN,TMEM35A,EPB41L2,FAM198B,PRMT5,KAT8,PPP1R1B,ZNF589,GORAB,BAIAP2,PSD2,ATP6V1H,KHDRBS3,ZNF234,GNAL,ADGRA3,PRUNE2,MCHR1,GRIN2C,HMGCL,LRRCC1,SCIN,FAM69A,LRRTM1,KCNN3,KHK,LAMP2,ZNF667-AS1,MAN2A2,MBNL1,MEIS2,MID1,ZNF680,MYO7A,ZC3H12B,NINJ2,CNOT4,NUCB2,PFKFB2,TMIE,CCSER2,SNX10,SMOX,MBOAT7,SH3KBP1,GDPD2,ELOVL2,SPDL1,PTPRB,USP47,SH3TC2,UBR7,ROBO1,MEG3,ZNF568,SATB1,LRFN5,CPEB3,ABLIM3,TET1,KDM4C,ZC3H13,DDN,NFASC,CLSTN2,TTBK2,SYT1,ZEB1,GPRIN3,HEY1,NR2E1,TMPO,C9orf85,RUNDC3B,TUBB2A,UGT8,ZFP41,LINC02210,MDH1B,NAV3,PDSS2,PHTF2,MSRB3,JPH3" MicroRNA hsa-miR-323a-3p:TargetScan hsa-miR-323a-3p TargetScan 2.57E-37 1.44E-33 8.43E-37 7.76E-36 78 362 "ADCY6,KIAA1211,OSBPL8,FAM135A,C6orf89,PHF12,INSYN2B,NRP2,FUBP1,MTMR2,CACNA1G,LDLRAD4,CABP7,KALRN,RUNX1T1,CERS5,CBFA2T2,C1orf52,MAP4K4,FHL5,NRG2,NSL1,CDC42BPB,APPL1,PUM1,DOCK4,BRINP1,ELMSAN1,JAKMIP2,KLHL3,RCAN1,HIPK3,EGR3,KCTD3,DCTN4,EIF1,ENPP6,ERBB4,SEC23B,FUT9,MPP6,GAD1,PCDH17,GHR,MSL3,MAP4K5,HMGCR,IGF1,KCNB1,KCNQ3,KITLG,MITF,MKLN1,NFIX,PCDH8,PDE4B,PDE4D,GPSM2,LRP12,EML5,RAP1GDS1,ENOX1,RFX3,CSRNP3,FNIP1,ARX,CPEB3,BTBD3,CPEB4,MBD5,KDM3A,DDN,LMO3,ANKRD28,FAM189A1,CBX5,CSMD1,JPH3" MicroRNA hsa-miR-653-5p:TargetScan hsa-miR-653-5p TargetScan 2.99E-37 1.67E-33 9.80E-37 9.02E-36 86 444 "ABR,PLEKHH1,PTCHD1,BEND6,PCDH10,AMPD2,APC,PPFIA3,CCDC74A,BACH1,CAST,DLGAP1,CDR1,MYL6B,CNR1,FAM171B,CLOCK,CS,PLCXD3,PYGO1,PABPC5,ARMCX2,ELMSAN1,DPYSL2,EBF1,EIF1,RCAN2,KATNAL1,MAD2L2,FOXO3,CELF1,FUT9,MPP6,GHR,PPARGC1A,LUZP2,PRRC2B,PRDM5,LINGO1,NCKAP1L,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,IGF1,IL6ST,INSM1,KIF2A,MEIS2,POC1B,MYO6,NCAM2,NOVA1,GPR137C,CNTN3,SCHIP1,PPP2R5E,PRKAB2,CEP41,DIRAS2,APTX,ANKHD1,EML5,PTPRG,GTDC1,ROBO2,CSRNP3,FNIP1,HSPA4L,FHOD3,ANKRD6,NMNAT2,MCF2L,CLASP1,NSD1,ITGB3BP,GPR161,ASXL3,NR2C2,LAMP5,DHX33,EVI5,PLSCR4,RTN4,MSRB3" MicroRNA hsa-miR-885-3p:mirSVR_lowEffct hsa-miR-885-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.16E-37 1.77E-33 1.04E-36 9.55E-36 115 782 "KDM5D,ADORA1,UNC5A,AP2A2,DOC2A,PKP4,KCNAB2,UPRT,SLC2A11,DPY19L3,ADAM15,ADGRB2,ARHGEF7,CAMK2A,P2RX6,CCPG1,NDST3,WHRN,ABI3BP,SMARCAL1,ZNF521,CREM,AATK,PDE4DIP,LONRF1,ARMCX2,HEPH,DMPK,DYNC1I1,CPEB2,DOCK2,TOM1,KRBA2,TSPAN5,EDN3,FAM13A,EIF4G2,KAT8,CELF1,SDCBP2,GABBR1,GABRG2,ACSS1,LRRC37A6P,TUBA8,SESN1,GLI2,GNAO1,ADGRA3,GP1BB,C1QL4,PLPP7,ATE1,DHX35,INSM1,ITGA7,L1CAM,CLEC18A,MBNL1,PPM1L,GIT1,MYO9A,PCBP3,CHAMP1,PCDH9,PRTG,GNG2,PFKFB3,PNMA3,PMP22,MAPKAP1,FSD1,PPP1R1A,PPP2R2B,PIGG,TMEM260,RIPOR1,RASGRF2,ZDHHC14,CRTAC1,SETD5,SNX22,MEG3,FAM192A,SAFB,SMPD3,SEC14L1,ARFGAP1,RCOR3,ANKRD36,LIMCH1,GLT8D1,KDM4C,ZNF423,IQSEC2,CAMTA2,ST5,ADHFE1,EXOC7,TPCN2,SYNE1,HIF3A,AP4E1,TNS1,RASD2,CDK20,TTC3,SGK3,LAT2,ZNF19,ZNF70,DNALI1,DOCK8,ST7,SNX14" MicroRNA hsa-miR-376c:PITA hsa-miR-376c:PITA_TOP PITA 4.08E-37 2.28E-33 1.34E-36 1.23E-35 71 298 "ABR,ADCY6,PCDH19,ALCAM,AMPH,MAP4K3,NCOA1,BCL7A,CACNA1G,LDLRAD4,CACNA2D1,CALB1,PTBP2,CHN1,RAB28,NRXN3,CLOCK,ERC2,KIF26A,MFAP3L,DLX1,EDN1,FRY,PAN3,ANKFY1,MEGF10,GABRG2,SPIN1,GRIA2,ATXN2L,AGFG1,INSM1,SFXN5,NCOA7,CHIC1,MEF2C,MEIS2,SAMD5,NEXMIF,NEFH,XRN1,EPB41L4B,PTPRD,TMEM255A,USP47,MSANTD2,ROBO1,RORB,CCDC112,SEMA6D,SATB1,ABLIM3,SLC8A1,CPEB4,RCOR3,LARP4,ERBIN,TTBK2,DNMBP,ADGRL3,SATB2,TIAM1,RIMBP2,TRPS1,SGK3,VLDLR,CELF4,SLC30A3,KAT6A,HNRNPA3,KLHDC1" MicroRNA hsa-miR-455-5p:mirSVR_highEffct hsa-miR-455-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.20E-37 2.35E-33 1.38E-36 1.27E-35 107 685 "NCKAP5,ACTN1,XKR4,INTS2,KLHL13,RTL9,OSBPL1A,BBOX1,FAM135A,AMPH,LCORL,ARNTL,CDK13,DPY19L3,CFLAR,DST,CACNB4,THSD7A,CAST,CLGN,SRSF11,MS4A7,RAB33A,QKI,SRP14-AS1,COL4A5,RCHY1,CREM,VAC14-AS1,DZIP3,ERC2,PUM1,DOCK4,GPRASP1,ZFYVE16,ZNF337,MYEF2,FBXL5,KIF19,USP3,DTNA,DTNB,PHF20L1,PLXNC1,ADGRV1,FGF12,FGF13,AP4B1,OGA,GAD1,B4GALNT1,C15orf41,ACSS1,GHR,LOXL3,GPD2,PRDM5,FRMD5,INSYN1,HMGCL,NKD1,IL6ST,KLHL23,KCNN2,PIK3AP1,TM6SF1,ADAM22,LAYN,NF1,GPR85,FAM218A,XRN1,PCDH18,EPDR1,MASP1,VPS13C,TMEM260,PTPN13,CRTAC1,RGS4,EXD2,GLDN,PTGR2,CPEB3,KBTBD4,TET1,SNRPN,PDZD2,SS18,ERBIN,ELOVL4,KLHL7,SYNE2,SATB2,DOCK9,GPRIN3,ITGB3BP,CDH22,FAM124A,STXBP4,PPIL6,XRCC4,ZSCAN26,SMARCAD1,HPS4,HNRNPA3,KLHDC1" MicroRNA hsa-miR-587:PITA hsa-miR-587:PITA_TOP PITA 4.48E-37 2.51E-33 1.47E-36 1.35E-35 83 415 "ASIC1,GALNT13,PTCHD1,PCDH19,C1QTNF3,FAM135A,PKP4,USP37,CADPS,MARCH3,ZBTB10,SLC4A4,CACNB4,THSD7A,CALM1,LRBA,B4GALT6,ARMC8,AHCTF1,SLC35F1,CSNK1G3,CNTNAP2,DOCK4,GAPVD1,HDAC4,DAPK1,MFAP3L,ZC3H11A,RAB39B,DMD,CPEB2,PLEKHA1,ERBB4,ETV1,AFF2,CHL1,GABRB3,TCERG1,GRIA2,ADAMTS6,MIER3,NKD1,KCND2,MBNL1,MYO5A,GPR137C,PCDH9,PDE4D,NALCN,MINDY2,CEP41,PKIA,USP47,ZFHX4,FBXW7,KCNIP1,FNIP1,TNFRSF19,SCAF8,SLC12A2,SOX11,NMNAT2,CDK19,NKAIN2,ERBIN,RGL1,CAMTA1,TRIM2,USP22,SLC44A1,THRA,NR2E1,KAT6B,TPM1,TRPS1,UBE3A,ZIC1,MICU3,SLC38A1,EVI5,URM1,MSRB3,FRMD6" MicroRNA hsa-miR-486-5p:mirSVR_highEffct hsa-miR-486-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.10E-37 2.86E-33 1.67E-36 1.54E-35 86 447 "KCNH8,NCKAP5,KLHL32,BEND6,AK2,FAM135A,SUGT1P4-STRA6LP-CCDC180,MAGEE2,DYNLL1,NRP2,CA8,CCNH,SRSF11,NRXN3,CNGA3,ARMC8,SLC4A8,LYPD1,DTNB,RASGRP1,AASS,EIF1,GPHN,FGF13,PRELID3A,CELF1,CSPG5,GABRB3,INPP5K,GCNT2,DBF4,FERMT2,CIT,FRMD3,MIER3,MYLK2,LRRC25,PIK3AP1,MARK1,MATN2,MEIS1,MXI1,ALDH1L2,PIK3R1,ZNF655,TRHDE,MAPKAP1,POLG,PPM1B,RAD51D,RBBP6,RGS4,NUDT11,NEK11,BAALC,ST6GALNAC6,ZNF331,NLGN1,BTBD3,MYH15,RCOR3,MBD5,PDZRN3,PDZD2,ST5,KANK1,PRRC2C,DNAJC9,SYPL1,WSCD1,PUM2,TEK,SIRT1,SLC44A1,ERCC6L2,R3HDM1,UGT8,PLEKHH2,MTCH1,CCDC14,REEP1,ZSCAN26,SMARCAD1,SLC38A1,MRPL47,FXR1" MicroRNA hsa-miR-20b-5p:Functional MTI Functional MTI miRTarbase 5.89E-37 3.30E-33 1.93E-36 1.77E-35 125 917 "FMNL2,ADD1,FZD9,SORCS2,ZNF578,SEMA7A,ATP1B3,LDHD,ARHGEF7,MTMR3,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,SOCS5,UBXN2A,DCAF8,DNAL1,YTHDC1,ELMSAN1,FBXL5,SACS,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,HIPK3,FEM1B,KMT5B,EIF4G2,IRAK4,CERCAM,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,TPK1,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,FUT10,CIT,FICD,HAS2,ITPKB,KCNB1,CAMK2N2,GPR155,CHIC1,SCAMP5,AFF1,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,CEP97,OXR1,ZNF532,ATAT1,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,BTBD7,CMTR2,FAM126B,SP2,SP4,STAC2,ANKRD12,CAMTA1,TCF4,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,PARD3,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-500*:mirSVR_highEffct hsa-miR-500*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.55E-37 3.67E-33 2.14E-36 1.97E-35 99 593 "RALGAPA1,NDRG2,BRAP,SUGT1P4-STRA6LP-CCDC180,APAF1,USP37,TTLL9,DDR1,KALRN,CAMK2G,PRC1,CD38,CDH2,CNN3,FAM171B,SEC31B,HAPLN1,RNF14,SEC24C,PHACTR3,DOCK4,HDAC9,ZNF337,LIN54,MATR3,PLPPR4,SACS,SGSM2,NR1D2,HIPK3,FCF1,TMEM132E,DCTN4,RASL12,F8,SCML2,PRMT5,ATP13A4,NBEA,STAU2,MSTN,DHRS4,ZNF638,PRRC2B,CIT,RNFT2,GABARAPL2,IDH3B,RBPJ,SLC35G1,MATN2,MATN3,MBD1,MBNL1,MIA2,NEK1,GLIPR1L2,PCSK5,PDCD2,PDE4D,PLCB2,POLG,PPP2R2C,PPP2R5E,PPP3CC,BDNF-AS,SH3TC2,REV3L,FIGN,UBR7,ZFHX4,EXD2,RPL15,FBXW7,ABCA11P,CLIP1,SATB1,CNKSR2,PPP4R3A,DHX30,TET1,TRERF1,HECW1,KDM4C,ZBTB43,ATP10B,NXT2,PRRC2C,DOCK9,GPRIN3,CSMD1,SMUG1,UBE2H,MGAT5B,ZNF711,MAP3K12,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-1231:mirSVR_highEffct hsa-miR-1231:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.14E-37 3.99E-33 2.33E-36 2.15E-35 101 617 "NCKAP5,ACTN1,FAHD2CP,BEND6,AMPH,UPRT,SEMA4G,ARNTL,RASL11B,KSR1,SGCE,KALRN,PTBP2,PRC1,RAB33A,NRXN3,FAM189A2,QKI,IQCK,SUMF2,CREM,TRIM69,UBXN2A,GREB1,IP6K1,AIF1L,DNAH9,DMTF1,DPP6,AASDH,EGFR,TMEM35A,STARD3NL,FGF14,FGFR1,FOXF2,FLT1,TRAF3IP2,ZNF274,DISC1,SULT1C4,GHR,RAB30,WDFY3-AS2,CCDC184,STON1,AP4S1,PSIP1,ARHGAP36,VSIG4,SYNPO,SMAP1,SLC35G1,MBP,MEIS2,LYRM9,NEFM,NOVA1,SLC11A2,MTRF1L,MBOAT7,GRAMD1C,SAMD9,GDPD2,QRICH1,CNTLN,TMEM260,SUSD4,RASGRF2,NUDT11,RNASEL,KIAA0895L,GLDN,ATAT1,DGLUCY,SEMA6D,SCP2,PPM1E,FRMPD1,FERMT1,ZNF430,SLC11A1,SYNE2,DNAJC9,C12orf76,SMG6,SATB2,ZEB1,TIAM1,MTMR14,TMPO,TRO,DCBLD1,WIPF1,CELF4,REEP1,FIP1L1,SMIM8,MSRB3,GAN,FAM198A" MicroRNA hsa-miR-214:PITA hsa-miR-214:PITA_TOP PITA 7.29E-37 4.08E-33 2.38E-36 2.19E-35 73 319 "KCNH8,UNC5A,INTS2,SEMA6A,MARK4,CHRD,CACNA1I,LURAP1,FOXN3,NRXN3,QKI,PICK1,COL4A5,TBPL1,MYRIP,IGDCC3,SEC24C,SOCS5,RIMS4,PUM1,RUBCN,JAKMIP2,MYEF2,DNAJB6,PHC2,YAF2,EIF4G1,TAOK3,FHL1,AGAP2,AFF2,FAM49B,SESN1,AHDC1,PCLO,ZIC5,MAP2,CHIC1,MITF,MOV10,GPR85,RETREG2,KANSL1,TMEM260,PID1,OXR1,DUSP15,SETD5,SPIN3,SALL1,SEMA6D,SCP2,CPEB3,MYO18A,CNKSR2,ANKRD6,ABLIM3,SLC8A1,CPEB4,SOX11,PEG10,MMS19,CAMTA1,DMXL2,SZT2,DOCK9,TRPS1,FAM155A,UBE2H,KLC2,ZIC1,PPP1R3F,HNRNPA3" MicroRNA hsa-miR-519d-3p:Functional MTI Functional MTI miRTarbase 7.58E-37 4.24E-33 2.48E-36 2.28E-35 124 906 "FMNL2,ADD1,FZD9,SORCS2,ZNF578,SEMA7A,ATP1B3,LDHD,ARHGEF7,MTMR3,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,SOCS5,UBXN2A,DCAF8,DNAL1,YTHDC1,ELMSAN1,FBXL5,SACS,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,KMT5B,EIF4G2,IRAK4,CERCAM,DNAJC27,TLR7,KATNAL1,EZH1,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,TPK1,GABBR1,TRAF3IP2,ERAP1,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,FUT10,CIT,FICD,HAS2,ITPKB,KCNB1,CAMK2N2,GPR155,CHIC1,SCAMP5,AFF1,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PPARA,PRKACB,PRKCB,VPS13C,CEP97,OXR1,ZNF532,ATAT1,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,BTBD7,CMTR2,FAM126B,SP2,SP4,STAC2,ANKRD12,CAMTA1,TCF4,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,PARD3,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-593*:mirSVR_highEffct hsa-miR-593*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.43E-37 4.72E-33 2.75E-36 2.53E-35 102 630 "AS3MT,METAP1D,FMNL2,ADCY5,ADCY6,GALNT13,AXIN2,PLEKHH1,PWWP2A,KCTD16,AMPD3,OGT,LRCH2,UPRT,BCAS1,LGR5,ADGRB2,BTK,CA8,CALB2,CERS5,NUMBL,CLCN3,ANKRD44,SOCS5,UBXN2A,IST1,SPOCK2,PABPC5,GIT2,HEPH,FBXL5,SPOCK3,DTNA,SNX29,EDNRA,FCF1,PHF20L1,EGFR,FDFT1,AGAP3,SEMA4D,UFM1,TPK1,CAMKK2,AP4B1,GDF9,RAB30,LOXL3,GNAO1,AP4S1,SMAP1,TJAP1,KCNN3,PACRG,MARK1,MMP16,ZNF92,NPTX2,NUCB2,LOC100128398,PDE4B,ZDHHC8,NALCN,PIK3C2A,ZNF655,PLCL1,PLEC,PMP22,EPB41L4B,GRAMD1C,SAMD9,PTPRB,ZSCAN2,GTDC1,DCUN1D2,ROBO2,SEMA6D,SUPT20H,MYO18A,ELMO2,TET1,RCOR3,DOP1A,ATP10B,CLASP2,STAU1,ADHFE1,SYNE2,CAMTA1,SYNE1,FAM200B,ZFPM2,SLC44A1,CSMD1,TRPS1,VLDLR,WIPF1,MAP3K12,EMSY,MFF,IFT88" MicroRNA hsa-miR-1207-5p:mirSVR_highEffct hsa-miR-1207-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.44E-37 4.72E-33 2.75E-36 2.53E-35 115 790 "ASPHD1,ADD2,ZNF608,KIAA1324,ALCAM,BEGAIN,AMPD2,APC,CHRD,ADAM15,RGS11,CACNA2D1,SLC25A14,NFS1,PLEKHB1,AKAP5,ZFP28,SEC31B,SNCAIP,ARHGEF10,SUSD5,RIMS2,DCAF4,BOC,GIT2,RHOBTB1,HS3ST2,CPEB2,SLC25A18,DTNB,KLHL5,CELSR3,PHF20L1,SUGP2,APH1A,C3orf18,PPP1R1B,IP6K2,AGAP3,FLT1,CELF1,ABLIM2,MEGF10,B4GALNT1,ERAP1,C15orf41,CYP46A1,MSL3,CBX1,STMN2,SPACA9,COQ10A,SLC2A6,SHISA6,NKD1,DISP2,IL6ST,INSM1,PAXBP1,NCOA7,LSS,ZFYVE27,MARK1,KCTD6,MPP2,RTL5,NME4,NOVA1,NTRK3,PCSK5,GPR173,CCSER2,NLE1,MBOAT7,EPB41L4B,SH3KBP1,VSTM2L,CEP41,MASP1,BCAS3,ZNF844,TRIM68,GTDC1,SLC25A36,CARF,FBXW7,CASC3,CCDC92,SYBU,DHX30,FAM214B,ARHGEF40,SLC9A5,KDM4B,ZC4H2,CEP68,ADHFE1,ZC3H4,MLST8,CLASP1,OBSL1,FRYL,RNF216P1,TPM1,NPL,TPM2,RGMB,PLPPR2,WIPF1,XRCC4,TMEM198,ADAMTS9,NAV3,SLC17A7,GAN" MicroRNA hsa-miR-508-5p:mirSVR_highEffct hsa-miR-508-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-36 6.15E-33 3.58E-36 3.30E-35 106 680 "KCNH8,KLHL32,CCDC85A,CC2D2A,FGD2,SUGT1P4-STRA6LP-CCDC180,TNRC6C,RGS20,ATP2A2,SYNJ1,CAST,LDB2,RAB33A,CNRIP1,SLC35F1,FAM171B,AKAP12,PDE4DIP,GREB1,CYBB,ZFYVE16,C2CD2L,TMCC2,WDR20,DMD,DTNB,FCF1,KLHL5,EGR3,F8,CLVS1,CEP78,GORAB,ATP13A4,ANKFY1,HVCN1,CELF1,IQGAP2,TUBA8,ARFIP1,FREM1,RAB30,TNRC6A,GRIA2,PLCD4,MAP4K5,HNF4G,SHISA6,NKD1,SCIN,INSM1,C2CD4C,LAMP2,COL28A1,BLOC1S2,NEFH,NF1,PCSK1,PDE4B,ABCB1,PSAT1,GRAMD1C,PTK2,TMEM260,RBBP6,RIC8B,EXD2,CARF,ARMH4,FBXW7,BAALC,LRFN5,FUZ,FBXO11,SLA,KANSL3,NAPB,KIF13A,SNRPN,UHRF1BP1L,SEPT3,ANKRD28,TBL1X,KLHL4,SATB2,GPRIN3,FRYL,FAM200B,DICER1,ARL10,MTMR14,BHLHB9,ERCC6L2,TPM1,TRIO,TRO,TSN,HSPBP1,PLEKHH2,CCDC14,CFAP298,TRIM9,ZNF45,HPS4,CASC15,TIGD6" MicroRNA hsa-miR-571:mirSVR_highEffct hsa-miR-571:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-36 6.79E-33 3.96E-36 3.64E-35 97 574 "CLK4,ADD2,BEND6,RTL9,MARCH4,APOC2,SLC4A4,ATP2A2,SEC11C,NRP2,PTBP2,CAPN3,CERS5,TIGD7,PPT2,QKI,ABCG1,PDE4DIP,PUM1,GPRASP1,RIPOR2,SPATA2,DDX46,DMTF1,EDN3,RABEPK,ERBB2,IGSF6,FCGR1A,FCGR3A,ZSCAN30,SPSB4,SYNCRIP,DCTN2,KHDRBS3,FYB1,CHL1,LINGO1,RASSF8,IL6R,NME9,CREG2,KTN1,NCOA7,ZNF667-AS1,MAT2A,PPM1L,NRBP2,NLGN3,EPB41L4B,PPP3CC,PRKACB,HYDIN,LAMA1,OXR1,RBBP6,GTDC1,RNASEL,ZFHX4,ROBO2,RORB,EPHA10,BAALC,GLDN,ATAT1,KCNIP1,CSRNP3,ASAP3,MYO18A,ZNF415,HECW1,LMO3,ZC4H2,LARP4,ADHFE1,KLHL7,NECAB1,MTCL1,DNMBP,FAM208A,TCEA1,SATB2,RPGRIP1L,PCDHB7,SLC44A1,TLR4,CLHC1,OSBP2,ZNF781,RICTOR,XPO1,TRIM9,CELF4,ADAMTS9,SLC17A7,RTN4,FAM181A" MicroRNA hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA_TOP PITA 1.36E-36 7.61E-33 4.43E-36 4.08E-35 70 294 "ALCAM,FAM135A,CACNB4,CALM1,PTBP2,DCLK1,SOCS6,LHX2,AKAP6,CSNK1G3,PHACTR3,MATR3,SGSM2,KMT5B,EGR3,RGS17,RCAN2,SEC24B,IP6K2,GATM,GHR,PPARGC1A,SPIN1,TNRC6A,STON1,BACH2,IGF1,ZIC5,IPO5,MBNL1,NEXMIF,ZC3H12B,NFIX,PDE3A,GPR85,OLA1,ANKRD16,SCHIP1,KANSL1,CEP41,RELN,SH3TC2,OXR1,RDX,ZFHX4,RORB,SALL1,SEPHS1,SLC12A2,NAPB,CPEB4,RCOR3,FAM126B,LMO3,SS18,NECAB1,SYT1,TCF4,TRIM2,RPGRIP1L,PUM2,SIRT1,SLC44A1,RIMBP2,TPM1,CLDND1,ZNF711,RNF103,TIGD6,FRMD6" MicroRNA hsa-miR-640:mirSVR_highEffct hsa-miR-640:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-36 7.70E-33 4.48E-36 4.12E-35 112 756 "INTS2,GPRASP2,TNRC6C,LGR5,ARRB1,PLA2G4C,MARCH3,ADGRB3,DST,CA8,EPS15L1,CLTC,QKI,IGLON5,CNR1,ANKRD35,MAGED1,ABI3BP,SEC24C,CYBB,DOCK4,ZFYVE16,PABPC5,ZBTB24,TIAM2,ZC3H11A,GRIN3A,DTNA,E2F5,AASDH,EIF5,RASGRP2,ENPP6,EXTL2,DLC1,GORAB,ANKFY1,PSD2,COQ5,OGA,GALNT15,GALC,DISC1,SULT1C4,GLI2,STMN2,RASSF8,KCND1,KCNH2,LAMP2,HECTD2,LSS,PIK3AP1,MBNL1,POC1B,MITF,COL28A1,ADAM22,MXI1,NF1,NOVA1,CHAMP1,ABCB1,PIK3C2A,PSAT1,PPP2R2C,PIGG,BDNF-AS,TMEM260,PTPRD,PCMTD2,NEK11,PTGR2,ATAT1,FBXO11,WDR37,BTBD3,SLC9A5,ATF7IP,SMARCA4,TMCC1,DOP1A,KDM4C,NFASC,NKAIN2,CEP68,KANK1,TBCEL,WSCD1,TCF4,PUM2,FAM200B,DICER1,BHLHB9,BEX4,TPM1,METTL3,AMACR,TSN,ANKRD20A2,UGT8,VLDLR,PCDH20,ZNF23,UPF3A,EMSY,CADM2,NAV3,URM1,FZD3,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-943:mirSVR_highEffct hsa-miR-943:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.66E-36 9.29E-33 5.40E-36 4.97E-35 109 720 "ACADM,CCDC85A,BRAP,TXNDC16,CASK,TMEFF1,NUMB,KIF1A,AZGP1,ADGRB3,JAZF1,LURAP1,CARS,SPAG9,P2RX6,SCARB1,DGKI,MAGI1,CFL2,IQCK,ABI3BP,RTTN,SOCS5,ERC2,PUM1,TMEM170A,PABPC5,ARMCX2,PLPPR4,CDON,SLC25A18,DTNA,ANKRD46,PHF20L1,MRO,CEP85L,FCGRT,HPCAL4,ZMAT1,GABRB3,ZNF559,DISC1,MSTN,NFU1,MALT1,CRCP,RNPS1,ZNF638,MAP7D2,PCLO,SPACA9,ELOVL5,NEGR1,SMAP1,HECTD2,MAP2,LRP1B,PPM1L,MKLN1,NF1,NOVA1,SLC11A2,NRCAM,NUCB2,LOC100128398,PDE3A,GNG2,FAM218A,XRN1,MTRF1L,PRIMPOL,TRHDE,EPDR1,GRAMD1C,TMEM260,PID1,NWD1,ENOX1,ZNF493,RDX,ZMAT4,RPL15,FBXW7,ZNF354C,ARX,CPEB3,CHD9,SEC31A,BTBD7,GKAP1,DOK5,NEK4,RGL1,NSFL1C,MTCL1,FAM208A,CUX2,TCF12,CDH22,NR2E1,TMPO,SGK3,XRCC4,FSTL5,ZXDA,PRTFDC1,EPM2A,CASC15,KLHDC1" MicroRNA hsa-miR-802:TargetScan hsa-miR-802 TargetScan 1.75E-36 9.80E-33 5.69E-36 5.24E-35 69 286 "HECW2,KCTD16,APBB2,APC,ATP1B3,DST,CACNA1I,C1orf52,DCLK1,FOXN3,CLCN3,QKI,ARMC8,RTTN,PNPLA8,LIN54,MATR3,JAKMIP2,DOCK2,DPYSL2,RCAN1,DNM1L,EDIL3,MBNL2,PAN3,DCTN4,MEX3B,FAM49B,NEURL4,MEGF11,RAPGEF6,GLUL,GPR37,MIER3,NEGR1,AGFG1,KCNB1,KLHL23,IPO5,MBNL1,MEF2C,MSI1,MYO9A,PCSK5,PDE4D,PLCL1,PPP3CA,BCAS3,PTCH1,PTPRG,GTDC1,PBRM1,MCMBP,CASC3,CPEB3,BTBD7,CPEB4,MBD5,FAIM2,NMNAT2,ERC1,CDK19,EXOC7,NSD1,ITGB3BP,EVI5,HNRNPA3,JMJD1C,NETO2" MicroRNA hsa-miR-764:mirSVR_highEffct hsa-miR-764:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.90E-36 1.06E-32 6.16E-36 5.67E-35 95 554 "KLHL13,AGT,KIAA1324,CDK13,NCOA1,N4BP2L1,NRP2,KSR1,DST,ARHGEF7,IL33,KALRN,CAST,CCNH,SLC16A4,CLTC,AKAP6,COX4I1,TRIM69,SNCAIP,TCAF1,DTNA,PHF20L1,ELN,MFSD10,COQ7,RCAN2,ANKMY1,SCML2,FGFR1,UBE2E3,FAM49B,USP21,CELF1,FYN,MEGF11,GATM,GCNT2,SRCAP,LOXL3,PRDM5,CLASRP,METTL21A,KCNN1,LIMS1,MARK1,NINJ2,NOVA1,DNHD1,TBC1D25,IGSF11,PCDH8,SLC10A4,FAM216A,PRIMPOL,MAPKAP1,DRAM2,PPM1B,RASGEF1B,MAPK10,ANKHD1,PEX2,ENOX1,PRIMA1,SLC25A36,RNASEL,RORB,BAALC,KIAA0895L,TCP11L1,ATAT1,CLIP1,NCBP3,HKDC1,ABLIM3,DHX30,ELMO2,IFT122,FAIM2,ZNF302,NUDT10,SYT1,ZEB1,SYNE1,ZFPM2,PDSS1,UBE2H,TOM1L2,P2RY12,TMEM237,STOX2,NAV3,DNAH10,JMJD1C,RNF146" MicroRNA hsa-miR-1226*:mirSVR_highEffct hsa-miR-1226*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-36 1.37E-32 7.92E-36 7.29E-35 109 723 "CLK4,DPY19L2P4,ADGRF5,AMPH,OGT,SUGT1P4-STRA6LP-CCDC180,SHROOM2,PPP4R4,CCAR2,EIF4G3,CARMIL3,KSR1,BTK,RAB29,DDR1,CACNA2D1,NFS1,LRBA,CDO1,QKI,FHL5,SMARCAL1,SEC31B,GDA,CLIP3,CS,SNCAIP,SLITRK5,ZNF337,ARMCX4,HEPH,GRIN3A,DNM1,ACOT8,DTNA,ABCC5,ANKRD46,CNNM1,CERCAM,C8orf37,EMX2,CEP78,ZSCAN30,C2orf88,FAM49B,CGREF1,AP4B1,FYN,GABRG2,ZNF274,NEU3,TUBA8,SULT1C4,ADGRA3,TDRKH,PCLO,GRIA2,KAT7,BVES,ARHGAP36,VSIG4,MSL1,FAM95B1,SLC35G1,KCNB1,KCNH2,KIF5A,NCAM2,NDP,DUSP26,SEMA5B,EXOSC10,SCHIP1,GDPD2,ZSCAN32,PTPRB,MARCH1,OXR1,ZNF532,ABCA11P,ATAT1,TRAPPC13,FAM192A,TNFRSF19,FAM81A,FAM214B,SMARCC2,RCOR3,MYO16,KDM4C,ADHFE1,ADAMTS17,TRIM2,ICAM5,TPM1,TPM2,ELP5,PDSS1,AMACR,RPL7L1,UBE3A,WNT7A,PCDH20,ZXDA,MFF,DNALI1,RGS7BP,UBE3B,ADAMTS10" MicroRNA "ATATGCA,MIR-448:MSigDB" "ATATGCA,MIR-448:MSigDB" MSigDB 2.71E-36 1.51E-32 8.78E-36 8.08E-35 59 203 "ADD1,UNC5A,HECW2,DOC2A,ANK2,APBB2,ARNTL,PCDHGB4,RNF182,USP6,ARMC8,SOCS5,DAPK1,BRINP1,CPEB2,KLHL5,MBNL2,GPHN,ETV1,AFF2,NBEA,GABRB3,BACH2,KCNB1,HECTD2,MEF2C,MYH3,PCDHGC3,PCDH8,PCDH9,KCTD15,ING3,SH3KBP1,PRKAB2,CEP97,ZFHX4,RORB,NLGN1,SOX11,CDK19,SS18,SYN2,FBXW11,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,DOCK9,SIRT1,VLDLR,RICTOR,GAN" MicroRNA hsa-miR-27b*:mirSVR_highEffct hsa-miR-27b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.39E-36 1.89E-32 1.10E-35 1.01E-34 101 628 "FMNL2,CCDC85A,DPY19L2P4,INTS2,HECW2,TAOK1,OGT,ANK2,PKP4,SHROOM2,RNF182,ZNF501,SRSF11,CNR1,CNTFR,AKAP7,AKAP5,TBPL1,PREPL,RBM39,OSBPL3,APPL1,PHF14,CDON,ACOT8,DNM1L,OPTN,YAF2,PHF20L1,EIF4G1,F8,ST3GAL6,BAIAP2,EFCAB2,POMT1,TPK1,STAU2,SULT1C4,GLUL,GPD2,FAM19A2,BVES,ZHX1,CELF5,LRRCC1,LIMS1,SRSF12,NELL2,NF1,NFE2L2,NRCAM,PDE3A,SLC25A23,LRP12,TATDN3,RASGEF1B,MAPK10,PRPSAP2,GDPD1,SAMD9,PTK2,TMEM260,PTPRG,SH3TC2,RGS4,ZNF532,TMLHE,ROBO2,ADAL,ZNF568,CSRNP3,BTBD3,SIRT2,SLC12A2,INAVA,LIMCH1,USP33,SPTB,MPRIP,ZSCAN29,DIP2A,KANK1,PLCB1,ANKRD28,PCDHB7,HIF3A,ITGB3BP,TIAM1,NR2E1,SYNPO2,TRPS1,UBTF,MTCH1,VSNL1,ZNF781,CLDND1,ZNF28,ZNF189,WNK3,NETO2,SENP7" MicroRNA hsa-miR-103:PITA hsa-miR-103:PITA_TOP PITA 3.41E-36 1.91E-32 1.10E-35 1.02E-34 80 395 "ASIC1,GALNT13,AXIN2,SEMA6A,OGT,MARCH3,ZBTB10,NRP2,CACNA2D1,THSD7A,RUNX1T1,DCLK1,CLCN3,CLOCK,ERC2,PPP6R2,USP6NL,LONRF1,YTHDC1,JAKMIP2,SLC12A6,TSPAN5,SEMA3D,PHF20L1,EIF5,PLEKHA1,CORO2B,OLFM1,GABRG2,PCDH17,SPIN1,FERMT2,TMEM121B,ZHX1,BACH2,HLF,AGFG1,SLC35G1,KIF5A,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,NEXMIF,ZC3H12B,NF1,NOVA1,PIK3R1,MINDY2,LRRN3,CNNM2,SNRK,TMEM260,PID1,PRRT2,FBXW7,CLIP1,SALL1,SCN8A,PUF60,KIF21A,PPM1E,CPEB3,NLGN1,FAM81A,ZHX3,PLCB1,SYN2,ADGRL3,SATB2,RPGRIP1L,FRYL,DICER1,ZFPM2,TPM1,BCL2L13,ZIC1,ZNF711,ADAMTSL3" MicroRNA hsa-miR-107:PITA hsa-miR-107:PITA_TOP PITA 3.41E-36 1.91E-32 1.10E-35 1.02E-34 80 395 "ASIC1,GALNT13,AXIN2,SEMA6A,OGT,MARCH3,ZBTB10,NRP2,CACNA2D1,THSD7A,RUNX1T1,DCLK1,CLCN3,CLOCK,ERC2,PPP6R2,USP6NL,LONRF1,YTHDC1,JAKMIP2,SLC12A6,TSPAN5,SEMA3D,PHF20L1,EIF5,PLEKHA1,CORO2B,OLFM1,GABRG2,PCDH17,SPIN1,FERMT2,TMEM121B,ZHX1,BACH2,HLF,AGFG1,SLC35G1,KIF5A,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,NEXMIF,ZC3H12B,NF1,NOVA1,PIK3R1,MINDY2,LRRN3,CNNM2,SNRK,TMEM260,PID1,PRRT2,FBXW7,CLIP1,SALL1,SCN8A,PUF60,KIF21A,PPM1E,CPEB3,NLGN1,FAM81A,ZHX3,PLCB1,SYN2,ADGRL3,SATB2,RPGRIP1L,FRYL,DICER1,ZFPM2,TPM1,BCL2L13,ZIC1,ZNF711,ADAMTSL3" MicroRNA hsa-miR-4322:mirSVR_highEffct hsa-miR-4322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.30E-36 2.41E-32 1.39E-35 1.28E-34 87 470 "CLK4,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,VAT1L,AQP6,DYNLL1,LDHD,RUNX1T1,CLDN10,L3MBTL4,COPB2,RAB33A,CNR1,NCOR1,SNCAIP,CSF1R,PDE4DIP,DOCK4,HDAC4,BRINP1,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,PSD2,SLC37A3,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,PADI2,ZNF546,GPR62,KCNJ16,KCNN3,PAXBP1,MEIS2,LAYN,NME4,PDE3A,SAMD9,WBP1L,CNTLN,RGS3,RGS4,CSRNP3,ATF7IP,TET1,ZSWIM8,KDM4C,LMO3,VPS13A,ARC,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,RGS7BP,FAM13C,RNF146,SPATA13" MicroRNA hsa-miR-4326:mirSVR_highEffct hsa-miR-4326:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.46E-36 2.49E-32 1.44E-35 1.33E-34 103 654 "WDR35,C1QTNF3,ALCAM,PKP4,MPDZ,RGS9,ST3GAL5,CAMK2G,RUNX1T1,MAGI1,CDO1,FAM149A,CNRIP1,C2CD2,CREM,VAC14-AS1,ERC2,GREB1,HDAC9,GAPVD1,HDAC4,ALKBH8,RAB39B,DNAJB6,ABCC5,EDN1,FAM13A,MBNL2,ERBB2,DENND4A,CDKL3,ABCA8,TBC1D16,CHST15,FHL1,POLK,SYNCRIP,NBEA,STAMBP,MSANTD4,MEGF11,MEGF10,GABBR1,ALDH1L1,NFU1,ADAM28,COPS8,WDFY3-AS2,GRIA2,AP4S1,PADI2,ELOVL5,IDH3A,ITGA7,KCNB1,MAN2A2,ZFYVE27,MBD1,SCAMP5,RTL5,NTRK2,OGG1,PRTG,PDE4D,LRP12,EPB41L4B,CEP41,MAPK9,DCHS2,STK32A,SLC25A48,RASGRF2,REV3L,RNASEL,ROBO1,RPL15,ABCA11P,ATXN2,HKDC1,AMBRA1,DZIP1,SLC2A5,ZNF430,CDK5RAP3,IFT122,SP4,CLSTN2,SSTR2,NKAIN2,SIK3,TTC3,CLHC1,FAM155A,CCDC14,ZNF708,ZNF138,EPM2A,DOCK8,UBE3B,HNRNPA3,CASC15,TRAM2-AS1,DPF3" MicroRNA hsa-miR-190b:TargetScan hsa-miR-190b TargetScan 4.98E-36 2.79E-32 1.61E-35 1.48E-34 54 167 "HECW2,OSBPL6,PARG,LDLRAD4,CACNB4,HAP1,RUNX1T1,CDH2,DCLK1,NRXN3,CLCN3,CNR1,CLOCK,MYEF2,MFAP3L,DMD,RCAN2,GPHN,FGF14,MEX3B,NBEA,MPP6,C15orf41,CPLX2,PCDH17,HAS2,BACH2,NEGR1,AGFG1,IGF1,KCNB1,KIF2A,LRP1B,MEF2C,MYO5A,MYO9A,NOVA2,P2RY1,PAX6,SDK2,DIRAS2,PTCH1,MARCH1,ROBO2,HSPA4L,FNDC3A,NLGN1,CXXC4,MBD5,NFASC,DICER1,CSMD1,NAV3,GAN" MicroRNA hsa-miR-190a-5p:TargetScan hsa-miR-190a-5p TargetScan 4.98E-36 2.79E-32 1.61E-35 1.48E-34 54 167 "HECW2,OSBPL6,PARG,LDLRAD4,CACNB4,HAP1,RUNX1T1,CDH2,DCLK1,NRXN3,CLCN3,CNR1,CLOCK,MYEF2,MFAP3L,DMD,RCAN2,GPHN,FGF14,MEX3B,NBEA,MPP6,C15orf41,CPLX2,PCDH17,HAS2,BACH2,NEGR1,AGFG1,IGF1,KCNB1,KIF2A,LRP1B,MEF2C,MYO5A,MYO9A,NOVA2,P2RY1,PAX6,SDK2,DIRAS2,PTCH1,MARCH1,ROBO2,HSPA4L,FNDC3A,NLGN1,CXXC4,MBD5,NFASC,DICER1,CSMD1,NAV3,GAN" MicroRNA "GTATTAT,MIR-369-3P:MSigDB" "GTATTAT,MIR-369-3P:MSigDB" MSigDB 6.04E-36 3.38E-32 1.95E-35 1.79E-34 57 190 "AP2A1,PCDH19,FAM135A,BCAS1,CASK,CDH2,NOG,NUMBL,CFL2,QKI,KCTD8,GIT2,KLHL3,PLPPR4,WDR20,DMD,YAF2,MBNL2,EYA1,CHST15,MEX3B,AFF2,FYN,GABRB3,GFRA2,ADAMTS6,MAP2,MBNL1,LRP1B,MEIS1,NPTX1,PAX6,PDE4B,PDE4D,GPR85,PPP2R2C,CEP41,PKIA,OXR1,ZFHX4,ZNF423,CDK19,FBXW11,ATMIN,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ZFPM2,TRPS1,VSNL1,ST8SIA2" MicroRNA "TTTGTAG,MIR-520D:MSigDB" "TTTGTAG,MIR-520D:MSigDB" MSigDB 6.44E-36 3.61E-32 2.08E-35 1.91E-34 71 310 "ADD1,PCDH19,HFM1,UNC79,SEMA4G,IGDCC4,ATP2A2,JAZF1,LRBA,CDH2,DCLK1,FOXN3,NRXN3,FAM19A5,QKI,SLC35F1,CDC42BPB,CRHBP,SOCS5,CNTNAP2,PUM1,HDAC4,DAPK1,CPEB2,CASP8AP2,GOLT1B,MBNL2,EGR3,EIF4G2,UBE2E3,MEX3B,NBEA,GAD1,PPARGC1A,GNAO1,IGF1,STXBP5,MEF2C,HNRNPM,NPTX1,PDE4D,MAPKAP1,PPP3CA,DIRAS2,CNTLN,PTN,USP47,RDX,RFX3,UBR7,ZFHX4,ATXN2,PPM1E,BTBD3,CPEB4,SNAP25,PDZRN3,USP33,SOX11,SP4,SULF2,SYT1,TAL1,SIRT1,TMPO,TRPS1,UBE3A,TBC1D15,RICTOR,NAV3,JMJD1C" MicroRNA hsa-miR-149-3p:Functional MTI Functional MTI miRTarbase 7.37E-36 4.12E-32 2.38E-35 2.19E-34 117 834 "XKR4,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,HAP1,CAMK2A,ISPD,CBS,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,RASA4,PLEKHA1,MRNIP,IGSF6,FGFR1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,AGBL5,ZNF491,SOWAHA,IGF1,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,MSI1,NBL1,NFIX,NOVA2,SLC11A2,TBC1D25,OGG1,ZNF713,GPR173,PFKFB3,CCSER2,RETREG2,PPP2R2B,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,CEP97,SH3TC2,IQSEC3,PRRT2,MORC4,PGBD4,EMID1,HES6,MYO18A,PEX26,PKNOX2,ZKSCAN3,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,ERCC6L2,SSBP2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,PARP11,TMEM63C" MicroRNA hsa-miR-149:mirSVR_highEffct hsa-miR-149:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.46E-36 4.17E-32 2.40E-35 2.21E-34 111 757 "ACADM,ADD1,ADD2,ADORA2A,PCDH19,SRPX,FAM135A,SEMA4G,SLC4A4,SLC2A11,NRP2,GPR146,DDR1,NFS1,CDH2,SOCS6,ASIC3,RAB33A,DGCR9,TOGARAM2,HINFP,NCOR1,SNCAIP,SEC24C,LONRF1,ARMCX4,MYEF2,KLHL3,EXOG,HS3ST2,USP3,DNM1L,EDNRA,FCF1,IRAK4,TNK2,VPS13B,DENND4A,CLVS1,NSRP1,FCGR3A,OLFM1,FLT1,SPECC1,ZNF44,TRAF3IP2,FAM120B,IGSF5,ADAM28,GGT7,STARD3,CBX1,GRIN2C,NCKAP1L,SMAP1,ZNF181,KHK,KIF2A,ZFYVE27,MAT2A,SRSF12,NCAM2,NF1,SLC11A2,NTRK2,NUCB2,NLE1,PLIN1,PCDHB17P,PTPRO,RAD51D,MORC4,ZNF532,ROBO1,RPL15,ATP8B4,KCNIP1,DGLUCY,CASC3,SH3GL3,SHMT2,CNKSR2,ARHGEF40,NAPB,ELMO2,ZNF667,TSNAXIP1,CLSTN2,ZNF302,ZC4H2,TTBK2,EXOC7,ALG1,TCF12,BHLHB9,TPM1,CDK20,ELP5,TSN,TSC1,PLEKHH2,CCDC14,WIPF1,ZNF540,MKRN3,INTS3,PRDM8,PRDM10,CIAPIN1,AMN1,JMJD1C" MicroRNA hsa-miR-184:mirSVR_lowEffct hsa-miR-184:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.50E-36 4.20E-32 2.42E-35 2.23E-34 84 441 "ADD1,MTUS1,AK2,HFM1,AMPD2,LRCH2,PKP4,ARHGDIA,DYNLL1,ADGRB2,KSR1,ARHGEF7,ARHGEF2,CDC25B,DCLK1,PLEKHB1,TPP1,IGLON5,NCOR2,CSF1,KIAA0040,ARHGAP32,RASSF2,PITPNC1,ZBTB24,POM121,DLX1,EDIL3,CNNM1,TMTC1,EIF4G1,PLEKHA1,TNK2,EZH1,F5,FGFR1,AGAP2,EVL,ZBED3,CHL1,MSL3,POLL,LOXL3,GNAO1,GPD2,LINGO1,SLC2A6,ATXN2L,SHISA6,MAP6,SCAMP5,PTOV1,FXYD7,ALDH1L2,PRKCB,ZNF493,DPF2,UBR7,LGI2,BAALC,FAM192A,SAFB,KIF21A,SLC6A8,LIMCH1,TRERF1,SPTAN1,DDN,STXBP1,MTCL1,CAMTA1,EXOC7,SATB2,TPCN2,CYB561A3,DICER1-AS1,THRA,TNS1,TPM2,KLC2,SPHK2,GDPD5,FAM47E,NLRP3" MicroRNA hsa-miR-3116:mirSVR_highEffct hsa-miR-3116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-36 4.83E-32 2.78E-35 2.56E-34 107 708 "EMILIN3,MTUS1,C1QTNF3,PHF12,APC,ZNF582,SLC2A11,KALRN,CCK,NOG,MS4A7,PPT2,C4orf33,SRP14-AS1,ARMC8,LETMD1,AHCTF1,CLIP3,CS,RGS6,SEC24C,VCAN,FAM169A,CTH,RASSF2,DAPK1,PITPNC1,SV2B,DMTF1,ECM2,SUGP2,KMT5B,GOLGA7,EPHB1,RABEPK,ERBB2,TUBB3,GORAB,POLR1B,FGF11,FGF13,FGFR1,UFM1,MSANTD4,MPP6,SRCAP,WASHC2A,RUNDC3A,ZNF276,TOX3,ADGRA3,GPD2,GRIN2C,VSIG4,CPT1C,IRF8,FAM95B1,NKD1,INSM1,NME9,KCND1,CYP27C1,PPM1L,MYO5A,NCAM2,NF1,DNHD1,NRCAM,ZNF713,PFKFB2,ZNF655,SNX10,MAPKAP1,ING3,PIGG,PTPRB,NWD1,ZNF493,RASGRF2,RGS4,KIF7,CLIP1,SCP2,HES6,KIF27,ZFP30,KIF21A,SMARCD3,SNRPN,SP4,GLT8D1,HECW1,RBM26,ADHFE1,CAMTA1,CUX2,SYNE1,USP32P1,FRYL,CYB561A3,TIAM1,MTMR14,TSC1,VSNL1,FSTL5,FBXO36,CASC15" MicroRNA hsa-miR-24:mirSVR_highEffct hsa-miR-24:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.76E-36 4.90E-32 2.82E-35 2.60E-34 103 659 "ACADM,FMNL2,TAOK1,PCDH10,ZNF687,OGT,PHF12,SUGT1P4-STRA6LP-CCDC180,SYNJ2,THSD7A,CAMK2B,VXN,RHBDL1,SPAG9,USP2,MAGI1,CHN2,NDST3,IGLON5,ARMC8,CPS1,GDA,ABCG1,SNCAIP,RIMS2,LONRF1,MATR3,KLHL3,PLPPR4,FAM78B,ANKRD46,KLHL5,PHF20L1,TENM1,STARD3NL,PAN3,CLVS1,SCML2,DLC1,STRADA,FGF11,FHL1,STAMBP,SESN1,GGT7,CNTRL,INPP5B,ITPKB,KIF5A,SFXN5,NCOA7,SMAD9,MATN3,MEIS2,MT1M,MXI1,HNRNPM,NEFM,NELL2,DNHD1,NUCB2,EXOSC10,C19orf57,PPP2R5E,WDR25,PIGG,PTPRD,PTPRE,OXR1,HKR1,GTDC1,CARF,YY1AP1,NEK11,ADAL,LRRK2,SLC12A4,INTS9,SNRPN,ATP10B,POGZ,NEK4,SUPT5H,SYP,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TIAM1,ERCC6L2,METTL3,PPIL6,ZKSCAN5,UGT8,P2RY12,CLDND1,ZXDA,WNK3,PDSS2,SMIM8" MicroRNA hsa-miR-512-3p:PITA hsa-miR-512-3p:PITA_TOP PITA 9.21E-36 5.16E-32 2.96E-35 2.73E-34 66 266 "PTCHD1,PCDH19,RTL9,SPOP,PITPNM2,LRFN1,ATP2B2,CACNA1A,PTBP2,LRBA,FOXN3,B4GALT6,CNR1,ZNF385A,ARHGEF10,IP6K1,SGSM2,HIPK3,MBNL2,KMT5B,PAN3,ERBB4,FGF13,AFF2,OGA,CHL1,PTPRT,KAT7,HLF,NCOA7,SMAD9,MAT2A,MBNL1,MXI1,MYT1,NEK1,NALCN,TRHDE,PPARA,PPP2R5E,PPP3CA,PKIA,MAPK10,TMEM260,USP47,SBF1,ATXN7,CPEB4,TMCC1,SP2,CDK19,SS18,ERBIN,CAMTA1,TAL1,TCF4,TRIM2,AKTIP,RELL2,NR2E1,ZNF711,CADM2,MARCH8,KAT6A,ADAMTS10,ST8SIA2" MicroRNA hsa-miR-1259:PITA hsa-miR-1259:PITA_TOP PITA 1.01E-35 5.63E-32 3.24E-35 2.98E-34 71 312 "ALCAM,FAM135A,CACNB4,PTBP2,DGKI,SEPT7,FOXN3,CNR1,PREPL,LRIG1,DOCK4,MYEF2,DNM1,YAF2,MBNL2,RCAN2,NRN1,AFF2,NBEA,GATM,PCDH17,GHR,FAM19A2,BVES,MAP4K5,SMAP1,KCND2,HECTD2,MAP2,MEF2C,PCDH9,PRTG,PDPK1,GNG2,PIK3R1,IRX1,MAPK4,QRICH1,PTPRB,PTX3,RDX,ZFHX4,SCP2,CASC3,SH3BGR,FNDC3A,WDR47,SEPHS1,CPEB4,FAM126B,PDZRN3,KDM3A,LARP4,ERBIN,NECAB1,CAMTA1,SATB2,DICER1,ZFPM2,AKTIP,KAT6B,SGK3,KCNT2,CADM2,PRDM8,TUBA1A,FZD3,HNRNPA3,KLHDC1,SOCS4,SENP7" MicroRNA hsa-miR-1261:PITA hsa-miR-1261:PITA_TOP PITA 1.03E-35 5.79E-32 3.32E-35 3.06E-34 62 232 "PWWP2A,ZNF608,ALCAM,ZBTB10,ATP2B2,CALB1,USP6,SEPT7,CFL2,SOCS6,ARMCX2,RHOBTB1,RAB39B,CPEB2,EGR3,EIF4G2,PLEKHA1,ERBB4,ETV1,EYA1,NBEA,TOX3,PCLO,PSIP1,MIER3,GABARAPL2,NEGR1,CREG2,TTYH2,MEF2C,MEIS1,MXI1,ZC3H12B,NF1,PCDH9,SNX10,STRN3,PTPRD,RGS4,SEMA6D,SATB1,SCAF8,CCDC92,SEPHS1,CCDC88A,TMCC1,UNC5B,ITPRID2,ERBIN,TACC1,CUX2,FRYL,TRPS1,USP1,KCNK12,ZIC1,ZIC2,POLR3H,NAV3,WNK3,FZD3,KAT6A" MicroRNA hsa-miR-33b*:mirSVR_highEffct hsa-miR-33b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-35 5.89E-32 3.38E-35 3.11E-34 96 577 "CLK4,NCKAP5,ADCY6,KIAA1324,SMIM17,ARHGAP20,OGT,EP400,ADAM23,SGCE,CA4,RCBTB2,TPP1,IQCK,ARMC8,AKAP6,CLOCK,CS,PDE4DIP,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,ARMCX4,ZNF804A,SNAP91,NR1D2,PDCD6IP,DNM1L,PHF20L1,MRNIP,RGS17,DCTN4,EPB41,SRRM1,FGFR1,SUCO,HPCAL4,TMEM107,UFM1,KIAA1841,RAB30,FAM19A2,SOX21,PSIP1,HSPA1L,ZNF678,LMO2,MAT2A,MATN3,MBD1,ZNF680,ZNF92,MYO6,SFR1,NF1,PRTG,MTRF1L,RETREG2,PPP3CA,BDNF-AS,PTPRB,PTPRG,FAT4,RASGRF2,ZFHX4,CYB561D1,NEK11,CSRNP3,HSPA4L,NUBPL,DHX30,CMTR2,USP33,BDP1,ITPRID2,SSTR1,RGL1,KANK1,SYT1,ANKRD28,MCF2L,TCF12,SYNE1,DOCK9,NPL,ANKRD20A2,TSC1,WIPF1,SMARCAD1,DHX33,DNALI1,LINC02210,UBE3B" MicroRNA "ATGTACA,MIR-493:MSigDB" "ATGTACA,MIR-493:MSigDB" MSigDB 1.15E-35 6.46E-32 3.70E-35 3.41E-34 69 294 "FMNL2,UNC5A,PCDH19,OSBPL6,SRPX,PHF12,MADD,TMEFF1,NCOA1,RASL11B,ATP2A2,BCL7A,CAPN3,USP6,DGKI,CDH2,SRSF11,NRXN3,LRIG1,SV2B,E2F6,TMTC1,PHF20L1,MBNL2,EYA1,TAOK3,FGF13,PSD2,NBEA,USP21,GABRG2,GAD1,AHDC1,SOX21,MARK1,MEF2C,GIT1,PDE4D,PDPK1,NLGN3,PIK3R1,PCDH18,PMP22,LRP12,PPP2R2C,RBBP6,FIGN,ZNF532,RPE,SALL1,FHOD3,NLGN1,MAST1,MBD5,PDZRN3,SP4,LARP4,SS18,ANKRD28,ADGRL3,CLASP1,SYNE1,DOCK9,PUM2,TRPS1,EIF4ENIF1,UBE3A,ZIC1,ZIC2" MicroRNA hsa-miR-129*:mirSVR_highEffct hsa-miR-129*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.15E-35 6.46E-32 3.70E-35 3.41E-34 93 543 "ACADM,XKR4,NDRG2,FMNL2,KLHL13,HFM1,NAE1,BTK,JAZF1,PTBP2,USP6,DGKI,HECTD1,COL9A1,LETMD1,ABI3BP,COX4I1,RBM39,VAC14-AS1,DOCK4,SPATA2,RHOBTB1,SACS,GOLT1B,E2F5,EDNRB,PHF20L1,RCAN2,F5,ZSCAN30,MED12L,POLK,ANKFY1,NOP56,AKAP3,DISC1,GRIK4,GRIN2D,PRDM5,FRMD3,FAM69A,KHK,KIF5A,PAXBP1,HECTD2,PIK3AP1,MMP16,MYO9A,NINJ2,GPR137C,GLIPR1L2,CYTL1,TRHDE,PKIA,GDPD2,MTMR10,SPDL1,ERI2,RFX3,RGS12,CCDC82,SUGCT,CCDC102B,BAALC,TCP11L1,MEG3,HUNK,RYR3,NCBP3,CASC3,FRMPD1,ABLIM3,DHX30,SLC9A5,BDP1,ATP10B,SS18,ERBIN,ANKRD12,SLC19A3,FRYL,PMS2CL,TIAM1,HEY1,TRIO,TRO,RPL7L1,FAM155A,FLRT2,PRDM8,PLSCR4,PHTF2,LAS1L" MicroRNA hsa-miR-6785-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-35 6.57E-32 3.76E-35 3.47E-34 116 825 "XKR4,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,HAP1,CAMK2A,ISPD,CBS,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,RASA4,PLEKHA1,MRNIP,IGSF6,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,AGBL5,ZNF491,SOWAHA,IGF1,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,MSI1,NBL1,NFIX,NOVA2,SLC11A2,TBC1D25,OGG1,ZNF713,GPR173,PFKFB3,CCSER2,RETREG2,PPP2R2B,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,CEP97,SH3TC2,IQSEC3,PRRT2,MORC4,PGBD4,EMID1,HES6,MYO18A,PEX26,PKNOX2,ZKSCAN3,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,ERCC6L2,SSBP2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,PARP11,TMEM63C" MicroRNA hsa-miR-6883-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-35 6.57E-32 3.76E-35 3.47E-34 116 825 "XKR4,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,HAP1,CAMK2A,ISPD,CBS,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,RASA4,PLEKHA1,MRNIP,IGSF6,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,AGBL5,ZNF491,SOWAHA,IGF1,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,MSI1,NBL1,NFIX,NOVA2,SLC11A2,TBC1D25,OGG1,ZNF713,GPR173,PFKFB3,CCSER2,RETREG2,PPP2R2B,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,CEP97,SH3TC2,IQSEC3,PRRT2,MORC4,PGBD4,EMID1,HES6,MYO18A,PEX26,PKNOX2,ZKSCAN3,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,ERCC6L2,SSBP2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,PARP11,TMEM63C" MicroRNA hsa-miR-129-5p:Functional MTI Functional MTI miRTarbase 1.18E-35 6.58E-32 3.76E-35 3.47E-34 100 625 "AS3MT,GALNT13,TEX22,MTA3,PCDH19,KCTD16,TAOK1,SEMA6A,CEP126,APC,ARSE,MARCH3,NCOA1,SLC2A11,BCL7A,BID,CALM1,ISPD,CBS,TBRG4,LETMD1,AKAP5,RTTN,CLOCK,HAPLN1,RNF14,ANKRD44,ABCG1,VCAN,USP6NL,KIAA0408,JAKMIP2,TIAM2,ZC3H11A,DNAH9,ABCC5,EBF1,KLHL5,ACSL4,TAOK3,UFM1,BRSK1,SRCAP,NTNG2,GLUL,POLL,GNAL,PRRC2B,RNF165,FAM107A,SLC2A6,HNF4G,ZDHHC15,IGF1,SCIN,IBA57,CYP27C1,L1CAM,LIMS1,GPR155,MBD1,NPTX1,PDE3A,PDPK1,ABCB1,ZNF655,SMIM7,STRN3,PPARA,CEP41,CNTLN,MTMR10,NKAIN1,ZNF793,NWD1,RET,FIGN,GSTCD,ELP2,KCNIP3,SATB1,SCN2B,SH3BP2,FNDC3A,EPN2,EPC1,RBM26,CAMTA1,KIAA0930,SLC44A1,FAM124A,PARD3,KAT6B,RUNDC3B,TRPS1,VLDLR,ZNF708,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-3189:mirSVR_highEffct hsa-miR-3189:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-35 7.48E-32 4.28E-35 3.94E-34 90 510 "DGCR6,GALNT13,ADGRF5,CCDC146,PKP4,NUMB,SCAPER,CFAP410,ARHGEF25,LDB2,CFL2,CHGB,IQCK,HINFP,SIPA1L1,KIAA0040,ZFYVE16,ELMSAN1,SNAP91,SPOCK3,WDR20,DMD,F5,CORO2B,FGF12,IP6K2,NOP56,FLYWCH1,EFCAB2,ST6GALNAC3,BRSK1,ZMAT1,GAD1,DISC1,TUBGCP4,SULT1C4,USP19,LUZP2,PLPP7,KAT7,DDX19B,LINC00634,LMO2,ASPRV1,MARK1,TM6SF1,MXI1,NCF2,DNHD1,CNTN3,NALCN,EXOSC10,PILRA,SH3KBP1,PPP3CA,SNRK,MTMR10,PTPRD,RFX3,ARMC5,ROBO2,RPE,ATP8B4,ATAT1,CASC3,MRAS,ST6GAL1,MBD5,KDM4B,UNC5B,ST5,ZSCAN29,FBXW11,PCDHB10,TK2,ASXL3,PIK3R5,TRO,SSBP2,CLHC1,RPL7L1,UBE3A,MICU3,ZNF540,AGMO,EML6,ANKS1B,SPIRE1,DOCK8,IFT88" MicroRNA hsa-miR-218-1*:mirSVR_highEffct hsa-miR-218-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-35 9.14E-32 5.22E-35 4.81E-34 107 713 "NCKAP5,SYS1,CEP126,ABCD2,SUGT1P4-STRA6LP-CCDC180,TTLL9,BID,KALRN,PTBP2,CAPN3,SPAG9,ARHGEF2,SEPT7,LRRFIP1,PLAA,ARMC8,ZFP28,NCOR2,SIPA1L1,PDE4DIP,SLITRK5,APPL1,ZSCAN23,HDAC9,IP6K1,JAKMIP2,MFAP3L,EDIL3,KMT5B,ZNF549,MRPL37,PTK2B,CEP78,FER,FGF1,FGF12,FGFR1,POMT1,GABBR1,TCERG1,TNRC6A,DCLK2,WDFY3-AS2,ADGRA3,AP4S1,RNFT2,ELOVL5,ZNF678,NME9,KCND2,KCNN3,KHK,MAP2,KCTD6,THYN1,IGSF11,OCRL,CHAMP1,PCSK5,GNG2,PFKFB3,OLA1,PLCL1,ANKRD16,MINDY2,PKIA,MAPK9,MAPK10,CNTLN,ZSCAN2,RASGRF2,RFX2,RIC8B,CCDC82,SAFB,SEMA6D,FNIP1,PEAR1,SH3GL3,FERMT1,NLGN1,SLC12A2,IFT122,DOP1A,MYCBP2,ZC3H13,SPART,CLASP2,ADHFE1,KANK1,SYNE2,C12orf76,TACR1,ADGRL3,PCDHB9,SLC19A3,PUM2,ERCC6L2,CDK20,VLDLR,MKRN3,ZNF138,EML6,LINC02210,HPS4,ITM2C,CASC15" MicroRNA hsa-miR-1976:mirSVR_highEffct hsa-miR-1976:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-35 9.75E-32 5.57E-35 5.13E-34 98 604 "SUGT1P4-STRA6LP-CCDC180,PPP4R4,MARK4,TTLL9,RGS11,CBR1,DIS3L,AKAP6,BAG4,CREM,NCOR1,CSF2RA,CSNK1G3,PHACTR3,CTH,RIMS2,CYBB,CENPL,USP3,KCTD3,GPHN,NRN1,SCML2,GTF2IRD2,SPSB4,POLK,GHDC,KIAA1841,TXNL4A,STARD3,LUZP2,LOXL3,PCLO,FAM19A2,FRMD5,RBPJ,DISP2,GPR62,PACRG,GPR155,ZNF667-AS1,AQP11,MATN2,MEIS2,MMP16,CCDC13,NFE2L2,PRTG,PDE4D,GNG2,RETREG2,SEPT4,ZSCAN32,CCDC40,OXR1,SETD5,CARF,GALNT10,FERMT1,PPP4R3A,SLC6A11,MAST1,RCOR3,IFT122,ANKRD36,MBD5,ZSWIM8,ZC3H13,RBM26,MPRIP,KANK1,SULF2,STXBP1,NECAB1,TACC1,PJA1,TBCEL,MGRN1,NAT16,ARHGAP9,HIF3A,AP4E1,AKTIP,R3HDM1,KAT6B,TPM1,PPIL6,EIF4ENIF1,USP1,ZNF709,CCDC136,ATP6V0E2,ZNF138,MEIS3,EMSY,NAV3,FIP1L1,CASC15" MicroRNA hsa-miR-494-3p:TargetScan hsa-miR-494-3p TargetScan 1.79E-35 1.00E-31 5.73E-35 5.27E-34 84 446 "ADCY5,ADCY6,PLEKHH1,PTCHD1,BEND6,MTUS1,OSBPL6,PCDH10,APC,IGDCC4,ARNTL,BACH1,CAST,CBS,CCNT1,DCLK1,DLGAP1,CNR1,FAM171B,CLOCK,RBM39,PLCXD3,PYGO1,DNAL1,JAKMIP2,DPYSL2,EIF5,EIF1,RCAN2,CELF1,GHR,PPARGC1A,PRRC2B,IRAK3,HAS2,NCKAP1L,ARHGAP36,ELOVL5,NEGR1,AGFG1,IGF1,IL6ST,KIF2A,KIT,MAT2A,LRP1B,NOVA1,GPR137C,PCSK1,PPP2R2B,PRKAB2,CEP41,MAPK10,DIRAS2,APTX,ANKHD1,PTPRB,RAD51D,RASGRF1,MSANTD2,GTDC1,PBRM1,RORB,CSRNP3,FBXO11,FHOD3,PEX26,CXXC4,MBD5,NMNAT2,ARHGAP26,PLCB1,CLASP1,NSD1,ITGB3BP,ASXL3,POLR3H,ANKS1B,LAMP5,DHX33,EVI5,HNRNPA3,NETO2,GAN" MicroRNA hsa-let-7b:mirSVR_highEffct hsa-let-7b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.81E-35 1.01E-31 5.76E-35 5.31E-34 112 777 "KLHL32,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,CH25H,TAOK2,NDST3,PPT2,QKI,MAP4K4,IQCK,AHCTF1,IGDCC3,OSBPL3,DAPK1,B3GAT3,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,APH1A,AASS,EIF4G2,LRRC17,RACK1,PPP1R1B,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,CNTRL,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,NKD1,RBPJ,FAM69A,NME9,MEIS2,CNOT4,NOVA1,OGG1,XRN1,EPB41L4B,PKIA,GDPD1,MASP1,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,FNIP1,KIF27,FNDC3A,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCEA1,CDH22,MTMR14,FAM124A,TPM2,PDSS1,RICTOR,LYPD6,SMARCAD1,STOX2,PHTF2,GAN" MicroRNA hsa-miR-191*:mirSVR_lowEffct hsa-miR-191*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.08E-35 1.16E-31 6.63E-35 6.11E-34 95 570 "KCNH8,ABHD6,XKR4,ADD1,ADORA2A,OLMALINC,AGT,OSBPL1A,CC2D2A,PPFIA3,ZFYVE28,MARK4,NCOA1,SLC4A4,DPY19L3,BCHE,NRP2,CACNA1I,MYRF,CA12,VXN,RUNX1T1,CACNA2D2,CHRNA4,NRXN3,TPP1,CNN3,CNTN1,AKAP5,MYRIP,CNRIP1,SNCAIP,PDE4DIP,LIN54,SPOCK2,RPS6KL1,DPH1,PDCD6IP,DUSP9,PHC2,HEYL,ELN,MFSD10,ANKMY1,FCGR3A,FCGRT,FGF1,AGAP3,CHL1,TUBGCP4,PPARGC1A,GNAL,PRRC2B,CACFD1,GRM2,PACSIN2,SHISA6,FAM95B1,INPP5B,ASPRV1,MEIS1,PTOV1,OPRL1,SEMA5B,SCHIP1,MINDY2,PRKCB,RELN,NDUFS7,PTPRN2,RAD51D,KLHDC8A,CCDC25,ATXN2,SCN7A,FHOD3,ABLIM3,SMARCA4,ZSWIM8,PEG10,SPTB,ADHFE1,VPS13A,SYT1,TACR1,RNF216P1,DICER1-AS1,ZMAT3,ACTR6,LRRC8A,TRO,TTTY15,NPDC1,CASC15,JPH3" MicroRNA hsa-miR-1468:mirSVR_lowEffct hsa-miR-1468:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-35 1.27E-31 7.24E-35 6.67E-34 94 559 "FMNL2,AK2,EPB41L5,MAGEE2,ARNTL,RGS20,MARCH3,ADGRB3,CACNA1A,USP6,SCARB1,C1orf52,CDH2,TIGD7,CHN2,PPT2,FBXO7,C4orf33,CNTN1,IQCK,COL11A2,GDA,CNTNAP2,RASGEF1C,TM9SF4,KIAA0319,SV2B,FAM107B,EMX2,CLVS1,GORAB,MED12L,AFF2,KHDRBS3,ZMAT1,ERAP1,GCNT2,BTN2A1,COQ10A,BVES,LINGO1,RNFT2,AGBL5,SMAP1,EID2B,KIAA1755,KIF2A,HECTD2,NEXMIF,SETD4,P2RX7,NLGN3,PMP22,MBOAT7,MINDY2,KANSL1,MASP1,DEF8,PIGG,PTPRG,CEP97,ZNF793,KHDRBS2,ZDHHC14,GAL3ST4,LGI2,ROBO2,ZNF354C,SBF1,FBXO11,SLC11A1,TMCC1,DOP1A,KDM3A,TEX2,CLASP2,ZC4H2,SS18,SULF2,TRIM2,HIF3A,SLC44A1,ENHO,TIAM1,TMPO,RUSC1,TSC1,LINC00689,VLDLR,GAL3ST3,NAV3,MRPL47,UBE3B,MSRB3" MicroRNA hsa-miR-1292:mirSVR_lowEffct hsa-miR-1292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-35 1.31E-31 7.46E-35 6.87E-34 99 618 "ABR,SYN3,PLEKHH1,LRFN2,OSBPL1A,SORCS2,ZNF578,GPRASP2,FGD2,PPFIA4,CPNE5,SPTBN4,LINC00173,ADGRB2,SGCE,CAMK2B,ZBED1,LOC730101,SRSF11,NDST3,PPT2,STOML1,CCDC151,SUMF2,CPS1,CRY2,ANKRD44,RUBCN,MYADM,IP6K1,YTHDC1,DMTF1,SLC12A6,HIPK3,GOLGA7,COPS4,EIF1,SRRM1,TUBB3,SCML2,CHST15,FCGR3A,FGF14,FOXF2,SYNCRIP,ZNF605,DISC1,SEPT9,LRRC37A6P,KIAA1841,GATM,MSTN,MSL3,CACFD1,PADI2,CPT1C,MYLK2,ITPKA,KIFC3,LINC00634,TTYH2,LAMP2,MARK1,MEIS2,AFDN,CNOT4,NOVA1,NRCAM,LOC100128398,KCTD15,FAM216A,MAPKAP1,MBOAT7,VSTM2L,CEP41,RELN,TMEM260,ROBO2,RXRA,AP1AR,SCP2,FBXO11,FHOD3,PPP4R3A,KDM4D,ARFGAP1,ANKFN1,ATP10B,PHLDB1,STX1A,STXBP1,TPCN2,TIAM1,ERCC6L2,PPIL6,FAM155A,FLRT2,PLEKHH2,NETO1" MicroRNA hsa-let-7e:mirSVR_highEffct hsa-let-7e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.36E-35 1.32E-31 7.51E-35 6.91E-34 114 805 "KLHL32,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,SLC4A4,ZNF583,BACH1,GYG2,NDST3,C7orf61,PPT2,QKI,MAP4K4,AHCTF1,IGDCC3,ZNF385A,OSBPL3,DAPK1,B3GAT3,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,RASGRP1,FAM13A,APH1A,AASS,EIF4G2,LRRC17,RACK1,FCGRT,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GALNT15,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,CNTRL,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,LRRC25,NKD1,NME9,MEIS2,CNOT4,NOVA1,OGG1,GPR85,XRN1,POLR2F,PKIA,GDPD1,MASP1,PTK2,TMEM255A,RDX,DPF2,ERI2,FIGN,RGS3,RGS12,RIC8B,SETD5,C12orf49,ROBO1,ATP8B4,MEG3,ST6GALNAC6,CLIP1,FNIP1,KIF27,FNDC3A,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,ANKRD28,TCF12,CDH22,MTMR14,FAM124A,TPM2,PDSS1,RICTOR,LYPD6,SMARCAD1,STOX2,UBE3B,PHTF2,GAN" MicroRNA hsa-miR-181c*:mirSVR_lowEffct hsa-miR-181c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-35 2.08E-31 1.19E-34 1.09E-33 87 483 "KIAA1324,AMPH,ANK2,EPB41L5,ZFYVE28,ARNTL,PDE8B,ADGRB2,GYG2,DGKI,MS4A7,AKAP7,CNRIP1,RBM39,ANKRD44,PDE4DIP,KIAA0040,UBXN2A,CTH,DOCK4,GAPVD1,KIF26A,RASSF2,KCTD8,DGCR5,NR1D2,RCAN1,DTNA,ABCC5,EDIL3,PHF20L1,EIF4G2,LRRC17,PRMT5,OLFM1,FOXO3,ATP13A4,FLYWCH1,DOT1L,GABBR1,GHDC,IQGAP2,LRRC37A6P,MSTN,SESN1,STARD3,ADGRA3,GPD2,FRMD3,DDX19B,METTL21A,STXBP5,MID1,CNOT4,IGSF11,PDE4D,XRN1,FAM216A,PPM1B,MASP1,PTPRE,NKAIN1,PID1,ENOX1,ERI2,GTDC1,RFX3,ZFHX4,NEK11,ZNF568,SEMA6D,KIF21A,ANKRD6,SEPHS1,SLC8A1,SLC12A2,RBM34,SP4,ZNF423,TAL1,TMPO,PDSS1,VLDLR,LYPD6,WNK3,ACTR3B,FAM219B" MicroRNA hsa-miR-143:PITA hsa-miR-143:PITA_TOP PITA 3.75E-35 2.10E-31 1.19E-34 1.10E-33 60 220 "KCNH8,TMEM132B,NUMB,CACNA1A,CALM1,LRBA,DCLK1,SRSF11,TAOK2,AKAP6,SLC35F1,CSNK1G3,DMTF1,SLC12A6,PAN3,ETV1,FGF1,UBE2E3,SYT3,CPLX2,GATM,GPD2,RNF165,KAT7,MIER3,KCND1,MEF2C,MYO5A,MYO6,NEXMIF,CNOT4,TMOD2,PLIN1,STRN3,LRP12,RETREG2,RASGEF1B,MAPK7,PTPRB,KCNIP1,COPZ1,SCAF8,PPM1E,TET1,ARHGAP26,LARP4,STXBP1,NUDT10,ANKRD28,ANKRD12,WSCD1,TMEM121,TIAM1,SLC35A4,KLC2,MKRN3,ZBTB38,TMEM237,NAV3,PHTF2" MicroRNA hsa-miR-1324:PITA hsa-miR-1324:PITA_TOP PITA 4.11E-35 2.30E-31 1.31E-34 1.20E-33 72 328 "ASIC1,ADCY6,TAOK1,SEMA6A,SPOP,ALCAM,ARHGAP20,APBB2,ATP2B2,CALB1,CAMK2A,MAGI1,FOXN3,TAOK2,AKAP5,ARHGEF10,UBXN2A,SNPH,HDAC4,YTHDC1,SNAP91,DLX1,CPEB2,HIPK3,GPHN,SPEG,ST3GAL6,SUCO,AFF2,SYT3,TMEM107,CSPG5,FERMT2,KAT7,BACH2,HLF,AGFG1,IPO5,CAMK2N2,MAPT,MAT2A,KITLG,NFIX,IGSF11,CLDN11,ZNF827,PCDH8,PDE1C,PMP22,LRP12,CNNM2,TMEM260,REV3L,FIGN,CASC3,KIF21A,CPEB3,WDR47,SLC8A1,SLC12A2,TMCC1,ZSWIM8,PLCB1,SYN2,SYP,SYT1,NR2C2,FAM155A,OSBP2,CELF4,EMSY,KAT6A" MicroRNA hsa-miR-217:PITA hsa-miR-217:PITA_TOP PITA 4.67E-35 2.61E-31 1.48E-34 1.37E-33 71 319 "KCNH8,INTS2,SEMA6A,USP37,SLC4A4,ADGRB3,LDLRAD4,SEPT7,DLGAP2,CHN2,QKI,CNR1,COL4A5,RBM39,KIAA0408,DOCK4,YTHDC1,MYEF2,CPEB2,RCAN1,EDIL3,YAF2,PAN3,EPHB1,ACSL4,FGF11,FOXO3,AFF2,FAM49B,SARAF,PCDH17,MIER3,STXBP5,NCOA7,MXI1,ZC3H12B,NF1,NNAT,NOVA1,CNTN3,GDPD1,FIGN,RTN1,SATB1,HSPA4L,PPM1E,FBXO11,WDR47,GKAP1,SOX11,LARP4,STX1A,ZC3H4,SYN2,TACC1,ADGRL3,FBXW11,ZEB1,RPGRIP1L,SIRT1,TLR4,TBC1D15,VSNL1,ZNF711,MICU3,REEP1,STOX2,TMEM178A,HNRNPA3,FXR1,SENP7" MicroRNA hsa-miR-3176:mirSVR_highEffct hsa-miR-3176:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.84E-35 2.71E-31 1.54E-34 1.41E-33 92 541 "NCKAP5,ADD2,KCTD16,UNC79,FAM135A,AMPD3,TNRC6C,LINC00173,CDK13,ZSCAN18,NUMB,SLC2A11,DST,JAZF1,IL33,CALB1,USP6,KCNAB3,TIGD7,LY86,AKAP7,SLC4A8,MYRIP,ZFP28,SEC31B,CST3,ARMCX4,DOCK2,SLC12A6,DPP6,FARSB,PLEKHA1,NRN1,GORAB,GTF2IRD2,FGF14,POLK,POMT1,CGREF1,DOT1L,COPS8,RAB30,VSIG4,ZNF181,DISP2,LIMS1,NCOA7,TM6SF1,NF1,SLC11A2,OCRL,GPR85,PKM,FAM216A,PLIN1,SEPT4,TMEM104,TMEM260,FAT4,MORC4,GTDC1,PBRM1,CARF,MCMBP,GLDN,HSD11B1L,CLIP1,AP1AR,SP4,SSTR2,ERBIN,SYNE2,COBL,ADGRL3,PCDHB4,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TIAM1,NR2E1,R3HDM1,TP53BP1,PLEKHH2,GUSBP1,TRIM9,IFT88" MicroRNA hsa-miR-3191:mirSVR_lowEffct hsa-miR-3191:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.62E-35 3.15E-31 1.79E-34 1.64E-33 92 542 "SYN3,AP2A2,AK2,UNC79,PKP4,SFMBT2,ARNTL,PDE8B,CHID1,KSR1,DST,CALB1,ARHGEF1,ZMYM4,EVI5L,TPP1,QKI,FHL5,IQCK,TBPL1,CLIP3,CS,GPSM1,RUBCN,ARHGAP32,DAPK1,DPH1,ARRDC4,PHF20L1,RASA4,FCGR1B,ZNF589,IP6K2,AGAP2,EVL,FLT1,ERGIC3,FYN,GRB10,C1QL4,ADAMTS13,GRIN2D,SLC2A6,ATXN2L,MSL1,ZNF678,KCNN1,PAXBP1,MEIS1,MSI1,FXYD7,NFIX,NINJ2,PALM,PDPK1,PFKFB3,KCTD15,SLC25A23,PILRA,KANSL1,ELOVL2,PTPRE,PTPRG,SLC25A48,ZDHHC14,DUSP15,PRIMA1,ARMC5,RPE,MCMBP,SGSM1,RYR3,LIMS2,SEPHS1,SNRPN,SPTB,TSPYL2,MESP1,SSPO,TTBK2,TMEM150C,SIN3B,RPGRIP1L,PHF24,SLC19A3,CYB561A3,LRRC8A,TNS1,AMACR,VGF,RICTOR,PHTF2" MicroRNA hsa-miR-544:PITA hsa-miR-544:PITA_TOP PITA 5.73E-35 3.21E-31 1.82E-34 1.67E-33 83 442 "CCDC85A,CASKIN1,PCDH19,WDR35,OSBPL8,SPOP,ALCAM,ARHGAP20,AMPH,DPP10,MARK4,ATP2A2,MPDZ,CACNA1G,CACNA1A,CACNB4,CALM1,CAMK2B,CAMK2G,CBFA2T2,CDH2,DLGAP2,SOCS6,PCYT1B,RBM39,GAPVD1,DAPK1,ALKBH8,SACS,CPEB2,ARRDC4,DNM1L,FRY,MBNL2,PAN3,GPHN,FGF12,PCDH17,PPARGC1A,KDM2B,HTATSF1,PCLO,GRB10,ADAMTS6,HLF,SMAP1,RBPJ,MAP2,MBD1,NELL2,NFYA,CNOT4,NOVA1,GPR85,PIK3R1,IRX1,RANBP3L,TMEM260,RET,MCMBP,SEMA6D,SATB1,HSPA4L,SCAF8,CPEB3,EPN2,WDR47,CPEB4,FAIM2,SOX11,SP4,ERC1,CLASP2,PRRC2C,TAL1,TBL1X,TCF4,SLC35G2,AKTIP,TUBB1,UGT8,DNAH10,GAN" MicroRNA hsa-miR-3184:mirSVR_highEffct hsa-miR-3184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.76E-35 3.22E-31 1.83E-34 1.68E-33 95 577 "SYS1,ADRA1B,DPY19L2P4,AP2A1,ZNF608,SPOP,FAM135A,CDK13,ATP6V1G2,ADAM15,BTK,KALRN,USP2,CPNE6,PPT2,CLTB,AATK,PDE4DIP,DGKB,DBI,SPATA2,HEPH,LYPD1,DDX46,TMCC2,FCF1,YAF2,EGFR,USPL1,EIF1,EPHB1,RAB9B,SIRPB1,EZH1,PTK2B,FGFR3,AGAP3,CGREF1,CHL1,B4GALNT1,LRRC37A6P,RUNDC3A,GLYR1,GLUL,POLL,STON1,GRIN2D,AP4S1,HSPA1L,INPP5B,MN1,NNAT,SLC11A2,GPR173,ZNF655,PLTP,EPB41L4B,PPARA,PKIA,MAPK10,BCAS3,CNTLN,TMEM260,PTPRB,YY1AP1,ST6GALNAC6,FERMT1,HKDC1,AMBRA1,SLC4A3,SLC14A1,SLC22A4,KDM4C,ERC1,SPART,ATP10B,RGL1,STXBP1,PLCB1,SMG6,NAT16,OBSL1,USP32P1,RELL2,PRRT1,DCBLD1,RPRM,OSBP2,ZNF177,EML6,DNALI1,LINC02210,HPS4,CASC15,MSRB3" MicroRNA hsa-miR-604:mirSVR_lowEffct hsa-miR-604:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.03E-35 3.37E-31 1.91E-34 1.76E-33 91 531 "EMILIN3,NCKAP5,SYS1,GALNT16,BEND6,HECW2,ALCAM,USP37,SEMA4G,LINC00173,NCOA1,DYNLL1,RIPK1,AP1M1,CA4,CAMK2G,PRC1,DCLK1,IGDCC3,SEC31B,NCOR2,PDE4DIP,DZIP3,CTH,RUBCN,ARMCX4,LYPD1,DNM1,RPS6KL1,CPEB2,TMTC1,ING4,EPB41L2,ERCC2,ZNF461,POLK,FOLH1,NBEA,RASL10A,CELF1,SEPT9,RNPS1,CCDC184,ADAMTS13,CIT,CLASRP,PSIP1,ICA1,MYLK2,NME9,HECTD2,MYT1,NPY,NPTX2,PCSK5,PFKFB3,PLIN1,PPP3CA,CASTOR1,CCDC40,FAM66C,GTDC1,ZFHX4,S100B,SEMA6D,SCN8A,FOXRED1,SH3GL3,SHMT2,SLC11A1,RCOR3,PDZRN3,PBLD,SS18,SSPO,SYNE2,SYN1,CAMTA1,TAL1,SMG6,HIF3A,TK2,R3HDM1,SMUG1,UBE2H,CLIP2,NPDC1,XRCC4,ANKS1B,RNF170,NETO2" MicroRNA hsa-miR-1229:mirSVR_highEffct hsa-miR-1229:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.09E-35 3.41E-31 1.93E-34 1.78E-33 100 637 "EMILIN3,GALNT13,WDR35,AK2,DPP10,APC,PPP4R4,SPTBN4,ARNTL,MARCH3,NUMB,DDR1,CACNB4,KALRN,RUNX1T1,CBR1,QKI,ZFP28,SEC31B,CTH,DCAF8,SPOCK2,MFAP3L,FBXL5,CHRDL1,RCAN1,E2F5,EBF1,KMT5B,EIF4G2,SIRPB1,FAM198B,FDFT1,SEC24B,SEC23B,OGA,CHL1,GABRG2,GAD1,ZNF559,WASHC2A,GHR,GPR12,FAM19A2,TNFAIP8L3,CELF5,MATN2,ZNF680,CNOT4,SLC11A2,DUSP26,PLCB2,PLCL1,ING3,SEPT4,SNRK,CNTLN,TMEM260,PTPRD,PEX2,RAD51D,ZNF493,ZFHX4,RORB,ZNF568,SAFB,CASC3,SLC2A5,ZNF430,ARHGEF40,SLC12A2,ATF7IP,ZNF667,SNAP25,SNCA,DDN,POGZ,ZSCAN29,VPS13A,ANKRD12,ZEB1,GPRIN3,KHDC1,ITGB3BP,AP4E1,WBP2,ANKRD20A2,RPL7L1,UBE3A,ZNF781,CLDND1,RICTOR,GUSBP1,ZNF19,PROCA1,EMSY,PRDM8,PDSS2,KAT6A,ADAMTSL3" MicroRNA hsa-miR-299-3p:mirSVR_highEffct hsa-miR-299-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.06E-35 3.95E-31 2.23E-34 2.06E-33 98 614 "CLK4,KLHL32,ADD1,ADD2,RTL9,FAM135A,APC,USP37,MADD,ZBTB10,TMEM108,ATP2A2,ZNF583,RGS9,KALRN,RUNX1T1,CERS5,CBFA2T2,TIGD7,CLGN,IQCK,FAM149A,SLC35F1,ANKRD44,CSNK1G3,HDAC4,BRINP1,ZBTB24,FBXL5,RHOBTB1,GRIN3A,E2F6,EDN1,PHF20L1,TMEM35A,EPB41L2,RABEPK,MRPL37,NEURL4,ZNF44,DISC1,INPP5K,GGT7,BRD8,KDM2B,FUT10,DIDO1,GRM8,KAT7,RNFT2,SHISA6,KNDC1,SLC35G1,PAXBP1,NCOA7,MBNL1,MSR1,LAYN,NF1,VWA2,NTRK3,OPA1,P2RX7,PDE3A,GNG2,FAM218A,PLTP,PMP22,SEPT4,PKIA,SLC26A11,PTPRG,TUG1,RGS4,KCTD17,SNX22,BAALC,KCNIP3,CHD9,DOP1A,SP4,ZC4H2,STAU1,VPS13A,PLCB1,TACR1,TCF4,OBSL1,FRYL,STXBP4,UBE2H,CCDC14,MAP3K12,FAM13C,UBE3B,CASC15,FRMD6,RNF146" MicroRNA hsa-miR-4324:mirSVR_highEffct hsa-miR-4324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.80E-35 4.37E-31 2.47E-34 2.27E-33 101 651 "KCNH8,AS3MT,NDRG2,ADD2,MTUS1,BIN1,APBA2,BCAS1,ZFYVE28,ARNTL,DOCK11,CAST,MAGI1,PPT2,ABCG2,SULT4A1,ARMC8,COX4I1,IGDCC3,CREM,PHF14,DAPK1,DBI,GIT2,PITPNC1,SGSM2,RAB39B,DMPK,CPEB2,DMTF1,ECM2,ABCC5,SRRM1,IGSF6,ZNF549,NRN1,SCML2,ZNF589,FGF13,SEMA4D,TMEM107,SIGLEC8,CPLX1,NEU3,TXNL4A,TCERG1,ZNF638,CBX1,STMN2,GRIA2,PRDM5,FAM19A2,HNF4G,SMAP1,NKD1,SLC35G1,KCND1,KCNN3,HECTD2,MARK3,MAT2A,CHIC1,MIA2,SLC11A2,CHAMP1,PDE4D,POLR2F,DRAM2,APTX,PTK2,TMEM260,FAM66C,RASGRF1,GTDC1,KCTD17,KIF7,ZFHX4,CCDC82,ZC3H14,MEG3,PPP4R3A,SLC14A1,ANKRD36,SNRPN,BDP1,GLT8D1,KDM4C,ATP10B,STAC2,VPS13A,TBCEL,PCDHB4,MTMR14,NPL,AMACR,TSN,LINC00689,KLC2,TRIM9,EPM2A,NETO2" MicroRNA hsa-miR-3126-5p:mirSVR_highEffct hsa-miR-3126-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-34 6.38E-31 3.60E-34 3.32E-33 94 570 "ADORA2A,ADRA1D,ADRA1B,RTL9,VAT1L,ARRB1,ATP1B3,CASTOR3,BAIAP3,IL33,SLC16A4,SEPT7,CHN2,EPS15L1,CLTB,AKAP6,ABI3BP,ZNF385A,FAM171B,CRY2,CLIP3,MROH8,CSF1,PDE4DIP,CCDC144A,ZNF337,DCTN1,DYNC1I1,DTNA,EIF4G2,C8orf37,EIF1,F5,ZSCAN30,FGFR1,ERGIC3,GABRA3,GGT7,ZNF638,LOXL3,ADGRA3,FUT10,MSL1,DISP2,IL12A,SLC35G1,KCNJ5,KIF5A,PAXBP1,PIK3AP1,MAP6,SHC3,MID1,NPR2,PCSK1,CDK18,FXYD1,POU6F1,HYDIN,SAMD9,GDPD2,TMEM260,ACSM5,EXD2,NEK11,MCMBP,KCNIP1,FAM192A,PRCD,FNIP1,ASAP3,SLC2A5,BTBD3,FAM214B,ZNF667,SS18,SSPO,SEPT3,VPS13A,SATB2,ZEB1,SYNE1,AP4E1,SLC44A1,PRRT1,PIK3R5,FLRT2,ZNF781,FTSJ1,STOX2,CIAPIN1,SLC17A7,DOCK8,HNRNPA3" MicroRNA hsa-miR-3132:mirSVR_highEffct hsa-miR-3132:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-34 6.48E-31 3.66E-34 3.37E-33 104 691 "RALGAPA1,ADD2,PLEKHH1,DPY19L2P4,MTUS1,AGT,KCTD16,TXNDC16,CARNS1,AMPH,APC,VAT1L,SEMA4G,NFS1,CD86,C1orf52,CCPG1,CHGB,CNOT8,SULT4A1,FAM149A,ZFP28,CPS1,SEC24C,ERC2,RIMS2,KIF19,DMTF1,DTNA,DNM1L,HIPK3,FRY,TMEM132E,AASS,RABEPK,MRPL37,TLR7,GMPR2,PPP1R1B,ZNF589,UBE2E3,SMC2,AP4B1,IP6K3,DISC1,TUBGCP4,SRCAP,LOXL3,GPD2,AGBL5,IDH3B,IL6ST,LIMS1,SYTL4,GPR155,MARK1,KCTD6,PAX6,DPY19L2P2,NALCN,SEMA5B,FA2H,KANSL1,GRAMD1C,GDPD2,SPDL1,PTPRN,HKR1,ERI2,MORC4,SETD5,PNMA8A,ROBO1,SPIN3,TCP11L1,RPS6KA2,LRRK2,CSRNP3,SCN8A,CHD9,ARHGEF40,TET1,SMARCC2,BDP1,TEX2,ZC3H13,SYT5,TBCEL,SIN3B,DMXL2,SATB2,FRYL,GALNT17,ICAM5,ERCC6L2,TMPO,METTL3,SGK3,FAM155A,GORASP1,NDRG4,MEIS3,EMSY,PRDM10" MicroRNA hsa-miR-648:mirSVR_highEffct hsa-miR-648:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-34 6.61E-31 3.73E-34 3.44E-33 90 524 "FAM135A,ALK,LCORL,MAP4K3,ZNF599,CALM1,PTBP2,USP6,EVI5L,CFL2,CNOT8,HECTD1,MAP4K4,SLC35F1,PDE4DIP,CTH,PUM1,DGKG,CPEB2,DMTF1,AASDH,EDNRB,PHF20L1,EMX2,CEP85L,TLR7,ADGRV1,FGF1,FGF12,SUCO,NELFCD,STAU2,OGA,FAM120B,MSTN,MALT1,GPD2,GRIA2,PRDM5,MSL1,METTL21A,KCNB1,MARK1,MAT2A,MEIS1,AFDN,BLOC1S2,NF1,NTRK3,FAM218A,PPP2R5E,SAMD9,CNTLN,RBBP6,RNH1,ROBO2,MRAP2,STK32B,ATAT1,TRAPPC13,HES6,SGK1,R3HDM2,BTBD3,SLC6A11,SLC14A1,BTBD7,ATF7IP,CPEB4,ZFP1,MBD5,KIF13A,SNRPN,POGZ,ANKRD28,DMXL2,SATB2,TEK,LRRC8A,TMPO,TP53BP2,NPL,PPIL6,DCBLD1,EMSY,STOX2,PDSS2,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-199a-5p:PITA hsa-miR-199a-5p:PITA_TOP PITA 1.32E-34 7.36E-31 4.14E-34 3.82E-33 64 259 "RALGAPA1,CCDC85A,USP31,SEMA6A,ARHGAP20,MAP4K3,SYNJ1,FUBP1,CDH2,LARGE1,CLTC,SEC24C,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,SRRM1,ERBB4,FCGRT,PRKAG2,DCTN2,MEGF10,SRRM4,GCNT2,CSDC2,PPARGC1A,TOX3,MAP7D2,GPD1,FAM19A2,BACH2,HLF,ZFYVE27,MAP2,MEIS2,MGAT3,PPM1L,AFDN,MN1,GIT1,PDE4D,TMEM255A,SH3TC2,FIGN,RORB,CLIP1,ATXN7,ZFP2,ST6GAL1,BTBD3,SOX11,SP2,LARP4,SIRT1,SLC44A1,XRCC4,STOX2,WNK3,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-362-3p:TargetScan hsa-miR-362-3p TargetScan 1.32E-34 7.36E-31 4.14E-34 3.82E-33 64 259 "RNF157,PPFIA4,GAS7,NCOA1,BCL7A,BAIAP3,PTBP2,KRIT1,CCNT1,NUMBL,PLAA,IGDCC3,CRMP1,CSNK1G3,MYADM,MATR3,DAPK1,CHRDL1,DPYSL2,HIPK3,EIF4G1,MTSS1L,CHST15,ANKFY1,PRUNE2,RNF165,DDX19B,HP,MSL1,IL6ST,KIF2A,KIF5A,IPO5,L1CAM,MGAT3,PDE3A,PDE4D,PFKFB2,OLA1,PRKACB,FITM2,CNNM2,PTPRG,C12orf49,RPE,PTGR2,SBF1,CSRNP3,BTBD3,CPEB4,MBD5,PEG10,MLST8,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,DOK6,RGMB,DPYSL5" MicroRNA hsa-miR-199b-5p:PITA hsa-miR-199b-5p:PITA_TOP PITA 1.32E-34 7.36E-31 4.14E-34 3.82E-33 64 259 "RALGAPA1,CCDC85A,USP31,SEMA6A,ARHGAP20,MAP4K3,SYNJ1,FUBP1,CDH2,LARGE1,CLTC,SEC24C,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,SRRM1,ERBB4,FCGRT,PRKAG2,DCTN2,MEGF10,SRRM4,GCNT2,CSDC2,PPARGC1A,TOX3,MAP7D2,GPD1,FAM19A2,BACH2,HLF,ZFYVE27,MAP2,MEIS2,MGAT3,PPM1L,AFDN,MN1,GIT1,PDE4D,TMEM255A,SH3TC2,FIGN,RORB,CLIP1,ATXN7,ZFP2,ST6GAL1,BTBD3,SOX11,SP2,LARP4,SIRT1,SLC44A1,XRCC4,STOX2,WNK3,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-329-3p:TargetScan hsa-miR-329-3p TargetScan 1.32E-34 7.36E-31 4.14E-34 3.82E-33 64 259 "RNF157,PPFIA4,GAS7,NCOA1,BCL7A,BAIAP3,PTBP2,KRIT1,CCNT1,NUMBL,PLAA,IGDCC3,CRMP1,CSNK1G3,MYADM,MATR3,DAPK1,CHRDL1,DPYSL2,HIPK3,EIF4G1,MTSS1L,CHST15,ANKFY1,PRUNE2,RNF165,DDX19B,HP,MSL1,IL6ST,KIF2A,KIF5A,IPO5,L1CAM,MGAT3,PDE3A,PDE4D,PFKFB2,OLA1,PRKACB,FITM2,CNNM2,PTPRG,C12orf49,RPE,PTGR2,SBF1,CSRNP3,BTBD3,CPEB4,MBD5,PEG10,MLST8,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,DOK6,RGMB,DPYSL5" MicroRNA hsa-miR-130b-3p:Functional MTI Functional MTI miRTarbase 1.32E-34 7.37E-31 4.15E-34 3.82E-33 94 571 "NCKAP5,TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,CRY2,CSF1,UBXN2A,PPP6R2,DCAF8,DAPK1,SPATA2,FBXL5,SEC16A,DPYSL2,EDN1,TMTC1,KMT5B,CERCAM,C3orf18,ERBB2,KATNAL1,EZH1,ACSL4,DLC1,FKTN,POLR1B,SEC23B,ANKFY1,CINP,MSANTD4,PPARGC1A,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ATE1,RASSF8,IGF1,ZIC5,ZNF678,KCNB1,SFXN5,MBNL1,CHIC1,CNOT4,NPTX1,GPR137C,PURG,PPARA,KANSL1,PIGG,PTPRG,ZDHHC14,PTGR2,CLIP1,SYBU,BTBD3,ATF7IP,EPC1,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,TCF4,SATB2,ZEB1,TRIM2,DICER1,GPR161,ZMAT3,SLC44A1,THRA,NACC2,RGMB,UBC,TOM1L2,VLDLR,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1,SOCS4" MicroRNA hsa-miR-4265:mirSVR_highEffct hsa-miR-4265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-34 8.93E-31 5.02E-34 4.62E-33 83 448 "CLK4,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,VAT1L,AQP6,LDHD,RUNX1T1,CLDN10,CERS5,L3MBTL4,COPB2,RAB33A,CNR1,NCOR1,SNCAIP,CSF1R,PDE4DIP,DOCK4,HDAC4,BRINP1,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,SLC37A3,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,GPD2,PADI2,ZNF546,GPR62,KCNJ16,KCNN3,PAXBP1,MEIS2,LAYN,NME4,WBP1L,CNTLN,RGS3,RGS4,CSRNP3,ATF7IP,TET1,ZSWIM8,KDM4C,LMO3,VPS13A,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,FAM13C,RNF146,SPATA13" MicroRNA hsa-miR-4317:mirSVR_highEffct hsa-miR-4317:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-34 1.04E-30 5.82E-34 5.36E-33 92 550 "KCNH8,ACADM,KLHL32,ALCAM,UNC79,MAP4K3,UPRT,RASL11B,RNF182,N4BP2L1,ADAM23,BACH1,CFLAR,ARHGEF7,FUBP1,SGCE,CAMK2G,CBS,RGN,TIGD7,CCPG1,SLC35F1,GDA,LRIG1,APPL1,PHF14,ARHGAP24,DGKB,FBXL5,KIAA0753,DMTF1,DTNA,KLHL5,AASS,SRRM1,F5,OLFM1,ATP13A4,ANKFY1,PDLIM5,STAU2,PPARGC1A,RAB30,FUT10,GRIA2,PLCD4,ATE1,GRM8,TCEAL6,SHISA6,MYLK2,LYRM9,MYO9A,FXYD7,CNTN3,PDE4D,GNG2,PIK3R1,PMP22,TRHDE,RETREG2,PPM1B,PPP3CA,PTPRO,TMEM231,MARCH1,OXR1,FIGN,ALG9,ELP2,ARX,ABLIM3,SLC8A1,SLC12A2,ATF7IP,TSPYL2,NKAIN2,SULF2,SYN2,MTCL1,CAMTA1,PUM2,SIRT1,AP4E1,RIMBP2,AMACR,TCEAL7,MAP3K12,FIP1L1,WNK3,DNAH10,FRMD6" MicroRNA hsa-miR-4254:mirSVR_highEffct hsa-miR-4254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-34 1.17E-30 6.55E-34 6.03E-33 95 586 "RALGAPA1,KCNH8,BEND6,AP2A2,CARNS1,ZNF687,UPRT,NT5C3B,ARNTL,MARK4,NCOA1,SLC4A4,ATP2B2,SYNJ1,CALB2,KALRN,CERS5,PLAA,AKAP7,LETMD1,SLC4A8,GDA,SNCAIP,CSF2RA,CYBB,KIAA0586,ZBTB24,EXOG,DMD,DPP6,DNM1L,PHC2,GOLGA7,C3orf18,SRRM1,IGSF6,MRPL10,TUBB3,IP6K2,STAU2,GAD1,DISC1,TUBGCP4,SULT1C4,DCLK2,TDRKH,STMN2,LINC01089,GABARAPL2,C2orf72,SOWAHA,KIT,NCOA7,KCTD6,MYO7A,DNHD1,SLC11A2,PCDH9,PCSK5,PFKFB3,PLCL1,POU6F1,PPM1B,PKIA,VPS13C,WDR25,TMEM145,CCDC40,TRIM68,CARF,FHOD3,NUBPL,SLC14A1,ELMO2,GKAP1,ANKRD36,KDM4B,HECW1,ITPRID2,STX1A,NUDT10,TBCEL,ZFP90,SYNE1,SLC44A1,RGMB,PPIL6,RUSC1,TSN,OSBP2,VLDLR,STOX2,ADAMTS9,TIGD6,FXR1" MicroRNA hsa-miR-30a-5p:Functional MTI Functional MTI miRTarbase 2.24E-34 1.25E-30 7.03E-34 6.47E-33 107 734 "AP2A1,OSBPL8,AK2,TAOK1,SEMA6A,MARCH4,PCDH10,USP37,STX16,ATP2A2,DPY19L3,SEC11C,ST3GAL5,CAST,CARS,SEPT7,CDH2,LRRFIP1,CCPG1,HECTD1,TBPL1,BAG4,PREPL,CREM,CSNK1G3,SACS,MTX3,TOM1,CELSR3,EGFR,MRO,MBNL2,ASB3,DCTN4,EIF1,EPB41,ACSL4,TUBA1B,TUBB3,SCML2,CHST15,SEC24B,UFM1,CELF1,MSANTD4,HHIPL1,TRAF3IP2,IP6K3,NFU1,DBF4,TNRC6A,ZNF638,GPD2,MIER3,ELOVL5,GABARAPL2,HNF4G,STMN1,LIFR,LSS,SMAD1,LYPLAL1,MAT2A,MBNL1,MPP2,HNRNPM,GNG2,PKM,EXOSC10,PPP3CA,SAMD9,REV3L,PRRT2,PBRM1,SETD5,ALG9,PCMTD2,SARS,SBF1,SLC12A2,SLC12A4,BTBD7,TET1,CPEB4,LIMCH1,RBM34,KDM3A,SP4,PEG10,LARP4,STAU1,ZSCAN29,SYPL1,SLC35G2,NACC2,TRIO,UBE2H,XPO1,MKRN3,ZFAND5,DHX33,SLC38A1,VPS35L,URM1,PHTF2,ZDHHC20,FXR1" MicroRNA hsa-miR-139-3p:mirSVR_lowEffct hsa-miR-139-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-34 1.27E-30 7.12E-34 6.56E-33 85 472 "RNF150,TXNDC16,BIN1,MADD,ZFYVE28,CADPS,TMEM108,BLM,GPR146,GPC2,CACNA1B,CBS,LDB2,ENTPD2,ZBED1,SULT4A1,CSF2RA,EDN1,GOLGA7,EPHB1,RASL12,RACK1,FLT1,SLC37A3,TPK1,RASL10A,DLL3,GAD1,GGT7,ZNF638,GP1BB,GRIA2,CACFD1,PSIP1,ARHGAP36,HNMT,LRRC25,TMEM240,KIF5A,MEIS1,MSI1,NPTX1,LOC100128398,PIK3R1,FXYD1,FSD1,ZIK1,STRC,NWD1,DUSP15,ERI2,RFX2,CARF,GLDN,STK32B,FERMT1,SHMT2,HKDC1,SEPHS1,SLC11A1,ANKRD36,CLSTN2,STX1A,STXBP1,DMXL2,CUX2,NAT16,PUM2,USP32P1,VWCE,TK2,NPL,SMUG1,TRIO,SSBP2,HIRA,UBTF,OSBP2,NPDC1,POLR3H,EML6,FTSJ1,MPPE1,UBE3B,TMEM63C" MicroRNA hsa-miR-4293:mirSVR_highEffct hsa-miR-4293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-34 1.86E-30 1.05E-33 9.62E-33 88 508 "GALNT13,MTUS1,OSBPL8,AK2,SEMA7A,ZFYVE28,RGS20,ZBTB10,NCOA1,ADGRB3,BMPR1B,KALRN,MAGI1,CFL2,PPT2,TPP1,HINFP,CLIP3,PDE4DIP,ARHGAP24,MED12,CPEB2,DMTF1,DPP6,PDCD6IP,DTNA,PHF20L1,EGFR,RGS17,FGF13,PRKAG2,IP6K2,TRAF3IP2,IP6K3,DISC1,TOX3,ADGRA3,DIDO1,GUCY1B1,MAT2A,MATN2,MID1,MYO9A,NFE2L2,NOVA1,DNHD1,SLC11A2,ZNF655,TRHDE,SCHIP1,SEPT4,HYDIN,QRICH1,TMEM260,STK32A,TMEM231,FAM66C,ERI2,ZNF532,ROBO2,EPHA10,ABCA11P,CLIP1,RMI1,ATXN2,SCN8A,CPEB3,WDR47,KBTBD4,ATF7IP,INTS9,USP33,HECW1,NKAIN2,ZSCAN29,ELOVL4,DMXL2,TCF12,FRYL,CYB561A3,ZFPM2,MTMR14,CSMD1,CFAP298,SLC17A7,DOCK8,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-425*:mirSVR_lowEffct hsa-miR-425*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-34 1.95E-30 1.09E-33 1.01E-32 87 497 "NCKAP5,TMEM132B,RNF150,KCTD16,FGD2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,PPFIA3,PCDHGB4,STX16,BACH1,CACNA1G,ARHGEF2,ZBED1,CDH2,KCNAB3,LARGE1,RAB33A,MAP4K4,SLC4A8,TCAF1,DCAF8,ZNF337,MATR3,IST1,KLHL3,DMTF1,ACOT8,TOM1,EIF1,EMX2,MRPL37,CDKL3,ADGRV1,TBC1D16,IP6K2,CAMKK2,GPD2,STON1,GRIA2,ADAMTS13,CLASRP,MSL1,ITGAM,ITPKA,KTN1,FXYD7,ALDH1L2,NFIX,PALM,PCDHGC3,ZFYVE21,PURG,PSAT1,VSTM2L,PRKAB2,BCAS3,WDR25,CNTLN,OXR1,SEMA6D,ATXN7,SH3BGR,SLC6A8,SLC12A4,SNCA,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SYNPO2,TSC1,MGAT5B,SLC30A4,FIP1L1,ST7,NLRP3,TTC7A" MicroRNA hsa-miR-1263:mirSVR_highEffct hsa-miR-1263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.97E-34 2.22E-30 1.25E-33 1.15E-32 75 369 "KLHL32,CCDC85A,KCTD16,MAP4K3,ARNTL,CADPS,ZSCAN18,NCOA1,INSYN2B,STX16,SYNJ1,MTMR2,AP1M1,METTL6,TIGD7,CHN2,NDST3,TOGARAM2,ANKRD44,DOCK4,GPRASP1,ZFYVE16,MFAP3L,LYPD1,SNAP91,RAB39B,EIF1,ANKMY1,FAM198B,GORAB,FER,SPSB4,FGFR1,RGPD5,MTHFD2,PPARGC1A,GLI2,POLL,GRIA2,ADAMTS13,VSIG4,ZDHHC15,LRRTM1,MAT2A,SRSF12,TRHDE,BCAS3,GDPD2,BDNF-AS,C1orf109,CEP97,LGI2,RORB,CLIP1,RYR3,PPM1E,FBXO11,MBD5,ZSCAN29,TTBK2,PHLDB1,ARHGEF9,PLCB1,TCEA1,FRYL,TP53BP2,SGK3,LYPD6,ANKS1B,PRDM10,PDSS2,FAM13C,HNRNPA3,CASC15,IFT88" MicroRNA hsa-miR-4296:mirSVR_highEffct hsa-miR-4296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.28E-34 2.40E-30 1.34E-33 1.24E-32 82 443 "CLK4,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,VAT1L,AQP6,LDHD,RUNX1T1,CLDN10,L3MBTL4,COPB2,RAB33A,CNR1,NCOR1,SNCAIP,PDE4DIP,DOCK4,HDAC4,BRINP1,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,SLC37A3,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,PADI2,ZNF546,GPR62,KCNJ16,KCNN3,PAXBP1,MEIS2,LAYN,NME4,WBP1L,CNTLN,RGS3,RGS4,CSRNP3,WDR37,ATF7IP,TET1,ZSWIM8,KDM4C,LMO3,VPS13A,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,FAM13C,RNF146,FAM198A,SPATA13" MicroRNA hsa-miR-194-5p:TargetScan hsa-miR-194-5p TargetScan 4.75E-34 2.66E-30 1.49E-33 1.37E-32 71 330 "ACHE,C3orf14,NDRG3,PITPNM2,CASK,MYRF,CAMK2G,CDH2,CFL2,QKI,BAG4,MYRIP,NSL1,CNTNAP2,PLCXD3,ARHGAP24,MATR3,ELMSAN1,DMD,HS3ST2,DUSP9,EDIL3,MBNL2,PLXNC1,EIF4G2,PAN3,ERBB4,ANKFY1,ATP6V1H,PPARGC1A,KDM2B,FERMT2,IL6ST,ITPKB,KCND2,LSAMP,MAP2,MEF2C,MEIS2,KITLG,MITF,AFF1,ADAM22,MYO5A,MYO9A,PDE4D,GNG2,PPP2R2C,PTPRD,ENOX1,KHDRBS2,REV3L,GTDC1,RFX3,FBXW7,SALL1,SATB1,HSPA4L,CHD9,BTBD7,IFT122,LIMCH1,FNBP1,CLASP1,NSD1,NACC2,CBX5,FLRT2,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-920:mirSVR_highEffct hsa-miR-920:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.15E-34 2.88E-30 1.61E-33 1.48E-32 92 557 "CCDC85A,ADD2,ADGRF5,CHID1,CFLAR,ARHGEF25,CBR1,LETMD1,SLC35F1,CREM,HINFP,SEC24C,RUBCN,CCDC144A,HDAC9,PITPNC1,B3GAT3,RHOBTB1,WDR20,CHRDL1,SEZ6L2,TMEM35A,C8orf37,EIF1,SRRM1,ZMYND15,FOLR2,HVCN1,CGREF1,DISC1,PLCD4,GUCY1B1,ZNF678,KCNK3,STXBP5,NCOA7,ASPRV1,MATN3,CHIC1,CNOT4,NUCB2,PDE3A,PDE4B,PDE4D,ZNF655,FAM216A,MTRF1L,PPP2R2B,C1orf109,RGS4,RNASEL,NEK11,ADAL,DGLUCY,PEAR1,COPZ1,FERMT1,BTBD3,TET1,GKAP1,SMARCD3,NMNAT2,TSPYL2,SPART,LARP4,ADHFE1,DMXL2,SZT2,SLC19A3,HIF3A,AP4E1,THRA,MTMR14,ACTR6,TPM1,C9orf85,ZNF346,METTL3,UBE3A,GORASP1,CLDND1,INTS3,GAL3ST3,SLC17A7,FIP1L1,WNK3,EPM2A,DOCK8,ST7,KAT6A,IFT88,NETO2" MicroRNA hsa-miR-2114:mirSVR_highEffct hsa-miR-2114:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.34E-34 2.99E-30 1.67E-33 1.54E-32 90 534 "NDRG3,ADD1,PWWP2A,RTL9,OGT,STK33,ZSCAN18,BID,GPC2,KALRN,CERS5,CFL2,PPT2,CNRIP1,SNCAIP,ARHGEF10,SOCS5,CYBB,HDAC9,ARHGAP32,DCAF8,CENPL,DBI,SEMA3D,PHF20L1,EPB41L2,POLR1B,FGF11,ANKFY1,PDLIM5,NSG1,OGA,MEGF10,GALNT15,DISC1,SESN1,PPARGC1A,GRB10,HSF2,SOWAHA,IL6ST,ZNF678,STXBP5,CAMK2N2,STMN1,NCOA7,LSS,ZFYVE27,MBNL1,MEF2C,AFDN,MXI1,SFR1,NINJ2,OCRL,GPR85,CEP41,HYDIN,SAMD9,C1orf109,RAP1GDS1,GTDC1,RIC8B,ROBO2,YY1AP1,RMI1,FERMT1,FAM81A,ATF7IP,SMARCC2,MPRIP,NEK4,RGL1,ANKRD28,C12orf76,MCF2L,ZEB1,TRIM2,PCDHB6,ARHGAP9,AP4E1,ELP5,SSBP2,RPL7L1,UCHL1,KCNT2,ZNF154,SPIRE1,VPS35L,MPPE1" MicroRNA hsa-miR-340*:mirSVR_lowEffct hsa-miR-340*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.40E-34 3.02E-30 1.69E-33 1.55E-32 112 806 "AS3MT,PLEKHH1,ADORA1,TAOK1,ZNF687,AMPD2,FGD2,PKP4,APAF1,KCNAB2,DDO,PHYHD1,PPFIA3,CDC14B,NUMB,DPY19L3,CARMIL3,KSR1,CALB2,SPAG9,CBS,KYAT1,METTL6,FBXO7,CSF1,VAC14-AS1,PHACTR3,GREB1,PUM1,DCAF4,ZFYVE16,LIN54,KIF19,SLC29A4,DOCK2,TOM1,DNAJB6,PHC2,RASA4,AASS,EPB41,VPS26C,ABCA8,MEX3B,CINP,USP21,ERGIC3,IP6K3,SYT17,GHR,TXNL4A,LUZP2,GNG4,DIDO1,CLASRP,ZBTB49,RABL2A,CPT1C,CELF5,ZNF678,STMN1,NCOA7,MAP4,MIA2,AFDN,SLC11A2,ZNF713,PTPRE,PEX2,CCDC40,ZNF493,GTDC1,RGS12,DCUN1D2,ALG9,EPHA10,ZNF568,STX1B,ZNF331,S100B,LRFN5,DHX30,SLC6A8,ZNF430,SNRPN,FNBP1,CDK19,ZBTB43,MCF2L2,ZSCAN29,SEPT8,NECAB1,ADAMTS17,CAMTA1,PDLIM2,IQCE,TNS2,HIF3A,ERCC6L2,RGMB,ZNF346,TSN,KLC2,XRCC4,POLR3H,UPF3A,SEMA3B,SIGLEC10,FIP1L1,CASC15,ADAMTS10,SPATA13" MicroRNA hsa-miR-422a:mirSVR_highEffct hsa-miR-422a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.78E-34 3.80E-30 2.12E-33 1.95E-32 112 808 "KCNH8,ADRB2,ARHGAP20,FAM135A,OGT,DDO,EIF4G3,ZNF599,CFLAR,IL33,CALB2,SLC25A14,TIGD7,PPT2,C4orf33,LY86,AKAP7,AHCTF1,TOGARAM2,ZFP28,CDC42BPB,CREM,ARHGEF10,ERC2,PHF14,USP6NL,CCDC144A,RIPOR2,DCAF8,DDX46,GRIN3A,DOCK2,EBF1,WDPCP,HIPK3,CELSR3,KMT5B,ENPP6,SPEG,FCGR1A,CEP78,FCGR3A,FGF12,TMEM164,ATP5PD,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRG2,ERAP1,DISC1,CBX1,GPT2,TDRKH,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,SMAP1,MYLK2,IL6ST,KIF2A,MARK1,MYCN,LYRM9,NCAM2,NDP,NEK1,NF1,NFE2L2,CHAMP1,LOC100128398,TRHDE,SCHIP1,PRKACB,PRPSAP2,APTX,SNRK,USP47,FIGN,RGS4,ELP2,FBXW7,BAALC,KIAA0895L,KCNIP1,ATF7IP,MBD5,IQSEC2,NXT2,NEK4,PLCB1,CAMTA1,AGTPBP1,DMXL2,FRYL,ZFPM2,AP4E1,PPIL6,GUSBP1,EML6,ZNF189,UPF3A,SLC30A4,CADM2,PRTFDC1,EPM2A,ST7" MicroRNA hsa-miR-6808-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.20E-34 4.03E-30 2.25E-33 2.07E-32 101 668 "ABCF1,AS3MT,NDRG3,RNF157,ADD2,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,ZNF555,PTBP2,ISPD,SLC16A4,CFL2,NRXN3,LETMD1,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,TMEM170A,ELMSAN1,SGSM2,SLC29A4,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,B4GALNT1,SESN1,GLUL,STARD3,ZNF638,FERMT2,ZNF496,BVES,IRAK3,AGBL5,ZNF546,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,SH3BP2,MYO18A,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,ZC3H4,FAM208A,USP22,PCDHA6,ARL10,ERCC6L2,SSBP2,USP1,BCL2L13,ZNF708,MPPE1" MicroRNA hsa-miR-877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.33E-34 4.10E-30 2.29E-33 2.11E-32 96 607 "ABR,EMILIN3,AP2A2,ZNF687,ANK2,TNRC6C,ARHGDIA,STK33,ZBTB10,CCAR2,AP1M1,SPAG9,RUNX1T1,SCARB1,ARHGEF2,LRRFIP1,DIS3L,COPB2,CLTC,IGLON5,SH2B1,AKAP12,RGS6,APPL1,TCAF1,DCAF8,KIAA0586,IP6K1,DBN1,SPATA2,RUSC2,POM121,RCAN1,ECM2,EPB41,SLC43A2,REEP2,TBC1D16,TUBA1B,SCML2,DLC1,SYNCRIP,ANKFY1,NELFCD,HHIPL1,RAPGEF6,SRCAP,ARFIP1,TCERG1,GLYR1,GLUL,ZNF638,CBX1,HTATSF1,PRRC2B,GPD2,GRM8,IPO5,CYP27C1,MBNL1,NACA,GNG2,OLA1,PKM,KCTD15,FAM216A,POLG,PRKCB,PIGG,EML5,PBRM1,SETD5,SBF1,SCAF8,ZFP30,MYO18A,FNDC3A,KANSL3,SLC6A8,LIMCH1,ZHX3,ERBIN,PRRC2C,TP53BP2,TTC3,HIRA,RPL7L1,BCL2L13,ZBTB38,AMZ1,SLC38A1,TUBA1A,FIP1L1,ITM2C,KAT6A,NHSL1" MicroRNA "CACTGCC,MIR-449:MSigDB" "CACTGCC,MIR-449:MSigDB" MSigDB 9.17E-34 5.13E-30 2.86E-33 2.63E-32 64 267 "ABR,TMCC3,ALCAM,ANK2,PKP4,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,TMEM184B,AKAP6,MYRIP,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,CPLX2,NTNG2,LOXL3,ATXN2L,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,GPR85,SEMA5B,STRN3,PKIA,EML5,TMEM255A,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,CAMTA1,SATB2,TCF12,MGAT5B,PLPPR2,NAV3,NETO1" MicroRNA "CACTGCC,MIR-34C:MSigDB" "CACTGCC,MIR-34C:MSigDB" MSigDB 9.17E-34 5.13E-30 2.86E-33 2.63E-32 64 267 "ABR,TMCC3,ALCAM,ANK2,PKP4,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,TMEM184B,AKAP6,MYRIP,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,CPLX2,NTNG2,LOXL3,ATXN2L,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,GPR85,SEMA5B,STRN3,PKIA,EML5,TMEM255A,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,CAMTA1,SATB2,TCF12,MGAT5B,PLPPR2,NAV3,NETO1" MicroRNA "CACTGCC,MIR-34A:MSigDB" "CACTGCC,MIR-34A:MSigDB" MSigDB 9.17E-34 5.13E-30 2.86E-33 2.63E-32 64 267 "ABR,TMCC3,ALCAM,ANK2,PKP4,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,TMEM184B,AKAP6,MYRIP,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,CPLX2,NTNG2,LOXL3,ATXN2L,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,GPR85,SEMA5B,STRN3,PKIA,EML5,TMEM255A,FIGN,RIC8B,ZFHX4,SATB1,SCN2B,CPEB3,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,CAMTA1,SATB2,TCF12,MGAT5B,PLPPR2,NAV3,NETO1" MicroRNA hsa-miR-938:mirSVR_highEffct hsa-miR-938:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.35E-34 5.23E-30 2.91E-33 2.68E-32 80 426 "AS3MT,FMNL2,ADD2,KLHL13,ADGRF5,AMPD3,APAF1,PLA2G4C,MPDZ,SEC11C,SLC25A14,DGKI,MAGI1,SRSF11,RAB28,MYRIP,CPS1,SEC31B,SNCAIP,PDE4DIP,DOCK4,HDAC9,ARHGAP32,ARMCX4,SACS,NR1D2,GOLT1B,FSD1L,ING4,TAOK3,FHL1,POLK,MEX3B,NOP56,STAMBP,STAU2,RAB30,ZNF496,RNF165,FRMD3,ZDHHC15,SMAP1,IRF8,IL12A,MARK1,MMP16,SFR1,NEK1,VPS13C,MTMR10,ZSCAN32,ERI2,FBXW7,FAM192A,ATXN2,ATXN7,FHOD3,ARHGEF40,CPEB4,RCOR3,MCF2L2,SEPT3,ANKRD12,ADGRL3,SIN3B,ZFP90,SLC19A3,SIK3,TIAM1,NR2E1,TRIO,FAM155A,WIPF1,SMARCAD1,PRDM8,RGS7BP,HNRNPA3,PHTF2,FAM219B,MSRB3" MicroRNA hsa-miR-139-5p:TargetScan hsa-miR-139-5p TargetScan 1.20E-33 6.71E-30 3.73E-33 3.44E-32 69 315 "NDRG2,GALNT13,KCTD16,PCDH10,LRCH2,ANK2,ATP2B2,SCAPER,MTMR2,CACNA2D1,CBFA2T2,CACNA2D2,QKI,JAKMIP2,DMD,DPP6,EBF1,PLXNC1,EIF4G2,EIF1,MRVI1,MEX3B,FAM49B,GABRA3,PPARGC1A,GLI2,GNAL,GPR37,MIER3,ELOVL5,HMGCR,NEGR1,CDH20,KCNB1,KLHL23,KTN1,LSAMP,MAP2,MBD1,MBNL1,MEIS2,NPTX1,PCDH9,PCSK5,PDE3A,PDE4A,PDE4D,KCTD15,PMP22,LRP12,SCHIP1,LRRN3,RASGEF1B,PTPRD,RASGRF1,RORB,CSRNP3,LRFN5,ARX,CHD9,KIF13A,ASXL3,KAT6B,KLC2,NDRG4,DPYSL5,PRDM10,FZD3,KAT6A" MicroRNA hsa-miR-762:mirSVR_highEffct hsa-miR-762:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-33 6.72E-30 3.74E-33 3.44E-32 101 672 "ABCF1,CLK4,NDRG2,DPY19L2P4,OLMALINC,SPOP,ARHGAP20,PKP4,TNRC6C,PPFIA3,ARNTL,CCDC74A,SLC2A11,DPY19L3,SYNJ1,KALRN,PTBP2,RUNX1T1,P2RX6,ARHGEF2,PLEKHB1,ZNF385A,CPS1,SH2B1,NCOR1,CLIP3,SEC24C,UBXN2A,PUM1,GIT2,EXOG,FCF1,EGFR,EPB41L2,CLVS1,ZNF589,SLC9B2,PRKAG2,USP21,CAMKK2,DISC1,KIAA1841,GCK,GGT7,GLYR1,LOXL3,GNAO1,TDRKH,CLASRP,TOX2,ARHGAP36,HMGCL,SMAP1,IL6ST,INPP5B,IPO5,HECTD2,MEIS1,MYO7A,ZNF655,POLR2F,PPP2R5E,WBP1L,TMEM104,PTPRD,RASGRF1,EXD2,CARF,YY1AP1,MAP6D1,KCNIP1,FAM192A,ARHGEF40,SIRT2,SP4,ERC1,SPTAN1,IQSEC2,NFASC,ATP10B,ST5,MPRIP,STAC2,ADHFE1,ZFP90,TRIM2,NAT16,MTMR14,HEY1,PIK3R5,ZNF346,HSPBP1,UGT8,OSBP2,BCL2L13,MTCH1,CLDND1,CFAP298,TMEM178A,ADAMTSL3,JPH3" MicroRNA hsa-miR-224:PITA hsa-miR-224:PITA_TOP PITA 1.63E-33 9.13E-30 5.07E-33 4.67E-32 72 346 "TMEM132B,APBA2,USP37,RASL11B,SLC4A4,CAST,C1orf52,CCPG1,FOXN3,CHN1,QKI,MAP4K4,PCYT1B,IGDCC3,USP6NL,FBXL5,WDR20,DNM1,USP3,CPEB2,DPYSL2,MAMLD1,EDNRA,HIPK3,FRY,MBNL2,KATNAL1,ACSL4,FGF14,AMOTL2,SUCO,FAM49B,TCERG1,SPIN1,TNRC6A,CIT,HMGCR,AGFG1,STMN1,MBNL1,MID1,HS6ST3,MYO5A,NF1,CNTN3,PFKFB3,PIK3C2A,SH3KBP1,RELN,WBP1L,PTX3,OXR1,RADX,ZFHX4,CARF,CASC3,TRA2B,CHD9,SOX11,KDM3A,ZNF423,POGZ,NKAIN2,SEPT3,ARHGEF9,PUM2,FRYL,FAM155A,SMARCAD1,RTN4,KAT6A,ZDHHC20" MicroRNA hsa-miR-129-3p:mirSVR_highEffct hsa-miR-129-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-33 9.19E-30 5.11E-33 4.70E-32 89 530 "ACADM,XKR4,NDRG2,FMNL2,KLHL13,HFM1,NAE1,BTK,JAZF1,PTBP2,USP6,DGKI,HECTD1,COL9A1,LETMD1,ABI3BP,COX4I1,RBM39,VAC14-AS1,DOCK4,SPATA2,RHOBTB1,SACS,GOLT1B,E2F5,PHF20L1,RCAN2,F5,ZSCAN30,MED12L,POLK,NOP56,AKAP3,DISC1,GRIK4,GRIN2D,PRDM5,FRMD3,FAM69A,KHK,KIF5A,PAXBP1,HECTD2,PIK3AP1,MMP16,MYO9A,NINJ2,GPR137C,GLIPR1L2,TRHDE,PKIA,GDPD2,MTMR10,SPDL1,ERI2,RFX3,RGS12,SUGCT,CCDC102B,BAALC,TCP11L1,MEG3,RYR3,NCBP3,CASC3,FRMPD1,ABLIM3,DHX30,SLC9A5,BDP1,ATP10B,CLASP2,SS18,ERBIN,ANKRD12,SLC19A3,FRYL,PMS2CL,TIAM1,HEY1,TRIO,TRO,RPL7L1,FAM155A,FLRT2,PRDM8,PLSCR4,PHTF2,LAS1L" MicroRNA hsa-miR-940:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-33 1.01E-29 5.61E-33 5.17E-32 104 713 "ABCF1,AS3MT,NDRG3,RNF157,ADD2,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,ZNF555,PTBP2,ISPD,SLC16A4,CFL2,NRXN3,LETMD1,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,TMEM170A,ELMSAN1,SGSM2,SLC29A4,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,B4GALNT1,RAPGEF6,SESN1,GLUL,STARD3,ZNF638,FERMT2,ZNF496,BVES,IRAK3,AGBL5,ZNF546,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,KSR2,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,SH3BP2,MYO18A,SHMT2,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,ZC3H4,FAM208A,USP22,PCDHA6,ARL10,ERCC6L2,SSBP2,USP1,ZNF708,ZNF24,MPPE1" MicroRNA "AGCACTT,MIR-526B:MSigDB" "AGCACTT,MIR-526B:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520D:MSigDB" "AGCACTT,MIR-520D:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520C:MSigDB" "AGCACTT,MIR-520C:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302A:MSigDB" "AGCACTT,MIR-302A:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520A:MSigDB" "AGCACTT,MIR-520A:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-93:MSigDB" "AGCACTT,MIR-93:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-372:MSigDB" "AGCACTT,MIR-372:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-373:MSigDB" "AGCACTT,MIR-373:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302B:MSigDB" "AGCACTT,MIR-302B:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520E:MSigDB" "AGCACTT,MIR-520E:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520B:MSigDB" "AGCACTT,MIR-520B:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302D:MSigDB" "AGCACTT,MIR-302D:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302C:MSigDB" "AGCACTT,MIR-302C:MSigDB" MSigDB 1.83E-33 1.02E-29 5.63E-33 5.18E-32 69 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,ZNF385A,C2CD2,ARHGEF10,HDAC4,RASSF2,MAML1,IP6K1,MFAP3L,KLHL3,DMTF1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,HLF,NCOA7,MEF2C,MYCN,NFYA,KANSL1,MAPK9,OXR1,RIC8B,FBXO11,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,NR2C2,TRPS1,VLDLR,DPYSL5,EMSY,PRDM8,NELFE,FAM13C,MARCH8,FAM219B,ST8SIA2" MicroRNA hsa-miR-6893-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-33 1.35E-29 7.41E-33 6.82E-32 100 665 "ABCF1,AS3MT,NDRG3,RNF157,ADD2,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,ZNF555,PTBP2,ISPD,SLC16A4,CFL2,NRXN3,LETMD1,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,TMEM170A,ELMSAN1,SGSM2,SLC29A4,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,B4GALNT1,SESN1,GLUL,STARD3,ZNF638,FERMT2,ZNF496,BVES,IRAK3,AGBL5,ZNF546,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,SH3BP2,MYO18A,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,ZC3H4,FAM208A,USP22,PCDHA6,ARL10,ERCC6L2,SSBP2,USP1,ZNF708,MPPE1" MicroRNA hsa-miR-1287:mirSVR_highEffct hsa-miR-1287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-33 1.38E-29 7.57E-33 6.97E-32 107 754 "EMILIN3,XKR4,HECW2,UNC79,TNRC6C,SPTBN4,CDK13,ZNF583,SEC11C,CFLAR,CA8,SPAG9,METTL6,LRBA,ARHGAP33,CHN1,PPT2,QKI,SUMF2,CREM,ANKRD44,GDA,GREB1,RIMS2,KIAA0408,TCAF1,TMEM170A,ELMO1,RAB39B,DTNA,ANKRD46,EGFR,TMEM35A,STARD3NL,CALCRL,RCAN2,LRRC17,CDKL3,FKTN,ZNF589,SLC9B2,FER,NOP56,NELFCD,SPECC1,AP4B1,OGA,ZNF44,SULT1C4,MALT1,COPS8,KDM2B,MCHR1,ADAMTS13,PSIP1,FRMD3,ITPKB,SLC35G1,KCNB1,LIG4,AQP11,CNOT4,P2RX7,PDCD2,GNG2,DUSP26,MTRF1L,PMP22,EXOSC10,EPDR1,MASP1,ZIK1,PID1,RAP1GDS1,RIC8B,ZFHX4,CARF,RPS20,ABCA11P,S100B,DGLUCY,CASC3,SH3GL3,FERMT1,FBXO11,CXXC4,SOX15,ERC1,ATMIN,SATB2,TCF12,USP32P1,AP4E1,TLR4,ERCC6L2,R3HDM1,CHST5,VLDLR,KCNT2,EMSY,NAV3,PDSS2,EPM2A,RGS7BP,AMN1,KAT6A,CASC15" MicroRNA hsa-miR-1224-3p:mirSVR_highEffct hsa-miR-1224-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-33 1.44E-29 7.92E-33 7.30E-32 84 476 "NCKAP5,NDRG2,CCDC85A,BRAP,PDZD4,CDC42BPA,UPRT,VAT1L,ADAM23,SYNJ2,PTBP2,CAMK2G,CD86,PLEKHB1,DGCR9,HECTD1,MYRIP,SEC24C,SIPA1L1,ZFYVE16,ZNF337,TBC1D5,SPOCK2,RUSC2,HS3ST2,DMTF1,EPB41,ZNF391,SPEG,PRMT5,SUCO,ANKFY1,TMEM107,ST6GALNAC3,GABRA3,TRAF3IP2,SULT1C4,MSL3,TDRKH,CLASRP,ADAMTS6,USP51,LRRC75A,IL6ST,IL12A,ITGA7,KCNN3,KIF5A,L1CAM,CAMK2N2,MIA2,ZNF92,GLIPR1L2,PLCL1,SEPT4,CCDC144B,PRKACB,GRAMD1C,BDNF-AS,STRC,RGS12,TMLHE,ELP2,ABCA11P,FNIP1,TNFRSF19,FOXRED1,SMARCC2,DBNDD2,RBM26,LARP4,TTBK2,ADHFE1,NSFL1C,SYNE2,PLCB1,CAMTA1,NAT16,SLC35A4,ZNF708,TRIM9,LYPD6,VPS35L,ZNF30" MicroRNA hsa-miR-1266:mirSVR_highEffct hsa-miR-1266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.83E-33 1.58E-29 8.70E-33 8.01E-32 96 617 "ADD2,BRAP,PTCHD1,AK2,GPRASP2,EPB41L5,BCAS1,CADPS,INSYN2B,EIF4G3,ATP6V0A1,NRP2,PTBP2,CBS,CLTC,ARMC8,NCOR1,CLIP3,CS,DCAF8,MATR3,DAPK1,PITPNC1,DTNA,FIS1,SNX29,EDN1,RASA4,IRAK4,EPHB1,ANKMY1,CLVS1,NSRP1,PRMT5,FER,FGF11,IP6K2,NOP56,NELFCD,SMC2,MSANTD4,ZNF44,ADGRA3,PSIP1,NKD1,KIT,ZFYVE27,MARK3,MBNL1,KCTD6,MSI1,MYO7A,NINJ2,ETFRF1,PDCD2,PDE1C,NALCN,EPB41L4B,APTX,CNTLN,TMEM260,NKAIN1,SLC25A48,MSANTD2,SLC25A36,ZFHX4,ARMC5,GSTCD,NEK11,TCP11L1,MYO18A,SHMT2,PPP4R3A,FAM214B,ARHGEF40,TSNAXIP1,HECW1,MPRIP,VPS13A,ANKRD28,TIAM1,NACC2,ERCC6L2,NPL,SYNPO2,TRIO,TSN,TTC3,WIPF1,P2RY12,GUSBP1,PCDH20,ZNF189,ANKS1B,UPF3A,LAS1L" MicroRNA "CATTTCA,MIR-203:MSigDB" "CATTTCA,MIR-203:MSigDB" MSigDB 3.88E-33 2.17E-29 1.19E-32 1.10E-31 63 264 "NDRG3,FMNL2,ZNF608,PCDH19,OSBPL8,MAP4K3,PHF12,APC,ARNTL,SLC4A4,STX16,ATP2B2,BCL7A,SYNJ1,CAPN3,ZMYM4,MAGI1,NUMBL,SOCS6,PLAA,CNTFR,DGKB,MYEF2,EDN1,MBNL2,EGR3,ETV1,NBEA,GABRB3,LRRC37A6P,GNAO1,ADAMTS6,NEGR1,LAMP2,SMAD1,MBNL1,MEF2C,NOVA1,PCSK1,PDE4D,GPR85,PPM1B,PRKCB,MAPK9,PTPRG,ZNF532,SLC12A2,BTBD7,CPEB4,LIMCH1,SP4,NMNAT2,CLASP2,SEPT3,KIAA0930,RPGRIP1L,TCF12,GALNT17,R3HDM1,NR2C2,TRPS1,SGK3,SPIRE1" MicroRNA hsa-miR-3117:mirSVR_highEffct hsa-miR-3117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.08E-33 2.28E-29 1.25E-32 1.16E-31 97 632 "KCNH8,ADD1,ADRB2,SPOP,FAM135A,TMEFF1,NRP2,DST,RUNX1T1,ASIC3,LHX2,CLCN3,ARMC8,SUMF2,COL9A1,SLC4A8,ABI3BP,RNF14,VCAN,SLITRK5,PHF14,GREB1,GPRASP1,EARS2,MAML1,ARMCX4,EXOG,DYNC1I1,DPH1,PDCD6IP,RGS17,DENND4A,CLVS1,FDFT1,GORAB,FGF12,ANKFY1,AP4B1,IP6K3,DISC1,SULT1C4,STARD3,ZNF638,LUZP2,GPT2,LNX1,GSTT2,IRAK3,NEGR1,TCEAL6,LIMS1,HECTD2,NCOA7,ZNF680,NCAM2,NF1,PDE1C,PSAT1,PIGG,TMEM260,QDPR,RAP1GDS1,RASGRF1,CARF,ABCA11P,SEMA6D,SATB1,CSRNP3,ZFP2,KIF21A,SHC4,ATF7IP,CPEB4,RCOR3,BDP1,KDM4C,NKAIN2,PLCB1,MMS19,ATMIN,TCF4,CLASP1,SLC44A1,TIAM1,ERCC6L2,TMPO,PDSS1,AMACR,OSBP2,BCL2L13,ZNF74,ZNF189,DHX33,PPP1R3F,HNRNPA3,NHSL1,SENP7" MicroRNA hsa-miR-615-3p:Functional MTI Functional MTI miRTarbase 4.94E-33 2.76E-29 1.52E-32 1.40E-31 117 893 "ABCF1,ACTN1,PWWP2A,ZNF687,SEMA7A,EP400,APBA2,ARRB2,CCAR2,DST,FUBP1,CBS,SCARB1,ENTPD6,LRBA,LONRF2,CDH2,ARHGAP22,CLTC,MAGED1,NCOR1,SEC24C,GPSM1,ZFYVE16,MATR3,INTS1,DBN1,FAM107B,SEC16A,DNM1,DNM1L,FAM13A,ASB3,EIF4G1,MTSS1L,EZH1,TUBA1B,CHST15,SCARA3,FOXO3,APOPT1,PRELID3A,SARAF,SRCAP,USP19,TCERG1,RNPS1,GLUL,PRRC2B,DIDO1,CACFD1,BVES,BACH2,MIER3,HMGCR,CPT1C,IDH3B,IL6ST,ITGA7,KIF2A,ZFYVE27,MBD1,AFF1,MOV10,MPP2,MXI1,MYO9A,NACA,HNRNPM,NPTX1,NTRK3,CHAMP1,OGG1,PKD1,PLEC,SMOX,LRP12,MBOAT7,POLG,PPP5C,PRKAB2,EPDR1,WBP1L,RAD51D,RFX3,KLHL11,KIRREL1,RPL15,SUPT20H,SHMT2,EPN2,SEPHS1,RADIL,SMARCA4,SMARCC2,KDM4B,FNBP1,NMNAT2,RHBDL3,DNAJC9,SYPL1,TAF6,EXOC7,NSD1,PUM2,AKTIP,TIAM1,TMPO,BEX4,CDK20,NR2C2,UBC,RPL7L1,ZNF711,POLR3H,TUBA1A,SOCS4" MicroRNA hsa-miR-6499-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.84E-33 3.27E-29 1.79E-32 1.65E-31 116 881 "ABCF1,CLK4,XKR4,NDRG3,ELFN2,ESYT2,SLC24A4,HECW2,HACE1,TXNDC16,ZNF578,AQP6,SFMBT2,ASPA,STX16,DOCK11,ST3GAL5,PTBP2,CBS,CBFA2T2,EVI5L,CDR1,CCPG1,NRXN3,PLAA,TPP1,OSBPL3,MYADM,GAPVD1,TMEM170A,IP6K1,DNAL1,DBT,YTHDC1,GUCD1,MTX3,DMD,DNAH9,KRBA2,FEM1B,HEYL,OPTN,MRO,RASA4,MRNIP,TUBD1,COQ7,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,SEC23B,SPECC1,MSANTD4,TRAF3IP2,DISC1,CRCP,GNG4,LILRA2,KAT7,IGF1,IBA57,LIMS1,GPR155,MAT2A,MKLN1,MXI1,OPRL1,OLA1,ZNF655,CCSER2,GPSM2,PLCD1,TATDN3,FITM2,MTMR10,PEX2,CEP97,RBBP8,TRIM68,ALG9,PGBD4,SNX22,PTGR2,NCBP3,FNIP1,HSPA4L,SHC4,BTBD3,ATF7IP,ANKRD36,FNBP1,ERC1,LHPP,ZNF621,ZSCAN29,KLHL7,ALG1,SATB2,USP22,ZNF106,THRA,BHLHB9,PPIL6,SSBP2,USP1,LAT2,AGMO,ZNF74,ZNF154,EVI5,TIGD6,RNF170" MicroRNA hsa-miR-509-3-5p:PITA hsa-miR-509-3-5p:PITA_TOP PITA 6.29E-33 3.52E-29 1.93E-32 1.78E-31 66 294 "TAOK1,ZNF687,AMPD2,MAP4K3,CDC14B,NUMB,CAMK2G,RUNX1T1,ZNF501,DCLK1,SRSF11,QKI,AKAP6,COL4A5,ZNF521,MAML1,DPYSL2,YAF2,TENM1,EPB41,OLFM1,GALC,MSTN,GHR,TNRC6A,MSL3,CIT,ZHX1,BACH2,MIER3,AGFG1,KCND2,MBNL1,MEIS1,MN1,ZC3H12B,GPR137C,GPR85,CCSER2,RETREG1,LRRN3,KANSL1,BCAS3,TMEM260,RIPOR1,USP47,FIGN,ZFHX4,SETD5,RYR3,SCAF8,NLGN1,TET1,RCOR3,FAM126B,SOX11,ZNF423,CAMTA1,FBXW11,TRIM2,RPGRIP1L,ZFAND5,SLC30A4,WNK3,PDSS2,HNRNPA3" MicroRNA hsa-miR-509-5p:PITA hsa-miR-509-5p:PITA_TOP PITA 6.29E-33 3.52E-29 1.93E-32 1.78E-31 66 294 "TAOK1,ZNF687,AMPD2,MAP4K3,CDC14B,NUMB,CAMK2G,RUNX1T1,ZNF501,DCLK1,SRSF11,QKI,AKAP6,COL4A5,ZNF521,MAML1,DPYSL2,YAF2,TENM1,EPB41,OLFM1,GALC,MSTN,GHR,TNRC6A,MSL3,CIT,ZHX1,BACH2,MIER3,AGFG1,KCND2,MBNL1,MEIS1,MN1,ZC3H12B,GPR137C,GPR85,CCSER2,RETREG1,LRRN3,KANSL1,BCAS3,TMEM260,RIPOR1,USP47,FIGN,ZFHX4,SETD5,RYR3,SCAF8,NLGN1,TET1,RCOR3,FAM126B,SOX11,ZNF423,CAMTA1,FBXW11,TRIM2,RPGRIP1L,ZFAND5,SLC30A4,WNK3,PDSS2,HNRNPA3" MicroRNA hsa-miR-3160:mirSVR_highEffct hsa-miR-3160:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.31E-33 3.53E-29 1.93E-32 1.78E-31 118 909 "ACADM,ABHD6,PWWP2A,KIAA1211,HECW2,NME5,OGT,PDE8B,BCS1L,BLM,SGCE,CACNA1G,KALRN,ARHGEF25,CFL2,QKI,HECTD1,NCOR1,CS,PHACTR3,RIMS2,RUBCN,CCDC144A,GPRASP1,GIT2,TMEM130,LYPD1,GRIN3A,DMD,DPP6,ECM2,DNAJB6,ABCC5,DNM1L,EDIL3,SEMA3D,GOLGA7,PAN3,FCGR3A,FDFT1,FGF11,SEMA4D,CGREF1,IP6K3,ERAP1,DISC1,INPP5K,ADAM28,LYVE1,GNG4,GPD2,DIDO1,ADAMTS6,GUCY1B1,ZNF546,C2orf72,INPP5B,KCNH2,KCNJ16,IPO5,MAT2A,TM6SF1,XRRA1,MSR1,NFE2L2,DNHD1,SLC11A2,OCRL,OXTR,ZNF827,PCDH9,PDE4D,ZNF655,PRIMPOL,POLR2F,PRKAB2,CNNM2,WDR25,PTPRG,MARCH1,TMEM255A,RFX2,NUDT11,CARF,SNX22,NEK11,RPL15,ATXN2,ATXN7,SLA,PEX26,DHX30,INTS9,TTC17,KDM3A,ATP10B,POGZ,TTBK2,VPS13A,DNAJC9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,SIRT1,ITGB3BP,AP4E1,RASD2,RPL7L1,ZNF540,ANKS1B,RNF103,PDSS2,CASC15" MicroRNA hsa-miR-513b:PITA hsa-miR-513b:PITA_TOP PITA 6.32E-33 3.54E-29 1.94E-32 1.78E-31 69 323 "FAM135A,APC,NCOA1,SYNJ1,C1orf52,CCPG1,NRXN3,PCYT1B,AKAP6,IGDCC3,CRMP1,CSNK1G3,FAM131B,GAPVD1,HDAC4,SPATA2,POM121,DLX1,GRIN3A,RASGRP2,ERBB4,EZH1,TAOK3,AFF2,OGA,GABRG1,ARFIP1,PCDH17,SPIN1,KAT7,NEGR1,INSM1,SLC35G1,MARK1,MAT2A,NEXMIF,GPR85,PDZRN4,MAPKAP1,PPP3CA,CEP41,SLC25A36,ZFHX4,PPP4R3A,CPEB4,TMCC1,DOK5,MYCBP2,PEG10,CDK19,STAU1,SYN2,CAMTA1,TAL1,TCF4,TRIM2,NSD1,CRTC1,SIRT1,KAT6B,SLC35A4,CLIP2,ZIC2,SMARCAD1,EMSY,CADM2,HNRNPA3,SOCS4,SENP7" MicroRNA hsa-miR-202:PITA hsa-miR-202:PITA_TOP PITA 6.44E-33 3.60E-29 1.97E-32 1.81E-31 58 222 "XKR4,CASKIN1,PCDH19,ZBTB10,BCL7A,SYNJ1,FOXN3,CHN2,NDST3,MYRIP,SEC24C,ZC3H11A,CPEB2,DRP2,DUSP9,SEMA3D,YAF2,TENM1,TMEM35A,STARD3NL,DLC1,IP6K2,GHR,PPARGC1A,TNRC6A,RNF165,HAS2,MIER3,NEGR1,SMAP1,KCNK3,KIF2A,MYCN,GPR137C,PMP22,TRHDE,LRRN3,LAMA1,PTPRD,PTPRO,CPEB3,DZIP1,WDR47,CPEB4,SOX11,HECW1,STAU1,SULF2,PRRC2C,SYN2,SYT1,TCF4,DICER1,CSMD1,SLC30A4,ADAMTS9,KAT6A,PHTF2" MicroRNA hsa-miR-1293:mirSVR_highEffct hsa-miR-1293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.77E-33 3.79E-29 2.07E-32 1.91E-31 88 528 "OLMALINC,SLC24A4,RTL9,ZFAT,LGR5,ARRB1,N4BP2L1,TTLL9,DST,BTK,CACNA1B,SRSF11,NRXN3,SRP14-AS1,CNR1,CCDC144A,KIAA0586,DGKG,PITPNC1,GSDME,TOM1,MBNL2,VPS13B,SRRM1,NRN1,F5,ZSCAN30,KAT8,POLR1B,WDR83,SMC2,NSG1,HRASLS5,DISC1,KIAA1841,TUBGCP4,TUBA8,USP19,GLUL,PRUNE2,ATE1,LIMS1,TM6SF1,MEIS1,MEIS2,GIT1,CNOT4,NLGN3,PLCL1,PRIMPOL,SH3KBP1,RANBP3L,SLC26A11,SLC25A48,RBBP6,GTDC1,ZFHX4,PNMA8A,GSTCD,ROBO1,ROBO2,MRAP2,ABCA11P,SEMA6D,FERMT1,ATF7IP,SMARCD3,SNRPN,PDZRN3,POGZ,ZSCAN29,ARHGEF9,COBL,MLST8,DMXL2,FAM200B,FAM124A,ELP5,TRO,MGAT5B,NPDC1,CELF4,ZNF225,DNALI1,PDSS2,FBXO36,IFT88,GAN" MicroRNA hsa-miR-1208:PITA hsa-miR-1208:PITA_TOP PITA 6.93E-33 3.88E-29 2.12E-32 1.95E-31 67 304 "PTCHD1,OSBPL8,ALCAM,FAM135A,OGT,FUBP1,CDH2,CACNA2D2,FOXN3,CHN1,HECTD1,MAP4K4,ARHGEF6,ARMC8,FAM171B,SOCS5,ERC2,PLCXD3,USP6NL,HDAC4,KCTD8,CHRDL1,GRIN3A,CPEB2,DPYSL2,ABCC5,FGF13,PCDH17,FRMD3,MIER3,ZNF546,KCND2,MEIS1,MXI1,GPR137C,GPR85,ANKRD16,STRN3,RELN,PTCH1,ZFHX4,ROBO2,SALL1,SEMA6D,TRA2B,FNDC3A,BTBD3,CCDC88A,CPEB4,SNAP25,MBD5,POGZ,ITPRID2,ARHGEF9,CAMTA1,MGRN1,CUX2,RIMBP2,UBE3A,LYPD6,TCEAL7,ZBTB38,CADM2,NAV3,HNRNPA3,FRMD6,ST8SIA2" MicroRNA hsa-miR-1303:PITA hsa-miR-1303:PITA_TOP PITA 1.02E-32 5.70E-29 3.11E-32 2.87E-31 62 259 "CH25H,LRBA,MAGI1,CHN1,TBPL1,CNTNAP2,ERC2,PUM1,SCRN1,ELMSAN1,ELMO1,APH1A,EGR3,FGF1,FGF11,FOXO3,GATM,TCERG1,ZHX1,MIER3,ZNF546,MATN3,MBD1,NDP,NOVA1,PCDH9,ENPP2,TRHDE,PPP2R5E,PPP3CA,PTCH1,PTPRD,CEP97,KHDRBS2,RDX,RIC8B,ZFHX4,SALL1,CSRNP3,SCN8A,PPM1E,WDR37,FAM81A,ZHX3,ARHGAP26,ITPRID2,LARP4,ZC3H4,PRRC2C,ANKRD28,FAM208A,TCF4,TCF12,AKTIP,R3HDM1,AMACR,FAM155A,TOM1L2,ZIC1,SMARCAD1,CADM2,SENP7" MicroRNA hsa-miR-155-5p:TargetScan hsa-miR-155-5p TargetScan 1.12E-32 6.26E-29 3.42E-32 3.15E-31 75 387 "HECW2,FAM135A,C6orf89,LCORL,APC,ARRB2,DOCK11,BACH1,KSR1,FUBP1,CACNA2D1,CACNB4,CBFA2T2,NGEF,QKI,LETMD1,CSF1R,PITPNM3,SEC14L5,CD99L2,DYNC1I1,DMTF1,EBF1,PHC2,KCTD3,C3orf18,ETV1,SCML2,MEX3B,FOXO3,FLT1,ANKFY1,FUT9,RAB30,PARD3B,MIER3,AGFG1,IL6R,IL6ST,METTL21A,PAXBP1,LRP1B,MEIS1,MMP16,NFIX,NFYA,NOVA1,PDE3A,PIK3R1,LRP12,KANSL1,CEP41,PKIA,PTPRD,RDX,RFX3,CYB561D1,SALL1,SATB1,CHD9,FBXO11,ANKRD6,BTBD3,CPEB4,MBD5,KDM3A,HECW1,NFASC,SATB2,DOK6,RICTOR,NAV3,PDSS2,HNRNPA3,FXR1" MicroRNA hsa-miR-18a*:mirSVR_highEffct hsa-miR-18a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-32 6.90E-29 3.77E-32 3.47E-31 100 678 "SYN3,NDRG2,ADD2,BRAP,FAM135A,DPP10,SEMA4G,ARNTL,MARK4,BACH1,NRP2,WASF1,CACNA2D1,LDB2,CHGB,SRP14-AS1,WHRN,SLC35F1,CPS1,HAPLN1,TRIM69,SNCAIP,ARHGEF10,CSNK1E,GREB1,ARHGAP32,IP6K1,SLC12A6,PHC2,PHF20L1,SUGP2,KMT5B,HSPA12B,ACSL4,FER,C2orf88,ATP2C1,ALDH1L1,BRD8,PRRC2B,RNF165,ZBTB49,AP4S1,RABL2A,SLC2A6,PADI2,SMAP1,CDH20,STXBP5,NCOA7,POC1B,AFF1,MYO9A,ZC3H12B,NF1,CNOT4,NOVA1,NTRK2,PLCB2,PURG,PPP1R1A,PKIA,HYDIN,MASP1,CNTLN,BDNF-AS,STK32A,PID1,CEP97,RDX,CCDC82,MRAP2,FBXW7,FAM192A,PPP4R3A,SLC6A11,SLC12A2,RCOR3,IFT122,MAPKBP1,NECAB1,NUDT10,SYP,ASTN2,USP32P1,GPR161,TMPO,RIMBP2,PIK3R5,ELP5,DCBLD1,KCNE5,FLRT2,CFAP298,UPF3A,PRDM8,PCBP4,WNK2,RNF170,MSRB3" MicroRNA hsa-miR-744:mirSVR_lowEffct hsa-miR-744:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-32 6.93E-29 3.78E-32 3.48E-31 104 729 "ASIC1,CLK4,PLEKHH1,UNC5A,ZNF608,CC2D2A,PITPNM2,AMPD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,APOC1,PPFIA3,SPTBN4,ARHGDIA,ARRB2,NUMB,SYNJ2,CASTOR3,DDR1,USP2,ARHGEF1,KCNAB3,ASIC3,TAOK2,IQCK,ARMC8,ZNF385A,C2CD2,C1QL2,AATK,IP6K1,PITPNC1,SGSM2,FAM107B,NYAP1,DPH1,DNM1L,TMEM132E,C3orf18,EZH1,FCGR1A,GTF2IRD2,AMOTL2,NOP56,FLYWCH1,INPP5K,ALDH1L1,GFRA2,LYVE1,GPER1,GRIN2D,AP4S1,LRRC75A,KCND1,LINC00634,MAN2A2,ADAM11,NPTX2,TBC1D25,ZNF827,ZDHHC8,FAM216A,FXYD1,PILRA,NKAIN4,PPP5C,PRKAB2,MASP1,BCAS3,TMEM260,CCDC40,IQSEC3,PRRT2,ARMC5,NEK11,GLDN,ATAT1,ATXN2,FAM81A,SLC6A8,MAST1,SOX3,SP2,CAMTA2,SYN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RELL2,PRRT1,ELP5,DCBLD1,RUSC1,CLEC2L,TOM1L2,KLC2,NT5M,DNALI1,URM1,WNK3" MicroRNA hsa-miR-760:mirSVR_highEffct hsa-miR-760:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-32 7.22E-29 3.93E-32 3.62E-31 101 691 "BRAP,DOC2A,LCORL,SUGT1P4-STRA6LP-CCDC180,SPTBN4,ARNTL,NUMB,SYNJ2,CACNA1I,CAST,CBR1,AP4M1,AKAP7,ARMC8,AKAP12,HINFP,GDA,SEC24C,VCAN,PUM1,DCAF4,KATNAL2,DGKB,DGKG,GIT2,ARMCX4,MYEF2,WDR20,HS3ST2,DNAH9,HIPK3,GOLGA7,TMEM35A,RAB9B,SRRM1,FCGR3A,FGF11,RGPD5,AKAP3,PDLIM5,GABBR1,GALC,DISC1,GDF9,LOXL3,BTN2A1,KAT7,HMGCR,SHISA6,KHK,KIF2A,KIF5A,MBNL1,MEIS2,MMP16,GIT1,MSR1,NF1,SLC11A2,GNG2,TMIE,PLIN1,TRHDE,SPDL1,MARCH1,SLC25A48,RBBP6,GTDC1,RGS3,RGS12,NUDT11,EPHA10,SPIN3,ATP8B4,KCNIP3,ATXN7,SGK1,SHMT2,ATF7IP,ZNF667,SMARCD3,RCOR3,TTC17,SNRPN,NMNAT2,HECW1,ZC3H13,SS18,SEPT8,PJA1,SYNE1,CYB561A3,AP4E1,SLC44A1,CDK20,WBP2,NDRG4,UPF3A,SEMA3B,FAM13C,PHTF2" MicroRNA hsa-miR-502-3p:mirSVR_highEffct hsa-miR-502-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-32 7.47E-29 4.07E-32 3.75E-31 87 521 "ACTN1,NDRG2,KIAA1324,ARHGAP20,OGT,APAF1,USP37,BCL7A,DST,JAZF1,PTBP2,SLC25A14,ZMYM4,CNN3,RCHY1,HAPLN1,RNF14,DCAF8,ZNF337,DAPK1,RHOBTB1,NR1D2,CPEB2,DNAJB6,KCTD3,FCGR1A,UBE2E3,AGAP3,ATP13A4,JKAMP,NBEA,ATP6V1H,STAU2,GABRB3,DISC1,MSTN,GLI2,TDRKH,MCHR1,GRIA2,CIT,BVES,RBPJ,KCNN2,CYP27C1,MBD1,TM6SF1,AFDN,MYCN,NEFM,NF1,CLDN11,PCDH9,PCSK5,PMP22,CCDC144B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,MAPK9,BDNF-AS,ACSM5,SH3TC2,ZFHX4,RPL15,ATP8B4,SATB1,SEPHS1,EPC1,RCOR3,TRERF1,HECW1,KDM4C,PEG10,ZBTB43,SEPT8,PRRC2C,ITGB3BP,HEY1,UBE2H,KCNT2,EML6,ZNF189,AMN1,GAN,LAS1L" MicroRNA hsa-miR-197:mirSVR_highEffct hsa-miR-197:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.41E-32 7.90E-29 4.30E-32 3.96E-31 98 654 "CC2D2A,TAOK1,PKP4,PHYHD1,SPTBN4,PLA2G4C,SLC4A4,BACH1,ZNF599,CAST,CBLN1,CBR1,ARHGAP33,L3MBTL4,RAB28,ARMC8,SLC4A8,TRIM69,SNCAIP,VAC14-AS1,PDE4DIP,FAM169A,PITPNM3,HDAC9,TCAF1,GIT2,GSDME,DLX1,GRIN3A,DNM1,DPH1,EBF1,EDNRA,EDNRB,MRNIP,EPB41,CEP85L,EYA1,TAOK3,FCGR1A,CEP78,SLC37A3,WDFY3-AS2,TDRKH,CCDC184,GRIA2,PLCD4,CLASRP,SMAP1,ZNF181,ZIC5,JAK2,KCND2,KCNN2,STXBP5,PPM1L,NF1,OXTR,GPR85,OLA1,PLCL1,ING3,SEPT4,PPM1B,CCDC144B,EPDR1,GRAMD1C,TMEM145,SUSD4,RDX,C12orf49,ELP2,CCDC102B,FBXW7,SCN7A,SCN8A,SUPT20H,SH3GL3,NLGN1,SLC2A5,CCDC88A,UHRF1BP1L,KDM4C,ZNF302,SST,SS18,DIP2A,TAL1,SATB2,ITGB3BP,MTMR14,PRRT1,UBE3A,RICTOR,MDH1B,PDSS2,FZD3,SNX14" MicroRNA hsa-miR-22:mirSVR_highEffct hsa-miR-22:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-32 8.35E-29 4.55E-32 4.19E-31 97 642 "FMNL2,RNF157,PLEKHH1,DPY19L2P4,OSBPL6,FAM135A,AMPH,ARRB1,RGS20,CDK13,TTLL9,BACH1,SGCE,WASF1,VXN,CERS5,ZMYM4,SLIT2,IGLON5,CSF1R,VCAN,PLCXD3,ARMCX4,MYEF2,C2CD2L,SNAP91,PDCD6IP,EDNRA,PHF20L1,VPS13B,EPB41L2,EPHB1,ERCC2,MRPL10,ETV1,DNAJC27,RPS6KC1,SEC23B,UFM1,FAM49B,ZNF605,IP6K3,SYT17,GATM,SESN1,ZNF638,PCLO,GUCY1B1,ARHGAP36,AGBL5,HNF4G,SMAP1,MSL1,INPP5B,MAT2A,MEIS2,PPM1L,POC1B,NEFM,NELL2,NF1,NOVA1,DUSP26,GPSM2,PLCL1,MAPKAP1,WDR25,TMEM255A,ERI2,RIC8B,ELP2,NEK11,FBXW7,SPIN3,CHD9,ANKRD6,SEPHS1,KDM3A,ZC3H13,NXT2,ADHFE1,PRRC2C,NUDT10,SATB2,SYNE1,SIRT1,ITGB3BP,MTMR14,KAT6B,PDSS1,ZKSCAN5,CLDND1,ZBTB38,MAP3K12,KCNAB1,NLRP3,LAS1L" MicroRNA hsa-miR-6778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-32 1.00E-28 5.44E-32 5.01E-31 100 681 "AS3MT,XKR4,RNF157,ESYT2,MTA3,AK2,ZNF578,TAOK1,CDC14B,SLC4A4,ATP1B3,ALDH7A1,LDHD,GYG2,CACNA1A,ZBED1,PLAA,STOML1,IGLON5,RTTN,ENTPD4,HINFP,CSNK1E,SOCS5,KIAA0408,RIPOR2,TMEM170A,KRBA2,CNNM1,IRAK4,RGS17,TUBD1,MTSS1L,SLC43A2,MRPL37,TLR7,FDFT1,FGFR1,PCYOX1,APOPT1,PDLIM5,CELF1,MSANTD4,KIAA1841,SRCAP,RAB40B,RNF165,HAS2,DDX19B,EID2B,SHISAL1,NKD1,KCNK3,LIMS1,NCOA7,GPR155,MBD1,P2RX7,PIK3C2A,ZNF655,FAM216A,ZNF426,STRN3,FITM2,GDPD1,PIGG,ZSCAN2,ZNF844,NWD1,GTDC1,DCUN1D2,C12orf49,PGBD4,PTGR2,SCN2B,GALNT10,HSPA4L,ZFP30,PEX26,FAIM2,FAM126B,SP2,SSTR2,DIP2A,STAC2,ZC3H4,AGTPBP1,KIAA0930,GPRIN3,PCDHA6,ZMAT3,ARL10,CBX5,ERCC6L2,PARD3,CFAP298,AGMO,ZNF70,ZNF225,MPPE1" MicroRNA hsa-miR-889:PITA hsa-miR-889:PITA_TOP PITA 1.84E-32 1.03E-28 5.59E-32 5.15E-31 64 280 "ACTN1,PCDH19,CEP126,OGT,UPRT,PPP4R4,NUMB,CACNB4,SOCS6,AKAP5,C2CD2,OSBPL3,DCAF8,ZFYVE16,WDR20,DNAJB6,EDIL3,GPHN,ETV1,FGF12,DENND2A,GLUL,MIER3,NEGR1,DHX35,INSM1,MAN2A2,MBNL1,MITF,MYCN,NRCAM,PCSK1,ZNF655,MAPKAP1,MINDY2,MTMR10,PTPRB,PTPRD,KHDRBS2,UBR7,PCMTD2,MCMBP,SEMA6D,CCDC88A,SLC12A2,FAM219A,PDZD2,VPS13A,FBXW11,TCEA1,TCF4,SATB2,CUX2,TRIM2,SYNE1,C18orf54,TRPS1,USP1,VSNL1,ZIC1,ZBTB38,PHTF2,NETO2,RNF146" MicroRNA hsa-miR-892a:PITA hsa-miR-892a:PITA_TOP PITA 2.07E-32 1.16E-28 6.28E-32 5.78E-31 62 262 "HECW2,AMPH,CAST,SEPT7,EVI5L,CLGN,FOXN3,QKI,MAP4K4,AKAP6,RBM39,SLITRK5,LONRF1,DYNC1I1,CPEB2,KMT5B,NRN1,MEX3B,EVL,AHDC1,GPT2,MAP4K5,MIER3,KCND2,MBNL1,NF1,NPTX1,OLA1,NLGN3,ANKRD16,LRRN3,PTPRG,TMEM255A,RDX,GTDC1,NCBP3,SATB1,CSRNP3,CHD9,R3HDM2,SLC8A1,TET1,CPEB4,RCOR3,FNBP1,PEG10,DDN,KANK1,ANKRD12,MTCL1,CAMTA1,ZEB1,FLRT2,XPO1,XRCC4,ZNF711,KCNT2,EMSY,NAV3,WNK3,FAM13C,KAT6A" MicroRNA hsa-miR-193a-5p:mirSVR_highEffct hsa-miR-193a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.07E-32 1.16E-28 6.29E-32 5.79E-31 87 524 "KCNH8,PCDH10,ZNF687,RGS20,NUMB,SEC11C,RGS11,BMPR1B,CASTOR3,JAZF1,CACNA1G,KALRN,RUNX1T1,NFS1,DCLK1,ZMYM4,EPS15L1,SLC4A8,CLIP3,CSF1,CSNK1G3,PHACTR3,GREB1,HDAC9,RHOBTB1,NR1D2,CPEB2,ABCC5,PHF20L1,CALCRL,ERBB2,FGF11,NOP56,DISC1,ZNF638,CBX1,ZNF496,RNFT2,MSL1,KCNN2,ADAM22,NOVA1,NUCB2,ZNF827,PDE1C,OLA1,FAM218A,C19orf57,MASP1,RELN,ZSCAN32,PTPRN2,ZSCAN2,ZNF844,RBBP6,HKR1,CARF,RORB,RPE,ABCA11P,SLC22A4,COA1,TTC17,SSPO,SULF2,PLCB1,ZFP90,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,TMPO,ELP5,TTC3,RPL7L1,GORASP1,UGT8,LMF1,MKRN3,FAM13C,TRAM2-AS1,NETO2" MicroRNA hsa-miR-4264:mirSVR_highEffct hsa-miR-4264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.23E-32 1.25E-28 6.77E-32 6.23E-31 89 548 "KCNH8,ACADM,AXIN2,PWWP2A,ABCD2,DDO,SEMA4G,SPTBN4,ARRB1,ADAM23,KALRN,ZMYM4,LHX2,CNTN1,IQCK,AKAP6,FAM171B,GDA,SEC24C,ERC2,HDAC9,KATNAL2,TCAF1,ARHGAP24,ZFYVE16,IST1,AIF1L,RUSC2,ZC3H11A,EEF1D,ENPP6,SIRPB1,ABCA8,KAT8,SMC2,FAM49B,GALNT15,DISC1,GFER,ZNF276,FAM19A2,ATXN2L,GABARAPL2,MSL1,FAM95B1,KIF2A,PAXBP1,MBNL1,LRP1B,MEIS2,MSR1,SFR1,IGSF11,OCRL,ZNF713,P2RY1,RETREG1,PCDH18,RETREG2,HYDIN,PTPRG,TMLHE,ROBO2,YY1AP1,FBXW7,ATP8B4,FAM192A,ATXN7,TRA2B,FHOD3,SNRPN,ZSCAN29,ELOVL4,TMEM150C,SYT1,PCDHB3,PUM2,C9orf85,AMACR,TRO,DCBLD1,FAM155A,VLDLR,XRCC4,ZSCAN26,SMARCAD1,EMSY,FZD3,NETO1" MicroRNA hsa-miR-939:mirSVR_highEffct hsa-miR-939:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-32 1.38E-28 7.47E-32 6.87E-31 85 502 "ABCF1,NDRG3,ADCY6,CCDC85A,PTCHD1,ZFAT,PHF12,PKP4,PPFIA3,SEMA4G,TTLL9,ADGRB1,RGS11,CA4,LURAP1,USP2,PLEKHB1,NDST3,PPT2,MAP4K4,ARMC8,SLC35F1,CSF1,SEC24C,KATNAL2,DCAF8,CHRDL1,FIS1,EDN1,C3orf18,MFSD10,MRVI1,UBE2E3,IP6K2,AGAP3,DCTN2,HVCN1,AK8,USP21,CELF1,FYN,STARD3,LOXL3,GPD2,FUT10,PLCD4,GRIK5,SERP2,KAT7,PADI2,ATXN2L,ARHGAP36,LRRC25,KIF5A,NCOA7,MAN2A2,DBNL,NBL1,NTRK3,ZNF655,PPP2R2B,MAPK4,RASGRF2,ZDHHC4,SETD5,CLIP1,PRCD,PEAR1,FBXO11,R3HDM2,ST6GAL1,PEX26,BTBD7,SMARCD3,UHRF1BP1L,PBLD,NAT16,CYB561A3,THRA,SLC35A4,ZNF70,TMEM198,DNALI1,WNK3,DOCK8" MicroRNA hsa-miR-760:TargetScan hsa-miR-760 TargetScan 2.62E-32 1.47E-28 7.95E-32 7.32E-31 78 424 "EMILIN3,ADD2,MTUS1,KIAA1324,C6orf89,FAM131A,ARNTL,ATP2B2,MTMR2,CACNA1I,CAMK2G,DGKI,CDR1,MAGED1,NRG2,IGDCC3,NCOR1,SEC24C,CNTNAP2,PUM1,DGKG,ELMSAN1,FAM107B,DRP2,PHC2,HEYL,GOLGA7,EIF5,EIF1,EPB41,MRVI1,FGF1,ANKFY1,DCTN2,AKAP3,GALC,GFER,RNPS1,GSTM5,KAT7,ATOH8,NXPH3,HMGCR,LIFR,LSAMP,MATN2,MBNL1,MMP16,MOV10,GIT1,MYO5A,OPRL1,PDPK1,PFKFB3,SDK2,PPP2R5E,PRKAB2,RAD51D,DPF2,GTDC1,NUDT11,ATXN7,SCN2B,SCN8A,PEAR1,GALNT10,AMBRA1,FAM126B,HECW1,ARHGAP26,DBNDD2,PHLDB1,CLASP1,AP4E1,CBX5,PIK3R5,CLIP2,EVI5" MicroRNA hsa-miR-665:mirSVR_highEffct hsa-miR-665:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-32 1.47E-28 7.96E-32 7.33E-31 96 634 "KCNH8,SYS1,KDM5D,NDRG2,AP2A2,ADGRF5,AMPH,OGT,FGD2,UPRT,PPFIA3,CCAR2,CHID1,TTLL9,NRP2,CFLAR,RAB29,CAST,CCK,MAGI1,RCBTB2,NDST3,ABCG2,FAM149A,SLC4A8,TOGARAM2,MYRIP,OSBPL3,PDE4DIP,TM9SF4,DDX46,SGSM2,EXOG,DYNC1I1,DPH1,DPP6,PDCD6IP,ELN,EXTL2,FCGRT,GORAB,OLFM1,EVL,SEMA4D,SLC37A3,NOP56,WDR83,GFRA2,GNAO1,PLCD4,SERP2,GRM8,VSIG4,KCNN2,KCNN3,MEIS1,SAMD5,NNAT,CNOT4,DNHD1,NUCB2,OXTR,TREM2,PFKFB2,PLCB2,ING3,RASGEF1B,MAPK9,GDPD2,SPDL1,USP47,RASGRF2,RFX2,EXD2,MEG3,ZNF331,CASC3,KANSL3,PKNOX2,IFT122,ERC1,CEP68,SULF2,ASTN2,PJA1,SYNE1,RNF216P1,VWCE,ERCC6L2,SMUG1,DCBLD1,TSC1,DNALI1,TRIM16L,PDSS2,TRAM2-AS1" MicroRNA hsa-miR-597:mirSVR_highEffct hsa-miR-597:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-32 1.57E-28 8.49E-32 7.81E-31 83 480 "PWWP2A,SLC24A4,C1QTNF3,SRPX,ANK2,DNAH17,ATP6V1G2,PTBP2,VXN,CAST,METTL6,CFL2,CHGB,CHN2,NRXN3,RCHY1,MYRIP,SLC35F1,GDA,ARHGEF4,RUBCN,ARMCX4,DMTF1,DNAJB6,E2F6,FSD1L,YAF2,NCALD,FGF14,AGAP3,PSD2,PDLIM5,MSANTD4,IP6K3,GLYR1,GPD2,RNF165,USP51,NEGR1,HSF2,IL6ST,ZNF678,KCND2,HECTD2,MBD1,KITLG,MXI1,CNOT4,PDE1C,SEPT4,EPDR1,MAPK9,GRAMD1C,MASP1,RELN,WBP1L,NUDT11,RNASEL,EXD2,NEK11,NCBP3,SEMA6D,ATXN7,STUM,SGK1,CPEB3,FHOD3,BTBD3,RCOR3,PDZD2,SP4,RGL1,SZT2,OBSL1,THRA,KAT6B,RPRM,ZNF19,SH3GLB2,TMEM178A,CIAPIN1,FIP1L1,SMIM8" MicroRNA hsa-miR-122*:mirSVR_lowEffct hsa-miR-122*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.02E-32 1.69E-28 9.15E-32 8.43E-31 77 414 "XKR4,UNC5A,ZNF687,MYH7B,BCAS1,ARNTL,ADAM23,ADGRB3,SYNJ2,PTBP2,DCLK1,QKI,COX4I1,AHCTF1,FAM131B,YTHDC1,ZNF804A,KIAA0319,DDX46,DTNA,KLHL5,ETV1,ZNF461,GTF2IRD2,WDR83,JKAMP,SMC2,APOPT1,CELF1,GABRG1,TNRC6A,SERP2,HMGCL,HSF2,IFI16,ITGAM,SYTL4,MEF2C,MYO9A,DNHD1,OXTR,FXYD1,PDZRN4,STRN3,SLC25A36,PBRM1,EPHA10,ARMH4,NCBP3,FOXRED1,FHOD3,FAM81A,PKNOX2,SLC6A8,SLC14A1,ATF7IP,SMARCA4,MAST1,MBD5,KDM4C,CDK19,ZNF106,TIAM1,ERCC6L2,CSMD1,RUNDC3B,OSBP2,ZNF709,CFAP298,CADM2,PRTFDC1,DNALI1,PDSS2,FBXO36,ACTR3B,RNF170,LAS1L" MicroRNA hsa-miR-3131:mirSVR_lowEffct hsa-miR-3131:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-32 1.72E-28 9.30E-32 8.56E-31 84 492 "RALGAPA1,DGCR6,XKR4,AP2A2,TBC1D14,ZNF687,MAP4K3,TNRC6C,MADD,SLC4A4,CARMIL3,ADAM15,LINC00847,CACNA1B,CACNA2D1,THSD7A,KALRN,TIGD7,CHN2,CLCN3,PICK1,FAM149A,AKAP6,CNTNAP2,PNPLA8,DCAF4,ZNF337,TMCC2,EDN1,EDNRA,TUBB3,NOP56,TMEM175,MEGF10,SULT1C4,CRCP,HTATSF1,LILRA2,GRIA2,FRMD3,ATXN2L,ACOT7,CPT1C,MYLK2,SOWAHA,SLC35G1,TTYH2,AQP11,TM6SF1,PTOV1,TAGLN3,NFIX,NTRK3,NLE1,MAPKAP1,PIGG,PTPRB,PTPRG,SLC25A36,ZNF532,CARF,SATB1,CSRNP3,SH3GL3,SEC31A,ZNF430,SLC12A4,CPEB4,POGZ,STAC2,KANK1,SYN1,PDLIM2,SIN3B,ERCC6L2,RUSC1,TTTY15,UCHL1,PLPPR2,ANKS1B,CIAPIN1,SEMA3B,UBE3B,DPF3" MicroRNA hsa-miR-140-5p:PITA hsa-miR-140-5p:PITA_TOP PITA 3.58E-32 2.00E-28 1.08E-31 9.95E-31 64 283 "SYS1,GALNT16,ADCY6,ZNF608,OSBPL6,OGT,DPP10,ZBTB10,NCOA1,WASF1,FOXN3,CNOT8,CNR1,CNTN1,RBM39,CSNK1G3,ERC2,HDAC4,SCRN1,DMTF1,DPYSL2,EIF4G2,EPB41L2,ERBB4,ANKFY1,CELF1,SRCAP,PPARGC1A,TCERG1,ADAMTS6,CYP27C1,TTYH2,MARK1,MPP2,NFE2L2,NFYA,ZNF827,GPR85,STRN3,DRAM2,WBP1L,TMEM260,RIC8B,NUDT11,PBRM1,RTN1,SEMA6D,SUPT20H,HSPA4L,FAM102A,SOX11,MYCBP2,ERBIN,ST5,SATB2,DICER1,HEY1,RIMBP2,R3HDM1,FLRT2,POLR3H,NAV3,WNK2,FXR1" MicroRNA hsa-miR-21-5p:TargetScan hsa-miR-21-5p TargetScan 3.58E-32 2.00E-28 1.08E-31 9.95E-31 64 283 "CASKIN1,ABCD2,BCL7A,DST,KRIT1,CNOT8,HECTD1,CNTFR,PHF14,PYGO1,HDAC9,ARHGAP24,SCRN1,AIF1L,FAM107B,EDNRB,ANKRD46,HIPK3,RASGRP1,FAM13A,EGR3,PLEKHA1,PAN3,ARMCX1,SCML2,NBEA,GLYR1,NEGR1,MSL1,RBPJ,IL6R,IL6ST,IL12A,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,POC1B,NELL2,PDE3A,PIK3R1,PURG,PPP3CA,MAPK10,BCAS3,RDX,PBRM1,ROBO2,MCMBP,AP1AR,SATB1,CSRNP3,CPEB3,FBXO11,FAM126B,PDZD2,MPRIP,CADM2,RGS7BP,RTN4,KAT6A,NETO2" MicroRNA hsa-miR-574-5p:Functional MTI Functional MTI miRTarbase 3.58E-32 2.00E-28 1.08E-31 9.96E-31 77 415 "PTCHD1,CARNS1,MARCH4,PCDH10,BCAS1,ARRB1,MARCH3,THSD7A,RUNX1T1,FOXN3,TMEM184B,IGLON5,PPP1R16B,PYGO1,LONRF1,DBT,JAKMIP2,TMEM130,SV2B,CHRDL1,DMD,CDON,KATNAL1,TBC1D16,FGF14,UBE2E3,EFCAB2,C15orf41,MMADHC,GLI2,GLYR1,BVES,SYNPO,ZDHHC15,IGF1,NKD1,KCNB1,KLHL23,KCNQ3,SMAD9,MAP2,MITF,HS6ST3,MYO5A,NEXMIF,OXTR,GPR173,NLGN3,ZNF655,PLEC,SDK2,PRKCB,MAPK10,SH3TC2,RGS4,PGBD4,KIAA0895L,KCNIP3,SATB1,CSRNP3,ZHX3,NMNAT2,ARHGEF9,MGRN1,ATMIN,ZEB1,TRIM2,THRA,NR2E1,DOK6,VSNL1,KCNK12,ELFN1,DPYSL5,STOX2,KAT6A,ZDHHC20" MicroRNA hsa-miR-31:PITA hsa-miR-31:PITA_TOP PITA 4.00E-32 2.24E-28 1.21E-31 1.11E-30 58 229 "ABR,CLK4,NDRG3,ADCY6,RTL9,APBB2,NUMB,CCAR2,JAZF1,CALM1,CAMK2G,ARHGEF2,CLCN3,QKI,PREPL,DCAF8,RHOBTB1,EIF5,SLC43A2,FOXO3,ANKFY1,AFF2,KHDRBS3,STAU2,GRB10,MAP4K5,ATXN2L,BACH2,CAMK2N2,CHIC1,AFF1,IGSF11,PIK3C2A,RETREG1,PPP3CA,TMEM260,TMEM145,PRRT2,SNX22,SEMA6D,WDR37,SEPHS1,SOX11,CLASP2,KANK1,PLCB1,TACC1,SATB2,TCF12,TEK,DICER1,CSMD1,TNS1,NR2C2,KCNE5,OSBP2,FZD3,RTN4" MicroRNA hsa-miR-455-3p:PITA hsa-miR-455-3p:PITA_TOP PITA 4.30E-32 2.41E-28 1.30E-31 1.19E-30 61 256 "KCNH8,FMNL2,AP2A1,OSBPL8,SEMA6A,PPFIA3,TMEFF1,ATP1B3,MAGI1,CACNA2D2,SOCS6,LHX2,CLTC,SLC35F1,SLITRK5,CHRDL1,CDON,DRP2,FRY,TMEM35A,ETV1,FGFR3,BAIAP2,MEX3B,GABRG2,FERMT2,GPD2,HAS2,GABARAPL2,KCND1,PACRG,MYO6,NFIX,NOVA1,PCDH9,PIK3R1,RETREG1,PPP2R5E,PRKAB2,RELN,USP47,PBRM1,SALL1,SLC8A1,SLC12A2,CDK19,RBM26,SS18,SYN2,TCF4,DMXL2,PUM2,FRYL,SIRT1,SLC44A1,HEY1,VSNL1,XPO1,MICU3,EMSY,CPNE4" MicroRNA hsa-miR-590-5p:TargetScan hsa-miR-590-5p TargetScan 4.46E-32 2.49E-28 1.34E-31 1.24E-30 64 284 "CASKIN1,ABCD2,BCL7A,DST,KRIT1,CNOT8,HECTD1,CNTFR,PHF14,PYGO1,HDAC9,ARHGAP24,SCRN1,AIF1L,FAM107B,EDNRB,ANKRD46,HIPK3,RASGRP1,FAM13A,EGR3,PLEKHA1,PAN3,ARMCX1,SCML2,NBEA,GLYR1,NEGR1,MSL1,RBPJ,IL6R,IL6ST,IL12A,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,POC1B,NELL2,PDE3A,PIK3R1,PURG,PPP3CA,MAPK10,BCAS3,RDX,PBRM1,ROBO2,MCMBP,AP1AR,SATB1,CSRNP3,CPEB3,FBXO11,FAM126B,PDZD2,MPRIP,CADM2,RGS7BP,RTN4,KAT6A,NETO2" MicroRNA hsa-miR-650:PITA hsa-miR-650:PITA_TOP PITA 4.97E-32 2.78E-28 1.50E-31 1.38E-30 54 196 "ASIC1,NCOA1,KIF1A,SYNJ1,CAMK2G,DLGAP2,CHN2,CPNE6,QKI,PICK1,LETMD1,MYRIP,FAM171B,NCOR2,CSNK1G3,RIMS4,SNPH,KLHL3,CELSR3,EGR3,CORO2B,PSD2,OGA,GPR162,PCLO,GRIN2D,RNF165,ZIC5,IBA57,MITF,ZNF827,PRTG,PDE1B,PIK3R1,CCSER2,PMP22,RETREG2,RIPOR1,CYB561D1,ROBO1,SCP2,FAM102A,FAM214B,SOX11,FBXW11,TCF4,SLC44A1,HEY1,CBX5,R3HDM1,DOK6,NR2C2,KCNE5,UBE3A" MicroRNA hsa-miR-580:PITA hsa-miR-580:PITA_TOP PITA 5.70E-32 3.19E-28 1.72E-31 1.58E-30 68 324 "KCNH8,OSBPL1A,DPP10,CAMK2A,SEPT7,MAGI1,DLGAP2,FOXN3,CLTB,TBPL1,CLOCK,CSNK1G3,PUM1,MAML1,IST1,GUCD1,ALKBH8,RAB39B,PDCD6IP,FRY,KCTD3,TMEM35A,ACSL4,SEMA4D,AFF2,NBEA,ATP6V1H,MAP4K5,BACH2,MIER3,AGFG1,KIF5A,MBNL1,MIA2,XRRA1,PCSK1,RETREG2,DRAM2,PPP3CA,CEP41,PTK2,PBRM1,ZFHX4,ROBO2,ZC3H14,AP1AR,SATB1,SCN8A,CPEB3,ATF7IP,TMCC1,PEG10,STAU1,RGL1,STAC2,SYPL1,CAMTA1,TCF4,FRYL,DICER1,TIAM1,NR2E1,NR2C2,TOM1L2,REEP1,SLC17A7,PCBP4,RGS7BP" MicroRNA hsa-miR-15a-5p:Functional MTI Functional MTI miRTarbase 6.31E-32 3.53E-28 1.90E-31 1.75E-30 102 717 "AXIN2,FZD9,USP31,PWWP2A,CASKIN1,HACE1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,CDC14B,CASK,ARHGDIA,ZBTB10,KIF1A,DOCK11,BCL7A,MTMR3,CA8,RUNX1T1,CCNT1,ENTPD6,CLCN3,TMEM184B,CNN3,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,DMPK,USP3,CPEB2,DMTF1,PDCD6IP,FCF1,HEYL,PLEKHA1,RAB9B,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,RGPD5,MSANTD4,ZNF559,RNPS1,RAB40B,GNAL,NEGR1,MSL1,RBPJ,FAM69A,LAMP2,CHIC1,SCAMP5,MN1,MYO5A,OCRL,ETFRF1,PDE4D,PIK3R1,PRIMPOL,PSAT1,PTPRD,RBBP6,RET,RNASEL,ZFHX4,RNH1,SALL1,HSPA4L,CPEB3,ANKRD36,TSPYL2,KANK1,PRRC2C,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,CABIN1,TPM2,NR2C2,TUBB2A,UBE2H,WIPF1,KLC2,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-1826:PITA hsa-miR-1826:PITA_TOP PITA 6.61E-32 3.70E-28 1.99E-31 1.83E-30 54 197 "GALNT13,MTUS1,SEMA6A,CDC14B,ZBTB10,DCLK1,SLC35F1,USP6NL,RASSF2,KCTD8,MTX3,WDR20,DLX1,EPB41L2,TAOK3,FGF13,NBEA,BRSK1,MTHFD2,PTPRT,BVES,NCKAP1L,NEGR1,SMAP1,LRRCC1,MARK1,MXI1,MYO6,ZC3H12B,NF1,NFYA,CNOT4,NOVA1,OPA1,GPSM2,MAPKAP1,GDPD1,TMEM260,REV3L,SLC25A36,ZFHX4,SALL1,CPEB3,SOX11,STAU1,TTBK2,NSFL1C,AGTPBP1,TCF4,TRIM2,NACC2,TRIM9,JMJD1C,SOCS4" MicroRNA hsa-miR-1306:mirSVR_lowEffct hsa-miR-1306:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.69E-32 3.74E-28 2.01E-31 1.85E-30 81 463 "ACADM,PLEKHH1,OSBPL6,WDR35,TXNDC16,ALK,FAM131A,PPFIA3,SEMA4G,MADD,CASK,ARNTL,RGS20,JAZF1,AP1M1,CAST,LDB2,CHRNA4,EPS15L1,CNN3,AKAP7,COL11A2,NCOR2,CSNK1G3,SGSM2,TMCC2,DLX1,CPEB2,SLC12A6,E2F5,AASDH,EDN1,SUGP2,TENM1,EPB41L2,NRN1,GORAB,BAIAP2,TMEM164,AMOTL2,NOP56,KHDRBS3,FYN,TNRC6A,ZNF782,GPR37,ADAMTS13,ZBTB49,VSIG4,KCNN1,STXBP5,KTN1,STMN1,LRP1B,NFIX,NOVA1,NRCAM,NTRK2,IGSF11,LRP12,GTDC1,FBXW7,ABCA11P,SATB1,SEC14L1,SUPT20H,LIMCH1,ERC1,PCDHB3,ARHGAP9,CYB561A3,TRIO,AMACR,KCNE5,TTC3,LINC00689,ZBTB14,SLC38A1,SEMA3B,PPP1R3F,JPH3" MicroRNA "AAGCCAT,MIR-135A:MSigDB" "AAGCCAT,MIR-135A:MSigDB" MSigDB 6.83E-32 3.82E-28 2.05E-31 1.89E-30 67 315 "MTUS1,GAS7,PDE8B,NCOA1,ATP2B2,BACH1,ARHGEF7,KALRN,ARHGEF2,KCNAB3,DLGAP2,FOXN3,QKI,ARHGEF6,PCYT1B,ZNF385A,SLC35F1,ENTPD4,ARHGEF4,RIMS2,LONRF1,PITPNC1,MYEF2,GOLGA7,EXTL2,RGPD5,SYT3,NBEA,STAMBP,ZNF44,GABRG1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,PSIP1,NEGR1,SHISA6,IL6ST,JAK2,KCND1,MAT2A,MEF2C,PDE4A,GPR85,DRAM2,DIRAS2,SNRK,ELOVL2,PTK2,SEMA6D,SCN2B,MRAS,MAPKBP1,FAM219A,RGL1,PLCB1,CUX2,SIRT1,SLC44A1,TMEM9,VLDLR,NDRG4,EVI5,ADAMTS9,PHTF2,SOCS4" MicroRNA "AAGCCAT,MIR-135B:MSigDB" "AAGCCAT,MIR-135B:MSigDB" MSigDB 6.83E-32 3.82E-28 2.05E-31 1.89E-30 67 315 "MTUS1,GAS7,PDE8B,NCOA1,ATP2B2,BACH1,ARHGEF7,KALRN,ARHGEF2,KCNAB3,DLGAP2,FOXN3,QKI,ARHGEF6,PCYT1B,ZNF385A,SLC35F1,ENTPD4,ARHGEF4,RIMS2,LONRF1,PITPNC1,MYEF2,GOLGA7,EXTL2,RGPD5,SYT3,NBEA,STAMBP,ZNF44,GABRG1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,PSIP1,NEGR1,SHISA6,IL6ST,JAK2,KCND1,MAT2A,MEF2C,PDE4A,GPR85,DRAM2,DIRAS2,SNRK,ELOVL2,PTK2,SEMA6D,SCN2B,MRAS,MAPKBP1,FAM219A,RGL1,PLCB1,CUX2,SIRT1,SLC44A1,TMEM9,VLDLR,NDRG4,EVI5,ADAMTS9,PHTF2,SOCS4" MicroRNA hsa-miR-1827:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.21E-32 4.03E-28 2.17E-31 1.99E-30 111 837 "ABCF1,AS3MT,XKR4,NDRG3,KLHL32,ELFN2,ADD2,SLC24A4,TXNDC16,LTBP4,TRMT9B,APAF1,CPNE5,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,DDR1,ZNF555,PTBP2,ISPD,SLC16A4,C1orf52,CFL2,NRXN3,LETMD1,AKAP5,SLC35F1,IPCEF1,USP6NL,SEC14L5,TMEM170A,DNAL1,ELMSAN1,SGSM2,DNAH9,SLC29A4,E2F6,HEYL,RASA4,IRAK4,MRNIP,MTSS1L,VPS26C,ANKMY1,ZNF585B,ZNF589,PCYOX1,ATP13A4,TRMO,MSANTD4,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,ZNF638,GNG4,BVES,DDX19B,AGBL5,ZNF546,IBA57,KLHL23,SMAD9,MAP4,MATN3,PPM1L,MXI1,NBL1,SLC11A2,CCSER2,PLEC,PLXNB1,RETREG2,MTMR10,PTPRE,TMEM145,ZNF844,QDPR,ZNF793,MSANTD2,SETD5,GSTCD,SNX22,PTGR2,SALL1,SH3BP2,MYO18A,SLC2A5,LIMS2,ATF7IP,IQSEC2,CDK19,LHPP,ZSCAN29,ZC3H4,FAM208A,USP22,NACC2,PPIL6,SSBP2,TUBB2A,ZNF70,MPPE1,PARP11" MicroRNA hsa-miR-891b:PITA hsa-miR-891b:PITA_TOP PITA 8.23E-32 4.61E-28 2.47E-31 2.28E-30 62 268 "PCDH19,OSBPL1A,SYNJ1,LDLRAD4,LDB2,NRXN3,FAM171B,OSBPL3,RIMS2,LONRF1,KLHL3,DYNC1I1,EGR3,ETV1,SUCO,FOXO3,PDLIM5,TNRC6A,TMEM121B,FAM19A2,MIER3,MAP2,NEXMIF,NEK1,NFYA,NTRK2,ENPP2,GPR85,PIK3R1,GRAMD1C,PRPSAP2,SNRK,PTPRD,GTDC1,FBXW7,SALL1,SCP2,CHD9,NLGN1,ABLIM3,CCDC88A,SLC12A2,SOX11,NMNAT2,SS18,ELOVL4,SYN2,SYPL1,COBL,TCF4,SATB2,TCF12,AKTIP,RIMBP2,KAT6B,SSBP2,TUBB1,FLRT2,ZFAND5,WNK3,FXR1,FRMD6" MicroRNA hsa-miR-488:PITA hsa-miR-488:PITA_TOP PITA 8.48E-32 4.75E-28 2.55E-31 2.34E-30 68 326 "FMNL2,ADRB2,KLHL13,PCDH19,ZNF687,SYNJ1,CALM1,PTBP2,FOXN3,CHN2,NRXN3,KLHL3,SLC12A6,PHC2,TENM1,RAB9B,FGFR3,FAM49B,KHDRBS3,GABRB3,CPLX2,PRRC2B,GRIN2D,PTPRT,IGF1,ZIC5,MAP2,MAT2A,MBNL1,NEXMIF,OCRL,PDE4B,PFKFB3,PIK3R1,XRN1,PCDH18,LRP12,PKIA,GRAMD1C,QRICH1,TMEM260,SH3TC2,KHDRBS2,FIGN,AP1AR,SHC4,CCDC88A,SNCA,FAM126B,TEX2,NKAIN2,ERBIN,SYT1,CAMTA1,DICER1,SLC44A1,CSMD1,AMACR,UBC,PLEKHH2,GDPD5,PRDM10,SLC17A7,KCNAB1,WNK3,KAT6A,NETO2,ST8SIA2" MicroRNA hsa-miR-940:PITA hsa-miR-940:PITA_TOP PITA 9.51E-32 5.32E-28 2.85E-31 2.63E-30 63 278 "XKR4,UNC5A,ZNF608,PCDH19,DOC2A,PITPNM2,MARK4,EIF4G3,N4BP2L1,CAMK2B,EVI5L,CFL2,PICK1,ZNF385A,HAPLN1,CS,SIPA1L1,DCAF8,SGSM2,DNM1,ABCC5,EDIL3,APH1A,EGR3,RASGRP2,PRMT5,HPCAL4,BRSK1,CPLX2,STMN2,LINGO1,BACH2,IGF1,IBA57,KCND2,NCOA7,CHIC1,MEF2C,TRHDE,SCHIP1,RETREG2,EPB41L4B,MAPK10,PTK2,TMEM145,MORC4,SETD5,CYB561D1,SCN2B,PPP4R3A,RCOR3,TMCC1,NMNAT2,PEG10,ZC3H4,ASTN2,SIRT1,ZMAT3,HEY1,CBX5,TRPS1,CADM2,GAL3ST3" MicroRNA hsa-miR-193b:mirSVR_highEffct hsa-miR-193b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.81E-32 5.49E-28 2.94E-31 2.71E-30 77 421 "KCTD16,RTL9,HACE1,ALCAM,UPRT,STX16,CALB1,THSD7A,CALM1,SPAG9,RUNX1T1,USP6,PLAA,TPP1,COL4A5,EARS2,ZC3H11A,WDR20,E2F6,RABEPK,HVCN1,ST6GALNAC3,RAPGEF6,DISC1,ARFIP1,PPARGC1A,RAB30,GNAO1,ADAMTS13,AGBL5,ZNF181,LAMP2,STMN1,LIMS1,MBD1,MYCN,NF1,NOVA1,GPR137C,PDCD2,CEP41,MAPK10,DEF8,CNTLN,FAT4,MSANTD2,MORC4,CARF,GLDN,LRRK2,SCP2,ELMO2,SNRPN,SPATA7,BDP1,SP4,ERBIN,ST5,SULF2,SEPT3,SLC37A2,C12orf76,CAMTA1,AGTPBP1,DMXL2,RPGRIP1L,USP32P1,R3HDM1,SMUG1,RUSC1,PLEKHH2,CCDC14,LINC02210,NELFE,ADAMTSL3,IFT88,RNF146" MicroRNA hsa-miR-3142:mirSVR_highEffct hsa-miR-3142:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.96E-32 5.57E-28 2.98E-31 2.75E-30 95 632 "ACADM,ABCD2,OGT,ANK2,PKP4,CASK,NCOA1,ADAM23,ZNF599,PRC1,METTL6,ARHGEF1,LRBA,CHN2,EPS15L1,QKI,ABI3BP,CLOCK,AKAP12,VCAN,SOCS5,PDE4DIP,HDAC9,TMEM170A,WDR20,ARRDC4,DTNA,EBF1,PHF20L1,C3orf18,PAN3,RASGRP2,MRPL37,SIRPB1,EYA1,MED12L,FGF1,IP6K2,ZMYND15,JKAMP,ST6GALNAC3,STAU2,KIAA1841,SRCAP,MMADHC,PPARGC1A,COPS8,FERMT2,GPD2,GRIA2,FAM19A2,KAT7,HSF2,FAM95B1,ZFYVE27,NTRK2,NTRK3,SEMA5B,PURG,PILRA,PPM1B,PPP2R5E,PPP3CA,MAPK9,VPS13C,BDNF-AS,PTPRE,TUG1,ZNF493,TRIM68,RGS3,PBRM1,YY1AP1,ZNF671,MCMBP,ATXN7,SCN7A,CASC3,ZNF430,MYO16,LMO3,TBCEL,TCF12,SYNE1,DOCK9,RNF216P1,SYNPO2,STXBP4,CCDC14,ZNF154,UPF3A,MFF,RGS7BP,AMN1,SMIM8" MicroRNA hsa-miR-1274a:mirSVR_highEffct hsa-miR-1274a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-31 5.70E-28 3.05E-31 2.81E-30 91 583 "METAP1D,KLHL32,BEND6,TXNDC16,ADGRF5,SPTBN4,RGS20,NCOA1,N4BP2L1,NRP2,BMPR1B,SCAPER,CALB1,CS,CSNK1G3,UBXN2A,USP6NL,ZC3H11A,NR1D2,DPYSL2,PDCD6IP,PHF20L1,MBNL2,AASS,EPB41L2,DENND4A,FAM198B,ACSL4,SCML2,ZNF589,ANKFY1,OGA,ZNF274,ZNF638,PCLO,GRM8,SOX21,ARHGAP36,MIER3,AGBL5,CFAP126,SMAP1,ZNF678,NME9,KCNB1,GPR62,KCNN2,CREG2,HECTD2,AFDN,NF1,NOVA1,PDCD2,PIK3C2A,FAM216A,MTRF1L,PPM1B,PPP2R2C,PTH1R,TMEM260,ZIK1,EML5,GAL3ST4,RGS3,RIC8B,RNASEL,CARF,GSTCD,KIRREL1,ATP8B4,STK32B,ATAT1,SUPT20H,SLA,SNRPN,SPART,ATP10B,CLSTN2,NXT2,RGL1,SYPL1,SATB2,SLC44A1,NPL,ANKRD20A2,FAM155A,CELF4,STOX2,TUBA1A,FIP1L1,MARCH8" MicroRNA hsa-miR-513a-5p:PITA hsa-miR-513a-5p:PITA_TOP PITA 1.10E-31 6.12E-28 3.28E-31 3.02E-30 61 260 "CCDC85A,USP31,UNC5A,RTL9,LCORL,CDC14B,SYNJ1,CACNA1A,RUNX1T1,ZMYM4,CFL2,SOCS6,QKI,CNR1,CRY2,PPP1R16B,DPYSL2,MAMLD1,CELSR3,ERBB4,EYA1,MEX3B,AGAP2,EVL,USP21,CHL1,PPARGC1A,GRB10,C1QL4,MAP4K5,MIER3,AGFG1,KCND2,MARK1,ADAM11,CHIC1,TMOD2,PDZRN4,WBP1L,SNRK,USP47,FAM184A,ALG9,SH3GL3,PPM1E,MYCBP2,SS18,ARHGEF9,SYP,SYT1,MTCL1,KIAA0930,TRIM2,TRPS1,SSBP2,MAP3K12,EMSY,PDSS2,KAT6A,JMJD1C,RNF146" MicroRNA hsa-miR-668:mirSVR_highEffct hsa-miR-668:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-31 6.40E-28 3.42E-31 3.15E-30 79 444 "KLHL32,CCDC85A,ADD1,ABCD2,FAM131A,USP37,ARRB2,DPY19L3,DST,CALB1,CALB2,CAST,SYNGR3,CDH2,ZMYM4,RCBTB2,ARMC8,TRIM69,ARHGEF10,DZIP3,PHF14,BOC,DGKG,IP6K1,DDX46,DPP6,E2F6,EDNRB,EMX2,EPHB1,CEP78,FGFR1,ERAP1,KIAA1841,SRCAP,GHR,TOX3,GNAO1,TMEM121B,ATXN2L,SYNPO,NEGR1,GPR155,MEIS1,MT1M,MXI1,CCDC13,CNOT4,LOC100128398,PCDH9,NALCN,EXOSC10,SDK2,RNASEL,CCDC102B,CCDC112,SLA,ZFP1,SMARCD3,SNCA,SP4,CDK19,CLASP2,NECAB1,SYNE2,ZEB1,EIF4ENIF1,VGF,TRIM9,LYPD6,ZSCAN26,SMARCAD1,EMSY,DNALI1,HPS4,NAV3,SLC17A7,SMIM8,ACTR3B" MicroRNA hsa-miR-24-3p:Functional MTI Functional MTI miRTarbase 1.16E-31 6.46E-28 3.45E-31 3.18E-30 112 855 "XKR4,ADD1,PLEKHH1,ESYT2,TBC1D14,TXNDC16,TAOK1,TRMT9B,AMPD2,APAF1,CCAR2,EIF4G3,STX16,BCL7A,BMP7,ARHGEF7,NAE1,GYG2,LONRF2,ZBED1,MAGI1,AKAP7,AKAP5,TBPL1,CRY2,APPL1,GREB1,DCAF4,MATR3,YTHDC1,GUCD1,SLC29A4,HEYL,MRO,EIF5,TNK2,EPB41,IGSF6,SCML2,POLR1B,FGF11,FGFR3,AMOTL2,PCYOX1,NOP56,CINP,PDLIM5,MSANTD4,GABRB3,TRAF3IP2,SESN1,BRD8,CRCP,DBF4,GLYR1,GLUL,POLL,BVES,IRAK3,NEGR1,AGFG1,HSF2,IGF1,NKD1,KCNJ5,KLHL23,LIMS1,SAMD5,MT1M,MXI1,ZC3H12B,SLC11A2,PDPK1,STRN3,MAPK7,APTX,PEX2,HKR1,SETD5,C12orf49,ELP2,FBXW7,ZFP30,AMBRA1,R3HDM2,NUBPL,BTBD3,ZNF430,SEPHS1,ZKSCAN3,INAVA,UHRF1BP1L,DDN,ZNF621,POGZ,SS18,ZSCAN29,MMS19,ALG1,SLC19A3,ZNF106,UBC,RPL7L1,UBE3A,ZNF708,ZNF17,ZNF70,ZXDA,URM1,FBXO36,ZDHHC20,NETO2" MicroRNA hsa-miR-532-3p:mirSVR_highEffct hsa-miR-532-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-31 7.60E-28 4.06E-31 3.73E-30 94 622 "KCNH8,AP2A2,KIAA1324,ALCAM,VAT1L,PLA2G4C,EIF4G3,ALDH7A1,CALB1,CAMK2G,CLDN10,LDB2,CDH2,HECTD1,FAM149A,SUMF2,SEC31B,SEC24C,ERC2,KATNAL2,IST1,SNAP91,CHRDL1,NYAP1,DOCK2,RCAN1,AASDH,PHC2,KLHL5,CELSR3,PHF20L1,APH1A,KMT5B,SPEG,SLC9B2,FER,FOXF2,ATP6V1H,CELF1,RAPGEF6,NEU3,TUBGCP4,CBX1,ADGRA3,PLCD4,CFAP126,C2orf72,ZIC5,SMAD9,MBD1,MBNL1,MIA2,PPM1L,ZNF680,NEK1,P2RY1,PDE4D,GNG2,NLGN3,XRN1,PURG,IRX1,PPP2R5E,PRKACB,PSD,FAM66C,ZCWPW1,CRTAC1,RGS12,CARF,RYR3,AMBRA1,CNKSR2,ABLIM3,SLA,PEG10,SEPT8,COBL,ANKRD12,ZFP90,SZT2,USP32P1,ITGB3BP,TMPO,SYNPO2,RPRM,SPIRE1,UPF3A,ADAMTS9,PPP1R3F,KCNAB1,PDSS2,MSRB3,FAM198A" MicroRNA hsa-miR-582-5p:TargetScan hsa-miR-582-5p TargetScan 1.52E-31 8.53E-28 4.55E-31 4.19E-30 80 457 "BEND6,APC,LGR5,RASL11B,MTMR2,LDLRAD4,DGKI,CDH2,KCNAB3,CACNA2D2,NRXN3,FAM171B,CREM,HAPLN1,ANKRD44,CTH,GREB1,PYGO1,JAKMIP2,RAB39B,DMD,EIF4G2,RGS17,C8orf37,MTSS1L,ETV1,MRVI1,MEX3B,GPR34,HMGCR,HNF4G,JAK2,KCNB1,GPR62,KCNN3,KCNQ3,KPNA5,PAXBP1,MARK1,MEIS1,MITF,MSI1,NCAM2,NOVA1,PDE4A,PDE4D,PFKFB2,GPSM2,PURG,SCHIP1,PRKACB,PTPRG,GTDC1,ROBO2,SATB1,AMBRA1,FBXO11,FAM81A,CXXC4,KIF13A,KDM3A,NFASC,LARP4,NUDT10,NSD1,AP4E1,NACC2,CSMD1,KAT6B,RASD2,RICTOR,KCNK12,DPYSL5,FZD3,RTN4,HNRNPA3,MSRB3,FRMD6,GAN,PRRT4" MicroRNA hsa-miR-202*:mirSVR_highEffct hsa-miR-202*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-31 8.99E-28 4.79E-31 4.41E-30 103 738 "ABCF1,ACTN1,KDM5D,KLHL32,ADD2,C1QTNF3,AMPD3,OGT,PKP4,EPB41L5,LRBA,C4orf33,CNR1,IQCK,SLC4A8,RTTN,GDA,CS,SNCAIP,ARHGEF10,PHF14,ARHGAP24,DGKB,BRINP1,DDX46,ALKBH8,SGSM2,E2F6,SEMA3D,FAM13A,KMT5B,GOLGA7,CALCRL,PAN3,ACSL4,CEP78,SLC9B2,FGF12,IQCG,PSD2,STAU2,GAD1,GDF9,ADAM28,TNRC6A,TDRKH,ATP2B1-AS1,MAP4K5,AGBL5,ZDHHC15,HSF2,ZNF181,MATN2,MITF,AFDN,COL28A1,ZNF92,NEK1,SMIM11A,PCSK5,PDCD2,MINDY2,CEP41,SNRK,TMEM260,C1orf109,TTC13,ZNF493,ZFHX4,ADAL,ATXN7,STUM,CCDC88A,PDZD2,KDM3A,KDM4C,RBM26,NFASC,TROVE2,ZNF302,NKAIN2,ERBIN,NEK4,ZC3H4,VPS13A,TBCEL,ZEB1,TCF12,TEK,NR2E1,SYNPO2,RUNDC3B,AMACR,RPL7L1,MICU3,TRIM9,LYPD6,STOX2,ADAMTS9,FIP1L1,FAM13C,FZD3,IFT88" MicroRNA hsa-miR-1200:PITA hsa-miR-1200:PITA_TOP PITA 1.74E-31 9.74E-28 5.19E-31 4.78E-30 70 350 "PWWP2A,HECW2,OSBPL8,ZNF687,DOCK11,BCL7A,ARHGEF7,MTMR3,CALM1,LDB2,L3MBTL4,IGDCC3,PLCXD3,ZFYVE16,TM9SF4,PITPNC1,FAM107B,ARRDC4,PHC2,FAM13A,PAN3,EPB41,NRN1,SRRM4,PCDH17,TTBK1,TNRC6A,KDM2B,LOXL3,PCLO,KAT7,LINGO1,BACH2,DHX35,SLC35G1,L1CAM,MARK1,CHIC1,MIA2,MYT1,SLC11A2,KSR2,PDE4B,PDE4D,ANKRD16,CNNM2,PTK2,FIGN,ZFHX4,ALG9,SMPD3,KIF21A,PPM1E,KIF16B,AMBRA1,FBXO11,FAM81A,FAM214B,SOX11,GLT8D1,MYCBP2,ZSCAN29,STAC2,SYP,CAMTA1,RPGRIP1L,DOCK9,TMEM121,AP4E1,RELL2" MicroRNA hsa-miR-363*:mirSVR_highEffct hsa-miR-363*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-31 9.81E-28 5.23E-31 4.81E-30 94 624 "RALGAPA1,CCDC85A,BEND6,OSBPL1A,ADGRF5,SEMA6A,PCDH10,FAM135A,PHF12,FAM131A,PHYHD1,CHID1,MPDZ,NRP2,CACNA1B,LURAP1,KALRN,CAST,AP4M1,ZMYM4,DLGAP1,CCPG1,CPS1,SH2B1,LRRC3B,PDE4DIP,RASGEF1C,HDAC9,TM9SF4,DBN1,ARMCX2,ELMO1,HS3ST2,ACOT8,DTNA,MAMLD1,EBF1,EDNRA,EGFR,TNK2,EPHB1,ABCA8,ACSL4,DLC1,ZMYND10,FER,FGF12,AMOTL2,POLK,NELFCD,ERAP1,ZNF559,LYVE1,MCHR1,PCLO,DIDO1,ZNF496,LRRC25,ZNF678,CAMK2N2,MBNL1,CCDC13,NPY,NOVA2,ZNF827,CNNM2,CCDC40,RAP1GDS1,EXD2,C12orf49,CCDC25,TCP11L1,FNIP1,TET1,KIF13A,KDM4C,PBLD,TROVE2,SYNE2,SYN1,SMG6,SYNE1,USP32P1,HIF3A,SIK3,PRRT1,TPM2,ELP5,EMSY,MFF,CIAPIN1,SIGLEC10,RNF170,PRRT4" MicroRNA hsa-miR-193a-3p:mirSVR_highEffct hsa-miR-193a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.98E-31 1.11E-27 5.90E-31 5.43E-30 81 470 "KCTD16,RTL9,HACE1,ALCAM,UPRT,STX16,CALB1,THSD7A,CALM1,SPAG9,RUNX1T1,USP6,PLAA,TPP1,COL4A5,EARS2,GIT2,ZC3H11A,E2F6,IRAK4,RABEPK,HVCN1,ST6GALNAC3,RAPGEF6,DISC1,ARFIP1,PPARGC1A,RAB30,CBX1,GNAO1,GPR12,ADAMTS13,AGBL5,ZNF181,LAMP2,STMN1,LIMS1,MYCN,NF1,NOVA1,GPR137C,PDCD2,CEP41,MAPK10,DEF8,CNTLN,FAT4,MSANTD2,MORC4,CARF,GLDN,LRRK2,SCP2,CCDC88A,ELMO2,SNRPN,SPATA7,BDP1,SP4,ERBIN,ST5,SULF2,SEPT3,SLC37A2,C12orf76,CAMTA1,AGTPBP1,DMXL2,RPGRIP1L,USP32P1,R3HDM1,C9orf85,SMUG1,RUSC1,PLEKHH2,CCDC14,LINC02210,NELFE,ADAMTSL3,IFT88,RNF146" MicroRNA "CAGTGTT,MIR-200A:MSigDB" "CAGTGTT,MIR-200A:MSigDB" MSigDB 2.02E-31 1.13E-27 6.01E-31 5.53E-30 64 291 "SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,ATP2A2,NRP2,JAZF1,GPC2,KALRN,SPAG9,SEPT7,EVI5L,FOXN3,PPT2,QKI,CNR1,MYRIP,CDC42BPB,CSNK1G3,KIAA0408,HDAC4,TM9SF4,SNAP91,GRIN3A,YAF2,DLC1,OLFM1,ANKFY1,TCERG1,HLF,ACOT7,STXBP5,TTYH2,MBNL1,MMP16,PCDH8,PCDH9,TRHDE,PRKACB,PTPRG,KHDRBS2,ATAT1,ATXN7,SCN2B,PPM1E,CHD9,MBD5,SOX11,SP4,NMNAT2,NFASC,CLASP2,TTBK2,STXBP1,TCF12,SIRT1,LRRC8A,NR2C2,TSC1,UBE3A,FRMD6" MicroRNA "CAGTGTT,MIR-141:MSigDB" "CAGTGTT,MIR-141:MSigDB" MSigDB 2.02E-31 1.13E-27 6.01E-31 5.53E-30 64 291 "SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,ATP2A2,NRP2,JAZF1,GPC2,KALRN,SPAG9,SEPT7,EVI5L,FOXN3,PPT2,QKI,CNR1,MYRIP,CDC42BPB,CSNK1G3,KIAA0408,HDAC4,TM9SF4,SNAP91,GRIN3A,YAF2,DLC1,OLFM1,ANKFY1,TCERG1,HLF,ACOT7,STXBP5,TTYH2,MBNL1,MMP16,PCDH8,PCDH9,TRHDE,PRKACB,PTPRG,KHDRBS2,ATAT1,ATXN7,SCN2B,PPM1E,CHD9,MBD5,SOX11,SP4,NMNAT2,NFASC,CLASP2,TTBK2,STXBP1,TCF12,SIRT1,LRRC8A,NR2C2,TSC1,UBE3A,FRMD6" MicroRNA hsa-miR-138:PITA hsa-miR-138:PITA_TOP PITA 2.18E-31 1.22E-27 6.48E-31 5.97E-30 61 263 "SYS1,UNC5A,SEMA6A,JAZF1,USP6,CNOT8,ZNF385A,SLC35F1,SNCAIP,SOCS5,MAML1,ARMCX2,MYEF2,DNAJB6,CELSR3,KMT5B,RCAN2,CLVS1,ST3GAL6,NBEA,SRRM4,GGT7,PPARGC1A,FERMT2,PCLO,CIT,MIER3,SLC6A17,KCNK3,MSI1,NEXMIF,NFIX,NPTX1,PDE3A,GPR85,GNG2,EPB41L4B,VSTM2L,RELN,PTK2,USP47,MSANTD2,KBTBD4,CPEB4,RCOR3,ERC1,SPTB,CDK19,SEPT8,KANK1,SULF2,NSFL1C,ADGRL3,TBL1X,TCF4,KIAA0930,SIRT1,TRPS1,ZIC1,SLC17A7,JMJD1C" MicroRNA hsa-miR-4321:mirSVR_lowEffct hsa-miR-4321:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.22E-31 1.24E-27 6.60E-31 6.07E-30 57 227 "FMNL2,ZFAT,APBB2,PCDHGB4,ATP2A2,ADGRB3,RGS9,KSR1,RUNX1T1,ARHGEF10,HDAC9,DAPK1,PITPNC1,POM121,SPOCK3,EIF1,SYNCRIP,EFCAB2,GABRG2,RAB30,LRRC75A,SCIN,ITGAM,KCNQ3,PAXBP1,MAN2A2,SRSF12,NOVA1,DNHD1,PCDHGC3,PRKACB,SLC25A48,SH3TC2,KCTD17,ATXN2,SHMT2,IFT122,USP33,UNC5B,TSPYL2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,KAT6B,TRIO,UBE2H,XRCC4,EML6,NLRP3" MicroRNA hsa-miR-105*:mirSVR_lowEffct hsa-miR-105*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.46E-31 1.38E-27 7.32E-31 6.74E-30 84 506 "KDM5D,ELFN2,SPOP,AMPD2,APLP1,GPR146,CFLAR,BMPR1B,ARHGEF7,CALB1,CAST,CD38,ARHGEF2,LRRFIP1,ABI3BP,NRG2,CREM,CSNK1G3,CYBB,KATNAL2,LIN54,DAPK1,SCRN1,DDX46,ALKBH8,DPH1,DPP6,ABCC5,EDNRB,MBNL2,EIF1,FCGR1B,HRASLS5,TUBGCP4,SRCAP,ARFIP1,GFER,GRM2,PACSIN2,KCNN2,SMAD1,SHC3,ADAM22,NEK1,PDPK1,PDZRN4,PMP22,PPARA,GRAMD1C,DEF8,TMEM260,PTPRB,PTPRE,RIC8B,CARF,ROBO2,MAP6D1,RXRA,SATB1,ATXN2,CHD9,R3HDM2,NLGN1,KDM4D,NAPB,ANKRD36,FNBP1,ZNF423,SYN1,MLST8,ADGRL3,MGRN1,ERCC6L2,TSN,SGK3,FAM155A,UGT8,CCDC14,GUSBP1,ZNF23,MKRN3,EML6,ADAMTS9,URM1" MicroRNA hsa-miR-4283:mirSVR_highEffct hsa-miR-4283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-31 1.41E-27 7.51E-31 6.91E-30 70 352 "ASPHD1,ACHE,BRAP,MTUS1,CC2D2A,USP35,AMPD2,OGT,FGD2,LCORL,MADD,ADAM15,CASTOR3,KALRN,RUNX1T1,ENTPD6,DGKI,ANKRD44,CLIP3,CSNK1E,VAC14-AS1,EARS2,DNM1,SLC25A18,EBF1,FCF1,EGFR,F5,SPSB4,IP6K2,FLT1,TMEM8B,SIGLEC8,LRRC37A6P,AHDC1,TNRC6A,GLUL,GPD2,CFAP126,ITPKB,MATN2,MEIS2,MX1,DNHD1,PLXNB1,PILRA,PSD,MSANTD2,FIGN,CARF,NEK11,ST6GALNAC6,ASAP3,ANKRD36,SNRPN,MYO16,NFASC,SEPT3,SYN1,SYT1,TAL1,RNF216P1,DICER1-AS1,MTMR14,OSBP2,WIPF1,PCBP1-AS1,SMIM8,CASC15,MSRB3" MicroRNA hsa-miR-7-5p:TargetScan hsa-miR-7-5p TargetScan 2.57E-31 1.44E-27 7.64E-31 7.04E-30 75 405 "ELFN2,ADD2,RNF150,HECW2,OGT,PPFIA3,ARRB1,RASL11B,ATP2B2,KSR1,CACNB4,HAP1,DLGAP2,FOXN3,CNOT8,IGLON5,CNN3,CRY2,NCOR1,CLIP3,FAM131B,CPEB2,DPYSL2,EGFR,EGR3,ERBB4,MED12L,HPCAL4,ANKFY1,GABBR1,GGT7,BTN2A1,COQ10A,NKD1,CDH20,KCNB1,MAP4,ADAM11,NOVA2,CHAMP1,PAX6,PDE4A,PDE4B,PDE4D,CCSER2,PLEC,MAPKAP1,POU6F1,PKIA,PRKCB,MAPK4,MAPK10,OXR1,ALG9,SATB1,ATXN7,SCN2B,KIF16B,AMBRA1,KIF13A,FAM126B,CLASP2,NXT2,NECAB1,PLCB1,ANKRD28,ANKRD12,FAM208A,PPIL6,FLRT2,RBFOX3,GAL3ST3,RGS7BP,RSPRY1,FXR1" MicroRNA "GTGCCAA,MIR-96:MSigDB" "GTGCCAA,MIR-96:MSigDB" MSigDB 2.83E-31 1.59E-27 8.40E-31 7.73E-30 63 283 "XKR4,ADCY6,KCTD16,SEMA6A,ALK,OGT,LRCH2,VAT1L,DPY19L3,ADGRB3,JAZF1,LDLRAD4,CACNB4,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,CNN3,CABP1,COL9A1,MYRIP,CDC42BPB,CSF1,LRIG1,RIMS4,HDAC9,ARHGAP24,TM9SF4,PLPPR4,E2F5,PHF20L1,EIF5,FOXF2,FAM49B,FYN,B4GALNT1,ZHX1,BACH2,LAMP2,MITF,NOVA1,NPTX2,EPB41L4B,SH3KBP1,RIC8B,ZFHX4,FAM81A,BTBD3,CPEB4,KLHL7,COBL,TACC1,CAMTA1,FBXW11,TBL1X,TPM1,RICTOR,ZIC2,TMEM198,ST7,JMJD1C,GAN" MicroRNA "ACATTCC,MIR-1:MSigDB" "ACATTCC,MIR-1:MSigDB" MSigDB 2.83E-31 1.59E-27 8.40E-31 7.73E-30 63 283 "OGT,MAP4K3,BCL7A,SYNJ2,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREM,AKAP12,RIMS4,HDAC4,MATR3,DGKG,PLPPR4,DMPK,E2F5,EDN1,PHC2,CELSR3,RCAN2,FGF14,IP6K2,SLC37A3,PDLIM5,CPLX2,KDM2B,ADGRA3,GPD2,TPPP,RNF165,BACH2,HMGCR,SMAP1,IGF1,KTN1,MEIS1,GIT1,ZNF827,TMOD2,WBP1L,PTPRG,PBRM1,FBXW7,SEMA6D,TRA2B,FNDC3A,SMARCA4,SNAP25,MAPKBP1,TMCC1,USP33,SP2,SS18,TRIM2,PUM2,SLC44A1,LRRC8A,UBE2H,TBC1D15,RICTOR" MicroRNA "ACATTCC,MIR-206:MSigDB" "ACATTCC,MIR-206:MSigDB" MSigDB 2.83E-31 1.59E-27 8.40E-31 7.73E-30 63 283 "OGT,MAP4K3,BCL7A,SYNJ2,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREM,AKAP12,RIMS4,HDAC4,MATR3,DGKG,PLPPR4,DMPK,E2F5,EDN1,PHC2,CELSR3,RCAN2,FGF14,IP6K2,SLC37A3,PDLIM5,CPLX2,KDM2B,ADGRA3,GPD2,TPPP,RNF165,BACH2,HMGCR,SMAP1,IGF1,KTN1,MEIS1,GIT1,ZNF827,TMOD2,WBP1L,PTPRG,PBRM1,FBXW7,SEMA6D,TRA2B,FNDC3A,SMARCA4,SNAP25,MAPKBP1,TMCC1,USP33,SP2,SS18,TRIM2,PUM2,SLC44A1,LRRC8A,UBE2H,TBC1D15,RICTOR" MicroRNA hsa-miR-1470:mirSVR_lowEffct hsa-miR-1470:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.84E-31 1.59E-27 8.42E-31 7.75E-30 80 461 "ACADM,NCKAP5,ADORA1,SPOP,MYOM1,BCL7A,BTK,GYG2,LARGE1,MAGI1,MYL6B,SULT4A1,SEC31B,NCOR1,PHF14,DAPK1,LYPD1,KIF19,DLX1,DNM1,USP3,TOM1,APH1A,EGFR,ING4,C3orf18,EMX2,EPB41,SUCO,FLT1,TMEM107,CGREF1,STMN2,DIDO1,C1QL4,ADAMTS13,BVES,RASSF8,NXPH3,AGBL5,KCNB1,ADAM11,LRP1B,SCAMP5,MYO7A,NTRK2,PDE3A,PDE4A,ZFYVE21,SH3KBP1,BCAS3,WBP1L,PTPRH,FAT4,RIC8B,S100B,SCN8A,FOXRED1,ARFGAP1,RCOR3,MBD5,FAM219A,ZSWIM8,SPTB,ITPRID2,SSPO,ADGRL3,NSD1,TNS2,PIK3R5,UBE2H,USP1,WIPF1,GUSBP1,XRCC4,PRTFDC1,SEMA3B,UBE3B,PHTF2,FXR1" MicroRNA hsa-miR-3155:mirSVR_highEffct hsa-miR-3155:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-31 1.68E-27 8.89E-31 8.18E-30 97 666 "DGCR6,ACHE,C3orf14,NDRG3,PCDH19,TXNDC16,CC2D2A,ARSE,CAST,MAGI1,SRSF11,SEC31B,CREM,ANKRD44,SNCAIP,CSF1,FAM169A,RIMS2,DCAF4,RIPOR2,RHOBTB1,SV2B,DPYSL2,EDNRB,SEMA3D,EIF4G2,STARD3NL,EPHB1,ETV1,EXTL2,FDFT1,FGF1,SPSB4,FHL1,POLK,SARAF,AP4B1,ABLIM2,FAM120B,COPS8,CLASRP,RNF165,MAP4K5,PADI2,SCIN,IL6R,KCND1,HECTD2,MAP2,MBD1,MOV10,PTOV1,SLC11A2,GLIPR1L2,RETREG1,SMIM7,ING3,MAPK10,GRAMD1C,SAMD9,APTX,BDNF-AS,TMEM260,PTPRE,ZMAT4,TRIM68,REV3L,GTDC1,SNX22,NEK11,GLDN,ABCA11P,SCP2,TNFRSF19,ARX,ZNF667,SNRPN,MYCBP2,KDM4C,CDK19,ST5,TACR1,TBCEL,TBL1X,GPRIN3,FRYL,CYB561A3,ENHO,TK2,TPM1,NPL,LGI4,PROCA1,UPF3A,STOX2,GAL3ST3,PPP1R3F" MicroRNA hsa-miR-134:mirSVR_highEffct hsa-miR-134:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.21E-31 1.80E-27 9.50E-31 8.75E-30 100 705 "KCNH8,WDR35,AMPH,AMT,SUGT1P4-STRA6LP-CCDC180,EPB41L5,NUMB,ATP6V0A1,BACH1,MPDZ,MTMR2,CARS,RUNX1T1,SLC16A4,P2RX6,MAGI1,CHN2,FAM19A5,MAP4K4,ARHGEF6,CPS1,FAM171B,ANKRD44,SNCAIP,KIAA0040,ARMCX2,DNAH9,PDCD6IP,EDN1,EGFR,EIF1,VPS13B,EXTL2,TAOK3,ZNF605,DOT1L,GABBR1,ERAP1,MSTN,CBX1,GNAL,GNAO1,MCHR1,HAS2,HNMT,KCNQ3,KPNA5,MAT2A,MBNL1,LRP1B,MMP16,NFE2L2,NRCAM,NTRK2,LOC100128398,ETFRF1,PIK3C2A,XRN1,PLCB2,CEP41,PTPRB,SUSD4,CRTAC1,ELP2,PCMTD2,RPL15,ADAL,ZNF354C,TNFRSF19,CCDC92,SLA,SLC14A1,GKAP1,ZNF415,SNRPN,ZNF423,SPTAN1,NFASC,CLSTN2,KANK1,VPS13A,NSD1,SIK3,ZFPM2,TMEM9,KAT6B,PPIL6,SSBP2,ZKSCAN5,WIPF1,ZNF711,ZNF28,TRIM9,MKRN3,FSTL5,SLC30A4,MFF,CADM2,TRAM2-AS1,KLHDC1" MicroRNA hsa-miR-3941:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-31 2.04E-27 1.08E-30 9.93E-30 77 429 "ESYT2,TAOK1,ATP2A2,BACH1,CA8,TBRG4,CFL2,B4GALT6,TBPL1,BAG4,ANKRD44,MYADM,SPOCK2,DBT,KLHL3,SV2B,EGR3,EIF5,C8orf37,TUBD1,CHST15,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,DIDO1,PARD3B,CACFD1,HLF,ZIC5,SCIN,IL6ST,ZNF678,KCNB1,KLHL23,SFXN5,SYTL4,NEXMIF,TMOD2,PIK3R1,PPP2R5E,SNRK,RDX,ZMAT4,C12orf49,STX1B,SBF1,CSRNP3,SLC12A2,SLC22A4,ZFP1,KIF13A,ZNF415,FAM126B,UNC5B,SS18,NECAB1,GPRIN3,SIK3,SLC44A1,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,NDRG4,CRB2,ZXDA,ADAMTS9,WNK3,FAM198A,SPATA13" MicroRNA hsa-miR-486-3p:mirSVR_highEffct hsa-miR-486-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.02E-31 2.25E-27 1.19E-30 1.09E-29 99 694 "ABHD6,KIAA1211,ADRA1D,OLMALINC,SPOP,LTBP4,AMPD2,OGT,KCNAB2,PHYHD1,ARRB2,ATP1A3,BTK,CACNA1G,CACNA1B,VXN,LRBA,CHN2,CNGA3,CNTFR,CLIP3,CS,SEC24C,CST3,HDAC9,DCAF8,PITPNC1,DDX46,CPEB2,EIF1,RAB9B,ERBB2,ZSCAN30,PPP1R1B,SPSB4,BAIAP2,FLNC,C2orf88,TMEM175,PDLIM5,MEGF11,IGSF5,POLL,DIDO1,ATE1,GRM2,NXPH3,IDH3A,KHK,KIF5A,STXBP5,MBD1,MOV10,MSR1,TAGLN3,MXI1,RTL5,NEFH,NME4,DNHD1,OGG1,CDK18,PDCD2,SEMA5B,EPB41L4B,SH3KBP1,PKIA,APTX,PTPRN,KIRREL1,MRAP2,RPE,BAALC,STK32B,COPZ1,FNDC3A,ZSCAN29,ADHFE1,PHLDB1,SEPT3,NUDT10,PLCB1,DNMBP,TAL1,TCF12,DOCK9,OBSL1,THRA,TIAM1,SSBP2,RPRM,PLPPR2,LYPD6,ZNF142,DNALI1,ADAMTS9,TMEM178A,HPS4,SLC17A7" MicroRNA "TATTATA,MIR-374:MSigDB" "TATTATA,MIR-374:MSigDB" MSigDB 4.29E-31 2.40E-27 1.27E-30 1.17E-29 61 266 "ABR,ACTN1,PCDH10,FAM135A,MAP4K3,NCOA1,NUMB,TMEM108,ATP1A1,LDLRAD4,NOG,NUMBL,QKI,HECTD1,HAPLN1,PLPPR4,WDR20,DMD,MBNL2,EIF4G2,DENND4A,EYA1,ABCA8,MED12L,UBE2E3,MEX3B,PPARGC1A,TCERG1,TNRC6A,STMN2,HLF,MAP2,LRP1B,MEIS1,AFF1,NFIX,NOVA1,NPTX2,OCRL,PDE4B,PDE4D,PDPK1,PPP2R2C,PKIA,RORB,SCN2B,SYBU,NLGN1,ARHGEF40,CPEB4,SP4,ZNF423,IQSEC2,SYT1,ATMIN,TCF12,SYNE1,UBE2H,SMARCAD1,SOCS4,ST8SIA2" MicroRNA hsa-miR-1254:mirSVR_highEffct hsa-miR-1254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.47E-31 3.62E-27 1.91E-30 1.76E-29 100 711 "CLK4,EMILIN3,MTUS1,C1QTNF3,PHF12,ZFYVE28,MARCH3,SLC4A4,ZNF582,SLC2A11,KSR1,KALRN,USP6,LARGE1,CNOT8,PPT2,C4orf33,SRP14-AS1,LETMD1,AHCTF1,CLIP3,CS,RGS6,SEC24C,FAM169A,RASSF2,SV2B,RPS6KL1,DOCK2,DMTF1,SUGP2,KMT5B,TMEM132E,EPHB1,ERBB2,TUBB3,POLR1B,FGF11,FGF13,FGFR1,TMEM107,SMC2,MSANTD4,MPP6,FYN,SRCAP,PPARGC1A,RUNDC3A,TOX3,ADGRA3,GPD2,GRIN2C,AGBL5,CPT1C,IRF8,NKD1,NME9,CYP27C1,AQP11,PPM1L,GIT1,MYO5A,NF1,NOVA1,DNHD1,NRCAM,ZNF713,PDE3A,PFKFB2,SNX10,PCDH18,MAPKAP1,ING3,SEPT4,PIGG,NWD1,ZNF493,RASGRF2,KIF7,TCP11L1,CLIP1,HES6,KIF27,ZFP30,SMARCD3,SNRPN,HECW1,RBM26,ERBIN,ADHFE1,CUX2,SYNE1,FRYL,CHST8,MTMR14,TSC1,PLEKHH2,VSNL1,FSTL5,CADM2" MicroRNA hsa-miR-183-5p.1:TargetScan hsa-miR-183-5p.1 TargetScan 6.98E-31 3.90E-27 2.06E-30 1.90E-29 71 368 "RNF157,OSBPL8,PKP4,NRP2,RUNX1T1,NRXN3,CLCN3,QKI,AKAP12,CSNK1G3,PLXNA4,FAM169A,PLCXD3,DOCK4,LIN54,KLHL3,RHOBTB1,SACS,CPEB2,DTNA,CELSR3,GOLGA7,RGS17,MRVI1,MED12L,PCYOX1,ATP2C1,CELF1,RAB30,KDM2B,MAP7D2,PRUNE2,PRDM5,BVES,MAP4K5,FRMD5,BACH2,HLF,ICA1,KLHL23,KIF2A,HECTD2,LSAMP,MBNL1,LRP1B,MEF2C,P2RY1,PDE3A,PDE4D,KCTD15,PRKACB,MAPK4,PTCH1,CEP97,KHDRBS2,RFX3,ROBO2,SCP2,PPM1E,PKNOX2,KIF13A,ARHGAP26,LMO3,DIP2A,KANK1,RIMBP2,CSMD1,EVI5,FRMD6,RNF146,GAN" MicroRNA hsa-miR-1228*:mirSVR_lowEffct hsa-miR-1228*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.82E-31 4.37E-27 2.31E-30 2.12E-29 84 514 "ACHE,KLHL32,KIAA1211,KIAA1324,AMPD2,SEMA7A,PPFIA4,SUGT1P4-STRA6LP-CCDC180,ASGR1,GPC2,USP2,ARHGEF1,CBFA2T2,SYNGR3,ASIC3,NRXN3,AKAP7,SUMF2,SLC35F1,SNCAIP,HDAC4,SEC16A,DMPK,DPH1,ELN,SCML2,RACK1,FGF1,BAIAP2,PRKAG2,POLK,RGPD5,FYN,LRRC37A6P,CPLX1,NTNG2,STARD3,ADAMTS13,GRIN2D,LINC01089,FRMD5,FAM95B1,SOWAHA,ZNF678,KHK,IPO5,IGSF11,LOC100128398,ZNF713,PKD1,ZFYVE21,MBOAT7,VSTM2L,BCAS3,RGS3,RGS12,PRIMA1,KCTD17,TMLHE,YY1AP1,RPL15,KCNIP1,NCBP3,SEMA6D,AMBRA1,LIMS2,LGI3,SNRPN,ZSWIM8,ZC4H2,SSPO,SLC37A2,MLST8,NEU4,TPCN2,RELL2,PDSS1,LMF1,CLIP2,ATP6V0E2,PCBP4,RTN4,CASC15,FAM219B" MicroRNA hsa-miR-378:mirSVR_highEffct hsa-miR-378:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.90E-31 4.42E-27 2.33E-30 2.14E-29 106 792 "ARHGAP20,FAM135A,OGT,DDO,PLA2G4C,EIF4G3,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,TIGD7,COPB2,PPT2,C4orf33,RAB26,AHCTF1,ZFP28,CDC42BPB,CREM,ARHGEF10,PHF14,USP6NL,CCDC144A,RIPOR2,DCAF8,DDX46,GRIN3A,DOCK2,EBF1,WDPCP,HIPK3,CELSR3,KMT5B,ENPP6,SPEG,FCGR1A,CEP78,FCGR3A,FGF12,TMEM164,ATP5PD,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRG2,ERAP1,GPT2,TDRKH,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,MAN1B1,SMAP1,MYLK2,IL6ST,KIF2A,MARK1,LYRM9,NDP,NEK1,NF1,NFE2L2,CHAMP1,LOC100128398,TRHDE,PRKACB,PRPSAP2,DCHS2,SNRK,PTPRD,USP47,RGS4,ELP2,FBXW7,BAALC,KCNIP1,ATF7IP,MBD5,IQSEC2,NEK4,DIP2A,PLCB1,CAMTA1,AGTPBP1,DMXL2,FRYL,ZFPM2,AP4E1,PPIL6,GUSBP1,TRIM9,EML6,ZNF189,CADM2,PRTFDC1,EPM2A,ST7" MicroRNA hsa-miR-186-5p:Functional MTI Functional MTI miRTarbase 8.78E-31 4.91E-27 2.59E-30 2.38E-29 103 753 "CC2D2A,PCDH10,TRMT9B,APC,ARRB1,ATP1B3,ATP2A2,ZNF583,LDHD,ST3GAL5,CAMK2B,CBR1,LRRFIP1,SRSF11,AHCTF1,ZNF385A,AKAP12,RIMS4,PUM1,MATR3,DBN1,FBXL5,MTX3,FEM1B,EEF1D,FRY,GOLGA7,EIF4G2,EIF5,EIF1,VPS13B,MTSS1L,DNAJC27,KATNAL1,NSRP1,ACSL4,DLC1,RACK1,SEC24B,POLR1B,UBE2E3,SPECC1,MSANTD4,MTHFD2,SEPT9,USP19,MSL3,GLUL,CBX1,GRIK5,GUCY1B1,MIER3,ZIC5,RBPJ,ITPKB,METTL21A,KIT,SMAD1,MAT2A,CNOT4,P2RX7,ABCB1,KCTD15,ZNF426,PURG,PSAT1,RETREG2,PPM1B,PRKAB2,VPS13C,QRICH1,PIGG,BDNF-AS,PTPN13,ZNF793,BEND5,ERI2,FIGN,FAM192A,FNIP1,KIF21A,SHMT2,AMBRA1,SMARCC2,BDP1,PEG10,SEPT8,SIN3B,ZFP90,TRIM2,NSD1,SLC44A1,RPL7L1,PLEKHH2,AMZ1,DPYSL5,PROCA1,SPIRE1,SLC30A4,MFF,STOX2,PHTF2,RNF146" MicroRNA hsa-miR-505:PITA hsa-miR-505:PITA_TOP PITA 9.88E-31 5.53E-27 2.91E-30 2.68E-29 58 242 "ARHGEF7,CACNB4,USP6,C1orf52,SRSF11,FOXN3,CLTB,QKI,MYRIP,CRY2,ERC2,KIAA0408,DOCK4,SPOCK3,CPEB2,E2F5,EYA1,PRKAG2,CELF1,GABRG2,CYP46A1,PPARGC1A,SPIN1,GNAO1,GRB10,ADAMTS6,KIT,LRP1B,MEIS1,MEIS2,MYCN,NEXMIF,HNRNPM,NDP,NOVA1,NPTX1,PMP22,LRP12,SCHIP1,RETREG2,MINDY2,SNRK,PTK2,USP47,SETD5,KIF21A,WDR37,EPN2,SP4,ELOVL4,SEPT3,KLHL7,ADGRL3,TRIM2,PUM2,TRPS1,REEP1,SLC38A1" MicroRNA hsa-miR-1277:mirSVR_lowEffct hsa-miR-1277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-30 5.76E-27 3.03E-30 2.79E-29 79 458 "DGCR6,AXIN2,SLC24A4,LGR5,ATP2A2,CASTOR3,CACNA1G,ZBED1,SRSF11,TAOK2,NRXN3,SULT4A1,AKAP6,LETMD1,MYRIP,ZFP28,C2CD2,CNTNAP2,KIAA0040,DAPK1,ZBTB24,HEPH,CHRDL1,EXOG,DRP2,MAMLD1,EIF4G2,FAM198B,TBC1D16,POLK,MEX3B,PCYOX1,GABRA3,MMADHC,TOX3,GRB10,LRRCC1,INSM1,IPO5,STMN1,PTOV1,MYO5A,P2RY13,OLA1,ZDHHC8,ZNF655,SLC25A23,PCDH18,MTRF1L,PDZRN4,CNTLN,PTPRB,FAT4,SLC25A36,RIC8B,RPL15,GALNT10,SUPT20H,MAST1,VPS13A,RPGRIP1L,GPR161,TP53BP2,RGMB,VLDLR,WIPF1,P2RY12,ZNF17,ZNF24,FSTL5,EML6,ZFAND5,SMARCAD1,PRDM8,ADAMTS9,FAM47E,HNRNPA3,PHTF2,FRMD6" MicroRNA hsa-miR-765:Functional MTI Functional MTI miRTarbase 1.18E-30 6.62E-27 3.48E-30 3.20E-29 69 350 "ADD2,CASKIN1,SORCS2,PHF12,PRX,ARHGDIA,ARRB1,CBS,METTL6,TMEM184B,LETMD1,CRMP1,CS,CSF1,RGS6,SLITRK5,HEYL,EIF4G1,ING4,CELF1,BRSK1,SRCAP,STARD3,PRRC2B,GRIN2D,ZBTB45,LINGO1,NEGR1,KCND1,KCNH2,KIF5A,MAT2A,NBL1,NFIX,NTRK3,KSR2,PDE4A,PFKFB3,PKM,SMIM7,PLXNB1,POLG,POLR2F,PPP2R2B,CNNM2,TMEM231,IQSEC3,HES6,TRIM67,SOX11,SP2,UNC5B,PEG10,DBNDD2,CAMTA2,ASTN2,USP22,THRA,WBP2,WRN,ZNF17,ZNF70,INTS3,CIAPIN1,URM1,ITM2C,PARP11,TMEM63C,ACTR3B" MicroRNA hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA_TOP PITA 1.26E-30 7.03E-27 3.70E-30 3.40E-29 68 340 "PCDH19,HACE1,APBA2,SYNJ1,FUBP1,JAZF1,DGKI,MAGI1,CFL2,B4GALT6,QKI,PCYT1B,CS,SLITRK5,ERC2,RIMS2,MBNL2,PCOLCE2,PAN3,ERBB4,FGF12,ATP6V1H,FUT9,PCDH17,RNF165,HAS2,KCND2,KTN1,MAN2A2,MBNL1,LRP1B,MEF2C,KITLG,MN1,NEXMIF,NFIX,XRN1,SMOX,PLXNB1,DRAM2,PPP2R5E,MTMR10,PTPRG,TMEM145,RDX,ROBO2,HSPA4L,KIF21A,ST6GAL1,CCDC88A,RCOR3,SOX11,ZBTB43,NFASC,POGZ,RGL1,STXBP1,ZC3H4,VPS13A,CAMTA1,SATB2,CUX2,RPGRIP1L,UBE3A,MICU3,ZBTB38,TMEM178A,FRMD6" MicroRNA hsa-miR-194:PITA hsa-miR-194:PITA_TOP PITA 1.30E-30 7.28E-27 3.82E-30 3.52E-29 61 271 "ACHE,OSBPL8,PITPNM2,APC,ZBTB10,STX16,CFL2,CNR1,BAG4,SLC35F1,RBM39,SOCS5,ELMSAN1,SNAP91,DMD,HS3ST2,SLC12A6,EDN1,MBNL2,PAN3,NRN1,ATP6V1H,STAU2,OGA,TNRC6A,GRB10,TJAP1,KCND2,STMN1,MAP2,MEIS2,MIA2,KITLG,MITF,IGSF11,PDE4D,PPP3CA,TMEM260,PTPRD,KHDRBS2,ZFHX4,SETD5,FBXW7,NCBP3,SALL1,CHD9,BTBD3,SEPHS1,SLC8A1,TMCC1,SOX3,SOX11,PEG10,CDK19,CLASP2,SS18,SEPT8,AP4E1,KAT6B,TRPS1,TRIM9" MicroRNA hsa-miR-485-3p:TargetScan hsa-miR-485-3p TargetScan 1.34E-30 7.51E-27 3.94E-30 3.63E-29 66 320 "KLHL32,CCDC85A,HACE1,ARHGAP20,APBB2,GAS7,CASK,CACNA1B,RUNX1T1,FOXN3,ABCG2,CLIP3,ERC2,PLCXD3,HDAC4,CHRDL1,NR1D2,PDCD6IP,DNM1L,FAM13A,CALCRL,ETV1,DLC1,FGF12,FLT1,CPLX2,PPARGC1A,KAT7,BVES,BACH2,IL6ST,LSAMP,MEIS1,MEIS2,HS6ST3,MXI1,PCSK5,PDE4D,FAM98B,PKIA,PTPRD,RAD51D,ERI2,FIGN,HUNK,KIF21A,CPEB3,PREX2,EPN2,MAPKBP1,PDZD2,RBM26,CLSTN2,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ANKS1B,EVI5,HNRNPA3,CPNE4" MicroRNA hsa-miR-539-3p:TargetScan hsa-miR-539-3p TargetScan 1.34E-30 7.51E-27 3.94E-30 3.63E-29 66 320 "KLHL32,CCDC85A,HACE1,ARHGAP20,APBB2,GAS7,CASK,CACNA1B,RUNX1T1,FOXN3,ABCG2,CLIP3,ERC2,PLCXD3,HDAC4,CHRDL1,NR1D2,PDCD6IP,DNM1L,FAM13A,CALCRL,ETV1,DLC1,FGF12,FLT1,CPLX2,PPARGC1A,KAT7,BVES,BACH2,IL6ST,LSAMP,MEIS1,MEIS2,HS6ST3,MXI1,PCSK5,PDE4D,FAM98B,PKIA,PTPRD,RAD51D,ERI2,FIGN,HUNK,KIF21A,CPEB3,PREX2,EPN2,MAPKBP1,PDZD2,RBM26,CLSTN2,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ANKS1B,EVI5,HNRNPA3,CPNE4" MicroRNA hsa-miR-1226:mirSVR_highEffct hsa-miR-1226:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-30 7.84E-27 4.11E-30 3.78E-29 91 603 "KCNH8,ACADM,AP2A2,CC2D2A,CEP126,OGT,SUGT1P4-STRA6LP-CCDC180,PKP4,MARCH3,TTLL9,ADAM15,CAMK2G,CAST,CLCN3,QKI,LETMD1,LRIG1,APPL1,KATNAL2,DCAF8,TM9SF4,ARMCX4,DDX46,SV2B,WDR20,DNM1,MAMLD1,ABCC5,KLHL5,PHF20L1,DCTN4,FCGR1A,KAT8,IP6K2,NOP56,UFM1,CELF1,CGREF1,NEU3,GLI2,GRIA2,FAM19A2,ADAMTS6,ACOT7,GABARAPL2,INPP5B,CREG2,SYTL4,MAP4,MAT2A,MBD1,DNHD1,NTRK3,ETFRF1,PCSK5,GNG2,PTPRE,RAD51D,NWD1,ROGDI,RASGRF2,RDX,GAL3ST4,CARF,ROBO1,ELP2,RPL15,FBXW7,GLDN,SCN8A,FBXO11,NUBPL,SLC8A1,NAPB,CPEB4,ABTB1,BDP1,LMO3,ITPRID2,ADHFE1,PRRC2C,OBSL1,AP4E1,TIAM1,AMACR,UGT8,ZIC1,TRIM9,ZNF154,ZSCAN26,KAT6A" MicroRNA "CTTTGCA,MIR-527:MSigDB" "CTTTGCA,MIR-527:MSigDB" MSigDB 1.48E-30 8.29E-27 4.35E-30 4.00E-29 55 217 "ADD2,KLHL13,DPP10,CDK13,HAP1,CAMK2A,PRC1,DCLK1,PUM1,FAM78B,MBNL2,KMT5B,EGR3,PAN3,NCALD,ACSL4,PTK2B,NBEA,NSG1,GGT7,TNRC6A,RNF165,SOX21,IDH3A,MBNL1,MEF2C,MYCN,NOVA1,OCRL,PAX6,GPR85,PFKFB4,PLEC,EPB41L4B,PPP2R5E,PBRM1,ZNF532,ROBO1,SALL1,SEMA6D,CHD9,FNDC3A,WDR47,CPEB4,SOX11,NFASC,VPS13A,PLCB1,TACC1,ANKRD12,SATB2,TCF12,ZFPM2,ZIC1,SENP7" MicroRNA hsa-miR-606:PITA hsa-miR-606:PITA_TOP PITA 1.61E-30 9.01E-27 4.72E-30 4.35E-29 64 301 "RALGAPA1,OSBPL1A,LRCH2,USP37,ZBTB10,SLC4A4,JAZF1,VXN,RUNX1T1,DLGAP2,QKI,COL9A1,AKAP5,CSNK1G3,CNTNAP2,ARHGAP24,MATR3,DMD,CPEB2,RGS17,EPB41,EYA1,ACSL4,AFF2,PPARGC1A,GPR34,FAM19A2,TOX2,ZHX1,MIER3,SMAP1,MBNL1,MN1,NEXMIF,MYT1,ZC3H12B,NFE2L2,NALCN,PIK3R1,LRP12,SCHIP1,LRRN3,PTPN13,TMEM255A,OXR1,HSPA4L,PPM1E,NLGN1,CCDC88A,TRIM67,CPEB4,RCOR3,SOX11,SP4,NKAIN2,CAMTA1,DNMBP,TCF4,TRPS1,UBE3A,DPYSL5,KLHDC1,SOCS4,SENP7" MicroRNA hsa-miR-1915*:mirSVR_highEffct hsa-miR-1915*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-30 9.11E-27 4.77E-30 4.39E-29 79 461 "EMILIN3,ADD2,KIAA1211,CCDC146,LCORL,RGS20,CALB2,USP6,CHN1,HECTD1,CPS1,RBM39,ANKRD44,GDA,DOCK4,ZFYVE16,DAPK1,IP6K1,USP3,DTNB,AASDH,WDPCP,EXTL2,RACK1,FGF11,SLC37A3,PDLIM5,DISC1,MSL3,LOXL3,GPD1,GRIA2,ADAMTS6,USP51,EID2B,IDH3B,IGF1,ZNF678,KCNN2,MAN2A2,ADAM22,MSR1,HS6ST3,MXI1,NNAT,CNOT4,LOC100128398,ZNF827,ZNF655,WDR25,ACSS3,ENOX1,RASGRF2,MSANTD2,RNASEL,SETD5,KLHDC8A,ATAT1,FHOD3,CNKSR2,ANKRD36,ZNF415,USP33,MCF2L2,NFASC,NKAIN2,ADHFE1,CAMTA1,ADGRL3,FAM200B,PMS2CL,C18orf54,CHST5,METTL3,ZNF28,UBE3B,TIGD6,MSRB3,IFT88" MicroRNA hsa-miR-185-5p:TargetScan hsa-miR-185-5p TargetScan 2.23E-30 1.25E-26 6.52E-30 6.00E-29 60 264 "ASIC1,PTCHD1,PCDH10,PRX,DNAH17,ATP1A3,SCARB1,DGKI,KCNAB3,ABCG1,RIMS4,ARHGAP32,DGKB,PITPNC1,C2CD2L,KLHL3,DNM1,DRP2,E2F6,PLEKHA1,MTSS1L,ERBB2,CORO2B,ANKFY1,INPP5K,GPR75,GPR12,KAT7,FAM222A,PADI2,KCNN3,LSAMP,MAT2A,PPM1L,MSI1,NFIX,PILRA,PKIA,PTPRG,DPF2,PRRT2,RIC8B,RORB,MYO18A,FAIM2,NMNAT2,ELOVL4,PHLDB1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CBX5,OSBP2,EVI5" MicroRNA hsa-miR-516b:PITA hsa-miR-516b:PITA_TOP PITA 2.23E-30 1.25E-26 6.54E-30 6.02E-29 52 193 "SYS1,AMPH,DPP10,ATP2A2,CACNA2D1,DCLK1,FOXN3,FAM19A5,MAP4K4,IST1,B3GAT3,DMD,CPEB2,PDCD6IP,GOLGA7,RGS17,EPHB1,AGAP3,FOXO3,GAD1,GPR162,TOX3,GRIA2,GRIN2D,BACH2,MEIS1,MPP2,GIT1,MYO5A,NEFM,PCDH9,OLA1,NLGN3,PCDH18,PMP22,NCBP3,FAM214B,HECW1,PEG10,POGZ,ELOVL4,ADGRL3,TRIM2,SZT2,SLC44A1,CELF4,POLR3H,ZFAND5,EVI5,KAT6A,MSRB3,ST8SIA2" MicroRNA hsa-miR-338-3p:TargetScan hsa-miR-338-3p TargetScan 2.32E-30 1.30E-26 6.78E-30 6.25E-29 67 333 "ADORA1,RNF150,ESYT2,MTUS1,KCTD16,KIAA1324,MARCH3,MARK4,N4BP2L1,CACNA2D1,CACNB4,CAMK2A,CAMK2G,COX4I1,SEC31B,AKAP12,HAPLN1,OSBPL3,FAM169A,PPP1R16B,ARHGAP32,DGKB,IP6K1,POM121,CDON,COPS4,AMOTL2,CINP,CHL1,CPLX2,RAB30,GPD2,PTPRT,FRMD3,NCKAP1L,HNF4G,IGF1,INSM1,METTL21A,KCND2,KIF2A,MAP2,MAPT,MBD1,MEF2C,DBNL,NOVA1,PPM1B,PPP1R1A,PTN,MORC4,FBXW7,KIAA0895L,HUNK,SALL1,CPEB3,MBD5,MYCBP2,ERC1,LARP4,MMS19,AP4E1,GDPD5,PPP1R3F,RGS7BP,JMJD1C,LAS1L" MicroRNA hsa-miR-525-3p:mirSVR_lowEffct hsa-miR-525-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.55E-30 1.43E-26 7.45E-30 6.86E-29 76 430 "DGCR6,EMILIN3,ESYT2,PCDH19,PDZD4,PITPNM2,AMPD2,SEMA7A,CDC14B,NAE1,CACNB4,VXN,SCARB1,IGLON5,CST3,PPP1R16B,ERC2,ARHGAP32,ZNF337,TBC1D5,LIN54,ARMCX4,PITPNC1,WDR20,SLC29A4,HIPK3,NRN1,SUCO,SEMA4D,PDLIM5,FAM49B,ZNF274,IP6K3,GRB10,ZBTB49,ADAMTS6,PADI2,KIF5A,PAXBP1,MN1,BLOC1S2,MXI1,HNRNPM,CDK18,FAM216A,PLCB2,PLIN1,SDK2,PPP1R1A,MAPK4,CNTLN,ZIK1,SLC25A48,PRRT2,CCDC82,KLHDC8A,ROBO1,TCP11L1,RYR3,ARX,SEPHS1,SLC11A1,INAVA,KDM4B,ZSWIM8,SSTR1,MPRIP,MLST8,SATB2,ZFPM2,TPM2,TRO,WIPF1,EML6,HNRNPA3,CPNE4" MicroRNA hsa-miR-34c-3p:PITA hsa-miR-34c-3p:PITA_TOP PITA 2.59E-30 1.45E-26 7.57E-30 6.97E-29 57 237 "MTUS1,MARCH4,CALB1,RUNX1T1,KCNAB3,CFL2,AKAP6,DOCK4,GAPVD1,RHOBTB1,CPEB2,MBNL2,TENM1,RCAN2,FHL1,SUCO,FAM49B,GABRG2,ARFIP1,PCDH17,MAP4K5,ZHX1,FRMD3,MIER3,DHX35,KIF2A,MAP2,MARK1,NEXMIF,ZC3H12B,GPR137C,PDE4D,PLCL1,TRHDE,STRN3,KANSL1,PTPRD,PTPRE,RBBP8,RPE,PEAR1,MRAS,CHD9,FNDC3A,SLC8A1,CCDC88A,SNCA,ARHGEF9,SYN2,SYT1,PCDHB3,PUM2,AKTIP,TRPS1,USP1,LAMP5,SLC38A1" MicroRNA "TGCTTTG,MIR-330:MSigDB" "TGCTTTG,MIR-330:MSigDB" MSigDB 2.96E-30 1.66E-26 8.65E-30 7.97E-29 65 314 "GPRASP2,AMPH,OGT,DPP10,APBB2,APC,ATP2B2,BACH1,CA12,CBFA2T2,DCLK1,FOXN3,NRXN3,QKI,PCYT1B,CSNK1G3,MAML1,FAM107B,DLX1,PHC2,MBNL2,GPHN,PPP1R1B,FGFR1,PDLIM5,NSG1,GNAO1,RNF165,SOX21,LRRC75A,MBNL1,LRP1B,MEF2C,ZC3H12B,PPM1B,KANSL1,PRKCB,DIRAS2,TRA2B,PPM1E,SYBU,PDZRN3,SOX11,SP4,ZNF423,STAU1,ARHGEF9,PLCB1,SYT5,TCF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TRPS1,MTCH1,PRTFDC1,PRDM8,ITM2C,JPH3" MicroRNA hsa-miR-125b-1*:mirSVR_lowEffct hsa-miR-125b-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.39E-30 1.90E-26 9.90E-30 9.11E-29 71 377 "XKR4,OLMALINC,ZNF608,FAM135A,SUGT1P4-STRA6LP-CCDC180,SLC4A4,KIF1A,BID,SCARB1,DGKI,DIS3L,SRSF11,FBXO7,QKI,CNR1,GREB1,RIMS2,MYEF2,RPS6KL1,DTNA,KMT5B,SLC43A2,KIAA1841,USP19,GNG4,GRIA2,HAS2,CELF5,MSL1,IPO5,PAXBP1,MEF2C,POC1B,SFR1,CNOT4,PCDH8,PFKFB3,KANSL1,GDPD1,CNTLN,PTPRG,KHDRBS2,RFX3,ZDHHC4,ZFHX4,CARF,YY1AP1,NEK11,SEMA6D,ATXN2,SCP2,SMPD3,CHD9,NLGN1,ZNF430,RBM34,SPTAN1,ZSCAN29,SEPT3,IQCE,TBL1X,TCF4,ZEB1,NAT16,PPIL6,DCBLD1,PLEKHH2,PARP11,UBE3B,NETO1,RNF146" MicroRNA "CACTGTG,MIR-128B:MSigDB" "CACTGTG,MIR-128B:MSigDB" MSigDB 3.60E-30 2.02E-26 1.05E-29 9.67E-29 65 315 "AK2,PITPNM2,APBA2,CDC14B,TMEFF1,SPTBN4,CHRD,DPY19L3,CA12,FOXN3,SOCS6,HECTD1,ARHGEF6,CNR1,ARMC8,CABP1,LETMD1,ZNF385A,CSF1,RGS6,SPATA2,ELMO1,ARRDC4,UBE2E3,MEGF11,GAD1,RUNDC3A,PTPRT,KAT7,MAP4K5,INSM1,MPP2,MXI1,ZC3H12B,NPTX1,NPTX2,NTRK3,ZNF827,PDE3A,PDPK1,PIK3R1,RASGEF1B,DIRAS2,RELN,FAM184A,KLHDC8A,RORB,SEMA6D,CASC3,PPM1E,CCDC88A,SP2,SP4,CLSTN2,SS18,NXT2,ELOVL4,SEPT3,SYT1,SIRT1,CBX5,ZNF24,EVI5,NAV3,KCNAB1" MicroRNA "CACTGTG,MIR-128A:MSigDB" "CACTGTG,MIR-128A:MSigDB" MSigDB 3.60E-30 2.02E-26 1.05E-29 9.67E-29 65 315 "AK2,PITPNM2,APBA2,CDC14B,TMEFF1,SPTBN4,CHRD,DPY19L3,CA12,FOXN3,SOCS6,HECTD1,ARHGEF6,CNR1,ARMC8,CABP1,LETMD1,ZNF385A,CSF1,RGS6,SPATA2,ELMO1,ARRDC4,UBE2E3,MEGF11,GAD1,RUNDC3A,PTPRT,KAT7,MAP4K5,INSM1,MPP2,MXI1,ZC3H12B,NPTX1,NPTX2,NTRK3,ZNF827,PDE3A,PDPK1,PIK3R1,RASGEF1B,DIRAS2,RELN,FAM184A,KLHDC8A,RORB,SEMA6D,CASC3,PPM1E,CCDC88A,SP2,SP4,CLSTN2,SS18,NXT2,ELOVL4,SEPT3,SYT1,SIRT1,CBX5,ZNF24,EVI5,NAV3,KCNAB1" MicroRNA hsa-miR-4304:mirSVR_lowEffct hsa-miR-4304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-30 2.08E-26 1.08E-29 9.96E-29 80 478 "ASPHD1,KLHL32,CCDC85A,KIAA1211,ADRB2,CASKIN1,TBC1D14,CADPS,CDK13,NCOA1,ATP1B3,CACNB4,LDB2,CHN1,NDST3,NRXN3,FAM19A5,MAP4K4,RTTN,CREM,NCOR1,SNCAIP,CSF1,ARHGEF10,CSNK1G3,GREB1,ARHGAP24,ALKBH8,DTNA,EIF4G2,OLFM1,FHL1,PPARGC1A,ELOVL5,GABARAPL2,C2orf72,LRRC25,ZIC5,SCIN,ITPKA,STXBP5,LIFR,LIMS1,MEIS2,MXI1,IDNK,NEK1,IGSF11,P2RX7,PKD1,GPSM2,PURG,SCHIP1,SEPT4,MBOAT7,KANSL1,QRICH1,PTCH1,USP47,CLIP1,AP1AR,SCN7A,SCN8A,BTBD7,SNRPN,UHRF1BP1L,KDM4C,ERC1,NKAIN2,NXT2,DIP2A,KLHL7,ERCC6L2,TPM1,UGT8,XPO1,XRCC4,MKRN3,CELF4,PHTF2" MicroRNA hsa-miR-874-3p:TargetScan hsa-miR-874-3p TargetScan 4.17E-30 2.33E-26 1.21E-29 1.12E-28 57 239 "PTCHD1,BEND6,DYNLL1,BCL7A,MTMR3,MYRF,RUNX1T1,PCYT1B,HAPLN1,CNTNAP2,GREB1,PPP6R2,IST1,RHOBTB1,EGR3,PPP1R1B,MED12L,FGF1,DCTN2,ATP2C1,CPLX2,CRCP,FICD,RNFT2,IGFBPL1,MBD1,MXI1,MYO9A,NRCAM,PAX6,GNG2,PPP5C,PSD,BCAS3,PIGG,RGS4,CYB561D1,CNKSR2,CPEB4,EPC1,LHPP,CLSTN2,EXOC7,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,NR2C2,BCL2L13,RBFOX3,GDPD5,HNRNPA3,MSRB3" MicroRNA hsa-miR-3201:mirSVR_highEffct hsa-miR-3201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.33E-30 2.42E-26 1.26E-29 1.16E-28 89 587 "FMNL2,ZNF608,KCTD16,NME5,OSBPL6,TAOK1,TMEFF1,CADPS,N4BP2L1,ADAM23,SYNJ1,CALB1,KCNAB3,ZMYM4,SRP14-AS1,SLC4A8,ZSCAN23,DOCK4,KATNAL2,DCAF8,IST1,RAB39B,GOLT1B,EDIL3,EDN1,PHF20L1,TENM1,STARD3NL,DCTN4,LRRC17,CDKL3,F5,ABCA8,ACSL4,GORAB,SCARA3,PCYOX1,COQ5,SMC2,UFM1,CELF1,HRASLS5,IQGAP2,KIAA1841,ADAM28,MALT1,GPR37,DIDO1,GSN,IRF8,ZIC5,STXBP5,NCOA7,MAT2A,MEIS1,MITF,BLOC1S2,NRBP2,NCAM2,NF1,OCRL,LOC100128398,PCDH9,SNX10,KANSL1,GRAMD1C,CNTLN,MARCH1,SUSD4,RAP1GDS1,RBBP6,RGS12,ROBO2,CCDC102B,SEPHS1,INAVA,LIMCH1,RBM26,ST5,STAU1,SEPT8,DIP2A,ATMIN,AMACR,STXBP4,GUSBP1,EPM2A,GAN,JPH3" MicroRNA hsa-miR-3186-5p:mirSVR_lowEffct hsa-miR-3186-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.03E-30 2.81E-26 1.46E-29 1.35E-28 73 401 "SYS1,HACE1,WDR35,HFM1,ANK2,PHYHD1,MADD,ARHGDIA,PLA2G4C,CCAR2,ADGRB2,MIR9-3HG,CFLAR,SYNJ2,CBLN1,NRXN3,IGLON5,IQCK,FAM169A,CTH,DCAF4,RUBCN,DAPK1,MAMLD1,ABCC5,EDN3,PHC2,LRRC17,NCALD,CHST15,FCGRT,SUCO,PCYOX1,ERGIC3,FAM120B,GLYR1,CLASRP,ATOH8,FRMD5,NEGR1,CELF5,SCIN,KCNN3,MID1,SLC11A2,PFKFB3,SNX10,JAKMIP1,PCDHB17P,PIGG,KHDRBS2,RIC8B,TNFRSF19,FOXRED1,SH3GL3,NAPB,RCOR3,ANKRD36,INAVA,CMTR2,SNRPN,SOX3,IQSEC2,MESP1,STXBP1,KIAA1107,TBCEL,CYB561A3,CDH22,TRO,LINC02210,SEMA3B,LAS1L" MicroRNA hsa-miR-326:TargetScan hsa-miR-326 TargetScan 5.40E-30 3.02E-26 1.57E-29 1.45E-28 70 369 "RALGAPA1,C3orf14,EMILIN3,ELFN2,CASKIN1,DYNLL1,ATP2B2,ATP6V1G2,DGKI,DLGAP2,QKI,IGLON5,NSL1,CRY2,DGKG,AIF1L,CHRDL1,PDCD6IP,DTNB,HEYL,CELSR3,EGR3,EIF1,ERBB4,APC2,CORO2B,FCGR3A,FGF1,FGF11,FGFR1,ANKFY1,NEURL4,CHL1,CPLX2,KIAA1958,GPD2,PADI2,SCIN,LRRTM1,KCNB1,KCNJ5,MEST,SAMD14,MYO9A,NFIX,NOVA2,PALM,PDE1B,PLEC,PLXNB1,SDK2,POLR2F,PKIA,MAPK4,BCAS3,NKAIN1,IQSEC3,DPF2,KLHDC8A,FNDC3A,BTBD3,MBD5,FAIM2,FAM126B,ERC1,RHBDL3,CDH22,KCNK12,ELFN1,PPP1R3F" MicroRNA hsa-miR-330-5p:TargetScan hsa-miR-330-5p TargetScan 5.40E-30 3.02E-26 1.57E-29 1.45E-28 70 369 "RALGAPA1,C3orf14,EMILIN3,ELFN2,CASKIN1,DYNLL1,ATP2B2,ATP6V1G2,DGKI,DLGAP2,QKI,IGLON5,NSL1,CRY2,DGKG,AIF1L,CHRDL1,PDCD6IP,DTNB,HEYL,CELSR3,EGR3,EIF1,ERBB4,APC2,CORO2B,FCGR3A,FGF1,FGF11,FGFR1,ANKFY1,NEURL4,CHL1,CPLX2,KIAA1958,GPD2,PADI2,SCIN,LRRTM1,KCNB1,KCNJ5,MEST,SAMD14,MYO9A,NFIX,NOVA2,PALM,PDE1B,PLEC,PLXNB1,SDK2,POLR2F,PKIA,MAPK4,BCAS3,NKAIN1,IQSEC3,DPF2,KLHDC8A,FNDC3A,BTBD3,MBD5,FAIM2,FAM126B,ERC1,RHBDL3,CDH22,KCNK12,ELFN1,PPP1R3F" MicroRNA hsa-miR-510:PITA hsa-miR-510:PITA_TOP PITA 5.45E-30 3.05E-26 1.58E-29 1.46E-28 45 141 "LRFN2,GPRASP2,SLC4A4,C5,CAMK2G,LDB2,MAGI1,FOXN3,CLIP3,MATR3,ZC3H11A,DMD,DNAJB6,EDNRA,PHC2,RCAN2,EPHB1,MRVI1,IP6K2,GATM,TTBK1,COQ10A,HLF,MAT2A,MBNL1,MYO6,NOVA1,TMOD2,ANKRD16,SDK2,PPP2R5E,RET,RORB,HUNK,FNIP1,ST8SIA1,PPP4R3A,SLC8A1,TRIM67,PUM2,CCDC136,POLR3H,DNALI1,KAT6A,ST8SIA2" MicroRNA hsa-miR-370:mirSVR_highEffct hsa-miR-370:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.59E-30 3.13E-26 1.62E-29 1.50E-28 89 589 "CASKIN1,KCTD16,RTL9,USP35,PCDH10,SEMA4G,PPP4R4,SLC4A4,N4BP2L1,ADGRB2,DNAJC27-AS1,BID,ARHGEF7,CDC25B,MAGI1,BAG4,CSF2RA,PDE4DIP,UBXN2A,PHF14,DOCK4,HDAC4,PABPC5,EXOG,USP3,PHF20L1,SUGP2,MRO,EPHB1,GPHN,MRPL37,FCGR1A,FDFT1,FER,FGF11,WDR83,UFM1,OGA,GLYR1,ADAMTS13,RASSF8,SMAP1,ZNF678,JAK2,PIK3AP1,MBNL1,XRRA1,RTL5,NF1,NME4,DPY19L2P2,ZNF655,FAM216A,FXYD1,EXOSC10,ING3,SEPT4,PPM1B,PRKACB,PTPRB,ZSCAN2,RAP1GDS1,CARF,EPHA10,ATP8B4,ATAT1,ATXN2,SCP2,SH3GL3,PPM1E,AMBRA1,CDK5RAP2,SMARCD3,MBD5,SS18,SULF2,STXBP1,SZT2,AP4E1,AKTIP,BHLHB9,TPM2,DCBLD1,CCDC136,TOM1L2,MAP3K12,PRTFDC1,PRDM10,RNF170" MicroRNA hsa-miR-4259:mirSVR_highEffct hsa-miR-4259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.81E-30 3.81E-26 1.98E-29 1.82E-28 90 603 "NCKAP5,XKR4,NDRG3,RTL9,KIAA1324,SPOP,MARCH4,APC,APOC2,TNRC6C,SEMA4G,MARK4,NCOA1,ATP2A2,BACH1,NRP2,CBLN1,USP2,TIGD7,CHN2,RAB28,PPT2,COL4A5,ZFP28,SEC31B,SLITRK5,BOC,MYADM,KATNAL2,HEPH,MYEF2,DLX1,RAB39B,MBNL2,C8orf37,EPB41,ZNF549,CLVS1,CHST15,FDFT1,SPSB4,PRKAG2,UFM1,MEGF10,DISC1,SRCAP,BRD8,ZNF276,TNRC6A,CCDC184,KAT7,FAM222A,HMGCR,TCEAL6,INSM1,KTN1,PPM1L,TCEAL5,P2RX7,JAKMIP1,PMP22,TMEM260,PTPRH,TMEM255A,GAL3ST4,GTDC1,FBXW7,RPS6KA2,KCNIP1,ATXN2,KDM3A,SP2,SAMSN1,STAU1,SEPT8,ADHFE1,KLHL7,SYN2,ZEB1,TIAM1,R3HDM1,FLRT2,CCDC14,CELF4,RNF103,SLC17A7,ST7,UBE3B,FXR1,NETO1" MicroRNA hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA_TOP PITA 7.25E-30 4.06E-26 2.10E-29 1.94E-28 61 279 "XKR4,PWWP2A,PITPNM2,OGT,N4BP2L1,LDLRAD4,FOXN3,TAOK2,QKI,COL4A5,CPS1,SOCS5,RIMS4,USP6NL,DBT,ELMSAN1,SPOCK3,ELN,MEX3B,AGAP3,FOXO3,CAMKK2,GPR37,BACH2,SMAP1,IGF1,ZIC5,MEST,MITF,MYCN,NEXMIF,CLDN11,ENPP2,PIK3C2A,PIK3R1,PURG,PMP22,EPB41L4B,PRKAB2,SNRK,OXR1,REV3L,GTDC1,KIRREL1,PPM1E,NAPB,TET1,DOP1A,HECW1,PEG10,SPTAN1,CLASP2,STX1A,CAMTA1,AP4E1,ZNF346,TRPS1,TUBB2A,WIPF1,NAV3,ADAMTS10" MicroRNA hsa-miR-140-3p:PITA hsa-miR-140-3p:PITA_TOP PITA 7.52E-30 4.21E-26 2.18E-29 2.01E-28 66 329 "NDRG3,USP31,LDLRAD4,USP6,ZMYM4,QKI,AKAP5,SLC35F1,SOCS5,HDAC4,DNM1,NR1D2,CPEB2,DRP2,GOLT1B,KMT5B,EGR3,TENM1,PLEKHA1,AFF2,AHDC1,PCDH17,SPIN1,GRM2,MIER3,HLF,KCNB1,KIF5A,MAP2,MEIS2,NFYA,NOVA1,TBC1D25,PCDH8,OLA1,PURG,SCHIP1,KANSL1,RASGEF1B,PKIA,VPS13C,WBP1L,PTCH1,KHDRBS2,ROBO2,FBXW7,PPM1E,SNAP25,SOX11,SP4,CDK19,ZC3H4,PLCB1,SYN1,TCF4,SATB2,DOCK9,SIRT1,ZFPM2,TRPS1,USP1,ZBTB38,URM1,PDSS2,FRMD6,SOCS4" MicroRNA hsa-miR-611:mirSVR_lowEffct hsa-miR-611:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.65E-30 4.28E-26 2.22E-29 2.04E-28 76 437 "RALGAPA1,XKR4,AP2A2,TBC1D14,MAP4K3,TNRC6C,MADD,ADAM15,LINC00847,CACNA1B,CACNA2D1,THSD7A,KALRN,TIGD7,CHN2,CLCN3,PICK1,FAM149A,AKAP6,CSF2RA,CNTNAP2,PNPLA8,DCAF4,ZNF337,TMCC2,EDN1,EDNRA,EIF1,NOP56,TMEM175,MEGF10,SULT1C4,HTATSF1,LILRA2,GRIA2,FRMD3,ATXN2L,SOWAHA,SLC35G1,TTYH2,AQP11,TM6SF1,PTOV1,NFIX,NTRK3,NLE1,MAPKAP1,PIGG,PTPRB,PTPRG,C1orf109,SLC25A36,ZNF532,CARF,SATB1,SH3GL3,SEC31A,ZNF430,CPEB4,POGZ,ZC4H2,STAC2,KANK1,ADAMTS17,SYN1,PDLIM2,SIN3B,ERCC6L2,RUSC1,UCHL1,PLPPR2,ANKS1B,CIAPIN1,SEMA3B,UBE3B,DPF3" MicroRNA "TGCACTG,MIR-152:MSigDB" "TGCACTG,MIR-152:MSigDB" MSigDB 7.68E-30 4.30E-26 2.22E-29 2.05E-28 62 289 "PLEKHH1,HECW2,PCDH10,ANK2,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,SYNJ1,CABP7,CAMK2A,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,MED12L,PRKAG2,NEURL4,ARFIP1,PPARGC1A,TNRC6A,KDM2B,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,KANSL1,ROBO1,ROBO2,RORB,RXRA,CHD9,FBXO11,BTBD3,EPN2,CPEB4,USP33,SOX11,CDK19,SYT1,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,KLC2,RICTOR,USP32P2,JPH3" MicroRNA "TGCACTG,MIR-148B:MSigDB" "TGCACTG,MIR-148B:MSigDB" MSigDB 7.68E-30 4.30E-26 2.22E-29 2.05E-28 62 289 "PLEKHH1,HECW2,PCDH10,ANK2,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,SYNJ1,CABP7,CAMK2A,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,MED12L,PRKAG2,NEURL4,ARFIP1,PPARGC1A,TNRC6A,KDM2B,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,KANSL1,ROBO1,ROBO2,RORB,RXRA,CHD9,FBXO11,BTBD3,EPN2,CPEB4,USP33,SOX11,CDK19,SYT1,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,KLC2,RICTOR,USP32P2,JPH3" MicroRNA "TGCACTG,MIR-148A:MSigDB" "TGCACTG,MIR-148A:MSigDB" MSigDB 7.68E-30 4.30E-26 2.22E-29 2.05E-28 62 289 "PLEKHH1,HECW2,PCDH10,ANK2,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,SYNJ1,CABP7,CAMK2A,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,MED12L,PRKAG2,NEURL4,ARFIP1,PPARGC1A,TNRC6A,KDM2B,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,KANSL1,ROBO1,ROBO2,RORB,RXRA,CHD9,FBXO11,BTBD3,EPN2,CPEB4,USP33,SOX11,CDK19,SYT1,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,KLC2,RICTOR,USP32P2,JPH3" MicroRNA hsa-miR-3165:mirSVR_highEffct hsa-miR-3165:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.72E-30 4.32E-26 2.23E-29 2.06E-28 80 483 "RALGAPA1,OSBPL1A,PHF12,CDK10,ZBTB10,NCOA1,ADAM23,SYNJ2,GYG2,ZMYM4,HECTD1,C2CD2,LRRC3B,VCAN,PDE4DIP,GREB1,ARMCX2,RHOBTB1,EGFR,EPHB1,ERCC2,ADGRV1,ACSL4,FGF12,POLK,NOP56,NBEA,CGREF1,AP4B1,FAM120B,PPARGC1A,TTBK1,GPR12,TOX2,LRRC75A,IL6ST,INPP5B,PPM1L,NCAM2,NEK1,NF1,NPY,DNHD1,PIK3C2A,SNX10,FAM216A,PPP2R5E,ANKHD1,GTDC1,RGS12,KIRREL1,MRAP2,ZC3H14,TCP11L1,FNIP1,TRA2B,PKNOX2,ATF7IP,TET1,MAST1,LIMCH1,FNBP1,ERC1,CLSTN2,NEK4,CEP68,SYPL1,SMG6,C18orf54,STXBP4,ZKSCAN5,VLDLR,EMSY,CIAPIN1,SIGLEC10,PARP11,PDSS2,DOCK8,TRAM2-AS1,FRMD6" MicroRNA hsa-miR-590-5p:PITA hsa-miR-590-5p:PITA_TOP PITA 9.20E-30 5.15E-26 2.66E-29 2.45E-28 59 261 "RALGAPA1,PTCHD1,CASKIN1,BCL7A,FUBP1,KRIT1,CFL2,SOCS6,CNOT8,CNTFR,ARHGAP24,SLC12A6,SNX29,RASGRP1,PLEKHA1,PAN3,SCML2,ST3GAL6,ANKFY1,CHL1,GABRG2,MSTN,FRMD3,RBPJ,IL12A,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MYO6,NELL2,PIK3R1,PPP3CA,MAPK10,TMEM260,RDX,PBRM1,AP1AR,SATB1,CPEB3,FBXO11,BTBD3,TET1,PDZD2,ITPRID2,MPRIP,PHLDB1,PLCB1,CAMTA1,TIAM1,SGK3,VSNL1,TRIM9,TMEM237,RNF103,WNK3,NETO2" MicroRNA hsa-miR-125b:PITA hsa-miR-125b:PITA_TOP PITA 9.46E-30 5.30E-26 2.73E-29 2.52E-28 65 320 "ABHD6,LRFN2,MTUS1,USP37,SLC4A4,ADGRB1,MTMR3,ARHGEF1,SCARB1,SULT4A1,ZNF385A,HINFP,NCOR2,FAM131B,TM9SF4,IST1,IP6K1,ELMSAN1,RUSC2,ZC3H11A,DTNB,ABCC5,PHC2,CNNM1,EGR3,ERBB4,ZNF589,SEMA4D,GGT7,LOXL3,GRB10,SPACA9,MAN1B1,HMGCR,SLC6A17,LIFR,ADAM11,MEIS2,MSI1,MYT1,ZC3H12B,NEFM,CHAMP1,RETREG2,DRAM2,SH3TC2,KCNIP3,SCN2B,CPEB3,PPP4R3A,ABTB1,SOX11,SPTB,ZSCAN29,SATB2,DICER1,NPL,TRPS1,SLC35A4,KLC2,CRB2,TMEM198,SLC17A7,MSRB3,SOCS4" MicroRNA hsa-miR-125a-5p:PITA hsa-miR-125a-5p:PITA_TOP PITA 9.46E-30 5.30E-26 2.73E-29 2.52E-28 65 320 "ABHD6,LRFN2,MTUS1,USP37,SLC4A4,ADGRB1,MTMR3,ARHGEF1,SCARB1,SULT4A1,ZNF385A,HINFP,NCOR2,FAM131B,TM9SF4,IST1,IP6K1,ELMSAN1,RUSC2,ZC3H11A,DTNB,ABCC5,PHC2,CNNM1,EGR3,ERBB4,ZNF589,SEMA4D,GGT7,LOXL3,GRB10,SPACA9,MAN1B1,HMGCR,SLC6A17,LIFR,ADAM11,MEIS2,MSI1,MYT1,ZC3H12B,NEFM,CHAMP1,RETREG2,DRAM2,SH3TC2,KCNIP3,SCN2B,CPEB3,PPP4R3A,ABTB1,SOX11,SPTB,ZSCAN29,SATB2,DICER1,NPL,TRPS1,SLC35A4,KLC2,CRB2,TMEM198,SLC17A7,MSRB3,SOCS4" MicroRNA "GGGACCA,MIR-133A:MSigDB" "GGGACCA,MIR-133A:MSigDB" MSigDB 9.78E-30 5.47E-26 2.82E-29 2.60E-28 51 190 "OSBPL8,ARHGDIA,PCDHGB4,BACH1,ADGRB1,PTBP2,USP6,ARHGEF2,CLTC,ZNF385A,SOCS5,KIAA0040,GAPVD1,IP6K1,ELMSAN1,DNAJB6,TNK2,ACSL4,RAPGEF6,TTBK1,ATOH8,AGBL5,IL6ST,KCNH2,NNAT,NPTX1,PCDHGC3,PFKFB3,ZDHHC8,SEMA5B,RETREG1,PRRT2,SCN2B,SOX11,MYCBP2,NFASC,STX1A,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,USP32P2,CELF4" MicroRNA "GGGACCA,MIR-133B:MSigDB" "GGGACCA,MIR-133B:MSigDB" MSigDB 9.78E-30 5.47E-26 2.82E-29 2.60E-28 51 190 "OSBPL8,ARHGDIA,PCDHGB4,BACH1,ADGRB1,PTBP2,USP6,ARHGEF2,CLTC,ZNF385A,SOCS5,KIAA0040,GAPVD1,IP6K1,ELMSAN1,DNAJB6,TNK2,ACSL4,RAPGEF6,TTBK1,ATOH8,AGBL5,IL6ST,KCNH2,NNAT,NPTX1,PCDHGC3,PFKFB3,ZDHHC8,SEMA5B,RETREG1,PRRT2,SCN2B,SOX11,MYCBP2,NFASC,STX1A,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,USP32P2,CELF4" MicroRNA hsa-miR-371-3p:mirSVR_lowEffct hsa-miR-371-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.84E-30 5.51E-26 2.84E-29 2.61E-28 77 450 "NCKAP5,KLHL32,PSMG3-AS1,KIAA1211,OGT,USP37,CDK10,CDK13,DPY19L3,ADGRB2,NRP2,AP1M1,PTBP2,SLC25A14,SEPT7,MAGI1,ZNF385A,CS,RGS6,CCDC144A,HDAC9,ZNF804A,KIAA0753,SNAP91,DNM1L,PLXNC1,EMX2,GPHN,PIPOX,EYA1,MRVI1,FCGR1A,FLT1,NBEA,CINP,MEGF11,GCNT2,ARFIP1,SERP2,HNF4G,C9orf129,SMAP1,IDH3B,INPP5B,MYO7A,SFR1,DPY19L2P2,PCDH9,XRN1,PIGG,UBR7,ATP8B4,HSD11B1L,CSRNP3,ATXN2,PEAR1,ARX,DHX30,CPEB4,SMARCD3,MBD5,KIF13A,CMTR2,USP33,SOX3,UHRF1BP1L,CLASP2,SLC37A2,SYNE1,DCBLD1,SGK3,UGT8,CCDC14,ZNF711,LYPD6,ZNF213,SENP7" MicroRNA hsa-miR-513c:PITA hsa-miR-513c:PITA_TOP PITA 1.10E-29 6.13E-26 3.15E-29 2.90E-28 56 234 "HECW2,ALCAM,OGT,PPP4R4,CALM1,FOXN3,QKI,MAP4K4,PREPL,RBM39,CSNK1G3,CNTNAP2,SPOCK2,GIT2,DYNC1I1,SLC12A6,PAN3,EXTL2,CLVS1,HPCAL4,SYNCRIP,NBEA,MEGF11,GABRB3,CPLX2,PCDH17,TMEM121B,CIT,SYNPO,IDH3A,MBNL1,NEXMIF,NEFM,NEFH,NOVA1,NALCN,XRN1,MINDY2,PTPRD,PTX3,PPP4R3A,SLC6A8,KDM4C,ARHGAP26,SYN1,SYPL1,FBXW11,TIAM1,TRPS1,UBE3A,FLRT2,ZNF711,SLC30A4,PHTF2,FXR1,SOCS4" MicroRNA hsa-miR-518c:mirSVR_lowEffct hsa-miR-518c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-29 6.53E-26 3.36E-29 3.09E-28 95 671 "NDRG3,FMNL2,PSMG3-AS1,ADD1,BRAP,RNF150,OLMALINC,ASGR1,FUBP1,JAZF1,THSD7A,KALRN,PRC1,CCPG1,SRSF11,SOCS6,QKI,SULT4A1,MAP4K4,ARHGEF6,MYRIP,ZNF521,AKAP12,ANKRD44,GAPVD1,KCTD8,DAPK1,DGCR5,RHOBTB1,DMPK,SLC29A4,CDON,ABCC5,SEMA3D,EIF1,MTSS1L,MRPL37,ETV1,DNAJC27,MED12L,IP6K2,NELFCD,SDCBP2,MEGF11,TUBA8,PCLO,AGBL5,SYTL4,MAP6,MPP2,LYRM9,MYO6,NME4,OPA1,PFKFB2,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,FBXW7,SCN2B,HSPA4L,ARX,SLC6A8,CPEB4,PDZRN3,KDM3A,SEPT8,STAC2,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,ZMAT3,ZNF106,RIMBP2,TRIO,TSC1,UCHL1,VLDLR,ZNF74,CELF4,ZFAND5,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-1260b:mirSVR_highEffct hsa-miR-1260b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-29 7.49E-26 3.85E-29 3.55E-28 91 621 "NCKAP5,BRAP,AK2,CDC42BPA,PARG,SLC2A11,CFLAR,SYNJ2,PTBP2,CD86,CDH2,SOCS6,HECTD1,LETMD1,MYRIP,RNF14,GDA,SIPA1L1,ZFYVE16,ZNF337,TBC1D5,DBI,DBN1,HS3ST2,TMEM35A,EPB41,RABEPK,STX2,ZNF391,HSPA12B,FCGRT,FER,GTF2IRD2,FGFR1,SUCO,FOXF2,IQCG,SLC37A3,TMEM107,UFM1,NSG1,IQGAP2,DISC1,NEU3,SRCAP,SULT1C4,MSL3,ZNF638,TDRKH,LPAR4,PLCD4,RASSF8,CFAP126,LRRC75A,IL6ST,INPP5B,KCNN3,KIF5A,ASPRV1,PPM1L,CLDN11,OXTR,PLCL1,GRAMD1C,BDNF-AS,PTPRD,RASGRF2,RET,RGS12,TMLHE,ROBO2,ELP2,KCNIP1,RXRA,NCBP3,SCN8A,FNIP1,FOXRED1,KIF21A,AMBRA1,CPEB4,DBNDD2,RBM26,ADHFE1,NSFL1C,SYNE2,TPCN2,SYNE1,SYNPO2,LYPD6,RNF146" MicroRNA hsa-miR-220b:mirSVR_highEffct hsa-miR-220b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-29 7.49E-26 3.85E-29 3.55E-28 91 621 "RTL9,PLA2G4C,DNAH17,KALRN,LRBA,RCBTB2,RAB28,COL4A5,ABI3BP,CSF2RA,SEC24C,CSNK1G3,SUSD5,PDE4DIP,SLITRK5,GPRASP1,DDX46,SACS,MAMLD1,DNM1L,GOLT1B,EGR3,PAN3,GPHN,RASL12,TMEM132C,ST3GAL6,SLC37A3,UFM1,ATP2C1,CELF1,CHL1,TUBGCP4,KDM2B,GPD2,GRIA2,PLCD4,AP4S1,SMAP1,MYLK2,SCIN,KCND2,STXBP5,MARK1,PPM1L,CNOT4,PCSK5,PDE4B,GNG2,ZNF655,PURG,SCHIP1,SEPT4,PPM1B,NKAIN4,PKIA,ZCWPW1,FIGN,EXD2,CARF,SNX22,RPL15,SPIN3,RMI1,ATXN7,CASC3,SUPT20H,PPM1E,WDR47,SLC12A2,SLC12A4,MYO16,SPP1,TSPYL2,POGZ,ZNF302,SULF2,ZC3H4,VPS13A,DNAJC9,SYN2,TPCN2,DOCK9,ARHGAP9,TPM2,UBE3A,P2RY12,TRIM9,MDH1B,DOCK8,FAM198A" MicroRNA hsa-let-7d*:mirSVR_lowEffct hsa-let-7d*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-29 7.53E-26 3.87E-29 3.56E-28 72 396 "ZNF608,CCDC146,TMEFF1,DPY19L3,DOCK11,NAE1,SRSF11,RAB33A,HECTD1,LETMD1,AKAP5,PLXNA4,APPL1,PLCXD3,GAPVD1,ZFYVE16,MATR3,YTHDC1,HS3ST2,ARRDC4,DTNA,E2F5,EGFR,PLEKHA1,EYA1,ARMCX1,SH3YL1,FLT1,TRMO,GRIA2,ELOVL5,ACOT7,TCEAL6,LIFR,MAP6,MYO9A,NF1,NOVA1,NRCAM,PCDH8,CCSER2,XRN1,PCDH18,GDPD1,MASP1,FAT4,RAP1GDS1,OXR1,MSANTD2,REV3L,ZNF532,ZC3H14,SATB1,SH3GL3,KIF16B,SHC4,FNDC3A,ELMO2,SLC22A4,RCOR3,INAVA,FAM219A,PDZD2,SSTR2,ZSCAN29,RGL1,SULF2,ATMIN,ZFPM2,TLR4,ZIC1,FAM47E" MicroRNA hsa-miR-4267:mirSVR_highEffct hsa-miR-4267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-29 7.62E-26 3.91E-29 3.60E-28 89 596 "ABCF1,KCNH8,ACADM,AXIN2,UNC5A,AGT,SEMA6A,GPRASP2,SUGT1P4-STRA6LP-CCDC180,ASGR1,NUMB,ADAM15,ADGRB2,BARD1,CFLAR,CALB2,KALRN,RAB33A,CNR1,SLC4A8,SMARCAL1,SEC24C,ARHGEF10,PITPNM3,ZSCAN23,IST1,SGSM2,TOM1,STRADA,DCTN2,UFM1,STAU2,RAPGEF6,KIAA1841,BRD8,ZNF276,MSL3,ZNF782,SOX21,RNFT2,ACOT7,HNF4G,CPT1C,KIF5A,MEST,SCAMP5,MSR1,MXI1,NFE2L2,TREM2,OLA1,MINDY2,MAPK3,TMEM260,PTPRO,FAM66C,DCUN1D2,CARF,PCMTD2,ABCA11P,HSD11B1L,TRA2B,FAM81A,PEX26,DHX30,SIRT2,ELMO2,ZNF423,SPTB,ITPRID2,CEP68,PLCB1,DNMBP,SATB2,SZT2,DOCK9,AP4E1,RIMBP2,TPM1,TSN,HSPBP1,RPL7L1,PCDH20,FSTL5,URM1,PPP1R3F,NELFE,UBE3B,CASC15" MicroRNA hsa-miR-744*:mirSVR_highEffct hsa-miR-744*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-29 7.62E-26 3.91E-29 3.60E-28 89 596 "KLHL32,ALCAM,PCDH10,AMPH,ARNTL,CDK13,SYNJ1,KALRN,PTBP2,CAST,CERS5,CD86,LRRFIP1,LOC730101,NDST3,AKAP7,ARMC8,RBM39,CSNK1G3,BOC,HDAC9,GPRASP1,MATR3,DAPK1,DMD,DOCK2,DNM1L,EDN3,GPHN,IGSF6,ZNF391,OLFM1,BAIAP2,RASL10A,MEGF10,GAD1,C15orf41,DISC1,PPARGC1A,TXNL4A,CRCP,RNPS1,SPIN1,KCNMB4,WDFY3-AS2,CCDC184,STON1,VSIG4,LRRC75A,IL6ST,LIMS1,MEF2C,GPR173,SNX10,ING3,SAMD9,EML5,CEP97,SLC25A48,ZMAT4,ZFHX4,SUGCT,RORB,SAFB,SEMA6D,SCP2,HSPA4L,PPM1E,FNDC3A,NAPB,RCOR3,SNRPN,TRERF1,SP4,NKAIN2,SS18,THRA,ERCC6L2,TRO,RPL7L1,NPDC1,FTSJ1,FIP1L1,FAM47E,PARP11,DOCK8,CASC15,ADAMTSL3,SNX14" MicroRNA hsa-miR-490-3p:mirSVR_highEffct hsa-miR-490-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.42E-29 7.95E-26 4.08E-29 3.75E-28 81 499 "DPY19L2P4,OGT,MAP4K3,UPRT,STK33,ZNF583,C5,IL33,CALB2,KALRN,CLDN10,KYAT1,CERS5,LRBA,ARHGAP33,MAGI1,TPP1,LY86,CNR1,AHCTF1,ANKRD44,CCDC144A,ZFYVE16,HEPH,FBXL5,FSD1L,KMT5B,RGS17,VPS13B,MFSD10,CEP85L,ZNF589,POLR1B,GABRG2,IGSF5,MSTN,ADAM28,PCDH17,STMN2,GRIA2,UBE2QL1,RBPJ,IL6R,TTYH2,NCOA7,CLEC18A,ZNF680,MSI1,MYO7A,NEK1,CNOT4,CHAMP1,PDE4D,NALCN,MBOAT7,GRAMD1C,HYDIN,ZSCAN32,OXR1,GTDC1,KIF7,BAALC,ADAL,ZFP2,SH3GL3,PEX26,PKNOX2,ANKRD36,FAM126B,SP4,ZSCAN29,DIP2A,NUDT10,DNAJC9,SYT1,SLC44A1,TP53BP1,ZKSCAN5,UGT8,VPS35L,ADAMTSL3" MicroRNA hsa-miR-21:PITA hsa-miR-21:PITA_TOP PITA 1.43E-29 7.97E-26 4.09E-29 3.77E-28 59 263 "PTCHD1,CASKIN1,BCL7A,FUBP1,KRIT1,CFL2,SOCS6,CNOT8,CNTFR,ARHGAP24,SLC12A6,SNX29,RASGRP1,PLEKHA1,PAN3,SCML2,ST3GAL6,ANKFY1,CHL1,GABRG2,MSTN,FRMD3,RBPJ,IL12A,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MYO6,NELL2,PIK3R1,PPP3CA,MAPK10,TMEM260,RDX,PBRM1,AP1AR,SATB1,CPEB3,FBXO11,BTBD3,TET1,PDZD2,ITPRID2,MPRIP,PHLDB1,PLCB1,CAMTA1,ZFPM2,TIAM1,SGK3,VSNL1,TRIM9,TMEM237,RNF103,WNK3,NETO2" MicroRNA hsa-miR-1538:mirSVR_lowEffct hsa-miR-1538:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-29 8.03E-26 4.12E-29 3.79E-28 78 464 "ASPHD1,ADRA1B,AP2A2,AMPD2,PI16,PHYHD1,PPFIA3,CDK10,ARNTL,ATP2B2,RGS9,BMP7,DDR1,HIP1R,ARHGEF1,CDC25B,LY86,CCDC151,ZNF385A,ARHGEF10,ERC2,DAPK1,ELMO1,C2CD2L,ZNF582-AS1,SHANK1,DPH1,TOM1,SUGP2,EBI3,AMOTL2,FAM49B,PRELID3A,STAU2,BRSK1,PPARGC1A,STON1,ADAMTS13,GRIK5,BTN2A1,RNF165,AGBL5,ITPKA,LINC00634,KIT,CAMK2N2,CHST6,GIT1,CDK18,PLIN1,MAPK3,DUSP15,ARMC5,RPL15,TCP11L1,PTGR2,FNIP1,FOXRED1,SLC11A1,SNRPN,FNBP1,PEG10,DBNDD2,SSTR1,ST5,SMG6,CUX2,PIK3R5,WBP2,SMUG1,OSBP2,KLC2,UBE3B,CASC15,FAM219B,ADAMTS10,FAM198A,JPH3" MicroRNA hsa-miR-942:PITA hsa-miR-942:PITA_TOP PITA 1.67E-29 9.36E-26 4.80E-29 4.42E-28 65 323 "SPOP,PITPNM2,ATP2A2,CLCN3,QKI,HECTD1,COL4A5,CRY2,JAKMIP2,WDR20,CDON,CPEB2,EDN3,PHC2,PHF20L1,EGR3,PAN3,NRN1,ZNF589,SEC24B,FGF13,AFF2,C15orf41,CPLX1,TCERG1,CIT,HLF,AGFG1,HSF2,ZIC5,KCND1,MAT2A,MSI1,NEXMIF,ZC3H12B,NTRK3,PALM,PCDH9,XRN1,PPP2R5E,KANSL1,MAPK10,SNRK,PTPRD,BTBD3,CPEB4,SMARCA4,SOX11,ZBTB43,CLASP2,NECAB1,PLCB1,SYN1,FBXW11,ATMIN,WSCD1,ZEB1,THRA,TNS1,AMACR,FLRT2,PCDH20,HNRNPA3,MSRB3,SENP7" MicroRNA hsa-miR-210:mirSVR_lowEffct hsa-miR-210:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-29 1.03E-25 5.25E-29 4.84E-28 80 489 "ADD1,AP2A2,OSBPL1A,OSBPL6,C1QTNF3,MARCH4,LRFN1,CDK13,TMEM108,ADAM15,KSR1,BAIAP3,CBS,MTMR7,CACNA2D2,AKAP7,PCYT1B,FAM171B,CSF1,CSNK1E,USP6NL,HDAC4,SV2B,DNAJB6,YAF2,RCAN2,RAB9B,MRVI1,SEC24B,FGF13,FGFR1,SCARA3,FOXF2,FLNC,NOP56,IP6K3,ALDH1L1,ADAM28,GLYR1,STARD3,DCLK2,ZBTB49,RABL2A,FAM222A,MAN1B1,KIF5A,MAN2A2,MAPT,MBNL1,MEIS1,N6AMT1,ZNF862,DNHD1,OXTR,PCDH8,PCSK5,PDE3A,CCDC144B,PTPRD,SUSD4,CRTAC1,PRRT2,ATP8B4,MYO16,PDZD2,TROVE2,SEPT8,PRRC2C,ARC,CAMTA1,MGRN1,SIN3B,CLASP1,DICER1-AS1,ITGB3BP,AP4E1,PIK3R5,NDRG4,SLC38A1,KAT6A" MicroRNA hsa-miR-4268:mirSVR_highEffct hsa-miR-4268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-29 1.04E-25 5.31E-29 4.89E-28 85 549 "ACADM,ADD2,ADRB2,SUGT1P4-STRA6LP-CCDC180,NCOA1,RASL11B,ARHGEF7,DDR1,KALRN,CAMK2G,ZMYM4,PPT2,FAM149A,SMARCAL1,GDA,SNCAIP,PDE4DIP,DZIP3,BOC,GIT2,SGSM2,PHF20L1,KMT5B,PCOLCE2,ADGRV1,PRMT5,KAT8,POMT1,APOPT1,DISC1,AHDC1,TXNL4A,STARD3,CLASRP,FAM19A2,AGBL5,ZNF181,IGF1,RBPJ,IL6ST,MBD1,MITF,MYCN,NFE2L2,CNOT4,NOVA1,GLIPR1L2,PDZRN4,TRHDE,SEPT4,CEP41,MASP1,SAMD9,BDNF-AS,TMEM260,PTPRE,ACSM5,EXD2,NEK11,SCAF8,KANSL3,RCOR3,PDZD2,SP4,DBNDD2,ZNF302,ZC4H2,PRRC2C,TACC1,CAMTA1,ZEB1,FRYL,AP4E1,GALNT17,ARL10,TIAM1,TPM1,TPM2,AMACR,HSPBP1,RPL7L1,CCDC14,CFAP298,ZBTB38,NAV3" MicroRNA hsa-miR-1228:mirSVR_highEffct hsa-miR-1228:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-29 1.21E-25 6.20E-29 5.71E-28 81 502 "SYS1,ACTN1,CCDC85A,ADD2,DPP10,PHF12,PKP4,BCAS1,RGS20,ATP1B3,BID,BMP7,JAZF1,KALRN,SPAG9,L3MBTL4,SOCS6,IGDCC3,RNF14,ABCG1,CSNK1G3,PHF14,TBC1D5,DGKB,SGSM2,DNM1,ARRDC4,RASA4,ING4,TMEM35A,CALCRL,DENND4A,ZNF549,EYA1,RPS6KC1,FGF12,POMT1,ST6GALNAC3,GABRB3,C15orf41,DISC1,ADAM28,TCERG1,DCLK2,BVES,TNFAIP8L3,EID2B,MAT2A,THYN1,PAX6,PCDH9,PRTG,PFKFB3,ZNF655,ING3,PRKACB,SLC26A11,VPS13C,ZFHX4,SPIN3,CLIP1,SLC2A5,CPEB4,KDM4C,SS18,TTBK2,RGL1,SYN2,SYNE1,DOCK9,THRA,TPM1,TSC1,PLEKHH2,USP1,RBFOX3,XRCC4,EMSY,UBE3B,CASC15,JMJD1C" MicroRNA "ATACTGT,MIR-144:MSigDB" "ATACTGT,MIR-144:MSigDB" MSigDB 2.22E-29 1.24E-25 6.35E-29 5.85E-28 51 193 "SEMA6A,ANK2,ATP2B2,NRP2,CDH2,LHX2,QKI,PPP1R16B,PUM1,RHOBTB1,SNAP91,DMD,CPEB2,EIF4G2,EIF5,CALCRL,EPB41,ACSL4,ST6GALNAC3,GCNT2,CBX1,BACH2,HSF2,LIFR,NCOA7,MEIS1,MEIS2,MSI1,MYT1,NFE2L2,PDE4D,PFKFB2,PCDH18,PPARA,RIC8B,SEMA6D,SMPD3,CPEB3,FNDC3A,CCDC88A,SLC12A2,SP4,CDK19,SS18,FBXW11,RPGRIP1L,TRIO,NAV3,KAT6A,PHTF2,SENP7" MicroRNA hsa-miR-2909:mirSVR_highEffct hsa-miR-2909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-29 1.26E-25 6.41E-29 5.90E-28 76 444 "RALGAPA1,KLHL32,ADD2,KIAA1211,RNF150,HECW2,ALCAM,ABCD2,AMPD3,LCORL,ZFYVE28,ADAM23,RUNX1T1,LRBA,SRSF11,RGS6,RIMS2,ZBTB24,KLHL3,CHRDL1,WDPCP,RASGRP1,EGFR,AASS,MRNIP,EIF1,ERBB2,DLC1,SLC9B2,SEMA4D,AKAP3,SMC2,SARAF,AP4B1,MEGF11,GATM,TOX3,ZNF638,DCLK2,LNX1,SOX21,RASSF8,DHX35,KCND1,MAT2A,MBNL1,COL28A1,NRCAM,TBC1D25,GPR85,SEPT4,EPDR1,VPS13C,PTPRD,ZNF615,NWD1,MSANTD2,NUDT11,ATP8B4,NCBP3,KANSL3,MYO16,BDP1,NKAIN2,FBXW11,ZFP90,NAT16,PCDHB4,PUM2,SIK3,KAT6B,RUSC1,SSBP2,CELF4,CASC15,SOCS4" MicroRNA hsa-miR-498:PITA hsa-miR-498:PITA_TOP PITA 2.44E-29 1.37E-25 6.98E-29 6.43E-28 58 256 "MARCH4,NCOA1,C5,WASF1,CACNA1A,CAMK2G,LETMD1,CPEB2,PAN3,ERBB4,EYA1,FGF1,PRKAG2,CELF1,GABRB3,GATM,TCERG1,SPIN1,FERMT2,GRIA2,BACH2,MIER3,GABARAPL2,DHX35,KCND2,STXBP5,MATN3,LRP1B,MEIS1,KITLG,PDE4B,PIK3R1,CCSER2,PURG,PPP3CA,SNRK,PTCH1,PBRM1,NLGN1,BTBD3,WDR47,FAM214B,PKNOX2,ABTB1,TMCC1,SOX11,ITPRID2,LARP4,ANKRD28,DICER1,RIMBP2,TP53BP2,TSC1,RPRM,FLRT2,CADM2,EVI5,HNRNPA3" MicroRNA hsa-miR-622:PITA hsa-miR-622:PITA_TOP PITA 2.65E-29 1.48E-25 7.57E-29 6.97E-28 57 247 "AMPH,ATP1B3,PTBP2,LARGE1,FAM19A5,MAP4K4,APPL1,GAPVD1,IP6K1,ELMSAN1,CPEB2,EDNRA,HEYL,EYA1,NRN1,ANKFY1,MEGF10,PCDH17,GHR,RUNDC3A,GRIN2D,LINGO1,AGFG1,KCNB1,STMN1,MBNL1,NFYA,CLDN11,ZNF827,IRX1,MAPK3,PTK2,TMEM255A,SUSD4,KHDRBS2,FBXW7,SALL1,SATB1,CSRNP3,LRFN5,FNDC3A,FHOD3,CCDC88A,SOX11,ZSWIM8,POGZ,SS18,PLCB1,CAMTA1,RIMBP2,PDSS1,TRPS1,CCDC14,ZBTB14,SMARCAD1,SLC17A7,PHTF2" MicroRNA hsa-miR-1279:PITA hsa-miR-1279:PITA_TOP PITA 2.80E-29 1.57E-25 7.99E-29 7.36E-28 56 238 "BEND6,HECW2,CADPS,SYNJ1,SEPT7,CNTN1,PCYT1B,HAPLN1,RIMS2,ARHGAP24,DAPK1,DDX46,SACS,CPEB2,MBNL2,EGR3,RGS17,EMX2,ERBB4,PRKAG2,GABRB3,GABRG2,GPR162,FERMT2,MIER3,ELOVL5,IGF1,MBD1,MGAT3,MYO5A,NCAM2,NEFM,NEFH,NRCAM,NTRK3,CLDN11,CNTN3,PDE4D,PTK2,TMEM255A,RDX,WDR37,SOX11,PLCB1,SYT1,TCF12,DOCK9,AKTIP,SLC44A1,TRPS1,TSC1,UBE2H,LYPD6,EMSY,MSRB3,FXR1" MicroRNA hsa-miR-1909:mirSVR_highEffct hsa-miR-1909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-29 1.61E-25 8.20E-29 7.55E-28 83 528 "EMILIN3,ADD1,ADD2,PTCHD1,ZNF687,AMPH,LCORL,SPTBN4,RGS9,CA4,DDR1,P2RX6,CD86,RCBTB2,CBARP,MS4A7,PPT2,SLC35F1,ANKRD44,CS,GPSM1,CYBB,DAPK3,JAKMIP2,GSDME,PLPPR4,WDPCP,TSPAN5,KLHL5,GPHN,SRRM1,CLVS1,DLC1,FER,FGF1,FGFR1,BAIAP2,IP6K2,USP21,SDCBP2,GABRA3,TMEM8B,NTNG2,STMN2,GRM2,ELOVL5,ITPKB,MAN2A2,MARK1,MEIS1,P2RY1,PDE1B,ZDHHC8,SNX10,SMOX,SH3KBP1,KANSL1,MAPK4,FBXW7,KCNIP1,PEAR1,FHOD3,SLC9A5,DMRTC1,IFT122,SNRPN,ZC4H2,SULF2,SEPT3,NSFL1C,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,R3HDM1,NPDC1,HNRNPA3,ADAMTS10" MicroRNA hsa-miR-451:mirSVR_lowEffct hsa-miR-451:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.90E-29 1.62E-25 8.26E-29 7.60E-28 69 368 "PSMG3-AS1,SEMA6A,BCAS1,TNRC6C,WASF1,CALM1,CBLN1,CBR1,P2RX6,SCARB1,TIGD7,MYRIP,PREPL,ARHGEF10,SIPA1L1,PDE4DIP,MATR3,MAML1,IST1,GIT2,DNAL1,YTHDC1,SNAP91,SPOCK3,DMD,SEMA3D,PHF20L1,EVL,WDR83,DLL3,ZMAT1,GCNT2,TOX3,LUZP2,STMN2,BACH2,LRRC75A,SOWAHA,KIAA1755,IL6R,KIF2A,KTN1,LSS,NF1,OXTR,ENPP2,ING3,FA2H,MINDY2,TMEM231,FAM184A,CLIP1,LARP4,MPRIP,PLCB1,ASTN2,SATB2,ITGB3BP,AP4E1,SLC44A1,TSC1,UBE3A,KLC2,XPO1,ANKS1B,UPF3A,DHX33,GAL3ST3,NHSL1" MicroRNA hsa-miR-98-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.12E-29 1.75E-25 8.90E-29 8.20E-28 103 786 "ABCF1,ACADM,FZD9,MTUS1,AK2,ZNF578,SPARCL1,CDC42BPA,AQP6,IGDCC4,ARRB1,ZBTB10,BACH1,PPT2,CRY2,LRIG1,DOCK4,GAPVD1,DNAL1,ZBTB24,POM121,SACS,MTX3,USP3,DNAH9,ECM2,DUSP9,ABCC5,E2F5,E2F6,EDN1,ANKRD46,MBNL2,EIF4G2,GMPR2,SEC24B,TMEM164,IP6K2,NELFCD,TRMO,PDLIM5,CELF1,OGA,TRAF3IP2,DISC1,GATM,GCNT2,PPARGC1A,TCERG1,DBF4,RAB30,POLL,FUT10,GPR37,DIDO1,BTN2A1,RABL2A,IFI16,IGF1,IL6R,FAM69A,KPNA5,LIFR,MEIS1,MITF,THYN1,CNOT4,SLC11A2,NUCB2,OPRL1,NLE1,SCHIP1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,SEC31A,BTBD3,COA1,SMARCA4,PEG10,MCF2L2,ST5,PRRC2C,SYT1,KIAA0930,SLC19A3,NSD1,DICER1,CBX5,TNS1,SMUG1,PDSS1,TUBB2A,ZNF28,ZNF74,ZFAND5,SMARCAD1,FZD3,SOCS4" MicroRNA hsa-miR-7-5p:Functional MTI Functional MTI miRTarbase 3.28E-29 1.83E-25 9.33E-29 8.59E-28 87 578 "PLEKHH1,USP31,OSBPL8,ATP1B3,CFLAR,LDHD,ST3GAL5,AP1M1,ZNF555,HAP1,CBS,ENTPD6,CDC25B,PLEKHB1,CNOT8,TPP1,CNN3,ZNF385A,CNTNAP2,MATR3,PITPNC1,SPATA2,SNX29,PHC2,EGFR,C8orf37,MFSD10,ENPP6,MRPL10,DNAJC27,FGF1,CRCP,TNRC6A,GRIN2D,FICD,IDH3A,ZIC5,RBPJ,TJAP1,SLC35G1,KCNH2,GIT1,DBNL,NBL1,NFYA,CHAMP1,PAX6,PDE4D,ZNF655,PLEC,SLC25A23,MINDY2,MAPK9,NCR3LG1,PTK2,ERI2,ALG9,RPL15,GLDN,EMID1,SEMA6D,MRAS,KIF16B,CHD9,SIRT2,MYH15,ANKRD36,SNCA,FAM126B,SAMSN1,NXT2,ZC3H4,ADAMTS17,NSD1,CYB561A3,ZNF106,TLR4,RUSC1,TSN,HSPBP1,ZXDA,DNALI1,PRDM8,PARP11,RSPRY1,FXR1,GAN" MicroRNA hsa-miR-455-3p.2:TargetScan hsa-miR-455-3p.2 TargetScan 3.32E-29 1.86E-25 9.46E-29 8.71E-28 57 248 "ABR,RNF150,DYNLL1,EIF4G3,BCL7A,DST,FUBP1,CAMK2B,CFL2,CLCN3,ARMC8,COL4A5,NRG2,LIN54,CHRDL1,RAB39B,HIPK3,EGFR,EIF4G1,RCAN2,MPP6,CPLX2,CPLX1,CYP46A1,GLYR1,GPR75,AGFG1,NKD1,FAM69A,KCND2,HS6ST3,MYO9A,MYT1,NCAM2,NOVA2,NPTX1,OCRL,FAM216A,PRRT2,GTDC1,FIGN,KLHDC8A,ROBO2,RORB,RYR3,SATB1,CSRNP3,CPEB3,CCDC88A,NFASC,LMO3,PRRC2C,MMS19,FRYL,RPRM,RBFOX3,MAP3K12" MicroRNA hsa-miR-505-3p.2:TargetScan hsa-miR-505-3p.2 TargetScan 3.38E-29 1.89E-25 9.62E-29 8.85E-28 59 267 "GAS7,ARNTL,ATP2B2,CCNT1,C1orf52,CLCN3,FAM19A5,IGLON5,ARMC8,GDA,APPL1,CCDC144A,KIAA0408,MRO,PLXNC1,ENPP6,PIPOX,DNAJC27,CELF1,CPLX1,GCNT2,ARFIP1,CYP46A1,GHR,RNPS1,GPR75,GNAL,ATOH8,RASSF8,AGFG1,KCNN3,IPO5,CAMK2N2,MBNL1,KITLG,MXI1,PDE4D,PDPK1,NLE1,PLCL1,MAGEL2,PPP2R2C,GTDC1,FIGN,ROBO1,FAM192A,SALL1,BTBD3,EPN2,FAM126B,ARHGAP26,POGZ,MPRIP,ANKRD12,ERCC6L2,CLIP2,LYPD6,FZD3,CPNE4" MicroRNA hsa-miR-1289:mirSVR_highEffct hsa-miR-1289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.47E-29 1.94E-25 9.87E-29 9.09E-28 78 470 "SYS1,HFM1,SPOP,AMT,LCORL,PKP4,NT5C3B,SEMA4G,MADD,ARNTL,BACH1,CFLAR,SCAPER,C5,CA12,LURAP1,CALM1,KALRN,NFS1,ARHGEF2,RAB33A,FBXO7,VCAN,CST3,TMEM170A,DAPK1,BRINP1,DNAH9,SLC25A18,ABCC5,EDN3,PHC2,FCF1,AASS,TMEM35A,TLR7,KAT8,FER,POLK,WDR83,IQGAP2,DISC1,KIAA1841,PLPP7,MAN1B1,MAT2A,CCDC13,SMIM11A,TREM2,STRN3,PPP2R5E,CEP41,TMEM145,SUSD4,NUDT11,ARMC5,CARF,ELP2,R3HDM2,SMARCD3,SNAP25,MBD5,NMNAT2,PEG10,SYN2,DOCK9,CHST5,RUNDC3B,MEIS3,SLC30A4,SLC17A7,PDSS2,DNAH10,MARCH8,FBXO36,CASC15,RSPRY1,ZNF30" MicroRNA hsa-miR-346:mirSVR_highEffct hsa-miR-346:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.51E-29 1.97E-25 9.98E-29 9.19E-28 73 413 "ADD2,PWWP2A,KIAA1211,INTS2,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,FAM131A,LGR5,SPAG9,TIGD7,DGCR9,WHRN,SUMF2,SMARCAL1,RBM39,SNCAIP,PDE4DIP,RIMS2,ZNF337,DGKB,IP6K1,MYEF2,SGSM2,EXOG,FARSB,CHST15,PRKAG2,IP6K3,ALDH1L1,AP4S1,ZNF491,IRF8,ITPKB,LAMP2,NCOA7,MBNL1,KCTD6,THYN1,MYO9A,NF1,ALDH1L2,CLDN11,GPR173,SNX10,XRN1,MAPKAP1,SEPT4,PKIA,CNTLN,ZIK1,ZNF615,RDX,RGS4,RNASEL,NEK11,KCNIP1,KDM4C,ZNF423,RBM26,ZC4H2,ERBIN,ADHFE1,USP32P1,RGMB,TRIO,EIF4ENIF1,CCDC136,ZNF177,PCBP1-AS1,PLSCR4,HRASLS,CASC15" MicroRNA hsa-miR-516a-5p:mirSVR_lowEffct hsa-miR-516a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-29 2.12E-25 1.08E-28 9.91E-28 81 506 "ASIC1,SYS1,ELFN2,KIAA1211,OLMALINC,INTS2,CC2D2A,ALCAM,AMPD2,EPB41L5,PPP4R4,MARCH3,PTBP2,CAMK2G,MTMR7,ASIC3,FAM19A5,CNR1,AKAP7,LETMD1,ZFP28,RBM39,OSBPL3,RASGEF1C,CYBB,LYPD1,SV2B,DNM1,CD99L2,DPH1,CNNM1,FSD1L,KMT5B,IP6K2,NELFCD,UFM1,C15orf41,ZNF276,GPD1,TMEM121B,PLCD4,AP4S1,AGFG1,HSF2,CELF5,ZNF678,ITGAM,KTN1,LIMS1,PIK3AP1,MYO9A,NF1,CDK18,DUSP26,TMIE,ZNF655,PKD1,ANKRD16,SH3KBP1,PRKAB2,CNTLN,RGS4,DCUN1D2,TMLHE,RPS6KA2,SCP2,SLC14A1,ELMO2,OGDHL,ANKRD36,INAVA,CMTR2,DOP1A,TSNAXIP1,PLCB1,ITGB3BP,AKTIP,RPL7L1,SPIRE1,CIAPIN1,FXR1" MicroRNA hsa-miR-3147:mirSVR_highEffct hsa-miR-3147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.29E-29 2.40E-25 1.22E-28 1.12E-27 80 495 "KLHL32,SLC24A4,RTL9,ZNF687,AMT,PHF12,PKP4,PHYHD1,PPFIA3,CACNA1B,USP2,CLCN3,CRYBB1,CSF1R,CSF2RA,ERC2,KATNAL2,SV2B,KMT5B,VPS13B,EPHB1,TBC1D16,PPP1R1B,SLC9B2,AKAP3,ERAP1,TMEM8B,LRRC37A6P,GCK,TUBA8,PCDH17,BRD8,TNRC6A,MSL3,CCDC184,SLC2A6,KCND1,STMN1,MYO7A,MYO9A,P2RY13,IDNK,NF1,NUCB2,P2RX7,MASP1,PTK2,PTPRE,NUDT11,CARF,SNX22,NEK11,EPHA10,FBXW7,ZNF671,ATAT1,SARS,ARX,FAM214B,ELMO2,SPART,ATP10B,ZC4H2,SEPT8,ADHFE1,MTCL1,ZFP90,SIK3,ITGB3BP,AP4E1,TIAM1,CSMD1,NPL,FLRT2,BCL2L13,MDH1B,PDSS2,UBE3B,FXR1,GAN" MicroRNA "GCATTTG,MIR-105:MSigDB" "GCATTTG,MIR-105:MSigDB" MSigDB 4.85E-29 2.72E-25 1.38E-28 1.27E-27 47 163 "OGT,PHF12,NCOA1,ARHGEF7,KALRN,CAMK2G,CDH2,SOCS5,SLITRK5,KIAA0408,GOLT1B,PHF20L1,EIF4G2,COPS4,PAN3,ETV1,EXTL2,NSRP1,AMOTL2,NBEA,SPECC1,CELF1,GABRB3,GAD1,COPS8,GABARAPL2,IGF1,MEF2C,MXI1,PDE1B,GPR85,KANSL1,PTPN13,PTPRG,ZNF532,MRAP2,TRA2B,FNDC3A,CXXC4,FAIM2,SP4,TEX2,ARHGEF9,SATB2,DICER1,FLRT2,PRDM8" MicroRNA hsa-miR-1245:mirSVR_highEffct hsa-miR-1245:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.36E-29 3.00E-25 1.52E-28 1.40E-27 89 607 "KIAA1211,HECW2,PCDH10,LCORL,VAT1L,STK33,KSR1,CASTOR3,MTMR2,C5,RAB29,CDO1,RCBTB2,CLTC,QKI,AKAP7,ARHGEF10,VCAN,ZSCAN23,KIAA0586,ARMCX4,RHOBTB1,GOLT1B,PHF20L1,AASS,COPS4,EPB41L2,RCAN2,GPHN,PIPOX,ADGRV1,SUCO,SYNCRIP,ATP2C1,MSANTD4,SARAF,TRAF3IP2,KIAA1841,RAB40B,GRB10,GRIA2,DIDO1,SERP2,HMGCR,METTL21A,MOV10,ADAM22,NF1,NFE2L2,OCRL,PCSK1,PURG,MAPKAP1,WDR25,PIGG,TMEM260,TMEM255A,OXR1,RDX,ZMAT4,RET,ZC3H14,RTN1,SATB1,ATXN2,LRFN5,FNIP1,SH3GL3,CPEB3,FNDC3A,SLC2A5,IFT122,SP4,KDM4C,LMO3,SEPT3,TMEM150C,TBCEL,ITGB3BP,TMPO,FAM155A,UGT8,VLDLR,EML6,ADAMTS9,WNK3,FAM13C,RNF170,FRMD6" MicroRNA hsa-miR-3151:mirSVR_highEffct hsa-miR-3151:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-29 3.07E-25 1.56E-28 1.43E-27 84 545 "VWA5B2,AXIN2,SUGT1P4-STRA6LP-CCDC180,MADD,ARRB1,CHRD,KIF1A,CACNA1G,HAP1,CAMK2G,NFS1,CD86,ARHGEF2,ARHGAP33,LARGE1,NUMBL,CPNE6,NRXN3,CRMP1,USP6NL,KATNAL2,TCAF1,DRP2,MAMLD1,YAF2,TMEM35A,SIRPB1,F5,OLFM1,SPSB4,POMT1,SMC2,APOPT1,ZNF234,SULT1C4,GLI2,MAP7D2,GPD2,STMN2,PLCD4,CLASRP,AP4S1,ATXN2L,KCND2,LINC00634,MBD1,MEIS1,MEIS2,MYO7A,P2RY1,PRKAB2,RAP1GDS1,GTDC1,KIRREL1,NEK11,STK32B,NCBP3,COPZ1,PEX26,MBD5,CABCOCO1,KDM4C,ZC4H2,SEPT3,SYN1,ARC,MTCL1,CAMTA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,ZNF346,UBE3A,PLPPR2,LGI4,SLC17A7,FZD3,NLRP3,MSRB3" MicroRNA hsa-miR-1207-3p:mirSVR_highEffct hsa-miR-1207-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.91E-29 3.31E-25 1.68E-28 1.54E-27 94 672 "ASPHD1,AP2A2,CC2D2A,TAOK1,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,BCAS1,AQP6,ASPA,NCOA1,SEC11C,ARHGEF7,DDR1,ZMYM4,TIGD7,LETMD1,AHCTF1,SEC31B,SNCAIP,SEC24C,PHF14,GPRASP1,ARHGAP24,DCAF8,IST1,RAB39B,EDNRB,OPTN,PHF20L1,MBNL2,MRVI1,FDFT1,GORAB,GTF2IRD2,BAIAP2,RGPD5,PSD2,NBEA,GALC,SRCAP,CRCP,GLI2,GLUL,MAP7D2,GRIN2C,IRAK3,FRMD3,CELF5,ZNF678,AQP11,MOV10,SMIM11A,P2RX7,ETFRF1,PDE4D,PIK3C2A,PIK3R1,JAKMIP1,SH3KBP1,EPDR1,PID1,SLC25A48,RAD51D,MORC4,RPS20,SGK1,IFT122,ANKRD36,NMNAT2,ZNF423,ZC3H13,ZSCAN29,STX1A,SULF2,ANKRD28,CUX2,TPCN2,ARHGAP9,ITGB3BP,AP4E1,SLC44A1,BHLHB9,TP53BP2,TPM1,CLHC1,PLEKHH2,CLDND1,RICTOR,CFAP298,EMSY,PCBP4,MPPE1,PARP11,CASC15" MicroRNA hsa-miR-941:mirSVR_lowEffct hsa-miR-941:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.29E-29 3.52E-25 1.78E-28 1.64E-27 90 621 "FGD2,APBA2,FAM131A,MADD,STX16,RIPK1,ADAM23,ADAM15,BACH1,MPDZ,HAP1,PTBP2,RGN,CBFA2T2,MAP4K4,IQCK,COL4A5,COX4I1,MYRIP,HINFP,ARHGEF10,UBXN2A,GREB1,CYBB,HDAC9,MYADM,KATNAL2,ZFYVE16,TM9SF4,DPP6,ECM2,KRBA2,PHC2,FCF1,TMEM132E,ELN,HSD17B14,EZH1,POLR1B,MEX3B,IP6K2,ZNF605,ERGIC3,FAM120B,TUBGCP4,GGT7,PPARGC1A,ZNF276,GNG4,PLCD4,GRIN2D,BTN2A1,RASSF8,FRMD3,HMGCL,ZNF491,INPP5B,NME9,GATD1,MAP4,ZNF655,CNNM2,TMEM231,ACSS3,UBR7,RGS12,ABCA11P,SH3BP2,FERMT1,MYO18A,R3HDM2,SLC9A5,MAST1,IFT122,ZC4H2,ST5,DIP2A,KIAA1107,SIN3B,SYNE1,OBSL1,TNS2,TIAM1,ACTR6,C9orf85,CHST5,OSBP2,FLRT2,POLR3H,DHX33" MicroRNA hsa-miR-150-5p:Functional MTI Functional MTI miRTarbase 6.44E-29 3.60E-25 1.82E-28 1.68E-27 83 534 "AS3MT,XKR4,RNF157,PWWP2A,PTCHD1,ZNF578,PHF12,CDC14B,ARRB2,ARSE,ATP1B3,ZNF582,LDHD,VXN,CAST,ZBED1,DIS3L,PLAA,ENTPD4,CSNK1E,SOCS5,DNAL1,TOM1,IRAK4,C8orf37,MTSS1L,SLC43A2,MRPL37,TLR7,TBC1D16,AMOTL2,IP6K2,ANKFY1,APOPT1,TRAF3IP2,RAPGEF6,KIAA1841,SRCAP,CRCP,RNF165,HAS2,NKD1,SLC35G1,METTL21A,KCNK3,MBD1,NFYA,P2RX7,TMOD2,PIK3C2A,SMIM7,ZNF426,CNNM2,ZSCAN2,ZNF844,C12orf49,PGBD4,SCN2B,HSPA4L,KANSL3,BDP1,ZHX3,SP2,STAC2,KLHL7,AGTPBP1,KIAA0930,ZEB1,GPRIN3,ZMAT3,CBX5,PARD3,SYNPO2,SMUG1,RUNDC3B,TRPS1,TSPAN11,LAT2,ZNF708,ZNF70,DPYSL5,MPPE1,GAN" MicroRNA hsa-miR-1827:PITA hsa-miR-1827:PITA_TOP PITA 7.27E-29 4.07E-25 2.06E-28 1.89E-27 58 261 "ASIC1,XKR4,SEMA6A,EIF4G3,JAZF1,LDLRAD4,CALB1,THSD7A,CAMK2A,CAMK2B,CAMK2G,FAM19A5,MAP4K4,CNN3,PICK1,LETMD1,MYRIP,ELMSAN1,ABCC5,CELSR3,SLC43A2,CORO2B,IQGAP2,GPR162,GPD2,PCLO,BACH2,IGF1,ZIC5,IBA57,INSM1,KCND2,KTN1,NCOA7,CHIC1,ZNF827,ANKRD16,SCHIP1,RETREG2,SH3TC2,SETD5,CYB561D1,SCP2,CPEB3,RCOR3,NMNAT2,ASTN2,MTCL1,MCF2L,TCF4,KIAA0930,HEY1,CBX5,NR2E1,DOK6,KCNE5,CCDC136,ZIC1" MicroRNA hsa-miR-3199:mirSVR_highEffct hsa-miR-3199:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.38E-29 4.13E-25 2.09E-28 1.92E-27 79 487 "VWA5B2,USP35,DPP10,USP37,PPP4R4,ARHGEF7,HAP1,CERS5,USP6,AP4M1,L3MBTL4,TAOK2,EPS15L1,CLCN3,STOML1,RAB26,CNGA3,CNTFR,LETMD1,TBPL1,NECTIN3,CST3,PHF14,CCDC144A,RIPOR2,HEPH,ACOT8,ARRDC4,TOM1,VPS13B,RCAN2,CEP85L,CHST15,ZNF589,NELFCD,ATP2C1,FYB1,SRCAP,GHR,GLI2,PCLO,C1QL4,ZBTB49,SYNPO,FAM95B1,LRRCC1,ZNF678,A1BG-AS1,MAP4,MARK1,MBNL1,MPP2,COMMD5,PDCD2,PFKFB2,HYDIN,ZSCAN2,RFX2,RGS3,ATAT1,PPP4R3A,EPN2,SLC8A1,SMARCD3,ANKRD36,SP4,HECW1,CLASP2,ST5,SULF2,SEPT3,VPS13A,KIAA1107,SATB2,FRYL,HIF3A,MTMR14,EML6,DPF3" MicroRNA "CACTTTG,MIR-520G:MSigDB" "CACTTTG,MIR-520G:MSigDB" MSigDB 7.53E-29 4.21E-25 2.13E-28 1.96E-27 54 224 "APBB2,USP37,MARK4,ATP2B2,ADGRB2,JAZF1,CFL2,SOCS6,CNR1,PCYT1B,ARMC8,AHCTF1,DCAF8,DBN1,DMD,DMTF1,DNAJB6,CELSR3,KMT5B,GOLGA7,EIF4G2,PTK2B,GTF2IRD2,NBEA,MSANTD4,OGA,TCERG1,TNRC6A,MAT2A,MYCN,PPP3CA,MAPK9,PTPN13,SALL1,CHD9,FNDC3A,ITPRID2,PLCB1,TBL1X,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TRPS1,FLRT2,VLDLR,DPYSL5,SLC30A3,EMSY" MicroRNA "CACTTTG,MIR-520H:MSigDB" "CACTTTG,MIR-520H:MSigDB" MSigDB 7.53E-29 4.21E-25 2.13E-28 1.96E-27 54 224 "APBB2,USP37,MARK4,ATP2B2,ADGRB2,JAZF1,CFL2,SOCS6,CNR1,PCYT1B,ARMC8,AHCTF1,DCAF8,DBN1,DMD,DMTF1,DNAJB6,CELSR3,KMT5B,GOLGA7,EIF4G2,PTK2B,GTF2IRD2,NBEA,MSANTD4,OGA,TCERG1,TNRC6A,MAT2A,MYCN,PPP3CA,MAPK9,PTPN13,SALL1,CHD9,FNDC3A,ITPRID2,PLCB1,TBL1X,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TRPS1,FLRT2,VLDLR,DPYSL5,SLC30A3,EMSY" MicroRNA hsa-miR-140-3p.2:TargetScan hsa-miR-140-3p.2 TargetScan 8.75E-29 4.90E-25 2.47E-28 2.28E-27 67 353 "PTCHD1,AP2A2,PCDH10,ANK2,PHF12,CCAR2,ATP2A2,ATP2B2,LDLRAD4,RUNX1T1,FHL5,NSL1,PITPNM3,PYGO1,HDAC4,DGKG,IP6K1,DNM1,DRP2,HIPK3,CELSR3,PLXNC1,MED12L,FGF12,HPCAL4,KHDRBS3,CELF1,CHL1,AHDC1,PCDH17,RAB30,GLUL,GPR12,GRM2,KAT7,MIER3,HLF,KCNB1,KIF2A,KIF5A,CHIC1,MEIS2,KCTD6,MMP16,NFYA,NNAT,NOVA1,PCDH8,PDE3A,OLA1,SCHIP1,KANSL1,RASGEF1B,PTCH1,KHDRBS2,ARMC5,ROBO2,FBXW7,ATF7IP,DDN,NKAIN2,SATB2,DOCK9,RUSC1,GDPD5,HNRNPA3,GAN" MicroRNA hsa-miR-1301:PITA hsa-miR-1301:PITA_TOP PITA 9.01E-29 5.04E-25 2.54E-28 2.34E-27 58 262 "NDRG3,USP31,BEND6,DPP10,MAP4K3,CDK13,SRSF11,CHN1,PHACTR3,CHRDL1,HIPK3,TENM1,ENO2,OLFM1,SUCO,MEGF11,GABRB3,PPARGC1A,GPD2,CIT,BACH2,MBNL1,MSI1,NBL1,ZC3H12B,NFIX,NPTX1,ZNF827,PDE4D,OLA1,PIK3R1,ROBO2,RASA3,MYO18A,FBXO11,RCOR3,HECW1,ERC1,PEG10,CLASP2,ELOVL4,SULF2,CAMTA1,TCF4,SATB2,SZT2,TNS2,FRYL,SIRT1,RIMBP2,CSMD1,NR2C2,ZBTB14,TRIM9,POLR3H,EMSY,SLC17A7,HNRNPA3" MicroRNA hsa-miR-517c:mirSVR_lowEffct hsa-miR-517c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.56E-29 5.35E-25 2.70E-28 2.48E-27 71 397 "OGT,CCDC146,PKP4,KCNAB2,APBB2,TNRC6C,PPFIA3,LGR5,EIF4G3,CFLAR,KALRN,USP6,ARHGEF2,DGCR9,FAM189A2,HECTD1,GALNT9,DOCK4,MATR3,KCTD8,DAPK1,JAKMIP2,LYPD1,SV2B,DTNA,C3orf18,ENPP6,PTK2B,FLT1,EFCAB2,DISC1,COPS8,FERMT2,RNF165,NKD1,SLC35G1,A1BG-AS1,SAMD5,P2RY13,OXTR,PFKFB4,SEMA5B,PPP2R2C,EPDR1,MAPK9,PTPRH,PTPRO,RASGRF2,UBR7,RGS12,KCTD17,LGI2,C12orf49,SHC4,SLC12A2,RCOR3,SNRPN,DIP2A,STXBP1,UGT8,TBC1D15,SLC47A2,CELF4,STOX2,PRDM8,RNF103,ADAMTS9,MPPE1,WNK2,EPM2A,ACTR3B" MicroRNA hsa-miR-1179:PITA hsa-miR-1179:PITA_TOP PITA 1.01E-28 5.64E-25 2.84E-28 2.62E-27 57 253 "TMEM132B,CCDC85A,RNF150,ZNF608,PCDH19,LRCH2,WASF1,CACNA2D1,THSD7A,CHGB,B4GALT6,SLIT2,CS,DZIP3,ERC2,APPL1,HDAC4,DNAJB6,PLEKHA1,CALCRL,FGF11,KHDRBS3,GABRG2,PPARGC1A,GNAO1,GRIA2,FAM19A2,RNF165,MIER3,BLOC1S2,NEXMIF,NRCAM,GPR137C,PTCH1,PTPRB,PTPRO,GTDC1,ATXN2,CPEB3,TET1,SNAP25,MBD5,CDK19,CLASP2,NKAIN2,PLCB1,CAMTA1,TCF4,FRYL,SLC44A1,NR2E1,TSC1,ZIC1,ZBTB38,CADM2,WNK3,TMEM63C" MicroRNA hsa-miR-324-3p:mirSVR_highEffct hsa-miR-324-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-28 6.12E-25 3.08E-28 2.84E-27 83 538 "GALNT16,CDC42BPA,PI16,PPP4R4,ARRB1,STK33,DNAH17,DPY19L3,SYNJ2,ARHGEF7,LRBA,LRRFIP1,PPT2,COX4I1,CRMP1,ABCG1,SEC24C,GREB1,ZSCAN23,DCAF8,YTHDC1,DDX46,DPP6,WDPCP,EDN3,FCF1,KLHL5,FRY,PHF20L1,EPHB1,SCML2,ZSCAN30,FDFT1,IP6K2,EFCAB2,WDR83,TRIM16,CGREF1,OGA,GABBR1,NEU3,DCLK2,PLCD4,AP4S1,RNFT2,FAM95B1,SOWAHA,KIF5A,MXI1,LYRM9,SETD4,ZNF827,PIK3R1,PNMA3,PPP5C,CNTLN,MTMR10,STK32A,ZCWPW1,RGS4,ZNF532,TMLHE,NEK11,SCN8A,COPZ1,HKDC1,CNKSR2,FAM214B,SLC9A5,HECW1,TEX2,DBNDD2,TSPYL2,SS18,TBCEL,THRA,ELP5,ZBTB14,ZNF711,INTS3,DNALI1,WNK2,HNRNPA3" MicroRNA hsa-miR-1202:mirSVR_highEffct hsa-miR-1202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-28 6.12E-25 3.08E-28 2.84E-27 83 538 "ACADM,PTCHD1,MAP4K3,TTLL9,GYG2,CLDN10,LARGE1,NUMBL,NRXN3,SULT4A1,CREM,PPP6R2,BOC,DAPK1,ARMCX4,FBXL5,KIAA0753,KIAA0319,ZC3H11A,DDX46,SV2B,DMTF1,ECM2,DNAJB6,AASDH,EPB41L2,ADGRV1,TAOK3,SEC24B,FLT1,ATP2C1,SARAF,ZNF234,ERAP1,SULT1C4,SESN1,PCDH17,COPS8,ZNF638,WDFY3-AS2,FUT10,CLASRP,MSL1,IL6ST,JAK2,PAXBP1,TM6SF1,LYRM9,RETREG1,PPP3CA,PRKAB2,PRKCB,FAT4,RBBP6,ZFHX4,SPIN3,ZC3H14,MCMBP,ABCA11P,SYBU,ARHGEF40,ZFP1,SMARCA4,IFT122,DOK5,SSPO,ADHFE1,STXBP1,SYNE2,TMEM150C,PUM2,PCDHA5,HIF3A,MTMR14,TPM1,SYNPO2,CLHC1,ZNF610,WRN,KCNT2,FTSJ1,LAMP5,FAM219B" MicroRNA hsa-miR-195-5p:Functional MTI Functional MTI miRTarbase 1.17E-28 6.55E-25 3.30E-28 3.04E-27 91 639 "AXIN2,FZD9,USP31,CASKIN1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,CASK,ARHGDIA,ZBTB10,DOCK11,BCL7A,MTMR3,CA8,RUNX1T1,CCNT1,ENTPD6,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,DMPK,USP3,CPEB2,DMTF1,FCF1,HEYL,PLEKHA1,ELN,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,MSANTD4,RNPS1,RAB40B,GNAL,NEGR1,MSL1,NKD1,RBPJ,JAK2,LAMP2,MBD1,CHIC1,SCAMP5,MYO5A,OCRL,ETFRF1,PDE4D,PIK3R1,PSAT1,RASGEF1B,PTPRD,RBBP6,RET,ZFHX4,RNH1,SALL1,HSPA4L,KIF21A,CPEB3,ANKRD36,KANK1,PRRC2C,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,TPM2,NR2C2,TUBB2A,UBE2H,WNT7A,KLC2,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-4308:mirSVR_highEffct hsa-miR-4308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-28 7.09E-25 3.57E-28 3.28E-27 78 479 "LRFN2,MTUS1,RTL9,SPOP,OGT,NT5C3B,DPY19L3,NRP2,GYG2,KALRN,CLDN10,ZMYM4,LRRFIP1,ARMC8,SLC4A8,ABI3BP,ANKRD44,CST3,GPRASP1,KIAA0586,DBN1,RHOBTB1,FAM13A,EGFR,EPB41L2,SRRM1,EXTL2,FAM198B,FGF14,FGFR1,BAIAP2,SPECC1,CELF1,TMEM8B,FERMT2,TDRKH,FUT10,KAT7,PSIP1,NCKAP1L,SMAP1,SOWAHA,KIF5A,SRSF12,NRBP2,SLC11A2,NTRK3,VPS13C,STRC,RAD51D,GTDC1,MRPS18A,CARF,PCMTD2,TRA2B,CHD9,SEPHS1,BTBD7,ATF7IP,SOX3,SP4,NFASC,MPRIP,AGTPBP1,FBXW11,PCDHB3,TK2,RGMB,TSC1,GORASP1,SLC47A2,EMSY,PRDM8,URM1,SLC17A7,PDSS2,MSRB3,SPATA13" MicroRNA "TCCAGAG,MIR-518C:MSigDB" "TCCAGAG,MIR-518C:MSigDB" MSigDB 1.33E-28 7.46E-25 3.75E-28 3.45E-27 44 143 "PCDH19,ANK2,PRX,PCDHGB4,ATP2A2,CAMK2G,TMEM184B,NCOR2,PUM1,GOLGA7,TNK2,MED12L,GAD1,MSTN,TCERG1,BACH2,MEIS2,MKLN1,NFIX,PCDHGC3,PCDH9,SDK2,ING3,SEPT4,CCDC144B,GTDC1,SMPD3,CUX2,RPGRIP1L,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,RICTOR,SLC30A4,ST8SIA2" MicroRNA hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 1.39E-28 7.76E-25 3.90E-28 3.59E-27 66 345 "KCNH8,MARCH3,INSYN2B,N4BP2L1,DST,CACNA1A,CALM1,ARHGEF1,QKI,HECTD1,NRG2,CSNK1G3,DAPK1,JAKMIP2,RPS6KL1,CPEB2,DOCK2,DTNB,EBF1,PAN3,MRVI1,CORO2B,FGF1,MEX3B,CAMKK2,ALDH1L1,GHR,GPD2,PTPRT,KAT7,FRMD5,HMGCR,MSL1,IL6R,KCNB1,KCND1,LIFR,NCOA7,AFF1,MYO6,NOVA1,NOVA2,LRP12,RASGEF1B,MAPK4,MAPK7,CNNM2,APTX,QDPR,FIGN,CYB561D1,SCN2B,HSPA4L,SCAF8,PPM1E,ASAP3,ARHGEF40,ARHGAP26,CLASP2,LARP4,PHLDB1,ANKRD12,CBX5,KLC2,RICTOR,PHTF2" MicroRNA hsa-miR-411:mirSVR_highEffct hsa-miR-411:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.42E-28 7.97E-25 4.00E-28 3.68E-27 83 540 "TMCC3,ALCAM,ABCD2,DPP10,MAGEE2,NT5C3B,WASF1,CALM1,PTBP2,CAST,ZBED1,CDH2,LRRFIP1,CCPG1,CHGB,NRXN3,CLTB,SULT4A1,COL4A5,MAGED1,PREPL,RNF14,CSNK1E,VCAN,PDE4DIP,APPL1,PUM1,ZSCAN23,TCAF1,FBXL5,CHRDL1,PDCD6IP,FRY,EIF4G2,TUBB3,ZSCAN30,UBE2E3,ATP2C1,ABLIM2,FYB1,ZMAT1,GCNT2,DBF4,GNAO1,GPD2,CCDC184,MSL1,ZNF680,PDCD2,OLA1,ZFYVE21,PPM1B,SAMD9,C1orf109,OXR1,RET,EXD2,SPIN3,ABCA11P,ATXN7,FERMT1,ELMO2,GKAP1,MAPKBP1,SP2,SP4,PBLD,CLSTN2,DMXL2,SYNE1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,CLHC1,ELFN1,WNK3,NHSL1" MicroRNA hsa-miR-596:mirSVR_highEffct hsa-miR-596:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-28 8.15E-25 4.09E-28 3.77E-27 63 314 "ACADM,APBA2,ZFYVE28,CNRIP1,CREM,GDA,PDE4DIP,ERC2,CYBB,FBXL5,SGSM2,FAM107B,CHRDL1,DPYSL2,DTNB,EDN1,C3orf18,GMPR2,PCYOX1,ATP13A4,FLT1,C15orf41,GRIA2,PLCD4,ADAMTS13,ELOVL5,HMGCR,MSL1,DISP2,LMO2,HECTD2,COL28A1,NRBP2,NEK1,NTRK2,P2RY1,CNTN3,PLIN1,SMIM7,ING3,GRAMD1C,CNTLN,PTPRG,CARF,ATAT1,SUPT20H,ATF7IP,ANKRD36,SNRPN,SP4,TTBK2,NSFL1C,VPS13A,FRYL,ARL10,BHLHB9,ELP5,WIPF1,ZSCAN26,MRPL47,KLHDC1,AP3B2,ST8SIA2" MicroRNA hsa-miR-128-3p:Functional MTI Functional MTI miRTarbase 1.46E-28 8.19E-25 4.11E-28 3.78E-27 82 528 "ACADM,ADD1,FZD9,PTCHD1,INTS2,TAOK1,GAS7,RNF182,AZGP1,HIP1R,CCNT1,ZNF385A,ABCG1,CSF1,RGS6,PHF14,PYGO1,BOC,LONRF1,LIN54,SEC16A,NR1D2,EGFR,KMT5B,EIF5,EPHB1,DNAJC27,POLR1B,SUCO,ANKFY1,NBEA,FAM49B,FYN,HRASLS5,GCNT2,TPPP,KAT7,MIER3,C2orf72,IGF1,ZIC5,SLC6A17,KLHL23,LIFR,MKLN1,MPP2,BLOC1S2,MYO9A,NTRK3,PDE3A,PDPK1,PIK3R1,PKD1,PDZRN4,SDK2,RETREG2,RELN,CNNM2,VPS13C,SNRK,RET,RFX3,ZFHX4,FBXW7,RXRA,CASC3,R3HDM2,CPEB4,ZFP1,FNBP1,SOX11,PEG10,SPTAN1,CDK19,TROVE2,ITPRID2,MPRIP,FRYL,SIRT1,ARL10,WRN,RICTOR" MicroRNA "ACTTTAT,MIR-142-5P:MSigDB" "ACTTTAT,MIR-142-5P:MSigDB" MSigDB 1.47E-28 8.23E-25 4.13E-28 3.80E-27 59 274 "RALGAPA1,ALCAM,GAS7,SLC4A4,ADGRB3,SYNJ1,CAMK2A,TAOK2,CLCN3,QKI,C2CD2,FAM131B,SPOCK2,SACS,FAM107B,CPEB2,EGR3,ETV1,MED12L,FGF13,LUZP2,RNF165,BVES,IGF1,KIT,LRP1B,KITLG,MKLN1,MYCN,NFE2L2,NTRK3,ZFYVE21,RETREG1,LRP12,RETREG2,CEP97,RBBP8,REV3L,FIGN,RIC8B,RNH1,ROBO1,RTN1,CPEB3,CHD9,FNDC3A,ARHGEF40,BTBD7,CPEB4,MBD5,SP2,CAMTA1,ADGRL3,TCF12,ZFPM2,SLC17A7,JMJD1C,NETO2,ST8SIA2" MicroRNA hsa-miR-32-5p:Functional MTI Functional MTI miRTarbase 1.48E-28 8.30E-25 4.16E-28 3.83E-27 85 565 "CASKIN1,OSBPL8,FAM135A,ATP2A2,DST,SYNJ1,TMEM184B,HECTD1,APPL1,EARS2,LIN54,SPOCK2,GIT2,DBT,SPATA2,CPEB2,ARRDC4,MRO,KMT5B,PLEKHA1,RGS17,EIF1,DNAJC27,PRMT5,SLC37A3,USP21,GAA,GLYR1,KIAA1958,PRRC2B,FUT10,LILRA2,TPPP,ZHX1,MIER3,HMGCR,AGBL5,EID2B,ZIC5,RBPJ,IL6ST,LAMP2,PIK3AP1,MYO5A,CNOT4,CCSER2,SNX10,ZFYVE21,XRN1,PURG,TATDN3,MTMR10,REV3L,SLC25A36,SETD5,FBXW7,FNIP1,CPEB3,SYBU,ZNF430,ATF7IP,CPEB4,FAM126B,SOX11,TEX2,MCF2L2,PBLD,ITPRID2,ERBIN,TACC1,AGTPBP1,DOCK9,TRIO,TSC1,SGK3,ZNF17,ZNF24,ZXDA,MFF,EVI5,RNF103,PHTF2,NHSL1,FXR1,GAN" MicroRNA hsa-miR-342-3p:Functional MTI Functional MTI miRTarbase 1.51E-28 8.46E-25 4.24E-28 3.90E-27 62 304 "KCTD16,BMP7,CRLF1,LETMD1,PLXNA4,HDAC9,LONRF1,TM9SF4,HIPK3,EGR3,ASB3,EPB41,POLR1B,CBX1,FAM107A,FRMD3,USP51,IDH3B,C2orf72,TJAP1,LSAMP,SHC3,PPM1L,MXI1,ZC3H12B,KCTD15,MTRF1L,STRN3,PSAT1,APTX,PTPRN2,FIGN,RFX3,RGS4,TMLHE,RPL15,HUNK,ATXN7,GALNT10,CPEB3,CHD9,ZNF430,SEPHS1,CPEB4,MAPKBP1,KIF13A,TRERF1,ERC1,NFASC,ZSCAN29,DNAJC9,SYT5,TACC1,TAL1,TIAM1,BHLHB9,ZNF610,UBE2H,UBTF,CRB2,ZDHHC20,NETO2" MicroRNA hsa-miR-500:PITA hsa-miR-500:PITA_TOP PITA 1.65E-28 9.25E-25 4.63E-28 4.27E-27 64 325 "HECW2,PCDH19,ZFYVE28,SLC4A4,FUBP1,QKI,RCHY1,CS,ERC2,RIMS2,YTHDC1,DDX46,CASP8AP2,PCOLCE2,CALCRL,ERBB4,EYA1,DLC1,FGF12,PRKAG2,DCTN2,ATP6V1H,FUT9,C15orf41,CIT,RNF165,HAS2,MIER3,NEGR1,MBNL1,LRP1B,AFDN,GPR85,XRN1,SMOX,STRN3,PPP2R5E,PTPRD,TMEM145,RDX,ZMAT4,FIGN,RFX3,ROBO2,SATB1,CASC3,ST6GAL1,PKNOX2,CCDC88A,SLC12A2,RCOR3,SOX11,CDK19,LARP4,ERBIN,SYN1,ANKRD12,SATB2,RPGRIP1L,UBE3A,ZIC2,MICU3,ZBTB38,TMEM178A" MicroRNA hsa-miR-3130-5p:mirSVR_highEffct hsa-miR-3130-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-28 9.36E-25 4.68E-28 4.31E-27 82 529 "ASIC1,PCDH10,LGR5,MARK4,DPY19L3,SPAG9,DGKI,TIGD7,MYL6B,AKAP7,SLC35F1,AKAP12,ANKRD44,CS,PITPNM3,LIN54,B3GAT3,DNAJB6,HIPK3,PHF20L1,COQ7,CDKL3,F5,ZSCAN30,FER,AMOTL2,PDLIM5,CELF1,STAU2,KIAA1841,TUBGCP4,ADAM28,GHR,DCLK2,GPD2,PSIP1,HAS2,MIER3,HMGCL,STMN1,MARK1,MEIS2,ZNF680,MYCN,MYO9A,FAM218A,CCSER2,DRAM2,PPM1B,PRKACB,PTCH1,TMEM260,EML5,PPP2R3C,RAD51D,MRPS18A,CCDC82,RORB,ELP2,RPE,ARMH4,ABCA11P,SCP2,FHOD3,R3HDM2,CNKSR2,ZKSCAN3,USP33,POGZ,SYNE2,PLCB1,PCDHB10,FRYL,CCDC173,ARL10,HEY1,KCNE5,GUSBP1,HPS4,NAV3,WNK3,FBXO36" MicroRNA hsa-miR-103-as:mirSVR_highEffct hsa-miR-103-as:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-28 1.01E-24 5.04E-28 4.64E-27 76 458 "PTCHD1,MTUS1,HACE1,BEGAIN,PHF12,SUGT1P4-STRA6LP-CCDC180,NUMB,ATP1A1,TTLL9,CFLAR,ZNF501,HECTD1,FAM171B,RBM39,CS,RGS6,MAML1,DDX46,ALKBH8,PDCD6IP,PHF20L1,KCTD3,RGS17,RGPD5,PSD2,NBEA,RASL10A,KIAA1841,GHR,BRD8,CCDC184,CNTRL,GRIA2,RASSF8,HMGCL,IDH3B,KCND2,KCNJ16,KIF2A,SMAD1,ZNF667-AS1,MAT2A,AQP11,GNG2,PPARA,GRAMD1C,RELN,VPS13C,SNRK,BDNF-AS,ZCWPW1,RDX,SNX22,NEK11,GLDN,SAFB,SATB1,TNFRSF19,SHC4,HKDC1,FNDC3A,EPC1,SNAP25,ITPRID2,ZSCAN29,PRRC2C,CAMTA1,CUX2,TRIM2,RPGRIP1L,MTMR14,TPM2,KCNT2,PDSS2,MRPL47,JMJD1C" MicroRNA hsa-let-7e*:mirSVR_lowEffct hsa-let-7e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-28 1.08E-24 5.42E-28 4.99E-27 57 256 "RALGAPA1,ZNF608,MIR9-3HG,DST,NAE1,ISPD,PRC1,B4GALT6,ZFP28,SLC35F1,CASP8AP2,DNAJB6,ABCC5,DNM1L,EDNRA,EGFR,EYA1,ARMCX1,ABCA8,SH3YL1,CORO2B,ANKFY1,FOLH1,TRMO,IQGAP2,GATM,ZNF638,PCLO,GRB10,GRIA2,ELOVL5,CFAP126,LRRCC1,INSM1,METTL21A,MYO9A,NEK1,NOVA1,KCTD15,KANSL1,PRKACB,GRAMD1C,ZSCAN2,UBR7,ATAT1,SATB1,PPM1E,HKDC1,FNDC3A,TBL1X,ATMIN,KCNE5,VIPR2,GUSBP1,XRCC4,ZNF24,DPYSL5" MicroRNA hsa-miR-769-5p:mirSVR_highEffct hsa-miR-769-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-28 1.13E-24 5.64E-28 5.19E-27 84 555 "KCNH8,PTCHD1,FAHD2CP,C1QTNF1,CFLAR,SYNJ1,CLDN10,LDB2,RCBTB2,RGS6,APPL1,IST1,GSDME,E2F5,CNNM1,FSD1L,KMT5B,CERCAM,DCTN4,CEP78,FER,SLC37A3,ZMAT1,RAPGEF6,SIGLEC8,DISC1,KIAA1841,NEU3,GRIA2,ZNF496,CIT,ZBTB49,ADAMTS6,SYNPO,TCEAL6,SMAP1,FAM95B1,NME9,SMAD1,CLEC18A,LYPLAL1,MBD1,TAGLN3,RTL5,VWA2,DNHD1,NTRK3,P2RY1,PCDH9,PCSK5,DUSP26,PLCL1,LRP12,POLR2F,GRAMD1C,HYDIN,SAMD9,CYBC1,TMEM260,SH3TC2,CCDC102B,S100B,SGK1,AMBRA1,ANKRD6,KANSL3,SLC22A4,ZNF415,ADHFE1,WSCD1,USP32P1,HEY1,RIMBP2,TPM1,TRIO,RUSC1,TSC1,TBC1D15,TCEAL7,SMARCAD1,SLC17A7,EPM2A,RGS7BP,SMIM8" MicroRNA hsa-miR-1260:mirSVR_highEffct hsa-miR-1260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-28 1.17E-24 5.82E-28 5.36E-27 90 631 "NCKAP5,BRAP,AK2,CDC42BPA,PARG,ZNF582,SLC2A11,SYNJ2,PTBP2,CD86,CDH2,SOCS6,RAB28,HECTD1,LETMD1,MYRIP,RNF14,GDA,SIPA1L1,ZFYVE16,ZNF337,TBC1D5,DBI,DBN1,HS3ST2,DMTF1,EPB41,RABEPK,STX2,ZNF391,HSPA12B,FCGRT,FER,GTF2IRD2,FGFR1,SUCO,FOXF2,IQCG,SLC37A3,TMEM107,UFM1,NSG1,IQGAP2,DISC1,NEU3,SRCAP,SULT1C4,MSL3,ZNF638,TDRKH,LPAR4,PLCD4,RASSF8,CFAP126,LRRC75A,IL6ST,INPP5B,KCNN3,ASPRV1,PPM1L,CLDN11,OXTR,PLCL1,GRAMD1C,BDNF-AS,RASGRF2,RET,RGS12,TMLHE,ROBO2,ELP2,KCNIP1,RXRA,NCBP3,FNIP1,FOXRED1,KIF21A,AMBRA1,CPEB4,DBNDD2,RBM26,ADHFE1,NSFL1C,SYNE2,SATB2,TPCN2,SYNE1,SYNPO2,LYPD6,RNF146" MicroRNA hsa-miR-361-5p:PITA hsa-miR-361-5p:PITA_TOP PITA 2.10E-28 1.18E-24 5.88E-28 5.41E-27 58 266 "MTUS1,DPP10,PKP4,ZBTB10,CBFA2T2,ZMYM4,MAGI1,CNOT8,ARMC8,ZNF521,DBT,ZNF804A,MTX3,EBF1,MBNL2,CALCRL,EPB41,RCAN2,GPHN,RRAGB,AFF2,FUT9,PCLO,IGF1,KIF5A,GPR155,MAP2,LRP1B,MXI1,NEXMIF,NFIX,CNTN3,PCDH9,PDE3A,PDE4B,PIK3R1,PKIA,RELN,ZSCAN32,OXR1,SCAF8,PPM1E,CHD9,SEC31A,SOX11,STAU1,PLCB1,RPGRIP1L,ZFPM2,CSMD1,TRPS1,FLRT2,WNT7A,XRCC4,REEP1,FAM13C,ACTR3B,DPF3" MicroRNA hsa-miR-601:mirSVR_highEffct hsa-miR-601:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-28 1.22E-24 6.08E-28 5.60E-27 69 380 "TMEM132B,SYT13,OGT,ANK2,SFMBT2,ARNTL,CARMIL3,RAB29,CBFA2T2,SYNGR3,DGKI,LRBA,FAM19A5,CNTN1,SLC4A8,AHCTF1,CSF1,USP3,ECM2,TENM1,F5,FGF14,TUBGCP4,SRCAP,PPARGC1A,TOX3,GLUL,KDM2B,MIER3,SMAP1,IDH3B,LRRCC1,NME9,KTN1,SYTL4,MYT1,SMIM11A,CCSER2,NLE1,PRKACB,HYDIN,SNRK,ANKHD1,TMEM260,SLC25A36,MCMBP,CSRNP3,SH3BGR,R3HDM2,CNKSR2,NLGN1,ANKRD6,RCOR3,SNRPN,TROVE2,DNAJC9,FAM208A,ADGRL3,SIRT1,METTL3,RUSC1,UGT8,RICTOR,ZBTB38,EML6,ANKS1B,PRDM10,ADAMTS9,FAM198A" MicroRNA hsa-miR-488-3p:TargetScan hsa-miR-488-3p TargetScan 2.22E-28 1.24E-24 6.19E-28 5.70E-27 62 306 "KIAA1211,HECW2,APBB2,MARCH3,RIPK1,CALM1,ARHGEF6,ARHGAP24,KLHL3,CHRDL1,EBF1,RAB9B,FGFR3,FAM49B,FUT9,SDCBP2,GABRB3,RAB30,PRRC2B,PRUNE2,GRIN2D,PTPRT,RNF165,RNFT2,HAS2,IGF1,FAM69A,KCNN3,MAT2A,ADAM11,PPM1L,MMP16,SAMD5,PCSK5,PDE3A,NLGN3,PIK3R1,PCDH18,POLR2F,PKIA,FITM2,APTX,ANKHD1,PRIMA1,CYB561D1,AP1AR,SARS,CCDC88A,FAM126B,HECW1,MYCBP2,PEG10,ANKRD28,ANKRD12,FAM208A,CBX5,CSMD1,PLEKHH2,EML6,PRDM10,RGS7BP,RSPRY1" MicroRNA hsa-miR-1273:mirSVR_lowEffct hsa-miR-1273:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.23E-28 1.25E-24 6.22E-28 5.72E-27 78 483 "AXIN2,PTCHD1,OLMALINC,AP2A2,LTBP4,ARHGDIA,MARK4,TTLL9,HAP1,HIP1R,PRC1,EVI5L,RCBTB2,ASIC3,TPP1,HECTD1,TBPL1,MROH8,PPP1R16B,UBXN2A,KIAA0408,HDAC4,IP6K1,GUCD1,MAMLD1,SEMA3D,COQ7,ANKMY1,ABCA8,GTF2IRD2,FLYWCH1,TMEM107,CAMKK2,ERGIC3,ABLIM2,GGT5,CRCP,COPS8,STARD3,GRIN2C,FAM107A,MUM1,TJAP1,INPP5B,C2CD4C,TTYH2,ZNF862,ZC3H12B,DNHD1,SLC11A2,SMIM11A,CHAMP1,PAX6,GPSM2,PLXNB1,SCHIP1,EPB41L4B,PPM1B,NCR3LG1,MSANTD2,RNASEL,NEK11,ATXN7,MRAS,FNDC3A,TMCC1,FAM126B,SS18,TMEM150C,MTCL1,TBCEL,TPCN2,ARL10,UBTF,LAT2,ATP6V0E2,ANKS1B,LINC02210" MicroRNA hsa-miR-1277:mirSVR_highEffct hsa-miR-1277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-28 1.48E-24 7.38E-28 6.79E-27 75 449 "KIAA1211,PTCHD1,ZNF608,APBA2,NUMB,RNF182,BCHE,NRP2,ST3GAL5,DGKI,LRRFIP1,MAGI1,CDO1,MAP4K4,CNN3,IGDCC3,CLIP3,MROH8,PABPC5,POM121,USP3,ABCC5,E2F6,EBF1,EDIL3,SNX29,TSPAN5,RASGRP1,OPTN,PHF20L1,PLEKHA1,VPS13B,RACK1,FGF12,FHL1,POMT1,SMC2,ST6GALNAC3,CHL1,CRCP,LUZP2,RAB40B,PSIP1,FAM222A,ZHX1,ZNF491,KCND2,HECTD2,MBNL1,MBP,LRP1B,ALDH1L2,NRCAM,PAX6,PCDH9,PFKFB2,CEP41,HYDIN,ANKHD1,PTPRH,PTPRN2,RNASEL,PNMA8A,CCDC102B,SCP2,RCOR3,ZC4H2,NKAIN2,FAM124A,TRPS1,PPIL6,OSBP2,FZD3,KAT6A,RNF170" MicroRNA hsa-miR-30c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-28 1.63E-24 8.12E-28 7.48E-27 81 521 "TAOK1,SEMA6A,MARCH4,PCDH10,ZNF687,USP37,MARK4,STX16,ATP2A2,DPY19L3,ST3GAL5,CFL2,ARHGEF6,TBPL1,BAG4,PREPL,CREM,NCOR2,CSF1,CSNK1E,GAPVD1,HDAC4,MATR3,POM121,SACS,DPYSL2,FEM1B,CELSR3,MRO,ASB3,KCTD3,DCTN4,EPB41,SCML2,DLC1,CHST15,FOXO3,CELF1,MSANTD4,HHIPL1,OGA,IP6K3,RNPS1,DBF4,TNRC6A,MIER3,ELOVL5,LIFR,SMAD1,LYPLAL1,MXI1,PKM,NLE1,PRKAB2,REV3L,NUDT11,PBRM1,SETD5,ALG9,PCMTD2,SBF1,TRA2B,BTBD7,CPEB4,ARFGAP1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,ELOVL4,PLCB1,SLC35G2,NACC2,KLC2,XPO1,MKRN3,ZFAND5,RTN4,PHTF2,ZDHHC20" MicroRNA "ATGCTGC,MIR-107:MSigDB" "ATGCTGC,MIR-107:MSigDB" MSigDB 3.04E-28 1.70E-24 8.45E-28 7.78E-27 51 203 "AXIN2,UNC5A,AK2,OGT,MARCH3,ZBTB10,CHRD,ADGRB1,NRP2,SYNJ1,CACNA2D1,RUNX1T1,ARMC8,PPP6R2,TSPAN5,PHF20L1,EIF5,RASL12,AFF2,NSG1,GABRG2,TMEM121B,CLASRP,ZHX1,BACH2,HLF,AGFG1,KIF5A,MBNL1,LRP1B,ZC3H12B,NF1,NOVA1,PDE4B,PIK3R1,LRRN3,SNRK,RET,RGS4,FBXW7,KIF21A,CPEB3,FAM81A,ZHX3,ADGRL3,SATB2,DICER1,ZFPM2,NR2C2,ZIC1,ADAMTSL3" MicroRNA "ATGCTGC,MIR-103:MSigDB" "ATGCTGC,MIR-103:MSigDB" MSigDB 3.04E-28 1.70E-24 8.45E-28 7.78E-27 51 203 "AXIN2,UNC5A,AK2,OGT,MARCH3,ZBTB10,CHRD,ADGRB1,NRP2,SYNJ1,CACNA2D1,RUNX1T1,ARMC8,PPP6R2,TSPAN5,PHF20L1,EIF5,RASL12,AFF2,NSG1,GABRG2,TMEM121B,CLASRP,ZHX1,BACH2,HLF,AGFG1,KIF5A,MBNL1,LRP1B,ZC3H12B,NF1,NOVA1,PDE4B,PIK3R1,LRRN3,SNRK,RET,RGS4,FBXW7,KIF21A,CPEB3,FAM81A,ZHX3,ADGRL3,SATB2,DICER1,ZFPM2,NR2C2,ZIC1,ADAMTSL3" MicroRNA hsa-miR-501-3p:mirSVR_highEffct hsa-miR-501-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-28 1.72E-24 8.53E-28 7.85E-27 75 450 "ACTN1,KIAA1324,OGT,APAF1,USP37,BCL7A,DST,JAZF1,PTBP2,SLC25A14,ZMYM4,RCHY1,RNF14,DCAF8,DAPK1,NR1D2,DNAJB6,KCTD3,FCGR1A,UBE2E3,AGAP3,ATP13A4,NBEA,ATP6V1H,STAU2,DISC1,MSTN,GLI2,TDRKH,PCLO,GRIA2,CIT,CYP27C1,MBD1,TM6SF1,AFDN,MYCN,NEFM,NF1,CLDN11,PCDH9,PCSK5,PMP22,CCDC144B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,MAPK9,BDNF-AS,ACSM5,ZFHX4,RPL15,ATP8B4,SATB1,SGK1,SEPHS1,EPC1,RCOR3,TRERF1,HECW1,KDM4C,PEG10,ZBTB43,SEPT8,PRRC2C,ITGB3BP,HEY1,UBE2H,KCNT2,EML6,ZNF189,AMN1,GAN,LAS1L" MicroRNA hsa-miR-33a:PITA hsa-miR-33a:PITA_TOP PITA 3.09E-28 1.73E-24 8.60E-28 7.92E-27 54 230 "FMNL2,UNC79,CDC42BPA,DPP10,CAMK2G,USP6,FOXN3,CHN2,MAP4K4,GDA,SEC24C,ZFYVE16,WDR20,RCAN1,CNNM1,OLFM1,AFF2,MSTN,GHR,PPARGC1A,SPIN1,HTATSF1,GPD2,BACH2,MARK1,MEF2C,MEIS2,NFIX,NPY,NOVA1,ENPP2,XRN1,PCDH18,PPP3CA,DIRAS2,FBXW7,SCN8A,CASC3,GALNT10,CPEB3,WDR47,SOX11,ERC1,VPS13A,TCF4,SATB2,RIMBP2,CSMD1,TNS1,TRPS1,KCNE5,TBC1D15,DPYSL5,NAV3" MicroRNA hsa-miR-548c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.33E-28 1.86E-24 9.25E-28 8.52E-27 81 522 "SPOP,TRMT9B,OGT,PARG,TMEFF1,ZBTB10,EIF4G3,BMPR1B,CACNA1A,CALM1,CCNT1,NDST3,CNN3,CPS1,USP6NL,HEPH,MYEF2,GUCD1,MTX3,CPEB2,GOLGA7,DCTN4,CEP85L,DLC1,FOXO3,ST6GALNAC3,MSANTD4,GALC,GPR75,LUZP2,TPPP,ZIC5,METTL21A,KCNB1,KCNN3,LAMP2,PAXBP1,MSANTD3-TMEFF1,MAT2A,MEIS1,MITF,MKLN1,SLC11A2,NUCB2,OLA1,CCSER2,PSAT1,DRAM2,MAPK7,GDPD1,PTCH1,RBBP6,SLC25A36,SETD5,NCBP3,MRAS,TRA2B,SGK1,SH3BP2,CHD9,PEX26,SLC6A8,ATF7IP,TMCC1,SP4,HECW1,NXT2,ELOVL4,DIP2A,FAM208A,TRPS1,ZNF711,ZNF708,ZNF28,LYPD6,DHX33,PRDM10,TRIM16L,FXR1,GAN,SPATA13" MicroRNA hsa-miR-600:PITA hsa-miR-600:PITA_TOP PITA 3.34E-28 1.87E-24 9.27E-28 8.53E-27 56 249 "KLHL13,ALCAM,MAP4K3,APBB2,SYNJ1,PTBP2,CCK,DLGAP2,CCPG1,EPS15L1,SLITRK5,ZNF804A,MYEF2,KCTD3,DLC1,AFF2,NBEA,C15orf41,ARFIP1,SPIN1,FERMT2,TOX2,NEGR1,KCND2,STMN1,MAT2A,MSI1,MYO5A,RTL5,ZC3H12B,NOVA1,PCDH8,RETREG1,PPARA,PPP3CA,DIRAS2,PTPRD,ROBO2,TNFRSF19,ITPRID2,ST5,SYPL1,TCF4,TCF12,SZT2,TNS1,NR2C2,SGK3,UBE3A,UBTF,UCHL1,EMSY,STOX2,KAT6A,PHTF2,ST8SIA2" MicroRNA hsa-miR-524-3p:mirSVR_lowEffct hsa-miR-524-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-28 1.91E-24 9.48E-28 8.73E-27 71 405 "DGCR6,EMILIN3,ESYT2,PDZD4,PITPNM2,AMPD2,SEMA7A,CDC14B,NAE1,VXN,SCARB1,IGLON5,PPP1R16B,ERC2,ZNF337,TBC1D5,LIN54,AIF1L,ARMCX4,PITPNC1,WDR20,SLC29A4,HIPK3,SUCO,SEMA4D,PDLIM5,FAM49B,ZNF274,GRB10,ZBTB49,ADAMTS6,KIF5A,PAXBP1,MN1,BLOC1S2,MXI1,HNRNPM,CDK18,FAM216A,PLCB2,PLIN1,SDK2,PPP1R1A,MAPK4,ZIK1,C1orf109,SLC25A48,CCDC82,KLHDC8A,ROBO1,TCP11L1,RYR3,ARX,SEPHS1,SLC11A1,INAVA,KDM4B,ZSWIM8,SPART,SSTR1,SS18,MPRIP,MLST8,SATB2,ZFPM2,TPM2,TRO,WIPF1,EML6,HNRNPA3,CPNE4" MicroRNA hsa-miR-4256:mirSVR_highEffct hsa-miR-4256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.54E-28 1.98E-24 9.82E-28 9.04E-27 83 547 "ACADM,AS3MT,PWWP2A,CEP126,OGT,MAP4K3,CDK10,ARNTL,STX16,MYOM1,BACH1,PTBP2,NOG,CFL2,ABCG2,QKI,ARMC8,COX4I1,LRIG1,ARHGEF10,PDE4DIP,GREB1,ARHGAP24,GIT2,TIAM2,ZC3H11A,SV2B,WDR20,CHRDL1,DMTF1,FSD1L,F8,ZNF461,RGPD5,SMC2,APOPT1,STAU2,ACSS1,LNX1,FUT10,GPR37,PRDM5,HSF2,FAM95B1,MMP16,NELL2,NTRK2,ZNF713,P2RX7,FSD1,TATDN3,MASP1,PTPRG,PTPRO,PID1,SUSD4,MORC4,ZFHX4,CCDC82,CARF,RORB,RPE,KIAA0895L,ATP8B4,MRAS,WDR47,ZKSCAN3,SP4,ATP10B,SS18,ZSCAN29,MCF2L,SYNE1,FRYL,TIAM1,MTMR14,ERCC6L2,WIPF1,MICU3,ZNF189,TFIP11,EPM2A,IFT88" MicroRNA hsa-miR-139-5p:PITA hsa-miR-139-5p:PITA_TOP PITA 3.69E-28 2.07E-24 1.03E-27 9.43E-27 63 319 "NDRG2,TAOK1,LRCH2,ZBTB10,ATP2B2,SCAPER,MTMR2,CACNA2D2,SOCS5,USP6NL,KIAA0408,SPOCK3,DMD,DPP6,TSPAN5,MBNL2,EIF4G2,EMX2,OLFM1,MEX3B,FOXO3,GATM,PPARGC1A,TNRC6A,LPAR4,GPR37,ELOVL5,MAP2,MARK1,MAT2A,MBD1,MBNL1,MEIS2,NPTX1,NRCAM,PDE3A,PDE4D,PMP22,LRP12,SCHIP1,PBRM1,ZNF532,LRFN5,BTBD3,WDR47,CPEB4,SMARCA4,TMCC1,CDK19,ERBIN,SEPT3,NECAB1,TCF4,TCF12,FRYL,CLDND1,ZIC1,TRIM9,NDRG4,ZBTB38,FZD3,RTN4,KAT6A" MicroRNA hsa-miR-10a-5p:Functional MTI Functional MTI miRTarbase 3.72E-28 2.08E-24 1.03E-27 9.48E-27 76 463 "SLC24A4,INTS2,AMPD2,LRFN1,C6orf89,ZBTB10,SYNJ1,C5,ZNF445,ABCG2,CCDC151,C2CD2,CRY2,NCOR2,IPCEF1,USP6NL,CENPL,TMEM170A,MYEF2,MTX3,MED12,NR1D2,DPYSL2,FEM1B,EIF1,EPB41L2,ADGRV1,FGFR1,SPECC1,CHL1,SEPT9,MSL3,GNAL,LILRA2,PTPRT,SYNPO,IL12A,KLHL23,LSS,MBD1,NPTX1,SLC11A2,OCRL,PDPK1,XRN1,RELN,CNTLN,ELOVL2,PTPRG,KLHDC8A,RPL15,NCBP3,CSRNP3,TRA2B,ZFP30,KIF21A,CDK19,KANK1,PRRC2C,C12orf76,FAM208A,TRIM2,PUM2,TIAM1,NACC2,NR2C2,RUNDC3B,UBTF,BCL2L13,CFAP298,ZNF708,LYPD6,ZFAND5,TUBA1A,FAM219B,TTC7A" MicroRNA hsa-miR-33b:PITA hsa-miR-33b:PITA_TOP PITA 3.90E-28 2.18E-24 1.08E-27 9.94E-27 54 231 "FMNL2,UNC79,CDC42BPA,DPP10,CAMK2G,USP6,FOXN3,CHN2,MAP4K4,GDA,SEC24C,ZFYVE16,WDR20,RCAN1,CNNM1,OLFM1,AFF2,MSTN,GHR,PPARGC1A,SPIN1,HTATSF1,GPD2,BACH2,MARK1,MEF2C,MEIS2,NFIX,NPY,NOVA1,ENPP2,XRN1,PCDH18,PPP3CA,DIRAS2,FBXW7,SCN8A,CASC3,GALNT10,CPEB3,WDR47,SOX11,ERC1,VPS13A,TCF4,SATB2,RIMBP2,CSMD1,TNS1,TRPS1,KCNE5,TBC1D15,DPYSL5,NAV3" MicroRNA hsa-miR-542-5p:mirSVR_lowEffct hsa-miR-542-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.29E-28 2.40E-24 1.19E-27 1.09E-26 76 464 "ACHE,CLK4,ALCAM,LRFN1,DPP10,SUGT1P4-STRA6LP-CCDC180,APAF1,LGR5,CDK10,LINC00173,TMEM108,N4BP2L1,TTLL9,SLC25A14,CBLN1,LY86,SLC4A8,GAL3ST1,MATR3,MAML1,SNAP91,RASA4,KCTD3,EZH1,STRADA,FGF14,SEMA4D,EFCAB2,AKAP3,GABRB3,TRAF3IP2,DISC1,TCERG1,CBX1,ADGRA3,FAM19A2,RNF165,IL6R,ITGAM,MID1,MYO7A,BEX5,SFR1,PDE4B,SLC25A23,CNTLN,MTMR10,PTPRE,CCDC40,RDX,RGS12,CLIP1,CASC3,FBXO11,FAM81A,SLC22A4,SMARCD3,ANKRD36,DIP2A,ANKRD28,OBSL1,TNS2,FAM200B,ICAM5,LRRC8A,DCBLD1,LINC00689,VIPR2,ZNF70,ZNF74,SH3GLB2,EMSY,PRDM8,DNAH10,UBE3B,NHSL1" MicroRNA hsa-miR-324-5p:mirSVR_highEffct hsa-miR-324-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.69E-28 2.63E-24 1.30E-27 1.20E-26 66 352 "ACADM,SYS1,ADD2,PCDH19,CDC42BPA,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PKP4,FUBP1,DGKI,FAM189A2,FHL5,CNTN1,PCYT1B,RTTN,TOGARAM2,CNRIP1,HINFP,SIPA1L1,USP6NL,DOCK4,DBI,DMD,DNAH9,PDCD6IP,RCAN1,OPTN,TMEM35A,CEP78,FGF11,DISC1,GRIA2,FAM19A2,ARHGAP36,IDH3A,ZIC5,KCND2,MAT2A,MGAT3,MYO7A,CCSER2,PPP2R5E,APTX,CNTLN,PTPRD,PTPRE,RNASEL,ZNF532,SETD5,EXD2,SATB1,FBXO11,NAPB,RCOR3,TMCC1,SEPT8,SULF2,SEPT3,SLC19A3,ARL10,R3HDM1,GUSBP1,ZNF189,HPS4,RNF170,GAN" MicroRNA hsa-miR-3158:mirSVR_highEffct hsa-miR-3158:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.70E-28 2.63E-24 1.30E-27 1.20E-26 92 664 "SYS1,RNF150,DPY19L2P4,HECW2,HFM1,AQP6,MARCH3,N4BP2L1,ADAM23,SRSF11,PPT2,ENTPD4,CLIP3,APPL1,RIMS2,GPRASP1,ZBTB24,USP3,DNM1L,WDPCP,FRY,KMT5B,SMC2,USP21,CELF1,IQGAP2,CYP46A1,GHR,BRD8,TOX3,LNX1,GPD2,TDRKH,GRIA2,PLPP7,GRM8,BVES,HLF,HNMT,ZIC5,STXBP5,KTN1,L1CAM,MBD1,AFDN,NCF2,SLC11A2,PAX6,PDE4D,ENPP2,KCTD15,PMP22,SEPT4,EPB41L4B,PKIA,RELN,VPS13C,PTPRE,NWD1,ZNF493,MSANTD2,COPZ1,ARX,FBXO11,FAM214B,SLC6A11,SLC14A1,CPEB4,KIF13A,NFASC,POGZ,ZSCAN29,SEPT8,TMEM150C,MTCL1,MCF2L,ZFP90,NAT16,PCDHB4,SIK3,TK2,PCDH20,ZXDA,EMSY,MFF,DNALI1,RNF103,PDSS2,EPM2A,RTN4,IFT88,CPNE4" MicroRNA hsa-miR-520a-5p:PITA hsa-miR-520a-5p:PITA_TOP PITA 5.15E-28 2.88E-24 1.43E-27 1.31E-26 56 251 "FZD9,CAMK2A,CAMK2G,SEPT7,DLGAP2,FOXN3,CLTB,RCHY1,SEC24C,CNTNAP2,ERC2,DCAF8,TMCC2,DMD,KMT5B,ELN,AGAP3,ATP6V1H,IQGAP2,GFRA2,CDH20,SMAD1,MAP2,MEIS1,MEIS2,MID1,NDP,NFIX,NOVA1,SLC11A2,PDE1B,NLGN3,PIK3R1,ANKRD16,PPP2R5E,PSD,TMEM260,UBR7,RGS4,SETD5,RTN1,SEMA6D,ATXN7,ZNF821,SGK1,PPP4R3A,SLC8A1,FNBP1,FBXW11,SATB2,RPGRIP1L,NSD1,PUM2,THRA,CADM2,PPP1R3F" MicroRNA hsa-miR-525-5p:PITA hsa-miR-525-5p:PITA_TOP PITA 5.15E-28 2.88E-24 1.43E-27 1.31E-26 56 251 "FZD9,CAMK2A,CAMK2G,SEPT7,DLGAP2,FOXN3,CLTB,RCHY1,SEC24C,CNTNAP2,ERC2,DCAF8,TMCC2,DMD,KMT5B,ELN,AGAP3,ATP6V1H,IQGAP2,GFRA2,CDH20,SMAD1,MAP2,MEIS1,MEIS2,MID1,NDP,NFIX,NOVA1,SLC11A2,PDE1B,NLGN3,PIK3R1,ANKRD16,PPP2R5E,PSD,TMEM260,UBR7,RGS4,SETD5,RTN1,SEMA6D,ATXN7,ZNF821,SGK1,PPP4R3A,SLC8A1,FNBP1,FBXW11,SATB2,RPGRIP1L,NSD1,PUM2,THRA,CADM2,PPP1R3F" MicroRNA hsa-miR-4258:mirSVR_lowEffct hsa-miR-4258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-28 2.96E-24 1.46E-27 1.34E-26 65 342 "SYS1,ADD2,FAM135A,PCDHGB4,EIF4G3,BCL7A,ZNF599,NUMBL,PPT2,SLC4A8,CSNK1E,PDE4DIP,GREB1,RUBCN,KATNAL2,SCRN1,DUSP9,DNAJB6,TNK2,ELN,TMEM132C,APOPT1,CGREF1,SIGLEC8,GFER,TNRC6A,ZNF638,HMGCL,ZNF678,INSM1,MAT2A,MX1,NNAT,PCDHGC3,PLCL1,BCAS3,ACSS3,PRRT2,CARF,SLC6A8,ARFGAP1,ANKRD36,FNBP1,ZSWIM8,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,SIK3,VIPR2,NDRG4,CRB2,PCBP4,PARP11,DOCK8,TMEM63C,FRMD6" MicroRNA hsa-miR-569:PITA hsa-miR-569:PITA_TOP PITA 5.71E-28 3.19E-24 1.58E-27 1.45E-26 55 242 "SEMA6A,APAF1,STX16,KSR1,FUBP1,CALM1,RUNX1T1,CCPG1,CLCN3,MAP4K4,NSL1,SH2B1,PNPLA8,DOCK4,LONRF1,E2F5,PAN3,ENPP6,EYA1,AFF2,CHL1,GABRG1,MSTN,PCDH17,GNG4,ATXN2L,AGFG1,MAP4,KITLG,NOVA1,PDE4D,POLG,TMEM255A,OXR1,RFX3,RIC8B,SALL1,FNDC3A,SEPHS1,TET1,SMARCA4,PDZD2,ERC1,NFASC,CLASP2,TRIM2,AP4E1,SGK3,TBC1D15,XPO1,ZBTB38,SMARCAD1,SLC38A1,PDSS2,KAT6A" MicroRNA hsa-miR-3177:mirSVR_lowEffct hsa-miR-3177:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.88E-28 3.29E-24 1.62E-27 1.50E-26 79 502 "ABR,ADD2,MTA3,AP2A2,LRFN1,DOCK11,RGS11,GYG2,DLGAP1,ARMC8,HINFP,DBI,KIAA0319,SNAP91,TMCC2,CDON,IRAK4,SLC43A2,NCALD,ANKMY1,EYA1,FGF11,BAIAP2,SEPT9,STARD3,POLL,DCLK2,GPT2,LINC01089,FAM107A,UBE2QL1,GATD1,STMN1,NCOA7,SMAD9,SCAMP5,AFDN,N6AMT1,ZC3H12B,NTRK3,PALM,PLCB2,MAPKAP1,MAPK4,EPDR1,PIGG,PTPRB,PTPRE,RIPOR1,ZFHX4,TCP11L1,ABCA11P,SCP2,CCDC92,ATF7IP,GKAP1,FAM219A,SP2,TEX2,TROVE2,SSTR1,SSPO,CEP68,STXBP1,SYN2,KIAA1107,NEU4,RPGRIP1L,CYB561A3,GPR161,THRA,TNS1,BCL2L13,PLPPR2,VLDLR,LMF1,UPF3A,DPF3,LAS1L" MicroRNA hsa-miR-644:mirSVR_highEffct hsa-miR-644:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.91E-28 3.31E-24 1.63E-27 1.50E-26 85 576 "CARNS1,PKP4,FAM131A,MARCH3,DYNLL1,BCS1L,DST,CAMK2B,CLDN10,CHGB,NRXN3,MYRIP,ZFP28,CNRIP1,SEC31B,ABCG1,UBXN2A,CTH,DCAF4,HDAC9,KIAA0586,DMTF1,DNM1L,PHF20L1,SUGP2,EPB41L2,EPHB1,RACK1,KAT8,FGF1,FOXF2,SYNCRIP,FLNC,RASL10A,TUBGCP4,SRCAP,LUZP2,ZNF782,PRUNE2,HMGCL,CFAP126,C2orf72,IPO5,PAXBP1,MAN2A2,MAT2A,MBD1,NEFH,NF1,DNHD1,NUCB2,GLIPR1L2,PDE1C,PDE4D,GNG2,ZDHHC8,MINDY2,PPM1B,MAPK9,DIRAS2,PTPRO,RET,SLC25A36,NUDT11,PBRM1,EXD2,KIRREL1,ROBO2,KCNIP1,FERMT1,SHMT2,CCDC92,ZNF430,BTBD7,NFASC,ASTN2,TCF4,TRIM2,ERCC6L2,TPM1,TSN,ZNF154,SEMA3B,RTN4,PHTF2" MicroRNA hsa-miR-365*:mirSVR_highEffct hsa-miR-365*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.35E-28 3.55E-24 1.75E-27 1.61E-26 75 455 "UNC79,VAT1L,ARNTL,PDE8B,SYNJ1,CACNA1B,THSD7A,CDO1,PLEKHB1,EPS15L1,PPT2,IQCK,SOCS5,RIMS2,HDAC9,DCAF8,ZFYVE16,PLPPR4,ECM2,GOLT1B,EBF1,PHC2,EIF1,CEP85L,ABCA8,FAM198B,TAOK3,IP6K2,ANKFY1,CAMKK2,ATP2C1,ZNF559,PCLO,RNF165,MYLK2,LAMP2,LIMS1,MBNL1,BLOC1S2,RTL5,OPA1,CNTN3,TMIE,PPP2R5E,HYDIN,ANKHD1,PTPRE,RET,UBR7,RGS3,EXD2,HSD11B1L,RYR3,R3HDM2,DHX30,SEPHS1,RCOR3,SNRPN,IZUMO4,SPART,ATP10B,CLSTN2,POGZ,SLC37A2,DNMBP,ZFP90,WIPF1,P2RY12,ZNF24,ZNF142,MAP3K12,PRTFDC1,STOX2,PHTF2,FAM198A" MicroRNA "TAGCTTT,MIR-9:MSigDB" "TAGCTTT,MIR-9:MSigDB" MSigDB 8.15E-28 4.56E-24 2.25E-27 2.07E-26 53 225 "PCDH19,OSBPL8,PITPNM2,EPB41L5,CASK,ARNTL,STX16,JAZF1,CAMK2G,KRIT1,ZMYM4,MAGI1,CFL2,QKI,KLHL3,CPEB2,YAF2,PHF20L1,GPHN,MSANTD4,GABRB3,CIT,SOX21,ZHX1,BACH2,NEGR1,AGFG1,INSM1,LRRTM1,KCNN2,MEF2C,MITF,MMP16,CCSER2,PCDH18,STRN3,LRP12,CEP41,ZFHX4,CPEB3,CPEB4,LMBRD1,SOX3,ERBIN,VPS13A,ATMIN,TCEA1,ZFPM2,TPM1,EIF4ENIF1,ZIC2,FXR1,SOCS4" MicroRNA hsa-miR-556-3p:PITA hsa-miR-556-3p:PITA_TOP PITA 9.30E-28 5.20E-24 2.56E-27 2.36E-26 49 190 "FMNL2,CCDC85A,ADRB2,PCDH19,KCTD16,OGT,LRCH2,SLC4A4,STX16,RCBTB2,PLCXD3,HDAC4,ZFYVE16,MATR3,DNAJB6,MBNL2,ERBB4,ACSL4,VTI1B,PPARGC1A,FAM19A2,HLF,HNF4G,AGFG1,IGF1,MEF2C,MEIS2,NFYA,PKIA,PID1,ZFHX4,SEMA6D,SEC14L1,SCAF8,CPEB3,SLC12A2,HECW1,STAU1,SEPT8,ADGRL3,FBXW11,TRIM2,AP4E1,NR2C2,TRPS1,KCNE5,CLDND1,ZFAND5,RGS7BP" MicroRNA hsa-miR-190:PITA hsa-miR-190:PITA_TOP PITA 9.58E-28 5.36E-24 2.64E-27 2.43E-26 45 157 "ZNF608,KLHL13,TBC1D14,OSBPL6,ADGRB3,SYNJ1,LDLRAD4,SOCS6,NRXN3,CNN3,SEC24C,BOC,MYEF2,DMD,DRP2,SEMA3D,TENM1,GPHN,TAOK3,MEX3B,NBEA,MEGF10,C15orf41,TNRC6A,HAS2,BACH2,NEGR1,MEF2C,PCDH9,XRN1,PPP2R2C,DIRAS2,ROBO2,SGSM1,TRA2B,FNDC3A,NLGN1,MYCBP2,LARP4,KLHL7,TCF4,DICER1,CSMD1,CELF4,NAV3" MicroRNA hsa-miR-190b:PITA hsa-miR-190b:PITA_TOP PITA 9.58E-28 5.36E-24 2.64E-27 2.43E-26 45 157 "ZNF608,KLHL13,TBC1D14,OSBPL6,ADGRB3,SYNJ1,LDLRAD4,SOCS6,NRXN3,CNN3,SEC24C,BOC,MYEF2,DMD,DRP2,SEMA3D,TENM1,GPHN,TAOK3,MEX3B,NBEA,MEGF10,C15orf41,TNRC6A,HAS2,BACH2,NEGR1,MEF2C,PCDH9,XRN1,PPP2R2C,DIRAS2,ROBO2,SGSM1,TRA2B,FNDC3A,NLGN1,MYCBP2,LARP4,KLHL7,TCF4,DICER1,CSMD1,CELF4,NAV3" MicroRNA hsa-miR-574-3p:mirSVR_lowEffct hsa-miR-574-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-27 5.92E-24 2.91E-27 2.68E-26 65 346 "AP2A1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,MADD,SLC2A11,DPY19L3,MPDZ,BMPR1B,SYNJ2,CAMK2G,TIGD7,TAOK2,COL9A1,SMARCAL1,VCAN,ERC2,ARHGEF4,DNM1,DPP6,DPYSL2,FRY,EGFR,RCAN2,SPEG,FHL1,POLK,SUCO,MEX3B,FOXF2,PRELID3A,ARFIP1,GFRA2,CSDC2,SPIN1,GPD2,SOX21,MAP2,KITLG,MMP16,LAYN,PIK3R1,PMP22,MINDY2,PRKAR1B,PRKCB,WBP1L,RASGRF1,DCUN1D2,CCDC25,SBF1,SNRPN,ADAMTS17,TCF4,ZEB1,TPCN2,SYNE1,NAT16,CDK20,CLHC1,TUBB1,SPIRE1,PCBP4,UBE3B,SMIM8,DPF3" MicroRNA hsa-miR-487a:PITA hsa-miR-487a:PITA_TOP PITA 1.10E-27 6.18E-24 3.03E-27 2.79E-26 55 245 "HECW2,ARHGAP20,PPP4R4,CALB2,LDB2,ZMYM4,SRSF11,FOXN3,TMEM184B,CNR1,CLOCK,GDA,DOCK4,GAPVD1,DAPK1,YTHDC1,ZC3H11A,SGSM2,PDCD6IP,HIPK3,FAM13A,ETV1,CHL1,CPLX2,MMADHC,PPARGC1A,ZNF638,SMAP1,ZIC5,AFDN,PDE4D,PIK3C2A,PDZRN4,MAPKAP1,EPB41L4B,PPP2R5E,KANSL1,PTCH1,MTMR10,RFX3,CARF,TMCC1,PDZD2,ARHGAP26,SPART,PLCB1,SYN2,RPGRIP1L,PUM2,SIRT1,KCNE5,ZNF711,EVI5,FAM13C,SMIM8" MicroRNA "GCAAAAA,MIR-129:MSigDB" "GCAAAAA,MIR-129:MSigDB" MSigDB 1.19E-27 6.63E-24 3.26E-27 3.00E-26 47 174 "ACTN1,XKR4,ZNF608,PHF12,APC,ZBTB10,EIF4G3,RUNX1T1,USP6,DLGAP2,NRG2,ZNF385A,MATR3,ABCC5,YAF2,EPHB1,ETV1,ACSL4,TAOK3,PDLIM5,GFRA2,GLYR1,RNF165,BACH2,MEIS1,MEIS2,PAX6,PIK3R1,PDZRN4,ING3,SH3KBP1,PRKCB,OXR1,FIGN,FBXW7,SCN8A,SEC14L1,SP4,NKAIN2,SYT1,CAMTA1,ADGRL3,NR2C2,TRIO,TBC1D15,CELF4,STOX2" MicroRNA hsa-miR-4722-5p:Functional MTI Functional MTI miRTarbase 1.28E-27 7.18E-24 3.52E-27 3.24E-26 86 595 "AS3MT,NDRG3,ADD2,SLC24A4,CASKIN1,TXNDC16,AMH,PHF12,APAF1,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,DDR1,ZNF555,PTBP2,CBS,SLC16A4,CFL2,NRXN3,SLC35F1,CS,IPCEF1,PITPNM3,UBXN2A,RUBCN,MYADM,TMEM170A,ELMSAN1,SLC29A4,SNX29,HEYL,MRNIP,APC2,VPS26C,ZNF585B,ATP13A4,MSANTD4,AHDC1,CRCP,GPR75,GLUL,ZNF638,BVES,RABL2A,ATOH8,PACSIN2,AGBL5,SHISA6,KCNH2,KLHL23,KIF5A,SMAD9,MEIS1,PPM1L,MXI1,NFIX,CDK18,PKM,MTRF1L,MTMR10,ZNF844,QDPR,MSANTD2,ALG9,GSTCD,SNX22,PTGR2,HSD11B1L,NCBP3,SEMA6D,SLC2A5,MYH15,IQSEC2,CDK19,FAM208A,MGRN1,SLC19A3,PCDHA6,HIF3A,SSBP2,RPRM,USP1,GDPD5,MPPE1" MicroRNA hsa-miR-425:PITA hsa-miR-425:PITA_TOP PITA 1.30E-27 7.28E-24 3.57E-27 3.29E-26 50 200 "ZNF608,KLHL13,AMPH,CFL2,SRSF11,FOXN3,ARMC8,WHRN,AKAP5,MYRIP,SEC24C,MAML1,DGKG,ELMSAN1,CPEB2,GOLT1B,DNAJC27,AFF2,CPLX2,PCLO,HLF,ELOVL5,IGF1,ITPKB,KCND1,IPO5,STMN1,LRP1B,MEF2C,GIT1,MYO5A,CNOT4,OCRL,MINDY2,PTCH1,PTPRN2,FIGN,CHD9,PPP4R3A,EPN2,SNAP25,PDZRN3,TEX2,ZNF423,PRRC2C,SYN2,RPGRIP1L,DICER1,TMEM237,KAT6A" MicroRNA hsa-miR-1913:mirSVR_highEffct hsa-miR-1913:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-27 8.38E-24 4.11E-27 3.78E-26 75 461 "GALNT16,CDC42BPA,PI16,UPRT,PPP4R4,ARRB1,STK33,DNAH17,DPY19L3,ARHGEF7,LRBA,LRRFIP1,COX4I1,CRMP1,ABCG1,SEC24C,ZSCAN23,DCAF8,IP6K1,YTHDC1,DPP6,EDN3,FCF1,FRY,PHF20L1,EPHB1,ZSCAN30,FDFT1,IP6K2,EFCAB2,WDR83,TRIM16,CGREF1,OGA,GABBR1,NEU3,DCLK2,PLCD4,AP4S1,RNFT2,SOWAHA,KIF5A,L1CAM,MXI1,LYRM9,SETD4,PIK3R1,PNMA3,PPP5C,CNTLN,MTMR10,STK32A,ZCWPW1,RGS4,ZNF532,TMLHE,SCN8A,COPZ1,HKDC1,CNKSR2,FAM214B,SLC9A5,HECW1,DBNDD2,TSPYL2,SS18,TBCEL,THRA,ELP5,ZBTB14,ZNF711,INTS3,DNALI1,WNK2,HNRNPA3" MicroRNA hsa-miR-3064-5p:TargetScan hsa-miR-3064-5p TargetScan 1.60E-27 8.94E-24 4.39E-27 4.04E-26 71 415 "NDRG3,OGT,C6orf89,KIF1A,FUBP1,CAMK2G,CCNT1,HECTD1,BAG4,CLOCK,C2CD2,CRY2,CSF1,CNTNAP2,DGKG,IP6K1,JAKMIP2,KLHL3,FAM107B,RPS6KL1,DPYSL2,FARSB,CELSR3,EIF5,RABEPK,AGAP2,PSD2,CELF1,GABBR1,B4GALNT1,MTHFD2,INPP5K,CPLX2,GFRA2,PTPRT,RASSF8,NXPH3,KIAA1755,IL6R,KCNB1,KCNN3,KIF2A,GIT1,SAMD14,NFIX,NFYA,NNAT,NOVA2,PCSK5,PDE1B,KCTD15,PLEC,CNNM2,CYB561D1,RORB,DZIP1,ABLIM3,EPC1,FAIM2,CLSTN2,PHLDB1,RPGRIP1L,NACC2,CBX5,FAM124A,ELP5,BCL2L13,PCDH20,INTS3,DNALI1,MSRB3" MicroRNA hsa-miR-515-5p:PITA hsa-miR-515-5p:PITA_TOP PITA 1.72E-27 9.60E-24 4.71E-27 4.33E-26 62 317 "FAM131A,USP37,ZFYVE28,CHRD,NCOA1,SLC4A4,ATP1B3,DPY19L3,NRP2,CACNA1A,CACNB4,CALM1,QKI,MAP4K4,ZNF385A,PUM1,TM9SF4,MATR3,ALKBH8,POM121,SNAP91,DMD,CPEB2,PAN3,EMX2,RASGRP2,ETV1,CLVS1,TAOK3,TMEM164,SYNCRIP,TMEM107,MEGF11,MSTN,ADAMTS6,HNF4G,INSM1,KCND2,KIF2A,MSI1,MXI1,MINDY2,PTPRD,PTPRE,PEX2,RIPOR1,SLC25A36,SETD5,SCN8A,CASC3,EPN2,PKNOX2,SNAP25,SP4,NMNAT2,PLCB1,TCF12,TIAM1,RGMB,UBE2H,POLR3H,RGS7BP" MicroRNA hsa-miR-1180:mirSVR_lowEffct hsa-miR-1180:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-27 1.10E-23 5.38E-27 4.95E-26 79 511 "XKR4,ADD2,BRAP,AK2,LTBP4,ATP1A1,CAPN3,PLEKHB1,NRXN3,PPT2,IGDCC3,GDA,CSF1,RGS6,CSF2RA,DOCK4,DDX46,DMD,DPH1,EGFR,ELN,EIF1,ENO2,EPHB1,SRRM1,ZNF589,POLK,WDR83,APOPT1,RAPGEF6,SESN1,GFER,STON1,STMN2,GABARAPL2,AGBL5,HP,KCNH2,MBD1,GIT1,NF1,NINJ2,OGG1,P2RX7,PFKFB3,SEMA5B,TMIE,CEP41,MAPK10,ELOVL2,DGLUCY,SALL1,SCP2,PPM1E,MBD5,HECW1,ZNF423,MCF2L2,ZSCAN29,CAMTA1,EXOC7,KIAA1107,SMG6,RNF216P1,PMS2CL,AKTIP,ENHO,ASXL3,ANKRD24,ELP5,ZBTB38,POLR3H,FTSJ1,ZNF213,MFF,DNALI1,SEMA3B,URM1,ADAMTS10" MicroRNA hsa-miR-491-3p:PITA hsa-miR-491-3p:PITA_TOP PITA 1.99E-27 1.11E-23 5.44E-27 5.00E-26 59 287 "CCDC85A,PTCHD1,HECW2,SEMA6A,ALCAM,C6orf89,NCOA1,JAZF1,CABP7,CBFA2T2,LRBA,ZMYM4,FOXN3,RAB33A,AKAP5,DOCK4,DGKB,SPOCK2,SNAP91,DMD,DYNC1I1,NR1D2,CPEB2,PDCD6IP,GOLT1B,EIF4G2,FGF13,FOXO3,GABRB3,FAM19A2,MAP4K5,AGFG1,NKD1,MARK1,MBNL1,CHIC1,MEF2C,ZC3H12B,NOVA1,PDE4D,KANSL1,FAM184A,FIGN,ZFHX4,CLIP1,RTN1,FNDC3A,CPEB4,CDK19,LARP4,PRRC2C,PLCB1,SYN2,MTCL1,PUM2,TEK,DICER1,SIRT1,SLC44A1" MicroRNA hsa-miR-7977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-27 1.16E-23 5.67E-27 5.22E-26 91 664 "NCKAP5,PLEKHH1,SLC24A4,HECW2,TXNDC16,ZNF578,TRMT9B,SEMA7A,APAF1,CPNE5,AQP6,ZNF582,SYNJ2,ISPD,CBS,SLC16A4,CBFA2T2,LONRF2,NDST3,AKAP5,PPP1R16B,APPL1,GREB1,ZSCAN23,MYADM,DNAL1,ELMSAN1,MRO,PLEKHA1,IGSF6,ZNF585B,SCML2,ZNF589,FGFR1,ANKFY1,NSG1,TRAF3IP2,MTHFD2,GNG4,BVES,RNFT2,IRAK3,NEGR1,ZNF546,IGF1,IBA57,METTL21A,KCNJ5,KLHL23,KIF5A,MATN3,PPM1L,SAMD5,ZC3H12B,ZNF426,STRN3,APTX,CEP97,ZMAT4,PRRT2,C12orf49,ALG9,ELP2,NCBP3,CSRNP3,ZFP30,SH3BP2,R3HDM2,SLC2A5,SEPHS1,ZKSCAN3,INAVA,FAIM2,UHRF1BP1L,MCF2L2,SS18,MPRIP,ZSCAN29,CYB561A3,MTMR14,CBX5,ERCC6L2,TUBB2A,RPL7L1,ZNF708,ZNF17,ZNF154,EVI5,FBXO36,ZDHHC20,GAN" MicroRNA "CTATGCA,MIR-153:MSigDB" "CTATGCA,MIR-153:MSigDB" MSigDB 2.14E-27 1.20E-23 5.87E-27 5.40E-26 50 202 "XKR4,OSBPL6,APC,SEMA4G,CDK13,SLC4A4,CAMK2G,MAGI1,DLGAP2,CLTC,QKI,CNN3,AKAP6,CREM,MFAP3L,KLHL3,DLX1,DMD,SCML2,CAMKK2,DOT1L,PPARGC1A,RNF165,KCND1,MAT2A,KCTD6,TAGLN3,NFE2L2,PIK3R1,CCSER2,LRP12,PPP3CA,KANSL1,MAPK4,ROBO2,RYR3,BTBD7,EPC1,SNAP25,SNCA,SOX11,PLCB1,SYT1,CUX2,ZFPM2,SGK3,FLRT2,SPHK2,DPYSL5,SLC30A3" MicroRNA hsa-miR-135b*:mirSVR_highEffct hsa-miR-135b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-27 1.38E-23 6.74E-27 6.21E-26 73 441 "KCNH8,ADD2,CC2D2A,ALCAM,ANK2,KCNAB2,CDK10,PPP4R4,CA12,CAMK2B,USP2,ABCG2,CNRIP1,NCOR1,MYEF2,FBXL5,PLPPR4,RAB39B,CPEB2,DPYSL2,FCF1,RASGRP1,EMX2,EPHB1,IGSF6,DNAJC27,SIRPB1,SUCO,GLYR1,MAP7D2,WDFY3-AS2,STMN2,COQ10A,SMAP1,MSL1,ZNF546,KCND1,LIMS1,SMAD9,ZNF680,P2RY13,NPTX2,PFKFB4,PURG,C19orf57,BDNF-AS,MARCH1,ZNF493,PBRM1,CCDC82,ROBO1,CSRNP3,LRFN5,COPZ1,KIF16B,CCDC88A,SMARCD3,PDZRN3,NMNAT2,NEK4,KANK1,CAMTA1,TEK,ITGB3BP,ZNF610,PLEKHH2,ZNF708,ZNF28,ZNF138,PARP11,HNRNPA3,CASC15,ADAMTS10" MicroRNA hsa-miR-15b-5p:Functional MTI Functional MTI miRTarbase 2.51E-27 1.40E-23 6.85E-27 6.30E-26 98 760 "AXIN2,FZD9,USP31,CASKIN1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,CASK,ARHGDIA,ZBTB10,ATP2A2,DOCK11,BCL7A,SYNJ1,MTMR3,CA8,RUNX1T1,CCNT1,ENTPD6,TBRG4,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,DMPK,USP3,CPEB2,DMTF1,FCF1,HEYL,PLEKHA1,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,MSANTD4,RNPS1,RAB40B,GNAL,AP4S1,NEGR1,MSL1,RBPJ,LAMP2,CHIC1,SCAMP5,AFDN,MYO5A,HNRNPM,OCRL,ETFRF1,PDE4D,PIK3R1,PSAT1,QRICH1,PTPRD,RBBP6,ZFHX4,RNH1,SALL1,HSPA4L,CPEB3,DHX30,ANKRD36,MYCBP2,KANK1,STXBP1,PRRC2C,VPS13A,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,THRA,TPM2,NR2C2,TUBB2A,UBE2H,KLC2,ZFAND5,WNK3,PLSCR4,RTN4,UBE3B,ACTR3B" MicroRNA hsa-miR-6799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-27 1.41E-23 6.87E-27 6.33E-26 92 679 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,DDR1,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,PITPNM3,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,DNAH9,SLC29A4,DUSP9,PHC2,TMTC1,APH1A,RASA4,PLEKHA1,MRNIP,IGSF6,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,BVES,IRAK3,AGBL5,ZNF491,IGF1,IBA57,SLC6A17,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,TBC1D25,ZNF713,PFKFB3,RETREG2,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,HES6,MYO18A,SLC2A5,ZKSCAN3,MCF2L2,DDN,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,TUBB2A,RPL7L1,BCL2L13,TSPAN11,KLC2,ZNF708,ZNF17,ZNF28,ZNF70,DPYSL5,EVI5,CIAPIN1,PARP11,TMEM63C" MicroRNA hsa-miR-708:mirSVR_highEffct hsa-miR-708:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.69E-27 1.50E-23 7.34E-27 6.76E-26 97 747 "ACADM,ACHE,AS3MT,RNF150,HACE1,BEGAIN,AMPH,ZFAT,OGT,PKP4,SEMA4G,ASPA,CACNA1G,C5,PTBP2,CAST,CLDN10,CD38,ARHGEF2,ZBED1,SRSF11,CNTFR,CLOCK,PREPL,GDA,SNCAIP,OSBPL3,SUSD5,FAM169A,DOCK4,GAPVD1,TMEM170A,GIT2,SV2B,ABCC5,YAF2,F8,CEP78,FGF1,NELFCD,NSG1,AP4B1,NEU3,GNG4,PLCD4,GSTT2,ATXN2L,KIF5A,MAT2A,LYRM9,MYO9A,NFE2L2,DNHD1,NTRK3,ZNF827,ZNF655,MTRF1L,SAMD9,TMEM260,ZIK1,C1orf109,ZNF615,MARCH1,MSANTD2,RDX,NUDT11,GSTCD,YY1AP1,LRRK2,CASC3,SEC31A,EPN2,PKNOX2,SIRT2,MAST1,SNAP25,MYO16,TTBK2,RGL1,ADHFE1,DMXL2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMEM9,TMPO,R3HDM1,ELP5,CCDC14,DHX33,PDSS2,KAT6A,JMJD1C" MicroRNA hsa-miR-936:PITA hsa-miR-936:PITA_TOP PITA 2.81E-27 1.57E-23 7.67E-27 7.06E-26 56 259 "FAM135A,DPP10,STX16,SCARB1,CFL2,MAP4K4,CNR1,RBM39,DOCK4,MAML1,ZBTB24,KLHL3,DRP2,TSPAN5,FAM13A,CALCRL,ETV1,FGF12,FAM49B,MEGF11,GABRB3,PCDH17,FAM222A,IGF1,KIF5A,SMAD1,MBNL1,AFDN,NEXMIF,NPTX1,GPR137C,GPR85,PIK3C2A,TRHDE,PTX3,TMEM255A,SLC25A36,ATXN2,TRA2B,HSPA4L,CPEB3,ABLIM3,CCDC88A,CPEB4,RBM26,CLASP2,NKAIN2,ERBIN,SYT1,TRIM2,SIRT1,EMSY,EVI5,NAV3,HNRNPA3,ADAMTSL3" MicroRNA hsa-miR-216a:PITA hsa-miR-216a:PITA_TOP PITA 2.99E-27 1.67E-23 8.15E-27 7.50E-26 66 363 "TRMT9B,TMEFF1,ZFYVE28,STK33,NCOA1,ATP1B3,JAZF1,CDH2,MAGI1,COL9A1,MATR3,PITPNC1,SPATA2,KLHL3,POM121,SEMA3D,FAM13A,MBNL2,KMT5B,EGR3,COPS4,TMEM35A,PAN3,RCAN2,MED12L,AFF2,MEGF11,CPLX2,PCDH17,PPARGC1A,KDM2B,PTPRT,FAM19A2,ADAMTS6,HNF4G,JAK2,KCND2,AFDN,HNRNPM,CNOT4,GPR85,ANKRD16,TMEM255A,FNIP1,SMPD3,FAM214B,SLC6A8,CPEB4,KDM4B,KDM3A,SP4,ARHGAP26,ELOVL4,ZC3H4,ANKRD28,ADGRL3,DMXL2,CUX2,RPGRIP1L,NR2E1,TRPS1,TBC1D15,ZIC1,SLC30A4,NAV3,PDSS2" MicroRNA hsa-miR-34a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.19E-27 1.78E-23 8.69E-27 8.00E-26 96 735 "AXIN2,ESYT2,AP2A1,AP2A2,APAF1,NCOA1,NUMB,CFLAR,BMP7,MTMR2,SEPT7,ZMYM4,LRRFIP1,EVI5L,MAGI1,FOXN3,CLTB,CLOCK,CSF1R,CYBB,GAPVD1,DAPK1,CDON,RCAN1,TOM1,DNAJB6,E2F5,EIF4G1,MRNIP,EPB41L2,ERBB2,ACSL4,NELFCD,APOPT1,ACSS1,POLL,PRRC2B,FUT10,TPPP,FICD,DDX19B,ATXN2L,HNF4G,IL6R,KCNH2,KIF2A,KIT,KTN1,L1CAM,STMN1,MAP4,MKLN1,MOV10,MYCN,CNOT4,OPA1,TREM2,TMOD2,XRN1,PPARA,MAPK3,QDPR,USP47,FIGN,CARF,MCMBP,COPZ1,CPEB3,SMARCA4,SMARCC2,PEG10,SPTAN1,RBM26,POGZ,STX1A,ZC3H4,SUPT5H,SYNE2,SYT1,MMS19,CAMTA1,FAM208A,SATB2,TPCN2,PUM2,SLC35G2,SIRT1,TP53BP2,TPM1,TSN,SSBP2,BCL2L13,RICTOR,RTN4,FXR1,SOCS4" MicroRNA hsa-miR-4312:mirSVR_highEffct hsa-miR-4312:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.79E-27 2.12E-23 1.03E-26 9.51E-26 79 516 "AP2A2,INTS2,ALK,SUGT1P4-STRA6LP-CCDC180,BCAS1,TNRC6C,CACNB4,KALRN,KRIT1,ARMC8,SLC4A8,CNRIP1,MROH8,ARHGEF10,PHF14,TCAF1,PABPC5,EXOG,IRAK4,GPHN,CEP85L,FDFT1,FER,APOPT1,KHDRBS3,ADAM28,LYVE1,RUNDC3A,ZNF276,ZNF638,GRIA2,NKD1,LRRCC1,SCIN,ITGAM,METTL21A,KIT,NCOA7,MAP2,MBD1,CNOT4,DNHD1,OXTR,PRKACB,FITM2,PSMA6,WDR25,CNTLN,RET,PBRM1,GSTCD,MCMBP,ABCA11P,ZNF331,AP1AR,SAFB,FERMT1,SLC6A8,ZNF430,MYH15,SNRPN,KDM4B,ERBIN,ADHFE1,PLCB1,TBL1X,SLC44A1,TMPO,SYNPO2,RUNDC3B,UBE2H,GORASP1,CELF4,ZNF154,ANKS1B,MAP3K12,FAM13C,DOCK8,PHTF2" MicroRNA hsa-miR-511-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-27 2.38E-23 1.16E-26 1.07E-25 56 261 "ADD2,PTCHD1,HACE1,TAOK1,MARCH3,ATP2A2,BACH1,CALM1,SEPT7,CFL2,IGLON5,PPP1R16B,DCAF8,DBT,YTHDC1,DMD,CDON,MBNL2,EIF5,KATNAL1,DLC1,FGF14,UBE2E3,AFF2,TRMO,MMADHC,CBX1,BVES,ZDHHC15,IL6ST,KLHL23,KCNQ3,KPNA5,LIFR,SMAD9,LYPLAL1,MKLN1,MYO5A,NCAM2,NELL2,NLGN3,CCSER2,SDK2,SATB1,CSRNP3,SCP2,FNIP1,KIF13A,ZHX3,ARHGEF9,PLCB1,TRIM2,KCNK12,ZNF138,ADAMTS9,KAT6A" MicroRNA hsa-miR-612:PITA hsa-miR-612:PITA_TOP PITA 4.46E-27 2.50E-23 1.22E-26 1.12E-25 51 214 "FZD9,HECW2,APBB2,USP37,FOXN3,COL4A5,CSNK1G3,RIMS4,ERC2,ZC3H11A,DPYSL2,CNNM1,EGR3,TENM1,SRRM1,AGAP2,CHL1,GABRB3,CPLX2,RUNDC3A,TTBK1,KDM2B,LPAR4,TOX2,BACH2,MIER3,IBA57,KCNB1,MEF2C,MPP2,PDE4D,PIK3R1,ANKRD16,PPP2R2B,RASGEF1B,MARCH1,RGS4,CASC3,CHD9,WDR37,SNCA,SP2,SS18,STX1A,SATB2,TCF12,ITGB3BP,THRA,SMARCAD1,EMSY,FRMD6" MicroRNA hsa-miR-3141:mirSVR_lowEffct hsa-miR-3141:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.61E-27 2.58E-23 1.25E-26 1.16E-25 76 481 "SYN3,OLMALINC,BEGAIN,AMPD2,LRFN1,SUGT1P4-STRA6LP-CCDC180,CALB2,RHBDL1,NFS1,ASIC3,EPS15L1,NRXN3,PPT2,MYL6B,NGEF,MAP4K4,IGLON5,ZNF385A,CST3,DBN1,ARMCX4,ELMO1,SEZ6L2,PHC2,RASA4,MRPL37,TUBB3,CORO2B,BAIAP2,AKAP3,POMT1,TMEM107,PDLIM5,RASL10A,CAMKK2,DLL3,HHIPL1,ACSS1,RNF165,UBE2QL1,SHISA6,CELF5,TJAP1,METTL21A,MAT2A,NRBP2,ZNF862,PCBP3,ZDHHC8,NALCN,SMOX,FXYD1,DIRAS2,CNNM2,BCAS3,ROGDI,TRIM68,RGS12,ATXN2,FAM81A,PEX26,LGI3,MAST1,RCOR3,MAPKBP1,TBL1X,ARHGAP9,GALNT17,TMEM9,NR2E1,LAT2,GUSBP1,MAP3K12,WNK3,ST7,RNF170" MicroRNA hsa-miR-142-3p:Functional MTI Functional MTI miRTarbase 5.49E-27 3.07E-23 1.49E-26 1.37E-25 68 389 "ZNF608,MTUS1,TAOK1,PHF12,APC,USP37,LGR5,CDC14B,ARNTL,ATP2A2,BACH1,PROM1,CALM1,SOCS6,ABCG2,HECTD1,CNN3,CPS1,CLOCK,CSNK1G3,SOCS5,PUM1,USP6NL,IP6K1,PITPNC1,CPEB2,DNAJB6,GOLT1B,EIF5,DCTN4,STX2,ACSL4,SUCO,SLC37A3,MSANTD4,FREM1,MALT1,RAB30,KAT7,FICD,IL6ST,ZNF678,KIF5A,MKLN1,AFF1,NEFH,STRN3,PPP2R2C,RIPOR1,PCMTD2,RPE,FNDC3A,PEX26,BTBD7,TROVE2,SS18,DIP2A,NSFL1C,SYPL1,PCDHGA10,PCDHGA2,ARL10,MTCH1,RICTOR,ZNF24,SIGLEC10,PDSS2,RNF170" MicroRNA "TACTTGA,MIR-26B:MSigDB" "TACTTGA,MIR-26B:MSigDB" MSigDB 6.46E-27 3.62E-23 1.76E-26 1.62E-25 58 283 "PLEKHH1,SLC24A4,ZNF608,AMPH,EP400,APC,USP37,SLC4A4,KALRN,TMEM184B,AKAP6,DAPK1,SPOCK2,PITPNC1,C2CD2L,POM121,SACS,USP3,EIF4G2,EIF5,PAN3,MEX3B,GABRB3,TNRC6A,ADAMTS6,IGF1,SMAD1,MAP2,MARK1,MITF,MMP16,BLOC1S2,MXI1,PCDH9,PFKFB3,PCDH18,FA2H,SH3KBP1,PTPN13,TTC13,RGS4,ZFHX4,RPS6KA2,RTN1,SALL1,MRAS,FBXO11,SLC12A2,BTBD7,TMCC1,CLASP2,LARP4,STAC2,PLCB1,VLDLR,CLDND1,WNK3,PHTF2" MicroRNA "TACTTGA,MIR-26A:MSigDB" "TACTTGA,MIR-26A:MSigDB" MSigDB 6.46E-27 3.62E-23 1.76E-26 1.62E-25 58 283 "PLEKHH1,SLC24A4,ZNF608,AMPH,EP400,APC,USP37,SLC4A4,KALRN,TMEM184B,AKAP6,DAPK1,SPOCK2,PITPNC1,C2CD2L,POM121,SACS,USP3,EIF4G2,EIF5,PAN3,MEX3B,GABRB3,TNRC6A,ADAMTS6,IGF1,SMAD1,MAP2,MARK1,MITF,MMP16,BLOC1S2,MXI1,PCDH9,PFKFB3,PCDH18,FA2H,SH3KBP1,PTPN13,TTC13,RGS4,ZFHX4,RPS6KA2,RTN1,SALL1,MRAS,FBXO11,SLC12A2,BTBD7,TMCC1,CLASP2,LARP4,STAC2,PLCB1,VLDLR,CLDND1,WNK3,PHTF2" MicroRNA hsa-miR-337-5p:mirSVR_lowEffct hsa-miR-337-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.76E-27 3.78E-23 1.84E-26 1.69E-25 66 368 "AXIN2,RNF150,MTA3,AGT,KCTD16,SPOP,CDC42BPA,LCORL,BLM,HECTD1,IQCK,CNRIP1,CREM,SNCAIP,SUSD5,VCAN,EARS2,PABPC5,PITPNC1,SNAP91,RAB39B,ABCC5,C3orf18,PIPOX,SMC2,PRELID3A,AP4S1,FAM95B1,RBPJ,NCOA7,MBD1,MEIS2,MID1,MYT1,HNRNPM,NFYA,TBC1D25,PDE1C,PNMA3,CYB561D1,YY1AP1,SNX22,ABCA11P,KCNIP3,CLIP1,TNFRSF19,COPZ1,KIF16B,ST6GAL1,ITPRID2,ZSCAN29,NECAB1,VPS13A,CAMTA1,FAM208A,ALG1,TPCN2,CLASP1,DICER1,AKTIP,TIMP4,TLR4,TP53BP2,ZBTB14,EML6,ACTR3B" MicroRNA hsa-miR-591:mirSVR_highEffct hsa-miR-591:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.77E-27 4.35E-23 2.11E-26 1.94E-25 73 449 "ACADM,NCKAP5,ADGRF5,ALCAM,CD38,CDO1,MS4A7,CNOT8,QKI,VAC14-AS1,DZIP3,IST1,DGKG,RHOBTB1,ZNF582-AS1,DNAH9,DMTF1,ARRDC4,AASDH,WDPCP,EDN1,SRRM1,ABCA8,FGF11,MEX3B,STAMBP,OGA,MEGF11,GCNT2,ADAM28,TXNL4A,GSTM5,GUCY1B1,MIER3,INSM1,KLHL23,KCNN3,KIT,PAXBP1,MBNL1,ADAM22,NTRK2,PDE4D,GPR85,EPB41L4B,RANBP3L,MAPK10,SUSD4,RET,KLHL11,RNASEL,SETD5,LRRK2,PPM1E,FBXO11,LIMCH1,MBD5,ZC3H13,ATP10B,ASTN2,ZEB1,PCDHB6,FRYL,FAM200B,PMS2CL,ERCC6L2,SYNPO2,RUNDC3B,TUBB2A,ZNF177,MFF,FXR1,FAM198A" MicroRNA hsa-miR-886-3p:mirSVR_lowEffct hsa-miR-886-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.98E-27 4.46E-23 2.16E-26 1.99E-25 75 473 "ABR,AXIN2,BEND6,MTA3,AMPD2,EP400,CDK10,MARK4,ATP1A1,DPY19L3,CALB2,KALRN,HAP1,CBS,METTL6,CBFA2T2,DGKI,DLGAP1,EPS15L1,TMEM184B,MAP4K4,CABP1,AKAP12,RIMS2,GPSM1,B3GAT3,LYPD1,GUCD1,PLPPR4,SLC29A4,DPH1,DPYSL2,DTNB,EDNRB,MBNL2,RABEPK,RACK1,ZNF589,ERGIC3,GLYR1,C1QL4,CLASRP,GSTM5,LRRC25,KCNB1,MBP,MEIS2,PTOV1,PCBP3,P2RX7,SDK2,PPARA,WBP1L,CCDC40,RNH1,ARMC5,FOXRED1,FERMT1,SLC11A1,SNRPN,FAM219A,NFASC,ADHFE1,ZC3H4,VPS13A,ADAMTS17,TPCN2,HIF3A,DICER1-AS1,ACTR6,PPIL6,RPRM,MEIS3,SEMA3B,ST7" MicroRNA hsa-miR-578:PITA hsa-miR-578:PITA_TOP PITA 9.01E-27 5.04E-23 2.44E-26 2.25E-25 63 337 "KCNH8,PCDH19,SPOP,LRCH2,CDC14B,RGS20,NCOA1,NUMB,CAMK2G,RUNX1T1,LDB2,CLCN3,CNR1,BAG4,KCTD8,ALKBH8,DMD,HIPK3,RCAN2,EPHB1,MRVI1,ACSL4,FGF12,FLT1,ARFIP1,SESN1,PCDH17,PPARGC1A,LPAR4,GRIA2,CIT,STXBP5,MEF2C,MEIS2,MITF,AFF1,MXI1,NF1,NPTX1,ZNF827,RETREG1,PID1,TMEM255A,RDX,SETD5,RORB,PPM1E,TRIM67,CPEB4,HECW1,RGL1,SYPL1,TCF4,DOCK9,CSMD1,TNS1,TRPS1,SGK3,FLRT2,ZFAND5,SLC38A1,PDSS2,MSRB3" MicroRNA hsa-miR-377*:mirSVR_highEffct hsa-miR-377*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.09E-27 5.08E-23 2.46E-26 2.27E-25 83 573 "ASIC1,DPY19L2P4,PITPNM2,FGD2,PHYHD1,ARRB2,NCOA1,N4BP2L1,VXN,CLDN10,ARHGEF2,RAB33A,ABCG2,FHL5,IQCK,ARMC8,MYRIP,UBXN2A,CYBB,HEPH,MYEF2,RHOBTB1,DNM1,DMTF1,TOM1,EDNRB,C8orf37,VPS13B,ERBB2,FAM198B,GORAB,FGF11,SLC37A3,FYN,ZNF234,GHR,ZNF276,CCDC184,RNFT2,ADAMTS6,MSL1,MYLK2,CREG2,CLEC18A,MSR1,RTL5,NFE2L2,PIGG,CNTLN,ZSCAN32,ZDHHC14,RNASE1,TMLHE,ROBO1,ATP8B4,GLDN,TCP11L1,SCN7A,MYO18A,CNKSR2,SEC31A,FAM214B,PKNOX2,ZNF334,TET1,MBD5,NFASC,SYN1,SYT1,SLC37A2,DOCK9,HIF3A,TIAM1,ERCC6L2,TRIO,STXBP4,RUSC1,DPYSL5,LAMP5,TMEM178A,CASC15,TRAM2-AS1,NETO1" MicroRNA hsa-miR-4266:mirSVR_highEffct hsa-miR-4266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.79E-27 5.48E-23 2.65E-26 2.44E-25 78 511 "KCTD16,OSBPL1A,OGT,PHF12,PARG,ADGRB2,KSR1,LURAP1,RUNX1T1,ZMYM4,CHN2,RAB28,CLTC,COL11A2,ANKRD44,ZSCAN23,CYBB,KATNAL2,TCAF1,FBXL5,GOLT1B,EDNRA,EIF4G2,DNAJC27,MRVI1,NRN1,FCGRT,PDLIM5,GABRB3,GAD1,DISC1,GLUL,GRIA2,DIDO1,ZNF546,ZIC5,ZNF678,INPP5B,KCNN2,PIK3AP1,MBP,XRRA1,COL28A1,MYO7A,SFR1,GNG2,ZNF655,RETREG1,RASGEF1B,PRKACB,PSMA6,TMEM255A,FAT4,ABCA11P,SCN2B,CHD9,R3HDM2,FAM214B,SLC12A2,SMARCA4,KDM4C,CLSTN2,NXT2,TTBK2,C12orf76,TACR1,TBCEL,FBXW11,ARHGAP9,HEY1,R3HDM1,RUSC1,TTTY15,FSTL5,ZNF225,RNF103,ST7,ZNF30" MicroRNA hsa-miR-671-5p:mirSVR_highEffct hsa-miR-671-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-26 5.97E-23 2.89E-26 2.66E-25 85 600 "ESYT2,PTCHD1,KCTD16,CCDC146,PHF12,APC,DST,CASTOR3,CAPN3,VXN,CBS,LDB2,C1orf52,LOC730101,CFL2,EPS15L1,ARMC8,SUMF2,MYRIP,FAM171B,CRY2,SEC24C,RIMS2,DAPK3,SACS,EDN1,PHC2,ANKRD46,EGFR,KMT5B,NRN1,DLC1,RACK1,PDLIM5,CELF1,MSANTD4,FAM120B,DISC1,ADGRA3,MCHR1,CLASRP,HMGCL,HNMT,KIT,CAMK2N2,ASPRV1,MAN2A2,MARK1,LRP1B,SHC3,PCSK1,PLXNB1,EPB41L4B,GRAMD1C,CNTLN,PTPRD,CASTOR1,ZSCAN2,FAT4,ROBO2,ATP8B4,LRRK2,ATXN7,GALNT10,ARX,R3HDM2,WDR37,SEPT3,WSCD1,SATB2,SYNE1,USP32P1,CYB561A3,PIK3R5,RPL7L1,VSNL1,PCDH20,ZNF189,FTSJ1,STOX2,HPS4,FZD3,NLRP3,TIGD6,FRMD6" MicroRNA hsa-miR-216b:PITA hsa-miR-216b:PITA_TOP PITA 1.07E-26 5.98E-23 2.89E-26 2.66E-25 63 338 "RALGAPA1,CLK4,PTCHD1,PKP4,NRP2,VXN,RUNX1T1,SYNGR3,CFL2,SOCS6,CRY2,CLIP3,LRIG1,FAM131B,DOCK4,MATR3,MAML1,GUCD1,CPEB2,PDCD6IP,MBNL2,TENM1,EPB41,SUCO,AFF2,ARFIP1,PCLO,DDX19B,HLF,ZIC5,CREG2,MEF2C,MID1,AFF1,NFIX,CNTN3,PFKFB3,SCHIP1,SDK2,PRKAB2,MAPK9,RELN,RBBP6,RDX,RPE,TNFRSF19,SCAF8,SGK1,FNDC3A,PPP4R3A,MBD5,TMCC1,FAM126B,SOX11,TEX2,ZNF423,LARP4,ERBIN,TCF4,CUX2,SYNE1,KCNT2,ADAMTS9" MicroRNA hsa-miR-633:PITA hsa-miR-633:PITA_TOP PITA 1.17E-26 6.55E-23 3.17E-26 2.92E-25 56 266 "GALNT13,PCDH19,CACNA1A,CAMK2G,PRC1,KRIT1,USP6,B4GALT6,CNN3,AKAP6,AHCTF1,MYRIP,CPEB2,TENM1,EPB41L2,DLC1,OLFM1,ATP2C1,PPARGC1A,GPD2,STON1,MIER3,HLF,GABARAPL2,ZIC5,MBNL1,KITLG,NFE2L2,NFIX,NOVA1,GPR137C,XRN1,PCDH18,STRN3,LRP12,DRAM2,MTMR10,PTPRD,ROBO1,RORB,FBXO11,NLGN1,CDK19,NKAIN2,NECAB1,SYT1,ANKRD28,ANKRD12,TCF4,DICER1,NR2C2,TRPS1,UBE2H,UBE3A,TMEM237,KAT6A" MicroRNA hsa-miR-382:PITA hsa-miR-382:PITA_TOP PITA 1.18E-26 6.57E-23 3.18E-26 2.93E-25 57 276 "NDRG2,PWWP2A,BEND6,PKP4,EIF4G3,SOCS6,LHX2,CLTC,QKI,CRHBP,SEC24C,MATR3,YTHDC1,DMD,HIPK3,YAF2,MBNL2,PLEKHA1,AMOTL2,AFF2,NBEA,CELF1,GABRB3,DHRS4,ZHX1,NEGR1,ZIC5,MBNL1,MEST,MID1,NEXMIF,PCDH9,PRTG,PDE1C,PDPK1,GPR85,LRP12,EPB41L4B,RPE,SGK1,SHC4,BTBD3,SSTR1,SEPT3,SYT1,CAMTA1,KLHL4,CUX2,DICER1,EIF4ENIF1,UBE2H,UBTF,TMEM237,SMARCAD1,NAV3,KCNAB1,NETO2" MicroRNA hsa-miR-720:mirSVR_lowEffct hsa-miR-720:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-26 6.72E-23 3.25E-26 2.99E-25 74 464 "DGCR6,LTBP4,CDK10,CCAR2,DPY19L3,ADGRB2,NRP2,ARHGEF7,CASTOR3,CACNA1A,CALB2,SPAG9,USP6,CACNA2D2,LHX2,NRXN3,SLC4A8,CRY2,RGS6,INTS1,SPOCK2,DNM1,RPS6KL1,DPH1,SPEG,CLVS1,RPS6KC1,FCGRT,FGF14,SEPT9,TUBGCP4,USP19,STARD3,WDFY3-AS2,GRM2,ZNF496,KCNJ16,KHK,LAMP2,NCOA7,MN1,PCSK5,KCTD15,PLCD1,ANKRD16,IRX1,PCDHB17P,VSTM2L,PTK2,PTPRB,SETD5,CCDC25,SH3GL3,ARFGAP1,ZSWIM8,ATP10B,PBLD,CAMTA1,USP32P1,SLC44A1,PIK3R5,TPM2,SMUG1,TTC3,SGK3,GORASP1,PLPPR2,ATP6V0E2,SH3GLB2,TMEM178A,PCBP4,DOCK8,TIGD6,SPATA13" MicroRNA hsa-miR-6779-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-26 7.00E-23 3.38E-26 3.11E-25 90 667 "XKR4,PLEKHH1,TXNDC16,AK2,TRMT9B,PHF12,AQP6,ARRB2,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,PRRC2B,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-489:PITA hsa-miR-489:PITA_TOP PITA 1.44E-26 8.07E-23 3.90E-26 3.59E-25 48 192 "XKR4,CCDC85A,KLHL13,PCDH19,TAOK1,SEMA6A,NCOA1,ATP1B3,ATP2B2,LURAP1,CLOCK,SEC24C,GRIN3A,NYAP1,FRY,PCOLCE2,TMEM35A,EMX2,EYA1,CELF1,FUT9,GABRB3,SPIN1,SERP2,MIER3,KCNN2,IPO5,PACRG,MAT2A,MITF,HS6ST3,MXI1,MYO5A,NTRK3,PDE1B,PIK3R1,CEP41,TMEM260,RAP1GDS1,GLDN,PPM1E,SHC4,CPEB4,SMARCA4,FAM126B,SYP,DICER1,CADM2" MicroRNA hsa-miR-454-3p:Functional MTI Functional MTI miRTarbase 1.62E-26 9.05E-23 4.37E-26 4.02E-25 68 396 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,DAPK1,SEC16A,MED12,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,MRPL37,ACSL4,DLC1,FKTN,POLR1B,SEC23B,FLNC,CINP,MSANTD4,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PTPRG,UBR7,PTGR2,CLIP1,BTBD3,ATF7IP,TET1,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,SIK3,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1" MicroRNA hsa-miR-1825:mirSVR_highEffct hsa-miR-1825:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-26 1.32E-22 6.36E-26 5.85E-25 75 481 "ACHE,CLK4,BEND6,ABCD2,PCDH10,UPRT,ARRB1,SEC11C,CDH2,CFL2,CNOT8,CLCN3,ARMC8,SLC35F1,CTH,GIT2,ARMCX4,ZNF804A,DTNA,PHC2,KLHL5,PHF20L1,EXTL2,FER,CELF1,GALC,KIAA1841,TUBGCP4,WASHC2A,PCDH17,SPIN1,ZNF782,PCLO,GRIN2C,HAS2,SCIN,KIT,AQP11,POC1B,MITF,LYRM9,NBL1,NPTX2,NTRK2,PDE1C,GPR85,NLGN3,MAPK10,HYDIN,APTX,EML5,FAM184A,PRRT2,FIGN,RFX3,CARF,ROBO2,ATP8B4,FNDC3A,SP2,ITPRID2,SS18,ERBIN,KLHL7,VPS13A,FBXW11,SMG6,SZT2,TIAM1,UGT8,ZNF17,TMEM237,KCNAB1,RTN4,JPH3" MicroRNA hsa-miR-517a:mirSVR_lowEffct hsa-miR-517a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.51E-26 1.40E-22 6.77E-26 6.23E-25 64 354 "ADGRF5,OGT,CCDC146,PKP4,KCNAB2,APBB2,TNRC6C,PPFIA3,LGR5,EIF4G3,USP6,ARHGEF2,DGCR9,FAM189A2,GALNT9,DOCK4,MATR3,KCTD8,DAPK1,JAKMIP2,LYPD1,SV2B,DTNA,RASGRP1,ENPP6,PTK2B,FLT1,GALNT15,DISC1,FERMT2,RNF165,NKD1,A1BG-AS1,P2RY13,OXTR,PDE4D,PFKFB4,SEMA5B,PPP2R2C,EPDR1,MAPK9,PTPRH,RASGRF2,UBR7,RGS12,LGI2,C12orf49,SHC4,DHX30,SLC12A2,RCOR3,STAU1,STXBP1,UGT8,TBC1D15,SLC47A2,CELF4,STOX2,PRDM8,RNF103,MPPE1,WNK2,EPM2A,ACTR3B" MicroRNA hsa-miR-7:PITA hsa-miR-7:PITA_TOP PITA 2.58E-26 1.44E-22 6.95E-26 6.40E-25 52 231 "ELFN2,OGT,PPFIA3,CDC14B,SLC4A4,ATP2B2,MAGI1,FOXN3,CNOT8,CNN3,CRY2,CLIP3,FAM131B,BOC,SPATA2,DPYSL2,EGR3,ERBB4,ACSL4,PTK2B,FGF13,GAD1,ADAM11,CHAMP1,PDE4B,PDE4D,CCSER2,PLEC,MAPKAP1,STRN3,PRKCB,MAPK4,PTK2,OXR1,SEMA6D,SATB1,SCN2B,R3HDM2,WDR47,SNCA,FAM126B,CLASP2,NECAB1,ZC3H4,ANKRD28,ANKRD12,TCF4,TCF12,SZT2,FLRT2,ZBTB38,RGS7BP" MicroRNA "CTCAGGG,MIR-125B:MSigDB" "CTCAGGG,MIR-125B:MSigDB" MSigDB 2.76E-26 1.55E-22 7.44E-26 6.85E-25 59 301 "ABR,ASIC1,ABHD6,ADD2,LRFN2,MTUS1,USP37,MADD,SLC4A4,ADGRB1,MTMR3,SCARB1,ZNF385A,ENTPD4,NCOR2,FAM131B,IST1,IP6K1,ELMSAN1,DCTN1,ABCC5,PHC2,CNNM1,SEMA4D,GGT7,GRB10,ATOH8,MAN1B1,LIFR,MAP6,ADAM11,MEIS2,MSI1,MYT1,RETREG2,DRAM2,MASP1,DPF2,RET,EMID1,SCN2B,CASC3,CPEB3,MYO18A,ST6GAL1,ABTB1,SOX11,SPTB,IQSEC2,SYN2,SATB2,DICER1,AP4E1,TRPS1,SLC35A4,KLC2,CRB2,SLC17A7,SOCS4" MicroRNA "CTCAGGG,MIR-125A:MSigDB" "CTCAGGG,MIR-125A:MSigDB" MSigDB 2.76E-26 1.55E-22 7.44E-26 6.85E-25 59 301 "ABR,ASIC1,ABHD6,ADD2,LRFN2,MTUS1,USP37,MADD,SLC4A4,ADGRB1,MTMR3,SCARB1,ZNF385A,ENTPD4,NCOR2,FAM131B,IST1,IP6K1,ELMSAN1,DCTN1,ABCC5,PHC2,CNNM1,SEMA4D,GGT7,GRB10,ATOH8,MAN1B1,LIFR,MAP6,ADAM11,MEIS2,MSI1,MYT1,RETREG2,DRAM2,MASP1,DPF2,RET,EMID1,SCN2B,CASC3,CPEB3,MYO18A,ST6GAL1,ABTB1,SOX11,SPTB,IQSEC2,SYN2,SATB2,DICER1,AP4E1,TRPS1,SLC35A4,KLC2,CRB2,SLC17A7,SOCS4" MicroRNA hsa-miR-485-5p:Non-Functional MTI (Weak) Non-Functional MTI (Weak) miRTarbase 2.85E-26 1.59E-22 7.66E-26 7.06E-25 81 557 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,CEP126,LRFN1,CDC42BPA,AQP6,ARHGDIA,ZNF583,SYNJ2,CCNT1,SLC16A4,NRXN3,SUMF2,SLC35F1,CRY2,IPCEF1,RIMS4,UBXN2A,KIAA0408,MYADM,TMEM170A,ELMSAN1,DNAH9,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,ZNF589,ATP13A4,DOT1L,PPARGC1A,CRCP,GPR75,GLUL,ZNF638,GPT2,BVES,ATOH8,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,SLC11A2,PCSK1,PSD,APTX,MTMR10,TMEM145,QDPR,KLHDC8A,GSTCD,PTGR2,AMBRA1,SLC2A5,SEPHS1,CDK19,MCF2L2,DDN,LHPP,SYNE2,FAM208A,TPCN2,USP22,SLC19A3,PCDHA6,HIF3A,ARL10,SSBP2,XPO1,EVI5,URM1,MPPE1" MicroRNA hsa-miR-621:mirSVR_highEffct hsa-miR-621:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.97E-26 1.66E-22 7.98E-26 7.35E-25 68 400 "CLK4,ACTN1,KDM5D,CCDC85A,SEMA6A,ALCAM,ANK2,NUMB,ARHGEF7,CFL2,AKAP7,PREPL,HAPLN1,ANKRD44,CS,DZIP3,GREB1,CCDC144A,MYEF2,CASP8AP2,SEMA3D,FAM13A,EPHB1,FOXF2,IP6K2,SYNCRIP,AKAP3,GPD2,SLC2A6,ZHX1,MIER3,RBPJ,JAK2,KCNH2,NF1,PDE4D,GPR85,PFKFB2,PFKFB3,EPB41L4B,VPS13C,ZFHX4,MEG3,ZNF568,AP1AR,ATXN7,KIF16B,WDR37,SNCA,HECW1,VPS13A,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TMPO,FAM124A,TP53BP2,TRIO,CLHC1,VSNL1,DOCK8,RNF170,SNX14" MicroRNA "ATGTTAA,MIR-302C:MSigDB" "ATGTTAA,MIR-302C:MSigDB" MSigDB 3.21E-26 1.80E-22 8.63E-26 7.94E-25 52 232 "ABR,SPOP,GPRASP2,LRCH2,NUMB,NRP2,MAGI1,CREM,PHF14,GAPVD1,MATR3,KCTD8,ELMSAN1,SNAP91,DLX1,CPEB2,DNAJB6,EDNRB,PHF20L1,GPHN,ATP2C1,KHDRBS3,ST6GALNAC3,GABRB3,GAD1,PPARGC1A,LIFR,MBNL1,MEIS2,MYT1,NFIX,PCDH9,PDE4D,PPARA,PPP2R2C,PPP2R5E,PPP5C,PTPRE,KHDRBS2,BTBD3,USP33,SOX3,SOX11,SP4,CDK19,ANKRD12,ADGRL3,TBL1X,SIRT1,ZFPM2,USP1,FXR1" MicroRNA hsa-miR-3194:mirSVR_highEffct hsa-miR-3194:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-26 1.85E-22 8.91E-26 8.20E-25 66 378 "DGCR6,ADD2,PWWP2A,SMIM17,SUGT1P4-STRA6LP-CCDC180,CASTOR3,CFAP410,KALRN,LARGE1,CSF2RA,ARHGAP24,ARMCX4,SNAP91,RAB39B,DNM1,DTNA,AMOTL2,HVCN1,OGA,ERAP1,DISC1,PCLO,GRM2,SOX21,HP,MSL1,SCIN,KCND2,KIFC3,PAXBP1,ZFYVE27,AQP11,MBNL1,TM6SF1,MOV10,NDP,DUSP26,SEMA5B,VSTM2L,PRKAB2,CNTLN,SLC25A48,RGS12,EPHA10,SPIN3,GLDN,MEG3,KIF16B,HKDC1,FNDC3A,SYBU,ABLIM3,BTBD3,KANSL3,ELMO2,BTBD7,FNBP1,LARP4,CEP68,RGL1,SYN2,HIF3A,TEK,DNAH7,DICER1,LAMP5" MicroRNA hsa-miR-553:mirSVR_highEffct hsa-miR-553:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.45E-26 1.93E-22 9.26E-26 8.53E-25 68 401 "OSBPL6,AMPD3,OGT,CDC42BPA,ARNTL,MARCH3,SLC4A4,PTBP2,METTL6,CCNH,SEPT7,NRXN3,HECTD1,FHL5,PCYT1B,SLC4A8,GAL3ST1,DCAF4,TM9SF4,C2CD2L,USP3,DPH1,AASDH,RASGRP1,C8orf37,PAN3,DNAJC27,SCML2,ZSCAN30,AMOTL2,FOXO3,NEU3,ARFIP1,GHR,PPARGC1A,TNRC6A,TDRKH,GPR12,ELOVL5,ZNF678,LAMP2,NCOA7,SMAD9,PDE4D,NALCN,PPP2R2B,SPDL1,TMEM260,PTPRG,PRRT2,GTDC1,CLIP1,FNIP1,SH3BGR,SHC4,NLGN1,FAM81A,PPP4R3A,MBD5,NXT2,SYPL1,CUX2,RPRM,VLDLR,ZNF138,SMARCAD1,FIP1L1,HNRNPA3" MicroRNA hsa-miR-199b-3p:TargetScan hsa-miR-199b-3p TargetScan 3.48E-26 1.95E-22 9.33E-26 8.59E-25 64 356 "PLEKHH1,KCTD16,HACE1,ARHGAP20,NCOA1,FUBP1,ARHGEF2,CFL2,QKI,ARMC8,COL4A5,RNF14,ANKRD44,CCDC144A,LIN54,KLHL3,DTNA,EBF1,HIPK3,FRY,ERBB4,CEP85L,MED12L,PSD2,FAM49B,CELF1,FUT9,HHIPL1,IQGAP2,GCNT2,PCDH17,LPAR4,HNMT,CELF5,IGF1,KTN1,MBNL1,MEF2C,MEIS2,MMP16,NOVA1,PDE4B,PURG,PPM1B,PPP2R5E,PTPRG,FIGN,RFX3,RORB,CCDC88A,ATF7IP,CPEB4,KDM4B,KDM3A,LMO3,PLCB1,FBXW11,NACC2,NAV3,PCBP4,ADAMTSL3,FXR1,DPF3,GAN" MicroRNA hsa-miR-199a-3p:TargetScan hsa-miR-199a-3p TargetScan 3.48E-26 1.95E-22 9.33E-26 8.59E-25 64 356 "PLEKHH1,KCTD16,HACE1,ARHGAP20,NCOA1,FUBP1,ARHGEF2,CFL2,QKI,ARMC8,COL4A5,RNF14,ANKRD44,CCDC144A,LIN54,KLHL3,DTNA,EBF1,HIPK3,FRY,ERBB4,CEP85L,MED12L,PSD2,FAM49B,CELF1,FUT9,HHIPL1,IQGAP2,GCNT2,PCDH17,LPAR4,HNMT,CELF5,IGF1,KTN1,MBNL1,MEF2C,MEIS2,MMP16,NOVA1,PDE4B,PURG,PPM1B,PPP2R5E,PTPRG,FIGN,RFX3,RORB,CCDC88A,ATF7IP,CPEB4,KDM4B,KDM3A,LMO3,PLCB1,FBXW11,NACC2,NAV3,PCBP4,ADAMTSL3,FXR1,DPF3,GAN" MicroRNA hsa-miR-532-5p:PITA hsa-miR-532-5p:PITA_TOP PITA 3.53E-26 1.97E-22 9.45E-26 8.70E-25 51 223 "PWWP2A,ZNF608,CAMK2G,SLC25A14,CAPN3,CAST,DCLK1,ZMYM4,DLGAP2,CACNA2D2,FOXN3,ARMC8,SLITRK5,SEC24B,SUCO,UBE2E3,NBEA,CHL1,PCDH17,CIT,NEGR1,NKD1,IBA57,IPO5,KTN1,MAP2,NDP,GPR137C,PCDH9,PCSK1,PDE1C,OLA1,PIK3C2A,PURG,PTPRB,OXR1,PPM1E,CPEB3,CHD9,SLC8A1,BTBD7,CXXC4,PDZD2,ELOVL4,SYN2,ANKRD28,TRIM2,XPO1,PCDH20,LYPD6,HNRNPA3" MicroRNA hsa-miR-3200:mirSVR_highEffct hsa-miR-3200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.68E-26 2.06E-22 9.87E-26 9.08E-25 67 390 "SYN3,ADD2,DPY19L2P4,AP2A2,USP35,CCDC146,TNRC6C,ALDH7A1,RUNX1T1,LDB2,C1orf52,CLCN3,CNGA3,AKAP6,CSNK1G3,RIMS2,DOCK4,KIAA0319,ABCC5,DNM1L,AASDH,USPL1,ACSL4,RACK1,POLR1B,RGPD5,FLT1,C2orf88,PDLIM5,MEGF10,ERAP1,LYVE1,KDM2B,MAP4K5,TNFAIP8L3,KCND2,MAT2A,MATN2,MITF,LOC100128398,ZNF655,PLCL1,PURG,PSAT1,WDR25,ZIK1,ZNF793,OXR1,RGS3,RORB,ABCA11P,CNKSR2,SLC12A2,RCOR3,ZNF415,ZBTB43,POGZ,RGL1,ADHFE1,SYNE2,DNMBP,ITGB3BP,UBE2H,AGMO,EPM2A,FZD3,HNRNPA3" MicroRNA hsa-miR-223-3p:TargetScan hsa-miR-223-3p TargetScan 3.73E-26 2.09E-22 1.00E-25 9.20E-25 57 282 "PLEKHH1,PKP4,APC,MARCH3,NCOA1,MTMR2,PTBP2,SCARB1,NRXN3,HDAC4,DOCK2,PHF20L1,ARMCX1,FOXO3,ANKFY1,CSPG5,COPS8,GLUL,KCNMB4,HLF,HNMT,RBPJ,KIAA1755,IL6ST,INPP5B,LMO2,GPR155,MAP4,MBNL1,MEF2C,MMP16,LAYN,NDP,NOVA2,PAX6,PDE4D,PDPK1,PFKFB3,PIK3C2A,NLE1,LRP12,PRKACB,CEP41,GTDC1,RORB,FBXW7,MCMBP,SCAF8,CPEB3,ERC1,NFASC,C18orf54,CBX5,AGMO,LYPD6,KAT6A,NLRP3" MicroRNA hsa-miR-379-3p:TargetScan hsa-miR-379-3p TargetScan 3.76E-26 2.11E-22 1.01E-25 9.27E-25 50 214 "C3orf14,RNF150,ALCAM,C6orf89,APBB2,INSYN2B,DOCK11,CDH2,NRXN3,ARMC8,AKAP5,PLCXD3,PYGO1,MATR3,ELMSAN1,ENPP6,ERBB4,SEC24B,ATP6V1H,MSANTD4,KDM2B,PSIP1,FRMD5,BACH2,KCNB1,KCNN3,CHIC1,MEIS1,P2RY1,GPR173,GNG2,SDK2,PPP2R2C,ANKHD1,PTPRD,GTDC1,RPE,SALL1,SATB1,HSPA4L,NLGN1,MPRIP,CLASP1,AP4E1,CBX5,RGMB,FZD3,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-1285:PITA hsa-miR-1285:PITA_TOP PITA 3.76E-26 2.11E-22 1.01E-25 9.27E-25 50 214 "FZD9,HECW2,APBB2,USP37,FOXN3,COL4A5,CSNK1G3,RIMS4,ERC2,ZC3H11A,DPYSL2,CNNM1,EGR3,TENM1,SRRM1,AGAP2,CHL1,GABRB3,CPLX2,RUNDC3A,TTBK1,KDM2B,LPAR4,TOX2,BACH2,MIER3,IBA57,KCNB1,MEF2C,MPP2,PIK3R1,ANKRD16,PPP2R2B,RASGEF1B,MARCH1,RGS4,CASC3,CHD9,WDR37,SNCA,SP2,SS18,STX1A,SATB2,TCF12,ITGB3BP,THRA,SMARCAD1,EMSY,FRMD6" MicroRNA hsa-miR-411-3p:TargetScan hsa-miR-411-3p TargetScan 3.76E-26 2.11E-22 1.01E-25 9.27E-25 50 214 "C3orf14,RNF150,ALCAM,C6orf89,APBB2,INSYN2B,DOCK11,CDH2,NRXN3,ARMC8,AKAP5,PLCXD3,PYGO1,MATR3,ELMSAN1,ENPP6,ERBB4,SEC24B,ATP6V1H,MSANTD4,KDM2B,PSIP1,FRMD5,BACH2,KCNB1,KCNN3,CHIC1,MEIS1,P2RY1,GPR173,GNG2,SDK2,PPP2R2C,ANKHD1,PTPRD,GTDC1,RPE,SALL1,SATB1,HSPA4L,NLGN1,MPRIP,CLASP1,AP4E1,CBX5,RGMB,FZD3,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-1244:PITA hsa-miR-1244:PITA_TOP PITA 3.83E-26 2.14E-22 1.02E-25 9.43E-25 55 262 "KCNH8,GALNT13,TMEFF1,BCL7A,CALB1,CALM1,DCLK1,QKI,MAML1,MTX3,WDR20,DYNC1I1,TENM1,PAN3,GPHN,ERBB4,EYA1,MED12L,HVCN1,KHDRBS3,GABRB3,GPR37,TPPP,ZHX1,AGFG1,MBNL1,MEIS2,LAYN,NOVA1,PPP2R5E,MAPK4,SNRK,PTN,ZSCAN32,PTPRD,PTPRN,EXD2,CPEB3,FBXO11,SMARCC2,KDM3A,ZNF423,CLASP2,ITPRID2,NXT2,PLCB1,ANKRD28,FBXW11,SSBP2,UBE3A,VLDLR,EVI5,FXR1,DPF3,SOCS4" MicroRNA hsa-miR-1246:PITA hsa-miR-1246:PITA_TOP PITA 3.99E-26 2.23E-22 1.07E-25 9.81E-25 52 233 "AXIN2,PWWP2A,PCDH19,TAOK1,SEMA6A,USP37,RNF182,CALB1,CAMK2G,LDB2,LONRF2,CDH2,QKI,AKAP6,PLCXD3,IP6K1,DYNC1I1,YAF2,MBNL2,EGR3,SLC43A2,ERBB4,CLVS1,CPLX2,MSTN,ARFIP1,SESN1,FERMT2,ADAMTS6,MIER3,LSS,CHIC1,ZC3H12B,NTRK2,WBP1L,PTCH1,TMEM255A,RDX,ROBO1,CSRNP3,LRFN5,FNDC3A,SEPHS1,CCDC88A,SLC12A2,FAM126B,ZNF423,SYN1,TCF4,FAM155A,KCNAB1,FRMD6" MicroRNA hsa-miR-670-3p:TargetScan hsa-miR-670-3p TargetScan 4.01E-26 2.24E-22 1.07E-25 9.85E-25 68 402 "ABHD6,C3orf14,NDRG3,ADORA2A,PKP4,APBB2,MARCH3,MARK4,NCOA1,CCNT1,MAGI1,CCPG1,NRXN3,FHL5,RTTN,IPCEF1,APPL1,CYBB,ARHGAP24,HDAC4,HEYL,DENND4A,NSRP1,PDLIM5,MSANTD4,GHDC,HIGD1B,ERAP1,KIAA1958,GPR12,PTPRT,KAT7,LINGO1,RASSF8,RBPJ,IL6ST,ITGA7,KCNN3,KCNQ3,NCOA7,MBNL1,ENPP2,PRKACB,CEP41,CNNM2,APTX,PEX2,RAP1GDS1,REV3L,PBRM1,RNASEL,C12orf49,ALG9,RORB,CSRNP3,DZIP1,FAIM2,FAM126B,BDP1,ELOVL4,KIAA0930,CBX5,RUNDC3B,RTN4,HNRNPA3,RSPRY1,FXR1,GAN" MicroRNA hsa-miR-4668-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-26 2.24E-22 1.07E-25 9.85E-25 68 402 "XKR4,AXIN2,SLC24A4,ZNF608,OGT,PHF12,ZBTB10,LDHD,AP1M1,CALM1,USP2,CACNA2D2,HECTD1,CNN3,RTTN,HAPLN1,USP6NL,MTX3,DPP6,EDIL3,DLC1,FECH,FGF12,TMEM164,PPARGC1A,CRCP,RAB30,TNRC6A,DCLK2,FICD,NEGR1,KCNB1,STMN1,MAT2A,MEF2C,NFYA,IGSF11,OCRL,ZNF713,PDE4D,PDPK1,PKM,EPB41L4B,DRAM2,RASGEF1B,RAP1GDS1,RFX3,SLC25A36,GSTCD,KIAA0895L,ATAT1,ZNF568,NCBP3,SH3BP2,SP4,UHRF1BP1L,SPART,NXT2,SLC44A1,NACC2,RGMB,TRPS1,TSC1,UBE2H,SLC30A4,ITM2C,WNK3,GAN" MicroRNA hsa-miR-4789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-26 2.39E-22 1.14E-25 1.05E-24 58 293 "TAOK1,STX16,ATP2A2,BACH1,CA8,TBRG4,B4GALT6,COL9A1,BAG4,ANKRD44,PLXNA4,SPOCK2,CPEB2,EGR3,CERCAM,TUBD1,ACSL4,TUBA1B,SYNCRIP,FLT1,ZBED3,MPP6,GCK,MMADHC,PPARGC1A,COPS8,GLI2,PARD3B,HLF,SCIN,KLHL23,SYTL4,ZNF827,TMOD2,PIK3R1,PURG,SNRK,SH3TC2,NCBP3,CSRNP3,SLC22A4,ZFP1,ZNF415,NSFL1C,SIK3,SLC44A1,BHLHB9,BEX4,RGMB,NR2C2,ZNF610,UBE2H,UGT8,NDRG4,SLC30A4,MFF,ADAMTS9,FAM198A" MicroRNA hsa-miR-499a-5p:TargetScan hsa-miR-499a-5p TargetScan 4.32E-26 2.42E-22 1.15E-25 1.06E-24 60 314 "KCTD16,OSBPL1A,LRCH2,APC,CDK13,MTMR3,PTBP2,CD38,CDH2,CFL2,QKI,C2CD2,CNTNAP2,GREB1,FAM131B,SCRN1,DNAL1,MYEF2,MTX3,DNM1L,EBF1,PLXNC1,EIF4G2,EIF5,EPB41L2,RRAGB,PCYOX1,CELF1,FUT9,FYN,CHL1,GLYR1,MSL1,LRRTM1,KCNN3,LIMS1,MEIS1,MMP16,NOVA1,CLDN11,PPP3CA,PRKAB2,PTPRG,PBRM1,FBXW7,SATB1,CSRNP3,SCN2B,FNIP1,HSPA4L,CHD9,FNDC3A,CDK19,CAMTA2,POGZ,LRRC8A,PRR18,REEP1,ANKS1B,EVI5" MicroRNA "GACTGTT,MIR-212:MSigDB" "GACTGTT,MIR-212:MSigDB" MSigDB 4.56E-26 2.55E-22 1.22E-25 1.12E-24 43 154 "OSBPL8,SEMA6A,PCDH10,PHF12,SEMA4G,TMEFF1,FUBP1,PTBP2,LRRFIP1,LARGE1,CFL2,ARHGAP32,ELMSAN1,POM121,DUSP9,PHF20L1,KMT5B,NCALD,OLFM1,MEX3B,FOXO3,CBX1,TJAP1,MMP16,HNRNPM,NFYA,NOVA1,MAPKAP1,RDX,PRRT2,GTDC1,RFX3,SEPHS1,BTBD7,SOX11,NMNAT2,MYCBP2,TRIM2,SIRT1,NEIL2,SGK3,NDRG4,FXR1" MicroRNA "GACTGTT,MIR-132:MSigDB" "GACTGTT,MIR-132:MSigDB" MSigDB 4.56E-26 2.55E-22 1.22E-25 1.12E-24 43 154 "OSBPL8,SEMA6A,PCDH10,PHF12,SEMA4G,TMEFF1,FUBP1,PTBP2,LRRFIP1,LARGE1,CFL2,ARHGAP32,ELMSAN1,POM121,DUSP9,PHF20L1,KMT5B,NCALD,OLFM1,MEX3B,FOXO3,CBX1,TJAP1,MMP16,HNRNPM,NFYA,NOVA1,MAPKAP1,RDX,PRRT2,GTDC1,RFX3,SEPHS1,BTBD7,SOX11,NMNAT2,MYCBP2,TRIM2,SIRT1,NEIL2,SGK3,NDRG4,FXR1" MicroRNA hsa-miR-132*:mirSVR_lowEffct hsa-miR-132*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-26 2.90E-22 1.38E-25 1.27E-24 70 427 "CC2D2A,SMIM17,APBA2,UPRT,CADPS,ASGR1,NUMB,BID,LDHD,SYNJ2,CACNA1B,P2RX6,UBE2L6,LHX2,CPNE6,NRXN3,RAB26,ENTPD4,GDA,CSNK1E,DCAF4,GUCD1,SGSM2,EXOG,CPEB2,SPEG,REEP2,FDFT1,NELFCD,WDR83,DOT1L,DISC1,MSTN,SPIN1,STARD3,FERMT2,GRIA2,RBPJ,KIF5A,LYPLAL1,MAT2A,ADAM11,KCTD6,VWA2,NUCB2,CDK18,LRP12,PCDHB17P,LRRN3,WBP1L,PIGG,RAP1GDS1,ZDHHC14,CCDC25,NEK11,FERMT1,ARFGAP1,MBD5,SOX11,SSTR1,SS18,STAU1,SYP,CUX2,RNF216P1,RGMB,AMACR,PPIL6,KCNE5,HPS4" MicroRNA hsa-miR-30b-3p:Functional MTI Functional MTI miRTarbase 5.34E-26 2.99E-22 1.42E-25 1.31E-24 89 667 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,RNPS1,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,CXXC4,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-223-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-26 3.05E-22 1.45E-25 1.33E-24 57 284 "ADD2,HACE1,TAOK1,PCDH10,ARRB1,ATP2A2,THSD7A,RUNX1T1,SEPT7,CFL2,IGLON5,PPP1R16B,DBT,JAKMIP2,SV2B,DMD,MBNL2,KATNAL1,FGF14,UBE2E3,MSANTD4,C15orf41,MMADHC,GLI2,CBX1,BVES,ZDHHC15,IGF1,IL6ST,KLHL23,KCNQ3,LIFR,SMAD9,CHIC1,MKLN1,MYO5A,NEXMIF,NCAM2,NELL2,GPR173,ZNF655,CCSER2,RGS4,FBXW7,SATB1,CSRNP3,FNIP1,ZHX3,NECAB1,ARHGEF9,PLCB1,ALG1,MGRN1,TRIM2,KCNK12,ADAMTS9,KAT6A" MicroRNA hsa-miR-185-5p:Functional MTI Functional MTI miRTarbase 5.64E-26 3.16E-22 1.50E-25 1.38E-24 64 359 "ADD2,CASKIN1,HACE1,TAOK1,PDZD4,SFMBT2,IGDCC4,BACH1,SCARB1,EPS15L1,ARHGEF6,ZNF385A,CSF1,CSNK1E,CNTNAP2,SLITRK5,TM9SF4,MATR3,IP6K1,SPATA2,ZC3H11A,CHRDL1,ABCC5,E2F6,CORO2B,FGFR1,AMOTL2,AFF2,CAMKK2,CELF1,DENND2A,SRCAP,TNRC6A,MSL3,GLUL,KAT7,SLC6A17,ZFYVE27,KITLG,ZC3H12B,NTRK3,GPR137C,PDE4A,PDPK1,PFKFB3,PKD1,PKM,PLCD1,ANKHD1,PRRT2,MORC4,HSD11B1L,MRAS,BTBD3,PKNOX2,SLC8A1,CCDC88A,IQSEC2,ARC,SMG6,TMEM9,SLC38A1,SIGLEC10,ITM2C" MicroRNA hsa-miR-30b-5p:Functional MTI Functional MTI miRTarbase 5.73E-26 3.21E-22 1.52E-25 1.40E-24 69 416 "AP2A1,TAOK1,SEMA6A,MARCH4,PCDH10,TNRC6C,USP37,STX16,ATP2A2,DPY19L3,ST3GAL5,TBPL1,BAG4,PREPL,CREM,CSF1,MATR3,SACS,FEM1B,CELSR3,MRO,MBNL2,ASB3,DCTN4,EPB41,SCML2,CHST15,ZNF589,CELF1,MSANTD4,HHIPL1,IP6K3,DBF4,TNRC6A,FERMT2,MIER3,ELOVL5,LIFR,SMAD1,LYPLAL1,MBNL1,REV3L,PBRM1,SETD5,ALG9,PCMTD2,SBF1,WDR37,BTBD7,CPEB4,TRERF1,BDP1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,ELOVL4,SYPL1,SLC35G2,NACC2,HEY1,RGMB,XPO1,MKRN3,ZBTB38,ZFAND5,PHTF2,ZDHHC20" MicroRNA hsa-miR-92b*:mirSVR_lowEffct hsa-miR-92b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.22E-26 3.48E-22 1.65E-25 1.52E-24 72 452 "ABHD6,ADD1,ADORA1,UNC5A,AK2,DOC2A,PITPNM2,AMPD3,PKP4,BCAS1,CPNE5,ADGRB2,DST,P2RX6,SYNGR3,EVI5L,WHRN,CABP1,NCOR2,ERC2,ARHGAP32,ARHGAP24,CHRDL1,ARRDC4,PHF20L1,MTSS1L,FCGR1A,FCGR1B,EVL,SEMA4D,DISC1,CLASRP,GSTT2,SLC2A6,ATXN2L,MIER3,GABARAPL2,SHISA6,FAM95B1,FXYD7,PFKFB3,TMIE,SLC25A23,PLTP,PILRA,FA2H,ELOVL2,ZNF493,RASGRF1,ZDHHC14,KIRREL1,PCMTD2,MCMBP,FAM192A,ATXN2,SHMT2,ARFGAP1,ZSWIM8,TSPYL2,ATP10B,SYP,MTCL1,CAMTA1,TBL1X,RPGRIP1L,SLC19A3,OBSL1,ZFPM2,GALNT17,CSMD1,RPRM,VIPR2" MicroRNA hsa-miR-185:PITA hsa-miR-185:PITA_TOP PITA 6.24E-26 3.49E-22 1.66E-25 1.53E-24 49 207 "ASIC1,PTCHD1,PCDH19,ATP1A3,CARMIL3,ADGRB1,THSD7A,DGKI,LHX2,ZNF385A,CSNK1G3,DGKB,C2CD2L,KLHL3,EIF1,RCAN2,AGAP3,CPLX1,TOX3,TNRC6A,KAT7,FAM222A,AGFG1,LRRTM1,KCNN3,MAP2,MAP4,MAT2A,MEIS1,MSI1,RTL5,NFIX,PCDH9,CCSER2,FAM184A,SETD5,LRFN5,SMARCC2,SNAP25,FAM219A,NMNAT2,HECW1,STAC2,TCF12,THRA,SSBP2,REEP1,SLC30A3,KAT6A" MicroRNA hsa-miR-653:PITA hsa-miR-653:PITA_TOP PITA 6.81E-26 3.81E-22 1.81E-25 1.66E-24 59 306 "PCDH19,FAM135A,CDC42BPA,CDK13,JAZF1,KRIT1,C1orf52,CDH2,ZFP28,CLOCK,SOCS5,RIMS2,SPOCK3,MBNL2,RGS17,SRRM1,TAOK3,SEC24B,IP6K2,AGAP2,ST6GALNAC3,SPIN1,CIT,SOX21,MBNL1,PPM1L,ZC3H12B,NOVA1,KCTD15,SCHIP1,KANSL1,PRKCB,SH3TC2,RDX,ZNF532,CHD9,PPP4R3A,SLC8A1,CCDC88A,TET1,RCOR3,FAM126B,SP4,SSTR1,LARP4,TCF4,RPGRIP1L,SIRT1,TPM1,UBTF,FLRT2,WIPF1,ZNF711,LYPD6,EMSY,CADM2,PRDM10,RGS7BP,MSRB3" MicroRNA hsa-miR-1914*:mirSVR_highEffct hsa-miR-1914*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.99E-26 3.91E-22 1.86E-25 1.71E-24 74 477 "SYS1,ADD1,ADD2,PTCHD1,BEND6,RTL9,ANK2,APLP1,BCAS1,RASL11B,TMEM108,CBS,SRSF11,LHX2,NRXN3,CNTFR,RCHY1,CLIP3,CSF1,UBXN2A,GAPVD1,SNAP91,DMD,LRRC17,CLVS1,FCGR1A,FCGRT,STRADA,ABLIM2,GABRA3,B4GALNT1,NEU3,PCDH17,MSL3,POLL,MSL1,KCNQ3,MEIS1,AFDN,MYO9A,NNAT,NOVA1,CNTN3,CYTL1,EPDR1,GDPD2,RIPOR1,MSANTD2,RDX,UBR7,KLHDC8A,YY1AP1,BAALC,KCNIP3,GALNT10,CCDC88A,KIF13A,SNRPN,BDP1,ATP10B,ZC4H2,SEPT8,CEP68,FAM208A,TBCEL,RPGRIP1L,PUM2,TNS2,ICAM5,STXBP4,VGF,SLC17A7,CASC15,JMJD1C" MicroRNA hsa-miR-1280:mirSVR_lowEffct hsa-miR-1280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.53E-26 4.21E-22 2.00E-25 1.84E-24 65 372 "SEMA7A,PPFIA3,AQP6,CDK10,RGS20,SLC2A11,ADAM15,KALRN,CH25H,ENTPD6,CDH2,ZMYM4,CCPG1,CHGB,PLAA,HECTD1,NCOR2,HDAC4,DGKG,DGCR5,SPOCK3,DNAH9,DTNB,DNM1L,ENPP6,RABEPK,IP6K2,MEGF10,GCK,ALDH1L1,PLCD4,ADAMTS13,RNFT2,FRMD3,USP51,CPT1C,C2CD4C,KIF5A,MAT2A,MATK,GIT1,ZNF92,NFIX,NTRK3,NUCB2,ZFYVE21,PCDHB17P,PRPSAP2,TMLHE,RTN1,PRCD,KIF21A,FAM214B,RBM26,STX1A,NUDT10,SYPL1,HIF3A,GALNT17,UBTF,LMF1,ZBTB14,EML6,MAP3K12,RNF146" MicroRNA hsa-miR-609:mirSVR_highEffct hsa-miR-609:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.13E-26 4.55E-22 2.15E-25 1.98E-24 71 442 "BEND6,LGR5,SEMA4G,ATP1A1,N4BP2L1,CARMIL3,ARHGEF7,MTMR2,CBFA2T2,LRBA,ZMYM4,NDST3,IGLON5,ABI3BP,CYBB,GPRASP1,ARHGAP32,DMD,DNM1L,AASS,DCTN4,GPHN,MRVI1,F5,CLVS1,SLC9B2,SPECC1,UFM1,USP21,FYB1,AHDC1,GGTA1P,GNAO1,FAM19A2,ZBTB49,GUCY1A1,RASSF8,TJAP1,MAN2A2,NF1,OGG1,PDPK1,MTRF1L,PKIA,HYDIN,DIRAS2,PTK2,TMEM145,SLC25A48,KCNIP1,ZNF568,SCP2,CCDC88A,SNRPN,TMCC1,PDZRN3,HECW1,ATP10B,MTCL1,DMXL2,FRYL,SIRT1,AKTIP,FAM124A,IL34,AMACR,GORASP1,VAV1,ZIC2,CASC15,ADAMTSL3" MicroRNA hsa-miR-186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-26 4.58E-22 2.17E-25 2.00E-24 72 454 "SYN3,XKR4,ZNF578,ATP1B3,LDHD,CACNA1A,KALRN,VXN,ZBED1,DIS3L,PLAA,ENTPD4,CRY2,SOCS5,PYGO1,DNAL1,SPATA2,KLHL3,DMD,SLC12A6,IRAK4,C8orf37,MRPL37,TLR7,TBC1D16,GTF2IRD2,FGF1,AMOTL2,IP6K2,ANKFY1,APOPT1,FUT9,TRAF3IP2,KIAA1841,SRCAP,FREM1,CRCP,RAB30,PTPRT,RNF165,HAS2,NKD1,SFXN5,GPR155,PPM1L,P2RX7,TMOD2,PIK3C2A,PLCL1,SMIM7,ZNF426,ZSCAN2,C12orf49,SCN2B,HSPA4L,SH3BP2,ATF7IP,ZHX3,SP2,POGZ,STAC2,KIAA0930,SATB2,GPRIN3,ZMAT3,PARD3,RUNDC3B,TOM1L2,ZNF708,ZNF70,MPPE1,GAN" MicroRNA hsa-miR-484:mirSVR_highEffct hsa-miR-484:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.53E-26 4.77E-22 2.26E-25 2.08E-24 82 579 "DGCR6,ACHE,ABHD6,C3orf14,LRFN2,PCDH19,CC2D2A,FAM135A,ARSE,CAST,MAGI1,SEC31B,CREM,ANKRD44,SNCAIP,CSF1,FAM169A,RIMS2,DCAF4,RIPOR2,RHOBTB1,SV2B,DPYSL2,SEMA3D,EIF4G2,STARD3NL,EPHB1,ETV1,FGF1,SPSB4,FHL1,POLK,AP4B1,ABLIM2,NEU3,COPS8,GRM2,RNF165,MAP4K5,PADI2,SCIN,IL6R,KCND1,KIT,MAP2,MBD1,MOV10,PTOV1,SLC11A2,RETREG1,SMIM7,GRAMD1C,SAMD9,APTX,BDNF-AS,TMEM260,PTPRE,ZMAT4,TRIM68,REV3L,GTDC1,GLDN,ABCA11P,SCP2,ZNF667,SNRPN,MYCBP2,KDM4C,ST5,TACR1,TBCEL,TBL1X,GPRIN3,CYB561A3,ENHO,TK2,NPL,LGI4,PROCA1,UPF3A,STOX2,PPP1R3F" MicroRNA hsa-miR-323b-5p:mirSVR_highEffct hsa-miR-323b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.38E-26 5.25E-22 2.49E-25 2.29E-24 72 455 "BEND6,SUGT1P4-STRA6LP-CCDC180,EIF4G3,ALDH7A1,ADAM23,MPDZ,CALB1,PTBP2,CAMK2B,METTL6,SYNGR3,TIGD7,RAB33A,SUMF2,SLC4A8,ZFYVE16,DDX46,WDR20,TMTC1,MBNL2,CALCRL,ERBB2,CEP78,GORAB,FGFR3,TPK1,TUBGCP4,TNRC6A,MUM1,INSM1,KCNJ16,LIMS1,ZNF667-AS1,MAP6,MARK1,MBNL1,MXI1,NDP,NTRK2,PRIMPOL,MINDY2,APTX,PIGG,PTPRE,MSANTD2,SLC25A36,SETD5,ALG9,ROBO1,NLGN1,CCDC88A,MBD5,LMBRD1,SNRPN,ERC1,DBNDD2,CLASP2,CEP68,NSFL1C,SYT1,FBXW11,ZEB1,TCF12,ARHGAP9,LRRC8A,AMACR,SPIRE1,ST7,UBE3B,KAT6A,FAM219B,NETO1" MicroRNA hsa-miR-1273h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.56E-26 5.35E-22 2.53E-25 2.33E-24 88 659 "XKR4,ADCY5,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-1825:PITA hsa-miR-1825:PITA_TOP PITA 9.64E-26 5.39E-22 2.55E-25 2.35E-24 46 182 "PCDH19,MARCH3,ADGRB1,BCL7A,CDH2,CFL2,CLCN3,CNR1,ARMC8,SLC35F1,PHC2,KLHL5,PAN3,REEP2,HPCAL4,FUT9,WASHC2A,PCDH17,SPIN1,PCLO,HLF,KIT,CHIC1,MITF,PDE1C,GPR85,ANKRD16,PPP2R5E,RIPOR1,FIGN,SCN8A,FNDC3A,FAM214B,CPEB4,SP2,SS18,KLHL7,PLCB1,ANKRD12,FBXW11,TCF4,TIAM1,UBTF,TMEM237,RTN4,JPH3" MicroRNA hsa-miR-6797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-25 5.60E-22 2.65E-25 2.44E-24 56 277 "ELFN2,ADCY5,RNF157,ADD2,CASKIN1,SORCS2,PHF12,PPFIA3,TTLL9,HAP1,TMEM184B,NCOR2,IP6K1,SPATA2,SEC16A,CHRDL1,MTSS1L,FGFR1,DOT1L,SRCAP,GLYR1,STARD3,ZBTB49,ZNF491,SHISA6,SOWAHA,NKD1,STMN1,NBL1,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,PKM,KCTD15,POLR2F,PPARA,MORC4,KIAA0895L,HES6,PEX26,TRIM67,CAMTA2,STX1A,ASTN2,GPRIN3,NACC2,WBP2,TUBB2A,MGAT5B,CLDND1,ZNF70,INTS3,PARP11,ACTR3B" MicroRNA hsa-miR-1468-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-25 5.74E-22 2.71E-25 2.50E-24 55 267 "SPOP,FAM135A,CDC42BPA,STX16,DST,CALM1,PTBP2,EVI5L,CFL2,QKI,DBN1,SPATA2,TMTC1,RCAN2,TAOK3,MED12L,MALT1,RAB30,FUT10,GRB10,ELOVL5,AGFG1,ZNF678,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,PSAT1,PPP2R5E,PRKACB,NWD1,KLHL11,SGK1,PEX26,SLC6A8,KIF13A,SPART,POGZ,DIP2A,ARC,SYPL1,DICER1,ZMAT3,TLR4,TUBB2A,RPL7L1,ZNF24,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-4316:mirSVR_highEffct hsa-miR-4316:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-25 5.90E-22 2.79E-25 2.57E-24 70 432 "KIAA1324,TAOK1,LRCH2,LGR5,ARHGDIA,BACH1,GYG2,CBR1,RAB28,GDA,SNCAIP,BOC,EARS2,TM9SF4,SLC29A4,E2F5,E2F6,TMEM35A,GPHN,PIPOX,EYA1,MRVI1,GTF2IRD2,NOP56,EFCAB2,KHDRBS3,ERAP1,PPARGC1A,PRUNE2,PCLO,KAT7,ATOH8,IRF8,GAREM2,RBPJ,SMAD9,MBD1,MBNL1,ZNF862,DNHD1,PCBP3,NTRK3,PFKFB2,ZNF655,MBOAT7,FSD1,STK32A,EML5,ZSCAN2,TUG1,FIGN,CCDC82,SETD5,CARF,ZNF568,FAM192A,ATXN2,FNDC3A,MAPKBP1,SNRPN,KDM4C,SSTR2,MTCL1,HIF3A,CYB561A3,PMS2CL,DCBLD1,RICTOR,ZNF45,EPM2A" MicroRNA hsa-miR-4649-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-25 6.10E-22 2.88E-25 2.65E-24 76 505 "ABCF1,AS3MT,XKR4,NDRG3,SLC24A4,TXNDC16,APAF1,AQP6,CDC14B,SFMBT2,ASPA,ZNF583,ZNF555,PTBP2,SLC16A4,NRXN3,AKAP5,SLC35F1,CRY2,IPCEF1,GREB1,SEC14L5,KIAA0408,LONRF1,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,E2F6,HEYL,RASA4,IRAK4,MRNIP,VPS26C,ZNF585B,ZNF589,ATP13A4,MSANTD4,GPR75,GLUL,ZNF638,BVES,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,BLOC1S2,SLC11A2,NUCB2,MTMR10,TMEM145,ZNF844,QDPR,GSTCD,SNX22,PTGR2,SALL1,SH3BP2,SLC2A5,SEPHS1,PEG10,CDK19,DDN,LHPP,ZSCAN29,FAM208A,PCDHA6,ARL10,SSBP2,TUBB2A,USP1,EVI5,MPPE1" MicroRNA hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 1.28E-25 7.14E-22 3.37E-25 3.10E-24 58 299 "NDRG3,GALNT16,ADCY6,OSBPL6,OGT,DPP10,NCOA1,BACH1,NOG,NUMBL,LHX2,RBM39,ERC2,HDAC4,RASSF2,MATR3,SCRN1,KIAA0753,GUCD1,DPYSL2,DTNA,KLHL5,EIF4G2,CERCAM,EPB41L2,ERBB4,FECH,ANKFY1,CELF1,PPARGC1A,GLUL,MIER3,LAMP2,MARK1,MPP2,GIT1,NFE2L2,NFYA,PAX6,GPR85,MAPK4,RIC8B,PBRM1,SBF1,HSPA4L,FAM102A,MYCBP2,CLSTN2,ANKRD12,SATB2,GPRIN3,GPR161,HEY1,NPL,RGMB,FLRT2,POLR3H,FXR1" MicroRNA hsa-miR-1184:PITA hsa-miR-1184:PITA_TOP PITA 1.43E-25 8.00E-22 3.77E-25 3.47E-24 52 239 "TAOK1,MAP4K3,NUMB,ADGRB3,CABP7,CAMK2G,TPP1,SH2B1,APPL1,MAML1,LYPD1,CHRDL1,TENM1,OLFM1,GABRB3,GNAO1,CIT,BACH2,AGFG1,KCNN3,NFIX,NPTX1,PDE4D,ENPP2,PIK3R1,PKIA,BCAS3,MTMR10,TMEM260,USP47,DUSP15,ZFHX4,SETD5,SCAF8,CPEB3,RCOR3,SOX11,HECW1,ERC1,PEG10,CAMTA1,TCF4,SATB2,TNS2,DICER1,TRIM9,ZFAND5,EMSY,SLC17A7,WNK3,PDSS2,HNRNPA3" MicroRNA hsa-miR-18b*:mirSVR_highEffct hsa-miR-18b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-25 8.41E-22 3.96E-25 3.65E-24 63 354 "BRAP,SUGT1P4-STRA6LP-CCDC180,SLC4A4,BBS2,PTBP2,CRLF1,TPP1,ARMC8,RCHY1,C2CD2,OSBPL3,PDE4DIP,GREB1,TMEM170A,SLC12A6,KRBA2,SNX29,VPS13B,LRRC17,SLC9B2,IP6K2,JKAMP,MEGF11,BRD8,RAB30,FERMT2,GPD2,GRIA2,MAT2A,NOVA1,SLC11A2,NUCB2,P2RY1,FAM218A,PRKACB,SNRK,BDNF-AS,ZSCAN32,PTPRG,ROBO2,SPIN3,SGK1,CNKSR2,SLC6A11,SLC9A5,SLC12A2,CXXC4,USP33,NFASC,CLSTN2,STAU1,TMEM150C,ANKRD12,TBCEL,ZFP90,PMS2CL,RASD2,AMACR,PLPPR2,FSTL5,DNALI1,NAV3,FAM198A" MicroRNA "CAGCTTT,MIR-320:MSigDB" "CAGCTTT,MIR-320:MSigDB" MSigDB 1.76E-25 9.85E-22 4.64E-25 4.27E-24 52 240 "UNC5A,PCDH19,OGT,LRCH2,CDK13,TMEM108,CDH2,FOXN3,QKI,PPP1R16B,HDAC4,DBN1,ARMCX2,RHOBTB1,KMT5B,PLXNC1,PAN3,NSRP1,MEX3B,FAM49B,PPARGC1A,NEGR1,SMAP1,ICA1,CDH20,HECTD2,MAT2A,MMP16,MN1,MXI1,PPM1B,PPP2R2C,TMEM255A,SEMA6D,FBXO11,BTBD3,DHX30,LMO3,TROVE2,POGZ,CAMTA1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TSC1,XPO1" MicroRNA hsa-let-7e-5p:Functional MTI Functional MTI miRTarbase 1.88E-25 1.05E-21 4.96E-25 4.56E-24 84 612 "FZD9,MTUS1,ZNF578,AMPD2,USP37,AQP6,IGDCC4,SLC2A11,BACH1,JAZF1,SPAG9,RUNX1T1,CLTC,CRY2,APPL1,DCAF8,MATR3,DNAL1,ELMSAN1,MTX3,DNAH9,SHANK1,DTNB,E2F6,EDN1,ANKRD46,SUGP2,EIF4G2,KATNAL1,TUBA1B,TRMO,TMEM107,PDLIM5,CELF1,DISC1,GATM,GLUL,POLL,FUT10,RABL2A,ATXN2L,IGF1,IL6R,KPNA5,THYN1,MYCN,NF1,NME4,SLC11A2,NUCB2,OPRL1,PSMA6,PTK2,QDPR,USP47,RDX,FIGN,C12orf49,SALL1,ATXN2,KIF27,CHD9,FNDC3A,DZIP1,SLC12A4,RCOR3,PEG10,MCF2L2,SYT1,TCF4,KIAA0930,SLC19A3,NSD1,MTMR14,CBX5,LRRC8A,TUBB2A,UBE2H,ZNF28,ZFAND5,SMARCAD1,FAM219B,JMJD1C,SPATA13" MicroRNA hsa-let-7a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-25 1.11E-21 5.23E-25 4.81E-24 86 639 "FZD9,MTUS1,ZNF578,USP35,AMPD2,AQP6,IGDCC4,ATP2A2,ALDH7A1,BACH1,BMPR1B,JAZF1,ZNF555,METTL6,CDC25B,CFL2,QKI,MAP4K4,CRY2,CS,PDE4DIP,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EGFR,EGR3,EIF4G2,TRMO,PDLIM5,CELF1,DISC1,GATM,NEU3,SESN1,TCERG1,GLUL,POLL,LILRB4,FUT10,CNTRL,RABL2A,HAS2,ATXN2L,HSF2,IL6R,KPNA5,PAXBP1,MEIS1,THYN1,MYO9A,NEFM,NME4,NPTX1,SLC11A2,NUCB2,OPRL1,PIK3R1,PKM,QDPR,USP47,RDX,FIGN,ATXN2,FNIP1,KIF27,COPZ1,SHMT2,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,DICER1,CBX5,TRIO,TUBB2A,SLC35A4,ZNF28,SMARCAD1,FAM13C,PHTF2" MicroRNA hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 2.10E-25 1.17E-21 5.51E-25 5.08E-24 61 334 "KCNH8,FMNL2,ADD2,PITPNM2,CDK13,NCOA1,NUMB,MTMR3,CAMK2G,CFL2,ARMC8,AKAP6,COL9A1,CLOCK,AKAP12,ANKRD44,DNAL1,CPEB2,EGR3,PLXNC1,ENPP6,CEP85L,APC2,EYA1,PCDH17,PPARGC1A,RNF165,RASSF8,MIER3,LSAMP,MAPT,MBNL1,MITF,NCAM2,OCRL,PDE4D,PIK3C2A,PPP2R2C,BCAS3,PIGG,FIGN,KLHL11,ROBO1,RORB,FBXW7,RXRA,SATB1,CSRNP3,CPEB3,BTBD7,CXXC4,FAM126B,ARHGAP26,LMO3,MMS19,CLASP1,DOK6,NR2C2,CLIP2,NDRG4,CADM2" MicroRNA hsa-miR-221-3p:Functional MTI Functional MTI miRTarbase 2.34E-25 1.31E-21 6.15E-25 5.66E-24 64 368 "TMEM132B,ADD1,BRAP,AP2A1,PHF12,APAF1,EIF4G3,ATP2A2,HECTD1,CNRIP1,RBM39,MTSS1L,ERBB4,FOXO3,EVL,SMC2,STAMBP,RNPS1,GLYR1,GRB10,FICD,ADAMTS6,KIT,STMN1,LIMS1,HECTD2,MAT2A,MBNL1,NFYA,PIK3R1,PKM,POLG,MAPK10,SLC25A36,RPL15,ZFP30,KIF16B,SEPHS1,ZFP1,TMCC1,SOX11,ERC1,PEG10,POGZ,ANKRD28,IQCE,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,TIAM1,ASXL3,RUNDC3B,TRPS1,TSN,UBC,CIAPIN1,NHSL1" MicroRNA hsa-miR-374a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-25 1.43E-21 6.72E-25 6.19E-24 56 282 "ABCF1,XKR4,ADD2,USP31,FAM135A,STX16,NRP2,ST3GAL5,CA8,SOCS6,ABCG2,HECTD1,RIPOR2,DBT,PITPNC1,TMTC1,MBNL2,ACSL4,DLC1,POLR1B,SEC23B,ANKFY1,ZBED3,GABRG2,TNRC6A,LUZP2,BACH2,MIER3,GABARAPL2,L1CAM,NF1,NFE2L2,OCRL,PDE4B,EPDR1,MAPK7,SETD5,BTBD3,BTBD7,CPEB4,RBM26,PBLD,STAU1,SYP,TACC1,ANKRD12,TRIM2,NSD1,SIK3,DICER1,NR2C2,TRPS1,UBE3A,ZFP37,SLC38A1,JMJD1C" MicroRNA hsa-miR-1274b:mirSVR_highEffct hsa-miR-1274b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-25 1.55E-21 7.26E-25 6.68E-24 72 463 "METAP1D,KLHL32,KIAA1211,TXNDC16,ADGRF5,CCDC146,UPRT,DOCK11,NRP2,MTMR2,CALB1,CPS1,CS,RIMS2,PDCD6IP,YAF2,PHF20L1,MBNL2,TUBD1,F8,ACSL4,ZNF589,ANKFY1,GALC,GATM,STON1,C1QL4,GRM8,RNF165,AP4S1,SOX21,ARHGAP36,AGBL5,CFAP126,SMAP1,C2orf72,NME9,GPR62,AFDN,NF1,SLC11A2,PDCD2,SLC10A4,FAM216A,MTRF1L,PURG,GRAMD1C,CNNM2,PTH1R,PTPRD,EML5,MARCH1,FIGN,RIC8B,RNASEL,ZNF532,CARF,STK32B,ATAT1,SUPT20H,COPZ1,ZNF667,SNRPN,ZBTB43,SPART,NXT2,ARHGEF9,SLC44A1,TIAM1,NPL,CELF4,FIP1L1" MicroRNA hsa-miR-142-3p.1:TargetScan hsa-miR-142-3p.1 TargetScan 3.24E-25 1.82E-21 8.52E-25 7.84E-24 55 273 "FMNL2,RNF157,MAP4K3,PHF12,APC,CASK,ARNTL,ATP2A2,BACH1,PROM1,ARHGEF2,CFL2,QKI,HECTD1,CLOCK,PUM1,NR1D2,CPEB2,PAN3,LRRC17,ANKFY1,AFF2,GHR,DIDO1,KAT7,BACH2,IL6ST,ITPKB,MAP2,MARK3,LRP1B,MEF2C,MEIS1,AFF1,MYO5A,P2RY1,GPR137C,PDE4B,PPP3CA,MARCH1,ATXN2,ATXN7,FNDC3A,DHX30,BTBD7,ATF7IP,ERC1,LMO3,PLCB1,PCDHB15,GPRIN3,MTCH1,RICTOR,JMJD1C,NHSL1" MicroRNA hsa-miR-3689a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-25 1.82E-21 8.54E-25 7.86E-24 87 657 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-3689c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-25 1.82E-21 8.54E-25 7.86E-24 87 657 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-3689b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-25 1.82E-21 8.54E-25 7.86E-24 87 657 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA "ACTGCCT,MIR-34B:MSigDB" "ACTGCCT,MIR-34B:MSigDB" MSigDB 3.30E-25 1.84E-21 8.64E-25 7.96E-24 48 205 "TMCC3,ADORA2A,KCTD16,TAOK1,ALCAM,ANK2,ATP1B3,JAZF1,WASF1,EVI5L,MAGI1,CACNA2D2,FOXN3,MYRIP,PPP6R2,ELMSAN1,CELSR3,TENM1,PLEKHA1,SUCO,FAM49B,IQGAP2,ATXN2L,SHISA6,ICA1,INSM1,MAN2A2,MAT2A,MITF,MSI1,NFIX,CNOT4,NPTX1,OCRL,MAPK4,PTPRG,RDX,RIC8B,CPEB3,FAM219A,MYCBP2,ANKRD12,MTCL1,TRIM2,TCF12,RIMBP2,NAV3,NETO1" MicroRNA hsa-miR-31*:mirSVR_highEffct hsa-miR-31*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.32E-25 1.86E-21 8.71E-25 8.02E-24 63 359 "RALGAPA1,AS3MT,KIAA1324,VAT1L,LINC00173,MARK4,RIPK1,BACH1,CA8,CA12,KALRN,RUNX1T1,SYNGR3,LRRFIP1,CHN2,ARHGEF10,PLXNA4,PNPLA8,KIF26A,DAPK1,USP3,DLC1,FCGR3A,TCERG1,PCLO,FAM19A2,MAP4K5,GPR62,SMAD1,TM6SF1,LRP1B,MN1,MOV10,MSR1,NFE2L2,GPR137C,GNG2,PLCL1,EPB41L4B,MASP1,SNRK,GTDC1,ADAL,ZNF568,CCDC112,CSRNP3,FNIP1,SH3BGR,SYBU,SEC31A,SLC6A11,NAPB,DBNDD2,SSPO,VPS13A,PLCB1,COBL,TCEA1,UBE2H,UGT8,PCDH20,ZNF711,EMSY" MicroRNA hsa-miR-335:PITA hsa-miR-335:PITA_TOP PITA 3.37E-25 1.89E-21 8.83E-25 8.13E-24 46 187 "ELFN2,CCDC85A,PCDH19,SLC4A4,OSBPL3,FAM131B,DOCK4,LONRF1,SPOCK2,FAM107B,ABCC5,ERBB4,KDM2B,RAB40B,KAT7,ZHX1,HMGCR,ITPKB,MAP2,PCDH9,GNG2,ZDHHC8,STRN3,EPB41L4B,MAPK10,TMEM260,ZNF532,SALL1,SCN2B,PPM1E,CPEB4,ZSWIM8,NMNAT2,KDM4C,ZC4H2,SYN2,CAMTA1,TCF4,TIAM1,TSC1,RPRM,UBE2H,POLR3H,EVI5,RGS7BP,HNRNPA3" MicroRNA hsa-miR-508-5p:PITA hsa-miR-508-5p:PITA_TOP PITA 3.40E-25 1.90E-21 8.89E-25 8.19E-24 47 196 "BCL7A,KSR1,SYNJ1,FOXN3,RAB33A,SLC35F1,AKAP12,OSBPL3,HDAC4,TMCC2,DMD,EGR3,CELF1,FUT9,TNRC6A,MAP4K5,IGF1,INSM1,KCND1,KIT,KITLG,MYO6,NEXMIF,NEFH,SLC11A2,NTRK2,PCSK1,PDE4B,MINDY2,PTK2,TMEM260,SH3TC2,FIGN,FBXW7,RTN1,CPEB3,SOX11,TTBK2,ANKRD28,TBL1X,TCF4,SATB2,NSD1,FRYL,RELL2,DOK6,ZNF189" MicroRNA hsa-miR-27a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-25 2.05E-21 9.57E-25 8.81E-24 69 429 "ADD1,FZD9,TAOK1,SEMA6A,SEMA7A,APBB2,APC,ARNTL,ZBTB10,RNF182,DPY19L3,SOCS6,CNN3,RGS6,LONRF1,LIN54,ELMO1,C2CD2L,SEC16A,NR1D2,PHC2,FEM1B,EGFR,KMT5B,EIF5,DNAJC27,GTF2IRD2,AMOTL2,SUCO,FAM49B,CELF1,OGA,ZNF638,GPT2,MIER3,HMGCR,IGF1,FAM69A,SLC6A17,LAMP2,LIFR,MKLN1,MYO9A,MYT1,NF1,NFE2L2,RETREG2,BDNF-AS,ALG9,FBXW7,RXRA,SEMA6D,COPZ1,FNDC3A,SLC6A8,CPEB4,ZFP1,SP4,ERC1,PEG10,TROVE2,MPRIP,STAU1,NSD1,FRYL,ZNF106,TTC3,AP3B2,SPATA13" MicroRNA hsa-miR-297:PITA hsa-miR-297:PITA_TOP PITA 3.81E-25 2.13E-21 9.98E-25 9.19E-24 51 234 "OSBPL8,MAP4K3,NCOA1,EIF4G3,WASF1,LRBA,ERC2,PLCXD3,SNAP91,MBNL2,EGR3,SRRM1,SUCO,PSD2,GABRB3,SESN1,TCERG1,GRIA2,INSM1,XRRA1,NRCAM,STRN3,LRP12,GDPD1,QRICH1,CLIP1,SCN8A,HSPA4L,FHOD3,R3HDM2,CCDC88A,CAMTA2,NKAIN2,CAMTA1,TCF4,TCF12,SYNE1,CSMD1,KAT6B,TPM1,TRPS1,SSBP2,VLDLR,XRCC4,ZIC2,ZBTB38,ZFAND5,EMSY,CADM2,EVI5,KCNAB1" MicroRNA hsa-miR-1249-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.92E-25 2.19E-21 1.02E-24 9.43E-24 55 274 "ELFN2,ADCY5,RNF157,ADD2,CASKIN1,SORCS2,PHF12,PPFIA3,TTLL9,HAP1,TMEM184B,NCOR2,IP6K1,SPATA2,SEC16A,CHRDL1,MTSS1L,FGFR1,DOT1L,SRCAP,GLYR1,STARD3,ZBTB49,ZNF491,SHISA6,SOWAHA,NKD1,STMN1,NBL1,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,PKM,POLR2F,PPARA,MORC4,KIAA0895L,HES6,PEX26,TRIM67,CAMTA2,STX1A,ASTN2,GPRIN3,NACC2,WBP2,TUBB2A,MGAT5B,CLDND1,ZNF70,INTS3,PARP11,ACTR3B" MicroRNA hsa-miR-106a-5p:Functional MTI Functional MTI miRTarbase 4.18E-25 2.34E-21 1.09E-24 1.01E-23 91 714 "FMNL2,FZD9,SORCS2,ZNF578,MARCH4,SEMA7A,APC,ATP1B3,RNF182,LDHD,MTMR3,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,ENTPD4,SOCS5,UBXN2A,DCAF8,DNAL1,YTHDC1,FBXL5,SLC12A6,DPYSL2,DNAJB6,HIPK3,FEM1B,KMT5B,EIF4G2,IRAK4,CERCAM,TLR7,KATNAL1,ACSL4,GTF2IRD2,POLR1B,SUCO,TPK1,TRAF3IP2,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,CBX1,LUZP2,FUT10,FICD,HAS2,KCNB1,GPR155,NBL1,CNOT4,PDPK1,PFKFB2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,CEP97,ZNF532,CYB561D1,ATAT1,TMEM200C,HSPA4L,FAM126B,SP2,SP4,STAC2,GPRIN3,ZMAT3,NACC2,CBX5,PARD3,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-3606-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-25 2.41E-21 1.13E-24 1.04E-23 46 188 "FZD9,SPOP,ZNF582,SLC2A11,BACH1,ZNF555,HDAC4,EDN3,ENPP6,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,CCSER2,KANSL1,PRKACB,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,CEP68,DICER1,TRPS1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-643:PITA hsa-miR-643:PITA_TOP PITA 4.35E-25 2.43E-21 1.13E-24 1.04E-23 50 225 "CCDC85A,HECW2,LCORL,GAS7,ARNTL,USP6,NUMBL,RAB33A,CNR1,IGDCC3,PHACTR3,GAPVD1,LONRF1,DDX46,USP3,DPYSL2,EBF1,HIPK3,YAF2,MBNL2,ERBB4,CLVS1,SPIN1,RAB30,FAM19A2,PSIP1,NEGR1,MAP2,MEIS1,CLDN11,LRP12,SCHIP1,DIRAS2,TTC13,RORB,FNIP1,WDR47,TET1,NEK4,FAM208A,SATB2,TRIM2,TCF12,DOCK9,AP4E1,ZNF106,SLC44A1,KAT6B,SLC38A1,MSRB3" MicroRNA "AACTGGA,MIR-145:MSigDB" "AACTGGA,MIR-145:MSigDB" MSigDB 4.35E-25 2.43E-21 1.13E-24 1.04E-23 50 225 "ABR,SEMA6A,SPOP,FAM135A,EPB41L5,ZBTB10,SLC4A4,MYRF,CFL2,QKI,MAP4K4,CABP1,TBPL1,AKAP12,ARHGAP24,TM9SF4,ELMO1,ZC3H11A,MTX3,DPYSL2,VPS13B,GPHN,ACSL4,SPSB4,AMOTL2,AFF2,ABLIM2,GGT7,KDM2B,C1QL4,BACH2,GABARAPL2,BLOC1S2,MYO5A,XRN1,PPP3CA,REV3L,RGS3,CCDC25,ATXN2,ZFP2,KIF21A,FNDC3A,CPEB4,SOX11,ZNF423,ARHGAP26,PRRC2C,ANKRD28,TRIM2" MicroRNA hsa-miR-6780a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-25 2.50E-21 1.17E-24 1.08E-23 87 660 "XKR4,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,ISPD,SLC16A4,LONRF2,CDR1,SUMF2,CRY2,NCOR2,UBXN2A,USP6NL,MYADM,GAPVD1,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,AGBL5,ZNF491,IGF1,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PFKFB3,KANSL1,MTMR10,QDPR,CEP97,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,MYO18A,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,TMEM63C" MicroRNA hsa-miR-219-5p:mirSVR_highEffct hsa-miR-219-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.53E-25 2.54E-21 1.18E-24 1.09E-23 73 479 "KCNH8,ADD2,RTL9,LGR5,SEMA4G,PLA2G4C,NCOA1,RNF182,N4BP2L1,ADGRB3,KALRN,LRBA,AKAP6,COL9A1,TOGARAM2,CNRIP1,GREB1,DDX46,RHOBTB1,CDON,TOM1,KLHL5,EGR3,PAN3,EYA1,ZSCAN30,SLC9B2,HPCAL4,FLT1,TUBGCP4,PPARGC1A,TTBK1,MIER3,KTN1,PACRG,MYO7A,NME4,DNHD1,OCRL,ZNF827,PURG,PDZRN4,TRHDE,ING3,VPS13C,SNRK,STK32A,PTPRG,MORC4,SETD5,RORB,ELP2,MCMBP,SATB1,SCN7A,HSPA4L,FERMT1,ANKRD6,TET1,SP4,MCF2L2,NUDT10,SYT5,MMS19,ADGRL3,SATB2,TIAM1,TPM1,UBE3A,PLEKHH2,VLDLR,NDRG4,SLC30A4" MicroRNA hsa-miR-558:PITA hsa-miR-558:PITA_TOP PITA 4.97E-25 2.78E-21 1.30E-24 1.19E-23 41 146 "ELFN2,PCDH19,TBC1D14,PDZD4,MTMR3,CABP7,KALRN,HECTD1,DBN1,C2CD2L,ALKBH8,SNAP91,DPYSL2,ABCC5,AGAP2,FLNC,SESN1,GRIN2D,KAT7,ATXN2L,SYNPO,NEGR1,MEIS1,MXI1,MYT1,PDE4B,USP47,DPF2,KIF21A,SEPHS1,SLC8A1,NKAIN2,ANKRD28,SATB2,RPGRIP1L,ZFPM2,ZNF106,RIMBP2,ZFAND5,KAT6A,SENP7" MicroRNA "GTTTGTT,MIR-495:MSigDB" "GTTTGTT,MIR-495:MSigDB" MSigDB 5.79E-25 3.24E-21 1.51E-24 1.39E-23 51 236 "OGT,NCOA1,ATP2B2,ADGRB3,CAMK2G,RUNX1T1,CBFA2T2,SEPT7,LARGE1,SRSF11,LHX2,CNR1,ARMC8,CSNK1E,RIMS4,MBNL2,RGS17,BAIAP2,FOXO3,AFF2,CELF1,TNRC6A,AGBL5,IGF1,MARK3,PDE4D,EPB41L4B,PPP3CA,PRRT2,RORB,SEMA6D,SATB1,SCN8A,SGK1,CPEB3,FAM219A,SP4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RASD2,UBE3A,RICTOR,USP32P2,EMSY,ST8SIA2,CPNE4" MicroRNA hsa-miR-150-5p:TargetScan hsa-miR-150-5p TargetScan 5.95E-25 3.33E-21 1.55E-24 1.43E-23 54 266 "METAP1D,PKP4,APC,CDK13,N4BP2L1,DST,CACNA1G,PTBP2,CAMK2G,CAST,CCNT1,DGKI,CFL2,LETMD1,SEC31B,RIMS2,ELMSAN1,KLHL3,NR1D2,PLXNC1,DENND4A,MRVI1,NBEA,MPP6,GABRG2,GPR75,NXPH3,IGFBPL1,NEGR1,KCNB1,KCNN3,PIK3AP1,MMP16,NEFM,NOVA2,NLGN3,PLXNB1,CNNM2,PIGG,PTPRB,PRRT2,FIGN,CYB561D1,RORB,KCNIP1,SBF1,SCP2,CPEB4,PEG10,NFASC,FBXW11,MAP3K12,FAM47E,GAN" MicroRNA hsa-miR-339-3p:mirSVR_lowEffct hsa-miR-339-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.36E-25 3.56E-21 1.65E-24 1.52E-23 65 386 "DGCR6,UNC5A,PCDH19,AMPD3,SUGT1P4-STRA6LP-CCDC180,CPNE5,SLC2A11,N4BP2L1,ADAM15,CA4,THSD7A,PTBP2,CBFA2T2,TAOK2,ARHGAP22,SULT4A1,PICK1,LETMD1,RTTN,CREM,SNCAIP,CST3,PITPNM3,USP3,TOM1,DUSP9,EPHB1,RACK1,SLC37A3,RUNDC3A,MSL3,ZNF638,CLASRP,FAM222A,VSIG4,ITGA7,PFKFB3,PPP1R1A,DIRAS2,NDUFS7,WBP1L,TMEM260,FAM66C,RBBP8,ERI2,RGS12,ZNF532,FAM192A,SLC14A1,ARFGAP1,TTC17,ZNF423,PBLD,AGTPBP1,MGRN1,PCDHGA11,GPRIN3,RIMBP2,TRIO,CLEC2L,TOM1L2,VIPR2,CLIP2,URM1,FIP1L1" MicroRNA hsa-miR-455-3p.1:TargetScan hsa-miR-455-3p.1 TargetScan 6.39E-25 3.58E-21 1.66E-24 1.53E-23 56 287 "FMNL2,ADORA2A,PWWP2A,OSBPL8,LTBP4,PPFIA3,DYNLL1,KALRN,RUNX1T1,CCNH,CACNA2D2,LHX2,CLTC,ARMC8,ARHGAP32,EARS2,CHRDL1,CDON,DRP2,PHC2,HEYL,CELSR3,APH1A,ETV1,PTK2B,RAB30,GPD2,GRB10,HAS2,GABARAPL2,RBPJ,KCND1,KIF5A,MSANTD3-TMEFF1,MPP2,SAMD5,MYO6,PAX6,PIK3R1,PPP2R5E,PRKAB2,GAL3ST4,CYB561D1,ROBO1,SALL1,SCN2B,ARX,CDK19,DIP2A,PUM2,FRYL,RUSC1,RICTOR,INTS3,RTN4,CPNE4" MicroRNA hsa-miR-130a-3p:Functional MTI Functional MTI miRTarbase 6.75E-25 3.78E-21 1.76E-24 1.62E-23 66 398 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,CSF1,DAPK1,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,PPARGC1A,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PPARA,PIGG,PTPRG,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MAP3K12,MFF,WNK3,FXR1" MicroRNA hsa-miR-196b-5p:TargetScan hsa-miR-196b-5p TargetScan 6.86E-25 3.84E-21 1.78E-24 1.64E-23 55 277 "BRAP,PCDH19,ARHGAP20,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,BACH1,MTMR3,GYG2,CALM1,FAM19A5,PCYT1B,LETMD1,ENTPD4,PPP1R16B,PPP6R2,HDAC9,EBF1,RASGRP1,MBNL2,RGS17,LRRC17,FGF14,GALC,C15orf41,PRUNE2,PRDM5,FRMD5,DDX19B,HLF,IGF1,RBPJ,KLHL23,LRP1B,NME4,PFKFB3,SCHIP1,PTPRG,RDX,ERI2,GTDC1,ATP8B4,FNIP1,CPEB3,PEG10,LARP4,DIP2A,RPGRIP1L,DOK6,NR2C2,RICTOR,GAN" MicroRNA hsa-miR-196a-5p:TargetScan hsa-miR-196a-5p TargetScan 6.86E-25 3.84E-21 1.78E-24 1.64E-23 55 277 "BRAP,PCDH19,ARHGAP20,LCORL,MAP4K3,GAS7,IGDCC4,CASK,CHRD,BACH1,MTMR3,GYG2,CALM1,FAM19A5,PCYT1B,LETMD1,ENTPD4,PPP1R16B,PPP6R2,HDAC9,EBF1,RASGRP1,MBNL2,RGS17,LRRC17,FGF14,GALC,C15orf41,PRUNE2,PRDM5,FRMD5,DDX19B,HLF,IGF1,RBPJ,KLHL23,LRP1B,NME4,PFKFB3,SCHIP1,PTPRG,RDX,ERI2,GTDC1,ATP8B4,FNIP1,CPEB3,PEG10,LARP4,DIP2A,RPGRIP1L,DOK6,NR2C2,RICTOR,GAN" MicroRNA hsa-miR-484:Functional MTI Functional MTI miRTarbase 7.28E-25 4.07E-21 1.89E-24 1.74E-23 103 891 "ABCF1,AMPD2,APLP1,ARHGDIA,ATP1A1,ATP2A2,DST,SPAG9,CBR1,CERS5,LONRF2,TAOK2,CLTC,TMEM184B,AKAP7,PREPL,ENTPD4,RBM39,SH2B1,RNF14,NCOR1,ELMSAN1,POM121,SEC16A,EXOG,FIS1,SUGP2,EIF4G2,TNK2,DCTN4,TUBA1B,MED12L,SUCO,SEMA4D,TUBGCP4,SRCAP,AHDC1,TNRC6A,MSL3,GLUL,PRRC2B,ZBTB45,IPO5,STMN1,GPR155,MAN2A2,MAP4,MAT2A,MEIS1,MPP2,GIT1,MYO5A,HNRNPM,NEK1,NME4,SLC11A2,OCRL,TMOD2,PKD1,ZFYVE21,PKM,NLE1,EXOSC10,MBOAT7,POLG,C12orf49,ELP2,PTGR2,CASC3,PUF60,FUZ,NUBPL,DHX30,KANSL3,SLC6A8,SEPHS1,ATF7IP,ANKRD36,ZSWIM8,PEG10,ZNF621,DIP2A,NSFL1C,JMJD6,SUPT5H,SYNE2,PDLIM2,ZEB1,CBX5,DCBLD1,HSPBP1,TUBB2A,SGK3,UBTF,CCDC136,TBC1D15,KLC2,POLR3H,SPIRE1,UPF3A,SLC38A1,HNRNPA3,NHSL1" MicroRNA hsa-miR-150:PITA hsa-miR-150:PITA_TOP PITA 8.69E-25 4.86E-21 2.25E-24 2.08E-23 47 200 "APC,CACNA1G,CAST,ZMYM4,RIMS2,ELMSAN1,C2CD2L,KLHL3,POM121,NR1D2,KMT5B,PLXNC1,KCTD3,EIF5,EPB41,NBEA,GABRG2,PPARGC1A,TNRC6A,RNF165,NEGR1,KCNN3,IPO5,NFIX,NRCAM,NLGN3,SEMA5B,MAPK9,PTCH1,PTPRB,PRRT2,SETD5,RORB,PPM1E,CPEB4,TMCC1,SOX11,ERC1,FBXW11,ZEB1,TRPS1,ZNF189,MAP3K12,HRASLS,KAT6A,PHTF2,RNF146" MicroRNA hsa-miR-4768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.92E-25 4.99E-21 2.31E-24 2.13E-23 86 653 "NDRG3,SLC24A4,TXNDC16,SMIM17,TRMT9B,APAF1,AQP6,CDC14B,SFMBT2,ARHGDIA,ASPA,ZNF583,ZNF555,PTBP2,ISPD,CBS,MTMR7,SLC16A4,CCPG1,NDST3,NRXN3,SLC35F1,SUSD5,IPCEF1,PITPNM3,CTH,RUBCN,USP6NL,PYGO1,RASSF2,LONRF1,TMEM170A,ELMSAN1,SLC29A4,HEYL,ZNF549,VPS26C,ZNF585B,ZNF589,ATP13A4,MSANTD4,MTHFD2,GPR75,GLUL,ZNF638,LUZP2,LILRA2,ZBTB49,BVES,AGBL5,KCNH2,KCNJ5,KLHL23,STMN1,SMAD9,CHST6,PPM1L,MMP17,MPP2,MXI1,SFR1,ZNF713,PLEC,KANSL1,MTMR10,ZNF844,QDPR,CEP97,ALG9,GSTCD,SNX22,HSD11B1L,PREX2,SLC2A5,CDK19,NEK4,FAM208A,SLC19A3,PCDHA6,TMEM9,SSBP2,ZNF610,RPRM,TBC1D15,DNALI1,MPPE1" MicroRNA hsa-miR-654-3p:PITA hsa-miR-654-3p:PITA_TOP PITA 9.32E-25 5.21E-21 2.42E-24 2.22E-23 49 219 "TMEM132B,ZNF608,OSBPL8,TAOK1,BEGAIN,ATP2A2,NRP2,SYNJ1,JAZF1,CACNA1I,QKI,RIMS2,ARHGAP24,ELMO1,MTX3,SEMA3D,CELSR3,EGR3,FGF14,ANKFY1,AFF2,CPLX2,PPARGC1A,PCLO,PSIP1,ZIC5,KCND2,GIT1,NEFM,NPTX1,PCDH18,QRICH1,RDX,HUNK,SCN8A,CPEB3,SLC6A8,CPEB4,RCOR3,FAM126B,TBL1X,SATB2,NR2C2,KCNE5,REEP1,CADM2,PDSS2,HNRNPA3,FXR1" MicroRNA hsa-miR-665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-24 5.78E-21 2.68E-24 2.46E-23 92 737 "ABCF1,AS3MT,NDRG3,SLC24A4,HACE1,TXNDC16,TRMT9B,APAF1,AQP6,CDC14B,SFMBT2,ZNF583,ZNF555,CBS,MTMR7,SLC16A4,EVI5L,CCPG1,SOCS6,NDST3,NRXN3,SUMF2,SLC35F1,IPCEF1,PYGO1,MYADM,TMEM170A,ELMSAN1,SGSM2,MTX3,DNAH9,SLC29A4,HEYL,TMTC1,MRO,RASA4,IRAK4,MRNIP,VPS26C,ANKMY1,ZNF585B,ZNF589,FOXO3,ATP13A4,MSANTD4,SESN1,CRCP,GPR75,GLUL,ZNF638,GNG4,BVES,AGBL5,IGF1,KLHL23,SMAD9,MATN3,SHC3,PPM1L,MPP2,SLC11A2,PPP2R2B,NCR3LG1,MTMR10,TMEM145,QDPR,CEP97,MSANTD2,RGS12,GSTCD,PTGR2,NCBP3,SH3BP2,SLC2A5,PKNOX2,SEPHS1,ATF7IP,CDK19,MCF2L2,LHPP,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ARL10,TMEM9,USP1,LAT2,ZNF17,INTS3,DNALI1,EVI5" MicroRNA hsa-miR-23a*:mirSVR_highEffct hsa-miR-23a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-24 5.83E-21 2.70E-24 2.49E-23 66 401 "PLEKHH1,C1QTNF3,MARCH3,RASL11B,CCAR2,BACH1,LINC00847,KSR1,CA4,ARHGEF2,IGLON5,CNTN1,SMARCAL1,CLIP3,CSF2RA,ERC2,UBXN2A,TM9SF4,KIAA0753,SGSM2,EXOG,ECM2,FGF11,PSD2,NELFCD,CGREF1,OGA,HRASLS5,DISC1,PPARGC1A,WDFY3-AS2,GPER1,AP4S1,PADI2,FRMD5,HNF4G,INSM1,MBD1,MBNL1,MEIS1,KCTD6,SCAMP5,NTRK3,PIK3C2A,SLC26A11,WDR25,FAT4,KHDRBS2,CCDC102B,KCNIP3,KCNIP1,ZNF430,SLC9A5,SLC11A1,ATF7IP,RCOR3,PDZRN3,SP2,JMJD6,SYN1,ENHO,TLR4,ERCC6L2,ZNF225,SLC17A7,WNK3" MicroRNA hsa-miR-125a-3p:PITA hsa-miR-125a-3p:PITA_TOP PITA 1.07E-24 5.98E-21 2.77E-24 2.55E-23 44 174 "KLHL13,SYNJ1,LDLRAD4,LDB2,DGKI,CFL2,SIPA1L1,RIMS4,ARHGAP24,DGKG,DPYSL2,EVL,FYN,MEGF11,GATM,PRRC2B,PRDM5,ELOVL5,KIF2A,MBD1,LRP1B,MEF2C,MITF,NF1,CNOT4,PCDH8,CCSER2,PKIA,MSANTD2,RGS4,SGK1,NLGN1,FAM214B,SLC8A1,LMO3,ZC3H4,EXOC7,SZT2,MTMR14,TRPS1,FAM155A,MAP3K12,CADM2,FXR1" MicroRNA hsa-miR-605:PITA hsa-miR-605:PITA_TOP PITA 1.10E-24 6.14E-21 2.84E-24 2.61E-23 56 290 "ADRB2,TAOK1,FAM135A,OGT,LRCH2,CHRD,CACNA1A,RUNX1T1,LRBA,CDH2,MAGI1,CFL2,B4GALT6,CLOCK,SH2B1,LRIG1,CSNK1G3,SLITRK5,TCAF1,DGKG,MTX3,NR1D2,MBNL2,EGR3,TMEM132E,PAN3,MSTN,PCDH17,LPAR4,ADAMTS6,NKD1,NEXMIF,MYT1,ZC3H12B,OLA1,LRP12,PTCH1,PTX3,SH3TC2,ST6GALNAC6,NCBP3,CSRNP3,TRIM67,FAM126B,POGZ,ZC4H2,ANKRD12,ADGRL3,TCF4,CUX2,SLC44A1,KAT6B,EIF4ENIF1,UBE3A,FLRT2,RNF146" MicroRNA hsa-miR-765:PITA hsa-miR-765:PITA_TOP PITA 1.12E-24 6.28E-21 2.90E-24 2.67E-23 45 183 "ASIC1,UNC5A,SEMA6A,SYNJ1,CACNA1G,CAMK2G,RUNX1T1,DCLK1,FOXN3,CNTFR,AKAP5,ZNF385A,GAPVD1,IST1,CHRDL1,NRN1,TAOK3,AFF2,TMEM107,C15orf41,CPLX1,AHDC1,GFRA2,BACH2,MAT2A,MEIS2,NFIX,NTRK3,KCTD15,LRRN3,MAPK10,CYB561D1,ATXN2,FAM102A,SLC11A1,SMARCA4,SOX11,SP2,SEPT3,NSFL1C,SYN1,TCF4,THRA,LRRC8A,ZIC2" MicroRNA hsa-miR-409-5p:mirSVR_highEffct hsa-miR-409-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-24 6.67E-21 3.08E-24 2.84E-23 55 280 "KCTD16,CCDC146,LGR5,DPY19L3,TIGD7,SRSF11,DGCR9,ARHGEF6,LETMD1,CST3,PUM1,ZFYVE16,DGKG,SPOCK3,DNM1L,FSD1L,KMT5B,NCALD,RRAGB,STAU2,ABLIM2,FREM1,PPARGC1A,WDFY3-AS2,SERP2,METTL21A,PURG,MINDY2,HYDIN,RELN,ANKHD1,RFX2,NEK11,ATP8B4,ZFP30,FAM214B,KDM4D,SLC12A2,SMARCD3,C12orf76,CAMTA1,SATB2,PCDHB4,FRYL,SLC44A1,NR2E1,TRO,PLEKHH2,TBC1D15,KLC2,ZIC1,FTSJ1,KCNAB1,FZD3,NETO2" MicroRNA hsa-miR-7160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-24 7.07E-21 3.27E-24 3.01E-23 73 487 "ABCF1,AS3MT,NDRG3,TXNDC16,APAF1,AQP6,CDC14B,SFMBT2,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,SUMF2,SLC35F1,IPCEF1,KIAA0408,IST1,TMEM170A,ELMSAN1,SV2B,SGSM2,DNAH9,SLC29A4,HEYL,TMTC1,RASA4,IRAK4,EIF1,VPS26C,ZNF585B,ZNF589,ATP13A4,MSANTD4,CRCP,GPR75,GLUL,ZNF638,BVES,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,SLC11A2,EPB41L4B,MTMR10,TMEM145,QDPR,ALG9,GSTCD,PTGR2,SH3BP2,SLC2A5,PEX26,EPN2,SEPHS1,CDK19,MCF2L2,LHPP,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ARL10,SSBP2,USP1,EVI5,ITM2C,MPPE1,ZDHHC20" MicroRNA hsa-miR-217:TargetScan hsa-miR-217 TargetScan 1.27E-24 7.08E-21 3.27E-24 3.01E-23 59 323 "RNF150,BEND6,INTS2,KCTD16,DST,DLGAP2,CHN2,QKI,CLOCK,RBM39,PLXNA4,RIMS2,DOCK4,ARHGAP32,LIN54,MYEF2,CHRDL1,PDCD6IP,RCAN1,EDIL3,HIPK3,FSD1L,FOXO3,RAPGEF6,PCDH17,PPARGC1A,PARD3B,PSIP1,FRMD5,MIER3,AGFG1,KCNB1,KIF2A,NCOA7,MEIS1,MXI1,LYRM9,NF1,CNOT4,NOVA1,PCDH8,POLG,CNNM2,FIGN,ROBO1,SATB1,PPM1E,FBXO11,NLGN1,EPC1,GKAP1,ATMIN,RPGRIP1L,ASXL3,REEP1,EML6,HNRNPA3,JMJD1C,FXR1" MicroRNA hsa-miR-1225-5p:mirSVR_highEffct hsa-miR-1225-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-24 7.43E-21 3.43E-24 3.16E-23 65 391 "ADD2,PWWP2A,KIAA1324,FGD2,CCDC146,PKP4,CDC14B,ATP2A2,MTMR2,IL33,CLDN10,ZFP28,DZIP3,TMEM170A,ZBTB24,KLHL3,DDX46,EXOG,DTNB,CALCRL,MRPL10,ETV1,FGF11,SEMA4D,UFM1,FAM49B,ERGIC3,STAU2,MSANTD4,MEGF10,IQGAP2,C15orf41,FAM69A,METTL21A,MYO9A,NFE2L2,NTRK2,GPR137C,PLTP,HYDIN,SAMD9,PTCH1,ELOVL2,PTPRD,FAT4,GTDC1,PBRM1,RNASEL,FAM192A,RMI1,SEMA6D,SUPT20H,ZFP30,NLGN1,ABLIM3,KDM3A,SPART,STAU1,ADAMTS17,TAL1,DICER1-AS1,UBE2H,REEP1,ZNF189,SMIM8" MicroRNA "TGTGTGA,MIR-377:MSigDB" "TGTGTGA,MIR-377:MSigDB" MSigDB 1.43E-24 8.02E-21 3.70E-24 3.41E-23 45 184 "PCDH10,NT5C3B,PRX,MADD,MARCH3,NCOA1,RNF182,JAZF1,CACNA2D2,FOXN3,QKI,ARMC8,PUM1,HDAC9,C2CD2L,CDON,EDNRB,FLNC,NBEA,GLYR1,CCDC184,RNF165,ATXN2L,NEGR1,IPO5,CAMK2N2,MMP16,SLC11A2,PRTG,GPR85,LRP12,PTPRN,ZDHHC14,RET,ATXN7,SLC6A8,NAPB,BTBD7,CPEB4,ITPRID2,PLCB1,CAMTA1,RPGRIP1L,AMACR,RICTOR" MicroRNA hsa-miR-1281:mirSVR_lowEffct hsa-miR-1281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-24 8.82E-21 4.07E-24 3.74E-23 83 618 "SYN3,ACADM,MAP4K3,MYH7B,APBA2,RGS20,ASGR1,MARK4,TMEM108,ADGRB1,RGS11,KSR1,DST,CASTOR3,VXN,EVI5L,CCPG1,PPT2,SUMF2,RUBCN,ZFYVE16,INTS1,RUSC2,RHOBTB1,DNM1,DMPK,PHF20L1,TUBD1,IGSF6,SPEG,CEP78,FKTN,APOPT1,PDLIM5,CSPG5,GAD1,GGT5,ZNF276,TNRC6A,GNAO1,GP1BB,GRIA2,SERP2,RNF165,C2orf72,KIAA1755,SCIN,SLC6A17,LINC00634,SFXN5,ADAM11,NCAM2,SMIM11A,P2RX7,PCSK5,ANKRD16,ERI2,RFX3,ST6GALNAC6,SLA,CDK5RAP2,ANKRD36,ZNF423,TSPYL2,STAU1,DIP2A,SYNE2,ARHGEF9,SYP,EXOC7,SYNE1,TIAM1,PIK3R5,NPL,C9orf85,CHST5,RUSC1,RPRM,NPDC1,TRIM9,FIP1L1,IFT88,JPH3" MicroRNA "TTTTGAG,MIR-373:MSigDB" "TTTTGAG,MIR-373:MSigDB" MSigDB 1.60E-24 8.94E-21 4.12E-24 3.79E-23 48 212 "KLHL13,ALK,PITPNM2,PKP4,TMEFF1,SLC4A4,ST3GAL5,CACNA1G,CAPN3,KRIT1,CFL2,ARMC8,CSNK1E,DNAJB6,PHF20L1,MBNL2,ING4,GABRB3,ARFIP1,PPARGC1A,RNPS1,TNRC6A,PSIP1,ELOVL5,JAK2,IPO5,MBP,MYCN,TRHDE,EPB41L4B,PPP3CA,ELOVL2,KHDRBS2,RIC8B,FBXW7,TRA2B,PPM1E,PKNOX2,SP2,NMNAT2,LARP4,CLASP1,UBE3A,FLRT2,XPO1,ZIC2,SLC17A7,PHTF2" MicroRNA hsa-miR-890:PITA hsa-miR-890:PITA_TOP PITA 1.61E-24 9.01E-21 4.15E-24 3.82E-23 51 241 "RALGAPA1,ESYT2,NCOA1,CALM1,FOXN3,LHX2,NRXN3,SLC35F1,MATR3,PITPNC1,MYEF2,ELMO1,ALKBH8,FAM107B,CPEB2,CELSR3,PLEKHA1,EPB41L2,KATNAL1,CLVS1,B4GALNT1,AHDC1,PCLO,BACH2,MIER3,IDH3A,L1CAM,MBNL1,MN1,MYCN,MYO6,MYT1,ZC3H12B,PDE1B,PIK3R1,PURG,MINDY2,PTPRB,PTPRD,TRA2B,CHD9,DOK5,RBM26,RGL1,ANKRD28,FBXW11,TRPS1,OSBP2,CELF4,POLR3H,SOCS4" MicroRNA hsa-miR-215:mirSVR_highEffct hsa-miR-215:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.70E-24 9.53E-21 4.39E-24 4.04E-23 80 579 "SLC24A4,ALCAM,FAM135A,LRCH2,PKP4,PLA2G4C,CDK13,ZBTB10,CA8,VXN,RUNX1T1,ZNF501,MTMR7,LRRFIP1,DIS3L,NDST3,ARMC8,CLIP3,GAPVD1,DDX46,ALKBH8,DNAH9,PHF20L1,DENND4A,VPS26C,NSRP1,SEC23B,SEMA4D,AFF2,ATP2C1,KHDRBS3,GAD1,GCNT2,GPT2,LPAR4,PCLO,HNF4G,KCNN2,LIMS1,LRP1B,MIA2,NEK1,NF1,NTRK2,NUCB2,PCDH9,MAPK4,BDNF-AS,MTMR10,PID1,USP47,NWD1,RIC8B,ATP8B4,ABCA11P,FBXO11,ZFP1,MYH15,LIMCH1,TRERF1,NKAIN2,SYNE2,PLCB1,ADGRL3,RPGRIP1L,PCDHGB7,PCDHB9,DICER1,ZMAT3,TIAM1,TP53BP2,TPM1,STXBP4,FAM155A,ZNF45,ZNF540,EML6,SMARCAD1,FAM47E,SMIM8" MicroRNA hsa-miR-192:mirSVR_highEffct hsa-miR-192:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.70E-24 9.53E-21 4.39E-24 4.04E-23 80 579 "SLC24A4,ALCAM,FAM135A,LRCH2,PKP4,PLA2G4C,CDK13,ZBTB10,CA8,VXN,RUNX1T1,ZNF501,MTMR7,LRRFIP1,DIS3L,NDST3,ARMC8,CLIP3,GAPVD1,DDX46,ALKBH8,DNAH9,PHF20L1,DENND4A,VPS26C,NSRP1,SEC23B,SEMA4D,AFF2,ATP2C1,KHDRBS3,GAD1,GCNT2,GPT2,LPAR4,PCLO,HNF4G,KCNN2,LIMS1,LRP1B,MIA2,NEK1,NF1,NTRK2,NUCB2,PCDH9,MAPK4,BDNF-AS,MTMR10,PID1,USP47,NWD1,RIC8B,ATP8B4,ABCA11P,FBXO11,ZFP1,MYH15,LIMCH1,TRERF1,NKAIN2,SYNE2,PLCB1,ADGRL3,RPGRIP1L,PCDHGB7,PCDHB9,DICER1,ZMAT3,TIAM1,TP53BP2,TPM1,STXBP4,FAM155A,ZNF45,ZNF540,EML6,SMARCAD1,FAM47E,SMIM8" MicroRNA hsa-miR-887:mirSVR_lowEffct hsa-miR-887:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-24 9.85E-21 4.53E-24 4.17E-23 59 325 "PWWP2A,RNF150,ALCAM,AMPD2,CASK,RASL11B,ATP2B2,DST,ZNF501,RGN,NRXN3,CNGA3,IGLON5,ARHGEF10,VCAN,SPATA2,DCTN1,POM121,GRIN3A,DMTF1,MAMLD1,DNAJB6,EDNRB,HIPK3,C3orf18,ETV1,GORAB,KHDRBS3,SARAF,C15orf41,TNRC6A,TDRKH,GRIA2,ADAMTS13,SERP2,BTN2A1,UBE2QL1,MBNL1,MYO9A,NNAT,CLDN11,PDE4D,FXYD1,PRIMPOL,MAGEL2,PPM1B,PIGG,PTPRN2,UBR7,RGS3,SGSM1,RPS6KA2,LRRK2,TNFRSF19,ZEB1,OBSL1,SIRT1,ZNF346,AMACR" MicroRNA hsa-miR-146b-5p:TargetScan hsa-miR-146b-5p TargetScan 1.81E-24 1.01E-20 4.66E-24 4.29E-23 46 194 "ESYT2,PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP2,QKI,CNTFR,ARMC8,FAM169A,APPL1,RIMS2,IST1,DGKG,DNAL1,CDON,RCAN1,EDNRB,HIPK3,HEYL,EIF4G2,ERBB4,CELF1,GPR75,KDM2B,MAPT,MARK1,MMP16,LAYN,MYO5A,MYO6,MYT1,NOVA1,KCTD15,ERI2,RNASEL,ROBO1,GALNT10,HSPA4L,KBTBD4,FAM208A,NSD1,FRYL,POLR3H" MicroRNA hsa-miR-146a-5p:TargetScan hsa-miR-146a-5p TargetScan 1.81E-24 1.01E-20 4.66E-24 4.29E-23 46 194 "ESYT2,PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP2,QKI,CNTFR,ARMC8,FAM169A,APPL1,RIMS2,IST1,DGKG,DNAL1,CDON,RCAN1,EDNRB,HIPK3,HEYL,EIF4G2,ERBB4,CELF1,GPR75,KDM2B,MAPT,MARK1,MMP16,LAYN,MYO5A,MYO6,MYT1,NOVA1,KCTD15,ERI2,RNASEL,ROBO1,GALNT10,HSPA4L,KBTBD4,FAM208A,NSD1,FRYL,POLR3H" MicroRNA hsa-miR-513c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-24 1.02E-20 4.70E-24 4.33E-23 45 185 "FZD9,SPOP,ZNF582,BACH1,ZNF555,HDAC4,EDN3,ENPP6,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,CCSER2,KANSL1,PRKACB,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,CEP68,DICER1,TRPS1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-518d-3p:mirSVR_lowEffct hsa-miR-518d-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.91E-24 1.07E-20 4.90E-24 4.51E-23 77 541 "NDRG3,FMNL2,PSMG3-AS1,RNF150,OLMALINC,KLHL13,ASGR1,FUBP1,THSD7A,PRC1,CCPG1,SRSF11,SOCS6,QKI,SULT4A1,MAP4K4,ARHGEF6,COL9A1,MYRIP,ZNF521,AKAP12,ANKRD44,GDA,KCTD8,DAPK1,DGCR5,RHOBTB1,DMPK,SLC29A4,CDON,EDN1,SEMA3D,EIF1,IP6K2,FLT1,NELFCD,SDCBP2,NEURL4,TUBA8,PCLO,AGBL5,MPP2,LYRM9,MYO6,RTL5,NME4,OPA1,PFKFB2,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,SCN2B,HSPA4L,CPEB4,PDZRN3,KDM3A,ADHFE1,AGTPBP1,MGRN1,ZEB1,RIMBP2,RGMB,TRIO,TSC1,UCHL1,CELF4,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-let-7c-5p:Functional MTI Functional MTI miRTarbase 2.04E-24 1.14E-20 5.24E-24 4.82E-23 75 516 "FZD9,MTUS1,ZNF578,CDC42BPA,MAP4K3,AQP6,IGDCC4,NUMB,ATP2A2,BACH1,QKI,TMEM184B,ARMC8,CREM,CRY2,IP6K1,DNAL1,MTX3,DNAH9,E2F5,E2F6,EDN1,ANKRD46,EIF4G2,FOXO3,TRMO,PDLIM5,CELF1,DOT1L,DISC1,GATM,SRCAP,COPS8,POLL,FUT10,RABL2A,IL6R,KPNA5,CHST6,MEF2C,THYN1,MYO9A,NME4,NPTX1,SLC11A2,NUCB2,OPRL1,PPP2R5E,CNNM2,PTK2,QDPR,USP47,RDX,FIGN,SAFB,ATXN2,KIF27,FNDC3A,R3HDM2,SLC12A2,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,DICER1,SIRT1,CBX5,BHLHB9,TUBB2A,SLC35A4,RICTOR,ZNF28,SMARCAD1" MicroRNA hsa-miR-95:mirSVR_lowEffct hsa-miR-95:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.24E-24 1.25E-20 5.74E-24 5.29E-23 62 360 "CLK4,PWWP2A,WDR35,AMPD2,EP400,ARRB1,SEC11C,DST,MYRF,CALM1,CCPG1,NRXN3,CNRIP1,AKAP12,PITPNM3,BOC,ARMCX2,WDR20,SEC16A,DMD,DMTF1,DNAJB6,MBNL2,AGAP3,PRELID3A,MPP6,ZNF559,CYP46A1,MMADHC,TDRKH,GRM8,AP4S1,HAS2,TJAP1,SLC35G1,KCND2,GLIPR1L2,PDE4A,SH3TC2,RASGRF2,RBBP8,KIAA0895L,TCP11L1,ATAT1,ATXN2,NAPB,DMRTC1,LIMCH1,ATP10B,ELOVL4,SLC19A3,PCDHA1,SIK3,SLC44A1,HEY1,AMACR,RUSC1,BCL2L13,ZNF708,ZNF154,EMSY,EVI5" MicroRNA hsa-miR-518f:mirSVR_lowEffct hsa-miR-518f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-24 1.31E-20 6.00E-24 5.52E-23 81 595 "NDRG3,FMNL2,PSMG3-AS1,RNF150,OLMALINC,ASGR1,FUBP1,THSD7A,KALRN,CCPG1,SRSF11,SOCS6,QKI,SULT4A1,MAP4K4,ARHGEF6,COL9A1,MYRIP,ZNF521,AKAP12,ANKRD44,GAPVD1,KCTD8,DAPK1,DGCR5,DMPK,SLC29A4,CDON,EDN1,EIF1,MRPL37,MED12L,IP6K2,NELFCD,SDCBP2,TUBA8,PCLO,AGBL5,SYTL4,MAP6,MPP2,LYRM9,RTL5,NME4,OPA1,PFKFB2,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,SCN2B,HSPA4L,CPEB4,IFT122,PDZRN3,KDM3A,SEPT8,STAC2,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,ZMAT3,RIMBP2,TRIO,TSC1,UCHL1,CELF4,ZFAND5,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-191:mirSVR_highEffct hsa-miR-191:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.34E-24 1.31E-20 6.01E-24 5.53E-23 61 349 "PWWP2A,AP2A2,PITPNM2,CACNA1B,CCPG1,B4GALT6,NCOR1,PHACTR3,LIN54,DAPK1,DPP6,COPS4,DCTN4,EMX2,F5,CEP78,AMOTL2,NEURL4,RAPGEF6,PPARGC1A,TJAP1,MBD1,NRCAM,ZNF655,PLCD1,MAGEL2,PPP2R5E,MAPK9,PIGG,PTPRD,RAP1GDS1,RGS3,C12orf49,ROBO1,ARMH4,RPS20,SAFB,SATB1,FHOD3,TET1,LIMCH1,CMTR2,ATP10B,MPRIP,ELOVL4,RGL1,NUDT10,COBL,TCEA1,SIN3B,SATB2,ZEB1,PCDHB9,HEY1,C9orf85,UBE3A,ZNF154,UPF3A,MAP3K12,PARP11,KAT6A" MicroRNA hsa-miR-485-5p:TargetScan hsa-miR-485-5p TargetScan 2.42E-24 1.36E-20 6.21E-24 5.72E-23 58 316 "BEND6,AMPD3,OGT,CDC42BPA,PPFIA4,CCAR2,KSR1,CAMK2A,LRRFIP1,DLGAP2,PLXNA4,ELMSAN1,DNM1,DPH1,DRP2,PLXNC1,RASL10A,CELF1,GABRB3,GGT7,PPARGC1A,PTPRT,ATOH8,FRMD5,DDX19B,DISP2,KCNK3,CAMK2N2,AFF1,DBNL,HS6ST3,MXI1,NOVA1,PDE3A,PLEC,FSD1,POU6F1,NKAIN4,MAPK4,BCAS3,CYB561D1,PEAR1,CHD9,PEX26,NMNAT2,PEG10,DDN,MMS19,ARHGAP9,HIF3A,FAM124A,MGAT5B,LYPD6,REEP1,CADM2,NELFE,PARP11,JMJD1C" MicroRNA hsa-miR-521:mirSVR_lowEffct hsa-miR-521:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-24 1.37E-20 6.25E-24 5.76E-23 63 372 "AXIN2,USP31,ZFAT,INSYN2B,TTLL9,DDR1,AKAP6,SMARCAL1,ENTPD4,CRMP1,HAPLN1,SNCAIP,OSBPL3,USP6NL,ARHGAP24,DAPK1,SPOCK2,LYPD1,DPP6,ECM2,MRPL37,GTF2IRD2,FGF13,PDLIM5,FAM49B,CELF1,FYB1,GHR,GLI2,KIAA1958,PLPP7,AP4S1,SLC2A6,DDX19B,HMGCL,AGBL5,IRF8,IL6ST,MID1,MYO6,NEFH,NUCB2,NLE1,POU6F1,ELOVL2,ZIK1,PTPRD,PTPRE,CASTOR1,PPP4R3A,BTBD3,SLC12A2,RBM34,CLSTN2,PDLIM2,TCF4,VWCE,METTL3,UGT8,POLR3H,MEIS3,CASC15,TRAM2-AS1" MicroRNA hsa-miR-766-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.53E-24 1.41E-20 6.47E-24 5.96E-23 82 609 "XKR4,SLC24A4,HACE1,KIAA1324,TXNDC16,TNRC6C,AQP6,CDC14B,ARSE,ZNF555,CBS,SLC16A4,SOCS6,NRXN3,SUSD5,UBXN2A,FAM131B,CENPL,TMEM170A,DNAL1,MTX3,TMCC2,NR1D2,ABCC5,EBI3,EPB41,EZH1,ANKFY1,TRMO,RAPGEF6,ZNF234,CRCP,GPR75,DDX19B,AGBL5,CELF5,SOWAHA,KIAA1755,ZNF678,CREG2,CHST6,MID1,ZC3H12B,SLC11A2,CCSER2,PKM,MTRF1L,TATDN3,STK32A,TMEM145,KLHL11,KLHDC8A,ALG9,ELP2,ATAT1,NCBP3,ZNF331,SEPHS1,RADIL,ZNF667,SNAP25,FAM126B,MCF2L2,SSTR2,APOM,DNMBP,ARL10,PARD3,SMUG1,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,TBC1D15,ZNF138,SLC30A4,TRIM16L,WNK2,GAN,SPATA13" MicroRNA hsa-miR-4279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.69E-24 1.50E-20 6.87E-24 6.33E-23 73 493 "AS3MT,RNF157,ZNF578,CDC14B,SEMA4G,DNAH17,SLC4A4,ALDH7A1,IGLON5,HINFP,RGS6,CSNK1E,KIAA0408,USP3,WDPCP,CNNM1,HEYL,OPTN,MRO,MRNIP,RGS17,EMX2,EPHB1,SLC43A2,FKTN,FDFT1,FOXO3,AFF2,CELF1,PCDH17,CRCP,KIAA1958,RNF165,ZDHHC15,NEGR1,EID2B,C2CD4C,KPNA5,LAMP2,LIMS1,NCOA7,LSAMP,AFF1,NPTX2,FAM216A,POU6F1,EPDR1,APTX,PTPRB,TMEM231,ZNF844,NWD1,GTDC1,PGBD4,FAM192A,SCN2B,STUM,ZFP30,PEX26,UHRF1BP1L,UNC5B,AGTPBP1,TPCN2,PCDHA6,ZNF106,ARL10,TLR4,ERCC6L2,TNS1,AGMO,ZNF70,MPPE1,GAN" MicroRNA hsa-miR-513a-3p:Functional MTI Functional MTI miRTarbase 2.96E-24 1.66E-20 7.57E-24 6.97E-23 45 187 "FZD9,SPOP,ZNF582,BACH1,ZNF555,HDAC4,EDN3,ENPP6,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,CCSER2,KANSL1,PRKACB,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,CEP68,DICER1,TRPS1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 3.14E-24 1.76E-20 8.02E-24 7.39E-23 70 457 "TMCC3,MTA3,ZNF608,OGT,EP400,ATP1A1,BID,CFLAR,DST,ARHGEF1,BAG4,RBM39,PDE4DIP,KIAA0408,SCRN1,GIT2,ZBTB24,RHOBTB1,SACS,USP3,CPEB2,EIF4G2,EIF5,RGS17,DCTN4,TBC1D16,ST3GAL6,FKTN,FER,FOXO3,MALT1,TNRC6A,MSL3,ZBTB45,EID2B,IGF1,SMAD1,MAT2A,ZNF680,BLOC1S2,PDE4B,OLA1,PIK3C2A,ZNF426,MTRF1L,PSAT1,RETREG2,PTPN13,NWD1,SLC25A36,ARMH4,SARS,CPEB3,FBXO11,SEC31A,PPP4R3A,BTBD3,CPEB4,TMCC1,FAM126B,DIP2A,DNMBP,ALG1,AGTPBP1,ASXL3,AMACR,SSBP2,UBE2H,SLC35A4,UBTF" MicroRNA "ATACCTC,MIR-202:MSigDB" "ATACCTC,MIR-202:MSigDB" MSigDB 3.56E-24 1.99E-20 9.09E-24 8.37E-23 43 170 "XKR4,PCDH19,ZBTB10,BCL7A,DST,FOXN3,CHN2,NDST3,ARMC8,MYRIP,CREM,SEC24C,KIAA0040,ZC3H11A,CPEB2,DUSP9,STARD3NL,DLC1,IP6K2,GAD1,GHR,PPARGC1A,RNF165,HAS2,SMAP1,LAMP2,HECTD2,MYCN,XRN1,PURG,LRRN3,LAMA1,CPEB3,CPEB4,SOX11,HECW1,SYT1,KIAA0930,DICER1,CSMD1,SLC30A4,ADAMTS9,KAT6A" MicroRNA hsa-miR-301b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 3.82E-24 2.14E-20 9.75E-24 8.98E-23 63 375 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,DAPK1,SEC16A,DPYSL2,EDN1,TMTC1,EGFR,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PTPRG,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1" MicroRNA "CTGAGCC,MIR-24:MSigDB" "CTGAGCC,MIR-24:MSigDB" MSigDB 3.82E-24 2.14E-20 9.75E-24 8.98E-23 48 216 "RNF150,LRFN2,TAOK1,PCDH10,OGT,MARK4,HAP1,VXN,HIP1R,RHBDL1,MAGI1,CNTFR,COL11A2,RASSF2,MATR3,KLHL3,TMCC2,SLC12A6,FAM78B,PHF20L1,SCML2,DLC1,FGFR3,AMOTL2,IP6K2,SESN1,PCDH17,RNF165,INPP5B,SFXN5,MMP16,MXI1,NELL2,MBOAT7,MAPK7,PTPRD,TNFRSF19,DHX30,DDN,POGZ,NEK4,SYP,SZT2,TMEM9,PLPPR2,VAV1,ZXDA,GAL3ST3" MicroRNA hsa-miR-1207-3p:PITA hsa-miR-1207-3p:PITA_TOP PITA 3.83E-24 2.14E-20 9.78E-24 9.01E-23 54 276 "FZD9,PCDH19,TAOK1,MARK4,RUNX1T1,ZMYM4,DLGAP2,CACNA2D2,CFL2,PPP1R16B,GPRASP1,DCAF8,IST1,RUSC2,MBNL2,ENO2,ERBB4,SPEG,BAIAP2,NBEA,MEGF11,SRRM4,SRCAP,TTBK1,TMEM121B,CIT,L1CAM,MAPT,MSI1,MYO6,MYO9A,NEXMIF,NBL1,NFIX,NOVA1,ZNF827,PIK3R1,RASGEF1B,TMEM255A,SETD5,CYB561D1,PRCD,TNFRSF19,SGK1,NKAIN2,STX1A,SULF2,ANKRD28,CUX2,SZT2,TNS2,HEY1,RELL2,URM1" MicroRNA "ATGTAGC,MIR-221:MSigDB" "ATGTAGC,MIR-221:MSigDB" MSigDB 3.89E-24 2.17E-20 9.91E-24 9.12E-23 38 129 "RALGAPA1,AXIN2,LRFN2,OGT,ATP1A1,KSR1,QKI,ZNF385A,FAM13A,PPARGC1A,FERMT2,AGFG1,LIFR,HECTD2,ADAM11,MEIS1,NOVA1,KANSL1,MAPK10,ANKHD1,KHDRBS2,SEMA6D,KIF16B,FNDC3A,SYBU,TMCC1,CDK19,POGZ,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,TRPS1" MicroRNA "ATGTAGC,MIR-222:MSigDB" "ATGTAGC,MIR-222:MSigDB" MSigDB 3.89E-24 2.17E-20 9.91E-24 9.12E-23 38 129 "RALGAPA1,AXIN2,LRFN2,OGT,ATP1A1,KSR1,QKI,ZNF385A,FAM13A,PPARGC1A,FERMT2,AGFG1,LIFR,HECTD2,ADAM11,MEIS1,NOVA1,KANSL1,MAPK10,ANKHD1,KHDRBS2,SEMA6D,KIF16B,FNDC3A,SYBU,TMCC1,CDK19,POGZ,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,TRPS1" MicroRNA hsa-miR-3666:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.11E-24 2.30E-20 1.05E-23 9.64E-23 62 364 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,DAPK1,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PTPRG,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1" MicroRNA hsa-miR-3653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.15E-24 2.32E-20 1.06E-23 9.73E-23 83 627 "AS3MT,TMEM132B,ELFN2,RNF157,TAOK1,CDC14B,SLC4A4,ALDH7A1,STOML1,CREM,ENTPD4,HINFP,CSNK1E,RIMS4,KIAA0408,MYADM,DNAL1,WDPCP,CNNM1,MRNIP,RGS17,SLC43A2,FKTN,FDFT1,FOXO3,AFF2,SRCAP,CRCP,KIAA1958,RNF165,HAS2,DDX19B,ZDHHC15,EID2B,C2orf72,METTL21A,KCNN1,KCNN3,NCOA7,MAN2A2,CHST6,P2RX7,TMOD2,PIK3C2A,EPDR1,APTX,PIGG,ZSCAN2,TMEM231,ZNF844,NWD1,GTDC1,DCUN1D2,PGBD4,FAM192A,SCN2B,HSPA4L,ZFP30,NUBPL,PEX26,ZNF430,ZNF667,ANKRD36,FAM126B,ZBTB43,SSTR2,MPRIP,STAC2,AGTPBP1,SATB2,TPCN2,PCDHA6,ZNF34,ZNF106,ARL10,ERCC6L2,SGK3,USP1,AGMO,ZNF70,MPPE1,PHTF2,GAN" MicroRNA hsa-miR-24-1*:mirSVR_highEffct hsa-miR-24-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.20E-24 2.35E-20 1.07E-23 9.86E-23 65 399 "NCKAP5,KLHL32,CC2D2A,SMIM17,ARHGAP20,CCDC146,LGR5,ZSCAN18,BTK,CALB1,CALM1,ZMYM4,SRSF11,ARMC8,ARHGEF10,CYBB,DOCK4,GAPVD1,RAB39B,DTNB,EMX2,ABCA8,MEX3B,TUBGCP4,TUBA8,KDM2B,PLCD4,ADAMTS6,GUCY1B1,HAS2,IGF1,MYO9A,NCAM2,VWA2,CHAMP1,PCDH9,TMEM260,ENOX1,OXR1,TNFRSF19,SCAF8,FERMT1,TET1,CPEB4,CDK5RAP2,MYH15,LIMCH1,SNRPN,PDZD2,BDP1,ATP10B,SSTR1,ERBIN,ANKRD28,TCF12,DOCK9,NSD1,BHLHB9,WIPF1,ZNF711,LYPD6,HNRNPA3,PHTF2,RNF170,RNF146" MicroRNA hsa-miR-1183:PITA hsa-miR-1183:PITA_TOP PITA 4.57E-24 2.56E-20 1.16E-23 1.07E-22 46 198 "PTCHD1,ZNF608,RTL9,TAOK1,CDC42BPA,APC,CADPS,ZBTB10,KALRN,SRSF11,QKI,HECTD1,CNN3,CREM,PLCXD3,SEZ6L2,RGS17,SUCO,HPCAL4,GABRB3,MSTN,PCDH17,GHR,PCLO,GRIA2,NEGR1,AGFG1,LRP1B,MID1,PDE4B,KCTD15,LRRN3,PTCH1,PTPRD,PTPRO,RORB,ATXN2,TMCC1,SPTB,NKAIN2,TCF4,TRPS1,OSBP2,FZD3,HNRNPA3,SOCS4" MicroRNA hsa-miR-146b-5p:PITA hsa-miR-146b-5p:PITA_TOP PITA 4.59E-24 2.57E-20 1.17E-23 1.07E-22 43 171 "ESYT2,AMPH,CASK,MARK4,NUMB,SYNJ1,JAZF1,RUNX1T1,CCK,DLGAP2,DLGAP1,RCHY1,APPL1,USP3,ABCC5,EIF4G2,ERBB4,SCML2,SARAF,TDRKH,PCLO,MAPT,MARK1,MYO5A,ZC3H12B,NOVA1,KCTD15,TMEM255A,USP47,RIC8B,ZNF532,SNX22,WDR47,PEG10,CLASP2,SYT1,RPGRIP1L,FRYL,ZIC1,TRIM9,POLR3H,CADM2,PCBP4" MicroRNA hsa-miR-146a:PITA hsa-miR-146a:PITA_TOP PITA 4.59E-24 2.57E-20 1.17E-23 1.07E-22 43 171 "ESYT2,AMPH,CASK,MARK4,NUMB,SYNJ1,JAZF1,RUNX1T1,CCK,DLGAP2,DLGAP1,RCHY1,APPL1,USP3,ABCC5,EIF4G2,ERBB4,SCML2,SARAF,TDRKH,PCLO,MAPT,MARK1,MYO5A,ZC3H12B,NOVA1,KCTD15,TMEM255A,USP47,RIC8B,ZNF532,SNX22,WDR47,PEG10,CLASP2,SYT1,RPGRIP1L,FRYL,ZIC1,TRIM9,POLR3H,CADM2,PCBP4" MicroRNA hsa-miR-675:mirSVR_lowEffct hsa-miR-675:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.94E-24 2.77E-20 1.26E-23 1.16E-22 66 412 "TAOK1,SUGT1P4-STRA6LP-CCDC180,ARNTL,MARK4,ATP2B2,LINC00847,CA4,CAMK2B,ASIC3,TAOK2,NRXN3,PPT2,MAP4K4,IGLON5,CNTFR,LETMD1,ZNF385A,HINFP,RUBCN,HDAC9,HS3ST2,SLC29A4,EPB41L2,SPEG,RACK1,OLFM1,FGF13,SCARA3,AGAP2,SEMA4D,DLL3,SIGLEC8,RNPS1,STARD3,AP4S1,IRF8,MYO7A,ALDH1L2,CDK18,PKD1,PLIN1,MAPK4,BCAS3,GTDC1,UBR7,SNX22,ZNF568,PEAR1,MYO18A,WDR37,SLC6A8,SLC22A4,CPEB4,MYO16,SSTR1,SSPO,JMJD6,SYN1,PDLIM2,PCDHB9,ITGB3BP,PPIL6,SLC35A4,NDRG4,LINC02210,URM1" MicroRNA hsa-miR-136:PITA hsa-miR-136:PITA_TOP PITA 5.17E-24 2.90E-20 1.32E-23 1.21E-22 52 257 "SYN3,PWWP2A,MAP4K3,APAF1,USP37,CDC14B,ZFYVE28,ZBTB10,JAZF1,KALRN,CAMK2G,CCPG1,CACNA2D2,FOXN3,AKAP5,SH2B1,RIMS2,CPEB2,APH1A,MBNL2,COPS4,EYA1,MEGF10,SRRM4,GATM,PPARGC1A,TNRC6A,MIER3,KCND1,HS6ST3,NEXMIF,ZC3H12B,NOVA1,PIK3R1,STRN3,MINDY2,SNRK,TMEM260,PTPN13,PTPRG,RET,RGS4,RORB,RYR3,PPP4R3A,CPEB4,RCOR3,NECAB1,ADGRL3,RPGRIP1L,VLDLR,PRDM8" MicroRNA hsa-miR-4295:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-24 3.11E-20 1.41E-23 1.30E-22 62 366 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,DAPK1,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PTPRG,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1" MicroRNA "GTCTTCC,MIR-7:MSigDB" "GTCTTCC,MIR-7:MSigDB" MSigDB 6.26E-24 3.50E-20 1.59E-23 1.46E-22 41 155 "OGT,PPFIA3,SLC4A4,ATP2B2,FOXN3,CNOT8,CNN3,CRY2,BOC,SPATA2,EGR3,ERBB4,ACSL4,HPCAL4,ANKFY1,GABBR1,MAP4,ADAM11,SCAMP5,CHAMP1,PAX6,PDE4D,CCSER2,PLEC,MAPKAP1,STRN3,PRKCB,MAPK4,PTK2,OXR1,SEMA6D,SATB1,SCN2B,AMBRA1,WDR47,CLASP2,ANKRD12,TCF12,LRRC8A,FLRT2,GAL3ST3" MicroRNA hsa-miR-129-3p:PITA hsa-miR-129-3p:PITA_TOP PITA 6.44E-24 3.60E-20 1.63E-23 1.50E-22 50 238 "XKR4,ADD2,KLHL13,USP6,DGKI,DLGAP2,NUMBL,RCBTB2,HECTD1,RCHY1,SEC24C,PLCXD3,SPATA2,MYEF2,POM121,RHOBTB1,SACS,RCAN2,FGF13,GRIN2D,PTPRT,FRMD3,NEK1,GPR137C,SEMA5B,PIK3R1,POLG,PKIA,MAPK3,ELOVL2,RIPOR1,GTDC1,UBR7,ZNF532,ROBO1,SNX22,BAALC,ABLIM3,NMNAT2,ERBIN,CLASP1,FRYL,TIAM1,HEY1,FAM155A,FLRT2,ZBTB38,REEP1,NAV3,PHTF2" MicroRNA hsa-miR-135a*:mirSVR_highEffct hsa-miR-135a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.05E-24 3.94E-20 1.79E-23 1.65E-22 86 673 "CC2D2A,ALCAM,LRFN1,SLC4A4,RNF182,SYNJ2,SGCE,CAMK2G,ARHGEF25,KRIT1,LRRFIP1,MAGI1,PPT2,CLCN3,ARMC8,SLC4A8,CTH,DOCK4,MYADM,ARHGAP24,TMEM170A,KIAA0319,CPEB2,EDIL3,TMTC1,PHF20L1,FOXO3,PDLIM5,TPK1,OGA,GABRG2,PPARGC1A,RUNDC3A,GLUL,GNAL,ZNF782,PADI2,TCEAL6,MSL1,IL6R,ZNF678,LYPLAL1,NELL2,DNHD1,DPY19L2P2,GNG2,PURG,PPP2R2B,KANSL1,HYDIN,PTPRG,RAD51D,RAP1GDS1,RADX,RGS4,RIC8B,RNASEL,ZFHX4,C12orf49,ZNF568,CCDC112,ATXN7,SHC4,WDR47,ZFP1,SPART,CLSTN2,ITPRID2,ZNF302,PHLDB1,C12orf76,AGTPBP1,SYNE1,PCDHB9,PCDHB4,MTMR14,TMPO,WBP2,SYNPO2,HIRA,WIPF1,KLC2,REEP1,PRDM10,NAV3,NETO2" MicroRNA "CATGTAA,MIR-496:MSigDB" "CATGTAA,MIR-496:MSigDB" MSigDB 7.08E-24 3.96E-20 1.79E-23 1.65E-22 42 164 "KCNH8,ESYT2,HACE1,SEMA6A,DPP10,DPY19L3,BACH1,LDB2,B4GALT6,QKI,LRIG1,CNTNAP2,SLITRK5,PHF14,DMD,YAF2,OLFM1,NBEA,KHDRBS3,GRIA2,BACH2,LAMP2,HECTD2,MAP2,MAT2A,MEF2C,MEIS2,PDE3A,PURG,LRRN3,MAPK9,SLC25A36,ROBO1,ZNF331,SEMA6D,CPEB4,CLASP2,CAMTA1,SATB2,ZIC1,PRDM10,NAV3" MicroRNA hsa-miR-298:PITA hsa-miR-298:PITA_TOP PITA 7.13E-24 3.99E-20 1.81E-23 1.66E-22 53 269 "NDRG3,NDRG2,SEMA6A,ALCAM,APBB2,ARHGDIA,ZBTB10,NCOA1,CA12,HAP1,SPAG9,SOCS5,SPOCK2,DCTN1,MYEF2,CPEB2,DUSP9,EIF4G2,RCAN2,ETV1,DNAJC27,FHL1,CSPG5,PCDH17,PPARGC1A,RNF165,MIER3,CAMK2N2,MEF2C,MN1,PDE4B,ANKRD16,CEP41,PRCD,FBXO11,PPP4R3A,CCDC88A,LGI3,TEX2,CDK19,POGZ,ANKRD28,ADGRL3,ZEB1,TCF12,DICER1,ITGB3BP,SH3GLB2,ZFAND5,SMARCAD1,KCNAB1,RGS7BP,NETO2" MicroRNA "CACCAGC,MIR-138:MSigDB" "CACCAGC,MIR-138:MSigDB" MSigDB 7.18E-24 4.02E-20 1.82E-23 1.68E-22 46 200 "UNC5A,NCOA1,CASTOR3,JAZF1,CBFA2T2,CNOT8,ZNF385A,SLC35F1,OSBPL3,HDAC4,MYEF2,DNAJB6,KMT5B,RCAN2,CLVS1,BAIAP2,NBEA,SRRM4,PPARGC1A,GLI2,FERMT2,CIT,MOV10,MSI1,NFIX,NPTX1,PDE3A,EPB41L4B,VSTM2L,RELN,PTK2,USP47,SLC6A8,KBTBD4,CPEB4,SPTB,IQSEC2,ADGRL3,KIAA0930,SIRT1,TRPS1,MGAT5B,SLC17A7,KAT6A,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-4323:mirSVR_highEffct hsa-miR-4323:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.48E-24 4.18E-20 1.89E-23 1.74E-22 66 415 "ADD1,SUGT1P4-STRA6LP-CCDC180,MAGEE2,AQP6,KSR1,NAE1,DDR1,CAMK2G,LARGE1,MAGI1,CSF1R,PDE4DIP,FAM169A,SLITRK5,CTH,RIMS2,USP6NL,C2CD2L,SLC25A18,PHC2,RASGRP1,VPS13B,TLR7,SH3YL1,SCML2,FGFR1,ATP13A4,ATP2C1,GAD1,NEU3,TNRC6A,STON1,GRIA2,NKD1,MEIS1,AFDN,CHAMP1,PCDH9,NALCN,PLIN1,RELN,TMEM260,PTPRB,PRRT2,GTDC1,RORB,DGLUCY,KBTBD4,EPC1,SNRPN,UHRF1BP1L,KDM4C,ATP10B,ZSCAN29,SEPT8,ADAMTS17,COBL,CAMTA1,OBSL1,TPM2,RPL7L1,UBTF,FLRT2,CIAPIN1,EPM2A,FBXO36" MicroRNA hsa-miR-345:mirSVR_highEffct hsa-miR-345:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.68E-24 4.30E-20 1.94E-23 1.79E-22 76 540 "PLEKHH1,INTS2,ZNF578,PCDH10,PHF12,UPRT,KSR1,SCAPER,CACNB4,USP6,NUMBL,SRSF11,PPT2,FBXO7,TOGARAM2,CRMP1,MROH8,SEC24C,USP6NL,CYBB,GPRASP1,DDX46,CHRDL1,E2F6,FAM13A,APH1A,KMT5B,ASB3,EPB41L2,ADGRV1,SCML2,IP6K2,DLL3,STAU2,ADAM28,GFRA2,RNPS1,ZNF638,LOXL3,FAM19A2,AP4S1,HMGCL,NCOA7,PACRG,SMAD1,KITLG,NFE2L2,NUCB2,OPA1,PDE4B,MAPKAP1,GDPD2,STK32A,STRC,FIGN,PBRM1,ELP2,ASAP3,SLC2A5,MBD5,KDM4C,ATP10B,SSTR2,NUDT10,SYP,ADGRL3,ZEB1,SIK3,SSBP2,CCDC136,LAT2,ZNF45,MKRN3,RTN4,SMIM8,GAN" MicroRNA hsa-miR-659:PITA hsa-miR-659:PITA_TOP PITA 7.81E-24 4.37E-20 1.98E-23 1.82E-22 51 249 "USP31,NCOA1,CACNB4,KALRN,CBFA2T2,ARHGEF2,SEPT7,CNN3,CABP1,SLC35F1,NCOR2,RGS6,ARHGEF10,SLITRK5,JAKMIP2,MFAP3L,FAM107B,CLVS1,SCML2,CEP78,FGF12,HPCAL4,PPARGC1A,LYVE1,RNF165,NEGR1,MAP2,NFIX,PCSK1,PRTG,PIK3C2A,PIK3R1,MINDY2,MAPK9,RELN,SNRK,HUNK,SEMA6D,FNIP1,NLGN1,SLC12A2,TMCC1,CDK19,FAM208A,TCF4,TCF12,DOCK9,SLC30A4,ITM2C,FRMD6,DPF3" MicroRNA hsa-miR-375:Functional MTI Functional MTI miRTarbase 8.32E-24 4.65E-20 2.10E-23 1.94E-22 71 477 "USP31,OSBPL8,SPOP,ARHGDIA,NUMB,INSYN2B,EIF4G3,SPAG9,ZBED1,CRLF1,CFL2,CHGB,RAB28,CNN3,AKAP7,SEC24C,SNPH,TBC1D5,TMEM170A,ANKRD46,PHF20L1,GPHN,ERBB2,RRAGB,ACSL4,SYNCRIP,NELFCD,C15orf41,SESN1,PSIP1,ATOH8,RASSF8,RBPJ,DISP2,JAK2,KHK,NCOA7,AQP11,POC1B,MYCN,IDNK,OPA1,NLE1,MAPKAP1,MINDY2,MAPK3,TMEM145,PPP2R3C,RBBP8,YY1AP1,DGLUCY,CCDC88A,GKAP1,FAM126B,NXT2,NSFL1C,KLHL7,AGTPBP1,IQCE,RPGRIP1L,TCF12,FAM200B,THRA,HEY1,TNS1,TRPS1,UBE3A,USP1,ZNF540,PHTF2,NETO2" MicroRNA hsa-miR-4284:mirSVR_highEffct hsa-miR-4284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.32E-24 4.65E-20 2.10E-23 1.94E-22 71 477 "RALGAPA1,ACADM,MTUS1,CC2D2A,FAM135A,PARG,TNRC6C,STK33,ZNF599,NAE1,SCARB1,NRXN3,SH2B1,CSF1,CSF2RA,ERC2,SGSM2,EXOG,SLC25A18,DNAJB6,AASDH,TMEM35A,CORO2B,SPSB4,AGAP3,GAD1,SULT1C4,AHDC1,GRIA2,RABL2A,FAM107A,RNFT2,ADAMTS6,ZNF491,FAM95B1,INPP5B,MATN3,COL28A1,RETREG1,JAKMIP1,ING3,GDPD1,MASP1,ELOVL2,PTPRO,TMEM231,ACSS3,GAL3ST4,FERMT1,FNDC3A,NUBPL,ELMO2,TET1,MYH15,ZC3H13,ZC4H2,SYN2,PCDHB6,SIK3,NPL,STXBP4,RPL7L1,WIPF1,XPO1,XRCC4,ZNF24,TRIM9,MKRN3,DOCK8,RNF170,IFT88" MicroRNA "CAGCACT,MIR-512-3P:MSigDB" "CAGCACT,MIR-512-3P:MSigDB" MSigDB 9.12E-24 5.10E-20 2.30E-23 2.12E-22 40 148 "SPOP,PCDH10,PITPNM2,ATP2B2,PTBP2,USP6,FOXN3,QKI,ARHGEF10,KLHL3,SGSM2,MBNL2,ETV1,OGA,PTPRT,HLF,MAT2A,MBNL1,SEMA5B,TRHDE,RETREG2,PPP2R5E,PPP3CA,USP47,ATXN7,IZUMO4,CDK19,CAMTA1,TAL1,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZNF24,MARCH8,KAT6A" MicroRNA hsa-miR-10a:mirSVR_highEffct hsa-miR-10a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.64E-24 5.40E-20 2.44E-23 2.24E-22 81 608 "KIAA1211,ALCAM,LTBP4,FAM135A,CCDC146,UPRT,IGDCC4,ALDH7A1,DOCK11,SGCE,NFS1,CCNH,CNTFR,CNTN1,ABI3BP,SLC35F1,SEC31B,NCOR2,RIMS2,USP6NL,GAPVD1,KIAA0753,DDX46,EDN3,FCF1,YAF2,PHF20L1,EGFR,EIF1,SCML2,RACK1,CEP78,SYNCRIP,UFM1,ATP6V1H,GAD1,TUBGCP4,C1QL4,RNF165,ZHX1,HMGCR,SMAP1,LIMS1,EFHB,AFDN,MYO9A,CNOT4,SLC10A4,XRN1,FAM216A,PURG,LRP12,EPB41L4B,VPS13C,ELOVL2,ERI2,FIGN,SPIN3,STK32B,ATXN2,SEC14L1,CCDC88A,ZNF667,RCOR3,PDZD2,DOK5,POGZ,NXT2,PRRC2C,DNAJC9,TRIM2,SYNE1,PUM2,FAM200B,TIAM1,DCBLD1,ZNF154,ZNF189,SLC30A4,WNK3,PDSS2" MicroRNA hsa-miR-370:PITA hsa-miR-370:PITA_TOP PITA 9.72E-24 5.44E-20 2.45E-23 2.26E-22 43 174 "ASIC1,XKR4,PCDH19,RTL9,TAOK1,USP37,CASK,SLC4A4,JAZF1,MAGI1,SRSF11,MAP4K4,HAPLN1,RIMS4,ARHGEF4,DOCK4,DRP2,PHC2,PSD2,NTNG2,PRRC2B,CIT,ADAMTS6,ATXN2L,MBNL1,MYO6,PPP5C,VSTM2L,USP47,RAP1GDS1,STX1B,STUM,FAM102A,NFASC,CLASP2,EXOC7,DICER1,DCBLD1,CCDC136,POLR3H,PRDM10,NAV3,KAT6A" MicroRNA hsa-miR-23b*:mirSVR_highEffct hsa-miR-23b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.77E-24 5.47E-20 2.47E-23 2.27E-22 65 405 "PLEKHH1,ADRA1D,C1QTNF3,MARCH3,CCAR2,BACH1,LINC00847,KSR1,CA4,ARHGEF2,CNTN1,SMARCAL1,CLIP3,CSF2RA,ERC2,UBXN2A,KIAA0753,SGSM2,EXOG,ECM2,ERBB2,CHST15,PSD2,NELFCD,CGREF1,OGA,HRASLS5,DISC1,PPARGC1A,WDFY3-AS2,GPER1,KAT7,AP4S1,PADI2,FRMD5,ZNF678,INSM1,MBD1,MBNL1,KCTD6,SCAMP5,NTRK3,PIK3C2A,SLC26A11,WDR25,FAT4,KHDRBS2,ZMAT4,KCNIP3,KCNIP1,ZNF430,SLC9A5,SLC11A1,ATF7IP,RCOR3,PDZRN3,SP2,JMJD6,SYN1,ENHO,TLR4,ERCC6L2,ZNF225,HPS4,SLC17A7" MicroRNA hsa-miR-1227:mirSVR_highEffct hsa-miR-1227:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.84E-24 5.50E-20 2.48E-23 2.28E-22 66 417 "NCKAP5,KLHL13,ADAM23,ADAM15,BMPR1B,C5,PTBP2,CLDN10,CLGN,QKI,LETMD1,ZNF521,SEC31B,RGS6,ERC2,CYBB,HDAC9,ARHGAP32,ZFYVE16,HEPH,SNAP91,PHC2,FRY,GOLGA7,EPHB1,GTF2IRD2,PSD2,BRSK1,NEURL4,DCLK2,GPD2,STMN2,GRIA2,GRM8,CLASRP,NEGR1,NKD1,KCNJ16,ZFYVE27,MBNL1,SRSF12,NF1,NUCB2,P2RX7,PCSK1,PPP2R5E,WBP1L,DPF2,RNASEL,CCDC82,GSTCD,KIRREL1,NCBP3,SEPHS1,NSFL1C,KLHL7,SYNE2,DOCK9,CHST5,UBE3A,FAM47E,PDSS2,DOCK8,ST7,JMJD1C,TRAM2-AS1" MicroRNA hsa-miR-325:mirSVR_highEffct hsa-miR-325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.84E-24 5.50E-20 2.48E-23 2.28E-22 66 417 "ACADM,KCTD16,TAOK1,ARNTL,RAB29,KALRN,CDH2,SULT4A1,MAGED1,SEC31B,CSNK1G3,PLXNA4,LIN54,RHOBTB1,DNAH9,DPYSL2,EDN1,MBNL2,STX2,SRRM1,CORO2B,ZSCAN30,EFCAB2,CELF1,STAU2,TUBGCP4,LNX1,TDRKH,SOX21,HAS2,HNMT,KCNN2,STXBP5,MAP2,MARK1,POC1B,ZNF680,NCF2,LOC100128398,PDE4D,GPR85,PFKFB3,ZFYVE21,FAM216A,PMP22,PRKAB2,GRAMD1C,HYDIN,GAL3ST4,RET,GTDC1,ATXN2,FHOD3,ARHGEF40,CDK5RAP2,TMCC1,NKAIN2,SYT1,ANKRD28,KLHL4,SATB2,PRR18,HIRA,RNF103,WNK3,RNF146" MicroRNA hsa-miR-661:mirSVR_highEffct hsa-miR-661:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-23 6.29E-20 2.83E-23 2.61E-22 72 492 "ASPHD1,AP2A2,PCDH10,LCORL,PHF12,APBA2,APC,SEMA4G,RGS20,NCOA1,RIPK1,ADAM23,LDB2,METTL6,LETMD1,CRYBB1,CSF2RA,SEC24C,GREB1,BOC,KIAA0753,SNAP91,FAM107B,DNM1,MED12,EPHB1,GMPR2,FGF11,SPECC1,USP21,TUBGCP4,MALT1,COPS8,GPD1,RNF165,CELF5,SOWAHA,IL6ST,ZNF678,KCNB1,KIF5A,LIMS1,PAXBP1,SMAD1,PIK3AP1,ADAM22,ZNF655,FAM218A,PPARA,DIRAS2,STK32A,RAD51D,RASGRF1,KLHL11,RIC8B,DGLUCY,SCP2,TNFRSF19,FAM214B,SLC11A1,RCOR3,BDP1,ATP10B,NKAIN2,CUX2,THRA,ENHO,FAM124A,TSN,TSC1,RPL7L1,CCDC136" MicroRNA hsa-miR-6890-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-23 6.35E-20 2.86E-23 2.63E-22 70 467 "CLK4,XKR4,ADCY5,MTA3,PHF12,CDC14B,PRX,INSYN2B,SLC2A11,BMP7,CFAP410,CAMK2G,DIS3L,RTTN,RNF14,HINFP,OSBPL3,UBXN2A,ZBTB24,SLC12A6,KRBA2,IRAK4,MRNIP,RGS17,TUBD1,SLC43A2,IGSF6,FGFR1,SEC23B,PCYOX1,APOPT1,PDLIM5,MSANTD4,DBF4,GLUL,KDM2B,RAB40B,LILRA2,DDX19B,ZNF546,NKD1,IL6R,IBA57,CYP27C1,LIMS1,GPR155,SAMD5,ZDHHC8,ZNF655,STRN3,EXOSC10,FITM2,APTX,MTMR10,NWD1,PGBD4,PEX26,ZNF430,ATF7IP,SMARCC2,BDP1,ZNF621,KLHL7,ALG1,TPCN2,PCDHA6,ZNF106,ARL10,ERCC6L2,FXR1" MicroRNA hsa-miR-567:PITA hsa-miR-567:PITA_TOP PITA 1.18E-23 6.62E-20 2.98E-23 2.74E-22 42 166 "ABHD6,ALCAM,EIF4G3,JAZF1,WASF1,LRBA,PUM1,SNAP91,PDCD6IP,EGR3,EIF4G2,EPB41L2,PSD2,SMAD1,MARK1,MBNL1,CHIC1,XRRA1,FAM98B,STRN3,LRP12,GDPD1,QRICH1,OXR1,CLIP1,SCN8A,FNIP1,HSPA4L,CCDC88A,CAMTA2,SS18,PRRC2C,TCF4,SYNE1,DICER1,ZBTB38,CADM2,EVI5,KCNAB1,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-634:PITA hsa-miR-634:PITA_TOP PITA 1.23E-23 6.89E-20 3.10E-23 2.85E-22 53 272 "ESYT2,ADRB2,OGT,SLC4A4,ATP2A2,CAMK2A,CAMK2G,NRXN3,RGS6,LRIG1,OSBPL3,LONRF1,GIT2,ALKBH8,RHOBTB1,PDCD6IP,ABCC5,YAF2,PLEKHA1,PAN3,ERBB4,AFF2,SYT3,LOXL3,GPD2,HMGCR,XRN1,LRP12,EPB41L4B,RASGEF1B,CNTLN,TMEM255A,SETD5,FBXW7,RTN1,SEMA6D,CPEB3,CNKSR2,PPP4R3A,BTBD3,SLC8A1,CPEB4,SOX11,LMO3,CLASP2,ERBIN,ADGRL3,TCF4,TSC1,FAM155A,TBC1D15,NAV3,DPF3" MicroRNA hsa-miR-149-5p:TargetScan hsa-miR-149-5p TargetScan 1.47E-23 8.20E-20 3.69E-23 3.39E-22 61 361 "ADD1,PCDH19,LTBP4,ATP2A2,NRP2,BID,FUBP1,CACNA1I,CABP7,CCNT1,NCOR1,RIMS4,CNTNAP2,JAKMIP2,KLHL3,RPS6KL1,FARSB,EDNRA,CNNM1,HEYL,EIF5,RGS17,FGF11,AMOTL2,DCTN2,RNPS1,GPT2,KAT7,NXPH3,NCKAP1L,HMGCR,C2orf72,KCNB1,KCNN3,KIF2A,KIF5A,GIT1,MSI1,NFIX,NNAT,NOVA2,PDE1B,BCAS3,RAD51D,GTDC1,PRIMA1,MYO18A,ATF7IP,FAM126B,IQSEC2,PHLDB1,ARC,C12orf76,CBX5,RASD2,ELP5,PLEKHH2,BCL2L13,POLR3H,INTS3,MSRB3" MicroRNA hsa-miR-302f:PITA hsa-miR-302f:PITA_TOP PITA 1.48E-23 8.25E-20 3.71E-23 3.41E-22 53 273 "FMNL2,USP31,HECW2,OSBPL1A,ALCAM,STX16,BCL7A,DST,THSD7A,CAMK2G,LRBA,CFL2,FOXN3,KIAA0408,HDAC4,DYNC1I1,SUGP2,TENM1,RGS17,AGAP2,C15orf41,AHDC1,TOX3,ADAMTS6,NEGR1,KIF5A,PACRG,ZC3H12B,NPTX1,PDE4D,GPR85,GNG2,ZFYVE21,PLEC,MAPKAP1,PPP2R2B,SNRK,PID1,ROBO2,SATB1,ATXN7,NLGN1,RCOR3,PDZRN3,SP2,NECAB1,PRRC2C,ADGRL3,KAT6B,NR2C2,UBE2H,CLDND1,SPHK2" MicroRNA hsa-miR-92b-3p:Functional MTI Functional MTI miRTarbase 1.58E-23 8.86E-20 3.98E-23 3.66E-22 88 709 "ABR,AP2A2,CASKIN1,FAM135A,ZSCAN18,ATP2A2,DOCK11,SYNJ1,FOXN3,TMEM184B,HECTD1,APPL1,EARS2,SPOCK2,GIT2,DBT,POM121,CPEB2,MRO,KMT5B,PLEKHA1,EIF1,DENND4A,DNAJC27,PRMT5,MEX3B,SLC37A3,GAA,BRD8,GLYR1,KIAA1958,PRRC2B,FUT10,LILRA2,TPPP,CIT,HMGCR,AGBL5,EID2B,ZIC5,RBPJ,IL6ST,LAMP2,PIK3AP1,MBNL1,MYO5A,CNOT4,PFKFB4,CCSER2,SNX10,ZFYVE21,XRN1,PURG,TATDN3,MTMR10,REV3L,SLC25A36,SETD5,TCP11L1,FNIP1,CPEB3,ZNF430,ATF7IP,CPEB4,SMARCC2,FAM126B,SOX11,KDM3A,UNC5B,MCF2L2,PBLD,ITPRID2,SUPT5H,MMS19,TACC1,DOCK9,NACC2,TRIO,TSC1,SGK3,ZNF17,ZNF24,MFF,EVI5,RNF103,PHTF2,FXR1,GAN" MicroRNA hsa-miR-526b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-23 9.07E-20 4.07E-23 3.75E-22 83 640 "FMNL2,FZD9,SORCS2,ZNF578,SEMA7A,ATP1B3,LDHD,ZBED1,DIS3L,CFL2,EPS15L1,QKI,ZNF385A,CPS1,ENTPD4,SOCS5,UBXN2A,DCAF8,DNAL1,YTHDC1,FBXL5,SLC12A6,DPYSL2,DNAJB6,FEM1B,KMT5B,IRAK4,CERCAM,TLR7,KATNAL1,ACSL4,GTF2IRD2,POLR1B,SUCO,TPK1,TRAF3IP2,C15orf41,KIAA1841,SRCAP,SESN1,CRCP,CBX1,LUZP2,FUT10,FICD,HAS2,KCNB1,GPR155,NBL1,CNOT4,PDPK1,PFKFB2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,CEP97,ZNF532,ATAT1,TMEM200C,HSPA4L,FAM126B,SP2,SP4,STAC2,GPRIN3,ZMAT3,NACC2,CBX5,PARD3,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,MPPE1,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-24:PITA hsa-miR-24:PITA_TOP PITA 1.67E-23 9.33E-20 4.19E-23 3.86E-22 48 223 "ADCY6,LRFN2,TAOK1,OGT,APBB2,RHBDL1,MAGI1,CNTFR,SNCAIP,RIMS2,RUBCN,MATR3,KLHL3,SLC12A6,FAM78B,APH1A,EGR3,SCML2,DLC1,FCGRT,AMOTL2,AFF2,SESN1,SPIN1,MCHR1,TMEM121B,RNF165,INPP5B,SFXN5,CHIC1,MEIS2,GIT1,MXI1,NEFM,NPTX1,PTPRD,GTDC1,TNFRSF19,POGZ,NEK4,SYP,SMG6,SZT2,TIAM1,MTMR14,FAM155A,MEIS3,ZXDA" MicroRNA hsa-miR-5698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-23 1.02E-19 4.59E-23 4.23E-22 72 496 "ABCF1,CLK4,XKR4,RNF157,ESYT2,HACE1,SORCS2,TAOK1,PPFIA3,PRX,DOCK11,CAMK2A,ISPD,METTL6,TMEM184B,AKAP5,CRMP1,DBT,KRBA2,HEYL,OPTN,EIF4G1,TUBD1,SEC23B,AFF2,SPECC1,CELF1,MSANTD4,PRRC2B,KAT7,IBA57,KCNH2,LIMS1,GPR155,CHST6,MKLN1,OLA1,ZNF655,CCSER2,PKM,GPSM2,DIRAS2,BDNF-AS,PRRT2,SETD5,PGBD4,SNX22,EMID1,NCBP3,HSPA4L,PEX26,PKNOX2,ANKRD36,FNBP1,ERC1,NFASC,MPRIP,KLHL7,ALG1,USP22,ZNF106,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR,AGMO,ZNF74,ZNF154,TIGD6,RNF170" MicroRNA hsa-miR-424-5p:Functional MTI Functional MTI miRTarbase 1.88E-23 1.05E-19 4.71E-23 4.34E-22 70 471 "AXIN2,FZD9,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,APBB2,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,CA8,RUNX1T1,CCNT1,SOCS6,MAGED1,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,SACS,DMPK,DMTF1,FCF1,HEYL,EIF4G2,PLEKHA1,ZNF391,ANKMY1,ZNF585B,FGFR1,MSANTD4,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,CHIC1,MYO5A,OCRL,PDE4D,PIK3R1,PSAT1,PTCH1,ANKHD1,PTPRD,RBBP6,ZFHX4,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,ZMAT3,TPM2,TUBB2A,UBE2H,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-216b-5p:TargetScan hsa-miR-216b-5p TargetScan 1.91E-23 1.07E-19 4.79E-23 4.41E-22 52 264 "CLK4,BRAP,PTCHD1,HACE1,PKP4,CASK,RUNX1T1,DGKI,DCLK1,CLGN,CFL2,NSL1,CRY2,ABCG1,LRIG1,DZIP3,FAM131B,GUCD1,CPEB2,PDCD6IP,EBF1,ENPP6,FGF12,FGFR1,ANKFY1,GAD1,BTN2A1,FRMD5,HLF,HNF4G,NEGR1,KCNJ5,LSAMP,SAMD5,HS6ST3,NFYA,PAX6,SDK2,PRKAB2,IQSEC3,RFX3,RXRA,HSPA4L,SCAF8,FNDC3A,CPEB4,CXXC4,MBD5,CMTR2,FAM126B,CUX2,C18orf54" MicroRNA hsa-miR-200c-3p:Functional MTI Functional MTI miRTarbase 1.93E-23 1.08E-19 4.84E-23 4.45E-22 47 214 "TXNDC16,CDC14B,ARHGDIA,STX16,JAZF1,SEPT7,NOG,CFL2,QKI,BAG4,PHF14,RASSF2,MAMLD1,DNAJB6,EDNRA,ACSL4,TUBB3,DLC1,FLT1,CELF1,SESN1,MALT1,RASSF8,TJAP1,LRP1B,NTRK2,PDPK1,PKD1,MAPK7,PTPN13,PTPRD,ZFHX4,WDR37,ELMO2,RCOR3,MBD5,KIF13A,ZNF621,ERBIN,ZEB1,USP22,SIRT1,ZFPM2,ZMAT3,TRPS1,TUBB2A,WIPF1" MicroRNA hsa-miR-4419b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-23 1.16E-19 5.17E-23 4.76E-22 72 497 "ABCF1,NDRG3,TXNDC16,APAF1,AQP6,CDC14B,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,SLC35F1,CLOCK,IPCEF1,UBXN2A,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,CDK19,MCF2L2,LHPP,FAM208A,SLC19A3,PCDHA6,SSBP2,EVI5,URM1,MPPE1" MicroRNA hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 2.09E-23 1.17E-19 5.24E-23 4.82E-22 50 244 "C3orf14,KCTD16,PCDH10,IGDCC4,DOCK11,MTMR3,CAMK2B,CAMK2G,LRRFIP1,DLGAP2,NCOR2,RIMS2,HDAC4,MTSS1L,CEP85L,FLT1,ANKFY1,CHL1,LYVE1,RNF165,BACH2,KPNA5,SAMD14,NFIX,CNOT4,PDE4A,PURG,ELOVL2,DPF2,FIGN,KCTD17,RORB,MCMBP,CSRNP3,ATXN2,ATXN7,CCDC88A,MAPKBP1,MBD5,NFASC,CLASP2,ANKRD12,CBX5,CSMD1,KAT6B,NR2C2,FLRT2,KLC2,POLR3H,CADM2" MicroRNA hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 2.09E-23 1.17E-19 5.24E-23 4.82E-22 50 244 "C3orf14,KCTD16,PCDH10,IGDCC4,DOCK11,MTMR3,CAMK2B,CAMK2G,LRRFIP1,DLGAP2,NCOR2,RIMS2,HDAC4,MTSS1L,CEP85L,FLT1,ANKFY1,CHL1,LYVE1,RNF165,BACH2,KPNA5,SAMD14,NFIX,CNOT4,PDE4A,PURG,ELOVL2,DPF2,FIGN,KCTD17,RORB,MCMBP,CSRNP3,ATXN2,ATXN7,CCDC88A,MAPKBP1,MBD5,NFASC,CLASP2,ANKRD12,CBX5,CSMD1,KAT6B,NR2C2,FLRT2,KLC2,POLR3H,CADM2" MicroRNA hsa-miR-371a-5p:TargetScan hsa-miR-371a-5p TargetScan 2.11E-23 1.18E-19 5.28E-23 4.86E-22 53 275 "RNF150,HACE1,PKP4,ATP2B2,PTBP2,CAMK2G,KRIT1,C1orf52,CFL2,COL9A1,AATK,CCDC144A,DGKG,SCRN1,DNAL1,FAM107B,DNAH9,FARSB,GOLGA7,CALCRL,RCAN2,ETV1,CELF1,PCDH17,MALT1,GPR75,PRRC2B,GPD2,KAT7,BVES,NEGR1,MMP16,MN1,MYCN,NOVA2,PCDH8,APTX,GTDC1,RPS6KA2,CSRNP3,R3HDM2,PKNOX2,CPEB4,KDM3A,MYCBP2,CLSTN2,NECAB1,GPRIN3,ANKS1B,CADM2,HNRNPA3,MSRB3,NETO1" MicroRNA "AAGCAAT,MIR-137:MSigDB" "AAGCAAT,MIR-137:MSigDB" MSigDB 2.17E-23 1.22E-19 5.44E-23 5.01E-22 46 205 "ABHD6,FMNL2,OGT,CADPS,STX16,ARHGEF7,CACNA1G,QKI,ZNF385A,RIMS4,RHOBTB1,SLC43A2,ERBB4,C15orf41,PPARGC1A,ATOH8,BACH2,HLF,MEIS2,MITF,MMP16,MSI1,NOVA1,PDE4A,PLEC,PPP5C,SNRK,NKAIN1,OXR1,MORC4,RORB,SATB1,PPM1E,FNDC3A,LIMCH1,SOX11,NFASC,PLCB1,SYT1,ANKRD12,RPGRIP1L,RELL2,UBE2H,FLRT2,MGAT5B,SPHK2" MicroRNA hsa-miR-204-5p:Functional MTI Functional MTI miRTarbase 2.22E-23 1.24E-19 5.55E-23 5.11E-22 64 399 "AS3MT,XKR4,ADCY5,MTA3,SORCS2,AK2,SPOP,SEMA4G,ARSE,ASGR1,BCL7A,BID,MYRF,LURAP1,CAMK2G,CDH2,SEC31B,PLCXD3,CYBB,ELMSAN1,CHRDL1,FEM1B,SLC43A2,AMOTL2,ANKFY1,SRCAP,RAB40B,TPPP,PTPRT,HAS2,PADI2,BACH2,MIER3,EID2B,JAK2,LSAMP,MBNL1,MEIS1,MEIS2,XRRA1,SAMD5,MX1,NPTX1,NTRK2,KANSL1,MARCH1,CEP97,USP47,DPF2,GTDC1,RORB,ELP2,ATXN7,GALNT10,MYO18A,ZBTB43,IQCE,TCF4,TCF12,SIRT1,WNK3,ZDHHC20,DPF3,GAN" MicroRNA hsa-miR-873-5p.2:TargetScan hsa-miR-873-5p.2 TargetScan 2.29E-23 1.28E-19 5.72E-23 5.26E-22 61 364 "ADCY6,KIAA1211,RNF150,OGT,MARK4,CCDC74A,BCL7A,LURAP1,DGKI,NRXN3,LETMD1,RIMS4,PITPNM3,MYADM,MATR3,IST1,DGKG,SCRN1,MYEF2,KLHL3,CELSR3,EZH1,FGF1,FHL1,ANKFY1,FAM49B,CELF1,C15orf41,CPLX1,PCDH17,KAT7,NCKAP1L,DDX19B,HLF,NKD1,KCNB1,LIFR,MBD1,CHIC1,MEF2C,MXI1,NFIX,NOVA1,GPR137C,PCSK5,KANSL1,CEP41,DIRAS2,NDUFS7,RAD51D,RORB,HSPA4L,MYO18A,FBXO11,HECW1,PEG10,FBXW11,GPRIN3,MFF,GDPD5,NHSL1" MicroRNA hsa-miR-4478:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-23 1.30E-19 5.81E-23 5.35E-22 72 498 "ABCF1,NDRG3,TXNDC16,APAF1,AQP6,CDC14B,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,SLC35F1,CLOCK,IPCEF1,UBXN2A,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,CDK19,MCF2L2,LHPP,FAM208A,SLC19A3,PCDHA6,SSBP2,EVI5,URM1,MPPE1" MicroRNA hsa-miR-3929:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-23 1.30E-19 5.81E-23 5.35E-22 72 498 "ABCF1,NDRG3,TXNDC16,APAF1,AQP6,CDC14B,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,SLC35F1,CLOCK,IPCEF1,UBXN2A,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,CDK19,MCF2L2,LHPP,FAM208A,SLC19A3,PCDHA6,SSBP2,EVI5,URM1,MPPE1" MicroRNA hsa-miR-518b:mirSVR_lowEffct hsa-miR-518b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-23 1.30E-19 5.81E-23 5.35E-22 72 498 "NDRG3,PSMG3-AS1,RNF150,OLMALINC,KLHL13,ASGR1,FUBP1,THSD7A,PRC1,CCPG1,SRSF11,SOCS6,QKI,SULT4A1,MAP4K4,ARHGEF6,MYRIP,ZNF521,ANKRD44,DAPK1,DGCR5,RHOBTB1,ZNF582-AS1,DMPK,SLC29A4,CDON,EDN1,SEMA3D,EIF1,IP6K2,NELFCD,SDCBP2,TUBA8,PCLO,AGBL5,SYTL4,LYRM9,MYO6,RTL5,NME4,OPA1,PFKFB2,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,SLC25A36,CCDC25,FBXW7,SCN2B,CPEB4,MAPKBP1,PDZRN3,KDM3A,ADHFE1,AGTPBP1,MGRN1,ZEB1,ZMAT3,RIMBP2,TRIO,TSC1,UCHL1,CELF4,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-10b:mirSVR_highEffct hsa-miR-10b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.37E-23 1.33E-19 5.92E-23 5.45E-22 77 563 "KIAA1211,ALCAM,LTBP4,CCDC146,UPRT,IGDCC4,DOCK11,SGCE,NFS1,CNTFR,CNTN1,ABI3BP,SLC35F1,NCOR2,RIMS2,GAPVD1,KIAA0753,DDX46,E2F5,EDN3,FCF1,YAF2,PHF20L1,EGFR,EIF1,SCML2,RACK1,CEP78,UFM1,GAD1,C1QL4,RNF165,ZHX1,HMGCR,SMAP1,LIMS1,EFHB,AFDN,MYO9A,CNOT4,SLC10A4,XRN1,FAM216A,PURG,LRP12,EPB41L4B,TATDN3,VPS13C,ELOVL2,ERI2,FIGN,RPE,STK32B,SCP2,SEC14L1,ZFP30,CCDC88A,ZNF667,PDZD2,DOK5,POGZ,NXT2,PRRC2C,TRIM2,SYNE1,PUM2,FAM200B,TIAM1,DCBLD1,LYPD6,ZNF154,FSTL5,ZNF189,SLC30A4,NAV3,WNK3,PDSS2" MicroRNA hsa-miR-592:PITA hsa-miR-592:PITA_TOP PITA 2.38E-23 1.33E-19 5.93E-23 5.46E-22 45 196 "ZFYVE28,STX16,THSD7A,SPAG9,NRXN3,QKI,AKAP6,PLCXD3,LONRF1,FOXO3,CPLX2,PCDH17,HLF,NEGR1,TCEAL6,KCND2,LRP1B,MOV10,MYCN,NOVA1,NPTX1,PCDH9,PDE4D,OLA1,PTPRD,SUSD4,GTDC1,SH3GL3,PPP4R3A,SLC8A1,RCOR3,SNAP25,FAM126B,SP2,LMO3,KANK1,PRRC2C,ARHGEF9,ANKRD28,ADGRL3,TIAM1,MTMR14,KCNT2,WNK3,HNRNPA3" MicroRNA hsa-miR-1288:mirSVR_highEffct hsa-miR-1288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.62E-23 1.47E-19 6.54E-23 6.02E-22 59 342 "NDRG3,PTCHD1,INTS2,KIAA1324,CADPS,NPIPA1,PPT2,CLCN3,ARHGEF6,FAM149A,LETMD1,CREM,HAPLN1,VCAN,HEPH,ELMO1,KIF19,DTNA,KRBA2,EGFR,PLEKHA1,SIRPB1,FAM198B,CORO2B,CHST15,SLC9B2,OLFM1,FGF13,JKAMP,ATP2C1,MEGF11,FAM120B,LRRC37A6P,TDRKH,ZNF496,HNMT,ZNF546,ZNF678,LAMP2,BEX5,PDCD2,PRIMPOL,VPS13C,CASTOR1,TMEM231,PBRM1,ATP8B4,FBXO11,SLC2A5,SULF2,ANKRD28,RNF216P1,SYNPO2,TRIM9,SLC30A3,ADAMTS9,KAT6A,TIGD6,FXR1" MicroRNA hsa-miR-377-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.75E-23 1.54E-19 6.86E-23 6.31E-22 52 266 "TMEM132B,INTS2,KCTD16,CADPS,ALDH7A1,JAZF1,CACNA1B,CRLF1,STOML1,CLTC,NRG2,CENPL,EDIL3,SNX29,EGR3,SLC43A2,HSPA12B,FOXF2,NBEA,SPECC1,MSANTD4,SESN1,TPPP,FRMD3,HLF,USP51,C2orf72,TJAP1,IBA57,LAMP2,PDE3A,PFKFB2,DUSP26,PKD1,APTX,ROBO1,HUNK,SCN8A,CPEB3,CPEB4,PDZD2,TRERF1,MYCBP2,SEPT3,SYT5,TAL1,BHLHB9,ZNF610,UBE2H,ZNF781,CRB2,ZNF195" MicroRNA "TGCAAAC,MIR-452:MSigDB" "TGCAAAC,MIR-452:MSigDB" MSigDB 2.96E-23 1.66E-19 7.37E-23 6.78E-22 34 105 "SYN3,UNC5A,DOC2A,LRCH2,CHRD,ATP2B2,NRP2,SEPT7,DBT,DMD,EPHB1,AFF2,ATP2C1,GGT7,RNF165,STMN1,MBNL1,MMP16,PCDH8,PCDH9,SEPT4,PPP2R5E,CNTLN,SALL1,SCN8A,CHD9,TRIM67,IQSEC2,NKAIN2,RPGRIP1L,DOCK9,TRPS1,ZIC1,MFF" MicroRNA hsa-miR-616:PITA hsa-miR-616:PITA_TOP PITA 3.20E-23 1.79E-19 7.96E-23 7.33E-22 38 136 "ABHD6,ADD1,AXIN2,PTCHD1,TAOK1,TMEFF1,ZFYVE28,CHGB,PLCXD3,RIMS2,FAM131B,YTHDC1,WDR20,EPB41L2,EPHB1,FAM49B,STON1,FAM19A2,ADAMTS6,BACH2,MIER3,SYNPO,MAT2A,MBNL1,MEIS1,PDE4D,PMP22,MAPK10,CCDC112,SGK1,MYO18A,DZIP1,RBM26,SS18,ARHGEF9,PLCB1,TRIM2,RPGRIP1L" MicroRNA hsa-miR-6849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-23 1.88E-19 8.37E-23 7.70E-22 89 731 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,DOCK11,AP1M1,ISPD,CBS,CCNT1,SLC16A4,NRXN3,SUSD5,PPP1R16B,UBXN2A,CTH,GREB1,USP6NL,RASSF2,TMEM170A,DNAL1,YTHDC1,MTX3,TOM1,EBI3,MRO,APC2,ANKMY1,ZNF589,ANKFY1,TRMO,CELF1,ZNF44,B4GALNT1,ZNF234,SRCAP,CRCP,GPR75,GLUL,LUZP2,LILRA2,DDX19B,AGBL5,KIF5A,LAMP2,CHST6,MMP17,LAYN,ZC3H12B,SFR1,SLC11A2,CCSER2,MTRF1L,STK32A,PTPRB,TMEM145,PEX2,ZNF844,CEP97,KLHL11,KLHDC8A,SNX22,NCBP3,ZNF331,CSRNP3,HSPA4L,PREX2,SEPHS1,RADIL,ANKRD36,FAM126B,MCF2L2,SSTR2,NEK4,SLC37A2,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,TRIM16L,AP3B2,GAN" MicroRNA hsa-miR-130b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-23 1.99E-19 8.86E-23 8.15E-22 59 344 "AS3MT,GALNT13,CDC42BPA,USP37,PCDHGB4,PROM1,SPAG9,CD86,LRRFIP1,CRY2,NCOR2,RGS6,RIMS4,CST3,DZIP3,PITPNM3,MAML1,ZC3H11A,CDON,RCAN1,RGS17,EMX2,NRN1,FGF1,RAPGEF6,SRCAP,SULT1C4,SYNPO,IGF1,ZIC5,GPR155,MID1,P2RX7,PDE3A,PLCL1,PPARA,KANSL1,PRKCB,PIGG,ZSCAN2,ZNF793,TMLHE,ALG9,SPIN3,CSRNP3,ATXN7,OGDHL,RBM26,NSFL1C,ANKRD28,EXOC7,TNS1,TTC3,TBC1D15,ZBTB38,DPYSL5,MEIS3,SLC30A3,FRMD6" MicroRNA hsa-miR-28-5p:mirSVR_highEffct hsa-miR-28-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.68E-23 2.06E-19 9.13E-23 8.41E-22 83 648 "ACADM,ACHE,AS3MT,RNF150,HACE1,BEGAIN,AMPH,ZFAT,OGT,SEMA4G,ASPA,CACNA1G,PTBP2,ZBED1,SRSF11,CNTFR,PREPL,GDA,SNCAIP,OSBPL3,FAM169A,RIMS2,GAPVD1,TMEM170A,GIT2,SV2B,DLX1,ABCC5,YAF2,FGF1,NSG1,DLL3,AP4B1,MTHFD2,NEU3,GPD2,GRIA2,PLCD4,ADAMTS13,GSTT2,ATXN2L,KIF5A,MAT2A,MEST,NFE2L2,DNHD1,ZNF655,SAMD9,PIGG,TMEM260,ZIK1,C1orf109,ZNF615,MARCH1,FAT4,MSANTD2,RDX,NUDT11,GSTCD,YY1AP1,ARMH4,LRRK2,CASC3,SEC31A,ABLIM3,EPN2,PKNOX2,SIRT2,ZFP1,MAST1,SNAP25,MYO16,RGL1,ADHFE1,DMXL2,TMEM9,ELP5,ANKS1B,DHX33,KAT6A,PHTF2,JMJD1C,NLRP3" MicroRNA hsa-miR-196a:PITA hsa-miR-196a:PITA_TOP PITA 3.72E-23 2.08E-19 9.23E-23 8.50E-22 45 198 "USP31,PCDH19,DOC2A,LCORL,MAP4K3,GAS7,CASK,CHRD,CALM1,PTBP2,FAM19A5,PCYT1B,TBPL1,RGS6,PPP1R16B,PPP6R2,SNAP91,RASGRP1,MBNL2,EPB41L2,GALC,C15orf41,TOX3,CNTRL,DDX19B,LRP1B,SCHIP1,MINDY2,RDX,ATP8B4,FNIP1,WDR37,TRERF1,SOX11,PEG10,RBM26,LARP4,MTCL1,PUM2,DICER1,NR2C2,TSC1,VSNL1,SOCS4,GAN" MicroRNA hsa-miR-196b:PITA hsa-miR-196b:PITA_TOP PITA 3.72E-23 2.08E-19 9.23E-23 8.50E-22 45 198 "USP31,PCDH19,DOC2A,LCORL,MAP4K3,GAS7,CASK,CHRD,CALM1,PTBP2,FAM19A5,PCYT1B,TBPL1,RGS6,PPP1R16B,PPP6R2,SNAP91,RASGRP1,MBNL2,EPB41L2,GALC,C15orf41,TOX3,CNTRL,DDX19B,LRP1B,SCHIP1,MINDY2,RDX,ATP8B4,FNIP1,WDR37,TRERF1,SOX11,PEG10,RBM26,LARP4,MTCL1,PUM2,DICER1,NR2C2,TSC1,VSNL1,SOCS4,GAN" MicroRNA hsa-miR-3139:mirSVR_highEffct hsa-miR-3139:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.80E-23 2.12E-19 9.42E-23 8.67E-22 85 676 "ACADM,ACHE,AS3MT,ACTN1,RNF150,HACE1,BEGAIN,AMPH,ZFAT,OGT,DDO,SEMA4G,LINC00173,ASPA,CACNA1G,C5,ZBED1,SRSF11,CNTFR,PREPL,GDA,SNCAIP,OSBPL3,SUSD5,PDE4DIP,FAM169A,GAPVD1,TMEM170A,GIT2,SV2B,ABCC5,F8,FGF1,NSG1,DLL3,STAU2,AP4B1,NEU3,GRIA2,PLCD4,ADAMTS13,GSTT2,KIF5A,MAT2A,MEST,ADAM22,LYRM9,NFE2L2,DNHD1,ZNF655,MAPKAP1,TMEM260,ZIK1,C1orf109,ZNF615,MARCH1,MSANTD2,RDX,PRRT2,NUDT11,GSTCD,YY1AP1,LRRK2,CASC3,SEC31A,EPN2,PKNOX2,SIRT2,SLC22A4,ZFP1,MAST1,SNAP25,MYO16,TTBK2,RGL1,ADHFE1,DMXL2,TMEM9,PLEKHH2,CCDC14,DHX33,ST7,KAT6A,JMJD1C,NLRP3" MicroRNA hsa-miR-30d-5p:Functional MTI Functional MTI miRTarbase 4.11E-23 2.30E-19 1.02E-22 9.39E-22 61 368 "TAOK1,SEMA6A,MARCH4,PCDH10,USP37,ATP1A1,STX16,ATP2A2,DPY19L3,ST3GAL5,MAP4K4,TBPL1,BAG4,PREPL,CREM,SACS,FEM1B,CELSR3,MRO,ASB3,DCTN4,EPB41,SCML2,CHST15,FKTN,CELF1,MSANTD4,HHIPL1,IP6K3,MTHFD2,DBF4,TNRC6A,MIER3,ELOVL5,LIFR,LIMS1,SMAD1,LYPLAL1,REV3L,PBRM1,SETD5,ALG9,PCMTD2,SBF1,FNIP1,PPP4R3A,BTBD7,CPEB4,KDM3A,SP4,PEG10,STAU1,ZSCAN29,SLC35G2,NACC2,XPO1,MKRN3,POLR3H,ZFAND5,PHTF2,ZDHHC20" MicroRNA hsa-miR-593:PITA hsa-miR-593:PITA_TOP PITA 4.16E-23 2.33E-19 1.03E-22 9.48E-22 46 208 "ELFN2,ZNF608,PCDH19,DPP10,DYNLL1,NRP2,THSD7A,NOG,HECTD1,NRG2,EGR3,RGS17,PAN3,EYA1,FGF11,AGAP3,FOXO3,USP21,ST6GALNAC3,GABRB3,CPLX2,GPD2,NKD1,LRRTM1,MEF2C,BLOC1S2,NTRK3,KSR2,ZNF827,CDK18,SETD5,KCNIP1,SCAF8,CHD9,WDR37,WDR47,MBD5,ERBIN,CAMTA1,TCF4,SATB2,TCF12,FRYL,NR2C2,KCNE5,KAT6A" MicroRNA hsa-miR-4253:mirSVR_highEffct hsa-miR-4253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.47E-23 2.50E-19 1.11E-22 1.02E-21 70 478 "KLHL32,KIAA1211,CARNS1,LTBP4,BEGAIN,PKP4,CADPS,STK33,ATP6V1G2,CFLAR,IL33,CACNA1B,CBS,CLDN10,ARHGAP33,PREPL,RGS6,CCDC144A,RIPOR2,ARHGAP24,SPATA2,DNM1,RPS6KL1,KMT5B,EIF4G2,CLVS1,GORAB,FAM120B,GCK,TDRKH,SLC2A6,FRMD5,ARHGAP36,MIER3,HNF4G,MEIS2,NPTX2,NTRK2,NTRK3,POLR2F,CEP41,HYDIN,APTX,LGI2,C12orf49,ATP8B4,CSRNP3,AMBRA1,SLC4A3,PEX26,ZSWIM8,UHRF1BP1L,MYCBP2,KDM4C,ZC3H13,ZBTB43,NKAIN2,NUDT10,TACC1,SATB2,ASXL3,RASD2,TPM2,SMUG1,UBE2H,UGT8,XPO1,ZIC2,TRAM2-AS1,KLHDC1" MicroRNA hsa-miR-127-5p:PITA hsa-miR-127-5p:PITA_TOP PITA 4.50E-23 2.52E-19 1.11E-22 1.03E-21 50 248 "ADRB2,KLHL13,STX16,CAMK2G,SRSF11,FOXN3,CNR1,ARMC8,GAPVD1,ARHGAP24,DMD,CASP8AP2,HIPK3,MBNL2,ENPP6,ETV1,FUT9,OGA,PCDH17,PPARGC1A,MAP7D2,LOXL3,INSM1,MAN2A2,MEIS2,NCAM2,NEFM,NEK1,PIK3R1,POLG,KANSL1,TMEM104,PTCH1,OXR1,GTDC1,SATB1,CPEB3,SLC8A1,RCOR3,SP4,POGZ,RGL1,ANKRD28,RPGRIP1L,ZFPM2,CADM2,RGS7BP,HNRNPA3,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-103a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.51E-23 2.52E-19 1.12E-22 1.03E-21 68 453 "SYS1,AXIN2,AP2A1,SEMA6A,OGT,STK33,ZBTB10,NUMB,DOCK11,DST,SYNJ1,MTMR3,CA12,RUNX1T1,CCNT1,TBPL1,OSBPL3,CSNK1G3,VCAN,PPP1R16B,TMEM170A,DAPK1,YTHDC1,JAKMIP2,DMPK,CPEB2,DMTF1,GOLT1B,FCF1,YAF2,PLEKHA1,KATNAL1,ZNF585B,ANKFY1,CAMKK2,GPD1,ZHX1,AGFG1,IDH3A,KIF5A,LAMP2,MAP4,ZNF680,MYCN,MYO5A,PDE4D,ENPP2,PIK3R1,PRKAB2,CNNM2,TMEM255A,RBBP6,EXD2,FBXW7,CLIP1,SALL1,CPEB3,EPC1,TMCC1,DNAJC9,CYB561A3,DICER1,NACC2,SLC35A4,ZBTB38,DHX33,ITM2C,PLSCR4" MicroRNA hsa-miR-2114*:mirSVR_highEffct hsa-miR-2114*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.91E-23 2.75E-19 1.21E-22 1.12E-21 66 429 "AXIN2,ZNF578,DPP10,BCAS1,NUMB,ATP2A2,BCL7A,CARS,P2RX6,CBFA2T2,CD38,LARGE1,DIS3L,CHRNA4,FAM171B,CS,DOCK4,ARMCX4,PITPNC1,MYEF2,POM121,DLX1,GRIN3A,HS3ST2,ECM2,APH1A,EGFR,IRAK4,FCGR1A,MEGF11,RAPGEF6,TMEM8B,TNRC6A,TDRKH,LILRA2,ZNF496,ZBTB49,MIER3,CELF5,MYLK2,KCNN2,MEF2C,RTL5,NDP,NUCB2,CDK18,HYDIN,MASP1,APTX,QRICH1,PBRM1,RNASEL,CARF,ATAT1,ABLIM3,ELMO2,LIMCH1,KDM4B,ZSCAN29,PCDHGA11,TPM1,TRO,KCNE5,OSBP2,RICTOR,AMN1" MicroRNA hsa-miR-598:mirSVR_highEffct hsa-miR-598:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-23 2.87E-19 1.27E-22 1.17E-21 51 259 "ASPHD1,KDM5D,ADD1,CCDC146,ATP2A2,ZMYM4,CHGB,NDST3,AKAP7,SLC4A8,ZFP28,CNRIP1,NECTIN3,CNTNAP2,USP6NL,CLVS1,CEP78,MED12L,C15orf41,ALDH1L1,TOX3,ZNF678,KCND2,CYP27C1,MAP6,MITF,MN1,GPR137C,SLC26A11,OXR1,ZDHHC14,CCDC82,FBXW7,SH3GL3,KIF16B,NLGN1,IFT122,SNCA,SNRPN,SPTB,VPS13A,MCF2L,TIAM1,PPIL6,DCBLD1,RUSC1,TSN,PLEKHH2,SPIRE1,CADM2,MSRB3" MicroRNA hsa-miR-3130-3p:mirSVR_highEffct hsa-miR-3130-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.38E-23 3.01E-19 1.33E-22 1.23E-21 67 442 "XKR4,FMNL2,KIAA1324,C1QTNF3,SUGT1P4-STRA6LP-CCDC180,PHYHD1,CACNA1G,CBR1,CD38,RAB33A,QKI,HECTD1,SLC35F1,FAM171B,DCAF8,LONRF1,MATR3,PLPPR4,SGSM2,DYNC1I1,EDN1,ELN,HSD17B14,ZNF549,FCGRT,PRMT5,WDR83,HVCN1,MSTN,CLASRP,GSTT2,HMGCL,ZDHHC15,IRF8,LAMP2,STMN1,PAXBP1,MEIS1,KCTD6,CCDC13,NELL2,PDCD2,PLCB2,NECAB2,POLG,ZCWPW1,ELP2,RPL15,FBXW7,ABCA11P,TRA2B,RASA3,ATF7IP,SMARCA4,LIMCH1,SYN2,PCDHB9,MTMR14,ERCC6L2,RUSC1,RPL7L1,BCL2L13,MGAT5B,PROCA1,PHTF2,RNF170,IFT88" MicroRNA hsa-miR-4306:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.43E-23 3.04E-19 1.34E-22 1.24E-21 50 249 "ADD2,CASKIN1,HACE1,TAOK1,PDZD4,SFMBT2,IGDCC4,BACH1,EPS15L1,ARHGEF6,ZNF385A,CSF1,CSNK1E,CNTNAP2,SLITRK5,TM9SF4,IP6K1,SPATA2,ZC3H11A,CHRDL1,ABCC5,E2F6,FGFR1,AMOTL2,AFF2,CELF1,SRCAP,TNRC6A,KAT7,SLC6A17,ZFYVE27,ZC3H12B,GPR137C,PDE4A,PFKFB3,PKD1,PKM,PLCD1,PRRT2,MORC4,HSD11B1L,MRAS,BTBD3,PKNOX2,CCDC88A,IQSEC2,TMEM9,SLC38A1,SIGLEC10,ITM2C" MicroRNA "AAGCACT,MIR-520F:MSigDB" "AAGCACT,MIR-520F:MSigDB" MSigDB 5.48E-23 3.06E-19 1.35E-22 1.25E-21 47 219 "ABR,MTUS1,OSBPL8,AK2,ATP2B2,MTMR3,JAZF1,MYRF,PRC1,CDC25B,CDH2,CFL2,LETMD1,ZNF385A,RASSF2,EDNRB,TMTC1,MBNL2,KMT5B,PAN3,EMX2,MED12L,FLT1,BACH2,IL6ST,MEF2C,NOVA1,OCRL,PRKACB,RDX,FIGN,RIC8B,FNDC3A,WDR37,TET1,IQSEC2,CDK19,LMO3,RGL1,ARHGEF9,FBXW11,ZFPM2,NR2C2,VLDLR,RICTOR,PRDM8,FAM13C" MicroRNA hsa-miR-30e-5p:Functional MTI Functional MTI miRTarbase 5.61E-23 3.14E-19 1.39E-22 1.28E-21 59 347 "TAOK1,SEMA6A,MARCH4,PCDH10,USP37,STX16,ATP2A2,DPY19L3,ST3GAL5,SOCS6,TBPL1,BAG4,PREPL,CREM,SACS,CELSR3,MRO,MBNL2,ASB3,DCTN4,VPS13B,EPB41,SCML2,CHST15,CELF1,MSANTD4,HHIPL1,IP6K3,MTHFD2,DBF4,TNRC6A,MIER3,ELOVL5,LIFR,LYPLAL1,MBNL1,PSMA6,MSANTD2,REV3L,PBRM1,SETD5,ALG9,PCMTD2,SBF1,BTBD7,CPEB4,LIMCH1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,SLC35G2,NACC2,XPO1,MKRN3,ZFAND5,PHTF2,ZDHHC20" MicroRNA hsa-miR-193b-3p:Functional MTI Functional MTI miRTarbase 5.68E-23 3.18E-19 1.40E-22 1.29E-21 97 853 "ACTN1,ESYT2,HACE1,NT5C3B,ATP1A1,STX16,ALDH7A1,BARD1,BLM,C5,SPAG9,CBS,KYAT1,ARHGAP33,C2CD2,CS,DLX1,DPH1,FARSB,E2F6,TMTC1,PLXNC1,ASB3,EIF1,COQ7,GMPR2,TUBA1B,TUBB3,TAOK3,FGF11,TMEM164,ANKFY1,NSG1,KIAA1841,AHDC1,TXNL4A,CBX1,PRRC2B,CACFD1,PSIP1,ATOH8,PACSIN2,HMGCR,HSPA1L,GAREM2,ITPKA,SLC35G1,KIT,STMN1,ZFYVE27,MAT2A,DBNL,MYO5A,HNRNPM,NF1,NME4,NUCB2,EXOSC10,CEP41,EPDR1,SNRK,PTPRG,MSANTD2,MORC4,UBR7,C12orf49,RMI1,CASC3,MYO18A,SHMT2,SEC31A,DHX30,SEPHS1,ELMO2,UNC5B,PEG10,ZBTB43,SULF2,SYNE2,DNAJC9,TACC1,ZMAT3,MTMR14,LRRC8A,NEIL2,AMACR,RUSC1,TSC1,RPL7L1,UCHL1,XPO1,CIAPIN1,TRIM16L,KAT6A,NLRP3,AAAS,RNF146" MicroRNA hsa-miR-301a-3p:Functional MTI Functional MTI miRTarbase 6.66E-23 3.73E-19 1.64E-22 1.51E-21 63 395 "TAOK1,ABCD2,PHF12,STX16,CFL2,CLCN3,TPP1,QKI,LONRF1,DAPK1,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PTPRG,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SSTR2,ERBIN,ATMIN,SATB2,DICER1,GPR161,ZMAT3,THRA,NACC2,UBC,ZNF711,ZNF24,ZNF154,MFF,WNK3,FXR1" MicroRNA hsa-miR-342-3p:TargetScan hsa-miR-342-3p TargetScan 6.87E-23 3.84E-19 1.69E-22 1.56E-21 48 230 "PPFIA4,APBB2,CA12,P2RX6,CFL2,PLAA,SEC31B,CSF1,DNM1,EDNRA,FLNC,NBEA,CAMKK2,CELF1,PCDH17,GPR75,GRIN2D,BTN2A1,KAT7,FAM222A,FRMD3,AGFG1,METTL21A,IPO5,NCOA7,LSAMP,AFF1,MSI1,PPP2R5E,CNNM2,PTPRN2,FIGN,RFX3,RGS4,PRIMA1,HUNK,FAM192A,EPN2,BTBD7,EPC1,FAM126B,MMS19,FAM208A,PDLIM2,CUX2,NSD1,CBX5,PLEKHH2" MicroRNA hsa-miR-212-5p:TargetScan hsa-miR-212-5p TargetScan 7.28E-23 4.07E-19 1.80E-22 1.65E-21 57 326 "PITPNM2,PKP4,BID,LDHD,LDLRAD4,DDR1,CALM1,CFL2,NRG2,CSNK1E,PPP1R16B,APPL1,MAML1,RCAN1,HEYL,EGR3,MRVI1,GABBR1,ALDH1L1,RAB30,KDM2B,PLCD4,KAT7,ATOH8,BACH2,HNF4G,MSL1,RBPJ,KCNB1,LSAMP,MARK3,MAT2A,MEIS1,GIT1,MXI1,IGSF11,GPR137C,GNG2,ROBO2,HUNK,ATXN7,PRCD,FAM81A,FAM126B,IQSEC2,CLASP2,POGZ,LARP4,COBL,FBXW11,NSD1,NACC2,CBX5,OSBP2,LYPD6,GDPD5,GAN" MicroRNA hsa-miR-7110-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.58E-23 4.24E-19 1.87E-22 1.72E-21 59 349 "MTA3,SORCS2,SPOP,ARHGDIA,ATP1A3,PROM1,LDLRAD4,CABP7,CD86,RIMS4,CST3,PLXNA4,PITPNM3,GAPVD1,LONRF1,TMCC2,RCAN1,CELSR3,EMX2,SLC43A2,NRN1,GABRG2,PCDH17,GPT2,PARD3B,FRMD3,SHISA6,LSAMP,PALM,PDE3A,PLCL1,KANSL1,SNRK,PTPRN2,SH3TC2,RDX,SCN2B,GALNT10,ZFP30,CPEB3,ZFP1,LIMCH1,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,IQCE,BHLHB9,TNS1,SMUG1,TSC1,UBE2H,DPYSL5,CADM2,PRDM10,MPPE1,DPF3" MicroRNA hsa-miR-4301:mirSVR_highEffct hsa-miR-4301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.64E-23 4.28E-19 1.88E-22 1.73E-21 63 396 "AP2A2,ALDH7A1,DPY19L3,FUBP1,PRMT9,RUNX1T1,MAGI1,CFL2,SUMF2,ANKRD44,APPL1,GREB1,DDX46,RCAN1,DTNA,ZNF549,FER,POLR1B,FHL1,TPK1,ZNF605,GABRA3,CRCP,FERMT2,GRIA2,GRIN2C,AP4S1,HNMT,MSL1,C2orf72,SMAD1,MBNL1,MIA2,NDP,NFE2L2,PDE1C,XRN1,GPSM2,POLG,HYDIN,VPS13C,CNTLN,PTPRD,FIGN,ELP2,CCDC102B,NEK11,MEG3,CCDC88A,SLC9A5,MAPKBP1,USP33,ZNF302,NSFL1C,ZFP90,METTL3,AMACR,SGK3,UGT8,PLEKHH2,ZNF45,EML6,KCNAB1" MicroRNA "CTTGTAT,MIR-381:MSigDB" "CTTGTAT,MIR-381:MSigDB" MSigDB 7.89E-23 4.41E-19 1.94E-22 1.79E-21 44 192 "EIF4G3,CARMIL3,KALRN,QKI,OSBPL3,MBNL2,KCTD3,EIF4G2,PAN3,EIF1,EPB41,SRRM1,RRAGB,DLC1,FOXF2,SYNCRIP,NBEA,GAD1,C15orf41,GRM8,PSIP1,MAP4,MEIS2,MITF,KCTD15,PURG,PMP22,KANSL1,SNRK,ZNF532,SEMA6D,SATB1,SCAF8,SLC6A8,BTBD7,IQSEC2,ANKRD12,ZFPM2,R3HDM1,UBE3A,TBC1D15,VSNL1,NAV3,ST8SIA2" MicroRNA hsa-miR-4644:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-23 4.42E-19 1.94E-22 1.79E-21 50 251 "ADD2,CASKIN1,HACE1,TAOK1,PDZD4,SFMBT2,IGDCC4,BACH1,EPS15L1,ARHGEF6,ZNF385A,CSF1,CSNK1E,CNTNAP2,SLITRK5,TM9SF4,IP6K1,SPATA2,ZC3H11A,CHRDL1,ABCC5,E2F6,FGFR1,AMOTL2,AFF2,CELF1,SRCAP,TNRC6A,DCLK2,SLC6A17,ZFYVE27,ZC3H12B,GPR137C,PDE4A,PFKFB3,PKD1,PKM,PLCD1,PRRT2,MORC4,HSD11B1L,MRAS,BTBD3,PKNOX2,CCDC88A,IQSEC2,TMEM9,SLC38A1,SIGLEC10,ITM2C" MicroRNA hsa-miR-1915:mirSVR_highEffct hsa-miR-1915:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.90E-23 4.42E-19 1.94E-22 1.79E-21 67 445 "CLK4,PTCHD1,AP2A2,AMT,LGR5,CADPS,NCOA1,CFLAR,BTK,DDR1,VXN,SPAG9,CNTN1,MYRIP,GDA,CS,OSBPL3,TBC1D5,IP6K1,SPATA2,HEYL,FAM198B,HHIPL1,CRCP,COPS8,MSL3,GRM8,FAM19A2,IRAK3,VSIG4,ZNF678,MGAT3,MID1,DBNL,MYO7A,TBC1D25,PLCL1,TATDN3,TMEM260,ARMC5,YY1AP1,TRAPPC13,HKDC1,FHOD3,PREX2,SLC12A4,SMARCD3,KIF13A,NKAIN2,SYN1,DNMBP,WSCD1,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,KHDC1,PRRT1,PRDM8,URM1,CASC15,NHSL1" MicroRNA hsa-miR-4284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.07E-23 4.52E-19 1.98E-22 1.83E-21 82 642 "PLEKHH1,ESYT2,TBC1D14,TXNDC16,TAOK1,APAF1,CDC14B,BMP7,DIS3L,AKAP5,CRY2,HINFP,APPL1,GREB1,YTHDC1,GUCD1,KRBA2,HEYL,MRO,EIF5,TUBD1,EPB41,SLC43A2,IGSF6,SCML2,POLR1B,FGFR1,AMOTL2,PCYOX1,CINP,APOPT1,PDLIM5,MSANTD4,GABRB3,TRAF3IP2,CRCP,DBF4,RAB40B,BVES,IRAK3,DDX19B,NEGR1,IGF1,IL6R,KCNJ5,LIMS1,SAMD5,ZC3H12B,PDPK1,ZNF655,STRN3,EXOSC10,APTX,MTMR10,PEX2,NWD1,C12orf49,ELP2,SNX22,ZFP30,SH3BP2,R3HDM2,ZNF430,SEPHS1,ZKSCAN3,INAVA,UHRF1BP1L,ZNF621,POGZ,SS18,ZSCAN29,KLHL7,TPCN2,SLC19A3,PCDHA6,ZNF106,ARL10,ZNF708,ZNF17,FBXO36,ZDHHC20,NETO2" MicroRNA hsa-miR-564:mirSVR_lowEffct hsa-miR-564:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.60E-23 4.81E-19 2.11E-22 1.95E-21 72 509 "SYN3,XKR4,MTA3,AP2A2,ZNF578,LRFN1,PHYHD1,ARHGDIA,TMEM108,ATP1B3,RGS9,SYNJ2,BAIAP3,DCLK1,DLGAP1,LHX2,NRXN3,MAP4K4,CABP1,SMARCAL1,GREB1,BRINP1,DBI,TMCC2,HS3ST2,CDON,SRPK3,RABEPK,SLC43A2,EYA1,FLT1,FLYWCH1,FAM49B,BRSK1,PRUNE2,STON1,GRM2,BTN2A1,BLOC1S2,N6AMT1,PCDH8,PCDH9,FAM216A,SMOX,MAPKAP1,SDK2,MASP1,PTCH1,TUG1,SLC25A48,RASGRF2,KLHL11,ZFHX4,EXD2,SNX22,EPHA10,MAPK12,HSPA4L,DZIP1,LIMCH1,SP2,SSPO,KANK1,PCDHB6,NR2E1,WBP2,NUTM2A,RPRM,PLEKHH2,CLIP2,MEIS3,LAS1L" MicroRNA hsa-miR-6884-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.64E-23 4.83E-19 2.12E-22 1.95E-21 73 522 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,CEP126,LRFN1,AQP6,ARHGDIA,ZNF583,SYNJ2,CCNT1,SLC16A4,NRXN3,SUMF2,SLC35F1,CRY2,IPCEF1,RIMS4,UBXN2A,KIAA0408,MYADM,TMEM170A,ELMSAN1,DNAH9,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,ZNF589,ATP13A4,CRCP,GPR75,GLUL,ZNF638,GPT2,BVES,ATOH8,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,SLC11A2,PSD,APTX,MTMR10,TMEM145,QDPR,KLHDC8A,GSTCD,PTGR2,AMBRA1,SLC2A5,SEPHS1,CDK19,MCF2L2,DDN,LHPP,FAM208A,TPCN2,SLC19A3,PCDHA6,ARL10,SSBP2,EVI5,URM1,MPPE1" MicroRNA hsa-miR-614:mirSVR_lowEffct hsa-miR-614:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.72E-23 4.88E-19 2.14E-22 1.97E-21 64 409 "PTCHD1,BIN1,ARRB2,CASTOR3,LRRFIP1,SRSF11,HAPLN1,ANKRD44,SOCS5,CNTNAP2,MAML1,SCRN1,DMTF1,EDNRB,PHF20L1,IRAK4,C3orf18,FER,EFCAB2,CELF1,AP4B1,SDCBP2,ALDH1L1,GFER,ADGRA3,GRIA2,CLASRP,MAN1B1,METTL21A,KTN1,ZFYVE27,MEIS2,MITF,XRRA1,PRTG,PDPK1,GPSM2,FXYD1,PDZRN4,PMP22,CNNM2,MTMR10,RASGRF2,RIC8B,PNMA8A,PCMTD2,DZIP1,PEX26,BTBD3,ANKRD36,SNRPN,MYO16,FNBP1,SYN2,FAM208A,FBXW11,FAM189A1,OBSL1,DICER1-AS1,ZKSCAN5,ZBTB14,REEP1,ZFAND5,IFT88" MicroRNA hsa-miR-425-5p:TargetScan hsa-miR-425-5p TargetScan 8.92E-23 4.99E-19 2.19E-22 2.02E-21 45 202 "RNF150,AMPH,PHF12,ATP1B3,N4BP2L1,CALM1,RUNX1T1,DGKI,CFL2,HECTD1,RNF14,MATR3,MAML1,DGKG,PITPNC1,ELMSAN1,CDON,CPEB2,DPYSL2,DNAJB6,HIPK3,RGS17,DNAJC27,GABRB3,ARHGAP36,AGFG1,IGF1,ITPKB,MEF2C,MEIS1,GIT1,SDK2,PPP3CA,PTCH1,ANKHD1,PTPRN2,GTDC1,ALG9,EPN2,EPC1,KAT6B,RGMB,PRDM8,HNRNPA3,NETO1" MicroRNA hsa-miR-638:mirSVR_lowEffct hsa-miR-638:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-22 5.62E-19 2.47E-22 2.27E-21 63 398 "ADD1,ADORA2A,LGR5,RNF182,ADAM15,CFLAR,KCNAB3,NOG,UBE2L6,CPNE6,IGLON5,CNTFR,RBM39,ANKRD44,DCAF4,ARHGAP24,JAKMIP2,EXOG,SLC29A4,FARSB,FCF1,APH1A,EGR3,DCTN4,FGF11,CGREF1,TVP23A,CLASRP,AP4S1,MIER3,HLF,KIF5A,MEIS2,SRSF12,FXYD7,CNOT4,PCDH18,MAPKAP1,PRKAB2,USP47,PRRT2,ZFHX4,ATAT1,CCDC92,ZFP1,INTS9,RCOR3,KDM4C,CDK19,NFASC,SSPO,PJA1,CAMTA1,MLST8,HIF3A,RNF175,NUTM2A,CCDC136,LMF1,ZNF711,MICU3,INTS3,DNAH10" MicroRNA hsa-miR-892b:PITA hsa-miR-892b:PITA_TOP PITA 1.01E-22 5.64E-19 2.47E-22 2.28E-21 47 222 "USP31,SPOP,UNC79,DPP10,LDLRAD4,CAMK2G,FOXN3,SOCS6,CNN3,SEC24C,ERC2,LONRF1,KLHL3,RAB39B,DPYSL2,MAMLD1,APH1A,AFF2,CELF1,B4GALNT1,SRRM4,PCDH17,PPARGC1A,PCLO,PTPRT,MAP4K5,ZHX1,HMGCR,SMAP1,KIAA1755,GIT1,NNAT,SLC11A2,MAPK3,WBP1L,RAP1GDS1,ROBO1,TRA2B,CDK19,CLASP2,SS18,SYT1,NSD1,MICU3,CADM2,MSRB3,RNF146" MicroRNA hsa-miR-518a-3p:mirSVR_lowEffct hsa-miR-518a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-22 5.74E-19 2.51E-22 2.31E-21 76 563 "NDRG3,PSMG3-AS1,RNF150,OLMALINC,ASGR1,FUBP1,THSD7A,PRC1,CCPG1,SRSF11,SOCS6,QKI,SULT4A1,MAP4K4,ARHGEF6,MYRIP,ZNF521,ANKRD44,KCTD8,DAPK1,DGCR5,DMPK,SLC29A4,CDON,EDN1,SEMA3D,EIF1,MRPL37,IP6K2,NELFCD,SDCBP2,PCLO,AGBL5,MPP2,LYRM9,MYO6,RTL5,NME4,SLC11A2,NTRK2,OPA1,PFKFB2,MAPKAP1,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,GTDC1,SLC25A36,CCDC25,SCN2B,HSPA4L,CPEB4,IFT122,MAPKBP1,PDZRN3,KDM3A,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,RIMBP2,RGMB,TRIO,TSC1,UCHL1,CELF4,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-412:mirSVR_highEffct hsa-miR-412:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-22 7.45E-19 3.26E-22 3.00E-21 86 703 "NCKAP5,XKR4,ADD1,HECW2,KLHL13,PKP4,SPTBN4,PDE8B,NCOA1,DPY19L3,TTLL9,BACH1,CFLAR,SYNJ2,KALRN,SPAG9,RAB28,QKI,ARMC8,SUMF2,LETMD1,TRIM69,SNCAIP,PNPLA8,CTH,KATNAL2,ARHGAP24,DNM1L,MBNL2,MRNIP,STARD3NL,RABEPK,SRRM1,FDFT1,FER,SEMA4D,NOP56,ZNF638,CBX1,POLL,FAM19A2,RNF165,GUCY1B1,ZHX1,ZNF546,KPNA5,STXBP5,ZFYVE27,MAT2A,MEIS1,LYRM9,OGG1,TMEM38A,ING3,SEPT4,CEP41,HYDIN,PTN,CEP97,GTDC1,ROBO1,RORB,ELP2,LRRK2,NLGN1,SEPHS1,PDZRN3,RBM34,KDM4C,SSTR2,NKAIN2,SYNE2,KLHL4,ATMIN,TPCN2,USP32P1,TEK,DICER1-AS1,ITGB3BP,MTMR14,TST,UGT8,ZNF711,SIGLEC10,DNAH10,CASC15" MicroRNA hsa-miR-181a-5p:Functional MTI Functional MTI miRTarbase 1.47E-22 8.22E-19 3.60E-22 3.31E-21 75 553 "TMEM132B,MTUS1,HECW2,HFM1,MADD,ARRB2,PLA2G4C,MTMR3,AP1M1,ZNF445,ABCG2,MAP4K4,AKAP12,OSBPL3,SIPA1L1,PUM1,DCAF4,LONRF1,ELMSAN1,MTX3,E2F5,FSD1L,FAM13A,KCTD3,LRRC17,STX2,IQCG,SLC37A3,CHL1,PRRC2B,ZDHHC15,IPO5,NCOA7,BLOC1S2,PFKFB2,ZNF426,LRRN3,PPP2R5E,PPP3CA,C1orf109,ZNF844,PBRM1,MEG3,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,BTBD3,CPEB4,ZNF667,ZNF415,TMCC1,UNC5B,PRRC2C,MTCL1,TCF4,TRIM2,PCDHB6,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,TUBB2A,UCHL1,ZNF781,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-499-5p:PITA hsa-miR-499-5p:PITA_TOP PITA 1.51E-22 8.43E-19 3.69E-22 3.40E-21 47 224 "OSBPL1A,LRCH2,ZBTB10,PTBP2,CDO1,CFL2,MS4A7,NRXN3,QKI,HECTD1,SLC35F1,RNF14,FAM131B,MYEF2,USP3,DPP6,EPB41L2,SRRM1,CHL1,MAP4K5,RBPJ,MAP2,MEIS1,ZC3H12B,NOVA1,XRN1,MINDY2,PPP3CA,PTCH1,RET,PBRM1,FBXW7,NCBP3,CHD9,TRIM67,SLC12A2,SOX11,CDK19,SYT1,FLRT2,ZNF711,REEP1,MEIS3,SLC30A4,EVI5,WNK3,RNF146" MicroRNA hsa-miR-4300:mirSVR_highEffct hsa-miR-4300:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-22 9.20E-19 4.02E-22 3.70E-21 65 426 "CCDC85A,ADGRF5,LRFN1,PPFIA4,ARHGEF25,CBR1,CREM,NCOR1,SEC24C,RUBCN,CCDC144A,RHOBTB1,CHRDL1,C8orf37,SRRM1,NRN1,ZMYND15,FOLR2,HVCN1,DISC1,KIAA1841,SERP2,GUCY1B1,ZNF678,KCNK3,STXBP5,NCOA7,ASPRV1,CHIC1,CNOT4,NUCB2,PDE3A,PDE4D,ZNF655,MTRF1L,PPP2R2B,RNASEL,CARF,NEK11,PEAR1,COPZ1,BTBD3,TET1,GKAP1,NMNAT2,SPART,ATP10B,LARP4,ADHFE1,DMXL2,HIF3A,AP4E1,THRA,MTMR14,C9orf85,METTL3,GORASP1,CLDND1,SLC17A7,WNK3,EPM2A,DOCK8,KAT6A,IFT88,NETO2" MicroRNA hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA_TOP PITA 1.71E-22 9.57E-19 4.18E-22 3.85E-21 54 298 "KCNH8,PLEKHH1,INTS2,KCTD16,HACE1,TAOK1,ARHGAP20,ZBTB10,FUBP1,ARHGEF2,DCLK1,CFL2,QKI,KLHL3,ERBB4,MED12L,PSD2,HVCN1,FUT9,OGA,IQGAP2,LPAR4,GPR37,ZHX1,KTN1,MBNL1,MEIS2,NOVA1,PDE4B,PPP2R5E,ZSCAN32,RORB,ZC3H14,WDR47,CCDC88A,CPEB4,SMARCC2,KDM3A,STAU1,PLCB1,SYPL1,TACC1,FBXW11,ZEB1,RIMBP2,SGK3,VLDLR,CLDND1,SLC38A1,TMEM178A,NAV3,ADAMTSL3,FXR1,DPF3" MicroRNA hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA_TOP PITA 1.71E-22 9.57E-19 4.18E-22 3.85E-21 54 298 "KCNH8,PLEKHH1,INTS2,KCTD16,HACE1,TAOK1,ARHGAP20,ZBTB10,FUBP1,ARHGEF2,DCLK1,CFL2,QKI,KLHL3,ERBB4,MED12L,PSD2,HVCN1,FUT9,OGA,IQGAP2,LPAR4,GPR37,ZHX1,KTN1,MBNL1,MEIS2,NOVA1,PDE4B,PPP2R5E,ZSCAN32,RORB,ZC3H14,WDR47,CCDC88A,CPEB4,SMARCC2,KDM3A,STAU1,PLCB1,SYPL1,TACC1,FBXW11,ZEB1,RIMBP2,SGK3,VLDLR,CLDND1,SLC38A1,TMEM178A,NAV3,ADAMTSL3,FXR1,DPF3" MicroRNA hsa-miR-323-5p:mirSVR_highEffct hsa-miR-323-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-22 9.71E-19 4.24E-22 3.91E-21 62 390 "DGCR6,ABCF1,ADD2,PLEKHH1,CC2D2A,LTBP4,ATP1B3,ALDH7A1,TTLL9,BBS2,CBFA2T2,SEPT7,NRXN3,PPT2,IGLON5,CNR1,SLC4A8,SMARCAL1,KIF26A,PITPNC1,RHOBTB1,USP3,DPH1,WDPCP,PHC2,KMT5B,DCTN4,VPS13B,FOXF2,FYB1,CIT,MIER3,ELOVL5,MEIS1,MMP16,PDPK1,KANSL1,WBP1L,ENOX1,RBBP6,PNMA8A,ROBO1,ABCA11P,ATAT1,ZNF331,SGK1,FERMT1,NLGN1,FAM81A,SNRPN,CLASP2,ZSCAN29,RGL1,DMXL2,PCDHB4,THRA,MTMR14,TK2,PIK3R5,C9orf85,TRO,PRRT4" MicroRNA hsa-miR-331-5p:PITA hsa-miR-331-5p:PITA_TOP PITA 1.74E-22 9.76E-19 4.26E-22 3.92E-21 38 142 "ASIC1,SYNJ1,DLGAP2,IGDCC3,AKAP12,KIAA0408,DCAF8,DBT,JAKMIP2,RUSC2,RASGRP1,PAN3,FUT9,ARFIP1,HAS2,ELOVL5,DHX35,INSM1,GPR155,MBNL1,SHC3,MEF2C,MYCN,CNOT4,PCDH9,RANBP3L,RBBP8,RORB,SOX11,ELOVL4,RPGRIP1L,TCF12,SIRT1,KAT6B,LYPD6,CELF4,RNF103,RNF170" MicroRNA hsa-miR-1233:mirSVR_highEffct hsa-miR-1233:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.84E-22 1.03E-18 4.49E-22 4.13E-21 57 332 "FMNL2,ADD2,AXIN2,PLEKHH1,ADRB2,CC2D2A,NCOA1,SLC4A4,SYNJ2,SPAG9,LDB2,SPOCK2,MYEF2,DTNA,ECM2,E2F5,PHF20L1,LRRC17,PRMT5,FGF13,POLK,AKAP3,HRASLS5,PCLO,PRDM5,PSIP1,ZNF491,STXBP5,SYTL4,MYO9A,SFR1,NEK1,NTRK2,PCSK5,TMEM38A,GDPD2,RGS12,RNASE1,SUGCT,GSTCD,ROBO1,ATAT1,CNKSR2,SLC14A1,ELMO2,POGZ,VPS13A,COBL,MTCL1,KLHL4,MTMR14,SYNPO2,RPL7L1,LYPD6,MEIS3,HPS4,LAS1L" MicroRNA hsa-miR-127-3p:mirSVR_lowEffct hsa-miR-127-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-22 1.27E-18 5.53E-22 5.10E-21 61 380 "DGCR6,DPY19L2P4,AP2A2,RIPK1,SYNJ2,PTBP2,P2RX6,CDH2,L3MBTL4,MAGI1,DIS3L,ASIC3,DCAF4,BOC,DOCK4,GIT2,TIAM2,SGSM2,FCF1,TLR7,TBC1D16,KAT8,BAIAP2,TUBGCP4,COPS8,GPD2,GRIA2,SERP2,ARHGAP36,HMGCL,PTOV1,NF1,P2RX7,DPY19L2P2,MAPKAP1,SDK2,CEP41,PTPRD,TMEM145,CCDC40,FAM66C,RGS12,ZFHX4,SMPD3,ZNF667,CLASP2,TACC1,CAMTA1,NAT16,FAM189A1,AP4E1,TIAM1,TMPO,RASD2,OSBP2,NPDC1,GUSBP1,MICU3,ZBTB38,MEIS3,DNALI1" MicroRNA hsa-miR-1300:PITA hsa-miR-1300:PITA_TOP PITA 2.28E-22 1.28E-18 5.57E-22 5.13E-21 52 278 "TAOK1,PITPNM2,LCORL,PPFIA4,CADPS,ADGRB3,BCL7A,MAGI1,CACNA2D2,CLTC,HECTD1,HOMER3,SEC24C,ZFYVE16,ELMSAN1,DMD,DYNC1I1,EGR3,FGF13,UBE2E3,AFF2,FUT9,ARFIP1,GHR,TCERG1,BACH2,KIF5A,AQP11,MPP2,NBL1,CNOT4,GPR137C,PPP2R5E,RELN,PTCH1,FIGN,RGS4,ZFHX4,NCBP3,NLGN1,FAM81A,WDR47,KDM3A,PEG10,CAMTA1,TCF4,RPGRIP1L,TCF12,TCEAL7,REEP1,FZD3,HNRNPA3" MicroRNA hsa-miR-618:PITA hsa-miR-618:PITA_TOP PITA 3.06E-22 1.71E-18 7.46E-22 6.87E-21 51 269 "CDC42BPA,DPP10,ZBTB10,JAZF1,USP6,MAGI1,SRSF11,FOXN3,CNN3,RCHY1,NCOR1,CNTNAP2,HDAC4,SPOCK2,YTHDC1,MAMLD1,SEC24B,FGF13,FGFR3,LPAR4,GRB10,NEGR1,MARK1,MID1,NEXMIF,NFIX,NOVA1,GPR85,GNG2,LRP12,RAP1GDS1,FIGN,ZC3H14,MCMBP,SALL1,CPEB3,FHOD3,PPP4R3A,TET1,FNBP1,SOX11,SP4,KDM4C,ZNF423,SYT1,DMXL2,WIPF1,ZNF711,CELF4,RNF146,SOCS4" MicroRNA hsa-miR-520h:Functional MTI Functional MTI miRTarbase 3.37E-22 1.89E-18 8.22E-22 7.57E-21 63 407 "XKR4,PLEKHH1,ZNF578,SMIM17,ATP1B3,LDHD,ZBED1,DIS3L,CFL2,ABCG2,ZNF385A,ENTPD4,DCAF8,DNAL1,RAB39B,DMD,SLC12A6,DNAJB6,HIPK3,CELSR3,IRAK4,PLEKHA1,RGS17,COQ7,TLR7,SCML2,GTF2IRD2,SEMA4D,MSANTD4,TRAF3IP2,SYT17,KIAA1841,SRCAP,TNRC6A,PRUNE2,FICD,HAS2,NKD1,METTL21A,GPR155,MAPT,P2RX7,PIK3C2A,ZNF426,PPP2R5E,PEX2,KLHL11,C12orf49,HSPA4L,ATF7IP,SP2,CEP68,STAC2,SATB2,GPRIN3,ZMAT3,CBX5,TMPO,PARD3,VLDLR,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-6758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.39E-22 1.90E-18 8.27E-22 7.61E-21 50 259 "ADD2,CASKIN1,HACE1,SORCS2,TAOK1,TRMT9B,CDC42BPA,SFMBT2,IGDCC4,BACH1,BCL7A,ARHGEF6,PDE4DIP,SEC14L5,TM9SF4,IP6K1,DNAL1,CHRDL1,MAMLD1,E2F6,APH1A,PCYOX1,AFF2,HHIPL1,SRCAP,TNRC6A,RABL2A,SHISAL1,SLC6A17,HS6ST3,ZC3H12B,NFIX,KSR2,ZNF827,PDE4A,PFKFB3,PKM,PTPRB,NKAIN1,FIGN,PTGR2,STX1B,NCBP3,AMBRA1,SEPHS1,SEPT8,NSD1,TUBB2A,ZNF70,SIGLEC10" MicroRNA hsa-miR-3613-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-22 1.92E-18 8.37E-22 7.70E-21 71 508 "PTCHD1,SLC24A4,EIF4G3,ZNF582,CD38,CFL2,HECTD1,TBPL1,HINFP,PHF14,USP6NL,RASSF2,TMEM170A,ELMSAN1,HEPH,GUCD1,SGSM2,MTX3,HIPK3,FCF1,TMTC1,CERCAM,C8orf37,ZNF549,FGF12,SPECC1,CELF1,MALT1,FUT10,GRB10,BVES,FRMD3,ZNF678,KCNB1,KCNN3,DBNL,NFYA,CNOT4,IGSF11,PDE3A,GPR85,PDZRN4,GDPD1,KLHL11,KLHDC8A,GSTCD,ZNF568,NCBP3,TRA2B,SH3BP2,PPP4R3A,BTBD3,SLC14A1,KIF13A,FAM126B,FNBP1,UHRF1BP1L,POGZ,MPRIP,ADAMTS17,CLASP1,DICER1,ZMAT3,TUBB2A,UBE3A,ZNF28,NDRG4,ADAMTS9,KCNAB1,WNK3,DPF3" MicroRNA hsa-miR-4510:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.85E-22 2.15E-18 9.37E-22 8.63E-21 54 303 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,SETD5,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA hsa-miR-490-5p:PITA hsa-miR-490-5p:PITA_TOP PITA 3.93E-22 2.20E-18 9.57E-22 8.81E-21 38 145 "TAOK1,MARCH4,FAM135A,USP37,SYNJ1,CDH2,CNOT8,PLCXD3,DPP6,EGR3,PRKAG2,AFF2,MSTN,TOX3,FERMT2,GRIA2,MIER3,ZIC5,KIAA1755,MAT2A,CHIC1,NTRK2,CCSER2,WBP1L,TMEM260,PTPRD,ROBO1,LRFN5,FAM102A,FNDC3A,BTBD3,CCDC88A,ZNF423,ARHGAP26,SZT2,TRPS1,ZIC1,FRMD6" MicroRNA hsa-miR-383:PITA hsa-miR-383:PITA_TOP PITA 4.39E-22 2.46E-18 1.07E-21 9.83E-21 37 137 "GALNT13,MTUS1,OGT,ZBTB10,CACNB4,DCLK1,FOXN3,PLCXD3,SACS,SV2B,EDN1,ELN,PAN3,TAOK3,CSPG5,GABRB3,PCDH17,MEF2C,ZC3H12B,NNAT,CNOT4,PIK3R1,RETREG1,MAPKAP1,STRN3,TMEM260,PTPRE,UBR7,SHMT2,AMBRA1,FAM126B,CDK19,RBM26,TCF4,FRYL,DICER1,TRPS1" MicroRNA hsa-miR-6833-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.54E-22 2.54E-18 1.10E-21 1.02E-20 57 338 "RNF157,SPOP,MARCH4,USP37,PTCH2,ATP1A3,CABP7,CD86,CST3,PITPNM3,ZSCAN23,MAML1,C2CD2L,EDN3,EMX2,CELF1,GALC,GATM,SULT1C4,PCDH17,FRMD3,NEGR1,IL6R,LSAMP,GPR155,NFIX,NPTX1,P2RX7,PLCL1,PKIA,SNRK,PTPRN2,ZSCAN2,RDX,FIGN,ATXN7,CPEB3,CHD9,SLC6A8,ZNF667,ZNF415,RBM26,TROVE2,DIP2A,ANKRD28,EXOC7,MGRN1,TNS1,TSC1,SGK3,ZNF23,DHX33,CADM2,PRDM10,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-891a:mirSVR_lowEffct hsa-miR-891a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.54E-22 2.54E-18 1.10E-21 1.02E-20 57 338 "ADCY6,PWWP2A,KIAA1324,SEMA6A,GPRASP2,RGS20,SYNJ1,CACNB4,LOC730101,CCPG1,RAB28,PPT2,CNR1,LETMD1,NCOR2,TRIM69,PDE4DIP,ARMCX4,DUSP9,TSPAN5,PHF20L1,SUGP2,EIF4G2,EIF5,F5,RACK1,CHST15,FGF1,FOXF2,C2orf88,EFCAB2,PDLIM5,IP6K3,TCERG1,TOX3,ZNF638,LNX1,RNF165,HAS2,HMGCL,KCND2,A1BG-AS1,TM6SF1,PPARA,PPP3CA,RANBP3L,CYBC1,RGS4,EPHA10,MCMBP,COPZ1,WDR47,SEPT8,CEP68,ARHGEF9,CSMD1,LGI4" MicroRNA hsa-miR-4768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.54E-22 2.54E-18 1.10E-21 1.02E-20 57 338 "RNF157,SPOP,MARCH4,USP37,PTCH2,ATP1A3,CABP7,CD86,CST3,PITPNM3,ZSCAN23,MAML1,C2CD2L,EDN3,EMX2,CELF1,GALC,GATM,SULT1C4,PCDH17,FRMD3,NEGR1,IL6R,LSAMP,GPR155,NFIX,NPTX1,P2RX7,PLCL1,PKIA,SNRK,PTPRN2,ZSCAN2,RDX,FIGN,ATXN7,CPEB3,CHD9,SLC6A8,ZNF667,ZNF415,RBM26,TROVE2,DIP2A,ANKRD28,EXOC7,MGRN1,TNS1,TSC1,SGK3,ZNF23,DHX33,CADM2,PRDM10,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-563:mirSVR_highEffct hsa-miR-563:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.83E-22 2.70E-18 1.17E-21 1.08E-20 58 350 "ACHE,KIAA1211,PTCHD1,KLHL13,KCTD16,C1QTNF3,PHF12,BACH1,ISPD,ABCG2,GDA,CSNK1G3,SOCS5,PNPLA8,ARHGAP32,LONRF1,ZC3H11A,ECM2,CLVS1,KAT8,FGF13,POLK,IGSF5,TCERG1,RAB30,ZNF782,SERP2,RNFT2,ARHGAP36,TCEAL6,SMAP1,GAREM2,CREG2,SYTL4,NRBP2,SLC11A2,NUCB2,PPM1B,PRKACB,CNTLN,RGS4,PBRM1,PNMA8A,ATP8B4,RTN1,SCN8A,DZIP1,ZNF334,ANKRD36,SNRPN,TRIO,UBE3A,CLDND1,GUSBP1,MFF,KCNAB1,FIP1L1,WNK3" MicroRNA hsa-miR-548b-3p:PITA hsa-miR-548b-3p:PITA_TOP PITA 4.88E-22 2.73E-18 1.19E-21 1.09E-20 47 230 "PCDH19,OSBPL8,SEMA6A,CPNE5,BCL7A,JAZF1,LDB2,CERS5,DLGAP2,SOCS6,RIMS4,MATR3,CPEB2,GOLT1B,CNNM1,KMT5B,PAN3,STX2,DLC1,FGF13,DCTN2,NBEA,STAU2,PPARGC1A,RNF165,ADAMTS6,ZIC5,GPR155,LRP1B,IGSF11,POLG,TMEM255A,NUDT11,SALL1,SMPD3,EPN2,RCOR3,RBM26,LARP4,NSFL1C,PLCB1,PUM2,DICER1,NR2E1,USP1,TOM1L2,SMARCAD1" MicroRNA hsa-miR-4281:mirSVR_lowEffct hsa-miR-4281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.01E-22 2.80E-18 1.21E-21 1.12E-20 63 410 "GALNT16,SLC24A4,LRFN1,SEC11C,RGS9,MIR9-3HG,PTBP2,RHBDL1,CBR1,P2RX6,EPS15L1,SOCS5,IST1,SGSM2,DNM1,TOM1,DNAJB6,SEZ6L2,TSPAN5,APH1A,ERBB2,SPEG,DNAJC27,FER,ATP13A4,ZNF276,STARD3,AGBL5,MAN2A2,MARK1,MAT2A,MBD1,MBNL1,TM6SF1,MEIS1,SMIM11A,SETD4,TMIE,MAPK3,MAPK4,MAPK9,NCBP3,SMPD3,PPP4R3A,SLC11A1,CPEB4,ZNF667,SNCA,CMTR2,MYO16,SPTB,TSPYL2,SSTR1,TRIM2,TNS2,KHDC1,TK2,CDK20,PPIL6,PLPPR2,CELF4,MEIS3,SLC30A3" MicroRNA hsa-miR-6133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-22 2.96E-18 1.28E-21 1.18E-20 54 305 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF17,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA hsa-miR-6127:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-22 2.96E-18 1.28E-21 1.18E-20 54 305 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPCN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA hsa-miR-3924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.67E-22 3.17E-18 1.37E-21 1.27E-20 48 241 "TMEM132B,ZNF608,HACE1,PCDH10,CCDC74A,BACH1,CA12,KIAA0408,DOCK4,MYADM,DCAF8,SV2B,YAF2,MBNL2,CERCAM,SCML2,ZBED3,FYN,GABRG1,GCK,SESN1,BVES,ZIC5,IL6ST,KLHL23,L1CAM,MKLN1,MMP16,NCAM2,NELL2,PIK3R1,PPP1R1A,CNNM2,PTPRD,RIC8B,PGBD4,CSRNP3,BTBD3,SEPHS1,SLC8A1,PRRC2C,SYPL1,TBCEL,BEX4,CSMD1,MAP3K12,ADAMTS9,NETO2" MicroRNA hsa-miR-1286:mirSVR_highEffct hsa-miR-1286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.99E-22 3.35E-18 1.45E-21 1.33E-20 72 526 "FAHD2CP,KIAA1324,EPB41L5,BCAS1,TNRC6C,PLA2G4C,CHRD,SLC2A11,CACNA1A,CALB2,KALRN,DGKI,DLGAP1,TIGD7,CFL2,DGCR9,CNR1,LETMD1,SEC24C,PDE4DIP,DOCK4,GAPVD1,DNM1,USP3,DNAJB6,DNM1L,YAF2,KMT5B,TMEM132E,LRRC17,F8,FGF14,SYNCRIP,IQCG,TMEM107,PCDH17,TDRKH,IRAK3,GATD1,PIK3AP1,MBD1,MYO9A,TCEAL5,PCSK5,PIK3C2A,SMOX,HYDIN,ZDHHC14,TRIM68,PRRT2,DCUN1D2,ARMC5,RORB,CASC3,SH3GL3,FBXO11,DHX30,CPEB4,CDK5RAP2,SMARCD3,MYCBP2,ZNF423,PRRC2C,SLC37A2,TAL1,PCDHB7,FAM200B,ARL10,CHST5,SLC35A4,WNK3,DNAH10" MicroRNA "TCTCTCC,MIR-185:MSigDB" "TCTCTCC,MIR-185:MSigDB" MSigDB 6.02E-22 3.37E-18 1.46E-21 1.34E-20 34 114 "PCDH10,PRX,ATP1A3,CARMIL3,ADGRB1,MAGI1,FOXN3,CPNE6,ZNF385A,PITPNC1,C2CD2L,CORO2B,KCNN3,MAT2A,NTRK3,PTPRE,RIC8B,ATAT1,LRFN5,NFASC,PHLDB1,SLC37A2,ASTN2,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,SSBP2,SLC30A3" MicroRNA hsa-miR-4459:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.25E-22 3.50E-18 1.51E-21 1.39E-20 84 691 "ABCF1,ADD2,SLC24A4,CASKIN1,HACE1,TXNDC16,SMIM17,PHF12,APAF1,ZNF583,DDR1,ISPD,CBS,EVI5L,CDR1,CACNA2D2,NDST3,NRXN3,NCOR2,SUSD5,CTH,USP6NL,MYADM,GAPVD1,RASSF2,LONRF1,TMEM170A,ELMSAN1,MTX3,DNAH9,MRO,ZNF549,ANKMY1,ZNF585B,MTHFD2,SESN1,GPR75,GLUL,LUZP2,GNG4,LILRA2,ZBTB49,RABL2A,ATOH8,AGBL5,SHISA6,IGF1,KCNJ5,KIF5A,STMN1,CHST6,PPM1L,MMP17,MPP2,SFR1,NFIX,ZNF713,CCSER2,PLEC,PPARA,PPP2R2B,NCR3LG1,MTMR10,ZNF844,CEP97,RBBP8,MSANTD2,RGS12,PTGR2,FNIP1,STUM,PREX2,SLC2A5,ATF7IP,FNBP1,MCF2L2,NEK4,HIF3A,SSBP2,ZNF610,LAT2,ZNF17,ZFAND5,INTS3" MicroRNA hsa-miR-122-5p:Functional MTI Functional MTI miRTarbase 7.53E-22 4.22E-18 1.82E-21 1.68E-20 78 609 "ABCF1,CLK4,XKR4,RNF157,ESYT2,HECW2,ANK2,EP400,CPNE5,DOCK11,WASF1,ISPD,SPAG9,NUMBL,FBXO7,CNN3,AKAP5,ENTPD4,CS,PHF14,PYGO1,IST1,DBT,KRBA2,OPTN,EGFR,TUBD1,KATNAL1,SEC23B,CINP,SPECC1,STAU2,GPR75,TNRC6A,GLUL,LILRA2,KAT7,IBA57,LIMS1,GPR155,MKLN1,SLC11A2,PFKFB2,OLA1,NLGN3,NALCN,ZNF655,PKM,GPSM2,PMP22,PIGG,PGBD4,SNX22,PTGR2,NCBP3,GALNT10,HSPA4L,FAM102A,ANKRD36,NMNAT2,ERC1,PEG10,CDK19,SSTR2,MPRIP,KLHL7,ALG1,GPR161,ZNF106,SLC44A1,UBTF,OSBP2,ZNF74,ZNF154,PARP11,TIGD6,RNF170,CPNE4" MicroRNA hsa-miR-6856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.60E-22 4.25E-18 1.84E-21 1.69E-20 49 253 "ADD2,CASKIN1,HACE1,SORCS2,TAOK1,TRMT9B,CDC42BPA,SFMBT2,IGDCC4,BACH1,BCL7A,ARHGEF6,PDE4DIP,SEC14L5,TM9SF4,IP6K1,DNAL1,CHRDL1,MAMLD1,E2F6,PCYOX1,AFF2,HHIPL1,SRCAP,TNRC6A,RABL2A,SHISAL1,SLC6A17,HS6ST3,ZC3H12B,NFIX,KSR2,ZNF827,PDE4A,PFKFB3,PKM,PTPRB,NKAIN1,FIGN,PTGR2,STX1B,NCBP3,AMBRA1,SEPHS1,SEPT8,NSD1,TUBB2A,ZNF70,SIGLEC10" MicroRNA hsa-miR-626:PITA hsa-miR-626:PITA_TOP PITA 7.61E-22 4.26E-18 1.84E-21 1.69E-20 37 139 "SEMA6A,SPOP,STK33,HAP1,MAGI1,TPP1,CNR1,COL4A5,RBM39,OSBPL3,ZC3H11A,PAN3,GPHN,CAMKK2,ARFIP1,ZHX1,BACH2,KIF2A,MBNL1,MEIS2,MITF,GNG2,MAPK3,NUDT11,ZC3H14,PPM1E,SEPHS1,TMCC1,SOX11,ZSWIM8,HECW1,PLCB1,SYT1,OSBP2,ZBTB14,ZBTB38,PDSS2" MicroRNA hsa-miR-3163:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.20E-22 4.59E-18 1.98E-21 1.82E-20 57 342 "XKR4,ADD2,ZNF608,WDR35,TXNDC16,SPOP,NUMB,ZNF582,NRP2,CALM1,RUNX1T1,NECTIN3,OSBPL3,USP6NL,CENPL,MTX3,CDON,CPEB2,MRVI1,ACSL4,SCML2,DLC1,MSANTD4,GABRB3,GCK,TCERG1,COPS8,RNPS1,TNRC6A,PRRC2B,USP51,ZIC5,SCIN,STMN1,CHIC1,ZNF680,IGSF11,PPP2R5E,PTPRD,REV3L,GTDC1,KLHL11,TMLHE,CLIP1,CHD9,BTBD3,SLC6A8,TROVE2,ZC3H4,PRRC2C,ARC,TBCEL,TBL1X,TPCN2,RGMB,TUBB2A,GAN" MicroRNA hsa-miR-2861:mirSVR_highEffct hsa-miR-2861:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.72E-22 4.88E-18 2.11E-21 1.94E-20 62 402 "SYS1,CC2D2A,PCDHGB4,NUMB,SRSF11,STOML1,DDX46,DPP6,EDNRA,SUGP2,COQ7,RASGRP2,RACK1,FCGRT,PSD2,ALDH1L1,USP19,PPARGC1A,ATE1,COQ10A,TCEAL6,KIAA1755,MBNL1,MYO7A,NCF2,NME4,NOVA1,DNHD1,TBC1D25,PCDHGC3,ANKRD16,EXOSC10,EPDR1,GRAMD1C,WBP1L,PTPRD,RASGRF2,PBRM1,ATAT1,SEC14L1,SMARCD3,MYH15,KDM4C,DBNDD2,ADHFE1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,TNS2,SIRT1,CDK20,AMACR,REEP1,CASC15" MicroRNA hsa-miR-379:mirSVR_highEffct hsa-miR-379:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.90E-22 4.98E-18 2.15E-21 1.98E-20 61 390 "HECW2,OSBPL6,CC2D2A,OGT,PKP4,TMEM108,ZNF582,MTMR2,MAGI1,CNOT8,FAM149A,IGDCC3,DOCK4,DPP6,E2F6,EDN1,FRY,EIF4G2,ETV1,PIPOX,UBE2E3,SLC37A3,GALNT15,PCDH17,RAB30,STARD3,FUT10,GRM8,MAP4K5,SMAP1,IDH3A,GAREM2,IL6ST,NME9,KIF5A,KCTD6,MSR1,DNHD1,SMIM11A,OXTR,MTRF1L,MINDY2,PTK2,NUDT11,RNASEL,MRAP2,LRRK2,HSPA4L,FNDC3A,CCDC88A,TEX2,CDK19,TTBK2,SYPL1,MMS19,ADGRL3,BEX4,MTCH1,EMSY,ADAMTS9,TRAM2-AS1" MicroRNA hsa-miR-328:mirSVR_highEffct hsa-miR-328:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.95E-22 5.57E-18 2.40E-21 2.21E-20 62 403 "NDRG3,PTCHD1,CC2D2A,ZNF578,ADGRF5,OGT,APOC2,PLA2G4C,CHRD,TTLL9,RUNX1T1,RAB28,NRXN3,SLC4A8,HAPLN1,TIAM2,DYNC1I1,FAM78B,FRY,PHF20L1,PLEKHA1,MRPL10,PRKAG2,WDR83,LRRC37A6P,ADAM28,LYVE1,FERMT2,ATOH8,PADI2,VSIG4,AGBL5,IL6ST,KCNH2,KIF2A,LMO2,CLEC18A,DNHD1,NUCB2,P2RX7,PCSK5,DUSP26,PRPSAP2,SNRK,RBBP6,ERI2,MORC4,RGS4,LRRK2,SOX11,ZNF423,NECAB1,PLCB1,SYT1,COBL,MTCL1,SYNE1,KAT6B,SMUG1,PLPPR2,ATP6V0E2,FRMD6" MicroRNA hsa-miR-380*:mirSVR_highEffct hsa-miR-380*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-21 5.70E-18 2.45E-21 2.26E-20 59 367 "ACHE,KIAA1211,PTCHD1,KLHL13,KCTD16,C1QTNF3,PHF12,EIF4G3,BACH1,NRP2,ISPD,GDA,OSBPL3,CSNK1G3,PNPLA8,GRIN3A,ECM2,CLVS1,FGF13,POLK,FAM49B,IGSF5,TCERG1,RAB30,ZNF782,PLCD4,SERP2,TCEAL6,SMAP1,GAREM2,CREG2,SYTL4,NRBP2,NCF2,SLC11A2,NUCB2,ZNF713,PPM1B,PRKACB,CNTLN,FIGN,NUDT11,PBRM1,PNMA8A,ATP8B4,RTN1,SCN8A,ZNF334,ANKRD36,SNRPN,CEP68,SYPL1,UBE3A,CLDND1,GUSBP1,MFF,KCNAB1,FIP1L1,WNK3" MicroRNA hsa-miR-10a*:mirSVR_highEffct hsa-miR-10a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-21 5.78E-18 2.49E-21 2.29E-20 56 332 "CLK4,FMNL2,KIAA1324,LCORL,FAM131A,SGCE,CALB1,CAMK2G,KRIT1,CD38,ZMYM4,ABI3BP,ABCG1,OSBPL3,CTH,DBN1,ARMCX4,DMD,E2F6,EBF1,EDNRA,YAF2,EPB41L2,GPHN,VPS26C,EYA1,ERGIC3,MEGF10,RAPGEF6,LPAR4,GRIA2,KIFC3,HECTD2,MARK1,NTRK2,ING3,HYDIN,ZNF615,RADX,SETD5,EXD2,ELP2,CLIP1,ATXN2,SEC31A,PPP4R3A,SLC14A1,MBD5,KDM4C,MTCL1,CLASP1,NR2E1,TSN,PLEKHH2,RICTOR,NETO1" MicroRNA hsa-miR-767-3p:PITA hsa-miR-767-3p:PITA_TOP PITA 1.08E-21 6.04E-18 2.60E-21 2.39E-20 45 214 "KCNH8,USP31,RTL9,SPOP,ALCAM,CHRD,THSD7A,DLGAP2,CNR1,DOCK4,TIAM2,FBXL5,C2CD2L,GRIN3A,NR1D2,EIF5,TMEM35A,CLVS1,PCYOX1,STAU2,PCLO,FAM19A2,MIER3,KIF2A,MAP2,AFF1,MN1,PTOV1,NEFH,GPR85,MAPK9,SNRK,PTCH1,TMEM255A,SCN8A,CPEB4,FAIM2,HECW1,LARP4,PRRC2C,SYT1,ANKRD28,CAMTA1,TNS2,POLR3H" MicroRNA hsa-miR-576-3p:PITA hsa-miR-576-3p:PITA_TOP PITA 1.08E-21 6.04E-18 2.60E-21 2.39E-20 45 214 "INTS2,APBB2,ATP2A2,ADGRB3,BCHE,LRBA,CCPG1,QKI,SLC35F1,ERC2,RIMS2,LONRF1,MFAP3L,SLC12A6,PLEKHA1,TMEM35A,STX2,PRKAG2,EFCAB2,PPARGC1A,TOX3,KDM2B,STON1,GRIA2,ZIC5,LSS,CHIC1,KITLG,MSI1,P2RY1,ANKRD16,STRN3,LRP12,PPP2R5E,MSANTD2,SGK1,FNDC3A,SLC8A1,PDZD2,SYN1,SYPL1,DOCK9,CSMD1,REEP1,ADAMTSL3" MicroRNA hsa-miR-520g-3p:Functional MTI Functional MTI miRTarbase 1.13E-21 6.35E-18 2.73E-21 2.51E-20 62 404 "XKR4,PLEKHH1,ZNF578,SMIM17,ATP1B3,LDHD,ZBED1,DIS3L,CFL2,ZNF385A,ENTPD4,DCAF8,DNAL1,RAB39B,DMD,SLC12A6,DNAJB6,HIPK3,CELSR3,IRAK4,PLEKHA1,RGS17,COQ7,TLR7,SCML2,GTF2IRD2,SEMA4D,MSANTD4,TRAF3IP2,SYT17,KIAA1841,SRCAP,TNRC6A,PRUNE2,FICD,HAS2,NKD1,METTL21A,GPR155,MAPT,P2RX7,PIK3C2A,ZNF426,PPP2R5E,PEX2,KLHL11,C12orf49,HSPA4L,ATF7IP,SP2,CEP68,STAC2,SATB2,GPRIN3,ZMAT3,CBX5,TMPO,PARD3,VLDLR,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-378b:mirSVR_highEffct hsa-miR-378b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-21 6.38E-18 2.74E-21 2.52E-20 82 669 "ARHGAP20,FAM135A,FGD2,DDO,TNRC6C,PLA2G4C,EIF4G3,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,TIGD7,C4orf33,AHCTF1,ZFP28,CREM,ARHGEF10,USP6NL,GRIN3A,GOLT1B,HIPK3,CELSR3,KMT5B,SPEG,FCGR1A,FCGR3A,FGF12,ATP5PD,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRG2,ERAP1,GPT2,TDRKH,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,SMAP1,MYLK2,IL6ST,KIF2A,MAP6,MARK1,LYRM9,NDP,NEK1,NF1,NFE2L2,CHAMP1,LOC100128398,TRHDE,PRPSAP2,PTPRD,USP47,BAALC,KCNIP1,MBD5,IQSEC2,NEK4,SEPT8,PLCB1,CAMTA1,AGTPBP1,DMXL2,FRYL,ZFPM2,AP4E1,PPIL6,GUSBP1,EML6,ZNF189,EPM2A" MicroRNA hsa-miR-6731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-21 6.40E-18 2.75E-21 2.53E-20 58 356 "ELFN2,HACE1,TAOK1,PDZD4,PPFIA4,PPFIA3,CDC14B,SFMBT2,SEMA4G,ADGRB2,HAP1,ARHGEF2,EPS15L1,ARHGEF6,SUMF2,RGS6,TM9SF4,SGSM2,CHRDL1,ABCC5,MRO,ING4,MTSS1L,FGFR1,AMOTL2,AFF2,GLYR1,GLUL,MIER3,SHISA6,IDH3A,SLC6A17,KCNK3,PPM1L,SAMD14,ZC3H12B,GPR137C,PDE4A,KCTD15,SDK2,PPARA,PTPRE,NKAIN1,MORC4,RNH1,SETD5,CCDC88A,ATF7IP,SP2,ERC1,IQSEC2,ZSCAN29,ARC,ASTN2,TUBB2A,ZNF70,SIGLEC10,ACTR3B" MicroRNA hsa-miR-8085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-21 6.40E-18 2.75E-21 2.53E-20 58 356 "ELFN2,HACE1,TAOK1,PDZD4,PPFIA4,PPFIA3,CDC14B,SFMBT2,SEMA4G,ADGRB2,HAP1,ARHGEF2,EPS15L1,ARHGEF6,SUMF2,RGS6,TM9SF4,SGSM2,CHRDL1,ABCC5,MRO,ING4,MTSS1L,FGFR1,AMOTL2,AFF2,GLYR1,GLUL,MIER3,SHISA6,IDH3A,SLC6A17,KCNK3,PPM1L,SAMD14,ZC3H12B,GPR137C,PDE4A,KCTD15,SDK2,PPARA,PTPRE,NKAIN1,MORC4,RNH1,SETD5,CCDC88A,ATF7IP,SP2,ERC1,IQSEC2,ZSCAN29,ARC,ASTN2,TUBB2A,ZNF70,SIGLEC10,ACTR3B" MicroRNA hsa-miR-4286:mirSVR_highEffct hsa-miR-4286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-21 6.51E-18 2.80E-21 2.57E-20 61 392 "RALGAPA1,XKR4,ADCY6,ADD1,PWWP2A,SPTBN4,ATP1A3,SLC4A4,PRMT9,GPC2,CALB2,PTBP2,MTMR7,LRBA,ENTPD4,SEC24C,PDCD6IP,DTNA,DENND4A,ABCA8,FAM198B,GABBR1,GABRA3,TRAF3IP2,TMEM8B,TNRC6A,CBX1,MSL1,DISP2,KCND1,MAN2A2,MBNL1,NFE2L2,NPTX2,PDE4A,STRN3,TMEM104,WDR25,BDNF-AS,RGS3,ROBO1,RORB,PCMTD2,ADAL,HKDC1,PPP4R3A,DMRTC1,SNCA,SOX3,TACR1,MCF2L,ADGRL3,KHDC1,TTTY15,SLC35A4,LGI4,FSTL5,SH3GLB2,SMIM8,CASC15,MSRB3" MicroRNA hsa-let-7d*:mirSVR_highEffct hsa-let-7d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-21 6.73E-18 2.89E-21 2.66E-20 43 195 "CLK4,BEND6,DGKI,AKAP6,ARHGEF10,ERC2,TBC1D5,KIAA0753,RCAN1,MBNL2,ABCA8,ANKFY1,UFM1,CAMKK2,C15orf41,GNAO1,ZNF782,GUCY1B1,RASSF8,MIER3,HMGCR,LRRCC1,MAP4,MYCN,PRTG,EPB41L4B,TATDN3,KANSL1,PRKACB,PTPRD,FAM184A,RASGRF1,MRAP2,ZNF331,RADIL,NKAIN2,NXT2,SYN2,TMPO,GUSBP1,KCNT2,PARP11,RGS7BP" MicroRNA hsa-miR-224-5p:TargetScan hsa-miR-224-5p TargetScan 1.29E-21 7.20E-18 3.09E-21 2.84E-20 55 322 "ADCY6,ADD2,ADRA1B,HECW2,PPFIA4,PHF12,APBA2,ATP1B3,NRP2,CAST,C1orf52,CACNA2D2,QKI,PCYT1B,SEC14L5,PYGO1,ARMCX2,FBXL5,DNM1,DPYSL2,HIPK3,MBNL2,EIF5,CEP85L,PSD2,FAM49B,FUT9,DOT1L,HMGCR,IGFBPL1,IL6ST,KLHL23,L1CAM,MYO5A,NOVA2,PDE1C,GPR173,PIK3C2A,GDPD1,RELN,PTX3,RASGRF2,ERI2,C12orf49,PCMTD2,CASC3,KDM3A,POGZ,ANKRD12,CYB561A3,CBX5,C9orf85,DPYSL5,DHX33,KAT6A" MicroRNA hsa-miR-1975:mirSVR_highEffct hsa-miR-1975:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-21 7.44E-18 3.19E-21 2.94E-20 74 560 "NDRG2,FMNL2,AK2,SPOP,UPRT,BCAS1,NUMB,ATP1A1,FUBP1,C5,ZNF501,CNTN1,TRIM69,PNPLA8,HDAC4,SNAP91,WDR20,NR1D2,ANKRD46,FRY,PHF20L1,RACK1,ATP13A4,DCTN2,JKAMP,WASHC2A,TXNL4A,GNAO1,TOX2,NKD1,GAREM2,INSM1,CREG2,STXBP5,MAT2A,PRTG,GPR173,GNG2,PLIN1,EPDR1,WBP1L,TMEM260,STRC,ZNF793,DPF2,RNASEL,RPE,SPIN3,FBXO11,NLGN1,SLC8A1,CCDC88A,SLC14A1,IFT122,HECW1,KDM4C,TEX2,SSTR2,ELOVL4,VPS13A,PLCB1,SYN2,ZEB1,SIRT1,TMPO,RIMBP2,STXBP4,PRR18,CCDC136,LAT2,CFAP298,ZIC2,UBE3B,CASC15" MicroRNA hsa-miR-6868-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-21 7.53E-18 3.23E-21 2.97E-20 42 186 "RALGAPA1,XKR4,FMNL2,GALNT13,RNF157,ADD1,SPOP,CDC42BPA,SFMBT2,DDR1,LURAP1,LRRFIP1,B4GALT6,PLCXD3,TM9SF4,CPEB2,OPTN,RGS17,EMX2,EPHB1,ERBB2,ST3GAL6,ZMAT1,LYVE1,TCERG1,HMGCR,NEGR1,KIF5A,LSAMP,MYO5A,RASGEF1B,PRKCB,SPDL1,SH3TC2,MSANTD2,KCNIP3,ZFP30,EXOC7,KLHL4,SZT2,TNS1,SLC38A1" MicroRNA hsa-miR-548aw:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-21 7.70E-18 3.30E-21 3.04E-20 50 267 "SPOP,GAS7,STX16,CALM1,PTBP2,EVI5L,CFL2,QKI,DBN1,TMTC1,RCAN2,EPHB1,TAOK3,MED12L,MALT1,RAB30,PRRC2B,GRB10,ELOVL5,AGFG1,ZNF678,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,PPP2R5E,PRKACB,NWD1,SGK1,PEX26,SLC6A8,ATF7IP,KIF13A,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZBTB38,ZNF154,SLC30A4,ZXDA,MFF,STOX2,ITM2C,WNK3,HNRNPA3,FXR1" MicroRNA hsa-miR-6130:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-21 9.23E-18 3.95E-21 3.64E-20 53 301 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA hsa-miR-4419a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-21 9.23E-18 3.95E-21 3.64E-20 53 301 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA hsa-miR-24-2*:mirSVR_highEffct hsa-miR-24-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-21 9.48E-18 4.06E-21 3.73E-20 57 347 "NCKAP5,CC2D2A,SMIM17,ARHGAP20,CCDC146,ZSCAN18,BMPR1B,BTK,CALB1,CALM1,USP2,ZMYM4,SRSF11,ARMC8,CYBB,GAPVD1,RAB39B,DTNB,EMX2,MEX3B,TUBA8,KDM2B,PLCD4,ADAMTS6,GUCY1B1,HAS2,IGF1,MYO9A,NCAM2,VWA2,CHAMP1,PCDH9,TMEM260,ENOX1,OXR1,KCNIP1,TNFRSF19,SCAF8,CPEB4,CDK5RAP2,SNRPN,PDZD2,BDP1,ATP10B,SSTR1,ERBIN,ANKRD28,TCF12,DOCK9,NSD1,SLC44A1,BHLHB9,CLHC1,ZNF711,HNRNPA3,PHTF2,RNF170" MicroRNA hsa-miR-376c-3p:TargetScan hsa-miR-376c-3p TargetScan 1.84E-21 1.03E-17 4.39E-21 4.05E-20 43 197 "KCTD16,ALCAM,PDE8B,NCOA1,DOCK11,CACNA1G,LDLRAD4,CALB1,PTBP2,CBLN1,LRWD1,NRXN3,PYGO1,ELMSAN1,MFAP3L,EDN1,FRY,ANKFY1,FAM49B,GABRG2,PCLO,FRMD3,NKD1,LSAMP,MEIS2,MMP16,ADAM22,PTPRB,PTPRD,GAL3ST4,ROBO1,RORB,SATB1,CPEB3,ABLIM3,CPEB4,LIMCH1,LARP4,DOK6,RGS7BP,KAT6A,NETO2,NETO1" MicroRNA hsa-miR-1911*:mirSVR_highEffct hsa-miR-1911*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-21 1.05E-17 4.47E-21 4.11E-20 66 458 "ZNF608,ALCAM,ZNF687,AMPD3,AMT,MAGEE2,IGDCC4,BCHE,KSR1,C5,CA8,KALRN,HIP1R,CCNH,P2RX6,PLEKHB1,QKI,ARMC8,CLIP3,RUBCN,DTNA,PHC2,PHF20L1,EPHB1,ST3GAL6,STRADA,MED12L,DCTN2,ERGIC3,CELF1,GALC,GATM,STARD3,GPD2,GPR12,PCLO,ZNF496,MAP4K5,FRMD3,ZNF546,ZNF678,MAN2A2,KCTD6,MBOAT7,VPS13C,PTX3,RBBP6,RGS4,ZFHX4,SUGCT,MCMBP,TCP11L1,AP1AR,SCN8A,NUBPL,KANSL3,ERBIN,STAU1,PHLDB1,NSFL1C,KLHL4,DMXL2,SYNE1,SLC44A1,CLHC1,PRTFDC1" MicroRNA hsa-miR-6129:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-21 1.08E-17 4.62E-21 4.25E-20 53 302 "ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,DDR1,HAP1,ARHGEF6,ZNF385A,NCOR2,PITPNM3,IST1,IP6K1,SEC16A,CHRDL1,FGFR1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,SAMD14,NBL1,ZC3H12B,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,POLR2F,NKAIN1,MORC4,KIAA0895L,HES6,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,STX1A,ADAMTS17,ASTN2,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,SIGLEC10,PARP11,ACTR3B" MicroRNA "CCTGTGA,MIR-513:MSigDB" "CCTGTGA,MIR-513:MSigDB" MSigDB 2.08E-21 1.16E-17 4.97E-21 4.57E-20 34 118 "ACHE,MTUS1,OGT,CDC14B,PRX,RUNX1T1,QKI,CRY2,CNTNAP2,PPP1R16B,DMPK,DPYSL2,EYA1,FGFR1,BAIAP2,AGAP2,AGAP3,EVL,USP21,FREM1,PPARGC1A,C1QL4,MAP4K5,NTRK2,MAPK7,TMEM260,SH3GL3,PPM1E,ARHGEF9,SYP,SZT2,RICTOR,MAP3K12,KAT6A" MicroRNA hsa-miR-497-5p:Functional MTI Functional MTI miRTarbase 2.37E-21 1.33E-17 5.67E-21 5.22E-20 66 460 "AXIN2,FZD9,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,CA8,RUNX1T1,CCNT1,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,DMPK,DMTF1,FCF1,HEYL,PLEKHA1,ZNF391,ANKMY1,ZNF585B,MSANTD4,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,CHIC1,MYO5A,OCRL,PDE4D,PIK3R1,PSAT1,PTPRD,RBBP6,ZFHX4,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,TCEA1,DICER1,ZMAT3,TPM1,TPM2,TUBB2A,UBE2H,WNT7A,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-608:PITA hsa-miR-608:PITA_TOP PITA 2.53E-21 1.41E-17 6.04E-21 5.56E-20 36 135 "ASIC1,PITPNM2,SEMA4G,SYNJ1,CABP7,ZMYM4,CABP1,ZNF385A,SH2B1,CLIP3,RAB39B,DMPK,EBF1,EIF4G1,SLC43A2,NRN1,PPP1R1B,AGAP3,SRCAP,SMAP1,LRRTM1,CAMK2N2,GIT1,NEXMIF,NFIX,PDE1B,PSD,TMEM255A,GTDC1,NCBP3,SCN2B,SNAP25,SYP,RPGRIP1L,CBX5,RTN4" MicroRNA "ACAACTT,MIR-382:MSigDB" "ACAACTT,MIR-382:MSigDB" MSigDB 2.84E-21 1.59E-17 6.77E-21 6.23E-20 27 69 "NDRG2,MTUS1,AQP6,EIF4G3,BACH1,CLTC,SEC24C,MATR3,MBNL2,NSRP1,AMOTL2,NEGR1,MBNL1,MMP16,P2RX7,PDPK1,PPP3CC,RPE,SGK1,BTBD7,SYT1,CAMTA1,ZNF106,UBE2H,PLPPR2,SMARCAD1,HPS4" MicroRNA hsa-miR-1914:mirSVR_highEffct hsa-miR-1914:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-21 1.64E-17 6.98E-21 6.43E-20 65 449 "NDRG3,ADCY6,DPY19L2P4,ABCD2,AMPD3,OGT,LCORL,RGS20,LINC00173,ZBTB10,CACNB4,CARS,ENTPD6,CNGA3,CNR1,ENTPD4,CS,RIMS2,BOC,DCAF8,ECM2,E2F5,AASS,EMX2,PIPOX,FGFR1,AMOTL2,ATP2C1,TRAF3IP2,ERAP1,GHR,HPGDS,KIAA1958,GRIA2,INPP5B,KCNN2,MAN2A2,ZNF680,ZNF92,NELL2,PCDH8,DUSP26,RELN,ZMAT4,GTDC1,CCDC82,KLHDC8A,GSTCD,LRRK2,ATXN7,ST6GAL1,ZNF430,SEPHS1,BTBD7,MYO16,SATB2,SLC19A3,AP4E1,ANKRD24,SGK3,NPDC1,ZNF138,UPF3A,KAT6A,SMIM8" MicroRNA "AAAGACA,MIR-511:MSigDB" "AAAGACA,MIR-511:MSigDB" MSigDB 3.20E-21 1.79E-17 7.64E-21 7.03E-20 42 190 "ADGRF5,ALCAM,PCDH10,AQP6,SPTBN4,ATP2B2,CALM1,CDH2,FOXN3,NRXN3,CLTC,QKI,MAP4K4,CREM,C1QL2,RPS6KL1,DCTN4,EYA1,FGF13,CELF1,MSTN,PCDH17,PPARGC1A,TNRC6A,HAS2,HLF,CNOT4,NTRK2,KHDRBS2,REV3L,ROBO2,SEMA6D,CDK19,SS18,RGL1,CAMTA1,SATB2,TRIM2,UBE2H,CFAP298,FIP1L1,ADAMTSL3" MicroRNA hsa-miR-4659a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.38E-21 1.89E-17 8.06E-21 7.42E-20 46 230 "RALGAPA1,SPOP,TNRC6C,ARSE,CDK13,CALM1,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,TENM1,STARD3NL,COQ7,DLC1,GORAB,PCDH17,HAS2,NEGR1,SYTL4,LSAMP,SRSF12,SAMD5,NOVA2,NPTX2,FAM98B,PLCL1,PRKCB,SH3TC2,TMLHE,TRAPPC13,SEMA6D,CSRNP3,BDP1,SSTR2,MPRIP,DIP2A,FAM208A,TBL1X,ASXL3,TLR4,TNS1,RPL7L1,UGT8,ZDHHC20" MicroRNA hsa-miR-4659b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.38E-21 1.89E-17 8.06E-21 7.42E-20 46 230 "RALGAPA1,SPOP,TNRC6C,ARSE,CDK13,CALM1,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,TENM1,STARD3NL,COQ7,DLC1,GORAB,PCDH17,HAS2,NEGR1,SYTL4,LSAMP,SRSF12,SAMD5,NOVA2,NPTX2,FAM98B,PLCL1,PRKCB,SH3TC2,TMLHE,TRAPPC13,SEMA6D,CSRNP3,BDP1,SSTR2,MPRIP,DIP2A,FAM208A,TBL1X,ASXL3,TLR4,TNS1,RPL7L1,UGT8,ZDHHC20" MicroRNA "CCTGCTG,MIR-214:MSigDB" "CCTGCTG,MIR-214:MSigDB" MSigDB 3.51E-21 1.96E-17 8.35E-21 7.69E-20 45 220 "ADORA2A,MARK4,JAZF1,CACNA1I,NRXN3,QKI,IGDCC3,CRY2,CSF1,SEC24C,RIMS4,MYEF2,DNAJB6,PHC2,YAF2,EIF4G1,EZH1,AFF2,PCDH17,SHISA6,KIFC3,PIK3AP1,MAPT,MID1,NBL1,GPR85,RETREG2,SEPT4,OXR1,DUSP15,ARMC5,SALL1,MYO18A,ABLIM3,CPEB4,ZHX3,IQSEC2,CAMTA1,CLASP1,DOCK9,TRPM2,TRPS1,KLC2,PCDH20,ZIC1" MicroRNA hsa-miR-1257:PITA hsa-miR-1257:PITA_TOP PITA 3.57E-21 2.00E-17 8.51E-21 7.83E-20 41 181 "UNC5A,CADPS,SPAG9,USP6,DLGAP2,FOXN3,NRXN3,CLTC,QKI,CREM,FAM13A,PAN3,MSTN,CIT,SMAP1,ZIC5,IPO5,SFXN5,MXI1,MYO6,PIK3C2A,PTPRD,DPF2,REV3L,SEMA6D,CSRNP3,PPM1E,CPEB3,NLGN1,CCDC88A,PDZD2,MYCBP2,LMO3,POGZ,SEPT8,DMXL2,CBX5,TBC1D15,WIPF1,EMSY,HNRNPA3" MicroRNA hsa-miR-548f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.68E-21 2.06E-17 8.75E-21 8.06E-20 49 262 "SPOP,STX16,CALM1,PTBP2,EVI5L,CFL2,QKI,UBXN2A,DBN1,TMTC1,RCAN2,TAOK3,MED12L,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,LAMP2,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,CNNM2,NWD1,SGK1,PEX26,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-1182:PITA hsa-miR-1182:PITA_TOP PITA 3.78E-21 2.12E-17 9.00E-21 8.29E-20 34 120 "KCNH8,ASIC1,SYS1,PCDH19,CACNA2D1,CAMK2G,DCLK1,SEC24C,ERC2,TAOK3,USP21,RNF165,ADAMTS6,ZHX1,NKD1,ZIC5,MEF2C,OLA1,KANSL1,MAPK10,RELN,RBBP6,RGS4,STX1B,SST,SYP,SYPL1,KAT6B,EIF4ENIF1,MKRN3,SLC38A1,WNK3,KAT6A,ADAMTS10" MicroRNA hsa-miR-1203:mirSVR_lowEffct hsa-miR-1203:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.97E-21 2.22E-17 9.44E-21 8.69E-20 57 353 "SUGT1P4-STRA6LP-CCDC180,PKP4,PPFIA3,SLC2A11,TTLL9,ARHGEF7,CA4,KALRN,ZNF385A,RUBCN,EARS2,DOCK2,RCAN1,EDN3,HIPK3,EBI3,SLC43A2,SRRM1,POLR1B,AGAP3,SEMA4D,WDR83,APOPT1,CGREF1,DOT1L,ZNF274,TUBA8,ADGRA3,CCDC184,ZBTB49,C2orf72,KCND1,LAMP2,PACRG,MYO7A,CCDC13,PAX6,GNG2,PURG,PMP22,SDK2,DEF8,ZNF331,MAPK12,SEC14L1,MGRN1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RUSC1,FBXO36,CASC15,JPH3" MicroRNA hsa-miR-939-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-21 2.27E-17 9.64E-21 8.87E-20 64 439 "AS3MT,SLC24A4,HACE1,PRX,ARSE,SLC4A4,CBS,SLC16A4,ZNF445,DIS3L,NRG2,CSNK1E,SUSD5,UBXN2A,GAPVD1,CENPL,ZBTB24,RUSC2,MTX3,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,ANKFY1,TRMO,FUT9,CRCP,GPR75,KDM2B,LILRA2,DDX19B,ITPKB,KCNN3,SAMD5,SLC11A2,PIK3R1,MTRF1L,TATDN3,FITM2,APTX,PEX2,ZSCAN2,GTDC1,KLHL11,KLHDC8A,STX1B,ZNF331,FAM192A,BDP1,ADAMTS17,ALG1,AGTPBP1,ARL10,CBX5,PARD3,PPIL6,SSBP2,UBC,TBC1D15,KLC2,TRIM16L,RNF170" MicroRNA hsa-miR-489-3p:TargetScan hsa-miR-489-3p TargetScan 4.07E-21 2.28E-17 9.68E-21 8.91E-20 46 231 "KLHL32,PKP4,DST,LURAP1,CALM1,LONRF2,NRXN3,CLOCK,KATNAL2,MATR3,JAKMIP2,MTX3,DLX1,FEM1B,IGSF6,EYA1,MRVI1,GNAL,PRDM5,HAS2,FRMD3,KCNN2,IPO5,PACRG,MMP16,DBNL,HS6ST3,MXI1,NOVA2,PAX6,PDE1B,CEP41,PEX2,RORB,FBXW7,GLDN,CSRNP3,FNIP1,CPEB3,CHD9,HECW1,MYCBP2,NACC2,CBX5,CADM2,FZD3" MicroRNA hsa-miR-184:mirSVR_highEffct hsa-miR-184:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.25E-21 2.38E-17 1.01E-20 9.29E-20 45 221 "KIAA1211,KCTD16,PCDH10,SUGT1P4-STRA6LP-CCDC180,EPB41L5,MARCH3,CCAR2,CAMK2B,VXN,TAOK2,CNGA3,ANKRD44,ARHGEF10,ARHGAP24,DPP6,DTNA,ELN,EPB41L2,NRN1,ZNF589,FGF14,SCARA3,WDR83,AKAP3,UFM1,B4GALNT1,MAT2A,MBP,NRCAM,PDE4B,PLTP,APTX,WDR25,RNASEL,MEG3,SLA,SLC11A1,ADHFE1,SULF2,TMEM150C,SYPL1,CUX2,ZFPM2,LRRC8A,MEIS3" MicroRNA "AAAGGGA,MIR-211:MSigDB" "AAAGGGA,MIR-211:MSigDB" MSigDB 4.30E-21 2.41E-17 1.02E-20 9.39E-20 44 211 "ADCY6,AP2A2,KLHL13,SPOP,KALRN,USP6,CDC25B,CDH2,CCPG1,SOCS6,CHN2,GAPVD1,DMTF1,FRY,CELSR3,APH1A,ING4,RPS6KC1,SLC37A3,NBEA,KHDRBS3,GABRB3,FREM1,PPARGC1A,STXBP5,NCOA7,MBNL1,KITLG,NOVA1,NPTX1,NTRK2,PCDH9,XRN1,FBXW7,SOX11,ZNF423,SATB2,TCF12,SIRT1,RICTOR,ADAMTS9,SLC17A7,ST7,JPH3" MicroRNA "AAAGGGA,MIR-204:MSigDB" "AAAGGGA,MIR-204:MSigDB" MSigDB 4.30E-21 2.41E-17 1.02E-20 9.39E-20 44 211 "ADCY6,AP2A2,KLHL13,SPOP,KALRN,USP6,CDC25B,CDH2,CCPG1,SOCS6,CHN2,GAPVD1,DMTF1,FRY,CELSR3,APH1A,ING4,RPS6KC1,SLC37A3,NBEA,KHDRBS3,GABRB3,FREM1,PPARGC1A,STXBP5,NCOA7,MBNL1,KITLG,NOVA1,NPTX1,NTRK2,PCDH9,XRN1,FBXW7,SOX11,ZNF423,SATB2,TCF12,SIRT1,RICTOR,ADAMTS9,SLC17A7,ST7,JPH3" MicroRNA hsa-miR-548aj-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-21 2.44E-17 1.03E-20 9.52E-20 49 263 "SPOP,STX16,CALM1,PTBP2,EVI5L,CFL2,QKI,UBXN2A,DBN1,TMTC1,RCAN2,TAOK3,MED12L,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,LAMP2,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,CNNM2,NWD1,SGK1,PEX26,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-548g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-21 2.44E-17 1.03E-20 9.52E-20 49 263 "SPOP,STX16,CALM1,PTBP2,EVI5L,CFL2,QKI,UBXN2A,DBN1,TMTC1,RCAN2,TAOK3,MED12L,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,LAMP2,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,CNNM2,NWD1,SGK1,PEX26,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-548x-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-21 2.44E-17 1.03E-20 9.52E-20 49 263 "SPOP,STX16,CALM1,PTBP2,EVI5L,CFL2,QKI,UBXN2A,DBN1,TMTC1,RCAN2,TAOK3,MED12L,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,LAMP2,MBNL1,CHIC1,ZNF680,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,CNNM2,NWD1,SGK1,PEX26,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-365a-3p:TargetScan hsa-miR-365a-3p TargetScan 4.48E-21 2.50E-17 1.06E-20 9.76E-20 51 285 "ADCY6,PTCHD1,PITPNM2,PHF12,RGS20,ARRB2,RNF182,PTBP2,DLGAP2,NCOR1,CS,DOCK4,GAPVD1,HDAC4,NR1D2,DTNA,RGS17,ETV1,MED12L,FGF1,MALT1,RASSF8,HMGCR,NKD1,KCNH2,LAMP2,LRP1B,MEIS1,P2RY1,PAX6,PCDH8,PCSK5,PDE4D,KANSL1,PPP5C,GRAMD1C,DPF2,REV3L,ROBO1,SALL1,ATXN7,CHD9,EPC1,KDM3A,PEG10,ANKRD28,SATB2,CSMD1,NR2C2,RICTOR,FZD3" MicroRNA hsa-miR-365b-3p:TargetScan hsa-miR-365b-3p TargetScan 4.48E-21 2.50E-17 1.06E-20 9.76E-20 51 285 "ADCY6,PTCHD1,PITPNM2,PHF12,RGS20,ARRB2,RNF182,PTBP2,DLGAP2,NCOR1,CS,DOCK4,GAPVD1,HDAC4,NR1D2,DTNA,RGS17,ETV1,MED12L,FGF1,MALT1,RASSF8,HMGCR,NKD1,KCNH2,LAMP2,LRP1B,MEIS1,P2RY1,PAX6,PCDH8,PCSK5,PDE4D,KANSL1,PPP5C,GRAMD1C,DPF2,REV3L,ROBO1,SALL1,ATXN7,CHD9,EPC1,KDM3A,PEG10,ANKRD28,SATB2,CSMD1,NR2C2,RICTOR,FZD3" MicroRNA hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 4.91E-21 2.75E-17 1.16E-20 1.07E-19 61 403 "RNF150,NME5,ALCAM,TRMT9B,APBA2,APBB2,CPNE5,STX16,MYOM1,CLCN3,SUMF2,CSF1,CYBB,MTX3,SLC25A18,FRY,EPB41,ENPP6,SYNCRIP,IQCG,SARAF,NEURL4,TUBA8,GDF9,TNRC6A,ADAMTS6,IGFBPL1,ZDHHC15,ZIC5,CDH20,KCNJ16,MATN3,CNOT4,NPTX1,MTMR10,KHDRBS2,RFX3,GSTCD,CCDC92,FAM81A,BTBD3,BTBD7,MAST1,USP33,SOX11,CDK19,ATP10B,LARP4,SYNE2,TACC1,FBXW11,SYNE1,DICER1,AP4E1,PDSS1,UGT8,OSBP2,TOM1L2,RTN4,FXR1,CPNE4" MicroRNA hsa-miR-550:mirSVR_highEffct hsa-miR-550:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.31E-21 2.97E-17 1.26E-20 1.16E-19 75 587 "ABCF1,ADD2,BEND6,RTL9,OSBPL8,FAM135A,IGDCC4,CDK13,SPAG9,CCNH,MTMR7,CD86,DLGAP1,PPT2,NGEF,ARMC8,AKAP5,AHCTF1,SNCAIP,DOCK4,DGKB,DAPK1,BRINP1,GIT2,B3GAT3,DLX1,PDCD6IP,YAF2,RGS17,EMX2,GPHN,FGF1,SCARA3,STAU2,AP4B1,DOT1L,TRAF3IP2,INPP5K,RAB30,KCNMB4,PSIP1,ADAMTS6,IL6ST,KCNN2,ASPRV1,MAP4,MAT2A,LRP1B,PPM1L,NLGN3,TMEM38A,PCDH18,SCHIP1,FSD1,PPP2R5E,EPDR1,DIRAS2,STK32A,FAM66C,GTDC1,PTGR2,ST6GALNAC6,RCOR3,ERBIN,ADGRL3,KLHL4,MTMR14,TPM1,NPL,SYNPO2,TSC1,RPL7L1,TRIM9,EML6,RNF170" MicroRNA hsa-miR-665:TargetScan hsa-miR-665 TargetScan 6.04E-21 3.38E-17 1.43E-20 1.31E-19 57 356 "RNF157,OGT,CCDC74A,CCAR2,CABP7,HAP1,CBFA2T2,CDR1,RAB26,PCYT1B,GDA,RIMS4,DGKG,PHC2,CNNM1,HEYL,ELN,ENO2,MTSS1L,ENPP6,CORO2B,FCGRT,FGFR1,AGAP2,B4GALNT1,BTN2A1,FICD,FRMD3,KCNB1,KCNN3,ADAM11,DBNL,FXYD7,NNAT,PALM,PDPK1,GNG2,RASGEF1B,MAPK4,PTPRB,DPF2,ALG9,FAM102A,MYO18A,CCDC92,PKNOX2,RADIL,NSD1,ARHGAP9,CRTC1,CBX5,DOK6,LGI4,POLR3H,GDPD5,KAT6A,GAN" MicroRNA hsa-miR-183:PITA hsa-miR-183:PITA_TOP PITA 6.12E-21 3.43E-17 1.45E-20 1.33E-19 49 265 "OSBPL8,PKP4,SRSF11,SOCS6,CLCN3,AKAP12,CSNK1G3,KLHL3,RHOBTB1,SACS,YAF2,GOLGA7,MRVI1,CLVS1,SUCO,SESN1,KDM2B,GNG4,MAP4K5,BACH2,HLF,ICA1,SOWAHA,KCND2,KIF2A,MBNL1,MEF2C,PDE4D,MAPK4,SLC25A36,CYB561D1,ROBO2,CLIP1,SMPD3,PPM1E,TET1,LMO3,ERBIN,TCF4,CUX2,TCF12,FRYL,ZFPM2,SLC44A1,TIAM1,RIMBP2,CSMD1,TPM1,FRMD6" MicroRNA hsa-miR-4779:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-21 3.45E-17 1.46E-20 1.34E-19 51 287 "XKR4,ADD2,MTUS1,SORCS2,TRMT9B,PHF12,SEMA4G,ARRB1,CACNA2D2,TMEM184B,SEC16A,CHRDL1,TNK2,MTSS1L,KATNAL1,AMOTL2,BRSK1,CRCP,GLYR1,GRIN2D,ZBTB49,SHISA6,NKD1,STMN1,PPM1L,MPP2,SAMD14,NBL1,ZC3H12B,NELL2,NOVA2,PDE4A,POLR2F,PPARA,PPP2R2B,TMEM231,IQSEC3,ALG9,HES6,TRIM67,UNC5B,CAMTA2,ASTN2,NACC2,ASXL3,BCL2L13,INTS3,URM1,ITM2C,PARP11,ACTR3B" MicroRNA hsa-miR-6809-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.19E-21 3.46E-17 1.46E-20 1.35E-19 54 321 "RNF157,MTA3,MARCH4,PARG,USP37,PTCH2,GPR146,CAMK2G,CD86,CST3,PITPNM3,ZSCAN23,GAPVD1,MAML1,C2CD2L,CDON,EDN3,RGS17,EMX2,CELF1,GALC,GATM,SULT1C4,PTPRT,NEGR1,IL6R,GPR155,NFIX,NOVA2,NPTX1,P2RX7,PLCL1,PKIA,PRKCB,SNRK,PTPRN2,ZSCAN2,FIGN,TMLHE,CSRNP3,SGK1,CPEB3,CHD9,ZNF667,ZNF415,RBM26,TROVE2,TNS1,SGK3,ZNF23,DHX33,CADM2,PRDM10,MPPE1" MicroRNA hsa-miR-1256:PITA hsa-miR-1256:PITA_TOP PITA 6.24E-21 3.49E-17 1.47E-20 1.36E-19 37 147 "PCDH19,ALCAM,OGT,DPP10,BCL7A,SYNJ1,CPNE6,CNR1,CNTFR,HDAC4,E2F5,EIF1,EYA1,FRMD3,AGFG1,ZIC5,MAT2A,NEXMIF,ZC3H12B,NFIX,PCDH9,PDZRN4,TMEM255A,NUDT11,RXRA,SALL1,SGK1,KDM4B,STAC2,SYNE2,ANKRD28,DMXL2,NR2E1,CSMD1,FLRT2,HNRNPA3,PHTF2" MicroRNA hsa-miR-181a*:mirSVR_lowEffct hsa-miR-181a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.64E-21 3.71E-17 1.57E-20 1.44E-19 53 310 "GALNT13,SORCS2,ARHGAP20,CDC14B,ARHGDIA,ARNTL,BMP7,CABP7,CALM1,MS4A7,GREB1,KCTD8,INTS1,DGKB,DGCR5,EXOG,FRY,CORO2B,GORAB,AFF2,FLYWCH1,CELF1,GABBR1,DISC1,STON1,MCHR1,ADAMTS13,SMAP1,KCNN3,LIG4,SMAD1,ZFYVE27,NEFM,NF1,SLC11A2,RETREG2,CCDC144B,RIC8B,ROBO2,SEC14L1,SEPHS1,CPEB4,CDK5RAP2,ANKRD36,JMJD6,TACC1,TAL1,SATB2,SYNPO2,OSBP2,VLDLR,ACTR3B,FAM219B" MicroRNA hsa-miR-1278:PITA hsa-miR-1278:PITA_TOP PITA 6.88E-21 3.85E-17 1.62E-20 1.49E-19 41 184 "KLHL13,TAOK1,PITPNM2,PPFIA4,EIF4G3,DPY19L3,RUNX1T1,SH2B1,KIAA0408,MYEF2,EDIL3,YAF2,ELN,GPHN,EYA1,FOXO3,FUT9,RNPS1,PRRC2B,GRIA2,GUCY1A1,AGFG1,IPO5,MAP4,MN1,NEFM,OLA1,SCHIP1,TTC13,ZNF532,ROBO1,RTN1,SEMA6D,PKNOX2,SMARCA4,ERBIN,PRRC2C,TCF12,AKTIP,TBC1D15,TIGD6" MicroRNA hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 7.15E-21 4.00E-17 1.69E-20 1.55E-19 63 431 "APC,BACH1,BMPR1B,MTMR3,SLC16A4,LONRF2,ZNF385A,NCOR2,RIMS4,MATR3,IP6K1,MYEF2,RASGRP1,SUGP2,EGFR,EIF5,ERBB2,CD320,C2orf88,SMC2,GABRB3,ACSS1,MUM1,MAN1B1,NEGR1,IL6R,JAK2,SLC35G1,LIFR,LSS,PTOV1,NTRK3,OPRL1,PKM,MTRF1L,STRN3,PSAT1,DRAM2,PTH1R,C1orf109,HKR1,UBR7,RNH1,CASC3,COPZ1,R3HDM2,BTBD3,ABTB1,EXOC7,FAM208A,PCDHGB2,CRTC1,TMEM9,HSPBP1,SLC35A4,BCL2L13,KLC2,ZNF177,DHX33,STOX2,SMIM8,TMEM63C,FXR1" MicroRNA hsa-miR-3135b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.54E-21 4.22E-17 1.78E-20 1.64E-19 60 394 "ABCF1,AS3MT,XKR4,RNF157,ESYT2,ISPD,ENTPD4,CSF1,DBT,KRBA2,E2F6,HEYL,OPTN,TUBD1,SEC23B,CINP,SPECC1,SRCAP,GPR75,PRRC2B,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,ZFYVE27,MKLN1,MMP17,MYCN,ZNF713,GPR137C,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,ROBO1,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,ANKRD36,ERC1,SSTR2,MPRIP,APOM,KLHL7,ALG1,GPRIN3,GPR161,ZNF34,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2" MicroRNA hsa-miR-657:PITA hsa-miR-657:PITA_TOP PITA 7.59E-21 4.24E-17 1.79E-20 1.65E-19 40 175 "USP31,INTS2,KIAA1324,OSBPL8,CDC14B,SLC4A4,KIF1A,MAGI1,CCPG1,FOXN3,QKI,TBPL1,ERC2,TAOK3,NBEA,GABRG2,ARFIP1,AHDC1,DCLK2,KAT7,BACH2,MAP4,MAPT,MEF2C,ZC3H12B,ZNF827,PID1,FIGN,CSRNP3,GALNT10,CCDC92,SEPHS1,ZNF423,CAMTA1,TRPS1,VSNL1,ZIC1,EMSY,PPP1R3F,KCNAB1" MicroRNA hsa-miR-647:PITA hsa-miR-647:PITA_TOP PITA 7.59E-21 4.24E-17 1.79E-20 1.65E-19 40 175 "SPOP,ALCAM,NCOA1,ADGRB1,KALRN,CAMK2G,DCLK1,ZNF521,IGDCC3,SH2B1,PDE4DIP,LYPD1,CPEB2,DPYSL2,FAM78B,PHC2,EGR3,TMEM35A,DNAJC27,CLVS1,TNRC6A,GRIA2,RNF165,KPNA5,GIT1,NFIX,NOVA1,ZNF827,WBP1L,PTPRB,DUSP15,GTDC1,ZFHX4,ELMO2,SOX11,POGZ,SS18,STX1A,R3HDM1,TRPS1" MicroRNA hsa-miR-361-5p:TargetScan hsa-miR-361-5p TargetScan 7.74E-21 4.33E-17 1.82E-20 1.68E-19 44 214 "BEND6,MTUS1,ARHGAP20,DPP10,PKP4,CBFA2T2,CFL2,B4GALT6,RCHY1,ERC2,MTX3,CALCRL,EPB41,RCAN2,GPHN,ERBB4,RRAGB,ANKFY1,FUT9,GPR75,PRUNE2,HMGCR,KCNN1,KIF5A,GPR155,MAP2,MXI1,ALDH1L2,NFIX,PDE4B,PIK3R1,PKIA,PTPRG,GTDC1,EXD2,ALG9,SCAF8,BDP1,FNBP1,CDK19,KLHL7,CSMD1,LYPD6,PARP11" MicroRNA hsa-miR-1537:mirSVR_highEffct hsa-miR-1537:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.84E-21 4.39E-17 1.84E-20 1.70E-19 56 346 "ADCY8,BRAP,PWWP2A,AMPH,TNRC6C,USP37,TTLL9,BCHE,BMP7,ARHGEF2,QKI,RIPOR2,KIAA0586,GIT2,SNAP91,SPOCK3,DPYSL2,DTNA,YAF2,EIF1,TUBB3,FGF13,EVL,CHL1,GCNT2,ARFIP1,ZNF638,GNAO1,UBE2QL1,IL6R,ZNF678,SMAD1,LRP1B,PCSK5,PPM1B,SGK1,WDR47,PDZRN3,LMO3,ATP10B,POGZ,ADHFE1,ADGRL3,ITGB3BP,AKTIP,RIMBP2,ELP5,TRO,WIPF1,KLC2,ANKS1B,UPF3A,EMSY,ITM2C,PDSS2,PHTF2" MicroRNA hsa-miR-584:PITA hsa-miR-584:PITA_TOP PITA 8.53E-21 4.77E-17 2.01E-20 1.85E-19 41 185 "OSBPL6,USP37,CADPS,LDLRAD4,RUNX1T1,B4GALT6,AKAP6,MYRIP,NCOR1,RGS6,PUM1,GAPVD1,USP3,FAM78B,E2F5,ERBB4,ACSL4,MEX3B,HSF2,KIF2A,MAP2,MEIS2,SCAMP5,MITF,MXI1,NEXMIF,NF1,OLA1,TTC13,ZNF493,REV3L,SETD5,FBXW7,CNKSR2,HECW1,FBXW11,DOK6,STXBP4,FLRT2,TBC1D15,ZIC1" MicroRNA hsa-miR-27b-3p:Functional MTI Functional MTI miRTarbase 9.86E-21 5.51E-17 2.32E-20 2.13E-19 62 421 "ADD1,FZD9,KIAA1211,OSBPL6,TAOK1,SEMA6A,ARNTL,MTMR3,HIP1R,SPAG9,CCNT1,SOCS6,CNN3,RGS6,LONRF1,LIN54,ELMO1,C2CD2L,ZC3H11A,SEC16A,NR1D2,EDNRA,PHC2,FEM1B,TMTC1,EGFR,EIF5,GTF2IRD2,SUCO,CELF1,OGA,SRCAP,MIER3,SLC6A17,LIFR,PAXBP1,NF1,NFE2L2,RETREG2,MAPK9,BDNF-AS,RET,ALG9,SEMA6D,COPZ1,FNDC3A,CPEB4,ZFP1,ERC1,PEG10,TROVE2,POGZ,MPRIP,NSD1,FRYL,ZNF106,RGMB,TTC3,ZNF45,MFF,AP3B2,SPATA13" MicroRNA hsa-miR-562:PITA hsa-miR-562:PITA_TOP PITA 1.02E-20 5.69E-17 2.39E-20 2.20E-19 39 167 "ZNF608,PCDH19,ARHGAP20,AMPD3,SEMA7A,ZBTB10,NCOA1,ATP2A2,ZMYM4,HECTD1,AKAP5,MATR3,ELMSAN1,MEX3B,SYNCRIP,GHR,PPARGC1A,KCNMB4,PSIP1,IGF1,CHIC1,RELN,PTPRG,SH3TC2,RDX,FIGN,PPM1E,SLC12A2,MYO16,SOX3,ZBTB43,CLASP2,NKAIN2,NECAB1,PRRC2C,TRIM2,TPM1,UBE3A,SMIM8" MicroRNA "TAATGTG,MIR-323:MSigDB" "TAATGTG,MIR-323:MSigDB" MSigDB 1.03E-20 5.77E-17 2.42E-20 2.23E-19 37 149 "ARHGAP20,FAM135A,PKP4,NT5C3B,PPP4R4,SLC4A4,CLCN3,MAP4K4,TBPL1,CSNK1G3,FEM1B,EGR3,PTK2B,SPSB4,SUCO,ARFIP1,PPARGC1A,TNRC6A,ADAMTS6,ZHX1,NFIX,PCDH9,ANKHD1,DPF2,REV3L,SEMA6D,SATB1,CPEB4,NKAIN2,SEPT3,CAMTA1,RPGRIP1L,CLASP1,TMPO,WBP2,ZIC1,SMARCAD1" MicroRNA hsa-miR-1205:PITA hsa-miR-1205:PITA_TOP PITA 1.09E-20 6.11E-17 2.56E-20 2.36E-19 45 226 "ASIC1,ADCY6,CCDC85A,AMPH,SLC4A4,KIF1A,CACNA1A,HAP1,CAMK2G,RUNX1T1,CNTFR,SNPH,TMEM132E,TENM1,GPHN,BRSK1,ARFIP1,TNRC6A,KCND2,MBD1,MEF2C,MSI1,MYO7A,CNOT4,CCSER2,RETREG1,TMEM260,RIPOR1,SEMA6D,SATB1,PRCD,BTBD3,SOX11,NMNAT2,ASTN2,MCF2L,FBXW11,RPGRIP1L,FRYL,PCDH20,LAMP5,ZFAND5,SLC30A4,GDPD5,WNK3" MicroRNA hsa-miR-149-5p:Functional MTI Functional MTI miRTarbase 1.11E-20 6.21E-17 2.61E-20 2.40E-19 60 397 "CLK4,TBC1D14,OSBPL8,ARRB2,CCAR2,KIF1A,BID,CBS,LRRFIP1,ARHGAP22,ZNF385A,LRIG1,CSNK1E,PPP6R2,MATR3,DBN1,ELMSAN1,EEF1D,EIF5,DCTN4,FDFT1,FGFR1,AGAP3,DCTN2,GFER,ZNF276,RNPS1,TOX3,GLUL,IBA57,MID1,GIT1,NACA,NFIX,NPTX1,PDE1B,FAM98B,FAM216A,KANSL1,RBBP6,RGS12,LGI2,RPL15,SBF1,PEX26,DHX30,CDK5RAP2,ZSWIM8,ZNF621,SUPT5H,PRRC2C,SATB2,OBSL1,NSD1,LRRC8A,ZNF346,ZNF610,SPHK2,TMEM237,FXR1" MicroRNA hsa-miR-154:PITA hsa-miR-154:PITA_TOP PITA 1.12E-20 6.29E-17 2.64E-20 2.43E-19 42 196 "USP31,INTS2,MTUS1,OSBPL8,LCORL,TMEM108,CAMK2G,FOXN3,NRXN3,SLC35F1,SOCS5,E2F5,GABRG2,B4GALNT1,SRRM4,GATM,LUZP2,STON1,KAT7,NEGR1,SOWAHA,MEF2C,CNOT4,NTRK2,MINDY2,GDPD1,TMEM255A,GTDC1,SALL1,FNIP1,PPM1E,CPEB3,PPP4R3A,PKNOX2,SP4,CUX2,TCF12,TIAM1,CLDND1,CADM2,EVI5,FXR1" MicroRNA hsa-miR-582-3p:PITA hsa-miR-582-3p:PITA_TOP PITA 1.17E-20 6.52E-17 2.73E-20 2.52E-19 48 258 "RTL9,OSBPL8,JAZF1,CACNB4,SEPT7,ZMYM4,NOG,FOXN3,FAM19A5,LONRF1,AIF1L,LYPD1,DPH1,FAM13A,FOXO3,PCDH17,TNRC6A,FERMT2,PCLO,CIT,MIER3,MAP2,MAPT,MAT2A,PDE4D,PDZRN4,TTC13,ENOX1,RDX,PBRM1,SPIN3,CHD9,NLGN1,TMCC1,CLASP2,RGL1,TBL1X,TCF4,PUM2,FRYL,R3HDM1,TRPS1,TSN,WIPF1,KCNT2,SMARCAD1,NAV3,KAT6A" MicroRNA hsa-miR-662:mirSVR_lowEffct hsa-miR-662:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-20 6.69E-17 2.80E-20 2.58E-19 64 448 "RNF157,MTA3,SUGT1P4-STRA6LP-CCDC180,APBA2,SLC2A11,ADAM23,ADAM15,SYNJ2,CALB2,USP6,RAB33A,TPP1,SLC4A8,ARHGEF10,CNTNAP2,KATNAL2,KIF26A,DCTN1,MFAP3L,DMPK,EBI3,TUBB3,ATP13A4,FLT1,DCTN2,WDR83,KHDRBS3,LRRC37A6P,CPLX2,ARFIP1,ADAM28,GGT7,FAM107A,FAM222A,MBP,CHIC1,PPM1L,GIT1,NTRK2,PIK3R1,ZFYVE21,PNMA3,SDK2,SEPT4,POU6F1,LRRN3,WBP1L,BDNF-AS,RGS12,MEG3,SCP2,ZFP30,AMBRA1,EPN2,SLC6A8,NKAIN2,TAL1,TNS1,TRIO,UBE3A,MGAT5B,SPIRE1,MEIS3,JPH3" MicroRNA hsa-miR-1249:mirSVR_lowEffct hsa-miR-1249:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-20 6.78E-17 2.84E-20 2.61E-19 53 314 "DGCR6,ADGRF5,CDK13,MARCH3,KALRN,CBLN1,P2RX6,L3MBTL4,MAGI1,RAB28,MAP4K4,COX4I1,SMARCAL1,RGS6,ARHGEF10,DOCK4,HDAC9,TIAM2,SACS,DNM1L,E2F5,PHC2,FRY,PHF20L1,FCGR1A,GORAB,MEX3B,AGAP2,NOP56,AKAP3,KHDRBS3,SEPT9,DCLK2,SPACA9,GRIK4,FRMD3,IL12A,KHK,LINC00634,MSI1,SFR1,CNOT4,PKIA,PIGG,RGS3,CSRNP3,NUBPL,CXXC4,IFT122,CLSTN2,THRA,FAM155A,OSBP2" MicroRNA hsa-miR-1248:PITA hsa-miR-1248:PITA_TOP PITA 1.22E-20 6.83E-17 2.86E-20 2.63E-19 46 237 "JAZF1,LDLRAD4,CAMK2G,SOCS6,CLCN3,CSNK1G3,CNTNAP2,RIMS2,GAPVD1,BRINP1,ELMSAN1,CPEB2,PDCD6IP,ENPP6,EYA1,DLC1,AGAP3,PRELID3A,PCDH17,ADAMTS6,KTN1,ADAM11,MEF2C,MYO5A,NOVA1,ZNF827,PDE1B,GPR85,RFX3,FBXW7,NCBP3,FAM214B,FAM126B,SOX11,HECW1,MYCBP2,SSTR1,ZSCAN29,PRRC2C,TBL1X,TIAM1,TRPS1,TMEM237,NAV3,PDSS2,ST8SIA2" MicroRNA hsa-miR-423-3p:mirSVR_lowEffct hsa-miR-423-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-20 7.06E-17 2.95E-20 2.72E-19 60 398 "ADRB2,CARNS1,AMPD2,LRFN1,PHF12,CDK10,ATP1B3,CA8,USP6,DLGAP1,LYPD1,USP3,DNAH9,CD99L2,CDON,DMTF1,DPYSL2,EDN1,EDNRA,EIF4G1,EPHB1,CD320,ZNF589,PRKAG2,MEX3B,SLC37A3,DISC1,GCNT2,ZNF638,LOXL3,LAMP2,GIT1,PTOV1,DNHD1,IGSF11,POLR2F,POU6F1,MAPK7,PTK2,STK32A,NKAIN1,MRPS18A,ATAT1,CCDC92,PKNOX2,SLC14A1,ARFGAP1,CDK5RAP2,MAPKBP1,SSPO,NSFL1C,JMJD6,DOCK9,TIAM1,TMPO,VLDLR,KLC2,TMEM237,FIP1L1,PDSS2" MicroRNA hsa-miR-1539:mirSVR_lowEffct hsa-miR-1539:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-20 7.58E-17 3.17E-20 2.92E-19 58 374 "FAHD2CP,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,ZFYVE28,ADAM23,ADAM15,DDR1,DGCR9,CNRIP1,NCOR2,CCDC144A,TBC1D5,DMTF1,ENO2,PPP1R1B,IP6K2,NELFCD,RASL10A,NEURL4,HRASLS5,FAM120B,GCK,GGT5,ZNF638,KCNMB4,ADAMTS13,GRIK5,ZBTB45,DISP2,GPR155,PPM1L,MXI1,NNAT,DNHD1,PCBP3,SEMA5B,PNMA3,SCHIP1,PRKAB2,ZCWPW1,RIC8B,ARMC5,PRCD,SH3BP2,SHMT2,RADIL,ARFGAP1,STAU1,PHF24,FAM189A1,CHST5,ZNF346,RUSC1,TSC1,LAT2,SEMA3B,PDSS2,HNRNPA3" MicroRNA hsa-miR-338-3p:PITA hsa-miR-338-3p:PITA_TOP PITA 1.38E-20 7.71E-17 3.22E-20 2.97E-19 44 217 "TMEM132B,ESYT2,MTUS1,SEMA6A,MAP4K3,ZBTB10,CACNB4,THSD7A,CNR1,CNTFR,RGS6,DGKB,DNAJB6,FRY,PLEKHA1,PAN3,AFF2,CHL1,CPLX2,GRIA2,FRMD3,NCKAP1L,BACH2,KCND2,MAP2,NOVA1,XRN1,PRKCB,TMEM255A,ZFHX4,FBXW7,CPEB3,MBD5,MYCBP2,LMO3,CLASP2,LARP4,PRRC2C,SYN2,TSC1,TBC1D15,CADM2,RGS7BP,FZD3" MicroRNA "TTTGCAG,MIR-518A-2:MSigDB" "TTTGCAG,MIR-518A-2:MSigDB" MSigDB 1.38E-20 7.72E-17 3.22E-20 2.97E-19 42 197 "OSBPL8,ANK2,EIF4G3,USP6,CBFA2T2,QKI,HECTD1,NCOR1,HDAC4,DAPK1,IP6K1,FBXL5,PLPPR4,CPEB2,FAM78B,EGR3,AFF2,ZMAT1,AGFG1,LAMP2,MEIS1,MEIS2,NOVA1,EPB41L4B,LRRN3,PRKAB2,CNNM2,PBRM1,CHD9,CPEB4,SPART,LARP4,PLCB1,ANKRD28,TACC1,CAMTA1,SATB2,TCF12,R3HDM1,AMACR,ZIC1,SENP7" MicroRNA hsa-miR-1295:mirSVR_lowEffct hsa-miR-1295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-20 7.87E-17 3.29E-20 3.03E-19 49 270 "KLHL13,SMIM17,AMPD2,DPY19L3,SLC25A14,MS4A7,MYRIP,DCAF8,ARMCX2,RHOBTB1,CDON,DTNB,MAMLD1,ABCC5,EPHB1,DNAJC27,FCGR1B,CHL1,DISC1,LPAR4,STMN2,C1QL4,IL6ST,KCNN1,MEIS2,TCEAL5,NNAT,TBC1D25,STRN3,MASP1,QRICH1,PTPRN2,ACSS3,PBRM1,ROBO1,KIAA0895L,CCDC112,CSRNP3,FNDC3A,PPP4R3A,SEPHS1,MAST1,SMARCC2,PDZD2,ZSWIM8,SP4,DOCK9,MTMR14,ZNF213" MicroRNA hsa-miR-320a:Functional MTI Functional MTI miRTarbase 1.57E-20 8.79E-17 3.67E-20 3.38E-19 74 584 "ADD1,UNC5A,TBC1D14,AK2,MARCH4,SEMA7A,EP400,TNRC6C,ATP1A1,ARHGEF2,ABCG2,C2CD2,NCOR1,EARS2,POM121,MED12,DPYSL2,TMTC1,EIF4G1,USPL1,EPB41,TUBA1B,PRMT5,SYNCRIP,SRCAP,TNRC6A,GLUL,GPT2,ZNF496,RBPJ,TJAP1,KITLG,MYO6,OCRL,OPA1,PKM,POLR2F,WBP1L,ANKHD1,SALL1,SBF1,HES6,SEC14L1,HSPA4L,FAM102A,CPEB3,SLC6A8,ATF7IP,SMARCC2,ERC1,ARHGAP26,TSPYL2,NXT2,NSFL1C,ZC3H4,PRRC2C,TAL1,SATB2,USP22,ARL10,CBX5,TMPO,R3HDM1,CABIN1,SMUG1,PDSS1,TSC1,ZFP37,ZIC2,ZFAND5,SMARCAD1,INTS3,RNF103,RTN4" MicroRNA hsa-miR-502-3p:PITA hsa-miR-502-3p:PITA_TOP PITA 1.60E-20 8.97E-17 3.75E-20 3.45E-19 39 169 "ACTN1,KLHL13,OGT,CDC14B,BCL7A,JAZF1,PTBP2,DCLK1,ZMYM4,DLGAP2,FAM131B,KIAA0408,DGKB,NR1D2,CPEB2,DNAJB6,GRIA2,CIT,MGAT3,MYCN,NEFM,CLDN11,PCDH9,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,ZFHX4,SCN2B,PDZD2,PEG10,PRRC2C,ITGB3BP,DOK6,UBE2H,TMEM198,ADAMTS9,ST8SIA2,GAN" MicroRNA hsa-miR-575:PITA hsa-miR-575:PITA_TOP PITA 1.61E-20 9.01E-17 3.76E-20 3.46E-19 41 188 "PCDH19,CHRD,SLC4A4,CACNA2D1,PTBP2,LRBA,SLC35F1,SLITRK5,DBN1,SACS,DNM1L,PHC2,EIF5,EPHB1,FGF1,PRKAG2,GPD1,TMEM121B,PCLO,GRIA2,NEGR1,KCND1,KCND2,MAP2,PDE1C,PDE1B,LRRN3,RGS3,SCN2B,SCAF8,CHD9,FAM81A,ADAMTS17,FBXW11,PUM2,ZBTB38,CADM2,PCBP4,WNK3,HNRNPA3,ACTR3B" MicroRNA hsa-miR-1911:mirSVR_highEffct hsa-miR-1911:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-20 1.04E-16 4.33E-20 3.98E-19 51 294 "GALNT13,AP2A2,CC2D2A,ALCAM,UNC79,LCORL,SEC11C,CAST,METTL6,B4GALT6,CNR1,COL4A5,AKAP12,CYBB,HDAC9,ZNF804A,GSDME,RHOBTB1,PLPPR4,SV2B,RABEPK,NSRP1,DLC1,SMC2,HRASLS5,IQGAP2,GRIK4,MIER3,VSIG4,KCNN2,SYTL4,MEF2C,NUCB2,PPP2R5E,CARF,ATP8B4,LRRK2,SH3BGR,CHD9,CNKSR2,DZIP1,KDM3A,DBNDD2,TCF12,FRYL,THRA,RIMBP2,EMSY,KCNAB1,MPPE1,FZD3" MicroRNA hsa-miR-4753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-20 1.06E-16 4.41E-20 4.06E-19 53 317 "AS3MT,MTA3,TAOK1,CDC42BPA,PARG,USP37,GPR146,PROM1,CAMK2G,SPAG9,CD86,RIMS4,CST3,PITPNM3,ZSCAN23,GAPVD1,MAML1,ZC3H11A,RCAN1,RGS17,EMX2,NRN1,FGF1,CELF1,SULT1C4,PTPRT,NEGR1,IGF1,ZIC5,IL6R,GPR155,NOVA2,NPTX1,P2RX7,PDE3A,PLCL1,PPARA,KANSL1,PRKCB,PTPRN2,ZSCAN2,FIGN,TMLHE,CSRNP3,ATXN7,SGK1,RBM26,ANKRD28,EXOC7,TNS1,ZBTB38,ZNF195,CADM2" MicroRNA hsa-miR-18a-5p:TargetScan hsa-miR-18a-5p TargetScan 1.90E-20 1.06E-16 4.43E-20 4.07E-19 45 229 "KCTD16,ALCAM,DPP10,NCOA1,INSYN2B,FUBP1,CNR1,NRG2,CLIP3,DOCK4,LIN54,PLXNC1,ERBB2,CEP85L,FER,FGF1,CAMKK2,ATXN2L,HSF2,IGF1,KIT,MBNL1,PDE4D,PDE1B,GPSM2,PRKACB,MAPK4,DIRAS2,RBBP8,GTDC1,ROBO2,FAM192A,SATB1,CSRNP3,CCDC88A,CDK19,MESP1,NXT2,FRYL,DICER1,NACC2,CBX5,CADM2,FZD3,RNF146" MicroRNA hsa-miR-18b-5p:TargetScan hsa-miR-18b-5p TargetScan 1.90E-20 1.06E-16 4.43E-20 4.07E-19 45 229 "KCTD16,ALCAM,DPP10,NCOA1,INSYN2B,FUBP1,CNR1,NRG2,CLIP3,DOCK4,LIN54,PLXNC1,ERBB2,CEP85L,FER,FGF1,CAMKK2,ATXN2L,HSF2,IGF1,KIT,MBNL1,PDE4D,PDE1B,GPSM2,PRKACB,MAPK4,DIRAS2,RBBP8,GTDC1,ROBO2,FAM192A,SATB1,CSRNP3,CCDC88A,CDK19,MESP1,NXT2,FRYL,DICER1,NACC2,CBX5,CADM2,FZD3,RNF146" MicroRNA hsa-miR-331-3p:mirSVR_highEffct hsa-miR-331-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.92E-20 1.08E-16 4.48E-20 4.12E-19 50 283 "AS3MT,GALNT13,FAHD2CP,MTUS1,SPOP,SEMA7A,RGS9,NRP2,KALRN,CD38,ZMYM4,GPRASP1,GAPVD1,EARS2,TBC1D5,ELN,NRN1,RPS6KC1,SCML2,FCGR3A,BAIAP2,NELFCD,NBEA,OGA,GAD1,IP6K3,DISC1,NEU3,COQ10A,KIF5A,MEIS1,THYN1,MYO7A,ZC3H12B,PDE1C,GNG2,SMIM7,TUG1,STRC,RIC8B,RPE,ABCA11P,KIF16B,ANKRD6,TRERF1,C18orf54,TRIM9,FTSJ1,PRDM8,ADAMTSL3" MicroRNA hsa-miR-208b:mirSVR_highEffct hsa-miR-208b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.99E-20 1.11E-16 4.62E-20 4.26E-19 41 189 "FAM131A,TMEM108,BLM,SYNJ1,PRC1,CDO1,CHN2,QKI,MAP4K4,IQCK,ZNF804A,CPEB2,EDNRB,KCTD3,MED12L,ANKFY1,DISC1,CBX1,GRIA2,RNF165,HNMT,CELF5,TRHDE,PEX2,USP47,RIC8B,PNMA8A,ROBO2,FBXW7,TCP11L1,RYR3,CHD9,RCOR3,TTC17,ARHGEF9,SATB2,ZEB1,DOCK9,ERCC6L2,MICU3,PHTF2" MicroRNA hsa-miR-501-3p:PITA hsa-miR-501-3p:PITA_TOP PITA 2.01E-20 1.12E-16 4.67E-20 4.30E-19 39 170 "ACTN1,KLHL13,OGT,CDC14B,BCL7A,JAZF1,PTBP2,DCLK1,ZMYM4,DLGAP2,FAM131B,KIAA0408,DGKB,NR1D2,CPEB2,DNAJB6,GRIA2,CIT,MGAT3,MYCN,NEFM,CLDN11,PCDH9,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,ZFHX4,SCN2B,PDZD2,PEG10,PRRC2C,ITGB3BP,DOK6,UBE2H,TMEM198,ADAMTS9,ST8SIA2,GAN" MicroRNA hsa-miR-1265:PITA hsa-miR-1265:PITA_TOP PITA 2.01E-20 1.12E-16 4.67E-20 4.30E-19 39 170 "ASIC1,XKR4,NCOA1,NRG2,RIMS4,CNTNAP2,ELMSAN1,CPEB2,DPYSL2,EMX2,ADAMTS6,MIER3,ZIC5,ADAM11,SHC3,MYCN,NF1,NOVA1,PDE3A,GPR85,PMP22,PPP2R5E,KANSL1,CNNM2,SNX22,NCBP3,SH3GL3,CHD9,NLGN1,CPEB4,ERC1,CLASP2,LARP4,STXBP1,PLCB1,SYT1,WSCD1,FRYL,FLRT2" MicroRNA hsa-miR-142-3p:PITA hsa-miR-142-3p:PITA_TOP PITA 2.07E-20 1.16E-16 4.81E-20 4.43E-19 42 199 "FMNL2,TAOK1,APC,ARNTL,ZBTB10,ATP2A2,ARHGEF2,CFL2,SOCS6,HECTD1,RCHY1,SH2B1,PUM1,USP6NL,CPEB2,ACSL4,SUCO,AFF2,GHR,KAT7,BACH2,MAP2,AFF1,GPR137C,PDE4B,STRN3,SCAF8,SGK1,FNDC3A,WDR37,ATF7IP,SOX11,TEX2,SS18,STAU1,PLCB1,SYPL1,TBL1X,XPO1,SLC38A1,NAV3,PDSS2" MicroRNA hsa-miR-1236:PITA hsa-miR-1236:PITA_TOP PITA 2.08E-20 1.17E-16 4.85E-20 4.46E-19 46 240 "SPOP,CAMK2A,CAMK2G,CHN2,CLCN3,SH2B1,CRY2,FAM131B,POM121,DPH1,PDCD6IP,EBF1,PAN3,TAOK3,DLC1,SUCO,CHL1,PCDH17,KAT7,ADAMTS6,ATXN2L,ZIC5,KCNN3,PACRG,MAP2,NTRK3,ANKRD16,GRAMD1C,BCAS3,FAM184A,FBXW7,ZC3H14,NCBP3,CPEB3,FBXO11,EPN2,RCOR3,PDZRN3,ERC1,SS18,ARHGEF9,ANKRD28,TCF4,FAM155A,ZIC1,NAV3" MicroRNA hsa-miR-4533:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-20 1.28E-16 5.29E-20 4.87E-19 45 230 "HECW2,TAOK1,LTBP4,TRMT9B,CDC14B,DPY19L3,TTLL9,BCL7A,RUNX1T1,CBFA2T2,ZNF385A,CRY2,DCAF4,FAM131B,DBN1,PHC2,GCK,TNRC6A,PRRC2B,GSN,TNFAIP8L3,ZFYVE27,NOVA2,PKM,ZNF426,IQSEC3,PRRT2,SETD5,SGK1,SHMT2,AMBRA1,R3HDM2,PEX26,IQSEC2,CDK19,SS18,MPRIP,TMEM9,ASXL3,WBP2,TUBB2A,WRN,ZNF708,CIAPIN1,ITM2C" MicroRNA hsa-miR-518e:mirSVR_lowEffct hsa-miR-518e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.38E-20 1.33E-16 5.52E-20 5.08E-19 60 403 "DGCR6,NCKAP5,NDRG3,PSMG3-AS1,ADCY5,BRAP,RNF150,ZNF578,PHYHD1,PPFIA3,LINC00173,BACH1,THSD7A,MAP4K4,MYRIP,ZNF385A,ABCG1,SOCS5,EARS2,SPOCK2,SPATA2,USP3,CELSR3,EPHB1,SLC9B2,FLNC,TUBA8,GGTA1P,ZNF276,TNRC6A,ZNF638,PCLO,ATXN2L,AGFG1,RTL5,ZC3H12B,NEFH,NME4,PFKFB4,CCSER2,PLIN1,ING3,POU6F1,MTMR10,SH3TC2,RBBP8,CCDC25,CPEB4,RBM34,MGRN1,TTTY15,TUBB1,P2RY12,LGI4,PARP11,PDSS2,DOCK8,KAT6A,TTC7A,FRMD6" MicroRNA hsa-miR-1272:PITA hsa-miR-1272:PITA_TOP PITA 2.43E-20 1.36E-16 5.64E-20 5.19E-19 44 220 "RALGAPA1,SLC24A4,APAF1,ARNTL,JAZF1,MAGI1,CCPG1,FOXN3,CNR1,AKAP6,DGKB,SLC12A6,KCTD3,HPCAL4,AFF2,TNRC6A,PCLO,ADAMTS6,NCKAP1L,NEGR1,SMAP1,STXBP5,MXI1,NOVA1,STRN3,PTPRD,OXR1,PBRM1,AP1AR,TNFRSF19,AMBRA1,CHD9,CCDC88A,SP4,PEG10,CLASP2,ST5,RHBDL3,TCF4,RIMBP2,PRDM10,WNK3,RTN4,FRMD6" MicroRNA hsa-miR-18b:PITA hsa-miR-18b:PITA_TOP PITA 2.44E-20 1.37E-16 5.67E-20 5.22E-19 41 190 "ALCAM,DPP10,NCOA1,SYNGR3,CCPG1,FOXN3,TBPL1,CLOCK,CLIP3,SOCS5,RIMS2,DOCK4,ALKBH8,SLC12A6,SUCO,OGA,ATXN2L,HLF,HSF2,SOWAHA,IGF1,KIT,MBNL1,MEF2C,PDE4D,PDE1B,GNG2,POU6F1,SNRK,RBBP8,CSRNP3,CCDC88A,FNBP1,TEX2,CDK19,CLASP2,NXT2,TRIM2,FRYL,DICER1,CADM2" MicroRNA hsa-miR-18a:PITA hsa-miR-18a:PITA_TOP PITA 2.44E-20 1.37E-16 5.67E-20 5.22E-19 41 190 "ALCAM,DPP10,NCOA1,SYNGR3,CCPG1,FOXN3,TBPL1,CLOCK,CLIP3,SOCS5,RIMS2,DOCK4,ALKBH8,SLC12A6,SUCO,OGA,ATXN2L,HLF,HSF2,SOWAHA,IGF1,KIT,MBNL1,MEF2C,PDE4D,PDE1B,GNG2,POU6F1,SNRK,RBBP8,CSRNP3,CCDC88A,FNBP1,TEX2,CDK19,CLASP2,NXT2,TRIM2,FRYL,DICER1,CADM2" MicroRNA hsa-miR-302c-3p:Functional MTI Functional MTI miRTarbase 2.53E-20 1.42E-16 5.88E-20 5.41E-19 68 507 "RNF157,FZD9,SORCS2,OSBPL8,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,CAMK2A,PRC1,ZBED1,DIS3L,CLCN3,IGDCC3,ZNF385A,ENTPD4,SOCS5,UBXN2A,GREB1,DNAL1,NR1D2,SLC12A6,DPYSL2,FEM1B,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,MSANTD4,TRAF3IP2,KIAA1841,SRCAP,MALT1,CRCP,GRB10,HAS2,IL6ST,KCNB1,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,LRP12,PRKACB,RAD51D,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-6788-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-20 1.51E-16 6.26E-20 5.76E-19 69 521 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,SYNJ2,ISPD,SLC16A4,EPS15L1,SUMF2,UBXN2A,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,PLEKHA1,MRNIP,MTSS1L,IGSF6,ANKFY1,TRAF3IP2,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,SDK2,RETREG2,PPARA,MTMR10,PTPRE,CEP97,SETD5,KLHDC8A,MYO18A,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RPRM,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5" MicroRNA hsa-miR-223:PITA hsa-miR-223:PITA_TOP PITA 2.73E-20 1.53E-16 6.33E-20 5.83E-19 45 231 "PKP4,APC,ZBTB10,NCOA1,MTMR2,PTBP2,QKI,SLC35F1,SLITRK5,ELMSAN1,KLHL3,SACS,MBNL2,OLFM1,FOXO3,CSPG5,GABRB3,SPIN1,HLF,RBPJ,IL6ST,INPP5B,LMO2,MEF2C,NDP,NEFH,PDE4D,ANKRD16,LRP12,RANBP3L,WBP1L,TMEM255A,FBXW7,ATXN2,SCAF8,SLC8A1,SOX11,ERC1,NFASC,SYT1,CAMTA1,TCF4,DOCK9,REEP1,FAM13C" MicroRNA hsa-miR-629:PITA hsa-miR-629:PITA_TOP PITA 2.74E-20 1.53E-16 6.35E-20 5.85E-19 37 153 "FZD9,KLHL13,OSBPL8,SEMA6A,CADPS,LETMD1,CS,AIF1L,KIAA0753,CPEB2,EIF1,AMOTL2,UBE2E3,AGAP3,GABRB3,C15orf41,PCDH17,CSDC2,RNPS1,SPIN1,PCLO,GRIN2D,KAT7,SMAP1,IGF1,MAPK10,FAM102A,BTBD3,WDR47,SOX11,HECW1,CLSTN2,ELOVL4,TCF4,WBP2,LAMP5,FZD3" MicroRNA hsa-miR-6873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-20 1.60E-16 6.60E-20 6.08E-19 59 392 "AS3MT,MTA3,SORCS2,SPOP,PTCH2,ATP1A3,PROM1,CABP7,CD86,RIMS4,CST3,PLXNA4,PITPNM3,GAPVD1,RCAN1,EMX2,NRN1,GABRG2,GALC,GATM,PCDH17,PARD3B,FRMD3,LSAMP,NFIX,PALM,PDE3A,PLCL1,KANSL1,SNRK,SH3TC2,RDX,ATXN7,SCN2B,ZFP30,CPEB3,CHD9,SLC6A8,ZFP1,ZNF667,LIMCH1,ZNF415,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,MGRN1,BHLHB9,TNS1,TSC1,UBE2H,ZNF23,CADM2,PRDM10,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-567:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-20 1.68E-16 6.95E-20 6.40E-19 41 191 "TMEM132B,HACE1,SORCS2,TAOK1,CFL2,IGLON5,MYADM,DCAF8,SV2B,DMD,MBNL2,CERCAM,KATNAL1,UBE2E3,JKAMP,GABRG1,GATM,SESN1,MMADHC,CBX1,BVES,ZDHHC15,IGF1,KCNQ3,MKLN1,MYO5A,NELL2,SDK2,OXR1,RIC8B,PGBD4,SATB1,CSRNP3,PEX26,PEG10,NECAB1,ARHGEF9,PLCB1,CSMD1,KCNK12,ADAMTS9" MicroRNA hsa-miR-100:mirSVR_lowEffct hsa-miR-100:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.08E-20 1.72E-16 7.13E-20 6.56E-19 42 201 "TAOK1,ZFAT,ARNTL,SYNJ1,SCAPER,MTMR3,MTMR2,LURAP1,KALRN,HINFP,UBXN2A,HDAC4,DBI,PLPPR4,PHF20L1,IRAK4,NOP56,MEGF10,ALDH1L1,ADAM28,HNF4G,C2orf72,INSM1,LSS,MYO7A,PURG,ING3,EPDR1,PTPRN2,FBXO11,SLC14A1,BTBD7,MYO16,KDM4C,TSPYL2,ST5,ANKRD28,SYNE1,TMPO,VLDLR,GAL3ST3,URM1" MicroRNA hsa-miR-454*:mirSVR_highEffct hsa-miR-454*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-20 1.79E-16 7.38E-20 6.80E-19 52 309 "RTL9,TAOK1,FGD2,NUMB,DPY19L3,LURAP1,CABP7,SRSF11,MAP4K4,MYRIP,GREB1,DOCK4,GPRASP1,RIPOR2,HDAC4,DDX46,RHOBTB1,CHRDL1,ARRDC4,EDN1,EPB41L2,RAB9B,ATP2C1,FAM120B,GDF9,CBX1,DIDO1,PLCD4,HSF2,NME9,POC1B,MSR1,MXI1,NF1,GPR137C,RETREG1,PPM1B,STK32A,C1orf109,TMEM255A,ZNF331,CXXC4,TMCC1,SP4,SPTAN1,ATP10B,SYNE2,PUM2,GPRIN3,TMPO,PIK3R5,ATP6V0E2" MicroRNA hsa-miR-3193:mirSVR_lowEffct hsa-miR-3193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.24E-20 1.81E-16 7.48E-20 6.89E-19 59 393 "RALGAPA1,NCKAP5,C1QTNF3,NCOA1,NRP2,METTL6,P2RX6,CD38,ZBED1,CPNE6,SUMF2,AHCTF1,ZNF521,SLC35F1,RASGEF1C,PLCXD3,CTH,FAM131B,RIPOR2,HDAC4,CD99L2,SLC29A4,DTNA,PHF20L1,APH1A,SRRM1,FCGR1A,NELFCD,TUBA8,GGT7,MSL3,GPR12,GAREM2,KNDC1,IPO5,MYO7A,NINJ2,NME4,PPP1R1A,PPP2R2C,NDUFS7,SNRK,NKAIN1,FAM66C,ROGDI,RASGRF2,RNASE1,EPHA10,MEG3,SARS,ANKRD6,NMNAT2,NFASC,BHLHB9,ZIC1,NDRG4,ZNF138,FAM219B,RNF170" MicroRNA hsa-miR-6838-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.32E-20 1.86E-16 7.68E-20 7.07E-19 62 431 "AXIN2,FZD9,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,CA8,RUNX1T1,CCNT1,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,RASSF2,YTHDC1,DMPK,DMTF1,FCF1,HEYL,PLEKHA1,ZNF391,ANKMY1,ZNF585B,MSANTD4,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,CHIC1,MYO5A,OCRL,PDE4D,PIK3R1,PSAT1,PTPRD,RBBP6,ZFHX4,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,ZMAT3,TPM2,TUBB2A,UBE2H,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-369-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-20 1.89E-16 7.79E-20 7.17E-19 38 163 "ABCF1,XKR4,ADD2,CDC14B,STX16,NRP2,CA8,ABCG2,QKI,BAG4,PITPNC1,TMTC1,MBNL2,ACSL4,ZBED3,TNRC6A,LUZP2,BACH2,MIER3,LSAMP,OCRL,PKM,EPDR1,MAPK7,ZFHX4,BTBD3,ZNF621,SYP,TACC1,TRIM2,SIK3,ZMAT3,TRPS1,TUBB2A,UBE3A,TBC1D15,SPIRE1,SLC38A1" MicroRNA hsa-miR-492:mirSVR_highEffct hsa-miR-492:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.42E-20 1.92E-16 7.90E-20 7.28E-19 51 298 "RALGAPA1,ADORA2A,KCTD16,MYH7B,KCNAB2,ATP6V1G2,KALRN,CD38,DGKI,NDST3,HINFP,CCDC144A,RIPOR2,ARMCX4,ZC3H11A,MAMLD1,C8orf37,DISC1,USP19,DCLK2,GNAL,LPAR4,KCNB1,MAT2A,MATN3,ADAM11,PPM1L,LAYN,SMIM11A,IGSF11,SH3KBP1,PIGG,TMEM260,SLC25A48,YY1AP1,SPIN3,ATP8B4,CSRNP3,SUPT20H,TRA2B,SP4,NEK4,TMEM150C,SYN2,AP4E1,SLC44A1,TNS1,VSNL1,TFIP11,RNF103,FIP1L1" MicroRNA hsa-let-7d-5p:Functional MTI Functional MTI miRTarbase 3.68E-20 2.06E-16 8.48E-20 7.81E-19 59 394 "FZD9,MTUS1,ZNF578,FAM135A,AQP6,IGDCC4,NCOA1,BACH1,CRY2,DNAL1,SPATA2,ZBTB24,MTX3,DNAH9,ARRDC4,GOLT1B,E2F6,EDN1,ANKRD46,EIF4G2,KATNAL1,DLC1,TRMO,PDLIM5,CELF1,DISC1,GATM,TNRC6A,POLL,FUT10,RABL2A,IL6R,KPNA5,PAXBP1,THYN1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,ERC1,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,DICER1,CBX5,TST,TUBB2A,SLC35A4,ZNF28,SMARCAD1" MicroRNA hsa-miR-516a-3p:PITA hsa-miR-516a-3p:PITA_TOP PITA 3.69E-20 2.07E-16 8.52E-20 7.84E-19 43 212 "ASIC1,LDLRAD4,CACNB4,CCPG1,RIMS2,TM9SF4,DPP6,MBNL2,DCTN4,ETV1,MEX3B,PCDH17,PCLO,HLF,KCNN3,MEF2C,NEXMIF,MYT1,RASGEF1B,PTPRN2,GTDC1,S100B,SCP2,TET1,PEG10,SPTB,PLCB1,SYT1,TCF4,SATB2,ZEB1,TCF12,CLASP1,SLC44A1,NR2E1,TMEM237,ZNF189,ADAMTS9,NAV3,RGS7BP,KAT6A,ADAMTS10,SOCS4" MicroRNA hsa-miR-6825-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.86E-20 2.16E-16 8.90E-20 8.19E-19 58 382 "RNF157,ADD2,CASKIN1,SORCS2,LTBP4,PRX,ARRB1,CAMK2A,CBS,METTL6,EVI5L,CRMP1,CRY2,RGS6,SLITRK5,ABCC5,EIF4G1,ING4,CELF1,BRSK1,SRCAP,PRRC2B,SHISA6,SOWAHA,KCND1,KCNH2,KCNK3,MSI1,NBL1,NFIX,SLC11A2,OGG1,PDE4A,GPR173,PPP2R2B,KANSL1,BDNF-AS,PRRT2,C12orf49,RPS6KA2,EMID1,PKNOX2,FNBP1,NFASC,CLSTN2,CAMTA2,SSTR1,USP22,SLC19A3,THRA,NACC2,CBX5,UBTF,MGAT5B,KLC2,RICTOR,URM1,HNRNPA3" MicroRNA hsa-miR-211-5p:Functional MTI Functional MTI miRTarbase 4.04E-20 2.26E-16 9.32E-20 8.58E-19 54 334 "AS3MT,XKR4,ADCY5,MTA3,SORCS2,AK2,SPOP,SEMA4G,ARSE,ASGR1,BCL7A,BID,MYRF,LURAP1,CAMK2G,SEC31B,PLCXD3,ELMSAN1,CHRDL1,FEM1B,SLC43A2,AMOTL2,ANKFY1,SRCAP,TPPP,PTPRT,PADI2,BACH2,MIER3,EID2B,LSAMP,MBNL1,XRRA1,SAMD5,MX1,NPTX1,PDE3A,KANSL1,MARCH1,CEP97,DPF2,GTDC1,RORB,ELP2,ATXN7,GALNT10,MYO18A,ZBTB43,IQCE,SATB2,TCF12,ZDHHC20,DPF3,GAN" MicroRNA hsa-miR-3650:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-20 2.47E-16 1.02E-19 9.37E-19 37 155 "XKR4,PTCHD1,CARNS1,MARCH4,BCAS1,CCNT1,TMEM184B,IGLON5,AKAP5,SLC35F1,PYGO1,DCAF8,DBT,TMEM130,PLEKHA1,COQ7,ATP13A4,ZBED3,HHIPL1,GLI2,AP4S1,MAP2,PPM1L,MYO5A,PRKCB,MAPK10,SLC25A36,PGBD4,SGK1,SLC2A5,KIF13A,LHPP,ZC3H4,FAM208A,NR2E1,KCNK12,ZDHHC20" MicroRNA "AGGGCAG,MIR-18A:MSigDB" "AGGGCAG,MIR-18A:MSigDB" MSigDB 4.80E-20 2.69E-16 1.11E-19 1.02E-18 34 129 "OGT,SEMA4G,STOML1,QKI,PHC2,MBNL2,PAN3,DLC1,STRADA,CPLX2,TTBK1,CRCP,CIT,ZFYVE27,MAPT,MAT2A,ZC3H12B,PFKFB4,PSD,PBRM1,SMPD3,MAPKBP1,TACC1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LRRC8A,HIRA,EIF4ENIF1,ST8SIA2" MicroRNA hsa-miR-4739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-20 3.21E-16 1.32E-19 1.21E-18 50 290 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,ZNF496,SLC6A17,MAT2A,NBL1,NFIX,TBC1D25,RETREG2,POLR2F,SH3TC2,MORC4,HES6,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,THRA,NACC2,PPIL6,TUBB2A,BCL2L13,TSPAN11,ZNF70,PARP11,TMEM63C,FAM198A" MicroRNA hsa-miR-514:PITA hsa-miR-514:PITA_TOP PITA 6.04E-20 3.38E-16 1.39E-19 1.28E-18 39 175 "C6orf89,NCOA1,TAOK2,NRXN3,MYRIP,ERC2,NR1D2,FSD1L,EIF1,TAOK3,PRKAG2,SUCO,SYNCRIP,TNRC6A,LPAR4,TPPP,GRIA2,KCNB1,NCOA7,NEXMIF,TMEM260,PTPRG,RFX3,BAALC,ZC3H14,RTN1,FNDC3A,SULF2,ARHGEF9,TCF4,TRIM2,TCF12,PCDHB6,AMACR,EIF4ENIF1,ZIC1,NAV3,HNRNPA3,NETO2" MicroRNA hsa-miR-1294:PITA hsa-miR-1294:PITA_TOP PITA 6.04E-20 3.38E-16 1.39E-19 1.28E-18 39 175 "ADRB2,PITPNM2,SEMA4G,CFL2,ARMC8,ZNF385A,RGS6,SEC24C,SPOCK3,DMD,EDN1,EGR3,STARD3NL,EIF1,TMEM121B,CNTRL,LINGO1,ADAMTS6,HAS2,DDX19B,MAT2A,CHIC1,GIT1,MXI1,NEFM,PDE4D,PTPRD,KHDRBS2,MSANTD2,RDX,KCTD17,SEC14L1,ARX,AMBRA1,SULF2,ANKRD28,SATB2,TRIM2,TBC1D15" MicroRNA hsa-miR-873:PITA hsa-miR-873:PITA_TOP PITA 6.10E-20 3.42E-16 1.40E-19 1.29E-18 44 225 "ZNF608,RTL9,FAM135A,MAP4K3,MARK4,BCL7A,BMP7,CACNA1I,NOG,FOXN3,TM9SF4,MATR3,MYEF2,DMD,YAF2,EGR3,RGS17,PAN3,MEX3B,OGA,ARFIP1,AHDC1,PADI2,ATXN2L,HNRNPM,PCSK5,TMOD2,ZNF655,DPF2,PBRM1,ZNF532,KCNIP3,POGZ,LARP4,ELOVL4,KANK1,SULF2,SYN1,SYN2,PJA1,CAMTA1,SMG6,USP1,ZIC2" MicroRNA hsa-miR-4722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.78E-20 3.80E-16 1.56E-19 1.44E-18 64 463 "AS3MT,RNF157,ADD1,ESYT2,SORCS2,ABCD2,CDC14B,ARSE,SLC4A4,ALDH7A1,LDLRAD4,QKI,CREM,RNF14,HINFP,CSNK1E,KIAA0408,DNAL1,EXOG,CD99L2,CNNM1,MRNIP,RGS17,EMX2,SLC43A2,FKTN,FDFT1,VTI1B,FOXO3,PDLIM5,CRCP,RNF165,ZDHHC15,EID2B,IL6R,KCNQ3,NCOA7,LSAMP,MAN2A2,ALDH1L2,NOVA2,MTRF1L,APTX,TMEM231,ZNF844,GTDC1,PGBD4,RXRA,SCN2B,ZFP30,PEX26,ZNF667,ARHGAP26,AGTPBP1,SIN3B,ZNF106,GALNT17,ARL10,ERCC6L2,RPL7L1,CFAP298,AGMO,ZNF70,MPPE1" MicroRNA hsa-miR-146b-3p:mirSVR_highEffct hsa-miR-146b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.60E-20 4.25E-16 1.74E-19 1.61E-18 64 464 "NCKAP5,PTCHD1,DYNLL1,STX16,TTLL9,MTMR2,KALRN,CAMK2G,ISPD,PLEKHB1,CPS1,SNCAIP,GSDME,DYNC1I1,DNM1L,YAF2,SUGP2,TUBD1,GORAB,ATP13A4,JKAMP,GABRG2,GALC,GPR12,AP4S1,SCIN,IL6ST,MAT2A,AQP11,MBNL1,LRP1B,MEF2C,AFDN,MMP16,NF1,NRCAM,NUCB2,IGSF11,CYTL1,TMIE,PPP1R1A,TMEM260,ZSCAN2,CEP97,OXR1,RGS4,CARF,GSTCD,LRFN5,TNFRSF19,COPZ1,PPP4R3A,CPEB4,SEPT8,ADHFE1,PLCB1,ADGRL3,HIF3A,SLC44A1,RUNDC3B,OSBP2,WRN,SMARCAD1,UPF3A" MicroRNA hsa-miR-555:mirSVR_highEffct hsa-miR-555:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.65E-20 4.28E-16 1.76E-19 1.62E-18 63 451 "KCNH8,CLK4,UNC5A,MTUS1,HECW2,CARNS1,PHF12,TMEM108,BACH1,BCHE,CALB2,PTBP2,CCPG1,CHN2,MAP4K4,NCOR2,ARHGAP24,DCAF8,ZC3H11A,GRIN3A,RASGRP1,TENM1,PAN3,CEP78,FGF11,IP6K2,ATP13A4,DISC1,TXNL4A,GPD2,GRM2,IDH3B,RBPJ,KCND2,CREG2,IPO5,NCOA7,MAP2,SAMD14,NELL2,NTRK2,CHAMP1,NALCN,CCSER2,PLTP,FA2H,RASGEF1B,CNNM2,RET,ERI2,RGS3,EXD2,GSTCD,CSRNP3,ZC3H13,ADHFE1,SATB2,GPRIN3,FRYL,TP53BP2,TPM1,TRIM9,FIP1L1" MicroRNA hsa-miR-3144-5p:mirSVR_highEffct hsa-miR-3144-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.69E-20 4.30E-16 1.77E-19 1.63E-18 52 315 "SYS1,LRCH2,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,BCAS1,CAMK2G,ARHGEF25,CBR1,CBS,CERS5,MAGI1,SH2B1,SEC24C,DCAF8,DCTN1,C2CD2L,EPHB1,ZNF589,FGF11,STAU2,GABBR1,DISC1,SESN1,AIFM3,FAM95B1,INSM1,BLOC1S2,NRBP2,MYCN,LAYN,NPR2,PDPK1,GNG2,MAPKAP1,SEPT4,DEF8,RGS12,SH3GL3,CNKSR2,SLC6A8,ARHGEF40,PEG10,CDK19,LMO3,STAU1,TTBK2,CLASP1,TPM1,AMACR,TTC3,VAV1" MicroRNA hsa-miR-30c-1-3p:Functional MTI Functional MTI miRTarbase 7.72E-20 4.32E-16 1.77E-19 1.63E-18 69 531 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,SYNJ2,ISPD,SLC16A4,EPS15L1,SUMF2,UBXN2A,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,PLEKHA1,MRNIP,MTSS1L,IGSF6,ANKFY1,TRAF3IP2,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,SDK2,RETREG2,PPARA,MTMR10,PTPRE,CEP97,SETD5,KLHDC8A,MYO18A,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,FTSJ1,TFIP11,EVI5" MicroRNA hsa-miR-6727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-20 4.76E-16 1.95E-19 1.79E-18 64 465 "AS3MT,RNF157,ADD1,ESYT2,SORCS2,ABCD2,CDC14B,ARSE,SLC4A4,ALDH7A1,LDLRAD4,QKI,CREM,RNF14,HINFP,CSNK1E,KIAA0408,DNAL1,EXOG,CD99L2,CNNM1,MRNIP,RGS17,EMX2,SLC43A2,FKTN,FDFT1,VTI1B,FOXO3,PDLIM5,CRCP,RNF165,ZDHHC15,EID2B,IL6R,KCNQ3,NCOA7,LSAMP,MAN2A2,ALDH1L2,NOVA2,MTRF1L,APTX,TMEM231,ZNF844,GTDC1,PGBD4,RXRA,SCN2B,ZFP30,PEX26,ZNF667,ARHGAP26,AGTPBP1,SIN3B,ZNF106,GALNT17,ARL10,ERCC6L2,RPL7L1,CFAP298,AGMO,ZNF70,MPPE1" MicroRNA "GGCAGCT,MIR-22:MSigDB" "GGCAGCT,MIR-22:MSigDB" MSigDB 1.14E-19 6.35E-16 2.60E-19 2.40E-18 43 218 "EMILIN3,ADRA1B,PDZD4,BIN1,DPP10,USP37,ARRB1,WASF1,CABP7,KALRN,DGKI,FOXN3,CSF1R,RIMS4,HDAC4,IP6K1,SNAP91,PHF20L1,EMX2,FAM49B,MTHFD2,AGBL5,SMAP1,MAT2A,MBP,ADAM11,NFYA,NTRK2,PPARA,SNRK,DPF2,RIC8B,FBXW7,CHD9,DHX30,SEPHS1,SLC9A5,EPC1,KDM3A,SATB2,SIRT1,CLDND1,MAP3K12" MicroRNA hsa-miR-874:mirSVR_highEffct hsa-miR-874:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.32E-19 7.39E-16 3.03E-19 2.79E-18 60 417 "NCKAP5,GALNT13,ADD2,KIAA1324,TXNDC16,CARNS1,PHF12,ARNTL,INSYN2B,DYNLL1,N4BP2L1,BARD1,MTMR2,KALRN,SPAG9,LDB2,PLEKHB1,AKAP7,CPS1,HAPLN1,CNTNAP2,RHOBTB1,GRIN3A,DTNB,C3orf18,TUBD1,GORAB,SPECC1,MEGF11,LPAR4,AP4S1,IGFBPL1,MAT2A,MXI1,NRCAM,NUCB2,ZNF655,EXOSC10,PIGG,ZSCAN2,OXR1,RGS4,GSTCD,RORB,ABCA11P,COPZ1,ZFP30,PPP4R3A,CPEB4,ADGRL3,SATB2,HIF3A,THRA,ELP5,TRIM9,PRDM8,DOCK8,RSPRY1,MSRB3,DPF3" MicroRNA hsa-miR-1275:PITA hsa-miR-1275:PITA_TOP PITA 1.38E-19 7.72E-16 3.16E-19 2.91E-18 34 133 "KCNH8,NDRG3,HECW2,PCDH19,SEMA4G,ARNTL,NCOA1,JAZF1,CACNA1A,CACNA2D2,NRXN3,SH2B1,SLC12A6,DPP6,DUSP9,PHC2,AGAP2,DCTN2,ATXN2L,IGF1,GIT1,NFIX,PDE1B,SETD5,PKNOX2,SLC11A1,CPEB4,SMARCC2,ANKRD28,MTCL1,RIMBP2,TRPS1,SMARCAD1,URM1" MicroRNA hsa-miR-548d-3p:Functional MTI Functional MTI miRTarbase 1.42E-19 7.95E-16 3.25E-19 2.99E-18 50 296 "TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,MTMR3,FAM169A,PITPNC1,EDIL3,HIPK3,YAF2,CELSR3,MRO,ERBB2,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,THYN1,MYO6,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,NWD1,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,ATF7IP,FAM126B,FAM208A,ALG1,CLASP1,ARL10,TP53BP2,MKRN3,GAL3ST3" MicroRNA hsa-miR-361-3p:PITA hsa-miR-361-3p:PITA_TOP PITA 1.47E-19 8.22E-16 3.36E-19 3.09E-18 36 151 "AP2A1,PDZD4,OGT,FAM131A,ATP1A3,CACNA2D2,TAOK2,CNTFR,CDC42BPB,SH2B1,FAM131B,ZC3H11A,SV2B,EIF4G1,ELN,RASGRP2,AGAP3,SYT3,DCTN2,CPLX2,BACH2,PACRG,ADAM11,PPP3CA,USP47,PRRT2,PBRM1,FAM219A,ZSWIM8,TSPYL2,SZT2,THRA,RELL2,XPO1,TRIM9,SLC30A3" MicroRNA hsa-miR-6516-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-19 8.27E-16 3.38E-19 3.11E-18 77 650 "ABCF1,NDRG3,SLC24A4,HECW2,HACE1,ZNF578,SEMA6A,AQP6,CDC14B,ASPA,DOCK11,BACH1,BCL7A,PTBP2,CBS,CBFA2T2,CDR1,CCPG1,NRXN3,PLAA,TPP1,CPS1,CSNK1G3,PLCXD3,MYADM,GAPVD1,TMEM170A,DNAL1,PITPNC1,GUCD1,MTX3,DNAH9,MRO,RASA4,MRNIP,SLC43A2,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,TRMO,DISC1,CRCP,GLUL,GNG4,LILRA2,RNF165,MIER3,IGF1,IBA57,MXI1,CCSER2,TATDN3,NCR3LG1,MTMR10,CEP97,ZNF793,RBBP8,ALG9,PTGR2,NCBP3,FNIP1,SHC4,ATF7IP,FNBP1,LHPP,USP22,BHLHB9,PPIL6,SSBP2,USP1,LAT2,EVI5,GAN" MicroRNA hsa-miR-203a-3p:Functional MTI Functional MTI miRTarbase 1.51E-19 8.46E-16 3.46E-19 3.18E-18 51 308 "FMNL2,CASK,MARCH3,ASPA,BCL7A,FOXN3,SOCS6,HECTD1,CLOCK,UBXN2A,KIAA0408,FBXL5,DNAJB6,EDNRA,SEMA3D,MRO,RGS17,NCALD,VPS26C,DLC1,POLR1B,ZBED3,CIT,KIF2A,LIFR,LOH12CR2,SMAD9,MBNL1,NFYA,PAX6,PSAT1,PRKACB,MAPK9,FBXW7,PEAR1,CPEB4,CXXC4,KIF13A,FAM208A,TBCEL,TCF4,SATB2,ZEB1,SLC44A1,NR2C2,TRPS1,ZNF24,DHX33,CADM2,NETO2,SPATA13" MicroRNA hsa-miR-331-3p:PITA hsa-miR-331-3p:PITA_TOP PITA 1.60E-19 8.93E-16 3.65E-19 3.36E-18 33 125 "XKR4,UNC5A,TRMT9B,SEMA4G,TAOK2,MYRIP,RIMS4,ELMSAN1,PHC2,EGR3,ELN,NRN1,PTK2B,SCML2,NBEA,TNRC6A,PLPP7,ATOH8,CAMK2N2,MEIS1,MEIS2,MSI1,CLDN11,PTPRD,C1orf109,RIC8B,FAM214B,PKNOX2,FAM126B,STAC2,ADGRL3,POLR3H,PRDM8" MicroRNA hsa-miR-149:PITA hsa-miR-149:PITA_TOP PITA 1.61E-19 8.98E-16 3.67E-19 3.38E-18 38 170 "PCDH19,SPOP,SEMA4G,SLC4A4,ADGRB2,SOCS6,B4GALT6,NCOR1,SNCAIP,SEC24C,RIMS4,CNTNAP2,LONRF1,KLHL3,EDNRA,CNNM1,EIF5,TENM1,OLFM1,FOXO3,AFF2,KAT7,FAM222A,CHIC1,MITF,GIT1,MSI1,NFIX,NNAT,SLC11A2,TNFRSF19,BTBD3,PHLDB1,TCF12,VLDLR,POLR3H,PDSS2,MSRB3" MicroRNA hsa-miR-4756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-19 9.88E-16 4.03E-19 3.71E-18 49 286 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,ZNF496,SLC6A17,MAT2A,NBL1,NFIX,TBC1D25,RETREG2,POLR2F,SH3TC2,MORC4,HES6,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,THRA,NACC2,PPIL6,TUBB2A,BCL2L13,TSPAN11,ZNF70,PARP11,FAM198A" MicroRNA hsa-miR-409-3p:TargetScan hsa-miR-409-3p TargetScan 1.78E-19 9.96E-16 4.07E-19 3.74E-18 44 231 "CLK4,KIAA1211,KCTD16,C1QTNF1,FAM135A,NRP2,CALM1,MTMR7,CFL2,LHX2,FHL5,PYGO1,MATR3,DPP6,EGR3,PLXNC1,ETV1,MED12L,IQCG,ANKFY1,PCDH17,GHR,GNAL,LNX1,BACH2,LIMS1,MAPT,NFIX,GPR85,GPSM2,FAM216A,SCHIP1,KANSL1,CEP41,PTPRG,RDX,DPF2,RORB,BTBD7,NECAB1,MFF,MSRB3,FXR1,CPNE4" MicroRNA hsa-miR-219-2-3p:PITA hsa-miR-219-2-3p:PITA_TOP PITA 1.81E-19 1.01E-15 4.13E-19 3.80E-18 40 190 "CCDC85A,HACE1,PTBP2,CAMK2G,MAGI1,CHN2,OSBPL3,APPL1,DOCK4,DBT,MTX3,GPHN,ANKFY1,PSD2,NBEA,FUT9,TVP23A,NTNG2,MIER3,IGF1,MEIS2,AFF1,MXI1,MYO5A,TMEM260,USP47,KHDRBS2,SCN8A,FNDC3A,NLGN1,BTBD3,SEPHS1,SLC12A2,SNAP25,SSTR2,ARHGEF9,SYT1,TCF4,RPGRIP1L,UGT8" MicroRNA hsa-miR-3662:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-19 1.07E-15 4.37E-19 4.03E-18 46 253 "FZD9,ZNF578,CDC25B,SRSF11,TOGARAM2,SPATA2,MRVI1,ACSL4,MED12L,UBE2E3,SEMA4D,CELF1,MSANTD4,MMADHC,RNPS1,TNRC6A,ZNF181,ZIC5,STMN1,ZNF680,MYO5A,GPR137C,CCSER2,PSAT1,EPB41L4B,SH3TC2,RFX3,KLHL11,CLIP1,SEMA6D,SGK1,BTBD3,SLC6A8,TMCC1,SOX11,ITPRID2,SLC35G2,ZMAT3,NACC2,UGT8,MFF,JMJD1C,ZDHHC20,FXR1,NETO2,GAN" MicroRNA hsa-miR-1197:TargetScan hsa-miR-1197 TargetScan 1.99E-19 1.12E-15 4.54E-19 4.18E-18 38 171 "PTCHD1,AK2,MADD,PDE8B,CCAR2,ATP1B3,ATP2B2,CACNA1A,CBFA2T2,CREM,PLCXD3,MTX3,HS3ST2,FARSB,EIF5,PCYOX1,CAMKK2,CELF1,GHDC,PPARGC1A,LYVE1,PAXBP1,MAT2A,MBD1,MMP16,DBNL,MYO6,NFIX,PAX6,FAM216A,MAPK10,GTDC1,CYB561D1,KIAA0895L,CCDC88A,BTBD7,NMNAT2,FTSJ1" MicroRNA hsa-miR-1321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-19 1.15E-15 4.68E-19 4.31E-18 49 287 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,ZNF496,SLC6A17,MAT2A,NBL1,NFIX,TBC1D25,RETREG2,POLR2F,SH3TC2,MORC4,HES6,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,THRA,NACC2,PPIL6,TUBB2A,BCL2L13,TSPAN11,ZNF70,PARP11,FAM198A" MicroRNA hsa-miR-1253:PITA hsa-miR-1253:PITA_TOP PITA 2.17E-19 1.21E-15 4.94E-19 4.55E-18 48 276 "SYNJ1,BTK,CHN1,ZFYVE16,ELMSAN1,EGR3,UBE2E3,FOXO3,CPLX2,GFRA2,TCERG1,GRB10,LINGO1,BACH2,LRRC75A,KIF5A,MEIS1,MSI1,NFIX,NPTX1,NTRK3,PDE1C,OLA1,DRAM2,CEP41,PEX2,NKAIN1,RGS4,SETD5,ROBO2,FBXW7,RTN1,SCN8A,PPM1E,R3HDM2,NLGN1,WDR47,SOX11,TTBK2,ANKRD28,CAMTA1,ADGRL3,NDRG4,TCEAL7,REEP1,MAP3K12,TMEM178A,KAT6A" MicroRNA hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA_TOP PITA 2.22E-19 1.24E-15 5.06E-19 4.66E-18 45 243 "OGT,PKP4,PTBP2,CAMK2G,USP6,COL9A1,CS,AATK,SOCS5,DGKG,SCRN1,MBNL2,COPS4,EPB41L2,RCAN2,SRRM1,FOXO3,AFF2,PCDH17,PRRC2B,GPD2,FAM19A2,SOX21,CELF5,SMAP1,MEIS1,MYCN,ZC3H12B,PCDH8,PDE1C,NUDT11,R3HDM2,WDR37,PPP4R3A,CPEB4,TMCC1,MYCBP2,SSTR2,PLCB1,SYN2,PUM2,CSMD1,NAV3,MSRB3,RNF146" MicroRNA hsa-miR-501-3p:TargetScan hsa-miR-501-3p TargetScan 2.35E-19 1.31E-15 5.34E-19 4.91E-18 36 153 "ACTN1,NDRG3,OGT,APC,PDE8B,BCL7A,PTBP2,RUNX1T1,CBFA2T2,DCLK1,DLGAP2,OSBPL3,FAM131B,KIAA0408,CPEB2,PCDH17,RAB30,CIT,PSIP1,AGFG1,MGAT3,MYCN,CLDN11,PPP2R2C,PPP2R5E,RPL15,SCN2B,FAM126B,PDZD2,PEG10,ITGB3BP,DOK6,EML6,EVI5,FXR1,GAN" MicroRNA hsa-miR-502-3p:TargetScan hsa-miR-502-3p TargetScan 2.35E-19 1.31E-15 5.34E-19 4.91E-18 36 153 "ACTN1,NDRG3,OGT,APC,PDE8B,BCL7A,PTBP2,RUNX1T1,CBFA2T2,DCLK1,DLGAP2,OSBPL3,FAM131B,KIAA0408,CPEB2,PCDH17,RAB30,CIT,PSIP1,AGFG1,MGAT3,MYCN,CLDN11,PPP2R2C,PPP2R5E,RPL15,SCN2B,FAM126B,PDZD2,PEG10,ITGB3BP,DOK6,EML6,EVI5,FXR1,GAN" MicroRNA hsa-miR-518e:mirSVR_highEffct hsa-miR-518e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-19 1.38E-15 5.61E-19 5.17E-18 38 172 "ZNF608,STK33,PCDHGB4,BARD1,JAZF1,SGCE,CFAP410,CCPG1,ARHGAP22,COL9A1,ZNF521,CSNK1G3,FHL1,IP6K2,MEGF11,SULT1C4,SYTL4,KITLG,PCDHGC3,KDM4C,TROVE2,KLHL7,PLCB1,MCF2L,AGTPBP1,WSCD1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA2,RIMBP2" MicroRNA hsa-let-7f-5p:Functional MTI Functional MTI miRTarbase 2.54E-19 1.42E-15 5.77E-19 5.31E-18 58 397 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,ATP2A2,ALDH7A1,BACH1,CALM1,USP2,CNOT8,ARMC8,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,MTSS1L,TRMO,PDLIM5,CELF1,GALC,DISC1,GATM,COPS8,MSL3,GLUL,POLL,FUT10,RABL2A,ATXN2L,IL6R,KPNA5,THYN1,SLC11A2,NUCB2,OPRL1,KLK6,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1" MicroRNA hsa-miR-631:mirSVR_highEffct hsa-miR-631:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-19 1.47E-15 5.98E-19 5.50E-18 59 410 "ADCY6,PHF12,PKP4,ATP2B2,SLC2A11,BACH1,RUNX1T1,MTMR7,MAGI1,CDO1,TPP1,AKAP7,COX4I1,SEC31B,HINFP,ANKRD44,SNCAIP,VCAN,ZC3H11A,DDX46,TMTC1,FAM13A,MRNIP,ZNF461,EVL,C2orf88,TVP23A,GABRG1,ZNF274,INPP5K,TCERG1,GLUL,HMGCL,STMN1,MAN2A2,MAT2A,EPDR1,HYDIN,PTPRE,SLC25A48,RET,SLC25A36,DGLUCY,AMBRA1,EPN2,KANSL3,SLC11A1,SLC12A2,ZFP1,BDP1,NXT2,NEK4,SYNE1,MTMR14,RASD2,SYNPO2,UGT8,CELF4,RNF103" MicroRNA hsa-miR-30c-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-19 1.62E-15 6.58E-19 6.06E-18 69 544 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,SYNJ2,ISPD,SLC16A4,EPS15L1,SUMF2,UBXN2A,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,PLEKHA1,MRNIP,MTSS1L,IGSF6,RACK1,ANKFY1,TRAF3IP2,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,SDK2,RETREG2,PPARA,MTMR10,PTPRE,CEP97,SETD5,KLHDC8A,MYO18A,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5" MicroRNA hsa-miR-484:PITA hsa-miR-484:PITA_TOP PITA 2.95E-19 1.65E-15 6.71E-19 6.18E-18 36 154 "PCDH19,SEMA4G,CBARP,CNTFR,SEC24C,RIMS2,RHOBTB1,DPP6,DPYSL2,PHC2,EGR3,EIF4G2,RASGRP2,FGF1,FHL1,UBE2E3,SPIN1,GRB10,MAP4K5,ZIC5,MAP2,GIT1,RETREG1,CEP41,TMEM260,PTPRE,RET,PRRT2,GTDC1,CYB561D1,MYCBP2,TBL1X,THRA,TRPS1,ZIC1,TMEM237" MicroRNA hsa-miR-29c*:mirSVR_lowEffct hsa-miR-29c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.00E-19 1.68E-15 6.81E-19 6.27E-18 44 234 "ADD1,SYT13,CAPN3,CSF2RA,RIMS2,YTHDC1,SGSM2,DOCK2,PHC2,FAM13A,RGS17,ZNF589,KHDRBS3,CGREF1,KDM2B,INSM1,KCNJ5,KTN1,MAP4,MEIS2,PCDH9,MAGEL2,NKAIN4,MASP1,PTPRB,NKAIN1,RASGRF2,EXD2,CCDC102B,NEK11,TNFRSF19,SEC14L1,PPM1E,CPEB4,ZNF423,SPTAN1,SEPT3,MLST8,EXOC7,SATB2,CLASP1,FAM189A1,TPM1,USP1" MicroRNA "ACACTGG,MIR-199A:MSigDB" "ACACTGG,MIR-199A:MSigDB" MSigDB 3.04E-19 1.70E-15 6.88E-19 6.34E-18 35 145 "RALGAPA1,PLEKHH1,ANK2,PRX,ATP2B2,FUBP1,MYRF,DDR1,LARGE1,CREM,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,ERBB4,ZNF44,GCNT2,CSDC2,PPARGC1A,GRB10,HLF,GIT1,PDE4D,PPM1B,RORB,ATXN7,ST6GAL1,LARP4,SIRT1,ZNF17,WNK3,ADAMTSL3" MicroRNA "ACACTGG,MIR-199B:MSigDB" "ACACTGG,MIR-199B:MSigDB" MSigDB 3.04E-19 1.70E-15 6.88E-19 6.34E-18 35 145 "RALGAPA1,PLEKHH1,ANK2,PRX,ATP2B2,FUBP1,MYRF,DDR1,LARGE1,CREM,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,ERBB4,ZNF44,GCNT2,CSDC2,PPARGC1A,GRB10,HLF,GIT1,PDE4D,PPM1B,RORB,ATXN7,ST6GAL1,LARP4,SIRT1,ZNF17,WNK3,ADAMTSL3" MicroRNA hsa-miR-6880-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-19 1.73E-15 7.03E-19 6.47E-18 51 313 "ABCF1,RNF157,HACE1,TAOK1,PDZD4,PHF12,PTBP2,CBS,CFL2,NRXN3,CSNK1E,GAPVD1,DNAL1,SGSM2,DUSP9,MRO,MTSS1L,MRPL10,FGFR1,NEURL4,MTHFD2,CSDC2,GLYR1,PRRC2B,IGF1,PPM1L,MKLN1,MXI1,PKM,PLCD1,PLEC,FXYD1,PLXNB1,NCR3LG1,MTMR10,PGBD4,FAM161B,NCBP3,STUM,PEG10,DBNDD2,CDK19,ASTN2,AGTPBP1,HIF3A,NACC2,LAT2,ZNF17,SLC38A1,EVI5,PARP11" MicroRNA hsa-miR-6511a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-19 1.81E-15 7.32E-19 6.74E-18 66 504 "ABCF1,XKR4,ELFN2,HECW2,TRMT9B,SHROOM2,ARHGDIA,DNAH17,DDR1,ISPD,CBFA2T2,NRXN3,AKAP5,UBXN2A,TMEM170A,DNAL1,EBI3,RASA4,MRNIP,MTSS1L,IGSF6,ANKMY1,KATNAL1,ZNF589,VTI1B,TRMO,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,FERMT2,KAT7,DDX19B,ZNF546,RBPJ,IBA57,COMMD5,NBL1,CNOT4,CCSER2,PLXNB1,RETREG2,POLR2F,QDPR,ZNF793,SCN2B,CPEB3,MYO18A,ATF7IP,ZSCAN29,NEK4,SLC37A2,FAM208A,SATB2,NACC2,PPIL6,UBTF,ZNF708,ZNF70,AMZ1,DPYSL5,EVI5" MicroRNA hsa-miR-188-5p:PITA hsa-miR-188-5p:PITA_TOP PITA 3.28E-19 1.83E-15 7.42E-19 6.83E-18 40 193 "ASIC1,ZNF578,OGT,BCL7A,CACNA1A,PCYT1B,TCAF1,HDAC4,MTX3,SLC12A6,NBEA,TPPP,KAT7,ADAMTS6,FRMD5,NKD1,INSM1,MBNL1,MEF2C,MGAT3,MXI1,ZC3H12B,PCDH9,PTX3,USP47,ZFHX4,FBXW7,FNIP1,KIF16B,FBXO11,TRIM67,SLC12A2,TET1,EPC1,LMO3,LARP4,ERBIN,ANKRD12,CAMTA1,SOCS4" MicroRNA hsa-miR-337-3p:PITA hsa-miR-337-3p:PITA_TOP PITA 3.28E-19 1.83E-15 7.42E-19 6.83E-18 40 193 "OSBPL8,ALCAM,ZBTB10,WASF1,THSD7A,CAMK2G,AKAP5,SLC35F1,RBM39,APPL1,PUM1,KCTD8,E2F5,TENM1,ERBB4,NRN1,PSD2,HLF,JAK2,MEF2C,MEIS2,CNOT4,NTRK3,PTPRN2,TTC13,ZFHX4,RORB,CPEB3,CCDC88A,SP4,LARP4,PRRC2C,SYN2,SYT1,CAMTA1,TCF4,EIF4ENIF1,TMEM237,FXR1,FRMD6" MicroRNA hsa-miR-122*:mirSVR_highEffct hsa-miR-122*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.35E-19 1.88E-15 7.58E-19 6.98E-18 43 224 "ACADM,CDC14B,KALRN,RUNX1T1,CERS5,ARMC8,COL11A2,HAPLN1,SOCS5,ARMCX4,SPOCK3,ARRDC4,AASS,LRRC17,CAMKK2,MSTN,LUZP2,GRIA2,KTN1,MAT2A,POC1B,BLOC1S2,TBC1D25,KCTD15,GPSM2,TMEM255A,USP47,SETD5,ROBO2,SNAP25,BDP1,TSPYL2,RBM26,TROVE2,ELOVL4,SYP,RPGRIP1L,DCBLD1,RICTOR,PCDH20,ZBTB14,LYPD6,TRIM16L" MicroRNA "GTGCAAA,MIR-507:MSigDB" "GTGCAAA,MIR-507:MSigDB" MSigDB 3.54E-19 1.98E-15 8.01E-19 7.37E-18 33 128 "SLC24A4,PCDH19,UNC79,NCOA1,ATP2B2,LONRF1,KMT5B,EIF4G2,RGS17,BACH2,AGFG1,KCND2,MARK3,MBNL1,MEIS1,NELL2,PAX6,PCDH9,USP47,REV3L,PBRM1,FBXW7,SEMA6D,CHD9,DHX30,TET1,CPEB4,HECW1,IQSEC2,ANKRD12,ADGRL3,THRA,ZIC1" MicroRNA hsa-miR-758:PITA hsa-miR-758:PITA_TOP PITA 3.71E-19 2.08E-15 8.40E-19 7.73E-18 36 155 "INTS2,CDC42BPA,MAP4K3,ATP2B2,BMP7,RUNX1T1,MAGI1,QKI,MAP4K4,APPL1,RASGRP1,CLVS1,SPSB4,NBEA,APOPT1,TVP23A,SRRM4,BACH2,HLF,MEIS2,ANKRD16,STRN3,RELN,OXR1,ZC3H14,CPEB4,STXBP1,CUX2,PUM2,ZFPM2,TIAM1,ZBTB38,REEP1,EMSY,RNF103,FRMD6" MicroRNA "ACTGTAG,MIR-139:MSigDB" "ACTGTAG,MIR-139:MSigDB" MSigDB 4.04E-19 2.26E-15 9.14E-19 8.41E-18 32 120 "TAOK1,PCDH10,LRCH2,ANK2,ZBTB10,ATP2B2,CACNA2D2,DMD,TSPAN5,EIF4G2,STAU2,FREM1,PPARGC1A,HMGCR,MAP2,MAT2A,MEIS2,NPTX1,PDE3A,PDE4A,PMP22,SCHIP1,ZNF532,LRFN5,WDR47,CPEB4,SMARCA4,TMCC1,CDK19,TROVE2,TCF12,NDRG4" MicroRNA hsa-miR-296-3p:Functional MTI Functional MTI miRTarbase 4.32E-19 2.42E-15 9.77E-19 8.99E-18 46 258 "MTA3,PITPNM2,SHROOM2,CA8,SEPT7,CDC25B,ZBED1,SMARCAL1,PUM1,PYGO1,DCAF8,ADGRV1,TUBA1B,RACK1,SEC24B,FGFR1,TRMO,SRCAP,CRCP,TCERG1,GLUL,PRRC2B,CCDC184,LSAMP,MPP2,PKM,POLG,PPP1R1A,MAPK7,ZNF844,ZFHX4,FBXW7,ATAT1,SATB1,SBF1,FAM102A,ZNF667,ZNF621,DICER1,TSC2,UBC,ZNF781,ZNF138,ITM2C,KAT6A,GAN" MicroRNA hsa-miR-526b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.33E-19 2.42E-15 9.79E-19 9.01E-18 45 247 "OGT,APBB2,LGR5,SEMA4G,ARSE,AP1M1,C1orf52,CDC25B,DLGAP2,CDR1,CLOCK,SUSD5,APPL1,EPHB1,ST3GAL6,FGF1,SYNCRIP,FAM49B,STAMBP,KIAA1841,GPR75,FUT10,TPPP,KLHL23,LIFR,LOH12CR2,TM6SF1,XRRA1,TMOD2,ENOX1,ARMH4,ST6GAL1,CXXC4,RCOR3,CDK19,ASTN2,MGRN1,ZMAT3,ARL10,TLR4,TRPS1,ZNF24,CADM2,KCNAB1,NETO2" MicroRNA hsa-miR-623:PITA hsa-miR-623:PITA_TOP PITA 4.59E-19 2.57E-15 1.04E-18 9.55E-18 33 129 "CCDC85A,SLC4A4,CACNA1A,CALM1,DCLK1,TAOK2,HAPLN1,RIMS4,EBF1,CELSR3,EIF1,NCALD,CIT,RNF165,ADAMTS6,NKD1,CYP27C1,MBNL1,MEIS1,MEIS2,NTRK3,GPR85,PIK3R1,PTPRD,PRRT2,ZNF821,NLGN1,SLC12A2,EPC1,UNC5B,SEPT3,TRIM2,TCF12" MicroRNA hsa-miR-933:mirSVR_lowEffct hsa-miR-933:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-19 2.68E-15 1.08E-18 9.96E-18 56 377 "PWWP2A,PTCHD1,AP2A2,CC2D2A,ZNF687,PDZD4,AMPD2,APAF1,CDK10,ZFYVE28,ARNTL,BBS2,CBLN1,CBR1,P2RX6,ARHGEF6,COL11A2,ABI3BP,TBPL1,PDE4DIP,GREB1,SPOCK3,SLC29A4,TVP23A,PCLO,GRIN2D,GRM2,AGBL5,AQP11,XRRA1,HNRNPM,NINJ2,CNOT4,OCRL,FAM216A,PRKACB,MAPK4,BCAS3,ZFHX4,YY1AP1,PCMTD2,ST6GALNAC6,FAM102A,WDR37,PEX26,SMARCD3,ATP10B,ARHGEF9,TIAM1,PIK3R5,C9orf85,FAM155A,PLPPR2,UBE3B,FBXO36,JMJD1C" MicroRNA hsa-miR-5006-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.07E-19 2.84E-15 1.14E-18 1.05E-17 46 259 "AS3MT,XKR4,MTA3,SORCS2,AK2,SPOP,SEMA4G,ASGR1,BCL7A,BID,CACNA1G,MYRF,LURAP1,CAMK2G,RGS6,IPCEF1,CHRDL1,RCAN1,FEM1B,CELSR3,AMOTL2,SRCAP,GLUL,TPPP,PTPRT,PADI2,NEGR1,EID2B,LSAMP,NOVA2,NPTX1,GLIPR1L2,KANSL1,MARCH1,SH3TC2,DPF2,RORB,ELP2,MYO18A,BTBD3,SLC11A1,ZBTB43,TOM1L2,ZNF177,ZDHHC20,DPF3" MicroRNA hsa-miR-340-5p:Functional MTI Functional MTI miRTarbase 5.43E-19 3.04E-15 1.23E-18 1.13E-17 53 341 "OSBPL1A,WDR35,CC2D2A,ATP1A1,CALM1,ABCG2,QKI,CRY2,RIMS4,APPL1,UBXN2A,GREB1,PUM1,MTX3,FEM1B,CERCAM,C8orf37,RCAN2,TUBB3,SCML2,DLC1,FOXO3,C15orf41,LYVE1,ATXN2L,ZIC5,SLC35G1,LIFR,LIMS1,HECTD2,MAT2A,KCTD6,MITF,MKLN1,IGSF11,PDE4D,PDZRN4,SNRK,PTPRD,PEX2,REV3L,FIGN,TMLHE,MCMBP,CLIP1,SLC6A8,SYPL1,PUM2,KAT6B,TNS1,ZXDA,SLC38A1,GAN" MicroRNA hsa-miR-1304-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-19 3.47E-15 1.40E-18 1.29E-17 67 524 "CLK4,TMEM132B,TEX22,MTA3,PHF12,CDC14B,BMP7,ZBED1,DIS3L,RTTN,RNF14,HINFP,UBXN2A,SEC14L5,DBN1,DBT,ZBTB24,KRBA2,HEYL,IRAK4,MRNIP,RGS17,TUBD1,COQ7,SLC43A2,IGSF6,FGFR1,SEC23B,APOPT1,MSANTD4,DBF4,KDM2B,RAB40B,LILRA2,ATOH8,DDX19B,ZNF546,NKD1,IL6R,IBA57,CYP27C1,LIMS1,GPR155,SAMD5,ZDHHC8,ZNF655,ZNF426,STRN3,EXOSC10,FITM2,APTX,PIGG,MTMR10,ELP2,PEX26,ZNF430,ATF7IP,BDP1,KLHL7,SLC37A2,ALG1,TPCN2,PCDHA6,ZNF106,ARL10,FAM124A,ZNF708" MicroRNA hsa-miR-6513-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-19 3.61E-15 1.45E-18 1.34E-17 57 392 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,PLEKHA1,MRNIP,IGSF6,ANKFY1,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,IRAK3,IGF1,STMN1,MATN3,CHST6,PPM1L,SLC11A2,OCRL,ZNF713,RETREG2,MINDY2,CNTLN,MTMR10,CEP97,GALNT10,SEPHS1,ZKSCAN3,FAM126B,MCF2L2,STAU1,ZSCAN29,FAM208A,SLC19A3,NSD1,PCDHA6,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20" MicroRNA hsa-miR-4755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.97E-19 3.90E-15 1.57E-18 1.45E-17 46 261 "AS3MT,XKR4,MTA3,SORCS2,AK2,SPOP,SEMA4G,ASGR1,BCL7A,BID,CACNA1G,MYRF,LURAP1,CAMK2G,RGS6,IPCEF1,CHRDL1,RCAN1,FEM1B,CELSR3,AMOTL2,SRCAP,GLUL,TPPP,PTPRT,PADI2,NEGR1,EID2B,LSAMP,NOVA2,NPTX1,GLIPR1L2,KANSL1,MARCH1,SH3TC2,DPF2,RORB,ELP2,MYO18A,BTBD3,SLC11A1,ZBTB43,TOM1L2,ZNF177,ZDHHC20,DPF3" MicroRNA hsa-miR-887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.08E-19 3.96E-15 1.59E-18 1.47E-17 63 471 "XKR4,PLEKHH1,TXNDC16,AQP6,DNAH17,SYNJ2,ISPD,SLC16A4,SUMF2,CLOCK,PPP1R16B,UBXN2A,USP6NL,MYADM,GAPVD1,DNAL1,DNAH9,SLC29A4,TMTC1,MRO,PLEKHA1,MRNIP,IGSF6,ANKFY1,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,IRAK3,MIER3,IGF1,TJAP1,SMAD9,MATN3,PPM1L,SLC11A2,OCRL,ZNF713,RETREG2,CNTLN,MTMR10,CEP97,KLHDC8A,GALNT10,MYO18A,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,SIGLEC10,ZDHHC20" MicroRNA hsa-miR-3680-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.63E-19 4.83E-15 1.94E-18 1.79E-17 38 178 "KCTD16,SEMA6A,BACH1,BCL7A,BID,CALM1,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,GUCD1,EDN1,STARD3NL,SLC43A2,ACSL4,SCML2,FER,PRRC2B,RBPJ,LIMS1,CHIC1,P2RY1,PDE3A,PLIN1,STRN3,ACSS3,NWD1,KCNIP3,SATB1,PEX26,TMCC1,SEPT8,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-208a:mirSVR_highEffct hsa-miR-208a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.06E-18 5.92E-15 2.38E-18 2.19E-17 38 179 "TMEM108,BLM,SYNJ1,PRC1,CDO1,QKI,MAP4K4,IQCK,ZNF804A,DDX46,PLPPR4,CPEB2,EDNRB,KCTD3,MED12L,ANKFY1,DISC1,CBX1,GRIA2,RNF165,HNMT,CELF5,TRHDE,PEX2,USP47,RIC8B,PNMA8A,TCP11L1,RYR3,CHD9,RCOR3,TTC17,ARHGEF9,SATB2,ZEB1,DOCK9,ERCC6L2,MICU3" MicroRNA hsa-miR-645:mirSVR_highEffct hsa-miR-645:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-18 5.97E-15 2.40E-18 2.21E-17 58 409 "KCNH8,PLEKHH1,PTCHD1,ZNF578,SFMBT2,DPY19L3,NRP2,ARHGEF7,IL33,PTBP2,RUNX1T1,MTMR7,SYNGR3,AP4M1,LRBA,IQCK,ARMC8,ZNF521,CREM,PUM1,HDAC9,GIT2,KIAA0319,DMD,DNAH9,SUGP2,RASA4,PAN3,SRRM1,NSRP1,FCGR1A,GABRG2,DCLK2,WDFY3-AS2,INPP5B,KCNN1,MITF,AFDN,NF1,SH3KBP1,ZSCAN32,ZDHHC4,ROBO1,PCMTD2,ANKRD6,SEPHS1,SLC8A1,HECW1,UNC5B,KLHL7,C12orf76,TCF12,CLASP1,FAM200B,XPO1,ZBTB38,CADM2,PARP11" MicroRNA hsa-miR-628-3p:PITA hsa-miR-628-3p:PITA_TOP PITA 1.13E-18 6.34E-15 2.55E-18 2.35E-17 36 160 "PCDH19,AMPD3,SYNJ1,BTK,JAZF1,PTBP2,SEPT7,MAP4K4,SLC35F1,GAPVD1,DYNC1I1,FRY,FSD1L,YAF2,PAN3,AFF2,PCDH17,MIER3,HLF,NEGR1,ZIC5,PACRG,MID1,HS6ST3,NEXMIF,PCDH9,EPB41L4B,PPP3CA,PBRM1,SLC8A1,TET1,SPTB,NKAIN2,RIMBP2,TRPS1,FAM155A" MicroRNA hsa-miR-4635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-18 6.89E-15 2.77E-18 2.55E-17 52 335 "TMCC3,KIAA1211,PARG,TNRC6C,SEMA4G,AP1M1,DGKI,DLGAP2,CLCN3,ABCG2,CLOCK,PHF14,PITPNC1,MYEF2,KLHL3,RGS17,NCALD,FER,POLR1B,CRCP,FUT10,TPPP,KCNN3,CREG2,LIFR,TM6SF1,CLDN11,PCDH9,TMOD2,MAPK9,NCR3LG1,KLHL11,ZNF568,ATXN7,FNDC3A,NUBPL,CPEB4,CXXC4,RCOR3,ANKRD36,FNBP1,SSTR2,ERBIN,SULF2,KLHL7,PCDHA6,ZNF106,CBX5,ZKSCAN5,ZNF225,MPPE1,GAN" MicroRNA hsa-miR-496:PITA hsa-miR-496:PITA_TOP PITA 1.24E-18 6.94E-15 2.79E-18 2.57E-17 37 170 "MTUS1,NCOA1,EIF4G3,WASF1,CALB1,CD86,CDH2,ZMYM4,FOXN3,QKI,ARHGEF6,DNM1,GPR34,MBNL1,SAMD5,NOVA1,LRP12,GTDC1,CPEB3,NLGN1,SEPHS1,ELMO2,CPEB4,TMCC1,SS18,ELOVL4,PLCB1,ANKRD12,FBXW11,DOCK9,SLC44A1,ERCC6L2,TRPS1,FLRT2,TOM1L2,PRTFDC1,FRMD6" MicroRNA hsa-miR-373-3p:Functional MTI Functional MTI miRTarbase 1.25E-18 7.01E-15 2.81E-18 2.59E-17 67 531 "FZD9,SORCS2,ZNF578,TAOK1,MARCH4,ATP1B3,BACH1,LDHD,PRC1,ZBED1,DIS3L,CFL2,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,PHC2,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CSDC2,CRCP,GRB10,HAS2,ZHX1,GPR155,MBNL1,PDPK1,TMEM38A,GPSM2,SLC25A23,ZNF426,PRKACB,FITM2,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,CDK19,STAC2,SATB2,GPRIN3,SIRT1,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1,DPF3" MicroRNA hsa-miR-337-5p:mirSVR_highEffct hsa-miR-337-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-18 7.01E-15 2.81E-18 2.59E-17 40 200 "ZFAT,ARNTL,SLC25A14,ZNF501,TIGD7,CNN3,COL11A2,CTH,HDAC9,HEPH,NR1D2,CPEB2,SUGP2,RPS6KC1,KAT8,ERAP1,CBX1,LNX1,GPD2,GRIN2D,AGBL5,SHISA6,SLC35G1,GATD1,NELL2,PRTG,PPP3CA,PIGG,PTPRO,PPP2R3C,SGK1,SH3BGR,SYBU,NLGN1,SLC44A1,CCDC14,ZBTB38,ZNF195,AMN1,KAT6A" MicroRNA hsa-miR-297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-18 7.25E-15 2.91E-18 2.68E-17 39 190 "TMEM132B,HACE1,TAOK1,CFL2,IGLON5,MYADM,DCAF8,SV2B,DMD,MBNL2,CERCAM,KATNAL1,UBE2E3,GABRG1,GATM,SESN1,MMADHC,CBX1,BVES,ZDHHC15,IGF1,KCNQ3,MKLN1,MYO5A,NELL2,SDK2,RIC8B,PGBD4,SATB1,CSRNP3,PEX26,NECAB1,ARHGEF9,PLCB1,CSMD1,KCNK12,ZNF711,ZNF195,ADAMTS9" MicroRNA hsa-miR-431*:mirSVR_lowEffct hsa-miR-431*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-18 7.75E-15 3.11E-18 2.86E-17 55 373 "LTBP4,AMPD2,LGR5,MARK4,VXN,RHBDL1,CCNH,ENTPD6,ASIC3,RCHY1,ANKRD44,SNCAIP,FAM131B,MFAP3L,SV2B,GRIN3A,TOM1,YAF2,ELN,NCALD,PRMT5,APOPT1,BRSK1,IQGAP2,DISC1,GPR162,MSL3,ATXN2L,HNF4G,HSF2,SCIN,MBD1,MBNL1,SH3KBP1,TMEM260,PTPRE,ACSS3,RFX2,C12orf49,LRRK2,ATAT1,SCP2,SEC14L1,SUPT5H,SLC37A2,TACC1,ARHGAP9,SIK3,ACTR6,GUSBP1,LGI4,ZIC1,DHX33,EVI5,LAS1L" MicroRNA hsa-miR-147b:mirSVR_lowEffct hsa-miR-147b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-18 7.86E-15 3.15E-18 2.90E-17 52 336 "FAHD2CP,PHYHD1,RGS9,ARHGEF7,BAIAP3,VXN,C4orf33,RAB26,SH2B1,PLXNA4,INTS1,ARRDC4,MTSS1L,FGFR1,IP6K2,SEMA4D,TVP23A,IP6K3,GHDC,IGSF5,PPARGC1A,GLI2,CIT,BTN2A1,TJAP1,MEIS1,PAX6,PMP22,PPP2R2C,WDR25,TMEM260,EML5,USP47,SUSD4,GTDC1,RNH1,ZNF331,SCN8A,PRCD,SLC12A4,LGI3,MAPKBP1,SNRPN,SOX15,ZSCAN29,SYT5,SLC44A1,BHLHB9,DCBLD1,KCNE5,TRIM9,DOCK8" MicroRNA hsa-miR-483-3p:PITA hsa-miR-483-3p:PITA_TOP PITA 1.45E-18 8.09E-15 3.24E-18 2.98E-17 30 108 "ADCY6,OGT,APBA2,BCL7A,CAMK2G,QKI,MFAP3L,FAM13A,PAN3,DLC1,FGF12,GHR,SPIN1,BACH2,IGF1,CAMK2N2,MAP2,NTRK3,RASGEF1B,SATB1,FNIP1,CPEB3,AMBRA1,SLC6A8,RCOR3,FAM126B,EXOC7,R3HDM1,UBTF,XPO1" MicroRNA hsa-miR-4292:mirSVR_highEffct hsa-miR-4292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-18 8.35E-15 3.34E-18 3.08E-17 57 399 "FAHD2CP,MTUS1,PKP4,N4BP2L1,CARMIL3,DST,CERS5,CNTFR,CLIP3,SNCAIP,ARHGAP24,TM9SF4,TBC1D5,ARMCX4,RHOBTB1,CHRDL1,SLC29A4,ACOT8,SNX29,PHF20L1,DCTN4,ERBB2,EYA1,ZNF589,FGF1,IQCG,NBEA,AK8,HHIPL1,TMEM8B,GHR,KAT7,ARHGAP36,KNDC1,KCNH2,STXBP5,MAT2A,TREM2,SEMA5B,SEPT4,MAPK10,SLC26A11,PTPRE,RORB,RPE,SH3BGR,EPN2,WDR47,CCDC88A,SS18,RPGRIP1L,RPL7L1,UGT8,OSBP2,ADAMTS9,ST7,CASC15" MicroRNA hsa-miR-1273c:mirSVR_lowEffct hsa-miR-1273c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-18 8.51E-15 3.40E-18 3.13E-17 46 266 "ZNF578,SEMA6A,PITPNM2,PHF12,VAT1L,SHROOM2,MARCH3,CACNB4,CALM1,TBPL1,PDE4DIP,PHF14,HDAC4,GIT2,ABCC5,TMTC1,EIF4G2,PAN3,PSD2,GFRA2,PPARGC1A,ZNF276,AP4S1,LMO2,MEF2C,PCDH9,OLA1,PPM1B,ACSM5,ROBO1,SALL1,ATXN7,FNDC3A,SSTR1,MTCL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,XPO1,NAV3,SOCS4,CPNE4" MicroRNA hsa-miR-636:PITA hsa-miR-636:PITA_TOP PITA 1.58E-18 8.85E-15 3.54E-18 3.26E-17 38 181 "ABR,ACTN1,RTL9,OSBPL8,SEMA6A,NUMB,DPY19L3,DCLK1,HAPLN1,PUM1,USP6NL,GAPVD1,DNAJB6,MBNL2,PAN3,EMX2,NRN1,RNF165,FAM222A,ATXN2L,BACH2,LIFR,NOVA1,PCDH9,LRP12,QRICH1,TMEM260,FAM214B,CEP68,PLCB1,SYT1,TCF4,DOCK9,FRYL,TNS1,TRIM9,KAT6A,MSRB3" MicroRNA hsa-miR-1228:PITA hsa-miR-1228:PITA_TOP PITA 1.58E-18 8.85E-15 3.54E-18 3.26E-17 38 181 "CCDC85A,DPP10,PKP4,JAZF1,LDLRAD4,USP6,DLGAP2,SOCS6,IGDCC3,CLOCK,CRY2,CSNK1G3,TMEM35A,EYA1,C15orf41,TCERG1,TNRC6A,BACH2,ZIC5,ZC3H12B,MAPK10,PTPRD,ZFHX4,CASC3,CPEB3,CPEB4,FAM219A,SOX3,SS18,TTBK2,RGL1,SYT1,CAMTA1,TPM1,TSC1,USP1,POLR3H,ST8SIA2" MicroRNA "GACAATC,MIR-219:MSigDB" "GACAATC,MIR-219:MSigDB" MSigDB 1.62E-18 9.08E-15 3.63E-18 3.34E-17 33 134 "KCNH8,FMNL2,ADD2,RTL9,SEMA4G,NCOA1,CAMK2G,CPEB2,EGR3,EYA1,PCDH17,PPARGC1A,TTBK1,MAPT,ZC3H12B,OCRL,ZNF827,PDE4D,PURG,PDZRN4,TRHDE,ING3,SNRK,RORB,CPEB3,BTBD7,SP4,MCF2L2,SYT5,TACC1,NR2C2,UBE3A,SLC30A4" MicroRNA hsa-miR-615-5p:mirSVR_highEffct hsa-miR-615-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-18 9.13E-15 3.65E-18 3.36E-17 51 325 "SYN3,SYS1,AMH,DDR1,TBRG4,PLEKHB1,RAB33A,LETMD1,ABI3BP,SMARCAL1,CLIP3,CS,SNCAIP,MYEF2,DMPK,DMTF1,CELSR3,ELN,HSPA12B,SUCO,SYT3,APOPT1,USP19,LILRB4,GRIK5,MAN1B1,NKD1,ZNF678,ITGA7,CAMK2N2,LRP1B,MEIS2,MT1M,TMEM38A,PLTP,PPP5C,MAPK10,MASP1,RGS4,PKNOX2,ZSCAN29,CEP68,C12orf76,SATB2,RNF216P1,ITGB3BP,CDH22,STXBP4,HSPBP1,MEIS3,PRDM8" MicroRNA hsa-miR-519c-3p:Functional MTI Functional MTI miRTarbase 1.76E-18 9.86E-15 3.94E-18 3.63E-17 53 350 "TAOK1,SEMA7A,CFL2,EPS15L1,CLCN3,ABCG2,QKI,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,CERCAM,C3orf18,KATNAL1,ACSL4,FKTN,POLR1B,SEC23B,CELF1,GRB10,FICD,KCNB1,MBNL1,NBL1,CNOT4,PPARA,CEP97,RBBP6,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,ATMIN,SATB2,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-18a-3p:Functional MTI Functional MTI miRTarbase 1.76E-18 9.86E-15 3.94E-18 3.63E-17 53 350 "TEX22,SEMA4G,PRX,BCS1L,ARHGEF7,DIS3L,TOGARAM2,CPS1,CRY2,DBN1,YTHDC1,USP3,MRPL37,CD320,SEC24B,FGF11,SEC23B,IP6K2,ATP2C1,CELF1,NEURL4,KIAA1841,SRCAP,GFER,TXNL4A,GPD1,FAM107A,ATXN2L,ACOT7,AGFG1,LIMS1,MBD1,HNRNPM,PDE4A,PKM,KCTD15,PIGG,PTPRN,KLHL11,FNIP1,HSPA4L,ST6GAL1,KBTBD4,MAPKBP1,STAC2,PHLDB1,EXOC7,KIAA0930,PCDHGC5,RPL7L1,UBTF,ITM2C,RNF170" MicroRNA "CCAGGGG,MIR-331:MSigDB" "CCAGGGG,MIR-331:MSigDB" MSigDB 1.86E-18 1.04E-14 4.16E-18 3.83E-17 28 93 "AP2A1,SEMA6A,NRP2,KSR1,USP2,TAOK2,RIMS4,ELMSAN1,FAM78B,PHC2,EGR3,BAIAP2,NBEA,GABBR1,CPLX2,GGT7,PLPP7,ATOH8,ATXN2L,MEIS1,MEIS2,KCTD15,C1orf109,RIC8B,EXOC7,RELL2,POLR3H,PRDM8" MicroRNA hsa-miR-219-5p:PITA hsa-miR-219-5p:PITA_TOP PITA 1.88E-18 1.05E-14 4.19E-18 3.86E-17 37 172 "KCNH8,FMNL2,PITPNM2,SEMA4G,NCOA1,CAMK2G,AKAP6,CNRIP1,AKAP12,RHOBTB1,CDON,CPEB2,EGR3,EYA1,PCDH17,PPARGC1A,TTBK1,MIER3,MEF2C,OCRL,ZNF827,PDE4D,PURG,PDZRN4,TRHDE,SNRK,RORB,RXRA,CSRNP3,HSPA4L,CPEB3,SP4,ARHGAP26,SYT5,TACC1,NR2C2,UBE3A" MicroRNA hsa-miR-491-5p:Functional MTI Functional MTI miRTarbase 1.88E-18 1.05E-14 4.19E-18 3.86E-17 37 172 "CASKIN1,TRMT9B,AMPD3,ARRB1,ARRB2,PYGO1,ABCC5,APH1A,EGFR,MRO,ING4,ELN,SEPT9,SESN1,MIER3,SHISA6,SOWAHA,MAP4,GIT1,GPR173,PFKFB2,PKM,PLEC,SLC25A23,SDK2,KIAA0895L,SBF1,ATXN2,BTBD3,KDM4B,PEG10,CAMTA2,SLC19A3,NACC2,UBTF,ZNF708,ZNF138" MicroRNA hsa-miR-7151-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-18 1.06E-14 4.22E-18 3.88E-17 57 401 "CLK4,ESYT2,TAOK1,ATP1B3,SLC2A11,LDHD,ZMYM4,DIS3L,PLAA,LETMD1,RNF14,SOCS5,SLC12A6,EIF4G2,IRAK4,MRNIP,TUBD1,COQ7,SLC43A2,TUBA1B,CEP78,FDFT1,GTF2IRD2,ZNF44,TRAF3IP2,TXNL4A,RNPS1,ZNF491,NKD1,IL6R,SLC6A17,METTL21A,CYP27C1,LAMP2,MAT2A,MBD1,CHST6,ZNF426,MINDY2,SETD5,C12orf49,HSPA4L,SGK1,FAM126B,SP2,ZNF621,PBLD,DIP2A,ZMAT3,CBX5,PARD3,RPL7L1,CFAP298,ZNF70,SIGLEC10,MPPE1,AP3B2" MicroRNA hsa-miR-650:Functional MTI Functional MTI miRTarbase 1.90E-18 1.06E-14 4.23E-18 3.90E-17 59 427 "ABCF1,NDRG2,ADD2,TRMT9B,CPNE5,ARHGDIA,DDR1,LETMD1,CRY2,NCOR2,IPCEF1,RASSF2,LIN54,TMEM170A,DNAL1,SGSM2,SEC16A,RASA4,ING4,MRNIP,ANKMY1,KATNAL1,MRVI1,TRMO,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,DDX19B,IBA57,KLHL23,SAMD5,NBL1,TMOD2,PLEC,PLXNB1,RETREG2,ZNF793,SETD5,NCBP3,FAM102A,TRIM67,ATF7IP,ERC1,PEG10,IQSEC2,ZSCAN29,USP22,PPIL6,SSBP2,ZNF70,INTS3" MicroRNA hsa-miR-504:mirSVR_highEffct hsa-miR-504:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.00E-18 1.12E-14 4.46E-18 4.11E-17 55 376 "CLK4,KLHL32,ZNF608,TAOK1,ALCAM,PCDH10,CDK10,CFLAR,IL33,LURAP1,KALRN,CBARP,SUMF2,ANKRD44,UBXN2A,RUSC2,DPYSL2,MBNL2,COPS4,DLC1,SEMA4D,CELF1,CHL1,PCDH17,LYVE1,STARD3,ZNF638,GPR12,SMAP1,SOWAHA,BLOC1S2,MYO7A,MYO9A,CNOT4,SLC10A4,TMEM38A,NLE1,PLCB2,PLCL1,MINDY2,CYBC1,SH3TC2,MCMBP,COPZ1,ASAP3,BTBD7,NXT2,ASTN2,ZMAT3,TSC1,OSBP2,FSTL5,HPS4,GAL3ST3,ADAMTSL3" MicroRNA hsa-miR-660-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-18 1.12E-14 4.46E-18 4.11E-17 55 376 "RNF157,ADD1,SLC4A4,GPR146,STOML1,IGLON5,RTTN,LRIG1,PDE4DIP,DBN1,ZBTB24,RUSC2,C2CD2L,RASA4,RGS17,TUBD1,TMEM132C,CHST15,FKTN,PCDH17,KIAA1958,ZDHHC15,C2CD4C,METTL21A,LSAMP,GPR155,MAT2A,AFF1,SAMD5,ALDH1L2,MTRF1L,KANSL1,FITM2,APTX,ZSCAN2,GTDC1,CYB561D1,RXRA,STX1B,PEX26,BDP1,FAM208A,ALG1,AGTPBP1,ZNF106,ARL10,PARD3,SSBP2,RPL7L1,LAT2,DPYSL5,ZNF195,SIGLEC10,FAM13C,RNF170" MicroRNA hsa-miR-143-5p:Functional MTI Functional MTI miRTarbase 2.08E-18 1.16E-14 4.63E-18 4.26E-17 56 389 "ABCF1,CLK4,XKR4,ESYT2,DOCK11,ST3GAL5,AKAP5,TBPL1,DBT,YTHDC1,KRBA2,HEYL,OPTN,TUBD1,ENPP6,SEC23B,AFF2,SPECC1,MSANTD4,TRAF3IP2,TNRC6A,KAT7,FICD,IBA57,LIMS1,GPR155,MAT2A,MKLN1,AFF1,OLA1,ZNF655,GPSM2,FITM2,PEX2,PGBD4,SNX22,NCBP3,HSPA4L,PEX26,ANKRD36,ERC1,ZNF621,ZSCAN29,KLHL7,ALG1,MGRN1,ZNF106,THRA,AGMO,ZNF74,ZNF138,ZNF154,TIGD6,RNF170,NETO2,RNF146" MicroRNA hsa-miR-125a-5p:mirSVR_highEffct hsa-miR-125a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.97E-18 1.66E-14 6.61E-18 6.09E-17 62 471 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,ARNTL,CDK13,ZBTB10,USP2,P2RX6,SULT4A1,LY86,SLC4A8,HINFP,KIAA0586,IST1,SRRM1,SPEG,SEMA4D,CGREF1,OGA,KIAA1841,RABL2A,AGBL5,MSL1,ZNF546,KCNB1,KCNN2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,TMLHE,ATP8B4,COPZ1,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,SEPT8,DIP2A,C18orf54,MTMR14,TLR4,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,EPM2A,TIGD6,IFT88" MicroRNA hsa-miR-450a-1-3p:Functional MTI Functional MTI miRTarbase 2.97E-18 1.66E-14 6.62E-18 6.09E-17 56 392 "XKR4,PLEKHH1,TXNDC16,DNAH17,LDHD,SYNJ2,ISPD,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,PLEKHA1,MRNIP,IGSF6,ANKFY1,MSANTD4,TRAF3IP2,CRCP,GNG4,IRAK3,IGF1,MATN3,PPM1L,SLC11A2,OCRL,ZNF713,PDE3A,RETREG2,PRKAB2,CNTLN,MTMR10,CEP97,SETD5,GALNT10,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,NACC2,ERCC6L2,UBC,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20" MicroRNA hsa-miR-27a*:mirSVR_highEffct hsa-miR-27a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.98E-18 1.67E-14 6.62E-18 6.09E-17 59 431 "DPY19L2P4,ZNF608,HECW2,HFM1,FAM135A,BCAS1,SEMA4G,RNF182,DST,LARGE1,CNR1,CNTFR,ENTPD4,CLIP3,PDCD6IP,DNM1L,EIF5,TENM1,TMEM35A,SRRM1,PRMT5,NELFCD,C2orf88,USP21,DLL3,MSL3,KDM2B,ADGRA3,BTN2A1,HLF,INPP5B,ITPKB,KCNJ16,STXBP5,L1CAM,LAMP2,SLC11A2,CLDN11,HYDIN,MASP1,BCAS3,VPS13C,PTK2,ENOX1,CARF,SNX22,ATXN2,SLC11A1,ZC3H13,SEPT3,KLHL4,PCDHB4,ASXL3,PCDH20,EMSY,DNALI1,RGS7BP,IFT88,CPNE4" MicroRNA hsa-miR-433-3p:TargetScan hsa-miR-433-3p TargetScan 3.08E-18 1.72E-14 6.84E-18 6.30E-17 43 237 "INTS2,HECW2,ATP6V0A1,FOXN3,CLCN3,CLTC,QKI,NSL1,CCDC144A,PYGO1,MTX3,FSD1L,ENPP6,ERBB4,EXTL2,KATNAL1,CELF1,CHL1,ALDH1L1,PPARGC1A,FERMT2,NEGR1,KPNA5,MN1,MXI1,GPR137C,PRKCB,CEP97,PBRM1,CCDC82,FBXW7,CLIP1,CHD9,NUBPL,EPN2,CMTR2,ANKRD12,FAM208A,NSD1,PLEKHH2,RBFOX3,GDPD5,GAN" MicroRNA hsa-miR-614:mirSVR_highEffct hsa-miR-614:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.14E-18 1.76E-14 6.98E-18 6.43E-17 40 205 "ACADM,CC2D2A,OGT,EPB41L5,PHYHD1,TMEFF1,QKI,NRG2,CNRIP1,SEC24C,DCAF4,WDR20,FCF1,MRPL37,PPP1R1B,FGF13,LUZP2,NCOA7,MAT2A,MYT1,NCAM2,GPR85,PFKFB3,ING3,SUSD4,RBBP6,NUDT11,TCP11L1,DGLUCY,MTERF2,CPEB4,PLCB1,SYP,DMXL2,MTMR14,SMARCAD1,EMSY,PDSS2,RGS7BP,NETO1" MicroRNA hsa-miR-202-5p:TargetScan hsa-miR-202-5p TargetScan 3.14E-18 1.76E-14 6.98E-18 6.43E-17 40 205 "ACTN1,BEND6,OGT,PKP4,DST,MYRF,RUNX1T1,CBFA2T2,CS,CSF1,KIAA0408,GIT2,JAKMIP2,PLEKHA1,PAN3,EPB41,SCARA3,HLF,MSL1,LSAMP,GPR155,MATN2,MEIS2,PPP5C,PTPRG,MARCH1,KHDRBS2,RGS3,AP1AR,ATXN2,SCN2B,CPEB3,EPC1,KDM3A,FAM189A1,CBX5,JMJD1C,MSRB3,FXR1,GAN" MicroRNA hsa-miR-4698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-18 1.91E-14 7.58E-18 6.97E-17 41 216 "XKR4,SPOP,ZMYM4,EVI5L,PLAA,TOGARAM2,CENPL,SPATA2,EDIL3,FEM1B,EIF5,TENM1,DCTN4,MRPL37,MED12L,CELF1,RAPGEF6,FUT10,HAS2,ZNF181,KPNA5,CHST6,GPR137C,CCSER2,ZNF426,RFX3,KLHL11,SETD5,FBXW7,BDP1,SOX11,PEG10,ZC3H13,NECAB1,SYPL1,SLC19A3,ZMAT3,TLR4,TBC1D15,ZNF708,ZXDA" MicroRNA "GGTGTGT,MIR-329:MSigDB" "GGTGTGT,MIR-329:MSigDB" MSigDB 3.57E-18 2.00E-14 7.93E-18 7.30E-17 29 103 "BCL7A,PTBP2,KRIT1,CLTB,CRMP1,CSNK1G3,DAPK1,SUGP2,EIF4G1,RNF165,IL6ST,MEF2C,RTL5,MYT1,PDE4D,ZNF655,PRKACB,ZFHX4,FAM219A,NFASC,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CLDND1,NAV3" MicroRNA hsa-miR-6760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.57E-18 2.00E-14 7.93E-18 7.30E-17 42 227 "ELFN2,PPFIA3,SEMA4G,HAP1,ARHGEF6,RGS6,TM9SF4,IP6K1,ELMSAN1,CHRDL1,FGFR1,ANKFY1,GLYR1,IDH3A,SLC6A17,SAMD14,NBL1,ZC3H12B,PDE4A,GPR173,KCTD15,NKAIN1,MORC4,RNH1,CCDC88A,SLC11A1,SP2,ERC1,NEK4,ADAMTS17,ASTN2,FBXW11,ZNF34,TPM2,WBP2,TUBB2A,ZIC2,ZNF70,GDPD5,SIGLEC10,ACTR3B,FAM198A" MicroRNA hsa-miR-6873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.77E-18 2.11E-14 8.35E-18 7.69E-17 40 206 "RNF157,AK2,MTMR3,DDR1,CALM1,HAP1,ARHGEF6,ENTPD4,PITPNM3,IST1,IP6K1,CHRDL1,MAMLD1,EIF4G1,HSPA12B,GLYR1,TDRKH,SHISAL1,NKD1,SLC6A17,SAMD14,ZC3H12B,NPTX1,ZNF827,KCTD15,MTRF1L,NKAIN1,PRRT2,MYO18A,CCDC88A,SLC11A1,SP2,ERC1,IQSEC2,ADAMTS17,WBP2,VSNL1,ZIC2,ZNF70,SIGLEC10" MicroRNA hsa-miR-1910-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-18 2.20E-14 8.73E-18 8.03E-17 64 501 "ABCF1,XKR4,ELFN2,HECW2,TRMT9B,SHROOM2,ARHGDIA,DNAH17,DDR1,ISPD,CBFA2T2,NRXN3,AKAP5,UBXN2A,TMEM170A,DNAL1,EBI3,RASA4,MRNIP,MTSS1L,IGSF6,ANKMY1,KATNAL1,ZNF589,VTI1B,TRMO,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,FERMT2,KAT7,DDX19B,ZNF546,RBPJ,IBA57,COMMD5,NBL1,CNOT4,CCSER2,PLXNB1,RETREG2,POLR2F,QDPR,ZNF793,CPEB3,MYO18A,ATF7IP,ZSCAN29,NEK4,SLC37A2,FAM208A,SATB2,NACC2,PPIL6,ZNF708,ZNF70,AMZ1,DPYSL5,EVI5" MicroRNA hsa-miR-6747-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-18 2.20E-14 8.73E-18 8.03E-17 64 501 "AS3MT,RNF157,ADD1,RNF150,ESYT2,TAOK1,ABCD2,CDC14B,ARSE,SLC4A4,CACNA1A,STOML1,QKI,RTTN,CREM,HINFP,CSNK1E,PITPNM3,KIAA0408,DNAL1,CNNM1,MRNIP,RGS17,SLC43A2,TLR7,FKTN,FDFT1,FOXO3,PDLIM5,CRCP,RAB40B,PTPRT,RNF165,ZDHHC15,EID2B,IL6R,NCOA7,LSAMP,CHST6,ALDH1L2,MTRF1L,APTX,TMEM231,ZNF844,NWD1,GTDC1,DCUN1D2,PGBD4,RXRA,SCN2B,ZFP30,PEX26,ZNF667,ARHGAP26,AGTPBP1,GPRIN3,ZNF106,ARL10,ERCC6L2,PARD3,RPL7L1,AGMO,ZNF70,MPPE1" MicroRNA hsa-miR-3913-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-18 2.23E-14 8.84E-18 8.14E-17 54 369 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,PLEKHA1,MRNIP,IGSF6,ANKFY1,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,IRAK3,IGF1,STMN1,MATN3,PPM1L,SLC11A2,OCRL,ZNF713,RETREG2,CNTLN,MTMR10,CEP97,FBXW7,GALNT10,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20,GAN" MicroRNA hsa-miR-6875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-18 2.25E-14 8.91E-18 8.20E-17 45 261 "RALGAPA1,FMNL2,SPOP,TNRC6C,ARSE,CDK13,NUMBL,BAG4,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,STARD3NL,COQ7,DLC1,GORAB,PCDH17,HAS2,NCKAP1L,NEGR1,SHISA6,SYTL4,LSAMP,SRSF12,NOVA2,FAM98B,PLCL1,PNMA3,PRKCB,SH3TC2,TMLHE,TRAPPC13,CSRNP3,SSTR2,MPRIP,DIP2A,ADAMTS17,TBL1X,ASXL3,RPL7L1,UGT8,JMJD1C,ZDHHC20" MicroRNA hsa-miR-551a:mirSVR_lowEffct hsa-miR-551a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.02E-18 2.25E-14 8.91E-18 8.20E-17 47 284 "KDM5D,DPP10,CACNA1B,RUNX1T1,P2RX6,ZBED1,PPT2,COL4A5,APPL1,CENPL,MFAP3L,MAMLD1,HIPK3,GOLGA7,VPS13B,ERBB2,ERBB4,ANKMY1,ZSCAN30,FGFR1,POMT1,DISC1,ADAM28,LNX1,SYNPO,IRF8,SFXN5,MBP,MEIS1,OGG1,PDE4B,ING3,PPP2R2B,GTDC1,ABCA11P,KCNIP3,FAM81A,SNRPN,KDM4B,ZC3H13,ARHGEF9,COBL,SYNE1,RNF103,EPM2A,FBXO36,KLHDC1" MicroRNA "CCCAGAG,MIR-326:MSigDB" "CCCAGAG,MIR-326:MSigDB" MSigDB 4.09E-18 2.29E-14 9.04E-18 8.32E-17 34 147 "RALGAPA1,OGT,ATP2B2,DLGAP2,WHRN,CSNK1G3,RIMS4,NCALD,CORO2B,ANKFY1,GGT7,HPGDS,GNAO1,DIDO1,ADAMTS6,LRRTM1,PALM,KCTD15,PURG,PKIA,DUSP15,SEMA6D,PPM1E,FNDC3A,BTBD3,EPN2,INAVA,FAIM2,TCF4,CDH22,VLDLR,NAV3,PPP1R3F,ST8SIA2" MicroRNA hsa-miR-200b-3p:Functional MTI Functional MTI miRTarbase 4.21E-18 2.36E-14 9.32E-18 8.58E-17 38 186 "TXNDC16,CDC14B,ARHGDIA,STX16,SEPT7,QKI,BAG4,PHF14,RASSF2,MATR3,MAMLD1,DNAJB6,ACSL4,DLC1,FLT1,CELF1,SESN1,MALT1,FERMT2,RASSF8,TJAP1,PDPK1,PKD1,MAPK7,PTPRD,OXR1,ZFHX4,WDR37,ELMO2,MBD5,KIF13A,ZNF621,ERBIN,ZEB1,ZFPM2,ZMAT3,TUBB2A,HNRNPA3" MicroRNA hsa-miR-525-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.26E-18 2.38E-14 9.42E-18 8.67E-17 33 138 "PCDH19,TAOK1,SEMA7A,APBB2,ZNF582,CDC25B,NRXN3,C2CD2L,RASGRP1,REEP2,FOXO3,AFF2,CELF1,ZNF274,MPP2,ZNF827,ZNF426,PPP2R5E,PRKCB,SETD5,ELP2,RXRA,NCBP3,HES6,SGK1,PEX26,ATF7IP,ARHGAP26,TACC1,AGMO,CIAPIN1,URM1,NELFE" MicroRNA hsa-miR-3122:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-18 2.52E-14 9.97E-18 9.18E-17 54 370 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,PLEKHA1,MRNIP,IGSF6,ANKFY1,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,IRAK3,IGF1,STMN1,MATN3,PPM1L,SLC11A2,OCRL,ZNF713,RETREG2,CNTLN,MTMR10,CEP97,FBXW7,GALNT10,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ERCC6L2,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20,GAN" MicroRNA hsa-miR-197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.78E-18 2.68E-14 1.06E-17 9.72E-17 57 409 "TAOK1,TRMT9B,CDK10,ARSE,ATP1A1,ATP2A2,FOXN3,CPNE6,RAB28,AKAP6,CSNK1E,GAPVD1,KIAA0586,MAML1,DBT,SPATA2,DPH1,WDPCP,HIPK3,PIPOX,DLC1,FOXO3,TRMO,MPP6,ZNF274,SRCAP,GGT7,KIAA1958,PTPRT,GSTM5,RNFT2,DDX19B,IDH3B,KPNA5,MSI1,MYO6,MINDY2,ZNF793,C12orf49,SNX22,FBXW7,SH3BP2,NUBPL,PDZRN3,SOX11,SPART,ZNF302,SS18,NEK4,ALG1,AGTPBP1,CYB561A3,CBX5,ZNF708,ZNF70,MSRB3,GAN" MicroRNA "CAGCAGG,MIR-370:MSigDB" "CAGCAGG,MIR-370:MSigDB" MSigDB 5.12E-18 2.87E-14 1.13E-17 1.04E-16 34 148 "ABR,XKR4,MTUS1,TAOK1,PCDH10,OGT,USP37,CASK,CHRD,SLC4A4,JAZF1,USP6,SRSF11,HDAC4,GRIN3A,YAF2,PHF20L1,NCALD,PSD2,GABBR1,CIT,ZC3H12B,ING3,PPM1B,VSTM2L,RAP1GDS1,RGS3,PBRM1,STX1B,PKNOX2,IQSEC2,NFASC,KLC2,PRDM10" MicroRNA hsa-miR-125b:mirSVR_highEffct hsa-miR-125b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.17E-18 2.90E-14 1.14E-17 1.05E-16 59 436 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,ARNTL,CDK13,USP2,P2RX6,SULT4A1,LY86,SLC4A8,HINFP,KIAA0586,IST1,SPEG,SEMA4D,CGREF1,KIAA1841,RAB30,RABL2A,AGBL5,MSL1,ZNF546,KCNN2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,TMLHE,ATP8B4,COPZ1,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,DIP2A,C18orf54,MTMR14,TLR4,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,SEMA3B,EPM2A,TIGD6,IFT88" MicroRNA hsa-miR-4290:mirSVR_highEffct hsa-miR-4290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.26E-18 2.94E-14 1.16E-17 1.07E-16 55 384 "VWA5B2,PTCHD1,BCAS1,NUMB,CFLAR,C5,CAMK2G,CERS5,CD86,LOC730101,LARGE1,PICK1,PHACTR3,KIAA0586,IP6K1,KIAA0319,DDX46,NYAP1,PHF20L1,EGR3,PLEKHA1,ADGRV1,NSRP1,FER,MEGF10,SESN1,COPS8,STMN2,AP4S1,SYNPO,IDH3B,LRP1B,MEF2C,MYO9A,CNTN3,ZNF655,TMEM260,NKAIN1,ACSS3,ZCWPW1,RPE,NEK11,SCN8A,ASAP3,USP33,KDM4C,ZNF423,SEPT3,VPS13A,PLCB1,TACC1,CAMTA1,ZEB1,TPM2,JPH3" MicroRNA hsa-miR-6829-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.53E-18 3.09E-14 1.22E-17 1.12E-16 50 322 "MTA3,SLC4A4,GYG2,CACNA1A,IGLON5,RTTN,KIAA0408,TMEM170A,ZBTB24,C2CD2L,TMCC2,KRBA2,CNNM1,RGS17,TUBD1,REEP2,FKTN,PDLIM5,MSANTD4,GGT7,RAB40B,DDX19B,ZDHHC15,NKD1,METTL21A,LIMS1,GPR155,MTRF1L,EXOSC10,FITM2,APTX,PIGG,ZSCAN2,PRRT2,MRPS18A,KLHL11,GALNT10,PEX26,PKNOX2,SLC6A8,FAIM2,AGTPBP1,PCDHA6,ZNF106,ARL10,ERCC6L2,PARD3,SSBP2,AGMO,GAN" MicroRNA hsa-miR-6791-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.53E-18 3.09E-14 1.22E-17 1.12E-16 50 322 "MTA3,SLC4A4,GYG2,CACNA1A,IGLON5,RTTN,KIAA0408,TMEM170A,ZBTB24,C2CD2L,TMCC2,KRBA2,CNNM1,RGS17,TUBD1,REEP2,FKTN,PDLIM5,MSANTD4,GGT7,RAB40B,DDX19B,ZDHHC15,NKD1,METTL21A,LIMS1,GPR155,MTRF1L,EXOSC10,FITM2,APTX,PIGG,ZSCAN2,PRRT2,MRPS18A,KLHL11,GALNT10,PEX26,PKNOX2,SLC6A8,FAIM2,AGTPBP1,PCDHA6,ZNF106,ARL10,ERCC6L2,PARD3,SSBP2,AGMO,GAN" MicroRNA hsa-miR-508-5p:Functional MTI Functional MTI miRTarbase 5.56E-18 3.11E-14 1.23E-17 1.13E-16 62 477 "XKR4,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,ARSE,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,C2CD2L,KLHL3,MTX3,FSD1L,EBI3,EPB41,ANKFY1,TRMO,ZNF234,CRCP,GPR75,FICD,DDX19B,AGBL5,KCNN3,CHST6,ZC3H12B,SLC11A2,PAX6,ABCB1,CCSER2,MTRF1L,PSAT1,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ALG9,ATAT1,ZNF331,HES6,SEPHS1,FNBP1,MCF2L2,ARL10,PPIL6,SSBP2,ZNF610,UBC,USP1,TBC1D15,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-375:TargetScan hsa-miR-375 TargetScan 5.73E-18 3.21E-14 1.26E-17 1.16E-16 41 219 "EIF4G3,DPY19L3,DST,LDLRAD4,CAST,KCNAB3,QKI,PLXNA4,MATR3,KLHL3,EIF1,EPB41L2,PIPOX,NBEA,GALNT15,C15orf41,RASSF8,HAS2,BACH2,MIER3,RBPJ,INSM1,JAK2,MBNL1,MEIS1,MSI1,MXI1,MYO9A,NFIX,PAX6,PDE3A,PDE4D,PDPK1,CEP41,ANKHD1,GTDC1,RORB,AP1AR,ATXN7,SCN2B,ERC1" MicroRNA hsa-miR-455-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.83E-18 3.26E-14 1.28E-17 1.18E-16 83 784 "ABCF1,NDRG3,SLC24A4,HECW2,HACE1,ZNF578,USP37,AQP6,CDC14B,ASPA,STX16,ZNF583,DOCK11,BACH1,BCL7A,PTBP2,CBS,CBFA2T2,CDR1,CCPG1,NRXN3,PLAA,TPP1,PLCXD3,MYADM,GAPVD1,TMEM170A,DNAL1,GUCD1,MTX3,DNAH9,MRO,RASA4,EIF4G1,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,BAIAP2,TRMO,MTHFD2,DISC1,KIAA1841,CRCP,GLUL,GNG4,LILRA2,MIER3,IGF1,IBA57,MPP2,MXI1,CCSER2,TATDN3,NDUFS7,NCR3LG1,MTMR10,CEP97,ZNF793,RBBP8,ALG9,PTGR2,NCBP3,FNIP1,SHC4,ATF7IP,FNBP1,LHPP,MGRN1,ZEB1,USP22,BHLHB9,WBP2,PPIL6,SSBP2,USP1,LAT2,EVI5,JPH3" MicroRNA hsa-miR-876-5p:PITA hsa-miR-876-5p:PITA_TOP PITA 5.85E-18 3.27E-14 1.29E-17 1.19E-16 39 198 "ASIC1,XKR4,AXIN2,PCDH19,TAOK1,SEMA6A,OGT,DPP10,PPFIA3,RNF182,MTMR3,JAZF1,QKI,SNCAIP,GAPVD1,DBN1,MTX3,RCAN1,NRN1,CAMKK2,ARFIP1,SESN1,NEGR1,KCNN3,KIFC3,MAT2A,MBNL1,MEF2C,MN1,CLDN11,PMP22,PTPRD,CEP97,TMCC1,SS18,CUX2,FAM155A,REEP1,SOCS4" MicroRNA hsa-miR-425*:mirSVR_highEffct hsa-miR-425*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.17E-18 3.45E-14 1.36E-17 1.25E-16 38 188 "ADRB2,LRCH2,EPB41L5,LINC00173,TTLL9,BTK,EPS15L1,ARMC8,COL9A1,SEC31B,CLIP3,UBXN2A,DOCK4,HS3ST2,DTNA,ANKRD46,KLHL5,GPHN,FDFT1,IGSF5,CBX1,GABARAPL2,KCND1,MYO9A,NUCB2,PCSK1,PFKFB4,SMIM7,SCHIP1,MTMR10,FAM192A,NUBPL,MAST1,SEPT8,TACR1,ZNF138,TRAM2-AS1,NETO1" MicroRNA hsa-miR-10b-5p:Functional MTI Functional MTI miRTarbase 6.31E-18 3.53E-14 1.39E-17 1.28E-16 50 323 "ADRA1B,SLC24A4,TXNDC16,C6orf89,STK33,NRP2,USP6,ZNF445,CRY2,NCOR2,IPCEF1,USP6NL,CENPL,TMEM170A,MTX3,DLX1,USP3,AASDH,FEM1B,FAM13A,MBNL2,EIF1,TUBA1B,MSL3,LILRA2,PTPRT,SYNPO,LSS,MBNL1,NF1,NPTX1,SLC11A2,PAX6,PPARA,DPF2,KLHDC8A,NCBP3,CSRNP3,TRA2B,KIF21A,PRRC2C,FAM208A,ZEB1,TRIM2,TIAM1,CSMD1,TPM1,NR2C2,RUNDC3B,ZNF708" MicroRNA hsa-miR-6749-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.50E-18 4.20E-14 1.65E-17 1.52E-16 55 387 "ADD1,RNF150,SEMA4G,PRX,CASTOR3,CA8,CAMK2G,STOML1,RTTN,LRIG1,UBXN2A,PLCXD3,RIPOR2,KIF26A,RUSC2,KIAA0319,TMCC2,EXOG,RCAN1,TMTC1,SLC43A2,TMEM132C,FER,IP6K2,UFM1,GABRG2,POLL,ADAMTS13,FAM107A,BACH2,SHISA6,NKD1,LSAMP,MAT2A,MID1,MYO5A,PKD1,PNMA3,NCR3LG1,GSTCD,HSD11B1L,ZHX3,NSFL1C,EXOC7,NSD1,ZMAT3,THRA,NACC2,GORASP1,TMEM198,SLC30A3,SIGLEC10,FAM13C,GAN,JPH3" MicroRNA hsa-miR-519a-3p:Functional MTI Functional MTI miRTarbase 7.51E-18 4.20E-14 1.65E-17 1.52E-16 52 349 "TAOK1,SEMA7A,CFL2,EPS15L1,CLCN3,QKI,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,CERCAM,C3orf18,KATNAL1,ACSL4,FKTN,POLR1B,SEC23B,FOXF2,CELF1,GRB10,FICD,KCNB1,MBNL1,NBL1,CNOT4,CEP97,RBBP6,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,ATMIN,SATB2,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-452-5p:TargetScan hsa-miR-452-5p TargetScan 8.12E-18 4.54E-14 1.78E-17 1.64E-16 43 243 "ELFN2,GALNT13,RNF157,ANK2,FUBP1,CACNA2D1,CAMK2G,DCLK1,CACNA2D2,CHN1,FHL5,MATR3,GRIN3A,ERBB4,AMOTL2,HPCAL4,MSANTD4,PCDH17,RAB30,PACSIN2,AGFG1,IGF1,IL6ST,KCNB1,KCNN3,KIT,NCOA7,MEF2C,P2RY1,PDE4D,GPR173,POU6F1,ROBO2,FBXO11,ANKRD28,MGRN1,RGMB,FLRT2,ANKS1B,EVI5,NAV3,RGS7BP,MSRB3" MicroRNA hsa-miR-892c-3p:TargetScan hsa-miR-892c-3p TargetScan 8.12E-18 4.54E-14 1.78E-17 1.64E-16 43 243 "ELFN2,GALNT13,RNF157,ANK2,FUBP1,CACNA2D1,CAMK2G,DCLK1,CACNA2D2,CHN1,FHL5,MATR3,GRIN3A,ERBB4,AMOTL2,HPCAL4,MSANTD4,PCDH17,RAB30,PACSIN2,AGFG1,IGF1,IL6ST,KCNB1,KCNN3,KIT,NCOA7,MEF2C,P2RY1,PDE4D,GPR173,POU6F1,ROBO2,FBXO11,ANKRD28,MGRN1,RGMB,FLRT2,ANKS1B,EVI5,NAV3,RGS7BP,MSRB3" MicroRNA "GTGCAAT,MIR-25:MSigDB" "GTGCAAT,MIR-25:MSigDB" MSigDB 8.24E-18 4.61E-14 1.81E-17 1.66E-16 47 289 "FAM135A,OGT,DPP10,ATP2A2,HCN2,SYNJ1,CACNA1I,KALRN,DLGAP2,TMEM184B,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,IQGAP2,GLYR1,PIK3AP1,MARK1,P2RY13,NFIX,NOVA1,NPTX1,CEP41,PTPRO,REV3L,RGS3,ROBO2,FBXW7,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,TRIO,TSC1,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-367:MSigDB" "GTGCAAT,MIR-367:MSigDB" MSigDB 8.24E-18 4.61E-14 1.81E-17 1.66E-16 47 289 "FAM135A,OGT,DPP10,ATP2A2,HCN2,SYNJ1,CACNA1I,KALRN,DLGAP2,TMEM184B,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,IQGAP2,GLYR1,PIK3AP1,MARK1,P2RY13,NFIX,NOVA1,NPTX1,CEP41,PTPRO,REV3L,RGS3,ROBO2,FBXW7,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,TRIO,TSC1,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-32:MSigDB" "GTGCAAT,MIR-32:MSigDB" MSigDB 8.24E-18 4.61E-14 1.81E-17 1.66E-16 47 289 "FAM135A,OGT,DPP10,ATP2A2,HCN2,SYNJ1,CACNA1I,KALRN,DLGAP2,TMEM184B,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,IQGAP2,GLYR1,PIK3AP1,MARK1,P2RY13,NFIX,NOVA1,NPTX1,CEP41,PTPRO,REV3L,RGS3,ROBO2,FBXW7,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,TRIO,TSC1,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-363:MSigDB" "GTGCAAT,MIR-363:MSigDB" MSigDB 8.24E-18 4.61E-14 1.81E-17 1.66E-16 47 289 "FAM135A,OGT,DPP10,ATP2A2,HCN2,SYNJ1,CACNA1I,KALRN,DLGAP2,TMEM184B,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,IQGAP2,GLYR1,PIK3AP1,MARK1,P2RY13,NFIX,NOVA1,NPTX1,CEP41,PTPRO,REV3L,RGS3,ROBO2,FBXW7,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,TRIO,TSC1,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-92:MSigDB" "GTGCAAT,MIR-92:MSigDB" MSigDB 8.24E-18 4.61E-14 1.81E-17 1.66E-16 47 289 "FAM135A,OGT,DPP10,ATP2A2,HCN2,SYNJ1,CACNA1I,KALRN,DLGAP2,TMEM184B,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,IQGAP2,GLYR1,PIK3AP1,MARK1,P2RY13,NFIX,NOVA1,NPTX1,CEP41,PTPRO,REV3L,RGS3,ROBO2,FBXW7,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,TRIO,TSC1,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-9-5p:Functional MTI Functional MTI miRTarbase 8.52E-18 4.77E-14 1.87E-17 1.72E-16 52 350 "TAOK1,ALCAM,APBB2,KIF1A,CA8,SPAG9,PLEKHB1,SUMF2,TBPL1,NCOR2,ARHGEF10,SOCS5,HDAC4,MTX3,OPTN,FOXO3,ANKFY1,NBEA,ZBED3,CAMKK2,MTHFD2,RASSF8,LRRTM1,STMN1,MN1,MSR1,NF1,NTRK3,PRTG,PPARA,PTX3,ZMAT4,PCMTD2,ATXN7,FERMT1,SLC2A5,CPEB4,FNBP1,NMNAT2,POGZ,STAU1,SYNE2,SYPL1,TAL1,SYNE1,SLC19A3,DICER1,SIRT1,ITGB3BP,NR2E1,SLC30A4,RNF146" MicroRNA hsa-miR-520a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.59E-18 4.80E-14 1.88E-17 1.73E-16 33 141 "PCDH19,TAOK1,SEMA7A,APBB2,ZNF582,CDC25B,NRXN3,C2CD2L,RASGRP1,REEP2,FOXO3,AFF2,CELF1,ZNF274,MPP2,ZNF827,ZNF426,PPP2R5E,PRKCB,SETD5,ELP2,RXRA,NCBP3,HES6,SGK1,PEX26,ATF7IP,ARHGAP26,TACC1,AGMO,CIAPIN1,URM1,NELFE" MicroRNA hsa-miR-432:PITA hsa-miR-432:PITA_TOP PITA 8.83E-18 4.94E-14 1.93E-17 1.78E-16 35 160 "UNC5A,PWWP2A,PTCHD1,EIF4G3,FOXN3,NRXN3,SLC35F1,SOCS5,ARHGEF4,PITPNC1,ALKBH8,RHOBTB1,CPEB2,DNAJB6,OPTN,GOLGA7,EPB41,ERBB4,GHR,TCERG1,PCLO,GRIA2,FAM222A,CHIC1,PDE1B,PMP22,STRN3,TMEM260,RASGRF1,FBXW7,SCP2,CCDC88A,FAM126B,RBM26,SYN1" MicroRNA hsa-miR-943:PITA hsa-miR-943:PITA_TOP PITA 8.83E-18 4.94E-14 1.93E-17 1.78E-16 35 160 "AMPH,NUMB,JAZF1,CALM1,IQCK,CSNK1G3,ARHGEF4,ARMCX2,CPEB2,HPCAL4,MSTN,RNPS1,TDRKH,SPACA9,ELOVL5,NEGR1,ZIC5,STXBP5,MBNL1,MBP,MYCN,NOVA1,NRCAM,PDPK1,ENOX1,RDX,RPL15,CPEB3,BTBD7,FAM219A,KDM4C,TRIM9,SLC38A1,HNRNPA3,FRMD6" MicroRNA hsa-miR-324-3p:Functional MTI Functional MTI miRTarbase 9.00E-18 5.04E-14 1.97E-17 1.81E-16 51 338 "AP2A1,PITPNM2,LRFN1,STX16,SYNJ2,FUBP1,CACNA1I,MAGI1,TOGARAM2,CPS1,APPL1,PUM1,YTHDC1,ARRDC4,EBI3,MRPL37,NSRP1,RACK1,SEC24B,SEC23B,KIAA1841,SRCAP,KDM2B,PRRC2B,FAM107A,ATXN2L,ACOT7,MAP4,MAT2A,MBD1,MYO6,ZDHHC8,PKM,PIGG,KLHL11,SBF1,FOXRED1,HSPA4L,CDK5RAP2,ARHGAP26,RBM26,POGZ,MPRIP,STAC2,SUPT5H,PRRC2C,KIAA0930,NACC2,UBC,ZNF23,UBE3B" MicroRNA hsa-miR-299-5p:PITA hsa-miR-299-5p:PITA_TOP PITA 9.26E-18 5.18E-14 2.03E-17 1.87E-16 36 170 "ABR,KLHL13,ALCAM,STX16,FOXN3,SULT4A1,CS,SOCS5,HDAC4,LONRF1,CPEB2,HIPK3,ELN,MEGF10,IQGAP2,AHDC1,GFRA2,DHX35,ZIC5,MAT2A,KITLG,PCDH8,PFKFB2,NLGN3,ROBO1,SGK1,CHD9,CCDC88A,SOX11,CLSTN2,POGZ,PLCB1,PUM2,NR2C2,NAV3,KCNAB1" MicroRNA hsa-miR-1226:PITA hsa-miR-1226:PITA_TOP PITA 9.30E-18 5.21E-14 2.03E-17 1.87E-16 37 180 "KCNH8,OGT,BCL7A,HAP1,CAMK2G,MAP4K4,AATK,LRIG1,OSBPL3,ALKBH8,DPH1,ELN,DCTN4,ERBB4,AFF2,SYT3,LOXL3,MCHR1,ACOT7,SLC6A17,MAT2A,MBD1,NPTX1,TMEM255A,CYB561D1,ROBO1,FBXW7,CASC3,FAM102A,FBXO11,CPEB4,SOX11,LMO3,ERBIN,SEPT3,PRRC2C,THRA" MicroRNA hsa-miR-5095:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.52E-18 5.33E-14 2.08E-17 1.92E-16 56 402 "CLK4,ESYT2,TAOK1,ATP1B3,SLC2A11,LDHD,ZMYM4,DIS3L,PLAA,LETMD1,RNF14,SOCS5,SLC12A6,EIF4G2,IRAK4,MRNIP,TUBD1,SLC43A2,TUBA1B,CEP78,FDFT1,GTF2IRD2,ZNF44,TRAF3IP2,TXNL4A,RNPS1,ZNF491,NKD1,IL6R,SLC6A17,METTL21A,CYP27C1,LAMP2,MAT2A,MBD1,CHST6,ZNF426,MINDY2,SETD5,C12orf49,HSPA4L,SGK1,FAM126B,SP2,ZNF621,PBLD,DIP2A,ZMAT3,CBX5,PARD3,RPL7L1,CFAP298,ZNF70,SIGLEC10,MPPE1,AP3B2" MicroRNA hsa-miR-6077:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-17 5.91E-14 2.31E-17 2.12E-16 46 279 "RNF157,PHF12,ARRB2,LDHD,TMEM184B,CRY2,CNTNAP2,IST1,SNX29,C8orf37,MTSS1L,ENPP6,AMOTL2,BRSK1,CRCP,GLYR1,TNRC6A,PRRC2B,GRIN2D,FICD,LINGO1,MIER3,NKD1,ZIC5,RBPJ,TJAP1,SLC35G1,SLC25A23,MINDY2,FIGN,COA1,MYH15,ANKRD36,UNC5B,ZC3H4,ASTN2,NSD1,HIF3A,ZNF106,NACC2,TLR4,WRN,ZXDA,DNALI1,FXR1,GAN" MicroRNA hsa-miR-4278:mirSVR_highEffct hsa-miR-4278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-17 6.13E-14 2.39E-17 2.20E-16 49 315 "ABCF1,GALNT16,WDR35,CHID1,SLC2A11,ALDH7A1,C5,CAPN3,DGKI,DCLK1,SRSF11,CHN1,TRIM69,KATNAL2,DCAF8,ELMSAN1,PHF20L1,TNK2,EPHB1,AGAP3,ABLIM2,TRAF3IP2,TTBK1,DBF4,ATP2B1-AS1,RBPJ,MXI1,STRN3,EPB41L4B,RANBP3L,VPS13C,TCP11L1,CSRNP3,FBXO11,INAVA,DOP1A,LMO3,RGL1,SUPT5H,SYNE2,ITGB3BP,ELP5,STXBP4,VSNL1,KCNT2,MKRN3,PCBP4,LAS1L,JPH3" MicroRNA hsa-miR-376a-3p:TargetScan hsa-miR-376a-3p TargetScan 1.21E-17 6.75E-14 2.63E-17 2.42E-16 39 202 "BEND6,ABCD2,PITPNM2,ANK2,BAG4,FAM131B,CCDC144A,PYGO1,HDAC9,IP6K1,JAKMIP2,GRIN3A,FGFR1,POLK,KHDRBS3,PCDH17,FERMT2,HAS2,METTL21A,LAYN,PAX6,PIK3R1,LRP12,EXOSC10,PRKACB,GAL3ST4,ARMC5,HUNK,SATB1,CHD9,FBXO11,MBD5,FAM126B,CDK19,CLASP2,CUX2,CABIN1,ELP5,PPP1R3F" MicroRNA hsa-miR-376b-3p:TargetScan hsa-miR-376b-3p TargetScan 1.21E-17 6.75E-14 2.63E-17 2.42E-16 39 202 "BEND6,ABCD2,PITPNM2,ANK2,BAG4,FAM131B,CCDC144A,PYGO1,HDAC9,IP6K1,JAKMIP2,GRIN3A,FGFR1,POLK,KHDRBS3,PCDH17,FERMT2,HAS2,METTL21A,LAYN,PAX6,PIK3R1,LRP12,EXOSC10,PRKACB,GAL3ST4,ARMC5,HUNK,SATB1,CHD9,FBXO11,MBD5,FAM126B,CDK19,CLASP2,CUX2,CABIN1,ELP5,PPP1R3F" MicroRNA hsa-miR-377-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-17 6.84E-14 2.66E-17 2.45E-16 68 569 "ABCF1,NDRG3,SLC24A4,HECW2,HACE1,ZNF578,TRMT9B,AQP6,CDC14B,EIF4G3,DOCK11,PTBP2,CBS,CBFA2T2,ARHGEF2,CDR1,CCPG1,NRXN3,ZNF385A,USP6NL,GAPVD1,TBC1D5,DNAL1,DBT,MTX3,DNAH9,MRO,RASA4,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,FAM198B,ZNF585B,SCML2,FECH,DISC1,CRCP,GNG4,LILRA2,KAT7,IGF1,TJAP1,IBA57,MXI1,PPP3CC,NCR3LG1,CEP97,RBBP8,ALG9,GSTCD,PTGR2,NCBP3,FNIP1,ATF7IP,CPEB4,FNBP1,CDK19,FAM208A,TPCN2,DICER1,BHLHB9,LAT2,CLDND1,ZNF17,ZNF70,EVI5" MicroRNA hsa-miR-572:mirSVR_lowEffct hsa-miR-572:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-17 6.92E-14 2.70E-17 2.48E-16 52 353 "UNC5A,CC2D2A,PITPNM2,FGD2,CARMIL3,USP6,CD38,MAP4K4,SUMF2,LETMD1,CTH,RUBCN,CYBB,DGKG,DMPK,TOM1,GOLGA7,ELN,ENO2,EPHB1,STX2,TUBB3,GORAB,SUCO,STARD3,MUM1,LRRCC1,MAPT,MBD1,DNHD1,ING3,POLR2F,NDUFS7,PIGG,PTPRN2,RORB,ATAT1,KIF16B,ABLIM3,CDK5RAP3,MYO16,BDP1,EXOC7,TPCN2,PCDHA5,CDH22,TIAM1,TPM1,FAM155A,URM1,FIP1L1,PCBP4" MicroRNA hsa-miR-6832-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-17 7.01E-14 2.73E-17 2.51E-16 49 316 "ADCY5,MTA3,AK2,USP37,SEMA4G,ARSE,BID,MYRF,CBS,ZNF445,SRSF11,SEC31B,IPCEF1,PLCXD3,ELMSAN1,CHRDL1,PHF20L1,STARD3NL,SLC43A2,FOXO3,ANKFY1,GALC,SRCAP,SULT1C4,KCNMB4,TPPP,PTPRT,DDX19B,BACH2,MIER3,KCNB1,LSAMP,MBNL1,XRRA1,SAMD5,NPTX1,OLA1,PPP3CC,ZSCAN2,MARCH1,CEP97,GTDC1,ELP2,ATXN7,GALNT10,MYO18A,SLC38A1,SIGLEC10,WNK3" MicroRNA hsa-miR-193a-3p:PITA hsa-miR-193a-3p:PITA_TOP PITA 1.36E-17 7.58E-14 2.95E-17 2.72E-16 33 143 "KCNH8,UPRT,STX16,CALB1,CALM1,RUNX1T1,FAM131B,ZC3H11A,ETV1,FGF1,ANKFY1,ST6GALNAC3,GNAO1,KIT,CAMK2N2,STMN1,MYCN,NEXMIF,NOVA1,CCSER2,MSANTD2,ZHX3,HECW1,ERBIN,ST5,CAMTA1,AGTPBP1,TCF4,DMXL2,LRRC8A,R3HDM1,NAV3,RNF146" MicroRNA hsa-miR-758-3p:TargetScan hsa-miR-758-3p TargetScan 1.37E-17 7.65E-14 2.98E-17 2.74E-16 37 182 "C3orf14,ADD1,RNF150,MAP4K3,CDK13,ATP2B2,BMP7,LURAP1,CFL2,HIPK3,FAM13A,ENPP6,GPR37,RASSF8,DDX19B,ARHGAP36,BACH2,HLF,IL6ST,MEIS2,MMP16,PAX6,PLCL1,PPP2R2C,PKIA,RELN,GTDC1,GALNT10,HSPA4L,CPEB4,ERC1,CDK19,ADAMTS17,CUX2,PUM2,CBX5,RBFOX3" MicroRNA hsa-miR-450b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-17 8.07E-14 3.14E-17 2.89E-16 39 203 "KCTD16,SEMA6A,GAS7,BACH1,BCL7A,BID,CALM1,SCARB1,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,SPATA2,TIAM2,GUCD1,EDN1,STARD3NL,EPHB1,SLC43A2,ACSL4,SCML2,FER,PRRC2B,RBPJ,LIMS1,OCRL,P2RY1,PLIN1,STRN3,ACSS3,NWD1,KCNIP3,SATB1,PEX26,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-101-3p:Functional MTI Functional MTI miRTarbase 1.51E-17 8.43E-14 3.28E-17 3.02E-16 55 393 "TRMT9B,LRCH2,STX16,CBFA2T2,C1orf52,CPS1,SPATA2,ZC3H11A,RAB39B,MBNL2,GOLGA7,EIF4G2,PLEKHA1,MTSS1L,EYA1,ANKFY1,STAMBP,DIDO1,DDX19B,ZDHHC15,FAM69A,JAK2,KLHL23,STMN1,LIFR,MBNL1,MEIS1,MITF,MKLN1,MYCN,MYO9A,NACA,SLC11A2,CHAMP1,ZNF827,PPP2R5E,QDPR,PGBD4,FBXW7,RMI1,FBXO11,FNDC3A,TRERF1,ITPRID2,NXT2,ZEB1,DICER1,TSN,RPL7L1,WNT7A,SPIRE1,MPPE1,RTN4,FRMD6,GAN" MicroRNA hsa-miR-3202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-17 8.68E-14 3.37E-17 3.11E-16 45 270 "ELFN2,HECW2,TAOK1,SEMA4G,ARRB2,DPY19L3,RUNX1T1,CBFA2T2,ZNF385A,DCAF4,FAM131B,IP6K1,SPATA2,APH1A,MRO,GCK,PRRC2B,ZNF496,NXPH3,TNFAIP8L3,ZFYVE27,NFIX,GPR173,PKM,KCTD15,FXYD1,SETD5,SGK1,SH3BP2,AMBRA1,R3HDM2,PEX26,TRIM67,IQSEC2,CDK19,SS18,USP22,TMEM9,NACC2,WBP2,UBTF,ZNF708,INTS3,CIAPIN1,URM1" MicroRNA hsa-miR-1976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-17 8.77E-14 3.41E-17 3.14E-16 63 501 "AS3MT,RNF157,ESYT2,CDC14B,SLC4A4,ALDH7A1,GPR146,RTTN,BAG4,CREM,ENTPD4,HINFP,CSNK1E,RIMS4,KIAA0408,DNAL1,WDPCP,CNNM1,MRNIP,RGS17,SLC43A2,TMEM132C,FKTN,FDFT1,FOXO3,AFF2,CRCP,KIAA1958,RNF165,ZDHHC15,EID2B,NCOA7,LSAMP,ALDH1L2,MTRF1L,EPDR1,APTX,ZSCAN2,TMEM231,ZNF844,NWD1,GTDC1,CYB561D1,PGBD4,RXRA,FAM192A,SCN2B,HSPA4L,ZFP30,PEX26,ZNF667,MPRIP,AGTPBP1,SATB2,TPCN2,PCDHA6,ZNF106,ARL10,ERCC6L2,USP1,AGMO,ZNF70,MPPE1" MicroRNA hsa-miR-3942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-17 1.00E-13 3.90E-17 3.59E-16 32 135 "BARD1,VXN,MATR3,FAM107B,KATNAL1,SUCO,UFM1,SRRM4,COPS8,TNRC6A,GNAL,ZBTB49,BACH2,KIAA1755,KCNN3,CREG2,KCTD6,PCSK1,PDPK1,EPB41L4B,MINDY2,BDNF-AS,SH3TC2,CCDC25,SGK1,ZFP30,NBPF1,TRIM67,FAM126B,TROVE2,NEK4,ATP6V0E2" MicroRNA hsa-miR-485-5p:PITA hsa-miR-485-5p:PITA_TOP PITA 1.88E-17 1.05E-13 4.09E-17 3.77E-16 38 194 "TAOK1,OGT,SEMA4G,ATP2B2,MAGI1,QKI,CNTFR,YTHDC1,RUSC2,TMCC2,DPH1,DRP2,PHC2,ELN,EPB41L2,NBEA,GABRB3,PPARGC1A,RNF165,IBA57,CAMK2N2,MYT1,NNAT,NOVA1,NTRK3,PDE1B,PLEC,PMP22,PSD,RIC8B,ZFHX4,KIRREL1,CHD9,FAM214B,SZT2,REEP1,CADM2,WNK3" MicroRNA hsa-miR-147:PITA hsa-miR-147:PITA_TOP PITA 1.90E-17 1.07E-13 4.13E-17 3.81E-16 34 154 "MAP4K3,ATP1A1,CACNA1A,CALM1,LDB2,AKAP6,CABP1,SPOCK2,DMTF1,KMT5B,ELN,EVL,KDM2B,GPD1,GRIN2D,HSF2,ZIC5,L1CAM,NF1,ZNF827,PDPK1,MINDY2,PRIMA1,ROBO2,PPP4R3A,TET1,STXBP1,CAMTA1,TCF4,SLC44A1,THRA,NR2C2,FLRT2,ADAMTS10" MicroRNA hsa-miR-519b-3p:Functional MTI Functional MTI miRTarbase 1.92E-17 1.07E-13 4.17E-17 3.84E-16 51 344 "TAOK1,SEMA7A,CFL2,EPS15L1,CLCN3,QKI,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,CERCAM,C3orf18,KATNAL1,ACSL4,FKTN,POLR1B,SEC23B,CELF1,GRB10,FICD,KCNB1,MBNL1,NBL1,CNOT4,CEP97,RBBP6,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,ATMIN,SATB2,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA "AACTGAC,MIR-223:MSigDB" "AACTGAC,MIR-223:MSigDB" MSigDB 2.13E-17 1.19E-13 4.62E-17 4.25E-16 27 93 "PLEKHH1,ALCAM,ZBTB10,PTBP2,QKI,SLC35F1,SACS,PHF20L1,OLFM1,FOXO3,RBPJ,IL6ST,INPP5B,STMN1,LMO2,MEF2C,MMP16,PDE4D,PDPK1,ANKRD16,MINDY2,WBP1L,FBXW7,SCAF8,SLC8A1,SOX11,UBTF" MicroRNA hsa-miR-589:PITA hsa-miR-589:PITA_TOP PITA 2.20E-17 1.23E-13 4.76E-17 4.38E-16 30 118 "PCDH19,SEMA6A,SPOP,GPRASP2,SYNJ1,CAMK2A,ZMYM4,MAGI1,AKAP6,RGS6,PLCXD3,GAPVD1,MED12L,NBEA,TNRC6A,KAT7,MAP2,MAT2A,MYO6,MYT1,NEFM,PURG,PRKAB2,SOX11,PEG10,SSTR1,SYN1,SZT2,TMEM237,WNK3" MicroRNA hsa-miR-154-5p:TargetScan hsa-miR-154-5p TargetScan 2.20E-17 1.23E-13 4.76E-17 4.38E-16 30 118 "BRAP,MTUS1,CDK13,CAMK2G,DCLK1,FOXN3,NRXN3,CLTC,GDA,DNAL1,DRP2,E2F5,LYVE1,LUZP2,KAT7,CDH20,MAP4,MYO6,CNOT4,PCSK5,SALL1,CSRNP3,FNIP1,CPEB3,PKNOX2,GPRIN3,CADM2,EVI5,FXR1,GAN" MicroRNA hsa-miR-770-5p:PITA hsa-miR-770-5p:PITA_TOP PITA 2.26E-17 1.27E-13 4.91E-17 4.52E-16 32 136 "CCDC85A,OGT,EIF4G3,CABP7,CNR1,SLITRK5,IST1,SACS,TMCC2,CPEB2,SLC12A6,MBNL2,RCAN2,EPHB1,RRAGB,GRIA2,STMN1,MARK1,MYO6,NCAM2,NTRK2,STRN3,PTX3,RAP1GDS1,GTDC1,FIGN,CPEB3,SP4,NMNAT2,ELOVL4,SZT2,TMEM178A" MicroRNA hsa-miR-1243:PITA hsa-miR-1243:PITA_TOP PITA 2.35E-17 1.32E-13 5.10E-17 4.70E-16 34 155 "ZNF608,MARCH3,SLC4A4,FAM19A5,AKAP7,ERC2,IST1,RAB39B,MBNL2,EGR3,RGS17,ERBB4,EYA1,SUCO,OGA,PPARGC1A,TOX3,GRIA2,IGF1,CNOT4,PCDH9,NLGN3,SEMA5B,VSTM2L,RXRA,SALL1,PEG10,ZC3H4,ANKRD28,WBP2,TMEM237,WNK3,RGS7BP,SOCS4" MicroRNA hsa-miR-3652:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-17 1.33E-13 5.15E-17 4.74E-16 55 397 "ABCF1,AS3MT,XKR4,RNF157,ESYT2,ARHGDIA,ISPD,DBT,HEYL,OPTN,TUBD1,COQ7,SEC23B,CINP,ZBED3,SPECC1,CELF1,GPR75,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,MKLN1,MMP17,ZNF713,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,PEX2,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,ANKRD36,ERC1,SSTR2,MPRIP,KLHL7,GPR161,ZNF34,ZNF106,ZNF24,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2,GAN" MicroRNA hsa-miR-4430:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-17 1.33E-13 5.15E-17 4.74E-16 55 397 "ABCF1,AS3MT,XKR4,RNF157,ESYT2,ARHGDIA,ISPD,DBT,HEYL,OPTN,TUBD1,COQ7,SEC23B,CINP,ZBED3,SPECC1,CELF1,GPR75,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,MKLN1,MMP17,ZNF713,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,PEX2,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,ANKRD36,ERC1,SSTR2,MPRIP,KLHL7,GPR161,ZNF34,ZNF106,ZNF24,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2,GAN" MicroRNA hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 2.49E-17 1.40E-13 5.39E-17 4.97E-16 36 175 "APBB2,IGDCC4,BACH1,NRP2,CACNB4,CAMK2G,CAPN3,CSF1,PLXNA4,GREB1,FGF14,ATP2C1,CHL1,NKD1,IL6ST,MEIS1,ADAM22,NDP,GPR137C,PCSK1,PDE3A,PTPRG,GTDC1,KLHL11,CPEB3,CHD9,EPC1,MBD5,PDZD2,BDP1,ELOVL4,KLHL7,BHLHB9,KCNK12,HNRNPA3,GAN" MicroRNA hsa-miR-3612:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-17 1.42E-13 5.51E-17 5.07E-16 57 424 "ABCF1,ADD2,TRMT9B,CPNE5,ARHGDIA,DDR1,LETMD1,CRY2,NCOR2,IPCEF1,RASSF2,LIN54,TMEM170A,DNAL1,SGSM2,SEC16A,RASA4,MRNIP,ANKMY1,KATNAL1,MRVI1,TRMO,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,DDX19B,IBA57,KLHL23,SAMD5,NBL1,TMOD2,PLEC,PLXNB1,RETREG2,ZNF793,SETD5,NCBP3,FAM102A,TRIM67,ATF7IP,ERC1,PEG10,IQSEC2,ZSCAN29,USP22,PPIL6,SSBP2,ZNF70,INTS3" MicroRNA hsa-miR-1298:mirSVR_highEffct hsa-miR-1298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-17 1.44E-13 5.56E-17 5.12E-16 41 228 "SRPX,EPB41L5,PLA2G4C,BMP7,CD38,ARMC8,BAG4,MYRIP,GDA,ERC2,DDX46,PDCD6IP,RGPD5,AP4B1,GABRG1,GHR,STARD3,GRIA2,DHX35,LRRCC1,SYTL4,MAP4,MXI1,HNRNPM,PCDH9,ZNF655,ANKRD16,PDZRN4,GRAMD1C,WDR25,CNTLN,RXRA,FHOD3,ZNF667,ANKRD36,SNAP25,NMNAT2,POGZ,ZFPM2,NAV3,CASC15" MicroRNA hsa-let-7i-5p:Functional MTI Functional MTI miRTarbase 2.62E-17 1.47E-13 5.66E-17 5.21E-16 50 334 "FZD9,MTUS1,ZNF578,EP400,AQP6,IGDCC4,BACH1,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,TRMO,PDLIM5,CELF1,DISC1,GATM,COPS8,POLL,FUT10,RABL2A,IGF1,IL6R,KPNA5,THYN1,SLC11A2,NUCB2,OPRL1,PIK3C2A,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,CBX5,TLR4,TUBB2A,ZNF28,SMARCAD1" MicroRNA hsa-miR-4713-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-17 1.51E-13 5.84E-17 5.38E-16 38 196 "PWWP2A,PTCHD1,PHF12,ARSE,ASPA,ZNF582,BACH1,CBS,PITPNM3,SPATA2,PHF20L1,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,ZNF638,KIAA1958,AP4S1,PADI2,KCNQ3,STMN1,LSAMP,MBNL1,NFYA,GNG2,SDK2,ZNF844,ZFP1,ZNF415,SMUG1,RUNDC3B,SSBP2,TSPAN11,ZNF781,ZNF138,DPYSL5,URM1,GAN" MicroRNA hsa-miR-411-5p.2:TargetScan hsa-miR-411-5p.2 TargetScan 2.81E-17 1.57E-13 6.07E-17 5.59E-16 28 102 "GALNT13,MTA3,LDLRAD4,RUNX1T1,CDH2,DCLK1,AKAP5,CCDC144A,EBF1,EGFR,MBNL2,ERBB4,CAMKK2,CELF1,RAPGEF6,IQGAP2,HLF,LIFR,MATN3,GPR173,LRP12,DCHS2,CSRNP3,FNIP1,CPEB4,NKAIN2,CLIP2,ELFN1" MicroRNA hsa-miR-455-5p:PITA hsa-miR-455-5p:PITA_TOP PITA 2.85E-17 1.60E-13 6.16E-17 5.67E-16 32 137 "ACTN1,UNC5A,INTS2,OSBPL1A,SEMA4G,CDK13,CACNB4,THSD7A,SLITRK5,ERC2,PLCXD3,DOCK4,MFAP3L,USP3,DTNB,EDN1,PLXNC1,FGF13,FRMD5,IBA57,NEXMIF,GPR85,KANSL1,EPDR1,RGS4,STX1B,CPEB3,SOX11,SATB2,DOCK9,CDH22,TRPS1" MicroRNA hsa-miR-1225-3p:mirSVR_highEffct hsa-miR-1225-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.85E-17 1.60E-13 6.16E-17 5.67E-16 46 286 "KCNH8,C1QTNF3,APAF1,MAGEE2,SPTBN4,NAE1,SCAPER,RUNX1T1,CBR1,CACNA2D2,PPT2,ABCG1,SEC24C,PDE4DIP,CYBB,DNM1,TOM1,ERBB2,TLR7,FHL1,NELFCD,AKAP3,TMEM107,GABBR1,GAD1,DISC1,GPR162,TCERG1,MCHR1,CLASRP,PSIP1,MSL1,GPR62,ZFYVE27,NEFM,NOVA1,PCDH9,PDE1B,PTN,CCDC25,RORB,MEG3,TSPYL2,USP32P1,BEX4,NDRG4" MicroRNA hsa-miR-876-5p:TargetScan hsa-miR-876-5p TargetScan 3.02E-17 1.69E-13 6.52E-17 6.00E-16 41 229 "AXIN2,HACE1,OGT,PARG,ARNTL,DST,FUBP1,MTMR3,QKI,LIN54,DBN1,MTX3,RGS17,DNAJC27,ANKFY1,CAMKK2,GLYR1,NEGR1,C2orf72,IL6R,KCNN3,MAP4,MBNL1,PPM1L,MN1,PAX6,GPR173,POU6F1,CNNM2,PTPRD,CEP97,KLHDC8A,RORB,RXRA,HKDC1,ATF7IP,PDZD2,ERC1,CUX2,NSD1,GPRIN3" MicroRNA hsa-miR-620:PITA hsa-miR-620:PITA_TOP PITA 3.03E-17 1.70E-13 6.53E-17 6.01E-16 35 166 "HECW2,SEMA6A,OGT,MARK4,LRBA,LHX2,SLC35F1,RIMS4,IST1,CPEB2,EDIL3,PHC2,APH1A,MBNL2,RGS17,ELN,KHDRBS3,PCLO,CIT,KIAA1755,MEF2C,KITLG,SCAMP5,CNTN3,OLA1,EPB41L4B,GTDC1,HECW1,LMO3,STAU1,RGL1,PLCB1,DICER1,RIMBP2,ST8SIA2" MicroRNA hsa-miR-1270:PITA hsa-miR-1270:PITA_TOP PITA 3.03E-17 1.70E-13 6.53E-17 6.01E-16 35 166 "HECW2,SEMA6A,OGT,MARK4,LRBA,LHX2,SLC35F1,RIMS4,IST1,CPEB2,EDIL3,PHC2,APH1A,MBNL2,RGS17,ELN,KHDRBS3,PCLO,CIT,KIAA1755,MEF2C,KITLG,SCAMP5,CNTN3,OLA1,EPB41L4B,GTDC1,HECW1,LMO3,STAU1,RGL1,PLCB1,DICER1,RIMBP2,ST8SIA2" MicroRNA hsa-miR-518c:mirSVR_highEffct hsa-miR-518c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.20E-17 1.79E-13 6.89E-17 6.34E-16 45 275 "AXIN2,LRFN2,ZNF608,PCDH19,CASK,CFAP410,PPT2,AKAP6,SMARCAL1,SOCS5,DTNA,EDN1,GMPR2,ACSL4,GORAB,FHL1,SYT17,KDM2B,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,RTL5,ZC3H12B,ZNF827,SH3KBP1,APTX,TMEM255A,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,TBCEL,NSD1,KAT6B,TSN,PLEKHH2,KCNK12,EMSY,PRTFDC1,TUBA1A,PARP11" MicroRNA hsa-miR-615-3p:mirSVR_lowEffct hsa-miR-615-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.24E-17 1.81E-13 6.97E-17 6.42E-16 48 311 "KCNH8,ZNF687,TMEFF1,RGS20,ASGR1,PTBP2,ASIC3,SH2B1,NCOR2,RGS6,DCAF8,CHRDL1,EDN3,ELN,SPEG,RASL12,FLT1,TMEM107,LRRC37A6P,SPIN1,RABL2A,ADAMTS6,FRMD3,FAM95B1,SCIN,RTL5,NME4,DNHD1,FAM216A,POLR2F,PCDHB17P,VSTM2L,BCAS3,FAM66C,PRRT2,UBR7,CARF,ABLIM3,RGL1,DICER1-AS1,PIK3R5,TRO,CLIP2,ZNF213,SEMA3B,TRIM16L,DOCK8,JPH3" MicroRNA hsa-miR-7111-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-17 1.99E-13 7.65E-17 7.05E-16 40 219 "ADCY6,TNRC6C,LDLRAD4,RUNX1T1,LRRFIP1,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,KIAA0408,IP6K1,TMCC2,DPYSL2,ANKMY1,REEP2,SCML2,AMOTL2,HHIPL1,ZNF638,GRM8,KCNN3,SYTL4,MBNL1,POLG,POU6F1,KANSL1,ZNF844,C12orf49,ELP2,ZFP30,SLC6A8,ERC1,SEPT8,VPS13A,CRTC1,UGT8,AMZ1,DPYSL5,FRMD6" MicroRNA hsa-miR-296-5p:TargetScan hsa-miR-296-5p TargetScan 3.58E-17 2.01E-13 7.71E-17 7.10E-16 32 138 "LRFN1,PPFIA3,ARRB1,CCAR2,GPC2,DDR1,NUMBL,IGLON5,CNR1,CNTFR,NRG2,SEC31B,CLIP3,RIMS4,DBN1,PHC2,HEYL,MFSD10,FGFR1,INPP5K,CYP46A1,POLL,RNF165,NOVA2,KCTD15,CNNM2,RAD51D,DPF2,PRRT2,ELMO2,NSD1,ADAMTS10" MicroRNA hsa-miR-541:mirSVR_highEffct hsa-miR-541:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.73E-17 2.09E-13 8.02E-17 7.38E-16 61 482 "ASIC1,NDRG3,ALCAM,PHF12,ADAM23,AZGP1,SYNJ1,SCAPER,RAB29,LARGE1,PPT2,FHL5,COL4A5,SLC4A8,CLIP3,TRIM69,GAPVD1,ZBTB24,ELMO1,DNAJB6,FCF1,EGFR,TMEM35A,EPB41L2,MRPL37,PPP1R1B,SPECC1,RASL10A,GLYR1,GNAL,LOXL3,CLASRP,TOX2,MAN1B1,CFAP126,HSPA1L,INPP5B,MBD1,NNAT,CNOT4,NTRK2,GNG2,SEPT4,BCAS3,HKR1,RGS12,ATXN2,KIF21A,ATF7IP,ARFGAP1,SNRPN,ST5,PHLDB1,SEPT3,KLHL7,ARC,PCDHB9,TPM2,OSBP2,TRIM9,NAV3" MicroRNA hsa-miR-29a-3p:Functional MTI Functional MTI miRTarbase 4.08E-17 2.28E-13 8.77E-17 8.07E-16 44 265 "BCL7A,QKI,ELMSAN1,FEM1B,RASGRP1,GOLGA7,ELN,SYNCRIP,FOXO3,DOT1L,GLUL,HMGCR,IGF1,GAREM2,LAMA2,LIMS1,MYCN,HNRNPM,ENPP2,GPR85,PIK3R1,KCTD15,TRIM68,RET,GTDC1,RNASEL,ROBO1,GLDN,S100B,SARS,SGK1,CPEB3,SEC31A,TET1,CPEB4,MAPKBP1,SP2,HECW1,DICER1,TUBB2A,CCDC14,TMEM237,ADAMTS9,NAV3" MicroRNA hsa-miR-557:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-17 2.35E-13 9.03E-17 8.31E-16 37 188 "KCTD16,SEMA6A,BACH1,BCL7A,BID,JAZF1,CALM1,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,GUCD1,EDN1,STARD3NL,SLC43A2,ACSL4,SCML2,FER,PRRC2B,BACH2,RBPJ,LIMS1,P2RY1,PLIN1,STRN3,ACSS3,NWD1,KCNIP3,SATB1,PEX26,SLC8A1,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-507:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-17 2.35E-13 9.03E-17 8.31E-16 37 188 "KCTD16,SEMA6A,BACH1,BCL7A,BID,JAZF1,CALM1,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,GUCD1,EDN1,STARD3NL,SLC43A2,ACSL4,SCML2,FER,PRRC2B,BACH2,RBPJ,LIMS1,P2RY1,PLIN1,STRN3,ACSS3,NWD1,KCNIP3,SATB1,PEX26,SLC8A1,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-183-5p:Functional MTI Functional MTI miRTarbase 4.54E-17 2.54E-13 9.75E-17 8.98E-16 51 351 "ABCF1,SLC24A4,MTUS1,ZFAT,ARHGDIA,STK33,TMEM108,SOCS6,BAG4,AKAP12,CS,PITPNM3,PHF14,ARHGAP32,DBT,GUCD1,RACK1,SUCO,CELF1,USP19,GPR75,GLUL,FUT10,ITPKB,KLHL23,KIF2A,HNRNPM,PFKFB3,KCTD15,PIGG,ZIK1,REV3L,ZFHX4,PPP4R3A,ANKRD36,RBM34,MYCBP2,ERC1,ZNF621,SSTR2,ERBIN,MPRIP,ZC3H4,SIN3B,ZEB1,USP22,TRO,TUBB1,RPL7L1,ZNF24,RTN4" MicroRNA hsa-miR-133a:PITA hsa-miR-133a:PITA_TOP PITA 4.70E-17 2.63E-13 1.01E-16 9.30E-16 42 243 "PITPNM2,PPFIA3,ARHGDIA,CDK13,JAZF1,CALM1,PTBP2,USP6,QKI,TBPL1,ZNF385A,CSNK1G3,RIMS4,MAML1,ZC3H11A,PAN3,MED12L,FGF1,DOT1L,SESN1,TTBK1,TMEM121B,FRMD5,RBPJ,SFXN5,MEIS1,MEIS2,NTRK3,TRHDE,SNRK,PTPRD,PTPRO,SCN2B,CASC3,SGK1,BTBD3,SYT1,ANKRD28,ANKRD12,FBXW11,PHF24,CELF4" MicroRNA hsa-miR-133b:PITA hsa-miR-133b:PITA_TOP PITA 4.70E-17 2.63E-13 1.01E-16 9.30E-16 42 243 "PITPNM2,PPFIA3,ARHGDIA,CDK13,JAZF1,CALM1,PTBP2,USP6,QKI,TBPL1,ZNF385A,CSNK1G3,RIMS4,MAML1,ZC3H11A,PAN3,MED12L,FGF1,DOT1L,SESN1,TTBK1,TMEM121B,FRMD5,RBPJ,SFXN5,MEIS1,MEIS2,NTRK3,TRHDE,SNRK,PTPRD,PTPRO,SCN2B,CASC3,SGK1,BTBD3,SYT1,ANKRD28,ANKRD12,FBXW11,PHF24,CELF4" MicroRNA hsa-miR-873-5p.1:TargetScan hsa-miR-873-5p.1 TargetScan 4.72E-17 2.64E-13 1.01E-16 9.31E-16 44 266 "HECW2,APC,MARK4,BCL7A,BMP7,CACNA1I,CBFA2T2,NRXN3,GPRASP1,MATR3,JAKMIP2,MYEF2,RGS17,HPCAL4,JKAMP,ERAP1,PADI2,HMGCR,PPM1L,MN1,SAMD14,HNRNPM,CLDN11,PCSK5,PDE4D,GDPD1,PIGG,RASGRF1,DPF2,KLHL11,MCMBP,HUNK,KCNIP3,FAM192A,PRCD,HSPA4L,EPC1,ALG1,EML6,DNALI1,GDPD5,HNRNPA3,FXR1,NETO1" MicroRNA hsa-miR-147a:Functional MTI Functional MTI miRTarbase 5.07E-17 2.84E-13 1.09E-16 1.00E-15 33 149 "SEMA6A,CARNS1,CACNA1A,RUNX1T1,TMEM184B,IGLON5,CLOCK,PPP1R16B,DCAF8,JAKMIP2,TMEM130,DMD,DMTF1,MRPL37,FGF14,CAMKK2,CBX1,PRRC2B,NKD1,KCNB1,IPO5,MAP2,MITF,HS6ST3,ZNF655,SDK2,SATB1,ZEB1,HIF3A,VSNL1,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-198:PITA hsa-miR-198:PITA_TOP PITA 5.07E-17 2.84E-13 1.09E-16 1.00E-15 33 149 "ATP1A3,ADGRB3,JAZF1,CAMK2G,FOXN3,SEC24C,SLITRK5,ERC2,DPP6,APH1A,MBNL2,AGAP3,KDM2B,KCND1,CHIC1,MEIS1,CNOT4,RETREG1,LRRN3,PRKAB2,PSD,FIGN,ATXN7,ZNF821,SH3GL3,PKNOX2,SLC8A1,CDK19,POGZ,FBXW11,TCEA1,PUM2,SOCS4" MicroRNA hsa-miR-340*:mirSVR_highEffct hsa-miR-340*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.33E-17 2.98E-13 1.14E-16 1.05E-15 53 378 "APLP1,BACH1,GYG2,CALM1,SLC16A4,P2RX6,CD38,NOG,PPT2,SLC35F1,CSF2RA,TMEM170A,GUCD1,FCF1,IRAK4,STX2,ZNF549,RACK1,PDLIM5,TRIM16,GALNT15,SIGLEC8,COPS8,SPACA9,ATXN2L,INPP5B,IPO5,RETREG2,ZSCAN2,RADX,TRIM68,SNX22,RPL15,GLDN,MAPK12,ZFP30,SH3GL3,R3HDM2,RADIL,SLC12A2,ANKRD36,PDZRN3,RBM34,ZSWIM8,ERC1,SPTAN1,PCDHB9,DICER1-AS1,PPIL6,VIPR2,WIPF1,DNALI1,TRIM16L" MicroRNA hsa-miR-6780a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.05E-17 3.38E-13 1.30E-16 1.19E-15 37 190 "TNRC6C,LDLRAD4,RUNX1T1,LRRFIP1,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,IP6K1,TMCC2,DPYSL2,NCALD,ANKMY1,REEP2,TAOK3,SCML2,CELF1,HHIPL1,ZNF638,GRM8,SYTL4,MBNL1,PKM,POLG,PRKCB,ZNF844,ELP2,ZFP30,SLC6A8,SEPT8,VPS13A,UGT8,ZNF154,AMZ1,UPF3A,FRMD6" MicroRNA hsa-miR-566:mirSVR_lowEffct hsa-miR-566:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.21E-17 3.48E-13 1.33E-16 1.23E-15 48 316 "EMILIN3,ADCY6,MARCH4,CDC14B,MARCH3,CHID1,CFAP410,PRC1,CBARP,ARHGAP22,WHRN,CABP1,GIT2,DGCR5,DNAH9,DTNB,EDN1,TMEM132E,FGF1,FHL1,SDCBP2,ERAP1,SPIN1,STARD3,SPACA9,CACFD1,CELF5,MBNL1,TM6SF1,MPP2,SFR1,CDK18,PDE4D,NECAB2,RBBP8,DCUN1D2,CCDC25,HSD11B1L,ST6GALNAC6,SUPT20H,ANKRD36,KIF13A,KDM4C,KANK1,SEPT3,LINC02210,SIGLEC10,FAM47E" MicroRNA "GTGACTT,MIR-224:MSigDB" "GTGACTT,MIR-224:MSigDB" MSigDB 6.28E-17 3.51E-13 1.34E-16 1.24E-15 33 150 "APBA2,USP37,SLC4A4,ATP1B3,CAST,FOXN3,QKI,DNM1,CPEB2,DPYSL2,MBNL2,ACSL4,AMOTL2,FAM49B,TCERG1,CIT,HMGCR,STMN1,PAXBP1,MBNL1,ZNF655,PTX3,ZFHX4,CASC3,TRA2B,KDM3A,ZNF423,SEPT3,SYP,PUM2,TRIM9,SMARCAD1,ZDHHC20" MicroRNA hsa-miR-433:PITA hsa-miR-433:PITA_TOP PITA 6.39E-17 3.58E-13 1.37E-16 1.26E-15 42 245 "XKR4,INTS2,HECW2,PCDH19,ZBTB10,USP6,MAGI1,FOXN3,QKI,SACS,WDR20,RAB39B,YAF2,COPS4,ERBB4,ETV1,PRKAG2,ST6GALNAC3,OGA,PPARGC1A,FERMT2,NEGR1,MXI1,GPR137C,MAPK9,MTMR10,TTC13,RAP1GDS1,PBRM1,FBXW7,CLIP1,CSRNP3,CHD9,EPN2,PDZRN3,VPS13A,ANKRD12,CAMTA1,FAM208A,TRIM2,TSC1,PLEKHH2" MicroRNA hsa-miR-151-3p:PITA hsa-miR-151-3p:PITA_TOP PITA 6.48E-17 3.63E-13 1.39E-16 1.28E-15 28 105 "SPAG9,ARMC8,RGS6,SOCS5,MBNL2,EIF4G2,DLC1,ZMAT1,CHL1,GHR,PCLO,GRB10,PSIP1,MIER3,LRRTM1,RYR3,TRA2B,HSPA4L,CLASP2,LARP4,ZFPM2,TRPS1,TBC1D15,ZFAND5,SMARCAD1,NAV3,FXR1,NETO2" MicroRNA hsa-miR-548h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.52E-17 3.65E-13 1.39E-16 1.28E-15 46 292 "TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,MTMR3,FAM169A,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,THYN1,MYO6,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,ATF7IP,FAM126B,FAM208A,ALG1,CLASP1,ARL10,MKRN3,GAL3ST3" MicroRNA hsa-miR-548bb-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.52E-17 3.65E-13 1.39E-16 1.28E-15 46 292 "TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,MTMR3,FAM169A,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,THYN1,MYO6,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,ATF7IP,FAM126B,FAM208A,ALG1,CLASP1,ARL10,MKRN3,GAL3ST3" MicroRNA hsa-miR-548z:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.52E-17 3.65E-13 1.39E-16 1.28E-15 46 292 "TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,MTMR3,FAM169A,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,THYN1,MYO6,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,ATF7IP,FAM126B,FAM208A,ALG1,CLASP1,ARL10,MKRN3,GAL3ST3" MicroRNA hsa-miR-1468:mirSVR_highEffct hsa-miR-1468:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.66E-17 3.73E-13 1.42E-16 1.31E-15 52 367 "CEP126,AMPD3,LCORL,CALB1,CAMK2G,ZNF501,LRRFIP1,CFL2,CLCN3,TBPL1,UBXN2A,CTH,TCAF1,KIAA0753,DMTF1,DTNA,DNM1L,EDNRB,FCF1,MBNL2,ABCA8,MEX3B,ZMYND15,NOP56,NELFCD,C2orf88,TVP23A,HTATSF1,IGFBPL1,ZNF678,LAMP2,SRSF12,OPA1,JAKMIP1,PTN,TMEM255A,TRIM68,PRRT2,SPIN3,MCMBP,SYBU,NLGN1,FAM81A,ADAMTS17,TCEA1,NEIL2,PLEKHH2,USP1,WIPF1,TRIM9,FTSJ1,ZDHHC20" MicroRNA "CTACTGT,MIR-199A:MSigDB" "CTACTGT,MIR-199A:MSigDB" MSigDB 6.68E-17 3.74E-13 1.43E-16 1.31E-15 35 170 "PLEKHH1,ARHGAP20,DPP10,ANK2,PHF12,SLC4A4,NRP2,DGKI,QKI,ARHGAP24,TSPAN5,CALCRL,ETV1,FGF12,PSD2,ZNF638,FAM222A,ZHX1,LIFR,HECTD2,MAP6,MBNL1,MEIS2,NFE2L2,NOVA1,PPP2R5E,PTX3,BTBD7,CPEB4,KDM3A,CAMTA1,CDH22,VLDLR,ADAMTSL3,FXR1" MicroRNA hsa-miR-1263:PITA hsa-miR-1263:PITA_TOP PITA 6.99E-17 3.91E-13 1.49E-16 1.37E-15 27 97 "ADRA1B,MAP4K3,CADPS,NCOA1,STX16,BCL7A,CACNA1A,PLCXD3,LYPD1,SNAP91,YAF2,MTHFD2,LRRTM1,MAT2A,MID1,PCDH9,MAPK10,PPM1E,FBXO11,PHLDB1,PRRC2C,ARHGEF9,NSD1,DICER1,TP53BP2,TRIM9,HNRNPA3" MicroRNA hsa-miR-383-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-17 3.92E-13 1.49E-16 1.37E-15 56 420 "XKR4,PLEKHH1,TRMT9B,STX16,SYNJ2,LONRF2,AKAP5,USP6NL,DNAL1,SLC29A4,MRO,PLEKHA1,ING4,IGSF6,TMEM164,ANKFY1,CACFD1,BVES,IRAK3,MATN3,PPM1L,ZC3H12B,ZNF713,PDPK1,GPSM2,STRN3,APTX,MTMR10,CEP97,ZMAT4,C12orf49,ELP2,R3HDM2,SLC2A5,SEPHS1,INAVA,MCF2L2,SS18,ZSCAN29,NEK4,SLC37A2,FAM208A,CLASP1,CBX5,ERCC6L2,TUBB2A,RPL7L1,ZNF708,ZNF17,ZNF45,DHX33,EVI5,STOX2,URM1,FBXO36,ZDHHC20" MicroRNA hsa-miR-542-3p:PITA hsa-miR-542-3p:PITA_TOP PITA 7.24E-17 4.05E-13 1.54E-16 1.42E-15 37 191 "SYS1,OSBPL8,ALCAM,SLC4A4,LDLRAD4,CALM1,SPAG9,QKI,HECTD1,TBPL1,CLIP3,DBT,CNNM1,SPSB4,AFF2,PCDH17,PTPRT,ZIC5,NOVA1,PIK3R1,STRN3,REV3L,FNDC3A,FHOD3,R3HDM2,SLC12A2,SOX11,ANKRD28,CUX2,TCF12,DOCK9,PUM2,CSMD1,TPM1,PCDH20,ZIC1,EMSY" MicroRNA hsa-miR-5196-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.33E-17 4.10E-13 1.56E-16 1.44E-15 47 305 "ELFN2,TRMT9B,ARHGDIA,ARRB2,TTLL9,BCL7A,ZNF385A,CRY2,RGS6,PPP1R16B,APH1A,MRO,ASB3,MTHFD2,GFER,TNRC6A,LILRA2,GSN,NXPH3,TNFAIP8L3,SHISA6,MAT2A,NFIX,PDE3A,PKM,KCTD15,NLE1,FXYD1,IQSEC3,PRRT2,ERI2,SETD5,SEMA6D,SBF1,SHMT2,PEX26,MPRIP,NACC2,ASXL3,BHLHB9,WBP2,TUBB2A,INTS3,URM1,ITM2C,WNK2,ZDHHC20" MicroRNA hsa-miR-4747-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.33E-17 4.10E-13 1.56E-16 1.44E-15 47 305 "ELFN2,TRMT9B,ARHGDIA,ARRB2,TTLL9,BCL7A,ZNF385A,CRY2,RGS6,PPP1R16B,APH1A,MRO,ASB3,MTHFD2,GFER,TNRC6A,LILRA2,GSN,NXPH3,TNFAIP8L3,SHISA6,MAT2A,NFIX,PDE3A,PKM,KCTD15,NLE1,FXYD1,IQSEC3,PRRT2,ERI2,SETD5,SEMA6D,SBF1,SHMT2,PEX26,MPRIP,NACC2,ASXL3,BHLHB9,WBP2,TUBB2A,INTS3,URM1,ITM2C,WNK2,ZDHHC20" MicroRNA hsa-miR-548ac:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.46E-17 4.17E-13 1.59E-16 1.46E-15 46 293 "TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,MTMR3,FAM169A,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,THYN1,MYO6,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,ATF7IP,FAM126B,FAM208A,ALG1,CLASP1,ARL10,MKRN3,GAL3ST3" MicroRNA hsa-miR-876-3p:PITA hsa-miR-876-3p:PITA_TOP PITA 7.65E-17 4.28E-13 1.63E-16 1.50E-15 30 123 "SEMA6A,MTMR3,CALM1,CAMK2G,DMD,ST3GAL6,PPARGC1A,BRD8,LOXL3,CIT,MEIS1,NEXMIF,ANKRD16,MINDY2,PTPRD,RBBP6,RDX,ZMAT4,SMPD3,SGK1,CPEB4,SNAP25,KDM4B,TEX2,POGZ,SYP,PDSS1,UBTF,NAV3,HNRNPA3" MicroRNA hsa-miR-429:Functional MTI Functional MTI miRTarbase 7.76E-17 4.34E-13 1.65E-16 1.52E-15 33 151 "TXNDC16,CDC14B,ARHGDIA,STX16,SEPT7,QKI,BAG4,PHF14,RASSF2,MAMLD1,DNAJB6,ACSL4,DLC1,CELF1,SESN1,MALT1,RASSF8,TJAP1,PDPK1,PKD1,MAPK7,PTPRD,ZFHX4,WDR37,ELMO2,MBD5,KIF13A,ZNF621,ERBIN,ZEB1,ZFPM2,ZMAT3,TUBB2A" MicroRNA hsa-miR-542-3p:TargetScan hsa-miR-542-3p TargetScan 8.00E-17 4.48E-13 1.70E-16 1.57E-15 43 258 "C3orf14,ALCAM,DPP10,APBB2,MARCH3,BMP7,RUNX1T1,C1orf52,NRXN3,RCHY1,C2CD2,NCOR1,DBT,DDX46,CDON,HIPK3,CNNM1,EIF5,EIF1,MRVI1,F8,FGF12,MEGF11,PCDH17,PTPRT,KLHL23,LSAMP,MID1,MMP16,DBNL,SAMD14,NOVA1,PDE4D,ROBO1,CSRNP3,PRCD,FHOD3,R3HDM2,KDM3A,CUX2,PUM2,CBX5,MFF" MicroRNA hsa-miR-649:PITA hsa-miR-649:PITA_TOP PITA 8.03E-17 4.49E-13 1.71E-16 1.57E-15 39 213 "ALCAM,NCOA1,CAMK2G,CS,RIMS2,GAPVD1,SNAP91,CHRDL1,DMTF1,PDCD6IP,YAF2,DCTN4,EIF1,EMX2,EPB41L2,JKAMP,SESN1,PCDH17,PPARGC1A,KIAA1958,BACH2,MYLK2,ZIC5,MEIS2,KITLG,MID1,PPM1E,WDR37,PPP4R3A,CCDC88A,TET1,POGZ,LARP4,TCF4,PUM2,PCDH20,NAV3,KAT6A,CPNE4" MicroRNA "GCTTGAA,MIR-498:MSigDB" "GCTTGAA,MIR-498:MSigDB" MSigDB 8.50E-17 4.76E-13 1.81E-16 1.66E-15 28 106 "NCOA1,C5,CAMK2G,CELF1,FERMT2,GRIA2,PACSIN2,BACH2,AGBL5,DHX35,KCND2,STXBP5,LRP1B,MEIS1,PDE4B,PIK3R1,PURG,EPB41L4B,PPP3CA,SNRK,FAM214B,PKNOX2,ABTB1,SOX11,ANKRD28,DICER1,FLRT2,ST8SIA2" MicroRNA hsa-miR-450a:mirSVR_highEffct hsa-miR-450a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.13E-17 5.11E-13 1.94E-16 1.79E-15 48 319 "GALNT16,KIAA1211,ZNF608,KIAA1324,VAT1L,TTLL9,RAB33A,AKAP7,RTTN,MYRIP,SLC35F1,CPS1,RIPOR2,DGKB,HEPH,PLPPR4,EGFR,KMT5B,EPHB1,F8,ST3GAL6,SMC2,ADGRA3,CYP27C1,KTN1,PAXBP1,MATN3,MEIS1,MITF,MMP16,COL28A1,PCSK1,KANSL1,PTN,ZNF615,CRTAC1,ATP8B4,RPS20,FNIP1,BTBD3,ZNF667,SAMSN1,PCDHGB7,DCBLD1,CLDND1,ELFN1,SMARCAD1,TRAM2-AS1" MicroRNA hsa-miR-3667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.44E-17 5.28E-13 2.01E-16 1.85E-15 40 225 "XKR4,ASGR1,DDR1,LURAP1,LRRFIP1,B4GALT6,NRXN3,PDE4DIP,PITPNM3,PLCXD3,RASSF2,IP6K1,USP3,OPTN,ERBB2,ANKMY1,REEP2,HHIPL1,SRRM4,LYVE1,TXNL4A,TCERG1,FAM107A,PADI2,ELOVL5,HMGCR,KIF5A,MEIS1,MN1,MYO5A,PKD1,POLG,PRKCB,BCAS3,MSANTD2,GTDC1,KIRREL1,ZFP30,NSFL1C,NSD1" MicroRNA hsa-miR-939:PITA hsa-miR-939:PITA_TOP PITA 9.49E-17 5.31E-13 2.01E-16 1.85E-15 26 90 "NDRG3,CASKIN1,SEMA4G,ADGRB1,CACNA1A,DCLK1,TAOK2,SLC35F1,PHC2,ELN,AGAP3,USP21,CPLX2,GRIN2D,KAT7,LRRC75A,CAMK2N2,MN1,GIT1,MSI1,ZNF827,PDE1B,PEAR1,SLC11A1,NFASC,SZT2" MicroRNA "GTTATAT,MIR-410:MSigDB" "GTTATAT,MIR-410:MSigDB" MSigDB 9.49E-17 5.31E-13 2.01E-16 1.85E-15 26 90 "FMNL2,CASK,NUMB,ATP2B2,NRXN3,FAM19A5,QKI,DPYSL2,YAF2,PHF20L1,MSTN,GRIA2,MAP4K5,ITPKB,LAMP2,SCAMP5,NTRK2,PCDH8,RDX,CPEB3,CPEB4,SP4,SYN2,ANKRD12,DOCK9,KAT6A" MicroRNA hsa-miR-5693:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-16 5.87E-13 2.23E-16 2.05E-15 51 358 "ABCF1,CLK4,AS3MT,XKR4,TXNDC16,DOCK11,GREB1,IP6K1,YTHDC1,KRBA2,TUBD1,POLR1B,SEC23B,MSANTD4,KAT7,SHISA6,IBA57,LIMS1,GPR155,MAP4,LYPLAL1,ZNF713,OLA1,GPSM2,APTX,PEX2,SH3TC2,RAP1GDS1,ERI2,C12orf49,ELP2,SNX22,NCBP3,HSPA4L,SH3BP2,R3HDM2,PEX26,SLC8A1,ANKRD36,BDP1,ZNF621,ZSCAN29,KLHL7,ALG1,ZNF34,ZNF106,LAT2,ZNF708,EVI5,RNF170,AP3B2" MicroRNA hsa-miR-551b:mirSVR_lowEffct hsa-miR-551b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-16 6.22E-13 2.36E-16 2.17E-15 44 272 "KDM5D,DPP10,CACNA1B,RUNX1T1,P2RX6,PPT2,COL4A5,APPL1,CENPL,MFAP3L,HIPK3,PHF20L1,GOLGA7,VPS13B,ERBB2,ERBB4,ANKMY1,FGFR1,DISC1,ADAM28,LNX1,SFXN5,MBP,ADAM11,MEIS1,OGG1,ING3,PPP2R2B,RAD51D,GTDC1,ABCA11P,KCNIP3,COPZ1,FAM81A,SNRPN,KDM4B,ZC3H13,LHPP,CEP68,ARHGEF9,RNF103,EPM2A,FBXO36,KLHDC1" MicroRNA hsa-miR-640:PITA hsa-miR-640:PITA_TOP PITA 1.19E-16 6.65E-13 2.52E-16 2.32E-15 35 173 "ZNF608,INTS2,GPRASP2,JAZF1,FOXN3,CLTC,CNR1,ABI3BP,TIAM2,EIF5,EXTL2,DLC1,AFF2,OGA,PCLO,STMN2,CDH20,MBNL1,KITLG,NOVA1,PBRM1,ATXN7,SCP2,TMCC1,FAM126B,POGZ,CAMTA1,WSCD1,SATB2,DICER1,VLDLR,PCDH20,NAV3,FZD3,HNRNPA3" MicroRNA hsa-miR-342-5p:mirSVR_highEffct hsa-miR-342-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-16 7.27E-13 2.75E-16 2.53E-15 50 347 "PDZD4,SPTBN4,CCAR2,KSR1,CASTOR3,MTMR2,DDR1,PLEKHB1,DGCR9,CNTFR,WHRN,SEC24C,KLHL3,SNAP91,DPH1,DTNA,PHF20L1,HSPA12B,ACSL4,GTF2IRD2,FGF11,SUCO,SIGLEC8,PPARGC1A,GPD2,FAM222A,SLC35G1,MMP16,MN1,OCRL,PTPRH,PTPRN2,TMEM255A,OXR1,RDX,MEG3,ATAT1,CPEB3,KBTBD4,SLC12A4,ATF7IP,KIF13A,NFASC,STXBP1,MLST8,OBSL1,TNS2,GAL3ST3,FAM47E,UBE3B" MicroRNA hsa-miR-193b:PITA hsa-miR-193b:PITA_TOP PITA 1.35E-16 7.56E-13 2.86E-16 2.64E-15 32 144 "KCNH8,UPRT,STX16,CALB1,CALM1,RUNX1T1,FAM131B,ZC3H11A,ETV1,FGF1,ANKFY1,ST6GALNAC3,GNAO1,CAMK2N2,STMN1,MYCN,NEXMIF,NOVA1,CCSER2,MSANTD2,ZHX3,HECW1,ERBIN,ST5,CAMTA1,AGTPBP1,TCF4,DMXL2,LRRC8A,R3HDM1,NAV3,RNF146" MicroRNA hsa-miR-18a-5p:Functional MTI Functional MTI miRTarbase 1.43E-16 8.00E-13 3.03E-16 2.79E-15 43 262 "ABR,AS3MT,RNF157,PTCHD1,TAOK1,ATP1A1,ADAM15,CA12,LARGE1,TBPL1,DCAF4,DCAF8,LIN54,MATR3,KLHL3,ZNF585B,RACK1,SEC24B,DCTN2,NBEA,MSL3,BVES,AGFG1,HSF2,RBPJ,ZNF678,MBD1,MID1,PCDH9,PDE4D,PSAT1,CSRNP3,CDK19,SYPL1,DICER1,THRA,UBC,RICTOR,ZNF711,ZNF708,ZFAND5,ITM2C,RNF146" MicroRNA hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-16 8.46E-13 3.20E-16 2.95E-15 48 323 "AS3MT,MTA3,SORCS2,SPOP,ATP1A3,PROM1,CABP7,CD86,CST3,PLXNA4,PITPNM3,KIAA0408,GAPVD1,RCAN1,EMX2,NRN1,GABRG2,PCDH17,PARD3B,FRMD3,LSAMP,PALM,PDE3A,PLCL1,KANSL1,SNRK,RDX,SCN2B,ZFP30,CPEB3,ZFP1,LIMCH1,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,MGRN1,BHLHB9,TNS1,TSC1,UBE2H,ZNF708,CADM2,PRDM10,MPPE1,DPF3" MicroRNA hsa-miR-4455:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-16 1.00E-12 3.79E-16 3.49E-15 34 165 "PTCHD1,MARCH4,ARHGDIA,MARCH3,PPP1R16B,PYGO1,DBT,JAKMIP2,DMD,CDON,PLEKHA1,KATNAL1,FGF14,ZBED3,GLI2,CBX1,KCNQ3,MPP2,DBNL,MYO5A,PRKCB,MAPK10,SH3TC2,PRRT2,SETD5,PGBD4,NMNAT2,CAMTA2,ZC3H4,CUX2,ZEB1,NACC2,NR2E1,ZDHHC20" MicroRNA hsa-miR-6787-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-16 1.02E-12 3.84E-16 3.54E-15 42 252 "CLK4,AS3MT,MTA3,TAOK1,STX16,DOCK11,RTTN,ENTPD4,PLXNA4,UBXN2A,FBXL5,HEYL,MRO,MRNIP,COQ7,IGSF6,DOT1L,GPR75,KDM2B,LILRA2,KAT7,ZNF546,GPR155,SAMD5,FITM2,CEP97,ZNF793,PGBD4,PTGR2,PEX26,ATF7IP,ERC1,ZNF621,SSTR2,ALG1,AGTPBP1,SLC19A3,SMUG1,MGAT5B,DPYSL5,URM1,MPPE1" MicroRNA hsa-miR-654-5p:mirSVR_highEffct hsa-miR-654-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.96E-16 1.09E-12 4.14E-16 3.81E-15 59 471 "ASIC1,NDRG3,PHF12,ADAM23,AZGP1,SYNJ1,SCAPER,RAB29,LARGE1,PPT2,FHL5,COL4A5,SLC4A8,CLIP3,TRIM69,GAPVD1,ZBTB24,ELMO1,ECM2,DNAJB6,FCF1,EGFR,MRPL37,PPP1R1B,SPECC1,RASL10A,GLYR1,LOXL3,CLASRP,TOX2,MAN1B1,CFAP126,IDH3B,INPP5B,MBD1,NNAT,CNOT4,NTRK2,PFKFB2,BCAS3,HKR1,RGS12,RPL15,DGLUCY,ATXN2,KIF21A,ATF7IP,ARFGAP1,SNRPN,ST5,PHLDB1,SEPT3,KLHL7,ARC,PCDHB9,TPM2,OSBP2,TRIM9,SLC30A3" MicroRNA hsa-miR-214*:mirSVR_highEffct hsa-miR-214*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-16 1.15E-12 4.36E-16 4.02E-15 53 390 "KLHL32,ADCY6,BEND6,DPY19L2P4,RTL9,OSBPL6,AK2,SPOP,SYNJ2,PTBP2,SUMF2,MYRIP,PHF14,USP3,EBF1,EDN3,PHF20L1,APH1A,AASS,EYA1,RPS6KC1,SPECC1,TMEM8B,SESN1,TDRKH,PACSIN2,NCKAP1L,KCNN3,CREG2,CYP27C1,L1CAM,MBNL1,OGG1,P2RX7,CDK18,GPR173,RETREG1,SH3KBP1,STRC,CCDC82,CCDC102B,FERMT1,RCOR3,CEP68,WSCD1,SLC44A1,ARL10,SMUG1,ZKSCAN5,CELF4,SPIRE1,PRTFDC1,LAS1L" MicroRNA hsa-miR-629-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-16 1.16E-12 4.39E-16 4.04E-15 37 197 "TNRC6C,SEMA4G,ASPA,ATP1B3,BACH1,CBS,RGS6,PITPNM3,SPATA2,PHF20L1,EMX2,RAPGEF6,ZNF638,KIAA1958,RABL2A,PADI2,NEGR1,CELF5,KCNQ3,STMN1,LSAMP,MBNL1,GNG2,ZNF426,SDK2,EPDR1,PTPRB,ZFP1,UHRF1BP1L,RUNDC3B,SSBP2,BCL2L13,TSPAN11,ZNF781,ZNF138,URM1,WNK2" MicroRNA hsa-miR-519e:PITA hsa-miR-519e:PITA_TOP PITA 2.09E-16 1.17E-12 4.41E-16 4.06E-15 35 176 "ARHGAP20,QKI,SLC35F1,CLOCK,CS,DOCK4,ALKBH8,NR1D2,PDCD6IP,EPB41,RAB30,TOX2,MAT2A,MYO5A,MYO6,RETREG2,PPP2R5E,RIPOR1,CYB561D1,PEAR1,HSPA4L,SOX11,ITPRID2,SSTR1,SYT1,SYNE1,FRYL,DICER1,LYPD6,DPYSL5,ZFAND5,SMARCAD1,RTN4,KAT6A,DPF3" MicroRNA hsa-miR-554:mirSVR_highEffct hsa-miR-554:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-16 1.17E-12 4.41E-16 4.06E-15 50 351 "CLK4,ABCD2,AMPD3,LRFN1,CDC42BPA,TTLL9,DST,THSD7A,MTMR7,TPP1,HEPH,EIF1,ZNF589,ATP13A4,PDLIM5,PPARGC1A,GLUL,KDM2B,PSIP1,SLC2A6,HSF2,RBPJ,IL6ST,INPP5B,MYO9A,GPR85,PIK3R1,MINDY2,PTK2,FAT4,RGS12,TNFRSF19,ZFP30,CNKSR2,NLGN1,SEC31A,PREX2,ARHGEF40,CCDC88A,RCOR3,KIF13A,SNRPN,TEX2,NXT2,STAU1,FAM200B,ACTR6,TMPO,ADAMTS9,URM1" MicroRNA hsa-miR-296-3p:PITA hsa-miR-296-3p:PITA_TOP PITA 2.31E-16 1.29E-12 4.88E-16 4.49E-15 26 93 "FMNL2,CADPS,ATP2A2,JAZF1,FOXN3,SOCS6,NRXN3,DCAF8,JAKMIP2,PAN3,AGAP2,TCERG1,KITLG,ANKRD16,STRN3,PTCH1,RBBP6,MSANTD2,FBXW7,SEMA6D,ERC1,POGZ,NKAIN2,SYN1,TCF12,TBC1D15" MicroRNA hsa-miR-4793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-16 1.32E-12 4.99E-16 4.59E-15 55 418 "XKR4,SLC24A4,HACE1,KIAA1324,WDR35,TXNDC16,AK2,PHF12,AQP6,CDC14B,ZNF555,SLC16A4,ZNF445,NRXN3,CRY2,SUSD5,SOCS5,UBXN2A,TMEM170A,DNAL1,MTX3,EPB41,KATNAL1,ATP13A4,ANKFY1,FUT9,ZNF234,DBF4,GPR75,KIAA1958,KCNN3,CHST6,ZC3H12B,SLC11A2,GPR137C,STK32A,TMEM145,ZNF844,KLHL11,ALG9,ATAT1,SEPHS1,ANKRD36,ZHX3,MCF2L2,ARL10,PPIL6,SSBP2,ZNF610,UBC,USP1,SLC30A4,TRIM16L,HNRNPA3,GAN" MicroRNA hsa-miR-5096:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-16 1.37E-12 5.17E-16 4.76E-15 46 302 "XKR4,PCDH19,TAOK1,TRMT9B,C6orf89,ARSE,CADPS,ZNF445,FOXN3,AKAP6,SEC31B,ANKRD44,CSNK1E,LONRF1,KIAA0586,DBT,JAKMIP2,WDPCP,FOXF2,TRMO,MPP6,TRAF3IP2,TNRC6A,PRRC2B,PTPRT,RNF165,DDX19B,IL6R,SLC6A17,MINDY2,ZNF793,C12orf49,PGBD4,PTGR2,FNIP1,SH3BP2,ALG1,AGTPBP1,SATB2,CLDND1,ZNF708,ZNF70,SLC38A1,PHTF2,MSRB3,GAN" MicroRNA hsa-miR-515-3p:PITA hsa-miR-515-3p:PITA_TOP PITA 2.51E-16 1.41E-12 5.30E-16 4.88E-15 35 177 "ARHGAP20,QKI,SLC35F1,CLOCK,CS,DOCK4,ALKBH8,NR1D2,PDCD6IP,EPB41,RAB30,TOX2,MAT2A,MYO5A,MYO6,RETREG2,PPP2R5E,RIPOR1,CYB561D1,PEAR1,HSPA4L,SOX11,ITPRID2,SSTR1,SYT1,SYNE1,FRYL,DICER1,LYPD6,DPYSL5,ZFAND5,SMARCAD1,RTN4,KAT6A,DPF3" MicroRNA hsa-miR-6086:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-16 1.44E-12 5.42E-16 4.99E-15 64 545 "ABCF1,NDRG3,SLC24A4,HECW2,HACE1,ZNF578,TRMT9B,AQP6,CDC14B,DOCK11,PTBP2,CBS,CBFA2T2,ARHGEF2,CDR1,CCPG1,NRXN3,ZNF385A,GAPVD1,TBC1D5,DNAL1,DBT,MTX3,DNAH9,MRO,RASA4,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,FAM198B,ZNF585B,SCML2,FECH,DISC1,CRCP,GNG4,LILRA2,KAT7,IGF1,TJAP1,IBA57,MXI1,PPP3CC,NCR3LG1,CEP97,RBBP8,ALG9,GSTCD,PTGR2,NCBP3,FNIP1,ATF7IP,FNBP1,CDK19,FAM208A,TPCN2,BHLHB9,LAT2,CLDND1,ZNF17,ZNF70,EVI5" MicroRNA hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 2.60E-16 1.46E-12 5.48E-16 5.05E-15 58 460 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,HDAC4,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,EGFR,IRAK4,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 2.60E-16 1.46E-12 5.48E-16 5.05E-15 58 460 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,MBNL2,IRAK4,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,TRPS1,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-5001-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-16 1.55E-12 5.83E-16 5.36E-15 36 188 "XKR4,MTA3,TAOK1,ARSE,GYG2,IGLON5,TOGARAM2,NRG2,CPS1,PITPNM3,KIAA0408,BOC,YTHDC1,KRBA2,EDN1,RGS17,EPB41,MSANTD4,NXPH3,NKD1,KPNA5,LIMS1,GPR155,FITM2,STK32A,PNMA8A,STUM,HSPA4L,SP2,ZNF621,GPRIN3,PCDHA6,ARL10,ERCC6L2,PARD3,AGMO" MicroRNA hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.87E-16 1.61E-12 6.05E-16 5.57E-15 58 461 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,MBNL2,IRAK4,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,TRPS1,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-181c-5p:Functional MTI Functional MTI miRTarbase 2.88E-16 1.61E-12 6.07E-16 5.59E-15 45 291 "NDRG2,MTUS1,HECW2,HFM1,ARRB2,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,MTX3,DPYSL2,FSD1L,FAM13A,STX2,IQCG,ZDHHC15,KIT,IPO5,NCOA7,BLOC1S2,PPP2R5E,ZNF844,UBR7,PBRM1,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,BTBD3,CPEB4,ZNF667,ZNF415,TMCC1,UNC5B,PRRC2C,TRIM2,SLC35G2,SIRT1,TUBB2A,ZNF781,ZNF23,SPIRE1,EMSY" MicroRNA "GGCCAGT,MIR-193A:MSigDB" "GGCCAGT,MIR-193A:MSigDB" MSigDB 3.12E-16 1.75E-12 6.55E-16 6.03E-15 25 86 "KCNH8,CDK10,STX16,CALB1,CAPN3,RUNX1T1,TAOK2,ZC3H11A,E2F6,ERBB4,ETV1,ANKFY1,KIT,LAMP2,CAMK2N2,STMN1,MKLN1,MMP16,MYCN,NOVA1,SPATA7,ZHX3,CAMTA1,LRRC8A,NAV3" MicroRNA "GGCCAGT,MIR-193B:MSigDB" "GGCCAGT,MIR-193B:MSigDB" MSigDB 3.12E-16 1.75E-12 6.55E-16 6.03E-15 25 86 "KCNH8,CDK10,STX16,CALB1,CAPN3,RUNX1T1,TAOK2,ZC3H11A,E2F6,ERBB4,ETV1,ANKFY1,KIT,LAMP2,CAMK2N2,STMN1,MKLN1,MMP16,MYCN,NOVA1,SPATA7,ZHX3,CAMTA1,LRRC8A,NAV3" MicroRNA hsa-miR-486-5p:PITA hsa-miR-486-5p:PITA_TOP PITA 3.15E-16 1.76E-12 6.61E-16 6.08E-15 30 129 "KCNH8,DYNLL1,LYPD1,GRIN3A,DYNC1I1,FGF13,CSPG5,GABRB3,CIT,MIER3,MYLK2,IGF1,CYP27C1,MARK1,PIK3R1,TRHDE,RGS4,ST6GALNAC6,NLGN1,RCOR3,PDZRN3,ST5,PRRC2C,TCF4,PUM2,KAT6B,NR2C2,FLRT2,SMARCAD1,HNRNPA3" MicroRNA hsa-miR-648:PITA hsa-miR-648:PITA_TOP PITA 3.19E-16 1.78E-12 6.69E-16 6.16E-15 34 168 "MAP4K3,BCL7A,CALM1,PTBP2,EVI5L,HECTD1,SLC35F1,PUM1,HDAC4,CPEB2,DLC1,FUT9,GPD1,GRIA2,BACH2,NEGR1,MARK1,MAT2A,MBNL1,MEIS1,AFDN,ROBO2,ARX,CPEB4,MBD5,DDN,POGZ,SATB2,LRRC8A,FLRT2,TMEM237,EMSY,PDSS2,JMJD1C" MicroRNA hsa-miR-193a-3p:TargetScan hsa-miR-193a-3p TargetScan 3.51E-16 1.96E-12 7.36E-16 6.78E-15 38 211 "GPR146,DST,FUBP1,DDR1,CALB1,CALM1,RUNX1T1,SEC31B,CLOCK,FAM131B,DBN1,E2F6,PLXNC1,ERBB4,ETV1,ANKFY1,PPARGC1A,GNAO1,ATOH8,KIT,LAMP2,MMP16,MYCN,NOVA1,MAPK10,CNNM2,FAT4,MSANTD2,RFX3,CSRNP3,CXXC4,FAIM2,RGL1,LRRC8A,DOK6,GDPD5,NAV3,ADAMTSL3" MicroRNA hsa-miR-193b-3p:TargetScan hsa-miR-193b-3p TargetScan 3.51E-16 1.96E-12 7.36E-16 6.78E-15 38 211 "GPR146,DST,FUBP1,DDR1,CALB1,CALM1,RUNX1T1,SEC31B,CLOCK,FAM131B,DBN1,E2F6,PLXNC1,ERBB4,ETV1,ANKFY1,PPARGC1A,GNAO1,ATOH8,KIT,LAMP2,MMP16,MYCN,NOVA1,MAPK10,CNNM2,FAT4,MSANTD2,RFX3,CSRNP3,CXXC4,FAIM2,RGL1,LRRC8A,DOK6,GDPD5,NAV3,ADAMTSL3" MicroRNA hsa-miR-580-3p:Functional MTI Functional MTI miRTarbase 3.60E-16 2.01E-12 7.55E-16 6.95E-15 31 139 "RNF157,AK2,SEMA7A,TNRC6C,BACH1,AKAP5,TBPL1,CLOCK,RNF14,RUBCN,GUCD1,AMOTL2,PCYOX1,FAM49B,HRASLS5,GPR75,ZNF678,LAMA2,MBNL1,XRRA1,PRKAB2,SLC25A36,SETD5,ARMH4,FAM161B,FNBP1,ZNF621,POGZ,ZMAT3,BCL2L13,MTCH1" MicroRNA hsa-miR-335-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-16 2.02E-12 7.56E-16 6.96E-15 46 305 "XKR4,RNF150,PCDH19,MARCH4,CADPS,CACNA1A,C1orf52,FOXN3,ENTPD4,ANKRD44,VCAN,APPL1,PUM1,RIMS2,FAM107B,TMTC1,YAF2,TENM1,TAOK3,FOXF2,TMEM107,SULT1C4,KCNMB4,GNAL,PRRC2B,RNF165,NEGR1,IL6R,KCNN3,MBNL1,GLIPR1L2,PAX6,ZNF426,SH3KBP1,PPARA,SH3TC2,ZMAT4,GTDC1,FAM126B,FAM208A,KLHL4,CLDND1,ZNF24,KCNT2,ZNF225,SLC38A1" MicroRNA hsa-miR-6742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-16 2.02E-12 7.56E-16 6.96E-15 46 305 "AS3MT,TXNDC16,AQP6,PRX,SLC4A4,ZNF555,CBS,DIS3L,CSNK1E,SOCS5,PITPNM3,ZBTB24,MTX3,FEM1B,RGS17,SLC43A2,IGSF6,AMOTL2,KDM2B,LILRA2,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,STK32A,ZSCAN2,CEP97,PRRT2,GTDC1,STX1B,FAM192A,BDP1,MCF2L2,SSTR2,ALG1,ARL10,CBX5,PARD3,SSBP2,ZNF610,USP1,KLC2,SLC30A4,RNF170,GAN" MicroRNA hsa-miR-423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-16 2.07E-12 7.75E-16 7.13E-15 49 343 "AK2,IGDCC4,ARHGDIA,ARRB2,KIF1A,MTMR3,USP6,ARHGEF2,EVI5L,SRSF11,TMEM184B,SLITRK5,ARHGAP32,SPATA2,RPS6KL1,ABCC5,EIF1,EPB41,BRSK1,SEPT9,AHDC1,GLUL,POLL,PRRC2B,TDRKH,RNF165,KCNK3,MMP17,NFIX,PDPK1,PFKFB3,ZNF655,PKM,KCTD15,MTRF1L,SALL1,COPZ1,SLC2A5,LIMS2,TEX2,NFASC,SEPT8,DIP2A,PLCB1,NSD1,WBP2,RPL7L1,POLR3H,URM1" MicroRNA hsa-miR-4319:mirSVR_highEffct hsa-miR-4319:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.73E-16 2.09E-12 7.81E-16 7.19E-15 56 436 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,ARNTL,CDK13,USP2,P2RX6,SULT4A1,LY86,SLC4A8,HINFP,IST1,SPEG,SEMA4D,CGREF1,KIAA1841,LOXL3,RABL2A,AGBL5,MSL1,ZNF546,KCNN2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,TMLHE,COPZ1,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,DIP2A,C18orf54,MTMR14,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,SEMA3B,EPM2A,TIGD6,IFT88" MicroRNA hsa-miR-1202:PITA hsa-miR-1202:PITA_TOP PITA 3.94E-16 2.21E-12 8.26E-16 7.60E-15 33 159 "PDZD4,MAP4K3,BCL7A,JAZF1,TAOK2,NDST3,ARHGEF4,PPP6R2,POM121,DMTF1,DNAJB6,PHC2,ETV1,TAOK3,PCDH17,DCLK2,MYO5A,PDE1B,RETREG1,PRKCB,PTCH1,ZFHX4,FNDC3A,BTBD3,CPEB4,RGL1,PUM2,RELL2,RIMBP2,CSMD1,TMEM237,LAMP5,HNRNPA3" MicroRNA hsa-miR-1343-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-16 2.25E-12 8.43E-16 7.76E-15 39 223 "AS3MT,PRX,ARHGDIA,SLC4A4,CBS,CCNT1,DIS3L,CSNK1E,ZBTB24,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,UFM1,KDM2B,LILRA2,KPNA5,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,AMBRA1,BDP1,ALG1,AGTPBP1,ARL10,CBX5,PARD3,WBP2,SSBP2,KLC2,RNF170" MicroRNA hsa-miR-6783-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-16 2.25E-12 8.43E-16 7.76E-15 39 223 "AS3MT,PRX,ARHGDIA,SLC4A4,CBS,CCNT1,DIS3L,CSNK1E,ZBTB24,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,UFM1,KDM2B,LILRA2,KPNA5,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,AMBRA1,BDP1,ALG1,AGTPBP1,ARL10,CBX5,PARD3,WBP2,SSBP2,KLC2,RNF170" MicroRNA hsa-miR-1321:PITA hsa-miR-1321:PITA_TOP PITA 4.10E-16 2.29E-12 8.57E-16 7.89E-15 37 201 "ASIC1,KLHL13,CAMK2G,RUNX1T1,DLGAP2,PICK1,AIF1L,DBN1,DNM1,SEZ6L2,NRN1,AGAP2,RNF165,LRRTM1,MAT2A,NFIX,NOVA2,PURG,PMP22,RETREG2,PTK2,PTPRO,RAP1GDS1,PRRT2,ATXN2,COPZ1,WDR47,FAM214B,SOX11,SS18,CBX5,SSBP2,UBE3A,MEIS3,RNF103,KCNAB1,KAT6A" MicroRNA hsa-miR-99a:mirSVR_lowEffct hsa-miR-99a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.12E-16 2.31E-12 8.62E-16 7.94E-15 38 212 "ZFAT,ARNTL,SYNJ1,MTMR3,MTMR2,LURAP1,UBXN2A,DBI,ALKBH8,PLPPR4,SUGP2,IP6K2,NOP56,MEGF10,ERAP1,ALDH1L1,ADAM28,C2orf72,INSM1,MYO7A,PCSK1,PURG,ING3,HYDIN,PTPRN2,CYB561D1,ATP8B4,FBXO11,SLC14A1,MYO16,KDM4C,TSPYL2,ST5,ANKRD28,UBE3A,VLDLR,GAL3ST3,URM1" MicroRNA hsa-miR-1291:mirSVR_highEffct hsa-miR-1291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.68E-16 2.62E-12 9.79E-16 9.01E-15 51 371 "GALNT13,MTUS1,OGT,PLA2G4C,ADAM23,SYNJ1,CACNA1G,RAB28,SEC24C,GIT2,DBN1,NYAP1,DYNC1I1,YAF2,SLC9B2,SPSB4,ZNF638,GRIA2,LINGO1,ATXN2L,VSIG4,ELOVL5,ZDHHC15,CPT1C,SCIN,ITGA7,NF1,VWA2,SLC11A2,NUCB2,PNMA3,SCHIP1,PILRA,TMEM260,ERI2,CARF,GSTCD,EPHA10,LRRK2,FAM214B,ATF7IP,SLC22A4,ABTB1,OGDHL,SYNE1,TIAM1,ERCC6L2,RGMB,RPL7L1,EMSY,PDSS2" MicroRNA hsa-miR-140-3p:Functional MTI Functional MTI miRTarbase 4.71E-16 2.64E-12 9.84E-16 9.06E-15 39 224 "SLC24A4,KSR1,CD38,CRY2,KIAA0040,GAPVD1,PITPNC1,POM121,CHRDL1,MAMLD1,EPB41,TUBA1B,FDFT1,PCYOX1,GGT7,NCKAP1L,KIF5A,LAMP2,MYO6,NFYA,PLCL1,PSAT1,NWD1,SETD5,CLIP1,STUM,KIF21A,SLC2A5,ZNF423,NFASC,SS18,DNAJC9,ANKRD12,THRA,UBTF,TBC1D15,CLDND1,SLC30A3,SPATA13" MicroRNA "GGGCATT,MIR-365:MSigDB" "GGGCATT,MIR-365:MSigDB" MSigDB 4.83E-16 2.70E-12 1.01E-15 9.28E-15 27 104 "PHF12,ARRB2,SYNJ1,KALRN,SOCS5,HDAC9,HDAC4,TIAM2,ETV1,ADAMTS6,HMGCR,KCNH2,LAMP2,PAX6,TRHDE,ING3,PPP5C,GRAMD1C,SNRK,REV3L,SGK1,WDR37,USP33,ANKRD28,SATB2,SGK3,RICTOR" MicroRNA hsa-miR-556-5p:PITA hsa-miR-556-5p:PITA_TOP PITA 4.94E-16 2.77E-12 1.03E-15 9.50E-15 30 131 "RUNX1T1,QKI,RIMS4,DOCK4,DNAJB6,PAN3,MN1,MXI1,NEXMIF,MYT1,ZNF827,STRN3,MAPK3,TMEM260,RDX,NUDT11,RXRA,CPEB3,SLC4A3,BTBD3,FAM126B,SOX11,TBL1X,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,TIAM1,WNK3" MicroRNA hsa-miR-520e:Functional MTI Functional MTI miRTarbase 5.14E-16 2.88E-12 1.07E-15 9.88E-15 57 453 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,MAP4K4,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,EGFR,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-6720-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-16 2.93E-12 1.09E-15 1.01E-14 62 524 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,ARSE,GPR146,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,MTX3,EBI3,IRAK4,EPB41,ANKFY1,TRMO,ZNF234,CRCP,GPR75,GPT2,PARD3B,DDX19B,AGBL5,SLC6A17,CHST6,ZC3H12B,SLC11A2,MTRF1L,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ZNF331,SALL1,SGK1,SEPHS1,RADIL,FAM126B,MCF2L2,SSTR2,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-1207-5p:PITA hsa-miR-1207-5p:PITA_TOP PITA 5.60E-16 3.13E-12 1.17E-15 1.08E-14 34 171 "CACNA2D1,PLEKHB1,AKAP5,ZNF385A,CPEB2,ABCC5,CELSR3,APH1A,TMEM132E,PPP1R1B,HPCAL4,SYT3,CPLX2,STMN2,IGF1,CAMK2N2,RETREG2,EPB41L4B,TMEM145,GTDC1,SETD5,FBXW7,SCN2B,TMCC1,SYP,ASTN2,CLASP1,PUM2,CBX5,TRPS1,GAL3ST3,NAV3,SLC17A7,ADAMTS10" MicroRNA hsa-miR-573:PITA hsa-miR-573:PITA_TOP PITA 5.69E-16 3.18E-12 1.19E-15 1.09E-14 38 214 "PKP4,SPAG9,CDH2,FOXN3,CLTC,QKI,DPH1,MBNL2,PAN3,CHL1,GUCY1A1,DDX19B,MIER3,SMAP1,IGF1,KCNN2,KIT,PTPRD,PID1,TMEM255A,ALG9,ATP8B4,SEMA6D,SEPHS1,CPEB4,FAM126B,ERBIN,NECAB1,SYT1,SATB2,KAT6B,FAM155A,POLR3H,PRDM10,WNK3,HNRNPA3,JMJD1C,RNF146" MicroRNA "GAGACTG,MIR-452:MSigDB" "GAGACTG,MIR-452:MSigDB" MSigDB 5.70E-16 3.19E-12 1.19E-15 1.09E-14 25 88 "AXIN2,OGT,DPP10,DYNLL1,DOCK11,DCLK1,CCPG1,ABCC5,SYNCRIP,FOXO3,CELF1,PCDH17,CBX1,ITPKA,MEIS1,OCRL,SLC25A23,PLXNB1,EPB41L4B,BCAS3,GTDC1,FBXO11,TCF4,TCF12,ZIC1" MicroRNA hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 6.26E-16 3.50E-12 1.30E-15 1.20E-14 57 455 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,EIF4G1,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,SIRT1,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-4252:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-16 3.50E-12 1.30E-15 1.20E-14 57 455 "CLK4,ELFN2,SLC24A4,HECW2,HACE1,TBC1D14,TXNDC16,TAOK1,PHF12,AQP6,CDC14B,ZNF555,SLC16A4,CBFA2T2,NRXN3,UBXN2A,TMEM170A,DNAL1,MTX3,MRNIP,EPB41,ATP13A4,CELF1,ZNF234,GPR75,TNRC6A,DDX19B,ZNF491,ZNF546,IL6ST,IBA57,CHST6,ZC3H12B,MINDY2,STK32A,TMEM145,ZNF844,TRIM68,ALG9,FBXW7,ATAT1,FNBP1,LHPP,SSTR2,USP22,ARL10,CBX5,RUNDC3B,PPIL6,SSBP2,ZNF610,RPL7L1,LAT2,ZNF70,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-23b-3p:Functional MTI Functional MTI miRTarbase 6.32E-16 3.54E-12 1.32E-15 1.21E-14 47 322 "ABCF1,USP31,SORCS2,ZNF578,ATP1A1,BCS1L,SOCS6,HAPLN1,VCAN,DOCK4,TMEM170A,PDCD6IP,FSD1L,PTK2B,RACK1,CELF1,AP4B1,MPP6,ARFIP1,ADAM28,TNRC6A,ZIC5,MAP4,BLOC1S2,PIK3R1,ZNF426,KANSL1,PRKACB,ZIK1,ACSS3,CYB561D1,PCMTD2,SEMA6D,SBF1,FNIP1,CPEB3,ATF7IP,ERBIN,DNMBP,ZEB1,NSD1,SIRT1,RPL7L1,XPO1,ZNF138,DHX33,JMJD1C" MicroRNA hsa-miR-6881-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.41E-16 3.59E-12 1.34E-15 1.23E-14 39 226 "TNRC6C,LDLRAD4,RUNX1T1,LRRFIP1,DIS3L,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,IP6K1,SPATA2,TMCC2,DPYSL2,RCAN1,ANKMY1,REEP2,SCML2,HHIPL1,RAPGEF6,ZNF638,GRM8,CYP27C1,SYTL4,MBNL1,GNG2,POLG,PRKCB,PIGG,ZNF844,ELP2,ZFP30,MYO18A,SLC6A8,SEPT8,VPS13A,UGT8,AMZ1,FRMD6" MicroRNA hsa-miR-335-5p:TargetScan hsa-miR-335-5p TargetScan 6.67E-16 3.73E-12 1.39E-15 1.28E-14 38 215 "NCKAP5,ELFN2,CDK13,CERS5,ARHGEF2,CLOCK,OSBPL3,FAM131B,ARHGAP32,FAM107B,ERBB4,CORO2B,HPCAL4,CAMKK2,GLYR1,GPR75,KDM2B,KAT7,ITPKB,LSAMP,MAPK10,FITM2,CNNM2,APTX,PTPRB,ERI2,RPE,KDM4C,ITGB3BP,DOK6,RPRM,POLR3H,EVI5,PRDM10,RGS7BP,FZD3,NETO2,GAN" MicroRNA hsa-miR-220c:PITA hsa-miR-220c:PITA_TOP PITA 6.74E-16 3.77E-12 1.40E-15 1.29E-14 37 204 "CDC14B,SEMA4G,ATP2A2,CACNA1A,CAMK2G,CFL2,SOCS6,CRY2,NCOR2,SLITRK5,PUM1,RUSC2,NR1D2,CPEB2,EDIL3,APH1A,PAN3,AGAP3,CPLX2,GNAO1,ADAMTS6,MIER3,CHIC1,NOVA2,PTCH1,RBBP6,RIC8B,ZFHX4,PPM1E,SNAP25,ZHX3,POGZ,SS18,ARHGEF9,FBXW11,MAP3K12,KAT6A" MicroRNA hsa-miR-1224-5p:TargetScan hsa-miR-1224-5p TargetScan 7.11E-16 3.98E-12 1.48E-15 1.36E-14 32 152 "C3orf14,ELFN2,ADORA1,PTCHD1,RUNX1T1,PRC1,RIMS4,PLCXD3,GRIN3A,FGF1,FGFR1,ANKFY1,MMADHC,GPD1,AGFG1,KCNK3,IPO5,CHIC1,MMP16,BLOC1S2,NOVA1,GPR137C,PKD1,MAPK4,MAPK10,PRRT2,GTDC1,FIGN,RPE,SATB1,CBX5,PRRT4" MicroRNA hsa-miR-585:mirSVR_lowEffct hsa-miR-585:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.41E-16 4.15E-12 1.54E-15 1.42E-14 35 183 "HACE1,CC2D2A,PITPNM2,UPRT,KALRN,ANKRD44,CSF1R,LYPD1,PHC2,CELSR3,EMX2,ZNF589,FGF11,FLYWCH1,GPR12,VSIG4,SYNPO,OPRL1,MTRF1L,SLC25A36,STK32B,ATXN2,FAM214B,CDK5RAP2,DBNDD2,SLC37A2,KLHL4,TRIO,LINC00689,GUSBP1,LYPD6,EML6,ZFAND5,RTN4,UBE3B" MicroRNA hsa-miR-6821-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-16 4.17E-12 1.55E-15 1.42E-14 44 286 "AS3MT,TAOK1,PHF12,VXN,STOML1,ENTPD4,MYADM,DBT,CHRDL1,RGS17,SEC24B,SRCAP,HAS2,DDX19B,C2orf72,IL6R,KCNN1,KCNN3,MAN2A2,MBNL1,CHST6,P2RX7,TMOD2,PIK3C2A,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,HSPA4L,NUBPL,ZNF430,ANKRD36,FAM126B,ZBTB43,SSTR2,STAC2,KLHL7,ZNF34,USP1,ZNF708,GAN,SPATA13" MicroRNA "TCTGGAC,MIR-198:MSigDB" "TCTGGAC,MIR-198:MSigDB" MSigDB 7.50E-16 4.20E-12 1.56E-15 1.43E-14 24 81 "PCDH19,PHF12,BCL7A,CAPN3,STOML1,QKI,CNR1,LETMD1,NCOR2,SLITRK5,APH1A,GLYR1,KDM2B,BTN2A1,TOX2,KCND1,MSR1,NNAT,FIGN,ZNF821,POGZ,TCEA1,PUM2,NR2C2" MicroRNA hsa-miR-134:PITA hsa-miR-134:PITA_TOP PITA 7.70E-16 4.31E-12 1.60E-15 1.47E-14 30 133 "ASIC1,AMPH,NUMB,SLC4A4,ZNF385A,SH2B1,CSNK1G3,ARHGEF4,ARMCX2,CPEB2,PAN3,SRRM4,MSTN,GNAO1,PRRC2B,KAT7,HAS2,MAT2A,MBNL1,MYCN,NRCAM,MTCL1,ADGRL3,KAT6B,SSBP2,ZNF711,TRIM9,SMARCAD1,SLC30A4,HNRNPA3" MicroRNA "ACACTAC,MIR-142-3P:MSigDB" "ACACTAC,MIR-142-3P:MSigDB" MSigDB 8.31E-16 4.65E-12 1.72E-15 1.59E-14 29 124 "FMNL2,TAOK1,APC,ARNTL,ATP2A2,BACH1,CFL2,HECTD1,PUM1,CPEB2,ACSL4,SUCO,AFF2,KAT7,PSIP1,BACH2,AFF1,PDE4B,STRN3,SGK1,FNDC3A,BTBD7,ATF7IP,SOX11,STAU1,SYPL1,TRPS1,RICTOR,XPO1" MicroRNA hsa-miR-188-3p:PITA hsa-miR-188-3p:PITA_TOP PITA 8.71E-16 4.87E-12 1.81E-15 1.66E-14 39 228 "ALCAM,CHRD,ZNF583,THSD7A,PTBP2,CAMK2G,ZMYM4,SLIT2,CLTC,COL4A5,KCTD8,C2CD2L,PHC2,NRN1,CLVS1,SUCO,PCDH17,TNRC6A,ZNF181,PPM1L,NEXMIF,ZC3H12B,ZDHHC8,STRN3,IRX1,MAPK4,PSD,PTPRD,NCBP3,RCOR3,ASTN2,ANKRD12,RPGRIP1L,SSBP2,FAM155A,ZNF781,ZNF711,MSRB3,ST8SIA2" MicroRNA hsa-miR-504-5p.1:TargetScan hsa-miR-504-5p.1 TargetScan 8.84E-16 4.94E-12 1.83E-15 1.69E-14 35 184 "PCDH19,KCTD16,PTBP2,RUNX1T1,LRRFIP1,DLGAP2,IGLON5,CNTFR,ARMC8,NCOR2,PLXNA4,GRIN3A,RCAN2,EYA1,HPCAL4,FLT1,MMADHC,KCNMB4,KCNK3,KPNA5,SAMD14,NOVA2,PKD1,CYB561D1,RORB,EPHA10,RPL15,CSRNP3,MAPKBP1,ANKRD12,KIAA0930,NSD1,ASXL3,NR2C2,KLC2" MicroRNA hsa-miR-5692b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.71E-16 5.43E-12 2.01E-15 1.85E-14 34 174 "ABCF1,XKR4,ADD2,TAOK1,STX16,NRP2,CA8,ABCG2,PITPNC1,TMTC1,ACSL4,ZBED3,MPP6,TNRC6A,LUZP2,BACH2,MIER3,ZIC5,AFF1,OCRL,EPDR1,MAPK7,ENOX1,UBR7,HSPA4L,BTBD3,SYP,TACC1,TRIM2,SIK3,TRPS1,UBE3A,ZFP37,SLC38A1" MicroRNA hsa-miR-5692c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.71E-16 5.43E-12 2.01E-15 1.85E-14 34 174 "ABCF1,XKR4,ADD2,TAOK1,STX16,NRP2,CA8,ABCG2,PITPNC1,TMTC1,ACSL4,ZBED3,MPP6,TNRC6A,LUZP2,BACH2,MIER3,ZIC5,AFF1,OCRL,EPDR1,MAPK7,ENOX1,UBR7,HSPA4L,BTBD3,SYP,TACC1,TRIM2,SIK3,TRPS1,UBE3A,ZFP37,SLC38A1" MicroRNA hsa-miR-7847-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.84E-16 5.51E-12 2.04E-15 1.88E-14 46 313 "ABCF1,ADCY5,HACE1,PTBP2,CBS,CSF1,GAPVD1,DNAL1,ZC3H11A,SGSM2,MRO,FGFR1,CAMKK2,NEURL4,CSDC2,LILRA2,SHISA6,IGF1,MAP2,MAT2A,MXI1,KSR2,GPR137C,TMOD2,PKM,PLEC,PLXNB1,NCR3LG1,RAP1GDS1,PGBD4,KIAA0895L,NCBP3,MYO18A,KIF13A,SOX11,PEG10,DBNDD2,CDK19,AGTPBP1,ATMIN,WBP2,LAT2,WRN,ZNF17,EVI5,PARP11" MicroRNA hsa-miR-6845-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.98E-16 5.58E-12 2.07E-15 1.90E-14 42 264 "PWWP2A,MTA3,SEMA7A,ARHGDIA,PTCH2,ATP1A3,LDLRAD4,RUNX1T1,CBARP,CSNK1G3,PITPNM3,UBXN2A,CYBB,GAPVD1,EMX2,SLC43A2,GALC,DISC1,GATM,GPT2,C2CD4C,LSAMP,NFIX,NFYA,PALM,SNRK,ATXN7,FAM214B,ZFP1,ZNF667,ZNF415,UNC5B,MPRIP,DIP2A,USP22,SZT2,CRTC1,SMUG1,ZNF23,ZNF138,HNRNPA3,JPH3" MicroRNA hsa-miR-1273e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-15 5.70E-12 2.11E-15 1.94E-14 57 460 "ABCF1,NDRG3,HACE1,SORCS2,OSBPL8,LCORL,APAF1,TNRC6C,AQP6,IGDCC4,PTBP2,CBS,SLC16A4,SUMF2,DCAF4,MYADM,SCRN1,DNAL1,DNAH9,HEYL,MRO,RASA4,ANKMY1,FAM198B,ZNF585B,DLC1,ZNF589,GABRA3,GNG4,ZNF491,MXI1,NCAM2,PPP2R5E,PRKACB,ZNF844,CEP97,RBBP8,KLHDC8A,ALG9,ROBO1,ELP2,SNX22,ZNF354C,TRAPPC13,PEAR1,SEPHS1,SLC8A1,MCF2L2,ANKRD12,TAL1,RASD2,ZKSCAN5,TBC1D15,LAT2,ZNF74,CADM2,PARP11" MicroRNA hsa-miR-486-3p:PITA hsa-miR-486-3p:PITA_TOP PITA 1.03E-15 5.78E-12 2.14E-15 1.97E-14 33 164 "OGT,FAM131A,MARK4,CHRD,CNTFR,CLIP3,RIMS4,CPEB2,EIF4G1,BAIAP2,AGAP3,FLNC,SYT3,AHDC1,TTBK1,LOXL3,CIT,ITPKB,CAMK2N2,MAPT,NEFH,NFIX,EPB41L4B,SH3KBP1,PKIA,PLCB1,SYP,TCF12,RELL2,SSBP2,RPRM,TMEM178A,SLC17A7" MicroRNA hsa-miR-6851-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-15 5.86E-12 2.17E-15 2.00E-14 48 339 "ABCF1,HACE1,DOCK11,DDR1,PTBP2,CBS,PITPNM3,GAPVD1,DNAL1,DUSP9,APH1A,MRO,FGFR1,LILRA2,SHISA6,IGF1,SLC6A17,MXI1,TBC1D25,PKM,SMOX,PPARA,CNNM2,NCR3LG1,MTMR10,CEP97,RAP1GDS1,PGBD4,NCBP3,AMBRA1,SLC2A5,EPN2,KIF13A,SOX11,UNC5B,CDK19,DDN,AGTPBP1,SLC19A3,WBP2,SSBP2,BCL2L13,LAT2,ZNF17,SMARCAD1,EVI5,CIAPIN1,PARP11" MicroRNA hsa-miR-505-3p.1:TargetScan hsa-miR-505-3p.1 TargetScan 1.07E-15 5.98E-12 2.21E-15 2.03E-14 38 218 "HECW2,APBB2,CACNB4,C1orf52,NUMBL,FOXN3,MAGED1,NRG2,CCDC144A,KIAA0408,CPEB2,DNM1L,ANKFY1,MSANTD4,GABRG1,CYP46A1,GLYR1,FUT10,NEGR1,C2orf72,IL6ST,KIT,LRP1B,MEIS1,MEIS2,MYCN,HNRNPM,NOVA1,OPA1,SCHIP1,CNNM2,CEP97,FAM192A,EPN2,EPC1,FAM126B,ELOVL4,CBX5" MicroRNA hsa-miR-623:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-15 6.07E-12 2.24E-15 2.06E-14 40 241 "AS3MT,XKR4,SORCS2,AK2,SPOP,AQP6,ASGR1,BCL7A,BID,MYRF,CACNA1A,LURAP1,CAMK2G,SLC16A4,IPCEF1,SPATA2,CHRDL1,FEM1B,AMOTL2,SRCAP,LILRA2,TPPP,PTPRT,PADI2,EID2B,KLHL23,LSAMP,MEIS1,NPTX1,KANSL1,MARCH1,SH3TC2,DPF2,RORB,ELP2,MYO18A,ZBTB43,PRRC2C,ZDHHC20,DPF3" MicroRNA hsa-miR-4311:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-15 6.12E-12 2.26E-15 2.08E-14 36 196 "TRMT9B,CDC42BPA,CALM1,AKAP6,TM9SF4,SPATA2,FAM107B,CHRDL1,ZNF391,SARAF,HRASLS5,SYT17,SRCAP,PPARGC1A,RNPS1,DCLK2,GRB10,PTPRT,SYNPO,MEIS1,CNOT4,GPR137C,ZNF827,GPR173,PDZRN4,PTPRN2,CEP97,MORC4,CCDC88A,SLC19A3,SLC44A1,KAT6B,TUBB2A,WRN,ZIC2,SIGLEC10" MicroRNA hsa-miR-1206:PITA hsa-miR-1206:PITA_TOP PITA 1.16E-15 6.51E-12 2.40E-15 2.21E-14 34 175 "TAOK1,ALCAM,USP37,TMEFF1,USP6,DGKI,KCNAB3,QKI,SOCS5,CDON,CPEB2,TENM1,USPL1,SEC24B,PRKAG2,CAMKK2,GATM,PPARGC1A,HTATSF1,KCNB1,KCND2,LRP1B,KITLG,MITF,NOVA1,PIK3C2A,PPP3CA,FIGN,ATXN2,FNIP1,ANKRD12,CAMTA1,TCF4,FRYL" MicroRNA hsa-miR-3150b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-15 6.59E-12 2.43E-15 2.24E-14 39 230 "RNF157,ADD2,CASKIN1,PHF12,APBB2,CACNA1B,HAP1,METTL6,ARHGEF2,CRMP1,SLITRK5,SEC16A,EIF4G1,ING4,EIF1,MRVI1,AFF2,PDLIM5,CELF1,SRCAP,PRRC2B,ZBTB45,IDH3A,METTL21A,KCND1,MPP2,PFKFB3,BDNF-AS,SH3TC2,NCBP3,HES6,SLC8A1,TRIM67,UNC5B,PEG10,CAMTA2,ASTN2,TUBB2A,ZNF70" MicroRNA hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA_TOP PITA 1.25E-15 6.97E-12 2.57E-15 2.37E-14 33 165 "ADD1,MAP4K3,JAZF1,FOXN3,QKI,SNAP91,NR1D2,CPEB2,EIF4G2,MEX3B,ANKFY1,PSIP1,BACH2,MIER3,KTN1,MBNL1,MEF2C,PCDH9,KANSL1,OXR1,RET,ZFHX4,CPEB3,FAM81A,TET1,ERBIN,SYPL1,TCF4,SATB2,SLC44A1,PLEKHH2,ZNF24,HNRNPA3" MicroRNA hsa-let-7i*:mirSVR_lowEffct hsa-let-7i*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-15 7.01E-12 2.58E-15 2.38E-14 44 290 "INTS2,SUGT1P4-STRA6LP-CCDC180,ATP2A2,ARHGEF7,CBLN1,DCLK1,CCDC151,ARHGEF6,TCAF1,ARHGAP24,SPOCK2,SPOCK3,EGR3,EPB41L2,FGFR1,C2orf88,CELF1,FAM120B,LRRC37A6P,GLI2,ADAMTS6,TCEAL6,RBPJ,MEIS1,HNRNPM,ZC3H12B,NF1,GLIPR1L2,PCSK5,PDPK1,ING3,USP47,CCDC40,MEG3,PKNOX2,SEPHS1,MBD5,ATP10B,ZC4H2,HIF3A,TTC3,FAM155A,ZIC1,DPYSL5" MicroRNA hsa-let-7i*:mirSVR_highEffct hsa-let-7i*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-15 7.19E-12 2.65E-15 2.44E-14 32 155 "SEMA6A,ZFYVE28,CADPS,DST,CALB2,LRBA,AHCTF1,ZNF521,ERC2,CCDC144A,ADGRV1,ST6GALNAC3,ABLIM2,GRIA2,KCNN3,HECTD2,CNOT4,DPY19L2P2,SLC10A4,NALCN,EXOSC10,TMEM260,GTDC1,MRAP2,ST6GALNAC6,ADHFE1,DICER1,C9orf85,UGT8,CIAPIN1,WNK3,RTN4" MicroRNA hsa-miR-6504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-15 7.28E-12 2.68E-15 2.47E-14 50 367 "CLK4,TAOK1,SLC2A11,BACH1,LDHD,PLAA,LETMD1,CSNK1E,UBXN2A,USP6NL,ZC3H11A,SLC12A6,EIF4G2,MRNIP,TUBA1B,CEP78,GTF2IRD2,ZNF44,TRAF3IP2,TXNL4A,DIDO1,ZDHHC15,NKD1,ZIC5,IL6R,METTL21A,CYP27C1,SFXN5,MBD1,CHST6,MYCN,ZNF426,MINDY2,PPP2R5E,SETD5,C12orf49,HSPA4L,SLC12A2,TMCC1,FAM126B,SP2,TROVE2,DIP2A,ZMAT3,CBX5,PARD3,RPL7L1,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-4784:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-15 7.65E-12 2.82E-15 2.59E-14 39 231 "RNF157,ADD2,CASKIN1,PHF12,APBB2,CACNA1B,HAP1,METTL6,ARHGEF2,CRMP1,SLITRK5,SEC16A,EIF4G1,ING4,EIF1,MRVI1,AFF2,PDLIM5,CELF1,SRCAP,PRRC2B,ZBTB45,IDH3A,METTL21A,KCND1,MPP2,PFKFB3,BDNF-AS,SH3TC2,NCBP3,HES6,SLC8A1,TRIM67,UNC5B,PEG10,CAMTA2,ASTN2,TUBB2A,ZNF70" MicroRNA hsa-miR-4691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-15 7.65E-12 2.82E-15 2.59E-14 39 231 "ELFN2,ADD1,RNF150,PRX,BMPR1B,CA8,RTTN,C2CD2,LRIG1,PLCXD3,RCAN1,TMTC1,CELSR3,SLC43A2,TBC1D16,TMEM132C,FER,UFM1,GABRG2,FAM107A,C2CD4C,ITPKB,KIFC3,LSAMP,MAT2A,MID1,MYO5A,PKD1,PNMA3,KLHL11,HSD11B1L,NSFL1C,EXOC7,NSD1,TNS1,GORASP1,CRB2,SIGLEC10,FAM13C" MicroRNA hsa-miR-483-3p:Functional MTI Functional MTI miRTarbase 1.39E-15 7.79E-12 2.87E-15 2.64E-14 34 176 "ADCY6,KCTD16,PHF12,DPY19L3,CAMK2G,C2CD2,SUSD5,KIAA0408,DBN1,RCAN1,RASA4,DLC1,SLC37A3,SMC2,ZNF274,IGF1,TJAP1,KSR2,GPR137C,ZNF426,RASGRF1,GTDC1,BTBD3,ZHX3,UNC5B,EXOC7,USP22,PARD3,RUNDC3B,PLEKHH2,AGMO,CRB2,DPYSL5,DHX33" MicroRNA hsa-miR-718:mirSVR_lowEffct hsa-miR-718:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-15 7.95E-12 2.92E-15 2.69E-14 46 316 "CC2D2A,FAM131A,PPFIA3,ARNTL,LINC00173,MARK4,CHID1,USP6,CTH,OPTN,TBC1D16,GORAB,SLC9B2,NELFCD,TMEM107,APOPT1,TRAF3IP2,ZNF638,GPT2,STMN2,GRB10,AGBL5,LRRCC1,KIFC3,MEIS2,CDK18,TMIE,PLCB2,MAPKAP1,RET,ATAT1,LRFN5,SCP2,SLC12A4,SS18,SYP,TBCEL,SMG6,USP32P1,TPM1,C9orf85,UBTF,VLDLR,EML6,UPF3A,MSRB3" MicroRNA hsa-miR-362-5p:PITA hsa-miR-362-5p:PITA_TOP PITA 1.47E-15 8.24E-12 3.03E-15 2.79E-14 30 136 "SYS1,ZBTB10,NRXN3,RBM39,RIMS4,CASP8AP2,APH1A,TMEM132E,ERBB4,MRVI1,CORO2B,RAPGEF6,C15orf41,MIER3,STRN3,PRKACB,PTPRD,PTPRE,CEP97,REV3L,SLC25A36,RMI1,SATB1,CASC3,ST6GAL1,CPEB4,NUDT10,SYN1,SATB2,TRPS1" MicroRNA hsa-miR-3689d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-15 8.28E-12 3.04E-15 2.80E-14 49 355 "ABCF1,HACE1,DOCK11,DDR1,PTBP2,CBS,PITPNM3,GAPVD1,DNAL1,DUSP9,APH1A,MRO,COQ7,FGFR1,LILRA2,SHISA6,IGF1,SLC6A17,MXI1,TBC1D25,PKM,SMOX,PPARA,CNNM2,NCR3LG1,MTMR10,CEP97,RAP1GDS1,PGBD4,NCBP3,AMBRA1,SLC2A5,EPN2,KIF13A,SOX11,UNC5B,CDK19,DDN,AGTPBP1,SLC19A3,WBP2,SSBP2,BCL2L13,LAT2,ZNF17,SMARCAD1,EVI5,CIAPIN1,PARP11" MicroRNA hsa-miR-384:PITA hsa-miR-384:PITA_TOP PITA 1.56E-15 8.74E-12 3.21E-15 2.96E-14 32 156 "PCDH19,TAOK1,PPP4R4,CAMK2G,FOXN3,SLC35F1,ABCG1,RIMS4,MFAP3L,POM121,MBNL2,TENM1,RCAN2,UBE2E3,GFRA2,GGT7,MPP2,PDE4D,GPR85,STRN3,PTN,ZNF532,CLIP1,FBXO11,SLC8A1,KBTBD4,NKAIN2,ERBIN,TCF4,R3HDM1,TSC1,ZNF189" MicroRNA hsa-miR-6792-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-15 8.88E-12 3.26E-15 3.00E-14 39 232 "ELFN2,ADD1,RNF150,PRX,BMPR1B,CA8,RTTN,C2CD2,LRIG1,PLCXD3,RCAN1,TMTC1,CELSR3,SLC43A2,TBC1D16,TMEM132C,FER,UFM1,GABRG2,FAM107A,C2CD4C,ITPKB,KIFC3,LSAMP,MAT2A,MID1,MYO5A,PKD1,PNMA3,KLHL11,HSD11B1L,NSFL1C,EXOC7,NSD1,TNS1,GORASP1,CRB2,SIGLEC10,FAM13C" MicroRNA hsa-miR-4643:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-15 9.31E-12 3.42E-15 3.15E-14 34 177 "KCTD16,TAOK1,TNRC6C,CADPS,STX16,BACH1,LONRF2,BAG4,CRY2,SPOCK2,CPEB2,CERCAM,TUBA1B,MTHFD2,COPS8,GLI2,PADI2,HLF,KLHL23,SYTL4,ZNF827,PIK3R1,PURG,PNMA8A,STX1B,STUM,ZNF415,NSFL1C,SYT5,SIK3,NR2C2,UBE2H,RTN4,SPATA13" MicroRNA hsa-miR-205:PITA hsa-miR-205:PITA_TOP PITA 1.69E-15 9.43E-12 3.46E-15 3.19E-14 43 280 "PTCHD1,HACE1,PI16,NCOA1,SLC4A4,CFL2,CHN1,B4GALT6,CLTC,QKI,ELMSAN1,CPEB2,PHC2,CNNM1,CALCRL,EPB41,ERBB4,ACSL4,ST6GALNAC3,CHIC1,KITLG,TBC1D25,CLDN11,TMEM260,LRRK2,HUNK,CLIP1,CPEB3,BTBD3,TET1,CXXC4,KDM4B,SP4,CDK19,SS18,PLCB1,MGRN1,SATB2,CUX2,TP53BP2,TRPS1,FAM155A,ADAMTS9" MicroRNA hsa-miR-299-3p:PITA hsa-miR-299-3p:PITA_TOP PITA 1.73E-15 9.70E-12 3.56E-15 3.28E-14 27 109 "RTL9,OSBPL8,SEMA6A,MADD,ZBTB10,RUNX1T1,SLC35F1,CLIP3,DOCK4,IP6K1,APH1A,TMEM35A,GRIN2D,KAT7,IGF1,GIT1,MSI1,GNG2,SGSM1,CSRNP3,CHD9,FAM126B,SP4,MTCL1,TCF4,UBE2H,RNF146" MicroRNA hsa-miR-6512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-15 9.78E-12 3.59E-15 3.30E-14 61 523 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,ARSE,GPR146,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,MTX3,EBI3,IRAK4,ANKFY1,TRMO,ZNF234,CRCP,GPR75,GPT2,PARD3B,DDX19B,AGBL5,SLC6A17,CHST6,ZC3H12B,SLC11A2,MTRF1L,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ZNF331,SALL1,SGK1,SEPHS1,RADIL,FAM126B,MCF2L2,SSTR2,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-642:PITA hsa-miR-642:PITA_TOP PITA 1.81E-15 1.01E-11 3.71E-15 3.41E-14 33 167 "PCDH19,CDH2,CLCN3,LRIG1,EBF1,EMX2,EPHB1,ERBB4,FGF1,MEGF11,PCDH17,PPARGC1A,GPD2,NEGR1,AGFG1,KIF5A,LSS,PIK3R1,EPB41L4B,PPP3CA,TMEM260,ZFHX4,FAM214B,FAM126B,KDM4C,SS18,ERBIN,SEPT3,AP4E1,LRRC8A,TNS1,ZFAND5,WNK3" MicroRNA hsa-miR-652:mirSVR_lowEffct hsa-miR-652:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-15 1.01E-11 3.71E-15 3.42E-14 46 318 "BEND6,SUGT1P4-STRA6LP-CCDC180,PKP4,ADGRB2,NRP2,SLC16A4,LRBA,ARHGEF6,CDC42BPB,NCOR2,ARHGEF10,SACS,TOM1,ELN,DCTN4,PIPOX,DLC1,GABRB3,GALC,RAB40B,MAN2A2,MATN2,MATN3,TM6SF1,MPP2,VWA2,LOC100128398,PDPK1,FAM66C,ZNF793,OXR1,SCN8A,FERMT1,FAM81A,SLC11A1,MTERF2,ZFP1,RCOR3,MYO16,KDM4C,TCF12,TTTY15,VLDLR,ZFAND5,MAP3K12,JPH3" MicroRNA hsa-miR-4282:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-15 1.03E-11 3.77E-15 3.47E-14 44 293 "RALGAPA1,XKR4,SPOP,SFMBT2,ZNF582,CCPG1,CLCN3,QKI,HDAC4,DBN1,ELMSAN1,CPEB2,EDN3,MRNIP,C8orf37,DCTN4,ENPP6,SRRM1,COPS8,FAM107A,CHIC1,NFYA,NRCAM,GPR137C,PDE4D,PDZRN4,KANSL1,PTPRG,REV3L,GTDC1,KLHL11,RORB,TRA2B,EPN2,SLC8A1,EPC1,SP4,TROVE2,NECAB1,DICER1,ZMAT3,ZXDA,PRDM10,KCNAB1" MicroRNA "ATGTTTC,MIR-494:MSigDB" "ATGTTTC,MIR-494:MSigDB" MSigDB 1.90E-15 1.07E-11 3.90E-15 3.59E-14 31 147 "OSBPL6,OGT,ARNTL,DBN1,DMD,EGR3,EIF5,NBEA,PPARGC1A,ADAMTS6,HAS2,ELOVL5,LRP1B,ZC3H12B,NOVA1,PCSK1,PRTG,ING3,ANKHD1,TMEM255A,CHD9,FBXO11,MBD5,SP4,STAC2,SYNE2,TACC1,SZT2,TRPS1,ZIC2,ADAMTSL3" MicroRNA hsa-miR-548ah-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-15 1.14E-11 4.18E-15 3.85E-14 46 319 "FMNL2,FZD9,SEMA7A,SRSF11,EPS15L1,RTTN,CPS1,APPL1,UBXN2A,DCAF8,FBXL5,RAB39B,HIPK3,FEM1B,FCF1,KMT5B,CERCAM,MSANTD4,C15orf41,SESN1,CRCP,CBX1,LUZP2,FUT10,GRB10,RBPJ,KCNB1,STMN1,PFKFB3,ZFYVE21,LRP12,SH3KBP1,PRKCB,PEX2,CEP97,TMEM200C,FAM126B,SP4,TAF6,SATB2,NACC2,RGMB,EMSY,ADAMTS9,ITM2C,WNK3" MicroRNA hsa-miR-502-5p:PITA hsa-miR-502-5p:PITA_TOP PITA 2.05E-15 1.14E-11 4.19E-15 3.86E-14 29 128 "OGT,CARMIL3,LDLRAD4,RBM39,NCOR2,RIMS4,DAPK1,EIF4G2,PAN3,AKAP3,DOT1L,RAB30,BACH2,MIER3,KITLG,HS6ST3,MXI1,CNOT4,ZNF827,PTCH1,PTPRE,FIGN,CASC3,NUDT10,ANKRD12,TCF4,SIRT1,RIMBP2,HNRNPA3" MicroRNA "ACTGAAA,MIR-30A-3P:MSigDB" "ACTGAAA,MIR-30A-3P:MSigDB" MSigDB 2.09E-15 1.17E-11 4.27E-15 3.93E-14 35 189 "OSBPL6,APC,ATP1A1,RUNX1T1,USP6,QKI,CSNK1E,CSNK1G3,IPCEF1,EIF1,ERBB4,DNAJC27,MED12L,DBF4,PSIP1,NEGR1,LRRTM1,MARK1,MEF2C,NRCAM,PPP2R5E,RAD51D,PBRM1,ROBO1,FBXW7,RYR3,SH3GL3,NKAIN2,AP4E1,NR2C2,HIRA,USP1,RICTOR,USP32P2,FXR1" MicroRNA "ACTGAAA,MIR-30E-3P:MSigDB" "ACTGAAA,MIR-30E-3P:MSigDB" MSigDB 2.09E-15 1.17E-11 4.27E-15 3.93E-14 35 189 "OSBPL6,APC,ATP1A1,RUNX1T1,USP6,QKI,CSNK1E,CSNK1G3,IPCEF1,EIF1,ERBB4,DNAJC27,MED12L,DBF4,PSIP1,NEGR1,LRRTM1,MARK1,MEF2C,NRCAM,PPP2R5E,RAD51D,PBRM1,ROBO1,FBXW7,RYR3,SH3GL3,NKAIN2,AP4E1,NR2C2,HIRA,USP1,RICTOR,USP32P2,FXR1" MicroRNA "GTGTTGA,MIR-505:MSigDB" "GTGTTGA,MIR-505:MSigDB" MSigDB 2.09E-15 1.17E-11 4.28E-15 3.94E-14 26 101 "ARNTL,ATP2B2,USP6,FAM19A5,GDA,KIAA0408,CELF1,CYP46A1,CAMK2N2,MBNL1,MXI1,MYCN,PCDH9,PDE4D,PDPK1,GPR85,PMP22,STRN3,USP47,FIGN,EPN2,SLC12A2,ARHGAP26,TTBK2,ZIC2,USP32P2" MicroRNA hsa-miR-371a-5p:Functional MTI Functional MTI miRTarbase 2.10E-15 1.17E-11 4.29E-15 3.95E-14 48 345 "TMEM132B,SLC24A4,TXNDC16,CPNE5,ZBED1,ZNF445,STOML1,ARHGEF6,SEC14L5,PYGO1,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,FEM1B,PLEKHA1,C8orf37,COQ7,SRCAP,TNRC6A,FUT10,HAS2,DDX19B,ZNF678,CHST6,MITF,DBNL,MYCN,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,SP4,ADAMTS17,SLC19A3,VWCE,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,ZNF24" MicroRNA hsa-miR-374b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-15 1.19E-11 4.35E-15 4.01E-14 39 234 "ABCF1,XKR4,ADD2,STX16,NRP2,CA8,SOCS6,NRXN3,ABCG2,PITPNC1,TMTC1,MBNL2,ACSL4,DLC1,POLR1B,SEC23B,ANKFY1,ZBED3,GABRG2,TNRC6A,LUZP2,BACH2,MIER3,L1CAM,SLC11A2,OCRL,EPDR1,MAPK7,BTBD3,STAU1,SYP,TACC1,TRIM2,SIK3,NR2C2,TRPS1,UBE3A,ZFP37,SLC38A1" MicroRNA hsa-miR-6790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-15 1.22E-11 4.47E-15 4.11E-14 43 282 "AS3MT,TAOK1,PHF12,VXN,STOML1,ENTPD4,MYADM,DBT,CHRDL1,SEC24B,SRCAP,HAS2,DDX19B,C2orf72,IL6R,KCNN1,KCNN3,MAN2A2,MBNL1,CHST6,AFF1,P2RX7,TMOD2,PIK3C2A,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,HSPA4L,NUBPL,ZNF430,ANKRD36,FAM126B,ZBTB43,SSTR2,STAC2,KLHL7,ZNF34,USP1,ZNF708,GAN" MicroRNA hsa-miR-599:PITA hsa-miR-599:PITA_TOP PITA 2.24E-15 1.26E-11 4.58E-15 4.22E-14 30 138 "OGT,SLC4A4,STX16,USP6,CNTFR,TAOK3,AGAP2,FOXO3,BRSK1,C15orf41,KDM2B,IGF1,RBPJ,MXI1,PDE3A,PDE4B,PDE4D,PTPRD,SOX11,SP4,CLASP2,SEPT3,ARHGEF9,SATB2,TCF12,TRPS1,FLRT2,KAT6A,HNRNPA3,JMJD1C" MicroRNA hsa-miR-125a-5p:Functional MTI Functional MTI miRTarbase 2.25E-15 1.26E-11 4.59E-15 4.23E-14 42 270 "MTUS1,OGT,ZBTB10,PRC1,LONRF2,ZNF385A,PREPL,HDAC4,IP6K1,GUCD1,NR1D2,EDN1,EGFR,ERBB2,SMC2,MUM1,NEGR1,JAK2,SLC35G1,LIFR,MAT2A,NTRK3,OPRL1,PDPK1,PPP2R5E,MASP1,UBR7,EMID1,MEG3,COPZ1,FERMT1,PEG10,DIP2A,PCDHGB2,PUM2,TRPS1,XPO1,ZNF177,DHX33,STOX2,WNK3,TMEM63C" MicroRNA hsa-miR-3609:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-15 1.29E-11 4.70E-15 4.32E-14 46 320 "FMNL2,FZD9,SEMA7A,SRSF11,EPS15L1,RTTN,CPS1,APPL1,UBXN2A,DCAF8,FBXL5,RAB39B,HIPK3,FEM1B,FCF1,KMT5B,CERCAM,MSANTD4,C15orf41,SESN1,CRCP,CBX1,LUZP2,FUT10,GRB10,RBPJ,KCNB1,STMN1,PFKFB3,ZFYVE21,LRP12,SH3KBP1,PRKCB,PEX2,CEP97,TMEM200C,FAM126B,SP4,TAF6,SATB2,NACC2,RGMB,EMSY,ADAMTS9,ITM2C,WNK3" MicroRNA hsa-miR-378a-5p:Functional MTI Functional MTI miRTarbase 2.40E-15 1.35E-11 4.90E-15 4.52E-14 51 386 "TMEM132B,TAOK1,TNRC6C,STOML1,ENTPD4,MYADM,TCAF1,DBT,AP4B1,SIGLEC8,SRCAP,PPARGC1A,HAS2,DDX19B,C2orf72,KCNN1,KCNN3,MAN2A2,CHST6,PTOV1,P2RX7,TMOD2,PIK3C2A,GPSM2,ING3,POLR2F,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,HSPA4L,NUBPL,ZNF430,ANKRD36,CMTR2,FAM126B,ZBTB43,SSTR2,STAC2,KLHL7,ARC,CYB561A3,ZMAT3,ZNF34,SGK3,UGT8,USP1,ZNF708,GAN" MicroRNA hsa-miR-520b:Functional MTI Functional MTI miRTarbase 2.43E-15 1.36E-11 4.96E-15 4.57E-14 56 455 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,EGFR,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-2467-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.44E-15 1.36E-11 4.97E-15 4.57E-14 55 441 "ABCF1,NDRG3,HECW2,TRMT9B,IGDCC4,ATP1B3,SYNJ2,CCNT1,CBFA2T2,NUMBL,EPS15L1,NRXN3,ABCC5,APH1A,RASA4,MRNIP,MTSS1L,ANKMY1,KATNAL1,AMOTL2,MTHFD2,SRCAP,SESN1,AHDC1,CRCP,COPS8,TNRC6A,GNG4,TPPP,KAT7,ATOH8,PADI2,DDX19B,ZNF546,RBPJ,IBA57,ZNF678,IPO5,NLE1,RETREG2,TMEM104,SH3TC2,GSTCD,KIAA0895L,FAM102A,PEX26,ATF7IP,SLC37A2,IQCE,NACC2,BHLHB9,WBP2,ZNF70,CIAPIN1,GAN" MicroRNA hsa-miR-627-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-15 1.40E-11 5.10E-15 4.70E-14 45 308 "RALGAPA1,RNF150,SPOP,ABCD2,RASL11B,DLGAP2,VCAN,PLCXD3,ZSCAN23,YTHDC1,TMTC1,EIF1,EPHB1,REEP2,HHIPL1,GABRG2,GCK,CRCP,PRRC2B,HAS2,SLC6A17,SLC35G1,MID1,NCAM2,NOVA2,P2RX7,OLA1,EPB41L4B,PRKCB,ZSCAN2,FNIP1,SH3BP2,CHD9,RBM26,EXOC7,TNS1,TUBB2A,ZNF610,UBE2H,DHX33,SLC30A4,CADM2,FAM13C,PHTF2,JMJD1C" MicroRNA hsa-miR-517c:mirSVR_highEffct hsa-miR-517c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.60E-15 1.45E-11 5.29E-15 4.87E-14 41 259 "FMNL2,ELFN2,KCTD16,ADGRF5,ALCAM,LURAP1,DGKI,B4GALT6,QKI,ABI3BP,ZNF521,GAPVD1,KIF26A,LONRF1,DBN1,NR1D2,RASGRP1,EGFR,PRMT5,POLR1B,ARFIP1,AHDC1,GGT7,GHR,HPGDS,GRIA2,MSL1,ITPKB,JAK2,STMN1,NUDT11,MBD5,TMCC1,CEP68,TMEM150C,AP4E1,SLC44A1,TNS1,USP1,EML6,CASC15" MicroRNA hsa-miR-628-5p:PITA hsa-miR-628-5p:PITA_TOP PITA 2.77E-15 1.55E-11 5.64E-15 5.19E-14 32 159 "RTL9,CASK,BLM,PTBP2,CAMK2G,QKI,RIMS2,GOLT1B,NBEA,OGA,GPD1,HMGCR,KTN1,MAT2A,MEF2C,MEIS1,MEIS2,MYO5A,MYO6,PRTG,PDPK1,NALCN,PPP5C,RCOR3,SP2,NKAIN2,TCF4,TRIM2,AP4E1,SMARCAD1,TMEM178A,HNRNPA3" MicroRNA hsa-miR-6721-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-15 1.60E-11 5.80E-15 5.34E-14 39 236 "ELFN2,CASKIN1,AMH,PHF12,DPY19L3,HCN2,CAMK2A,NUMBL,CACNA2D2,MYADM,TM9SF4,IP6K1,DNAL1,FAM13A,CELF1,CPLX1,AHDC1,GFER,CRCP,MAP4,PPM1L,HS6ST3,ZC3H12B,PDE4A,PIK3R1,PKD1,POLR2F,SARS,STUM,PEX26,TMCC1,SSTR1,PUM2,NACC2,CBX5,RGMB,TMEM237,ITM2C,GAN" MicroRNA hsa-miR-886-5p:mirSVR_lowEffct hsa-miR-886-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.89E-15 1.62E-11 5.88E-15 5.42E-14 49 361 "ASPHD1,ARNTL,LINC00173,ADAM15,ADGRB1,CA12,CALM1,LETMD1,RASGEF1C,MYADM,POM121,SGSM2,DMPK,DPH1,EGR3,C3orf18,RASL12,RACK1,FCGRT,SMC2,TPK1,SIGLEC8,USP19,TCERG1,GLI2,GNAO1,MAN1B1,GPR62,MYT1,FXYD7,LOC100128398,SLC26A11,CNNM2,BCAS3,GDPD2,RGS12,KCTD17,CPEB3,SLC2A5,CLSTN2,ZC4H2,PCDHB9,HIF3A,DICER1-AS1,METTL3,TSN,TSC1,LAT2,CASC15" MicroRNA hsa-miR-548n:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-15 1.67E-11 6.05E-15 5.57E-14 41 260 "PTCHD1,MTUS1,MARCH4,FAM135A,PTBP2,TOGARAM2,NECTIN3,PYGO1,YTHDC1,RAB39B,DPYSL2,KATNAL1,SUCO,ZMAT1,MTHFD2,CRCP,TNRC6A,PRRC2B,MAP4K5,SOWAHA,ZNF678,TTYH2,TM6SF1,PFKFB2,ZFYVE21,PSAT1,SLC25A36,C12orf49,MCMBP,CLIP1,TRA2B,PEG10,TRPS1,RPL7L1,MTCH1,VSNL1,ZNF154,DHX33,PPP1R3F,WNK3,JMJD1C" MicroRNA hsa-miR-6770-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.11E-15 1.74E-11 6.31E-15 5.81E-14 38 225 "TRMT9B,SEMA7A,CDC14B,IGDCC4,ZNF445,LETMD1,AKAP5,RNF14,SLITRK5,KIAA0040,ZC3H11A,CHRDL1,EGR3,ING4,MTSS1L,SLC43A2,MRVI1,FAM49B,TRAF3IP2,CRCP,LRRC75A,IDH3A,MAP2,SCAMP5,SAMD14,NWD1,ARMH4,LIMS2,STX1A,ASTN2,FBXW11,ZNF34,ARL10,TPM2,TUBB2A,SIGLEC10,URM1,ITM2C" MicroRNA hsa-miR-142-5p:Functional MTI Functional MTI miRTarbase 3.11E-15 1.74E-11 6.31E-15 5.81E-14 38 225 "CC2D2A,SEMA7A,CALM1,RIMS4,UBXN2A,FAM107B,CERCAM,RCAN2,DLC1,FOXO3,C15orf41,LUZP2,FUT10,BACH2,MAT2A,MKLN1,NFE2L2,PDE4D,ZFYVE21,PDZRN4,PRKCB,PEX2,CEP97,FIGN,ALG9,ROBO1,FAM126B,ZBTB43,ANKRD28,ZEB1,SIRT1,TNS1,RGMB,SMUG1,UBE2H,ZNF711,SLC38A1,STOX2" MicroRNA "AGGAGTG,MIR-483:MSigDB" "AGGAGTG,MIR-483:MSigDB" MSigDB 3.29E-15 1.84E-11 6.69E-15 6.16E-14 21 63 "OGT,CAMK2G,USP6,QKI,PHACTR3,PHF20L1,RCAN2,FHL1,IGF1,CAMK2N2,MAP2,NTRK3,SATB1,CPEB3,AMBRA1,PKNOX2,SLC6A8,R3HDM1,SYNPO2,XPO1,USP32P2" MicroRNA hsa-miR-1237:PITA hsa-miR-1237:PITA_TOP PITA 3.31E-15 1.85E-11 6.71E-15 6.18E-14 37 214 "ESYT2,AMPH,SLC4A4,EIF4G3,GPC2,SLC25A14,NRXN3,AHCTF1,ZNF385A,SPATA2,MED12L,UBE2E3,TCERG1,SPIN1,PCLO,GRB10,PTPRT,HLF,KIFC3,MAT2A,PTPRD,FIGN,RFX2,ZFHX4,RYR3,CPEB4,ZNF423,NKAIN2,PHLDB1,ANKRD28,TNS1,ZIC2,WNK3,KAT6A,HNRNPA3,FXR1,JPH3" MicroRNA hsa-miR-590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-15 2.05E-11 7.44E-15 6.85E-14 51 390 "APC,STX16,BACH1,PTBP2,LETMD1,BAG4,UBXN2A,USP6NL,YTHDC1,MYEF2,FARSB,SEMA3D,KMT5B,RASA4,PLEKHA1,C8orf37,RAB9B,AMOTL2,SEC23B,PCYOX1,FAM49B,MSANTD4,MALT1,ZNF276,RNPS1,CBX1,GRIK4,MIER3,IL6ST,ITPKB,LIMS1,MBNL1,CHIC1,TM6SF1,MXI1,SH3KBP1,SETD5,RPL15,FBXW7,FAM161B,TRA2B,SLC8A1,AGTPBP1,KIAA0930,ZEB1,KAT6B,TRPS1,SSBP2,ZFP37,PHTF2,JMJD1C" MicroRNA hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA_TOP PITA 3.85E-15 2.16E-11 7.82E-15 7.20E-14 37 215 "BCL7A,PTBP2,KRIT1,SOCS6,B4GALT6,CLTB,IGDCC3,RBM39,CRMP1,CRY2,CSNK1G3,ERC2,DAPK1,IP6K1,ALKBH8,CHRDL1,EIF4G1,ERBB4,ADAM28,RNF165,MAP2,MGAT3,MYT1,PDE4D,OLA1,ZFHX4,RPE,BTBD3,CPEB4,FAM219A,SYT1,CAMTA1,TAL1,RIMBP2,CLDND1,TMEM237,NAV3" MicroRNA hsa-miR-329:PITA hsa-miR-329:PITA_TOP PITA 3.85E-15 2.16E-11 7.82E-15 7.20E-14 37 215 "BCL7A,PTBP2,KRIT1,SOCS6,B4GALT6,CLTB,IGDCC3,RBM39,CRMP1,CRY2,CSNK1G3,ERC2,DAPK1,IP6K1,ALKBH8,CHRDL1,EIF4G1,ERBB4,ADAM28,RNF165,MAP2,MGAT3,MYT1,PDE4D,OLA1,ZFHX4,RPE,BTBD3,CPEB4,FAM219A,SYT1,CAMTA1,TAL1,RIMBP2,CLDND1,TMEM237,NAV3" MicroRNA hsa-miR-410-3p:Functional MTI Functional MTI miRTarbase 3.90E-15 2.18E-11 7.91E-15 7.28E-14 40 250 "ABCF1,ADD2,ZNF608,CA8,NSL1,USP6NL,DGKG,CPEB2,MBNL2,CERCAM,RGS17,ACSL4,POLR1B,ZBED3,TCERG1,COPS8,TPPP,BACH2,SCIN,ITPKB,KLHL23,NTRK3,OCRL,XRN1,PPP2R5E,ZFP30,SLC8A1,ZHX3,PRRC2C,SYP,TRIM2,SIK3,HEY1,DOK6,RGMB,OSBP2,MAP3K12,ZXDA,CADM2,STOX2" MicroRNA hsa-miR-3179:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-15 2.22E-11 8.05E-15 7.41E-14 34 182 "TRMT9B,OGT,APAF1,HCN2,CA8,ZNF385A,IP6K1,SPATA2,DUSP9,MRO,POLL,ZNF496,NXPH3,TNFAIP8L3,ZFYVE27,MAT2A,SAMD14,CLDN11,PKM,KCTD15,FXYD1,EPB41L4B,SH3TC2,SETD5,SH3BP2,SP2,USP22,ZNF34,NACC2,UBTF,INTS3,CIAPIN1,URM1,GAN" MicroRNA hsa-miR-4500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-15 2.28E-11 8.24E-15 7.58E-14 45 312 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,TRMO,PDLIM5,CELF1,DISC1,GATM,POLL,FUT10,RABL2A,IL6R,KPNA5,THYN1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1" MicroRNA hsa-miR-4458:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-15 2.28E-11 8.24E-15 7.58E-14 45 312 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,TRMO,PDLIM5,CELF1,DISC1,GATM,POLL,FUT10,RABL2A,IL6R,KPNA5,THYN1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1" MicroRNA "CTCTGGA,MIR-520A:MSigDB" "CTCTGGA,MIR-520A:MSigDB" MSigDB 4.16E-15 2.33E-11 8.43E-15 7.76E-14 30 141 "FZD9,PCDH19,OGT,BCL7A,CAMK2A,CAMK2G,CAPN3,SEPT7,STOML1,CLTB,QKI,NCOR2,TMCC2,GFRA2,CDH20,MEIS2,NOVA1,SLC11A2,ZNF655,MAPKAP1,PPP2R5E,SEMA6D,ARHGEF40,FNBP1,POGZ,SATB2,NSD1,PUM2,WNT7A,PPP1R3F" MicroRNA "CTCTGGA,MIR-525:MSigDB" "CTCTGGA,MIR-525:MSigDB" MSigDB 4.16E-15 2.33E-11 8.43E-15 7.76E-14 30 141 "FZD9,PCDH19,OGT,BCL7A,CAMK2A,CAMK2G,CAPN3,SEPT7,STOML1,CLTB,QKI,NCOR2,TMCC2,GFRA2,CDH20,MEIS2,NOVA1,SLC11A2,ZNF655,MAPKAP1,PPP2R5E,SEMA6D,ARHGEF40,FNBP1,POGZ,SATB2,NSD1,PUM2,WNT7A,PPP1R3F" MicroRNA hsa-miR-518f:mirSVR_highEffct hsa-miR-518f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.39E-15 2.45E-11 8.87E-15 8.17E-14 39 239 "AXIN2,LRFN2,ZNF608,PCDH19,CASK,CFAP410,AKAP6,SMARCAL1,SOCS5,DTNA,GMPR2,ACSL4,GORAB,FHL1,SYT17,KDM2B,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,ZC3H12B,ZNF827,APTX,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,TBCEL,NSD1,KAT6B,TSN,PLEKHH2,KCNK12,EMSY,PRTFDC1,PARP11" MicroRNA hsa-miR-107:Functional MTI Functional MTI miRTarbase 4.41E-15 2.47E-11 8.92E-15 8.21E-14 44 300 "ADD2,AXIN2,SEMA6A,OGT,ZBTB10,NUMB,DOCK11,DST,MTMR3,RUNX1T1,CCNT1,TBPL1,CLOCK,CSNK1G3,VCAN,PPP1R16B,TMEM170A,DAPK1,YTHDC1,GUCD1,DMPK,FCF1,YAF2,PLEKHA1,ZNF585B,TUBA1B,ANKFY1,IDH3A,ZNF680,NF1,PCSK5,ENPP2,PIK3R1,CNNM2,RBBP6,ZDHHC4,FBXW7,CLIP1,SALL1,CPEB3,DICER1,NACC2,ZBTB38,DHX33" MicroRNA hsa-miR-1178:PITA hsa-miR-1178:PITA_TOP PITA 4.46E-15 2.49E-11 9.01E-15 8.30E-14 33 172 "RTL9,SPAG9,ZNF385A,CLOCK,CRY2,DOCK4,C2CD2L,GRIN3A,NR1D2,CPEB2,EGR3,EIF5,NCALD,NRN1,PSD2,STAU2,TMEM121B,PCLO,MIER3,MARK1,MAT2A,GPR85,MAPK9,ZMAT4,RIC8B,SNCA,HECW1,TNS2,RIMBP2,EVI5,NAV3,HNRNPA3,MSRB3" MicroRNA hsa-miR-646:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-15 2.51E-11 9.05E-15 8.33E-14 40 251 "TAOK1,TRMT9B,CASK,MTMR3,CA8,CCNT1,TMEM184B,BAG4,CSNK1E,SOCS5,KIAA0408,YTHDC1,POM121,DMTF1,FEM1B,PLEKHA1,DLC1,PCYOX1,ELOVL5,IRF8,MYO5A,OCRL,PIK3R1,PSAT1,CNNM2,PTPRD,ZFHX4,SETD5,SALL1,ZFP30,FNDC3A,MPRIP,KANK1,GPRIN3,ZMAT3,ZNF106,DHX33,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-1185:PITA hsa-miR-1185:PITA_TOP PITA 4.51E-15 2.52E-11 9.11E-15 8.39E-14 26 104 "USP37,CA8,KRIT1,CRY2,HINFP,MFAP3L,TMCC2,DPH1,YAF2,FGF14,GABRB3,ADAMTS6,BACH2,IL6ST,MAT2A,RETREG2,OXR1,SLC12A2,PEG10,CLASP2,NKAIN2,SEPT8,PRRC2C,TCF12,TRPS1,WNK3" MicroRNA hsa-miR-181d-5p:Functional MTI Functional MTI miRTarbase 4.71E-15 2.64E-11 9.51E-15 8.76E-14 43 288 "MTUS1,HECW2,HFM1,MARCH4,ARRB2,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,MTX3,FSD1L,FAM13A,STX2,IQCG,MALT1,DHRS4,ZDHHC15,IPO5,NCOA7,BLOC1S2,PPP2R5E,ZNF844,PBRM1,MEG3,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,CPEB4,ZNF667,ZNF415,TMCC1,UNC5B,PRRC2C,MGRN1,SLC35G2,TUBB2A,ZNF781,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-210:mirSVR_highEffct hsa-miR-210:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.79E-15 2.68E-11 9.66E-15 8.90E-14 35 194 "CC2D2A,ADGRB3,ST3GAL5,RUNX1T1,CHN1,CNRIP1,IP6K1,GIT2,DLX1,NR1D2,ABCA8,TAOK3,CORO2B,C2orf88,AIFM3,DIDO1,PRDM5,ARHGAP36,SLC35G1,IPO5,STMN1,MARK1,NEFM,SEMA5B,FAM218A,TTC13,RNASEL,CARF,ZFP2,ATF7IP,SMARCA4,USP32P1,DCBLD1,CIAPIN1,MPPE1" MicroRNA hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.79E-15 2.68E-11 9.66E-15 8.90E-14 55 448 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-6852-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.84E-15 2.71E-11 9.76E-15 8.99E-14 38 228 "AS3MT,ARHGDIA,SLC4A4,CBS,DIS3L,CSNK1E,PLXNA4,ZBTB24,KLHL3,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,KDM2B,LILRA2,CHST6,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,BDP1,FNBP1,ALG1,AGTPBP1,CLASP1,ARL10,CBX5,PARD3,SSBP2,KLC2,RNF170" MicroRNA hsa-miR-208b-3p:TargetScan hsa-miR-208b-3p TargetScan 4.85E-15 2.71E-11 9.77E-15 8.99E-14 32 162 "KCTD16,OSBPL1A,LRCH2,APC,MTMR3,PTBP2,CDH2,CFL2,QKI,HDAC4,SCRN1,MTX3,EBF1,EIF4G2,EIF5,GLYR1,LRRTM1,KCNN3,MEIS1,MMP16,NOVA1,PTPRG,SATB1,SCN2B,FNIP1,CHD9,FNDC3A,CNKSR2,POGZ,LRRC8A,REEP1,ANKS1B" MicroRNA hsa-miR-208a-3p:TargetScan hsa-miR-208a-3p TargetScan 4.85E-15 2.71E-11 9.77E-15 8.99E-14 32 162 "KCTD16,OSBPL1A,LRCH2,APC,MTMR3,PTBP2,CDH2,CFL2,QKI,HDAC4,SCRN1,MTX3,EBF1,EIF4G2,EIF5,GLYR1,LRRTM1,KCNN3,MEIS1,MMP16,NOVA1,PTPRG,SATB1,SCN2B,FNIP1,CHD9,FNDC3A,CNKSR2,POGZ,LRRC8A,REEP1,ANKS1B" MicroRNA hsa-miR-496.2:TargetScan hsa-miR-496.2 TargetScan 4.86E-15 2.72E-11 9.78E-15 9.01E-14 29 132 "DPP10,ATP2B2,BACH1,CNTNAP2,PYGO1,ELMSAN1,DNAJB6,EPB41L2,SEC23B,MSANTD4,FAM19A2,PAXBP1,LRP1B,PCSK1,PDE4D,PFKFB3,GPSM2,RAD51D,RGS4,AP1AR,CSRNP3,SEC14L1,HSPA4L,DHX30,LMO3,LARP4,ITGB3BP,NACC2,CBX5" MicroRNA hsa-miR-1245:PITA hsa-miR-1245:PITA_TOP PITA 4.86E-15 2.72E-11 9.78E-15 9.01E-14 29 132 "LCORL,CLTC,OSBPL3,DUSP9,PHF20L1,RCAN2,FECH,SUCO,AFF2,PCDH17,GRB10,LINGO1,NEXMIF,ZC3H12B,NPTX1,OCRL,TMEM260,TMEM255A,USP47,RDX,ATXN2,NLGN1,RCOR3,TMCC1,SP4,R3HDM1,EMSY,WNK3,SOCS4" MicroRNA "ACCATTT,MIR-522:MSigDB" "ACCATTT,MIR-522:MSigDB" MSigDB 5.08E-15 2.84E-11 1.02E-14 9.41E-14 31 152 "CASKIN1,LRCH2,CAPN3,EVI5L,CNTFR,ARMCX2,MYEF2,ZC3H11A,APH1A,ETV1,SUCO,SYNCRIP,CSPG5,KDM2B,GNAO1,MBNL1,LRP1B,HNRNPM,ZC3H12B,NFE2L2,ING3,ZNF532,SALL1,PPM1E,SP4,NMNAT2,MYCBP2,LMO3,RPGRIP1L,UBE3A,WNK3" MicroRNA hsa-miR-1267:PITA hsa-miR-1267:PITA_TOP PITA 5.08E-15 2.84E-11 1.02E-14 9.41E-14 31 152 "HECW2,PCDH19,APC,SHROOM2,PPP4R4,ATP1B3,JAZF1,RUNX1T1,C1orf52,CSNK1G3,SOCS5,USP6NL,CHRDL1,AGAP2,AFF2,PPARGC1A,SOX21,PTPRD,SLC25A36,PPP4R3A,SP4,NKAIN2,SYN2,TBL1X,DICER1,FLRT2,MKRN3,LYPD6,MAP3K12,MFF,PRDM10" MicroRNA hsa-miR-595:PITA hsa-miR-595:PITA_TOP PITA 5.22E-15 2.92E-11 1.05E-14 9.68E-14 37 217 "PCDH19,OSBPL8,CEP126,MAP4K3,ZBTB10,CALM1,NRXN3,HECTD1,PUM1,HDAC4,MYEF2,CPEB2,ACSL4,TAOK3,MED12L,FOXF2,SYNCRIP,FUT9,GRIA2,IGF1,MAT2A,CHIC1,AFDN,GPR85,GTDC1,CPEB3,CPEB4,MBD5,PDZD2,SATB2,TPM1,FLRT2,MKRN3,TMEM237,EMSY,PDSS2,RNF146" MicroRNA hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 5.26E-15 2.95E-11 1.06E-14 9.75E-14 55 449 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-5692a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.34E-15 2.99E-11 1.07E-14 9.89E-14 43 289 "WDR35,TXNDC16,ZNF555,PRC1,CD38,STOML1,FEM1B,ZNF585B,DOT1L,GABRA3,ZNF559,SRRM4,ATXN2L,HLF,ZIC5,JAK2,LRP1B,GPR137C,PDE3A,TMOD2,LRP12,PSAT1,SH3KBP1,PPARA,SH3TC2,ENOX1,RBBP6,SLC25A36,TMLHE,CSRNP3,SGK1,HECW1,ZBTB43,ZNF621,TBCEL,ZMAT3,ACTR6,UBE3A,ZNF711,SMARCAD1,ZXDA,HNRNPA3,NETO1" MicroRNA hsa-miR-1273g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-15 3.11E-11 1.12E-14 1.03E-13 59 507 "XKR4,SLC24A4,HACE1,TXNDC16,PHF12,AQP6,CDC14B,PRX,ZNF555,CAMK2G,SLC16A4,CBFA2T2,NRXN3,HINFP,SUSD5,UBXN2A,MYADM,TMEM170A,DNAL1,MTX3,MRNIP,EPB41,KATNAL1,ATP13A4,FUT9,ZNF234,GPR75,KIAA1958,DDX19B,MIER3,KCNN3,CHST6,ZC3H12B,SLC11A2,MINDY2,STK32A,TMEM145,ZNF844,TRIM68,KLHL11,KLHDC8A,ALG9,ATAT1,ATXN2,KANSL3,SEPHS1,MCF2L2,LHPP,SSTR2,ARL10,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,ZNF138,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-4326:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.79E-15 3.24E-11 1.16E-14 1.07E-13 22 72 "C3orf14,C1QTNF3,ARHGDIA,ARSE,CCNT1,LONRF2,CLTC,TMEM184B,RTTN,IGDCC3,FEM1B,ERBB2,FER,SIGLEC8,NFYA,SLC25A36,HSD11B1L,SLC2A5,VPS13A,MLST8,ZNF34,TNS1" MicroRNA hsa-miR-192-5p:TargetScan hsa-miR-192-5p TargetScan 5.82E-15 3.26E-11 1.17E-14 1.08E-13 32 163 "PTCHD1,ALCAM,DPP10,PKP4,DST,CACNA1I,RUNX1T1,IGDCC3,ANKRD44,CTH,GAPVD1,DBT,ALKBH8,CDON,KRBA2,EIF1,PCDH17,LPAR4,PTPRT,ARHGAP36,IL6ST,KCNK3,LIMS1,MMP16,MYO9A,PRKACB,APTX,CPEB4,NKAIN2,DICER1,RICTOR,PHTF2" MicroRNA hsa-miR-215-5p:TargetScan hsa-miR-215-5p TargetScan 5.82E-15 3.26E-11 1.17E-14 1.08E-13 32 163 "PTCHD1,ALCAM,DPP10,PKP4,DST,CACNA1I,RUNX1T1,IGDCC3,ANKRD44,CTH,GAPVD1,DBT,ALKBH8,CDON,KRBA2,EIF1,PCDH17,LPAR4,PTPRT,ARHGAP36,IL6ST,KCNK3,LIMS1,MMP16,MYO9A,PRKACB,APTX,CPEB4,NKAIN2,DICER1,RICTOR,PHTF2" MicroRNA hsa-let-7g-5p:Functional MTI Functional MTI miRTarbase 5.86E-15 3.28E-11 1.18E-14 1.08E-13 47 341 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,DDR1,CRY2,DCAF8,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,TRMO,PDLIM5,CELF1,DISC1,GATM,POLL,FUT10,RABL2A,IL6R,KPNA5,THYN1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,SYT1,KIAA0930,SLC19A3,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1" MicroRNA hsa-miR-372-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.89E-15 3.30E-11 1.18E-14 1.09E-13 46 328 "TMEM132B,SLC24A4,TXNDC16,CDK13,ZBED1,ZNF445,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,FEM1B,PLEKHA1,C8orf37,COQ7,RAB9B,SRCAP,TNRC6A,FUT10,HAS2,DDX19B,CHST6,MITF,DBNL,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,FNBP1,SP4,ADAMTS17,SLC19A3,VWCE,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,ZNF24" MicroRNA hsa-miR-299-5p:TargetScan hsa-miR-299-5p TargetScan 7.77E-15 4.35E-11 1.56E-14 1.44E-13 35 197 "ABR,BRAP,RNF150,CASK,CCAR2,ATP2B2,DST,NSL1,CLOCK,CS,HDAC4,CPEB2,EDNRB,HIPK3,PLXNC1,ELN,DCTN4,IQCG,IQGAP2,RASSF8,C9orf129,RBPJ,MAT2A,PCDH8,CCSER2,GTDC1,ROBO1,RORB,KDM4B,EXOC7,NSD1,PUM2,NR2C2,NAV3,MARCH8" MicroRNA "GTGCCAT,MIR-183:MSigDB" "GTGCCAT,MIR-183:MSigDB" MSigDB 8.36E-15 4.68E-11 1.68E-14 1.54E-13 32 165 "OSBPL8,OGT,PKP4,CHRD,CFL2,SRSF11,CLCN3,QKI,CSNK1G3,KLHL3,RHOBTB1,SACS,CELSR3,BACH2,HECTD2,MBNL1,MEF2C,PDE4D,ING3,USP47,SEMA6D,SMPD3,PPM1E,TET1,LMO3,TCF12,ZFPM2,SLC44A1,TMPO,RIMBP2,TPM1,FRMD6" MicroRNA hsa-miR-193a-5p:TargetScan hsa-miR-193a-5p TargetScan 8.95E-15 5.01E-11 1.79E-14 1.65E-13 33 176 "KCNH8,PCDH10,MARCH3,RUNX1T1,CNTFR,CCDC144A,RASSF2,FGF14,MEX3B,MMADHC,ASPRV1,MEIS1,MMP16,MYO5A,NOVA1,OLA1,PPP5C,EPDR1,RBBP6,RPE,KIAA0895L,BDP1,MPRIP,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ELP5,LAMP5,NETO2" MicroRNA hsa-miR-661:PITA hsa-miR-661:PITA_TOP PITA 8.97E-15 5.02E-11 1.80E-14 1.65E-13 31 155 "UNC5A,PITPNM2,APBA2,SEMA4G,MARK4,NCOA1,EVI5L,TAOK2,ZNF385A,RIMS4,ARHGEF4,DCAF8,RUSC2,DRP2,PHC2,USP21,TPPP3,PPARGC1A,TTBK1,RNF165,BACH2,SYNPO,LRRC75A,MSI1,NEFH,ZNF827,DPF2,STX1B,FAM214B,CUX2,KLC2" MicroRNA hsa-miR-1322:PITA hsa-miR-1322:PITA_TOP PITA 9.08E-15 5.08E-11 1.82E-14 1.68E-13 29 135 "XKR4,HECW2,LRCH2,ARNTL,CACNA2D1,CLTC,GOLGA7,COPS4,BACH2,KCND1,KIF5A,CHIC1,MEIS1,MYO5A,PDE1C,OXR1,SATB1,CSRNP3,PEG10,CDK19,PLCB1,SYPL1,CAMTA1,SLC44A1,FAM155A,PCDH20,TMEM237,CADM2,HRASLS" MicroRNA hsa-miR-574-3p:mirSVR_highEffct hsa-miR-574-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.24E-15 5.17E-11 1.85E-14 1.70E-13 30 145 "ATP2A2,MYOM1,CBR1,CLTC,FAM19A5,SLC4A8,HINFP,USP6NL,FBXL5,GORAB,GALC,INSM1,MN1,GIT1,COL28A1,STRN3,SNRK,USP47,FAM66C,RFX3,RGS3,CCDC82,RXRA,HKDC1,TMCC1,FAM219A,SP2,SYNE2,ATMIN,FIP1L1" MicroRNA hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 9.26E-15 5.18E-11 1.85E-14 1.71E-13 55 455 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-4772-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-15 5.21E-11 1.86E-14 1.72E-13 46 332 "MTA3,SPOP,USP37,BMP7,GYG2,DIS3L,RTTN,HINFP,MATR3,KRBA2,HEYL,IRAK4,MRNIP,IGSF6,MED12L,FGFR1,SEC23B,APOPT1,DBF4,KDM2B,RAB40B,LILRA2,DDX19B,ZNF546,IBA57,METTL21A,GPR155,MAPT,ZNF655,EXOSC10,FITM2,SNRK,MTMR10,NWD1,PGBD4,PEX26,ZNF430,ATF7IP,MAPKBP1,SP2,ZNF621,KLHL7,ALG1,PCDHA6,ZNF106,SSBP2" MicroRNA hsa-miR-548s:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.47E-15 5.30E-11 1.89E-14 1.74E-13 53 427 "KIAA1324,C6orf89,BACH1,CBS,CCNT1,AKAP6,LRIG1,CSNK1E,CTH,GREB1,MYADM,KIAA0586,DBT,YTHDC1,MRO,COQ7,ZNF549,POLR1B,TRMO,GATM,CRCP,GLUL,LUZP2,DDX19B,HLF,ZNF678,CYP27C1,MAPT,MYO6,SFR1,SLC11A2,PTPRB,MRPS18A,SNX22,SGSM1,PTGR2,PREX2,PEX26,FAM126B,DDN,LHPP,SSTR2,NEK4,ALG1,AGTPBP1,TBCEL,USP22,ZMAT3,ZNF610,VLDLR,TBC1D15,ZNF70,GAN" MicroRNA hsa-miR-760:PITA hsa-miR-760:PITA_TOP PITA 1.02E-14 5.70E-11 2.04E-14 1.88E-13 36 210 "LCORL,ARNTL,ADGRB1,CAMK2G,TAOK2,SEC24C,RIMS4,PUM1,WDR20,FAM107B,CPEB2,HEYL,GOLGA7,RAB9B,SRRM1,FGF1,AKAP3,AHDC1,MBNL1,MEIS2,GIT1,SLC11A2,NTRK2,ZNF827,PRKAB2,GTDC1,SGK1,SHMT2,WDR37,CCDC88A,HECW1,STAC2,SMG6,ZBTB38,DPYSL5,ST8SIA2" MicroRNA hsa-miR-361-3p:mirSVR_highEffct hsa-miR-361-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-14 5.73E-11 2.05E-14 1.88E-13 47 346 "PWWP2A,AP2A1,FAM135A,OGT,CCAR2,BLM,DDR1,PTBP2,CAMK2B,ENTPD6,TPP1,DLX1,DMPK,KLHL5,TMEM132E,TMEM35A,EPB41,POMT1,DLL3,TMEM8B,ZBTB49,RASSF8,PIK3AP1,MSR1,PCDH9,PDE1C,PDE1B,LRP12,USP47,PRRT2,MORC4,CARF,PNMA8A,MEG3,SH3GL3,NUBPL,SLC12A4,IFT122,TSPYL2,NAT16,AP4E1,UBE2H,UGT8,TRIM9,EMSY,HPS4,NHSL1" MicroRNA hsa-miR-3180-3p:mirSVR_highEffct hsa-miR-3180-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-14 5.86E-11 2.09E-14 1.93E-13 28 126 "SUGT1P4-STRA6LP-CCDC180,PPFIA3,ZSCAN18,SEC11C,DDR1,RUNX1T1,CABP1,SLITRK5,CYBB,GTF2IRD2,PSD2,FAM107A,MEIS1,NPTX2,ZNF827,NALCN,EXOSC10,VSTM2L,LGI3,SLC22A4,SMARCC2,PRRT1,ATP6V0E2,ANKS1B,DHX33,CASC15,ADAMTS10,JPH3" MicroRNA hsa-miR-4433a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-14 5.89E-11 2.10E-14 1.94E-13 49 373 "SLC24A4,TXNDC16,SMIM17,AMH,APAF1,ZNF583,ISPD,NDST3,NRXN3,CS,SUSD5,CTH,USP6NL,GAPVD1,RASSF2,LONRF1,TMEM170A,ELMSAN1,ZNF549,ZNF585B,FAM120B,MTHFD2,GPR75,GLUL,LUZP2,LILRA2,ZBTB49,KCNJ5,STMN1,CHST6,PPM1L,MMP17,MPP2,SFR1,ZNF713,CCSER2,PLEC,MTMR10,ZNF844,CEP97,MSANTD2,SEMA6D,PREX2,SLC2A5,NEK4,MGRN1,SSBP2,ZNF610,ZFAND5" MicroRNA hsa-miR-6734-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-14 6.15E-11 2.20E-14 2.02E-13 37 222 "AS3MT,AK2,ASGR1,DDR1,LURAP1,LRRFIP1,NUMBL,B4GALT6,CRY2,PDE4DIP,PLCXD3,CYBB,TMCC2,USP3,OPTN,ERBB2,ANKMY1,REEP2,CELF1,HHIPL1,SRRM4,LYVE1,TCERG1,PADI2,HMGCR,MN1,MYO5A,POLG,PRKCB,BCAS3,MSANTD2,DPF2,ELP2,ZFP30,PKNOX2,ZSCAN29,NSFL1C" MicroRNA hsa-miR-4755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-14 6.27E-11 2.24E-14 2.06E-13 43 295 "APAF1,ARHGDIA,CBS,NUMBL,AKAP6,CSNK1E,UBXN2A,GREB1,MYADM,DBT,EXOG,POLR1B,TRMO,CRCP,IRAK3,DDX19B,TJAP1,CYP27C1,MAN2A2,MYO6,PIK3R1,PPARA,MINDY2,ZNF793,SGSM1,RPS6KA2,PTGR2,PEAR1,SH3BP2,R3HDM2,PEX26,EPN2,TRIM67,FAM126B,SSTR2,SEPT8,ALG1,SIN3B,UBTF,ZNF28,ZNF70,NETO2,GAN" MicroRNA hsa-miR-4469:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-14 6.48E-11 2.31E-14 2.13E-13 44 308 "TMEM132B,ARRB1,ARSE,BACH1,CA8,CCNT1,STOML1,QKI,TOGARAM2,PITPNM3,UBXN2A,PLCXD3,CYBB,TMEM170A,SPATA2,RUSC2,TMCC2,HEYL,EMX2,FER,GABRG2,GPR75,ZNF638,KIAA1958,SHISA6,KCNQ3,LSAMP,KSR2,PPP1R1A,MTMR10,PTPRG,GTDC1,DIP2A,ARC,IQCE,NSD1,ZMAT3,KCNK12,AMZ1,ZNF225,SLC30A3,URM1,GAN,JPH3" MicroRNA hsa-miR-3178:mirSVR_lowEffct hsa-miR-3178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-14 7.04E-11 2.51E-14 2.31E-13 33 178 "AMH,LRFN1,AQP6,ARHGDIG,ASGR1,MARK4,EVI5L,COX4I1,CREM,SPATA2,DMPK,EPHB1,ZNF391,BAIAP2,POLK,AGAP3,ZNF274,TTBK1,MUM1,INSM1,MSI1,NNAT,FXYD1,MAPK4,RIPOR1,NKAIN1,MAPK12,RASA3,DHX30,MCF2L2,CAMTA2,IQCE,NEIL2" MicroRNA hsa-miR-181b-5p:Functional MTI Functional MTI miRTarbase 1.30E-14 7.26E-11 2.59E-14 2.38E-13 49 375 "MTUS1,HECW2,OSBPL8,HFM1,ARRB2,SEC24C,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,MTX3,FSD1L,FAM13A,ELN,STX2,FGFR1,IQCG,GRIA2,DIDO1,ZDHHC15,IPO5,NCOA7,BLOC1S2,PPP2R5E,ZNF844,PBRM1,MEG3,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,CPEB4,ZNF667,ZNF415,TMCC1,SPP1,UNC5B,KLHL7,PRRC2C,SLC35G2,SIRT1,TUBB2A,VSNL1,ZNF781,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-490-3p:PITA hsa-miR-490-3p:PITA_TOP PITA 1.37E-14 7.64E-11 2.72E-14 2.51E-13 29 137 "RALGAPA1,MAP4K3,CERS5,ARHGAP33,FOXN3,MAP4K4,CNR1,AHCTF1,ERC2,DBN1,EVL,ERGIC3,GFRA2,PCDH17,BACH2,RBPJ,IBA57,MID1,MSI1,CNOT4,TMEM104,OXR1,GTDC1,CHD9,FAM219A,SOX11,SYT1,TP53BP1,NR2C2" MicroRNA hsa-miR-7703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-14 7.94E-11 2.83E-14 2.61E-13 56 474 "XKR4,SLC24A4,HACE1,KIAA1324,TXNDC16,PHF12,AQP6,CDC14B,JAZF1,ZNF555,SLC16A4,ZNF445,NRXN3,CLOCK,SUSD5,UBXN2A,TMEM170A,DNAL1,MTX3,MRO,EPB41,ATP13A4,ANKFY1,TRMO,FUT9,ZNF234,COPS8,GPR75,KIAA1958,AGBL5,KCNN3,CHST6,ZC3H12B,SLC11A2,ZFYVE21,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ALG9,ATAT1,SEPHS1,FAM126B,MCF2L2,ARL10,PPIL6,SSBP2,ZNF610,UBC,USP1,TBC1D15,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 1.43E-14 8.00E-11 2.85E-14 2.62E-13 43 297 "ADGRB2,CBS,SCARB1,ZBED1,IGDCC3,CS,PUM1,KIAA0408,MYADM,DNAL1,DBT,RUSC2,TOM1,USPL1,SRRM1,TUBA1B,RACK1,ATP5PD,TMEM8B,ATXN2L,ELOVL5,ZIC5,IPO5,CHIC1,MKLN1,NFIX,OPRL1,PALM,PKD1,DEF8,RAD51D,TMCC1,TRERF1,SEPT8,CRTC1,WBP2,STXBP4,UGT8,MGAT5B,POLR3H,AMZ1,TUBA1A,ITM2C" MicroRNA hsa-miR-423-5p:PITA hsa-miR-423-5p:PITA_TOP PITA 1.44E-14 8.07E-11 2.87E-14 2.64E-13 27 118 "ASIC1,ACHE,ZNF608,ADGRB1,HAP1,ZNF385A,RIMS4,PUM1,LYPD1,EGR3,AGAP2,AGAP3,AHDC1,RNF165,BACH2,NFIX,NPTX1,NTRK3,PDE1B,EPB41L4B,PKIA,TMEM260,SMARCC2,ERC1,PLCB1,SYP,SMG6" MicroRNA hsa-miR-25-3p:Functional MTI Functional MTI miRTarbase 1.44E-14 8.08E-11 2.87E-14 2.65E-13 59 518 "CASKIN1,ATP2A2,TMEM184B,SNPH,DCTN1,DNM1L,MRO,EIF4G2,PLEKHA1,EIF1,ERBB2,DENND4A,NRN1,PRMT5,FECH,SEMA4D,MPP6,ACSS1,TUBGCP4,KIAA1958,PRRC2B,LILRA2,TPPP,AGBL5,SMAP1,EID2B,ZIC5,RBPJ,IL6ST,MBD1,CNOT4,ZDHHC8,CCSER2,ZFYVE21,KCTD15,PURG,TATDN3,MTMR10,REV3L,RGS3,SLC25A36,ROBO1,FBXW7,FNIP1,CPEB3,SLC12A4,BTBD7,ATF7IP,CPEB4,FNBP1,SOX11,MCF2L2,ITPRID2,STXBP1,ANKRD24,CABIN1,ZNF346,ZNF24,MFF" MicroRNA hsa-miR-517a:mirSVR_highEffct hsa-miR-517a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-14 8.16E-11 2.90E-14 2.67E-13 35 201 "FMNL2,ELFN2,ALCAM,LURAP1,B4GALT6,ABI3BP,ZNF521,CS,GAPVD1,KIF26A,DBN1,SACS,NR1D2,EGFR,DLC1,PRMT5,POLR1B,ARFIP1,AHDC1,GGT7,GHR,HPGDS,MSL1,JAK2,STMN1,NUDT11,MBD5,TMCC1,TMEM150C,DOCK9,AP4E1,SLC44A1,TNS1,USP1,EML6" MicroRNA hsa-miR-182-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.49E-14 8.34E-11 2.96E-14 2.73E-13 33 179 "ADCY6,BARD1,SLC25A14,CLOCK,PITPNM3,PCOLCE2,TUBD1,NRN1,TUBA1B,FOXF2,FOXO3,CHL1,MALT1,TNRC6A,PPM1L,MITF,NPTX1,PCDH8,PFKFB3,PIK3C2A,RAD17,FBXW7,CASC3,SLC11A1,SMARCD3,ANKRD36,SIN3B,SATB2,TIAM1,TP53BP1,RPL7L1,TCEAL7,EVI5" MicroRNA hsa-miR-662:mirSVR_highEffct hsa-miR-662:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-14 9.23E-11 3.28E-14 3.02E-13 30 148 "KCNH8,ADORA1,CLDN10,METTL6,SLITRK5,CYBB,HEPH,PARD6A,NYAP1,ZNF461,EFCAB2,ZNF605,KDM2B,LPAR4,GRIK4,AGBL5,LYRM9,PRIMPOL,NDUFS7,RDX,ZMAT4,ZNF532,ARMH4,SGK1,TEX2,TMEM150C,SIN3B,ANKRD20A2,RICTOR,DHX33" MicroRNA hsa-miR-504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-14 9.24E-11 3.28E-14 3.02E-13 50 391 "ABCF1,CLK4,XKR4,RNF157,ESYT2,DOCK11,ISPD,AKAP5,DBT,KRBA2,HEYL,OPTN,TUBD1,SEC23B,CINP,SPECC1,GPR75,GLUL,LILRA2,GRB10,KAT7,SHISAL1,IBA57,LIMS1,GPR155,MKLN1,OLA1,ZNF655,PKM,GPSM2,PIGG,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,ANKRD36,ERC1,CDK19,SSTR2,MPRIP,KLHL7,ALG1,FBXW11,GPR161,ZNF106,ZNF74,ZNF154,TIGD6,RNF170" MicroRNA hsa-miR-1251:mirSVR_highEffct hsa-miR-1251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-14 9.42E-11 3.35E-14 3.08E-13 51 405 "KCNH8,MTUS1,UPRT,PPP4R4,SYNJ2,NAE1,VXN,CNOT8,LHX2,SLC35F1,KATNAL2,ARHGAP24,KIAA0586,MFAP3L,LRRC17,TUBB3,KAT8,ZNF589,UBE2E3,POMT1,SPECC1,ERGIC3,DOT1L,GHDC,MTHFD2,LRRC37A6P,SULT1C4,PPARGC1A,BRD8,RASSF8,AGBL5,ICA1,KCNB1,STMN1,MYO9A,NPTX2,NUCB2,RETREG1,SNRK,C1orf109,RYR3,PEX26,TACR1,CYB561A3,ERCC6L2,ZNF74,NAV3,PDSS2,IFT88,NETO1,RNF146" MicroRNA hsa-miR-651:PITA hsa-miR-651:PITA_TOP PITA 1.70E-14 9.49E-11 3.37E-14 3.10E-13 32 169 "RALGAPA1,SEMA6A,SLC4A4,SRSF11,CNTN1,PLCXD3,PUM1,DPYSL2,SUCO,SESN1,GPR34,FAM19A2,BACH2,IGF1,ZIC5,LAMP2,NRCAM,PMP22,TRHDE,MTMR10,SCP2,CPEB4,CLASP2,CBX5,TSC1,UBE2H,ZBTB38,RNF103,ADAMTS9,NAV3,RGS7BP,FZD3" MicroRNA hsa-miR-331-3p:Functional MTI Functional MTI miRTarbase 1.86E-14 1.04E-10 3.69E-14 3.40E-13 51 406 "AP2A2,ZNF608,STX16,NRP2,CAMK2G,SLC25A14,CLDN10,ARHGEF1,TAOK2,QKI,EARS2,FBXL5,SEC16A,TOM1,EIF4G2,EPB41L2,ERBB2,SCML2,APOPT1,USP21,GFER,GGT7,PRRC2B,PTPRT,MIER3,TJAP1,ITPKB,MAP4,MARK3,HNRNPM,NELL2,OPRL1,PDPK1,DEF8,PTPN13,RDX,CARF,HES6,SH3BP2,AMBRA1,SEC31A,SPTAN1,SPTB,SS18,ZC3H4,EXOC7,SMG6,SIRT1,KLC2,POLR3H,STOX2" MicroRNA hsa-miR-3135:mirSVR_highEffct hsa-miR-3135:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-14 1.04E-10 3.70E-14 3.41E-13 41 274 "AMPH,SLC4A4,MTMR7,C1orf52,SLC4A8,MATR3,SV2B,DOCK2,RGS17,NBEA,FYB1,TUBA8,LNX1,ADGRA3,PLCD4,FAM95B1,IL6R,DNHD1,MAPKAP1,EPB41L4B,SNRK,MTMR10,GTDC1,SLC25A36,TMLHE,FBXW7,TRAPPC13,SCN8A,DHX30,FAM126B,KDM3A,CAMTA1,ZEB1,PUM2,GPRIN3,TK2,SLC35A4,CFAP298,ZBTB14,ZNF189,CPNE4" MicroRNA hsa-miR-921:PITA hsa-miR-921:PITA_TOP PITA 1.93E-14 1.08E-10 3.82E-14 3.52E-13 26 110 "ADRB2,RTL9,MAP4K3,ADGRB3,CACNA2D2,FOXN3,LRRC3B,TMEM121B,ADAMTS6,HAS2,MIER3,HSF2,CHIC1,MEIS2,KANSL1,TMEM260,NCBP3,CCDC88A,SNCA,FAM219A,CDK19,LMO3,NKAIN2,ADGRL3,NR2C2,HNRNPA3" MicroRNA hsa-miR-676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-14 1.08E-10 3.82E-14 3.52E-13 26 110 "TAOK1,PARG,TNRC6C,IPCEF1,UBXN2A,EDIL3,FCF1,SCML2,PCYOX1,MXI1,NPTX1,FAM98B,CCSER2,POLG,PTPRN2,ZNF793,RAP1GDS1,ZDHHC14,GALNT10,LIMCH1,PEG10,DIP2A,TBL1X,ASXL3,PRDM10,PHTF2" MicroRNA "AGCATTA,MIR-155:MSigDB" "AGCATTA,MIR-155:MSigDB" MSigDB 1.98E-14 1.11E-10 3.92E-14 3.61E-13 28 129 "FAM135A,BACH1,QKI,CSF1R,BOC,HDAC4,DYNC1I1,C3orf18,PSIP1,KCNN3,LRP1B,MEIS1,NFIX,NOVA1,PCDH9,GPR85,STRN3,PKIA,WBP1L,SATB1,FBXO11,SLA,SMARCA4,SOX11,SYPL1,CAMTA1,TRIM2,SGK3" MicroRNA "ATGTCAC,MIR-489:MSigDB" "ATGTCAC,MIR-489:MSigDB" MSigDB 1.99E-14 1.12E-10 3.95E-14 3.64E-13 23 84 "PCDH10,NCOA1,BMP7,CLOCK,CELF1,GPD1,ADAMTS13,BACH2,LRRC75A,IPO5,NOVA1,NTRK3,PDE4D,PURG,OXR1,RBBP6,BAALC,HUNK,SGK1,SP4,NSD1,XPO1,ST8SIA2" MicroRNA hsa-miR-1207-5p:Functional MTI Functional MTI miRTarbase 2.23E-14 1.25E-10 4.42E-14 4.07E-13 42 288 "ELFN2,RNF157,CPNE5,HCN2,LONRF2,CSF1,PITPNM3,FAM131B,TM9SF4,IP6K1,HEYL,IRAK4,CELF1,CPLX1,AHDC1,GFER,FUT10,CACFD1,ZNF496,ZNF546,KCNK3,MAP4,PPM1L,TBC1D25,PDE3A,PKD1,POLR2F,NCR3LG1,TMEM145,SARS,MYH15,SOX11,SP2,LHPP,SSTR1,USP22,PUM2,NACC2,CBX5,DPYSL5,ITM2C,GAN" MicroRNA hsa-miR-5690:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-14 1.27E-10 4.48E-14 4.13E-13 37 227 "AS3MT,SLC24A4,TXNDC16,APAF1,AQP6,CDC14B,ZNF583,SLC16A4,CBFA2T2,NRXN3,ENTPD4,IPCEF1,UBXN2A,MYADM,ELMSAN1,FBXL5,MRNIP,ZNF585B,ZNF589,SMC2,DOT1L,GPR75,PRRC2B,BVES,AGBL5,IBA57,KCNJ5,KLHL23,TTC13,SLC25A36,NCBP3,SEPHS1,KIAA1107,TRIM2,ZNF154,ACTR3B,RNF146" MicroRNA hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 2.32E-14 1.30E-10 4.59E-14 4.22E-13 55 465 "FZD9,SORCS2,ZNF578,TAOK1,ATP1B3,BACH1,LDHD,ZBED1,DIS3L,CLCN3,ZNF385A,ENTPD4,SOCS5,UBXN2A,DNAL1,NR1D2,SLC12A6,DPYSL2,APH1A,IRAK4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,GRB10,HAS2,GPR155,MBNL1,PDPK1,TMEM38A,ZNF426,PRKACB,RBBP6,ZNF532,C12orf49,SBF1,HSPA4L,KIF13A,SP2,STAC2,SATB2,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA "ACTACCT,MIR-196A:MSigDB" "ACTACCT,MIR-196A:MSigDB" MSigDB 2.43E-14 1.36E-10 4.81E-14 4.43E-13 28 130 "PCDH19,DOC2A,MAP4K3,GAS7,IGDCC4,CASK,CHRD,BACH1,PCYT1B,PPP1R16B,PPP6R2,LRRC17,DDX19B,LRP1B,NME4,ZNF655,SCHIP1,RDX,WDR37,TRERF1,SOX11,LARP4,DICER1,NR2C2,VSNL1,RICTOR,SOCS4,GAN" MicroRNA hsa-miR-768-5p:PITA hsa-miR-768-5p:PITA_TOP PITA 2.43E-14 1.36E-10 4.81E-14 4.43E-13 28 130 "LRFN1,SYNJ1,VXN,SRSF11,FOXN3,CNTFR,FAM171B,YTHDC1,CHRDL1,PHC2,EPB41,LYVE1,FICD,ZIC5,KITLG,MITF,NRCAM,NTRK3,PDE1B,PLCL1,PMP22,PTK2,DPF2,ZFHX4,SYT1,FRYL,SMARCAD1,KAT6A" MicroRNA "ACTACCT,MIR-196B:MSigDB" "ACTACCT,MIR-196B:MSigDB" MSigDB 2.43E-14 1.36E-10 4.81E-14 4.43E-13 28 130 "PCDH19,DOC2A,MAP4K3,GAS7,IGDCC4,CASK,CHRD,BACH1,PCYT1B,PPP1R16B,PPP6R2,LRRC17,DDX19B,LRP1B,NME4,ZNF655,SCHIP1,RDX,WDR37,TRERF1,SOX11,LARP4,DICER1,NR2C2,VSNL1,RICTOR,SOCS4,GAN" MicroRNA hsa-miR-1234:mirSVR_lowEffct hsa-miR-1234:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.49E-14 1.39E-10 4.92E-14 4.53E-13 52 423 "ASPHD1,PPFIA3,CDK10,ATP6V0A1,SRSF11,SRP14-AS1,RHOBTB1,EDN3,OPTN,CELSR3,APH1A,EIF1,OLFM1,SLC37A3,ERGIC3,BRSK1,USP19,PPARGC1A,TNRC6A,LOXL3,GPD1,TDRKH,ADAMTS13,ATE1,AGBL5,LRRC75A,LIMS1,OGG1,PKD1,NLE1,NKAIN4,MAPK4,CCDC82,CCDC102B,TCP11L1,LRRK2,MEG3,TRAPPC13,FRMPD1,CHD9,SEPHS1,INAVA,SEPT8,TMPO,KCNE5,TSN,ZKSCAN5,SGK3,OSBP2,SLC30A3,SEMA3B,CASC15" MicroRNA hsa-miR-376a:PITA hsa-miR-376a:PITA_TOP PITA 2.70E-14 1.51E-10 5.33E-14 4.90E-13 35 205 "OSBPL8,PITPNM2,SLC4A4,ATP2A2,SLC25A14,SEPT7,QKI,CSNK1G3,FAM131B,WDR20,GRIN3A,KHDRBS3,PCDH17,FERMT2,GRIK5,PDE4B,LRP12,ELOVL2,ROBO1,SALL1,PPM1E,SHC4,CHD9,FBXO11,TET1,MBD5,CDK19,ITPRID2,LARP4,CUX2,TIAM1,WIPF1,CELF4,NAV3,PPP1R3F" MicroRNA hsa-miR-376b:PITA hsa-miR-376b:PITA_TOP PITA 2.70E-14 1.51E-10 5.33E-14 4.90E-13 35 205 "OSBPL8,PITPNM2,SLC4A4,ATP2A2,SLC25A14,SEPT7,QKI,CSNK1G3,FAM131B,WDR20,GRIN3A,KHDRBS3,PCDH17,FERMT2,GRIK5,PDE4B,LRP12,ELOVL2,ROBO1,SALL1,PPM1E,SHC4,CHD9,FBXO11,TET1,MBD5,CDK19,ITPRID2,LARP4,CUX2,TIAM1,WIPF1,CELF4,NAV3,PPP1R3F" MicroRNA hsa-miR-379:PITA hsa-miR-379:PITA_TOP PITA 2.76E-14 1.55E-10 5.46E-14 5.03E-13 22 77 "HECW2,MTMR2,MAGI1,IGDCC3,EDN1,EIF4G2,ERBB4,UBE2E3,PCDH17,RAB30,CACFD1,MAP4K5,IDH3A,KIF5A,MINDY2,RET,HSPA4L,CCDC88A,CDK19,MMS19,ADGRL3,TCF4" MicroRNA hsa-miR-339-5p:mirSVR_highEffct hsa-miR-339-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.80E-14 1.57E-10 5.53E-14 5.09E-13 58 511 "NCKAP5,PLEKHH1,PTCHD1,OGT,PPFIA3,SFMBT2,CCAR2,CHID1,ZNF599,CFLAR,IL33,LURAP1,NFS1,ARHGEF2,LARGE1,NRXN3,SUMF2,DNAJB6,EMX2,EPHB1,RACK1,UFM1,CELF1,ZNF559,LYVE1,POLL,GPD2,TDRKH,PCLO,GRIK4,FAM19A2,NNAT,NOVA1,NUCB2,PDCD2,FAM216A,ELOVL2,TMEM260,CEP97,GAL3ST4,UBR7,CARF,KIRREL1,SUPT20H,SLA,ARHGEF40,SLC11A1,VPS13A,FRYL,MTMR14,NPL,METTL3,UBE3A,ZBTB14,GDPD5,STOX2,HPS4,FAM219B" MicroRNA hsa-miR-1302:PITA hsa-miR-1302:PITA_TOP PITA 2.90E-14 1.62E-10 5.72E-14 5.27E-13 30 151 "NDRG2,FMNL2,TRMT9B,MARK4,SLC4A4,ATP2B2,CAMK2G,USP6,AKAP6,SLC35F1,DCAF8,C2CD2L,PTK2B,IQGAP2,TNRC6A,MIER3,STMN1,KITLG,NNAT,CNOT4,RETREG2,FBXW7,FBXO11,ANKFN1,ERC1,CDK19,TRPS1,UBE3A,VSNL1,MAP3K12" MicroRNA hsa-miR-4524a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-14 1.64E-10 5.79E-14 5.33E-13 44 316 "ABCF1,AS3MT,TEX22,SFMBT2,ARHGDIA,ARSE,LONRF2,CCPG1,TBRG4,RTTN,SEC14L5,TMEM170A,SPATA2,SGSM2,DNAH9,RGS17,TUBD1,SCARA3,PCYOX1,SRRM4,SRCAP,PPARGC1A,CRCP,FUT10,ZDHHC15,SCIN,IBA57,MBD1,NPTX1,GPR173,SMIM7,MINDY2,KANSL1,PKIA,MTMR10,FIGN,ALG9,USP22,TMEM9,TBC1D15,ZNF74,LYPD6,ZNF177,TMEM198" MicroRNA hsa-miR-1291:PITA hsa-miR-1291:PITA_TOP PITA 2.98E-14 1.67E-10 5.89E-14 5.42E-13 28 131 "MTUS1,LRFN1,USP37,ADGRB1,HAP1,SH2B1,DBN1,C2CD2L,DYNC1I1,TNK2,AGAP3,BRSK1,ATXN2L,ELOVL5,LRRC75A,KCNN3,MEF2C,SDK2,TMEM260,PTPRD,FAM214B,SLC8A1,TSPYL2,EXOC7,TAL1,FBXW11,TIAM1,RELL2" MicroRNA hsa-miR-8079:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-14 1.71E-10 6.02E-14 5.54E-13 26 112 "AS3MT,SFMBT2,ARSE,PDE4DIP,MYADM,SUCO,APOPT1,MSANTD4,SRCAP,GRB10,RASSF8,HAS2,MAN2A2,LYPLAL1,CHST6,MYO5A,OCRL,ZNF426,GSTCD,ROBO1,CSRNP3,ANKRD36,ZNF34,RICTOR,MPPE1,TMEM63C" MicroRNA hsa-miR-1305:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.31E-14 1.85E-10 6.53E-14 6.01E-13 34 195 "RNF150,TNRC6C,CALM1,RIMS4,TMTC1,FSD1L,SLC37A3,MSANTD4,KCNMB4,IGF1,ZNF678,KCNB1,KPNA5,NPTX1,SH3KBP1,PPARA,SH3TC2,GTDC1,FNDC3A,SLC8A1,TET1,FAM208A,ARL10,ASXL3,LRRC8A,TUBB2A,UBE2H,VLDLR,ZNF24,KCNT2,ZNF225,SLC30A4,ZXDA,PRDM10" MicroRNA hsa-miR-10b:PITA hsa-miR-10b:PITA_TOP PITA 3.36E-14 1.88E-10 6.63E-14 6.10E-13 32 173 "TMEM132B,ZNF608,KCTD16,DOCK11,CAMK2G,MAGI1,NCOR2,RIMS2,AGAP3,ANKFY1,CHL1,TMEM121B,RNF165,BACH2,SMAP1,NFIX,CNOT4,XRN1,PURG,TMEM260,DPF2,FIGN,KCTD17,MBD5,TRIM2,TIAM1,CSMD1,KAT6B,FLRT2,POLR3H,SLC30A4,WNK3" MicroRNA hsa-miR-10a:PITA hsa-miR-10a:PITA_TOP PITA 3.36E-14 1.88E-10 6.63E-14 6.10E-13 32 173 "TMEM132B,ZNF608,KCTD16,DOCK11,CAMK2G,MAGI1,NCOR2,RIMS2,AGAP3,ANKFY1,CHL1,TMEM121B,RNF165,BACH2,SMAP1,NFIX,CNOT4,XRN1,PURG,TMEM260,DPF2,FIGN,KCTD17,MBD5,TRIM2,TIAM1,CSMD1,KAT6B,FLRT2,POLR3H,SLC30A4,WNK3" MicroRNA hsa-miR-215-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-14 1.94E-10 6.81E-14 6.27E-13 27 122 "TEX22,USP37,SFMBT2,ZBTB10,COL9A1,ZSCAN23,DBT,OPTN,TENM1,TUBD1,TPPP,KAT7,GPSM2,STRN3,PIGG,MTMR10,HSPA4L,BDP1,SEPT3,KLHL7,KIAA0930,AP4E1,ZNF34,ZNF106,ZNF74,SPIRE1,SLC38A1" MicroRNA hsa-miR-668:PITA hsa-miR-668:PITA_TOP PITA 3.48E-14 1.95E-10 6.85E-14 6.31E-13 23 86 "USP37,CACNA1A,CAMK2G,ARMC8,GOLGA7,EMX2,EPB41,TOX3,GNAO1,PRRC2B,ATXN2L,NEGR1,IGF1,MAPT,KITLG,CNOT4,PCDH9,SP4,CDK19,CLASP2,POLR3H,SMARCAD1,NAV3" MicroRNA hsa-miR-197:PITA hsa-miR-197:PITA_TOP PITA 3.49E-14 1.95E-10 6.86E-14 6.31E-13 30 152 "USP31,UNC5A,PCDH19,SEMA6A,CBLN1,MTX3,GRIN3A,DNM1,EBF1,EYA1,TAOK3,AGAP2,GRIA2,SMAP1,KCND2,STXBP5,MBNL1,TMEM145,FBXW7,PPM1E,NLGN1,CCDC88A,SOX11,PEG10,SS18,SYN1,TAL1,DOCK9,UBE3A,FZD3" MicroRNA hsa-miR-526b:PITA hsa-miR-526b:PITA_TOP PITA 3.49E-14 1.95E-10 6.86E-14 6.31E-13 30 152 "MTUS1,ZBTB10,SLC4A4,CLIP3,KIAA0408,ALKBH8,POM121,CPEB2,EPHB1,NRN1,DLC1,OGA,GABRG2,TDRKH,ZHX1,FRMD3,IGF1,KTN1,MAP2,MKLN1,GPR137C,ZNF827,XRN1,STRN3,RELN,ZFHX4,ROBO1,ARX,PRDM10,SOCS4" MicroRNA hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 3.88E-14 2.17E-10 7.62E-14 7.02E-13 39 255 "EMILIN3,OSBPL8,ALK,TNRC6C,PRX,PLA2G4C,UBXN2A,ARHGAP32,NR1D2,FRY,PHF20L1,EGFR,IRAK4,ACSL4,RACK1,POLK,CHL1,TJAP1,STMN1,LIFR,LIG4,CCSER2,MTMR10,SH3TC2,FAT4,KLHL11,SETD5,GSTCD,YY1AP1,FAM81A,SAMSN1,STAU1,ANKRD28,CRTC1,SIRT1,ZNF711,PARP11,RTN4,FXR1" MicroRNA hsa-miR-4446-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-14 2.22E-10 7.80E-14 7.18E-13 37 231 "RNF150,MTA3,SPOP,SEMA4G,BCL7A,CACNA1G,CACNA2D1,RGS6,TBC1D5,DMD,RCAN1,KLHL5,CELSR3,FAM13A,TBC1D16,AMOTL2,SRCAP,GLUL,KCNMB4,TPPP,NEGR1,RBPJ,NOVA2,GLIPR1L2,PTPRE,MARCH1,RORB,KIF21A,BTBD3,SEPHS1,SLC11A1,ZBTB43,TNS1,TOM1L2,ZNF177,SLC38A1,DPF3" MicroRNA hsa-miR-1236-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-14 2.22E-10 7.80E-14 7.18E-13 38 243 "SPOP,PRX,GPR146,DIS3L,CLTC,SH2B1,PITPNM3,UBXN2A,PLCXD3,GAPVD1,CENPL,C2CD2L,RCAN1,EPB41,ZNF391,TBC1D16,TMEM175,CELF1,NSG1,GABRG2,ZNF638,IBA57,NOVA2,NPTX1,KSR2,TMOD2,KCTD15,PLCL1,PKIA,CNNM2,PTPRN2,EPN2,LIMCH1,KLHL4,ZEB1,KAT6B,XPO1,PRDM10" MicroRNA hsa-miR-486-5p:TargetScan hsa-miR-486-5p TargetScan 4.28E-14 2.39E-10 8.40E-14 7.74E-13 27 123 "NCKAP5,MTA3,HECW2,MARCH4,DYNLL1,CLDN10,ARMC8,PLXNA4,GAPVD1,ELMSAN1,GRIN3A,CELSR3,CSPG5,GABRB3,INPP5K,MYLK2,IGF1,KCNQ3,MARK1,NFYA,PDE4A,PIK3R1,CNKSR2,BTBD3,PRRC2C,NR2C2,FLRT2" MicroRNA hsa-miR-339-5p:TargetScan hsa-miR-339-5p TargetScan 4.43E-14 2.48E-10 8.69E-14 8.00E-13 29 143 "PLEKHH1,PDZD4,CDK13,NRP2,MTMR3,HAP1,RUNX1T1,PPP6R2,JAKMIP2,ERBB4,FHL1,FLT1,BRSK1,PCDH17,LYVE1,PRUNE2,ARHGAP36,GPR62,SCAMP5,NNAT,NOVA1,PDE4D,PFKFB3,PURG,CNNM2,ELOVL2,RORB,COPZ1,NFASC" MicroRNA hsa-miR-508-3p:PITA hsa-miR-508-3p:PITA_TOP PITA 4.43E-14 2.48E-10 8.69E-14 8.00E-13 29 143 "FMNL2,CDC14B,NCOA1,NUMB,SEPT7,CFL2,CNN3,ABI3BP,PLCXD3,PCOLCE2,NCALD,MSTN,GRIA2,MITF,PDE4D,PIK3R1,TRHDE,LRP12,MINDY2,SATB1,CPEB3,ABLIM3,PPP4R3A,LMO3,CLASP1,SYNE1,TSC1,RNF103,PHTF2" MicroRNA hsa-miR-532-3p:TargetScan hsa-miR-532-3p TargetScan 4.54E-14 2.54E-10 8.90E-14 8.20E-13 38 244 "MTA3,PDZD4,BCAS1,EIF4G3,P2RX6,DGKI,CDH2,HECTD1,LETMD1,SEC31B,CSF1,IPCEF1,DRP2,CELSR3,ETV1,HPCAL4,PPARGC1A,CBX1,PTPRT,NXPH3,NEGR1,MBD1,PPM1L,MMP16,NFIX,NPTX1,PIGG,DPF2,CYB561D1,PRCD,MYO18A,AMBRA1,NMNAT2,PEG10,NFASC,GPRIN3,GDPD5,MSRB3" MicroRNA hsa-miR-6134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-14 2.57E-10 9.01E-14 8.30E-13 47 360 "ABCF1,HACE1,PTBP2,CBS,CFL2,SUMF2,CRY2,PITPNM3,RUBCN,GAPVD1,DNAL1,TMTC1,MRO,FGFR1,NEURL4,MTHFD2,CSDC2,CRCP,SHISA6,IGF1,TBC1D25,NLE1,RETREG2,DIRAS2,NCR3LG1,MTMR10,CEP97,RAP1GDS1,C12orf49,PGBD4,FAM161B,NCBP3,AMBRA1,EPN2,SP2,AGTPBP1,CRTC1,WBP2,TUBB2A,BCL2L13,LAT2,ZNF17,ZNF28,EVI5,CIAPIN1,PARP11,ZDHHC20" MicroRNA hsa-miR-483-5p:mirSVR_highEffct hsa-miR-483-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.70E-14 2.63E-10 9.22E-14 8.49E-13 32 175 "ALCAM,MAGEE2,ARHGDIA,CLCN3,SUMF2,DOCK4,TCAF1,DAPK1,KIF19,DLX1,SLC25A18,SLC43A2,MRPL37,RRAGB,ADGRV1,FDFT1,TMEM107,LRRC37A6P,GPT2,DIDO1,DNHD1,MAPK3,NCBP3,ANKRD6,ATF7IP,RCOR3,IQSEC2,IQCE,SATB2,PCDHB9,TIAM1,RUSC1" MicroRNA hsa-miR-1245a:Functional MTI Functional MTI miRTarbase 4.79E-14 2.68E-10 9.38E-14 8.64E-13 26 114 "AS3MT,SFMBT2,ARSE,PDE4DIP,MYADM,SUCO,APOPT1,MSANTD4,SRCAP,GRB10,RASSF8,HAS2,MAN2A2,LYPLAL1,CHST6,MYO5A,OCRL,ZNF426,GSTCD,ROBO1,CSRNP3,ANKRD36,ZNF34,RICTOR,MPPE1,TMEM63C" MicroRNA hsa-miR-3140-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-14 2.95E-10 1.03E-13 9.52E-13 27 124 "AS3MT,MTUS1,PCDH19,ARRB1,CCDC74A,IGDCC3,LRIG1,GPRASP1,MRO,ERBB2,FOXF2,SRCAP,PCDH17,PRRC2B,MIER3,RBPJ,MKLN1,NPTX1,MTRF1L,ZSCAN2,ZDHHC14,C12orf49,ROBO1,PEX26,LIMCH1,RBM26,ZNF711" MicroRNA hsa-miR-671-3p:mirSVR_lowEffct hsa-miR-671-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.40E-14 3.02E-10 1.06E-13 9.74E-13 40 270 "METAP1D,XKR4,LTBP4,VAT1L,TTLL9,KSR1,EPS15L1,SMARCAL1,ZFP28,DMTF1,DPYSL2,EDN1,PHF20L1,SUGP2,USPL1,FGF1,FLT1,HHIPL1,CRCP,GRB10,MAN1B1,C9orf129,KIT,CHIC1,NTRK2,TMEM260,TRAPPC13,ATXN7,FOXRED1,SYBU,SLC11A1,KDM4C,ZSCAN29,ADHFE1,FAM208A,WSCD1,TPCN2,ASXL3,VIPR2,UBE3B" MicroRNA "TCATCTC,MIR-143:MSigDB" "TCATCTC,MIR-143:MSigDB" MSigDB 5.46E-14 3.05E-10 1.07E-13 9.84E-13 28 134 "KCNH8,UNC5A,MARCH3,SRSF11,TAOK2,QKI,AKAP6,CSNK1G3,DTNB,PHF20L1,FGF1,UBE2E3,SYT3,RNF165,MYO6,CNOT4,NTRK2,STRN3,LRP12,SEPT4,MAPK7,SCAF8,PPM1E,LARP4,SEPT3,KLC2,PHTF2,NETO1" MicroRNA hsa-miR-5192:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-14 3.05E-10 1.07E-13 9.84E-13 28 134 "PDZD4,PPFIA4,CDC14B,BACH1,CSF1,CSNK1E,IP6K1,SPATA2,ZC3H11A,E2F6,VPS26C,FGFR1,BVES,ZFYVE27,GPR137C,PKD1,PKM,PLCD1,NKAIN1,HSD11B1L,NCBP3,MRAS,SHMT2,BTBD3,PKNOX2,IQSEC2,SLC38A1,ITM2C" MicroRNA hsa-miR-4692:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-14 3.10E-10 1.09E-13 9.99E-13 32 176 "ARHGDIA,DNAH17,ATP1B3,ISPD,EVI5L,CS,IGSF6,TMEM132C,PTK2B,FDFT1,SESN1,IRAK3,TNFAIP8L3,ZIC5,NBL1,TBC1D25,CDK18,RETREG2,QDPR,HSD11B1L,RMI1,SBF1,MYO18A,PEX26,TRIM67,NEK4,SLC37A2,FAM208A,TRPS1,TSN,RPL7L1,AMZ1" MicroRNA hsa-miR-4763-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.67E-14 3.17E-10 1.11E-13 1.02E-12 41 283 "ELFN2,RNF157,CPNE5,HCN2,LONRF2,PITPNM3,FAM131B,TM9SF4,IP6K1,HEYL,IRAK4,CELF1,CPLX1,AHDC1,GFER,FUT10,CACFD1,ZNF496,ZNF546,KCNK3,MAP4,PPM1L,TBC1D25,PDE3A,PKD1,POLR2F,NCR3LG1,TMEM145,SARS,MYH15,SOX11,SP2,LHPP,SSTR1,USP22,PUM2,NACC2,CBX5,DPYSL5,ITM2C,GAN" MicroRNA hsa-miR-539-5p:Functional MTI Functional MTI miRTarbase 5.68E-14 3.18E-10 1.11E-13 1.02E-12 35 210 "RNF157,SPOP,TNRC6C,SFMBT2,BACH1,CALM1,CLCN3,OSBPL3,SIPA1L1,PDE4DIP,RUBCN,DPYSL2,MSANTD4,HRASLS5,RNPS1,MSL1,IGF1,LAMA2,XRRA1,ADAM22,CNOT4,NUCB2,GPR137C,ZIK1,PTPRN2,SETD5,FAM161B,TRA2B,KIF21A,SOX11,ZEB1,ZMAT3,BCL2L13,MTCH1,DNALI1" MicroRNA hsa-miR-1227:PITA hsa-miR-1227:PITA_TOP PITA 5.97E-14 3.34E-10 1.17E-13 1.07E-12 23 88 "USP6,CDH2,QKI,ZNF521,ERC2,B3GAT3,SNAP91,NR1D2,PHC2,FRY,MCHR1,BACH2,NEGR1,IBA57,MBNL1,ZC3H12B,SETD5,DOCK9,CSMD1,TRPS1,EIF4ENIF1,UBE3A,ST8SIA2" MicroRNA hsa-miR-1193:TargetScan hsa-miR-1193 TargetScan 6.00E-14 3.36E-10 1.17E-13 1.08E-12 37 234 "ESYT2,LRFN1,CASK,ATP6V0A1,BCL7A,CACNA2D1,P2RX6,CBFA2T2,LRRFIP1,CRY2,MATR3,IP6K1,ELMSAN1,EGR3,RGS17,EZH1,GPD1,NXPH3,NEGR1,AGFG1,MSL1,IGF1,KCNB1,LSAMP,GPR155,MMP16,NOVA1,NOVA2,PRKACB,MYO18A,MBD5,MMS19,KLHL4,HIF3A,AP4E1,CBX5,HNRNPA3" MicroRNA hsa-miR-1197:PITA hsa-miR-1197:PITA_TOP PITA 6.43E-14 3.60E-10 1.26E-13 1.16E-12 33 188 "XKR4,UNC5A,DPY19L3,FOXN3,QKI,SOCS5,PRKAG2,AFF2,GABRG2,PPARGC1A,TNRC6A,GPD1,FRMD3,IBA57,MAT2A,MEIS2,NFIX,NTRK3,MAPK10,TMEM260,PTPRO,GTDC1,SLC25A36,CCDC88A,SP4,TEX2,CDK19,CLASP2,NKAIN2,PLCB1,KAT6B,EIF4ENIF1,SENP7" MicroRNA hsa-miR-933:mirSVR_highEffct hsa-miR-933:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.45E-14 3.61E-10 1.26E-13 1.16E-12 24 97 "PHYHD1,CFLAR,CAMK2G,MAGI1,PPT2,MAP4K4,LETMD1,ZNF521,CCDC144A,TCAF1,KIF19,RCAN2,SUCO,CELF1,GRIA2,IRAK3,MRAP2,IFT122,SP4,KDM4C,COBL,PPIL6,DCBLD1,FLRT2" MicroRNA hsa-miR-934:PITA hsa-miR-934:PITA_TOP PITA 6.45E-14 3.61E-10 1.26E-13 1.16E-12 24 97 "ALCAM,ATP2A2,RUNX1T1,DCLK1,MAGI1,SLC35F1,GPHN,ACSL4,FOXO3,AFF2,NEGR1,AGFG1,KCND2,NOVA1,LRRN3,KANSL1,OXR1,MSANTD2,RCOR3,TRIM2,ZBTB14,ZFAND5,EVI5,WNK3" MicroRNA "ATGAAGG,MIR-205:MSigDB" "ATGAAGG,MIR-205:MSigDB" MSigDB 6.46E-14 3.61E-10 1.26E-13 1.16E-12 29 145 "MAGI1,CHN1,B4GALT6,CLTC,QKI,CDC42BPB,CPEB2,PHC2,EPB41,ST6GALNAC3,LRRC37A6P,ACOT7,CLDN11,SEPT4,TMEM260,LRRK2,BTBD3,LIMS2,SP4,CDK19,SEPT3,PLCB1,MGRN1,DMXL2,SATB2,NACC2,TRPM2,TRPS1,ADAMTS9" MicroRNA "ACATATC,MIR-190:MSigDB" "ACATATC,MIR-190:MSigDB" MSigDB 6.78E-14 3.79E-10 1.32E-13 1.22E-12 19 57 "TBC1D14,SYNJ1,CLOCK,DMD,PHF20L1,GPHN,MEX3B,TNRC6A,HAS2,BACH2,MYO5A,PAX6,PCDH9,NLGN1,NFASC,TCF4,TRPS1,CELF4,NAV3" MicroRNA hsa-miR-1973:mirSVR_lowEffct hsa-miR-1973:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.37E-14 4.12E-10 1.44E-13 1.32E-12 39 260 "ABR,ACTN1,KLHL32,RNF157,AXIN2,ESYT2,ADGRF5,NCOA1,BMP7,ARHGEF2,ZNF521,MATR3,DBN1,CDON,DNM1L,ZNF589,PRKAG2,DISC1,KIF2A,ZFYVE27,MSR1,MYT1,PCSK5,PDPK1,PTPRG,ROBO2,PCMTD2,FNDC3A,RCOR3,DBNDD2,LMO3,SSTR2,CEP68,RPRM,PRTFDC1,PRDM8,URM1,PHTF2,FXR1" MicroRNA "ATAAGCT,MIR-21:MSigDB" "ATAAGCT,MIR-21:MSigDB" MSigDB 7.43E-14 4.16E-10 1.45E-13 1.33E-12 26 116 "CASKIN1,FUBP1,KRIT1,CNTFR,PHF14,ARHGAP24,RASGRP1,PLEKHA1,PAN3,SCML2,PCDH17,MATN2,MBNL1,PIK3R1,ING3,PPARA,PPP3CA,PBRM1,AP1AR,SATB1,CPEB3,FBXO11,BTBD3,ITPRID2,MPRIP,RNF103" MicroRNA hsa-miR-326:PITA hsa-miR-326:PITA_TOP PITA 7.52E-14 4.21E-10 1.46E-13 1.35E-12 33 189 "RALGAPA1,CASKIN1,ATP2B2,DLGAP2,WHRN,CRY2,CSNK1G3,RIMS4,FAM107B,DPYSL2,EBF1,EGR3,FGF11,GGT7,GNAO1,GPD2,ADAMTS6,MIER3,ZIC5,LRRTM1,NFIX,PALM,KCTD15,PRKAB2,PKIA,SEC14L1,FNDC3A,BTBD3,EPN2,ERBIN,TCF4,VLDLR,PPP1R3F" MicroRNA hsa-miR-330-5p:PITA hsa-miR-330-5p:PITA_TOP PITA 7.52E-14 4.21E-10 1.46E-13 1.35E-12 33 189 "RALGAPA1,CASKIN1,ATP2B2,DLGAP2,WHRN,CRY2,CSNK1G3,RIMS4,FAM107B,DPYSL2,EBF1,EGR3,FGF11,GGT7,GNAO1,GPD2,ADAMTS6,MIER3,ZIC5,LRRTM1,NFIX,PALM,KCTD15,PRKAB2,PKIA,SEC14L1,FNDC3A,BTBD3,EPN2,ERBIN,TCF4,VLDLR,PPP1R3F" MicroRNA hsa-miR-510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.60E-14 4.25E-10 1.48E-13 1.36E-12 31 167 "SLC24A4,MARCH3,COPB2,SRSF11,C2CD2,LIN54,SYNCRIP,GPR75,SHISAL1,IL6R,MAT2A,TM6SF1,PAX6,PSAT1,MINDY2,PPP2R5E,CEP97,SH3TC2,SETD5,FBXW7,CSRNP3,CPEB4,INAVA,FNBP1,MCF2L2,ATMIN,RUNDC3B,TRPS1,ZNF610,UBC,SPATA13" MicroRNA hsa-miR-4514:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.69E-14 4.31E-10 1.50E-13 1.38E-12 32 178 "ARHGDIA,DNAH17,ATP1B3,ISPD,EVI5L,CS,IGSF6,TMEM132C,PTK2B,FDFT1,SESN1,IRAK3,TNFAIP8L3,ZIC5,NBL1,TBC1D25,CDK18,RETREG2,QDPR,HSD11B1L,RMI1,SBF1,MYO18A,PEX26,TRIM67,NEK4,SLC37A2,FAM208A,TRPS1,TSN,RPL7L1,AMZ1" MicroRNA hsa-miR-5582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.70E-14 4.31E-10 1.50E-13 1.38E-12 38 248 "XKR4,TMCC3,PTCHD1,ZNF608,PHF12,CDC14B,ARNTL,ZBTB10,ATP2A2,ZNF583,ZNF555,CALM1,CLCN3,CLOCK,RIMS4,CHRDL1,STARD3NL,ZNF585B,SUCO,SYNCRIP,APOPT1,UFM1,GABRB3,RNPS1,GRIK4,FRMD5,SCIN,IL6R,PDE3A,GRAMD1C,DIRAS2,PTPRB,PTPRG,SETD5,TMLHE,ZNF106,ZIC2,EML6" MicroRNA hsa-miR-330-3p:Functional MTI Functional MTI miRTarbase 7.78E-14 4.35E-10 1.51E-13 1.39E-12 29 146 "RNF150,MTA3,BCAS1,SLIT2,CLTB,SPATA2,CASP8AP2,RASA4,CELF1,SYNPO,NEGR1,DHX35,TJAP1,METTL21A,MSI1,BLOC1S2,NTRK3,PFKFB3,PKM,ROBO1,FAM126B,SP4,NXT2,KIAA0930,SLC19A3,THRA,LRRC8A,RIMBP2,URM1" MicroRNA hsa-miR-3181:mirSVR_lowEffct hsa-miR-3181:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.22E-14 4.60E-10 1.60E-13 1.47E-12 43 312 "ADORA2A,ADRA1D,SPOP,PITPNM2,AMPD2,SEMA7A,CCAR2,ATP2A2,RGS11,RGS9,PPT2,ZNF521,SNCAIP,ELMSAN1,RASGRP2,TUBB3,GLI2,RAB30,IDH3A,L1CAM,CAMK2N2,NOVA2,PCBP3,SETD4,NLGN3,NLE1,PURG,POLR2F,NKAIN4,FAM66C,UBR7,STK32B,RCOR3,SP2,KDM4C,UNC5B,MTCL1,TPCN2,FLRT2,PLPPR2,P2RY12,MEIS3,FBXO36" MicroRNA hsa-miR-7158-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.57E-14 4.80E-10 1.67E-13 1.53E-12 30 157 "KIAA1211,PHF12,SEMA4G,ABCG2,TMEM184B,ANKRD44,PYGO1,GAPVD1,CRCP,COPS8,KCNN3,CREG2,PDE4D,TMOD2,PRKACB,PIGG,NCR3LG1,HSPA4L,SH3BP2,NUBPL,PEX26,ANKRD36,ERC1,SSTR2,STAC2,KLHL7,SLC19A3,ZNF708,ZFAND5,GAN" MicroRNA hsa-miR-1282:mirSVR_highEffct hsa-miR-1282:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.57E-14 4.80E-10 1.67E-13 1.53E-12 30 157 "INTS2,C1QTNF3,TNRC6C,ARHGEF7,CACNA1G,CA4,AKAP5,ARHGAP32,MAML1,COQ7,RCAN2,LRRC17,EYA1,FGF14,SMC2,NF1,JAKMIP1,PLIN1,RASGRF2,NEK11,PEAR1,CHD9,SLC2A5,SNRPN,KDM4C,UNC5B,ASTN2,HIF3A,ITGB3BP,TMPO" MicroRNA hsa-miR-619:PITA hsa-miR-619:PITA_TOP PITA 8.99E-14 5.03E-10 1.75E-13 1.61E-12 31 168 "RALGAPA1,ADCY6,OGT,RUNX1T1,CERS5,FOXN3,TMEM184B,CNR1,AHCTF1,FAM131B,CPEB2,PHC2,EGR3,EPB41,FGF13,EVL,SMAP1,RBPJ,MID1,SAMD5,MSI1,PCDH9,PDE1B,MAPK9,PTPRD,AMBRA1,CHD9,SOX11,TAL1,TMEM237,GAL3ST3" MicroRNA hsa-miR-487b:mirSVR_lowEffct hsa-miR-487b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.25E-14 5.18E-10 1.80E-13 1.65E-12 42 300 "KCNH8,KDM5D,AXIN2,LTBP4,CPNE5,PPP4R4,RNF182,DPY19L3,CACNA1G,CACNB4,CALB2,KYAT1,QKI,SRP14-AS1,ZNF521,DOCK4,HDAC4,FER,FGFR1,SEMA4D,WDR83,ZNF638,RNF165,FAM107A,ZNF667-AS1,BCAS3,PCMTD2,ATF7IP,SNCA,MBD5,SOX3,SYNE2,PCDHGA11,CYB561A3,AP4E1,SLC44A1,TNS1,PLEKHH2,FSTL5,PRDM8,PHTF2,FBXO36" MicroRNA hsa-miR-2681-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.36E-14 5.24E-10 1.82E-13 1.67E-12 29 147 "HFM1,IGDCC3,GPRASP1,DCAF8,YTHDC1,EBF1,ASB3,RAB9B,FDFT1,JKAMP,HHIPL1,PRRC2B,ZHX1,RBPJ,IBA57,KCNN3,ENOX1,RXRA,CNKSR2,MPRIP,ARHGAP9,SLC44A1,SGK3,VLDLR,CELF4,DHX33,KAT6A,JMJD1C,FXR1" MicroRNA hsa-miR-486-3p:Functional MTI Functional MTI miRTarbase 9.61E-14 5.37E-10 1.86E-13 1.72E-12 34 202 "NDRG3,ELFN2,CASKIN1,TXNDC16,AMH,OGT,PHF12,BCL7A,HCN2,CAMK2A,CACNA2D2,PLXNA4,MYADM,IP6K1,SPATA2,MRNIP,ERBB2,AHDC1,GFER,CRCP,POLL,ELOVL5,MAP4,HS6ST3,PKD1,POLR2F,RXRA,SARS,COPZ1,TMCC1,NSD1,NACC2,TUBB2A,CIAPIN1" MicroRNA hsa-miR-637:PITA hsa-miR-637:PITA_TOP PITA 9.81E-14 5.49E-10 1.90E-13 1.75E-12 28 137 "PITPNM2,NCOA1,CACNA1A,CABP7,CACNA2D2,NRXN3,CNTFR,CLIP3,PPP1R16B,RUSC2,SLC12A6,DUSP9,PHC2,AGAP3,USP21,CPLX2,PPARGC1A,PLPP7,ATXN2L,MAPT,NFIX,SBF1,FUZ,CPEB4,STAC2,NSD1,RELL2,SMARCAD1" MicroRNA hsa-miR-891a:mirSVR_highEffct hsa-miR-891a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.81E-14 5.49E-10 1.90E-13 1.75E-12 28 137 "NCKAP5,XKR4,TAOK1,ADGRF5,CHID1,RGS9,AP1M1,MTMR7,DAPK1,HS3ST2,MBNL2,FGFR1,SLC37A3,NOP56,ST6GALNAC3,OGA,KIAA1958,SOX21,NPTX2,TMEM260,EXD2,CARF,DHX30,DIP2A,TMPO,FAM155A,PLEKHH2,ADAMTS9" MicroRNA hsa-miR-501-5p:Functional MTI Functional MTI miRTarbase 1.02E-13 5.72E-10 1.98E-13 1.82E-12 30 158 "MTUS1,TAOK1,TRMT9B,ASGR1,SCARB1,LONRF2,HINFP,RGS6,PPP1R16B,C2CD2L,FSD1L,ZNF585B,GORAB,ST6GALNAC3,HHIPL1,MTHFD2,PRRC2B,RNF165,HAS2,NKD1,KCNN3,PLIN1,ZMAT4,PGBD4,SLC8A1,ELOVL4,TACC1,SIK3,NR2C2,NELFE" MicroRNA hsa-miR-191*:mirSVR_highEffct hsa-miR-191*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-13 5.75E-10 1.99E-13 1.83E-12 37 238 "DST,ARHGEF7,KALRN,SMARCAL1,DZIP3,DCAF4,GAPVD1,MAML1,GSDME,CHRDL1,PHF20L1,SRRM1,FER,GPD2,RNF165,KIF5A,MYT1,DNHD1,SLC11A2,OGG1,ZFHX4,MEG3,PPP4R3A,RCOR3,LIMCH1,FNBP1,KLHL7,SYN2,CAMTA1,ZEB1,TSN,TOM1L2,RICTOR,UPF3A,PCBP4,HNRNPA3,PHTF2" MicroRNA "ATTACAT,MIR-380-3P:MSigDB" "ATTACAT,MIR-380-3P:MSigDB" MSigDB 1.05E-13 5.88E-10 2.04E-13 1.87E-12 24 99 "PCDH19,APAF1,EIF4G2,FGF12,C15orf41,TPPP,ATXN2L,MBNL1,MEF2C,KITLG,CNOT4,PRKCB,FIGN,FNDC3A,CPEB4,SNAP25,SP4,ZNF423,LARP4,KLHL4,ZFPM2,TRPS1,FLRT2,PHTF2" MicroRNA hsa-miR-658:mirSVR_highEffct hsa-miR-658:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-13 6.23E-10 2.16E-13 1.98E-12 34 203 "ZNF578,SUGT1P4-STRA6LP-CCDC180,MARCH3,TPP1,CNTFR,TMEM132C,ATP6V1H,PLCD4,RNF165,AGBL5,MSL1,TJAP1,LINC00634,NF1,RETREG1,APTX,DPF2,RPS20,CCDC92,CLASP2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TRIO,DCBLD1,PRR18,PPP1R3F,UBE3B,CASC15" MicroRNA hsa-miR-9500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-13 6.23E-10 2.16E-13 1.98E-12 34 203 "ELFN2,OGT,ARHGDIA,ARRB2,TTLL9,BCL7A,LDHD,HAP1,USP2,TM9SF4,HSPA12B,GTF2IRD2,CAMKK2,GFER,CRCP,GSN,NXPH3,SHISA6,SOWAHA,NKD1,NFIX,NPTX2,CLDN11,KCTD15,NLE1,NCR3LG1,PRRT2,SLC25A36,PEX26,NACC2,WBP2,TUBB2A,INTS3,URM1" MicroRNA hsa-miR-382-5p:TargetScan hsa-miR-382-5p TargetScan 1.12E-13 6.29E-10 2.17E-13 2.00E-12 29 148 "GALNT13,CASKIN1,CDK13,BACH1,P2RX6,CLTC,HIPK3,PLXNC1,AMOTL2,GABRB3,HNMT,NEGR1,METTL21A,KCNQ3,LSAMP,GPR155,MBNL1,MMP16,SAMD5,PDPK1,LRP12,RASGRF1,RPE,CPEB3,BTBD3,BTBD7,DICER1,NAV3,GAN" MicroRNA hsa-miR-196a-5p:Functional MTI Functional MTI miRTarbase 1.30E-13 7.30E-10 2.52E-13 2.32E-12 42 303 "BRAP,MTUS1,FAM135A,IGDCC4,ATP1A1,BACH1,BCS1L,NRP2,RAB29,CALM1,SPATA2,ZBTB24,MED12,DCTN4,KATNAL1,REEP2,TUBA1B,FKTN,SARAF,USP19,MSL3,GLUL,PRUNE2,GRIK4,SLC35G1,KPNA5,IPO5,MAP4,MPP2,MTRF1L,RDX,ARMH4,SBF1,KIF27,TRA2B,HSPA4L,SH3GL3,CPEB3,SLC6A8,MYCBP2,KLHL7,SMARCAD1" MicroRNA hsa-miR-373-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-13 7.90E-10 2.73E-13 2.51E-12 47 371 "TMEM132B,SLC24A4,TXNDC16,ZBED1,ZNF445,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,MTX3,FEM1B,PLEKHA1,C8orf37,COQ7,SRCAP,RNPS1,TNRC6A,FUT10,DDX19B,CHST6,MITF,DBNL,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,FNBP1,SP4,ADAMTS17,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,TBC1D15,ZNF24" MicroRNA hsa-miR-632:PITA hsa-miR-632:PITA_TOP PITA 1.44E-13 8.04E-10 2.78E-13 2.56E-12 28 139 "PTCHD1,FAM131A,TPP1,QKI,MAP4K4,RIMS2,SNPH,GABRB3,PPARGC1A,GNAO1,KCND2,MBNL1,MYO5A,NPTX1,NLGN3,ANKRD16,SNRK,RDX,SLC25A36,SLC6A8,CPEB4,SP4,PEG10,NKAIN2,FBXW11,OSBP2,ZIC1,PCBP4" MicroRNA hsa-miR-518d-3p:mirSVR_highEffct hsa-miR-518d-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-13 8.16E-10 2.82E-13 2.60E-12 32 182 "LRFN2,ZNF608,CASK,ARHGEF7,CFAP410,SMARCAL1,SOCS5,DTNA,EDN3,ACSL4,GORAB,FHL1,SYT17,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,ZC3H12B,ZNF827,EXOSC10,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,NSD1,TSN,PLEKHH2,KCNK12,PARP11" MicroRNA hsa-miR-548ah-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-13 8.18E-10 2.82E-13 2.60E-12 41 291 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548am-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-13 8.18E-10 2.82E-13 2.60E-12 41 291 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-383-5p.1:TargetScan hsa-miR-383-5p.1 TargetScan 1.48E-13 8.28E-10 2.86E-13 2.63E-12 31 171 "KCTD16,C1orf52,QKI,HDAC9,DNAL1,CALCRL,PAN3,ERBB4,FECH,RAPGEF6,PCDH17,AGFG1,KCNB1,HS6ST3,NNAT,CNOT4,PAX6,PTPRE,GTDC1,FIGN,GSTCD,RORB,GLDN,EPN2,CDK19,MPRIP,FRYL,HIF3A,ITGB3BP,PPIL6,EPM2A" MicroRNA hsa-miR-196a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-13 8.35E-10 2.88E-13 2.65E-12 34 205 "XKR4,SLC24A4,HACE1,ARSE,ATP1B3,MTMR3,SUSD5,UBXN2A,GAPVD1,CENPL,MTX3,EIF4G2,EPB41,ZNF549,ZNF234,CRCP,GPR75,LINGO1,DDX19B,SLC11A2,TATDN3,PEX2,ZNF844,KLHL11,KLHDC8A,SEC31A,KANSL3,SLC11A1,IQSEC2,ADAMTS17,RPL7L1,TBC1D15,TRIM16L,TIGD6" MicroRNA hsa-miR-3124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-13 8.35E-10 2.88E-13 2.65E-12 34 205 "FMNL2,KCTD16,SPOP,CDC42BPA,GAS7,PRX,ATP1A1,RUNX1T1,ZBED1,LRRFIP1,EPHB1,SLC43A2,CEP85L,MRVI1,CEP78,UFM1,PPARGC1A,HMGCR,LSAMP,MBNL1,MYO5A,GLIPR1L2,ZNF426,PIGG,SPIN3,TCP11L1,ATXN7,SCN2B,SP4,SLC19A3,RUNDC3B,RICTOR,ZNF138,FRMD6" MicroRNA hsa-miR-873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-13 8.72E-10 3.01E-13 2.77E-12 39 266 "ABCF1,SLC24A4,SORCS2,ZBTB10,WASF1,DDR1,PPP1R16B,IST1,SNX29,POLR1B,HHIPL1,GPR75,RABL2A,PACSIN2,SHISA6,ITPKB,KCNH2,KIF5A,LAMP2,MEIS1,TBC1D25,ABCB1,PKM,SMIM7,MTRF1L,PPP2R5E,ALG9,SGK1,SH3BP2,SLC2A5,SP2,ZNF423,ZSCAN29,KANK1,MGRN1,ARL10,NACC2,RGMB,GDPD5" MicroRNA hsa-miR-371b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-13 8.73E-10 3.01E-13 2.77E-12 47 372 "TMEM132B,SLC24A4,TXNDC16,ZBED1,ZNF445,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,MTX3,FEM1B,PLEKHA1,C8orf37,COQ7,SRCAP,RNPS1,TNRC6A,FUT10,DDX19B,CHST6,MITF,DBNL,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,FNBP1,SP4,ADAMTS17,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,TBC1D15,ZNF24" MicroRNA hsa-miR-581:PITA hsa-miR-581:PITA_TOP PITA 1.61E-13 9.02E-10 3.11E-13 2.86E-12 29 150 "DPP10,MAP4K3,STX16,LDLRAD4,CACNA1A,DLGAP2,NRXN3,ARHGEF6,AKAP6,USP6NL,TENM1,RCAN2,FOXO3,GABRB3,PCDH17,STON1,AGFG1,KITLG,NFIX,PCDH9,DIRAS2,PTPRD,SUPT20H,FBXO11,SOX11,SP4,PEG10,CDK19,FLRT2" MicroRNA "GAGCTGG,MIR-337:MSigDB" "GAGCTGG,MIR-337:MSigDB" MSigDB 1.61E-13 9.02E-10 3.11E-13 2.86E-12 29 150 "ABCF1,KCNH8,SEMA6A,GPRASP2,CHRD,CAMK2G,USP6,DGKI,SEC24C,FAM131B,B3GAT3,USP19,GLYR1,GPD1,RNF165,PACSIN2,ATXN2L,ACOT7,LRRC75A,KCND1,MAT2A,GIT1,ZNF827,UBR7,IQSEC2,NFASC,POGZ,THRA,PPP1R3F" MicroRNA hsa-miR-548j-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-13 9.19E-10 3.16E-13 2.91E-12 41 292 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-4789-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-13 9.31E-10 3.20E-13 2.95E-12 38 254 "MTA3,ST3GAL5,C1orf52,TBRG4,COPB2,B4GALT6,TBPL1,ANKRD44,MYADM,DGKG,DBT,PITPNC1,SV2B,CPEB2,CERCAM,ZBED3,MPP6,GABRG1,GCK,MMADHC,COPS8,SCIN,IL6ST,KLHL23,NCOA7,NEXMIF,PIK3R1,KANSL1,SNRK,CSRNP3,SLC12A2,FAM126B,DIP2A,GPRIN3,SIK3,BEX4,CSMD1,NR2C2" MicroRNA hsa-miR-571:PITA hsa-miR-571:PITA_TOP PITA 1.68E-13 9.39E-10 3.23E-13 2.97E-12 23 92 "APLP1,CALM1,DBN1,ERBB4,DOT1L,KTN1,MAP2,MAT2A,NLGN3,LAMA1,OXR1,GTDC1,ZFHX4,ROBO2,KCNIP1,HECW1,LARP4,FAM208A,TCF4,RPGRIP1L,SLC44A1,DPYSL5,ST7" MicroRNA hsa-miR-500b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-13 9.66E-10 3.32E-13 3.06E-12 34 206 "ARMC12,BARD1,ZBED1,RTTN,PYGO1,DBT,OPTN,C3orf18,FGF1,MSANTD4,GPR75,KAT7,SLC2A6,DDX19B,ZNF491,NOVA2,TMOD2,ZDHHC8,KCTD15,GPSM2,STRN3,PIGG,PTCH1,MTMR10,PGBD4,HSPA4L,ERC1,KLHL7,KIAA0930,ZNF34,WRN,ZNF74,TIGD6,AP3B2" MicroRNA hsa-miR-3186-3p:mirSVR_lowEffct hsa-miR-3186-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-13 9.75E-10 3.35E-13 3.09E-12 31 172 "FZD9,AP2A2,AMPH,RGS20,ASIC3,FAM149A,IGDCC3,PITPNC1,ZNF582-AS1,SLC29A4,DNM1L,SPEG,BAIAP2,FHL1,TPK1,ADAMTS13,ZBTB49,CPT1C,GIT1,NNAT,WBP1L,IQSEC3,MAST1,CAMTA2,SSPO,PJA1,VWCE,DICER1-AS1,C9orf85,CIAPIN1,DOCK8" MicroRNA "CAGCCTC,MIR-485-5P:MSigDB" "CAGCCTC,MIR-485-5P:MSigDB" MSigDB 1.78E-13 9.98E-10 3.43E-13 3.16E-12 27 130 "SYN3,SEMA4G,CCAR2,TAOK2,NGEF,QKI,CNTFR,ARHGAP32,NBEA,GABRB3,PPARGC1A,TTBK1,RNF165,TTYH2,CAMK2N2,NOVA1,CDK18,PLEC,POU6F1,CHD9,ELMO2,ANKFN1,TMCC1,SPTB,HPS4,WNK3,NELFE" MicroRNA hsa-miR-548ae-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-13 1.03E-09 3.54E-13 3.26E-12 41 293 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548x-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-13 1.03E-09 3.54E-13 3.26E-12 41 293 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548aj-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-13 1.03E-09 3.54E-13 3.26E-12 41 293 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548aq-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-13 1.03E-09 3.54E-13 3.26E-12 41 293 "TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,GRIK4,FRMD5,IL6R,MEF2C,MYO6,PSAT1,PPP2R5E,KANSL1,PKIA,PTPRB,PTPRG,TMLHE,EXD2,BTBD3,ATF7IP,FAM126B,ALG1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-518a-3p:mirSVR_highEffct hsa-miR-518a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-13 1.05E-09 3.61E-13 3.32E-12 33 195 "LRFN2,ZNF608,CASK,ARHGEF7,CFAP410,SMARCAL1,SOCS5,DTNA,EDN3,ACSL4,FGFR1,FHL1,SYT17,CCDC184,ZHX1,LAMP2,KITLG,ZC3H12B,ZNF827,EXOSC10,RBBP8,ZDHHC14,ZFHX4,FBXO11,FNDC3A,PLCB1,MCF2L,TBCEL,NSD1,TSN,PLEKHH2,KCNK12,PARP11" MicroRNA hsa-miR-3927-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-13 1.12E-09 3.83E-13 3.52E-12 32 184 "MTUS1,ZNF578,FAM135A,AQP6,DYNLL1,CRY2,MTX3,DNAH9,MAMLD1,E2F6,EDN1,EIF4G2,MRNIP,DISC1,GATM,POLL,RABL2A,SLC35G1,KPNA5,SLC11A2,QDPR,FIGN,ARMH4,CSRNP3,HSPA4L,MAPKBP1,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1,FXR1" MicroRNA hsa-miR-219a-2-3p:TargetScan hsa-miR-219a-2-3p TargetScan 2.09E-13 1.17E-09 4.01E-13 3.69E-12 28 141 "HACE1,PDE8B,DST,LDB2,DGKI,LETMD1,ARHGEF10,ERBB4,ANKFY1,PSD2,RAPGEF6,IQGAP2,GLYR1,MIER3,IGF1,MEF2C,MXI1,MYO5A,NOVA2,GPR173,KHDRBS2,KLHL11,SATB1,FAM208A,RPGRIP1L,DOK6,KCNK12,GAN" MicroRNA hsa-miR-616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-13 1.17E-09 4.02E-13 3.70E-12 47 375 "TMEM132B,SLC24A4,TXNDC16,ZBED1,ZNF445,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,MTX3,FEM1B,PLEKHA1,C8orf37,COQ7,SRCAP,RNPS1,TNRC6A,FUT10,DDX19B,CHST6,MITF,DBNL,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,FNBP1,SP4,ADAMTS17,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,TBC1D15,ZNF24" MicroRNA hsa-miR-4671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-13 1.20E-09 4.09E-13 3.77E-12 24 102 "ADD1,ABCD2,PHF12,CLCN3,TPP1,DAPK1,DLC1,SEC23B,FLT1,MSANTD4,MALT1,PRUNE2,ZIC5,ZNF678,PURG,PTPRG,CLIP1,CDK19,SPART,TROVE2,ZMAT3,THRA,ZNF24,ZNF154" MicroRNA hsa-miR-6809-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-13 1.20E-09 4.09E-13 3.77E-12 24 102 "PHF12,CCNT1,PUM1,LIN54,E2F6,PHC2,CRCP,PRRC2B,LILRA2,RBPJ,ZNF678,PPM1L,GPR137C,PSD,ZIK1,SETD5,MCMBP,CLASP1,NSD1,SLC44A1,RPL7L1,UBTF,CLDND1,DPYSL5" MicroRNA hsa-miR-154-3p:TargetScan hsa-miR-154-3p TargetScan 2.14E-13 1.20E-09 4.10E-13 3.77E-12 26 121 "ASIC1,HECW2,ARHGAP20,APC,MARCH3,MTMR3,RUNX1T1,FOXN3,ABCG2,CNR1,DOCK4,RASGRP1,FAM13A,PPARGC1A,GPR155,MEIS1,PDE4D,MTMR10,HUNK,AP1AR,MBD5,PDZD2,ARHGAP26,PUM2,ANKS1B,EVI5" MicroRNA "GGCACTT,MIR-519E:MSigDB" "GGCACTT,MIR-519E:MSigDB" MSigDB 2.14E-13 1.20E-09 4.10E-13 3.77E-12 26 121 "CDK10,SEMA4G,MARK4,QKI,PCYT1B,ZNF385A,CLOCK,SPATA2,SCML2,NBEA,OGA,XRN1,RETREG2,PTPRD,PTPRG,ZFHX4,FAM102A,BTBD7,SOX11,ITPRID2,TBL1X,SYNE1,DPYSL5,KAT6A,ST8SIA2,GAN" MicroRNA hsa-miR-487a-3p:TargetScan hsa-miR-487a-3p TargetScan 2.14E-13 1.20E-09 4.10E-13 3.77E-12 26 121 "ASIC1,HECW2,ARHGAP20,APC,MARCH3,MTMR3,RUNX1T1,FOXN3,ABCG2,CNR1,DOCK4,RASGRP1,FAM13A,PPARGC1A,GPR155,MEIS1,PDE4D,MTMR10,HUNK,AP1AR,MBD5,PDZD2,ARHGAP26,PUM2,ANKS1B,EVI5" MicroRNA hsa-miR-675:mirSVR_highEffct hsa-miR-675:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.15E-13 1.21E-09 4.12E-13 3.79E-12 23 93 "ADGRB2,SYNJ2,CASTOR3,L3MBTL4,NOG,SUMF2,EPHB1,SRRM1,ZNF274,KCNN1,NNAT,WDR25,NKAIN1,ATAT1,NCBP3,DGLUCY,SCN8A,KDM4C,ELP5,TRIO,RNF103,SEMA3B,CASC15" MicroRNA hsa-miR-625:PITA hsa-miR-625:PITA_TOP PITA 2.17E-13 1.21E-09 4.15E-13 3.82E-12 27 131 "HECW2,PCDH19,FUBP1,JAZF1,CACNA2D2,CLTC,ZNF385A,CLIP3,SLC12A6,DUSP9,KMT5B,ATXN2L,IGF1,SCAMP5,NFIX,PPP2R2C,TMEM260,UBR7,SETD5,FBXW7,CPEB4,SMARCC2,ANKFN1,MTCL1,TRIM2,TRPS1,CELF4" MicroRNA hsa-miR-1248:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-13 1.35E-09 4.59E-13 4.23E-12 30 163 "RALGAPA1,XKR4,FMNL2,RNF157,ADD1,SPOP,SFMBT2,B4GALT6,PLCXD3,TM9SF4,SCRN1,IP6K1,CPEB2,OPTN,MRO,EMX2,EPHB1,ST3GAL6,ZMAT1,NEGR1,NPTX2,PDE1B,RASGEF1B,PRKCB,KCNIP3,BTBD7,EXOC7,SZT2,TNS1,RNF146" MicroRNA hsa-miR-512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-13 1.43E-09 4.88E-13 4.49E-12 42 309 "RNF157,OSBPL8,ZNF578,TAOK1,ATP1B3,LDHD,PRC1,ZBED1,DIS3L,SOCS5,UBXN2A,DNAL1,SLC12A6,FEM1B,IRAK4,TLR7,GTF2IRD2,SEC23B,TRAF3IP2,KIAA1841,SRCAP,MALT1,CRCP,HAS2,ZNF491,IL6ST,KCNB1,GPR155,ZNF426,LRP12,C12orf49,SBF1,HSPA4L,SLC8A1,SP2,STAC2,GPRIN3,ZMAT3,CBX5,PARD3,CADM2,MPPE1" MicroRNA "AGGCACT,MIR-515-3P:MSigDB" "AGGCACT,MIR-515-3P:MSigDB" MSigDB 2.60E-13 1.45E-09 4.96E-13 4.57E-12 22 85 "OGT,QKI,CLOCK,CS,DCTN4,EPB41,LRRC37A6P,PCDH17,XRN1,PTPRG,RIPOR1,CYB561D1,SEMA6D,BTBD3,SOX11,ITPRID2,SYT1,SYNE1,TRIM9,DPYSL5,KAT6A,GAN" MicroRNA hsa-miR-1298-5p:TargetScan hsa-miR-1298-5p TargetScan 2.63E-13 1.47E-09 5.02E-13 4.62E-12 26 122 "C3orf14,BEND6,OSBPL6,APC,ATP2B2,BMP7,CACNA1I,CFL2,IGDCC3,CNTNAP2,FAM131B,CYBB,RAB39B,GABRB3,AGFG1,CHIC1,MITF,PDE4D,GNG2,PPP2R2C,CNNM2,RXRA,ANKRD12,NR2C2,RGS7BP,FXR1" MicroRNA hsa-miR-920:PITA hsa-miR-920:PITA_TOP PITA 2.69E-13 1.50E-09 5.13E-13 4.73E-12 24 103 "ASIC1,SEMA4G,ADGRB1,CACNA1A,CALB2,TAOK2,RHOBTB1,ELN,SRRM1,AGAP3,TTBK1,GRIN2D,KAT7,BACH2,CNOT4,NLGN3,ANKRD16,SH3TC2,MYO18A,TET1,GKAP1,SP2,THRA,KAT6A" MicroRNA hsa-miR-6831-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.72E-13 1.52E-09 5.18E-13 4.77E-12 32 186 "MTUS1,ZNF578,FAM135A,AQP6,DYNLL1,CRY2,MTX3,DNAH9,MAMLD1,E2F6,EDN1,EIF4G2,MRNIP,DISC1,GATM,POLL,RABL2A,SLC35G1,KPNA5,SLC11A2,QDPR,FIGN,ARMH4,CSRNP3,HSPA4L,MAPKBP1,NSD1,CBX5,TUBB2A,ZNF28,SMARCAD1,FXR1" MicroRNA hsa-miR-663b:mirSVR_highEffct hsa-miR-663b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-13 1.63E-09 5.56E-13 5.11E-12 40 284 "GALNT13,ADD2,OSBPL6,AMPD2,MYH7B,SLC2A11,RGS9,DST,CACNA1G,CERS5,EPS15L1,MAP4K4,COL9A1,SLC4A8,IP6K1,EDNRB,FCF1,MRPL10,NRN1,ACSL4,ADAM28,FREM1,BRD8,GRIA2,GSN,NCKAP1L,RBPJ,KNDC1,MN1,GIT1,KLK6,RPL15,FAM214B,SEPHS1,PEG10,ZSCAN29,TACR1,FAM208A,ZNF23,FIP1L1" MicroRNA hsa-miR-1287:PITA hsa-miR-1287:PITA_TOP PITA 3.05E-13 1.71E-09 5.82E-13 5.36E-12 25 113 "XKR4,CA8,CACNB4,ZMYM4,CHN1,QKI,ZNF385A,PREPL,LYPD1,MBNL2,SPEG,GABRB3,PSIP1,KIAA1755,CNOT4,PMP22,MAPK10,RIC8B,FBXO11,SLC8A1,SOX11,ERC1,ZFAND5,NAV3,KAT6A" MicroRNA hsa-miR-6867-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-13 1.71E-09 5.82E-13 5.36E-12 34 210 "ASPA,ZNF582,BACH1,CBS,CCNT1,QKI,PITPNM3,CYBB,SPATA2,PHF20L1,EMX2,RAPGEF6,SRRM4,ZNF638,KIAA1958,PADI2,SHISA6,KCNQ3,STMN1,LSAMP,MBNL1,GNG2,SDK2,MTMR10,PTPRG,ZFP1,ZNF415,DIP2A,RUNDC3B,SSBP2,TSPAN11,ZNF781,ZNF138,URM1" MicroRNA hsa-miR-6836-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-13 1.71E-09 5.82E-13 5.36E-12 34 210 "MTA3,GYG2,CACNA1A,IGLON5,RTTN,KIAA0408,TMEM170A,KIAA0319,KRBA2,CNNM1,RGS17,FLYWCH1,PDLIM5,MSANTD4,RAB40B,NXPH3,DDX19B,NKD1,LIMS1,GPR155,FITM2,PIGG,STX1B,GALNT10,PEX26,FAIM2,TROVE2,AGTPBP1,PCDHA6,ARL10,ERCC6L2,FAM124A,PARD3,AGMO" MicroRNA hsa-miR-5580-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-13 1.71E-09 5.82E-13 5.36E-12 34 210 "ABCF1,FMNL2,TBRG4,CFL2,DAPK1,YAF2,CERCAM,RCAN2,TRMO,ZBED3,FYN,GABRG1,GCK,MMADHC,KCNB1,KLHL23,L1CAM,NEXMIF,NLGN3,PIK3R1,PTPRB,SH3TC2,GTDC1,ZNF532,CSRNP3,ZFP30,CNKSR2,SEPHS1,SLC12A2,FAM126B,BEX4,KCNK12,MFF,EVI5" MicroRNA hsa-miR-744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-13 1.72E-09 5.86E-13 5.40E-12 51 436 "AP2A2,GPRASP2,PRX,ARHGDIA,MARCH3,ZSCAN18,CACNA1A,ARHGEF2,CDC25B,MATR3,IP6K1,SEC16A,NR1D2,FARSB,PHC2,EIF4G1,MTSS1L,TUBA1B,RACK1,FGFR1,HPCAL4,FOXO3,TMEM175,USP21,DISC1,SRCAP,GFER,TDRKH,DIDO1,ATXN2L,NKD1,TJAP1,STMN1,LIMS1,NFIX,PDE4A,PDPK1,MAPK7,PTGR2,SALL1,SBF1,WDR37,ATF7IP,SYPL1,MGRN1,ATMIN,TIAM1,WBP2,TSC2,INTS3,TUBA1A" MicroRNA hsa-miR-8072:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-13 1.72E-09 5.86E-13 5.40E-12 18 54 "PDZD4,PRX,DNAH17,CACNA1B,CBARP,ELMSAN1,MTSS1L,CPLX1,MSI1,FXYD1,NMNAT2,PEG10,ARC,WSCD1,CLASP1,VGF,CLIP2,CELF4" MicroRNA hsa-miR-3960:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-13 1.72E-09 5.86E-13 5.40E-12 18 54 "PDZD4,PRX,DNAH17,CACNA1B,CBARP,ELMSAN1,MTSS1L,CPLX1,MSI1,FXYD1,NMNAT2,PEG10,ARC,WSCD1,CLASP1,VGF,CLIP2,CELF4" MicroRNA hsa-miR-766:PITA hsa-miR-766:PITA_TOP PITA 3.26E-13 1.82E-09 6.20E-13 5.71E-12 29 154 "ASIC1,TMEM132B,TAOK1,LRFN1,HAP1,CDH2,OSBPL3,RIMS4,B3GAT3,PAN3,SESN1,TNRC6A,GRIA2,MAP4K5,IGF1,IBA57,INSM1,KCND1,ZNF827,MINDY2,MORC4,FAM219A,SOX11,LARP4,SYNE2,PLCB1,TCF4,CADM2,PPP1R3F" MicroRNA hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 3.35E-13 1.88E-09 6.37E-13 5.87E-12 30 165 "ARNTL,RUNX1T1,NUMBL,AHCTF1,CLOCK,CSF1,CSNK1G3,RIMS4,ERC2,IST1,CHRDL1,ERGIC3,GABRB3,GFRA2,PCDH17,RNPS1,BACH2,MAP2,MSI1,GTDC1,PBRM1,PEX26,MBD5,DIP2A,COBL,NR2C2,BCL2L13,CLIP2,GAL3ST3,HNRNPA3" MicroRNA "ATGCAGT,MIR-217:MSigDB" "ATGCAGT,MIR-217:MSigDB" MSigDB 3.38E-13 1.89E-09 6.41E-13 5.91E-12 24 104 "OGT,VAT1L,ADGRB3,CAPN3,DLGAP2,CHN2,MYEF2,YAF2,LRRC37A6P,PCDH17,NOVA1,SEPT4,POLG,ARMH4,FBXO11,SOX11,ELOVL4,STX1A,TACC1,FBXW11,SIRT1,TBC1D15,RICTOR,SENP7" MicroRNA hsa-miR-29c*:mirSVR_highEffct hsa-miR-29c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.38E-13 1.89E-09 6.41E-13 5.91E-12 24 104 "CHN2,ABCG2,C8orf37,ENPP6,ADGRV1,GPD2,RABL2A,MEIS1,MYCN,ZNF862,CDK18,PPP2R5E,BDNF-AS,TMEM255A,ATP8B4,CNKSR2,CCDC92,USP33,KANK1,SYNE1,MTMR14,INTS3,URM1,FIP1L1" MicroRNA hsa-miR-222-3p:Functional MTI Functional MTI miRTarbase 3.38E-13 1.89E-09 6.43E-13 5.92E-12 48 394 "FUBP1,CAST,NFS1,ABCG2,QKI,MROH8,SEC24C,ZFYVE16,DBN1,POM121,TOM1,PLXNC1,EPB41L2,FOXO3,SMC2,TCERG1,RNPS1,GRB10,FICD,KIT,IPO5,STMN1,MAT2A,KITLG,DBNL,CDK18,OLA1,PKM,NLE1,EXOSC10,UBR7,SLC25A36,YY1AP1,CASC3,ZFP30,ZFP1,SMARCA4,TMCC1,FAM126B,SS18,SLC19A3,DICER1,TP53BP2,TRPS1,ZNF708,ZFAND5,STOX2,CIAPIN1" MicroRNA hsa-miR-877-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-13 1.94E-09 6.57E-13 6.05E-12 36 235 "ARHGDIA,MTMR3,USP2,LRRFIP1,TPP1,STOML1,FBXO7,TMEM184B,ARHGEF6,LETMD1,SEC24C,INTS1,SEC16A,VPS26C,HSPA12B,TUBA1B,RACK1,AMOTL2,AFF2,CELF1,CRCP,GLUL,GRB10,AFF1,NACA,CHAMP1,CASC3,TET1,USP33,STAU1,THRA,MTMR14,UBC,UCHL1,ZBTB38,NELFE" MicroRNA hsa-miR-1237-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-13 2.02E-09 6.86E-13 6.32E-12 28 144 "RALGAPA1,XKR4,FMNL2,GALNT13,RNF157,ADD1,SPOP,SFMBT2,B4GALT6,PLCXD3,TM9SF4,CPEB2,OPTN,EMX2,EPHB1,ST3GAL6,ZMAT1,NEGR1,IBA57,KCNN3,PDE3A,RASGEF1B,KCNIP3,ZNF430,EXOC7,SZT2,ZNF106,TNS1" MicroRNA hsa-miR-4796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.67E-13 2.05E-09 6.96E-13 6.41E-12 40 286 "FMNL2,PLEKHH1,FZD9,SEMA7A,EPS15L1,CPS1,UBXN2A,FBXL5,KMT5B,EIF5,CERCAM,HHIPL1,SYT17,C15orf41,SESN1,TNRC6A,CBX1,LUZP2,PRUNE2,FUT10,SOWAHA,METTL21A,KCNB1,KCNN1,MAPT,ZFYVE21,LRP12,PRKCB,CEP97,RAP1GDS1,TMEM200C,TRIM67,FAM126B,SP4,NACC2,RGMB,TUBB2A,EMSY,WNK3,NETO2" MicroRNA hsa-miR-23b-5p:Functional MTI Functional MTI miRTarbase 3.87E-13 2.16E-09 7.34E-13 6.75E-12 29 155 "AS3MT,SLC4A4,DDR1,ZNF385A,CSNK1E,ZBTB24,RGS17,TUBD1,FOXO3,SLC35G1,CAMK2N2,LIMS1,PPM1L,SAMD5,FITM2,PRODH,APTX,ZSCAN2,GTDC1,ALG9,PGBD4,HSD11B1L,AMBRA1,WDR37,PEX26,SP2,AGTPBP1,ARL10,SSBP2" MicroRNA hsa-miR-23a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-13 2.16E-09 7.34E-13 6.75E-12 29 155 "AS3MT,APAF1,SLC4A4,DDR1,ZNF385A,CSNK1E,ZBTB24,RGS17,TUBD1,FOXO3,SLC35G1,CAMK2N2,LIMS1,PPM1L,SAMD5,FITM2,APTX,ZSCAN2,GTDC1,ALG9,PGBD4,HSD11B1L,AMBRA1,WDR37,PEX26,SP2,AGTPBP1,ARL10,SSBP2" MicroRNA hsa-miR-5590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.04E-13 2.26E-09 7.66E-13 7.06E-12 34 212 "CC2D2A,SEMA7A,CALM1,RIMS4,UBXN2A,FAM107B,CERCAM,RCAN2,DLC1,FOXO3,C15orf41,LUZP2,FUT10,MAT2A,MKLN1,PDE4D,ZFYVE21,PDZRN4,PRKCB,PEX2,CEP97,FIGN,ALG9,ROBO1,FAM126B,ZBTB43,ANKRD28,TNS1,RGMB,SMUG1,UBE2H,ZNF711,SLC38A1,STOX2" MicroRNA hsa-miR-31-5p:Functional MTI Functional MTI miRTarbase 4.04E-13 2.26E-09 7.66E-13 7.06E-12 35 224 "PHF12,NUMB,ATP2A2,JAZF1,CCNT1,MAP4K4,RHOBTB1,DMD,MED12,RASA4,MTSS1L,FOXO3,NOP56,GLI2,PRRC2B,LILRA2,ZNF678,STMN1,PPM1L,AFF1,MMP16,ZIK1,RDX,RET,MCMBP,ZNF331,MPRIP,SATB2,TIAM1,TMEM9,RPL7L1,DPYSL5,EMSY,PARP11,FZD3" MicroRNA hsa-miR-619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-13 2.35E-09 7.97E-13 7.33E-12 50 425 "ZNF578,TAOK1,LDHD,AP1M1,PLAA,CRY2,RGS6,CSNK1E,PPP1R16B,UBXN2A,DNAL1,SLC12A6,IRAK4,MRPL37,VPS26C,TLR7,CEP78,GTF2IRD2,FOXO3,TRAF3IP2,MTHFD2,KIAA1841,TXNL4A,CRCP,POLL,BVES,ZDHHC15,NEGR1,IL6R,CYP27C1,GPR155,MBD1,CHST6,MINDY2,C12orf49,PGBD4,HSPA4L,PEX26,FAM126B,SP2,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,ZNF70,ZBTB38,MPPE1" MicroRNA hsa-miR-122:PITA hsa-miR-122:PITA_TOP PITA 4.22E-13 2.36E-09 8.00E-13 7.37E-12 24 105 "ADGRB2,CACNB4,CS,IST1,SPOCK2,FOXO3,TNRC6A,BACH2,NEGR1,MARK1,MEIS2,OCRL,ZNF827,NLGN3,PTPRB,PPM1E,ARX,SLC4A3,FAM219A,SOX11,TCF4,DICER1,MAP3K12,ADAMTS10" MicroRNA hsa-miR-28-5p:PITA hsa-miR-28-5p:PITA_TOP PITA 4.59E-13 2.57E-09 8.69E-13 8.00E-12 29 156 "PDZD4,AMPH,SEMA4G,CACNA1G,LDLRAD4,CABP7,DCLK1,CNTFR,SH2B1,GDA,GAPVD1,DPP6,EPHB1,FOXO3,SYT3,CHL1,SESN1,RNF165,MAT2A,NFE2L2,NNAT,TMEM260,RDX,SMARCC2,SPTB,SYN2,TRPS1,KAT6A,JMJD1C" MicroRNA hsa-miR-383-5p.2:TargetScan hsa-miR-383-5p.2 TargetScan 4.65E-13 2.60E-09 8.80E-13 8.10E-12 30 167 "HECW2,PCDH19,DPP10,NRP2,RUNX1T1,FOXN3,PLCXD3,JAKMIP2,HIPK3,PAN3,GPHN,FECH,PPARGC1A,GRIA2,AGFG1,NKD1,MAP2,NNAT,KANSL1,MAPK10,GSTCD,RORB,SATB1,CDK19,DIP2A,ANKRD28,ITGB3BP,CBX5,RGS7BP,MSRB3" MicroRNA "TGTATGA,MIR-485-3P:MSigDB" "TGTATGA,MIR-485-3P:MSigDB" MSigDB 4.66E-13 2.61E-09 8.81E-13 8.11E-12 27 135 "ARHGAP20,PPP4R4,RUNX1T1,ZMYM4,TMEM184B,CNR1,GDA,SNPH,HDAC4,DAPK1,YAF2,UBE2E3,ZMAT1,CPLX2,PPARGC1A,STMN2,MEIS2,PDE4D,PURG,RBBP6,RFX3,KIF21A,SOX11,SYPL1,PUM2,SIRT1,ZIC2" MicroRNA "GCTCTTG,MIR-335:MSigDB" "GCTCTTG,MIR-335:MSigDB" MSigDB 5.09E-13 2.85E-09 9.62E-13 8.86E-12 21 79 "CERS5,FAM131B,LONRF1,FAM107B,ABCC5,PHF20L1,GLYR1,KDM2B,KAT7,ZHX1,MAP2,PCDH9,ZDHHC8,EPB41L4B,POU6F1,ZSWIM8,KDM4C,SYN2,RPRM,UBE2H,POLR3H" MicroRNA hsa-miR-924:PITA hsa-miR-924:PITA_TOP PITA 5.17E-13 2.89E-09 9.77E-13 9.00E-12 28 146 "SPOP,CDC42BPA,CDC14B,NCOR2,DOCK4,NYAP1,GOLT1B,EBF1,APH1A,RGS17,FOXO3,ZIC5,MAP2,MEIS2,ZC3H12B,NDP,PDE3A,PIK3R1,PMP22,RGS4,SEMA6D,FAM214B,SOX11,ARHGAP26,CUX2,TMEM121,FLRT2,CELF4" MicroRNA hsa-miR-132*:mirSVR_highEffct hsa-miR-132*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.27E-13 2.95E-09 9.96E-13 9.17E-12 24 106 "SYS1,FAM131A,CAST,DGKI,SRSF11,SRP14-AS1,DPH1,YAF2,GOLGA7,FAM198B,MALT1,GNAO1,GPD2,NF1,PCDH9,PCSK5,POLR2F,KANSL3,SNAP25,TPCN2,PMS2CL,PIK3R5,TRPS1,ADAMTSL3" MicroRNA "AGGAAGC,MIR-516-3P:MSigDB" "AGGAAGC,MIR-516-3P:MSigDB" MSigDB 5.27E-13 2.95E-09 9.96E-13 9.17E-12 24 106 "ASIC1,MTUS1,OGT,CCPG1,RIMS2,FAM131B,TM9SF4,PITPNC1,DCTN4,BAIAP2,GFRA2,CCDC184,PDE4A,POU6F1,GTDC1,S100B,SPTB,PLCB1,SYT1,SATB2,TCF12,OSBP2,ADAMTS9,SOCS4" MicroRNA hsa-miR-1269:PITA hsa-miR-1269:PITA_TOP PITA 5.73E-13 3.21E-09 1.08E-12 9.97E-12 25 116 "BACH1,QKI,AHCTF1,ZNF385A,CLOCK,YTHDC1,EMX2,OLFM1,PCDH17,ZHX1,PDE4D,PMP22,RAP1GDS1,FBXO11,SNAP25,SPTB,NSFL1C,NECAB1,ANKRD28,TCF4,TCF12,ZFPM2,RIMBP2,TMEM237,NAV3" MicroRNA hsa-miR-491-5p:PITA hsa-miR-491-5p:PITA_TOP PITA 6.56E-13 3.67E-09 1.24E-12 1.14E-11 24 107 "ZBTB10,ADGRB1,CFL2,ZNF385A,SEC24C,C2CD2L,DMPK,APH1A,EGR3,TMEM35A,AGAP3,SRCAP,TNRC6A,KAT7,MIER3,MAT2A,MEIS2,MN1,GIT1,PDE1B,FAM126B,STAC2,SYN1,CAMTA1" MicroRNA hsa-miR-543:Functional MTI Functional MTI miRTarbase 6.56E-13 3.67E-09 1.24E-12 1.14E-11 24 107 "ADD1,AMPD3,EIF4G3,BACH1,CLTC,SOCS5,RUBCN,MATR3,FAM13A,NCOA7,MN1,PTK2,SPDL1,STX1B,MYO18A,SHC4,FBXO11,FNDC3A,SYNE2,ADAMTS17,MTCL1,SIRT1,ZNF711,EML6" MicroRNA hsa-miR-216b-5p:Functional MTI Functional MTI miRTarbase 6.75E-13 3.77E-09 1.27E-12 1.17E-11 27 137 "AS3MT,FZD9,PDZD4,CDC42BPA,APAF1,ZNF583,ZBED1,SOCS6,UBXN2A,CENPL,TM9SF4,MRNIP,C8orf37,NKD1,ZIC5,SMAD1,MID1,P2RX7,PRKAB2,SP4,DNAJC9,SLC19A3,SSBP2,WRN,ZBTB38,ZFAND5,MPPE1" MicroRNA hsa-miR-6739-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-13 3.89E-09 1.31E-12 1.21E-11 33 204 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,PRRC2B,NEGR1,KCNB1,OCRL,ZNF827,WBP1L,BDNF-AS,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,PEX26,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,NR2E1,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-3926:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.06E-13 3.95E-09 1.33E-12 1.23E-11 41 305 "PLEKHH1,KIAA1324,SEMA7A,BACH1,CBS,CCNT1,LRIG1,CTH,GREB1,YTHDC1,MRO,COQ7,ZNF549,POLR1B,GATM,GLUL,LUZP2,RNF165,HLF,ZNF678,MAPT,SAMD5,SFR1,SLC11A2,STRN3,PTPRB,CEP97,MRPS18A,SNX22,PREX2,DDN,NEK4,TBCEL,USP22,ZMAT3,ZNF610,VLDLR,TBC1D15,ZNF17,ZNF70,TMEM237" MicroRNA hsa-miR-6128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.12E-13 3.98E-09 1.34E-12 1.24E-11 23 98 "BEND6,ATP1B3,CLCN3,TMEM184B,RIMS4,DCAF4,SNX29,EPB41,COQ7,CRCP,CYP27C1,C1orf109,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,AGTPBP1,TMPO,PPIL6,SSBP2,NDRG4,SLC30A4" MicroRNA hsa-miR-1247:mirSVR_lowEffct hsa-miR-1247:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.86E-13 4.40E-09 1.48E-12 1.36E-11 41 306 "AP2A2,SHROOM2,NRP2,CBS,CHRNA4,ANKRD35,PHACTR3,DCAF4,KIF26A,TENM1,RASL12,REEP2,TAOK3,AGAP2,RASL10A,PRELID3A,BRSK1,FAM120B,ADAMTS13,RTL5,RGS12,STX1B,ZNF331,WDR37,EPN2,CPEB4,SNRPN,DOP1A,TMEM150C,ADGRL3,ZNF346,NEIL2,TTTY15,HSPBP1,KLC2,ZNF708,NDRG4,MEIS3,RNF103,SEMA3B,EPM2A" MicroRNA hsa-miR-5093:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.63E-13 4.83E-09 1.63E-12 1.50E-11 25 118 "OGT,WASF1,ISPD,CBS,KIAA0408,SUCO,GPT2,ZIC5,TJAP1,AFF1,GPR137C,LRP12,EPB41L4B,CNNM2,C1orf109,PGBD4,ATXN7,HSPA4L,LHPP,ZSCAN29,TBCEL,ZNF34,WNT7A,ZNF28,HNRNPA3" MicroRNA hsa-miR-6828-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.73E-13 4.88E-09 1.64E-12 1.51E-11 28 149 "SLC24A4,OGT,USP37,ATP1B3,BCL7A,PPP1R16B,EPB41,ZNF391,ZNF585B,DLC1,FOXO3,CYP46A1,ZNF678,MITF,PLXNB1,SETD5,ZNF331,R3HDM2,TMCC1,SYPL1,TAF6,TRIM2,BHLHB9,SMUG1,TUBB2A,BCL2L13,FBXO36,SPATA13" MicroRNA hsa-miR-604:mirSVR_highEffct hsa-miR-604:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.95E-13 5.01E-09 1.69E-12 1.55E-11 23 99 "ABHD6,ATP2A2,ARHGEF7,ENTPD6,SMARCAL1,ZNF521,CDC42BPB,HDAC4,PLEKHA1,TAOK3,SPECC1,SULT1C4,GRB10,GRIK5,AP4S1,NOVA1,ANKRD16,ATAT1,SEPT3,TPM1,LGI4,TMEM198,SEMA3B" MicroRNA "CAATGCA,MIR-33:MSigDB" "CAATGCA,MIR-33:MSigDB" MSigDB 9.20E-13 5.15E-09 1.73E-12 1.59E-11 22 90 "OGT,CAMK2G,USP6,CHN2,MAP4K4,SEC24C,CNNM1,OLFM1,PPARGC1A,ICA1,MEIS2,MMP16,NFIX,NPY,SNRK,FBXW7,SCN8A,CASC3,SOX11,SATB2,USP32P2,DPYSL5" MicroRNA hsa-miR-5003-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.70E-13 5.43E-09 1.83E-12 1.68E-11 27 139 "RNF150,OSBPL1A,ABCD2,USP37,CSNK1G3,VCAN,MAML1,PITPNC1,EBF1,FEM1B,SARAF,HHIPL1,SYT17,HAS2,KCNN3,L1CAM,LIFR,GLIPR1L2,STRN3,NWD1,ZFHX4,CCDC25,ZBTB43,SGK3,ZNF610,WRN,ZBTB38" MicroRNA hsa-miR-875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-12 5.65E-09 1.90E-12 1.75E-11 24 109 "BEND6,MTA3,ATP1B3,ISPD,CLCN3,TMEM184B,DCAF4,EPB41,CELF1,ZNF44,CYP27C1,PLEC,C1orf109,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,TBCEL,TMPO,SSBP2,ZKSCAN5,NDRG4,SLC30A4" MicroRNA hsa-miR-1909*:mirSVR_highEffct hsa-miR-1909*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-12 5.65E-09 1.90E-12 1.75E-11 40 295 "NCKAP5,SMIM17,ZNF687,APC,CA4,KALRN,CDO1,RCBTB2,SRP14-AS1,SLITRK5,USP6NL,HDAC9,BRINP1,DCTN4,GMPR2,C2orf88,RAPGEF6,KIAA1841,RAB30,WDFY3-AS2,LRRC75A,MATN2,MEF2C,ADAM22,FSD1,SAMD9,CCDC82,SEMA6D,PEAR1,CNKSR2,NUBPL,DHX30,CDK5RAP3,ATP10B,SYNE2,ARHGEF9,ADGRL3,TCF12,DICER1,LRRC8A" MicroRNA hsa-miR-766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-12 5.68E-09 1.91E-12 1.76E-11 35 231 "RNF157,HACE1,SORCS2,PHF12,ARHGDIA,CBS,EVI5L,CS,CSF1,PHC2,MTSS1L,TMEM164,GLYR1,STARD3,ZNF496,ZBTB45,LINGO1,NEGR1,SHISA6,NOVA2,KSR2,PKM,SMIM7,PLXNB1,POLG,EMID1,SOX11,PEG10,DBNDD2,ASTN2,HIF3A,NACC2,WBP2,WRN,ZNF17" MicroRNA hsa-miR-93-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-12 5.75E-09 1.93E-12 1.78E-11 38 269 "ABR,ACTN1,ATP1A1,CBR1,LRBA,PLXNA4,DCAF8,SV2B,HEYL,EEF1D,ENO2,MTSS1L,FER,RGPD5,FYN,ZNF44,SRCAP,GPR162,CRCP,DIDO1,CIT,MYCN,SLC25A23,NCBP3,SCN7A,PEAR1,PUF60,DHX30,KANSL3,ARFGAP1,SPTAN1,SUPT5H,TIAM1,PARD3,TRIO,RUNDC3B,EIF4ENIF1,SLC35A4" MicroRNA hsa-miR-548az-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-12 5.75E-09 1.93E-12 1.78E-11 38 269 "PTBP2,SRSF11,QKI,TOGARAM2,CLOCK,SOCS5,PYGO1,YTHDC1,DPYSL2,KATNAL1,ACSL4,DLC1,SUCO,TPK1,ZMAT1,TNRC6A,PRRC2B,GRB10,MAP4K5,SOWAHA,STMN1,TM6SF1,CNOT4,PFKFB2,PFKFB3,SH3KBP1,SLC25A36,C12orf49,MCMBP,ATAT1,DHX33,CADM2,ADAMTS9,PPP1R3F,ITM2C,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-548t-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-12 5.75E-09 1.93E-12 1.78E-11 38 269 "PTBP2,SRSF11,QKI,TOGARAM2,CLOCK,SOCS5,PYGO1,YTHDC1,DPYSL2,KATNAL1,ACSL4,DLC1,SUCO,TPK1,ZMAT1,TNRC6A,PRRC2B,GRB10,MAP4K5,SOWAHA,STMN1,TM6SF1,CNOT4,PFKFB2,PFKFB3,SH3KBP1,SLC25A36,C12orf49,MCMBP,ATAT1,DHX33,CADM2,ADAMTS9,PPP1R3F,ITM2C,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-4668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-12 5.76E-09 1.93E-12 1.78E-11 30 172 "SPOP,TRMT9B,ASGR1,BMPR1B,CCNT1,QKI,CENPL,GUCD1,RCAN1,EDN3,FSD1L,EIF4G2,CEP85L,TMEM164,AMOTL2,IP6K2,ST6GALNAC3,CRCP,GPR75,RNF165,HAS2,USP51,MEIS1,CLIP1,FNDC3A,SLC8A1,ARC,TACC1,CBX5,LYPD6" MicroRNA hsa-miR-378a-3p:TargetScan hsa-miR-378a-3p TargetScan 1.05E-12 5.89E-09 1.98E-12 1.82E-11 29 161 "ADD2,PTCHD1,CDC42BPA,C6orf89,EIF4G3,KSR1,MROH8,RIMS4,MED12L,CAMKK2,AP4B1,PTPRT,GSTM5,IGF1,IL6ST,KCND1,KIF2A,NOVA2,PDE1B,PDPK1,PEX2,RASGRF1,AP1AR,CSRNP3,IQSEC2,NSFL1C,ARL10,CBX5,LAS1L" MicroRNA hsa-miR-6736-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-12 6.08E-09 2.04E-12 1.88E-11 36 244 "CLK4,MTA3,STX16,MTMR3,CBS,NDST3,RTTN,UBXN2A,ZBTB24,ELMO1,MRNIP,RGS17,IGSF6,RAPGEF6,KDM2B,LILRA2,PTPRT,KAT7,GPR155,SAMD5,CDK18,FITM2,ZNF793,PGBD4,SEMA6D,PEX26,TRIM67,ATF7IP,ZNF621,POGZ,SSTR2,ALG1,AGTPBP1,SLC19A3,CBX5,UPF3A" MicroRNA hsa-miR-3131:mirSVR_highEffct hsa-miR-3131:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-12 6.28E-09 2.10E-12 1.94E-11 23 100 "DNM1L,APH1A,EIF1,CLVS1,CELF1,STARD3,FERMT2,ELOVL5,SMAP1,KIFC3,NLGN3,MTRF1L,TTC13,GTDC1,EXD2,MTCL1,RPGRIP1L,SYNE1,TLR4,RIMBP2,C9orf85,TRPS1,OSBP2" MicroRNA "CTGTTAC,MIR-194:MSigDB" "CTGTTAC,MIR-194:MSigDB" MSigDB 1.12E-12 6.28E-09 2.10E-12 1.94E-11 23 100 "PITPNM2,STX16,MYRF,LRRFIP1,QKI,ELMSAN1,DMD,HS3ST2,DUSP9,MBNL2,PAN3,GABRB3,TJAP1,MEIS2,PFKFB2,ZFHX4,FBXW7,CHD9,SEPHS1,BTBD7,CDK19,TRPS1,TRIM9" MicroRNA hsa-miR-4287:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-12 6.46E-09 2.17E-12 1.99E-11 38 270 "XKR4,ADCY5,ADCY6,MTA3,AK2,OGT,SEMA4G,ARSE,BACH1,CCNT1,QKI,LRIG1,PITPNM3,PLCXD3,CYBB,SPATA2,EMX2,SLC43A2,SRRM4,ZNF638,BACH2,MIER3,SHISA6,KCNQ3,LSAMP,MBNL1,MYO5A,GPR137C,MTMR10,PTPRG,GTDC1,ATXN7,DIP2A,IQCE,RUNDC3B,TMEM198,RNF146,GAN" MicroRNA hsa-miR-548p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-12 6.87E-09 2.30E-12 2.12E-11 28 151 "FAM135A,DST,HINFP,UBXN2A,DCAF8,SPATA2,TMTC1,MTHFD2,NKD1,IL6ST,KCNN3,LAMP2,GPR137C,GPR85,LRP12,CNNM2,KLHL11,CSRNP3,ATF7IP,PEG10,CDK19,SYPL1,CLASP1,ZMAT3,CBX5,TUBB2A,RPL7L1,NDRG4" MicroRNA hsa-miR-5582-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-12 6.93E-09 2.32E-12 2.14E-11 29 162 "QKI,CLOCK,C2CD2,CRY2,IPCEF1,SEC14L5,SEC16A,DNAH9,E2F6,POLR1B,ZBED3,KAT7,ZNF678,NCAM2,NFIX,KSR2,ATAT1,SBF1,SH3BP2,R3HDM2,BTBD3,SLC8A1,UNC5B,NECAB1,SYPL1,GALNT17,WRN,CLDND1,SIGLEC10" MicroRNA hsa-miR-1258:PITA hsa-miR-1258:PITA_TOP PITA 1.25E-12 7.00E-09 2.34E-12 2.16E-11 26 130 "OSBPL8,ARMC8,KCTD8,ELMSAN1,EMX2,FGF12,FOXO3,PPARGC1A,GPT2,ADAMTS6,ZIC5,LAMP2,MBP,NEXMIF,GNG2,PMP22,PPP2R5E,GTDC1,ZFHX4,KIF21A,ABLIM3,SP4,SYT1,TCF12,R3HDM1,UBE2H" MicroRNA hsa-miR-1293:PITA hsa-miR-1293:PITA_TOP PITA 1.29E-12 7.22E-09 2.41E-12 2.22E-11 20 74 "ELFN2,RTL9,SEMA6A,SEMA4G,NOG,CNR1,EIF4G1,PPARGC1A,MEIS1,MEIS2,NEXMIF,CNOT4,SH3KBP1,PSD,GTDC1,ZFHX4,ROBO2,NCBP3,CLASP2,POLR3H" MicroRNA hsa-miR-191-5p:TargetScan hsa-miR-191-5p TargetScan 1.35E-12 7.57E-09 2.53E-12 2.33E-11 16 44 "PITPNM2,CASK,ATP2B2,PITPNM3,LIN54,PHC2,EMX2,NEURL4,GLYR1,NRCAM,PLCD1,RFX3,SATB1,SATB2,LRRC8A,JPH3" MicroRNA hsa-miR-412:PITA hsa-miR-412:PITA_TOP PITA 1.39E-12 7.76E-09 2.59E-12 2.39E-11 27 141 "FMNL2,HECW2,SEMA6A,PKP4,NCOA1,QKI,SLITRK5,ELMSAN1,APH1A,MBNL2,TAOK3,SPIN1,GPD2,RNF165,SLC6A17,ZNF827,SNRK,ROBO1,SATB1,NLGN1,PEG10,NKAIN2,ERBIN,EXOC7,TMEM237,POLR3H,ST8SIA2" MicroRNA hsa-miR-561-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-12 7.76E-09 2.59E-12 2.39E-11 27 141 "GALNT13,TAOK1,PCDH10,CADPS,CNN3,USP6NL,LONRF1,DMD,TMTC1,CELSR3,RCAN2,FUT10,NEGR1,RBPJ,CHIC1,ZNF713,PTCH1,ROBO1,FNDC3A,CPEB4,TROVE2,SYPL1,ANKRD28,RUNDC3B,VLDLR,ZNF138,FXR1" MicroRNA hsa-miR-621:PITA hsa-miR-621:PITA_TOP PITA 1.40E-12 7.85E-09 2.62E-12 2.42E-11 23 101 "ACTN1,CCDC85A,PCDH19,DCLK1,CFL2,FOXN3,AKAP3,GPD2,ZHX1,MIER3,MEF2C,KITLG,NEXMIF,ZC3H12B,GPR85,PFKFB3,PTPRD,RDX,ZFHX4,WDR37,SLC12A2,HECW1,ZNF346" MicroRNA hsa-miR-512-5p:PITA hsa-miR-512-5p:PITA_TOP PITA 1.45E-12 8.13E-09 2.71E-12 2.50E-11 28 152 "TAOK1,LURAP1,SPAG9,DLGAP2,GDA,CNTNAP2,KIAA0753,SNAP91,MTX3,DMD,EMX2,PCDH17,KCND2,MAP2,MN1,NEXMIF,NFIX,PCSK1,PIK3R1,RASGEF1B,COPZ1,CHD9,FBXW11,TCF4,ZFPM2,FAM155A,PDSS2,PHTF2" MicroRNA hsa-miR-517b:mirSVR_highEffct hsa-miR-517b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-12 8.14E-09 2.72E-12 2.50E-11 29 163 "FMNL2,ABI3BP,AHCTF1,ERC2,BOC,MATR3,GSDME,EGFR,CLVS1,CORO2B,ATP2C1,ZNF559,DISC1,HPGDS,GPD2,MSL1,KCNJ16,VPS13C,PTPRD,PTX3,RASGRF2,C12orf49,SHC4,TMEM150C,TSC1,TMEM198,PRDM8,MPPE1,CPNE4" MicroRNA hsa-miR-1252-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-12 8.14E-09 2.72E-12 2.50E-11 29 163 "TRMT9B,BCL7A,CNGA3,CRY2,LONRF1,CHRDL1,PHC2,EIF1,PRRC2B,TNFAIP8L3,MAN2A2,ZFYVE27,MKLN1,MYCN,ZNF827,SNX10,FIGN,UBR7,SETD5,SGK1,LGI3,IQSEC2,MPRIP,TAF6,HIF3A,WBP2,WRN,ITM2C,SPATA13" MicroRNA hsa-miR-188-5p:TargetScan hsa-miR-188-5p TargetScan 1.46E-12 8.14E-09 2.72E-12 2.50E-11 29 163 "MAGI1,IGLON5,PCYT1B,HDAC9,ELMSAN1,GUCD1,NBEA,FRMD5,AGFG1,NKD1,IL6ST,CDH20,MEF2C,MGAT3,MXI1,PDE4A,RAD51D,ROBO2,FBXW7,ATXN7,FNIP1,HSPA4L,ABLIM3,ANKRD12,FAM208A,ASXL3,RICTOR,EVI5,RNF170" MicroRNA hsa-miR-6796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-12 8.32E-09 2.78E-12 2.56E-11 22 92 "XKR4,CDC14B,RUNX1T1,KIAA0408,KIAA0319,FGFR3,ZBED3,MSANTD4,GSTM5,LIMS1,MAP4,MMP16,PAX6,EPB41L4B,AMBRA1,MBD5,ZNF621,ITPRID2,ARL10,ERCC6L2,PARD3,CCDC14" MicroRNA hsa-miR-455-5p:TargetScan hsa-miR-455-5p TargetScan 1.52E-12 8.48E-09 2.83E-12 2.60E-11 31 186 "C3orf14,GALNT13,KCTD16,PHF12,CDK13,LDLRAD4,CACNB4,CAST,FOXN3,CLOCK,RIMS4,PLCXD3,MFAP3L,EBF1,PLXNC1,ERBB4,INPP5K,RNF165,FICD,HAS2,FRMD5,KLHL23,LAYN,FIGN,CPEB3,R3HDM2,EPN2,CPEB4,CLSTN2,DOCK9,CDH22" MicroRNA hsa-miR-6783-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-12 8.48E-09 2.83E-12 2.60E-11 31 186 "ELFN2,TRMT9B,PPFIA3,ARRB2,CBS,METTL6,ZNF385A,TMCC2,HEYL,APH1A,MRO,IRAK4,ZNF496,DDX19B,KCND1,ZFYVE27,MAT2A,OGG1,PDE4D,EPB41L4B,TMEM145,HKR1,PKNOX2,COA1,ZNF423,SPART,MPRIP,ASXL3,TNS1,UBTF,BCL2L13" MicroRNA hsa-miR-670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-12 8.83E-09 2.94E-12 2.71E-11 32 198 "C3orf14,XKR4,C1QTNF3,TNRC6C,LDHD,LDLRAD4,RUNX1T1,LONRF2,IGDCC3,PDE4DIP,PLCXD3,USP3,DPYSL2,EDN1,TMTC1,C8orf37,ERBB2,MRPL37,SCML2,TXNL4A,MAT2A,MBNL1,MID1,ZNF844,ELP2,NLGN1,SLC2A5,ZNF138,TFIP11,FAM13C,JMJD1C,FRMD6" MicroRNA hsa-miR-6733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-12 8.83E-09 2.94E-12 2.71E-11 32 198 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,PRRC2B,NEGR1,KCNB1,OCRL,ZNF827,WBP1L,BDNF-AS,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,PEX26,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-3153:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-12 8.83E-09 2.94E-12 2.71E-11 32 198 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,PRRC2B,NEGR1,KCNB1,OCRL,ZNF827,WBP1L,BDNF-AS,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,PEX26,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-602:mirSVR_highEffct hsa-miR-602:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-12 9.25E-09 3.08E-12 2.83E-11 27 142 "ALCAM,PCDH10,PITPNM2,ZBTB10,SLC25A14,ZMYM4,NOG,KMT5B,RASGRP2,FOXF2,MID1,MMP16,MSR1,NRCAM,NUCB2,GPR85,GNG2,PURG,CNNM2,TMEM260,SLC12A4,NAPB,SNAP25,KDM4C,RGL1,DNMBP,KCNAB1" MicroRNA "GAGCCTG,MIR-484:MSigDB" "GAGCCTG,MIR-484:MSigDB" MSigDB 1.75E-12 9.79E-09 3.26E-12 3.00E-11 23 102 "PCDH19,SEMA4G,GAPVD1,DPYSL2,PHC2,FAM13A,EZH1,FGF1,SCARA3,GRB10,ZIC5,RETREG1,CEP41,PRKCB,PTPRE,PRRT2,GTDC1,ZNF667,MYCBP2,KIAA0930,TRPS1,PLEKHH2,ZIC1" MicroRNA hsa-miR-3685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-12 9.79E-09 3.26E-12 3.00E-11 23 102 "ADD2,GAS7,MARK4,ATP1A1,RUNX1T1,LONRF2,CNN3,EPB41,COQ7,MRVI1,SMC2,SRRM4,GPR155,NFIX,KANSL1,MARCH1,KIRREL1,SCN2B,ZFP30,ST6GAL1,TPM1,TRPS1,RICTOR" MicroRNA hsa-miR-25*:mirSVR_highEffct hsa-miR-25*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-12 1.01E-08 3.37E-12 3.10E-11 26 132 "LRFN2,AMPD2,SUGT1P4-STRA6LP-CCDC180,MARCH3,CST3,DPH1,SRRM1,ZNF589,RASL10A,ATP6V1H,GHR,NRBP2,NCAM2,APTX,RGS3,KCTD17,TMLHE,RPS20,KANSL3,KDM4C,PRRT1,SSBP2,ANKS1B,PRTFDC1,PPP1R3F,ST7" MicroRNA hsa-miR-630:PITA hsa-miR-630:PITA_TOP PITA 1.82E-12 1.02E-08 3.38E-12 3.11E-11 32 199 "LRCH2,MAP4K3,APBA2,CADPS,ATP1A1,CDH2,CFL2,QKI,TMEM184B,ANKRD44,ARHGAP24,KLHL3,PCLO,GRIA2,BACH2,MIER3,HMGCR,KCND2,STXBP5,MEIS2,PCDH9,PID1,OXR1,RASGRF1,SLC25A36,CHD9,CPEB4,LMO3,PLCB1,FLRT2,SLC38A1,PHTF2" MicroRNA hsa-miR-4321:mirSVR_highEffct hsa-miR-4321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-12 1.02E-08 3.38E-12 3.11E-11 19 67 "PTCHD1,RTL9,MTMR2,ARMCX4,STAU2,FYB1,GALNT15,DISC1,GHR,TXNL4A,DIDO1,MARK1,PCDH18,RORB,RPL15,MEG3,TET1,MTCL1,TRO" MicroRNA hsa-miR-1207-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-12 1.05E-08 3.49E-12 3.21E-11 21 84 "ZNF578,ARHGAP22,ENTPD4,CRY2,CSNK1E,PPP1R16B,KIAA0408,YTHDC1,REEP2,PCYOX1,ZFYVE27,NBL1,NLE1,ZMAT4,SETD5,ZFP30,GPRIN3,ZNF106,SMUG1,URM1,MPPE1" MicroRNA hsa-miR-644a:Functional MTI Functional MTI miRTarbase 1.88E-12 1.05E-08 3.50E-12 3.22E-11 22 93 "ELFN2,CARNS1,LDHD,CACNA1A,TMEM184B,IGLON5,ENTPD4,DCAF8,TMEM130,DMTF1,C8orf37,MRPL37,CAMKK2,PRRC2B,NKD1,MAP2,MPP2,SDK2,SATB1,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-3196:mirSVR_highEffct hsa-miR-3196:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.90E-12 1.06E-08 3.53E-12 3.25E-11 25 122 "SUGT1P4-STRA6LP-CCDC180,PPFIA3,ZSCAN18,SEC11C,DDR1,CABP1,CYBB,GTF2IRD2,PSD2,ARHGAP36,MEIS1,NPTX2,ZNF827,NALCN,EXOSC10,LGI3,SLC22A4,SMARCC2,TAF6,PRRT1,ATP6V0E2,ANKS1B,DHX33,CASC15,ADAMTS10" MicroRNA hsa-miR-1224-5p:PITA hsa-miR-1224-5p:PITA_TOP PITA 1.90E-12 1.06E-08 3.53E-12 3.25E-11 25 122 "MAP4K3,THSD7A,RUNX1T1,DCLK1,CRY2,GRIN3A,CPLX2,GPD1,ZHX1,GABARAPL2,CHIC1,KITLG,NOVA1,MAPK10,GTDC1,SATB1,SCP2,NFASC,TRPS1,TUBB2A,EIF4ENIF1,UCHL1,DPF3,RNF146,SENP7" MicroRNA hsa-miR-4302:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-12 1.10E-08 3.65E-12 3.36E-11 27 143 "ELFN2,SLC24A4,SFMBT2,LDHD,EVI5L,SEC16A,ELN,C8orf37,CELF1,GCK,MAT2A,POLR2F,ZNF844,QDPR,SLC25A36,KIAA0895L,SGK1,SLC2A5,PEX26,ZFP1,CXXC4,ZNF415,ITPRID2,PRRC2C,CCDC14,ZNF24,ZNF195" MicroRNA hsa-miR-331-3p:TargetScan hsa-miR-331-3p TargetScan 2.00E-12 1.12E-08 3.71E-12 3.41E-11 29 165 "RNF150,AP2A1,CASK,ARRB1,NRP2,KSR1,HAP1,IGLON5,MYRIP,RIMS4,ELMSAN1,PHC2,ELN,FGF11,CPLX2,ATOH8,CHIC1,MEIS1,MEIS2,MSI1,NOVA2,PTPRD,C1orf109,RIC8B,CASC3,ANKRD6,EXOC7,FAM208A,POLR3H" MicroRNA hsa-miR-4667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-12 1.12E-08 3.72E-12 3.42E-11 36 249 "ARRB1,ARSE,GPR146,BTK,STOML1,TOGARAM2,TMEM170A,EMX2,ANKMY1,PDLIM5,GABRG2,RAB30,KIAA1958,MAP4K5,KIFC3,CYP27C1,LSAMP,MYO5A,NEXMIF,GTDC1,CYB561D1,RXRA,STX1B,WDR37,BTBD3,MAPKBP1,ZSCAN29,NSFL1C,SZT2,NSD1,CRTC1,KCNK12,AMZ1,ZNF225,URM1,JPH3" MicroRNA "AGTTCTC,MIR-146B:MSigDB" "AGTTCTC,MIR-146B:MSigDB" MSigDB 2.01E-12 1.13E-08 3.73E-12 3.43E-11 17 52 "PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP1,USP3,PHF20L1,KDM2B,MMP16,NOVA1,KCTD15,ZNF532,SNX22,SYT1,POLR3H" MicroRNA "AGTTCTC,MIR-146A:MSigDB" "AGTTCTC,MIR-146A:MSigDB" MSigDB 2.01E-12 1.13E-08 3.73E-12 3.43E-11 17 52 "PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP1,USP3,PHF20L1,KDM2B,MMP16,NOVA1,KCTD15,ZNF532,SNX22,SYT1,POLR3H" MicroRNA hsa-miR-3646:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-12 1.17E-08 3.87E-12 3.56E-11 32 200 "STX16,TOGARAM2,OSBPL3,SPATA2,E2F6,SEMA3D,CELF1,TUBGCP4,COPS8,TNRC6A,CIT,FICD,CLDN11,PDE4D,PSAT1,SH3TC2,ERI2,RFX3,ATAT1,TRA2B,HSPA4L,SGK1,BDP1,ITPRID2,ZMAT3,ZNF34,SLC44A1,UGT8,MFF,ZDHHC20,FXR1,NETO2" MicroRNA hsa-miR-425-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.34E-12 1.31E-08 4.33E-12 3.99E-11 27 144 "TAOK1,ZBTB10,INSYN2B,LDHD,BTK,CDC25B,FOXN3,QKI,ZC3H11A,EXOG,DPYSL2,FRY,FGFR3,SYNCRIP,STMN1,OCRL,PNMA8A,PPP4R3A,ZHX3,DICER1,BHLHB9,BEX4,RUSC1,RPL7L1,PLSCR4,KAT6A,GAN" MicroRNA hsa-miR-5680:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.34E-12 1.31E-08 4.34E-12 3.99E-11 31 189 "ARHGEF7,CSNK1E,UBXN2A,TMEM170A,FBXL5,EIF4G2,TENM1,DLC1,SYNCRIP,ZBED3,STAMBP,ADAP1,IL6R,NCOA7,MAT2A,MBNL1,PRKAB2,PTPRN2,ERI2,FIGN,CSRNP3,BTBD3,SLC6A8,KIF13A,SEPT8,TCEA1,SATB2,TUBB2A,VLDLR,ZNF711,SMARCAD1" MicroRNA hsa-miR-3192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-12 1.44E-08 4.75E-12 4.37E-11 38 277 "TRMT9B,CDC14B,ASPA,AP1M1,CDR1,EPS15L1,RGS6,GAPVD1,SGSM2,RASA4,MRNIP,MTSS1L,VPS26C,TRMO,MTHFD2,DISC1,CRCP,GLUL,POLL,KAT7,BVES,DDX19B,ZNF491,NEGR1,IBA57,MAT2A,NBL1,PKD1,QDPR,IQSEC3,PGBD4,FBXW7,HES6,PEX26,ATF7IP,SSBP2,ZBTB38,TMEM63C" MicroRNA hsa-miR-544a:TargetScan hsa-miR-544a TargetScan 2.57E-12 1.44E-08 4.75E-12 4.37E-11 30 178 "KCNH8,FMNL2,PTBP2,CAMK2B,RUNX1T1,KRIT1,LETMD1,PITPNM3,GAPVD1,JAKMIP2,E2F5,IRAK4,FLT1,RAPGEF6,GPT2,LNX1,KIF2A,BLOC1S2,NF1,NPTX1,NTRK2,ATXN2,ATXN7,CCDC88A,CPEB4,ANKRD12,FAM208A,RPGRIP1L,DOK6,HNRNPA3" MicroRNA "AACATTC,MIR-409-3P:MSigDB" "AACATTC,MIR-409-3P:MSigDB" MSigDB 2.61E-12 1.46E-08 4.82E-12 4.44E-11 26 134 "NDRG3,OGT,SRSF11,QKI,CLOCK,AKAP12,HDAC4,MATR3,MTX3,EDN1,IP6K2,MSTN,GPD2,FICD,BACH2,IGF1,PCDH9,PDE4B,SCHIP1,RIC8B,PBRM1,SEMA6D,USP33,ELOVL4,PUM2,TBC1D15" MicroRNA hsa-miR-4707-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-12 1.51E-08 4.99E-12 4.59E-11 23 104 "XKR4,ATP1B3,LDHD,ZMYM4,DIS3L,ENTPD4,PITPNM3,MYADM,DNAL1,MRPL37,SEC23B,KIAA1841,DDX19B,METTL21A,MBD1,GDPD1,HSPA4L,SEPT8,KLHL7,KIAA0930,SZT2,THRA,DPYSL5" MicroRNA hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA_TOP PITA 2.73E-12 1.53E-08 5.05E-12 4.65E-11 29 167 "TMEFF1,SPAG9,DLGAP2,CFL2,CNR1,CLOCK,EGR3,ERBB4,NBEA,CAMKK2,PCDH17,TNRC6A,TDRKH,IPO5,NCOA7,MEIS1,MSI1,PDE4D,WBP1L,RIC8B,NAPB,LARP4,TTBK2,TCF12,FRYL,SIRT1,TIAM1,TSN,SMARCAD1" MicroRNA hsa-miR-660:PITA hsa-miR-660:PITA_TOP PITA 2.73E-12 1.53E-08 5.05E-12 4.65E-11 29 167 "UNC79,PKP4,STX16,LDLRAD4,MAGI1,ARHGEF6,DGKB,ERBB4,NBEA,PPARGC1A,CIT,BVES,MIER3,LIFR,MEF2C,MEIS1,NPTX1,NRCAM,PCDH9,SH3TC2,RAP1GDS1,RFX3,ZNF532,SEMA6D,TCF4,SATB2,FAM155A,WNK3,SENP7" MicroRNA hsa-miR-8055:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-12 1.56E-08 5.14E-12 4.73E-11 41 318 "AS3MT,MTA3,TAOK1,CEP126,ISPD,CBS,CD86,TBRG4,AKAP5,RTTN,RNF14,USP6NL,LONRF1,JAKMIP2,CELSR3,PCYOX1,SRCAP,TNRC6A,GLUL,ZDHHC15,SCIN,IBA57,MBD1,MKLN1,TBC1D25,PDE3A,SMIM7,ZNF426,STRN3,CNTLN,MTMR10,MSANTD2,SETD5,ELP2,SCN2B,PDZD2,KIAA0930,TNS1,ZNF708,ZXDA,PHTF2" MicroRNA hsa-miR-483-3p.2:TargetScan hsa-miR-483-3p.2 TargetScan 2.79E-12 1.56E-08 5.15E-12 4.74E-11 25 124 "OGT,KSR1,CAMK2G,CCNT1,RCHY1,NRG2,IP6K1,MFAP3L,PHF20L1,ERBB4,ANKFY1,ATP2C1,GABBR1,PRUNE2,IGF1,CAMK2N2,MITF,AFF1,RPE,EPHA10,SATB1,FAM126B,CLSTN2,EXOC7,GAN" MicroRNA hsa-miR-4731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-12 1.57E-08 5.18E-12 4.77E-11 45 374 "ADD1,ZNF578,TAOK1,AMH,PPFIA4,ATP1B3,LDHD,METTL6,DIS3L,PLAA,IGDCC3,RGS6,SOCS5,UBXN2A,MYADM,DNAL1,SLC12A6,IRAK4,MRPL37,TLR7,GTF2IRD2,ZBED3,TRAF3IP2,KIAA1841,CRCP,HAS2,ZNF491,KCNH2,CYP27C1,GPR155,MBD1,CHST6,PKM,C12orf49,SBF1,GALNT10,HSPA4L,SP2,GPRIN3,ZMAT3,THRA,CBX5,PARD3,ZNF708,MPPE1" MicroRNA hsa-miR-6887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-12 1.74E-08 5.75E-12 5.30E-11 26 135 "HACE1,TRMT9B,PRX,ARHGDIA,BCL7A,CALM1,ZNF385A,PYGO1,ERBB2,MTHFD2,GCK,GFER,NXPH3,PLEC,ZNF426,SDK2,NCR3LG1,BDNF-AS,PRRT2,HSD11B1L,NMNAT2,NFASC,USP22,TUBB2A,RPRM,MGAT5B" MicroRNA hsa-miR-4267:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.30E-12 1.85E-08 6.09E-12 5.61E-11 28 157 "NCKAP5,ZNF578,ABCD2,SEMA7A,GYG2,CBS,LRRFIP1,NDST3,ARHGAP22,PLXNA4,ELMO1,EPB41,PDLIM5,RAPGEF6,PARD3B,SLC6A17,ZFYVE27,CCSER2,MTRF1L,ALG9,FAIM2,APOM,KIAA0930,CYB561A3,CBX5,CLDND1,WNK2,RNF146" MicroRNA hsa-miR-548t-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-12 1.93E-08 6.36E-12 5.85E-11 30 180 "XKR4,SLC24A4,TNRC6C,ZNF385A,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,GPR85,PPP2R2B,NWD1,ROBO1,SALL1,TRA2B,BTBD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA hsa-miR-548ap-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-12 1.93E-08 6.36E-12 5.85E-11 30 180 "XKR4,SLC24A4,TNRC6C,ZNF385A,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,GPR85,PPP2R2B,NWD1,ROBO1,SALL1,TRA2B,BTBD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA hsa-miR-99a*:mirSVR_highEffct hsa-miR-99a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.45E-12 1.93E-08 6.37E-12 5.86E-11 24 115 "TTLL9,ARHGEF7,RUNX1T1,AKAP7,CREM,HS3ST2,FCF1,MEX3B,EFCAB2,OGA,ZNF276,TCERG1,NCKAP1L,KCNQ3,TMEM255A,RBBP6,ATXN7,CNKSR2,ZC3H4,TIAM1,TMPO,DCBLD1,WIPF1,PRTFDC1" MicroRNA hsa-miR-5589-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.48E-12 1.95E-08 6.41E-12 5.90E-11 42 334 "ZNF578,TAOK1,CEP126,PPFIA4,ARHGDIA,ATP1B3,LDHD,DIS3L,PLAA,IGDCC3,SOCS5,UBXN2A,DNAL1,SLC12A6,IRAK4,MRPL37,TLR7,GTF2IRD2,ZBED3,TRAF3IP2,KIAA1841,CRCP,RNPS1,HAS2,ZNF491,CYP27C1,GPR155,MBD1,CHST6,PEX2,C12orf49,SBF1,GALNT10,HSPA4L,SP2,GPRIN3,ZMAT3,CBX5,PARD3,ZNF708,TRIM16L,MPPE1" MicroRNA hsa-miR-548e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-12 2.02E-08 6.64E-12 6.11E-11 32 204 "ARMC12,NCOA1,KSR1,RUNX1T1,TBPL1,OSBPL3,PUM1,MYEF2,DPYSL2,DNAJB6,EIF1,KATNAL1,IQCG,IQGAP2,SESN1,TNRC6A,PCLO,CREG2,MAT2A,ZNF680,NFYA,GPR85,PSAT1,SDK2,CSRNP3,CPEB3,SOX3,ZHX3,SYPL1,AGTPBP1,TUBB2A,ZXDA" MicroRNA hsa-miR-216a-5p:TargetScan hsa-miR-216a-5p TargetScan 3.64E-12 2.04E-08 6.71E-12 6.17E-11 37 267 "CLK4,PTCHD1,NCOA1,DST,CDH2,L3MBTL4,PLAA,COL9A1,APPL1,PHF14,CTH,KLHL3,PDCD6IP,DTNA,FDFT1,ANKFY1,MSL3,PARD3B,PTPRT,HLF,HNF4G,JAK2,MITF,MMP16,MARCH1,NLGN1,CPEB4,EPC1,CXXC4,KDM3A,ERC1,ARHGAP26,CUX2,BHLHB9,CADM2,NAV3,RGS7BP" MicroRNA hsa-miR-6795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-12 2.08E-08 6.85E-12 6.30E-11 26 136 "HACE1,TRMT9B,PRX,ARHGDIA,BCL7A,CALM1,ZNF385A,PYGO1,ERBB2,MTHFD2,GCK,GFER,NXPH3,PLEC,ZNF426,SDK2,NCR3LG1,BDNF-AS,PRRT2,HSD11B1L,NMNAT2,NFASC,USP22,TUBB2A,RPRM,MGAT5B" MicroRNA hsa-miR-548aa:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-12 2.23E-08 7.34E-12 6.76E-11 30 181 "XKR4,SLC24A4,TNRC6C,ZNF385A,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,GPR85,PPP2R2B,NWD1,ROBO1,SALL1,TRA2B,BTBD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA hsa-miR-4270:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-12 2.24E-08 7.38E-12 6.79E-11 33 217 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ERBB2,SCML2,ZNF496,SLC6A17,COMMD5,NBL1,TBC1D25,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CLASP1,THRA,NACC2,PPIL6,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA hsa-miR-574-5p:PITA hsa-miR-574-5p:PITA_TOP PITA 4.12E-12 2.30E-08 7.57E-12 6.97E-11 23 106 "ATP1A1,ADGRB2,PTBP2,FOXN3,CNR1,NRN1,FOXO3,ZHX1,NEGR1,HSF2,MARK1,SEMA5B,CEP41,FNIP1,ARX,SLC4A3,SNAP25,SP4,RIMBP2,FLRT2,SH3GLB2,PRDM8,ADAMTS10" MicroRNA hsa-miR-1266:PITA hsa-miR-1266:PITA_TOP PITA 4.43E-12 2.48E-08 8.15E-12 7.50E-11 26 137 "KCNH8,LRFN2,CHRD,EIF4G3,CLTC,NCOR1,CLIP3,MATR3,EDNRA,PCOLCE2,AMOTL2,IP6K2,TTBK1,PTPRT,MBNL1,MSI1,NNAT,ZFHX4,PPP4R3A,FAM214B,ANKRD28,CAMTA1,PUM2,TIAM1,ERCC6L2,MEIS3" MicroRNA hsa-miR-6754-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-12 2.55E-08 8.38E-12 7.72E-11 33 218 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ERBB2,SCML2,ZNF496,SLC6A17,COMMD5,NBL1,TBC1D25,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CLASP1,THRA,NACC2,PPIL6,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA hsa-miR-4685-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.57E-12 2.55E-08 8.39E-12 7.72E-11 37 269 "XKR4,ADCY5,ADCY6,MTA3,AK2,SEMA4G,ARSE,BACH1,CCNT1,QKI,LRIG1,PITPNM3,PLCXD3,CYBB,SPATA2,EMX2,SLC43A2,SRRM4,ZNF638,BACH2,MIER3,SHISA6,KCNQ3,LSAMP,MBNL1,MYO5A,GPR137C,MTMR10,PTPRG,GTDC1,ATXN7,DIP2A,IQCE,RUNDC3B,TMEM198,RNF146,GAN" MicroRNA hsa-miR-1274a:PITA hsa-miR-1274a:PITA_TOP PITA 4.59E-12 2.57E-08 8.43E-12 7.76E-11 27 148 "MTMR3,CSNK1G3,NR1D2,EMX2,SCML2,PCDH17,FAM19A2,ADAMTS6,BACH2,MIER3,SMAP1,GPR62,KCNN2,NNAT,NOVA1,PRTG,CNNM2,TMEM260,PTPRD,ATP8B4,COPZ1,RGL1,TBL1X,SATB2,SLC44A1,UBE3A,TMEM237" MicroRNA hsa-miR-607:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.88E-12 2.73E-08 8.96E-12 8.25E-11 34 231 "CACNA1A,TMEM170A,YTHDC1,ANKRD46,TMTC1,YAF2,ZNF549,SCML2,IQCG,PDLIM5,TCERG1,TNRC6A,CIT,NACA,KSR2,PDE3A,FAM98B,SH3KBP1,PPARA,SH3TC2,SALL1,CSRNP3,ATF7IP,CPEB4,FAM126B,PEG10,PRRC2C,FAM208A,LRRC8A,RPL7L1,VLDLR,ZNF225,SLC38A1,PRDM10" MicroRNA hsa-miR-3148:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.08E-12 2.84E-08 9.31E-12 8.58E-11 35 244 "AXIN2,MTA3,ZBTB10,CALM1,CDC25B,HAPLN1,APPL1,LONRF1,SPATA2,PLEKHA1,TUBA1B,DLC1,TMEM164,MALT1,CRCP,GPR75,TNRC6A,PRUNE2,STMN1,ADAM22,PDE4D,PRRT2,SLC25A36,CPEB3,SLC6A8,SLC8A1,LIMCH1,NXT2,ZMAT3,NACC2,ZKSCAN5,LYPD6,SLC38A1,ITM2C,RTN4" MicroRNA hsa-miR-216b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.11E-12 2.86E-08 9.37E-12 8.63E-11 24 117 "ABCF1,TNRC6C,ATP2A2,JAZF1,CDH2,CRY2,IPCEF1,CENPL,SACS,SNX29,HSPA12B,HRASLS5,SEPT9,MXI1,NEXMIF,MTRF1L,ATAT1,GALNT10,GALNT17,ZNF610,UBE2H,UBTF,ZNF781,DHX33" MicroRNA hsa-miR-4441:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.19E-12 2.90E-08 9.51E-12 8.76E-11 33 219 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ERBB2,SCML2,ZNF496,SLC6A17,COMMD5,NBL1,TBC1D25,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CLASP1,THRA,NACC2,PPIL6,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA "GAGCCAG,MIR-149:MSigDB" "GAGCCAG,MIR-149:MSigDB" MSigDB 5.28E-12 2.95E-08 9.67E-12 8.90E-11 26 138 "ADD1,PCDH19,SEMA4G,ATP2A2,ADGRB1,SEC24C,RIMS4,LONRF1,KLHL3,BAIAP2,AMOTL2,AFF2,CBX1,KAT7,ICA1,GIT1,SLC11A2,NTRK3,ZMAT4,TNFRSF19,SLC6A8,IQSEC2,PHLDB1,TCF12,VLDLR,POLR3H" MicroRNA hsa-miR-4724-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-12 3.25E-08 1.06E-11 9.80E-11 22 98 "HFM1,ABCD2,CASK,ATP1B3,STX16,ZNF555,ABCG2,NRG2,PYGO1,SPATA2,YTHDC1,MAMLD1,DNAJB6,RASSF8,ZIC5,STMN1,ZNF680,PRKACB,MCMBP,GPRIN3,SLC35G2,ZNF17" MicroRNA hsa-miR-548au-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-12 3.25E-08 1.06E-11 9.80E-11 22 98 "RNF150,ATP1B3,ZNF582,ZMYM4,FOXN3,PITPNC1,ELMSAN1,APOPT1,MALT1,FICD,DDX19B,MKLN1,NWD1,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,TSN,TUBB2A,BCL2L13" MicroRNA hsa-miR-5193:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-12 3.45E-08 1.13E-11 1.04E-10 38 285 "PRX,DIS3L,IGLON5,RTTN,LRIG1,PDE4DIP,DBN1,RUSC2,TMCC2,RASA4,TMEM132C,CHST15,PCDH17,KIAA1958,SHISA6,NKD1,C2CD4C,KCNN1,KIFC3,CYP27C1,MAT2A,AFF1,EXOSC10,KANSL1,PIGG,PRRT2,KLHL11,PEX26,PKNOX2,BDP1,FAM208A,CRTC1,LAT2,AMZ1,DPYSL5,ZNF195,FAM13C,GAN" MicroRNA "AAAGGAT,MIR-501:MSigDB" "AAAGGAT,MIR-501:MSigDB" MSigDB 6.19E-12 3.47E-08 1.13E-11 1.04E-10 24 118 "PCDH19,SYNJ1,QKI,SLITRK5,ATP6V1H,GRB10,HAS2,KCND2,PIK3AP1,MEF2C,NFIX,PLXNB1,PPP2R5E,RDX,RET,ROBO2,SEPHS1,SOX11,NFASC,RGL1,CAMTA1,SATB2,CUX2,RPGRIP1L" MicroRNA hsa-miR-922:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-12 3.48E-08 1.14E-11 1.05E-10 28 161 "ELFN2,FZD9,TRMT9B,ZBTB10,ATP1B3,ZFP28,RUBCN,HEYL,GOLGA7,ATP13A4,FAM49B,MTHFD2,SRRM4,TNRC6A,RNFT2,IDH3A,MID1,KCTD15,KIAA0895L,COPZ1,CPEB3,CPEB4,AP4E1,WBP2,UBE2H,CCDC14,ZNF154,GDPD5" MicroRNA hsa-miR-4443:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-12 3.48E-08 1.14E-11 1.05E-10 23 108 "CASKIN1,NCOR2,CS,RASSF2,SGSM2,DOT1L,NEURL4,CSDC2,NEGR1,KLHL23,SAMD5,TMOD2,PLEC,POLG,SETD5,NCBP3,TRIM67,PEG10,ZSCAN29,SSBP2,TUBB2A,SMARCAD1,INTS3" MicroRNA hsa-miR-4438:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.22E-12 3.48E-08 1.14E-11 1.05E-10 41 326 "CLK4,ESYT2,MARCH3,ATP1B3,SLC2A11,ZMYM4,DIS3L,LETMD1,RNF14,SLC12A6,EIF4G2,TUBD1,SLC43A2,CEP78,FDFT1,SPECC1,TRAF3IP2,TXNL4A,ZNF491,NKD1,IL6R,METTL21A,CYP27C1,LAMP2,CHST6,ZNF426,MINDY2,SETD5,HSPA4L,FAM126B,SP2,ZNF621,PBLD,SYPL1,CBX5,PARD3,RPL7L1,CFAP298,ZNF70,SIGLEC10,AP3B2" MicroRNA hsa-miR-1299:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-12 3.51E-08 1.15E-11 1.06E-10 21 89 "BEND6,ATP1B3,DPY19L3,MYRF,CLCN3,TMEM184B,DCAF4,EPB41,CYP27C1,C1orf109,MYO18A,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,NACC2,TMPO,SSBP2,NDRG4,SLC30A4" MicroRNA hsa-miR-7111-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-12 3.62E-08 1.18E-11 1.09E-10 36 259 "RNF157,HACE1,SORCS2,TAOK1,PPFIA3,PRX,CAMK2A,METTL6,TMEM184B,CRMP1,PHC2,EIF4G1,AFF2,CELF1,PRRC2B,KCNH2,CHST6,NOVA2,CCSER2,PKM,DIRAS2,BDNF-AS,PRRT2,SETD5,EMID1,PKNOX2,FNBP1,ERC1,NFASC,USP22,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-99b:mirSVR_lowEffct hsa-miR-99b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.77E-12 3.79E-08 1.24E-11 1.14E-10 29 173 "ZFAT,CPNE5,ARNTL,BMPR1B,MTMR3,CA4,LURAP1,DBI,PLPPR4,NOP56,SESN1,ADAM28,INSM1,LSS,MYO7A,PURG,ING3,EPDR1,PTPRN2,FBXO11,SLC14A1,MYO16,KDM4C,TSPYL2,ST5,ANKRD28,DNMBP,UBE3A,VLDLR" MicroRNA hsa-miR-1296:mirSVR_highEffct hsa-miR-1296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.05E-12 3.94E-08 1.29E-11 1.19E-10 34 234 "BRAP,INTS2,MTUS1,CC2D2A,ZFYVE28,LRBA,STOML1,ZNF521,DCAF8,DPYSL2,ECM2,ANKRD46,RACK1,FGFR1,UFM1,ERGIC3,TUBGCP4,SLC2A6,AGBL5,MBNL1,BLOC1S2,NRCAM,TBC1D25,GNG2,USP47,RNASE1,PBRM1,GSTCD,SPIN3,RCOR3,SYN1,SYN2,RASD2,TPM1" MicroRNA hsa-miR-661:Functional MTI Functional MTI miRTarbase 7.45E-12 4.17E-08 1.36E-11 1.25E-10 50 459 "CLK4,SLC24A4,HACE1,TXNDC16,AQP6,ARHGDIA,ZNF555,SLC16A4,SUSD5,SOCS5,UBXN2A,GAPVD1,CENPL,RUSC2,KLHL3,SGSM2,MTX3,EIF5,MTSS1L,PCYOX1,ATP13A4,ANKFY1,TRMO,FUT9,CRCP,GPR75,NXPH3,DDX19B,KCNN3,CHST6,SLC11A2,TATDN3,STK32A,PEX2,CEP97,KLHL11,ZNF331,MCF2L2,SSTR2,ADAMTS17,PARD3,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,TBC1D15,TRIM16L,GAN" MicroRNA "AATGGAG,MIR-136:MSigDB" "AATGGAG,MIR-136:MSigDB" MSigDB 7.45E-12 4.17E-08 1.36E-11 1.25E-10 19 72 "USP37,JAZF1,KALRN,PLCXD3,CPEB2,PPARGC1A,ICA1,KCND1,SYTL4,NPR2,SNRK,PTPRG,RAD51D,RGS4,PBRM1,RADIL,KDM3A,SEPT3,RPGRIP1L" MicroRNA hsa-miR-4313:mirSVR_highEffct hsa-miR-4313:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.58E-12 4.24E-08 1.38E-11 1.27E-10 33 222 "CARNS1,DPP10,PHF12,PPP4R4,ZFYVE28,RNF182,LRRFIP1,AKAP6,APPL1,RIPOR2,LONRF1,DNM1,DUSP9,ABCC5,EGR3,SRRM1,F8,EFCAB2,NBEA,FREM1,MEIS1,VWA2,PTPRE,ENOX1,COPZ1,ZSWIM8,TSPYL2,POGZ,DIP2A,TACC1,CUX2,TIAM1,TLR4" MicroRNA hsa-miR-4473:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.82E-12 4.38E-08 1.43E-11 1.31E-10 17 56 "RNF157,ADD1,OSBPL8,PRC1,CLCN3,FEM1B,FLT1,MALT1,IL6ST,KCNB1,PURG,LRP12,CLIP1,SPART,ZMAT3,THRA,ZNF154" MicroRNA hsa-miR-3175:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.95E-12 4.45E-08 1.45E-11 1.34E-10 37 274 "CASKIN1,HACE1,TAOK1,PDZD4,ARRB1,ADGRB2,CBS,METTL6,ARHGEF2,RGS6,SEC16A,ABCC5,ING4,AMOTL2,AFF2,SRCAP,SHISA6,SOWAHA,PPM1L,MSI1,SAMD14,NBL1,GPR173,CCSER2,PLIN1,PTPRE,PRRT2,C12orf49,RPS6KA2,CLIP1,IQSEC2,CLSTN2,CAMTA2,SLC19A3,CBX5,UBTF,HNRNPA3" MicroRNA hsa-miR-153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.13E-12 4.55E-08 1.48E-11 1.37E-10 35 248 "MTA3,DDO,ZNF582,THSD7A,CBR1,CCNT1,CDH2,RTTN,TOGARAM2,UBXN2A,FEM1B,EPHB1,TAOK3,PDLIM5,ZNF274,COPS8,EID2B,RBPJ,KCNB1,MBNL1,SAMD5,PKM,SMIM7,CEP41,GDPD1,SNRK,ACSS3,RNASEL,EXD2,CARF,GSTCD,CCDC25,TRAPPC13,TROVE2,RICTOR" MicroRNA hsa-miR-99b*:mirSVR_highEffct hsa-miR-99b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-12 4.68E-08 1.53E-11 1.40E-10 25 130 "KCTD16,TTLL9,ARHGEF7,RUNX1T1,CREM,HS3ST2,MED12,MEX3B,EFCAB2,MSANTD4,OGA,ZNF276,TCERG1,NCKAP1L,SMAP1,KCNQ3,TMEM255A,RBBP6,ATXN7,CNKSR2,ZC3H4,TIAM1,TMPO,DCBLD1,PRTFDC1" MicroRNA hsa-miR-5089-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.69E-12 4.86E-08 1.58E-11 1.46E-10 44 372 "ZNF578,TAOK1,LDHD,PLAA,NRG2,CLOCK,CRY2,CSNK1E,PPP1R16B,UBXN2A,SLC12A6,IRAK4,TLR7,GTF2IRD2,FOXO3,TRAF3IP2,KIAA1841,TXNL4A,CRCP,ZDHHC15,METTL21A,CYP27C1,STMN1,GPR155,MBD1,CHST6,MINDY2,GALNT10,HSPA4L,PEX26,FAM126B,SP2,STAU1,ALG1,CLASP1,NSD1,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,MPPE1" MicroRNA hsa-miR-8064:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.80E-12 4.92E-08 1.60E-11 1.48E-10 26 141 "TNRC6C,CADPS,TBPL1,CRY2,IPCEF1,DNAL1,FGFR3,TRAF3IP2,PPARGC1A,FRMD3,BACH2,MBNL1,MPP2,GTDC1,ATAT1,STX1B,SCN8A,WDR37,UNC5B,SYT1,NACC2,BHLHB9,TPM1,UBE2H,UBTF,MFF" MicroRNA hsa-miR-3622b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.04E-12 5.06E-08 1.65E-11 1.52E-10 24 120 "SLC2A11,BACH1,CCNT1,CCPG1,SEC14L5,DNAH9,ABCC5,MRNIP,COQ7,SCML2,SEC24B,FOXO3,MSANTD4,CPLX2,RBPJ,MMP17,SFR1,PRKACB,MAPK9,ZFP30,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-610:PITA hsa-miR-610:PITA_TOP PITA 9.04E-12 5.06E-08 1.65E-11 1.52E-10 24 120 "SEMA4G,MTMR3,FAM19A5,COL4A5,DMD,EBF1,PLEKHA1,PAN3,SRRM1,CIT,ELOVL5,PTPRD,ROBO2,SGK1,PPM1E,BTBD3,SLC8A1,TET1,NKAIN2,STXBP1,NECAB1,ANKRD12,RGS7BP,HNRNPA3" MicroRNA hsa-miR-496.1:TargetScan hsa-miR-496.1 TargetScan 9.28E-12 5.19E-08 1.69E-11 1.56E-10 23 110 "ATP2A2,CD86,CDH2,MS4A7,ARHGEF6,PLCXD3,CALCRL,ANKFY1,PTPRT,MBNL1,SAMD5,NOVA1,PDE3A,LRP12,PRKACB,PTPRB,RFX3,CSRNP3,ELMO2,LIMCH1,HECW1,GPRIN3,FLRT2" MicroRNA hsa-miR-3124:mirSVR_lowEffct hsa-miR-3124:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.28E-12 5.19E-08 1.69E-11 1.56E-10 23 110 "ACTN1,KCTD16,CDC14B,MARK4,CARMIL3,CS,CSF1,SLC29A4,MBNL2,SLC37A3,DISC1,KDM2B,GRIK5,TOX2,KHK,PSAT1,GLDN,NUBPL,NKAIN2,MCF2L,MTCH1,CELF4,DNALI1" MicroRNA hsa-miR-939-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.36E-12 5.24E-08 1.70E-11 1.57E-10 31 199 "CASKIN1,AMPD2,ARMC12,ARRB1,CBS,TMEM184B,RGS6,ABCC5,ING4,AMOTL2,SRCAP,TNFAIP8L3,SHISA6,SOWAHA,KIF5A,MSI1,NBL1,GPR173,C12orf49,RPS6KA2,SH3BP2,ERC1,NFASC,CLSTN2,CAMTA2,SEPT8,SLC19A3,CBX5,RPRM,UBTF,HNRNPA3" MicroRNA hsa-miR-642a-5p:Functional MTI Functional MTI miRTarbase 9.73E-12 5.44E-08 1.77E-11 1.63E-10 33 224 "MTA3,ARRB1,STOML1,CRY2,RGS6,PITPNM3,UBXN2A,PLCXD3,MYADM,TMEM170A,RUSC2,HEYL,EMX2,ZNF391,FER,GPR75,GLUL,ZNF638,XRRA1,MYO5A,NEXMIF,KSR2,GLIPR1L2,PTPRG,GTDC1,GALNT10,WDR37,ZSCAN29,DOK6,KCNK12,SLC30A3,FRMD6,JPH3" MicroRNA hsa-miR-1262:PITA hsa-miR-1262:PITA_TOP PITA 9.99E-12 5.59E-08 1.82E-11 1.67E-10 25 131 "RTL9,SEMA4G,SYNJ1,NRXN3,DPH1,MBNL2,FGF13,MEX3B,AFF2,PCLO,GRIN2D,RNF165,HLF,MAT2A,NEXMIF,TCEAL5,ZNF827,PCSK1,PKIA,SNX22,SMPD3,TET1,USP1,ZIC1,NETO2" MicroRNA hsa-miR-493:PITA hsa-miR-493:PITA_TOP PITA 1.03E-11 5.76E-08 1.87E-11 1.72E-10 20 82 "RTL9,CADPS,ATP1B3,ADGRB3,SRSF11,SLC35F1,EIF4G2,TMEM35A,CPLX1,RAB30,TNRC6A,KDM2B,SOX21,NCKAP1L,IGF1,ZNF827,GNG2,SETD5,MCMBP,RCOR3" MicroRNA hsa-miR-6739-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-11 5.76E-08 1.87E-11 1.72E-10 20 82 "SPOP,ARHGDIA,INSYN2B,C1orf52,USP6NL,YTHDC1,YAF2,ERBB2,STAMBP,TNRC6A,ATOH8,NCKAP1L,IGF1,KSR2,PDE1B,DNAJC9,FAM200B,TNS1,TRPS1,UBE3A" MicroRNA hsa-miR-665:PITA hsa-miR-665:PITA_TOP PITA 1.03E-11 5.78E-08 1.87E-11 1.73E-10 32 212 "AMPH,OGT,CCAR2,SYNJ1,CACNA1G,RIMS4,TM9SF4,WDR20,DYNC1I1,RCAN2,EXTL2,CORO2B,FCGRT,AGAP3,EVL,GABRB3,PCDH17,TTBK1,GNAO1,IBA57,KCNB1,KCNN3,NNAT,PALM,GNG2,RASGEF1B,KIRREL1,SYN1,SMG6,DOK6,POLR3H,KAT6A" MicroRNA "TGAGATT,MIR-216:MSigDB" "TGAGATT,MIR-216:MSigDB" MSigDB 1.10E-11 6.17E-08 2.00E-11 1.84E-10 22 101 "NCOA1,DCLK1,MATR3,POM121,MBNL2,EGR3,MSL3,PTPRT,ADAMTS6,JAK2,MMP16,HNRNPM,GPR85,ANKRD16,PPM1B,CPEB4,KDM3A,SP4,ADGRL3,CUX2,RPGRIP1L,NETO1" MicroRNA hsa-miR-636:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-11 6.17E-08 2.00E-11 1.84E-10 22 101 "ELFN2,RNF157,SORCS2,OSBPL8,CCDC74A,DCAF4,FAM198B,SRRM4,HECTD2,LRP12,PRKACB,CNNM2,RAD51D,SLC25A36,ROBO1,GLDN,ZNF354C,SARS,SATB1,MPRIP,RPL7L1,HNRNPA3" MicroRNA hsa-miR-576-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-11 6.17E-08 2.00E-11 1.84E-10 22 101 "FZD9,ABCD2,PTBP2,CRY2,SUCO,ANKFY1,SARAF,GCK,ZHX1,HNF4G,NEGR1,IGF1,MBNL1,KITLG,NPTX2,PKM,FAM216A,TET1,AGTPBP1,RGMB,KAT6A,DPF3" MicroRNA hsa-miR-384:Non-Functional MTI Non-Functional MTI miRTarbase 1.10E-11 6.17E-08 2.00E-11 1.84E-10 22 101 "ADD2,GAS7,ATP1A1,RUNX1T1,LONRF2,CNN3,COQ7,MRVI1,SRRM4,FREM1,GPR155,NFIX,NTRK3,KANSL1,MARCH1,FBXW7,SCN2B,ZFP30,ST6GAL1,ZNF34,TRPS1,RICTOR" MicroRNA hsa-miR-224-5p:Functional MTI Functional MTI miRTarbase 1.19E-11 6.66E-08 2.16E-11 1.99E-10 25 132 "VXN,LONRF2,QKI,USP6NL,SEC14L5,DPYSL2,EDNRA,HIPK3,FEM1B,COQ7,RAB9B,ZNF585B,GORAB,TNRC6A,ADAP1,RASSF8,MITF,PTX3,C12orf49,RPL15,FRYL,ITGB3BP,TOM1L2,WRN,XPO1" MicroRNA hsa-miR-6507-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-11 6.66E-08 2.16E-11 1.99E-10 25 132 "HECW2,SEMA4G,ZBTB10,PRC1,ARHGEF4,MTX3,FAM107B,EIF4G2,ACSL4,FER,ZMAT1,MIER3,ZIC5,LIMS1,NCAM2,NELL2,SNX10,XRN1,ZNF426,PURG,SETD5,CSRNP3,SGK1,AGTPBP1,ACTR6" MicroRNA hsa-miR-708:PITA hsa-miR-708:PITA_TOP PITA 1.21E-11 6.76E-08 2.19E-11 2.01E-10 27 154 "PDZD4,AMPH,SEMA4G,CACNA1G,LDLRAD4,CABP7,DCLK1,CNTFR,SH2B1,GDA,GAPVD1,EPHB1,FOXO3,SYT3,CHL1,SESN1,MAT2A,NFE2L2,NNAT,TMEM260,RDX,SMARCC2,SPTB,SYN2,TRPS1,KAT6A,JMJD1C" MicroRNA hsa-miR-4719:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-11 6.76E-08 2.19E-11 2.01E-10 27 154 "BACH1,LIN54,CPEB2,PLXNC1,NEU3,KIAA1958,KAT7,USP51,MSI1,MYO6,NPTX1,CCSER2,PDZRN4,MAGEL2,HUNK,NCBP3,FNIP1,PPP4R3A,SLC12A2,PEG10,ZBTB43,NECAB1,DNAJC9,TAL1,LRRC8A,TUBB2A,HNRNPA3" MicroRNA hsa-miR-491-5p:TargetScan hsa-miR-491-5p TargetScan 1.23E-11 6.87E-08 2.22E-11 2.04E-10 26 143 "LRFN1,HAP1,P2RX6,CFL2,NRG2,C2CD2L,DMPK,HIPK3,APH1A,KAT8,KAT7,PADI2,MN1,NOVA2,PDE1B,NLE1,RORB,CSRNP3,FAM126B,KDM4B,FNBP1,PEG10,NFASC,ARHGAP9,RGMB,CLIP2" MicroRNA hsa-miR-412-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.23E-11 6.87E-08 2.22E-11 2.04E-10 26 143 "OSBPL8,CDH2,STOML1,SUSD5,DOCK4,GAPVD1,CENPL,NR1D2,STARD3NL,DLC1,CELF1,DOT1L,GUCY1A1,KPNA5,SYTL4,TMOD2,PKD1,SCN8A,CPEB4,ZC3H13,CYB561A3,CDH22,ZNF138,ZNF195,INTS3,TUBA1A" MicroRNA hsa-miR-3180-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-11 6.87E-08 2.22E-11 2.04E-10 26 143 "SEMA7A,APBB2,ZNF582,UBXN2A,RASGRP1,REEP2,CEP78,AFF2,CELF1,ZNF274,PARD3B,SLC6A17,XRRA1,ZNF827,ZNF426,MTRF1L,PRKCB,UBR7,SETD5,ELP2,RXRA,SGK1,CLSTN2,ANKRD28,URM1,NELFE" MicroRNA hsa-miR-411-5p.1:TargetScan hsa-miR-411-5p.1 TargetScan 1.24E-11 6.96E-08 2.25E-11 2.07E-10 21 92 "ADORA1,CACNB4,RUNX1T1,CCNT1,CDH2,AKAP5,PUM1,FBXL5,KLHL3,EIF4G2,ERBB4,CAMKK2,LNX1,LRP12,RORB,FNIP1,PREX2,EPC1,CLIP2,ELFN1,NAV3" MicroRNA hsa-miR-125b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-11 7.69E-08 2.48E-11 2.29E-10 23 112 "TXNDC16,TNRC6C,ZNF555,TOGARAM2,GREB1,TM9SF4,TMTC1,PLEKHA1,JKAMP,MSANTD4,SESN1,SYTL4,ZNF713,NDUFS7,GTDC1,SBF1,CSRNP3,POGZ,DIP2A,IQCE,USP22,NSD1,SLC38A1" MicroRNA hsa-miR-711:mirSVR_highEffct hsa-miR-711:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-11 8.57E-08 2.77E-11 2.55E-10 45 393 "KCNH8,AK2,ALK,LRCH2,FGD2,ZBTB10,TTLL9,LURAP1,CARS,LRBA,ARHGAP33,COL4A5,CNRIP1,ANKRD44,GPSM1,CYBB,DDX46,AASDH,LRRC17,FGF14,TMEM164,RAB30,ZNF638,PCLO,GRIA2,ZNF496,KCNN2,PIK3AP1,NOVA1,PPP2R2B,PIGG,CEP97,MORC4,ELP2,TCP11L1,CNKSR2,SNRPN,SYT1,CAMTA1,SYNPO2,AMACR,UGT8,ATP6V0E2,POLR3H,GDPD5" MicroRNA hsa-miR-193a-5p:PITA hsa-miR-193a-5p:PITA_TOP PITA 1.55E-11 8.68E-08 2.80E-11 2.58E-10 21 93 "KCNH8,PCDH19,RUNX1T1,DCLK1,ZMYM4,CNTNAP2,NR1D2,CPEB2,CELSR3,MAP2,MYO5A,NOVA1,ZNF827,PDE1C,OLA1,RELN,ZSCAN32,RBBP6,RGS4,MKRN3,LAMP5" MicroRNA hsa-miR-210-3p:Functional MTI Functional MTI miRTarbase 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "APC,CDK10,BTK,THSD7A,RUNX1T1,FOXN3,HECTD1,CSNK1E,GIT2,CPEB2,CASP8AP2,TBC1D16,AIFM3,CBX1,KCNB1,STMN1,MITF,NPTX1,PKIA,GTDC1,CHD9,CLASP2,MGRN1,HIF3A" MicroRNA hsa-miR-526a:PITA hsa-miR-526a:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "RALGAPA1,CLK4,NCOA1,ADGRB3,CALM1,NRXN3,AKAP6,DPP6,HIPK3,STAU2,TJAP1,CREG2,MN1,ZC3H12B,NRCAM,ROBO2,SNX22,NMNAT2,SS18,ANKRD28,RPGRIP1L,PUM2,TP53BP2,TRIM9" MicroRNA hsa-miR-519b-5p:PITA hsa-miR-519b-5p:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "RALGAPA1,CLK4,NCOA1,ADGRB3,CALM1,NRXN3,AKAP6,DPP6,HIPK3,STAU2,TJAP1,CREG2,MN1,ZC3H12B,NRCAM,ROBO2,SNX22,NMNAT2,SS18,ANKRD28,RPGRIP1L,PUM2,TP53BP2,TRIM9" MicroRNA hsa-miR-520c-5p:PITA hsa-miR-520c-5p:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "RALGAPA1,CLK4,NCOA1,ADGRB3,CALM1,NRXN3,AKAP6,DPP6,HIPK3,STAU2,TJAP1,CREG2,MN1,ZC3H12B,NRCAM,ROBO2,SNX22,NMNAT2,SS18,ANKRD28,RPGRIP1L,PUM2,TP53BP2,TRIM9" MicroRNA hsa-miR-519c-5p:PITA hsa-miR-519c-5p:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "RALGAPA1,CLK4,NCOA1,ADGRB3,CALM1,NRXN3,AKAP6,DPP6,HIPK3,STAU2,TJAP1,CREG2,MN1,ZC3H12B,NRCAM,ROBO2,SNX22,NMNAT2,SS18,ANKRD28,RPGRIP1L,PUM2,TP53BP2,TRIM9" MicroRNA hsa-miR-3622a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "SLC2A11,BACH1,CCNT1,CCPG1,SEC14L5,DNAH9,ABCC5,MRNIP,COQ7,SCML2,SEC24B,FOXO3,MSANTD4,CPLX2,RBPJ,MMP17,SFR1,PRKACB,MAPK9,ZFP30,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-1286:PITA hsa-miR-1286:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "GAS7,FAM131A,MARCH3,CFL2,QKI,SEC24C,DOCK4,TMEM132E,PCDH17,BACH2,CHIC1,MEF2C,NFIX,TRHDE,PRRT2,RORB,SCP2,CPEB3,FBXO11,WDR37,ZNF423,NFASC,ST5,WNK3" MicroRNA hsa-miR-518d-5p:PITA hsa-miR-518d-5p:PITA_TOP PITA 1.57E-11 8.79E-08 2.83E-11 2.61E-10 24 123 "RALGAPA1,CLK4,NCOA1,ADGRB3,CALM1,NRXN3,AKAP6,DPP6,HIPK3,STAU2,TJAP1,CREG2,MN1,ZC3H12B,NRCAM,ROBO2,SNX22,NMNAT2,SS18,ANKRD28,RPGRIP1L,PUM2,TP53BP2,TRIM9" MicroRNA hsa-miR-1234-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-11 9.23E-08 2.97E-11 2.74E-10 27 156 "ATP1B3,ZBED1,STOML1,ENTPD4,DNAL1,IRAK4,MRPL37,TLR7,APOPT1,FUT9,KIAA1841,SRCAP,TDRKH,HAS2,METTL21A,MBD1,PKD1,GDPD1,NWD1,DCUN1D2,SETD5,ZNF430,SP2,ZBTB43,KIAA0930,ZMAT3,ZNF610" MicroRNA hsa-miR-509-3p:PITA hsa-miR-509-3p:PITA_TOP PITA 1.67E-11 9.33E-08 3.00E-11 2.77E-10 22 103 "SYNJ1,MTMR3,CACNB4,CAMK2A,NR1D2,NRN1,TAOK3,GNAO1,GPD2,INSM1,LRRTM1,MAT2A,ENPP2,PKIA,PTPN13,USP47,RXRA,ATXN7,SCN2B,NECAB1,SMG6,CSMD1" MicroRNA hsa-miR-1304:PITA hsa-miR-1304:PITA_TOP PITA 1.68E-11 9.40E-08 3.02E-11 2.78E-10 25 134 "KIAA1324,OGT,SLC4A4,B4GALT6,CLIP3,SLC12A6,EPB41L2,BACH2,MEIS2,AFF1,ZC3H12B,CCSER2,SH3KBP1,WBP1L,USP47,SATB1,ATXN7,CPEB3,ZHX3,DICER1,NR2E1,TRPS1,TSC1,NAV3,MSRB3" MicroRNA hsa-miR-6773-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-11 9.52E-08 3.06E-11 2.82E-10 26 145 "TEX22,SFMBT2,DPY19L3,COL9A1,ZSCAN23,DBT,OPTN,TUBD1,TPPP,KAT7,MAP4,GPSM2,STRN3,PIGG,MTMR10,HSPA4L,BDP1,ERC1,SEPT3,KLHL7,KIAA0930,AP4E1,ZNF34,ZNF106,ZNF74,SLC38A1" MicroRNA hsa-miR-6892-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-11 1.01E-07 3.25E-11 2.99E-10 31 204 "ARRB1,ZBED1,STOML1,CRY2,RGS6,PITPNM3,UBXN2A,PLCXD3,CYBB,MYADM,TMEM170A,RUSC2,HIPK3,HEYL,EMX2,ZNF391,FER,GPR75,GLUL,ZNF638,SHISA6,C2CD4C,KSR2,PFKFB3,PTPRG,GALNT10,KCNK12,DPYSL5,SLC30A3,FRMD6,JPH3" MicroRNA hsa-miR-532-3p:PITA hsa-miR-532-3p:PITA_TOP PITA 1.92E-11 1.08E-07 3.46E-11 3.18E-10 27 157 "ADCY6,ALCAM,EIF4G3,CAMK2G,CDH2,HECTD1,CRY2,WDR20,DMTF1,PHC2,KMT5B,ETV1,PPARGC1A,ZIC5,PPM1L,NEXMIF,NFIX,NPTX1,PDE4D,IRX1,MAPK4,PSD,AMBRA1,NMNAT2,ANKRD12,EMSY,MSRB3" MicroRNA hsa-miR-7107-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-11 1.08E-07 3.46E-11 3.18E-10 27 157 "ATP1B3,ZBED1,STOML1,ENTPD4,DNAL1,IRAK4,MRPL37,TLR7,APOPT1,FUT9,KIAA1841,SRCAP,TDRKH,HAS2,METTL21A,MBD1,PKD1,GDPD1,NWD1,DCUN1D2,SETD5,ZNF430,SP2,ZBTB43,KIAA0930,ZMAT3,ZNF610" MicroRNA hsa-miR-6832-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-11 1.10E-07 3.53E-11 3.25E-10 36 269 "RNF157,CASKIN1,TAOK1,C6orf89,BACH1,AKAP6,BAG4,HINFP,SEC14L5,PYGO1,KIAA0586,WDPCP,C8orf37,ST6GALNAC3,TRAF3IP2,ZNF276,POLL,DDX19B,KPNA5,GPR155,LAYN,KSR2,MINDY2,GDPD1,ZIK1,ZNF793,NWD1,PRIMA1,ZNF621,ALG1,NSD1,GPRIN3,SSBP2,ZNF708,ZNF70,ZNF138" MicroRNA hsa-miR-597:PITA hsa-miR-597:PITA_TOP PITA 1.99E-11 1.11E-07 3.58E-11 3.29E-10 25 135 "ARHGAP20,NRXN3,QKI,RCHY1,PLCXD3,FOXO3,B4GALNT1,NEGR1,KCND2,LIFR,PTOV1,ZC3H12B,CNOT4,USP47,SEMA6D,SGK1,CPEB3,FHOD3,FAM126B,SOX11,SP4,PUM2,KAT6B,RPRM,TMEM237" MicroRNA hsa-miR-125a-3p:Functional MTI Functional MTI miRTarbase 1.99E-11 1.12E-07 3.58E-11 3.29E-10 39 310 "TMEM132B,TXNDC16,AK2,TAOK1,ARRB1,ARRB2,CFL2,STOML1,FAM131B,DPYSL2,IP6K2,FYN,GLUL,POLL,DDX19B,C2orf72,ZIC5,KCNN1,KCNN3,GIT1,P2RX7,TMOD2,PFKFB2,PIK3C2A,PIGG,NWD1,PRRT2,DCUN1D2,HUNK,HSPA4L,SGK1,ZNF430,ZBTB43,STAC2,TPM2,ZNF708,ZNF74,DPYSL5,FXR1" MicroRNA hsa-miR-423-3p:Functional MTI Functional MTI miRTarbase 2.02E-11 1.13E-07 3.62E-11 3.33E-10 33 230 "SFMBT2,KIF1A,LURAP1,ARHGEF2,SH2B1,APPL1,PUM1,LYPD1,DDX46,POM121,REEP2,SCML2,CEP78,ZFYVE27,NPTX2,SLC11A2,PKM,MAPK3,MRPS18A,SETD5,ROBO1,MCMBP,RXRA,ATXN7,SHMT2,ARFGAP1,LARP4,ZC3H4,SZT2,NACC2,TRPM2,TBC1D15,POLR3H" MicroRNA hsa-miR-504:PITA hsa-miR-504:PITA_TOP PITA 2.04E-11 1.14E-07 3.67E-11 3.38E-10 22 104 "ZNF608,CNTFR,RCHY1,ERC2,IP6K1,PLEKHA1,EPHB1,CHL1,PCDH17,PRRC2B,TMEM121B,ATXN2L,BACH2,NFIX,CNOT4,PDPK1,MINDY2,SMPD3,COPZ1,SNCA,LRRC8A,TSC1" MicroRNA hsa-miR-645:PITA hsa-miR-645:PITA_TOP PITA 2.10E-11 1.17E-07 3.77E-11 3.47E-10 20 85 "DPY19L3,SYNGR3,QKI,ZNF521,SEC24C,PUM1,GRB10,FRMD5,MIER3,GPR155,MEF2C,MITF,PPM1E,SEPHS1,SLC8A1,SOX11,ZSWIM8,HECW1,TCF12,XPO1" MicroRNA hsa-miR-214-3p:Functional MTI Functional MTI miRTarbase 2.33E-11 1.31E-07 4.19E-11 3.86E-10 31 206 "ELFN2,CASKIN1,SFMBT2,ZBTB10,LDLRAD4,QKI,TBPL1,CS,SOCS5,RUBCN,DAPK1,HEYL,ING4,FGFR1,SEMA4D,FAM49B,MTHFD2,GNAL,MEF2C,PPM1L,KCTD15,PLXNB1,CNNM2,ABLIM3,CPEB4,ERC1,DOCK9,TRPS1,RPL7L1,BCL2L13,GDPD5" MicroRNA hsa-miR-220b:PITA hsa-miR-220b:PITA_TOP PITA 2.35E-11 1.31E-07 4.20E-11 3.87E-10 26 147 "CAMK2G,LRBA,DCLK1,EGR3,TENM1,CHL1,KDM2B,KCND2,MARK1,GIT1,PDE4B,ANKRD16,PPP3CA,PKIA,C1orf109,CYB561D1,PPM1E,WDR47,MYO16,SOX11,ERBIN,ZC3H4,CLASP1,DOCK9,UBE3A,FXR1" MicroRNA hsa-miR-346:TargetScan hsa-miR-346 TargetScan 2.35E-11 1.31E-07 4.20E-11 3.87E-10 26 147 "PTCHD1,PDZD4,FAM131A,MTMR3,CACNA1I,NRG2,PPP1R16B,RIMS2,CCDC144A,LIN54,KLHL3,KIAA1958,PRRC2B,RNF165,C2orf72,NCOA7,MBNL1,MYO5A,PURG,RDX,CYB561D1,ATP8B4,ARHGEF40,PEG10,NACC2,PPIL6" MicroRNA hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA_TOP PITA 2.39E-11 1.34E-07 4.29E-11 3.95E-10 21 95 "PCDH19,MAP4K3,ADGRB1,PCYT1B,SEC24C,EGR3,GGT7,FAM19A2,ZIC5,KCND2,MGAT3,SCAMP5,NTRK3,FBXO11,TMCC1,ZHX3,SEPT3,TCF4,PUM2,RIMBP2,GAN" MicroRNA hsa-miR-382-3p:TargetScan hsa-miR-382-3p TargetScan 2.43E-11 1.36E-07 4.35E-11 4.00E-10 30 194 "PTCHD1,BEND6,OGT,APBB2,JAZF1,CA12,CCNT1,EGR3,KCTD3,FOXO3,FUT9,NFU1,GPR75,KCNN3,GPR155,HS6ST3,MXI1,MYO9A,NFYA,NOVA1,PAX6,PDPK1,RBBP6,NLGN1,CMTR2,FAM126B,LMO3,R3HDM1,NETO2,CPNE4" MicroRNA hsa-miR-3161:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-11 1.36E-07 4.36E-11 4.01E-10 23 115 "SPOP,GAS7,CBR1,QKI,UBXN2A,RASGRP1,EIF4G2,ZBED3,ELOVL5,MBNL1,PAX6,ENOX1,ZFHX4,SLC8A1,DIP2A,TPCN2,DOK6,NR2C2,TOM1L2,VLDLR,VSNL1,STOX2,NETO2" MicroRNA hsa-miR-889-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-11 1.40E-07 4.47E-11 4.12E-10 22 105 "FMNL2,MARCH3,ABCG2,UBXN2A,USP6NL,PYGO1,YTHDC1,CDON,KLHL5,KMT5B,SCML2,ZNF678,KCNN3,MKLN1,AFF1,HSPA4L,TCEA1,DOCK9,RGMB,TRPS1,SLC38A1,JMJD1C" MicroRNA hsa-miR-6860:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-11 1.41E-07 4.52E-11 4.16E-10 35 258 "SLC24A4,HACE1,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,CRCP,GPR75,DDX19B,MAP4,SLC11A2,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-1250-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-11 1.48E-07 4.74E-11 4.36E-10 31 207 "DDO,TMEFF1,CALM1,CBR1,CCNT1,C1orf52,TOGARAM2,APPL1,FEM1B,EPHB1,TBC1D16,TAOK3,SLC37A3,PDLIM5,ZNF274,COPS8,KCNB1,MSANTD3-TMEFF1,SMIM7,SPDL1,ACSS3,RNASEL,GSTCD,CCDC25,SALL1,NBPF1,TROVE2,ALG1,LRRC8A,ATP6V0E2,PRDM10" MicroRNA hsa-miR-513a-5p:Functional MTI Functional MTI miRTarbase 2.65E-11 1.48E-07 4.74E-11 4.36E-10 31 207 "ADD1,AK2,IGDCC4,ARNTL,CRY2,RGS6,LONRF1,LIN54,NR1D2,DUSP9,MAMLD1,GTF2IRD2,SUCO,CELF1,MIER3,SLC6A17,LIFR,MITF,MKLN1,HS6ST3,BDNF-AS,ALG9,SEMA6D,COPZ1,FNDC3A,ERC1,PEG10,ZNF106,ZBTB38,AP3B2,SPATA13" MicroRNA hsa-miR-1229-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-11 1.48E-07 4.74E-11 4.36E-10 31 207 "FMNL2,ZNF687,LRBA,LETMD1,TM9SF4,AIF1L,JAKMIP2,ABCC5,EIF4G2,EPB41L2,TUBA1B,MAD2L2,CELF1,NEU3,SRCAP,ACOT7,SCAMP5,MPP2,KCTD15,PBRM1,C12orf49,HUNK,SAFB,ERC1,SUPT5H,DNAJC9,RPGRIP1L,ZNF781,ZNF195,HNRNPA3,NETO2" MicroRNA hsa-miR-4537:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-11 1.50E-07 4.78E-11 4.40E-10 39 313 "HACE1,TXNDC16,TRMT9B,AQP6,ASPA,CBS,LETMD1,TMEM170A,MTX3,WDR20,MRO,MRNIP,EPB41,SCML2,CEP78,FECH,TRMO,ZNF44,DISC1,CRCP,GPR75,LILRA2,DDX19B,LAMP2,CHST6,MXI1,CCSER2,MTMR10,CEP97,TRIM68,PTGR2,ATAT1,LHPP,PBLD,USP22,PPIL6,SSBP2,LAT2,ZNF70" MicroRNA hsa-miR-328:PITA hsa-miR-328:PITA_TOP PITA 2.68E-11 1.50E-07 4.79E-11 4.41E-10 24 126 "ASIC1,USP37,HAP1,RUNX1T1,CABP1,SH2B1,FAM131B,DYNC1I1,MEX3B,ATXN2L,LRRC75A,KIF2A,MN1,ZC3H12B,CLDN11,PDE4B,SDK2,SNRK,GTDC1,FAM214B,SLC8A1,SOX11,ZNF423,PLCB1" MicroRNA hsa-miR-380-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-11 1.51E-07 4.82E-11 4.44E-10 19 77 "TNRC6C,CCDC74A,ANKRD44,FSD1L,EIF5,TUBD1,RAB9B,SCML2,MMADHC,SH3TC2,ALG9,PGBD4,FBXW7,SYPL1,TRPS1,ZFP37,FAM182B,HNRNPA3,NETO2" MicroRNA hsa-miR-1229:PITA hsa-miR-1229:PITA_TOP PITA 3.04E-11 1.70E-07 5.43E-11 5.00E-10 22 106 "APC,ATP2B2,RUNX1T1,EIF4G2,AFF2,GABRG2,GRIA2,RNF165,CELF5,MATN2,CNOT4,PDE4D,ZFHX4,RTN1,PPM1E,ZNF430,SLC12A2,SNCA,UBE3A,PRDM8,WNK3,SOCS4" MicroRNA hsa-miR-203b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-11 1.78E-07 5.68E-11 5.23E-10 28 172 "KIAA1211,PHF12,SEMA4G,SEC24C,SOCS5,GAPVD1,CRCP,KCNN3,CREG2,SLC11A2,TMOD2,PIGG,NCR3LG1,ERI2,FNIP1,HSPA4L,SH3BP2,NUBPL,PEX26,ANKRD36,ERC1,SSTR2,STAC2,KLHL7,SLC19A3,ZNF708,MPPE1,GAN" MicroRNA hsa-miR-874:PITA hsa-miR-874:PITA_TOP PITA 3.21E-11 1.80E-07 5.73E-11 5.28E-10 26 149 "XKR4,DYNLL1,CABP1,CNTNAP2,RHOBTB1,DTNB,EGR3,PPP1R1B,MEGF11,INPP5B,MAT2A,MXI1,NRCAM,PPP5C,OXR1,PPP4R3A,CPEB4,SPTB,ST5,ADGRL3,TBL1X,SATB2,THRA,NR2C2,TRPS1,MSRB3" MicroRNA hsa-miR-6766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-11 1.80E-07 5.75E-11 5.29E-10 34 247 "TAOK1,IGDCC4,BCL7A,CCNT1,ZNF445,CACNA2D2,ZNF385A,CSNK1E,IP6K1,E2F6,PLEKHA1,DOT1L,AHDC1,RNPS1,TNRC6A,PRRC2B,SOWAHA,KCNK3,MPP2,ZC3H12B,NFIX,PKM,PPARA,CEP97,PRRT2,SETD5,KLHDC8A,ATXN2,UNC5B,TPCN2,UBTF,ZNF708,SLC38A1,GAN" MicroRNA hsa-miR-4756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.28E-11 1.84E-07 5.85E-11 5.39E-10 25 138 "INTS2,BCAS1,CLDN10,PLAA,DNAH9,DNAJB6,TRMO,HHIPL1,CRCP,COPS8,TNRC6A,KIAA1958,KAT7,KIAA1755,IBA57,CREG2,PDPK1,NLE1,KANSL1,RNASEL,SGK1,ZFP30,PEX26,FAM126B,PDZD2" MicroRNA hsa-miR-1225-5p:PITA hsa-miR-1225-5p:PITA_TOP PITA 3.31E-11 1.85E-07 5.91E-11 5.44E-10 20 87 "KIAA1324,DOC2A,CDC14B,CERS5,KLHL3,DCTN4,ETV1,FGF11,SEMA4D,FAM49B,MEGF10,GABRB3,IQGAP2,L1CAM,ELOVL2,PTPRD,GTDC1,SEMA6D,ADAMTS17,TAL1" MicroRNA hsa-miR-4781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-11 1.91E-07 6.08E-11 5.60E-10 31 209 "TRMT9B,AKAP6,BAG4,CSNK1E,SEC14L5,KIAA0586,YTHDC1,TRMO,DOT1L,ZNF546,CREG2,CYP27C1,LAYN,MYO6,MINDY2,OXR1,SGSM1,NUBPL,PEX26,FAM126B,ZNF621,SSTR2,STAU1,ALG1,AGTPBP1,TMPO,SGK3,ZNF70,ZNF154,AP3B2,GAN" MicroRNA hsa-miR-8063:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.59E-11 2.01E-07 6.40E-11 5.90E-10 30 197 "XKR4,SPOP,CDC42BPA,DST,JAZF1,ZMYM4,CENPL,RCAN1,EDIL3,EDN3,FEM1B,DCTN4,CEP85L,AMOTL2,PRDM5,RNF165,HAS2,KIT,MAPT,CCSER2,ZNF426,SETD5,CNKSR2,BDP1,PEG10,DIP2A,NECAB1,TACC1,SLC19A3,SPATA13" MicroRNA hsa-miR-421:Functional MTI Functional MTI miRTarbase 3.63E-11 2.03E-07 6.46E-11 5.95E-10 33 235 "TNRC6C,ARHGAP22,RAB26,NSL1,RIMS4,E2F6,EIF4G2,DNAJC27,TUBA1B,MTHFD2,PPARGC1A,MSL3,KCNMB4,ATXN2L,NEGR1,IGF1,GAREM2,ZNF678,KCNN3,LIMS1,PAXBP1,NPTX1,PDPK1,POLG,FBXO11,TET1,TAF9,RGMB,TUBB2A,ZXDA,PARP11,ZNF30,SENP7" MicroRNA hsa-miR-219-1-3p:PITA hsa-miR-219-1-3p:PITA_TOP PITA 3.65E-11 2.04E-07 6.49E-11 5.98E-10 21 97 "ELFN2,JAZF1,DCLK1,NRXN3,ZNF385A,RHOBTB1,RNF165,ZHX1,KCNN3,KTN1,MBNL1,LRP1B,AFF1,NF1,NFYA,CNTN3,HECW1,ITPRID2,SS18,ARHGEF9,SYT1" MicroRNA hsa-miR-214-5p:TargetScan hsa-miR-214-5p TargetScan 3.86E-11 2.16E-07 6.88E-11 6.33E-10 25 139 "PWWP2A,HECW2,IGDCC4,MTMR3,HAP1,CFL2,ARMC8,CRY2,FAM169A,CNNM1,IQCG,EFCAB2,RAB30,KCNMB4,KIAA1755,MBNL1,AFF1,DBNL,NELL2,GPR173,CEP41,RORB,HSPA4L,CBX5,DPYSL5" MicroRNA hsa-miR-136-5p:TargetScan hsa-miR-136-5p TargetScan 3.91E-11 2.19E-07 6.96E-11 6.40E-10 35 262 "ELFN2,PWWP2A,KCTD16,DOCK11,ADAM23,DGKI,CCPG1,CACNA2D2,FHL5,OSBPL3,PLCXD3,ARHGEF4,KATNAL2,CPEB2,COPS4,MRVI1,AGAP2,PPARGC1A,CREG2,LIFR,NOVA2,PAX6,PLXNB1,RDX,RET,ERI2,RGS4,NUBPL,CPEB4,KDM3A,PEG10,MGRN1,RPGRIP1L,GDPD5,RGS7BP" MicroRNA hsa-miR-23a-3p:Functional MTI Functional MTI miRTarbase 4.03E-11 2.26E-07 7.17E-11 6.60E-10 34 249 "ZNF578,APAF1,ZBTB10,HIP1R,SOCS6,HAPLN1,DOCK4,TMEM170A,PDCD6IP,FSD1L,FOXO3,CELF1,MPP6,ADAM28,PPARGC1A,TXNL4A,TNRC6A,IL6R,MEF2C,PIK3R1,PKM,ZNF426,PPP2R5E,ZIK1,ACSS3,ATAT1,SEMA6D,FNIP1,PEX26,ERBIN,TSC1,RPL7L1,ZNF138,JMJD1C" MicroRNA hsa-miR-6818-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-11 2.28E-07 7.23E-11 6.66E-10 27 162 "SORCS2,SEMA6A,RUNX1T1,CCNT1,CLOCK,PPP1R16B,JAKMIP2,DMD,KATNAL1,FGF14,TRMO,CAMKK2,GLYR1,CBX1,SYNPO,KCNB1,IPO5,MITF,HS6ST3,OXTR,ZNF655,SH3TC2,SATB1,MGRN1,ZEB1,DOK6,VSNL1" MicroRNA hsa-miR-4271:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-11 2.28E-07 7.24E-11 6.67E-10 33 236 "TRMT9B,OGT,ARRB2,TPP1,ZNF385A,DUSP9,APH1A,MRO,GLUL,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,PFKFB2,PKM,FXYD1,EPB41L4B,WBP1L,IQSEC3,KIAA0895L,SBF1,COPZ1,SHMT2,PKNOX2,UNC5B,POGZ,MPRIP,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-744-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-11 2.28E-07 7.24E-11 6.67E-10 33 236 "AS3MT,TMEM132B,ESYT2,ISPD,AKAP5,CSNK1G3,SEC14L5,KIAA0408,KLHL5,MRNIP,COQ7,DLC1,GLUL,LILRA2,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,PEX26,FAM126B,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA hsa-miR-4421:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-11 2.36E-07 7.49E-11 6.90E-10 28 174 "SLC24A4,DPY19L3,CBS,CCNT1,ZNF445,PITPNM3,USP6NL,CENPL,TM9SF4,TMEM170A,C2CD2L,UFM1,SIGLEC8,POLL,MAP4,MEIS1,N6AMT1,SLC11A2,PALM,KLHDC8A,NCBP3,SCN2B,TRA2B,FAM208A,SZT2,PCDHA6,ZNF708,SIGLEC10" MicroRNA hsa-miR-5699-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-11 2.36E-07 7.49E-11 6.90E-10 28 174 "SLC24A4,DPY19L3,CBS,CCNT1,ZNF445,PITPNM3,USP6NL,CENPL,TM9SF4,TMEM170A,C2CD2L,UFM1,SIGLEC8,POLL,MAP4,MEIS1,N6AMT1,SLC11A2,PALM,KLHDC8A,NCBP3,SCN2B,TRA2B,FAM208A,SZT2,PCDHA6,ZNF708,SIGLEC10" MicroRNA hsa-miR-328-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.23E-11 2.37E-07 7.51E-11 6.91E-10 23 118 "CASKIN1,TXNDC16,TRMT9B,PHF12,PRX,ARHGDIA,BCL7A,CACNA2D2,ZNF385A,PYGO1,ERBB2,MTHFD2,GFER,CRCP,NFIX,PLEC,SDK2,HSD11B1L,NMNAT2,USP22,UBTF,MGAT5B,VGF" MicroRNA hsa-miR-3668:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-11 2.37E-07 7.52E-11 6.93E-10 18 70 "BACH1,SRSF11,CLCN3,ANKRD46,ZNF391,MTHFD2,SESN1,TNRC6A,ZNF678,MYO5A,PRKAB2,ZIK1,FIGN,PRIMA1,CSRNP3,CHD9,BTBD3,HNRNPA3" MicroRNA hsa-miR-3591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-11 2.51E-07 7.95E-11 7.32E-10 21 98 "USP37,CDC14B,CLCN3,CSNK1G3,ZC3H11A,CPEB2,DNAJB6,FARSB,GOLT1B,MSANTD4,FREM1,RAB30,MBNL1,PURG,ROBO1,TRA2B,SLC6A8,ZNF621,TROVE2,ZMAT3,ZXDA" MicroRNA hsa-miR-6079:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.50E-11 2.52E-07 7.99E-11 7.36E-10 24 129 "OGT,ATP1B3,PREPL,CNTNAP2,EPB41,ZNF391,ZNF585B,FOXO3,GCK,CYP46A1,CRCP,ZNF678,SGK1,R3HDM2,PEX26,ANKRD36,LIMCH1,SS18,TRIM2,SMUG1,BCL2L13,ZNF708,FBXO36,SPATA13" MicroRNA hsa-miR-6741-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.57E-11 2.56E-07 8.10E-11 7.46E-10 33 237 "XKR4,CDC14B,DIS3L,PCYT1B,HINFP,PITPNM3,KRBA2,HEYL,OPTN,EMX2,TUBD1,SLC43A2,FGFR1,APOPT1,MSANTD4,RAB40B,GPT2,DDX19B,SHISA6,IL6R,LIMS1,ZNF655,EXOSC10,APTX,MTMR10,NWD1,PNMA8A,SNX22,DIP2A,KLHL7,TPCN2,PCDHA6,ARL10" MicroRNA hsa-miR-503-5p:Functional MTI Functional MTI miRTarbase 5.03E-11 2.81E-07 8.92E-11 8.21E-10 34 251 "TAOK1,TRMT9B,CASK,DNAH17,MTMR3,CA8,CCNT1,LRWD1,CLTC,SOCS5,YTHDC1,ELMSAN1,SEC16A,DMTF1,PLEKHA1,MRPL10,FGFR1,MYO5A,OCRL,PIK3R1,PSAT1,CNNM2,PTPRD,ZFHX4,RPL15,FBXW7,KIAA0895L,SALL1,SBF1,KANK1,ZMAT3,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-5585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.16E-11 2.89E-07 9.14E-11 8.42E-10 20 89 "TAOK1,SLC4A4,ALDH7A1,FAM169A,PHF14,LONRF1,KMT5B,FER,DOT1L,PPARGC1A,LUZP2,RBPJ,SMAD9,KANSL1,FIGN,ATP8B4,SCN2B,RCOR3,SULF2,VSNL1" MicroRNA hsa-miR-548a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-11 2.95E-07 9.35E-11 8.61E-10 30 200 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154,IFT88" MicroRNA hsa-miR-548j-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-11 2.95E-07 9.35E-11 8.61E-10 30 200 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,TNS1,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-588:PITA hsa-miR-588:PITA_TOP PITA 5.33E-11 2.98E-07 9.44E-11 8.69E-10 25 141 "KCNH8,XKR4,USP37,CABP7,CNR1,ZC3H11A,DPH1,EMX2,GHR,TNRC6A,ADAMTS6,MAP2,GPR137C,PTPRO,FBXW7,SEMA6D,CCDC92,MYCBP2,CLSTN2,POGZ,LARP4,DMXL2,TRPS1,UBE2H,SLC17A7" MicroRNA hsa-miR-4776-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.43E-11 3.04E-07 9.61E-11 8.85E-10 22 109 "MARCH3,CD38,BAG4,PITPNM3,DBN1,EBF1,ZNF274,ZNF546,NTRK3,PDE3A,GDPD1,NWD1,RNASEL,SALL1,SCP2,SNAP25,TRPS1,VLDLR,ZNF28,ZNF138,PRDM10,FXR1" MicroRNA "ATAGGAA,MIR-202:MSigDB" "ATAGGAA,MIR-202:MSigDB" MSigDB 5.49E-11 3.07E-07 9.72E-11 8.95E-10 21 99 "ACTN1,CNN3,BAG4,KIAA0408,SNAP91,YAF2,PLEKHA1,SUCO,MEX3B,HLF,PPP5C,TTC13,KHDRBS2,ROBO2,SCN2B,CPEB3,CCDC88A,ERBIN,TCF12,SSBP2,STOX2" MicroRNA hsa-miR-503-5p:TargetScan hsa-miR-503-5p TargetScan 5.58E-11 3.12E-07 9.88E-11 9.09E-10 31 213 "ACHE,ARHGAP20,PPFIA3,CCAR2,CACNA1I,CAST,HECTD1,KLHL3,POM121,EIF4G1,RAB9B,GHR,NCKAP1L,C2orf72,NKD1,KIF5A,AQP11,MYO5A,NFYA,OCRL,PIK3C2A,PIK3R1,EPB41L4B,RASGEF1B,CNNM2,CYB561D1,HSPA4L,NMNAT2,CBX5,RICTOR,GAN" MicroRNA hsa-miR-362-5p:TargetScan hsa-miR-362-5p TargetScan 6.25E-11 3.50E-07 1.11E-10 1.02E-09 25 142 "ABR,DST,NRXN3,RIMS4,ERBB4,MRVI1,CORO2B,RAPGEF6,LOXL3,KCNN3,KIF2A,FAM216A,PLXNB1,EPDR1,PTPRD,GTDC1,HUNK,RMI1,CPEB4,PEG10,ADHFE1,ATMIN,FAM47E,HNRNPA3,GAN" MicroRNA hsa-miR-6858-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.31E-11 3.53E-07 1.12E-10 1.03E-09 24 131 "AK2,APBB2,CACNA1B,GAPVD1,SEC16A,EIF1,MRVI1,SYNCRIP,PDLIM5,PRRC2B,METTL21A,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,NMNAT2,PEG10,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-4716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-11 3.57E-07 1.13E-10 1.04E-09 28 177 "TRMT9B,SEPT7,AKAP6,CSNK1E,KIAA0408,KIAA0586,DBN1,CPEB2,WDPCP,TRMO,CELF1,ZNF274,CYP27C1,ADAM22,MYO6,TMOD2,NUBPL,PEX26,FAM126B,ZNF621,SSTR2,ALG1,AGTPBP1,SGK3,ZNF70,SLC38A1,MSRB3,GAN" MicroRNA hsa-miR-631:PITA hsa-miR-631:PITA_TOP PITA 6.72E-11 3.76E-07 1.19E-10 1.09E-09 21 100 "ADCY6,NCOA1,RUNX1T1,ZNF385A,ERC2,FAM131B,CNNM1,PSD2,LPAR4,RNF165,STMN1,MAT2A,MBNL1,ZC3H12B,AMBRA1,EPN2,SLC12A2,CLASP1,THRA,TMEM237,SMARCAD1" MicroRNA hsa-miR-548d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-11 3.80E-07 1.20E-10 1.10E-09 30 202 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,PPARA,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548i:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-11 3.80E-07 1.20E-10 1.10E-09 30 202 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,TTC13,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-4695-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.89E-11 3.86E-07 1.22E-10 1.12E-09 26 154 "PWWP2A,DOCK11,AKAP6,RTTN,HINFP,PYGO1,DRP2,KRBA2,HEYL,COQ7,IGSF6,GPR75,IL6R,GPR155,SAMD5,FITM2,MTMR10,PGBD4,SCN7A,HSPA4L,CXXC4,MYO16,SSTR2,DIP2A,ARL10,USP1" MicroRNA hsa-miR-4723-5p:Functional MTI Functional MTI miRTarbase 6.98E-11 3.90E-07 1.23E-10 1.13E-09 34 254 "RNF157,HACE1,SORCS2,TAOK1,PPFIA3,PRX,CAMK2A,METTL6,TMEM184B,CRMP1,EIF4G1,AFF2,CELF1,PRRC2B,KCNH2,CHST6,CCSER2,PKM,DIRAS2,BDNF-AS,PRRT2,SETD5,EMID1,PKNOX2,FNBP1,ERC1,NFASC,USP22,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-3185:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.24E-11 4.05E-07 1.28E-10 1.18E-09 27 166 "TRMT9B,NCOA1,ATP2A2,ARHGEF7,CLCN3,CNGA3,VCAN,CHRDL1,NR1D2,GLUL,NEGR1,ZIC5,NELL2,PFKFB3,MINDY2,MSANTD2,ALG9,ITPRID2,MPRIP,SATB2,HIF3A,SLC44A1,ARL10,WRN,PRDM10,ZDHHC20,FXR1" MicroRNA hsa-miR-1254:PITA hsa-miR-1254:PITA_TOP PITA 7.44E-11 4.17E-07 1.31E-10 1.21E-09 24 132 "PCDH19,ATP2B2,HAP1,CCPG1,AHCTF1,SLC35F1,IP6K1,TMEM35A,TOX3,SCAMP5,NOVA1,PKM,CLIP1,STX1B,SCN2B,MYO18A,HECW1,MTCL1,SATB2,ENHO,ZIC1,MEIS3,URM1,FZD3" MicroRNA hsa-miR-6864-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.62E-11 4.26E-07 1.34E-10 1.24E-09 39 324 "AS3MT,CC2D2A,TAOK1,TRMT9B,ISPD,CBS,TBRG4,LETMD1,RTTN,SOCS5,USP6NL,GAPVD1,MRO,EGR3,DCTN4,ZNF549,PCYOX1,SIGLEC8,KIAA1841,SRCAP,DDX19B,ZDHHC15,SCIN,IBA57,KCNN3,MBD1,CCSER2,SMIM7,STRN3,CNTLN,MTMR10,KLHL11,ZNF331,SEPHS1,ARHGAP26,ERBIN,VSNL1,LYPD6,PHTF2" MicroRNA hsa-miR-3672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.62E-11 4.26E-07 1.34E-10 1.24E-09 39 324 "AS3MT,CC2D2A,TAOK1,TRMT9B,ISPD,CBS,TBRG4,LETMD1,RTTN,SOCS5,USP6NL,GAPVD1,MRO,EGR3,DCTN4,ZNF549,PCYOX1,SIGLEC8,KIAA1841,SRCAP,DDX19B,ZDHHC15,SCIN,IBA57,KCNN3,MBD1,CCSER2,SMIM7,STRN3,CNTLN,MTMR10,KLHL11,ZNF331,SEPHS1,ARHGAP26,ERBIN,VSNL1,LYPD6,PHTF2" MicroRNA hsa-miR-3187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.77E-11 4.35E-07 1.37E-10 1.26E-09 34 255 "SLC24A4,HACE1,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,CRCP,GPR75,DDX19B,SLC11A2,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-4652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-11 4.42E-07 1.39E-10 1.28E-09 22 111 "SPOP,TNRC6C,SFMBT2,RASL11B,FOXN3,LRIG1,TMEM130,DPP6,DNAJB6,RASGRP1,EIF4G2,MRNIP,TAOK3,SYNCRIP,GRIK4,NCAM2,KSR2,GLIPR1L2,PDE3A,PKIA,BDP1,SLC38A1" MicroRNA hsa-miR-324-5p:TargetScan hsa-miR-324-5p TargetScan 7.89E-11 4.42E-07 1.39E-10 1.28E-09 22 111 "HECW2,PCDH19,CDC42BPA,LDLRAD4,CCNT1,PCYT1B,NRG2,DBN1,RCAN1,C3orf18,FYN,GGT7,FAM19A2,ARHGAP36,CHIC1,MGAT3,PTPRD,LGI2,FBXO11,NAPB,HNRNPA3,GAN" MicroRNA hsa-miR-4677-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.93E-11 4.44E-07 1.40E-10 1.29E-09 20 91 "SPOP,TNRC6C,C1orf52,USP6NL,YTHDC1,RCAN1,GOLT1B,YAF2,ERBB2,STAMBP,TNRC6A,ATOH8,NCKAP1L,XRRA1,NCAM2,PDE3A,PDE1B,SH3TC2,DNAJC9,TRPS1" MicroRNA hsa-miR-33a-5p:Functional MTI Functional MTI miRTarbase 8.38E-11 4.69E-07 1.47E-10 1.36E-09 28 179 "RNF157,KCTD16,OSBPL6,SEMA7A,ZNF583,CRY2,CSNK1G3,SOCS5,TMEM170A,EDN1,ACSL4,FER,VTI1B,MIER3,CNOT4,GPR137C,PSAT1,PPARA,PRKCB,ATF7IP,ZNF415,ERBIN,SATB2,LRRC8A,TNS1,RUNDC3B,REEP1,RTN4" MicroRNA hsa-miR-6870-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.65E-11 4.84E-07 1.52E-10 1.40E-09 34 256 "RNF157,HACE1,SORCS2,TAOK1,PPFIA3,PRX,CAMK2A,METTL6,TMEM184B,CRMP1,EIF4G1,AFF2,CELF1,PRRC2B,KCNH2,CHST6,CCSER2,PKM,DIRAS2,BDNF-AS,PRRT2,SETD5,EMID1,PKNOX2,FNBP1,ERC1,NFASC,USP22,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-559:Functional MTI Functional MTI miRTarbase 8.71E-11 4.88E-07 1.53E-10 1.41E-09 30 204 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,ERBB2,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-3663-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.03E-11 5.05E-07 1.59E-10 1.46E-09 31 217 "TMEM132B,NFS1,STOML1,TMEM184B,CSNK1G3,SEC14L5,MYADM,KIAA0586,RPS6KL1,ZNF461,CRCP,DDX19B,KCNN3,CYP27C1,MAN2A2,MYO5A,MYO6,SEPT4,POLR2F,DCUN1D2,KLHDC8A,SGSM1,NUBPL,ANKRD36,FAM126B,SSTR2,ZNF34,THRA,SGK3,ZNF70,DHX33" MicroRNA "ACACTCC,MIR-122A:MSigDB" "ACACTCC,MIR-122A:MSigDB" MSigDB 9.06E-11 5.07E-07 1.59E-10 1.47E-09 18 73 "ADGRB2,CDC42BPB,CS,CD320,GALC,TNRC6A,BACH2,NEGR1,MARK1,MEIS2,GIT1,NTRK2,ZNF827,MASP1,SLC4A3,FAM219A,DICER1,MICU3" MicroRNA hsa-miR-2276-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-11 5.18E-07 1.63E-10 1.50E-09 29 192 "MARCH4,ARRB1,STOML1,CRY2,RGS6,PITPNM3,UBXN2A,PLCXD3,MYADM,TMEM170A,RUSC2,HEYL,OPTN,EMX2,ZNF391,FER,MTHFD2,GPR75,GLUL,ZNF638,SHISA6,KSR2,PTPRG,GALNT10,THRA,KCNK12,SLC30A3,FRMD6,JPH3" MicroRNA hsa-miR-365:PITA hsa-miR-365:PITA_TOP PITA 9.60E-11 5.37E-07 1.69E-10 1.55E-09 27 168 "PTCHD1,SPOP,RGS20,ARRB2,DYNLL1,SYNJ1,SOCS5,DOCK4,HDAC4,TIAM2,EDNRA,ETV1,MEGF10,ADAMTS6,MARK1,MPP2,NFIX,TRHDE,POLG,SNRK,REV3L,KIRREL1,SGK1,WDR37,ANKRD28,SATB2,SGK3" MicroRNA hsa-miR-5189-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.63E-11 5.39E-07 1.69E-10 1.56E-09 34 257 "SLC24A4,HACE1,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,CRCP,GPR75,DDX19B,SLC11A2,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-5583-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.79E-11 5.48E-07 1.72E-10 1.58E-09 20 92 "ABCF1,ADD2,BRAP,BBOX1,CCNT1,DNAL1,YTHDC1,RASGRP1,KLHL5,MBNL2,BACH2,MBNL1,MKLN1,OLA1,PTPRD,ARL10,CSMD1,ZNF28,ZBTB38,SLC38A1" MicroRNA hsa-miR-379-5p:TargetScan hsa-miR-379-5p TargetScan 9.79E-11 5.48E-07 1.72E-10 1.58E-09 20 92 "HECW2,ARRB1,MTMR2,PITPNM3,JAKMIP2,EDN1,EIF4G2,KATNAL1,PCDH17,RAB30,CACFD1,FICD,KNDC1,KCTD6,FIGN,CYB561D1,KIAA0895L,PEG10,LGI4,MRPL47" MicroRNA hsa-miR-106b*:mirSVR_highEffct hsa-miR-106b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.96E-11 5.57E-07 1.75E-10 1.61E-09 21 102 "SYNJ2,FHL5,OSBPL3,FBXL5,IQCG,JKAMP,DOT1L,COPS8,TNRC6A,AP4S1,RNFT2,ZNF827,FAM218A,SH3GL3,PRRC2C,TCF4,SLC44A1,TIAM1,STOX2,TMEM178A,TRAM2-AS1" MicroRNA hsa-miR-605-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-10 5.77E-07 1.81E-10 1.67E-09 24 134 "TMCC3,RNF157,HECW2,ARRB1,CBFA2T2,AKAP5,FAM131B,PHC2,MTSS1L,MALT1,STARD3,ZNF496,IRAK3,NLE1,PMP22,TMEM104,SBF1,MAPKBP1,ZSCAN29,SATB2,USP22,ZNF106,ZNF74,URM1" MicroRNA hsa-miR-4530:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-10 5.77E-07 1.81E-10 1.67E-09 24 134 "SFMBT2,GPR146,LDLRAD4,NCOR2,CSNK1E,FAM131B,DMPK,FGFR1,FAM107A,RNFT2,MID1,PTCH1,PRRT2,ALG9,ATAT1,SALL1,ZFP30,MPRIP,ZNF34,WBP2,RPL7L1,BCL2L13,CCDC14,ZNF154" MicroRNA hsa-miR-1343-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-10 5.89E-07 1.84E-10 1.70E-09 29 193 "CASKIN1,ARMC12,ARRB1,CBS,TMEM184B,RGS6,ABCC5,ING4,AMOTL2,SRCAP,TNFAIP8L3,SHISA6,SOWAHA,KIF5A,MSI1,NBL1,GPR173,C12orf49,RPS6KA2,ERC1,NFASC,CLSTN2,CAMTA2,SEPT8,SLC19A3,CBX5,RPRM,UBTF,HNRNPA3" MicroRNA hsa-miR-612:Non-Functional MTI Non-Functional MTI miRTarbase 1.07E-10 5.99E-07 1.88E-10 1.73E-09 34 258 "SLC24A4,HACE1,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,CRCP,GPR75,DDX19B,SLC11A2,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-423-5p:TargetScan hsa-miR-423-5p TargetScan 1.07E-10 6.00E-07 1.88E-10 1.73E-09 26 157 "ACHE,PITPNM2,MARK4,AZGP1,NUMBL,RIMS4,KLHL3,ERBB2,PCYOX1,AGAP2,GLYR1,RNF165,KAT7,NFIX,NNAT,PDE1B,PKIA,BCAS3,GAL3ST4,AMBRA1,NMNAT2,MPRIP,PLCB1,CBX5,RPRM,KLC2" MicroRNA hsa-miR-6124:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-10 6.12E-07 1.91E-10 1.76E-09 28 181 "MTA3,CASKIN1,USP2,HAPLN1,CRY2,PYGO1,RAB39B,TUBA1B,AMOTL2,CELF1,MALT1,CRCP,TNRC6A,PRUNE2,GRIN2D,PACSIN2,ADAM22,SH3TC2,PRRT2,CPEB3,SLC6A8,SLC8A1,DIP2A,ZMAT3,ZKSCAN5,UBTF,LYPD6,SLC38A1" MicroRNA hsa-miR-6887-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-10 6.12E-07 1.91E-10 1.76E-09 28 181 "AK2,LRFN1,ARRB1,ASPA,GPR146,SH2B1,CYBB,KIF26A,SEPT9,FAM107A,PADI2,SHISA6,METTL21A,CYP27C1,VWA2,RDX,GTDC1,SETD5,ZFP1,ZHX3,NSFL1C,THRA,TNS1,RPRM,MGAT5B,ZNF24,URM1,PPP1R3F" MicroRNA hsa-miR-6746-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-10 6.23E-07 1.95E-10 1.79E-09 30 206 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,APAF1,CDC14B,SFMBT2,ADGRB2,IPCEF1,TMEM170A,DNAL1,MRNIP,VPS26C,ZNF585B,ZNF589,MTHFD2,BVES,NFIX,QDPR,ALG9,GSTCD,PTGR2,SEPHS1,ARC,ASTN2,FAM208A,CBX5,TBC1D15,ZNF28" MicroRNA hsa-miR-4638-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-10 6.25E-07 1.95E-10 1.80E-09 33 245 "CDC14B,DIS3L,HINFP,KRBA2,HEYL,OPTN,TUBD1,SLC43A2,MRPL37,FGFR1,APOPT1,MSANTD4,RAB40B,DDX19B,IL6R,LIMS1,ZNF655,EXOSC10,APTX,MTMR10,NWD1,PNMA8A,SNX22,PEX26,ZNF430,ERC1,ZBTB43,DIP2A,KLHL7,TPCN2,PCDHA6,GPR161,ARL10" MicroRNA hsa-miR-4725-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-10 6.39E-07 2.00E-10 1.84E-09 32 232 "TRMT9B,ARRB2,TPP1,ZNF385A,DUSP9,APH1A,MRO,GLUL,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,PFKFB2,PKM,FXYD1,EPB41L4B,WBP1L,IQSEC3,KIAA0895L,SBF1,COPZ1,SHMT2,PKNOX2,UNC5B,POGZ,MPRIP,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-6780b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-10 6.39E-07 2.00E-10 1.84E-09 32 232 "TRMT9B,ARRB2,TPP1,ZNF385A,DUSP9,APH1A,MRO,GLUL,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,PFKFB2,PKM,FXYD1,EPB41L4B,WBP1L,IQSEC3,KIAA0895L,SBF1,COPZ1,SHMT2,PKNOX2,UNC5B,POGZ,MPRIP,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-1285-3p:Functional MTI Functional MTI miRTarbase 1.19E-10 6.66E-07 2.08E-10 1.91E-09 34 259 "SLC24A4,HACE1,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,CRCP,GPR75,DDX19B,SLC11A2,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-409-5p:PITA hsa-miR-409-5p:PITA_TOP PITA 1.20E-10 6.74E-07 2.10E-10 1.94E-09 20 93 "KCTD16,OSBPL8,DPY19L3,SYNJ1,PUM1,DBT,KMT5B,RRAGB,STAU2,PPARGC1A,ADAMTS6,USP47,LGI2,FAM214B,RPGRIP1L,SLC44A1,TRPS1,VLDLR,KLC2,ZIC1" MicroRNA hsa-miR-4435:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-10 6.97E-07 2.18E-10 2.00E-09 33 246 "C6orf89,APAF1,ARHGDIA,AKAP6,LRIG1,CSNK1E,SOCS5,MYADM,KIAA0586,DBT,COQ7,TRMO,CRCP,DDX19B,ZNF678,CYP27C1,MPP2,MYO6,MINDY2,ZNF793,SGSM1,PTGR2,PEX26,FAM126B,UNC5B,LHPP,SSTR2,DIP2A,ALG1,AGTPBP1,WBP2,ZNF70,GAN" MicroRNA hsa-miR-877:PITA hsa-miR-877:PITA_TOP PITA 1.36E-10 7.62E-07 2.38E-10 2.19E-09 22 114 "PCDH19,AMPH,RCHY1,ERC2,TMCC2,FSD1L,STAMBP,OGA,MAP4K5,FRMD3,MN1,ZNF827,PTCH1,TTC13,REV3L,LMBRD1,SP4,NMNAT2,PEG10,PRRC2C,NAV3,PHTF2" MicroRNA hsa-miR-875-5p:PITA hsa-miR-875-5p:PITA_TOP PITA 1.36E-10 7.62E-07 2.38E-10 2.19E-09 22 114 "ESYT2,PPP4R4,CLOCK,TRIM69,CPEB2,EYA1,TAOK3,NEGR1,AQP11,PDE4D,RETREG1,SEMA6D,PPM1E,SP2,ITPRID2,SYPL1,TCF4,SATB2,TCF12,SYNE1,KAT6A,PHTF2" MicroRNA hsa-miR-3182:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-10 7.72E-07 2.41E-10 2.22E-09 19 84 "SPOP,TNRC6C,CASTOR3,AP1M1,CLCN3,RGS6,PLCXD3,RUSC2,SLC43A2,ZNF391,MRVI1,KCNN3,PDE3A,EPB41L4B,SEMA6D,FAM126B,BDP1,FAM208A,SZT2" MicroRNA hsa-miR-6756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-10 7.77E-07 2.42E-10 2.23E-09 33 247 "TAOK1,IGDCC4,BCL7A,CCNT1,ZNF445,CACNA2D2,ZNF385A,CSNK1E,IP6K1,PLEKHA1,DOT1L,AHDC1,RNPS1,TNRC6A,PRRC2B,SOWAHA,KCNK3,MPP2,ZC3H12B,NFIX,PKM,PPARA,CEP97,PRRT2,SETD5,KLHDC8A,ATXN2,UNC5B,TPCN2,UBTF,ZNF708,SLC38A1,GAN" MicroRNA hsa-miR-1909-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-10 7.96E-07 2.48E-10 2.28E-09 28 183 "ELFN2,RNF157,SEMA7A,HCN2,HEYL,IRAK4,DLC1,PDLIM5,CELF1,GFER,KCNK3,MSI1,PKD1,PLEC,SLC25A23,POLR2F,NCR3LG1,TMEM145,SARS,HES6,SP2,NFASC,MPRIP,CLASP1,ASXL3,GDPD5,ITM2C,HNRNPA3" MicroRNA hsa-miR-431*:mirSVR_highEffct hsa-miR-431*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-10 7.96E-07 2.48E-10 2.28E-09 28 183 "AP2A2,PKP4,SYNJ2,JAZF1,SMARCAL1,MYADM,TCAF1,INTS1,EGFR,VPS13B,FHL1,RGPD5,GABBR1,DIDO1,KHK,MMP16,P2RY13,NF1,APTX,RDX,EXD2,ARHGEF40,STXBP1,HEY1,ELP5,HIRA,SGK3,PRDM10" MicroRNA hsa-miR-6506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-10 8.05E-07 2.51E-10 2.31E-09 43 390 "ZNF578,TAOK1,LDHD,AP1M1,PLAA,CRY2,RGS6,CSNK1E,PPP1R16B,UBXN2A,DNAL1,SLC12A6,IRAK4,MRPL37,VPS26C,TLR7,GTF2IRD2,FOXO3,TRAF3IP2,MTHFD2,KIAA1841,TXNL4A,CRCP,POLL,BVES,ZDHHC15,NEGR1,CYP27C1,GPR155,MBD1,C12orf49,HSPA4L,PEX26,SP2,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,ZBTB38,MPPE1" MicroRNA hsa-miR-596:PITA hsa-miR-596:PITA_TOP PITA 1.48E-10 8.27E-07 2.57E-10 2.37E-09 20 94 "SEMA6A,JAZF1,CBARP,PHACTR3,ERC2,FBXL5,CHRDL1,DPYSL2,DTNB,EGR3,AGAP3,ELOVL5,NEGR1,MYLK2,FAM102A,SP4,TRIM9,CELF4,NAV3,ST8SIA2" MicroRNA hsa-miR-7641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-10 9.31E-07 2.90E-10 2.67E-09 24 137 "PWWP2A,TAOK1,DOCK11,AKAP6,RTTN,HINFP,SOCS5,PYGO1,DRP2,KRBA2,HEYL,COQ7,IGSF6,UFM1,IGF1,IL6R,MTMR10,SCN7A,HSPA4L,CHD9,DIP2A,ARL10,USP1,SLC30A4" MicroRNA hsa-miR-1292:mirSVR_highEffct hsa-miR-1292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-10 9.45E-07 2.94E-10 2.71E-09 23 126 "XKR4,STX16,DST,CHN2,NRXN3,CNTN1,PDE4DIP,PITPNC1,ZNF582-AS1,ADGRV1,TUBGCP4,LYRM9,NNAT,HYDIN,TMEM104,ERI2,SETD5,CPEB3,SLC11A1,SNRPN,MPRIP,TK2,ZNF23" MicroRNA hsa-miR-492:PITA hsa-miR-492:PITA_TOP PITA 1.72E-10 9.60E-07 2.99E-10 2.75E-09 19 85 "RALGAPA1,SEMA4G,NCOA1,ARHGEF4,DBN1,C2CD2L,RNF165,MAT2A,NPTX1,IGSF11,KCTD15,ROBO2,CSRNP3,TRA2B,CPEB3,SYN2,SLC44A1,THRA,SMARCAD1" MicroRNA hsa-miR-591:PITA hsa-miR-591:PITA_TOP PITA 1.77E-10 9.88E-07 3.07E-10 2.83E-09 21 105 "CASK,ATP2B2,MAP4K4,ZNF385A,DTNB,EGR3,ETV1,MEX3B,MEGF11,MIER3,NEGR1,INSM1,GPR85,EPB41L4B,MAPK10,SNRK,PPM1E,ERC1,TCF4,NSD1,TUBB2A" MicroRNA hsa-miR-3184-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-10 1.03E-06 3.21E-10 2.95E-09 28 185 "AK2,ARRB2,ARHGEF2,EVI5L,TMEM184B,SLITRK5,SPATA2,RPS6KL1,ABCC5,EIF1,BRSK1,SEPT9,AHDC1,POLL,PRRC2B,RNF165,KCNK3,MMP17,NFIX,PFKFB3,MTRF1L,SLC2A5,LIMS2,NFASC,SEPT8,NSD1,RPL7L1,URM1" MicroRNA hsa-miR-1257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-10 1.08E-06 3.37E-10 3.10E-09 22 116 "ABCD2,CDC14B,SPAG9,FOXN3,AKAP6,SLC35F1,EIF5,ZNF585B,ATP13A4,CRCP,LYPLAL1,ZNF844,GTDC1,ELP2,MCMBP,ZFP1,ZNF415,SPART,SYPL1,VSNL1,ZNF138,ZNF195" MicroRNA hsa-miR-3529-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-10 1.08E-06 3.37E-10 3.10E-09 22 116 "CDC14B,SPAG9,FAM169A,SPATA2,MTX3,RAB39B,DNAJB6,FCF1,FREM1,IBA57,ZNF678,MKLN1,NCAM2,FIGN,FBXW7,SEMA6D,HSPA4L,MPRIP,SYPL1,TPCN2,GORASP1,SPATA13" MicroRNA hsa-miR-3664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-10 1.10E-06 3.42E-10 3.14E-09 29 198 "TEX22,ESYT2,ZNF555,IGDCC3,GAPVD1,DBT,SGSM2,DCTN4,TUBD1,COQ7,ZNF549,KATNAL1,LILRA2,KAT7,NKD1,KLHL23,ZNF713,OLA1,BCAS3,PIGG,ELP2,NCBP3,HSPA4L,ANKRD36,DIP2A,ADAMTS17,ZNF106,WRN,RNF170" MicroRNA hsa-miR-498:Functional MTI Functional MTI miRTarbase 1.97E-10 1.10E-06 3.42E-10 3.14E-09 38 320 "AS3MT,RNF157,SLC4A4,CSNK1E,PLXNA4,CNNM1,MRNIP,RGS17,ERBB2,FDFT1,FOXO3,SLC37A3,CRCP,RNF165,ZNF491,NKD1,ITPKB,NCOA7,GPR155,MATN3,MID1,SAMD5,PCSK1,FAM216A,FITM2,ZNF844,NWD1,GALNT10,FNDC3A,PEX26,ZNF667,PCDHA6,DICER1,ZNF106,ASXL3,UBE2H,AGMO,ZXDA" MicroRNA hsa-miR-516a-5p:mirSVR_highEffct hsa-miR-516a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-10 1.17E-06 3.64E-10 3.35E-09 28 186 "XKR4,RGS9,ST3GAL5,WHRN,CPS1,VCAN,DDX46,SRRM1,STAU2,CRCP,GRIA2,FAM222A,ELOVL5,AGBL5,LRP1B,SRSF12,MXI1,NTRK3,EXOSC10,DCHS2,PTPRE,ZSCAN2,FIGN,ARMH4,FAM200B,ASXL3,METTL3,TSC1" MicroRNA hsa-miR-200a-3p:Functional MTI Functional MTI miRTarbase 2.11E-10 1.18E-06 3.67E-10 3.37E-09 25 150 "OGT,SPAG9,SEPT7,QKI,RASSF2,EGFR,DLC1,CELF1,MALT1,RAB30,IPO5,PCDH8,PTPRD,WDR37,ELMO2,ZNF621,TROVE2,ERBIN,SEPT8,ZEB1,DICER1,ZFPM2,ZMAT3,CLDND1,MFF" MicroRNA hsa-miR-367-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-10 1.22E-06 3.79E-10 3.49E-09 26 162 "ABCF1,AS3MT,ESYT2,ISPD,AKAP5,YAF2,MRNIP,COQ7,SYNCRIP,LILRA2,SCIN,IBA57,GPR155,MKLN1,ZNF713,PDE3A,OLA1,ELP2,RYR3,HSPA4L,ZFP30,PEX26,ANKRD36,FAM126B,ZNF154,RNF170" MicroRNA hsa-miR-487b:mirSVR_highEffct hsa-miR-487b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.19E-10 1.22E-06 3.79E-10 3.49E-09 26 162 "AMPH,MAP4K3,KALRN,NDST3,RAB28,NGEF,AKAP6,SNAP91,HS3ST2,DNM1L,GPHN,ARMCX1,GRIA2,DIDO1,SMAP1,ITPKB,ZNF655,PPM1B,RDX,RPS6KA2,CLIP1,BTBD7,SLC22A4,KAT6B,ZIC1,CADM2" MicroRNA hsa-miR-5580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-10 1.23E-06 3.80E-10 3.50E-09 15 51 "C6orf89,USP37,BACH1,ADGRB2,ARHGAP22,CSF1,RAB30,FICD,ADAM22,NFIX,NPTX1,MINDY2,ZNF793,PTGR2,ZNF708" MicroRNA hsa-miR-548ap-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548y:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548o-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548au-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ar-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548as-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548aq-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548am-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ak:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ad-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ay-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548bb-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-1301-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "ADD2,SEMA6A,DST,SYNJ2,CCNH,CHN1,NCOR1,CSNK1G3,YAF2,FAM13A,MRPL10,FECH,CELF1,TXNL4A,GLUL,KIAA1958,ATXN2L,MBNL1,ZNF680,NBL1,PKM,CPEB3,CDK5RAP2,TMPO,TP53BP2,WBP2,RUNDC3B,BCL2L13,POLR3H" MicroRNA hsa-miR-548h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548w:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ae-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ab:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 29 199 "PTCHD1,FAM135A,BACH1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,IL6ST,TM6SF1,MKLN1,PKD1,KLHL11,ALG9,CLIP1,TRA2B,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-145-5p:Functional MTI Functional MTI miRTarbase 2.22E-10 1.24E-06 3.83E-10 3.53E-09 32 238 "NDRG2,SMIM17,MYRF,THSD7A,CDH2,ZNF445,UBXN2A,NR1D2,APH1A,EGFR,ERBB4,EID2B,ZNF678,MEST,SAMD5,MYO5A,MYO6,ZNF426,PNMA3,PSAT1,PPP3CA,TUG1,UBR7,ALG9,ROBO2,CSRNP3,KIF21A,CPEB4,SOX11,CLSTN2,ANKRD28,MTMR14" MicroRNA hsa-miR-6879-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-10 1.27E-06 3.91E-10 3.60E-09 24 139 "LRFN1,RTTN,DBT,OPTN,TUBD1,COQ7,GPR75,KAT7,MAP4,GPSM2,STRN3,PIGG,MTMR10,PGBD4,HSPA4L,SLC22A4,ERC1,KLHL7,KIAA0930,ZNF34,ZNF106,ZNF781,ZNF74,TIGD6" MicroRNA hsa-miR-95-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-10 1.31E-06 4.04E-10 3.72E-09 23 128 "WDR35,TNRC6C,ARHGDIA,PTBP2,SPAG9,DGKB,YTHDC1,CPEB2,AASDH,SUCO,MMADHC,CRCP,GLI2,USP51,OCRL,P2RY1,TMEM200C,MRAS,LIMCH1,FAM126B,ZBTB43,RPL7L1,ZNF711" MicroRNA hsa-miR-4451:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-10 1.31E-06 4.04E-10 3.72E-09 23 128 "ZNF578,AQP6,SLC2A11,BACH1,DNAL1,MTX3,DNAH9,MAMLD1,EIF1,TUBD1,DISC1,POLL,TDRKH,DDX19B,SLC11A2,MTRF1L,GDPD1,QDPR,ARMH4,MAPKBP1,NSD1,TUBB2A,ZNF28" MicroRNA hsa-miR-8060:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-10 1.31E-06 4.04E-10 3.72E-09 18 77 "USP37,CA8,CCNT1,LONRF2,BAG4,CPS1,EDIL3,EDN1,TENM1,PLEKHA1,EIF1,NEURL4,LIFR,PEX2,SH3TC2,NBPF1,LGI3,TAF6" MicroRNA hsa-miR-3160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-10 1.31E-06 4.04E-10 3.72E-09 18 77 "ATP1A1,SH2B1,EMX2,AMOTL2,SRRM4,HMGCR,MAT2A,CCSER2,SNX10,FNDC3A,ZFP1,MPRIP,NACC2,RGMB,NEIL2,RICTOR,WNK2,ZDHHC20" MicroRNA hsa-miR-759:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-10 1.33E-06 4.10E-10 3.77E-09 28 187 "SLC24A4,KIAA1324,VXN,CCPG1,EPS15L1,SEC24C,FAM107B,E2F6,EDN1,C8orf37,RABEPK,ZNF549,KATNAL1,ATP13A4,ZNF234,GNAL,DDX19B,ZNF678,KCNN3,GPR137C,STK32A,SATB1,AMBRA1,FAM126B,TROVE2,AP4E1,AMACR,TUBB2A" MicroRNA hsa-miR-1231:PITA hsa-miR-1231:PITA_TOP PITA 2.44E-10 1.37E-06 4.20E-10 3.87E-09 25 151 "ACTN1,AMPH,JAZF1,NRXN3,QKI,GAPVD1,IP6K1,FGF14,PSIP1,SYNPO,MEIS2,GIT1,NEFM,NOVA1,NTRK2,QRICH1,HUNK,RCOR3,SOX11,SMG6,TIAM1,WIPF1,CELF4,MSRB3,SOCS4" MicroRNA hsa-miR-324-3p:PITA hsa-miR-324-3p:PITA_TOP PITA 2.48E-10 1.39E-06 4.27E-10 3.93E-09 27 175 "ADRA1B,LRFN1,FOXN3,ZNF385A,SH2B1,SEC24C,RIMS4,FAM131B,YTHDC1,C2CD2L,PHC2,RASGRP2,AGAP2,SRRM4,TNRC6A,SOWAHA,OLA1,PIK3R1,ZNF532,KIRREL1,SHC4,FAM214B,ERC1,CAMTA1,THRA,SPHK2,WNK2" MicroRNA hsa-miR-4517:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-10 1.43E-06 4.39E-10 4.04E-09 21 107 "ABCF1,ADD2,OSBPL3,YTHDC1,MTX3,RASGRP1,KLHL5,FRY,SCML2,FICD,BACH2,MKLN1,OLA1,CLIP1,CSMD1,TUBB2A,USP1,ZNF28,ZBTB38,ZFAND5,SLC38A1" MicroRNA hsa-miR-550:PITA hsa-miR-550:PITA_TOP PITA 2.56E-10 1.43E-06 4.39E-10 4.04E-09 21 107 "OSBPL8,CDK13,ADGRB1,AHCTF1,TM9SF4,YAF2,EGR3,EMX2,MRVI1,RAB30,ADAMTS6,IBA57,MAT2A,STRN3,PPP2R5E,RIPOR1,GTDC1,SOX11,LYPD6,DPYSL5,DPF3" MicroRNA hsa-miR-22-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.63E-10 1.47E-06 4.52E-10 4.16E-09 19 87 "TNRC6C,C1orf52,UBXN2A,YTHDC1,SEC16A,RCAN1,GOLT1B,YAF2,ERBB2,AFF2,STAMBP,NCKAP1L,XRRA1,NCAM2,PDE3A,PNMA3,SH3TC2,FAM208A,TNS1" MicroRNA hsa-miR-6728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-10 1.50E-06 4.61E-10 4.24E-09 20 97 "TBPL1,PITPNM3,KIAA0408,C2CD2L,SV2B,EDN3,FKTN,FGF1,UFM1,GSN,NKD1,NCOA7,PAX6,PLCL1,PKIA,SNAP25,GPRIN3,TSC1,UBE2H,UPF3A" MicroRNA hsa-miR-1307-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-10 1.55E-06 4.74E-10 4.36E-09 32 240 "CDC14B,DIS3L,ZNF385A,HINFP,KRBA2,HEYL,OPTN,TUBD1,SLC43A2,MRPL37,FGFR1,APOPT1,MSANTD4,RAB40B,DDX19B,IL6R,LIMS1,ZNF655,EXOSC10,APTX,MTMR10,PNMA8A,SNX22,PEX26,ZNF430,ERC1,ZBTB43,DIP2A,KLHL7,TPCN2,PCDHA6,GPR161" MicroRNA hsa-miR-29c-3p:Functional MTI Functional MTI miRTarbase 2.91E-10 1.63E-06 5.00E-10 4.60E-09 33 254 "TXNDC16,ZBTB10,NUMB,ELMSAN1,FEM1B,GOLGA7,DOT1L,MTHFD2,RAB30,BACH2,HMGCR,LIMS1,MYCN,ENPP2,KCTD15,PURG,PRKAB2,GTDC1,GLDN,SGK1,SEC31A,MAPKBP1,FAM126B,HECW1,CEP68,C12orf76,MMS19,DICER1,SIRT1,TIAM1,TUBB2A,ZNF45,TMEM237" MicroRNA hsa-miR-4448:Functional MTI Functional MTI miRTarbase 2.95E-10 1.65E-06 5.06E-10 4.65E-09 18 78 "RNF157,TBC1D14,ZBED1,TBPL1,CSNK1E,DNAJC27,AMOTL2,SRRM4,POLL,ZNF568,SLC6A8,CCDC88A,TRIM67,PDZD2,POGZ,SEPT8,PRRC2C,STXBP4" MicroRNA "GGGGCCC,MIR-296:MSigDB" "GGGGCCC,MIR-296:MSigDB" MSigDB 3.04E-10 1.70E-06 5.22E-10 4.80E-09 17 69 "UNC5A,PPFIA3,ARRB1,GPC2,LARGE1,NOG,NUMBL,CNTFR,DBN1,TAOK3,CPLX2,SOX21,KCTD17,SOX11,IQSEC2,TRPM2,SLC30A3" MicroRNA hsa-miR-6745:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-10 1.71E-06 5.25E-10 4.83E-09 28 189 "TAOK1,PDZD4,BCL7A,ZNF445,CSNK1E,GAPVD1,RASSF2,SGSM2,PLEKHA1,ZNF549,MRPL10,RNPS1,GNG4,GRIN2D,NFIX,PKM,PLCD1,PLEC,RETREG2,CEP97,PRRT2,SETD5,GALNT10,TPCN2,SSBP2,UBTF,SLC38A1,EVI5" MicroRNA hsa-miR-4743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-10 1.71E-06 5.25E-10 4.84E-09 21 108 "SFMBT2,RASL11B,FOXN3,LRIG1,PLCXD3,TMEM130,DPP6,DNAJB6,RASGRP1,EIF4G2,MRNIP,TAOK3,SYNCRIP,GRIK4,KSR2,GLIPR1L2,PDE3A,PKIA,BDP1,SZT2,SLC38A1" MicroRNA hsa-miR-4797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-10 1.81E-06 5.53E-10 5.09E-09 30 215 "ABCF1,SLC24A4,HACE1,KIAA1324,TBRG4,RTTN,DBT,DNAH9,DNAJB6,E2F6,TMEM35A,ZNF549,ZNF234,SRCAP,KAT7,DDX19B,ZDHHC15,SCIN,IBA57,KCNN3,MBD1,NFIX,MTMR10,STK32A,RDX,SATB1,TROVE2,AGTPBP1,SLC44A1,PPIL6" MicroRNA hsa-miR-411-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-10 1.81E-06 5.53E-10 5.09E-09 30 215 "TAOK1,ABCD2,C6orf89,WASF1,CDH2,AKAP6,HINFP,CSNK1E,KIAA0586,WDPCP,EIF4G2,PLEKHA1,C8orf37,TRAF3IP2,ZNF276,DDX19B,KPNA5,GPR155,MINDY2,ZNF793,NWD1,FAM161B,ZNF621,ATMIN,KIAA0930,TRIM2,GPRIN3,SSBP2,ZNF708,WNK3" MicroRNA hsa-miR-126-5p:Functional MTI Functional MTI miRTarbase 3.24E-10 1.81E-06 5.55E-10 5.11E-09 22 119 "SEMA7A,SRSF11,CSNK1G3,LIN54,SLC12A6,FOXO3,FYB1,GATM,GRIK5,IL6R,MYCN,NPTX1,SNX10,PSAT1,SETD5,CSRNP3,SMARCC2,MYCBP2,CBX5,NR2C2,UGT8,ZXDA" MicroRNA hsa-miR-4496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-10 1.81E-06 5.55E-10 5.11E-09 22 119 "AXIN2,NUMB,ABCG2,CRY2,SOCS5,SEC14L5,KIAA0408,HSPA12B,DLC1,CELF1,TVP23A,TJAP1,MKLN1,SEMA6D,LGI3,IQSEC2,DDN,NFASC,DIP2A,SYPL1,RTN4,SPATA13" MicroRNA hsa-miR-6742-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-10 1.82E-06 5.58E-10 5.13E-09 20 98 "TRMT9B,AMPD3,TMEM184B,PYGO1,IP6K1,ELN,RNPS1,IBA57,MAP4,NFIX,TBC1D25,PLEC,SLC25A23,SDK2,ATXN2,PEX26,PEG10,ARC,NACC2,UBTF" MicroRNA hsa-miR-7515:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-10 1.82E-06 5.58E-10 5.14E-09 25 153 "ELFN2,AK2,SEMA4G,ARRB2,HCN2,CA8,DUSP9,APH1A,ING4,PRRC2B,NXPH3,MIER3,IDH3A,MAT2A,SCAMP5,CLDN11,EPB41L4B,PRRT2,ANKRD36,SP2,STX1A,ARL10,TPM2,WBP2,URM1" MicroRNA hsa-miR-545-3p:Non-Functional MTI Non-Functional MTI miRTarbase 3.30E-10 1.85E-06 5.65E-10 5.20E-09 26 165 "DST,CSNK1G3,VCAN,UBXN2A,FAM13A,PLEKHA1,ANKMY1,MSANTD4,DISC1,NEGR1,DHX35,RBPJ,GPR137C,PSAT1,ZFHX4,SETD5,RPL15,PEX26,SYP,SYPL1,ZMAT3,MTMR14,TUBB2A,RPL7L1,NDRG4,FXR1" MicroRNA hsa-miR-6513-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.30E-10 1.85E-06 5.65E-10 5.20E-09 26 165 "AS3MT,TPP1,ENTPD4,ANKRD44,PDE4DIP,MYADM,ZBTB24,FKTN,ATP13A4,APOPT1,SRCAP,HAS2,EID2B,STMN1,MAN2A2,CHST6,ZNF426,NWD1,GSTCD,PGBD4,ANKRD36,ZC3H4,AGTPBP1,ZMAT3,ZNF34,SSBP2" MicroRNA hsa-miR-552:PITA hsa-miR-552:PITA_TOP PITA 3.47E-10 1.94E-06 5.93E-10 5.46E-09 28 190 "SPOP,SYNJ1,LDLRAD4,DGKI,DLGAP1,QKI,ZC3H11A,POM121,CELSR3,EMX2,MRVI1,USP21,PRRC2B,INPP5B,NEXMIF,NF1,NOVA1,NPTX1,MAPK10,SNRK,SGK1,FNDC3A,NLGN1,SYT1,CAMTA1,KIAA0930,TRPS1,VLDLR" MicroRNA hsa-miR-6807-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.48E-10 1.95E-06 5.95E-10 5.47E-09 54 577 "ABCF1,SYN3,CLK4,NDRG3,SLC24A4,HECW2,AK2,TAOK1,PHF12,ATP1B3,DOCK11,RGS11,CBFA2T2,CDR1,DIS3L,NRXN3,NCOR2,PPP1R16B,GAPVD1,DBT,MTX3,MRNIP,ZNF549,ANKMY1,KATNAL1,ZNF585B,CEP78,MSANTD4,COPS8,GPR75,GNG4,ZBTB49,DDX19B,ZNF491,NKD1,IL6R,INPP5B,CYP27C1,ZNF680,NFIX,TBC1D25,TMEM38A,TATDN3,MSANTD2,PGBD4,ATF7IP,FAM126B,SSTR2,TAL1,VWCE,ZNF70,EVI5,MPPE1,AP3B2" MicroRNA hsa-miR-769-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.56E-10 1.99E-06 6.08E-10 5.59E-09 31 229 "KIAA1211,BACH1,LRBA,LRWD1,TAOK2,USP6NL,LONRF1,INTS1,MRO,PLEKHA1,SCML2,SCARA3,FAM49B,KIAA1841,TCERG1,PRUNE2,ZNF678,NELL2,ZDHHC8,PKM,PEX2,CEP97,KLHL11,ZC3H14,SCP2,PEX26,FAM126B,ZSCAN29,SLC37A2,RGMB,SPIRE1" MicroRNA hsa-miR-134-5p:TargetScan hsa-miR-134-5p TargetScan 3.58E-10 2.00E-06 6.11E-10 5.63E-09 24 142 "ELFN2,EPB41L5,CDK13,CDR1,CPS1,RIMS2,JAKMIP2,CDON,DRP2,PLXNC1,CEP85L,MRVI1,MTHFD2,GNAO1,KAT7,HAS2,HNMT,IDH3A,MAT2A,MBNL1,CEP41,IQSEC2,ADAMTS17,KCNK12" MicroRNA "ATGCTGG,MIR-338:MSigDB" "ATGCTGG,MIR-338:MSigDB" MSigDB 3.67E-10 2.05E-06 6.26E-10 5.76E-09 21 109 "ESYT2,SEMA6A,MAP4K3,ZBTB10,N4BP2L1,FRY,KCND2,MYCN,NOVA1,SEPT4,TMEM255A,ZFHX4,FBXW7,SEMA6D,CPEB3,MYCBP2,CLASP2,LARP4,SYN2,AP4E1,TBC1D15" MicroRNA hsa-miR-611:mirSVR_highEffct hsa-miR-611:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.69E-10 2.06E-06 6.29E-10 5.79E-09 18 79 "CARMIL3,DNM1L,APH1A,CLVS1,CELF1,STARD3,ELOVL5,SMAP1,PCSK5,NLGN3,MTRF1L,TTC13,GTDC1,MTCL1,RIMBP2,C9orf85,TRPS1,OSBP2" MicroRNA hsa-miR-518b:mirSVR_highEffct hsa-miR-518b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.78E-10 2.12E-06 6.45E-10 5.94E-09 26 166 "LRFN2,ZNF608,CFAP410,PPT2,SMARCAL1,SOCS5,ACSL4,FGFR1,FHL1,SYT17,CCDC184,ZHX1,MEIS2,KITLG,ZC3H12B,ZNF827,TMEM255A,RBBP8,ZDHHC14,FBXO11,MCF2L,NSD1,TSN,PLEKHH2,KCNK12,PARP11" MicroRNA "ACAGGGT,MIR-10A:MSigDB" "ACAGGGT,MIR-10A:MSigDB" MSigDB 3.84E-10 2.15E-06 6.54E-10 6.02E-09 22 120 "ZNF608,KCTD16,DOCK11,NRP2,MTMR3,CAMK2G,NCOR2,FLT1,ANKFY1,TMEM121B,RNF165,BACH2,SMAP1,NFIX,PURG,FIGN,KCTD17,MAPKBP1,NFASC,TRIM2,CSMD1,WNK3" MicroRNA "ACAGGGT,MIR-10B:MSigDB" "ACAGGGT,MIR-10B:MSigDB" MSigDB 3.84E-10 2.15E-06 6.54E-10 6.02E-09 22 120 "ZNF608,KCTD16,DOCK11,NRP2,MTMR3,CAMK2G,NCOR2,FLT1,ANKFY1,TMEM121B,RNF165,BACH2,SMAP1,NFIX,PURG,FIGN,KCTD17,MAPKBP1,NFASC,TRIM2,CSMD1,WNK3" MicroRNA hsa-miR-4280:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-10 2.17E-06 6.62E-10 6.09E-09 17 70 "USP37,ARNTL,BACH1,EVI5L,HECTD1,CSNK1G3,UBXN2A,GAPVD1,DNAJB6,EIF5,SCML2,KAT7,PEX26,SP4,TROVE2,VLDLR,ZNF24" MicroRNA hsa-miR-617:PITA hsa-miR-617:PITA_TOP PITA 3.94E-10 2.21E-06 6.72E-10 6.19E-09 20 99 "SYN3,SOCS6,SOCS5,PLCXD3,NCALD,CHL1,ERAP1,TCERG1,RAB30,ZC3H12B,PIK3R1,RETREG2,EPB41L4B,PDZD2,SOX11,CDK19,STXBP1,ZNF106,TIAM1,SLC38A1" MicroRNA hsa-miR-6500-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-10 2.27E-06 6.91E-10 6.36E-09 30 217 "AS3MT,BRAP,HACE1,SFMBT2,ZNF583,ISPD,FOXN3,SUSD5,USP6NL,SGSM2,CELSR3,MRNIP,SEPT9,GPR75,ADAP1,KAT7,SLC11A2,CCSER2,BDNF-AS,ZNF844,CEP97,SLC25A36,MYO18A,KANSL3,CDK19,PCDHA6,GALNT17,BHLHB9,EVI5,JMJD1C" MicroRNA hsa-miR-521:mirSVR_highEffct hsa-miR-521:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.18E-10 2.34E-06 7.11E-10 6.55E-09 27 179 "KDM5D,PDE8B,ZSCAN18,DST,TPP1,PREPL,PDE4DIP,KIAA0753,EBF1,PLEKHA1,ARMCX1,TMEM107,DOT1L,OGA,GALNT15,NEU3,ARFIP1,TNRC6A,GPD2,FAM222A,HLF,MYT1,NF1,MAST1,CLASP2,CSMD1,NETO1" MicroRNA hsa-miR-4472:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-10 2.34E-06 7.11E-10 6.55E-09 27 179 "TRMT9B,AMPD3,BCL7A,CAMK2A,CBARP,TMEM184B,ZNF385A,PYGO1,MRNIP,ELN,DOT1L,MTHFD2,GFER,PRRC2B,TJAP1,MAP4,PKM,NLE1,PLEC,SMOX,SLC25A23,SDK2,ATXN2,PKNOX2,PEG10,NACC2,RICTOR" MicroRNA hsa-miR-4447:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-10 2.34E-06 7.11E-10 6.55E-09 27 179 "TRMT9B,AMPD3,BCL7A,CAMK2A,CBARP,TMEM184B,ZNF385A,PYGO1,MRNIP,ELN,DOT1L,MTHFD2,GFER,PRRC2B,TJAP1,MAP4,PKM,NLE1,PLEC,SMOX,SLC25A23,SDK2,ATXN2,PKNOX2,PEG10,NACC2,RICTOR" MicroRNA hsa-miR-122-5p:TargetScan hsa-miR-122-5p TargetScan 4.32E-10 2.42E-06 7.35E-10 6.77E-09 26 167 "NDRG3,CDC42BPB,CRY2,CS,ARHGAP32,ERBB4,CD320,FGF1,FOXO3,ATP6V1H,IGSF5,BACH2,NEGR1,MBNL1,MEIS2,GIT1,MYO9A,PKM,MASP1,PTPRB,SATB1,PEG10,HIF3A,DICER1,MICU3,CADM2" MicroRNA hsa-miR-549:PITA hsa-miR-549:PITA_TOP PITA 4.32E-10 2.42E-06 7.35E-10 6.77E-09 26 167 "USP31,PCDH19,GAS7,ZBTB10,LDLRAD4,ERC2,DMTF1,PDCD6IP,PAN3,SOX21,MIER3,LIFR,MARK1,MYO5A,FBXW7,CASC3,SCAF8,SGK1,CPEB3,CHD9,SOX11,SP4,PEG10,POGZ,SMARCAD1,HNRNPA3" MicroRNA hsa-miR-5088-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-10 2.42E-06 7.35E-10 6.77E-09 26 167 "SORCS2,SPOP,LURAP1,CAMK2G,NUMBL,LRIG1,PLCXD3,FEM1B,TMTC1,AMOTL2,GPD1,PADI2,EID2B,MYO5A,NPTX2,GPR137C,PDE1B,KANSL1,DPF2,TMLHE,ELP2,VWCE,RUNDC3B,TMEM198,DPF3,RNF146" MicroRNA hsa-miR-1267:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.33E-10 2.42E-06 7.35E-10 6.77E-09 25 155 "ABCF1,AS3MT,ESYT2,ISPD,AKAP5,MRNIP,COQ7,SYNCRIP,LILRA2,SCIN,IBA57,GPR155,MKLN1,ZNF713,PDE3A,OLA1,ELP2,HSPA4L,ZFP30,PEX26,CPEB4,ANKRD36,ERC1,ZNF154,RNF170" MicroRNA hsa-miR-503:mirSVR_highEffct hsa-miR-503:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.33E-10 2.42E-06 7.35E-10 6.77E-09 25 155 "ACHE,MARK4,KSR1,DCAF8,E2F5,TSPAN5,FCGR1A,STRADA,SDCBP2,RNF165,FRMD3,PAXBP1,MSR1,MYO7A,NDP,RBBP6,SEC14L1,KIF21A,ZNF423,DBNDD2,SEPT3,TPM1,RICTOR,MKRN3,TTC7A" MicroRNA hsa-miR-1973:mirSVR_highEffct hsa-miR-1973:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-10 2.45E-06 7.43E-10 6.84E-09 21 110 "SLC24A4,BCAS1,BARD1,LRRFIP1,VCAN,DAPK3,USP3,MBNL2,FLNC,GLI2,GPD2,TNFAIP8L3,MEIS2,MIA2,LAYN,PCDH9,EPDR1,LRRK2,SHC4,CDH22,TMEM198" MicroRNA hsa-miR-302d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-10 2.45E-06 7.43E-10 6.84E-09 21 110 "USP37,TMEFF1,CLOCK,MYADM,SCRN1,SPATA2,JAKMIP2,TBC1D16,FGF1,AMOTL2,GPR75,TNRC6A,FAM69A,MSANTD3-TMEFF1,LSAMP,OLA1,ZNF793,FNDC3A,BTBD7,EML6,DHX33" MicroRNA hsa-miR-764:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.39E-10 2.45E-06 7.45E-10 6.86E-09 33 258 "TMEM132B,TAOK1,ARRB1,STOML1,FAM131B,YTHDC1,POLL,DDX19B,C2orf72,ZIC5,KCNN1,KCNN3,P2RX7,GPR137C,TMOD2,PIK3C2A,PKM,PIGG,NWD1,PRRT2,DCUN1D2,KLHDC8A,HUNK,HSPA4L,ZNF430,INAVA,ZBTB43,ZNF621,STAC2,CYB561A3,ZNF708,FXR1,AP3B2" MicroRNA hsa-miR-363-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-10 2.48E-06 7.53E-10 6.93E-09 28 192 "TAOK1,PDZD4,BCL7A,ZNF445,CSNK1E,GAPVD1,RASSF2,SGSM2,PLEKHA1,ZNF549,MRPL10,RNPS1,GNG4,GRIN2D,NFIX,PKM,PLCD1,PLEC,RETREG2,CEP97,PRRT2,SETD5,GALNT10,TPCN2,SSBP2,UBTF,SLC38A1,EVI5" MicroRNA hsa-miR-635:PITA hsa-miR-635:PITA_TOP PITA 4.76E-10 2.66E-06 8.08E-10 7.44E-09 20 100 "PPFIA3,RCBTB2,FOXN3,QKI,PCYT1B,ZNF385A,FAM131B,KLHL3,APH1A,RRAGB,BRSK1,PIK3R1,PPP3CA,SGSM1,RTN1,SOX11,PEG10,NKAIN2,SYT1,MAP3K12" MicroRNA "ACTGCAG,MIR-17-3P:MSigDB" "ACTGCAG,MIR-17-3P:MSigDB" MSigDB 4.76E-10 2.66E-06 8.08E-10 7.44E-09 20 100 "SORCS2,OGT,ARMC8,TM9SF4,EIF4G1,OLFM1,KAT7,MAP4,MEIS1,RTL5,CNOT4,NTRK2,KANSL1,NKAIN1,GTDC1,ZFHX4,USP33,SOX11,ZNF423,FSTL5" MicroRNA hsa-miR-28-3p:PITA hsa-miR-28-3p:PITA_TOP PITA 4.94E-10 2.76E-06 8.38E-10 7.71E-09 26 168 "ZNF608,PPP4R4,TAOK2,AHCTF1,LONRF1,ACSL4,FOXO3,RNF165,ELOVL5,HMGCR,SMAP1,NFIX,GPR85,CCSER2,USP47,SEMA6D,FNDC3A,ST6GAL1,CNKSR2,SNAP25,CDK19,SS18,STAU1,TRIM2,AKTIP,TSC1" MicroRNA hsa-miR-1470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.01E-10 2.80E-06 8.49E-10 7.82E-09 28 193 "ARRB1,ARSE,TOGARAM2,PLCXD3,KIF26A,TMEM170A,WDPCP,EMX2,PDLIM5,GABRG2,RAB30,KIAA1958,NKD1,METTL21A,LSAMP,MYO5A,NEXMIF,GTDC1,WDR37,BTBD3,ZSCAN29,NSD1,CRTC1,KCNK12,AMZ1,ZNF225,URM1,JPH3" MicroRNA hsa-miR-1250:mirSVR_highEffct hsa-miR-1250:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.18E-10 2.90E-06 8.77E-10 8.08E-09 23 133 "ACTN1,MAGI1,TIGD7,CHN1,SLC35F1,VCAN,SLITRK5,KIAA0753,KLHL5,SRRM1,FCGRT,LOXL3,GAREM2,TMEM260,TCP11L1,ATXN7,SS18,RELL2,LGI4,ZNF17,REEP1,RGS7BP,ADAMTSL3" MicroRNA hsa-miR-6844:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.21E-10 2.92E-06 8.83E-10 8.13E-09 21 111 "RNF150,TNRC6C,ARNTL,CA8,CACNA1B,IP6K1,YAF2,ZNF585B,FLT1,MTHFD2,PDE3A,PDPK1,PLCL1,PKIA,ROBO2,TRAPPC13,ALG1,UBE2H,ZNF781,RNF146,GAN" MicroRNA hsa-miR-599:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.21E-10 2.92E-06 8.83E-10 8.13E-09 21 111 "SPOP,GAS7,ARSE,CBR1,UBXN2A,RASGRP1,EIF4G2,ELOVL5,PAX6,PLCL1,ENOX1,ZFHX4,SLC8A1,ATF7IP,SATB2,DOK6,NR2C2,VSNL1,STOX2,NETO2,GAN" MicroRNA hsa-miR-6722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.39E-10 3.01E-06 9.12E-10 8.40E-09 27 181 "ELFN2,RNF157,SEMA7A,HCN2,HEYL,IRAK4,DLC1,PDLIM5,CELF1,GFER,KCNK3,MSI1,PKD1,PLEC,SLC25A23,POLR2F,NCR3LG1,TMEM145,SARS,HES6,SP2,NFASC,CLASP1,ASXL3,GDPD5,ITM2C,HNRNPA3" MicroRNA hsa-miR-500a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-10 3.12E-06 9.43E-10 8.68E-09 24 145 "DNAH17,CCNT1,RGS6,FSD1L,POLR1B,ST6GALNAC3,GABRG2,MTHFD2,PRRC2B,RNF165,HAS2,ZIC5,SLC35G1,MBNL1,MYO5A,GSTCD,PGBD4,SLC8A1,TACC1,SIK3,NR2C2,KCNT2,LYPD6,ZDHHC20" MicroRNA hsa-miR-141-3p:Functional MTI Functional MTI miRTarbase 5.57E-10 3.12E-06 9.43E-10 8.68E-09 24 145 "OGT,SEPT7,QKI,MAP4K4,CLOCK,RASSF2,CELF1,MALT1,IPO5,PPARA,MAPK9,PTPRD,WDR37,ELMO2,TET1,ZNF621,TROVE2,ERBIN,SEPT8,ZEB1,ZFPM2,ZMAT3,TIAM1,CLDND1" MicroRNA hsa-miR-708-5p:TargetScan hsa-miR-708-5p TargetScan 5.64E-10 3.15E-06 9.53E-10 8.78E-09 26 169 "ACHE,AS3MT,RNF150,PDZD4,BEGAIN,MTMR3,CABP7,FOXN3,CNTFR,PITPNM3,GAPVD1,E2F6,FOXO3,GABRA3,CHL1,MUM1,C2orf72,KCNN3,NFE2L2,NNAT,ALG9,CPEB3,IQSEC2,MMS19,CBX5,GDPD5" MicroRNA hsa-miR-28-5p:TargetScan hsa-miR-28-5p TargetScan 5.64E-10 3.15E-06 9.53E-10 8.78E-09 26 169 "ACHE,AS3MT,RNF150,PDZD4,BEGAIN,MTMR3,CABP7,FOXN3,CNTFR,PITPNM3,GAPVD1,E2F6,FOXO3,GABRA3,CHL1,MUM1,C2orf72,KCNN3,NFE2L2,NNAT,ALG9,CPEB3,IQSEC2,MMS19,CBX5,GDPD5" MicroRNA hsa-miR-466:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-10 3.15E-06 9.53E-10 8.78E-09 26 169 "TAOK1,STX16,BACH1,BAG4,CPEB2,CERCAM,TUBA1B,SYT17,COPS8,GLI2,DIDO1,ZNF678,KLHL23,SFXN5,SYTL4,NEXMIF,ZNF827,PIK3R1,PURG,PPP2R5E,C12orf49,ZNF415,NSFL1C,SIK3,NR2C2,UBTF" MicroRNA hsa-miR-663:mirSVR_highEffct hsa-miR-663:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.72E-10 3.20E-06 9.66E-10 8.89E-09 25 157 "SUGT1P4-STRA6LP-CCDC180,SPTBN4,STK33,KALRN,NRXN3,SUMF2,CCDC144A,ELN,GTF2IRD2,MAD2L2,AKAP3,TVP23A,SIGLEC8,LOXL3,MIA2,PEX26,SIRT2,SMARCD3,PRRT1,PIK3R5,PPIL6,PDIA2,PLPPR2,SLC17A7,WNK3" MicroRNA hsa-miR-1224-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.95E-10 3.33E-06 1.01E-09 9.25E-09 19 91 "APBB2,ZBTB10,CACNA1B,GAPVD1,SCML2,SYNCRIP,ANKFY1,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,NMNAT2,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-205-5p:Functional MTI Functional MTI miRTarbase 6.11E-10 3.42E-06 1.03E-09 9.50E-09 27 182 "ABCF1,KCTD16,PHF12,B4GALT6,RGS6,GUCD1,E2F5,PHC2,KLHL5,ERBB2,ZNF585B,ACSL4,SARAF,SHISA6,EID2B,SMAD1,AFF1,SPDL1,LRRK2,CLIP1,CPEB3,BDP1,DMXL2,SATB2,ZEB1,SLC38A1,JMJD1C" MicroRNA "CTCAAGA,MIR-526B:MSigDB" "CTCAAGA,MIR-526B:MSigDB" MSigDB 6.24E-10 3.49E-06 1.05E-09 9.70E-09 17 72 "MTUS1,HECW2,OGT,ARRB1,CAPN3,CPEB2,FGF1,PCDH17,ICA1,MKLN1,ZNF827,CCSER2,STRN3,RGS12,ZFHX4,ROBO1,ARX" MicroRNA hsa-miR-1253:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.37E-10 3.56E-06 1.08E-09 9.90E-09 28 195 "SEMA7A,ARMC12,BTK,ZNF445,ARHGEF6,LETMD1,AKAP5,RNF14,KIAA0040,CHRDL1,SLC43A2,MRVI1,FAM49B,TRAF3IP2,GRB10,LRRC75A,KCNH2,GPR173,FIGN,SLC25A36,SETD5,ARMH4,BTBD3,ASTN2,TUBB2A,RPRM,URM1,ITM2C" MicroRNA hsa-miR-375:mirSVR_highEffct hsa-miR-375:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.43E-10 3.60E-06 1.09E-09 9.99E-09 26 170 "BEND6,LRFN1,OGT,APBB2,EIF4G3,RAB33A,CNN3,PNPLA8,VPS13B,GPHN,SYNCRIP,STAMBP,OGA,GGTA1P,RBPJ,P2RX7,PCSK5,WBP1L,OXR1,ROBO2,FUZ,TET1,UHRF1BP1L,CLASP2,ZFPM2,TRIM9" MicroRNA hsa-miR-8068:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.89E-10 3.86E-06 1.16E-09 1.07E-08 20 102 "ARHGDIA,BAG4,KIAA0408,JAKMIP2,DMD,EIF1,ENPP6,FGF14,JKAMP,HS6ST3,PDPK1,NCR3LG1,MARCH1,SH3TC2,SEMA6D,SEPHS1,PARD3,TNS1,VSNL1,ZNF74" MicroRNA hsa-miR-345:PITA hsa-miR-345:PITA_TOP PITA 6.89E-10 3.86E-06 1.16E-09 1.07E-08 20 102 "USP6,RAB39B,KMT5B,SMAD1,KITLG,MYO5A,SLC11A2,PDE4B,RIPOR1,FIGN,PBRM1,PPM1E,CPEB3,FAM214B,SSTR2,FBXW11,TCF4,TRPS1,SSBP2,FRMD6" MicroRNA hsa-miR-3934-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.23E-10 4.05E-06 1.22E-09 1.12E-08 34 277 "TMEM132B,TAOK1,PHF12,ARRB1,STOML1,SOCS5,FAM131B,MRNIP,TUBA1B,ZNF44,POLL,DDX19B,C2orf72,ZIC5,KCNN1,KCNN3,P2RX7,TMOD2,PIK3C2A,PIGG,NWD1,PRRT2,DCUN1D2,KLHDC8A,HUNK,HSPA4L,ZNF430,ZBTB43,DIP2A,STAC2,GPRIN3,ZNF708,MPPE1,FXR1" MicroRNA hsa-miR-302b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.35E-10 4.11E-06 1.24E-09 1.14E-08 21 113 "USP37,TMEFF1,CLOCK,MYADM,SCRN1,SPATA2,JAKMIP2,TBC1D16,FGF1,AMOTL2,GPR75,TNRC6A,FAM69A,MSANTD3-TMEFF1,LSAMP,OLA1,ZNF793,FNDC3A,BTBD7,EML6,DHX33" MicroRNA hsa-miR-7109-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.37E-10 4.12E-06 1.24E-09 1.14E-08 22 124 "TRMT9B,PRX,ARHGDIA,BCL7A,METTL6,ZNF385A,CRMP1,PYGO1,EIF4G1,ERBB2,CELF1,MTHFD2,GFER,PRRC2B,PLEC,SDK2,DIRAS2,HSD11B1L,ZFP30,NMNAT2,USP22,MGAT5B" MicroRNA hsa-miR-873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.51E-10 4.20E-06 1.27E-09 1.17E-08 25 159 "CC2D2A,TRMT9B,SOCS5,GAPVD1,HEPH,MTX3,ABCC5,EGR3,DCTN4,ZNF549,ZBED3,SIGLEC8,SESN1,DDX19B,KCNN3,GPR173,CCSER2,STK32A,ZNF331,SEPHS1,ERBIN,USP22,RPL7L1,VSNL1,PHTF2" MicroRNA hsa-miR-6878-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-10 4.39E-06 1.32E-09 1.22E-08 32 250 "PPFIA4,CDC14B,EPS15L1,SUMF2,IP6K1,ELMSAN1,SGSM2,SEC16A,MRO,MTSS1L,GLUL,MIER3,KCNK3,SAMD14,GPR137C,GPR173,CCSER2,PLIN1,SDK2,PPARA,PTPRE,SETD5,SEPHS1,ATF7IP,CLSTN2,ZSCAN29,FBXW11,ZNF34,TPM2,WBP2,UBTF,HNRNPA3" MicroRNA hsa-miR-3714:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.90E-10 4.42E-06 1.33E-09 1.23E-08 30 223 "RNF157,HECW2,ZNF582,CBFA2T2,CFL2,QKI,HAPLN1,FAM131B,MRNIP,AMOTL2,MALT1,STARD3,ZNF496,RBPJ,COMMD5,NFIX,NLE1,SMOX,NCR3LG1,SBF1,CPEB3,TROVE2,ZSCAN29,NEK4,SATB2,ERCC6L2,TOM1L2,DPYSL5,EVI5,URM1" MicroRNA hsa-miR-1251-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-10 4.46E-06 1.34E-09 1.24E-08 16 64 "BCL7A,CAMK2A,RTTN,PPP1R16B,SPATA2,CHRDL1,ANKMY1,AMOTL2,MSANTD4,SRCAP,OCRL,C1orf109,RDX,NLGN1,ASTN2,SMARCAD1" MicroRNA hsa-miR-4423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.09E-10 4.53E-06 1.36E-09 1.25E-08 29 210 "AS3MT,TMEM132B,ESYT2,ISPD,AKAP5,CSNK1G3,SEC14L5,MRNIP,COQ7,LILRA2,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,PEX26,FAM126B,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA hsa-miR-3197:mirSVR_highEffct hsa-miR-3197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.57E-10 4.79E-06 1.44E-09 1.33E-08 24 148 "FAM135A,NUMB,ADGRB2,CBLN1,CLCN3,FAM19A5,CNTNAP2,DGKG,SGSM2,STRADA,PSD2,FAM120B,CYP46A1,SLC35G1,MAN2A2,ZSCAN2,KCTD17,SMARCD3,DBNDD2,HIF3A,AMACR,TRIM9,WNK3,NLRP3" MicroRNA hsa-miR-1908:mirSVR_highEffct hsa-miR-1908:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.60E-10 4.81E-06 1.45E-09 1.33E-08 25 160 "SUGT1P4-STRA6LP-CCDC180,SPTBN4,STK33,KALRN,NRXN3,SUMF2,CCDC144A,ELN,GTF2IRD2,MAD2L2,AKAP3,TVP23A,SIGLEC8,C15orf41,LOXL3,MIA2,PEX26,SIRT2,SMARCD3,PRRT1,PIK3R5,PPIL6,PDIA2,SLC17A7,WNK3" MicroRNA hsa-miR-4480:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.63E-10 4.83E-06 1.45E-09 1.34E-08 22 125 "NDRG3,ZBTB10,RGS6,RASSF2,ZNF391,ATP13A4,GATM,CIT,AFF1,SDK2,C1orf109,TMEM231,ACSS3,SLC25A36,RNASEL,SNAP25,DDN,STAC2,TCEA1,ANKRD24,FXR1,NETO2" MicroRNA hsa-miR-6501-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.06E-10 5.07E-06 1.52E-09 1.40E-08 29 211 "AS3MT,TMEM132B,ESYT2,ISPD,AKAP5,CSNK1G3,SEC14L5,MRNIP,COQ7,CELF1,LILRA2,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,FAM126B,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA "ATAACCT,MIR-154:MSigDB" "ATAACCT,MIR-154:MSigDB" MSigDB 9.41E-10 5.27E-06 1.58E-09 1.46E-08 15 56 "MTUS1,OSBPL8,OGT,CAMK2G,FOXN3,SOCS5,E2F5,KAT7,MAP4,CNOT4,SALL1,PPM1E,PKNOX2,TCF12,EVI5" MicroRNA hsa-miR-4697-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.88E-10 5.53E-06 1.66E-09 1.53E-08 20 104 "BCL7A,EVI5L,CBARP,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NFIX,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA "GCACCTT,MIR-18B:MSigDB" "GCACCTT,MIR-18B:MSigDB" MSigDB 9.88E-10 5.53E-06 1.66E-09 1.53E-08 20 104 "ALCAM,DPP10,NCOA1,SOCS5,PHF20L1,SUCO,ADAMTS13,ATXN2L,HSF2,IGF1,KIT,PRKACB,FAM192A,CCDC88A,FNBP1,TEX2,CDK19,CLASP2,MESP1,TRIM2" MicroRNA "GCACCTT,MIR-18A:MSigDB" "GCACCTT,MIR-18A:MSigDB" MSigDB 9.88E-10 5.53E-06 1.66E-09 1.53E-08 20 104 "ALCAM,DPP10,NCOA1,SOCS5,PHF20L1,SUCO,ADAMTS13,ATXN2L,HSF2,IGF1,KIT,PRKACB,FAM192A,CCDC88A,FNBP1,TEX2,CDK19,CLASP2,MESP1,TRIM2" MicroRNA hsa-miR-4485-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-09 5.59E-06 1.68E-09 1.54E-08 27 186 "CLK4,CACNA1A,ZNF385A,ZBTB24,HEYL,TUBD1,SLC43A2,FGFR1,PCYOX1,CRCP,ZNF655,FAM216A,STRN3,EXOSC10,APTX,MTMR10,ZSCAN2,ZNF844,NWD1,PGBD4,SEPHS1,ATF7IP,DIP2A,AGTPBP1,ZMAT3,SSBP2,JMJD1C" MicroRNA hsa-miR-4762-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-09 5.76E-06 1.73E-09 1.59E-08 21 115 "ADD2,CFL2,FOXN3,OSBPL3,CST3,RUSC2,C3orf18,MALT1,RAB30,POLL,L1CAM,LSAMP,NPTX2,KANSL1,PEX2,PGBD4,FNBP1,ZNF74,REEP1,WNK3,FXR1" MicroRNA hsa-miR-146b-3p:PITA hsa-miR-146b-3p:PITA_TOP PITA 1.03E-09 5.76E-06 1.73E-09 1.59E-08 21 115 "DYNLL1,ADGRB1,HAP1,CNTNAP2,DBN1,DYNC1I1,PPP1R1B,BRSK1,LINGO1,MAT2A,NRCAM,RETREG2,TMEM260,OXR1,PPP4R3A,CPEB4,DDN,ST5,ADGRL3,THRA,NAV3" MicroRNA hsa-miR-4666a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-09 6.00E-06 1.80E-09 1.65E-08 18 84 "TNRC6C,BACH1,JAZF1,ISPD,PLXNA4,LIN54,CERCAM,ENPP6,MMADHC,ZDHHC15,C2orf72,KLHL23,P2RY1,FAM98B,GDPD1,SEPHS1,UNC5B,TUBB2A" MicroRNA hsa-miR-3166:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-09 6.00E-06 1.80E-09 1.65E-08 18 84 "SLC24A4,IGDCC4,ARHGDIA,PRC1,COL9A1,PREPL,PLXNA4,IP6K1,ABCC5,CSDC2,FERMT2,PCLO,CYP27C1,AFF1,PLXNB1,CEP97,COPZ1,VSNL1" MicroRNA hsa-miR-4790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-09 6.00E-06 1.80E-09 1.65E-08 18 84 "XKR4,AKAP5,SLC35F1,SV2B,ERBB2,ZNF585B,ATP13A4,STAMBP,PPM1L,NCAM2,SMIM7,PSAT1,SARS,SLC2A5,MBD5,SPART,FAM208A,VSNL1" MicroRNA hsa-miR-34c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-09 6.01E-06 1.80E-09 1.66E-08 26 174 "ZMYM4,EVI5L,FOXN3,MRNIP,APOPT1,GABRA3,POLL,FICD,DDX19B,IL6R,MAP4,MAPT,MKLN1,GIT1,MYCN,CNOT4,COPZ1,CPEB3,SNCA,PEG10,SATB2,TPCN2,SLC35G2,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-3194-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-09 6.15E-06 1.84E-09 1.69E-08 23 138 "AS3MT,ISPD,TBRG4,TBPL1,KIAA0408,DBT,GOLGA7,MSANTD4,GSN,KPNA5,LIMS1,GPR155,MKLN1,PAX6,SEPT4,HSPA4L,KLHL7,ARL10,ERCC6L2,PARD3,ZNF74,ZNF154,WNK2" MicroRNA hsa-miR-4695-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-09 6.17E-06 1.85E-09 1.70E-08 40 370 "ABCF1,ADD2,SLC24A4,MTUS1,CDC14B,ARHGDIA,ZNF583,DDR1,NDST3,NRXN3,SUMF2,LETMD1,MYADM,LIN54,TMEM170A,ELMSAN1,TNK2,ANKMY1,MRVI1,ZNF585B,HHIPL1,SESN1,GPR75,GNG4,ATOH8,PPM1L,NBL1,ZC3H12B,NELL2,PLXNB1,POLR2F,MTMR10,RFX2,ALG9,STUM,FAM102A,SLC2A5,ATF7IP,UNC5B,SLC37A2" MicroRNA hsa-miR-4639-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-09 6.31E-06 1.89E-09 1.74E-08 27 187 "TEX22,MTA3,PHF12,RGS6,LONRF1,DBT,TMCC2,COQ7,GABRG2,KAT7,ATOH8,ZDHHC15,NKD1,SH3TC2,C12orf49,ELP2,CHD9,ZFP1,ANKRD36,ZC3H13,SS18,KLHL4,BHLHB9,SMUG1,UBE2H,ZNF708,GAN" MicroRNA hsa-miR-1238:mirSVR_highEffct hsa-miR-1238:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-09 6.34E-06 1.90E-09 1.74E-08 29 213 "ARNTL,ADAM23,IL33,MAGI1,LHX2,AKAP7,RGS6,CSNK1G3,GAPVD1,BRINP1,GIT2,JAKMIP2,EXOG,EIF1,EPHB1,SMC2,NSG1,DISC1,MSTN,CIT,ZNF92,NFIX,ENPP2,CARF,ARMH4,SLC8A1,ANKRD36,RGMB,TUBB1" MicroRNA hsa-miR-4488:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.59E-06 1.97E-09 1.82E-08 20 105 "BCL7A,EVI5L,CBARP,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NFIX,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA hsa-miR-587:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.59E-06 1.97E-09 1.82E-08 20 105 "AK2,ZBTB10,RUNX1T1,SEPT7,CDH2,HDAC4,RCAN1,LYVE1,AFF1,NCR3LG1,ZDHHC14,MSANTD2,CSRNP3,TBCEL,USP22,NR2C2,RUNDC3B,VSNL1,DHX33,JMJD1C" MicroRNA hsa-miR-302a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.60E-06 1.97E-09 1.82E-08 22 127 "CDC14B,LONRF2,CDR1,QKI,CPS1,USP6NL,SACS,FEM1B,SUCO,CBX1,IGF1,SLC35G1,CREG2,NEK1,PIK3R1,PSAT1,ZMAT4,ELP2,AP1AR,FAM126B,ZNF70,SLC30A4" MicroRNA hsa-miR-4689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.60E-06 1.97E-09 1.82E-08 22 127 "APBB2,CACNA1B,GAPVD1,SEC16A,EIF1,MRVI1,SYNCRIP,PDLIM5,METTL21A,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,NMNAT2,PEG10,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-524-3p:mirSVR_highEffct hsa-miR-524-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-09 6.60E-06 1.97E-09 1.82E-08 22 127 "NUMB,ARHGAP32,GOLT1B,EBF1,FCGRT,ATP2C1,CRCP,COPS8,AGBL5,AQP11,NTRK3,MAPKAP1,RASGRF2,PRRT2,GTDC1,KIAA0895L,HSD11B1L,SH3BGR,ZC3H13,DDN,ADGRL3,MTMR14" MicroRNA hsa-miR-6747-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-09 6.79E-06 2.03E-09 1.87E-08 21 116 "MARCH4,ARHGDIA,CRLF1,ZNF385A,PYGO1,IP6K1,DBT,ELN,GLI2,PRRC2B,GRIN2D,MPP2,MYO5A,MAPK10,SETD5,KLHDC8A,ATXN2,CAMTA2,UBTF,RICTOR,ZDHHC20" MicroRNA hsa-miR-451:mirSVR_highEffct hsa-miR-451:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.22E-09 6.80E-06 2.03E-09 1.87E-08 30 227 "BEND6,CC2D2A,CDC14B,B4GALT6,RRAGB,SESN1,MSL3,KDM2B,MCHR1,ZBTB49,TCEAL6,RBPJ,ZNF678,MBP,DPY19L2P2,MAGEL2,PTPRE,SETD5,SGK1,MYO16,ZNF423,KLHL7,SYNE2,ADGRL3,CUX2,AKTIP,TK2,TCEAL7,ZNF184,EMSY" MicroRNA hsa-miR-7162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-09 6.82E-06 2.03E-09 1.87E-08 26 175 "APAF1,CCNT1,SUMF2,GREB1,LONRF1,TMTC1,IRAK4,CELF1,CRCP,LUZP2,LILRA2,MMP17,BLOC1S2,THYN1,SFR1,NUCB2,OPRL1,ALG9,ATXN2,PEG10,MCF2L2,NEK4,SYT1,SLC19A3,TUBB2A,ZDHHC20" MicroRNA hsa-miR-4775:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-09 6.88E-06 2.05E-09 1.89E-08 35 297 "SYT13,USP37,PTBP2,LETMD1,RIMS4,MYADM,FARSB,RASA4,C8orf37,RAB9B,NCALD,AMOTL2,SEC23B,PCYOX1,PPARGC1A,MALT1,ZNF276,KIAA1958,PRRC2B,GRIK4,PAXBP1,GPR155,MBNL1,TM6SF1,MXI1,PLCL1,SH3KBP1,FAM161B,SLC8A1,AGTPBP1,KIAA0930,SSBP2,ZFP37,KCNT2,ZDHHC20" MicroRNA hsa-miR-518f:PITA hsa-miR-518f:PITA_TOP PITA 1.24E-09 6.91E-06 2.06E-09 1.90E-08 13 41 "ZNF608,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,SOCS4" MicroRNA hsa-miR-518c:PITA hsa-miR-518c:PITA_TOP PITA 1.24E-09 6.91E-06 2.06E-09 1.90E-08 13 41 "ZNF608,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,SOCS4" MicroRNA hsa-miR-518a-3p:PITA hsa-miR-518a-3p:PITA_TOP PITA 1.24E-09 6.91E-06 2.06E-09 1.90E-08 13 41 "ZNF608,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,SOCS4" MicroRNA hsa-miR-518b:PITA hsa-miR-518b:PITA_TOP PITA 1.24E-09 6.91E-06 2.06E-09 1.90E-08 13 41 "ZNF608,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,SOCS4" MicroRNA hsa-miR-518d-3p:PITA hsa-miR-518d-3p:PITA_TOP PITA 1.24E-09 6.91E-06 2.06E-09 1.90E-08 13 41 "ZNF608,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,SOCS4" MicroRNA hsa-miR-490-3p:Functional MTI Functional MTI miRTarbase 1.27E-09 7.08E-06 2.11E-09 1.94E-08 29 214 "XKR4,TRMT9B,CDC14B,ASPA,MTMR3,CBFA2T2,LONRF2,CDR1,GREB1,RASA4,IRAK4,MRNIP,ZNF549,TRMO,ERGIC3,DISC1,LILRA2,DDX19B,RBPJ,IBA57,PPM1L,MYO5A,QDPR,PGBD4,CDK19,NFASC,FAM208A,CLASP1,BHLHB9" MicroRNA hsa-miR-8084:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-09 7.19E-06 2.14E-09 1.97E-08 19 95 "CDC14B,STX16,QKI,BAG4,C8orf37,ACSL4,CELF1,SESN1,FERMT2,GPR137C,PKD1,MAPK7,GDPD1,ZFHX4,ROBO2,MBD5,ZNF621,ZMAT3,TUBB2A" MicroRNA hsa-miR-3911:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-09 7.19E-06 2.14E-09 1.97E-08 19 95 "ADCY5,CARNS1,CACNA1A,TMEM184B,IGLON5,DCAF8,TMEM130,DMTF1,MRPL37,CAMKK2,GPT2,NKD1,MAP2,MAT2A,SDK2,SATB1,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-942-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.29E-09 7.19E-06 2.14E-09 1.97E-08 28 201 "GALNT13,ADD1,SPOP,ATP1A3,GPR146,CABP7,IGLON5,GAPVD1,RASSF2,CDON,RGS17,EMX2,COQ7,PCDH17,ZNF638,IBA57,LSAMP,PDE3A,GNG2,SNRK,TMLHE,CSRNP3,ANKRD28,EXOC7,MGRN1,TLR4,TNS1,DPF3" MicroRNA hsa-miR-615-5p:PITA hsa-miR-615-5p:PITA_TOP PITA 1.30E-09 7.30E-06 2.17E-09 2.00E-08 16 66 "SEMA6A,CABP1,CLIP3,RGS6,RIMS4,DMPK,APH1A,AGAP2,SYT3,GGT7,CAMK2N2,MEF2C,MEIS2,NFIX,PPP5C,MAPK10" MicroRNA "GTGGTGA,MIR-197:MSigDB" "GTGGTGA,MIR-197:MSigDB" MSigDB 1.30E-09 7.30E-06 2.17E-09 2.00E-08 16 66 "PCDH19,ANK2,BCL7A,RAB28,DNM1,PHF20L1,AGAP2,GRIA2,KCND2,ZNF827,MAPK4,FBXW7,PPM1E,NLGN1,TAL1,ADGRL3" MicroRNA "GGGATGC,MIR-324-5P:MSigDB" "GGGATGC,MIR-324-5P:MSigDB" MSigDB 1.34E-09 7.49E-06 2.23E-09 2.05E-08 14 49 "MAP4K3,ADGRB1,ING4,GGT7,BACH2,KCND2,NTRK3,SEPT4,FBXO11,TMCC1,ZHX3,SEPT3,THRA,GAN" MicroRNA hsa-miR-6515-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-09 8.02E-06 2.38E-09 2.19E-08 27 189 "SPOP,GPR146,STOML1,PITPNM3,UBXN2A,PLCXD3,GAPVD1,CENPL,C2CD2L,FCF1,ZNF391,SCML2,TMEM175,CELF1,NSG1,GABRG2,IBA57,NOVA2,NPTX1,KSR2,PKIA,PTPRN2,EPN2,LIMCH1,PEG10,CYB561A3,PRDM10" MicroRNA hsa-miR-6840-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-09 8.21E-06 2.44E-09 2.25E-08 45 452 "ABCF1,PTCHD1,MTA3,HACE1,APAF1,CPNE5,AQP6,CBS,CCPG1,SUMF2,RTTN,ZNF385A,RNF14,PYGO1,MYADM,IP6K1,MTX3,DNAH9,CNNM1,HEYL,MRO,ANKMY1,ZNF589,MSANTD4,KIAA1958,GNG4,BACH2,AGBL5,IGF1,NKD1,IL6R,NFIX,FAM216A,NCR3LG1,ZNF844,CEP97,MSANTD2,RGS12,CSRNP3,TRIM67,ATF7IP,ERCC6L2,TSPAN11,LAT2,INTS3" MicroRNA hsa-miR-4477a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-09 8.22E-06 2.44E-09 2.25E-08 23 140 "BRAP,BBOX1,SEMA7A,FOXN3,FEM1B,PLEKHA1,ACSL4,SCML2,MTHFD2,GRB10,MIER3,ZIC5,LIMS1,PDPK1,PSAT1,GDPD1,RPL15,CLIP1,SLC6A8,DOCK9,CBX5,UGT8,GAL3ST3" MicroRNA hsa-miR-3658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-09 8.35E-06 2.48E-09 2.28E-08 24 152 "TAOK1,ZBTB10,LDLRAD4,LIN54,SCRN1,EIF4G2,TENM1,ACSL4,MIER3,LIFR,NCAM2,PIK3R1,EPB41L4B,GDPD1,ZNF844,CEP97,SETD5,BTBD7,TMCC1,ITPRID2,TLR4,UGT8,MPPE1,FZD3" MicroRNA hsa-miR-6716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-09 8.66E-06 2.57E-09 2.37E-08 19 96 "TPP1,PPP1R16B,USP6NL,SV2B,HEYL,IRAK4,AMOTL2,NEURL4,DDX19B,GLIPR1L2,CNTLN,TMEM145,GTDC1,NMNAT2,MTMR14,CBX5,WBP2,UBC,UBTF" MicroRNA hsa-miR-4735-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-09 8.66E-06 2.57E-09 2.37E-08 19 96 "AS3MT,RNF157,PTCHD1,TAOK1,CA12,TBPL1,DCAF4,DCAF8,LIN54,KLHL3,ZNF585B,AGFG1,ZNF678,MBD1,PCDH9,PDE4D,PSAT1,ITM2C,RNF146" MicroRNA hsa-miR-601:PITA hsa-miR-601:PITA_TOP PITA 1.61E-09 9.01E-06 2.67E-09 2.46E-08 15 58 "TMEM132B,ADGRB1,SYNGR3,ZNF385A,KDM2B,CIT,MIER3,SNRK,SH3TC2,FIGN,MCMBP,R3HDM2,SOX11,SIRT1,ZBTB38" MicroRNA hsa-miR-298:Functional MTI Functional MTI miRTarbase 1.66E-09 9.29E-06 2.75E-09 2.54E-08 25 165 "XKR4,ADD1,ESYT2,AK2,PHF12,ARHGDIA,ZBTB10,ST3GAL5,HAP1,AKAP5,DNAL1,ENPP6,ZNF589,GABRB3,SRRM4,GLUL,GRB10,RNF165,COMMD5,CCSER2,QDPR,NSD1,UBTF,USP1,ZNF138" MicroRNA hsa-miR-1260:PITA hsa-miR-1260:PITA_TOP PITA 1.66E-09 9.29E-06 2.75E-09 2.54E-08 25 165 "ADCY6,CDC42BPA,PTBP2,CDH2,SOCS6,HECTD1,ZNF385A,CRY2,PLCXD3,ALKBH8,ETV1,SUCO,PPARGC1A,NEXMIF,NFIX,RXRA,NCBP3,AMBRA1,CPEB4,NMNAT2,CDK19,ZIC1,EMSY,FXR1,RNF146" MicroRNA hsa-miR-1237-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.67E-09 9.33E-06 2.76E-09 2.55E-08 20 107 "BCL7A,EVI5L,CBARP,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NFIX,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA hsa-miR-220a:mirSVR_highEffct hsa-miR-220a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-09 9.39E-06 2.78E-09 2.56E-08 21 118 "KLHL32,PWWP2A,DDR1,CACNA2D1,CACNA2D2,DNM1,ZNF589,GLI2,GNAO1,ZBTB49,IL6ST,ZFYVE27,PTPRN2,KANSL3,CPEB4,NXT2,COBL,TPCN2,C9orf85,TRIO,KAT6A" MicroRNA hsa-miR-1247-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-09 9.44E-06 2.79E-09 2.57E-08 38 345 "RNF157,SLC24A4,LRFN1,CDC14B,SFMBT2,PLAA,KIAA0408,TMEM170A,DNAL1,SLC43A2,STX2,ZNF585B,FKTN,PDLIM5,BRSK1,CRCP,GPR75,LIMS1,CCSER2,MTMR10,ZNF793,NWD1,RBBP8,ALG9,SNX22,RPS6KA2,PTGR2,ZFP30,SLC2A5,MCF2L2,LHPP,TPCN2,ZNF106,SSBP2,USP1,ZNF70,EVI5,PARP11" MicroRNA hsa-miR-6083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-09 9.89E-06 2.93E-09 2.70E-08 26 178 "ZNF608,HACE1,C4orf33,QKI,TBPL1,HINFP,MYADM,DGKG,PITPNC1,CDON,FARSB,FEM1B,MSANTD4,PPARGC1A,TNRC6A,BACH2,LIFR,PRIMA1,MYCBP2,PRRC2C,SYP,AGTPBP1,SIK3,NR2C2,MAP3K12,ZXDA" MicroRNA "GTCAGGA,MIR-378:MSigDB" "GTCAGGA,MIR-378:MSigDB" MSigDB 1.80E-09 1.01E-05 2.98E-09 2.74E-08 14 50 "ABR,OGT,ATP2B2,FOXN3,CAMKK2,SHC3,NF1,NFIX,LRP12,CEP41,ROBO2,CCDC88A,KBTBD4,TOM1L2" MicroRNA hsa-miR-4434:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-09 1.01E-05 2.99E-09 2.75E-08 28 204 "TRMT9B,CDC14B,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,KIAA1958,BACH2,IDH3A,KCND1,KCNH2,MAP2,SAMD14,GPR137C,GPR173,SLC25A36,CLSTN2,ASTN2,FBXW11,ZNF34,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-5703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-09 1.01E-05 2.99E-09 2.75E-08 28 204 "TRMT9B,CDC14B,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,KIAA1958,BACH2,IDH3A,KCND1,KCNH2,MAP2,SAMD14,GPR137C,GPR173,SLC25A36,CLSTN2,ASTN2,FBXW11,ZNF34,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-548az-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-09 1.06E-05 3.12E-09 2.88E-08 25 166 "XKR4,PTCHD1,PHF12,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CFL2,CLOCK,ENTPD4,STARD3NL,SCML2,SUCO,RNPS1,SCIN,KANSL1,GRAMD1C,DIRAS2,TMLHE,TUBB2A,EML6,SMARCAD1,NHSL1" MicroRNA hsa-miR-1201:PITA hsa-miR-1201:PITA_TOP PITA 1.90E-09 1.06E-05 3.14E-09 2.89E-08 17 77 "ATP1A1,GAPVD1,NYAP1,TENM1,UFM1,ZNF638,MBNL1,MEIS1,TRHDE,SCHIP1,TEX2,ELOVL4,TTBK2,ZC3H4,SATB2,ZFPM2,ZIC1" MicroRNA hsa-miR-191:PITA hsa-miR-191:PITA_TOP PITA 1.90E-09 1.06E-05 3.14E-09 2.89E-08 17 77 "PITPNM2,ATP2B2,B4GALT6,PHC2,FRY,EMX2,MSI1,NPTX2,NRCAM,TMOD2,ZNF532,SAFB,SATB1,TET1,ELOVL4,HEY1,MAP3K12" MicroRNA hsa-miR-202-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-09 1.09E-05 3.23E-09 2.98E-08 18 87 "ZNF578,GAS7,RUNX1T1,LONRF2,CNN3,USP3,COQ7,COPS8,ZDHHC15,IBA57,MARCH1,ZFP30,PRRC2C,TRPS1,RICTOR,FAM13C,FXR1,JPH3" MicroRNA hsa-miR-4693-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-09 1.11E-05 3.27E-09 3.01E-08 20 108 "KLHL32,PPFIA4,TMEM184B,CSF1,ARHGEF4,MRO,BVES,SYNPO,NKD1,SLC35G1,ZFYVE27,CHIC1,SAMD5,NUCB2,PFKFB2,OLA1,NKAIN1,NCBP3,TMCC1,SLC19A3" MicroRNA hsa-miR-4516:Functional MTI Functional MTI miRTarbase 2.02E-09 1.13E-05 3.34E-09 3.07E-08 28 205 "TRMT9B,CDC14B,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,KIAA1958,BACH2,IDH3A,KCND1,KCNH2,MAP2,SAMD14,GPR137C,GPR173,SLC25A36,CLSTN2,ASTN2,FBXW11,ZNF34,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-4467:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-09 1.17E-05 3.46E-09 3.18E-08 16 68 "PRX,DNAH17,CBARP,ELMSAN1,EIF4G1,MTSS1L,CPLX1,MSI1,PKD1,FXYD1,PEG10,SSTR1,ARC,WSCD1,CLASP1,CELF4" MicroRNA hsa-miR-552-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-09 1.20E-05 3.54E-09 3.26E-08 25 167 "TXNDC16,AK2,TAOK1,PHF12,TTLL9,RUNX1T1,PLAA,SOCS5,IRAK4,MRNIP,ERBB2,TUBA1B,ZNF44,GABRB3,GPR137C,PFKFB2,PKM,C12orf49,HSPA4L,SGK1,DIP2A,ARL10,NACC2,MPPE1,AP3B2" MicroRNA hsa-miR-422a:PITA hsa-miR-422a:PITA_TOP PITA 2.16E-09 1.21E-05 3.57E-09 3.29E-08 22 131 "KSR1,AHCTF1,CLOCK,HDAC4,HIPK3,CELSR3,MED12L,GABRG2,GPT2,ZHX1,KIF2A,NTRK3,PDE4D,PDE1B,VSTM2L,RAP1GDS1,SPIN3,NSFL1C,SYN2,DMXL2,TCF12,ZFPM2" MicroRNA hsa-miR-378:PITA hsa-miR-378:PITA_TOP PITA 2.16E-09 1.21E-05 3.57E-09 3.29E-08 22 131 "KSR1,AHCTF1,CLOCK,HDAC4,HIPK3,CELSR3,MED12L,GABRG2,GPT2,ZHX1,KIF2A,NTRK3,PDE4D,PDE1B,VSTM2L,RAP1GDS1,SPIN3,NSFL1C,SYN2,DMXL2,TCF12,ZFPM2" MicroRNA hsa-miR-1324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-09 1.21E-05 3.57E-09 3.29E-08 22 131 "SLC24A4,CALM1,PRC1,TMEM184B,COL9A1,IP6K1,SPATA2,ZNF274,MTHFD2,CSDC2,RNPS1,FERMT2,MUM1,BACH2,HSF2,AFF1,KSR2,P2RX7,PDE4D,PLXNB1,NBPF1,URM1" MicroRNA hsa-miR-4801:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-09 1.25E-05 3.67E-09 3.38E-08 19 98 "LDHD,CACNA2D1,QKI,FBXL5,CPEB2,NEU3,SESN1,DIDO1,ZIC5,ZNF678,SFXN5,THYN1,MYO6,P2RY1,PPP2R5E,ROBO2,SBF1,TPM2,GAN" MicroRNA hsa-miR-5584-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-09 1.26E-05 3.71E-09 3.41E-08 23 143 "RNF157,OGT,PHF12,LDHD,TM9SF4,GTF2IRD2,CAMKK2,TNRC6A,STMN1,SCAMP5,NPTX2,ZNF827,CNNM2,SLC25A36,LHPP,SSTR1,ZSCAN29,ARL10,UBE2H,MGAT5B,URM1,ITM2C,HNRNPA3" MicroRNA hsa-miR-202-3p:Functional MTI Functional MTI miRTarbase 2.26E-09 1.26E-05 3.72E-09 3.43E-08 28 206 "FZD9,IGDCC4,BACH1,ARHGAP22,E2F6,EDN1,CELF1,POLL,FUT10,HAS2,MIER3,IL6R,THYN1,MYCN,NUCB2,OPRL1,USP47,RDX,FIGN,ATXN2,FNDC3A,PEG10,MCF2L2,TROVE2,SYT1,KIAA0930,SLC19A3,CBX5" MicroRNA hsa-miR-1185-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-09 1.29E-05 3.80E-09 3.50E-08 21 120 "ZNF608,PITPNM2,VAT1L,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,NCOA7,MBNL1,PCSK1,PFKFB2,TMEM104,ROBO1,PKNOX2,KIF13A,DIP2A,GPRIN3,USP1" MicroRNA hsa-miR-2115-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-09 1.33E-05 3.91E-09 3.60E-08 18 88 "RALGAPA1,ZBTB10,BACH1,VXN,FCF1,ELN,JKAMP,MSANTD4,HSF2,AFF1,TCEAL5,PDE3A,HSPA4L,ZNF621,SATB2,ZMAT3,MTCH1,ZBTB38" MicroRNA hsa-miR-4487:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-09 1.35E-05 3.98E-09 3.67E-08 29 220 "ZNF578,TRMT9B,AMH,GAS7,USP37,CCPG1,UBXN2A,DNAL1,E2F6,STX2,FGFR1,RNPS1,HSF2,PLEC,ALG9,CCDC25,MAP6D1,FNIP1,PEX26,MYH15,ERC1,NFASC,LHPP,APOM,CYB561A3,THRA,TMEM9,PPIL6,USP1" MicroRNA hsa-miR-296-5p:mirSVR_highEffct hsa-miR-296-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-09 1.35E-05 3.98E-09 3.67E-08 29 220 "PTCHD1,LRFN1,CDC14B,CCAR2,P2RX6,KCNAB3,NUMBL,CNTFR,SUMF2,NYAP1,PHC2,YAF2,CELSR3,TAOK3,KAT8,MAD2L2,TXNL4A,RAB30,MAP7D2,PSIP1,HMGCL,PCSK5,GPR173,ZDHHC8,PPP1R1A,SHC4,CDK5RAP3,LMO3,OBSL1" MicroRNA hsa-miR-136*:mirSVR_highEffct hsa-miR-136*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-09 1.36E-05 4.00E-09 3.69E-08 25 168 "KLHL32,UNC79,LINC00173,BACH1,KALRN,CAST,SRSF11,AKAP12,DDX46,HS3ST2,SIRPB1,SEC24B,OLFM1,PSD2,PCLO,STMN2,HAS2,UBE2QL1,MBD1,MIA2,CNTLN,SLC14A1,SNRPN,ADHFE1,MTCL1" MicroRNA hsa-miR-4483:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-09 1.40E-05 4.12E-09 3.80E-08 22 132 "TAOK1,ARHGDIA,BCL7A,ZNF445,CSNK1E,PLEKHA1,ELN,MTSS1L,ANKFY1,CRCP,RNPS1,NFIX,PLEC,SKOR1,CEP97,PRRT2,SETD5,C12orf49,RMI1,TPCN2,UBTF,SLC38A1" MicroRNA hsa-miR-4257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.58E-09 1.44E-05 4.24E-09 3.91E-08 40 381 "ABCF1,NDRG3,HECW2,CARNS1,TRMT9B,ATP1B3,MTMR3,DDR1,CBFA2T2,CCPG1,EPS15L1,NRXN3,POM121,ANKRD46,RASA4,MRNIP,SLC43A2,ANKMY1,KATNAL1,MTHFD2,GATM,CSDC2,CRCP,GNG4,KAT7,DDX19B,ZNF546,IBA57,TMOD2,PLEC,ALG9,GSTCD,GALNT10,FAM102A,MYO18A,ATF7IP,NEK4,NACC2,BHLHB9,ZNF70" MicroRNA hsa-miR-361-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.58E-09 1.45E-05 4.25E-09 3.91E-08 23 144 "MARCH4,LRFN1,LGR5,ARHGDIA,ARRB2,SH2B1,LRIG1,VCAN,TBC1D5,IP6K1,DMPK,MRPL37,APC2,IP6K2,SEMA4D,GPD1,LSAMP,NFYA,VWA2,KSR2,ZC3H4,ALG1,CIAPIN1" MicroRNA hsa-miR-513b-5p:Functional MTI Functional MTI miRTarbase 2.58E-09 1.45E-05 4.25E-09 3.91E-08 23 144 "TXNDC16,ZNF583,ZNF555,TOGARAM2,GREB1,TM9SF4,SYTL4,ZNF713,MAGEL2,NCR3LG1,CSRNP3,SH3BP2,POGZ,DIP2A,ANKRD28,IQCE,NSD1,RPL7L1,TFIP11,SLC38A1,HNRNPA3,PHTF2,FXR1" MicroRNA hsa-miR-296-5p:PITA hsa-miR-296-5p:PITA_TOP PITA 2.63E-09 1.47E-05 4.33E-09 3.98E-08 16 69 "UNC5A,LRFN1,PPFIA3,CCAR2,GPC2,CNTFR,CLIP3,MED12,TAOK3,AHDC1,RNF165,CYB561D1,SOX11,SLC30A3,PCBP4,ADAMTS10" MicroRNA hsa-miR-1296-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-09 1.49E-05 4.37E-09 4.03E-08 19 99 "ARRB2,UBXN2A,IP6K1,TOM1,ING4,SESN1,MIER3,TJAP1,IBA57,PFKFB2,PKM,SMOX,KIAA0895L,SBF1,SCN2B,COPZ1,BTBD3,SLC19A3,UBTF" MicroRNA hsa-miR-448:Functional MTI Functional MTI miRTarbase 2.66E-09 1.49E-05 4.37E-09 4.03E-08 19 99 "THSD7A,TBPL1,USP6NL,DAPK1,ACSL4,MMADHC,COPS8,KDM2B,P2RY1,PIK3R1,PURG,CEP97,SETD5,SATB1,HSPA4L,ZBTB43,SS18,SEPT8,FXR1" MicroRNA hsa-miR-4731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-09 1.49E-05 4.37E-09 4.03E-08 19 99 "LDHD,CACNA2D1,QKI,FBXL5,CPEB2,NEU3,SESN1,DIDO1,ZIC5,ZNF678,SFXN5,THYN1,MYO6,P2RY1,PPP2R5E,ROBO2,SBF1,TPM2,GAN" MicroRNA hsa-miR-3607-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-09 1.49E-05 4.37E-09 4.03E-08 19 99 "ABCD2,MARCH4,ARNTL,STX16,FOXN3,QKI,FAM107B,EIF4G2,PLEKHA1,SCML2,CELF1,GRIK4,MIER3,PBRM1,CHD9,CPEB4,CLSTN2,EVI5,ZDHHC20" MicroRNA "CTAGGAA,MIR-384:MSigDB" "CTAGGAA,MIR-384:MSigDB" MSigDB 2.69E-09 1.50E-05 4.41E-09 4.06E-08 15 60 "PCDH19,HFM1,CHRD,FOXN3,SLC35F1,RIMS4,RIMS2,POM121,UBE2E3,ATP2C1,GFRA2,PRKACB,PTN,FBXO11,ERBIN" MicroRNA "TATCTGG,MIR-488:MSigDB" "TATCTGG,MIR-488:MSigDB" MSigDB 2.69E-09 1.50E-05 4.41E-09 4.06E-08 15 60 "PCDH19,CDK13,NCOA1,ATP1A1,NRXN3,CNN3,CREM,RCAN2,LIFR,PDE4D,FBXW7,CPEB3,SATB2,RPGRIP1L,NAV3" MicroRNA hsa-miR-6895-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.86E-09 1.60E-05 4.69E-09 4.32E-08 26 182 "SPAG9,CBARP,USP6NL,TMEM170A,C2CD2L,RCAN1,UFM1,DISC1,SYTL4,LSAMP,PALM,PDE3A,RDX,NCBP3,SCN2B,TRA2B,ZFP30,FAM214B,UNC5B,MCF2L2,DIP2A,TAL1,FAM208A,SZT2,ZNF708,PLSCR4" MicroRNA "AGGTGCA,MIR-500:MSigDB" "AGGTGCA,MIR-500:MSigDB" MSigDB 2.88E-09 1.61E-05 4.71E-09 4.34E-08 18 89 "OGT,CHRD,NCOA1,SEC24C,MATR3,PLPPR4,CELSR3,ING4,DCTN4,NBEA,GABRB3,CIT,HLF,PPP2R5E,PPP3CC,FIGN,FBXW7,ADAMTSL3" MicroRNA "AGCTCCT,MIR-28:MSigDB" "AGCTCCT,MIR-28:MSigDB" MSigDB 2.88E-09 1.61E-05 4.71E-09 4.34E-08 18 89 "ACHE,NDRG2,UNC5A,PDZD4,AMPH,CABP7,FOXN3,QKI,CNTFR,CSF1,EPHB1,RNF165,MAT2A,ZC3H12B,NNAT,IQSEC2,TRPS1,KAT6A" MicroRNA hsa-miR-3942-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-09 1.62E-05 4.73E-09 4.36E-08 17 79 "NUMB,TBPL1,BAG4,CPEB2,YAF2,SESN1,TNRC6A,IL6ST,RBBP6,FIGN,SETD5,KCNIP3,MPRIP,RGMB,RPL7L1,VSNL1,GAN" MicroRNA hsa-miR-2116-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-09 1.63E-05 4.76E-09 4.39E-08 24 157 "PWWP2A,PTCHD1,PHF12,ARSE,ZNF582,CASTOR3,CAMK2G,EXOG,HIPK3,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,SRRM4,AP4S1,NFYA,GDPD1,ZNF844,UHRF1BP1L,SMUG1,RUNDC3B,TSPAN11,DPYSL5,GAN" MicroRNA hsa-miR-6826-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-09 1.63E-05 4.76E-09 4.39E-08 24 157 "ASGR1,ASPA,NUMBL,CYBB,KLHL5,STARD3NL,CELF1,SEPT9,KCNMB4,FAM107A,PADI2,SHISA6,RDX,GTDC1,SETD5,ZFP1,ZHX3,NSFL1C,THRA,ZNF24,URM1,PPP1R3F,ITM2C,NETO1" MicroRNA hsa-miR-423-3p:mirSVR_highEffct hsa-miR-423-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.14E-09 1.76E-05 5.14E-09 4.74E-08 21 122 "LINC00847,CAMK2A,CNOT8,NDST3,CREM,RHOBTB1,DTNA,FRY,KAT8,POLK,AP4S1,HNMT,KCNN3,MEIS1,SLC11A2,EPB41L4B,FIGN,SYT1,MLST8,PRRT1,ATP6V0E2" MicroRNA hsa-miR-411:PITA hsa-miR-411:PITA_TOP PITA 3.18E-09 1.78E-05 5.20E-09 4.79E-08 19 100 "DPP10,WASF1,CACNB4,CDH2,CCPG1,MAP4K4,PUM1,FBXL5,KLHL3,EIF4G2,GKAP1,SOX11,SP2,SP4,TRPS1,ZFAND5,NAV3,WNK3,HNRNPA3" MicroRNA hsa-miR-6857-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.25E-09 1.82E-05 5.32E-09 4.90E-08 20 111 "ELFN2,CBARP,KIAA0040,DBN1,ZC3H11A,MTX3,MRNIP,FGF1,TDRKH,RNF165,PDE4D,KCTD15,ATP8B4,FAM126B,ZNF621,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-09 1.88E-05 5.48E-09 5.05E-08 22 134 "LTBP4,CCAR2,CAMK2A,RUNX1T1,NRXN3,TMEM184B,APC2,TBC1D16,TUBA1B,GTF2IRD2,MAP7D2,GPER1,TNFAIP8L3,CHST6,OCRL,POLR2F,PEAR1,TRIM67,KDM4B,SATB2,TMEM9,CIAPIN1" MicroRNA hsa-miR-6509-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-09 1.93E-05 5.63E-09 5.18E-08 15 61 "FAM135A,PTBP2,CCNT1,FOXN3,TMEM170A,CELF1,IL6R,SLC35G1,MYCN,SNX10,PPP1R1A,CNNM2,BTBD3,AP4E1,RICTOR" MicroRNA hsa-miR-144-3p:Functional MTI Functional MTI miRTarbase 3.50E-09 1.96E-05 5.71E-09 5.26E-08 28 210 "TAOK1,STX16,CPS1,SPATA2,ZC3H11A,RAB39B,GOLGA7,ACSL4,STAMBP,DIDO1,FAM69A,LIFR,MBNL1,MKLN1,MYCN,MYO5A,NFE2L2,ZNF827,TUG1,OXR1,FBXW7,FNDC3A,ATF7IP,ANKRD12,ZEB1,RPL7L1,WNT7A,WRN" MicroRNA "TTGGGAG,MIR-150:MSigDB" "TTGGGAG,MIR-150:MSigDB" MSigDB 3.55E-09 1.98E-05 5.79E-09 5.33E-08 17 80 "PKP4,MYADM,C2CD2L,KLHL3,POM121,PLXNC1,GABRG2,ICA1,IGF1,KCNN3,PRRT2,ATAT1,TMCC1,FBXW11,TRPS1,ZNF189,MAP3K12" MicroRNA hsa-miR-1273f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-09 2.09E-05 6.10E-09 5.62E-08 34 295 "TMEM132B,MTA3,SEMA7A,C6orf89,CDC25B,KIAA0586,JAKMIP2,FARSB,PLEKHA1,C8orf37,TRAF3IP2,GLUL,POLL,PRRC2B,GPR155,ZNF426,PPP2R5E,GDPD1,CEP97,ELP2,PTGR2,HSD11B1L,SCN2B,FAM102A,NUBPL,FAM126B,ALG1,KIAA0930,SSBP2,TUBB2A,RPL7L1,LAT2,ZNF708,STOX2" MicroRNA hsa-miR-497-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.78E-09 2.12E-05 6.17E-09 5.68E-08 19 101 "BACH1,ABCG2,PITPNC1,DPP6,MAMLD1,TMTC1,GABRB3,PRRC2B,SHISAL1,FAM69A,THYN1,NWD1,ELP2,TMEM200C,TRA2B,NFASC,SLC30A3,SLC30A4,NETO1" MicroRNA hsa-miR-134-5p:Functional MTI Functional MTI miRTarbase 3.78E-09 2.12E-05 6.17E-09 5.68E-08 19 101 "FMNL2,ELFN2,USP37,CA12,KIAA0040,RCAN1,MRNIP,ERBB2,TRMO,TJAP1,IL6ST,POLR2F,PEX26,FAM126B,ZNF621,PUM2,ZNF106,KAT6B,UPF3A" MicroRNA "AAACCAC,MIR-140:MSigDB" "AAACCAC,MIR-140:MSigDB" MSigDB 3.78E-09 2.12E-05 6.17E-09 5.68E-08 19 101 "GALNT16,ZNF608,OGT,ANK2,ZBTB10,BACH1,USP6,CSNK1G3,HDAC4,PHF20L1,EPHB1,LOXL3,CIT,KCND2,TTYH2,GIT1,PRIMA1,R3HDM1,NAV3" MicroRNA hsa-miR-3065-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.83E-09 2.14E-05 6.24E-09 5.75E-08 20 112 "STX16,CDC25B,TOGARAM2,PPP1R16B,RIMS2,ING4,C2orf72,KCNN1,ENPP2,GPSM2,CEP97,MAPKBP1,ZC3H4,SLC37A2,CLASP1,CBX5,TUBB2A,ZNF45,TMEM237,URM1" MicroRNA hsa-miR-1293:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-09 2.17E-05 6.31E-09 5.81E-08 22 135 "TAOK1,ARHGDIA,BCL7A,ZNF445,CSNK1E,PLEKHA1,ELN,MTSS1L,ANKFY1,CRCP,RNPS1,NFIX,PLEC,SKOR1,CEP97,PRRT2,SETD5,C12orf49,RMI1,TPCN2,UBTF,SLC38A1" MicroRNA hsa-miR-2110:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-09 2.17E-05 6.31E-09 5.81E-08 22 135 "USP2,TPP1,NCOR2,MRO,SRCAP,NXPH3,MIER3,SCIN,MSI1,NBL1,PFKFB2,FXYD1,EPB41L4B,WBP1L,KIAA0895L,SBF1,COPZ1,UNC5B,POGZ,CBX5,ZNF708,CIAPIN1" MicroRNA hsa-miR-188-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-09 2.17E-05 6.31E-09 5.81E-08 22 135 "RNF150,MTA3,OSBPL1A,PHF12,BACH1,IP6K1,MRPL37,RAPGEF6,HAS2,MN1,PNMA3,SDK2,CNNM2,PEX2,SPIN3,STUM,KIF21A,KANSL3,WBP2,ZNF711,GDPD5,GAN" MicroRNA hsa-miR-4673:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.89E-09 2.18E-05 6.34E-09 5.84E-08 23 147 "LTBP4,APAF1,DNAH17,DDR1,NUMBL,ANKMY1,POLR1B,C15orf41,FUT10,RNF165,IRAK3,CREG2,CDK18,QDPR,ELP2,PEAR1,SH3BP2,R3HDM2,PEX26,TRIM67,ARC,SLC37A2,AMZ1" MicroRNA hsa-miR-3154:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.89E-09 2.18E-05 6.34E-09 5.84E-08 23 147 "MTUS1,TRMT9B,OGT,TMEM184B,ZC3H11A,ING4,CRCP,POLL,MIER3,IDH3A,SCAMP5,MKLN1,SAMD14,TMEM104,NWD1,PRRT2,ANKRD36,STX1A,USP22,ZNF34,ARL10,TPM2,URM1" MicroRNA hsa-miR-181a*:mirSVR_highEffct hsa-miR-181a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.89E-09 2.18E-05 6.34E-09 5.84E-08 23 147 "OSBPL8,TNRC6C,CALB2,THSD7A,LOC730101,MAGI1,CFL2,KIF26A,ARMCX4,RHOBTB1,ATP13A4,GPD1,HMGCL,KCNN2,RTL5,GRAMD1C,RGS3,ROBO1,ABCA11P,SCN8A,KIF13A,TRERF1,SMUG1" MicroRNA hsa-miR-6818-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-09 2.23E-05 6.50E-09 5.98E-08 25 172 "SPAG9,SOCS6,BAG4,USP6NL,TMEM170A,C2CD2L,HEYL,UFM1,SYTL4,LSAMP,PALM,PDE3A,SMIM7,PIGG,CNTLN,NCBP3,TRA2B,FAM214B,MCF2L2,DIP2A,FAM208A,SZT2,VLDLR,ZNF708,PLSCR4" MicroRNA hsa-miR-566:mirSVR_highEffct hsa-miR-566:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.11E-09 2.30E-05 6.70E-09 6.16E-08 16 71 "ADAM15,CAMK2G,EIF1,DLC1,GABRB3,SESN1,LOXL3,PLCD4,GIT1,PIGG,PEG10,CAMTA2,UGT8,OSBP2,TRIM9,MPPE1" MicroRNA hsa-miR-664a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-09 2.34E-05 6.81E-09 6.27E-08 18 91 "KIAA1211,CDK13,CALM1,EDN1,PTPRT,HLF,ZNF678,SLC35G1,MAGEL2,TMLHE,MEG3,CHD9,ZNF667,ZNF415,VLDLR,WNT7A,ZNF23,SIGLEC10" MicroRNA hsa-miR-579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-09 2.40E-05 6.96E-09 6.41E-08 24 160 "BRAP,KIAA1211,CDK13,CALM1,APPL1,TENM1,EPHB1,CAMKK2,FUT9,KIAA1841,INSYN1,MAGEL2,PKIA,ACSS3,RNASEL,SETD5,TMLHE,CCDC25,FBXW7,ZNF331,TRAPPC13,TROVE2,PRDM10,TMEM63C" MicroRNA hsa-miR-4304:mirSVR_highEffct hsa-miR-4304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.34E-09 2.43E-05 7.05E-09 6.49E-08 17 81 "FAM135A,PITPNM2,CDK10,ARHGEF7,TIGD7,RAB33A,SLC4A8,DNM1,KMT5B,ANKMY1,CEP78,COPS8,RAB30,NEFH,KAT6B,STXBP4,VLDLR" MicroRNA hsa-miR-4703-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.34E-09 2.43E-05 7.05E-09 6.49E-08 17 81 "NUMB,TBPL1,BAG4,CPEB2,YAF2,SESN1,TNRC6A,IL6ST,RBBP6,FIGN,SETD5,KCNIP3,MPRIP,RGMB,RPL7L1,VSNL1,GAN" MicroRNA "CCAGGTT,MIR-490:MSigDB" "CCAGGTT,MIR-490:MSigDB" MSigDB 4.39E-09 2.46E-05 7.14E-09 6.57E-08 15 62 "OGT,ARHGAP33,AHCTF1,GGT7,MSI1,OXR1,GTDC1,PBRM1,FAM219A,SOX11,CAMTA1,SZT2,NR2C2,SLC35A4,GAL3ST3" MicroRNA hsa-miR-137:Non-Functional MTI Non-Functional MTI miRTarbase 4.45E-09 2.49E-05 7.24E-09 6.66E-08 23 148 "FMNL2,BMP7,DCLK1,DBN1,ZNF804A,ZC3H11A,E2F6,EGFR,EIF1,COQ7,ZDHHC15,ZNF678,KIT,SFXN5,MITF,MSI1,SNRK,RASGRF1,FNIP1,LIMCH1,ITPRID2,ZNF24,LYPD6" MicroRNA hsa-miR-6765-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.46E-09 2.49E-05 7.24E-09 6.67E-08 22 136 "SLC2A11,BACH1,CCNT1,CCPG1,SEC14L5,DNAH9,EIF4G1,MRNIP,COQ7,MRPL10,CEP78,MSANTD4,ZNF274,CPLX2,RBPJ,MMP17,SFR1,MAPK9,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-3149:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.50E-09 2.52E-05 7.31E-09 6.73E-08 25 173 "RNF150,ZMYM4,PUM1,HDAC4,EIF5,C8orf37,PDLIM5,ZNF276,PTPRT,SLC2A6,DDX19B,MIER3,HNF4G,PLCL1,GDPD1,NWD1,FIGN,FAM161B,TMCC1,ZEB1,GPRIN3,FAM200B,SSBP2,ZNF711,ZNF195" MicroRNA hsa-miR-6876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.50E-09 2.52E-05 7.31E-09 6.73E-08 27 199 "ELFN2,TAOK1,SEMA4G,CNN3,IP6K1,DBN1,SPATA2,PHC2,AMOTL2,SUCO,STARD3,PRRC2B,ZNF496,TNFAIP8L3,ZFYVE27,BLOC1S2,NOVA2,ZNF426,TRIM67,SYPL1,USP22,NACC2,WBP2,RGMB,UBTF,TSPAN11,WRN" MicroRNA hsa-miR-4476:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.50E-09 2.52E-05 7.31E-09 6.73E-08 27 199 "ELFN2,TAOK1,SEMA4G,CNN3,IP6K1,DBN1,SPATA2,PHC2,AMOTL2,SUCO,STARD3,PRRC2B,ZNF496,TNFAIP8L3,ZFYVE27,BLOC1S2,NOVA2,ZNF426,TRIM67,SYPL1,USP22,NACC2,WBP2,RGMB,UBTF,TSPAN11,WRN" MicroRNA hsa-miR-6131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-09 2.53E-05 7.32E-09 6.74E-08 29 226 "TMEM132B,CCAR2,TMEM184B,BAG4,SEC14L5,MYADM,DNAJB6,FEM1B,CRCP,FERMT2,DDX19B,KCNN3,CYP27C1,MAN2A2,MYO5A,MYO6,ZNF426,ZMAT4,C12orf49,SGSM1,NUBPL,ANKRD36,FAM126B,ZBTB43,SSTR2,CYB561A3,ZNF34,SGK3,ZNF70" MicroRNA hsa-miR-548at-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.94E-09 2.77E-05 8.02E-09 7.38E-08 21 125 "TAOK1,ZBTB10,PTBP2,DNAL1,RCAN2,POLR1B,FUT10,MAP4K5,MAT2A,MMP16,CEP97,ROBO1,TROVE2,ANKRD28,FAM208A,SIRT1,NACC2,CBX5,ZNF70,ZNF138,DHX33" MicroRNA hsa-miR-625-5p:Functional MTI Functional MTI miRTarbase 5.00E-09 2.80E-05 8.10E-09 7.46E-08 29 227 "TAOK1,ARHGDIA,CALM1,CAMK2A,METTL6,TMEM184B,DUSP9,MTHFD2,GLUL,PRRC2B,NXPH3,KCNH2,CHST6,NFIX,NTRK3,PKM,ZNF426,DIRAS2,BDNF-AS,IQSEC3,SHMT2,PKNOX2,FNBP1,ZNF34,TUBB2A,UBTF,CLIP2,RICTOR,ITM2C" MicroRNA hsa-miR-30e-3p:Functional MTI Functional MTI miRTarbase 5.08E-09 2.84E-05 8.23E-09 7.58E-08 25 174 "CDK13,ENTPD4,MAML1,YTHDC1,FAM107B,EIF1,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,KCTD6,EPB41L4B,PPP2R2B,SH3TC2,CCDC25,SCP2,GALNT10,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2,FAM47E" MicroRNA hsa-miR-6165:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.13E-09 2.87E-05 8.31E-09 7.65E-08 22 137 "SFMBT2,ZBTB10,CS,PPP1R16B,UBXN2A,RUBCN,IST1,HEYL,DCTN4,POLR1B,ATOH8,KIF5A,PPM1L,CNNM2,ALG9,NCBP3,SEMA6D,ZC3H4,SLC19A3,HIF3A,NACC2,RPRM" MicroRNA hsa-miR-139-3p:mirSVR_highEffct hsa-miR-139-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.32E-09 2.97E-05 8.61E-09 7.93E-08 19 103 "MARCH4,PRC1,PPP6R2,IP6K1,EGFR,OLFM1,SMC2,INPP5K,NDP,SMIM11A,OGG1,DUSP26,FUZ,CAMTA2,TRIM2,ELP5,RUSC1,RPL7L1,URM1" MicroRNA hsa-miR-520f-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-09 2.97E-05 8.61E-09 7.93E-08 19 103 "RNF157,SORCS2,OSBPL8,BACH1,CAMK2A,PRC1,IGDCC3,ZNF385A,GREB1,FEM1B,MSANTD4,MALT1,IL6ST,KCNB1,LRP12,PRKACB,RAD51D,RGMB,NR2C2" MicroRNA hsa-miR-216a-5p:Functional MTI Functional MTI miRTarbase 5.51E-09 3.08E-05 8.91E-09 8.21E-08 24 162 "CLK4,AS3MT,MTA3,APAF1,CPS1,UBXN2A,MRNIP,COQ7,SEC23B,ZNF638,KDM2B,JAK2,PPM1L,MITF,SMIM7,CNNM2,ZNF793,ATF7IP,SP4,ELOVL4,ALG1,SLC19A3,SIRT1,TUBB2A" MicroRNA hsa-miR-664b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-09 3.08E-05 8.91E-09 8.21E-08 24 162 "BRAP,KIAA1211,CDK13,CALM1,APPL1,TENM1,EPHB1,CAMKK2,FUT9,KIAA1841,INSYN1,MAGEL2,PKIA,ACSS3,RNASEL,SETD5,TMLHE,CCDC25,FBXW7,ZNF331,TRAPPC13,TROVE2,PRDM10,TMEM63C" MicroRNA hsa-miR-652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-09 3.08E-05 8.91E-09 8.21E-08 24 162 "MTA3,PHF12,KIF1A,DOCK11,CARS,CBS,QKI,CNN3,POM121,SLC12A6,TUBA1B,AGAP3,TMEM107,TNRC6A,KDM2B,CHST6,MRAS,ATF7IP,ZEB1,GPR161,EIF4ENIF1,LAT2,GDPD5,GAN" MicroRNA hsa-miR-96-5p:Functional MTI Functional MTI miRTarbase 5.61E-09 3.14E-05 9.08E-09 8.36E-08 27 201 "ADCY6,TAOK1,ALK,JAZF1,SCARB1,ARHGEF2,BAG4,PITPNM3,APPL1,CDON,EIF4G1,TUBD1,PRMT5,FOXO3,MALT1,TNRC6A,MITF,NPTX1,PFKFB3,ANKRD36,CAMTA1,SIN3B,ZEB1,TMPO,SGK3,RPL7L1,EVI5" MicroRNA hsa-miR-3150a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.72E-09 3.20E-05 9.25E-09 8.52E-08 25 175 "CASKIN1,ARRB1,CBS,TPP1,RGS6,ABCC5,ING4,SRCAP,TNRC6A,SHISA6,SOWAHA,SCIN,MSI1,NBL1,GPR173,C12orf49,RPS6KA2,UNC5B,CLSTN2,CAMTA2,SLC19A3,CBX5,UBTF,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-6763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.72E-09 3.20E-05 9.25E-09 8.52E-08 25 175 "CASKIN1,ARRB1,CBS,TPP1,RGS6,ABCC5,ING4,SRCAP,TNRC6A,SHISA6,SOWAHA,SCIN,MSI1,NBL1,GPR173,C12orf49,RPS6KA2,UNC5B,CLSTN2,CAMTA2,SLC19A3,CBX5,UBTF,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-6804-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-09 3.20E-05 9.26E-09 8.52E-08 21 126 "TXNDC16,ARRB1,CDC25B,CACNA2D2,EPS15L1,DOT1L,SEPT9,TNRC6A,GRIN2D,NFIX,PKM,PLCD1,PLEC,RETREG2,PPP2R2B,PKIA,MORC4,GALNT10,STX1A,SLC38A1,ACTR3B" MicroRNA hsa-miR-3191:mirSVR_highEffct hsa-miR-3191:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.73E-09 3.20E-05 9.26E-09 8.52E-08 21 126 "VWA5B2,ABR,PCDH10,TTLL9,E2F5,TBC1D16,BRSK1,B4GALNT1,LRRC37A6P,LOXL3,PRDM5,MAN2A2,GPR137C,KIF16B,SMARCD3,ADHFE1,TRPM2,FAM155A,SPHK2,CELF4,SLC17A7" MicroRNA hsa-miR-6894-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.75E-09 3.22E-05 9.28E-09 8.55E-08 26 188 "APAF1,ARHGDIA,SUMF2,CS,CSF1,TMTC1,GLYR1,ZBTB45,NEGR1,KIF5A,MAT2A,KSR2,PKM,SMIM7,PLXNB1,POLG,PPP2R5E,MTMR10,MSANTD2,KLHDC8A,SOX11,PEG10,DBNDD2,WBP2,WRN,ZNF17" MicroRNA hsa-miR-578:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-09 3.25E-05 9.37E-09 8.62E-08 23 150 "TAOK1,SPAG9,DLGAP2,VCAN,SOCS5,FEM1B,EPHB1,ACSL4,DLC1,TPPP,KLHL23,LOH12CR2,TM6SF1,TMOD2,OLA1,GALNT10,CXXC4,MGRN1,ZMAT3,DOK6,CADM2,SLC38A1,KCNAB1" MicroRNA hsa-miR-451b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-09 3.25E-05 9.37E-09 8.62E-08 23 150 "ARMC12,TPP1,AKAP12,PUM1,TMEM170A,TRMO,CRCP,GPR75,MSL1,CREG2,LAMP2,LIFR,CHST6,ADAM22,SLC11A2,KLHDC8A,PEX26,IQCE,CRTC1,ZMAT3,SMUG1,SSBP2,TBC1D15" MicroRNA hsa-miR-6835-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.89E-09 3.30E-05 9.51E-09 8.76E-08 22 138 "KIAA0408,DCAF8,ELMSAN1,CELF1,CIT,ELOVL5,SYNPO,METTL21A,NFYA,PDE4D,PDPK1,PLEC,KLHL11,ROBO1,SEC31A,FAM126B,HECW1,NXT2,KIAA0930,USP22,ZXDA,URM1" MicroRNA hsa-miR-193b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.94E-09 3.32E-05 9.58E-09 8.82E-08 28 215 "ADD1,TAOK1,TRMT9B,C6orf89,BMP7,DIS3L,AKAP6,SOCS5,KIAA0586,WDPCP,PDLIM5,TNRC6A,POLL,ZNF491,RBPJ,STMN1,GPR155,SDK2,GDPD1,ZNF793,C12orf49,PTGR2,PUM2,ZNF708,ZNF24,ZNF138,MSRB3,GAN" MicroRNA hsa-miR-493-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.15E-09 3.44E-05 9.92E-09 9.14E-08 20 115 "PWWP2A,HIP1R,USP2,TBRG4,SOCS5,TBC1D5,SARAF,ZDHHC15,L1CAM,PCSK1,PDPK1,C12orf49,FNIP1,TRA2B,SP4,PRRC2C,AGTPBP1,TRIM2,SLC44A1,EVI5" MicroRNA hsa-miR-640:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.25E-09 3.50E-05 1.01E-08 9.28E-08 27 202 "AS3MT,BRAP,ZNF578,TAOK1,STOML1,EIF5,APOPT1,HAS2,C2orf72,MAN2A2,CHST6,P2RX7,TMOD2,ZNF426,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,NUBPL,ZNF430,ANKRD36,TMCC1,ZBTB43,ZNF34,USP1,ZNF708,MPPE1" MicroRNA hsa-miR-6743-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-09 3.52E-05 1.01E-08 9.33E-08 19 104 "ELFN2,SYT13,OGT,PHF12,ARHGDIA,CAMK2A,SPATA2,AHDC1,CRCP,POLL,HS6ST3,PKD1,MTRF1L,TMCC1,NSD1,PUM2,TUBB2A,RPL7L1,URM1" MicroRNA hsa-miR-6748-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.32E-09 3.54E-05 1.02E-08 9.38E-08 16 73 "DPY19L3,CCNT1,PITPNM3,TM9SF4,C2CD2L,TOM1,POLL,SYNPO,MAP4,MEIS1,N6AMT1,PALM,SCN2B,SMARCC2,PCDHA6,SIGLEC10" MicroRNA hsa-miR-875-5p:TargetScan hsa-miR-875-5p TargetScan 6.32E-09 3.54E-05 1.02E-08 9.38E-08 16 73 "METAP1D,CASKIN1,LDLRAD4,RUNX1T1,CLOCK,EGFR,EYA1,NEGR1,AQP11,PDE4D,IQSEC3,PPM1E,PEG10,FAM208A,SATB2,HNRNPA3" MicroRNA hsa-miR-21-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-09 3.59E-05 1.03E-08 9.52E-08 17 83 "ZNF608,ARNTL,CALM1,ELMO1,KMT5B,CELF1,ZNF546,L1CAM,SMAD1,MAT2A,NCAM2,GPR137C,ZNF793,SALL1,SGK1,SOX11,CLASP1" MicroRNA hsa-miR-769-5p:PITA hsa-miR-769-5p:PITA_TOP PITA 6.42E-09 3.59E-05 1.03E-08 9.52E-08 17 83 "ZFYVE16,ELMSAN1,PSD2,CIT,KAT7,SYNPO,SCAMP5,RTL5,LRP12,TMEM260,KIRREL1,AMBRA1,WDR37,SLC12A4,SYP,TBL1X,RGS7BP" MicroRNA hsa-miR-369-5p:mirSVR_lowEffct hsa-miR-369-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.59E-09 3.69E-05 1.06E-08 9.76E-08 28 216 "SPTBN4,SGCE,SLC25A14,ZFP28,GIT2,CALCRL,ZSCAN30,ATP13A4,TMEM107,GPD2,PCLO,AP4S1,SFR1,NLE1,MAPK9,PTPRE,KLHL11,ATAT1,NCBP3,SALL1,HKDC1,DZIP1,SLC14A1,COBL,TIAM1,HIRA,HPS4,JMJD1C" MicroRNA hsa-miR-544a:Functional MTI Functional MTI miRTarbase 6.61E-09 3.70E-05 1.06E-08 9.79E-08 23 151 "WDR35,CC2D2A,SPOP,STX16,CAPN3,DLGAP2,CLTC,DCAF8,TMEM170A,EPB41,MTSS1L,ATOH8,PPM1L,GPR137C,DUSP26,PIK3C2A,RFX3,FNDC3A,STXBP1,ASTN2,SYT5,PCDHAC2,INTS3" MicroRNA "GCAAGGA,MIR-502:MSigDB" "GCAAGGA,MIR-502:MSigDB" MSigDB 7.03E-09 3.93E-05 1.13E-08 1.04E-07 15 64 "OGT,RIMS4,DAPK1,KLHL3,ING4,PAN3,AKAP3,DOT1L,ZMAT1,RAB30,KITLG,MID1,MXI1,PDPK1,RIMBP2" MicroRNA hsa-miR-609:PITA hsa-miR-609:PITA_TOP PITA 7.03E-09 3.93E-05 1.13E-08 1.04E-07 15 64 "ZNF385A,TMEM164,TMEM107,USP21,TTBK1,MEF2C,PDPK1,TMEM145,KIRREL1,CCDC88A,TMCC1,PDZRN3,SIRT1,AMACR,ZIC2" MicroRNA hsa-miR-3684:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.09E-09 3.97E-05 1.14E-08 1.05E-07 9 19 "QKI,POM121,PRRC2B,IFI16,KITLG,BTBD3,EXOC7,PUM2,CFAP298" MicroRNA hsa-miR-18b-5p:Functional MTI Functional MTI miRTarbase 7.18E-09 4.02E-05 1.15E-08 1.06E-07 20 116 "AS3MT,RNF157,PTCHD1,TAOK1,CA12,TBPL1,DCAF4,DCAF8,LIN54,KLHL3,ZNF585B,AGFG1,IGF1,ZNF678,MBD1,PCDH9,PDE4D,PSAT1,ITM2C,RNF146" MicroRNA hsa-miR-299-3p:TargetScan hsa-miR-299-3p TargetScan 7.19E-09 4.02E-05 1.16E-08 1.06E-07 18 94 "ADD1,MARCH3,RUNX1T1,IGLON5,PRAM1,KAT7,IGF1,KNDC1,PAXBP1,GIT1,MSI1,GNG2,CSRNP3,ATXN2,HECW1,CAMTA2,EXOC7,MAP3K12" MicroRNA hsa-miR-212-3p:Functional MTI Functional MTI miRTarbase 7.19E-09 4.02E-05 1.16E-08 1.06E-07 18 94 "ACHE,TNRC6C,ABCG2,UBXN2A,PHF20L1,IRAK4,ACSL4,TJAP1,LIFR,PTCH1,SH3TC2,SETD5,SOX11,CRTC1,SGK3,ZNF711,PARP11,FXR1" MicroRNA hsa-miR-6776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.20E-09 4.03E-05 1.16E-08 1.07E-07 26 190 "TXNDC16,PDZD4,ZNF555,SOCS5,UBXN2A,MTX3,ZBED3,RNPS1,MPP2,STK32A,PEX2,CEP97,PRRT2,KCNIP3,AMBRA1,MYH15,MBD5,MCF2L2,SSTR2,ZSCAN29,SSBP2,USP1,DHX33,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-4688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.41E-09 4.15E-05 1.19E-08 1.10E-07 19 105 "ELFN2,SYT13,OGT,PHF12,ARHGDIA,ATP1B3,CAMK2A,SPATA2,AHDC1,CRCP,POLL,HS6ST3,PKD1,MTRF1L,TMCC1,NSD1,TUBB2A,RPL7L1,URM1" MicroRNA hsa-miR-6885-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.41E-09 4.15E-05 1.19E-08 1.10E-07 19 105 "TXNDC16,TRMT9B,PRX,ARHGDIA,BCL7A,ZNF385A,PYGO1,ERBB2,MTHFD2,GFER,NFIX,PLEC,SDK2,HSD11B1L,NMNAT2,USP22,UBTF,MGAT5B,VGF" MicroRNA hsa-miR-28-5p:Functional MTI Functional MTI miRTarbase 7.41E-09 4.15E-05 1.19E-08 1.10E-07 19 105 "CNN3,CS,E2F6,NRN1,PCYOX1,AHDC1,PRRC2B,RNF165,IGF1,KCNH2,RETREG2,KLHL11,MYH15,IQSEC2,ZNF106,THRA,IL34,TUBB2A,AAAS" MicroRNA hsa-miR-3691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.41E-09 4.15E-05 1.19E-08 1.10E-07 19 105 "ZBTB10,RGS6,DCAF8,ELMSAN1,SEC16A,EDIL3,CELSR3,EIF1,ANKFY1,TXNL4A,ATXN2L,KCNK3,AFF1,GTDC1,ATXN2,MPRIP,STAC2,TNS1,LAT2" MicroRNA hsa-miR-1308:PITA hsa-miR-1308:PITA_TOP PITA 7.41E-09 4.15E-05 1.19E-08 1.10E-07 19 105 "OSBPL8,TMEFF1,MARK4,ALKBH8,CPEB2,DPYSL2,DCTN4,ACSL4,PPARGC1A,RAB30,KITLG,MITF,TCEAL5,NLGN3,ZSCAN32,TMEM255A,ADAMTS17,TAL1,NR2E1" MicroRNA hsa-miR-4701-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-09 4.17E-05 1.19E-08 1.10E-07 30 245 "TAOK1,C6orf89,AKAP6,LRIG1,CSNK1E,MYADM,KIAA0586,COQ7,CEP78,TRMO,CRCP,COPS8,SLC2A6,DDX19B,ZNF678,CYP27C1,MYO6,FBXW7,SGSM1,PTGR2,SATB1,PEX26,FAM126B,LHPP,ALG1,AGTPBP1,ZNF70,URM1,AP3B2,GAN" MicroRNA hsa-miR-342-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-09 4.29E-05 1.23E-08 1.13E-07 21 128 "CRLF1,ZNF385A,IP6K1,ELN,RNPS1,GLI2,PRRC2B,MPP2,MAPK10,PTPRG,RIPOR1,KIF7,KLHDC8A,ROBO2,MCMBP,ATXN2,SMARCA4,NMNAT2,PRRC2C,ANKRD12,UBTF" MicroRNA hsa-miR-6515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-09 4.29E-05 1.23E-08 1.13E-07 21 128 "ADCY5,CASKIN1,CS,RASSF2,SPATA2,FGFR1,DOT1L,SRCAP,NEGR1,NFIX,PKM,POLG,SETD5,KIAA0895L,AMBRA1,GPRIN3,NACC2,WBP2,TUBB2A,CLDND1,SMARCAD1" MicroRNA hsa-miR-449b-5p:Functional MTI Functional MTI miRTarbase 7.75E-09 4.34E-05 1.24E-08 1.14E-07 22 140 "ZMYM4,EVI5L,FOXN3,MRNIP,APOPT1,POLL,FICD,DDX19B,MAP4,MKLN1,MYCN,CNOT4,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,SIRT1,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-379-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-09 4.35E-05 1.25E-08 1.15E-07 17 84 "CCDC74A,ATP1B3,JAZF1,FSD1L,TUBD1,SCML2,MMADHC,SH3TC2,ALG9,PGBD4,FBXW7,FNIP1,SYPL1,FAM182B,ACTR3B,FXR1,NETO2" MicroRNA hsa-miR-6072:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-09 4.35E-05 1.25E-08 1.15E-07 17 84 "C3orf14,CFAP410,CLTC,IGDCC3,ERBB2,MRPL37,ANKMY1,GCK,PCDH17,KCNN1,NCR3LG1,PEX2,STX1B,VLDLR,DHX33,URM1,GAN" MicroRNA hsa-miR-3118:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-09 4.35E-05 1.25E-08 1.15E-07 17 84 "FMNL2,ELFN2,USP37,CA12,KIAA0040,RCAN1,MRNIP,TRMO,TJAP1,IL6ST,POLR2F,PEX26,FAM126B,ZNF621,ZNF106,KAT6B,UPF3A" MicroRNA hsa-miR-4659b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.80E-09 4.36E-05 1.25E-08 1.15E-07 16 74 "CD38,PITPNM3,BOC,DBN1,EBF1,ZNF274,FAM98B,GDPD1,NWD1,SALL1,SEPHS1,BTBD7,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-4659a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.80E-09 4.36E-05 1.25E-08 1.15E-07 16 74 "CD38,PITPNM3,BOC,DBN1,EBF1,ZNF274,FAM98B,GDPD1,NWD1,SALL1,SEPHS1,BTBD7,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-1262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-09 4.46E-05 1.28E-08 1.17E-07 24 165 "TXNDC16,TAOK1,CDC14B,ZNF555,SOCS5,MTX3,EIF5,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,UNC5B,MCF2L2,SSTR2,NACC2,SSBP2,USP1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-548f-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-09 4.46E-05 1.28E-08 1.17E-07 24 165 "XKR4,PTCHD1,PHF12,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,STARD3NL,SCML2,SUCO,RNPS1,SCIN,KANSL1,GRAMD1C,DIRAS2,TMLHE,TUBB2A,EML6,SMARCAD1,NHSL1" MicroRNA hsa-miR-6794-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-09 4.46E-05 1.28E-08 1.17E-07 24 165 "RNF157,SORCS2,EVI5L,DUSP9,EIF4G1,AFF2,CELF1,GLUL,MPP2,NBL1,CCSER2,BDNF-AS,IQSEC3,PRRT2,SETD5,EMID1,SARS,SHMT2,NMNAT2,ERC1,SSTR1,ZNF34,THRA,ITM2C" MicroRNA "CAGTCAC,MIR-134:MSigDB" "CAGTCAC,MIR-134:MSigDB" MSigDB 8.05E-09 4.50E-05 1.29E-08 1.18E-07 13 47 "ASIC1,CSNK1G3,CPEB2,TTBK1,GNAO1,KAT7,MAT2A,MBNL1,MYCN,MTCL1,ADGRL3,ZFPM2,SMARCAD1" MicroRNA hsa-miR-1260b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-09 4.69E-05 1.34E-08 1.23E-07 32 275 "RNF150,MTA3,OSBPL1A,APBB2,BACH1,CACNA1A,PRC1,GAPVD1,RIPOR2,IP6K1,EIF4G1,TNK2,MRPL37,MN1,OGG1,RETREG1,PKM,PSAT1,CNNM2,GSTCD,RPE,SPIN3,SCP2,STUM,KIF21A,DHX30,KANSL3,JMJD6,UGT8,MTCH1,HNRNPA3,GAN" MicroRNA hsa-miR-3973:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.55E-09 4.78E-05 1.37E-08 1.26E-07 23 153 "SMIM17,DMD,HIPK3,FRY,CELSR3,PLEKHA1,RGS17,COQ7,SCML2,SEMA4D,MSANTD4,CHST6,PPP2R5E,KLHL11,ZNF354C,ATF7IP,CEP68,ATMIN,ARL10,TMPO,VLDLR,ZBTB38,FXR1" MicroRNA hsa-miR-6888-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.55E-09 4.78E-05 1.37E-08 1.26E-07 23 153 "CDC14B,SFMBT2,ARSE,ZNF555,LRIG1,PITPNM3,PLCXD3,GAPVD1,RASSF2,SGSM2,KATNAL1,TRAF3IP2,SYTL4,LSAMP,KSR2,GLIPR1L2,PDE3A,BDP1,ADAMTS17,EXOC7,SZT2,SLC38A1,ZDHHC20" MicroRNA hsa-miR-7854-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.55E-09 4.78E-05 1.37E-08 1.26E-07 23 153 "CBS,CFL2,SUMF2,DUSP9,TMTC1,APH1A,FGFR1,CELF1,NEURL4,CRCP,SLC6A17,DIRAS2,PTPRB,C12orf49,FAM102A,MAPKBP1,SOX11,SP2,DDN,NACC2,SSBP2,TUBB2A,ZDHHC20" MicroRNA hsa-miR-671-3p:mirSVR_highEffct hsa-miR-671-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.83E-09 4.94E-05 1.41E-08 1.30E-07 15 65 "ASPHD1,CLK4,UPRT,SEC11C,GOLGA7,FGF11,NOP56,GNAO1,MTRF1L,RASGRF1,ARMC5,CUX2,TEK,MAP3K12,DOCK8" MicroRNA "ATCTTGC,MIR-31:MSigDB" "ATCTTGC,MIR-31:MSigDB" MSigDB 8.83E-09 4.94E-05 1.41E-08 1.30E-07 15 65 "CADPS,NUMB,ELMSAN1,TMEM35A,ADAM28,BACH2,NNAT,IGSF11,STRN3,PTPRE,SNX22,MPRIP,PLCB1,TACC1,FZD3" MicroRNA hsa-miR-548ar-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.00E-09 5.04E-05 1.44E-08 1.32E-07 24 166 "XKR4,PTCHD1,PHF12,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,STARD3NL,SCML2,SUCO,RNPS1,SCIN,KANSL1,GRAMD1C,DIRAS2,TMLHE,TUBB2A,EML6,SMARCAD1,NHSL1" MicroRNA hsa-miR-548e-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.00E-09 5.04E-05 1.44E-08 1.32E-07 24 166 "XKR4,PTCHD1,PHF12,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,STARD3NL,SCML2,SUCO,RNPS1,SCIN,KANSL1,GRAMD1C,DIRAS2,TMLHE,TUBB2A,EML6,SMARCAD1,NHSL1" MicroRNA "TCCCCAC,MIR-491:MSigDB" "TCCCCAC,MIR-491:MSigDB" MSigDB 9.07E-09 5.07E-05 1.45E-08 1.33E-07 14 56 "SEMA4G,PUM1,C2CD2L,PLPPR4,DMPK,APH1A,GPD1,KAT7,ATXN2L,ITPKA,MEIS2,MN1,MAPKAP1,SEMA6D" MicroRNA "GGTGAAG,MIR-412:MSigDB" "GGTGAAG,MIR-412:MSigDB" MSigDB 9.07E-09 5.07E-05 1.45E-08 1.33E-07 14 56 "FMNL2,ANK2,PKP4,PRX,RAB28,ARMC8,ELMSAN1,TAOK3,DLC1,FOXO3,FAM222A,SATB1,IQSEC2,NKAIN2" MicroRNA hsa-miR-3187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.08E-09 5.08E-05 1.45E-08 1.33E-07 29 233 "CARNS1,C6orf89,AKAP6,LRIG1,CSNK1E,MYADM,KIAA0586,DBT,COQ7,TRMO,CRCP,DDX19B,ZNF678,CYP27C1,DBNL,MYO6,PKM,SGSM1,PTGR2,RMI1,PEX26,FAM126B,LHPP,SSTR2,ALG1,AGTPBP1,TUBB2A,ZNF70,GAN" MicroRNA hsa-miR-3151-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.39E-09 5.26E-05 1.50E-08 1.38E-07 17 85 "TRMT9B,AMPD3,CACNA2D2,TMEM184B,PYGO1,TOM1,ELN,MAP4,PLEC,SLC25A23,SDK2,KIAA0895L,ATXN2,SCN2B,COPZ1,PEG10,NACC2" MicroRNA "AGGGCCA,MIR-328:MSigDB" "AGGGCCA,MIR-328:MSigDB" MSigDB 9.58E-09 5.36E-05 1.53E-08 1.40E-07 16 75 "USP37,PRX,NRP2,HAP1,DYNC1I1,AFF2,ATXN2L,VSIG4,LRRC75A,ZC3H12B,SNRK,SCN2B,SOX11,ZNF423,SEPT3,PLCB1" MicroRNA hsa-miR-4524b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-08 5.60E-05 1.59E-08 1.47E-07 29 234 "TEX22,ARHGDIA,ARSE,TMEM184B,RNF14,SEC14L5,RCAN1,RASGRP1,ZNF274,GCK,CSDC2,PPARGC1A,PTPRT,NEGR1,IDH3A,KIT,P2RX7,PLXNB1,MINDY2,KANSL1,RMI1,BDP1,SPART,USP22,NACC2,TBC1D15,ZNF74,DPYSL5,URM1" MicroRNA hsa-miR-4716-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-08 5.68E-05 1.62E-08 1.49E-07 24 167 "RNF157,SORCS2,EVI5L,DUSP9,EIF4G1,AFF2,CELF1,GLUL,MPP2,NBL1,CCSER2,BDNF-AS,IQSEC3,PRRT2,SETD5,EMID1,SARS,SHMT2,NMNAT2,ERC1,SSTR1,ZNF34,THRA,ITM2C" MicroRNA hsa-miR-151-5p:mirSVR_highEffct hsa-miR-151-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-08 5.70E-05 1.62E-08 1.49E-07 21 130 "RALGAPA1,FAM131A,NRP2,CACNA1G,KALRN,PTBP2,IST1,APH1A,RGS17,EPHB1,SRRM1,ERAP1,ZNF638,NME9,MEST,VSTM2L,PRODH,RASGRF2,SNAP25,DNMBP,CCDC14" MicroRNA hsa-miR-133a-3p:Functional MTI Functional MTI miRTarbase 1.02E-08 5.70E-05 1.62E-08 1.49E-07 21 130 "HCN2,ZFP28,HAPLN1,IP6K1,EGFR,ERBB2,PDLIM5,IGF1,RBPJ,IBA57,ITPKB,KCNH2,PKM,ZMAT4,PRRT2,RGS3,EMID1,MEG3,ZEB1,TPM1,NR2C2" MicroRNA hsa-miR-886-5p:mirSVR_highEffct hsa-miR-886-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-08 6.18E-05 1.76E-08 1.62E-07 15 66 "CACNA2D1,MTMR7,IQCK,DNAH9,SYT3,CAMKK2,NSG1,GAREM2,KCTD6,NTRK2,MTMR10,ATAT1,CCDC92,TUBB1,ATP6V0E2" MicroRNA hsa-miR-1255a:PITA hsa-miR-1255a:PITA_TOP PITA 1.13E-08 6.33E-05 1.80E-08 1.66E-07 17 86 "TAOK1,SPOP,NCOA1,CAMK2G,RUNX1T1,MYRIP,MFAP3L,FOXO3,BACH2,MAP2,PPP3CA,NLGN1,CAMTA1,RPGRIP1L,CELF4,REEP1,RNF146" MicroRNA hsa-miR-1255b:PITA hsa-miR-1255b:PITA_TOP PITA 1.13E-08 6.33E-05 1.80E-08 1.66E-07 17 86 "TAOK1,SPOP,NCOA1,CAMK2G,RUNX1T1,MYRIP,MFAP3L,FOXO3,BACH2,MAP2,PPP3CA,NLGN1,CAMTA1,RPGRIP1L,CELF4,REEP1,RNF146" MicroRNA hsa-miR-6893-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-08 6.76E-05 1.92E-08 1.77E-07 18 97 "SFMBT2,SEMA4G,GPR146,DST,CACNA1A,BAG4,WDPCP,IRAK4,AFF2,SRCAP,KIAA1958,KCNN1,KCTD15,CYB561D1,SCN7A,PEAR1,NFASC,DHX33" MicroRNA hsa-miR-6771-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-08 7.21E-05 2.04E-08 1.88E-07 24 169 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,APAF1,ADGRB2,IPCEF1,TMEM170A,RASA4,MRNIP,VPS26C,ZNF589,MTHFD2,BVES,QDPR,GSTCD,PTGR2,SEPHS1,FAM208A,CBX5,TBC1D15,ZNF28,TFIP11" MicroRNA hsa-miR-548a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-08 7.21E-05 2.04E-08 1.88E-07 24 169 "XKR4,PTCHD1,PHF12,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,STARD3NL,SCML2,SUCO,RNPS1,SCIN,KANSL1,GRAMD1C,DIRAS2,TMLHE,TUBB2A,EML6,SMARCAD1,NHSL1" MicroRNA hsa-miR-99a:PITA hsa-miR-99a:PITA_TOP PITA 1.29E-08 7.21E-05 2.04E-08 1.88E-07 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-100:PITA hsa-miR-100:PITA_TOP PITA 1.29E-08 7.21E-05 2.04E-08 1.88E-07 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-99b:PITA hsa-miR-99b:PITA_TOP PITA 1.29E-08 7.21E-05 2.04E-08 1.88E-07 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-08 7.33E-05 2.08E-08 1.91E-07 20 120 "DST,SYNJ2,DGKI,SRSF11,FBXO7,ZBED3,PCLO,MBP,PCDH9,PKD1,SNX10,PLEC,POLG,KANSL1,ROGDI,KLHL11,SPP1,USP22,ZNF225,STOX2" MicroRNA hsa-miR-7152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-08 7.33E-05 2.08E-08 1.91E-07 20 120 "ADD1,TNRC6C,PRX,THSD7A,LRRFIP1,PITPNM3,TM9SF4,IRAK4,DLC1,UFM1,PDLIM5,LILRA2,KPNA5,MEIS1,MTRF1L,RCOR3,SP4,CLSTN2,EXOC7,ZNF138" MicroRNA hsa-miR-1296-5p:Functional MTI Functional MTI miRTarbase 1.31E-08 7.33E-05 2.08E-08 1.91E-07 20 120 "BRAP,MTUS1,TXNDC16,APPL1,DCTN1,ERBB2,ZNF549,RNPS1,UBE2QL1,IPO5,LIFR,TBC1D25,POLR2F,SH3TC2,ZMAT4,NFASC,MPRIP,TMPO,ANKRD24,AAAS" MicroRNA hsa-miR-505-3p:Functional MTI Functional MTI miRTarbase 1.34E-08 7.48E-05 2.12E-08 1.95E-07 28 223 "TMEM132B,LTBP4,TNRC6C,PRC1,ZNF445,CSF1,SOCS5,RIMS4,PDE4DIP,FIS1,TUBB3,STAMBP,KCNMB4,PRRC2B,FUT10,NEGR1,IGF1,LIMS1,NPTX1,POLG,SALL1,TET1,SOX11,TAF9,TP53BP1,TUBB2A,PRDM10,HNRNPA3" MicroRNA "TCTGATA,MIR-361:MSigDB" "TCTGATA,MIR-361:MSigDB" MSigDB 1.36E-08 7.60E-05 2.15E-08 1.98E-07 17 87 "DPP10,MAGI1,QKI,ARMC8,CALCRL,GPHN,RRAGB,AFF2,LRP1B,MXI1,PCDH9,PDE4B,ZNF655,SCAF8,STAU1,ZFPM2,WNT7A" MicroRNA "GGCAGTG,MIR-324-3P:MSigDB" "GGCAGTG,MIR-324-3P:MSigDB" MSigDB 1.36E-08 7.60E-05 2.15E-08 1.98E-07 17 87 "PHF12,CHRD,FOXN3,DMTF1,EDNRA,EIF4G1,ING4,CIT,MBP,MEIS1,GIT1,SEMA5B,ZNF655,PRKACB,PBRM1,SHC4,FXR1" MicroRNA hsa-miR-1273:mirSVR_highEffct hsa-miR-1273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-08 7.76E-05 2.20E-08 2.02E-07 26 196 "SFMBT2,ARHGEF6,ERC2,ABCC5,SUGP2,PAN3,ZNF678,KCNJ16,ZNF667-AS1,MEF2C,MEIS1,NF1,NRCAM,PDE4B,XRN1,FIGN,NUDT11,PBRM1,MYO16,DOK5,DDN,DIP2A,CAMTA1,SLC44A1,HEY1,CPNE4" MicroRNA hsa-miR-671-5p:Functional MTI Functional MTI miRTarbase 1.41E-08 7.90E-05 2.23E-08 2.06E-07 23 157 "OGT,ATP1B3,ATP2A2,CDR1,EPB41,ZNF391,ZNF585B,FOXO3,USP21,CYP46A1,ZNF678,NACA,R3HDM2,PKNOX2,SSPO,SEPT3,SATB2,TRIM2,SMUG1,TSN,BCL2L13,FBXO36,SPATA13" MicroRNA hsa-miR-151a-3p:TargetScan hsa-miR-151a-3p TargetScan 1.43E-08 8.00E-05 2.26E-08 2.08E-07 16 77 "ATP2A2,PLXNA4,PPP1R16B,ELMO1,DLC1,CHL1,GHR,PDE3A,CEP41,PKIA,FIGN,CLASP2,NPL,NAV3,FXR1,GAN" MicroRNA hsa-miR-223-3p:Functional MTI Functional MTI miRTarbase 1.43E-08 8.01E-05 2.26E-08 2.08E-07 18 98 "PTBP2,SCARB1,FOXO3,IL6ST,STMN1,LMO2,MEF2C,NFIX,NOVA2,PAX6,ABCB1,MTRF1L,FBXW7,NMNAT2,PRRC2C,TAL1,ZEB1,NLRP3" MicroRNA hsa-miR-1289:PITA hsa-miR-1289:PITA_TOP PITA 1.43E-08 8.01E-05 2.26E-08 2.08E-07 18 98 "CALM1,ZNF385A,PHC2,APH1A,TMEM35A,TTBK1,PLPP7,XRN1,KCTD15,STRN3,ATXN7,SCP2,FUZ,SOX11,CLASP2,DOCK9,ZIC2,GDPD5" MicroRNA hsa-miR-6837-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-08 8.01E-05 2.26E-08 2.08E-07 18 98 "KCTD16,TAOK1,PHF12,GAS7,STOML1,SUSD5,DOCK4,CENPL,NR1D2,STARD3NL,CELF1,SYTL4,SCN8A,ZC3H13,SATB2,CYB561A3,ZNF138,ZNF195" MicroRNA hsa-miR-7154-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-08 8.28E-05 2.34E-08 2.15E-07 14 58 "BBS2,CA8,LONRF2,CPS1,EDIL3,EDN1,TENM1,PLEKHA1,MBNL1,SH3TC2,CHD9,NBPF1,ERBIN,KLHL4" MicroRNA hsa-miR-4680-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-08 8.41E-05 2.37E-08 2.19E-07 22 145 "C2CD2,RNF165,KCNN3,CREG2,EFHB,TBC1D25,PDPK1,TMOD2,CCSER2,PIGG,NCR3LG1,ZIK1,HSPA4L,NUBPL,PEX26,ANKRD36,SSTR2,STAC2,KLHL7,SLC19A3,ZNF708,GAN" MicroRNA hsa-miR-4645-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-08 8.41E-05 2.37E-08 2.19E-07 22 145 "LTBP4,APAF1,DNAH17,DDR1,NUMBL,ANKMY1,POLR1B,C15orf41,FUT10,RNF165,IRAK3,CREG2,QDPR,ELP2,PEAR1,SH3BP2,R3HDM2,PEX26,TRIM67,ARC,SLC37A2,AMZ1" MicroRNA hsa-miR-3925-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-08 8.63E-05 2.44E-08 2.24E-07 21 133 "NCKAP5,TNRC6C,SOCS6,FAM131B,TMCC2,NR1D2,CELF5,SOWAHA,KIAA1755,ZNF678,CREG2,ELP2,NCBP3,RADIL,ZNF667,SNAP25,APOM,NSFL1C,ZNF138,WNK2,SPATA13" MicroRNA hsa-miR-4646-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-08 8.63E-05 2.44E-08 2.24E-07 21 133 "RGS6,ASB3,VPS26C,AMOTL2,MTHFD2,CRCP,GLUL,POLL,LILRA2,BVES,NEGR1,KCTD15,KIAA0895L,PEX26,UNC5B,NFASC,NXT2,HIF3A,CBX5,BHLHB9,ZBTB38" MicroRNA hsa-miR-1233-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-08 8.64E-05 2.44E-08 2.24E-07 26 197 "PHF12,LONRF2,SUMF2,CRY2,FAM131B,DCAF8,IP6K1,E2F6,PHC2,TMTC1,AHDC1,IRAK3,NEGR1,KCNK3,PFKFB3,PMP22,PPARA,KLHDC8A,MRAS,SLC11A1,CAMTA2,RPRM,UBTF,KLC2,CIAPIN1,WNK2" MicroRNA hsa-miR-651-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-08 9.11E-05 2.57E-08 2.36E-07 28 225 "OSBPL6,OGT,IGDCC4,ATP2A2,CRY2,SOCS5,PUM1,DCAF8,LONRF1,SPATA2,CHRDL1,TVP23A,PRRC2B,TTYH2,MKLN1,PDPK1,PTPRB,LGI3,COA1,TMCC1,IQSEC2,SEPT3,SLC44A1,UBC,CLDND1,ZXDA,ITM2C,SPATA13" MicroRNA hsa-miR-588:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-08 9.11E-05 2.57E-08 2.36E-07 28 225 "TAOK1,C6orf89,AKAP6,LRIG1,CSNK1E,MYADM,KIAA0586,DBT,COQ7,TRMO,CRCP,DDX19B,ZNF678,CYP27C1,MYO6,FBXW7,SGSM1,PTGR2,SATB1,PEX26,FAM126B,LHPP,SSTR2,ALG1,AGTPBP1,ZNF70,URM1,GAN" MicroRNA hsa-miR-1264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-08 9.18E-05 2.59E-08 2.38E-07 19 110 "KIAA1211,SEMA7A,TNRC6C,ZNF555,QKI,EDIL3,RGS17,DCTN4,POLR1B,IP6K2,ZBED3,GATM,CHIC1,MYO6,PCDH9,RFX3,EXD2,ANKRD6,FXR1" MicroRNA hsa-miR-3678-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-08 9.18E-05 2.59E-08 2.38E-07 19 110 "IGDCC4,EPS15L1,CPS1,APH1A,SLC43A2,GABRB3,COPS8,TNRC6A,RNF165,ATOH8,PADI2,ZNF678,IPO5,TMEM104,SH3TC2,SLC25A36,GSTCD,IQCE,GAN" MicroRNA hsa-miR-6730-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-08 9.54E-05 2.69E-08 2.48E-07 15 68 "CCNT1,PPP1R16B,KIAA0408,MTX3,RPS6KL1,ERBB2,SMC2,METTL21A,LSAMP,CHIC1,MPP2,ALDH1L2,PKD1,OXR1,TMEM200C" MicroRNA "CAGGGTC,MIR-504:MSigDB" "CAGGGTC,MIR-504:MSigDB" MSigDB 1.74E-08 9.73E-05 2.74E-08 2.52E-07 16 78 "ZNF608,PCDH10,OGT,CHRD,CAMK2G,USP2,CNTFR,SUGP2,EPB41,BAIAP2,PCDH17,TMEM121B,BACH2,NFIX,MCMBP,SMPD3" MicroRNA hsa-miR-7108-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-08 9.73E-05 2.74E-08 2.52E-07 16 78 "MARCH4,LRFN1,MARK4,LDHD,CBARP,TOGARAM2,ZNF385A,NCOR2,PITPNM3,KIAA1958,KIFC3,XRRA1,MSR1,SZT2,NAT16,SSBP2" MicroRNA hsa-miR-944:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-08 9.80E-05 2.76E-08 2.54E-07 20 122 "FMNL2,SLC24A4,HECW2,ATP2A2,BACH1,SRSF11,DPYSL2,DNAJB6,GATM,SNRK,SPDL1,SETD5,CHD9,BTBD3,LIMCH1,BDP1,ZMAT3,UBE3A,EVI5,FXR1" MicroRNA hsa-miR-2355-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-08 1.00E-04 2.82E-08 2.60E-07 25 185 "RALGAPA1,TAOK1,GYG2,CACNA1A,LURAP1,HINFP,CCDC144A,FAM13A,APH1A,UFM1,ST6GALNAC3,NEURL4,ZNF638,BACH2,POU6F1,PPP2R5E,GTDC1,PTGR2,ZFP30,ZFP1,ANKRD36,ZNF415,ADAMTS17,DOK6,ZNF138" MicroRNA hsa-miR-99b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-08 1.03E-04 2.89E-08 2.66E-07 13 50 "PUM1,KIAA0319,GSTM5,MAP4,MMP16,PPP5C,ZNF793,KIRREL1,DZIP1,ZNF621,AGTPBP1,CCDC14,WIPF1" MicroRNA "GTGTCAA,MIR-514:MSigDB" "GTGTCAA,MIR-514:MSigDB" MSigDB 1.88E-08 1.05E-04 2.95E-08 2.72E-07 14 59 "TAOK2,NRXN3,GRM8,NCOA7,PTPRG,BAALC,ARHGEF9,TAL1,TRIM2,TCF12,EIF4ENIF1,ZIC1,NAV3,ST8SIA2" MicroRNA hsa-miR-431-5p:TargetScan hsa-miR-431-5p TargetScan 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "PTCHD1,DPY19L3,DST,NRXN3,CLTC,NRG2,AKAP12,HIPK3,RNFT2,MEIS1,CCSER2,DIRAS2,ALG9,ARHGEF40,CCDC88A,PPIL6,LYPD6,LAMP5,NETO1" MicroRNA hsa-miR-409-3p:Functional MTI Functional MTI miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "XKR4,C1QTNF3,MTMR7,FOXN3,GUCD1,GCK,MALT1,TNRC6A,GNAL,DIDO1,MINDY2,RDX,RNASEL,ZFHX4,CPEB4,KDM4C,ZEB1,ZMAT3,TMPO" MicroRNA hsa-miR-208b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "PCDH19,CDH2,LRIG1,SOCS5,SYNCRIP,UFM1,SRRM4,MSTN,SLC2A6,RBPJ,SLC35G1,MTRF1L,CEP97,ATP8B4,KIF21A,SNAP25,LRRC8A,JMJD1C,ZDHHC20" MicroRNA hsa-miR-4650-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "MTUS1,DYNLL1,SLC2A11,CRY2,DNAL1,E2F6,EIF4G2,TUBD1,POLL,TDRKH,RABL2A,DDX19B,IL6ST,MTRF1L,GDPD1,FIGN,CSRNP3,SMARCAD1,FXR1" MicroRNA hsa-miR-382-5p:Functional MTI Functional MTI miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "SYT13,SYNJ2,CALM1,CLTC,RBM39,KLHL3,YAF2,COPS4,MTHFD2,NEXMIF,PFKFB2,FNIP1,SLC6A8,MTCL1,DICER1,ZKSCAN5,XPO1,PLSCR4,NETO2" MicroRNA hsa-miR-4786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "SFMBT2,ATP2A2,DGKI,HEPH,TOM1,FSD1L,ZNF391,FOXO3,ATP13A4,CYP46A1,GPER1,ZNF426,NCBP3,R3HDM2,MPRIP,SEPT3,ANKRD24,ZNF225,FBXO36" MicroRNA hsa-miR-370-3p:Functional MTI Functional MTI miRTarbase 1.91E-08 1.07E-04 3.00E-08 2.77E-07 19 111 "SFMBT2,SEMA4G,GPR146,DST,CACNA1A,BAG4,WDPCP,IRAK4,AFF2,SRCAP,KIAA1958,KCNN1,NF1,KCTD15,CYB561D1,SCN7A,PEAR1,NFASC,DHX33" MicroRNA hsa-miR-3171:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-08 1.13E-04 3.17E-08 2.92E-07 12 42 "ESYT2,PHF12,ATP1B3,ATP2A2,SRSF11,COL4A5,ANKRD44,MMP16,PDE3A,CHD9,ZHX3,FRYL" MicroRNA hsa-miR-1304-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-08 1.13E-04 3.17E-08 2.92E-07 21 135 "KLHL32,CEP126,LTBP4,CACNA1B,CCNT1,C1orf52,NRXN3,RIMS4,ABCC5,PCYOX1,GSN,ZNF491,MMP17,PDE3A,MSANTD2,SLC2A5,NMNAT2,FAM208A,CBX5,TNS1,URM1" MicroRNA hsa-miR-7154-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-08 1.13E-04 3.17E-08 2.92E-07 21 135 "CASKIN1,ARHGDIA,LDB2,CS,CSF1,ZBTB45,NEGR1,KSR2,PKM,SMIM7,PLXNB1,POLG,SOX11,PEG10,DBNDD2,THRA,ERCC6L2,WBP2,WRN,KLC2,ZNF17" MicroRNA hsa-miR-136-5p:Functional MTI Functional MTI miRTarbase 2.03E-08 1.14E-04 3.18E-08 2.93E-07 23 160 "MADD,EIF4G3,DST,NRG2,C2CD2,SEC14L5,GAPVD1,TMEM170A,FSD1L,SLC37A3,GABRG2,DISC1,PCLO,RABL2A,IFI16,FNIP1,NUBPL,FAM214B,SNAP25,ZNF621,ITPRID2,RPL7L1,SLC38A1" MicroRNA hsa-miR-361-5p:Functional MTI Functional MTI miRTarbase 2.03E-08 1.14E-04 3.18E-08 2.93E-07 23 160 "RALGAPA1,ZBTB10,BACH1,VXN,DCTN1,JKAMP,MSANTD4,TNRC6A,HSF2,AFF1,ZNF92,PDE3A,PLCL1,SEMA6D,HSPA4L,SGK1,USP22,ZMAT3,TP53BP1,WBP2,MTCH1,ZNF154,TFIP11" MicroRNA hsa-miR-30d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.03E-08 1.14E-04 3.18E-08 2.93E-07 23 160 "CDK13,ENTPD4,MAML1,YTHDC1,FAM107B,EIF1,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,KCTD6,EPB41L4B,SH3TC2,CCDC25,SCP2,GALNT10,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2" MicroRNA hsa-miR-937:mirSVR_lowEffct hsa-miR-937:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.03E-08 1.14E-04 3.18E-08 2.93E-07 23 160 "SUGT1P4-STRA6LP-CCDC180,GPR146,LHX2,CRMP1,POM121,SLC29A4,SLC43A2,FCGR3A,TXNL4A,STMN2,PACSIN2,DISP2,MITF,CCDC13,ARFGAP1,KDM4C,NPDC1,ZFP41,POLR3H,STOX2,TMEM178A,SEMA3B,CASC15" MicroRNA hsa-miR-7156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-08 1.18E-04 3.30E-08 3.04E-07 16 79 "SPOP,C1orf52,USP6NL,YTHDC1,YAF2,ERBB2,STAMBP,TUBGCP4,TNRC6A,ATOH8,NCKAP1L,IGF1,PDE1B,ZNF793,DNAJC9,TRPS1" MicroRNA hsa-miR-3614-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-08 1.22E-04 3.41E-08 3.14E-07 28 228 "AS3MT,BRAP,HACE1,SFMBT2,ZNF583,ISPD,FOXN3,SUSD5,USP6NL,SGSM2,CELSR3,MRNIP,SEPT9,GPR75,ADAP1,KAT7,SLC11A2,CCSER2,PRKCB,BDNF-AS,ZNF844,CEP97,MYO18A,CDK19,PCDHA6,BHLHB9,EVI5,JMJD1C" MicroRNA hsa-miR-188-5p:Non-Functional MTI Non-Functional MTI miRTarbase 2.23E-08 1.25E-04 3.49E-08 3.21E-07 19 112 "SPOP,AQP6,CACNA1A,VXN,SLC16A4,SEC31B,ELMSAN1,ABCC5,TMTC1,PLEKHA1,ITGA7,KLHL23,MBNL1,PCDH9,CEP97,GTDC1,UBR7,GALNT10,KAT6A" MicroRNA hsa-miR-449a:Functional MTI Functional MTI miRTarbase 2.29E-08 1.28E-04 3.58E-08 3.30E-07 23 161 "PKP4,ZMYM4,EVI5L,FOXN3,MRNIP,APOPT1,POLL,FICD,DDX19B,MAP4,MKLN1,MYCN,CNOT4,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,SIRT1,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-32-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-08 1.30E-04 3.64E-08 3.35E-07 20 124 "CC2D2A,USP37,FAM169A,MYADM,NCALD,MED12L,CELF1,PPARGC1A,KIAA1958,RBPJ,PAXBP1,NCOA7,GPSM2,WDR37,BTBD3,PEG10,VLDLR,MAP3K12,HNRNPA3,ZDHHC20" MicroRNA hsa-miR-525-3p:mirSVR_highEffct hsa-miR-525-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-08 1.30E-04 3.64E-08 3.35E-07 20 124 "PCDH10,AMPD3,NUMB,QKI,GOLT1B,EBF1,FCGRT,ATP2C1,COPS8,AQP11,NF1,NTRK3,GTDC1,KIAA0895L,HSD11B1L,SH3BGR,ZC3H13,DDN,ADGRL3,MTMR14" MicroRNA hsa-miR-4292:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-08 1.30E-04 3.64E-08 3.35E-07 20 124 "ZNF445,EPS15L1,UBXN2A,IP6K1,EIF5,IRAK4,ANKMY1,CELF1,SEPT9,ITPKB,MAT2A,PKD1,MTMR10,IQSEC3,PRRT2,HES6,PEX26,DIP2A,EXOC7,KAT6A" MicroRNA hsa-miR-1471:mirSVR_lowEffct hsa-miR-1471:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-08 1.31E-04 3.66E-08 3.37E-07 18 101 "METAP1D,CSF2RA,RHOBTB1,DLX1,SLC29A4,TOM1,EGFR,C3orf18,SRRM1,SERP2,CACFD1,IGF1,KCNN3,MYO7A,FAM66C,ZSWIM8,PDLIM2,TSC1" MicroRNA hsa-miR-644:PITA hsa-miR-644:PITA_TOP PITA 2.34E-08 1.31E-04 3.66E-08 3.37E-07 18 101 "ATP1A1,DMTF1,EPB41L2,SYNCRIP,FOXO3,TNRC6A,GRIN2D,SMAP1,NEFH,NF1,GNG2,MINDY2,ROBO2,STAC2,TCF4,TPM1,NR2C2,NAV3" MicroRNA hsa-miR-582-5p:Functional MTI Functional MTI miRTarbase 2.50E-08 1.40E-04 3.90E-08 3.59E-07 22 149 "TRMT9B,PDE4DIP,ZC3H11A,EIF4G2,FLT1,TNRC6A,DIDO1,DDX19B,ZDHHC15,ZNF678,KCNB1,MYCN,SLC11A2,PPP2R5E,QDPR,PGBD4,LRRK2,DICER1,TSN,RPL7L1,CFAP298,GAN" MicroRNA hsa-miR-6757-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-08 1.42E-04 3.97E-08 3.66E-07 16 80 "ESYT2,OGT,ATP1B3,DPY19L3,C1orf52,IP6K1,CPEB2,STAMBP,CELF1,SRRM4,STMN1,ZNF793,ZNF621,TBCEL,ZNF781,DHX33" MicroRNA hsa-miR-4273:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-08 1.42E-04 3.97E-08 3.66E-07 16 80 "SPOP,C1orf52,USP6NL,YTHDC1,YAF2,ERBB2,STAMBP,TUBGCP4,TNRC6A,ATOH8,NCKAP1L,IGF1,PDE1B,ZNF793,DNAJC9,TRPS1" MicroRNA hsa-miR-8076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-08 1.42E-04 3.97E-08 3.66E-07 16 80 "BACH1,RUNX1T1,CCNT1,CDC25B,DNAL1,MSANTD4,MPP6,BVES,HSF2,PTPRD,SATB1,TROVE2,MPRIP,ZC3H4,ARL10,SLC38A1" MicroRNA hsa-miR-216a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-08 1.43E-04 4.00E-08 3.68E-07 29 244 "ADD1,FZD9,TAOK1,CCNT1,ZNF385A,RGS6,LONRF1,LIN54,SEC16A,NR1D2,EIF5,POLR1B,SUCO,TPPP,KAT7,SLC6A17,LIFR,MKLN1,PDE3A,PKD1,SDK2,RETREG2,R3HDM2,ZFP1,PEG10,TROVE2,MPRIP,FRYL,WRN" MicroRNA hsa-miR-3681-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-08 1.43E-04 4.00E-08 3.68E-07 29 244 "ADD1,FZD9,TAOK1,CCNT1,ZNF385A,RGS6,LONRF1,LIN54,SEC16A,NR1D2,EIF5,POLR1B,SUCO,TPPP,KAT7,SLC6A17,LIFR,MKLN1,PDE3A,PKD1,SDK2,RETREG2,R3HDM2,ZFP1,PEG10,TROVE2,MPRIP,FRYL,WRN" MicroRNA hsa-miR-6847-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.58E-08 1.44E-04 4.02E-08 3.70E-07 23 162 "INTS2,CARNS1,ATP1B3,MTMR3,DDR1,POM121,ANKRD46,MTSS1L,AMOTL2,IDH3A,NKD1,MPP2,TMOD2,PLEC,PPP2R5E,ELP2,GALNT10,MYO18A,SLC8A1,NEK4,SLC37A2,CIAPIN1,GAN" MicroRNA hsa-miR-7852-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.59E-08 1.45E-04 4.04E-08 3.72E-07 15 70 "FZD9,PCDH10,ANKRD46,GORAB,SESN1,TNRC6A,IL6ST,ZNF678,KIF5A,MYO5A,RDX,FIGN,PRIMA1,MCMBP,BTBD3" MicroRNA hsa-miR-346:PITA hsa-miR-346:PITA_TOP PITA 2.59E-08 1.45E-04 4.04E-08 3.72E-07 15 70 "FAM131A,RBM39,RIMS2,DGKG,MYEF2,PRRC2B,ADAMTS6,MBNL1,PKIA,RDX,SLC25A36,PEG10,CCDC136,ZIC1,HRASLS" MicroRNA "CCTGAGT,MIR-510:MSigDB" "CCTGAGT,MIR-510:MSigDB" MSigDB 2.71E-08 1.52E-04 4.22E-08 3.89E-07 12 43 "LRFN2,CAMK2G,ING4,EPHB1,IP6K2,GGT7,HLF,NOVA1,ZNF655,PPP2R5E,RORB,ST8SIA2" MicroRNA hsa-miR-6805-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-08 1.54E-04 4.28E-08 3.94E-07 18 102 "NDRG3,CASKIN1,EVI5L,ZNF385A,SPATA2,ABCC5,EIF1,AHDC1,MMP17,MSI1,PDE4A,FXYD1,SHMT2,NMNAT2,ERC1,THRA,MGAT5B,CIAPIN1" MicroRNA hsa-miR-126:mirSVR_lowEffct hsa-miR-126:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-08 1.54E-04 4.28E-08 3.94E-07 17 91 "ARNTL,SRSF11,CHN2,ARMCX1,FAM198B,ERAP1,TNRC6A,GRIA2,PCDH9,RORB,CCDC102B,GALNT10,PPP4R3A,PDZRN3,TP53BP2,TSC1,ADAMTS9" MicroRNA hsa-miR-576-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-08 1.54E-04 4.28E-08 3.94E-07 17 91 "PHF12,SRSF11,LETMD1,HINFP,DLC1,SCARA3,FUT9,MTHFD2,AGFG1,KPNA5,SDK2,PPP2R5E,SGK1,FAM102A,ZNF708,ZNF24,STOX2" MicroRNA hsa-miR-2052:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-08 1.54E-04 4.28E-08 3.94E-07 17 91 "LONRF1,DMD,CELSR3,TNRC6A,CBX1,RASSF8,IL6R,MAT2A,ZSCAN2,FBXW7,CHD9,PEX26,ZEB1,FAM200B,STXBP4,ZNF28,ZXDA" MicroRNA hsa-miR-4524b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-08 1.55E-04 4.31E-08 3.96E-07 25 189 "TAOK1,TRMT9B,CASK,MTMR3,CA8,CCNT1,SOCS5,YTHDC1,DMTF1,PLEKHA1,MYO5A,OCRL,PIK3R1,PSAT1,CNNM2,PTPRD,ZFHX4,ZC3H14,SALL1,ATXN2,KANK1,ZMAT3,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-4524a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-08 1.55E-04 4.31E-08 3.96E-07 25 189 "TAOK1,TRMT9B,CASK,MTMR3,CA8,CCNT1,SOCS5,YTHDC1,DMTF1,PLEKHA1,MYO5A,OCRL,PIK3R1,PSAT1,CNNM2,PTPRD,ZFHX4,ZC3H14,SALL1,ATXN2,KANK1,ZMAT3,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-3619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-08 1.58E-04 4.39E-08 4.05E-07 22 150 "ELFN2,CASKIN1,SFMBT2,ZBTB10,LDLRAD4,TBPL1,CS,SOCS5,RUBCN,HEYL,FGFR1,FAM49B,MTHFD2,GNAL,PPM1L,KCTD15,CNNM2,CPEB4,ERC1,RPL7L1,BCL2L13,GDPD5" MicroRNA hsa-miR-4701-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-08 1.62E-04 4.51E-08 4.15E-07 23 163 "TXNDC16,TAOK1,CDC14B,ZNF555,SOCS5,MTX3,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,UNC5B,MCF2L2,SSTR2,NACC2,SSBP2,USP1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-6736-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-08 1.62E-04 4.51E-08 4.15E-07 23 163 "TXNDC16,TAOK1,CDC14B,ZNF555,SOCS5,MTX3,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,UNC5B,MCF2L2,SSTR2,NACC2,SSBP2,USP1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-103b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.97E-08 1.66E-04 4.61E-08 4.25E-07 14 61 "CA12,CRY2,LIN54,DMTF1,SPECC1,GSN,MSL1,PPM1L,GPSM2,GLDN,NCBP3,SPART,KLHL7,RPL7L1" MicroRNA hsa-miR-6752-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-08 1.72E-04 4.77E-08 4.40E-07 20 126 "RNF150,SORCS2,SEMA4G,LDLRAD4,CACNA1A,AKAP5,RTTN,CRY2,SRCAP,TXNL4A,RAB40B,GPD1,FAM107A,KCNQ3,MAN2A2,NFIX,KCTD15,DPF2,GALNT10,GALNT17" MicroRNA hsa-miR-3123:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-08 1.72E-04 4.77E-08 4.40E-07 20 126 "BCAS1,IGDCC4,CALM1,BAG4,TM9SF4,RASA4,AMOTL2,SLC37A3,ST6GALNAC3,CRCP,COPS8,TNRC6A,ZC3H12B,ZIK1,NWD1,TBCEL,NR2E1,SPIRE1,PARP11,FRMD6" MicroRNA hsa-miR-4465:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-08 1.72E-04 4.78E-08 4.40E-07 25 190 "MTA3,ZNF608,PDE4DIP,KIAA0408,ZBTB24,SACS,RGS17,FKTN,TNRC6A,ZBTB45,EID2B,MAT2A,BLOC1S2,ZNF426,PSAT1,NWD1,SLC25A36,ARMH4,FAM126B,DIP2A,ALG1,AGTPBP1,ASXL3,SSBP2,UBE2H" MicroRNA "TCCAGAT,MIR-516-5P:MSigDB" "TCCAGAT,MIR-516-5P:MSigDB" MSigDB 3.22E-08 1.80E-04 4.99E-08 4.60E-07 18 103 "GPRASP2,NCOA1,ATP2A2,BCL7A,SPAG9,NUMBL,CSF1,DBN1,RASGRP2,EPHB1,SEMA4D,ADAMTS6,NCOA7,MMP16,FHOD3,IQSEC2,LRRC8A,PHTF2" MicroRNA hsa-miR-641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-08 1.80E-04 4.99E-08 4.60E-07 18 103 "KLHL32,AXIN2,THSD7A,LIN54,GOLT1B,DLC1,IQGAP2,P2RY1,MAPK10,FIGN,NBPF1,ANKRD36,LIMCH1,SNAP25,POGZ,SLC35G2,ZNF106,CLDND1" MicroRNA hsa-miR-4269:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-08 1.91E-04 5.30E-08 4.88E-07 21 139 "APAF1,BTK,NUMBL,DNAH9,TUBD1,IGSF6,TMEM132C,FDFT1,POLR1B,TXNL4A,ZIC5,RMI1,SBF1,SH3BP2,R3HDM2,UNC5B,GALNT17,TRPS1,TSN,RPL7L1,SIGLEC10" MicroRNA hsa-miR-4262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-08 1.91E-04 5.30E-08 4.88E-07 21 139 "HFM1,DCAF4,FAM13A,IQCG,ZDHHC15,NCOA7,PPP2R5E,ZNF844,ATXN7,SCN8A,CHD9,ZNF667,ZNF415,TMCC1,SPP1,UNC5B,SLC35G2,TUBB2A,ZNF781,ZNF23,SPIRE1" MicroRNA hsa-miR-611:PITA hsa-miR-611:PITA_TOP PITA 3.46E-08 1.94E-04 5.36E-08 4.94E-07 9 22 "XKR4,PICK1,APH1A,EIF4G1,NFIX,GTDC1,SYN1,RIMBP2,TRPS1" MicroRNA hsa-miR-99a:mirSVR_highEffct hsa-miR-99a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.47E-08 1.94E-04 5.38E-08 4.95E-07 19 115 "CNTFR,SLC35F1,HS3ST2,SLC29A4,FGFR3,KIAA1841,TUBGCP4,MIER3,MBNL1,CLDN11,PPP3CA,EPDR1,ERI2,AP1AR,CCDC88A,PRRC2C,SLC44A1,ZNF19,WNK3" MicroRNA hsa-miR-4481:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-08 1.97E-04 5.46E-08 5.03E-07 20 127 "DNAH17,SEC24C,ZC3H11A,ING4,GLUL,MIER3,TJAP1,IBA57,PFKFB2,PKM,MRPS18A,KIAA0895L,NCBP3,SBF1,PEX26,TPCN2,SLC19A3,NSD1,RPRM,UBTF" MicroRNA hsa-miR-3692-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-08 1.97E-04 5.46E-08 5.03E-07 20 127 "SORCS2,THSD7A,QKI,TOGARAM2,GAPVD1,TIAM2,CPEB2,FDFT1,APOPT1,ZNF496,NCKAP1L,LIFR,MYO6,PLCL1,PRKACB,RXRA,ANKRD12,TPCN2,ZNF138,ZXDA" MicroRNA hsa-miR-6791-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-08 1.97E-04 5.46E-08 5.03E-07 20 127 "ZNF445,EPS15L1,UBXN2A,IP6K1,EIF5,IRAK4,ANKMY1,CELF1,SEPT9,ITPKB,MAT2A,PKD1,MTMR10,IQSEC3,PRRT2,HES6,PEX26,DIP2A,EXOC7,KAT6A" MicroRNA hsa-miR-7113-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-08 1.97E-04 5.46E-08 5.03E-07 26 205 "RNF150,BACH1,CACNA1A,CCNT1,QKI,AKAP5,RTTN,PITPNM3,CYBB,SPATA2,IRAK4,EMX2,UFM1,CELF1,SRRM4,ZNF638,SHISA6,KCNQ3,LSAMP,MBNL1,NOVA2,MTMR10,PTPRG,PEX26,DIP2A,IQCE" MicroRNA hsa-miR-761:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-08 2.02E-04 5.58E-08 5.14E-07 22 152 "ELFN2,CASKIN1,SFMBT2,ZBTB10,LDLRAD4,TBPL1,CS,SOCS5,RUBCN,HEYL,FGFR1,FAM49B,MTHFD2,GNAL,PPM1L,KCTD15,CNNM2,CPEB4,ERC1,RPL7L1,BCL2L13,GDPD5" MicroRNA hsa-miR-6793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-08 2.02E-04 5.58E-08 5.14E-07 22 152 "LRFN1,LGR5,CACNA1A,LURAP1,ELMO1,RASL10A,NEURL4,SRRM4,GLI2,ZNF638,RAB40B,GPD1,GSTM5,SLC6A17,KSR2,OPRL1,SKOR1,ZNF793,RBBP6,GTDC1,ADAMTS17,DOK6" MicroRNA hsa-miR-4795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-08 2.02E-04 5.58E-08 5.14E-07 22 152 "AK2,TAOK1,PHF12,DYNLL1,NRXN3,PHC2,C3orf18,FKTN,FOXO3,LILRA2,FICD,MYO5A,SLC25A23,ZNF426,SCN2B,CPEB4,DDN,TBCEL,ZNF106,KAT6B,UBTF,FXR1" MicroRNA hsa-miR-6847-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-08 2.02E-04 5.58E-08 5.14E-07 22 152 "PLEKHH1,ARHGDIA,CCPG1,AKAP5,PITPNM3,GREB1,DNAL1,SPECC1,CELF1,TRAF3IP2,MUM1,IGF1,KCNJ5,PEX2,SH3BP2,CNKSR2,INAVA,RPL7L1,ZNF711,ZNF17,SLC38A1,FBXO36" MicroRNA hsa-miR-5197-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-08 2.04E-04 5.65E-08 5.20E-07 23 165 "SLC24A4,TXNDC16,ASPA,DBT,PLEKHA1,POLR1B,SUCO,GPR75,KDM2B,LILRA2,HLF,IL6R,MBNL1,AFF1,NPTX2,PIGG,TMEM145,NWD1,MCMBP,PEG10,SSTR2,SLC35G2,VLDLR" MicroRNA hsa-miR-4314:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.76E-08 2.10E-04 5.81E-08 5.35E-07 18 104 "AP1M1,UBXN2A,RIPOR2,IP6K1,RASA4,VPS26C,MTHFD2,CRCP,GLUL,POLL,BVES,NEGR1,MPP2,KCNIP3,PEX26,MBD5,ZBTB38,DHX33" MicroRNA hsa-miR-147b:mirSVR_highEffct hsa-miR-147b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.76E-08 2.10E-04 5.81E-08 5.35E-07 18 104 "ADAM15,BTK,CBFA2T2,FBXL5,DTNB,AIFM3,KCNN2,BDNF-AS,KIF7,RORB,ZFP2,SEC14L1,FAM102A,SEPHS1,KIF13A,KAT6B,WIPF1,NDRG4" MicroRNA hsa-miR-6830-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.85E-08 2.16E-04 5.95E-08 5.48E-07 17 93 "TNRC6C,BAG4,PITPNM3,DPP6,FRY,PHF20L1,GATM,PCDH17,KAT7,RASSF8,NEGR1,KIAA1755,KCNN3,KSR2,GLIPR1L2,SNX10,ZNF711" MicroRNA hsa-miR-3934-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.85E-08 2.16E-04 5.95E-08 5.48E-07 17 93 "ABCF1,TBPL1,PPP1R16B,FBXL5,TNRC6A,POLL,ZIC5,GPR155,PPM1L,MYO5A,RDX,C12orf49,RMI1,ANKRD36,DDN,RPL7L1,PLSCR4" MicroRNA hsa-miR-586:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.85E-08 2.16E-04 5.95E-08 5.48E-07 17 93 "THSD7A,CALM1,C1orf52,TLR7,ACSL4,ZBED3,MMADHC,COPS8,LILRA2,ZIC5,ZNF678,GPR173,OXR1,DICER1,TNS1,RPL7L1,KCNK12" MicroRNA hsa-miR-5100:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-08 2.17E-04 5.98E-08 5.51E-07 15 72 "C1QTNF3,MATR3,EIF5,KATNAL1,SUCO,UFM1,CAMKK2,TNRC6A,ZBTB49,KCNN3,PCSK1,EPB41L4B,MINDY2,SH3TC2,SPATA13" MicroRNA hsa-miR-105*:mirSVR_highEffct hsa-miR-105*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.01E-08 2.24E-04 6.19E-08 5.70E-07 19 116 "SYN3,CLK4,NRP2,CNTFR,SRRM1,SYNCRIP,NELFCD,GRIN2D,GUCY1B1,MYCN,NEFH,ZDHHC8,HYDIN,ZSCAN32,RPGRIP1L,TTC3,RPRM,VLDLR,PRTFDC1" MicroRNA hsa-miR-4745-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-08 2.26E-04 6.22E-08 5.73E-07 20 128 "DNAH17,SEC24C,ZC3H11A,ING4,GLUL,MIER3,TJAP1,IBA57,PFKFB2,PKM,MRPS18A,KIAA0895L,NCBP3,SBF1,PEX26,TPCN2,SLC19A3,NSD1,RPRM,UBTF" MicroRNA hsa-miR-3120-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-08 2.26E-04 6.22E-08 5.73E-07 20 128 "MYRF,STARD3NL,DHX35,METTL21A,LIFR,SHC3,GPR137C,PDE4D,PRKACB,TRERF1,MPRIP,SYP,DNMBP,CRTC1,ASXL3,TUBB2A,RPL7L1,TBC1D15,NDRG4,SLC30A4" MicroRNA hsa-miR-328-3p:TargetScan hsa-miR-328-3p TargetScan 4.07E-08 2.28E-04 6.28E-08 5.78E-07 22 153 "ASIC1,FUBP1,HAP1,NRG2,DYNC1I1,HEYL,HPCAL4,ANKFY1,LYVE1,PADI2,NXPH3,KIF2A,MMP16,MN1,MXI1,SDK2,GTDC1,SCN2B,FAM214B,CCDC88A,KAT6B,POLR3H" MicroRNA hsa-miR-338-5p:Non-Functional MTI Non-Functional MTI miRTarbase 4.38E-08 2.45E-04 6.76E-08 6.22E-07 18 105 "XKR4,PTBP2,MATR3,GOLT1B,GOLGA7,RCAN2,CRCP,USP51,FIGN,TRA2B,NECAB1,CSMD1,UBE2H,VLDLR,TBC1D15,ZFP37,SMARCAD1,RTN4" MicroRNA hsa-miR-6854-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.40E-08 2.46E-04 6.79E-08 6.25E-07 16 83 "CDR1,SEC24C,PPP1R16B,KLHL3,CAMKK2,PCDH17,NKD1,SLC35G1,CYP27C1,GPSM2,PLEC,FITM2,PTGR2,NCBP3,RMI1,KLHL7" MicroRNA hsa-miR-4793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.41E-08 2.47E-04 6.79E-08 6.25E-07 21 141 "TAOK1,SMIM17,BAG4,IGSF6,PCDH17,IL6R,MAPT,CHIC1,PIK3R1,KCTD15,ZMAT4,ALG9,STX1B,SEMA6D,PEAR1,BDP1,FNBP1,ELOVL4,MGAT5B,ZNF70,ZNF195" MicroRNA hsa-miR-4290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.55E-08 2.54E-04 7.00E-08 6.45E-07 17 94 "TMEM132B,CS,RGS6,WDPCP,APC2,ANKMY1,CSDC2,CRCP,PRRC2B,MMP17,KCTD15,CYB561D1,MAPKBP1,NFASC,BCL2L13,MTCH1,KCNK12" MicroRNA hsa-miR-431:PITA hsa-miR-431:PITA_TOP PITA 4.55E-08 2.54E-04 7.00E-08 6.45E-07 17 94 "ABCD2,DPY19L3,KALRN,SOCS6,NRXN3,CLTC,HIPK3,FGF12,NRCAM,DIRAS2,SH3TC2,CPEB3,CPEB4,CAMTA1,LYPD6,LAMP5,RNF103" MicroRNA hsa-miR-4315:mirSVR_highEffct hsa-miR-4315:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.58E-08 2.57E-04 7.06E-08 6.50E-07 22 154 "SUGT1P4-STRA6LP-CCDC180,PTBP2,RUNX1T1,CCPG1,CLOCK,DDX46,EDN3,PRELID3A,MSTN,GPD2,SHISA6,TMEM240,SLC35G1,PRIMPOL,SH3GL3,RGL1,ADGRL3,AP4E1,TP53BP2,SSBP2,VPS35L,PLSCR4" MicroRNA hsa-miR-4639-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-08 2.58E-04 7.09E-08 6.53E-07 14 63 "FZD9,CALM1,UBE2E3,ZBED3,MAP4K5,ZNF678,KCNB1,PDPK1,PSAT1,FBXW7,SGK1,SLC6A8,NACC2,SLC38A1" MicroRNA hsa-miR-1297:Functional MTI Functional MTI miRTarbase 4.67E-08 2.61E-04 7.19E-08 6.62E-07 25 194 "MTA3,ZNF608,PDE4DIP,KIAA0408,ZBTB24,SACS,RGS17,FKTN,TNRC6A,ZBTB45,EID2B,MAT2A,BLOC1S2,ZNF426,PSAT1,NWD1,SLC25A36,ARMH4,FAM126B,DIP2A,ALG1,AGTPBP1,ASXL3,SSBP2,UBE2H" MicroRNA hsa-miR-3922-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.71E-08 2.64E-04 7.25E-08 6.68E-07 15 73 "ADCY5,INTS2,SUMF2,LETMD1,SCML2,SLC37A3,IBA57,KSR2,SDK2,PPP3CC,PSD,TAL1,NSD1,NR2E1,ZNF70" MicroRNA hsa-miR-6858-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.00E-08 2.79E-04 7.68E-08 7.07E-07 21 142 "XKR4,STOML1,NCOR2,UBXN2A,TOM1,APC2,ANKMY1,CELF1,TRAF3IP2,CYP46A1,LYVE1,CRCP,MKLN1,STRN3,MAGEL2,NCBP3,FAM192A,DIP2A,USP1,DHX33,MSRB3" MicroRNA hsa-miR-1224-3p:PITA hsa-miR-1224-3p:PITA_TOP PITA 5.10E-08 2.85E-04 7.84E-08 7.22E-07 18 106 "ADCY6,CDC42BPA,CABP7,PTBP2,NRXN3,HECTD1,CRY2,PPP1R16B,ALKBH8,ABCC5,SUCO,TTBK1,GRIN2D,MPP2,PDPK1,FNIP1,BTBD3,CAMTA1" MicroRNA hsa-miR-6811-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.10E-08 2.85E-04 7.84E-08 7.22E-07 18 106 "TMEM184B,ZNF385A,UBXN2A,PITPNC1,SNX29,ADAM28,RABL2A,HAS2,TNFAIP8L3,RBPJ,GPR155,MEIS1,ZDHHC14,NFASC,GPRIN3,ZNF708,ZNF17,HNRNPA3" MicroRNA hsa-miR-891a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.16E-08 2.89E-04 7.93E-08 7.30E-07 22 155 "CLK4,XKR4,ARHGDIA,LDHD,SYNJ2,CFAP410,ENTPD4,AMOTL2,SEC23B,PARD3B,IBA57,ZNF678,GPR155,MYCN,GPSM2,APTX,PEX26,ANKRD36,KLHL7,ALG1,ZNF34,THRA" MicroRNA hsa-miR-3671:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.16E-08 2.89E-04 7.93E-08 7.30E-07 22 155 "TXNDC16,CACNA1A,ANKRD46,YAF2,COQ7,IQCG,MPP6,SRCAP,TCERG1,TNRC6A,PDE3A,FAM98B,PPARA,SH3TC2,TMLHE,FAM126B,PEG10,PRRC2C,FAM208A,ZNF225,SLC38A1,PRDM10" MicroRNA hsa-miR-3915:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.26E-08 2.95E-04 8.09E-08 7.45E-07 20 130 "ELFN2,APBB2,CACNA1B,GAPVD1,RAB39B,SYNCRIP,MIER3,ZFYVE27,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,NMNAT2,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-100:mirSVR_highEffct hsa-miR-100:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.32E-08 2.98E-04 8.17E-08 7.53E-07 19 118 "NCOR2,MYEF2,HS3ST2,SLC29A4,FGFR3,TUBGCP4,RNF165,MIER3,MBNL1,CLDN11,PPP3CA,RAD51D,ERI2,AP1AR,PRRC2C,SLC44A1,ZNF19,DHX33,WNK3" MicroRNA hsa-miR-548m:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.35E-08 2.99E-04 8.21E-08 7.56E-07 17 95 "PCDH19,TNRC6C,CA12,LONRF2,CLCN3,PCDH17,RNPS1,PRUNE2,FUT10,BLOC1S2,PCDH9,CNTLN,CSRNP3,MPRIP,RPRM,SLC38A1,HNRNPA3" MicroRNA hsa-miR-4494:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.35E-08 2.99E-04 8.21E-08 7.56E-07 17 95 "ARNTL,DOCK11,C2CD2,KIAA0586,ZC3H11A,VPS13B,PTPRT,RNFT2,SHISA6,KCTD6,ATP8B4,FNDC3A,AGTPBP1,PUM2,VSNL1,TFIP11,MPPE1" MicroRNA hsa-miR-6073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.35E-08 2.99E-04 8.21E-08 7.56E-07 17 95 "PHF12,ARNTL,FOXN3,HECTD1,IP6K1,MTX3,DCTN4,MALT1,IL6ST,ZNF678,KIF5A,TTYH2,AFF1,RDX,KIF27,PEX26,ZNF24" MicroRNA hsa-miR-20b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.35E-08 2.99E-04 8.21E-08 7.56E-07 17 95 "PTCHD1,SLC24A4,TXNDC16,PHF12,APAF1,RASL11B,SLC16A4,HECTD1,AKAP12,SOCS5,DNAJB6,MTHFD2,IL6ST,N6AMT1,NPTX2,KSR2,CBX5" MicroRNA hsa-miR-6756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.52E-08 3.09E-04 8.46E-08 7.79E-07 24 182 "ASGR1,CBS,NUMBL,PLCXD3,CYBB,IP6K1,KIAA0319,KLHL5,PHF20L1,STARD3NL,REEP2,UFM1,CELF1,GALC,KCNMB4,METTL21A,STMN1,LSAMP,MYO5A,POU6F1,GTDC1,TMLHE,KIRREL1,LAT2" MicroRNA hsa-miR-3121-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.66E-08 3.16E-04 8.67E-08 7.98E-07 21 143 "WDR35,DPY19L3,CPS1,PDE4DIP,DGKB,FEM1B,SYNCRIP,ST6GALNAC3,FUT9,GPR75,TNRC6A,RASSF8,AGFG1,ZIC5,KITLG,TMEM231,ALG9,NCBP3,TAL1,TUBB2A,RPL7L1" MicroRNA "AAGTCCA,MIR-422A:MSigDB" "AAGTCCA,MIR-422A:MSigDB" MSigDB 5.70E-08 3.19E-04 8.73E-08 8.04E-07 14 64 "EDN1,PTPRT,FRMD5,STXBP5,HECTD2,NTRK3,PPP3CA,DHX30,UHRF1BP1L,IQSEC2,NEK4,SYN2,CUX2,NSD1" MicroRNA "AAGTCCA,MIR-422B:MSigDB" "AAGTCCA,MIR-422B:MSigDB" MSigDB 5.70E-08 3.19E-04 8.73E-08 8.04E-07 14 64 "EDN1,PTPRT,FRMD5,STXBP5,HECTD2,NTRK3,PPP3CA,DHX30,UHRF1BP1L,IQSEC2,NEK4,SYN2,CUX2,NSD1" MicroRNA hsa-miR-6511b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.92E-08 3.31E-04 9.07E-08 8.35E-07 18 107 "TMEM184B,ZNF385A,UBXN2A,PITPNC1,SNX29,ADAM28,RABL2A,HAS2,TNFAIP8L3,RBPJ,GPR155,MEIS1,ZDHHC14,NFASC,GPRIN3,ZNF708,ZNF17,HNRNPA3" MicroRNA hsa-miR-671-5p:PITA hsa-miR-671-5p:PITA_TOP PITA 6.00E-08 3.36E-04 9.19E-08 8.46E-07 20 131 "PPFIA3,HCN2,CFL2,IST1,PHC2,CELSR3,DLC1,GGT7,MARK1,ADAM11,SAMD5,PTPRD,ROBO2,BTBD3,SPTB,CAMTA1,WSCD1,SATB2,VSNL1,FZD3" MicroRNA "ACCAATC,MIR-509:MSigDB" "ACCAATC,MIR-509:MSigDB" MSigDB 6.21E-08 3.47E-04 9.51E-08 8.75E-07 12 46 "GAD1,MEIS1,ENPP2,USP47,PRRC2C,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" MicroRNA hsa-miR-6891-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-08 3.50E-04 9.58E-08 8.82E-07 16 85 "C3orf14,CFAP410,CLTC,IGDCC3,ERBB2,MRPL37,GCK,PCDH17,KCNN1,NCR3LG1,PEX2,STX1B,VLDLR,DHX33,URM1,GAN" MicroRNA hsa-miR-6795-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-08 3.52E-04 9.62E-08 8.85E-07 17 96 "ASPA,HCN2,CYBB,SEPT9,FAM107A,PADI2,SHISA6,RDX,GTDC1,SETD5,ZFP1,ZHX3,NSFL1C,THRA,ZNF24,URM1,PPP1R3F" MicroRNA "GGCACAT,MIR-455:MSigDB" "GGCACAT,MIR-455:MSigDB" MSigDB 6.33E-08 3.54E-04 9.69E-08 8.92E-07 13 55 "RTL9,SEMA4G,CDK13,CACNB4,RIMS4,SLITRK5,PLCXD3,USP3,EDN1,GABRB3,STX1B,SOX11,DOCK9" MicroRNA hsa-miR-8082:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-08 3.54E-04 9.69E-08 8.92E-07 25 197 "SEMA7A,DOCK11,CAMK2A,SPATA2,TUBA1B,TRAF3IP2,TNRC6A,GLUL,RAB40B,GPR155,OLA1,ZNF426,CEP97,SLC25A36,ELP2,HSD11B1L,SCN2B,HSPA4L,NUBPL,FAM126B,NFASC,KIAA0930,RPL7L1,ZNF708,KAT6A" MicroRNA hsa-miR-6769b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.36E-08 3.56E-04 9.73E-08 8.96E-07 26 211 "XKR4,ADCY6,SORCS2,ARHGDIA,LDLRAD4,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,TMCC2,ZNF391,ANKMY1,AMOTL2,SHISA6,KCNN3,POU6F1,KANSL1,C12orf49,GALNT10,ERC1,CRTC1,DPYSL5,FRMD6" MicroRNA hsa-miR-1227-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.36E-08 3.56E-04 9.73E-08 8.96E-07 26 211 "XKR4,CBS,NRXN3,HINFP,RASSF2,DNAL1,SPATA2,MTX3,ATP13A4,SLC2A6,DDX19B,IBA57,CHST6,ZC3H12B,RBBP8,TRIM68,BTBD3,SEPHS1,ATF7IP,SSTR2,USP22,PPIL6,SSBP2,RPL7L1,UGT8,SLC30A4" MicroRNA hsa-miR-6501-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.52E-08 3.65E-04 9.96E-08 9.17E-07 22 157 "AXIN2,BARD1,DDR1,USP2,ARHGAP32,TMEM170A,E2F5,CRCP,GPR75,TNRC6A,IPO5,MN1,SLC11A2,KLHDC8A,CCDC25,PEX26,PDZD2,TROVE2,AGTPBP1,TMEM9,SSBP2,TBC1D15" MicroRNA hsa-miR-2114-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.90E-08 3.86E-04 1.06E-07 9.71E-07 15 75 "HECW2,LONRF2,SPATA2,C2CD2L,TMCC2,MTSS1L,CELF1,TDRKH,KAT7,HAS2,NEGR1,NCR3LG1,ATXN2,PKNOX2,PEG10" MicroRNA hsa-miR-4723-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-08 3.92E-04 1.07E-07 9.85E-07 26 212 "XKR4,ADCY6,SORCS2,ARHGDIA,LDLRAD4,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,TMCC2,ZNF391,ANKMY1,AMOTL2,SHISA6,KCNN3,POU6F1,KANSL1,C12orf49,GALNT10,ERC1,CRTC1,DPYSL5,FRMD6" MicroRNA hsa-miR-3183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-08 3.92E-04 1.07E-07 9.85E-07 26 212 "XKR4,ADCY6,SORCS2,ARHGDIA,LDLRAD4,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,TMCC2,ZNF391,ANKMY1,AMOTL2,SHISA6,KCNN3,POU6F1,KANSL1,C12orf49,GALNT10,ERC1,CRTC1,DPYSL5,FRMD6" MicroRNA hsa-miR-6861-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.93E-04 1.07E-07 9.86E-07 14 65 "CC2D2A,AQP6,UBXN2A,FEM1B,EGR3,C8orf37,LYVE1,MPP2,KCNIP3,AMBRA1,MYH15,MBD5,ZNF610,DHX33" MicroRNA hsa-miR-3908:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.93E-04 1.07E-07 9.86E-07 14 65 "TAOK1,CASK,CPEB2,FAM13A,SESN1,IL6ST,METTL21A,FIGN,KCNIP3,HSPA4L,CBX5,RGMB,DHX33,GAN" MicroRNA hsa-miR-663b:PITA hsa-miR-663b:PITA_TOP PITA 7.02E-08 3.93E-04 1.07E-07 9.86E-07 14 65 "ASIC1,ADGRB1,SH2B1,NRN1,ACSL4,LRRC75A,MN1,GIT1,PDPK1,USP47,GTDC1,FAM214B,PUM2,TMEM198" MicroRNA hsa-miR-325:PITA hsa-miR-325:PITA_TOP PITA 7.02E-08 3.93E-04 1.07E-07 9.86E-07 14 65 "CDH2,EDN1,CELF1,STAU2,TPPP,GPR85,CCSER2,RORB,TMCC1,CDK19,SYT1,ANKRD28,RIMBP2,WNK3" MicroRNA hsa-miR-935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.93E-04 1.07E-07 9.86E-07 19 120 "RNF150,ATP1B3,TBPL1,PITPNC1,MTX3,ABCC5,ASB3,FLT1,NBEA,PKM,FITM2,NWD1,PCMTD2,TMEM200C,SLC12A2,ITPRID2,SUPT5H,LMF1,ZFP37" MicroRNA hsa-miR-2276-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.32E-08 4.09E-04 1.12E-07 1.03E-06 22 158 "XKR4,SPOP,CDC14B,ARSE,RNF14,MATR3,HEYL,MRO,TUBD1,SLC43A2,MED12L,MSANTD4,CRCP,LIMS1,MAPT,STRN3,APTX,ZSCAN2,DIP2A,TPCN2,ARL10,ERCC6L2" MicroRNA hsa-miR-409-5p:TargetScan hsa-miR-409-5p TargetScan 7.36E-08 4.12E-04 1.12E-07 1.03E-06 17 97 "ADCY6,GALNT13,DPY19L3,AIF1L,CELSR3,EIF1,RASL12,MMADHC,PPARGC1A,PCLO,KCNB1,PPM1L,PEG10,ARHGAP26,CAMTA1,KLC2,NETO2" MicroRNA hsa-miR-3976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.43E-08 4.16E-04 1.13E-07 1.04E-06 16 86 "ARSE,BCL7A,PDE4DIP,TMEM170A,DBT,DLC1,EFCAB2,SPECC1,ATOH8,NKAIN1,SLC6A8,SEPHS1,ANKRD36,SEPT8,NR2E1,SPIRE1" MicroRNA hsa-miR-7851-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.73E-08 4.33E-04 1.18E-07 1.08E-06 25 199 "XKR4,TRMT9B,CDC14B,ASPA,CDR1,NRG2,RASA4,IRAK4,MRNIP,TRMO,DISC1,LILRA2,KAT7,DDX19B,IBA57,LIMS1,QDPR,PGBD4,NFASC,PRRC2C,FAM208A,CLASP1,BHLHB9,SSBP2,ZNF154" MicroRNA hsa-miR-3195:mirSVR_lowEffct hsa-miR-3195:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.77E-08 4.35E-04 1.18E-07 1.09E-06 20 133 "PPFIA3,ASGR1,KSR1,SULT4A1,STARD3,DCLK2,GP1BB,CLASRP,CELF5,GIT1,ZNF862,CDK18,PFKFB4,NECAB2,RFX2,SLC11A1,ADHFE1,HIF3A,CASC15,JPH3" MicroRNA hsa-miR-3200-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.97E-08 4.46E-04 1.21E-07 1.12E-06 13 56 "KLHL32,PPP1R16B,LONRF1,SPATA2,TNRC6A,CHIC1,NUCB2,GRAMD1C,SLC25A36,KANSL3,ZNF45,TFIP11,ZXDA" MicroRNA "CAGGTCC,MIR-492:MSigDB" "CAGGTCC,MIR-492:MSigDB" MSigDB 7.97E-08 4.46E-04 1.21E-07 1.12E-06 13 56 "NCOA1,DBN1,RNF165,MAT2A,NPTX1,PFKFB2,SCN2B,TRA2B,CPEB3,AMBRA1,CYB561A3,SLC44A1,SMARCAD1" MicroRNA hsa-miR-5697:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-08 4.47E-04 1.21E-07 1.12E-06 23 172 "ZNF608,CDC14B,CCNT1,KIAA0408,SACS,PLEKHA1,RGS17,SLC43A2,TXNL4A,TNRC6A,ZBTB45,LIFR,MAT2A,BLOC1S2,ZNF426,SLC25A36,PGBD4,ARMH4,FAM126B,TROVE2,DIP2A,ALG1,UBE2H" MicroRNA hsa-miR-642b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.06E-08 4.51E-04 1.23E-07 1.13E-06 12 47 "XKR4,SORCS2,CACNA1A,ZNF385A,NEURL4,SLC35G1,NPTX1,PSAT1,DPF2,WDR37,ALG1,ZDHHC20" MicroRNA hsa-miR-6514-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.15E-08 4.56E-04 1.24E-07 1.14E-06 21 146 "SEMA7A,BACH1,RUNX1T1,CCNT1,HECTD1,DNAL1,TRAF3IP2,GLUL,RAB40B,HSF2,GPR155,ZNF426,ELP2,SCN2B,HSPA4L,NUBPL,FAM126B,PEG10,ZC3H4,KIAA0930,ZNF708" MicroRNA hsa-miR-7157-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.20E-08 4.59E-04 1.25E-07 1.15E-06 22 159 "FMNL2,SLC24A4,ZNF582,MTMR3,ISPD,PLXNA4,MAML1,YTHDC1,DMPK,FEM1B,PLEKHA1,SCML2,CELF1,ZNF680,GTDC1,SALL1,ZKSCAN3,PEG10,MGAT5B,WRN,DHX33,SPATA13" MicroRNA hsa-miR-6794-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.20E-08 4.59E-04 1.25E-07 1.15E-06 22 159 "TEX22,PHF12,CDK13,C2CD2,RGS6,SUSD5,DBT,TMCC2,COQ7,SLC37A3,KAT7,ZDHHC15,NKD1,GPR137C,PPP2R5E,ELP2,CHD9,ANKRD36,UNC5B,ZC3H13,KLHL4,ZNF708" MicroRNA hsa-miR-4310:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.20E-08 4.59E-04 1.25E-07 1.15E-06 22 159 "FMNL2,SLC24A4,ZNF582,MTMR3,ISPD,PLXNA4,MAML1,YTHDC1,DMPK,FEM1B,PLEKHA1,SCML2,CELF1,ZNF680,GTDC1,SALL1,ZKSCAN3,PEG10,MGAT5B,WRN,DHX33,SPATA13" MicroRNA hsa-miR-630:Functional MTI Functional MTI miRTarbase 8.31E-08 4.65E-04 1.26E-07 1.16E-06 15 76 "CPS1,JAKMIP2,MRO,EIF5,PLEKHA1,STARD3NL,DCTN4,LILRA2,PTPRT,IL6R,LSAMP,DIP2A,TLR4,VLDLR,ZNF70" MicroRNA hsa-miR-3977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.31E-08 4.65E-04 1.26E-07 1.16E-06 15 76 "ZNF578,ARSE,PRC1,MTMR7,CNRIP1,WDPCP,LILRA2,ZBTB49,KPNA5,LSAMP,RFX3,ERBIN,ZNF610,UBE2H,URM1" MicroRNA hsa-miR-4726-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.53E-08 4.78E-04 1.30E-07 1.19E-06 25 200 "PTCHD1,MTA3,DYNLL1,TMEM184B,RTTN,RNF14,IP6K1,CNNM1,HEYL,APH1A,MSANTD4,KIAA1958,BACH2,NKD1,IL6R,THYN1,FAM216A,PTPRB,ZNF844,RGS12,SHMT2,CYB561A3,ERCC6L2,TSPAN11,SLC38A1" MicroRNA hsa-miR-938:PITA hsa-miR-938:PITA_TOP PITA 8.61E-08 4.82E-04 1.31E-07 1.20E-06 17 98 "KLHL13,APAF1,USP6,DGKI,NUMBL,RCHY1,SACS,AFF2,FRMD3,KIF2A,RIPOR1,SOX11,TRIM2,TIAM1,FAM155A,PRDM8,PHTF2" MicroRNA hsa-miR-4258:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.80E-08 4.92E-04 1.34E-07 1.23E-06 16 87 "MARCH4,ZMYM4,NUMBL,CBARP,ZNF385A,TUBD1,SLC43A2,FDFT1,GFER,KIAA1958,KIFC3,MAT2A,RXRA,SEPT8,STAC2,SSBP2" MicroRNA hsa-miR-548as-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.89E-08 4.97E-04 1.35E-07 1.24E-06 23 173 "XKR4,SLC24A4,TNRC6C,ZNF385A,CTH,E2F6,AFF2,MTHFD2,PRRC2B,CACFD1,MIER3,NEGR1,ITPKB,JAK2,MAT2A,SAMD5,ROBO1,PCMTD2,ATF7IP,SOX3,CLASP1,CADM2,WNK3" MicroRNA hsa-miR-100-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.18E-08 5.14E-04 1.39E-07 1.28E-06 18 110 "ASPA,STX16,SRSF11,CNN3,CNRIP1,NECTIN3,PLCXD3,KATNAL1,FOXO3,THYN1,PURG,FAM161B,SGK1,SOX3,ZHX3,SYPL1,BCL2L13,VLDLR" MicroRNA hsa-miR-208a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.18E-08 5.14E-04 1.39E-07 1.28E-06 18 110 "PCDH19,CDH2,LRIG1,SOCS5,SYNCRIP,UFM1,SRRM4,SLC2A6,RBPJ,SLC35G1,MTRF1L,CEP97,ATP8B4,KIF21A,SNAP25,LRRC8A,JMJD1C,ZDHHC20" MicroRNA hsa-miR-3156-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.21E-08 5.15E-04 1.40E-07 1.29E-06 19 122 "RNF150,MTA3,OSBPL1A,PHF12,BACH1,CAMK2G,IP6K1,CELSR3,MRPL37,POLL,MN1,CNNM2,SH3TC2,SPIN3,STUM,KIF21A,KANSL3,DPYSL5,GAN" MicroRNA hsa-miR-3121-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.21E-08 5.15E-04 1.40E-07 1.29E-06 19 122 "KCTD16,SCARB1,BAG4,TOGARAM2,UBXN2A,RASSF2,ZNF585B,MAP4K5,SAMD5,GPR137C,PAX6,PDPK1,ZMAT4,SETD5,BTBD3,SLC6A8,UHRF1BP1L,ARHGAP26,NR2E1" MicroRNA hsa-miR-323-5p:PITA hsa-miR-323-5p:PITA_TOP PITA 9.98E-08 5.58E-04 1.51E-07 1.39E-06 15 77 "ELFN2,SPOP,ATP1B3,CNR1,CLIP3,PSD2,MIER3,MYLK2,NNAT,PSD,DPF2,CLASP2,MTMR14,WIPF1,NAV3" MicroRNA hsa-miR-4696:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-07 5.60E-04 1.52E-07 1.40E-06 20 135 "ARSE,CALM1,PUM1,TMEM170A,SEC23B,TRMO,CRCP,GPR75,KCNB1,CHST6,NPTX1,SLC11A2,NDUFS7,KLHDC8A,PEX26,MPRIP,SATB2,CRTC1,SSBP2,TBC1D15" MicroRNA hsa-miR-3679-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-07 5.79E-04 1.57E-07 1.44E-06 21 148 "AK2,TAOK1,LGR5,ZNF385A,HINFP,TBC1D5,KLHL5,FAM13A,IP6K2,SEMA4D,ST6GALNAC3,SRRM4,MITF,TMOD2,PKIA,PTPRE,NSFL1C,ALG1,TNS1,DOK6,SLC38A1" MicroRNA hsa-miR-6855-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.81E-04 1.57E-07 1.45E-06 16 88 "ELFN2,KIAA0040,DBN1,MTX3,E2F6,MRNIP,FGF1,PDE4D,KCTD15,FAM126B,ZNF621,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-4513:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.81E-04 1.57E-07 1.45E-06 16 88 "ELFN2,KIAA0040,DBN1,MTX3,E2F6,MRNIP,FGF1,PDE4D,KCTD15,FAM126B,ZNF621,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-573:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-07 5.89E-04 1.59E-07 1.47E-06 19 123 "DYNLL1,CLCN3,C3orf18,FKTN,FGFR1,FICD,MARK1,MYO5A,GPR137C,SLC25A23,FNDC3A,ANKRD6,CPEB4,ARHGAP26,DDN,TBCEL,ZNF106,KAT6B,ZKSCAN5" MicroRNA hsa-miR-1184:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-07 5.92E-04 1.60E-07 1.47E-06 18 111 "PHF12,NUMB,STX16,TMEM184B,TMEM170A,ZBTB24,TMEM132C,GLUL,ATOH8,IDH3A,IL6R,IBA57,ENPP2,BDP1,DICER1,WBP2,UBE2H,SLC30A3" MicroRNA hsa-miR-720:mirSVR_highEffct hsa-miR-720:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-07 5.92E-04 1.60E-07 1.47E-06 18 111 "ADCY6,HECTD1,ABI3BP,CS,GOLGA7,KHDRBS3,ADAMTS13,RBPJ,DNHD1,BCAS3,RASGRF1,RNASE1,KLHDC8A,SNX22,TSPYL2,SST,ARL10,NHSL1" MicroRNA hsa-miR-5571-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-07 6.27E-04 1.70E-07 1.56E-06 26 217 "AS3MT,ZNF578,PARG,ATP1B3,ALDH7A1,CAMK2G,CLOCK,HINFP,MRNIP,CRCP,KPNA5,L1CAM,NCOA7,AFF1,FAM216A,ZNF844,PGBD4,SGK1,PEX26,TET1,ZFP1,ZNF415,ASTN2,PCDHA6,REEP1,ZNF195" MicroRNA hsa-miR-141-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-07 6.34E-04 1.71E-07 1.58E-06 20 136 "MTA3,SORCS2,WDR35,SMIM17,BID,SPAG9,TOGARAM2,TM9SF4,TMEM132C,ZNF638,ATXN2L,MYO5A,EPB41L4B,MSANTD2,AP1AR,ATXN2,KANSL3,DOK6,FRMD6,GAN" MicroRNA hsa-miR-885-3p:mirSVR_highEffct hsa-miR-885-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-07 6.51E-04 1.76E-07 1.62E-06 21 149 "KIAA1324,SUGT1P4-STRA6LP-CCDC180,INSYN2B,AHCTF1,RGS6,EBI3,EGFR,GOLGA7,VPS26C,MYLK2,ZNF827,GPR173,BCAS3,WBP1L,CCDC40,STK32B,MYO16,ZSWIM8,AGTPBP1,TPM1,MEIS3" MicroRNA hsa-miR-5683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.54E-04 1.77E-07 1.63E-06 17 100 "ZNF608,RUNX1T1,HINFP,DLC1,SCARA3,MTHFD2,ELOVL5,KCNN3,PDPK1,KANSL1,RDX,KIF21A,ADAMTS17,SYT1,TCEA1,CBX5,USP1" MicroRNA hsa-miR-4303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.54E-04 1.77E-07 1.63E-06 17 100 "CST3,GREB1,SLC43A2,MRVI1,CELF1,BLOC1S2,NFIX,NPTX2,GPR173,PGBD4,SEMA6D,CSRNP3,FAM126B,NSD1,TUBB2A,ZNF74,ZXDA" MicroRNA hsa-miR-4717-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-07 6.68E-04 1.80E-07 1.66E-06 15 78 "ZNF578,HAPLN1,HIPK3,ZBED3,SPECC1,TPK1,SEPT9,ADAM28,QDPR,PNMA8A,STUM,ALG1,NACC2,WRN,ZDHHC20" MicroRNA hsa-miR-3201:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.81E-04 1.84E-07 1.69E-06 11 40 "CA8,CDC25B,CLCN3,CELF1,KCNMB4,BACH2,PTPRD,CEP97,MBD5,PCDHA6,PARD3" MicroRNA hsa-miR-4329:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.82E-04 1.84E-07 1.69E-06 18 112 "KLHL32,CC2D2A,TRMT9B,LONRF2,SLC43A2,MRVI1,SIGLEC8,GPR173,PRKAB2,CEP97,CSRNP3,SLC37A2,TBC1D15,ZNF45,ZNF74,ZNF177,TMEM198,PHTF2" MicroRNA hsa-miR-5007-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.82E-04 1.84E-07 1.69E-06 18 112 "ABCF1,VXN,TBRG4,TMEM184B,RTTN,SEC14L5,DBT,DNAH9,RGS17,COQ7,SPECC1,SRCAP,SCIN,IBA57,MBD1,PIK3R1,MTMR10,SATB2" MicroRNA hsa-miR-6814-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.84E-04 1.84E-07 1.70E-06 23 176 "AS3MT,RNF157,CDC14B,CACNA2D1,CSNK1E,UBXN2A,SLC43A2,ANKFY1,TRAF3IP2,RBPJ,SLC35G1,KCNH2,KCNK3,MBD1,PDE3A,EPB41L4B,PGBD4,SPIN3,ASAP3,TMCC1,MPRIP,KLHL7,LAT2" MicroRNA hsa-miR-4711-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.85E-04 1.85E-07 1.70E-06 16 89 "PTCHD1,IGLON5,CHRDL1,FEM1B,KATNAL1,EFCAB2,CELF1,MMADHC,AP4S1,IGF1,KCNN3,MBNL1,MITF,NLGN3,ARHGEF9,ZDHHC20" MicroRNA hsa-miR-3133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-07 7.04E-04 1.90E-07 1.75E-06 24 190 "TMCC3,CC2D2A,TAOK1,TRMT9B,ATP2A2,LDHD,FAM169A,MFAP3L,RCAN1,FRY,HAS2,ZIC5,RBPJ,LAMA2,MAT2A,NEXMIF,KCTD15,ZNF426,FIGN,MYO16,BDP1,SEPT8,SLC44A1,RNF146" MicroRNA hsa-miR-4646-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-07 7.16E-04 1.93E-07 1.78E-06 14 68 "MTUS1,CA12,PITPNM3,UBXN2A,CELSR3,CELF1,METTL21A,SHC3,SEPT4,RDX,CSRNP3,GALNT10,NR2E1,VLDLR" MicroRNA hsa-miR-5197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-07 7.18E-04 1.93E-07 1.78E-06 22 163 "AK2,SEMA7A,ARMC12,SFMBT2,HAP1,C4orf33,ARHGEF6,VCAN,FAM107B,TNRC6A,RNF165,RABL2A,COMMD5,GPR173,FIGN,SLC25A36,BTBD3,ERBIN,SATB2,RPRM,WRN,FRMD6" MicroRNA hsa-miR-517b:PITA hsa-miR-517b:PITA_TOP PITA 1.33E-07 7.45E-04 2.00E-07 1.85E-06 12 49 "CAMK2G,ERC2,MATR3,KATNAL1,MEIS2,MITF,SMPD3,SHC4,TSC1,TMEM198,PRDM8,MPPE1" MicroRNA hsa-miR-550a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-07 7.45E-04 2.00E-07 1.85E-06 12 49 "FEM1B,TUBD1,SYNCRIP,C2orf72,EFHB,SLC11A2,POLR2F,PKIA,MAPK3,ZNF621,HPS4,URM1" MicroRNA hsa-miR-208b-3p:Functional MTI Functional MTI miRTarbase 1.33E-07 7.45E-04 2.00E-07 1.85E-06 12 49 "AXIN2,QKI,LIN54,DGKG,CPEB2,CELF1,IQGAP2,MAPK10,ZNF844,ASAP3,AMBRA1,TUBB2A" MicroRNA hsa-miR-3617-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-07 7.60E-04 2.04E-07 1.88E-06 17 101 "KLHL32,AXIN2,THSD7A,LIN54,GOLT1B,DLC1,IQGAP2,P2RY1,MAPK10,FIGN,NBPF1,ANKRD36,LIMCH1,POGZ,SLC35G2,ZNF106,CLDND1" MicroRNA hsa-miR-668-3p:TargetScan hsa-miR-668-3p TargetScan 1.37E-07 7.65E-04 2.06E-07 1.90E-06 19 125 "KCTD16,CDK13,MTMR3,CAMK2G,CDH2,FHL5,RCHY1,PHF20L1,EMX2,NEGR1,IL6ST,ITPKB,MAPT,KITLG,NFYA,CNOT4,PAX6,PTPRG,SCN2B" MicroRNA hsa-miR-4534:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-07 7.74E-04 2.08E-07 1.92E-06 25 205 "SEMA7A,DOCK11,CAMK2A,SPATA2,TUBA1B,TRAF3IP2,TNRC6A,GLUL,RAB40B,GPR155,OLA1,PKM,ZNF426,CEP97,SLC25A36,ELP2,HSD11B1L,SCN2B,HSPA4L,NUBPL,FAM126B,KIAA0930,RPL7L1,ZNF708,KAT6A" MicroRNA hsa-miR-1251-5p:TargetScan hsa-miR-1251-5p TargetScan 1.42E-07 7.97E-04 2.14E-07 1.97E-06 15 79 "BRAP,APBB2,ERBB4,MTHFD2,RNF165,HLF,IGF1,KIF5A,MMP16,NOVA2,PKIA,GTDC1,FIGN,CBX5,NETO1" MicroRNA hsa-miR-4528:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-07 7.97E-04 2.14E-07 1.97E-06 15 79 "MTA3,WDR35,PUM1,MFAP3L,MSANTD4,TNRC6A,BVES,NEGR1,ZNF426,KANSL1,PBRM1,FNBP1,SOX11,TACC1,CLDND1" MicroRNA hsa-miR-4802-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-07 8.05E-04 2.16E-07 1.99E-06 16 90 "DOCK11,BACH1,RUNX1T1,CCNT1,HECTD1,NCOR2,DNAL1,SPATA2,ZBTB45,HSF2,SMIM7,CNNM2,CEP97,PEG10,ZSCAN29,ZC3H4" MicroRNA hsa-miR-652:mirSVR_highEffct hsa-miR-652:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-07 8.05E-04 2.16E-07 1.99E-06 16 90 "KLHL32,ALCAM,AKAP6,PDE4DIP,DTNA,KRBA2,PHC2,SRRM1,TNRC6A,GNAO1,ITGA7,KCNB1,FOXRED1,SS18,MPPE1,DNAH10" MicroRNA hsa-miR-494-3p:Functional MTI Functional MTI miRTarbase 1.45E-07 8.10E-04 2.18E-07 2.00E-06 20 138 "ELFN2,ARNTL,CNR1,SYNCRIP,PRRC2B,CREG2,TM6SF1,MINDY2,CEP97,ZNF532,TMLHE,SLC8A1,FNBP1,ITPRID2,SS18,ZEB1,ZNF24,EVI5,HNRNPA3,SPATA13" MicroRNA hsa-miR-6715b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-07 8.10E-04 2.18E-07 2.00E-06 20 138 "APAF1,NUMBL,DNAH9,TUBD1,IGSF6,TMEM132C,FDFT1,POLR1B,TXNL4A,ZIC5,RMI1,SBF1,SH3BP2,R3HDM2,UNC5B,GALNT17,TRPS1,TSN,RPL7L1,SIGLEC10" MicroRNA hsa-miR-532-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-07 8.25E-04 2.22E-07 2.04E-06 26 220 "PWWP2A,PTCHD1,PHF12,ARSE,ZNF582,CACNA1A,CAMK2G,CRY2,RIPOR2,CELSR3,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,POLL,HAS2,NFYA,PNMA3,ZNF844,SH3TC2,GSTCD,SMUG1,RUNDC3B,TSPAN11,DPYSL5,GAN" MicroRNA hsa-miR-6778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-07 8.58E-04 2.30E-07 2.12E-06 24 192 "PHF12,LONRF2,SUMF2,CRY2,FAM131B,DCAF8,IP6K1,E2F6,PHC2,TMTC1,AHDC1,NEGR1,KCNK3,PFKFB3,PMP22,PPARA,KLHDC8A,MRAS,SLC11A1,CAMTA2,RPRM,KLC2,CIAPIN1,WNK2" MicroRNA hsa-miR-1179:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-07 8.63E-04 2.31E-07 2.13E-06 13 59 "HACE1,TOGARAM2,LIN54,MAML1,DMPK,PLEKHA1,FOXO3,NEGR1,BLOC1S2,NFIX,PCSK1,SDK2,DIP2A" MicroRNA hsa-miR-3064-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-07 8.69E-04 2.33E-07 2.14E-06 14 69 "ELFN2,PHF12,MARCH3,CD99L2,AASDH,TMTC1,POLR1B,TPK1,CELF1,RBPJ,PLCL1,SH3TC2,ZNF138,SPATA13" MicroRNA hsa-miR-3128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-07 8.69E-04 2.33E-07 2.14E-06 14 69 "MTMR3,CCNT1,GOLGA7,ZNF234,PRRC2B,PADI2,PDE3A,DPF2,SEC31A,KANSL3,SLC6A8,KIAA0930,DPYSL5,FAM182B" MicroRNA hsa-miR-5695:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-07 8.71E-04 2.33E-07 2.15E-06 19 126 "ATP1B3,CACNA1A,SEC16A,TMTC1,CELSR3,BACH2,KNDC1,IL6R,KCNB1,MYO5A,NPTX1,CDK18,CYB561D1,PCMTD2,ATXN7,NFASC,NSD1,SLC44A1,SGK3" MicroRNA hsa-miR-192-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-07 8.71E-04 2.33E-07 2.15E-06 19 126 "NRXN3,CSNK1G3,IST1,EMX2,CELF1,ZNF546,KCNQ3,LSAMP,NTRK3,PDE3A,KANSL1,SNRK,RNASEL,SCP2,MRAS,SNAP25,FBXW11,ARL10,FXR1" MicroRNA hsa-miR-6857-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-07 8.81E-04 2.36E-07 2.17E-06 17 102 "PPFIA4,ARRB2,TPP1,KLHL3,APH1A,SRCAP,TNRC6A,SCIN,KCNN3,MSI1,NBL1,SLC25A23,COPZ1,UNC5B,CBX5,LAT2,CIAPIN1" MicroRNA hsa-miR-769-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-07 8.92E-04 2.39E-07 2.20E-06 22 165 "EMILIN3,CLOCK,INTS1,POM121,PHF20L1,FUT10,STMN1,CHST6,MXI1,NME4,GPR137C,PLEC,MINDY2,GALNT10,FAM126B,PEG10,STAU1,NSD1,TIAM1,UBC,RPL7L1,ZFAND5" MicroRNA hsa-miR-513c-5p:Functional MTI Functional MTI miRTarbase 1.61E-07 8.99E-04 2.41E-07 2.21E-06 18 114 "PHF12,PROM1,ZBED1,FEM1B,PLEKHA1,RGS17,COQ7,MSANTD4,TNRC6A,CCSER2,MAGEL2,PEX26,SLC6A8,VWCE,TMPO,RIMBP2,TBC1D15,WRN" MicroRNA hsa-miR-514b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-07 8.99E-04 2.41E-07 2.21E-06 18 114 "PHF12,PROM1,ZBED1,FEM1B,PLEKHA1,RGS17,COQ7,MSANTD4,TNRC6A,CCSER2,MAGEL2,PEX26,SLC6A8,VWCE,TMPO,RIMBP2,TBC1D15,WRN" MicroRNA hsa-miR-4307:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-07 8.99E-04 2.41E-07 2.21E-06 18 114 "CACNA1A,MYADM,DBN1,JAKMIP2,FEM1B,JKAMP,FYB1,TNRC6A,KCNMB4,IBA57,NELL2,GDPD1,PEX26,PEG10,POGZ,RPL7L1,ZNF28,GAL3ST3" MicroRNA hsa-miR-4468:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-07 9.19E-04 2.46E-07 2.26E-06 21 152 "XKR4,AK2,DOCK11,ST3GAL5,LRWD1,PLAA,UBXN2A,DNAH9,E2F6,FCF1,ZNF585B,MSANTD4,CRCP,TNRC6A,PRRC2B,RBPJ,IBA57,ZNF106,WBP2,DHX33,GAN" MicroRNA hsa-miR-99a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-07 9.29E-04 2.48E-07 2.29E-06 10 33 "CLTC,PUM1,KIAA0319,GSTM5,MAP4,MMP16,ZNF621,AGTPBP1,CCDC14,WIPF1" MicroRNA hsa-miR-3136-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-07 9.44E-04 2.52E-07 2.32E-06 16 91 "ELFN2,KIAA0040,DBN1,MTX3,MRNIP,FGF1,PDE4D,KCTD15,FAM126B,ZNF621,MPRIP,SULF2,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-1233:PITA hsa-miR-1233:PITA_TOP PITA 1.69E-07 9.44E-04 2.52E-07 2.32E-06 16 91 "FMNL2,AXIN2,SEMA4G,ARHGEF1,DLGAP2,MYEF2,ABCC5,PHC2,FGF13,AGFG1,NEK1,PIK3R1,ROBO1,SMPD3,CASC3,FAM214B" MicroRNA hsa-miR-4439:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-07 9.44E-04 2.52E-07 2.32E-06 16 91 "ELFN2,KIAA0040,DBN1,MTX3,MRNIP,FGF1,PDE4D,KCTD15,FAM126B,ZNF621,MPRIP,SULF2,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA "TCTATGA,MIR-376A:MSigDB" "TCTATGA,MIR-376A:MSigDB" MSigDB 1.69E-07 9.48E-04 2.53E-07 2.33E-06 15 80 "ANK2,CAPN3,USP6,SEPT7,CSNK1G3,FAM131B,GRIN3A,KHDRBS3,FERMT2,GRIK5,FBXO11,MBD5,LARP4,CUX2,CELF4" MicroRNA "TCTATGA,MIR-376B:MSigDB" "TCTATGA,MIR-376B:MSigDB" MSigDB 1.69E-07 9.48E-04 2.53E-07 2.33E-06 15 80 "ANK2,CAPN3,USP6,SEPT7,CSNK1G3,FAM131B,GRIN3A,KHDRBS3,FERMT2,GRIK5,FBXO11,MBD5,LARP4,CUX2,CELF4" MicroRNA hsa-miR-593-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-07 9.94E-04 2.65E-07 2.44E-06 22 166 "SPAG9,USP6NL,TMEM170A,C2CD2L,ERBB2,UFM1,SCIN,SYTL4,LSAMP,PALM,PDE3A,STRN3,NCBP3,TRA2B,FAM214B,MCF2L2,DIP2A,FAM208A,KIAA0930,SZT2,ZNF708,PLSCR4" MicroRNA hsa-miR-548v:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-07 1.02E-03 2.72E-07 2.51E-06 17 103 "RNF150,PITPNC1,STAMBP,RNPS1,TNRC6A,FICD,TTC13,NWD1,SLC25A36,SETD5,STUM,ZFP1,TMCC1,TCF12,SLC19A3,CFAP298,CIAPIN1" MicroRNA hsa-miR-4733-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-07 1.02E-03 2.72E-07 2.51E-06 17 103 "DNAH17,ATP2A2,CDC25B,EVI5L,DBT,DLC1,PRUNE2,DDX19B,SEPT4,NDUFS7,SEC31A,TRIM67,ZNF106,ZNF781,ZNF154,TMEM237,ZNF195" MicroRNA hsa-miR-2113:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-07 1.03E-03 2.75E-07 2.53E-06 21 153 "CLOCK,ZC3H11A,DMD,AFF2,DOT1L,SRRM4,SRCAP,CBX1,HECTD2,MITF,KSR2,PKIA,CNNM2,REV3L,CLIP1,MPRIP,ASTN2,ALG1,ZEB1,VSNL1,SLC38A1" MicroRNA hsa-miR-4735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-07 1.03E-03 2.76E-07 2.54E-06 23 180 "TMEM132B,FZD9,PTBP2,LETMD1,NSL1,CRY2,DBT,FARSB,C8orf37,SRRM4,MALT1,ZNF276,MXI1,GPR137C,FAM216A,PLCL1,FAM161B,TET1,AGTPBP1,KIAA0930,CBX5,SSBP2,HNRNPA3" MicroRNA hsa-miR-30a-3p:Functional MTI Functional MTI miRTarbase 1.86E-07 1.04E-03 2.78E-07 2.56E-06 24 194 "CDK13,ENTPD4,MAML1,YTHDC1,FAM107B,EIF1,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,KCTD6,EPB41L4B,SH3TC2,CCDC25,SCP2,GALNT10,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2,TUBA1A" MicroRNA hsa-miR-4642:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-07 1.07E-03 2.84E-07 2.61E-06 13 60 "ARHGEF7,CFAP410,CACNA2D1,CCNT1,PARD3B,KAT7,EID2B,MYCN,OLA1,CNNM2,DPF2,STX1B,TMPO" MicroRNA hsa-miR-3164:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-07 1.07E-03 2.84E-07 2.61E-06 13 60 "FMNL2,ELFN2,USP37,CA12,APPL1,TRMO,TJAP1,IL6ST,POLR2F,PEX26,ZFP1,LIMCH1,ZXDA" MicroRNA hsa-miR-346:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-07 1.10E-03 2.94E-07 2.71E-06 16 92 "CFLAR,BTK,CACNA1A,EZH1,PRMT5,FOXF2,GGT5,FAM107A,AFDN,SETD4,PDPK1,SBF1,STUM,USP22,HNRNPA3,GJC2" MicroRNA hsa-miR-3065-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-07 1.12E-03 2.99E-07 2.75E-06 19 128 "SPATA2,MYEF2,RAB39B,FCF1,ZNF585B,TUBGCP4,IGF1,ZNF678,ITPKB,NCAM2,POLG,SNRK,PEX2,PRRT2,SEC31A,TET1,SYPL1,RPL7L1,SPATA13" MicroRNA hsa-miR-4710:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-07 1.15E-03 3.06E-07 2.82E-06 21 154 "TXNDC16,AK2,ARRB2,CFL2,PPP1R16B,SEC16A,DNAH9,EDN1,ANKFY1,PDLIM5,SEPT9,POLL,SHISAL1,MORC4,KCNIP3,EPN2,SP2,TPM2,ZNF70,ACTR3B,GAN" MicroRNA hsa-miR-3978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-07 1.18E-03 3.14E-07 2.89E-06 18 116 "AK2,HAPLN1,DCAF8,TMEM170A,EGR3,C8orf37,SUCO,SYNCRIP,GPR137C,PDPK1,PLEC,PSAT1,PGBD4,ATXN7,CPEB3,SLC8A1,TUBB2A,HNRNPA3" MicroRNA hsa-miR-3655:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-07 1.18E-03 3.14E-07 2.89E-06 11 42 "XKR4,SOCS5,FEM1B,HEYL,GPR75,PIGG,PTGR2,GALNT10,WDR37,FAIM2,ZNF28" MicroRNA "CCCACAT,MIR-299-3P:MSigDB" "CCCACAT,MIR-299-3P:MSigDB" MSigDB 2.14E-07 1.20E-03 3.19E-07 2.93E-06 12 51 "ADD1,RUNX1T1,TMEM35A,RABEPK,AGBL5,GIT1,SP4,IQSEC2,PDLIM2,TCF4,UBE2H,PLEKHH2" MicroRNA hsa-miR-676-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-07 1.20E-03 3.19E-07 2.93E-06 12 51 "RNF157,UBXN2A,CCDC144A,E2F6,IL6ST,SEPT4,RPL15,ARMH4,ZMAT3,RPL7L1,VLDLR,ZNF24" MicroRNA hsa-miR-1228-3p:Functional MTI Functional MTI miRTarbase 2.17E-07 1.21E-03 3.23E-07 2.97E-06 28 254 "APAF1,ATP1B3,CA8,PLAA,STOML1,EDIL3,EPB41,SLC43A2,MRPL10,TLR7,CEP78,POLR1B,FOXF2,FOXO3,MSANTD4,ZNF274,FAM107A,ITPKB,PPM1L,AFF1,ZC3H12B,APTX,PTPRN2,NWD1,DCUN1D2,SEPHS1,NFASC,ZSCAN29" MicroRNA hsa-miR-3190-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-07 1.26E-03 3.34E-07 3.07E-06 30 285 "KIAA1324,APAF1,CBS,CCNT1,CTH,GREB1,DBT,YTHDC1,MRO,ZNF549,GLUL,LUZP2,FICD,SAMD5,SFR1,SLC11A2,MINDY2,PTPRB,ZNF793,SNX22,PREX2,UNC5B,NEK4,USP22,ZMAT3,ZNF610,TBC1D15,ZNF708,ZNF70,URM1" MicroRNA hsa-miR-6823-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-07 1.26E-03 3.36E-07 3.09E-06 14 71 "HECW2,LONRF2,SPATA2,C2CD2L,TMCC2,MTSS1L,CELF1,TDRKH,KAT7,NEGR1,NCR3LG1,ATXN2,PKNOX2,PEG10" MicroRNA hsa-miR-4645-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-07 1.26E-03 3.36E-07 3.09E-06 14 71 "MARCH4,ARRB2,SPATA2,RPS6KL1,HIPK3,RASGRP1,AMOTL2,B4GALNT1,SRCAP,MYO5A,ZNF354C,RMI1,SLC30A4,WNK3" MicroRNA hsa-miR-6859-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-07 1.27E-03 3.36E-07 3.09E-06 23 182 "CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,PYGO1,IP6K1,DBN1,AMOTL2,AFF2,CELF1,IDH3A,MID1,FIGN,ELP2,TRIM67,COA1,DIP2A,SATB2,HIF3A,TUBB2A,WRN,ITM2C" MicroRNA hsa-miR-6811-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-07 1.27E-03 3.36E-07 3.09E-06 23 182 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,AKAP5,GREB1,DNAL1,YTHDC1,TRAF3IP2,RAB30,IGF1,KCNJ5,ZC3H12B,PEX2,NCBP3,SH3BP2,INAVA,UNC5B,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA hsa-miR-6843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-07 1.29E-03 3.42E-07 3.15E-06 26 225 "TMEM132B,ATP1B3,MTMR3,STOML1,MYADM,SV2B,NR1D2,MTSS1L,MRPL37,ZNF585B,CELF1,DDX19B,MAN2A2,MYO5A,MYO6,SKOR1,ZSCAN2,ZMAT4,DCUN1D2,KLHDC8A,SGSM1,FAM126B,ERBIN,ZNF34,SGK3,MSRB3" MicroRNA hsa-miR-6848-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-07 1.29E-03 3.42E-07 3.15E-06 26 225 "TMEM132B,ATP1B3,MTMR3,STOML1,MYADM,SV2B,NR1D2,MTSS1L,MRPL37,ZNF585B,CELF1,DDX19B,MAN2A2,MYO5A,MYO6,SKOR1,ZSCAN2,ZMAT4,DCUN1D2,KLHDC8A,SGSM1,FAM126B,ERBIN,ZNF34,SGK3,MSRB3" MicroRNA hsa-miR-6087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-07 1.30E-03 3.44E-07 3.16E-06 29 270 "ELFN2,TXNDC16,TRMT9B,ASPA,CDR1,PLAA,NCOR2,MYADM,SLC29A4,ABCC5,FECH,GCK,GNG4,KAT7,IGF1,ZNF713,RBBP8,C12orf49,PTGR2,FNIP1,SEPHS1,FNBP1,PEG10,MCF2L2,CLASP1,SSBP2,USP1,ZNF708,EVI5" MicroRNA hsa-miR-6820-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.34E-07 1.31E-03 3.47E-07 3.20E-06 13 61 "FMNL2,ELFN2,USP37,CA12,APPL1,TRMO,TJAP1,IL6ST,POLR2F,PEX26,ZFP1,LIMCH1,ZXDA" MicroRNA hsa-miR-642a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-07 1.33E-03 3.53E-07 3.25E-06 15 82 "CACNA1B,CDC25B,FOXN3,KIAA0408,MTX3,EXOG,SYNCRIP,MPP2,PDE4D,OXR1,PNMA8A,NCBP3,PPP4R3A,USP22,BHLHB9" MicroRNA hsa-miR-642b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-07 1.33E-03 3.53E-07 3.25E-06 15 82 "CACNA1B,CDC25B,FOXN3,KIAA0408,MTX3,EXOG,SYNCRIP,MPP2,PDE4D,OXR1,PNMA8A,NCBP3,PPP4R3A,USP22,BHLHB9" MicroRNA hsa-miR-3925-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-07 1.35E-03 3.56E-07 3.28E-06 18 117 "PHF12,IGDCC4,CLDN10,BAG4,SLC37A3,CELF1,ST6GALNAC3,CRCP,TNRC6A,CNOT4,ZIK1,NWD1,MORC4,RNASEL,ELP2,NR2E1,TSN,SPIRE1" MicroRNA hsa-miR-1185-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-07 1.35E-03 3.56E-07 3.28E-06 18 117 "ZNF608,VAT1L,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,NCOA7,MBNL1,PCSK1,PFKFB2,TMEM104,KIF13A,DIP2A,GPRIN3,USP1" MicroRNA hsa-miR-511-5p:Functional MTI Functional MTI miRTarbase 2.43E-07 1.36E-03 3.60E-07 3.31E-06 17 105 "TNRC6C,CA8,BAG4,PITPNM3,DPP6,FEM1B,FRY,SRRM4,KAT7,RASSF8,KIAA1755,KCNN3,KSR2,GLIPR1L2,PGBD4,PCDHA6,ZNF711" MicroRNA hsa-miR-3074-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-07 1.36E-03 3.60E-07 3.31E-06 17 105 "ADD1,ABCD2,TNRC6C,PRX,ARSE,THSD7A,LRRFIP1,IRAK4,DLC1,UFM1,PDLIM5,LILRA2,KPNA5,MTRF1L,SP4,EXOC7,ZNF138" MicroRNA hsa-miR-3125:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-07 1.40E-03 3.70E-07 3.41E-06 23 183 "CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,PYGO1,IP6K1,DBN1,AMOTL2,AFF2,CELF1,IDH3A,MID1,FIGN,ELP2,TRIM67,COA1,DIP2A,SATB2,HIF3A,TUBB2A,WRN,ITM2C" MicroRNA hsa-miR-3120-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-07 1.44E-03 3.80E-07 3.50E-06 21 156 "CDC14B,ARSE,ZNF555,PITPNM3,PLCXD3,GAPVD1,RASSF2,SGSM2,KATNAL1,TRAF3IP2,POLL,SYTL4,LSAMP,N6AMT1,KSR2,GLIPR1L2,PDE3A,BDP1,ADAMTS17,EXOC7,ZDHHC20" MicroRNA hsa-miR-1913:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-07 1.44E-03 3.81E-07 3.51E-06 19 130 "LRFN1,TOGARAM2,CPS1,YTHDC1,MRPL37,SEC24B,SEC23B,KIAA1841,SRCAP,FAM107A,MAP4,MBD1,ZDHHC8,PIGG,KLHL11,HSPA4L,STAC2,KIAA0930,NACC2" MicroRNA hsa-miR-3165:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-07 1.44E-03 3.81E-07 3.51E-06 19 130 "TAOK1,NRXN3,USP6NL,GAPVD1,RASSF2,DUSP9,ZNF549,MRPL10,MTHFD2,LUZP2,GNG4,PPM1L,MKLN1,PLXNB1,CEP97,STUM,PEG10,SSBP2,EVI5" MicroRNA hsa-miR-4263:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-07 1.50E-03 3.97E-07 3.65E-06 16 94 "FZD9,ABCD2,SFMBT2,PTBP2,CRY2,SUCO,SARAF,GATM,GCK,ZHX1,HNF4G,NEGR1,KITLG,PKM,TET1,RGMB" MicroRNA hsa-miR-6866-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-07 1.50E-03 3.97E-07 3.65E-06 16 94 "SPOP,AQP6,CACNA1A,VXN,SLC16A4,SEC31B,ELMSAN1,TMTC1,PLEKHA1,KLHL23,MBNL1,CEP97,GTDC1,UBR7,GALNT10,KAT6A" MicroRNA hsa-miR-8081:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-07 1.50E-03 3.97E-07 3.65E-06 16 94 "OGT,DNAH17,CD86,USP6NL,LONRF1,ANKRD46,CELSR3,RNF165,SHMT2,ST6GAL1,SEPHS1,TMCC1,PDZD2,ERBIN,CYB561A3,JMJD1C" MicroRNA hsa-miR-99b-5p:TargetScan hsa-miR-99b-5p TargetScan 2.74E-07 1.53E-03 4.05E-07 3.73E-06 11 43 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,AP1AR,SATB1" MicroRNA hsa-miR-99a-5p:TargetScan hsa-miR-99a-5p TargetScan 2.74E-07 1.53E-03 4.05E-07 3.73E-06 11 43 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,AP1AR,SATB1" MicroRNA hsa-miR-100-5p:TargetScan hsa-miR-100-5p TargetScan 2.74E-07 1.53E-03 4.05E-07 3.73E-06 11 43 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,AP1AR,SATB1" MicroRNA hsa-miR-1226-3p:Functional MTI Functional MTI miRTarbase 2.74E-07 1.53E-03 4.05E-07 3.73E-06 26 227 "NDRG3,ATP2A2,PLXNA4,LONRF1,TM9SF4,ELMO1,SACS,ERCC2,TBC1D16,DLC1,RACK1,FGFR1,FAM107A,SHISAL1,LIMS1,NDUFS7,ZDHHC4,PBRM1,ATXN2,TRIM67,ZNF106,CABIN1,USP1,ZNF781,ZNF154,ZNF195" MicroRNA hsa-miR-574-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-07 1.55E-03 4.08E-07 3.76E-06 9 27 "USP31,CLTC,IGLON5,EGFR,CPLX2,MUM1,C2orf72,RXRA,PDZD2" MicroRNA hsa-miR-637:Functional MTI Functional MTI miRTarbase 2.79E-07 1.56E-03 4.13E-07 3.80E-06 17 106 "TAOK1,PRX,ARHGDIA,BMP7,METTL6,ZNF385A,IP6K1,RASA4,KCNH2,CHST6,PKM,SBF1,GALNT10,FNBP1,UNC5B,USP22,CLASP1" MicroRNA hsa-miR-5195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-07 1.57E-03 4.14E-07 3.81E-06 15 83 "SMIM17,THSD7A,ZNF445,UBXN2A,NR1D2,EID2B,ZNF678,ZNF426,PNMA3,PSAT1,UBR7,ALG9,CSRNP3,CLSTN2,ANKRD28" MicroRNA hsa-miR-6728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-07 1.57E-03 4.14E-07 3.81E-06 15 83 "BACH1,CDC25B,CLOCK,SEC24C,DCAF8,DNAL1,GLUL,PRRC2B,STMN1,CHST6,MINDY2,STX1B,GALNT10,STAU1,NSD1" MicroRNA hsa-miR-4502:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.86E-07 1.60E-03 4.22E-07 3.89E-06 13 62 "FZD9,INTS2,ANKRD44,RUSC2,CHST15,SYNCRIP,SMC2,KPNA5,MMP16,PDE4D,TMEM200C,MBD5,ZNF708" MicroRNA "GACAGGG,MIR-339:MSigDB" "GACAGGG,MIR-339:MSigDB" MSigDB 2.86E-07 1.60E-03 4.22E-07 3.89E-06 13 62 "HAP1,PPP6R2,C3orf18,EMX2,FHL1,FLT1,ABLIM2,ATXN2L,NNAT,NOVA1,NFASC,THRA,UBE3A" MicroRNA hsa-miR-204-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-07 1.63E-03 4.29E-07 3.95E-06 19 131 "RGS6,ASB3,VPS26C,AMOTL2,MTHFD2,CRCP,GLUL,POLL,LILRA2,BVES,NEGR1,KCTD15,KIAA0895L,PEX26,NFASC,NXT2,CBX5,BHLHB9,ZBTB38" MicroRNA hsa-miR-143-3p:Functional MTI Functional MTI miRTarbase 2.99E-07 1.67E-03 4.41E-07 4.06E-06 26 228 "MTA3,OSBPL8,CDC25B,DBT,JAKMIP2,DTNB,PLEKHA1,GLUL,PRRC2B,KAT7,MIER3,CREG2,MYO6,PIK3R1,ZNF426,PPP2R5E,MAPK7,ELP2,SCN2B,FAM102A,NUBPL,KIAA0930,NR2C2,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-744:PITA hsa-miR-744:PITA_TOP PITA 3.08E-07 1.73E-03 4.54E-07 4.18E-06 10 35 "UNC5A,ZNF385A,IP6K1,PHC2,GRIN2D,CAMK2N2,NFIX,ZNF827,PPP5C,SZT2" MicroRNA hsa-miR-3620-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-07 1.75E-03 4.60E-07 4.23E-06 16 95 "LRFN1,C6orf89,ZNF445,MTX3,AMOTL2,FOXF2,SMC2,SRCAP,ELOVL5,SYNPO,KCNN3,PDE4A,PKD1,CLASP1,ZMAT3,GALNT17" MicroRNA hsa-miR-6754-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.21E-07 1.80E-03 4.73E-07 4.35E-06 17 107 "STOML1,SUSD5,DOCK4,GAPVD1,CENPL,NR1D2,STARD3NL,DLC1,CELF1,KPNA5,SYTL4,TMOD2,SCN8A,ZC3H13,CYB561A3,ZNF138,ZNF195" MicroRNA hsa-miR-411-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-07 1.81E-03 4.77E-07 4.40E-06 14 73 "CCDC74A,ATP1B3,FSD1L,TUBD1,SCML2,MMADHC,SH3TC2,ALG9,PGBD4,FBXW7,SYPL1,FAM182B,FXR1,NETO2" MicroRNA hsa-miR-548ag:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-07 1.81E-03 4.77E-07 4.40E-06 14 73 "CALM1,PTBP2,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-3653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.28E-07 1.84E-03 4.83E-07 4.45E-06 19 132 "TAOK1,ZBTB10,BAG4,EIF4G2,TENM1,ACSL4,MIER3,LIFR,NCAM2,GDPD1,ZIK1,CEP97,SETD5,TRAPPC13,BTBD7,PEG10,UGT8,MPPE1,FZD3" MicroRNA hsa-miR-4324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.32E-07 1.86E-03 4.89E-07 4.50E-06 22 172 "ELFN2,RNF157,BACH1,CDC25B,TMEM184B,ZNF385A,CPS1,SIGLEC8,ZNF638,ZDHHC15,SLC35G1,METTL21A,CHIC1,P2RX7,ZNF426,COPZ1,PEX26,ZNF106,RPL7L1,ZNF177,TMEM198,STOX2" MicroRNA hsa-miR-548l:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.32E-07 1.86E-03 4.89E-07 4.50E-06 22 172 "SORCS2,BACH1,CPS1,RAB39B,KATNAL1,MTHFD2,IL6ST,ZNF678,CHST6,MKLN1,PPP2R5E,REV3L,ALG9,ZNF354C,ATF7IP,ZBTB43,ATMIN,PCDHA6,ARL10,NACC2,UBE2H,ZNF711" MicroRNA hsa-miR-4474-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-07 1.95E-03 5.13E-07 4.72E-06 13 63 "BRAP,CFAP410,CRY2,SOCS5,LIN54,DMTF1,PRRC2B,RBPJ,ZNF678,ALDH1L2,NOVA2,MRPS18A,ZNF331" MicroRNA hsa-miR-331-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-07 1.95E-03 5.13E-07 4.72E-06 13 63 "FAM135A,TNRC6C,E2F6,CELF1,IL6R,SLC35G1,LIFR,MYCN,SNX10,PPP1R1A,SAFB,BTBD3,AP4E1" MicroRNA hsa-miR-4694-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.55E-07 1.99E-03 5.21E-07 4.80E-06 18 120 "OGT,LDHD,WASF1,CPS1,PYGO1,FEM1B,SCML2,SYNCRIP,MSANTD4,MAT2A,MBNL1,PKM,REV3L,SLC6A8,ZSCAN29,TLR4,LRRC8A,FXR1" MicroRNA hsa-miR-3916:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.69E-07 2.07E-03 5.43E-07 4.99E-06 23 187 "CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,PYGO1,IP6K1,DBN1,AMOTL2,AFF2,CELF1,IDH3A,MID1,FIGN,ELP2,TRIM67,COA1,DIP2A,SATB2,HIF3A,TUBB2A,WRN,ITM2C" MicroRNA hsa-miR-1224-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.80E-07 2.12E-03 5.58E-07 5.13E-06 28 261 "AS3MT,MTA3,CACNA1A,ZBED1,GAPVD1,RIPOR2,ABCC5,TNK2,MRPL37,ANKFY1,ST6GALNAC3,SRCAP,HAS2,MAN2A2,TMOD2,PIK3C2A,ZNF426,PSAT1,KLHL11,GSTCD,KIF21A,FAM126B,STAC2,TCF12,NSD1,ZNF34,ZNF708,HNRNPA3" MicroRNA hsa-miR-1197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-07 2.16E-03 5.68E-07 5.23E-06 14 74 "TEX22,ATP1B3,KALRN,LONRF1,ZNF391,ANKFY1,ZSCAN2,SETD5,ATAT1,GALNT10,TRIM2,SLC44A1,UBTF,UGT8" MicroRNA hsa-miR-648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-07 2.16E-03 5.68E-07 5.23E-06 14 74 "SFMBT2,CALM1,EVI5L,SEC16A,EDN1,KATNAL1,MSANTD4,MALT1,XRRA1,QDPR,SGK1,MPRIP,MGRN1,ZNF138" MicroRNA hsa-miR-4682:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-07 2.16E-03 5.68E-07 5.23E-06 14 74 "RNF157,CPS1,PPP1R16B,SPATA2,RNF165,FICD,P2RX7,PDE4D,GRAMD1C,SLC25A36,SEMA6D,CHD9,FAM126B,NSD1" MicroRNA hsa-miR-3194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-07 2.17E-03 5.68E-07 5.23E-06 15 85 "SFMBT2,PRX,LDLRAD4,STOML1,TMEM184B,TOM1,APC2,ANKMY1,CELF1,LYVE1,STARD3,PRRT2,FAM192A,ZBTB43,DIP2A" MicroRNA hsa-miR-589-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-07 2.17E-03 5.68E-07 5.23E-06 15 85 "RASL11B,LRIG1,SCML2,FGF1,DOT1L,BDNF-AS,ZNF844,SETD5,RPL15,SEMA6D,DHX30,ZNF621,TBL1X,UBTF,ZNF189" MicroRNA hsa-miR-450b-3p:PITA hsa-miR-450b-3p:PITA_TOP PITA 3.87E-07 2.17E-03 5.68E-07 5.23E-06 15 85 "CLDN10,USP6,MYEF2,APH1A,FAM19A2,HLF,MEIS2,MKLN1,NOVA1,NPTX1,PBRM1,CCDC92,WDR47,LARP4,INTS3" MicroRNA hsa-miR-720:PITA hsa-miR-720:PITA_TOP PITA 3.94E-07 2.20E-03 5.77E-07 5.31E-06 8 21 "CACNA1A,HECTD1,AGAP2,MSI1,KCTD15,ANKRD16,SST,SLC44A1" MicroRNA hsa-miR-3157-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-07 2.25E-03 5.90E-07 5.44E-06 18 121 "SORCS2,PCDHGB4,SLC2A11,HINFP,EXOG,WDPCP,TMTC1,MRO,LYVE1,POLL,DIDO1,RDX,HUNK,ZFP30,SNAP25,DIP2A,ZNF711,GAN" MicroRNA hsa-miR-487a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "CLTC,ABCG2,MMP16,PIK3R1,KANSL1,FIGN,MCMBP,CPEB4,MYCBP2,SYPL1,INTS3,ACTR3B" MicroRNA hsa-miR-1295:mirSVR_highEffct hsa-miR-1295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "ABHD6,ZNF583,CBS,RAB28,EGR3,MATN2,MBD1,EPB41L4B,RBBP6,LRFN5,FHOD3,TRO" MicroRNA hsa-miR-4674:Functional MTI Functional MTI miRTarbase 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "ARHGDIA,IPCEF1,RIPOR2,RUSC2,ZMAT1,ITPKB,NPTX1,HKR1,SETD5,SLC6A8,BDP1,TUBB2A" MicroRNA hsa-miR-1298-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "AK2,EDN1,KLHL5,ACSL4,TMEM107,SYNPO,SHISA6,NR2E1,TSC1,ZNF70,SIGLEC10,FXR1" MicroRNA hsa-miR-617:Non-Functional MTI Non-Functional MTI miRTarbase 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "TMEM132B,HECW2,CCPG1,MRPL37,INSYN1,THYN1,NTRK3,MYH15,LIMCH1,NECAB1,CBX5,URM1" MicroRNA hsa-miR-208a-3p:Functional MTI Functional MTI miRTarbase 4.18E-07 2.34E-03 6.12E-07 5.64E-06 12 54 "AXIN2,QKI,LIN54,DGKG,CPEB2,CELF1,IQGAP2,MAPK10,ZNF844,ASAP3,AMBRA1,TUBB2A" MicroRNA hsa-miR-92a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-07 2.34E-03 6.13E-07 5.64E-06 27 247 "CASKIN1,ARRB1,BCL7A,CAMK2A,IP6K1,APH1A,MRNIP,DOT1L,MTHFD2,GFER,RNPS1,GLI2,PRRC2B,SHISA6,SOWAHA,KCNN3,NFIX,TBC1D25,GPR173,PKM,NLE1,PEX26,PKNOX2,SPART,ARC,CLASP1,RICTOR" MicroRNA hsa-miR-4705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.23E-07 2.37E-03 6.19E-07 5.70E-06 13 64 "BMPR1B,ZNF555,ZMYM4,DBT,VPS13B,MTSS1L,MIER3,USP51,IBA57,NLGN1,KANSL3,DICER1,AMACR" MicroRNA hsa-miR-363-3p:Functional MTI Functional MTI miRTarbase 4.33E-07 2.42E-03 6.34E-07 5.84E-06 33 342 "CASKIN1,ADAM15,TMEM184B,MRO,PLEKHA1,EIF1,KIAA1958,PRRC2B,LILRA2,TPPP,AGBL5,EID2B,ZIC5,RBPJ,IL6ST,CNOT4,CCSER2,ZFYVE21,PURG,TATDN3,MTMR10,REV3L,SLC25A36,FBXW7,FNIP1,CPEB3,ATF7IP,CPEB4,SOX11,MCF2L2,ITPRID2,ZNF24,MFF" MicroRNA hsa-miR-3919:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-07 2.45E-03 6.41E-07 5.90E-06 21 161 "INTS2,MTUS1,BCAS1,CDC14B,ARHGEF7,CLDN10,CELF1,MSANTD4,COPS8,TNRC6A,KIAA1755,CREG2,PDPK1,NLE1,RNASEL,SGK1,ZFP30,FAM126B,PDZD2,STX1A,NACC2" MicroRNA hsa-miR-518a-5p:Functional MTI Functional MTI miRTarbase 4.38E-07 2.45E-03 6.41E-07 5.90E-06 21 161 "GAS7,EPHB1,ACSL4,TNRC6A,PRRC2B,PRUNE2,MAPT,KITLG,PIK3C2A,KCTD15,PLEC,PEX26,ATF7IP,ATMIN,ZMAT3,NACC2,TUBB2A,ZBTB38,SLC30A4,ZXDA,HNRNPA3" MicroRNA hsa-miR-27a-5p:Functional MTI Functional MTI miRTarbase 4.52E-07 2.53E-03 6.61E-07 6.09E-06 11 45 "ADD1,EGFR,UFM1,ZMAT1,POLL,MXI1,NPTX1,PPARA,SPIN3,SNAP25,TUBB2A" MicroRNA hsa-miR-4650-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-07 2.54E-03 6.62E-07 6.10E-06 15 86 "RNF157,DDR1,IP6K1,YTHDC1,ELMSAN1,PHC2,DNAJC27,MTHFD2,GGT7,FUT10,TJAP1,PKM,NSFL1C,ZC3H4,CBX5" MicroRNA hsa-miR-769-3p:PITA hsa-miR-769-3p:PITA_TOP PITA 4.53E-07 2.54E-03 6.62E-07 6.10E-06 15 86 "CLDN10,USP6,MYEF2,APH1A,FAM19A2,HLF,MEIS2,MKLN1,NOVA1,NPTX1,PBRM1,CCDC92,WDR47,LARP4,INTS3" MicroRNA hsa-miR-4742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-07 2.55E-03 6.66E-07 6.13E-06 18 122 "SLC2A11,KLHL3,DCTN4,COQ7,SMC2,SRRM4,LILRA2,NEGR1,LSAMP,KANSL1,PRKCB,TMLHE,EPC1,MYCBP2,FAM208A,TLR4,CLDND1,ZFAND5" MicroRNA hsa-miR-5694:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-07 2.55E-03 6.66E-07 6.13E-06 18 122 "HECW2,HACE1,AQP6,CBR1,CBFA2T2,ZNF385A,TMEM170A,MRNIP,MSL1,SLC11A2,STK32A,ZNF844,SH3TC2,FBXW7,FAM208A,ZNF610,RPL7L1,ZFP37" MicroRNA hsa-miR-496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-07 2.55E-03 6.66E-07 6.13E-06 18 122 "BACH1,CD86,CPS1,SMC2,ZIC5,SFXN5,NPTX1,SNX10,ZNF426,NKAIN1,ZNF793,SH3TC2,TMLHE,PEX26,TMCC1,MYCBP2,TACC1,ZFAND5" MicroRNA hsa-miR-6830-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.59E-07 2.57E-03 6.70E-07 6.17E-06 14 75 "SLC24A4,IGDCC3,PLXNA4,ZNF391,NEU3,ZNF496,ITPKB,MITF,PTPRB,TMEM231,TMCC1,AGTPBP1,SLC44A1,CLDND1" MicroRNA hsa-miR-374a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.59E-07 2.57E-03 6.70E-07 6.17E-06 14 75 "AXIN2,ZBTB10,FOXN3,C8orf37,SMC2,PLCL1,SEMA6D,CSRNP3,SGK1,ZMAT3,ZNF106,ZNF154,TFIP11,PARP11" MicroRNA hsa-miR-1911-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.59E-07 2.57E-03 6.70E-07 6.17E-06 14 75 "DNAH17,ATP1A1,DBT,PHC2,PRRC2B,PALM,PDE4A,SEPT4,QDPR,ALG9,TRIM67,ZNF106,TMEM237,GAN" MicroRNA "TTGGAGA,MIR-519E:MSigDB" "TTGGAGA,MIR-519E:MSigDB" MSigDB 4.68E-07 2.62E-03 6.82E-07 6.28E-06 19 135 "NCOA1,SLC4A4,OSBPL3,PUM1,POM121,CPEB2,YAF2,EMX2,ETV1,GABBR1,KCND2,MSI1,SCN8A,EPN2,SNAP25,SP4,CLSTN2,TACC1,UBE2H" MicroRNA "TTGGAGA,MIR-515-5P:MSigDB" "TTGGAGA,MIR-515-5P:MSigDB" MSigDB 4.68E-07 2.62E-03 6.82E-07 6.28E-06 19 135 "NCOA1,SLC4A4,OSBPL3,PUM1,POM121,CPEB2,YAF2,EMX2,ETV1,GABBR1,KCND2,MSI1,SCN8A,EPN2,SNAP25,SP4,CLSTN2,TACC1,UBE2H" MicroRNA hsa-miR-4457:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.82E-07 2.70E-03 7.02E-07 6.46E-06 17 110 "TXNDC16,ZNF555,TOGARAM2,GREB1,TM9SF4,SYTL4,ZNF713,P2RY1,PDE4D,PCMTD2,CSRNP3,POGZ,DIP2A,IQCE,NSD1,SLC38A1,GAN" MicroRNA hsa-miR-4291:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.84E-07 2.71E-03 7.04E-07 6.49E-06 16 98 "ELFN2,RUBCN,MAML1,FEM1B,HEYL,FAM13A,FAM49B,MTHFD2,DISC1,KCTD15,CPEB4,SLC37A2,TUBB2A,RPL7L1,ZNF45,GDPD5" MicroRNA hsa-miR-4450:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.11E-07 2.86E-03 7.44E-07 6.85E-06 13 65 "PPFIA4,ARRB2,KLHL3,TMCC2,APH1A,DLC1,KCNN3,SLC25A23,BTBD3,MPRIP,CLIP2,LAT2,CIAPIN1" MicroRNA hsa-miR-548av-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "MARCH4,BACH1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,IL6ST,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-6752-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,RICTOR,ZDHHC20" MicroRNA hsa-miR-7110-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,RICTOR,ZDHHC20" MicroRNA hsa-miR-6842-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,RICTOR,ZDHHC20" MicroRNA hsa-miR-8054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "MARCH4,BACH1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,IL6ST,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-548k:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-07 2.88E-03 7.47E-07 6.88E-06 20 149 "MARCH4,BACH1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,IL6ST,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-4795-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.17E-07 2.89E-03 7.51E-07 6.91E-06 18 123 "CNRIP1,CSNK1G3,SLC12A6,FOXO3,FYB1,TNRC6A,ZNF638,GRIK5,IL6R,MYCN,NPTX1,SNX10,SETD5,CSRNP3,MYCBP2,CBX5,NR2C2,ZXDA" MicroRNA hsa-miR-330-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.17E-07 2.89E-03 7.51E-07 6.91E-06 18 123 "SORCS2,ARHGDIA,ARRB2,BMP7,MYRF,IP6K3,MTHFD2,BVES,PDE3A,PDE4B,PDE1B,PKM,BCAS3,STX1B,STUM,MYH15,SSBP2,ZNF154" MicroRNA hsa-miR-34b-5p:Functional MTI Functional MTI miRTarbase 5.17E-07 2.89E-03 7.51E-07 6.91E-06 18 123 "AXIN2,SHROOM2,ZNF582,EVI5L,UBXN2A,EBI3,VTI1B,NEURL4,MALT1,FERMT2,ZNF546,MAP4,MYCN,CNOT4,POLR2F,TROVE2,ZSCAN29,ZNF708" MicroRNA hsa-miR-22-3p:Functional MTI Functional MTI miRTarbase 5.40E-07 3.02E-03 7.84E-07 7.21E-06 21 163 "NCOA1,BMP7,BMPR1B,FUBP1,RBM39,CSF1R,HDAC4,ERBB2,IBA57,MYO6,DNHD1,NTRK2,PIK3C2A,PPARA,CHD9,TACC1,SIRT1,TIAM1,ELP5,VSNL1,HNRNPA3" MicroRNA hsa-miR-5696:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.40E-07 3.02E-03 7.84E-07 7.21E-06 21 163 "BRAP,KIAA1211,CDK13,CALM1,APPL1,TENM1,EPHB1,FUT9,KIAA1841,INSYN1,KCTD15,MAGEL2,PKIA,RNASEL,TMLHE,CCDC25,ZNF331,TRAPPC13,CSRNP3,TROVE2,ZFP37" MicroRNA hsa-miR-5010-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.40E-07 3.02E-03 7.84E-07 7.21E-06 21 163 "TNRC6C,CCPG1,CLOCK,CSNK1G3,JAKMIP2,ZC3H11A,DMD,FGF14,DOT1L,CBX1,AP4S1,IPO5,HECTD2,HS6ST3,PDPK1,REV3L,CLIP1,MPRIP,ASTN2,ZEB1,VSNL1" MicroRNA hsa-miR-4778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-07 3.05E-03 7.90E-07 7.28E-06 14 76 "CPS1,SOCS5,JAKMIP2,RAB39B,IL6ST,LSAMP,NCAM2,GTDC1,CSRNP3,TET1,EPC1,ZHX3,ZBTB38,CADM2" MicroRNA hsa-miR-604:PITA hsa-miR-604:PITA_TOP PITA 5.53E-07 3.10E-03 8.03E-07 7.39E-06 9 29 "CAMK2G,DCLK1,ZNF521,RIMS4,TAOK3,GRIK5,CAMK2N2,MSI1,ARX" MicroRNA hsa-miR-4426:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-07 3.12E-03 8.08E-07 7.44E-06 16 99 "SLC24A4,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,CHST6,PPARA,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-4647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-07 3.12E-03 8.08E-07 7.44E-06 16 99 "SLC24A4,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,CHST6,PPARA,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-4662b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-07 3.12E-03 8.08E-07 7.44E-06 16 99 "SLC24A4,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,CHST6,PPARA,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-196b-5p:Functional MTI Functional MTI miRTarbase 5.73E-07 3.21E-03 8.30E-07 7.65E-06 20 150 "BRAP,MTUS1,FAM135A,IGDCC4,BACH1,CALM1,LHX2,DCTN4,RACK1,SARAF,PRUNE2,SLC35G1,PAXBP1,MAT2A,MEIS1,PPARA,RDX,ARMH4,KIF27,HSPA4L" MicroRNA hsa-miR-4774-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.75E-07 3.22E-03 8.34E-07 7.68E-06 11 46 "LONRF2,RBPJ,KIT,LIMS1,MAT2A,ZNF426,PTPRE,ZNF793,C12orf49,ZNF781,MPPE1" MicroRNA hsa-miR-4691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.84E-07 3.27E-03 8.46E-07 7.79E-06 18 124 "SORCS2,PCDHGB4,SLC2A11,TMTC1,MRO,ANKMY1,GABRB3,LYVE1,GLYR1,PTCH1,TTC13,RDX,HUNK,ZFP30,DIP2A,SYT5,UBE2H,ZNF711" MicroRNA hsa-miR-4651:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.92E-07 3.31E-03 8.57E-07 7.89E-06 23 192 "ARHGDIA,CRLF1,ZNF385A,IP6K1,SGSM2,ELN,MTSS1L,ANKFY1,GLI2,POLL,PRRC2B,KCNK3,MPP2,ZC3H12B,PKM,PLEC,PPARA,MAPK10,KLHDC8A,ATXN2,UNC5B,SEPT8,UBTF" MicroRNA hsa-miR-3127-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-07 3.34E-03 8.66E-07 7.97E-06 21 164 "ASGR1,CBS,NUMBL,CYBB,IP6K1,KIAA0319,KLHL5,PHF20L1,STARD3NL,REEP2,CELF1,GALC,KCNMB4,METTL21A,STMN1,LSAMP,POU6F1,GTDC1,TMLHE,KIRREL1,LAT2" MicroRNA hsa-miR-15b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.15E-07 3.44E-03 8.91E-07 8.20E-06 13 66 "ABCD2,CACNA1B,BACH2,ZC3H12B,RETREG2,CNTLN,GTDC1,KIAA0895L,MCMBP,CSRNP3,ITPRID2,ZNF708,ZNF28" MicroRNA hsa-miR-2116-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.15E-07 3.44E-03 8.91E-07 8.20E-06 13 66 "TNRC6C,C1orf52,YTHDC1,RCAN1,GOLT1B,YAF2,ERBB2,STAMBP,NCKAP1L,XRRA1,NCAM2,PDE3A,SH3TC2" MicroRNA hsa-miR-3614-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.15E-07 3.44E-03 8.91E-07 8.20E-06 13 66 "ADD1,PDE4DIP,PPP1R16B,FAM131B,CDON,TXNL4A,LIFR,CHST6,NPTX2,GPR137C,PDE3A,BDP1,ANKRD28" MicroRNA hsa-miR-367-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-07 3.45E-03 8.91E-07 8.21E-06 32 331 "CASKIN1,TMEM184B,MRO,PLEKHA1,EIF1,KIAA1958,PRRC2B,LILRA2,TPPP,AGBL5,EID2B,ZIC5,RBPJ,IL6ST,CNOT4,CCSER2,ZFYVE21,PURG,TATDN3,MTMR10,REV3L,SLC25A36,FBXW7,FNIP1,CPEB3,ATF7IP,CPEB4,SOX11,MCF2L2,ITPRID2,ZNF24,MFF" MicroRNA hsa-miR-493-3p:Functional MTI Functional MTI miRTarbase 6.17E-07 3.45E-03 8.92E-07 8.22E-06 15 88 "KIF1A,CALM1,SRSF11,PDE4DIP,SLC43A2,CELF1,NXPH3,ZNF678,LIFR,MAP2,MXI1,PEX2,MYCBP2,SSBP2,VLDLR" MicroRNA hsa-miR-1234:mirSVR_highEffct hsa-miR-1234:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.17E-07 3.45E-03 8.92E-07 8.22E-06 15 88 "RGS9,ENTPD4,CRMP1,PTK2B,MASP1,RPL15,ARMH4,SCN8A,TNFRSF19,FUZ,BTBD3,TTC17,ZC3H4,EMSY,MPPE1" MicroRNA hsa-miR-4738-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-07 3.50E-03 9.05E-07 8.33E-06 17 112 "FZD9,NUMB,SRSF11,C2CD2,SEC14L5,PTPRT,FICD,IL6R,SH3TC2,MBD5,MCF2L2,DDN,NEK4,KLHL7,TLR4,ZFAND5,MFF" MicroRNA hsa-miR-3914:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.37E-07 3.56E-03 9.20E-07 8.47E-06 12 56 "SLC24A4,TMEM170A,DBN1,ZNF461,ADAM28,ITPKB,KIF5A,LAMP2,GPR137C,PKD1,SLC2A5,GAN" MicroRNA hsa-miR-548b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-07 3.60E-03 9.29E-07 8.55E-06 14 77 "ISPD,PRC1,CLCN3,SPATA2,RCAN1,NBEA,PRRC2B,GRIK4,AFF1,SALL1,SATB1,MYO16,TST,TFIP11" MicroRNA hsa-miR-6769a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-07 3.60E-03 9.29E-07 8.55E-06 14 77 "XKR4,TEX22,LONRF2,REEP2,MSANTD4,METTL21A,STMN1,MMP17,NEXMIF,VWA2,STX1B,SCN7A,RPL7L1,DPYSL5" MicroRNA hsa-miR-4662a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-07 3.60E-03 9.29E-07 8.55E-06 14 77 "CALM1,AMOTL2,IGF1,KPNA5,CCSER2,PURG,PPP2R5E,ZNF793,CNKSR2,ZBTB43,ERBIN,NR2E1,TUBB2A,SPIRE1" MicroRNA hsa-miR-4761-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-07 3.60E-03 9.29E-07 8.55E-06 14 77 "ABCF1,AS3MT,BRAP,ATP1B3,ARHGEF4,MRO,ANKFY1,FREM1,GNAL,MBD1,CCSER2,TMCC1,TBL1X,FXR1" MicroRNA hsa-miR-326:Functional MTI Functional MTI miRTarbase 6.61E-07 3.70E-03 9.54E-07 8.78E-06 19 138 "SORCS2,BMP7,SRRM1,ERBB2,FGF1,MTHFD2,BVES,ATXN2L,MAT2A,PDE3A,PDE1B,PKM,BCAS3,VPS13C,STUM,MYH15,SSBP2,ZNF154,JMJD1C" MicroRNA hsa-miR-4729:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-07 3.70E-03 9.54E-07 8.78E-06 19 138 "KIAA1211,KCTD16,ARHGDIA,CALM1,MYADM,DBN1,SYNCRIP,SMC2,KIAA1841,IL6ST,LIMS1,KCTD15,TMLHE,ZNF331,CSRNP3,GPRIN3,TNS1,ZFP37,ZNF138" MicroRNA hsa-miR-378a-3p:Functional MTI Functional MTI miRTarbase 6.62E-07 3.70E-03 9.55E-07 8.79E-06 21 165 "ESYT2,DPY19L3,KSR1,MYRF,IGDCC3,E2F5,HIPK3,DCTN4,MRPL37,ACSL4,RNPS1,NME4,OCRL,CHAMP1,VPS13C,CASC3,TRA2B,SEC31A,STXBP1,ZBTB14,CELF4" MicroRNA hsa-miR-6089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.64E-07 3.72E-03 9.58E-07 8.82E-06 22 179 "SLC24A4,TXNDC16,PDZD4,TRMT9B,DNAH17,HCN2,ISPD,EVI5L,GREB1,USP6NL,DNAL1,STX2,GNG4,ZNF491,NFIX,ZNF713,NLE1,RETREG2,PPARA,CEP97,KCNIP3,UHRF1BP1L" MicroRNA hsa-miR-760:Functional MTI Functional MTI miRTarbase 7.11E-07 3.98E-03 1.03E-06 9.44E-06 23 194 "CCAR2,ATP1B3,MAGED1,AKAP12,PUM1,PDCD6IP,GOLGA7,SRRM1,TUBA1B,FDFT1,ANKFY1,TPPP,ATXN2L,KPNA5,NPTX1,SMOX,WBP1L,SGSM1,SLC8A1,TRPS1,UBTF,WNK2,UBE3B" MicroRNA hsa-miR-4715-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.12E-07 3.99E-03 1.03E-06 9.45E-06 17 113 "ELFN2,MARCH3,RNF14,HINFP,SPATA2,AASDH,TMTC1,CELF1,SLC2A6,RBPJ,MAN2A2,NOVA2,SH3TC2,ATF7IP,RPL7L1,CFAP298,ZNF138" MicroRNA hsa-miR-580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.17E-07 4.01E-03 1.03E-06 9.52E-06 15 89 "TAOK1,LRCH2,ARHGEF7,CBS,CRY2,DNAL1,ACSL4,MED12L,NEU3,ZNF181,KCTD6,ZBTB43,POGZ,DHX33,KAT6A" MicroRNA hsa-miR-4670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.17E-07 4.01E-03 1.03E-06 9.52E-06 15 89 "MTA3,INTS2,PTBP2,MTHFD2,ATXN2L,BLOC1S2,MINDY2,TRA2B,FNDC3A,CPEB4,GPRIN3,ZKSCAN5,CLDND1,TFIP11,ZDHHC20" MicroRNA hsa-miR-4766-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.19E-07 4.02E-03 1.04E-06 9.53E-06 10 38 "SPATA2,CPEB2,SESN1,PTPRT,IL6ST,FIGN,KCNIP3,CLASP1,RGMB,GAN" MicroRNA hsa-miR-4791:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.19E-07 4.02E-03 1.04E-06 9.53E-06 10 38 "CA8,CDC25B,CELF1,KCNMB4,BACH2,PTPRD,CEP97,MBD5,PCDHA6,PARD3" MicroRNA hsa-miR-4418:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.36E-07 4.12E-03 1.06E-06 9.75E-06 16 101 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,BDP1" MicroRNA hsa-let-7c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.36E-07 4.12E-03 1.06E-06 9.75E-06 16 101 "JAZF1,CALM1,BAG4,DNAJB6,STARD3NL,IL6R,MMP16,PSD,FIGN,SEC14L1,TRA2B,FAM126B,NECAB1,PRRC2C,SLC44A1,CSMD1" MicroRNA hsa-miR-655-3p:Functional MTI Functional MTI miRTarbase 7.36E-07 4.12E-03 1.06E-06 9.75E-06 16 101 "NRP2,HIPK3,TMTC1,FAM69A,MID1,SATB1,TRIM67,TROVE2,EXOC7,ZEB1,TRIM2,TRPS1,ZNF610,TBC1D15,SPIRE1,ZDHHC20" MicroRNA hsa-miR-33b-5p:Functional MTI Functional MTI miRTarbase 7.36E-07 4.12E-03 1.06E-06 9.75E-06 16 101 "RNF157,KCTD16,SEMA7A,ZNF583,SOCS5,TMEM170A,EDN1,ACSL4,FER,CNOT4,PSAT1,ATF7IP,ZNF415,ZEB1,TNS1,REEP1" MicroRNA "GTGTGAG,MIR-342:MSigDB" "GTGTGAG,MIR-342:MSigDB" MSigDB 7.38E-07 4.13E-03 1.06E-06 9.77E-06 13 67 "PLPPR4,NBEA,CAMKK2,CCDC184,ATXN2L,MEIS1,MSI1,KLK6,PTPRN,SLC6A8,BTBD7,SEPT3,RICTOR" MicroRNA hsa-miR-6505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.58E-07 4.24E-03 1.09E-06 1.00E-05 14 78 "BBOX1,WASF1,SRSF11,RABEPK,STAMBP,BVES,KCNB1,NCAM2,RETREG2,REV3L,PCMTD2,FNDC3A,STOX2,KAT6A" MicroRNA hsa-miR-151-5p:PITA hsa-miR-151-5p:PITA_TOP PITA 7.65E-07 4.28E-03 1.10E-06 1.01E-05 9 30 "RALGAPA1,NRP2,RIMS4,RGS17,AGAP3,NTRK2,ARX,SNAP25,NMNAT2" MicroRNA hsa-miR-608:Functional MTI Functional MTI miRTarbase 7.79E-07 4.36E-03 1.12E-06 1.03E-05 23 195 "ARHGDIA,CRLF1,ZNF385A,IP6K1,SGSM2,ELN,MTSS1L,ANKFY1,GLI2,POLL,PRRC2B,KCNK3,MPP2,ZC3H12B,PKM,PLEC,PPARA,MAPK10,KLHDC8A,ATXN2,UNC5B,SEPT8,UBTF" MicroRNA hsa-miR-4662a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-07 4.41E-03 1.13E-06 1.04E-05 20 153 "TAOK1,C6orf89,VAT1L,ZBTB10,DST,OSBPL3,UBXN2A,MTX3,FEM1B,TRAF3IP2,CRCP,SLC2A6,OLA1,NCBP3,WDR37,SPART,ALG1,ZNF70,DHX33,MSRB3" MicroRNA hsa-miR-6801-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.09E-07 4.53E-03 1.16E-06 1.07E-05 17 114 "SLC24A4,TRMT9B,ARHGDIA,EPS15L1,TMEM184B,HAPLN1,TMEM170A,ANKFY1,HHIPL1,KPNA5,NLE1,SH3TC2,C12orf49,MYO18A,NUBPL,ZNF621,SGK3" MicroRNA hsa-miR-548ay-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-07 4.66E-03 1.19E-06 1.10E-05 15 90 "XKR4,SLC24A4,TNRC6C,ZNF385A,E2F6,AFF2,MIER3,IL6R,ITPKB,MAT2A,SAMD5,STRN3,ROBO1,FAM208A,CADM2" MicroRNA hsa-miR-28-3p:TargetScan hsa-miR-28-3p TargetScan 8.32E-07 4.66E-03 1.19E-06 1.10E-05 15 90 "RNF182,CACNA1G,FHL5,LETMD1,KIAA0408,MATR3,DTNA,FOXO3,LUZP2,MEIS1,GPR85,RAD51D,ATXN7,BHLHB9,GAN" MicroRNA hsa-miR-548at-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-07 4.66E-03 1.19E-06 1.10E-05 15 90 "XKR4,SLC24A4,TNRC6C,ZNF385A,E2F6,AFF2,MIER3,IL6R,ITPKB,MAT2A,SAMD5,STRN3,ROBO1,FAM208A,CADM2" MicroRNA hsa-miR-4495:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.37E-07 4.68E-03 1.20E-06 1.11E-05 18 127 "CCDC74A,ZBTB10,ATP2A2,FSD1L,EIF5,TUBD1,SCML2,MMADHC,SH3TC2,ALG9,PGBD4,FBXW7,BDP1,SYPL1,XPO1,FAM182B,PHTF2,NETO2" MicroRNA hsa-miR-3591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.82E-07 4.94E-03 1.27E-06 1.16E-05 13 68 "ARNTL,CALM1,ELMO1,CELF1,ZNF546,SMAD1,NCAM2,GPR137C,ZNF793,SALL1,SGK1,SOX11,CLASP1" MicroRNA hsa-miR-155-3p:Functional MTI Functional MTI miRTarbase 8.82E-07 4.94E-03 1.27E-06 1.16E-05 13 68 "ATP1A1,EPB41,ERBB2,MRVI1,IRAK3,SHC3,MYO6,NFIX,GTDC1,KIRREL1,FBXW7,SIRT1,TPM1" MicroRNA hsa-miR-6733-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.82E-07 4.94E-03 1.27E-06 1.16E-05 13 68 "FEM1B,GCK,MKLN1,OPRL1,SLC25A36,KIAA0895L,SLC2A5,CXXC4,ITPRID2,PRRC2C,SATB2,CCDC14,ZNF24" MicroRNA hsa-miR-4666b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.82E-07 4.94E-03 1.27E-06 1.16E-05 13 68 "TNRC6C,FOXN3,VCAN,PLXNA4,C8orf37,EIF1,TBC1D16,PDE3A,MGRN1,SSBP2,ZNF711,ZNF24,ZNF154" MicroRNA hsa-miR-106a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-07 4.94E-03 1.27E-06 1.17E-05 22 182 "TRMT9B,SCARB1,SPATA2,TIAM2,FKTN,CINP,GPR75,LILRA2,KAT7,MKLN1,PDE3A,PLIN1,PIGG,ZNF532,PTGR2,SALL1,CDK19,SSTR2,DICER1,GPR161,UBC,MFF" MicroRNA "TACGGGT,MIR-100:MSigDB" "TACGGGT,MIR-100:MSigDB" MSigDB 8.89E-07 4.97E-03 1.27E-06 1.17E-05 8 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,AP1AR,SLC44A1" MicroRNA "TACGGGT,MIR-99A:MSigDB" "TACGGGT,MIR-99A:MSigDB" MSigDB 8.89E-07 4.97E-03 1.27E-06 1.17E-05 8 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,AP1AR,SLC44A1" MicroRNA "TACGGGT,MIR-99B:MSigDB" "TACGGGT,MIR-99B:MSigDB" MSigDB 8.89E-07 4.97E-03 1.27E-06 1.17E-05 8 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,AP1AR,SLC44A1" MicroRNA hsa-miR-4268:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.90E-07 4.98E-03 1.28E-06 1.17E-05 14 79 "RNF157,TBC1D14,NDST3,CSNK1E,RUSC2,KIAA0319,AMOTL2,RAPGEF6,SRRM4,POLL,TRIM67,CBX5,CCDC14,UPF3A" MicroRNA hsa-miR-4486:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-07 5.16E-03 1.32E-06 1.22E-05 19 141 "SLC16A4,RIPOR2,ANKFY1,TRMO,UFM1,FUT9,MSANTD4,IRAK3,KCNN3,CHST6,PKM,PPP1R1A,BCAS3,ELP2,STUM,ARL10,PPIL6,UBC,ZNF154" MicroRNA hsa-miR-6132:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.41E-07 5.26E-03 1.35E-06 1.24E-05 18 128 "SEMA7A,CPNE5,LDLRAD4,FAM131B,DLC1,PDLIM5,CPLX1,CACFD1,MAP4,MSI1,PKD1,SALL1,HES6,PEX26,NFASC,CLASP1,GDPD5,HNRNPA3" MicroRNA hsa-miR-6836-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.41E-07 5.26E-03 1.35E-06 1.24E-05 18 128 "SEMA7A,CPNE5,LDLRAD4,FAM131B,DLC1,PDLIM5,CPLX1,CACFD1,MAP4,MSI1,PKD1,SALL1,HES6,PEX26,NFASC,CLASP1,GDPD5,HNRNPA3" MicroRNA hsa-miR-500b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.51E-07 5.32E-03 1.36E-06 1.25E-05 12 58 "MTUS1,ASGR1,ZBTB10,CCNT1,LONRF2,SPATA2,ZNF585B,HHIPL1,SLC35G1,KCNN3,RICTOR,LYPD6" MicroRNA hsa-miR-6715b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.63E-07 5.39E-03 1.38E-06 1.27E-05 15 91 "CPNE5,ZBTB10,YTHDC1,KLHL3,FEM1B,FCF1,TNRC6A,CIT,SLC35G1,MXI1,KSR2,PTPRN2,CSRNP3,TRA2B,ASXL3" MicroRNA hsa-miR-6777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.66E-07 5.40E-03 1.38E-06 1.27E-05 16 103 "OSBPL1A,ZNF578,VCAN,IP6K1,RCAN2,GABRG2,NFYA,SMIM11A,PKD1,SH3TC2,SPIN3,EXOC7,PLEKHH2,AGMO,SPIRE1,PPP1R3F" MicroRNA hsa-miR-329-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.66E-07 5.40E-03 1.38E-06 1.27E-05 16 103 "CA12,EPS15L1,TBC1D5,ERBB2,DOT1L,GNAL,ELOVL5,P2RY1,GLIPR1L2,PDPK1,CNNM2,CNTLN,PEX26,WRN,EMSY,SLC38A1" MicroRNA hsa-miR-509-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.66E-07 5.40E-03 1.38E-06 1.27E-05 16 103 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,BDP1" MicroRNA hsa-miR-217:Functional MTI Functional MTI miRTarbase 1.04E-06 5.84E-03 1.49E-06 1.37E-05 14 80 "INSYN2B,ZNF583,SRSF11,HINFP,OSBPL3,DNAL1,MTX3,FOXO3,TCERG1,BACH2,ROBO1,HSPA4L,SIRT1,FXR1" MicroRNA hsa-miR-3152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-06 5.84E-03 1.49E-06 1.37E-05 14 80 "MTA3,CYBB,KIAA0319,GOLGA7,FLYWCH1,NXPH3,DDX19B,SOWAHA,STX1B,PEX26,FAIM2,TROVE2,FAM124A,VLDLR" MicroRNA hsa-miR-627-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-06 5.88E-03 1.50E-06 1.38E-05 13 69 "OGT,PPP1R16B,ANKRD46,APH1A,RNF165,KANSL1,PTPRB,SHMT2,ST6GAL1,SEPHS1,KDM3A,CYB561A3,JMJD1C" MicroRNA hsa-miR-7-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-06 5.95E-03 1.52E-06 1.40E-05 22 184 "DGKI,DGKB,MYEF2,CPEB2,MAMLD1,EGFR,TUBGCP4,COPS8,PCLO,KCNB1,LIFR,LYPLAL1,OCRL,EPB41L4B,PPM1B,ZNF354C,KIAA1107,ARL10,EVI5,ADAMTS9,HNRNPA3,SPATA13" MicroRNA hsa-miR-1252-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-06 6.02E-03 1.54E-06 1.41E-05 20 156 "STX16,TOGARAM2,OSBPL3,E2F6,MRVI1,CELF1,TUBGCP4,COPS8,TNRC6A,CIT,TJAP1,LIFR,ZNF680,NPTX1,CLDN11,CCSER2,EPB41L4B,TRA2B,SOX11,TUBB2A" MicroRNA hsa-miR-583:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-06 6.02E-03 1.54E-06 1.41E-05 20 156 "CC2D2A,ZNF578,CCAR2,CALM1,AKAP6,ENTPD4,DBN1,CHRDL1,SARAF,PTPRT,NKD1,KITLG,GPR137C,PDZRN4,KIF27,CCDC88A,SPART,DIP2A,PUM2,CBX5" MicroRNA hsa-miR-3190-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-06 6.02E-03 1.54E-06 1.41E-05 20 156 "TAOK1,DPY19L3,LDHD,SRSF11,KIAA0040,FAM131B,C8orf37,CRCP,GPT2,GRIN2D,FICD,ZIC5,ZNF621,TRIM2,NSD1,ZNF106,SMUG1,BCL2L13,ZXDA,NETO2" MicroRNA hsa-miR-509-3-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-06 6.17E-03 1.57E-06 1.45E-05 16 104 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,BDP1" MicroRNA hsa-miR-6764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-06 6.32E-03 1.61E-06 1.48E-05 25 229 "NDRG3,PTCHD1,MTA3,MARCH4,TMEM184B,RTTN,RNF14,IP6K1,ELMSAN1,CNNM1,HEYL,EIF4G1,CELF1,NSG1,MSANTD4,CRCP,KIAA1958,BACH2,NKD1,IL6R,FAM216A,ZNF844,RGS12,ERCC6L2,TSPAN11" MicroRNA hsa-miR-1236-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-06 6.46E-03 1.65E-06 1.51E-05 12 59 "ARHGDIA,INSYN2B,IST1,RPS6KL1,SLC6A17,ZFYVE21,RBBP8,ZFP1,USP22,TUBB2A,UPF3A,TMEM63C" MicroRNA hsa-miR-2277-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-06 6.46E-03 1.65E-06 1.51E-05 12 59 "PRC1,TBPL1,CRY2,ING4,ANKMY1,CELF1,ATOH8,PKD1,PRKACB,CNNM2,MGRN1,UPF3A" MicroRNA hsa-miR-1307:mirSVR_lowEffct hsa-miR-1307:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-06 6.53E-03 1.66E-06 1.53E-05 22 185 "AMPD2,SUGT1P4-STRA6LP-CCDC180,CALB2,CABP1,CSNK1G3,RASSF2,TM9SF4,DCLK2,GNAO1,STON1,GPER1,GRIA2,RNFT2,AGBL5,NUCB2,SMIM7,NDUFS7,WBP1L,ADGRL3,TMPO,PIK3R5,SLC38A1" MicroRNA hsa-miR-4286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-06 6.57E-03 1.67E-06 1.54E-05 17 117 "TAOK1,ATP1A3,KSR1,CASTOR3,IP6K1,SEMA4D,ATP13A4,ANKFY1,ST6GALNAC3,SLC6A17,XRRA1,NFYA,CLIP1,SLC37A2,NSD1,RIMBP2,ZNF781" MicroRNA hsa-miR-4684-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-06 6.58E-03 1.67E-06 1.54E-05 29 292 "ADD1,PTCHD1,KIAA1324,TAOK1,MARCH4,MARK4,NUMB,CRY2,CTH,USP6NL,TMEM170A,MRO,AGBL5,SAMD5,PKIA,PTPRB,C12orf49,RORB,NCBP3,TRA2B,PEX26,TROVE2,FAM208A,ALG1,SLC44A1,TBC1D15,ZNF708,ZNF70,DHX33" MicroRNA hsa-miR-7-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-06 6.69E-03 1.70E-06 1.57E-05 21 171 "DGKI,DGKB,MYEF2,CPEB2,MAMLD1,TUBGCP4,COPS8,PCLO,KCNB1,LIFR,LYPLAL1,OCRL,EPB41L4B,PPM1B,ZNF354C,KIAA1107,ARL10,EVI5,ADAMTS9,HNRNPA3,SPATA13" MicroRNA hsa-miR-4736:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-06 6.69E-03 1.70E-06 1.57E-05 21 171 "CAMK2A,LONRF2,CFL2,LETMD1,PITPNM3,USP6NL,MRNIP,PTK2B,CELF1,FUT10,TNFAIP8L3,MATN3,SLC11A2,PDE3A,POLR2F,STUM,PEX26,MYH15,TMCC1,ZSCAN29,DPYSL5" MicroRNA hsa-miR-3622b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-06 6.69E-03 1.70E-06 1.57E-05 21 171 "SLC24A4,TXNDC16,ASPA,LDHD,CCNT1,RTTN,KRBA2,EGFR,ENPP6,ERBB2,MTHFD2,AGBL5,GPR137C,OLA1,KCTD15,TMEM145,FAM102A,KANK1,MGAT5B,ZNF70,ZNF189" MicroRNA hsa-miR-34a-3p:Functional MTI Functional MTI miRTarbase 1.22E-06 6.82E-03 1.73E-06 1.60E-05 14 81 "AXIN2,AK2,NCOR1,NCOR2,PPP1R16B,MTHFD2,LYVE1,MMP17,PDE4B,CPEB4,SIRT1,RPL7L1,ZNF711,URM1" MicroRNA hsa-miR-1203:mirSVR_highEffct hsa-miR-1203:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-06 6.82E-03 1.73E-06 1.60E-05 14 81 "KCNH8,CASKIN1,TAOK1,USP3,DMTF1,TNK2,NELFCD,GLI2,CLASRP,SEPT4,YY1AP1,ADHFE1,SYNE2,SPIRE1" MicroRNA hsa-miR-29b-3p:Functional MTI Functional MTI miRTarbase 1.24E-06 6.92E-03 1.76E-06 1.62E-05 27 261 "COL4A5,HDAC4,ELMSAN1,FEM1B,GOLGA7,RACK1,DOT1L,CIT,HMGCR,LAMA2,LIMS1,MYCN,ENPP2,PIK3R1,KCTD15,GTDC1,GLDN,S100B,SCAF8,SGK1,SEC31A,TET1,MAPKBP1,HECW1,RUNDC3B,TUBB2A,TMEM237" MicroRNA hsa-miR-376a-5p:Functional MTI Functional MTI miRTarbase 1.25E-06 6.98E-03 1.77E-06 1.63E-05 13 70 "CDK13,COPB2,SRSF11,CLTC,FCF1,NUCB2,ALG9,CHD9,SOX11,SYNE2,USP22,DICER1,SPATA13" MicroRNA hsa-miR-548ba:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-06 6.98E-03 1.77E-06 1.63E-05 13 70 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-9-3p:Functional MTI Functional MTI miRTarbase 1.26E-06 7.04E-03 1.79E-06 1.64E-05 16 105 "B4GALT6,C2CD2,KIAA0408,DMD,ATP13A4,SRCAP,ELOVL5,RBPJ,P2RX7,ABCB1,PPARA,MAPK3,TUG1,KLHL11,SLC25A36,HSPA4L" MicroRNA hsa-miR-139-5p:Functional MTI Functional MTI miRTarbase 1.26E-06 7.04E-03 1.79E-06 1.64E-05 16 105 "PDE4DIP,USP6NL,ARHGAP32,STAMBP,TNRC6A,KSR2,PDE4D,NCR3LG1,CHD9,SMARCA4,ADAMTS17,SYT5,TCF12,CFAP298,CIAPIN1,SPATA13" MicroRNA hsa-miR-3170:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-06 7.15E-03 1.81E-06 1.67E-05 19 144 "ADD1,C6orf89,BMP7,DIS3L,SOCS5,KIAA0586,PDLIM5,GLI2,TNRC6A,POLL,PRRC2B,ZNF491,GPR155,MAPK10,GDPD1,C12orf49,PTGR2,PUM2,ZNF24" MicroRNA hsa-miR-6855-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-06 7.15E-03 1.81E-06 1.67E-05 19 144 "ADD1,C6orf89,BMP7,DIS3L,SOCS5,KIAA0586,PDLIM5,GLI2,TNRC6A,POLL,PRRC2B,ZNF491,GPR155,MAPK10,GDPD1,C12orf49,PTGR2,PUM2,ZNF24" MicroRNA hsa-miR-3143:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-06 7.17E-03 1.82E-06 1.67E-05 15 93 "ADD1,AMPD3,BACH1,GAPVD1,MATR3,FAM13A,SPDL1,STX1B,SATB1,SHC4,FNDC3A,UBE2H,ZNF711,ZBTB38,EML6" MicroRNA hsa-miR-527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-06 7.38E-03 1.87E-06 1.72E-05 20 158 "GAS7,EPHB1,ACSL4,TNRC6A,PRRC2B,PRUNE2,MAPT,KITLG,KCTD15,PLEC,PEX26,ATF7IP,ATMIN,ZMAT3,NACC2,TUBB2A,ZBTB38,SLC30A4,ZXDA,HNRNPA3" MicroRNA hsa-miR-5589-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-06 7.42E-03 1.88E-06 1.73E-05 17 118 "CALM1,RASSF2,STARD3NL,ZBED3,TPPP,EID2B,IL6ST,KCNB1,HS6ST3,NPTX1,NCBP3,CPEB4,SIN3B,NACC2,ZNF138,MFF,PHTF2" MicroRNA hsa-miR-130a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-06 7.43E-03 1.88E-06 1.73E-05 18 131 "ZNF578,HAPLN1,DOCK4,TMEM170A,FSD1L,CELF1,MPP6,ADAM28,TNRC6A,ZNF426,ZIK1,ACSS3,SEMA6D,FNIP1,ERBIN,RPL7L1,ZNF138,JMJD1C" MicroRNA hsa-miR-3192-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-06 7.81E-03 1.98E-06 1.82E-05 12 60 "ADD2,CFL2,FOXN3,OSBPL3,RUSC2,MALT1,RAB30,POLL,L1CAM,REEP1,WNK3,FXR1" MicroRNA hsa-miR-2355-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-06 7.81E-03 1.98E-06 1.82E-05 12 60 "RNF157,CA12,UBXN2A,E2F6,CELF1,IL6ST,SHC3,SEPT4,CSRNP3,ZMAT3,NR2E1,VLDLR" MicroRNA hsa-miR-4445-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-06 7.88E-03 2.00E-06 1.84E-05 11 50 "GREB1,PUM1,RAB30,RASSF8,NCKAP1L,HECTD2,MBNL1,HS6ST3,ROBO1,ERC1,SATB2" MicroRNA hsa-miR-320b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-06 7.94E-03 2.01E-06 1.85E-05 19 145 "ADD1,SEMA7A,PHF12,TNRC6C,C2CD2,EPB41,SYNCRIP,SRCAP,GLUL,RBPJ,MKLN1,MAPK3,HSPA4L,ATF7IP,ERC1,TAL1,SATB2,ARL10,RNF103" MicroRNA hsa-miR-5588-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-06 8.01E-03 2.03E-06 1.87E-05 16 106 "NCKAP5,PTCHD1,SLC24A4,TXNDC16,SEMA7A,APAF1,SLC16A4,MTHFD2,BVES,KLHL23,NDUFS7,ALG9,STAC2,CYB561A3,VWCE,CBX5" MicroRNA hsa-miR-1915-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-06 8.03E-03 2.03E-06 1.87E-05 25 232 "NDRG3,PTCHD1,MTA3,MARCH4,TMEM184B,RTTN,RNF14,IP6K1,ELMSAN1,CNNM1,HEYL,EIF4G1,CELF1,NSG1,MSANTD4,CRCP,KIAA1958,BACH2,NKD1,IL6R,FAM216A,ZNF844,RGS12,ERCC6L2,TSPAN11" MicroRNA hsa-miR-17-3p:Functional MTI Functional MTI miRTarbase 1.45E-06 8.09E-03 2.05E-06 1.89E-05 21 173 "TXNDC16,SFMBT2,DNAH17,STX16,MYRF,P2RX6,IP6K1,OPTN,SRCAP,ATOH8,NACA,ENPP2,PKM,GPSM2,PLCD1,ELOVL2,TRIM68,ZNF423,HIRA,UBE2H,XPO1" MicroRNA hsa-miR-135a-5p:Functional MTI Functional MTI miRTarbase 1.47E-06 8.25E-03 2.09E-06 1.92E-05 15 94 "APC,CDR1,HEYL,EGFR,AMOTL2,KIAA1958,JAK2,MBNL1,PTK2,PTPRD,PEX2,PPM1E,ARC,SLC19A3,VLDLR" MicroRNA hsa-miR-218-2-3p:Functional MTI Functional MTI miRTarbase 1.48E-06 8.26E-03 2.09E-06 1.92E-05 13 71 "USP6NL,E2F5,DCTN4,RABEPK,STAMBP,OLA1,ZNF655,SETD5,ROBO1,ZNF415,ZC4H2,STAU1,ZNF195" MicroRNA hsa-miR-548ai:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-06 8.26E-03 2.09E-06 1.92E-05 13 71 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA "AGTCTTA,MIR-499:MSigDB" "AGTCTTA,MIR-499:MSigDB" MSigDB 1.48E-06 8.26E-03 2.09E-06 1.92E-05 13 71 "LRCH2,ZBTB10,PTBP2,CFL2,QKI,FAM131B,MYEF2,NOVA1,ENPP2,ZNF655,PPP3CA,RIC8B,SOX11" MicroRNA hsa-miR-23c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.31E-03 2.10E-06 1.93E-05 18 132 "ZNF578,HAPLN1,DOCK4,TMEM170A,FSD1L,CELF1,MPP6,ADAM28,TNRC6A,ZNF426,ZIK1,ACSS3,SEMA6D,FNIP1,ERBIN,RPL7L1,ZNF138,JMJD1C" MicroRNA hsa-miR-194-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.31E-03 2.10E-06 1.93E-05 18 132 "ARRB2,ARHGEF2,CSNK1E,IP6K1,SHISA6,LYPLAL1,SH3TC2,RAP1GDS1,ERI2,NCBP3,BTBD3,SNAP25,BDP1,BHLHB9,LAT2,EVI5,PRDM10,SPATA13" MicroRNA hsa-miR-3616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-06 8.36E-03 2.11E-06 1.94E-05 17 119 "DYNLL1,CLCN3,C3orf18,FKTN,FICD,MARK1,MYO5A,GPR137C,SLC25A23,FNDC3A,ANKRD6,CPEB4,DDN,TBCEL,ZNF106,KAT6B,ZKSCAN5" MicroRNA hsa-miR-214-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-06 8.56E-03 2.16E-06 1.99E-05 22 188 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,AKAP5,GREB1,DNAL1,YTHDC1,TOM1,TRAF3IP2,IGF1,KCNJ5,PEX2,NCBP3,SMARCC2,INAVA,UNC5B,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA "ACAACCT,MIR-453:MSigDB" "ACAACCT,MIR-453:MSigDB" MSigDB 1.54E-06 8.63E-03 2.18E-06 2.01E-05 10 41 "CDK10,CDK13,NCOA1,PCDH8,FBXW7,PKNOX2,BTBD7,MBD5,TAL1,LAS1L" MicroRNA hsa-miR-8062:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-06 9.10E-03 2.30E-06 2.11E-05 16 107 "MTA3,RTTN,FKTN,MSANTD4,FERMT2,RASSF8,EID2B,LYPLAL1,OCRL,NWD1,ROBO1,CSRNP3,SP2,AGTPBP1,SSBP2,RICTOR" MicroRNA hsa-miR-3174:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-06 9.10E-03 2.30E-06 2.11E-05 16 107 "CBR1,FOXN3,KIAA0040,MYADM,MTX3,ZFYVE21,PLEC,KANSL1,NKAIN1,SH3TC2,RBBP8,RDX,TRA2B,SLC6A8,THRA,TPM1" MicroRNA hsa-miR-924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-06 9.10E-03 2.30E-06 2.11E-05 16 107 "VXN,ISPD,TBRG4,RTTN,PPP1R16B,DBT,APH1A,SRCAP,PIK3R1,KANSL1,PTPRB,HSPA4L,SHMT2,ST6GAL1,SEPHS1,FAM126B" MicroRNA hsa-miR-620:Functional MTI Functional MTI miRTarbase 1.63E-06 9.10E-03 2.30E-06 2.11E-05 16 107 "TEX22,SLC24A4,PDE4DIP,UBXN2A,TMEM170A,SPATA2,FARSB,TUBD1,PRRC2B,BACH2,SHISA6,KLHL23,OLA1,SIK3,TUBB2A,ITM2C" MicroRNA hsa-miR-222-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-06 9.25E-03 2.33E-06 2.15E-05 14 83 "ADD1,COL4A5,ENTPD4,RGS17,ZNF585B,KITLG,GNG2,MTRF1L,CNTLN,RFX3,STAU1,RGMB,MKRN3,WNK2" MicroRNA hsa-miR-1268:mirSVR_highEffct hsa-miR-1268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.66E-06 9.28E-03 2.34E-06 2.15E-05 18 133 "UNC5A,CDK10,LETMD1,TRIM69,MYEF2,DDX46,TMCC2,SEMA3D,CGREF1,STMN2,FAM107A,KIT,LMO2,TMEM260,TCP11L1,FAM214B,NKAIN2,SEPT3" MicroRNA "TACAATC,MIR-508:MSigDB" "TACAATC,MIR-508:MSigDB" MSigDB 1.68E-06 9.40E-03 2.37E-06 2.18E-05 12 61 "NUMB,SEPT7,MSTN,GRIA2,GRM8,MITF,SATB1,ABLIM3,LMO3,CLASP1,RNF103,PHTF2" MicroRNA hsa-miR-195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-06 9.47E-03 2.38E-06 2.20E-05 15 95 "BID,CBS,CCNT1,CLCN3,CLTC,ABCG2,PREPL,UBE2E3,RBBP6,ERBIN,TUBB2A,CCDC14,TBC1D15,VSNL1,CADM2" MicroRNA hsa-miR-374c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-06 9.47E-03 2.38E-06 2.20E-05 15 95 "NRP2,HIPK3,TMTC1,FAM69A,MID1,SATB1,TRIM67,TROVE2,EXOC7,TRIM2,TRPS1,ZNF610,TBC1D15,SPIRE1,ZDHHC20" MicroRNA hsa-miR-3660:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-06 9.75E-03 2.45E-06 2.26E-05 13 72 "INTS2,CCNT1,PPP1R16B,RPS6KL1,AMOTL2,B4GALNT1,SESN1,LSAMP,CHIC1,GPSM2,PRKACB,TMEM200C,UPF3A" MicroRNA hsa-miR-5002-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-06 9.75E-03 2.45E-06 2.26E-05 13 72 "HECTD1,ZFP28,SUCO,TNRC6A,PRRC2B,NEGR1,SCIN,GPR155,MKLN1,MAPK10,NXT2,PCDHA6,SMARCAD1" MicroRNA hsa-miR-570-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-06 9.75E-03 2.45E-06 2.26E-05 13 72 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-339-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-06 1.02E-02 2.55E-06 2.35E-05 25 235 "SLC24A4,ZNF445,USP6NL,CENPL,TMEM170A,RCAN1,UFM1,BRSK1,GRIK4,SYNPO,MAP4,NOVA1,SLC11A2,KLHDC8A,NCBP3,TRA2B,AMBRA1,SLC11A1,SOX11,SULF2,FAM208A,SZT2,CBX5,ZNF708,FAM219B" MicroRNA hsa-miR-6761-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-06 1.03E-02 2.60E-06 2.39E-05 16 108 "KLHL32,ARHGDIA,TMEM184B,SLC43A2,MRVI1,SRRM4,SLC35G1,GPR173,PRKAB2,ATP8B4,CSRNP3,COPZ1,TMCC1,ASTN2,ZNF45,ZNF74" MicroRNA hsa-miR-6738-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-06 1.04E-02 2.61E-06 2.40E-05 18 134 "ARRB2,MTMR3,ARHGEF2,EVI5L,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,SEPT9,RNF165,MMP17,NFIX,HSD11B1L,SLC2A5,CAMTA2,SEPT8,RPL7L1" MicroRNA hsa-miR-4251:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-06 1.06E-02 2.66E-06 2.45E-05 17 121 "KLHL32,BACH1,KIAA0040,SLC43A2,MRVI1,AMOTL2,PRRC2B,LRRC75A,GPR173,KCTD15,PRKAB2,CSRNP3,ZNF621,TUBB2A,ZNF45,ZNF74,URM1" MicroRNA hsa-miR-6074:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-06 1.07E-02 2.70E-06 2.48E-05 14 84 "PTCH2,NUMB,EDN1,FCF1,YAF2,IL6ST,STMN1,PRKCB,BDP1,SS18,TBCEL,ZNF28,CADM2,SLC38A1" MicroRNA hsa-miR-6738-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-06 1.07E-02 2.70E-06 2.48E-05 14 84 "WDR35,DLGAP2,TOGARAM2,CPS1,BOC,DCAF8,TMEM170A,YTHDC1,EDN1,EPB41,PPM1L,RFX3,ASTN2,AGMO" MicroRNA hsa-miR-133b:Functional MTI Functional MTI miRTarbase 1.92E-06 1.07E-02 2.70E-06 2.48E-05 14 84 "CDK13,HCN2,PTBP2,ZFP28,HAPLN1,EGFR,FGFR1,ITPKB,KCNH2,PKM,ZMAT4,EMID1,SGK1,SIRT1" MicroRNA hsa-miR-218-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-06 1.10E-02 2.75E-06 2.54E-05 10 42 "PCDHGB4,CD38,IRAK4,FER,P2RX7,PIK3C2A,PIK3R1,ZNF426,RPL15,KLHL7" MicroRNA hsa-miR-561-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-06 1.13E-02 2.83E-06 2.60E-05 12 62 "BRAP,SLC24A4,SUMF2,IGDCC3,PLXNA4,FGFR1,SLC37A3,ITPKB,PTPRB,TMEM231,TAL1,NR2E1" MicroRNA hsa-miR-3181:mirSVR_highEffct hsa-miR-3181:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-06 1.13E-02 2.83E-06 2.60E-05 12 62 "UNC5A,SUGT1P4-STRA6LP-CCDC180,CDC14B,ARHGEF7,CPS1,PREPL,RASA4,FCGRT,EXOSC10,MASP1,PTPRE,FAM192A" MicroRNA hsa-miR-1273g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-06 1.13E-02 2.83E-06 2.60E-05 12 62 "BCL7A,CACNA1A,PTBP2,CD38,RUBCN,DOCK4,RAB30,XRRA1,NWD1,ZNF28,CIAPIN1,FXR1" MicroRNA hsa-miR-4526:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-06 1.15E-02 2.88E-06 2.65E-05 13 73 "INTS2,CCNT1,PPP1R16B,RPS6KL1,AMOTL2,B4GALNT1,SESN1,LSAMP,CHIC1,GPSM2,PRKACB,TMEM200C,UPF3A" MicroRNA hsa-miR-615-3p:mirSVR_highEffct hsa-miR-615-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.05E-06 1.15E-02 2.88E-06 2.65E-05 13 73 "SUGT1P4-STRA6LP-CCDC180,APOC1,BBS2,SCARB1,PTK2B,NELFCD,MAP7D2,CLASRP,RASSF8,PPARA,SEC14L1,RCOR3,CFAP298" MicroRNA hsa-miR-5194:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-06 1.16E-02 2.90E-06 2.67E-05 18 135 "ARRB2,MTMR3,ARHGEF2,EVI5L,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,SEPT9,RNF165,MMP17,NFIX,HSD11B1L,SLC2A5,CAMTA2,SEPT8,RPL7L1" MicroRNA hsa-miR-1238-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-06 1.16E-02 2.90E-06 2.67E-05 18 135 "TNRC6C,LDLRAD4,RUNX1T1,PLCXD3,DPYSL2,TMTC1,SLC43A2,SCML2,MAT2A,MBNL1,MID1,NFYA,ZNF844,ELP2,NLGN1,TFIP11,FAM13C,FRMD6" MicroRNA hsa-miR-6505-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-06 1.19E-02 2.99E-06 2.75E-05 11 52 "TMEM132B,ARNTL,CCPG1,HIPK3,INSYN1,KCTD6,THYN1,MYH15,LIMCH1,NECAB1,CBX5" MicroRNA hsa-miR-4777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-06 1.19E-02 2.99E-06 2.75E-05 11 52 "FOXN3,KIAA0408,FAM13A,MALT1,KIAA1958,LIMS1,POLR2F,ARMH4,WDR37,ITPRID2,EXOC7" MicroRNA hsa-miR-374b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-06 1.24E-02 3.11E-06 2.86E-05 15 97 "TAOK1,SOCS5,CPEB2,FEM1B,TNRC6A,MBNL1,MKLN1,PTPRD,ZC3H14,SALL1,ATXN2,ZC3H13,KANK1,ZMAT3,PRDM10" MicroRNA hsa-miR-886-3p:mirSVR_highEffct hsa-miR-886-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-06 1.24E-02 3.11E-06 2.86E-05 14 85 "TTLL9,LDB2,SH2B1,CCDC144A,DAPK1,CHST15,USP19,ZNF276,TJAP1,NLGN3,KCTD17,NUBPL,MPRIP,THRA" MicroRNA hsa-miR-4297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-06 1.24E-02 3.11E-06 2.86E-05 14 85 "THSD7A,NRG2,PITPNM3,SCRN1,IP6K1,TXNL4A,PTPRT,LSAMP,CHST6,NWD1,KIAA0895L,STUM,MGRN1,JMJD1C" MicroRNA hsa-miR-4319:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-06 1.24E-02 3.11E-06 2.86E-05 14 85 "LONRF2,ZNF385A,SMC2,CELF1,MUM1,NEGR1,SLC35G1,OPRL1,UBR7,COPZ1,ZNF177,DHX33,STOX2,TMEM63C" MicroRNA hsa-miR-6514-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-06 1.29E-02 3.22E-06 2.96E-05 21 178 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,AKAP5,GREB1,DNAL1,YTHDC1,TRAF3IP2,IGF1,KCNJ5,PEX2,NCBP3,SH3BP2,INAVA,UNC5B,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA hsa-miR-7856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-06 1.29E-02 3.22E-06 2.96E-05 18 136 "OSBPL6,TAOK1,ZBTB10,LDLRAD4,MYADM,LIN54,IP6K1,GORAB,COMMD5,PIK3R1,CEP97,RBBP6,GTDC1,EXD2,TMCC1,ITPRID2,SEPT3,FZD3" MicroRNA hsa-miR-6871-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-06 1.32E-02 3.31E-06 3.05E-05 16 110 "ELFN2,BACH1,NCOR2,SPATA2,SPECC1,KCNB1,NPTX2,GPR137C,SDK2,KANSL1,PTPRE,SETD5,KIAA0895L,PEX26,TPCN2,UBTF" MicroRNA hsa-miR-2682-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-06 1.32E-02 3.31E-06 3.05E-05 16 110 "SHROOM2,ZNF582,EVI5L,UBXN2A,EBI3,VTI1B,NEURL4,MALT1,FERMT2,ZNF546,MAP4,CNOT4,POLR2F,TROVE2,ZSCAN29,ZNF708" MicroRNA hsa-let-7a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-06 1.33E-02 3.33E-06 3.07E-05 17 123 "SPAG9,C1orf52,COPB2,ARMC8,CS,MYADM,SEMA4D,GABRG1,ZNF181,ZNF546,NCOA7,MBNL1,SETD4,CNKSR2,DIP2A,GPRIN3,SENP7" MicroRNA hsa-miR-568:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-06 1.35E-02 3.36E-06 3.09E-05 13 74 "ARRB1,ATP2A2,RUNX1T1,PUM1,EIF5,KATNAL1,MTHFD2,SRRM4,GCK,MIER3,JAK2,MPRIP,ACTR6" MicroRNA hsa-miR-4763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-06 1.35E-02 3.36E-06 3.09E-05 13 74 "TAOK1,USP37,ARHGDIA,ARSE,CFAP410,RNF14,IP6K1,VTI1B,CRCP,HSPA4L,SIN3B,GPRIN3,CFAP298" MicroRNA hsa-miR-499b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-06 1.35E-02 3.36E-06 3.09E-05 13 74 "HECW2,C2CD2,ABCC5,VPS13B,MRPL37,SESN1,PTPRT,FRMD5,SHISA6,KCTD6,FNDC3A,AGTPBP1,TFIP11" MicroRNA "GTATGAT,MIR-154:MSigDB" "GTATGAT,MIR-154:MSigDB" MSigDB 2.41E-06 1.35E-02 3.36E-06 3.09E-05 12 63 "PPP4R4,ZMYM4,TMEM184B,CNR1,GDA,ETV1,GALC,PDE4D,RBBP6,RFX3,PUM2,SIRT1" MicroRNA hsa-miR-154-5p:Non-Functional MTI Non-Functional MTI miRTarbase 2.41E-06 1.35E-02 3.36E-06 3.09E-05 12 63 "FZD9,DNAL1,E2F5,SESN1,CIT,ZNF678,SNRK,SLC25A36,ZFP30,DICER1,CLDND1,ZXDA" MicroRNA "GTATGAT,MIR-487:MSigDB" "GTATGAT,MIR-487:MSigDB" MSigDB 2.41E-06 1.35E-02 3.36E-06 3.09E-05 12 63 "PPP4R4,ZMYM4,TMEM184B,CNR1,GDA,ETV1,GALC,PDE4D,RBBP6,RFX3,PUM2,SIRT1" MicroRNA hsa-miR-362-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-06 1.35E-02 3.36E-06 3.09E-05 12 63 "MTUS1,ASGR1,ZBTB10,CCNT1,LONRF2,SPATA2,ZNF585B,HHIPL1,SLC35G1,KCNN3,RICTOR,LYPD6" MicroRNA hsa-miR-4724-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.47E-06 1.38E-02 3.45E-06 3.18E-05 10 43 "ADD1,EIF4G3,DCAF8,TM9SF4,DPYSL2,ZNF589,KCNN3,RXRA,ARHGAP9,HPS4" MicroRNA hsa-miR-6765-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-06 1.42E-02 3.53E-06 3.25E-05 15 98 "KLHL32,CEP126,LTBP4,CCNT1,C1orf52,RIMS4,PCYOX1,KAT7,ZNF491,IGF1,MSANTD2,SEPHS1,FAM208A,EVI5,URM1" MicroRNA hsa-miR-4301:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-06 1.43E-02 3.57E-06 3.29E-05 14 86 "OSBPL1A,PHF12,BACH1,CAMK2G,CELSR3,SEMA4D,POLL,NFYA,CNNM2,SH3TC2,SPIN3,KANSL3,DPYSL5,GAN" MicroRNA hsa-miR-5581-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-06 1.43E-02 3.57E-06 3.29E-05 14 86 "THSD7A,NRG2,PITPNM3,SCRN1,IP6K1,TXNL4A,PTPRT,LSAMP,CHST6,NWD1,KIAA0895L,STUM,MGRN1,JMJD1C" MicroRNA hsa-miR-891a:PITA hsa-miR-891a:PITA_TOP PITA 2.57E-06 1.44E-02 3.58E-06 3.30E-05 8 26 "XKR4,TAOK1,CNR1,DAPK1,MBNL2,SOX21,USP47,WDR47" MicroRNA hsa-miR-1180:mirSVR_highEffct hsa-miR-1180:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-06 1.47E-02 3.66E-06 3.37E-05 19 151 "PARG,TNRC6C,TTLL9,ARHGEF7,SCAPER,FRY,HPCAL4,AP4B1,MUM1,ZNF678,PCDH9,PCSK5,PPP2R5E,KANSL1,RASGRF2,BDP1,NUDT10,TPCN2,ST7" MicroRNA hsa-miR-365a-3p:Functional MTI Functional MTI miRTarbase 2.67E-06 1.49E-02 3.72E-06 3.42E-05 17 124 "PCDH10,AKAP12,CS,POLR1B,COMMD5,PAX6,PPP2R5E,KANSL1,SNRK,CYB561D1,PCMTD2,MCMBP,SGK1,ANKRD12,USP22,ZXDA,TRIM16L" MicroRNA hsa-miR-548an:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-06 1.49E-02 3.72E-06 3.42E-05 17 124 "ZNF582,CLCN3,HAPLN1,CDON,AMOTL2,GSN,KAT7,AFF1,P2RY1,PSAT1,NCR3LG1,CPEB3,SYPL1,SATB2,TOM1L2,CLDND1,EVI5" MicroRNA hsa-miR-1281:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-06 1.54E-02 3.83E-06 3.53E-05 21 180 "PLAA,IGLON5,ZBTB24,TUBD1,SLC43A2,FGFR1,PCYOX1,CRCP,ZNF655,FAM216A,STRN3,EXOSC10,APTX,ZSCAN2,ZNF844,NWD1,PRRT2,DIP2A,AGTPBP1,SSBP2,DPYSL5" MicroRNA hsa-miR-127-3p:TargetScan hsa-miR-127-3p TargetScan 2.80E-06 1.57E-02 3.90E-06 3.59E-05 7 19 "ATP2B2,RIMS4,MTSS1L,MAPK4,BCAS3,CYB561D1,LAS1L" MicroRNA "CGCTGCT,MIR-503:MSigDB" "CGCTGCT,MIR-503:MSigDB" MSigDB 2.80E-06 1.57E-02 3.90E-06 3.59E-05 7 19 "ACHE,PPFIA3,USP2,IP6K1,EIF4G1,ING4,ZNF423" MicroRNA hsa-miR-3177-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-06 1.57E-02 3.91E-06 3.60E-05 13 75 "TAOK1,DCAF8,TMEM130,DNAJB6,AFF2,GABRB3,KAT7,ZDHHC15,IL6ST,KIF13A,SP4,ARHGEF9,SATB2" MicroRNA hsa-miR-7844-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-06 1.57E-02 3.91E-06 3.60E-05 13 75 "OSBPL1A,EIF5,SEMA4D,SLC35G1,MEF2C,GPR137C,PDZRN4,PTPRG,PBRM1,CSRNP3,SOX11,ASXL3,ZIC2" MicroRNA hsa-miR-6879-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-06 1.59E-02 3.96E-06 3.64E-05 18 138 "XKR4,ATP1B3,NUMBL,TM9SF4,AMOTL2,SRCAP,PPM1L,NLE1,C1orf109,SH3TC2,ZMAT4,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,GAN" MicroRNA hsa-miR-2114-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.88E-06 1.61E-02 4.01E-06 3.69E-05 15 99 "PTCHD1,SLC24A4,TXNDC16,SEMA6A,APAF1,LDLRAD4,SLC16A4,CELSR3,ANKFY1,MTHFD2,SRCAP,BVES,KLHL23,CBX5,WBP2" MicroRNA hsa-miR-670-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.88E-06 1.61E-02 4.01E-06 3.69E-05 15 99 "SEMA4G,ZNF385A,RCAN1,EIF5,SEPT9,GRIK4,NEGR1,SLC35G1,KCTD15,DPF2,UBR7,GALNT10,TOM1L2,ZNF177,DHX33" MicroRNA hsa-miR-1274b:PITA hsa-miR-1274b:PITA_TOP PITA 3.14E-06 1.76E-02 4.37E-06 4.02E-05 20 167 "DOCK11,CNTNAP2,RIMS2,ANKFY1,GATM,BACH2,SMAP1,GPR62,NFIX,PRTG,PURG,RETREG2,CNNM2,PTPRD,FIGN,ZNF532,PPP4R3A,TBL1X,SLC44A1,TIAM1" MicroRNA hsa-miR-4525:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.20E-06 1.79E-02 4.45E-06 4.10E-05 19 153 "TAOK1,ARHGDIA,CAMK2A,METTL6,TMEM184B,PRRC2B,KCNH2,CHST6,MPP2,NFIX,PKM,DIRAS2,NCR3LG1,SARS,PKNOX2,FNBP1,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-4281:mirSVR_highEffct hsa-miR-4281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.28E-06 1.83E-02 4.55E-06 4.19E-05 15 100 "PKP4,SLC29A4,FCF1,NELFCD,AP4B1,TNRC6A,GPD2,ADAMTS13,ZFYVE21,RETREG2,MASP1,SCN8A,HECW1,MYCBP2,SEPT8" MicroRNA hsa-miR-653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.28E-06 1.84E-02 4.56E-06 4.20E-05 13 76 "AK2,BAG4,AASS,LUZP2,IL6R,SMAD9,PAX6,CLIP1,ANKRD6,SEPHS1,DOK6,TSN,UBC" MicroRNA hsa-miR-493-3p:TargetScan hsa-miR-493-3p TargetScan 3.33E-06 1.87E-02 4.63E-06 4.26E-05 17 126 "KIAA1211,FUBP1,P2RX6,QKI,EARS2,JAKMIP2,MRVI1,CPLX1,RAB30,NCKAP1L,PDE4D,GNG2,RORB,NFASC,ELP5,FAM219B,RSPRY1" MicroRNA hsa-miR-449c-5p:Functional MTI Functional MTI miRTarbase 3.39E-06 1.90E-02 4.71E-06 4.34E-05 16 113 "SHROOM2,ZNF582,EVI5L,UBXN2A,EBI3,VTI1B,NEURL4,MALT1,FERMT2,ZNF546,MAP4,CNOT4,POLR2F,TROVE2,ZSCAN29,ZNF708" MicroRNA hsa-miR-548ao-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.39E-06 1.90E-02 4.71E-06 4.34E-05 14 88 "JAZF1,CCNT1,BAG4,DBN1,MTX3,TAOK3,ZBED3,CRCP,MIER3,STMN1,PDE3A,OLA1,CSRNP3,HECW1" MicroRNA "GTTAAAG,MIR-302B:MSigDB" "GTTAAAG,MIR-302B:MSigDB" MSigDB 3.40E-06 1.90E-02 4.71E-06 4.34E-05 12 65 "ALCAM,ANK2,ARNTL,SYNJ1,NRXN3,CPEB2,ATP2C1,GAD1,PCDH9,ING3,ROBO2,ST8SIA2" MicroRNA hsa-miR-4318:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-06 1.90E-02 4.71E-06 4.34E-05 12 65 "BRAP,TRMT9B,LONRF2,PYGO1,AP4S1,RBPJ,LIMS1,MBNL1,MMP16,PEX2,ALG9,ELP2" MicroRNA hsa-miR-1288:PITA hsa-miR-1288:PITA_TOP PITA 3.40E-06 1.90E-02 4.71E-06 4.34E-05 12 65 "USP37,CAMK2G,CLCN3,OLFM1,FGF13,GPR137C,ZNF821,FBXO11,NMNAT2,ANKRD28,SZT2,KAT6A" MicroRNA hsa-miR-6769b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-06 1.93E-02 4.78E-06 4.40E-05 20 168 "TAOK1,BCL7A,PITPNM3,CELSR3,APH1A,GLI2,SOWAHA,METTL21A,MPP2,NFIX,GPR173,RETREG2,CEP97,ATXN2,UNC5B,SPART,CLASP1,RICTOR,ZNF708,ZNF28" MicroRNA hsa-miR-5010-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-06 1.97E-02 4.89E-06 4.50E-05 19 154 "TAOK1,ARHGDIA,CAMK2A,METTL6,TMEM184B,PRRC2B,KCNH2,CHST6,MPP2,NFIX,PKM,DIRAS2,NCR3LG1,SARS,PKNOX2,FNBP1,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-6848-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-06 2.08E-02 5.15E-06 4.74E-05 15 101 "BCL7A,CBARP,CS,ABCC5,MRNIP,TJAP1,PDE4A,SMOX,POLR2F,SARS,SBF1,STX1A,THRA,NACC2,WBP2" MicroRNA hsa-let-7e*:mirSVR_highEffct hsa-let-7e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-06 2.08E-02 5.15E-06 4.74E-05 15 101 "ADD1,MAGEE2,ZNF521,ARHGAP24,HS3ST2,AASDH,PLEKHA1,SYNCRIP,HNMT,CREG2,NF1,FERMT1,MAST1,FRYL,GAN" MicroRNA hsa-miR-595:Functional MTI Functional MTI miRTarbase 3.72E-06 2.08E-02 5.15E-06 4.74E-05 15 101 "ELFN2,PCDH10,MTMR3,CALM1,ENTPD4,KLHL3,PARD6A,ATP13A4,C15orf41,FICD,BLOC1S2,SLC25A23,PGBD4,MPRIP,TMPO" MicroRNA hsa-miR-6846-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-06 2.08E-02 5.15E-06 4.74E-05 15 101 "BCL7A,CBARP,CS,ABCC5,MRNIP,TJAP1,PDE4A,SMOX,POLR2F,SARS,SBF1,STX1A,THRA,NACC2,WBP2" MicroRNA hsa-miR-199a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.81E-06 2.13E-02 5.28E-06 4.86E-05 16 114 "QKI,COL4A5,LIN54,RGS17,ZNF585B,FLT1,FICD,ZHX1,IGF1,PKM,MTRF1L,MAPK9,ATF7IP,ZNF106,RGMB,WNK2" MicroRNA hsa-miR-4493:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.82E-06 2.14E-02 5.28E-06 4.87E-05 13 77 "TMCC3,ARHGDIA,AKAP5,IRAK3,PMP22,R3HDM2,MAPKBP1,SS18,SATB2,ZNF708,ZNF74,WNK2,NETO2" MicroRNA hsa-miR-5094:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.82E-06 2.14E-02 5.29E-06 4.87E-05 11 55 "ABCD2,MATR3,NEURL4,TNRC6A,LYPLAL1,PLCL1,ERI2,SLC25A36,PCMTD2,KIAA0895L,EVI5" MicroRNA hsa-miR-5011-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.82E-06 2.14E-02 5.29E-06 4.87E-05 11 55 "FOXN3,VCAN,PLXNA4,DNAL1,EIF1,CELF1,PDE3A,MPRIP,SSBP2,ZNF154,DHX33" MicroRNA hsa-miR-3129-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.82E-06 2.14E-02 5.29E-06 4.87E-05 11 55 "FZD9,JAZF1,NSL1,CLOCK,PYGO1,CHRDL1,EPDR1,RBBP6,PBRM1,GSTCD,SMARCAD1" MicroRNA hsa-miR-563:PITA hsa-miR-563:PITA_TOP PITA 3.85E-06 2.15E-02 5.32E-06 4.90E-05 10 45 "PTCHD1,KLHL13,FGF13,TCERG1,PBRM1,RTN1,TRIM2,UBE3A,MFF,WNK3" MicroRNA hsa-miR-1914-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-06 2.17E-02 5.36E-06 4.94E-05 18 141 "ARRB2,MTMR3,ARHGEF2,EVI5L,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,SEPT9,RNF165,MMP17,NFIX,HSD11B1L,SLC2A5,CAMTA2,SEPT8,RPL7L1" MicroRNA hsa-miR-2467-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.89E-06 2.18E-02 5.38E-06 4.96E-05 14 89 "SLC24A4,TAOK1,CEP126,ARHGDIA,CCNT1,CRY2,RIMS4,KIAA0408,TPPP,SETD5,C12orf49,DDN,ARC,URM1" MicroRNA hsa-miR-1249:mirSVR_highEffct hsa-miR-1249:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.02E-06 2.25E-02 5.55E-06 5.11E-05 12 66 "CDK10,RGN,KATNAL2,HRASLS5,CACFD1,ING3,SCN8A,SNCA,SULF2,ICAM5,PRDM8,PHTF2" MicroRNA hsa-miR-5187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-06 2.25E-02 5.55E-06 5.11E-05 12 66 "BACH1,CDC25B,SEC24C,DCAF8,DNAL1,SPATA2,ING4,GLUL,PRRC2B,NCR3LG1,STX1B,SARS" MicroRNA hsa-miR-7108-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-06 2.25E-02 5.55E-06 5.11E-05 12 66 "ELFN2,CARNS1,CFAP410,CRY2,SOCS5,ZNF678,MPP2,ALDH1L2,MRPS18A,ZNF331,DDN,TBCEL" MicroRNA hsa-miR-585:mirSVR_highEffct hsa-miR-585:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.02E-06 2.25E-02 5.55E-06 5.11E-05 12 66 "CDC25B,RUSC2,SNAP91,STAU2,TTBK1,MAT2A,MITF,CEP41,FBXO11,NUDT10,DNMBP,PUM2" MicroRNA hsa-miR-4462:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-06 2.34E-02 5.76E-06 5.31E-05 7 20 "PPFIA3,BAIAP3,OCRL,PKD1,LIMCH1,ERC1,MPRIP" MicroRNA hsa-miR-4649-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-06 2.36E-02 5.82E-06 5.36E-05 15 102 "SLC16A4,CBARP,ANKFY1,TRMO,FUT9,RNPS1,KCNN3,CHST6,PDE4A,ALG9,ATAT1,AP4E1,ARL10,PPIL6,UBC" MicroRNA hsa-miR-564:mirSVR_highEffct hsa-miR-564:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.28E-06 2.40E-02 5.91E-06 5.44E-05 16 115 "EP400,LGR5,PHC2,NOP56,CLASRP,STRN3,TMEM260,RIC8B,CAMTA1,CUX2,PCDHA2,SIK3,ZIC2,ZSCAN26,SLC17A7,TMEM63C" MicroRNA hsa-miR-338-3p:Functional MTI Functional MTI miRTarbase 4.29E-06 2.40E-02 5.92E-06 5.45E-05 18 142 "ZNF582,GPR146,ISPD,CDH2,FAM131B,TOM1,PLEKHA1,SCML2,SCARA3,MID1,NOVA1,PKM,ALG9,ATAT1,SALL1,PREX2,ZKSCAN3,CCDC14" MicroRNA hsa-miR-548ax:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.46E-06 2.49E-02 6.15E-06 5.66E-05 14 90 "JAZF1,CCNT1,BAG4,DBN1,MTX3,TAOK3,ZBED3,CRCP,MIER3,STMN1,PDE3A,OLA1,CSRNP3,HECW1" MicroRNA hsa-miR-4294:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-06 2.53E-02 6.24E-06 5.75E-05 20 171 "MTA3,SEMA7A,APAF1,ISPD,AKAP5,RNF14,DNAL1,CAMKK2,NFIX,ZNF426,STRN3,ELP2,SCN2B,HSPA4L,ZFP30,NUBPL,FAM126B,KIAA0930,ZNF106,ZNF708" MicroRNA hsa-miR-3145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-06 2.57E-02 6.34E-06 5.84E-05 11 56 "TAOK1,TRAF3IP2,ELOVL5,NEGR1,L1CAM,ZNF680,ATF7IP,SYP,PCDHA6,NDRG4,GAN" MicroRNA hsa-miR-5583-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-06 2.57E-02 6.34E-06 5.84E-05 11 56 "FZD9,JAZF1,NSL1,CLOCK,PYGO1,CHRDL1,EPDR1,RBBP6,PBRM1,GSTCD,SMARCAD1" MicroRNA hsa-miR-4762-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.62E-06 2.58E-02 6.36E-06 5.86E-05 17 129 "TMEM132B,INTS2,ZBTB10,CACNA1A,ZBED1,MITF,ENPP2,FAM98B,OLA1,PLCB2,PKIA,CNNM2,SCP2,BTBD3,FAM126B,PRDM10,JMJD1C" MicroRNA hsa-miR-1303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-06 2.59E-02 6.38E-06 5.88E-05 22 201 "TAOK1,IGDCC4,AKAP6,TBPL1,CPS1,HINFP,RUBCN,WDPCP,NEU3,ZNF276,IL6ST,LAYN,MYO5A,DEF8,ZNF793,FBXW7,ZFP30,FNDC3A,FHOD3,ATF7IP,ZNF708,MSRB3" MicroRNA hsa-miR-519e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-06 2.60E-02 6.39E-06 5.88E-05 21 186 "TNRC6C,ATP1B3,CACNA1A,NRG2,FAM131B,NR1D2,CELF1,GPD1,RABL2A,CELF5,IL6R,MYO5A,PRKAB2,CYB561D1,PCMTD2,ATXN7,SNAP25,ZNF621,SGK3,ZNF138,WNK2" MicroRNA hsa-miR-584-5p:Functional MTI Functional MTI miRTarbase 4.73E-06 2.65E-02 6.51E-06 5.99E-05 12 67 "USP6NL,TMEM170A,E2F5,DCTN4,STAMBP,FYN,OLA1,ZNF655,SETD5,ZNF415,CLDND1,ZNF195" MicroRNA hsa-miR-181b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-06 2.65E-02 6.51E-06 5.99E-05 12 67 "INSYN2B,SLC2A11,LONRF2,SRSF11,QKI,NSL1,ELMSAN1,GLUL,NFASC,SLC37A2,FAM124A,RPL7L1" MicroRNA hsa-miR-27b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-06 2.65E-02 6.51E-06 5.99E-05 12 67 "SLC24A4,TAOK1,TRMT9B,CDH2,SV2B,UFM1,SNX10,KIF27,TRA2B,FBXO11,TRPS1,PHTF2" MicroRNA hsa-miR-181b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-06 2.65E-02 6.51E-06 5.99E-05 12 67 "INSYN2B,SLC2A11,LONRF2,SRSF11,QKI,NSL1,ELMSAN1,GLUL,SLC37A2,TLR4,FAM124A,RPL7L1" MicroRNA hsa-miR-483-5p:Functional MTI Functional MTI miRTarbase 4.74E-06 2.65E-02 6.52E-06 6.01E-05 18 143 "TAOK1,ALCAM,TRMT9B,CBS,AKAP6,IGDCC3,HINFP,WDPCP,ZNF276,LAYN,NFIX,MAPK3,ZNF793,PRRT2,PEX26,TROVE2,ZNF708,ZNF70" MicroRNA hsa-miR-6885-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-06 2.65E-02 6.52E-06 6.01E-05 18 143 "AS3MT,ADCY6,PWWP2A,MTUS1,PCDH19,ARSE,NCOA1,PTBP2,LETMD1,KLHL5,NTNG2,NCAM2,NPTX1,ZSCAN2,ROBO1,SEPHS1,ANKRD28,UBE2H" MicroRNA hsa-miR-3920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-06 2.66E-02 6.54E-06 6.02E-05 10 46 "XKR4,FOXN3,PUM1,FOXF2,RAB30,POLL,KCNN3,DHX33,WNK3,DPF3" MicroRNA hsa-miR-6729-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.77E-06 2.67E-02 6.56E-06 6.04E-05 15 103 "SLC16A4,CBARP,ANKFY1,TRMO,FUT9,RNPS1,KCNN3,CHST6,PDE4A,ALG9,ATAT1,AP4E1,ARL10,PPIL6,UBC" MicroRNA hsa-miR-1234:PITA hsa-miR-1234:PITA_TOP PITA 4.79E-06 2.68E-02 6.58E-06 6.06E-05 8 28 "EVI5L,APH1A,LOXL3,MSI1,SCN8A,ZC3H4,SLC30A3,SEMA3B" MicroRNA hsa-miR-6088:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.95E-06 2.77E-02 6.80E-06 6.26E-05 20 172 "MTA3,CDC25B,DBT,JAKMIP2,PLEKHA1,GLUL,PRRC2B,KAT7,MIER3,CREG2,ZNF426,PPP2R5E,ELP2,SCN2B,FAM102A,NUBPL,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-4770:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.95E-06 2.77E-02 6.80E-06 6.26E-05 20 172 "MTA3,CDC25B,DBT,JAKMIP2,PLEKHA1,GLUL,PRRC2B,KAT7,MIER3,CREG2,ZNF426,PPP2R5E,ELP2,SCN2B,FAM102A,NUBPL,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-34b-3p:Functional MTI Functional MTI miRTarbase 5.02E-06 2.81E-02 6.90E-06 6.35E-05 22 202 "AS3MT,SFMBT2,ZNF583,CDR1,IPCEF1,DNAL1,SGSM2,MRNIP,GPR75,IL6R,SMAD9,MYCN,ABCB1,CEP97,CHD9,SEPHS1,SNCA,CDK19,NXT2,USP22,PCDHA6,ZBTB38" MicroRNA hsa-miR-4742-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.09E-06 2.85E-02 6.99E-06 6.44E-05 14 91 "EIF4G2,IGSF6,TMEM132C,FDFT1,C15orf41,ZIC5,RBPJ,GPR137C,PSAT1,SETD5,RMI1,TRPS1,TSN,RPL7L1" MicroRNA hsa-miR-1245b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.13E-06 2.87E-02 7.03E-06 6.48E-05 13 79 "ESYT2,C6orf89,FOXN3,MATR3,KCNN3,PDPK1,EPB41L4B,SARS,KIF21A,ZMAT3,RPL7L1,ZNF24,ZNF154" MicroRNA hsa-miR-3688-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.13E-06 2.87E-02 7.03E-06 6.48E-05 13 79 "PHF12,LDHD,SYNJ2,CFAP410,ENTPD4,CELF1,PARD3B,ZNF678,MYCN,RAP1GDS1,THRA,RGMB,TIGD6" MicroRNA hsa-miR-6734-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.13E-06 2.87E-02 7.04E-06 6.48E-05 17 130 "ELFN2,OGT,ARRB2,ARHGEF2,EVI5L,RPS6KL1,ABCC5,EIF1,SEPT9,GSN,RNF165,MMP17,PTPRE,SLC2A5,SEPT8,CBX5,RPL7L1" MicroRNA hsa-miR-302c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-06 2.93E-02 7.18E-06 6.61E-05 18 144 "INTS2,MAP4K4,VCAN,GAPVD1,MATR3,FAM13A,MTHFD2,TNRC6A,ZNF638,PLCL1,CEP97,SATB1,MYO18A,SHC4,FNDC3A,UBE2H,ZBTB38,EML6" MicroRNA hsa-miR-551b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-06 2.93E-02 7.18E-06 6.61E-05 18 144 "HFM1,ASPA,ZBTB10,ZMYM4,DGKB,MYEF2,MTX3,RGS17,C8orf37,ZNF391,LYVE1,MITF,PPM1B,FNDC3A,DIP2A,BHLHB9,ZNF711,EVI5" MicroRNA hsa-miR-1302:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-06 3.09E-02 7.56E-06 6.96E-05 11 57 "ARRB2,PPP1R16B,DNAL1,EIF5,METTL21A,STMN1,PKM,FBXW7,PEX26,SIGLEC10,GAN" MicroRNA hsa-miR-7974:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-06 3.11E-02 7.61E-06 7.00E-05 12 68 "SYNJ2,CACNA1A,C1orf52,NDST3,AKAP6,KIAA0040,ADAP1,KCNIP3,PEX26,FNBP1,PEG10,THRA" MicroRNA hsa-miR-6744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-06 3.11E-02 7.61E-06 7.00E-05 12 68 "GAS7,CDC25B,CPS1,PLXNA4,DNAL1,ING4,FAM120B,GPR137C,C1orf109,NKAIN1,FAM102A,NMNAT2" MicroRNA hsa-miR-5706:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-06 3.11E-02 7.61E-06 7.00E-05 12 68 "DPY19L3,MYRF,CLCN3,DCAF4,IL6ST,SEPT4,C1orf109,MYO18A,ZNF621,ZC3H4,NACC2,SLC30A4" MicroRNA hsa-miR-2861:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-06 3.11E-02 7.61E-06 7.00E-05 12 68 "APAF1,MYRF,NRG2,EGFR,MTSS1L,REEP2,NEU3,BCAS3,MRPS18A,SHMT2,ANKRD24,PARD3" MicroRNA hsa-miR-4782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-06 3.11E-02 7.61E-06 7.00E-05 12 68 "DPY19L3,MYRF,CLCN3,DCAF4,IL6ST,SEPT4,C1orf109,MYO18A,ZNF621,ZC3H4,NACC2,SLC30A4" MicroRNA hsa-miR-4672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.70E-06 3.19E-02 7.80E-06 7.18E-05 17 131 "ESYT2,BAG4,PITPNC1,SYT17,DIDO1,ZIC5,ZNF678,SFXN5,NEXMIF,PPP2R5E,CNNM2,ZNF532,C12orf49,ZNF415,NR2C2,UBTF,DHX33" MicroRNA hsa-miR-4766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.70E-06 3.19E-02 7.80E-06 7.18E-05 17 131 "SEMA7A,RTTN,AKAP12,RAB39B,KATNAL1,POLR1B,ZNF680,THYN1,CEP97,SH3TC2,ALG9,SLC8A1,ITPRID2,ZMAT3,RUNDC3B,PLEKHH2,CADM2" MicroRNA hsa-miR-627:PITA hsa-miR-627:PITA_TOP PITA 5.78E-06 3.23E-02 7.91E-06 7.28E-05 18 145 "MTMR3,RUNX1T1,AKAP7,NYAP1,GOLT1B,APH1A,RGS17,SRRM4,SOX21,ZC3H12B,NOVA1,KSR2,SEPT4,KANSL1,PPP4R3A,FAM214B,SOX11,RNF146" MicroRNA hsa-miR-4699-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-06 3.25E-02 7.94E-06 7.31E-05 14 92 "ABCD2,CSNK1G3,GOLT1B,HEYL,PRRC2B,ELOVL5,LOH12CR2,PTPRB,BTBD3,SLC8A1,SYT1,AGTPBP1,TRPS1,FXR1" MicroRNA hsa-miR-4330:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-06 3.25E-02 7.94E-06 7.31E-05 14 92 "ESYT2,INTS2,C1QTNF3,BCAS1,MATR3,CAMKK2,SESN1,IL6R,MBNL1,TBL1X,RPL7L1,ZNF24,ZXDA,RTN4" MicroRNA hsa-miR-3162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.85E-06 3.27E-02 7.99E-06 7.36E-05 10 47 "TAOK1,PHF12,MARK4,CACNA1G,CELSR3,GPD1,LSAMP,SDK2,ZNF793,ERCC6L2" MicroRNA hsa-miR-544b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.89E-06 3.30E-02 8.06E-06 7.42E-05 22 204 "ELFN2,RNF157,CCNT1,CDC25B,CPS1,SCML2,SIGLEC8,LUZP2,LILRA2,ZDHHC15,METTL21A,CHIC1,MMP17,SFR1,OPRL1,P2RX7,ATXN2,PEX26,NEK4,ZNF106,TUBB2A,RPL7L1" MicroRNA hsa-miR-5186:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-06 3.30E-02 8.06E-06 7.42E-05 25 251 "CBS,CDC25B,UBXN2A,GAPVD1,DNAL1,ATP13A4,TRMO,ZNF234,DISC1,KIAA1958,LILRA2,NKD1,IBA57,CHST6,BLOC1S2,CCSER2,CNNM2,MTMR10,RBBP8,CSRNP3,LHPP,PBLD,BHLHB9,PPIL6,TUBB2A" MicroRNA hsa-miR-3665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-06 3.30E-02 8.06E-06 7.42E-05 20 174 "CASKIN1,CAMK2A,USP6NL,PITPNC1,DPYSL2,ENPP6,PTK2B,FGFR1,SLC2A6,TNFAIP8L3,SHISA6,GPR155,MATN3,FXYD1,POLR2F,SEPHS1,MAPKBP1,GPRIN3,TPM2,DPYSL5" MicroRNA hsa-miR-515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.97E-06 3.34E-02 8.15E-06 7.51E-05 21 189 "TNRC6C,ATP1B3,CACNA1A,NRG2,FAM131B,NR1D2,CELF1,GPD1,RABL2A,CELF5,IL6R,MYO5A,PRKAB2,CYB561D1,PCMTD2,ATXN7,SNAP25,ZNF621,SGK3,ZNF138,WNK2" MicroRNA hsa-miR-545-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.01E-06 3.36E-02 8.20E-06 7.55E-05 16 118 "BAG4,LRIG1,ZIC5,ZNF678,FAM69A,MID1,ZNF426,CNTLN,SH3TC2,MCMBP,STX1B,PEG10,ITPRID2,SLC44A1,MKRN3,WNK3" MicroRNA hsa-miR-4285:mirSVR_highEffct hsa-miR-4285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.06E-06 3.39E-02 8.28E-06 7.62E-05 7 21 "RTL9,KCNAB3,SYT3,GLI2,SLC2A6,PTPRE,PPIL6" MicroRNA hsa-miR-941:mirSVR_highEffct hsa-miR-941:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.08E-06 3.40E-02 8.29E-06 7.63E-05 15 105 "TAOK1,CACNA1G,CLCN3,CNN3,CSNK1E,TNRC6A,VSIG4,MN1,SMIM11A,VPS13C,STK32A,ZFHX4,RGL1,CASC15,IFT88" MicroRNA hsa-miR-890:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.08E-06 3.40E-02 8.29E-06 7.63E-05 15 105 "AQP6,SLC16A4,FOXN3,UBXN2A,MYADM,TMTC1,ZNF391,ZNF585B,SMAD9,PRKCB,KLHDC8A,LIMCH1,MCF2L2,SLC19A3,HPS4" MicroRNA hsa-miR-33a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.37E-06 3.56E-02 8.69E-06 8.00E-05 18 146 "XKR4,C1QTNF3,CACNA1A,KIAA0408,MATR3,GUCD1,CPEB2,FYB1,MALT1,TNRC6A,GNAL,DIDO1,FIGN,RHBDL3,TCF12,ZMAT3,METTL3,RPL7L1" MicroRNA hsa-miR-4532:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.37E-06 3.56E-02 8.69E-06 8.00E-05 18 146 "RNF157,TXNDC16,LRFN1,CPNE5,CDC14B,KIAA0408,SGSM2,SLC43A2,FKTN,PDLIM5,CRCP,LIMS1,NWD1,RGS12,RXRA,ZFP30,TPCN2,ZNF106" MicroRNA hsa-miR-1306-5p:TargetScan hsa-miR-1306-5p TargetScan 6.38E-06 3.57E-02 8.70E-06 8.01E-05 22 205 "ABCF1,NDRG2,APC,BCL7A,DDR1,LDB2,CTH,KLHL3,RCAN1,EIF1,APC2,BTN2A1,MEIS1,PDE4A,PFKFB3,PLXNB1,PPP5C,PBRM1,ARL10,CBX5,RASD2,RGS7BP" MicroRNA "CACGTTT,MIR-302A:MSigDB" "CACGTTT,MIR-302A:MSigDB" MSigDB 6.40E-06 3.58E-02 8.73E-06 8.04E-05 8 29 "DOC2A,PUM1,FAM131B,NBEA,LRRC8A,SSBP2,DPYSL5,CPNE4" MicroRNA hsa-miR-1273h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.50E-06 3.64E-02 8.86E-06 8.16E-05 12 69 "ARHGDIA,COL9A1,CPS1,ABCC5,SLC43A2,GABRB3,RNF165,CYP27C1,AFF1,SLC25A36,VSNL1,GAN" MicroRNA hsa-miR-501-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.50E-06 3.64E-02 8.86E-06 8.16E-05 12 69 "CA12,MTHFD2,SESN1,AGBL5,IBA57,MSI1,PEG10,ZBTB43,SSTR1,PLCB1,UBE2H,FAM219B" MicroRNA hsa-miR-1178-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.50E-06 3.64E-02 8.86E-06 8.16E-05 12 69 "ABCF1,SFMBT2,CCPG1,PLXNA4,GPR155,MAPK9,RDX,HUNK,ANKRD36,ZMAT3,RPL7L1,PLSCR4" MicroRNA hsa-miR-370-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.58E-06 3.68E-02 8.96E-06 8.25E-05 11 58 "ABCF1,FOXN3,CRY2,ELMSAN1,MAP2,SMOX,RPS6KA2,KLHL4,CBX5,ZNF154,URM1" MicroRNA hsa-miR-647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.58E-06 3.68E-02 8.96E-06 8.25E-05 11 58 "ANK2,NCOA1,CACNA1A,C1orf52,SV2B,MRVI1,SRRM4,ADAP1,NFIX,ZNF426,ZNF610" MicroRNA hsa-miR-6797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.58E-06 3.68E-02 8.96E-06 8.25E-05 11 58 "ZNF445,FBXL5,STARD3NL,EIF1,NEURL4,TNRC6A,BACH2,PDE3A,SSBP2,KCNK12,WNK3" MicroRNA hsa-miR-6782-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.58E-06 3.68E-02 8.96E-06 8.25E-05 11 58 "MTX3,DPYSL2,CELSR3,TNRC6A,KCNN3,ADAM22,PFKFB3,UBR7,RXRA,SLC6A8,HPS4" MicroRNA hsa-miR-1275:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-06 3.81E-02 9.26E-06 8.52E-05 19 161 "TAOK1,ARHGDIA,CAMK2A,METTL6,TMEM184B,PRRC2B,KCNH2,CHST6,NFIX,PKM,DIRAS2,HSD11B1L,ZFP30,PKNOX2,FNBP1,NMNAT2,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-1204:mirSVR_highEffct hsa-miR-1204:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.82E-06 3.81E-02 9.27E-06 8.53E-05 13 81 "CFL2,TM9SF4,SEZ6L2,RACK1,CLASRP,FAM95B1,DNHD1,PDE3A,SLC25A23,PTPRG,ELMO2,EML6,UBE3B" MicroRNA hsa-miR-337-3p:Functional MTI Functional MTI miRTarbase 6.82E-06 3.81E-02 9.27E-06 8.53E-05 13 81 "MTA3,GAS7,RUNX1T1,CNN3,USP3,COQ7,ZDHHC15,IBA57,MARCH1,ZFP30,TRPS1,RICTOR,FXR1" MicroRNA hsa-miR-19b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "CD38,DMD,EDN1,CBX1,RASSF8,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-6810-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "TPP1,TBPL1,SEPT9,SRCAP,SESN1,TNRC6A,SCIN,MSI1,NBL1,PKM,POLR2F,COPZ1,UNC5B,CBX5,CIAPIN1" MicroRNA "ATCATGA,MIR-433:MSigDB" "ATCATGA,MIR-433:MSigDB" MSigDB 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "FOXN3,WDR20,ARRDC4,PHF20L1,PPARGC1A,PTPRT,JAK2,MARK3,MXI1,TTC13,KIF16B,SLA,EPN2,PDZRN3,ANKRD12" MicroRNA hsa-miR-6865-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "MARCH4,LRFN1,C6orf89,ZNF445,STOML1,AMOTL2,SMC2,ELOVL5,KCNN3,KIFC3,PFKFB3,STX1B,UHRF1BP1L,ZMAT3,SLC44A1" MicroRNA hsa-let-7g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "MAGED1,DLC1,FYN,GABRB3,KAT7,BACH2,KCNB1,NFIX,ZFYVE21,TRA2B,FNDC3A,PRRC2C,SLC44A1,ARL10,URM1" MicroRNA hsa-miR-1270:Functional MTI Functional MTI miRTarbase 6.84E-06 3.83E-02 9.29E-06 8.55E-05 15 106 "FZD9,TEX22,SLC24A4,PDE4DIP,UBXN2A,TMEM170A,FARSB,TUBD1,PRRC2B,BACH2,SHISA6,OLA1,SIK3,TUBB2A,ITM2C" MicroRNA hsa-miR-4632-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-06 3.92E-02 9.51E-06 8.75E-05 17 133 "XKR4,ATP1B3,NUMBL,TM9SF4,AMOTL2,SRCAP,PPM1L,C1orf109,SH3TC2,ZMAT4,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,GAN" MicroRNA hsa-miR-7843-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-06 3.92E-02 9.51E-06 8.75E-05 17 133 "XKR4,ATP1B3,NUMBL,TM9SF4,AMOTL2,SRCAP,PPM1L,C1orf109,SH3TC2,ZMAT4,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,GAN" MicroRNA hsa-miR-6769a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-06 4.17E-02 1.01E-05 9.30E-05 19 162 "TAOK1,BCL7A,PITPNM3,CELSR3,APH1A,GLI2,METTL21A,MPP2,NFIX,GPR173,RETREG2,CEP97,ATXN2,UNC5B,SPART,CLASP1,RICTOR,ZNF708,ZNF28" MicroRNA hsa-miR-4665-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-06 4.17E-02 1.01E-05 9.30E-05 19 162 "TAOK1,ARHGDIA,CAMK2A,METTL6,TMEM184B,PRRC2B,KCNH2,CHST6,NFIX,PKM,DIRAS2,HSD11B1L,ZFP30,PKNOX2,FNBP1,NMNAT2,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-1260a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-06 4.17E-02 1.01E-05 9.30E-05 19 162 "RNF150,MTA3,OSBPL1A,BACH1,CACNA1A,GAPVD1,RIPOR2,IP6K1,TNK2,MRPL37,MN1,PSAT1,CNNM2,GSTCD,SPIN3,STUM,KIF21A,KANSL3,GAN" MicroRNA hsa-miR-6748-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.48E-06 4.19E-02 1.02E-05 9.34E-05 16 120 "IGDCC4,BCL7A,CSNK1E,TNRC6A,TNFAIP8L3,MPP2,NFIX,RETREG2,CEP97,SETD5,CLIP1,UNC5B,TPCN2,UBTF,ZNF28,SLC38A1" MicroRNA hsa-miR-615-5p:Functional MTI Functional MTI miRTarbase 7.59E-06 4.25E-02 1.03E-05 9.47E-05 12 70 "ELFN2,CPNE5,IP6K1,FLYWCH1,COMMD5,NFIX,TBC1D25,ZNF426,HSD11B1L,ARC,AGTPBP1,THRA" MicroRNA hsa-miR-6771-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-06 4.35E-02 1.05E-05 9.71E-05 25 255 "KIAA1324,SEMA4G,DOCK11,PITPNM3,CTH,E2F6,MRO,ANKMY1,GLUL,KIAA1958,LUZP2,PRRC2B,CACFD1,AGBL5,IGF1,SAMD5,SLC11A2,PTPRB,C12orf49,RORB,IQSEC2,SYPL1,ALG1,ERCC6L2,TBC1D15" MicroRNA hsa-miR-3074-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "RALGAPA1,VXN,MYADM,MSANTD4,KCNMB4,LYPLAL1,AFF1,HSPA4L,NECAB1,ANKRD28,MTCH1" MicroRNA hsa-miR-6076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "ZNF445,FBXL5,STARD3NL,EIF1,NEURL4,TNRC6A,BACH2,PDE3A,SSBP2,KCNK12,WNK3" MicroRNA hsa-miR-488-5p:Functional MTI Functional MTI miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "SPATA2,RASGRP1,AFF2,IL6ST,KCTD15,ZNF426,PRKCB,NDUFS7,RXRA,CRB2,NELFE" MicroRNA hsa-miR-3937:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "LTBP4,ARHGDIA,TMEM184B,IGDCC3,ZNF385A,NCOR2,IRAK3,SEPT4,ZNF532,KCNIP3,CBX5" MicroRNA hsa-miR-6828-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "CACNA1A,DCAF8,HIPK3,COQ7,GSN,RFX3,ASTN2,GPRIN3,TPM1,VLDLR,ZBTB38" MicroRNA hsa-miR-26a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.83E-06 4.38E-02 1.06E-05 9.75E-05 11 59 "INTS2,CEP126,ZBTB10,FER,AFF2,GABRG2,SYT17,SHISA6,FAM192A,CSRNP3,HNRNPA3" MicroRNA hsa-miR-339-5p:PITA hsa-miR-339-5p:PITA_TOP PITA 7.83E-06 4.38E-02 1.06E-05 9.76E-05 13 82 "CCAR2,HAP1,EMX2,AGAP3,BRSK1,SRRM4,NNAT,NOVA1,TMEM260,USP47,THRA,UBE3A,TMEM237" MicroRNA hsa-miR-1288-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.43E-06 4.72E-02 1.14E-05 1.05E-04 9 39 "ESYT2,CREM,E2F6,FLYWCH1,RNF165,KCNH2,NFIX,KCTD15,WIPF1" MicroRNA hsa-miR-510-5p:Functional MTI Functional MTI miRTarbase 8.48E-06 4.75E-02 1.15E-05 1.06E-04 18 149 "SLC24A4,CDC14B,ZNF583,CBFA2T2,NRXN3,NCOR2,ELMSAN1,ZNF585B,GPR75,BVES,IBA57,KCNJ5,MAT2A,PPP2R5E,MTMR10,ELP2,SLC2A5,SPIRE1" MicroRNA hsa-miR-215:PITA hsa-miR-215:PITA_TOP PITA 8.51E-06 4.76E-02 1.15E-05 1.06E-04 14 95 "PCDH19,ALCAM,PKP4,DBT,CDON,KHDRBS3,SPIN1,LPAR4,PCDH9,NKAIN2,ADGRL3,DICER1,FAM155A,SMARCAD1" MicroRNA hsa-miR-4773:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-06 4.76E-02 1.15E-05 1.06E-04 14 95 "PHF12,SEC16A,FGF1,AFF2,CELF1,PTPRT,MORC4,SETD5,ALG9,FNIP1,TUBB2A,GORASP1,FXR1,RNF146" MicroRNA hsa-miR-192:PITA hsa-miR-192:PITA_TOP PITA 8.51E-06 4.76E-02 1.15E-05 1.06E-04 14 95 "PCDH19,ALCAM,PKP4,DBT,CDON,KHDRBS3,SPIN1,LPAR4,PCDH9,NKAIN2,ADGRL3,DICER1,FAM155A,SMARCAD1" MicroRNA hsa-miR-6735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.57E-06 4.80E-02 1.16E-05 1.07E-04 17 135 "XKR4,ATP1B3,NUMBL,TM9SF4,AMOTL2,SRCAP,PPM1L,C1orf109,SH3TC2,ZMAT4,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,GAN" MicroRNA hsa-miR-4683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.63E-06 4.83E-02 1.17E-05 1.07E-04 15 108 "SLC24A4,SMIM17,UBXN2A,FARSB,GLUL,PRRC2B,SHISA6,OLA1,HES6,SLC8A1,MYH15,SIK3,SSBP2,TUBB2A,GDPD5" MicroRNA "GTAAACC,MIR-299-5P:MSigDB" "GTAAACC,MIR-299-5P:MSigDB" MSigDB 8.68E-06 4.86E-02 1.17E-05 1.08E-04 10 49 "ABR,PHF12,CS,HDAC4,CPEB2,MAT2A,ROBO1,SGK1,PUM2,NAV3" MicroRNA hsa-miR-4693-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.68E-06 4.86E-02 1.17E-05 1.08E-04 10 49 "HEYL,AP4S1,RBPJ,LIMS1,MBNL1,MMP16,ALG9,ELP2,TMEM200C,CLASP1" MicroRNA hsa-miR-634:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "CSNK1E,ABCC5,PLEKHA1,F5,FGFR1,FAM107A,C2orf72,KCNN1,ZNF34,WBP2,ZNF154,DHX33" MicroRNA hsa-miR-4423-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "CLOCK,IP6K1,VTI1B,ZBED3,FERMT2,NCAM2,CNNM2,ATAT1,SLC8A1,OSBP2,WRN,CLDND1" MicroRNA hsa-miR-554:PITA hsa-miR-554:PITA_TOP PITA 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "LRFN1,QKI,YAF2,EIF1,TAOK3,HSF2,MITF,PIK3R1,KCTD15,TEX2,NXT2,TMEM237" MicroRNA hsa-miR-26a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "INTS2,CEP126,APAF1,ZBTB10,ACSL4,AFF2,GABRG2,SYT17,SHISA6,FAM192A,CSRNP3,HNRNPA3" MicroRNA hsa-miR-6512-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "TNRC6C,LDHD,ELMSAN1,SACS,ENPP6,KATNAL1,SAMD5,GPR137C,FIGN,TRPS1,ZNF711,ZNF189" MicroRNA "AAGGGAT,MIR-188:MSigDB" "AAGGGAT,MIR-188:MSigDB" MSigDB 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "CHRD,CDC25B,NBEA,MBNL1,MEF2C,KITLG,PCDH9,PDE4A,FBXW7,FBXO11,SLC12A2,RICTOR" MicroRNA hsa-miR-5590-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-06 4.94E-02 1.19E-05 1.10E-04 12 71 "CD38,PITPNM3,DBN1,EBF1,ZNF274,GDPD1,NWD1,SALL1,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-5087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.98E-06 5.02E-02 1.21E-05 1.11E-04 13 83 "CACNA1A,FEM1B,ENPP6,DLC1,SLC2A6,ALDH1L2,NCR3LG1,MARCH1,SEPHS1,TNS1,VSNL1,ZNF781,HNRNPA3" MicroRNA hsa-miR-371-3p:mirSVR_highEffct hsa-miR-371-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.98E-06 5.02E-02 1.21E-05 1.11E-04 13 83 "ARHGAP20,SGCE,CA4,CACNA1B,CDO1,TPK1,MALT1,IL6ST,CDK18,FAT4,SNX22,MCF2L,PDLIM2" MicroRNA hsa-miR-135b-5p:Functional MTI Functional MTI miRTarbase 8.98E-06 5.02E-02 1.21E-05 1.11E-04 13 83 "APC,CDR1,HEYL,AMOTL2,KIAA1958,MBNL1,MEF2C,MID1,PEX2,PPM1E,ARC,SLC19A3,EVI5" MicroRNA hsa-miR-6807-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.27E-06 5.19E-02 1.25E-05 1.15E-04 11 60 "INSYN2B,ZNF583,SRSF11,HINFP,OSBPL3,DNAL1,MTX3,TCERG1,BACH2,HSPA4L,FXR1" MicroRNA hsa-miR-6722-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.27E-06 5.19E-02 1.25E-05 1.15E-04 11 60 "ABCF1,MTA3,TTLL9,SYNJ2,MSANTD4,KDM2B,APTX,FAM102A,ATF7IP,MAP3K12,RNF170" MicroRNA hsa-miR-892a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.27E-06 5.19E-02 1.25E-05 1.15E-04 11 60 "KATNAL1,AP4S1,RBPJ,IL6ST,KLHL23,LIMS1,MBNL1,MMP16,ALG9,ELP2,TPM1" MicroRNA hsa-miR-663b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.27E-06 5.19E-02 1.25E-05 1.15E-04 11 60 "ELFN2,CARNS1,SOCS5,HRASLS5,MPP2,MRPS18A,BTBD3,DDN,SEPT8,ZC3H4,TBCEL" MicroRNA hsa-miR-892c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.64E-06 5.39E-02 1.30E-05 1.19E-04 14 96 "TAOK1,CDC25B,SEMA3D,LILRA2,SHISA6,KCNN1,KCNN3,STMN1,NPTX1,PCSK1,RFX3,ZNF189,SMARCAD1,SLC38A1" MicroRNA hsa-miR-19a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.68E-06 5.42E-02 1.30E-05 1.20E-04 15 109 "CD38,DMD,EDN1,CBX1,RASSF8,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-3607-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.74E-02 1.38E-05 1.27E-04 12 72 "ABCF1,FMNL2,TMEM184B,PLEKHA1,ZNF585B,MED12L,IL6ST,MCMBP,PLCB1,SIN3B,DICER1,ZNF24" MicroRNA hsa-miR-516b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.75E-02 1.38E-05 1.27E-04 13 84 "DPY19L3,MYRF,CLCN3,DCAF4,IL6ST,KLHL23,NFIX,C1orf109,NCBP3,MYO18A,ZC3H4,NACC2,CLDND1" MicroRNA hsa-miR-3928-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.76E-02 1.38E-05 1.28E-04 16 123 "ELFN2,STX16,RAB39B,SYNCRIP,PTPRT,MIER3,SHISA6,ZFYVE27,PDE3A,OXR1,KLHL11,DICER1,ZMAT3,RASD2,WRN,GAN" MicroRNA hsa-miR-302f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.78E-02 1.39E-05 1.28E-04 23 227 "ABCF1,APAF1,PTBP2,SUMF2,PLCXD3,DNAL1,SEMA3D,RASA4,ZNF585B,ZNF589,RBPJ,MXI1,PDE4D,ZNF844,ZDHHC14,ALG9,SNX22,MCF2L2,PRRC2C,ZMAT3,ZNF154,ZXDA,PARP11" MicroRNA hsa-miR-5681a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.85E-02 1.40E-05 1.29E-04 17 137 "PHF12,TUBD1,SEMA4D,FUT10,TJAP1,SCAMP5,MSANTD2,INAVA,POGZ,ZSCAN29,ZMAT3,RGMB,TUBB2A,UBC,MGAT5B,ZNF138,ITM2C" MicroRNA hsa-miR-4436b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.85E-02 1.40E-05 1.29E-04 17 137 "XKR4,ATP1B3,NUMBL,TM9SF4,AMOTL2,SRCAP,PPM1L,C1orf109,SH3TC2,ZMAT4,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,GAN" MicroRNA hsa-miR-200c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "FEM1B,TUBD1,SYNCRIP,C2orf72,EFHB,SLC11A2,POLR2F,PKIA,ZNF621,HPS4" MicroRNA "CTCTAGA,MIR-518F:MSigDB" "CTCTAGA,MIR-518F:MSigDB" MSigDB 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "ANK2,ADGRB3,CS,FHL1,TJAP1,ZC3H12B,ING3,SS18,KLHL7,PUM2" MicroRNA hsa-miR-6824-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "ELFN2,MTA3,METTL6,TMCC2,KCND1,OGG1,PKD1,HKR1,SETD5,ZNF423" MicroRNA "CTCTAGA,MIR-526A:MSigDB" "CTCTAGA,MIR-526A:MSigDB" MSigDB 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "ANK2,ADGRB3,CS,FHL1,TJAP1,ZC3H12B,ING3,SS18,KLHL7,PUM2" MicroRNA "CTCTAGA,MIR-526C:MSigDB" "CTCTAGA,MIR-526C:MSigDB" MSigDB 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "ANK2,ADGRB3,CS,FHL1,TJAP1,ZC3H12B,ING3,SS18,KLHL7,PUM2" MicroRNA hsa-miR-549a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.88E-02 1.41E-05 1.30E-04 10 50 "TAOK1,COPB2,IQGAP2,GLUL,KIT,NBPF1,MPRIP,TPCN2,RPL7L1,ZNF708" MicroRNA hsa-miR-558:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.88E-02 1.41E-05 1.30E-04 21 196 "ELFN2,ZNF578,TRMT9B,CCPG1,EPS15L1,AATK,UBXN2A,DNAL1,FAM13A,STX2,FGFR1,RNPS1,GSN,PLEC,CEP97,ALG9,FNIP1,HES6,PEX26,LHPP,USP1" MicroRNA hsa-miR-8089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-05 6.06E-02 1.45E-05 1.34E-04 15 110 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,KCNN3,WBP1L,C12orf49,UNC5B,SSTR1,LAT2" MicroRNA hsa-miR-4298:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-05 6.12E-02 1.47E-05 1.35E-04 11 61 "ARRB2,PPP1R16B,DNAL1,EIF5,METTL21A,STMN1,PKM,FBXW7,PEX26,SIGLEC10,GAN" MicroRNA hsa-miR-208b:PITA hsa-miR-208b:PITA_TOP PITA 1.10E-05 6.17E-02 1.48E-05 1.36E-04 8 31 "SYNJ1,IQCK,HDAC4,CPEB2,MIER3,RYR3,CHD9,ARHGEF9" MicroRNA hsa-miR-451a:Functional MTI Functional MTI miRTarbase 1.10E-05 6.17E-02 1.48E-05 1.36E-04 8 31 "IL6R,OXTR,ABCB1,PKD1,ZDHHC14,CUX2,TSC1,UBE2H" MicroRNA hsa-miR-208a:PITA hsa-miR-208a:PITA_TOP PITA 1.10E-05 6.17E-02 1.48E-05 1.36E-04 8 31 "SYNJ1,IQCK,HDAC4,CPEB2,MIER3,RYR3,CHD9,ARHGEF9" MicroRNA hsa-miR-656-3p:Functional MTI Functional MTI miRTarbase 1.14E-05 6.40E-02 1.53E-05 1.41E-04 16 124 "BRAP,KIAA0408,SPATA2,KATNAL1,SYNCRIP,FYB1,BACH2,L1CAM,PDPK1,CCSER2,PEX2,FBXW7,SIK3,NR2C2,ZNF138,ZXDA" MicroRNA hsa-miR-10b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-05 6.56E-02 1.57E-05 1.44E-04 13 85 "SEMA4G,ZBTB10,MATR3,EIF5,DNAJC27,SUCO,ZBTB49,NOVA2,PCSK1,SH3TC2,SALL1,SEMA6D,CLSTN2" MicroRNA hsa-miR-16-2-3p:Functional MTI Functional MTI miRTarbase 1.17E-05 6.56E-02 1.57E-05 1.44E-04 13 85 "BID,CBS,CCNT1,CLCN3,ABCG2,PREPL,UBE2E3,RBBP6,ERBIN,TUBB2A,CCDC14,TBC1D15,VSNL1" MicroRNA hsa-miR-6784-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-05 6.56E-02 1.57E-05 1.44E-04 13 85 "RUNX1T1,JAKMIP2,C3orf18,AMOTL2,CELF1,GABRB3,ELOVL5,TMOD2,C12orf49,HUNK,ZMAT3,ZNF781,ZNF195" MicroRNA hsa-miR-3119:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-05 6.56E-02 1.57E-05 1.44E-04 13 85 "CEP126,USP37,MARCH3,DST,THSD7A,ARHGAP32,AMOTL2,ZMAT1,NOVA2,NPTX1,BTBD3,RBM26,CLASP1" MicroRNA hsa-miR-4289:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-05 6.64E-02 1.59E-05 1.46E-04 12 73 "SEMA6A,MARCH4,LDHD,C8orf37,UBE2QL1,HLF,PAX6,SMIM7,SALL1,CPEB4,ZMAT3,ZNF106" MicroRNA hsa-miR-4725-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-05 6.64E-02 1.59E-05 1.46E-04 12 73 "CENPL,ANKMY1,TMEM164,SLC11A2,PDPK1,SH3TC2,PRRT2,KLHDC8A,COPZ1,SEPT3,ZC3H4,SZT2" MicroRNA hsa-miR-485-3p:Functional MTI Functional MTI miRTarbase 1.19E-05 6.64E-02 1.59E-05 1.46E-04 12 73 "DST,CLTC,RCAN2,NBEA,SRCAP,PPARGC1A,MKLN1,NTRK3,KANSL1,PBRM1,SS18,INTS3" MicroRNA hsa-miR-483-5p:PITA hsa-miR-483-5p:PITA_TOP PITA 1.20E-05 6.71E-02 1.60E-05 1.48E-04 7 23 "NDRG2,ALCAM,CPNE5,RNF165,NFIX,MAPK3,SOX11" MicroRNA hsa-miR-199b-5p:Functional MTI Functional MTI miRTarbase 1.21E-05 6.78E-02 1.62E-05 1.49E-04 15 111 "DDR1,ERBB2,GRB10,DDX19B,KIT,XRRA1,TMOD2,POLR2F,ZNF844,SLC8A1,ZFP1,SNAP25,ZNF415,SIRT1,ZNF195" MicroRNA hsa-miR-4432:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-05 6.87E-02 1.64E-05 1.51E-04 14 98 "TMEM170A,KATNAL1,TRMO,CELF1,CRCP,GPR75,SOWAHA,KNDC1,ZNF678,KPNA5,CHST6,ZNF844,TMEM9,TBC1D15" MicroRNA hsa-miR-29a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-05 6.87E-02 1.64E-05 1.51E-04 14 98 "FOXN3,HINFP,PUM1,HDAC9,RAB30,POLL,PTPRT,HLF,KCNN3,FAM98B,NWD1,DHX33,WNK3,DPF3" MicroRNA hsa-miR-8066:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-05 6.87E-02 1.64E-05 1.51E-04 14 98 "CA8,COPB2,UBXN2A,SV2B,MTX3,EIF5,PDE3A,USP47,UBR7,SLC25A36,SATB1,SYPL1,WBP2,TRPS1" MicroRNA hsa-miR-196b*:mirSVR_highEffct hsa-miR-196b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-05 6.87E-02 1.64E-05 1.51E-04 14 98 "FAHD2CP,UPRT,ERC2,NELFCD,FAM120B,PCDH17,COPS8,NRCAM,MAPK9,PTPRE,DZIP1,SOX3,C12orf76,XPO1" MicroRNA hsa-miR-1278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-05 7.07E-02 1.69E-05 1.55E-04 10 51 "RTTN,PYGO1,IST1,PLEKHA1,TMEM164,SARAF,RNPS1,BCAS3,SETD5,SEMA6D" MicroRNA hsa-miR-345-5p:Functional MTI Functional MTI miRTarbase 1.26E-05 7.07E-02 1.69E-05 1.55E-04 10 51 "CCPG1,E2F6,RNFT2,METTL21A,NTRK3,KCTD15,NWD1,ZNF667,ZNF106,CBX5" MicroRNA hsa-miR-138-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.27E-05 7.09E-02 1.69E-05 1.56E-04 16 125 "CCAR2,CDH2,IGLON5,BAG4,DNAJB6,FEM1B,CELF1,FERMT2,PPM1L,ZNF426,RELN,PTK2,RGS12,C12orf49,SIRT1,KCNK12" MicroRNA hsa-miR-2277:mirSVR_highEffct hsa-miR-2277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-05 7.09E-02 1.69E-05 1.56E-04 16 125 "ANK2,CFLAR,GREB1,DPP6,RCAN1,DNM1L,WDPCP,PAN3,IDNK,CDK5RAP2,MTCL1,FBXW11,SLC44A1,NPL,C9orf85,SNX14" MicroRNA hsa-miR-6891-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-05 7.10E-02 1.69E-05 1.56E-04 17 139 "XKR4,SORCS2,ZNF578,TRMT9B,CDC14B,LIN54,CHRDL1,MPP2,NBL1,NOVA2,TMEM231,ASTN2,NACC2,ASXL3,BCL2L13,WRN,ITM2C" MicroRNA hsa-miR-4714-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-05 7.47E-02 1.78E-05 1.64E-04 13 86 "SEC31B,UBXN2A,SV2B,MRNIP,ENPP6,FOXO3,CRCP,LRRC75A,MBNL1,GPR137C,PLCL1,BDP1,GAN" MicroRNA hsa-miR-6796-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.66E-02 1.82E-05 1.68E-04 12 74 "TRMT9B,AMPD3,TMEM184B,PYGO1,ELN,MAP4,PLEC,SLC25A23,SDK2,ATXN2,PEG10,NACC2" MicroRNA hsa-miR-6870-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.66E-02 1.82E-05 1.68E-04 12 74 "BEND6,EIF5,ANKMY1,PCDH17,ZNF638,TBC1D25,KANSL1,CNNM2,SH3TC2,ELOVL4,ZNF195,SIGLEC10" MicroRNA hsa-miR-198:Functional MTI Functional MTI miRTarbase 1.37E-05 7.66E-02 1.82E-05 1.68E-04 12 74 "PCDH19,LTBP4,CCNT1,FGFR1,PRRC2B,FUT10,DIDO1,MPP2,NNAT,NTRK3,ATF7IP,KIAA0930" MicroRNA hsa-miR-6812-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.66E-02 1.82E-05 1.68E-04 12 74 "ABCF1,AKAP5,CRY2,RNF14,FECH,TRAF3IP2,GPR75,KIAA1958,MTMR10,GPR161,ZNF34,ZNF74" MicroRNA hsa-miR-6878-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.68E-02 1.83E-05 1.68E-04 19 169 "ZNF578,CEP126,ZNF582,FOXN3,TNRC6A,ZNF638,GNAL,HAS2,C2orf72,PIK3C2A,ZNF426,C12orf49,ZNF568,HSPA4L,GPRIN3,ZNF34,CBX5,BCL2L13,ZNF70" MicroRNA hsa-miR-483-3p.1:TargetScan hsa-miR-483-3p.1 TargetScan 1.38E-05 7.74E-02 1.84E-05 1.69E-04 14 99 "MTMR3,GPC2,DBN1,RCAN2,AFF1,POLR2F,ROBO2,RPE,MYO18A,PEG10,IQSEC2,EXOC7,CDK20,HNRNPA3" MicroRNA hsa-miR-3611:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-05 7.74E-02 1.84E-05 1.69E-04 14 99 "CDC14B,CA8,SPAG9,CCNT1,CNGA3,NR1D2,GOLT1B,MRO,CELF1,PDE4D,SLC25A23,ALG9,SALL1,STOX2" MicroRNA hsa-let-7f-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-05 7.74E-02 1.84E-05 1.69E-04 14 99 "ZNF608,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,NCOA7,MBNL1,KIF13A,DIP2A,GPRIN3,USP1" MicroRNA hsa-miR-1289:Functional MTI Functional MTI miRTarbase 1.40E-05 7.85E-02 1.87E-05 1.72E-04 16 126 "TAOK1,AMH,SEMA7A,RGS6,DNAL1,CAMKK2,MPP2,ZNF426,ELP2,SCN2B,HSPA4L,NUBPL,FAM126B,KIAA0930,ZNF708,SLC30A3" MicroRNA hsa-miR-3675-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-05 8.21E-02 1.95E-05 1.80E-04 18 155 "FZD9,PTCHD1,KIAA1324,PDZD4,MARK4,CTH,SAMD5,TBC1D25,PTPRB,RORB,SNX22,SCN7A,DNAJC9,ALG1,CRTC1,SLC44A1,ZNF70,URM1" MicroRNA hsa-miR-5586-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-05 8.27E-02 1.96E-05 1.81E-04 20 185 "SLC24A4,KIAA1324,SOCS5,GREB1,TMEM170A,WDR20,RABEPK,ZNF549,TRAF3IP2,ZNF234,DDX19B,ZNF678,KCNN3,ZFYVE27,COMMD5,NUCB2,GPR137C,STK32A,NKAIN1,ZNF331" MicroRNA hsa-miR-19b-1-5p:Functional MTI Functional MTI miRTarbase 1.51E-05 8.43E-02 2.00E-05 1.84E-04 15 113 "CD38,DMD,EDN1,CBX1,RASSF8,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-6776-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-05 8.43E-02 2.00E-05 1.84E-04 11 63 "SLC24A4,QKI,KIAA0040,ANKRD46,HIPK3,TMTC1,SRCAP,SHISAL1,METTL21A,KCNB1,GPR155" MicroRNA hsa-miR-6853-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-05 8.43E-02 2.00E-05 1.84E-04 11 63 "BRAP,SORCS2,TAOK1,C1orf52,PLEKHA1,SAMD14,ZNF426,CCDC25,TROVE2,NR2E1,UBE3A" MicroRNA hsa-miR-7705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-05 8.47E-02 2.01E-05 1.85E-04 10 52 "SOCS5,KLHL3,INSYN1,CYP27C1,GPSM2,CEP97,NCBP3,KIF21A,KLHL7,ZMAT3" MicroRNA hsa-miR-6862-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-05 8.50E-02 2.02E-05 1.86E-04 13 87 "RUNX1T1,JAKMIP2,C3orf18,AMOTL2,CELF1,GABRB3,ELOVL5,TMOD2,C12orf49,HUNK,ZMAT3,ZNF781,ZNF195" MicroRNA hsa-miR-4531:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-05 8.58E-02 2.03E-05 1.87E-04 17 141 "TEX22,CCNT1,NSL1,SIPA1L1,PDE4DIP,UBXN2A,TMEM170A,DUSP9,PHC2,TUBD1,KIAA1958,BACH2,MAP2,GPR137C,SLC25A36,ZFAND5,ITM2C" MicroRNA hsa-miR-519d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-05 8.58E-02 2.03E-05 1.87E-04 17 141 "NCOA1,ATP1B3,CACNA1A,MYADM,RCAN1,GFER,IL6R,C2CD4C,MN1,MYO5A,TMOD2,KLHL11,CYB561D1,RORB,PCMTD2,ATXN7,SGK3" MicroRNA hsa-miR-7850-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-05 8.70E-02 2.06E-05 1.90E-04 14 100 "TEX22,OGT,UBXN2A,SRRM4,RNF165,ZIC5,KCNB1,MTRF1L,NKAIN1,GSTCD,MYO18A,FNDC3A,PARD3,PRDM10" MicroRNA hsa-miR-16-1-3p:Functional MTI Functional MTI miRTarbase 1.56E-05 8.70E-02 2.06E-05 1.90E-04 14 100 "FOXN3,CPS1,MATR3,GOLGA7,ACSL4,TRMO,KITLG,MKLN1,GNG2,ATF7IP,STAU1,CBX5,ZNF70,RNF146" MicroRNA hsa-miR-6834-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-05 8.70E-02 2.06E-05 1.90E-04 14 100 "ELFN2,OGT,ARHGEF2,ZNF385A,ABCC5,GSN,MMP17,NCR3LG1,MORC4,SLC2A5,SEPT8,CBX5,TPM2,TUBB2A" MicroRNA hsa-miR-4308:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-05 8.70E-02 2.06E-05 1.90E-04 14 100 "UBXN2A,IP6K1,ABCC5,EIF5,IRAK4,ANKMY1,CELF1,SEPT9,NCKAP1L,MTMR10,PEX26,DIP2A,EXOC7,KAT6A" MicroRNA hsa-miR-450a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-05 8.70E-02 2.06E-05 1.90E-04 14 100 "TPP1,SRCAP,GLI2,TNRC6A,PRRC2B,SCIN,MSI1,NBL1,MAPK10,COPZ1,NMNAT2,UNC5B,CBX5,CIAPIN1" MicroRNA hsa-miR-452-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.82E-02 2.09E-05 1.92E-04 12 75 "BEND6,HACE1,TXNDC16,BAG4,DPYSL2,HEYL,DOT1L,SEMA6D,TMCC1,ZNF621,TCF4,CLASP1" MicroRNA hsa-miR-571:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.82E-02 2.09E-05 1.92E-04 12 75 "MARCH4,CNTNAP2,PUM1,USP6NL,CELSR3,RABEPK,GLUL,FICD,NKAIN1,HSD11B1L,AMBRA1,TUBB2A" MicroRNA hsa-miR-3178:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.82E-02 2.09E-05 1.92E-04 12 75 "PTCHD1,TRMT9B,AMH,AQP6,NCOR2,CPLX1,BVES,IRAK3,FXYD1,ZNF426,ELP2,ZKSCAN3" MicroRNA hsa-miR-4720-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.82E-02 2.09E-05 1.92E-04 12 75 "DMTF1,AFF2,CELF1,TJAP1,IL6ST,MAP4,KLHL11,GLDN,COPZ1,TRIM67,ZMAT3,RASD2" MicroRNA hsa-miR-205-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-05 9.42E-02 2.23E-05 2.05E-04 17 142 "SORCS2,BCL7A,EXOG,RCAN2,IGSF6,KATNAL1,PDLIM5,SRRM4,TNRC6A,LUZP2,CREG2,CNNM2,BDNF-AS,ATF7IP,TET1,TROVE2,ZNF45" MicroRNA hsa-miR-193a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.71E-05 9.59E-02 2.27E-05 2.09E-04 16 128 "AK2,E2F6,SEMA3D,ASB3,COQ7,ERBB2,ERBB4,ANKFY1,KIAA1841,CACFD1,NF1,PTK2,MSANTD2,ELMO2,ZMAT3,RNF146" MicroRNA hsa-miR-550b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-05 9.59E-02 2.27E-05 2.09E-04 16 128 "CLK4,XKR4,PTBP2,CBS,DNAL1,ATP13A4,KNDC1,IBA57,CHST6,RAD51D,RBBP8,ATF7IP,SOX11,PPIL6,SSBP2,ZNF70" MicroRNA hsa-miR-1272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-05 9.64E-02 2.28E-05 2.10E-04 13 88 "ATP1B3,TOGARAM2,PPP1R16B,TUBA1B,MMADHC,KIAA1958,GPR137C,KANSL1,CNNM2,CSRNP3,ALG1,TCEA1,RTN4" MicroRNA hsa-miR-6801-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-05 9.64E-02 2.28E-05 2.10E-04 13 88 "XKR4,CLDN10,TOM1,MRO,RAB40B,MIER3,MAN2A2,NELL2,NFIX,OPRL1,SCN7A,NACC2,STOX2" MicroRNA hsa-miR-6810-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-05 9.64E-02 2.28E-05 2.10E-04 13 88 "XKR4,CLDN10,TOM1,MRO,RAB40B,MIER3,MAN2A2,NELL2,NFIX,OPRL1,SCN7A,NACC2,STOX2" MicroRNA hsa-miR-1206:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.76E-02 2.31E-05 2.12E-04 14 101 "SORCS2,TAOK1,CDC14B,TOGARAM2,RNF14,KIAA0408,PLEKHA1,C8orf37,CRCP,SAMD14,GPR137C,ZSCAN2,NR2E1,UBE3A" MicroRNA hsa-miR-4792:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.76E-02 2.31E-05 2.12E-04 14 101 "SYN3,PPP1R16B,DNAH9,FGFR1,ANKFY1,GPR75,POLL,SHISAL1,PLEC,C12orf49,EPN2,NACC2,ZNF70,GAN" MicroRNA hsa-miR-548u:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.76E-02 2.31E-05 2.12E-04 14 101 "ZNF608,TRMT9B,SFMBT2,LDHD,BAG4,CNTNAP2,KATNAL1,PACSIN2,ZNF678,AFF1,MN1,TCP11L1,TSC1,CLDND1" MicroRNA hsa-miR-7853-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.76E-02 2.31E-05 2.12E-04 14 101 "ZBTB10,NCOA1,ANKRD46,PLXNC1,RAB9B,COPS8,NPTX1,EPB41L4B,PEG10,TUBB2A,TOM1L2,ZNF225,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-431-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.80E-02 2.31E-05 2.13E-04 18 157 "ISPD,C1orf52,TBRG4,SOCS6,TBPL1,RTTN,DBT,EFCAB2,ZBED3,FYN,SIGLEC8,SRRM4,SRCAP,GPR155,HSPA4L,FAM126B,KLHL7,PCDHA6" MicroRNA hsa-miR-4708-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.85E-02 2.32E-05 2.14E-04 11 64 "INTS2,PUM1,MATR3,SCML2,RBPJ,PSD,SCN2B,CAMTA2,SATB2,CLASP1,NSD1" MicroRNA hsa-miR-8065:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.85E-02 2.32E-05 2.14E-04 11 64 "TAOK1,SPATA2,DLC1,AMOTL2,TJAP1,BLOC1S2,PKD1,ZSCAN2,SETD5,TUBB2A,ZNF781" MicroRNA hsa-miR-888-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.85E-02 2.32E-05 2.14E-04 11 64 "INTS2,KIAA0408,MTX3,ERBB2,AMOTL2,SESN1,RNPS1,FICD,PKD1,UPF3A,CADM2" MicroRNA hsa-miR-515-3p:Functional MTI Functional MTI miRTarbase 1.81E-05 1.01E-01 2.38E-05 2.19E-04 10 53 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,FLT1,PTPRT,AFF1,ADAM22,ZC3H12B" MicroRNA hsa-miR-4765:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-05 1.01E-01 2.38E-05 2.19E-04 10 53 "SEMA4G,ARHGDIA,IST1,RPS6KL1,SLC6A17,ZFYVE21,PMP22,RBBP8,TUBB2A,TMEM63C" MicroRNA "CTCCAAG,MIR-432:MSigDB" "CTCCAAG,MIR-432:MSigDB" MSigDB 1.81E-05 1.01E-01 2.39E-05 2.20E-04 12 76 "CAPN3,VXN,PITPNC1,CPEB2,STRADA,PDLIM5,GRIA2,PDE4A,PDE1B,PMP22,ANKRD28,TRIM9" MicroRNA hsa-miR-1279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-05 1.01E-01 2.39E-05 2.20E-04 12 76 "DBT,EDN1,ANKRD46,FRMD3,ZFYVE21,PURG,C12orf49,SYPL1,VLDLR,CLDND1,LYPD6,MFF" MicroRNA hsa-miR-3688-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-05 1.04E-01 2.46E-05 2.26E-04 15 115 "AK2,RUNX1T1,CDC25B,EGR3,TUBA1B,SYNCRIP,ZBED3,BVES,SAMD5,LRP12,HSPA4L,SLC6A8,ARL10,ZNF28,SLC38A1" MicroRNA hsa-miR-5047:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-05 1.09E-01 2.57E-05 2.37E-04 13 89 "SEMA6A,DST,CSNK1G3,YAF2,FAM13A,GLUL,KIAA1958,MBNL1,ZNF680,NBL1,CPEB3,WBP2,RUNDC3B" MicroRNA hsa-miR-1251:PITA hsa-miR-1251:PITA_TOP PITA 1.95E-05 1.09E-01 2.57E-05 2.37E-04 13 89 "FMNL2,APBB2,SLC25A14,VXN,CBARP,LHX2,MAML1,RNF165,HLF,IGF1,ENHO,TMEM237,NAV3" MicroRNA hsa-miR-877-5p:TargetScan hsa-miR-877-5p TargetScan 1.95E-05 1.09E-01 2.57E-05 2.37E-04 13 89 "BEND6,DPY19L3,CLTC,NCOR1,CSNK1G3,FSD1L,ANKFY1,CYP46A1,KAT7,FRMD3,PBRM1,NMNAT2,KIAA0930" MicroRNA hsa-miR-4285:mirSVR_lowEffct hsa-miR-4285:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-05 1.09E-01 2.57E-05 2.37E-04 14 102 "PTBP2,DAPK3,BAIAP2,DISC1,COPS8,NUCB2,CEP41,MRPS18A,RPL15,SMARCA4,ZC3H4,PDSS1,HIRA,ANKS1B" MicroRNA hsa-miR-3616-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-05 1.09E-01 2.57E-05 2.37E-04 14 102 "XKR4,ADCY5,OGT,NUMBL,CBARP,TM9SF4,E2F6,CHST15,SRCAP,PPM1L,SSTR1,PUM2,CBX5,GAN" MicroRNA hsa-miR-3158-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-05 1.09E-01 2.57E-05 2.37E-04 14 102 "ADD1,ESYT2,PHF12,NCOA1,STX16,APH1A,CHST15,ATOH8,PADI2,CYP27C1,ENPP2,UBE2H,VSNL1,WNK3" MicroRNA hsa-let-7a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-05 1.09E-01 2.57E-05 2.37E-04 14 102 "DLC1,FYN,GABRB3,KAT7,BACH2,KCNB1,NFIX,ZFYVE21,TRA2B,FNDC3A,PRRC2C,SLC44A1,ARL10,URM1" MicroRNA hsa-miR-657:Functional MTI Functional MTI miRTarbase 1.96E-05 1.09E-01 2.57E-05 2.37E-04 14 102 "TBPL1,PITPNC1,DPYSL2,ENPP6,CELF1,SLC2A6,GPR155,PEX26,SEPHS1,MAPKBP1,TMCC1,ZSCAN29,GPRIN3,EMSY" MicroRNA hsa-miR-133a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-05 1.10E-01 2.59E-05 2.39E-04 9 43 "CCAR2,BAG4,DNAJB6,FEM1B,EGFR,FERMT2,ZNF426,C12orf49,MPPE1" MicroRNA hsa-miR-572:PITA hsa-miR-572:PITA_TOP PITA 1.98E-05 1.11E-01 2.60E-05 2.40E-04 6 17 "PITPNM2,DGKG,PPARGC1A,NFIX,TMEM260,FAM155A" MicroRNA hsa-miR-1469:mirSVR_lowEffct hsa-miR-1469:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.02E-05 1.13E-01 2.66E-05 2.45E-04 17 144 "SUGT1P4-STRA6LP-CCDC180,CALB2,LYPD1,DTNB,DNM1L,TSPAN5,POLK,FUT10,GRIA2,SMAP1,NKAIN4,WDR25,MGRN1,TPCN2,TNS2,PIK3R5,TBC1D15" MicroRNA hsa-miR-221-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-05 1.13E-01 2.66E-05 2.45E-04 17 144 "SMIM17,ARHGDIA,DNAH17,MTMR3,CCNT1,UFM1,ZNF234,HAS2,IL6R,SEPT4,RPL15,SGSM1,KANSL3,FNBP1,UNC5B,PRRC2C,ZNF70" MicroRNA hsa-miR-6071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-05 1.15E-01 2.69E-05 2.48E-04 11 65 "DCAF8,SV2B,HIPK3,COQ7,FER,MYCN,RFX3,NCBP3,ASTN2,TPM1,ZBTB38" MicroRNA hsa-miR-514a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-05 1.15E-01 2.69E-05 2.48E-04 11 65 "IGDCC3,TUBD1,MSANTD4,BVES,KLHL23,NF1,BCAS3,NCBP3,R3HDM2,UHRF1BP1L,DIP2A" MicroRNA hsa-miR-4420:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-05 1.15E-01 2.69E-05 2.48E-04 11 65 "INSYN2B,SLC2A11,LONRF2,SRSF11,QKI,NSL1,ELMSAN1,GLUL,SLC37A2,FAM124A,RPL7L1" MicroRNA hsa-miR-3659:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-05 1.15E-01 2.69E-05 2.48E-04 11 65 "FOXN3,TMEM184B,LONRF1,IST1,KATNAL1,ATP13A4,PKM,PLEC,FAM126B,MGRN1,NSD1" MicroRNA hsa-miR-3938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-05 1.15E-01 2.69E-05 2.48E-04 11 65 "OSBPL1A,AK2,LDHD,MYRF,CCDC144A,CEP78,EID2B,ZNF793,SH3TC2,MYO18A,NETO1" MicroRNA hsa-miR-212-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.16E-01 2.73E-05 2.52E-04 18 159 "ZNF578,CACNA1A,CCNT1,DNAL1,RAB30,NFIX,PIK3C2A,ZNF426,C12orf49,ZNF568,STX1B,HSPA4L,TRIM67,POGZ,GPRIN3,ZNF34,NACC2,ZNF70" MicroRNA hsa-miR-552-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-05 1.17E-01 2.74E-05 2.52E-04 16 130 "INTS2,HACE1,CLOCK,VCAN,ELMSAN1,ANKRD46,KCNB1,LSAMP,MBNL1,XRRA1,NFYA,CCSER2,PLCL1,CEP97,SHC4,CUX2" MicroRNA hsa-miR-556-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-05 1.20E-01 2.81E-05 2.59E-04 10 54 "TRMT9B,SRSF11,UBXN2A,USP6NL,COPS8,ZIC5,MYCN,SETD5,NR2C2,CLDND1" MicroRNA hsa-miR-5004-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-05 1.20E-01 2.81E-05 2.59E-04 10 54 "GREB1,PUM1,SRRM4,HLF,C1orf109,NKAIN1,GSTCD,PGBD4,UHRF1BP1L,PARD3" MicroRNA hsa-miR-7160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-05 1.20E-01 2.81E-05 2.59E-04 10 54 "TXNDC16,LDLRAD4,APPL1,CYP46A1,CSDC2,CACFD1,NFIX,STX1A,ANKRD24,NETO2" MicroRNA hsa-miR-7161-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-05 1.22E-01 2.87E-05 2.64E-04 14 103 "ZNF608,TRMT9B,SFMBT2,LDHD,BAG4,CNTNAP2,KATNAL1,PACSIN2,ZNF678,AFF1,MN1,TCP11L1,TSC1,CLDND1" MicroRNA hsa-miR-4667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-05 1.22E-01 2.87E-05 2.64E-04 14 103 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,KCNN3,WBP1L,C12orf49,UNC5B,LAT2" MicroRNA hsa-miR-6780b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-05 1.23E-01 2.89E-05 2.66E-04 13 90 "AQP6,CACNA1A,SLC16A4,SOCS5,SPATA2,LILRA2,KLHL23,MEIS1,SH3TC2,MYO18A,ZBTB43,PRRC2C,ZDHHC20" MicroRNA hsa-miR-4425:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-05 1.23E-01 2.89E-05 2.66E-04 13 90 "XKR4,LDHD,DNAL1,TJAP1,PDE3A,MINDY2,FBXW7,FAM126B,STAU1,SULF2,NSD1,DPYSL5,GAN" MicroRNA hsa-miR-1204:PITA hsa-miR-1204:PITA_TOP PITA 2.21E-05 1.24E-01 2.89E-05 2.66E-04 7 25 "ASIC1,ADGRB1,CFL2,GRIN2D,MAP2,PDPK1,GTDC1" MicroRNA hsa-miR-4778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-05 1.26E-01 2.95E-05 2.71E-04 19 175 "RALGAPA1,FMNL2,SPOP,VXN,NUMBL,SOCS5,PLCXD3,TENM1,RABEPK,DLC1,GABRG2,SHISA6,SRSF12,NPTX2,PLCL1,POLG,PRKCB,AP1AR,BDP1" MicroRNA hsa-miR-5691:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-05 1.28E-01 3.01E-05 2.77E-04 16 131 "AS3MT,ISPD,TBRG4,DBT,ZC3H11A,GOLGA7,GSN,GPR155,MKLN1,SEPT4,HSPA4L,KLHL7,ADAMTS17,ZNF74,LYPD6,ZNF154" MicroRNA hsa-miR-449b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-05 1.28E-01 3.01E-05 2.77E-04 15 117 "CRY2,OSBPL3,HEPH,ANKMY1,SPECC1,SRRM4,GPER1,MSL1,IL6ST,KANSL1,PTCH1,WDR37,SYT5,CBX5,UBE2H" MicroRNA hsa-miR-4654:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-05 1.33E-01 3.10E-05 2.86E-04 12 78 "LONRF2,NRG2,SEC24C,DCAF8,E2F6,GLUL,NEGR1,METTL21A,PMP22,CAMTA2,CLASP1,WNK2" MicroRNA hsa-miR-3145-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-05 1.33E-01 3.10E-05 2.86E-04 12 78 "CBS,C2CD2L,FSD1L,CRCP,BACH2,KCNB1,NPTX1,PAX6,TMOD2,CCSER2,FNBP1,AGMO" MicroRNA hsa-miR-6511a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-05 1.33E-01 3.10E-05 2.86E-04 12 78 "RUNX1T1,JAKMIP2,RCAN2,CELF1,MPP6,GGT7,ADAMTS13,C12orf49,SNX22,HUNK,ZNF781,ZNF195" MicroRNA hsa-miR-4704-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-05 1.33E-01 3.11E-05 2.86E-04 11 66 "AK2,BAG4,TPK1,PKD1,GPSM2,PNMA3,PTPRE,NCBP3,USP22,DHX33,FXR1" MicroRNA hsa-miR-3622a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-05 1.33E-01 3.11E-05 2.86E-04 11 66 "APAF1,CLOCK,ZBED3,TXNL4A,NCAM2,TMEM104,ATAT1,SLC8A1,SS18,RPL7L1,WRN" MicroRNA hsa-miR-3152-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-05 1.33E-01 3.11E-05 2.86E-04 11 66 "PPP1R16B,DNAJB6,TRAF3IP2,CRCP,FICD,ZNF678,KCNN3,LAMP2,MAPK10,SETD5,ASTN2" MicroRNA hsa-miR-5088-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-05 1.33E-01 3.11E-05 2.86E-04 11 66 "MARCH4,CPNE5,ARHGDIA,CABP7,SEC16A,AMOTL2,SEMA4D,NEGR1,KPNA5,NLGN1,NFASC" MicroRNA hsa-miR-517c:PITA hsa-miR-517c:PITA_TOP PITA 2.40E-05 1.34E-01 3.13E-05 2.88E-04 9 44 "EIF4G3,CACNA1A,ZNF521,DBN1,LYPD1,PTK2B,TMCC1,USP1,MPPE1" MicroRNA "TAGGTCA,MIR-192:MSigDB" "TAGGTCA,MIR-192:MSigDB" MSigDB 2.40E-05 1.34E-01 3.13E-05 2.88E-04 9 44 "PCDH19,ALCAM,PKP4,LRRFIP1,DBT,LPAR4,LARP4,ADGRL3,RICTOR" MicroRNA hsa-miR-517a:PITA hsa-miR-517a:PITA_TOP PITA 2.40E-05 1.34E-01 3.13E-05 2.88E-04 9 44 "EIF4G3,CACNA1A,ZNF521,DBN1,LYPD1,PTK2B,TMCC1,USP1,MPPE1" MicroRNA "TAGGTCA,MIR-215:MSigDB" "TAGGTCA,MIR-215:MSigDB" MSigDB 2.40E-05 1.34E-01 3.13E-05 2.88E-04 9 44 "PCDH19,ALCAM,PKP4,LRRFIP1,DBT,LPAR4,LARP4,ADGRL3,RICTOR" MicroRNA hsa-miR-708-5p:Functional MTI Functional MTI miRTarbase 2.45E-05 1.37E-01 3.19E-05 2.94E-04 14 104 "CNTFR,PCYOX1,AHDC1,PRRC2B,RNF165,KCNH2,NNAT,NRCAM,KLHL11,SEC14L1,MYH15,IQSEC2,THRA,TUBB2A" MicroRNA hsa-miR-6827-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-05 1.37E-01 3.19E-05 2.94E-04 14 104 "ELFN2,HCN2,TMEM184B,E2F6,MTSS1L,ANKFY1,TNFAIP8L3,NEGR1,NPTX2,PKD1,RPS6KA2,PEAR1,CAMTA2,RPRM" MicroRNA hsa-miR-920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-05 1.39E-01 3.24E-05 2.99E-04 13 91 "ELFN2,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,ERC1,NFASC,CAMTA2,APOM,PPIL6,RPRM" MicroRNA hsa-miR-6726-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-05 1.39E-01 3.24E-05 2.99E-04 13 91 "ELFN2,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,ERC1,NFASC,CAMTA2,APOM,PPIL6,RPRM" MicroRNA hsa-miR-5591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-05 1.39E-01 3.24E-05 2.99E-04 13 91 "ELFN2,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,ERC1,NFASC,CAMTA2,APOM,PPIL6,RPRM" MicroRNA hsa-miR-1273c:mirSVR_highEffct hsa-miR-1273c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-05 1.41E-01 3.29E-05 3.03E-04 16 132 "DPY19L2P4,RTL9,OGT,BLM,NUMBL,CACNA2D2,SEMA3D,EGFR,RBPJ,RFX2,STK32B,MEG3,SMPD3,SMARCA4,TCEAL7,RGS7BP" MicroRNA hsa-miR-6805-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-05 1.41E-01 3.29E-05 3.03E-04 16 132 "AS3MT,ISPD,TBRG4,DBT,ZC3H11A,GOLGA7,GSN,GPR155,MKLN1,SEPT4,HSPA4L,KLHL7,ADAMTS17,ZNF74,LYPD6,ZNF154" MicroRNA hsa-miR-3680-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-05 1.42E-01 3.30E-05 3.04E-04 10 55 "ZNF578,ZNF589,MPP6,ELOVL5,USP51,SHISA6,SYTL4,TMOD2,USP22,AGMO" MicroRNA hsa-miR-7112-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-05 1.42E-01 3.30E-05 3.04E-04 10 55 "ELFN2,EVI5L,PUM1,CPLX1,TPPP,C2orf72,MN1,ZNF713,SP2,BCL2L13" MicroRNA hsa-miR-184:Functional MTI Functional MTI miRTarbase 2.54E-05 1.42E-01 3.30E-05 3.04E-04 10 55 "ARHGDIA,TPP1,CSF1,TM9SF4,LIFR,PKM,PRKCB,ZFPM2,LRRC8A,KLC2" MicroRNA "GTACAGG,MIR-486:MSigDB" "GTACAGG,MIR-486:MSigDB" MSigDB 2.54E-05 1.42E-01 3.30E-05 3.04E-04 10 55 "DYNLL1,ARMC8,FGF13,GABRB3,MARK1,PIK3R1,RBBP6,PDZRN3,ST5,PUM2" MicroRNA hsa-miR-183-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-05 1.42E-01 3.31E-05 3.05E-04 15 118 "OSBPL8,PROM1,CLCN3,CHST15,NEGR1,IBA57,LAMA2,N6AMT1,SH3TC2,BDP1,FNBP1,KCNT2,ZNF138,TFIP11,ADAMTS9" MicroRNA hsa-miR-3193:mirSVR_highEffct hsa-miR-3193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-05 1.48E-01 3.45E-05 3.17E-04 17 147 "KCNAB2,SEMA4G,BID,CBR1,SNCAIP,CSF2RA,ARHGAP24,DDX46,PAN3,ADAMTS6,SMAP1,TBC1D25,ABCA11P,CDK5RAP2,KDM4B,PEG10,AKTIP" MicroRNA hsa-miR-3129-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-05 1.51E-01 3.52E-05 3.24E-04 12 79 "QKI,COL4A5,LIN54,RGS17,ZNF585B,FICD,PKM,MTRF1L,ATF7IP,ZNF106,RGMB,WNK2" MicroRNA hsa-miR-6511b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-05 1.51E-01 3.52E-05 3.24E-04 12 79 "RUNX1T1,JAKMIP2,RCAN2,CELF1,MPP6,GGT7,ADAMTS13,C12orf49,SNX22,HUNK,ZNF781,ZNF195" MicroRNA hsa-miR-744:mirSVR_highEffct hsa-miR-744:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-05 1.53E-01 3.55E-05 3.27E-04 14 105 "PTCHD1,BIN1,STK33,CD86,EDNRA,PHC2,ELN,FCGRT,RNF165,NBL1,CDK18,NALCN,RGS3,IQSEC2" MicroRNA hsa-miR-486-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-05 1.54E-01 3.58E-05 3.30E-04 11 67 "MARCH4,NRP2,CLDN10,DCTN4,CIT,ZIC5,PIK3R1,RCOR3,SP4,CCDC14,ZDHHC20" MicroRNA hsa-miR-4678:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-05 1.54E-01 3.58E-05 3.30E-04 11 67 "PITPNC1,E2F6,PLEKHA1,FREM1,GRB10,IL6R,LIFR,PPP1R1A,BTBD3,SYT1,RPRM" MicroRNA hsa-miR-4780:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.64E-05 3.35E-04 13 92 "AQP6,CACNA1A,SLC16A4,SPATA2,LILRA2,KLHL23,MEIS1,SH3TC2,MYO18A,ZBTB43,PRRC2C,TAL1,ZDHHC20" MicroRNA hsa-miR-4300:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.64E-05 3.35E-04 13 92 "ELFN2,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,ERC1,NFASC,CAMTA2,APOM,PPIL6,RPRM" MicroRNA hsa-miR-20a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.64E-05 3.35E-04 13 92 "ZNF583,BID,DLGAP2,RTTN,HINFP,CSNK1G3,YTHDC1,NF1,PKIA,RPL15,STX1B,UGT8,FXR1" MicroRNA hsa-miR-506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.64E-05 3.35E-04 13 92 "LDHD,LONRF1,ENPP6,DNAJC27,LILRA2,SHISA6,KCNN1,STMN1,CHST6,MPP2,NPTX1,GPR137C,SLC38A1" MicroRNA hsa-miR-187-3p:TargetScan hsa-miR-187-3p TargetScan 2.88E-05 1.61E-01 3.74E-05 3.44E-04 6 18 "ACHE,LRFN1,NRG2,CRMP1,HIPK3,GTDC1" MicroRNA hsa-miR-1292:PITA hsa-miR-1292:PITA_TOP PITA 2.88E-05 1.61E-01 3.74E-05 3.44E-04 6 18 "STX16,CAMK2B,IP6K1,SLC12A6,CPEB3,SLC11A1" MicroRNA hsa-miR-4727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-05 1.62E-01 3.76E-05 3.46E-04 9 45 "UBXN2A,ZC3H11A,FARSB,GATM,RAB30,PKM,SMOX,ZNF621,ZXDA" MicroRNA hsa-miR-3197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-05 1.62E-01 3.76E-05 3.46E-04 9 45 "STOML1,NCOR2,DUSP9,GPR75,KAT7,IGF1,SEPHS1,SLC37A2,EVI5" MicroRNA hsa-miR-555:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.99E-05 1.67E-01 3.88E-05 3.57E-04 10 56 "CC2D2A,AQP6,CDR1,TVP23A,ZNF678,TTYH2,KANSL1,ZFP30,AMBRA1,ZNF610" MicroRNA hsa-miR-4490:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.99E-05 1.67E-01 3.88E-05 3.57E-04 10 56 "LONRF2,BAG4,KIT,MAT2A,EPDR1,PTPRE,C12orf49,SEMA6D,WBP2,NR2C2" MicroRNA hsa-miR-4700-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-05 1.70E-01 3.94E-05 3.63E-04 14 106 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,KCNN3,WBP1L,C12orf49,UNC5B,LAT2" MicroRNA hsa-miR-6507-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-05 1.70E-01 3.94E-05 3.63E-04 14 106 "SEMA6A,SEMA7A,CDC25B,DCAF8,FAM107B,FEM1B,IL6ST,NEK1,RASGEF1B,MCMBP,SPART,FAM208A,CLASP1,SMUG1" MicroRNA hsa-miR-593-5p:Functional MTI Functional MTI miRTarbase 3.08E-05 1.72E-01 3.99E-05 3.67E-04 12 80 "ADCY5,SLC24A4,CDC25B,PITPNM3,CELF1,PRUNE2,ANKRD36,MPRIP,PRRC2C,TRPS1,RPL7L1,MFF" MicroRNA hsa-miR-4769-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-05 1.72E-01 3.99E-05 3.67E-04 12 80 "LONRF2,NRG2,SEC24C,DCAF8,E2F6,GLUL,NEGR1,METTL21A,PMP22,CAMTA2,CLASP1,WNK2" MicroRNA hsa-miR-3141:mirSVR_highEffct hsa-miR-3141:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-05 1.72E-01 3.99E-05 3.67E-04 12 80 "MTMR7,VAC14-AS1,EPHB1,MED12L,CCDC184,GRM2,IL6ST,MBD1,PCSK5,MEG3,ANKRD36,SPTAN1" MicroRNA hsa-miR-570-3p:Functional MTI Functional MTI miRTarbase 3.09E-05 1.73E-01 4.00E-05 3.68E-04 19 179 "MTA3,IGDCC4,ISPD,BAG4,MYADM,SCML2,CELF1,SRRM4,TNRC6A,FUT10,GRB10,IL6R,KCNB1,ADAM22,SETD5,SGK1,CXXC4,SOX3,SLC38A1" MicroRNA hsa-miR-4482-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.15E-05 1.76E-01 4.08E-05 3.76E-04 13 93 "KIAA0319,DDX46,KLHL5,RCAN2,TNRC6A,IBA57,MBNL1,CCSER2,TRAPPC13,SALL1,MYO18A,KIF13A,KIAA0930" MicroRNA hsa-miR-921:Functional MTI Functional MTI miRTarbase 3.18E-05 1.78E-01 4.12E-05 3.79E-04 11 68 "CBR1,FOXN3,BAG4,MTX3,OCRL,ZFYVE21,KANSL1,RDX,ROBO1,TRA2B,SLC6A8" MicroRNA hsa-miR-3656:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-05 1.78E-01 4.12E-05 3.79E-04 11 68 "LTBP4,GAPVD1,RASSF2,GNG4,KAT7,KCNK3,ADAMTS17,SSBP2,ZNF708,ZNF154,EVI5" MicroRNA hsa-miR-653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-05 1.78E-01 4.12E-05 3.79E-04 11 68 "INSYN2B,SLC2A11,LONRF2,SRSF11,NSL1,DBN1,GLUL,SEC31A,SEPHS1,KIAA0930,RPL7L1" MicroRNA hsa-miR-105-5p:Functional MTI Functional MTI miRTarbase 3.38E-05 1.89E-01 4.37E-05 4.03E-04 14 107 "ZBTB10,NCOA1,ANKRD46,PLXNC1,RAB9B,COPS8,NPTX1,EPB41L4B,PEG10,TUBB2A,TOM1L2,ZNF225,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-3177:mirSVR_highEffct hsa-miR-3177:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.38E-05 1.89E-01 4.37E-05 4.03E-04 14 107 "ATP1B3,LY86,VCAN,PRELID3A,TRAF3IP2,FAM120B,ZIC5,PCDH9,FIGN,TTC17,MBD5,SYN1,PCDHA2,ZIC2" MicroRNA hsa-miR-4452:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-05 1.92E-01 4.44E-05 4.08E-04 15 121 "OSBPL8,ZNF578,PROM1,IBA57,LAMA2,PDPK1,PPP2R5E,SH3TC2,ZFP1,ZNF415,BDP1,PEG10,KCNT2,ZNF195,TFIP11" MicroRNA hsa-miR-520d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-05 1.92E-01 4.44E-05 4.08E-04 18 165 "MTA3,ST3GAL5,COPB2,GUCD1,SV2B,EDN1,STARD3NL,GABRB3,RNPS1,ZIC5,PDZRN4,PSD,RNASEL,ROBO1,ZNF415,FAM126B,NXT2,SMARCAD1" MicroRNA hsa-miR-219a-5p:Functional MTI Functional MTI miRTarbase 3.49E-05 1.95E-01 4.51E-05 4.15E-04 9 46 "CAMK2G,PUM1,EGFR,RAB30,RASSF8,MBNL1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-6720-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-05 1.95E-01 4.51E-05 4.15E-04 9 46 "SLC24A4,TXNDC16,RNF14,MRNIP,TUBD1,ATOH8,METTL21A,CBX5,CFAP298" MicroRNA hsa-miR-382-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-05 1.96E-01 4.52E-05 4.16E-04 12 81 "XKR4,CALM1,C8orf37,ENO2,APOPT1,TNRC6A,PRUNE2,MAP2,MYO6,CPEB4,CDK19,SPATA13" MicroRNA hsa-miR-718:mirSVR_highEffct hsa-miR-718:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-05 1.96E-01 4.53E-05 4.17E-04 10 57 "BCAS1,CALB2,CBLN1,PPT2,GDA,FRY,TMEM35A,COPS8,AFDN,MAPK9" MicroRNA hsa-miR-581:Functional MTI Functional MTI miRTarbase 3.51E-05 1.96E-01 4.53E-05 4.17E-04 10 57 "SPAG9,RUNX1T1,PPP1R16B,SPATA2,KNDC1,NTRK2,PURG,SATB1,DICER1,HNRNPA3" MicroRNA hsa-miR-6883-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.51E-05 1.96E-01 4.53E-05 4.17E-04 10 57 "AK2,LDHD,CACNA1G,RCAN1,CELSR3,PLEKHA1,BCAS3,ZNF793,NECAB1,AP3B2" MicroRNA hsa-miR-891b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.51E-05 1.96E-01 4.53E-05 4.17E-04 10 57 "MTX3,SYNCRIP,HHIPL1,IBA57,PTPRD,SALL1,PEX26,DIP2A,ZNF106,WNK3" MicroRNA hsa-miR-432-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-05 1.98E-01 4.56E-05 4.20E-04 13 94 "CASKIN1,OGT,DST,PDE4DIP,DNAJB6,STAMBP,PCLO,NUCB2,KIF21A,KDM4C,UNC5B,ADAMTS17,TUBB2A" MicroRNA hsa-miR-337-5p:PITA hsa-miR-337-5p:PITA_TOP PITA 3.60E-05 2.02E-01 4.65E-05 4.28E-04 8 36 "ARNTL,MARK4,CPEB2,SNX22,SGK1,NLGN1,SLC44A1,ZBTB38" MicroRNA hsa-miR-512-5p:Functional MTI Functional MTI miRTarbase 3.66E-05 2.05E-01 4.72E-05 4.34E-04 16 136 "ELFN2,OGT,CDC14B,ZNF583,CBFA2T2,NRXN3,ELMSAN1,ZNF585B,DOT1L,GPR75,IBA57,KCNJ5,MAT2A,VWA2,MTMR10,SLC2A5" MicroRNA hsa-miR-6804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-05 2.05E-01 4.72E-05 4.34E-04 11 69 "PTCHD1,DST,CFAP410,PPP1R16B,SIGLEC8,MTHFD2,PRRC2B,AGBL5,IBA57,GLDN,ZBTB43" MicroRNA hsa-miR-7106-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-05 2.05E-01 4.72E-05 4.34E-04 11 69 "TAOK1,C6orf89,CACNA1A,AKAP5,ZNF385A,HIPK3,KSR2,FIGN,KANSL3,ARC,NACC2" MicroRNA hsa-miR-148a-3p:Functional MTI Functional MTI miRTarbase 3.68E-05 2.06E-01 4.75E-05 4.37E-04 21 213 "ALCAM,TRMT9B,APC,STX16,CDC25B,QKI,PAN3,NEURL4,TNRC6A,MSL3,RASSF8,ZIC5,ZNF92,CNOT4,NPTX1,KANSL1,BTBD3,MYCBP2,CDK19,DICER1,FXR1" MicroRNA hsa-miR-199a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.72E-05 2.08E-01 4.79E-05 4.41E-04 18 166 "MAP4K3,DDR1,CDH2,CLTC,EDN1,ERBB2,DDX19B,XRRA1,PDE4D,TMOD2,POLR2F,ZNF844,SLC8A1,ZFP1,SNAP25,ZNF415,SIRT1,ZNF195" MicroRNA hsa-miR-6758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.76E-05 2.10E-01 4.84E-05 4.45E-04 14 108 "MTA3,CLTC,LETMD1,FEM1B,ANKMY1,GCK,PARD3B,UBE2QL1,IBA57,SMIM7,POU6F1,RDX,SETD5,PEG10" MicroRNA hsa-miR-504-5p:Functional MTI Functional MTI miRTarbase 3.76E-05 2.10E-01 4.84E-05 4.45E-04 14 108 "ZNF445,CNOT8,CRY2,MAT2A,P2RY13,PDE4A,PKD1,PSAT1,PRRT2,CSRNP3,ZC3H4,TRIM2,CLASP1,NR2C2" MicroRNA "TTCCGTT,MIR-191:MSigDB" "TTCCGTT,MIR-191:MSigDB" MSigDB 3.83E-05 2.14E-01 4.93E-05 4.54E-04 7 27 "ATP2B2,PHC2,NEURL4,NRCAM,TMOD2,PLCD1,MAP3K12" MicroRNA hsa-miR-199b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.96E-05 2.22E-01 5.10E-05 4.69E-04 12 82 "QKI,COL4A5,LIN54,RGS17,ZNF585B,FICD,PKM,MTRF1L,ATF7IP,ZNF106,RGMB,WNK2" MicroRNA hsa-miR-323a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.96E-05 2.22E-01 5.10E-05 4.69E-04 12 82 "ALCAM,ATP1B3,NDST3,ENTPD4,MTSS1L,ANKFY1,PLEC,MTRF1L,SKOR1,RBBP6,PRRT2,PEG10" MicroRNA hsa-miR-523:mirSVR_lowEffct hsa-miR-523:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.96E-05 2.22E-01 5.10E-05 4.69E-04 13 95 "CAMK2A,SNX29,ADGRV1,IP6K2,GHR,MYT1,NELL2,PCSK5,GPSM2,IRX1,ATAT1,RASA3,SNRPN" MicroRNA hsa-miR-887:mirSVR_highEffct hsa-miR-887:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.96E-05 2.22E-01 5.10E-05 4.69E-04 13 95 "CALM1,CCPG1,NCOR2,NELFCD,TRAF3IP2,GCNT2,GATD1,PTPRO,SAFB,SCN8A,PREX2,P2RY12,HNRNPA3" MicroRNA "GCGCTTT,MIR-518D:MSigDB" "GCGCTTT,MIR-518D:MSigDB" MSigDB 4.08E-05 2.28E-01 5.24E-05 4.82E-04 6 19 "ZNF608,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA "GCGCTTT,MIR-518C:MSigDB" "GCGCTTT,MIR-518C:MSigDB" MSigDB 4.08E-05 2.28E-01 5.24E-05 4.82E-04 6 19 "ZNF608,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA "GCGCTTT,MIR-518B:MSigDB" "GCGCTTT,MIR-518B:MSigDB" MSigDB 4.08E-05 2.28E-01 5.24E-05 4.82E-04 6 19 "ZNF608,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA hsa-miR-1202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.10E-05 2.29E-01 5.27E-05 4.85E-04 10 58 "SFMBT2,LDLRAD4,CBS,TMEM184B,BAG4,KIAA1958,PIK3R1,ZBTB43,ZNF28,LAMP5" MicroRNA hsa-miR-34c-3p:Functional MTI Functional MTI miRTarbase 4.10E-05 2.29E-01 5.27E-05 4.85E-04 10 58 "AXIN2,OGT,PHF12,INSYN2B,FOXN3,PLCXD3,ANKFY1,FYN,PPM1L,KIAA0930" MicroRNA "TCTGATC,MIR-383:MSigDB" "TCTGATC,MIR-383:MSigDB" MSigDB 4.18E-05 2.34E-01 5.36E-05 4.94E-04 9 47 "DCLK1,FOXN3,TAOK3,GABRB3,PCDH17,SLC2A6,MAPKAP1,STRN3,SHMT2" MicroRNA hsa-miR-4638-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-05 2.34E-01 5.36E-05 4.94E-04 9 47 "APBB2,CDC14B,DPY19L3,MYRF,TMEM184B,IGDCC3,STX1B,CRTC1,CELF4" MicroRNA hsa-miR-663:PITA hsa-miR-663:PITA_TOP PITA 4.18E-05 2.34E-01 5.36E-05 4.94E-04 9 47 "ZNF385A,GRIN2D,CAMK2N2,MAPT,NFIX,PPP5C,BTBD3,SZT2,AMACR" MicroRNA hsa-miR-31-3p:Functional MTI Functional MTI miRTarbase 4.20E-05 2.35E-01 5.39E-05 4.97E-04 11 70 "BACH1,FBXL5,PAX6,PDE4D,EPB41L4B,NLGN1,PUM2,DICER1,RPL7L1,RICTOR,SLC38A1" MicroRNA hsa-miR-6871-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-05 2.48E-01 5.69E-05 5.24E-04 13 96 "DDR1,TOGARAM2,FEM1B,GOLGA7,SYNPO,PDPK1,GLDN,SGK1,ZC3H4,SLC37A2,CLASP1,ZNF45,GAN" MicroRNA hsa-miR-339-3p:mirSVR_highEffct hsa-miR-339-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.48E-05 2.50E-01 5.74E-05 5.29E-04 12 83 "UNC79,CFLAR,PDE4DIP,TMCC2,DNM1,IP6K2,CRCP,FAM19A2,NF1,ARX,DDN,ADHFE1" MicroRNA hsa-miR-6889-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-05 2.50E-01 5.74E-05 5.29E-04 12 83 "CASKIN1,LTBP4,PDZD4,TMEM184B,ZNF385A,SEC16A,SHISA6,SLC11A2,PLIN1,EMID1,CLIP1,SBF1" MicroRNA hsa-miR-6729-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-05 2.50E-01 5.74E-05 5.29E-04 12 83 "CASTOR3,CLDN10,IGDCC3,SEC31B,TOM1,ANKMY1,ATP13A4,NELL2,OPRL1,SDK2,WDR37,STAC2" MicroRNA hsa-miR-6777-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-05 2.50E-01 5.74E-05 5.29E-04 12 83 "CASKIN1,LTBP4,PDZD4,TMEM184B,ZNF385A,SEC16A,SHISA6,SLC11A2,PLIN1,EMID1,CLIP1,SBF1" MicroRNA hsa-miR-937-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-05 2.50E-01 5.74E-05 5.29E-04 12 83 "OGT,UBXN2A,SLC12A6,ANKRD46,RNF165,HSPA4L,SHMT2,ST6GAL1,SEPHS1,SPART,CYB561A3,JMJD1C" MicroRNA hsa-miR-1972:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.58E-05 2.56E-01 5.87E-05 5.40E-04 15 124 "RNF157,LTBP4,SHROOM2,YTHDC1,DNAJC27,POLR1B,RNF165,KCTD15,C12orf49,SH3BP2,R3HDM2,EPN2,ZNF621,SLC37A2,TMEM237" MicroRNA hsa-miR-649:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.78E-05 2.67E-01 6.12E-05 5.64E-04 10 59 "SLC2A11,CCNT1,YTHDC1,YAF2,LILRA2,ZIC5,MYO5A,SLC2A5,PUM2,ARL10" MicroRNA hsa-miR-4433a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-05 2.69E-01 6.16E-05 5.67E-04 11 71 "MTUS1,MYADM,TNK2,SYNPO,SLC6A17,PSAT1,NDUFS7,MAP6D1,WBP2,VLDLR,ZNF24" MicroRNA hsa-miR-124-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-05 2.69E-01 6.16E-05 5.67E-04 11 71 "ACHE,TAOK1,PLEKHA1,SUCO,UBE2E3,PSAT1,SH3TC2,REV3L,ASTN2,NR2E1,NELFE" MicroRNA hsa-miR-2681-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.98E-05 2.78E-01 6.37E-05 5.87E-04 9 48 "TBPL1,SYNCRIP,SMC2,ZNF678,OLA1,GTDC1,PGBD4,BDP1,ZNF28" MicroRNA hsa-miR-4317:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.98E-05 2.78E-01 6.37E-05 5.87E-04 9 48 "ELFN2,MRO,MIER3,EID2B,PIK3R1,PNMA8A,ZNF415,RBM26,SLC38A1" MicroRNA hsa-miR-3686:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.05E-05 2.83E-01 6.46E-05 5.95E-04 12 84 "RASL11B,FOXN3,SOCS5,DNAJB6,EIF4G2,MRVI1,GRIK4,NPTX2,PBRM1,CHD9,TET1,EPC1" MicroRNA hsa-miR-1295b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.05E-05 2.83E-01 6.46E-05 5.95E-04 12 84 "DGKG,FKTN,ZBED3,NEU3,GCK,XRN1,TMEM38A,RBBP6,CSRNP3,DOCK9,WRN,CADM2" MicroRNA hsa-miR-4733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.05E-05 2.83E-01 6.46E-05 5.95E-04 12 84 "SLC24A4,PYGO1,SPATA2,YTHDC1,HEYL,RAB30,SHC3,MYO5A,SCP2,PEX26,TMCC1,ZNF621" MicroRNA hsa-miR-605-5p:Functional MTI Functional MTI miRTarbase 5.11E-05 2.86E-01 6.53E-05 6.02E-04 14 111 "SPOP,ABCD2,CACNA1A,IP6K1,RCAN1,AASDH,EDN3,KIAA1958,ZNF678,SFXN5,SULF2,NR2C2,RTN4,GAN" MicroRNA hsa-miR-602:PITA hsa-miR-602:PITA_TOP PITA 5.46E-05 3.05E-01 6.98E-05 6.42E-04 8 38 "ZBTB10,DPP6,RASGRP2,TAOK3,CHL1,MID1,NRCAM,GPR85" MicroRNA hsa-miR-3117-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-05 3.05E-01 6.98E-05 6.42E-04 8 38 "SPOP,ABCD2,CREM,LONRF1,SMAD1,TRIM2,UBTF,UGT8" MicroRNA hsa-miR-5000-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.49E-05 3.07E-01 7.01E-05 6.46E-04 11 72 "LDHD,KALRN,ARHGAP22,ENPP6,KCNN1,GPR137C,PKM,SMOX,ZC3H4,SLC44A1,WBP2" MicroRNA hsa-miR-4436a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.49E-05 3.07E-01 7.01E-05 6.46E-04 11 72 "LDHD,KALRN,ARHGAP22,ENPP6,KCNN1,GPR137C,PKM,SMOX,ZC3H4,SLC44A1,WBP2" MicroRNA hsa-miR-4727-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.49E-05 3.07E-01 7.01E-05 6.46E-04 11 72 "TOGARAM2,CPS1,BOC,YTHDC1,EDN1,EDN3,EPB41,CELF1,ZNF546,PLCL1,AGMO" MicroRNA hsa-miR-1225-3p:PITA hsa-miR-1225-3p:PITA_TOP PITA 5.49E-05 3.07E-01 7.01E-05 6.46E-04 11 72 "PITPNM2,SH2B1,DUSP9,GABRB3,CPLX2,TNRC6A,NEFM,RORB,MYO18A,TEX2,AMACR" MicroRNA hsa-miR-7843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.49E-05 3.07E-01 7.01E-05 6.46E-04 11 72 "SFMBT2,DGKI,TOM1,ZNF391,ATP13A4,PCDH9,PDE3A,KLHL11,ANKRD24,ZNF225,STOX2" MicroRNA hsa-miR-562:Functional MTI Functional MTI miRTarbase 5.52E-05 3.09E-01 7.05E-05 6.49E-04 15 126 "CDC14B,CCNT1,FOXN3,CREM,EIF4G2,RGS17,SLC43A2,EYA1,TRMO,ZBED3,TXNL4A,KAT7,FICD,PSAT1,PGBD4" MicroRNA hsa-miR-1180:PITA hsa-miR-1180:PITA_TOP PITA 5.64E-05 3.16E-01 7.20E-05 6.63E-04 6 20 "IGDCC3,HPCAL4,PPP2R5E,KANSL1,CEP41,HECW1" MicroRNA hsa-miR-376a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 5.64E-05 3.16E-01 7.20E-05 6.63E-04 14 112 "MYRF,SRSF11,RIMS2,YAF2,AMOTL2,CYP27C1,SHC3,PFKFB2,PIK3R1,ZNF426,ZNF844,ZNF667,SLC35G2,ZNF781" MicroRNA hsa-miR-541-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.18E-01 7.26E-05 6.68E-04 12 85 "TAOK1,OGT,LDHD,ARHGEF7,ELMSAN1,C8orf37,CELF1,DOT1L,ZNF426,AKTIP,TUBB2A,UBE3A" MicroRNA hsa-miR-148a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.18E-01 7.26E-05 6.68E-04 12 85 "CACNA1A,C1orf52,CST3,BOC,MTX3,RCAN2,APC2,SCML2,AFF2,FUT10,PDPK1,TNS1" MicroRNA hsa-miR-1183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.18E-01 7.26E-05 6.68E-04 12 85 "ZNF608,HECTD1,IST1,FAM107B,PLEKHA1,TMEM164,CELF1,PDPK1,HSPA4L,ZHX3,ERBIN,AMACR" MicroRNA hsa-miR-6753-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.18E-01 7.26E-05 6.68E-04 12 85 "PHF12,ATP1A1,IPCEF1,SCML2,DLC1,BRSK1,PRRC2B,DDX19B,TTYH2,PALM,ALG9,MPPE1" MicroRNA "GCTGAGT,MIR-512-5P:MSigDB" "GCTGAGT,MIR-512-5P:MSigDB" MSigDB 5.90E-05 3.30E-01 7.52E-05 6.92E-04 9 49 "DLGAP2,EMX2,SOX21,NFIX,PIK3R1,PRIMA1,COPZ1,CHD9,FBXW11" MicroRNA hsa-miR-376a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-05 3.30E-01 7.52E-05 6.92E-04 9 49 "BACH1,SRSF11,BAG4,TUBD1,RAB30,KPNA5,CLIP1,CHD9,CBX5" MicroRNA hsa-miR-6762-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-05 3.30E-01 7.52E-05 6.92E-04 9 49 "NCOA1,SV2B,MRVI1,SRRM4,GPT2,CREG2,MAP4,NFIX,ZNF610" MicroRNA hsa-miR-524-5p:Functional MTI Functional MTI miRTarbase 5.94E-05 3.33E-01 7.57E-05 6.97E-04 18 172 "MTA3,ST3GAL5,COPB2,GUCD1,SV2B,EDN1,STARD3NL,GABRB3,RNPS1,ZIC5,PDZRN4,PSD,RNASEL,ROBO1,ZNF415,FAM126B,NXT2,SMARCAD1" MicroRNA hsa-miR-6787-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.05E-05 3.38E-01 7.71E-05 7.10E-04 15 127 "PTCHD1,PDZD4,PRX,ARHGDIA,EVI5L,ZNF385A,MYADM,MTSS1L,C12orf49,PTGR2,SBF1,PEX26,WBP2,VGF,ZNF154" MicroRNA hsa-miR-542-5p:mirSVR_highEffct hsa-miR-542-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.14E-05 3.43E-01 7.82E-05 7.20E-04 13 99 "ARHGEF1,PPT2,SULT4A1,FDFT1,CLASRP,MATK,FXYD7,ADHFE1,SYN1,RNF216P1,MTMR14,HSPBP1,NETO1" MicroRNA hsa-miR-455-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.14E-05 3.43E-01 7.82E-05 7.20E-04 13 99 "RUNX1T1,QKI,RASSF2,TMEM170A,PIK3R1,PTPRB,ZNF354C,SEPHS1,SOX11,ARC,MGRN1,ZNF138,ZFAND5" MicroRNA hsa-miR-4708-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.20E-05 3.47E-01 7.89E-05 7.27E-04 16 142 "MTA3,CDC25B,JAKMIP2,PLEKHA1,GLUL,SHISA6,ZNF426,PPP2R5E,ELP2,SCN2B,FAM102A,NUBPL,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-6884-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.25E-05 3.50E-01 7.96E-05 7.33E-04 11 73 "TAOK1,ATP2A2,MTMR3,TOGARAM2,HIPK3,IDH3B,MYO5A,TRIM67,NR2E1,NR2C2,ZIC2" MicroRNA hsa-miR-1470:mirSVR_highEffct hsa-miR-1470:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.25E-05 3.50E-01 7.96E-05 7.33E-04 11 73 "GALNT16,KSR1,DDR1,DPP6,RAB30,C2orf72,ZNF678,SIRT2,KDM4C,PEG10,CLIP2" MicroRNA hsa-miR-4536-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-05 3.52E-01 8.00E-05 7.37E-04 5 13 "ISPD,DBN1,STX1B,NACC2,USP1" MicroRNA hsa-miR-1250:PITA hsa-miR-1250:PITA_TOP PITA 6.31E-05 3.53E-01 8.03E-05 7.39E-04 7 29 "ATP1A1,CHN1,ZNF827,PTPRO,SS18,REEP1,PHTF2" MicroRNA hsa-miR-770-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-05 3.58E-01 8.13E-05 7.49E-04 12 86 "CS,GOLGA7,ERCC2,ADAM22,ZNF426,FBXW7,MEG3,BTBD3,ZNF667,RCOR3,ZNF23,ZNF138" MicroRNA hsa-miR-3188:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-05 3.58E-01 8.13E-05 7.49E-04 12 86 "SLC24A4,CEP126,ARHGDIA,MTMR3,CCNT1,CRY2,RIMS4,KIAA0408,SRCAP,SETD5,DDN,URM1" MicroRNA hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-05 3.59E-01 8.15E-05 7.50E-04 10 61 "TAOK1,C6orf89,SCARA3,RNF165,MAPT,PEX2,PRRT2,CLIP1,SARS,NACC2" MicroRNA hsa-miR-4501:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-05 3.59E-01 8.15E-05 7.50E-04 10 61 "FMNL2,INTS2,USP37,E2F6,EIF5,KATNAL1,IL6ST,PPM1L,PEX26,SIN3B" MicroRNA hsa-miR-1915-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-05 3.59E-01 8.15E-05 7.50E-04 10 61 "TNRC6C,CALM1,NRXN3,TPP1,CRCP,SHISA6,MAPT,TRIM67,ZBTB43,UBE2H" MicroRNA hsa-miR-3681-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-05 3.59E-01 8.15E-05 7.50E-04 10 61 "FARSB,MALT1,NXPH3,PACSIN2,CEP97,ZNF621,TRIM2,PCDHA6,FRYL,ZXDA" MicroRNA hsa-miR-6849-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-05 3.59E-01 8.15E-05 7.50E-04 10 61 "FARSB,MALT1,NXPH3,PACSIN2,CEP97,ZNF621,TRIM2,PCDHA6,FRYL,ZXDA" MicroRNA hsa-miR-95:mirSVR_highEffct hsa-miR-95:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.63E-05 3.71E-01 8.41E-05 7.74E-04 15 128 "PPP4R4,RGS6,HDAC9,ADGRV1,GCNT2,KNDC1,MID1,PURG,PRKACB,QDPR,GTDC1,C9orf85,DCBLD1,TTC3,PDSS2" MicroRNA hsa-miR-4690-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.82E-05 3.82E-01 8.66E-05 7.97E-04 13 100 "KALRN,CS,HEYL,EBI3,LYVE1,NCKAP1L,METTL21A,MMP17,VWA2,ZDHHC8,PRRT2,PBLD,KIAA0930" MicroRNA hsa-let-7f-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.87E-05 3.84E-01 8.71E-05 8.02E-04 14 114 "SPAG9,C1orf52,COPB2,MYADM,SEMA4D,GABRG1,ZNF181,ZNF546,NCOA7,MBNL1,HNRNPM,CNKSR2,DIP2A,GPRIN3" MicroRNA hsa-miR-98-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.87E-05 3.84E-01 8.71E-05 8.02E-04 14 114 "SPAG9,C1orf52,COPB2,MYADM,E2F5,SEMA4D,GABRG1,ZNF181,ZNF546,NCOA7,MBNL1,CNKSR2,DIP2A,GPRIN3" MicroRNA hsa-miR-3689b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.90E-01 8.82E-05 8.12E-04 9 50 "ZBED3,CELF1,ZNF181,CLIP1,CSRNP3,FAM126B,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-3689a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.90E-01 8.82E-05 8.12E-04 9 50 "ZBED3,CELF1,ZNF181,CLIP1,CSRNP3,FAM126B,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-5571-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.90E-01 8.82E-05 8.12E-04 9 50 "RGS6,TNK2,FREM1,NELL2,KANSL1,FITM2,SCN2B,ADAMTS17,ZNF34" MicroRNA hsa-miR-3689e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.90E-01 8.82E-05 8.12E-04 9 50 "ZBED3,CELF1,ZNF181,CLIP1,CSRNP3,FAM126B,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-1298-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.90E-01 8.82E-05 8.12E-04 9 50 "ZNF385A,UFM1,CRCP,GLUL,MAT2A,PPP1R1A,PTPRE,PEX26,TMPO" MicroRNA hsa-miR-187:mirSVR_highEffct hsa-miR-187:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.98E-05 3.91E-01 8.85E-05 8.15E-04 19 190 "NDRG3,LRFN1,ARNTL,ARRB1,CCDC74A,CNRIP1,HIPK3,GAD1,PPARGC1A,GRIA2,CLASRP,MAN1B1,NME9,SMAD1,THYN1,TREM2,BDNF-AS,RBM26,RICTOR" MicroRNA hsa-miR-4461:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "SEMA7A,NCOA1,CLOCK,GUCD1,GOLT1B,MRO,ZNF589,ZNF678,CHIC1,ZNF426,VSNL1" MicroRNA hsa-miR-203a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "BRAP,BCL7A,CACNA1A,PTBP2,CD38,DOCK4,XRRA1,ZNF426,NWD1,ZNF28,CIAPIN1" MicroRNA hsa-miR-518c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "TMEM184B,IGDCC3,KLHL23,PDE3A,PDE1B,SEPT4,NCBP3,R3HDM2,ZNF621,SSBP2,CLDND1" MicroRNA hsa-miR-502-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "CA12,DCTN2,MTHFD2,SESN1,AGBL5,IBA57,MSI1,PEG10,ZBTB43,SSTR1,PLCB1" MicroRNA hsa-miR-502-5p:Functional MTI Functional MTI miRTarbase 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "TNRC6C,CALM1,TPP1,KMT5B,HAS2,SHISA6,SHISAL1,NFYA,ATXN7,TRIM67,NACC2" MicroRNA hsa-miR-125b-1*:mirSVR_highEffct hsa-miR-125b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.11E-05 3.98E-01 8.99E-05 8.28E-04 11 74 "NDRG2,TXNDC16,BCAS1,CNTN1,USP6NL,MATR3,SRCAP,RASSF8,NCOA7,MARK1,NF1" MicroRNA hsa-miR-572:mirSVR_highEffct hsa-miR-572:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.18E-05 4.01E-01 9.07E-05 8.35E-04 12 87 "PPFIA3,ARHGEF7,TAOK2,BRD8,CCDC184,CLASRP,ATXN2L,TMEM260,ATXN7,SEPT8,DOCK9,ANKS1B" MicroRNA hsa-miR-6781-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.18E-05 4.01E-01 9.07E-05 8.35E-04 12 87 "TXNDC16,APPL1,SEPT9,TPPP,NFIX,NCBP3,ZKSCAN3,SP2,MPRIP,STX1A,BHLHB9,TMEM63C" MicroRNA hsa-miR-8071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.18E-05 4.01E-01 9.07E-05 8.35E-04 12 87 "TAOK1,NRXN3,TMEM184B,DUSP9,MRPL10,MTHFD2,PPM1L,MKLN1,PLXNB1,GALNT10,STUM,PEG10" MicroRNA hsa-miR-6872-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.25E-05 4.06E-01 9.16E-05 8.44E-04 15 129 "RNF14,HINFP,DNAJB6,TBC1D16,FKTN,PCYOX1,PDLIM5,TRAF3IP2,NKD1,ZDHHC14,PEX26,SLC37A2,GPRIN3,BCL2L13,CFAP298" MicroRNA hsa-miR-663a:Functional MTI Functional MTI miRTarbase 7.34E-05 4.11E-01 9.28E-05 8.54E-04 16 144 "PTCHD1,PDZD4,APC,PRX,ARHGDIA,EVI5L,ZNF385A,MYADM,MTSS1L,C12orf49,PTGR2,SBF1,PEX26,WBP2,VGF,ZNF154" MicroRNA hsa-miR-190b:Functional MTI Functional MTI miRTarbase 7.41E-05 4.14E-01 9.36E-05 8.62E-04 10 62 "ZNF608,STAMBP,MSANTD4,RAB30,TNRC6A,KCNMB4,IGF1,IL6ST,TRA2B,BCL2L13" MicroRNA hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 7.57E-05 4.24E-01 9.57E-05 8.81E-04 13 101 "GALNT16,BRAP,DST,HDAC4,ZC3H11A,GALC,RAB30,MYO6,PAX6,ZNF426,MEG3,CNKSR2,FXR1" MicroRNA hsa-miR-6812-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.57E-05 4.24E-01 9.57E-05 8.81E-04 13 101 "CRLF1,ZNF385A,IP6K1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MPP2,MAPK10,KLHDC8A,ATXN2,UBTF" MicroRNA hsa-miR-8057:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.80E-05 4.36E-01 9.84E-05 9.06E-04 17 160 "XKR4,ESYT2,AKAP5,AKAP12,CRY2,GOLGA7,PCYOX1,PDLIM5,CRCP,DBF4,LIMS1,SMOX,ZNF430,SLC8A1,POGZ,ZNF106,TRPS1" MicroRNA hsa-miR-3664-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.02E-05 4.49E-01 1.01E-04 9.32E-04 18 176 "SLC24A4,CDC14B,ZNF583,NDST3,NRXN3,PPP1R16B,YTHDC1,ELMSAN1,SV2B,ZNF585B,CAMKK2,GPR75,KCNJ5,PPM1L,PLEC,PPP2R5E,MTMR10,SLC2A5" MicroRNA hsa-miR-1283:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.04E-05 4.50E-01 1.01E-04 9.34E-04 12 88 "ENPP6,FREM1,TCERG1,RNPS1,FICD,MARK1,GPR137C,PKIA,PTPRB,CLASP1,SLC44A1,SPATA13" MicroRNA hsa-miR-4508:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.04E-05 4.50E-01 1.02E-04 9.34E-04 8 40 "AMH,PRX,ARHGDIA,RGS6,IRAK3,ZNF426,PEX26,TMEM63C" MicroRNA hsa-miR-1296:PITA hsa-miR-1296:PITA_TOP PITA 8.04E-05 4.50E-01 1.02E-04 9.34E-04 8 40 "PTCHD1,INTS2,ADGRB1,CAMK2G,ZNF521,DCAF8,TMEM255A,SYN1" MicroRNA hsa-miR-453:PITA hsa-miR-453:PITA_TOP PITA 8.06E-05 4.51E-01 1.02E-04 9.35E-04 11 75 "PTBP2,CAMK2B,CALCRL,PAN3,INSM1,MXI1,NDP,ERC1,FBXW11,TCF12,LRRC8A" MicroRNA hsa-miR-489-3p:Functional MTI Functional MTI miRTarbase 8.06E-05 4.51E-01 1.02E-04 9.35E-04 11 75 "KIAA0040,FEM1B,FRY,IQCG,ZBED3,ADAM28,SPIN1,GNAL,FNIP1,RPL7L1,CADM2" MicroRNA hsa-let-7b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.31E-05 4.65E-01 1.05E-04 9.65E-04 14 116 "SPAG9,C1orf52,COPB2,MYADM,SEMA4D,GABRG1,LRRC75A,ZNF181,ZNF546,NCOA7,MBNL1,CNKSR2,DIP2A,GPRIN3" MicroRNA hsa-miR-1255a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-05 4.70E-01 1.06E-04 9.74E-04 13 102 "TAOK1,GAS7,CPS1,SPATA2,C8orf37,KAT7,GPR137C,NCR3LG1,C1orf109,NKAIN1,FAM102A,NMNAT2,TROVE2" MicroRNA hsa-miR-6737-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-05 4.70E-01 1.06E-04 9.74E-04 13 102 "CRLF1,ZNF385A,IP6K1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MPP2,MAPK10,KLHDC8A,ATXN2,UBTF" MicroRNA hsa-miR-1255b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-05 4.70E-01 1.06E-04 9.74E-04 13 102 "TAOK1,GAS7,CPS1,SPATA2,C8orf37,KAT7,GPR137C,NCR3LG1,C1orf109,NKAIN1,FAM102A,NMNAT2,TROVE2" MicroRNA hsa-miR-5585-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.52E-05 4.77E-01 1.07E-04 9.87E-04 10 63 "JAZF1,CCNT1,BAG4,DBN1,F5,MIER3,STMN1,PDE3A,OLA1,HECW1" MicroRNA hsa-miR-4312:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.52E-05 4.77E-01 1.07E-04 9.87E-04 10 63 "CREM,CRCP,MAPT,P2RX7,GPR137C,ZNF426,HSPA4L,ZFP1,GPRIN3,VLDLR" MicroRNA hsa-miR-3679-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.52E-05 4.77E-01 1.07E-04 9.87E-04 10 63 "GAPVD1,SYNCRIP,KCNMB4,MAT2A,NUCB2,ZNF426,C1orf109,MRAS,HSPA4L,TPM1" MicroRNA hsa-miR-488-3p:Functional MTI Functional MTI miRTarbase 8.65E-05 4.84E-01 1.09E-04 1.00E-03 15 131 "BAG4,FAM169A,PITPNC1,FUT10,HAS2,TJAP1,PAX6,INAVA,ZNF621,ERBIN,PCDHA6,ZMAT3,CBX5,TUBB2A,UBC" MicroRNA hsa-miR-4464:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.98E-05 5.03E-01 1.13E-04 1.04E-03 12 89 "MTUS1,ENPP6,ERBB2,GLI2,SLC2A6,ELOVL5,GLIPR1L2,CNNM2,MARCH1,SEPHS1,TNS1,WRN" MicroRNA hsa-miR-639:mirSVR_highEffct hsa-miR-639:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.10E-05 5.09E-01 1.15E-04 1.05E-03 17 162 "LRFN1,SEMA7A,BCL7A,DDR1,RTTN,ZNF585B,ZNF276,ZBTB49,MAP4,DNHD1,KANSL1,TMEM260,ZNF532,ATXN7,NUBPL,SOX3,ZEB1" MicroRNA hsa-miR-7849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.11E-05 5.10E-01 1.15E-04 1.06E-03 11 76 "TMTC1,ASB3,FDFT1,ZNF589,SEMA4D,JKAMP,ZNF546,PDE3A,PKIA,ACSS3,TSN" MicroRNA hsa-miR-4732-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.11E-05 5.10E-01 1.15E-04 1.06E-03 11 76 "RGS11,ZNF385A,SMC2,NEGR1,SLC35G1,CYP27C1,MAT2A,KSR2,UBR7,ZNF177,DHX33" MicroRNA hsa-miR-874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.11E-05 5.10E-01 1.15E-04 1.06E-03 11 76 "TRMT9B,TOM1,MTSS1L,CEP78,CYP27C1,NFIX,PDE4A,KCNIP3,TRIM67,MGAT5B,INTS3" MicroRNA hsa-miR-6817-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.11E-05 5.10E-01 1.15E-04 1.06E-03 11 76 "ARSE,QKI,BOC,EDN1,EDN3,EPB41,CELF1,ZNF546,PLCL1,RXRA,ZNF106" MicroRNA hsa-miR-3944-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.13E-05 5.11E-01 1.15E-04 1.06E-03 14 117 "ST3GAL5,TBPL1,SPATA2,ENPP6,AFF2,TNRC6A,MAT2A,AFF1,NBL1,RBBP6,CLIP1,MGRN1,NACC2,ZNF138" MicroRNA hsa-miR-6877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.13E-05 5.11E-01 1.15E-04 1.06E-03 14 117 "AP1M1,RIPOR2,MRNIP,RGS17,FGF1,CELF1,SRCAP,NEGR1,ZNF426,ZNF667,SNAP25,PEG10,ERBIN,KLHL7" MicroRNA hsa-miR-6819-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.29E-05 5.20E-01 1.17E-04 1.08E-03 13 103 "CRLF1,ZNF385A,IP6K1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MPP2,MAPK10,KLHDC8A,ATXN2,UBTF" MicroRNA hsa-miR-1254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.43E-05 5.28E-01 1.19E-04 1.09E-03 15 132 "CLK4,HECW2,APBB2,CDC14B,KLHL3,PHC2,ERBB2,ANKMY1,PCYOX1,NXPH3,C2orf72,PKM,RBBP6,ANKRD24,PARD3" MicroRNA hsa-miR-127-3p:PITA hsa-miR-127-3p:PITA_TOP PITA 9.49E-05 5.31E-01 1.19E-04 1.10E-03 5 14 "SEPT7,RIMS4,AGAP3,BCAS3,SCN8A" MicroRNA hsa-miR-3162-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.58E-05 5.36E-01 1.20E-04 1.11E-03 9 52 "RGS6,TM9SF4,RASA4,GOLGA7,ANKFY1,SLC25A36,NEK4,ZNF34,FAM198A" MicroRNA hsa-miR-3617-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.58E-05 5.36E-01 1.20E-04 1.11E-03 9 52 "FAM49B,MTHFD2,SEMA6D,CPEB4,ANKRD28,KIAA0930,WRN,GDPD5,URM1" MicroRNA hsa-miR-519e-3p:Functional MTI Functional MTI miRTarbase 9.58E-05 5.36E-01 1.20E-04 1.11E-03 9 52 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,FLT1,AFF1,ADAM22,ZC3H12B" MicroRNA hsa-miR-4704-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.68E-05 5.41E-01 1.21E-04 1.12E-03 8 41 "FMNL2,CAMK2G,PUM1,EIF1,ADAM22,PEG10,CSMD1,MKRN3" MicroRNA hsa-miR-4804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.77E-05 5.47E-01 1.22E-04 1.13E-03 10 64 "AFF2,CELF1,IL6ST,KLHL11,GSTCD,GLDN,COPZ1,TRIM67,ZMAT3,RASD2" MicroRNA hsa-miR-190a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 9.77E-05 5.47E-01 1.22E-04 1.13E-03 10 64 "ZNF608,STAMBP,MSANTD4,RAB30,TNRC6A,KCNMB4,IGF1,IL6ST,TRA2B,BCL2L13" MicroRNA hsa-miR-3936:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.77E-05 5.47E-01 1.22E-04 1.13E-03 10 64 "IP6K1,POLL,FRMD5,ZNF678,MAT2A,SH3TC2,TMCC1,AP4E1,KLC2,GAN" MicroRNA hsa-miR-3156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.77E-05 5.47E-01 1.22E-04 1.13E-03 10 64 "PROM1,CD86,LILRA2,ATXN2L,ZIC5,PCSK1,SLC37A2,ITGB3BP,SLC44A1,ARL10" MicroRNA "GGTAACC,MIR-409-5P:MSigDB" "GGTAACC,MIR-409-5P:MSigDB" MSigDB 9.98E-05 5.58E-01 1.25E-04 1.15E-03 7 31 "CAMK2G,KMT5B,RASL12,PURG,TRPS1,ZIC1,TRIM9" MicroRNA hsa-miR-518e:PITA hsa-miR-518e:PITA_TOP PITA 9.98E-05 5.58E-01 1.25E-04 1.15E-03 7 31 "ZNF608,ZNF521,ZNF385A,SOCS5,EGR3,NEXMIF,MCF2L" MicroRNA hsa-miR-744-5p:TargetScan hsa-miR-744-5p TargetScan 9.98E-05 5.58E-01 1.25E-04 1.15E-03 7 31 "BIN1,KCNAB3,EGR3,GRIN2D,DBNL,NFIX,PPP5C" MicroRNA hsa-miR-4748:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-04 5.61E-01 1.26E-04 1.16E-03 12 90 "MTUS1,ENPP6,ERBB2,GLI2,SLC2A6,ELOVL5,GLIPR1L2,CNNM2,MARCH1,SEPHS1,TNS1,WRN" MicroRNA hsa-miR-7113-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-04 5.70E-01 1.27E-04 1.17E-03 16 148 "C6orf89,BCL7A,TMEM184B,IPCEF1,ELMSAN1,KLHL3,SCML2,NFIX,RNH1,HES6,MAPKBP1,NFASC,SIN3B,PCDHA6,TSPAN11,MPPE1" MicroRNA hsa-miR-6768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-04 5.70E-01 1.27E-04 1.17E-03 16 148 "SEMA4G,ARHGDIA,CCAR2,ZNF583,RASSF2,PITPNC1,SPECC1,FAM120B,PLCL1,CNNM2,ZMAT4,ZNF532,UNC5B,NACC2,MTCH1,DHX33" MicroRNA hsa-miR-339-3p:PITA hsa-miR-339-3p:PITA_TOP PITA 1.02E-04 5.71E-01 1.28E-04 1.18E-03 6 22 "RNF150,ADGRB1,RGS6,ARX,DDN,RIMBP2" MicroRNA hsa-miR-6503-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-04 5.71E-01 1.28E-04 1.18E-03 6 22 "RPS6KL1,CYP27C1,MAPT,PDPK1,ZMAT4,STUM" MicroRNA hsa-miR-4527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-04 5.71E-01 1.28E-04 1.18E-03 6 22 "RPS6KL1,CYP27C1,MAPT,PDPK1,ZMAT4,STUM" MicroRNA hsa-miR-99a-5p:Functional MTI Functional MTI miRTarbase 1.03E-04 5.75E-01 1.29E-04 1.18E-03 15 133 "ATP1A1,DOCK11,MTMR3,FAM171B,PUM1,DDX46,MED12,FGFR3,TPPP3,NFU1,GNAL,N6AMT1,RUNDC3B,RPL7L1,SPIRE1" MicroRNA hsa-miR-888-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.76E-01 1.29E-04 1.18E-03 11 77 "CDK13,FOXN3,CNN3,ARHGEF6,SLC12A6,CELSR3,RAB9B,RNPS1,SMIM11A,LIMCH1,TBC1D15" MicroRNA hsa-miR-6774-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-04 6.00E-01 1.34E-04 1.24E-03 4 8 "CCPG1,MRO,DCTN4,KDM2B" MicroRNA hsa-miR-6819-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-04 6.14E-01 1.37E-04 1.26E-03 14 119 "AP1M1,RIPOR2,MRNIP,RGS17,FGF1,CELF1,SRCAP,NEGR1,ZNF426,ZNF667,SNAP25,PEG10,ERBIN,KLHL7" MicroRNA hsa-miR-29b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-04 6.14E-01 1.37E-04 1.26E-03 14 119 "SORCS2,MARCH4,CDK13,DYNLL1,STX16,DLC1,TCERG1,LSAMP,GPR155,KITLG,SH3BP2,ZNF415,NACC2,ZNF195" MicroRNA hsa-miR-4309:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-04 6.14E-01 1.37E-04 1.26E-03 14 119 "SEMA7A,DNAL1,DNAJB6,CAMKK2,GLUL,ZNF426,ELP2,SCN2B,HSPA4L,NUBPL,FAM126B,CDK19,KIAA0930,ZNF708" MicroRNA hsa-miR-3667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 9 53 "UBXN2A,ANKMY1,SLC11A2,ZNF844,KLHDC8A,ASAP3,SP4,CRTC1,TRPS1" MicroRNA "CCATCCA,MIR-432:MSigDB" "CCATCCA,MIR-432:MSigDB" MSigDB 1.12E-04 6.25E-01 1.39E-04 1.28E-03 9 53 "HECW2,PCDH10,SPTBN4,DYNLL1,NTRK3,PPM1E,CHD9,CAMTA1,SZT2" MicroRNA hsa-miR-1322:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 9 53 "ATP1B3,PPP1R16B,GOLGA7,TUBA1B,MMADHC,KANSL1,C1orf109,ALG1,KCNK12" MicroRNA hsa-miR-3682-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 9 53 "ZBTB10,ATP1B3,SRSF11,ZSCAN23,FEM1B,MRVI1,PRRC2B,HMGCR,LAT2" MicroRNA hsa-miR-4427:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 9 53 "UBXN2A,ERBB2,RASSF8,ZNF491,N6AMT1,PEX2,MCMBP,FNBP1,SMUG1" MicroRNA hsa-miR-301b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 10 65 "NDRG2,ERBB2,SYTL4,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ARL10,ZNF708" MicroRNA hsa-miR-8080:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 6.25E-01 1.39E-04 1.28E-03 10 65 "TEX22,AK2,MYRF,BAG4,SEC23B,GCK,GSN,IQSEC3,PRRT2,NACC2" MicroRNA hsa-miR-139-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-04 6.34E-01 1.41E-04 1.30E-03 13 105 "TEX22,TMEM170A,DNAL1,TUBD1,SLC43A2,ZNF585B,ZNF589,NFIX,SMIM7,PKIA,SETD5,USP22,SSBP2" MicroRNA hsa-miR-6069:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-04 6.48E-01 1.44E-04 1.33E-03 8 42 "LDHD,CRY2,EBI3,FGF1,FOXO3,FAM107A,MRAS,INTS3" MicroRNA hsa-miR-6085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-04 6.48E-01 1.44E-04 1.33E-03 11 78 "METTL6,TMEM184B,NCOR2,STAMBP,PRRC2B,KCNH2,PKD1,PKM,KCTD15,MTRF1L,INTS3" MicroRNA hsa-miR-3943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-04 6.48E-01 1.44E-04 1.33E-03 11 78 "TEX22,HCN2,KIF26A,MUM1,METTL21A,STMN1,NEXMIF,NSD1,RPL7L1,TOM1L2,GDPD5" MicroRNA hsa-miR-191-5p:Functional MTI Functional MTI miRTarbase 1.16E-04 6.48E-01 1.44E-04 1.33E-03 11 78 "USP37,SPATA2,GOLGA7,EMX2,MTSS1L,ACSS1,TJAP1,HNRNPM,DCUN1D2,SATB1,LRRC8A" MicroRNA hsa-miR-4732-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-04 6.48E-01 1.44E-04 1.33E-03 11 78 "RNF157,SEC14L5,ST6GALNAC3,LAYN,KSR2,ZIK1,PRIMA1,ALG1,DOK6,TUBB2A,ZNF138" MicroRNA hsa-miR-1908-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-04 6.81E-01 1.52E-04 1.40E-03 15 135 "PTCHD1,PDZD4,PRX,ARHGDIA,EVI5L,ZNF385A,MYADM,MTSS1L,C12orf49,PTGR2,SBF1,PEX26,WBP2,VGF,ZNF154" MicroRNA hsa-miR-3173-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-04 6.81E-01 1.52E-04 1.40E-03 15 135 "XKR4,SORCS2,ZNF578,TRMT9B,CDC14B,LIN54,CHRDL1,NOVA2,TMEM231,ASTN2,NACC2,ASXL3,BCL2L13,WRN,ITM2C" MicroRNA hsa-miR-541-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-04 6.88E-01 1.53E-04 1.41E-03 17 166 "ELMSAN1,APH1A,ERBB2,ANKFY1,CRCP,GLI2,METTL21A,ZC3H12B,NFIX,GPR173,FXYD1,TRIM67,SPART,CLASP1,CRTC1,RICTOR,ITM2C" MicroRNA hsa-miR-4786-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-04 6.88E-01 1.53E-04 1.41E-03 23 266 "SMIM17,DOCK11,CCNT1,NRXN3,CTH,USP6NL,YTHDC1,MRO,SCARA3,AFF2,KIAA1841,LUZP2,MMP17,SFR1,ZDHHC8,CCSER2,BDNF-AS,PEX2,CEP97,KLHL11,PEX26,SLC37A2,TBC1D15" MicroRNA hsa-miR-210:PITA hsa-miR-210:PITA_TOP PITA 1.24E-04 6.92E-01 1.54E-04 1.42E-03 7 32 "ELFN2,SEMA6A,RCAN2,NPTX1,ZNF827,SEMA5B,CAMTA1" MicroRNA hsa-miR-1281:mirSVR_highEffct hsa-miR-1281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-04 6.95E-01 1.55E-04 1.42E-03 12 92 "ASPHD1,LDB2,SEC24C,DNM1L,SYNCRIP,FAM216A,PTPRD,HSD11B1L,SPTB,AMACR,DCBLD1,UPF3A" MicroRNA hsa-miR-4519:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-04 6.95E-01 1.55E-04 1.42E-03 12 92 "ELFN2,CASK,CSNK1E,OSBPL3,SOCS5,IP6K1,FEM1B,CHIC1,ZNF680,BDNF-AS,ZC3H14,ATXN2" MicroRNA hsa-miR-1285-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-04 7.13E-01 1.58E-04 1.46E-03 10 66 "INTS2,RCAN1,ASB3,SEC23B,SHC3,TMLHE,AGTPBP1,OSBP2,CCDC14,ZDHHC20" MicroRNA hsa-miR-33b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-04 7.26E-01 1.61E-04 1.48E-03 9 54 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,FLT1,AFF1,ADAM22,ZC3H12B" MicroRNA "GTAAGAT,MIR-200A:MSigDB" "GTAAGAT,MIR-200A:MSigDB" MSigDB 1.30E-04 7.26E-01 1.61E-04 1.48E-03 9 54 "QKI,IPCEF1,DLC1,FGF13,NOVA1,PAX6,SGK1,UBE3A,GAN" MicroRNA hsa-miR-3677-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-04 7.26E-01 1.61E-04 1.48E-03 9 54 "TAOK1,IP6K1,CELF1,GATM,MAPT,SMOX,KANK1,ZC3H4,FBXO36" MicroRNA hsa-miR-320d:Functional MTI Functional MTI miRTarbase 1.30E-04 7.29E-01 1.62E-04 1.49E-03 11 79 "ADD1,SEMA7A,TNRC6C,C2CD2,SYNCRIP,SRCAP,RBPJ,HSPA4L,TAL1,ARL10,SLC38A1" MicroRNA hsa-miR-5584-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-04 7.29E-01 1.62E-04 1.49E-03 11 79 "C1orf52,SUSD5,UBXN2A,MTX3,AFF2,MTHFD2,FUT10,LSAMP,PNMA3,MYO18A,TNS1" MicroRNA hsa-miR-3198:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-04 7.35E-01 1.63E-04 1.50E-03 14 121 "SEMA7A,DNAL1,DNAJB6,CAMKK2,GLUL,ZNF426,ELP2,SCN2B,HSPA4L,NUBPL,FAM126B,CDK19,KIAA0930,ZNF708" MicroRNA hsa-miR-7150:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-04 7.40E-01 1.64E-04 1.51E-03 15 136 "LONRF2,ZMYM4,PITPNM3,CD99L2,TUBD1,APOPT1,MALT1,TNRC6A,FUT10,DDX19B,NFIX,PDE3A,MYH15,SATB2,DPYSL5" MicroRNA hsa-miR-187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.49E-01 1.66E-04 1.53E-03 6 23 "CCPG1,CRMP1,HIPK3,MRO,MAD2L2,INPP5B" MicroRNA hsa-miR-2909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.71E-01 1.71E-04 1.57E-03 8 43 "TXNDC16,APPL1,RASA4,UBE2QL1,SH3TC2,ZMAT4,NFASC,NEK4" MicroRNA hsa-miR-4803:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.72E-01 1.71E-04 1.58E-03 12 93 "EPS15L1,BAG4,SV2B,EFHB,PRKAB2,MAPK7,SLC25A36,SGK1,SS18,TUBB2A,UBE2H,ZNF711" MicroRNA hsa-miR-2115-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.72E-01 1.71E-04 1.58E-03 12 93 "ARRB2,ZNF445,FAM13A,FKTN,APOPT1,LILRA2,ZNF496,SHISAL1,NCOA7,PSAT1,SGK1,NSD1" MicroRNA hsa-miR-194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.72E-01 1.71E-04 1.58E-03 12 93 "AQP6,CDH2,DNAL1,EIF4G2,SRCAP,HNF4G,TJAP1,ZC3H12B,PTPN13,SETD5,PEX26,FXR1" MicroRNA hsa-miR-100-5p:Functional MTI Functional MTI miRTarbase 1.40E-04 7.85E-01 1.74E-04 1.60E-03 22 251 "ATP1B3,ATP2A2,QKI,NCOR2,YTHDC1,HS3ST2,MED12,FARSB,FGFR3,UBE2E3,FLT1,CAMKK2,MAP4,MKLN1,RPL15,ATAT1,KANK1,PRRC2C,DCBLD1,RPL7L1,USP1,NLRP3" MicroRNA hsa-miR-3116:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-04 8.03E-01 1.78E-04 1.64E-03 14 122 "CLK4,HECW2,APBB2,CDC14B,KLHL3,PHC2,ERBB2,ANKMY1,PCYOX1,NXPH3,C2orf72,PKM,ANKRD24,PARD3" MicroRNA hsa-miR-6081:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-04 8.03E-01 1.78E-04 1.64E-03 14 122 "CASKIN1,AK2,ENTPD4,IST1,E2F6,HEYL,PRRC2B,KIF5A,KCNIP3,HIF3A,NACC2,RPRM,TMEM63C,GAN" MicroRNA hsa-miR-7156-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-04 8.04E-01 1.78E-04 1.64E-03 15 137 "SEMA6A,PHF12,DST,CSNK1G3,ZBTB24,C8orf37,TMEM132C,IL6R,IBA57,ZNF680,GPR137C,CPEB3,BDP1,MPRIP,UBE2H" MicroRNA hsa-miR-10a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-04 8.11E-01 1.80E-04 1.65E-03 10 67 "CDR1,DBN1,IRAK4,RGS17,IGF1,RCOR3,NR2C2,UBE2H,ZNF24,ZBTB38" MicroRNA hsa-miR-551a:mirSVR_highEffct hsa-miR-551a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.46E-04 8.17E-01 1.81E-04 1.67E-03 11 80 "SLC25A14,RAB33A,LETMD1,NTRK2,PTK2,TMEM255A,NCBP3,NUBPL,PJA1,CRB2,JPH3" MicroRNA hsa-miR-3975:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-04 8.17E-01 1.81E-04 1.67E-03 11 80 "SLC24A4,CEP126,ARHGDIA,CCNT1,ZNF385A,CRY2,RIMS4,KIAA0408,PRRC2B,DDN,URM1" MicroRNA hsa-miR-3137:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "RASL11B,AKAP12,SOCS5,FAM131B,DNAJB6,ZIC5,IL6ST,NPTX2,KSR2" MicroRNA hsa-miR-135b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "EVI5L,TOGARAM2,KCND1,NPTX2,GPR137C,SETD5,ZNF423,THRA,ZNF138" MicroRNA hsa-miR-885-3p:PITA hsa-miR-885-3p:PITA_TOP PITA 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "DOC2A,MARK4,RIMS4,IP6K1,L1CAM,ZNF827,SMPD3,ST5,TNS1" MicroRNA hsa-miR-3972:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "SFMBT2,LDLRAD4,CBS,TMEM184B,BAG4,KIAA1958,PIK3R1,ZBTB43,ZNF28" MicroRNA hsa-miR-767-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "CACNA1A,FBXL5,RCAN1,HIPK3,GSN,PPM1L,MMP16,GPRIN3,VLDLR" MicroRNA hsa-miR-582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "AXIN2,NFS1,ENTPD4,FER,MPP2,WBP1L,LRRK2,ARL10,GAN" MicroRNA hsa-miR-6772-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 8.40E-01 1.86E-04 1.71E-03 9 55 "RNF157,TBC1D14,NCOA1,CSNK1E,AMOTL2,SRRM4,POLL,MN1,PRRC2C" MicroRNA hsa-miR-3674:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-04 8.46E-01 1.87E-04 1.72E-03 13 108 "RNF157,ARNTL,BAG4,TOGARAM2,SEC14L5,IP6K1,MTX3,SLC2A6,LAYN,GPR137C,BTBD3,PUM2,ZNF138" MicroRNA hsa-miR-320c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-04 8.46E-01 1.87E-04 1.72E-03 13 108 "ADD1,SEMA7A,TNRC6C,C2CD2,SCRN1,SYNCRIP,SRCAP,RBPJ,SEC14L1,HSPA4L,TAL1,PCDHA2,ARL10" MicroRNA hsa-miR-7702:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-04 8.51E-01 1.88E-04 1.73E-03 7 33 "ELMSAN1,PTPRT,RXRA,ELOVL4,STXBP4,ZBTB38,FXR1" MicroRNA hsa-miR-8058:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-04 8.51E-01 1.88E-04 1.73E-03 7 33 "LRWD1,E2F6,HIPK3,RNF165,FITM2,MYO18A,SLC30A4" MicroRNA hsa-miR-8087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-04 8.56E-01 1.89E-04 1.74E-03 12 94 "LDHD,CNTNAP2,STARD3NL,TLR7,CELF1,PACSIN2,KPNA5,TCP11L1,PEX26,TSC1,ZNF138,ZBTB38" MicroRNA hsa-miR-3191-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-04 8.56E-01 1.89E-04 1.74E-03 12 94 "RNF157,RASSF2,C2CD2L,EDN3,SYTL4,P2RX7,PDE3A,PDE1B,PDPK1,ZFP1,ZNF415,SSBP2" MicroRNA hsa-miR-8052:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.72E-01 1.92E-04 1.77E-03 15 138 "ESYT2,ATP1B3,ZMYM4,CBARP,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,TDRKH,KCNK3,ARHGAP26,LAT2,CFAP298" MicroRNA hsa-miR-3199:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.72E-01 1.92E-04 1.77E-03 15 138 "ESYT2,ATP1B3,ZMYM4,CBARP,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,TDRKH,KCNK3,ARHGAP26,LAT2,CFAP298" MicroRNA hsa-miR-4278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-04 9.12E-01 2.01E-04 1.85E-03 8 44 "MTA3,EVI5L,PKD1,SETD5,SHMT2,NMNAT2,ERC1,THRA" MicroRNA hsa-miR-369-5p:mirSVR_highEffct hsa-miR-369-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "UPRT,DIS3L,FAM171B,ABCG1,ARHGAP24,YTHDC1,DTNB,FAM198B,ATP2C1,WBP1L,FAM155A" MicroRNA hsa-miR-433-3p:Functional MTI Functional MTI miRTarbase 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "BBS2,LONRF2,ENTPD4,EDN1,PLEKHA1,MBNL1,CHD9,NUBPL,FAM126B,ERBIN,KLHL4" MicroRNA hsa-miR-127-3p:mirSVR_highEffct hsa-miR-127-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "SYN3,SEPT7,GDA,EPHB1,AGAP3,AP4B1,ZNF496,MAPK4,BCAS3,SCN8A,P2RY12" MicroRNA hsa-miR-4433b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "MTUS1,CA12,PITPNM3,SYNPO,RDX,MAP6D1,GALNT10,SZT2,WBP2,VLDLR,ZNF24" MicroRNA hsa-miR-1226-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "ELFN2,OGT,ARHGEF2,CBARP,ABCC5,CHST15,GSN,MMP17,SLC2A5,SEPT8,CBX5" MicroRNA hsa-miR-103a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-04 9.15E-01 2.02E-04 1.86E-03 11 81 "GPR146,MTMR7,ZNF585B,PTPRT,IDH3B,LIFR,LSAMP,PDE3A,MTRF1L,CYB561D1,SNAP25" MicroRNA hsa-miR-3139:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.20E-01 2.03E-04 1.86E-03 10 68 "PCYOX1,AHDC1,PRRC2B,RNF165,KCNH2,KLHL11,MYH15,IQSEC2,THRA,TUBB2A" MicroRNA hsa-miR-4313:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.20E-01 2.03E-04 1.86E-03 10 68 "LRFN1,HCN2,NCOR2,MUM1,ITPKB,XRRA1,PDE4A,ZDHHC8,PIGG,TOM1L2" MicroRNA hsa-miR-301a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.20E-01 2.03E-04 1.86E-03 10 68 "NDRG2,ERBB2,SYTL4,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ARL10,ZNF708" MicroRNA hsa-miR-4753-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-04 9.29E-01 2.04E-04 1.88E-03 13 109 "ADCY5,CRY2,LRIG1,EIF5,SLC35G1,KCNN3,OCRL,SDK2,SLC25A36,R3HDM2,INAVA,NSD1,NETO2" MicroRNA hsa-miR-548g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-04 9.48E-01 2.09E-04 1.92E-03 12 95 "BAG4,E2F6,STARD3NL,SCML2,SUCO,PACSIN2,ELOVL5,MXI1,KANSL1,TLR4,ZFAND5,NHSL1" MicroRNA hsa-miR-2278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-04 9.55E-01 2.10E-04 1.93E-03 14 124 "AXIN2,FZD9,DNAH17,ZBTB10,ARHGAP32,DLC1,ATOH8,SHISA6,MSL1,MN1,RNH1,EPN2,ANKRD36,UBE2H" MicroRNA hsa-miR-3621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.68E-01 2.13E-04 1.96E-03 6 24 "LTBP4,KCNK3,KCNN1,CAMK2N2,SEPT4,ADAMTS17" MicroRNA hsa-miR-887:PITA hsa-miR-887:PITA_TOP PITA 1.73E-04 9.68E-01 2.13E-04 1.96E-03 6 24 "RNF150,ATP2B2,CCPG1,NPTX1,SAFB,SCN8A" MicroRNA hsa-miR-3178:mirSVR_highEffct hsa-miR-3178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-04 9.68E-01 2.13E-04 1.96E-03 6 24 "NRN1,TUBB3,STAU2,CELF5,CDK18,KCNE5" MicroRNA hsa-miR-639:PITA hsa-miR-639:PITA_TOP PITA 1.73E-04 9.68E-01 2.13E-04 1.96E-03 6 24 "LYPD1,AGAP2,KCND1,LSS,MSI1,KANSL1" MicroRNA hsa-miR-4676-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.69E-01 2.13E-04 1.96E-03 9 56 "BEND6,HACE1,TXNDC16,HEYL,DOT1L,SEMA6D,TMCC1,ZNF621,CLASP1" MicroRNA hsa-miR-5581-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.69E-01 2.13E-04 1.96E-03 9 56 "SEPT7,SIPA1L1,DNAJB6,HAS2,NKD1,ADAM22,ZDHHC14,MSANTD2,NSD1" MicroRNA hsa-miR-96-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.69E-01 2.13E-04 1.96E-03 9 56 "FMNL2,BACH1,TBPL1,NRG2,SYNCRIP,SMC2,ZNF678,OLA1,PGBD4" MicroRNA hsa-miR-6888-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-04 9.80E-01 2.15E-04 1.98E-03 16 155 "SMIM17,PDZD4,TTLL9,TOGARAM2,GAPVD1,PDE4D,CEP97,SH3TC2,HSD11B1L,HES6,SLC8A1,MYH15,MCF2L2,SLC19A3,BHLHB9,SSBP2" MicroRNA hsa-miR-6875-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-04 1.00E+00 2.24E-04 2.06E-03 13 110 "ELFN2,ZNF385A,ENTPD4,EIF4G1,MTSS1L,GSN,NCR3LG1,MORC4,MYO18A,CAMTA2,NACC2,TPM2,TUBB2A" MicroRNA hsa-miR-3126-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-04 1.00E+00 2.24E-04 2.06E-03 13 110 "ELFN2,ZNF385A,ENTPD4,EIF4G1,MTSS1L,GSN,NCR3LG1,MORC4,MYO18A,CAMTA2,NACC2,TPM2,TUBB2A" MicroRNA hsa-miR-4769-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-04 1.00E+00 2.24E-04 2.07E-03 11 82 "ARSE,QKI,BOC,EDN1,EDN3,EPB41,CELF1,ZNF546,PLCL1,RXRA,ZNF106" MicroRNA hsa-miR-1298:PITA hsa-miR-1298:PITA_TOP PITA 1.86E-04 1.00E+00 2.28E-04 2.10E-03 7 34 "ATP2B2,BMP7,BAG4,PDCD6IP,TTBK1,MXI1,TRPS1" MicroRNA hsa-miR-542-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 7 34 "ZNF385A,SEC16A,GRIN3A,EGFR,EMID1,MPRIP,SH3GLB2" MicroRNA hsa-miR-3654:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 7 34 "ESYT2,TMEM184B,HIPK3,SAMD5,KSR2,MSANTD2,GPRIN3" MicroRNA hsa-miR-4740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 14 125 "AS3MT,RNF157,ESYT2,PTBP2,HINFP,KIAA0408,DNAL1,TUBD1,FDFT1,PCYOX1,KIAA1958,EID2B,CFAP298,GAN" MicroRNA hsa-miR-566:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 10 69 "SLC24A4,TXNDC16,DOCK11,RNF14,METTL21A,CHST6,CBX5,LAT2,CFAP298,GAN" MicroRNA hsa-miR-3974:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 10 69 "ABCF1,TXNDC16,SRSF11,CRY2,CRCP,NXPH3,MAP2,ZNF713,KANSL1,HUNK" MicroRNA hsa-miR-6882-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 10 69 "DST,TMEM170A,KLHL3,MRVI1,FER,SEPT9,MAP4,NFIX,KCTD15,NCBP3" MicroRNA hsa-miR-3606-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 10 69 "CBR1,BAG4,DCTN4,OCRL,KANSL1,ROBO1,KIF27,TRA2B,SLC6A8,ZDHHC20" MicroRNA hsa-miR-513b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-04 1.00E+00 2.28E-04 2.10E-03 10 69 "PHF12,ATP1B3,ARHGEF4,DPP6,RCAN2,PTPRB,NSD1,WBP2,TOM1L2,JMJD1C" MicroRNA hsa-miR-181c*:mirSVR_highEffct hsa-miR-181c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-04 1.00E+00 2.29E-04 2.11E-03 12 96 "THSD7A,CFL2,LRRC3B,EMX2,PPARGC1A,LIG4,SMAD1,RTL5,SCN7A,PPP4R3A,OSBP2,RICTOR" MicroRNA hsa-miR-3126-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-04 1.00E+00 2.35E-04 2.16E-03 8 45 "DBT,MAT2A,PPP1R1A,PTPRE,DPF2,PEX26,SLC6A8,TMPO" MicroRNA hsa-miR-6767-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-04 1.00E+00 2.35E-04 2.16E-03 8 45 "DNAL1,MPP2,HS6ST3,GPR173,STX1B,WDR37,RPL7L1,ELFN1" MicroRNA hsa-miR-555:PITA hsa-miR-555:PITA_TOP PITA 1.99E-04 1.00E+00 2.44E-04 2.24E-03 9 57 "MAP4K4,NCOR2,PAN3,FOXO3,IPO5,FA2H,SATB2,FRYL,TPM1" MicroRNA hsa-miR-126-3p:Functional MTI Functional MTI miRTarbase 1.99E-04 1.00E+00 2.44E-04 2.24E-03 9 57 "PITPNC1,TOM1,FOXO3,PIK3R1,RGS3,TCF4,TEK,SIRT1,EVI5" MicroRNA hsa-miR-892c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-04 1.00E+00 2.44E-04 2.24E-03 9 57 "BEND6,HACE1,TXNDC16,HEYL,DOT1L,SEMA6D,TMCC1,ZNF621,CLASP1" MicroRNA hsa-miR-6823-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-04 1.00E+00 2.44E-04 2.25E-03 13 111 "ARSE,DLC1,TNRC6A,ZHX1,PPM1L,MINDY2,FBXW7,RMI1,GALNT10,MAPKBP1,PCDHA6,ZNF74,ITM2C" MicroRNA hsa-miR-6803-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-04 1.00E+00 2.44E-04 2.25E-03 13 111 "ARHGDIA,BCL7A,ZNF385A,DBT,DOT1L,NLE1,DIRAS2,HSD11B1L,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1" MicroRNA hsa-miR-564:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-04 1.00E+00 2.44E-04 2.25E-03 13 111 "XKR4,APAF1,LONRF2,APPL1,SLC43A2,GPR75,GPR155,GPSM2,SMOX,STRN3,ANKRD36,SSTR2,SS18" MicroRNA hsa-miR-3130-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-04 1.00E+00 2.49E-04 2.29E-03 11 83 "WDR35,AK2,DST,CRY2,SV2B,FUT9,DDX19B,ZNF491,GPR137C,ZHX3,LHPP" MicroRNA hsa-miR-6895-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-04 1.00E+00 2.49E-04 2.29E-03 11 83 "TXNDC16,C6orf89,PRX,RGS6,APPL1,POLR1B,TMEM231,SH3BP2,R3HDM2,ANKRD24,ITM2C" MicroRNA hsa-miR-4437:Functional MTI Functional MTI miRTarbase 2.04E-04 1.00E+00 2.49E-04 2.29E-03 11 83 "CPNE5,ARHGDIA,RIPOR2,RUSC2,AMOTL2,NEGR1,ITPKB,HKR1,SETD5,SLC6A8,BDP1" MicroRNA hsa-miR-6126:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-04 1.00E+00 2.57E-04 2.36E-03 10 70 "TMCC3,ARRB1,AKAP5,IRAK3,LIFR,CLDN11,PMP22,MAPKBP1,SATB2,ZNF74" MicroRNA hsa-miR-5000-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-04 1.00E+00 2.57E-04 2.36E-03 10 70 "KALRN,C1orf52,PREPL,ANKRD46,EIF5,TCERG1,TNRC6A,PRRC2B,ZNF678,BTBD3" MicroRNA hsa-miR-1185-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-04 1.00E+00 2.57E-04 2.36E-03 10 70 "GAPVD1,SYNCRIP,KCNMB4,MAT2A,NUCB2,ZNF426,C1orf109,MRAS,HSPA4L,TPM1" MicroRNA hsa-miR-4422:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-04 1.00E+00 2.66E-04 2.45E-03 13 112 "MTA3,KIAA0408,DCAF8,ELOVL5,NEGR1,BLOC1S2,PDE4D,PDPK1,SDK2,SNRK,KLHL11,SEC31A,HECW1" MicroRNA hsa-miR-185-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-04 1.00E+00 2.66E-04 2.45E-03 13 112 "USP37,RGS6,ABCC5,PRRC2B,PKM,KIAA0895L,SBF1,SCN2B,PEX26,THRA,WBP2,INTS3,TMEM63C" MicroRNA hsa-miR-383-5p:Functional MTI Functional MTI miRTarbase 2.18E-04 1.00E+00 2.66E-04 2.45E-03 13 112 "ANKRD44,MRNIP,SUCO,SMC2,GLUL,ZIC5,SLC11A2,SH3TC2,PEAR1,WBP2,TSN,ZFP37,GDPD5" MicroRNA hsa-miR-5739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-04 1.00E+00 2.69E-04 2.48E-03 6 25 "CACNA1B,SCARB1,EPS15L1,TNRC6A,CHIC1,GPR173" MicroRNA hsa-miR-6753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 2.74E-04 2.52E-03 7 35 "KLHL3,RPS6KL1,CYP27C1,KSR2,PALM,PKIA,ZMAT4" MicroRNA hsa-miR-7152-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 2.74E-04 2.52E-03 7 35 "TMEM184B,IP6K1,RPS6KL1,FEM1B,ZNF461,SEPT4,THRA" MicroRNA hsa-miR-342-5p:PITA hsa-miR-342-5p:PITA_TOP PITA 2.25E-04 1.00E+00 2.74E-04 2.53E-03 8 46 "PDZD4,CCAR2,SNAP91,PPARGC1A,NFIX,TMEM255A,CPEB3,FAM214B" MicroRNA hsa-miR-99b:mirSVR_highEffct hsa-miR-99b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.25E-04 1.00E+00 2.74E-04 2.53E-03 8 46 "CYBB,SLC29A4,FGFR3,TUBGCP4,MIER3,MBNL1,PRRC2C,SLC44A1" MicroRNA hsa-miR-3158-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 2.74E-04 2.53E-03 8 46 "BCL7A,CABP7,THSD7A,CHST15,AMOTL2,MRPS18A,NLGN1,NFASC" MicroRNA hsa-miR-4446-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-04 1.00E+00 2.76E-04 2.55E-03 11 84 "CABP7,DRP2,AMOTL2,CELF1,PRRC2B,KCNH2,MAP4,PLCD1,NLGN1,PEX26,NFASC" MicroRNA hsa-miR-376b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.27E-04 1.00E+00 2.76E-04 2.55E-03 11 84 "MYRF,RIMS2,YAF2,AMOTL2,CYP27C1,SHC3,ZNF426,ZNF844,ZNF667,SLC35G2,ZNF781" MicroRNA hsa-miR-4664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-04 1.00E+00 2.78E-04 2.56E-03 12 98 "CRLF1,ZNF385A,IP6K1,ELN,GLI2,PRRC2B,MPP2,MAPK10,KLHDC8A,ATXN2,NMNAT2,UBTF" MicroRNA hsa-miR-4536-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-04 1.00E+00 2.78E-04 2.56E-03 9 58 "FMNL2,OSBPL8,UBXN2A,ZC3H11A,TENM1,DDX19B,MTRF1L,PRRC2C,ITGB3BP" MicroRNA hsa-miR-1228*:mirSVR_highEffct hsa-miR-1228*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-04 1.00E+00 2.88E-04 2.65E-03 10 71 "AP2A2,AGT,CACNA1B,DDR1,SEZ6L2,CLEC18A,CNNM2,CASTOR1,SLC11A1,KLC2" MicroRNA hsa-miR-299-3p:Functional MTI Functional MTI miRTarbase 2.37E-04 1.00E+00 2.88E-04 2.65E-03 10 71 "DNAL1,E2F6,NEGR1,IGF1,MYCN,PMP22,ATXN2,PEG10,ITGB3BP,BCL2L13" MicroRNA hsa-miR-365a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-04 1.00E+00 2.90E-04 2.67E-03 14 128 "ESYT2,ATP1B3,ENTPD6,ZMYM4,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,KCNK3,ARHGAP26,LAT2,CFAP298" MicroRNA hsa-miR-4328:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-04 1.00E+00 2.90E-04 2.67E-03 14 128 "LONRF1,EDIL3,EDN1,EIF1,RACK1,FOXO3,IL6ST,PDE3A,PLCL1,FBXW7,CPEB3,NMNAT2,MPRIP,PPIL6" MicroRNA hsa-miR-5685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-04 1.00E+00 3.05E-04 2.81E-03 12 99 "KALRN,CS,HEYL,EBI3,LYVE1,NCKAP1L,METTL21A,MMP17,VWA2,ZDHHC8,PRRT2,KIAA0930" MicroRNA hsa-miR-1276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 3.07E-04 2.82E-03 16 160 "INTS2,CALM1,SLC16A4,AKAP6,CHRDL1,DPP6,STARD3NL,TUBD1,TRMO,SARAF,PTPRT,LAMP2,MAT2A,GPR137C,PDZRN4,TBL1X" MicroRNA hsa-miR-6516-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 3.07E-04 2.82E-03 11 85 "ABCF1,ATP1B3,BACH1,CACNA1A,TOGARAM2,NRG2,TENM1,C8orf37,MED12L,GPR137C,MKRN3" MicroRNA hsa-miR-6842-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 3.07E-04 2.82E-03 11 85 "ARHGDIA,CACNA1A,C1orf52,SV2B,MRVI1,CELF1,ADAP1,IBA57,MMP17,PEX2,ZNF24" MicroRNA hsa-miR-1244:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.61E-04 1.00E+00 3.17E-04 2.92E-03 9 59 "TAOK1,CDH2,LIN54,DNAL1,TMEM35A,RDX,ATF7IP,TRIM2,ZFP37" MicroRNA hsa-miR-4460:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.63E-04 1.00E+00 3.19E-04 2.94E-03 8 47 "DST,ZC3H11A,GATM,RAB30,SMOX,CNKSR2,ZNF621,ZXDA" MicroRNA hsa-miR-3613-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.63E-04 1.00E+00 3.19E-04 2.94E-03 8 47 "XKR4,MTX3,VPS13B,KATNAL1,SARAF,NTNG2,NCR3LG1,NHSL1" MicroRNA hsa-miR-3692-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "BAG4,DCAF8,SV2B,FER,ZBED3,FICD,ADAM22,MYCN,C12orf49,NCBP3" MicroRNA hsa-miR-6750-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "PHF12,LDHD,TM9SF4,GTF2IRD2,CAMKK2,NPTX1,NPTX2,SLC25A36,TUBB2A,MPPE1" MicroRNA hsa-miR-3191-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "HCN2,TPP1,TBPL1,SEPT9,GCK,SESN1,PKM,POLR2F,SBF1,SIN3B" MicroRNA hsa-miR-4453:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "SORCS2,CALM1,CBS,EPB41,PDLIM5,FAM98B,PGBD4,FBXO11,TUBB2A,XPO1" MicroRNA hsa-miR-6822-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "PHF12,LDHD,TM9SF4,GTF2IRD2,CAMKK2,NPTX1,NPTX2,SLC25A36,TUBB2A,MPPE1" MicroRNA hsa-miR-1265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "TAOK1,WDPCP,ANKRD46,KIF5A,GPR137C,PDE3A,PPP2R5E,SETD5,MRAS,TUBB2A" MicroRNA hsa-miR-4538:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-04 1.00E+00 3.23E-04 2.97E-03 10 72 "SORCS2,CALM1,CBS,EPB41,PDLIM5,FAM98B,PGBD4,FBXO11,TUBB2A,XPO1" MicroRNA "AGCGCTT,MIR-518F:MSigDB" "AGCGCTT,MIR-518F:MSigDB" MSigDB 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "ZNF608,CAPN3,ZNF385A,EGR3,MCF2L" MicroRNA "AGCGCTT,MIR-518A:MSigDB" "AGCGCTT,MIR-518A:MSigDB" MSigDB 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "ZNF608,CAPN3,ZNF385A,EGR3,MCF2L" MicroRNA hsa-miR-450a:PITA hsa-miR-450a:PITA_TOP PITA 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "ZNF608,KMT5B,MEIS1,MEIS2,KANSL1" MicroRNA "AGCGCTT,MIR-518E:MSigDB" "AGCGCTT,MIR-518E:MSigDB" MSigDB 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "ZNF608,CAPN3,ZNF385A,EGR3,MCF2L" MicroRNA hsa-miR-1247:PITA hsa-miR-1247:PITA_TOP PITA 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "TAOK3,BRSK1,TNRC6A,MYCBP2,POLR3H" MicroRNA hsa-miR-614:PITA hsa-miR-614:PITA_TOP PITA 2.68E-04 1.00E+00 3.25E-04 2.99E-03 5 17 "GAS7,NRG2,CPEB4,PLCB1,TCF4" MicroRNA hsa-miR-126-3p.2:TargetScan hsa-miR-126-3p.2 TargetScan 2.78E-04 1.00E+00 3.37E-04 3.10E-03 6 26 "ANKRD44,PLXNA4,PDE4A,PIK3R1,CPEB4,ADAMTS9" MicroRNA hsa-miR-6078:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-04 1.00E+00 3.37E-04 3.10E-03 6 26 "ZNF638,LUZP2,ATOH8,METTL21A,CYP27C1,TMEM198" MicroRNA hsa-miR-375:PITA hsa-miR-375:PITA_TOP PITA 2.78E-04 1.00E+00 3.37E-04 3.10E-03 6 26 "PLEKHH1,DPYSL2,SYNCRIP,NFIX,WBP1L,ROBO2" MicroRNA hsa-miR-1273a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-04 1.00E+00 3.39E-04 3.12E-03 11 86 "NRXN3,ANKFY1,FUT9,KCNN3,CHST6,ZSCAN2,ALG9,FNBP1,ARL10,PPIL6,UBC" MicroRNA hsa-miR-4676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-04 1.00E+00 3.39E-04 3.13E-03 14 130 "ATP2A2,UBXN2A,DBN1,RACK1,TRAF3IP2,CRCP,CHST6,MKLN1,ZNF680,POLR2F,NCBP3,USP1,DHX33,MSRB3" MicroRNA hsa-miR-575:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-04 1.00E+00 3.39E-04 3.13E-03 14 130 "ATP2A2,UBXN2A,DBN1,RACK1,TRAF3IP2,CRCP,CHST6,MKLN1,ZNF680,POLR2F,NCBP3,USP1,DHX33,MSRB3" MicroRNA hsa-miR-6510-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-04 1.00E+00 3.44E-04 3.16E-03 13 115 "ARHGDIA,LDLRAD4,ABCC5,DCTN4,FAM49B,KCTD15,SALL1,ERC1,ZC3H4,ASXL3,WBP2,BCL2L13,ITM2C" MicroRNA hsa-miR-145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.97E-04 1.00E+00 3.59E-04 3.31E-03 9 60 "TMCC2,C8orf37,POLL,MMP16,NTRK2,TRA2B,CLSTN2,TPM1,JMJD1C" MicroRNA hsa-miR-4657:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-04 1.00E+00 3.61E-04 3.32E-03 10 73 "CA8,LRWD1,SRSF11,CRCP,MYCN,GPR137C,PEG10,ATMIN,ITGB3BP,BCL2L13" MicroRNA hsa-miR-4491:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-04 1.00E+00 3.61E-04 3.32E-03 10 73 "CA8,LRWD1,SRSF11,CRCP,MYCN,GPR137C,PEG10,ATMIN,ITGB3BP,BCL2L13" MicroRNA hsa-miR-1247:mirSVR_highEffct hsa-miR-1247:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.98E-04 1.00E+00 3.61E-04 3.32E-03 10 73 "ADAM15,CS,WDR83,CLASRP,IRAK3,HP,NPTX2,SEMA6D,SOX15,MYCBP2" MicroRNA hsa-miR-1306:mirSVR_highEffct hsa-miR-1306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.03E-04 1.00E+00 3.66E-04 3.37E-03 12 101 "AIF1L,FAM198B,SMC2,MSTN,BRD8,IDH3B,PCSK5,CEP41,SLA,ADGRL3,TPCN2,TIAM1" MicroRNA hsa-miR-1205:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-04 1.00E+00 3.66E-04 3.37E-03 12 101 "STX16,DLC1,ATOH8,KCNH2,MSI1,ENPP2,PKM,MTRF1L,HES6,CLASP1,UBE2H,GDPD5" MicroRNA hsa-miR-553:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-04 1.00E+00 3.67E-04 3.38E-03 4 10 "DST,EMX2,TBC1D16,LSAMP" MicroRNA hsa-miR-4687-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-04 1.00E+00 3.69E-04 3.39E-03 8 48 "CACNA1A,C1orf52,NDST3,AKAP6,ADAP1,ZNF793,KCNIP3,FNBP1" MicroRNA hsa-miR-146a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-04 1.00E+00 3.74E-04 3.44E-03 13 116 "ERBB2,ZNF391,ZNF678,P2RX7,PRKAB2,SH3TC2,SLC8A1,ZFP1,ZNF415,ITPRID2,ARL10,PLEKHH2,ZNF708" MicroRNA hsa-miR-613:Functional MTI Functional MTI miRTarbase 3.10E-04 1.00E+00 3.74E-04 3.44E-03 11 87 "CLCN3,RIMS4,MATR3,MYEF2,COQ7,ZBED3,STAMBP,FYB1,DDX19B,FNDC3A,WBP2" MicroRNA hsa-miR-365b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-04 1.00E+00 3.74E-04 3.44E-03 11 87 "PCDH10,AKAP12,CS,POLR1B,COMMD5,KANSL1,SNRK,CYB561D1,PCMTD2,SGK1,ZXDA" MicroRNA hsa-miR-4999-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-04 1.00E+00 3.90E-04 3.59E-03 7 37 "MARCH4,SRSF11,DNAJB6,HIPK3,ZNF589,SUCO,SOWAHA" MicroRNA hsa-miR-3927-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-04 1.00E+00 3.90E-04 3.59E-03 7 37 "SEMA7A,LONRF2,FOXO3,HSF2,LIFR,RICTOR,ZNF708" MicroRNA hsa-miR-500a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.29E-04 1.00E+00 3.96E-04 3.65E-03 14 132 "DST,FYN,SIGLEC8,MTHFD2,KIAA1958,PRRC2B,LILRA2,AGBL5,IBA57,STRN3,NWD1,KLHL11,ZBTB43,MCF2L2" MicroRNA hsa-miR-3160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.30E-04 1.00E+00 3.97E-04 3.66E-03 18 197 "ZNF578,TRMT9B,CCPG1,UBXN2A,DNAL1,EIF1,STX2,FGFR1,RNPS1,PLEC,CEP97,ALG9,FNIP1,PEX26,IQSEC2,LHPP,TUBB2A,USP1" MicroRNA hsa-miR-296-5p:Functional MTI Functional MTI miRTarbase 3.34E-04 1.00E+00 4.02E-04 3.70E-03 10 74 "SUMF2,TOGARAM2,TOM1,MTSS1L,FGFR1,ADAMTS13,ZDHHC15,NFIX,ZDHHC8,S100B" MicroRNA hsa-miR-5701:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 4.02E-04 3.70E-03 10 74 "PHF12,DDO,RUNX1T1,KLHL3,TCERG1,MAT2A,ADAM22,PDE1B,DICER1,ZNF711" MicroRNA hsa-miR-938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-04 1.00E+00 4.06E-04 3.74E-03 9 61 "ATP2A2,NUMBL,CRY2,RGS6,SOCS5,TXNL4A,FAM107A,MAPT,SNRK" MicroRNA hsa-miR-4272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-04 1.00E+00 4.13E-04 3.80E-03 11 88 "ZNF608,YTHDC1,FCF1,YAF2,PLEKHA1,TNRC6A,NEGR1,IL6ST,PLCL1,PPP2R5E,ZNF28" MicroRNA hsa-miR-4505:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-04 1.00E+00 4.17E-04 3.84E-03 17 181 "CEP126,ARHGDIA,METTL6,RGS6,MYADM,CELF1,IRAK3,IBA57,KCNH2,MMP17,PKM,PEX2,KLHDC8A,ELP2,KIAA0895L,ZNF24,TMEM63C" MicroRNA hsa-miR-4703-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-04 1.00E+00 4.25E-04 3.91E-03 8 49 "BACH1,DNAL1,ANKRD46,GORAB,GABRB3,TCERG1,AP4S1,SCP2" MicroRNA hsa-miR-3689f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-04 1.00E+00 4.25E-04 3.91E-03 8 49 "ZBED3,CELF1,ZNF181,CLIP1,CSRNP3,FAM126B,TPCN2,BCL2L13" MicroRNA hsa-miR-4320:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-04 1.00E+00 4.25E-04 3.91E-03 8 49 "TAOK1,CRY2,HLF,MPP2,UHRF1BP1L,ZNF621,CLASP1,MPPE1" MicroRNA hsa-miR-6792-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-04 1.00E+00 4.37E-04 4.03E-03 12 103 "SPOP,VAT1L,IP6K1,ELMSAN1,FEM1B,GNAL,NEGR1,LIMS1,MYCN,HSPA4L,PARD3,ITM2C" MicroRNA hsa-miR-1286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-04 1.00E+00 4.37E-04 4.03E-03 12 103 "DDR1,SNX29,RABL2A,PACSIN2,SHISA6,KCNH2,MEIS1,PKM,SMOX,MTRF1L,MGRN1,GDPD5" MicroRNA hsa-miR-548o-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-04 1.00E+00 4.40E-04 4.05E-03 13 118 "ELMO1,MAMLD1,PLEKHA1,ZNF585B,SCIN,EPB41L4B,SGSM1,FNIP1,ATF7IP,PEG10,ZMAT3,TUBB2A,MFF" MicroRNA hsa-miR-5787:Functional MTI Functional MTI miRTarbase 3.69E-04 1.00E+00 4.43E-04 4.08E-03 17 182 "CEP126,ARHGDIA,METTL6,RGS6,MYADM,CELF1,IRAK3,IBA57,KCNH2,MMP17,PKM,PEX2,KLHDC8A,ELP2,KIAA0895L,ZNF24,TMEM63C" MicroRNA hsa-miR-92b*:mirSVR_highEffct hsa-miR-92b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.73E-04 1.00E+00 4.48E-04 4.13E-03 10 75 "ACHE,PCDH10,SUGT1P4-STRA6LP-CCDC180,TPP1,B4GALNT1,IFT122,TMEM150C,TPCN2,SPHK2,CASC15" MicroRNA hsa-miR-1182:Functional MTI Functional MTI miRTarbase 3.73E-04 1.00E+00 4.48E-04 4.13E-03 10 75 "TEX22,SEC14L5,KLHL3,RCAN1,ZNF546,RBBP6,FAM214B,BDP1,USP22,PRDM10" MicroRNA hsa-miR-629-5p:Functional MTI Functional MTI miRTarbase 3.82E-04 1.00E+00 4.59E-04 4.22E-03 9 62 "CFLAR,CSNK1E,RASSF8,NFYA,MTRF1L,PTPRB,ZEB1,AKTIP,PARD3" MicroRNA hsa-miR-4258:mirSVR_highEffct hsa-miR-4258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.82E-04 1.00E+00 4.59E-04 4.22E-03 9 62 "NDRG2,ADAM15,CBR1,ARMCX4,NELFCD,AP4B1,NCKAP1L,NEU4,WIPF1" MicroRNA hsa-miR-6766-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.84E-04 1.00E+00 4.61E-04 4.24E-03 7 38 "PUM1,RAB30,RASSF8,MBNL1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-564:PITA hsa-miR-564:PITA_TOP PITA 3.84E-04 1.00E+00 4.61E-04 4.24E-03 7 38 "PPFIA3,CABP1,PHC2,PTCH1,SP2,ZIC2,TMEM63C" MicroRNA "CTCTATG,MIR-368:MSigDB" "CTCTATG,MIR-368:MSigDB" MSigDB 3.84E-04 1.00E+00 4.61E-04 4.24E-03 7 38 "CACNA1G,CAPN3,SEPT7,DLX1,MEF2C,RGS4,SATB2" MicroRNA hsa-miR-211-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-04 1.00E+00 4.77E-04 4.39E-03 13 119 "OGT,ARHGDIA,SV2B,ERBB2,IGF1,COMMD5,RETREG2,DDN,SLC37A2,PUM2,PPIL6,SLC30A3,RNF146" MicroRNA hsa-miR-553:PITA hsa-miR-553:PITA_TOP PITA 4.07E-04 1.00E+00 4.89E-04 4.50E-03 8 50 "C2CD2L,FOXO3,PPP2R2B,CUX2,NR2C2,RPRM,ZBTB14,PHTF2" MicroRNA hsa-miR-6841-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-04 1.00E+00 4.89E-04 4.50E-03 8 50 "TNRC6C,CALM1,TPP1,TNFAIP8L3,SHISA6,MEIS1,TRIM67,SS18" MicroRNA hsa-miR-503-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-04 1.00E+00 4.89E-04 4.50E-03 8 50 "BRAP,TMEM184B,CSNK1G3,ZC3H11A,EGR3,C8orf37,LYVE1,L1CAM" MicroRNA hsa-miR-8077:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 4.98E-04 4.59E-03 10 76 "KIAA0408,IST1,SV2B,FGFR1,PKM,EPB41L4B,QDPR,CHD9,IQSEC2,TUBB2A" MicroRNA hsa-miR-4648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 4.98E-04 4.59E-03 10 76 "LONRF2,PPP1R16B,DCAF8,E2F6,NEGR1,PKM,PMP22,CAMTA2,LAT2,WNK2" MicroRNA hsa-miR-4254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 4.98E-04 4.59E-03 10 76 "RIMS4,UBXN2A,ABCC5,PHC2,ANKMY1,CRCP,PKM,STX1B,AGTPBP1,WBP2" MicroRNA hsa-miR-106b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 4.98E-04 4.59E-03 10 76 "MTMR3,CBS,DPH1,CHST15,ZNF638,LRP1B,NFE2L2,NUBPL,KDM4B,UBE3B" MicroRNA hsa-miR-5006-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 4.98E-04 4.59E-03 10 76 "CBS,BAG4,EXOG,KIAA1958,PIK3R1,PPARA,RPS6KA2,ZBTB43,SIN3B,ZNF28" MicroRNA hsa-miR-7155-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-04 1.00E+00 5.00E-04 4.60E-03 11 90 "ADD1,BMP7,CRLF1,DIS3L,ZNF385A,SOCS5,IP6K1,RASA4,ZNF491,KLHDC8A,UNC5B" MicroRNA hsa-miR-7855-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-04 1.00E+00 5.00E-04 4.60E-03 11 90 "PPP1R16B,DNAH9,ANKFY1,POLL,SHISAL1,KANSL1,SLC25A36,C12orf49,EPN2,ZNF70,GAN" MicroRNA hsa-miR-495-3p:Functional MTI Functional MTI miRTarbase 4.19E-04 1.00E+00 5.01E-04 4.62E-03 17 184 "MTA3,TMEFF1,MYADM,DGKB,DLC1,IL6R,MSANTD3-TMEFF1,MEIS1,NCAM2,OCRL,ABCB1,PRRT2,ZNF354C,TRIM67,MPRIP,ARL10,ADAMTS9" MicroRNA hsa-miR-1273:PITA hsa-miR-1273:PITA_TOP PITA 4.28E-04 1.00E+00 5.12E-04 4.71E-03 6 28 "AXIN2,EVI5L,ARHGEF6,ABCC5,PAN3,CPNE4" MicroRNA hsa-miR-6080:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-04 1.00E+00 5.12E-04 4.71E-03 6 28 "RNF157,MSANTD4,ADAM22,PDE4D,TROVE2,TMEM198" MicroRNA hsa-miR-1323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 5.16E-04 4.75E-03 13 120 "ELMO1,MAMLD1,PLEKHA1,ZNF585B,SCIN,EPB41L4B,SGSM1,FNIP1,ATF7IP,PEG10,ZMAT3,TUBB2A,MFF" MicroRNA hsa-miR-6866-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 5.16E-04 4.75E-03 9 63 "WDR35,ARHGDIA,MTMR3,STOML1,HSPA12B,CRCP,GPT2,UHRF1BP1L,TUBB2A" MicroRNA hsa-miR-758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 5.16E-04 4.75E-03 9 63 "USP6NL,E2F5,DCTN4,STAMBP,OLA1,ZNF655,SETD5,ZNF415,ZNF195" MicroRNA hsa-miR-1225-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-04 1.00E+00 5.34E-04 4.92E-03 15 152 "ELFN2,HCN2,TMEM184B,DMPK,ZNF585B,GPR75,MUM1,METTL21A,MSANTD2,RPS6KA2,STX1B,CSRNP3,TAL1,SZT2,TMEM63C" MicroRNA hsa-miR-6731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-04 1.00E+00 5.41E-04 4.98E-03 7 39 "INTS2,OSBPL1A,CCDC144A,GABRG2,SYT17,SHISA6,HNRNPA3" MicroRNA hsa-miR-378c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-04 1.00E+00 5.41E-04 4.98E-03 7 39 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,SEC31A,CELF4" MicroRNA hsa-miR-3151-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-04 1.00E+00 5.41E-04 4.98E-03 7 39 "ELFN2,ADD2,CFL2,OSBPL3,HUNK,RPL7L1,UGT8" MicroRNA hsa-miR-604:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-04 1.00E+00 5.41E-04 4.98E-03 7 39 "NCOA1,SV2B,MRVI1,SRRM4,MSI1,NFIX,ZNF610" MicroRNA hsa-miR-638:mirSVR_highEffct hsa-miR-638:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.62E-04 1.00E+00 5.52E-04 5.09E-03 10 77 "NCKAP5,ADGRF5,SNCAIP,SPEG,FUT10,KCNB1,MYO7A,WDR47,AP4E1,ZNF195" MicroRNA hsa-miR-146b-5p:Functional MTI Functional MTI miRTarbase 4.67E-04 1.00E+00 5.58E-04 5.14E-03 13 121 "NSL1,EGFR,ERBB4,MRPL10,KIT,MMP16,MPP2,MYO6,NOVA1,KCTD15,ELP2,NSFL1C,TLR4" MicroRNA hsa-miR-628-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.68E-04 1.00E+00 5.59E-04 5.14E-03 8 51 "RTTN,KIAA0408,SEMA3D,IRAK4,CRCP,MBNL1,CHD9,NELFE" MicroRNA hsa-miR-923:PITA hsa-miR-923:PITA_TOP PITA 4.74E-04 1.00E+00 5.66E-04 5.21E-03 5 19 "FMNL2,TRMT9B,PPARGC1A,ROBO1,SYN2" MicroRNA hsa-miR-8074:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-04 1.00E+00 5.66E-04 5.21E-03 5 19 "BACH1,TNRC6A,KCTD15,PEX2,ARC" MicroRNA hsa-miR-4428:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-04 1.00E+00 5.74E-04 5.28E-03 14 137 "TTLL9,TOGARAM2,ZNF385A,CNTNAP2,SLITRK5,MSL1,C2CD4C,ITPKB,MID1,PRRT2,RFX3,SHMT2,LGI3,ZFP1" MicroRNA hsa-miR-499a-5p:Functional MTI Functional MTI miRTarbase 4.86E-04 1.00E+00 5.79E-04 5.34E-03 9 64 "AXIN2,LIN54,DGKG,CELF1,IQGAP2,KPNA5,MAPK10,ZNF844,ASAP3" MicroRNA hsa-miR-885-5p:Functional MTI Functional MTI miRTarbase 4.86E-04 1.00E+00 5.79E-04 5.34E-03 9 64 "RUNX1T1,GREB1,EIF4G2,C8orf37,HHIPL1,SHC3,NWD1,TBCEL,USP22" MicroRNA hsa-miR-569:Functional MTI Functional MTI miRTarbase 4.86E-04 1.00E+00 5.79E-04 5.34E-03 9 64 "EIF5,NCALD,TUBA1B,HLF,GPSM2,FITM2,UBR7,SLC25A36,ZNF711" MicroRNA hsa-miR-767-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.04E-04 1.00E+00 6.01E-04 5.54E-03 17 187 "GAPVD1,ELMSAN1,FKTN,FUT9,DOT1L,KIAA1958,AGBL5,MYCN,ENPP2,STRN3,NWD1,KLHL11,FNIP1,PEG10,MCF2L2,TRPS1,TUBB2A" MicroRNA hsa-miR-206:Functional MTI Functional MTI miRTarbase 5.06E-04 1.00E+00 6.03E-04 5.55E-03 13 122 "CLCN3,RIMS4,HDAC4,MATR3,MYEF2,COQ7,ZBED3,STAMBP,FYB1,GPD2,DDX19B,FNDC3A,WBP2" MicroRNA hsa-miR-541:PITA hsa-miR-541:PITA_TOP PITA 5.13E-04 1.00E+00 6.12E-04 5.63E-03 10 78 "KCNAB3,FOXN3,CABP1,ZNF385A,CLIP3,TNRC6A,GRIN2D,CNOT4,ST5,KIAA0930" MicroRNA hsa-miR-4429:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.13E-04 1.00E+00 6.12E-04 5.63E-03 10 78 "ADD1,SEMA7A,TNRC6C,C2CD2,SYNCRIP,SRCAP,RBPJ,HSPA4L,TAL1,ARL10" MicroRNA hsa-miR-8073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.17E-04 1.00E+00 6.16E-04 5.68E-03 14 138 "SMIM17,ARHGDIA,DNAH17,MTMR3,CCNT1,UFM1,ZNF234,HAS2,SEPT4,KANSL3,FNBP1,UNC5B,PRRC2C,ZNF70" MicroRNA hsa-miR-18b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-04 1.00E+00 6.22E-04 5.73E-03 6 29 "TEX22,SLC24A4,GPD1,XRRA1,ZMAT3,WBP2" MicroRNA hsa-miR-127-3p:Functional MTI Functional MTI miRTarbase 5.23E-04 1.00E+00 6.22E-04 5.73E-03 6 29 "USP35,SEPT7,NBEA,MAPK4,SEC31A,ACTR3B" MicroRNA hsa-miR-4738-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-04 1.00E+00 6.22E-04 5.73E-03 6 29 "CPNE5,TMEM164,GNG4,GPT2,SAMD5,SGK1" MicroRNA hsa-miR-187:PITA hsa-miR-187:PITA_TOP PITA 5.23E-04 1.00E+00 6.22E-04 5.73E-03 6 29 "NDRG3,LRFN1,HIPK3,PAN3,PPARGC1A,FLRT2" MicroRNA hsa-miR-6851-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-04 1.00E+00 6.33E-04 5.83E-03 7 40 "TMEM132B,SLC24A4,KALRN,ARHGEF2,RAB30,MINDY2,PPP3CC" MicroRNA hsa-miR-7975:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-04 1.00E+00 6.33E-04 5.83E-03 7 40 "RNF157,AMPD3,FREM1,KANSL1,SCN2B,GALNT10,ZNF34" MicroRNA hsa-miR-1268a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-04 1.00E+00 6.37E-04 5.87E-03 8 52 "CAMK2G,CDC25B,EVI5L,NDST3,EPB41,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-651-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-04 1.00E+00 6.49E-04 5.98E-03 9 65 "CNN3,KIAA0408,SPATA2,ANKRD46,HSPA12B,ADAM28,CHIC1,ZC3H12B,TUBB2A" MicroRNA hsa-miR-4296:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-04 1.00E+00 6.49E-04 5.98E-03 9 65 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-6869-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.47E-04 1.00E+00 6.50E-04 5.99E-03 13 123 "CD86,RNF14,UBXN2A,ZDHHC15,METTL21A,SH3TC2,PEX26,TMCC1,THRA,TUBB2A,RPL7L1,ZFP37,ZNF708" MicroRNA hsa-miR-5587-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-04 1.00E+00 6.58E-04 6.06E-03 11 93 "TRMT9B,LRCH2,HAPLN1,CELF1,SEPT9,RAD51D,C12orf49,NUBPL,ZBTB43,ZNF621,SGK3" MicroRNA hsa-miR-7162-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-04 1.00E+00 6.58E-04 6.06E-03 11 93 "LURAP1,LRRFIP1,LETMD1,TM9SF4,FKTN,LILRA2,SHISAL1,NCOA7,PSAT1,HSPA4L,GORASP1" MicroRNA hsa-miR-3605-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.62E-04 1.00E+00 6.68E-04 6.15E-03 12 108 "GAPVD1,SYNCRIP,KIF5A,NUCB2,GPR137C,ZNF426,PPP2R5E,MTMR10,C1orf109,MRAS,PEG10,TPM1" MicroRNA hsa-miR-4663:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-04 1.00E+00 6.76E-04 6.22E-03 10 79 "RGS11,UBXN2A,KIAA0408,IST1,SV2B,EPB41L4B,MTMR10,QDPR,CHD9,PEX26" MicroRNA hsa-miR-655-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.91E-04 1.00E+00 7.02E-04 6.46E-03 13 124 "NRXN3,ZNF385A,SEC14L5,TBC1D5,DBT,FAM198B,DDX19B,TJAP1,SLC11A2,PPP3CC,QDPR,PGBD4,CLDND1" MicroRNA hsa-miR-4266:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.07E-04 1.00E+00 7.20E-04 6.63E-03 11 94 "MTUS1,TOGARAM2,TNK2,KATNAL1,CHIC1,ZC3H12B,NELL2,PDE4D,POLR2F,ALG9,UNC5B" MicroRNA hsa-miR-4799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.07E-04 1.00E+00 7.20E-04 6.63E-03 11 94 "ZBTB10,ZNF555,KIAA0408,ARHGAP32,TMEM170A,SARAF,GCK,HNF4G,KITLG,FAM126B,TBCEL" MicroRNA hsa-miR-616-3p:Functional MTI Functional MTI miRTarbase 6.11E-04 1.00E+00 7.25E-04 6.67E-03 8 53 "CARNS1,BBOX1,USP37,SFMBT2,MRO,MIER3,CNNM2,RBM26" MicroRNA hsa-miR-7704:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.11E-04 1.00E+00 7.25E-04 6.67E-03 8 53 "CPNE5,IP6K1,FLYWCH1,COMMD5,TBC1D25,ZNF426,RGS12,ARC" MicroRNA hsa-miR-6886-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "ATP2A2,CRY2,SOCS5,GAPVD1,TXNL4A,FAM107A,MAPT,NPTX2,SNRK" MicroRNA hsa-miR-4322:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-1208:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "TMEM132B,ABCD2,DOT1L,FYN,SALL1,HSPA4L,FAM126B,ZNF621,AMACR" MicroRNA hsa-miR-590-5p:Functional MTI Functional MTI miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "TMEM170A,FGF12,FOXO3,CHL1,ZNF678,MBNL1,PURG,KANSL3,ATF7IP" MicroRNA hsa-miR-4265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-5009-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-04 1.00E+00 7.25E-04 6.68E-03 9 66 "ADD2,ST6GALNAC3,CIT,PTPRB,SH3TC2,RPL15,ST6GAL1,ZMAT3,RUNDC3B" MicroRNA hsa-miR-6800-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.22E-04 1.00E+00 7.36E-04 6.78E-03 7 41 "KIAA1324,CCNT1,TMEM170A,ELMSAN1,EDN1,ZNF585B,DICER1" MicroRNA hsa-miR-4782-3p:Functional MTI Functional MTI miRTarbase 6.22E-04 1.00E+00 7.36E-04 6.78E-03 7 41 "PUM1,RAB30,RASSF8,MBNL1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-643:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.22E-04 1.00E+00 7.36E-04 6.78E-03 7 41 "BACH1,TBPL1,VCAN,MPRIP,NACC2,VLDLR,SIGLEC10" MicroRNA hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA_TOP PITA 6.29E-04 1.00E+00 7.44E-04 6.85E-03 10 80 "KCNAB3,FOXN3,CABP1,ZNF385A,CLIP3,TNRC6A,GRIN2D,CNOT4,ST5,KIAA0930" MicroRNA hsa-miR-6504-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-04 1.00E+00 7.44E-04 6.85E-03 10 80 "ARHGDIA,SRRM4,IBA57,NFIX,PDE1B,NWD1,SEPHS1,FNBP1,ZNF610,ZNF24" MicroRNA hsa-miR-151a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 6.29E-04 1.00E+00 7.44E-04 6.85E-03 10 80 "PUM1,ZBTB24,NTRK3,SEPT8,CABIN1,STXBP4,ZNF711,ZBTB38,WNK3,FXR1" MicroRNA hsa-miR-4660:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-04 1.00E+00 7.44E-04 6.85E-03 10 80 "FAM13A,GLUL,KIAA1958,MBNL1,NBL1,RETREG2,TRIM67,WBP2,RUNDC3B,ACTR3B" MicroRNA hsa-miR-1538:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-04 1.00E+00 7.49E-04 6.90E-03 6 30 "ARHGDIA,LETMD1,BRSK1,ADAMTS13,IBA57,SEPT8" MicroRNA hsa-miR-5687:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-04 1.00E+00 7.49E-04 6.90E-03 6 30 "MAP4K4,CRCP,GPSM2,PRKAB2,FNIP1,RNF146" MicroRNA hsa-miR-4745-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-04 1.00E+00 7.49E-04 6.90E-03 6 30 "ARHGDIA,LETMD1,BRSK1,ADAMTS13,IBA57,SEPT8" MicroRNA hsa-miR-6890-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.38E-04 1.00E+00 7.54E-04 6.95E-03 13 125 "C6orf89,CPNE5,TBPL1,KIAA0586,POLL,GPR155,MPP2,ZNF426,GDPD1,C12orf49,PTGR2,PUM2,ZNF24" MicroRNA hsa-miR-152-3p:Functional MTI Functional MTI miRTarbase 6.72E-04 1.00E+00 7.94E-04 7.31E-03 15 158 "ALCAM,TRMT9B,STX16,CLOCK,CSF1,FGFR3,NEURL4,TNRC6A,ZIC5,CNOT4,NPTX1,BTBD3,CDK19,DICER1,FXR1" MicroRNA hsa-miR-551b:PITA hsa-miR-551b:PITA_TOP PITA 6.75E-04 1.00E+00 7.97E-04 7.34E-03 4 12 "ERBB4,PTK2,TMEM255A,PJA1" MicroRNA hsa-miR-638:PITA hsa-miR-638:PITA_TOP PITA 6.75E-04 1.00E+00 7.97E-04 7.34E-03 4 12 "SPEG,MIER3,WDR47,CELF4" MicroRNA hsa-miR-886-5p:PITA hsa-miR-886-5p:PITA_TOP PITA 6.75E-04 1.00E+00 7.97E-04 7.34E-03 4 12 "FOXN3,DMPK,EGR3,CAMKK2" MicroRNA hsa-miR-551a:PITA hsa-miR-551a:PITA_TOP PITA 6.75E-04 1.00E+00 7.97E-04 7.34E-03 4 12 "ERBB4,PTK2,TMEM255A,PJA1" MicroRNA "AGCGCAG,MIR-191:MSigDB" "AGCGCAG,MIR-191:MSigDB" MSigDB 6.75E-04 1.00E+00 7.97E-04 7.34E-03 4 12 "OGT,CHRD,MAGI1,EGR3" MicroRNA hsa-miR-619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-04 1.00E+00 8.08E-04 7.43E-03 9 67 "CBFA2T2,LRWD1,RBPJ,LIMS1,CDK19,PRRC2C,WBP2,SSBP2,ZNF154" MicroRNA hsa-miR-539-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-04 1.00E+00 8.08E-04 7.43E-03 9 67 "DST,CLTC,RCAN2,SRCAP,MKLN1,KANSL1,SS18,INTS3,ACTR3B" MicroRNA hsa-miR-499a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-04 1.00E+00 8.08E-04 7.43E-03 9 67 "CACNA1B,LIN54,DNAH9,MAMLD1,FEM1B,SRRM1,LIFR,MEF2C,FIGN" MicroRNA hsa-miR-129-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-04 1.00E+00 8.08E-04 7.43E-03 9 67 "NUMBL,RGS6,GAPVD1,DUSP9,E2F5,CACFD1,KCNB1,NPTX2,PDCD2" MicroRNA hsa-miR-134-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-04 1.00E+00 8.08E-04 7.43E-03 9 67 "TRMT9B,LONRF2,PYGO1,POLL,NOVA2,SHMT2,PEX26,ARC,WNK2" MicroRNA hsa-miR-365b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-04 1.00E+00 8.12E-04 7.47E-03 13 126 "ESYT2,ATP1B3,ZMYM4,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,KCNK3,ARHGAP26,LAT2,CFAP298" MicroRNA hsa-miR-3157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.95E-04 1.00E+00 8.19E-04 7.54E-03 8 54 "TEX22,ATP2A2,RGS6,CRCP,GPD1,MAPT,XRRA1,TRIM67" MicroRNA hsa-miR-345-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.95E-04 1.00E+00 8.19E-04 7.54E-03 10 81 "ZNF385A,TOM1,NEGR1,SLC35G1,LSAMP,PDPK1,UBR7,FNBP1,ZNF177,DHX33" MicroRNA hsa-miR-3064-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.95E-04 1.00E+00 8.19E-04 7.54E-03 10 81 "ARHGDIA,SRRM4,IBA57,NFIX,PDE1B,NWD1,SEPHS1,FNBP1,ZNF610,ZNF24" MicroRNA hsa-miR-25-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.05E-04 1.00E+00 8.31E-04 7.65E-03 18 210 "TRMT9B,ASPA,CACNA1B,CDR1,PLAA,NCOR2,FECH,NFIX,FXYD1,RBBP8,PTGR2,FNIP1,LIMS2,FNBP1,MCF2L2,SSBP2,USP1,TBC1D15" MicroRNA hsa-miR-654-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.17E-04 1.00E+00 8.45E-04 7.78E-03 15 159 "ELMSAN1,APH1A,ANKFY1,CRCP,GLI2,METTL21A,ZC3H12B,NFIX,GPR173,FXYD1,SPART,CLASP1,CRTC1,RICTOR,ITM2C" MicroRNA hsa-miR-6892-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.23E-04 1.00E+00 8.51E-04 7.84E-03 7 42 "NCKAP5,TAOK1,MYADM,TMCC1,FBXW11,TUBB2A,DHX33" MicroRNA hsa-miR-548av-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.26E-04 1.00E+00 8.55E-04 7.87E-03 11 96 "USP37,NUMB,BAG4,DNAL1,E2F6,FOXO3,PACSIN2,ELOVL5,KANSL1,SMARCAD1,MFF" MicroRNA hsa-miR-4327:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.26E-04 1.00E+00 8.55E-04 7.87E-03 11 96 "ASPA,PLAA,PLCXD3,TMEM170A,IRAK4,MTMR10,ZNF793,ROBO1,NFASC,PPIL6,USP1" MicroRNA hsa-miR-1238:PITA hsa-miR-1238:PITA_TOP PITA 7.62E-04 1.00E+00 8.96E-04 8.25E-03 6 31 "APBB2,ATP2B2,SYNJ1,LHX2,CSNK1G3,JAKMIP2" MicroRNA hsa-miR-3619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.62E-04 1.00E+00 8.96E-04 8.25E-03 6 31 "ADD1,OGT,C2orf72,IL6R,SHC3,MTMR10" MicroRNA hsa-miR-6813-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.64E-04 1.00E+00 8.98E-04 8.27E-03 9 68 "EIF4G3,DCAF8,DNAJB6,ITPKB,MAN2A2,PIK3C2A,C12orf49,ZNF34,ZNF70" MicroRNA hsa-miR-659-3p:Functional MTI Functional MTI miRTarbase 7.64E-04 1.00E+00 8.98E-04 8.27E-03 9 68 "PCDHGB4,DYNLL1,STX16,CD38,GPR155,MSR1,RPL15,SH3BP2,KLHL7" MicroRNA hsa-miR-802:Functional MTI Functional MTI miRTarbase 7.64E-04 1.00E+00 8.98E-04 8.27E-03 9 68 "COL4A5,FRY,SYNCRIP,TJAP1,STX1B,RPL7L1,ZNF711,ZNF708,PHTF2" MicroRNA hsa-miR-378g:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-04 1.00E+00 9.00E-04 8.29E-03 10 82 "RIPOR2,RUSC2,UFM1,ITPKB,PKM,PPP1R1A,BCAS3,STUM,BDP1,ZNF154" MicroRNA hsa-miR-936:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-04 1.00E+00 9.00E-04 8.29E-03 10 82 "COL4A5,RGS17,ZNF391,ZNF585B,MBNL1,MTRF1L,TMEM104,CLIP1,RGMB,WNK2" MicroRNA hsa-miR-933:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.81E-04 1.00E+00 9.18E-04 8.45E-03 5 21 "APAF1,BCAS1,TBC1D16,UBE2E3,AFF2" MicroRNA hsa-miR-1200:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.16E-04 1.00E+00 9.59E-04 8.83E-03 15 161 "ELFN2,RNF157,TNRC6C,CDC25B,CPS1,SIGLEC8,ZDHHC15,METTL21A,CHIC1,P2RX7,PEX26,ZMAT3,ZNF106,RPL7L1,UGT8" MicroRNA hsa-miR-591:Functional MTI Functional MTI miRTarbase 8.37E-04 1.00E+00 9.82E-04 9.04E-03 7 43 "ADD1,AASS,KATNAL1,KLHL23,ASTN2,ZEB1,ZMAT3" MicroRNA hsa-miR-3907:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.37E-04 1.00E+00 9.82E-04 9.04E-03 7 43 "RNF157,CDC25B,TBPL1,CSNK1E,KLHL11,HUNK,ZNF74" MicroRNA "GCAAGAC,MIR-431:MSigDB" "GCAAGAC,MIR-431:MSigDB" MSigDB 8.37E-04 1.00E+00 9.82E-04 9.04E-03 7 43 "NRG2,LRRC37A6P,NRCAM,DHX30,CAMTA1,LAMP5,NETO1" MicroRNA hsa-miR-3649:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.37E-04 1.00E+00 9.82E-04 9.04E-03 7 43 "ENTPD4,MRPL10,PCYOX1,ANKFY1,MTMR10,MYO18A,CYB561A3" MicroRNA hsa-miR-4679:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-04 1.00E+00 9.98E-04 9.19E-03 9 69 "DBN1,CHRDL1,RASGRP1,APC2,ATP13A4,ADAP1,SEPHS1,KLHL7,RPL7L1" MicroRNA hsa-miR-5004-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-04 1.00E+00 9.98E-04 9.19E-03 9 69 "SCML2,ANKFY1,ELP2,GALNT10,ZC3H4,THRA,ERCC6L2,TNS1,ZNF74" MicroRNA hsa-miR-432-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-04 1.00E+00 9.98E-04 9.19E-03 9 69 "MRPL10,SRRM4,NXPH3,NUCB2,PKM,C1orf109,NKAIN1,POGZ,TSN" MicroRNA hsa-miR-6774-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-04 1.00E+00 9.98E-04 9.19E-03 9 69 "SEMA7A,ARHGDIA,CACNA2D2,SUMF2,EPB41,CELF1,CRCP,CNNM2,ZKSCAN3" MicroRNA hsa-miR-6882-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-04 1.00E+00 9.98E-04 9.19E-03 9 69 "CALM1,USP6NL,FAM107B,FOXO3,CHIC1,CLDN11,EXD2,TUBB2A,ZXDA" MicroRNA hsa-miR-4264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.64E-04 1.00E+00 1.01E-03 9.32E-03 11 98 "PHF12,USP37,ZNF583,COL4A5,GABRG1,FITM2,ZNF844,RAP1GDS1,CXXC4,ZNF24,ZNF195" MicroRNA hsa-miR-4522:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.64E-04 1.00E+00 1.01E-03 9.32E-03 11 98 "ZNF555,GAPVD1,SGSM2,DCTN4,ZNF549,KATNAL1,ZNF678,CHST6,STK32A,PEG10,ADAMTS17" MicroRNA hsa-miR-551a:TargetScan hsa-miR-551a TargetScan 8.77E-04 1.00E+00 1.03E-03 9.46E-03 3 6 "HEYL,ERBB4,MEF2C" MicroRNA hsa-miR-551b-3p:TargetScan hsa-miR-551b-3p TargetScan 8.77E-04 1.00E+00 1.03E-03 9.46E-03 3 6 "HEYL,ERBB4,MEF2C" MicroRNA hsa-miR-26b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.89E-04 1.00E+00 1.04E-03 9.59E-03 8 56 "RCAN1,FEM1B,RNFT2,LIFR,NCAM2,NCR3LG1,ZNF793,KCNIP3" MicroRNA hsa-miR-6719-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.89E-04 1.00E+00 1.04E-03 9.59E-03 8 56 "CCNT1,PPP1R16B,RPS6KL1,HSPA12B,LSAMP,CHIC1,TMEM200C,CADM2" MicroRNA hsa-miR-4697-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.89E-04 1.00E+00 1.04E-03 9.59E-03 8 56 "SLC6A17,MTRF1L,SH3TC2,NMNAT2,SPART,ITPRID2,PRRC2C,LAT2" MicroRNA hsa-miR-371a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.06E-03 9.79E-03 6 32 "ADD1,FLT1,TPK1,AFF1,ADAM22,ZC3H12B" MicroRNA hsa-miR-424-3p:Functional MTI Functional MTI miRTarbase 9.09E-04 1.00E+00 1.06E-03 9.79E-03 6 32 "GABRB3,MAT2A,PDE4D,ALG1,TRIM16L,NETO2" MicroRNA hsa-miR-6881-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.06E-03 9.79E-03 6 32 "RNPS1,IBA57,KANSL1,ZFP30,AMBRA1,PEG10" MicroRNA hsa-miR-210-3p:TargetScan hsa-miR-210-3p TargetScan 9.09E-04 1.00E+00 1.06E-03 9.79E-03 6 32 "ELFN2,CPEB2,SCARA3,MEX3B,NFIX,HIF3A" MicroRNA hsa-miR-574-3p:PITA hsa-miR-574-3p:PITA_TOP PITA 9.09E-04 1.00E+00 1.06E-03 9.79E-03 6 32 "ATP2A2,CLTC,FBXL5,FHL1,STRN3,RXRA" MicroRNA hsa-miR-1271-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-04 1.00E+00 1.08E-03 9.97E-03 10 84 "PITPNM3,TUBD1,MALT1,TNRC6A,NPTX1,PFKFB3,ANKRD36,SIN3B,RPL7L1,EVI5" MicroRNA hsa-miR-187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-04 1.00E+00 1.08E-03 9.97E-03 10 84 "DMPK,RNPS1,FICD,USP51,GPR85,SLC25A36,ZFP1,TMCC1,SLC19A3,CIAPIN1" MicroRNA hsa-miR-4511:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-04 1.00E+00 1.08E-03 9.97E-03 10 84 "TMCC3,TAOK1,ISPD,GFER,GLUL,GRIK4,HAS2,LAMA2,AFF1,BDP1" MicroRNA hsa-miR-4261:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-04 1.00E+00 1.08E-03 9.97E-03 10 84 "ELFN2,CELF1,TVP23A,PDPK1,NCBP3,LIMCH1,TMPO,NDRG4,HNRNPA3,SPATA13" MicroRNA hsa-miR-517a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.47E-04 1.00E+00 1.11E-03 1.02E-02 4 13 "DBN1,PTK2B,NACC2,USP1" MicroRNA hsa-miR-6082:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.47E-04 1.00E+00 1.11E-03 1.02E-02 4 13 "ARHGAP32,DCTN4,ZFP30,BTBD3" MicroRNA hsa-miR-517c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.47E-04 1.00E+00 1.11E-03 1.02E-02 4 13 "DBN1,PTK2B,NACC2,USP1" MicroRNA hsa-miR-451:PITA hsa-miR-451:PITA_TOP PITA 9.64E-04 1.00E+00 1.13E-03 1.04E-02 7 44 "MAML1,EVL,MINDY2,SETD5,MPRIP,AKTIP,EMSY" MicroRNA hsa-miR-5579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.64E-04 1.00E+00 1.13E-03 1.04E-02 7 44 "NUMBL,TMEM170A,FAM98B,PURG,ATF7IP,PRRC2C,JMJD1C" MicroRNA hsa-miR-875-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.64E-04 1.00E+00 1.13E-03 1.04E-02 7 44 "TOGARAM2,ELMSAN1,EGFR,MALT1,OXR1,ITPRID2,SLC44A1" MicroRNA hsa-miR-601:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-04 1.00E+00 1.14E-03 1.05E-02 5 22 "NFS1,KLHL3,NR1D2,ZNF585B,TROVE2" MicroRNA hsa-miR-662:PITA hsa-miR-662:PITA_TOP PITA 9.80E-04 1.00E+00 1.14E-03 1.05E-02 5 22 "CNTNAP2,CHIC1,ZNF532,SGK1,TNS1" MicroRNA hsa-miR-4293:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.86E-04 1.00E+00 1.15E-03 1.06E-02 12 115 "DOCK11,ATP13A4,B4GALNT1,TDRKH,AGBL5,MMP17,CCSER2,NCBP3,ATXN2,TUBB2A,ZFAND5,AP3B2" MicroRNA hsa-miR-4771:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-03 1.00E+00 1.17E-03 1.08E-02 8 57 "ARHGDIA,COL9A1,ABCC5,RNFT2,CYP27C1,AFF1,XRRA1,VSNL1" MicroRNA hsa-miR-153-3p:Functional MTI Functional MTI miRTarbase 1.02E-03 1.00E+00 1.18E-03 1.09E-02 10 85 "USP6NL,NFE2L2,P2RY1,SATB1,SNCA,ZBTB43,SS18,SEPT8,RPL7L1,FXR1" MicroRNA hsa-miR-379-5p:Functional MTI Functional MTI miRTarbase 1.02E-03 1.00E+00 1.18E-03 1.09E-02 10 85 "SLC2A11,DNAL1,EDN1,TUBD1,POLL,TDRKH,DDX19B,MTRF1L,GDPD1,PTK2" MicroRNA hsa-miR-4802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-03 1.00E+00 1.18E-03 1.09E-02 10 85 "CCNT1,TOGARAM2,MATR3,SEPT9,ZBTB45,GPR137C,PURG,MINDY2,STX1B,ZFAND5" MicroRNA hsa-miR-7159-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-03 1.00E+00 1.18E-03 1.09E-02 10 85 "TNRC6C,RIMS4,ZNF585B,KCNMB4,NEGR1,IGF1,ZNF678,NPTX1,POLG,TET1" MicroRNA hsa-miR-892b:Functional MTI Functional MTI miRTarbase 1.05E-03 1.00E+00 1.22E-03 1.12E-02 9 71 "TBC1D14,LDHD,SEC24C,KIAA1841,MSANTD2,FNBP1,NSD1,ZMAT3,ZNF24" MicroRNA hsa-miR-328-3p:Functional MTI Functional MTI miRTarbase 1.06E-03 1.00E+00 1.24E-03 1.14E-02 13 132 "TMEM132B,DYNLL1,ARHGEF25,ARHGEF2,ABCG2,POM121,TCERG1,KCNH2,MAP4,MMP16,PKM,TRIM67,UBTF" MicroRNA "TAGAACC,MIR-182:MSigDB" "TAGAACC,MIR-182:MSigDB" MSigDB 1.08E-03 1.00E+00 1.25E-03 1.16E-02 6 33 "CREM,FAM107B,FAM78B,AMZ2P1,ZNF532,DOCK9" MicroRNA hsa-miR-5009-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-03 1.00E+00 1.25E-03 1.16E-02 6 33 "LRWD1,E2F6,HIPK3,RNF165,FITM2,MYO18A" MicroRNA hsa-miR-624-3p:Functional MTI Functional MTI miRTarbase 1.11E-03 1.00E+00 1.29E-03 1.19E-02 11 101 "PCDH19,TXNDC16,APAF1,DMPK,IBA57,ZNF713,P2RY1,CCSER2,ALG9,NR2E1,CADM2" MicroRNA hsa-miR-450b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-03 1.00E+00 1.30E-03 1.19E-02 10 86 "CLOCK,FUT10,STMN1,CHST6,GPR137C,MINDY2,GALNT10,FAM126B,STAU1,NSD1" MicroRNA hsa-miR-4772-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-03 1.00E+00 1.31E-03 1.21E-02 8 58 "SUCO,SMC2,GLUL,PRRT2,ALG9,PEAR1,WBP2,TSN" MicroRNA hsa-miR-5689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-03 1.00E+00 1.31E-03 1.21E-02 8 58 "ISPD,QKI,SOCS5,SLC12A6,DNAJB6,P2RY1,OLA1,STX1B" MicroRNA "AGTCAGC,MIR-345:MSigDB" "AGTCAGC,MIR-345:MSigDB" MSigDB 1.13E-03 1.00E+00 1.31E-03 1.21E-02 8 58 "VAT1L,CPEB2,OGA,PFKFB2,PRRC2C,SSBP2,UBE2H,SOCS4" MicroRNA hsa-miR-3155a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-03 1.00E+00 1.33E-03 1.23E-02 12 117 "ABCF1,PREPL,EXOG,GPR155,MAT2A,C12orf49,ELP2,NUBPL,ATF7IP,ANKRD36,ZNF621,SGK3" MicroRNA hsa-miR-3155b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-03 1.00E+00 1.33E-03 1.23E-02 12 117 "ABCF1,PREPL,EXOG,GPR155,MAT2A,C12orf49,ELP2,NUBPL,ATF7IP,ANKRD36,ZNF621,SGK3" MicroRNA hsa-miR-5008-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-03 1.00E+00 1.40E-03 1.29E-02 11 102 "SLC24A4,TRMT9B,CBARP,GREB1,SLC43A2,RAB30,ZNF491,IQSEC3,KCNIP3,RPL7L1,INTS3" MicroRNA hsa-miR-1538:mirSVR_highEffct hsa-miR-1538:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-03 1.00E+00 1.42E-03 1.30E-02 10 87 "EPS15L1,LETMD1,SH2B1,DHRS4,NF1,FSD1,CEP97,TPCN2,MTMR14,RIMBP2" MicroRNA hsa-miR-658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.46E-03 1.35E-02 15 168 "SLC24A4,CDR1,NCOR2,ZNF549,FECH,PRRC2B,FXYD1,RBBP8,PTGR2,FNIP1,LIMS2,FNBP1,MCF2L2,NACC2,TBC1D15" MicroRNA hsa-miR-454-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.47E-03 1.35E-02 8 59 "AK2,ASGR1,LDHD,RCAN1,PLEKHA1,HSF2,TMPO,AP3B2" MicroRNA hsa-miR-1256:Non-Functional MTI Non-Functional MTI miRTarbase 1.26E-03 1.00E+00 1.47E-03 1.35E-02 7 46 "OGT,ARHGEF7,EID2B,ZIC5,TRIM68,SALL1,SLC6A8" MicroRNA hsa-miR-3913-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.47E-03 1.35E-02 7 46 "SEMA4G,ARRB1,FEM1B,FRY,ADAM28,FICD,CADM2" MicroRNA hsa-miR-4474-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.47E-03 1.35E-02 7 46 "PHF14,FRY,CEP85L,GPSM2,ITPRID2,KLHL7,SIRT1" MicroRNA hsa-miR-378e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-378i:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-378h:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-7107-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "KLHL3,RPS6KL1,CYP27C1,KSR2,PALM,ZMAT4" MicroRNA hsa-miR-378f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-378d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.47E-03 1.35E-02 6 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-3167:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-03 1.00E+00 1.48E-03 1.37E-02 9 73 "TAOK1,ABCG2,PYGO1,SRRM4,CBX1,MAT2A,P2RX7,P2RY1,ALG1" MicroRNA hsa-miR-7109-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-03 1.00E+00 1.48E-03 1.37E-02 9 73 "IGDCC4,CFL2,MRO,FGF1,SAMD5,SLC6A8,SMARCC2,ZNF225,URM1" MicroRNA hsa-miR-8070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-03 1.00E+00 1.48E-03 1.37E-02 9 73 "INTS2,COPB2,DBN1,TNRC6A,ADAP1,ZNF181,RNASEL,CLIP1,TPCN2" MicroRNA hsa-miR-6800-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-03 1.00E+00 1.48E-03 1.37E-02 9 73 "SORCS2,ENTPD4,CSNK1G3,KIAA0408,CHRDL1,PDLIM5,TRIM67,MAPKBP1,SPATA13" MicroRNA hsa-miR-675:PITA hsa-miR-675:PITA_TOP PITA 1.29E-03 1.00E+00 1.49E-03 1.37E-02 4 14 "MARK4,ZNF385A,SLC29A4,SNX22" MicroRNA hsa-miR-6090:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-03 1.00E+00 1.54E-03 1.42E-02 10 88 "ELFN2,E2F6,ANKFY1,PRRC2B,NEGR1,NPTX2,PKD1,CAMTA2,SEPT8,RPRM" MicroRNA hsa-miR-1288-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-03 1.00E+00 1.54E-03 1.42E-02 10 88 "C1QTNF3,IGDCC4,ISPD,UFM1,CAMKK2,ZNF713,MYO18A,NEK4,FAM208A,SPATA13" MicroRNA hsa-miR-556-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-03 1.00E+00 1.63E-03 1.50E-02 8 60 "SLC24A4,TRMT9B,PITPNM3,MTX3,ZBTB49,TROVE2,STXBP4,PHTF2" MicroRNA hsa-miR-6813-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-03 1.00E+00 1.63E-03 1.51E-02 9 74 "TMEM184B,NCOR2,STAMBP,PRRC2B,PKD1,PKM,KCTD15,MTRF1L,INTS3" MicroRNA hsa-miR-6798-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-03 1.00E+00 1.65E-03 1.52E-02 12 120 "NDRG3,RNF157,SYT13,NCOR2,EIF4G1,CELF1,GFER,NCR3LG1,SARS,NFASC,UBTF,ITM2C" MicroRNA hsa-miR-4728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-03 1.00E+00 1.67E-03 1.53E-02 7 47 "ARMC12,NFS1,FERMT2,MMP17,FAM98B,AGTPBP1,TOM1L2" MicroRNA hsa-miR-3682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-03 1.00E+00 1.67E-03 1.53E-02 7 47 "ARSE,SMC2,ZNF680,CNNM2,TMEM200C,KIF21A,TCEA1" MicroRNA hsa-miR-4256:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-03 1.00E+00 1.72E-03 1.58E-02 6 35 "CCPG1,GPER1,KCNN1,SYTL4,LSAMP,CBX5" MicroRNA hsa-miR-1269a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-03 1.00E+00 1.72E-03 1.58E-02 6 35 "ESYT2,E2F6,RNF165,KCTD15,FITM2,MYO18A" MicroRNA hsa-miR-378b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-03 1.00E+00 1.72E-03 1.58E-02 6 35 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-423-3p:PITA hsa-miR-423-3p:PITA_TOP PITA 1.49E-03 1.00E+00 1.72E-03 1.59E-02 5 24 "LYPD1,FRY,EPB41L4B,VLDLR,PDSS2" MicroRNA hsa-miR-521:Functional MTI Functional MTI miRTarbase 1.49E-03 1.00E+00 1.72E-03 1.59E-02 5 24 "IPCEF1,INPP5B,KANSL1,CARF,RHBDL3" MicroRNA hsa-miR-4757-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-03 1.00E+00 1.73E-03 1.60E-02 15 171 "ZNF578,ARHGDIA,ELMSAN1,GPD1,HAS2,PIK3C2A,ZNF426,C12orf49,ZNF568,HSPA4L,GPRIN3,ZNF34,CBX5,ZNF70,HNRNPA3" MicroRNA hsa-miR-6744-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-03 1.00E+00 1.73E-03 1.60E-02 15 171 "ZNF578,ARHGDIA,ELMSAN1,GPD1,HAS2,PIK3C2A,ZNF426,C12orf49,ZNF568,HSPA4L,GPRIN3,ZNF34,CBX5,ZNF70,HNRNPA3" MicroRNA hsa-miR-6751-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-03 1.00E+00 1.76E-03 1.62E-02 11 105 "ARHGDIA,DBT,DOT1L,NLE1,DIRAS2,HSD11B1L,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1" MicroRNA hsa-miR-3186-5p:mirSVR_highEffct hsa-miR-3186-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-03 1.00E+00 1.76E-03 1.62E-02 11 105 "SOCS5,EDIL3,APH1A,UBE2E3,BTN2A1,MYLK2,NME4,KIAA0895L,ARX,CEP68,EML6" MicroRNA hsa-miR-323a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-03 1.00E+00 1.79E-03 1.65E-02 9 75 "SEMA7A,CBR1,SOCS5,F5,STMN1,GPSM2,FNDC3A,TRPS1,ZXDA" MicroRNA hsa-miR-5007-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-03 1.00E+00 1.79E-03 1.65E-02 9 75 "WDR35,ANKRD46,FRMD3,SALL1,KLHL4,BHLHB9,UBE3A,VLDLR,ZNF711" MicroRNA hsa-miR-1290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-03 1.00E+00 1.79E-03 1.65E-02 9 75 "ADD2,TAOK1,BCL7A,CLOCK,PYGO1,P2RY1,MPRIP,STAU1,MPPE1" MicroRNA hsa-miR-320e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-03 1.00E+00 1.81E-03 1.67E-02 8 61 "SEMA7A,CCNT1,SRCAP,ZNF491,SOX11,ARL10,ZNF70,ITM2C" MicroRNA "CCACACA,MIR-147:MSigDB" "CCACACA,MIR-147:MSigDB" MSigDB 1.57E-03 1.00E+00 1.81E-03 1.67E-02 8 61 "ATP1A1,MYLK2,ZNF827,PDPK1,RGS3,ROBO2,CAMTA1,SLC44A1" MicroRNA hsa-miR-6815-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-03 1.00E+00 1.81E-03 1.67E-02 8 61 "LURAP1,ZNF445,TM9SF4,LIN54,RBPJ,MTRF1L,SEPT4,ZNF331" MicroRNA hsa-miR-5700:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-03 1.00E+00 1.82E-03 1.68E-02 10 90 "FZD9,TNRC6C,ZBED3,KIAA1841,ZIC5,ZNF678,PURG,TROVE2,TNS1,ZNF711" MicroRNA hsa-miR-1268b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-03 1.00E+00 1.88E-03 1.73E-02 7 48 "CDC25B,EVI5L,NDST3,EPB41,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-6815-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-03 1.00E+00 1.97E-03 1.81E-02 9 76 "C1QTNF1,TMEM170A,ANKFY1,MTRF1L,RAP1GDS1,SLC2A5,KIAA0930,WBP2,BCL2L13" MicroRNA hsa-miR-6869-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-03 1.00E+00 1.97E-03 1.81E-02 4 15 "PDZD4,LETMD1,FKTN,NFIX" MicroRNA hsa-miR-138-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-03 1.00E+00 1.98E-03 1.82E-02 10 91 "PHF12,DDX46,RCAN2,TNRC6A,MBNL1,PPM1L,CCSER2,TRAPPC13,VPS13A,RPL7L1" MicroRNA hsa-miR-6833-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-03 1.00E+00 1.98E-03 1.82E-02 10 91 "LDHD,SRSF11,KIAA0040,ZC3H11A,C8orf37,CRCP,GPT2,MYO18A,ZNF106,BCL2L13" MicroRNA hsa-miR-1269b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "ESYT2,E2F6,RNF165,KCTD15,FITM2,MYO18A" MicroRNA hsa-miR-4740-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "ESYT2,CBARP,E2F6,TDRKH,RNF165,KCTD15" MicroRNA hsa-miR-4632-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "CCPG1,APC2,RASL10A,BRSK1,RADIL,SZT2" MicroRNA hsa-miR-1301-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "FRMD5,SHISA6,SNX10,VPS13A,ADAMTS17,GPRIN3" MicroRNA hsa-miR-6831-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "ZBTB10,SLC35G1,METTL21A,C12orf49,KAT6B,TPM1" MicroRNA hsa-miR-6502-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-03 1.00E+00 1.99E-03 1.83E-02 6 36 "FRMD5,SHISA6,SNX10,VPS13A,ADAMTS17,GPRIN3" MicroRNA hsa-miR-3147:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-03 1.00E+00 2.01E-03 1.85E-02 8 62 "XKR4,LDHD,PDE3A,MINDY2,FAM126B,STAU1,SULF2,NSD1" MicroRNA hsa-miR-622:Functional MTI Functional MTI miRTarbase 1.78E-03 1.00E+00 2.05E-03 1.88E-02 11 107 "BEND6,ZNF578,DISC1,KCNN3,NCR3LG1,ZNF844,SALL1,SCP2,UNC5B,KLHL7,ZNF195" MicroRNA hsa-miR-1178-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-03 1.00E+00 2.12E-03 1.95E-02 7 49 "ZNF578,ARHGAP22,OGG1,PEG10,CLDND1,DPYSL5,PRDM10" MicroRNA hsa-miR-3661:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-03 1.00E+00 2.12E-03 1.95E-02 7 49 "SFMBT2,LRWD1,SYNCRIP,SYTL4,MAT2A,KITLG,WBP2" MicroRNA hsa-miR-6877-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-03 1.00E+00 2.12E-03 1.95E-02 7 49 "NCBP3,LIMS2,ZKSCAN3,SP2,MPRIP,BHLHB9,TMEM63C" MicroRNA hsa-miR-4274:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-03 1.00E+00 2.12E-03 1.95E-02 7 49 "CASK,BAG4,NCOR2,SOCS5,ZC3H14,ATXN2,ANKRD36" MicroRNA hsa-miR-1284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-03 1.00E+00 2.12E-03 1.95E-02 7 49 "MTA3,SPAG9,NFS1,RCAN2,PRRC2B,INPP5B,KIF13A" MicroRNA hsa-miR-6865-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-03 1.00E+00 2.15E-03 1.98E-02 9 77 "C1QTNF1,TMEM170A,ANKFY1,MTRF1L,RAP1GDS1,SLC2A5,KIAA0930,WBP2,BCL2L13" MicroRNA hsa-miR-299-5p:Functional MTI Functional MTI miRTarbase 1.94E-03 1.00E+00 2.23E-03 2.05E-02 8 63 "ZBTB10,STX16,PLXNC1,DCTN4,TCERG1,TNRC6A,ROBO1,SPP1" MicroRNA hsa-miR-4760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-03 1.00E+00 2.23E-03 2.05E-02 8 63 "CDK13,FCF1,RAB40B,RBPJ,SH3TC2,SOX11,USP22,ZNF74" MicroRNA hsa-miR-4658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-03 1.00E+00 2.23E-03 2.05E-02 8 63 "DNAH17,FOXN3,TMEM184B,LONRF1,KATNAL1,PLEC,MGRN1,NSD1" MicroRNA hsa-miR-8061:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-03 1.00E+00 2.23E-03 2.05E-02 8 63 "CDK13,FCF1,RAB40B,RBPJ,SH3TC2,SOX11,USP22,ZNF74" MicroRNA hsa-miR-542-3p:Functional MTI Functional MTI miRTarbase 1.99E-03 1.00E+00 2.29E-03 2.11E-02 15 176 "KIAA1324,CDC14B,BMP7,CACNA1B,ZNF555,TBPL1,KIAA0408,PIK3R1,STK32A,TMEM145,MCF2L2,MGRN1,SSBP2,USP1,SLC30A4" MicroRNA hsa-miR-1307:mirSVR_highEffct hsa-miR-1307:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.00E-03 1.00E+00 2.29E-03 2.11E-02 6 37 "ZNF385A,EIF1,GLI2,CLASRP,TAGLN3,SIN3B" MicroRNA hsa-miR-6730-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-03 1.00E+00 2.32E-03 2.13E-02 10 93 "RNF157,FZD9,CRY2,FUT10,TJAP1,ZNF827,PKM,INAVA,ZMAT3,UBC" MicroRNA hsa-miR-516b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-03 1.00E+00 2.32E-03 2.13E-02 10 93 "LURAP1,LRRFIP1,TM9SF4,FKTN,LILRA2,SHISAL1,NCOA7,PSAT1,HSPA4L,GORASP1" MicroRNA hsa-miR-3922-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-03 1.00E+00 2.32E-03 2.13E-02 10 93 "DBT,COQ7,CELF1,ZNF274,RAB30,FICD,HAS2,PKM,SP4,USP22" MicroRNA hsa-miR-6864-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-03 1.00E+00 2.35E-03 2.16E-02 9 78 "TMCC3,HCN2,CA8,DUSP9,LIFR,MAT2A,CLDN11,EPB41L4B,SP2" MicroRNA hsa-miR-3169:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-03 1.00E+00 2.38E-03 2.20E-02 7 50 "SPOP,ABCD2,LDB2,CREM,SCML2,NFIX,TMCC1" MicroRNA hsa-miR-597-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-03 1.00E+00 2.38E-03 2.20E-02 7 50 "AKAP12,HS6ST3,EPDR1,BTBD3,NMNAT2,PRRC2C,WRN" MicroRNA hsa-miR-3141:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-03 1.00E+00 2.38E-03 2.20E-02 7 50 "ELFN2,BAIAP3,MTSS1L,CPLX1,NFIX,PEX26,ARC" MicroRNA hsa-miR-6790-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-03 1.00E+00 2.46E-03 2.26E-02 8 64 "DNAH17,FOXN3,TMEM184B,LONRF1,KATNAL1,PLEC,MGRN1,NSD1" MicroRNA hsa-miR-3127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-03 1.00E+00 2.46E-03 2.26E-02 8 64 "PRX,SEC16A,ERBB2,TNRC6A,KPNA5,RMI1,GALNT10,SLC30A3" MicroRNA hsa-miR-6740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-03 1.00E+00 2.46E-03 2.26E-02 8 64 "CA8,VXN,PITPNM3,FEM1B,PGBD4,BDP1,ERBIN,EXOC7" MicroRNA hsa-miR-4709-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-03 1.00E+00 2.48E-03 2.28E-02 12 126 "USP37,PTCH2,AP1M1,CPS1,PLXNA4,DCAF8,CNNM2,ZSCAN2,MSANTD2,WRN,ZNF138,STOX2" MicroRNA hsa-miR-147b:PITA hsa-miR-147b:PITA_TOP PITA 2.21E-03 1.00E+00 2.53E-03 2.33E-02 4 16 "PPARGC1A,CAMK2N2,SLC44A1,NDRG4" MicroRNA hsa-miR-151a-5p:Functional MTI Functional MTI miRTarbase 2.24E-03 1.00E+00 2.56E-03 2.36E-02 9 79 "ARHGDIA,BCL7A,CRMP1,E2F6,EIF4G2,GPER1,RFX2,CAMTA2,SPIRE1" MicroRNA hsa-miR-2053:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-03 1.00E+00 2.56E-03 2.36E-02 9 79 "XKR4,SEMA3D,EIF5,STARD3NL,NCALD,TUBA1B,SARAF,HLF,KCNN3" MicroRNA hsa-miR-596:Functional MTI Functional MTI miRTarbase 2.34E-03 1.00E+00 2.67E-03 2.46E-02 7 51 "TXNDC16,FBXL5,VTI1B,ATP13A4,POLL,TRIM68,RXRA" MicroRNA hsa-miR-631:Functional MTI Functional MTI miRTarbase 2.34E-03 1.00E+00 2.67E-03 2.46E-02 7 51 "SFMBT2,LRWD1,SYNCRIP,SYTL4,MAT2A,KITLG,WBP2" MicroRNA hsa-miR-516a-3p:Functional MTI Functional MTI miRTarbase 2.37E-03 1.00E+00 2.71E-03 2.49E-02 10 95 "LURAP1,LRRFIP1,TM9SF4,FKTN,LILRA2,SHISAL1,NCOA7,PSAT1,HSPA4L,GORASP1" MicroRNA hsa-miR-6782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-03 1.00E+00 2.71E-03 2.49E-02 10 95 "MTA3,MARCH4,IP6K1,POLL,PLEC,SETD5,SP2,CAMTA2,SEPT8,USP22" MicroRNA hsa-miR-550a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-03 1.00E+00 2.71E-03 2.49E-02 10 95 "CLK4,STX16,CBS,YTHDC1,HSPA12B,CPEB4,SOX11,UNC5B,ZNF70,ZNF154" MicroRNA hsa-miR-6757-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-03 1.00E+00 2.71E-03 2.50E-02 8 65 "TMEM184B,NCOR2,SPATA2,GOLGA7,ING4,FAM49B,ZNF491,PPARA" MicroRNA hsa-miR-1306-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.61E-03 1.00E+00 2.98E-03 2.74E-02 16 199 "RNF157,SORCS2,RNF14,MED12L,CPLX2,CRCP,METTL21A,KCNN1,SAMD5,ALDH1L2,TMOD2,FITM2,MAPKBP1,KLHL7,ALG1,RNF170" MicroRNA hsa-miR-889-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.99E-03 2.75E-02 7 52 "NCOA1,NDST3,KIAA1958,MBNL1,PEX2,KCNIP3,ARC" MicroRNA hsa-miR-4684-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.99E-03 2.75E-02 7 52 "TRMT9B,FOXN3,YAF2,KAT7,PDE3A,TUBB2A,SLC30A4" MicroRNA hsa-miR-600:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.99E-03 2.75E-02 7 52 "TRMT9B,SYNCRIP,HLF,C2orf72,NEXMIF,P2RY1,GAN" MicroRNA "GGCAGAC,MIR-346:MSigDB" "GGCAGAC,MIR-346:MSigDB" MSigDB 2.64E-03 1.00E+00 3.01E-03 2.77E-02 6 39 "OGT,AFF2,LRRTM1,MBNL1,KCTD15,CCDC136" MicroRNA hsa-miR-1909-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-03 1.00E+00 3.01E-03 2.77E-02 6 39 "CBR1,QKI,GPT2,SH3TC2,SEC31A,FBXW11" MicroRNA hsa-miR-3142:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-03 1.00E+00 3.01E-03 2.77E-02 6 39 "IP6K1,NEU3,CSRNP3,ADAMTS17,DOCK9,ZNF74" MicroRNA hsa-miR-577:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-03 1.00E+00 3.01E-03 2.77E-02 12 129 "SEMA7A,CNN3,AKAP12,MMADHC,TNRC6A,ZFYVE21,KCTD15,SH3TC2,SLC25A36,PGBD4,TAL1,EVI5" MicroRNA hsa-miR-633:Functional MTI Functional MTI miRTarbase 2.66E-03 1.00E+00 3.03E-03 2.79E-02 9 81 "PRC1,CNN3,PREPL,DLC1,ANKFY1,MMADHC,LRP12,KANK1,ZDHHC20" MicroRNA hsa-miR-1294:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.74E-03 1.00E+00 3.13E-03 2.88E-02 11 113 "CFL2,ZNF385A,EDN1,POLL,NUCB2,DIRAS2,RDX,C12orf49,SP2,KIAA0930,CBX5" MicroRNA hsa-miR-4433b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-03 1.00E+00 3.15E-03 2.90E-02 10 97 "CS,GRB10,PACSIN2,CHIC1,PLEC,SEMA6D,FBXW11,USP22,CYB561A3,RPL7L1" MicroRNA hsa-miR-611:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-03 1.00E+00 3.20E-03 2.94E-02 4 17 "BCL7A,TM9SF4,RFX2,ZNF74" MicroRNA "ATGCACG,MIR-517B:MSigDB" "ATGCACG,MIR-517B:MSigDB" MSigDB 2.81E-03 1.00E+00 3.20E-03 2.94E-02 4 17 "CABP7,CAMK2G,MEIS2,PRDM8" MicroRNA hsa-miR-1203:PITA hsa-miR-1203:PITA_TOP PITA 2.81E-03 1.00E+00 3.20E-03 2.94E-02 4 17 "PPFIA3,CAMK2N2,NFIX,SOX11" MicroRNA hsa-miR-886-3p:PITA hsa-miR-886-3p:PITA_TOP PITA 2.81E-03 1.00E+00 3.20E-03 2.94E-02 4 17 "MARK4,NFIX,NLGN3,THRA" MicroRNA hsa-miR-1537-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-03 1.00E+00 3.20E-03 2.94E-02 4 17 "IL6R,INPP5B,SLC11A2,ZDHHC20" MicroRNA hsa-miR-3184-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.88E-03 1.00E+00 3.28E-03 3.02E-02 8 67 "ZNF555,DBT,ZBED3,GATM,EXD2,APOM,SMUG1,ZNF24" MicroRNA hsa-miR-4653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.88E-03 1.00E+00 3.28E-03 3.02E-02 8 67 "ARHGDIA,EIF1,TRAF3IP2,GLUL,RAB40B,MAT2A,FAM161B,AGTPBP1" MicroRNA hsa-miR-4470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-03 1.00E+00 3.29E-03 3.03E-02 9 82 "DPY19L3,CTH,PLEKHA1,FUT10,NPTX1,RAP1GDS1,REV3L,RGMB,EVI5" MicroRNA hsa-miR-4499:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-03 1.00E+00 3.29E-03 3.03E-02 9 82 "ZC3H11A,ZBED3,SESN1,CIT,ATP8B4,SEPT8,VSNL1,WNK3,FXR1" MicroRNA hsa-miR-4506:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.92E-03 1.00E+00 3.33E-03 3.06E-02 7 53 "CSNK1E,USP6NL,ERBB2,SLC25A36,KIAA0895L,SARS,SEMA6D" MicroRNA hsa-miR-224-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-03 1.00E+00 3.34E-03 3.08E-02 11 114 "LDHD,EVI5L,CPS1,FEM1B,DCTN4,SCML2,CCSER2,FIGN,LHPP,DHX33,NETO2" MicroRNA hsa-miR-7845-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-03 1.00E+00 3.39E-03 3.12E-02 10 98 "ARHGEF2,TOGARAM2,EIF4G1,ERBB2,RAB30,AGFG1,GPR137C,SLC37A2,NACC2,UBTF" MicroRNA hsa-miR-1245b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-03 1.00E+00 3.42E-03 3.15E-02 6 40 "IP6K1,NEU3,CSRNP3,ADAMTS17,DOCK9,ZNF74" MicroRNA hsa-miR-708-3p:Functional MTI Functional MTI miRTarbase 3.01E-03 1.00E+00 3.42E-03 3.15E-02 6 40 "PSAT1,COPZ1,SH3BP2,SEPT8,ASXL3,SGK3" MicroRNA hsa-miR-182-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-03 1.00E+00 3.42E-03 3.15E-02 6 40 "MYADM,STAMBP,SCIN,FBXW7,ZC4H2,HPS4" MicroRNA hsa-miR-146a-5p:Functional MTI Functional MTI miRTarbase 3.02E-03 1.00E+00 3.43E-03 3.16E-02 16 202 "OSBPL1A,NUMB,NSL1,EGFR,ERBB4,MRPL10,COPS8,KDM2B,L1CAM,MPP2,MYO6,KCTD15,ROBO1,ELP2,SPP1,TLR4" MicroRNA hsa-miR-3529-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.14E-03 1.00E+00 3.57E-03 3.29E-02 9 83 "SLC2A11,DNAL1,EDN1,TUBD1,POLL,TDRKH,DDX19B,MTRF1L,GDPD1" MicroRNA hsa-miR-4255:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.14E-03 1.00E+00 3.57E-03 3.29E-02 9 83 "CDC14B,ZNF555,CNN3,CPS1,SOCS5,SUCO,RAB30,FICD,MTCH1" MicroRNA hsa-miR-4749-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.14E-03 1.00E+00 3.57E-03 3.29E-02 9 83 "LTBP4,PDZD4,CACNA1A,TMEM184B,DISC1,NFIX,C12orf49,SBF1,PEX26" MicroRNA hsa-miR-522-3p:Non-Functional MTI Non-Functional MTI miRTarbase 3.14E-03 1.00E+00 3.57E-03 3.29E-02 11 115 "LDHD,EVI5L,CPS1,FEM1B,DCTN4,SCML2,CCSER2,FIGN,LHPP,DHX33,NETO2" MicroRNA hsa-miR-6868-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-03 1.00E+00 3.58E-03 3.30E-02 8 68 "C6orf89,GOLGA7,NLE1,DPF2,COPZ1,SLC6A8,MYH15,FAM182B" MicroRNA hsa-miR-128-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-03 1.00E+00 3.58E-03 3.30E-02 8 68 "TOM1,DOT1L,SEPT9,NFIX,LIMS2,MPRIP,STX1A,DNMBP" MicroRNA hsa-miR-4749-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-03 1.00E+00 3.58E-03 3.30E-02 8 68 "MRO,METTL21A,CYP27C1,VWA2,NACC2,RPRM,MGAT5B,DPYSL5" MicroRNA hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 3.16E-03 1.00E+00 3.58E-03 3.30E-02 8 68 "COPB2,KIAA0040,SYNCRIP,STMN1,MAT2A,PPP2R5E,GTDC1,CCDC88A" MicroRNA hsa-miR-4797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-03 1.00E+00 3.58E-03 3.30E-02 8 68 "ZNF583,COL4A5,LRIG1,GABRG1,FITM2,RAP1GDS1,CXXC4,ZNF24" MicroRNA hsa-miR-6732-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.21E-03 1.00E+00 3.64E-03 3.35E-02 10 99 "EVI5L,GRIN2D,KCNK3,PKM,KANSL1,SHMT2,NMNAT2,ERC1,THRA,RICTOR" MicroRNA hsa-miR-371b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-03 1.00E+00 3.69E-03 3.40E-02 7 54 "ADD1,FLT1,AFF1,XRRA1,ADAM22,ZC3H12B,TMEM231" MicroRNA hsa-miR-4686:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-03 1.00E+00 3.69E-03 3.40E-02 7 54 "HDAC4,FER,IRF8,MKLN1,MYCN,CEP97,VLDLR" MicroRNA "GGATCCG,MIR-127:MSigDB" "GGATCCG,MIR-127:MSigDB" MSigDB 3.39E-03 1.00E+00 3.84E-03 3.54E-02 3 9 "SEPT7,RIMS4,BCAS3" MicroRNA hsa-miR-509-3p:Functional MTI Functional MTI miRTarbase 3.42E-03 1.00E+00 3.87E-03 3.56E-02 6 41 "ARHGEF7,NR1D2,NTRK3,FITM2,RAD51D,CBX5" MicroRNA hsa-miR-6834-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-03 1.00E+00 3.87E-03 3.56E-02 6 41 "PAX6,ARMH4,CLIP1,PRRC2C,WBP2,ZNF24" MicroRNA hsa-miR-5002-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-03 1.00E+00 3.87E-03 3.56E-02 6 41 "QKI,PLXNA4,RCAN1,EMID1,FAM124A,WIPF1" MicroRNA hsa-miR-3180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-03 1.00E+00 3.91E-03 3.60E-02 10 100 "AMH,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,FXYD1,SBF1,WSCD1" MicroRNA hsa-miR-3180:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-03 1.00E+00 3.91E-03 3.60E-02 10 100 "AMH,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,FXYD1,SBF1,WSCD1" MicroRNA hsa-miR-942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-03 1.00E+00 3.92E-03 3.61E-02 8 69 "TAOK1,APBB2,ARHGEF2,CTH,LILRA2,ZBTB45,PURG,STX1B" MicroRNA hsa-miR-520f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-03 1.00E+00 3.92E-03 3.61E-02 8 69 "ADD1,SORCS2,MRNIP,ZC3H13,CRTC1,DHX33,PPP1R3F,PLSCR4" MicroRNA hsa-miR-6839-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-03 1.00E+00 3.92E-03 3.61E-02 8 69 "LCORL,CSNK1E,DLC1,GPR155,NFYA,MTRF1L,CNNM2,PARD3" MicroRNA hsa-miR-219b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-03 1.00E+00 3.95E-03 3.64E-02 16 205 "APAF1,PTBP2,TPP1,SUMF2,DNAL1,RASA4,ZNF585B,ZNF589,FAM107A,MXI1,ZNF844,SNX22,PEG10,MCF2L2,SSBP2,PARP11" MicroRNA hsa-miR-184:TargetScan hsa-miR-184 TargetScan 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "EPB41L5,NCOR2,DBNL,CRTC1" MicroRNA hsa-miR-1281:PITA hsa-miR-1281:PITA_TOP PITA 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "CABP1,AGAP3,TNRC6A,PTPRD" MicroRNA "CTACTAG,MIR-325:MSigDB" "CTACTAG,MIR-325:MSigDB" MSigDB 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "CELF1,TMCC1,ANKRD28,RIMBP2" MicroRNA hsa-miR-652:PITA hsa-miR-652:PITA_TOP PITA 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "AKAP6,GABRB3,TNRC6A,ZFAND5" MicroRNA hsa-miR-8078:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "GREB1,WDPCP,CAMKK2,SMUG1" MicroRNA hsa-miR-933:PITA hsa-miR-933:PITA_TOP PITA 3.51E-03 1.00E+00 3.96E-03 3.65E-02 4 18 "MAP4K4,ZNF521,ZFHX4,POLR3H" MicroRNA hsa-miR-6746-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.58E-03 1.00E+00 4.05E-03 3.73E-02 5 29 "LETMD1,METTL21A,LAMP2,RADIL,PBLD" MicroRNA hsa-miR-635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-03 1.00E+00 4.08E-03 3.76E-02 7 55 "SEMA7A,ARHGDIA,SUMF2,EPB41,CELF1,CNNM2,ZKSCAN3" MicroRNA hsa-miR-6740-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-03 1.00E+00 4.08E-03 3.76E-02 7 55 "DYNLL1,DLC1,ZMAT1,MALT1,GLI2,SLC6A8,NMNAT2" MicroRNA hsa-miR-592:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-03 1.00E+00 4.08E-03 3.76E-02 7 55 "AKAP12,FOXO3,HS6ST3,BTBD3,NMNAT2,PRRC2C,WRN" MicroRNA hsa-miR-200b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-03 1.00E+00 4.08E-03 3.76E-02 7 55 "PROM1,CPS1,CS,OLA1,ZMAT4,CLIP1,ZNF138" MicroRNA hsa-miR-6781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-03 1.00E+00 4.19E-03 3.85E-02 10 101 "RNF150,ARSE,AP1M1,ELMSAN1,FLYWCH1,NXPH3,ATXN2,ZNF621,CBX5,HNRNPA3" MicroRNA hsa-miR-6816-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-03 1.00E+00 4.19E-03 3.85E-02 10 101 "AMH,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,FXYD1,SBF1,WSCD1" MicroRNA hsa-miR-2682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-03 1.00E+00 4.19E-03 3.85E-02 10 101 "RNF150,ARSE,AP1M1,ELMSAN1,FLYWCH1,NXPH3,ATXN2,ZNF621,CBX5,HNRNPA3" MicroRNA hsa-miR-5688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.77E-03 1.00E+00 4.25E-03 3.92E-02 14 170 "TMEFF1,MYADM,DGKB,DLC1,IL6R,MSANTD3-TMEFF1,NCAM2,OCRL,PRRT2,ZNF354C,TRIM67,MPRIP,ARL10,ADAMTS9" MicroRNA hsa-miR-654-3p:Functional MTI Functional MTI miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "ZNF578,PTBP2,EXOG,GABRG1,PDPK1,PKIA,ZMAT3,ZNF610" MicroRNA hsa-miR-1266-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "CCNT1,LRRFIP1,BAG4,RCAN1,DLC1,KIAA1958,SLC2A5,EXOC7" MicroRNA hsa-miR-4680-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "ERBB2,NEGR1,LSAMP,N6AMT1,PDPK1,PEX2,FNBP1,TROVE2" MicroRNA hsa-miR-876-3p:Functional MTI Functional MTI miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "NDST3,ENTPD4,RUBCN,ELN,MTRF1L,RBBP6,ROBO1,PEG10" MicroRNA hsa-miR-675-5p:Functional MTI Functional MTI miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "ESYT2,DIS3L,AKAP5,HDAC4,MITF,FITM2,INAVA,NMNAT2" MicroRNA hsa-miR-3144-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.79E-03 1.00E+00 4.27E-03 3.93E-02 8 70 "TRMT9B,TBPL1,SEPT9,SESN1,CELF5,NFIX,PKM,POLR2F" MicroRNA hsa-miR-151b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-03 1.00E+00 4.35E-03 4.01E-02 6 42 "ARHGDIA,BCL7A,CRMP1,GPER1,RFX2,CAMTA2" MicroRNA hsa-miR-3921:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-03 1.00E+00 4.50E-03 4.14E-02 9 86 "PPP1R16B,ERBB2,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ARL10,ZNF708" MicroRNA hsa-miR-7159-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-03 1.00E+00 4.50E-03 4.14E-02 9 86 "KIAA0319,DDX46,GABRG2,TRAPPC13,SALL1,MYO18A,KIF13A,ERBIN,KIAA0930" MicroRNA hsa-miR-3136-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-03 1.00E+00 4.50E-03 4.15E-02 7 56 "DYNLL1,CRY2,MSANTD2,SHMT2,BTBD3,ZC3H4,ALG1" MicroRNA hsa-miR-3117-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-03 1.00E+00 4.50E-03 4.15E-02 7 56 "KIAA0408,C8orf37,SMC2,KCNB1,STMN1,ZHX3,GAN" MicroRNA hsa-miR-7155-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-03 1.00E+00 4.50E-03 4.15E-02 7 56 "DYNLL1,CRY2,MSANTD2,SHMT2,BTBD3,ZC3H4,ALG1" MicroRNA hsa-miR-3935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-03 1.00E+00 4.50E-03 4.15E-02 7 56 "BACH1,SRSF11,BAG4,AKAP12,TNRC6A,ZNF678,CHD9" MicroRNA hsa-miR-146b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-03 1.00E+00 4.50E-03 4.15E-02 7 56 "CPS1,FAM107A,MAT2A,TRIM67,CPEB4,SZT2,GDPD5" MicroRNA hsa-miR-381-3p:Functional MTI Functional MTI miRTarbase 4.06E-03 1.00E+00 4.57E-03 4.21E-02 12 136 "SPAG9,COPB2,CLTC,HDAC4,SEMA4D,ZNF181,ZNF546,MBNL1,MID1,PRKCB,CNKSR2,SLC6A8" MicroRNA hsa-miR-4503:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.13E-03 1.00E+00 4.65E-03 4.28E-02 8 71 "SPOP,VAT1L,CLTB,IP6K1,LIMS1,SAMD5,MYCN,PARD3" MicroRNA hsa-miR-4760-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.13E-03 1.00E+00 4.65E-03 4.28E-02 8 71 "BARD1,CALM1,HIPK3,SLC35G1,KCNQ3,LIFR,PDE4D,MAGEL2" MicroRNA hsa-miR-129-2-3p:Functional MTI Functional MTI miRTarbase 4.13E-03 1.00E+00 4.65E-03 4.28E-02 8 71 "NUMBL,RGS6,GAPVD1,DUSP9,E2F5,CACFD1,KCNB1,NPTX2" MicroRNA hsa-miR-4325:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-03 1.00E+00 4.69E-03 4.31E-02 13 154 "JAZF1,CLOCK,MRO,DLC1,DBF4,AGBL5,PDE4D,ZFYVE21,TATDN3,FAM126B,TROVE2,PLCB1,HNRNPA3" MicroRNA hsa-miR-487b:PITA hsa-miR-487b:PITA_TOP PITA 4.17E-03 1.00E+00 4.69E-03 4.31E-02 5 30 "SNAP91,RNF165,CLIP1,KAT6B,ZIC1" MicroRNA hsa-miR-3196:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.27E-03 1.00E+00 4.80E-03 4.42E-02 10 103 "AMH,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,FXYD1,SBF1,WSCD1" MicroRNA hsa-miR-4653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 9 87 "PPP1R16B,ERBB2,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ARL10,ZNF708" MicroRNA hsa-miR-1914-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 9 87 "CACNA1B,DBN1,FKTN,POLL,AFF1,SH3KBP1,GLDN,CLSTN2,ZNF138" MicroRNA hsa-miR-6835-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 9 87 "DBT,DOT1L,NLE1,KANSL1,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1" MicroRNA hsa-miR-5091:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 4 19 "SCARB1,SLC43A2,CHIC1,SSBP2" MicroRNA hsa-miR-4304:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 4 19 "LIFR,ATF7IP,AMZ1,URM1" MicroRNA hsa-miR-6727-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 4 19 "AMH,PRX,RGS6,SEC16A" MicroRNA hsa-miR-3131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-03 1.00E+00 4.84E-03 4.46E-02 4 19 "BCL7A,TM9SF4,RFX2,ZNF74" MicroRNA hsa-miR-376b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-03 1.00E+00 4.88E-03 4.50E-02 6 43 "CA8,CD86,MKLN1,CEP97,PCDHA6,FRYL" MicroRNA hsa-miR-376c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-03 1.00E+00 4.88E-03 4.50E-02 6 43 "CA8,CD86,MKLN1,CEP97,PCDHA6,FRYL" MicroRNA "TCTAGAG,MIR-517:MSigDB" "TCTAGAG,MIR-517:MSigDB" MSigDB 4.36E-03 1.00E+00 4.88E-03 4.50E-02 6 43 "MAGED1,CS,MSTN,KCND2,ING3,SNAP25" MicroRNA hsa-miR-4509:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-03 1.00E+00 4.96E-03 4.56E-02 7 57 "SLC24A4,TNRC6C,FRY,SARAF,GCK,CLIP1,ZC3H13" MicroRNA hsa-miR-6499-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-03 1.00E+00 4.96E-03 4.56E-02 7 57 "PTCHD1,CASKIN1,TXNDC16,TRMT9B,CPLX1,BVES,ZKSCAN3" MicroRNA hsa-miR-128-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-03 1.00E+00 5.05E-03 4.65E-02 8 72 "TOM1,DOT1L,SEPT9,NFIX,LIMS2,MPRIP,STX1A,DNMBP" MicroRNA hsa-miR-876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-03 1.00E+00 5.05E-03 4.65E-02 8 72 "TAOK1,ABCG2,PYGO1,CBX1,MAT2A,P2RX7,P2RY1,ALG1" MicroRNA hsa-miR-6802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-03 1.00E+00 5.05E-03 4.65E-02 8 72 "C6orf89,BARD1,ZNF445,GAPVD1,GABRB3,OLA1,FAM126B,SP2" MicroRNA hsa-miR-6768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.58E-03 1.00E+00 5.12E-03 4.72E-02 10 104 "TAOK1,CLCN3,CRY2,RUBCN,CDON,KCNN3,OCRL,P2RY1,SLC25A36,INAVA" MicroRNA hsa-miR-3186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.72E-03 1.00E+00 5.28E-03 4.86E-02 3 10 "LRFN1,CACNA1B,TPPP" MicroRNA hsa-miR-3618:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.83E-03 1.00E+00 5.40E-03 4.97E-02 5 31 "PDE4DIP,PUM1,KLHL3,FREM1,FAM126B" MicroRNA hsa-miR-602:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.83E-03 1.00E+00 5.40E-03 4.97E-02 5 31 "TMEM132B,PDZD4,PPFIA3,DNAL1,MYO16" MicroRNA hsa-miR-4454:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.88E-03 1.00E+00 5.45E-03 5.02E-02 7 58 "ENTPD4,MYADM,CRCP,KCNN1,PIK3C2A,GDPD1,UGT8" MicroRNA hsa-miR-491-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.88E-03 1.00E+00 5.45E-03 5.02E-02 7 58 "PTCH2,ST6GALNAC3,GRM8,ZNF678,MBNL1,ABCB1,CPEB4" MicroRNA "CAAGGAT,MIR-362:MSigDB" "CAAGGAT,MIR-362:MSigDB" MSigDB 4.88E-03 1.00E+00 5.45E-03 5.02E-02 7 58 "CAPN3,RIMS4,SPATA2,RAPGEF6,STRN3,CPEB4,TCEA1" MicroRNA hsa-miR-4751:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.88E-03 1.00E+00 5.45E-03 5.02E-02 7 58 "CASKIN1,SCML2,ANKFY1,KSR2,ELP2,ZC3H4,TNS1" MicroRNA hsa-miR-3189-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.90E-03 1.00E+00 5.48E-03 5.04E-02 8 73 "ARHGEF25,CCNT1,DNAL1,CELF1,ZNF568,STX1B,POGZ,NACC2" MicroRNA hsa-miR-4539:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.90E-03 1.00E+00 5.48E-03 5.04E-02 8 73 "CCAR2,ABCG2,TMEM184B,PYGO1,SPATA2,PRKACB,KANSL3,ZC4H2" MicroRNA hsa-miR-4712-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.90E-03 1.00E+00 5.48E-03 5.04E-02 8 73 "OSBPL3,IST1,MSANTD4,MMP16,OLA1,PPP2R5E,TRIM67,RPL7L1" MicroRNA hsa-miR-4706:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.02E-03 1.00E+00 5.60E-03 5.16E-02 9 89 "LTBP4,PDZD4,CACNA1A,TMEM184B,DISC1,NFIX,C12orf49,SBF1,PEX26" MicroRNA hsa-miR-2392:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.12E-03 1.00E+00 5.72E-03 5.27E-02 12 140 "XKR4,TAOK1,PPP1R16B,WDPCP,ANKRD46,TRAF3IP2,TJAP1,MTMR10,SETD5,MRAS,TUBB2A,MSRB3" MicroRNA hsa-miR-3176:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-03 1.00E+00 5.84E-03 5.38E-02 10 106 "DBT,COQ7,CELF1,ZNF274,RAB30,FICD,HAS2,PKM,SP4,USP22" MicroRNA hsa-miR-566:PITA hsa-miR-566:PITA_TOP PITA 5.24E-03 1.00E+00 5.85E-03 5.39E-02 4 20 "CABP1,EIF1,GABRB3,SMG6" MicroRNA hsa-miR-525-3p:Functional MTI Functional MTI miRTarbase 5.24E-03 1.00E+00 5.85E-03 5.39E-02 4 20 "PRX,ARRB1,ZBTB45,HSD11B1L" MicroRNA hsa-miR-585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-03 1.00E+00 5.85E-03 5.39E-02 4 20 "CDC25B,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-508-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-03 1.00E+00 5.98E-03 5.51E-02 7 59 "PUM1,RGS17,RAB30,RASSF8,MBNL1,ROBO1,SATB2" MicroRNA hsa-miR-1910-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-03 1.00E+00 5.98E-03 5.51E-02 7 59 "USP37,DNAH17,ZNF583,TNK2,MTHFD2,PRRC2B,JPH3" MicroRNA hsa-miR-4417:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-03 1.00E+00 5.98E-03 5.51E-02 7 59 "ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SATB1,SHMT2" MicroRNA hsa-miR-4711-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-03 1.00E+00 5.98E-03 5.51E-02 7 59 "INSYN2B,SLC2A11,FCF1,ZNF274,USP47,SALL1,FNDC3A" MicroRNA hsa-miR-4709-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.40E-03 1.00E+00 6.02E-03 5.54E-02 9 90 "TNRC6C,ARHGAP22,KIAA0040,E2F6,IDH3B,KCNN3,PDPK1,TRIM16L,PARP11" MicroRNA hsa-miR-1231:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.48E-03 1.00E+00 6.10E-03 5.62E-02 6 45 "CACNA1A,FOXF2,POLL,THYN1,AMBRA1,FAIM2" MicroRNA hsa-miR-492:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.48E-03 1.00E+00 6.10E-03 5.62E-02 6 45 "BID,GDA,GAPVD1,MAT2A,ST6GAL1,DHX33" MicroRNA hsa-miR-422a:Non-Functional MTI Non-Functional MTI miRTarbase 5.48E-03 1.00E+00 6.10E-03 5.62E-02 6 45 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CELF4" MicroRNA hsa-miR-621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-03 1.00E+00 6.18E-03 5.69E-02 5 32 "TRMT9B,TOGARAM2,FOXO3,MIER3,ACTR3B" MicroRNA hsa-miR-181c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-03 1.00E+00 6.18E-03 5.69E-02 5 32 "HIPK3,TMEM175,ADAMTS13,KCNN3,GPR137C" MicroRNA hsa-miR-24-2-5p:Functional MTI Functional MTI miRTarbase 5.55E-03 1.00E+00 6.18E-03 5.69E-02 5 32 "ELOVL5,NFIX,TMEM231,SP2,DHX33" MicroRNA hsa-miR-6837-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-03 1.00E+00 6.21E-03 5.71E-02 11 124 "MARCH4,C6orf89,BAIAP3,KLHL3,CELF1,NSG1,NFIX,RNH1,HES6,MAPKBP1,PCDHA6" MicroRNA hsa-miR-4666a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.59E-03 1.00E+00 6.22E-03 5.73E-02 10 107 "SPAG9,COPB2,TMTC1,RCAN2,SEMA4D,ZNF181,ZNF546,MBNL1,CNKSR2,TNS1" MicroRNA hsa-miR-29b-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-03 1.00E+00 6.42E-03 5.91E-02 8 75 "AKAP12,GPR155,MAT2A,KITLG,MMP16,EPB41L4B,ZNF430,SNAP25" MicroRNA hsa-miR-4424:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-03 1.00E+00 6.42E-03 5.91E-02 8 75 "HACE1,STARD3NL,SLC35G1,GRAMD1C,FAM126B,TRPS1,RPL7L1,USP1" MicroRNA hsa-miR-5702:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-03 1.00E+00 6.42E-03 5.91E-02 8 75 "OGT,UBXN2A,SLC12A6,ANKRD46,NKD1,KCNN1,HSPA4L,SPART" MicroRNA hsa-miR-4675:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-03 1.00E+00 6.42E-03 5.91E-02 8 75 "DBN1,ABCC5,CELF1,PKM,PRRT2,SBF1,PEX26,THRA" MicroRNA hsa-miR-3918:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-03 1.00E+00 6.42E-03 5.91E-02 8 75 "C6orf89,PRX,LDLRAD4,SEC16A,NSG1,CSDC2,KPNA5,NFIX" MicroRNA hsa-miR-550a-3-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-03 1.00E+00 6.45E-03 5.93E-02 9 91 "CLK4,STX16,CBS,YTHDC1,HSPA12B,SOX11,UNC5B,ZNF70,ZNF154" MicroRNA hsa-miR-452-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-03 1.00E+00 6.45E-03 5.93E-02 9 91 "CDC14B,PDE4DIP,SEC24B,PCDH17,SH3TC2,ATXN7,LIMCH1,NSFL1C,ZDHHC20" MicroRNA hsa-miR-1271-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-03 1.00E+00 6.45E-03 5.93E-02 9 91 "CLK4,STX16,CBS,YTHDC1,HSPA12B,SOX11,UNC5B,ZNF70,ZNF154" MicroRNA hsa-miR-92a-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-03 1.00E+00 6.45E-03 5.93E-02 9 91 "IQGAP2,TJAP1,FBXW7,ZFP30,UNC5B,CBX5,DPYSL5,CIAPIN1,GAN" MicroRNA hsa-miR-5003-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.89E-03 1.00E+00 6.54E-03 6.02E-02 7 60 "ATP1A3,RAB39B,NPTX1,SEMA6D,CLASP1,ZNF106,TOM1L2" MicroRNA hsa-miR-6779-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.89E-03 1.00E+00 6.54E-03 6.02E-02 7 60 "EPS15L1,GAPVD1,TBC1D5,EPB41,NCKAP1L,SZT2,TMEM63C" MicroRNA hsa-miR-5196-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.92E-03 1.00E+00 6.57E-03 6.05E-02 11 125 "TAOK1,CFAP410,KIF26A,PCDH17,ZMAT4,ALG9,SEMA6D,BDP1,ERC1,ELOVL4,ZNF195" MicroRNA hsa-miR-4685-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.92E-03 1.00E+00 6.57E-03 6.05E-02 11 125 "MARCH4,C6orf89,BAIAP3,KLHL3,CELF1,NSG1,NFIX,RNH1,HES6,MAPKBP1,PCDHA6" MicroRNA hsa-miR-4747-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.11E-03 1.00E+00 6.77E-03 6.24E-02 6 46 "RGS6,ZBTB45,IBA57,XRN1,RBBP6,PTGR2" MicroRNA hsa-miR-6724-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.11E-03 1.00E+00 6.77E-03 6.24E-02 6 46 "SUMF2,ADAMTS13,ZDHHC15,ZDHHC8,ZKSCAN3,SP2" MicroRNA hsa-miR-6773-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.11E-03 1.00E+00 6.77E-03 6.24E-02 6 46 "SUMF2,ADAMTS13,ZDHHC15,ZDHHC8,ZKSCAN3,SP2" MicroRNA hsa-miR-585-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.11E-03 1.00E+00 6.77E-03 6.24E-02 6 46 "TXNDC16,FEM1B,GOLGA7,EIF4G2,PFKFB2,SMARCC2" MicroRNA hsa-miR-495-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.23E-03 1.00E+00 6.91E-03 6.36E-02 9 92 "CALM1,RTTN,YAF2,CELF1,MTHFD2,GLUL,CCSER2,CARF,PLSCR4" MicroRNA "GTCTACC,MIR-379:MSigDB" "GTCTACC,MIR-379:MSigDB" MSigDB 6.29E-03 1.00E+00 6.97E-03 6.42E-02 4 21 "EIF4G2,UBE2E3,CACFD1,ADGRL3" MicroRNA hsa-miR-548ao-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-03 1.00E+00 6.97E-03 6.42E-02 4 21 "FICD,ZNF844,ASAP3,GAN" MicroRNA hsa-miR-139-3p:PITA hsa-miR-139-3p:PITA_TOP PITA 6.29E-03 1.00E+00 6.97E-03 6.42E-02 4 21 "MSI1,FUZ,CAMTA2,POLR3H" MicroRNA hsa-miR-658:PITA hsa-miR-658:PITA_TOP PITA 6.29E-03 1.00E+00 6.97E-03 6.42E-02 4 21 "LRFN1,CABP1,PPP1R16B,DCBLD1" MicroRNA hsa-miR-423-3p:TargetScan hsa-miR-423-3p TargetScan 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "CINP,MYO9A,ARFGAP1" MicroRNA "AACGGTT,MIR-451:MSigDB" "AACGGTT,MIR-451:MSigDB" MSigDB 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "OGT,MINDY2,EMSY" MicroRNA hsa-miR-615-3p:TargetScan hsa-miR-615-3p TargetScan 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "MYLK2,MAPT,ARFGAP1" MicroRNA hsa-miR-5705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "PRRC2B,CHIC1,TFIP11" MicroRNA hsa-miR-517b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "DBN1,NACC2,USP1" MicroRNA hsa-miR-937-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.31E-03 1.00E+00 6.98E-03 6.43E-02 3 11 "DCAF8,GLUL,CAMK2N2" MicroRNA hsa-miR-5092:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.35E-03 1.00E+00 7.03E-03 6.47E-02 5 33 "HEYL,GTF2IRD2,CHIC1,SMIM11A,OGG1" MicroRNA hsa-miR-6755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.35E-03 1.00E+00 7.03E-03 6.47E-02 5 33 "SOCS6,WDPCP,RDX,SLC22A4,POGZ" MicroRNA hsa-miR-138-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "AS3MT,FZD9,TAOK1,FEM1B,MRVI1,FREM1,FAM126B" MicroRNA hsa-miR-518f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-523-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-519b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-526a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-519c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-518d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-518e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-519a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-520c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-03 1.00E+00 7.12E-03 6.55E-02 7 61 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-4276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.68E-03 1.00E+00 7.37E-03 6.79E-02 9 93 "ABCD2,IP6K1,RCAN1,TNRC6A,NPTX1,BTBD3,CDK19,SPART,FXR1" MicroRNA hsa-miR-874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.76E-03 1.00E+00 7.46E-03 6.87E-02 8 77 "ATP2A2,RGS6,CRCP,FAM107A,MAPT,TRIM67,CPEB4,GDPD5" MicroRNA hsa-miR-4260:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.76E-03 1.00E+00 7.46E-03 6.87E-02 8 77 "GLI2,TNRC6A,PRRC2B,ELOVL5,SCIN,MSI1,MAPK10,NMNAT2" MicroRNA hsa-miR-5572:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.76E-03 1.00E+00 7.46E-03 6.87E-02 8 77 "PDLIM5,GLI2,TNRC6A,PRRC2B,SCIN,MSI1,MAPK10,NMNAT2" MicroRNA hsa-miR-210-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-03 1.00E+00 7.49E-03 6.89E-02 6 47 "XKR4,LONRF2,MRO,MSANTD4,SCN7A,NACC2" MicroRNA hsa-miR-7112-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-03 1.00E+00 7.49E-03 6.89E-02 6 47 "INSYN2B,LONRF2,ANKFY1,ZNF274,USP47,SALL1" MicroRNA hsa-miR-7158-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-03 1.00E+00 7.49E-03 6.89E-02 6 47 "CFL2,UBXN2A,SUCO,MMP16,ZMAT3,PARD3" MicroRNA hsa-miR-3691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-03 1.00E+00 7.49E-03 6.89E-02 6 47 "CA8,CD86,MRPL10,CSPG5,NXPH3,PACSIN2" MicroRNA hsa-miR-522-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-03 1.00E+00 7.76E-03 7.15E-02 7 62 "TAOK1,CALM1,MSANTD4,TJAP1,SLC35G1,PCSK1,HPS4" MicroRNA hsa-miR-4752:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-03 1.00E+00 7.76E-03 7.15E-02 7 62 "LDHD,CA8,CD86,ZC3H11A,C8orf37,MYO18A,ZNF106" MicroRNA hsa-miR-5189-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.16E-03 1.00E+00 7.88E-03 7.26E-02 9 94 "SLC2A11,NRXN3,TOGARAM2,PITPNM3,GREB1,FLT1,ARL10,VLDLR,HPS4" MicroRNA hsa-miR-4436b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.16E-03 1.00E+00 7.88E-03 7.26E-02 9 94 "VCAN,TIAM2,HEYL,RCAN2,MIER3,SETD5,ATXN2,TUBB2A,PPP1R3F" MicroRNA hsa-miR-3186-3p:mirSVR_highEffct hsa-miR-3186-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.23E-03 1.00E+00 7.96E-03 7.33E-02 5 34 "CELF1,FERMT2,PTOV1,SNRPN,PMS2CL" MicroRNA hsa-miR-551b:mirSVR_highEffct hsa-miR-551b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.30E-03 1.00E+00 8.04E-03 7.40E-02 8 78 "LETMD1,NTRK2,PTK2,TMEM255A,NCBP3,SPART,PJA1,CRB2" MicroRNA hsa-miR-6743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.47E-03 1.00E+00 8.23E-03 7.57E-02 4 22 "ADD1,PTBP2,ZNF638,PTGR2" MicroRNA hsa-miR-128b:Functional MTI Functional MTI miRTarbase 7.51E-03 1.00E+00 8.26E-03 7.61E-02 2 4 "EGFR,AFF1" MicroRNA hsa-miR-412-5p:TargetScan hsa-miR-412-5p TargetScan 7.51E-03 1.00E+00 8.26E-03 7.61E-02 2 4 "PCDH10,FICD" MicroRNA hsa-miR-425-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-03 1.00E+00 8.28E-03 7.62E-02 6 48 "MTHFD2,PPARGC1A,FAM208A,ATMIN,ZNF28,TFIP11" MicroRNA hsa-miR-6735-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-03 1.00E+00 8.28E-03 7.62E-02 6 48 "MTHFD2,RAB30,TNRC6A,ZNF638,GNAL,FICD" MicroRNA hsa-miR-6874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-03 1.00E+00 8.28E-03 7.62E-02 6 48 "BOC,APC2,NPTX2,PEG10,NSD1,NACC2" MicroRNA hsa-miR-4640-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-03 1.00E+00 8.28E-03 7.62E-02 6 48 "ARRB1,CYBB,CHST15,KIRREL1,SCN2B,NFASC" MicroRNA hsa-miR-3670:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-03 1.00E+00 8.28E-03 7.62E-02 6 48 "CDR1,SEC24C,PITPNM3,PPP1R16B,SEPT8,STXBP4" MicroRNA hsa-miR-3690:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "APBB2,RIMS4,ANKMY1,CRCP,C2orf72,STX1B,AGTPBP1" MicroRNA hsa-miR-3134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "TUBA1B,TNRC6A,MPP2,OLA1,SLC25A36,POGZ,KAT6A" MicroRNA hsa-miR-3928-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "SRSF11,ZBED3,SOWAHA,SNX10,POLG,KANSL1,AMBRA1" MicroRNA hsa-miR-6894-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "TAOK1,USP37,PRX,ARSE,IP6K1,HSPA4L,GPRIN3" MicroRNA hsa-miR-6806-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "SRSF11,ZBED3,SOWAHA,SNX10,POLG,KANSL1,AMBRA1" MicroRNA hsa-miR-499b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.43E-03 7.77E-02 7 63 "CACNA1B,LIN54,DNAH9,MAMLD1,FEM1B,SRRM1,FIGN" MicroRNA hsa-miR-6732-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.88E-03 1.00E+00 8.66E-03 7.97E-02 11 130 "CBS,USP6NL,TMEM170A,LILRA2,MAT2A,KSR2,NCBP3,TRA2B,FAM208A,ZNF708,HPS4" MicroRNA hsa-miR-4694-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.19E-03 1.00E+00 8.98E-03 8.27E-02 5 35 "MARCH4,LDHD,DNAJB6,C8orf37,POGZ" MicroRNA hsa-miR-4787-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.19E-03 1.00E+00 8.98E-03 8.27E-02 5 35 "ARHGDIA,MYADM,MTSS1L,PKD1,SNX22" MicroRNA hsa-miR-551b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.19E-03 1.00E+00 8.98E-03 8.27E-02 3 12 "MAP4,MCMBP,STX1B" MicroRNA "TCCGTCC,MIR-184:MSigDB" "TCCGTCC,MIR-184:MSigDB" MSigDB 8.19E-03 1.00E+00 8.98E-03 8.27E-02 3 12 "EPB41L5,ATXN2L,PRKCB" MicroRNA hsa-miR-28-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-03 1.00E+00 9.12E-03 8.40E-02 6 49 "INTS2,PHF12,EIF4G2,ZFYVE21,COPZ1,TRPS1" MicroRNA hsa-miR-598:PITA hsa-miR-598:PITA_TOP PITA 8.32E-03 1.00E+00 9.12E-03 8.40E-02 6 49 "CALM1,TOX3,MN1,ZDHHC14,SNCA,TIAM1" MicroRNA hsa-miR-514b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-03 1.00E+00 9.16E-03 8.44E-02 7 64 "ZNF582,FEM1B,ANKMY1,KCNB1,ROBO2,CBX5,NR2E1" MicroRNA hsa-miR-532-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-03 1.00E+00 9.16E-03 8.44E-02 7 64 "THSD7A,MRNIP,NKD1,RBPJ,CCSER2,PIGG,EPC1" MicroRNA hsa-miR-6760-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.48E-03 1.00E+00 9.29E-03 8.56E-02 8 80 "TMEM132B,FYN,MBNL1,MAP6D1,HSPA4L,AMACR,ZNF24,HPS4" MicroRNA hsa-miR-3713:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.79E-03 1.00E+00 9.63E-03 8.87E-02 4 23 "MSANTD4,C15orf41,C2orf72,TMCC1" MicroRNA hsa-miR-1306:PITA hsa-miR-1306:PITA_TOP PITA 8.79E-03 1.00E+00 9.63E-03 8.87E-02 4 23 "MSTN,NFIX,CEP41,ERC1" MicroRNA hsa-miR-514a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.08E-03 1.00E+00 9.95E-03 9.16E-02 7 65 "ZNF582,FEM1B,ANKMY1,KCNB1,ROBO2,CBX5,NR2E1" MicroRNA hsa-miR-4781-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "LTBP4,ATP2A2,CRMP1,SNX22,UNC5B,WSCD1" MicroRNA hsa-miR-6874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "PTPRT,HSF2,MMP17,MTMR10,MAP6D1,APOM" MicroRNA hsa-miR-4799-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "CACNA2D1,GOLGA7,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-660-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "EIF1,ATP13A4,ZHX1,XRRA1,TMLHE,WNK3" MicroRNA hsa-miR-6500-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "PTPRT,HSF2,MMP17,NBL1,MTMR10,APOM" MicroRNA hsa-miR-8075:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "RNF165,MBNL1,FAM98B,SCN7A,PEAR1,TOM1L2" MicroRNA hsa-miR-5187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "ABCD2,ERBB2,N6AMT1,PEX2,KIAA0895L,FNBP1" MicroRNA hsa-miR-4633-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-03 1.00E+00 1.00E-02 9.23E-02 6 50 "PTPRT,HSF2,MMP17,NBL1,MTMR10,APOM" MicroRNA hsa-miR-24-1-5p:Functional MTI Functional MTI miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "ELOVL5,NFIX,TMEM231,SP2,DHX33" MicroRNA hsa-miR-374c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "FAM135A,HLF,MYCN,SALL1,KLHL7" MicroRNA hsa-miR-4633-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "CFL2,MRNIP,CCSER2,PIGG,CPEB4" MicroRNA hsa-miR-1225-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "CDR1,SEMA4D,ZNF678,SEMA6D,DHX33" MicroRNA hsa-miR-4529-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "E2F6,RNF165,ZIC5,FITM2,MYO18A" MicroRNA hsa-miR-135a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "CA8,SEPT7,RGS6,AMOTL2,ZNF138" MicroRNA hsa-miR-4681:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.23E-03 1.00E+00 1.01E-02 9.28E-02 5 36 "CCAR2,NEURL4,PRRC2B,MRAS,IQCE" MicroRNA hsa-miR-4794:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.29E-03 1.00E+00 1.01E-02 9.34E-02 11 133 "SMIM17,BACH1,LDHD,LETMD1,ZNF44,IBA57,PDE1B,NSD1,SSBP2,ZNF610,CFAP298" MicroRNA hsa-miR-664a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.29E-03 1.00E+00 1.01E-02 9.34E-02 11 133 "SMIM17,BACH1,LDHD,LETMD1,ZNF44,IBA57,PDE1B,NSD1,SSBP2,ZNF610,CFAP298" MicroRNA hsa-miR-1193:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.32E-03 1.00E+00 1.02E-02 9.36E-02 9 98 "ABCF1,XKR4,CRY2,MRPL10,MAP2,ZSCAN2,CHD9,POGZ,MSRB3" MicroRNA hsa-miR-181a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.79E-03 1.00E+00 1.07E-02 9.83E-02 8 82 "TAOK1,ATP1A3,ABCG2,MIER3,THYN1,PSD,ATXN2,ZNF138" MicroRNA hsa-miR-4323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.79E-03 1.00E+00 1.07E-02 9.83E-02 8 82 "TEX22,TMEM184B,CS,ABCC5,STMN1,NEXMIF,PKNOX2,RPL7L1" MicroRNA hsa-miR-4275:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-03 1.00E+00 1.07E-02 9.89E-02 7 66 "LIN54,EIF4G2,ZNF391,FOXO3,STRN3,SPDL1,ARL10" MicroRNA hsa-miR-4652-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-03 1.00E+00 1.07E-02 9.89E-02 7 66 "TBPL1,SEPT9,SESN1,TDRKH,PKM,POLR2F,USP22" MicroRNA hsa-miR-8059:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-03 1.00E+00 1.07E-02 9.89E-02 7 66 "VPS26C,GTF2IRD2,KCTD15,PRKAB2,COPZ1,NFASC,TUBB2A" MicroRNA hsa-miR-4471:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-03 1.00E+00 1.07E-02 9.89E-02 7 66 "VPS26C,GTF2IRD2,KCTD15,PRKAB2,COPZ1,NFASC,TUBB2A" MicroRNA hsa-miR-4712-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-03 1.00E+00 1.07E-02 9.89E-02 7 66 "CS,GOLGA7,ADAM22,ZNF426,ZNF667,ZNF23,ZNF138" MicroRNA hsa-miR-6759-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.10E-02 1.01E-01 6 51 "SEC23B,CLDN11,PFKFB3,MINDY2,KLHL4,EML6" MicroRNA hsa-miR-4720-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.10E-02 1.01E-01 6 51 "CACNA2D1,GOLGA7,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-5588-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.10E-02 1.01E-01 6 51 "CACNA2D1,GOLGA7,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-3135a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.10E-02 1.01E-01 6 51 "KIAA1324,DNAL1,AGBL5,SETD5,SLC2A5,SLC8A1" MicroRNA hsa-miR-4734:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-02 1.00E+00 1.12E-02 1.03E-01 4 24 "CACNA1A,SCIN,NFIX,RXRA" MicroRNA hsa-miR-4718:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-02 1.00E+00 1.12E-02 1.03E-01 4 24 "PRKCB,PSD,SBF1,URM1" MicroRNA "AGTCTAG,MIR-151:MSigDB" "AGTCTAG,MIR-151:MSigDB" MSigDB 1.03E-02 1.00E+00 1.12E-02 1.03E-01 4 24 "RTL9,CACNB4,HPCAL4,CAMTA1" MicroRNA hsa-miR-520g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-02 1.00E+00 1.13E-02 1.04E-01 5 37 "CALM1,EIF4G2,MSANTD4,TJAP1,VSNL1" MicroRNA hsa-miR-4764-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-02 1.00E+00 1.13E-02 1.04E-01 5 37 "DDO,LRIG1,MED12L,ZNF274,BDP1" MicroRNA hsa-miR-668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-02 1.00E+00 1.13E-02 1.04E-01 5 37 "PHF12,MALT1,BTBD3,KLHL4,DHX33" MicroRNA hsa-miR-6070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-02 1.00E+00 1.13E-02 1.04E-01 3 13 "SORCS2,EXOSC10,ALG9" MicroRNA hsa-miR-3683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-02 1.00E+00 1.13E-02 1.04E-01 3 13 "XKR4,NR1D2,NELFE" MicroRNA hsa-miR-6889-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-02 1.00E+00 1.14E-02 1.05E-01 8 83 "CLK4,CELF1,HSPA4L,USP22,DICER1,ZNF70,SLC30A4,GDPD5" MicroRNA hsa-miR-1180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-02 1.00E+00 1.16E-02 1.07E-01 7 67 "EIF1,RACK1,METTL21A,KANSL1,FAM200B,HPS4,VPS35L" MicroRNA hsa-miR-300:Functional MTI Functional MTI miRTarbase 1.09E-02 1.00E+00 1.18E-02 1.09E-01 10 118 "SPAG9,COPB2,SEMA4D,ZNF181,ZNF546,MBNL1,MID1,PRKCB,CNKSR2,SLC6A8" MicroRNA hsa-miR-1273d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-02 1.00E+00 1.20E-02 1.11E-01 6 52 "ATP1B3,ELMSAN1,EIF1,FAM69A,SLC6A17,SNX22" MicroRNA hsa-miR-148b-5p:Functional MTI Functional MTI miRTarbase 1.11E-02 1.00E+00 1.20E-02 1.11E-01 6 52 "BOC,APC2,NPTX2,PEG10,NSD1,NACC2" MicroRNA hsa-miR-4305:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-02 1.00E+00 1.26E-02 1.16E-01 5 38 "TAOK1,FRMD5,KIT,SPART,ATP6V0E2" MicroRNA hsa-miR-4288:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-02 1.00E+00 1.26E-02 1.16E-01 5 38 "CACNA1A,FOXF2,THYN1,PDPK1,FAIM2" MicroRNA hsa-miR-624-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-02 1.00E+00 1.26E-02 1.16E-01 5 38 "ADAM22,PTPRG,FIGN,UBR7,RMI1" MicroRNA hsa-miR-598-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-02 1.00E+00 1.29E-02 1.18E-01 4 25 "CASP8AP2,TUBD1,SPIN1,BTBD3" MicroRNA hsa-miR-4798-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-02 1.00E+00 1.29E-02 1.18E-01 4 25 "MPP6,ELOVL5,USP51,TMOD2" MicroRNA hsa-miR-1273c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-02 1.00E+00 1.29E-02 1.18E-01 4 25 "XKR4,NR1D2,ARL10,NELFE" MicroRNA hsa-miR-191-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-02 1.00E+00 1.29E-02 1.18E-01 4 25 "DPY19L3,MTX3,SSTR2,RPL7L1" MicroRNA hsa-miR-1199-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-02 1.00E+00 1.30E-02 1.20E-01 8 85 "RGS11,CELF1,TDRKH,MUM1,NKD1,NFIX,NPTX2,ZXDA" MicroRNA hsa-miR-4463:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-02 1.00E+00 1.30E-02 1.20E-01 8 85 "CC2D2A,DOCK11,KIAA0586,EGR3,GPR173,SEPT8,WNK3,FXR1" MicroRNA hsa-miR-8083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "SPOP,ABCD2,TRMT9B,CREM,GPR137C,NR2C2" MicroRNA hsa-miR-5681b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "TMEM184B,MIER3,ZNF426,ZNF793,CNKSR2,MPPE1" MicroRNA hsa-miR-3912-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "ARHGDIA,CELF1,FUT10,SHC3,CSRNP3,NR2E1" MicroRNA hsa-miR-6510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "ZNF555,GAPVD1,IP6K1,SGSM2,ZNF331,ADAMTS17" MicroRNA hsa-miR-3940-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "CFAP410,NRXN3,ZNF585B,GPR75,C12orf49,RXRA" MicroRNA hsa-miR-1180-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "RGS11,MRPL10,XRRA1,STX1B,SZT2,CBX5" MicroRNA hsa-miR-7114-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-02 1.00E+00 1.31E-02 1.21E-01 6 53 "RGS11,MRPL10,XRRA1,STX1B,SZT2,CBX5" MicroRNA hsa-miR-523-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-02 1.00E+00 1.32E-02 1.22E-01 2 5 "LTBP4,KIAA0930" MicroRNA hsa-miR-4788:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-02 1.00E+00 1.32E-02 1.22E-01 2 5 "NFIX,SIGLEC10" MicroRNA hsa-miR-6789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-02 1.00E+00 1.35E-02 1.24E-01 7 69 "DOCK11,ZMYM4,LETMD1,CHST6,NFIX,LAT2,GAN" MicroRNA hsa-miR-4744:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-02 1.00E+00 1.35E-02 1.24E-01 7 69 "FRY,SARAF,GCK,AFF1,GPR137C,ZNF827,ZC3H13" MicroRNA hsa-miR-219a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-02 1.00E+00 1.35E-02 1.24E-01 7 69 "ZNF385A,USP6NL,CELSR3,FICD,IL6R,NKAIN1,MTMR14" MicroRNA hsa-miR-4764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-02 1.00E+00 1.35E-02 1.24E-01 7 69 "DLGAP2,LRWD1,SEC24C,FGFR3,FAM49B,AGBL5,GPR137C" MicroRNA hsa-miR-371-3p:PITA hsa-miR-371-3p:PITA_TOP PITA 1.28E-02 1.00E+00 1.39E-02 1.28E-01 3 14 "USP37,ZNF385A,ARX" MicroRNA hsa-miR-154-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-02 1.00E+00 1.39E-02 1.28E-01 5 39 "MMP16,KANSL1,FIGN,MCMBP,SYPL1" MicroRNA hsa-miR-6718-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-02 1.00E+00 1.39E-02 1.28E-01 5 39 "DST,ZC3H11A,RAB30,SH3TC2,CNKSR2" MicroRNA hsa-miR-203b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-02 1.00E+00 1.39E-02 1.28E-01 5 39 "DST,ZC3H11A,RAB30,SH3TC2,CNKSR2" MicroRNA hsa-miR-625-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-02 1.00E+00 1.39E-02 1.28E-01 5 39 "BAG4,FKTN,FIGN,PEG10,USP1" MicroRNA hsa-miR-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "SEC14L5,LONRF1,C2CD2L,EGFR,SEPT4,ZNF138" MicroRNA hsa-miR-4774-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "CYBB,GOLGA7,SOWAHA,PEX26,FAM124A,VLDLR" MicroRNA hsa-miR-6806-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "ST3GAL5,UBXN2A,SESN1,NCAM2,SMOX,POLR2F" MicroRNA hsa-miR-3173-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "ARHGEF2,CPS1,FAM107A,TRIM67,CPEB4,GDPD5" MicroRNA hsa-miR-200a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "CPS1,CS,OLA1,ZMAT4,CLIP1,ZNF138" MicroRNA hsa-miR-6799-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-02 1.00E+00 1.43E-02 1.31E-01 6 54 "ARHGEF2,CPS1,FAM107A,TRIM67,CPEB4,GDPD5" MicroRNA hsa-miR-4714-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-02 1.00E+00 1.45E-02 1.33E-01 7 70 "IGDCC3,TUBD1,ZNF678,KLHL23,BCAS3,NCBP3,DIP2A" MicroRNA hsa-miR-503:PITA hsa-miR-503:PITA_TOP PITA 1.34E-02 1.00E+00 1.45E-02 1.33E-01 7 70 "PPFIA3,EIF4G1,IGF1,MAPK3,ZNF423,CSMD1,CELF4" MicroRNA hsa-miR-1539:mirSVR_highEffct hsa-miR-1539:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-02 1.00E+00 1.45E-02 1.33E-01 7 70 "MARK4,DLX1,FCGR3A,CHL1,STMN2,PACSIN2,NPDC1" MicroRNA hsa-miR-4504:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-02 1.00E+00 1.45E-02 1.33E-01 7 70 "CACNA1B,TBPL1,SOCS5,KIAA0408,KIT,TPCN2,ZNF708" MicroRNA hsa-miR-181d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-02 1.00E+00 1.47E-02 1.35E-01 4 26 "HCN2,ING4,TNK2,C2orf72" MicroRNA hsa-miR-4785:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-02 1.00E+00 1.47E-02 1.35E-01 4 26 "MYADM,SPATA2,LIFR,DBNDD2" MicroRNA hsa-miR-6751-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-02 1.00E+00 1.48E-02 1.36E-01 8 87 "RGS11,CELF1,TDRKH,MUM1,NKD1,NFIX,NPTX2,ZXDA" MicroRNA hsa-miR-7978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-02 1.00E+00 1.54E-02 1.42E-01 5 40 "IGLON5,DNAJB6,ZC3H4,ARL10,KCNK12" MicroRNA hsa-miR-6808-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-02 1.00E+00 1.54E-02 1.42E-01 5 40 "CHRDL1,TJAP1,SH3TC2,CNKSR2,SZT2" MicroRNA hsa-miR-5195-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-02 1.00E+00 1.54E-02 1.42E-01 5 40 "SRSF11,DBN1,MIER3,MYO5A,ASTN2" MicroRNA hsa-miR-4515:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-02 1.00E+00 1.54E-02 1.42E-01 5 40 "ESYT2,LDB2,E2F6,RNF165,KCTD15" MicroRNA hsa-miR-4466:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-02 1.00E+00 1.55E-02 1.43E-01 6 55 "ESYT2,DIS3L,AKAP5,FITM2,INAVA,NMNAT2" MicroRNA hsa-miR-3150a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-02 1.00E+00 1.67E-02 1.54E-01 4 27 "STX16,SLC35G1,LSAMP,RFX2" MicroRNA hsa-miR-3150b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-02 1.00E+00 1.67E-02 1.54E-01 4 27 "STX16,SLC35G1,LSAMP,RFX2" MicroRNA hsa-miR-4796-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-02 1.00E+00 1.67E-02 1.54E-01 4 27 "PTCHD1,NFS1,CD99L2,INPP5B" MicroRNA "GTAGGCA,MIR-189:MSigDB" "GTAGGCA,MIR-189:MSigDB" MSigDB 1.55E-02 1.00E+00 1.67E-02 1.54E-01 4 27 "ARHGEF2,GPHN,BTBD3,KCNAB1" MicroRNA hsa-miR-184:PITA hsa-miR-184:PITA_TOP PITA 1.55E-02 1.00E+00 1.67E-02 1.54E-01 4 27 "EPB41L5,ADGRB2,MTCL1,ZFPM2" MicroRNA hsa-miR-5190:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.68E-02 1.54E-01 8 89 "ABCD2,RCAN1,MRNIP,ERC1,SPART,MPRIP,KIAA0930,ZNF154" MicroRNA hsa-miR-3663-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.68E-02 1.55E-01 6 56 "APBB2,DDR1,DOT1L,KCTD15,SLC6A8,TUBB2A" MicroRNA hsa-miR-4475:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.68E-02 1.55E-01 6 56 "NCKAP5,TAOK1,ARHGEF2,FBXW11,TUBB2A,UBTF" MicroRNA hsa-miR-584-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.68E-02 1.55E-01 6 56 "ZNF582,THSD7A,GSN,NOVA2,SETD5,SLC37A2" MicroRNA hsa-miR-671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.68E-02 1.55E-01 3 15 "SORCS2,DIS3L,FAM208A" MicroRNA hsa-miR-516a-5p:PITA hsa-miR-516a-5p:PITA_TOP PITA 1.56E-02 1.00E+00 1.68E-02 1.55E-01 3 15 "FIGN,STX1B,PLCB1" MicroRNA hsa-miR-490-5p:Functional MTI Functional MTI miRTarbase 1.58E-02 1.00E+00 1.70E-02 1.56E-01 5 41 "TAOK1,GPR137C,CNNM2,FAM102A,ZNF28" MicroRNA hsa-miR-1251-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-02 1.00E+00 1.70E-02 1.56E-01 5 41 "MARCH4,CABP7,DCTN4,ATP13A4,SNRK" MicroRNA hsa-miR-632:Functional MTI Functional MTI miRTarbase 1.58E-02 1.00E+00 1.70E-02 1.56E-01 5 41 "CACNA1A,FOXF2,THYN1,PDPK1,FAIM2" MicroRNA hsa-miR-6826-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-02 1.00E+00 1.70E-02 1.56E-01 5 41 "CLOCK,KPNA5,ZNF680,PRDM10,HNRNPA3" MicroRNA hsa-miR-626:Non-Functional MTI Non-Functional MTI miRTarbase 1.58E-02 1.00E+00 1.70E-02 1.56E-01 5 41 "C1orf52,TENM1,KIAA1755,FAM214B,ZMAT3" MicroRNA hsa-miR-3620-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-02 1.00E+00 1.82E-02 1.67E-01 6 57 "IPCEF1,ZMAT1,NPTX1,PKM,SLC6A8,TUBB2A" MicroRNA hsa-miR-2117:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-02 1.00E+00 1.82E-02 1.67E-01 6 57 "TUBGCP4,TNRC6A,PDE1B,PDPK1,ZNF793,DNAJC9" MicroRNA hsa-miR-1587:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-02 1.00E+00 1.82E-02 1.67E-01 6 57 "IPCEF1,ZMAT1,NPTX1,PKM,SLC6A8,TUBB2A" MicroRNA hsa-miR-4497:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-02 1.00E+00 1.87E-02 1.72E-01 5 42 "CBARP,SH2B1,ATP13A4,CAMK2N2,UGT8" MicroRNA hsa-miR-4634:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-02 1.00E+00 1.87E-02 1.72E-01 5 42 "RNF157,CDC14B,TUBD1,SNX22,GPR161" MicroRNA hsa-miR-521:PITA hsa-miR-521:PITA_TOP PITA 1.76E-02 1.00E+00 1.89E-02 1.74E-01 4 28 "OSBPL3,MAST1,SOX11,CLASP2" MicroRNA hsa-miR-4677-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-02 1.00E+00 1.91E-02 1.75E-01 7 74 "CHRDL1,RASGRP1,APC2,FNBP1,SEPT8,KLHL7,CBX5" MicroRNA hsa-miR-4741:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-02 1.00E+00 1.91E-02 1.75E-01 7 74 "ABCC5,CELF1,PKM,PRRT2,SBF1,PEX26,THRA" MicroRNA hsa-miR-1295:PITA hsa-miR-1295:PITA_TOP PITA 1.79E-02 1.00E+00 1.92E-02 1.76E-01 2 6 "EGR3,TCEAL5" MicroRNA "CGGTGTG,MIR-220:MSigDB" "CGGTGTG,MIR-220:MSigDB" MSigDB 1.79E-02 1.00E+00 1.92E-02 1.76E-01 2 6 "SPTBN4,LHX2" MicroRNA hsa-miR-758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-02 1.00E+00 1.96E-02 1.81E-01 6 58 "CHRDL1,TLR7,ZNF181,TJAP1,CNKSR2,TACC1" Drug ctd:D003042 Cocaine CTD 5.35E-27 2.34E-22 2.34E-22 2.64E-21 281 1317 "SYN3,CLK4,AS3MT,NDRG2,GALNT16,ADCY8,ADORA1,ADORA2A,ADRA1B,SLC24A4,MTUS1,HECW2,AGT,OSBPL1A,TBC1D14,C1QTNF1,SPARCL1,SEMA6A,ALCAM,SYT13,BEGAIN,AMH,SEMA7A,PPFIA3,CDC14B,SEMA4G,ARNTL,RGS20,DYNLL1,ATP1A1,ATP1A3,SLC4A4,ATP1B3,MYOM1,RIPK1,AZGP1,BACH1,BCHE,RGS9,HCN2,NRP2,BID,CFLAR,LDHD,ARHGEF7,FUBP1,BTK,CA4,CALM1,KALRN,CAMK2A,CAMK2B,RUNX1T1,CBLN1,LDB2,KRIT1,ARHGEF1,SCARB1,ENTPD2,LRRFIP1,LARGE1,CHN1,CHRNA4,CLTB,TMEM184B,HOMER3,CNR1,WHRN,MAGED1,CLOCK,PREPL,CREM,CRY2,RNF14,SNCAIP,CSF2RA,SIPA1L1,PDE4DIP,APPL1,GPSM1,CYBB,GPRASP1,SNPH,DCAF8,AIF1L,JAKMIP2,ELMO1,TIAM2,SNAP91,GRIN3A,DNM1,HS3ST2,DYNC1I1,DPYSL2,DRP2,FAM78B,ABCC5,EDN1,EDNRA,EDNRB,KLHL5,APH1A,EGFR,EGR3,ENO2,EPHB1,NCALD,EYA1,NRN1,PTK2B,ST3GAL6,FDFT1,PPP1R1B,OLFM1,FGF12,FGFR1,ATP5PD,HPCAL4,AGAP2,SEMA4D,FLYWCH1,SYT3,CSPG5,MEGF10,GABBR1,GABRB3,GABRG2,GAD1,RAPGEF6,CPLX1,TUBA8,NFU1,GFRA2,GNAO1,GPER1,GRIA2,SPACA9,GRIK5,GRIN2C,GRIN2D,ATE1,GRM2,GSN,GUCY1A1,GUCY1B1,FRMD5,BACH2,IDH3A,ITPKB,KCNB1,KCND1,KCND2,LAMP2,LSAMP,MAP2,MAP6,MARK1,MAT2A,MBD1,MBP,PTOV1,TAGLN3,MYO5A,NCF2,NEFM,NEFH,NF1,NFIX,NPY,NPTX2,NTRK2,CLDN11,OXTR,PCDHGC3,PCDH8,CDK18,PDPK1,OLA1,ZDHHC8,SERPINI1,SEMA5B,PKM,PLEC,SLC25A23,NECAB2,RETREG2,SEPT4,POLR2F,PPP2R2B,PPP2R2C,PPP3CA,PPP5C,PRKCB,MAPK3,MAPK10,PTK2,PTN,PTPRB,CASTOR1,PEX2,RASGRF1,CRTAC1,DPF2,RGS4,RORB,BAALC,CLIP1,STX1B,RYR3,AP1AR,S100B,SATB1,SCN2B,MRAS,SGK1,AMBRA1,R3HDM2,CNKSR2,SYBU,SLC4A3,DHX30,LIMS2,PKNOX2,CCDC88A,SLC14A1,SNCA,FAIM2,KDM3A,ZHX3,SPTAN1,RBM26,TROVE2,SSTR1,SSTR2,ERBIN,SEPT8,STXBP1,SUPT5H,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,TACC1,TACR1,DNMBP,ADGRL3,TCF4,SATB2,SYNE1,OBSL1,ARHGAP9,CRTC1,PCDHA2,DICER1,ZFPM2,SLC44A1,THRA,ENHO,NACC2,RELL2,TMPO,PRRT1,SYNPO2,SGK3,FAM155A,UBE3A,UBTF,UCHL1,PLPPR2,ANKS1B,TFIP11,MFF,SEMA3B,SLC17A7,KCNAB1,WNK3,AMN1,NETO2" Drug ctd:C046012 pentanal CTD 9.95E-26 4.36E-21 2.18E-21 2.46E-20 310 1531 "VWA5B2,GALNT16,TMCC3,ADRB2,SLC24A4,OSBPL6,TXNDC16,C1QTNF3,SRPX,CEP126,MARCH4,PDZD4,BEGAIN,ZFAT,MAGEE2,BCAS1,CDK10,SFMBT2,PPP4R4,IGDCC4,ARHGDIG,ARRB1,PLA2G4C,TMEM108,ATP1A3,RNF182,ALDH7A1,KIF1A,ADGRB1,RGS9,CFLAR,BMP7,ARHGEF7,CACNA1G,GPC2,BAIAP3,IL33,LDLRAD4,CFAP410,CA4,LURAP1,CALB2,CCK,KRIT1,DCLK1,CRLF1,PLEKHB1,ARHGAP22,LHX2,RAB33A,NGEF,RAB26,FAM149A,ZNF521,IGDCC3,CLOCK,CRMP1,CRYM,CSF1R,CSF2RA,GALNT9,RIMS4,PDE4DIP,ARHGEF4,ARHGAP24,DCAF8,RASSF2,MAML1,DAPK1,AIF1L,KIAA0319,KLHL3,TMEM130,LYPD1,GUCD1,KIF19,ZNF582-AS1,MED12,NR1D2,CPEB2,DUSP9,RASGRP1,TMTC1,FAM13A,EBI3,MRO,KMT5B,PLXNC1,C8orf37,PAN3,RASGRP2,RRAGB,F5,REEP2,PSMA3-AS1,FKTN,GORAB,GTF2IRD2,HPCAL4,AGAP2,SYT3,EFCAB2,KHDRBS3,ST6GALNAC3,NSG1,FYN,MEGF11,GAD1,GATM,GPR162,MALT1,HPGDS,AIFM3,KCNMB4,DCLK2,GNAO1,STON1,GPR37,TMEM121B,CNTRL,DIDO1,C1QL4,CIT,BTN2A1,LINGO1,ADAMTS6,GUCY1B1,SLC2A6,TOX2,PADI2,NXPH3,FRMD5,HNMT,ICA1,IRF8,MSL1,SHISAL1,LRRC25,NKD1,NIM1K,IL6R,ITGA7,C2CD4C,KCNF1,KCNH2,KCNN1,CREG2,LINC00634,L1CAM,CAMK2N2,LMO2,MAPT,MBP,CHST6,ADAM11,MGAT3,SCAMP5,XRRA1,MOV10,MX1,LAYN,NEXMIF,MYT1,FXYD7,NEFM,CCDC13,CNOT4,NOVA2,NPTX1,ZNF713,P2RY1,ZNF827,GLIPR1L2,DPY19L2P2,PCDH9,PDE3A,PDE4D,PDPK1,GNG2,OLA1,ZDHHC8,DUSP26,TMEM38A,KCTD15,JAKMIP1,PLIN1,NECAB2,ING3,SEPT4,FA2H,FSD1,PPARA,PPP2R2B,VSTM2L,RASGEF1B,PRKACB,MAPK10,GRAMD1C,SMIM10L2B,PRPH,GDPD1,LAMA1,CNTLN,PTX3,PEX2,TMEM231,PID1,TMEM255A,FAM66C,FAT4,FAM184A,RASGRF2,RADX,RET,ERI2,FIGN,RNASE1,ZNF532,TMLHE,KLHDC8A,CARF,NEK11,EPHA10,RPS6KA2,MAP6D1,LRRK2,MEG3,ATAT1,KCNIP3,SCP2,TNFRSF19,FERMT1,CPEB3,MYO18A,ABLIM3,FAM81A,LIMS2,SLC6A8,SLC8A1,SLC14A1,BTBD7,TET1,MAST1,OGDHL,SNCA,KIF13A,NMNAT2,KDM4C,UNC5B,ZC3H13,DBNDD2,NFASC,SSTR2,ELOVL4,STAC2,SULF2,SEPT3,ARHGEF9,ARC,SYN2,SLC37A2,CAMTA1,NR2F1-AS1,WSCD1,CLASP1,NAT16,DOCK9,FAM189A1,OBSL1,GPRIN3,PCDHA3,PCDHA1,ENHO,TIAM1,ERCC6L2,BEX4,RASD2,TPM1,NPL,TRO,HIRA,RPRM,LINC00689,VAV1,VGF,LMF1,LAT2,TCEAL7,CELF4,ZNF154,REEP1,DPYSL5,ANKS1B,SLC30A3,EMSY,PRDM8,NAV3,WNK2,EPM2A,HRASLS,ZNF37BP,TMEM63C,PHTF2,NLRP3,TIGD6,ADAMTS10,RNF146,PRRT4,SENP7,JPH3" Drug ctd:C496932 panobinostat CTD 3.99E-20 1.75E-15 5.83E-16 6.57E-15 263 1335 "ASIC1,AS3MT,EMILIN3,XKR4,AXIN2,UNC5A,RNF150,PTCHD1,SORCS2,CC2D2A,ALCAM,PCDH10,BEGAIN,EPB41L5,GAS7,SFMBT2,ARRB1,RNF182,NRP2,CFLAR,LDHD,BMP7,BMPR1B,DST,JAZF1,CA4,CA8,CA12,CACNA2D1,CALB2,SPAG9,RUNX1T1,SLC16A4,CDH2,DCLK1,LRRFIP1,CLGN,NOG,SLIT2,LHX2,RAB33A,NGEF,ABCG2,CNTN1,FAM149A,COL9A3,ZNF521,IGDCC3,CNRIP1,C2CD2,AKAP12,HAPLN1,TRIM69,CSF2RA,LRIG1,LRRC3B,PDE4DIP,KIAA0040,DCAF4,BOC,ARHGAP24,PABPC5,BRINP1,ZNF804A,MFAP3L,DYNC1I1,CDON,RCAN1,EBF1,EDN1,EDNRA,EDNRB,EBI3,PLXNC1,PCOLCE2,LRRC17,RASGRP2,DENND4A,NCALD,CEP85L,ETV1,PIPOX,ADGRV1,DLC1,CHST15,SLC9B2,SPSB4,FGFR3,SYNCRIP,ATP13A4,FLT1,CSPG5,FUT9,TVP23A,HRASLS5,GABRB3,DENND2A,GAD1,ERAP1,ADAM28,FREM1,TOX3,MAP7D2,KCNMB4,DCLK2,LNX1,PRUNE2,TDRKH,STON1,GPR37,STMN2,KAT7,GUCY1A1,HAS2,TOX2,HNMT,NEGR1,SHISA6,CELF5,MSL1,IDH3A,IFI16,NKD1,KIAA1755,LRRTM1,METTL21A,KCND2,KCNN3,KIT,L1CAM,LAMA2,TMEM110-MUSTN1,LAMP2,LIFR,LMO2,SYTL4,NCOA7,MAP2,MAP6,SHC3,MEF2C,MEIS2,MGAT3,KITLG,ADAM22,MYCN,LAYN,NEXMIF,BEX5,NDP,NEFM,NELL2,NF1,NFE2L2,ALDH1L2,CNOT4,NPY,ZNF827,PAX6,DPY19L2P2,PCDH8,PDE3A,PDE4D,ENPP2,GPR173,TMOD2,OLA1,PKM,PURG,LRP12,SH3KBP1,IRX1,PPP1R1A,ZFHX4-AS1,PPP2R2B,LRRN3,PRKCB,MAPK3,MAPK10,PRODH,RELN,SNRK,ELOVL2,STK32A,PTPRN2,PTPRO,PID1,ENOX1,FIGN,RFX3,ROBO2,ARMH4,RTN1,RYR3,S100B,SEMA6D,CSRNP3,SCN2B,SCN7A,ZFP2,HSPA4L,ARX,FERMT1,FHOD3,CNKSR2,NLGN1,PKNOX2,SLC6A8,GKAP1,COA1,LIMCH1,SNAP25,KIF13A,SOX3,SOX11,DOK5,NMNAT2,SPP1,CDK19,NFASC,LMO3,CLSTN2,SST,SOX21-AS1,SULF2,ADAMTS17,COBL,ASTN2,TACC1,ADGRL3,ZEB1,SYNE1,DOCK9,SLC19A3,SLC35G2,RNF175,FAM200B,FAM124A,TRPS1,SSBP2,TUBB2A,SGK3,RPRM,FAM155A,UGT8,FLRT2,CCDC136,LMF1,RBFOX3,PCDH20,ZIC1,TRIM9,ANKS1B,SLC30A4,TUBA1A,TMEM178A,NAV3,FAM13C,FZD3,KAT6A,PHTF2,ST8SIA2,CPNE4" Drug ctd:C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester CTD 5.87E-18 2.57E-13 6.43E-14 7.25E-13 176 810 "AS3MT,CCDC85A,AXIN2,ADORA1,ADRB2,ZNF608,PCDH19,OSBPL1A,NME5,OSBPL6,SORCS2,C1QTNF1,C1QTNF3,SEMA6A,ARHGAP20,LCORL,APBB2,SFMBT2,PRX,ARNTL,RASL11B,ATP1B3,ATP6V0A1,DOCK11,ADAM23,NRP2,GPR146,BMPR1B,ST3GAL5,CACNA1G,IL33,CAMK2G,CH25H,CBR1,USP2,MTMR7,P2RX6,CD86,CD38,DCLK1,CBARP,FAM189A2,PCYT1B,ZFP28,NECTIN3,ANKRD44,NCOR1,SNCAIP,CSF1,VCAN,SOCS5,PLXNA4,CTH,HDAC9,GPRASP1,RASSF2,DAPK1,SPOCK2,PITPNC1,ELMO1,MFAP3L,RUSC2,LYPD1,GSDME,TMCC2,DLX1,DYNC1I1,CDON,CPEB2,SLC12A6,DUSP9,EDN1,SEMA3D,KMT5B,EGR3,RGS17,HSPA12B,TBC1D16,ST3GAL6,FER,OLFM1,FGFR1,MEX3B,FLT1,PDLIM5,STAU2,MEGF10,GALNT15,RAPGEF6,MTHFD2,CSDC2,GGT5,GHR,MALT1,GLUL,AIFM3,TDRKH,SLC2A6,MAP4K5,NXPH3,HLF,IGF1,NKD1,GAREM2,DISP2,IL6R,KTN1,HECTD2,GPR155,MBP,SRSF12,PPM1L,AFDN,MMP17,MPP2,MYCN,MYO7A,RTL5,NBL1,NFE2L2,SERPINI1,KCTD15,PLCL1,PCDH18,PPP2R2B,PPP3CC,PKIA,DIRAS2,MASP1,PTPRB,PTX3,PEX2,FAT4,FIGN,KLHDC8A,CLIP1,TNFRSF19,SMPD3,GALNT10,HSPA4L,ST8SIA1,SLC12A2,SLC14A1,SLC22A4,SNCA,MBD5,PDZD2,SOX11,NMNAT2,HECW1,ITPRID2,SYNE2,RHBDL3,VPS13A,PLCB1,COBL,TPCN2,FRYL,ZFPM2,TIAM1,CBX5,NPL,TRPS1,SSBP2,PLEKHH2,VGF,VLDLR,CLDND1,TMEM237,DPYSL5,ADAMTS9,PCBP4,FBXO36,TTC7A,NETO2,SPATA13" Drug 994_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.96E-17 8.57E-13 1.71E-13 1.93E-12 66 191 "ASPHD1,NDRG2,PPP4R4,ARRB1,CDK13,PDE8B,MARK4,MTMR3,RAB29,CAMK2B,KYAT1,SCARB1,CLGN,FOXN3,AKAP12,ARHGEF10,PDE4DIP,RASSF2,DBN1,ARMCX2,SLC12A6,DTNA,OPTN,ENO2,VPS26C,ZNF589,FGF12,CSPG5,FYB1,GALC,DISC1,GRB10,SPACA9,MAP4K5,KCNH2,LIG4,LMO2,LYRM9,CNOT4,NPR2,PALM,PDE4A,SLC25A23,PLTP,GRAMD1C,SAMD9,PTCH1,CEP97,FAM184A,CARF,RASA3,PEX26,SLC6A8,BTBD7,SLC22A4,LIMCH1,SPTAN1,TROVE2,TTBK2,PLCB1,ZNF34,TPM1,VGF,MAP3K12,GDPD5,RNF170" Drug ctd:C042720 mercuric bromide CTD 2.06E-15 9.02E-11 1.50E-11 1.69E-10 209 1077 "ASPHD1,ASIC1,BEND6,OSBPL6,SEMA6A,ALCAM,PCDH10,PPFIA4,APBA2,EPB41L5,CDC14B,ARRB1,ZBTB10,CCAR2,KIF1A,BCHE,BMP7,SYNJ2,JAZF1,CA4,CALB1,THSD7A,CARS,RUNX1T1,ARHGEF25,SYNGR3,DGKI,TIGD7,NOG,SLIT2,LHX2,RAB33A,NRXN3,ABCG2,MAP4K4,FAM149A,ZNF521,NSL1,HAPLN1,SNCAIP,CSF2RA,LRRC3B,OSBPL3,FAM169A,CTH,BOC,RIPOR2,IST1,ZBTB24,MFAP3L,SNAP91,CHRDL1,CPEB2,DTNA,EBF1,EDN1,EDNRB,KLHL5,PLXNC1,TMEM132E,LINC-PINT,EPHB1,NCALD,CEP85L,F5,FAM198B,DLC1,FECH,SPSB4,FLNC,FLT1,CSPG5,MEGF10,GABRB3,ERAP1,SESN1,ADAM28,FREM1,PCDH17,LYVE1,COPS8,DCLK2,LNX1,PRUNE2,GPR37,ATP2B1-AS1,PRDM5,FAM19A2,FAM222A,UBE2QL1,FRMD3,HNMT,SHISA6,CELF5,IDH3A,IFI16,SHISAL1,ZIC5,KNDC1,SCIN,IL6R,LAMP2,LIFR,SFXN5,NCOA7,LSAMP,CLEC18A,MAP4,MAP6,SHC3,KITLG,MITF,MMP16,LAYN,NEXMIF,NDP,NEFM,NEFH,NF1,NFE2L2,ALDH1L2,CNOT4,NPY,NPTX1,CLDN11,PAX6,PCDH8,PCDH9,PCSK1,PDE3A,PDE4B,PDE4D,SLC10A4,TMOD2,SERPINI1,RETREG1,PCDH18,PPP1R1A,PPP2R2B,PRKCB,EPDR1,MAPK10,GRAMD1C,RELN,VPS13C,STK32A,PTX3,PEX2,TMEM231,ZNF493,RASGRF2,RET,REV3L,RFX2,PRIMA1,KLHDC8A,TNFRSF19,GALNT10,HSPA4L,SGK1,ARX,FHOD3,CNKSR2,SYBU,PKNOX2,SLC6A8,COA1,LIMCH1,SNCA,SPP1,CDK19,NFASC,LMO3,SST,SOX21-AS1,SULF2,ARHGEF9,TMEM150C,TACC1,IQCE,KLHL4,NR2F1-AS1,SATB2,TRIM2,SYNE1,DOCK9,SLC35G2,HIF3A,DICER1-AS1,ZMAT3,FAM124A,PIK3R5,RGMB,RUNDC3B,NEIL2,TRPS1,TSC2,SGK3,RPRM,UCHL1,CCDC136,RBFOX3,PCDH20,CADM2,TUBA1A,FAM13C,DOCK8,KAT6A,MSRB3" Drug ctd:C029790 "2,2',3',4,4',5-hexachlorobiphenyl" CTD 6.58E-15 2.89E-10 4.12E-11 4.64E-10 322 1885 "VWA5B2,ABR,ACHE,USP31,TEX22,WDR35,ADGRF5,SEMA6A,SPOP,ARHGAP20,AMH,AMPH,BIN1,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,ASGR1,ASPA,CCDC74A,PTCH2,ZBTB10,NUMB,ATP1A1,ATP1A3,ATP2A2,ATP2B2,ATP6V1G2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,RUNX1T1,PRC1,CCK,CD38,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN1,CHN2,PLEKHB1,LHX2,NRXN3,PLAA,CLTC,HOMER3,COX4I1,ZNF521,NSL1,CREM,ENTPD4,ARHGEF10,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,ARHGEF4,SEC14L5,MATR3,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,ALKBH8,SACS,SPOCK3,SGSM2,DMD,DNM1,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,PLXNC1,TMEM132E,EIF5,PLEKHA1,ENO2,APC2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,F5,RPS6KC1,TUBA1B,PTK2B,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,FGFR3,ATP5PD,MEX3B,HPCAL4,AGAP2,ZMYND15,FLT1,NBEA,SMC2,CAMKK2,CELF1,STAU2,GAA,GALNT15,ZNF274,DISC1,SRRM4,CPLX1,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,GLUL,MAP7D2,GNAL,PRUNE2,TDRKH,GPR37,CNTRL,GRIN2C,ATE1,ZNF496,GSN,RNF165,GSTT2,ZBTB49,BVES,FAM107A,HAS2,NXPH3,HNF4G,IGFBPL1,CPT1C,DHX35,MYLK2,SOWAHA,IGF1,NKD1,KNDC1,DISP2,IL12A,SLC6A17,INSM1,ITPKA,KCND2,KIF5A,LSS,MAP6,MBP,KITLG,MPP2,ADAM22,MSR1,MYCN,MYT1,HNRNPM,NEFM,NEFH,NELL2,NFIX,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,PKM,KCTD15,FXYD1,PURG,NECAB2,PPP2R2B,LRRN3,VSTM2L,PRKACB,MAPK3,MAPK9,SLC26A11,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRH,PTPRN2,TUG1,TMEM255A,ACSS3,SH3TC2,IQSEC3,SUSD4,RET,PRRT2,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,RTN1,STX1B,S100B,SMPD3,KIF27,PPM1E,ST6GAL1,CCDC92,SLC6A8,SLC8A1,ARFGAP1,OGDHL,RCOR3,SNAP25,SNCA,FAIM2,USP33,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,SPTAN1,SST,NKAIN2,ADHFE1,NECAB1,SYNE2,SYP,ANKRD12,MCF2L,PDLIM2,SATB2,ZEB1,GPRIN3,FRYL,VWCE,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TIMP4,RELL2,ASXL3,TPM1,DOK6,TTC3,CLHC1,KCNK12,ZNF184,DPYSL5,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,SLC17A7,ITM2C,RGS7BP,FAM13C,HNRNPA3,GJC2,ACTR3B,DPF3,ST8SIA2,SPATA13,JPH3" Drug ctd:D002737 Chloroprene CTD 6.01E-14 2.64E-09 3.29E-10 3.71E-09 244 1355 "FMNL2,KLHL32,CCDC85A,PWWP2A,MTUS1,PCDH19,NME5,AMPD2,AMPD3,CDC42BPA,SEMA7A,APBB2,EPB41L5,APOC2,SHROOM2,ARNTL,ASGR1,MARCH3,STK33,SLC4A4,ATP2B2,NRP2,PROM1,IL33,CH25H,SPAG9,RUNX1T1,CBR1,KRIT1,USP2,CD38,CDH2,LARGE1,ZNF445,CDO1,LRWD1,NOG,UBE2L6,SRSF11,CBARP,FAM189A2,ABCG2,HECTD1,MAP4K4,LY86,CCDC151,CNR1,ARMC8,MYRIP,ZNF521,ZFP28,NECTIN3,RBM39,AKAP12,NCOR1,CRYM,LRRC3B,IPCEF1,DZIP3,PHF14,CTH,PUM1,CYBB,DOCK4,HDAC9,KATNAL2,GAPVD1,RIPOR2,DGKG,DAPK1,PITPNC1,ARMCX2,RHOBTB1,SV2B,NR1D2,CPEB2,CASP8AP2,DTNA,EBF1,WDPCP,EDNRB,HIPK3,RASGRP1,KLHL5,TMTC1,FAM13A,PHF20L1,EGFR,EGR3,KCTD3,EIF4G1,EIF5,PLEKHA1,SRPK3,ELN,CALCRL,EPB41,NCALD,ETV1,RASL12,F5,TMEM132C,DLC1,FCGR1A,ZMYND10,BAIAP2,MEX3B,HPCAL4,FOXF2,IQCG,FOXO3,EVL,SEMA4D,FLT1,TMEM107,AK8,CAMKK2,ST6GALNAC3,FYB1,SDCBP2,GALNT15,MTHFD2,GFRA2,PCDH17,PPARGC1A,LYVE1,GLUL,ZNF638,GPT2,LILRB4,GPD2,GPR34,PRDM5,FAM107A,GUCY1A1,TOX2,LRRC75A,IRF8,IFI16,IGF1,KNDC1,IL12A,ITGAM,LMO2,PIK3AP1,MAT2A,MBD1,MEF2C,KITLG,MN1,MYCN,NEK1,NFIX,NRCAM,PCSK1,PCSK5,GNG2,PFKFB3,ABCB1,CCSER2,GPSM2,PCDH18,PILRA,SH3KBP1,MINDY2,LRRN3,PRKCB,PRODH,GDPD1,MASP1,SAMD9,GDPD2,QRICH1,PTPRD,PTPRE,PTPRO,MARCH1,FAT4,RBBP6,RGS4,PBRM1,ZFHX4,SETD5,ROBO2,ZC3H14,MEG3,KCNIP3,CLIP1,SATB1,ATXN7,TNFRSF19,SLA,PREX2,PKNOX2,RADIL,TET1,SMARCA4,LIMCH1,FAM126B,PDZRN3,TSNAXIP1,SOX11,SPP1,ZC3H13,TROVE2,POGZ,SAMSN1,ANKRD12,MCF2L,ADGRL3,WSCD1,TCF4,SZT2,ARHGAP9,HIF3A,CDH22,ARL10,THRA,TIAM1,TIMP4,ERCC6L2,ZNF346,SYNPO2,TRIO,TRPS1,TTC3,UBE2H,UBE3A,UCHL1,VAV1,TSPAN11,RBFOX3,WNT7A,EMSY,MFF,DNALI1,PRDM8,TMEM178A,MDH1B,PLD4,KAT6A,FBXO36,ZDHHC20,ST8SIA2" Drug ctd:D008694 Methamphetamine CTD 7.48E-14 3.28E-09 3.64E-10 4.10E-09 251 1407 "RALGAPA1,NDRG3,ADCY6,ADD2,ADORA1,ADORA2A,ADRA1B,ADGRF5,SRPX,CARNS1,LTBP4,AMPD3,BIN1,EP400,CDK10,ARHGDIA,ARRB2,ATP1A1,ATP2A2,ATP6V0A1,MYOM1,TTLL9,ADAM15,BARD1,BID,PROM1,LDHD,DST,SYNJ2,BAIAP3,CA4,CACNA2D1,CACNB4,LURAP1,CALB2,SPAG9,ARHGEF25,CBR1,CCK,P2RX6,ARHGEF1,ARHGEF2,LRRFIP1,LARGE1,MAGI1,DIS3L,ASIC3,TAOK2,NDST3,ABCG2,FAM19A5,CNR1,PICK1,CNTFR,C2CD2,CREM,ANKRD44,NCOR2,GDA,CRYM,CS,CSF1,ARHGEF10,PDE4DIP,PUM1,RIMS2,PPP6R2,GPSM1,CYBB,HDAC9,RIPOR2,ZFYVE16,LIN54,IST1,DGKG,IP6K1,LYPD1,ZC3H11A,DMD,DNM1,DMPK,DPYSL2,RASGRP1,EBI3,RASA4,EIF4G2,RGS17,SRPK3,PCOLCE2,USPL1,ENO2,MFSD10,RASGRP2,ENPP6,SRRM1,NCALD,SPEG,HSPA12B,SH3YL1,TUBA1B,STRADA,PPP1R1B,FGFR3,ATP5PD,FLNC,FLT1,SYT3,FYN,GABRG2,MTHFD2,SYT17,CPLX2,CPLX1,WASHC2A,GFRA2,PPARGC1A,RAB30,TNRC6A,ZNF638,CBX1,POLL,PRUNE2,GRIA2,SPACA9,GRIN2D,GRM2,NXPH3,ATXN2L,BACH2,GABARAPL2,AGBL5,IDH3A,KNDC1,TJAP1,FAM69A,KCNB1,KCNJ5,LAMP2,STMN1,PIK3AP1,MAP2,MAP4,MAPT,MBP,MIA2,MN1,MOV10,COL28A1,NRBP2,TAGLN3,LYRM9,MYO7A,MYT1,IDNK,NFE2L2,NPY,NPTX2,OGG1,OPRL1,OXTR,TREM2,PCSK1,PDE4B,PDE4D,PDE1B,PFKFB2,ABCB1,PIK3R1,XRN1,PKM,PLCD1,PLEC,SMOX,ANKRD16,PSAT1,PILRA,MINDY2,PPP3CA,PRODH,SNRK,PTH1R,RGS4,RPL15,CLIP1,SBF1,SEC14L1,SGK1,CPEB3,MYO18A,FUZ,SLC4A3,SLC2A5,LIMS2,SLC6A8,SIRT2,TRIM67,LGI3,ZFP1,OGDHL,SMARCD3,SNCA,FAM126B,SPTAN1,CAMTA2,ITPRID2,THSD1,SSTR2,MPRIP,PHLDB1,SEPT3,NECAB1,JMJD6,SUPT5H,PRRC2C,ARC,SYN2,SYP,ASTN2,EXOC7,ALG1,TCF4,NEU4,SYNE1,OBSL1,TNS2,ARHGAP9,DICER1,ZMAT3,TK2,CSMD1,PARD3,CABIN1,TNS1,PIK3R5,TUBB2A,SGK3,UBC,UCHL1,PLPPR2,VGF,VLDLR,ZIC2,ZNF142,ZNF189,DPYSL5,ANKS1B,EMSY,ADAMTS9,PCBP4,MPPE1,KAT6A" Drug 3873_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.13E-13 9.32E-09 9.32E-10 1.05E-08 56 175 "ABHD6,NME5,ALCAM,SRPX,APLP1,ADGRB2,BMP7,ST3GAL5,GYG2,RAB29,SYNGR3,CLGN,LHX2,WHRN,AKAP12,PDE4DIP,ARMCX2,OPTN,ENO2,RASGRP2,FYN,STON1,GPR37,SYNPO,KCNB1,MPP2,MXI1,PCBP3,TMOD2,SERPINI1,RETREG1,LRP12,GRAMD1C,PRPH,PTPRH,FAM184A,SH3GL3,ASAP3,CPEB3,ST6GAL1,ARHGEF40,NMNAT2,ELOVL4,RGL1,STXBP1,TRIM2,SYNE1,HEY1,BEX4,RUNDC3B,UCHL1,ZNF45,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 6934_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-13 1.17E-08 1.07E-09 1.20E-08 60 196 "SEMA6A,LTBP4,ALDH7A1,BMP7,SCAPER,RAB29,SYNGR3,ARHGEF10,GREB1,GAPVD1,BRINP1,DBN1,ARMCX2,CDON,OPTN,SUGP2,EPB41L2,F8,ARMCX1,FGFR1,FYN,SYT17,MALT1,RUNDC3A,GPR37,ELOVL5,INPP1,KCNH2,KPNA5,MATK,MEIS1,MPP2,PDE4A,PLTP,POLG,MAPK7,PTPRE,ZDHHC14,MAPK12,SEC14L1,SUPT20H,ZFP30,SYBU,ANKRD6,SLC6A8,SNCA,KDM4B,ZHX3,IQSEC2,ELOVL4,STX1A,PLCB1,SIK3,TMPO,PLPPR2,VLDLR,REEP1,EMSY,KCNAB1,RNF170" Drug 5076_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-13 1.92E-08 1.60E-09 1.80E-08 60 198 "ASPHD1,ASIC1,AMPD3,AMT,SEMA7A,APOC1,SEMA4G,MARK4,ADAM23,ADGRB2,MTMR3,CACNA1I,CACNA1G,CACNA1A,CAPN3,RUNX1T1,SLC16A4,WHRN,AKAP5,SH2B1,HAPLN1,VCAN,RIMS2,FAM131B,HEPH,EIF4G2,COQ7,MTSS1L,KAT8,FAM49B,PCDH17,CSDC2,CACFD1,MAN2A2,MATN3,ADAM22,NF1,NOVA1,PPARA,LRRN3,MAPK10,WDR25,PTH1R,PTPRB,PID1,SLA,PKNOX2,SLC11A1,OGDHL,ZHX3,DDN,SPART,ATP10B,PHLDB1,KIAA1107,AP4E1,SLC44A1,CHST5,SEMA3B,KCNAB1" Drug ctd:D020245 p-Chloromercuribenzoic Acid CTD 4.73E-13 2.07E-08 1.60E-09 1.80E-08 176 909 "ASPHD1,ASIC1,PLEKHH1,BEND6,SEMA6A,PCDH10,CDC42BPA,CDC14B,ARRB1,CCDC74A,TMEM108,KIF1A,BCHE,ZNF599,JAZF1,CA4,LURAP1,CALB1,THSD7A,CARS,DGKI,NOG,SLIT2,LHX2,RAB33A,NRXN3,TPP1,ABCG2,FAM149A,SLC4A8,ZNF521,IGDCC3,NSL1,CREM,HAPLN1,SNCAIP,LRRC3B,FAM169A,CTH,ZSCAN23,PYGO1,SPOCK2,MFAP3L,CHRDL1,CPEB2,EBF1,KLHL5,PHF20L1,EGFR,PLXNC1,LINC-PINT,TMEM35A,EPHB1,NCALD,CEP85L,F5,FDFT1,FECH,SYNCRIP,TMEM107,STAMBP,GABRB3,ERAP1,IGSF5,ADAM28,RAB40B,LNX1,PRDM5,ZHX1,FRMD3,ATXN2L,MIER3,HSPA1L,CELF5,EID2B,SHISAL1,ZIC5,LIFR,SFXN5,NCOA7,MAP6,MATK,EFHB,MKLN1,MT1M,LAYN,NEXMIF,NDP,NEFM,NELL2,NF1,NFE2L2,NPTX1,PAX6,PCDH8,PCSK1,SLC10A4,PFKFB2,PIK3C2A,SLC25A23,PCDH18,ING3,PPP2R2B,PRKCB,EPDR1,GRAMD1C,VPS13C,PTN,STK32A,PTX3,TMEM231,MARCH1,RET,REV3L,RFX2,PRIMA1,KLHDC8A,ROBO2,RORB,ARMH4,SPIN3,SARS,SCN7A,SCN8A,TNFRSF19,GALNT10,HSPA4L,ARX,CHD9,FHOD3,CNKSR2,DHX30,PKNOX2,SLC6A8,ARHGEF40,COA1,FAM219A,PDZD2,SPP1,NFASC,LMO3,ITPRID2,SST,SOX21-AS1,ARHGEF9,EXOC7,NR2F1-AS1,WSCD1,SATB2,SYNE1,PCDHB7,OBSL1,SLC35G2,HIF3A,ZFPM2,ARL10,CBX5,FAM124A,RGMB,RUNDC3B,TRO,TSC2,RPRM,FAM155A,UCHL1,CCDC136,VGF,LMF1,RBFOX3,ZIC1,SPIRE1,TUBA1A,TMEM178A,PCBP4,KAT6A,MSRB3" Drug ctd:C523799 MRK 003 CTD 8.84E-13 3.87E-08 2.77E-09 3.12E-08 155 775 "ACTN1,AXIN2,BBOX1,CDC42BPA,EPB41L5,CPNE5,SHROOM2,TMEFF1,RGS20,ADAM15,BCL7A,ST3GAL5,WASF1,IL33,CAST,CH25H,CD86,CDH2,CHN1,ARHGAP22,NGEF,FAM189A2,CNN3,CNR1,AKAP7,FAM149A,CDC42BPB,ABCG1,RGS6,LRIG1,SOCS5,PLXNA4,PITPNM3,CTH,ARHGEF4,SCRN1,ARMCX4,ARMCX2,SACS,FAM107B,DMD,HEYL,EBI3,EMX2,EPB41,ERBB2,SIRPB1,FAM198B,TBC1D16,FCGR1A,FCGRT,OLFM1,FGF13,MEX3B,FLNC,FOLR2,SPECC1,TRIM16,RASL10A,DLL3,MEGF11,MEGF10,CPLX1,GATM,PPARGC1A,RUNDC3A,NTNG2,KCNMB4,FERMT2,GPT2,LILRB4,GPD2,PRUNE2,SPACA9,SERP2,GSN,RNF165,FRMD5,FRMD3,BACH2,VSIG4,ZDHHC15,CPT1C,IFI16,ZIC5,RBPJ,IL6R,KCND2,KIFC3,LMO2,KITLG,MSR1,NRBP2,MYCN,MYO6,IDNK,NEFM,TREM2,SMOX,PCDH18,PLXNB1,PMP22,LRP12,EPB41L4B,PILRA,PPP2R2B,PKIA,PTN,ZIK1,ACSS3,BEND5,RGS4,LGI2,ROBO1,FBXW7,ZNF671,S100B,FHOD3,SLC2A5,SLC12A2,ELMO2,TET1,CXXC4,SNAP25,SNCA,PDZRN3,SOX11,SPP1,MIR100HG,PHLDB1,MCF2L,TRIM2,PCDHGB2,PCDHB7,CHST8,CDH22,HEY1,TIMP4,NPL,RGMB,TST,UCHL1,CLIP2,ZNF23,EMX2OS,NDRG4,TCEAL7,CELF4,LAMP5,NAV3,RGS7BP,DOCK8,NLRP3,NHSL1,SPATA13" Drug ctd:D004113 Succimer CTD 1.15E-12 5.05E-08 3.27E-09 3.68E-08 228 1278 "ACHE,NDRG2,AGT,ALCAM,BBOX1,AMPD3,CDC42BPA,SEMA7A,FGD2,APOC2,PPFIA3,USP37,SEMA4G,CASK,CADPS,PDE8B,PTCH2,N4BP2L1,BCL7A,NRP2,BLM,CFLAR,FUBP1,SCAPER,JAZF1,CACNA1A,CACNA1B,CAPN3,CAST,SPAG9,USP2,SLC16A4,CD86,CBFA2T2,ZNF445,CDO1,UBE2L6,CHN1,LHX2,NRXN3,CLTC,HECTD1,ARHGEF6,NECTIN3,RBM39,ANKRD44,GDA,ABCG1,CSF1,PDE4DIP,CST3,DZIP3,CTH,RIMS2,CYBB,HDAC9,ZFYVE16,RASSF2,TBC1D5,MATR3,AIF1L,ZNF804A,MFAP3L,ZC3H11A,DDX46,ALKBH8,SACS,MTX3,DMPK,NR1D2,CASP8AP2,PDCD6IP,RCAN1,ARRDC4,EDIL3,WDPCP,EEF1D,PHF20L1,EGFR,MBNL2,EGR3,ENO2,EPB41L2,ERBB4,IGSF6,ANKMY1,TLR7,FAM198B,ACSL4,PRAM1,ST3GAL6,FCGR3A,SLC9B2,FGF1,SYNCRIP,ZMYND15,SMC2,PDLIM5,FAM49B,TRIM16,ZNF605,MPP6,FYN,ERAP1,ALDH1L1,SESN1,ADAM28,MALT1,BRD8,HPGDS,ZNF638,GNG4,GPD2,MCHR1,GSN,KAT7,GUCY1B1,RASSF8,TOX2,PADI2,IFI16,IGF1,NKD1,SCIN,IL6R,IL6ST,ITGAM,JAK2,KIFC3,KIT,STXBP5,LIG4,LIMS1,SYTL4,LSS,PACRG,SMAD9,GPR155,AQP11,MEF2C,MID1,MOV10,LAYN,NFE2L2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,SETD4,PDE4B,ENPP2,GPR85,ABCB1,SERPINI1,PIK3R1,ZFYVE21,SLC25A23,STRN3,PILRA,MINDY2,TATDN3,PRKCB,SPDL1,ZIK1,TUG1,USP47,RBBP6,RBBP8,ZDHHC14,REV3L,RNASE1,NUDT11,ZFHX4,RPS6KA2,HUNK,RTN1,CHD9,ST6GAL1,LIMS2,ZNF430,SLC8A1,CCDC88A,SLC11A1,SLC22A4,FAM126B,SPP1,KDM4C,ZC3H13,ZBTB43,RBM26,TROVE2,STAC2,SULF2,SYN1,ANKRD12,TCF4,TRIM2,TCF12,NSD1,SIK3,AKTIP,SLC44A1,TLR4,TMPO,PRRT1,NR2C2,PDSS1,STXBP4,TRPS1,TTC3,USP1,MGAT5B,VLDLR,WIPF1,AGMO,AMZ1,EVI5,FIP1L1,FAM13C,RTN4,HNRNPA3,JMJD1C,NLRP3,TTC7A,ADAMTS10,SPATA13,SENP7" Drug 6653_UP Bezafibrate [41859-67-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-12 5.23E-08 3.27E-09 3.68E-08 59 197 "ASPHD1,ASIC1,ADD2,FAM135A,APBB2,CFLAR,FUBP1,BAIAP3,CA4,CACNA1A,SCARB1,NCOR2,PDE4DIP,CNTNAP2,DTNB,DUSP9,SNX29,SEMA3D,ING4,TNK2,IGSF6,ETV1,F5,REEP2,OLFM1,FLT1,AFF2,OGA,FYB1,GCK,SRCAP,STMN2,ITGA7,KCNB1,KCNJ5,MAP2,ADAM22,NELL2,OGG1,PALM,GPR85,PFKFB2,DUSP26,RETREG1,NLE1,TMEM231,CCDC40,KIRREL1,FBXW7,SCN2B,FRMPD1,SNCA,PHLDB1,SYT5,HIF3A,R3HDM1,PARD3,KCNAB1,DPF3" Drug CID000004376 N-methyl-DL-aspartic acid Stitch 1.40E-12 6.13E-08 3.60E-09 4.06E-08 136 655 "ACHE,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,LRFN2,BEGAIN,AMT,APBA2,APLP1,DDO,CASK,BCHE,CACNA1I,CACNA1G,CA4,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,CAMK2A,CAMK2B,CAMK2G,RHBDL1,CCK,KRIT1,LRBA,CDH2,MAGI1,DLGAP1,CACNA2D2,ASIC3,CHRNA4,CNR1,PICK1,AKAP5,NRG2,CREM,BOC,ARHGAP32,MATR3,DAPK1,DBI,DBN1,GRIN3A,SHANK1,DTNB,EIF4G2,ENO2,GPHN,STX2,ERBB4,ADGRV1,NRN1,PTK2B,PPP1R1B,BAIAP2,AGAP2,SYT3,FOLH1,CAMKK2,NSG1,FYN,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,INPP5K,NTNG2,TTBK1,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,GUCY1B1,KCND2,KCNJ16,CAMK2N2,MAP2,MAP4,ADAM22,NPY,NPR2,NTRK2,NTRK3,OPRL1,PIK3C2A,PIK3R1,PKD1,GPSM2,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,PRODH,RELN,PTCH1,PTK2,PTN,ENOX1,RASGRF1,RASGRF2,GLDN,RYR3,SALL1,NLGN1,CPEB4,SST,JMJD6,ARC,SYN2,SYP,TACR1,TPCN2,TIAM1,ICAM5,CABIN1,TRIO,SLC30A3,SLC17A7,NETO2,NETO1" Drug 3226_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-12 8.40E-08 4.67E-09 5.26E-08 59 199 "SYN3,ABHD6,SEMA6A,SEMA7A,PPFIA3,SEMA4G,PRX,ATP6V0A1,BMP7,ST3GAL5,CA4,SLC16A4,ARHGEF1,CNTN1,SNCAIP,SIPA1L1,CYBB,DCAF8,MFAP3L,EXOG,RCAN1,EGFR,PLXNC1,ING4,RASGRP2,FHL1,IQCG,PRELID3A,SIGLEC8,GFER,ADAMTS13,INPP5B,ITGA7,KCND1,KCNN1,MATN3,NTRK2,PDE1C,LRP12,MBOAT7,RGS12,ZFHX4,SUGCT,KLHDC8A,ASAP3,PEX26,SLC6A8,BTBD7,SLC22A4,TSNAXIP1,HECW1,SAMSN1,SMG6,ICAM5,TNS1,LAT2,SLC30A3,DNALI1,FAM13C" Drug ctd:D006220 Haloperidol CTD 2.36E-12 1.03E-07 5.30E-09 5.97E-08 85 344 "ADCY5,AXIN2,ADORA2A,AP2A2,OSBPL8,ATP1A1,ATP1A3,ATP1B3,RGS9,CACNA1A,CAMK2A,CAMK2B,CCK,DCLK1,NUMBL,CHN1,RAB28,CLTB,ABCG2,QKI,CRHBP,CST3,DRP2,EDN1,RASGRP1,ERBB2,ERBB4,PPP1R1B,HPCAL4,SYT3,CAMKK2,FYN,CHL1,GABRB3,GAD1,GLUL,MCHR1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,HMGCR,KCNH2,MAP2,MBP,NPY,NPTX2,OPRL1,CLDN11,PDE4A,PDE1B,ABCB1,SERPINI1,PKM,PPM1B,PPP1R1A,PPP3CA,PPP5C,PRKACB,PRKCB,MAPK3,MAPK9,RELN,WBP1L,RASGRF1,RGS4,RORB,KCNIP3,STX1B,SGK1,SNAP25,STX1A,ARC,SYN2,SYPL1,TRIM2,THRA,UGT8,VLDLR,VSNL1,MAP3K12,KCNAB1,RTN4" Drug 5460_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.42E-12 1.06E-07 5.30E-09 5.97E-08 59 200 "AMT,APC,PPP4R4,RGS20,PLA2G4C,BAIAP3,STOML1,SULT4A1,LY86,CRMP1,ARHGEF4,EGFR,ING4,ELN,C3orf18,ERCC2,IGSF6,RRAGB,OLFM1,HPCAL4,NSG1,SEPT9,NEU3,GDF9,GFER,GNAO1,VSIG4,KCNB1,KCNQ3,MAP4,MAPT,MEF2C,MGAT3,ADAM22,TAGLN3,MYCN,ZNF862,NOVA2,PRKAR1B,MAPK10,RELN,RFX2,RGS12,ZFHX4,TCP11L1,FAM214B,SLC11A1,SNCA,ZNF423,ARHGAP26,SPTAN1,ATP10B,JMJD6,ARC,DICER1,UCHL1,XRCC4,MKRN3,ZNF154" Drug 6507_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.54E-12 1.11E-07 5.30E-09 5.97E-08 58 195 "ASIC1,AGT,AK2,PPP4R4,MARK4,SLC4A4,KSR1,LDLRAD4,CFAP410,CA4,USP2,ARHGEF1,SCARB1,PLEKHB1,LHX2,HOMER3,CABP1,CYBB,RCAN1,DTNA,PLXNC1,TENM1,VPS26C,DLC1,DCTN2,PCDH17,RUNDC3A,GNAL,GPER1,GRM8,GSTM5,KIF5A,MATK,MBD1,ADAM22,RETREG1,PLCD1,NECAB2,LRRN3,PPP5C,WDR25,ELOVL2,RGS3,SBF1,PREX2,ARHGEF40,SNCA,DDN,ST5,ARC,ADGRL3,IQCE,TRIM2,DOCK9,PCDHA5,TNS1,XRCC4,ADAMTS9" Drug 3994_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.06E-12 1.78E-07 8.08E-09 9.10E-08 58 197 "N4BP2L1,BCHE,BMP7,SYNJ1,SCAPER,SLC16A4,CBFA2T2,ARHGAP33,DLGAP2,TPP1,RAB26,AKAP7,RIMS2,MYEF2,DRP2,DUSP9,CELSR3,SUGP2,PLXNC1,IRAK4,ZNF391,PRELID3A,OGA,GALC,ERAP1,NEU3,SRCAP,PCDH17,GNAO1,ICA1,IL12A,KIFC3,KIT,NF1,NPR2,NTRK2,POU6F1,PTPRN2,GAL3ST4,CRTAC1,TCP11L1,RPS20,KCNIP1,SEMA6D,CSRNP3,ZNF821,MRAS,SH3BP2,ANKRD6,SOX15,IZUMO4,COBL,EXOC7,RPGRIP1L,CRTC1,CDK20,VGF,ZNF24" Drug 4826_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.42E-12 2.82E-07 1.13E-08 1.28E-07 58 199 "TRMT9B,BIN1,EPB41L5,GAS7,SPTBN4,RGS20,CDK13,MARK4,GYG2,HAP1,KRIT1,CD86,CLGN,SOCS6,QKI,NRG2,RIMS2,DCAF4,DAPK1,SPOCK2,GSDME,EDN1,CDKL3,PIPOX,ANKMY1,RRAGB,F5,AGAP2,AFF2,ERAP1,MALT1,LYVE1,GPER1,ICA1,JAK2,KCNB1,MGAT3,TAGLN3,NCAM2,CNOT4,NPTX1,LRP12,PPP5C,RELN,C1orf54,SLC25A36,KIF13A,PDZD2,ZC3H13,RBM26,THSD1,NXT2,ARC,WSCD1,RPGRIP1L,CABIN1,TNS1,TUBB1" Drug 4297_DN Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.42E-12 2.82E-07 1.13E-08 1.28E-07 58 199 "LTBP4,OGT,APC,RASL11B,MYRF,CFAP410,CACNA1A,CAMK2B,PLEKHB1,B4GALT6,WHRN,CPS1,PDE4DIP,DZIP3,MAML1,C2CD2L,PLPPR4,RCAN1,DTNA,HIPK3,NCALD,FGFR1,ANKFY1,ERAP1,SYT17,SRCAP,GPD2,SOX21,DHX35,HSF2,ICA1,KCNB1,LIG4,ADAM22,ZNF862,NF1,OCRL,PALM,PLXNB1,CEP41,GRAMD1C,PREX2,BTBD7,KIF13A,ZHX3,ZBTB43,TROVE2,THSD1,PHLDB1,SMG6,SYNE1,TNS2,CABIN1,VIPR2,ZBTB14,SPHK2,MAP3K12,EMSY" Drug ctd:C410127 PCB 180 CTD 6.46E-12 2.83E-07 1.13E-08 1.28E-07 281 1683 "ABR,ACTN1,ADCY5,USP31,TEX22,ADRA1B,ADGRF5,SEMA6A,SPOP,ARHGAP20,AMH,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,ASPA,CCDC74A,PTCH2,ZBTB10,NUMB,TMEM108,ATP2B2,N4BP2L1,ATP6V1G2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,RUNX1T1,PRC1,CCK,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN1,CHN2,PLEKHB1,LHX2,NRXN3,COX4I1,NSL1,CLOCK,ENTPD4,C1QL2,CSF1,ARHGEF10,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,HDAC4,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,SGSM2,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,PLXNC1,TMEM132E,PLEKHA1,ENO2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,NSRP1,RPS6KC1,PTK2B,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,FGFR3,MEX3B,HPCAL4,AGAP2,ZMYND15,FLT1,SMC2,CAMKK2,CELF1,TPPP3,GAA,GALNT15,GABRG2,ZNF274,DISC1,SRRM4,TUBA8,CYP46A1,GFRA2,CSDC2,RUNDC3A,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,MAP7D2,GNAL,PRUNE2,GPR37,CNTRL,GRIN2C,ATE1,ZNF496,RNF165,GSTT2,ZBTB49,BVES,HAS2,HNF4G,IGFBPL1,DHX35,MYLK2,SOWAHA,IGF1,NKD1,KNDC1,DISP2,INSM1,ITPKA,KCND2,KIF5A,MAP6,MPP2,ADAM22,MSR1,MYCN,MYT1,NEFH,NELL2,NFIX,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,KCTD15,FXYD1,PURG,NECAB2,PILRA,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRN2,TUG1,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,SMPD3,MRAS,PPM1E,ST6GAL1,SLC6A8,SLC8A1,ARFGAP1,OGDHL,RCOR3,FAIM2,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,SST,NKAIN2,ADHFE1,NECAB1,SYNE2,PLCB1,SYP,ANKRD12,MCF2L,PDLIM2,KLHL4,SATB2,ZEB1,GPRIN3,FRYL,VWCE,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TIMP4,RELL2,ASXL3,TLR4,TPM1,DOK6,CHST5,TTC3,CLHC1,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,SLC17A7,RGS7BP,FAM13C,GJC2,ACTR3B,ST8SIA2,SPATA13,JPH3" Drug ctd:C009407 "2,5,2',5'-tetrachlorobiphenyl" CTD 1.11E-11 4.86E-07 1.87E-08 2.10E-07 281 1691 "ABR,ACHE,ADCY5,USP31,TEX22,ADRA1B,ADGRF5,SEMA6A,SPOP,ARHGAP20,AMH,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,ASPA,CCDC74A,PTCH2,ZBTB10,NUMB,ATP2B2,N4BP2L1,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,RUNX1T1,PRC1,CCK,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN2,PLEKHB1,LHX2,NRXN3,COX4I1,NSL1,CLOCK,ENTPD4,C1QL2,RGS6,ARHGEF10,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,ARHGEF4,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,ALKBH8,SACS,SPOCK3,SGSM2,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,PLXNC1,TMEM132E,PLEKHA1,ENO2,APC2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,NSRP1,RPS6KC1,PTK2B,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,ATP5PD,MEX3B,HPCAL4,AGAP2,ZMYND15,FLT1,SMC2,CAMKK2,CELF1,GAA,GALNT15,GABRG2,ZNF274,DISC1,SRRM4,CPLX1,TUBA8,CYP46A1,GFRA2,CSDC2,RUNDC3A,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,MAP7D2,GNAL,PRUNE2,GPR37,CNTRL,GRIN2C,ZNF496,RNF165,GSTT2,ZBTB49,BVES,HAS2,HNF4G,IGFBPL1,DHX35,MYLK2,SOWAHA,NKD1,KNDC1,DISP2,IL12A,INSM1,ITPKA,KCND2,KIF5A,KIFC3,LSS,MAP6,MPP2,ADAM22,MSR1,MYCN,MYT1,NEFH,NELL2,NFIX,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,KCTD15,SMOX,FXYD1,PURG,NECAB2,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRN2,TUG1,TMEM255A,ACSS3,SH3TC2,IQSEC3,SUSD4,RET,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,SMPD3,MRAS,PPM1E,ST6GAL1,SLC8A1,ARFGAP1,OGDHL,RCOR3,FAIM2,SPATA7,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,NKAIN2,ADHFE1,NECAB1,SYNE2,PLCB1,SYP,ANKRD12,MCF2L,PDLIM2,SATB2,ZEB1,GPRIN3,FRYL,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TMEM9,TIMP4,RELL2,ASXL3,TPM1,DOK6,TTC3,CLHC1,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,SLC17A7,RGS7BP,FAM13C,KAT6A,HNRNPA3,GJC2,ACTR3B,DPF3,ST8SIA2,SPATA13,JPH3" Drug 4821_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.66E-11 7.27E-07 2.54E-08 2.87E-07 53 177 "NME5,CDC14B,ST3GAL5,SCAPER,CACNA1G,BAIAP3,USP2,CLGN,AKAP7,NECTIN3,CPS1,AKAP12,PDE4DIP,ARMCX2,TMCC2,OPTN,FAM13A,RASGRP2,PTK2B,FYN,CYP46A1,STON1,PCLO,RNFT2,MXI1,NEK1,PCDH9,SERPINI1,PLCD1,PRPH,SH3GL3,ASAP3,ST6GAL1,SYBU,WDR47,FAM214B,PKNOX2,ARHGEF40,CCDC88A,SOX15,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,RPGRIP1L,HEY1,NPL,RUNDC3B,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 7381_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.68E-11 7.38E-07 2.54E-08 2.87E-07 57 198 "AMPD3,AMPH,CDC42BPA,APC,CDC14B,DNAH17,CFLAR,LDLRAD4,CALB2,CAMK2B,CPS1,VCAN,DBT,RUSC2,DPH1,DTNA,DUSP9,FCF1,ING4,FGFR1,BAIAP2,SEMA4D,FYB1,ALDH1L1,GLYR1,GNAO1,KCNF1,MMP16,MYO7A,OGG1,CLDN11,PALM,GPR85,PLCD1,PRKAR1B,TMEM104,TMEM231,ZNF671,MAPK12,TRA2B,FUZ,KANSL3,SMARCD3,RBM34,KDM4C,PHLDB1,PLCB1,TCF4,TRIM2,SLC44A1,CABIN1,AMACR,VIPR2,WNT7A,ZNF711,UBE3B,TIGD6" Drug 4071_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.68E-11 7.38E-07 2.54E-08 2.87E-07 57 198 "SYN3,ADCY6,DOC2A,APC,CDC14B,PRX,SLC2A11,BCHE,RGS11,BMP7,SCAPER,GYG2,CAMK2B,ARHGEF2,NRXN3,VAX2,NRG2,CSF1R,LRIG1,RIMS2,SEC14L5,DMPK,DTNA,SEMA3D,NCALD,AGAP2,PRELID3A,DISC1,PCDH17,POLL,TPPP,CACFD1,GSTM5,ADAM22,NF1,NTRK2,PLCD1,PTCH1,PTN,PTPRD,GAL3ST4,RNASE1,PBRM1,GSTCD,SLA,PKNOX2,ZNF334,ARHGAP26,SPTB,RBM26,ARC,SYT5,MCF2L,GPR161,TNS1,CHST5,JPH3" Drug ctd:C069837 fullerene C60 CTD 1.85E-11 8.08E-07 2.70E-08 3.04E-07 254 1501 "VWA5B2,ASIC1,ACHE,XKR4,GALNT16,ADD1,AXIN2,PLEKHH1,ADORA1,PWWP2A,ADRA1D,ADRA1B,SLC24A4,AP2A1,HECW2,C1QTNF1,PCDH10,AMPD2,LRFN1,OGT,SEMA7A,FGD2,APBA2,GAS7,PRX,ARNTL,ARSE,ASGR1,MARCH3,DNAH17,PTCH2,ATP1B3,ATP6V0A1,RGS11,GPR146,ARHGEF7,AP1M1,CACNA1I,CACNA1G,IL33,CALB2,KALRN,HIP1R,USP2,CBFA2T2,CDC25B,DCLK1,ARHGAP33,CRLF1,FAM189A2,QKI,WHRN,AHCTF1,NRG2,CDC42BPB,C2CD2,SH2B1,CRY2,CRYBB1,NCOR1,GDA,CLIP3,CRYM,CSF1R,SUSD5,PDE4DIP,ARHGEF4,GPSM1,KIF26A,DGKB,DCTN1,C2CD2L,RHOBTB1,SGSM2,TMCC2,SLC29A4,NR1D2,CDON,SLC12A6,CASP8AP2,DTNB,TOM1,DUSP9,DNM1L,EDN3,PHC2,TMTC1,KMT5B,RGS17,ELN,PAN3,RASGRP2,APC2,PIPOX,TLR7,HSPA12B,ARMCX1,CLVS1,CHST15,BAIAP2,AGAP3,FOXO3,FLT1,AKAP3,FAM49B,TRIM16,NSG1,ABLIM2,FAM120B,GHDC,TMEM8B,CPLX2,SRCAP,GPR162,PCDH17,PPARGC1A,MSL3,GNAL,PRRC2B,GP1BB,STMN2,GRB10,GRIN2D,ATE1,CIT,GSTM5,ZBTB49,MUM1,MAN1B1,ATXN2L,ELOVL5,HMGCL,CFAP126,HSPA1L,CELF5,IDH3B,MYLK2,IGF1,ITGA7,ITGAM,KCNN3,KIFC3,IPO5,TTYH2,MAP6,AQP11,MBP,MYH3,MYO7A,NELL2,NFIX,NINJ2,CNOT4,NPY,NTRK3,OGG1,PAX6,CDK18,PDE4D,PDE1B,GNG2,CYTL1,PGAM2,NLGN3,XRN1,PLTP,PURG,PDZRN4,RETREG2,MBOAT7,IRX1,PPP5C,PRKACB,PKIA,PRKAR1B,MASP1,BCAS3,DEF8,STK32A,RIPOR1,SH3TC2,RASGRF1,DUSP15,PRRT2,RFX3,RGS3,RGS12,SETD5,KIRREL1,RYR3,S100B,SEMA6D,SEC14L1,MRAS,TRA2B,COPZ1,RASA3,SH3BP2,SH3GL3,ST6GAL1,SYBU,SLC2A5,EPN2,KANSL3,SLC6A8,SLC8A1,SLC14A1,SLC22A4,SMARCA4,OGDHL,SNAP25,FAIM2,PDZD2,SPP1,KDM4C,DBNDD2,ZBTB43,LMO3,THSD1,SSTR2,TTBK2,STAC2,ADHFE1,SEPT3,KLHL7,PLCB1,SYN1,TACR1,MCF2L,TAL1,WSCD1,TCF4,SATB2,SYNE1,PCDHB3,HIF3A,CCDC173,MTMR14,RELL2,BHLHB9,TNS1,CHST5,SMUG1,LRRC24,TRIO,UBTF,OSBP2,CCDC136,WNT7A,ATP6V0E2,ZNF142,ZBTB38,MEIS3,AAAS" Drug 5065_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.10E-11 9.22E-07 2.98E-08 3.35E-07 53 178 "ADRB2,MTUS1,APAF1,SHROOM2,CDC14B,ARNTL,MARK4,NRP2,ST3GAL5,HIP1R,USP2,WHRN,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,PTK2B,TAOK3,BAIAP2,FYN,STON1,TPPP,FAM69A,ITGA7,KCNB1,KCNH2,LIFR,MAP2,MAPT,MMP16,ADAM22,NTRK2,PCDH9,PDPK1,SERPINI1,RETREG1,PRPH,PTCH1,PID1,ENOX1,RGS4,FBXW7,SH3GL3,ASAP3,KDM4B,DOP1A,ARHGAP26,ELOVL4,RGL1,SYT1,COBL,SLC17A7" Drug 7480_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.62E-11 1.15E-06 3.48E-08 3.92E-07 57 200 "KDM5D,SEMA6A,GAS7,FAM131A,PPP4R4,CDK13,MARK4,MTMR3,CFAP410,CALB2,CAMK2G,SYNGR3,TAOK2,CREM,DZIP3,TBC1D5,MFAP3L,EXOG,DNM1,CNNM1,MRNIP,EZH1,ACSL4,SRCAP,USP19,GLYR1,RAB30,GRIN2C,RNFT2,TJAP1,MAP4,MEIS1,MIA2,NELL2,NF1,NOVA1,SERPINI1,PLCD1,PRKAR1B,PRPH,RIPOR1,CEP97,CCDC25,RPS6KA2,SPTAN1,STX1A,IQCE,KIAA0930,SZT2,CRTC1,PLPPR2,XRCC4,ZNF45,NDRG4,TFIP11,SEMA3B,UBE3B" Drug 4006_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.62E-11 1.15E-06 3.48E-08 3.92E-07 57 200 "BEGAIN,BIN1,SEMA7A,APBB2,APC,PPP4R4,CDK13,ADAM23,NRP2,BMP7,CLDN10,CBFA2T2,CACNA2D2,CNTN1,ARMC8,CREM,ENTPD4,SEC14L5,SPOCK2,MFAP3L,EXOG,DTNA,HIPK3,TENM1,EPHB1,ZNF391,ZNF589,OGA,SIGLEC8,GRIK5,IL6ST,JAK2,KITLG,MMP16,CNOT4,NPY,NLE1,PLCD1,C1orf54,BEND5,CARF,RTN1,ASAP3,FUZ,OGDHL,SNCA,SPTB,MCF2L,ADGRL3,KLHL4,CHST8,R3HDM1,CDK20,VGF,VIPR2,PHTF2,AP3B2" Drug 3564_UP Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.50E-11 1.53E-06 4.51E-08 5.08E-07 56 196 "ASIC1,ADORA1,SEMA7A,KCNAB2,EPB41L5,CFLAR,CA4,CACNA2D1,ARHGAP33,CLGN,FOXN3,CRMP1,OSBPL3,RIMS2,CDON,EDNRB,EGFR,MBNL2,TENM1,VPS26C,NRN1,ABCA8,AFF2,NSG1,GPER1,ITGA7,KCNB1,KHK,ADAM22,MYO7A,NF1,NTRK2,OPRL1,PDE4B,PRKAR1B,PRODH,PTPRN2,ZNF493,NUDT11,PNMA8A,SEMA6D,CPEB3,CNKSR2,SNCA,SPP1,ARHGAP26,CDK19,ARC,CUX2,CHST8,GPR161,NR2E1,WIPF1,KLC2,NT5M,KCNAB1" Drug 6276_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.23E-11 1.86E-06 5.30E-08 5.97E-07 53 181 "ABHD6,NME5,APAF1,MARK4,BMP7,ST3GAL5,SCAPER,CACNA1G,RAB29,CLGN,CACNA2D2,PDE4DIP,ARMCX2,OPTN,MBNL2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,RNFT2,PADI2,INPP5B,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,RETREG1,PKIA,PRPH,RPS6KA2,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,CCDC88A,THSD1,ELOVL4,RGL1,STXBP1,KIAA0930,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,NDRG4,REEP1,SLC30A3,SLC17A7" Drug ctd:D058185 Magnetite Nanoparticles CTD 4.74E-11 2.08E-06 5.77E-08 6.50E-07 228 1326 "NDRG2,AGT,ALCAM,BBOX1,AMPD3,CDC42BPA,SEMA7A,FGD2,APOC2,PPFIA3,USP37,SEMA4G,CASK,CADPS,PDE8B,PTCH2,N4BP2L1,BCL7A,NRP2,BLM,CFLAR,FUBP1,SCAPER,JAZF1,CACNA1A,CACNA1B,CAPN3,CAST,SPAG9,USP2,SLC16A4,CD86,CBFA2T2,ZNF445,CDO1,UBE2L6,CHN1,LHX2,NRXN3,CLTC,HECTD1,ARHGEF6,NECTIN3,RBM39,ANKRD44,GDA,ABCG1,CSF1,PDE4DIP,CST3,DZIP3,CTH,RIMS2,CYBB,HDAC9,ZFYVE16,RASSF2,TBC1D5,MATR3,AIF1L,ZNF804A,MFAP3L,ZC3H11A,DDX46,ALKBH8,SACS,MTX3,DMPK,NR1D2,CASP8AP2,PDCD6IP,RCAN1,ARRDC4,EDIL3,WDPCP,EEF1D,PHF20L1,EGFR,MBNL2,EGR3,ENO2,EPB41L2,ERBB4,IGSF6,ANKMY1,TLR7,FAM198B,ACSL4,PRAM1,ST3GAL6,FCGR3A,SLC9B2,FGF1,SYNCRIP,ZMYND15,SMC2,PDLIM5,FAM49B,TRIM16,ZNF605,MPP6,FYN,ERAP1,ALDH1L1,SESN1,ADAM28,MALT1,BRD8,HPGDS,ZNF638,GNG4,LILRB4,GPD2,MCHR1,GSN,KAT7,GUCY1B1,RASSF8,TOX2,PADI2,IFI16,IGF1,NKD1,SCIN,IL6R,IL6ST,ITGAM,JAK2,KIFC3,KIT,STXBP5,LIG4,LIMS1,SYTL4,LSS,PACRG,SMAD9,GPR155,AQP11,MEF2C,MID1,MOV10,LAYN,NFE2L2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,SETD4,PDE4B,ENPP2,GPR85,ABCB1,SERPINI1,PIK3R1,ZFYVE21,SLC25A23,STRN3,PILRA,MINDY2,TATDN3,PRKCB,SPDL1,ZIK1,TUG1,USP47,RBBP6,RBBP8,ZDHHC14,REV3L,RNASE1,NUDT11,ZFHX4,RPS6KA2,HUNK,RTN1,CHD9,ST6GAL1,LIMS2,ZNF430,SLC8A1,CCDC88A,SLC11A1,SLC22A4,FAM126B,SPP1,KDM4C,ZC3H13,ZBTB43,RBM26,TROVE2,STAC2,SULF2,SYN1,ANKRD12,TCF4,TRIM2,TCF12,NSD1,SIK3,AKTIP,SLC44A1,TLR4,TMPO,PRRT1,NR2C2,PDSS1,STXBP4,TRPS1,TTC3,USP1,MGAT5B,VLDLR,WIPF1,AGMO,AMZ1,EVI5,FIP1L1,FAM13C,RTN4,HNRNPA3,JMJD1C,NLRP3,TTC7A,ADAMTS10,SPATA13,SENP7" Drug 4358_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-11 2.37E-06 6.24E-08 7.03E-07 56 198 "NDRG2,ADORA1,AGT,LTBP4,FAM135A,TRMT9B,SEMA7A,APBA2,GAS7,AZGP1,ADGRB2,CHN2,COL9A3,MYRIP,CRMP1,DUSP9,AASS,EPB41,EPHB1,ERBB4,SPEG,APC2,CSPG5,GABRG2,ERAP1,GATM,ALDH1L1,GLI2,LILRB4,ATXN2L,HLF,KCND2,KPNA5,MAN2A2,MSR1,TAGLN3,NPTX2,PCSK5,ENPP2,PLCD1,PLTP,PLXNB1,LRRN3,ENOX1,ZNF493,PEG10,ZNF423,WSCD1,SYNE1,DOCK9,DNAH7,ICAM5,TNS1,UCHL1,LAT2,KCNAB1" Drug 5763_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-11 2.37E-06 6.24E-08 7.03E-07 56 198 "AMPD3,SEMA7A,APAF1,BCAS1,PRX,CFAP410,CALB2,CAMK2B,DLGAP2,RAB26,WHRN,NRG2,PHF14,ARHGEF4,MFAP3L,C2CD2L,DTNA,CELSR3,ING4,DENND4A,PDLIM5,POLL,ATXN2L,ELOVL5,TJAP1,KCNN1,KHK,LAMA2,LMO2,MEF2C,TAGLN3,P2RX7,PGAM2,PIK3R1,CEP41,MAPK10,PTN,ZSCAN32,PTPRN2,MARCH1,ENOX1,RFX2,STUM,SUPT20H,PPP4R3A,TAL1,PCDHGA10,SLC44A1,TPM1,RPRM,UCHL1,FLRT2,NDRG4,SPHK2,SEMA3B,SLC17A7" Drug 4477_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-11 2.56E-06 6.55E-08 7.38E-07 55 193 "APAF1,APBB2,CDC14B,ARRB1,ARSE,CDK13,ATP1A3,NRP2,CFLAR,CBS,NRXN3,ABCG2,RAB26,HOMER3,WHRN,COL9A3,AKAP5,NCOR2,CSF1,DUSP9,SEMA3D,TENM1,ELN,ZNF391,ETV1,KAT8,FAM49B,ZNF44,SRCAP,GPER1,CNTRL,GRIK5,JAK2,KCNN2,SMAD1,ADAM22,PDE4B,GPR85,MINDY2,MAPK7,SNRK,ELOVL2,PTPRB,CCDC40,RFX2,RGS3,KCTD17,SLC11A1,DOK5,ZHX3,EXOC7,TBL1X,TNS1,TRO,KCNAB1" Drug ctd:C015001 arsenite CTD 6.15E-11 2.69E-06 6.73E-08 7.58E-07 283 1732 "KCNH8,SYN3,AS3MT,KDM5D,NDRG2,ADCY8,AXIN2,RNF150,ADRA1B,ADRB2,SLC24A4,ZNF608,TAOK1,SEMA6A,CDC42BPA,ANK2,MAGEE2,PHYHD1,RGS20,CADPS,ZSCAN18,PCDHGB4,RASL11B,ZNF582,ZNF583,BACH1,RGS9,ST3GAL5,FUBP1,DDR1,CALM1,KALRN,SPAG9,CBLN1,CLDN10,CCK,USP2,CD86,DGKI,CDC25B,CDH2,LRRFIP1,CDO1,CCPG1,LHX2,CNTN1,CABP1,RTTN,MYRIP,ZFP28,FAM171B,CRHBP,ANKRD44,NCOR2,VCAN,PDE4DIP,SLITRK5,PPP1R16B,ERC2,PLCXD3,CTH,CCDC144A,RASSF2,LONRF1,MAML1,DAPK1,BRINP1,ELMO1,KLHL3,GSDME,SNAP91,FAM107B,DLX1,GRIN3A,DMD,DMPK,DNAH9,DYNC1I1,DOCK2,DTNA,FAM78B,KRBA2,EBF1,EDN1,SEMA3D,TMTC1,EGFR,EGR3,PLXNC1,EIF4G1,ENO2,LRRC17,EPHB1,ERCC2,ANKMY1,CD320,NRN1,ARMCX1,DLC1,RACK1,CHST15,ZMYND10,SPSB4,FGF12,BAIAP2,FOXF2,SYNCRIP,FOXO3,SEMA4D,FOLH1,NBEA,ERGIC3,GABRG2,ACSS1,CPLX2,GCNT2,PCDH17,GHR,LOXL3,GNAO1,GNG4,GPT2,LNX1,GPD2,GPR37,TMEM121B,STMN2,GRIA2,ZNF496,CIT,CLASRP,FAM19A2,FAM107A,MUM1,IRAK3,HAS2,FRMD3,HNMT,ZDHHC15,IGF1,NKD1,RBPJ,IL12A,INSM1,LRRTM1,ITGA7,KCNN2,LAMA2,STMN1,LIFR,MARK1,AQP11,TM6SF1,SHC3,MEIS2,MEST,SCAMP5,MMP17,PTOV1,TAGLN3,MYCN,LAYN,MYT1,NCAM2,NCF2,NEFM,NFE2L2,ALDH1L2,NPY,NOVA1,NPTX2,NTRK3,OGG1,CLDN11,OXTR,P2RY1,PAX6,PCDH8,PCDH9,PCSK1,PDPK1,PIK3R1,GPSM2,IRX1,PKIA,SKOR1,PRKCB,MAPK3,MAPK7,MAPK9,MAPK10,PRPH,RELN,LAMA1,PTCH1,ELOVL2,ZIK1,PTPRE,PTPRG,PTX3,TMEM255A,ACSS3,RASGRF2,RGS3,PNMA8A,RORB,EPHA10,SALL1,SEMA6D,LRFN5,SCN2B,SCN7A,FNIP1,HSPA4L,SH3GL3,ARX,TRIM67,ZNF334,NAPB,ZNF667,GKAP1,SNAP25,MAPKBP1,SNCA,PDZRN3,SOX3,SOX11,DOK5,NMNAT2,DBNDD2,LMO3,SST,SSTR1,PLCB1,SYT1,TACR1,ANKRD12,TAL1,TBCEL,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA2,PCDHB7,PCDHB6,PCDHAC2,PCDHA3,SIRT1,CHST8,GALNT17,TIAM1,ICAM5,TLR4,NR2E1,TMPO,PARD3,PIK3R5,PDSS1,TRO,RPRM,UCHL1,UGT8,FLRT2,MGAT5B,VLDLR,VSNL1,ZNF781,ZIC1,KCNT2,NDRG4,LYPD6,TCEAL7,CELF4,ZNF154,LAMP5,PRTFDC1,PRDM8,VPS35L,DOCK8,FRMD6,NETO1,ST8SIA2" Drug 4377_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.30E-11 3.64E-06 8.87E-08 9.99E-07 56 200 "RALGAPA1,NME5,LTBP4,DOC2A,BIN1,CDC42BPA,GAS7,APLP1,PPP4R4,CFLAR,SCAPER,SGCE,CACNA1I,LDLRAD4,CALB2,CRLF1,CNTFR,WHRN,CSF1,HIPK3,ING4,RASGRP2,OLFM1,FGFR3,SEMA4D,TRAF3IP2,DISC1,ALDH1L1,PCDH17,TDRKH,RASSF8,MAP2,TM6SF1,MIA2,MID1,PLXNB1,STRN3,LRP12,RGS12,GSTCD,TCP11L1,SEC14L1,SLC9A5,MAPKBP1,TMCC1,JMJD6,PLCB1,SMG6,KIAA0930,ZEB1,CRTC1,THRA,TNS1,RUNDC3B,GDPD5,EPM2A" Drug ctd:C009618 "O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate" CTD 8.58E-11 3.76E-06 8.95E-08 1.01E-06 58 211 "SYN3,ACHE,SEMA6A,ALK,DOC2A,APLP1,APOC1,PPFIA3,ATP2B2,BCHE,NRP2,BID,CACNA1B,SLC25A14,NOG,CPNE6,CNR1,CNTFR,RIMS4,PLXNA4,ERC2,DCTN1,DPYSL2,FIS1,SEMA3D,TENM1,EPHB1,ACSL4,FGF11,FGF14,ATP5PD,SEMA4D,CSPG5,SDCBP2,GRM2,CPT1C,IL12A,NEFM,NEFH,NF1,ABCB1,NLGN3,SEMA5B,RELN,RET,ARX,NLGN1,ZNF423,SPTB,NFASC,VPS13A,SYN1,SYN2,SYT1,PPIL6,WNT7A,DPYSL5,MFF" Drug 4000_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-10 6.03E-06 1.36E-07 1.53E-06 55 197 "RALGAPA1,ADD2,ADORA1,NME5,ALK,AMT,SEMA7A,PPFIA3,MADD,CDK13,ADAM15,FUBP1,BAIAP3,CBFA2T2,SCARB1,TPP1,MYRIP,ENTPD4,CRY2,PDE4DIP,PHF14,SEC14L5,DTNA,HIPK3,SRPK3,SPEG,ETV1,OGA,HLF,IL12A,KHK,KIFC3,MMP16,NF1,PURG,PPARA,MAPK10,ELOVL2,PTPRN2,BEND5,GAL3ST4,RGS4,RPS20,SH3BP2,SNCA,KIF13A,PHLDB1,MCF2L,EXOC7,TNS1,TPM1,ZNF24,PARP11,PHTF2,DPF3" Drug 6650_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-10 6.03E-06 1.36E-07 1.53E-06 55 197 "RALGAPA1,ADRA1D,SYT13,BEGAIN,ANK2,APAF1,CDC14B,PPP4R4,ZSCAN18,ADGRB2,MPDZ,BMPR1B,KALRN,CBFA2T2,ABCG1,RIMS2,DAPK3,DBT,RUSC2,ING4,IGSF6,DLC1,OLFM1,FLT1,NEU3,GNAO1,SPACA9,KCNJ5,KCNQ3,SMAD9,AFF1,NEFM,NRCAM,RETREG1,C19orf57,MAPK10,ZSCAN2,CCDC40,KCTD17,FBXW7,SLA,SLC11A1,SNCA,HECW1,ARHGAP26,MCF2L2,SPART,ATP10B,SYN2,COBL,TACR1,LAT2,ZNF74,SPHK2,EVI5" Drug 4349_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-10 6.10E-06 1.36E-07 1.53E-06 52 181 "NME5,ALCAM,MARK4,N4BP2L1,ST3GAL5,RAB29,USP2,CLGN,AKAP12,ARMCX2,TSPAN5,OPTN,RASGRP2,STX2,HPCAL4,FYN,STON1,NXPH3,MX1,MXI1,MYCN,PDE1C,PDE4A,TMOD2,PGAM2,SERPINI1,RETREG1,PLCD1,PRPH,PTCH1,FAM184A,SH3GL3,PPM1E,ASAP3,CPEB3,FAM214B,ARHGEF40,CCDC88A,SSTR2,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,ICAM5,TNS1,RUNDC3B,SSBP2,UCHL1,REEP1,SLC30A3,SLC17A7" Drug ctd:C081766 "2,4,4'-trichlorobiphenyl" CTD 1.55E-10 6.81E-06 1.48E-07 1.67E-06 241 1437 "ABR,USP31,TEX22,ADGRF5,SEMA6A,SPOP,AMH,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,ASPA,CCDC74A,PTCH2,ZBTB10,ATP2B2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,PRC1,CCK,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,CHN2,PLEKHB1,NRXN3,COX4I1,NSL1,ENTPD4,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,SGSM2,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,PLXNC1,TMEM132E,PLEKHA1,ENO2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,AGAP2,ZMYND15,FOXO3,FLT1,SMC2,CAMKK2,CELF1,GAA,GALNT15,GABRG2,ZNF274,DISC1,SRRM4,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,MAP7D2,GNAL,PRUNE2,GPR37,CNTRL,GRIN2C,ZNF496,RNF165,GSTT2,ZBTB49,BVES,HAS2,HNF4G,IGFBPL1,MYLK2,SOWAHA,NKD1,KNDC1,DISP2,INSM1,ITPKA,KCND2,KIF5A,MAP6,ADAM22,MSR1,MYCN,MYT1,NEFH,NELL2,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,KCTD15,FXYD1,NECAB2,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRN2,TUG1,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,SMPD3,PPM1E,ST6GAL1,SLC8A1,ARFGAP1,OGDHL,RCOR3,FAIM2,FNBP1,SOX11,NMNAT2,TEX2,ARHGAP26,NKAIN2,ADHFE1,NECAB1,SYNE2,SYP,ANKRD12,MCF2L,PDLIM2,SATB2,ZEB1,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,MTMR14,TIMP4,RELL2,ASXL3,DOK6,TTC3,CLHC1,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,RGS7BP,FAM13C,ACTR3B,ST8SIA2,SPATA13,JPH3" Drug 1490_UP Diflunisal [22494-42-4]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-10 7.44E-06 1.58E-07 1.78E-06 55 198 "NME5,C1QTNF3,SPARCL1,BIN1,CDC42BPA,KCNAB2,CDC14B,PLA2G4C,ALDH7A1,CFLAR,KSR1,SCAPER,AKAP7,RIMS2,GPRASP1,ARHGAP24,MBNL2,PTK2B,ZNF589,FGFR1,BAIAP2,HPCAL4,PDLIM5,OGA,TRAF3IP2,SEPT9,SRCAP,PCDH17,PRUNE2,HNMT,INPP5B,LMO2,MBD1,MEF2C,MSI1,ZNF862,NPTX2,SETD4,NLE1,PLCD1,PRODH,FRMPD1,ASAP3,PEX26,FAM214B,SLC11A1,SNCA,DOK5,ANKRD12,WSCD1,PCDHGA10,CRTC1,CHST8,PIK3R5,VIPR2" Drug 5017_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.74E-10 7.61E-06 1.59E-07 1.79E-06 52 182 "ABHD6,LTBP4,APLP1,DNAH17,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,WHRN,ARMCX2,TMCC2,FRY,OPTN,TBC1D16,CORO2B,BAIAP2,FYN,CYP46A1,AHDC1,STON1,KCNH2,MAP2,MITF,MPP2,MXI1,NEK1,NPY,PDE4A,SERPINI1,PRPH,PTCH1,RPS6KA2,SH3BGR,SH3GL3,ASAP3,WDR47,FAM214B,CCDC88A,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,SMG6,TRIM2,HEY1,RUNDC3B,SLC30A3,GDPD5,SLC17A7,PLSCR4" Drug 3993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.86E-10 8.15E-06 1.66E-07 1.87E-06 51 177 "ABHD6,ADRB2,MTUS1,SHROOM2,CDC14B,ARNTL,MARCH3,ST3GAL5,HIP1R,CBFA2T2,WHRN,ABCG1,PDE4DIP,CTH,RIPOR2,PLPPR4,RGS17,RASGRP2,TAOK3,BAIAP2,NBEA,FYN,CYP46A1,PCDH17,STON1,GUCY1B1,FAM69A,ITGA7,KCNH2,MEF2C,TAGLN3,PCDH9,ENPP2,SERPINI1,RETREG1,PRPH,PTCH1,RGS4,SH3GL3,ASAP3,WDR47,KDM4B,ARHGAP26,CEP68,RGL1,SYT1,COBL,TNS1,TRIM9,SLC30A3,PLSCR4" Drug CID000000611 glutamate Stitch 2.13E-10 9.34E-06 1.87E-07 2.10E-06 174 962 "ASIC1,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,SEMA6A,SYT13,APLP1,DDO,ASPA,SLC4A4,ALDH7A1,RIPK1,BCS1L,CACNA1I,CACNA1G,CA4,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,CAMK2B,CBS,KYAT1,CCK,KRIT1,CD38,LRRFIP1,DLGAP2,CDO1,CACNA2D2,ASIC3,CHRNA4,CLCN3,SULT4A1,HOMER3,CNR1,PICK1,NRG2,CPS1,CREM,SH2B1,GDA,CS,PLCXD3,EARS2,DAPK3,GRIN3A,SLC25A18,DTNB,AASDH,AASS,EIF4G2,ENO2,GPHN,NRN1,PTK2B,PPP1R1B,AGAP2,FOLH1,CSPG5,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,DISC1,INPP5K,CPLX2,GCK,TUBA8,GGT7,GGT5,TCERG1,COPS8,GLUL,GPT2,GPD2,STON1,MCHR1,GRIA2,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,ATE1,GRM2,GRM8,CIT,GSTT2,ATXN2L,IDH3A,IDH3B,IGF1,NKD1,KCND2,KCNJ16,LIG4,PACRG,MAP2,MAP4,MAPT,MAT2A,KITLG,NEFM,NFE2L2,NPY,NTRK2,NTRK3,OPRL1,P2RX7,P2RY1,ABCB1,PKD1,PKM,GPSM2,PLCB2,PLCD1,PLEC,PSAT1,PPP3CA,PPP3CC,PRKCB,MAPK3,MAPK10,PRODH,PRPH,PRPSAP2,RELN,KLK6,APTX,PTK2,RYR3,S100B,MAPK12,SGK1,SHMT2,SLC6A11,IFT122,SNAP25,NMNAT2,SPP1,ERC1,NFASC,SST,STX1A,PLCB1,SYN1,SYN2,SYP,SYT1,TACR1,MLST8,ACTR6,BHLHB9,CABIN1,NPL,TRPM2,SGK3,UBC,VGF,SLC30A3,SLC38A1,SLC17A7,PLD4,NETO2,JPH3" Drug 4464_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.48E-10 1.09E-05 2.13E-07 2.40E-06 53 189 "ASIC1,APC,ARRB1,ADGRB2,ST3GAL5,GYG2,CFAP410,SYNGR3,CRLF1,CHN2,RAB33A,WHRN,AKAP5,NCOR2,ABCG1,VCAN,PDE4DIP,FAM131B,EDN1,REEP2,SCARA3,FYN,GLI2,TDRKH,STON1,GPR37,ITGA7,KCNH2,LIFR,OXTR,PALM,PIK3R1,GRAMD1C,PRPH,PTCH1,RGS4,SH3GL3,FRMPD1,ASAP3,ARHGEF40,ELOVL4,ARC,SYT1,COBL,KLHL4,TCF4,SZT2,OBSL1,THRA,TNS1,CDK20,NDRG4,ZNF225" Drug 1674_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.57E-10 1.13E-05 2.16E-07 2.44E-06 55 200 "ADRA1D,AMH,AMPD3,ARHGDIG,MARK4,ATP2A2,CFAP410,CA12,ZMYM4,SLIT2,RAB28,SH2B1,ARHGEF4,CDON,COQ7,BAIAP2,SEMA4D,CGREF1,ERAP1,GCNT2,TXNL4A,GNG4,SLC2A6,ATXN2L,IL6R,KCNJ5,MAP4,MBOAT7,PPP3CC,PRKAR1B,MAPK7,PRPH,ELOVL2,PTN,RAD51D,RGS12,TCP11L1,SLA,BTBD7,SMARCD3,TSNAXIP1,KDM4C,CEP68,PLCB1,SYN2,SYT5,SMG6,TRIM2,TRIO,VAV1,LAT2,ZNF45,NDRG4,KCNAB1,PHTF2" Drug 5277_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.81E-10 1.23E-05 2.28E-07 2.57E-06 54 195 "ABHD6,NME5,AK2,SRPX,LTBP4,APC,GAS7,PDE8B,GYG2,KYAT1,SYNGR3,ARHGEF2,FOXN3,LHX2,HOMER3,CNTNAP2,GREB1,ARHGEF4,RASSF2,EXOG,EDNRA,EGFR,ING4,HSD17B14,FGF12,INPP5K,PCLO,ICA1,IL6ST,KIF5A,LMO2,MPP2,ZNF862,GPR85,PRODH,GTDC1,RGS3,RGS12,ZFHX4,ANKRD6,SLC6A8,SLC9A5,MAPKBP1,TROVE2,ARC,MCF2L,RPGRIP1L,PLPPR2,VAV1,ZNF23,REEP1,GDPD5,MPPE1,EPM2A" Drug 5977_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.81E-10 1.23E-05 2.28E-07 2.57E-06 54 195 "SHROOM2,ADGRB2,ST3GAL5,SYNJ2,CACNA1I,SYNGR3,ARHGAP33,RAB28,ABI3BP,ABCG1,PDE4DIP,CNTNAP2,EXOG,DTNA,EDIL3,HIPK3,FCF1,SEMA3D,MBNL2,EIF5,RGS17,ERCC2,DLC1,FLT1,GAD1,POLL,TDRKH,GPR37,CNTRL,PADI2,LSS,MMP16,NFYA,PCDH9,RETREG1,MAPK7,TMEM104,CARF,GSTCD,NEK11,ST6GAL1,BTBD7,SPTB,LHPP,SYT1,ASTN2,OBSL1,ZFPM2,TMPO,R3HDM1,LAT2,SPHK2,NAV3,GAN" Drug ctd:D014638 Vanadates CTD 3.44E-10 1.51E-05 2.67E-07 3.01E-06 221 1303 "NCKAP5,KDM5D,ZNF608,OSBPL6,SRPX,ARHGAP20,PCDH10,FAM135A,ALK,GPRASP2,SEMA7A,APBA2,APBB2,NT5C3B,PPP4R4,CASK,STK33,ZBTB10,SLC4A4,RNF182,ADGRB2,BBS2,NRP2,ST3GAL5,JAZF1,GYG2,C5,GPC2,CA4,CA12,CAMK2B,VXN,CAST,KYAT1,LDB2,CHN1,ABCG2,COL4A5,ABI3BP,ZNF385A,LRIG1,SUSD5,SIPA1L1,PYGO1,DOCK4,HDAC9,GAPVD1,RASSF2,MYEF2,CDON,CPEB2,DPYSL2,RCAN1,MAMLD1,E2F5,EDIL3,TSPAN5,CNNM1,RASGRP1,FAM13A,AASS,EPB41,SLC43A2,CEP85L,ETV1,EYA1,EZH1,NSRP1,TAOK3,SCML2,CORO2B,CHST15,FKTN,MED12L,PRKAG2,SEMA4D,FLT1,POMT1,SMC2,PDLIM5,GABRA3,ERAP1,GCK,GLUL,STARD3,KIAA1958,MAP7D2,KCNMB4,GNAL,GNG4,GPT2,GPD1,TDRKH,CNTRL,PARD3B,IRAK3,TOX2,BACH2,HLF,NEGR1,ZNF678,KHK,KIFC3,KIT,L1CAM,STMN1,MARK1,MEIS1,KITLG,MID1,MMP16,MSR1,NCAM2,ZC3H12B,NCF2,NME4,NOVA1,NPR2,GPR137C,ZNF827,PAX6,PRTG,PDE1C,ENPP2,PDPK1,GNG2,TMOD2,PFKFB3,FAM98B,ABCB1,PIK3R1,SNX10,XRN1,NLE1,PLTP,PSAT1,PRKAB2,PKIA,MAPK3,LAMA1,ELOVL2,PTK2,EML5,PTPRE,PTPRG,RIPOR1,ZNF844,PID1,RAD17,SH3TC2,ZNF493,OXR1,RASGRF1,FIGN,RGS4,KLHL11,LGI2,ZNF671,RPS6KA2,MEG3,STX1B,CCDC112,RMI1,CASC3,GALNT10,PPM1E,FERMT1,CHD9,CCDC92,ANKRD6,ABLIM3,SLC2A5,EPN2,FAM214B,ZNF430,SLC8A1,SLC12A4,GKAP1,CDK5RAP2,SNAP25,SNCA,KIF13A,MCF2L2,NFASC,THSD1,SSTR1,ZC4H2,RGL1,VPS13A,SLC37A2,DNMBP,KIAA1107,TCF4,SATB2,ZFP90,PCDHB15,ZNF34,TK2,ERCC6L2,FAM124A,PIK3R5,TSC1,TST,VLDLR,LMF1,XRCC4,ZNF708,ZNF138,STOX2,TUBA1A,SEMA3B,NAV3,URM1,PCBP4,PLSCR4,RGS7BP,FZD3,RSPRY1,NETO2,DPF3,GAN" Drug 5063_UP Diprophylline [479-18-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.45E-10 1.51E-05 2.67E-07 3.01E-06 54 196 "ADORA2A,NME5,SEMA7A,MARK4,ATP1A3,STX16,NRP2,FUBP1,CACNA1I,CACNA1A,HAP1,SYNGR3,RAB28,RAB26,MYRIP,HAPLN1,PDE4DIP,GPRASP1,DTNA,PLXNC1,COQ7,ETV1,FGFR1,AGAP2,CGREF1,OGA,ALDH1L1,TJAP1,LIFR,LSS,MATN3,KITLG,LYRM9,NELL2,GPR85,PFKFB4,LRRN3,MAPK10,GRAMD1C,PTH1R,KCTD17,GSTCD,RASA3,HECW1,DDN,ATP10B,ASTN2,TBCEL,KLHL4,DOCK9,RPRM,WIPF1,GAN,SENP7" Drug ctd:D000447 Aldehydes CTD 3.47E-10 1.52E-05 2.67E-07 3.01E-06 138 720 "VWA5B2,GALNT16,ADRB2,OSBPL6,SRPX,MARCH4,PDZD4,CDK10,SFMBT2,PPP4R4,ARRB1,TMEM108,RNF182,ADGRB1,RGS9,BMP7,BAIAP3,CA4,CCK,DCLK1,CRLF1,ARHGAP22,NGEF,CRYM,CSF1R,CSF2RA,RIMS4,PDE4DIP,ARHGEF4,AIF1L,KIAA0319,LYPD1,ARRDC4,TMTC1,FAM13A,EBI3,MRO,PLXNC1,F5,REEP2,GTF2IRD2,HPCAL4,AGAP2,EFCAB2,NSG1,FYN,GAD1,ALDH1L1,KCNMB4,GNAO1,C1QL4,CIT,LINGO1,GUCY1B1,SLC2A6,TOX2,PADI2,FRMD5,ICA1,NKD1,NIM1K,ITGA7,KCNH2,KCNN1,L1CAM,LMO2,MAPT,CHST6,ADAM11,LAYN,FXYD7,NEFM,NOVA2,NPTX1,SLC11A2,DUSP26,TMEM38A,KCTD15,JAKMIP1,PLIN1,NECAB2,ING3,SEPT4,FA2H,GRAMD1C,SMIM10L2B,PRPH,GDPD1,LAMA1,PTX3,PID1,TMEM255A,FAM184A,RASGRF2,RADX,RET,KLHDC8A,EPHA10,RPS6KA2,MEG3,TNFRSF19,ABLIM3,LIMS2,SLC6A8,MAST1,OGDHL,SNCA,UNC5B,NFASC,SSTR2,ELOVL4,STAC2,SEPT3,ARC,SYN2,CAMTA1,WSCD1,OBSL1,PCDHA3,PCDHA1,ENHO,TIAM1,BEX4,TPM1,NPL,TRO,VAV1,VGF,LMF1,LAT2,CELF4,DPYSL5,SLC30A3,PRDM8,HRASLS,TMEM63C,ADAMTS10,PRRT4" Drug 4764_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.24E-10 1.86E-05 3.05E-07 3.43E-06 54 197 "ALCAM,APLP1,PPFIA3,PLA2G4C,SLC4A4,CFAP410,CA4,TAOK2,QKI,RCHY1,NCOR2,CSF1R,CNTNAP2,USP6NL,TBC1D5,SLC12A6,RCAN1,DTNA,EGFR,ING4,STX2,ST3GAL6,FGFR1,AFF2,GALC,ALDH1L1,GRB10,CACFD1,GRM8,RASSF8,ATXN2L,IL6ST,MEF2C,KITLG,ZNF862,NF1,NPTX1,PDPK1,RETREG1,NLE1,STRN3,LRP12,PPP5C,ZNF423,ELOVL4,PLCB1,TBCEL,SZT2,SYNE1,TNS1,HIRA,SPHK2,EVI5,TIGD6" Drug 6389_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.24E-10 1.86E-05 3.05E-07 3.43E-06 54 197 "C1QTNF3,PKP4,APAF1,APOC1,CDK10,PRX,PPP4R4,PDE8B,DNAH17,ADGRB2,BCHE,SYNJ1,CBFA2T2,ARHGEF2,ARHGAP33,COL9A3,SPOCK2,GIT2,ELN,NCALD,ZNF391,ETV1,CORO2B,PDLIM5,FYB1,SIGLEC8,POLL,GNG4,LILRB4,HSF2,ICA1,KPNA5,MAP2,NF1,PALM,PDE4B,PTCH1,PTPRE,FAT4,RGS12,CARF,FBXW7,HUNK,SLC2A5,PKNOX2,SLC6A11,SLC11A1,UNC5B,SLC35G2,AP4E1,TRIO,NDRG4,SLC17A7,EPM2A" Drug 4438_UP 2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.24E-10 1.86E-05 3.05E-07 3.43E-06 54 197 "ADCY6,AMH,PPFIA4,KCNAB2,ARRB1,PTCH2,N4BP2L1,KSR1,ST3GAL5,FUBP1,CD86,SYNGR3,CACNA2D2,CHN2,TPP1,AKAP5,CRYM,DGKG,BRINP1,SPOCK3,DTNA,MRNIP,ETV1,FGF1,FOLR2,PDLIM5,FYN,CHL1,MSL3,GNAO1,STON1,CACFD1,IRF8,ITGA7,KCNH2,KIFC3,MYCN,CDK18,PDE4A,RETREG1,VPS13C,C1orf54,RNASEL,ZFP2,SUPT20H,LIMS2,RBM34,ATP10B,ELOVL4,SYT1,TCF4,PCDHA6,SLC44A1,CDK20" Drug 5046_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.24E-10 1.86E-05 3.05E-07 3.43E-06 54 197 "ASPHD1,SEMA6A,AMPD3,KCNAB2,BMPR1B,CACNA1I,HAP1,MTMR7,CD86,CACNA2D2,STOML1,RAB26,WHRN,SPOCK2,EDNRA,EDNRB,CNNM1,COQ7,LRRC17,NCALD,SPEG,PTK2B,FGF1,HPCAL4,PRELID3A,SYT17,GLYR1,GRIK5,NXPH3,ICA1,KCNN1,MARK1,MATN3,MX1,P2RY13,NPTX1,PPARA,LRRN3,PRKAR1B,PRPH,RGS12,FBXW7,TCP11L1,SH3BP2,ASAP3,PLCB1,SYT5,SMG6,DOCK9,HIF3A,CHST8,TNS1,REEP1,HRASLS" Drug 6645_UP Glipizide [29094-61-9]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.19E-10 2.28E-05 3.45E-07 3.88E-06 54 198 "ASPHD1,APBB2,ATP2B2,KSR1,CLDN10,ENTPD2,LARGE1,DLGAP2,CHN2,NCOR2,CSF1R,RIMS2,BRINP1,MFAP3L,DUSP9,ING4,RASGRP2,F5,DLC1,ST3GAL6,OLFM1,ERAP1,ICA1,SHISAL1,KCNJ5,KIT,PACRG,ADAM11,MGAT3,MMP16,ADAM22,NOVA2,PDE4B,GPR85,PGAM2,MTRF1L,RIPOR1,TMEM231,C1orf54,FRMPD1,SLA,SLC2A5,PKNOX2,ZNF334,CXXC4,SNAP25,SNCA,SYT5,TACR1,ADGRL3,PCDHGB6,SZT2,SPHK2,DPF3" Drug 5062_UP Imidurea [39236-46-9]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.19E-10 2.28E-05 3.45E-07 3.88E-06 54 198 "ASPHD1,SYN3,ASIC1,NDRG2,APAF1,ST3GAL5,BTK,BAIAP3,CFAP410,SCARB1,AKAP5,HAPLN1,DTNA,COQ7,ERBB4,ETV1,PRELID3A,CYP46A1,GLYR1,SPACA9,GRIK5,GRM8,KCNJ5,KCNQ3,KIFC3,LIFR,MATK,MATN3,MX1,NOVA2,NPR2,NPTX1,NTRK2,PCDH9,RETREG1,PPP2R2B,LRRN3,CEP41,PTPRH,PTPRN2,FBXW7,KCNIP1,ZFP2,STUM,HKDC1,SLC2A5,KDM4B,ADGRL3,KLHL4,TNS1,CA14,VAV1,VGF,ZNF225" Drug 4139_DN Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.19E-10 2.28E-05 3.45E-07 3.88E-06 54 198 "ADORA1,TRMT9B,AMPH,APBA2,PPP4R4,ARSE,ADAM23,RGS9,CFLAR,KSR1,CACNA1I,LDLRAD4,CFAP410,CAMK2B,RUNX1T1,SLC16A4,SCARB1,PICK1,AKAP7,GREB1,DBT,HS3ST2,EGFR,ELN,STX2,FHL1,HPCAL4,ALDH1L1,POLL,LPAR4,PCLO,HAS2,HLF,KCNB1,MAP4,TAGLN3,NELL2,SERPINI1,PLCD1,PTPRO,ZMAT4,ZFHX4,SEMA6D,ASAP3,SLC9A5,BTBD7,PLCB1,TBCEL,PCDHGB6,PCDHA5,RIMBP2,VIPR2,XRCC4,DPF3" Drug 2312_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.19E-10 2.28E-05 3.45E-07 3.88E-06 54 198 "NME5,KCNAB2,ATP6V0A1,MTMR3,GYG2,USP2,AKAP7,ABI3BP,VCAN,CNTNAP2,SPOCK2,HIPK3,ING4,VPS13B,RRAGB,ZNF589,FGF12,FGF13,GCK,GDF9,GNAL,TDRKH,IRAK3,SHISAL1,C2orf72,ITGA7,ITPKA,KCNB1,KCNJ5,LSS,MID1,MMP17,NPR2,PDE4B,PFKFB2,PLTP,PTPRO,CCDC40,KCTD17,ASAP3,SLC6A8,CXXC4,SMARCC2,SPTB,SPART,CLSTN2,ARC,SLC35G2,HIF3A,TRIO,UGT8,FLRT2,SLC17A7,TIGD6" Drug 7365_UP Riluzole hydrochloride; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.19E-10 2.28E-05 3.45E-07 3.88E-06 54 198 "ABHD6,CDC42BPA,KCNAB2,EPB41L5,SHROOM2,MADD,C5,PTBP2,SOCS6,QKI,WHRN,AATK,PARD6A,SPOCK3,CHRDL1,EXOG,DPH1,HIPK3,FCF1,PLXNC1,ELN,COQ7,ETV1,RRAGB,FGF1,FGF13,TRMO,GLI2,CNTRL,IL6ST,LMO2,TM6SF1,TAGLN3,NDP,CLDN11,TMEM104,PTPRN2,RGS4,TRAPPC13,FBXO11,ST6GAL1,ANKRD6,WDR37,KDM4C,ST5,PHLDB1,PLCB1,ZNF34,R3HDM1,ZKSCAN5,XRCC4,KCNAB1,EPM2A,DPF3" Drug ctd:C038939 enzacamene CTD 5.57E-10 2.44E-05 3.64E-07 4.10E-06 41 130 "ACTN1,UNC5A,CASK,NCOA1,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CAMK2B,CACNA2D2,CHRDL1,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,FGFR1,FYN,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,NXPH3,NF1,NRCAM,NTRK2,NTRK3,CNTN3,RELN,ROBO1,STX1B,HES6,NLGN1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug 4770_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.98E-10 2.62E-05 3.85E-07 4.34E-06 50 177 "NME5,APC,MARK4,N4BP2L1,ST3GAL5,CACNA1G,BAIAP3,CLGN,PDE4DIP,SEC14L5,ARMCX2,TMCC2,OPTN,FAM13A,RASGRP2,STX2,FYN,CYP46A1,RAB40B,STON1,PCLO,MPP2,MXI1,NOVA2,NPTX1,SERPINI1,PRPH,NUDT11,SATB1,SH3GL3,FRMPD1,ASAP3,ST6GAL1,SYBU,WDR47,PKNOX2,CCDC88A,SMARCD3,SOX15,ELOVL4,RGL1,STXBP1,EXOC7,HEY1,TNS1,RUNDC3B,NDRG4,SLC30A3,SLC17A7,PLSCR4" Drug ctd:C030370 "2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone" CTD 6.25E-10 2.74E-05 3.92E-07 4.41E-06 75 320 "RALGAPA1,NDRG2,BBOX1,BIN1,ANK2,CASK,MARK4,ATP1B3,MYRF,CALM1,CBR1,PLEKHB1,TPP1,CLTB,QKI,CNTN1,RBM39,LRIG1,CNTNAP2,SLITRK5,DOCK4,MATR3,DBI,YTHDC1,SEZ6L2,EEF1D,APH1A,GOLGA7,TUBA1B,TUBB3,PRKAG2,EVL,CSPG5,GATM,GLUL,PRUNE2,GPR37,STMN2,GSTM5,GUCY1B1,HBA1,IDH3B,MEF2C,NEFM,NOVA1,NTRK2,NTRK3,PCDH8,PCDH9,PFKFB3,SERPINI1,PPP2R5E,PRKACB,PRKCB,PTN,QDPR,CHD9,SNAP25,SNCA,DOK5,SPP1,LMO3,CLASP2,ITPRID2,SEPT8,PLCB1,SYPL1,SYT1,HEY1,TUBB2A,UBC,UCHL1,CLIP2,ZIC1,RTN4" Drug 4008_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.35E-10 2.78E-05 3.92E-07 4.41E-06 54 199 "ADD2,PPP4R4,ADAM23,ADGRB2,CFLAR,BMP7,SCAPER,MAGI1,NRXN3,NRG2,RGS6,DTNA,HIPK3,SEMA3D,ING4,RGS17,FGF14,HPCAL4,AGAP2,PRELID3A,CACFD1,GSTM5,ELOVL5,ICA1,IRF8,IL6ST,IL12A,MAPT,MARK1,MMP16,LYRM9,CNOT4,NOVA2,PCBP3,NLE1,POU6F1,PTCH1,PTN,PTPRN2,BEND5,RGS4,GSTCD,RPS20,ZNF821,SNCA,ZSWIM8,SPTAN1,CDK19,PHLDB1,COBL,ZEB1,FLRT2,VGF,LAT2" Drug 7446_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.35E-10 2.78E-05 3.92E-07 4.41E-06 54 199 "ADD2,ADRA1D,SEMA6A,BIN1,SLC4A4,MPDZ,KSR1,MTMR3,FOXN3,STOML1,CREM,ABCG1,SEC14L5,MFAP3L,OPTN,MRNIP,HSD17B14,OGA,SRCAP,GPER1,GPR37,ADAMTS13,KCNN1,MAP4,MID1,MMP16,NEFM,NF1,NOVA2,PALM,PDE4B,PPP5C,PRKCB,MAPK7,GDPD2,RIPOR1,ZSCAN2,RYR3,ZNF821,ZKSCAN3,SMARCD3,SNCA,TSNAXIP1,IZUMO4,HECW1,ZC3H13,ELOVL4,PHLDB1,VPS13A,CRTC1,VAV1,VSNL1,TFIP11,KCNAB1" Drug 1020_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.99E-10 3.07E-05 4.26E-07 4.80E-06 53 194 "ASIC1,NDRG2,KCNAB2,FAM131A,ARNTL,CDK13,BMP7,ST3GAL5,SCAPER,GYG2,RAB29,KYAT1,ARHGEF2,PDE4DIP,ARMCX2,ZNF804A,EGFR,FHL1,FYN,DISC1,GNG4,FERMT2,STON1,KCNH2,L1CAM,MAPT,MPP2,ZNF862,PRPH,PTCH1,ELOVL2,RIPOR1,FAM184A,RPS6KA2,EMID1,ZNF821,PPM1E,ASAP3,ANKRD6,SLC22A4,LIMCH1,KIF13A,ELOVL4,STXBP1,COBL,PCDHA6,TMEM121,ZNF34,BHLHB9,RUNDC3B,NDRG4,REEP1,MAP3K12" Drug ctd:D007649 Ketamine CTD 7.33E-10 3.21E-05 4.35E-07 4.90E-06 149 803 "NDRG2,GALNT16,CCDC85A,ADCY8,ADD2,PTCHD1,AGT,TMEFF1,SPTBN4,RASL11B,ATP1A1,ATP1A3,ATP6V0A1,DOCK11,ADGRB2,RGS9,BCS1L,FUBP1,SCAPER,CA4,CALB2,CABP7,HAP1,USP2,P2RX6,CD38,CCPG1,PLEKHB1,FAM189A2,RAB26,CNR1,NECTIN3,ABCG1,VCAN,SOCS5,PHACTR3,PHF14,PLCXD3,CYBB,EARS2,RASSF2,C2CD2L,DNM1,DMTF1,FEM1B,ENO2,ERBB4,EZH1,FDFT1,PPP1R1B,FGFR3,BAIAP2,PRKAG2,SCARA3,ATP13A4,GABRG2,GAD1,FAM120B,CYP46A1,SESN1,RUNDC3A,CRCP,GLUL,ZNF638,CBX1,PLCD4,GRIK5,GRIN2C,GUCY1B1,SLC2A6,MUM1,HMGCR,IGFBPL1,CFAP126,IL12A,FAM69A,ITPKA,JAK2,KTN1,PIK3AP1,MAP6,MAPT,MATK,MBP,EFHB,COMMD5,TAGLN3,MYCN,FXYD7,NPY,NOVA2,NTRK2,CLDN11,TREM2,ENPP2,GPR85,ABCB1,PKD1,PLCL1,SMOX,SEPT4,POLG,POLR2F,MAPK3,MAPK7,PTK2,PTPRH,PTPRN,FAT4,RASGRF1,RBBP6,RBBP8,CRTAC1,ZFHX4,S100B,HES6,MRAS,SLC2A5,WDR47,MTERF2,CXXC4,CABCOCO1,SOX11,HECW1,SSTR1,ST5,KLHL7,VPS13A,SATB2,ICAM5,TLR4,TMPO,RASD2,TPM1,METTL3,CLEC2L,PDIA2,WRN,LGI4,POLR3H,LAMP5,INTS3,NAV3,SLC17A7,ITM2C,PLD4,JMJD1C,KLHDC1,SENP7" Drug ctd:D013849 Thimerosal CTD 7.34E-10 3.22E-05 4.35E-07 4.90E-06 205 1198 "CLK4,FMNL2,OLMALINC,OSBPL8,TAOK1,C1QTNF3,SEMA6A,CEP126,FAM135A,PITPNM2,ANK2,EP400,LCORL,PPFIA4,APC,EPB41L5,LGR5,MARK4,KIF1A,DOCK11,ADGRB2,DST,RAB29,PTBP2,SPAG9,CCNT1,CD86,SYNGR3,TBRG4,NOG,CHN2,PLEKHB1,TPP1,FBXO7,HECTD1,IGLON5,FAM149A,ANKRD35,COX4I1,BAG4,IGDCC3,CPS1,PREPL,C2CD2,ANKRD44,CS,SNCAIP,ARHGEF10,CNTNAP2,ARHGEF4,DCAF4,DOCK4,GAPVD1,HDAC4,GIT2,DBN1,SPATA2,HEPH,ELMO1,RUSC2,KLHL3,CPEB2,SEZ6L2,EDNRB,PHF20L1,MBNL2,PLXNC1,EIF4G1,ENO2,STX2,SRRM1,ERCC2,MRPL10,ADGRV1,MRVI1,TBC1D16,ACSL4,KAT8,FER,FGF11,SYNCRIP,SPECC1,SEPT9,CRCP,RAB30,HTATSF1,GNAL,GNG4,TDRKH,PCLO,PARD3B,GRIK5,MAP4K5,RASSF8,TOX2,MIER3,AGBL5,USP51,NEGR1,AGFG1,HSF2,HSPA1L,IFI16,IGF1,GAREM2,RBPJ,ST7-AS1,TMEM240,KHK,TTYH2,LIMS1,SYTL4,HECTD2,LSS,MAP4,MID1,MKLN1,MMP16,PTOV1,MYO5A,MYO6,MYO9A,SFR1,NEFH,NF1,NME4,NTRK3,TMOD2,PFKFB2,PFKFB4,PIK3C2A,ZNF655,SMOX,SLC25A23,MAGEL2,ING3,MBOAT7,PRKAB2,MAPK3,MAPK9,BCAS3,PTK2,EML5,MARCH1,PRIMA1,CCDC82,MRAP2,PLPPR3,RYR3,TRAPPC13,HSPA4L,CPEB3,CHD9,PREX2,SLC8A1,SLC12A2,ATF7IP,SLC22A4,TET1,EPC1,SMARCC2,SNAP25,KDM4B,TRERF1,BDP1,SP4,HECW1,ERC1,RBM26,CLASP2,ITPRID2,LARP4,NKAIN2,PRRC2C,SYNE2,ARC,TAF9,ADGRL3,TBL1X,OBSL1,HIF3A,DICER1-AS1,CBX5,PRRT1,TP53BP1,NR2C2,CA14,TUBB2A,UGT8,USP1,LMF1,RBFOX3,TRIM9,MKRN3,CADM2,SLC38A1,EVI5,NAV3,PDSS2,HRASLS,KAT6A,PHTF2,JMJD1C,SENP7,JPH3" Drug 989_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.68E-10 3.37E-05 4.47E-07 5.03E-06 52 189 "CDC14B,KIF1A,ST3GAL5,SCAPER,GYG2,SGCE,RAB29,KYAT1,SYNGR3,CRLF1,FOXN3,WHRN,ABCG1,PDE4DIP,RASSF2,DBN1,ARMCX2,OPTN,EGFR,ENO2,CSPG5,FYN,ZNF44,SYT17,STON1,SLC2A6,KCNH2,KCNN1,LMO2,MAPT,ZNF862,NPTX1,PALM,PDE4A,PRPH,CNNM2,PTCH1,FAM184A,ZDHHC14,RPS6KA2,RPS20,ZNF821,ASAP3,LIMCH1,STXBP1,TRIM2,PCDHA5,BEX4,CABIN1,VGF,REEP1,MAP3K12" Drug 4639_DN Felbinac [5728-52-9]; Down 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.75E-10 3.39E-05 4.47E-07 5.03E-06 54 200 "DDO,APOC1,CDC14B,SEMA4G,STX16,KIF1A,SYNJ2,SCARB1,PLEKHB1,TAOK2,ABCG2,SLC4A8,CSF1R,TBC1D5,BRINP1,MFAP3L,FCF1,MBNL2,IRAK4,ETV1,RRAGB,IQCG,AFF2,LYVE1,GLYR1,MSL3,GRM8,INPP5B,LIG4,MAPT,NOVA1,PALM,PLCD1,PRKAB2,GRAMD1C,SAMD9,BEND5,KHDRBS2,SCN2B,ZNF821,FRMPD1,SLA,CCDC88A,BTBD7,SMARCD3,SS18,SYT1,ADGRL3,DOCK9,TK2,RIMBP2,TRIO,XRCC4,UPF3A" Drug 4593_UP Ethionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.56E-10 3.75E-05 4.63E-07 5.22E-06 53 195 "ASPHD1,SEMA6A,AMPD3,APC,NRP2,BMPR1B,MTMR3,LDLRAD4,ARHGEF2,DLGAP1,CBARP,RAB28,STOML1,LY86,CABP1,CREM,CSNK1E,PDE4DIP,CNTNAP2,BRINP1,MFAP3L,CHRDL1,FCF1,ING4,ETV1,VPS26C,FGF1,FGFR1,GNG4,GUCY1B1,HLF,MATN3,AFF1,MYO6,NELL2,PDE4D,PPP5C,PRKAR1B,NEK11,SUPT20H,PPP4R3A,PKNOX2,SNCA,KIF13A,IQSEC2,SYNE1,CRTC1,TPM1,WIPF1,SPHK2,SEMA3B,PARP11,FAM13C" Drug 7377_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.56E-10 3.75E-05 4.63E-07 5.22E-06 53 195 "ABR,ASIC1,ADCY6,AMPD3,SHROOM2,RGS20,MARK4,N4BP2L1,PTBP2,KRIT1,SOCS6,QKI,CPS1,GIT2,DBT,ARMCX2,CHRDL1,DPH1,DTNA,COQ7,ETV1,RRAGB,FGFR1,ANKFY1,ATP2C1,ZNF276,CNTRL,SPACA9,SHISAL1,IL6ST,ITPKA,MBP,TAGLN3,RETREG1,PLCD1,ELOVL2,FAT4,ENOX1,CSRNP3,FUZ,DZIP1,DOK5,SPTAN1,SS18,SYT1,ASTN2,IQCE,METTL3,ZKSCAN5,HIRA,XRCC4,UBE3B,RNF146" Drug 5468_UP Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.56E-10 3.75E-05 4.63E-07 5.22E-06 53 195 "BIN1,APC,CDC14B,ALDH7A1,N4BP2L1,CFLAR,USP2,RCBTB2,FOXN3,TAOK2,HAPLN1,DCAF4,HDAC9,GPRASP1,SPOCK2,GIT2,STX2,F5,KAT8,FER,FGFR1,ERAP1,COPS8,NXPH3,C2orf72,INPP5B,KCNJ5,MMP16,GIT1,NDP,NEK1,NELL2,NNAT,NOVA2,PDE1C,PRKAR1B,RPS6KA2,ABLIM3,ELMO2,LIMCH1,HECW1,ZC3H13,LHPP,TROVE2,WSCD1,DICER1,CHST5,TRIO,AMACR,LMF1,ZFP37,ADAMTS9,FAM13C" Drug 7531_UP 0393-0188; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.56E-10 3.75E-05 4.63E-07 5.22E-06 53 195 "ADCY6,ADORA2A,AP2A2,ALCAM,CDC42BPA,APBB2,RASL11B,ATP2B2,SLC2A11,ADAM23,ADGRB2,SCAPER,BAIAP3,CAMK2B,ARHGEF6,CSF1R,DZIP3,SNX29,HIPK3,EGFR,EPHB1,CDKL3,PIPOX,ALDH1L1,RAB30,GNG4,GUCY1B1,HLF,HNMT,IL6R,LSS,MAP2,MAPT,MMP16,NFYA,CNOT4,NPY,NLE1,EMID1,ASAP3,FNDC3A,LIMCH1,KDM4C,UNC5B,CLASP2,SS18,IQCE,WSCD1,PCDHGA10,TRIO,VSNL1,EVI5,SLC17A7" Drug 2865_UP Resveratrol [501-36-0]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.56E-10 3.75E-05 4.63E-07 5.22E-06 53 195 "ASPHD1,ADORA1,ALK,APLP1,PPP4R4,RGS20,PLA2G4C,SCAPER,THSD7A,CDH2,TPP1,CRMP1,SIPA1L1,ERC2,SPOCK2,ARMCX2,SHANK1,HSD17B14,ERCC2,NCALD,BAIAP2,SEMA4D,FYN,ALDH1L1,SRCAP,GPER1,PCLO,HLF,ICA1,MGAT3,AFDN,CDK18,SERPINI1,RPS6KA2,EMID1,ZNF821,FAM214B,PKNOX2,COA1,KDM4B,IQSEC2,SPART,CUX2,SZT2,SLC44A1,TK2,FAM155A,VLDLR,LAT2,SLC30A3,ITM2C,PLSCR4,ADAMTSL3" Drug 5574_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-09 4.58E-05 5.45E-07 6.14E-06 53 196 "AMT,AZGP1,CACNA1I,CBFA2T2,PICK1,WHRN,CRMP1,CSF1R,RIMS2,RASSF2,DAPK1,DMD,SHANK1,AASS,SPEG,DLL3,NEU3,GRM8,GSN,SYNPO,KCNJ5,KCNN2,KIFC3,L1CAM,MAPT,AFDN,TAGLN3,NELL2,NNAT,NTRK3,PDE1C,PLCD1,LRP12,MAPK10,DCHS2,ZMAT4,RFX2,KCTD17,FRMPD1,ASAP3,CNKSR2,DZIP1,SLC2A5,SLC8A1,CXXC4,SPTB,KIAA1107,DNAH7,ICAM5,PIK3R5,CHST5,LAT2,XRCC4" Drug 3720_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-09 4.58E-05 5.45E-07 6.14E-06 53 196 "LTBP4,ALK,SEMA7A,PPP4R4,ZSCAN18,ZBTB10,RASL11B,NRP2,BMP7,BAIAP3,HAP1,SLC16A4,CDO1,HAPLN1,DGKG,MFAP3L,ECM2,EDNRA,IRAK4,KAT8,ALDH1L1,PCDH17,GPD2,HLF,SHISAL1,MATN3,NF1,NFYA,NPTX1,CLDN11,TREM2,PALM,PCDH9,CDK18,PDE4B,PFKFB2,PFKFB4,PLCB2,PTN,FAM184A,ENOX1,RGS4,RNASE1,EMID1,AP1AR,SAFB,RASA3,SLC2A5,PKNOX2,ATP10B,FLRT2,SPHK2,REEP1" Drug 3542_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-09 4.58E-05 5.45E-07 6.14E-06 53 196 "FZD9,PRX,DNAH17,ATP6V0A1,CFLAR,ST3GAL5,ARHGEF1,COL4A5,CSF1R,DOCK4,DTNA,DUSP9,EDNRA,PLXNC1,MTSS1L,FGFR1,IQCG,PDLIM5,GALC,MALT1,GNAO1,ATXN2L,ICA1,MBD1,MID1,AFDN,MYO7A,NPY,PCBP3,NTRK2,LRP12,SAMD9,VPS13C,ZSCAN2,TCP11L1,RPS6KA2,SALL1,SYBU,SLC4A3,EPN2,FAM214B,FAIM2,THSD1,PLCB1,ASTN2,PCDHA5,TK2,R3HDM1,TRIO,TRPM2,CLIP2,XRCC4,DNALI1" Drug 7236_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-09 4.95E-05 5.71E-07 6.44E-06 50 180 "NME5,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,CRY2,PDE4DIP,ARMCX2,JAKMIP2,TSPAN5,OPTN,FYN,CYP46A1,RAB40B,TDRKH,STON1,MAP2,MITF,MPP2,MXI1,NEK1,SERPINI1,PMP22,PKIA,GRAMD1C,PRPH,PTCH1,SH3BGR,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,CCDC88A,SMARCD3,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,SLC30A3,SLC17A7,ITM2C" Drug 3510_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-09 4.95E-05 5.71E-07 6.44E-06 50 180 "ABHD6,NME5,KIAA1324,ALCAM,APLP1,SEMA4G,MARK4,ST3GAL5,CBFA2T2,CLGN,PDE4DIP,ARMCX2,TMCC2,MBNL2,RASGRP2,FYN,ERAP1,CYP46A1,STON1,TJAP1,MITF,MPP2,ZNF862,SERPINI1,LRP12,PKIA,PRPH,PTPRH,FAM184A,NUDT11,SH3GL3,PPM1E,ASAP3,SYBU,FAM214B,ARHGEF40,CCDC88A,LIMCH1,ELOVL4,RGL1,STXBP1,TRIM2,OBSL1,HEY1,BEX4,TRIO,RUNDC3B,SSBP2,REEP1,ITM2C" Drug ctd:C009828 "2,4,5,2',5'-pentachlorobiphenyl" CTD 1.13E-09 4.97E-05 5.71E-07 6.44E-06 241 1467 "ABR,USP31,TEX22,ADGRF5,SEMA6A,SPOP,AMH,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,ASPA,CCDC74A,PTCH2,ZBTB10,ATP2B2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,PRC1,CCK,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,CHN2,PLEKHB1,NRXN3,COX4I1,NSL1,ENTPD4,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,SGSM2,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,PLXNC1,TMEM132E,PLEKHA1,ENO2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,AGAP2,ZMYND15,FOXO3,FLT1,SMC2,CAMKK2,CELF1,GAA,GALNT15,ZNF274,DISC1,SRRM4,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,MAP7D2,GNAL,PRUNE2,GPR37,CNTRL,GRIN2C,ZNF496,RNF165,GSTT2,ZBTB49,BVES,HAS2,HNF4G,IGFBPL1,MYLK2,SOWAHA,NKD1,KNDC1,DISP2,INSM1,ITPKA,KCND2,KIF5A,MAP6,ADAM22,MSR1,MYCN,MYT1,NEFH,NELL2,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,KCTD15,FXYD1,NECAB2,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRN2,TUG1,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,SMPD3,PPM1E,ST6GAL1,SLC8A1,ARFGAP1,OGDHL,RCOR3,FAIM2,FNBP1,SOX11,NMNAT2,TEX2,ARHGAP26,NKAIN2,ADHFE1,NECAB1,SYNE2,SYP,ANKRD12,MCF2L,PDLIM2,SATB2,ZEB1,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,MTMR14,TIMP4,RELL2,ASXL3,TLR4,DOK6,TTC3,CLHC1,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,RGS7BP,FAM13C,ACTR3B,ST8SIA2,SPATA13,JPH3" Drug 4436_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.23E-09 5.39E-05 6.00E-07 6.76E-06 49 175 "ABHD6,APAF1,CDC14B,ARNTL,ST3GAL5,HAP1,USP2,CHN2,ABCG1,LRIG1,PDE4DIP,ERC2,CTH,JAKMIP2,PLPPR4,EDN1,FRY,AASS,RGS17,PTK2B,TAOK3,BAIAP2,FYB1,FYN,STON1,TPPP,ITGA7,KCNH2,LIFR,MAP2,MAPT,PCDH9,SERPINI1,PTCH1,ENOX1,RGS4,RPS6KA2,SH3GL3,KDM4B,FNBP1,THSD1,ELOVL4,CEP68,RGL1,SYT1,KIAA0930,CDK20,CHST5,SSBP2" Drug 2268_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-09 5.39E-05 6.00E-07 6.76E-06 49 175 "NME5,ALCAM,MARK4,BMP7,ST3GAL5,GYG2,USP2,CLGN,PDE4DIP,ARMCX2,OPTN,RASGRP2,HPCAL4,FYN,CYP46A1,STON1,GPR37,PCLO,MAP2,MITF,PCBP3,TMOD2,SERPINI1,PKIA,PRPH,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,ARHGEF40,PEG10,ELOVL4,RGL1,STXBP1,WSCD1,DMXL2,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C,AP3B2" Drug 6671_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.27E-09 5.56E-05 6.00E-07 6.76E-06 51 186 "RALGAPA1,APAF1,ADGRB2,ST3GAL5,CA12,HAP1,USP2,CHN2,ABCG1,VCAN,PDE4DIP,CNTNAP2,CTH,JAKMIP2,PLPPR4,EDN1,RGS17,ETV1,PDLIM5,FYN,NEU3,PCDH17,FERMT2,GSN,GUCY1B1,FAM69A,ITGA7,KCNN2,LIFR,MAP2,KITLG,ADAM22,TAGLN3,SERPINI1,RETREG1,PRPH,PID1,ENOX1,RGS4,FBXW7,SH3GL3,ARHGAP26,ELOVL4,RGL1,SYT1,COBL,R3HDM1,TNS1,RUNDC3B,SSBP2,SLC17A7" Drug 5563_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.27E-09 5.58E-05 6.00E-07 6.76E-06 53 197 "ADD2,C1QTNF1,FAM135A,TRMT9B,BIN1,DNAH17,ATP2A2,CACNA1I,LDLRAD4,HAP1,CACNA2D2,EPS15L1,MYRIP,CNTNAP2,EDNRA,ST3GAL6,FGF1,FGFR3,GLYR1,GRM8,KIT,KPNA5,AFDN,TAGLN3,LYRM9,MYO7A,NF1,NNAT,NTRK2,NTRK3,PDE1C,NLE1,LRP12,PTH1R,ZNF493,ZMAT4,SEMA6D,CPEB3,ST8SIA1,SLC11A1,SNAP25,SNCA,ZNF415,HECW1,ZNF423,CDK19,SPART,ATP10B,SAMSN1,TRPM2,UBE3A,VIPR2,WIPF1" Drug 2667_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.27E-09 5.58E-05 6.00E-07 6.76E-06 53 197 "MTUS1,ALK,BEGAIN,PPP4R4,DNAH17,NRP2,BMP7,MTMR3,RUNX1T1,SCARB1,RAB33A,STOML1,RAB26,DCAF4,DGKG,DBT,MAMLD1,HIPK3,MBNL2,ING4,RASGRP2,ZNF549,F5,FHL1,PDLIM5,GALC,INPP5K,ADAM28,GNAO1,LILRA2,LSS,MEF2C,AFDN,NF1,NINJ2,PDE1C,NLE1,PLEC,PTPRN2,TCP11L1,SLC11A1,SLC14A1,SNAP25,PEG10,ST5,DNMBP,TBCEL,CHST5,ZKSCAN5,SH3GLB2,PRDM10,KCNAB1,PHTF2" Drug 6583_DN STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.27E-09 5.58E-05 6.00E-07 6.76E-06 53 197 "APLP1,ADGRB2,CFLAR,WASF1,FOXN3,CNTN1,ARHGEF10,DCAF8,KLHL3,PHF20L1,SEMA4D,TRMO,ATP2C1,FYN,DENND2A,GAD1,SYT17,GHR,GNG4,CACFD1,HNMT,IFI16,IL6R,NDP,CDK18,CCSER2,PTCH1,PTPRN2,SH3TC2,FAT4,MSANTD2,MAPK12,SBF1,ZNF821,ASAP3,FHOD3,SLC4A3,PEX26,ARHGEF40,KBTBD4,THSD1,IQCE,TRIM2,SZT2,THRA,TIAM1,TK2,TPM2,LMF1,XRCC4,SPHK2,EPM2A,ACTR3B" Drug 1634_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-09 6.17E-05 6.34E-07 7.15E-06 52 192 "ASPHD1,ABHD6,NDRG2,SRPX,APAF1,APC,ST3GAL5,GYG2,RAB29,CLGN,CACNA2D2,ABCG1,RASSF2,DBN1,ARMCX2,LYPD1,ANKMY1,EXTL2,REEP2,ARMCX1,FYN,TDRKH,GPR37,RASSF8,MPP2,MXI1,NPTX1,PALM,PDE4A,RETREG1,CNNM2,PTCH1,RNASEL,SBF1,SEC14L1,SH3GL3,ASAP3,FNDC3A,SLC2A5,ARHGEF40,SLC22A4,SNCA,STX1A,STXBP1,PLCB1,MTCL1,TRIM2,VGF,NDRG4,REEP1,SLC30A3,PCBP4" Drug 4442_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-09 6.17E-05 6.34E-07 7.15E-06 52 192 "BEGAIN,KIF1A,KSR1,KALRN,HAP1,CAMK2B,CAMK2G,CBS,CACNA2D2,WHRN,CABP1,CRY2,OSBPL3,CTH,GIT2,SV2B,EDN1,CELSR3,ST3GAL6,OLFM1,HPCAL4,GFER,PCDH17,GLYR1,SYNPO,KCNH2,LIFR,SHC3,MMP16,NPY,OXTR,PDE4B,PNMA3,POU6F1,CEP41,PTCH1,PTN,ACSS3,RET,RGS4,RNASEL,TCP11L1,HSPA4L,HKDC1,NLGN1,ZNF334,PDZD2,CRTC1,CHST5,TRO,OSBP2,REEP1" Drug 5206_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-09 6.17E-05 6.34E-07 7.15E-06 52 192 "NME5,SRPX,APC,APLP1,PPFIA3,MARK4,BMP7,ST3GAL5,GYG2,RAB29,HAP1,ARHGEF1,SYNGR3,CLGN,LHX2,SULT4A1,ABCG1,FAM169A,DBN1,ARMCX2,ENO2,REEP2,ZNF589,FGF12,FYN,GAD1,RUNDC3A,STON1,GRB10,GSN,KCNH2,KCNN2,MPP2,ADAM22,PCDH8,TMOD2,PTCH1,C1orf54,ZNF821,ASAP3,FAM214B,ARHGEF40,NMNAT2,ELOVL4,WSCD1,BEX4,PARD3,UCHL1,VLDLR,LAT2,NDRG4,MAP3K12" Drug 7320_UP Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "KCNAB2,APBB2,GAS7,ALDH7A1,MYRF,WHRN,HAPLN1,ABCG1,CNTNAP2,HDAC9,SUGP2,MTSS1L,TBC1D16,FGF1,EFCAB2,FYB1,SYT17,STON1,SPACA9,IGF1,SCIN,MIA2,SCAMP5,MYH3,ZNF862,PALM,SLC25A23,PPM1B,MAPK7,APTX,PTN,TMEM231,TCP11L1,SAFB,SH3BP2,AMBRA1,ST6GAL1,SLC14A1,ZNF415,SPART,CEP68,JMJD6,TACR1,EXOC7,CBX5,CABIN1,TNS1,TRPM2,WIPF1,WNT7A,XRCC4,SEMA3B,KCNAB1" Drug 6889_DN AG-012559 [369370-06-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "LTBP4,BIN1,CDC42BPA,APBB2,FAM131A,PPP4R4,ALDH7A1,C5,CFAP410,HAP1,CAMK2G,USP2,SOCS6,PLEKHB1,TAOK2,STOML1,SULT4A1,CSF1R,FAM169A,GPRASP1,DCAF8,MFAP3L,DTNA,ING4,ERCC2,DENND4A,MALT1,ATXN2L,HNMT,INPP5B,JAK2,IPO5,MIA2,NF1,SLC11A2,PCDH9,RETREG1,STRN3,SUPT20H,PPP4R3A,MAPKBP1,RBM34,KDM4B,DOP1A,SS18,ARC,ASTN2,ANKRD12,EXOC7,KIAA0930,TNS2,GDPD5,SEMA3B" Drug 6827_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "RALGAPA1,AK2,BCAS1,SCAPER,CAMK2G,SYNGR3,FOXN3,PLEKHB1,RAB28,AKAP7,NCOR1,ABCG1,FAM169A,RIMS2,RUBCN,JAKMIP2,MED12,DTNA,CELSR3,EIF5,FGFR1,SMC2,INPP5K,TXNL4A,COPS8,GLYR1,POLL,GRB10,RNFT2,ATXN2L,KCNH2,KIF2A,SETD4,PLEC,PPP5C,TMEM104,ZSCAN32,BTBD7,COA1,SNCA,DOP1A,SPTAN1,ZBTB43,POGZ,COBL,IQCE,TK2,PARD3,VAV1,VGF,REEP1,EVI5,HPS4" Drug 5862_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "APC,ATP2A2,ST3GAL5,CAMK2B,RUNX1T1,RAB26,PCYT1B,ABCG1,RIPOR2,SPOCK2,HSD17B14,MTSS1L,REEP2,ZNF589,FGF1,ANKFY1,SEPT9,GPD2,CNTRL,IGF1,TJAP1,ITGA7,KCNB1,LIFR,MATN3,CNOT4,RETREG1,LRRN3,CEP41,PTPRD,TMEM231,ACSS3,RAD51D,C1orf54,RGS3,RGS4,RGS12,ZNF821,ZFP30,SH3BP2,NLGN1,PKNOX2,SLC11A1,TSNAXIP1,SP2,ARHGAP26,SPTB,PCDHGB6,TK2,PIK3R5,TPM1,HPS4,KCNAB1" Drug 5916_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "ASPHD1,ADORA2A,ADRB2,NME5,ALK,CDC42BPA,APAF1,APC,GAS7,SLC4A4,CD86,RAB33A,STOML1,CSF1,FAM169A,ARMCX2,MFAP3L,PARD6A,DTNA,SRPK3,DLC1,FYN,SRCAP,PCLO,SPACA9,IL6R,KCNJ5,KHK,MAP4,MID1,MMP16,MYO7A,ZNF862,NF1,PCBP3,PDE1C,WDR25,RGS3,TCP11L1,RPS6KA2,SLC4A3,SLC2A5,ARHGEF40,SLC11A1,COA1,LIMCH1,RBM34,DICER1,CHST8,TMPO,TNS1,CA14,XRCC4" Drug 4236_UP Gabazine [105538-73-6]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "NME5,PKP4,MARCH3,BMP7,SYNJ1,LDLRAD4,HAP1,RUNX1T1,CHRNA4,ARHGAP22,QKI,HOMER3,HAPLN1,PDE4DIP,CNTNAP2,MAML1,DAPK3,EXOG,COQ7,ZNF391,ETV1,PIPOX,PTK2B,FGFR1,DCTN2,DLL3,RAB30,STON1,GRIK5,CACFD1,ATXN2L,MAN2A2,TM6SF1,MMP16,LYRM9,NPTX1,NTRK3,PDE4A,PDPK1,PLXNB1,PPP5C,MAPK10,C1orf54,GAL3ST4,PKNOX2,ZNF334,CXXC4,ZC3H13,ADGRL3,AP4E1,ICAM5,LAT2,DPF3" Drug 3700_DN Merbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "ADD2,AGT,APBB2,APOC1,SEMA4G,SLC4A4,MYRF,CAST,ARHGAP33,CACNA2D2,TAOK2,FAM189A2,HOMER3,CNTN1,NCOR2,VCAN,SLITRK5,DTNA,FAM13A,FGF1,FGFR1,SRCAP,STON1,ICA1,SHISAL1,KCNB1,KCNJ5,KHK,MIA2,ADAM22,MYO7A,NF1,NFYA,NPR2,CLDN11,CEP41,PTN,ACSS3,ENOX1,KCTD17,TCP11L1,SCN8A,DZIP1,PKNOX2,KIF13A,SP4,ARHGAP26,SPTB,THSD1,RPGRIP1L,BHLHB9,RPRM,UBE3B" Drug 4839_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "BIN1,APBB2,PDE8B,ADAM23,BAIAP3,RHBDL1,CDH2,CLGN,FOXN3,B4GALT6,ENTPD4,SNCAIP,CTH,DCAF4,CYBB,RASSF2,TBC1D5,TMCC2,RCAN1,VPS26C,AGAP2,DCTN2,GPER1,PCLO,SPACA9,ATXN2L,TJAP1,JAK2,KCNH2,KHK,ADAM22,MSR1,MYT1,PLCD1,MBOAT7,MAPK7,SALL1,ST6GAL1,CNKSR2,FAIM2,TSNAXIP1,ZSWIM8,HECW1,CLSTN2,SS18,SZT2,PCDHGA10,PCDHA6,CDK20,XRCC4,NT5M,ITM2C,HRASLS" Drug 7227_UP Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "KIAA1324,SYT13,AMPD3,BIN1,APAF1,ARHGDIG,AZGP1,NRP2,CFLAR,SCAPER,CA4,USP2,ARHGEF1,PLEKHB1,STOML1,C3orf18,BAIAP2,ANKFY1,OGA,ERAP1,SRCAP,GNAL,LPAR4,GPR37,SPACA9,GRIK5,GRM8,MAP4,MGAT3,AFDN,MYO7A,ZNF862,NF1,NFYA,CNOT4,LRP12,MINDY2,PPP5C,ELOVL2,PTPRO,KHDRBS2,GSTCD,KCNIP1,SCN2B,ZFP30,FAM102A,SNCA,ZNF415,PHLDB1,TBL1X,WIPF1,ST7,JPH3" Drug 3554_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "ASPHD1,AMPD2,OGT,APBB2,CDC14B,MARK4,C5,RAB29,CA12,AP4M1,VAX2,SULT4A1,NCOR1,PDE4DIP,MAML1,JAKMIP2,DMPK,FCF1,ING4,ANKMY1,TPK1,GNG4,GPR37,GRB10,KCNF1,LIG4,MAP4,MIA2,LYRM9,PCDH9,PPP3CC,ELOVL2,GSTCD,ZNF821,FBXO11,WDR47,SLC6A8,CDK5RAP2,LIMCH1,RBM34,SP2,UHRF1BP1L,CEP68,DIP2A,EXOC7,DNMBP,SMG6,TRIM2,HIRA,VGF,LMF1,ZBTB14,AAAS" Drug 4258_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-09 6.79E-05 6.34E-07 7.15E-06 53 198 "MTUS1,PDE8B,ST3GAL5,CBFA2T2,RAB26,WHRN,CREM,PDE4DIP,CNTNAP2,PPP6R2,ARHGAP24,TBC1D5,KIAA0753,KLHL3,DYNC1I1,RGS17,COQ7,ETV1,ST3GAL6,ZNF589,TRMO,POLL,PRRC2B,BACH2,HNMT,SHISAL1,FAM69A,ITPKB,MX1,NDP,CNOT4,CLDN11,PIK3R1,RETREG1,PLCD1,PPARA,GRAMD1C,PRPH,PTPRN2,TMEM231,ENOX1,RXRA,SUPT20H,ZFP30,SAMSN1,IQCE,ZNF34,SMUG1,HIRA,WIPF1,ZNF74,FZD3,PHTF2" Drug 7324_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.87E-09 8.19E-05 7.19E-07 8.10E-06 49 177 "ABHD6,NME5,MARK4,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,ARMCX2,TSPAN5,OPTN,MBNL2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,PADI2,MITF,MPP2,MXI1,SERPINI1,PKIA,PRPH,PTCH1,SH3BGR,SH3GL3,PPM1E,SYBU,WDR47,FAM214B,PKNOX2,LIMCH1,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 5604_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.88E-09 8.24E-05 7.19E-07 8.10E-06 53 199 "NDRG2,FAM135A,APAF1,APOC1,ARHGDIG,SCAPER,GYG2,CFAP410,CA4,USP2,WHRN,COL9A3,NCOR2,AATK,PHF14,RASSF2,BRINP1,EDNRA,EIF4G2,RASGRP2,ABCA8,FGF1,FHL1,CAMKK2,GAD1,DISC1,SEPT9,ALDH1L1,GLYR1,PRUNE2,PCLO,SHISAL1,NNAT,ENPP2,PURG,LRP12,POU6F1,MAPK10,DCHS2,PTCH1,MRAS,SLC9A5,ZNF415,PDZRN3,TSNAXIP1,HECW1,SPTB,PLCB1,ANKRD12,WSCD1,TRIM2,TRPM2,SLC17A7" Drug 5772_UP Oxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.88E-09 8.24E-05 7.19E-07 8.10E-06 53 199 "RALGAPA1,SYN3,ADORA2A,NME5,BEGAIN,EPB41L5,ADGRB3,RGS9,CALB2,MTMR7,CD86,PLAA,HOMER3,ABCG1,RIMS2,DGKG,ECM2,FRY,ING4,NCALD,APC2,EZH1,FGF1,FGF12,OGA,GNAO1,NXPH3,ATXN2L,KIFC3,LMO2,MAN2A2,MSR1,MYCN,NRCAM,OPRL1,PTCH1,PTPRB,RASA3,PPM1E,FRMPD1,HKDC1,DZIP1,SLC8A1,SLC11A1,SLC14A1,KIF13A,SP4,SPP1,SPTAN1,DICER1,SLC44A1,TLR4,RPRM" Drug 2697_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.88E-09 8.24E-05 7.19E-07 8.10E-06 53 199 "MTUS1,SPARCL1,SEMA6A,ANK2,ZSCAN18,ATP2B2,AZGP1,RGS11,BMP7,HIP1R,ENTPD2,CHN2,CABP1,AKAP5,NRG2,ARHGEF10,RCAN1,BAIAP2,DLL3,SIGLEC8,ADAM28,GPR75,LILRA2,SPACA9,MN1,PDE4A,PRKAR1B,MAPK10,PRPH,WDR25,ACSM5,CCDC40,RGS4,NEK11,EMID1,ZFP2,SGK1,CNKSR2,CCDC88A,SPTAN1,PHLDB1,ARC,SYP,RPGRIP1L,PHF24,HIF3A,TIAM1,TNS1,CHST5,TRO,FAM155A,EVI5,PHTF2" Drug 6618_UP Protoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.88E-09 8.24E-05 7.19E-07 8.10E-06 53 199 "ADORA1,C1QTNF3,GAS7,SYNJ1,HAP1,CBS,CRLF1,FOXN3,RCHY1,PLPPR4,SPOCK3,DTNA,EGFR,ING4,APC2,ETV1,DLC1,FGF1,FGF12,FGFR1,FLT1,DCTN2,ALDH1L1,GSN,GSTM5,ATXN2L,ICA1,SCIN,MEF2C,AFDN,PALM,ENPP2,PGAM2,PRPH,VPS13C,ZSCAN2,C1orf54,RGS4,SUPT20H,ASAP3,PEX26,PHLDB1,TACR1,TAL1,CDK20,RUNDC3B,VGF,LAT2,ZNF24,ZNF74,KCNAB1,EPM2A,NLRP3" Drug 3580_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.88E-09 8.24E-05 7.19E-07 8.10E-06 53 199 "ASIC1,KCNAB2,APOC1,CHRD,ATP1A3,KSR1,SYNJ2,SCAPER,ARHGEF1,CRLF1,CHN2,HOMER3,CNTFR,COL9A3,RCHY1,CNTNAP2,RCAN1,KAT8,AGAP2,FYN,TMEM8B,GPR75,GPER1,ADAMTS13,TJAP1,KCNB1,KCNN1,SMAD1,MGAT3,AFDN,NF1,NOVA2,OPRL1,PALM,MBOAT7,POLG,MINDY2,PRODH,RELN,SAMD9,ELOVL2,ZNF493,RGS12,SLC9A5,OGDHL,KDM4B,CDK19,SZT2,SYNE1,SLC44A1,TUBB1,CLIP2,GDPD5" Drug ctd:C006703 benzo(b)fluoranthene CTD 1.88E-09 8.25E-05 7.19E-07 8.10E-06 253 1564 "NCKAP5,ADCY5,NME5,SORCS2,ADGRF5,SEMA6A,ARHGAP20,BIN1,SEMA7A,LCORL,CPNE5,LGR5,PPP4R4,ARNTL,ASGR1,ASPA,MARK4,NUMB,ATP2A2,ADAM15,BARD1,BCHE,RGS9,GPR146,C5,CA8,THSD7A,HAP1,CAMK2G,PRC1,USP2,CD38,ENTPD2,MS4A7,ARHGAP22,CLTB,ABCG2,MAP4K4,HOMER3,AKAP7,ABI3BP,NSL1,NECTIN3,CLOCK,CREM,ANKRD44,GDA,AATK,CSF1,CSF2RA,OSBPL3,RASGEF1C,CTH,GREB1,DCAF4,MYADM,KCTD8,BRINP1,DBI,ELMSAN1,GSDME,SLC29A4,DYNC1I1,NR1D2,ARRDC4,ABCC5,EDIL3,EDNRB,KLHL5,TMTC1,FAM13A,EGFR,KMT5B,RASA4,AASS,SRPK3,EPB41,ADGRV1,REEP2,ABCA8,FAM198B,TUBA1B,PTK2B,FGF1,FGFR3,POLK,HPCAL4,ZMYND15,SMC2,APOPT1,TRIM16,TPK1,CGREF1,NSG1,STAU2,AP4B1,OGA,SDCBP2,GAA,GALNT15,SRRM4,CPLX2,GCK,GPR162,PCDH17,LYVE1,SPIN1,TOX3,AIFM3,HTATSF1,ADGRA3,GPD1,CCDC184,STON1,STMN2,GRB10,DIDO1,PLCD4,SERP2,GRIN2C,BVES,FAM107A,SLC2A6,ATOH8,NXPH3,HLF,HMGCR,CFAP126,CPT1C,CELF5,ICA1,IFI16,IGF1,NKD1,DISP2,ITGA7,KCNB1,KIT,STMN1,LIG4,LSS,ZFYVE27,MAT2A,TM6SF1,MEST,KITLG,PPM1L,BLOC1S2,MSR1,THYN1,LAYN,NEXMIF,P2RY13,NNAT,PCBP3,NRCAM,P2RX7,TREM2,PDE4A,TMOD2,CYTL1,PFKFB3,PGAM2,ABCB1,PLCD1,PLEC,PLIN1,PLXNB1,PMP22,PPP2R2C,MAPK10,SLC26A11,LAMA1,GDPD2,MTMR10,PTPRB,PTPRG,TTC13,TUG1,TMEM255A,SUSD4,FIGN,RGS12,LGI2,ROBO2,GLDN,EMID1,MEG3,HUNK,NCBP3,SCN7A,PEAR1,SHC4,HKDC1,FHOD3,R3HDM2,DZIP1,EPN2,FAM214B,SLC8A1,ARHGEF40,SLC12A4,ARFGAP1,MAST1,FAM126B,TRERF1,SOX11,SPP1,UNC5B,ZNF423,CLSTN2,THSD1,SEPT8,SULF2,SEPT3,STXBP1,SYNE2,PLCB1,SYN2,SYT1,COBL,ANKRD12,TAF6,TCF12,SZT2,PCDHGA9,PCDHB10,NSD1,PCDHAC2,GPRIN3,SLC35G2,ZMAT3,CDH22,THRA,TIAM1,HEY1,TNS1,RASD2,ZNF346,CA14,TUBB2A,UCHL1,RBFOX3,REEP1,PROCA1,GDPD5,TMEM178A,HPS4,RGS7BP,FAM13C,TTC7A,AAAS,CPNE4" Drug 3046_UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.90E-09 8.33E-05 7.19E-07 8.10E-06 51 188 "SYT13,ANK2,DNAH17,AZGP1,MPDZ,CACNA1G,CD86,CBFA2T2,CD38,SOCS6,CHN2,COL9A3,NRG2,CREM,AATK,ARHGEF10,SUSD5,SIPA1L1,VCAN,PPP1R16B,DOCK4,HEYL,ING4,BAIAP2,TRAF3IP2,GALC,SIGLEC8,RUNDC3A,PCLO,RASSF8,HNMT,MEF2C,MMP16,NDP,NTRK3,SMOX,MAPK7,BCAS3,BEND5,RGS12,NUDT11,SCN8A,CNKSR2,ZC3H13,CDK19,PLCB1,TACR1,RUNDC3B,TRPS1,FLRT2,LMF1" Drug ctd:C118580 octylmethoxycinnamate CTD 1.91E-09 8.37E-05 7.19E-07 8.10E-06 42 140 "ACTN1,UNC5A,CASK,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CAMK2B,CACNA2D2,CHRDL1,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,FGFR1,FYN,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,NXPH3,IGF1,NF1,NRCAM,NTRK2,NTRK3,OGG1,CNTN3,RELN,ROBO1,STX1B,HES6,NLGN1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug ctd:D004390 Chlorpyrifos CTD 1.92E-09 8.41E-05 7.19E-07 8.10E-06 171 968 "ASIC1,ACHE,AXIN2,FZD9,ADRA1D,ADRB2,AGT,ALCAM,ALK,AMPD3,LRFN1,CDC42BPA,SEMA7A,APAF1,APOC1,SEMA4G,PPP4R4,TMEFF1,ARRB1,ALDH7A1,BCHE,AP1M1,CAMK2A,CAMK2B,CCK,USP2,CD86,SCARB1,DLGAP2,FOXN3,CHGB,SLIT2,CLCN3,ABCG2,ABI3BP,RBM39,CRHBP,GDA,CLIP3,CST3,DZIP3,TCAF1,MATR3,DNAL1,SPATA2,FAM107B,GRIN3A,DTNB,DNM1L,EDNRB,RASGRP1,FRY,EGFR,EIF5,TUBA1B,TUBB3,FKTN,FGF1,FGF11,PRKAG2,NOP56,CINP,CGREF1,GFRA2,GGT7,TXNL4A,PCLO,GRB10,GRIA2,GRIK4,GRIK5,GRM2,GSTM5,GSTT2,HP,NEGR1,IGF1,KIT,L1CAM,MAP2,EFHB,MEF2C,MEIS2,MX1,MYCN,MYO5A,MYO7A,FXYD7,NEFM,NEFH,NFE2L2,NFIX,CNOT4,NPY,NPTX2,NRCAM,NTRK2,NTRK3,IGSF11,OPRL1,OXTR,PDE1C,GPR85,TMOD2,PFKFB3,PFKFB4,ABCB1,PCDH18,ING3,SH3KBP1,MINDY2,LRRN3,PPP3CA,PRKAB2,RASGEF1B,PRKCB,MAPK3,HYDIN,RELN,PTK2,KHDRBS2,RET,ROBO2,BAALC,FAM192A,S100B,DGLUCY,SCP2,SGK1,FAM81A,SLC6A8,SLC12A2,SNCA,USP33,SOX3,HECW1,MYCBP2,SST,SSTR2,ERBIN,TTBK2,ADHFE1,SULF2,ARC,SYP,TCF4,ZEB1,PCDHA6,ZNF106,AKTIP,CDH22,TK2,TLR4,LRRC8A,BEX4,ZNF346,TSN,UBC,VLDLR,RBFOX3,LAT2,ZIC1,SLC30A3,SLC38A1,CIAPIN1,SEMA3B,FZD3,RTN4,NLRP3,ZDHHC20,SENP7" Drug 3900_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 9.16E-05 7.64E-07 8.60E-06 52 194 "LTBP4,SLC2A11,SCAPER,CACNA1I,LDLRAD4,RCBTB2,CHN2,TPP1,WHRN,RCHY1,CRMP1,C3orf18,SPEG,PTK2B,DLC1,OLFM1,FGFR3,SEMA4D,FLNC,CSPG5,GAD1,INPP5K,GLYR1,GPER1,PCLO,SYNPO,TJAP1,KCNN2,KIT,MAPT,MIA2,MX1,MYO9A,ZNF862,PCBP3,RETREG1,NECAB2,MINDY2,ZNF493,ZFP2,ZNF821,ASAP3,UNC5B,ATP10B,TBCEL,SYNE1,UBE3A,VLDLR,SPHK2,PRDM10,SLC17A7,KCNAB1" Drug 3641_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 9.16E-05 7.64E-07 8.60E-06 52 194 "BIN1,GAS7,APOC1,MARK4,CA4,USP2,ARHGEF2,CHRNA4,WHRN,CRMP1,SPOCK3,HS3ST2,CDON,EDN1,HSD17B14,CDKL3,EYA1,CAMKK2,FYB1,ZNF44,GABRG2,SEPT9,GRIK5,PTPRT,KCNN1,LAMA2,ZNF862,NF1,TREM2,PCDH9,RETREG1,PLCD1,NECAB2,ELOVL2,MARCH1,ASAP3,DZIP1,SLC11A1,TSNAXIP1,NMNAT2,LMO3,ATP10B,SSTR2,ADGRL3,WSCD1,HIF3A,TK2,OSBP2,PLPPR2,VSNL1,KCNAB1,HRASLS" Drug 7347_UP Zardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 9.16E-05 7.64E-07 8.60E-06 52 194 "RALGAPA1,ASPHD1,NDRG2,AGT,AMH,MARK4,KSR1,SCAPER,GYG2,B4GALT6,HOMER3,WHRN,CREM,CSF1,CSF1R,PDE4DIP,FAM169A,GIT2,PARD6A,PHF20L1,ING4,STX2,ERCC2,EZH1,TPK1,ALDH1L1,SRCAP,MALT1,TDRKH,CNTRL,HLF,SYNPO,INPP5B,TM6SF1,MEIS1,MPP2,ADAM22,NF1,SLC11A2,MINDY2,ZMAT4,RGS12,RPS6KA2,SBF1,FBXO11,EPN2,SLC8A1,SMARCD3,WSCD1,DICER1,UCHL1,ITM2C" Drug 5523_UP Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.28E-09 9.99E-05 8.26E-07 9.30E-06 53 200 "RALGAPA1,KIAA1324,AK2,SYT13,BEGAIN,APBA2,KCNAB2,CDK10,DNAH17,CALB1,RUNX1T1,CBFA2T2,FOXN3,STOML1,CNTN1,AKAP7,SIPA1L1,PHF14,SNPH,DBN1,EDNRB,MTSS1L,NCALD,CDKL3,KAT8,OLFM1,FHL1,FYB1,HPGDS,POLL,GNG4,KCNH2,IPO5,LAMA2,MAN2A2,MEF2C,NDP,PDE4B,GPR85,PTX3,ZDHHC14,TCP11L1,PKNOX2,ELMO2,HECW1,STX1A,SYT5,MCF2L,TBCEL,PCDHGA10,CABIN1,SLC17A7,FAM13C" Drug 6454_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.30E-09 1.01E-04 8.26E-07 9.30E-06 49 178 "NME5,APLP1,ST3GAL5,SGCE,CACNA1I,RAB29,CLGN,WHRN,COL9A3,AKAP12,PDE4DIP,DOCK4,ARMCX2,OPTN,FAM13A,RASGRP2,STX2,SPEG,FYN,CYP46A1,RAB40B,STON1,ITGA7,MPP2,MXI1,SERPINI1,SLC25A23,PRPH,PTCH1,RPS6KA2,SH3GL3,PPM1E,WDR47,ARHGEF40,LIMCH1,ELOVL4,RGL1,STXBP1,WSCD1,TRIM2,HEY1,BEX4,TNS1,RUNDC3B,NDRG4,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 2152_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.54E-09 1.11E-04 8.98E-07 1.01E-05 52 195 "C3orf14,FGD2,DDO,APOC1,CDC14B,RASL11B,SLC4A4,PROM1,CA12,MAGI1,B4GALT6,ABCG2,FAM149A,ARHGEF10,RIMS2,ARHGAP24,SEMA3D,C3orf18,ERBB2,ETV1,DLC1,FGFR1,ZNF44,GALC,ALDH1L1,PCDH17,GNAL,STON1,STMN2,KCNH2,MAP4,NPR2,NTRK2,MTRF1L,ACSM5,SUSD4,ENOX1,ZFHX4,NEK11,SEMA6D,STUM,SLC14A1,KIF13A,ZHX3,SSTR2,DIP2A,SYNE1,TK2,RUNDC3B,FAM155A,SLC30A3,FZD3" Drug 3201_DN Lidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.54E-09 1.11E-04 8.98E-07 1.01E-05 52 195 "SEMA6A,CDC42BPA,SLC4A4,ATP2A2,ATP6V0A1,KIF1A,CFAP410,USP2,CACNA2D2,PLEKHB1,TAOK2,QKI,NECTIN3,SH2B1,ARHGEF4,PPP6R2,CYBB,SPOCK3,ERCC2,DENND4A,APC2,FGFR1,ZNF44,GABRG2,ERAP1,COPS8,LPAR4,GRB10,RASSF8,IL6R,INPP5B,KCNH2,MATK,GIT1,NNAT,RETREG1,POLG,RELN,PTPRO,ZSCAN2,RGS12,CARF,NEK11,EMID1,FNDC3A,ANKRD6,NSD1,THRA,VIPR2,HPS4,UBE3B,SMIM8" Drug 4184_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.82E-09 1.24E-04 9.81E-07 1.11E-05 49 179 "ADRB2,MTUS1,APAF1,EPB41L5,SHROOM2,CDC14B,ARNTL,MARCH3,ST3GAL5,SYNGR3,PREPL,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,PTK2B,TAOK3,BAIAP2,NBEA,FYN,PCDH17,STON1,GUCY1B1,BACH2,FAM69A,KCNJ5,LIFR,TAGLN3,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,PTN,ENOX1,RGS4,RPS6KA2,RPS20,SH3GL3,DOP1A,THSD1,ELOVL4,CEP68,RGL1,SYT1,COBL,TNS1,SLC30A3" Drug 2700_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.82E-09 1.24E-04 9.81E-07 1.11E-05 51 190 "C3orf14,AMH,BIN1,APBB2,DNAH17,RGS11,CACNA1G,CACNB4,HIP1R,USP2,LHX2,RAB26,FAM149A,COL9A3,NRG2,PDE4DIP,DZIP3,EGFR,MBNL2,AASS,GABRA3,SIGLEC8,GNAO1,GPD1,STON1,GUCY1B1,RASSF8,IFI16,KCNJ5,PACRG,MAPT,RGS4,SUGCT,CNKSR2,KANSL3,ZNF415,ATP10B,RGL1,SYT5,TRIM2,FAM189A1,GPR161,TIAM1,TK2,TPM1,AMACR,TRO,OSBP2,MAP3K12,DNALI1,EVI5" Drug CID000004873 K-Cl Stitch 2.84E-09 1.25E-04 9.81E-07 1.11E-05 112 567 "KCNH8,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,AMPD2,AMPD3,MYH7B,AQP6,MARK4,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,KSR1,CA8,CACNA1A,CACNA1B,CACNA2D1,CALB1,CALM1,CAMK2B,CCK,KRIT1,ENTPD2,CHGB,MYL6B,SULT4A1,CREM,CRYM,CS,CSNK1E,CSNK1G3,EARS2,GSDME,DMPK,SLC12A6,DTNB,AASDH,EDN1,EDN3,EDNRA,EDNRB,PTK2B,POLK,ATP2C1,GCK,MSTN,SESN1,KCNMB4,GRIK4,GRM2,GSN,GUCY1B1,HMGCR,HSF2,IDH3A,MYLK2,KCNJ5,KCNK3,MARK3,AQP11,AFDN,MYH3,MYO5A,MYO6,MYO9A,NBL1,NPY,NPR2,KSR2,P2RY1,PKM,POLG,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RELN,REV3L,RNASE1,RYR3,SAFB,MAPK12,ARX,MYO18A,SLC12A2,SLC12A4,SNAP25,PEG10,SST,SYN2,TACR1,SMG6,ZEB1,TIMP4,ACTR6,TPM1,NPL,TPM2,WIPF1,SPHK2,PLD4,FZD3" Drug 4419_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.08E-09 1.35E-04 1.02E-06 1.15E-05 52 196 "SYN3,ASIC1,ADORA1,LTBP4,BEGAIN,AMH,KCNAB2,CDC14B,ARHGDIG,BTK,CACNA2D1,SLC16A4,CD86,CDO1,STOML1,SULT4A1,PCYT1B,VCAN,CTH,BRINP1,DBT,MBNL2,C3orf18,OLFM1,LYVE1,GPER1,SPACA9,JAK2,KCNJ5,KIFC3,MN1,MX1,MYT1,NPR2,PFKFB2,PRKCB,PTPRB,ZNF493,RGS12,SBF1,ZNF821,SLC2A5,KANSL3,SLC11A1,COA1,SMARCD3,ATP10B,TACR1,HIF3A,UCHL1,WIPF1,ITM2C" Drug 5568_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.08E-09 1.35E-04 1.02E-06 1.15E-05 52 196 "ADD2,ADRA1B,AGT,AMPD3,BIN1,APBA2,APC,DNAH17,RASL11B,SYNJ1,CAMK2B,CREM,GREB1,DOCK4,DMPK,EGR3,OLFM1,DCTN2,CAMKK2,FYN,CPLX2,ALDH1L1,RUNDC3A,GLYR1,GRM8,JAK2,KCNQ3,TM6SF1,MMP16,MYCN,NOVA1,CDK18,PDE4A,PLCD1,VPS13C,PTH1R,ELOVL2,C1orf54,SGK1,SH3GL3,SYBU,SLC9A5,SLC11A1,SNCA,SAMSN1,TAL1,AP4E1,R3HDM1,UBE3A,WIPF1,LAT2,PHTF2" Drug 5115_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.08E-09 1.35E-04 1.02E-06 1.15E-05 52 196 "ALK,AMPD3,APC,GAS7,APLP1,BCL7A,LDLRAD4,CAST,RUNX1T1,FOXN3,STOML1,VAX2,ABCG2,HOMER3,WHRN,EDNRA,HIPK3,SEMA3D,C3orf18,APC2,F5,GAD1,SRCAP,LYVE1,GUCY1B1,ICA1,TJAP1,ITGA7,KCNQ3,MMP16,ADAM22,RETREG1,PLCD1,ZNF426,MINDY2,PTPRH,ZSCAN2,TMEM231,RGS12,NEK11,RPS6KA2,SEC14L1,FAM102A,ST6GAL1,CNKSR2,TMCC1,ARHGAP26,ZBTB43,ARC,SZT2,ZFPM2,SPHK2" Drug 3261_UP Lysergol [602-85-7]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.08E-09 1.35E-04 1.02E-06 1.15E-05 52 196 "ABHD6,C1QTNF3,TRMT9B,PPP4R4,RGS20,ARRB2,SLC4A4,ALDH7A1,CFLAR,CACNA1I,CFAP410,CA12,KYAT1,CNTFR,AATK,RIMS2,SEC14L5,BRINP1,MFAP3L,DMPK,HIPK3,VPS13B,F5,FGFR1,GAD1,GLYR1,GPER1,ICA1,IL12A,KCNH2,MID1,GIT1,NF1,NNAT,OGG1,RETREG1,STRN3,NECAB2,PRKACB,MAPK10,PRPH,RAD51D,GAL3ST4,ZFHX4,PREX2,TSPYL2,SPART,CAMTA2,SLC19A3,GDPD5,TIGD6,RNF146" Drug 5689_UP Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.08E-09 1.35E-04 1.02E-06 1.15E-05 52 196 "NDRG2,ADCY6,ADORA1,ADRA1B,C1QTNF3,SPARCL1,MTMR3,CACNA1I,MYRF,CALB2,SEPT7,FOXN3,STOML1,RGS6,PDE4DIP,ARHGEF4,RASSF2,DBT,SPOCK3,DPP6,DRP2,EGR3,ETV1,F5,FGFR1,FOXF2,AGAP2,FYN,KCNJ5,KCNN2,SMAD9,MEF2C,NCF2,NF1,PLXNB1,TRHDE,MINDY2,GDPD2,CCDC40,RASGRF1,TCP11L1,SLC2A5,MAST1,SNCA,TROVE2,SYP,TAL1,ADGRL3,TEK,DICER1,SPHK2,SEMA3B" Drug 5484_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.45E-09 1.51E-04 1.14E-06 1.28E-05 49 180 "NME5,APAF1,CDC14B,SEMA4G,MARK4,ST3GAL5,BAIAP3,CLGN,DOCK4,ARMCX2,JAKMIP2,FAM13A,MBNL2,RASGRP2,STX2,CDKL3,PTK2B,BAIAP2,FYN,CYP46A1,COPS8,RAB40B,STON1,MXI1,PDE4A,SERPINI1,PRPH,PTCH1,PID1,NUDT11,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,SOX15,ZBTB43,THSD1,ELOVL4,RGL1,STXBP1,KIAA0930,TRIM2,RPGRIP1L,GPR161,HEY1,RUNDC3B,EVI5,SLC17A7" Drug 4729_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "RALGAPA1,ASIC1,LTBP4,AMPD3,BIN1,APC,APOC1,ARRB2,CDH2,CDO1,CACNA2D2,CNN3,CNTN1,NECTIN3,RGS6,CNTNAP2,ARHGAP24,SPOCK2,RUSC2,DMPK,RASGRP2,DISC1,NEU3,ALDH1L1,GNAL,PCLO,KCNH2,MAPT,MATK,MATN3,LRP1B,AFDN,NF1,PLCD1,MAPK7,RELN,PTCH1,ELOVL2,ZSCAN2,RORB,SLC14A1,MYH15,SNCA,KDM4B,ZSWIM8,PEG10,ARHGAP26,OSBP2,BCL2L13,KCNK12,SLC30A3,AP3B2" Drug 2174_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "MTUS1,CDC42BPA,APC,SEMA4G,PRX,DNAH17,MPDZ,CFAP410,SYNGR3,ABCG1,AATK,VCAN,RIMS2,CDON,DTNB,MBNL2,EGR3,BAIAP2,AGAP2,CSDC2,RUNDC3A,ZNF276,GNAO1,STON1,SPACA9,GSN,AP4S1,KCND1,MAP4,MBP,MMP16,ADAM22,SAMD14,NNAT,ENPP2,PFKFB2,PLCD1,SLC25A23,MAPK7,GRAMD1C,WDR25,NKAIN1,ZMAT4,RGS4,RGS12,FRMPD1,CCDC92,LHPP,VIPR2,LMF1,XRCC4,KCNAB1" Drug 2327_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "ASPHD1,AP2A2,BIN1,CDC42BPA,APOC1,RGS20,CDK13,SLC2A11,SCAPER,GYG2,BAIAP3,SCARB1,ARHGEF2,SLIT2,RAB33A,LY86,WHRN,CRMP1,NCOR2,DZIP3,RIMS2,C3orf18,VPS26C,ACSL4,ZNF589,ADAM28,USP19,MSL3,GRIK5,TJAP1,ITPKB,MMP16,LYRM9,ZNF862,CNOT4,NPR2,CDK18,GPR85,RETREG1,SLC25A23,LRRN3,PRKAR1B,ELOVL2,ZSCAN2,FRMPD1,BTBD7,WSCD1,THRA,TK2,XRCC4,GDPD5,KCNAB1" Drug 5496_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "SYN3,APC,FAM131A,ATP2A2,ALDH7A1,AZGP1,MTMR2,HAP1,RCBTB2,FOXN3,SULT4A1,PICK1,CNTN1,BRINP1,MED12,HIPK3,PLXNC1,HSD17B14,LRRC17,RASGRP2,APC2,EZH1,FER,ANKFY1,PRELID3A,GCNT2,COPS8,KCNJ5,LSS,GIT1,LYRM9,NPR2,P2RY1,LRP12,PPARA,PTPRO,PNMA8A,ZNF821,COA1,HECW1,ZC4H2,ST5,SYT5,MCF2L,SMG6,RPGRIP1L,PHF24,PIK3R5,TRPM2,EMSY,NT5M,KCNAB1" Drug 6273_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "BRAP,AGT,APC,ARHGDIG,SLC4A4,CFLAR,ST3GAL5,SYNJ2,VAX2,QKI,ARHGEF10,PDE4DIP,GREB1,ARHGEF4,DMD,DMPK,HIPK3,MBNL2,STX2,ZNF589,PDLIM5,KHDRBS3,FYB1,SRCAP,CACFD1,MUM1,INPP5B,ITPKB,MAP4,AFDN,MPP2,NF1,CDK18,RETREG1,PLEC,PPP2R2B,GRAMD1C,ZCWPW1,KHDRBS2,GSTCD,FBXW7,RPS6KA2,PEX26,PHLDB1,ARHGEF9,RPGRIP1L,CHST5,ZKSCAN5,PLPPR2,GDPD5,HPS4,ST7" Drug 7012_DN Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.73E-09 1.63E-04 1.18E-06 1.32E-05 52 197 "ASPHD1,ADD1,APOC1,PPFIA3,CDC14B,ARRB2,CDK13,ZBTB10,MPDZ,CCNT1,TMEM184B,HOMER3,CREM,DCAF8,DAPK3,GIT2,B3GAT3,SGSM2,FEM1B,VPS26C,FGFR1,BAIAP2,MPP6,FYN,B4GALNT1,MALT1,COPS8,MSL3,GPR37,DHX35,IL6ST,KHK,MITF,NFYA,OGG1,SLC25A23,SMIM7,FSD1,SEC14L1,SUPT20H,SYBU,BTBD7,DIP2A,MCF2L,TBL1X,HIRA,UBTF,VAV1,LMF1,FTSJ1,GDPD5,VPS35L" Drug 1014_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.16E-09 1.82E-04 1.29E-06 1.45E-05 47 170 "ARNTL,ST3GAL5,SCAPER,BAIAP3,SPAG9,CLGN,AKAP12,PDE4DIP,DOCK4,ARMCX2,JAKMIP2,MBNL2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,TDRKH,STON1,GRM8,PADI2,LSS,MITF,MPP2,MXI1,NEK1,PCDH9,SERPINI1,PKIA,GRAMD1C,PRPH,SGK1,SH3BGR,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,SLC17A7" Drug 2881_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.22E-09 1.85E-04 1.29E-06 1.45E-05 49 181 "ABHD6,NME5,SEMA6A,ALCAM,SRPX,APAF1,ARNTL,MARK4,ST3GAL5,RAB29,CLGN,UBE2L6,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,OPTN,MBNL2,RASGRP2,STX2,FYN,RUNDC3A,STON1,TPPP,KCNH2,MAP2,MITF,MXI1,TMOD2,SERPINI1,PRPH,PTCH1,SH3GL3,ASAP3,ARHGEF40,LIMCH1,ELOVL4,RGL1,STXBP1,WSCD1,TRIM2,HEY1,RUNDC3B,SSBP2,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 6726_UP Ioversol [87771-40-2]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "ASPHD1,APC,CDC14B,PPP4R4,SLC4A4,FUBP1,CAMK2A,SLC16A4,SCARB1,FOXN3,CABP1,VCAN,CYBB,INTS1,DTNA,EDIL3,HIPK3,ELN,ETV1,FGF1,EFCAB2,OGA,GPR75,SHISAL1,IL12A,KCNJ5,LAMA2,LMO2,MMP16,NF1,NTRK2,P2RY1,PALM,GPR85,PPARA,MAPK10,CNNM2,PTPRG,ENOX1,RGS12,CCDC102B,PREX2,SNCA,CEP68,TCF4,PCDHGA10,PCDHA6,CABIN1,XRCC4,EMSY,DPF3,SENP7" Drug 3175_DN Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "ALCAM,APBB2,APC,FAM131A,MARK4,NCOA1,ATP6V0A1,SCAPER,MTMR2,MAGI1,TAOK2,CDC42BPB,AKAP12,CRY2,PDE4DIP,GREB1,TOM1,ENO2,ERBB2,FECH,FGFR1,FHL1,SYT17,DISC1,MALT1,POLL,GPD2,CNTRL,SPACA9,BTN2A1,ITPKB,KCNH2,PMP22,PRKACB,MAPK7,RIPOR1,CEP97,RGS3,ZNF821,BTBD7,ZHX3,ZBTB43,STX1A,MTCL1,TRIM2,DOCK9,ZNF34,ZKSCAN5,HIRA,REEP1,HPS4,EPM2A" Drug 2580_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "RALGAPA1,TRMT9B,CDC42BPA,APAF1,APBB2,CDC14B,CDK13,MARK4,NCOA1,KIF1A,BCL7A,MTMR3,LDLRAD4,CD38,CHN2,TAOK2,RAB33A,HOMER3,AKAP7,FAM149A,BAG4,CREM,SIPA1L1,RUBCN,FCF1,TUBD1,PDLIM5,CSPG5,MSL3,RAB40B,DIDO1,ATXN2L,LIG4,SMAD1,MAP4,MEF2C,AFDN,SLC11A2,PIK3R1,CCSER2,SLC25A23,TMEM231,RNASEL,RASA3,SH3BP2,FBXO11,CNKSR2,SLC2A5,SPTAN1,ARHGEF9,CRTC1,PLSCR4" Drug 6843_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "SEMA6A,SEMA7A,APLP1,APOC1,LGR5,MARK4,SCAPER,CACNA1I,BAIAP3,CACNB4,HAP1,ARHGEF1,TAOK2,VAX2,CNN3,PICK1,CPS1,NCOR2,ARHGEF10,CNTNAP2,DCAF4,MAML1,DGKG,ACSL4,ZNF589,FHL1,FYN,SRCAP,GFER,GRM8,AP4S1,RASSF8,KCNQ3,MID1,NPTX2,ENPP2,MINDY2,PRKAR1B,MAPK7,CEP97,TCP11L1,EMID1,RASA3,ASAP3,CCDC88A,TSNAXIP1,CLSTN2,WSCD1,UGT8,VLDLR,SPHK2,NT5M" Drug 7386_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "ABR,MTUS1,BCAS1,SHROOM2,ATP2A2,ATP2B2,ADAM23,BACH1,CACNA1A,HAPLN1,USP6NL,RUSC2,FCF1,ETV1,RRAGB,CGREF1,SEPT9,POLL,LPAR4,GRIN2C,HSF2,SHISAL1,TJAP1,IL12A,FAM69A,KCNJ5,MAN2A2,TAGLN3,CNOT4,NOVA1,SLC11A2,FA2H,POU6F1,LRRN3,PPP5C,TMEM231,EMID1,SH3BP2,ARHGAP26,SPTAN1,DDN,SMG6,GPR161,R3HDM1,CABIN1,TRIO,ZKSCAN5,FAM155A,FLRT2,ZNF74,MPPE1,PARP11" Drug 6983_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "ABHD6,ADORA1,AP2A2,SRPX,APC,EPB41L5,BCAS1,CDK10,PRX,CFLAR,SYNJ2,BAIAP3,ARHGEF1,AKAP7,NECTIN3,VCAN,DZIP3,GPRASP1,TBC1D5,GIT2,DBN1,PHF20L1,EIF5,ENO2,NCALD,ANKMY1,RRAGB,FECH,FHL1,GAD1,ERAP1,POLL,HMGCR,INPP5B,LMO2,MEIS2,AFDN,MMP16,MPP2,PDPK1,LRP12,RELN,PTPRD,RIPOR1,GTDC1,RGS3,SBF1,PKNOX2,VPS13A,IQCE,ZNF74,MARCH8" Drug 6681_DN Etoposide [33419-42-0]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "TRMT9B,AMT,CDC42BPA,APAF1,SEMA4G,ST3GAL5,SCARB1,CACNA2D2,NRXN3,PICK1,CSF1,ARHGEF4,RIMS2,PLXNC1,EIF5,TNK2,ZNF391,ETV1,HPCAL4,SEMA4D,DCTN2,ERAP1,HLF,LIFR,MPP2,LYRM9,NDP,NOVA2,PDE4D,GPSM2,PLXNB1,FAT4,KCTD17,SUGCT,ZNF821,ZFP30,ASAP3,FHOD3,DZIP1,PREX2,IQSEC2,DDN,TBCEL,IQCE,ZEB1,SYNE1,DOCK9,TNS1,TRIO,XRCC4,REEP1,NAV3" Drug 6495_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "AK2,SEMA6A,AMPH,PPP4R4,N4BP2L1,NRP2,CAMK2B,CDH2,TPP1,CNTN1,AKAP7,RASSF2,DAPK1,SPOCK2,ARMCX2,HEPH,ECM2,EPHB1,DLC1,FGFR3,FHL1,AGAP2,DENND2A,SIGLEC8,GSTM5,SOX21,SHISAL1,LSS,MBD1,MID1,ADAM22,TAGLN3,MYO7A,NTRK3,PALM,SEPT4,PPP5C,PTPRB,KCTD17,NUDT11,TSNAXIP1,SP2,ARHGAP26,ARC,EXOC7,TRIM2,DOCK9,TLR4,TNS1,UGT8,WIPF1,XRCC4" Drug 3984_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "NDRG2,ADD2,SEMA7A,PKP4,CDC14B,CDK10,ADAM23,ADAM15,CFLAR,MTMR3,BAIAP3,LDB2,CBFA2T2,CNTFR,AKAP7,WHRN,AKAP5,PDE4DIP,EDNRA,HIPK3,NRN1,HPCAL4,TRMO,OGA,SRCAP,STON1,MCHR1,IL12A,KCNN1,DUSP26,PILRA,SUSD4,STK32B,FUZ,PEX26,SLC11A1,ZNF334,ZHX3,SMG6,SZT2,CHST8,GPR161,SLC44A1,R3HDM1,TPM1,HIRA,TUBB1,VGF,VIPR2,LAT2,NT5M,PHTF2" Drug 4428_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "NDRG2,BEGAIN,PDE8B,ATP2B2,KIF1A,LDLRAD4,CACNA1A,CAMK2A,CAMK2B,SEPT7,RAB33A,SUSD5,PDE4DIP,SNPH,CDON,EDN3,RASGRP2,CORO2B,DLC1,PDLIM5,DISC1,SRCAP,LYVE1,GLI2,CACFD1,ICA1,IRF8,IL6R,LAMA2,NELL2,NF1,POU6F1,PPP5C,CEP41,MAPK7,PTPRN2,ACSS3,SUSD4,RASGRF1,RGS12,HKDC1,CNKSR2,CXXC4,PDZRN3,ZNF423,TACR1,MCF2L,KLHL4,OBSL1,SLC44A1,BHLHB9,TRO" Drug 6592_DN "16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "NDRG3,EP400,KCNAB2,APOC1,CDK10,RAB26,HDAC9,DPH1,STX2,ANKMY1,NBEA,SYT17,USP19,HTATSF1,GPER1,RASSF8,INPP5B,LIFR,MAPT,MEF2C,MX1,ZNF862,NFIX,NPR2,CCSER2,GRAMD1C,CNNM2,SAMD9,BCAS3,PTCH1,PTPRN2,GAL3ST4,NEK11,FBXW7,RPS6KA2,MAPK12,SH3BP2,SLC14A1,SMARCD3,IQSEC2,POGZ,PLCB1,OBSL1,CHST8,TNS1,CHST5,UBTF,PLPPR2,LAT2,KLC2,TRIM9,NT5M" Drug 4093_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.50E-09 1.97E-04 1.29E-06 1.45E-05 52 198 "ADD2,AP2A2,ADGRF5,SYNJ1,ST3GAL5,SYNJ2,IL33,CACNA1A,PLEKHB1,ARHGAP22,RAB28,RAB26,AKAP7,ENTPD4,AATK,CSF1,ARHGAP32,DAPK3,BRINP1,MFAP3L,RUSC2,EXOG,EDN1,MTSS1L,ZNF549,ETV1,FGFR1,DLL3,ZNF44,TRAF3IP2,GLYR1,GNAL,SYNPO,HNMT,MPP2,SERPINI1,PPARA,PRPH,SAMD9,GSTCD,RPS20,DZIP1,ZNF415,SPTAN1,MCF2L,TRIM2,TK2,TRIO,HIRA,WIPF1,XRCC4,EMSY" Drug 992_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.65E-09 2.04E-04 1.32E-06 1.49E-05 48 176 "NME5,ARNTL,ST3GAL5,SCAPER,BAIAP3,CLGN,AKAP12,PDE4DIP,DOCK4,ARMCX2,JAKMIP2,TSPAN5,EDNRA,OPTN,STX2,FYN,RAB40B,TDRKH,STON1,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,PKIA,PRPH,RPS6KA2,SH3BGR,SH3GL3,PPM1E,SYBU,WDR47,FAM214B,SLC6A8,SLC22A4,TSPYL2,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,ZNF45,REEP1,SLC17A7" Drug 6789_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-09 2.21E-04 1.40E-06 1.58E-05 51 193 "RALGAPA1,ASPHD1,ASIC1,AMT,APC,PPFIA3,DNAH17,ALDH7A1,ADAM23,CFLAR,MTMR3,BAIAP3,CLGN,AKAP5,PDE4DIP,GREB1,PPP6R2,SNPH,MBNL2,ING4,MRNIP,ERCC2,AGAP2,NSG1,CPLX2,GFER,CNTRL,IL6R,KCNJ5,MGAT3,ZNF862,FXYD7,NF1,NPTX1,NLE1,PNMA8A,KCNIP1,SH3BP2,ASAP3,FAM214B,SNCA,ZNF423,SPTB,SYP,DMXL2,CRTC1,CHST8,GPR161,ZNF34,FAM155A,ITM2C" Drug 3791_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.11E-09 2.24E-04 1.40E-06 1.58E-05 47 171 "ABHD6,MTUS1,APAF1,CDC14B,ARNTL,ADGRB2,ST3GAL5,SYNGR3,NRXN3,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,BAIAP2,FYN,PCDH17,STON1,TPPP,GUCY1B1,KCNH2,LIFR,MAPT,KITLG,MMP16,MMP17,TAGLN3,FXYD7,NPTX2,PCDH9,ENPP2,SERPINI1,FXYD1,ENOX1,RGS4,FBXW7,ASAP3,THSD1,ELOVL4,RGL1,SYT1,COBL,OBSL1,SSBP2,TRIM9,SLC30A3" Drug 4691_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "AMPD3,GAS7,SLC4A4,ATP2A2,CFLAR,GYG2,CA4,CAMK2G,KRIT1,USP2,SEPT7,QKI,HOMER3,CNTN1,CRMP1,RGS6,FAM169A,ARMCX2,SPOCK3,EXOG,RASGRP2,FGF12,SRCAP,RAB30,PCLO,GRM8,INPP1,KIT,MAP2,ADAM11,KITLG,MMP16,MYT1,PDE4B,PDPK1,SERPINI1,SLC25A23,STRN3,PPP5C,MAPK7,ELOVL2,GSTCD,KCNIP1,RASA3,FBXO11,CCDC88A,SLC11A1,LIMCH1,RBM34,CLSTN2,PHLDB1,RUNDC3B" Drug 5509_UP Resveratrol [501-36-0]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "ADRA1D,BEGAIN,CDC14B,ARHGDIG,PLA2G4C,RASL11B,N4BP2L1,KSR1,ASIC3,CNR1,CNTN1,CSF1R,ARMCX2,EGR3,MTSS1L,SPEG,BAIAP2,TPK1,GNAO1,GRIK5,DHX35,KCNH2,MBD1,GIT1,MX1,NFYA,PALM,CDK18,PFKFB2,PLEC,POU6F1,PRODH,ELOVL2,ZDHHC14,NEK11,TCP11L1,RPS6KA2,MAP6D1,EMID1,SBF1,RASA3,ARHGEF40,KIF13A,ZC3H13,SPTAN1,SYN2,MCF2L,TAL1,TK2,CABIN1,ZNF45,SEMA3B" Drug 6622_DN Cefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "NME5,TRMT9B,CDC42BPA,PPFIA4,CDK13,DNAH17,CACNA1A,LARGE1,TAOK2,RAB28,WHRN,CSF1,CNTNAP2,MFAP3L,CDON,FEM1B,SUGP2,TNK2,EZH1,CGREF1,ZNF44,GAD1,POLL,LPAR4,GRM8,TJAP1,IL6R,IL6ST,INPP5B,MAP4,MAPT,MEIS1,AFDN,POLG,WDR25,PTN,KIRREL1,ZNF821,KDM4D,ZNF667,ZBTB43,DDN,SPART,SYT1,KLHL4,SZT2,DOCK9,THRA,BHLHB9,TNS1,TRIO,TIGD6" Drug 2739_UP Iopromide [73334-07-3]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "TRMT9B,AZGP1,ADGRB1,KSR1,CACNB4,DGKI,CDH2,LARGE1,DLGAP1,CABP1,NCOR2,PDE4DIP,INTS1,BRINP1,MFAP3L,HEYL,MBNL2,AASS,FAM198B,TBC1D16,FGFR3,ZNF44,GAD1,MAPT,MBNL1,MID1,AFDN,ADAM22,NTRK2,SEPT4,PPP1R1A,KHDRBS2,SUGCT,SCN2B,SCN8A,MRAS,NLGN1,ZNF415,HECW1,SSTR2,PCDHGB6,DOCK9,PHF24,TRIO,AMACR,LMF1,KLC2,XRCC4,SPHK2,EVI5,SEMA3B,TIGD6" Drug 5515_UP Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "C1QTNF1,AMH,APBA2,CDC14B,CDK10,SEMA4G,CHRD,ADAM23,SYNJ1,GYG2,CACNB4,CNTFR,WHRN,SIPA1L1,VCAN,CNTNAP2,ARMCX2,SLC12A6,ECM2,EDNRB,NRN1,FER,AFF2,EFCAB2,ERGIC3,FYB1,SOX21,KCNH2,KCNN1,IPO5,MN1,TAGLN3,ZNF862,CLDN11,PAX6,POLG,PPARA,RELN,ZSCAN32,RASGRF1,ZDHHC14,SALL1,SH3GL3,CCDC88A,PDZD2,SOX11,HECW1,ARHGAP26,ATP10B,DOCK9,PLPPR2,XRCC4" Drug 4485_UP Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "ADD2,ADGRF5,APAF1,APBB2,EPB41L5,PRX,BMP7,FUBP1,GYG2,KALRN,LHX2,STOML1,CLTB,FAM189A2,CNTFR,HAPLN1,CSF1,DMD,DTNB,EDIL3,CELSR3,TENM1,ETV1,ARMCX1,DLC1,KAT8,NSG1,ZNF44,ZNF276,GNAL,PRUNE2,GRIK5,HLF,MAN2A2,ADAM22,PFKFB2,MAPK7,ZSCAN32,RET,RGS4,SCN8A,CNKSR2,SPTAN1,LHPP,TNS1,VAV1,VGF,SPHK2,ZBTB38,ZNF225,HPS4,JPH3" Drug 5048_UP Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "ASIC1,AK2,APAF1,APC,GAS7,APOC1,CDK10,SEMA4G,PPP4R4,MADD,CDK13,BMP7,ASIC3,RAB26,IQCK,DBT,ELN,COQ7,SPEG,PTK2B,FGF1,FGFR1,FAM49B,SYT17,GNG4,GPER1,GRIK5,GRM8,KCNN1,MATN3,KITLG,NF1,OCRL,PDE4B,RETREG1,PPP5C,GRAMD1C,PTPRH,PID1,PKNOX2,ZHX3,IZUMO4,ARHGAP26,ATP10B,PLCB1,COBL,SZT2,DOCK9,DNAH7,SLC44A1,MKRN3,KCNAB1" Drug 6524_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "NME5,AK2,BEGAIN,AMPD3,GAS7,PLA2G4C,ADAM23,NRP2,CA4,CAMK2G,USP2,ARHGEF1,CLGN,PLEKHB1,COL9A3,MAML1,SLC12A6,RCAN1,DTNA,HIPK3,ERCC2,NRN1,CORO2B,OLFM1,FHL1,GALC,ERAP1,ALDH1L1,TDRKH,GSTM5,SOX21,RASSF8,HLF,HNMT,KCNH2,KPNA5,MAP4,MAPT,MSI1,NLE1,LRRN3,RNASE1,SBF1,CNKSR2,SNCA,TAL1,HIF3A,SLC44A1,CABIN1,WIPF1,WNT7A,XRCC4" Drug 2689_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "C3orf14,MTUS1,ADGRF5,SYT13,SEMA4G,CASK,ATP1A3,KSR1,FUBP1,CALB2,NDST3,CABP1,COL9A3,CREM,NCOR2,ARHGEF10,SUSD5,SIPA1L1,PDE4DIP,GREB1,USP6NL,DRP2,RCAN1,HIPK3,SRPK3,F5,FER,SIGLEC8,GRIN2C,RASSF8,KCNN1,AFF1,ADAM22,NEFM,PPP1R1A,RASGRF1,SUGCT,HKDC1,SLC11A1,SNAP25,ARC,SYT5,KIAA1107,PHF24,TIAM1,TRPS1,UBE3A,VSNL1,KCNK12,EVI5,HRASLS,JPH3" Drug 3701_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "ADORA1,AGT,ALK,DOC2A,BIN1,APOC1,RASL11B,ADGRB2,LARGE1,TAOK2,STOML1,CNTFR,KIAA0586,MAML1,DMPK,CDON,EDIL3,PLXNC1,EIF4G2,ETV1,FGF1,FYB1,NEU3,SRCAP,POLL,IRF8,KIT,SMAD1,MAP2,MAPT,MARK1,SCAMP5,ADAM22,TAGLN3,NF1,CNOT4,CEP41,WDR25,PTPRB,RGS12,TCP11L1,SBF1,MRAS,SMARCD3,ZHX3,DDN,ASTN2,MCF2L,HIF3A,AP4E1,RPRM,KLC2" Drug 3546_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "BRAP,SEMA6A,ATP1A3,SCAPER,GYG2,CACNA1I,CA4,KALRN,CAST,RCBTB2,FOXN3,SLIT2,CNTNAP2,DUSP9,EDNRB,HIPK3,C3orf18,RASGRP2,CHL1,ERAP1,TMEM8B,DISC1,GNAO1,TDRKH,LILRA2,GPR37,KCNJ5,KIFC3,LAMA2,SMAD1,MARK1,MSR1,NF1,NPY,NOVA2,NTRK3,PLCD1,TMEM255A,ZNF821,SH3BP2,PKNOX2,KDM4B,TSNAXIP1,ZSWIM8,SPTAN1,WSCD1,PCDHA2,CHST5,AMACR,PDIA2,SLC30A3,ADAMTS9" Drug 4259_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "RALGAPA1,MTUS1,SHROOM2,CDK13,SLC4A4,ST3GAL5,ARHGEF7,SCARB1,CHN2,CNOT8,QKI,ENTPD4,PDE4DIP,TBC1D5,PLPPR4,PARD6A,DPH1,RGS17,VPS13B,COQ7,ETV1,RRAGB,FER,DENND2A,GLI2,GLYR1,KCNMB4,CNTRL,SHISAL1,FAM69A,INPP5B,JAK2,TM6SF1,NDP,RETREG1,PTCH1,PTN,ZSCAN32,PTPRN2,RAD51D,GTDC1,GSTCD,CSRNP3,FBXO11,FNDC3A,PLCB1,KIAA1107,ZNF34,SSBP2,VGF,WIPF1,KCNAB1" Drug 3206_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "NDRG2,AK2,GAS7,PRX,MARK4,PROM1,CFAP410,CA4,CALB1,CAMK2B,CBFA2T2,CNN3,WHRN,ARHGEF10,SIPA1L1,ARHGEF4,MFAP3L,DUSP9,EGFR,TNK2,NRN1,ZNF44,DENND2A,ERAP1,MSL3,IRF8,MAP4,MAPT,GIT1,PCDH8,SLC25A23,PTPRO,KLHDC8A,TCP11L1,SEMA6D,ASAP3,PREX2,PKNOX2,SLC6A8,SLC22A4,OGDHL,SNAP25,PHF24,SLC19A3,GPR161,TK2,CABIN1,TRPM2,FAM155A,XRCC4,DNALI1,PHTF2" Drug 5944_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-09 2.38E-04 1.40E-06 1.58E-05 52 199 "AK2,ALCAM,LTBP4,ALK,CDC42BPA,GAS7,MARK4,CFLAR,BAIAP3,CA4,ASIC3,RAB33A,COL9A3,NRG2,SH2B1,SOCS5,RIMS2,EGFR,MTSS1L,CORO2B,GALC,DISC1,SRCAP,RUNDC3A,SYNPO,HNMT,ICA1,LMO2,SMAD1,MAPT,MEF2C,NFYA,NNAT,PLTP,CEP41,RNASEL,NEK11,FUZ,CNKSR2,EPN2,HECW1,ARHGAP26,SPTAN1,PHLDB1,STX1A,TMEM121,GPR161,FAM155A,VSNL1,ITM2C,EPM2A,SMIM8" Drug 4768_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.69E-09 2.49E-04 1.46E-06 1.64E-05 48 177 "ADRB2,NME5,APAF1,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,NECTIN3,AKAP12,PDE4DIP,DZIP3,ARMCX2,TMCC2,OPTN,FAM13A,ENO2,RASGRP2,FHL1,HPCAL4,FYN,CYP46A1,STON1,MEF2C,MPP2,TMOD2,SERPINI1,PLCD1,GRAMD1C,PRPH,RADX,NUDT11,SH3GL3,ASAP3,FAM214B,PEG10,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,TNS1,RUNDC3B,SSBP2,SLC30A3,SLC17A7,ITM2C" Drug 2965_UP Iopanoic acid [96-83-3]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.09E-09 2.67E-04 1.54E-06 1.74E-05 51 194 "MTUS1,ADGRF5,CDC42BPA,GAS7,MARK4,BMP7,CACNA1I,BAIAP3,LDLRAD4,CACNA1A,CDO1,TAOK2,HOMER3,SH2B1,CSF1,ARHGEF10,PDE4DIP,PPP1R16B,ZNF337,DBT,CELSR3,C3orf18,POLL,GSTM5,MAN1B1,KCND1,MAP4,AFDN,CNOT4,NRCAM,CCSER2,PLEC,POU6F1,TCP11L1,EPN2,SLC11A1,BTBD7,TSNAXIP1,SPTAN1,SPART,CLSTN2,PDLIM2,OBSL1,TNS2,CRTC1,TEK,TNS1,CDK20,VIPR2,URM1,MPPE1" Drug 4082_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.09E-09 2.67E-04 1.54E-06 1.74E-05 51 194 "ADORA1,C1QTNF3,LTBP4,SEMA7A,PKP4,ADGRB2,SCAPER,CA12,CAMK2B,RUNX1T1,SCARB1,RAB33A,STOML1,CNTN1,FAM149A,ARHGEF4,DAPK1,JAKMIP2,SHANK1,SEMA3D,NCALD,PTK2B,FGFR1,PRELID3A,DISC1,ADAM28,PCDH17,GNAL,ATXN2L,IGF1,SCIN,KCNH2,KITLG,NF1,PCBP3,PCDH9,CEP41,ELOVL2,CRTAC1,RET,RGS12,GSTCD,KCNIP1,ZNF334,SLC14A1,KIF13A,SPTB,MCF2L2,DMXL2,TNS1,DPF3" Drug ctd:D015655 1-Methyl-4-phenylpyridinium CTD 6.23E-09 2.73E-04 1.57E-06 1.77E-05 263 1659 "ABR,ASPHD1,ACADM,ACHE,AS3MT,ELFN2,ADORA1,ADORA2A,SLC24A4,AGT,OSBPL1A,ALCAM,GPRASP2,SYT13,AMH,AMPD2,APC,VAT1L,SFMBT2,ZBTB10,NCOA1,ATP1B3,ATP2B2,ALDH7A1,ADGRB2,ADGRB3,HCN2,BCS1L,PROM1,FUBP1,LDLRAD4,CA4,CALM1,SLC25A14,CARS,RUNX1T1,CBS,KYAT1,CD86,ARHGEF2,SEPT7,CDH2,DCLK1,LARGE1,MAGI1,CDO1,CDR1,TBRG4,CLGN,COPB2,CHN2,NRXN3,TPP1,FAM19A5,MAP4K4,CNTFR,FAM149A,COX4I1,FAM171B,RBM39,CS,LRIG1,VCAN,PLXNA4,SLITRK5,CTH,CYBB,MATR3,SPOCK2,AIF1L,DBN1,JAKMIP2,ZNF804A,TIAM2,LYPD1,SPOCK3,KIF19,CHRDL1,RAB39B,HS3ST2,SLC29A4,ARRDC4,FARSB,ABCC5,DNM1L,EBF1,EDIL3,SEMA3D,TMTC1,TMEM132E,HSD17B14,MTSS1L,MRPL10,TBC1D16,ACSL4,TUBA1B,TUBB3,RACK1,FCGRT,FDFT1,OLFM1,FGF11,FGF13,AMOTL2,ATP5PD,PCYOX1,SYNCRIP,FLNC,NOP56,SYT3,TPPP3,GAA,MTHFD2,SRCAP,NFU1,PCDH17,PPARGC1A,RAB30,GPT2,GPR37,GRB10,GRIA2,C1QL4,GRIN2D,FAM222A,UBE2QL1,PADI2,ELOVL5,SYNPO,HMGCL,NEGR1,HSPA1L,SHISAL1,SOWAHA,IGF1,TMEM240,SLC6A17,ITGAM,KCND2,KCNJ5,KCNK3,TTYH2,LAMP2,LSAMP,GPR155,MAPT,LRP1B,MMP16,MMP17,FXYD7,HNRNPM,NCAM2,NEFM,NELL2,NFE2L2,ALDH1L2,NNAT,NOVA1,NPTX2,OPRL1,PCDH9,CDK18,PDCD2,TMOD2,PKD1,PKM,PLCB2,PLXNB1,PSAT1,ING3,SH3KBP1,DRAM2,IRX1,PPP1R1A,PPP2R2B,LRRN3,MAPK3,EPDR1,MAPK7,MAPK9,MAPK10,PSD,NCR3LG1,PTN,PTPRH,PTPRN,PTPRO,MARCH1,C1orf54,FAT4,RBBP6,RET,FIGN,RNH1,KLHDC8A,FBXW7,LRRK2,MEG3,TUNAR,KCNIP1,MAPK12,SARS,CSRNP3,FNIP1,TRA2B,SHMT2,R3HDM2,CCDC92,SLC9A5,SLC12A4,TET1,SMARCC2,SNCA,FAIM2,SNRPN,KDM3A,SPP1,UNC5B,SPTAN1,NFASC,LMO3,CLSTN2,SST,NKAIN2,STAC2,SUPT5H,PRRC2C,SYNE2,ANKRD28,C12orf76,MLST8,KLHL4,WSCD1,KIAA0930,CUX2,PCDHB4,SIRT1,CHST8,NACC2,ICAM5,ASXL3,TLR4,ANKRD24,TNS1,RASD2,TPM1,PDIA2,FLRT2,VGF,RBFOX3,XPO1,SLC47A2,PCDH20,ZNF708,KCNT2,ELFN1,CRB2,TMEM178A,HRASLS,FAM13C,RTN4,HNRNPA3,FXR1" Drug 1504_UP Khellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.54E-09 2.87E-04 1.62E-06 1.82E-05 52 200 "NDRG2,ADORA1,C1QTNF1,SRPX,LTBP4,AMT,CDC42BPA,PRX,CFLAR,SCAPER,MTMR2,CACNA1I,HAP1,CAMK2B,CLGN,TAOK2,RCHY1,NECTIN3,LYPD1,DTNA,EDNRA,FEM1B,PLXNC1,EIF5,VPS13B,STX2,ZNF589,FHL1,PDLIM5,GUCY1A1,KCNH2,MBD1,SETD4,CDK18,PLCD1,PRKAR1B,ZSCAN32,ZDHHC14,SH3BP2,FRMPD1,PEX26,IQSEC2,SAMSN1,SYN2,CRTC1,THRA,TK2,BEX4,CDK20,WIPF1,XRCC4,SLC17A7" Drug 3779_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.54E-09 2.87E-04 1.62E-06 1.82E-05 52 200 "SYN3,APBB2,APC,ATP2B2,KIF1A,RGS9,GYG2,CFAP410,CALB2,CH25H,SULT4A1,AKAP6,NCOR2,ABCG1,RGS6,LRIG1,RIMS2,INTS1,SPOCK3,EBI3,MRNIP,GABRB3,GNAL,GNAO1,SOX21,IRF8,KCNN1,KCNQ3,CNOT4,NPY,NTRK2,NTRK3,PCDHGC3,PDE4A,GPR85,PLXNB1,MASP1,PTPRH,PTPRO,RET,ASAP3,SLA,KANSL3,UNC5B,SPTB,TACR1,DOCK9,OBSL1,TEK,ICAM5,PDIA2,NLRP3" Drug 7204_UP Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.54E-09 2.87E-04 1.62E-06 1.82E-05 52 200 "ADORA1,ADORA2A,BIN1,APAF1,APBB2,GAS7,ARRB1,MARK4,ATP6V0A1,GYG2,CACNA1I,LDLRAD4,B4GALT6,SLIT2,SULT4A1,AKAP7,RCHY1,BAG4,NCOR2,SLC12A6,DTNB,MBNL2,SPEG,F5,FGFR1,ANKFY1,DOT1L,OGA,FYB1,GPD2,ADAMTS13,GRM8,SYNPO,IL6ST,KIFC3,LIG4,KITLG,MSI1,MYCN,ENPP2,TMOD2,NECAB2,PRKAR1B,PRPH,ELOVL2,SH3BGR,ASAP3,TTBK2,EXOC7,DMXL2,TRIM2,DNALI1" Drug ctd:C014024 "2,4,5,2',4',5'-hexachlorobiphenyl" CTD 7.02E-09 3.08E-04 1.73E-06 1.95E-05 286 1835 "ABR,AXIN2,FZD9,USP31,TEX22,ADGRF5,SEMA6A,SPOP,ALCAM,AMH,OGT,CDC42BPA,DPP10,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,PPFIA3,PRX,CADPS,ASPA,CCDC74A,PTCH2,ZBTB10,ATP2B2,DOCK11,AZGP1,BARD1,RGS9,LDHD,ARHGEF7,AP1M1,GPC2,IL33,CA8,CA12,LURAP1,CALB1,CALB2,CALM1,KALRN,CAMK2A,CAMK2B,PRC1,CLDN10,CCK,LRBA,CDC25B,L3MBTL4,MAGI1,CRLF1,CHN2,PLEKHB1,NRXN3,COX4I1,NSL1,CLOCK,ENTPD4,AKAP12,CSF1,IPCEF1,PDE4DIP,CNTNAP2,CST3,PLCXD3,GREB1,CYBB,DGKG,DAPK1,DBN1,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,SGSM2,DMD,HS3ST2,CDON,SHANK1,CASP8AP2,DTNA,DTNB,DUSP9,EBF1,SNX29,RASGRP1,FRY,CELSR3,PHF20L1,EGFR,PLXNC1,TMEM132E,PLEKHA1,ENO2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,TUBB3,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,AGAP2,ZMYND15,FOXO3,FLT1,SMC2,CAMKK2,CELF1,GAA,GALNT15,GABRG2,ZNF274,DISC1,SRRM4,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,TOX3,GLUL,MAP7D2,GNAL,GPD2,PRUNE2,GPR37,CNTRL,GRIN2C,ZNF496,RNF165,GSTT2,ZBTB49,BVES,HAS2,HMGCR,HNF4G,IGFBPL1,IRF8,MYLK2,SOWAHA,IGF1,NKD1,KNDC1,DISP2,INSM1,ITGA7,ITPKA,KCND2,KIF5A,STMN1,LIFR,MAP6,MEIS1,SCAMP5,ADAM22,MSR1,MT1M,MX1,MYCN,MYT1,NEFH,NELL2,NFYA,NME4,NOVA1,NPTX1,KSR2,GPR137C,PCDH9,CDK18,PRTG,PDE1C,PDE4B,ENPP2,ABCB1,NALCN,TMEM38A,KCTD15,FXYD1,PSAT1,NECAB2,PPARA,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,SPDL1,PTPRD,PTPRN2,PEX2,TUG1,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,TNFRSF19,SMPD3,PPM1E,HKDC1,ST6GAL1,ABLIM3,SLC8A1,ARFGAP1,OGDHL,RCOR3,FAIM2,FNBP1,SOX11,NMNAT2,SPP1,TEX2,UNC5B,ARHGAP26,MESP1,SST,NKAIN2,ADHFE1,NECAB1,SYNE2,SYP,ANKRD12,MCF2L,PDLIM2,SATB2,ZEB1,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,THRA,MTMR14,TIMP4,RELL2,ASXL3,TLR4,DOK6,TTC3,CLHC1,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,TUBA1A,RGS7BP,FAM13C,ACTR3B,AP3B2,ST8SIA2,SPATA13,JPH3" Drug 4200_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.35E-09 3.22E-04 1.78E-06 2.01E-05 51 195 "APC,SHROOM2,CDC14B,RASL11B,NRP2,SCAPER,CFAP410,RUNX1T1,CHN2,HOMER3,ERC2,CTH,DOCK4,SGSM2,DTNA,ECM2,EDIL3,HIPK3,COQ7,EPHB1,PTK2B,ZNF589,IQCG,FLT1,ANKFY1,PDLIM5,CSPG5,DISC1,ADAM28,GNAL,GPER1,IL6ST,LIG4,MARK1,KITLG,NF1,NTRK2,PCDH9,RETREG1,PLCD1,PTN,PTPRG,PTPRN2,SH3TC2,FAT4,RGS3,RGS4,KCNIP1,KIAA1107,SLC17A7,HRASLS" Drug 3553_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.35E-09 3.22E-04 1.78E-06 2.01E-05 51 195 "C1QTNF1,SPARCL1,BIN1,CDC42BPA,KCNAB2,BCAS1,RGS9,MTMR3,CACNA1I,HIP1R,EPS15L1,HOMER3,PICK1,AATK,RGS6,OSBPL3,ARHGEF4,BRINP1,SPOCK3,DMPK,FGFR3,GLYR1,GRM2,GUCY1B1,IL6ST,KCNN1,SMAD1,MID1,ADAM22,NF1,NOVA2,PDE4B,POU6F1,PTPRB,C1orf54,ZFHX4,SUGCT,RPS6KA2,COA1,SPTAN1,DDN,ATP10B,TROVE2,DMXL2,DOCK9,TNS2,PCDHA6,SLC44A1,PIK3R5,DNALI1,JPH3" Drug 6626_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.35E-09 3.22E-04 1.78E-06 2.01E-05 51 195 "ADD1,ADRA1D,C1QTNF1,ALK,EPB41L5,GAS7,ALDH7A1,CFLAR,BAIAP3,RUNX1T1,ARHGAP33,AKAP5,RCHY1,SPOCK2,DTNA,DTNB,EDN1,HIPK3,EGFR,VPS13B,ZNF391,ETV1,DLC1,FGF1,PRELID3A,RUNDC3A,GPD2,GSN,ELOVL5,ICA1,IL6ST,KIT,MAP4,KITLG,PCDH9,PFKFB2,PRPH,ZSCAN2,C1orf54,KCTD17,PNMA8A,SCN8A,SUPT20H,ASAP3,SLC11A1,DOK5,PHLDB1,CRTC1,CHST5,LAT2,DPF3" Drug 1672_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.67E-09 3.36E-04 1.85E-06 2.08E-05 47 173 "SEMA6A,ALCAM,APLP1,MARK4,ST3GAL5,RAB29,CLGN,ARMCX2,TSPAN5,OPTN,MBNL2,STX2,ACSL4,FYN,CYP46A1,RAB40B,STON1,GPR37,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PMP22,PKIA,PRPH,PTCH1,FAM184A,GSTCD,SH3GL3,PPM1E,ASAP3,WDR47,SMARCD3,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,RPGRIP1L,HEY1,RUNDC3B,SSBP2,REEP1,GDPD5,SLC17A7" Drug ctd:C013418 bromfenacoum CTD 8.30E-09 3.64E-04 1.99E-06 2.24E-05 122 645 "ADD1,CASKIN1,AGT,SORCS2,ALCAM,SEMA7A,PKP4,APC,GAS7,ATP1A3,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,DST,WASF1,CACNA2D1,CALB1,CALB2,CALM1,CAST,CBS,CPNE6,HECTD1,HOMER3,CNN3,PICK1,CNTN1,HAPLN1,CS,ARHGEF10,VCAN,FAM169A,PNPLA8,RIMS2,FAM131B,SNPH,MATR3,SCRN1,SPOCK2,DBI,MTX3,FAM107B,SEC16A,PDCD6IP,FIS1,EEF1D,SUGP2,C8orf37,EIF1,MTSS1L,RACK1,BAIAP2,VTI1B,SPECC1,PDLIM5,ATP2C1,PRELID3A,ABLIM2,ALDH1L1,TCERG1,RNPS1,MAP7D2,TDRKH,STMN2,TPPP,DIDO1,PSIP1,PADI2,ATXN2L,AGFG1,IDH3A,SLC6A17,ITPKB,MAP4,MAP6,DBNL,NACA,NEFH,OPA1,PALM,PDE4D,OLA1,PLCD1,PLXNB1,RELN,CNNM2,ROGDI,RNH1,ELP2,SGSM1,MAP6D1,RTN1,NCBP3,FAM192A,ATXN2,HSPA4L,KIF21A,CPEB3,SHMT2,CCDC92,EPN2,SLC12A2,NAPB,LIMCH1,SPTAN1,MPRIP,STXBP1,SYN1,SYT1,CRTC1,SIK3,TST,OSBP2,CCDC136,TOM1L2,VSNL1,SPHK2,FIP1L1,RTN4,NHSL1,FXR1" Drug 4643_DN Iohexol [66108-95-0]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.85E-09 3.88E-04 2.07E-06 2.34E-05 51 196 "MTUS1,AMH,CDC42BPA,APC,DDO,PDE8B,ATP2B2,ADAM23,BAIAP3,CABP1,COL9A3,DTNB,EDN1,HEYL,MRNIP,MTSS1L,ANKMY1,F5,ST3GAL6,GAD1,SIGLEC8,SEPT9,GFER,LYVE1,POLL,ICA1,ADAM22,NOVA1,POLG,MAPK7,PTPRB,ZSCAN2,RGS12,ZNF821,SUPT20H,SLA,LIMS2,MYH15,SNCA,TSNAXIP1,DDN,FBXW11,THRA,TIAM1,AMACR,TRO,VIPR2,SPHK2,NT5M,EVI5,FAM13C" Drug 3986_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.85E-09 3.88E-04 2.07E-06 2.34E-05 51 196 "RALGAPA1,LTBP4,DOC2A,BIN1,SEMA7A,APAF1,PPP4R4,ADAM23,CACNA2D1,SCARB1,AKAP5,TBC1D5,EDIL3,HIPK3,PLXNC1,ING4,TNK2,ETV1,HPCAL4,OGA,STON1,GRM2,IL12A,KCNF1,KCNN2,MARK1,ADAM22,NRCAM,CLDN11,PGAM2,PNMA3,PRKAR1B,PTPRD,PTPRN2,ACSS3,BEND5,GSTCD,CSRNP3,PREX2,SLC14A1,OGDHL,SMARCD3,SOX15,ZHX3,HECW1,CRTC1,SLC44A1,HIRA,UCHL1,VGF,VIPR2" Drug 6074_UP Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.85E-09 3.88E-04 2.07E-06 2.34E-05 51 196 "AGT,ADGRF5,SEMA6A,ALK,BEGAIN,PLA2G4C,ATP1A3,ALDH7A1,N4BP2L1,GYG2,RHBDL1,CDH2,CRLF1,NCOR2,CSF1,CNTNAP2,RIPOR2,PARD6A,CDON,ERBB4,IGSF6,PTK2B,SCARA3,FYB1,FYN,ZNF44,LPAR4,ITGA7,ZNF862,NF1,P2RY1,TREM2,PFKFB2,MTRF1L,SAMD9,NUDT11,RPS6KA2,SLA,SLC2A5,IZUMO4,SPP1,SPTAN1,RGL1,SYT5,TACR1,WSCD1,CRTC1,PIK3R5,UCHL1,OSBP2,KCNK12" Drug 2097_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.85E-09 3.88E-04 2.07E-06 2.34E-05 51 196 "NDRG2,KCNAB2,APC,APOC1,PPP4R4,SLC4A4,ATP2A2,ALDH7A1,KIF1A,NRP2,HAP1,SCARB1,SYNGR3,RAB33A,ARMC8,SH2B1,FAM169A,ELN,SEMA4D,ZNF44,SIGLEC8,INPP5K,AHDC1,GLI2,GNG4,ICA1,MAPT,SCAMP5,GIT1,ADAM22,MSR1,PIK3R1,SEPT4,POU6F1,KCTD17,STUM,DZIP1,BTBD7,SNCA,KDM4B,SPTAN1,DDN,TACR1,CHST8,TIAM1,TLR4,CABIN1,VLDLR,TRIM9,ZNF74,KCNAB1" Drug ctd:C030935 benz(a)anthracene CTD 9.22E-09 4.04E-04 2.15E-06 2.42E-05 209 1264 "CLK4,ABHD6,ADORA1,ADRA1B,SPOP,ARHGAP20,FAM135A,OGT,LCORL,CPNE5,CDC14B,PPP4R4,ARNTL,ASGR1,ATP2A2,RGS11,RGS9,BMP7,DST,CACNA1I,C5,THSD7A,CAMK2G,KYAT1,USP2,SRSF11,CHRNA4,MAP4K4,AKAP7,ABI3BP,TOGARAM2,CLOCK,RBM39,CRY2,AATK,CSF2RA,OSBPL3,RASGEF1C,PITPNM3,GREB1,DCAF4,MYADM,TCAF1,RIPOR2,ELMSAN1,MTX3,NR1D2,ARRDC4,ABCC5,AASDH,EDN1,EDNRB,KLHL5,PHF20L1,EGFR,KMT5B,SRPK3,EPB41,ERBB2,IGSF6,CEP85L,REEP2,FAM198B,ZMYND10,POLR1B,POLK,ZMYND15,FOLR2,PDLIM5,TPK1,STAU2,DOT1L,OGA,GABBR1,GALNT15,INPP5K,CPLX2,ALDH1L1,FREM1,PCDH17,PPARGC1A,MALT1,LYVE1,SPIN1,AIFM3,HTATSF1,GPD1,CCDC184,PCLO,CNTRL,GRB10,DIDO1,PLCD4,SERP2,PSIP1,FAM107A,SLC2A6,NXPH3,BACH2,HLF,HNMT,CPT1C,DHX35,CELF5,ICA1,IFI16,ITGA7,KIT,PAXBP1,MAT2A,EFHB,SHC3,KITLG,BLOC1S2,ADAM22,MSR1,NRBP2,THYN1,NRCAM,SETD4,P2RX7,PDE4A,PFKFB2,PFKFB3,ZFYVE21,ANKRD16,PMP22,LRP12,PSAT1,PILRA,PPARA,TATDN3,PRKCB,MAPK10,SLC26A11,GRAMD1C,DIRAS2,PRODH,LAMA1,MTMR10,PTN,PTPRB,PTPRG,TUG1,MARCH1,PID1,IQSEC3,RBBP6,MORC4,RGS3,RGS12,CCDC82,MEG3,HUNK,NCBP3,FAM102A,SHC4,HKDC1,DZIP1,SLC8A1,ARHGEF40,ZKSCAN3,SPATA7,GLT8D1,IZUMO4,SPTAN1,RBM26,CLSTN2,MESP1,SEPT3,NECAB1,SYNE2,PLCB1,COBL,ANKRD12,IQCE,TRIM2,TCF12,SZT2,PCDHGA9,SYNE1,NSD1,PCDHAC2,GPRIN3,SLC35G2,DNAH7,CHST8,ZMAT3,RASD2,ZNF346,CA14,TUBB2A,RPRM,PDIA2,CLDND1,ATP6V0E2,CRB2,ZBTB38,REEP1,ZSCAN26,STOX2,SIGLEC10,RGS7BP,DNAH10,FAM13C,GJC2,TTC7A,AAAS,CPNE4" Drug ctd:C009277 sodium arsenate CTD 9.36E-09 4.10E-04 2.17E-06 2.45E-05 270 1719 "RALGAPA1,CLK4,ACTN1,METAP1D,FMNL2,KLHL32,MTUS1,AGT,TAOK1,SPARCL1,ALCAM,AMT,OGT,LRCH2,SEMA7A,APC,USP37,CHID1,SLC4A4,ATP2A2,MYOM1,BACH1,BCHE,NRP2,CFLAR,DST,FUBP1,MTMR2,SGCE,CACNA2D1,PTBP2,CAMK2G,CARS,SPAG9,NFS1,KYAT1,LDB2,KRIT1,USP2,CDC25B,CDH2,ZMYM4,MAGI1,CDO1,CLGN,CFL2,SRSF11,B4GALT6,CLCN3,ABCG2,QKI,HECTD1,CNTFR,AKAP6,COL11A2,RCHY1,BAG4,IGDCC3,CPS1,CLOCK,RBM39,RNF14,ANKRD44,NCOR1,CST3,APPL1,UBXN2A,USP6NL,TBC1D5,MATR3,ZC3H11A,SACS,SPOCK3,CHRDL1,DMD,DMPK,NR1D2,CPEB2,SLC12A6,PDCD6IP,DTNA,ABCC5,GOLT1B,TSPAN5,HIPK3,FCF1,TMTC1,PHF20L1,EGFR,AASS,EIF5,PLEKHA1,ING4,PAN3,DCTN4,HSD17B14,EPB41,LRRC17,MRVI1,REEP2,ACSL4,FKTN,PRMT5,KAT8,FGFR1,AFF2,FOLR2,NBEA,ZBED3,TRIM16,TPK1,ATP6V1H,OGA,ERAP1,GATM,GCK,GFER,PPARGC1A,MALT1,BRD8,GLUL,FERMT2,PRUNE2,GPER1,RNF165,BVES,FAM107A,GUCY1A1,HAS2,MAN1B1,HMGCR,HNF4G,AGFG1,HSF2,SMAP1,IGF1,IL6ST,FAM69A,ITPKB,KCNB1,KLHL23,KIF5A,KIT,STXBP5,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,LSAMP,LSS,MAP2,MAPT,MAT2A,MBNL1,MBP,CHIC1,MEF2C,MKLN1,MN1,MYCN,NFE2L2,NFIX,NNAT,TREM2,ETFRF1,PDE4B,PFKFB3,OLA1,PGAM2,PIK3C2A,PIK3R1,CCSER2,SNX10,XRN1,PLTP,PSAT1,SCHIP1,MINDY2,PRKCB,MAPK3,MAPK9,PRPH,PRPSAP2,GDPD1,ANKHD1,PTPRB,USP47,FAT4,RBBP6,RDX,REV3L,MRPS18A,SLC25A36,SETD5,SARS,SEMA6D,ATXN2,SCN7A,FNIP1,SMPD3,HSPA4L,SGK1,KIF21A,CHD9,DZIP1,PREX2,PPP4R3A,CCDC88A,BTBD7,CPEB4,ZKSCAN3,RCOR3,KIF13A,TMCC1,FAM126B,PDZRN3,RBM34,FNBP1,MYCBP2,ZNF423,NFASC,TROVE2,ITPRID2,LARP4,SS18,ERBIN,ADHFE1,ARC,SYPL1,TACC1,MGRN1,TCF4,SIN3B,DMXL2,ZEB1,TRIM2,TCF12,NSD1,FRYL,AP4E1,AKTIP,PIK3R5,TP53BP1,TPM1,TPM2,NR2C2,SYNPO2,TRIO,TRPS1,DCBLD1,TSN,RPL7L1,PDIA2,RICTOR,ZNF24,SLC38A1,EVI5,ADAMTS9,CIAPIN1,MDH1B,WNK2,RGS7BP,AMN1,DOCK8,ST7,RTN4,ACTR3B,JMJD1C,MSRB3" Drug ctd:C038091 butylparaben CTD 1.01E-08 4.43E-04 2.33E-06 2.63E-05 44 158 "ACTN1,UNC5A,CASK,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CAMK2B,CACNA2D2,CHRDL1,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,FGFR1,FYN,GPER1,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,NXPH3,NF1,NRCAM,NTRK2,NTRK3,CNTN3,PLIN1,MAPK3,RELN,ROBO1,STX1B,HES6,NLGN1,SPP1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug 2082_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "ASIC1,ADD1,AMPD3,AMT,CDC14B,CDK10,NUMB,KYAT1,CCNT1,CNOT8,BAG4,SH2B1,HINFP,VCAN,PDE4DIP,ARHGAP32,DBT,SCML2,BAIAP2,TRAF3IP2,ERAP1,DISC1,INPP5K,TXNL4A,COPS8,DIDO1,ICA1,INPP5B,JAK2,LIG4,MAP4,MBNL1,PIK3R1,NLE1,SLC25A23,FA2H,ZSCAN32,SH3BGR,SH3BP2,ASAP3,BTBD7,SPATA7,ARHGAP26,JMJD6,TRIM2,TNS2,ZMAT3,TSN,XRCC4,MAP3K12,EPM2A" Drug 5394_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "ADRA1D,SEMA6A,LTBP4,APOC1,RASL11B,ATP2B2,SLC2A11,ST3GAL5,CACNA1I,CACNA1G,CFAP410,CAMK2B,CAMK2G,CBFA2T2,PCYT1B,COL9A3,CSF1,ARHGEF4,VPS13B,DLL3,FYB1,PCLO,GSTM5,C2orf72,LIG4,SMAD1,MID1,AFF1,MSR1,NNAT,NOVA2,PFKFB2,MAPK7,C1orf54,ZFHX4,RPS6KA2,CPEB3,ABLIM3,SMARCD3,ZHX3,NMNAT2,ZNF423,SAMSN1,RGL1,TACR1,IQCE,ZEB1,DOCK9,LAT2,SPHK2,KCNAB1" Drug 5583_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "ADRA1B,AMPD3,APC,ATP2A2,CFAP410,CAMK2B,CHN2,CNTN1,CSF1R,PDE4DIP,RIMS2,DUSP9,ING4,VPS13B,NRN1,ZNF589,FGF13,FGFR3,FHL1,AFF2,PDLIM5,GAD1,SIGLEC8,PCDH17,GLYR1,GPR37,KCNN2,ADAM22,MSR1,MYO7A,NNAT,PDPK1,PLTP,LRP12,LRRN3,CEP41,ZMAT4,KCTD17,ATP10B,SAMSN1,RGL1,PLCB1,MCF2L,DMXL2,TRIM2,SZT2,CRTC1,HEY1,PDIA2,SLC30A3,KCNAB1" Drug 5747_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "TRMT9B,PRX,SLC2A11,N4BP2L1,CACNA1I,HAP1,CACNA2D2,CHRNA4,ABCG2,COL9A3,CSF1R,PHF14,ARHGAP24,EDN1,EDN3,PLXNC1,ELN,ZNF549,CDKL3,OLFM1,ZNF44,SYT17,INPP5K,POLL,PRUNE2,PADI2,ICA1,SCIN,KCNJ5,LSS,MATN3,LYRM9,NTRK2,POLG,POU6F1,MINDY2,PPP2R2B,DCHS2,ACSS3,ZCWPW1,RNASEL,NEK11,FRMPD1,ST6GAL1,PKNOX2,SLC9A5,KIF13A,IQSEC2,ATP10B,OBSL1,GAN" Drug 3800_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "ADD2,GAS7,LGR5,ARHGDIG,ATP6V0A1,RGS9,CACNA1G,KALRN,USP2,LY86,ABCG1,RGS6,ARHGEF10,RIPOR2,INTS1,DMPK,DNAH9,AFF2,FOLR2,PRELID3A,GFER,GRM8,IRAK3,ATXN2L,HLF,VSIG4,ICA1,KITLG,MMP16,MYT1,NDP,NRCAM,NTRK2,NTRK3,P2RX7,PCDH9,GPR85,PPARA,PPP2R2B,GDPD2,ZMAT4,RGS12,CCDC102B,SALL1,CNKSR2,PKNOX2,PCDHA3,HIF3A,UCHL1,LAT2,SEMA3B" Drug 4631_DN Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "PDE8B,ATP2B2,ALDH7A1,ADGRB2,BAIAP3,CACNA1A,CBFA2T2,SCARB1,LARGE1,CNOT8,AKAP7,CREM,MFAP3L,DTNB,HEYL,MTSS1L,SPEG,ZNF44,SIGLEC8,GCNT2,CACFD1,SOX21,ICA1,FAM69A,KCNF1,LIG4,MAPT,NF1,PPARA,PTPRB,TMEM231,KHDRBS2,FBXW7,SBF1,SH3BP2,FRMPD1,SLA,FAM214B,SLC14A1,RBM34,TSNAXIP1,DIP2A,ADGRL3,IQCE,CRTC1,THRA,TIMP4,TK2,TNS1,XRCC4,SPHK2" Drug 3777_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-08 4.66E-04 2.37E-06 2.67E-05 51 197 "CDK10,MARCH3,ADAM23,C5,ARHGEF1,SCARB1,NRXN3,HAPLN1,PDE4DIP,DAPK3,ARMCX2,MFAP3L,PLPPR4,TOM1,PLXNC1,TUBD1,CDKL3,ETV1,EFCAB2,PRELID3A,OGA,DISC1,INPP5K,GCNT2,GFER,TDRKH,NELL2,NF1,P2RY1,PRKAR1B,SNRK,ACSS3,ROGDI,TCP11L1,SH3BP2,ASAP3,DZIP1,SLC4A3,ARHGEF40,THSD1,PHLDB1,ARHGEF9,TCF4,DNAH7,TIAM1,CDK20,SSBP2,SPHK2,SEMA3B,EPM2A,PHTF2" Drug 2977_UP (-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-08 4.81E-04 2.43E-06 2.74E-05 43 153 "MTUS1,BIN1,GAS7,DNAH17,NCOA1,CFLAR,SLC16A4,CD86,CD38,CHN2,CLOCK,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,GPRASP1,FAM13A,ING4,PRKAG2,TRAF3IP2,GALC,MEF2C,PDE4B,PDE4D,SERPINI1,SMOX,QDPR,TMEM255A,SEC14L1,SGK1,FAM214B,ARHGEF40,SPTAN1,PLCB1,PDLIM2,TCF4,SLC44A1,TLR4,FLRT2,CLDND1,ZBTB38,NLRP3" Drug 2572_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-08 5.25E-04 2.64E-06 2.97E-05 50 192 "MTUS1,EPB41L5,BMP7,HIP1R,SLC16A4,CD86,CD38,CLGN,CREM,CRMP1,SIPA1L1,PDE4DIP,SLITRK5,PPP1R16B,DOCK4,MFAP3L,TMCC2,ING4,COQ7,EPHB1,F5,FGFR3,FYB1,PADI2,TJAP1,MEF2C,ZNF862,PDE4B,PLCD1,PLEC,MAPK10,PTK2,PTPRB,PTPRN2,RXRA,TRAPPC13,ZNF821,SLC2A5,FAM214B,ARHGEF40,SPTAN1,LHPP,ATP10B,SEPT8,ARHGEF9,CUX2,SZT2,TPM1,FLRT2,LAT2" Drug 2964_DN Tridihexethyl chloride; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "AP2A2,MTUS1,CDC42BPA,APC,ADAM23,BCL7A,SYNJ2,SCAPER,CFAP410,CAST,ARHGEF1,CLGN,SOCS6,HOMER3,PDE4DIP,SLITRK5,PPP6R2,ZFYVE16,SPATA2,RUSC2,DTNA,CD320,F8,FHL1,POMT1,CAMKK2,ERAP1,SRCAP,ADAM28,MAP4,SCAMP5,MX1,NEK1,NF1,OGG1,PDE4A,ENPP2,NLE1,PTPRN2,CEP97,ZCWPW1,ANKRD6,ARFGAP1,KDM4B,IZUMO4,ARHGEF9,PJA1,TNS1,PLPPR2,EVI5,MARCH8" Drug 6627_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "ALK,TRMT9B,KCNAB2,ATP1A3,ADAM23,GYG2,BAIAP3,CNTFR,CSF1,PDE4DIP,DTNA,EDIL3,EDNRA,AASS,MTSS1L,EZH1,FGF1,FGFR1,FLT1,GALC,ERAP1,ZNF276,GLI2,GNAL,GNAO1,LPAR4,GPER1,SPACA9,IRAK3,ELOVL5,KCNB1,KCNN1,MAPT,TM6SF1,NF1,NNAT,NOVA1,PIK3R1,PLXNB1,PPP2R2B,EMID1,SEMA6D,SCN2B,FRMPD1,ASAP3,TACR1,SLC44A1,TPM1,RUNDC3B,VIPR2,JPH3" Drug 2234_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "SYN3,ASIC1,AP2A2,NME5,ALCAM,AMPD3,BIN1,CDC42BPA,APOC1,N4BP2L1,SYNJ1,SCAPER,SEPT7,RAB33A,SULT4A1,BAG4,SNCAIP,CSF1,RIPOR2,HDAC4,TBC1D5,EDN1,HIPK3,HEYL,FHL1,PRELID3A,OGA,GPER1,SOX21,SMAD1,MGAT3,PLCD1,C19orf57,PPARA,PPP2R2B,CEP41,GRAMD1C,RELN,KCTD17,SALL1,ZNF821,SH3BP2,PKNOX2,TBCEL,TCF4,TEK,AP4E1,THRA,ICAM5,TNS1,TPM2" Drug 4980_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "ASIC1,AP2A2,AGT,NME5,BIN1,FAM131A,ARRB1,SLC2A11,LDLRAD4,CAMK2G,CBFA2T2,ARHGAP33,CHN2,HOMER3,CSF1R,SEC14L5,DMPK,RASGRP2,ERCC2,FGFR1,FHL1,SCARA3,OGA,GRM8,ICA1,KCNJ5,KIT,MAP2,MEF2C,NELL2,NNAT,RETREG1,CEP41,MAPK7,ZSCAN32,KCNIP1,FAM214B,KDM4B,RGL1,PHLDB1,OBSL1,CRTC1,DNAH7,PARD3,TRIO,FLRT2,WIPF1,ZBTB14,NDRG4,MKRN3,SEMA3B" Drug 3336_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "NDRG2,ALK,APAF1,ARNTL,CDK13,KSR1,BAIAP3,CFAP410,ARHGEF6,PICK1,AKAP6,SPOCK2,HIPK3,EPHB1,ERCC2,ZNF589,AGAP2,PDLIM5,GNAO1,GPD2,ITGAM,AFF1,MSR1,MYCN,NEK1,OPRL1,P2RY1,PDE4A,PFKFB4,STRN3,LRP12,PTPRO,TMEM255A,GAL3ST4,KCNIP1,SALL1,SEMA6D,ASAP3,COA1,LIMCH1,PDZD2,TSNAXIP1,HECW1,UNC5B,ARHGAP26,JMJD6,OBSL1,DNAH7,TNS1,VSNL1,SPHK2" Drug 4081_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "AMPD3,APC,KIF1A,CACNA1I,RAB28,CLCN3,RAB26,NRG2,CRMP1,NCOR2,ARHGEF10,VCAN,PDE4DIP,BRINP1,MFAP3L,RUSC2,SPOCK3,CDON,CELSR3,EIF4G2,COQ7,MTSS1L,ZNF549,DLC1,ST3GAL6,SCARA3,SEMA4D,SEPT9,LPAR4,MGAT3,NOVA1,NOVA2,SAMD9,ZSCAN2,RXRA,FNDC3A,NLGN1,PPP4R3A,BTBD7,ZNF415,RBM34,IQSEC2,LHPP,PCDHGA10,PCDHA5,TIAM1,CABIN1,OSBP2,WIPF1,XRCC4,TIGD6" Drug 6033_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "BIN1,PPFIA4,APLP1,PLA2G4C,CDK13,SLC4A4,ADAM23,TAOK2,SULT4A1,WHRN,NRG2,ARHGEF10,CNTNAP2,DOCK4,DGKG,RUSC2,DMPK,DTNB,RCAN2,RASGRP2,ZNF589,HPCAL4,NSG1,FYB1,GCNT2,GPD1,C2orf72,MAP4,MEF2C,TAGLN3,NOVA2,NTRK3,GPR85,SAMD9,PTX3,ZNF493,RGS4,RGS12,PNMA8A,SCN8A,RASA3,SNCA,HECW1,TBCEL,CUX2,TNS1,TRPM2,VIPR2,LAT2,MKRN3,SPHK2" Drug 6036_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-08 5.60E-04 2.70E-06 3.05E-05 51 198 "SYN3,ACHE,AGT,C1QTNF1,APOC1,ALDH7A1,BAIAP3,LDLRAD4,P2RX6,ASIC3,SULT4A1,CNR1,SNPH,BRINP1,SPOCK3,CDON,F5,FHL1,AGAP2,AFF2,GCNT2,MSL3,GNAO1,LPAR4,STMN2,GRM8,GUCY1A1,HAS2,HLF,TJAP1,KCNJ5,LAMA2,AFDN,NELL2,GPR85,SEPT4,SAMD9,PTPRB,PTX3,SUGCT,ZFP2,SNCA,IZUMO4,WSCD1,FAM189A1,PCDHA5,SLC35G2,CHST5,FLRT2,ZNF711,KCNAB1" Drug 6709_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.35E-08 5.89E-04 2.83E-06 3.19E-05 49 187 "ADRB2,CDC14B,ARNTL,MARCH3,ST3GAL5,SCAPER,USP2,CHN2,ABCG1,PDE4DIP,CTH,JAKMIP2,MFAP3L,C2CD2L,PLPPR4,FAM13A,RGS17,RASGRP2,TAOK3,NBEA,FYN,CYP46A1,PCDH17,STON1,ICA1,FAM69A,INPP5B,LIFR,MXI1,PCDH9,ENPP2,SERPINI1,RETREG1,ENOX1,RGS4,RPS6KA2,SH3GL3,FRMPD1,KDM4B,ELOVL4,CEP68,RGL1,SYT1,COBL,TAL1,SSBP2,TRIM9,SLC17A7,GAN" Drug 4846_DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.44E-08 6.31E-04 3.02E-06 3.40E-05 50 193 "ABHD6,AK2,ARNTL,ARRB2,NUMB,MPDZ,SCAPER,MTMR2,CA12,CAMK2G,KYAT1,KRIT1,AKAP7,DCAF8,KIAA0586,DMPK,RCAN1,EIF5,ENO2,EPB41L2,AMOTL2,FAM49B,INPP5K,SRCAP,SLC2A6,INPP5B,KCNH2,MMP16,RETREG1,PLEC,PPP2R2B,PPP5C,PRPH,PTK2,SH3BP2,FAM214B,ELMO2,TTC17,FNBP1,TEX2,TTBK2,TACC1,IQCE,SLC44A1,TK2,KAT6B,UBE3A,NDRG4,KAT6A,PHTF2" Drug 7494_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "ADRB2,APAF1,APC,STX16,KYAT1,CHRNA4,HOMER3,NRG2,CSF1,VCAN,BRINP1,RUSC2,RCAN1,DTNA,CELSR3,EGFR,MBNL2,TENM1,ING4,RGS17,HSD17B14,ANKMY1,ACSL4,FGFR1,ANKFY1,PDLIM5,ICA1,KCNN1,MIA2,MX1,NEK1,PFKFB2,MAPK7,PTN,ZSCAN2,PID1,SH3TC2,RGS4,SH3BP2,BTBD7,ZNF667,KDM4C,SMG6,TCF4,TRIM2,TNS2,SLC35G2,BEX4,FAM155A,EPM2A,PHTF2" Drug 4634_DN S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "TRMT9B,AMH,AMPD3,AMT,PPFIA4,SEMA4G,PDE8B,ATP2B2,CACNA1I,CFAP410,SYNGR3,LARGE1,B4GALT6,ABCG2,HOMER3,AKAP7,WHRN,CABP1,SLC4A8,NCOR2,DTNB,FCF1,MBNL2,MTSS1L,NRN1,ST3GAL6,FGFR3,AFF2,ZNF44,TRAF3IP2,SIGLEC8,MSL3,CACFD1,ICA1,KCNF1,NDP,NNAT,PRKAR1B,MAPK7,SAMD9,RIPOR1,ZNF821,ASAP3,COA1,ST5,METTL3,OSBP2,XRCC4,ZNF711,NT5M,EVI5" Drug 5790_UP Tropine [120-29-6]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "ASIC1,APAF1,APOC1,ARRB2,ATP1A3,SLC4A4,ATP2A2,NRP2,KSR1,BAIAP3,FOXN3,AKAP5,CSF1,ARHGEF10,RIPOR2,ARMCX2,DTNA,EDIL3,ING4,TNK2,APC2,ETV1,REEP2,SEMA4D,ERAP1,DISC1,HPGDS,GPER1,SPACA9,PADI2,KCNN2,KHK,KPNA5,LMO2,MAPT,MGAT3,ADAM22,TAGLN3,PLCD1,VPS13C,RGS4,DZIP1,OGDHL,ZHX3,SP4,ARHGAP26,COBL,SYT5,ZEB1,ZNF711,ACTR3B" Drug 3845_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "ABHD6,AP2A2,NME5,AMH,CDC42BPA,APC,CDK13,MARK4,GYG2,SGCE,C5,CALB2,CSF1,RIMS2,ZNF804A,MFAP3L,DMPK,EDNRA,ELN,HSD17B14,ZNF589,FYN,SYT17,GFER,TDRKH,STON1,GRIK5,SLC2A6,HNMT,INPP1,MIA2,MPP2,MYO7A,NPR2,RETREG1,SLC25A23,POLG,PRPH,SNRK,TMEM104,ZSCAN2,EPN2,FAM214B,ARHGEF9,MCF2L,CRTC1,TNS1,PLPPR2,VIPR2,LMF1,KCNK12" Drug 3809_UP Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "ADD2,SPARCL1,LTBP4,TRMT9B,APAF1,GAS7,ADGRB2,RGN,ABCG2,NRG2,ERC2,BRINP1,DTNB,VPS13B,EZH1,REEP2,ABCA8,SEMA4D,FLT1,NSG1,ALDH1L1,POLL,LILRA2,ADAMTS6,PADI2,KCNB1,MATK,MGAT3,MYT1,NOVA2,NTRK2,P2RY1,PDE4A,GPR85,POU6F1,PRKAR1B,PTCH1,ZMAT4,RGS12,SH3BP2,CNKSR2,SLC2A5,SLC14A1,IQSEC2,VPS13A,TK2,CHST5,HIRA,OSBP2,SLC30A4,SLC17A7" Drug 5787_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.53E-08 6.70E-04 3.12E-06 3.51E-05 51 199 "CDC42BPA,MARCH3,SYNJ2,C5,ARHGEF2,SRSF11,SOCS6,RAB28,CPS1,CSF1R,GIT2,C2CD2L,FEM1B,IRAK4,TNK2,SPEG,BAIAP2,B4GALNT1,SRCAP,PCDH17,RAB40B,GNG4,TJAP1,MAP4,MATN3,TM6SF1,SCAMP5,ZNF862,NACA,PPP5C,CSRNP3,ZNF821,ASAP3,FBXO11,ST6GAL1,FAM214B,CCDC88A,BTBD7,KDM4C,SPTAN1,LHPP,THSD1,ELOVL4,SUPT5H,SYT1,COBL,WSCD1,CHST8,ZBTB14,HPS4,UBE3B" Drug 4237_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.54E-08 6.75E-04 3.12E-06 3.52E-05 46 171 "ADRB2,NME5,EPB41L5,ARNTL,MARCH3,MARK4,ST3GAL5,HAP1,HIP1R,ABCG1,PDE4DIP,CNTNAP2,CTH,PLPPR4,RGS17,TBC1D16,PTK2B,BAIAP2,NBEA,FYN,CYP46A1,PCDH17,STON1,GUCY1B1,BACH2,FAM69A,ITGA7,MAP2,MMP16,TAGLN3,PCDH9,SERPINI1,PRPH,ENOX1,RGS4,SH3GL3,WDR47,THSD1,ELOVL4,RGL1,SYT1,COBL,RUNDC3B,SSBP2,TRIM9,PLSCR4" Drug 6741_UP Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-08 7.58E-04 3.48E-06 3.92E-05 50 194 "ADCY6,ADRA1B,GAS7,BCAS1,PPP4R4,DLGAP1,HOMER3,RIPOR2,SPOCK2,MFAP3L,SV2B,EDIL3,HIPK3,COQ7,ETV1,CORO2B,DLC1,FER,FGF1,TRMO,SYT17,PRUNE2,ELOVL5,KIT,ADAM22,MX1,NF1,PCBP3,PALM,PDE4A,PDE4D,PPP2R2B,CCDC40,RFX2,RGS12,KCTD17,TCP11L1,SOX3,ZHX3,TAL1,TCF4,SZT2,HIF3A,GPR161,HIRA,TUBB1,UBE3A,LAT2,EMSY,PARP11" Drug 4125_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.73E-08 7.58E-04 3.48E-06 3.92E-05 50 194 "ASPHD1,NDRG2,ADD2,ALCAM,AMPD3,GAS7,CDC14B,PPP4R4,CACNA1I,CD86,CDO1,SULT4A1,ARHGEF6,CRY2,SNCAIP,DAPK3,SPOCK2,ARMCX2,PLXNC1,LRRC17,PTK2B,FGFR3,SIGLEC8,ATXN2L,ICA1,KCNJ5,KCNN1,SMAD1,MAP2,MAPT,AFDN,MN1,ADAM22,MX1,NEFM,NNAT,NOVA1,GPR85,CEP41,PRKAR1B,ZSCAN2,SALL1,SH3BP2,LIMCH1,KIF13A,ATP10B,KIAA1107,WNT7A,SLC17A7,HRASLS" Drug 5683_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-08 8.02E-04 3.63E-06 4.09E-05 51 200 "NDRG2,AP2A2,C1QTNF3,DOC2A,APBA2,SGCE,CACNA1I,KALRN,HAP1,FOXN3,CHRNA4,LY86,WHRN,CRHBP,SUSD5,IPCEF1,CNTNAP2,ARHGEF4,RIMS2,EGFR,MRNIP,NRN1,FYB1,SRCAP,GNAL,GPER1,SOX21,C2orf72,KCNH2,ADAM11,NTRK3,PCDH9,ENPP2,PLCL1,SEPT4,MINDY2,PRKCB,ZNF493,TRIM68,KCTD17,CCDC102B,HKDC1,SNCA,SYT5,DOCK9,HIF3A,TIMP4,CLIP2,SPHK2,ADAMTS9,SEMA3B" Drug 4005_DN Suprofen [40828-46-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-08 8.02E-04 3.63E-06 4.09E-05 51 200 "ASIC1,ADRA1D,C1QTNF1,GAS7,LGR5,CDK10,DNAH17,C5,RAB28,WHRN,COL9A3,SH2B1,EDNRA,MBNL2,MTSS1L,ETV1,SEMA4D,DLL3,ZNF44,TRAF3IP2,TMEM8B,DISC1,POLL,GRM8,ICA1,SHISAL1,MN1,NFYA,CNOT4,PRPH,SAMD9,ZCWPW1,SUGCT,KIRREL1,ZNF821,ZFP30,PPP4R3A,ZNF667,SMARCD3,TSNAXIP1,IQSEC2,DDN,TCF4,SYNE1,TIAM1,TK2,CABIN1,RPRM,LMF1,SEMA3B,KCNAB1" Drug 2633_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-08 8.02E-04 3.63E-06 4.09E-05 51 200 "ASIC1,AP2A2,AGT,NME5,APBA2,APLP1,APOC1,MARK4,SLC4A4,AZGP1,ADGRB1,CACNA1I,CA4,ARHGEF1,TAOK2,NRG2,ARHGEF10,PDE4DIP,MFAP3L,DMPK,HS3ST2,HEYL,FRY,EIF4G2,HSD17B14,PIPOX,ZNF589,FGFR1,GAD1,CPLX2,RAB30,GPR75,TDRKH,STON1,GRM8,INPP5B,MAPT,KITLG,MSR1,NOVA2,C19orf57,SH3BP2,SMARCD3,SPTAN1,TK2,VSNL1,ZFP37,ZNF154,ADAMTS9,SMIM8,TIGD6" Drug 5675_UP Colchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.95E-08 8.54E-04 3.85E-06 4.34E-05 49 189 "LTBP4,AMPD3,CDC14B,CACNA1I,WHRN,CRYM,AATK,CSF1,CSNK1E,MAML1,BRINP1,GIT2,SHANK1,DTNA,EDN1,EGFR,ENO2,ERBB4,REEP2,HPCAL4,FYB1,GAD1,SRCAP,RAB30,PCLO,GRM8,GSN,ATXN2L,SHISAL1,INPP5B,MBP,PFKFB2,NLE1,STRN3,POU6F1,PTPRE,PTPRN,TCP11L1,EPN2,OGDHL,MAPKBP1,JMJD6,SYP,ADGRL3,CHST5,ADAMTS9,SLC17A7,PLSCR4,HRASLS" Drug 4388_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.04E-08 8.92E-04 4.00E-06 4.51E-05 47 178 "KIAA1324,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,WHRN,AKAP12,CRYM,PDE4DIP,ARMCX2,TMCC2,TSPAN5,FAM13A,RASGRP2,STX2,HPCAL4,FYN,CYP46A1,STON1,MAP2,MPP2,PDE4A,SERPINI1,PRPH,GAL3ST4,RPS6KA2,SATB1,SH3GL3,ASAP3,WDR47,FAM214B,PKNOX2,SLC6A8,ARHGEF40,LIMCH1,NMNAT2,ARHGAP26,ELOVL4,RGL1,STXBP1,HEY1,RUNDC3B,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug 1012_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.07E-08 9.08E-04 4.00E-06 4.51E-05 50 195 "ASIC1,AK2,AMT,APOC1,MARCH3,CFLAR,CA4,KYAT1,KRIT1,FAM189A2,SMARCAL1,LRIG1,CTH,JAKMIP2,LYPD1,DMPK,CNNM1,IRAK4,ZNF589,FGFR1,COPS8,GPER1,GRB10,MUM1,ICA1,IGF1,KHK,MAPT,MIA2,MPP2,ADAM22,LYRM9,CDK18,SLC25A23,PPP2R2B,PPP5C,RIPOR1,FAM184A,RPS6KA2,ZNF821,ZFP30,ZSWIM8,ARHGAP26,TRIM2,ZNF34,CABIN1,VAV1,WIPF1,FTSJ1,MAP3K12" Drug 4232_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.07E-08 9.08E-04 4.00E-06 4.51E-05 50 195 "ASIC1,NME5,SEMA6A,GAS7,CDK13,ATP2B2,SLC2A11,BMP7,IL33,NRXN3,CABP1,HAPLN1,PDE4DIP,RIMS2,BRINP1,DBT,ZNF391,FGF1,ERGIC3,SYT17,TDRKH,CACFD1,GRM8,AP4S1,ATXN2L,ICA1,IL6ST,KIF2A,LSS,ADAM11,NEFM,PDE4D,RET,KLHDC8A,PNMA8A,SCN2B,ZNF334,CDK19,PHLDB1,SYT1,ADGRL3,TBL1X,KLHL4,SZT2,ZNF34,TNS1,CDK20,KCNK12,KCNAB1,JPH3" Drug 6999_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.07E-08 9.08E-04 4.00E-06 4.51E-05 50 195 "ASPHD1,ABHD6,NDRG3,NCOA1,BMP7,SCAPER,GYG2,SYNGR3,LHX2,NECTIN3,CRY2,ABCG1,ARHGEF10,DBN1,SGSM2,SEZ6L2,MBNL2,EGR3,ENO2,RASGRP2,FECH,FHL1,GAD1,POLL,RASSF8,ITPKB,MAP4,MAPT,MBD1,MGAT3,MPP2,RETREG1,MTRF1L,FA2H,PRPH,PTCH1,FBXW7,EMID1,ZNF821,FRMPD1,ARHGAP26,ELOVL4,STXBP1,COBL,MTCL1,MCF2L,TMEM121,TIAM1,TPM1,PLPPR2" Drug 4016_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.07E-08 9.08E-04 4.00E-06 4.51E-05 50 195 "RALGAPA1,AP2A2,ALK,ANK2,PPP4R4,RASL11B,SLC4A4,NRP2,CFLAR,SYNJ1,LDB2,TPP1,HOMER3,AKAP5,ENTPD4,CNTNAP2,EDIL3,EDNRA,HIPK3,FCF1,CELSR3,ING4,ERBB4,ETV1,NRN1,ZNF589,NEU3,STON1,ELOVL5,ITGA7,KCNN1,CNOT4,SETD4,LRRN3,BEND5,STK32B,CPEB3,DZIP1,SLC4A3,OGDHL,ZBTB43,EXOC7,TMPO,R3HDM1,CDK20,TRIO,VGF,ZNF225,PHTF2,DPF3" Drug ctd:C029297 vinylidene chloride CTD 2.11E-08 9.24E-04 4.05E-06 4.57E-05 237 1485 "KCNH8,SYN3,NDRG2,RNF157,ADD2,HECW2,OSBPL1A,OSBPL6,ADGRF5,CEP126,CDC42BPA,ANK2,APAF1,APOC1,APOC2,AQP6,IGDCC4,ARRB2,ASPA,NCOA1,ATP2B2,ATP6V0A1,BCL7A,CFLAR,PROM1,BMPR1B,ST3GAL5,SYNJ2,CA4,CA8,CACNB4,CALB1,PRC1,CLDN10,LDB2,ENTPD2,CDC25B,LRRFIP1,LARGE1,CDO1,FOXN3,PLEKHB1,MS4A7,CHRNA4,SLIT2,NGEF,FBXO7,MAP4K4,LY86,CNTN1,GAL3ST1,SLC35F1,AKAP12,GDA,CSF1,LRIG1,IPCEF1,SIPA1L1,PPP1R16B,ERC2,UBXN2A,CTH,CYBB,TCAF1,DGKG,DBT,MFAP3L,SACS,DUSP9,EBF1,SNX29,RASGRP1,TMTC1,FRY,OPTN,AASS,ENO2,RCAN2,GPHN,DENND4A,IGSF6,ETV1,SH3YL1,TUBA1B,TAOK3,DLC1,FCGR1A,CHST15,FCGRT,FGF1,FGFR1,FLT1,NOP56,NBEA,SMC2,HVCN1,FAM49B,TPK1,CELF1,FUT9,FYB1,DENND2A,GALC,MTHFD2,SYT17,ACSS1,GATM,ALDH1L1,FREM1,GHR,PPARGC1A,HPGDS,DBF4,GLUL,AIFM3,RAB40B,LNX1,ADGRA3,GPR34,PCLO,TPPP,FAM107A,HBA1,BACH2,HLF,HMGCL,HP,AGFG1,IGF1,INPP5B,ITGAM,KCNJ16,KHK,L1CAM,LIFR,SFXN5,MAP2,MAP4,MARK1,AQP11,MEIS2,MGAT3,KITLG,MN1,MYO7A,ALDH1L2,NFIX,VWA2,NPR2,P2RX7,TREM2,PDE4D,PFKFB3,PFKFB4,PGAM2,SNX10,PLCL1,PLEC,SMOX,PLXNB1,SEPT4,EPB41L4B,IRX1,PPARA,PPP1R1A,PPP2R2B,RANBP3L,PRKCB,GDPD1,MASP1,PTH1R,ELOVL2,SPDL1,PTPN13,PTPRB,PTPRE,PTPRO,QDPR,OXR1,RASGRF2,BEND5,RGS4,NUDT11,ZFHX4,RNH1,LGI2,SUGCT,STK32B,LRRK2,PTGR2,SCP2,RASA3,SH3BP2,SHMT2,ST8SIA1,ANKRD6,NUBPL,SLA,SLC8A1,SLC11A1,SLC12A4,SLC22A4,LIMCH1,UNC5B,IQSEC2,DDN,PBLD,APOM,SEPT8,RGL1,ADHFE1,KANK1,SULF2,MTCL1,MCF2L,TBCEL,NSD1,TEK,ZMAT3,TMPO,BEX4,TNS1,TP53BP2,AMACR,PPIL6,CA14,P2RY12,NPDC1,SEMA3B,NAV3,PLD4,FAM13C,DOCK8,PHTF2,FBXO36,ZDHHC20,CPNE4" Drug 2721_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.34E-08 1.03E-03 4.48E-06 5.05E-05 49 190 "NDRG2,ADD2,ALK,BEGAIN,AMPH,BIN1,APBB2,MARK4,SGCE,CACNA2D1,CDO1,CHN2,TAOK2,LHX2,RAB26,CABP1,ABCG1,GSDME,MAMLD1,FAM13A,RASGRP2,ETV1,TBC1D16,SIGLEC8,INPP5K,ADAM28,KCNMB4,STON1,PCLO,IFI16,FAM69A,ITGA7,MEF2C,SERPINI1,PLCD1,PMP22,MAPK7,CNNM2,TMEM255A,SNCA,HECW1,RGL1,STXBP1,DNMBP,TPM1,SSBP2,KLC2,REEP1,PRDM10" Drug 4508_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "SYN3,C1QTNF3,LTBP4,AMPD3,SEMA7A,CDK13,NRP2,ST3GAL5,CA8,RUNX1T1,NRXN3,STOML1,COL9A3,CSF1,PDE4DIP,ARHGEF4,MAML1,MFAP3L,DMPK,NCALD,FAM49B,IQGAP2,CNTRL,ICA1,IFI16,ITGA7,KCNH2,MMP16,MX1,FXYD7,NPTX2,GPR85,SAMD9,FBXW7,TCP11L1,SEMA6D,ZNF821,STUM,FRMPD1,RBM34,DOK5,SOX15,ARHGAP26,LHPP,COBL,CRTC1,TLR4,ZNF225,KCNAB1,GAN" Drug 4590_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "ACTN1,ADRA1D,ADRB2,ADGRB2,ARHGEF1,ARHGAP33,FOXN3,RAB28,CSF1,CSF1R,HDAC9,EXOG,DMPK,CDON,FEM1B,MRNIP,RGS17,SPEG,CINP,FYB1,SYT17,TJAP1,INPP5B,LIG4,GIT1,SLC11A2,PDE1C,PFKFB2,GRAMD1C,PTX3,BEND5,ZNF671,TCP11L1,ZNF821,SLC14A1,THSD1,MCF2L,TRIM2,SYNE1,OBSL1,CABIN1,TRIO,RUNDC3B,AMACR,VIPR2,LMF1,LAT2,WNT7A,NT5M,HPS4" Drug 5666_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "RALGAPA1,NDRG2,APOC1,CAST,KCNAB3,FOXN3,ASIC3,HAPLN1,CRY2,SNPH,EGFR,ERCC2,DLC1,ZNF589,FGF1,FGFR1,FHL1,KHDRBS3,OGA,NEU3,TDRKH,LPAR4,GSN,TJAP1,KCNN1,MGAT3,CNOT4,NPTX1,STRN3,LRP12,MINDY2,RASA3,ST6GAL1,PREX2,SLC8A1,SLC11A1,ZNF415,CDK19,RGL1,PHLDB1,TRIM2,DICER1,HEY1,CHST5,LAT2,ZNF711,GDPD5,ADAMTS9,EPM2A,HRASLS" Drug 6591_DN PHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "APBB2,APOC1,CDK10,EIF4G3,ALDH7A1,ST3GAL5,LARGE1,FOXN3,RAB26,ABCG1,AATK,DPH1,PTK2B,KAT8,TRMO,PDLIM5,GCNT2,MAP4K5,BACH2,KHK,LIFR,MAPT,MT1M,MX1,PDCD2,PPP5C,PRPH,SAMD9,CYBC1,WDR25,PTCH1,PTPRH,PTPRN2,TMEM231,NEK11,FBXW7,AMBRA1,KDM4B,SPTAN1,LHPP,PHLDB1,COBL,PDLIM2,OBSL1,CHST8,TK2,CHST5,HIRA,XRCC4,NT5M" Drug 7400_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "AP2A2,AMPD3,APC,PPFIA3,CDK13,MPDZ,MYRF,CFAP410,KYAT1,CCNT1,ARHGEF2,B4GALT6,BAG4,CREM,CNTNAP2,DZIP3,ARHGEF4,SGSM2,EDNRA,TRAF3IP2,B4GALNT1,DISC1,COPS8,HTATSF1,POLL,FAM69A,JAK2,KIF2A,KPNA5,MAPT,SERPINI1,PLCD1,NUDT11,SCN8A,SUPT20H,PEX26,SLC22A4,LIMCH1,ELOVL4,STX1A,KIAA1107,TIMP4,VLDLR,LMF1,ZBTB14,SPHK2,UPF3A,NT5M,ACTR3B,AAAS" Drug 5071_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "ASIC1,NME5,BIN1,EPB41L5,SLC4A4,SYNJ1,KYAT1,FOXN3,SOCS6,TAOK2,QKI,CPS1,CSF1,CNTNAP2,ZNF804A,RUSC2,SPOCK3,EXOG,FEM1B,MBNL2,IRAK4,ETV1,RRAGB,ZNF589,IQCG,KCNMB4,CNTRL,SHISAL1,LIG4,TM6SF1,ZNF862,NF1,PDE1C,PPARA,WDR25,PTCH1,GAL3ST4,TRAPPC13,ASAP3,DZIP1,KDM4D,ZNF415,SPTAN1,TK2,CABIN1,SSBP2,OSBP2,TFIP11,NAV3,FZD3" Drug 4963_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "SYN3,ASIC1,NDRG2,FAM131A,GYG2,MYRF,BAIAP3,CD86,CBFA2T2,CDH2,HOMER3,CPS1,SH2B1,CSF1,DBT,SPOCK3,EIF4G2,SPEG,PIPOX,FGFR1,AGAP2,SIGLEC8,ALDH1L1,GNG4,IRF8,INPP5B,KCNB1,KCNN1,KCNQ3,MAP2,MGAT3,MMP16,NTRK2,P2RY1,PDE4A,PLXNB1,PRKAR1B,RFX2,KCNIP1,SEMA6D,SCN8A,CNKSR2,SLC2A5,HECW1,TBCEL,WSCD1,ZEB1,AMACR,VIPR2,TIGD6" Drug 6338_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.48E-08 1.09E-03 4.58E-06 5.16E-05 50 196 "ASPHD1,CDC14B,PPP4R4,MADD,CDK13,SLC4A4,STX16,KIF1A,CFLAR,ST3GAL5,CACNA1I,NRXN3,AKAP7,SH2B1,AATK,CSF1R,CTH,RIPOR2,EGFR,FGF13,DISC1,ZNF276,GLYR1,LPAR4,KHK,KIFC3,LIG4,MGAT3,MMP16,NF1,NNAT,CCSER2,RETREG1,STRN3,MINDY2,PRKAR1B,MAPK7,DZIP1,COA1,SMARCD3,IFT122,SNCA,TSNAXIP1,LHPP,PHLDB1,CRTC1,TIMP4,TK2,XRCC4,REEP1" Drug ctd:D003024 Clozapine CTD 2.83E-08 1.24E-03 5.00E-06 5.64E-05 82 392 "ADCY5,AXIN2,ADORA2A,AGT,OSBPL8,CACNA1A,CAMK2A,CAMK2B,CCK,DCLK1,NUMBL,CHN1,CLTB,ABCG2,CLOCK,CRHBP,ABCG1,CST3,DRP2,EGR3,ERBB2,ERBB4,PPP1R1B,HPCAL4,CAMKK2,ABLIM2,GABBR1,CHL1,GABRB3,GAD1,DISC1,CPLX2,NTNG2,GRIA2,GRIK5,GRIN2C,HMGCR,IGF1,JAK2,KCNH2,LSS,MBP,NFE2L2,NPY,NPTX2,PDE4A,PDE4B,PDE1B,ABCB1,PKM,PPM1B,PPP1R1A,PPP3CA,PPP5C,PRKACB,PRKCB,MAPK3,MAPK9,RELN,WBP1L,RASGRF1,RGS4,RORB,KCNIP3,STX1B,SGK1,SNAP25,SPP1,SST,STX1A,STXBP1,ARHGEF9,PLCB1,ARC,SYN2,SYT5,TRIM2,THRA,VSNL1,MAP3K12,SLC17A7,RTN4" Drug 4226_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "NME5,C1QTNF3,PKP4,GYG2,MAGI1,FOXN3,QKI,SULT4A1,CNTFR,ERC2,PHF14,SGSM2,CHRDL1,DYNC1I1,EDIL3,ETV1,AGAP2,ERAP1,SYT17,PCDH17,GNAL,ATXN2L,VSIG4,TJAP1,MAP2,MSR1,LYRM9,CLDN11,NECAB2,CEP41,PTN,PTPRN2,MARCH1,ENOX1,RGS4,KCNIP1,ASAP3,FBXO11,ZNF334,LIMCH1,NFASC,SYN2,MCF2L,TBCEL,DOCK9,ICAM5,CA14,LAT2,KCNAB1,EPM2A" Drug 6614_UP Apramycin [37321-09-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ADCY6,ADD2,ADORA1,EPB41L5,ATP2B2,ADGRB3,BMPR1B,ENTPD2,DGKI,ARHGAP33,CRLF1,SPOCK3,DNAH9,NCALD,NRN1,DLC1,AGAP2,EFCAB2,OGA,SRCAP,PRUNE2,ATXN2L,ICA1,C2orf72,KCNB1,KCND2,MAP2,AFDN,MMP16,NRCAM,PALM,PLCB2,PPP2R2B,PTCH1,ZSCAN32,KCNIP1,SLA,PEX26,SLC11A1,ZNF334,DOK5,IZUMO4,ARC,TACR1,TCF4,CHST8,TRO,CA14,OSBP2,KCNAB1" Drug 5741_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "SYN3,APAF1,LGR5,CACNA1A,CACNA2D2,PLEKHB1,TAOK2,NRXN3,RAB26,CNR1,CNTN1,CNTNAP2,PYGO1,DAPK1,MFAP3L,EXOG,PLXNC1,ERAP1,STON1,GSTM5,AP4S1,SMAD1,ADAM11,AFDN,MMP16,MSR1,LYRM9,NF1,NTRK3,PALM,PCDH9,NEK11,KCNIP1,SEMA6D,SLC6A8,OGDHL,TSNAXIP1,SPTAN1,DDN,PCDHGA10,SYNE1,DOCK9,TNS1,AMACR,RPRM,OSBP2,VAV1,ZBTB14,SLC30A3,SEMA3B" Drug 4739_UP Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ALCAM,APBA2,APC,APOC1,CDK13,MARK4,RAB33A,NECTIN3,CNTNAP2,DCAF4,TMCC2,DTNB,IGSF6,PTK2B,DLC1,DLL3,GATM,SRCAP,MALT1,ADAMTS13,ICA1,TJAP1,KCNH2,SMAD1,MAPT,ADAM22,TAGLN3,NF1,OPRL1,PCSK5,ENOX1,RGS3,RPS6KA2,SCN8A,RASA3,FUZ,LIMS2,SNAP25,SNCA,ZNF415,PEG10,RBM26,TROVE2,JMJD6,TNS1,TPM1,TRPM2,SLC30A3,ITM2C,EPM2A" Drug 4418_UP Ethionamide [536-33-4]; Up 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "SYN3,ASIC1,AP2A2,SEMA6A,LTBP4,BIN1,APAF1,KCNAB2,GAS7,DDO,DNAH17,RASL11B,BAIAP3,CALB2,HIP1R,RUNX1T1,SEPT7,CACNA2D2,TAOK2,TPP1,AKAP7,WHRN,CYBB,SPOCK3,EDN1,EIF4G2,TNK2,ZNF589,FER,ANKFY1,FYB1,GAD1,INPP5B,MEF2C,ADAM22,ENPP2,PFKFB2,ENOX1,FBXW7,SH3BP2,ARHGEF40,LIMCH1,SNCA,HECW1,CDK19,TNS1,DNALI1,ITM2C,FAM13C,PHTF2" Drug 5244_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "BIN1,AMT,ANK2,SLC2A11,ARHGEF2,CLGN,CACNA2D2,CLTB,SPOCK2,KLHL3,TMCC2,E2F5,PLXNC1,EPHB1,PTK2B,DLC1,POLL,GNAO1,PRUNE2,GRB10,IRAK3,KCNN1,KCNN2,KIT,LSS,NPY,NTRK2,PCDH9,SERPINI1,PLCD1,LRP12,ZSCAN32,KHDRBS2,PNMA8A,KCNIP1,SH3BP2,FAM214B,DOK5,IZUMO4,SYT5,TBL1X,TK2,RUNDC3B,UBE2H,FLRT2,VLDLR,NT5M,EVI5,PLSCR4,PARP11" Drug 3195_UP Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "FZD9,ALCAM,FAM135A,APAF1,APC,ARHGDIG,AZGP1,CFAP410,KCNAB3,DLGAP2,B4GALT6,COL9A3,CNTNAP2,MFAP3L,RUSC2,DTNA,DUSP9,EDNRA,C3orf18,NCALD,DLC1,FLT1,FYN,PCDH17,GLYR1,TOX3,SMAD1,MATN3,AFF1,MMP17,MYT1,PALM,PDE4D,ENPP2,PLCB2,CCDC40,RFX2,ZFHX4,OGDHL,SNAP25,SP4,DDN,ARC,SYN2,ADGRL3,HIF3A,VGF,XRCC4,ZNF45,GDPD5" Drug 3189_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ALK,AMT,ANK2,GAS7,DDO,ARHGDIG,CA12,HAP1,RUNX1T1,CLDN10,FAM131B,RIPOR2,JAKMIP2,DTNA,DUSP9,ING4,TNK2,CALCRL,ETV1,ACSL4,AGAP2,PDLIM5,KHDRBS3,ADAM28,PCDH17,TOX3,GNAL,GNAO1,TDRKH,GRIN2C,GRM8,ICA1,KPNA5,MARK1,LRP1B,MYCN,MYO7A,NOVA2,TRHDE,C1orf54,FAT4,RGS12,SCN8A,SH3BP2,KDM4B,SAMSN1,PLCB1,SYNE1,FAM189A1,SLC19A3" Drug 5519_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ABHD6,ADRA1D,NME5,AK2,ALK,BIN1,CDC42BPA,APBA2,SEMA4G,PLA2G4C,ATP6V0A1,KALRN,SLIT2,TPP1,CNR1,CNTFR,CNTN1,AKAP7,CSF1,SUSD5,ZNF337,RASSF2,TBC1D5,SPOCK2,C2CD2L,SGSM2,DTNA,FHL1,TPK1,CAMKK2,LYVE1,POLL,C2orf72,INPP5B,KCNH2,SAMD14,ZSCAN32,ROBO1,RPS20,RASA3,ANKRD6,COA1,SNCA,IQSEC2,PHLDB1,STX1A,TK2,ZNF711,MAP3K12,SEMA3B" Drug 5704_UP Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ASIC1,SYT13,BEGAIN,BIN1,CDC14B,ARHGDIG,SYNJ1,CACNA1G,CALB2,CAMK2B,SNCAIP,RGS6,PDE4DIP,DMPK,HS3ST2,DTNA,MRNIP,ETV1,FGF13,AFF2,RUNDC3A,TDRKH,PCLO,TJAP1,KCNH2,KCNJ16,MGAT3,AFDN,ADAM22,PDE1C,NLE1,PLCD1,RASGRF1,RGS12,CPEB3,KANSL3,MAPKBP1,SOX15,ARHGAP26,TROVE2,SYN2,SYT5,TAL1,PCDHA2,PARD3,VLDLR,LAT2,ADAMTS9,SEMA3B,SLC17A7" Drug 4580_DN Beclomethasone dipropionate [5534-09-8]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ALK,ARHGDIG,ATP1A3,SYNJ2,CACNA1A,CAMK2B,TPP1,STOML1,HOMER3,COL9A3,CRY2,CSF1,CSF1R,ARHGEF4,LYPD1,SGSM2,DPH1,DTNA,CELSR3,MBNL2,ING4,TNK2,MRNIP,HSD17B14,FGFR1,SCARA3,FYB1,GPER1,CNTRL,IL6ST,GIT1,CLDN11,PDE4B,FA2H,GRAMD1C,ZNF821,DZIP1,ANKRD6,ARHGAP26,LHPP,PDLIM2,ADGRL3,OBSL1,CRTC1,CHST8,THRA,TIMP4,WNT7A,SPHK2,NT5M" Drug 5749_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ALK,PPP4R4,CA8,CBFA2T2,AP4M1,CRLF1,CHN2,RAB28,PLAA,TPP1,SULT4A1,ABI3BP,SLITRK5,PPP6R2,GIT2,STX2,FGFR1,OGA,USP19,MSL3,GPD2,GUCY1B1,HSF2,MIA2,ADAM22,ZNF862,PFKFB2,STRN3,TMEM104,CNTLN,ELOVL2,PTPRE,KCTD17,SUGCT,MAP6D1,ZNF415,SS18,CEP68,EXOC7,KIAA1107,GPR161,VIPR2,REEP1,UPF3A,MAP3K12,NT5M,NAV3,KCNAB1,TIGD6,DPF3" Drug 3351_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ACHE,ADRA1B,NME5,CDC42BPA,FAM131A,CDK10,CDK13,RIPK1,BAIAP3,LDLRAD4,ARHGEF1,SCARB1,ARHGEF2,TAOK2,NECTIN3,ENTPD4,DOCK4,RUSC2,HIPK3,MBNL2,APC2,PTK2B,FGFR1,FGFR3,FHL1,DLL3,GAD1,SIGLEC8,GNAL,GRM8,NF1,CDK18,PFKFB2,STRN3,ZSCAN32,PTPRH,C1orf54,ASAP3,DHX30,CXXC4,COA1,ZC3H13,DMXL2,TNS2,PCDHA6,TNS1,UCHL1,PLPPR2,ZNF45,DNALI1" Drug 5411_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ADD2,AP2A2,KIAA1324,DOC2A,SEMA7A,APC,CDC14B,ADAM23,SGCE,CALB1,DCLK1,ARHGAP33,CRLF1,LY86,WHRN,ARHGEF4,CYBB,HEPH,GSDME,HIPK3,EIF4G2,VPS13B,ERCC2,RRAGB,PRELID3A,ADAM28,PCDH17,POLL,BACH2,TJAP1,KIF5A,MITF,MSI1,MSR1,MYO7A,PFKFB2,PPARA,PPP5C,ZFHX4,SH3BP2,ST6GAL1,PKNOX2,SLC11A1,SMARCD3,ZNF423,SAMSN1,TBCEL,FLRT2,SPHK2,KCNAB1" Drug 7286_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "APC,SLC4A4,ATP6V0A1,SCAPER,BAIAP3,PLEKHB1,B4GALT6,NRXN3,STOML1,QKI,HOMER3,PCYT1B,HAPLN1,ABCG1,DZIP3,RIPOR2,DTNA,EDNRA,EIF4G2,DENND4A,ETV1,VPS26C,RRAGB,IQCG,FYB1,DENND2A,GNG4,GRM8,HLF,TJAP1,LIG4,MIA2,NDP,NPTX1,NLE1,MAPK7,CNNM2,BCAS3,TMEM231,SH3BP2,PEX26,SLC6A8,UNC5B,NXT2,ASTN2,CABIN1,TRO,UGT8,VIPR2,KCNK12" Drug 3875_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ABHD6,NDRG2,ADORA2A,TRMT9B,BIN1,PRX,NRP2,CACNA1I,CAMK2B,RCBTB2,TAOK2,SULT4A1,LY86,CNTFR,DAPK1,SPOCK2,ETV1,DISC1,ALDH1L1,ADAM28,GLYR1,MSL3,ADAMTS13,HLF,AFDN,ADAM22,NCF2,NF1,NNAT,CNOT4,CLDN11,SERPINI1,PLTP,STRN3,MINDY2,ELOVL2,KCNIP1,CLIP1,CSRNP3,SH3GL3,KDM4B,SPP1,CDK19,POGZ,TBL1X,DMXL2,DOCK9,DNAH7,ZNF45,KCNAB1" Drug 6400_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "APAF1,APBA2,APC,GAS7,PPP4R4,ADGRB2,BTK,BAIAP3,CAMK2B,ARHGEF2,TAOK2,STOML1,SLITRK5,MFAP3L,DTNA,EFCAB2,DISC1,TDRKH,GPER1,CNTRL,CACFD1,SHISAL1,IGF1,ITGA7,ADAM22,PFKFB2,CEP41,PRKAR1B,PTCH1,MARCH1,BEND5,RGS3,KCTD17,RNASE1,CARF,RPS20,KCNIP1,SH3BP2,ASAP3,DZIP1,SPP1,DDN,TAL1,TBCEL,TCF4,CDK20,TRO,CA14,RPRM,SPHK2" Drug 5641_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "ASIC1,ADRA1D,APAF1,CDC14B,ADAM23,KSR1,HAP1,CLTB,WHRN,SNPH,TNK2,FGF1,FGF13,FGFR1,FGFR3,FHL1,FOLR2,CAMKK2,SIGLEC8,GFER,LYVE1,RUNDC3A,PRUNE2,GRIK5,ATXN2L,ITGA7,KCNB1,KCNH2,MAN2A2,ADAM22,ZNF862,NPY,GPR85,PFKFB2,FXYD1,DCHS2,RELN,ZSCAN2,ZDHHC14,FRMPD1,KIF13A,FAIM2,SPP1,SYN2,ZEB1,RPGRIP1L,TRPM2,SPHK2,SLC30A3,KCNAB1" Drug 2798_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "NDRG2,ADD2,KIAA1324,ALCAM,SEMA7A,APAF1,PDE8B,MARK4,RASL11B,ALDH7A1,CAMK2G,CDO1,ASIC3,RCHY1,DCAF4,DUSP9,HIPK3,STX2,FGF12,IQCG,PDLIM5,CAMKK2,DLL3,OGA,SRCAP,MSL3,ICA1,MAP4,MMP16,ADAM22,NELL2,PCDHGC3,SLC25A23,LRP12,RETREG2,RGS4,RGS12,SBF1,RASA3,SH3BP2,ASAP3,CDK19,ZBTB43,KIAA1107,TBCEL,WSCD1,PCDHA5,LAT2,SEMA3B,KAT6A" Drug 5668_UP Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "AGT,BEGAIN,APBA2,SEMA4G,ARHGDIG,RGS11,RGS9,CALB2,CDO1,FOXN3,TPP1,GIT2,EGR3,TENM1,COQ7,ERBB2,NRN1,FGFR1,FHL1,RUNDC3A,RAB30,PCLO,SPACA9,BTN2A1,GSN,TJAP1,KCNH2,TAGLN3,NF1,CNOT4,P2RY1,RETREG1,LRP12,VPS13C,PTX3,CEP97,RGS12,KCTD17,CCDC102B,ZFP2,SH3BP2,SYBU,SNCA,IZUMO4,KIAA1107,DOCK9,CRTC1,ZNF34,ANKS1B,SEMA3B" Drug 6776_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.96E-08 1.30E-03 5.00E-06 5.64E-05 50 197 "SEMA6A,BIN1,APC,APOC1,PPFIA3,CDK13,MARCH3,ATP6V0A1,SYNJ2,CAMK2B,FOXN3,RAB28,AKAP7,CRY2,ARHGEF10,DTNA,CNNM1,ING4,FHL1,RAB30,HTATSF1,GNG4,GPD2,GSN,MAPT,LYRM9,SLC25A23,LRP12,FA2H,ZDHHC14,NEK11,SBF1,ZNF821,SPATA7,TSPYL2,LHPP,NXT2,PLCB1,ARC,ASTN2,EXOC7,IQCE,TNS2,UBTF,PLPPR2,SPHK2,REEP1,MAP3K12,SEMA3B,MPPE1" Drug 4344_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.97E-08 1.30E-03 5.00E-06 5.64E-05 47 180 "ADRB2,APAF1,EPB41L5,ST3GAL5,HIP1R,USP2,NRXN3,ABCG1,PDE4DIP,PLPPR4,RGS17,TAOK3,FGFR1,BAIAP2,FYN,CYP46A1,FAM69A,KCNH2,MAP2,MAPT,MMP16,PALM,PCDH9,SERPINI1,RETREG1,GRAMD1C,PRPH,TMEM104,PTCH1,ENOX1,RGS4,FBXW7,SH3GL3,ASAP3,KDM4B,HECW1,ARHGAP26,NFASC,THSD1,ELOVL4,RGL1,SYT1,RUNDC3B,LAT2,TRIM9,EVI5,SLC17A7" Drug 4632_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.07E-08 1.35E-03 5.16E-06 5.81E-05 45 169 "ADCY6,ADRB2,MTUS1,NME5,ARNTL,ST3GAL5,FOXN3,WHRN,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,RGS17,TAOK3,FGFR1,BAIAP2,FYN,STON1,GUCY1B1,BACH2,LIFR,MEF2C,MMP16,TAGLN3,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,ENOX1,RGS4,RTN1,FAM102A,SH3GL3,KDM4B,ARHGAP26,THSD1,ELOVL4,RGL1,PHLDB1,SYT1,COBL,SSBP2,PLSCR4" Drug 909_UP HC toxin from Helminthosporium carbonum; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.33E-08 1.46E-03 5.48E-06 6.18E-05 46 175 "ALCAM,PPFIA3,ARNTL,BMP7,ST3GAL5,BAIAP3,CLGN,UBE2L6,AKAP12,ARMCX2,TSPAN5,MBNL2,RASGRP2,FHL1,FYN,STON1,GPR37,RNFT2,MITF,MPP2,MXI1,NEK1,PDE4A,PMP22,PKIA,PRPH,PTCH1,GSTCD,SH3BGR,SH3GL3,PPM1E,LIMCH1,THSD1,ELOVL4,RGL1,STXBP1,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 3087_UP Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.36E-08 1.47E-03 5.48E-06 6.18E-05 49 192 "SYN3,AMH,BIN1,CDC42BPA,ARRB1,DNAH17,CACNA1G,RAB33A,CREM,HAPLN1,CRYBB1,NCOR2,ABCG1,SIPA1L1,USP6NL,DOCK4,CDON,EDIL3,C3orf18,EPHB1,FGFR1,BAIAP2,PDLIM5,ALDH1L1,GNG4,PADI2,KCNJ5,MAP4,MYCN,NEFM,PCDH9,PDE4B,GPR173,MTRF1L,PLXNB1,MARCH1,PID1,TMEM255A,PNMA8A,FRMPD1,SLC8A1,ARHGEF40,SLC11A1,IZUMO4,SYN2,SZT2,CHST8,TNS1,PCBP4" Drug 2738_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.36E-08 1.47E-03 5.48E-06 6.18E-05 49 192 "KSR1,CACNB4,DLGAP1,CHN2,PICK1,COL9A3,NCOR2,RIMS2,SPOCK3,CDON,MBNL2,CORO2B,ZNF44,SIGLEC8,SEPT9,HNMT,MAPT,MGAT3,AFDN,ADAM22,MYO6,PDE1C,PPP1R1A,PTPRB,RASGRF1,KHDRBS2,RGS4,SUGCT,NEK11,SCN2B,FRMPD1,FERMT1,NLGN1,SNAP25,ZNF415,SSTR2,PLCB1,SYT5,TRIM2,PCDHGB6,THRA,TIAM1,TRIO,TRO,OSBP2,LMF1,KLC2,KCNK12,JPH3" Drug 6388_UP Orlistat; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.36E-08 1.47E-03 5.48E-06 6.18E-05 49 192 "KIAA1324,AMPD3,APOC1,CDK10,PDE8B,SYNJ1,BAIAP3,CD86,CBFA2T2,CLTB,COL9A3,CSF1R,PYGO1,DAPK3,EXOG,ETV1,EYA1,REEP2,DCTN2,DENND2A,SIGLEC8,CPLX2,POLL,GRM8,IRAK3,ICA1,KCNB1,MAP2,MMP16,MSI1,NF1,C19orf57,MINDY2,PPP5C,PRKAR1B,PRKCB,RNASE1,ZNF671,PKNOX2,SLC11A1,PDZRN3,UNC5B,MCF2L2,PLCB1,TRIO,AMACR,HIRA,FLRT2,ZNF154" Drug 7519_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "MTUS1,MARCH3,STX16,MPDZ,CFLAR,MAGI1,TAOK2,CLCN3,RAB26,NRG2,FAM131B,SPOCK2,EXOG,DMPK,FEM1B,MBNL2,VPS26C,FHL1,ANKFY1,EFCAB2,SYT17,DISC1,GLYR1,HTATSF1,CACFD1,GUCY1B1,IL6ST,MBD1,MIA2,MN1,MX1,NFYA,PALM,SERPINI1,PLXNB1,BEND5,REV3L,KIF13A,USP33,IQSEC2,ZBTB43,SYNE1,AP4E1,TK2,R3HDM1,HIRA,LMF1,WNT7A,EMSY,PHTF2" Drug 3810_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "MTUS1,AMPH,AMT,APAF1,APC,CDC14B,PRX,PDE8B,ATP2B2,SLC2A11,N4BP2L1,PROM1,BMP7,LDLRAD4,RUNX1T1,USP2,KIAA0319,DNAH9,MBNL2,ERBB2,EZH1,SEMA4D,CPLX2,ALDH1L1,SRCAP,GPR75,KCNH2,KCNJ5,MGAT3,AFDN,NF1,NOVA1,NPTX1,NTRK2,LRRN3,PRKAR1B,SAMD9,KHDRBS2,RNASE1,RNASEL,SH3BP2,SLC2A5,PDZRN3,IZUMO4,MCF2L,TK2,RIMBP2,TPM2,RUNDC3B,HRASLS" Drug 2271_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "AP2A2,LTBP4,AMPD3,GAS7,MARK4,CACNA1I,RHBDL1,CDH2,ASIC3,SULT4A1,LY86,CRMP1,CSF1,ARHGEF10,CDON,MBNL2,ING4,ELN,SCARA3,DCTN2,EFCAB2,CAMKK2,ERAP1,ADAM28,CSDC2,HPGDS,GNAO1,GPER1,TJAP1,KCNJ5,MAP2,MEF2C,MID1,MX1,CNOT4,NPY,PCDH9,LRP12,ZFP2,FRMPD1,FNDC3A,SLC11A1,COA1,DDN,SLC19A3,CRTC1,UGT8,ZNF45,SPHK2,SLC17A7" Drug 6304_DN Nitrendipine [39562-70-4]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "MTUS1,EP400,APLP1,C5,KYAT1,CNOT8,ARHGAP32,SPOCK3,FEM1B,DENND4A,FCGRT,TRMO,OGA,ERAP1,INPP5K,MSL3,GPR37,MAN1B1,INPP5B,MAP4,TM6SF1,MID1,MN1,TAGLN3,NFYA,FA2H,FSD1,PRPH,CNNM2,GAL3ST4,RPS6KA2,SBF1,FAM102A,ASAP3,FUZ,COA1,TMCC1,FNBP1,STX1A,ARHGEF9,EXOC7,IQCE,WSCD1,TNS2,PARD3,CABIN1,PLPPR2,XRCC4,UPF3A,ST7" Drug 601_UP MK-886; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "BRAP,MTUS1,CDC14B,SEMA4G,HAP1,CD86,SCARB1,PICK1,CNTFR,AATK,ARHGEF10,DGKG,C2CD2L,KLHL3,DTNA,SUGP2,MBNL2,HSD17B14,SPEG,ZNF589,AGAP2,TRMO,NSG1,SYT17,GSTM5,RNFT2,NCKAP1L,KIF2A,STMN1,MMP17,NACA,NNAT,CNOT4,NPR2,SETD4,PDE1C,PLXNB1,SUSD4,GAL3ST4,SH3BP2,FERMT1,SLA,PREX2,KDM4B,CLSTN2,ARHGEF9,CHST8,LMF1,SLC17A7,UBE3B" Drug 6046_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "BIN1,APLP1,CFAP410,CALB1,TAOK2,EPS15L1,ARHGEF6,AKAP6,CREM,IPCEF1,KLHL3,EXOG,EIF4G2,MTSS1L,CORO2B,CAMKK2,KHDRBS3,NSG1,FYB1,FYN,GNAO1,PRUNE2,GPR37,TJAP1,MAP4,MEF2C,ADAM22,TAGLN3,NOVA2,PPP5C,MAPK7,MASP1,RELN,CNTLN,RGS12,SCN2B,MRAS,SLA,FAM214B,SLC12A4,LIMCH1,SNAP25,SNCA,DOK5,IZUMO4,ARHGAP26,KIAA1107,PCDHA3,HIF3A,LAT2" Drug 1519_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "ASIC1,KIAA1324,CDC42BPA,APBA2,KCNAB2,APBB2,GAS7,ARHGDIG,SLC2A11,SYNJ2,CACNA2D1,CAMK2B,CBFA2T2,ARHGAP33,CACNA2D2,TPP1,BAG4,IPCEF1,HSD17B14,RASGRP2,REEP2,HPCAL4,SRCAP,USP19,ADAMTS13,GUCY1A1,TJAP1,KCNB1,MAP4,MID1,NEK1,CEP41,GRAMD1C,PRODH,PRPH,CNNM2,CEP97,STUM,PKNOX2,MAPKBP1,TMCC1,DOP1A,KDM4C,ARHGAP26,ZBTB43,ELOVL4,DOCK9,TIAM1,UGT8,ZNF154" Drug 6800_UP Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "ADCY6,TRMT9B,KCNAB2,PRX,ARRB2,ALDH7A1,CFLAR,CACNB4,HIP1R,CBARP,CNTN1,RGS6,PDE4DIP,DAPK3,SPOCK2,DBN1,ARMCX2,JAKMIP2,VPS13B,OLFM1,FHL1,PDLIM5,FYN,GFER,GLI2,INPP5B,JAK2,MID1,ZNF862,PAX6,PDE1C,PDE4A,NLE1,PRKAR1B,NLGN1,SLC11A1,SLC12A4,CDK5RAP2,SMARCD3,ZNF415,TROVE2,SYT5,TNS1,FAM155A,UBE3A,PLPPR2,ZNF711,EVI5,ITM2C,MPPE1" Drug 5095_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "AGT,TRMT9B,PKP4,APBB2,APOC1,PPP4R4,PDE8B,SLC4A4,N4BP2L1,BAIAP3,CFAP410,MAGI1,PICK1,RIMS2,DRP2,COQ7,MTSS1L,CDKL3,DLC1,FGFR1,AGAP2,EFCAB2,CAMKK2,SIGLEC8,SRCAP,RUNDC3A,GNAO1,GRM8,ITGA7,P2RX7,GPR85,PLCD1,PTPRN2,TMEM231,CCDC40,C1orf54,GAL3ST4,RNASEL,DOK5,ZBTB43,CEP68,SYT5,CRTC1,PCDHA5,AP4E1,ZNF34,TK2,TRIO,TRO,VIPR2" Drug 3583_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "SYN3,ADORA1,SEMA6A,BIN1,SEMA7A,KCNAB2,CACNA1I,BAIAP3,CAMK2B,CBFA2T2,CHRNA4,TAOK2,HOMER3,FAM149A,SNCAIP,PDE4DIP,HDAC9,SPOCK2,AASS,EIF4G2,ABCA8,FGFR3,DISC1,GLI2,LPAR4,ITPKA,SMAD1,MGAT3,SAMD14,NF1,TREM2,PDE1C,PDZRN4,SNRK,PTCH1,PTN,ZSCAN2,RGS3,RGS12,RPS6KA2,SCN2B,ZNF821,PKNOX2,SNCA,PEG10,CLSTN2,OBSL1,TRPM2,TUBB1,GDPD5" Drug 2649_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "SYN3,ADGRF5,TRMT9B,SEMA4G,RGS20,PLA2G4C,ATP6V0A1,RGS11,ARHGAP33,SLIT2,FAM149A,RCHY1,RIMS2,DBT,TMCC2,DTNB,HSD17B14,RASGRP2,NCALD,NRN1,DLC1,ZNF589,OLFM1,FGFR1,TRAF3IP2,ALDH1L1,GCNT2,AHDC1,USP19,GNAL,GNAO1,GRB10,ATXN2L,ICA1,KCNJ5,NPTX1,NLE1,MBOAT7,PPP5C,PRPH,PTN,CCDC40,RGS12,GSTCD,RGL1,TLR4,VLDLR,DNALI1,GDPD5,ADAMTSL3" Drug 6503_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "LTBP4,APBA2,ADAM23,CA4,CAMK2G,RUNX1T1,ARHGEF1,DGKI,STOML1,CNTFR,COL9A3,MAML1,SPOCK2,KIAA0319,TMCC2,DTNA,ANKMY1,TPK1,ALDH1L1,RUNDC3A,PRRC2B,GPER1,PTPRT,SYNPO,ICA1,ITPKA,KHK,KPNA5,MAP4,NCF2,NEFM,NPY,NOVA2,PFKFB2,PLCD1,FSD1,PTPRB,RFX3,MRAS,FRMPD1,ASAP3,PEG10,ARHGAP26,ATP10B,IQCE,ZNF34,SLC44A1,OSBP2,WIPF1,PLSCR4" Drug 6494_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "NDRG2,AP2A2,PPP4R4,ARHGDIG,MARK4,N4BP2L1,NRP2,CBFA2T2,TPP1,NCOR2,CSF1R,RIPOR2,ELMO1,RUSC2,DMPK,RCAN1,EDN3,NRN1,FGFR1,ALDH1L1,SRCAP,GNAL,GPER1,GRB10,GRM8,SOX21,GUCY1A1,HLF,ITGA7,MEF2C,MX1,MYCN,OGG1,PDE1C,SMIM7,PTX3,RFX3,FBXW7,FRMPD1,SLC11A1,HECW1,ATP10B,ARC,IQCE,PCDHGB6,XRCC4,SLC30A3,ADAMTS9,SEMA3B,JPH3" Drug 6496_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "NME5,C1QTNF1,MARK4,CFAP410,CACNA2D1,CAMK2B,DGKI,HOMER3,CNTFR,ENTPD4,VCAN,MAML1,SPOCK2,RUSC2,RCAN1,DTNA,EDNRA,EGR3,PLXNC1,ERCC2,HPCAL4,ANKFY1,SRCAP,TDRKH,SOX21,ITGAM,KCNB1,KCNN2,LSS,MAN2A2,MBD1,ADAM22,CNOT4,RETREG1,NLE1,PPP5C,PRPH,RELN,SAMD9,PREX2,PKNOX2,SNCA,UNC5B,PEG10,WSCD1,TRIM2,HIF3A,PARD3,LAT2,XRCC4" Drug 3548_UP Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "ADORA2A,NME5,SEMA6A,APC,SPTBN4,MARK4,ATP1A3,GYG2,SGCE,CALB2,PLEKHB1,CNTFR,FAM149A,SLITRK5,PHF14,DBT,SV2B,SPOCK3,CDON,CORO2B,ST3GAL6,ZNF589,SEMA4D,TMEM8B,INPP5K,GATM,GPD2,GPER1,GSTM5,IRAK3,MARK1,MGAT3,MID1,LYRM9,NF1,LRP12,SAMD9,PTN,CRTAC1,RGS12,RPS6KA2,SEMA6D,PKNOX2,SNCA,SPTAN1,WSCD1,TCF4,TNS2,SEMA3B,KCNAB1" Drug 6687_DN Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "PPFIA3,SHROOM2,CDK10,KIF1A,PTBP2,CAMK2G,KRIT1,AKAP7,IQCK,ARHGEF10,CNTNAP2,FBXL5,KLHL3,SGSM2,CHRDL1,DENND4A,ST3GAL6,TRMO,NBEA,ATP2C1,TXNL4A,BACH2,SCIN,FAM69A,TM6SF1,SCAMP5,MYO9A,NDP,PIK3R1,PLCD1,GRAMD1C,PTPRN2,TMEM231,PID1,C1orf54,FAT4,MSANTD2,TRAPPC13,MAPK12,SUPT20H,ASAP3,FBXO11,ST6GAL1,SIRT2,LIMCH1,UHRF1BP1L,TMEM121,CABIN1,TPM2,ZKSCAN5" Drug 3053_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.53E-08 1.55E-03 5.48E-06 6.18E-05 50 198 "NDRG2,MTUS1,SYT13,CDC42BPA,DDO,CDC14B,PLA2G4C,NRP2,THSD7A,USP2,SYNGR3,SEPT7,CDO1,NDST3,LHX2,SULT4A1,CNR1,CNTFR,COL9A3,CSF1,PDE4DIP,HEYL,CALCRL,EPHB1,STX2,PTK2B,HPCAL4,SIGLEC8,KCNMB4,SHISAL1,IL6ST,KCNF1,KCNJ5,NRCAM,PLEC,FSD1,MAPK7,PTPRN2,ZMAT4,RGS12,ZFHX4,EPN2,PKNOX2,PEG10,TBCEL,WSCD1,PCDHGB6,TK2,TRIO,FZD3" Drug 1471_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.57E-08 1.57E-03 5.53E-06 6.23E-05 47 181 "ALCAM,SRPX,MARK4,BMP7,ST3GAL5,RAB29,BAIAP3,HAP1,CAMK2B,CLGN,ARMCX2,MBNL2,EXTL2,HPCAL4,IQCG,FYN,CYP46A1,RAB40B,STON1,MXI1,ZNF862,NEK1,PCDH9,PDE4A,SERPINI1,RETREG1,PLCD1,GRAMD1C,PRPH,SH3BGR,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,LIMCH1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,UBE2H,SLC30A3,SLC17A7" Drug CID000000813 potassium Stitch 4.01E-08 1.76E-03 6.11E-06 6.88E-05 171 1009 "KCNH8,ASIC1,METAP1D,ADCY5,ADCY6,ADCY8,ADD1,BRAP,ADORA1,ADORA2A,ADRB2,SLC24A4,AGT,BBOX1,DPP10,PHF12,KCNAB2,APOC2,ATP1A1,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,AZGP1,HCN2,NAE1,CACNA1I,CACNA1G,WASF1,CA4,CACNA1A,CACNA1B,DDR1,CACNA2D1,CACNB4,CALM1,CAMK2B,CBS,CCK,KRIT1,CBFA2T2,LRBA,LONRF2,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CLCN3,MYL6B,CLTC,ABCG2,COL4A5,CPS1,CRYM,CNTNAP2,PLCXD3,HDAC4,SACS,SV2B,DMPK,SLC12A6,DPP6,DTNB,EDN1,EDN3,EDNRA,RASA4,F5,PTK2B,SLC9B2,ATP2C1,GABRG1,GABRG2,GCK,MSTN,GGT7,GGT5,CRCP,DBF4,GLYR1,POLL,KCNMB4,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GUCY1B1,MAP4K5,HBA1,TNFAIP8L3,HMGCR,MYLK2,IGF1,SCIN,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNN1,KCNN2,KCNN3,KCNQ3,KHK,MAT2A,AFDN,MYO5A,FXYD7,NBL1,NPY,NPR2,NUCB2,OPRL1,P2RX7,P2RY1,ENPP2,GNG2,PIK3C2A,PIK3R1,PKD1,PKM,PLCB2,PLCD1,FXYD1,MBOAT7,PRKACB,PRKCB,MAPK3,KLK6,PTCH1,RGS4,RPL15,RPS6KA2,KCNIP3,KCNIP1,RYR3,SCN7A,SGK1,SLC8A1,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SNAP25,SST,SSTR2,STX1A,PLCB1,SYN2,TPCN2,SYNE1,CYB561A3,PIK3R5,NPL,KCNE5,SGK3,KCNK12,KCNT2,SLC38A1,KCNAB1,WNK3,ST8SIA2" Drug 3693_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.01E-08 1.76E-03 6.11E-06 6.88E-05 49 193 "KCNAB2,CDC14B,CDK13,NCOA1,RASL11B,KIF1A,SYNJ1,CAMK2B,FOXN3,CHN2,B4GALT6,TAOK2,PLAA,IQCK,SH2B1,PPP6R2,DAPK3,DMPK,CDON,MBNL2,PLXNC1,STX2,FGFR1,CSPG5,OGA,SRCAP,HTATSF1,SPACA9,ELOVL5,HNMT,KIFC3,MAN2A2,MAPT,NPR2,PCDH9,SERPINI1,PIK3R1,PTN,PTPRB,RGS12,NEK11,MRAS,DOK5,LHPP,ARC,RPGRIP1L,TNS1,AMACR,RPRM" Drug 4151_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.01E-08 1.76E-03 6.11E-06 6.88E-05 49 193 "AK2,SEMA6A,ALK,CFLAR,SYNJ2,CACNA1G,CALB1,CALB2,KALRN,CAMK2B,SLC16A4,CLGN,TAOK2,TPP1,SULT4A1,CNTNAP2,SPOCK3,DMTF1,SNX29,EDN1,TENM1,RASGRP2,SPEG,CSPG5,OGA,GABRG2,GAD1,GRM8,SOX21,HLF,ICA1,MYCN,PPP5C,MAPK7,PTPRD,RGS4,RGS12,KLHDC8A,STUM,CNKSR2,SP4,UNC5B,ATP10B,KIAA1107,SLC35G2,R3HDM1,TNS1,SPHK2,DNALI1" Drug 4090_UP Myricetin [529-44-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ADGRF5,APC,CDK13,ATP2B2,KSR1,MTMR3,CACNA1G,CFAP410,CACNB4,CAMK2A,RUNX1T1,ENTPD2,CHGB,NRXN3,AKAP6,CABP1,COL9A3,CSF1R,LRIG1,DRP2,HEYL,SRPK3,FAM198B,SIGLEC8,ADAM28,GRM8,LSAMP,MMP16,NNAT,ENPP2,ABCB1,CCDC40,RNASEL,EMID1,KCNIP1,SCN2B,FRMPD1,ASAP3,ST8SIA1,PKNOX2,SNCA,DDN,COBL,SYT5,HIF3A,KCNK12,MKRN3,DNALI1,SLC17A7,KCNAB1" Drug 5795_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "RALGAPA1,NDRG2,LTBP4,AMPH,ANK2,KIF1A,BMP7,CALB2,SPOCK2,ECM2,EDNRB,PLXNC1,EZH1,AGAP2,GATM,NEU3,RAB30,TDRKH,CNTRL,SPACA9,GRIK5,CACFD1,SOX21,IGF1,KCNB1,KCNH2,KHK,KIF5A,MAP2,MSR1,TAGLN3,MYT1,NECAB2,C19orf57,ACSS3,RFX2,TCP11L1,SLC12A4,SNCA,KIF13A,KDM4B,DOK5,RBM26,SSTR2,SYT5,TACR1,PHF24,THRA,VSNL1,KCNAB1" Drug 4064_DN Corticosterone [50-22-6]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "RALGAPA1,TRMT9B,AMH,AMPD3,PPP4R4,ATP2A2,ALDH7A1,SYNJ2,CACNA1I,BAIAP3,CBFA2T2,LHX2,CNTFR,AKAP5,NCOR2,ARHGEF10,DZIP3,GPRASP1,BRINP1,FAM13A,SUGP2,PLXNC1,AASS,IRAK4,MTSS1L,ST3GAL6,FGF1,FGFR1,CINP,SEPT9,GNAL,TDRKH,HSF2,MAPT,MATN3,MGAT3,AFF1,NOVA2,PLCD1,PTPRB,PPP4R3A,IQSEC2,MCF2L,TIAM1,TK2,R3HDM1,VGF,ZNF74,REEP1,HPS4" Drug 3228_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ALK,APBB2,MARK4,ATP1A3,N4BP2L1,NRP2,SYNJ2,CFAP410,CA4,RUNX1T1,CBFA2T2,CHGB,ARHGAP22,COL9A3,BAG4,GREB1,CYBB,DTNB,SEMA3D,NCALD,FAM198B,ZNF589,FGFR1,HLF,HNMT,IL6ST,KCNJ5,SMAD1,GIT1,NPTX1,PCBP3,NTRK2,CDK18,ENPP2,MBOAT7,PPP2R2B,CNNM2,RGS12,CARF,SLC8A1,DOK5,SPTB,ATP10B,TBCEL,CRTC1,AP4E1,TK2,FLRT2,DNALI1,PLSCR4" Drug 5061_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ASPHD1,ASIC1,NME5,APAF1,DDO,CDK10,ATP1A3,SLC4A4,NRP2,WHRN,RCHY1,CREM,RIMS2,FAM131B,INTS1,PLXNC1,LRRC17,MTSS1L,CORO2B,FGFR1,SIGLEC8,GFER,RUNDC3A,PRUNE2,KCNF1,LIFR,LSS,MAPT,MIA2,AFDN,MMP16,CNOT4,NOVA1,OPRL1,PDE4D,PFKFB2,RGS12,SCN2B,CNKSR2,SLC11A1,SNCA,KIF13A,KDM4B,ARHGAP26,SYN2,SYT5,SLC44A1,R3HDM1,KCNK12,SEMA3B" Drug 5540_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "LTBP4,BIN1,CDC42BPA,APC,GAS7,PPFIA3,CDK10,RASL11B,ALDH7A1,MTMR3,KRIT1,SLC16A4,FOXN3,STOML1,SULT4A1,AKAP7,MYRIP,NRG2,CSF1,CSF1R,PDE4DIP,RIMS2,DCAF8,TM9SF4,DAPK3,BRINP1,CHRDL1,MTSS1L,SCML2,DLC1,SRCAP,GPR37,ATXN2L,HNMT,ICA1,JAK2,KCNN1,ADAM22,PLCD1,LRP12,RIPOR1,TCP11L1,MAP6D1,SYBU,KDM4C,WSCD1,TK2,TNS1,EVI5,PHTF2" Drug 4649_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ADD2,ADORA1,PTCH2,SLC2A11,KIF1A,BACH1,KSR1,BAIAP3,CACNA1A,CACNA2D1,CAMK2B,RUNX1T1,SLC16A4,CLTB,VAX2,CNTFR,COL9A3,RCHY1,SPOCK2,ELMO1,EXOG,EDIL3,HEYL,HPCAL4,FLT1,ERAP1,SIGLEC8,GLI2,SMAD9,NOVA2,OGG1,MTRF1L,CNNM2,WDR25,PTPRN,CCDC40,ENOX1,RGS12,GSTCD,SCN2B,MRAS,SH3BP2,SNAP25,IZUMO4,ATP10B,SSTR2,EXOC7,TAL1,DNAH7,TNS1" Drug 3809_DN Ethotoin [86-35-1]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ASPHD1,AMT,ATP1A3,NRP2,SCAPER,MTMR3,CBS,SEPT7,ARHGAP33,AKAP7,AKAP5,EDIL3,HIPK3,CNNM1,ING4,COQ7,NCALD,FGF1,FGFR1,PRELID3A,CNTRL,GRIK5,ICA1,SHISAL1,SCIN,ITPKA,KIFC3,KIT,MAP2,MAPT,GIT1,LYRM9,ZNF862,PIK3R1,RETREG1,ELOVL2,PTPRB,ZCWPW1,FBXW7,RXRA,ST6GAL1,DZIP1,KDM4B,TSNAXIP1,ZEB1,TNS2,TRIO,TSN,VIPR2,XRCC4" Drug 3038_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "PKP4,APBB2,APOC1,AZGP1,NRP2,HIP1R,STOML1,ENTPD4,PDE4DIP,SLITRK5,RUBCN,DOCK4,ZNF337,TM9SF4,FAM13A,MTSS1L,F5,ST3GAL6,CGREF1,ERAP1,INPP5K,GATM,PRRC2B,LILRA2,ATXN2L,ITGAM,LSS,SMAD1,MAP4,CNOT4,SLC25A23,LRP12,DEF8,PTCH1,RAD51D,ZDHHC14,SCN2B,SNCA,SS18,PLCB1,KIAA1107,DMXL2,ZMAT3,TRPS1,FLRT2,LAT2,XRCC4,EMSY,HPS4,PHTF2" Drug 3445_DN Vidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "EPB41L5,NCOA1,BCL7A,ST3GAL5,TAOK2,CLCN3,QKI,BAG4,ARHGEF10,TBC1D5,DAPK3,SGSM2,TOM1,E2F5,FCF1,STX2,GALC,GCNT2,GLYR1,GPD2,GPR37,CNTRL,HNMT,DHX35,IPO5,LSS,MBD1,MIA2,LYRM9,NLE1,ZCWPW1,SAFB,AMBRA1,BTBD7,ZHX3,CDK19,TROVE2,PLCB1,TRIM2,TIAM1,PARD3,UBE3A,PLPPR2,KLC2,XRCC4,ZBTB14,GDPD5,HPS4,SMIM8,PHTF2" Drug 4193_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "NME5,N4BP2L1,NRP2,SCAPER,HAP1,LARGE1,MAGI1,ABCG2,HOMER3,CNTN1,PCYT1B,CNTNAP2,DMD,ING4,TNK2,CORO2B,ZNF589,FGFR1,IQCG,FLT1,PDLIM5,MSTN,PCDH17,TDRKH,GSTM5,LAMA2,SHC3,NF1,NTRK3,ELOVL2,ZSCAN32,ACSS3,SH3TC2,ENOX1,STUM,SUPT20H,DZIP1,ST8SIA1,PREX2,SNCA,RBM34,ZC3H13,TROVE2,RPGRIP1L,CHST8,TK2,TNS1,TUBB1,SLC17A7,FZD3" Drug 4741_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "NDRG2,DOC2A,APLP1,ARHGDIG,PLA2G4C,SYNJ2,SCAPER,CA4,SPAG9,B4GALT6,FAM189A2,QKI,WHRN,ENTPD4,DAPK3,NCALD,BAIAP2,AFF2,GAD1,ERAP1,INPP5K,INPP1,MIA2,MMP16,NF1,NPTX1,PDE4A,RETREG1,NLE1,PRPH,SAMD9,NKAIN1,MAP6D1,SH3BP2,ASAP3,CHD9,SYBU,EPN2,SMARCD3,UHRF1BP1L,KDM4C,CLSTN2,PLCB1,TNS1,RUNDC3B,ZKSCAN5,HIRA,RPRM,FAM155A,EMSY" Drug 6631_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ACHE,ADD1,FZD9,AMPH,SEMA7A,GAS7,CDK10,BMP7,KALRN,HAP1,CAST,FOXN3,TPP1,AKAP5,ENTPD4,RGS6,SV2B,HIPK3,MBNL2,ING4,ELN,FGFR1,GATM,NEU3,PRUNE2,ITPKA,KCNJ5,AFF1,MMP16,FXYD1,MTRF1L,LRRN3,PRKAR1B,PRPH,ELOVL2,PTPRD,TMEM231,RGS4,KCTD17,PNMA8A,ASAP3,SLA,PPP4R3A,DOK5,PHLDB1,TCF4,ICAM5,CDK20,ZNF24,HRASLS" Drug 2514_UP Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "ADD2,AGT,APAF1,CDC14B,BMP7,CA12,HIP1R,ARHGAP33,SOCS6,NRG2,DCAF4,RUSC2,OPTN,ING4,SRPK3,COQ7,FAM198B,ST3GAL6,FER,FHL1,AGAP2,PDLIM5,OGA,ZNF44,SIGLEC8,CSDC2,PCLO,GRIK4,GRM8,GSN,FAM107A,PADI2,KCNN1,MMP16,TAGLN3,NF1,P2RY1,PRKAR1B,PTPN13,MARCH1,KCTD17,SH3BGR,ASAP3,IZUMO4,TAL1,WSCD1,PCDHA5,FAM155A,LMF1,SLC17A7" Drug 6321_DN 2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.20E-08 1.84E-03 6.11E-06 6.88E-05 50 199 "AP2A2,AK2,AMT,APC,APOC1,SEMA4G,IQCK,NCOR2,GPRASP1,GIT2,DCTN1,MFAP3L,RUSC2,SPOCK3,SGSM2,FEM1B,OPTN,EGFR,NCALD,ZNF589,FGF1,FGFR1,TRMO,FAM49B,CGREF1,FYN,DISC1,SRCAP,GLYR1,GNG4,RASSF8,BACH2,SHISAL1,TJAP1,LIFR,MN1,CNNM2,RIPOR1,MAPK12,SBF1,ASAP3,NLGN1,SMARCA4,SMARCC2,SMARCD3,IFT122,THSD1,CEP68,SSBP2,XRCC4" Drug 5733_UP Syrosingopine [84-36-6]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.55E-08 1.99E-03 6.55E-06 7.37E-05 48 188 "ADD2,LTBP4,APAF1,ADGRB2,ST3GAL5,IL33,CALB2,CBS,SYNGR3,ARHGEF2,KCNAB3,ARMC8,AKAP12,AATK,CTH,GIT2,FAM13A,ZNF391,FGFR1,FYN,STON1,GRB10,GRIK5,ELOVL5,JAK2,KIT,TAGLN3,MXI1,NTRK3,PDE4B,PDE4D,STRN3,FA2H,MINDY2,PRPH,PTPRH,SH3BP2,FRMPD1,RBM34,SOX15,ZNF423,SPTAN1,PCDHA6,HEY1,PIK3R5,UBE3A,KCNAB1,SENP7" Drug 7097_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.55E-08 1.99E-03 6.55E-06 7.37E-05 48 188 "RIPK1,CFLAR,CNOT8,ARMC8,WHRN,ABI3BP,HINFP,DCAF4,ZFYVE16,ZNF337,GIT2,KMT5B,EIF5,ETV1,CHST15,TRAF3IP2,INPP5K,FERMT2,GUCY1A1,GUCY1B1,MKLN1,NEK1,NPR2,OGG1,PLCD1,PPP5C,TMEM104,CCDC25,SBF1,ST6GAL1,CCDC88A,TTC17,PDZD2,SS18,CEP68,MTCL1,MGRN1,TRIM2,TK2,KAT6B,ZNF23,TRIM9,NDRG4,ZNF189,CIAPIN1,VPS35L,SMIM8,ACTR3B" Drug 5882_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.55E-08 1.99E-03 6.55E-06 7.37E-05 48 188 "ASPHD1,ADRB2,EPB41L5,PPP4R4,ARNTL,ST3GAL5,BAIAP3,CD86,ARHGAP22,WHRN,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,FYN,STON1,GPR37,TPPP,GUCY1B1,KIFC3,LIFR,MAP2,MAPT,MMP16,PCDH9,SERPINI1,PLCD1,PRPH,TMEM231,ENOX1,RGS4,FBXW7,RPS6KA2,SH3GL3,ASAP3,DZIP1,FAM214B,ARHGAP26,SPTAN1,THSD1,CEP68,RGL1,SYT1,COBL,SSBP2,TRIM9,PLSCR4" Drug CID000000764 guanine Stitch 4.57E-08 2.00E-03 6.55E-06 7.37E-05 156 903 "ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,NME5,AMPD2,AMPD3,OGT,PKP4,APC,MADD,CASK,ARHGDIA,ARRB1,ARRB2,PDE8B,ALDH7A1,ARHGEF25,CCK,P2RX6,ARHGEF1,CD38,LRBA,ARHGEF2,MAGI1,CHN1,NGEF,ARHGEF6,GDA,RGS6,ARHGEF10,RASGEF1C,PLCXD3,GPSM1,DOCK4,ARHGAP24,GIT2,SLC29A4,DOCK2,E2F5,EDN3,EDNRB,RASGRP1,OPTN,RASA4,TUBD1,RASGRP2,RRAGB,GMPR2,TUBB3,POLK,AGAP2,AGAP3,RASL10A,GAA,RAPGEF6,IQGAP2,GATM,TUBA8,DHRS4,POLL,GNAL,GNAO1,GNG4,LPAR4,MCHR1,GRB10,GRIA2,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,RABL2A,GABARAPL2,GIT1,N6AMT1,P2RY13,NCF2,NF1,NFE2L2,NNAT,NME4,NPY,OGG1,OPRL1,P2RX7,P2RY1,GNG2,GPSM2,PLCB2,PLCD1,RASGEF1B,PRKACB,MAPK3,MAPK9,MAPK10,DIRAS2,MASP1,PSMA6,RASGRF1,RASGRF2,RGS4,RGS12,RNASE1,RIC8B,RNH1,FNIP1,MRAS,SUPT20H,RASA3,SHMT2,PREX2,ARFGAP1,ZKSCAN3,NMNAT2,MYCBP2,MCF2L2,SST,SSTR1,SSTR2,RGL1,ARHGEF9,NUDT10,PLCB1,MLST8,MCF2L,EXOC7,TBL1X,DOCK9,SIRT1,TMEM121,TIAM1,TK2,BHLHB9,SMUG1,TRIO,NEIL2,TSC1,TSC2,TUBB2A,TUBB1,UGT8,VAV1,VIPR2,P2RY12,PRTFDC1,TUBA1A,PLD4" Drug ctd:D019422 Dietary Sucrose CTD 4.57E-08 2.00E-03 6.55E-06 7.37E-05 162 946 "NCKAP5,CCDC85A,ADD2,USP31,UNC5A,RNF150,PTCHD1,LRFN2,BBOX1,ARMC12,PPFIA4,CPNE5,DNAH17,ATP6V1G2,BARD1,HCN2,CACNA1G,CA4,KALRN,HAP1,CAMK2A,CAMK2B,CH25H,P2RX6,DGKI,SLIT2,RAB33A,SULT4A1,IGLON5,CNR1,COL11A2,NRG2,FAM171B,CRHBP,HAPLN1,CRYBB1,AATK,CSF1R,RIMS4,CST3,FAM131B,DBI,GSDME,GRIN3A,HS3ST2,SHANK1,SLC25A18,EBF1,RGS17,SRPK3,HSD17B14,ENPP6,NCALD,APC2,TMEM132C,ACSL4,PPP1R1B,OLFM1,FGF11,SCARA3,PSD2,EFCAB2,SPECC1,TRIM16,PRELID3A,DLL3,GABBR1,MTHFD2,GCK,GDF9,GPR162,CYP46A1,PCDH17,PPARGC1A,GLI2,RAB30,AIFM3,GNAO1,LILRB4,STON1,STMN2,PLCD4,SERP2,PTPRT,RNF165,HAS2,IGFBPL1,CELF5,IGF1,LRRC25,NIM1K,ITPKB,CDH20,KCNF1,KCNQ3,KPNA5,SYTL4,SCAMP5,MMP17,MPP2,HS6ST3,MYH3,MYT1,NEFM,NFE2L2,NINJ2,NPY,NPTX2,NRCAM,NTRK2,OXTR,PCDH8,PDE1B,SLC10A4,PFKFB3,PFKFB4,PGAM2,PLIN1,EPB41L4B,PPARA,MAPK4,LAMA1,GDPD2,TMEM104,MARCH1,FAT4,PNMA8A,GALNT10,SHC4,CCDC92,ST8SIA1,ANKRD6,PEX26,SLC6A11,KDM4D,SLC8A1,RADIL,BTBD7,LGI3,FAIM2,NFASC,SYP,MCF2L,ADGRL3,PCDHB9,PCDHB4,HIF3A,SIRT1,CHST8,GPR161,HEY1,TIMP4,PRRT1,FAM155A,OSBP2,TSPAN11,RBFOX3,KCNK12,ZIC2,TRIM9,PRRT4,SPATA13" Drug 3880_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.78E-08 2.09E-03 6.78E-06 7.64E-05 49 194 "NDRG2,ADORA1,ADORA2A,ALCAM,FAM135A,EPB41L5,GYG2,CACNA1I,LDLRAD4,CAMK2B,RHBDL1,CNTN1,FAM149A,CPS1,TMCC2,HS3ST2,EGR3,ELN,SPEG,FGFR1,ANKFY1,KHDRBS3,DISC1,GFER,GRIK5,ITPKA,JAK2,KIT,MAPT,KITLG,ADAM22,NELL2,CLDN11,PCDH9,MINDY2,SNRK,S100B,SLC4A3,SLC11A1,HECW1,ATP10B,ARC,TBCEL,TIMP4,HIRA,UBE3A,EMSY,SLC17A7,KCNAB1" Drug 5836_UP Streptozotocin [18883-66-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.78E-08 2.09E-03 6.78E-06 7.64E-05 49 194 "BIN1,APBB2,LGR5,SEMA4G,CFLAR,ST3GAL5,SCAPER,CACNA1I,C5,CNOT8,ABCG2,QKI,CNTNAP2,ZNF337,DAPK3,MYEF2,FAM13A,ETV1,FCGRT,ZNF589,SEMA4D,TRMO,FYB1,ERAP1,SRCAP,MAN2A2,MAPT,ADAM22,TAGLN3,LYRM9,ZNF426,PPARA,BCAS3,APTX,PTCH1,BEND5,TCP11L1,RXRA,SUPT20H,KBTBD4,TMCC1,IQSEC2,STX1A,THRA,HIRA,WIPF1,EVI5,KCNAB1,RNF146" Drug 2825_UP Probenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.78E-08 2.09E-03 6.78E-06 7.64E-05 49 194 "ADCY6,AP2A2,NME5,C1QTNF3,SEMA6A,AMT,KCNAB2,APBB2,APC,CDC14B,MARK4,CFLAR,GYG2,LDLRAD4,SYNGR3,RCBTB2,FOXN3,SOCS6,CTH,EXOG,HIPK3,MBNL2,TNK2,EZH1,FGF13,AFF2,MSL3,GPER1,SPACA9,GSN,IRF8,MEIS2,MID1,MITF,ADAM22,NNAT,PCDH9,MAPK10,VPS13C,ASAP3,SNCA,SP4,ZBTB43,PCDHA6,UCHL1,PLPPR2,GDPD5,UBE3B,ADAMTSL3" Drug 4954_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.84E-08 2.12E-03 6.79E-06 7.65E-05 46 177 "NME5,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,TMCC2,OPTN,FAM13A,RASGRP2,STX2,FYN,CYP46A1,RAB40B,STON1,MAP2,MXI1,NEK1,PCDH9,SERPINI1,PRPH,PTCH1,RPS6KA2,SH3GL3,WDR47,PKNOX2,ARHGEF40,ZBTB43,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SLC30A3,SLC17A7,ITM2C,PLSCR4" Drug 5745_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.84E-08 2.12E-03 6.79E-06 7.65E-05 46 177 "ADRB2,ARNTL,MARK4,ADGRB2,ST3GAL5,HAP1,USP2,SYNGR3,NRXN3,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,IGSF6,TAOK3,FGFR1,BAIAP2,FYN,STON1,FAM69A,ITGA7,MAPT,MMP16,TAGLN3,PCDH9,SERPINI1,PRPH,RGS4,SH3GL3,KDM4B,SOX15,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,COBL,MCF2L,OBSL1,SSBP2,TRIM9,SLC30A3,SLC17A7,PLSCR4" Drug 5945_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.84E-08 2.12E-03 6.79E-06 7.65E-05 46 177 "ADRB2,NME5,BIN1,MARK4,BMP7,BAIAP3,SPAG9,CLGN,WHRN,PDE4DIP,CTH,SEC14L5,ARMCX2,OPTN,FAM13A,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MMP17,PCDH9,ENPP2,SERPINI1,PLCD1,PRPH,RPS6KA2,SMPD3,SH3GL3,ASAP3,WDR47,PKNOX2,PEG10,SPTAN1,ELOVL4,RGL1,STX1A,STXBP1,ZEB1,HEY1,RUNDC3B,SSBP2,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug ctd:D004237 Diuron CTD 4.88E-08 2.14E-03 6.79E-06 7.65E-05 269 1742 "ACHE,SYS1,ACTN1,TMEM132B,GALNT16,ADCY6,TMCC3,AP2A2,KLHL13,AGT,SPARCL1,ALCAM,SRPX,CEP126,ARHGAP20,LTBP4,GPRASP2,AMT,ANK2,PI16,PKP4,APBB2,MARCH3,NCOA1,DYNLL1,ATP1B3,ATP2A2,DOCK11,SEC11C,CFLAR,PROM1,SCAPER,MTMR2,IL33,CA8,CA12,CALM1,HAP1,CAST,SPAG9,ARHGEF25,CBR1,CD86,SCARB1,ENTPD2,DCLK1,LRRFIP1,CDO1,CCPG1,CLGN,CFL2,FOXN3,PLEKHB1,MS4A7,B4GALT6,MYL6B,FAM189A2,QKI,CNN3,ARHGEF6,COL11A2,ABI3BP,ZNF521,NECTIN3,FAM171B,C2CD2,RBM39,AKAP12,GDA,VCAN,CST3,DZIP3,RIPOR2,ARHGAP24,SCRN1,SPOCK2,BRINP1,DBN1,YTHDC1,C2CD2L,ZC3H11A,DMPK,CPEB2,DPYSL2,DTNB,ECM2,ABCC5,FIS1,EBF1,FEM1B,EEF1D,FRY,EIF4G1,CERCAM,PCOLCE2,EIF1,ENO2,EPB41L2,LRRC17,RASGRP2,SRRM1,NCALD,MRVI1,EZH1,FAM198B,ACSL4,TAOK3,STRADA,FGF1,FGFR1,AMOTL2,FHL1,MEX3B,FLT1,FOLR2,PDLIM5,RASL10A,ERGIC3,ST6GALNAC3,SARAF,TPPP3,MPP6,FYB1,FYN,RAPGEF6,ACSS1,GCNT2,SESN1,GHR,LYVE1,DHRS4,TCERG1,TOX3,GLUL,HTATSF1,KCNMB4,LOXL3,FERMT2,GPD1,GRB10,PLCD4,GSN,GSTM5,GUCY1A1,IRAK3,HAS2,CPT1C,MSL1,SOWAHA,IGF1,IL6ST,ITGA7,KLHL23,KIFC3,KTN1,LAMA2,PIK3AP1,MAP2,MATN2,MATN3,KITLG,MITF,AFDN,MMP16,DBNL,COMMD5,NBL1,NFE2L2,NFIX,NNAT,NPR2,PCBP3,NTRK2,CLDN11,PCSK5,ENPP2,TMOD2,CYTL1,SERPINI1,PIK3R1,RETREG1,PKM,GPSM2,FXYD1,PLTP,PLXNB1,PMP22,MINDY2,PPP1R1A,PPP2R2B,NKAIN4,PRKACB,PRKCB,GRAMD1C,VPS13C,DEF8,GDPD2,PTPRO,ROGDI,RBBP6,RDX,PBRM1,SETD5,EMID1,RPS20,HUNK,CLIP1,RTN1,S100B,SCP2,SMPD3,SEC14L1,SGK1,SH3BGR,SHMT2,ST6GAL1,ANKRD6,LIMS2,ARHGEF40,SLC12A2,SLC12A4,SLC14A1,CPEB4,KIF13A,LMBRD1,KDM4C,ZC3H13,KANK1,PRRC2C,COBL,TACC1,TBL1X,DMXL2,ZEB1,TRIM2,SLC35G2,PCDHA1,TEK,ITGB3BP,ZNF106,CDH22,SLC44A1,TMPO,PRRT1,TNS1,TPM1,TPM2,SYNPO2,TTC3,TUBB2A,RPRM,UCHL1,GORASP1,VLDLR,RBFOX3,P2RY12,PCDH20,AGMO,TUBA1A,ADAMTS9,PDSS2,HRASLS,MARCH8,KAT6A,HNRNPA3,PHTF2,ACTR3B,JMJD1C,MSRB3" Drug 4579_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "ADD2,ADRA1D,AP2A2,SEMA7A,APBB2,AZGP1,CACNA1I,LDLRAD4,ARHGEF2,CRLF1,CBARP,EPS15L1,AKAP6,CREM,PDE4DIP,ARHGEF4,USP6NL,ING4,COQ7,REEP2,LILRB4,GPD2,CNTRL,CACFD1,GRM8,GUCY1B1,ICA1,ITGA7,KCNF1,LIG4,MEF2C,TAGLN3,CNOT4,NPY,PDE4D,PFKFB4,LRRN3,PRKAR1B,MAPK10,ZNF821,HECW1,THSD1,TBCEL,TRIM2,TK2,TPM1,CHST5,ZNF24,ZNF225,PARP11" Drug 2265_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "ADGRF5,PRX,CDK13,ATP2B2,ADGRB1,CACNA1I,CFAP410,RUNX1T1,USP2,CDO1,DLGAP1,CNR1,CRMP1,CSF1,SPOCK2,EXOG,ELN,VPS13B,RASGRP2,NCALD,OGA,GAD1,SEPT9,GNAO1,IRAK3,KCNJ5,MATN3,MEF2C,MMP16,MSR1,MX1,MYCN,NNAT,PDE4B,PFKFB2,GDPD2,PTCH1,CCDC40,GAL3ST4,RNASEL,ASAP3,FNDC3A,COA1,CDK19,SSTR1,JMJD6,EXOC7,HIF3A,PIK3R5,KAT6A" Drug 4481_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "ADRA1D,ALK,APAF1,ATP1A3,CACNA1I,CFAP410,CALB2,CD86,CNTFR,COL9A3,CSF1,BRINP1,MFAP3L,EXOG,DRP2,SEMA3D,F5,DLC1,FGFR1,FAM49B,ZNF44,KCNF1,MMP17,NCAM2,NELL2,CDK18,DUSP26,RETREG1,PLXNB1,ZSCAN2,NKAIN1,KCTD17,ZNF671,MRAS,SH3BP2,FRMPD1,DZIP1,SLA,SLC12A4,ZHX3,HECW1,SPTB,ASTN2,TACR1,MCF2L,KLHL4,DOCK9,ZFPM2,REEP1,EPM2A" Drug 3833_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "NDRG2,APBB2,RGS20,ATP2B2,RGS11,GYG2,CACNA1I,BAIAP3,USP2,SLC16A4,CBFA2T2,CDO1,CLGN,QKI,SNCAIP,CSF1,PHF14,RASSF2,TMCC2,ERCC2,FGF13,FGFR1,AGAP2,PDLIM5,CAMKK2,SRCAP,RUNDC3A,IRF8,TJAP1,JAK2,KCNJ5,MMP16,ADAM22,NF1,TMOD2,NKAIN1,PID1,ZNF493,KCNIP1,CPEB3,FBXO11,SLC2A5,SLC11A1,RBM34,HECW1,ZC3H13,ARC,SZT2,SPHK2,EMSY" Drug 5502_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "ABHD6,ALK,APC,GAS7,CDC14B,HAP1,CBFA2T2,SULT4A1,RCHY1,MED12,HIPK3,STX2,ERCC2,EZH1,ACSL4,FECH,FGF13,AGAP2,PRELID3A,GABRG2,GPD2,PCLO,CNTRL,HNMT,SHISAL1,INPP5B,LIG4,AFF1,ADAM22,MYCN,NFYA,GPR85,STRN3,PPP2R2B,PRKAR1B,PTCH1,RPS6KA2,SH3GL3,SLC2A5,PEX26,TROVE2,NXT2,ASTN2,EXOC7,DMXL2,RPGRIP1L,LMF1,CLIP2,XRCC4,PCBP4" Drug 3698_DN Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "C1QTNF3,AMPD3,APAF1,KIF1A,SCAPER,BAIAP3,CAMK2B,CBS,SEPT7,LARGE1,B4GALT6,TAOK2,PLAA,CNTFR,AKAP7,HAPLN1,CNTNAP2,SLITRK5,ARMCX2,DMPK,DTNA,PLXNC1,CORO2B,FGFR1,PCDH17,SPACA9,KHK,MAN2A2,GIT1,NF1,PRKAR1B,PRPH,CNNM2,PTPRB,GAL3ST4,CSRNP3,SCN8A,ZNF821,MRAS,ASAP3,DZIP1,PREX2,PKNOX2,ARHGEF40,SNCA,ARHGAP26,MCF2L,LMF1,LAT2,WNT7A" Drug 6688_DN Debrisoquin sulfate [581-88-4]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "CDC42BPA,DNAH17,MARK4,KIF1A,ST3GAL5,STOML1,ABCG2,CSF1R,CSNK1E,BRINP1,CHRDL1,MTSS1L,AFF2,TRMO,OGA,FYB1,GAD1,GFER,GNG4,TDRKH,SHISAL1,SCIN,MGAT3,AFF1,MMP16,CLDN11,PDE4A,PIK3R1,PPARA,GRAMD1C,PTN,C1orf54,KIRREL1,ASAP3,PEX26,RBM34,UNC5B,DDN,ATP10B,TROVE2,PLCB1,MCF2L,ADGRL3,TK2,TNS1,TPM2,WIPF1,KLC2,KCNAB1,EPM2A" Drug 7463_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "SEMA6A,DOC2A,NCOA1,N4BP2L1,BCL7A,CFAP410,HAP1,CBFA2T2,CLTB,SULT4A1,NCOR2,GPRASP1,TBC1D5,E2F5,OPTN,EIF5,MRNIP,ELN,SRCAP,MALT1,COPS8,GRB10,RNFT2,INPP5B,MAP4,MIA2,KITLG,GIT1,NF1,PLXNB1,PRKAR1B,WDR25,PTN,ZSCAN32,RIPOR1,RGS12,KANSL3,SLC11A1,SNCA,HECW1,TROVE2,MCF2L,WSCD1,TRIM2,TIAM1,TK2,R3HDM1,PIK3R5,KCNK12,TFIP11" Drug 3735_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.99E-08 2.19E-03 6.79E-06 7.65E-05 50 200 "ASPHD1,ADRA1D,APAF1,DNAH17,N4BP2L1,ATP6V0A1,NRP2,BMP7,FUBP1,CFAP410,CDO1,RAB28,IQCK,ABCG1,LRIG1,PDE4DIP,EXOG,RCAN1,OLFM1,BAIAP2,FYB1,ALDH1L1,SRCAP,ADAM28,RUNDC3A,GPD2,MAP4K5,KCNJ5,LAMA2,MMP16,NDP,NFYA,PDE4B,PDE4D,RGS4,PNMA8A,SUPT20H,FNDC3A,CNKSR2,ARHGEF40,HECW1,PLCB1,ASTN2,ADGRL3,TNS1,UCHL1,PDIA2,LAT2,ZNF24,KCNAB1" Drug ctd:D007657 Ketone Bodies CTD 5.02E-08 2.20E-03 6.81E-06 7.67E-05 101 522 "ACADM,AP2A2,PKP4,APLP1,SPTBN4,ZBTB10,NCOA1,ATP1A1,ATP2A2,ATP6V0A1,BMP7,CAMK2A,CAMK2B,CARS,ARHGEF25,CERS5,MTMR7,SYNGR3,PLAA,CLCN3,CLTC,FBXO7,CNN3,MAGED1,MYRIP,AKAP12,CRMP1,CRY2,DNM1,DNM1L,FIS1,EDNRA,ANKRD46,KCTD3,EIF5,MRNIP,FDFT1,FGF14,ATP5PD,EVL,FAM49B,ACSS1,CPLX2,RNPS1,ZNF638,FERMT2,GRIA2,GRIK4,KAT7,PADI2,ELOVL5,ACOT7,CELF5,KCNN2,STXBP5,MAP4,MBP,PTOV1,NPTX1,OPRL1,P2RX7,OLA1,SERPINI1,PLCD1,LRP12,SCHIP1,SEPT4,POLR2F,PPP1R1A,PPP2R2B,PPP3CA,PKIA,PSD,PTPRN2,ZNF354C,STX1B,SARS,SCP2,KBTBD4,CDK5RAP2,MYCBP2,CLASP2,JMJD6,SUPT5H,SYT5,TCF4,PUM2,RIMBP2,R3HDM1,CABIN1,TP53BP1,RPL7L1,UCHL1,MTCH1,VSNL1,CLDND1,ATP6V0E2,TMEM178A,RTN4,HNRNPA3,RNF146" Drug 2283_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "RALGAPA1,ADRA1D,APBB2,GAS7,ARRB2,ALDH7A1,CFLAR,LHX2,QKI,ABCG1,GREB1,RIMS2,RCAN1,CELSR3,EGFR,VPS26C,ANKFY1,GCNT2,SRCAP,GPD2,GRIK5,ITPKB,LSS,MAP4,KITLG,MSI1,ADAM22,ZNF862,NF1,PLCD1,STRN3,POLG,MINDY2,PRODH,KLHDC8A,GSTCD,SH3BP2,PREX2,PEX26,PPP4R3A,TSNAXIP1,POGZ,SS18,ELOVL4,PLCB1,PCDHA6,TMPO,CDK20,ZKSCAN5" Drug 983_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "ALCAM,PPFIA3,CDK13,SCAPER,SLC16A4,ARHGEF2,CLGN,COL9A3,CSNK1E,DCAF8,JAKMIP2,DTNA,EGR3,VPS26C,FHL1,PDLIM5,DLL3,GLYR1,BTN2A1,HLF,ICA1,IL6ST,INPP5B,LSS,MGAT3,AFDN,MMP16,MPP2,ADAM22,CNOT4,PLTP,MINDY2,PPP5C,MAPK7,CEP97,GSTCD,EMID1,SLC22A4,LIMCH1,SNCA,KIF13A,TSPYL2,RGL1,STX1A,TRIM2,OSBP2,VGF,VLDLR,PHTF2" Drug 5576_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "ADD2,ADORA2A,C1QTNF1,ABCD2,APC,PRX,ATP2B2,AZGP1,LDLRAD4,USP2,WHRN,SNPH,SPOCK2,GSDME,SNX29,EDNRB,ING4,CORO2B,FGF1,OGA,PRUNE2,ADAMTS13,GRIK5,ICA1,KCNJ5,MGAT3,MMP16,MYCN,P2RY13,PAX6,GPR85,PFKFB4,MTRF1L,PRKCB,MAPK7,SAMD9,RFX2,SCN8A,SNCA,HECW1,ZNF423,ZC3H13,SPTB,SYN2,SZT2,GPR161,TPM2,FLRT2,SLC17A7" Drug 6699_DN Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "RALGAPA1,APBB2,APC,PDE8B,KIF1A,NRP2,ST3GAL5,MYRF,ARHGEF1,NRXN3,IQCK,BAG4,NCOR2,RUSC2,SPOCK3,CNNM1,EGFR,COQ7,MTSS1L,ZNF589,B4GALNT1,SYT17,GFER,TDRKH,LPAR4,SCIN,IL6ST,FAM69A,SCAMP5,GRAMD1C,PTN,TMEM231,FAT4,RGS3,ASAP3,SLC4A3,IQSEC2,DDN,MCF2L,KIAA1107,TCF4,DNAH7,THRA,TK2,TPM2,XRCC4,KCNAB1,TIGD6,DPF3" Drug 7468_UP Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "ASPHD1,ASIC1,SEMA6A,BIN1,RGS20,N4BP2L1,BMP7,CACNA1I,CAMK2G,USP2,FOXN3,AKAP7,HDAC9,TBC1D5,MFAP3L,TMCC2,DNM1,SUGP2,EGFR,F5,PTK2B,ERAP1,INPP5K,TDRKH,GPR37,IL6R,KCNN1,MAP4,MATK,AFF1,ADAM22,NF1,NOVA2,NPTX1,RETREG1,PLXNB1,RIPOR1,SH3BP2,SH3GL3,KDM4C,IQSEC2,TSPYL2,STX1A,PLCB1,PCDHA5,TIAM1,R3HDM1,VAV1,SEMA3B" Drug 3513_DN Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "ASPHD1,AP2A2,BEGAIN,AMT,PLA2G4C,MARK4,NCOA1,CFAP410,CAMK2G,PLAA,ABCG1,CSF1,GREB1,RUSC2,EIF5,NCALD,SCML2,ZNF589,SCARA3,FLNC,OGA,B4GALNT1,HNMT,INPP1,JAK2,IPO5,LYRM9,NFYA,PALM,PRKAR1B,PRODH,WDR25,RGS3,RGS12,PEX26,FAM214B,BTBD7,CDK5RAP2,RBM34,PHLDB1,EXOC7,SATB2,TMEM121,SLC44A1,TK2,PARD3,CABIN1,UBTF,WIPF1" Drug 7469_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.69E-08 2.49E-03 7.55E-06 8.51E-05 49 195 "ADCY6,ADORA1,SEMA6A,ALCAM,BIN1,ARHGDIG,PDE8B,SLC4A4,SYNJ2,SCAPER,BAIAP3,CAMK2G,CD86,CRLF1,FOXN3,NECTIN3,CREM,NCOR2,CSF1,CTH,ARMCX2,CDON,DUSP9,RGS17,VPS26C,FLNC,ERAP1,INPP5K,USP19,TXNL4A,RAB30,IL6R,MIA2,MMP16,MYT1,PALM,PPP2R2B,PRKAR1B,PTN,CCDC25,TCP11L1,RPS6KA2,EMID1,MAPK12,ZHX3,XRCC4,ZNF32,TFIP11,UBE3B" Drug 2403_UP Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.09E-08 2.67E-03 8.06E-06 9.08E-05 44 167 "GAS7,ARRB2,DNAH17,CFLAR,ST3GAL5,CD86,CD38,RCBTB2,CHN2,TPP1,CREM,SIPA1L1,PPP1R16B,DOCK4,FAM13A,PIPOX,PRKAG2,TRAF3IP2,STON1,NCF2,PDE4B,PDE4D,SMOX,MINDY2,SEC14L1,SGK1,SLA,FAM214B,ARHGEF40,ZSWIM8,SPTAN1,CDK19,SS18,STX1A,ARHGEF9,PLCB1,DNMBP,PDLIM2,KIAA1107,TBL1X,FLRT2,CLIP2,ZBTB38,MAP3K12" Drug ctd:D013759 Dronabinol CTD 6.59E-08 2.89E-03 8.44E-06 9.50E-05 156 908 "TMCC3,ADORA2A,HECW2,CASKIN1,KCTD16,TAOK1,SPARCL1,ALCAM,ALK,BCAS1,SHROOM2,CDC14B,SPTBN4,ARHGDIA,ASGR1,ASPA,KIF1A,IL33,CA8,CALB1,CALB2,HAP1,CAMK2A,CAMK2B,CARS,HIP1R,SPAG9,CBLN1,CCK,RGN,LRRFIP1,UBE2L6,COPB2,FOXN3,PLEKHB1,CPNE6,NRXN3,MYL6B,LY86,CNR1,CRMP1,AATK,FAM169A,CENPL,SEC16A,USP3,NR1D2,WDPCP,EDNRA,PHF20L1,EGR3,EIF4G1,EIF5,COPS4,DCTN4,ERBB4,SPEG,NRN1,ACSL4,FGF1,OLFM1,HPCAL4,NSG1,FYN,GABRG2,GALC,MTHFD2,GCK,GCNT2,SESN1,CSDC2,CBX1,DCLK2,GNAO1,GPT2,PLCD4,FAM107A,GUCY1A1,SLC2A6,NXPH3,HP,HSPA1L,SOWAHA,IGF1,IL12A,ITPKA,L1CAM,LIG4,MAP2,MAP6,MAT2A,MBP,TAGLN3,MYH3,FXYD7,NEFH,SLC11A2,NTRK2,NUCB2,OPRL1,CLDN11,ABCB1,PKM,FA2H,PPARA,MAPK3,MAPK9,KLK6,CNNM2,VPS13C,LAMA1,PTN,PTPRE,PTPRN,RASGRF1,CRTAC1,SLC25A36,YY1AP1,KCNIP3,RXRA,S100B,SARS,SCN8A,FNIP1,PUF60,SGK1,SHMT2,SEC31A,ABLIM3,NAPB,CPEB4,MAST1,FAM126B,SOX15,ZC3H13,CDK19,SEPT8,PHLDB1,PRRC2C,ARC,ANKRD12,DNMBP,PDLIM2,SYNE1,PCDHA1,DNAH7,TTC3,PRR18,UBC,UGT8,CCDC136,ZIC1,NDRG4,TFIP11,RTN4,GJC2" Drug 5878_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "APC,CDC14B,ARNTL,CFAP410,KALRN,CBFA2T2,SOCS6,ASIC3,TPP1,MFAP3L,TUBD1,LRRC17,ZNF589,IQCG,SEPT9,GPR75,POLL,TDRKH,GPR37,IL12A,INPP5B,AFDN,ADAM22,MT1M,PLCD1,MAPK7,MAPK10,KLK6,CNNM2,CNTLN,ZSCAN32,ZSCAN2,TMEM231,GAL3ST4,TCP11L1,DZIP1,ZNF667,NMNAT2,ARHGAP26,CLASP2,SAMSN1,COBL,SMG6,TCF4,LMF1,WIPF1,KLC2,REEP1,KCNAB1" Drug 4347_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "LTBP4,KCNAB2,GAS7,MARK4,PTCH2,KSR1,MYRF,CFAP410,CACNA2D1,RUNX1T1,SEPT7,TPP1,SULT4A1,WHRN,ARHGEF4,RIPOR2,SPOCK2,ELN,RASGRP2,FHL1,DLL3,FYB1,PRUNE2,IRF8,ITGA7,KCNB1,KCNH2,KCNJ5,KCNN1,ADAM22,TAGLN3,NOVA2,PALM,PAX6,GPR85,PLCD1,PLTP,MTRF1L,PTPRO,KCNIP1,ZNF821,SLC2A5,KDM4B,ZNF423,ZC3H13,TACR1,SYNE1,HEY1,LAT2" Drug 7346_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ADRA1D,APBB2,RASL11B,ATP2A2,CFLAR,SCAPER,ARHGEF2,B4GALT6,LHX2,LY86,BAG4,PDE4DIP,ARHGEF4,DOCK4,TBC1D5,ARMCX2,PARD6A,EXOG,EGFR,ING4,COQ7,ERCC2,FER,FGFR3,KHDRBS3,SRCAP,RAB30,CACFD1,RASSF8,ATXN2L,HSF2,INPP1,IPO5,MAP4,MAPT,NF1,SMIM7,LRP12,MAPK7,PRODH,PRPH,CNNM2,RIPOR1,GTDC1,ROBO1,SBF1,ZNF821,SYBU,SIN3B" Drug 3375_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ADCY6,AMPH,BIN1,OGT,KCNAB2,GAS7,CBFA2T2,SLIT2,TPP1,SULT4A1,NCOR2,SNCAIP,SEC14L5,DAPK3,ERCC2,PTK2B,FHL1,DLL3,FYB1,SRCAP,ADAM28,CSDC2,RUNDC3A,GPER1,PCLO,GRIK5,GSTM5,KCNN1,MEF2C,MX1,NELL2,NPR2,PPP5C,CEP41,PRODH,FAT4,RPS6KA2,SH3BP2,SH3GL3,ARHGEF40,SLC11A1,PEG10,ARC,ZEB1,DICER1,TNS1,VLDLR,ADAMTS9,EPM2A" Drug 7333_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "AP2A2,CDC42BPA,APBB2,APOC1,PPFIA3,EIF4G3,MTMR2,ARHGEF1,UBE2L6,PLEKHB1,STOML1,DBN1,TSPAN5,GALC,SEPT9,AHDC1,GRB10,KCNF1,MAN2A2,MAP4,MATK,GIT1,ZNF862,PDE4A,PLEC,LRP12,PRKAR1B,CEP97,RAD51D,DPF2,RNASEL,GSTCD,TRAPPC13,SH3BGR,AMBRA1,ANKRD6,ZHX3,TSPYL2,STX1A,TIAM1,ZNF24,ZBTB38,MAP3K12,EMSY,DNALI1,MARCH8,UBE3B,SMIM8,PHTF2" Drug 5800_UP Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "NME5,ATP1A3,ATP6V0A1,BMP7,SCAPER,MTMR3,HAP1,SCARB1,LARGE1,CRLF1,STOML1,HOMER3,AKAP5,ENTPD4,GPRASP1,ARMCX2,DRP2,MBNL2,PLXNC1,EZH1,FGF1,NEU3,POLL,GSN,ELOVL5,ITGA7,MAPT,SLC11A2,NRCAM,PDE4D,TMOD2,VPS13C,PTN,PTPRB,NKAIN1,ACSS3,STUM,RASA3,HKDC1,KANSL3,DOK5,HECW1,SPP1,ZBTB43,SYP,TEK,FLRT2,KCNAB1,NLRP3" Drug 4368_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ABHD6,ADRA1D,AMT,APBB2,APC,ARNTL,CFAP410,SCARB1,CLGN,STOML1,PICK1,CNTFR,AKAP12,ABCG1,CSF1R,DBN1,RUSC2,ERCC2,FGF13,SCARA3,AGAP2,GCNT2,GPD2,STON1,GPR37,GSN,HNMT,KCNH2,LMO2,MMP16,NF1,CNOT4,GRAMD1C,SUPT20H,SH3BP2,SMARCD3,IFT122,KIF13A,KDM4C,IQSEC2,CLSTN2,PHLDB1,STX1A,PLCB1,KIAA1107,TRIM2,FLRT2,SPHK2,KAT6A" Drug 5849_UP Glibenclamide [10238-21-8]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "PKP4,APC,DDO,PPFIA3,ATP1A3,SYNJ1,ST3GAL5,SCAPER,CACNA1A,RAB28,VAX2,HAPLN1,CSF1R,PDE4DIP,CNTNAP2,GPRASP1,SPOCK2,SV2B,DTNA,EGFR,DENND4A,ZNF589,TMEM8B,IL12A,KCNF1,KHK,AFDN,NTRK2,PPP2R2B,MAPK7,GRAMD1C,MASP1,C1orf54,RGS12,TCP11L1,KCNIP1,ASAP3,FNDC3A,ZNF667,IFT122,TMCC1,THSD1,MCF2L,PCDHGA10,TIAM1,RUNDC3B,REEP1,KCNAB1,TIGD6" Drug 3783_DN Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ALK,CDC42BPA,PPP4R4,ADGRB2,BAIAP3,HAP1,ABCG2,RAB26,CPS1,DCAF4,DMPK,HIPK3,CELSR3,TNK2,ETV1,F5,HPCAL4,CGREF1,SIGLEC8,SRCAP,GSTM5,ICA1,TJAP1,INPP5B,KCNJ5,LSS,TAGLN3,NELL2,NF1,NPR2,NTRK2,NLE1,PPARA,PRPH,SNRK,RIPOR1,ACSS3,SUSD4,RFX2,RGS4,NEK11,FAM214B,ZNF334,OGDHL,DDN,TBCEL,TNS1,VGF,LAT2" Drug 4151_DN Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ADORA2A,LTBP4,ALK,APBB2,ALDH7A1,SYNJ1,CFAP410,CAMK2B,ARHGEF2,ASIC3,CLTB,LY86,CNTFR,WHRN,CREM,DCAF8,MBNL2,OLFM1,FHL1,GAD1,SEPT9,ALDH1L1,GPER1,GSN,INPP5B,KCNJ5,MAPT,ADAM22,MX1,MYT1,NF1,NPTX1,P2RY1,PDE1C,PRKCB,KCNIP1,SH3GL3,PREX2,ARC,SYT5,TBCEL,CRTC1,THRA,TPM2,TRPM2,FAM155A,UCHL1,VIPR2,PLSCR4" Drug 4424_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ASIC1,ADCY6,C1QTNF1,SEMA6A,CDC14B,SEMA4G,ARHGDIG,RASL11B,CACNA1I,BAIAP3,CFAP410,CALB2,RUNX1T1,SLC16A4,CHRNA4,CRMP1,NCOR2,CNTNAP2,PIPOX,ST3GAL6,SCARA3,FYN,GSN,JAK2,KIFC3,AFDN,ADAM22,MX1,MYO7A,PCDH8,PDE1C,ENPP2,C19orf57,CEP41,GDPD2,PTPRN,KCTD17,RPS6KA2,SH3GL3,SLC4A3,LIMS2,OGDHL,PEG10,TROVE2,KIAA1107,SYNE1,UBE3A,XRCC4,SLC30A3" Drug 4473_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ARRB1,ATP1A3,NRP2,CACNA1G,CD86,TAOK2,EPS15L1,CNTFR,WHRN,NCOR2,CSF1,PDE4DIP,MAML1,MFAP3L,MBNL2,PLXNC1,ZNF391,REEP2,OLFM1,FYB1,FYN,ADAM28,GLI2,GRM8,KCNF1,ADAM22,MT1M,NTRK2,PDE4B,ENPP2,GPR85,MAPK7,PTPRH,FAT4,KHDRBS2,SUGCT,TCP11L1,KCNIP1,MRAS,CNKSR2,NLGN1,ZNF334,TSNAXIP1,ZHX3,TK2,TNS1,CDK20,VIPR2,KAT6A" Drug 3971_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "NDRG2,LTBP4,AMPD3,KCNAB2,FAM131A,PPP4R4,MARK4,MTMR2,CA12,CAMK2B,SLC16A4,CPS1,SH2B1,CSF1,DZIP3,DOCK4,DCAF8,MAML1,MFAP3L,DUSP9,ZNF589,OGA,GAD1,TXNL4A,GPR37,GRIK5,KCNF1,KCNH2,KCNN2,AFF1,ADAM22,ZNF862,NF1,CNOT4,NPTX1,CLDN11,MINDY2,PRKAR1B,TCP11L1,PEG10,TROVE2,PLCB1,ZNF34,TK2,HIRA,FAM155A,WIPF1,KCNK12,SENP7" Drug 6670_DN Brinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "TRMT9B,AMPD3,GAS7,MYRF,ARHGAP33,SOCS6,NRXN3,IQCK,ABCG1,CSF1R,CSNK1E,CNTNAP2,SLITRK5,ARHGEF4,FEM1B,CELSR3,PLXNC1,MTSS1L,ERCC2,ZNF391,ETV1,BAIAP2,FAM49B,ZNF44,GAD1,B4GALNT1,ERAP1,HLF,LSS,MAPT,MEIS1,N6AMT1,NF1,CNOT4,PLXNB1,MAPK7,PTN,ZCWPW1,NEK11,ZNF671,SCN8A,PPP4R3A,TBCEL,SLC44A1,TIAM1,VIPR2,SEMA3B,PHTF2,TIGD6" Drug 5097_UP Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ASIC1,NDRG2,APC,ARHGDIG,CACNA2D2,FOXN3,CHN2,RAB33A,ENTPD4,VCAN,TOM1,EDNRA,AASS,CORO2B,EFCAB2,PDLIM5,ZNF44,DISC1,LPAR4,GRIK5,KIFC3,MMP16,MYO7A,NF1,NOVA1,PALM,PDE4D,PFKFB2,RETREG1,PPP5C,SNRK,PTPRB,RASGRF1,GAL3ST4,KCTD17,RXRA,ZNF821,FRMPD1,ASAP3,DZIP1,KANSL3,ZNF667,PDZRN3,SPTAN1,ZBTB43,CABIN1,TNS1,VIPR2,GAN" Drug 3695_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "C1QTNF3,ALK,AMPD3,AMT,CDK10,PPP4R4,ARRB2,SCAPER,BAIAP3,TAOK2,RAB28,NRXN3,CNTN1,CREM,SH2B1,DTNA,IRAK4,CORO2B,SCARA3,GNG4,TJAP1,KCNJ5,KHK,MEIS1,TAGLN3,ZNF862,OCRL,FSD1,CEP41,PRPH,PTN,PTPRB,SCN8A,PKNOX2,SNCA,DOK5,KDM4C,SS18,ARC,ASTN2,MCF2L,KIAA1107,DNAH7,GPR161,CDK20,METTL3,ZBTB14,MPPE1,DPF3" Drug 4372_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "CDC42BPA,APAF1,ARSE,CHRD,ADGRB3,SCAPER,BAIAP3,SLC16A4,SEPT7,KCNAB3,SULT4A1,CNTN1,PCYT1B,VCAN,ARHGAP24,SPOCK2,ELMO1,KLHL3,EDNRA,FRY,ERBB2,F5,ZNF589,PDLIM5,RASL10A,RUNDC3A,ELOVL5,KIF5A,LAMA2,LIFR,MMP17,MYT1,PLCD1,PURG,CEP41,ZNF493,TRIM68,EMID1,KCNIP1,RBM34,IZUMO4,TCF4,HIF3A,HIRA,WIPF1,EMSY,KCNAB1,PLSCR4,HRASLS" Drug 4574_DN Bicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ADRA1D,MTUS1,NME5,KIF1A,CBFA2T2,ARHGAP33,RAB28,TPP1,PICK1,AKAP7,ARMC8,CSF1,SLITRK5,CHRDL1,ING4,MRNIP,BAIAP2,TRMO,PRELID3A,OGA,FYB1,FYN,SRCAP,USP19,SCIN,INPP5B,ITPKA,MX1,CNOT4,FA2H,PRKAR1B,MAPK7,CNNM2,CNTLN,PTCH1,ELOVL2,RPS6KA2,FNDC3A,PEX26,SLC9A5,ELMO2,ARHGAP26,ZBTB43,DOCK9,WNT7A,NDRG4,NT5M,EVI5,PHTF2" Drug 4005_UP Suprofen [40828-46-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.76E-08 2.96E-03 8.44E-06 9.50E-05 49 196 "ASPHD1,ADD2,SYT13,BIN1,CDC14B,CDK13,SYNJ2,BAIAP3,CFAP410,CA12,CSF1R,SEC14L5,SPOCK3,EDIL3,HIPK3,ETV1,OLFM1,FGFR1,AGAP2,OGA,GATM,SPACA9,CACFD1,IL12A,JAK2,KCNF1,KCNJ5,CNOT4,CLDN11,PCDH9,ENPP2,PFKFB4,NLE1,ELOVL2,BEND5,GAL3ST4,ZMAT4,RFX2,PNMA8A,GSTCD,DOK5,ZSWIM8,RBM26,COBL,OBSL1,CDK20,VGF,LAT2,KCNAB1" Drug ctd:C044887 beta-methylcholine CTD 6.83E-08 2.99E-03 8.50E-06 9.58E-05 257 1657 "ABCF1,ABR,ACADM,ASIC1,NDRG3,ADCY6,GALNT13,UNC5A,RNF150,INTS2,MTUS1,OSBPL1A,TBC1D14,SEMA6A,SPOP,GPRASP2,BEGAIN,AMH,LRCH2,PKP4,APAF1,UPRT,FAM131A,NUMB,RASL11B,DYNLL1,ATP1A1,ATP1B3,ATP6V0A1,KIF1A,BBS2,ARHGEF7,CASTOR3,MTMR3,CAMK2G,KRIT1,DCLK1,DIS3L,CHGB,SLIT2,IQCK,TBPL1,SMARCAL1,NSL1,PREPL,RNF14,HINFP,CSF2RA,ARHGEF10,CSNK1G3,RIMS4,CNTNAP2,PHF14,GPSM1,MYADM,CENPL,MATR3,INTS1,IP6K1,DBT,ARMCX2,TIAM2,PARD6A,SGSM2,DNAJB6,ABCC5,DNM1L,SEZ6L2,ANKRD46,CELSR3,PHF20L1,SUGP2,MBNL2,KMT5B,ASB3,EIF4G1,EIF4G2,COPS4,TNK2,EIF1,LRRC17,GPHN,RABEPK,NCALD,MRPL10,EXTL2,GMPR2,FKTN,STRADA,PRMT5,HPCAL4,IP6K2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,POMT1,USP21,NSG1,MPP6,OGA,FYN,FAM120B,ZNF234,ZNF274,MTHFD2,ZNF559,GPR162,GFRA2,RUNDC3A,MSL3,CBX1,PLPP7,BTN2A1,RNF165,GUCY1A1,MAN1B1,AGBL5,ICA1,LRRCC1,GATD1,KIF2A,MAP2,MAPT,LYPLAL1,MARK3,MEIS2,KCTD6,MYCN,MYT1,NBL1,NEK1,NFE2L2,CNOT4,SLC11A2,NRCAM,OPRL1,ETFRF1,PDCD2,PDPK1,SLC10A4,CYTL1,PFKFB3,PFKFB4,ZFYVE21,XRN1,PCDH18,PLXNB1,STRN3,ING3,FSD1,PPM1B,PPP2R2C,LRRN3,PPP3CC,CEP41,PKIA,MAPK3,SLC26A11,APTX,SPDL1,EML5,RIPOR1,TTC13,PPP2R3C,RAP1GDS1,RBBP6,RBBP8,RDX,RGS4,RGS12,CCDC25,RORB,ELP2,RPE,RTN1,RMI1,SBF1,TNFRSF19,SUPT20H,PUF60,FUZ,NBPF1,EPN2,DHX30,SLC6A8,BTBD7,ARFGAP1,MAST1,CDK5RAP2,SNAP25,SNCA,USP33,SOX11,SP2,NMNAT2,TEX2,LMO3,TROVE2,ZNF302,LARP4,PHLDB1,SULF2,NSFL1C,KLHL7,SUPT5H,SYNE2,PJA1,CAMTA1,EXOC7,ZFP90,TRIM2,TCF12,SLC35G2,SIRT1,ZNF106,SLC44A1,HEY1,ACTR6,TP53BP2,CDK20,SYNPO2,METTL3,TRIO,TRO,SSBP2,UBC,EIF4ENIF1,UBE2H,SLC35A4,UBTF,USP1,CCDC136,CCDC14,VSNL1,CLIP2,CLDND1,XPO1,ZNF32,NDRG4,ZNF142,POLR3H,FSTL5,ZNF189,SPIRE1,TFIP11,STOX2,PRDM8,TUBA1A,CIAPIN1,ITM2C,PCBP4,ST7,JMJD1C,FXR1,ST8SIA2,JPH3" Drug 6993_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.97E-08 3.05E-03 8.63E-06 9.72E-05 46 179 "ABHD6,ADRB2,NME5,MARK4,BMP7,ST3GAL5,BAIAP3,SPAG9,CLGN,AKAP12,CRY2,PDE4DIP,CTH,ARMCX2,OPTN,ENO2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,RNFT2,PADI2,MAP4,MAPT,MITF,PCDH9,SERPINI1,PLCD1,PRPH,SH3GL3,SYBU,WDR47,CCDC88A,SMARCD3,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SSBP2,SLC30A3,SLC17A7" Drug 5903_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.97E-08 3.05E-03 8.63E-06 9.72E-05 46 179 "NME5,SEMA6A,APAF1,BAIAP3,CLGN,WHRN,AKAP12,CRYM,PDE4DIP,SEC14L5,ARMCX2,FRY,FAM13A,DLC1,BAIAP2,FYN,CYP46A1,RAB40B,TDRKH,STON1,KCNB1,MAP2,MXI1,PCDH9,ENPP2,TMOD2,SERPINI1,RETREG1,PRPH,RADX,NUDT11,RPS6KA2,SH3GL3,WDR47,PKNOX2,SOX15,ARHGAP26,ELOVL4,RGL1,STXBP1,SYN1,ZEB1,HEY1,RUNDC3B,SLC30A3,SLC17A7" Drug CID000066161 MAPS Stitch 7.71E-08 3.38E-03 9.32E-06 1.05E-04 48 191 "METAP1D,TAOK1,MYH7B,APC,SPTBN4,MARK4,ATP6V0A1,KIF1A,CALM1,PRC1,DCLK1,BOC,DCTN1,DLX1,DNAH9,DPYSL2,TUBD1,TUBA1B,TUBB3,TUBA8,STMN2,CIT,SYNPO,KTN1,STMN1,MAP2,MAP4,MAP6,MAPT,MARK1,MBP,NEFM,NEFH,ENPP2,PLEC,FSD1,KANSL1,CLIP1,SPTAN1,SPTB,SYN2,SYP,ACTR6,NEIL2,TUBB2A,TUBB1,ANKS1B,TUBA1A" Drug 3975_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.71E-08 3.38E-03 9.32E-06 1.05E-04 48 191 "C1QTNF3,DOC2A,AMPD3,APC,ALDH7A1,GYG2,SLC16A4,CLTB,SLC4A8,CRMP1,CSF1,ARHGEF4,MAML1,EDN1,HIPK3,VPS13B,F5,FECH,FGFR1,FHL1,AGAP2,CGREF1,DLL3,SRCAP,TXNL4A,RAB30,GPR37,GRIK5,ITPKB,KCNJ5,KCNQ3,KIT,SMAD1,KITLG,NF1,CNOT4,P2RY1,PCDH9,CEP41,PRKCB,MAPK7,SEMA6D,UHRF1BP1L,TSPYL2,DICER1,HIRA,RPRM,SENP7" Drug 5572_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.87E-08 3.45E-03 9.32E-06 1.05E-04 45 174 "NME5,KIAA1324,ST3GAL5,GYG2,USP2,CLGN,AKAP12,PDE4DIP,ARMCX2,OPTN,FAM13A,STX2,HPCAL4,IQCG,FYN,CYP46A1,RAB40B,STON1,MXI1,NEK1,TMOD2,SERPINI1,PKIA,GRAMD1C,PRPH,SH3GL3,PPM1E,ASAP3,WDR47,CCDC88A,SLC9A5,PEG10,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,SLC30A3,SLC17A7,ITM2C" Drug 3930_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "KCNAB2,DNAH17,MARK4,SLC4A4,SLC2A11,ADAM15,CFLAR,CA4,CACNA1A,HAP1,ARHGEF1,AKAP7,RCHY1,CRMP1,CSF1,CDON,SLC12A6,HSD17B14,VPS13B,FECH,FGFR1,SRCAP,RUNDC3A,GPER1,GRIK5,IL6ST,INPP5B,ITPKB,KCNN1,KCNQ3,KHK,MAN2A2,GIT1,ADAM22,NPY,PDE1C,PFKFB2,NKAIN1,SH3GL3,FNDC3A,PEG10,SS18,EXOC7,CDK20,VIPR2,WIPF1,EMSY,SLC17A7,PHTF2" Drug 5089_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "CDC42BPA,GAS7,APOC1,ATP2B2,CACNA1G,LDLRAD4,CA4,CACNA2D1,CAMK2B,USP2,SLC16A4,CD86,KCNAB3,CRLF1,TAOK2,CLTB,COL9A3,AATK,CSF1,RASGRP2,CDKL3,FGF1,SIGLEC8,LPAR4,ITGA7,PACRG,AFDN,NELL2,PFKFB2,LRRN3,MAPK7,GRAMD1C,ZCWPW1,PBRM1,FBXW7,SCN2B,SH3BP2,ST8SIA1,HECW1,ASTN2,TACR1,MCF2L,RPGRIP1L,DOCK9,WIPF1,SPHK2,TFIP11,SLC30A3,FAM13C" Drug 4127_UP Sulmazole [73384-60-8]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ASPHD1,TRMT9B,APAF1,APBB2,GAS7,BAIAP3,CLGN,TAOK2,VAX2,ARMC8,WHRN,ABCG1,CSF1,GREB1,DAPK1,DAPK3,EGR3,TRAF3IP2,NEU3,GSTM5,ICA1,KCNN1,MSI1,NF1,NTRK3,GPR85,RETREG1,PLCD1,MAPK10,PTPRB,ZSCAN2,RFX3,RGS12,NUDT11,RPS6KA2,SH3BP2,FBXO11,CXXC4,COA1,SMARCD3,SNCA,RBM34,ATP10B,EXOC7,ADGRL3,KIAA1107,SYNE1,SLC19A3,PARP11" Drug 4570_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ASPHD1,C1QTNF3,LTBP4,CDC14B,ATP6V0A1,BMP7,IL33,CAMK2B,RUNX1T1,USP2,ARHGEF2,ASIC3,ABCG2,PDE4DIP,CNTNAP2,PHF14,RIMS2,DMPK,EDN3,HIPK3,CDKL3,ST3GAL6,OLFM1,SEMA4D,ZNF44,GAD1,B4GALNT1,ADAM22,MSR1,PDE4D,GPR85,RETREG1,PPP2R2B,PTPRN2,ACSS3,KHDRBS2,RASA3,FBXO11,SNAP25,TSNAXIP1,KDM4C,ARHGAP26,PCDHGB6,SLC19A3,GPR161,TK2,ZNF74,REEP1,DPF3" Drug 3076_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "AMH,CDC42BPA,APBB2,BCAS1,BMP7,GYG2,CACNA1I,HAP1,RUNX1T1,CBFA2T2,CHN2,CHRNA4,SLIT2,RAB33A,CNTN1,IQCK,ABI3BP,NCOR2,CSF1,CNTNAP2,MFAP3L,EDIL3,CELSR3,FER,PRELID3A,ALDH1L1,ADAM28,POLL,GNAO1,MAP4,MMP16,MYO6,NPR2,PCBP3,MTRF1L,CEP41,TCP11L1,ST6GAL1,SLC14A1,FAIM2,HECW1,SPTAN1,SEPT8,SYT5,WSCD1,ICAM5,CHST5,ZKSCAN5,RPRM" Drug 3343_DN Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ADORA2A,AP2A2,AMPD3,BIN1,APOC1,CFLAR,SYNJ2,SCAPER,MAGI1,B4GALT6,BAG4,NCOR1,CSF1,DCAF8,DAPK3,RGS17,STX2,CSPG5,GALC,ZNF276,TXNL4A,RAB30,POLL,INPP5B,KCNJ5,MAP4,MATK,ADAM22,NF1,NFYA,RETREG1,PLCD1,PRKAR1B,ZSCAN32,CEP97,AMBRA1,SYBU,ABLIM3,BTBD7,ZKSCAN3,KDM4C,THSD1,ELOVL4,PHLDB1,PLCB1,SMG6,PLPPR2,VGF,SEMA3B" Drug 4394_UP Levodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ASIC1,ARHGDIG,CDK13,BAIAP3,CACNA1A,HIP1R,P2RX6,CD86,TAOK2,LY86,RIMS2,DTNB,AASS,EIF4G2,ELN,IGSF6,SPEG,ST3GAL6,OLFM1,HPCAL4,ADAM28,GRIK5,GRM2,ITGA7,MAPT,MGAT3,ADAM22,MYCN,NTRK2,P2RY1,GPR85,CCDC40,RPS6KA2,SEMA6D,ZFP2,SH3BP2,KANSL3,DOK5,IZUMO4,ARHGAP26,ATP10B,TROVE2,TBCEL,WSCD1,DOCK9,TNS1,WIPF1,LAT2,ADAMTS9" Drug 4347_DN Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ALK,AMPD3,BIN1,APBA2,CFLAR,SYNJ2,CA12,MAGI1,STOML1,TBC1D5,GIT2,MFAP3L,SLC12A6,DTNA,EIF4G2,MRNIP,RRAGB,FAM198B,AGAP2,GCNT2,SRCAP,RUNDC3A,GRIK5,KIF2A,MAPT,ZNF862,SLC11A2,RETREG2,RGS12,ZFHX4,RASA3,PEX26,EPN2,CXXC4,COA1,SMARCD3,KDM4C,ZBTB43,CLSTN2,PLCB1,ANKRD12,KIAA1107,TBL1X,WSCD1,ZEB1,ZNF24,ITM2C,KAT6A,GAN" Drug 3897_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ALK,TRMT9B,AMPH,CDC42BPA,APAF1,RUNX1T1,CNTN1,WHRN,OSBPL3,ARHGAP24,SPOCK2,DBT,PLXNC1,LRRC17,FGFR3,FOXF2,SEMA4D,ANKFY1,PDLIM5,GAD1,DISC1,HLF,TJAP1,KCNJ5,L1CAM,MATN3,ADAM22,MX1,P2RY13,CLDN11,PDE1C,CEP41,PRKCB,ELOVL2,RPS6KA2,KCNIP1,ZFP2,SH3GL3,LIMS2,RBM34,SPP1,PEG10,LMO3,TBCEL,PCDHGA10,PCDHA5,DICER1,UBE3A,WIPF1" Drug 6091_UP Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NDRG2,C1QTNF1,ADGRF5,SEMA7A,APOC1,SPTBN4,N4BP2L1,SCAPER,BAIAP3,LDLRAD4,CALB2,CAMK2B,CBARP,CNTNAP2,DBT,EBI3,HSD17B14,ZNF589,FHL1,CSDC2,RUNDC3A,PRUNE2,GPER1,GRIK5,ATXN2L,ITGA7,KCNH2,LAMA2,LSS,MAP4,KITLG,MN1,ZNF862,PCDH9,PLXNB1,SALL1,ASAP3,SLC2A5,ARHGEF40,KDM4B,SPTAN1,RGL1,DMXL2,DOCK9,TNS2,TNS1,OSBP2,LAT2,AP3B2" Drug 6412_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ADRA1D,NME5,ADGRF5,BEGAIN,TRMT9B,APBB2,PLA2G4C,MARK4,ATP2B2,PROM1,CAMK2B,LDB2,TPP1,WHRN,RGS6,EXOG,SNX29,C3orf18,RASGRP2,DLC1,OLFM1,AGAP2,PDLIM5,TMEM8B,LPAR4,GPER1,PCLO,ATXN2L,ICA1,C2orf72,MAN2A2,MYT1,PCBP3,NTRK2,PALM,SLC25A23,NECAB2,PPP5C,MAPK10,RGS12,RASA3,SLC6A8,SLC6A11,CDK19,SPART,ARC,KIAA0930,TUBB1,KCNAB1" Drug 3702_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "C1QTNF3,APC,CDK10,FAM189A2,CNTFR,IQCK,BAG4,CRY2,NCOR2,CSNK1E,CDON,EDNRA,NCALD,CDKL3,SCML2,FGF1,TRMO,OGA,FYN,TRAF3IP2,BTN2A1,SHISAL1,INPP5B,KHK,KIFC3,MAPT,GIT1,NF1,OPRL1,PRKAR1B,CNTLN,PTPRH,RAD51D,ZNF821,ST6GAL1,ELMO2,SNCA,SP4,TROVE2,THSD1,SS18,IQCE,TCF4,DNAH7,CDK20,VGF,LMF1,KLC2,SEMA3B" Drug 2237_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NME5,AMPH,GAS7,RGS20,MARK4,BAIAP3,LDLRAD4,CA4,CAMK2B,RHBDL1,KCNAB3,TAOK2,VCAN,DCAF4,EDN1,SRPK3,RCAN2,FYB1,ZNF44,GABRG2,MSL3,ITPKA,MAN2A2,MATN3,NELL2,SLC11A2,PALM,PFKFB2,PLCD1,C19orf57,PRKCB,MAPK7,TMEM104,KLHDC8A,RPS6KA2,SEMA6D,SCN8A,SH3BP2,SH3GL3,SLC9A5,KDM4B,PEG10,DOCK9,CRTC1,TNS1,LAT2,XRCC4,NT5M,KAT6A" Drug 2254_DN Etodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NDRG2,BEGAIN,APOC1,ARRB2,DNAH17,RASL11B,CCNT1,ARHGEF2,CACNA2D2,PLEKHB1,SLIT2,LHX2,CLTB,BAG4,SIPA1L1,GREB1,RIMS2,PPP6R2,OPTN,PLXNC1,MRNIP,SEMA4D,TPK1,SEPT9,GCNT2,GLYR1,GNG4,STON1,CNTRL,GRIK5,CACFD1,GSN,ELOVL5,MBD1,MSI1,NLE1,STRN3,GRAMD1C,PRODH,ELOVL2,SNCA,TSNAXIP1,KIAA0930,TNS2,CABIN1,SLC30A3,EMSY,SEMA3B,TIGD6" Drug 3040_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "PDE8B,ADGRB1,RGS11,KSR1,BAIAP3,CA4,THSD7A,KALRN,CAMK2A,LARGE1,CHGB,CSF1,RGS6,ARHGEF10,DZIP3,MFAP3L,AASS,APC2,NSG1,DOT1L,SIGLEC8,MSTN,RUNDC3A,GNAL,PRUNE2,GUCY1A1,KIT,LAMA2,SMAD9,MPP2,NRCAM,OPRL1,PPP1R1A,RELN,CNNM2,BCAS3,PTPN13,PTPRB,RGS12,NUDT11,NLGN1,SLC11A1,TACR1,DNAH7,BHLHB9,TRPS1,LMF1,ZNF711,DNALI1" Drug 4502_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "APOC1,BCAS1,ATP2B2,CFAP410,RUNX1T1,NRXN3,STOML1,COL9A3,NCOR2,ARHGEF10,PDE4DIP,SEC14L5,MFAP3L,EDNRB,CELSR3,MBNL2,LRRC17,CORO2B,KAT8,FGF1,OLFM1,FGF14,ALDH1L1,GPD1,ICA1,IFI16,KCNN1,LAMA2,MAP4,GIT1,MT1M,NPY,NPR2,PCBP3,NTRK2,RETREG1,CEP41,PTCH1,ELOVL2,PTPRH,KCTD17,KCNIP1,DZIP1,RBM34,SOX15,KLHL4,CHST5,WIPF1,LAT2" Drug 4702_DN Flurandrenolide [1524-88-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NDRG3,ADCY6,SEMA6A,PPFIA3,CDK13,MARK4,KIF1A,CFLAR,CAMK2G,ARHGAP33,CREM,LRIG1,GREB1,DCAF8,DAPK3,DBN1,JAKMIP2,RUSC2,PARD6A,RCAN1,SUGP2,MBNL2,HSD17B14,COQ7,ZNF589,PDLIM5,TPK1,ERAP1,DISC1,MSL3,POLL,GPD2,DHX35,LMO2,MITF,LYRM9,NF1,NFYA,NPTX1,RETREG1,FBXW7,SBF1,FNDC3A,BTBD7,KIF13A,THSD1,RPGRIP1L,VIPR2,GAN" Drug 3209_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "ADD2,APC,CDK13,PDE8B,ATP2B2,MYRF,CFAP410,KALRN,DGKI,FOXN3,PLAA,WHRN,BAG4,CNTNAP2,DCAF8,ARMCX2,HEPH,DTNB,TNK2,FHL1,SYNPO,AFDN,NOVA2,NTRK2,POU6F1,LRRN3,RIPOR1,RGS12,KCTD17,TCP11L1,SLC6A8,ARHGEF40,SMARCC2,SNCA,KIF13A,DOK5,ZSWIM8,ARHGAP26,RBM26,LHPP,ATP10B,SYN2,TACR1,EXOC7,DOCK9,OBSL1,LAT2,KCNK12,PHTF2" Drug 6062_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NME5,LTBP4,BEGAIN,AMPD3,AMT,GAS7,PLA2G4C,CACNA2D1,ARHGEF6,SNPH,DUSP9,SPEG,F5,REEP2,FGF13,FGFR1,LYVE1,STON1,CACFD1,GRIN2C,TJAP1,MX1,NPY,NOVA2,PALM,TMOD2,PFKFB2,PLCD1,MTRF1L,LRRN3,ZNF493,RGS12,TCP11L1,KCNIP1,SNAP25,HECW1,UNC5B,ARHGAP26,SPART,LMO3,ST5,ARC,KIAA1107,CRTC1,HIF3A,DNAH7,RUNDC3B,PDIA2,VSNL1" Drug 4415_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.01E-08 3.51E-03 9.32E-06 1.05E-04 49 197 "NME5,AMH,AMPD3,BIN1,APBB2,RGS20,PDE8B,MARK4,ALDH7A1,CFLAR,LDLRAD4,CBFA2T2,RCBTB2,PICK1,SH2B1,CRY2,CSF1R,RIMS2,SPOCK2,ZNF804A,RUSC2,HSD17B14,STX2,ZNF589,FGF12,SRCAP,POLL,RASSF8,ATXN2L,KHK,KPNA5,MAP4,MIA2,MSI1,ZNF862,NFYA,NPR2,MAPK7,NKAIN1,C1orf54,RBM34,SPTAN1,ARC,CRTC1,FLRT2,VLDLR,SPHK2,HPS4,SLC17A7" Drug 7407_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.34E-08 3.66E-03 9.62E-06 1.08E-04 46 180 "NME5,APLP1,ARNTL,MARK4,ST3GAL5,SCAPER,NECTIN3,AKAP12,DZIP3,ARMCX2,TSPAN5,PHF20L1,MRNIP,RASGRP2,NBEA,FYN,RAB40B,STON1,RNFT2,KCNH2,MAP2,MPP2,MXI1,PCDH9,SERPINI1,MBOAT7,PRPH,CNNM2,PTCH1,SH3BGR,SH3GL3,FAM214B,SMARCD3,ELOVL4,CEP68,TTBK2,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,MAP3K12,SLC17A7,IFT88" Drug 6579_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.34E-08 3.66E-03 9.62E-06 1.08E-04 46 180 "ABHD6,APLP1,MARK4,KIF1A,BMP7,ST3GAL5,BAIAP3,WHRN,AKAP12,PDE4DIP,CTH,DOCK4,ARMCX2,JAKMIP2,OPTN,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,RNFT2,MXI1,NEK1,PCDH9,SERPINI1,PKIA,GRAMD1C,PRPH,SH3BGR,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,SPTAN1,THSD1,ELOVL4,RGL1,STX1A,STXBP1,HEY1,RUNDC3B,REEP1,GDPD5,SLC17A7" Drug 4072_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.34E-08 3.66E-03 9.62E-06 1.08E-04 46 180 "ADRB2,MTUS1,SHROOM2,ARNTL,ST3GAL5,HIP1R,USP2,SYNGR3,CHN2,ABCG1,SUSD5,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,FGFR3,BAIAP2,CYP46A1,PCDH17,STON1,GUCY1B1,FAM69A,MMP16,TAGLN3,NTRK2,PCDH9,ENPP2,SERPINI1,PTCH1,ENOX1,RFX2,RGS4,RPS6KA2,SH3GL3,ASAP3,ARHGAP26,ELOVL4,CEP68,RGL1,SYT1,COBL,SSBP2,SLC30A3,PLSCR4,DPF3" Drug 1209_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.16E-08 4.01E-03 1.05E-05 1.18E-04 48 192 "APBB2,ARNTL,MARK4,ST3GAL5,SCAPER,FOXN3,CHN2,RAB28,AKAP5,PDE4DIP,SLITRK5,C2CD2L,PLPPR4,TMCC2,FYN,STON1,GUCY1B1,FAM69A,ITGA7,MAPT,PFKFB4,PIK3R1,RETREG1,PTCH1,ENOX1,GAL3ST4,RGS4,NUDT11,FBXW7,RXRA,SATB1,RASA3,SH3GL3,SYBU,BTBD7,TSNAXIP1,SPTB,ELOVL4,PHLDB1,VPS13A,SYT1,COBL,SMG6,TRIM2,HEY1,UGT8,FZD3,PHTF2" Drug 3929_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.16E-08 4.01E-03 1.05E-05 1.18E-04 48 192 "NME5,ALCAM,LTBP4,APBA2,CDC14B,MARK4,SCAPER,CACNA1A,ARHGEF2,FOXN3,CNTFR,AKAP7,SH2B1,RIMS2,PPP6R2,TMCC2,CDON,DTNA,HIPK3,FCF1,FGFR3,DLL3,SRCAP,TDRKH,ADAMTS13,KCNJ5,KCNN1,IPO5,NF1,CNOT4,NTRK2,SERPINI1,TCP11L1,SEMA6D,FAM214B,COA1,SNCA,KDM4B,PEG10,SYN2,DMXL2,AP4E1,CABIN1,HIRA,SPHK2,SLC17A7,MPPE1,PHTF2" Drug ctd:D004397 Fonofos CTD 9.26E-08 4.06E-03 1.05E-05 1.18E-04 128 714 "ADCY8,FZD9,ADRB2,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,LGR5,CDK10,ZNF583,KIF1A,ADAM23,NRP2,CD38,LARGE1,ZNF445,UBE2L6,NGEF,LY86,MYRIP,NRG2,CRMP1,CNTNAP2,ERC2,ARMCX2,SV2B,HS3ST2,RGS17,ZNF549,NRN1,ZNF585B,FGF12,AFF2,HHIPL1,FYB1,MEGF10,GAD1,ZNF559,SYT17,NTNG2,LNX1,MCHR1,GRIN2C,GRM2,PTPRT,GSTM5,SOX21,PADI2,FRMD5,HLF,ZNF491,USP51,IRF8,LAMA2,LIG4,MATK,MATN3,MBP,MN1,MYCN,FXYD7,NEFM,NPTX2,NTRK3,CYTL1,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RASGRF1,BEND5,KHDRBS2,RET,FIGN,ZDHHC4,ZNF671,HUNK,CCDC112,SALL1,SCP2,HES6,SEC14L1,GALNT10,FERMT1,ST6GAL1,DZIP1,ELMO2,INAVA,SNRPN,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,SYP,ASTN2,PCDHGB7,NAT16,TMEM121,TIMP4,PRRT1,IL34,RUNDC3B,FLRT2,VLDLR,KCNK12,ZIC1,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PLD4,DNAH10,NETO1" Drug 3243_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.44E-08 4.14E-03 1.05E-05 1.18E-04 45 175 "NME5,SEMA6A,BMP7,ST3GAL5,CLGN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,TSPAN5,OPTN,MBNL2,RASGRP2,STX2,HPCAL4,FYN,CYP46A1,RAB40B,STON1,FAM69A,MITF,NEK1,PCDH9,SERPINI1,PLCD1,PMP22,PKIA,PRPH,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,ELOVL4,RGL1,STXBP1,ZEB1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,REEP1,SLC17A7,ITM2C" Drug 4498_UP Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "AGT,BEGAIN,CFLAR,BMPR1B,EPS15L1,CNTFR,AKAP5,ABCG1,CSF1,RGS6,CNTNAP2,CYBB,GSDME,ECM2,COQ7,DENND4A,NCALD,ZNF549,PIPOX,ARMCX1,FGFR1,IRF8,KCNH2,SMAD1,MMP16,ADAM22,NTRK2,ENPP2,PFKFB2,CEP41,ELOVL2,PTPRN2,ZSCAN2,RGS4,STUM,DZIP1,FAM214B,CXXC4,FAIM2,ZHX3,IZUMO4,SPTAN1,THSD1,COBL,KLHL4,TRIM2,VIPR2,SPHK2,KCNAB1" Drug 5495_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "AGT,KIAA1324,TRMT9B,ATP2A2,N4BP2L1,LDLRAD4,CAMK2B,CD86,CACNA2D2,ABI3BP,CSF1R,PDE4DIP,CNTNAP2,BRINP1,GIT2,MED12,MBNL2,FGFR1,BAIAP2,CAMKK2,DISC1,CNTRL,CACFD1,GUCY1B1,PADI2,DHX35,IL6ST,KCNB1,KHK,LIG4,SMAD1,MAN2A2,SETD4,STRN3,PPARA,ZNF821,BTBD7,ZKSCAN3,COA1,PEG10,CLSTN2,THSD1,TBL1X,KIAA0930,RPGRIP1L,TRPM2,EVI5,SLC17A7,KCNAB1" Drug 6750_UP Hesperetin [520-33-2]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "DDO,ADGRB2,CFAP410,CAMK2B,KCNAB3,CACNA2D2,CHN2,CABP1,ABCG1,PDE4DIP,FAM131B,INTS1,DAPK3,DRP2,EDN3,EDNRB,NCALD,F5,ZMYND10,FGFR1,ALDH1L1,SRCAP,TOX3,GNAL,PTPRT,HNF4G,ADAM11,ADAM22,NEFM,NNAT,PDE4D,GPR85,PRKCB,PTH1R,ENOX1,SLA,PREX2,SLC11A1,ZC3H13,DDN,PCDHGB6,FAM189A1,TPM2,RPRM,VLDLR,EMSY,NT5M,SEMA3B,KCNAB1" Drug 7497_UP CP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ASPHD1,KIAA1324,AK2,LTBP4,CDC42BPA,GAS7,APLP1,PPFIA3,CFLAR,FUBP1,MTMR2,GYG2,CAMK2B,CREM,PDE4DIP,RIMS2,DMPK,FEM1B,CELSR3,EIF5,REEP2,BAIAP2,COPS8,SLC2A6,NXPH3,MGAT3,NEK1,CDK18,NECAB2,CNNM2,PTCH1,RGS12,KCTD17,EMID1,ZNF821,SYBU,BTBD7,SLC22A4,UNC5B,IQSEC2,CDK19,TACC1,EXOC7,CRTC1,PARD3,TRIO,PLPPR2,ZBTB14,MAP3K12" Drug 4251_UP Antipyrine [60-80-0]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ADORA2A,NME5,PKP4,ATP2B2,N4BP2L1,ATP6V0A1,BMP7,SYNJ2,HAP1,HIP1R,RUNX1T1,KCNAB3,FOXN3,SEC31B,RGS6,PDE4DIP,DMPK,IRAK4,TENM1,PTK2B,DCTN2,ELOVL5,IL6ST,KIF5A,KIT,SMAD1,MAP2,ADAM22,MSR1,TAGLN3,NPTX1,PCBP3,NRCAM,BEND5,RGS4,SEMA6D,FBXO11,ST6GAL1,OGDHL,SNCA,PDZRN3,HECW1,ZC3H13,SPTB,MCF2L,ADGRL3,TPM1,TUBB1,UBE3A" Drug 5047_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ASIC1,APAF1,APC,MARK4,BMP7,GYG2,CFAP410,CHN2,FAM131B,DAPK1,DUSP9,SEMA3D,COQ7,SPEG,ETV1,ST3GAL6,FGF1,PDLIM5,PRELID3A,GPER1,GRIK5,ATXN2L,IRF8,IL6R,LMO2,MATN3,KITLG,CNOT4,NPTX1,NPTX2,PCBP3,NTRK2,RETREG1,PLCD1,PRKAR1B,PTPRN2,MARCH1,PID1,RPS20,SH3BP2,KIF13A,KDM4B,ZHX3,PHLDB1,TBCEL,CRTC1,CHST5,CA14,SEMA3B" Drug 6105_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "AMPD3,GAS7,ARHGDIG,PDE8B,DNAH17,NCOA1,MTMR3,SGCE,CA4,CACNA2D2,AKAP7,RCHY1,CSF1R,PDE4DIP,GREB1,EGFR,MBNL2,ING4,FAM198B,BAIAP2,GLYR1,GPER1,JAK2,IPO5,ADAM22,NF1,GPR85,GRAMD1C,ZSCAN2,SEMA6D,RASA3,FRMPD1,LIMS2,SMARCD3,MAPKBP1,SNCA,KIF13A,ZHX3,IQSEC2,PLCB1,TBCEL,IQCE,DOCK9,TK2,ZKSCAN5,FAM155A,WIPF1,ZNF45,SENP7" Drug 6499_UP Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "SEMA6A,ALK,APBA2,ARHGDIG,ATP2B2,BACH1,SLC16A4,DGKI,TAOK2,STOML1,HOMER3,CPS1,RASSF2,ELMO1,SPOCK3,RCAN1,DTNA,EGR3,ANKFY1,DCTN2,FAM49B,TXNL4A,GPR75,MSL3,GNAL,GPER1,GRB10,IGF1,KCNJ5,KCNN1,MATK,MBD1,MMP16,MSI1,MYT1,PPP5C,RGS3,GSTCD,PREX2,ARHGAP26,STX1A,TRIM2,PCDHGA10,SLC44A1,TLR4,CABIN1,HIRA,WIPF1,PLSCR4" Drug 6991_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ADRA1D,SRPX,ARHGDIG,SLC2A11,CAMK2G,ARHGAP33,B4GALT6,COL4A5,ENTPD4,C2CD2L,SGSM2,MED12,DUSP9,ENO2,ANKMY1,ZNF589,FHL1,ALDH1L1,GLYR1,ATXN2L,MAP4,MAPT,MIA2,MID1,ADAM22,NF1,RETREG1,PLTP,PLXNB1,SNRK,KHDRBS2,GTDC1,ZFHX4,SAFB,SH3BP2,SLC22A4,ZKSCAN3,COA1,MAPKBP1,ZNF415,CDK19,ELOVL4,STX1A,WSCD1,THRA,TPM1,TRPM2,SEMA3B,PHTF2" Drug 4101_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "AGT,APOC1,PRX,ARHGDIG,SLC4A4,RGS11,SCAPER,BAIAP3,CA4,CACNA2D1,RUNX1T1,CCK,SLC16A4,AKAP6,CABP1,CSF1,RGS6,LRIG1,SUSD5,RIPOR2,C2CD2L,DRP2,EPB41,ERBB4,F5,SIGLEC8,GFER,GPR75,POLL,PRUNE2,SOX21,ADAM11,MSR1,MT1M,MYO7A,NPY,NTRK3,PTH1R,PTPRN2,PBRM1,ST8SIA1,ARHGAP26,ATP10B,SST,SYT5,CRTC1,AMACR,LAT2,KCNAB1" Drug 3728_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ADD2,LTBP4,APC,BCAS1,PPP4R4,SYNJ1,HAP1,RUNX1T1,USP2,SYNGR3,CDO1,TAOK2,TPP1,STOML1,ABCG2,AKAP5,BRINP1,EXOG,SHANK1,ECM2,FCF1,SEMA3D,EGFR,REEP2,GNAL,PRUNE2,STON1,NXPH3,IRF8,MATK,NF1,NOVA2,NTRK2,CLDN11,NLE1,RGS4,FNDC3A,ZNF334,RBM34,KDM4B,KDM4C,NFASC,LHPP,ATP10B,ARC,SLC44A1,CDK20,TRIO,TRO" Drug 3235_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.49E-08 4.16E-03 1.05E-05 1.18E-04 49 198 "ADORA1,ADRA1D,CDK10,BCL7A,CFLAR,BAIAP3,EPS15L1,WHRN,CREM,PDE4DIP,INTS1,MAML1,MFAP3L,SUGP2,IRAK4,RASGRP2,ERBB2,ANKMY1,DISC1,SRCAP,MALT1,ATXN2L,INPP1,LMO2,MAP4,MITF,MSI1,ADAM22,PALM,PCDH9,PRKAR1B,C1orf54,RGS12,RPS6KA2,FAM214B,ZHX3,IQSEC2,SPART,CLSTN2,KIAA0930,PCDHA5,ZNF34,PIK3R5,RUNDC3B,ZKSCAN5,VIPR2,ZBTB38,SEMA3B,EPM2A" Drug 1535_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.97E-08 4.37E-03 1.10E-05 1.24E-04 46 181 "NME5,KIAA1324,PPP4R4,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,ARMCX2,JAKMIP2,TSPAN5,OPTN,MBNL2,RASGRP2,STX2,BAIAP2,FYN,INPP5K,CYP46A1,RAB40B,STON1,MXI1,PCDH9,PDE4A,SERPINI1,PKIA,PRPH,RPS6KA2,SGK1,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,FAM214B,ELOVL4,RGL1,STXBP1,ZEB1,TRIM2,HEY1,BEX4,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug 7453_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.97E-08 4.37E-03 1.10E-05 1.24E-04 46 181 "NME5,MARK4,BMP7,ST3GAL5,RAB29,CLGN,WHRN,AKAP12,ARMCX2,MRNIP,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,INPP5B,MAP4,MPP2,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PLCD1,PKIA,GRAMD1C,PRPH,RPS6KA2,SH3BGR,SH3GL3,WDR47,FAM214B,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,TACC1,KIAA0930,TRIM2,HEY1,RUNDC3B,SSBP2,SLC30A3,SLC17A7" Drug 2567_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 4.76E-03 1.15E-05 1.29E-04 48 193 "NDRG2,PPFIA4,APC,FAM131A,MTMR3,FOXN3,TPP1,CPS1,SGSM2,CDON,SEZ6L2,CELSR3,FAM13A,ELN,ENO2,PIPOX,DLC1,ST3GAL6,FGFR1,PDLIM5,OGA,SEPT9,NCKAP1L,ATXN2L,ITGA7,MEF2C,AFDN,CNOT4,CCSER2,PTCH1,CEP97,SH3BP2,CNKSR2,SLC2A5,EPN2,SLC6A8,BTBD7,IZUMO4,SPTAN1,PDLIM2,CRTC1,TNS1,TPM1,FLRT2,TRIM9,MAP3K12,PCBP4,FAM13C" Drug 5088_DN Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 4.76E-03 1.15E-05 1.29E-04 48 193 "APOC1,ARNTL,MARCH3,SLC4A4,ADAM15,CCNT1,HOMER3,CREM,VCAN,FAM169A,SLITRK5,EDIL3,FCF1,OPTN,MBNL2,IRAK4,TUBD1,ETV1,VPS26C,RRAGB,ANKFY1,TRMO,PDLIM5,GAD1,ERAP1,ARFIP1,SPIN1,IL6ST,INPP5B,JAK2,KCNN1,NFYA,CNOT4,STRN3,SAMD9,PTN,RAD51D,ZNF671,CSRNP3,CCDC88A,SLC14A1,SNCA,SS18,NXT2,TCF4,CABIN1,ZNF24,SMIM8" Drug 3866_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 4.76E-03 1.15E-05 1.29E-04 48 193 "ADORA2A,DOC2A,APOC1,ARRB1,CFLAR,SYNJ1,SYNJ2,CA4,TAOK2,SLIT2,HOMER3,AKAP7,RIMS2,ARHGAP32,DAPK3,NR1D2,DTNA,EIF4G1,FAM198B,PDLIM5,GFER,GLYR1,HTATSF1,STON1,CLASRP,LSS,KITLG,ADAM22,NEK1,NF1,PFKFB2,PIK3R1,SLC25A23,MBOAT7,SNRK,ZSCAN2,ENOX1,CARF,TCP11L1,EMID1,PEX26,BTBD7,ARHGAP26,TBL1X,TRIO,REEP1,PHTF2,RNF146" Drug ctd:D012834 Silver CTD 1.11E-07 4.87E-03 1.15E-05 1.29E-04 295 1958 "FMNL2,RNF157,USP31,ADORA2A,UNC5A,SLC24A4,AP2A1,AGT,SEMA6A,ALCAM,CARNS1,PCDH10,DOC2A,AMPD3,ANK2,LCORL,PARG,EPB41L5,PHYHD1,BCAS1,SEMA4G,MADD,TMEFF1,ARNTL,PLA2G4C,RASL11B,DYNLL1,RIPK1,BID,CFLAR,PROM1,KSR1,C5,RAB29,CACNA1A,CACNA1B,CACNA2D1,THSD7A,PTBP2,CBR1,SCARB1,SYNGR3,LONRF2,ZNF445,UBE2L6,FOXN3,SOCS6,SLIT2,FAM189A2,CNR1,WHRN,COL4A5,MYRIP,ZNF521,IGDCC3,NECTIN3,AKAP12,CRY2,GDA,VCAN,SOCS5,SLITRK5,UBXN2A,HDAC9,RIPOR2,CENPL,MATR3,DGKG,ZNF804A,HEPH,LYPD1,SNAP91,PARD6A,SV2B,CHRDL1,EXOG,HS3ST2,CDON,CPEB2,SLC25A18,RCAN1,ARRDC4,E2F5,EEF1D,MBNL2,RASA4,AASS,ELN,EMX2,HSD17B14,TUBD1,RCAN2,LRRC17,MTSS1L,RABEPK,RAB9B,ERCC2,EYA1,MRVI1,REEP2,FCGR1A,FKTN,SLC9B2,PRKAG2,POLK,MEX3B,AGAP2,EVL,ATP13A4,FLT1,SYT3,AKAP3,ZBED3,UFM1,TRIM16,PRELID3A,DOT1L,FYN,MEGF10,GABRG2,IQGAP2,SYT17,MSTN,CYP46A1,RUNDC3A,SPIN1,GLI2,LOXL3,LPAR4,CNTRL,GRIA2,SERP2,CIT,RNFT2,HAS2,TOX2,MAN1B1,USP51,IFI16,IGF1,LRRCC1,INPP1,INSM1,SLC35G1,KCNN2,LAMP2,LIMS1,LMO2,NCOA7,LSS,MAP2,MAPT,MAT2A,LRP1B,SHC3,MEF2C,MEST,KITLG,SCAMP5,PPM1L,MMP16,MN1,MOV10,MT1M,MX1,MYCN,LAYN,P2RY13,NBL1,NCF2,NDP,NFE2L2,NFIX,NME4,NPR2,P2RX7,PAX6,PDE1C,PDE4A,PDE4B,PDPK1,GPR173,GPR85,SERPINI1,SEMA5B,PIK3C2A,PIK3R1,XRN1,TMEM38A,SMOX,PLTP,PNMA3,SH3KBP1,PPP1R1A,NKAIN4,MAPK3,MAPK9,GDPD2,TMEM104,QRICH1,PTK2,PTN,PTPRE,PID1,IQSEC3,FAT4,ZCWPW1,RASGRF1,RDX,ZMAT4,RNASE1,ZFHX4,MCMBP,FAM161B,RXRA,SEMA6D,ATXN7,PEAR1,ASAP3,FHOD3,ST6GAL1,CCDC92,PREX2,PPP4R3A,PKNOX2,RADIL,SLC11A1,ELMO2,BTBD7,ATF7IP,SLC22A4,SNAP25,SNCA,PDZRN3,SOX3,SPP1,ATP10B,ITPRID2,SST,NXT2,ELOVL4,RGL1,KANK1,STXBP1,SYN1,SYN2,SYP,TACC1,DNMBP,ADGRL3,ZEB1,TCF12,SYNE1,TNS2,ARHGAP9,CCDC173,VWCE,ZFPM2,AKTIP,CDH22,SLC44A1,TPM1,IL34,TRIO,AMACR,TRPS1,SSBP2,CLHC1,UCHL1,FLRT2,WIPF1,KLC2,LGI4,ZIC1,ZIC2,MKRN3,LYPD6,POLR3H,DPYSL5,PRDM8,RNF103,ADAMTS9,SIGLEC10,SLC17A7,PPP1R3F,FZD3,RTN4,ADAMTSL3,NETO2,NETO1,RNF146,SOCS4,ST8SIA2,GAN,PRRT4" Drug 3544_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADORA2A,KIAA1324,SPARCL1,AMT,APBA2,CDK13,RUNX1T1,CBFA2T2,LHX2,HOMER3,FAM149A,WHRN,DYNC1I1,CDON,DTNB,PLXNC1,C3orf18,ERBB4,FGF1,BAIAP2,AFF2,ZNF44,SRCAP,ADAM28,LYVE1,LPAR4,AP4S1,PACRG,ADAM22,NNAT,PAX6,NLE1,PPARA,SAMD9,ENOX1,RGS12,RASA3,COA1,ZNF415,RBM26,CLSTN2,ARC,WSCD1,TNS1,CHST5,AMACR,TRO,UBE3A,KCNAB1" Drug 5081_UP Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "NDRG2,ADRA1D,AMPD3,ATP1A3,ATP2B2,MYOM1,BMP7,CACNA2D2,CHRNA4,WHRN,ABCG1,RGS6,VCAN,BRINP1,DTNA,EDN3,EIF4G2,ANKMY1,SYT17,GFER,LYVE1,GLI2,TOX3,GNG4,HNMT,ICA1,PACRG,MAP2,ADAM11,NOVA1,PALM,PDE4B,MAPK10,PTPRB,RASGRF1,RGS4,KCTD17,SH3BP2,FAIM2,KDM4C,DDN,ATP10B,TAL1,SMG6,DNAH7,VGF,MKRN3,SLC17A7,FAM13C" Drug 5806_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "BIN1,APC,SLC4A4,NRP2,CFLAR,ST3GAL5,CAMK2B,RUNX1T1,CCK,B4GALT6,CNR1,MYRIP,CPS1,CRMP1,VCAN,PDE4DIP,ARHGAP24,DCAF8,CDON,EPB41,ERBB2,FGFR1,SEMA4D,FLT1,TRMO,CGREF1,GNG4,MAN2A2,MGAT3,GIT1,CNOT4,PPP2R2B,WDR25,PNMA8A,GSTCD,EMID1,FNDC3A,ELMO2,TMCC1,CLASP2,PHF24,THRA,RIMBP2,TPM1,TRIO,VIPR2,WIPF1,REEP1,MAP3K12" Drug 3978_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "NME5,DNAH17,MARK4,SCAPER,MTMR3,CFAP410,RUNX1T1,CBFA2T2,TAOK2,CLTB,CSF1R,GREB1,CYBB,DAPK1,RUSC2,EDNRA,FGFR1,FGFR3,AFF2,FAM49B,ADAMTS13,ATXN2L,KCNJ5,KCNN1,KIF5A,ADAM22,MSR1,MX1,NF1,SLC11A2,PPP2R2B,CEP41,MAPK7,PTPRD,FBXW7,SEMA6D,SLC2A5,SP4,PEG10,ARHGAP26,ATP10B,PHLDB1,ARC,SYN2,CRTC1,SLC35G2,VIPR2,SPHK2,EMSY" Drug 5090_UP Bufexamac [2438-72-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "AGT,SEMA6A,ALK,SYT13,TRMT9B,KSR1,ST3GAL5,MTMR3,GYG2,DLGAP1,CRLF1,AKAP7,SH2B1,ABCG1,AATK,SUSD5,ARHGEF4,MFAP3L,MTSS1L,AGAP2,EFCAB2,FYN,MSL3,ELOVL5,ICA1,PACRG,MAPT,MMP16,ADAM22,PALM,PDE4B,RETREG1,PLXNB1,SNRK,PTPRH,ZSCAN2,RGS12,EMID1,FRMPD1,SLA,SPTAN1,ZBTB43,SYT1,AP4E1,TK2,LAT2,MKRN3,REEP1,GAN" Drug 3557_UP Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "NDRG2,AMPH,APBA2,ATP1A3,N4BP2L1,BACH1,ARHGAP33,CHRNA4,PDE4DIP,CNTNAP2,SPOCK2,EDNRB,CNNM1,TENM1,C3orf18,ERCC2,FHL1,SEMA4D,FLNC,CAMKK2,FYB1,GAD1,GPER1,GPR37,ELOVL5,MAP2,MID1,GIT1,MYO7A,NF1,NOVA2,NTRK2,NTRK3,LRRN3,RELN,C1orf54,KHDRBS2,RGS12,EMID1,RTN1,SEMA6D,FAM214B,UNC5B,ATP10B,WSCD1,SZT2,TNS1,PIK3R5,CHST5" Drug 3898_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "NDRG3,KIAA1324,SPARCL1,ALCAM,LTBP4,BEGAIN,CDC14B,RGS20,SLC4A4,NRP2,SCAPER,CFAP410,USP2,RCBTB2,CLTB,CRMP1,DCAF4,MFAP3L,RUSC2,EDNRA,RASGRP2,IGSF6,REEP2,FGFR1,PDLIM5,STON1,TJAP1,JAK2,KIT,MEF2C,MIA2,PCBP3,CEP41,ZSCAN32,NUDT11,CARF,RPS6KA2,KCNIP1,OGDHL,PEG10,CDK19,THSD1,SYNE1,DOCK9,TRO,UCHL1,FLRT2,LAT2,SLC30A3" Drug 5085_UP Iodipamide [606-17-7]; Up 200; 3.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "CDK13,RASL11B,ATP6V0A1,ST3GAL5,BAIAP3,RUNX1T1,ARHGAP22,CNTN1,AKAP5,MYRIP,CRY2,FAM131B,SEMA3D,MRNIP,COQ7,FGF1,DCTN2,FYB1,GAA,ZNF44,DENND2A,SIGLEC8,SPACA9,SYNPO,ITGA7,ADAM22,MX1,NF1,NOVA1,NTRK2,PFKFB4,PRPH,PTCH1,PTPRH,PTPRN2,RIPOR1,TMEM231,RPS6KA2,RPS20,ZNF821,SLA,BTBD7,SNCA,KDM4B,DOCK9,ZNF34,VIPR2,LAT2,SPHK2" Drug 959_DN "N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ABR,MTUS1,APOC1,STX16,SYNJ2,C5,PLEKHB1,STOML1,QKI,ARMC8,CREM,FBXL5,PARD6A,DTNA,PHF20L1,MBNL2,MRNIP,EZH1,SRCAP,CNTRL,HSF2,KCNF1,MAP4,MBNL1,MPP2,NF1,CNOT4,NRCAM,SETD4,OXTR,PIK3R1,PLXNB1,MBOAT7,CEP97,CLIP1,FUZ,FNDC3A,ABLIM3,PEX26,DOP1A,DIP2A,VPS13A,SIN3B,AP4E1,KAT6B,HIRA,XRCC4,HPS4,PHTF2" Drug 4494_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADORA1,APAF1,EPB41L5,PPP4R4,ARRB1,CDK13,ATP1A3,BMP7,ST3GAL5,KCNAB3,CNR1,CSF1,CTH,C2CD2L,CELSR3,APC2,DLC1,FGF13,FYN,NEU3,TDRKH,GRIK5,FAM69A,L1CAM,LIFR,LSS,ADAM22,NPTX2,PDE4A,STRN3,PTPRH,ZSCAN2,ZMAT4,RFX2,RNASEL,KCNIP1,FRMPD1,HKDC1,PKNOX2,RBM34,SOX15,ZHX3,TCF4,TRIM2,PCDHA5,AP4E1,LMF1,NAV3,KCNAB1" Drug 2763_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "C1QTNF1,DDO,SEMA4G,MARK4,N4BP2L1,KALRN,HAP1,SLC16A4,LHX2,CNTN1,SPOCK2,DBT,DMD,SLC12A6,EDIL3,PLXNC1,EIF4G2,C3orf18,FGFR3,FHL1,ALDH1L1,ADAMTS13,GUCY1B1,ATXN2L,ELOVL5,IRF8,IGF1,IL6ST,MSR1,TAGLN3,ELOVL2,CCDC40,KCNIP1,RASA3,ASAP3,FAM214B,SLC9A5,LIMCH1,SYT5,WSCD1,DICER1,FLRT2,VIPR2,LAT2,XRCC4,ZNF45,NT5M,PHTF2,DPF3" Drug 6519_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADCY6,AK2,SYT13,APC,APOC1,NUMB,ADAM15,SYNJ2,CAMK2G,DLGAP1,EPS15L1,SULT4A1,HOMER3,CNTNAP2,RUSC2,DMPK,RCAN1,EDN3,HEYL,TNK2,FHL1,FYB1,GCNT2,GPER1,SLC2A6,HAS2,MBD1,MSI1,ADAM22,MYO7A,RETREG1,NECAB2,PPP2R2B,PPP5C,PTPRB,TRIM68,KCTD17,TCP11L1,SNCA,DDN,TRIM2,HIF3A,TEK,TK2,VIPR2,WIPF1,LAT2,SLC30A3,PLSCR4" Drug 5810_UP Diazoxide [364-98-7]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "AGT,C1QTNF1,SEMA4G,KIF1A,CFLAR,CAMK2B,ABCG2,CNTFR,ARMC8,GIT2,DBT,DNAH9,DRP2,EGFR,ZNF589,FYB1,SIGLEC8,SYT17,SRCAP,GPER1,CNTRL,GSTM5,RASSF8,IFI16,FAM69A,KIF2A,KIT,MAPT,TAGLN3,NEK1,CNOT4,P2RY1,RAD51D,SH3TC2,CCDC25,RPS6KA2,AMBRA1,FBXO11,FNDC3A,KDM4D,MYH15,TMCC1,KDM4C,SYP,SLC19A3,VIPR2,LAT2,ZNF74,HPS4" Drug 5534_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "RALGAPA1,ADRA1D,OGT,APC,GAS7,AQP6,CDC14B,PLA2G4C,AZGP1,SCAPER,MTMR3,CACNA1G,CFAP410,CA4,CALB1,CRYM,CSF1,LRIG1,SIPA1L1,SLC12A6,PLXNC1,ZNF589,FHL1,SCARA3,GATM,TOX3,GPER1,BTN2A1,HNMT,DHX35,MAN2A2,NF1,STRN3,LRP12,MBOAT7,MAPK7,ELOVL2,RASGRF1,GTDC1,STUM,SH3BP2,PKNOX2,SOX15,STX1A,SMG6,OBSL1,CABIN1,TRO,ZKSCAN5" Drug 3286_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADCY6,ADORA1,SEMA7A,APBA2,APC,ALDH7A1,CFLAR,SYNJ1,CBFA2T2,FOXN3,PICK1,CNTN1,CSF1R,RIMS2,DCAF8,MAML1,SGSM2,DTNB,ELN,SPEG,ZNF589,AFF2,KHDRBS3,GRM8,ATXN2L,JAK2,KHK,LMO2,NOVA1,PLTP,MAPK7,GRAMD1C,C1orf54,RPS6KA2,ASAP3,SLC9A5,KIF13A,ZSWIM8,KIAA1107,DMXL2,RPGRIP1L,OBSL1,CRTC1,R3HDM1,TNS1,PLPPR2,NDRG4,DNALI1,HPS4" Drug 3892_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "C1QTNF1,ALCAM,GAS7,CDC14B,DNAH17,CHRD,SLC4A4,ATP2B2,N4BP2L1,GYG2,CAMK2B,SLC16A4,FOXN3,TPP1,ARHGEF6,DTNB,EDIL3,F5,SIGLEC8,MSL3,GRIK5,GRIN2C,GUCY1B1,NXPH3,IRF8,TJAP1,KCNJ5,KCNN1,AFDN,FXYD7,NNAT,OPRL1,GDPD2,SNRK,CRTAC1,RGS4,EMID1,KCNIP1,HKDC1,PREX2,SLC11A1,NFASC,CLSTN2,DOCK9,CRTC1,ICAM5,VIPR2,ZFP37,KCNAB1" Drug 4612_UP Capsaicin [404-86-4]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ASPHD1,ACHE,SPARCL1,SEMA7A,CDC14B,CACNA1G,CFAP410,SEPT7,TAOK2,FAM149A,SH2B1,PDE4DIP,ARHGEF4,MFAP3L,C2CD2L,SV2B,DRP2,DTNA,EDN3,EDNRA,EIF5,AGAP2,NSG1,SIGLEC8,GNAL,ELOVL5,IL6ST,KCNJ5,SMAD1,MATN3,AFDN,MMP16,NEFM,NF1,FA2H,PPP5C,PRKAR1B,PRPH,RGS12,IZUMO4,ZNF423,NFASC,CLSTN2,PHLDB1,MCF2L,FLRT2,WIPF1,KCNAB1,AP3B2" Drug 3997_UP Cefotetan [69712-56-7]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADD2,ADRA1D,SPARCL1,CDC42BPA,PPP4R4,PTCH2,CFLAR,SYNJ1,FUBP1,CAMK2B,CD86,CBFA2T2,PLEKHB1,TPP1,LY86,AKAP6,AKAP5,ERC2,RIMS2,DCAF4,DTNB,NRN1,OLFM1,PRELID3A,ELOVL5,IRF8,IL6ST,ITGA7,MMP16,P2RY13,TREM2,NLE1,PPP2R2B,ELOVL2,PTPRN2,BEND5,GAL3ST4,MRAS,PLCB1,ASTN2,MCF2L,PCDHA5,VIPR2,LAT2,MAP3K12,SLC17A7,KCNAB1,PHTF2,DPF3" Drug 6749_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "AGT,NME5,LTBP4,PTCH2,SLC4A4,ADGRB2,SYNJ2,IL33,CFAP410,CACNA2D1,SOCS6,ASIC3,ARHGAP22,CNTFR,CNTN1,CRY2,DAPK3,C2CD2L,DRP2,ECM2,SCML2,CORO2B,BAIAP2,DCTN2,EFCAB2,PRELID3A,KCNMB4,CACFD1,GRM8,HNMT,MX1,NF1,NOVA2,PDE4A,RETREG1,CCDC40,ENOX1,ZNF821,CPEB3,SLC4A3,SLC8A1,ZHX3,SP4,KDM4C,ATP10B,ST5,TPM2,HIRA,TFIP11" Drug 6612_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ACHE,C1QTNF1,LTBP4,EPB41L5,APOC1,BMPR1B,SYNJ1,CACNA2D1,HAP1,SYNGR3,DCLK1,RAB33A,CREM,ABCG1,LRIG1,DGKG,DBT,C2CD2L,DTNA,IRAK4,SPEG,ZNF589,CPLX2,ZNF276,GRIK5,PADI2,ATXN2L,ITPKA,KCNH2,KIFC3,LMO2,MMP17,NPR2,PALM,PPARA,CEP41,ELOVL2,PTN,PTPRN2,ZSCAN2,MARCH1,FBXW7,SH3BP2,ASAP3,WDR37,TMCC1,PHLDB1,FLRT2,DPF3" Drug 5817_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADCY6,BRAP,BIN1,CDC14B,SEMA4G,SLC4A4,ATP2B2,KIF1A,C5,CHN2,HAPLN1,SUSD5,HDAC9,CDON,CELSR3,STX2,ETV1,OGA,FYB1,TRAF3IP2,GLYR1,LPAR4,MAP2,MAPT,GIT1,SLC11A2,NLE1,PLCD1,POLG,PPP5C,BEND5,CCDC25,FBXW7,SBF1,ZNF821,NLGN1,SLC11A1,SLC14A1,ELMO2,FAIM2,TSNAXIP1,ASTN2,TRIM2,TLR4,TPM1,WIPF1,ZNF24,MKRN3,TFIP11" Drug 3306_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADRA1D,C1QTNF1,SPARCL1,CDC42BPA,APBA2,APC,ST3GAL5,CACNA1I,BAIAP3,CFAP410,CAMK2G,CBFA2T2,SEPT7,FOXN3,ASIC3,TAOK2,TPP1,WHRN,MAMLD1,EGR3,EIF4G2,PTK2B,OLFM1,GAD1,GLYR1,KCNB1,KIT,TAGLN3,MX1,ZNF862,CEP41,MAPK10,PTN,KCTD17,SLC6A8,SLC11A1,MYH15,DOK5,ARC,SYT5,WSCD1,TCF4,ZEB1,PCDHGA10,TIAM1,TRIO,WIPF1,KCNK12,KAT6A" Drug 6675_DN Suloctidil [54063-56-8]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ADD2,NME5,ALK,APAF1,APC,HOMER3,IQCK,ABCG1,PDE4DIP,RASSF2,GIT2,EDIL3,CELSR3,PLXNC1,DENND4A,ETV1,RRAGB,SCML2,ZNF589,FGFR1,ANKFY1,DENND2A,B4GALNT1,USP19,KCNMB4,GPD2,GPER1,IL6ST,TM6SF1,MIA2,NF1,PIK3R1,PLXNB1,GRAMD1C,SNRK,PTCH1,ELOVL2,FAM184A,SBF1,ATXN7,ASAP3,PREX2,BTBD7,TMEM121,NACC2,KLC2,XRCC4,EMSY,SEMA3B" Drug 3614_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "C1QTNF1,SYT13,AMPD3,AMPH,BIN1,APAF1,MARK4,ATP2B2,ST3GAL5,CFAP410,CACNA1A,CACNA2D1,CALB2,USP2,HOMER3,HDAC9,RASSF2,HEPH,SPOCK3,DNAH9,STX2,APC2,FGF12,FHL1,NSG1,ALDH1L1,LILRA2,INPP5B,LSS,ZNF862,NF1,NOVA2,PALM,ELOVL2,CCDC40,C1orf54,RASA3,SLC11A1,NMNAT2,IZUMO4,SPTAN1,POGZ,PHLDB1,HIF3A,TIMP4,SPHK2,ZNF154,PRDM10,TIGD6" Drug 4427_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "SEMA7A,KCNAB2,FAM131A,CDC14B,ASGR1,BACH1,GYG2,HAP1,SYNGR3,CACNA2D2,AKAP5,NRG2,PDE4DIP,MFAP3L,PLPPR4,SEMA3D,F5,ERAP1,LILRA2,FAM107A,PADI2,IL6ST,ITGA7,KCNH2,KHK,MMP16,NF1,NPTX1,NRCAM,NTRK3,PCDH9,PIK3R1,PURG,PRKCB,PTCH1,SLC25A36,PNMA8A,ZNF334,KDM4B,ZHX3,ZC3H13,SYP,MCF2L,KLHL4,CA14,HIRA,SPHK2,EVI5,NLRP3" Drug 4381_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "ALCAM,APLP1,APOC1,ALDH7A1,CAMK2B,ARHGEF2,SULT4A1,CNR1,ENTPD4,ARHGAP24,INTS1,EXOG,CDON,ELN,ERBB2,AFF2,CAMKK2,SIGLEC8,GPER1,KCNJ5,KCNN1,NTRK3,PCDH8,PLCD1,PLCL1,PPARA,MINDY2,PTPRN2,RNASEL,RPS6KA2,EMID1,KCNIP1,ZNF821,ASAP3,CPEB3,FNDC3A,PREX2,PKNOX2,BTBD7,LIMCH1,UNC5B,WSCD1,SLC35G2,R3HDM1,TNS1,UCHL1,VIPR2,SLC17A7,AP3B2" Drug 4491_UP Althiazide [5588-16-9]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.12E-07 4.92E-03 1.15E-05 1.29E-04 49 199 "SYT13,APBB2,PPFIA3,CDK13,ADAM23,NRP2,BMP7,FUBP1,KALRN,CD86,CDO1,CHN2,FAM189A2,NCOR2,LRIG1,PYGO1,MAML1,MFAP3L,DMPK,SHANK1,DUSP9,NCALD,NEU3,MYO7A,ZNF862,NFIX,NTRK2,PCSK1,NLE1,VPS13C,PTCH1,ZSCAN32,PTPRB,RGS3,SALL1,DZIP1,PKNOX2,SLC11A1,ZNF334,IZUMO4,ATP10B,TROVE2,EXOC7,DOCK9,TRIO,VIPR2,SLC17A7,KCNAB1,GAN" Drug 6972_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-07 4.95E-03 1.15E-05 1.30E-04 45 176 "NME5,APAF1,MARCH3,BMP7,ST3GAL5,SCAPER,RAB29,CLGN,AKAP12,ARHGEF10,PDE4DIP,ARMCX2,JAKMIP2,OPTN,MBNL2,STX2,FYN,RAB40B,STON1,FAM69A,INPP5B,MAP4,MAPT,MPP2,MXI1,SERPINI1,PKIA,PRPH,PTCH1,FBXW7,SH3GL3,WDR47,ELOVL4,RGL1,STXBP1,TACC1,MCF2L,TRIM2,HEY1,BEX4,NPL,RUNDC3B,ZNF45,REEP1,ITM2C" Drug 5255_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.29E-07 5.64E-03 1.30E-05 1.46E-04 48 194 "ASPHD1,NME5,AK2,SEMA6A,APBA2,EPB41L5,CFAP410,CA4,CLGN,FOXN3,HOMER3,CNTNAP2,MFAP3L,DTNA,HIPK3,FEM1B,ING4,HSD17B14,EZH1,SCML2,KAT8,FGF13,BAIAP2,FHL1,MSL3,GNG4,GPER1,GPR37,CACFD1,RASSF8,KIF5A,MAPT,MPP2,ADAM22,NPTX1,P2RY1,PCDH9,RETREG1,PPP5C,CCDC25,TCP11L1,CXXC4,SNCA,TROVE2,TBCEL,WSCD1,SSBP2,EPM2A" Drug 2993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.29E-07 5.64E-03 1.30E-05 1.46E-04 48 194 "ABHD6,NDRG2,SEMA6A,BIN1,ST3GAL5,HIP1R,RAB26,CPS1,PDE4DIP,DOCK4,GPRASP1,GSDME,TMCC2,HIPK3,SRPK3,ETV1,TLR7,TBC1D16,FHL1,FYB1,GAD1,INPP5K,GATM,ADAM28,PCDH17,STON1,SCIN,ITGA7,KHK,MEF2C,SERPINI1,PLCL1,PPP2R2B,PRKAR1B,TMEM255A,FAM184A,DOP1A,ELOVL4,RGL1,STXBP1,DNMBP,ADGRL3,TBCEL,PCDHGA10,SSBP2,CLIP2,KLC2,FZD3" Drug 7538_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.29E-07 5.64E-03 1.30E-05 1.46E-04 48 194 "NME5,PKP4,APBB2,APC,RGS20,CDK13,ADAM15,SPAG9,CBFA2T2,PLEKHB1,TBC1D5,MATR3,GIT2,DYNC1I1,FCF1,YAF2,EGFR,ETV1,RRAGB,ZNF589,FHL1,FLT1,GPD2,BACH2,INPP5B,LIG4,MBNL1,MYO6,NF1,SETD4,OCRL,PPP5C,BCAS3,CNTLN,RAD51D,GSTCD,PEG10,SS18,NXT2,SATB2,TRIM2,KAT6B,LAT2,ZNF45,ZFAND5,SEMA3B,MPPE1,KAT6A" Drug 3799_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.29E-07 5.64E-03 1.30E-05 1.46E-04 48 194 "ADORA1,C1QTNF3,LTBP4,TRMT9B,APAF1,ADGRB3,RGS9,NRP2,CLDN10,CPNE6,DBT,DMPK,HS3ST2,SEMA3D,CALCRL,OLFM1,PDLIM5,GALC,IQGAP2,GPR162,LYVE1,STON1,ICA1,KCNN2,ADAM11,KITLG,NCAM2,NPTX1,P2RX7,PALM,PDE4A,C19orf57,POU6F1,RGS3,SH3BP2,CNKSR2,PKNOX2,SLC11A1,ZC3H13,SSTR1,SYT5,PCDHGB6,CRTC1,DNAH7,ZFPM2,ICAM5,CA14,SEMA3B" Drug 5735_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "AP2A2,AGT,SEMA7A,PKP4,APBB2,CDK10,MARK4,PTCH2,ST3GAL5,LDB2,ABCG2,HOMER3,WHRN,DAPK3,SPOCK2,BRINP1,DBT,ELMO1,ECM2,HIPK3,PLXNC1,CDKL3,FGF1,FGF12,ALDH1L1,LILRA2,C2orf72,INPP5B,KIT,MAPT,MATN3,MX1,NF1,NOVA1,PALM,PDE4D,PFKFB2,LRRN3,MAPK10,PTN,DZIP1,PKNOX2,ZNF334,ZC3H13,SPTAN1,IQSEC2,SYN2,CDK20,SSBP2" Drug 5521_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "CDC14B,PLA2G4C,MYRF,CAMK2B,CAST,EPS15L1,QKI,ENTPD4,CRMP1,RIMS2,CYBB,MYEF2,MFAP3L,TMCC2,VPS13B,KAT8,FGF1,OLFM1,DCTN2,TPK1,KCNB1,KHK,IPO5,MAN2A2,MSR1,ZNF862,CYTL1,GDPD2,PTPRE,ZDHHC14,ROBO1,RPS6KA2,SLA,SLC2A5,KANSL3,LIMCH1,ERC1,SPTAN1,THSD1,STX1A,TAL1,WSCD1,KIAA0930,HEY1,CABIN1,ZKSCAN5,VGF,MAP3K12,SLC17A7" Drug 5804_DN Lidoflazine [3416-26-0]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "PDE8B,ALDH7A1,RAB29,LARGE1,PLEKHB1,AKAP7,SLC4A8,ABI3BP,PDE4DIP,PHF14,DPH1,EIF5,FER,SEPT9,SRCAP,MSL3,TDRKH,TJAP1,KIF2A,MAP4,LYRM9,CCSER2,NLE1,MAPK7,PRPH,SAMD9,APTX,SH3TC2,FAT4,ZNF671,RPS6KA2,SUPT20H,AMBRA1,FBXO11,SPTAN1,TROVE2,CEP68,PHLDB1,SYN2,MCF2L,KIAA0930,DNAH7,TIAM1,UGT8,VIPR2,LMF1,ZNF74,NAV3,KAT6A" Drug 2224_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "BIN1,FAM131A,ALDH7A1,N4BP2L1,ADAM23,ADGRB2,LDLRAD4,CACNA2D1,CAMK2B,RHBDL1,CDH2,ASIC3,QKI,WHRN,ABI3BP,RCHY1,SNCAIP,VCAN,SPOCK2,HIPK3,MBNL2,SPEG,DLC1,OLFM1,FGFR3,FHL1,HPCAL4,HPGDS,GNAO1,STON1,C2orf72,IL6ST,ITGAM,SMAD1,MAN2A2,PCBP3,P2RY1,PPARA,ELOVL2,ASAP3,ST6GAL1,PPP4R3A,CCDC88A,KIF13A,IZUMO4,ST5,AP4E1,DNALI1,SLC17A7" Drug 4447_UP nordihydroguaiaretic acid; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "ANK2,BACH1,PROM1,CA12,HAP1,CH25H,CBS,CHRNA4,RAB33A,NRXN3,ABCG1,CSF1,EGR3,FGF1,FYB1,ZNF44,GATM,ALDH1L1,CYP46A1,ADAM28,GLI2,GNAO1,TDRKH,LPAR4,CACFD1,KCNB1,KCNN2,MARK1,MMP17,ADAM22,NELL2,NPTX1,PFKFB2,PLXNB1,PTPRD,FAT4,RGS12,SALL1,CNKSR2,KANSL3,PKNOX2,ZNF334,DOCK9,HIF3A,TRIO,AMACR,TRO,FAM13C,NLRP3" Drug 3044_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "ADD2,SEMA6A,DDO,LGR5,ARHGDIG,ATP2B2,MPDZ,BMP7,CACNB4,HAP1,TAOK2,NRXN3,PCYT1B,HAPLN1,SUSD5,PDE4DIP,SNPH,DAPK3,MFAP3L,EDN3,SRPK3,ELN,VPS13B,EPHB1,ANKMY1,OLFM1,FLT1,SIGLEC8,ALDH1L1,MSTN,ZNF276,PRUNE2,PCLO,SCIN,MAP4,AFDN,MYH3,MYT1,NFIX,PRKAR1B,PTPRN2,RNASE1,SLC11A1,DBNDD2,ATP10B,ASTN2,TACR1,SLC35G2,TK2" Drug 7007_UP Artemisinin [63968-64-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "ARHGDIG,BAIAP3,CA12,HAP1,FOXN3,PLEKHB1,ENTPD4,AKAP12,CRY2,CSF1R,SIPA1L1,DGKG,ELMO1,CELSR3,ING4,FER,FUT9,ZNF44,DISC1,GLYR1,LPAR4,CNTRL,CACFD1,GRM8,HNMT,ITPKB,LSS,MAP4,GIT1,NF1,PPARA,PRODH,SAMD9,RASGRF1,ZMAT4,GTDC1,SBF1,LIMCH1,SNCA,DOK5,ZNF423,PHLDB1,VPS13A,PLCB1,TRIM2,TNS2,R3HDM1,PLPPR2,KAT6A" Drug 3878_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "NDRG2,ALCAM,BIN1,PPFIA3,PRX,PDE8B,SLC2A11,SCAPER,MTMR3,CAMK2B,SEPT7,SOCS6,CRMP1,RASSF2,SPOCK2,SHANK1,FER,FGF1,PDLIM5,CSDC2,GLYR1,GRIK5,KCNJ5,KCNN1,SMAD1,KITLG,PDE1C,LRP12,MINDY2,LRRN3,MAPK7,C1orf54,GAL3ST4,CARF,RPS6KA2,EMID1,ZFP2,EPN2,FAIM2,KDM4B,TSPYL2,TBCEL,CRTC1,DICER1,TNS1,LMF1,KCNK12,SLC17A7,KCNAB1" Drug 5445_UP Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "ADD2,AP2A2,ADGRF5,APAF1,PPP4R4,RGS20,ATP1A3,SLC2A11,ADGRB3,CACNA1I,CACNA2D1,CD86,SYNGR3,ARHGEF2,NCOR2,CSF1R,INTS1,EDIL3,HIPK3,EGFR,IRAK4,ING4,ELN,IGSF6,FAM49B,PRELID3A,ZNF44,ERAP1,ALDH1L1,SRCAP,GPD1,SPACA9,GUCY1B1,C2orf72,KCNJ16,KCNQ3,KIT,MAP4,MAPT,MID1,ADAM22,MSR1,NF1,NOVA1,TRHDE,KCTD17,SLC9A5,ZHX3,KCNAB1" Drug 5532_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "AGT,SEMA7A,PPFIA3,SEMA4G,PRX,DNAH17,CA12,ARHGEF2,CLGN,CRLF1,CHN2,STOML1,AKAP7,C2CD2,CSF1,ARHGEF10,GSDME,SLC12A6,HEYL,MBNL2,CDKL3,FGFR1,FHL1,ERAP1,KHK,LIG4,NF1,PDE4D,PDPK1,SERPINI1,NLE1,STRN3,LRP12,PPARA,RPS6KA2,SCN2B,SEC14L1,SLC2A5,KDM4C,ARHGAP26,CEP68,KIAA0930,CRTC1,TK2,LMF1,LAT2,KCNK12,MKRN3,PHTF2" Drug 1524_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-07 5.80E-03 1.30E-05 1.47E-04 49 200 "AK2,TRMT9B,APC,APOC1,ATP6V0A1,ADAM23,NRP2,CFLAR,SYNJ2,SCAPER,HAP1,ARHGAP33,ASIC3,PLAA,HOMER3,WHRN,SLC4A8,CNTNAP2,DOCK4,RASSF2,MFAP3L,RCAN1,FRY,EGFR,SRPK3,ERCC2,FGFR1,ATP2C1,ADAMTS13,GRIK5,HNMT,HSF2,MAP4,NF1,NPTX2,SLC25A23,MAPK10,PRODH,PRPH,CEP97,ARHGAP26,ZBTB43,CRTC1,HEY1,BEX4,TNS1,TRIO,MPPE1,KAT6A" Drug CID000000892 myo-inositol Stitch 1.50E-07 6.58E-03 1.47E-05 1.65E-04 141 812 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,AMPH,NT5C3B,ARRB1,ARRB2,ATP2A2,ATP2B2,ALDH7A1,SYNJ1,SYNJ2,BTK,MTMR3,MTMR2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2B,SPAG9,CCK,P2RX6,ARHGEF1,CD38,DGKI,LRBA,CACNA2D2,CHGB,PLEKHB1,CHRNA4,CLTC,HOMER3,CSF1,RGS6,PLCXD3,DGKB,DGKG,IP6K1,PITPNC1,SNAP91,DNM1,DNM1L,EDN1,EDN3,EDNRA,EDNRB,EGFR,RASA4,ERBB2,ERBB4,PTK2B,FCGR1A,FCGR3A,FGF1,FGFR1,IP6K2,AGAP2,FOXO3,PSD2,ATP2C1,FYN,GAA,IP6K3,IQGAP2,GNAL,GNAO1,ADAP1,LPAR4,MCHR1,GRB10,PLCD4,GRM2,GRM8,GSN,SLC2A6,MYLK2,IGF1,INPP1,ITPKA,ITPKB,LIG4,MATK,MBP,KITLG,MMP17,P2RY13,NF1,NPY,OCRL,OXTR,P2RX7,P2RY1,PDPK1,PIK3C2A,PIK3R1,PKD1,PLCB2,PLCD1,PLCL1,POLR2F,PPP1R1A,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTH1R,RGS3,RGS4,RYR3,MAPK12,SMPD3,RASA3,SLA,TEX2,SS18,PLCB1,TACR1,TBL1X,TCF4,PIK3R5,PDSS1,TSC1,FLRT2,VAV1,VIPR2,P2RY12,RICTOR,PLD4" Drug 4643_UP Iohexol [66108-95-0]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "ADCY6,ADD2,AP2A2,MTUS1,SEMA7A,ARRB2,KSR1,C5,CACNA2D1,ARHGAP33,SOCS6,CHN2,RAB28,TPP1,RAB26,CSF1,RGS6,VCAN,PDE4DIP,PLPPR4,EDNRA,RASGRP2,ZNF589,PRRC2B,KIT,TAGLN3,CNOT4,PLCD1,PTK2,RFX2,TRAPPC13,FUZ,FBXO11,ANKRD6,ABLIM3,FAIM2,ZHX3,ARHGAP26,SYT1,COBL,ASTN2,KIAA1107,TBCEL,TCF4,SSBP2,UGT8,KCNK12,NAV3" Drug 6689_DN Biotin [58-85-5]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "CDC14B,MARK4,KIF1A,ST3GAL5,CACNA1A,KRIT1,ABCG2,ARMC8,BAG4,VCAN,SGSM2,CHRDL1,FAM13A,COQ7,CDKL3,FGFR1,AFF2,OGA,FYN,B4GALNT1,POLL,GNG4,LPAR4,ICA1,KCNN1,SCAMP5,PALM,PIK3R1,RETREG1,PTN,ZSCAN2,NEK11,RXRA,ASAP3,FBXO11,NLGN1,MYH15,SPTAN1,IQSEC2,SUPT5H,DOCK9,TK2,WIPF1,WNT7A,XRCC4,SH3GLB2,KCNAB1,DPF3" Drug 5240_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "NDRG2,TRMT9B,APAF1,APBB2,GAS7,KIF1A,BCL7A,CFLAR,CA4,ARHGEF2,ARHGAP33,FAM189A2,CRY2,SIPA1L1,GREB1,DCAF8,SLC12A6,EDN1,ING4,ZNF589,FER,FGF13,PCDH17,MSL3,STON1,JAK2,KCNJ5,KIF5A,MBD1,MEF2C,ZNF862,NF1,MTRF1L,SAMD9,ZCWPW1,KHDRBS2,RGS12,SH3BP2,LIMCH1,KDM4B,KDM4C,ASTN2,WSCD1,PCDHA5,UCHL1,XRCC4,ITM2C,FAM13C" Drug 3942_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "ABHD6,NME5,LTBP4,KCNAB2,ARRB1,SYNJ1,GYG2,CLGN,B4GALT6,CNTFR,ARMC8,NECTIN3,DZIP3,RIMS2,MFAP3L,EXOG,DUSP9,CELSR3,ERBB2,VPS26C,ANKMY1,FGFR3,SYNCRIP,GALC,INPP5K,CNTRL,ADAMTS13,INPP1,KCNH2,KCNN2,ADAM22,LYRM9,LRP12,PRPH,RGS12,TCP11L1,SIRT2,PDZRN3,CDK19,ATP10B,TACC1,IQCE,PCDHA6,BEX4,TRIO,ZBTB14,ZNF24,MARCH8" Drug 2748_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "ABHD6,AK2,APC,EPB41L5,ARRB1,CFLAR,MTMR3,MAGI1,PLEKHB1,CREM,NCOR1,ABCG1,CSNK1E,LYPD1,VPS13B,NCALD,VPS26C,ZNF589,IQCG,OGA,DISC1,INPP5K,AHDC1,CACFD1,INPP5B,ITPKB,KCNF1,KCNH2,MAP4,MAPT,KITLG,LYRM9,RETREG1,SBF1,SUPT20H,SLC6A8,ZKSCAN3,LIMCH1,MCF2L,TRIM2,PCDHA6,TMEM121,ZKSCAN5,HIRA,UBE2H,REEP1,EMSY,SEMA3B" Drug 7403_UP Lisinopril [83915-83-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "ABHD6,NDRG2,APBB2,APC,PPFIA3,CFLAR,SCAPER,FOXN3,SLIT2,ENTPD4,PPP6R2,DAPK1,GIT2,DBN1,FBXL5,EIF5,TNK2,MRNIP,F8,FGFR1,SCARA3,GFER,MALT1,COPS8,GRB10,SPACA9,LIG4,AFDN,MSI1,ADAM22,NELL2,PDE1C,PLCD1,FSD1,RIPOR1,RPS6KA2,SEMA6D,CLASP2,PLCB1,IQCE,WSCD1,DOCK9,PARD3,PIK3R5,VLDLR,HPS4,MPPE1,UBE3B" Drug 3718_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "C1QTNF3,AMT,GAS7,APOC1,CDC14B,CDK10,ADGRB2,NRP2,IL33,CACNA1A,CACNA2D2,NCOR2,ABCG1,CSNK1E,CNTNAP2,DAPK3,CHRDL1,DMPK,DTNA,HIPK3,ING4,MRNIP,HSD17B14,FGF1,PRELID3A,SCIN,INPP5B,MAN2A2,MX1,NELL2,NPR2,RETREG1,CEP41,PRKAR1B,WDR25,ZNF821,AMBRA1,ZNF415,ZHX3,KDM4C,DDN,SYT1,TBCEL,SZT2,TK2,LMF1,TRIM9,NT5M" Drug 6065_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-07 6.66E-03 1.47E-05 1.65E-04 48 195 "LTBP4,APLP1,PRX,ARHGDIG,PLA2G4C,RGS11,BAIAP3,CDH2,CDO1,CSF1,PHF14,RIPOR2,FOLR2,PDLIM5,ALDH1L1,SRCAP,RAB30,ADAMTS13,GRIK5,ATXN2L,C2orf72,KCNB1,KIFC3,MATK,MEF2C,MMP16,MYO7A,ZNF862,P2RY1,CDK18,PDE4D,PPP5C,VPS13C,ZNF493,RASGRF1,TRIM68,RGS12,RPS6KA2,SATB1,SLC2A5,PKNOX2,LIMCH1,SPTAN1,SPTB,SPART,R3HDM1,VIPR2,LAT2" Drug 5693_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.61E-07 7.06E-03 1.55E-05 1.75E-04 45 178 "NME5,ST3GAL5,SGCE,BAIAP3,CLGN,AKAP12,PDE4DIP,DOCK4,ARMCX2,FAM13A,STX2,FHL1,HPCAL4,FYN,CYP46A1,RAB40B,TDRKH,STON1,RNFT2,MXI1,SERPINI1,RETREG1,GRAMD1C,PRPH,NUDT11,RPS6KA2,SH3BGR,SH3GL3,WDR47,FAM214B,PKNOX2,OGDHL,SOX15,PEG10,THSD1,TTBK2,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SLC30A3,SLC17A7" Drug 1821_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "APOC1,PPFIA3,CDK10,MARK4,SRSF11,CNOT8,CSF1,DZIP3,ZFYVE16,ZNF337,SGSM2,SCML2,BAIAP2,CINP,CGREF1,INPP5K,SRCAP,DIDO1,GUCY1B1,SHISAL1,KIF2A,KIFC3,MITF,GIT1,ZNF862,PDE1C,FA2H,PPP3CC,SAMD9,PTPN13,NUDT11,MCMBP,MAPK12,LIMS2,SMARCC2,ZBTB43,STX1A,VPS13A,EXOC7,DNMBP,TCF4,ZEB1,CABIN1,LMF1,ZNF32,MAP3K12,HPS4,PHTF2" Drug 5015_DN Benzbromarone [3562-84-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "NME5,SRPX,ARHGDIG,ARRB1,SLC4A4,B4GALT6,CLCN3,STOML1,HOMER3,PDE4DIP,CNTNAP2,FAM169A,DCAF8,CDON,RCAN1,IRAK4,ENO2,STX2,ACSL4,ZNF589,FHL1,ANKFY1,PDLIM5,TXNL4A,RAB30,INPP1,JAK2,KCNN2,ADAM22,ZNF862,NF1,RETREG1,LRP12,PTPRE,RGS12,RNASEL,FBXW7,SH3BP2,CPEB3,FNDC3A,ZBTB43,TRIM2,PCDHA6,VGF,ZNF45,GDPD5,HPS4,KAT6A" Drug 6718_UP Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADD2,AMH,APC,GAS7,ARHGDIG,ADGRB2,BMPR1B,CACNA1I,IL33,CRLF1,CACNA2D2,ARMC8,CRY2,BRINP1,PARD6A,MTSS1L,ZNF44,ERAP1,SIGLEC8,GPR75,STON1,SHISAL1,ITGA7,ADAM22,MSR1,MYO7A,NF1,RGS12,PNMA8A,NEK11,ZFP2,ZNF821,ZFP30,SH3BP2,DZIP1,SLC9A5,IZUMO4,ARHGAP26,LMO3,COBL,TACR1,TAL1,SMG6,PCDHA5,TUBB1,VIPR2,REEP1,ZNF225" Drug 3517_UP Torsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADGRF5,ALK,SEMA7A,APBA2,APBB2,CFLAR,HIP1R,CACNA2D2,AKAP6,HINFP,DAPK1,ARMCX2,SHANK1,DTNA,RCAN2,ZNF589,FGFR1,SIGLEC8,DISC1,GATM,GSTM5,ICA1,KCNJ5,KCNQ3,MSI1,ADAM22,MYO7A,NELL2,PLCD1,PPP2R2B,PPP5C,PRPH,WDR25,CNTLN,FAT4,RGS12,ZFHX4,ST6GAL1,SMARCD3,TSNAXIP1,KDM4C,PEG10,ZNF423,WSCD1,TEK,GPR161,UGT8,WIPF1" Drug 2818_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "NME5,APBB2,APC,GAS7,PPP4R4,MTMR2,GYG2,HAP1,CAMK2G,CLGN,LHX2,FAM189A2,VAX2,SULT4A1,CSF1,MFAP3L,LYPD1,RCAN1,HIPK3,BAIAP2,STON1,INPP5B,KHK,LMO2,SMAD1,MIA2,MX1,ZNF862,NF1,NTRK2,LRP12,MINDY2,FAM184A,GTDC1,SUPT20H,BTBD7,CDK19,ZBTB43,PLCB1,DMXL2,SYNE1,CRTC1,CHST8,SLC44A1,HIRA,WIPF1,ZNF74,DNALI1" Drug 3776_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "EPB41L5,CDC14B,SEMA4G,ADAM23,CBS,ARHGEF1,CBFA2T2,LARGE1,TAOK2,ARHGAP22,RAB28,LY86,PICK1,HAPLN1,PHF14,MFAP3L,EXOG,FEM1B,STX2,FGFR1,DCTN2,SRCAP,POLL,IL12A,MAPT,ZNF862,NDP,NF1,CNOT4,PALM,POLG,PRKAR1B,CNTLN,ACSS3,C1orf54,NEK11,TCP11L1,KCNIP1,ATXN7,ASAP3,FUZ,ATP10B,HIRA,VGF,LMF1,XRCC4,SPHK2,DPF3" Drug 3826_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "NDRG2,ADORA1,LTBP4,ADGRB2,CDO1,NRXN3,STOML1,RAB26,ABCG1,CNTNAP2,DTNB,ELN,EPHB1,EZH1,KAT8,BAIAP2,SEMA4D,AFF2,ZNF44,POLL,GRM2,KHK,KITLG,AFDN,MMP17,GPR85,LRRN3,ZMAT4,RGS12,PNMA8A,EMID1,CSRNP3,PKNOX2,SLC11A1,ZNF667,SNAP25,ARHGAP26,ADGRL3,TBCEL,DMXL2,DOCK9,OBSL1,PCDHA5,HIF3A,TUBB1,LAT2,SLC17A7,KCNAB1" Drug 6607_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ALK,PRX,N4BP2L1,BACH1,FUBP1,CACNB4,CAMK2B,PDE4DIP,ERC2,RIMS2,SPOCK2,MFAP3L,SV2B,ELN,LRRC17,RASGRP2,DLC1,AGAP2,ERAP1,SIGLEC8,CSDC2,RUNDC3A,POLL,PRUNE2,GRIK5,PADI2,ELOVL5,KCNN1,KIF5A,KIT,LAMA2,MAP4,MBNL1,MMP16,PALM,PLXNB1,PTN,PTPRB,KCTD17,FRMPD1,ASAP3,SNCA,SPTAN1,ATP10B,TCF4,SZT2,HIRA,KCNAB1" Drug 2318_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADRA1D,C1QTNF3,SRPX,AMPD3,CDC42BPA,SEMA7A,APBB2,PPP4R4,CRLF1,RCBTB2,RAB33A,CRMP1,CSF1,CTH,RCAN1,HSD17B14,STX2,ZNF589,FHL1,TDRKH,GRIK5,ATXN2L,TJAP1,INPP5B,ITPKB,KCNN1,MMP16,GIT1,ZNF862,NF1,NTRK2,PALM,PPP5C,MAPK7,TCP11L1,FRMPD1,FAM214B,RCOR3,THSD1,SYN2,WSCD1,BHLHB9,CABIN1,VGF,WIPF1,CLDND1,XRCC4,SMIM8" Drug 5947_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADCY6,NME5,LTBP4,SYT13,DOC2A,TRMT9B,BIN1,CDC42BPA,SEMA4G,PLA2G4C,MARK4,BAIAP3,CDH2,CHRNA4,TAOK2,WHRN,COL9A3,NRG2,SOCS5,RIMS2,DGKB,EGFR,ING4,GAD1,DISC1,SRCAP,GNG4,SPACA9,CACFD1,HNMT,KCNJ5,SMAD1,MMP17,RNASEL,NEK11,RASA3,SH3BGR,SPTAN1,SPTB,STX1A,JMJD6,TCF4,TMEM121,TRIO,FAM155A,VGF,NT5M,AP3B2" Drug 1479_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "TRMT9B,BIN1,SLC4A4,ATP2B2,CFLAR,SCAPER,NCOR2,AATK,CSF1,RIPOR2,DAPK3,EGFR,PLXNC1,CALCRL,FGFR1,HPCAL4,IQCG,ERAP1,GLYR1,GRIK5,CACFD1,TJAP1,IL6R,KCNH2,LMO2,AFDN,TAGLN3,SETD4,KCNIP1,NLGN1,SLC2A5,CXXC4,MAPKBP1,RBM34,IQSEC2,POGZ,ASTN2,SYT5,TBCEL,WSCD1,CRTC1,TK2,PIK3R5,CDK20,VIPR2,KCNK12,ZFP37,JPH3" Drug 4991_UP Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "AGT,KCNAB2,APC,GAS7,PPP4R4,RGS20,PDE8B,AZGP1,CFAP410,USP2,ARHGEF1,CHN2,SULT4A1,WHRN,RUSC2,EDNRA,EDNRB,VPS13B,ST3GAL6,GAD1,SIGLEC8,ALDH1L1,SRCAP,POLL,GNAO1,PRUNE2,PRDM5,ITGA7,KCNH2,KCNQ3,MSI1,P2RY1,PCSK5,PLXNB1,KHDRBS2,CNKSR2,SYBU,SLC2A5,SLC6A8,COA1,ATP10B,TMEM121,TK2,CDK20,LMF1,WIPF1,MAP3K12,SEMA3B" Drug 4357_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "AGT,TRMT9B,BIN1,APC,APOC1,LGR5,ADGRB1,CALB1,KALRN,ARHGEF2,CBARP,AKAP5,HDAC9,DAPK1,SPOCK2,CDON,ELN,SPEG,NEU3,TOX3,GPER1,MSR1,NTRK3,PALM,PCDH9,PCSK5,PFKFB2,MTRF1L,MINDY2,SAMD9,MARCH1,PID1,RFX2,RGS4,KLHDC8A,SLC2A5,BTBD7,KIF13A,ZSWIM8,ZC4H2,TBCEL,WSCD1,DICER1,AMACR,UCHL1,KCNAB1,FAM13C,JPH3" Drug 6889_UP AG-012559 [369370-06-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "NDRG2,DOC2A,BIN1,PPFIA3,PRX,CFAP410,CACNA2D1,CACNA2D2,CNOT8,LHX2,STOML1,PHF14,DCAF4,CYBB,RASSF2,MBNL2,APC2,CGREF1,POLL,CNTRL,GRIK5,CACFD1,HNMT,KCNH2,L1CAM,MATK,GIT1,ADAM22,ZNF862,PALM,PDE4A,SLC25A23,LRP12,PRPH,TMEM231,RGS12,ZFP30,SH3BP2,KIF13A,TTBK2,OBSL1,SLC44A1,CHST5,HIRA,LMF1,VSNL1,EVI5,MPPE1" Drug 6061_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADRA1D,ADRA1B,AMPD3,BIN1,APLP1,ARHGDIG,SLC2A11,GYG2,CDH2,TAOK2,ARHGEF6,WHRN,IPCEF1,CNTNAP2,SPOCK2,SRPK3,HSD17B14,RASGRP2,APC2,CORO2B,FYN,GFER,STON1,GPER1,GPR37,GRM8,ATXN2L,ICA1,ITPKB,AFDN,SLC11A2,NECAB2,LRRN3,RELN,CCDC40,RGS12,KCTD17,KCNIP1,PEX26,SLC9A5,LIMCH1,PEG10,JMJD6,TK2,ZKSCAN5,FAM155A,FLRT2,CLIP2" Drug 4958_UP Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "SYN3,NDRG2,NME5,C1QTNF1,LTBP4,APBA2,APC,FAM131A,PPFIA3,SEMA4G,CDK13,SLC2A11,GYG2,BAIAP3,RAB33A,CSF1R,TMCC2,EIF4G2,RASGRP2,ZNF589,FGFR1,SEMA4D,ERAP1,MSL3,GNG4,ICA1,KIFC3,NF1,PDE4B,PFKFB2,PTPRB,KCTD17,KLHL11,RPS6KA2,FRMPD1,FUZ,KANSL3,DOP1A,HECW1,ZC3H13,IQSEC2,CDK19,MCF2L,HIRA,LAT2,KLC2,SPHK2,NLRP3" Drug 3965_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ASIC1,NDRG2,APC,PLA2G4C,MARK4,ALDH7A1,SCAPER,GYG2,FOXN3,B4GALT6,RAB28,CLTB,RCHY1,CSF1,TMCC2,CDON,SLC12A6,RCAN1,EDNRA,DLC1,ZNF589,KHDRBS3,GAD1,USP19,ADAMTS13,GRIK5,KCNN1,KCNQ3,ADAM22,N6AMT1,NEK1,NELL2,NF1,MTRF1L,RNASEL,SEMA6D,SYBU,FAM214B,RCOR3,MAPKBP1,KDM4B,TSNAXIP1,MTCL1,DICER1,SPHK2,KCNAB1,PLSCR4,SENP7" Drug 6000_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADORA1,AP2A2,ADGRF5,C1QTNF3,SPARCL1,CDC42BPA,APC,PLA2G4C,SLC16A4,CBFA2T2,CACNA2D2,NECTIN3,TBC1D5,PARD6A,DTNA,EDN1,EGFR,ING4,PRELID3A,FYB1,INPP5K,PRUNE2,GPER1,HLF,LIG4,PACRG,MAN2A2,MEF2C,AFDN,ADAM22,NTRK2,MAPK7,RELN,CNTLN,KCTD17,KCNIP1,RASA3,SH3BP2,ASAP3,PKNOX2,ZNF423,PLCB1,SZT2,DOCK9,SLC35G2,DICER1,UCHL1,DNALI1" Drug 1214_UP 2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ABHD6,APC,MARK4,STX16,MPDZ,CA12,CHN2,PLEKHB1,CNOT8,CRY2,NCOR2,SLITRK5,PIPOX,FYN,GAD1,IQGAP2,SYT17,GLI2,FERMT2,STON1,DIDO1,GUCY1B1,ICA1,MMP16,ZNF862,NPR2,PCDH9,POLG,WDR25,PTPRB,GAL3ST4,RGS4,ZNF671,SBF1,SUPT20H,PEX26,EPN2,SAMSN1,ELOVL4,PHLDB1,SYT1,COBL,SYNE1,GPR161,HEY1,UGT8,XRCC4,PLSCR4" Drug 5606_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "ADORA2A,AMH,ADAM23,KSR1,CACNA1G,CD86,NRXN3,WHRN,NCOR2,CNTNAP2,RUSC2,SPEG,FGF13,FGFR3,FHL1,GCNT2,LYVE1,POLL,GNAO1,SPACA9,ITGA7,KHK,KIF5A,MEF2C,MN1,ADAM22,NTRK3,PFKFB2,NECAB2,RELN,PTH1R,NKAIN1,BEND5,SUGCT,KCNIP1,FRMPD1,ASAP3,KIF13A,PHLDB1,ADGRL3,HEY1,TRPM2,UCHL1,LAT2,XRCC4,SLC30A3,ITM2C,GJC2" Drug 5831_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-07 7.86E-03 1.65E-05 1.86E-04 48 196 "CDC14B,CDK13,ALDH7A1,CFLAR,KSR1,ST3GAL5,SCAPER,CFAP410,CAMK2B,B4GALT6,HOMER3,ARMC8,HAPLN1,VCAN,SEC14L5,GIT2,KIAA0753,PDLIM5,GNG4,GRM8,TJAP1,KIFC3,ADAM22,LYRM9,SLC11A2,PALM,SERPINI1,PPARA,MINDY2,LRRN3,PTPRE,PID1,SBF1,PREX2,EPN2,FAM214B,ELMO2,SNAP25,TMCC1,HECW1,PHLDB1,IQCE,CRTC1,UBE2H,TFIP11,EVI5,MPPE1,DPF3" Drug 5625_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.83E-07 8.02E-03 1.68E-05 1.89E-04 44 173 "ADRB2,NME5,APLP1,MARK4,ST3GAL5,BAIAP3,USP2,CLGN,WHRN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,FAM13A,SPEG,HPCAL4,FYN,CYP46A1,STON1,MEF2C,MPP2,MXI1,SERPINI1,SEPT4,PRPH,PTCH1,RPS6KA2,SH3GL3,PPM1E,ASAP3,CPEB3,WDR47,FAM214B,PKNOX2,CCDC88A,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug 981_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.83E-07 8.02E-03 1.68E-05 1.89E-04 44 173 "ARNTL,MARK4,ST3GAL5,SCAPER,BAIAP3,CBFA2T2,PDE4DIP,ARMCX2,MBNL2,TAOK3,BAIAP2,FYN,CYP46A1,RAB40B,STON1,RNFT2,PADI2,ACOT7,MITF,NEK1,PCDH9,PDE4A,SERPINI1,PKIA,PRPH,SH3BGR,SH3GL3,PPM1E,WDR47,SLC6A8,SLC22A4,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,REEP1,SLC30A3,SLC17A7,ITM2C" Drug ctd:D003561 Cytarabine CTD 1.98E-07 8.69E-03 1.81E-05 2.04E-04 110 598 "NDRG2,MTUS1,RGS20,MARCH3,ADGRB3,BID,GYG2,CA12,CALB1,CALB2,PRC1,LRBA,MAGI1,CHN1,SLIT2,PPT2,CNR1,CNTFR,COL9A1,SLC4A8,C2CD2,HAPLN1,LRIG1,SLITRK5,MYADM,RASSF2,AIF1L,DBN1,SNAP91,PARD6A,EXOG,EDN1,NCALD,TUBB3,ST3GAL6,FLNC,TPK1,ST6GALNAC3,SARAF,MPP6,FYN,MEGF10,GCNT2,GHR,TNRC6A,STON1,GPER1,CNTRL,GRIA2,SOX21,GUCY1A1,HAS2,KCNN2,MAP2,MATN2,LRP1B,MEIS1,SCAMP5,NELL2,NPY,NOVA1,PAX6,PCSK5,PDE4B,PDE1B,ABCB1,SEMA5B,PLCB2,PLTP,PMP22,LRRN3,PKIA,PRPH,RELN,KLK6,PTH1R,RGS4,ZFHX4,GSTCD,ATP8B4,ST6GALNAC6,RTN1,CCDC112,LRFN5,SEC14L1,GALNT10,SLA,LIMCH1,SNCA,RBM34,SOX3,SPATA7,ZNF423,RGL1,PRRC2C,TCF12,TEK,ZFPM2,TK2,RGMB,TST,FLRT2,WIPF1,GUSBP1,PCDH20,TCEAL7,PRDM8,ADAMTS9,ITM2C,HNRNPA3" Drug ctd:C012568 terbufos CTD 2.06E-07 9.03E-03 1.82E-05 2.05E-04 128 724 "ADCY8,FZD9,ADRB2,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,LGR5,CDK10,ZNF583,KIF1A,ADAM23,NRP2,CD38,LARGE1,ZNF445,UBE2L6,NGEF,LY86,MYRIP,NRG2,CRMP1,CNTNAP2,ERC2,ARMCX2,SV2B,HS3ST2,RGS17,ZNF549,NRN1,ZNF585B,FGF12,AFF2,HHIPL1,FYB1,MEGF10,GAD1,ZNF559,SYT17,NTNG2,LNX1,MCHR1,GRIN2C,GRM2,PTPRT,GSTM5,SOX21,PADI2,FRMD5,HLF,ZNF491,USP51,IRF8,LAMA2,LIG4,MATK,MATN3,MBP,MN1,MYCN,FXYD7,NEFM,NPTX2,NTRK3,CYTL1,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RASGRF1,BEND5,KHDRBS2,RET,FIGN,ZDHHC4,ZNF671,HUNK,CCDC112,SALL1,SCP2,HES6,SEC14L1,GALNT10,FERMT1,ST6GAL1,DZIP1,ELMO2,INAVA,SNRPN,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,SYP,ASTN2,PCDHGB7,NAT16,TMEM121,TIMP4,PRRT1,IL34,RUNDC3B,FLRT2,VLDLR,KCNK12,ZIC1,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PLD4,DNAH10,NETO1" Drug 4199_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "RALGAPA1,C1QTNF3,AMPH,PPFIA4,MPDZ,LDLRAD4,SYNGR3,LARGE1,AKAP5,PDE4DIP,CNTNAP2,PYGO1,DBT,SV2B,CDON,DTNA,HIPK3,AASS,TNK2,ETV1,FGF1,FLT1,PDLIM5,DISC1,ADAM28,TDRKH,BACH2,MMP16,NDP,NTRK2,RETREG1,ELOVL2,PTPRG,RASGRF1,GAL3ST4,KCNIP1,SUPT20H,PKNOX2,LIMCH1,KIF13A,PBLD,TBCEL,RPGRIP1L,DOCK9,PHF24,PCDHA5,TPM1,LAT2" Drug 6514_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "AK2,SYT13,SEMA7A,GAS7,PLA2G4C,N4BP2L1,ADAM15,SYNJ2,LDLRAD4,CFAP410,CA4,USP2,FOXN3,NECTIN3,NCOR2,RGS6,ARHGEF10,VCAN,RCAN1,DTNA,EDNRA,HEYL,SEMA3D,MBNL2,PLXNC1,RCAN2,FHL1,TPK1,PRELID3A,LPAR4,HLF,KCNH2,MSI1,MSR1,PPARA,PPP5C,PTX3,PBRM1,KCNIP1,SBF1,SCN2B,CXXC4,PHLDB1,ARC,ZNF34,HEY1,XRCC4,SLC30A3" Drug 7484_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "BEGAIN,APC,APOC1,SLC4A4,BMP7,SYNJ2,MTMR3,CHN2,TAOK2,QKI,CREM,ENTPD4,PDE4DIP,INTS1,CDON,DTNA,DUSP9,E2F5,PDLIM5,TXNL4A,GNG4,GRB10,ADAMTS13,RNFT2,ATXN2L,IL6R,MAN2A2,KITLG,MKLN1,MPP2,ZNF862,NTRK2,PDE4A,SLC25A23,SMIM7,MINDY2,PRODH,WDR25,RAD51D,FBXW7,ANKRD6,SMARCD3,ZHX3,LMO3,PLCB1,TACC1,TNS2,MAP3K12" Drug 2161_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADD2,BEGAIN,BIN1,RASL11B,GYG2,CA12,THSD7A,CD86,CREM,SH2B1,DAPK3,DBT,GSDME,SPOCK3,EDNRA,CDKL3,TBC1D16,BAIAP2,SCARA3,TMEM8B,ALDH1L1,ADAM28,GFER,PCLO,GRIK5,PADI2,ITGAM,KIFC3,MAP4,MN1,MSR1,SAMD14,ZNF862,PPP5C,MAPK7,PID1,ZCWPW1,RGS12,KLHL11,ZFHX4,SPTAN1,LHPP,SYN2,OBSL1,RUNDC3B,ZKSCAN5,FAM155A,UGT8" Drug 6367_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "FAM135A,OGT,APC,ARRB1,DNAH17,ZSCAN18,SLC4A4,KALRN,CBFA2T2,STOML1,SULT4A1,CNR1,COL9A3,CSF1,CNTNAP2,RIMS2,SNPH,SPOCK2,HEPH,SPOCK3,SNX29,TENM1,ETV1,OLFM1,FHL1,GAD1,ADAM28,GLYR1,KCNMB4,NXPH3,C2orf72,KCNB1,SAMD14,MASP1,RELN,KHDRBS2,SEMA6D,SLC2A5,ARHGEF40,SLC11A1,SNCA,PHLDB1,SYT5,PCDHGB6,SLC35G2,TNS1,OSBP2,LAT2" Drug 3704_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ASPHD1,ADD2,ADORA1,RASL11B,BAIAP3,HAP1,CAMK2B,FOXN3,B4GALT6,FAM189A2,CNTFR,HAPLN1,NCOR2,CSNK1E,SLITRK5,SPOCK2,CHRDL1,DMPK,DTNA,EDN1,FGF1,SEPT9,PCDH17,IL6ST,KCNQ3,SMAD1,MAN2A2,MAPT,ADAM22,TAGLN3,NPTX1,PDPK1,MAPK10,PTN,PTPRB,PTPRH,FAM184A,KIRREL1,DZIP1,RBM34,TSNAXIP1,UNC5B,HIF3A,TK2,RPRM,VGF,REEP1,EVI5" Drug 6389_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADD2,ADORA2A,LTBP4,BEGAIN,TRMT9B,GAS7,BCAS1,ARNTL,ARRB1,ATP6V0A1,KIF1A,BMP7,SCAPER,CACNA2D1,HAP1,RUNX1T1,FOXN3,NRXN3,PLAA,CRMP1,ABCG1,CSF1,DMPK,EGFR,PRELID3A,ALDH1L1,SRCAP,ADAM28,TDRKH,PGAM2,VPS13C,WDR25,PTPRD,CSRNP3,ASAP3,SLA,PREX2,PKNOX2,TSNAXIP1,ZHX3,SPTAN1,IQSEC2,DDN,NR2E1,PIK3R5,TPM1,RPRM,KCNAB1" Drug 7259_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "TRMT9B,AMH,PPFIA3,RAB29,MYRF,KRIT1,CBFA2T2,NCOR2,ARHGEF10,CNTNAP2,SLITRK5,BRINP1,RUSC2,LYPD1,ING4,ANKMY1,ERGIC3,SIGLEC8,POLL,GNAL,SPACA9,MAN1B1,SCIN,INPP5B,KIF2A,MITF,NOVA1,ZCWPW1,RGS4,RGS12,SCN8A,SH3BP2,SMARCD3,MYH15,ZSWIM8,SPP1,ZBTB43,SS18,CEP68,ZEB1,TK2,BEX4,R3HDM1,TRIO,EMSY,EPM2A,KAT6A,PHTF2" Drug 5083_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "PPFIA4,ADGRB2,NRP2,BAIAP3,CA8,CACNA1A,THSD7A,RUNX1T1,SLC16A4,ENTPD2,CNTFR,SHANK1,HEYL,MTSS1L,HPCAL4,AGAP2,AFF2,EFCAB2,ZNF44,NEU3,RUNDC3A,MSL3,POLL,GNG4,GRM2,SOX21,KCNF1,LSS,AFDN,MMP16,ADAM22,MSR1,NELL2,NF1,OPRL1,PID1,RGS12,FRMPD1,SLC6A11,KDM4B,SOX15,HECW1,ZNF423,SPTB,PHLDB1,CHST8,XRCC4,FAM13C" Drug 7192_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ASIC1,AP2A2,CDC42BPA,APOC1,CDC14B,ARNTL,SLC4A4,CFLAR,SYNJ2,SCAPER,CAMK2B,ARHGEF2,LHX2,FAM189A2,NCOR2,LRIG1,MFAP3L,PARD6A,SNX29,COQ7,DENND4A,DLC1,KAT8,OLFM1,BAIAP2,FHL1,TRMO,NEU3,GCNT2,ITPKB,LIG4,MGAT3,LYRM9,NFYA,RETREG1,STRN3,PRPH,ZFP30,SH3GL3,SYBU,SLA,PPP4R3A,SPART,ELOVL4,TK2,ZNF45,SEMA3B,PHTF2" Drug 2350_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "C3orf14,NDRG3,PLA2G4C,MARK4,BACH1,BMP7,CACNA1A,CD86,CDH2,CPS1,VCAN,SLITRK5,DZIP3,ARHGAP32,DGKG,DBT,CNNM1,PLXNC1,MRNIP,VPS13B,RASGRP2,NCALD,ZNF589,PRKAG2,PDLIM5,ERAP1,DISC1,INPP5K,LILRA2,GRB10,GRIK5,HNMT,KCNN1,GIT1,NF1,NPR2,BCAS3,PTCH1,PTPN13,TMEM231,MRAS,SH3BGR,SH3BP2,DZIP1,SNCA,ATP10B,SSBP2,KCNAB1" Drug 5528_UP Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "AMT,CDC42BPA,APBA2,APC,CDC14B,SEMA4G,PDE8B,ALDH7A1,CACNA1I,CFAP410,CACNA1A,SEPT7,CNTFR,WHRN,CSF1R,VCAN,DGKG,GABRG2,TMEM8B,GPR162,RUNDC3A,POLL,GRIK5,KCNJ5,KCNN1,LAMA2,MAN2A2,NOVA1,NTRK3,GPR85,PPP2R2B,MAPK10,SNRK,ELOVL2,TCP11L1,CNKSR2,PKNOX2,KIF13A,ATP10B,ST5,CEP68,TACR1,MCF2L,CUX2,SZT2,CRTC1,SLC35G2,TK2" Drug 2654_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ASIC1,APBB2,PPP4R4,MARK4,SLC2A11,BAIAP3,CACNA1A,CNTFR,AKAP7,NRG2,CSF1,IPCEF1,PDE4DIP,MFAP3L,RUSC2,C2CD2L,MBNL2,HSD17B14,VPS13B,RASGRP2,SPEG,PIPOX,FAM198B,FGFR1,SEMA4D,FLNC,NSG1,SIGLEC8,GNAO1,GSTM5,RASSF8,ATXN2L,INPP5B,LSS,ZNF862,NLE1,PPP5C,SNRK,ZC3H13,SPTAN1,IQSEC2,ARC,THRA,HEY1,TK2,SPHK2,GDPD5,TIGD6" Drug 5804_UP Lidoflazine [3416-26-0]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ASIC1,LTBP4,ALK,BACH1,SYNGR3,MAGI1,FOXN3,CHRNA4,WHRN,AKAP5,ABCG1,FAM131B,SPOCK3,DMPK,EDIL3,RASGRP2,PIPOX,F5,CORO2B,ST3GAL6,HPCAL4,AFF2,ERAP1,SIGLEC8,SRCAP,RUNDC3A,SPACA9,GRIK5,GRM8,ADAMTS6,KHK,KIT,AFF1,TAGLN3,NPTX1,GPR85,PID1,ACSS3,FRMPD1,ARHGEF40,SNCA,SSTR2,DIP2A,COBL,PCDHA5,CHST5,FLRT2,REEP1" Drug 6152_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "BRAP,C1QTNF1,SYT13,CDC42BPA,APOC1,CDC14B,PLA2G4C,BMP7,SYNJ2,MTMR3,GYG2,EXOG,RCAN1,DTNA,FAM13A,ING4,EIF1,EPB41,STX2,FER,AGAP2,EFCAB2,PDLIM5,KHDRBS3,GCNT2,GLYR1,GPD1,PCLO,MMP16,MYO6,NTRK2,OCRL,CLDN11,GDPD2,RGS4,CARF,RPS20,FERMT1,FUZ,TMCC1,KDM4B,ARHGAP26,SPTAN1,DDN,DMXL2,TLR4,HIRA,ACTR3B" Drug 7464_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ASIC1,AMPD3,KCNAB2,APC,SEMA4G,ATP1A3,MTMR3,GYG2,CBFA2T2,MAGI1,RCBTB2,ARMC8,ARHGEF10,VCAN,TBC1D5,DAPK3,JAKMIP2,MFAP3L,TMCC2,EDN1,CELSR3,MRNIP,ELN,BAIAP2,AGAP2,ERAP1,SYT17,RAB30,RNFT2,ACOT7,ITGA7,KCNB1,SMAD1,MAP4,MAPT,MPP2,NPTX1,SLC25A23,PRKAR1B,PRPH,WDR25,PTN,RIPOR1,SNCA,ASTN2,EXOC7,PARD3,TFIP11" Drug 5761_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADD2,NRP2,CALB2,CAMK2B,RUNX1T1,CDO1,LHX2,VAX2,HOMER3,WHRN,CRMP1,SEC14L5,PLXNC1,RGS17,MTSS1L,NRN1,HPCAL4,NSG1,INPP5K,GNAL,ELOVL5,ICA1,SHISAL1,C2orf72,LAMA2,LMO2,MBD1,MSR1,TAGLN3,NPTX1,PDE4D,RETREG1,SEPT4,PRKCB,MASP1,FAT4,CCDC102B,NEK11,FRMPD1,PPP4R3A,DMXL2,SLC44A1,ICAM5,TRO,FLRT2,VLDLR,LAT2,SLC17A7" Drug 2188_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADORA1,TRMT9B,BIN1,CDC42BPA,DDO,PPFIA3,CDK13,LDLRAD4,TAOK2,STOML1,AKAP6,ABI3BP,PDE4DIP,HEYL,FAM13A,HSD17B14,EPHB1,ERBB2,FLT1,DLL3,ADAM28,GFER,SPACA9,KIF5A,MARK1,NNAT,NTRK2,OPRL1,PFKFB4,PLEC,PMP22,PPP2R2B,RELN,RNASE1,STUM,RASA3,FERMT1,EPN2,PKNOX2,SLC6A8,TMCC1,ZC3H13,SPTB,LMF1,CLIP2,XRCC4,PLSCR4,JPH3" Drug 7289_UP Phenindione [83-12-5]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "AGT,ADGRF5,KCNAB2,APOC1,CDK10,ALDH7A1,SYNJ2,MYRF,TAOK2,NRXN3,HOMER3,AKAP5,ARHGEF10,CHRDL1,HIPK3,EPB41,COQ7,MTSS1L,ZNF44,GAD1,GNAO1,SPACA9,DHX35,TJAP1,KHK,MATN3,ZNF862,PALM,PFKFB2,PFKFB4,FA2H,CNNM2,ELOVL2,RTN1,SUPT20H,AMBRA1,PPP4R3A,SIRT2,ZHX3,SPP1,UNC5B,SPTB,THSD1,SS18,THRA,LAT2,KCNAB1,DPF3" Drug 2783_DN Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "NDRG3,DOC2A,APC,ARNTL,CFLAR,SYNJ1,CA12,HOMER3,PDE4DIP,MAML1,JAKMIP2,DTNA,CNNM1,VPS13B,NCALD,KAT8,FGFR1,SEMA4D,DISC1,ALDH1L1,MALT1,GLYR1,GNG4,RASSF8,AGBL5,KITLG,MMP16,NEK1,CNOT4,PLCD1,LRP12,ZSCAN32,C1orf54,RGS12,RNASEL,MCMBP,ANKRD6,SLC6A8,SMARCD3,RBM34,TROVE2,STX1A,KAT6B,CDK20,RUNDC3B,VGF,PHTF2,SENP7" Drug 3255_UP Metrizamide [31112-62-6]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "NDRG2,NME5,ZBTB10,ATP2A2,ALDH7A1,ATP6V0A1,ADAM15,GYG2,CLGN,ENTPD4,RIMS2,SPOCK2,C2CD2L,DTNA,DUSP9,FCF1,FRY,MRNIP,SPEG,FGFR1,GLYR1,GPER1,GSTM5,KCNH2,LMO2,KITLG,ZNF862,NFYA,PFKFB2,SLC25A23,STRN3,CNNM2,ELOVL2,RAD51D,C1orf54,KCTD17,KLHDC8A,FBXO11,SLC11A1,CDK19,TSPYL2,NXT2,PHLDB1,SYNE1,TK2,TMPO,WIPF1,LAT2" Drug 4066_UP Xylazine [7361-61-7]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "LTBP4,PPFIA4,PRX,ARHGDIG,BCHE,KALRN,RUNX1T1,CD86,TAOK2,TPP1,CSF1R,RGS6,LRIG1,ING4,NCALD,PIPOX,KAT8,AGAP2,PDLIM5,OGA,DISC1,GPR162,STMN2,SPACA9,CACFD1,GSTM5,SCIN,KCNF1,AFDN,TAGLN3,NF1,NTRK2,PLCD1,DCHS2,RFX2,KLHL11,ZNF821,RASA3,ZNF334,TACR1,KLHL4,PHF24,HIF3A,TNS1,RPRM,VIPR2,UBE3B,DPF3" Drug 3399_DN Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "AK2,LTBP4,APBA2,FAM131A,PPP4R4,PLA2G4C,CDK13,PDE8B,NRP2,GYG2,LDLRAD4,SLC16A4,SEPT7,LHX2,STOML1,CRY2,CSF1,CSNK1E,KIAA0586,CDON,SCARA3,AGAP2,SRCAP,IL6R,KHK,MAP4,MSI1,ADAM22,PALM,PDE1C,ZDHHC14,ZFHX4,EMID1,ASAP3,FNDC3A,LIMCH1,SOX3,TROVE2,EXOC7,TBCEL,SMG6,DMXL2,OBSL1,CRTC1,TK2,FAM155A,SPHK2,MAP3K12" Drug 610_UP monastrol; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADCY6,LTBP4,APOC1,PPFIA3,ARNTL,EIF4G3,SGCE,CAMK2B,MAGI1,CHN1,TAOK2,CREM,CRMP1,DZIP3,KIAA0586,RCAN1,TOM1,TNK2,VPS26C,EXTL2,DLC1,OLFM1,SCARA3,FAM49B,NSG1,KIF5A,MAP4,MAPT,MMP16,ADAM22,MYT1,NF1,NPTX1,NTRK3,PPM1B,MASP1,PTPRD,PTPRN2,GALNT10,ST6GAL1,LIMS2,TSPYL2,SPART,NSFL1C,OBSL1,TRPM2,PDIA2,WNT7A" Drug 2991_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "NDRG2,SEMA6A,ATP1A3,CDH2,DLGAP1,AKAP6,PHF14,MFAP3L,KLHL3,PARD6A,EDNRB,VPS13B,ZNF549,APC2,OLFM1,FGF12,FHL1,CAMKK2,NSG1,FYB1,GCK,SRCAP,SPACA9,PRDM5,RASSF8,LIG4,PACRG,MN1,NPTX1,TREM2,PDE4A,PRKAR1B,BCAS3,CCDC40,BEND5,NEK11,KIF16B,PEX26,ZC3H13,ATP10B,SYT1,TACR1,CRTC1,AP4E1,TRPS1,SSBP2,RPRM,XRCC4" Drug 4806_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "SEMA6A,CDC14B,CAMK2G,CBFA2T2,ARHGEF2,PLEKHB1,TAOK2,RAB28,FAM149A,NECTIN3,CNTNAP2,RIMS2,DAPK3,ERBB2,DENND4A,CORO2B,AGAP2,GALC,HPGDS,POLL,KCNH2,KCNN2,KIF5A,LIG4,MID1,ZNF862,NFYA,SLC25A23,PPP5C,MAPK7,PRPH,TCP11L1,FRMPD1,ASAP3,CPEB3,FNDC3A,FAM214B,SS18,SYT5,EXOC7,TBCEL,R3HDM1,TRIO,FAM155A,WIPF1,CLDND1,ST7,AP3B2" Drug 4238_UP Seneciphylline [480-81-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "NME5,PKP4,KCNAB2,PPP4R4,ATP6V0A1,HAP1,CAPN3,CBS,SEPT7,ASIC3,COL9A3,NRG2,CNTNAP2,RIMS2,MFAP3L,CHRDL1,ECM2,EDNRA,SEMA3D,PTK2B,FLT1,PCDH17,CSDC2,GPER1,NXPH3,IL6ST,FAM69A,KHK,TAGLN3,NPR2,NPTX1,NTRK3,CNNM2,PTCH1,GAL3ST4,RGS4,TCP11L1,KCNIP1,RTN1,OGDHL,SNAP25,ZHX3,SPTB,NFASC,LAT2,ZNF225,NT5M,KCNAB1" Drug 5450_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "AMPD3,APBA2,KCNAB2,GAS7,SEMA4G,RGS20,RASL11B,ATP6V0A1,LDLRAD4,LY86,CRMP1,CSF1,JAKMIP2,DMD,SLC12A6,ECM2,ING4,STX2,ERCC2,ZNF589,AGAP2,KHDRBS3,GFER,GNAL,GRB10,ICA1,INSM1,MAN2A2,MAP4,MAPT,MEF2C,MYO7A,NDP,CLDN11,PDE1C,PTN,RGS12,RPS6KA2,SEMA6D,ZNF821,HKDC1,FAM214B,IQSEC2,SZT2,DICER1,XRCC4,SLC17A7,KCNAB1" Drug 5775_UP Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADORA1,ADRA1D,BEGAIN,TRMT9B,APAF1,BCAS1,LGR5,ADAM23,BMP7,MYRF,CD86,CHN2,B4GALT6,DPP6,DTNA,EDN3,ING4,TNK2,COQ7,FGF1,SEMA4D,OGA,SYT17,NEU3,SRCAP,STON1,MCHR1,SPACA9,SOX21,NXPH3,SHISAL1,KCNH2,ADAM22,NRCAM,PNMA3,PPP2R2B,CEP41,MAPK3,PRODH,PID1,ENOX1,KCTD17,RNASE1,OGDHL,DOK5,CUX2,PRDM10,HRASLS" Drug 4017_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-07 9.26E-03 1.82E-05 2.05E-04 48 197 "ADD2,AP2A2,BBOX1,ARHGDIG,CDK13,CBFA2T2,TPP1,CNTFR,ENTPD4,HAPLN1,SPOCK2,DTNA,HIPK3,FRY,ETV1,PTK2B,FGFR1,NSG1,SIGLEC8,PCDH17,CACFD1,IL12A,INPP5B,MATN3,NPTX1,ENPP2,PLCD1,PPP2R2B,PTPRB,PTPRN2,C1orf54,BEND5,RFX2,RGS12,KLHL11,GSTCD,NEK11,SPTAN1,SPTB,SYT5,MCF2L,SLC44A1,CHST5,ZNF24,KCNAB1,PARP11,PHTF2,DPF3" Drug 6609_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.18E-07 9.57E-03 1.87E-05 2.11E-04 44 174 "ADRB2,SYT13,AMH,APAF1,EPB41L5,ARNTL,ATP1A3,ST3GAL5,NRXN3,ENTPD4,ABCG1,VCAN,PDE4DIP,CNTNAP2,CTH,PLPPR4,CHRDL1,TAOK3,DLC1,BAIAP2,FYN,GSN,FAM69A,LIFR,KITLG,SERPINI1,RETREG1,PRPH,PID1,ENOX1,RGS4,FBXW7,SH3GL3,ASAP3,DOP1A,DOK5,THSD1,ELOVL4,RGL1,SYT1,COBL,RUNDC3B,KCNAB1,DPF3" Drug 2247_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.28E-07 9.99E-03 1.95E-05 2.19E-04 45 180 "ABHD6,NME5,MARK4,ST3GAL5,BAIAP3,CLGN,WHRN,PDE4DIP,DOCK4,ARMCX2,TSPAN5,FAM13A,RASGRP2,HPCAL4,FYN,CYP46A1,RAB40B,STON1,RNFT2,SYNPO,PCDH9,TMOD2,SERPINI1,PLCD1,GRAMD1C,PRPH,PTCH1,SATB1,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,TRPM2,SSBP2,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 2639_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.28E-07 9.99E-03 1.95E-05 2.19E-04 45 180 "ABHD6,ALCAM,MARK4,ST3GAL5,CLGN,PDE4DIP,ARMCX2,JAKMIP2,TMCC2,TSPAN5,FRY,MBNL2,FYN,ALDH1L1,CYP46A1,STON1,GPR37,KCNN2,MITF,MXI1,PCDH9,SERPINI1,RETREG1,PLXNB1,PKIA,PRPH,RPS6KA2,SH3GL3,PPM1E,WDR47,FAM214B,SPTAN1,ELOVL4,CEP68,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SSBP2,REEP1,SLC30A3,SLC17A7,ITM2C,SMIM8" Drug 3236_UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-07 1.07E-02 1.99E-05 2.24E-04 47 192 "NDRG2,SPARCL1,CDK13,ATP1A3,NRP2,CA4,CLGN,ARHGEF10,VCAN,ARHGEF4,MFAP3L,EDNRA,EGFR,AASS,TNK2,ARMCX1,FGFR1,IQCG,ALDH1L1,GLYR1,ADAMTS13,HMGCR,LSS,SMAD1,MAN2A2,MATN3,MMP16,GIT1,ADAM22,TAGLN3,ZNF862,NNAT,PCBP3,LRP12,CCDC102B,RPS6KA2,SBF1,CPEB3,ARHGAP26,SPTB,TRIM2,TPM2,CHST5,FAM155A,FLRT2,NT5M,SENP7" Drug 4429_UP "ICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.43E-07 1.07E-02 1.99E-05 2.24E-04 47 192 "NDRG2,FAM135A,ANK2,LGR5,CDC14B,KSR1,BMP7,LDLRAD4,KALRN,MAGI1,RAB33A,TPP1,CABP1,LRIG1,SPOCK2,EDN3,SEMA3D,EPHB1,CORO2B,ST3GAL6,FGF1,OLFM1,SEPT9,SRCAP,CACFD1,GRM8,SOX21,PADI2,TJAP1,LMO2,NPTX2,ENPP2,GPR85,ACSS3,TCP11L1,KCNIP1,SALL1,ZFP2,PKNOX2,SLC11A1,ZNF334,HECW1,ATP10B,PHLDB1,PCDHGB6,OBSL1,RIMBP2" Drug 3905_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-07 1.07E-02 1.99E-05 2.24E-04 47 192 "ASIC1,ABHD6,ALCAM,MARK4,CFAP410,CAMK2B,RCBTB2,RAB33A,CNTN1,WHRN,ABCG1,PDE4DIP,KIAA0586,CELSR3,ANKMY1,ST3GAL6,OLFM1,AGAP2,ALDH1L1,GFER,GLYR1,POLL,ADAMTS13,ITGA7,MAPT,ZNF862,SERPINI1,SMIM7,CEP41,GRAMD1C,TMEM231,ENOX1,RPS6KA2,RPS20,KCNIP1,CLIP1,ZFP2,CPEB3,EPN2,ATP10B,DICER1,CHST8,TRPM2,LMF1,WIPF1,XRCC4,HPS4" Drug 3509_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADORA1,AMPD3,CDC42BPA,SEMA7A,APBB2,FAM131A,SEMA4G,CFLAR,KSR1,MYRF,CA4,ARHGEF2,SEPT7,LARGE1,CDO1,ARHGEF6,PDE4DIP,CNTNAP2,SNPH,SPOCK2,TMCC2,DTNA,EDNRA,COQ7,LRRC17,FGFR1,ZNF44,LYVE1,GLYR1,LPAR4,SOX21,MITF,MSR1,MYO7A,NF1,PFKFB2,PPARA,MINDY2,C1orf54,PKNOX2,SLC12A4,DOK5,CRTC1,CHST5,UCHL1,FLRT2,KCNAB1,ADAMTSL3" Drug 5770_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADD2,SEMA6A,BEGAIN,TRMT9B,EPB41L5,APOC1,RGS11,CFLAR,BMP7,CACNA1I,MYRF,MAGI1,TAOK2,ARHGAP22,PICK1,AKAP5,SPOCK2,EDN1,CELSR3,MBNL2,ING4,FGF1,HPCAL4,OGA,ZNF44,LILRA2,LPAR4,IL12A,KCND1,LMO2,MATK,ADAM22,TAGLN3,MYT1,PCBP3,MAPK10,VPS13C,RET,ZNF821,OGDHL,HECW1,SSTR2,PCDHA6,AP4E1,TLR4,TNS1,SLC17A7,KCNAB1" Drug 4689_UP Riluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "RALGAPA1,AMPD3,KCNAB2,FAM131A,PPP4R4,PLA2G4C,NRP2,CFLAR,BAIAP3,FAM149A,ENTPD4,FAM169A,CTH,GIT2,FGFR1,GALC,GRB10,GRIK5,CACFD1,GRM8,C2orf72,JAK2,MID1,MN1,MYO7A,NFYA,NPR2,PALM,PFKFB2,SERPINI1,STRN3,LRP12,LRRN3,RGS12,GSTCD,CCDC25,FRMPD1,SMARCD3,SNCA,ZC3H13,ZBTB43,TROVE2,ST5,PCDHA6,PCDHA5,AMACR,ZFP37,NLRP3" Drug 5627_DN Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADRA1D,CDC42BPA,FAM131A,PDE8B,MTMR3,GYG2,ARHGAP33,FOXN3,TPP1,STOML1,SULT4A1,DZIP3,GIT2,ARMCX2,JAKMIP2,LYPD1,RRAGB,ZNF589,FER,BAIAP2,TRAF3IP2,DISC1,ALDH1L1,RAB30,ELOVL5,INPP1,KHK,IPO5,LMO2,TM6SF1,CNOT4,NPTX1,LRP12,PRKAR1B,TMEM104,ELOVL2,PLCB1,DMXL2,TMEM121,TK2,PARD3,CABIN1,TPM1,TRIO,RUNDC3B,FAM155A,REEP1,GDPD5" Drug 3879_UP Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "RALGAPA1,AGT,ALCAM,TRMT9B,APC,GAS7,ADAM23,ARHGEF6,CNR1,NCOR2,DNAH9,DYNC1I1,FAM13A,OLFM1,FGFR1,CAMKK2,GFER,PRUNE2,GPER1,IRF8,KCNB1,KCNN2,L1CAM,SMAD1,MMP16,ADAM22,ZNF862,NF1,OPRL1,RETREG1,NECAB2,CEP41,RPS6KA2,EMID1,ZNF821,SH3BP2,ASAP3,FAIM2,TROVE2,SAMSN1,TBL1X,CRTC1,TRIO,HIRA,SLC30A3,EMSY,SLC17A7,DPF3" Drug 6759_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADCY6,LTBP4,APBB2,LGR5,PPP4R4,RGS11,MYRF,CFAP410,CA4,HAP1,SLC16A4,ARHGAP33,AKAP6,FAM131B,DGKB,DTNA,DTNB,ING4,MRNIP,REEP2,FGF12,AFF2,CHL1,ALDH1L1,SRCAP,PRUNE2,SPACA9,ITGA7,PACRG,P2RX7,PDE4A,DCHS2,PTPRH,TMEM231,ZNF821,SLA,PREX2,ZSWIM8,IQSEC2,CEP68,EXOC7,DICER1,TK2,TNS1,RUNDC3B,TRO,DPF3,JPH3" Drug 5457_UP Naproxen [22204-53-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "AGT,APAF1,APC,APOC1,KSR1,SYNJ2,MTMR3,SGCE,CDH2,CLGN,TPP1,CREM,GREB1,MFAP3L,ING4,RGS17,ELN,RRAGB,FAM198B,DLC1,FGF13,FGFR1,ERAP1,SIGLEC8,ADAMTS13,NXPH3,ICA1,MAN2A2,MAP4,CLDN11,PDE1C,MAPK10,RGS4,TCP11L1,SH3BP2,CPEB3,FAM214B,CDK19,ARC,TACC1,DOCK9,CRTC1,CHST8,CDK20,HIRA,PDIA2,XRCC4,SLC30A3" Drug 4343_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASPHD1,FAM135A,APAF1,CDC14B,CDK10,PPP4R4,RASL11B,N4BP2L1,BCL7A,CACNA1I,CFAP410,STOML1,AKAP6,CYBB,MAML1,EDN1,LRRC17,FLT1,DENND2A,ERAP1,SOX21,PADI2,AGFG1,ICA1,TM6SF1,MMP16,NELL2,NOVA2,NPR2,NTRK2,PIK3R1,STRN3,CCDC40,RGS4,KIRREL1,SH3BP2,CPEB3,ZNF334,ZNF667,SP4,HECW1,IQSEC2,RBM26,THRA,TUBB1,NT5M,KCNAB1,KAT6A" Drug 3436_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "NDRG2,SEMA6A,LTBP4,DOC2A,AMPD3,BIN1,APC,APOC1,PPFIA3,MADD,CDK13,KIF1A,CFLAR,GYG2,LDLRAD4,TAOK2,HOMER3,PICK1,CSF1,GREB1,DCAF8,LYPD1,RCAN1,CNNM1,STX2,VPS26C,SRCAP,GLYR1,TDRKH,ADAMTS13,INPP5B,IPO5,LSS,KITLG,PLEC,PRKAR1B,PTPRE,GSTCD,TCP11L1,ANKRD6,PHLDB1,PLCB1,ZNF34,TK2,CDK20,SPHK2,ITM2C,PHTF2" Drug 6073_DN 6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASPHD1,AP2A2,AK2,C1QTNF3,PPFIA3,MARK4,ATP6V0A1,MTMR3,GYG2,CA12,HOMER3,PDE4DIP,ARHGEF4,RIMS2,MFAP3L,TMCC2,SUGP2,ING4,C3orf18,FAM198B,FGFR1,GNG4,FERMT2,KPNA5,MIA2,MPP2,MSI1,ADAM22,NPR2,PCDH9,PDE4B,PRKAR1B,PRPH,ELOVL2,NKAIN1,RGS3,MAPKBP1,ZHX3,THSD1,PHLDB1,SYN2,SLC44A1,TK2,PARD3,UBE2H,MAP3K12,EPM2A,PHTF2" Drug 3576_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASIC1,ALCAM,APBA2,APC,PPFIA3,PRX,PPP4R4,PDE8B,MARK4,LDLRAD4,SULT4A1,AKAP7,CRY2,KIAA0586,JAKMIP2,MFAP3L,FBXL5,EDNRA,PHF20L1,SUGP2,CDKL3,MALT1,TDRKH,RNFT2,ATXN2L,ICA1,KPNA5,MAPT,MBD1,KITLG,SCAMP5,NF1,NPTX1,MAPK7,CNNM2,NEK11,ZNF423,SAMSN1,STX1A,IQCE,ZEB1,CRTC1,THRA,TK2,LMF1,XRCC4,REEP1,EVI5" Drug 5326_UP Ioversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ABHD6,ADRA1D,SEMA6A,EPB41L5,GAS7,PPP4R4,MARK4,CFLAR,ST3GAL5,CFAP410,CAMK2G,NRG2,PDE4DIP,CTH,ARHGEF4,GIT2,EZH1,OLFM1,FGF12,PDLIM5,GFER,CLASRP,IPO5,MAP4,MEF2C,MPP2,MSI1,NFYA,NPTX1,PFKFB2,NLE1,CNNM2,SAMD9,NEK11,EMID1,CLIP1,SYBU,PREX2,PEX26,ARHGAP26,IQSEC2,WSCD1,HIRA,FAM155A,NDRG4,GDPD5,KCNAB1,AP3B2" Drug 6698_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADD2,ADGRF5,PPFIA4,APBB2,APC,BCAS1,ADAM23,BMPR1B,GYG2,CACNA1I,RAB28,CLTB,PCYT1B,SLC4A8,HAPLN1,CRY2,CNTNAP2,PHF14,DAPK3,RUSC2,EDIL3,EDN1,EPB41,RASGRP2,ETV1,ST3GAL6,ZNF589,EFCAB2,GLYR1,GPR75,STMN2,GRM8,SOX21,ITGA7,ADAM22,NELL2,PFKFB2,PPP1R1A,LRRN3,TCP11L1,SH3BP2,DZIP1,PKNOX2,ZSWIM8,SPTB,ARHGEF9,PCDHA5,TIMP4" Drug 4374_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADORA1,LTBP4,CDC14B,ATP2B2,CAMK2B,RAB33A,SULT4A1,ARHGEF4,SNPH,INTS1,DNAH9,HSD17B14,F5,REEP2,DLL3,GABRG2,SIGLEC8,GFER,RUNDC3A,GLI2,GNG4,GRM2,GRM8,IFI16,KCNH2,AFDN,MN1,TAGLN3,MYCN,MYT1,NNAT,RFX2,CARF,EMID1,CNKSR2,DZIP1,IZUMO4,HECW1,CDK19,TACR1,TCF4,ICAM5,R3HDM1,UGT8,LAMP5,DNALI1,PLSCR4,TIGD6" Drug 6175_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADRA1D,APC,CDC14B,SLC4A4,ALDH7A1,CACNA1I,CA4,TAOK2,CNN3,CNR1,CSNK1E,SIPA1L1,PARD6A,SV2B,TMCC2,CDON,MRNIP,HSD17B14,OLFM1,SIGLEC8,GPR162,CSDC2,ZNF276,GPD1,MSR1,NPR2,OXTR,GRAMD1C,CNNM2,GDPD2,PTPRN2,RASGRF1,GAL3ST4,MORC4,RGS12,KCNIP1,SEMA6D,SH3BGR,ASAP3,ZC3H13,NFASC,SLC35G2,ICAM5,TUBB1,LMF1,VSNL1,KCNK12,KCNAB1" Drug 6009_DN Lansoprazole [103577-45-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "TRMT9B,AMT,FAM131A,ARRB1,PDE8B,SLC2A11,ALDH7A1,ADAM23,SYNJ2,CACNA1I,CRLF1,B4GALT6,CSF1R,PHF20L1,SUGP2,MBNL2,FAM198B,KAT8,ZNF589,FHL1,TRAF3IP2,TXNL4A,MSL3,GNG4,TDRKH,CNTRL,GRM8,KHK,TM6SF1,TAGLN3,LRP12,PRPH,RET,ANKRD6,PREX2,KDM4B,SPTAN1,SPART,TROVE2,EXOC7,IQCE,CRTC1,TK2,RIMBP2,VGF,VIPR2,XRCC4,ZFP37" Drug 5805_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASIC1,ADRA1D,TRMT9B,APC,KSR1,BTK,CACNA2D2,ARHGAP22,RAB33A,CNTN1,ARMC8,WHRN,CRMP1,NCOR2,ARHGEF10,ARMCX2,CORO2B,FGFR1,SYT17,DISC1,ALDH1L1,SPACA9,SOX21,KCNB1,KIFC3,TAGLN3,NKAIN1,PID1,ACSS3,RFX2,SEMA6D,STUM,DZIP1,SLA,PKNOX2,BTBD7,OGDHL,PDZRN3,KDM4B,ATP10B,COBL,TACR1,TLR4,WIPF1,REEP1,TFIP11,MAP3K12,KCNAB1" Drug 5507_UP Sulfaphenazole [526-08-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ABHD6,BIN1,CDK10,ARRB2,PLA2G4C,ALDH7A1,RIPK1,CFLAR,CACNA1G,CFAP410,CAMK2B,SLC16A4,CLGN,FOXN3,QKI,CSF1R,LRIG1,RIMS2,DPP6,DTNA,VPS13B,NRN1,FGF13,GNAO1,HNMT,KHK,LIG4,MMP17,NFYA,NTRK3,PLCD1,SLC25A23,STRN3,LRP12,RELN,ELOVL2,PTPRE,ZMAT4,ZFHX4,SYBU,ANKRD6,IZUMO4,THSD1,CEP68,STX1A,PLCB1,WSCD1,KIAA0930" Drug 7489_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "NDRG2,ADORA2A,C1QTNF3,SEMA6A,APBB2,APOC1,CDK13,ADGRB1,BMP7,SYNJ2,CHN2,VAX2,CNTN1,WHRN,BAG4,NRG2,PDE4DIP,TMCC2,TOM1,EGFR,MBNL2,STX2,FLNC,RASSF8,HNMT,TJAP1,IL6ST,ITPKB,KCNH2,KIT,NF1,CNOT4,PLCD1,SLC25A23,LRRN3,MAPK7,SOX15,KDM4C,STX1A,ASTN2,WSCD1,PCDHA5,SLC44A1,TRIO,TUBB1,UCHL1,FLRT2,KCNAB1" Drug 7437_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "AK2,APBB2,PPFIA3,ARHGDIG,MARCH3,ADAM15,MPDZ,BMP7,SCAPER,SGCE,CFAP410,CA12,NECTIN3,ENTPD4,RIMS2,DCAF4,GIT2,PARD6A,TOM1,HIPK3,MBNL2,IRAK4,COQ7,VPS26C,ZNF589,FHL1,PRELID3A,ERAP1,ALDH1L1,MALT1,IL6ST,KCNF1,KITLG,NF1,SETD4,SLC25A23,PPARA,PRPH,RIPOR1,NEK11,EMID1,ARHGAP26,ANKRD12,WSCD1,LMF1,ZBTB14,MAP3K12,PHTF2" Drug 2228_DN Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASIC1,LTBP4,PLA2G4C,MARK4,ATP6V0A1,CFLAR,SYNJ2,CACNA1A,ARHGAP33,PICK1,CSF1,CSF1R,SEC14L5,DCAF8,DAPK3,CDON,STX2,ZNF589,FGFR1,FHL1,EFCAB2,PDLIM5,FAM49B,CNTRL,GRIK5,GSN,GSTM5,TJAP1,INPP1,JAK2,ADAM22,SLC11A2,MAPK7,EMID1,FAM192A,SYBU,SLC6A8,BTBD7,ARHGAP26,THSD1,PLCB1,RPGRIP1L,TNS2,CABIN1,RUNDC3B,SPHK2,SMIM8,GAN" Drug 7380_UP Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "CDC42BPA,KCNAB2,EPB41L5,SHROOM2,PDE8B,ATP1A3,ATP6V0A1,CACNA2D2,NCOR2,ARHGEF10,KIAA0753,DPH1,DRP2,EDN1,IRAK4,COQ7,FER,FGF13,ERAP1,ALDH1L1,SPACA9,HNMT,HSF2,SHISAL1,KCNN1,ADAM11,MGAT3,NF1,CLDN11,PLCD1,PPP5C,GDPD2,WDR25,PTCH1,FBXW7,TRAPPC13,ASAP3,ARHGEF40,POGZ,ST5,PHLDB1,VPS13A,SYT1,ASTN2,DOCK9,KCNAB1,UBE3B,NLRP3" Drug 5257_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "KSR1,CACNA1G,CFAP410,RUNX1T1,CDO1,SULT4A1,ABI3BP,NCOR2,SNCAIP,INTS1,DBT,SPOCK3,MRNIP,APC2,KHDRBS3,FUT9,SIGLEC8,DISC1,GCNT2,ADAM28,GFER,RUNDC3A,GNAO1,GPER1,ADAMTS13,ATXN2L,HLF,LSS,TAGLN3,MX1,PFKFB2,PLTP,PILRA,MINDY2,PRKCB,FAT4,ZMAT4,KLHL11,ZNF821,NLGN1,SLC11A1,ZNF423,SPTB,RBM26,WSCD1,SZT2,CRTC1,FLRT2" Drug 5639_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ADD2,LTBP4,ALK,SYT13,CDC42BPA,ARHGDIG,ADGRB1,BAIAP3,KALRN,HAP1,TAOK2,RAB33A,CNN3,PICK1,SNPH,SPOCK2,HS3ST2,EGFR,DISC1,NEU3,AHDC1,POLL,PRUNE2,GRIK4,HLF,KCNJ5,KCNN2,KIF5A,MEF2C,MID1,ZNF862,NOVA2,NPR2,PFKFB2,PLCD1,PLTP,PURG,CNKSR2,FAM214B,PKNOX2,SLC11A1,LIMCH1,CLSTN2,RGL1,SYT5,WSCD1,TRPM2,JPH3" Drug 4410_UP Captopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "ASIC1,ADORA1,BIN1,AZGP1,CFAP410,CACNA2D1,CAST,RUNX1T1,CDO1,QKI,CNR1,COL9A3,NRG2,NCOR2,DBT,MFAP3L,C2CD2L,TMCC2,VPS13B,SPEG,DLC1,ZNF589,GAD1,NEU3,GPER1,ADAMTS13,GSTM5,IRF8,NF1,CNOT4,NPTX2,PALM,C19orf57,TRIM68,ZFHX4,FBXW7,SEMA6D,ZFP2,LIMCH1,SPP1,CDK19,ATP10B,PLCB1,UGT8,XRCC4,ITM2C,PHTF2,DPF3" Drug 2714_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "CDC42BPA,GAS7,MYOM1,CFAP410,THSD7A,SCARB1,DLGAP2,CHN1,B4GALT6,TAOK2,SEC14L5,GPRASP1,DAPK1,SPOCK2,MAMLD1,HIPK3,RASGRP2,TBC1D16,OLFM1,BAIAP2,DCTN2,PRELID3A,SIGLEC8,PCDH17,RUNDC3A,CACFD1,MBP,MGAT3,SCAMP5,MYO6,NELL2,PDE1C,TMOD2,PRKAR1B,KLK6,PTPRN2,SUSD4,RGS4,LIMS2,SLC12A4,DOK5,ZHX3,KLHL4,CUX2,PCDHA6,SLC35G2,SPHK2,SLC17A7" Drug 1499_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "NDRG2,C1QTNF1,BIN1,APBB2,APC,BCAS1,PPP4R4,SLC4A4,ADGRB2,GYG2,CAMK2G,ARHGAP33,CACNA2D2,TAOK2,RAB33A,GREB1,TMCC2,DTNA,MBNL2,EIF4G2,MRNIP,DLC1,KAT8,FGFR1,IQCG,PCDH17,GLYR1,TJAP1,TAGLN3,NACA,PIK3R1,CCSER2,MBOAT7,POLG,ZFHX4,EMID1,FBXO11,PPP4R3A,KIF13A,RBM34,HECW1,THSD1,ARC,ASTN2,SIN3B,UCHL1,LAT2,NT5M" Drug 2397_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "SRPX,CDC42BPA,APAF1,APC,ARRB2,MARK4,CFLAR,TPP1,AKAP7,CSF1,ZNF337,DAPK3,HEPH,EXOG,HS3ST2,DPH1,EDNRA,MBNL2,ING4,EIF1,TUBD1,SPEG,FGFR3,GLYR1,PRUNE2,ICA1,KCND2,MARK1,MEF2C,MYCN,NEK1,PDE4B,PLCD1,PLEC,SLC25A23,MINDY2,MASP1,SUSD4,RGS3,SH3BP2,SNCA,SP4,IQSEC2,TROVE2,SS18,STX1A,TRPS1,EMSY" Drug 4009_UP Sulmazole [73384-60-8]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "SYT13,AMH,PPFIA4,PKP4,BCAS1,CDK13,SLC4A4,BAIAP3,USP2,DLGAP2,NRXN3,AKAP5,CRY2,SUSD5,SPOCK2,SGSM2,TNK2,RGS17,FGFR1,HPCAL4,EFCAB2,OGA,LYVE1,GLYR1,PADI2,KCNJ5,KCNK3,KCNN1,LAMA2,ADAM11,TM6SF1,MTRF1L,PPP2R2B,LRRN3,GAL3ST4,PNMA8A,GSTCD,DZIP1,KANSL3,RBM26,COBL,SYT5,EXOC7,SLC44A1,LAT2,SLC30A3,KCNAB1,DPF3" Drug 4606_DN Metyrapone [54-36-4]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "MTUS1,MADD,ADAM15,CAMK2G,B4GALT6,CNOT8,QKI,WHRN,DBT,RUSC2,SGSM2,FEM1B,EIF5,TNK2,MRNIP,ZNF589,ANKFY1,FYN,DENND2A,TXNL4A,PRRC2B,MITF,NDP,PLCD1,PLEC,PPP5C,ZSCAN32,TCP11L1,SAFB,SBF1,ZFP30,AMBRA1,SMARCA4,SS18,EXOC7,IQCE,FBXW11,TCF4,KIAA0930,SZT2,ZNF34,AMACR,TRPM2,UBTF,XRCC4,TFIP11,EVI5,HPS4" Drug 6289_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-07 1.09E-02 1.99E-05 2.24E-04 48 198 "LTBP4,ALK,CDC42BPA,PPFIA3,PDE8B,ZSCAN18,N4BP2L1,NRP2,BTK,SCAPER,RAB26,HOMER3,ABCG1,SUSD5,TBC1D5,ETV1,RRAGB,EZH1,FYB1,TRAF3IP2,DENND2A,GAD1,LPAR4,IFI16,INPP5B,ITPKA,KCNJ5,KIFC3,KIT,MX1,NFYA,PDPK1,RGS12,PBRM1,DZIP1,PKNOX2,KIF13A,DOK5,SOX15,KDM4C,PBLD,TROVE2,TACR1,TIAM1,CDK20,LAT2,ZNF189,HRASLS" Drug 3428_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.60E-07 1.14E-02 2.08E-05 2.34E-04 44 175 "NME5,SRPX,ARNTL,BMP7,ST3GAL5,CLGN,UBE2L6,CRYM,PDE4DIP,ARMCX2,TSPAN5,OPTN,FYN,CYP46A1,RAB40B,STON1,RNFT2,MITF,MPP2,MXI1,NEK1,PCDH9,SERPINI1,PMP22,PKIA,PRPH,SH3GL3,PPM1E,WDR47,PKNOX2,SPTAN1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,REEP1,SLC17A7,ITM2C" Drug 4153_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.60E-07 1.14E-02 2.08E-05 2.34E-04 44 175 "ADRB2,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,CRYM,PDE4DIP,ARMCX2,TSPAN5,FAM13A,RASGRP2,HPCAL4,FYN,CYP46A1,STON1,KCNH2,MAP2,MEF2C,PDE4A,ABCB1,SERPINI1,PRPH,RADX,NUDT11,SH3GL3,ASAP3,ST6GAL1,WDR47,PKNOX2,CCDC88A,SOX15,NMNAT2,PEG10,ELOVL4,RGL1,STXBP1,HEY1,TNS1,RUNDC3B,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug 5224_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.79E-07 1.22E-02 2.21E-05 2.50E-04 46 187 "C1QTNF3,AMT,SEMA7A,APBB2,CDK13,MARK4,SCAPER,CBFA2T2,RCBTB2,CHRNA4,PDE4DIP,CTH,HS3ST2,SLC12A6,EDNRA,HEYL,MBNL2,ING4,INPP5K,ALDH1L1,GLYR1,STON1,HNMT,ICA1,LMO2,SMAD1,ZNF862,NEK1,PFKFB2,SERPINI1,ZCWPW1,ZNF493,CARF,PCMTD2,TCP11L1,SH3BGR,ZKSCAN3,TSNAXIP1,CDK19,THSD1,CEP68,RGL1,PCDHA5,RUNDC3B,FLRT2,MARCH8" Drug 3230_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "SPARCL1,ALCAM,GAS7,DNAH17,ATP2A2,ALDH7A1,GYG2,BAIAP3,LDLRAD4,CFAP410,CA4,CACNA1A,SLC16A4,PLAA,CNTNAP2,PHF14,ARHGEF4,CDKL3,FGF12,IQCG,NEU3,ALDH1L1,SHISAL1,KCNN1,LSS,MARK1,CNOT4,PLCD1,PPARA,PPP5C,PRKCB,MAPK4,MAPK7,SCN2B,SLC2A5,ARHGEF40,ZNF334,SLC14A1,ZNF415,ARHGAP26,CDK19,PCDHA5,TPM2,RUNDC3B,TRO,GDPD5,KCNAB1,PHTF2" Drug 2203_UP Karakoline [39089-30-0]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "NDRG2,DDO,FAM131A,BCAS1,CDC14B,BMP7,MTMR3,CACNA1I,CHN2,TPP1,ABCG2,CNTN1,CPS1,PDE4DIP,DAPK3,HS3ST2,MBNL2,BAIAP2,FLT1,PRELID3A,POLL,PCLO,C2orf72,KCND1,KCNJ5,MEF2C,MX1,NPR2,NTRK2,PFKFB4,MTRF1L,WDR25,PTPRN2,PID1,STUM,CPEB3,EPN2,SLC6A8,MYH15,SNCA,DOK5,RPGRIP1L,SYNE1,SLC35G2,TPM1,RPRM,UGT8,CLIP2" Drug 3326_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADORA2A,APLP1,PPFIA3,SCAPER,MTMR3,CA4,CBFA2T2,FOXN3,ASIC3,B4GALT6,CREM,PPP6R2,DCAF4,SLC12A6,DTNA,SUGP2,EIF5,ING4,STX2,TXNL4A,GNG4,CNTRL,BTN2A1,KCNH2,KCNJ5,NPTX1,MBOAT7,PRKAR1B,GRAMD1C,PRODH,RGS12,SH3BP2,SYBU,SMARCA4,ZHX3,IQSEC2,SS18,PHLDB1,PLCB1,KIAA1107,TMEM121,SLC44A1,UBTF,VIPR2,KCNK12,XRCC4,ST7,RNF170" Drug 169_UP FK-506; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ASIC1,SEMA7A,APBB2,PPFIA3,RASL11B,MPDZ,BMP7,CA4,TBRG4,ARHGAP32,C2CD2L,DRP2,RCAN1,OPTN,TUBD1,ERBB2,PTK2B,NEU3,SRCAP,RUNDC3A,PSIP1,ACOT7,AGBL5,KCNN1,MBD1,NELL2,RETREG1,SMOX,PMP22,CEP41,MAPK3,CYBC1,TMEM104,NKAIN1,RGS3,TCP11L1,FNDC3A,EPN2,KBTBD4,ZKSCAN3,SMARCD3,CDK19,SPART,CLASP2,CEP68,HEY1,CA14,WIPF1" Drug 2319_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "C1QTNF3,AMPD3,CDC42BPA,APBB2,PPFIA3,BMP7,SYNJ2,CAMK2G,KYAT1,SLIT2,QKI,CSNK1E,PPP6R2,DENND4A,ACSL4,BAIAP2,RNFT2,ELOVL5,ITPKB,KCNN2,TM6SF1,GIT1,ZNF862,NCAM2,PALM,CDK18,PPP2R2B,TMEM104,WDR25,ELOVL2,TMEM231,TRIM68,ROBO1,TCP11L1,SBF1,ZNF821,ANKRD6,BTBD7,KIF13A,KDM4B,ZBTB43,POGZ,PLCB1,TACC1,ZKSCAN5,WIPF1,HPS4,KAT6A" Drug 5811_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ACTN1,GAS7,PPP4R4,ALDH7A1,KIF1A,NRP2,CFAP410,CACNA1A,CBFA2T2,ENTPD2,ARHGEF2,KCNAB3,ARHGAP33,LARGE1,CNOT8,CLTB,RAB26,AKAP7,ARMC8,PDE4DIP,ARHGAP24,GIT2,MYEF2,C2CD2L,OPTN,NCALD,ETV1,TRMO,OGA,ERAP1,NTRK2,SERPINI1,PPP5C,BEND5,KHDRBS2,SALL1,ZNF821,FUZ,AMBRA1,WDR37,PEX26,KDM4D,TMCC1,TRIM2,TLR4,SSBP2,SEMA3B,EPM2A" Drug 4262_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "NDRG2,ADORA1,BBOX1,PPFIA4,AQP6,ATP2B2,MYOM1,KSR1,KALRN,NDST3,NRXN3,NRG2,CSF1,CNTNAP2,EDNRA,ELN,PIPOX,FGFR3,GFER,CSDC2,TOX3,GRIA2,ADAMTS6,IRAK3,HNMT,MGAT3,ADAM22,NF1,NTRK3,PDE4A,RETREG1,PDZRN4,SEPT4,PPP1R1A,DCHS2,PTPRN2,KHDRBS2,SCN2B,ARHGEF40,IZUMO4,CDK19,SYT5,TRO,LAT2,ZNF225,NT5M,NLRP3,GAN" Drug 2655_UP Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ASPHD1,TRMT9B,KCNAB2,APLP1,CDK10,MARK4,USP2,ARHGEF1,ARHGAP33,CBARP,CSF1,ARHGEF10,RASSF2,C2CD2L,SPOCK3,HS3ST2,SEMA4D,AHDC1,MUM1,ATXN2L,LAMA2,MMP17,NPTX1,OPRL1,PLTP,LRP12,PPP1R1A,PRODH,PTPRO,KHDRBS2,RGS12,RPS6KA2,SCN8A,SH3BP2,BTBD7,SPTAN1,IQSEC2,SYN1,ARC,TACR1,TIAM1,PARD3,TSN,VSNL1,WIPF1,KLC2,GDPD5,SEMA3B" Drug 6489_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADD2,APC,GAS7,CAMK2G,CHRNA4,TAOK2,HOMER3,PCYT1B,COL9A3,ABI3BP,CSF1,GREB1,TBC1D5,SPOCK2,MFAP3L,EGR3,RASL12,OLFM1,FGFR1,FHL1,DCTN2,EFCAB2,SRCAP,GPD2,GPER1,GRM8,JAK2,KCNF1,MAN2A2,ADAM22,MTRF1L,RELN,ELOVL2,GTDC1,SBF1,SGK1,FRMPD1,FNDC3A,SYBU,SLC11A1,ZNF423,ST5,DMXL2,TNS1,ZKSCAN5,VGF,WIPF1,SMIM8" Drug 4777_UP Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "RALGAPA1,AP2A2,BEGAIN,AMPD3,PPP4R4,MARK4,CFLAR,SCARB1,ARHGEF2,CHN2,CNTN1,COL9A3,CRMP1,GIT2,DBN1,DMPK,FRY,DENND4A,SPEG,NRN1,ACSL4,FER,BAIAP2,FHL1,GPER1,ADAMTS13,AP4S1,IL6ST,KCNH2,KCNJ5,ADAM22,NF1,SERPINI1,FBXW7,TCP11L1,ASAP3,SLA,SLC2A5,SLC11A1,SMARCD3,SNCA,KDM4B,TCF4,TRIM2,SLC19A3,CRTC1,CHST5,PARP11" Drug 2201_UP Foliosidine [2520-38-9]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "BEGAIN,TRMT9B,BMP7,HAP1,CDH2,KCNAB3,CHN2,ARMC8,SLC4A8,PDE4DIP,RIMS2,ST3GAL6,FLNC,FLT1,EFCAB2,DLL3,TRAF3IP2,INPP5K,ADAM28,RUNDC3A,TJAP1,KCNJ5,KHK,MYCN,NNAT,OPRL1,SLC25A23,MASP1,BCAS3,SUGCT,FBXW7,PKNOX2,SNCA,TMCC1,SS18,ADGRL3,SYNE1,HIF3A,BHLHB9,PARD3,TPM2,RPRM,SH3GLB2,ZNF225,SLC17A7,KCNAB1,KAT6A,NLRP3" Drug 3512_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADORA1,SEMA7A,FAM131A,CFLAR,BTK,CFAP410,RUNX1T1,P2RX6,EPS15L1,FAM149A,ENTPD4,AATK,CSF1R,GREB1,CDON,MTSS1L,ZNF589,FGF13,AFF2,SEPT9,LYVE1,GLYR1,GNG4,PCLO,GRM8,AP4S1,MARK1,AFDN,OPRL1,ENPP2,PLCD1,STRN3,LRP12,PPP2R2B,PPP5C,RGS12,RASA3,ST6GAL1,LIMS2,SNCA,TSNAXIP1,SPTB,CDK19,KIAA1107,WSCD1,PCDHGA10,FLRT2,ZFP37" Drug 3854_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADRA1D,DOC2A,CDC42BPA,GAS7,APOC1,CA12,ARHGAP33,B4GALT6,BAG4,SH2B1,AKAP12,RIMS2,DMPK,FGFR3,ALDH1L1,SRCAP,GFER,PCDH17,POLL,MPP2,ADAM22,NF1,PLCD1,SLC25A23,LRP12,MBOAT7,SNRK,PTPRE,RIPOR1,ZSCAN2,ENOX1,TRIM68,RGS12,CLIP1,FAM214B,BTBD7,LIMCH1,SNCA,FNBP1,TROVE2,COBL,KIAA1107,R3HDM1,TPM1,PLPPR2,LMF1,KCNK12,ZFP37" Drug 6024_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ABHD6,AMPD3,AMT,ARSE,ADGRB3,RGS11,NRP2,CACNA1A,CACNA2D1,HAP1,CAMK2B,CDO1,CHRNA4,CNN3,NRG2,DGKG,ELMO1,DUSP9,SPEG,F5,ADAM28,RUNDC3A,GNAL,GNAO1,PRUNE2,GRM8,ITGA7,KIF5A,NEFM,PFKFB2,LRP12,PPARA,PPP5C,FAT4,KHDRBS2,RFX2,CSRNP3,LIMS2,SMARCD3,LIMCH1,WSCD1,PCDHGA10,HEY1,TIMP4,R3HDM1,SPHK2,NT5M,KCNAB1" Drug 2266_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ACHE,NDRG2,ADCY6,AK2,ALK,SEMA7A,GAS7,ARHGDIG,ADAM23,KSR1,TPP1,MYRIP,CRMP1,NCOR2,CSF1,RUSC2,EIF4G2,MTSS1L,EPHB1,ERCC2,DLC1,OLFM1,FGFR1,SEPT9,GPER1,GRIN2C,GRM8,IRAK3,HLF,KIF5A,MEF2C,PCBP3,GPR85,PFKFB2,PRKCB,CNTLN,C1orf54,KLHL11,FRMPD1,ASAP3,SLA,KANSL3,SLC11A1,ARHGAP26,SYT5,CRTC1,VIPR2,KCNK12" Drug 7319_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "KCNAB2,APC,SEMA4G,MARK4,SYNJ2,MYRF,CACNA1A,CACNA2D2,AKAP7,AKAP6,HDAC9,DENND4A,PDLIM5,DISC1,RUNDC3A,ELOVL5,SCIN,FAM69A,MEIS1,MMP16,NF1,PDE4D,MINDY2,MAPK7,CNNM2,TMEM231,RGS4,NEK11,ZNF821,AMBRA1,PEX26,PPP4R3A,SLC6A8,SLC9A5,SLC14A1,TSNAXIP1,IZUMO4,JMJD6,EXOC7,THRA,TIAM1,TK2,TPM2,OSBP2,VIPR2,WIPF1,SPHK2,EMSY" Drug 4615_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "RALGAPA1,AK2,ADGRF5,ZSCAN18,ALDH7A1,RUNX1T1,SLC16A4,CHN2,TAOK2,CLTB,VAX2,PCYT1B,ENTPD4,VCAN,PDE4DIP,PLXNC1,CALCRL,ZNF549,EZH1,FLT1,GALC,GNAL,PRUNE2,SPACA9,GRIK5,HLF,ICA1,LAMA2,NF1,P2RY1,PCSK5,STRN3,MASP1,SNRK,ZMAT4,RGS12,KCTD17,TRAPPC13,NLGN1,ANKRD6,ARHGAP26,DDN,PHLDB1,KIAA1107,KLHL4,PCDHGB6,VGF,KCNK12" Drug 5448_UP Iopanoic acid [96-83-3]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADGRF5,SEMA6A,CDC14B,PPP4R4,SLC4A4,N4BP2L1,SYNJ2,SLC16A4,CPS1,GREB1,JAKMIP2,SHANK1,DTNA,EDNRA,EGFR,ING4,TNK2,EPHB1,ZNF589,AGAP2,ERAP1,SIGLEC8,NXPH3,ICA1,TJAP1,KCNQ3,KIT,MAP4,MAPT,MGAT3,MID1,PALM,RELN,ZSCAN2,ZMAT4,RFX2,RGS4,ZFHX4,RPS6KA2,SH3GL3,ARHGEF40,KDM4B,DOK5,CDK19,R3HDM1,TRPM2,SLC30A3,PLSCR4" Drug 6699_UP Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "AMH,APAF1,APBB2,APC,ARRB2,PTCH2,BMP7,LDLRAD4,KALRN,RUNX1T1,CHN2,HOMER3,AKAP5,ENTPD4,VCAN,PHF14,DAPK1,C2CD2L,LYPD1,HIPK3,MBNL2,ETV1,FAM198B,ERAP1,SIGLEC8,GPER1,ATXN2L,IL12A,LAMA2,MAN2A2,MIA2,LYRM9,NF1,CNOT4,NOVA2,RGS12,RPS6KA2,ZFP30,CPEB3,DZIP1,SLA,FAM214B,DICER1,THRA,TIMP4,UGT8,ZNF24,SENP7" Drug 2309_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ALK,CDC42BPA,CDK13,RASL11B,SLC4A4,CFLAR,MTMR3,RUNX1T1,CBFA2T2,KCNAB3,ARHGAP33,CHRNA4,TAOK2,EPS15L1,SNCAIP,CNTNAP2,RASSF2,DUSP9,HIPK3,VPS13B,ERCC2,SPEG,F5,CSPG5,ERAP1,DISC1,SRCAP,GFER,GLYR1,LSS,ADAM22,MSR1,ENPP2,PLCD1,PLTP,SAMD9,ACSM5,CCDC40,STUM,CNKSR2,LIMCH1,SNCA,SP4,ATP10B,OSBP2,DNALI1,AP3B2,JPH3" Drug 3860_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADRA1D,AMH,AMPD3,BIN1,CDC42BPA,ARRB1,DNAH17,C5,BAIAP3,CALB2,CAMK2G,CBFA2T2,CRLF1,ARHGEF4,RIMS2,DMPK,DUSP9,NCALD,ZNF589,FGF12,FGFR1,PDLIM5,FAM49B,SRCAP,GFER,GRM8,RASSF8,ELOVL5,ITPKB,NPTX1,RETREG1,PLEC,MINDY2,SNRK,RIPOR1,ENOX1,ZDHHC14,TRIM68,EMID1,SH3BP2,BTBD7,SPTAN1,TROVE2,RGL1,CHST8,TNS1,LAT2,KCNK12" Drug 2464_UP Probenecid [57-66-9]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADORA1,BEGAIN,APBB2,SEMA4G,MPDZ,BMP7,CACNA1I,CA12,THSD7A,CAST,HIP1R,CACNA2D2,SLIT2,ABCG2,CNN3,ABI3BP,CREM,TMCC2,DTNB,EDN3,EDNRB,ERBB4,CDKL3,AGAP2,TMEM8B,KCNJ5,KCNN1,MAP4,MEF2C,NTRK3,PDE4D,CCSER2,RELN,PTPRN2,RGS3,MAP6D1,ASAP3,CCDC92,SLC11A1,DOP1A,HECW1,LHPP,SYT5,TACR1,IQCE,FAM189A1,ZNF32,KCNAB1" Drug 7391_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ASPHD1,ASIC1,ADCY6,NME5,APC,GAS7,CDC14B,DNAH17,MARK4,ATP1A3,SLC4A4,NCOR2,CSF1R,USP6NL,TBC1D5,DPH1,EDNRB,ELN,DENND4A,ETV1,FGF1,FYB1,GFER,ZNF276,GPR75,RNFT2,DHX35,TJAP1,ITPKA,RETREG1,POLG,LRRN3,CNNM2,TMEM104,WDR25,CCDC40,FBXW7,PPP4R3A,SNCA,TSNAXIP1,SPTAN1,ARHGEF9,GPR161,R3HDM1,CABIN1,VIPR2,REEP1,EVI5" Drug 3198_UP Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "BEGAIN,BIN1,KCNAB2,GAS7,PLA2G4C,ATP1A3,AZGP1,CFLAR,RUNX1T1,SLIT2,NRG2,CREM,IPCEF1,CNTNAP2,PHF14,EDN1,PLXNC1,ING4,ZNF549,EYA1,ABCA8,CORO2B,ST3GAL6,CSDC2,GPR12,HLF,INPP5B,AFDN,MSR1,MYCN,ZNF862,NOVA2,GPR85,PPP1R1A,MAPK7,FAM184A,RGS12,SH3BP2,EPN2,SNAP25,PEG10,SPTAN1,CDK19,TCF4,TNS1,TRIO,TUBB1,NT5M" Drug 5529_UP Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADCY6,AK2,PLA2G4C,PDE8B,ATP2B2,ATP6V0A1,NRP2,GYG2,CACNA1I,B4GALT6,AKAP7,DCAF8,TMCC2,SLC12A6,HIPK3,MBNL2,ANKFY1,ADAM28,POLL,GRB10,ADAMTS13,ATXN2L,MAN2A2,NF1,PDE4B,GPR85,SLC25A23,LRP12,PRODH,MASP1,GDPD2,ELOVL2,RIPOR1,TMEM231,C1orf54,ZDHHC14,SH3GL3,FAM214B,SLC11A1,PDZD2,KDM4C,SPTAN1,RBM26,CEP68,STX1A,KIAA1107,DOCK9,LMF1" Drug 5505_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ABR,ABHD6,ADD2,TRMT9B,ADGRB1,CACNA1I,CALB1,ASIC3,CLTB,AKAP7,CPS1,LRIG1,GPRASP1,GSDME,SLC12A6,HEYL,PLXNC1,MTSS1L,CDKL3,PIPOX,NRN1,FHL1,ZNF44,LYVE1,GRIK5,GRM2,KIF5A,LIG4,MAP2,MEF2C,MID1,NF1,P2RX7,MTRF1L,LRRN3,MAPK10,RELN,NEK11,FRMPD1,SYBU,PKNOX2,PDZD2,SPP1,TBCEL,WSCD1,CABIN1,ZNF24,ITM2C" Drug 6505_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADORA2A,SYT13,N4BP2L1,RUNX1T1,CD86,FOXN3,CHGB,CHN2,PLEKHB1,CHRNA4,HOMER3,WHRN,CABP1,ENTPD4,RGS6,ARHGEF10,SNPH,GSDME,DMPK,SHANK1,EDNRA,AASS,C3orf18,HSD17B14,ERCC2,NRN1,ADAMTS13,RASSF8,HLF,SYNPO,JAK2,PACRG,NTRK3,MTRF1L,MAPK7,RASGRF1,RGS12,SBF1,SNCA,DDN,JMJD6,PLCB1,AP4E1,SLC44A1,ZKSCAN5,FLRT2,LAT2,PLSCR4" Drug 3537_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-07 1.28E-02 2.21E-05 2.50E-04 48 199 "ADGRF5,ADAM23,CFAP410,CACNA1A,SLIT2,TPP1,CSF1R,SIPA1L1,CNTNAP2,PHF14,SPOCK3,SLC12A6,EDNRA,PLXNC1,TENM1,TNK2,SPEG,ST3GAL6,AGAP2,MALT1,GNG4,LPAR4,ATXN2L,ELOVL5,IFI16,INPP5B,MEIS2,MGAT3,AFF1,NELL2,PDE1C,PPP5C,PRPH,PTCH1,ZSCAN32,PNMA8A,RPS6KA2,SYBU,LIMCH1,SNCA,ZNF415,KIAA1107,R3HDM1,LMF1,MKRN3,ITM2C,PHTF2,SENP7" Drug 6932_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.20E-07 1.40E-02 2.42E-05 2.73E-04 45 182 "ASPHD1,ABHD6,ARNTL,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,STOML1,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,BAIAP2,PDLIM5,FYN,CYP46A1,RAB40B,STON1,ACOT7,HSF2,MEIS1,MPP2,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,RETREG1,PMP22,PKIA,PRPH,SH3BGR,SH3GL3,WDR47,SLC6A8,ELOVL4,RGL1,STXBP1,HEY1,BEX4,RUNDC3B,SSBP2,GDPD5,SLC17A7" Drug ctd:D012906 Smoke CTD 3.23E-07 1.42E-02 2.44E-05 2.75E-04 157 938 "ASPHD1,ACHE,TMCC3,USP31,AGT,TAOK1,SRPX,BIN1,APBA2,EPB41L5,LGR5,ZFYVE28,PDE8B,BACH1,BCHE,PROM1,DST,SYNJ2,CA12,DDR1,CH25H,CBR1,USP6,SCARB1,ARHGEF2,CDH2,B4GALT6,RPL32P3,ABCG2,GDA,AATK,SNCAIP,CSF1R,SUSD5,VCAN,SLITRK5,PITPNM3,PPP1R16B,GREB1,RIPOR2,SNPH,DGKG,SPOCK2,AIF1L,GIT2,ARMCX4,ARMCX2,MYEF2,DYNC1I1,DOCK2,EDNRA,EDNRB,RASGRP1,EGFR,RGS17,PCOLCE2,ETV1,ABCA8,SH3YL1,PTK2B,ST3GAL6,FCGR3A,FGF13,FLNC,SYT3,SPECC1,RASL10A,GALNT15,B4GALNT1,SYT17,DISC1,ACSS1,GCNT2,SRCAP,PPARGC1A,MAP7D2,PCLO,ZNF496,GSN,GUCY1B1,ATOH8,PADI2,NEGR1,IGF1,KCNJ16,L1CAM,NCOA7,GPR155,MATN2,MBP,MEF2C,SAMD5,MSR1,MX1,MYO6,BEX5,NEFH,NFE2L2,NME4,NOVA1,NRCAM,OGG1,CLDN11,OXTR,PALM,PDE4B,ABCB1,SERPINI1,PIK3C2A,PIK3R1,PLXNB1,EPB41L4B,FA2H,SH3KBP1,MAPK3,EPDR1,KLK6,LAMA1,PTCH1,ELOVL2,SPDL1,ZIK1,ACSS3,FAM66C,MRAP2,SNX22,FBXW7,MAPK12,SEC14L1,MRAS,CPEB3,ST6GAL1,ABLIM3,SIRT2,SLC22A4,ZNF415,PDZD2,SOX15,SPP1,UNC5B,KANK1,SULF2,SYNE2,SYT1,COBL,SATB2,SIRT1,CHST8,TLR4,TPM2,TRO,UCHL1,FLRT2,TCEAL7,REEP1,TTC7A,DPF3" Drug 3177_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.29E-07 1.44E-02 2.48E-05 2.79E-04 46 188 "ABHD6,SYT13,APLP1,CDC14B,BMP7,ST3GAL5,RAB29,CLGN,UBE2L6,FAM149A,CABP1,ARMCX2,TSPAN5,MBNL2,ACSL4,IQCG,FYN,CYP46A1,STON1,MITF,MPP2,NEK1,SERPINI1,PMP22,DIRAS2,PRPH,GAL3ST4,RPS6KA2,RPS20,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,SPTAN1,ELOVL4,RGL1,STXBP1,PLCB1,HEY1,RUNDC3B,SSBP2,REEP1,SLC30A3,GDPD5,SLC17A7" Drug 4616_UP Bisacodyl [603-50-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.29E-07 1.44E-02 2.48E-05 2.79E-04 46 188 "AMPH,KCNAB2,PPP4R4,KSR1,SYNJ1,CA4,CA8,ARHGAP33,DLGAP1,SOCS6,CRMP1,CRYBB1,CTH,RIMS2,DRP2,DTNA,EDNRA,EPHB1,AGAP2,PRELID3A,CHL1,SIGLEC8,GNG4,GPD1,VSIG4,ELOVL5,MBNL1,MSR1,NF1,STRN3,RGS12,EMID1,RTN1,SCN2B,CNKSR2,SLA,KANSL3,SNCA,ZBTB43,PHLDB1,ARC,SYT5,ANKRD12,RUNDC3B,VGF,VIPR2" Drug 5050_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "ASIC1,ADRA1D,C1QTNF1,TRMT9B,EPB41L5,APLP1,LGR5,CDC14B,TAOK2,RAB28,NRG2,ENTPD4,HAPLN1,CSF1R,ARHGAP24,KLHL3,MRNIP,CDKL3,BAIAP2,SCARA3,SEPT9,SRCAP,KIF2A,MAPT,MEF2C,MT1M,PDE1C,CCSER2,PLXNB1,MAPK7,ZSCAN2,TMEM231,RPS6KA2,RXRA,FNDC3A,PPP4R3A,SIRT2,FNBP1,FBXW11,TIAM1,TRIO,OSBP2,LMF1,WIPF1,MAP3K12,EVI5,KAT6A" Drug 4951_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "NDRG2,NME5,ALK,PPFIA3,MARK4,SLC2A11,CAMK2G,CBFA2T2,ARHGAP33,CHRNA4,SULT4A1,CSF1R,DCAF4,SPOCK2,BRINP1,C2CD2L,CORO2B,FYB1,ALDH1L1,TJAP1,KCNH2,MAP4,AFDN,NOVA2,PCDH9,MTRF1L,ZNF493,ZMAT4,KCNIP1,SLC2A5,PKNOX2,ZNF415,DOP1A,ZC3H13,SPTB,IQSEC2,TBCEL,SMG6,WSCD1,PCDHGA10,HIF3A,THRA,TK2,VIPR2,WIPF1,SLC30A4,SLC17A7" Drug 2546_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "CDC42BPA,ATP1A3,MYOM1,BAIAP3,SLC16A4,CHRNA4,VAX2,RAB26,ABI3BP,RGS6,DZIP3,ARHGEF4,BRINP1,TMCC2,EDN3,AASS,APC2,EYA1,AFF2,SIGLEC8,SEPT9,GATM,LYVE1,TOX3,GNG4,AP4S1,PADI2,KCNJ5,ADAM22,PPP1R1A,RGS12,SUGCT,SCN2B,ZFP2,CCDC92,SLC11A1,ZNF415,PEG10,SYT5,PCDHGB6,PCDHGA10,PHF24,SLC19A3,TK2,TNS1,WNT7A,JPH3" Drug 2998_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "SYN3,ABHD6,CDC42BPA,APBB2,RASL11B,CACNA1I,CFAP410,CAMK2B,KCNAB3,CHN2,AKAP6,CSF1,PDE4DIP,SPOCK2,EDN3,OPTN,ING4,ETV1,EYA1,BAIAP2,KHDRBS3,NSG1,GPR162,ADAM28,LILRA2,SPACA9,GRIK5,SYNPO,KCNB1,LAMA2,MYO6,OPRL1,OXTR,GPR173,PFKFB4,PLCL1,PILRA,RGS4,EMID1,CXXC4,SMARCD3,KDM4B,IZUMO4,TBCEL,ZNF34,SSBP2,KCNAB1" Drug 6424_UP F0447-0125; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "BIN1,GAS7,ARNTL,RASL11B,CFLAR,CA4,SCARB1,FOXN3,PLAA,QKI,AKAP7,WHRN,CREM,RIMS2,CYBB,DAPK3,JAKMIP2,DTNA,EIF4G2,ING4,ETV1,FGF1,AGAP2,GAD1,DISC1,RUNDC3A,STMN2,RASSF8,ICA1,IL6R,ITPKB,MEF2C,ZNF862,NCF2,NFYA,C1orf54,SATB1,SLC6A8,BTBD7,SS18,WSCD1,TRIM2,AP4E1,ZNF34,HEY1,LMF1,ZFP37" Drug 4281_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "ADD1,AK2,CDK13,CFLAR,CA12,FOXN3,VCAN,PDE4DIP,PLPPR4,DTNA,FEM1B,FCF1,MBNL2,ERCC2,SCARA3,HPCAL4,PDLIM5,TRAF3IP2,MSL3,POLL,RASSF8,AGFG1,IL6ST,INPP5B,NFIX,NLE1,STRN3,PPP5C,SNRK,SLC25A36,ZFP30,PPP4R3A,CCDC88A,ZNF667,SP4,SLC44A1,THRA,TK2,TMPO,R3HDM1,RPRM,VIPR2,XRCC4,ZNF74,EVI5,KCNAB1,KAT6A" Drug 4662_DN Menadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-07 1.48E-02 2.51E-05 2.82E-04 47 194 "EP400,APBB2,FAM131A,SHROOM2,CDK13,EIF4G3,KRIT1,ABI3BP,SLITRK5,RUBCN,DOCK4,DBT,KLHL3,MAMLD1,FCF1,STX2,FGFR1,IFI16,FAM69A,SCAMP5,CNOT4,NPR2,PIK3R1,SNRK,PID1,GTDC1,NUBPL,WDR37,PDZD2,PEG10,TROVE2,TTBK2,DIP2A,VPS13A,SYT1,FAM208A,TBL1X,TMPO,TRIO,SSBP2,HIRA,ZBTB14,NDRG4,NAV3,MPPE1,FZD3,UBE3B" Drug 4953_UP Nifurtimox [23256-30-6]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ASPHD1,AP2A2,NME5,LTBP4,BIN1,FAM131A,ARHGDIG,CHRD,SLC4A4,CBFA2T2,ARHGEF2,ARHGAP33,HOMER3,SH2B1,RUBCN,ELMO1,MFAP3L,RUSC2,PARD6A,EDN3,MTSS1L,GATM,GCNT2,SRCAP,PCLO,NEFM,CNOT4,PCBP3,P2RY1,PPP2R2B,VPS13C,PTH1R,KLHDC8A,DZIP1,PKNOX2,CXXC4,PLCB1,SYN2,SMG6,WSCD1,TCF4,DOCK9,CABIN1,TRIO,XRCC4,ZNF711,SLC30A3,SEMA3B" Drug 2199_UP Myosmine [532-12-7]; Up 200; 27.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "APBB2,ARHGDIG,PLA2G4C,PDE8B,ATP2B2,KSR1,CFAP410,ARHGAP33,CNN3,CNTFR,PDE4DIP,RIMS2,DCAF4,CDON,EDIL3,EDNRA,PLEKHA1,ANKMY1,FECH,FGF12,AGAP2,IQCG,PDLIM5,SIGLEC8,INPP5K,GFER,GNAO1,KCNJ5,KIF5A,MAP4,MSR1,PCDH9,PLCD1,SLC25A23,EPB41L4B,POU6F1,WDR25,PTPN13,STUM,PEX26,SLC9A5,STX1A,SYNE1,CRTC1,DICER1,FLRT2,SPHK2,PLSCR4" Drug 5784_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ADORA1,SLC4A4,ATP2B2,KSR1,BAIAP3,CD86,CHN2,ARHGAP22,PLAA,LY86,HOMER3,AKAP5,ABCG1,DBT,PLPPR4,EDN1,CNNM1,FGF1,PRELID3A,FYB1,SRCAP,LILRA2,STON1,CNTRL,GSN,ELOVL5,KCNB1,KCNJ5,MAN2A2,AFF1,TAGLN3,NRCAM,PDE4D,PPP2R2B,ACSS3,KCTD17,ZNF821,STUM,SNCA,PDZRN3,KDM4B,ARHGAP26,MCF2L,TRIO,WIPF1,EVI5,SEMA3B,DPF3" Drug 6970_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ADRA1D,FAM131A,APOC1,BCAS1,GYG2,CBARP,SOCS6,B4GALT6,ENTPD4,FAM169A,DBN1,MED12,CDON,PHF20L1,EGR3,EIF4G2,RRAGB,FER,ANKFY1,DISC1,SPACA9,INPP5B,ITPKB,KPNA5,MAPT,PPARA,MAPK7,WDR25,ZSCAN32,GTDC1,GSTCD,SBF1,ASAP3,DZIP1,EPN2,SPTAN1,SPART,RPGRIP1L,TK2,TPM1,PLPPR2,VIPR2,ZNF711,REEP1,MAP3K12,EMSY,ITM2C,ST7" Drug 6753_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ADGRF5,EPB41L5,GAS7,SLC4A4,MTMR3,CFAP410,CAMK2A,HIP1R,SYNGR3,ARHGAP33,CACNA2D2,SUSD5,DAPK3,C2CD2L,PLPPR4,SGSM2,DMPK,ING4,COQ7,APC2,FLT1,AFF2,TMEM8B,SIGLEC8,GNAL,PADI2,MSI1,MX1,NOVA2,OGG1,P2RY1,POLG,DCHS2,PTPRN2,TMEM231,RET,ZFP30,SLA,SLC9A5,ZC3H13,SPTAN1,CEP68,PCDHGA10,TK2,TPM2,PARP11,EPM2A,DPF3" Drug 2894_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ASIC1,ALCAM,CDK13,SLC2A11,GYG2,CA4,HAP1,FOXN3,CHN2,VCAN,CNTNAP2,JAKMIP2,TMCC2,FRY,EGFR,MBNL2,IQCG,NSG1,SRCAP,PRUNE2,GPER1,KCNN2,LMO2,NF1,NPTX2,PDE4B,SLC25A23,LRP12,VPS13C,ZSCAN2,KCTD17,NEK11,SH3BP2,KANSL3,BTBD7,COA1,KDM4C,IQSEC2,ARC,DMXL2,R3HDM1,TPM2,RUNDC3B,TRO,XRCC4,NT5M,EVI5,ITM2C" Drug 2011_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ASIC1,ADORA1,C1QTNF1,SPARCL1,APBB2,EIF4G3,BCL7A,SLC25A14,CD86,CREM,CRY2,AATK,C2CD2L,TUBD1,KAT8,TMEM164,SUCO,KCNMB4,AGFG1,TJAP1,MYO5A,NF1,OCRL,PFKFB3,RETREG1,NLE1,POLG,MINDY2,MAPK10,MASP1,SNRK,KLHDC8A,STUM,SH3BP2,BTBD3,KBTBD4,SLC12A2,ELMO2,SPTB,SPART,POGZ,FAM208A,CRTC1,R3HDM1,NPL,HIRA,TRIM9,EVI5" Drug 6829_DN Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-07 1.50E-02 2.51E-05 2.83E-04 48 200 "ALCAM,MARK4,CFLAR,ST3GAL5,SYNJ2,FOXN3,CREM,SH2B1,CRY2,NCOR1,HDAC4,SLC12A6,DTNA,TOM1,EDNRA,SUGP2,RRAGB,FER,OGA,SRCAP,GRB10,BTN2A1,INPP5B,ITPKB,JAK2,KCNH2,MAP4,GIT1,NFYA,PRODH,RGS12,CCDC25,RPS6KA2,SBF1,SGK1,SH3BP2,COA1,SNCA,SPTAN1,PHLDB1,EXOC7,IQCE,ZNF34,BHLHB9,TPM1,PLPPR2,GDPD5,HPS4" Drug 3312_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.67E-07 1.61E-02 2.68E-05 3.02E-04 44 177 "NME5,ALCAM,ST3GAL5,BAIAP3,CLGN,DOCK4,ARMCX2,JAKMIP2,TSPAN5,FAM13A,RASGRP2,HPCAL4,OGA,FYN,CYP46A1,RAB40B,STON1,NEK1,PCDH9,SERPINI1,PLCD1,PMP22,PKIA,GRAMD1C,PRPH,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,ARHGEF40,ELOVL4,RGL1,STXBP1,TRIM2,RPGRIP1L,HEY1,RUNDC3B,SSBP2,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 6493_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.67E-07 1.61E-02 2.68E-05 3.02E-04 44 177 "NME5,ARHGDIG,MARK4,ST3GAL5,CACNA1G,BAIAP3,CLGN,DOCK4,ARMCX2,FAM13A,FYN,CYP46A1,RUNDC3A,RAB40B,STON1,PADI2,FAM69A,KCNN2,MXI1,SERPINI1,PKIA,GRAMD1C,PRPH,GAL3ST4,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,SYBU,WDR47,FAM214B,PKNOX2,CCDC88A,ELOVL4,RGL1,STXBP1,ZEB1,TRIM2,HEY1,RUNDC3B,SLC30A3,SLC17A7" Drug 3462_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.67E-07 1.61E-02 2.68E-05 3.02E-04 44 177 "NME5,ALCAM,ST3GAL5,BAIAP3,CLGN,PDE4DIP,ARMCX2,TSPAN5,OPTN,FYN,CYP46A1,RAB40B,STON1,RNFT2,FAM69A,MITF,ZNF862,NEK1,PCDH9,TMOD2,SERPINI1,PMP22,PRPH,ROBO1,RPS6KA2,SH3BGR,SH3GL3,PPM1E,ASAP3,WDR47,FAM214B,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SSBP2,ZNF45,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug ctd:D010862 Pilocarpine CTD 3.70E-07 1.62E-02 2.69E-05 3.04E-04 62 286 "ASIC1,ACHE,ADORA1,ADORA2A,ADRA1B,SPARCL1,APLP1,ATP2A2,BCHE,CACNA1A,CACNA1B,CALB2,CDH2,SLIT2,CNN3,CNR1,AKAP5,DMD,DPYSL2,ABCC5,EGFR,EGR3,PTK2B,GABRG2,GAD1,ZNF274,GRIA2,GRIK5,GRM2,GRM8,KCNN1,KCNN2,KCNN3,LAMP2,MEF2C,NPY,NOVA1,NOVA2,NPTX2,NTRK2,NTRK3,OGG1,P2RX7,PCSK1,ABCB1,POLG,PRKCB,MAPK3,PTK2,QDPR,RET,S100B,SCN2B,SCN8A,SLC6A11,SLC12A2,SSTR1,SSTR2,SYP,SIRT1,VGF,SLC17A7" Drug ctd:D000726 Androgen Antagonists CTD 3.80E-07 1.67E-02 2.77E-05 3.12E-04 25 75 "ACTN1,CASK,CACNA1I,CACNA1G,CACNA2D1,CAMK2B,CACNA2D2,SHANK1,ERBB2,ERBB4,GRIA2,GRIN2D,NF1,NRCAM,NTRK2,NTRK3,CNTN3,RELN,ROBO1,HES6,NLGN1,STXBP1,TSC2,VLDLR,SLC17A7" Drug 4430_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.88E-07 1.70E-02 2.81E-05 3.16E-04 46 189 "ADD2,BEGAIN,SEMA7A,BCAS1,SLC2A11,BACH1,HAP1,RUNX1T1,CBS,LDB2,CRY2,CTH,GIT2,DTNA,EDN1,SEMA3D,ABCA8,OLFM1,ERAP1,GSTM5,SYNPO,KCNN2,LSS,MMP16,NF1,NPY,NPTX2,OXTR,PALM,PDE4B,PURG,PRKAR1B,PTCH1,MARCH1,RASGRF1,RGS12,RNASEL,KCNIP1,SCN8A,HSPA4L,HKDC1,SLC11A1,RBM34,PDZD2,HECW1,PARP11" Drug CID003036959 PDEs Stitch 3.95E-07 1.73E-02 2.81E-05 3.16E-04 33 116 "ADCY5,ADCY6,ADCY8,ADRB2,PDE8B,ALDH7A1,CALM1,KRIT1,LRBA,CHGB,AKAP7,AKAP6,AKAP5,CREM,ABCC5,PPP1R1B,AKAP3,DISC1,GUCY1B1,MAP4,NPR2,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,EXOSC10,PRKACB,MAPK7,ZNF106" Drug 5269_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NDRG2,SEMA4G,PLA2G4C,DNAH17,KIF1A,CFLAR,SYNJ2,CA4,FOXN3,VAX2,PDE4DIP,EXOG,MBNL2,ING4,COQ7,FGF13,TDRKH,GPER1,CACFD1,RNFT2,SLC2A6,ATXN2L,ELOVL5,IL6ST,KIF5A,MMP16,MPP2,GIT1,ADAM22,ZNF862,PPP2R2B,PRKAR1B,ZDHHC14,RGS12,CARF,ZNF821,PREX2,SLC6A8,ZNF430,CXXC4,ZHX3,PHLDB1,AP4E1,TK2,VLDLR,KCNK12,EVI5" Drug 5774_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "AP2A2,DOC2A,PPFIA4,EPB41L5,ATP6V0A1,LDLRAD4,RUNX1T1,USP2,FOXN3,CHRNA4,TAOK2,STOML1,HOMER3,CNTFR,PDE4DIP,SV2B,EDIL3,CELSR3,COQ7,ZNF391,EZH1,PDLIM5,GATM,SRCAP,CSDC2,GPD1,PRUNE2,SPACA9,GRIK5,CACFD1,GRM2,IGF1,MSI1,ADAM22,TAGLN3,NRCAM,PFKFB4,PID1,C1orf54,SLC11A1,HECW1,NFASC,RPGRIP1L,OBSL1,TPM1,CHST5,SENP7" Drug 3478_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NDRG2,SLC4A4,BMP7,GYG2,LDLRAD4,SOCS6,RCHY1,CSF1R,SIPA1L1,ARHGEF4,RIMS2,GPRASP1,DCAF8,DGKG,GIT2,HIPK3,EGFR,MBNL2,HSD17B14,ACSL4,ZNF589,SCARA3,EFCAB2,TPK1,ERAP1,ELOVL5,INPP5B,MAN2A2,TM6SF1,ADAM22,NF1,NPR2,PLXNB1,MAPK7,GTDC1,RNASEL,RPS6KA2,PKNOX2,BTBD7,COA1,ZBTB43,SYN2,EXOC7,TBL1X,KIAA0930,SLC44A1,EMSY" Drug 3173_DN Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "C1QTNF3,DOC2A,APOC1,CDC14B,CDK10,SEMA4G,MARCH3,MARK4,RASL11B,SLC4A4,ATP6V0A1,BCL7A,SOCS6,AKAP7,CRY2,LRIG1,SIPA1L1,CYBB,CNNM1,ENO2,ANKMY1,FGFR1,PRELID3A,ZNF44,TDRKH,LPAR4,DHX35,KHK,MIA2,KITLG,NNAT,CNOT4,PLXNB1,PRKAR1B,ZCWPW1,CEP68,STX1A,SMG6,TNS2,CRTC1,ZNF34,THRA,CABIN1,TRIO,RUNDC3B,GDPD5,EPM2A" Drug 3991_UP Carbarsone [121-59-5]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "PKP4,PPFIA3,PPP4R4,STX16,NRP2,CACNA1I,CACNA2D1,CBS,MTMR7,CBFA2T2,ENTPD4,HAPLN1,CSF1R,LRIG1,SUSD5,CNTNAP2,SEC14L5,DUSP9,ZNF391,NRN1,ZMYND10,MSTN,ADAM28,PADI2,KHK,MAN2A2,TM6SF1,MMP16,ADAM22,NF1,PCSK5,LRRN3,DIRAS2,FUZ,PREX2,SNCA,PDZRN3,RBM26,EXOC7,OBSL1,TNS1,PDIA2,VGF,VIPR2,ZNF24,PHTF2,DPF3" Drug 4251_DN Antipyrine [60-80-0]; Down 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "APOC1,ATP1A3,KIF1A,ADAM23,ADGRB2,CFLAR,MYRF,CBFA2T2,TAOK2,RAB26,DTNA,EGFR,MBNL2,PLXNC1,HSD17B14,COQ7,MTSS1L,ST3GAL6,ZNF589,SEMA4D,ANKFY1,FYN,ZNF44,RUNDC3A,GPD2,LPAR4,GUCY1B1,KCNN1,PALM,PLXNB1,PPP5C,PRKAR1B,ELOVL2,PTPRB,FRMPD1,FAM214B,ZNF667,IFT122,DOK5,IQSEC2,SS18,ASTN2,TPM2,LMF1,REEP1,TFIP11,KCNAB1" Drug 4167_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NDRG2,ADRA1D,AMPD3,EPB41L5,GAS7,MARK4,SGCE,CFAP410,CA4,SPAG9,FOXN3,PDE4DIP,FAM169A,DCAF4,TBC1D5,SPOCK2,PLXNC1,ELN,VPS13B,ERCC2,SEPT9,LYVE1,GLYR1,MSL3,CACFD1,INPP5B,KCNN1,LSS,KITLG,MPP2,MYT1,NF1,MBOAT7,PRKCB,GSTCD,SH3BP2,ASAP3,PREX2,LIMS2,THSD1,PLCB1,SYT5,CRTC1,CHST8,AP4E1,TRPM2,KAT6A" Drug 3376_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NME5,BIN1,EPB41L5,APLP1,FAM131A,RGS20,MARK4,SCAPER,HAP1,USP2,CACNA2D2,STOML1,DTNA,HIPK3,SUGP2,FGFR1,SCARA3,SEMA4D,FAM49B,OGA,ALDH1L1,ZNF276,GSN,IL6ST,JAK2,MBD1,MIA2,KITLG,PALM,PCDH9,PDE4A,LRP12,PPP5C,PTPRO,ZFHX4,FBXW7,TCP11L1,FAM214B,PKNOX2,SIRT2,TSPYL2,ST5,DMXL2,ZNF45,REEP1,DNALI1,SMIM8" Drug 4180_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "ABHD6,ADCY6,LTBP4,SEMA7A,APBA2,GAS7,MARK4,SLC16A4,CACNA2D2,CLTB,WHRN,SH2B1,CRY2,TMCC2,SLC12A6,EGFR,PLXNC1,ELN,ERCC2,OLFM1,FHL1,GAD1,SEPT9,SRCAP,AHDC1,LYVE1,GRIK5,ICA1,TJAP1,INPP5B,KCNH2,MAP4,MMP16,MYT1,NF1,CDK18,PLCD1,SAMD9,RIPOR1,ZSCAN2,DOK5,TSPYL2,THSD1,STX1A,ARC,TRPM2,WIPF1" Drug 6245_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NDRG2,GAS7,APLP1,BCL7A,BAIAP3,CAMK2G,EPS15L1,RAB28,VAX2,QKI,SULT4A1,HOMER3,PDE4DIP,HDAC4,EDN3,EGR3,TNK2,CNTRL,SPACA9,INPP5B,KCNB1,ADAM22,RETREG1,MAPK7,CEP97,KHDRBS2,GSTCD,KCNIP1,SGK1,FNDC3A,SYBU,NLGN1,SNCA,ZHX3,ARHGAP26,SPTAN1,CDK19,PLCB1,ASTN2,ANKRD12,EXOC7,TNS2,CABIN1,TSC2,PLPPR2,SPHK2,SEMA3B" Drug 3977_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "RALGAPA1,ASIC1,ADORA1,AP2A2,AMPD3,SEMA7A,KCNAB2,GAS7,RGS20,PDE8B,MARK4,CFAP410,SLC16A4,ARHGEF1,CLTB,RIMS2,RUSC2,DMPK,DUSP9,HIPK3,FER,SRCAP,RUNDC3A,KIF5A,MAN2A2,MPP2,MSR1,CDK18,PLCD1,STRN3,MINDY2,MAPK7,PTPRD,EMID1,SEMA6D,ZNF821,PREX2,TSNAXIP1,SP4,ATP10B,THSD1,CRTC1,SLC35G2,RUNDC3B,HIRA,LAT2,ZFP37" Drug 6172_UP 17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "SYN3,ALK,SYT13,BIN1,ARSE,SLC4A4,THSD7A,HIP1R,CBFA2T2,COL4A5,FAM169A,SNPH,ARHGAP24,DGKG,SPOCK2,MFAP3L,SV2B,HS3ST2,FAM13A,MBNL2,PLXNC1,MRNIP,VPS13B,REEP2,AFF2,GABRG2,SEPT9,MYO6,P2RY13,OPRL1,CLDN11,PDE4A,MASP1,PTPRD,PTPRN2,KCTD17,HSPA4L,PPM1E,SLC11A1,CLSTN2,ASTN2,DMXL2,TRIM2,HIF3A,UBE3A,LMF1,PLSCR4" Drug 3670_DN Kawain [500-64-1]; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "PKP4,APAF1,CDK13,SLC4A4,NRP2,CFAP410,HAP1,LARGE1,CACNA2D2,RAB26,NCOR2,PDE4DIP,ZNF337,PLPPR4,PARD6A,CDON,MBNL2,ZNF589,FGF1,SCARA3,PDLIM5,GLYR1,HTATSF1,KCNJ5,MN1,GIT1,ZNF862,PCDH9,MINDY2,PID1,ACSS3,ENOX1,SCN8A,SH3BGR,PREX2,CDK5RAP2,LHPP,SS18,ARC,TBL1X,TIMP4,TK2,RUNDC3B,RPRM,KCNAB1,PCBP4,PHTF2" Drug 4194_UP Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.96E-07 1.73E-02 2.81E-05 3.16E-04 47 195 "NDRG2,BEGAIN,APAF1,FUBP1,SCAPER,MYRF,LDB2,MAGI1,FOXN3,STOML1,HOMER3,CTH,SPOCK2,NRN1,PTK2B,GALC,DISC1,TDRKH,STON1,GRM2,KIT,MEF2C,LYRM9,NF1,PCBP3,NTRK2,ENPP2,GPR85,PFKFB2,LRRN3,PRKAR1B,GAL3ST4,RGS4,SEMA6D,STUM,SUPT20H,SH3BP2,DZIP1,SNCA,SP4,SPTB,MCF2L2,SYN2,KIAA1107,PCDHGB6,LMF1,WIPF1" Drug 3979_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.19E-07 1.84E-02 2.97E-05 3.34E-04 43 172 "ADRB2,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,STOML1,WHRN,AKAP12,CRYM,PDE4DIP,ARMCX2,FAM13A,AASS,FGFR1,BAIAP2,FYN,CYP46A1,STON1,KCNB1,MAP2,MPP2,TMOD2,SERPINI1,PRPH,RADX,GAL3ST4,NUDT11,SH3GL3,ASAP3,PKNOX2,ARHGEF40,SOX15,NMNAT2,ELOVL4,RGL1,STXBP1,HEY1,RUNDC3B,ZNF225,SLC30A3,SLC17A7" Drug 6901_UP scriptaid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-07 1.96E-02 3.15E-05 3.55E-04 45 184 "APLP1,MARK4,BMP7,RAB29,BAIAP3,AKAP12,PDE4DIP,ARMCX2,OPTN,MBNL2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MPP2,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PKIA,PRPH,PTCH1,RPS6KA2,SH3BGR,SH3GL3,SYBU,WDR47,FAM214B,PKNOX2,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,RPRM,ZNF23,SLC17A7,ITM2C" Drug 3643_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.46E-07 1.96E-02 3.15E-05 3.55E-04 45 184 "AGT,NME5,MARK4,RGS9,ST3GAL5,GYG2,BAIAP3,CLGN,PDE4DIP,SPOCK2,ARMCX2,FRY,FAM13A,MBNL2,AASS,RASGRP2,FYN,CPLX2,CYP46A1,GFER,GLI2,STON1,KCNB1,KIF5A,MEF2C,MN1,TMOD2,SERPINI1,PLTP,PRPH,ENOX1,SATB1,SH3GL3,ASAP3,PKNOX2,SST,RGL1,STXBP1,TRIM2,SYNE1,GPR161,HEY1,RUNDC3B,SLC30A3,SLC17A7" Drug 6979_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.56E-07 2.00E-02 3.18E-05 3.58E-04 46 190 "BIN1,GAS7,BCAS1,BAIAP3,CRY2,DMPK,DNAJB6,MBNL2,EIF5,COQ7,RASGRP2,SPEG,FAM198B,ANKFY1,CNTRL,SPACA9,CACFD1,INPP5B,KCNJ5,MAP4,MBD1,KITLG,NF1,PALM,PRKCB,KLK6,SAMD9,PTPRN2,FAM184A,HSPA4L,SH3BGR,NLGN1,PREX2,UNC5B,CLSTN2,WSCD1,PCDHA6,TPM1,FAM155A,VIPR2,VLDLR,LAT2,WNT7A,XRCC4,ZNF74,FXR1" Drug ctd:D005419 Flavonoids CTD 4.58E-07 2.01E-02 3.18E-05 3.58E-04 184 1142 "ACADM,ASIC1,ADCY6,ADORA2A,ADRA1D,AGT,SYT13,AMPD3,PPFIA4,APAF1,GAS7,BCAS1,AQP6,ARNTL,ARRB2,ASPA,ATP1A3,SLC4A4,AZGP1,BARD1,BBS2,BCHE,SYNJ1,SYNJ2,DDR1,CACNA2D1,KALRN,CAPN3,HIP1R,RGN,P2RX6,SCARB1,CD38,ENTPD2,SEPT7,DCLK1,COPB2,CHGB,CHN1,CHN2,RAB28,TPP1,NGEF,ABCG2,RAB26,CDC42BPB,HAPLN1,CRYBB1,GDA,SIPA1L1,GALNT9,CST3,CYBB,MATR3,DGKB,BRINP1,DBN1,DBT,SPATA2,DCTN1,DNM1,NR1D2,CDON,DRP2,PDCD6IP,E2F5,OPTN,CELSR3,EIF5,TNK2,STX2,SPEG,CDKL3,RRAGB,PTK2B,POLR1B,BAIAP2,EVL,FLT1,PDLIM5,CGREF1,ST6GALNAC3,DLL3,SARAF,GABRG1,NEU3,MSTN,ARFIP1,PPARGC1A,CRCP,GNAO1,GPD2,ADAP1,PLCD4,GSTT2,NXPH3,PACSIN2,HNMT,NEGR1,IDH3A,IDH3B,IGF1,ITGA7,ITGAM,KCNB1,KCNH2,KCNJ16,KCNN2,KCNN3,MAT2A,MYO5A,NEFM,NINJ2,NNAT,NRCAM,NTRK2,NUCB2,SETD4,OPA1,CLDN11,OXTR,PCSK5,NLGN3,PKD1,PLCD1,NECAB2,POLR2F,PPP1R1A,PPP2R2C,PPP3CA,PRKCB,MAPK10,PRPH,KLK6,PTCH1,PTK2,PTPRO,PEX2,QDPR,CRTAC1,RGS3,RGS4,RPL15,RTN1,ZNF354C,STX1B,SCN7A,SMPD3,ST6GAL1,NLGN1,SEC31A,SLC12A2,SNAP25,SNCA,LMBRD1,SNRPN,PDZD2,SOX11,SPP1,DDN,SAMSN1,SSTR2,MPRIP,STX1A,SEPT3,NECAB1,SYN2,SYT5,MLST8,TCF4,ZMAT3,THRA,TLR4,TST,UBC,UCHL1,UGT8,VIPR2,VSNL1,P2RY12,CLIP2,KCNK12,DPYSL5,RTN4" Drug ctd:D005038 Ethylnitrosourea CTD 4.59E-07 2.01E-02 3.18E-05 3.58E-04 63 294 "AP2A1,ALK,APC,EPB41L5,BLM,DST,CACNA1A,LARGE1,CACNA2D2,CHGB,LHX2,PLAA,QKI,HECTD1,DMD,MED12,RCAN1,EDN3,EDNRB,EGFR,EMX2,STX2,ERBB2,ADGRV1,FDFT1,FECH,FOXF2,POMT1,GCK,FREM1,GRM8,ITPKB,KIT,LAMA2,MBD1,AFF1,MYO5A,MYO6,MYO7A,MYT1,NFIX,NFYA,NTRK2,OPRL1,PAX6,PCSK5,NLGN3,PKD1,PMP22,PPARA,RELN,RASGRF1,SCN8A,SGK1,SLC6A8,SPP1,SYP,TEK,DICER1,SIRT1,ZFPM2,ZIC2,IFT88" Drug 6194_UP genistein; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "SYN3,C1QTNF3,BIN1,ANK2,AQP6,PLA2G4C,ARSE,CFAP410,RUNX1T1,CHN2,CREM,AATK,CSF1,SIPA1L1,PDE4DIP,INTS1,SPOCK3,HS3ST2,MBNL2,MRNIP,VPS13B,RASGRP2,ERBB2,OLFM1,HPCAL4,AGAP2,NSG1,SIGLEC8,MSL3,GPD2,NNAT,NRCAM,DUSP26,EPB41L4B,RGS4,RGS12,SLC11A1,SNCA,IZUMO4,ZC3H13,ST5,JMJD6,TK2,LMF1,VSNL1,MARCH8,JPH3" Drug 3253_UP Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ABHD6,NDRG2,ADORA2A,C1QTNF3,LTBP4,TRMT9B,RGS20,SYNJ1,B4GALT6,PICK1,RIMS2,HDAC9,EDN1,HEYL,EGFR,SEMA4D,FYB1,GCNT2,INPP5B,KCNH2,GIT1,ZNF862,NF1,NTRK2,PLCD1,GRAMD1C,DCHS2,CNNM2,ZFHX4,TCP11L1,SH3BP2,PPM1E,ASAP3,TROVE2,PHLDB1,ARC,SYNE1,SLC19A3,TP53BP1,WIPF1,SPHK2,SLC30A3,NT5M,GDPD5,SLC17A7,KAT6A,NLRP3" Drug 5926_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "RALGAPA1,ASIC1,ADORA2A,ADRA1D,C1QTNF1,BIN1,CDC42BPA,APBA2,APC,CFLAR,CAPN3,CLGN,CHRNA4,TPP1,COL9A3,SNX29,FGFR1,GAD1,STON1,GPER1,ATXN2L,ELOVL5,MAP2,MID1,MMP16,ZNF862,NEK1,NPR2,PCDH9,PLEC,MAPK7,RELN,WDR25,RNASEL,EMID1,ZNF821,ASAP3,ST6GAL1,NLGN1,LIMCH1,SNCA,FAIM2,ATP10B,TAL1,OBSL1,HEY1,SLC30A3" Drug 4324_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ASPHD1,ACHE,AMPH,PKP4,PPP4R4,ADAM15,BAIAP3,CREM,PDE4DIP,C2CD2L,DTNA,DTNB,ECM2,LRRC17,FGF1,FGF12,FOXF2,OGA,TRAF3IP2,SOX21,DHX35,ITGA7,KCNB1,KCNJ5,MGAT3,MT1M,NTRK2,NTRK3,PFKFB4,CCDC40,RASGRF1,RGS4,GSTCD,CCDC102B,STUM,RASA3,SH3BP2,ZNF667,SP4,ZBTB43,CEP68,JMJD6,DMXL2,TIMP4,CBX5,NT5M,KCNAB1" Drug 7213_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "AP2A2,AK2,AMH,GAS7,MARK4,PTCH2,ATP1A3,ADAM23,CFLAR,CACNA1I,CACNA2D1,CBFA2T2,CBARP,TPP1,WHRN,RCHY1,SNPH,DAPK1,RASGRP2,IGSF6,AFF2,OGA,GFRA2,RUNDC3A,SPACA9,LIG4,MGAT3,AFDN,MMP16,NF1,PALM,RETREG1,SAMD9,WDR25,GAL3ST4,RGS12,TCP11L1,ZNF821,SH3GL3,FAM214B,ZNF415,CRTC1,TK2,NR2E1,FAM155A,EMSY,HPS4" Drug 2451_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "MTUS1,APBB2,RIPK1,MPDZ,ARHGEF7,CACNA2D1,HIP1R,SPAG9,LARGE1,CHN1,CNOT8,EPS15L1,SULT4A1,COL9A3,RIMS2,TBC1D5,MFAP3L,OPTN,MBNL2,FER,ANKFY1,NBEA,TRAF3IP2,GALC,POLL,ATXN2L,HSF2,KCNJ5,KPNA5,LSS,AFF1,NNAT,PLCD1,PTPRN2,GAL3ST4,MAP6D1,SCN8A,FNDC3A,SLC12A4,PEG10,SS18,NXT2,SEPT8,PHLDB1,RPGRIP1L,SZT2,ZNF24" Drug 6447_DN Metyrapone [54-36-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "BRAP,SEMA6A,APC,EPB41L5,CDC14B,ARNTL,STX16,RAB28,NRG2,ENTPD4,GREB1,TOM1,IRAK4,ENO2,ANKMY1,FGFR1,BAIAP2,TRMO,PRELID3A,MSL3,HSF2,MAP4,MAPT,ZNF862,SLC11A2,ZSCAN32,RIPOR1,RAP1GDS1,RGS12,NEK11,ZFP30,CXXC4,ERC1,TROVE2,CEP68,DIP2A,ARC,MCF2L,KIAA0930,HIRA,FAM155A,XRCC4,ZNF74,UPF3A,MAP3K12,HPS4,SMIM8" Drug 4419_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "SEMA6A,APBA2,APBB2,GAS7,NUMB,SLC2A11,FOXN3,LHX2,AKAP7,WHRN,CPS1,SEC14L5,RASSF2,SPOCK2,DMPK,HSD17B14,ERCC2,DLC1,FGF12,SRCAP,GFER,KCNN1,MAP4,KITLG,MID1,GIT1,ADAM22,LRP12,RGS3,ASAP3,FAM214B,PKNOX2,CCDC88A,SLC11A1,KDM4B,PDZD2,IQSEC2,CLSTN2,RGL1,WSCD1,DMXL2,ZEB1,DICER1,R3HDM1,PIK3R5,FLRT2,VIPR2" Drug 5760_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ADD2,EIF4G3,ST3GAL5,KRIT1,RAB28,HOMER3,ARMC8,AKAP5,CRMP1,PHF14,EDIL3,HEYL,PLXNC1,ING4,ZNF391,STAU2,SYT17,COPS8,FERMT2,JAK2,KCNJ5,MGAT3,LYRM9,NOVA1,OXTR,PDE4D,PTCH1,PTPRN2,RBBP6,RGS12,RNASEL,CSRNP3,STUM,SUPT20H,HSPA4L,FNDC3A,CCDC88A,PDZD2,SPTAN1,ARC,SYT1,COBL,MCF2L,RPGRIP1L,EPM2A,FAM13C,SENP7" Drug 7360_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ASIC1,AP2A2,ALCAM,APC,CDK13,CFAP410,CBFA2T2,SCARB1,HDAC4,GIT2,SPATA2,DTNA,EPB41L2,CDKL3,FGFR1,TRMO,TRAF3IP2,GLYR1,GRB10,IL6R,KCNH2,LMO2,MBD1,MPP2,NFYA,STRN3,RIPOR1,ZCWPW1,GSTCD,NEK11,FBXW7,EMID1,SEC14L1,ZFP30,SH3BP2,FRMPD1,PPP4R3A,CDK19,CLSTN2,ELOVL4,ARHGEF9,MCF2L,EXOC7,SZT2,TRIO,VAV1,KCNAB1" Drug 4256_DN Tocainide hydrochloride; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ASPHD1,AMPD3,PPFIA4,KSR1,BAIAP3,CRLF1,TPP1,HOMER3,AKAP7,RCHY1,CSF1,ARHGEF10,VCAN,CNTNAP2,ARHGAP24,SPOCK3,MTSS1L,AFF2,OGA,FYB1,SIGLEC8,ALDH1L1,RUNDC3A,LPAR4,GRM8,SOX21,HNMT,ITPKA,KCNJ5,KCNN1,LMO2,MAPT,AFDN,ADAM22,NDP,PALM,FA2H,PTPRB,ASAP3,KIF13A,TLR4,R3HDM1,SPHK2,REEP1,KCNAB1,PARP11,FAM13C" Drug 4724_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "RALGAPA1,ABHD6,ACTN1,AP2A2,NME5,ALCAM,AMPD3,SEMA7A,PLA2G4C,CDK13,CFLAR,CFAP410,HIP1R,CACNA2D2,ASIC3,TAOK2,STOML1,QKI,GREB1,PARD6A,EXOG,IRAK4,ING4,FGFR1,IQCG,OGA,GALC,TDRKH,GRB10,CACFD1,TJAP1,KCNH2,KCNN2,AFF1,TMEM231,RBBP6,GSTCD,TCP11L1,SMARCD3,LIMCH1,ZC3H13,PHLDB1,JMJD6,PLCB1,SLC19A3,PCDHA6,CHST8" Drug 4276_DN Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "AP2A2,CDK10,PPP4R4,RASL11B,KIF1A,SYNJ2,MYRF,BAIAP3,CFAP410,AKAP7,WHRN,SH2B1,CRMP1,CSNK1E,DZIP3,GIT2,SPOCK3,RGS17,HPCAL4,FLT1,CSPG5,INPP5K,SRCAP,POLL,FERMT2,ATXN2L,SHISAL1,INPP5B,MAP4,MAPT,MEIS1,MIA2,LYRM9,ZNF862,PALM,PLXNB1,ASAP3,ZNF667,ZHX3,IQSEC2,DNAH7,CABIN1,VGF,VIPR2,SEMA3B,MPPE1,SENP7" Drug 3390_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "AK2,LTBP4,BIN1,SEMA7A,APC,CFAP410,STOML1,PDE4DIP,PHF14,DCAF4,TOM1,NCALD,SCML2,FER,FGFR1,BAIAP2,PDLIM5,SRCAP,GLYR1,TDRKH,GSN,AGFG1,KCNH2,SMAD1,MMP16,ADAM22,PALM,NLE1,PLCD1,STRN3,LRP12,ELOVL2,SBF1,FUZ,FNDC3A,PPP4R3A,PKNOX2,BTBD7,SNCA,DIP2A,DICER1,AP4E1,TPM2,TRIO,ZNF24,REEP1,EPM2A" Drug 3834_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.64E-07 2.03E-02 3.18E-05 3.58E-04 47 196 "ADORA1,SEMA6A,KCNAB2,SEMA4G,PLA2G4C,LDLRAD4,SLC16A4,CDO1,NRXN3,ARHGEF6,CNTN1,WHRN,EGFR,ING4,PTK2B,AGAP2,PDLIM5,GAD1,DISC1,SRCAP,ADAM28,CSDC2,PRUNE2,GPER1,ATXN2L,TJAP1,KCNH2,KCNQ3,KHK,TM6SF1,AFF1,MMP17,NOVA1,NOVA2,TMOD2,CPEB3,ST6GAL1,RGL1,TBCEL,DMXL2,CUX2,TRIM2,PCDHA5,SLC35G2,TRIO,PDIA2,SLC30A3" Drug 4112_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.97E-07 2.18E-02 3.39E-05 3.82E-04 43 173 "ADRB2,NME5,MARK4,ST3GAL5,BAIAP3,USP2,CLGN,WHRN,AKAP12,PDE4DIP,ARMCX2,TSPAN5,FRY,OPTN,FAM13A,FYN,CYP46A1,STON1,MAP2,MEF2C,MXI1,NEK1,PCDH9,SERPINI1,GRAMD1C,PRPH,RADX,SH3GL3,ASAP3,WDR47,PKNOX2,CCDC88A,LIMCH1,SOX15,THSD1,ELOVL4,RGL1,STXBP1,HEY1,NPL,RUNDC3B,SLC30A3,SLC17A7" Drug 1050_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.97E-07 2.18E-02 3.39E-05 3.82E-04 43 173 "ARNTL,BMP7,ST3GAL5,RAB29,KYAT1,ARMCX2,TSPAN5,OPTN,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,FYN,RAB40B,STON1,RNFT2,PADI2,FAM69A,MXI1,NEK1,PCDH9,PMP22,PKIA,PRPH,SGK1,SH3BGR,SH3GL3,PPM1E,WDR47,ZBTB43,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,NDRG4,REEP1" Drug 5594_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.97E-07 2.18E-02 3.39E-05 3.82E-04 43 173 "ADRB2,NME5,APAF1,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,FAM13A,STX2,ACSL4,BAIAP2,HPCAL4,FYN,CYP46A1,RAB40B,STON1,MAP2,NEK1,PCDH9,ENPP2,TMOD2,SERPINI1,GRAMD1C,PRPH,RADX,SH3GL3,WDR47,PKNOX2,ARHGAP26,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SLC30A3,SLC17A7" Drug ctd:C487081 belinostat CTD 5.03E-07 2.20E-02 3.43E-05 3.86E-04 120 679 "RNF150,CEP126,PCDH10,AMPD3,EPB41L5,APOC1,SFMBT2,PPP4R4,ARRB1,ASGR1,BMPR1B,SYNJ2,JAZF1,RAB29,CA4,CALB1,RUNX1T1,DGKI,CDC25B,NOG,RCBTB2,SLIT2,LHX2,RAB33A,NGEF,C4orf33,CNTN1,HAPLN1,KIAA0040,ARHGEF4,ARHGAP24,DUSP9,EDN1,EDNRA,EDNRB,PLXNC1,EIF4G2,LRRC17,NCALD,CEP85L,PIPOX,EZH1,TAOK3,CHST15,SLC9B2,FLT1,EFCAB2,FUT9,GABRB3,GAD1,FREM1,MAP7D2,MCHR1,STMN2,FAM19A2,FAM222A,TOX2,NEGR1,IDH3A,IFI16,SHISAL1,IGF1,INPP1,LRRTM1,LIFR,LMO2,MAP6,SHC3,NEXMIF,BEX5,NDP,IDNK,NELL2,NPY,NTRK3,NUCB2,CNTN3,PCDH8,NLGN3,SERPINI1,SNX10,IRX1,ZFHX4-AS1,LRRN3,EPDR1,RELN,ELOVL2,STK32A,PTX3,PRIMA1,ROBO2,GLDN,HUNK,RTN1,SEMA6D,HKDC1,CNKSR2,LIMCH1,SNAP25,DOK5,KDM4C,PEG10,LMO3,SST,COBL,TACC1,ADGRL3,ZEB1,ZMAT3,GALNT17,SGK3,UGT8,RBFOX3,ZBTB38,ANKS1B,TUBA1A,SEMA3B,NAV3,NETO2,CPNE4" Drug ctd:D012643 Selenium CTD 5.24E-07 2.30E-02 3.45E-05 3.89E-04 245 1605 "DGCR6,ABR,ACHE,AS3MT,ACTN1,ADCY6,ADD1,ADORA2A,AP2A2,OSBPL1A,AK2,ALCAM,LTBP4,AMPD3,BIN1,CDC42BPA,APC,CDC14B,CDK10,PRX,ARHGDIA,SLC4A4,ADGRB1,BARD1,BID,CFLAR,SYNJ2,SCAPER,LDLRAD4,THSD7A,CAMK2B,HIP1R,RUNX1T1,NFS1,ZMYM4,LRRFIP1,SRSF11,CHN2,CHRNA4,CNOT8,SLIT2,CLCN3,TPP1,CLTB,CNN3,IQCK,FAM149A,RCHY1,CSF1,CSNK1E,CST3,KIAA0040,PPP6R2,TCAF1,ZNF337,TM9SF4,INTS1,DAPK3,DCTN1,HEPH,B3GAT3,FBXL5,RUSC2,GSDME,RHOBTB1,SACS,SEC16A,USP3,DMTF1,ECM2,FIS1,E2F6,EDNRA,EEF1D,OPTN,EGFR,AASS,EIF4G1,USPL1,ENO2,MFSD10,ERBB2,GMPR2,TUBA1B,TUBB3,SCML2,FCGRT,FDFT1,PRMT5,FECH,SEC24B,ATP5PD,SEC23B,FOXF2,SYNCRIP,FOXO3,FLT1,NOP56,FOLH1,ATP2C1,ERGIC3,RAPGEF6,ZNF274,INPP5K,ALDH1L1,MALT1,DHRS4,TCERG1,RNPS1,HPGDS,GLI2,POLL,ADAP1,GRIA2,GSN,GSTT2,PSIP1,FAM107A,MAP4K5,MAN1B1,HLF,SYNPO,HMGCR,HNMT,ICA1,IDH3B,IL6ST,KTN1,PAXBP1,MAP4,MBD1,MBNL1,MBP,CHST6,MMP16,PTOV1,THYN1,MX1,MYO6,NACA,HNRNPM,NEK1,NFE2L2,SLC11A2,OGG1,OPA1,PCDHGC3,PCSK5,PDPK1,OLA1,CCSER2,PKD1,PKM,PLEC,SMOX,RETREG2,EPB41L4B,PPP2R5E,PRKCB,MAPK3,MAPK9,PIGG,PTPRO,PTX3,TUG1,USP47,C1orf54,FAT4,ZCWPW1,RBBP6,KCTD17,SLC25A36,RNH1,ALG9,RPS6KA2,RPS20,RXRA,SAFB,SATB1,ATXN7,FERMT1,ASAP3,CHD9,FBXO11,FHOD3,SEC31A,EPN2,DHX30,SLC6A8,SLC12A2,SMARCA4,SMARCD3,RCOR3,TTC17,LIMCH1,SNAP25,USP33,UHRF1BP1L,SPP1,UNC5B,SPTAN1,TROVE2,ST5,SUPT5H,PRRC2C,DNAJC9,MMS19,PJA1,MLST8,MCF2L,FAM208A,TBL1X,ATMIN,SIN3B,DMXL2,ZEB1,TCF12,OBSL1,TNS2,CRTC1,DICER1,SIRT1,THRA,TIMP4,CBX5,R3HDM1,CABIN1,TPM2,WBP2,TRO,TSC2,TTC3,GORASP1,OSBP2,VGF,ZNF195,UPF3A,INTS3,EMSY,EVI5,SEMA3B,ITM2C,PDSS2,NLRP3,FXR1" Drug 4302_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.36E-07 2.35E-02 3.45E-05 3.89E-04 46 191 "ADRB2,ARNTL,MARK4,N4BP2L1,ADGRB2,ST3GAL5,BAIAP3,HIP1R,WHRN,CRY2,ABCG1,PDE4DIP,CNTNAP2,CTH,PLPPR4,MRNIP,TBC1D16,TAOK3,BAIAP2,FYN,CYP46A1,FAM69A,LSS,MAP2,GIT1,TAGLN3,SERPINI1,PPP2R2B,PRPH,RGS4,RPS6KA2,SH3GL3,DZIP1,DOP1A,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,COBL,SMG6,TIAM1,CABIN1,TRIM9,SLC17A7,DPF3" Drug 7417_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.36E-07 2.35E-02 3.45E-05 3.89E-04 46 191 "ADGRF5,APBB2,EPB41L5,ARNTL,ARRB1,MPDZ,CFLAR,ARHGEF7,SCAPER,MTMR3,USP2,MAGI1,FBXL5,DTNA,PHF20L1,EIF4G2,COQ7,MTSS1L,STX2,ANKMY1,SYT17,SRCAP,RUNDC3A,ZNF276,SPACA9,RNFT2,HMGCR,INPP5B,MBD1,AFDN,ADAM22,MYO7A,NF1,MBOAT7,RIPOR1,RGS12,KCTD17,SH3GL3,HKDC1,IQSEC2,KIAA0930,TRIM2,PCDHA5,ZNF189,MAP3K12,HPS4" Drug 5237_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.36E-07 2.35E-02 3.45E-05 3.89E-04 46 191 "SPARCL1,SEMA7A,GAS7,CDC14B,MARK4,ATP6V0A1,BMP7,GYG2,FOXN3,TAOK2,LHX2,WHRN,CRY2,FAM169A,RIMS2,DBN1,CDON,HSD17B14,RASGRP2,GAD1,PCDH17,GLYR1,ICA1,IL6R,MAP4,TM6SF1,ZNF862,PLCD1,MTRF1L,LRP12,PTCH1,FAM184A,RGS12,ZNF821,SH3BP2,PEX26,FAM214B,LIMCH1,ZSWIM8,RGL1,KIAA1107,WSCD1,TRPM2,HIRA,ITM2C,TIGD6" Drug 1665_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.36E-07 2.35E-02 3.45E-05 3.89E-04 46 191 "ASPHD1,PPFIA3,ALDH7A1,BMP7,RAB29,SYNGR3,ARHGEF2,MAGI1,ABCG1,PDE4DIP,LYPD1,SPOCK3,RCAN1,EGFR,MBNL2,EIF4G2,HSD17B14,ZNF589,FER,BAIAP2,FHL1,FYN,SYT17,STON1,RASSF8,MAPT,CNOT4,PDPK1,RETREG2,FA2H,PRPH,PTCH1,SUSD4,KCTD17,CCDC25,MAP6D1,CLIP1,ZNF821,ASAP3,LIMCH1,TRIM2,CRTC1,BEX4,VGF,REEP1,MAP3K12" Drug 2539_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.36E-07 2.35E-02 3.45E-05 3.89E-04 46 191 "C1QTNF1,C1QTNF3,EPB41L5,SLC4A4,NRP2,GYG2,BAIAP3,LDLRAD4,CD86,B4GALT6,STOML1,FAM149A,CDC42BPB,CREM,TMCC2,PLXNC1,ING4,ZNF44,SIGLEC8,NEU3,LYVE1,GNAL,RASSF8,ATXN2L,MEF2C,ADAM22,MYO6,NINJ2,PDE4B,CCSER2,SEPT4,POU6F1,MAPK10,ROBO1,EMID1,SCN2B,SH3BGR,SH3BP2,ASAP3,KANSL3,SPTAN1,TROVE2,SYT5,DNMBP,WNT7A,ZBTB38" Drug 2156_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "MTUS1,SEMA6A,ALK,CASK,SULT4A1,CNTFR,AKAP7,WHRN,CRMP1,ABCG1,SIPA1L1,PDE4DIP,PPP1R16B,RUBCN,DOCK4,ARHGAP32,C3orf18,EIF1,EPHB1,ZNF549,DCTN2,PRELID3A,TMEM8B,CSDC2,LILRA2,PADI2,KCND1,MAP4,MEF2C,MIA2,N6AMT1,ZNF862,PDE4B,PMP22,RIPOR1,RGS3,RGS4,ZC3H13,SPTAN1,SPTB,LHPP,CEP68,SYNE2,HIF3A,RUNDC3B,FLRT2,CLIP2" Drug 6686_DN Dichlorphenamide [120-97-8]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "RALGAPA1,KCNAB2,NRP2,ST3GAL5,CFAP410,KRIT1,FOXN3,TAOK2,PICK1,CPS1,PDE4DIP,ARHGEF4,PARD6A,SGSM2,CHRDL1,HSD17B14,COQ7,DENND4A,F8,GAD1,ICA1,SCIN,IL6ST,TM6SF1,PDE4B,RETREG1,GRAMD1C,PRPH,CNNM2,PTN,ZSCAN2,SH3TC2,KHDRBS2,MRPS18A,ZNF671,RPS6KA2,SUPT20H,UHRF1BP1L,UNC5B,DDN,PLCB1,SZT2,TMEM121,TK2,XRCC4,FIP1L1,PCBP4" Drug 4555_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "AMT,EPB41L5,APOC1,PPP4R4,NRP2,CFLAR,BMP7,ST3GAL5,MTMR3,SLC16A4,CBFA2T2,SCARB1,CSF1,ARHGEF10,IPCEF1,SV2B,DTNA,ING4,GAD1,RUNDC3A,GPER1,GRM8,BACH2,MAN2A2,AFF1,MMP16,NTRK2,PDE4D,ENPP2,POLG,RASGRF1,KHDRBS2,KLHL11,SCN8A,RASA3,FAM102A,SLC2A5,ZHX3,RBM26,LHPP,ARHGEF9,ADGRL3,TRIM2,GPR161,SSBP2,EVI5,KCNAB1" Drug 2860_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "RALGAPA1,NDRG2,ADORA2A,MTUS1,AMH,AMPD3,GAS7,ALDH7A1,CFLAR,CACNA1I,CALB2,ARHGEF2,FOXN3,TAOK2,SLIT2,ARHGEF6,CPS1,VCAN,MAML1,ZNF804A,OPTN,ING4,ERCC2,NCALD,FGFR1,FHL1,FAM49B,FYB1,GCNT2,STON1,GSN,ICA1,KCNN1,KHK,LAMA2,MAPT,TM6SF1,MITF,MSR1,NTRK2,CEP41,EPN2,SLC22A4,SNCA,ARHGAP26,DICER1,ST7" Drug 2263_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "AK2,ALCAM,TRMT9B,CDC42BPA,GAS7,CACNA1I,BAIAP3,CDH2,KCNAB3,CPS1,CSF1R,GREB1,ARHGAP24,DAPK1,DTNB,MBNL2,SRPK3,VPS13B,ABCA8,DLC1,FGFR1,OGA,PCLO,GRIN2C,GUCY1A1,KIF5A,NNAT,NTRK2,MTRF1L,PDZRN4,SAMD9,RGS12,KLHL11,SATB1,SH3BP2,NLGN1,PKNOX2,SLC14A1,COA1,DOK5,HECW1,JMJD6,WSCD1,CHST5,FLRT2,ADAMTS9,SMIM8" Drug 4465_UP "estradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADRA1D,APAF1,KCNAB2,PTBP2,RUNX1T1,CBS,RAB33A,RAB26,AKAP5,PDE4DIP,APPL1,USP6NL,DBT,SPOCK3,CHRDL1,EXOG,EGFR,ETV1,TMEM8B,PCDH17,LYVE1,GLI2,CACFD1,NXPH3,IFI16,ITGA7,LAMA2,NPTX2,PALM,CDK18,PDE4B,PFKFB2,NLE1,LRP12,PTCH1,ELOVL2,PTPRN2,FAT4,SLC25A36,SH3BP2,HECW1,MCF2L,SZT2,DOCK9,CDK20,HIRA,FLRT2" Drug 2766_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADORA1,ADORA2A,AP2A2,OSBPL1A,LTBP4,ALK,APBA2,APLP1,PPFIA3,CAMK2G,ARHGAP33,HOMER3,SH2B1,CRY2,INTS1,DMPK,SLC12A6,RASGRP2,F5,CAMKK2,PRRC2B,GPER1,DHX35,ITGA7,MAP4,CDK18,PLTP,MBOAT7,RIPOR1,KCTD17,EMID1,FAM102A,FAM214B,KDM4B,TEX2,ARHGAP26,CAMTA2,SAMSN1,ARC,EXOC7,IQCE,HIF3A,PIK3R5,HIRA,WIPF1,ZNF74,VPS35L" Drug 6015_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "APBA2,APBB2,APOC1,SEMA4G,MARK4,CFLAR,GYG2,CACNA1I,CFAP410,HAP1,KCNAB3,TAOK2,CRMP1,CRY2,PDE4DIP,HIPK3,TNK2,COQ7,FHL1,OGA,SRCAP,GSN,GSTM5,ATXN2L,IRF8,AFDN,NF1,CLDN11,PFKFB2,DUSP26,PLCB2,LRP12,GRAMD1C,PTPRN2,KIF16B,ST6GAL1,EPN2,SLC6A11,DOK5,UHRF1BP1L,KIAA0930,AP4E1,HEY1,METTL3,TRPM2,WIPF1,LAMP5" Drug 6145_DN Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ASIC1,MTUS1,PKP4,APAF1,NUMB,SLC4A4,SYNJ1,PLAA,IQCK,C2CD2,PLXNC1,IRAK4,TNK2,CD320,PDLIM5,FYB1,SEPT9,INPP5K,TXNL4A,RAB40B,GPD2,IPO5,MIA2,ZNF862,PLCB2,SMIM7,PMP22,LRP12,MINDY2,PPP3CC,TMEM231,CEP97,SLC2A5,FAM214B,KBTBD4,ZNF667,SNCA,KDM4C,ARHGAP26,SS18,SIN3B,SLC44A1,TNS1,ZKSCAN5,XRCC4,ZBTB38,KCNAB1" Drug 5701_UP Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "APAF1,APC,DDO,APOC1,SEMA4G,ALDH7A1,N4BP2L1,CACNA1I,NRXN3,IPCEF1,CNTNAP2,RASSF2,HS3ST2,EDNRA,NRN1,ZNF589,FGFR1,AFF2,FYB1,GAD1,GUCY1A1,KCNJ5,ADAM11,MYO7A,PCBP3,P2RX7,PALM,NECAB2,PPP1R1A,LRRN3,PTCH1,PTX3,CEP97,TCP11L1,SH3BP2,FAM214B,SLC11A1,FAIM2,PEG10,ATP10B,TTBK2,SYN2,TRIM2,PCDHGB6,SYNE1,SLC35G2,DICER1" Drug 1503_UP Metronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "SYN3,C1QTNF1,SPARCL1,LTBP4,BIN1,PPFIA3,ARHGDIG,SCAPER,LDLRAD4,NFS1,CCNT1,SEPT7,CRLF1,SOCS6,SNCAIP,C2CD2L,DTNA,ING4,NCALD,RRAGB,F5,IQCG,ZNF44,AHDC1,GLYR1,MBD1,NACA,RETREG1,PRODH,PTCH1,KCNIP1,ASAP3,ANKRD6,PEX26,PPP4R3A,OGDHL,MAPKBP1,FNBP1,ELOVL4,ARHGEF9,MCF2L,TMEM121,CHST8,TK2,TPM1,MAP3K12,HPS4" Drug 6994_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ASPHD1,APLP1,MARCH3,ALDH7A1,CFLAR,SCAPER,MTMR3,KYAT1,B4GALT6,FAM189A2,CNTN1,MED12,SLC12A6,EGR3,TNK2,CDKL3,RRAGB,FECH,FER,FYB1,MSL3,GRM8,HNMT,ITPKB,IPO5,MAPT,MGAT3,MPP2,SMOX,NECAB2,MAPK7,MAPK10,SAMD9,ZSCAN32,CCDC40,GTDC1,SYBU,CCDC88A,ZKSCAN3,SPTAN1,ELOVL4,PLCB1,ZKSCAN5,SEMA3B,KCNAB1,FAM13C,RNF170" Drug 7447_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "NDRG2,SEMA7A,SLC4A4,BMP7,CFAP410,CAMK2G,CBFA2T2,ARHGAP33,CNTNAP2,FAM169A,HS3ST2,DPP6,ING4,ACSL4,OLFM1,FGF12,BAIAP2,B4GALNT1,TXNL4A,ADAMTS13,KCNJ5,LMO2,MAP4,MIA2,ZNF862,ENPP2,RETREG1,PLCD1,PLXNB1,PPP2R2B,PRKAR1B,RIPOR1,GAL3ST4,KCTD17,RNASEL,GSTCD,RPS6KA2,SH3BP2,CCDC88A,SLC11A1,LIMCH1,SPTAN1,THSD1,ELOVL4,MCF2L,CDK20,KCNK12" Drug 4980_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "PPFIA3,SYNJ2,MTMR2,CFAP410,CLGN,FOXN3,SLIT2,CNTNAP2,ARHGEF4,ZNF804A,DTNA,HIPK3,CELSR3,MBNL2,ING4,EZH1,PRELID3A,SYT17,DISC1,MSL3,POLL,GRIK5,ELOVL5,MBD1,KITLG,NEK1,CNOT4,PLCD1,SLC25A23,LRP12,GRAMD1C,SBF1,FNDC3A,SYBU,PREX2,PEX26,EPN2,RBM34,KDM4B,TROVE2,ASTN2,EXOC7,TMEM121,VLDLR,EVI5,ST7,UBE3B" Drug 7374_DN Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "BIN1,CDC42BPA,APC,MYRF,HOMER3,ARHGEF6,IQCK,CSNK1E,OSBPL3,PDE4DIP,CNTNAP2,KIAA0753,EDNRA,FEM1B,COQ7,ZNF589,FER,TMEM8B,PRRC2B,GUCY1B1,RASSF8,MAN1B1,SYNPO,KHK,MAP4,MAPT,MBD1,GIT1,MT1M,PIK3R1,PLCD1,POLG,FSD1,RGS4,ZNF671,SMARCC2,LIMCH1,KDM4C,ELOVL4,TIAM1,PARD3,UGT8,WNT7A,XRCC4,ZBTB14,MAP3K12,NT5M" Drug 4160_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ASIC1,ADORA1,SEMA7A,CDK10,PDE8B,RASL11B,CFAP410,KYAT1,RCBTB2,ASIC3,SLIT2,HOMER3,SH2B1,CRY2,SNCAIP,RIMS2,DCAF8,MAML1,TMCC2,HIPK3,EZH1,BAIAP2,FHL1,KHDRBS3,GNG4,PRRC2B,RNFT2,INPP5B,KCNH2,SMAD1,MAP4,MPP2,SETD4,NLE1,PLCD1,LRP12,GRAMD1C,TRIM68,SH3BP2,SLC9A5,SNCA,CDK19,ZBTB43,TROVE2,PLCB1,RUNDC3B,TRPM2" Drug 3311_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "AMPD3,APC,SLC4A4,CFLAR,CACNA1I,CFAP410,CAMK2B,CBFA2T2,RCBTB2,FOXN3,TPP1,QKI,SULT4A1,HIPK3,EGFR,ETV1,ZNF589,FGF13,POLL,GNG4,GRM8,ATXN2L,IL6ST,KCNN1,ADAM22,NEFM,CNOT4,MTRF1L,NECAB2,PPARA,GRAMD1C,SAMD9,KCTD17,GSTCD,SLC9A5,FAIM2,SOX3,PHLDB1,ARC,PCDHA5,ZNF34,THRA,UGT8,XRCC4,NT5M,EVI5,SENP7" Drug 6383_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "NDRG2,SYT13,APC,SEMA4G,NRP2,BAIAP3,FOXN3,TAOK2,CRMP1,CSF1,FAM131B,RIPOR2,MFAP3L,C2CD2L,KLHL3,EDNRA,FCF1,MBNL2,HSD17B14,IGSF6,PTK2B,FGF1,FYN,DISC1,POLL,GRIK5,TJAP1,L1CAM,LIFR,AFDN,MMP16,NNAT,CNOT4,PAX6,PFKFB2,GRAMD1C,PTPRD,ZFHX4,KCNIP1,SATB1,TROVE2,ARC,SMG6,TRO,WIPF1,LAT2,SLC30A3" Drug 4742_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "RALGAPA1,ASIC1,AP2A2,ALCAM,AMPD3,OGT,APBB2,BCAS1,SLC16A4,TPP1,HAPLN1,AATK,CSF1,ARHGEF10,SPOCK3,HIPK3,EGFR,APC2,FUT9,OGA,MALT1,GRM2,GSN,TJAP1,PCBP3,PFKFB2,PPARA,PPP5C,RELN,ELOVL2,ZSCAN32,C1orf54,ZNF493,TRIM68,EMID1,ZNF415,KDM4B,RBM26,SPART,TBCEL,ZEB1,SZT2,DOCK9,TNS1,LAT2,ITM2C,PHTF2" Drug 2768_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "AK2,C1QTNF3,OGT,CDC42BPA,MPDZ,MAGI1,CNOT8,TAOK2,CLCN3,SOCS5,PPP6R2,MAML1,HIPK3,ING4,RRAGB,KAT8,ZNF589,FECH,FGFR1,INPP5K,MSL3,KCNH2,LSS,MMP16,NFYA,CNOT4,OPA1,PCDH9,PLEC,PMP22,ZSCAN32,RIPOR1,EPN2,ZKSCAN3,SPTAN1,ITPRID2,PLCB1,PCDHA6,AP4E1,ZKSCAN5,PLPPR2,VGF,CLDND1,ZNF24,REEP1,UPF3A,UBE3B" Drug 422_UP thioridazine hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "GAS7,APOC1,WASF1,CA12,HAP1,CAMK2G,SLC25A14,SEPT7,CNOT8,TAOK2,CNTN1,CRMP1,PDE4DIP,GPRASP1,SPOCK2,DYNC1I1,EGR3,ETV1,EXTL2,FGFR1,PDLIM5,ALDH1L1,ZNF638,GNAO1,AGBL5,HSF2,IL6ST,NTRK3,SETD4,SNX10,RETREG2,RNASE1,RIC8B,SLC8A1,ELMO2,CDK5RAP2,HECW1,ZC3H13,POGZ,STX1A,PLCB1,TBL1X,OBSL1,TK2,VAV1,CIAPIN1,MPPE1" Drug 6211_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ASPHD1,ABHD6,AP2A2,AMPD3,SLC4A4,ALDH7A1,ARHGEF2,CRLF1,PLAA,CRY2,NCOR1,DZIP3,DAPK1,GIT2,SPATA2,RCAN1,VPS26C,FGFR1,PDLIM5,OGA,TRAF3IP2,GAD1,HNMT,DHX35,INPP5B,MPP2,NF1,NFYA,RETREG1,STRN3,PPP5C,PRKAR1B,PRPH,VPS13C,ZDHHC14,ZFP30,SYBU,BTBD7,SLC22A4,SPTAN1,ZBTB43,TTBK2,STX1A,CABIN1,SEMA3B,EPM2A,ST7" Drug 6674_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ACHE,ADGRF5,AMT,EPB41L5,BCAS1,N4BP2L1,AZGP1,CALB2,SCARB1,SULT4A1,SUSD5,PDE4DIP,CNTNAP2,SPOCK2,BRINP1,EDN1,ING4,F5,AGAP2,CSDC2,RUNDC3A,POLL,KCNB1,KCNN1,AFDN,NCAM2,NF1,NOVA2,NRCAM,NTRK2,PFKFB2,PPP2R2B,LRRN3,PRPH,DCHS2,CCDC40,GAL3ST4,SH3BP2,FRMPD1,ZNF334,HECW1,PHLDB1,ADGRL3,SMG6,PHF24,RIMBP2,NT5M" Drug 2357_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "NDRG2,ADRA1D,AP2A2,BIN1,AMT,SHROOM2,KIF1A,ADAM23,HIP1R,LARGE1,STOML1,NRG2,SH2B1,VCAN,BRINP1,SPOCK3,DRP2,EDN3,AFF2,NSG1,SEPT9,GFER,POLL,LILRA2,TJAP1,MYCN,PCDHGC3,PCSK5,LRP12,TMEM104,FAM184A,RGS4,SEC14L1,MRAS,FRMPD1,SLC11A1,ZBTB43,ZC4H2,RGL1,RPGRIP1L,PHF24,TNS2,CRTC1,PIK3R5,FLRT2,XRCC4,HPS4" Drug 6605_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "LTBP4,ALK,ANK2,GAS7,DDO,BACH1,CAMK2B,CAPN3,ARHGEF2,SEPT7,CRLF1,RAB33A,ARHGEF10,VCAN,PDE4DIP,BRINP1,MFAP3L,CHRDL1,EDNRA,PIPOX,DLC1,GATM,RUNDC3A,PRUNE2,INPP5B,AFF1,NF1,NTRK3,PCDH9,PLXNB1,PPARA,WDR25,ZSCAN2,SCN2B,MRAS,SLC8A1,SPTB,DDN,PHLDB1,PLCB1,SYP,TACR1,MCF2L,THRA,UGT8,LAMP5,SLC17A7" Drug 5088_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ACHE,ADORA1,BBOX1,TRMT9B,APLP1,ARHGDIG,DNAH17,SLC4A4,N4BP2L1,RGS11,HAP1,ENTPD2,DLGAP1,FOXN3,PICK1,WHRN,CSF1,RGS6,MFAP3L,DRP2,EDNRA,SRPK3,PIPOX,SCARA3,AGAP2,FYB1,SIGLEC8,GLI2,ICA1,KCNF1,KIT,MBNL1,AFF1,ZNF862,NF1,MASP1,SNRK,PTH1R,SEMA6D,SLA,SLC4A3,KDM4B,KDM4C,TAL1,KIAA1107,SZT2,TK2" Drug 6059_UP Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "SYT13,BIN1,CDC42BPA,GAS7,ARHGDIG,ALDH7A1,SCAPER,RAB33A,VCAN,CNTNAP2,SPOCK2,BRINP1,RUSC2,SPOCK3,HS3ST2,HSD17B14,ST3GAL6,FGFR1,GFER,GSN,ICA1,SHISAL1,TJAP1,ITPKB,KCNJ5,TM6SF1,NPY,SLC11A2,PCSK5,PFKFB4,POU6F1,LRRN3,PRKCB,PTPRO,ZSCAN2,CARF,S100B,CPEB3,PEX26,ARHGAP26,ATP10B,PCDHGA10,R3HDM1,TRO,FLRT2,SLC30A3,JPH3" Drug 5069_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "PRX,ATP1A3,ADGRB2,RGS9,BAIAP3,LDLRAD4,CFAP410,HAP1,RUNX1T1,CD86,CBARP,CHN2,WHRN,CSF1,BRINP1,DTNB,AASS,MTSS1L,FGFR1,AGAP2,FYB1,LYVE1,TOX3,ATXN2L,IGF1,KCNH2,KCNJ5,PACRG,AFDN,NNAT,PDE4B,RETREG1,GRAMD1C,PTPRH,PID1,RASGRF1,KCTD17,FRMPD1,KDM4B,PHLDB1,SYP,TBCEL,CHST5,VGF,LAT2,ZNF74,SEMA3B" Drug 7472_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ABHD6,ALCAM,AMH,BIN1,CFLAR,KSR1,SYNJ2,CACNA2D1,CALB2,FOXN3,LHX2,CNTFR,TBC1D5,SPOCK2,JAKMIP2,DMPK,SLC12A6,PIPOX,TBC1D16,FHL1,OGA,RAB30,GRM2,RNFT2,RASSF8,INPP5B,ITPKB,MIA2,NNAT,PLCD1,PLXNB1,PPP2R2B,PPP5C,PTN,ZDHHC14,TCP11L1,RPS20,ASAP3,SMARCD3,SNCA,DOK5,STXBP1,COBL,KAT6B,ZNF189,MAP3K12,MARCH8" Drug 7149_UP Aconitine [302-27-2]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "SHROOM2,SOCS6,HOMER3,ARMC8,ARHGEF10,PDE4DIP,HDAC9,ARMCX2,LYPD1,EXOG,MAMLD1,MBNL2,AASS,ETV1,ANKMY1,FGF1,FGF13,BAIAP2,TRMO,OGA,GAD1,SEPT9,RASSF8,MAPT,MATN3,MMP16,NF1,PLCD1,STRN3,PPARA,PRPH,SAMD9,ZSCAN32,PTPRE,GTDC1,MRPS18A,ST6GAL1,FAM214B,KDM4D,NXT2,ELOVL4,VPS13A,DNAH7,TRIO,EIF4ENIF1,EMSY,RNF170" Drug 2252_UP Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADGRF5,APC,CDK10,MARK4,CBFA2T2,SCARB1,TPP1,HOMER3,RCHY1,CSF1R,MBNL2,ING4,EPB41,MTSS1L,EPHB1,REEP2,FGF1,FGFR3,NSG1,OGA,GRM8,ATXN2L,TJAP1,KPNA5,MID1,PALM,PDE1C,GPR85,SAMD9,RGS12,TCP11L1,ASAP3,FNDC3A,ZNF334,HECW1,SPTB,THSD1,PHLDB1,ARHGEF9,EXOC7,TCF4,OBSL1,RIMBP2,FLRT2,CLDND1,ZNF45,PHTF2" Drug 3365_UP Ioversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "NDRG2,ADORA1,ADORA2A,AP2A2,C1QTNF1,TRMT9B,APAF1,APBA2,KCNAB2,APC,MTMR3,LDLRAD4,CFAP410,HIP1R,CBFA2T2,CDO1,VCAN,RASSF2,INTS1,HIPK3,EGFR,TNK2,F5,PTK2B,GCNT2,GPER1,GUCY1B1,VSIG4,INPP1,KIF5A,MEF2C,ZNF862,NELL2,NNAT,NOVA2,PPP5C,PTCH1,ZMAT4,DOK5,LMO3,SYN2,ADGRL3,TRPM2,LAT2,SLC30A3,KCNAB1,SENP7" Drug 1508_UP Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "APBA2,APLP1,MARK4,SLC2A11,MPDZ,SYNJ1,SCAPER,KRIT1,SOCS6,CNTFR,AKAP12,NCOR1,VPS13B,MTSS1L,FHL1,PDLIM5,POLL,TJAP1,IL6ST,JAK2,MEIS2,ADAM22,MSR1,ZNF862,CDK18,RETREG1,PPARA,PPP5C,MAPK7,PRPH,VPS13C,CEP97,REV3L,RASA3,SLC22A4,CDK19,SPART,ANKRD12,KIAA1107,DMXL2,CRTC1,KAT6B,CDK20,RUNDC3B,FLRT2,DNALI1,MPPE1" Drug 3524_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADORA1,ADGRF5,PPFIA4,APLP1,FAM131A,LDLRAD4,CACNB4,PLEKHB1,ENTPD4,NCOR2,CSF1R,ZNF804A,C2CD2L,PLXNC1,TENM1,ING4,TNK2,RASGRP2,CORO2B,ZNF589,FYB1,FYN,ALDH1L1,RUNDC3A,GLYR1,AP4S1,MN1,ZNF862,MYT1,CDK18,MAPK7,SYBU,SLA,PKNOX2,SLC11A1,CXXC4,SMARCD3,LIMCH1,ARHGAP26,DOCK9,OSBP2,LMF1,WIPF1,DNALI1,SLC17A7,KCNAB1,EPM2A" Drug 6669_DN Benzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "AMPD3,APAF1,APC,ADAM23,NRP2,CFLAR,SCAPER,CACNA1A,FOXN3,CHN2,B4GALT6,ARMC8,WHRN,SPOCK3,EXOG,EDNRA,MBNL2,TENM1,GPR37,GRM8,MMP16,MX1,LYRM9,PIK3R1,LRP12,PTPRH,ZCWPW1,NUDT11,NEK11,RPS6KA2,RXRA,ST6GAL1,DZIP1,TMCC1,SPTAN1,CDK19,TROVE2,THSD1,CEP68,KIAA1107,TBCEL,TCF4,DNAH7,TK2,TSC1,LAT2,NAV3" Drug 3639_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADORA1,SEMA6A,MARK4,CFAP410,KALRN,CAMK2B,CAMK2G,USP2,CDH2,CPS1,CRMP1,NCOR2,AATK,SPOCK2,EDN1,CAMKK2,GABRG2,ADAM28,GNAO1,SYNPO,TJAP1,INPP5B,KCNH2,KIF5A,ADAM22,NELL2,NF1,NFYA,PNMA3,C19orf57,PTH1R,RGS12,SH3GL3,SLA,KDM4D,TSNAXIP1,HECW1,IQSEC2,ZBTB43,HIF3A,TRO,UBE3A,VIPR2,LAT2,KCNK12,NT5M,SLC17A7" Drug 3555_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ADORA1,KIAA1324,APBA2,BCAS1,ATP1A3,ALDH7A1,CFAP410,RCBTB2,SLIT2,MYRIP,CSF1R,DCAF4,RIPOR2,RASSF2,SPOCK3,TMCC2,DNAH9,ERCC2,DLC1,FYB1,FYN,DISC1,GATM,ALDH1L1,GDF9,GPR162,CYP46A1,GRM2,ATXN2L,ITPKA,KCNB1,PACRG,SMAD1,MX1,PALM,RASGRF1,RGS4,RGS12,RPS6KA2,MRAS,SH3BP2,COA1,TNS2,GPR161,TRO,WIPF1,PLSCR4" Drug 7354_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "TRMT9B,APLP1,CDK13,SCAPER,CA4,THSD7A,SOCS6,NCOR2,MFAP3L,EIF5,VPS13B,RASGRP2,CDKL3,ST3GAL6,SIGLEC8,POLL,LPAR4,CNTRL,GRIK5,GRM8,ATXN2L,ELOVL5,IL6ST,KCNN1,MID1,MYT1,NF1,NOVA2,NPTX1,PDE4B,MTRF1L,SEPT4,SAMD9,CEP97,KHDRBS2,ZDHHC14,RGS12,RBM34,ZHX3,SPTAN1,TROVE2,ST5,TTBK2,RUNDC3B,WIPF1,KCNK12,XRCC4" Drug 4097_UP Gelsemine [509-15-9]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "NDRG2,PKP4,APC,SLC2A11,BMP7,MTMR3,CFAP410,HAP1,CAMK2B,LRRFIP1,TAOK2,AKAP6,SUSD5,ARHGEF4,SEC14L5,SPOCK2,C2CD2L,DTNA,EDN3,SEMA3D,RASGRP2,AGAP2,GABRB3,DISC1,NEU3,LYVE1,GNAL,GPD1,IGF1,ADAM22,NTRK2,ENPP2,CNNM2,MARCH1,CCDC40,KLHL11,PNMA8A,SEMA6D,ASAP3,PKNOX2,SNCA,RBM26,NFASC,TACR1,RIMBP2,TUBB1,KCNAB1" Drug 4767_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.43E-07 2.38E-02 3.45E-05 3.89E-04 47 197 "ASPHD1,NDRG3,PLA2G4C,CFLAR,CA4,CAMK2B,ARHGAP33,FOXN3,PLEKHB1,WHRN,CSF1R,ARHGEF4,RIMS2,MFAP3L,SLC12A6,OPTN,DENND4A,FAM198B,ST3GAL6,AFF2,ERAP1,SEPT9,RASSF8,ATXN2L,HNMT,KCNF1,NNAT,NPTX1,STRN3,MAPK7,ZFHX4,SBF1,SLC6A8,RBM34,ZC3H13,STX1A,PLCB1,SYNE1,DOCK9,CRTC1,DICER1,PARD3,TRIO,LMF1,EMSY,EVI5,EPM2A" Drug CID000000806 "D-myo-inositol-1,4,5-triphosphate" Stitch 5.80E-07 2.54E-02 3.68E-05 4.15E-04 104 569 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1B,AGT,ANK2,ARRB1,ATP1A3,SLC4A4,ATP2A2,ATP2B2,BTK,CACNA1I,CACNA1G,CA8,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,HAP1,CAMK2B,CCK,KRIT1,CD38,DGKI,LRBA,CACNA2D2,CHGB,MYL6B,HOMER3,CABP1,PLCXD3,DGKB,DGKG,IP6K1,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,EGFR,RASA4,EIF4G2,ERBB4,MRVI1,ST3GAL6,PPP1R1B,FGF1,IP6K2,ATP2C1,FYN,IP6K3,MTHFD2,INPP5K,GPR75,ADAP1,PLCD4,GRM2,GRM8,ACOT7,MYLK2,INPP1,ITPKA,ITPKB,MATK,P2RY13,OCRL,OXTR,P2RY1,PIK3C2A,PKD1,PLCB2,PLCD1,PLCL1,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,QDPR,RGS3,RGS4,GSTCD,RYR3,MAPK12,RASA3,FNDC3A,SLA,SPTB,PLCB1,TACR1,TPCN2,ACTR6,CABIN1,TRO,VIPR2,PLD4" Drug ctd:C008493 methylselenic acid CTD 5.86E-07 2.57E-02 3.72E-05 4.19E-04 81 413 "AMT,ANK2,CDC14B,CDK10,NCOA1,ATP2A2,BACH1,CFLAR,WASF1,CALM1,CAMK2G,CAST,CCK,ARHGEF2,RAB28,QKI,MYRIP,AKAP12,NCOR1,NCOR2,HEPH,DYNC1I1,DPYSL2,DTNA,ECM2,E2F5,EDNRA,EDNRB,OPTN,MBNL2,EIF4G2,ENO2,EPB41L2,STX2,DLC1,FOXO3,FLNC,FYN,ZNF274,HPGDS,FERMT2,GPR37,GSN,FAM107A,GUCY1A1,IFI16,IGF1,KCNH2,MAPT,MEF2C,MITF,ADAM22,MXI1,NME4,CDK18,PPM1B,PRKCB,MAPK3,MAPK9,HSPA4L,SGK1,SH3BGR,SLC14A1,SMARCA4,SMARCD3,SNAP25,FNBP1,SPTAN1,RGL1,STX1A,ADGRL3,TBL1X,ITGB3BP,GPR161,TPM1,SSBP2,WNT7A,ZNF24,REEP1,KCNAB1,ST7" Drug 6051_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.18E-07 2.71E-02 3.76E-05 4.24E-04 45 186 "ASIC1,ALCAM,KIF1A,GYG2,CA12,KYAT1,PLEKHB1,LHX2,RAB26,SH2B1,RASSF2,PARD6A,DPYSL2,STX2,ARMCX1,TBC1D16,ZNF589,IQCG,SYT17,SESN1,RAB40B,GNG4,GRIK5,MAPT,MPP2,SLC25A23,MBOAT7,PKIA,PRKAR1B,RET,RNASEL,SGK1,FAM102A,FAM214B,TMCC1,SPTAN1,ARHGEF9,VPS13A,ASTN2,TNS2,TMEM121,ZMAT3,CABIN1,REEP1,MPPE1" Drug 7382_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.28E-07 2.75E-02 3.76E-05 4.24E-04 46 192 "AMT,CDC42BPA,GAS7,SHROOM2,PDE8B,KIF1A,NRP2,LDLRAD4,AP4M1,TAOK2,PLAA,PDE4DIP,SNPH,DAPK3,MFAP3L,RUSC2,FCF1,COQ7,DENND4A,ETV1,FER,FGFR3,AFF2,GCNT2,CYP46A1,ICA1,MT1M,TAGLN3,MX1,PPARA,SAMD9,WDR25,PTPRE,PTPRH,SH3TC2,ZCWPW1,MAPK12,FUZ,ANKRD6,SLC4A3,SPTAN1,POGZ,PHLDB1,KLHL4,REEP1,KCNAB1" Drug 4144_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.28E-07 2.75E-02 3.76E-05 4.24E-04 46 192 "NDRG2,ADORA1,APLP1,FAM131A,PPFIA3,ALDH7A1,SYNJ1,CBFA2T2,ARHGEF2,SEPT7,ASIC3,LHX2,CSF1R,RIMS2,GPRASP1,RCAN1,EDNRA,HIPK3,ING4,VPS13B,FHL1,KHDRBS3,SEPT9,GPER1,ELOVL5,TJAP1,KCNF1,KCNN1,SMAD1,KITLG,NF1,PLCD1,TCP11L1,FNDC3A,SLC9A5,DOK5,SS18,PLCB1,EXOC7,ZEB1,PARD3,CABIN1,TRPM2,UCHL1,EPM2A,SENP7" Drug 6037_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ALK,TRMT9B,AMPD3,ANK2,SLC4A4,ALDH7A1,AZGP1,GYG2,CDH2,CLGN,STOML1,SULT4A1,WHRN,SNCAIP,CNTNAP2,RIMS2,CYBB,ZMYND10,ZNF589,ADAM28,GFER,RUNDC3A,GNAO1,PRUNE2,FAM107A,NXPH3,KIT,KITLG,AFDN,ADAM22,NOVA1,PALM,RETREG1,LRP12,LRRN3,KHDRBS2,RGS12,CARF,SMARCD3,SPTB,SYP,WSCD1,ZEB1,DOCK9,TPM1,NT5M,ADAMTS9" Drug 6515_DN Trapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ALCAM,AMH,CDC42BPA,APLP1,FAM131A,BCAS1,PDE8B,DNAH17,MARK4,ALDH7A1,KIF1A,CFLAR,GYG2,AATK,FAM169A,SEC14L5,DOCK4,DAPK3,DBT,C2CD2L,SUGP2,PLXNC1,STX2,ERBB2,BAIAP2,GAD1,GPD2,GPR37,GRIK5,ELOVL5,KCNH2,MAP4,ZNF862,NPTX1,CEP97,FUZ,NLGN1,ZC3H13,NSFL1C,EXOC7,CRTC1,TK2,HIRA,PLPPR2,VGF,ZBTB14,GDPD5" Drug 6139_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "C1QTNF1,BEGAIN,BIN1,CDC42BPA,ANK2,APBB2,CDC14B,KIF1A,SYNJ2,LARGE1,MAGI1,CHGB,CHN2,LHX2,PDE4DIP,DCAF4,SEC14L5,PLPPR4,FAM13A,PLEKHA1,CORO2B,BAIAP2,CAMKK2,KHDRBS3,HPGDS,GLYR1,GPD2,ICA1,MMP16,P2RY1,PDE4D,NECAB2,CARF,KCNIP1,FERMT1,EPN2,SNAP25,TMCC1,SOX15,HECW1,PEG10,ARHGAP26,CLSTN2,WSCD1,DOCK9,PARD3,OSBP2" Drug 6522_UP Azapropazone [13539-59-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ARRB2,CA4,CALB2,USP2,SLC16A4,AKAP7,AKAP6,WHRN,CNTNAP2,GREB1,RCAN1,DTNA,EDNRA,ST3GAL6,FGF13,AGAP2,OGA,ZNF44,ERAP1,GFER,GUCY1B1,SLC2A6,AFDN,NEFH,RETREG1,NLE1,PLCD1,NECAB2,PPP5C,ZMAT4,RGS3,NUDT11,RPS6KA2,FUZ,SLC11A1,ARHGAP26,PHLDB1,JMJD6,PLCB1,IQCE,SMG6,OBSL1,CRTC1,SLC44A1,R3HDM1,SLC30A3,JPH3" Drug 3329_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "NDRG2,NME5,AMH,AMPD3,CDC42BPA,GAS7,CDC14B,MARK4,N4BP2L1,CFAP410,PICK1,AKAP7,NECTIN3,SNCAIP,RIMS2,GSDME,CNNM1,C3orf18,ERCC2,PIPOX,OLFM1,FGF13,DCTN2,EFCAB2,GAD1,ADAMTS13,GSTM5,HLF,IL6R,KCNJ5,MAPT,MEF2C,AFDN,MMP17,NF1,PDE4D,PFKFB2,KLHDC8A,EMID1,PREX2,FAM214B,KDM4B,ZNF423,ATP10B,JMJD6,TBCEL,GPR161" Drug 6165_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,TRMT9B,SEMA7A,APBB2,PDE8B,HAP1,CLGN,CREM,AATK,CSF1,ARHGEF10,CSNK1E,RIPOR2,DGKG,MFAP3L,TMCC2,OPTN,F5,TBC1D16,BAIAP2,IQCG,GPR162,MSL3,PCLO,GUCY1A1,KCNB1,KCNJ5,MAP2,NPY,PDE4D,PFKFB2,RETREG1,PLCD1,PRKAR1B,RELN,SH3BP2,KANSL3,SNCA,PEG10,ZNF423,LHPP,ARC,SYN2,ZEB1,PCDHA6,SLC44A1,TRIO" Drug 5387_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASIC1,OGT,APOC1,PLA2G4C,N4BP2L1,KSR1,BAIAP3,CA4,CAMK2B,CBFA2T2,CACNA2D2,SULT4A1,AKAP7,CPS1,AATK,CSF1,TMCC2,EGR3,ELN,C3orf18,FHL1,TRAF3IP2,GATM,GLYR1,CACFD1,KCNN1,MSR1,MYO7A,PLCD1,POLG,MAPK7,PTN,CCDC40,RPS6KA2,RASA3,FRMPD1,FBXO11,SLC8A1,SMARCD3,PDZD2,DOK5,ZEB1,ZNF34,TIMP4,NT5M,ADAMTSL3,SENP7" Drug 2483_DN Cefaclor [70356-03-5]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "APBB2,CASK,STX16,BACH1,SYNJ2,CD86,SCARB1,TMEM184B,CRY2,CSF1R,PPP1R16B,RUBCN,DBT,TOM1,HIPK3,TUBD1,PTK2B,KAT8,GALC,INPP5K,GLYR1,LILRA2,PADI2,SCAMP5,GIT1,NFYA,SLC11A2,PLCD1,MINDY2,CNNM2,PTK2,PTPRN2,CEP97,ZNF821,SH3BP2,FNDC3A,FAM214B,NXT2,CEP68,ADGRL3,KIAA1107,ZEB1,ICAM5,PIK3R5,ZNF24,ZNF225,SENP7" Drug 4584_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "C1QTNF3,APC,BCAS1,ATP6V0A1,NRP2,CBFA2T2,ARHGEF2,CHN2,TAOK2,CREM,ABCG1,VCAN,PDE4DIP,RIMS2,DTNA,F5,ERGIC3,ZNF44,ERAP1,ADAM28,RAB30,GNG4,CNTRL,ICA1,ITGA7,LSS,SMAD1,NEK1,NF1,NOVA2,OPRL1,PFKFB2,RETREG1,LRRN3,PRKAR1B,PTCH1,ZSCAN32,MARCH1,ACSS3,RASA3,ST6GAL1,PPP4R3A,SLC11A1,SNCA,ASTN2,SMG6,MKRN3" Drug 6013_UP Tiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "LTBP4,KCNAB2,APBB2,GAS7,N4BP2L1,CFLAR,CACNA1G,CAMK2B,KCNAB3,CHN2,SULT4A1,FHL5,VCAN,RIMS2,DTNA,EDNRB,DLC1,DCTN2,FYN,GNAO1,PCLO,GRB10,ITGA7,MAP4,AFDN,NPY,NTRK2,RETREG1,GRAMD1C,PTPRO,ZDHHC14,TCP11L1,SH3BP2,ASAP3,SYBU,DZIP1,FAM214B,NMNAT2,PEG10,ATP10B,SYT5,DICER1,AP4E1,THRA,RUNDC3B,UCHL1,LAT2" Drug 5254_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,LTBP4,N4BP2L1,KSR1,BAIAP3,CD86,ARHGEF1,STOML1,CSF1R,VCAN,ARHGEF4,TMCC2,EGR3,REEP2,CORO2B,FGFR1,AGAP2,PDLIM5,GNAO1,GPER1,AFDN,NF1,CDK18,PDE1C,ENPP2,TMOD2,RELN,CNNM2,ZDHHC14,RET,KLHDC8A,RPS6KA2,ZFP2,ZNF821,NLGN1,FAM214B,MYH15,SNCA,ARHGAP26,IQSEC2,ARC,DMXL2,DNAH7,TMEM121,TK2,ZNF154,PARP11" Drug 3713_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADD2,BEGAIN,RASL11B,N4BP2L1,BMP7,SCAPER,BAIAP3,KALRN,FOXN3,HOMER3,NCOR2,PDE4DIP,SPOCK2,SV2B,ECM2,MBNL2,EPHB1,EFCAB2,FYB1,GABRG2,SIGLEC8,SRCAP,POLL,ADAMTS13,ICA1,LAMA2,NF1,MINDY2,PRKCB,PTPRN2,C1orf54,FAM184A,ZCWPW1,RFX2,RGS4,PBRM1,RPS20,KCNIP1,DGLUCY,DZIP1,SLC2A5,HECW1,SPP1,KDM4C,RPRM,OSBP2,LMF1" Drug 3743_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "SYN3,AMPH,CDC14B,PPP4R4,BMP7,FUBP1,HAP1,CLDN10,CD86,CRLF1,TAOK2,TPP1,CNTNAP2,MYEF2,RCAN1,EDN1,HIPK3,FER,FGFR1,AGAP2,SIGLEC8,SRCAP,GPD2,GRM8,TJAP1,ITPKA,NPTX1,CLDN11,BCAS3,PTPRN2,RFX2,KCNIP1,ZNF821,FNDC3A,SLC2A5,PKNOX2,RBM34,SPTAN1,SS18,ARC,ZEB1,CRTC1,TNS1,TRO,OSBP2,LAT2,SLC17A7" Drug 2898_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "SEMA6A,FAM131A,SEMA4G,SLC4A4,KIF1A,SCARB1,ARHGEF2,RCBTB2,ASIC3,VAX2,QKI,ABI3BP,NECTIN3,SOCS5,PDE4DIP,FAM169A,PHF14,DCAF4,MFAP3L,SLC12A6,OPTN,TRAF3IP2,CNTRL,TJAP1,INPP1,MAP4,GIT1,LYRM9,ZNF862,NF1,PCDH9,RETREG1,STRN3,POLG,PRPH,RGS3,SYBU,SLC6A8,TROVE2,CLSTN2,EXOC7,TBL1X,CHST8,UBE3A,ZNF24,DNALI1,RNF170" Drug 4346_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ALCAM,SEMA7A,GAS7,N4BP2L1,KALRN,COL9A3,ARHGEF10,DUSP9,CHL1,GABRG2,CPLX2,SRCAP,GFER,GPER1,TPPP,GRM2,IRAK3,NOVA2,PFKFB2,PURG,CEP41,MASP1,RELN,VPS13C,PTPRB,RASGRF1,RGS12,SH3BP2,BTBD7,HECW1,ZC3H13,SPART,ZC4H2,TBCEL,SYNE1,SLC35G2,DNAH7,TNS1,VIPR2,WIPF1,LAT2,ZNF154,SLC30A3,EMSY,SLC17A7,PLSCR4,FAM13C" Drug 5477_UP "Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,AP2A2,KIAA1324,ATP1A3,ALDH7A1,CFLAR,CACNA1I,BAIAP3,CFAP410,ARHGAP33,CPS1,DAPK1,HIPK3,HSD17B14,RASGRP2,ERBB4,ZNF589,FGFR1,BAIAP2,MALT1,STON1,GRM2,GUCY1B1,LIG4,MMP16,ADAM22,NELL2,NNAT,NPY,MINDY2,PTH1R,ELOVL2,KCTD17,RPS6KA2,SLA,ELMO2,ZKSCAN3,PDZD2,IZUMO4,ZC3H13,SS18,SYNE1,AP4E1,CHST5,ZKSCAN5,EVI5,FAM13C" Drug 5114_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASIC1,LTBP4,EPB41L5,APLP1,NRP2,CHN2,WHRN,CDC42BPB,ENTPD4,SH2B1,HAPLN1,CRY2,FAM131B,CHRDL1,TOM1,EDNRA,COQ7,NRN1,PDLIM5,CACFD1,ICA1,AFDN,MYCN,MYT1,NTRK2,RETREG1,MINDY2,MAPK7,CNNM2,TMEM231,FAT4,RASGRF1,RPS6KA2,ZNF821,FRMPD1,ASAP3,DZIP1,SLC4A3,ARHGAP26,DBNDD2,ZBTB43,COBL,ASTN2,SYT5,SZT2,ZNF34,LAT2" Drug 6631_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADRA1D,TRMT9B,AMPD3,APBB2,CDK13,PDE8B,DNAH17,SLC4A4,KSR1,TAOK2,CDON,FEM1B,ETV1,FGFR1,ZNF44,INPP5K,GLYR1,STON1,LPAR4,GPR37,GUCY1B1,BACH2,SHISAL1,TJAP1,KIF2A,IPO5,AFDN,ZNF862,GRAMD1C,PTCH1,PID1,FBXW7,ZFP30,LIMS2,BTBD7,SNCA,GLT8D1,DDN,SYT1,ASTN2,KIAA1107,SMG6,KLHL4,TMEM121,THRA,WIPF1,NT5M" Drug 2650_UP Androsterone [53-41-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASPHD1,KIAA1324,ALCAM,BEGAIN,DDO,PLA2G4C,MARK4,NUMB,CAMK2B,CAST,ARHGEF1,ARHGAP33,WHRN,CREM,NCOR2,ARHGAP24,C2CD2L,OPTN,ERBB4,ERCC2,FGFR1,SCARA3,INPP5K,GFER,PRRC2B,INPP5B,ITPKB,KCNF1,MGAT3,MX1,ENPP2,NLE1,MBOAT7,PPARA,MAPK7,PTN,ZSCAN2,NKAIN1,RGS12,FBXW7,SLC11A1,MAPKBP1,SPTAN1,TNS1,PDIA2,NDRG4,ITM2C" Drug 6723_UP Primidone [125-33-7]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "MTUS1,ADGRF5,C1QTNF3,BEGAIN,APC,CDC14B,MPDZ,FUBP1,SCAPER,CAMK2B,CACNA2D2,SOCS6,TAOK2,NCOR2,PHF14,RIMS2,FAM131B,DAPK3,MFAP3L,IGSF6,STON1,GRM8,KCNJ5,LSS,MAN2A2,TM6SF1,ADAM22,NELL2,NNAT,NOVA2,RETREG2,SH3TC2,ENOX1,FBXO11,PKNOX2,ARHGEF40,ZSWIM8,RGL1,PLCB1,COBL,TAL1,RPGRIP1L,CHST8,ZNF24,REEP1,KCNAB1,PARP11" Drug 4446_UP 2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "AK2,PKP4,KIF1A,CFLAR,CACNA1A,SULT4A1,FHL5,PDE4DIP,EDNRA,PLXNC1,TENM1,ETV1,REEP2,ZNF589,FLT1,GLI2,RAB30,GNAO1,IRAK3,ATXN2L,IRF8,KCNH2,MATN3,NOVA2,PILRA,CEP41,PTPRN,PTPRN2,SUSD4,GAL3ST4,RET,TCP11L1,KCNIP1,SH3BP2,CNKSR2,CXXC4,DDN,SYT5,MCF2L,ADGRL3,DMXL2,PCDHGA10,TNS1,NPL,OSBP2,FLRT2,FAM13C" Drug 7262_UP Alfadolone acetate [23930-37-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADCY6,AMPD3,LGR5,ARRB2,RUNX1T1,LRRFIP1,CRLF1,RCBTB2,SOCS6,LHX2,RAB28,NRXN3,COL9A3,RCHY1,CSF1,ARHGEF10,FAM13A,MTSS1L,COPS8,TDRKH,GPR37,GUCY1B1,MUM1,ICA1,SHISAL1,INPP5B,MIA2,MITF,MKLN1,NF1,NPTX1,PDE4D,PIK3R1,SLC25A23,PRKAB2,KCTD17,RPS6KA2,SLC14A1,SPART,SYP,ZEB1,R3HDM1,PARD3,CABIN1,TNS1,ZNF189,SEMA3B" Drug 4179_UP Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "SYN3,ALK,SLC4A4,ATP2B2,ADAM23,BACH1,CACNA1G,BAIAP3,CACNA1A,KALRN,CBFA2T2,CHRNA4,FAM149A,ARHGEF10,BRINP1,KLHL3,SPOCK3,EDNRA,FHL1,FLNC,DCTN2,ZNF44,SEPT9,GNAL,GRM8,IRAK3,HLF,IGF1,MID1,MYO7A,NOVA2,PDE4A,GPR85,PLXNB1,PPARA,SAMD9,PTPRB,KHDRBS2,RNASE1,SATB1,FRMPD1,TACR1,TEK,ZFPM2,CHST5,VSNL1,WIPF1" Drug 6722_UP Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "AMPH,PKP4,APC,NRP2,KSR1,SCAPER,CACNA1I,BAIAP3,CALB2,HAP1,TAOK2,HOMER3,FAM149A,CRMP1,SUSD5,CNTNAP2,MFAP3L,DOCK2,PLXNC1,F5,STON1,GRM8,HNMT,INPP5B,ITGA7,KCNF1,LSS,MAN2A2,TM6SF1,MIA2,PTN,GSTCD,KCNIP1,ZFP30,SH3BP2,FBXO11,SLC11A1,ATP10B,PLCB1,DOCK9,R3HDM1,TNS1,VIPR2,KCNAB1,FAM13C,NLRP3,GAN" Drug 5663_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA2A,APBA2,PPP4R4,ARHGDIG,HAP1,CAMK2B,STOML1,CPS1,CNTNAP2,CDON,SHANK1,EDNRB,DLC1,FGFR1,AFF2,DCTN2,ERAP1,ICA1,INPP5B,KCNH2,AFDN,MMP16,NF1,CNOT4,NPTX1,P2RY1,PDE1C,PFKFB2,RETREG1,C19orf57,LRRN3,GDPD2,PTX3,CEP97,ZMAT4,SH3BP2,MAPKBP1,PDZD2,ZC3H13,CLSTN2,SLC35G2,TLR4,PIK3R5,VLDLR,SLC30A3,NT5M,SLC17A7" Drug 6763_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASPHD1,PKP4,SLC4A4,CFAP410,CACNA2D1,SCARB1,SYNGR3,LARGE1,CNTFR,DAPK3,MFAP3L,DTNA,DUSP9,TENM1,RASL12,DLC1,FGF1,DCTN2,ALDH1L1,GRIK5,MAN2A2,ADAM11,TM6SF1,P2RY13,NNAT,PDE4D,RETREG1,PTCH1,PTPRH,TMEM231,C1orf54,GAL3ST4,RET,RGS12,FBXO11,KDM4B,ATP10B,SSTR2,COBL,DOCK9,TK2,CABIN1,HIRA,EMSY,KCNAB1,PARP11,EPM2A" Drug 4764_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "RALGAPA1,ASIC1,BEGAIN,AMPD3,SEMA7A,PDE8B,ASIC3,AKAP7,CRMP1,AATK,CSF1,ARHGEF10,VCAN,C2CD2L,SPOCK3,TMCC2,ERCC2,PTK2B,FGF13,FHL1,CSPG5,ZNF44,DISC1,RUNDC3A,RAB30,TDRKH,TJAP1,IL6R,KCNH2,KIT,NTRK2,PLCD1,PLTP,ELOVL2,NKAIN1,RGS12,TCP11L1,EMID1,ASAP3,SMARCD3,PDZD2,ARHGAP26,ATP10B,TBL1X,CRTC1,TK2,UGT8" Drug 7398_UP Merbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,MTUS1,AMT,APC,GAS7,PDE8B,RAB26,AATK,VCAN,EXOG,EDN1,HIPK3,IRAK4,ING4,MTSS1L,ANKMY1,TAOK3,DLC1,FGF13,SEMA4D,DENND2A,SIGLEC8,CSDC2,GLI2,SOX21,SHISAL1,IL12A,KCNJ5,NPR2,CLDN11,PDE4D,CNNM2,ZSCAN32,PTPRE,ZDHHC14,KCTD17,FBXW7,SEMA6D,ASAP3,MYH15,KDM4B,TSNAXIP1,CEP68,PHLDB1,KLHL4,ZKSCAN5,UBE3B" Drug 3324_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASIC1,ADORA1,NME5,LTBP4,AMPD3,KCNAB2,CDK13,KSR1,LDLRAD4,CFAP410,FOXN3,NRG2,SNCAIP,RIMS2,DAPK1,SPOCK2,DMD,EDN3,MBNL2,PLXNC1,LRRC17,FGF12,FGFR3,KHDRBS3,FYN,DISC1,HLF,IL6R,TAGLN3,STRN3,NECAB2,SAMD9,C1orf54,KHDRBS2,RGS3,RGS12,RASA3,SLC9A5,ZNF415,ARHGAP26,ARC,TRIM2,DOCK9,TK2,LAT2,KCNAB1,TIGD6" Drug 5220_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "CDC42BPA,APBB2,DNAH17,KSR1,SYNJ1,SYNJ2,SCAPER,CDH2,FOXN3,SOCS6,ARHGEF6,CREM,VCAN,SEC14L5,INTS1,TMCC2,MBNL2,ING4,RASGRP2,SRCAP,RUNDC3A,GLYR1,RAB30,POLL,GRB10,GRIK5,ICA1,IFI16,IL6ST,MAP2,ADAM22,ZNF862,NF1,CDK18,LRP12,CCDC40,GAL3ST4,FUZ,KANSL3,STX1A,ARC,PCDHA5,TNS1,TRIO,LAT2,XRCC4,TIGD6" Drug 426_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "NDRG2,APC,ARRB1,SLC4A4,ADAM23,ADAM15,ARHGEF7,CBFA2T2,CLCN3,CNTFR,ABCG1,AATK,MED12,EPB41L2,STX2,TRMO,POMT1,PDLIM5,ALDH1L1,RUNDC3A,GLYR1,CNTRL,BTN2A1,PTPRT,GSN,SCIN,KHK,MBNL1,MYO6,PFKFB3,CCSER2,MBOAT7,MTMR10,RNASEL,RXRA,SH3BP2,SLC2A5,PKNOX2,SNCA,NMNAT2,MYCBP2,SSTR2,NXT2,PLCB1,TRIO,NDRG4,VPS35L" Drug 3196_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,KIAA1324,ALCAM,APAF1,ARHGDIG,SYNJ2,HAP1,ARHGAP33,CHN2,B4GALT6,EPS15L1,IPCEF1,VCAN,PDE4DIP,MFAP3L,DUSP9,FEM1B,ETV1,F5,REEP2,PDLIM5,FYB1,PCDH17,GLYR1,GNAO1,GRIN2D,GSTM5,JAK2,KCNJ5,LSS,MAPT,AFDN,ADAM22,MSR1,CLDN11,PPP5C,RPS6KA2,SLC4A3,FAM214B,ZNF423,PLCB1,EXOC7,ADGRL3,SLC35G2,WIPF1,XRCC4,SLC30A4" Drug 5383_DN Pralidoxime chloride [51-15-0]; Down 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "RALGAPA1,NME5,C1QTNF3,NUMB,CFLAR,CFAP410,CA12,SCARB1,SLIT2,ENTPD4,ABCG1,TBC1D5,DAPK3,DBN1,FEM1B,OGA,GCNT2,GNG4,PRRC2B,SPACA9,GRIK5,HNMT,IL6ST,KCNH2,IPO5,MITF,CNOT4,PRODH,ELOVL2,RGS12,CCDC25,EPN2,SPTAN1,TROVE2,ST5,CEP68,VPS13A,MCF2L,CRTC1,TMEM121,AP4E1,SLC44A1,TK2,PLPPR2,ZBTB14,ZNF45,SMIM8" Drug 3727_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADGRF5,PPFIA3,CDK13,ADGRB2,CACNA1A,CAST,LARGE1,FOXN3,LHX2,CNTNAP2,RUSC2,DMPK,DTNA,ING4,FGF1,FGFR1,PDLIM5,TRAF3IP2,B4GALNT1,SEPT9,HTATSF1,KCNMB4,GNG4,FERMT2,CACFD1,ELOVL5,IL6ST,MBD1,NFIX,NPR2,CEP41,PTCH1,RPS20,ZNF821,BTBD7,SNCA,TSNAXIP1,DOK5,IQSEC2,CEP68,SMG6,DOCK9,CHST8,VIPR2,VLDLR,WNT7A,TIGD6" Drug 5059_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ALK,AMPD3,KCNAB2,ADAM23,RGS9,CBS,CCK,CRLF1,ASIC3,IQCK,CABP1,MYRIP,RIMS2,DAPK3,DRP2,COQ7,MTSS1L,APC2,FGF12,AGAP2,SIGLEC8,LYVE1,GPD1,KCNN1,KIFC3,LIFR,MYT1,NRCAM,P2RX7,ABCB1,RETREG1,PPARA,MAPK10,WDR25,RGS4,MRAS,CPEB3,SLA,ZNF334,DDN,TBCEL,PHF24,CHST5,TRO,RPRM,FLRT2,FAM13C" Drug 1203_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "STX16,ATP2B2,ATP6V0A1,KSR1,SCAPER,CACNA1I,CFAP410,CAST,EPS15L1,RAB28,QKI,ENTPD4,CSF1R,MFAP3L,TMCC2,CDON,CNNM1,ING4,MRNIP,FGFR1,SEMA4D,PDLIM5,PRELID3A,FYN,GNAL,CACFD1,RNFT2,ICA1,SHISAL1,IL6ST,LYRM9,NTRK2,PRKAR1B,CNTLN,PTN,ZSCAN32,PTPRE,SEMA6D,CSRNP3,SLC4A3,PEX26,IQSEC2,LHPP,HIRA,WIPF1,SH3GLB2,PHTF2" Drug 4353_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA1,ALK,CDC42BPA,APOC1,ARHGDIG,ATP2B2,ARHGEF2,CLTB,SULT4A1,CRMP1,SUSD5,DCAF4,DGKG,DUSP9,ERBB4,SPEG,DENND2A,GAD1,ALDH1L1,GPER1,SOX21,ATXN2L,LIFR,LSS,MAP4,MMP17,NEFM,NTRK3,CDK18,PGAM2,CEP41,PTPRO,RFX2,RGS4,RORB,SH3BP2,ASAP3,CNKSR2,SLC11A1,PDZD2,PEG10,ARHGAP26,ATP10B,RGL1,R3HDM1,SLC30A3,ADAMTS9" Drug 2099_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "STX16,MTMR3,SLC16A4,SCARB1,QKI,ARMC8,CSF1R,SLITRK5,DCAF4,FCF1,MTSS1L,SEMA4D,EFCAB2,POLL,ATXN2L,INPP5B,LMO2,MMP16,MPP2,NF1,CNOT4,NOVA1,NOVA2,PALM,PCDH9,LRRN3,MAPK7,PRPH,ELOVL2,PTPRN2,SUSD4,GAL3ST4,KCTD17,RPS6KA2,ZFP30,ASAP3,ARHGEF40,CCDC88A,FNBP1,SPTB,ZBTB43,TBL1X,GPR161,CABIN1,TRO,LMF1,LAT2" Drug 5391_DN Chlorpropamide [94-20-2]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ASPHD1,APBB2,CDK10,ARHGEF2,CLGN,SRSF11,IQCK,BAG4,CRY2,DBN1,DBT,DTNA,MBNL2,KAT8,FER,PDLIM5,GCNT2,RUNDC3A,GNG4,MUM1,ATXN2L,ELOVL5,AGFG1,INPP5B,KIF2A,KITLG,LRP12,FSD1,PRODH,RGS12,NEK11,SEC14L1,SUPT20H,SH3BP2,FBXO11,ANKRD6,KIF13A,RBM34,UNC5B,TROVE2,ST5,TTBK2,PLCB1,SLC44A1,TK2,TPM1,MAP3K12" Drug 6479_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "AK2,BIN1,GAS7,PLA2G4C,MARK4,ATP6V0A1,ADAM15,GYG2,BAIAP3,CACNA1A,CALB2,CCNT1,HOMER3,BAG4,ENTPD4,GREB1,DAPK3,DTNA,EDNRA,FCF1,MBNL2,PLXNC1,MTSS1L,KAT8,GCNT2,POLL,STON1,KCNF1,KPNA5,IPO5,NFYA,P2RY1,ZSCAN32,KHDRBS2,RNASEL,ATXN2,ZNF821,PREX2,PEX26,ELMO2,TROVE2,ARC,CRTC1,VIPR2,VLDLR,XRCC4,SPHK2" Drug 4976_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "ADORA2A,AP2A2,APC,ST3GAL5,SYNJ2,CAMK2G,FOXN3,SLIT2,TPP1,ABI3BP,RCHY1,ARHGEF4,KIAA0586,TOM1,FEM1B,SUGP2,TNK2,MRNIP,DLC1,KAT8,CGREF1,GCNT2,PCLO,DIDO1,KCNN2,MID1,MMP16,MSI1,ZNF862,NF1,NPR2,SETD4,PLCD1,SAMD9,ZCWPW1,RGS3,SBF1,ZNF821,ARHGEF9,EXOC7,DICER1,TMEM121,CABIN1,FAM155A,UBTF,PLPPR2,EVI5" Drug 4661_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "AGT,NME5,BIN1,APBB2,SYNGR3,PLEKHB1,PLAA,RAB26,CREM,SH2B1,VCAN,ARHGAP32,KIAA0753,EXOG,DTNA,EDN1,EDNRA,EFCAB2,FYB1,ZNF44,GAD1,ERAP1,GLUL,GUCY1B1,TJAP1,KIF2A,MAPT,CNOT4,LRP12,PPARA,TMEM231,MCMBP,RPS6KA2,ATXN7,SUPT20H,FRMPD1,SLC14A1,TSNAXIP1,KDM4C,UNC5B,CRTC1,TIAM1,UBTF,WNT7A,XRCC4,KCNAB1,PHTF2" Drug 5087_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "RALGAPA1,TRMT9B,PPP4R4,PDE8B,DNAH17,SLC4A4,SLC2A11,N4BP2L1,GYG2,LDLRAD4,FOXN3,VAX2,RAB26,ARHGEF10,CNTNAP2,DTNA,FGF1,AGAP2,PDLIM5,ERAP1,SEPT9,GLI2,SOX21,BACH2,ELOVL5,ICA1,IL6R,FAM69A,AFF1,NOVA2,NRCAM,PALM,GRAMD1C,TMEM231,SH3TC2,C1orf54,KHDRBS2,KCTD17,AMBRA1,ST6GAL1,TMCC1,ZBTB43,MCF2L,SYNE1,VSNL1,SPHK2,KCNAB1" Drug 4627_DN Altretamine [654-05-6]; Down 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "TRMT9B,AMPD3,PDE8B,ADGRB2,LDLRAD4,B4GALT6,SLC4A8,DCAF4,SGSM2,DTNB,FEM1B,MBNL2,MRNIP,MTSS1L,STX2,GCNT2,ARFIP1,ZNF276,GNAL,TJAP1,LIG4,MAPT,MGAT3,NDP,NEK1,NOVA1,PDE1C,PDE4B,PTPRB,ATXN2,ATXN7,ZFP30,FRMPD1,MYH15,TMCC1,TSNAXIP1,ARHGAP26,SPTAN1,JMJD6,EXOC7,CRTC1,THRA,TK2,BHLHB9,RIMBP2,AMACR,KCNAB1" Drug 4464_DN 2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.34E-07 2.78E-02 3.76E-05 4.24E-04 47 198 "RALGAPA1,CDC42BPA,APAF1,PPP4R4,ATP1A3,SCAPER,CACNA1I,CSF1,MFAP3L,DMPK,EGFR,ING4,MRNIP,FGF12,HPCAL4,PDLIM5,NEU3,GNG4,SPACA9,PADI2,ATXN2L,KCNQ3,KITLG,NF1,NFIX,CNOT4,NRCAM,PDE4D,PLCB2,LRRN3,PPP5C,PRKAR1B,PTPRB,TMEM231,KCTD17,MRAS,SLA,PPP4R3A,SMARCD3,UNC5B,TBCEL,ZNF24,NT5M,EVI5,KAT6A,PHTF2,GAN" Drug 3868_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.74E-07 2.95E-02 3.99E-05 4.50E-04 42 169 "ABHD6,ADRB2,NME5,APLP1,ST3GAL5,BAIAP3,CLGN,WHRN,PDE4DIP,ARMCX2,TMCC2,FAM13A,RASGRP2,HPCAL4,FYN,CYP46A1,RAB40B,GSN,LSS,MEF2C,MPP2,NEK1,TMOD2,SERPINI1,GRAMD1C,PRPH,RPS6KA2,SH3GL3,ASAP3,WDR47,FAM214B,PEG10,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug ctd:C005556 propionaldehyde CTD 6.92E-07 3.04E-02 4.10E-05 4.61E-04 293 1982 "VWA5B2,ELFN2,GALNT16,ADORA2A,UNC5A,RNF150,ADRB2,ZNF608,KLHL13,AGT,KIAA1324,OSBPL6,SRPX,CARNS1,MARCH4,PDZD4,AMPD3,AMPH,LRFN1,LRCH2,PI16,CCDC146,PPFIA4,DDO,SHROOM2,CDK10,SFMBT2,PPP4R4,IGDCC4,ZFYVE28,ARRB1,LINC00173,ASGR1,MARCH3,STK33,PTCH2,TMEM108,RNF182,KIF1A,ADGRB1,BARD1,RGS9,BLM,GPR146,BMP7,ST3GAL5,CACNA1I,CACNA1G,BAIAP3,CA4,CACNA1B,CAPN3,PRC1,CCK,DCLK1,EVI5L,TIGD7,CRLF1,CACNA2D2,PLEKHB1,MS4A7,ARHGAP22,NGEF,FAM189A2,RAB26,CCDC151,CABP1,GAL3ST1,CRYM,CSF1R,CSF2RA,RIMS4,PDE4DIP,PPP1R16B,ARHGEF4,DOCK4,RASSF2,SPOCK2,AIF1L,KIAA0319,TMEM130,LYPD1,KIF19,DMD,NR1D2,EDN3,RASGRP1,TMTC1,FRY,FAM13A,EBI3,MRO,AASS,ENO2,RASGRP2,SLC43A2,ZNF549,ADGRV1,MRVI1,F5,REEP2,ZNF585B,CEP78,GTF2IRD2,FGF13,TMEM164,HPCAL4,AGAP2,AFF2,FLYWCH1,EFCAB2,SMC2,PDLIM5,NSG1,FYN,MEGF11,GAD1,DISC1,CPLX2,ALDH1L1,SULT1C4,SESN1,KCNMB4,GNAO1,STON1,ATP2B1-AS1,C1QL4,PLPP7,GRIN2C,CIT,LINGO1,ADAMTS6,GUCY1B1,SLC2A6,TOX2,PADI2,NXPH3,FRMD5,SYNPO,CPT1C,CELF5,ICA1,NKD1,ITGA7,KCNH2,KCNN1,KCNN3,L1CAM,TTYH2,LAMA2,STMN1,LMO2,GPR155,MAP6,MAPT,CHST6,ADAM11,MKLN1,COL28A1,LAYN,MYT1,FXYD7,NEFM,NEFH,NOVA2,NPTX1,NPTX2,KSR2,PAX6,GPR173,ZDHHC8,DUSP26,NALCN,RETREG1,TMEM38A,KCTD15,JAKMIP1,PLIN1,SDK2,NECAB2,ING3,SEPT4,FA2H,SKOR1,MAPK4,GRAMD1C,SMIM10L2B,PRPH,GDPD1,SAMD9,LAMA1,PTPRN,PTX3,PID1,TMEM255A,C1orf54,FAM184A,ENOX1,RASGRF2,RADX,CRTAC1,RET,SUGCT,KLHDC8A,SNX22,EPHA10,ARMH4,ZNF671,RPS6KA2,PLPPR3,MEG3,ZNF568,TNFRSF19,SMPD3,ZFP2,TMEM200C,PEAR1,GALNT10,STUM,ARX,SHC4,HKDC1,FHOD3,ABLIM3,LIMS2,SLC6A8,SLC14A1,MAST1,OGDHL,SNCA,MBD5,SNRPN,NMNAT2,UNC5B,TSPYL2,NFASC,THSD1,SSTR2,ELOVL4,STAC2,SULF2,SEPT3,ADAMTS17,ARC,SYN2,COBL,ASTN2,CAMTA1,WSCD1,NEU4,PCDHGB1,PCDHB10,PCDHB6,OBSL1,PCDHA3,PCDHA1,VWCE,DNAH7,ITGB3BP,ENHO,TIAM1,NACC2,HEY1,ICAM5,TMPO,BEX4,PIK3R5,TPM1,NPL,LRRC24,TRO,ZNF709,VAV1,VGF,LMF1,LAT2,NDRG4,CELF4,DPYSL5,SLC30A3,CADM2,LINC02210,PRDM8,NAV3,HRASLS,DNAH10,TMEM63C,CASC15,ADAMTSL3,NLRP3,ADAMTS10,PRRT4,JPH3" Drug 2835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.95E-07 3.05E-02 4.10E-05 4.61E-04 43 175 "NME5,ALCAM,ST3GAL5,SPAG9,CLGN,PDE4DIP,ARMCX2,TMCC2,TSPAN5,OPTN,MBNL2,RASGRP2,FYN,CYP46A1,TDRKH,STON1,MITF,MPP2,PCDH9,TMOD2,SERPINI1,PKIA,GRAMD1C,PRPH,SH3BGR,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,ZEB1,TRIM2,HEY1,RUNDC3B,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 3746_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.95E-07 3.05E-02 4.10E-05 4.61E-04 43 175 "ABHD6,ADRB2,MTUS1,EPB41L5,ARNTL,ST3GAL5,HAP1,USP2,CBFA2T2,ABCG1,PDE4DIP,CNTNAP2,CTH,PLPPR4,EDN1,MBNL2,RGS17,TAOK3,BAIAP2,FYN,STON1,ITGA7,KCNH2,LIFR,MAPT,MMP16,PCDH9,ENPP2,SERPINI1,RETREG1,ENOX1,RGS4,SH3GL3,NFASC,ELOVL4,CEP68,RGL1,SYT1,SSBP2,TRIM9,SLC17A7,PLSCR4,PHTF2" Drug 2507_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.95E-07 3.05E-02 4.10E-05 4.61E-04 43 175 "C1QTNF3,BIN1,GAS7,MADD,DNAH17,CD86,CD38,CHN2,COL9A3,CREM,CRMP1,CSF1R,SIPA1L1,DZIP3,DOCK4,SPOCK2,AASS,BAIAP2,HPCAL4,SIGLEC8,MSTN,KIT,MEF2C,NRCAM,TREM2,PDE4B,PDE4D,CCSER2,MAPK7,BCAS3,SUGCT,TCP11L1,SEMA6D,SEC14L1,SH3BP2,ARHGEF40,SLC11A1,IZUMO4,TACR1,CRTC1,TK2,TRO,KCNK12" Drug 5822_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.13E-07 3.12E-02 4.19E-05 4.72E-04 44 181 "ABHD6,ADRB2,NME5,CDC14B,ARNTL,ST3GAL5,HIP1R,CHN2,ABCG1,VCAN,CTH,C2CD2L,PLPPR4,FAM13A,MRNIP,RGS17,TAOK3,SEMA4D,FYN,GUCY1B1,FAM69A,KCNF1,LIFR,MAPT,MMP16,TAGLN3,PCDH9,SERPINI1,RETREG1,PRPH,PID1,RGS4,FBXW7,SH3GL3,ASAP3,FAM214B,ELMO2,ARHGAP26,THSD1,ELOVL4,RGL1,SYT1,UBE2H,TRIM9" Drug 1047_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.26E-07 3.18E-02 4.21E-05 4.74E-04 45 187 "ABHD6,CDC42BPA,CDC14B,BMP7,ST3GAL5,RAB29,WASF1,SYNGR3,UBE2L6,FOXN3,RUBCN,KIAA0586,ARMCX2,TSPAN5,OPTN,STX2,EXTL2,ARMCX1,FAM49B,CSPG5,FYN,KCNMB4,GRB10,KHK,MAPT,MITF,MPP2,MXI1,OGG1,PDE4A,RETREG1,PRPH,PTCH1,SUSD4,MORC4,PPM1E,FBXO11,SYBU,CCDC88A,ELOVL4,STXBP1,SIN3B,TRIM2,BEX4,NDRG4" Drug 5600_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.35E-07 3.22E-02 4.21E-05 4.74E-04 46 193 "NDRG2,ADORA1,AMT,APAF1,SEMA4G,RAB29,SYNGR3,CLGN,RIMS2,RASSF2,ARMCX2,DMD,FRY,ELN,PDLIM5,CSPG5,FYN,GAD1,SRCAP,MAPT,MYO7A,NF1,CDK18,TMOD2,LRP12,ASAP3,CPEB3,ARHGEF40,LIMCH1,SNCA,NMNAT2,HECW1,ZNF423,SPTB,SPART,ATP10B,ST5,ELOVL4,DMXL2,TRIM2,RPGRIP1L,BEX4,VGF,LAT2,REEP1,SLC30A3" Drug 1480_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.35E-07 3.22E-02 4.21E-05 4.74E-04 46 193 "SEMA6A,BIN1,CDC42BPA,APBB2,APOC1,PPP4R4,RGS20,ARRB2,SLC4A4,BACH1,MPDZ,CFLAR,ST3GAL5,SCAPER,CALB1,ARHGAP33,STOML1,QKI,COL4A5,CREM,LYPD1,DPYSL2,EDNRB,APC2,FGF13,FGFR1,IQCG,GHR,STON1,KCNN1,MEF2C,KITLG,NF1,NPTX1,CEP41,PRKAR1B,CEP97,FAM184A,FBXO11,PPP4R3A,KDM4B,SPTB,SPART,CRTC1,BEX4,WIPF1" Drug 5922_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.35E-07 3.22E-02 4.21E-05 4.74E-04 46 193 "ASPHD1,MTUS1,LTBP4,CDK10,ADGRB2,SYNJ2,MAGI1,TPP1,STOML1,NCOR2,ARHGEF10,PDE4DIP,CNTNAP2,FAM131B,SPOCK2,CDON,TOM1,NCALD,EZH1,KAT8,ZNF589,FGFR1,HPCAL4,ZNF44,ERAP1,ADAM28,KCNMB4,GPER1,PADI2,ATXN2L,KCNN2,NF1,NFYA,NOVA1,CDK18,GPR85,CNNM2,PTN,GSTCD,RPS6KA2,SALL1,FBXW11,TRIO,ZNF225,EVI5,PCBP4" Drug 5680_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "AMPD3,CALB2,RUNX1T1,SLC16A4,FOXN3,ARHGEF6,NCOR2,ARHGEF4,HDAC9,RIPOR2,BRINP1,ELMO1,TMCC2,EDNRA,EDNRB,EGFR,RASGRP2,FHL1,DCTN2,GFER,PCLO,GSN,IRAK3,HNMT,ADAM11,ADAM22,LYRM9,PDE4A,ENPP2,PRKCB,DCHS2,PTX3,GAL3ST4,KLHDC8A,ZNF821,SH3BP2,PKNOX2,CXXC4,MAPKBP1,ZC4H2,JMJD6,SYT5,TCF4,SYNE1,PHF24,CRTC1,ADAMTS9" Drug 3552_UP Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADORA2A,LTBP4,BIN1,APBA2,KCNAB2,APC,SEMA4G,CA4,ASIC3,CHN2,TPP1,AATK,CSF1R,CNTNAP2,GREB1,RIMS2,DGKG,PTK2B,FLNC,AFF2,ERAP1,DISC1,GNAO1,ADAMTS13,ELOVL5,KCNH2,KCNN1,KCNQ3,MEF2C,MX1,MYO7A,NF1,PDE1C,TRHDE,PTN,RGS12,TCP11L1,ABLIM3,PDZD2,ZC3H13,SPTAN1,PLCB1,TBCEL,HEY1,TUBB1,SPHK2,SEMA3B" Drug 2483_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "AMH,BIN1,PKP4,PPFIA3,PLA2G4C,MPDZ,BAIAP3,SEPT7,CHN2,LHX2,ABI3BP,ENTPD4,CRMP1,DCAF4,MFAP3L,RUSC2,KLHL3,HS3ST2,DTNB,MBNL2,RASGRP2,TBC1D16,AGAP2,KHDRBS3,DLL3,SEPT9,GATM,FAM107A,SYNPO,MAP4,LRRN3,GRAMD1C,RGS4,CLSTN2,ASTN2,TRIM2,RPGRIP1L,PCDHGA10,PCDHA5,PARD3,TRIO,LMF1,VSNL1,MAP3K12,SLC17A7,KAT6A,GAN" Drug 7210_DN Milrinone [78415-72-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ASPHD1,ABHD6,ADCY6,ARRB2,CFLAR,RAB29,CCNT1,SCARB1,LHX2,QKI,IQCK,SOCS5,PDE4DIP,DZIP3,TBC1D5,FBXL5,DNM1,SEZ6L2,EDNRA,SUGP2,EGFR,COQ7,VPS26C,FGFR1,ATP2C1,B4GALNT1,ERAP1,TXNL4A,MBD1,MPP2,NCAM2,PDE4A,RETREG1,MBOAT7,TMEM104,FBXW7,RXRA,MAPKBP1,ITPRID2,ELOVL4,ARHGEF9,TACC1,METTL3,UBE3A,LMF1,PRDM10,EPM2A" Drug 5954_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "RALGAPA1,ABR,AP2A2,NME5,AK2,AMH,SEMA7A,APOC1,CDC14B,PLA2G4C,DNAH17,SLC4A4,ATP6V0A1,TPP1,DAPK3,JAKMIP2,TMCC2,IGSF6,ACSL4,KHDRBS3,GPER1,SPACA9,GRM2,INPP5B,KCNN1,MATK,MMP16,ADAM22,MX1,MYO7A,NNAT,P2RY1,PCDH9,RETREG1,NECAB2,MAPK10,GSTCD,SLC11A1,SPTB,IQSEC2,NSFL1C,FAM189A1,THRA,TMPO,RUNDC3B,SPHK2,NT5M" Drug 4979_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "AK2,EPB41L5,ATP6V0A1,CFLAR,QKI,ENTPD4,PPP6R2,GIT2,C2CD2L,EXOG,DTNA,E2F5,CELSR3,COQ7,VPS26C,TPK1,PRELID3A,OGA,DIDO1,SLC2A6,HNMT,IL6ST,INPP5B,ITPKB,JAK2,LMO2,MAP4,ADAM22,NPTX1,PLCD1,PLEC,POLG,MINDY2,MAPK7,ZCWPW1,ATXN2,ABLIM3,UNC5B,SPTAN1,CAMTA2,ASTN2,RPGRIP1L,ZNF34,SLC44A1,KAT6B,TRIO,REEP1" Drug 2287_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADGRF5,AMPD3,BIN1,CDC42BPA,MARK4,CFLAR,SYNJ2,MTMR3,BAIAP3,SLC16A4,HAPLN1,MFAP3L,EXOG,HSD17B14,LRRC17,STX2,ZNF589,OLFM1,MALT1,GRB10,GRM8,HLF,AGFG1,KPNA5,MAP2,MAP4,MEF2C,ADAM22,NNAT,NPY,C19orf57,MAPK7,ZNF821,SH3BP2,SLC2A5,CCDC88A,COA1,FAIM2,SOX15,PRRC2C,WSCD1,TCF4,CRTC1,PCDHA5,TRPM2,FLRT2,EVI5" Drug 4584_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ASIC1,KCNAB2,APC,CDK10,ADGRB2,SYNJ2,CACNA1A,SYNGR3,TPP1,RAB26,CPS1,HAPLN1,AATK,RUSC2,PARD6A,DMPK,MBNL2,FYN,GAD1,GLI2,MAP4K5,ATXN2L,DHX35,MIA2,CNOT4,CNNM2,SAMD9,CNTLN,PID1,RGS3,ZNF671,TCP11L1,ZNF821,FUZ,FBXO11,ARHGEF40,CDK5RAP2,TROVE2,SAMSN1,PLCB1,PDLIM2,KIAA1107,SYNE1,TNS2,CHST8,TNS1,UPF3A" Drug 3633_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADD2,ARHGDIG,CDK13,ATP2B2,N4BP2L1,CACNA2D1,CALB2,NCOR2,VCAN,TMCC2,EDIL3,SPEG,APC2,ABCA8,OLFM1,SCARA3,AFF2,KHDRBS3,DENND2A,GNAL,LILRA2,ADAMTS13,SOX21,GUCY1B1,TJAP1,ITGA7,KIFC3,LAMA2,MGAT3,NINJ2,PDE4D,GPR85,NECAB2,RGS4,ZNF671,RASA3,FRMPD1,DZIP1,SLC2A5,PHLDB1,THRA,TNS1,TRO,FLRT2,VIPR2,SPHK2,SLC17A7" Drug 2906_DN Meptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "NDRG2,KCNAB2,RIPK1,ADAM15,BCL7A,SLC16A4,SCARB1,CNOT8,RAB28,CLCN3,TM9SF4,C2CD2L,HIPK3,FCF1,VPS26C,ZNF589,IDH3A,IPO5,SMAD1,MAP4,N6AMT1,NEFH,PIK3R1,CCSER2,DEF8,TMEM231,SUPT20H,HSPA4L,KBTBD4,TMCC1,KDM4B,THSD1,STX1A,EXOC7,PDLIM2,TCF4,AP4E1,PARD3,TRPS1,HIRA,ZNF32,TFIP11,NT5M,GDPD5,HPS4,PHTF2,NLRP3" Drug 6668_UP Bemegride [64-65-3]; Up 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "AK2,SYT13,CDK13,ATP6V0A1,AZGP1,ADGRB2,RGS11,CFLAR,MYRF,BAIAP3,CACNA2D1,HAP1,HIP1R,RUNX1T1,CACNA2D2,TAOK2,HOMER3,SH2B1,PDE4DIP,MYEF2,DTNA,DUSP9,EDN1,ETV1,FAM198B,OLFM1,SIGLEC8,GNAO1,AP4S1,ITGA7,KCNJ5,KCNQ3,MAP2,ADAM22,MYT1,RETREG1,LRRN3,PRPH,PSD,RASA3,SLC11A1,SNCA,PHLDB1,ASTN2,SZT2,PHF24,R3HDM1" Drug 1699_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "BIN1,APBA2,PPP4R4,SLC4A4,ATP6V0A1,SCAPER,CACNA1I,CA4,HAP1,CACNA2D2,SLIT2,SLC4A8,NECTIN3,DAPK3,NR1D2,EDNRA,PLXNC1,PLEKHA1,ZNF589,ERAP1,CSDC2,GLYR1,TDRKH,MAP4,MBD1,MSI1,NF1,NFYA,SETD4,PDE4A,NLE1,PLCD1,PMP22,WDR25,GTDC1,SCN8A,STUM,ASAP3,PKNOX2,SNCA,SPART,STX1A,PLCB1,ARC,ZKSCAN5,VIPR2,GDPD5" Drug 3320_UP Nitrofural [59-87-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ABHD6,ADRA1D,BIN1,CDC42BPA,APBA2,APC,APLP1,BAIAP3,CRLF1,STOML1,SULT4A1,ABI3BP,CSF1R,ARHGEF10,CNTNAP2,MFAP3L,LRRC17,FGFR3,FHL1,FLNC,POLL,GNG4,GRM8,IRAK3,KCNJ5,AFDN,ADAM22,MYT1,P2RY1,PURG,LRP12,SAMD9,C1orf54,ASAP3,NLGN1,SLC11A1,CLSTN2,PCDHGA10,SYNE1,OBSL1,TRIO,VIPR2,WIPF1,SPHK2,NT5M,TIGD6,JPH3" Drug 6491_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "RALGAPA1,ADORA2A,ATP6V0A1,ADAM23,KSR1,GYG2,CFAP410,CACNA2D1,CDH2,CLGN,STOML1,HOMER3,ARMC8,CSF1,PDE4DIP,MAML1,SPOCK2,DTNA,MBNL2,APC2,RRAGB,F5,SCARA3,DCTN2,PRELID3A,OGA,GCNT2,RUNDC3A,GSTM5,SOX21,KCND2,MID1,MYO7A,PLCD1,SAMD9,CCDC40,TCP11L1,SH3BP2,UNC5B,PHLDB1,SMG6,WSCD1,CRTC1,SLC44A1,PIK3R5,SLC30A3,DNALI1" Drug 6657_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ASPHD1,ADORA2A,ADRA1D,AMPH,LGR5,ATP2B2,ADGRB2,BAIAP3,SLC16A4,CD86,EPS15L1,NRXN3,ARHGEF10,SUSD5,C2CD2L,EDN1,ING4,ETV1,OLFM1,OGA,GATM,POLL,ATXN2L,MMP16,PALM,PDE4B,ENPP2,POU6F1,GDPD2,PTN,TMEM231,FAM184A,RASGRF1,RGS12,FBXW7,SLC6A8,SLC9A5,ZNF334,ZHX3,KDM4C,SPTB,RBM26,SYN2,MCF2L,CRTC1,RIMBP2,HIRA" Drug 5104_UP Flumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADORA1,APC,BCAS1,PRX,ADAM23,BMP7,MTMR3,MYRF,FOXN3,LHX2,HAPLN1,NCOR2,MFAP3L,RASGRP2,PTK2B,ZNF44,DISC1,LILRA2,LPAR4,CACFD1,ICA1,ITGA7,KCNN2,KCNQ3,MGAT3,MX1,GPR85,RETREG1,ZSCAN2,KHDRBS2,GAL3ST4,RGS12,KCTD17,RNASEL,PNMA8A,ZNF821,RASA3,ST6GAL1,SLC2A5,SNCA,KDM4B,ZBTB43,TK2,TNS1,TPM1,VIPR2,MPPE1" Drug 5538_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "RALGAPA1,ASPHD1,SYT13,APC,CHRD,LDLRAD4,TAOK2,STOML1,QKI,CPS1,CSF1,CSF1R,RIMS2,RASSF2,RASGRP2,CORO2B,FHL1,TPK1,SIGLEC8,GNAO1,GRB10,GRM8,KCNN1,LIFR,ADAM22,MX1,PDE4B,ENPP2,SLC25A23,STRN3,NECAB2,FSD1,PPARA,TCP11L1,RPS6KA2,EMID1,SH3BP2,FRMPD1,SLC2A5,SLC11A1,ERC1,TACR1,MCF2L,TRO,SPHK2,DNALI1,HPS4" Drug 4261_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADCY6,MTUS1,APC,SHROOM2,CDK10,SEMA4G,ST3GAL5,SCARB1,RAB26,CREM,SLITRK5,DBT,KIAA0753,PLPPR4,SGSM2,FCF1,FAM13A,ETV1,FGFR1,ANKFY1,TRMO,DENND2A,GLI2,GLYR1,CNTRL,FAM69A,JAK2,TAGLN3,NDP,CLDN11,PIK3R1,CCSER2,RETREG1,MAPK9,GRAMD1C,ZSCAN32,TMEM231,FBXW7,SUPT20H,FNDC3A,SMARCD3,SPTAN1,ARHGEF9,IQCE,SSBP2,WIPF1,EMSY" Drug 6311_DN Clebopride maleate [84370-95-6]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "AMT,CDC42BPA,APC,C5,CA12,SEPT7,FOXN3,ARMC8,NRG2,CNTNAP2,DPH1,RCAN1,OPTN,ING4,ERCC2,CDKL3,BAIAP2,CINP,OGA,FYN,B4GALNT1,ERAP1,DISC1,GPR37,BACH2,MAPT,MEIS1,TAGLN3,ZNF862,NFYA,SLC11A2,PLCD1,FSD1,PPP5C,ZDHHC14,GAL3ST4,RPS6KA2,SAFB,ASAP3,NLGN1,IFT122,NXT2,SEPT8,TCF4,SYNE1,ZNF34,URM1" Drug 4950_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ASIC1,NDRG2,ADRA1D,AGT,AK2,CDK13,ALDH7A1,ADAM23,SGCE,BAIAP3,KALRN,HOMER3,PCYT1B,RCHY1,CRMP1,CSF1,RIMS2,MFAP3L,NRN1,ZNF589,OLFM1,AGAP2,OGA,GAD1,GLYR1,GNAL,LPAR4,SYNPO,P2RY1,MINDY2,RGS12,KCTD17,KLHDC8A,PNMA8A,RPS6KA2,KCNIP1,CNKSR2,ZNF423,ZBTB43,ATP10B,PHLDB1,PLCB1,PARD3,TRIO,ZNF711,SPHK2,GDPD5" Drug 5522_UP Phensuximide [86-34-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ABR,ADCY6,ADD2,LTBP4,CDK10,CDK13,AZGP1,GYG2,SGCE,CAMK2B,CDO1,QKI,CRMP1,RIMS2,HS3ST2,DTNA,TNK2,MTSS1L,TMEM8B,POLL,PCLO,KCNB1,KHK,KIF5A,KPNA5,KITLG,ADAM22,NF1,PCBP3,NTRK3,PLCD1,PLXNB1,PPP2R2B,GDPD2,ELMO2,ZC3H13,SYN2,SYP,EXOC7,KIAA1107,TNS2,TNS1,UBTF,PLPPR2,ZNF24,NT5M,SLC17A7" Drug 4007_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.40E-07 3.24E-02 4.21E-05 4.74E-04 47 199 "ADD2,APAF1,MADD,BCHE,CFLAR,FUBP1,HAP1,CBS,SCARB1,PLEKHB1,CNTFR,AKAP5,ENTPD4,CRY2,EDIL3,ETV1,FGF14,PDLIM5,PRELID3A,SPACA9,TJAP1,IL12A,KIT,NPR2,NTRK2,NLE1,PLCD1,CNNM2,PTPRN2,C1orf54,SUSD4,GAL3ST4,RGS4,GSTCD,STUM,ZHX3,ZNF423,PHLDB1,COBL,EXOC7,ADGRL3,SLC44A1,R3HDM1,TNS1,SSBP2,UCHL1,ZNF24" Drug CID000005657 NSC7524 Stitch 8.38E-07 3.67E-02 4.75E-05 5.36E-04 44 182 "ASIC1,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ATP1A1,ATP1A3,ATP1B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CBS,CCK,CACNA2D2,ASIC3,CHRNA4,DBI,DMPK,PTK2B,MSTN,GRIK4,GRIK5,GRIN2C,GRIN2D,CIT,NPY,PDE1C,PDE1B,ENPP2,PKD1,RYR3,SCN7A,SLC6A11,SST,SYN1,SYN2,TACR1,ST8SIA2" Drug 3559_UP Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.50E-07 3.73E-02 4.75E-05 5.36E-04 45 188 "RALGAPA1,C1QTNF1,APAF1,KCNAB2,RGS20,CFLAR,CACNA1G,CAST,SLIT2,QKI,RCHY1,CNTNAP2,FAM169A,GREB1,GPRASP1,TMCC2,RCAN1,EGFR,ERCC2,F5,DLC1,AFF2,GAD1,ERAP1,TMEM8B,SESN1,GPER1,KCNH2,MAP2,MMP16,NF1,OXTR,PDE1C,RPS6KA2,SYBU,FAM214B,LIMCH1,SPTAN1,RGL1,PLCB1,ASTN2,REEP1,EVI5,SLC17A7,KCNAB1" Drug 5596_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.50E-07 3.73E-02 4.75E-05 5.36E-04 45 188 "SYN3,AMT,APAF1,CDK13,DNAH17,CFLAR,LDLRAD4,CAMK2B,CBFA2T2,ASIC3,CSF1R,VCAN,CNTNAP2,CTH,RASSF2,HIPK3,MBNL2,PLXNC1,ING4,C3orf18,MTSS1L,EPHB1,CORO2B,TMEM8B,STON1,HAS2,TJAP1,KCNJ5,LMO2,MSR1,LYRM9,CNOT4,NTRK2,SERPINI1,PTN,TCP11L1,CPEB3,KDM4B,KDM4C,SPTB,ATP10B,ZEB1,DNAH7,R3HDM1,LAT2" Drug 222_DN "LY-171,883; Down 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Down 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "ASIC1,NDRG2,ADD2,ALK,MYRF,CA12,CHN2,SLIT2,CLIP3,AATK,JAKMIP2,DMPK,DYNC1I1,EDNRA,CALCRL,ETV1,ANKMY1,PTK2B,ZMYND10,FGFR1,FHL1,FYB1,DISC1,RUNDC3A,GLI2,GNAL,GNAO1,GRB10,GUCY1A1,NXPH3,NF1,NTRK3,FXYD1,PPP5C,MAPK3,C1orf54,HUNK,FERMT1,PPP4R3A,HECW1,ZC3H13,SPART,PRRC2C,COBL,ADGRL3,GPR161" Drug 2764_UP Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "NDRG2,OSBPL1A,NME5,PPFIA3,MARK4,ATP2A2,ATP2B2,SYNJ1,ST3GAL5,SYNJ2,SCAPER,CACNA1I,HAP1,ARHGEF1,HOMER3,CSNK1E,DOCK4,DAPK3,PARD6A,CDON,FAM198B,ACSL4,DLC1,SCARA3,KHDRBS3,IL6R,KCNB1,MAPT,MYO7A,NF1,MTRF1L,ZDHHC14,GTDC1,RGS3,FAM192A,SBF1,ZNF821,RASA3,FBXO11,PKNOX2,CAMTA2,SYNE1,HEY1,PDIA2,EPM2A,KAT6A" Drug 6835_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "ASIC1,AMH,AMPD3,AMPH,AMT,MARK4,N4BP2L1,ADAM23,CFAP410,CA4,CACNA1A,ENTPD2,CNTN1,NRG2,CDC42BPB,CRMP1,ABCG1,PDE4DIP,MAML1,RUSC2,DMPK,OPTN,CELSR3,ELN,MTSS1L,ERCC2,BAIAP2,FYB1,SEPT9,SRCAP,AHDC1,IL6R,ADAM22,ZNF862,SUGCT,S100B,SCN2B,SH3BP2,FAM214B,TSPYL2,SYT5,TBL1X,SZT2,FLRT2,NT5M,KAT6A" Drug 4424_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "ALCAM,AMPD3,GAS7,PDE8B,MARK4,LDLRAD4,CA4,HAP1,CAMK2B,CLGN,CRLF1,SIPA1L1,RIMS2,SEC14L5,RUSC2,SLC12A6,ING4,DLC1,KHDRBS3,SRCAP,GFER,GNAL,PCLO,HSF2,KCNN1,KCNQ3,MIA2,ADAM22,MYT1,NF1,MTRF1L,PPARA,MAPK7,MAPK10,KCNIP1,FAM214B,KDM4B,PDZD2,ARC,TK2,PIK3R5,HIRA,PLPPR2,VIPR2,EMSY,EPM2A" Drug 6555_DN Prostaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "AMT,APOC1,PPFIA3,RGS20,ARRB2,MARCH3,MPDZ,CLCN3,NCOR2,AATK,CNTNAP2,SPOCK3,RCAN1,FCF1,CNNM1,ZNF589,FGFR1,PDLIM5,CSPG5,TRAF3IP2,B4GALNT1,GCNT2,ARFIP1,HNMT,IL6ST,MT1M,NFIX,NPR2,PPP5C,PTPRN2,RPS6KA2,RXRA,SH3BP2,FNDC3A,DOP1A,TROVE2,THSD1,SS18,JMJD6,COBL,ASTN2,ZNF34,MAP3K12,UBE3B,KAT6A,RNF146" Drug 6081_DN Avermectin B1 [71751-41-2]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "ABHD6,ALCAM,BIN1,BCAS1,CDK13,MARK4,SYNJ1,FUBP1,MTMR3,CACNA1I,CAMK2B,CBFA2T2,SRSF11,VAX2,CRY2,SOCS5,DAPK3,TMCC2,DTNA,ING4,MRNIP,NCALD,FECH,RAB30,GPR37,CACFD1,ELOVL5,HNMT,INPP5B,KPNA5,MAP4,MATK,MID1,PPP2R2B,MAPK7,ZNF821,FAM214B,BTBD7,ARHGAP26,TROVE2,ELOVL4,SYN2,TACC1,EXOC7,SLC44A1,WIPF1" Drug 5752_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.59E-07 3.76E-02 4.75E-05 5.36E-04 46 194 "ADD2,N4BP2L1,SYNJ1,GYG2,PLEKHB1,TPP1,AKAP12,CRMP1,ABCG1,DTNA,ECM2,EGFR,PLXNC1,ING4,FGFR1,HPCAL4,SEMA4D,ZNF44,SRCAP,COPS8,GNAO1,SPACA9,ADAMTS6,KIT,ADAM22,PDE4D,PPP5C,MAPK10,PTN,ZSCAN32,ACSS3,NEK11,TCP11L1,SEMA6D,SUPT20H,NLGN1,PPP4R3A,SLC11A1,FAIM2,RBM34,SPTB,IQSEC2,SYN2,MCF2L,SLC30A3,NT5M" Drug 2520_UP Tetrandrine [518-34-3]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "MTUS1,C1QTNF3,ALK,CDC42BPA,APAF1,PPP4R4,SYNJ1,LDLRAD4,HIP1R,SCARB1,SYNGR3,SOCS6,CREM,DZIP3,HS3ST2,SLC12A6,HIPK3,C3orf18,SIGLEC8,ALDH1L1,PCDH17,ATXN2L,HMGCR,IL6ST,KCNN1,LSS,MEF2C,ADAM22,SLC11A2,NRCAM,PFKFB4,CCSER2,PPP5C,GAL3ST4,ZFHX4,SEMA6D,SH3BP2,PREX2,SLC11A1,PEG10,DNMBP,RPGRIP1L,SLC19A3,TLR4,XRCC4,EVI5,PHTF2" Drug 6766_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "C1QTNF3,AMPD3,DNAH17,CFLAR,CACNA1I,BAIAP3,CA4,CD86,ARHGEF1,GREB1,DCAF4,SNPH,DBN1,ZNF804A,DUSP9,PLXNC1,FGF13,FGFR3,HPCAL4,ERAP1,TDRKH,STON1,GRIK5,CACFD1,DHX35,KCND1,MAP4,MAPT,MEIS1,MIA2,AFDN,MMP16,TAGLN3,OPRL1,PDE1C,PFKFB2,LRP12,RELN,SH3BP2,SNCA,IQSEC2,TSPYL2,PHLDB1,WSCD1,CUX2,TK2,TRPM2" Drug 3907_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "NDRG2,BIN1,KCNAB2,CDK13,MARK4,SLC4A4,CA4,CAMK2B,VAX2,WHRN,SLC12A6,DTNA,HIPK3,EGFR,MRNIP,ERCC2,FER,FHL1,TRMO,SRCAP,RUNDC3A,GLYR1,LIG4,MAP2,MMP17,NEK1,NF1,OGG1,PRKCB,PTK2,CEP97,MSANTD2,RGS12,SBF1,SLC9A5,BTBD7,SMARCD3,ARHGAP26,KIAA0930,AP4E1,ZNF34,THRA,TK2,ZNF24,ITM2C,UBE3B,SENP7" Drug 2788_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "KIAA1324,DDO,BCAS1,PLA2G4C,ARSE,DNAH17,RASL11B,SLC4A4,CACNA1I,ARHGAP33,ASIC3,TAOK2,RIMS2,FRY,CELSR3,SPEG,ZNF589,DLL3,FYB1,SIGLEC8,DISC1,GFER,HPGDS,ELOVL5,TJAP1,KCNQ3,MGAT3,ZNF862,NELL2,PDE1C,ELOVL2,RGS12,RPS6KA2,KDM4B,TSNAXIP1,HECW1,ATP10B,SYN1,PCDHGA10,CABIN1,UGT8,WIPF1,REEP1,KCNAB1,PARP11,RNF170,DPF3" Drug 3081_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "ABHD6,DNAH17,MPDZ,BCL7A,CACNB4,EPS15L1,RAB26,HOMER3,FAM149A,NCOR2,ABCG1,AATK,SLITRK5,KLHL3,SPOCK3,TMCC2,EDIL3,SEZ6L2,CELSR3,C3orf18,DLC1,ZNF44,HPGDS,PRUNE2,PCLO,KIT,MEF2C,AFDN,TAGLN3,MYO6,SLC11A2,PURG,LRRN3,MAPK3,MARCH1,RASGRF1,ZDHHC14,ZFHX4,BAALC,ZC3H13,TK2,TNS1,TUBB1,VIPR2,CLIP2,MAP3K12,KCNAB1" Drug 3882_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "BIN1,APAF1,APC,APOC1,CDC14B,PRX,PPP4R4,ADAM23,KSR1,CFAP410,CALB1,CAMK2B,FOXN3,WHRN,COL9A3,DCAF4,SNPH,SPOCK2,BRINP1,MFAP3L,RUSC2,EPHB1,SPEG,CORO2B,DLC1,FGFR3,BAIAP2,OGA,GLYR1,GNAO1,GNG4,ITPKA,KCNN2,LSS,MEF2C,AFDN,PDE1C,RETREG1,MAPK7,SH3BP2,CPEB3,THSD1,DICER1,TMPO,TPM2,UBE3A,SPHK2" Drug 3968_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "C1QTNF1,LTBP4,BIN1,RUNX1T1,KYAT1,STOML1,WHRN,CRY2,NCOR2,AATK,CSF1,VCAN,HEPH,RCAN1,EDIL3,RASGRP2,RASL12,F5,ALDH1L1,PCDH17,ICA1,LSS,MARK1,MMP16,NCF2,NTRK2,ENPP2,NECAB2,DIRAS2,CNTLN,MARCH1,PNMA8A,ZFP2,STUM,SH3BP2,CNKSR2,ARHGAP26,JMJD6,PCDHGA10,DOCK9,R3HDM1,TNS1,OSBP2,CLIP2,LAT2,KCNAB1,PCBP4" Drug 5601_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "NDRG2,AGT,APC,KSR1,BAIAP3,CAMK2B,CHN2,WHRN,CSF1R,GREB1,RASSF2,SPOCK2,EGFR,EGR3,DCTN2,PDLIM5,GABRG2,PCLO,SPACA9,GRM8,ATXN2L,KCNJ5,KCNN1,AFDN,MMP16,ADAM22,PDE1C,LRP12,DCHS2,ELOVL2,KLHDC8A,CPEB3,SYBU,UNC5B,ATP10B,SAMSN1,ARC,TAL1,ADGRL3,TCF4,ZEB1,UCHL1,WIPF1,XRCC4,MKRN3,KCNAB1,FAM13C" Drug 2148_UP Boldine [476-70-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "MTUS1,BIN1,APAF1,ARNTL,ATP6V0A1,SLC16A4,SEPT7,CLGN,SOCS6,SULT4A1,CNTFR,CREM,CRMP1,PDE4DIP,TMCC2,SHANK1,EIF1,PDLIM5,CAMKK2,ERAP1,ALDH1L1,SRCAP,RUNDC3A,ZNF276,GRIK5,AP4S1,PADI2,IL12A,ITPKA,ZNF862,SETD4,LRP12,PPP5C,BCAS3,PTPRN2,SLC9A5,RBM34,SPTAN1,CDK19,SEPT8,CEP68,TBCEL,CDK20,ZFP37,SPHK2,TFIP11,TIGD6" Drug 3276_DN Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "ALK,GAS7,FAM131A,APOC1,BCAS1,ARRB1,CFLAR,CA4,LHX2,NECTIN3,GREB1,DCAF4,DAPK3,TOM1,EDNRA,COQ7,PRELID3A,DISC1,TJAP1,INPP5B,KIF2A,MAP4,TM6SF1,GIT1,ADAM22,NPR2,RETREG1,RGS12,RNASEL,RPS6KA2,KCNIP1,SBF1,RASA3,ANKRD6,SIRT2,BTBD7,CLASP2,CLSTN2,PLCB1,SLC44A1,TRIO,PLPPR2,VAV1,WIPF1,KCNAB1,EPM2A,ST7" Drug 3840_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "NDRG2,ADORA1,AGT,ALK,TRMT9B,KCNAB2,SEMA4G,CACNA1I,CFAP410,CBFA2T2,CPS1,IPCEF1,RASSF2,KIAA0319,TMCC2,DTNB,EDN1,AGAP2,SRCAP,HLF,ELOVL5,KCNJ5,NPY,PCDH8,TMOD2,PLTP,PTCH1,PTPRD,PTPRH,KCNIP1,CPEB3,PKNOX2,SLC9A5,LIMCH1,RBM34,KDM4B,TSNAXIP1,ARHGAP26,SPART,SSTR2,ARC,TK2,UCHL1,PDIA2,FLRT2,VGF,LMF1" Drug 3689_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "ADCY6,ADRA1D,NME5,ATP6V0A1,ADAM23,ADGRB2,CACNA1I,FOXN3,CHN2,LHX2,EPS15L1,LRIG1,SUSD5,PDE4DIP,CNTNAP2,PYGO1,CDKL3,KAT8,HPCAL4,SEMA4D,DCTN2,POLL,ITGA7,KCND1,KCNN1,ADAM22,ZNF862,NRCAM,TREM2,SMIM7,LRRN3,MAPK7,SUSD4,RASGRF1,SALL1,CPEB3,NLGN1,NFASC,DOCK9,OBSL1,CRTC1,PCDHA5,UCHL1,VAV1,VIPR2,SPHK2,EPM2A" Drug 1474_UP Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "C1QTNF3,AMPD3,APLP1,DNAH17,SLC4A4,CFLAR,ST3GAL5,SCAPER,GYG2,CACNA1I,ARHGAP33,SULT4A1,WHRN,ARHGEF10,DAPK3,MFAP3L,FGFR1,IQCG,ALDH1L1,GLYR1,GRIK5,HNMT,LSS,MAN2A2,MSI1,MYO7A,NELL2,PCBP3,CLDN11,RETREG1,LRRN3,RELN,TMEM255A,ZDHHC14,SLC2A5,ARHGAP26,SPTAN1,MCF2L,IQCE,SYNE1,CRTC1,HIF3A,CHST8,WIPF1,KCNK12,SLC30A3,KCNAB1" Drug 6038_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.62E-07 3.78E-02 4.75E-05 5.36E-04 47 200 "AMPD3,AMT,CDC14B,MARK4,ADAM23,SNPH,RUSC2,DTNB,HSD17B14,ERBB2,AFF2,FUT9,ZNF44,DISC1,ALDH1L1,GFER,GRM8,SOX21,ICA1,C2orf72,TJAP1,IL6ST,KCNN1,MYT1,PCDH9,LRRN3,MAPK7,MAPK10,PSD,SNRK,CNTLN,CCDC40,RASGRF1,KHDRBS2,RFX2,RGS12,DZIP1,PKNOX2,SLC11A1,ZSWIM8,ST5,TACR1,TBCEL,ZEB1,TPM2,TRO,XRCC4" Drug ctd:D010278 Parathion CTD 8.64E-07 3.79E-02 4.76E-05 5.36E-04 139 822 "ACHE,ADCY8,FZD9,ADRB2,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,LGR5,CDK10,ZNF583,KIF1A,ADAM23,BCHE,NRP2,CCK,CD38,LARGE1,ZNF445,UBE2L6,NGEF,LY86,MYRIP,NRG2,CRMP1,CNTNAP2,ERC2,ARMCX2,SV2B,HS3ST2,EGFR,RGS17,ZNF549,NRN1,ZNF585B,FGF12,AFF2,HHIPL1,FYB1,MEGF10,GAD1,ZNF559,SYT17,NTNG2,LNX1,MCHR1,GRIN2C,GRM2,PTPRT,GSTM5,GSTT2,SOX21,PADI2,FRMD5,HLF,ZNF491,USP51,IRF8,KIT,LAMA2,LIG4,MATK,MATN3,MBP,CHST6,MN1,MYCN,FXYD7,NEFM,NEFH,NPTX2,NTRK3,CYTL1,ABCB1,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RASGRF1,BEND5,KHDRBS2,RET,FIGN,ZDHHC4,ZNF671,HUNK,CCDC112,SALL1,SCP2,HES6,SEC14L1,GALNT10,FERMT1,ST6GAL1,DZIP1,ELMO2,INAVA,SNRPN,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,SYP,ASTN2,PCDHGB7,NAT16,TMEM121,TIMP4,PRRT1,IL34,CHST5,TRIO,RUNDC3B,FLRT2,VLDLR,KCNK12,ZIC1,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PLD4,DNAH10,NETO1" Drug 4444_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.14E-07 4.00E-02 5.02E-05 5.66E-04 41 165 "ADRB2,EPB41L5,ARNTL,ST3GAL5,SYNGR3,CHN2,NRXN3,ABCG1,PDE4DIP,CTH,JAKMIP2,C2CD2L,PLPPR4,RGS17,TAOK3,BAIAP2,FYN,CYP46A1,GUCY1B1,FAM69A,ITGA7,KCNH2,LIFR,MAP2,MMP16,PCDH9,SERPINI1,PRPH,ACSS3,ENOX1,RGS4,SH3GL3,KDM4B,DOP1A,THSD1,ELOVL4,CEP68,RGL1,SYT1,SSBP2,SLC30A3" Drug 7535_DN irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.43E-07 4.13E-02 5.18E-05 5.83E-04 42 171 "MAP4K3,CDK13,NCOA1,ARHGEF7,KRIT1,OSBPL3,SIPA1L1,PUM1,KIAA0586,MBNL2,GPHN,TAOK3,CHST15,SEC24B,SYNCRIP,MBP,MEF2C,MEIS2,MID1,PDE1C,CCSER2,REV3L,ZFHX4,ATXN2,SCAF8,CHD9,EPN2,ATF7IP,KDM4B,ERC1,ERBIN,ANKRD12,MTCL1,TCF4,ZEB1,TCF12,TIAM1,PARD3,KAT6B,TRIO,TRPS1,UBE3A" Drug 1072_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 9.66E-07 4.23E-02 5.30E-05 5.97E-04 43 177 "ARNTL,ST3GAL5,CBFA2T2,AKAP12,CTH,RUBCN,TSPAN5,OPTN,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,FYN,CYP46A1,RAB40B,RNFT2,PADI2,MITF,MXI1,NEK1,PCDH9,SERPINI1,PRPH,PTPN13,SGK1,SH3BGR,SH3GL3,PPM1E,WDR47,KDM4B,ZBTB43,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,REEP1,SLC17A7" Drug ctd:C029938 nickel sulfate CTD 9.80E-07 4.29E-02 5.35E-05 6.02E-04 244 1610 "NDRG2,TMCC3,RNF157,ADORA2A,ZNF608,INTS2,MTUS1,ALCAM,AMPD3,BIN1,SEMA7A,APBA2,DDO,CDK10,CASK,ARRB1,ASGR1,STK33,ZBTB10,SLC4A4,ATP1B3,DPY19L3,DOCK11,BACH1,RGS9,NRP2,BID,CFLAR,C5,DDR1,USP2,CD86,ENTPD6,DGKI,CDC25B,MAGI1,CDO1,MS4A7,SLIT2,LHX2,CLTB,IQCK,COL4A5,ABI3BP,ZNF385A,FAM171B,CREM,IPCEF1,VCAN,PDE4DIP,CTH,RUBCN,MYADM,DAPK1,ARMCX4,ARMCX2,LYPD1,RHOBTB1,SACS,CHRDL1,DLX1,DNAH9,SLC29A4,RCAN1,TOM1,MAMLD1,DNAJB6,EDIL3,EDN1,CNNM1,RASGRP1,FRY,EBI3,EGFR,AASS,EIF4G1,PLEKHA1,PCOLCE2,ELN,CALCRL,ENO2,GPHN,RAB9B,EYA1,ARMCX1,ZNF585B,CORO2B,ST3GAL6,CHST15,FECH,FGF1,SEC23B,FOXF2,SEMA4D,FLNC,FLT1,SLC37A3,NOP56,TRIM16,FYN,GAD1,GALC,B4GALNT1,IQGAP2,GATM,GCNT2,AHDC1,GFRA2,PPARGC1A,GLUL,DCLK2,GNAL,LILRB4,PRUNE2,GPER1,C1QL4,SERP2,GSN,HBA1,FRMD5,FRMD3,AGBL5,NEGR1,CPT1C,IRF8,IDH3B,IFI16,SHISAL1,RBPJ,IL12A,INSM1,ITGA7,KIT,LIFR,NCOA7,MAPT,MATN3,MEF2C,MEIS2,MEST,KITLG,MID1,MITF,MMP16,MX1,NCF2,NFE2L2,ALDH1L2,NOVA1,NPR2,CLDN11,DPY19L2P2,PRTG,PDE3A,PDE4B,PDE4D,SLC10A4,TMOD2,PFKFB3,SNX10,RETREG1,KCTD15,PLEC,PLTP,LRP12,RETREG2,PILRA,PRKAB2,MAPK3,EPDR1,MAPK9,GRAMD1C,DEF8,ELOVL2,PTPRB,PTPRG,TTC13,ZNF844,TMEM255A,RAP1GDS1,GAL3ST4,ZFHX4,FBXW7,STX1B,AP1AR,S100B,SEMA6D,SATB1,SGK1,KIF16B,CPEB3,FNDC3A,ANKRD6,FAM81A,BTBD3,ZNF334,NAPB,SNCA,PDZD2,KDM3A,SPP1,PEG10,ZC3H13,MCF2L2,NFASC,ITPRID2,SAMSN1,ZC4H2,RGL1,SULF2,NSFL1C,JMJD6,AGTPBP1,TCF4,SATB2,ZEB1,ARL10,TIAM1,TLR4,BEX4,TNS1,NPL,TRO,SSBP2,ZNF610,PLEKHH2,VLDLR,WIPF1,CLIP2,RICTOR,ZIC2,LYPD6,ZNF154,ZNF184,DNALI1,STOX2,NAV3,TRIM16L,PLSCR4,FZD3,ADAMTSL3,SNX14,IFT88,GAN" Drug 5764_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.83E-07 4.31E-02 5.35E-05 6.02E-04 44 183 "AMH,APBB2,APC,GAS7,KIF1A,BMP7,IL33,PLEKHB1,WHRN,CREM,AKAP12,CRMP1,PHF14,CTH,PITPNC1,CDKL3,PTK2B,SYT17,GDF9,GRM2,ATXN2L,ITPKA,KCNN1,NPY,PDE4B,PDE4D,SMOX,PMP22,FA2H,LRRN3,PPP5C,PID1,RBBP6,RGS4,NLGN1,PPP4R3A,IQSEC2,TBCEL,DNAH7,R3HDM1,CHST5,TUBB1,VAV1,GAN" Drug 2672_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 9.95E-07 4.36E-02 5.35E-05 6.02E-04 45 189 "C3orf14,MTUS1,APBB2,DNAH17,HIP1R,CLGN,COL9A3,SIPA1L1,DZIP3,PPP1R16B,DOCK4,ZNF337,GSDME,PARD6A,MBNL2,SRPK3,TLR7,TBC1D16,FER,PDLIM5,ADAM28,GNAO1,STON1,PCLO,IFI16,MEF2C,PCDH9,SERPINI1,SLC25A23,LRRN3,MAPK7,EMID1,ZNF415,CDK19,RGL1,STXBP1,PJA1,HEY1,TRO,TRPS1,SSBP2,SLC17A7,FZD3,PHTF2,JPH3" Drug 2880_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "AMT,SEMA4G,ARHGDIG,SLC4A4,SYNJ2,ASIC3,PLAA,QKI,ABI3BP,ABCG1,PHF14,GREB1,DCAF8,MFAP3L,SLC12A6,CNNM1,VPS13B,FGFR1,IQCG,PDLIM5,MALT1,RAB30,MSL3,GNG4,JAK2,MBD1,NF1,NPR2,CCSER2,PLCD1,MBOAT7,PPP5C,CNNM2,RGS12,CLIP1,ZFP30,SH3BP2,SOX3,CDK19,TROVE2,CAMTA2,CRTC1,CHST8,TMPO,PLPPR2,DNALI1" Drug 6667_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ADD2,TRMT9B,APAF1,APC,GAS7,ADAM23,LDLRAD4,PLEKHB1,ABCG2,RAB26,WHRN,ABCG1,RUSC2,CDON,CELSR3,VPS26C,FAM49B,FYB1,GNG4,LPAR4,CNTRL,SYNPO,INPP5B,MAPT,TM6SF1,MEIS1,CNOT4,NOVA1,PLXNB1,MAPK7,GRAMD1C,SUGCT,GSTCD,KIRREL1,SCN8A,TSNAXIP1,IQSEC2,TROVE2,ASTN2,KIAA1107,DNAH7,TIAM1,TRIO,XRCC4,TFIP11,NT5M" Drug 4291_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ASIC1,ADGRF5,APC,SEMA4G,PPP4R4,NRP2,CAMK2B,ASIC3,TAOK2,HAPLN1,FAM131B,TM9SF4,GIT2,ARMCX2,RUSC2,SUGP2,EGFR,IRAK4,ING4,CDKL3,PTK2B,FGFR1,SESN1,POLL,SOX21,SHISAL1,ADAM22,NF1,PALM,PLXNB1,RIPOR1,ACSS3,SAFB,PREX2,ZHX3,SPTB,TROVE2,SAMSN1,SS18,KIAA1107,TNS2,CRTC1,GPR161,SEMA3B,URM1,SENP7" Drug 2500_UP Nystatine [1400-61-9]; Up 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "BEGAIN,PKP4,SEMA4G,RASL11B,NRP2,MTMR3,CFAP410,CALB1,SLC16A4,SEPT7,CDO1,EPS15L1,CRMP1,PDE4DIP,DCAF4,SNPH,MAMLD1,HEYL,RASGRP2,FER,PDLIM5,CAMKK2,GPD2,NCKAP1L,ITPKA,AFDN,MPP2,NNAT,NTRK2,PIK3R1,PMP22,RELN,RFX2,PNMA8A,HSPA4L,FERMT1,SNCA,SPP1,ZC3H13,SPTB,PHLDB1,GPR161,TK2,CDK20,VIPR2,MKRN3" Drug 6558_UP 5194442; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "DOC2A,BIN1,AMT,CFLAR,BMP7,GYG2,CFAP410,CA4,CCNT1,CHRNA4,TAOK2,LHX2,SH2B1,CSF1R,CTH,DBT,CNNM1,COQ7,KAT8,AGAP2,ATP2C1,GFER,GNG4,GRB10,ATXN2L,TJAP1,MXI1,NFYA,PCDH9,LRP12,RGS12,KCNIP1,ASAP3,SPTAN1,ANKRD12,EXOC7,CRTC1,CHST8,TK2,RUNDC3B,RPRM,FAM155A,KLC2,ZBTB14,ZNF189,EMSY" Drug 3901_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ASIC1,ALK,AMPD3,CACNA1I,CACNA2D1,WHRN,SEC14L5,HEPH,SHANK1,SRPK3,ELN,VPS13B,DLC1,FGFR1,CAMKK2,GFER,GNAO1,GRIK5,SOX21,ITPKA,KCNJ5,KCNN1,KCNN2,KIFC3,MARK1,NELL2,NNAT,CNOT4,PIK3R1,LRP12,NECAB2,MINDY2,PTCH1,ELOVL2,ZSCAN32,TRIM68,RGS12,RPS6KA2,CPEB3,SLC2A5,LIMS2,SNCA,KDM4B,CLSTN2,PLCB1,HIRA" Drug 5229_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "AGT,NME5,KIAA1324,ALCAM,ALK,SEMA7A,APBB2,MARK4,CFLAR,HAP1,ARHGAP33,CLGN,SOCS6,NCOR2,VCAN,CTH,CDON,HIPK3,MBNL2,C3orf18,FGFR1,AGAP2,TPK1,RUNDC3A,GLYR1,POLL,CNTRL,GRIK5,KPNA5,ZNF862,OGG1,PDE4B,PLCD1,TCP11L1,SH3BP2,FAIM2,ATP10B,NXT2,WSCD1,R3HDM1,CDK20,TRIO,TRPM2,UCHL1,SLC17A7,EPM2A" Drug 6821_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ABHD6,NDRG2,ADCY6,CDC42BPA,BCAS1,MARK4,TAOK2,ARMC8,CTH,ARHGAP32,EXOG,SLC12A6,EDNRA,TNK2,SCML2,SEMA4D,SMC2,MALT1,GLYR1,GNG4,INPP5B,ITPKB,KCNH2,MAP4,MAPT,MBD1,KITLG,MPP2,NF1,FSD1,PRPH,APTX,PTPN13,RGS3,RGS12,RNASEL,RPS6KA2,SH3BP2,ZHX3,SP2,TSPYL2,ARC,PARD3,EMSY,EVI5,SEMA3B" Drug 5474_UP Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "RALGAPA1,ADD2,ADORA1,ALK,PDE8B,MARK4,CFLAR,LDLRAD4,USP2,HOMER3,RCHY1,CSF1,SLC12A6,MBNL2,EGR3,TNK2,STX2,EZH1,F5,CORO2B,DCTN2,ZNF44,SRCAP,GUCY1B1,C2orf72,LIG4,MAN2A2,NFYA,LRP12,GAL3ST4,MRAS,ASAP3,PEG10,CLASP2,CLSTN2,RGL1,JMJD6,EXOC7,KIAA0930,RPGRIP1L,PCDHGA10,TK2,KCNK12,NT5M,DNALI1,KCNAB1" Drug 1785_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "APAF1,WASF1,LDLRAD4,HIP1R,RUNX1T1,LRBA,RAB26,AATK,OSBPL3,PDE4DIP,DOCK4,C2CD2L,GSDME,DTNA,ANKRD46,FAM13A,MBNL2,MRNIP,ACSL4,KAT8,PTPRT,ACOT7,IDH3A,MEF2C,SLC11A2,NTRK3,GPSM2,PRKACB,MAPK10,DEF8,PTK2,RAD51D,RGS12,SATB1,PPM1E,SPART,SS18,MCF2L,TBL1X,TCF4,UCHL1,FLRT2,TRIM9,GDPD5,ST7,SMIM8" Drug 6299_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ASPHD1,PPFIA3,PPP4R4,FUBP1,SCAPER,MYRF,RUNX1T1,SCARB1,ARHGEF2,ABCG1,ARHGEF10,PDE4DIP,SV2B,DTNA,TOM1,DUSP9,EDIL3,MRNIP,COQ7,IGSF6,RRAGB,DENND2A,TMEM8B,IL6ST,LIG4,NOVA1,NPR2,CLDN11,POLG,CNTLN,PTPRN2,TCP11L1,SUPT20H,ZFP30,DZIP1,KDM4B,ZHX3,PHLDB1,ARHGEF9,CHST8,TIAM1,TK2,TPM2,HIRA,TRIM9,SEMA3B" Drug 4148_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "LTBP4,BIN1,APOC1,CDK13,ADAM23,CFLAR,SYNJ2,RUNX1T1,USP2,RAB33A,STOML1,DBT,DMPK,SNX29,EDN1,EDNRA,CORO2B,FHL1,NSG1,ZNF44,GLI2,GRIK5,ICA1,KCNJ5,MAP4,MID1,ZNF862,NTRK3,PLTP,PPP5C,C1orf54,RGS12,RNASE1,ASAP3,SLC11A1,LIMCH1,PDZD2,SP4,PEG10,PHLDB1,TACR1,R3HDM1,TRIO,AMACR,CLIP2,SLC30A3" Drug 5229_DN troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ABHD6,LTBP4,CDC42BPA,SEMA4G,ARRB1,GYG2,CACNA1I,KYAT1,CCNT1,CRLF1,PLEKHB1,SLIT2,VAX2,PPP6R2,GPRASP1,MAML1,ENO2,POMT1,PRELID3A,USP19,TDRKH,ELOVL5,INPP5B,MID1,MITF,MMP16,SMIM7,FSD1,PRKAR1B,TMEM104,WDR25,FAM184A,TCP11L1,SH3BP2,ASAP3,SYBU,SMARCC2,ZHX3,THSD1,TMEM121,CABIN1,TRIO,VGF,VIPR2,REEP1,PCBP4" Drug 5783_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ABHD6,CDC14B,C5,ARHGEF1,SCARB1,AKAP7,HAPLN1,MRNIP,RGS17,DENND4A,CDKL3,FGF13,FGFR1,SRCAP,MSL3,GPR37,SHISAL1,INPP5B,GIT1,NF1,PIK3R1,PLCD1,MAPK7,TMEM231,RAD51D,NEK11,NCBP3,ASAP3,AMBRA1,ST6GAL1,BTBD7,TMCC1,LHPP,JMJD6,PDLIM2,WSCD1,TNS2,CHST8,THRA,TNS1,FAM155A,KLC2,XRCC4,NT5M,MPPE1,UBE3B" Drug 3508_DN Risperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ABHD6,AP2A2,AK2,BEGAIN,DOC2A,PPP4R4,PDE8B,MARK4,RASL11B,KIF1A,ABI3BP,GREB1,JAKMIP2,EIF5,ING4,VPS13B,STX2,ACSL4,FGFR1,BAIAP2,PRKAG2,FHL1,CINP,PRELID3A,OGA,GAD1,TDRKH,SPACA9,HNMT,NF1,CNOT4,NPTX1,OGG1,RETREG1,ZCWPW1,GSTCD,CCDC25,EMID1,SEMA6D,FNDC3A,POGZ,ZEB1,AP4E1,CABIN1,ZKSCAN5,SEMA3B" Drug 6180_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "ADD2,ADRA1D,MTUS1,AGT,C1QTNF3,CDC42BPA,ANK2,APAF1,FAM131A,LDLRAD4,CAPN3,HIP1R,TAOK2,RAB33A,CPS1,CLOCK,VCAN,CTH,RUSC2,GSDME,RCAN1,CGREF1,FYN,USP19,GNG4,CACFD1,BTN2A1,ELOVL5,TJAP1,IL6ST,SMAD1,MAP4,OGG1,P2RX7,P2RY1,RETREG1,SMOX,SLC25A23,MBOAT7,RPS6KA2,TSPYL2,DNMBP,CDK20,SMUG1,VIPR2,NT5M" Drug 4686_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "NDRG2,NME5,AMPD3,CDC42BPA,APC,CASK,CDK13,PDE8B,CFAP410,ARHGEF1,CREM,CSF1,PDE4DIP,CTH,RASSF2,FBXL5,PARD6A,SGSM2,PLXNC1,RASGRP2,FGF12,GLYR1,TM6SF1,MYT1,NF1,VPS13C,RAD51D,ROBO1,KCNIP1,FRMPD1,SLC22A4,LIMCH1,FNBP1,SP2,ZC3H13,SPART,TROVE2,NEK4,PCDHA6,AP4E1,ZKSCAN5,UBE3A,WIPF1,LAT2,SLC30A3,NT5M" Drug 4260_DN Picrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "MTUS1,C1QTNF1,APBB2,SHROOM2,HOMER3,WHRN,CPS1,PDE4DIP,DYNC1I1,DPH1,EDN1,ING4,COQ7,STX2,DENND4A,SPEG,ETV1,FGFR1,RUNDC3A,GLI2,KCNMB4,GPER1,BACH2,FAM69A,TM6SF1,MIA2,TAGLN3,NDP,PIK3R1,RETREG1,PRPH,PTPRN2,TMEM231,RAD51D,FAM184A,TRAPPC13,CSRNP3,FBXO11,LIMCH1,ARHGEF9,ZNF34,SSBP2,UGT8,WIPF1,EMSY,KCNAB1" Drug 2820_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-06 4.39E-02 5.35E-05 6.02E-04 46 195 "RALGAPA1,AP2A2,NME5,ALCAM,APBB2,GAS7,ARHGDIG,CFAP410,ARHGEF2,LHX2,FAM189A2,SH2B1,CSF1R,FAM169A,SPOCK2,DTNA,ZNF589,BAIAP2,FHL1,SEMA4D,CNTRL,HNMT,INPP5B,KCNH2,LMO2,MX1,LYRM9,ZNF862,PDE4A,SLC25A23,PRPH,RAD51D,ZDHHC14,ABLIM3,PEX26,SLC22A4,ZHX3,TSPYL2,CAMTA2,EXOC7,SYNE1,TK2,PARD3,DNALI1,GDPD5,EPM2A" Drug 4527_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-06 5.05E-02 6.01E-05 6.77E-04 44 184 "MARCH3,RGS9,ST3GAL5,BAIAP3,CA12,CAPN3,HIP1R,CRLF1,CHN2,ABCG1,VCAN,PDE4DIP,PLPPR4,FAM13A,IRAK4,TAOK3,FGFR1,PDLIM5,FYN,GAD1,PCDH17,STON1,SOX21,GUCY1B1,FAM69A,MAPT,MITF,SERPINI1,RETREG1,GRAMD1C,PRPH,RGS4,SH3GL3,ASAP3,ST8SIA1,KIF13A,ARHGAP26,SAMSN1,ELOVL4,CEP68,RGL1,SYT1,COBL,PLSCR4" Drug 1400_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 1.16E-06 5.09E-02 6.01E-05 6.77E-04 45 190 "ARNTL,MARK4,ST3GAL5,SCAPER,WASF1,HIP1R,CBFA2T2,LRBA,PPP1R16B,ZFYVE16,ZNF337,C2CD2L,GSDME,ANKRD46,FAM13A,MRNIP,EPB41L2,EXTL2,FGFR1,PDLIM5,ATP2C1,RUNDC3A,IFI16,MAP4,MEF2C,PCDH9,SERPINI1,CCSER2,RETREG1,GPSM2,PLCD1,MINDY2,PPM1B,PRKACB,PTX3,C1orf54,SATB1,ATXN2,FAM102A,CCDC88A,ZSWIM8,RGL1,STXBP1,CBX5,TRIM9" Drug 3379_DN Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-06 5.09E-02 6.01E-05 6.77E-04 45 190 "CDC42BPA,MPDZ,CFLAR,FOXN3,SOCS6,B4GALT6,LHX2,RAB28,QKI,ARMC8,MFAP3L,LYPD1,DTNA,STX2,FGFR3,BAIAP2,SYNCRIP,PDLIM5,MALT1,TXNL4A,SLC2A6,MUM1,JAK2,KITLG,MMP16,MPP2,NEK1,CEP97,GTDC1,ZNF821,BTBD7,ZHX3,SPART,CLASP2,TROVE2,THSD1,TACC1,TNS2,TMEM121,BEX4,RPRM,ZBTB14,ZIC1,REEP1,ST7" Drug 6884_DN AG-012559 [369370-06-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ASPHD1,SEMA7A,APBB2,CFAP410,SOCS6,HOMER3,SH2B1,CSF1R,PDE4DIP,PHF14,RIPOR2,ZFYVE16,RCAN1,DTNB,FEM1B,ING4,FGF1,TRAF3IP2,TMEM8B,HNMT,SHISAL1,INPP5B,KIF2A,MKLN1,CCSER2,C19orf57,PRKAR1B,RGS12,TRAPPC13,ZNF821,FBXO11,FAM214B,TMCC1,KDM4B,ZHX3,ASTN2,SATB2,TRIM2,ZNF34,TK2,LMF1,XRCC4,ZNF32,REEP1,SLC30A4,DPF3" Drug 7367_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "AP2A2,BIN1,CDK13,SYNJ2,SH2B1,CSNK1E,SLITRK5,DZIP3,EDNRA,ENO2,STX2,VPS26C,ST3GAL6,IQCG,TRMO,CINP,COPS8,AGBL5,AGFG1,FAM69A,MITF,NF1,SLC11A2,SETD4,PDE1C,PLCD1,RGS3,NUDT11,SUGCT,SBF1,SH3GL3,AMBRA1,NUBPL,FAM214B,KBTBD4,SLC22A4,ZKSCAN3,DOP1A,ANKRD12,TCF4,LMF1,ZNF189,MAP3K12,NT5M,ST7,PHTF2" Drug 7044_DN GSK-3 Inhibitor IX; Down 200; 0.5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ASPHD1,AP2A2,BIN1,CDC42BPA,GAS7,ATP6V0A1,SCAPER,CACNA1I,RUNX1T1,QKI,CNTFR,CSF1,DZIP3,CTH,DTNA,EGR3,PDLIM5,OGA,ERAP1,ALDH1L1,GLYR1,RAB30,KCNF1,MGAT3,ZNF862,NF1,PDE1C,RETREG1,RGS3,TCP11L1,RPS6KA2,EMID1,ZNF821,ASAP3,BTBD7,HECW1,VPS13A,SZT2,CHST8,TK2,PARD3,VGF,REEP1,UPF3A,SEMA3B,PLSCR4" Drug 4443_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "SEMA7A,N4BP2L1,CACNA1I,LDLRAD4,CAMK2B,RUNX1T1,ABCG2,MYRIP,CRY2,ARHGEF10,GREB1,ARHGEF4,GIT2,CHRDL1,EDN1,CELSR3,ELN,FGFR1,FYB1,FYN,ALDH1L1,PCDH17,RUNDC3A,GLI2,GLYR1,SYNPO,ITGA7,KCNH2,LIFR,LMO2,MAP2,AFDN,OXTR,PDE4A,PPP5C,MAPK7,ACSS3,ZMAT4,RGS4,HSPA4L,PDZD2,OBSL1,TPM1,LAT2,NT5M,KCNAB1" Drug 2073_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "CASK,BCL7A,SYNJ1,SYNJ2,MYRF,SPAG9,CNOT8,CLCN3,ABI3BP,NRG2,CTH,DCAF4,GIT2,FCF1,COQ7,VPS26C,HPCAL4,POLL,CACFD1,SOX21,IFI16,SHISAL1,KIFC3,LIG4,MAP4,MMP16,CNOT4,PPP5C,PRKAB2,APTX,PTPN13,RGS4,NUDT11,ZFP30,PPP4R3A,LHPP,TROVE2,LARP4,IQCE,KIAA0930,KAT6B,CABIN1,WIPF1,LAT2,SH3GLB2,MAP3K12" Drug 3175_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "SYN3,ALK,PRX,ARHGDIG,CACNB4,HAP1,EPS15L1,RAB33A,CLTB,AATK,JAKMIP2,FAM13A,C3orf18,CORO2B,OLFM1,FUT9,DISC1,PCDH17,STMN2,MAP2,ADAM22,NPY,PCBP3,TREM2,PALM,PDE1B,GPR85,PLXNB1,MAPK7,CCDC40,TRIM68,ASAP3,SLC6A8,SLC9A5,FAIM2,TSNAXIP1,UNC5B,PEG10,JMJD6,ADGRL3,CHST5,WIPF1,ZNF45,NT5M,DNALI1,ITM2C" Drug 1517_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ADORA2A,ADRA1D,KIAA1324,ADGRF5,SYT13,APOC1,MARK4,SYNJ1,CACNA1I,CFAP410,CAMK2B,RHBDL1,CACNA2D2,SOCS6,TAOK2,CSF1,CTH,ZNF804A,CDON,HSD17B14,F5,HPCAL4,PRELID3A,TMEM8B,DISC1,GATM,MSL3,GRB10,GSN,HNMT,TJAP1,INPP1,MAP2,MX1,SLC25A23,PPP5C,ELOVL2,ZSCAN2,SYBU,FAM214B,SLC11A1,ZNF423,SZT2,CDK20,XRCC4,PARP11" Drug 3349_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "NDRG2,NME5,CDC42BPA,APOC1,RGS20,ARHGEF7,CFAP410,CALB2,CHN2,LHX2,STOML1,FAM149A,NECTIN3,CNTNAP2,RIMS2,EXOG,DTNA,MBNL2,FAM198B,FHL1,GAD1,ALDH1L1,PCDH17,GLYR1,GNAO1,ADAMTS13,GSN,NXPH3,DHX35,TJAP1,LIFR,MGAT3,CNOT4,NTRK2,ZMAT4,TRIM68,RASA3,ELMO2,SNCA,CLSTN2,SLC19A3,THRA,CABIN1,TRIO,TRPM2,ITM2C" Drug 7495_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "AMH,BIN1,APAF1,APC,ARRB1,STX16,ARHGEF2,PLEKHB1,CHRNA4,TAOK2,DAPK3,BRINP1,RUSC2,RCAN1,CELSR3,EGFR,MBNL2,TENM1,STX2,ETV1,FGFR1,ANKFY1,GALC,SEPT9,INPP5K,DHX35,ICA1,MAPT,NFYA,PFKFB2,MBOAT7,ZSCAN2,SUGCT,SH3BP2,FRMPD1,ASAP3,PPP4R3A,MYH15,SP4,SPTB,CEP68,TRIM2,TRIO,SSBP2,SEMA3B,EPM2A" Drug 3321_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "AMPD3,GAS7,MARK4,SULT4A1,CNR1,PICK1,CNTN1,FAM149A,NCOR2,DCAF4,SPOCK2,DUSP9,HIPK3,PLXNC1,FGFR1,SEPT9,VSIG4,KHK,KIT,ADAM22,P2RY13,NPR2,GRAMD1C,SAMD9,C1orf54,RGS12,KCTD17,SLC11A1,SNCA,KIF13A,ZSWIM8,ST5,ARC,SYN2,SYT5,KIAA1107,DMXL2,PCDHGA10,OBSL1,CRTC1,TNS1,AMACR,VIPR2,SPHK2,DNALI1,SLC17A7" Drug 4645_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ADCY6,BIN1,CDK10,CDK13,B4GALT6,HOMER3,AKAP7,PDE4DIP,USP6NL,TBC1D5,GIT2,DBT,KIAA0753,PARD6A,FEM1B,FAM13A,MBNL2,ANKMY1,RRAGB,FGFR1,IQCG,ANKFY1,TRMO,DENND2A,ERAP1,ZNF276,DHX35,SHISAL1,NDP,NFYA,CNOT4,PLCD1,SAMD9,PTK2,PTPRN2,GTDC1,CLIP1,ASAP3,FAM214B,TMCC1,SS18,TCF4,GPR161,WIPF1,KLC2,EVI5" Drug 6678_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ADD2,ADRA1D,NME5,APAF1,APC,DNAH17,ADAM23,CHN2,TAOK2,PICK1,SH2B1,AATK,VCAN,ARHGEF4,SPOCK3,PLXNC1,TENM1,MTSS1L,FYB1,ZNF44,GNAL,GPR37,GRM8,HLF,LSS,MAPT,TM6SF1,MMP16,NF1,NOVA2,SLC11A2,SAMD9,KCTD17,ZNF821,MRAS,CNKSR2,NLGN1,SPTAN1,DDN,SLC44A1,THRA,TK2,VIPR2,WIPF1,XRCC4,NAV3" Drug 7409_UP Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ABHD6,NDRG2,C1QTNF3,EPB41L5,DNAH17,SCAPER,KYAT1,SLIT2,LY86,ENTPD4,SH2B1,DZIP3,HDAC4,GIT2,C2CD2L,EXOG,DMPK,PHF20L1,MBNL2,VPS13B,ERCC2,EZH1,F8,FGFR1,SRCAP,GRB10,GRIK5,RNFT2,ATXN2L,INPP1,MATK,MBD1,MIA2,PLCD1,MBOAT7,PTN,RIPOR1,RGS3,EPN2,COA1,PLCB1,DMXL2,CHST8,CHST5,VIPR2,ZBTB14" Drug 6667_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ACHE,PPFIA4,PPP4R4,ARHGDIG,ATP6V0A1,ADGRB2,HOMER3,CNTFR,AKAP6,CRMP1,PDE4DIP,PHF14,SPOCK2,MFAP3L,DTNA,DTNB,EDN3,PLEKHA1,EPHB1,NCALD,ETV1,REEP2,FGF1,FGF12,GPER1,CACFD1,ICA1,LIG4,KITLG,P2RY13,PCDH9,PDE4B,GPR85,LRRN3,PRPH,ZSCAN2,ENOX1,ZMAT4,SNCA,ZHX3,NFASC,COBL,CHST5,TRO,ZNF74,SPHK2" Drug 4597_UP Naringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "TRMT9B,ADAM23,MYRF,LDLRAD4,USP2,ARHGEF2,TAOK2,EPS15L1,LY86,CREM,CRY2,PDE4DIP,ARHGEF4,RIMS2,BRINP1,EDNRB,ETV1,F5,SEMA4D,EFCAB2,ZNF44,ADAM28,RUNDC3A,TPPP,GUCY1B1,ITGA7,KCNB1,KCNF1,KIFC3,LIG4,NNAT,PALM,PDE4D,ZSCAN32,RASGRF1,ZNF821,SH3BGR,WDR37,SLC2A5,SOX15,HECW1,IQSEC2,TK2,TLR4,ZNF74,GAN" Drug 5769_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ASPHD1,NME5,ANK2,CDC14B,PRX,KIF1A,ADGRB2,BMP7,CA12,CLDN10,SCARB1,MAGI1,HOMER3,WHRN,SPOCK2,HS3ST2,CDON,DTNA,EDN1,MBNL2,TNK2,EPB41,COQ7,ZNF549,ARMCX1,OLFM1,FAM49B,PADI2,SHISAL1,MAPT,AFDN,MMP16,PDE4D,GPR85,VPS13C,CCDC40,CARF,PPM1E,DZIP1,SLC12A4,SP4,PLCB1,DOCK9,CDK20,TRO,EVI5" Drug 2295_UP Riluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "NDRG2,ADD2,ADORA1,SYT13,APBA2,APC,GAS7,ATP1A3,CALB2,CAMK2B,SEPT7,ARHGAP33,CHN2,WHRN,CABP1,COL9A3,CRMP1,ARHGEF10,DCAF4,SPOCK2,EDNRA,ING4,ERCC2,F5,FGFR1,NEU3,GPR37,HNMT,KCNB1,AFDN,ADAM22,OPRL1,CLDN11,RELN,KCTD17,SH3GL3,PEG10,SPTB,ARC,TBCEL,PCDHGA10,PCDHA5,ICAM5,FAM155A,WIPF1,ITM2C" Drug 4122_DN Boldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ADORA2A,AP2A2,AMH,AMPD3,BIN1,SEMA7A,APLP1,MARK4,SCAPER,CAMK2B,PLEKHB1,TAOK2,TPP1,STOML1,CLTB,CPS1,SH2B1,CYBB,RUSC2,CELSR3,VPS26C,FGFR1,KHDRBS3,GLYR1,RAB30,GPER1,SPACA9,GRIK5,DHX35,TJAP1,IL6ST,KIF5A,IPO5,LMO2,SERPINI1,CPEB3,FUZ,SPTAN1,CLSTN2,THSD1,PLCB1,PDLIM2,R3HDM1,LAT2,XRCC4,HPS4" Drug 5979_UP PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "MTUS1,BEGAIN,DOC2A,APAF1,ARHGDIG,SLC4A4,NRP2,MYRF,BAIAP3,IL33,CACNA2D1,MAGI1,HOMER3,PICK1,NCOR2,CSF1,VCAN,EDNRA,ING4,ETV1,SCML2,GNAL,STON1,HLF,ICA1,TM6SF1,PALM,CDK18,BCAS3,RASGRF1,KCTD17,KIRREL1,FBXW7,EMID1,ASAP3,AMBRA1,ZHX3,KDM4C,TROVE2,CRTC1,TK2,RUNDC3B,TRO,WIPF1,MAP3K12,PCBP4" Drug 3760_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ASIC1,AMPD3,APOC1,ARRB2,ALDH7A1,BMP7,SYNJ1,SYNJ2,ARHGEF7,CFAP410,SCARB1,LY86,WHRN,SLC4A8,MFAP3L,EXOG,CNNM1,ING4,ETV1,FGFR1,PRELID3A,TMEM8B,DISC1,USP19,GLI2,POLL,RASSF8,INPP5B,JAK2,LIFR,NDP,PPARA,PRPH,CNNM2,SUSD4,SNCA,FNBP1,UNC5B,TROVE2,THSD1,PHLDB1,COBL,ZEB1,TNS1,NT5M,TIGD6" Drug 1713_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "NDRG2,APBA2,APBB2,CDK10,ENTPD6,RCBTB2,PICK1,CSF1R,OSBPL3,DOCK4,GIT2,FEM1B,VPS26C,EZH1,GFER,PRRC2B,LILRA2,NF1,NFYA,NTRK3,NUCB2,CLDN11,CCSER2,ZFYVE21,NLE1,SMOX,MBOAT7,MINDY2,CCDC40,TCP11L1,SAFB,SATB1,CCDC88A,ELMO2,INTS9,KDM4C,ARHGEF9,NACC2,KAT6B,TNS1,PIK3R5,PLPPR2,XRCC4,HPS4,NLRP3,RNF170" Drug 2493_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ABR,NDRG2,KCNAB2,APC,ARRB1,NCOA1,BACH1,SYNJ1,MTMR2,SLC25A14,CD86,RAB33A,ARMC8,VCAN,DGKG,DBT,RCAN1,DTNA,HIPK3,COQ7,CD320,F5,KAT8,FHL1,POLL,ATXN2L,IL6R,KIF2A,MEF2C,N6AMT1,NF1,PTPRN2,RNASEL,PLPPR3,SEC14L1,MRAS,EPN2,SLC11A1,DOK5,SS18,CEP68,ADGRL3,TCF4,FLRT2,XRCC4,PHTF2" Drug 3971_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ADORA1,AGT,GAS7,ARSE,PDE8B,CACNA2D1,CD86,STOML1,WHRN,CSF1,RIPOR2,DGKG,ERCC2,REEP2,FLNC,SIGLEC8,GDF9,GRM8,IRAK3,IFI16,SHISAL1,KCNN1,MEF2C,ADAM22,MYO7A,FXYD7,NOVA2,NTRK2,NTRK3,ACSM5,C1orf54,BEND5,KHDRBS2,CRTAC1,SCN8A,CNKSR2,ST8SIA1,IZUMO4,HECW1,CDK19,TAL1,TCF4,CHST5,LAT2,ZNF154,FAM13C" Drug 5736_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "NDRG2,TRMT9B,EPB41L5,ARRB1,N4BP2L1,GYG2,CACNA1I,BAIAP3,PLEKHB1,RAB26,ARHGEF6,HAPLN1,MFAP3L,SPOCK3,ING4,EZH1,NRN1,DLC1,KAT8,FGFR1,NEU3,GPR162,TDRKH,GSTM5,IL6ST,INSM1,JAK2,MEF2C,MYH3,PDE4D,PPP5C,MAPK10,VPS13C,ZSCAN2,TMEM255A,ACSS3,KHDRBS2,CNKSR2,PREX2,SLC11A1,HECW1,IQSEC2,MCF2L,AMACR,SPHK2,SENP7" Drug 7333_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "OSBPL1A,NME5,CDC42BPA,CFLAR,CAMK2G,USP2,CLGN,SOCS6,ZFYVE16,GIT2,DMPK,OPTN,EGFR,IRAK4,ERCC2,EZH1,AGAP2,SRCAP,TXNL4A,TDRKH,LPAR4,HSF2,INPP5B,IPO5,LSS,MAP4,TM6SF1,NF1,CNOT4,NPTX1,PDE4B,PMP22,VPS13C,PTCH1,GTDC1,ROBO1,FBXW7,SBF1,ZNF821,SMARCC2,SNCA,VPS13A,GPR161,HIRA,ZNF142,SLC17A7" Drug 3970_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "ASIC1,GAS7,APOC1,CDK10,PDE8B,CBFA2T2,TAOK2,CLTB,CSF1,RIMS2,PPP6R2,DCAF4,RUSC2,EDNRA,FEM1B,EGFR,RASGRP2,F5,TRMO,DLL3,GAD1,GPER1,GRIK5,CACFD1,INPP5B,KCNJ5,KCNN2,KCNQ3,NF1,CLDN11,PLCD1,PTPRD,RPS6KA2,SEMA6D,PEG10,ZC3H13,TROVE2,EXOC7,CRTC1,FAM155A,VIPR2,ZFP37,ITM2C,MPPE1,PLSCR4,ADAMTSL3" Drug 833_UP 5255229; Up 200; 13uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.17E-06 5.11E-02 6.01E-05 6.77E-04 46 196 "NDRG2,ARHGDIG,SLC2A11,BACH1,SCAPER,MTMR3,GYG2,CFAP410,SRSF11,RCHY1,CREM,ENTPD4,ABCG1,CTH,ARHGEF4,RIMS2,PPP6R2,DBT,BAIAP2,SYT17,CNTRL,GRM8,MAP4K5,LYRM9,CNOT4,PALM,PRKAR1B,MAPK7,PRPH,ZSCAN2,SUSD4,RNASEL,ROBO1,TCP11L1,SCN2B,FNDC3A,NLGN1,BTBD7,DDN,CEP68,PHLDB1,SMG6,ZNF34,TRIO,VIPR2,EVI5" Drug CID000000238 laevadosin Stitch 1.22E-06 5.34E-02 6.26E-05 7.05E-04 268 1800 "SYN3,CLK4,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,NME5,AK2,TAOK1,ALK,AMPD2,AMPD3,MAP4K3,MYH7B,APAF1,APC,CDK10,MADD,CASK,ARNTL,ARRB1,CDK13,STK33,MARK4,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,RIPK1,KIF1A,BCS1L,BMPR1B,NAE1,BTK,AP1M1,DDR1,CACNA2D1,CALM1,CAMK2A,CAMK2B,CAMK2G,CARS,CCNH,CCNT1,P2RX6,CD38,ENTPD2,DGKI,LRBA,CDC25B,DCLK1,UBE2L6,SRSF11,ASIC3,TAOK2,MYL6B,CLTC,ABCG2,CPS1,CREM,ABCG1,CS,CSF1R,CSNK1E,CSNK1G3,PLCXD3,ZFYVE16,EARS2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DCTN1,DMD,DMPK,NR1D2,FARSB,ABCC5,E2F5,EDN1,HIPK3,EGFR,EIF4G1,EIF5,IRAK4,TNK2,ENO2,EPB41,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,KATNAL1,ACSL4,TUBA1B,PTK2B,TUBB3,TAOK3,STRADA,PPP1R1B,FER,FGF1,POLR1B,FGFR1,FGFR3,PRKAG2,POLK,ATP5PD,UBE2E3,IP6K2,VTI1B,FOXO3,FLT1,NELFCD,DCTN2,AK8,TPK1,CAMKK2,ATP6V1H,ATP2C1,BRSK1,FYN,IP6K3,MTHFD2,ACSS1,GCK,GGT7,GGT5,MALT1,TTBK1,DBF4,GLUL,DCLK2,GNAL,GPD2,LPAR4,PLCD4,CIT,MAP4K5,IRAK3,HBA1,HMGCR,MYLK2,ITPKA,ITPKB,JAK2,KHK,KIT,LIG4,SMAD1,MARK1,MARK3,MATK,MBP,MEF2C,KITLG,AFDN,MYH3,MYO5A,MYO6,MYO9A,P2RY13,NEK1,NME4,NPY,NTRK2,NTRK3,KSR2,P2RX7,P2RY1,CDK18,PDE4B,PDE4D,PDPK1,PFKFB2,PFKFB3,PFKFB4,ABCB1,PIK3C2A,PIK3R1,PKM,PLCB2,PLCD1,PLIN1,POLG,POLR2F,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PRPSAP2,NDUFS7,PSMA6,SNRK,PTK2,ACSS3,RAD17,RET,REV3L,RORB,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,RPS20,HUNK,MAPK12,SARS,FOXRED1,SGK1,MYO18A,SEPHS1,MAST1,NMNAT2,CDK19,NEK4,TTBK2,SUPT5H,PLCB1,SYN2,SYT1,TAF6,MLST8,TAF9,SMG6,TCEA1,CLASP1,SLC19A3,TEK,TK2,TLR4,CDK20,NPL,TRPM2,TSC1,TSC2,SGK3,TUBB1,UBC,UBE2H,UBTF,P2RY12,RICTOR,SPHK2,POLR3H,MAP3K12,PRTFDC1,TUBA1A,WNK3,WNK2,NELFE,ACTR3B" Drug 1398_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; HL60; HG-U133A Broad Institute CMAP Up 1.28E-06 5.60E-02 6.53E-05 7.35E-04 41 167 "BIN1,APAF1,GAS7,ARRB2,DNAH17,CFLAR,SLC25A14,CD86,CD38,ARHGAP33,FOXN3,CHN2,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,GIT2,FAM13A,EPB41L2,OGA,TRAF3IP2,MALT1,GLUL,PACSIN2,HNMT,NCF2,PDE4B,PDE4D,GPSM2,PLCD1,SMOX,QDPR,SGK1,SLA,ATF7IP,LMBRD1,ZSWIM8,SPTAN1,PLCB1,FLRT2" Drug 7005_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.33E-06 5.84E-02 6.53E-05 7.35E-04 43 179 "ABHD6,NME5,BMP7,ST3GAL5,SCAPER,GYG2,CLGN,AKAP12,PDE4DIP,ARMCX2,TSPAN5,ENO2,CDKL3,BAIAP2,FYN,CYP46A1,RAB40B,STON1,KCNH2,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,PMP22,PKIA,PRPH,SH3GL3,PPM1E,ASAP3,WDR47,CCDC88A,THSD1,ELOVL4,RGL1,STXBP1,AGTPBP1,TRIM2,HEY1,RUNDC3B,SSBP2,ZNF45,MARCH8" Drug 6951_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.33E-06 5.84E-02 6.53E-05 7.35E-04 43 179 "MARK4,BMP7,ST3GAL5,BAIAP3,SPAG9,USP2,AKAP12,CRYM,PDE4DIP,ARMCX2,JAKMIP2,OPTN,RASGRP2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,TDRKH,STON1,MITF,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,RETREG1,PRPH,SEC14L1,SH3BGR,SH3GL3,WDR47,SLC6A8,SPTAN1,RGL1,STXBP1,SMG6,HEY1,BEX4,RUNDC3B,SSBP2,SLC30A3,SLC17A7" Drug 5906_UP valinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.35E-06 5.90E-02 6.53E-05 7.35E-04 44 185 "ADORA2A,SEMA6A,BEGAIN,ANK2,CAMK2B,ARHGEF2,CDH2,CLGN,QKI,NRG2,FAM169A,RUSC2,DTNA,MBNL2,DLC1,AMOTL2,FHL1,TPK1,GAD1,RUNDC3A,GRB10,ADAMTS13,HLF,JAK2,AFDN,NF1,NOVA2,RETREG1,MINDY2,PPP5C,RPS6KA2,SH3BP2,PPM1E,CPEB3,SNCA,UNC5B,CDK19,WSCD1,HEY1,RUNDC3B,TRPM2,VLDLR,LAT2,SLC30A3" Drug 2949_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.35E-06 5.90E-02 6.53E-05 7.35E-04 44 185 "ABHD6,APBB2,APC,ST3GAL5,LDLRAD4,HIP1R,LHX2,CLCN3,RAB26,CSNK1E,PDE4DIP,GPRASP1,ZNF337,KLHL3,GSDME,OPTN,TNK2,MRNIP,ETV1,FHL1,GATM,RAB40B,STON1,PADI2,ITGA7,MEF2C,AFDN,ADAM22,PCDH9,SERPINI1,GPSM2,RIPOR1,PPM1E,EPN2,SLC9A5,SPTB,ELOVL4,RGL1,STXBP1,PDLIM2,TNS2,MAP3K12,GDPD5,FZD3" Drug 6916_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.35E-06 5.90E-02 6.53E-05 7.35E-04 44 185 "ABHD6,ARNTL,MARK4,SYNJ1,ST3GAL5,SPAG9,CLGN,PREPL,AKAP12,PDE4DIP,CTH,ARMCX2,CDKL3,BAIAP2,NBEA,FYN,CYP46A1,RAB40B,STON1,NEK1,PCDH9,SERPINI1,PRPH,PTCH1,PTPN13,SH3BGR,SH3GL3,KIF16B,SYBU,WDR47,SPATA7,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,DOCK9,HEY1,ACTR6,BEX4,RUNDC3B,SSBP2,EVI5,SLC17A7" Drug 2137_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 45 191 "MTUS1,BIN1,APBB2,ST3GAL5,SGCE,HIP1R,LHX2,RAB26,ABCG1,PDE4DIP,DOCK4,MAMLD1,MBNL2,ENO2,ETV1,BAIAP2,NBEA,ADAM28,PCDH17,STON1,PADI2,TJAP1,FAM69A,ITGA7,MEF2C,ZNF862,PCDH9,PCSK5,SERPINI1,PLCD1,PTPN13,RIPOR1,TMEM255A,ROGDI,CCDC92,ANKRD6,SPTAN1,CEP68,RGL1,STXBP1,OBSL1,ICAM5,CLIP2,KLC2,MAP3K12" Drug 3058_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 45 191 "NDRG2,SEMA6A,BIN1,EPB41L5,KALRN,CDO1,CLGN,CHN2,LHX2,RAB26,DZIP3,DOCK4,AASS,EPB41,EPHB1,APC2,ETV1,TLR7,TBC1D16,NBEA,SIGLEC8,GATM,ADAM28,GLI2,STON1,HNMT,MAPT,NF1,PCDH9,PCSK5,SERPINI1,PLCL1,PMP22,MARCH1,TMEM255A,RASGRF1,SMARCD3,PEG10,ELOVL4,RGL1,KLC2,KCNK12,MAP3K12,SLC17A7,FZD3" Drug 2810_UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ALCAM,ALK,AMPD3,SEMA7A,APAF1,DNAH17,ATP2B2,CACNA1I,BAIAP3,CD86,ARHGEF1,CBFA2T2,RAB33A,CNTNAP2,HS3ST2,EDIL3,C3orf18,VPS13B,PIPOX,ZNF589,AFF2,FUT9,GCNT2,MSL3,CNTRL,GSN,KCNN1,KCNQ3,TREM2,PAX6,PLCD1,PRKAR1B,CCDC40,C1orf54,RPS6KA2,STUM,CNKSR2,STX1A,DOCK9,CABIN1,TRIO,LAT2,SEMA3B,PLSCR4,KAT6A,SENP7" Drug 3794_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASPHD1,NME5,BIN1,SEMA7A,PKP4,KCNAB2,EPB41L5,BMP7,CBS,ARHGAP33,TPP1,AKAP7,CREM,RIMS2,MFAP3L,DUSP9,PRELID3A,MSL3,KCNMB4,ELOVL5,SCIN,ITPKA,KIFC3,KIT,LMO2,MAP2,CLDN11,PFKFB2,KCTD15,PLXNB1,RASA3,ASAP3,ST6GAL1,FAM214B,ARHGEF40,SLC9A5,RBM34,TSNAXIP1,ZHX3,LHPP,THSD1,PLCB1,DOCK9,VGF,WIPF1,SMIM8" Drug 4116_UP Cefotetan [69712-56-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "PRX,MARK4,N4BP2L1,NRP2,CACNA1G,CALB1,USP2,MTMR7,ARHGEF2,LHX2,WHRN,MYRIP,RIMS2,TMCC2,CDON,EDN3,EDNRB,FAM13A,EGFR,PLXNC1,TENM1,TNK2,LRRC17,RASGRP2,EPHB1,NRN1,FAM198B,OLFM1,PDLIM5,OGA,SRCAP,KCNN1,MAPT,CLDN11,PPARA,PTPRB,C1orf54,TRIM68,SLC2A5,SLC11A1,PEG10,TACR1,SYNE1,PIK3R5,TRIO,SLC30A3" Drug 3551_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADCY6,KIAA1324,ADGRF5,SPARCL1,APBA2,APLP1,SEMA4G,PTCH2,SLC2A11,ARHGAP33,RCBTB2,ASIC3,ARHGEF6,CNR1,PDE4DIP,CNTNAP2,SNPH,CDON,RCAN1,TENM1,ERCC2,VPS26C,F5,FYB1,FYN,TMEM8B,GPER1,ADAMTS13,MAN2A2,MEF2C,MN1,PCBP3,LRP12,PPARA,MINDY2,RGS12,RPS6KA2,SEMA6D,SH3BP2,FRMPD1,WSCD1,ZEB1,DOCK9,PCDHA3,R3HDM1,GDPD5" Drug 6335_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADORA2A,KCNAB2,PPP4R4,MARK4,SLC4A4,SYNJ2,BAIAP3,IL33,HIP1R,ARHGAP33,CREM,VCAN,RIMS2,ARHGAP24,TBC1D5,SEMA3D,FAM13A,TENM1,IGSF6,ETV1,ZNF589,SEMA4D,ADAM28,GFER,GLYR1,LPAR4,INPP5B,TM6SF1,MIA2,PPARA,GAL3ST4,KCNIP1,ZFP30,FRMPD1,CDK5RAP2,SMARCD3,IFT122,KDM4C,PHLDB1,ZEB1,OBSL1,NSD1,TK2,ICAM5,UBE3B,GAN" Drug 7037_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASPHD1,NDRG2,CDC42BPA,BCAS1,NUMB,CFLAR,ARHGEF7,SIPA1L1,PDE4DIP,DZIP3,DCAF8,ZNF337,PARD6A,MED12,CDON,DTNA,MAMLD1,F8,CRCP,GNG4,GRB10,RNFT2,MAPT,ADAM22,NEK1,NFYA,PPP2R2B,TMEM104,NKAIN1,ZCWPW1,GTDC1,SH3BP2,FUZ,WDR47,BTBD7,CDK19,SPART,CEP68,MCF2L,TMEM121,CHST8,BEX4,UBTF,ZNF142,TFIP11,GAN" Drug 5835_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "APBB2,APOC1,SEMA4G,CDK13,CFLAR,B4GALT6,CNOT8,ARMC8,AKAP12,NCOR1,GIT2,DBT,ARMCX2,SGSM2,MRNIP,STX2,ANKMY1,SYT17,INPP5K,GLI2,DIDO1,GRIK5,IL6R,JAK2,LAMA2,MAPT,MKLN1,TAGLN3,NF1,PID1,RBBP6,MORC4,TCP11L1,ZNF415,TMCC1,TROVE2,SAMSN1,TACC1,IQCE,TRIM2,PHF24,HIRA,WIPF1,EMSY,CIAPIN1,RNF146" Drug 2848_DN Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "APC,STX16,CFLAR,CA4,CLGN,HOMER3,COL4A5,CREM,SOCS5,PDE4DIP,RCAN1,DTNA,EDNRA,FCF1,CNNM1,FAM198B,FHL1,TPK1,ERAP1,SRCAP,CRCP,RAB30,IL6ST,MAP4,MMP16,ADAM22,LYRM9,NPR2,NPTX1,FAM184A,TCP11L1,SBF1,FAM214B,CDK19,ST5,PLCB1,ARC,ZNF34,SLC44A1,TK2,VGF,VIPR2,REEP1,EMSY,PCBP4,PHTF2" Drug 5072_DN Pizotifen malate [5189-11-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "CDC42BPA,MYRF,FOXN3,TAOK2,LHX2,RAB28,SLC4A8,HAPLN1,VCAN,DZIP3,GIT2,KLHL3,PARD6A,EDIL3,ETV1,SEMA4D,PRRC2B,CNTRL,GUCY1B1,RASSF8,BACH2,HNMT,SHISAL1,INPP5B,ITPKB,MAPT,NDP,NF1,SETD4,PLCD1,MAPK7,ELOVL2,ZSCAN2,SH3TC2,CCDC25,FAM192A,ATXN7,DZIP1,SLC14A1,SPTAN1,ASTN2,CRTC1,THRA,TK2,VIPR2,NDRG4" Drug 3188_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AMPD3,KCNAB2,APOC1,ARHGDIG,ATP2B2,N4BP2L1,AZGP1,RGS9,CALB1,HAP1,ARHGEF2,SLIT2,HOMER3,CABP1,JAKMIP2,TENM1,FGF12,FHL1,PDLIM5,TDRKH,HLF,JAK2,KCNN1,MAP4,MMP17,GIT1,CDK18,PFKFB2,PLCD1,NECAB2,PPP5C,DCHS2,PBRM1,FBXO11,SLC6A8,SLC11A1,SLC14A1,OGDHL,SNAP25,KDM4B,SPTAN1,SYT5,EXOC7,SZT2,UGT8,GDPD5" Drug 3698_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADD2,FAM135A,PPFIA4,PTCH2,ATP1A3,N4BP2L1,ADAM23,KSR1,BMP7,GYG2,CACNA2D1,DCLK1,VAX2,AKAP5,CSF1,EXOG,DTNA,EDN1,FCF1,MTSS1L,ANKFY1,SIGLEC8,POLL,HSF2,C2orf72,KCNH2,KIFC3,LAMA2,SMAD1,TAGLN3,NF1,OPRL1,CDK18,MARCH1,RGS12,KCNIP1,AMBRA1,SLC2A5,FAIM2,ARC,PCDHA5,GPR161,TK2,TRO,EPM2A,NLRP3" Drug 4604_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ALK,SLC4A4,N4BP2L1,KSR1,CACNA1G,CACNA2D1,CAMK2B,RAB26,CNTFR,CABP1,NRG2,VCAN,PDE4DIP,MFAP3L,C2CD2L,PLPPR4,EDNRA,HIPK3,EIF5,COQ7,ETV1,SIGLEC8,SYT17,GNAL,GNG4,PTPRT,LSAMP,MSR1,LYRM9,NTRK3,P2RX7,RETREG1,PRPH,ENOX1,NEK11,CSRNP3,NLGN1,ANKRD6,SNAP25,ARHGAP26,ARC,TACR1,RPRM,VGF,VIPR2,GJC2" Drug 4504_UP Iopromide [73334-07-3]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AMPD3,BMPR1B,CBS,CD86,HOMER3,NCOR2,ARHGEF10,PDE4DIP,PHF14,MAML1,ARMCX2,MFAP3L,DMPK,EDNRB,APC2,EZH1,OLFM1,FLT1,DCTN2,ZNF44,CACFD1,SOX21,PADI2,IRF8,JAK2,MMP17,GIT1,MT1M,MYO7A,NPR2,PDE4D,ENPP2,MAPK7,PTPRN2,ZSCAN2,RGS12,RASA3,FBXO11,SMARCA4,TSNAXIP1,FNBP1,ZBTB43,SMG6,ZFPM2,EPM2A,PHTF2" Drug 4993_UP Estrone [53-16-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADRA1D,BEGAIN,APAF1,N4BP2L1,AZGP1,SCAPER,CFAP410,CALB2,CCK,FOXN3,SULT4A1,CNTFR,FAM149A,NRG2,DNAH9,EGR3,ING4,HSD17B14,ZNF549,NRN1,FUT9,PCDH17,RUNDC3A,GRIK5,ATXN2L,ICA1,MID1,AFF1,MYCN,OPRL1,PLEC,ELOVL2,ZNF493,PNMA8A,ZNF334,NFASC,PLCB1,TBCEL,WSCD1,SZT2,TK2,TNS1,REEP1,NT5M,SEMA3B,KCNAB1" Drug 3388_UP Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG2,ADORA1,ADRA1D,MARK4,N4BP2L1,CACNA1I,CACNA2D1,CAMK2B,CAST,CACNA2D2,SLIT2,TPP1,WHRN,SLITRK5,INTS1,DGKG,DAPK3,EGR3,ERCC2,GABRG2,GATM,GPER1,GRB10,GRIK5,GRM2,NXPH3,TJAP1,ITGAM,JAK2,MAN2A2,MAP4,MGAT3,NF1,NPR2,TREM2,MAPK7,ZDHHC14,RET,RGS12,SYBU,ATP10B,ARC,CRTC1,TIAM1,SEMA3B,EPM2A" Drug 4530_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "RALGAPA1,ASPHD1,C1QTNF1,APC,APOC1,KIF1A,CBFA2T2,ARHGEF2,AKAP5,SLC4A8,ABCG1,MFAP3L,EDIL3,EDNRA,MRNIP,C3orf18,FGFR1,PRELID3A,USP19,MSL3,SHISAL1,IL6ST,ITPKA,MN1,MX1,NDP,PALM,PCDH9,LRP12,SAMD9,CNTLN,PID1,RPS6KA2,FUZ,PPP4R3A,FAM214B,CCDC88A,SNCA,TROVE2,ASTN2,TRIO,AMACR,RPRM,NDRG4,NAV3,PCBP4" Drug 6964_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NME5,LTBP4,BIN1,FAM131A,APOC1,SEMA4G,MARCH3,MARK4,CACNA1I,QKI,COL4A5,MYRIP,GPRASP1,ARHGAP32,JAKMIP2,OPTN,EZH1,ACSL4,DLC1,FECH,CACFD1,IL6R,ITGA7,MAN2A2,MAP4,MBD1,ZNF862,PTPRE,RGS12,ZFHX4,FBXW7,PEX26,PKNOX2,MYH15,TSNAXIP1,IQSEC2,ELOVL4,STX1A,ADGRL3,WSCD1,KIAA0930,TNS2,DNAH7,TK2,TPM1,KCNAB1" Drug 5744_DN Calycanthine [595-05-1]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASIC1,C1QTNF3,APBB2,APC,PPP4R4,CDK13,STX16,ALDH7A1,SCAPER,LARGE1,CHN2,TPP1,SULT4A1,AKAP7,VCAN,ARHGEF4,MFAP3L,TOM1,TENM1,STX2,ERCC2,PDLIM5,OGA,TRAF3IP2,SRCAP,GNG4,KCNH2,MAPT,MMP16,MX1,NLE1,CCDC40,SLC2A5,KDM4D,SLC14A1,ZNF415,SAMSN1,KIAA1107,CHST8,GPR161,CABIN1,XRCC4,ZNF32,ZNF74,TFIP11,EVI5" Drug 4003_DN Tolazamide [1156-19-0]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "TRMT9B,APC,GAS7,KIF1A,MYRF,ARHGEF1,LHX2,CREM,SH2B1,ARHGEF10,AASS,MTSS1L,STX2,EZH1,AFF2,CINP,GAD1,GFER,MSL3,POLL,TDRKH,GPER1,SHISAL1,MN1,CNOT4,NOVA1,PPP5C,WDR25,ENOX1,RPS6KA2,FRMPD1,FBXO11,SNCA,TSNAXIP1,ARHGEF9,ADGRL3,KIAA1107,KIAA0930,TRIM2,THRA,TK2,AMACR,XRCC4,REEP1,EMSY,NT5M" Drug 6337_UP Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADRB2,NME5,LTBP4,APBB2,SEMA4G,PPP4R4,STX16,CFLAR,CFAP410,CD86,SCARB1,NRXN3,CREM,ENTPD4,SH2B1,GPRASP1,SPOCK2,RCAN1,FAM13A,EGFR,ELN,TRAF3IP2,IQGAP2,ERAP1,GLYR1,MSL3,PRUNE2,SPACA9,SOX21,ATXN2L,SHISAL1,TJAP1,KCNB1,MGAT3,MIA2,PDE4D,POLG,PPP5C,GAL3ST4,RNASEL,EXOC7,FAM189A1,CRTC1,PCDHA6,XRCC4,DPF3" Drug 6012_DN Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AMH,APBA2,APLP1,EIF4G3,SLC2A11,ALDH7A1,ADAM23,LDLRAD4,PLEKHB1,HOMER3,BAG4,AKAP12,CNTNAP2,CDON,STX2,DENND4A,ANKMY1,FAM49B,MSL3,POLL,TDRKH,MAP4,TM6SF1,MMP16,MPP2,LRP12,POLG,MINDY2,PTN,CEP97,MRAS,ASAP3,CXXC4,SNCA,ZHX3,TTBK2,PLCB1,MCF2L,EXOC7,IQCE,CRTC1,PCDHA6,RIMBP2,VLDLR,LMF1,GDPD5" Drug 3737_UP Myosmine [532-12-7]; Up 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASPHD1,NDRG2,ADD2,LTBP4,AMPD3,APAF1,APOC1,PPP4R4,KIF1A,NRP2,CRLF1,SULT4A1,AKAP5,SLC4A8,PDE4DIP,RIMS2,MFAP3L,DTNA,FCF1,KAT8,GNAL,GPD2,GRIK5,SOX21,MAP4K5,TJAP1,KCNJ5,LSS,MMP16,ADAM22,NF1,NNAT,CLDN11,LRRN3,KCNIP1,SEMA6D,SCN8A,ZNF821,FNDC3A,KDM4C,SYT5,ZEB1,OSBP2,LAT2,KAT6A,RNF146" Drug 4744_DN Tropicamide [1508-75-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG2,ADRA1D,TRMT9B,AMT,APC,GAS7,ALDH7A1,CFLAR,MTMR3,CBFA2T2,SIPA1L1,CNTNAP2,RIMS2,EDNRA,EIF4G2,KAT8,FGFR1,GCNT2,GLYR1,STON1,GRM8,IL6ST,MID1,MMP16,NFYA,CNOT4,PDE4A,SERPINI1,RETREG1,NLE1,SAMD9,RGS12,FAM214B,DOP1A,ZNF423,ZC3H13,PLCB1,PCDHA5,CHST8,THRA,CDK20,HIRA,FAM155A,SPHK2,EMSY,EPM2A" Drug 2821_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AK2,ALCAM,APBA2,APOC1,ARRB1,DNAH17,ALDH7A1,BAIAP3,CBFA2T2,WHRN,RCHY1,EXOG,PHC2,STX2,KAT8,ZNF589,FGFR1,ANKFY1,OGA,GCNT2,TDRKH,GPER1,ADAMTS13,ICA1,KCNQ3,MX1,PLCD1,LRP12,POLG,CEP41,PRKAR1B,PRODH,PTCH1,TRIM68,RXRA,CNKSR2,SMARCC2,SPART,SZT2,PCDHGA10,TK2,RUNDC3B,LMF1,LAT2,MAP3K12,SEMA3B" Drug 7321_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADORA2A,NME5,AMH,APBB2,ARHGDIG,CACNA2D2,ARHGEF6,CNNM1,ING4,C3orf18,STX2,EZH1,FECH,FER,IQCG,ERAP1,NEU3,TXNL4A,POLL,FERMT2,TDRKH,STON1,CNTRL,CACFD1,ATXN2L,TJAP1,MAP4,KITLG,NF1,ELOVL2,RAD51D,RPS6KA2,SBF1,AMBRA1,SLC22A4,LIMCH1,SNCA,RBM34,PHLDB1,PLCB1,MTCL1,ADGRL3,AP4E1,ZKSCAN5,EVI5,ITM2C" Drug 2129_UP Retrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ALK,BIN1,PPFIA4,APAF1,FAM131A,AQP6,SEMA4G,KIF1A,NRP2,PICK1,ABCG1,SPOCK2,BRINP1,HS3ST2,CDKL3,REEP2,KAT8,EFCAB2,ALDH1L1,ADAM28,LILRA2,GRIK5,GSN,ICA1,KHK,MAP4,SCAMP5,MPP2,ZNF862,NTRK2,PLCD1,PRKAB2,BCAS3,ZCWPW1,KLHDC8A,KCNIP1,ZNF821,STUM,SNAP25,TSPYL2,TBCEL,CDK20,WBP2,UGT8,ZNF74,GDPD5" Drug 2222_DN Amidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "LTBP4,BIN1,KCNAB2,EPB41L5,MARK4,CFLAR,BMP7,MTMR2,ARHGEF2,LHX2,PICK1,SH2B1,CRY2,ARHGEF4,SEC14L5,CDON,RCAN1,ING4,ZNF589,ANKFY1,FAM49B,PRELID3A,INPP5K,GLYR1,RNFT2,SLC2A6,RASSF8,HNMT,ICA1,KCNN2,LMO2,LSS,MPP2,NPR2,PTN,ZSCAN32,RIPOR1,ZDHHC14,GSTCD,PEX26,ARFGAP1,EXOC7,HPS4,SEMA3B,URM1,UBE3B" Drug 5734_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "PKP4,APOC1,N4BP2L1,ADGRB2,CBS,PLEKHB1,STOML1,RAB26,IQCK,RIPOR2,DAPK3,MFAP3L,C2CD2L,SPOCK3,DMPK,ING4,MTSS1L,NCALD,IGSF6,NEU3,GPR75,GNAL,SOX21,ATXN2L,IL6ST,ITGA7,MGAT3,ADAM22,PDE4D,GPR85,PPP2R2B,PPP5C,NEK11,ATXN7,STUM,PPP4R3A,KDM4B,LHPP,SZT2,FAM189A1,TIAM1,RPRM,VAV1,ZFP37,SEMA3B,JPH3" Drug 2536_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASIC1,NDRG2,TRMT9B,AMT,CDC42BPA,KCNAB2,LDLRAD4,CAMK2G,AKAP7,IQCK,DAPK3,DBT,RUSC2,RCAN1,DTNA,MTSS1L,F8,ANKFY1,SEPT9,COPS8,MSL3,GRM8,NCKAP1L,ZNF862,NNAT,PDE4D,RETREG1,MINDY2,MAPK3,PTK2,ZSCAN32,FRMPD1,EPN2,STX1A,ADGRL3,ZEB1,TK2,TNS1,ZKSCAN5,FLRT2,LAT2,XRCC4,ZNF45,REEP1,FAM13C,TIGD6" Drug 3786_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "LTBP4,DOC2A,SLC4A4,ALDH7A1,ADGRB2,BCHE,BMP7,CBFA2T2,NRXN3,STOML1,AKAP7,IQCK,AKAP5,CRMP1,DAPK3,MFAP3L,CELSR3,ETV1,F5,FGF1,FGFR1,DCTN2,SIGLEC8,USP19,ZNF276,MSL3,MN1,NF1,NOVA1,NTRK2,PALM,PRPH,CCDC40,GAL3ST4,TCP11L1,SH3BP2,FAM214B,SMARCD3,UNC5B,DDN,ARC,WIPF1,SPHK2,NT5M,SLC17A7,KCNAB1" Drug 4629_UP Droperidol [548-73-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "KSR1,BMP7,SYNJ1,CACNA2D1,CALB2,KALRN,CAMK2B,FOXN3,SOCS6,CRMP1,ARHGEF10,KIAA0753,PLPPR4,EXOG,EDNRA,CNNM1,PLXNC1,RASGRP2,EZH1,DCTN2,PRELID3A,GNAL,GPD1,GRM8,BACH2,PACRG,MMP16,NF1,CNOT4,NOVA2,PDE4A,MTRF1L,FUZ,PREX2,ARHGEF40,SNCA,ARHGAP26,PHLDB1,COBL,TAL1,TCF4,DOCK9,DNAH7,VGF,DPF3,JPH3" Drug 2291_DN Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "RALGAPA1,NDRG3,NME5,BEGAIN,BIN1,APC,FAM131A,CFLAR,SYNJ1,SYNJ2,CFAP410,CLGN,CRLF1,SLIT2,AKAP7,GREB1,JAKMIP2,IQCG,GALC,SEPT9,GLYR1,GPD2,TDRKH,SPACA9,INPP5B,ADAM22,NF1,NPR2,SLC11A2,SLC25A23,SBF1,SH3BP2,SMARCA4,SNCA,ZBTB43,ELOVL4,KIAA1107,TMPO,ZKSCAN5,ZNF24,SPHK2,SLC30A3,DNALI1,EPM2A,PHTF2,SENP7" Drug 3579_DN Kaempferol [520-18-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AK2,DOC2A,CDC42BPA,APBA2,APC,CDC14B,PLA2G4C,CFLAR,SULT4A1,ABI3BP,ENTPD4,SH2B1,MFAP3L,LYPD1,EDNRA,ENO2,STX2,BAIAP2,FAM49B,GPR37,BTN2A1,KITLG,NEK1,NF1,NFYA,SLC11A2,PCDH9,NKAIN1,NLGN1,FAM214B,SLC6A8,CCDC88A,ELMO2,SPART,SS18,ST5,PCDHGA10,SLC44A1,TMPO,RUNDC3B,ZBTB14,REEP1,EVI5,URM1,KAT6A,AAAS" Drug 4177_DN Gelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ADORA2A,BIN1,APC,FAM131A,MARK4,ALDH7A1,NRP2,ARHGEF1,SEPT7,CLTB,LY86,WHRN,SNCAIP,GREB1,TMCC2,EXOG,PLXNC1,ELN,VPS13B,IGSF6,DLC1,FHL1,SEPT9,ALDH1L1,LYVE1,GRIK5,GSN,ZNF862,NF1,SERPINI1,RIPOR1,RNASEL,MAP6D1,SBF1,ZNF821,PEX26,SNCA,IQSEC2,ZBTB43,THSD1,ARC,ZEB1,KAT6B,TNS1,XRCC4,SPHK2" Drug 3781_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "LTBP4,DOC2A,EPB41L5,GAS7,ALDH7A1,BMP7,HAP1,CBS,ARHGEF1,PLAA,ABCG2,IQCK,HAPLN1,SEC14L5,MFAP3L,DUSP9,EDNRA,ETV1,DCTN2,CGREF1,CSPG5,OGA,ICA1,IL12A,ZNF862,NELL2,NF1,NOVA1,PCDH9,PRKAB2,GAL3ST4,RGS4,KCTD17,TCP11L1,DZIP1,ZNF334,UNC5B,ATP10B,TBCEL,TRIM2,TIMP4,TPM1,VGF,VLDLR,MPPE1,DPF3" Drug 5518_UP Carbamazepine [298-46-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ABR,C1QTNF1,BIN1,AMT,CDC42BPA,AQP6,PLA2G4C,CFLAR,LDLRAD4,CACNB4,HAP1,KCNAB3,TAOK2,C2CD2,VCAN,RIMS2,RASSF2,DGKG,SLC12A6,AASS,FGF13,AGAP2,NSG1,SIGLEC8,GPR162,RUNDC3A,RASSF8,KCNB1,LAMA2,NF1,WDR25,ELOVL2,CCDC25,CCDC102B,RPS6KA2,SBF1,ZFP2,PKNOX2,CCDC88A,KDM4C,PEG10,KIAA0930,CRTC1,TK2,VSNL1,PLSCR4" Drug 3174_DN Vinpocetine [42971-09-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASPHD1,ABHD6,ALCAM,TRMT9B,APBB2,APOC1,SEMA4G,ARRB2,MARK4,ATP6V0A1,RIPK1,SCAPER,MTMR2,CFAP410,KYAT1,ARHGEF1,CREM,PDE4DIP,CTH,CYBB,VPS13B,COQ7,VPS26C,ANKMY1,FGFR1,USP19,HNMT,KHK,MEIS2,NFYA,CNOT4,ZNF821,FUZ,KIF13A,SOX3,UNC5B,MCF2L,PCDHA6,ZNF34,TK2,ZKSCAN5,MAP3K12,HPS4,MPPE1,EPM2A,IFT88" Drug 2305_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG2,FAM135A,TRMT9B,CDC42BPA,SPTBN4,DNAH17,ATP6V0A1,BACH1,NRP2,CALB2,CAMK2B,CAMK2G,CDH2,CACNA2D2,CLCN3,AATK,LRRC17,NRN1,OLFM1,FGFR1,GRM8,IRAK3,C2orf72,KCNB1,KCND1,L1CAM,MN1,NPTX2,OGG1,PDE4A,PLCD1,PDZRN4,RELN,CCDC40,RASGRF1,SBF1,ASAP3,LIMCH1,SNCA,HECW1,SPTB,ZBTB43,TROVE2,TNS1,CLIP2,DNALI1" Drug 4408_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ALCAM,AMPD3,APC,APLP1,CDK10,MTMR3,CA4,CBFA2T2,CLCN3,CSNK1E,RIMS2,DBN1,EXOG,SLC12A6,OPTN,ERCC2,FGF13,FGFR1,BAIAP2,PDLIM5,KHDRBS3,GAD1,SEPT9,SRCAP,RUNDC3A,GNG4,CNTRL,GRM8,TJAP1,IL6ST,KCNH2,KHK,ADAM22,LRP12,MAPK7,CNNM2,ZDHHC14,EMID1,ASAP3,SLC9A5,PDZRN3,PHLDB1,TIAM1,VLDLR,SPHK2,EMSY" Drug 5993_DN Proxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "APOC1,PDE8B,ATP6V0A1,CFLAR,CBFA2T2,TAOK2,PLAA,AKAP7,SH2B1,CNTNAP2,GIT2,MFAP3L,CDON,TOM1,MRNIP,SCML2,ZNF589,FGFR1,MALT1,COPS8,TDRKH,GRB10,IL6R,IL6ST,KCNF1,MIA2,ZNF862,NF1,PRKAR1B,PRODH,CNNM2,RIPOR1,RAD51D,ROBO1,NEK11,FBXO11,SNCA,IQSEC2,PLCB1,TRIM2,TNS2,VLDLR,LMF1,XRCC4,MAP3K12,GDPD5" Drug 4240_UP Letrozole [112809-51-5]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG2,PKP4,PRX,ZSCAN18,ATP6V0A1,ADGRB3,BMP7,RUNX1T1,CNTN1,PDE4DIP,PHF14,NCALD,ABCA8,TRMO,SYT17,NEU3,SRCAP,PCDH17,LILRA2,GRIK5,ATXN2L,KIT,SMAD1,MAN2A2,MARK1,MMP16,NF1,NRCAM,NTRK2,PDPK1,MINDY2,MARCH1,ZMAT4,FBXO11,ZNF334,SNCA,FAIM2,ZHX3,SPP1,SPTB,LMO3,SYN2,ASTN2,TAL1,KCNAB1,PHTF2" Drug 5809_UP Natamycin [7681-93-8]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "APOC1,PPP4R4,SLC4A4,ALDH7A1,CFLAR,KSR1,BMP7,CCNT1,LARGE1,CRLF1,TAOK2,SH2B1,GIT2,CDON,AASS,IRAK4,MRNIP,RASGRP2,FCGRT,FGF12,SEMA4D,SEPT9,IFI16,PACRG,MAN2A2,MAPT,KITLG,MPP2,LRP12,PPP1R1A,PPP5C,PTPRE,ZCWPW1,BEND5,GSTCD,RTN1,ABLIM3,PKNOX2,COA1,SMARCA4,TMCC1,CEP68,DOCK9,SLC44A1,SPHK2,TFIP11" Drug 7287_DN Trichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AP2A2,NCOA1,CFLAR,ST3GAL5,HIP1R,BAG4,CSNK1E,PPP6R2,ARHGAP32,SGSM2,F8,SCARA3,DLL3,SRCAP,GFER,MAP4,NF1,NFYA,SLC11A2,PLCD1,SMIM7,PRKAB2,PTN,MCMBP,SAFB,MAPK12,SBF1,FAM102A,PEX26,EPN2,KBTBD4,BTBD7,LIMCH1,TMCC1,SPATA7,CDK19,PDLIM2,IQCE,FBXW11,PARD3,ZKSCAN5,HIRA,XRCC4,EVI5,FIP1L1,RNF170" Drug 7258_UP Aminocaproic acid [60-32-2]; Up 200; 30.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "AMH,APC,MARCH3,SLC4A4,ALDH7A1,CFLAR,CACNA1G,MYRF,LDLRAD4,SCARB1,NRXN3,VCAN,DZIP3,TBC1D5,DPH1,MTSS1L,ANKMY1,ST3GAL6,FYB1,TMEM8B,CRCP,GLI2,ATXN2L,KCNJ5,MITF,CLDN11,PALM,PRKAB2,PRKAR1B,TMEM231,GTDC1,SUGCT,KIRREL1,RXRA,MAPK12,MYH15,TMCC1,SPTAN1,ARC,RPGRIP1L,SZT2,TK2,CABIN1,WNT7A,ACTR3B,IFT88" Drug 5252_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ASIC1,MARK4,ADAM23,MTMR3,CAMK2B,AKAP5,CREM,ARHGEF4,DAPK1,DTNA,HEYL,EGR3,MTSS1L,F5,OLFM1,SCARA3,FUT9,DISC1,SRCAP,POLL,GNAO1,PRUNE2,GRB10,GSTM5,SYNPO,KCNN1,MID1,ADAM22,MX1,SERPINI1,PLTP,RIPOR1,C1orf54,NLGN1,PKNOX2,ZNF415,ZHX3,ZSWIM8,ERC1,ZNF423,SPTB,ZBTB43,TSPYL2,DMXL2,UGT8,LAT2" Drug 7358_UP Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "DOC2A,BIN1,AMT,BCAS1,DNAH17,CFLAR,CRLF1,CBARP,B4GALT6,WHRN,NCOR2,FAM169A,SNPH,MRNIP,STX2,AFF2,DISC1,PRUNE2,CNTRL,RNFT2,RASSF8,ATXN2L,ELOVL5,HNMT,MAPT,MITF,ADAM22,LYRM9,NPTX1,OGG1,TMEM104,ZSCAN2,RGS12,PBRM1,TCP11L1,SBF1,SYBU,LIMCH1,RBM34,SOX3,FNBP1,HECW1,ZBTB43,RBM26,PCDHA5,CHST8" Drug 255_DN dexamethasone; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG2,C1QTNF1,APAF1,NRP2,SYNJ2,BAIAP3,ENTPD6,ARHGAP33,CLCN3,CNR1,C2CD2,HINFP,NCOR2,AATK,RIMS2,EXOG,OPTN,FAM13A,MBNL2,RGS17,STX2,VPS26C,SMC2,CAMKK2,MALT1,LILRA2,RNFT2,ADAMTS6,ITPKB,AFF1,FXYD1,PLXNB1,STUM,SUPT20H,AMBRA1,CDK5RAP2,KDM4B,SPTAN1,SPART,CLSTN2,PHLDB1,EXOC7,TSC2,ZNF184,GDPD5,MPPE1" Drug 4796_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ATP6V0A1,CFLAR,SGCE,CACNA1G,CFAP410,KALRN,SCARB1,RCBTB2,FOXN3,PLEKHB1,RAB28,CTH,RIMS2,GIT2,ALDH1L1,RAB40B,GPER1,GRB10,GRIK5,GRM8,TJAP1,KCNN1,MBNL1,ADAM22,NF1,P2RY1,PLCD1,LRRN3,C1orf54,GSTCD,FBXW7,SATB1,HSPA4L,SH3BP2,SLA,FAIM2,NXT2,PHLDB1,EXOC7,WSCD1,TRIM2,DOCK9,ZBTB14,SLC30A3,SLC17A7,RNF146" Drug 2934_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "ABHD6,BIN1,CFLAR,CACNA1I,RUNX1T1,CBFA2T2,SYNGR3,ARHGAP33,B4GALT6,TAOK2,EPS15L1,CNTN1,CREM,DBN1,EDNRB,CELSR3,FAM13A,MRNIP,KAT8,BAIAP2,FYB1,SEPT9,ITPKA,KHK,KIFC3,SCAMP5,ZNF862,NINJ2,NPTX1,NTRK2,PDE4D,DUSP26,SLC25A23,PPARA,PTPRN2,GTDC1,ZNF821,HKDC1,CCDC88A,IQSEC2,IQCE,VIPR2,LMF1,CLIP2,WNT7A,MKRN3" Drug 387_UP "estradiol, USP; Up 200; 0.01uM; HL60; HG-U133A" Broad Institute CMAP Up 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "NDRG3,NDRG2,DNAH17,RASL11B,SLC4A4,ADGRB1,CA12,SLC25A14,ENTPD6,KCNAB3,LARGE1,DLGAP1,CLTB,RAB26,CRYM,GIT2,EPHB1,BAIAP2,SEC23B,TRMO,INPP5K,NEU3,CACFD1,AP4S1,PADI2,L1CAM,MX1,SLC11A2,OCRL,PDCD2,PLCB2,PRKAR1B,MAPK3,DPF2,SGK1,SHMT2,SNAP25,KDM4B,UHRF1BP1L,SPART,STX1A,KAT6B,VIPR2,WNT7A,KCNAB1,MPPE1" Drug 2324_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.36E-06 5.94E-02 6.53E-05 7.35E-04 46 197 "LTBP4,AMPD3,APOC1,CDK13,SLC4A4,CACNA2D2,SLIT2,BAG4,CREM,DOCK4,DTNA,TOM1,CNNM1,EIF4G2,HSD17B14,FECH,FHL1,ANKFY1,PRELID3A,B4GALNT1,ERAP1,TXNL4A,MSL3,GNG4,SPACA9,KCNN1,KCNN2,KIF2A,TM6SF1,NEK1,RETREG1,PRKAR1B,PRODH,CNNM2,ELOVL2,EPN2,SPTAN1,ELOVL4,PLCB1,SYN2,ZNF34,THRA,VLDLR,ZNF45,REEP1,EVI5" Drug CID000000197 AdPK Stitch 1.39E-06 6.08E-02 6.66E-05 7.51E-04 235 1548 "CLK4,ACTN1,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,AGT,NME5,AK2,TAOK1,ALK,MAP4K3,MYH7B,APAF1,APC,CDK10,CASK,ARRB1,CDK13,STK33,MARK4,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,RIPK1,KIF1A,BMPR1B,BTK,AP1M1,DDR1,CALM1,CAMK2A,CAMK2B,CAMK2G,CCNH,P2RX6,CD38,ENTPD2,DGKI,CDC25B,DCLK1,ASIC3,TAOK2,MYL6B,CLTC,CNTN1,CPS1,ABCG1,CS,CSF1R,CSNK1E,CSNK1G3,ZFYVE16,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DCTN1,DMD,DMPK,DNM1L,E2F5,EDN1,HIPK3,EGFR,EIF4G1,EIF5,IRAK4,TNK2,ENO2,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,KATNAL1,F5,F8,TUBA1B,PTK2B,TUBB3,TAOK3,STRADA,PPP1R1B,FER,FGF1,FGFR1,FGFR3,PRKAG2,ATP5PD,IP6K2,VTI1B,FOXO3,FLT1,DCTN2,AK8,TPK1,CAMKK2,ATP6V1H,ATP2C1,CELF1,BRSK1,FYN,IP6K3,IQGAP2,MTHFD2,ACSS1,GCK,GGT7,GGT5,MALT1,TTBK1,DBF4,GLUL,DCLK2,GPD2,LPAR4,CIT,GSN,MAP4K5,IRAK3,DDX19B,HMGCR,MYLK2,ITGAM,ITPKA,ITPKB,JAK2,KHK,KIF5A,KIT,SMAD1,MARK1,MARK3,MAT2A,MATK,MEF2C,AFDN,MYH3,MYO5A,MYO6,MYO9A,P2RY13,NEK1,NME4,NTRK2,NTRK3,KSR2,P2RX7,P2RY1,CDK18,PDE4B,PDE4D,PDPK1,PFKFB2,PFKFB3,PFKFB4,ABCB1,PIK3C2A,PIK3R1,ZNF655,PKM,PLCB2,PLIN1,POLR2F,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PRPSAP2,SNRK,PTK2,ACSS3,RAD17,RET,RNASE1,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,RPS20,HUNK,MAPK12,CASC3,SGK1,MYO18A,MAST1,FNBP1,NMNAT2,PEG10,CDK19,NEK4,TTBK2,SYT1,TAF6,MLST8,TAF9,CLASP1,TEK,TK2,ACTR6,TLR4,CABIN1,TPM1,CDK20,NPL,TPM2,TSC1,TSC2,SGK3,TUBB1,UBC,P2RY12,RICTOR,SPHK2,MAP3K12,TUBA1A,WNK3,WNK2" Drug ctd:D015124 8-Bromo Cyclic Adenosine Monophosphate CTD 1.46E-06 6.40E-02 7.01E-05 7.90E-04 120 693 "AGT,ADGRF5,ABCD2,OGT,MYH7B,APAF1,APC,N4BP2L1,DOCK11,CFLAR,CABP7,CARS,RUNX1T1,SCARB1,ARHGEF2,CLGN,CHN1,NGEF,FAM19A5,SULT4A1,CNR1,AKAP7,WHRN,NECTIN3,CRHBP,ABCG1,PHACTR3,ARHGEF4,RIPOR2,DGKB,SPOCK2,BRINP1,ARMCX4,PITPNC1,LYPD1,RHOBTB1,GRIN3A,NR1D2,CDON,KLHL5,EGFR,HSD17B14,LRRC17,STX2,ETV1,ST3GAL6,FDFT1,FGF13,FOXO3,ABLIM2,GABRG1,IQGAP2,ERAP1,GCK,STARD3,GPR37,GRB10,LINGO1,ADAMTS6,HAS2,HLF,HNF4G,IGF1,ITPKB,KCND2,LSS,MAPT,MIA2,MMP16,NCF2,NRCAM,PCSK1,PDE3A,GNG2,SERPINI1,SMOX,PSAT1,PPARA,MAPK3,MAPK10,PTK2,PTPRE,PID1,ENOX1,SLC25A36,ROBO2,RORB,RYR3,TNFRSF19,MRAS,SGK1,LIMCH1,SNCA,PDZRN3,DOK5,SPP1,UNC5B,PEG10,LMO3,NUDT10,PLCB1,MCF2L,CUX2,TRIM2,SYNE1,PCDHB4,SIRT1,CDH22,THRA,TPM1,ANKRD20A2,FAM155A,OSBP2,VGF,VLDLR,LAT2,PCDH20,CADM2,NAV3,MSRB3" Drug 6085_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.54E-06 6.74E-02 7.19E-05 8.10E-04 42 174 "NME5,APLP1,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,FAM13A,RASGRP2,FYN,CYP46A1,RAB40B,STON1,PCLO,KCNH2,MPP2,MXI1,NEK1,SERPINI1,PRPH,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,WDR47,ARHGEF40,PEG10,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,GPR161,HEY1,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug 1664_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-06 6.89E-02 7.19E-05 8.10E-04 44 186 "NDRG2,AMPD3,APBB2,MARK4,CFLAR,HIP1R,PLEKHB1,SH2B1,CSNK1E,GPRASP1,GIT2,LYPD1,FCF1,ING4,EXTL2,EZH1,INPP5K,RAB40B,TDRKH,STON1,LMO2,ZNF862,RETREG2,PTCH1,PTPRE,CCDC25,PCMTD2,EMID1,FNDC3A,KDM3A,CDK19,THSD1,CEP68,TACC1,TRIM2,SZT2,FRYL,TK2,BEX4,VGF,SPHK2,EMSY,MPPE1,UBE3B" Drug 4601_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASPHD1,C1QTNF3,GAS7,DNAH17,MTMR3,CACNA1I,CACNA2D1,KRIT1,ARHGEF2,CPS1,CREM,CRY2,PDE4DIP,SPOCK2,GIT2,C2CD2L,PARD6A,DTNA,SRPK3,MTSS1L,ETV1,REEP2,TRMO,LYVE1,TDRKH,ATXN2L,ITGA7,MIA2,NPTX1,P2RY1,PDE4B,VPS13C,PTPRB,PTPRN2,TMEM231,ACSS3,FBXW7,SH3BP2,FBXO11,SNCA,UNC5B,SS18,SYN2,TIMP4,HIRA,DPF3" Drug 5075_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "SEMA7A,ARHGDIG,ADGRB2,NRP2,LDLRAD4,CALB2,RUNX1T1,CHN2,CHRNA4,NRXN3,WHRN,RGS6,CSNK1E,PDE4DIP,CDON,DUSP9,TNK2,MRNIP,MTSS1L,DLC1,FAM49B,SIGLEC8,LYVE1,GPD1,RASSF8,HLF,AFDN,ADAM22,NRCAM,PALM,RETREG1,GRAMD1C,ZSCAN32,PID1,ZMAT4,RGS12,TCP11L1,ST6GAL1,SNCA,ATP10B,DOCK9,THRA,R3HDM1,RPRM,SEMA3B,FAM13C" Drug 2108_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASIC1,SEMA6A,ALK,KCNAB2,LGR5,CACNA1I,CAMK2B,CBFA2T2,SCARB1,LARGE1,CHRNA4,ARHGAP22,CRY2,C2CD2L,GPR162,GLYR1,TOX3,KCNMB4,GNAL,GNAO1,LPAR4,ITGA7,SMAD1,GIT1,MT1M,NF1,P2RY1,ENPP2,PPARA,LRRN3,PPP5C,PRPH,ZCWPW1,MRAS,ZNF334,MYH15,SNAP25,ZHX3,SAMSN1,ADGRL3,THRA,VIPR2,WIPF1,NT5M,NLRP3,GAN" Drug 4254_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "RALGAPA1,AMPD3,KIF1A,ADAM23,CFLAR,BAIAP3,CFAP410,CACNA2D2,ARHGEF10,CNTNAP2,CNNM1,EGFR,PLXNC1,AFF2,PRELID3A,CSPG5,FYB1,INPP5K,ALDH1L1,RUNDC3A,TXNL4A,GLYR1,HNMT,MAPT,NOVA2,PDE4B,PLXNB1,PPARA,GRAMD1C,ELOVL2,PTPRB,PTPRH,ZSCAN2,KANSL3,SNCA,KIF13A,RBM34,TSNAXIP1,IQSEC2,TROVE2,KIAA1107,SPHK2,KCNAB1,PARP11,FAM13C,TIGD6" Drug 4414_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASIC1,LTBP4,AMPD3,ARHGDIG,ADGRB3,GYG2,CFAP410,CALB2,CDH2,RAB33A,COL9A3,GSDME,DOCK2,ECM2,HEYL,SPEG,PIPOX,F5,ZNF589,OLFM1,AGAP2,GAD1,NEU3,HPGDS,ADAMTS13,GRIK5,IRF8,ITGA7,KIFC3,ADAM22,MX1,PALM,PCDHGC3,CDK18,CEP41,PTX3,MARCH1,KHDRBS2,ZMAT4,CPEB3,SLC6A8,PEG10,LAT2,SLC17A7,ITM2C,DPF3" Drug 3725_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "LTBP4,ALK,ARHGDIG,NRP2,CFLAR,FUBP1,CBS,CLDN10,USP2,NCOR2,PDE4DIP,RIMS2,MFAP3L,DMPK,DTNB,ECM2,SEMA3D,RASGRP2,PIPOX,AGAP2,RUNDC3A,LILRA2,GRM8,KCNN2,MMP17,LYRM9,MYT1,NTRK3,PPP2R2B,PTH1R,ZMAT4,SALL1,ZNF821,STUM,CPEB3,CNKSR2,PKNOX2,FAIM2,ZSWIM8,HECW1,ZC3H13,SYT5,SLC44A1,FLRT2,LAT2,REEP1" Drug 2538_DN Sulfapyridine [144-83-2]; Down 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "NDRG3,CDK10,CDK13,SLC4A4,ADAM23,ADAM15,C5,CAMK2G,NFS1,KYAT1,FOXN3,HOMER3,BAG4,CPS1,SH2B1,VCAN,DAPK3,RUSC2,CDON,F8,ZNF589,GAA,ZNF44,INPP5K,ACOT7,ICA1,ITPKB,MAP4,NF1,NFYA,PIK3R1,NLE1,ZDHHC14,GTDC1,GSTCD,TRAPPC13,GALNT10,PPP4R3A,BTBD7,ZBTB43,SS18,SZT2,THRA,KAT6B,FLRT2,EPM2A" Drug 3527_UP Iopanoic acid [96-83-3]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "BRAP,APLP1,SCAPER,CACNA1I,BAIAP3,ARHGAP33,CACNA2D2,FOXN3,PLEKHB1,RCHY1,VCAN,SOCS5,PHF14,GREB1,SEC14L5,DUSP9,FCF1,VPS13B,ANKMY1,DLC1,ST3GAL6,FGFR1,TMEM8B,MALT1,LYVE1,SOX21,ICA1,LIG4,AFF1,ADAM22,MSR1,PPP2R2B,PPP5C,GRAMD1C,RGS12,TCP11L1,TRA2B,CXXC4,SYT5,SZT2,DOCK9,R3HDM1,AMACR,XRCC4,ZFP37,TIGD6" Drug 6019_DN Quinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "TRMT9B,APBA2,APLP1,FAM131A,NUMB,SLC2A11,ATP6V0A1,MTMR3,CBFA2T2,AP4M1,ARHGAP33,EPS15L1,HOMER3,AKAP7,CREM,ENTPD4,CNTNAP2,GIT2,MFAP3L,CDON,TSPAN5,TRAF3IP2,MSL3,CNTRL,DIDO1,GRM8,ITPKB,IPO5,MPP2,TAGLN3,NF1,NPR2,MINDY2,PTPRE,RNASEL,CEP68,TTBK2,ARC,SATB2,TRIM2,CRTC1,CHST8,TPM1,VAV1,VIPR2,XRCC4" Drug 2171_UP Deltaline [6836-11-9]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "SYN3,NDRG2,SRPX,ALK,CDC42BPA,APBB2,PDE8B,ADGRB1,MTMR3,THSD7A,MAGI1,B4GALT6,TAOK2,CABP1,NRG2,PDE4DIP,RIMS2,MYEF2,HIPK3,PLXNC1,C3orf18,ERBB2,TMEM8B,ALDH1L1,POLL,STON1,KCNN1,MBNL1,MPP2,NTRK2,PFKFB4,PLCL1,SUSD4,RASGRF1,SEMA6D,EPN2,PKNOX2,LHPP,TACR1,LMF1,KLC2,MAP3K12,GDPD5,PRDM10,FAM13C,JPH3" Drug 3330_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "AP2A2,C1QTNF1,APOC1,RGS20,RGS11,HAP1,CAMK2B,RUNX1T1,CCK,WHRN,CNTNAP2,RIMS2,SPOCK2,RCAN2,REEP2,FAM198B,AGAP2,AFF2,GAD1,DISC1,RUNDC3A,TDRKH,IRF8,KCNQ3,ZNF862,PCBP3,PLCB2,PLTP,LRP12,KLHL11,KCNIP1,STUM,ASAP3,ST6GAL1,PKNOX2,SOX3,PEG10,ZNF423,ZC3H13,DOCK9,SLC19A3,ICAM5,TRPM2,ITM2C,PARP11,DPF3" Drug 4013_UP Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADD2,AMPH,APBB2,PPP4R4,ARSE,AZGP1,CFLAR,SCAPER,MTMR3,LDB2,SCARB1,TAOK2,TPP1,ENTPD4,SUSD5,SEC14L5,DTNA,HIPK3,CELSR3,EIF4G2,ZNF391,HPCAL4,PRELID3A,GRIK5,CACFD1,GSTM5,KCNN1,MMP16,NEFM,NF1,NTRK2,PPARA,LRRN3,MAPK4,BEND5,ZMAT4,CSRNP3,CNKSR2,SLA,SLC11A1,OGDHL,ZSWIM8,EXOC7,R3HDM1,TNS1,PHTF2" Drug 7224_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADORA2A,NME5,SPARCL1,APBB2,ARRB1,PLA2G4C,ATP6V0A1,ST3GAL5,BAIAP3,CA12,CAMK2B,USP2,CD86,ARHGEF2,STOML1,AKAP12,NCOR2,ARHGEF10,RASSF2,JAKMIP2,EDNRA,MBNL2,SPEG,KAT8,FGFR3,KHDRBS3,OGA,FYB1,ERAP1,POLL,GRIN2C,IL6R,IL6ST,INPP5B,MITF,MYCN,MYT1,NECAB2,CRTAC1,ZFP30,FRMPD1,PREX2,FAM214B,RGL1,PHLDB1,R3HDM1" Drug 3743_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "C1QTNF3,ALK,SLC4A4,ALDH7A1,IL33,LARGE1,STOML1,FAM189A2,ARHGAP24,PARD6A,DMPK,DTNA,EIF4G2,PDLIM5,USP19,RAB30,KCNMB4,SCIN,KCNJ5,MAP2,MAPT,NDP,NELL2,NF1,PCBP3,PFKFB2,PPP5C,CEP41,PRPH,WDR25,PTCH1,C1orf54,SUSD4,BEND5,ZNF821,SLC9A5,SLC14A1,BTBD7,SZT2,DNAH7,TNS1,HIRA,ZNF24,SPHK2,REEP1,KCNAB1" Drug 3219_DN Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "RGS20,MARK4,HOMER3,ARMC8,DCAF8,EDNRA,ANKMY1,EZH1,KAT8,BAIAP2,FHL1,MPP6,POLL,RNFT2,HSF2,KIF2A,LIG4,GIT1,ADAM22,NFYA,CNOT4,PCDH9,PLEC,ROBO1,NEK11,MCMBP,AMBRA1,KBTBD4,ELMO2,BTBD7,COA1,CDK5RAP2,KDM4B,KDM4C,TROVE2,CEP68,STX1A,PLCB1,MTCL1,KAT6B,HIRA,PLPPR2,VAV1,SEMA3B,MPPE1,SMIM8" Drug 1523_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASIC1,AMPD3,BIN1,CDC42BPA,SEMA7A,APOC1,MARK4,NUMB,ALDH7A1,SCARB1,AKAP6,CSF1R,PYGO1,RIPOR2,RASSF2,SPOCK2,OPTN,BAIAP2,INPP5B,KCNQ3,SMAD1,MAPT,MYCN,NF1,NNAT,SLC11A2,PALM,PCDH9,PDE4D,PFKFB2,LRP12,PRODH,ZSCAN32,CEP97,RFX2,ZFHX4,KCNIP1,SH3BP2,ZNF423,TROVE2,SYT5,TBCEL,SMG6,SZT2,HIF3A,TRIO" Drug 2634_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADD2,ADORA2A,AP2A2,GAS7,N4BP2L1,ATP6V0A1,BAIAP3,CA4,ARHGEF1,MAGI1,TAOK2,ABI3BP,RCHY1,PDE4DIP,MFAP3L,OPTN,DENND4A,NCALD,PTK2B,FGF1,SEMA4D,GAD1,SIGLEC8,GLYR1,GRB10,ATXN2L,ICA1,INPP5B,KCNN2,ADAM22,MSR1,PLCD1,PPP2R2B,SAMD9,CCDC40,RGS12,GSTCD,FAM214B,PKNOX2,SLC9A5,IZUMO4,SMG6,METTL3,WIPF1,PHTF2,AP3B2" Drug 2845_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ABHD6,NDRG2,ADCY6,AP2A2,NME5,KCNAB2,APBB2,APC,PPFIA3,PLA2G4C,CA4,CSF1R,CTH,ERCC2,TBC1D16,FGFR1,BAIAP2,GAD1,SRCAP,INPP5B,KCNH2,SMAD1,MIA2,ADAM22,ZNF862,NF1,PALM,PCDH9,PFKFB2,LRP12,PPP5C,CEP41,MAPK7,RGS12,STUM,ASAP3,PEX26,SLC9A5,SOX3,TSNAXIP1,SZT2,DICER1,TK2,NR2C2,ZKSCAN5,GDPD5" Drug 6306_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "NME5,ALK,SLC4A4,ATP6V0A1,CFLAR,CFAP410,CBS,ARHGEF1,DLGAP1,HOMER3,IQCK,WHRN,DUSP9,HIPK3,MBNL2,PLXNC1,EIF4G2,FGFR1,BAIAP2,HPCAL4,IQCG,TRMO,ZNF276,POLL,GNAO1,GPD2,SPACA9,PTPRT,NXPH3,ITGA7,KCNF1,NF1,CNOT4,STRN3,KIRREL1,PEX26,TMCC1,ZHX3,PHLDB1,DNAH7,TK2,TLR4,LMF1,ZNF74,KCNAB1,UBE3B" Drug 6517_UP Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "GAS7,CFLAR,SYNJ1,SYNJ2,CAMK2G,PLEKHB1,TAOK2,TPP1,HOMER3,AKAP7,MAML1,BRINP1,DMPK,DTNA,EDNRA,FAM13A,MBNL2,FER,ERAP1,ALDH1L1,GPER1,GRB10,GSTM5,SHISAL1,KCNN1,LIG4,MEF2C,MMP16,MSI1,CNOT4,RETREG1,MTRF1L,RELN,KCTD17,GSTCD,SNAP25,SNCA,PLCB1,ZEB1,TRIM2,TRPM2,VIPR2,LAT2,XRCC4,PHTF2,JPH3" Drug 6976_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "NDRG2,BIN1,APAF1,APOC1,MARK4,ADGRB2,MTMR3,ARHGAP33,PDE4DIP,DZIP3,CTH,GREB1,GPRASP1,SNPH,MED12,DTNA,EIF5,TNK2,ENO2,ZNF589,FGF12,GAA,GLYR1,INPP5B,ITPKB,LMO2,LSS,MAPT,MPP2,GIT1,ADAM22,PALM,ZSCAN32,GTDC1,ATXN7,SLC6A8,ZBTB43,VPS13A,PLCB1,TNS2,ICAM5,VIPR2,LAT2,KCNK12,ZFP37,HPS4" Drug 2623_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "TRMT9B,AMPH,BIN1,APBA2,GAS7,MARK4,ADAM23,GYG2,CA4,CAMK2B,TAOK2,NRG2,CSF1,PDE4DIP,SPOCK2,MFAP3L,C2CD2L,GSDME,EXOG,ELN,C3orf18,HSD17B14,VPS13B,RASGRP2,FAM198B,GABRG2,GCNT2,GSTM5,INPP5B,ITPKA,PCDHGC3,PTPRN2,SBF1,SMARCD3,KDM4C,ZC3H13,CLSTN2,ST5,SMG6,SYNE1,AP4E1,TUBB1,WIPF1,LAT2,ADAMTS9,SEMA3B" Drug 4492_UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "NDRG2,C1QTNF3,APAF1,BCAS1,CDK13,ATP1A3,CFLAR,FUBP1,STOML1,QKI,CNTN1,WHRN,COL9A3,CPS1,NCOR2,CSF1,CTH,EXOG,DTNA,EDNRB,MBNL2,STX2,REEP2,FGFR1,FAM49B,OGA,JAK2,LAMA2,AFDN,MMP17,ADAM22,NF1,NTRK2,PDE4A,STRN3,MINDY2,PPP2R2B,ZSCAN2,RBM34,DOK5,SP4,ARHGAP26,TRIO,TRO,VAV1,EVI5" Drug 5738_DN "Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "AP2A2,CDC14B,PPP4R4,CA8,SOCS6,ASIC3,B4GALT6,PDE4DIP,HDAC4,RHOBTB1,CDON,TENM1,FER,CGREF1,OGA,ZNF276,GNG4,TDRKH,GPER1,GPR37,DHX35,IL12A,KCNH2,MAPT,GIT1,MX1,ZNF862,CLDN11,POLG,PRKAR1B,TMEM231,ASAP3,AMBRA1,PEX26,SLC14A1,SMARCD3,SNCA,CEP68,EXOC7,DNAH7,GPR161,HIRA,VGF,NDRG4,EMSY,TIGD6" Drug 4095_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "C1QTNF3,CDC14B,CACNA2D1,CAMK2B,SLC16A4,DGKI,CACNA2D2,NRXN3,CNTN1,NCOR2,CSF1R,IPCEF1,ARHGEF4,RIMS2,SEC14L5,SPOCK2,C2CD2L,SPOCK3,DTNA,EDNRA,SRPK3,IGSF6,CORO2B,FGF1,GABRB3,SRCAP,STMN2,KCNF1,KCNJ5,KCNN1,KITLG,NF1,NPTX1,NTRK2,PLCD1,PPARA,MAPK10,RGS4,ZNF821,NLGN1,CXXC4,FAIM2,KLHL4,PCDHGB6,HIF3A,CHST5" Drug 6352_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADORA1,SEMA4G,PPP4R4,STX16,NRP2,ST3GAL5,BAIAP3,CFAP410,CACNA1A,KALRN,CAMK2B,PLAA,AKAP7,ABCG1,PDE4DIP,EGFR,ERAP1,DISC1,GLYR1,MSL3,PRUNE2,ELOVL5,KCNJ5,MIA2,SCAMP5,NDP,CNOT4,RETREG1,POLG,FSD1,LRRN3,PRKAR1B,PTN,STUM,SLC9A5,ZNF667,IFT122,ZHX3,NSD1,CRTC1,OSBP2,VIPR2,XRCC4,UPF3A,KCNAB1,AAAS" Drug 4999_UP Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "APC,CDC14B,RGS20,SLC4A4,ALDH7A1,CFAP410,CAMK2A,SULT4A1,LY86,AKAP7,ABI3BP,PDE4DIP,EXOG,HS3ST2,CDON,PLXNC1,CDKL3,CORO2B,FHL1,GAD1,B4GALNT1,ALDH1L1,GCNT2,STON1,GRIK5,CACFD1,IRAK3,NXPH3,ICA1,SHISAL1,C2orf72,KCNQ3,P2RY1,PCDH9,MBOAT7,LRRN3,RGS3,SNCA,DOK5,PEG10,TACR1,PCDHGA10,THRA,KCNK12,NT5M,SEMA3B" Drug 4638_DN Dioxybenzone [131-53-3]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASIC1,TRMT9B,AMH,AMT,APOC1,PDE8B,ATP1A3,BAIAP3,KRIT1,B4GALT6,IQCK,CNTNAP2,SLITRK5,CHRDL1,DTNB,CELSR3,MBNL2,AASS,MRNIP,MTSS1L,FGFR3,CINP,SIGLEC8,ZNF276,COPS8,MSL3,GPD2,L1CAM,LIG4,NNAT,PTN,PTPRB,PTPRE,PID1,SLA,TSNAXIP1,KIAA1107,THRA,TK2,BEX4,TNS1,LMF1,ZNF711,SEMA3B,KAT6A,TIGD6" Drug 251_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ASIC1,KDM5D,NME5,ANK2,HIP1R,ARHGAP33,B4GALT6,LHX2,CNTN1,DPP6,EGFR,EIF4G2,COQ7,RCAN2,EPHB1,CDKL3,FGFR1,FGFR3,SRCAP,LILRA2,GRM8,SOX21,IRF8,C2orf72,IGF1,LAMP2,MEIS2,NELL2,NPTX1,MINDY2,CEP41,VPS13C,C1orf109,ROBO1,IFT122,SNCA,NMNAT2,SPP1,ZC4H2,KLHL7,NPL,UGT8,VSNL1,ZNF23,HPS4,MPPE1" Drug 7343_UP Moxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADORA1,ADORA2A,NME5,BIN1,ARRB1,RASL11B,BACH1,CFAP410,CAMK2G,CD86,CLGN,QKI,WHRN,CRY2,FAM169A,INTS1,DAPK3,GIT2,ZNF804A,DTNA,CNNM1,ING4,VPS13B,IGSF6,F8,OLFM1,FGFR1,PRELID3A,ALDH1L1,CNTRL,SPACA9,GRIK5,ATXN2L,IL6ST,MIA2,NF1,PTCH1,RIPOR1,FAM184A,RPS6KA2,ABLIM3,ARC,ANKRD12,FLRT2,KLC2,HPS4" Drug 1465_UP Troleandomycin [2751-09-9]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADORA1,SPARCL1,BIN1,KCNAB2,APBB2,APOC1,MARK4,ATP2B2,CFLAR,CACNA1I,CA4,HAP1,CD86,CDH2,CACNA2D2,PLEKHB1,WHRN,DMPK,EDNRB,IGSF6,ZNF589,FGFR1,TRAF3IP2,ALDH1L1,CACFD1,NXPH3,KCNH2,KITLG,ZNF862,CDK18,CEP41,PRKAR1B,FAM184A,SLC2A5,KIF13A,ARHGAP26,EXOC7,IQCE,CRTC1,TMEM121,TK2,CDK20,TRPM2,UCHL1,PDIA2,KCNAB1" Drug 3736_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "ADGRF5,C1QTNF3,TRMT9B,BIN1,CDC14B,ATP1A3,ATP2A2,ADGRB2,SYNGR3,PLEKHB1,STOML1,PICK1,DMPK,DTNA,PRELID3A,OGA,SIGLEC8,ALDH1L1,GLYR1,GRIK5,ITGA7,KIT,LMO2,MPP2,MT1M,NPR2,GPR85,PFKFB2,PIK3R1,RETREG1,WDR25,PTCH1,PTPRH,RNASEL,BTBD7,SNCA,ZNF415,DOK5,SOX15,SPTAN1,THSD1,PCDHA5,AP4E1,TK2,PIK3R5,REEP1" Drug 3639_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "LTBP4,BEGAIN,BIN1,APBA2,SEMA4G,SLC2A11,KIF1A,NRP2,CFLAR,BAIAP3,CACNA1A,SLC16A4,LRRFIP1,CRLF1,SLIT2,VAX2,AKAP7,AKAP5,CRY2,SNCAIP,PDE4DIP,CYBB,CGREF1,GAD1,ADAMTS13,SMAD1,MAP2,MATN3,MMP17,NF1,NPTX2,CDK18,RELN,PTPRO,ZSCAN2,GSTCD,CPEB3,CXXC4,SPTAN1,SPTB,KIAA0930,DOCK9,PCDHA5,SLC35G2,CHST8,FLRT2" Drug 7303_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "MTUS1,NME5,BIN1,PPFIA3,FUBP1,C5,RCBTB2,AKAP7,FAM131B,ARHGAP32,SNPH,GIT2,DBT,SGSM2,TMCC2,DYNC1I1,CDON,MAMLD1,BAIAP2,FYN,TXNL4A,CNTRL,MN1,GIT1,PCDH9,SH3TC2,MCMBP,RPS6KA2,KIF16B,BTBD7,SLC22A4,PDZD2,CLASP2,CAMTA2,ST5,PHLDB1,SUPT5H,VPS13A,TCF4,ZNF34,TNS1,HIRA,WNT7A,MAP3K12,NAV3,MPPE1" Drug 3928_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "KIAA1324,APAF1,N4BP2L1,CACNA1I,KALRN,CAMK2B,P2RX6,DCLK1,STOML1,LY86,SNCAIP,OSBPL3,CNTNAP2,C2CD2L,SPOCK3,DYNC1I1,DRP2,FAM13A,MTSS1L,ERCC2,CORO2B,DLC1,FGFR1,POLL,AP4S1,TJAP1,L1CAM,PURG,PPP2R2B,SAMD9,GAL3ST4,PKNOX2,SNCA,FAIM2,PDZD2,ZBTB43,JMJD6,DOCK9,CHST5,AMACR,UBE3A,FLRT2,ZNF225,SLC30A3,TIGD6,AP3B2" Drug 7304_DN Trolox [53188-07-1]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "C1QTNF1,APOC1,PPFIA3,CASK,EIF4G3,MPDZ,SCAPER,SRSF11,HINFP,DCAF4,ARMCX2,KIAA0753,LYPD1,DYNC1I1,FAM13A,ZNF589,SCARA3,ATP2C1,B4GALNT1,INPP5K,SESN1,CNTRL,SHISAL1,FAM69A,MBD1,MX1,PPP5C,MAPK3,BCAS3,GTDC1,KIRREL1,FBXW7,FAM102A,FUZ,AMBRA1,ANKRD6,BTBD7,COA1,SMARCD3,LIMCH1,DNMBP,ZNF34,R3HDM1,CABIN1,LMF1,WNT7A" Drug 6356_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "SYN3,ARRB2,ATP2B2,CFLAR,SYNJ2,ABCG2,SULT4A1,AKAP5,PDE4DIP,DTNA,EDIL3,EDN1,FAM13A,MBNL2,OGA,FYB1,PCDH17,GLYR1,KCNMB4,PRRC2B,RASSF8,IL6ST,ITGA7,KIF5A,MAPT,TM6SF1,MIA2,NF1,CNOT4,ENPP2,NECAB2,PREX2,SLC2A5,IFT122,CDK19,ZBTB43,PHLDB1,ADGRL3,KLHL4,TRIM2,ZFPM2,TRIO,NT5M,HRASLS,TIGD6,DPF3" Drug 7505_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "RALGAPA1,NDRG3,BRAP,LTBP4,CDC42BPA,APC,GAS7,APLP1,KIF1A,MTMR2,C5,CA12,CAMK2B,TAOK2,ABCG1,SOCS5,PDE4DIP,MED12,DTNA,PRELID3A,GAD1,GPER1,GRB10,ADAMTS13,RASSF8,ELOVL5,LMO2,MITF,SETD4,OCRL,PDE4A,SLC25A23,MBOAT7,TMEM231,SEMA6D,ZNF821,TROVE2,THSD1,ELOVL4,ARC,SMG6,SZT2,PCDHA6,VIPR2,ZNF189,EVI5" Drug 5492_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "AGT,ALK,BEGAIN,CDK10,ALDH7A1,AZGP1,CFLAR,MTMR2,CACNB4,HAP1,CNTNAP2,DMD,MBNL2,OLFM1,BAIAP2,IQCG,SYNPO,IFI16,KCNJ5,KCNN2,SMAD1,MATK,AFF1,AFDN,MSR1,MYT1,NFYA,P2RY1,PLCD1,PLEC,LRP12,PTCH1,CCDC40,ZDHHC14,SLC6A8,ELMO2,PDZD2,NMNAT2,CLSTN2,EXOC7,SMG6,PARD3,TNS1,SSBP2,KCNK12,KCNAB1" Drug 1493_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.90E-02 7.19E-05 8.10E-04 46 198 "AP2A2,SRPX,ALK,AMH,BIN1,CDC42BPA,APC,SEMA4G,SLC4A4,SCAPER,MTMR2,CAMK2B,KYAT1,TAOK2,CRMP1,RUSC2,SHANK1,EIF4G2,MRNIP,DLC1,FGFR1,ANKFY1,EFCAB2,PDLIM5,ALDH1L1,GPER1,INPP5B,KCNH2,MBD1,NACA,LRP12,MINDY2,PPP2R2B,PRKAR1B,SEMA6D,SLC22A4,IQCE,CRTC1,CHST8,CABIN1,PIK3R5,CDK20,WIPF1,ZNF45,KAT6A,SENP7" Drug 3332_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "ADRA1B,NME5,ALK,AMPH,AMT,MARK4,ST3GAL5,BAIAP3,CFAP410,USP2,PICK1,CRYM,PDE4DIP,CNTNAP2,DOCK4,TMCC2,CDON,EDIL3,REEP2,PTK2B,FGFR3,FHL1,FYN,CYP46A1,TDRKH,GRM2,TJAP1,ITGAM,MPP2,PDE4A,SERPINI1,PRPH,ZDHHC14,ZFHX4,RASA3,SH3GL3,ASAP3,PKNOX2,TSNAXIP1,RGL1,OBSL1,HEY1,FAM155A,SLC17A7,EPM2A" Drug 4269_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "MTUS1,ADAM15,CFLAR,SYNJ2,SCAPER,SPAG9,KRIT1,SRSF11,QKI,TBC1D5,DBT,ZBTB24,RHOBTB1,IRAK4,VPS26C,GAD1,INPP5K,HNMT,AGFG1,SHISAL1,IL6ST,MAP4,MIA2,OGG1,OPA1,PDE1C,PIK3R1,SNX10,STRN3,PRKAB2,PTN,RAD51D,SLC25A36,KIRREL1,SBF1,SEC14L1,PBLD,PLCB1,KIAA1107,DICER1,BHLHB9,EVI5,KCNAB1,UBE3B,FXR1" Drug 3976_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "ASIC1,AMPD3,BACH1,CFLAR,SCAPER,SGCE,CAMK2B,CNTN1,NECTIN3,SIPA1L1,CYBB,RASGRP2,ANKMY1,F5,KHDRBS3,FUT9,SYT17,PCDH17,RUNDC3A,ADAMTS13,KCNN2,NPY,PCDHGC3,CDK18,PRPH,PTPRD,RIPOR1,RGS12,FBXW7,TCP11L1,CPEB3,SLC9A5,ZHX3,THSD1,ARC,CRTC1,DICER1,TK2,VAV1,WIPF1,LAT2,SPHK2,SEMA3B,ITM2C,MPPE1" Drug 3858_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "ABHD6,NDRG2,APLP1,SEMA4G,CDK13,STX16,ADAM23,CFLAR,LDB2,USP2,SCARB1,CRY2,SNCAIP,DAPK3,BRINP1,EDN1,TNK2,C3orf18,ERCC2,SRCAP,GLYR1,HTATSF1,GPER1,GSN,IL6ST,ITGAM,JAK2,KHK,LSS,SMAD1,MEF2C,KITLG,MMP16,ADAM22,NEK1,TMOD2,SAMD9,RASA3,ST6GAL1,PPP4R3A,ARHGEF40,CDK19,FLRT2,CLIP2,ZBTB38" Drug 6684_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "AMH,PPFIA4,GAS7,ARHGDIG,ATP1A3,ATP2B2,ADGRB2,NRP2,LDLRAD4,CRLF1,CACNA2D2,CHN2,AKAP5,SUSD5,VCAN,MFAP3L,DTNB,EDN3,TNK2,CORO2B,FGFR1,AGAP2,SIGLEC8,GLUL,GRM8,SOX21,SHISAL1,KCNB1,LAMA2,SMAD9,MSI1,MX1,MYH3,DCHS2,TCP11L1,ANKRD6,PKNOX2,OGDHL,ZHX3,SPTB,DOCK9,PCDHA5,TLR4,TNS1,SENP7" Drug 3400_DN 2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "NME5,APBB2,APC,EPB41L5,APLP1,SCAPER,MTMR3,CFAP410,USP2,ARHGAP33,STOML1,PHF14,GIT2,MFAP3L,DTNA,HIPK3,FEM1B,VPS13B,STX2,SPEG,FGFR1,AGAP2,GLYR1,RAB30,HTATSF1,KCNMB4,IL6R,IL6ST,MMP16,ADAM22,NF1,NFYA,STRN3,POLG,EMID1,SGK1,CPEB3,FAM214B,KDM4C,PLCB1,TBCEL,TMPO,TRIO,FAM155A,PLPPR2" Drug 7542_UP Ald1.1-H_000455; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.58E-06 6.91E-02 7.19E-05 8.10E-04 45 192 "C1QTNF3,SEMA6A,AMH,AMPH,BIN1,AMT,APBB2,SLC4A4,BMP7,SYNJ2,CAMK2B,CBFA2T2,RAB28,IQCK,NECTIN3,DMPK,DTNA,ZNF589,DISC1,ADAM28,MSL3,ATXN2L,MMP16,ZNF862,NF1,SLC11A2,PLXNB1,ZFHX4,ASAP3,COA1,TSNAXIP1,DOK5,TROVE2,NXT2,EXOC7,HEY1,CDK20,METTL3,PDIA2,LMF1,REEP1,TFIP11,EMSY,ADAMTS9,SENP7" Drug ctd:C086401 pentabromodiphenyl ether CTD 1.69E-06 7.42E-02 7.70E-05 8.68E-04 198 1270 "ACHE,CLK4,TMEM132B,CCDC85A,TMCC3,ADRB2,BEND6,KLHL13,AGT,KCTD16,C1QTNF1,SPARCL1,SRPX,LCORL,GAS7,TNRC6C,RGS20,PLA2G4C,ZSCAN18,ZBTB10,RASL11B,SLC2A11,ARHGEF7,FUBP1,CACNA1G,RAB29,CA12,CAMK2A,CH25H,CBS,KYAT1,CCNT1,CD86,DGKI,CDH2,DCLK1,CCPG1,TBRG4,CHRNA4,NDST3,CNN3,CNTN1,WHRN,AKAP5,SLC4A8,CRHBP,AKAP12,CRMP1,ABCG1,CRYM,CS,LRRC3B,ERC2,CTH,MYEF2,GRIN3A,DNM1,CPEB2,DOCK2,DPYSL2,DTNA,FEM1B,EEF1D,FSD1L,FAM13A,EGFR,MBNL2,EGR3,EIF4G2,RGS17,ENO2,RCAN2,ABCA8,ZNF585B,TUBA1B,TUBB3,CORO2B,FGF14,ATP5PD,FOXO3,FLNC,DCTN2,UFM1,USP21,TRIM16,SARAF,GAD1,MTHFD2,ZNF559,SRRM4,GATM,GLUL,GPT2,GPD2,STMN2,GUCY1A1,GUCY1B1,HLF,HP,SMAP1,IRF8,IGF1,KIAA1755,IL6R,FAM69A,JAK2,KCNB1,L1CAM,LAMA2,STMN1,LMO2,MAP2,MAPT,MAT2A,AQP11,ADAM22,MX1,NEXMIF,NCF2,NDP,NEFM,ALDH1L2,NPTX1,CLDN11,GPR137C,PCDH8,PDE3A,TMOD2,CYTL1,OLA1,ABCB1,RETREG1,XRN1,PKM,PCDH18,SMIM7,PDZRN4,PSAT1,MAPK3,FITM2,DIRAS2,APTX,PTN,PTPRO,C1orf54,RGS4,ARMH4,RPS6KA2,MEG3,MAPK12,SARS,SBF1,CSRNP3,SCN2B,FNIP1,KIF21A,FERMT1,SHMT2,SLA,RADIL,CCDC88A,CPEB4,SNCA,SPP1,ZBTB43,RBM26,CLSTN2,TTBK2,RGL1,SEPT3,JMJD6,SYP,SYNE1,TEK,DNAH7,C18orf54,THRA,PARD3,KAT6B,TPM1,TUBB2A,UCHL1,ZNF709,BCL2L13,VLDLR,KLC2,GUSBP1,PCDH20,ZNF708,ZNF24,DPYSL5,LAMP5,SLC38A1,TUBA1A,HNRNPA3,RNF170,NHSL1,NETO1" Drug ctd:D005473 Fluoxetine CTD 1.73E-06 7.58E-02 7.87E-05 8.86E-04 67 331 "ADCY8,ADORA1,AMPD2,ARNTL,ARRB1,ARRB2,PDE8B,ATP2A2,CACNA1G,CCK,DCLK1,CNR1,CLOCK,CRY2,EGFR,EGR3,NRN1,PTK2B,TUBB3,PPP1R1B,FGF1,BAIAP2,GAD1,GCK,GPD1,GRIA2,IL12A,ITGAM,ITPKA,KCNH2,KCNJ5,L1CAM,LSS,SMAD1,MBD1,NF1,NPY,NPTX2,NTRK2,OXTR,PDE4A,PDE4B,PDE4D,SERPINI1,PLCL1,PLEC,PLXNB1,MAPK3,RELN,RGS3,ROBO2,S100B,SGK1,CNKSR2,DDN,STXBP1,PLCB1,SYN1,ARC,SYP,ICAM5,TPM1,VGF,VLDLR,XPO1,SLC30A3,SLC17A7" Drug 2378_UP Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.82E-06 7.99E-02 7.88E-05 8.88E-04 43 181 "BRAP,BIN1,GAS7,ARRB2,ST3GAL5,CACNA1I,CD86,CD38,KCNAB3,RCBTB2,CHN2,TPP1,CREM,PPP1R16B,SEC14L5,DOCK4,HEYL,PIPOX,DLC1,GNAO1,GRIK5,TAGLN3,ZNF862,NEK1,PDE4B,ENPP2,PLEC,PILRA,PTPRB,GAL3ST4,SEC14L1,SH3BP2,LIMS2,ARHGEF40,ZSWIM8,ARHGEF9,PLCB1,PDLIM2,TBCEL,ZNF34,TK2,TRPS1,FLRT2" Drug 5743_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.82E-06 7.99E-02 7.88E-05 8.88E-04 43 181 "LHX2,SNPH,HDAC4,RASSF2,KLHL3,TMCC2,ABCC5,EIF5,TNK2,ETV1,TBC1D16,ST3GAL6,FAM49B,CGREF1,SESN1,GUCY1A1,ITPKB,MARK3,SCAMP5,PDCD2,PDE4A,KCTD15,MBOAT7,MINDY2,MAPK7,SH3TC2,GTDC1,RGS3,CCDC25,FAM102A,ST6GAL1,FAM214B,PDZD2,CDK19,DIP2A,TBL1X,TRIM2,GPR161,NACC2,HEY1,HIRA,FZD3,MARCH8" Drug 3688_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.82E-06 7.99E-02 7.88E-05 8.88E-04 43 181 "NME5,CDC14B,ARNTL,ADGRB2,ST3GAL5,HIP1R,USP2,RAB26,ABCG1,PDE4DIP,CNTNAP2,CTH,C2CD2L,DTNB,AASS,RGS17,TAOK3,BAIAP2,FYN,STON1,TPPP,GSN,GUCY1B1,FAM69A,ITGA7,KCNH2,LIFR,MMP16,TAGLN3,PCDH9,SERPINI1,RETREG1,RGS4,STUM,SH3GL3,NFASC,ELOVL4,RGL1,SYT1,OBSL1,TNS1,TRIM9,SLC17A7" Drug 3702_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASIC1,ATP2A2,BMP7,CACNA1I,LDLRAD4,CD86,DCLK1,MAGI1,CHN2,STOML1,HAPLN1,AATK,CSF1R,PDE4DIP,CYBB,DTNA,MTSS1L,ZNF391,FGFR1,AGAP2,CSDC2,SPACA9,SOX21,NXPH3,ATXN2L,HLF,INPP5B,ITGA7,LYRM9,NTRK3,PLXNB1,PDZRN4,VPS13C,PTCH1,RGS12,ZFP2,STUM,SLA,CXXC4,PLCB1,ARC,MCF2L,OBSL1,TNS1,TPM1,EPM2A" Drug 3570_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "SPARCL1,LTBP4,CDC42BPA,APC,EPB41L5,CHRD,CFLAR,SYNJ1,SYNJ2,CFAP410,SLC16A4,QKI,COL9A3,NECTIN3,CNTNAP2,DCAF4,CYBB,C3orf18,STX2,GALC,SPACA9,GSTM5,VSIG4,INPP5B,KCNN1,MAP2,MAPT,ADAM22,NF1,P2RY1,MINDY2,PRODH,RELN,RGS12,ZNF821,PREX2,ARHGEF40,COA1,LIMCH1,TSNAXIP1,SYT5,DMXL2,SLC44A1,WIPF1,SLC30A3,GDPD5" Drug 1541_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "RALGAPA1,ASIC1,AK2,APBB2,APOC1,PPP4R4,STX16,RGS9,SCAPER,CACNA1I,BAIAP3,CALB1,CDH2,CLGN,TAOK2,CSF1R,ZNF804A,DTNA,EIF4G2,STX2,FHL1,FLNC,TXNL4A,TDRKH,SPACA9,HLF,ICA1,KCNH2,KCNJ5,MAPT,MID1,NF1,PFKFB2,PPP2R2B,PRPH,PTN,CEP97,SCN8A,SYBU,KDM4D,KDM4C,ERC1,SAMSN1,GDPD5,KAT6A,TIGD6" Drug 2760_DN Riboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "AP2A2,APBB2,APOC1,PPFIA3,MARCH3,BMP7,CA12,KYAT1,CNOT8,PDE4DIP,TBC1D5,KIAA0586,MFAP3L,DTNA,MBNL2,MRNIP,VPS13B,FGFR1,B4GALNT1,GNG4,CACFD1,INPP5B,KCNH2,KPNA5,MAPT,MPP2,NEK1,MBOAT7,CEP97,GTDC1,RNASEL,SLC22A4,SMARCD3,SOX3,UNC5B,NXT2,STX1A,PLCB1,ASTN2,PCDHA6,ZNF34,CLDND1,KCNK12,FTSJ1,PHTF2,SENP7" Drug 5857_UP Isoconazole [27523-40-6]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "RALGAPA1,MTUS1,TRMT9B,ARRB2,NRP2,MYRF,CFAP410,ASIC3,NRXN3,CSF1R,CSNK1E,PDE4DIP,ARHGEF4,EDN3,MBNL2,AASS,ELN,FCGRT,DCTN2,FYB1,DENND2A,ERAP1,TMEM8B,ELOVL5,TJAP1,SCIN,MAPT,MT1M,PPP2R2B,MAPK10,ZSCAN32,FBXW7,SBF1,FRMPD1,ABLIM3,FAM214B,ELMO2,KDM4B,ARHGAP26,PLCB1,ARC,DICER1,TK2,TNS1,WIPF1,LAT2" Drug 4637_DN Perphenazine [58-39-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "C1QTNF1,TRMT9B,AMH,SEMA4G,PDE8B,ATP2B2,ADGRB2,CFAP410,CAMK2G,TAOK2,ABCG2,IQCK,CABP1,TBC1D5,DTNB,FAM13A,ING4,SPEG,AFF2,DENND2A,GLYR1,HTATSF1,LPAR4,HNMT,ICA1,LIG4,MX1,NPR2,GRAMD1C,CNTLN,PTN,PTPRB,ZSCAN2,FRMPD1,ASAP3,RBM34,SPTAN1,SS18,ADGRL3,CRTC1,TMPO,RIMBP2,CABIN1,TNS1,MPPE1,FAM13C" Drug 3813_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADRA1D,AMPD3,CDC42BPA,GAS7,APOC1,ALDH7A1,MYRF,IL33,CFAP410,LARGE1,TPP1,HOMER3,CNTNAP2,MFAP3L,DTNA,HIPK3,ETV1,SCML2,FGF1,FYB1,GRIK5,MUM1,ATXN2L,ICA1,TJAP1,KCNB1,MAP2,MARK1,ADAM22,TAGLN3,OPRL1,PDE4A,MINDY2,PRKAR1B,RPS6KA2,ZFP30,PREX2,ZNF334,BTBD7,SNCA,SMG6,CHST8,AP4E1,FLRT2,LMF1,KCNAB1" Drug 3883_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADRA1D,SEMA6A,ALCAM,CHRD,KSR1,CACNA1I,CAMK2B,CAPN3,CDO1,SNCAIP,FAM169A,MFAP3L,C3orf18,RASGRP2,CAMKK2,HPGDS,GLYR1,POLL,PRUNE2,TDRKH,KCNJ5,L1CAM,MAPT,MATN3,MEF2C,KITLG,NNAT,LRP12,NECAB2,MINDY2,PTPRH,ENOX1,ZDHHC14,RFX3,RGS12,KCNIP1,SH3GL3,ZSWIM8,PEG10,TROVE2,CRTC1,SLC35G2,TPM2,TRPM2,ZNF711,JPH3" Drug 6660_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASPHD1,LGR5,CDK10,ATP6V0A1,ADGRB2,CFLAR,BMP7,MTMR3,CACNA2D2,STOML1,SULT4A1,PDE4DIP,C2CD2L,DTNB,EPHB1,ZNF549,ETV1,REEP2,OLFM1,FGFR1,PRELID3A,NSG1,OGA,CSDC2,GRIK5,GSN,SHISAL1,ITGA7,KIT,CLDN11,PDE4B,POU6F1,MAPK10,ZSCAN32,PTPRO,TCP11L1,DZIP1,SLA,SLC12A4,PCDHGB6,TPM2,UGT8,LAT2,KCNK12,ZNF225,PRDM10" Drug 4213_UP Austricine [10180-88-8]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "FAM135A,BIN1,APC,CDK13,ATP1A3,N4BP2L1,KSR1,SCAPER,CACNA1A,HAP1,LDB2,SCARB1,RAB33A,HOMER3,FAM149A,NCOR2,ABCG1,SPEG,FLT1,PDLIM5,SYT17,ADAM28,USP19,STON1,PTPRT,ATXN2L,IRF8,MARK1,MMP16,MSI1,CNOT4,OPRL1,PFKFB2,MTRF1L,PRPH,PTPRH,RASGRF1,PBRM1,CARF,PNMA8A,PKNOX2,SNCA,SMG6,TNS1,LAT2,MKRN3" Drug 4256_UP Tocainide hydrochloride; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "NDRG2,ADORA1,NME5,LTBP4,SEMA7A,PKP4,APAF1,GAS7,PPP4R4,N4BP2L1,ATP6V0A1,NRP2,MTMR3,NCOR2,SUSD5,CNTNAP2,MAML1,EXOG,EDNRA,IRAK4,SRPK3,NCALD,IGSF6,ZNF391,FGFR1,AGAP2,GATM,TDRKH,GRIK5,ELOVL5,LSS,MAN2A2,NPTX1,DCHS2,PTPRN2,ZMAT4,RET,SALL1,SYP,ASTN2,ADGRL3,SMG6,AP4E1,TPM1,ZNF24,DPF3" Drug 5635_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ACTN1,AMPD3,APAF1,MARK4,NRP2,KSR1,ARHGEF1,CACNA2D2,ASIC3,RAB33A,CNTFR,WHRN,CPS1,CRMP1,CNTNAP2,DTNA,DTNB,TOM1,EGR3,ZNF589,FHL1,HPCAL4,PCLO,TJAP1,MEF2C,NPTX2,CDK18,PFKFB2,SERPINI1,PLCD1,CNTLN,ZSCAN2,CCDC40,C1orf54,ZFHX4,SEMA6D,FAM214B,LIMCH1,HECW1,KIAA1107,WSCD1,DICER1,UBE3A,FLRT2,LAT2,KCNAB1" Drug 7230_UP Convolamine hydrochloride [500-56-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "FZD9,AK2,APBA2,APC,APLP1,CA12,CLGN,SOCS6,FAM189A2,AKAP6,BAG4,CSF1R,GREB1,GIT2,DTNA,CNNM1,ERCC2,REEP2,DLC1,BAIAP2,AGAP2,GLYR1,TDRKH,SPACA9,GRM8,GSN,ATXN2L,IL6ST,MAN2A2,MBD1,KITLG,MITF,MSI1,MYT1,LRP12,PRPH,GTDC1,FUZ,DOK5,TTBK2,SYT5,WSCD1,ZKSCAN5,SLC30A3,MAP3K12,HPS4" Drug 4635_DN Androsterone [53-41-8]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "TRMT9B,AMH,APC,PDE8B,ATP1A3,ADGRB2,BAIAP3,PLEKHB1,LHX2,RAB26,AKAP7,CABP1,CSF1R,ARHGEF4,SGSM2,DTNB,HEYL,AASS,ING4,MTSS1L,NRN1,FGFR3,AFF2,CINP,FYN,ZNF44,SIGLEC8,GLYR1,CACFD1,SOX21,ICA1,KCNF1,MARK3,MYT1,CNOT4,PALM,KLHDC8A,SCN8A,ZNF821,SH3BP2,FRMPD1,CHST8,THRA,TIAM1,UGT8,NT5M" Drug 6746_UP Calciferol [50-14-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASPHD1,SYN3,AGT,NME5,LTBP4,ALK,DOC2A,GAS7,DDO,APOC1,CDK13,ADGRB2,CALB2,LARGE1,DLGAP1,TPP1,CRMP1,HAPLN1,MFAP3L,PLPPR4,DTNA,DUSP9,ING4,NCALD,F5,ERAP1,GNAL,IL12A,LSAMP,MYCN,P2RY13,NEFM,P2RY1,TREM2,TMEM231,C1orf54,ENOX1,RASA3,FAIM2,ZHX3,SPP1,IQSEC2,CEP68,TMEM121,TLR4,SLC17A7" Drug 4209_DN Zardaverine [101975-10-4]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASPHD1,C1QTNF1,AMT,CDC42BPA,SEMA7A,KYAT1,SH2B1,AATK,VCAN,RIMS2,DCAF4,C2CD2L,SLC12A6,DTNA,CNNM1,ZNF391,FGF1,GCNT2,GNG4,INPP5B,KIFC3,PACRG,MGAT3,ENPP2,PIK3R1,CNNM2,BCAS3,PTPRH,RAD51D,SH3TC2,FAM184A,GSTCD,FBXW7,CSRNP3,ATXN7,NLGN1,ANKRD6,EXOC7,TMEM121,ZNF34,RUNDC3B,NDRG4,ZNF225,NAV3,KCNAB1,MPPE1" Drug 5927_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASIC1,ADRA1D,CDC42BPA,APAF1,PLA2G4C,KALRN,PLAA,TPP1,ARHGEF6,AKAP7,SPOCK2,MFAP3L,RUSC2,DTNA,FGF13,SCARA3,GAD1,GPD1,SPACA9,AP4S1,ITGA7,MAP4,AFDN,NEK1,NNAT,PDE4D,PLEC,PTPRH,RNASEL,FBXW7,EMID1,DGLUCY,ZNF821,FNDC3A,SLC2A5,FAM214B,PKNOX2,ZSWIM8,TROVE2,ARC,EXOC7,DNAH7,AP4E1,THRA,TRIO,SLC30A3" Drug 6291_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASIC1,APBB2,PPFIA3,ADAM23,NRP2,SCAPER,CALB2,KALRN,RUNX1T1,ARHGEF2,TAOK2,LHX2,SLITRK5,EDIL3,EDNRB,PLXNC1,MRNIP,COQ7,EZH1,TRAF3IP2,DENND2A,ZNF276,GRIK5,IL6ST,KIFC3,KPNA5,MT1M,STRN3,SNRK,PTPRE,ENOX1,NEK11,SEMA6D,ZFP30,SH3BP2,PEX26,CCDC88A,SLC9A5,KIF13A,DOK5,CEP68,PHLDB1,KIAA1107,TRIO,NT5M,NAV3" Drug 5337_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "AK2,ALCAM,APC,APLP1,MARK4,CACNA1I,C5,KYAT1,CNTN1,AKAP7,HDAC4,MAML1,GIT2,DNM1,ING4,F5,ZNF589,CAMKK2,OGA,BTN2A1,HNMT,MAP4,MAPT,MITF,MPP2,NEK1,NF1,NPR2,NLE1,SAMD9,TMEM104,RIPOR1,RGS3,RGS12,CCDC25,BTBD7,SMARCC2,KDM4B,ZBTB43,CAMTA2,EXOC7,TRIM2,PCDHGB6,ZNF34,TK2,XRCC4" Drug 3481_DN Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "NDRG3,ADRA1D,APBB2,APOC1,CDK10,SCAPER,CFAP410,CAMK2G,PLEKHB1,TAOK2,TPP1,VAX2,CRY2,CSNK1E,CTH,TOM1,EZH1,ZNF589,FECH,FAM49B,DISC1,GCNT2,LPAR4,ICA1,IPO5,MATK,MIA2,MPP2,NF1,MBOAT7,PRPH,TMEM104,PTPRE,ZNF821,FBXO11,ANKRD6,LIMCH1,FNBP1,CLASP2,TIAM1,TPM1,VGF,KCNK12,ZNF45,ST7,PHTF2" Drug 6765_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ABHD6,AP2A2,BIN1,EPB41L5,ARRB1,ALDH7A1,CAMK2G,SCARB1,CACNA2D2,SLIT2,PICK1,CPS1,ARHGEF10,PDE4DIP,ARHGEF4,RCAN1,NCALD,SCML2,SEMA4D,DISC1,SEPT9,GSN,ATXN2L,ELOVL5,KCNH2,MAP4,NNAT,SLC11A2,RETREG1,PPP2R2B,FAM184A,ZNF821,COA1,LIMCH1,RBM34,ARHGAP26,SPTAN1,SPART,PHLDB1,PLCB1,EXOC7,SLC44A1,HIRA,EMSY,HPS4,RNF170" Drug 6950_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ABHD6,FAM131A,SCAPER,CA12,MAP4K4,ARMC8,CRY2,NCOR1,ABCG1,PPP6R2,ZNF337,DBT,MFAP3L,KIAA0753,C2CD2L,LYPD1,IRAK4,MTSS1L,INPP5K,KCNMB4,GRB10,ATXN2L,KCNF1,OXTR,ZSCAN32,ZCWPW1,GTDC1,RPS6KA2,GALNT10,FERMT1,ABLIM3,EPN2,SMARCC2,KDM4B,ELOVL4,NSFL1C,ARHGEF9,ASTN2,TBL1X,KAT6B,SSBP2,HIRA,VGF,LMF1,MAP3K12,GAN" Drug 2754_DN Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "AK2,APC,CDK10,ATP6V0A1,ADAM15,GYG2,PLAA,FAM189A2,MAP4K4,PDE4DIP,DZIP3,C2CD2L,RCAN1,TSPAN5,SUGP2,TNK2,MRNIP,ENO2,EZH1,KAT8,FGFR1,SRCAP,PACSIN2,ITPKB,LIG4,KITLG,MKLN1,CNOT4,SLC11A2,PCDH9,CCSER2,ZSCAN32,ZCWPW1,GTDC1,GSTCD,PEX26,SLC22A4,ZSWIM8,CLASP2,ASTN2,TACC1,PCDHA6,AP4E1,HPS4,SMIM8,RNF170" Drug 4316_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "CDK10,ARNTL,SLC4A4,FOXN3,CNOT8,TAOK2,HOMER3,VCAN,PDE4DIP,MFAP3L,EDIL3,ING4,VPS26C,FGF1,PDLIM5,FAM49B,OGA,HTATSF1,POLL,GNG4,IL6ST,LRP12,WDR25,PTN,C1orf54,TCP11L1,FBXO11,PPP4R3A,DOP1A,SPTB,SYT1,SMG6,ZEB1,CHST8,TRIO,RPRM,VIPR2,ZNF711,ZNF74,TFIP11,ZNF225,EMSY,EVI5,VPS35L,KCNAB1,PHTF2" Drug 3349_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASIC1,NDRG3,ALCAM,KCNAB2,PDE8B,MARK4,SCAPER,CA4,HAP1,ARHGEF1,CACNA2D2,AKAP7,WHRN,CSF1,ARHGEF10,DOCK4,PARD6A,EXOG,EGFR,CDKL3,HNMT,ICA1,MID1,MMP16,ADAM22,MYO7A,NPTX1,SLC11A2,MAPK7,PRODH,CNNM2,PTN,GTDC1,FERMT1,IQSEC2,ZBTB43,ELOVL4,STX1A,CHST8,TNS1,ZKSCAN5,VLDLR,WIPF1,KCNK12,XRCC4,MPPE1" Drug 6690_UP Flucytosine [2022-85-7]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASPHD1,APAF1,SLC4A4,RGS9,NRP2,KSR1,SCAPER,GYG2,LDLRAD4,KALRN,MAGI1,CHN2,AKAP5,CSF1R,IPCEF1,VCAN,DAPK3,MFAP3L,C2CD2L,HIPK3,SEMA3D,MBNL2,RASGRP2,ST3GAL6,ZNF589,PDLIM5,SIGLEC8,DISC1,CACFD1,GRM8,ATXN2L,ICA1,KCNJ5,NPY,GPR85,PRKCB,ZSCAN32,RNASE1,TCP11L1,PKNOX2,SOX3,IZUMO4,ARHGEF9,PCDHA5,AP4E1,FAM13C" Drug 4065_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "MTUS1,NME5,CDK10,ZSCAN18,ADAM15,ADGRB2,BCHE,SCAPER,CACNA2D1,KALRN,HAPLN1,NCOR2,CSF1,CSF1R,PHF14,C2CD2L,EDIL3,ZNF391,ETV1,PDLIM5,PRELID3A,DISC1,NEU3,GPER1,CACFD1,IL6R,MSR1,PLCD1,CNNM2,ELOVL2,PTN,RGS4,KCNIP1,ASAP3,FBXO11,SLC14A1,KDM4B,IZUMO4,CDK19,RBM26,SS18,PHLDB1,SYT5,TNS1,ZNF225,KCNAB1" Drug 6228_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADRA1D,SEMA6A,BIN1,APOC1,BCAS1,PPFIA3,PLA2G4C,TPP1,CNTFR,IQCK,PDE4DIP,DAPK3,TMCC2,GLYR1,TJAP1,INPP5B,KHK,KIF2A,MATK,KITLG,MSI1,MSR1,NOVA2,NPR2,PPP5C,SAMD9,WDR25,ELOVL2,FAM184A,KHDRBS2,RGS12,ZFP30,ASAP3,SLC11A1,IZUMO4,HECW1,DBNDD2,ZBTB43,THSD1,PHLDB1,EXOC7,ZNF34,TRPM2,UBTF,SEMA3B,MPPE1" Drug 7331_DN Naftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ABR,AP2A2,APC,ATP6V0A1,MTMR2,LRRFIP1,SMARCAL1,ZFYVE16,GIT2,DBN1,LYPD1,DNM1,CELSR3,ENO2,FAM49B,GLUL,KCNH2,LSS,MAP4,MATK,NF1,NFYA,NPR2,RETREG1,CNNM2,TMEM231,RNASEL,GSTCD,NEK11,SUPT20H,PPP4R3A,ZKSCAN3,SMARCC2,PDZRN3,POGZ,THSD1,ELOVL4,IQCE,TMEM121,ZBTB14,REEP1,FTSJ1,UPF3A,MAP3K12,MPPE1,EPM2A" Drug 4633_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "TRMT9B,MADD,PDE8B,KIF1A,BAIAP3,LDLRAD4,SYNGR3,LARGE1,CABP1,COL9A3,SLC4A8,CNTNAP2,MFAP3L,SPOCK3,SGSM2,CHRDL1,DMPK,CELSR3,PHF20L1,MRNIP,STX2,EZH1,NRN1,SCARA3,ANKFY1,FAM49B,GFER,MSL3,HNMT,SCIN,KIF2A,MEF2C,NNAT,PCDH9,GRAMD1C,PTN,ZSCAN2,TMEM231,ZFP30,ASAP3,AMBRA1,LIMS2,EXOC7,TPM2,MAP3K12,EPM2A" Drug 2550_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "APC,MARK4,SCAPER,CACNA1A,CBFA2T2,SOCS6,EPS15L1,TPP1,CREM,DCAF8,TM9SF4,KIAA0753,RHOBTB1,MRNIP,STX2,ST3GAL6,FECH,LILRA2,ATXN2L,KIF2A,MEF2C,MIA2,LRP12,PPP3CC,PTPRO,MAPK12,SEC14L1,SH3BP2,DZIP1,ANKRD6,KBTBD4,ZBTB43,TSPYL2,THSD1,TACC1,SLC44A1,TPM1,CDK20,SMUG1,SSBP2,PLPPR2,LMF1,ZNF24,ZNF74,EMSY,SMIM8" Drug 4973_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ASIC1,ABHD6,APLP1,FAM131A,NRP2,GYG2,CACNA1I,BAIAP3,LDLRAD4,CLGN,SOCS6,LHX2,CNTFR,CRY2,CSF1R,VCAN,RASSF2,EDIL3,FCF1,LRRC17,IGSF6,PTK2B,ZNF589,SCARA3,FOXF2,FYB1,RUNDC3A,STON1,GPER1,PCLO,GSN,ICA1,TJAP1,KCNH2,KCNJ5,KPNA5,MAP2,ENPP2,PLXNB1,PDZRN4,TCP11L1,PKNOX2,SNCA,DOP1A,AP4E1,PIK3R5" Drug 6410_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "GAS7,PPP4R4,CACNA1I,ARHGEF1,CRY2,TBC1D5,ARMCX2,B3GAT3,RUSC2,CHRDL1,DMPK,FGFR1,DLL3,TRAF3IP2,MSL3,PRRC2B,TDRKH,HSF2,ICA1,MEF2C,MIA2,NPR2,PLCD1,PLXNB1,PRKAR1B,PTCH1,TMEM231,ZCWPW1,NEK11,RXRA,SBF1,SCN8A,BTBD7,IFT122,CEP68,SYN2,COBL,ASTN2,DMXL2,SZT2,TNS2,TK2,ZNF74,HPS4,KCNAB1,SENP7" Drug 7210_UP Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "NME5,AMT,APBB2,APLP1,ARRB1,MARK4,ATP2A2,ATP2B2,KSR1,SCAPER,CA4,CALB1,CALB2,CAMK2G,SLC16A4,PCYT1B,ARHGEF10,DUSP9,PHF20L1,ERCC2,F5,DLC1,FHL1,GALC,GCNT2,GLYR1,BTN2A1,RNFT2,ELOVL5,KCNF1,GIT1,ZNF862,NEK1,PDE1C,LRP12,PPP2R2B,ZSCAN32,ZSCAN2,KHDRBS2,ZFP30,FRMPD1,SNCA,TTBK2,DOCK9,RIMBP2,ITM2C" Drug 2379_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "CDC42BPA,ARRB2,PDE8B,C5,CACNA2D1,USP2,SLC16A4,SLIT2,RCHY1,PDE4DIP,DZIP3,PPP1R16B,SPOCK2,DTNA,SEZ6L2,CELSR3,MRNIP,DLC1,FGF12,IQCG,GCNT2,ADAM28,RUNDC3A,FERMT2,ATXN2L,MEF2C,TAGLN3,NF1,CCSER2,MINDY2,ABLIM3,PEX26,EPN2,LIMS2,FAM214B,SLC11A1,SNCA,TMCC1,ZSWIM8,KDM4C,PLCB1,ASTN2,TBCEL,WSCD1,CRTC1,SSBP2" Drug 3841_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "SYT13,PLA2G4C,MYRF,LDLRAD4,CACNA1A,CDO1,CLTB,CNR1,CNTN1,RASSF2,RUSC2,DRP2,EDN1,AASS,ING4,MTSS1L,PTK2B,DLC1,OLFM1,DISC1,GPER1,GSTM5,IRF8,KCNJ5,KHK,LSS,MEF2C,MMP17,MSR1,PDZRN4,POU6F1,PRKAR1B,ZFHX4,ASAP3,KIF13A,KDM4B,ZNF423,SPTB,JMJD6,TBCEL,DOCK9,CRTC1,THRA,FLRT2,SLC30A3,ITM2C" Drug 6669_UP Benzbromarone [3562-84-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "RALGAPA1,ADORA1,CDK13,PTCH2,RASL11B,SLC2A11,CALB2,CBS,CCK,SCARB1,LARGE1,TAOK2,EPS15L1,NRXN3,ENTPD4,ABCG1,CNTNAP2,DAPK3,SPOCK2,MFAP3L,EDN1,EDN3,HEYL,APC2,RACK1,FLT1,OGA,TPPP,GSN,KIT,MGAT3,ADAM22,PFKFB4,FXYD1,PRPH,PTH1R,ZSCAN2,ZNF334,HECW1,ZC3H13,PCDHGB6,CRTC1,SLC17A7,KCNAB1,DPF3,JPH3" Drug 5794_UP Methazolamide [554-57-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "PPP4R4,ATP6V0A1,KIF1A,BMP7,HAP1,USP2,SCARB1,FOXN3,TPP1,PICK1,WHRN,AKAP5,RIMS2,PYGO1,HIPK3,PLXNC1,ING4,EZH1,CORO2B,KAT8,FLT1,SYT17,NEU3,PRUNE2,GRIK5,KCNQ3,AFF1,ADAM22,P2RX7,PTPRB,PID1,ACSS3,CCDC40,RPS6KA2,EMID1,ZNF821,SLA,SNCA,KDM4B,ZSWIM8,ZBTB43,TACR1,VAV1,REEP1,ADAMTS9,KCNAB1" Drug 6686_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADGRF5,DOC2A,ANK2,BCAS1,BMPR1B,CACNA1I,LDLRAD4,KALRN,HIP1R,SLC16A4,DLGAP1,CACNA2D2,TAOK2,NRXN3,HAPLN1,NCOR2,ARHGEF10,MYEF2,EDN1,HEYL,ZNF549,GABRA3,ALDH1L1,HPGDS,GPR75,TOX3,LPAR4,GRM8,SOX21,ATXN2L,ITPKA,KITLG,P2RY13,NNAT,NOVA1,NTRK3,NECAB2,EMID1,ZFP30,ST6GAL1,CNKSR2,SLC9A5,COBL,KCNK12,REEP1,KCNAB1" Drug 4400_UP Prednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "SEMA4G,AZGP1,GYG2,BAIAP3,RUNX1T1,SEPT7,KCNAB3,ASIC3,CNTNAP2,DCAF4,SPOCK3,EDN1,FRY,FAM13A,LRRC17,OLFM1,FGFR1,NEU3,STON1,GSTM5,SOX21,LAMA2,MID1,ADAM22,MX1,NNAT,NPR2,PDE1C,PLCD1,PNMA3,LRRN3,CEP41,GDPD2,CRTAC1,RPS6KA2,ZFP2,STUM,CPEB3,SNAP25,HECW1,ARHGAP26,CDK19,TNS1,CA14,ITM2C,GJC2" Drug 3632_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "BEGAIN,PDE8B,SLC4A4,ALDH7A1,ARHGEF7,SGCE,LDLRAD4,CA4,HAP1,SLC16A4,CLGN,LHX2,VAX2,AKAP5,PDE4DIP,MFAP3L,C2CD2L,ING4,ZNF589,FGF13,FOXF2,SEMA4D,TDRKH,PCLO,RASSF8,MAPT,MATK,MPP2,NEK1,NPTX1,NPTX2,PFKFB2,SMOX,PPP5C,TMEM104,RGS12,KCTD17,GSTCD,SH3BP2,TSNAXIP1,SPTB,KIAA1107,RPGRIP1L,SLC35G2,WIPF1,UBE3B" Drug 6324_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADCY6,APAF1,EPB41L5,PPP4R4,PDE8B,DNAH17,MARK4,BMP7,BAIAP3,USP2,ABCG2,CREM,NCOR2,AATK,ARHGAP24,DAPK3,MFAP3L,EXOG,CDON,IRAK4,FAM198B,FGF1,SCARA3,ERAP1,ZNF276,GLYR1,LPAR4,IRAK3,KCNJ5,KHK,LIG4,SMAD1,NECAB2,POLG,MAPK7,MASP1,WDR25,ZSCAN32,GAL3ST4,NLGN1,SLA,ELMO2,PHLDB1,ASTN2,ADGRL3,LMF1" Drug 6188_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.00E-02 7.88E-05 8.88E-04 46 199 "ADORA1,APBB2,PPFIA3,CDK10,BMP7,CACNB4,LARGE1,CNR1,CSF1,ARHGAP24,DAPK3,SPOCK2,CDON,DPP6,DTNB,HIPK3,VPS13B,RASGRP2,TLR7,SEPT9,HNMT,KCNJ5,KHK,MMP17,ADAM22,NF1,NTRK2,PFKFB2,RETREG1,CNTLN,NKAIN1,RGS4,RGS12,PNMA8A,ZNF821,SH3BGR,SH3BP2,FNDC3A,SLC11A1,ARHGAP26,SS18,RPRM,VGF,ZNF24,ST7,PHTF2" Drug 2344_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 44 187 "GAS7,SEMA4G,MARK4,ST3GAL5,CACNB4,CAMK2G,CD86,CD38,RCBTB2,CHN2,SEC31B,CREM,ENTPD4,SIPA1L1,PPP1R16B,DOCK4,MFAP3L,TOM1,CELSR3,HSD17B14,COQ7,ST3GAL6,BAIAP2,PDLIM5,INPP5K,LILRA2,SLC2A6,TJAP1,MYCN,ZNF862,TREM2,CCSER2,PTPRE,BEND5,TCP11L1,FAM102A,ZKSCAN3,ZSWIM8,ARHGEF9,WSCD1,TK2,SMUG1,TST,EMSY" Drug 3893_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 44 187 "ADRA1D,BIN1,ANK2,KCNAB2,PLA2G4C,ATP1A3,ATP2B2,CACNA1I,CFAP410,CBARP,CNTN1,MYRIP,PDE4DIP,CDON,RCAN1,EDNRA,DLC1,FGF1,FGFR1,FYN,GFER,KCNH2,KCNJ5,MEF2C,MIA2,ADAM22,SERPINI1,PLCB2,GRAMD1C,RELN,ZDHHC14,CRTAC1,CARF,KCNIP1,CLIP1,SATB1,STUM,CPEB3,ARHGEF40,IZUMO4,ZC3H13,ARC,TNS1,LAT2" Drug 2856_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 44 187 "RALGAPA1,APBA2,CFLAR,CACNA1I,LDLRAD4,CA12,KYAT1,ARHGEF6,GREB1,SPOCK2,DBT,TSPAN5,EGR3,ANKMY1,FAM49B,INPP1,INPP5B,JAK2,KCNF1,KCNH2,LMO2,MAN2A2,MID1,AFDN,NF1,GPR85,C19orf57,ELOVL2,C1orf54,RET,RGS12,EMID1,SGK1,SH3BP2,SYBU,PEX26,COA1,SNCA,SOX3,DMXL2,ZKSCAN5,REEP1,ITM2C,TIGD6" Drug 6868_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "ALCAM,BEGAIN,AMH,RGS11,BCL7A,CACNA1I,CA4,CACNA2D2,CHRNA4,RAB28,STOML1,WHRN,CRY2,CSF1R,VCAN,SLC12A6,EGFR,RASGRP2,AGAP2,SEMA4D,PDLIM5,USP19,SPACA9,ADAMTS13,GUCY1B1,MITF,NF1,PALM,ZSCAN32,C1orf54,ZDHHC14,RNASEL,RPS6KA2,SLC22A4,SNCA,KDM4B,IQSEC2,TSPYL2,VPS13A,TCF4,PCDHA6,R3HDM1,ZKSCAN5,KCNK12,SEMA3B" Drug 974_DN ikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "ABHD6,DOC2A,APC,ATP6V0A1,EPS15L1,STOML1,HOMER3,ARHGEF6,AKAP7,COL4A5,ENTPD4,AKAP12,MFAP3L,FBXL5,MAMLD1,HIPK3,EIF5,PDLIM5,CGREF1,COPS8,RAB30,HSF2,INPP5B,JAK2,KIF2A,MPP2,ADAM22,LYRM9,CNOT4,SLC25A23,STRN3,TMEM104,RAD51D,MAP6D1,ABLIM3,ZHX3,TSPYL2,TROVE2,NXT2,PLCB1,AP4E1,PLPPR2,XRCC4,MAP3K12,PHTF2" Drug 3708_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "NDRG2,ADD2,BEGAIN,AMPH,PPFIA4,SLC4A4,SLC2A11,NRP2,CA8,CLDN10,TPP1,CNTFR,CSF1,ERC2,EDNRA,FCF1,EGFR,TNK2,F5,DLC1,GFER,GLI2,GSTM5,PADI2,MMP16,ADAM22,NF1,NTRK3,PALM,PDE4D,MAPK10,STK32B,KCNIP1,DZIP1,PEX26,SNCA,ARC,TACR1,ADGRL3,CRTC1,UCHL1,OSBP2,VSNL1,LAT2,RNF146" Drug 3804_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "RALGAPA1,ADGRF5,APBB2,SEMA4G,CBS,ARHGEF2,CACNA2D2,AKAP5,CSF1,RIMS2,TBC1D5,EXOG,HIPK3,OPTN,SCML2,GCNT2,ELOVL5,SCIN,ITPKA,MAPT,MITF,MN1,CNOT4,GRAMD1C,PTN,RPS20,ZNF821,FBXO11,ANKRD6,PREX2,ZNF415,TSNAXIP1,LHPP,POGZ,SS18,ELOVL4,ARC,ASTN2,TMPO,LAT2,KLC2,XRCC4,ZNF24,REEP1,PHTF2" Drug 7341_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "NDRG3,ADORA2A,FAM131A,BAIAP3,KALRN,ASIC3,CLTB,CSF1,CSF1R,PDE4DIP,TBC1D5,GIT2,MBNL2,ING4,EZH1,ZNF589,PRELID3A,GAD1,ERAP1,MALT1,RAB30,STON1,GRB10,RASSF8,HSF2,TJAP1,MEIS2,CNOT4,PDE1C,PLXNB1,ZSCAN2,RGS3,SAFB,ZNF821,FUZ,CNKSR2,SLC22A4,ERC1,SPTAN1,CDK19,PLCB1,WSCD1,ZNF34,ZNF24,EPM2A" Drug 6846_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "NME5,GAS7,SLC4A4,ATP6V0A1,SYNJ1,SCAPER,USP2,ARHGEF1,PLAA,PICK1,FAM149A,AKAP6,CPS1,PDE4DIP,SPOCK3,CDON,EDN1,FRY,MBNL2,ACSL4,ZNF589,PDLIM5,RUNDC3A,GLYR1,RAB30,GPER1,HNMT,ICA1,PDE4A,SAMD9,TCP11L1,SCN2B,ASAP3,FNDC3A,SLC14A1,KDM4B,PDZD2,SPART,SYN2,TRIM2,TNS2,UCHL1,VIPR2,KCNK12,SENP7" Drug 1363_DN Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Down 1.83E-06 8.04E-02 7.88E-05 8.88E-04 45 193 "ASIC1,ADD2,AK2,OGT,CDC42BPA,STX16,N4BP2L1,ADAM15,CFLAR,LRRFIP1,SRSF11,TAOK2,CLCN3,DAPK1,PHF20L1,SUGP2,APH1A,KCTD3,IRAK4,RASGRP2,SEMA4D,TRMO,FAM49B,ZNF44,HTATSF1,CACFD1,AFF1,NEFH,NF1,PDE4A,MAPK10,AMBRA1,SLC11A1,UNC5B,CAMTA2,KANK1,TAF6,PDLIM2,DICER1,TK2,KAT6B,TNS1,WBP2,HPS4,MPPE1" Drug 6820_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 42 176 "APLP1,ST3GAL5,RAB29,CLGN,NECTIN3,AKAP12,PDE4DIP,ARMCX2,RASGRP2,BAIAP2,FYN,CYP46A1,STON1,MXI1,NEK1,PDE4A,TMOD2,SERPINI1,PKIA,GRAMD1C,PRPH,PTCH1,GAL3ST4,RPS6KA2,SH3GL3,ASAP3,CPEB3,SYBU,WDR47,FAM214B,CCDC88A,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,SLC30A3,SLC17A7,ITM2C" Drug CID000004680 papaverine Stitch 2.11E-06 9.26E-02 8.90E-05 1.00E-03 42 176 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,AGT,PDE8B,ALDH7A1,DST,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CACNA2D2,PLCXD3,EDN1,ENPP6,INPP5K,PLCD4,GUCY1B1,HBA1,KCNH2,NPR2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PKD1,PLCB2,PLCD1,GDPD2,RYR3,SMPD3,TET1,PEG10,PLCB1" Drug 6771_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "SYN3,APBA2,MARK4,ADAM23,CFLAR,LDLRAD4,HAP1,ARHGEF1,CHGB,CHN2,STOML1,GREB1,DMPK,CELSR3,SUGP2,TNK2,VPS13B,FGFR1,FHL1,SIGLEC8,GLYR1,PRUNE2,GPER1,STMN2,CACFD1,IL6R,KCNJ5,KIT,MAP4,MBD1,MMP16,NCF2,PALM,PDE1C,PDE4A,MTRF1L,PLXNB1,NECAB2,C1orf54,AMBRA1,SLC14A1,ARHGEF9,SLC44A1,TNS1,PLPPR2,NT5M" Drug 3682_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "ASIC1,ADCY6,ALK,BEGAIN,APAF1,PPFIA3,BAIAP3,CAMK2B,SEPT7,B4GALT6,TAOK2,PLAA,IQCK,ENTPD4,SLITRK5,C2CD2L,PLPPR4,CDON,CNNM1,ETV1,FGFR1,PRELID3A,PCDH17,SPACA9,GRIK5,CACFD1,RASSF8,ATXN2L,KHK,MAPT,GIT1,OPRL1,PFKFB2,CEP41,PRKAR1B,SBF1,SCN8A,LIMS2,PKNOX2,FNBP1,SP4,DNMBP,CDK20,VLDLR,ZNF45,TFIP11" Drug 2543_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "BBOX1,AMH,BIN1,ATP2B2,AZGP1,RGS11,CACNA2D1,CACNB4,CAMK2A,CHRNA4,NRG2,HAPLN1,CRYBB1,ARHGEF10,BRINP1,HS3ST2,SEZ6L2,EDN3,TNK2,SRPK3,HSD17B14,ERBB2,GPD1,LILRA2,STMN2,GRIN2C,SOX21,RASSF8,ITGAM,PACRG,MATN2,MMP16,MPP2,PPP1R1A,RFX3,KCTD17,ASAP3,CCDC92,CLSTN2,ADGRL3,KIAA1107,DOCK9,TK2,OSBP2,WNT7A,ZBTB38" Drug 4837_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "AP2A2,KIAA1324,APC,ADGRB1,KSR1,CALB2,HAP1,FOXN3,FAM149A,CABP1,HAPLN1,AATK,OSBPL3,SNPH,DYNC1I1,EDN1,RASGRP2,PIPOX,PTK2B,FYB1,GNAL,GPD1,ATXN2L,ITGA7,KCNJ5,KHK,KPNA5,MEF2C,TAGLN3,NPTX1,NTRK3,ENPP2,SERPINI1,PPP2R2B,LRRN3,CNTLN,RGS12,FNDC3A,SNAP25,KDM4B,PEG10,IQSEC2,SYT5,WSCD1,PCDHGA10,NDRG4" Drug 3339_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "BIN1,CDC42BPA,BCAS1,PPP4R4,MARK4,NUMB,SLC4A4,CA4,CBFA2T2,SOCS6,TPP1,HOMER3,CSF1,USP6NL,PARD6A,DTNA,FEM1B,OPTN,ING4,STON1,CNTRL,SPACA9,CACFD1,ITPKB,KCNJ5,KHK,SLC11A2,CDK18,PRKAR1B,PRPH,WDR25,PTK2,PTN,CEP97,MORC4,RGS12,ANKRD6,IQSEC2,ELOVL4,PLCB1,MCF2L,KIAA0930,PCDHA6,AP4E1,ZKSCAN5,XRCC4" Drug 4082_DN Yohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "ASIC1,DNAH17,ATP1A3,ALDH7A1,NRP2,CACNA1I,AKAP5,PDE4DIP,ARHGAP24,BRINP1,MFAP3L,CHRDL1,CDON,CELSR3,ELN,MTSS1L,ST3GAL6,CGREF1,ZNF44,SRCAP,LPAR4,MAPT,MATN3,MYT1,NF1,NOVA2,SLC11A2,PDE4D,PIK3R1,PPARA,MINDY2,PTPRB,PID1,KHDRBS2,RGS4,DZIP1,SLC4A3,LIMS2,SNCA,ADGRL3,SYNE1,PCDHA5,TK2,TPM1,OSBP2,TIGD6" Drug 261_DN cyclosporine A; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "AK2,ALK,BIN1,BCAS1,RASL11B,ATP2B2,RAB29,HAP1,CH25H,CD38,ARHGAP33,B4GALT6,LHX2,RAB28,ARHGEF10,SIPA1L1,PPP6R2,DAPK1,GIT2,PLEKHA1,ING4,HSD17B14,STX2,ETV1,IQCG,ATP2C1,RUNDC3A,ZNF638,GNAO1,MCHR1,AP4S1,LAMA2,NPR2,NPTX1,NTRK3,PDE4D,RETREG2,CCDC40,RASGRF1,RGS3,RNH1,LIMCH1,HECW1,TBL1X,TMEM121,GPR161" Drug 4432_DN "estradiol, USP; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "RALGAPA1,LTBP4,BIN1,APC,APOC1,ATP6V0A1,ADAM23,MPDZ,BMPR1B,SCAPER,COL9A3,NRG2,SH2B1,HAPLN1,PHF14,EDIL3,MBNL2,EZH1,FGFR1,CINP,OGA,ARFIP1,TDRKH,GPER1,HSF2,INPP5B,KIF2A,MEIS1,MIA2,MMP16,ZNF862,CNOT4,PDE4D,PIK3R1,PLCB2,PTPRH,GTDC1,ASTN2,TBCEL,ZEB1,ZNF34,TMPO,VAV1,ZBTB14,ZNF32,PHTF2" Drug 3167_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "APLP1,LGR5,PPP4R4,ARHGDIG,ALDH7A1,N4BP2L1,ADGRB1,CFLAR,CDH2,ARHGAP33,EPS15L1,FAM149A,NCOR2,VCAN,DTNA,DTNB,MBNL2,TENM1,ELN,C3orf18,CORO2B,AGAP2,FLNC,SEPT9,GSN,IRAK3,VSIG4,IGF1,IL6R,KCNJ5,KPNA5,MSR1,TAGLN3,OPRL1,PCSK5,GPR85,SAMD9,PTPRD,LIMCH1,HECW1,NFASC,ARC,SYN2,PCDHA2,ADAMTS9,FAM13C" Drug 5621_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "ALCAM,AMH,SEMA7A,PRX,RGS20,CHRNA4,LHX2,EPS15L1,PICK1,EDNRB,PLXNC1,EPB41,ETV1,FGF13,FHL1,FYB1,GAD1,SIGLEC8,KCNN1,KIT,ZNF862,NEFM,NEK1,CNOT4,FAT4,KCNIP1,ASAP3,CPEB3,ST6GAL1,SLA,SLC2A5,CCDC88A,KIF13A,SYN2,WSCD1,ZEB1,HIF3A,TRO,UBE3A,UCHL1,XRCC4,SLC30A3,EVI5,GJC2,AP3B2,JPH3" Drug 4242_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "PKP4,APAF1,KCNAB2,PPP4R4,ATP2B2,ATP6V0A1,MTMR3,HAP1,SULT4A1,CSF1,LRIG1,PDE4DIP,MAML1,PARD6A,DNAH9,DTNA,IGSF6,PTK2B,DCTN2,ERGIC3,GRIK5,KCNN2,TM6SF1,NPTX1,FXYD1,PNMA3,CEP41,CNNM2,PTPRB,SH3TC2,C1orf54,GAL3ST4,ZMAT4,RNASEL,TCP11L1,RTN1,PKNOX2,OGDHL,SPTB,MCF2L,TAL1,TBCEL,CRTC1,HIRA,KCNAB1,EPM2A" Drug 2503_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "PDE8B,ATP1A3,BACH1,CACNA1G,CACNB4,CRLF1,CHRNA4,TAOK2,CREM,CRY2,RGS6,PDE4DIP,DZIP3,PITPNM3,FCF1,CELSR3,PLXNC1,ING4,FGFR3,PDLIM5,GATM,GSN,HAS2,SYNPO,MEF2C,AFDN,ADAM22,FSD1,PRKAR1B,RIPOR1,RTN1,SEMA6D,CCDC88A,TMCC1,PEG10,SPTAN1,ATP10B,TROVE2,TBCEL,TRIM2,AP4E1,GPR161,TIAM1,SSBP2,TUBB1,KCNAB1" Drug 1492_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "SYT13,AMT,CDC42BPA,CDC14B,MARK4,CFLAR,ST3GAL5,SCAPER,CA12,CACNA2D2,TAOK2,STOML1,NCOR2,FAM169A,ING4,FGFR3,BAIAP2,AHDC1,POLL,TDRKH,ADAMTS13,CACFD1,KCNH2,KCNN1,KIT,MAP4,MID1,PCDH9,CDK18,PLCD1,PMP22,SEC14L1,ZNF821,SH3BP2,ASAP3,CNKSR2,FAM214B,OGDHL,RBM34,HECW1,UNC5B,STX1A,IQCE,TCF4,CABIN1,SLC17A7" Drug 4959_DN Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "AK2,APC,BCAS1,CDK13,SCAPER,FOXN3,CLCN3,QKI,RAB26,SLC4A8,C2CD2L,MAMLD1,MRNIP,ENO2,EZH1,PRKAG2,PRELID3A,B4GALNT1,CRCP,CACFD1,MUM1,JAK2,IPO5,KITLG,NF1,NPR2,PLCD1,PRKAR1B,CNNM2,ELOVL2,SUSD4,ZCWPW1,RNASEL,ATXN2,LIMCH1,STX1A,ARHGEF9,EXOC7,RPGRIP1L,PARD3,TRIO,RUNDC3B,UBTF,VAV1,MPPE1,ST7" Drug 4505_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "BIN1,CDC42BPA,APC,SLC4A4,BACH1,SCAPER,CACNA1I,IL33,CFAP410,CAST,SYNGR3,PLPPR4,STX2,ETV1,CGREF1,GAD1,B4GALNT1,GNG4,TDRKH,GPR37,IL6R,IL6ST,KCNJ5,KIF2A,MEF2C,ZNF862,NDP,NFIX,NPR2,PIK3R1,PPARA,CSRNP3,SUPT20H,FBXO11,PPP4R3A,ZNF667,ARHGAP26,IQSEC2,TROVE2,VPS13A,COBL,TMPO,R3HDM1,FAM155A,XRCC4,EVI5" Drug 5761_DN Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-06 9.26E-02 8.90E-05 1.00E-03 46 200 "RALGAPA1,NME5,ALK,KCNAB2,CDC14B,ARNTL,CFLAR,MYRF,CFAP410,CA8,LARGE1,FOXN3,HINFP,PDE4DIP,PPP6R2,MFAP3L,RCAN1,EIF4G2,COQ7,FAM49B,ZNF276,GNG4,KCNH2,MAPT,SCAMP5,SETD4,MAPK7,GRAMD1C,GAL3ST4,SUPT20H,AMBRA1,SLC14A1,CDK5RAP2,SNCA,ARHGAP26,ZBTB43,SS18,TCF4,TNS2,GPR161,TNS1,TRIO,VGF,WIPF1,XRCC4,RNF146" Drug 4129_DN Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "NDRG2,ADORA2A,AMH,EPB41L5,FUBP1,CFAP410,ASIC3,CNTNAP2,MBNL2,ING4,ERCC2,FGFR1,DISC1,RAB30,FERMT2,GPD2,GRM8,RASSF8,IL6ST,INPP5B,KIT,MAP4,MAPT,MATK,NF1,NFYA,PLCD1,PTPRO,TCP11L1,RPS6KA2,FNDC3A,CCDC88A,COA1,SNAP25,SNCA,ZC3H13,THSD1,PLCB1,TBCEL,SMG6,AP4E1,THRA,TMPO,KAT6A,PHTF2" Drug 5610_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "LTBP4,APLP1,CFAP410,CAMK2B,CNTFR,CSF1,EGR3,EPHB1,ERCC2,FGF13,FGFR3,ERGIC3,ERAP1,GNAO1,SPACA9,FAM107A,GUCY1B1,KIFC3,MGAT3,MYO7A,NNAT,NPTX2,PDE4A,PFKFB2,POU6F1,PPP1R1A,LRRN3,MAPK7,MAPK10,PTPRD,RGS12,KCNIP1,SCN8A,ZNF821,FRMPD1,PKNOX2,KIF13A,WSCD1,ZEB1,CRTC1,R3HDM1,TRO,OSBP2,XRCC4,SLC30A3" Drug 4546_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "C1QTNF3,AMH,AMT,EPB41L5,GAS7,CDK10,ATP2B2,N4BP2L1,ATP6V0A1,FUBP1,MYRF,KALRN,HAP1,ARHGEF2,ARHGAP33,NRG2,VCAN,SPOCK2,MFAP3L,EDN1,ELN,RCAN2,ETV1,ZNF589,AFF2,ERAP1,ADAM28,GLI2,GNG4,ATXN2L,ICA1,LIFR,LMO2,NF1,PDE4D,PPARA,CCDC40,RGS12,ASAP3,PKNOX2,SNCA,COBL,ADGRL3,VGF,KCNAB1" Drug 4248_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "ACTN1,ADRB2,CDK10,ADGRB2,BCL7A,LHX2,RAB28,RAB26,NRG2,VCAN,HDAC9,CNNM1,OPTN,SUGP2,MTSS1L,STX2,EZH1,ST3GAL6,SEMA4D,PRELID3A,INPP5K,RUNDC3A,GLYR1,HMGCL,MID1,NLE1,MAPK7,ZCWPW1,KCTD17,FRMPD1,PPP4R3A,KANSL3,IQSEC2,CEP68,ASTN2,SMG6,SLC44A1,THRA,TNS1,RUNDC3B,AMACR,OSBP2,LMF1,WIPF1,NAV3" Drug 5952_DN radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "ADRA1B,BEGAIN,PPP4R4,NCOA1,NRP2,PROM1,FOXN3,SOCS6,LHX2,RAB33A,SH2B1,HAPLN1,NCOR2,AATK,TBC1D5,SPOCK2,EGFR,EIF4G2,NRN1,PRELID3A,GNG4,KCNN1,KIFC3,MEF2C,AFF1,MMP17,ZNF862,P2RY13,NFYA,OPRL1,PDE4B,GPR85,PFKFB2,SEMA6D,DZIP1,ARHGEF40,OGDHL,KDM4B,ZC3H13,COBL,PCDHGA10,CRTC1,GPR161,TNS1,OSBP2" Drug 6066_DN Skimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "NDRG3,AK2,ALCAM,SRPX,AMT,APBA2,FAM131A,MTMR3,GYG2,CBFA2T2,ARHGEF2,PICK1,CNTN1,ENTPD4,JAKMIP2,HIPK3,C3orf18,STX2,NCALD,ZNF589,FGFR1,IQCG,DISC1,SEPT9,TXNL4A,POLL,IL6ST,KPNA5,IPO5,LSS,MID1,MMP16,ADAM22,NF1,PDE4B,ZNF821,CDK19,ST5,KIAA0930,CHST8,HIRA,VIPR2,WIPF1,ZNF74,GDPD5" Drug 5055_UP Norethindrone [68-22-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "NDRG2,APBB2,APOC1,PRX,PPP4R4,PDE8B,BMPR1B,CACNA1I,CAPN3,LDB2,SCARB1,CACNA2D2,CREM,DTNB,SEMA3D,EIF4G2,VPS13B,MTSS1L,REEP2,OLFM1,FAM49B,SIGLEC8,SHISAL1,MX1,CNOT4,NTRK2,PDE4B,PPARA,MINDY2,LRRN3,ELOVL2,ZSCAN32,PID1,KIF13A,KDM4B,ZC3H13,PHLDB1,TBCEL,DNAH7,TLR4,RUNDC3B,ZNF74,REEP1,ZNF225,KCNAB1" Drug 2863_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "RALGAPA1,NDRG2,ADRA1D,BEGAIN,AMPD3,BIN1,KCNAB2,GAS7,CFLAR,GYG2,CA4,CAMK2B,SLC16A4,AKAP6,RUSC2,DNAH9,EDN1,EGFR,ELN,ERCC2,ANKMY1,REEP2,FGF1,SRCAP,GPER1,GSTM5,HLF,KCNQ3,ADAM22,NELL2,CNOT4,NPTX2,PPARA,C1orf54,KCTD17,BTBD7,LIMCH1,KDM4B,DOP1A,TSNAXIP1,IQSEC2,ARC,PARD3,KCNAB1,ITM2C" Drug 3173_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 45 194 "ASIC1,KCNAB2,CDK13,HIP1R,LDB2,SLC16A4,P2RX6,HOMER3,PCYT1B,CRMP1,MYEF2,FRY,C3orf18,LRRC17,NRN1,F5,CORO2B,DLC1,ZMYND10,FHL1,FYB1,CHL1,DISC1,ALDH1L1,ADAM28,GRM8,GSN,ATXN2L,KCNN1,KPNA5,SMAD1,MSR1,OPRL1,PCDHGC3,PFKFB2,PLCD1,ST6GAL1,ATP10B,TROVE2,PLCB1,R3HDM1,WIPF1,LAT2,NT5M,SLC17A7" Drug 6316_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.13E-06 9.33E-02 8.90E-05 1.00E-03 43 182 "ADRB2,NME5,EPB41L5,PPFIA3,SHROOM2,CDC14B,ARNTL,MARK4,ST3GAL5,HIP1R,USP2,NRXN3,WHRN,ABCG1,PDE4DIP,CTH,JAKMIP2,C2CD2L,PLPPR4,RGS17,TAOK3,NBEA,FYN,STON1,GUCY1B1,FAM69A,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,ENOX1,RGS4,FBXW7,SH3GL3,SPTAN1,THSD1,RGL1,SYT1,TRIM2,SSBP2,TRIM9" Drug 2208_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.13E-06 9.35E-02 8.91E-05 1.00E-03 44 188 "ABHD6,NDRG2,MTUS1,BIN1,CDC42BPA,APBB2,ST3GAL5,CFAP410,HIP1R,LHX2,AKAP6,CPS1,ABCG1,PDE4DIP,DOCK4,MAMLD1,VPS13B,ERBB2,ETV1,F5,DLL3,GATM,STON1,PCLO,ITGA7,KIF5A,NRCAM,PLCL1,PNMA3,PMP22,PPP2R2B,CRTAC1,SNCA,ZSWIM8,PEG10,STXBP1,TCF4,RPGRIP1L,TPM1,RUNDC3B,RPRM,KLC2,TRIM9,FZD3" Drug 2571_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 9.35E-02 8.91E-05 1.00E-03 44 188 "AMH,BIN1,APBB2,N4BP2L1,MYRF,CFAP410,CACNA2D1,PTBP2,USP2,CRLF1,CRY2,SLITRK5,DZIP3,RUBCN,RIPOR2,MFAP3L,EDNRA,PHC2,FAM13A,EGR3,C3orf18,TBC1D16,PTK2B,ZNF276,GPD1,PCLO,GSN,TJAP1,NEK1,FSD1,CNNM2,MARCH1,RFX2,SLA,SLC11A1,IZUMO4,SPTB,TROVE2,SAMSN1,SYNE2,ARHGEF9,CRTC1,HIF3A,PIK3R5" Drug CID000000119 gamma-aminobutyric acid Stitch 2.18E-06 9.55E-02 9.09E-05 1.02E-03 88 474 "ACHE,ADORA1,ADORA2A,AGT,SEMA6A,AMPH,APOC2,ARSE,ALDH7A1,KIF1A,BCS1L,CACNA1I,CACNA1G,CA4,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB1,CALB2,HAP1,CCK,CACNA2D2,SOCS6,CHRNA4,CLCN3,SULT4A1,CNR1,COL4A5,DBI,DLX1,DMPK,MED12,DTNA,MRO,GPHN,ERBB4,ZMYND10,PPP1R1B,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GATM,GLUL,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,GABARAPL2,IDH3A,KCNK3,MAP2,MAPT,MGAT3,NPY,NTRK2,OPRL1,PKD1,GPSM2,PRODH,RELN,APTX,PTCH1,RGS12,RIC8B,RYR3,SLC6A11,SLC12A2,SNAP25,SST,STX1A,VPS13A,SYN1,SYN2,SYP,TACR1,MLST8,ZEB1,SLC38A1,SLC17A7,WNK3" Drug 5247_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-06 1.07E-01 1.01E-04 1.13E-03 41 171 "NDRG2,SEMA6A,SRPX,APAF1,APBB2,APOC1,ARHGDIG,GYG2,CA12,LRRFIP1,B4GALT6,QKI,ENTPD4,SACS,ING4,RACK1,RAB40B,MIA2,KITLG,MMP16,NPTX1,NRCAM,PCDH9,PDCD2,PMP22,MBOAT7,PPP2R2B,TCP11L1,BTBD7,CDK19,TROVE2,KIAA0930,PCDHA6,ZMAT3,CBX5,METTL3,REEP1,SLC38A1,PHTF2,NETO2,GAN" Drug 1520_DN Azacyclonol [115-46-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "LTBP4,DOC2A,GAS7,APLP1,MARK4,KIF1A,GYG2,HAP1,CAMK2G,CRLF1,TAOK2,LHX2,SULT4A1,ARMC8,COL4A5,SH2B1,CSNK1E,MAML1,TMCC2,ACSL4,FER,PCYOX1,CSPG5,MALT1,GLYR1,SCAMP5,MMP16,NPTX1,MBOAT7,GTDC1,RGS12,GSTCD,MCMBP,FAM192A,SUPT20H,ASAP3,LIMCH1,MAPKBP1,KIAA0930,PCDHA6,PLPPR2,EMSY,ST7,SMIM8,PHTF2" Drug 4224_DN Benzocaine [94-09-7]; Down 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "MTUS1,SHROOM2,PDE8B,MARCH3,IQCK,CREM,ENTPD4,FAM169A,TBC1D5,DAPK3,MFAP3L,RUSC2,PLPPR4,CHRDL1,EXOG,FCF1,ETV1,RRAGB,ST3GAL6,FGF1,TRMO,GLI2,PCLO,HNMT,FAM69A,INPP5B,JAK2,LIG4,TAGLN3,RETREG1,TMEM231,BEND5,MAPK12,MRAS,FBXO11,FNDC3A,SPTAN1,CDK19,IQCE,TCF4,TK2,WIPF1,XRCC4,KCNAB1,PHTF2" Drug 7404_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ABR,PPFIA3,ADAM15,CAMK2G,CBFA2T2,TAOK2,SMARCAL1,SIPA1L1,SOCS5,DCAF8,DTNA,SUGP2,EPB41L2,CINP,OGA,TRAF3IP2,AHDC1,ZNF276,GLYR1,PADI2,ATXN2L,MAP4,MITF,NF1,NFYA,CNOT4,SLC25A23,PMP22,CEP97,ZCWPW1,ATXN2,SGK1,SH3BGR,FERMT1,AMBRA1,ABLIM3,CDK5RAP2,RCOR3,KDM4C,ELOVL4,CEP68,PHLDB1,ZNF106,KAT6B,RNF170" Drug 4326_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "DOC2A,PDE8B,ARHGEF1,SYNGR3,ARHGAP33,TAOK2,LY86,PICK1,NRG2,CRMP1,CSF1R,VCAN,PDE4DIP,SPOCK2,CHRDL1,DMPK,MBNL2,MRNIP,FGFR1,SEPT9,POLL,GPER1,TJAP1,IL6ST,INPP5B,MEF2C,LYRM9,NLE1,MAPK3,ELOVL2,PID1,ZDHHC14,MCMBP,SBF1,ASAP3,ZBTB43,LHPP,ZEB1,TK2,RPRM,PLPPR2,VIPR2,ZNF45,KCNAB1,PHTF2" Drug 2736_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "SLC4A4,SYNJ2,CACNA1G,CACNB4,DGKI,LARGE1,CDO1,CHN2,CNN3,CNTNAP2,BRINP1,KLHL3,PLXNC1,SRPK3,EPB41,ZNF549,DLC1,FHL1,EFCAB2,B4GALNT1,GCNT2,GNAL,SPACA9,GRM8,KCNN1,MAPT,MGAT3,AFDN,MYO6,NOVA2,NTRK3,PDE1C,PTPRN,RNASE1,SCN2B,SCN8A,FRMPD1,NLGN1,LIMS2,LIMCH1,ZNF415,PLCB1,TRIM2,PCDHGB6,UBE3A" Drug 5952_UP radicicol; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "MTUS1,OSBPL1A,NME5,EIF4G3,BID,CFLAR,SCAPER,CACNA1I,CBS,ARHGAP33,EPS15L1,ARMC8,CRY2,PDE4DIP,DZIP3,CTH,GIT2,FBXL5,DMPK,EDN1,ING4,ACSL4,ST3GAL6,BAIAP2,AFF2,CGREF1,ERAP1,GLI2,GLYR1,DIDO1,MUM1,SYNPO,MITF,NPR2,OXTR,SMIM7,PPARA,PTCH1,HSPA4L,PDZD2,ARHGAP26,ITPRID2,TRIM2,WIPF1,ZNF74" Drug 4262_DN Tolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ADCY6,MTUS1,PDE8B,ST3GAL5,SCARB1,CHN2,RAB26,HOMER3,WHRN,VCAN,PDE4DIP,FAM169A,SLITRK5,RUSC2,PLPPR4,DYNC1I1,DPH1,PLXNC1,ETV1,FGFR1,TRMO,PRELID3A,DENND2A,HNMT,SHISAL1,FAM69A,LIFR,LIG4,MIA2,TAGLN3,NDP,CCSER2,PLCD1,PRKAR1B,PRPH,PTPRN2,FAT4,FAM184A,ZDHHC14,FBXW7,FNDC3A,SLC4A3,TPM2,WIPF1,KAT6A" Drug 3821_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "DOC2A,PPP4R4,ZSCAN18,MPDZ,MYRF,SH2B1,PDE4DIP,SLITRK5,RIMS2,MFAP3L,CHRDL1,DUSP9,AASS,EIF4G2,NCALD,ZNF549,SCML2,FGF1,FYB1,NEU3,GPR75,GNG4,CACFD1,ITGA7,LAMA2,MPP2,LYRM9,NPR2,PDE4A,PDE4B,POLG,PTPRB,ZSCAN2,TCP11L1,RXRA,ASAP3,SLC6A11,SNCA,DOK5,KDM4C,ADGRL3,SLC44A1,TK2,TNS1,TRIO" Drug 6417_UP CGX 0596987; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ABHD6,ADCY6,APBB2,ARNTL,ARRB2,ADAM23,SYNJ2,CBS,ARHGEF2,CPS1,CSNK1E,VCAN,SGSM2,SUGP2,APH1A,EPB41L2,ETV1,FGFR1,PRELID3A,GPD2,STON1,DHX35,MKLN1,PDE4A,CCSER2,LRP12,PRPH,SAMD9,C1orf54,RXRA,MAPK12,SCN8A,SLC4A3,FAM214B,SIRT2,SLC22A4,IFT122,ST5,SYT1,IQCE,TBL1X,TIMP4,WBP2,MAP3K12,KAT6A" Drug 2382_UP Bufexamac [2438-72-4]; Up 200; 18uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "MTUS1,SPARCL1,AMPH,LGR5,PRX,CHRD,CACNA1G,CALB1,HOMER3,NRG2,CSF1R,KIAA0753,EIF4G2,ING4,CDKL3,SCARA3,PDLIM5,KHDRBS3,PCDH17,ATXN2L,ACOT7,ICA1,IL12A,KCNN1,KHK,MPP2,OPRL1,KCTD15,PMP22,RELN,CNTLN,RGS3,GALNT10,FERMT1,FBXO11,SLC8A1,KDM4C,SS18,STX1A,PDLIM2,TBCEL,FLRT2,MAP3K12,GDPD5,GAN" Drug 5911_DN valinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ASPHD1,ADRB2,MTUS1,APBB2,SHROOM2,CDC14B,DNAH17,ADAM15,BCL7A,MTMR3,ARHGAP33,B4GALT6,PDE4DIP,DAPK3,MFAP3L,SPOCK3,SGSM2,MAMLD1,NCALD,OLFM1,ITGA7,MAPT,MN1,NDP,PCDH9,PIK3R1,POLG,PPP5C,MAPK7,WDR25,SH3TC2,ZNF821,DZIP1,OGDHL,SNCA,SPTAN1,SPTB,COBL,MTCL1,KIAA0930,NACC2,TNS1,METTL3,NDRG4,SPHK2" Drug 268_DN genistein; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "APOC1,BCAS1,ARNTL,CHRD,GYG2,CFAP410,CAMK2A,CD86,CDH2,ARHGAP33,TAOK2,CSF1,KLHL3,DRP2,EDIL3,LRRC17,EYA1,SEPT9,SRCAP,RUNDC3A,GRM2,RNFT2,NCKAP1L,ATXN2L,C2orf72,TJAP1,L1CAM,MBP,MYO7A,MYT1,SEPT4,MASP1,PTPRN,MARCH1,GAL3ST4,EMID1,SLC8A1,SLC11A1,UNC5B,CLSTN2,POGZ,TACR1,CHST8,PLPPR2,VIPR2" Drug 5910_DN estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ASPHD1,ABHD6,ADRA1D,TRMT9B,APBB2,PPFIA3,CDK13,ATP2A2,ADAM15,CSF1,FAM131B,DAPK3,MFAP3L,SGSM2,CHRDL1,NCALD,PIPOX,ABCA8,OLFM1,ANKFY1,PRELID3A,FYB1,ERAP1,IL6R,MMP16,ADAM22,PCDH9,PDE4A,GPR85,GAL3ST4,RGS12,MRAS,CCDC88A,SNCA,RBM34,TSNAXIP1,SPTB,THSD1,SS18,COBL,EXOC7,DICER1,ICAM5,REEP1,TFIP11" Drug 7326_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ASPHD1,ABHD6,NME5,APAF1,APBB2,PDE8B,SLC4A4,ATP2A2,KIF1A,SCAPER,PICK1,NCOR1,FAM169A,MFAP3L,C2CD2L,EGFR,MRNIP,ERCC2,EZH1,ACSL4,DISC1,ALDH1L1,MSL3,GNG4,CNTRL,GRM8,GUCY1B1,ATXN2L,INPP5B,KPNA5,MIA2,MYT1,NF1,SLC11A2,MAPK7,SBF1,SYBU,SMARCD3,SNCA,RBM34,SOX3,SIK3,DICER1,AP4E1,KLC2" Drug 4122_UP Boldine [476-70-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ASPHD1,SPARCL1,ALCAM,AMPD3,GAS7,KSR1,CACNA1I,CLDN10,RAB33A,SULT4A1,COL9A3,LYPD1,SNX29,EGFR,MBNL2,VPS13B,MTSS1L,SCML2,DLC1,FHL1,DCTN2,OGA,SOX21,ICA1,KCNJ5,KCNN1,MATN3,ADAM22,NF1,NTRK2,RETREG1,GDPD2,GSTCD,TCP11L1,EMID1,RPS20,STUM,SH3BP2,ST6GAL1,SP4,PHLDB1,JMJD6,KIAA1107,HIF3A,PARP11" Drug 4170_DN Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ASIC1,AMPD3,GAS7,PLA2G4C,DNAH17,ALDH7A1,CACNA1I,CFAP410,CA4,HAP1,SLC16A4,FOXN3,CLTB,SNCAIP,CSF1R,PDE4DIP,SPOCK2,EDNRB,HIPK3,ERCC2,PIPOX,DLC1,ZNF589,DISC1,NEU3,ALDH1L1,TJAP1,JAK2,KCNN2,GIT1,ADAM22,NF1,SAMD9,C1orf54,TRIM68,SH3BP2,SH3GL3,KIF13A,TSNAXIP1,SYT5,TBCEL,KIAA0930,AP4E1,XRCC4,KCNAB1" Drug 7309_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ADD2,AMT,EPB41L5,CDK10,MARK4,SYNJ2,CAMK2B,RUNX1T1,CLTB,AKAP7,IQCK,CSF1R,VCAN,HDAC9,SPOCK2,DTNA,EGFR,EIF4G2,ING4,EPB41,MTSS1L,STX2,OGA,GRIK5,GUCY1B1,ATXN2L,TJAP1,ZNF862,CCSER2,RETREG2,MINDY2,KCTD17,EMID1,AMBRA1,TMCC1,KDM4C,DDN,SYT5,ADGRL3,TRIM2,DNAH7,TK2,VIPR2,VLDLR,KCNAB1" Drug 7135_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "AMPD3,PPFIA3,CDK10,CA12,PTBP2,CACNA2D2,LHX2,CPS1,DTNA,AASS,VPS13B,OLFM1,FGFR1,BAIAP2,AFF2,CINP,ERAP1,TMEM8B,SEPT9,MAN1B1,SYNPO,LSS,MEF2C,PCDH9,KCTD15,MAPK7,CNNM2,PTN,TMEM231,SH3TC2,GSTCD,MCMBP,SCN8A,FNDC3A,PEX26,SLC6A8,SNCA,POGZ,SYT1,DNAH7,TNS1,VGF,LMF1,WNT7A,UPF3A" Drug 3212_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ABHD6,NDRG2,PRX,ATP1A3,SLC2A11,ALDH7A1,CAMK2G,BAG4,NRG2,PDE4DIP,ARHGEF4,ARMCX2,DTNB,EDNRB,PLXNC1,SRPK3,ERCC2,CDKL3,AFF2,PRELID3A,FYB1,GPER1,GSN,KCNN1,MBNL1,ADAM22,TAGLN3,NEFH,NF1,NPR2,NTRK2,CDK18,TCP11L1,RPS6KA2,ASAP3,SLC2A5,PKNOX2,CXXC4,SS18,SMG6,WSCD1,TRIM2,DOCK9,PHTF2,RNF146" Drug 4174_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 45 195 "ADD2,AK2,ALK,BEGAIN,APBA2,APC,EPB41L5,GAS7,CHRD,ATP2B2,CFLAR,BAIAP3,CHN2,WHRN,CSF1,ARHGEF10,VCAN,CNTNAP2,HDAC9,ELMO1,EDN1,PLXNC1,TNK2,C3orf18,STX2,ANKMY1,FGFR3,AGAP2,FAM49B,SRCAP,SYNPO,PLCL1,MAPK7,PTCH1,RGS12,GSTCD,EMID1,PKNOX2,RBM26,LMO3,ATP10B,KIAA1107,DMXL2,DOCK9,NT5M" Drug 1645_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 42 177 "NME5,ARNTL,MARK4,ST3GAL5,BAIAP3,CLGN,ARMCX2,TSPAN5,OPTN,MBNL2,STX2,EXTL2,BAIAP2,FYN,CYP46A1,RAB40B,TDRKH,STON1,RNFT2,MXI1,NEK1,PCDH9,SERPINI1,PMP22,PKIA,PRPH,PTCH1,SH3GL3,PPM1E,ASAP3,WDR47,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,UBE2H,REEP1,SLC17A7" Drug 4665_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 42 177 "ABHD6,ADRB2,EPB41L5,ARNTL,MARK4,ST3GAL5,USP2,COL9A3,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,BAIAP2,FYN,STON1,SPACA9,GUCY1B1,BACH2,FAM69A,ITGA7,KITLG,MMP16,TAGLN3,PCDH9,SERPINI1,PRPH,ENOX1,RGS4,FBXW7,SH3GL3,KDM4B,DOP1A,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,COBL,HIRA,PLSCR4" Drug 6980_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 42 177 "ABHD6,NME5,ARNTL,ST3GAL5,SCAPER,SPAG9,CLGN,PDE4DIP,CTH,ARMCX2,ENO2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,FAM69A,INPP5B,LSS,MXI1,NEK1,PCDH9,SERPINI1,PKIA,PRPH,SH3GL3,PPM1E,WDR47,CCDC88A,SPTAN1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,REEP1,SLC17A7,ITM2C" Drug 6784_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 42 177 "NME5,SEMA6A,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,DOCK4,ARMCX2,JAKMIP2,ENO2,RASGRP2,STX2,FHL1,FYN,CYP46A1,STON1,MPP2,MXI1,NEK1,PDE4A,SERPINI1,LRP12,GRAMD1C,PRPH,PTCH1,SH3BGR,SH3GL3,ASAP3,WDR47,FAM214B,SMARCD3,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,REEP1,ITM2C" Drug 5209_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.47E-06 1.08E-01 1.01E-04 1.13E-03 42 177 "NME5,SEMA6A,MARK4,BMP7,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,ARMCX2,TMCC2,OPTN,RASGRP2,STX2,FYN,STON1,GRB10,MAP2,MPP2,MXI1,PDE4A,TMOD2,SERPINI1,GRAMD1C,PRPH,PTCH1,FAM184A,SH3GL3,ASAP3,WDR47,FAM214B,LIMCH1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,SLC17A7,ITM2C" Drug 2904_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.48E-06 1.09E-01 1.01E-04 1.13E-03 44 189 "ABHD6,NDRG2,BIN1,APBB2,ST3GAL5,SGCE,HIP1R,CDO1,CLGN,RAB26,CREM,NCOR2,ABCG1,DOCK4,MAMLD1,FAM13A,MRNIP,ETV1,FGFR1,FHL1,STON1,FAM69A,MYO6,ZNF862,NEK1,PCDH9,TMOD2,SERPINI1,PLCD1,SLC25A23,PMP22,POU6F1,TMEM255A,FAM184A,ANKRD6,SNCA,ELOVL4,RGL1,STXBP1,ZEB1,TPM1,CLIP2,SH3GLB2,FZD3" Drug 2710_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.48E-06 1.09E-01 1.01E-04 1.13E-03 43 183 "NDRG2,MTUS1,C1QTNF1,GAS7,DNAH17,ZSCAN18,ADGRB1,GYG2,CD86,CD38,CHN2,TAOK2,STOML1,CNTN1,CREM,ABCG1,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,ZFYVE16,MAMLD1,FAM13A,GALC,KIT,MEF2C,SCAMP5,MX1,NPTX1,CEP41,PID1,KCTD17,PBRM1,ARHGEF40,KIF13A,TMCC1,PEG10,DNMBP,PCDHGA10,CHST8,ZBTB38,SLC30A3,PLSCR4" Drug 7550_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.48E-06 1.09E-01 1.01E-04 1.13E-03 43 183 "ABHD6,ARNTL,BMP7,ST3GAL5,BAIAP3,SPAG9,USP2,SYNGR3,WHRN,PDE4DIP,GIT2,OPTN,BAIAP2,FYN,CYP46A1,RAB40B,GPR37,RNFT2,FAM69A,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,SLC25A23,PKIA,PRPH,PTCH1,QDPR,SH3GL3,PPM1E,SYBU,WDR47,SPTAN1,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,PLPPR2,SLC17A7" Drug CID000161645 oriens Stitch 2.70E-06 1.18E-01 1.09E-04 1.23E-03 38 154 "ACHE,ACTN1,ADORA1,ADORA2A,CA4,CALB1,CALB2,CCK,CHRNA4,PDCD6IP,GABRG1,GABRG2,GAD1,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SYNPO,KCNK3,KCNQ3,LSAMP,MAP2,NPY,NTRK2,NTRK3,RELN,SNAP25,SST,SYN1,ARC,SYN2,SYP,VSNL1,SLC17A7" Drug 2710_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ADRA1D,SRPX,ANK2,PPP4R4,NUMB,HIP1R,SCARB1,EPS15L1,IQCK,NRG2,CTH,HDAC9,MFAP3L,NR1D2,DTNA,C3orf18,EIF1,RASGRP2,CD320,DLC1,KHDRBS3,CSPG5,COPS8,GPR75,GNG4,MAP4,MATK,MEF2C,NNAT,SLC25A23,ZFHX4,MAPK12,PPM1E,FAM214B,SLC11A1,ZNF667,RBM26,DDN,TROVE2,CRTC1,TK2,PARD3,TNS1,CDK20,SPHK2" Drug 2534_DN Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "AMH,SLC4A4,ATP2A2,MTMR3,CACNA1I,LDLRAD4,KCNAB3,PICK1,ARHGEF10,VCAN,ARHGEF4,DAPK3,SPOCK3,EIF4G2,PIPOX,CAMKK2,ZNF44,SEPT9,ALDH1L1,CRCP,TJAP1,KHK,MAP4,MAPT,MGAT3,NF1,NINJ2,OPRL1,PDE4B,PLCD1,KHDRBS2,GALNT10,FRMPD1,CCDC92,SLC11A1,SNCA,DDN,JMJD6,TNS2,THRA,PARD3,FLRT2,XRCC4,MKRN3,EVI5" Drug 7251_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "C1QTNF1,ARRB2,MARCH3,SLC4A4,KSR1,MYRF,RUNX1T1,CD86,CRLF1,CNOT8,NRXN3,RUSC2,AASS,FGF13,FLT1,TRMO,OGA,GLI2,POLL,MAN1B1,TJAP1,FAM69A,KIF2A,KIFC3,ADAM11,PFKFB2,PIK3C2A,MAPK7,WDR25,ZSCAN2,SBF1,PPP4R3A,FAM214B,TMCC1,ZBTB43,SS18,SEPT8,CEP68,SYT1,SZT2,HIRA,WNT7A,ZNF711,EMSY,EPM2A" Drug 2232_DN Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "APBA2,APC,SYNJ2,MTMR3,CACNA1I,CACNA1A,MAGI1,RCBTB2,FOXN3,ARHGEF6,CSF1R,PDE4DIP,SEC14L5,CDON,SLC12A6,EIF4G2,STX2,FAM49B,MPP6,POLL,IL6ST,NF1,NFYA,CDK18,MBOAT7,PRODH,PTN,RGS3,TCP11L1,RPS6KA2,KDM4B,DOK5,UNC5B,ARHGAP26,IQSEC2,THSD1,VPS13A,PLCB1,TNS2,TRIO,FAM155A,FLRT2,PLPPR2,ZNF74,ST7" Drug 3394_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "RALGAPA1,ADORA2A,KIAA1324,N4BP2L1,CFLAR,CACNA1I,HIP1R,RHBDL1,RUNX1T1,ARHGEF2,FAM169A,DGKG,DAPK3,SNX29,PLXNC1,TNK2,ERCC2,REEP2,FHL1,GAD1,SIGLEC8,DISC1,GRB10,GRIK5,ICA1,INPP5B,KIT,MAP4,MEF2C,ADAM22,MX1,PPP5C,CEP41,CCDC40,RFX2,PKNOX2,ARHGAP26,PCDHGA10,SYNE1,R3HDM1,XRCC4,PLSCR4,EPM2A,PHTF2,SENP7" Drug 3732_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "NME5,APAF1,APC,GAS7,DNAH17,RASL11B,STX16,NRP2,BAIAP3,CDO1,TAOK2,HAPLN1,MYEF2,EXOG,HS3ST2,SEMA3D,HPCAL4,IQCG,ADAM28,C2orf72,TJAP1,ITPKA,KIFC3,MAN2A2,PCBP3,PALM,PDE4D,PLXNB1,CCDC40,FAM184A,ZMAT4,CARF,RPS20,ZNF821,NLGN1,ZNF667,IQSEC2,PLCB1,COBL,TRIM2,TK2,BHLHB9,ZNF154,KCNAB1,PLSCR4" Drug 4479_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "NDRG2,ADORA1,APAF1,GAS7,AQP6,BAIAP3,RUNX1T1,NCOR2,DTNA,SEMA3D,EGFR,PLXNC1,NCALD,F5,AFF2,CSDC2,GNAO1,GRM8,KCNB1,KCNF1,KCNN1,SMAD1,MAN2A2,MSR1,NF1,NTRK2,PDE4B,PDE4D,PLCB2,POU6F1,RET,KCTD17,RPS20,KANSL3,PKNOX2,SLC11A1,TSNAXIP1,ARHGAP26,MCF2L,SMG6,TK2,ICAM5,TNS1,OSBP2,KCNAB1" Drug 5884_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "NME5,BMP7,CACNA1G,PLEKHB1,STOML1,QKI,LY86,RCHY1,PDE4DIP,GPRASP1,TBC1D5,GIT2,HEPH,MFAP3L,RUSC2,EXOG,EDN1,CNNM1,EIF4G2,HSD17B14,FAM198B,SCARA3,FYB1,POLL,LAMA2,NF1,NTRK2,SAMD9,ENOX1,KCTD17,NEK11,ASAP3,PKNOX2,ZNF334,ELMO2,TMCC1,SPTAN1,DDN,TACR1,EXOC7,CABIN1,TNS1,XRCC4,REEP1,DPF3" Drug 5109_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ADORA1,AGT,TRMT9B,APC,GAS7,NRP2,HAP1,VAX2,AKAP5,SEC14L5,MFAP3L,RUSC2,DMD,DTNA,MRNIP,FGFR1,AGAP2,ERGIC3,GNAO1,TDRKH,SYNPO,PACRG,ADAM22,MX1,NF1,NNAT,PPP5C,C1orf54,ENOX1,RGS4,KCTD17,PNMA8A,ASAP3,CNKSR2,SLC2A5,ARHGEF40,ZNF334,DOK5,TROVE2,TAL1,PCDHA5,TLR4,TNS1,SPHK2,PARP11" Drug 2726_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASPHD1,BEGAIN,SLC4A4,SGCE,CACNA1I,CFAP410,RHBDL1,CDO1,CNR1,AKAP6,CREM,AATK,CSF1,BRINP1,SPOCK3,FGFR1,FHL1,PRELID3A,INPP5K,PCDH17,LILRA2,GUCY1A1,ICA1,TJAP1,KCNH2,MGAT3,CNOT4,PLCD1,CEP41,PKIA,CNNM2,WDR25,PBRM1,PLPPR3,FERMT1,CPEB3,SYBU,PKNOX2,TMCC1,SOX15,SSTR2,TCF4,PCDHGA10,LMF1,PRDM10" Drug 3705_DN Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "MTUS1,ADGRF5,PKP4,APC,APOC1,ADGRB2,ST3GAL5,PLAA,ABCG1,CTH,HDAC9,DAPK3,CHRDL1,RCAN1,ING4,COQ7,DENND4A,RRAGB,FGF1,PDLIM5,TRAF3IP2,GUCY1B1,HSF2,INPP5B,JAK2,LIG4,MBNL1,TAGLN3,MX1,LRP12,SAMD9,KCTD17,OGDHL,TROVE2,ARHGEF9,KIAA1107,TBCEL,TCF4,TRIM2,SZT2,TRIO,SSBP2,UGT8,TFIP11,SMIM8" Drug 7338_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "NME5,APAF1,ARRB1,KIF1A,CFLAR,CAMK2G,SLC16A4,TAOK2,TPP1,HOMER3,AKAP7,DOCK4,FCF1,F5,FAM49B,PRELID3A,GPR37,GRIK5,BTN2A1,PADI2,ATXN2L,HNMT,SMAD1,MAPT,MMP16,NF1,SBF1,ZNF821,RASA3,FNDC3A,SNCA,RBM34,ARHGAP26,ZNF302,ST5,TTBK2,VPS13A,TRIM2,OBSL1,ZNF34,SLC44A1,R3HDM1,UBE3A,HPS4,ACTR3B" Drug 2491_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "MTUS1,BEGAIN,ARHGDIG,ATP2B2,BMP7,CACNA1G,CBFA2T2,CDO1,CACNA2D2,TPP1,RAB26,NCOR2,CRYM,CSNK1E,PPP1R16B,DCAF4,EDNRA,VPS13B,RASGRP2,STX2,CDKL3,AGAP2,CAMKK2,HPGDS,GLYR1,GRIK5,IL12A,MAPT,AFDN,MMP17,MPP2,ADAM22,MSR1,MX1,NOVA2,CCSER2,PLCL1,GDPD2,MARCH1,PID1,DOP1A,SP4,ZC3H13,CUX2,FAM155A" Drug 6873_UP "H-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ACTN1,SEMA4G,ARNTL,ALDH7A1,BCHE,HIP1R,CBFA2T2,CRLF1,SOCS6,LHX2,NRXN3,ARMC8,CSF1,RIMS2,PYGO1,GIT2,RUSC2,PLPPR4,CNNM1,CELSR3,MRNIP,AFF2,DISC1,GLYR1,NCKAP1L,ATXN2L,SHISAL1,KCNH2,KCNQ3,NF1,NOVA1,PFKFB2,DUSP26,PRKAR1B,MAPK3,KCNIP1,PEX26,FAM214B,PLCB1,TACR1,KIAA1107,CDK20,VGF,ZNF74,GAN" Drug 1708_DN Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASPHD1,AP2A2,LTBP4,APBB2,CFLAR,BMP7,ARHGEF7,EIF5,FER,FGFR1,FGFR3,BAIAP2,NOP56,OGA,AHDC1,MALT1,HTATSF1,DHX35,ICA1,MAP4,MBD1,MITF,GIT1,NPR2,RIPOR1,DCUN1D2,RPS6KA2,FERMT1,FAM214B,ZBTB43,KIAA0930,TRIM2,CRTC1,PCDHA6,CHST8,CABIN1,CDK20,HIRA,UBE3A,PLPPR2,VAV1,KLC2,ZBTB14,EMSY,SMIM8" Drug 6647_UP Estrone [53-16-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASPHD1,KCNAB2,PPP4R4,ARRB1,ZSCAN18,BACH1,HAP1,SCARB1,CHRNA4,SULT4A1,AKAP6,MFAP3L,C2CD2L,DTNA,IGSF6,ETV1,DLC1,OLFM1,GABRG2,NEU3,RUNDC3A,STMN2,CACFD1,ITGA7,KCNB1,LSS,ADAM22,MYO7A,NELL2,NRCAM,P2RX7,PDE4B,ZSCAN32,PTPRO,ENOX1,RNASEL,FBXW7,SNCA,SP4,SPTB,PCDHGA10,HIF3A,R3HDM1,TPM1,ZNF24" Drug 7025_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "AP2A2,AK2,APLP1,ARHGDIG,SYNJ2,CA4,PLEKHB1,B4GALT6,VAX2,PICK1,BAG4,RGS6,LRIG1,HDAC4,DMTF1,DTNA,F8,FAM198B,GRIK5,MUM1,IL6R,ITPKB,IPO5,LSS,MAP4,CNOT4,PRODH,DCHS2,SAMD9,VPS13C,CCDC40,KHDRBS2,SH3BP2,FBXO11,PEX26,FAM214B,KANSL3,PLCB1,SYT5,PCDHA5,PIK3R5,UBE3A,KCNK12,HPS4,MARCH8" Drug 4360_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ADRA1D,SYT13,OGT,APBB2,GAS7,CALB1,CLDN10,RCBTB2,QKI,SULT4A1,DOCK4,DAPK1,SPOCK2,APC2,RASL12,FYN,GNAO1,NXPH3,HLF,IRF8,KCNB1,KCNH2,MAN2A2,MSI1,PALM,POU6F1,PPARA,CEP41,PNMA8A,SH3BP2,SLA,ZNF423,ATP10B,SYN2,WSCD1,ZEB1,TIMP4,R3HDM1,UCHL1,CLIP2,MKRN3,NT5M,TIGD6,DPF3,AP3B2" Drug 6880_UP BAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASPHD1,AP2A2,ALCAM,BIN1,FAM131A,BAIAP3,CFAP410,FOXN3,QKI,CSNK1E,DZIP3,HS3ST2,DTNA,TOM1,EGFR,FGF1,CGREF1,GLYR1,MSL3,POLL,MUM1,HNMT,MYO9A,ZNF862,TREM2,PIK3R1,PRKACB,GSTCD,TCP11L1,SBF1,FBXO11,MAPKBP1,TMCC1,ZHX3,SS18,ELOVL4,ARHGEF9,VPS13A,RPGRIP1L,ICAM5,TSN,KLC2,SLC30A3,SEMA3B,MPPE1" Drug 6653_DN Bezafibrate [41859-67-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "APOC1,FOXN3,HAPLN1,CNTNAP2,GIT2,MBNL2,PLXNC1,TENM1,EPB41L2,CDKL3,ZNF589,ANKFY1,SEPT9,SRCAP,GLYR1,KCNMB4,GPR37,KHK,MEIS1,MMP16,LYRM9,NF1,CNOT4,PLCD1,PLXNB1,MAPK7,CNNM2,CNTLN,PID1,ZCWPW1,NEK11,RPS6KA2,ZNF821,ZFP30,ASAP3,IQSEC2,CEP68,SYT1,SMG6,SLC44A1,TRIO,VGF,XRCC4,HPS4,PHTF2" Drug 3108_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASIC1,AGT,FAM135A,PROM1,BMP7,FUBP1,GYG2,CAPN3,STOML1,RAB26,PICK1,SLC4A8,CPS1,ABCG1,CRYM,PDE4DIP,USP6NL,SPOCK3,BAIAP2,FYB1,ALDH1L1,GCNT2,RASSF8,PADI2,TJAP1,ITPKA,KCNN1,AFDN,MPP2,CLDN11,PFKFB2,PLCL1,MAPK3,MASP1,RASA3,FAM102A,SLC11A1,IZUMO4,ATP10B,ST5,PLCB1,ADGRL3,DOCK9,PCDHA2,KLC2" Drug 3187_DN Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "AK2,TRMT9B,AMPD2,CDC42BPA,APC,CDK10,SEMA4G,ATP6V0A1,RIPK1,SCAPER,CAMK2G,TAOK2,AKAP7,CREM,AKAP12,FGFR1,ANKFY1,ZNF44,ERAP1,TXNL4A,ITPKB,KCNH2,LMO2,MAP4,SCAMP5,CNOT4,SLC25A23,MINDY2,ZCWPW1,GSTCD,SBF1,SGK1,AMBRA1,KIF13A,ST5,STX1A,MTCL1,MCF2L,DOCK9,TNS2,CRTC1,TK2,PLPPR2,VIPR2,HPS4" Drug 6638_DN beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "ASIC1,BIN1,AMT,APBB2,CDK13,DNAH17,SLC4A4,SCARB1,PICK1,WHRN,DZIP3,DMPK,FAM13A,AASS,TUBD1,COQ7,ZNF549,ETV1,ZNF589,FGFR1,POLL,GPER1,KHK,KPNA5,CNOT4,PIK3R1,GRAMD1C,SNRK,PID1,BEND5,ASAP3,ANKRD6,SMARCD3,IQSEC2,DDN,SS18,CRTC1,BEX4,PARD3,SSBP2,ZKSCAN5,UBTF,NT5M,SMIM8,PHTF2" Drug 3692_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "SEMA6A,CDC14B,N4BP2L1,BMP7,FUBP1,CACNA1I,CBS,NRXN3,SULT4A1,PCYT1B,COL9A3,HAPLN1,ABCG1,CSF1R,CNTNAP2,C2CD2L,HIPK3,RGS17,IGSF6,DLC1,ZNF589,ANKFY1,SYT17,SCIN,ITPKA,KCNJ5,KCNN1,MEF2C,NNAT,FSD1,PTPRN2,SUSD4,S100B,SLC6A11,ARHGEF40,ELMO2,CXXC4,SPP1,PLCB1,SYT5,CRTC1,GPR161,TNS1,ZNF154,VPS35L" Drug 4741_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "AP2A2,ADGRF5,SEMA6A,AMPD3,BIN1,APOC1,SEMA4G,AZGP1,CFAP410,CDH2,CNN3,AKAP7,HAPLN1,RASSF2,RUSC2,SPOCK3,DMPK,FHL1,SIGLEC8,GLI2,GNAL,GPR37,SPACA9,GRM8,GUCY1B1,VSIG4,TJAP1,KCNH2,KCNJ5,AFDN,ADAM22,MYO7A,PLTP,LRP12,PTPRB,C1orf54,FRMPD1,CNKSR2,KANSL3,IZUMO4,ATP10B,ST5,CHST5,TRPM2,XRCC4" Drug 2925_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "APBB2,APC,CDK10,CDK13,C5,CAPN3,KRIT1,SOCS6,RCHY1,PDE4DIP,DCTN1,ZNF804A,DTNA,EGR3,EIF1,FYB1,ERAP1,LILRA2,ATXN2L,MAP4,MEF2C,RETREG1,SAMD9,SNRK,TMEM104,ZSCAN32,RET,FBXO11,ARFGAP1,ZNF667,MYH15,IZUMO4,ITPRID2,JMJD6,DNMBP,TBL1X,ZMAT3,KAT6B,TNS1,TPM1,TPM2,SMUG1,UBE3A,SPHK2,NT5M" Drug 2101_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "MTUS1,APC,SLC4A4,ALDH7A1,HIP1R,SOCS6,ARHGAP22,CLCN3,ABCG2,RAB26,CSF1R,SLITRK5,PPP6R2,GIT2,SGSM2,DMPK,DTNA,ETV1,CORO2B,FGF1,GFER,MSL3,STON1,PCLO,GSTM5,RNFT2,KCNN1,MEIS1,NFYA,C1orf54,SUGCT,ZFP30,CCDC88A,TSNAXIP1,ERC1,ARHGAP26,ZBTB43,PHLDB1,COBL,IQCE,RPGRIP1L,PCDHGA10,LAT2,KCNAB1,ADAMTSL3" Drug 4490_UP Piretanide [55837-27-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.85E-06 1.25E-01 1.13E-04 1.27E-03 45 196 "MTUS1,AK2,BEGAIN,APAF1,EPB41L5,BCAS1,CDK13,ATP2B2,ADAM23,BMPR1B,GYG2,CBS,TAOK2,ABCG2,HOMER3,COL9A3,NCOR2,EXOG,DMPK,ETV1,PTK2B,AGAP2,FYN,LYVE1,KCNN1,LSS,SMAD1,NEFM,NF1,NPR2,CDK18,GPR85,PFKFB4,PIK3R1,NLE1,PPP2R2B,MAPK7,SNRK,EMID1,RPS20,DZIP1,HECW1,MCF2L,KCNAB1,GAN" Drug 2330_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.86E-06 1.26E-01 1.13E-04 1.27E-03 41 172 "NME5,ALCAM,CDC14B,ARNTL,ST3GAL5,BAIAP3,CLGN,WHRN,SEC14L5,ARMCX2,JAKMIP2,OPTN,RASGRP2,STX2,ZNF589,FYN,CYP46A1,RAB40B,STON1,MITF,NEK1,PCDH9,SERPINI1,GRAMD1C,PRPH,SH3GL3,PPM1E,ST6GAL1,PKNOX2,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 5217_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.86E-06 1.26E-01 1.13E-04 1.27E-03 41 172 "NME5,ST3GAL5,BAIAP3,USP2,SLC16A4,CLGN,CRY2,PDE4DIP,ARMCX2,TMCC2,OPTN,MBNL2,BAIAP2,FYN,CYP46A1,STON1,KCNN2,MAP2,MXI1,NEK1,PCDH9,SERPINI1,GRAMD1C,PRPH,GAL3ST4,SH3GL3,ASAP3,WDR47,FAM214B,PKNOX2,SPTAN1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SLC30A3,SLC17A7" Drug 3257_UP Apigenin [520-36-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-06 1.26E-01 1.13E-04 1.28E-03 44 190 "KIAA1324,BIN1,FUBP1,CACNA1I,BAIAP3,CFAP410,CBFA2T2,CDH2,QKI,CRY2,EGR3,LRRC17,CDKL3,FAM198B,AMOTL2,TRAF3IP2,SESN1,RUNDC3A,GPER1,DIDO1,FICD,ITGA7,MAP4,ADAM22,ZNF862,PLCD1,SMIM7,PLTP,PPP5C,RET,DCUN1D2,RPS20,ZFP2,PREX2,COA1,SNCA,DOK5,PEG10,ZBTB43,SYN2,ZMAT3,ZNF34,VIPR2,SEMA3B" Drug 5940_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.88E-06 1.26E-01 1.14E-04 1.28E-03 42 178 "ABHD6,ADRB2,AP2A2,NME5,ARNTL,MARCH3,ST3GAL5,HIP1R,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,TBC1D16,TAOK3,BAIAP2,NBEA,FYN,STON1,SCIN,FAM69A,ITGA7,MAP2,MAPT,PCDH9,ENPP2,SERPINI1,PRPH,PTCH1,RGS4,RPS6KA2,SH3GL3,KDM4B,ARHGAP26,ELOVL4,RGL1,ARC,SYT1,RUNDC3B,SSBP2,TRIM9,PLSCR4" Drug 2702_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,APAF1,MADD,CLGN,CSF1,ARHGEF10,CSNK1E,SLITRK5,CTH,DAPK3,SV2B,CNNM1,ELN,CORO2B,KAT8,NBEA,INPP5K,ALDH1L1,ZNF276,GRB10,PADI2,ATXN2L,LIG4,MYH3,MYO6,PDE4A,FSD1,CNNM2,BCAS3,CEP97,RPS6KA2,GALNT10,CCDC92,ANKRD6,PREX2,EPN2,IZUMO4,IQSEC2,LHPP,KAT6B,TNS1,CDK20,SMUG1,FLRT2,CLIP2" Drug 5643_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "C1QTNF3,DOC2A,AMH,N4BP2L1,ADGRB3,KSR1,FUBP1,CA4,ARHGEF1,RAB33A,CPS1,DZIP3,DTNA,DTNB,ING4,REEP2,FGF13,FGFR3,FLNC,RUNDC3A,PRUNE2,STON1,LPAR4,SPACA9,GRM8,HNMT,SMAD1,AFDN,MYCN,NF1,NTRK3,PFKFB2,WDR25,PTPRE,ZSCAN2,OGDHL,SNCA,CDK19,RBM26,ATP10B,ICAM5,R3HDM1,FLRT2,XRCC4,SLC30A3" Drug 6803_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "AGT,AMPD3,ATP2B2,CACNA1I,CA4,STOML1,LY86,DAPK3,DBN1,PARD6A,EDNRA,EDNRB,TNK2,OLFM1,FGFR3,FHL1,HPCAL4,PDLIM5,DLL3,TRAF3IP2,SRCAP,GFER,GNAO1,CACFD1,IL6R,KCNN1,MEF2C,NPTX1,LRP12,CNTLN,ZMAT4,SUGCT,TCP11L1,EMID1,SBF1,MRAS,FRMPD1,UNC5B,IQSEC2,TCF4,GPR161,KCNK12,XRCC4,EPM2A,FAM13C" Drug 460_DN deferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,APBA2,CAMK2G,TBRG4,CREM,SACS,SUGP2,ETV1,DLC1,FAM49B,TRAF3IP2,ZNF274,ARFIP1,DBF4,SMAD1,MBD1,MBNL1,CNOT4,NPTX1,SLC11A2,PCDH9,GPSM2,VPS13C,QDPR,SH3TC2,REV3L,ROBO1,ZC3H14,SUPT20H,R3HDM2,ELMO2,FNBP1,ERBIN,CEP68,IQCE,TBL1X,TCF4,ZEB1,TRIM2,TMPO,WIPF1,ZBTB38,RNF103,SLC17A7,FIP1L1" Drug 4231_DN Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "RALGAPA1,CDK13,PDE8B,SLC4A4,ADAM15,HOMER3,ENTPD4,CSNK1E,VCAN,CNTNAP2,DTNA,TOM1,EDN1,FCF1,FAM13A,MBNL2,STX2,ZNF589,FGFR1,RUNDC3A,GLYR1,TDRKH,INPP5B,KCNN1,LSS,NEK1,PDE4B,PIK3R1,MINDY2,KCTD17,GSTCD,FBXW7,TRAPPC13,SAFB,CSRNP3,ZNF821,PPP4R3A,TRIM2,GPR161,SLC44A1,THRA,TPM2,AMACR,REEP1,KCNAB1" Drug 4421_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASIC1,NDRG2,GAS7,CDC14B,CDK13,ATP2B2,ADAM15,RHBDL1,ASIC3,SNCAIP,RGS6,DUSP9,TNK2,RASGRP2,F5,ZNF589,FHL1,GAD1,ALDH1L1,MSL3,GPER1,GRIK5,GUCY1B1,JAK2,KIF5A,MMP17,MYO7A,NPY,PCBP3,CLDN11,PPARA,CEP41,C1orf54,SCN8A,RASA3,SLC14A1,DOK5,PCDHA5,HIF3A,GPR161,LAT2,KCNK12,SLC30A3,PARP11,PHTF2" Drug 2780_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "FAM131A,CDK13,NUMB,STX16,GYG2,SOCS6,QKI,RCHY1,BAG4,NR1D2,HIPK3,MBNL2,SCML2,FER,FGFR1,PDLIM5,DISC1,INPP5K,RASSF8,KPNA5,MATK,KITLG,MMP16,ZNF862,SETD4,LRP12,RAD51D,ZCWPW1,RNASEL,ROBO1,TCP11L1,SH3BGR,SLC6A8,BTBD7,SMARCD3,KDM4C,CDK19,NXT2,ANKRD12,KIAA1107,ZNF34,TIAM1,DNALI1,UBE3B,PHTF2" Drug 224_DN retinoic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,ADD2,AK2,ALK,APBA2,GAS7,NCOA1,MYRF,AATK,DYNC1I1,DRP2,EGR3,EIF4G2,COQ7,STX2,FGFR1,TRMO,CYP46A1,RUNDC3A,GNAL,NCKAP1L,LAMA2,MARK1,GIT1,NF1,SLC11A2,PCDH9,PLEC,FXYD1,GAL3ST4,CRTAC1,SUPT20H,FERMT1,ABLIM3,PPP4R3A,ARHGEF40,SIRT2,CDK5RAP2,SNCA,TROVE2,COBL,SSBP2,PLPPR2,ZNF23,ZNF32" Drug 4137_DN Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,NME5,AK2,LTBP4,BIN1,APBA2,APBB2,PDE8B,NCOA1,C5,EPS15L1,C2CD2,SIPA1L1,HDAC4,TBC1D5,C2CD2L,DTNA,EGR3,KAT8,FHL1,GRB10,SPACA9,ITPKB,MAP4,MBD1,MPP2,ADAM22,NEK1,SETD4,RETREG1,TMEM104,ZDHHC14,TCP11L1,SEMA6D,SH3BP2,PPM1E,KDM4B,ZHX3,TROVE2,JMJD6,MCF2L,CLASP1,PARD3,WRN,ZIC1" Drug 4160_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYT13,APBA2,GAS7,ATP2B2,KSR1,RUNX1T1,CDH2,TAOK2,CNTNAP2,ARHGEF4,HDAC9,MYEF2,DMPK,FAM13A,EGFR,CALCRL,CORO2B,OGA,SIGLEC8,RUNDC3A,LPAR4,GRIK5,ITGA7,MEF2C,ADAM22,GPR85,MAPK7,GDPD2,PTCH1,TMEM255A,RGS4,TRA2B,ST6GAL1,CNKSR2,DZIP1,KANSL3,PKNOX2,WSCD1,TNS2,SLC35G2,DNAH7,TRIO,KCNK12,ITM2C,PHTF2" Drug 2826_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "RALGAPA1,NDRG2,KIAA1324,NRP2,CFLAR,BAIAP3,CAMK2B,CAST,KYAT1,ARHGAP33,FOXN3,TAOK2,PICK1,SIPA1L1,EXOG,TOM1,DUSP9,OPTN,PLXNC1,NCALD,ZNF589,FGFR1,SCARA3,GAD1,NEU3,RUNDC3A,GNG4,SPACA9,IPO5,MITF,TAGLN3,MYO7A,PCDH9,PDE4D,PFKFB2,EMID1,KCNIP1,RASA3,SH3BP2,PREX2,ARHGEF40,HEY1,TIMP4,FAM155A,ST7" Drug 3315_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "BEGAIN,CDC42BPA,FAM131A,CFLAR,CACNA1I,BAIAP3,ARHGAP33,FOXN3,TPP1,WHRN,ENTPD4,CSF1R,CNTNAP2,GREB1,ARHGEF4,EIF4G2,BAIAP2,SEPT9,POLL,RASSF8,IL6ST,KHK,MAP4,MMP17,ADAM22,NPR2,CLDN11,PLCD1,MINDY2,PRKACB,ZSCAN2,TMEM231,KCNIP1,ASAP3,KDM4D,SLC9A5,PHLDB1,ARC,KIAA1107,FLRT2,WIPF1,KCNK12,MKRN3,DNALI1,KCNAB1" Drug 6138_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "DOC2A,CDC42BPA,RGS11,SYNJ2,MYRF,CFAP410,CACNB4,HAP1,SLIT2,DCAF4,ARHGAP32,DGKG,PLPPR4,HIPK3,OPTN,EIF1,STX2,ERBB4,AGAP2,CAMKK2,GCNT2,RUNDC3A,GNAO1,GRM8,MBP,MGAT3,MMP17,MYT1,TREM2,PCDH9,PDE1B,KLK6,RASGRF1,RFX2,CXXC4,ZSWIM8,IZUMO4,ARHGAP26,TROVE2,EXOC7,CHST5,UBE3A,VGF,MKRN3,SLC17A7" Drug 2786_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,NME5,KIAA1324,BIN1,KCNAB2,MTMR3,BAIAP3,CBFA2T2,RCBTB2,ASIC3,TAOK2,EPS15L1,HOMER3,AKAP7,SNPH,DMPK,CDON,C3orf18,ZNF589,GFER,ICA1,KCNB1,KCNN1,MAP4,MAPT,OPRL1,PLCD1,PPP5C,RELN,PTPRN2,ENOX1,RPS6KA2,SCN8A,STUM,KDM4B,ZC3H13,ARC,SYN2,WSCD1,PCDHGA10,TK2,FLRT2,TFIP11,SEMA3B,SLC17A7" Drug 3031_DN Rolitetracycline [751-97-3]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADORA2A,APAF1,APBB2,APOC1,CDK10,NCOA1,KIF1A,SCAPER,LDLRAD4,HIP1R,KYAT1,CD86,B4GALT6,EPS15L1,TPP1,SH2B1,RUSC2,CDON,DTNA,MBNL2,EIF5,ING4,STX2,FER,INPP5K,LILRA2,SPACA9,SLC2A6,NCKAP1L,ATXN2L,NF1,PLEC,SLC25A23,PRKAB2,SEC14L1,RASA3,FBXO11,ARFGAP1,KDM4C,DDN,TCF4,ZEB1,SSBP2,FLRT2,SPHK2" Drug 1491_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,NDRG2,ADD2,APOC1,CFLAR,SCAPER,GYG2,ARHGAP33,CLGN,CLCN3,QKI,PPP6R2,DMPK,DLC1,KAT8,FHL1,DISC1,GLYR1,GPER1,GPR37,GRB10,RASSF8,MBD1,MEF2C,KITLG,MMP16,ADAM22,NF1,RETREG1,PPARA,FAM184A,RGS12,STUM,TRA2B,PPP4R3A,SPART,SYN2,IQCE,CHST8,TK2,BEX4,KAT6B,KCNAB1,ADAMTSL3,RNF170" Drug 22_DN 1-phenylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,AK2,AMPD3,APBA2,DNAH17,CALB2,CAPN3,CCNT1,P2RX6,CBFA2T2,SCARB1,CNTFR,NCOR1,DPP6,TSPAN5,OPTN,ETV1,FGF1,PCYOX1,FERMT2,PCLO,BTN2A1,PTPRT,FAM107A,RASSF8,ELOVL5,AFF1,MYO7A,NUCB2,PDE1C,NLE1,PRODH,PTCH1,SUSD4,RNASE1,ZFP30,SLC11A1,SNCA,NMNAT2,MYCBP2,TAL1,TBL1X,SLC19A3,UCHL1,LAS1L" Drug 2324_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADORA1,ALCAM,TRMT9B,AMH,BIN1,CDC42BPA,APC,RASL11B,ATP2B2,CFLAR,SGCE,CAMK2B,HIP1R,ARHGAP33,LHX2,CRYM,SNCAIP,RIMS2,SEC14L5,TMCC2,ERCC2,OLFM1,FGFR1,SRCAP,RUNDC3A,STON1,INPP1,LSS,MGAT3,ADAM22,NEFH,MTRF1L,PTPRB,RGS12,GSTCD,SCN2B,SLC2A5,PKNOX2,ZNF423,ZBTB43,PCDHA5,VIPR2,LAT2,KCNK12,KCNAB1" Drug 4760_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASIC1,AMPD3,PPP4R4,PLA2G4C,PDE8B,ATP2B2,SCAPER,CACNA1G,CFAP410,ASIC3,ARHGAP24,SPOCK3,DMPK,EDN1,FAM13A,PLXNC1,RASGRP2,PTK2B,SCARA3,FAM49B,SRCAP,GRIK4,ATXN2L,ICA1,KIT,NTRK2,MAPK7,ELOVL2,RFX2,SH3BGR,ASAP3,PKNOX2,ZNF334,TROVE2,JMJD6,SYP,ZEB1,TRIM2,CRTC1,PARD3,TPM2,VLDLR,SPHK2,SLC17A7,KCNAB1" Drug 3215_DN Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,ASIC1,NDRG3,ADRA1D,AP2A2,LTBP4,AMPD2,BIN1,CAMK2G,TAOK2,EPS15L1,VAX2,HOMER3,WHRN,CTH,GPRASP1,MAML1,DAPK3,EDNRA,FEM1B,EIF4G2,EIF5,RASGRP2,MTSS1L,OGA,BTN2A1,MAP4,TM6SF1,KITLG,NFYA,PALM,PCDH9,RETREG1,STRN3,SAMD9,RGS12,COA1,KDM4B,SPART,TROVE2,ARHGEF9,PLCB1,TK2,PIK3R5,REEP1" Drug 3605_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,LTBP4,BIN1,APAF1,PPFIA3,MARK4,CACNA1I,CALB1,CALB2,CAMK2B,RUNX1T1,WHRN,CSF1,OSBPL3,DBT,ELMO1,FAM13A,PIPOX,AFF2,GFER,ITGAM,KHK,MID1,MSI1,MYT1,NF1,P2RY1,PCDHGC3,C19orf57,ELOVL2,ZMAT4,KLHL11,ASAP3,PKNOX2,LIMCH1,IZUMO4,ARC,HIF3A,GPR161,ICAM5,TPM2,OSBP2,LAT2,KCNK12,SLC30A3" Drug 5681_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADORA2A,APAF1,AZGP1,CFLAR,CHRNA4,AATK,IPCEF1,CNTNAP2,RASSF2,SNAP91,SPOCK3,TENM1,ERCC2,NRN1,FHL1,CSPG5,SIGLEC8,ALDH1L1,GRM8,ATXN2L,KCNH2,MATN3,MMP16,ADAM22,MYT1,NOVA1,NPTX1,NTRK2,P2RY1,LRP12,SEPT4,PTPRD,NKAIN1,RGS12,ZFHX4,ZFP2,LIMS2,MAPKBP1,PEG10,HEY1,R3HDM1,PIK3R5,SLC30A3,SLC30A4,PARP11" Drug 4407_DN Terconazole [67915-31-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "AMPD3,BIN1,AMT,APBB2,SLC4A4,RCBTB2,SOCS6,TAOK2,CNTN1,WHRN,SPOCK2,CNNM1,EGFR,KHDRBS3,GAD1,ALDH1L1,RUNDC3A,TJAP1,IPO5,LMO2,MAN2A2,MAP4,TM6SF1,ADAM22,STRN3,MAPK7,CEP97,C1orf54,RGS12,EMID1,FAM214B,KDM4B,TSNAXIP1,IQSEC2,THSD1,TTBK2,IQCE,PCDHA6,DICER1,CABIN1,HIRA,VGF,SPHK2,EMSY,SLC17A7" Drug 2698_DN "ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "RALGAPA1,NDRG2,AGT,C1QTNF3,TRMT9B,AMT,CDC42BPA,APC,APOC1,RIPK1,MPDZ,NRP2,AKAP7,ARHGAP32,DAPK3,BRINP1,TOM1,PLEKHA1,PTK2B,DLC1,OGA,INPP5K,RUNDC3A,POLL,SPACA9,PADI2,TJAP1,KHK,MEF2C,MYO6,NF1,CNOT4,PDE4A,FSD1,BCAS3,PTCH1,RIPOR1,CCDC92,IZUMO4,SPTAN1,TSPYL2,PLCB1,ADGRL3,THRA,SSBP2" Drug 6506_UP Alfadolone acetate [23930-37-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,ADORA1,AK2,LTBP4,BEGAIN,SEMA7A,BAIAP3,CAMK2G,CBFA2T2,CNN3,PICK1,COL9A3,NECTIN3,VCAN,GREB1,GIT2,RUSC2,RASGRP2,GALC,SIGLEC8,GCNT2,GSTM5,HMGCR,DHX35,KCNN1,ADAM22,MX1,GPR85,NLE1,PTX3,RGS3,GSTCD,FBXW7,KCNIP1,SBF1,ASAP3,PREX2,ZHX3,ARHGAP26,IQCE,TRIM2,ZNF34,SLC44A1,FLRT2,LAT2" Drug 5948_DN rotenone; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,ADRA1B,BEGAIN,GAS7,PPP4R4,PROM1,CHN2,LHX2,CREM,CSF1,PDE4DIP,CNTNAP2,MFAP3L,HIPK3,FCF1,EGFR,EIF5,NRN1,FGF1,SCARA3,SRCAP,TDRKH,CNTRL,KCNN1,KIFC3,MAPT,AFF1,MMP17,P2RY13,OPRL1,CLDN11,PTN,SH3BP2,BTBD7,OGDHL,KIF13A,KDM4B,ZC3H13,ARHGAP26,PCDHGA10,NSD1,TIAM1,R3HDM1,TNS1,OSBP2" Drug 1597_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,CDC42BPA,CDK10,EIF4G3,BACH1,WASF1,CAST,KRIT1,CNOT8,CNTFR,PPP1R16B,CTH,DCAF8,ZNF337,MBNL2,DCTN4,DENND4A,SEC23B,SMC2,ERAP1,IRAK3,KTN1,LAMP2,PIK3R1,RETREG1,PLCD1,LRP12,PPM1B,ATXN7,SCP2,SEC14L1,CCDC88A,FNBP1,UHRF1BP1L,NEK4,KLHL7,TK2,TNS1,HIRA,UBE3A,WIPF1,TRIM9,ZNF142,EPM2A,RNF170" Drug 2845_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SEMA6A,SRPX,APC,ATP6V0A1,KIF1A,CFLAR,SYNJ2,MTMR2,CFAP410,CAMK2G,CLGN,IQCK,RCHY1,DZIP3,PPP6R2,DAPK3,GIT2,MFAP3L,EDNRA,MBNL2,IRAK4,FAM198B,DISC1,INPP5K,SRCAP,POLL,SLC2A6,HNMT,LIG4,SETD4,ZSCAN32,ZSCAN2,CEP97,RXRA,SBF1,ANKRD6,BTBD7,GLT8D1,VPS13A,ARC,EXOC7,SLC44A1,VGF,EPM2A,UBE3B" Drug 7239_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADORA1,AK2,C1QTNF3,APOC1,CDC14B,PRX,MARK4,ST3GAL5,CALB2,CAMK2B,CACNA2D2,ASIC3,EPS15L1,STOML1,AKAP7,CPS1,NCOR2,PDE4DIP,RIPOR2,NRN1,ANKFY1,ALDH1L1,GCNT2,SRCAP,ELOVL5,HNMT,KPNA5,LIG4,KITLG,MITF,MSI1,ADAM22,NNAT,CNOT4,KCNIP1,SYBU,FAM214B,PHLDB1,JMJD6,TACR1,PCDHGA10,TK2,PDIA2,MAP3K12,SENP7" Drug 4102_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ABR,AMH,APC,DNAH17,BACH1,CFLAR,CACNA1A,PLEKHB1,CNTFR,WHRN,AKAP5,ENTPD4,NCOR2,CSF1,RIMS2,MFAP3L,ECM2,CNNM1,ING4,COQ7,ZNF549,ETV1,FGF1,FGFR1,FLT1,TDRKH,TJAP1,IL12A,NNAT,NOVA2,FAM184A,ZMAT4,CCDC102B,RPS20,SNCA,KDM4B,TSNAXIP1,ASTN2,MCF2L,PCDHGA10,CRTC1,TK2,TRIO,LAT2,SEMA3B" Drug 4084_DN Moxonidine [75438-57-2]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASIC1,C1QTNF1,APBB2,PPFIA3,SHROOM2,MARK4,NCOA1,ST3GAL5,BAIAP3,KRIT1,CBFA2T2,TAOK2,CNTFR,WHRN,AKAP5,CDC42BPB,CSF1,SLITRK5,GPRASP1,MFAP3L,COQ7,DENND4A,ZNF549,CDKL3,DLC1,SEMA4D,B4GALNT1,GNAL,TDRKH,GPER1,ICA1,MYT1,NOVA2,GSTCD,RPS20,AMBRA1,PREX2,ARHGEF40,SMARCD3,PCDHGA10,THRA,R3HDM1,KLC2,EVI5,GAN" Drug 1680_UP Panthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "CDC14B,SLC4A4,SYNJ1,CFAP410,RAB28,GPRASP1,JAKMIP2,FBXL5,FGFR1,TXNL4A,GPER1,JAK2,KITLG,NF1,NFYA,PCDH9,CDK18,PLTP,PMP22,PPP2R2B,PPP5C,PRODH,PTPRE,CEP97,FAM184A,GTDC1,EMID1,ASAP3,PREX2,PPP4R3A,SMARCD3,UNC5B,PLCB1,EXOC7,PCDHA6,ZNF34,PARD3,KAT6B,PDIA2,CLDND1,KCNK12,NDRG4,TFIP11,KAT6A,SENP7" Drug 6811_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,AP2A2,C1QTNF1,ALK,PPP4R4,SLC2A11,ALDH7A1,BACH1,SCAPER,SGCE,ARHGEF1,CBFA2T2,COL9A3,ABI3BP,VCAN,CNTNAP2,DCAF4,USP6NL,SNPH,DBN1,RUSC2,BAIAP2,ADAM28,CSDC2,SPACA9,HNMT,ITGAM,MARK1,MIA2,ZNF862,PLCB2,KLHDC8A,FBXW7,TCP11L1,RPS20,CLIP1,ZNF821,SH3GL3,SPART,ARHGEF9,CRTC1,TUBB1,FAM155A,WIPF1,SPHK2" Drug 3692_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "C1QTNF3,AMT,APAF1,SLC4A4,ST3GAL5,SCAPER,MYRF,BAIAP3,CAMK2B,PLEKHB1,CLCN3,PICK1,AKAP7,NCOR2,PHF14,DMPK,CDON,IRAK4,MRNIP,SRCAP,PCDH17,KCNMB4,CACFD1,RASSF8,TJAP1,PIK3R1,CEP41,KCTD17,ASAP3,FNDC3A,PREX2,CCDC88A,RBM34,ZHX3,SPTB,DDN,LHPP,ARC,TK2,R3HDM1,CDK20,RPRM,NT5M,PCBP4,GAN" Drug 4189_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,ADCY6,APOC1,PDE8B,KIF1A,ARHGEF7,CFAP410,SOCS6,CLCN3,NCOR2,CSF1,VCAN,MFAP3L,EXOG,DTNA,MRNIP,F5,FGFR1,ANKFY1,TMEM8B,GRM8,KCNF1,LIFR,PACRG,PDE4D,RETREG1,PPARA,GRAMD1C,BCAS3,PTPRN2,FBXW7,MRAS,FRMPD1,ST6GAL1,ARHGEF40,SPTAN1,CAMTA2,TRIM2,CRTC1,GPR161,VGF,REEP1,ZNF225,KCNAB1,UBE3B" Drug 3413_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "C1QTNF1,SEMA6A,BEGAIN,TRMT9B,BIN1,GAS7,PDE8B,ADAM23,SGCE,HAP1,CLGN,FOXN3,ABI3BP,CSF1,DCAF8,JAKMIP2,PLXNC1,C3orf18,HSD17B14,VPS13B,IGSF6,SCML2,FGFR1,FYN,SRCAP,AHDC1,ITPKA,KCNJ5,LSS,MBD1,MSI1,PLCD1,PTN,RGS3,RGS12,RASA3,SNCA,RBM34,ANKRD12,CRTC1,TK2,PIK3R5,UBE3A,VLDLR,SPHK2" Drug 4497_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,ALK,AMH,GAS7,ATP1A3,CFLAR,GYG2,TAOK2,ARHGAP22,SULT4A1,ABCG1,ERC2,PYGO1,MYEF2,SEMA3D,TNK2,ST3GAL6,GNAO1,GRIK5,CACFD1,FAM107A,ICA1,MARK1,MBP,MT1M,P2RY1,ENPP2,PFKFB2,PFKFB4,STRN3,GDPD2,PTPRH,ZSCAN2,FBXW7,RPS20,SH3BP2,SLC11A1,HECW1,ADGRL3,PCDHGA10,PIK3R5,FLRT2,SPHK2,REEP1,PARP11" Drug 3666_UP Riluzole hydrochloride; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "APC,CDK10,ZSCAN18,ADAM23,NRP2,BMP7,CACNA1I,DLGAP2,CNTNAP2,RIPOR2,MYEF2,MFAP3L,EXOG,RGS17,ELN,CORO2B,FGF12,AGAP2,SEMA4D,GABRB3,SEPT9,ALDH1L1,GNAO1,GPER1,GRIK5,ITGA7,KCNJ5,KIFC3,MARK1,MMP16,NNAT,NRCAM,PALM,PNMA3,RGS4,RNASE1,CNKSR2,PDZRN3,UNC5B,ZC3H13,PLCB1,ADGRL3,PCDHGA10,TNS1,TRIO" Drug 3577_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADGRF5,LTBP4,SEMA7A,APC,CDK13,SYNJ1,SYNJ2,CACNA1I,CFAP410,FOXN3,ASIC3,CNN3,CPS1,ARHGEF10,DBT,HEYL,FGFR1,BAIAP2,FHL1,FOXF2,SIGLEC8,SPACA9,ELOVL5,KCNN1,KIFC3,MMP17,ADAM22,NF1,NTRK2,NTRK3,PLTP,LRRN3,RGS12,TCP11L1,RPS6KA2,SALL1,CNKSR2,SLC2A5,KANSL3,SLC9A5,SNCA,ZNF415,WSCD1,VIPR2,ADAMTSL3" Drug 5106_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "MTUS1,ADAM15,CFLAR,LHX2,QKI,CREM,HAPLN1,DAPK3,EDIL3,FCF1,FAM13A,EGFR,MBNL2,STX2,ETV1,ZNF589,ANKFY1,PDLIM5,CSPG5,GCNT2,GPD2,HSF2,IL6ST,INPP5B,KCNN1,MEF2C,PIK3R1,STRN3,WDR25,ZNF671,SBF1,ZFP30,SLC14A1,ZKSCAN3,SS18,NXT2,DICER1,TMPO,KLC2,ZBTB14,ZNF24,EVI5,MPPE1,PHTF2,SENP7" Drug 5280_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,NDRG2,ADORA2A,AGT,BIN1,CDC42BPA,APC,SEMA4G,MARK4,ADAM15,BCL7A,NRP2,SYNJ2,CFAP410,ARHGEF2,CLGN,PICK1,WHRN,SH2B1,CNTNAP2,TBC1D5,JAKMIP2,MFAP3L,LYPD1,DTNA,EDN1,PIPOX,FER,SRCAP,GPER1,PCLO,GRB10,BTN2A1,KIF5A,LMO2,KITLG,RPS6KA2,SBF1,SNCA,ZHX3,RGL1,TBCEL,TRIM2,ZNF34,WBP2" Drug 6623_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "BIN1,CDC42BPA,APC,DNAH17,ARHGEF2,RAB28,HOMER3,IQCK,CREM,NCOR2,DZIP3,C2CD2L,TMCC2,CDON,RGS17,CDKL3,ETV1,BAIAP2,SEMA4D,FYB1,DISC1,SEPT9,SCIN,IL6ST,MAP4,AFDN,MX1,PFKFB2,PIK3R1,MBOAT7,FA2H,PPARA,WDR25,RIPOR1,ZDHHC14,TCP11L1,RPS6KA2,RXRA,ZNF667,KDM4B,DDN,RPGRIP1L,TIAM1,TNS1,NT5M" Drug 5750_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NDRG2,SPARCL1,LTBP4,BMP7,BMPR1B,CACNA1I,CAMK2B,CBS,PLEKHB1,CNTFR,AATK,SNCAIP,SUSD5,MAML1,MFAP3L,PLPPR4,EDIL3,FGFR1,DENND2A,RUNDC3A,COPS8,KCNJ5,KHK,LAMA2,NF1,NPTX2,NRCAM,NTRK2,PALM,PCDH9,PDE4D,PIK3R1,MINDY2,PPP2R2B,PTN,RET,NEK11,RASA3,SNCA,KDM4B,SYN2,CRTC1,PIK3R5,RPRM,EPM2A" Drug 4150_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "APAF1,APBA2,AQP6,SLC2A11,CFLAR,CNN3,WHRN,AATK,ARHGEF10,DAPK1,EDN1,SRPK3,ERBB2,FGFR3,FHL1,DCTN2,FAM49B,NSG1,OGA,FYB1,FYN,CPLX2,ALDH1L1,POLL,PCLO,SPACA9,KCNN1,KHK,KIF5A,MEF2C,MID1,NTRK2,PDE1C,ELOVL2,PID1,RGS12,GSTCD,EMID1,KDM4B,CDK19,THSD1,SZT2,SLC35G2,SLC17A7,PARP11" Drug 7332_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,AP2A2,AK2,ALCAM,CDC42BPA,APC,APOC1,PPFIA3,CDK13,NUMB,CA12,SPAG9,ZMYM4,RAB28,NCOR1,SOCS5,DZIP3,GPRASP1,LYPD1,IRAK4,COQ7,F8,NOP56,GRB10,RNFT2,KCNF1,LIG4,KITLG,ZNF862,RNASEL,DCUN1D2,GSTCD,NEK11,TCP11L1,UHRF1BP1L,CEP68,SZT2,TMEM121,VAV1,XRCC4,REEP1,TFIP11,EMSY,MARCH8,GAN" Drug 6010_DN Triamterene [396-01-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "AP2A2,ALCAM,AMT,APBA2,APC,ALDH7A1,SYNJ2,SRSF11,ABI3BP,CSF1R,CNTNAP2,FAM169A,KAT8,TRAF3IP2,GAD1,USP19,POLL,TDRKH,GRB10,IL6ST,KIF2A,MMP16,LYRM9,NF1,PRPH,SAMD9,PTN,CEP97,SEC14L1,MRAS,SH3BP2,BTBD7,CXXC4,SNCA,ZHX3,CLASP2,MCF2L,TK2,CDK20,ZFP37,REEP1,GDPD5,SEMA3B,KCNAB1,KAT6A" Drug 5361_DN Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ASPHD1,PPFIA3,NCOA1,LHX2,RAB26,AKAP7,IQCK,ENTPD4,LRIG1,ZNF337,GIT2,LYPD1,CNNM1,ANKMY1,FECH,ZNF274,SEPT9,AHDC1,MSL3,KCNMB4,INPP5B,MBD1,SETD4,OGG1,OPA1,RETREG1,PRODH,PRPH,APTX,PTCH1,GSTCD,FBXW7,ATXN7,FBXO11,SPART,CEP68,ARHGEF9,PDLIM2,TNS2,PARD3,KAT6B,CDK20,METTL3,CLDND1,SMIM8" Drug 5274_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,ADD2,NME5,KSR1,KALRN,SLC16A4,FAM189A2,PICK1,SNCAIP,ARHGEF10,GREB1,RIMS2,TMCC2,DMPK,DTNB,DUSP9,EDNRA,SUGP2,VPS13B,ZNF274,SRCAP,SOX21,KCNJ5,KIT,AFDN,MMP16,NEFM,NELL2,PCBP3,PDE4B,PRKCB,RELN,SNRK,PTCH1,PID1,CCDC40,SEMA6D,ZNF821,SH3BP2,PKNOX2,SNCA,PDZD2,ICAM5,R3HDM1,EVI5" Drug 6815_DN Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "ADCY6,ADRA1D,AP2A2,SEMA6A,BIN1,APBB2,CFLAR,SYNJ2,SCAPER,TAOK2,QKI,SIPA1L1,PDE4DIP,FAM169A,HDAC4,SLC12A6,EDNRA,ING4,TNK2,EZH1,SCML2,KAT8,FGFR1,IQCG,GLYR1,MAPT,TM6SF1,NACA,PCDH9,SLC25A23,FSD1,APTX,SH3BP2,SLC9A5,ZKSCAN3,KDM4B,IQSEC2,PHLDB1,IQCE,TMEM121,CHST8,CDK20,ZBTB14,ZNF45,EMSY" Drug 1510_UP Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "SYN3,MARK4,SYNJ2,CAMK2B,HIP1R,ARHGEF1,ARHGAP33,SOCS6,LHX2,QKI,CNR1,SNCAIP,SPOCK2,MFAP3L,C3orf18,HSD17B14,NRN1,DLC1,FGF12,NEU3,INPP5B,JAK2,ADAM22,CDK18,GPR85,PFKFB2,PPP5C,PRPH,RELN,CNTLN,PTPRB,ZSCAN2,FAM184A,GAL3ST4,KCTD17,CARF,KCNIP1,FRMPD1,PKNOX2,ERC1,TBCEL,HEY1,PIK3R5,CDK20,PLSCR4" Drug 1707_UP Acetohexamide [968-81-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "DOC2A,AMT,APC,PLA2G4C,MARCH3,SLC4A4,SLC2A11,B4GALT6,RAB28,CREM,NCOR1,TBC1D5,GIT2,RCAN1,CNNM1,EGFR,ANKMY1,ZNF589,TMEM8B,GHR,MALT1,GLYR1,SLC2A6,ELOVL5,ZNF862,CNOT4,NPTX1,SETD4,PRKAR1B,PRPH,GSTCD,ZNF331,SUPT20H,PREX2,PPP4R3A,SLC22A4,KDM4C,PLCB1,TRIM2,TPM1,ZKSCAN5,VIPR2,LMF1,SLC30A3,GJC2" Drug 4949_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "NME5,SEMA6A,AMPD3,KCNAB2,FAM131A,SEMA4G,SLC16A4,CLGN,CSF1,CTH,RIMS2,TBC1D5,EGFR,LRRC17,STX2,PTK2B,ZNF589,FGF13,SRCAP,PCDH17,RUNDC3A,GLYR1,ICA1,IL6R,LIG4,ADAM22,RETREG1,PPARA,CEP41,ELOVL2,ZNF493,EMID1,CLIP1,AMBRA1,LIMCH1,KDM4B,PDZD2,ZBTB43,RGL1,PHLDB1,TACC1,PARD3,XRCC4,ZBTB14,GDPD5" Drug 6796_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.30E-06 1.45E-01 1.24E-04 1.40E-03 45 197 "RALGAPA1,LTBP4,CDK10,DNAH17,CFLAR,KSR1,SOCS6,CLOCK,SIPA1L1,GREB1,ARHGEF4,DAPK3,RUSC2,DMPK,DTNA,EDN1,IQCG,PDLIM5,CAMKK2,GPER1,GPR37,JAK2,LIG4,MAN2A2,MMP16,MPP2,TAGLN3,NTRK2,STRN3,PRKAR1B,SNRK,KCTD17,ZFHX4,ASAP3,SMARCC2,ZSWIM8,CDK19,TSPYL2,ATP10B,TROVE2,PLCB1,TACC1,MCF2L,PLPPR2,ZNF24" Drug 7547_UP Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.33E-06 1.46E-01 1.25E-04 1.41E-03 44 191 "EPB41L5,NCOA1,MPDZ,TAOK2,RAB26,CRY2,CTH,GPRASP1,DAPK3,DPH1,TOM1,REEP2,FGFR1,TRMO,FYB1,SRCAP,ITPKA,LIG4,MBD1,LYRM9,NDP,SLC11A2,PALM,PTN,PTPRE,SUGCT,ZNF671,RASA3,ASAP3,LIMS2,MYH15,LIMCH1,DOP1A,DBNDD2,ZBTB43,POGZ,OBSL1,TIAM1,TNS1,TRIO,XRCC4,SPHK2,EMSY,HPS4" Drug 3172_DN Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.33E-06 1.46E-01 1.25E-04 1.41E-03 44 191 "ASPHD1,ABHD6,TRMT9B,CDC42BPA,APC,APOC1,RASL11B,SLC4A4,ATP6V0A1,BCL7A,SYNJ2,ARHGEF6,CRY2,CYBB,GIT2,DTNA,TOM1,EDNRA,FEM1B,CDKL3,ZNF44,TRAF3IP2,GRB10,RNFT2,HNMT,MEIS2,SCAMP5,MSI1,NNAT,SLC11A2,STRN3,POLG,PRKAR1B,RELN,GTDC1,EMID1,ZNF821,ASTN2,DOCK9,SLC44A1,CABIN1,UPF3A,PCBP4,TIGD6" Drug 1659_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.35E-06 1.47E-01 1.25E-04 1.41E-03 41 173 "NME5,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,ARMCX2,JAKMIP2,OPTN,MBNL2,EXTL2,BAIAP2,FYN,CYP46A1,RAB40B,TDRKH,STON1,RNFT2,MXI1,NEK1,PCDH9,SERPINI1,PKIA,PRPH,PTCH1,SH3GL3,PPM1E,WDR47,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,ZNF45,REEP1,SLC17A7" Drug 1637_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.35E-06 1.47E-01 1.26E-04 1.41E-03 43 185 "NME5,ALCAM,MARK4,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,ARHGEF10,PDE4DIP,ARMCX2,TSPAN5,OPTN,FYN,RAB40B,STON1,GPR37,RNFT2,PADI2,MITF,MXI1,NEK1,SERPINI1,PMP22,PKIA,PRPH,PTCH1,SH3BGR,SH3GL3,PPM1E,ASAP3,KDM4B,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,ZNF45,REEP1,SLC17A7" Drug 1891_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A" Broad Institute CMAP Up 3.36E-06 1.47E-01 1.26E-04 1.41E-03 42 179 "ABHD6,ADRB2,MTUS1,AGT,ARNTL,MARK4,ZBTB10,ST3GAL5,HIP1R,CSNK1E,CTH,C2CD2L,FAM13A,MBNL2,TAOK3,BAIAP2,FYN,TDRKH,GUCY1B1,FAM69A,MEF2C,TAGLN3,PCDH9,RETREG1,SMOX,PPM1B,PKIA,PTCH1,RGS4,ASAP3,SLC11A1,KDM4B,FNBP1,THSD1,ELOVL4,CEP68,RGL1,KLHL7,SYT1,HEY1,SSBP2,EVI5" Drug 2830_UP Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.36E-06 1.47E-01 1.26E-04 1.41E-03 42 179 "NDRG2,NME5,ALK,CDC42BPA,APBB2,SLC4A4,CFLAR,GYG2,SGCE,ARHGEF1,RCBTB2,MFAP3L,HIPK3,EGFR,ACSL4,FGFR1,HPCAL4,CAMKK2,SEPT9,TXNL4A,GNG4,SLC2A6,ELOVL5,HMGCR,KCNH2,KHK,LSS,MITF,PCDHGC3,TMOD2,MBOAT7,MINDY2,PTPRD,C1orf54,RPS6KA2,KCNIP1,ASAP3,SPP1,KDM4C,ZNF423,ELOVL4,TRIM2" Drug ctd:D008942 Mitoxantrone CTD 3.47E-06 1.52E-01 1.30E-04 1.46E-03 53 247 "C3orf14,ANK2,KCNAB2,ZSCAN18,BMP7,CACNA1G,CACNA2D2,ABCG2,MAGED1,RCHY1,VCAN,CTH,HDAC4,DAPK1,CHRDL1,DMD,EPB41L2,ERBB2,EXTL2,FDFT1,FHL1,FOXF2,FYN,MTHFD2,GLUL,GUCY1B1,ELOVL5,IDH3A,JAK2,KCNH2,LAMA2,MEST,MXI1,NEFH,PDE4D,ABCB1,SCHIP1,IRX1,PTPRE,RBBP8,SCN2B,CASC3,FNDC3A,SEC31A,BTBD3,MYCBP2,SPP1,SATB2,TRIM2,ZMAT3,TPM1,UCHL1,EVI5" Drug 6358_UP Naproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ASPHD1,PPFIA3,SEMA4G,STX16,SYNJ2,CCNT1,SCARB1,CACNA2D2,ARMC8,SLC4A8,ENTPD4,ABCG1,CSNK1E,PDE4DIP,GPRASP1,MFAP3L,FAM13A,SUGP2,EGFR,EPB41L2,FGF1,FGFR1,SCARA3,CSPG5,ZNF44,SIGLEC8,SRCAP,HNMT,KIFC3,MEIS1,NDP,NPR2,MAPK7,TCP11L1,ELMO2,LIMCH1,SNCA,SOX15,KDM4C,ARHGAP26,THSD1,SS18,NT5M,SEMA3B,SLC17A7" Drug 1466_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SYN3,AK2,TRMT9B,AMPD3,BIN1,APBB2,BCAS1,SLC4A4,ATP6V0A1,CFLAR,ST3GAL5,KALRN,HAP1,CARS,USP2,ARHGEF2,LY86,CRMP1,GPRASP1,DAPK3,HS3ST2,DTNB,EPHB1,ERCC2,DENND4A,DLL3,OGA,IL6R,LMO2,MBD1,NF1,SETD4,PFKFB2,PLCD1,GRAMD1C,ZFP30,MYH15,CDK19,STX1A,EXOC7,RPGRIP1L,TK2,TRIO,HPS4,ST7" Drug 2259_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "AK2,ALCAM,TRMT9B,SEMA7A,APC,AQP6,PRX,ADGRB3,BMPR1B,GYG2,RHBDL1,SLC16A4,CBFA2T2,CDH2,CHN2,CRMP1,DTNB,MBNL2,VPS13B,STX2,APC2,FGFR3,DLL3,OGA,ADAM28,GRM8,GSTM5,TJAP1,KIFC3,PLCB2,LRP12,MINDY2,RELN,SNRK,RFX2,SEMA6D,FRMPD1,ASAP3,ZNF430,SNAP25,ATP10B,ZEB1,CRTC1,SLC17A7,NLRP3" Drug 491_UP dopamine hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,ANK2,APC,GAS7,MTMR3,CREM,ENTPD4,BRINP1,PLEKHA1,HSD17B14,STX2,ZNF589,CAMKK2,GABRG2,DISC1,RUNDC3A,COPS8,ELOVL5,KCNJ5,L1CAM,STMN1,MATK,MPP2,ADAM22,MYO9A,NEK1,NELL2,NNAT,NPY,SETD4,PDCD2,PDE4B,PLXNB1,PTN,PTPRN,SUSD4,ATXN2,CDK5RAP2,CLASP2,PHF24,OBSL1,PCDHA5,ACTR6,TNS1,VIPR2" Drug 5628_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "GAS7,AZGP1,CFAP410,CA8,CACNA2D1,HAP1,CCK,LY86,CNN3,WHRN,DMPK,HIPK3,ERBB4,ERCC2,SPEG,GPR162,ADAM28,PRUNE2,PCLO,SPACA9,GUCY1B1,KIF5A,LRP1B,MEF2C,MMP17,MX1,NEFM,NELL2,NNAT,NPR2,NPTX2,CDK18,PLCD1,PURG,PNMA3,LRRN3,TRIM68,KCNIP1,PKNOX2,KDM4B,TSNAXIP1,SYN2,CUX2,HEY1,UCHL1" Drug 1512_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "RALGAPA1,ASIC1,LTBP4,APBA2,PPP4R4,SYNJ1,ST3GAL5,CAMK2B,RUNX1T1,ARHGEF2,ARHGAP33,TAOK2,QKI,WHRN,CSF1R,GREB1,BRINP1,MBNL2,C3orf18,FHL1,FOXF2,HPGDS,MSL3,IL6ST,ITGAM,MAP4,MMP16,NPR2,NPTX2,PAX6,PCDH9,CDK18,PDE4A,PNMA3,SEPT4,MINDY2,PRPH,STUM,BTBD7,STX1A,DOCK9,TK2,TNS1,TRIO,KAT6A" Drug 6762_UP Cefotiam hydrochloride; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,ADRA1D,AP2A2,C1QTNF3,BEGAIN,AMT,PPP4R4,SLC4A4,CFAP410,TAOK2,FAM131B,PLPPR4,DTNA,DUSP9,FGF1,LILRB4,PRUNE2,KCNB1,TM6SF1,LYRM9,NF1,NTRK2,PCDH9,PFKFB2,RETREG1,POU6F1,PPP5C,GDPD2,PTH1R,KLHL11,RASA3,FBXO11,PREX2,SLC11A1,HECW1,COBL,TAL1,PCDHGA10,TK2,HIRA,TFIP11,EMSY,KCNAB1,EPM2A,DPF3" Drug 7138_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "MTUS1,C1QTNF1,BIN1,APBB2,CDK13,BMP7,ARHGEF7,KYAT1,SCARB1,ARHGEF2,LHX2,HOMER3,CREM,SPOCK3,HIPK3,ING4,TRMO,CINP,TMEM8B,MSL3,CNTRL,GUCY1B1,RASSF8,SYNPO,INPP5B,SCAMP5,ZNF862,NF1,NPR2,PLCD1,MINDY2,MAPK7,PRPH,PTN,DZIP1,PEX26,FAM214B,SNCA,DOP1A,PDLIM2,DOCK9,CRTC1,ZBTB14,ZNF711,MPPE1" Drug 2165_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,APAF1,EPB41L5,CDK10,MTMR2,CAMK2B,CAST,CD86,STOML1,PICK1,CREM,SH2B1,AATK,PPP6R2,ZFYVE16,DBN1,SV2B,MBNL2,EIF1,LRRC17,BAIAP2,PDLIM5,CAMKK2,GALC,INPP5K,ALDH1L1,SRCAP,ADAM28,GSN,ATXN2L,KHK,MAP4,MBNL1,ZNF862,PDE4A,WDR25,SBF1,STUM,SPTB,SPART,TBCEL,LMF1,VSNL1,SPHK2,TIGD6" Drug 5690_UP Droperidol [548-73-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SYN3,ASIC1,BEGAIN,DOC2A,CDC42BPA,APBA2,AQP6,SLC4A4,PROM1,KALRN,RUNX1T1,CDH2,NRXN3,CNTFR,PDE4DIP,EGFR,MRNIP,SCARA3,OGA,CHL1,GABRG2,SRCAP,RAB30,TOX3,GRIK5,GRM8,SOX21,SHISAL1,KHK,NELL2,NOVA2,P2RY1,PDE1C,PFKFB2,PLCD1,PLXNB1,LRP12,RASGRF1,FRMPD1,SLA,KANSL3,MYH15,ZNF415,SAMSN1,THRA" Drug 7375_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NME5,DDO,SHROOM2,CFLAR,HIP1R,CBFA2T2,PLEKHB1,CRY2,CSF1,CSF1R,DPH1,EDNRB,PLXNC1,ZNF589,FGF1,ANKFY1,CGREF1,FYN,GFER,GLYR1,LPAR4,GRIK5,TJAP1,LMO2,TAGLN3,CLDN11,GDPD2,PTPRN2,GSTCD,RPS6KA2,ASAP3,SNCA,DOK5,RBM26,DIP2A,PHLDB1,JMJD6,NSD1,GPR161,R3HDM1,CABIN1,TRIO,AMACR,REEP1,DPF3" Drug 4326_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "AQP6,CDK10,ADAM15,ST3GAL5,CFAP410,ARHGEF2,LARGE1,MYRIP,ABCG1,SUSD5,CYBB,SV2B,PLXNC1,OLFM1,FOXF2,PRELID3A,ADAM28,GPER1,PADI2,HLF,LMO2,LSS,MSI1,PALM,CCDC40,ENOX1,ZNF821,MRAS,SH3BP2,ASAP3,HKDC1,PKNOX2,SLC11A1,ZBTB43,RBM26,ARC,MCF2L,CRTC1,GPR161,AMACR,TRO,XRCC4,NT5M,KCNAB1,EPM2A" Drug 5818_UP Hecogenin [467-55-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "BRAP,APBB2,APC,LGR5,SEMA4G,ARHGDIG,MARK4,SLC4A4,CALB2,HAP1,CNOT8,VCAN,DCAF8,BRINP1,GIT2,ARMCX2,MYEF2,C2CD2L,SCML2,ZNF589,DENND2A,SEPT9,GRIK5,GRM8,AP4S1,MAPT,TAGLN3,CNOT4,NTRK2,BCAS3,PTPN13,PTPRN2,PID1,TCP11L1,KCNIP1,FNDC3A,OGDHL,KDM4B,IQSEC2,IQCE,TRIM2,RIMBP2,VGF,TFIP11,RNF170" Drug 1538_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA1,SRPX,BEGAIN,AMPH,APOC1,MARK4,MTMR3,GYG2,CFAP410,CDO1,ASIC3,STOML1,QKI,HOMER3,ABI3BP,CRMP1,CSF1,DCAF4,DOCK4,BRINP1,ARMCX2,SPEG,DLC1,MSL3,ADAMTS13,IL6ST,KCNH2,MAN2A2,ADAM22,CDK18,PPARA,MAPK7,PTN,EMID1,BTBD7,COA1,OGDHL,LIMCH1,TTBK2,TRIM2,CRTC1,TK2,HIRA,WIPF1,EPM2A" Drug 6748_UP Bisoprolol fumarate; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "MTUS1,OGT,PKP4,EPB41L5,MTMR3,RUNX1T1,FOXN3,SH2B1,CSF1R,CNTNAP2,FAM131B,MFAP3L,C2CD2L,HIPK3,COQ7,NRN1,ST3GAL6,FGFR3,IQCG,GATM,ALDH1L1,GNAL,ADAMTS6,ELOVL5,KCNF1,ADAM22,MX1,NF1,ENPP2,RETREG1,PSD,TMEM231,ZFP30,ZNF334,IQSEC2,CEP68,SYT5,TAL1,PCDHGA10,VSNL1,MKRN3,SPHK2,EMSY,KCNAB1,EPM2A" Drug 7506_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NDRG2,AMH,CDC42BPA,APC,SLC4A4,N4BP2L1,CFLAR,ASIC3,SH2B1,PDE4DIP,JAKMIP2,DTNA,DTNB,HIPK3,PHF20L1,MBNL2,HSD17B14,SPEG,ZNF589,FECH,FER,FGFR1,SCARA3,GALC,SEPT9,MALT1,MSL3,ITPKA,JAK2,L1CAM,MIA2,MMP16,ADAM22,PPP5C,MAPK7,CARF,TCP11L1,ATXN2,TTC17,IZUMO4,TRIM2,SSBP2,ZKSCAN5,ZNF45,GAN" Drug 6041_DN Evoxine [522-11-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "MTUS1,ARHGDIG,CFLAR,CAMK2G,KYAT1,SCARB1,SRSF11,PLEKHB1,LHX2,BAG4,CREM,CRY2,PDE4DIP,DZIP3,MFAP3L,LYPD1,DMTF1,DTNA,TOM1,MRNIP,ANKMY1,GALC,TXNL4A,COPS8,DHX35,KCNF1,LIG4,MPP2,OPA1,RETREG1,PTCH1,C1orf109,ROBO1,FBXO11,SLC22A4,ZKSCAN3,TMCC1,SPART,THSD1,ELOVL4,NSFL1C,ANKRD12,EXOC7,ZNF34,MPPE1" Drug 2463_DN "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NDRG2,MTUS1,C1QTNF3,BIN1,MAP4K3,APC,APOC1,ARRB1,NCOA1,BACH1,FOXN3,IQCK,CSNK1E,TSPAN5,HIPK3,EIF1,NCALD,IQCG,FYB1,RAB40B,SMAD1,ZNF862,NEK1,NFYA,SLC11A2,PIK3R1,PTPRN2,ZDHHC14,RNASEL,CARF,ZNF821,FAM102A,AMBRA1,PPP4R3A,SIRT2,SS18,KIAA1107,DICER1,TMPO,TRPS1,UBTF,MAP3K12,PHTF2,TIGD6,SENP7" Drug 7508_DN CP-863187 [668981-07-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NDRG2,OGT,APC,SLC4A4,N4BP2L1,SYNJ2,CA4,ARHGEF1,CRLF1,VAX2,QKI,IQCK,SH2B1,GIT2,MFAP3L,DTNA,DTNB,HIPK3,FEM1B,EIF5,SPEG,FER,SCARA3,PDLIM5,FAM49B,SEPT9,ARFIP1,HNMT,ITPKA,L1CAM,MMP16,ADAM22,NF1,CCSER2,MAPK7,ZCWPW1,SBF1,ASAP3,IZUMO4,IQSEC2,CDK20,SSBP2,HIRA,ZBTB14,GAN" Drug 4286_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SYN3,ALK,AMPD3,PKP4,APOC1,ZSCAN18,SLC2A11,N4BP2L1,ADAM23,RUNX1T1,CBS,LDB2,SLC16A4,CD86,CNR1,AKAP5,CSF1,CSNK1E,VCAN,RIMS2,SHANK1,FCF1,STX2,ZNF549,ETV1,ST3GAL6,ZNF44,HPGDS,GRM2,KCNF1,KCNQ3,MMP16,ADAM22,MSR1,MYO7A,MYT1,NNAT,CDK18,PIK3R1,PPARA,ZFP2,FRMPD1,ZC3H13,NFASC,OSBP2" Drug 1640_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "AK2,LTBP4,CDC14B,CDK10,BMP7,MTMR2,ABCG1,LRIG1,PDE4DIP,DCAF8,C2CD2L,PARD6A,DNM1,F8,FGFR3,GPR37,IL6ST,INPP5B,ITPKB,KHK,MAP4,SCAMP5,GIT1,SLC11A2,SETD4,MBOAT7,RIPOR1,NKAIN1,CEP97,SBF1,SGK1,FUZ,ABLIM3,BTBD7,SPTAN1,TROVE2,CAMTA2,CEP68,VPS13A,EXOC7,KIAA0930,SIK3,KAT6B,TPM1,ZBTB38" Drug 6255_UP Spironolactone [52-01-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA2A,ADGRF5,CDC42BPA,APC,CDK13,PDE8B,NCOA1,CFLAR,CAMK2G,ARHGEF2,CSF1,PDE4DIP,CTH,JAKMIP2,MFAP3L,DTNA,MBNL2,VPS26C,F5,POLL,IL6R,MAP4,AFDN,MYCN,NF1,SLC11A2,PLTP,LRP12,POLG,PPP2R2B,FBXW7,RPS6KA2,ANKRD6,SLC11A1,SLC22A4,ZNF423,SPTAN1,TSPYL2,SYN2,EXOC7,NSD1,PCDHA5,PLPPR2,WIPF1,KCNAB1" Drug 3976_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "FZD9,ADGRF5,AMT,ANK2,GAS7,CACNA1I,CACNA1G,CAMK2B,RUNX1T1,VCAN,RIPOR2,SPOCK2,DMD,EDN3,AASS,FGFR1,RUNDC3A,POLL,GNAO1,SOX21,HLF,TJAP1,ADAM22,NTRK2,PDE4B,PDE1B,PPP1R1A,MAPK7,DCHS2,GDPD2,KHDRBS2,TRIM68,NUDT11,PKNOX2,FAIM2,HECW1,PHLDB1,PCDHGA10,DOCK9,HIF3A,PIK3R5,AMACR,UBE3A,ZNF711,MKRN3" Drug 1423_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,APBA2,APOC1,ARRB2,ATP2B2,CAMK2G,ARHGEF2,CREM,CRMP1,ZNF337,SPOCK2,DCTN1,FEM1B,APH1A,ZMYND10,KAT8,FGFR1,PRKAG2,FOLR2,GAA,B4GALNT1,RUNDC3A,TDRKH,BTN2A1,MAN1B1,KIF5A,OCRL,OGG1,RETREG1,PLCB2,PTN,CCDC25,PCMTD2,KCNIP1,FAM102A,EPN2,ELMO2,MAPKBP1,FNBP1,ZC4H2,ZMAT3,CA14,HIRA,ZNF74,REEP1" Drug 2983_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "RALGAPA1,ADD2,ADORA1,OGT,BMP7,QKI,CNN3,SLC4A8,NCOR2,ABCG1,SNPH,MFAP3L,KLHL3,HIPK3,CNNM1,ING4,FGFR3,ATXN2L,KIFC3,MYCN,TREM2,PFKFB4,PLCL1,MAPK10,PTPN13,PTPRG,RFX2,NUDT11,NEK11,PREX2,SLC11A1,SNCA,DOP1A,IZUMO4,PEG10,CDK19,ARC,TK2,TRPS1,SSBP2,UGT8,VSNL1,ZNF225,KCNAB1,ADAMTSL3" Drug 2436_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "C3orf14,BEGAIN,PPFIA3,PRX,KIF1A,ADGRB1,CACNA1I,HIP1R,COL9A3,ABI3BP,NCOR2,PDE4DIP,DAPK3,MFAP3L,SEZ6L2,MRNIP,ELN,EIF1,FLNC,FYB1,SIGLEC8,NEU3,POLL,TDRKH,GUCY1B1,MSI1,ADAM22,PCDH9,PFKFB4,DUSP26,SEPT4,RELN,TMEM104,PTPN13,RFX2,PKNOX2,ZC3H13,ARC,SYT5,TK2,UGT8,VSNL1,CLIP2,SLC17A7,ADAMTSL3" Drug 3307_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA1,APBA2,CDC14B,RASL11B,NRP2,CFLAR,ARHGEF7,TAOK2,WHRN,DMPK,DTNA,SUGP2,PLXNC1,ING4,STX2,SPEG,ZNF589,FGFR1,FHL1,AGAP2,OGA,DISC1,SEPT9,PRUNE2,IL6ST,MEF2C,MID1,ADAM22,MX1,CLDN11,RGS12,KCNIP1,CPEB3,CXXC4,ZBTB43,SAMSN1,SS18,ST5,KIAA1107,TBCEL,PCDHGA10,VIPR2,DNALI1,EVI5,DPF3" Drug 4594_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADGRF5,C1QTNF3,APC,DNAH17,PTCH2,ADAM23,KSR1,BMPR1B,FUBP1,MTMR3,CACNA1G,RUNX1T1,SCARB1,SOCS6,RAB33A,ABCG2,CREM,PLPPR4,HIPK3,ING4,ZNF549,ETV1,FGFR1,GNG4,GRIK5,GRM8,HLF,IL6ST,JAK2,KCNF1,LIG4,NPTX1,P2RX7,PDE4D,MINDY2,PPP2R2B,FBXW7,ARHGEF40,KDM4C,SLC44A1,TLR4,REEP1,NT5M,KCNAB1,RNF146" Drug 2279_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADRB2,APC,SLC2A11,N4BP2L1,BAIAP3,CBFA2T2,CDO1,WHRN,CABP1,CRMP1,DMPK,CDON,MBNL2,EIF4G2,TENM1,VPS13B,RASGRP2,MTSS1L,EPHB1,STX2,ERBB2,DLL3,OGA,FYN,SEPT9,GPER1,TJAP1,KCNJ5,MBP,PCBP3,PFKFB2,MINDY2,SAMD9,PTPRN2,CCDC40,ENOX1,SLC2A5,ZHX3,THSD1,PHLDB1,TNS1,TPM2,TUBB1,ADAMTS9,SLC17A7" Drug 3326_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SYN3,AGT,NME5,KIAA1324,APAF1,GAS7,LDLRAD4,CALB1,USP2,TAOK2,NECTIN3,NCOR2,SPOCK2,EDIL3,VPS13B,F5,FAM198B,AGAP2,GAD1,ERAP1,ALDH1L1,RUNDC3A,GNAO1,KCNQ3,MEF2C,KITLG,NEK1,PDE4B,LRP12,RFX2,ZFHX4,KLHDC8A,GSTCD,SEMA6D,ASAP3,KANSL3,ARHGEF40,SLC9A5,SNCA,ARHGAP26,SPTB,TBCEL,UGT8,WIPF1,ITM2C" Drug 5002_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ASIC1,AGT,APBB2,GAS7,BCAS1,RGS20,MARK4,CFLAR,SCAPER,GYG2,CACNA1I,CFAP410,CACNB4,TAOK2,CRY2,SIPA1L1,TMCC2,ECM2,HIPK3,HSD17B14,VPS13B,STX2,NRN1,KAT8,OGA,GAD1,GLYR1,GPR37,NXPH3,MID1,MMP16,OCRL,PPP5C,PRKAR1B,MAPK7,GTDC1,CCDC88A,ZC3H13,ATP10B,DMXL2,PARD3,SLC30A3,SEMA3B,KCNAB1,PHTF2" Drug 7471_UP Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ABR,ADORA1,SYT13,SLC4A4,FOXN3,PICK1,NCOR2,CSF1,PDE4DIP,DAPK3,EGR3,MRNIP,ENO2,ACSL4,DLC1,SYT17,RAB30,ADAMTS13,RNFT2,PADI2,TJAP1,JAK2,MAP4,AFF1,ADAM22,MYT1,PCDHGC3,PDE1C,PLXNB1,MBOAT7,LRRN3,CEP41,NKAIN1,KHDRBS2,TCP11L1,RPS6KA2,KDM4C,STX1A,ZNF34,CDK20,FAM155A,REEP1,TFIP11,SEMA3B,PHTF2" Drug 6384_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA2A,SYT13,CDC42BPA,APC,AKAP7,CTH,FAM131B,SHANK1,ERCC2,IGSF6,PTK2B,FGF1,BAIAP2,SCARA3,AGAP2,FUT9,POLL,GNAL,GRIK5,SYNPO,HNMT,ICA1,L1CAM,LIG4,MGAT3,AFDN,MMP16,ADAM22,CLDN11,PAX6,MTRF1L,RELN,ZSCAN2,ZNF493,TCP11L1,SATB1,ZNF423,SUPT5H,ARC,SYNE1,PIK3R5,TRO,WIPF1,SPHK2,PLSCR4" Drug 4706_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ABHD6,NDRG2,ADGRB3,NRP2,LY86,BAG4,CSF1,RGS6,RIMS2,GIT2,DBT,EIF4G2,RRAGB,FGF12,FGFR1,AFF2,LYVE1,HPGDS,GLYR1,LIG4,SMAD1,MBD1,MID1,NOVA2,P2RY1,CDK18,SERPINI1,LRP12,PPP5C,PRODH,RASGRF1,NLGN1,SNCA,TAL1,DMXL2,PCDHGB6,PCDHA6,DICER1,TNS1,CDK20,UBE3A,WIPF1,NT5M,SLC17A7,JPH3" Drug 3973_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "C1QTNF1,SEMA6A,BEGAIN,PDE8B,ADAM23,KSR1,GYG2,LHX2,TPP1,WHRN,SNCAIP,DNAH9,EDNRA,HIPK3,PTK2B,FGFR1,GPR75,SPACA9,NXPH3,IRF8,NPTX2,NTRK2,PCDH8,POU6F1,CEP41,MASP1,RFX2,STUM,ST6GAL1,CNKSR2,ZNF334,SNAP25,PDZD2,NMNAT2,LMO3,PHLDB1,TACR1,TCF4,DOCK9,OBSL1,ICAM5,CHST5,PDIA2,DPF3,AP3B2" Drug 3710_UP Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ALK,BEGAIN,ANK2,LGR5,PDE8B,ATP2B2,BMP7,BAIAP3,KALRN,HAP1,CD86,ARHGEF2,CHGB,TAOK2,SULT4A1,CNTFR,MYRIP,CRYM,DAPK1,MFAP3L,HS3ST2,EDN3,APC2,AGAP2,FYB1,SIGLEC8,ALDH1L1,GNAL,GNAO1,IRAK3,IRF8,KCNB1,ADAM22,CLDN11,P2RX7,PGAM2,PRODH,NKAIN1,RGS4,SEMA6D,RASA3,TUBB1,KCNAB1,FAM13C,NLRP3" Drug 4546_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADCY6,ADRA1D,APBB2,TPP1,SLITRK5,ARMCX2,PLPPR4,EXOG,DTNA,EDNRA,CNNM1,PLXNC1,EIF5,ANKMY1,F8,FGFR1,BAIAP2,DENND2A,GAD1,GUCY1B1,TJAP1,MIA2,GIT1,MX1,NDP,CNOT4,MAPK3,MAPK7,RIPOR1,RAD51D,SH3TC2,MAPK12,ATXN2,FBXO11,DZIP1,SLC22A4,DOCK9,TNS2,CRTC1,UGT8,LMF1,WIPF1,TFIP11,HPS4,SMIM8" Drug 4265_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SEMA6A,BBOX1,SYT13,PPP4R4,ATP2B2,SYNJ2,CACNA1G,KCNAB3,NRXN3,CNTFR,COL9A3,CSF1,C2CD2L,DRP2,EDN3,PIPOX,FAM198B,CORO2B,FGFR3,AFF2,EFCAB2,FYB1,GFER,HPGDS,TOX3,GPD1,PRUNE2,GRM8,ATXN2L,IL6R,KCNF1,MAN2A2,ADAM11,ADAM22,NEFM,NF1,NPTX1,NTRK3,PCSK5,RASGRF1,FRMPD1,RIMBP2,TRO,XRCC4,DNALI1" Drug 3128_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA1,AGT,OSBPL1A,BEGAIN,CDC14B,CACNA1I,CACNB4,CAPN3,SLC16A4,EPS15L1,BRINP1,DTNA,ING4,STX2,RRAGB,KAT8,FGFR1,FYB1,ALDH1L1,SRCAP,ZNF276,PCLO,GUCY1B1,PADI2,ICA1,MAP4,PLCL1,FSD1,PKIA,RELN,ZSCAN32,KCTD17,PNMA8A,MAP6D1,MRAS,BTBD7,ZNF667,KDM4B,SPART,TROVE2,OBSL1,TRPS1,FLRT2,TFIP11,PCBP4" Drug 7274_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "MTUS1,BIN1,KCNAB2,CDC14B,SYNJ2,SCARB1,NRXN3,HAPLN1,CSF1,SNPH,B3GAT3,FBXL5,RUSC2,SPOCK3,PLXNC1,ST3GAL6,TRMO,FYB1,SEPT9,GPR75,MSL3,CACFD1,GUCY1A1,SHISAL1,FAM69A,PLCD1,PPARA,MAPK7,PTPRN2,DCUN1D2,TRAPPC13,MAPK12,PPP4R3A,OGDHL,RBM34,KDM4B,TSNAXIP1,THSD1,SS18,JMJD6,PARD3,CABIN1,KCNAB1,EPM2A,KAT6A" Drug 5868_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "DDO,ARRB2,SLC4A4,CFLAR,ST3GAL5,MYRF,CACNA1A,SCARB1,PLEKHB1,CRY2,GPRASP1,EDN1,HIPK3,SEMA3D,CELSR3,ETV1,ZNF589,FER,OLFM1,ANKFY1,PDLIM5,FYB1,SPACA9,GRIK5,DHX35,IGF1,ITGA7,KCNF1,KCNJ5,KHK,KPNA5,CNOT4,NPY,ZSCAN2,TRAPPC13,MAPK12,SLC8A1,ELMO2,SNCA,PDZRN3,VAV1,WIPF1,SLC17A7,UBE3B,GAN" Drug 4023_DN Metronidazole [443-48-1]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA2A,LGR5,PDE8B,ARHGEF7,CACNA1A,NRXN3,HOMER3,CRMP1,AATK,CSF1,CNTNAP2,RUSC2,SGSM2,DMPK,CNNM1,MRNIP,ETV1,FCGRT,AFF2,GCNT2,GFER,POLL,TDRKH,GRM8,ICA1,SHISAL1,ITPKA,GIT1,CNOT4,PTN,ATXN7,ANKRD6,FAM214B,SMARCD3,IFT122,SPTB,DDN,ARC,DOCK9,NSD1,TIMP4,RPRM,NT5M,EVI5,KAT6A" Drug 3756_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADRA1D,AMPD3,CDC14B,BMP7,SYNJ1,CBFA2T2,TAOK2,RAB28,ENTPD4,PDE4DIP,SLITRK5,DTNA,SUGP2,DCTN2,SEPT9,GFER,POLL,PRRC2B,INPP5B,ITPKA,JAK2,MT1M,NF1,MAPK7,WDR25,SUSD4,ZNF671,MCMBP,ATXN7,SUPT20H,SH3BP2,FNDC3A,DZIP1,DHX30,ELMO2,OGDHL,IFT122,SNCA,ATP10B,SYT1,TIAM1,LAT2,VPS35L,KAT6A,TIGD6" Drug 2772_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NDRG2,AP2A2,SEMA6A,OGT,APC,APLP1,CDK13,BACH1,ST3GAL5,BAIAP3,CACNA2D1,CNTN1,ABCG1,CSF1R,CSNK1E,PHF14,BRINP1,TMCC2,HIPK3,EIF4G2,EIF5,ING4,SPEG,FECH,JAK2,LIG4,MAP4,MID1,SLC25A23,MINDY2,MSANTD2,CLIP1,PKNOX2,SLC22A4,ARHGAP26,TROVE2,TRIM2,CRTC1,CHST8,SLC44A1,TRIO,LAT2,ZNF45,MARCH8,PHTF2" Drug 3769_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "MTUS1,ALK,AMPD3,APBB2,APC,FAM131A,SLC4A4,ADGRB2,ARHGEF1,CRMP1,DZIP3,DCAF4,EXOG,IRAK4,DCTN2,CGREF1,DISC1,IL12A,NF1,NFIX,CNOT4,PDE1C,STRN3,POLG,PRPH,ACSS3,C1orf54,SUSD4,ATXN7,ASAP3,SLC4A3,ZHX3,ARHGAP26,IQSEC2,ATP10B,SS18,SYN2,KIAA1107,ZEB1,SSBP2,HIRA,VLDLR,XRCC4,DPF3,RNF146" Drug 2715_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,AP2A2,ALK,BEGAIN,BIN1,CDC42BPA,PRX,BMP7,SGCE,CFAP410,CACNA2D1,CDO1,ABCG2,QKI,CRY2,AATK,DAPK3,DBT,KLHL3,SV2B,EXOG,DUSP9,PLXNC1,OLFM1,FGFR1,AFF2,PRELID3A,CPLX2,NXPH3,ICA1,IL12A,KIFC3,NEFM,OPRL1,PDE4D,PLCD1,PPP2R2B,CEP41,VPS13C,PTPRN2,MAP6D1,RPS20,PHLDB1,SPHK2,FZD3" Drug 6104_DN Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADORA1,AP2A2,TRMT9B,AMPD3,AMPH,PDE8B,CFLAR,CA4,CACNA1A,ARHGEF1,CBFA2T2,ARHGAP33,RCBTB2,NRG2,CRY2,PDE4DIP,ARMCX2,MFAP3L,IRAK4,ING4,ERCC2,CDKL3,F5,DLC1,FHL1,SEMA4D,SRCAP,PRRC2B,RASSF8,MAP4,MID1,MPP2,NECAB2,MAPK7,GRAMD1C,PRPH,ZSCAN32,RASA3,SH3BP2,SMARCD3,KDM4B,ST5,STX1A,TBCEL,EMSY" Drug 6388_DN Orlistat; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ASPHD1,ADD2,BIN1,APBA2,APC,BMP7,HAP1,CAMK2B,RAB26,CRMP1,PDE4DIP,SEC14L5,GPRASP1,ECM2,TNK2,GCNT2,SRCAP,GHR,GPD2,BACH2,IFI16,LMO2,MEF2C,MT1M,LYRM9,PGAM2,MAPK10,CNNM2,PTPRD,ZFP30,FBXO11,SLA,PEX26,EPN2,CCDC88A,TSNAXIP1,KDM4C,KIAA0930,OBSL1,GPR161,BEX4,TPM1,CDK20,SPHK2,HPS4" Drug 4165_UP Trimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SYN3,LTBP4,BEGAIN,BIN1,KSR1,CALB1,CDH2,AKAP7,NCOR2,DBT,CDON,FRY,MTSS1L,SPEG,PTK2B,CAMKK2,OGA,FYB1,CPLX2,GNAO1,PRUNE2,MCHR1,GRM8,LAMA2,ADAM11,MID1,TAGLN3,PCDHGC3,PFKFB2,PLTP,PTCH1,ELOVL2,RGS4,RGS12,ST6GAL1,ZNF334,SNCA,FAIM2,PHLDB1,TCF4,TNS1,UBE3A,UGT8,LAT2,XRCC4" Drug 4489_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "SEMA7A,APAF1,APBB2,APC,BCAS1,CDK13,ATP6V0A1,CFLAR,FUBP1,STOML1,HOMER3,AKAP6,NCOR2,ABCG1,SEC14L5,CHRDL1,EXOG,EGFR,COQ7,ZNF391,SCML2,ST3GAL6,SPACA9,PADI2,KCNJ5,MSR1,NTRK2,NTRK3,PDE1C,PFKFB2,STRN3,MINDY2,PTCH1,ZSCAN32,PTPRD,C1orf54,RET,TCP11L1,FBXO11,PKNOX2,PLCB1,TACR1,MCF2L,SPHK2,KCNAB1" Drug 6707_UP Propofol [2078-54-8]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ADD2,APC,PPP4R4,ATP6V0A1,ADAM23,BMP7,IL33,THSD7A,ARHGAP22,SULT4A1,CRMP1,CRY2,RGS6,SLITRK5,MYEF2,MFAP3L,EDN3,RASGRP2,IGSF6,FGFR3,CHL1,ERAP1,GPR75,IGF1,IL6R,KCNJ5,KCNQ3,NF1,PTPRB,RGS3,SEMA6D,FRMPD1,FBXO11,DZIP1,ZNF334,SNCA,ZSWIM8,SPTB,COBL,TACR1,GPR161,TLR4,TNS1,CHST5,REEP1" Drug 6073_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "BEGAIN,BIN1,CDC42BPA,SEMA7A,PLA2G4C,N4BP2L1,BAIAP3,ARHGAP33,SULT4A1,HAPLN1,CNTNAP2,SEC14L5,HDAC9,DOCK2,CNNM1,LRRC17,EPHB1,FGFR3,HPGDS,LPAR4,KCNJ5,AFF1,AFDN,TAGLN3,MYO7A,P2RY13,CNOT4,NOVA1,CDK18,SERPINI1,LRP12,PPP5C,MAPK7,ZNF493,ZMAT4,TRIM68,KLHDC8A,SLC9A5,ZNF415,UNC5B,CRTC1,TIMP4,UBE3A,WIPF1,MKRN3" Drug 7359_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "ASIC1,ABHD6,ALCAM,AMPD3,APBA2,PLA2G4C,NUMB,CFLAR,ST3GAL5,LRRFIP1,PLAA,BAG4,CREM,PDE4DIP,RIMS2,PPP6R2,GIT2,DBT,DTNA,HSD17B14,FGFR1,TRAF3IP2,MSL3,GRB10,KCNF1,KCNH2,NPR2,PDE4A,POLG,MINDY2,PRKAR1B,NEK11,ATXN2,ZFP30,PPP4R3A,EPN2,COA1,DIP2A,SZT2,PCDHA6,TMEM121,TRIO,VIPR2,MAP3K12,DNALI1" Drug 5334_UP Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "APC,BCAS1,MARK4,ST3GAL5,MTMR2,HOMER3,CTH,GREB1,HDAC4,KIAA0586,TMCC2,E2F5,ZNF589,FGF12,ANKFY1,SRCAP,TXNL4A,GLYR1,GRB10,ELOVL5,HSF2,IL6ST,ZNF862,NEK1,NPR2,PRKAR1B,RAD51D,FAM184A,SBF1,SYBU,ANKRD6,EPN2,BTBD7,SMARCC2,TTC17,THSD1,VPS13A,ARC,SATB2,TRIM2,AP4E1,ZNF34,TIAM1,XRCC4,ST7" Drug 6395_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.80E-06 1.67E-01 1.36E-04 1.53E-03 45 198 "NME5,BIN1,APAF1,APC,APLP1,SPTBN4,MTMR3,LDLRAD4,CLDN10,FOXN3,LY86,PICK1,DGKG,DAPK3,RUSC2,PTK2B,AGAP2,KHDRBS3,GAD1,SRCAP,GFER,GLYR1,GNG4,PRUNE2,GPR37,KCNH2,MAP2,MMP16,MYT1,NTRK3,LRP12,PRKAR1B,MAPK7,FAT4,RFX2,ASAP3,SNCA,DOP1A,PCDHGA10,GPR161,SLC44A1,TK2,PDIA2,ADAMTS9,KCNAB1" Drug 5667_UP Metyrapone [54-36-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.85E-06 1.69E-01 1.37E-04 1.55E-03 44 192 "NDRG2,ADORA2A,AMPD3,PRX,MARK4,CACNA1I,CA4,DLGAP1,RAB33A,COL9A3,MYRIP,CSF1,HDAC9,ING4,MRNIP,RCAN2,CORO2B,FHL1,FAM49B,NSG1,OGA,TMEM8B,SEPT9,NEU3,SESN1,ADAM28,PCLO,SYNPO,IFI16,IGF1,ADAM22,NF1,NTRK3,PLCD1,EMID1,RASA3,PKNOX2,MAPKBP1,SNCA,STX1A,R3HDM1,EMSY,SEMA3B,SLC17A7" Drug 6044_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.85E-06 1.69E-01 1.37E-04 1.55E-03 44 192 "ABHD6,ALCAM,NCOA1,CFLAR,CBFA2T2,SEPT7,FOXN3,SLIT2,ARMC8,RCHY1,AKAP12,CSF1R,FAM169A,RASSF2,JAKMIP2,DTNA,HIPK3,COQ7,TAOK3,FGFR3,SYNCRIP,STAU2,SRCAP,GLYR1,TDRKH,GRB10,GRIK5,INPP1,MPP2,RETREG1,SBF1,ZNF821,SH3BP2,TTC17,CLASP2,PHLDB1,PLCB1,TACC1,TMEM121,ZNF34,TK2,BEX4,PARD3,ZIC1" Drug ctd:D003010 Clorgyline CTD 3.88E-06 1.70E-01 1.38E-04 1.56E-03 40 168 "ADRB2,APC,ZBTB10,DST,CLGN,PHF14,ZFYVE16,MBNL2,NSRP1,PPP1R1B,POLK,RGPD5,ZNF638,KTN1,LIG4,CHIC1,MIA2,MYO6,NFE2L2,CNTN3,PIK3C2A,SAMD9,VPS13C,ZNF493,REV3L,CLIP1,CCDC112,CHD9,PREX2,BDP1,VPS13A,ANKRD12,STXBP4,TBC1D15,RICTOR,TCEAL7,ZNF138,FZD3,KLHDC1,SENP7" Drug 7499_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.89E-06 1.70E-01 1.38E-04 1.56E-03 43 186 "ASPHD1,KCNAB2,APLP1,PPFIA3,BMP7,ST3GAL5,BAIAP3,CLGN,PDE4DIP,JAKMIP2,OPTN,EIF5,CDKL3,BAIAP2,FYN,CYP46A1,RAB40B,STON1,RNFT2,SLC2A6,MPP2,NEK1,PCDH9,CDK18,PDE4A,SERPINI1,PRPH,PTCH1,RPS6KA2,SH3GL3,ASAP3,SYBU,SLC6A8,ZBTB43,ELOVL4,RGL1,STXBP1,TACC1,HEY1,RUNDC3B,CLIP2,SLC30A3,SLC17A7" Drug 5231_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.90E-06 1.71E-01 1.39E-04 1.56E-03 41 174 "NME5,MARK4,ST3GAL5,BAIAP3,SLC16A4,CLGN,AKAP12,PDE4DIP,ARMCX2,FAM13A,MBNL2,BAIAP2,HPCAL4,FYN,CYP46A1,STON1,GRB10,MXI1,NEK1,PCDH9,ENPP2,SERPINI1,GRAMD1C,PRPH,RADX,SH3GL3,WDR47,FAM214B,PKNOX2,SPTAN1,ELOVL4,RGL1,STXBP1,HEY1,NPL,RUNDC3B,SSBP2,SLC30A3,SLC17A7,ITM2C,PLSCR4" Drug 3787_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.91E-06 1.71E-01 1.39E-04 1.56E-03 42 180 "ABHD6,ADRB2,ARNTL,ST3GAL5,GYG2,USP2,SYNGR3,WHRN,ABCG1,LRIG1,PDE4DIP,CTH,C2CD2L,PLPPR4,RGS17,PTK2B,TAOK3,BAIAP2,FYN,STON1,KCNH2,LIFR,MAPT,MMP16,TAGLN3,PCDH9,ENPP2,SERPINI1,RETREG1,RGS4,THSD1,ELOVL4,CEP68,RGL1,SYT1,COBL,OBSL1,RUNDC3B,SSBP2,TRIM9,SLC30A3,PLSCR4" Drug 5462_UP Piracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "RALGAPA1,FZD9,ADORA2A,C1QTNF1,ALK,SEMA7A,PPP4R4,ARHGDIG,CFLAR,HAP1,RUNX1T1,CHN2,CNTN1,AKAP7,COL9A3,CSF1R,VCAN,HDAC4,JAKMIP2,C2CD2L,MED12,PLXNC1,C3orf18,CORO2B,FGFR1,BAIAP2,INPP5K,GNAO1,HNMT,KCNN2,NTRK2,ENPP2,LRP12,TMEM231,RGS12,ANKRD6,SLC11A1,SNCA,DOK5,SPTAN1,RGL1,KIAA0930,CLDND1,KCNK12,MPPE1" Drug 6093_DN Butamben [94-25-7]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AMT,APBB2,APOC1,PPFIA3,ARHGDIG,PDE8B,ADAM23,CFLAR,SYNJ2,PLEKHB1,VAX2,PICK1,CSF1R,LRIG1,PDE4DIP,CNTNAP2,MFAP3L,RUSC2,TMCC2,ING4,MRNIP,C3orf18,FER,FGF12,ALDH1L1,INPP5B,KCNF1,LMO2,MSI1,NPR2,PDPK1,PLXNB1,MBOAT7,PRKAR1B,MAPK7,PRPH,ELOVL2,SEMA6D,TTBK2,PLCB1,SYN2,PCDHA5,TIAM1,TPM1,ZNF45" Drug 2495_UP Ethionamide [536-33-4]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "RALGAPA1,SYN3,SPARCL1,ALK,AMPH,PKP4,ATP6V0A1,KIF1A,GYG2,HIP1R,CDO1,CHRNA4,ARHGEF10,DZIP3,ARHGEF4,PLPPR4,DTNB,EDNRA,HIPK3,RASGRP2,ZNF549,AGAP2,KHDRBS3,DLL3,SIGLEC8,LILRA2,PCLO,GSN,AP4S1,KIFC3,LAMA2,TAGLN3,NF1,NRCAM,GPR173,RFX2,IZUMO4,PHLDB1,TRO,FAM155A,LMF1,SPHK2,REEP1,KCNAB1,KAT6A" Drug 3202_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AMPD3,APLP1,CDK13,ATP2B2,ADAM23,BACH1,PROM1,KSR1,BAIAP3,ARHGAP33,B4GALT6,CNR1,CPS1,TMCC2,DTNA,DUSP9,PLXNC1,ACSL4,NSG1,TDRKH,GRM8,IGF1,JAK2,KCNN1,MARK1,MITF,MYO7A,NTRK3,CLDN11,PAX6,PFKFB2,PPP5C,ZFHX4,TCP11L1,ZFP2,FAM214B,SLC11A1,SPTB,DDN,SSTR2,ARC,SYT5,OBSL1,PIK3R5,VGF" Drug 644_DN colchicine; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "RALGAPA1,CDC42BPA,PPFIA3,ARHGDIG,NCOA1,SLC4A4,RIPK1,CFLAR,BAIAP3,HAP1,ARHGAP33,HS3ST2,OPTN,SRPK3,TUBD1,GLYR1,DIDO1,GRIK5,PRDM5,SCIN,KCNN1,STMN1,GIT1,NPR2,NTRK3,PPP3CA,PRKAR1B,MAPK3,MAPK10,RNASE1,FBXO11,TSNAXIP1,ZC3H13,ZBTB43,SPART,ST5,DIP2A,SLC19A3,TMEM121,ZMAT3,TNS1,UBE3A,WIPF1,XRCC4,FXR1" Drug 3608_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "NDRG2,AK2,AMT,PPP4R4,ATP6V0A1,SYNJ2,CA12,CAMK2B,CLGN,AKAP7,RCHY1,CTH,GREB1,DBT,MFAP3L,DTNA,SUGP2,ENO2,ZNF589,FGFR3,SEMA4D,EFCAB2,PRELID3A,CGREF1,INPP5K,GPD2,ELOVL5,IL6ST,JAK2,MAPT,KITLG,NF1,CNOT4,NTRK2,PLCD1,PPP5C,TMEM104,MSANTD2,RGS3,BTBD7,SPTAN1,VPS13A,TBCEL,ZKSCAN5,LMF1" Drug 2572_DN Ergocryptine-alpha [511-09-1]; Down 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SYT13,APBB2,SEMA4G,PDE8B,SLC4A4,CACNA1I,HIP1R,FAM149A,NR1D2,CDON,EDNRB,CELSR3,PCOLCE2,ELN,RASGRP2,KAT8,FHL1,ZNF44,SEPT9,SRCAP,CRCP,MSL3,LILRA2,NCKAP1L,MID1,AFDN,MYO7A,MAPK7,MASP1,RIPOR1,FAM184A,MRAS,SH3BP2,FAM102A,FRMPD1,CNKSR2,IQSEC2,DDN,SS18,DMXL2,TNS2,CRTC1,CHST8,TPM1,LMF1" Drug 6974_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ASPHD1,NME5,C1QTNF1,FAM131A,MTMR2,C5,RAB29,BAIAP3,CAMK2B,CAMK2G,RAB33A,SGSM2,DTNA,OPTN,EIF5,ENO2,COQ7,RRAGB,FAM198B,ACSL4,ZNF589,ALDH1L1,MALT1,POLL,CACFD1,MAPT,TAGLN3,NPTX1,PDPK1,MTRF1L,MAPK7,RELN,NKAIN1,GTDC1,RGS12,ROBO1,SEC14L1,TROVE2,ELOVL4,STX1A,PLCB1,TACC1,TPM1,AMACR,LMF1" Drug 1373_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SEMA6A,SLC4A4,AZGP1,ADGRB2,CA12,CACNA1A,CALB2,CACNA2D2,CHN2,CNTFR,PCYT1B,SH2B1,CRMP1,TMCC2,TNK2,SRPK3,ELN,PIPOX,FCGRT,FGFR1,GNAO1,GNG4,SPACA9,CACFD1,GRIN2C,GSTM5,AP4S1,TJAP1,KCNF1,MBP,GIT1,SAMD14,DUSP26,PPARA,PPP5C,PTH1R,PTN,RNASE1,LGI2,LIMS2,SLC6A11,PHLDB1,DNAH7,VGF,VIPR2" Drug 3822_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "NDRG2,APAF1,APBB2,APC,CDK13,ADGRB2,NRP2,IL33,HAP1,CD86,FOXN3,NCOR2,ABCG1,CTH,MAML1,DTNB,EDIL3,EPHB1,ZNF391,GABRB3,SRCAP,GFER,GLYR1,POLL,GRM2,SOX21,PADI2,KCNN2,ADAM11,NPTX2,NTRK3,PNMA3,GDPD2,PTPRN2,RGS12,SH3BP2,KIF16B,SNAP25,SP4,HECW1,IQSEC2,ZBTB43,DOCK9,HIF3A,FLRT2" Drug 6586_DN prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ACTN1,BRAP,CDC14B,ADGRB2,CFLAR,KSR1,SYNJ2,CFAP410,KALRN,B4GALT6,CNTN1,NRG2,ARMCX2,KAT8,BAIAP2,POMT1,GLYR1,MSL3,GNG4,GPER1,CNTRL,CACFD1,TAGLN3,CDK18,POU6F1,PRPH,TMEM104,PTX3,SH3TC2,ZCWPW1,CCDC25,PEX26,CCDC88A,ZNF415,KDM4B,DOP1A,FNBP1,PBLD,THSD1,TRIM2,SZT2,TNS1,SSBP2,RPRM,TFIP11" Drug 4338_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ALK,PPP4R4,BMPR1B,SULT4A1,SNCAIP,IPCEF1,CNTNAP2,CYBB,MYEF2,TENM1,REEP2,BAIAP2,FOXF2,PDLIM5,RUNDC3A,GRIK5,GRM2,GRM8,SOX21,IRF8,KCNB1,NOVA2,NPTX2,NTRK2,PIK3R1,NECAB2,PPP2R2B,VPS13C,PTPRE,RET,FAM214B,PKNOX2,CXXC4,ZSWIM8,SPP1,IQSEC2,NFASC,ATP10B,PLCB1,MCF2L,CRTC1,SLC44A1,CA14,LAT2,NT5M" Drug 5094_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "NDRG2,EPB41L5,APOC1,PDE8B,DNAH17,N4BP2L1,NRP2,FOXN3,RAB33A,IPCEF1,SPOCK2,C2CD2L,TOM1,HIPK3,AASS,COQ7,NRN1,FGFR1,DISC1,SEPT9,LPAR4,GRIK5,BACH2,ICA1,TJAP1,AFF1,CNOT4,PDE4D,PFKFB4,PTPRN2,TMEM231,FAT4,RPS6KA2,CPEB3,ST6GAL1,SLC2A5,KDM4C,ZBTB43,DDN,LMO3,OBSL1,TMEM121,FAM13C,ST7,GAN" Drug 7318_DN Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "MTUS1,CDC42BPA,APBB2,PPFIA3,CDK10,EIF4G3,RIPK1,CFLAR,ARHGEF7,IL33,CHN2,AKAP7,CSNK1E,VCAN,DZIP3,USP6NL,FBXL5,FCF1,MBNL2,ZNF589,TRMO,SEPT9,COPS8,MSL3,HNMT,SHISAL1,ITPKB,TAGLN3,MX1,NEK1,SMOX,SAMD9,RGS4,FBXW7,SLC22A4,LIMCH1,ARHGAP26,IQCE,ZNF34,SSBP2,NDRG4,SH3GLB2,MAP3K12,PCBP4,FZD3" Drug 1482_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SPARCL1,CDC42BPA,SLC4A4,CACNA1I,BAIAP3,LDLRAD4,CALB1,SOCS6,CRMP1,VCAN,RIMS2,DCAF4,GPRASP1,EDNRB,EIF4G2,MTSS1L,NCALD,FGFR1,IQCG,OGA,SEPT9,CPLX2,GLYR1,GRB10,GRIK5,TJAP1,KCNH2,KIT,MBD1,MGAT3,NOVA2,MINDY2,PRKAR1B,SNRK,ZSCAN32,ZSCAN2,TCP11L1,ZNF821,MRAS,ASAP3,CNKSR2,SPART,PLCB1,ARC,EPM2A" Drug 6815_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SYN3,AP2A2,C1QTNF1,BEGAIN,BIN1,ADGRB3,CACNA1I,ARHGAP33,CLGN,NECTIN3,CSF1R,SPOCK2,DTNA,EDNRA,MBNL2,C3orf18,VPS13B,ERCC2,FGFR3,AFF2,FAM49B,TPK1,GPD2,HNMT,IL6R,ITGAM,KPNA5,MIA2,ADAM22,MX1,ZNF862,NDP,NPTX1,LRP12,PRKCB,ASAP3,PPP4R3A,FAM214B,LIMCH1,PLCB1,AGTPBP1,DMXL2,TNS1,OSBP2,NT5M" Drug 7202_UP Glibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ADD1,ALK,APOC1,SPTBN4,PLA2G4C,MARK4,ATP2B2,KSR1,LDLRAD4,KALRN,CBFA2T2,ARHGEF2,ARHGAP33,STOML1,LY86,CNTFR,NCOR2,ARHGEF10,CNTNAP2,TM9SF4,SPOCK3,HS3ST2,RCAN1,DTNA,EDNRA,PLXNC1,FGFR3,ANKFY1,FYB1,ITPKB,KCNH2,MAP4,MSI1,PRKAR1B,MAPK7,SNCA,KDM4C,PHLDB1,TRIM2,CHST8,ZNF34,THRA,AMACR,DNALI1,RNF170" Drug 4140_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AMPD3,APBA2,MARK4,CA4,STOML1,ABI3BP,ARHGEF10,PDE4DIP,CNTNAP2,GREB1,HS3ST2,DUSP9,MBNL2,FHL1,AFF2,FAM49B,ARFIP1,ADAM28,GPD2,PRUNE2,ADAMTS13,GRM8,IL6ST,JAK2,KCNH2,MAP4,KITLG,ADAM22,TAGLN3,NEK1,NELL2,NNAT,CNNM2,ZMAT4,SEMA6D,SLA,CCDC88A,COA1,SNCA,ZC3H13,TBCEL,SMG6,PCDHGB6,XRCC4,SLC17A7" Drug 337_DN felodipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ASIC1,KDM5D,BRAP,CDK13,MTMR2,CACNA1I,RUNX1T1,AATK,ARHGEF10,OSBPL3,PDE4DIP,GREB1,FEM1B,VPS13B,RCAN2,ZMYND10,FGFR1,FOLR2,KHDRBS3,ZNF44,NEU3,ZNF276,HPGDS,NXPH3,KCNQ3,MATK,MBD1,MN1,MYO6,MYO7A,NNAT,PLXNB1,TMEM231,C1orf54,SATB1,FERMT1,KBTBD4,THSD1,ZC4H2,PCDHA5,CHST8,CDH22,TUBB1,LMF1,MPPE1" Drug 3668_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "RALGAPA1,ADRA1D,SCAPER,BAIAP3,HAP1,AP4M1,SEPT7,LARGE1,PLEKHB1,PLAA,QKI,PICK1,SH2B1,DAPK3,DMPK,SUGP2,VPS26C,OGA,FYN,DENND2A,ZNF276,CACFD1,SHISAL1,INPP5B,SCAMP5,PPP3CC,PTPRN2,RIPOR1,CCDC40,GAL3ST4,NEK11,ZFP30,ASAP3,FUZ,SLC4A3,ELMO2,SMARCD3,SPTAN1,SPTB,SS18,ASTN2,CDK20,TPM2,LMF1,ZNF32" Drug 6459_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ABHD6,NDRG2,ADORA1,BIN1,PPFIA3,ATP2B2,ALDH7A1,GYG2,LDLRAD4,DLGAP1,TPP1,STOML1,ARHGEF6,WHRN,COL9A3,AATK,PDE4DIP,CNTNAP2,DCAF4,SPOCK2,EIF5,AGAP2,SIGLEC8,INPP5K,PCDH17,HAS2,HLF,ICA1,IFI16,KCNJ5,MBD1,MID1,CNOT4,PRKAR1B,ELOVL2,RPS6KA2,S100B,PPP4R3A,PDZD2,IZUMO4,WSCD1,TLR4,LAT2,ZNF711,PHTF2" Drug 2526_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ALK,BIN1,AQP6,SYNJ1,CA8,CBFA2T2,CHN2,STOML1,CNTN1,NRG2,SIPA1L1,HS3ST2,DTNB,E2F5,HEYL,ING4,TNK2,HSD17B14,NCALD,PDLIM5,ERAP1,INPP5K,GCNT2,GNG4,GRIK5,GRM8,IGF1,MPP2,PDE4A,MTRF1L,KLK6,PTPRN2,TCP11L1,MAP6D1,SEC14L1,RASA3,PEX26,DOK5,PEG10,SPTAN1,ATP10B,TBCEL,TEK,CHST5,VSNL1" Drug 4677_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "MTUS1,FAM131A,ATP1A3,SLC4A4,CACNA1G,SYNGR3,CRLF1,ABCG2,AKAP7,SLC4A8,ENTPD4,AATK,DAPK3,BRINP1,SPOCK3,EDNRA,PLXNC1,ING4,CDKL3,FYB1,ZNF44,GLI2,MEF2C,AFF1,NF1,NPR2,PDE4D,STRN3,CNNM2,SAMD9,WDR25,ZSCAN2,TMEM231,MCMBP,ZFP30,FRMPD1,SNCA,SOX15,LHPP,THRA,TK2,BHLHB9,WIPF1,NT5M,EVI5" Drug 2095_UP Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "MTUS1,RASL11B,BAIAP3,RAB28,CRY2,SLITRK5,ARHGAP24,PLPPR4,SPOCK3,FCF1,TENM1,RGS17,STX2,ANKMY1,B4GALNT1,SEPT9,GLI2,PRUNE2,LPAR4,KCNB1,TAGLN3,FA2H,TMEM104,GAL3ST4,RGS3,ATXN7,ZFP30,AMBRA1,OGDHL,ZHX3,LHPP,SUPT5H,MCF2L,PHF24,CHST8,TK2,TPM1,TRIO,UCHL1,LMF1,KCNK12,SPHK2,NT5M,EVI5,DPF3" Drug 6713_UP Monobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "MTUS1,PKP4,APC,AQP6,ATP1A3,ATP2B2,ADAM23,CACNA1I,IL33,CA12,CACNA1A,MTMR7,CHRNA4,RAB33A,CSF1,PDE4DIP,DAPK3,SPOCK2,BRINP1,MFAP3L,DMD,EDN3,PLXNC1,CALCRL,EPB41,NRN1,FAM198B,SEMA4D,NSG1,PCDH17,MYH3,NF1,CNOT4,ACSM5,CRTAC1,TCP11L1,EMID1,ZNF821,ZFP30,FBXO11,ARHGEF40,SPTB,PLSCR4,NLRP3,GAN" Drug 4087_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AMH,KCNAB2,CDK10,PPP4R4,NRP2,SYNJ1,CBFA2T2,FOXN3,RAB26,AKAP7,AKAP5,ARHGAP24,DAPK3,MFAP3L,IRAK4,MTSS1L,ZNF549,ETV1,FGF1,IQCG,FLT1,FYB1,ATXN2L,ICA1,IL6ST,MEF2C,AFF1,PDE1C,GPR85,PIK3R1,ZSCAN32,PTPRH,ZSCAN2,BEND5,ZMAT4,RGS12,FBXW7,RPS20,CEP68,PCDHA5,GPR161,TK2,CABIN1,NT5M,GAN" Drug 2635_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ASIC1,ADORA1,ADORA2A,LTBP4,MARK4,RASL11B,ATP1A3,SLC4A4,SLC2A11,N4BP2L1,ADAM23,SCAPER,MTMR3,CFAP410,CA4,ARHGEF1,ARHGAP33,SOCS6,SLIT2,AKAP7,WHRN,LRIG1,PDE4DIP,SPOCK3,MTSS1L,NCALD,ZNF589,IQCG,TRAF3IP2,HAS2,IL6R,INPP5B,MSI1,NTRK2,ENPP2,RETREG1,SAMD9,STUM,SLC2A5,SLC6A8,SPTAN1,IQSEC2,CLSTN2,CUX2,OBSL1" Drug 2652_UP Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ADD2,ADORA1,AP2A2,AGT,SEMA4G,GYG2,CA4,ARHGAP33,TAOK2,ABI3BP,RASSF2,EDNRB,FRY,PLXNC1,EIF4G2,ACSL4,PTK2B,ZNF589,FGFR1,SCARA3,IQCG,SEMA4D,ALDH1L1,GCNT2,GFER,MUM1,ICA1,KCNJ5,ADAM22,SAMD14,PLEC,PLTP,PPP5C,CCDC40,ZNF493,RGS12,SLC11A1,LIMCH1,ARHGAP26,IQSEC2,SPART,JMJD6,PLCB1,SYNE1,SENP7" Drug 7226_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "APBA2,ARRB1,FUBP1,SOCS6,ARMC8,ARHGEF4,EDN1,MBNL2,RASGRP2,EZH1,FAM198B,FGFR3,ALDH1L1,GFER,GLYR1,POLL,GNAO1,PRUNE2,LILRA2,STON1,GRIK5,HLF,KITLG,AFF1,MSI1,P2RY1,NLE1,PPARA,RELN,BEND5,MRAS,CNKSR2,CXXC4,SYN2,WSCD1,RPGRIP1L,PCDHA6,TNS1,TRIO,ZKSCAN5,TUBB1,FAM155A,UBE3A,GDPD5,RNF170" Drug 6885_DN AH23848 hemicalcium salt hydrate; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ASPHD1,SEMA7A,APBB2,CFAP410,CBFA2T2,ABCG1,FAM131B,RIPOR2,ZFYVE16,DAPK3,MFAP3L,AASS,ING4,STX2,FGF1,FGFR1,B4GALNT1,TMEM8B,COPS8,GLI2,SHISAL1,TJAP1,KCNJ5,NFYA,PLEC,C19orf57,PRKAR1B,MAPK7,CNNM2,RPS6KA2,RXRA,SBF1,ZNF821,IFT122,SNCA,TROVE2,SYN2,KIAA1107,TNS1,SSBP2,VGF,XRCC4,REEP1,SLC30A4,MAP3K12" Drug 5906_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AP2A2,AMPD3,APBB2,APOC1,MARK4,HAP1,SEPT7,LHX2,SULT4A1,CNTN1,RIMS2,RASSF2,DAPK3,ING4,RASGRP2,MTSS1L,FCGRT,FGF13,AGAP2,CPLX2,AHDC1,SHISAL1,TJAP1,KCNH2,LAMA2,MID1,ZNF862,CNOT4,NOVA1,MAPK7,SAMD9,ENOX1,RFX2,PNMA8A,CXXC4,NMNAT2,ZC3H13,ATP10B,SAMSN1,PHLDB1,DOCK9,HEY1,OSBP2,SLC17A7,EPM2A" Drug 6403_DN valdecoxib; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ASIC1,C1QTNF3,TRMT9B,APBB2,GAS7,ATP1A3,ADAM23,ADGRB2,BTK,BAIAP3,CA4,CACNA1A,CAMK2B,CBFA2T2,CREM,CSF1R,VCAN,RIMS2,EDNRA,ERCC2,SCML2,PDLIM5,SRCAP,CSDC2,PRUNE2,GRM2,GUCY1B1,HNMT,ICA1,IFI16,INPP5B,KCNN1,ADAM22,PURG,PPARA,PRKAR1B,RELN,ZDHHC14,RPS6KA2,CCDC88A,DMXL2,ZEB1,PCDHA5,SLC35G2,TRO" Drug 1727_DN Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ACADM,ADRB2,SLC25A14,FOXN3,MAP4K4,RNF14,SOCS5,CTH,RUBCN,ZFYVE16,SPOCK2,DBN1,SPATA2,DCTN1,DMTF1,EGR3,KCTD3,ING4,EPB41L2,OGA,KTN1,MBD1,NACA,SETD4,OPA1,STRN3,LRP12,VPS13C,C12orf49,SLC11A1,UNC5B,ZBTB43,SPART,ZNF302,SS18,STAU1,RGL1,DIP2A,AGTPBP1,WBP2,SSBP2,VIPR2,WRN,ZNF184,ST7" Drug 5687_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SYT13,DDO,CDC14B,SPTBN4,N4BP2L1,ADAM23,NRP2,KSR1,CALB2,CD86,CHRNA4,CSF1,DOCK2,EGR3,COQ7,RASGRP2,CORO2B,FGFR1,AGAP2,SRCAP,CSDC2,TDRKH,GSN,IRAK3,INPP5B,MYT1,PALM,PDE4D,VPS13C,KCNIP1,FRMPD1,ASAP3,FNDC3A,LIMCH1,SOX11,ZSWIM8,HECW1,SYT5,TRIM2,TEK,CHST5,UBE3A,LAMP5,SLC30A3,SEMA3B" Drug 4230_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ADORA1,DDO,ARSE,ATP2B2,RGS9,CACNA1G,KALRN,ENTPD2,VAX2,CNTFR,AKAP6,COL9A3,PDE4DIP,CNTNAP2,DMD,EPHB1,ZNF549,PTK2B,FGF12,AFF2,EFCAB2,GABRA3,SIGLEC8,GFER,PRUNE2,GRM8,ATXN2L,SMAD1,MAP2,AFDN,NTRK2,PCDH8,NECAB2,DCHS2,MASP1,KHDRBS2,ZFP2,SNCA,ZNF415,SP2,SYT5,MCF2L,KLHL4,RIMBP2,TUBB1" Drug 5869_DN Pyrilamine maleate [59-33-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ABHD6,AK2,AMT,APLP1,APOC1,MARK4,CLCN3,NRG2,CSF1,ZNF337,KLHL3,EIF5,ING4,TNK2,MRNIP,ETV1,ANKMY1,ZNF589,FGF13,SEMA4D,PRRC2B,GPER1,BTN2A1,RNFT2,SYNPO,ITPKB,IPO5,MBD1,MIA2,TAGLN3,CCSER2,LRP12,SUPT20H,ZNF430,TMCC1,SPATA7,TROVE2,IQCE,SLC35G2,CBX5,HIRA,UBTF,EMSY,PLSCR4,AAAS" Drug 7467_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "AP2A2,ARRB1,MARK4,ALDH7A1,CFLAR,MTMR3,CAMK2G,KYAT1,SOCS6,FAM149A,RCHY1,SEC14L5,EXOG,EDIL3,PHF20L1,ELN,STX2,BAIAP2,B4GALNT1,ERAP1,RAB30,CACFD1,DHX35,TJAP1,MAP4,NELL2,PCDH9,PFKFB2,PLCD1,PLTP,PPP5C,ZSCAN32,GSTCD,ASAP3,SLC11A1,CXXC4,ZC3H13,SYT5,TMEM121,SLC44A1,BHLHB9,PARD3,CDK20,ZKSCAN5,SEMA3B" Drug 6752_UP Pipemidic acid [51940-44-4]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "RALGAPA1,EPB41L5,GAS7,PPP4R4,CDK13,SLC4A4,ST3GAL5,SCARB1,DLGAP1,EPS15L1,ABCG1,RIMS2,SPOCK2,MFAP3L,SV2B,TENM1,F5,CORO2B,PDLIM5,ALDH1L1,SRCAP,GNAL,GSTM5,SHISAL1,TM6SF1,ADAM22,NTRK2,PALM,NLE1,DCHS2,ENOX1,RFX2,PKNOX2,SLC9A5,KDM4C,PLCB1,SYN2,COBL,TAL1,TBCEL,DOCK9,BHLHB9,HIRA,TFIP11,DPF3" Drug 7366_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "NME5,AMT,CDC42BPA,KCNAB2,EPB41L5,SHROOM2,MARK4,CFLAR,KALRN,CACNA2D2,FOXN3,PLEKHB1,WHRN,SLC4A8,PARD6A,CHRDL1,DPH1,CNNM1,FAM13A,EGFR,MBNL2,DENND4A,ETV1,FYN,GLYR1,FAM69A,PRKAR1B,TMEM104,PTCH1,PTH1R,RAD51D,FAM184A,FBXW7,CLIP1,FBXO11,DZIP1,SMARCC2,TSNAXIP1,ZHX3,DDN,CRTC1,ZKSCAN5,KCNAB1,UBE3B,KAT6A" Drug 6308_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "MTUS1,BIN1,PPFIA3,CFLAR,SCAPER,PPP6R2,GPRASP1,ARHGAP24,GIT2,C2CD2L,DYNC1I1,ERCC2,CGREF1,INPP5K,GSN,BACH2,SYNPO,MN1,ZNF862,NDP,NPR2,OGG1,NLE1,PLCD1,FSD1,PPP3CC,PRPH,CNNM2,ELOVL2,SH3TC2,FAT4,PEX26,ELMO2,UNC5B,SS18,ELOVL4,PLCB1,SYT1,EXOC7,TRIM2,MAP3K12,GDPD5,NAV3,URM1,PHTF2" Drug 2744_DN Dipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "APC,FAM131A,APOC1,PPFIA3,ARHGDIG,SLC4A4,BCL7A,SCAPER,GYG2,SCARB1,B4GALT6,FAM189A2,SIPA1L1,MFAP3L,PARD6A,HIPK3,KAT8,BAIAP2,FAM49B,OGA,SEPT9,ALDH1L1,GLYR1,MSL3,KCNH2,MMP16,ADAM22,NPR2,PRPH,ZCWPW1,RIC8B,SH3BP2,FNDC3A,EPN2,BTBD7,ZHX3,ELOVL4,STX1A,PLCB1,EXOC7,PCDHA6,RUNDC3B,HIRA,KCNK12,PHTF2" Drug 167_UP amitriptyline hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "BEGAIN,CDC42BPA,SEMA7A,APAF1,APBB2,BMP7,ST3GAL5,CAMK2A,RUNX1T1,TBRG4,CHN2,CNTN1,CPS1,HS3ST2,DRP2,OPTN,VPS26C,BAIAP2,FHL1,NEU3,PCDH17,RUNDC3A,CNTRL,BTN2A1,IL6ST,ITGAM,MBD1,NELL2,PMP22,PRKCB,PTPRD,RBBP6,RGS3,SEMA6D,PREX2,PKNOX2,ZKSCAN3,ZHX3,SP2,ZC3H13,CDK19,CLSTN2,ST5,RGL1,R3HDM1" Drug 2822_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "APBA2,KCNAB2,PPFIA3,PDE8B,RASL11B,STX16,SLC2A11,KRIT1,RCBTB2,B4GALT6,RAB28,RCHY1,NCOR2,USP6NL,RASSF2,SGSM2,DTNA,HSD17B14,ZNF589,OGA,ERAP1,GCNT2,TDRKH,GRM8,ADAM22,NF1,TREM2,CDK18,CCSER2,PLCD1,LRP12,PPP3CC,RPS20,AP1AR,RASA3,EPN2,THSD1,SZT2,PCDHGA10,CABIN1,HIRA,PLPPR2,VLDLR,EMSY,HPS4" Drug 3216_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "PRX,PTCH2,SLC4A4,ALDH7A1,HAP1,CAMK2G,RUNX1T1,MTMR7,CBFA2T2,NRG2,CNTNAP2,RIMS2,CYBB,HIPK3,ZNF589,OLFM1,FGF12,IQCG,DCTN2,DISC1,RUNDC3A,GNAL,ITPKB,MIA2,AFDN,MX1,ZNF862,NPTX1,GPR85,MAPK7,ELOVL2,ACSM5,RNASE1,CCDC102B,RPS6KA2,ST6GAL1,ANKRD6,EPN2,LIMS2,ZNF334,SYNE1,AP4E1,HIRA,LAT2,KCNK12" Drug 5986_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "GAS7,APOC1,RGS20,DGKI,QKI,NECTIN3,CRY2,DCAF4,DMPK,HIPK3,EBI3,PLXNC1,TNK2,DENND4A,PRELID3A,FYB1,GALC,ALDH1L1,PCLO,GRIK5,GSN,KCNN1,LSS,MAPT,MSI1,NNAT,NTRK2,GRAMD1C,ZSCAN32,PTX3,ZSCAN2,C1orf54,KHDRBS2,ZDHHC14,ZNF821,SH3BP2,PPP4R3A,SLC11A1,TSNAXIP1,ZNF423,CLSTN2,DOCK9,VGF,NT5M,DNALI1" Drug 1521_UP Cyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "SYN3,APOC1,CDC14B,DNAH17,MARK4,KIF1A,AZGP1,CFLAR,SYNJ2,CACNA1I,CCK,ARHGEF2,RCBTB2,CSF1,DCAF4,DOCK4,DNAH9,HSD17B14,BAIAP2,DISC1,GFER,RUNDC3A,MSL3,TDRKH,SLC2A6,IPO5,SMAD1,PCDH9,CDK18,MAPK7,PRPH,PTN,ZDHHC14,RASA3,CNKSR2,SLA,PEX26,SLC11A1,FAIM2,ATP10B,DMXL2,TRIM2,NPL,TPM2,WBP2" Drug 6892_UP NS-398; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ADD2,LTBP4,CDK13,DNAH17,BACH1,BMP7,IL33,HAP1,CACNA2D2,PICK1,AKAP7,CPS1,SH2B1,CSF1,MFAP3L,SGSM2,FEM1B,AASS,DCTN2,PRELID3A,CSPG5,MSL3,ICA1,TJAP1,KCNN1,LAMA2,MAP2,MGAT3,MN1,MSI1,MX1,MYO6,NFYA,OPRL1,PDE4D,PFKFB2,PTCH1,RPS6KA2,TRAPPC13,KIAA1107,TRIO,RPRM,UGT8,LAT2,RNF170" Drug 2834_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "NDRG2,AP2A2,SEMA6A,ALCAM,APBB2,APC,CDC14B,MARK4,SLC2A11,SYNJ1,CBFA2T2,ARHGEF2,SOCS6,LHX2,RAB28,PLAA,NRG2,CRMP1,CSF1,PDE4DIP,DAPK3,SPOCK2,DTNA,ING4,ZNF589,FGFR1,EFCAB2,OGA,TDRKH,ELOVL5,MAP4,MEIS2,MITF,ADAM22,ZNF862,PLTP,PRKAR1B,RELN,PTN,ASAP3,SNCA,KDM4C,UNC5B,ATP10B,TROVE2" Drug 5769_DN Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.38E-06 1.92E-01 1.50E-04 1.69E-03 45 199 "ACTN1,ADRA1D,ADRB2,APBB2,APC,PPFIA3,BCL7A,ABI3BP,CREM,CSF1,RUBCN,DCAF8,RUSC2,C2CD2L,SPOCK3,DPH1,HIPK3,OPTN,C3orf18,SPEG,FGFR1,SCARA3,IQCG,SRCAP,TDRKH,TJAP1,KIF2A,LYRM9,NF1,NPR2,PFKFB2,MINDY2,PPP5C,SUGCT,ASAP3,FUZ,ZHX3,DDN,SZT2,DNAH7,TIAM1,TNS1,HIRA,UGT8,KCNAB1" Drug 6664_DN Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "BIN1,SYNJ2,ARHGAP33,ABCG1,PDE4DIP,TBC1D5,DBT,FBXL5,EXOG,HIPK3,FCF1,CELSR3,TENM1,EPB41L2,VPS26C,SCML2,FYN,GAD1,LPAR4,GRM8,HLF,KHK,MPP2,NDP,NF1,SLC11A2,NLE1,PTPRE,PID1,NUDT11,KIRREL1,ZNF671,MAPK12,FBXO11,ELOVL4,IQCE,ZEB1,TNS1,SMUG1,TRIO,VGF,WIPF1,SEMA3B,TIGD6" Drug 3432_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "SRPX,DOC2A,APBA2,APC,PDE8B,ATP6V0A1,CFLAR,ARHGEF7,C5,CA4,CLGN,CACNA2D2,PICK1,RCHY1,CNTNAP2,DZIP3,GPRASP1,DTNA,HIPK3,ACSL4,KAT8,FGFR1,PDLIM5,TRAF3IP2,GCNT2,GLYR1,KHK,MBD1,MIA2,KITLG,MX1,LYRM9,NPR2,PLXNB1,RGS3,ZNF821,CLSTN2,PLCB1,IQCE,PCDHA6,TK2,ZNF45,SPHK2,SLC30A3" Drug 7229_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "AK2,GAS7,ARRB1,SCAPER,CAMK2B,ARHGEF1,CBFA2T2,SRSF11,SOCS6,TPP1,HAPLN1,CSNK1E,PPP6R2,DCAF4,BRINP1,EGFR,MBNL2,HSD17B14,OLFM1,BAIAP2,GLYR1,POLL,PRUNE2,GPER1,GRM8,NPR2,PRODH,PRPH,WDR25,ZSCAN32,CRTAC1,PREX2,KDM4C,PLCB1,SYT5,EXOC7,PCDHGA10,CRTC1,ZNF34,TK2,RUNDC3B,LAT2,SLC17A7,RNF170" Drug 3614_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "AP2A2,NME5,ALCAM,DOC2A,BIN1,CFLAR,RAB28,BAG4,SH2B1,GREB1,HIPK3,SUGP2,ZNF589,FGFR1,CGREF1,DISC1,USP19,GNG4,SPACA9,MAP4K5,INPP5B,KCNN2,MMP16,NF1,PFKFB2,MAPK7,PRPH,RGS12,KCTD17,GSTCD,TCP11L1,ANKRD6,BTBD7,CXXC4,SMARCD3,DOK5,UNC5B,PLCB1,TBCEL,FAM155A,FLRT2,EVI5,KAT6A,PHTF2" Drug 2294_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "ABHD6,ARRB2,MARK4,CFLAR,CA4,PLEKHB1,VAX2,QKI,AKAP7,ARMC8,C2CD2,GPRASP1,DAPK3,DTNA,CINP,FAM49B,PRELID3A,HTATSF1,CNTRL,HNMT,ITPKB,JAK2,MBNL1,MIA2,LYRM9,NF1,NFYA,RETREG1,PRKAB2,TMEM104,ELOVL2,FBXO11,ANKRD6,PPP4R3A,BTBD7,SPTAN1,TSPYL2,TROVE2,SS18,TACC1,TRIM2,SLC44A1,TMPO,HPS4" Drug 4616_DN Bisacodyl [603-50-9]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "ABR,SHROOM2,MARCH3,SYNJ2,MYRF,KRIT1,ARHGEF1,TAOK2,STOML1,HOMER3,NRG2,CPS1,FAM169A,SLITRK5,ARHGAP24,ZNF337,KIAA0753,RCAN1,EIF5,ZNF589,POLR1B,SEMA4D,ANKFY1,ZNF274,ZNF276,GUCY1A1,MUM1,FAM69A,KIF2A,MITF,NDP,CCSER2,ZSCAN32,PTPN13,PTPRN2,TRIM68,LIMCH1,CEP68,PLCB1,IQCE,SMUG1,NDRG4,ZFAND5,FZD3" Drug 6100_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "RALGAPA1,LTBP4,LGR5,PLA2G4C,ATP1A3,GYG2,BAIAP3,LDLRAD4,CFAP410,CLDN10,CBARP,WHRN,NCOR2,CNTNAP2,RIPOR2,INTS1,RASGRP2,NSG1,ERAP1,ALDH1L1,SRCAP,HPGDS,PRUNE2,LILRA2,STON1,GSN,ATXN2L,MMP16,NOVA2,PCBP3,NTRK2,RETREG1,PURG,LRRN3,TRIM68,TCP11L1,RPS6KA2,ASAP3,CCDC88A,OGDHL,SNCA,TK2,PIK3R5,TRPM2" Drug 3634_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "AP2A2,APLP1,APOC1,DNAH17,RASL11B,ALDH7A1,BAIAP3,CA12,CLGN,CRY2,MFAP3L,DTNA,TSPAN5,EDNRA,CNNM1,SUGP2,PLXNC1,PDLIM5,CGREF1,FYN,GPER1,CNTRL,KCNN2,MIA2,PFKFB2,RETREG1,PLCD1,PPP5C,TMEM104,ZSCAN2,KCTD17,TCP11L1,ZNF821,CXXC4,SMARCD3,DOK5,KDM4C,ARHGAP26,TBCEL,DOCK9,PCDHA5,DNAH7,ZKSCAN5,MAP3K12" Drug 6102_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "ASIC1,ADORA1,NME5,TRMT9B,CFLAR,BMP7,CFAP410,CA4,CACNA2D2,FOXN3,ABI3BP,JAKMIP2,ZNF804A,DUSP9,C3orf18,ERCC2,FGFR1,SEMA4D,GPER1,GRM8,RASSF8,ATXN2L,ELOVL5,TM6SF1,MPP2,ADAM22,NF1,ZNF821,SH3GL3,ASAP3,NLGN1,FAM214B,SLC6A8,KDM4C,ARHGAP26,PHLDB1,SUPT5H,SYN2,TBCEL,TK2,PARD3,TPM1,PLPPR2,KAT6A" Drug 7364_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "APC,APLP1,PPFIA3,MYRF,HIP1R,SOCS6,HOMER3,TBC1D5,KLHL3,CDON,DTNA,FEM1B,TNK2,ZNF589,CINP,DLL3,GAD1,SEPT9,HAS2,KHK,PDE1C,PDE4A,KCTD15,MBOAT7,MAPK7,RIPOR1,RGS3,KIF16B,ANKRD6,SMARCC2,IFT122,NMNAT2,DBNDD2,WSCD1,SZT2,SYNE1,TNS2,TIAM1,TK2,FAM155A,LMF1,PRDM10,SMIM8,PHTF2" Drug 5024_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "ALCAM,PLA2G4C,CFLAR,BMP7,CA12,SLIT2,LHX2,ENTPD4,CSF1R,PDE4DIP,DOCK4,DCAF8,MFAP3L,ANKMY1,ACSL4,FECH,FGFR3,BAIAP2,PRELID3A,USP19,ZNF276,MSL3,FERMT2,GPR37,INPP5B,IPO5,MAP4,MYO9A,SLC11A2,RETREG1,LRP12,PRPH,WDR25,CEP97,ROBO1,CPEB3,ZKSCAN3,CDK19,SPART,STX1A,PLCB1,CRTC1,ZNF34,KAT6A" Drug 3313_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-06 1.95E-01 1.51E-04 1.70E-03 44 193 "LTBP4,AMPD3,SEMA7A,APBA2,APC,PPP4R4,ST3GAL5,ARHGAP33,WHRN,NCOR2,SEC14L5,SPOCK2,DBT,RUSC2,CDON,EZH1,AFF2,ALDH1L1,GNG4,GRM8,SLC2A6,ICA1,KIT,LSS,NTRK2,CLDN11,PDE1C,PDE4D,CEP97,KCNIP1,SCN8A,PKNOX2,SLC9A5,TSNAXIP1,CDK19,KIAA1107,TRIM2,TNS2,HIRA,FLRT2,ZNF74,SPHK2,NT5M,EVI5" Drug 2474_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.50E-06 1.97E-01 1.52E-04 1.71E-03 43 187 "ADD2,MTUS1,SRPX,BIN1,ANK2,APBB2,SEMA4G,ST3GAL5,HIP1R,LHX2,SULT4A1,RAB26,WHRN,CREM,DOCK4,OPTN,FER,OLFM1,FGFR1,GATM,ADAM28,RUNDC3A,STON1,PCLO,GRIK5,PADI2,ITGAM,MARK1,MEF2C,PCDH9,SERPINI1,PLCL1,PMP22,BEND5,ZFHX4,ANKRD6,TMCC1,UNC5B,RGL1,STXBP1,TPM1,LAMP5,FZD3" Drug 5976_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.50E-06 1.97E-01 1.52E-04 1.71E-03 43 187 "ABHD6,NME5,KIF1A,BAIAP3,CLGN,AKAP12,CRYM,PDE4DIP,ARMCX2,JAKMIP2,FAM13A,STX2,ACSL4,BAIAP2,FYN,CYP46A1,TDRKH,STON1,PCLO,ITGA7,NEK1,PCDH9,PDE4A,ENPP2,SERPINI1,PLCD1,GRAMD1C,PRPH,RADX,GAL3ST4,RPS6KA2,SMPD3,SH3BGR,SH3GL3,WDR47,CCDC88A,ELOVL4,RGL1,RPGRIP1L,HEY1,RUNDC3B,REEP1,SLC17A7" Drug 7211_UP Isoconazole [27523-40-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.50E-06 1.97E-01 1.52E-04 1.71E-03 43 187 "NDRG2,FZD9,ADORA2A,AK2,CDC42BPA,ATP1A3,NRP2,LDLRAD4,CA4,CAMK2G,MTMR7,CBFA2T2,CRY2,CSF1,EDNRB,ST3GAL6,FGFR1,FYN,ZNF44,ALDH1L1,SRCAP,LILRA2,AP4S1,NEFM,NF1,NFYA,RETREG1,MTRF1L,ZSCAN32,ZSCAN2,ZMAT4,CCDC25,PKNOX2,BTBD7,ADGRL3,TRIM2,ZKSCAN5,FAM155A,WIPF1,ZFP37,DNALI1,KCNAB1,ITM2C" Drug 5987_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.53E-06 1.99E-01 1.53E-04 1.72E-03 42 181 "NME5,MARK4,BMP7,ST3GAL5,BAIAP3,CACNB4,USP2,CLGN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,OPTN,VPS13B,FYN,CYP46A1,RAB40B,STON1,PCLO,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PPP2R2B,GRAMD1C,PRPH,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,TSNAXIP1,THSD1,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,GDPD5,SLC17A7,ITM2C" Drug 2777_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.54E-06 1.99E-01 1.53E-04 1.73E-03 41 175 "NME5,ALCAM,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,DOCK4,ARMCX2,OPTN,MBNL2,FYN,CYP46A1,RAB40B,TDRKH,STON1,MITF,MXI1,PCDH9,TMOD2,SERPINI1,GRAMD1C,PRPH,RPS6KA2,SH3GL3,PPM1E,WDR47,FAM214B,CCDC88A,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,NPL,RUNDC3B,ZNF45,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug ctd:C020806 tetrabromobisphenol A CTD 4.94E-06 2.17E-01 1.67E-04 1.88E-03 146 900 "ASIC1,NDRG2,ELFN2,ADORA1,ADRA1D,HECW2,OSBPL6,SORCS2,USP35,ALCAM,PCDH10,SEMA7A,SHROOM2,ARNTL,RGS20,ASPA,CCAR2,ATP2A2,CACNA1G,LDLRAD4,CACNA1A,RUNX1T1,CBS,USP2,CD86,CBARP,CHN2,PLEKHB1,MS4A7,CHRNA4,ABCG2,TBPL1,RASGEF1C,CTH,BOC,HDAC9,HDAC4,DGKG,ZBTB24,ELMO1,RUSC2,C2CD2L,RAB39B,DPYSL2,DNM1L,E2F6,FRY,FAM13A,EGFR,SRPK3,STARD3NL,ENO2,LRRC17,ERBB2,SH3YL1,TUBA1B,TUBB3,FCGR1A,CHST15,FCGR3A,FCGRT,FGF1,FGFR3,AMOTL2,TVP23A,GAA,GABRG2,GCNT2,BRD8,LILRB4,LPAR4,GPER1,ATOH8,AGFG1,HSPA1L,IGF1,GAREM2,KCNB1,KCNH2,NCOA7,MAP2,MEF2C,MGAT3,MMP17,MOV10,SAMD5,MYO7A,NCF2,NEFH,NRCAM,PDE1B,TMOD2,ABCB1,PLIN1,SLC25A23,PLXNB1,PMP22,STRN3,PPARA,MAPK3,MAPK9,SLC26A11,PRPSAP2,MASP1,GDPD2,PTCH1,PTPRN,FAT4,KLHL11,SETD5,RORB,RTN1,ZNF354C,S100B,FNIP1,SH3BGR,FAM102A,NAPB,CPEB4,ANKRD36,LIMCH1,SNAP25,FAIM2,SPP1,ARHGAP26,ZC4H2,ST5,IQCE,GPRIN3,THRA,NACC2,TLR4,TMPO,PIK3R5,TPM1,ZNF346,RPRM,PLEKHH2,VIPR2,VLDLR,PCDH20,ZFP41,NDRG4,SPHK2,PLSCR4,KLHDC1" Drug 4985_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "DOC2A,EPB41L5,RGS20,MARCH3,CAMK2G,RCBTB2,SLIT2,LHX2,NECTIN3,ARHGEF4,RCAN1,EIF5,IRAK4,MRNIP,FHL1,ANKFY1,TPK1,INPP5K,GHR,PCLO,GRIK5,CACFD1,DHX35,ITPKB,JAK2,LMO2,MAPT,KITLG,MPP2,GIT1,ZNF862,NEK1,PCDH9,PDE4A,CEP97,SUSD4,ANKRD6,EPN2,ARHGAP26,THSD1,STX1A,FAM155A,SPHK2,EVI5,EPM2A" Drug 3760_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "SYN3,NDRG2,AP2A2,ANK2,KCNAB2,MYOM1,ADAM23,CALB2,RUNX1T1,SYNGR3,RAB33A,AKAP6,CSF1R,GREB1,MFAP3L,SV2B,DTNB,ING4,EPB41,CDKL3,ST3GAL6,SEMA4D,ERAP1,GNAL,GRM8,C2orf72,IL6R,ADAM22,GPR173,PRKAR1B,PTPRO,SALL1,SUPT20H,PREX2,SLC14A1,SNCA,PDZRN3,SS18,SYP,CRTC1,PCDHA5,TNS1,FLRT2,VAV1,ADAMTS9" Drug 6415_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "ADORA1,ADRA1D,ADGRF5,SEMA6A,TRMT9B,APLP1,PRX,SLC4A4,GYG2,ARHGEF1,TAOK2,RGS6,CNTNAP2,SEC14L5,DBN1,PARD6A,ANKMY1,F5,DLC1,OLFM1,AGAP2,FYB1,FYN,ZNF276,ICA1,C2orf72,TJAP1,MAP2,ZNF862,NF1,PALM,SNRK,RPS6KA2,ASAP3,SLC6A11,PEG10,CDK19,SS18,ARC,ASTN2,SIN3B,SYNE1,TUBB1,UGT8,KCNAB1" Drug 3222_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "NME5,APC,GAS7,CDC14B,CACNA1I,CFAP410,CA4,CACNB4,RAB28,FHL5,COL9A3,NCOR2,SIPA1L1,ARHGEF4,ARHGAP24,SPOCK2,MFAP3L,DMPK,TNK2,VPS13B,IGSF6,ANKMY1,HPCAL4,IQCG,PRELID3A,GALC,ADAMTS13,KCND1,MEF2C,MMP16,GIT1,NNAT,PLEC,RGS12,RPS6KA2,SLC2A5,SLC6A8,SNCA,ARHGAP26,ARC,ADGRL3,SZT2,CABIN1,CLIP2,GDPD5" Drug 5454_UP Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "ADD2,BEGAIN,APAF1,PPP4R4,BAIAP3,CACNA2D1,CNTFR,COL9A3,CPS1,NCOR2,SPOCK2,KLHL3,FEM1B,ERCC2,OLFM1,CHL1,GATM,ADAM28,GFER,RUNDC3A,GLYR1,CACFD1,ATXN2L,HLF,MYO7A,NF1,NNAT,PFKFB2,LRP12,RASGRF1,KLHDC8A,ZNF821,FAM214B,CCDC88A,PDZD2,HECW1,ARHGAP26,IQSEC2,ATP10B,ARC,SYT5,DOCK9,R3HDM1,WIPF1,KCNAB1" Drug 7367_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "APBB2,SHROOM2,ARHGDIG,SLC4A4,RUNX1T1,CACNA2D2,CNTN1,AKAP6,WHRN,AKAP5,SEC14L5,CNNM1,OPTN,ZNF391,ETV1,FGF1,SRCAP,ZNF276,GLI2,GLYR1,GRIK5,IL12A,MGAT3,ZNF862,NF1,NOVA1,NPR2,CLDN11,ZCWPW1,CSRNP3,SH3BP2,ASAP3,NLGN1,ANKRD6,SNCA,SOX15,UNC5B,SPTAN1,TROVE2,THSD1,CABIN1,CHST5,TRIO,RUNDC3B,UBE3B" Drug 3538_UP Condelphine [7633-69-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "TRMT9B,AMPD3,OGT,APBB2,CACNA1I,CFAP410,SLC16A4,ARHGAP33,SLIT2,TPP1,WHRN,ENTPD4,VCAN,CNTNAP2,GREB1,SHANK1,EDNRA,C3orf18,AGAP2,ERAP1,SIGLEC8,ADAM28,MALT1,HLF,HSF2,KCNB1,MAP4,MSR1,PLCD1,MAPK7,GDPD2,SH3BP2,CPEB3,ST6GAL1,LIMCH1,ARHGAP26,SPTB,RBM26,DMXL2,TNS2,PCDHA5,TRIO,TRO,TUBB1,EPM2A" Drug 5730_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "AGT,FAM135A,SYT13,CDC42BPA,CDK10,CACNA1G,ARHGAP33,SULT4A1,PICK1,COL9A3,AKAP5,CSF1R,PHF14,RIPOR2,HS3ST2,DTNB,EDN3,EGFR,RGS17,FGF1,FGFR1,AFF2,COPS8,LSS,MSI1,NOVA1,NRCAM,GPR173,PPP5C,GDPD2,PTPRB,RFX2,RGS3,RGS12,SLC6A8,OGDHL,SOX15,HECW1,ZC3H13,LHPP,SYN2,PCDHGB6,UCHL1,ZNF74,PARP11" Drug 3203_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "SYN3,AGT,APC,PRX,ATP1A3,NRP2,MTMR3,CACNB4,HIP1R,CDH2,HAPLN1,AATK,SIPA1L1,GPRASP1,ANKMY1,PTK2B,CORO2B,ANKFY1,SIGLEC8,LYVE1,RAB30,SYNPO,INPP5B,KCNF1,KCNJ5,AFDN,ADAM22,MYT1,CNOT4,NPTX1,NTRK2,MTRF1L,NECAB2,MBOAT7,RPS6KA2,ANKRD6,KDM4D,CDK19,ATP10B,HIF3A,AP4E1,TK2,FAM13C,NLRP3,JPH3" Drug 6128_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "APBA2,APC,CDK10,ADGRB1,RUNX1T1,ABCG2,HOMER3,ING4,SRPK3,ERBB2,EYA1,HPCAL4,AGAP2,NSG1,SRCAP,KCNMB4,GPD1,STON1,GRIN2C,SOX21,SHC3,MID1,MMP16,SAMD14,NRCAM,NTRK2,P2RY1,PNMA3,CNNM2,PSD,BCAS3,TMEM231,RFX2,CARF,FAIM2,TMCC1,KDM4B,DOP1A,IZUMO4,TSPYL2,TCF4,CRTC1,LMF1,KCNK12,SH3GLB2" Drug 6837_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "APLP1,PDE8B,ALDH7A1,ADAM23,CALB1,USP2,ARHGEF1,SLIT2,RCHY1,BAG4,PDE4DIP,DMPK,DTNA,DTNB,DUSP9,HIPK3,MBNL2,MRNIP,REEP2,KAT8,ZNF44,TMEM8B,GPER1,SPACA9,GRM2,HNMT,KCNN2,KITLG,MYO7A,NEK1,PDE1C,MTRF1L,KLHDC8A,TCP11L1,SCN8A,FBXO11,LIMS2,KDM4B,SPTB,SZT2,TNS1,TPM2,HIRA,VLDLR,LMF1" Drug 6613_UP Theobromine [83-67-0]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "ADRA1D,ADGRF5,C1QTNF3,KCNAB2,APBB2,GAS7,ATP6V0A1,FUBP1,KALRN,RUNX1T1,ARHGAP33,CHRDL1,EDNRB,IRAK4,ETV1,ANKMY1,REEP2,GALC,ADAMTS13,KCNN1,KIFC3,KIT,NOVA2,NPR2,PCDH9,PTPRB,C1orf54,RGS4,FBXW7,ASAP3,CPEB3,SLC11A1,KDM4C,SPTB,SYT5,TPM2,CHST5,TRIO,RUNDC3B,HIRA,ZNF24,ZNF74,SLC17A7,KCNAB1,NLRP3" Drug 2323_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "LTBP4,AMPD3,CDC42BPA,SEMA7A,ARRB2,MARK4,ALDH7A1,GYG2,CA12,CRLF1,CACNA2D2,QKI,NCOR2,DOCK4,DAPK3,C2CD2L,CDKL3,DISC1,GRIK5,GSTM5,ATXN2L,ITPKB,KCNN1,MMP16,GIT1,NEK1,PCDH9,PPP5C,RGS12,FERMT1,FNDC3A,FAM214B,BTBD7,MAPKBP1,ARHGAP26,TSPYL2,ELOVL4,NSD1,CRTC1,AP4E1,ZNF34,WIPF1,CLDND1,GDPD5,KAT6A" Drug 3322_UP Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "NDRG2,AMPD3,APBB2,GYG2,HAP1,FOXN3,LHX2,RAB28,AKAP7,WHRN,CSF1,ARHGEF4,PPP6R2,DCAF8,RUSC2,DTNA,CELSR3,SEPT9,GNG4,GRIK5,ATXN2L,ELOVL5,MPP2,NOVA2,PLCD1,PLTP,PPARA,GRAMD1C,PTN,RIPOR1,SBF1,FAM102A,AMBRA1,SLC9A5,ZSWIM8,ST5,PHLDB1,GPR161,SLC44A1,FLRT2,PLPPR2,KCNK12,DNALI1,HPS4,SLC17A7" Drug 2147_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "MTUS1,TRMT9B,CDC42BPA,APC,ARNTL,PTCH2,CHN2,SLIT2,LHX2,SULT4A1,PICK1,SMARCAL1,NRG2,CREM,RUSC2,SV2B,OPTN,MRNIP,FGFR1,BAIAP2,NBEA,GALC,ERAP1,SEPT9,GFER,ZNF276,GNAO1,GSTM5,KIF2A,NNAT,OCRL,PDE4A,PLCL1,ACSS3,RFX2,SBF1,CXXC4,SNCA,SPTAN1,SPTB,TSPYL2,ADGRL3,TBCEL,HIF3A,TIAM1" Drug 5474_DN Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "MTUS1,APBB2,EPB41L5,CASK,MPDZ,C5,CAMK2G,SLC25A14,LRRFIP1,MAGI1,BAG4,PPP6R2,MFAP3L,EXOG,RCAN1,EPB41L2,ANKMY1,GMPR2,TAOK3,CINP,GPD2,INPP5B,KHK,MITF,MPP2,LYRM9,NACA,SLC11A2,RETREG1,MBOAT7,RGS12,TCP11L1,ZNF821,BTBD7,SLC22A4,UNC5B,CDK19,NXT2,ARHGEF9,FAM208A,TK2,NPL,TRIO,ZNF74,HPS4" Drug 2814_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "NDRG2,CDC42BPA,KCNAB2,APC,PPFIA3,PLA2G4C,DNAH17,SLC2A11,ADAM23,KSR1,SCAPER,KALRN,HIP1R,CACNA2D2,ASIC3,HOMER3,NECTIN3,CSF1,ERBB4,FGF12,DLL3,TMEM8B,GFER,GSN,ELOVL5,IL6R,KCNQ3,MMP16,LYRM9,CLDN11,GPR85,PLCD1,PPP5C,PTCH1,PTPRO,DZIP1,LIMS2,ATP10B,TBCEL,SLC44A1,CABIN1,LAT2,XRCC4,DNALI1,SEMA3B" Drug 3765_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "RALGAPA1,ASIC1,C1QTNF3,SPARCL1,CDC14B,CDK10,PTCH2,BTK,LDLRAD4,KALRN,CAMK2B,CH25H,RUNX1T1,CNTFR,RCHY1,RIMS2,BRINP1,HEPH,ING4,TNK2,RCAN2,FGFR1,SEMA4D,PDLIM5,GNG4,TPPP,GRIK5,GRM2,SOX21,IRF8,C2orf72,IGF1,AFDN,MMP16,MMP17,NOVA2,MRAS,CNKSR2,SLA,IQSEC2,NFASC,ADGRL3,PDIA2,EVI5,KCNAB1" Drug 7046_DN PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "APOC1,MARK4,SLC2A11,ALDH7A1,ATP6V0A1,NRP2,SCAPER,IL33,SCARB1,ARHGEF2,PLEKHB1,CNOT8,TAOK2,WHRN,COL9A3,CSF1,CSNK1E,PDE4DIP,FAM131B,PARD6A,EDIL3,COQ7,RRAGB,BAIAP2,GAD1,ERAP1,SYT17,ARFIP1,ATXN2L,LIFR,PDPK1,ZNF426,ELOVL2,RPS20,FAM102A,AMBRA1,IFT122,JMJD6,FBXW11,TCF4,TIAM1,TK2,TNS1,METTL3,MPPE1" Drug 2278_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "ALCAM,AMPH,SEMA7A,APAF1,LGR5,MARK4,SLC2A11,ATP6V0A1,GYG2,BAIAP3,CFAP410,CBFA2T2,WHRN,CREM,MFAP3L,TMCC2,EDIL3,HSD17B14,MTSS1L,DLC1,DCTN2,SIGLEC8,LYVE1,GPER1,GRM8,HLF,KIF5A,PDE4B,PURG,CEP41,SAMD9,C1orf54,RPS6KA2,ASAP3,FAM214B,PKNOX2,SLC11A1,FAIM2,HECW1,SSTR2,SYP,SLC35G2,FAM155A,UCHL1,FAM13C" Drug 3752_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "RALGAPA1,MTUS1,LTBP4,PKP4,SYNGR3,SULT4A1,ABCG1,CTH,RIMS2,MAML1,ING4,ELN,NCALD,APC2,ETV1,KAT8,FGFR1,PDLIM5,IQGAP2,GRM8,ADAMTS6,KCNB1,MAN2A2,MARK1,ADAM22,NTRK3,PCDH9,PDE4A,SERPINI1,MAPK10,MASP1,ZCWPW1,RASGRF1,GAL3ST4,ZMAT4,STUM,CPEB3,DZIP1,SLA,PREX2,COBL,ADGRL3,PDIA2,ZNF225,KCNAB1" Drug 4618_DN Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "MADD,PDE8B,STX16,CFLAR,ARHGEF7,LDLRAD4,CFAP410,SPAG9,PLEKHB1,ABCG2,BAG4,CNTNAP2,DZIP3,ARHGAP32,RCAN1,CELSR3,MBNL2,CDKL3,RRAGB,ST3GAL6,IQCG,ZNF44,DENND2A,MSL3,CACFD1,SYNPO,FAM69A,INPP5B,GIT1,MX1,PRKAR1B,BCAS3,ZSCAN2,RAD51D,FAT4,ZNF671,RPS6KA2,ATXN7,THSD1,CABIN1,LMF1,XRCC4,NDRG4,EMSY,VPS35L" Drug 3079_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "ADORA1,AMH,CDC42BPA,SEMA7A,CDC14B,DNAH17,CA8,CACNA2D1,KALRN,CHN2,ABCG1,RIMS2,USP6NL,SPOCK2,RUSC2,SUGP2,PLEKHA1,STX2,FGF13,CHL1,SIGLEC8,CPLX2,MSL3,KCNMB4,HNMT,MAP4,GIT1,TAGLN3,PFKFB4,CCSER2,MTRF1L,CEP41,ACSM5,NKAIN1,RPS20,EPN2,CXXC4,SNAP25,RBM34,MTCL1,CUX2,RPGRIP1L,SLC19A3,KCNE5,JPH3" Drug 2912_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.04E-06 2.21E-01 1.67E-04 1.88E-03 45 200 "C3orf14,ADORA1,CDC42BPA,PPP4R4,ATP6V0A1,NRP2,CACNA2D1,SCARB1,B4GALT6,TAOK2,CREM,ABCG1,OPTN,MRNIP,ST3GAL6,FER,BAIAP2,GAA,SEPT9,PCDH17,GPR75,ATXN2L,HNMT,KCNB1,KIFC3,GIT1,ZNF862,NINJ2,CEP41,MAPK10,CNNM2,DEF8,PTPRN2,PBRM1,TCP11L1,FRMPD1,EPN2,PKNOX2,TSNAXIP1,ZSWIM8,UNC5B,IQSEC2,SPART,ZFP37,SPHK2" Drug 6727_UP Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "AGT,SLC4A4,N4BP2L1,AZGP1,ADGRB2,PROM1,CAMK2A,CAPN3,RUNX1T1,SYNGR3,ARHGAP22,CREM,DBT,MFAP3L,DTNA,HIPK3,ING4,ELN,SRCAP,GFER,RUNDC3A,GNAL,GNAO1,AP4S1,PADI2,MT1M,MX1,NELL2,PDE4D,GPR85,PPARA,SAMD9,PTPRB,RGS4,PKNOX2,ZSWIM8,LMO3,ATP10B,ARC,SYN2,SYT5,THRA,TLR4,DNALI1" Drug 3854_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "NDRG2,SEMA7A,APBA2,PPP4R4,PLA2G4C,STX16,CAMK2B,LHX2,EPS15L1,STOML1,SULT4A1,NCOR2,SNCAIP,DAPK3,SPOCK2,NR1D2,DTNA,FCF1,EIF4G2,HPCAL4,AGAP2,NSG1,GDF9,GLYR1,HTATSF1,GSN,IL6ST,KCNJ5,LSS,MGAT3,KITLG,MMP17,PNMA3,LRRN3,RPS20,KCNIP1,ZFP2,PPP4R3A,HECW1,GPR161,WIPF1,ZNF24,PARP11,HRASLS" Drug 4171_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "NDRG3,NDRG2,AMPD3,BIN1,BCAS1,MARK4,ALDH7A1,SCAPER,C5,CFAP410,SH2B1,SNCAIP,RASSF2,SPOCK2,EGFR,PLXNC1,ING4,ELN,ERCC2,CDKL3,PIPOX,FGFR1,AFF2,PRELID3A,GAD1,SEPT9,PRUNE2,ELOVL5,KIT,IPO5,SMAD1,ADAM22,MYT1,NEK1,PRKAR1B,MAPK10,SAMD9,CCDC25,SH3GL3,PEX26,RBM34,TRIM2,VIPR2,XRCC4" Drug 6705_DN Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "BIN1,APC,KIF1A,KRIT1,ARHGEF2,QKI,DZIP3,TM9SF4,TBC1D5,CHRDL1,FCF1,MBNL2,VPS26C,ZNF589,FGFR1,ANKFY1,TRMO,CNTRL,FAM69A,LIG4,PLCD1,POLR2F,CLIP1,MAPK12,FUZ,PPP4R3A,ELMO2,ZNF667,LIMCH1,NMNAT2,ZBTB43,SS18,NXT2,IQCE,SYNE1,TMEM121,TPM2,TRIO,CLDND1,XRCC4,UBE3B,KAT6A,SMIM8,PHTF2" Drug 6021_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "NDRG2,AK2,AMH,CDC42BPA,ARRB1,DNAH17,ALDH7A1,ADAM23,CFLAR,KSR1,GYG2,ARHGAP33,QKI,CNTNAP2,CDON,KAT8,IQCG,FAM49B,GAD1,DISC1,GLYR1,GRM8,ITPKB,MITF,NF1,MINDY2,SAMD9,MRAS,PREX2,EPN2,SLC6A8,BTBD7,CXXC4,COA1,TROVE2,EXOC7,CRTC1,PCDHA5,VAV1,XRCC4,ZFP37,GDPD5,KCNAB1,SENP7" Drug 2789_UP Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "ADORA1,TRMT9B,AMPD3,PLA2G4C,ST3GAL5,BAIAP3,PTBP2,CBFA2T2,TAOK2,WHRN,RCHY1,NECTIN3,RIMS2,HSD17B14,REEP2,FAM198B,PTK2B,FGF12,FGFR1,ERAP1,MSL3,GPER1,GRIK5,GSTM5,ICA1,MAP4,MAPT,NELL2,PFKFB2,PRKCB,MAPK7,GRAMD1C,PTX3,TRIM68,RNASEL,TCP11L1,SYBU,EPN2,SLC6A8,TTBK2,EXOC7,SZT2,CABIN1,KAT6A" Drug 896_UP 5152487; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "BIN1,APAF1,APBA2,CDC14B,CDK13,ATP2B2,BAIAP3,LDLRAD4,CA4,CAMK2B,ARHGEF1,CDH2,HOMER3,ARHGEF4,TBC1D5,CELSR3,COQ7,FHL1,IQCG,PDLIM5,AHDC1,TOX3,GNG4,LPAR4,CNTRL,IFI16,LMO2,MAP4,AFDN,KHDRBS2,RPS6KA2,SCN2B,FNDC3A,RBM34,KDM4C,CLSTN2,CEP68,KIAA1107,TNS2,CHST8,AP4E1,SMUG1,KCNK12,UBE3B" Drug 6090_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "C1QTNF3,ALCAM,APOC1,ARHGDIG,ARRB1,MARK4,GYG2,ARHGEF2,HOMER3,PDE4DIP,RUSC2,DUSP9,HIPK3,ING4,STX2,NCALD,RRAGB,ZNF589,CGREF1,SRCAP,ZNF276,GPER1,GRB10,MBD1,MID1,NEK1,NF1,PCDH9,PRKAR1B,ZSCAN2,PEX26,EPN2,LIMS2,FAM214B,SLC6A8,CDK19,TSPYL2,VPS13A,SYN2,EXOC7,ZNF34,CABIN1,ZFP37,SENP7" Drug 3071_UP Estrone [53-16-7]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "ABHD6,SYT13,APC,CDK13,DNAH17,BMP7,RUNX1T1,NRG2,CREM,CRY2,ABCG1,CRYM,SIPA1L1,PDE4DIP,DOCK4,DMD,C3orf18,ETV1,PTK2B,DLC1,FGFR1,SEC23B,PDLIM5,ALDH1L1,COPS8,HNMT,DHX35,TJAP1,MAP4,AFDN,TAGLN3,MX1,NTRK2,OPRL1,PNMA3,CNNM2,PTK2,PTPRN2,ZMAT4,KCTD17,GALNT10,SH3BGR,ARHGAP26,IQSEC2" Drug 5755_DN Racecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "RALGAPA1,APLP1,ALDH7A1,CFAP410,CBFA2T2,CRLF1,MFAP3L,SGSM2,EIF4G2,TENM1,STX2,ETV1,EZH1,B4GALNT1,AHDC1,USP19,GLYR1,TDRKH,KCNH2,MIA2,ZNF862,NEK1,RETREG1,NLE1,SAMD9,SUGCT,ZNF671,RPS6KA2,MRAS,SH3BGR,FAM102A,SLC2A5,LIMS2,CCDC88A,SNCA,CEP68,ZEB1,TNS2,CABIN1,ZNF74,NDRG4,REEP1,MAP3K12,EPM2A" Drug 2055_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "ADORA1,AMH,AMPD3,ALDH7A1,KSR1,BMP7,CACNA1I,C5,BAIAP3,CFAP410,CSF1,DTNA,EGFR,MRNIP,MTSS1L,F5,SEMA4D,SIGLEC8,GLI2,MSL3,POLL,GNAO1,GPR37,KCNJ5,ADAM22,MSR1,MYO7A,P2RY13,PDE4D,RETREG1,PRKAR1B,KHDRBS2,RFX2,STUM,SLA,DOP1A,SPTB,DDN,CLSTN2,IQCE,OSBP2,MAP3K12,EVI5,SLC17A7" Drug 3184_DN Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "EP400,APC,ARRB2,MARCH3,ATP6V0A1,CFLAR,CFAP410,MAGI1,SOCS6,TAOK2,FAM189A2,ARHGEF6,BAG4,LRIG1,KIAA0586,FBXL5,TOM1,EDNRA,DENND4A,FECH,FGFR1,SEMA4D,CGREF1,GALC,ERAP1,POLL,PADI2,KCNF1,MIA2,NF1,NFYA,PRKAR1B,GTDC1,THSD1,STX1A,ASTN2,FBXW11,TRIM2,CABIN1,HIRA,VAV1,VIPR2,ZNF45,GDPD5" Drug 2311_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "NME5,CFLAR,MTMR3,CACNA1A,CAMK2B,NRG2,SNCAIP,DGKG,DMPK,SHANK1,RASGRP2,ERCC2,SPEG,PTK2B,ZNF589,OLFM1,FHL1,FOXF2,LYVE1,PRUNE2,SOX21,MBD1,KITLG,ADAM22,MX1,NTRK2,PLCB2,PPARA,PTCH1,ZFHX4,PLPPR3,STUM,SLC11A1,OGDHL,LIMCH1,SPP1,ARC,TBCEL,AMACR,TRO,DNALI1,SLC17A7,KCNAB1,ST7" Drug 4105_DN Fusaric acid [536-69-6]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "LTBP4,BIN1,PDE8B,MTMR2,CAMK2G,CCNT1,SCARB1,B4GALT6,QKI,HOMER3,ABI3BP,CREM,SIPA1L1,ING4,ANKMY1,ACSL4,ZNF589,FHL1,OGA,HTATSF1,FERMT2,STON1,IPO5,MAPT,THYN1,CNOT4,SETD4,PDPK1,RIPOR1,RGS3,RPS6KA2,CLIP1,FNDC3A,PPP4R3A,EPN2,SS18,PLCB1,TMPO,KAT6B,CABIN1,CLDND1,TFIP11,UBE3B,IFT88" Drug 7493_UP ST021200; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "ASPHD1,SYT13,PKP4,APBB2,AQP6,CDK10,MARK4,ADAM23,CBARP,FOXN3,STOML1,RAB26,CYBB,EDIL3,FEM1B,TUBD1,BAIAP2,IQCG,SEMA4D,TRMO,CGREF1,RUNDC3A,GRIK5,CNOT4,GPR85,KCTD15,NLE1,PRKCB,CNNM2,PTPRH,TMEM231,FAT4,KCTD17,OGDHL,TSNAXIP1,ZHX3,SYP,TCF4,THRA,TNS1,TRIO,LMF1,MAP3K12,ADAMTSL3" Drug 4219_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "BAG4,VCAN,FAM169A,SLITRK5,TBC1D5,DBT,MFAP3L,KIAA0753,PLPPR4,CHRDL1,EXOG,COQ7,SPEG,ETV1,RRAGB,POLR1B,FGF13,ERAP1,GCNT2,GPD2,TDRKH,AGFG1,SHISAL1,FAM69A,NDP,CLDN11,RETREG1,PTPRN2,RAD51D,BEND5,SBF1,FBXO11,FNDC3A,LIMCH1,ARHGEF9,IQCE,TRIM2,DNAH7,TK2,RUNDC3B,SSBP2,XRCC4,NDRG4,PLSCR4" Drug 4455_DN 15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-06 2.25E-01 1.68E-04 1.89E-03 44 194 "C1QTNF3,LTBP4,CDC42BPA,PPP4R4,MARK4,ADGRB2,IL33,ARHGAP33,CHN2,NRXN3,WHRN,PPP6R2,FAM131B,TBC1D5,ARMCX2,EGFR,PLXNC1,ETV1,FGF1,SEMA4D,GAD1,ERAP1,INPP5K,GPR37,CNTRL,JAK2,MEF2C,GIT1,TAGLN3,NF1,CLDN11,PDE4D,PFKFB4,PLCB2,MINDY2,CSRNP3,DDN,LHPP,ST5,WSCD1,SYNE1,TNS2,DNAH7,SPHK2" Drug 5511_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.26E-06 2.30E-01 1.72E-04 1.93E-03 42 182 "ABHD6,NME5,CDC14B,ST3GAL5,GYG2,CLGN,AKAP12,PDE4DIP,ARMCX2,TSPAN5,FAM13A,FYN,CYP46A1,RAB40B,STON1,ICA1,MITF,MXI1,SERPINI1,SLC25A23,PRPH,GAL3ST4,ROBO1,RPS6KA2,SH3GL3,SYBU,WDR47,FAM214B,PKNOX2,CCDC88A,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,ZKSCAN5,SLC30A3,EVI5" Drug 6546_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.28E-06 2.32E-01 1.72E-04 1.94E-03 41 176 "ADRB2,ARNTL,ADGRB2,ST3GAL5,HIP1R,USP2,NRXN3,ABCG1,PDE4DIP,CNTNAP2,CTH,C2CD2L,PLPPR4,RGS17,EPB41L2,TBC1D16,PTK2B,TAOK3,BAIAP2,HPCAL4,FYN,RUNDC3A,STON1,GUCY1B1,MMP16,PCDH9,SERPINI1,CCSER2,PRPH,RGS4,RPS6KA2,SH3GL3,SAMSN1,THSD1,ELOVL4,RGL1,SYT1,SSBP2,HIRA,TRIM9,SLC30A3" Drug 5441_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.28E-06 2.32E-01 1.72E-04 1.94E-03 41 176 "NME5,ST3GAL5,BAIAP3,USP2,CLGN,CRYM,PDE4DIP,ARMCX2,JAKMIP2,TMCC2,SLC12A6,OPTN,FAM13A,RASGRP2,STX2,FYN,CYP46A1,RAB40B,STON1,MXI1,TMOD2,SERPINI1,MAPK10,PRPH,SMPD3,SH3GL3,WDR47,FAM214B,PKNOX2,ARHGAP26,THSD1,RGL1,STXBP1,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,SLC30A3,SLC17A7,ITM2C" Drug 4565_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.28E-06 2.32E-01 1.72E-04 1.94E-03 41 176 "ADRB2,MTUS1,ARNTL,ADGRB2,ST3GAL5,HAP1,HIP1R,USP2,CHN2,ABCG1,PDE4DIP,CNTNAP2,CTH,PLPPR4,PTK2B,TAOK3,BAIAP2,PDLIM5,FYN,SCIN,FAM69A,ITGA7,MMP17,TAGLN3,SERPINI1,RETREG1,PRPH,PTCH1,PTPN13,RGS4,FBXW7,SH3GL3,FNBP1,THSD1,RGL1,SYT1,COBL,KIAA0930,RUNDC3B,TRIM9,PLSCR4" Drug CID000004597 o-nitrophenyl beta-D-fucopyranoside Stitch 5.53E-06 2.42E-01 1.80E-04 2.03E-03 23 75 "AP2A1,AP2A2,AMPH,NUMB,SYNJ1,HIP1R,NUMBL,EPS15L1,CLTC,SNAP91,DNM1,DNM1L,SH3YL1,GALC,AGFG1,NPY,OCRL,OPA1,EPN2,SYP,SYT1,SYNE1,WIPF1" Drug 5763_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "NME5,SLC4A4,ALDH7A1,MYRF,CA8,CRLF1,RAB28,SULT4A1,ARHGEF10,ARHGAP24,MFAP3L,DRP2,DTNA,TENM1,LRRC17,FGFR1,BAIAP2,SEMA4D,ZNF276,INPP5B,LIFR,MAP2,MMP16,GIT1,NDP,NOVA2,NPR2,CNNM2,SAMD9,FAM184A,SUGCT,SALL1,MRAS,SNCA,ZNF415,ZHX3,DDN,ZEB1,CABIN1,TNS1,REEP1,MAP3K12,TIGD6,DPF3" Drug 3719_DN Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASIC1,APC,CDK10,ADAM15,ADGRB2,MYRF,CACNA1A,PLEKHB1,TAOK2,ARMC8,SNPH,ARHGAP24,DAPK3,PARD6A,DMPK,CDON,DTNA,ING4,ETV1,SEMA4D,ANKFY1,PRELID3A,MSL3,TDRKH,CACFD1,SHISAL1,KIFC3,MAP2,MAPT,MT1M,SLC11A2,PDE4B,PTCH1,PTN,TCP11L1,SPTAN1,CEP68,DOCK9,AMACR,TFIP11,NT5M,PCBP4,AAAS,RNF146" Drug 5113_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "TRMT9B,PPFIA4,DDO,ADGRB1,NRP2,RUNX1T1,CSF1R,SPOCK2,MFAP3L,EXOG,DTNA,TOM1,HIPK3,COQ7,NRN1,FGF1,ZNF44,GATM,POLL,LPAR4,SPACA9,HLF,ICA1,TJAP1,ITGA7,MAPT,MPP2,PDE4B,SNRK,ELOVL2,PTPRN2,ZSCAN2,TMEM231,KHDRBS2,GAL3ST4,RGS12,TCP11L1,RPS6KA2,ZNF821,SLC4A3,PCDHGA10,TK2,CDK20,LAT2" Drug 4558_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "AMT,EPB41L5,GAS7,ATP6V0A1,ASIC3,B4GALT6,NRG2,ENTPD4,SH2B1,SUSD5,DTNA,EDNRB,EIF4G2,OGA,FYB1,ERAP1,ALDH1L1,GLI2,IRAK3,INPP5B,MAP2,AFDN,MYCN,PFKFB2,SERPINI1,DCHS2,PTPRH,CCDC40,RASGRF1,RFX2,CCDC102B,MRAS,KANSL3,ZHX3,TRIM2,THRA,TK2,VIPR2,VLDLR,SLC17A7,KCNAB1,FAM13C,PHTF2,JPH3" Drug 4373_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASPHD1,ALK,BIN1,PDE8B,ATP2A2,MTMR3,GYG2,CACNA1I,CBFA2T2,CNTFR,AATK,PHF14,MFAP3L,EDNRA,HIPK3,PLXNC1,ING4,TNK2,RASGRP2,OLFM1,FGFR1,SCARA3,AGAP2,ANKFY1,GNG4,KHK,MAP2,MID1,GIT1,NF1,NPTX1,PLXNB1,ELOVL2,FAM184A,TCP11L1,DOP1A,TSNAXIP1,SPTAN1,JMJD6,WSCD1,PCDHA6,GPR161,TRIO,ITM2C" Drug 4220_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "MTUS1,PDE8B,ST3GAL5,C5,ARMC8,BAG4,ENTPD4,PDE4DIP,TBC1D5,DBT,MFAP3L,PLPPR4,PARD6A,FCF1,ZNF391,ETV1,RRAGB,ZNF589,MSL3,TDRKH,FAM69A,MBD1,MIA2,TAGLN3,NDP,CLDN11,ENPP2,RETREG1,RAD51D,FAT4,BEND5,SUPT20H,FBXO11,ST6GAL1,NLGN1,LIMCH1,CDK19,TCF4,THRA,VGF,WIPF1,ZNF711,MPPE1,PHTF2" Drug 6415_UP Orlistat; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ADD2,BIN1,CDK13,ADGRB2,SYNJ2,CHN2,CSF1,VCAN,C2CD2L,HIPK3,SPEG,DLC1,FYN,DISC1,GCK,GFER,TOX3,MSL3,GRM2,INPP5B,KCNN1,LIFR,FXYD7,NF1,PLCD1,PTH1R,PTPRH,CCDC40,RGS4,KCTD17,RPS20,STUM,FNDC3A,ST6GAL1,ZKSCAN3,UNC5B,SPTAN1,JMJD6,CUX2,TRIO,TRO,FAM155A,WIPF1,ITM2C" Drug 4181_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASIC1,CDC42BPA,SEMA7A,APC,APLP1,CDK10,DNAH17,CRLF1,CNTFR,CRMP1,RIMS2,HIPK3,PLXNC1,ING4,ELN,STX2,ERCC2,ANKMY1,DLC1,OLFM1,FAM49B,KHDRBS3,AHDC1,LYVE1,ADAMTS13,KCNN1,NNAT,PDE1C,PPP2R2B,MAPK10,GTDC1,SLC6A8,ZHX3,PLCB1,ARC,SYT5,SIN3B,SZT2,FLRT2,WIPF1,KLC2,XRCC4,ZFP37,EPM2A" Drug 2504_UP Skimmianine [83-95-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ACHE,ALK,BIN1,SEMA7A,APBB2,EPB41L5,SEMA4G,PDE8B,ATP1A3,AZGP1,FUBP1,BAIAP3,CBFA2T2,DLGAP1,EPS15L1,RAB33A,ABCG2,NCOR2,RGS6,RIMS2,HS3ST2,EDN3,EDNRA,AASS,DLC1,ZNF44,DENND2A,GAD1,GLI2,GLYR1,TAGLN3,MYO6,ABCB1,PKIA,TCP11L1,LIMS2,PDZRN3,SOX11,SPTB,CLSTN2,PLCB1,TRIM2,FAM155A,KCNK12" Drug 3885_UP Flutamide [13311-84-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASIC1,C1QTNF1,SEMA6A,AMPD3,FGD2,APAF1,BACH1,ADGRB1,LDLRAD4,RUNX1T1,TPP1,LY86,VCAN,SPOCK2,HEPH,EDN1,C3orf18,RASGRP2,DLC1,AGAP2,GATM,GLYR1,PCLO,TPPP,INPP5B,MMP16,ADAM22,MAPK7,ZSCAN32,SCN8A,SH3BP2,CPEB3,LIMS2,SLC11A1,TBL1X,WSCD1,DOCK9,SLC35G2,HEY1,HIRA,VIPR2,LAT2,PLSCR4,SENP7" Drug 4070_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ADAM15,ADGRB3,NRP2,BMP7,CACNA2D1,CAMK2B,RUNX1T1,STOML1,CSF1R,PHF14,ARHGEF4,C2CD2L,SPOCK3,RASGRP2,APC2,PIPOX,FGF12,HPCAL4,PDLIM5,PRELID3A,CSPG5,GABRB3,NEU3,RUNDC3A,GNAO1,TAGLN3,NF1,NTRK2,SMOX,PPP2R2B,PTCH1,PTPRN2,ACSS3,CCDC40,SUSD4,RGS12,RNASEL,SCN2B,ASAP3,FAM214B,SLC14A1,SNCA,KIF13A,AP3B2" Drug 3346_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "NME5,CDC42BPA,LDLRAD4,CALB1,CAMK2B,ARHGEF2,FOXN3,SULT4A1,PICK1,AKAP7,NCOR2,CYBB,RUSC2,CNNM1,MBNL2,EGR3,ERCC2,FAM198B,SCML2,FHL1,FYN,SRCAP,GPER1,ADAMTS13,GSTM5,ICA1,IL6R,INPP5B,MAPT,MGAT3,MX1,NOVA2,PCBP3,TREM2,LRP12,KHDRBS2,RPS6KA2,DZIP1,KANSL3,PKNOX2,CCDC88A,KDM4B,WSCD1,DMXL2" Drug 5093_DN Carbamazepine [298-46-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "AMT,STX16,ADGRB2,FUBP1,CACNA1A,SCARB1,SLC4A8,RCHY1,CPS1,CSF1R,ARHGAP24,BRINP1,SGSM2,CDON,EDIL3,FCF1,EGFR,MBNL2,MTSS1L,ANKFY1,OGA,GLYR1,MSL3,GPD2,PCLO,AGFG1,KCNN1,MAPT,MMP16,NF1,CLDN11,PCDH9,GSTCD,LIMS2,SNCA,NXT2,JMJD6,DNAH7,XRCC4,ZNF711,ZNF24,SEMA3B,KAT6A,SENP7" Drug 6761_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASPHD1,MTUS1,C1QTNF3,GAS7,DDO,N4BP2L1,IL33,CLDN10,CRYBB1,VCAN,PHF14,ZBTB24,PLPPR4,SGSM2,ING4,FGFR1,ERAP1,GSTM5,ELOVL5,TM6SF1,ADAM22,LYRM9,NOVA2,NTRK2,P2RY1,RETREG1,MAGEL2,POU6F1,PTPRN2,TMEM231,MARCH1,MCMBP,FBXO11,ANKRD6,ZHX3,IQSEC2,ASTN2,TAL1,PCDHGA10,TPM1,FLRT2,KCNAB1,EPM2A,JPH3" Drug ctd:D007608 Kainic Acid CTD 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "DGCR6,ADRA1B,APAF1,MPDZ,NRP2,CALB1,KALRN,CCK,CHGB,ABCG2,QKI,CNR1,PICK1,CNRIP1,GRIN3A,FGFR1,SEMA4D,GABRB3,GAD1,GCNT2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,IL12A,ITGAM,JAK2,MAP2,MYO9A,NFE2L2,NPY,SLC11A2,NTRK2,ABCB1,FXYD1,MAPK3,SNRK,ATF7IP,SPTAN1,SST,ARC,SIRT1,UCHL1" Drug 3669_DN Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ACTN1,ADRB2,ALK,APC,CDC14B,CDK13,SLC4A4,SCAPER,SEPT7,CACNA2D2,IQCK,VCAN,CNTNAP2,HDAC9,CDON,FEM1B,CDKL3,FGF1,OGA,CACFD1,RNFT2,GUCY1B1,TJAP1,KCNB1,FSD1,PTN,GAL3ST4,SCN8A,AMBRA1,ELMO2,ZNF415,THSD1,SS18,ASTN2,EXOC7,PDLIM2,CDK20,TPM2,PLPPR2,LAT2,WNT7A,TFIP11,KAT6A,RNF146" Drug 2333_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ADGRF5,BEGAIN,DOC2A,AMT,LGR5,CDK13,MARK4,BACH1,CFLAR,SYNJ2,C5,ARHGEF1,PDE4DIP,ZFYVE16,SPOCK2,RCAN1,EIF4G2,COQ7,ERBB2,PRKAG2,FHL1,ANKFY1,ERAP1,SIGLEC8,GRB10,ITGAM,MAP4,MBP,AFF1,SMOX,KLK6,CNNM2,GDPD2,PTCH1,RIPOR1,RGS3,RXRA,SEC14L1,BTBD7,DOK5,PBLD,CHST8,KAT6B,KCNK12" Drug 4696_UP Ofloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "NME5,ALCAM,AMPD3,CDC42BPA,CDK13,SCAPER,CALB2,TAOK2,NRXN3,CREM,CSF1,CNTNAP2,ARHGAP24,EDN3,EDNRA,NRN1,FGFR1,GLYR1,TOX3,GPER1,GRB10,GSTM5,HLF,INPP5B,IPO5,MID1,MYCN,PDE4B,SLC25A23,RORB,ZFP2,ASAP3,CCDC88A,ZKSCAN3,ZNF415,RBM26,PLCB1,WSCD1,DMXL2,PCDHA5,THRA,CHST5,WIPF1,SLC17A7" Drug 4272_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "APOC1,SYNJ2,SCAPER,SPAG9,KRIT1,CCNT1,WHRN,CNTNAP2,MBNL2,RRAGB,FYN,GAD1,SPIN1,FERMT2,AGFG1,IFI16,IL6ST,FAM69A,JAK2,MMP16,TAGLN3,MYO6,NFIX,PCDH9,PIK3R1,CCSER2,SMIM7,STRN3,LRP12,PRKAB2,PTN,RGS4,SLC25A36,FBXO11,SPTAN1,PBLD,KIAA1107,TCF4,DICER1,TMPO,NAV3,KCNAB1,EPM2A,FXR1" Drug 3610_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "SPARCL1,GAS7,N4BP2L1,CACNA2D1,ENTPD2,NCOR2,FAM169A,DGKG,GIT2,DTNA,EDN1,EDN3,ERCC2,FGF1,FGFR1,AFF2,FOLR2,KHDRBS3,ALDH1L1,ADAM28,MGAT3,ZNF862,NCF2,NF1,CDK18,ENPP2,PLCD1,SH3BP2,HKDC1,PKNOX2,LIMCH1,PDZD2,IZUMO4,UNC5B,ZNF423,SPTB,TACR1,WSCD1,PCDHGB6,CRTC1,TIMP4,UCHL1,WNT7A,SPHK2" Drug 4845_UP Primaquine diphosphate [63-45-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ACHE,NDRG2,CDC42BPA,GAS7,DDO,DNAH17,SLC4A4,ADAM23,KSR1,CBFA2T2,CDH2,LHX2,NRG2,CSF1,SEC14L5,MFAP3L,DRP2,AASS,ELN,ACSL4,DLC1,ST3GAL6,LYVE1,GNAL,MID1,ADAM22,NACA,NTRK2,OPRL1,MTRF1L,POU6F1,PPARA,RELN,KHDRBS2,MYH15,IQSEC2,DDN,ATP10B,ARC,ADGRL3,OSBP2,VIPR2,LAT2,NT5M" Drug 4624_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ADD2,LTBP4,CDC42BPA,SEMA7A,KSR1,GYG2,CACNA1G,CA4,EPS15L1,TPP1,WHRN,AATK,VCAN,C2CD2L,EDNRA,EBI3,DLC1,KAT8,AGAP2,CSDC2,RUNDC3A,GNG4,PRUNE2,GRM8,IRAK3,JAK2,PACRG,ADAM11,MMP16,MYO7A,CNOT4,NTRK3,FA2H,SNRK,MARCH1,SEMA6D,ZFP2,SNCA,SP2,ATP10B,PHLDB1,TACR1,PHF24,VGF" Drug 3620_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "APOC1,CDK13,MARK4,PTCH2,CAMK2B,USP2,COL9A3,SH2B1,RIMS2,ARHGAP24,TMCC2,DPP6,ECM2,C3orf18,ERCC2,FGF1,CPLX2,ALDH1L1,IRAK3,INPP5B,KCNB1,KCNN1,MAPT,ZNF862,OGG1,PLCB2,PLCD1,C19orf57,CEP41,ACSM5,PNMA8A,STUM,RASA3,ASAP3,SLC9A5,SNAP25,NMNAT2,PEG10,ZBTB43,ATP10B,SYN2,TRIO,WIPF1,NT5M" Drug 7099_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "LTBP4,ARNTL,CDK13,MARCH3,BMP7,ST3GAL5,GYG2,NECTIN3,DAPK3,DTNA,E2F5,SEZ6L2,RASGRP1,MBNL2,EGR3,RGS17,VPS26C,ZNF589,SYT17,CRCP,MSL3,TDRKH,ICA1,KCNF1,MKLN1,LYRM9,PFKFB3,CCSER2,RETREG1,PTPRE,RPS6KA2,SBF1,ZNF821,AMBRA1,STX1A,ANKRD12,EXOC7,KIAA0930,PCDHA6,TIAM1,PARD3,CABIN1,TPM1,GDPD5" Drug 6662_UP Fluspirilen [1841-19-6]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "RALGAPA1,ADORA2A,AK2,PPP4R4,CDK13,PDE8B,ATP2B2,CFLAR,KALRN,HAP1,SLC16A4,SCARB1,LARGE1,DLGAP2,EPS15L1,SULT4A1,RIPOR2,SPOCK2,MFAP3L,EPHB1,ETV1,DLC1,OGA,PCDH17,GSTM5,KCNJ5,KCNQ3,ADAM22,MT1M,NPR2,NTRK2,OPRL1,GPR85,TCP11L1,SLC12A4,ZNF334,HECW1,ZC3H13,TACR1,MCF2L,CRTC1,ICAM5,SPHK2,KCNAB1" Drug 3237_DN Adenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "AK2,BIN1,CFLAR,MTMR2,SPAG9,USP2,TAOK2,RAB28,PLAA,CLCN3,CSF1,RCAN1,FEM1B,MBNL2,RASGRP2,MTSS1L,FHL1,ARFIP1,GRB10,GRM8,MAP4K5,AGFG1,LMO2,TM6SF1,KITLG,MMP16,MSI1,NF1,NFYA,CNOT4,PCDH9,PIK3R1,RGS12,EMID1,ASAP3,NLGN1,ELMO2,ZKSCAN3,TROVE2,FBXW11,ZNF34,TMPO,VIPR2,EVI5" Drug 3268_UP Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "NDRG2,NME5,DOC2A,TRMT9B,BIN1,APC,PPP4R4,ARRB2,SLC2A11,ALDH7A1,ST3GAL5,BAIAP3,HAP1,RCBTB2,PICK1,CNTFR,CNTN1,WHRN,GIT2,DMPK,TOM1,ACSL4,SEMA4D,ALDH1L1,ICA1,KCNH2,KCNN1,MGAT3,ZNF862,P2RX7,CNNM2,KCTD17,SLC6A8,SLC11A1,ARC,SZT2,TRO,PLPPR2,VLDLR,ZBTB14,SPHK2,SLC17A7,KAT6A,SENP7" Drug 1884_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "APBB2,PRX,KIF1A,CACNA1I,MYRF,CACNA1A,CALB2,CAMK2B,CACNA2D2,FOXN3,CHN2,STOML1,CNTFR,SH2B1,CRMP1,NCOR2,KLHL3,SUGP2,SRPK3,ELN,RASGRP2,FGFR1,SPACA9,CACFD1,LAMA2,MBP,GIT1,SAMD14,MYT1,OPRL1,DUSP26,PPARA,PPP5C,PRKCB,PTH1R,DCUN1D2,RXRA,ST6GAL1,LIMS2,ZHX3,ZC3H13,PHLDB1,VGF,WIPF1" Drug 3034_UP Capsaicin [404-86-4]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ABHD6,SEMA6A,ANK2,APBA2,DDO,PPP4R4,RUNX1T1,USP2,CHRNA4,CLTB,ABCG2,WHRN,HAPLN1,SUSD5,ZNF337,BRINP1,HIPK3,HEYL,EPB41,DLC1,AFF2,FYB1,GABRA3,MSTN,PCDH17,RUNDC3A,ZNF276,GNAO1,GUCY1A1,HLF,SYNPO,SCIN,KCNF1,FSD1,POU6F1,PPP1R1A,BCAS3,PTPRB,FERMT1,ASAP3,ARHGAP26,PHF24,CRTC1,HRASLS" Drug 6330_UP Budesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ADORA1,LTBP4,EPB41L5,SEMA4G,NRP2,HIP1R,ARHGEF1,TPP1,ARMC8,CREM,AKAP12,NCOR2,PDE4DIP,SLITRK5,PHF14,TBC1D5,SPOCK2,DTNA,FAM13A,IRAK4,PIPOX,FGF1,HPCAL4,DENND2A,POLL,IL6R,MIA2,MPP2,NF1,CNOT4,NRCAM,FSD1,MAPK7,ZFP30,CNKSR2,PKNOX2,SNCA,KDM4C,SS18,CEP68,TBCEL,TNS1,EVI5,SEMA3B" Drug 6825_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "RALGAPA1,ASPHD1,DOC2A,ARHGDIG,ARRB2,MARK4,ATP6V0A1,MTMR2,CAMK2G,TAOK2,RAB28,VAX2,QKI,CSNK1E,FAM169A,PPP6R2,C2CD2L,EXOG,ACOT8,TOM1,POLR1B,FGFR1,CINP,OGA,MALT1,COPS8,GNG4,ATXN2L,IDH3A,KCNH2,MAP4,SLC25A23,PRKAR1B,PRODH,FAM184A,RNASEL,RPS6KA2,SH3BP2,NUBPL,RCOR3,ITPRID2,TMEM121,PLPPR2,SMIM8" Drug 3674_DN Nitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ACTN1,APC,CDK13,CACNA2D2,PLEKHB1,LHX2,HOMER3,CRY2,NCOR2,HDAC9,DAPK3,DMPK,DUSP9,ING4,MRNIP,FGFR1,CSPG5,PCDH17,GLUL,CACFD1,ATXN2L,TJAP1,KCNB1,MAP4,MAPT,TM6SF1,CNOT4,WDR25,RAD51D,ENOX1,GAL3ST4,NEK11,FNDC3A,BTBD7,ARHGAP26,SS18,MCF2L,AMACR,VGF,LAT2,ZNF74,HPS4,PCBP4,KAT6A" Drug 6845_DN Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.91E-06 2.59E-01 1.88E-04 2.11E-03 44 195 "ASPHD1,AP2A2,AK2,LTBP4,AMPD3,CDC42BPA,CDK10,CAMK2G,CACNA2D2,ASIC3,TPP1,CREM,CSF1,SIPA1L1,CTH,RIMS2,PPP6R2,SLC12A6,DTNA,HIPK3,TNK2,FGFR1,FHL1,SEMA4D,GNG4,IL6R,KCNJ5,KITLG,MMP16,CNOT4,PLTP,PRKAR1B,ELOVL2,ZSCAN32,RGS12,RNASEL,CNKSR2,SLC9A5,COA1,ARHGAP26,ARHGEF9,VPS13A,PARD3,PLPPR2" Drug 5208_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.01E-06 2.63E-01 1.91E-04 2.15E-03 43 189 "ADCY6,EPB41L5,MPDZ,BMP7,SCARB1,FOXN3,QKI,ABCG1,MFAP3L,C2CD2L,DTNA,EGR3,ENO2,FGFR3,FAM49B,ZNF44,FERMT2,KCNH2,PCDH9,PIK3R1,SLC25A23,STRN3,LRP12,MBOAT7,PRODH,PTPRE,RXRA,ANKRD6,SMARCC2,ZHX3,ZSWIM8,PHLDB1,TACC1,TNS2,CABIN1,TRIO,SSBP2,ZKSCAN5,UBTF,LMF1,KLC2,UPF3A,EMSY" Drug ctd:C513635 S-2-pentyl-4-pentynoic hydroxamic acid CTD 6.06E-06 2.66E-01 1.92E-04 2.17E-03 137 837 "CLK4,INTS2,NME5,OSBPL6,TXNDC16,APAF1,SFMBT2,ATP1A3,N4BP2L1,RIPK1,SEC11C,CFLAR,BMP7,ST3GAL5,CACNA1B,HAP1,CBLN1,USP2,EVI5L,EPS15L1,NGEF,TMEM184B,GAL3ST1,ABCG1,PHACTR3,GPRASP1,TM9SF4,SCRN1,IP6K1,ARMCX2,C2CD2L,DNM1,GOLT1B,SEZ6L2,KLHL5,RASA4,AASS,EIF5,PCOLCE2,STARD3NL,KATNAL1,REEP2,DLC1,SPSB4,MAD2L2,UBE2E3,SYNCRIP,TMEM107,HVCN1,FUT9,TPPP3,OGA,ACSS1,CYP46A1,RUNDC3A,TXNL4A,SPIN1,TNRC6A,PRDM5,RNFT2,MAP4K5,RASSF8,HBA1,PADI2,NXPH3,FRMD5,ELOVL5,MSL1,NKD1,ZIC5,RBPJ,ITPKA,METTL21A,KCNK3,KCNN1,MAT2A,AQP11,AFF1,N6AMT1,PCBP3,PFKFB2,KCTD15,JAKMIP1,SLC25A23,MAPKAP1,SEPT4,MINDY2,RASGEF1B,PRKACB,CEP41,PRPH,GDPD1,SNRK,ELOVL2,PTPRN,RIPOR1,PPP2R3C,BEND5,ERI2,SGSM1,SALL1,RASA3,FUZ,PEX26,SIRT2,KBTBD4,EPC1,ERC1,SPTAN1,SPTB,ITPRID2,TTBK2,STAC2,ADHFE1,PHLDB1,JMJD6,SYN1,ARC,DMXL2,ZEB1,DOCK9,TNS2,HIF3A,SIRT1,GPR161,TMPO,SYNPO2,PPIL6,TSC2,UBE2H,UCHL1,ZNF24,SLC38A1,SLC17A7,WNK2,AAAS,FRMD6" Drug 6179_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.08E-06 2.67E-01 1.93E-04 2.17E-03 42 183 "NME5,BIN1,APBB2,CDC14B,HIP1R,CHN2,WHRN,PDE4DIP,DAPK3,PARD6A,OPTN,MRNIP,ENO2,LRRC17,TBC1D16,FGFR1,PCYOX1,IQCG,GATM,PCDH17,RAB40B,PCLO,PADI2,FAM69A,KHK,MYO6,PCDH9,SERPINI1,RETREG1,TMEM231,TMEM255A,RPS20,SH3BGR,SMARCD3,ZSWIM8,ELOVL4,RGL1,STXBP1,TRIM2,RPGRIP1L,HEY1,SLC17A7" Drug 6434_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.08E-06 2.67E-01 1.93E-04 2.17E-03 42 183 "MARK4,BMP7,BAIAP3,SPAG9,CLGN,PLEKHB1,WHRN,AKAP12,PDE4DIP,DOCK4,ARMCX2,OPTN,FAM13A,RASGRP2,ACSL4,FYN,CYP46A1,RAB40B,RNFT2,ACOT7,KCNN2,MAP2,NEK1,PCDH9,SERPINI1,PRPH,RPS6KA2,SH3GL3,ASAP3,WDR47,PKNOX2,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug 4710_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.13E-06 2.69E-01 1.94E-04 2.19E-03 41 177 "NME5,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,FAM13A,RASGRP2,BAIAP2,FYN,CYP46A1,GLYR1,RAB40B,STON1,KCNH2,MAP2,MXI1,NEK1,SERPINI1,PRPH,SH3GL3,SYBU,WDR47,CCDC88A,SMARCD3,LIMCH1,SOX15,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,SLC30A3,SLC17A7,ITM2C" Drug CID000000888 magnesium Stitch 6.31E-06 2.76E-01 1.99E-04 2.25E-03 202 1326 "ACTN1,METAP1D,NDRG2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,NME5,AK2,ALK,AMPD2,PHF12,NT5C3B,ARHGDIA,DNAH17,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,KIF1A,BCHE,RGS9,FUBP1,CACNA2D1,CALM1,ARHGEF25,KYAT1,CCK,KRIT1,CCNT1,ENTPD2,ENTPD6,DGKI,LRBA,COPB2,CNOT8,TAOK2,RAB28,MYL6B,RAB26,COL4A5,GAL3ST1,CPS1,ENTPD4,CS,CSNK1E,CSNK1G3,VCAN,DGKB,DGKG,DNAL1,CHRDL1,EXOG,GRIN3A,DNM1,DNAH9,DPYSL2,DTNB,FARSB,DNM1L,AASDH,EDN1,EGFR,HSD17B14,TUBD1,ENO2,GPHN,RAB9B,ERCC2,RASL12,ADGRV1,PTK2B,TUBB3,FDFT1,POLR1B,FGFR1,FGFR3,AK8,TPK1,ATP2C1,FYN,MTHFD2,ACSS1,GCK,TUBA8,HPGDS,RAB30,GLUL,POLL,KCNMB4,GNAL,TPPP,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GSN,LINGO1,GUCY1B1,DDX19B,HMGCR,IDH3A,IDH3B,MYLK2,INPP1,ITGAM,ITPKB,KCND2,KCNH2,KCNJ5,KCNN2,LAMA2,LIG4,MAT2A,MATK,PPM1L,MMP16,MMP17,MYO5A,MYO7A,NBL1,NF1,NME4,NPY,NPR2,OGG1,OPRL1,P2RX7,PDE4B,PDE4D,PDE1B,ENPP2,PFKFB2,PFKFB3,PFKFB4,ABCB1,PIK3C2A,PIK3R1,PKM,PLCB2,PLEC,POLR2F,PPM1B,PPP3CA,PPP3CC,PRKAB2,PRKACB,PRKCB,MAPK10,KLK6,CNNM2,PSMA6,LAMA1,PTK2,PTPRB,QDPR,RAD51D,RNASE1,RNH1,NEK11,RPL15,RYR3,MAPK12,SARS,SMPD3,CASC3,SLA,SLC11A1,SNAP25,SNCA,NMNAT2,ADHFE1,JMJD6,NUDT10,NEU4,SLC19A3,DICER1,TK2,ICAM5,ACTR6,CABIN1,TPM1,NPL,TPM2,SMUG1,NEIL2,TUBB2A,TUBB1,WRN,SPHK2,DPYSL5,PRTFDC1,TUBA1A,GAL3ST3,HRASLS,DNAH10,RTN4" Drug ctd:D020849 Raloxifene Hydrochloride CTD 6.42E-06 2.81E-01 2.03E-04 2.29E-03 140 860 "ADORA2A,AGT,ALCAM,BCAS1,CHRD,NCOA1,DYNLL1,ATP1A1,STX16,ADGRB2,BMP7,SYNJ2,CACNA1I,LDLRAD4,CA4,CA12,CALB2,CALM1,CD86,ENTPD2,CDH2,CDO1,COPB2,CLTB,QKI,NRG2,FAM171B,C2CD2,HAPLN1,NCOR2,ABCG1,AATK,CSF1,LRIG1,OSBPL3,GREB1,RIPOR2,MATR3,PITPNC1,SPOCK3,CDON,TOM1,FIS1,EDN3,EDNRA,PHC2,RASGRP1,EGFR,MBNL2,EGR3,EIF5,EIF1,ENO2,RCAN2,ERBB2,ERBB4,F8,TUBA1B,TAOK3,OLFM1,AMOTL2,FHL1,FLNC,FUT9,GABRG1,TRAF3IP2,GAD1,GDF9,GFRA2,CSDC2,GHR,GLUL,CBX1,ADGRA3,GPER1,GRB10,HAS2,HBA1,ELOVL5,SYNPO,IGF1,IL12A,JAK2,STMN1,MAN2A2,MID1,MN1,ADAM22,NBL1,NCF2,NF1,NPR2,PDE4D,ENPP2,PFKFB3,ABCB1,RETREG1,PMP22,MAPK3,PTPN13,PTPRE,PTPRH,PTX3,RASGRF1,RBBP8,RET,RGS4,RPS6KA2,SAFB,SALL1,SGK1,SYBU,ABLIM3,CDK5RAP3,ATF7IP,RCOR3,LIMCH1,SNCA,SPP1,RGL1,STX1A,ANKRD28,TACC1,TAF9,DNMBP,ZEB1,DOCK9,DICER1,TMPO,CABIN1,TPM1,SSBP2,SGK3,XPO1,NDRG4,SEMA3B,SLC17A7,ADAMTSL3,NLRP3,SPATA13" Drug ctd:D008558 Melphalan CTD 6.63E-06 2.91E-01 2.08E-04 2.34E-03 57 278 "MTA3,HECW2,CC2D2A,ARHGAP20,CDC14B,RASL11B,BCHE,DST,LURAP1,KALRN,RUNX1T1,ZNF521,NRG2,SOCS5,RIPOR2,ARHGAP24,EBF1,SNX29,EDN1,FRY,EMX2,MEX3B,NOP56,PDLIM5,RASL10A,DBF4,PRUNE2,FUT10,GRIN2C,IL12A,JAK2,KITLG,MITF,PIK3R1,PPP2R2B,MAPK3,PTPRG,FAT4,ENOX1,RADX,REV3L,FIGN,ZFHX4,SEMA6D,SCN8A,TNFRSF19,SGK1,SLC14A1,TET1,TRERF1,SPATA7,RGL1,ANKRD28,MTCL1,KIAA1107,TLR4,RGMB" Drug 4434_UP alpha-estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADORA1,AQP6,ZSCAN18,N4BP2L1,KIF1A,HAP1,CBS,CHN2,TAOK2,TPP1,NCOR2,SPOCK2,C2CD2L,SPOCK3,DTNA,EDN3,EPHB1,KAT8,BAIAP2,ERAP1,SIGLEC8,ALDH1L1,SRCAP,GPR75,LPAR4,GSTM5,HLF,RETREG1,PURG,POU6F1,RNASEL,KLHDC8A,ZNF821,STUM,PPM1E,NLGN1,SLC2A5,PKNOX2,SLC6A11,VPS13A,CRTC1,ZFPM2,ZNF154,SLC17A7" Drug 5989_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ATP2B2,FUBP1,SCAPER,CD86,CACNA2D2,CHGB,CHN2,WHRN,DGKG,KLHL3,DMPK,C3orf18,COQ7,MTSS1L,ZNF391,ST3GAL6,GCNT2,GFER,GNAL,GPD2,ATXN2L,TJAP1,KCNJ5,KIF2A,LAMA2,MEF2C,NOVA2,PCDHGC3,DUSP26,SERPINI1,PLCD1,KCTD17,DCUN1D2,TCP11L1,ZNF821,SH3BP2,SH3GL3,PKNOX2,RBM34,KDM4C,PLCB1,DOCK9,UBE3A,HRASLS" Drug 6301_UP Clopamide [636-54-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADD2,C1QTNF3,LTBP4,PKP4,PTCH2,N4BP2L1,GYG2,CACNA2D1,CAMK2A,ARHGEF2,ARMC8,VCAN,PDE4DIP,DCAF8,PLXNC1,COQ7,RASGRP2,STX2,APC2,ZNF589,PDLIM5,DLL3,DENND2A,GAD1,STON1,CNTRL,ATXN2L,IL6ST,TM6SF1,MX1,KCTD15,CNNM2,PTCH1,PTPRN2,RGS12,SCN2B,STUM,CCDC88A,SLC11A1,FAIM2,ARHGEF9,KIAA1107,CHST8,R3HDM1" Drug 4182_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AMPD3,APBA2,GAS7,DNAH17,ALDH7A1,CFAP410,SLC16A4,CRLF1,FOXN3,SNCAIP,CSF1,DAPK3,SPOCK2,TMCC2,CDON,FEM1B,ERCC2,DLC1,ZNF589,FHL1,KHDRBS3,SEPT9,LYVE1,TXNL4A,RAB30,FERMT2,KCNN1,KCNQ3,SMAD1,MAPT,ADAM22,NNAT,PPP2R2B,SLC9A5,SMARCD3,SNAP25,ZHX3,ZC3H13,ARC,SYT5,WSCD1,TRO,TRPM2,PLSCR4" Drug 3029_UP Dimethadione [695-53-4]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "DDO,SLC2A11,MPDZ,RGS11,BMP7,CFAP410,KALRN,RUNX1T1,USP2,CHGB,LHX2,RIMS2,EDN3,PLXNC1,ETV1,ANKMY1,F5,OLFM1,FGFR3,FHL1,GFER,ZNF276,MCHR1,PCLO,AP4S1,MAPT,MATN2,AFDN,ADAM22,NELL2,ABCB1,POU6F1,MAPK7,RPS20,CXXC4,DOK5,CLSTN2,ARC,WSCD1,PCDHGB6,PHF24,AP4E1,KCNK12,JPH3" Drug 5405_UP Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AK2,CDC14B,SEMA4G,CAMK2G,QKI,CNTN1,MYEF2,RUSC2,DTNA,EGR3,PCOLCE2,FECH,PDLIM5,USP19,PCDH17,RAB30,GNAL,GSTM5,RASSF8,ICA1,JAK2,ADAM11,AFF1,MYO7A,NNAT,PLCD1,SMOX,PPARA,RET,RFX2,SALL1,SYBU,SLC2A5,SMARCD3,SNCA,DOK5,ARC,ANKRD12,PDLIM2,TBCEL,TIAM1,BCL2L13,GDPD5,SEMA3B" Drug 6624_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "BIN1,APAF1,KCNAB2,ADAM15,ADGRB2,CFLAR,SYNJ1,FUBP1,ARHGEF2,PLEKHB1,TPP1,CNTN1,AKAP5,RCHY1,CRY2,CYBB,HIPK3,MBNL2,ING4,ETV1,VPS26C,ZNF589,FGF1,FGFR1,HPCAL4,GPER1,GRM2,KITLG,NTRK2,PFKFB2,PFKFB4,CEP41,ELOVL2,KCTD17,RYR3,STUM,ASAP3,HKDC1,PPP4R3A,SLC6A11,ZC3H13,PHLDB1,SMUG1,ZNF74" Drug 2645_DN Droperidol [548-73-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "DOC2A,CDC42BPA,APBB2,CDC14B,BCL7A,BMP7,ST3GAL5,CFAP410,QKI,CDC42BPB,SIPA1L1,DCAF8,DTNA,CDKL3,FER,FGFR3,AGAP2,ANKFY1,ERAP1,INPP5K,HNMT,DHX35,KHK,MAP4,NF1,ZDHHC14,EMID1,SBF1,AMBRA1,PEX26,KDM4B,SOX3,ZHX3,TSPYL2,ARHGEF9,VPS13A,TACC1,ANKRD12,EXOC7,IQCE,KIAA0930,ZNF34,PLPPR2,HPS4" Drug 2280_DN Ethosuximide [77-67-8]; Down 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "C1QTNF3,APBA2,APBB2,GAS7,APOC1,PLA2G4C,MARK4,NUMB,RASL11B,CFLAR,CFAP410,ARHGEF2,HOMER3,RIMS2,DTNA,EGFR,PLXNC1,FGF12,FHL1,GCNT2,SRCAP,POLL,GRIK5,CACFD1,KITLG,MMP16,NPR2,CDK18,RETREG1,KLHDC8A,SBF1,ZNF821,SH3BP2,SYBU,PEX26,SLC22A4,LIMCH1,SPART,TROVE2,STX1A,ARC,TRIM2,PLPPR2,HPS4" Drug 7335_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ABHD6,NDRG2,C1QTNF3,SRPX,LTBP4,APBB2,SLC2A11,CFLAR,RAB29,USP2,SRSF11,QKI,HOMER3,ARHGEF6,GREB1,SNPH,GIT2,RUSC2,MBNL2,PLXNC1,MTSS1L,STX2,ERCC2,PRELID3A,SIGLEC8,SRCAP,TXNL4A,TDRKH,GRIK5,ELOVL5,DHX35,IL6ST,KIF5A,MITF,NF1,NLE1,SLC25A23,RFX2,RGS12,FBXW7,TRAPPC13,DMXL2,SLC17A7,JPH3" Drug 2687_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "NDRG2,MTUS1,CDC42BPA,PKP4,MPDZ,CACNA1A,QKI,ENTPD4,NCOR2,VCAN,CTH,CNNM1,MRNIP,VPS26C,FGFR1,INPP5K,RUNDC3A,GPD2,GRB10,MAP4K5,PADI2,ATXN2L,ITGA7,LIG4,MAP4,PDE4A,PPARA,CLIP1,ZFP30,FAM102A,NLGN1,EPN2,SLC6A8,SLC11A1,COA1,UNC5B,ARHGAP26,KANK1,THRA,TPM1,CDK20,SSBP2,FLRT2,XRCC4" Drug 1184_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "APOC1,ARNTL,PDE8B,MTMR3,CACNA1A,CD86,CBFA2T2,CREM,DBT,RUSC2,GSDME,HIPK3,FAM13A,MBNL2,PLEKHA1,ING4,RASGRP2,F5,ANKFY1,INPP5K,AHDC1,GLYR1,POLL,MEF2C,MPP2,MX1,P2RX7,MINDY2,MRPS18A,RPS6KA2,TRAPPC13,GALNT10,ASAP3,SLC11A1,IQSEC2,LHPP,ZC4H2,CEP68,STXBP1,PLCB1,KIAA1107,TNS1,NPDC1,GAN" Drug 3473_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AK2,C1QTNF3,LTBP4,GAS7,ATP6V0A1,CFLAR,SYNJ1,SYNJ2,MTMR3,HIP1R,ENTPD4,ABCG1,CSF1R,GREB1,DCAF8,MAML1,PLEKHA1,VPS13B,FGFR1,IQCG,ZNF44,GLYR1,IL6ST,INPP5B,MATK,AFDN,MPP2,ADAM22,PCDH9,MINDY2,ELOVL2,ZDHHC14,GSTCD,CLIP1,SUPT20H,SH3BP2,COA1,SMARCD3,ZHX3,SPTAN1,EXOC7,KIAA0930,DICER1,REEP1" Drug 3972_DN Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADORA2A,NME5,AMPD3,EPB41L5,GAS7,SEMA4G,CACNA1A,USP2,SLC16A4,CBFA2T2,SCARB1,ARHGEF2,CLGN,CPS1,CSF1,PDE4DIP,RIMS2,CYBB,MFAP3L,CDON,EDN1,EDNRA,ING4,VPS13B,FGFR1,KHDRBS3,GPER1,ADAMTS13,BTN2A1,GSN,KCNN1,KHK,ADAM22,MTRF1L,LRP12,TRIM68,SEMA6D,PREX2,ARHGAP26,VPS13A,VIPR2,ZFP37,SLC17A7,PLSCR4" Drug 5461_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADRA1B,ALCAM,RGS20,BAIAP3,LDLRAD4,SLC16A4,CACNA2D2,ARHGEF4,RIMS2,DCAF4,DBN1,DTNA,ING4,MRNIP,C3orf18,SPEG,ZNF589,FGFR1,HPCAL4,NEU3,GFER,HPGDS,GLYR1,ATXN2L,ICA1,MAP4,ADAM22,NF1,MINDY2,MAPK7,PTPRD,PTPRO,RGS12,CCDC25,FBXW7,SALL1,ST6GAL1,ANKRD6,FAM214B,ARHGEF40,ZHX3,ZSWIM8,KDM4C,HPS4" Drug 4619_DN Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADRB2,AMT,APBB2,STX16,ADGRB2,SCAPER,CACNA1I,SYNGR3,PLEKHB1,SLC4A8,FAM131B,SGSM2,FEM1B,EGFR,DLC1,FER,AFF2,B4GALNT1,SIGLEC8,GCNT2,CACFD1,FAM69A,LIG4,MAPT,MT1M,MX1,PDE1C,PPARA,PRPH,CNTLN,PTPRB,ZSCAN2,RGS3,FBXW7,ASAP3,SLA,SNCA,TSNAXIP1,IQSEC2,ZBTB43,CHST8,XRCC4,ZNF711,NAV3" Drug 6435_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "LTBP4,FAM131A,PROM1,BAIAP3,CALB1,SCARB1,ARHGEF2,PLEKHB1,RAB33A,HOMER3,VCAN,FGFR1,TMEM8B,ADAM28,POLL,GRB10,ACOT7,L1CAM,MEIS2,PFKFB2,RELN,PTPRE,PTX3,ENOX1,RPS6KA2,RYR3,SATB1,ATXN7,CXXC4,SNCA,FAIM2,KDM4B,SOX11,DOK5,ATP10B,PHLDB1,TBL1X,SYNE1,RUNDC3B,SPHK2,ADAMTS9,KCNAB1,PLSCR4,RNF146" Drug 2793_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADORA1,ADORA2A,SPARCL1,BIN1,KCNAB2,CFLAR,SYNJ2,CACNA1I,CACNA2D2,RCBTB2,ASIC3,TAOK2,COL9A3,CNTNAP2,DCAF4,GIT2,HIPK3,HSD17B14,PDLIM5,USP19,GSTM5,ICA1,IL6R,CCSER2,PLTP,RETREG2,MINDY2,C1orf54,ZDHHC14,RFX2,RGS3,RGS12,RPS6KA2,ASAP3,SYBU,SMARCD3,TSPYL2,ST5,TRIM2,CABIN1,NDRG4,SEMA3B,KAT6A,AP3B2" Drug 6038_DN Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ABHD6,AP2A2,ALCAM,LTBP4,BIN1,APC,PPFIA3,CDC14B,ARHGDIG,ADAM15,CACNA1I,CBFA2T2,TAOK2,HOMER3,CREM,CSF1,PDE4DIP,GPRASP1,DCAF8,SGSM2,EIF5,ERBB2,KAT8,FHL1,SEMA4D,ADAM22,CNOT4,CCSER2,PRKAR1B,PRPH,CEP97,RNASEL,SEC14L1,ZNF821,COA1,TACC1,IQCE,NPL,VGF,LMF1,XRCC4,ZNF74,GDPD5,HPS4" Drug 4685_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AMT,PPFIA4,APOC1,SLC4A4,FUBP1,CACNA1G,LDLRAD4,CRLF1,NRXN3,ABCG2,SH2B1,PDE4DIP,BRINP1,MFAP3L,EDN1,EIF4G2,ING4,MTSS1L,FAM198B,ST3GAL6,SRCAP,KCNMB4,TJAP1,MMP16,NF1,PDE4B,ZSCAN32,TMEM231,RGS4,FRMPD1,DZIP1,BTBD7,SNCA,LHPP,SZT2,DOCK9,AP4E1,TIMP4,TNS1,RPRM,SEMA3B,MPPE1,FAM13C,KAT6A" Drug 5673_UP Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "NDRG2,ADRA1D,C1QTNF3,ABCD2,ALK,FGD2,CACNA1G,CAMK2A,RAB33A,STOML1,QKI,BRINP1,DBT,DUSP9,ERCC2,NCALD,ZNF589,MSTN,LYVE1,GLI2,GNAL,PRUNE2,GRIK5,GSN,ATXN2L,KCND2,MGAT3,MN1,MSR1,NCF2,PCBP3,PLCD1,MTRF1L,PILRA,TRIM68,SH3BP2,SNCA,DOP1A,UNC5B,KIAA1107,SLC19A3,ZFPM2,MKRN3,NT5M" Drug 2431_DN Melatonin [73-31-4]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "RALGAPA1,BIN1,PPFIA4,APAF1,SCAPER,LDLRAD4,CAPN3,CCNT1,ARHGEF1,RAB33A,ARMC8,CREM,CRY2,ABCG1,CSNK1E,SLITRK5,DTNA,CELSR3,C3orf18,INPP5K,ALDH1L1,SPACA9,NCKAP1L,MAP4,MYO7A,CNOT4,NPR2,CNTLN,PTCH1,TMEM231,CEP97,ZCWPW1,MRAS,SH3BP2,ZKSCAN3,SNCA,IZUMO4,ADGRL3,CHST8,ICAM5,PIK3R5,HSPBP1,LMF1,SPHK2" Drug 4491_DN Althiazide [5588-16-9]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ASIC1,AK2,ALK,KCNAB2,APC,SLC4A4,SCAPER,MYRF,IL33,SCARB1,ARHGAP33,IQCK,ARMC8,SLC4A8,CSNK1E,RUSC2,EDNRA,EGFR,SPEG,CDKL3,ETV1,ANKMY1,FYN,TRAF3IP2,DENND2A,KCNMB4,GPR37,SHISAL1,KCNJ5,LSS,MEF2C,PTCH1,ZCWPW1,ZDHHC14,ZNF821,OGDHL,SMARCD3,SPTAN1,R3HDM1,TNS1,TPM2,ZNF711,ZNF24,DPF3" Drug 2811_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ABHD6,CDC42BPA,APOC1,ARHGDIG,ATP6V0A1,CFLAR,SCAPER,AKAP7,CLOCK,CRY2,LYPD1,FGFR3,BAIAP2,TRMO,SRCAP,TXNL4A,MUM1,HNMT,AGFG1,DHX35,INPP5B,JAK2,KCNH2,KPNA5,LSS,MAP4,MITF,ADAM22,ZNF862,NACA,NEK1,SLC25A23,PRPH,TMEM104,ELOVL2,ZNF331,AMBRA1,EPN2,SP2,CAMTA2,TBL1X,NDRG4,HPS4,ACTR3B" Drug 1512_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AK2,OGT,FAM131A,SLC4A4,CFLAR,SRSF11,RAB28,ARMC8,ZNF337,FBXL5,C2CD2L,RCAN1,FEM1B,EZH1,FER,SEMA4D,GLYR1,CNTRL,DIDO1,RNFT2,LIG4,MBNL1,MPP2,NLE1,STRN3,LRP12,WDR25,TCP11L1,SEC14L1,ZNF821,FBXO11,UNC5B,CLSTN2,ELOVL4,ARHGEF9,PLCB1,EXOC7,IQCE,METTL3,SSBP2,REEP1,SEMA3B,SMIM8,PHTF2" Drug 4361_UP Flutamide [13311-84-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "LTBP4,APC,AQP6,CHRD,N4BP2L1,CACNA1G,CDH2,DLGAP1,SIPA1L1,VCAN,DGKG,DAPK1,SPOCK2,DBT,RCAN1,AASS,RASGRP2,ERBB2,FGF12,EFCAB2,SIGLEC8,RUNDC3A,GRIK5,KCNJ5,KCNN1,NPY,NOVA2,PLCD1,PRKCB,RELN,GAL3ST4,RNASE1,SLC11A1,HECW1,ATP10B,TAL1,RPGRIP1L,FAM189A1,HEY1,PARD3,UCHL1,WIPF1,LAT2,ZNF24" Drug 4750_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "RALGAPA1,ASIC1,ADORA1,ADGRF5,SEMA7A,CDK13,CFAP410,ARHGEF1,VAX2,CPS1,AATK,SNCAIP,DRP2,DTNB,EDN3,PLXNC1,C3orf18,RASGRP2,ERCC2,IGSF6,FGFR1,FHL1,CAMKK2,OGA,FYB1,ALDH1L1,SRCAP,GPR75,GNAL,PCLO,TJAP1,ADAM22,MYT1,P2RY1,PALM,PLCB2,PLTP,MAPK7,C1orf54,TCP11L1,ASAP3,CNKSR2,SPART,THRA" Drug 4551_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "LTBP4,BEGAIN,CDK13,PTCH2,ST3GAL5,KALRN,CCNT1,SCARB1,ENTPD4,NCOR2,CSF1R,VCAN,MFAP3L,SPOCK3,DTNB,CNNM1,CELSR3,ETV1,ZNF589,FGF1,AFF2,DCTN2,OGA,ELOVL5,KCNN1,NF1,NOVA2,GRAMD1C,PTPRH,PTPRN2,MARCH1,CCDC40,RGS12,TCP11L1,RASA3,AMBRA1,PREX2,KIF13A,DOP1A,ZHX3,ARHGAP26,TCF4,TPM1,SSBP2" Drug 5270_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "NDRG2,APBA2,APC,CDK10,ARHGDIG,PDE8B,CFAP410,CPS1,PDE4DIP,GIT2,EXOG,DNM1,DTNA,HIPK3,MBNL2,EPB41L2,COQ7,PIPOX,EZH1,FGFR1,GALC,MALT1,GPD2,STON1,GPER1,PCLO,CACFD1,IPO5,MAP4,ADAM22,ZNF862,SETD4,P2RY1,PLEC,PPP2R2B,RIPOR1,CARF,SH3BGR,CXXC4,SNCA,ARC,SLC44A1,ZKSCAN5,KLC2" Drug 7027_DN (-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ABHD6,NDRG2,APC,APOC1,PPFIA3,CBFA2T2,NCOR1,ABCG1,DZIP3,CTH,PPP6R2,C2CD2L,LYPD1,MED12,APH1A,RGS17,STX2,EXTL2,SEPT9,MSL3,RNFT2,NF1,STRN3,MBOAT7,PRKAR1B,TMEM104,PTPRG,MAPK12,SH3BP2,DOP1A,ZHX3,SPTAN1,CDK19,ZBTB43,CEP68,ANKRD12,MCF2L,NSD1,PCDHA6,TMEM121,TFIP11,GDPD5,TIGD6,AAAS" Drug 6483_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADRA1D,AK2,SEMA6A,AMH,CDC42BPA,APC,FAM131A,DNAH17,MARK4,BAIAP3,CAMK2B,SCARB1,CRY2,GREB1,EDNRA,FAM49B,OGA,GCNT2,POLL,PRUNE2,INPP5B,P2RY1,POLG,PTN,ZSCAN32,PTPRO,KHDRBS2,ATXN2,ZNF821,NLGN1,SLC9A5,INTS9,DOK5,ZHX3,IQSEC2,SS18,ARC,EXOC7,TRIM2,TNS2,ZKSCAN5,HIRA,KCNK12,ZNF74" Drug 5734_DN Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADD2,AP2A2,NME5,APBA2,SEMA4G,SCAPER,CHN2,SULT4A1,CSF1,DCAF8,GIT2,MFAP3L,EZH1,TRAF3IP2,ERAP1,ZNF276,GNG4,FERMT2,CNTRL,IL12A,MAPT,TM6SF1,NF1,CNOT4,SERPINI1,NLE1,FSD1,MAPK7,PTPRN2,GAL3ST4,RPS6KA2,AMBRA1,KBTBD4,SMARCD3,SNCA,KDM4C,ARHGAP26,SS18,PHLDB1,TCF4,HIRA,VGF,LMF1,KLC2" Drug 5765_DN Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "APOC1,SEMA4G,ALDH7A1,SYNJ2,LRRFIP1,AKAP7,NCOR1,CSF1,CSF1R,PDE4DIP,SLITRK5,GIT2,TMCC2,TOM1,EDNRA,MRNIP,SPEG,DENND2A,GLUL,SHISAL1,TJAP1,MT1M,ZNF862,NF1,OGG1,CLDN11,PCDH9,MAPK7,SNRK,PTPRN2,ZNF821,AMBRA1,ZHX3,KDM4C,THSD1,COBL,EXOC7,KIAA0930,CRTC1,GPR161,LMF1,WNT7A,ZBTB14,NT5M" Drug 6655_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADRA1D,AP2A2,FAM135A,SEMA7A,KCNAB2,APBB2,APC,ATP2B2,RGS11,CFLAR,CALB2,HIP1R,CRY2,ARHGEF10,SV2B,DUSP9,SEMA3D,ING4,EPHB1,STX2,IGSF6,F5,KAT8,POLR1B,AFF2,PDLIM5,ADAM28,PCDH17,GLI2,KCNJ5,AFDN,OPRL1,PDE4D,DCHS2,ZSCAN32,NKAIN1,RASA3,SLA,SLC11A1,SNCA,PCDHA5,FLRT2,SPHK2,REEP1" Drug 4965_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "TRMT9B,BIN1,FAM131A,RASL11B,ALDH7A1,KIF1A,CACNA1I,CACNA1G,BAIAP3,ARHGEF1,ARHGAP33,CACNA2D2,HOMER3,ARMC8,CSF1,CSF1R,GREB1,PIPOX,FHL1,SEMA4D,SRCAP,USP19,GSN,KCNQ3,KIF5A,ADAM22,RETREG1,MAPK10,PRPH,ZSCAN2,ZNF493,RGS12,KIF13A,ZC3H13,ZBTB43,ATP10B,ELOVL4,PHLDB1,TBCEL,PARD3,TRIO,KCNK12,AP3B2,SENP7" Drug 2254_UP Etodolac [41340-25-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "SYN3,AMH,AMPD3,GAS7,CDK13,BAIAP3,KCNAB3,RCHY1,CPS1,CREM,NCOR2,VCAN,FAM169A,DAPK1,RUSC2,GSDME,HIPK3,CNNM1,HEYL,PTK2B,OGA,ADAM28,GPR75,DHX35,C2orf72,ITGAM,KCNJ5,MAP2,LRP12,PTCH1,PTPRN2,CCDC40,C1orf54,RPS6KA2,RTN1,SCN2B,ZNF821,PKNOX2,COA1,CDK19,SMG6,TCF4,SLC35G2,TUBB1" Drug 6364_UP CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADORA1,NME5,KIAA1324,AMPD3,APBA2,ARRB1,PDE8B,DNAH17,SLC4A4,GYG2,CD38,STOML1,FAM149A,AATK,CSF1,CSF1R,RGS6,RIMS2,SEC14L5,DTNB,SEMA3D,SPEG,NSG1,SEPT9,GLYR1,KCNMB4,GNAO1,GRM2,KIFC3,TREM2,PLCB2,LRP12,ACSM5,ZFHX4,FNDC3A,SLC11A1,SNCA,IZUMO4,MCF2L2,RGL1,TCF4,CHST5,LAT2,FAM13C" Drug 2877_UP DO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ALK,FAM131A,RGS20,PLA2G4C,DNAH17,RGS11,CFLAR,BAIAP3,CBFA2T2,FOXN3,CHRNA4,PICK1,SPOCK2,HSD17B14,EPHB1,ERBB2,F5,KHDRBS3,NSG1,HPGDS,SOX21,IRF8,MID1,NNAT,P2RY1,PCSK1,PFKFB2,PURG,LRP12,CEP41,VPS13C,ZNF493,RPS6KA2,ASAP3,SLC9A5,ZNF423,ASTN2,SLC19A3,R3HDM1,TNS1,PDIA2,FLRT2,ZFP37,KCNAB1" Drug 1545_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "NDRG2,SPARCL1,AMPD3,AMT,APOC1,MARK4,CFLAR,SYNJ2,CBFA2T2,ARHGAP33,CLGN,CACNA2D2,AKAP7,RIMS2,FRY,ING4,ERCC2,ZNF589,RUNDC3A,HNMT,C2orf72,KIT,LIG4,AFDN,CEP41,CCDC40,CARF,CNKSR2,SYBU,SLC11A1,SNCA,RBM34,ERC1,SPTB,SYN2,KIAA1107,TRIM2,SZT2,GPR161,TIAM1,TK2,PIK3R5,WIPF1,SENP7" Drug 4482_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ALK,AMPD3,APC,BCAS1,PPP4R4,ATP1A3,NRP2,CFLAR,GYG2,CAMK2B,PLEKHB1,EPS15L1,STOML1,HOMER3,PICK1,NCOR2,FAM131B,EDNRB,LRRC17,ALDH1L1,CACFD1,KCNH2,MAN2A2,NPTX2,PALM,PDE4A,GPR85,PFKFB2,SNRK,ZSCAN32,PTPRH,FAT4,TCP11L1,CNKSR2,ARHGEF40,ZHX3,AP4E1,TNS1,CHST5,ZKSCAN5,FLRT2,VAV1,SPHK2,KCNAB1" Drug 2737_DN Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ABHD6,AP2A2,CDC42BPA,APAF1,FUBP1,CACNA1A,QKI,HOMER3,CREM,DAPK3,DBT,FCF1,ING4,TUBD1,COQ7,RRAGB,ZNF589,PRKAG2,PDLIM5,CAMKK2,ZNF276,GPD2,LILRA2,PADI2,INPP1,MAP4,CNOT4,PDE4A,CCSER2,PLEC,PTCH1,ZSCAN32,TMEM231,CEP97,ZNF821,RGL1,STX1A,NSFL1C,CRTC1,ZNF34,KAT6B,TRPS1,SSBP2,ZNF225" Drug 7055_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AP2A2,SEMA6A,LTBP4,DOC2A,APBB2,ARHGDIG,BCL7A,BMP7,SGCE,CA12,FOXN3,USP6NL,LYPD1,HSD17B14,BAIAP2,FAM49B,DISC1,GPD2,STON1,GPER1,CACFD1,ATXN2L,MAP4,MITF,MMP16,CLDN11,PCDH9,MINDY2,CEP97,RGS3,TCP11L1,EMID1,MAPK12,SH3BP2,MAPKBP1,DOP1A,KDM4C,ARHGAP26,IQSEC2,PHLDB1,TMPO,TSC2,VIPR2,VSNL1" Drug 5758_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "SEMA7A,PRX,ATP2B2,ST3GAL5,BAIAP3,CAMK2A,SYNGR3,DLGAP2,PLEKHB1,COL9A3,CREM,ABCG1,CSF1,C2CD2L,DNAH9,EDNRB,CELSR3,PLXNC1,HPCAL4,SYT17,PRUNE2,GRIK5,TJAP1,JAK2,KHK,AFDN,PFKFB2,PLXNB1,C19orf57,LRRN3,ZSCAN32,PTPRD,KHDRBS2,SH3BP2,SLC8A1,SLC11A1,ZC3H13,TAL1,DOCK9,PCDHA6,SLC44A1,AMACR,RPRM,SLC17A7" Drug 7400_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADGRF5,SYT13,SEMA7A,GAS7,APOC1,DNAH17,BAIAP3,FOXN3,CHN2,TAOK2,WHRN,SLC4A8,NCOR2,MFAP3L,RUSC2,EDN1,RASGRP2,OGA,ERAP1,SRCAP,ZNF276,LPAR4,SHISAL1,IL12A,KCNJ5,MATN3,AFDN,CLDN11,FBXW7,TRAPPC13,MAPK12,SUPT20H,FBXO11,NLGN1,KIF13A,TSNAXIP1,TAL1,AP4E1,SSBP2,ZKSCAN5,VIPR2,XRCC4,UBE3B,DPF3" Drug 4358_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "ADCY6,ALK,CDC42BPA,APBA2,APBB2,APOC1,MARK4,RIPK1,BCL7A,GYG2,CA12,CAMK2G,ARHGAP33,LHX2,CNTFR,CNTNAP2,MAML1,MFAP3L,HIPK3,VPS13B,GALC,GRIK5,DHX35,IL6R,KCNH2,MMP16,NF1,NTRK2,NLE1,MAPK7,CCDC40,ZFHX4,RASA3,SH3BP2,SMARCC2,DOP1A,ARHGAP26,VPS13A,PLCB1,KIAA1107,TMEM121,CDK20,RUNDC3B,SMIM8" Drug 7506_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.79E-06 2.98E-01 2.08E-04 2.34E-03 44 196 "AP2A2,BIN1,APC,KIF1A,MTMR2,C5,CA12,SLC25A14,TAOK2,CNTFR,ABCG1,CSF1R,SOCS5,DMPK,DTNA,SUGP2,FGF12,PRKAG2,GRB10,HNMT,ITPKB,MITF,AFDN,MYCN,NFYA,OCRL,SLC25A23,MBOAT7,TMEM231,RAD51D,ZDHHC14,EMID1,ZNF821,ZFP30,SLC6A8,THSD1,COBL,SMG6,ZNF34,ZKSCAN5,FAM155A,VAV1,ZBTB14,EVI5" Drug 7546_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-06 3.03E-01 2.11E-04 2.37E-03 43 190 "BRAP,SEMA4G,SLC4A4,MPDZ,PICK1,AKAP7,WHRN,CREM,AKAP12,CRY2,ABCG1,CTH,FEM1B,FAM13A,STX2,CDKL3,ETV1,FYB1,GSN,INPP5B,ITPKA,LIG4,MMP16,PDE4D,SMOX,PRKAR1B,SAMD9,PTN,PTPRE,TRAPPC13,ASAP3,MYH15,ARHGAP26,SS18,SYT1,ASTN2,SZT2,TIAM1,TFIP11,EMSY,HPS4,SEMA3B,PCBP4" Drug CID006436102 NF T Stitch 6.92E-06 3.03E-01 2.11E-04 2.37E-03 43 190 "ACHE,APBB2,APLP1,APOC1,ATP6V0A1,BCHE,CA4,RUNX1T1,CNR1,DPYSL2,TUBD1,TUBB3,FCGRT,FKTN,CELF1,TUBA8,CYP46A1,POLL,MAP2,MAPT,MBNL1,NEFM,NEFH,PLCD1,KANSL1,MAPK3,MAPK9,RELN,SNCA,DDN,PLCB1,SYN1,ARC,SYN2,SYP,TUBB2A,TUBB1,UBC,ZIC1,TUBA1A,HPS4,FXR1,NETO1" Drug 5579_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.92E-06 3.03E-01 2.11E-04 2.37E-03 43 190 "OSBPL1A,BIN1,DNAH17,MPDZ,CFLAR,GYG2,QKI,NECTIN3,AATK,SPOCK2,MFAP3L,DTNA,EDN1,EDNRA,C3orf18,AMOTL2,AFF2,FYN,DISC1,SRCAP,HLF,IL6R,AFDN,MN1,NINJ2,P2RY1,CDK18,KLK6,ENOX1,HSPA4L,SH3BGR,KANSL3,CCDC88A,ZNF334,ZNF423,WSCD1,ZEB1,TRIM2,PCDHGA10,DICER1,UCHL1,SLC30A3,FXR1" Drug 7145_DN Nocodazole [31430-18-9]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-06 3.03E-01 2.11E-04 2.37E-03 43 190 "APBB2,SYNJ2,TBRG4,RCBTB2,AKAP7,USP6NL,KIAA0753,KLHL3,RHOBTB1,EGFR,STX2,VPS26C,NBEA,FAM49B,GCNT2,GUCY1B1,HAS2,ITPKB,TAGLN3,NEK1,PCDH9,SERPINI1,PIK3R1,CCSER2,PID1,ATXN7,ABLIM3,PEX26,ZKSCAN3,SPATA7,ARHGAP26,SS18,TTBK2,RGL1,ARHGEF9,SIN3B,HEY1,SSBP2,NPDC1,XRCC4,ZBTB14,TRIM9,KAT6A" Drug 6895_UP 0297417-0002B [362658-29-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-06 3.03E-01 2.11E-04 2.37E-03 43 190 "NME5,APBB2,CDK13,BACH1,IL33,SYNGR3,CRLF1,CACNA2D2,AKAP7,COL9A3,CSF1,TBC1D5,SGSM2,ECM2,FCF1,OPTN,YAF2,OGA,SEPT9,SRCAP,GNAL,SOX21,ITGA7,JAK2,KCNQ3,LSS,AFDN,MYO6,NEK1,CDK18,PDE4B,PDE4D,PFKFB2,RAD51D,CLIP1,TRAPPC13,FNDC3A,DZIP1,SOX15,TACR1,KIAA1107,ZBTB14,RNF146" Drug CID006419759 K00077 Stitch 6.94E-06 3.04E-01 2.11E-04 2.38E-03 48 221 "ADORA2A,ADRA1B,DDR1,CALM1,KRIT1,LRBA,CDC25B,CNTFR,AKAP5,NRG2,CRY2,EGFR,EIF1,ERBB4,PTK2B,PPP1R1B,FGF1,SEMA4D,GFRA2,STMN2,MYLK2,NIM1K,IL6ST,KCNJ5,LIFR,MBP,MEF2C,NTRK2,NTRK3,PDPK1,PIK3C2A,PIK3R1,PLXNB1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTK2,RET,CDK5RAP2,NFASC,TAL1,TPM1,TPM2,VGF" Drug 4483_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.10E-06 3.11E-01 2.16E-04 2.43E-03 41 178 "ASPHD1,MARK4,ST3GAL5,USP2,CHN2,NRXN3,WHRN,ABCG1,ARHGEF10,PDE4DIP,CTH,C2CD2L,PTK2B,TAOK3,BAIAP2,PDLIM5,FYN,ZNF44,GUCY1B1,ITGA7,LIFR,LSS,MAP2,MAPT,PCDH9,SERPINI1,RETREG1,PTPRH,ENOX1,RGS4,FAM102A,SH3GL3,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,KIAA0930,TNS1,SLC17A7" Drug CID002733618 Frie Mao 1-43 Stitch 7.24E-06 3.18E-01 2.20E-04 2.48E-03 20 61 "AMPH,RHBDL1,CLTC,SNAP91,STX2,ADGRV1,GRM2,GRM8,CIT,MAP4,MYO5A,MYO7A,P2RX7,PRPH,SNAP25,STX1A,SYN2,SYP,SYT1,SLC17A7" Drug 6642_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG2,APBB2,CDC14B,CDK10,KIF1A,BMP7,LARGE1,DLGAP1,CHRNA4,NCOR2,CSF1,RGS6,DMPK,MRNIP,OLFM1,AFF2,ERGIC3,NSG1,NEU3,RUNDC3A,TOX3,POLL,GNAO1,SPACA9,VSIG4,HNF4G,KCNJ5,PACRG,AFDN,ENPP2,RETREG1,PPP1R1A,LRRN3,ZSCAN2,ACSS3,RASGRF1,ZFP2,SLA,SNCA,VIPR2,REEP1,SLC30A4,NT5M,DNALI1" Drug 1541_DN Chlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADD1,CDC42BPA,EPB41L5,GAS7,ARRB1,SLC4A4,CFLAR,ST3GAL5,CBFA2T2,UBE2L6,CLCN3,SULT4A1,DCAF8,LYPD1,TMCC2,TOM1,MBNL2,DENND4A,ZNF589,FAM49B,OGA,AHDC1,IPO5,MIA2,NF1,CNOT4,RETREG1,NLE1,PRKAR1B,TCP11L1,ZNF821,EPN2,BTBD7,KDM4B,ELOVL4,PRRC2C,PLCB1,ARC,CRTC1,TPM1,TRIO,VGF,UPF3A,MPPE1" Drug 6821_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ALK,BIN1,EPB41L5,PPP4R4,SYNJ1,ARHGAP33,CLGN,RAB33A,PLAA,CLTB,COL9A3,NECTIN3,CPS1,MAML1,RUSC2,SV2B,DTNA,ACSL4,ZNF589,RUNDC3A,GRIK5,HLF,HNMT,ITGAM,MIA2,MID1,MMP16,ADAM22,MSR1,NEFM,TMOD2,TCP11L1,SEMA6D,ASAP3,SPTB,CAMTA2,ARHGEF9,KIAA0930,DOCK9,BEX4,UCHL1,HPS4,ITM2C,KAT6A" Drug 2164_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG2,FAM131A,SLC4A4,SLC16A4,CLGN,SOCS6,CREM,CRY2,RNF14,SIPA1L1,C2CD2L,DTNA,MBNL2,C3orf18,EIF1,PRELID3A,GALC,ALDH1L1,ADAM28,GNAO1,GRIK5,MAP4,MBNL1,ZNF862,NFYA,CNOT4,PLCL1,PURG,LRP12,POLR2F,MAPK10,PTPRN2,EMID1,AMBRA1,BTBD3,HECW1,LHPP,ST5,PLCB1,EXOC7,R3HDM1,CDK20,CLIP2,KLC2" Drug 2143_DN Gramine [87-52-5]; Down 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ABHD6,APBB2,CAMK2G,SOCS6,RAB33A,ARHGEF10,CSNK1E,TM9SF4,DGKG,DAPK3,HIPK3,PLXNC1,ELN,RASGRP2,KAT8,SEMA4D,FLT1,AFF2,INPP5K,SRCAP,USP19,MSL3,POLL,LILRA2,IDH3A,KCNJ5,MEF2C,PLCB2,POU6F1,PTPRN2,CEP97,DPF2,RXRA,ZNF821,SH3BP2,EPN2,FAM214B,DOK5,PLCB1,TPM1,PLPPR2,VIPR2,XRCC4,EVI5" Drug 3048_UP Propofol [2078-54-8]; Up 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ACHE,ANK2,APC,RGS20,ATP2B2,CFAP410,P2RX6,LHX2,CNTFR,SUSD5,PDE4DIP,SPOCK3,EDN3,CALCRL,RCAN2,BAIAP2,SEPT9,ZNF276,GRIK5,FAM107A,SCIN,IL6ST,ADAM11,MYCN,OPRL1,PCDHGC3,PTPN13,PTPRN2,RGS12,KCTD17,MAP6D1,CCDC92,PREX2,TMCC1,IZUMO4,PEG10,DBNDD2,LHPP,TBCEL,PHF24,BHLHB9,TRIO,VGF,SLC17A7" Drug 5054_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "C1QTNF3,APAF1,ATP2B2,MYOM1,ADAM23,ADGRB2,NRP2,ST3GAL5,CACNA1A,KYAT1,LDB2,LY86,VCAN,PDE4DIP,DBT,MFAP3L,SGSM2,CDON,EDN1,SPEG,FAM49B,OGA,GLI2,GNAO1,GSTM5,C2orf72,KIT,MATN3,KITLG,PDE4A,MAPK4,PID1,GAL3ST4,RNASEL,ZNF334,KDM4B,POGZ,PHLDB1,ADGRL3,TBCEL,RPRM,VSNL1,KCNK12,SLC17A7" Drug 3334_UP Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG2,ADRA1B,NME5,C1QTNF1,LTBP4,ADAM23,CAMK2B,ARHGEF2,TAOK2,LHX2,NCOR2,CSF1R,DAPK1,DMPK,CNNM1,EGR3,ERCC2,ZNF589,SCARA3,DCTN2,IQGAP2,TMEM8B,PCDH17,HPGDS,PRUNE2,ADAMTS13,ICA1,KIF5A,LAMA2,MMP17,PDE4B,LRP12,ASAP3,SLC11A1,BTBD7,SOX3,HECW1,ARHGAP26,ATP10B,ST5,TCF4,TRO,FAM155A,PLSCR4" Drug 1513_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA2A,ADRA1D,APOC1,CDK13,SLC4A4,SLC2A11,CACNA1I,ARHGEF1,ARHGAP33,CNN3,SLC4A8,TOM1,CELSR3,TNK2,ELN,REEP2,FHL1,ERAP1,DISC1,GLYR1,POLL,TDRKH,GRIK5,GSN,HLF,HSF2,ICA1,IL6ST,ZNF862,NELL2,NOVA1,CLDN11,CDK18,MAPK10,PRPH,RASA3,EPN2,ELMO2,BTBD7,SPART,STX1A,SYN2,PIK3R5,WIPF1" Drug 4572_UP Cyanocobalamin [68-19-9]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADRA1D,AGT,PTCH2,ATP2B2,SLC2A11,SYNJ2,CFAP410,STOML1,ABCG2,CNTFR,MYRIP,CREM,NCOR2,RGS6,CNTNAP2,RIMS2,DAPK3,BRINP1,MFAP3L,DTNA,ELN,MTSS1L,NSG1,ZNF44,ERAP1,SIGLEC8,GPD2,PRUNE2,TPPP,GRM8,KHK,TAGLN3,NPTX1,PFKFB2,LRRN3,KHDRBS2,FRMPD1,HECW1,ASTN2,TAL1,TK2,SEMA3B,FAM13C,GAN" Drug 4544_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASPHD1,AP2A2,APC,SHROOM2,STX16,RAB26,SIPA1L1,MFAP3L,PARD6A,DYNC1I1,DPH1,ANKMY1,FGFR1,IQCG,ANKFY1,DENND2A,GLYR1,MSL3,GPD2,GPER1,RNFT2,GUCY1B1,SHISAL1,SCAMP5,MMP16,NDP,PLCD1,SLC25A23,PPP5C,CSRNP3,TROVE2,SS18,IQCE,DOCK9,CRTC1,DNAH7,CABIN1,UGT8,PLPPR2,LMF1,NDRG4,MAP3K12,HPS4,KCNAB1" Drug 7146_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,SRPX,FAM131A,MADD,CFLAR,CAMK2G,CLCN3,DZIP3,PARD6A,SUGP2,EGFR,PCOLCE2,F8,SCML2,ST3GAL6,POLR1B,SEC23B,EFCAB2,GHR,COPS8,GPD2,DIDO1,HNMT,IFI16,FAM69A,NF1,SETD4,PDPK1,PIK3R1,PPP3CC,GTDC1,NCBP3,TMCC1,PDZD2,TSPYL2,ARHGEF9,HIRA,UBE3A,LMF1,TFIP11,UPF3A,KAT6A,ADAMTSL3,AAAS" Drug 4222_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASPHD1,BIN1,ARRB2,PDE8B,ST3GAL5,CACNA2D2,LY86,ARMC8,AATK,CSF1R,MFAP3L,PLPPR4,EXOG,DTNA,COQ7,ETV1,TRMO,DENND2A,KCNMB4,SHISAL1,FAM69A,LMO2,PACRG,MN1,NDP,CNOT4,SLC11A2,CLDN11,PPARA,PTCH1,CSRNP3,FBXO11,ANKRD6,PPP4R3A,SLC11A1,LIMCH1,KDM4B,THSD1,PLCB1,IQCE,TRIM2,THRA,KCNAB1,EPM2A" Drug 3485_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASIC1,ABHD6,C1QTNF3,APAF1,APLP1,BACH1,CFLAR,RCBTB2,CNOT8,SPOCK2,DUSP9,CNNM1,PLXNC1,ACSL4,SCML2,GFER,STON1,JAK2,KIT,TM6SF1,ADAM22,NF1,PPP3CA,GRAMD1C,SAMD9,FAM184A,TCP11L1,RPS6KA2,FBXO11,ANKRD6,FAM214B,BTBD7,SMARCD3,TMCC1,KDM4C,DIP2A,PHLDB1,VPS13A,TACC1,EXOC7,KIAA0930,PCDHA6,REEP1,TFIP11" Drug 6167_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADRA1D,AP2A2,MTUS1,ANK2,APAF1,APOC1,SEMA4G,MARK4,ZSCAN18,KIF1A,CDO1,HOMER3,CREM,SH2B1,CRY2,CTH,GSDME,DTNA,CELSR3,ELN,DLC1,FHL1,PRELID3A,GAA,PRUNE2,SOX21,ICA1,IL6ST,MAP4,N6AMT1,ZNF862,PDE4D,BCAS3,WDR25,RPS6KA2,ST6GAL1,PREX2,EPN2,SIRT2,IQSEC2,DDN,TBCEL,VIPR2,MAP3K12" Drug 2514_DN Ungerine nitrate; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,AMT,APBB2,NFS1,KRIT1,CD86,AP4M1,PLAA,ENTPD4,VCAN,RUBCN,DTNA,TUBD1,MTSS1L,ZNF589,GAA,SLC2A6,TJAP1,MAP4,ZNF862,MYT1,CNOT4,GPSM2,PLCB2,LRP12,MINDY2,ZCWPW1,GSTCD,ZNF671,MRAS,FBXO11,BTBD7,ZHX3,ZBTB43,SS18,CEP68,ARHGEF9,EXOC7,SZT2,SMUG1,LMF1,XRCC4,NT5M,ST7" Drug 6601_UP Retrorsine [480-54-6]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADD1,GAS7,APOC1,CFLAR,CACNA1G,DGKI,TAOK2,ENTPD4,ARHGEF10,VCAN,CNTNAP2,MFAP3L,SRPK3,PIPOX,FAM198B,AGAP2,SIGLEC8,GRIK5,FAM107A,IRAK3,ICA1,SHISAL1,PACRG,NF1,NOVA1,PRKAR1B,MAPK10,PTPRB,C1orf54,SUSD4,KHDRBS2,NEK11,MRAS,SLC8A1,SPTB,ZEB1,TIMP4,TPM1,AMACR,ZNF74,SLC17A7,KCNAB1,EPM2A,DPF3" Drug 6500_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AK2,ALK,BEGAIN,AMPH,SEMA7A,APOC1,CDK13,SCAPER,CA4,CALB2,CAMK2G,P2RX6,SLC4A8,HAPLN1,TBC1D5,RCAN1,DTNA,MBNL2,ING4,OLFM1,FHL1,ANKFY1,POLL,KCNN2,MATK,MGAT3,MMP16,DUSP26,PRPH,PTPRD,NUDT11,RTN1,SBF1,SCN2B,FNDC3A,ST5,TRIM2,ZNF34,TLR4,CHST5,AMACR,XRCC4,SLC30A3,JPH3" Drug 2674_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "MTUS1,ALK,BIN1,OGT,APBB2,SLC2A11,AZGP1,BMP7,MYRF,RAB26,SUSD5,DZIP3,PPP1R16B,ZNF337,DGKG,MAMLD1,E2F5,MBNL2,FHL1,PDLIM5,SIGLEC8,GCNT2,GNAL,STON1,MEF2C,AFDN,PCDH9,PMP22,MAPK10,CNNM2,CCDC102B,SLC9A5,CXXC4,SOX15,ZC3H13,SPTAN1,STXBP1,TRIM2,TIAM1,TPM1,TRO,PLPPR2,MAP3K12,EVI5" Drug 6626_DN Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,TRMT9B,APC,SEMA4G,MYRF,CFAP410,CBFA2T2,STOML1,AATK,CNTNAP2,DZIP3,DCAF4,TNK2,ZNF549,BAIAP2,TRAF3IP2,GAD1,LPAR4,SYNPO,IFI16,SCIN,MAPT,MBD1,AFDN,LYRM9,MAPK7,PTPRE,PTPRH,RIPOR1,ZCWPW1,EPN2,FAM214B,SMARCC2,DDN,TROVE2,JMJD6,ASTN2,KIAA1107,SMG6,RPGRIP1L,TPM2,TRIO,LMF1,NAV3" Drug 4012_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG2,ADD2,RASL11B,SLC4A4,ADAM23,NRP2,SCAPER,CACNA1G,PLEKHB1,NRXN3,CSF1,LRIG1,CNTNAP2,EXOG,EDN3,ETV1,FAM198B,PRELID3A,FYB1,GNG4,GRIK5,GRM2,RASSF8,KCNN1,MMP16,P2RY1,PALM,LRRN3,PRPH,GAL3ST4,RFX2,RGS12,RNASE1,NEK11,SCN2B,MRAS,SH3BP2,ST8SIA1,SLA,ATP10B,TROVE2,TACR1,TAL1,TUBB1" Drug 5808_UP Tomatidine [77-59-8]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADGRF5,SLC4A4,RGS9,CFLAR,ST3GAL5,CACNB4,SEPT7,CHN2,ABCG2,IQCK,CRMP1,GIT2,DBT,CDON,SEMA4D,PDLIM5,FYN,SYT17,SEPT9,LYVE1,GLI2,PRUNE2,GPER1,GPR37,INPP5B,LIFR,MT1M,TAGLN3,SERPINI1,RETREG1,WDR25,PID1,FAM184A,SUGCT,ASAP3,FNDC3A,TMCC1,ZC3H13,ARC,SYN2,SYT1,TRIM2,CLDND1,MAP3K12" Drug 834_DN 5211181; Down 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ALCAM,BIN1,SCAPER,LRRFIP1,QKI,ARHGEF6,CSNK1E,DCAF8,DTNA,FCF1,ING4,MRNIP,MTSS1L,SCML2,ST3GAL6,FHL1,ANKFY1,CINP,FAM49B,ERAP1,SEPT9,POLL,GPER1,MAP4K5,MUM1,DHX35,CNOT4,SMIM7,STRN3,APTX,CEP97,RAD51D,BTBD7,POGZ,DIP2A,FAM208A,TMPO,METTL3,VGF,XRCC4,ZBTB14,ZNF45,UBE3B,TIGD6" Drug 3168_UP Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "BIN1,ARHGDIG,RGS20,MTMR3,MYRF,CFAP410,HAP1,CAMK2B,ARHGEF2,TPP1,LY86,PYGO1,BRINP1,DTNA,DUSP9,EDN3,DLC1,FYB1,SEPT9,GATM,NEU3,PCDH17,GNAL,GRIK4,GRM8,GSN,SOX21,KCNQ3,MITF,LRRN3,DCHS2,PTX3,CPEB3,SLC4A3,SLC6A8,SP2,ZC3H13,PLCB1,SYT5,SLC19A3,AMACR,MKRN3,TFIP11,SLC17A7" Drug 5816_UP Ungerine nitrate; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "MTUS1,BEGAIN,AMH,AMPD3,ST3GAL5,LDLRAD4,CA12,KYAT1,SYNGR3,CNOT8,ABCG2,IQCK,CSF1R,CTH,TM9SF4,OPTN,EGFR,FGFR1,HPCAL4,SEMA4D,PDLIM5,ERAP1,SYT17,CACFD1,SYNPO,KHK,AFDN,MMP16,TAGLN3,NOVA2,PPP5C,FAM184A,ASAP3,ARHGEF40,SMARCA4,TMCC1,DDN,CEP68,ASTN2,IQCE,PCDHGB6,PCDHA5,RIMBP2,WIPF1" Drug 3207_DN Debrisoquin sulfate [581-88-4]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ALCAM,AMT,FAM131A,APOC1,BCAS1,PPFIA3,RGS20,MARK4,CAMK2G,SCARB1,SOCS6,B4GALT6,QKI,SOCS5,HDAC4,MFAP3L,CDON,TOM1,HSD17B14,COQ7,FHL1,SEPT9,SRCAP,POLL,ELOVL5,HNMT,IL6ST,MAP4,MBD1,ADAM22,PDE4A,MINDY2,MAPK7,CNNM2,RGS12,FBXW7,EMID1,SMARCD3,KDM4C,TROVE2,CABIN1,HIRA,VGF,VIPR2" Drug 4355_DN Homosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA1,ADRA1D,C1QTNF3,AMH,PDE8B,B4GALT6,WHRN,ABI3BP,MAML1,SLC12A6,MBNL2,EIF4G2,OLFM1,SCARA3,AGAP2,DISC1,RUNDC3A,GLYR1,HNMT,KHK,KIT,IPO5,MAP4,MID1,ZNF862,SERPINI1,RETREG1,PLXNB1,POLG,TCP11L1,SUPT20H,ASAP3,FNDC3A,PPP4R3A,KDM4C,CLSTN2,EXOC7,ZEB1,CRTC1,SLC44A1,FLRT2,PLPPR2,ZNF24,KAT6A" Drug 4245_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "PKP4,APC,GAS7,BCAS1,SLC2A11,ATP6V0A1,NRP2,MTMR3,CFAP410,HAP1,RUNX1T1,FOXN3,CNTN1,HAPLN1,LRIG1,CHRDL1,HIPK3,COQ7,DCTN2,GRIK5,ITPKA,KIT,MAP2,LYRM9,NF1,PCBP3,CLDN11,LRRN3,PTPRB,PTPRN2,PTPRO,ACSS3,ENOX1,SNCA,TMCC1,ZHX3,ARHGAP26,DMXL2,AP4E1,ZNF34,UCHL1,FLRT2,ZNF225,NLRP3" Drug 6428_DN C75; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "APC,ST3GAL5,CFAP410,CBFA2T2,RAB26,PICK1,PDE4DIP,CNTNAP2,PHF14,PPP6R2,DCAF8,DAPK3,LYPD1,SPOCK3,EZH1,KAT8,ZNF589,CINP,PDLIM5,SRCAP,POLL,GNG4,KIFC3,MAP4,MITF,CNOT4,SMIM7,MAPK7,PTN,PTPRH,RPS6KA2,SH3BGR,SLC4A3,SMARCC2,ZNF415,SPTAN1,THSD1,ASTN2,TIAM1,RUNDC3B,ZKSCAN5,WIPF1,WNT7A,PCBP4" Drug 5605_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASIC1,ADRA1D,AMPH,BIN1,KSR1,CA4,CHN2,CNTN1,AATK,CSF1,SPOCK2,DBN1,TOM1,RASGRP2,REEP2,DLC1,FHL1,FYN,PCDH17,POLL,GRIN2C,KCNB1,MAP2,MGAT3,NOVA2,PFKFB2,SERPINI1,MAPK7,KHDRBS2,TCP11L1,EMID1,KCNIP1,ZNF821,MRAS,SLC11A1,ZNF334,SPTB,SYP,WSCD1,OBSL1,VGF,SLC30A3,KCNAB1,FAM13C" Drug 5685_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASIC1,ADORA1,ADGRF5,LTBP4,SYT13,CDC42BPA,DNAH17,AZGP1,CACNA2D2,CRMP1,CSF1,ARHGEF4,RIMS2,HDAC9,SPOCK3,RASL10A,DISC1,AP4S1,SOX21,INPP5B,LAMA2,MN1,NECAB2,PRKCB,MAPK7,PBRM1,PNMA8A,TCP11L1,ZNF821,PREX2,SLC2A5,KANSL3,SLC9A5,PDZD2,ATP10B,SYN2,EXOC7,TCF4,PCDHGB6,SZT2,PCDHGA10,DOCK9,PIK3R5,EPM2A" Drug 4097_DN Gelsemine [509-15-9]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AMH,APC,PPP4R4,CDK13,ATP1A3,AZGP1,FOXN3,ARHGAP22,RAB28,AKAP7,AKAP5,NCOR2,SPOCK2,MFAP3L,EDNRB,EIF4G2,IRAK4,MTSS1L,ETV1,ST3GAL6,ZNF589,OGA,POLL,GRIK5,IL12A,P2RY13,NNAT,CCSER2,PLCD1,PLXNB1,POU6F1,ZSCAN2,KCTD17,MRAS,FRMPD1,DOP1A,UNC5B,SPTB,SYP,PCDHGA10,GPR161,TK2,OSBP2,ZNF24" Drug 3685_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ABHD6,APBB2,CDK13,ADAM15,SCAPER,CBFA2T2,LARGE1,FOXN3,SOCS6,CHN2,RAB28,IQCK,NCOR2,CSF1,VCAN,PDE4DIP,DZIP3,CTH,PLPPR4,PDLIM5,CACFD1,GUCY1B1,ELOVL5,HNMT,KCNJ5,MBNL1,NFYA,PLEC,PRPH,TMEM231,DZIP1,ELMO2,SNCA,SS18,NXT2,SYT1,COBL,ASTN2,KIAA1107,GPR161,BEX4,TPM2,TRIO,TRPM2" Drug 4366_DN Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "LTBP4,CDC14B,DNAH17,ARHGEF1,FOXN3,QKI,PICK1,CNTFR,CSF1,CNTNAP2,DAPK3,HIPK3,FGF13,FGFR1,BAIAP2,SCARA3,SEMA4D,ALDH1L1,USP19,RUNDC3A,GLYR1,RAB30,GPD2,TDRKH,KIT,LIG4,LRP12,ELOVL2,TRIM68,ZNF821,RASA3,ASAP3,BTBD7,TSNAXIP1,TROVE2,PHLDB1,JMJD6,VPS13A,PLCB1,KIAA1107,ZEB1,CRTC1,FLRT2,ITM2C" Drug 6732_DN N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AK2,BIN1,ARHGDIG,ATP1A3,KIF1A,SYNJ1,CACNA1I,LDLRAD4,B4GALT6,WHRN,CRMP1,NCOR2,CNTNAP2,BRINP1,EIF4G2,BAIAP2,LYVE1,ICA1,SCIN,KCNN1,MN1,MYT1,NF1,PLCD1,PLXNB1,PRPH,BCAS3,CNTLN,KIRREL1,SH3BP2,LIMS2,FAM214B,SMARCD3,RBM34,SPTAN1,DDN,PHLDB1,EXOC7,TCF4,THRA,TNS1,METTL3,NT5M,PCBP4" Drug 5242_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA1,ADAM23,ADGRB3,KSR1,AKAP7,AKAP6,COL9A3,OSBPL3,DCAF4,BRINP1,DMPK,TENM1,TNK2,HSD17B14,MTSS1L,FOXF2,AFF2,GFER,PCDH17,POLL,GPD2,GRIK5,VSIG4,KCNH2,LSS,KITLG,ADAM22,MYT1,NEFM,CLDN11,TMOD2,SAMD9,CCDC40,RASGRF1,KLHL11,S100B,SNAP25,SNCA,ZSWIM8,SYT5,DMXL2,PIK3R5,CHST5,PLSCR4" Drug 4679_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NME5,AMT,KCNAB2,ALDH7A1,SCAPER,LDLRAD4,SLC4A8,ARHGEF10,VCAN,DZIP3,DAPK3,ARMCX2,DPH1,EDNRA,CNNM1,MTSS1L,CDKL3,AFF2,GAD1,POLL,TDRKH,CNTRL,ICA1,TM6SF1,MEF2C,AFF1,NF1,PDE4D,STRN3,ZSCAN32,ZSCAN2,RGS4,ZFP30,FRMPD1,UNC5B,SPTAN1,ZBTB43,DDN,LHPP,AP4E1,THRA,TK2,NDRG4,KCNAB1" Drug 6788_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ABHD6,AP2A2,APBB2,ARRB1,PLA2G4C,NCOA1,SLC4A4,SCAPER,B4GALT6,SLC4A8,CRY2,ABCG1,ARHGEF10,APPL1,CTH,GIT2,DMTF1,EDNRA,HIPK3,ING4,ANKMY1,FER,OGA,BTN2A1,ATXN2L,MAPT,ADAM22,NNAT,CNOT4,SLC11A2,PCDH9,PLXNB1,MINDY2,PPP2R2B,TMEM104,NKAIN1,ZNF821,NUBPL,BTBD7,ARHGAP26,ELOVL4,PHLDB1,ARC,SMIM8" Drug 3064_DN Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "BRAP,BIN1,APAF1,DNAH17,KSR1,SYNJ2,HIP1R,FOXN3,CHRNA4,STOML1,CREM,TM9SF4,EXOG,HIPK3,PLXNC1,ING4,VPS26C,F5,OGA,ALDH1L1,SRCAP,CRCP,GNG4,LILRA2,DIDO1,LIG4,AFF1,NF1,NNAT,RETREG1,PLEC,RASA3,SH3BGR,SLC2A5,MAPKBP1,SNCA,SYT5,TRIM2,TLR4,TPM1,CDK20,TRPS1,CLIP2,PHTF2" Drug 7011_DN "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,PKP4,APBB2,CDC14B,NCOA1,CFLAR,CAMK2G,CCNT1,SYNGR3,FOXN3,CREM,NCOR1,CSNK1E,SIPA1L1,CTH,PPP6R2,MFAP3L,KIAA0753,PARD6A,SGSM2,DNM1,EXTL2,ERAP1,ZNF276,COPS8,MSL3,RNFT2,PADI2,DHX35,MAP4,TMEM260,TMEM231,ZCWPW1,SIRT2,ZKSCAN3,CDK5RAP2,ZSWIM8,SPTAN1,PBLD,PDLIM2,TBL1X,WBP2,RPRM,MAP3K12" Drug 6067_UP Ricinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AMH,BIN1,APC,PRX,ATP2B2,CFLAR,LY86,HAPLN1,CSF1,ARHGEF4,DCAF4,SEC14L5,EBI3,LRRC17,PIPOX,FGFR1,GAD1,CYP46A1,GSN,GSTM5,KCNB1,KHK,MPP2,MX1,MYT1,P2RY13,RETREG1,PLCD1,PPP2R2B,SAMD9,C1orf54,RGS12,SH3BP2,HKDC1,FAM214B,SNCA,PEG10,SPTB,ATP10B,EXOC7,TCF4,DMXL2,SZT2,SLC19A3" Drug 3616_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADD2,LTBP4,TRMT9B,BIN1,ATP2A2,ADAM23,ST3GAL5,CACNA1I,CDH2,SULT4A1,CNR1,WHRN,GREB1,HDAC9,ZNF804A,ELMO1,C3orf18,PTK2B,NSG1,FYB1,CSDC2,LILRA2,ZNF862,FXYD7,NF1,OGG1,OPRL1,PLCD1,PLCL1,CEP41,PTCH1,ZMAT4,RGS12,RASA3,CPEB3,PKNOX2,ARHGEF40,HECW1,CDK19,MCF2L2,SYN2,RIMBP2,TRIO,LAT2" Drug 6456_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AK2,SEMA6A,SRPX,APBA2,EPB41L5,BCAS1,CDC14B,SLC4A4,STX16,ADAM15,RAB29,ARHGAP33,HINFP,SIPA1L1,PDE4DIP,GIT2,DBT,FEM1B,CNNM1,COQ7,DENND4A,CDKL3,TDRKH,GPER1,GPR37,MAP4,MAPT,LYRM9,NCAM2,NF1,P2RY1,ZNF821,CXXC4,LIMCH1,SPART,TROVE2,THSD1,ASTN2,EXOC7,FBXW11,VAV1,VLDLR,KLC2,HPS4" Drug 6817_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA1,AGT,ASPA,ATP2B2,AZGP1,RGS9,LDLRAD4,ARHGEF1,RAB33A,STOML1,CNTN1,CPS1,OSBPL3,SPOCK3,DMPK,ERCC2,ST3GAL6,ZMYND10,FGF13,HPCAL4,FYN,GABRG2,SRCAP,MSL3,SPACA9,HLF,HNMT,ICA1,TAGLN3,NOVA2,C1orf54,TCP11L1,ZNF821,ASAP3,ST6GAL1,FAM214B,KDM4B,IZUMO4,TSPYL2,WSCD1,RUNDC3B,SLC17A7,TIGD6,JPH3" Drug 3937_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASIC1,AP2A2,BIN1,KCNAB2,PLA2G4C,MARK4,TAOK2,CLTB,CNTFR,AKAP7,SH2B1,CRMP1,ARHGEF4,DBN1,RUSC2,CDON,DUSP9,PIPOX,ANKMY1,FGFR3,FHL1,KHDRBS3,TMEM8B,SEPT9,GPER1,ITPKB,KCNN1,MAPT,AFF1,MSR1,NPY,SETD4,PDE1C,PPP5C,MAPK7,RIPOR1,SEMA6D,PEG10,ARHGAP26,LHPP,TNS2,TMEM121,WIPF1,KCNAB1" Drug 3889_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AMPD3,PRX,MARK4,CACNA1I,CFAP410,CNTN1,FAM149A,MYRIP,OSBPL3,RASSF2,DYNC1I1,SHANK1,C3orf18,FGFR3,PDLIM5,MSL3,POLL,TDRKH,PCLO,GRIK5,RNFT2,ICA1,KIT,SMAD1,MN1,NNAT,PALM,PAX6,PFKFB2,NECAB2,C19orf57,PTPRN2,MARCH1,C1orf54,ZMAT4,TRIM68,LIMS2,KDM4B,IZUMO4,SAMSN1,WSCD1,ICAM5,TRIO,LAT2" Drug 2761_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NME5,LTBP4,APOC1,BACH1,SYNJ2,MTMR3,CA4,HAP1,USP2,LHX2,STOML1,NCOR2,PDE4DIP,RIMS2,ZNF804A,DMPK,SLC12A6,OPTN,MBNL2,STX2,ETV1,ZNF589,PRUNE2,GPER1,ADAMTS13,IRF8,MAP4,MX1,PCBP3,FA2H,CEP41,SAMD9,ELOVL2,C1orf54,EMID1,RPS20,SATB1,ARHGAP26,IQSEC2,CRTC1,PCDHA5,CABIN1,FAM155A,EPM2A" Drug 3119_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "SYN3,ABHD6,AP2A2,SYT13,CDC42BPA,APBB2,BCAS1,PRX,GYG2,HAP1,RUNX1T1,COL9A3,CRY2,PDE4DIP,PARD6A,SPOCK3,CDON,CELSR3,PLEKHA1,EIF1,GPR162,KCNMB4,SCIN,ITPKA,MAP4,NTRK2,PFKFB4,PLCB2,NECAB2,POU6F1,CEP41,PRPH,PTPRN2,ENOX1,RASGRF1,MAP6D1,PKNOX2,PEG10,SYP,MTCL1,DNMBP,TBCEL,LMF1,KCNAB1" Drug 2568_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AMH,BIN1,APBB2,BMP7,FUBP1,CACNA1G,MAGI1,CHRNA4,EPS15L1,CNN3,CRYBB1,VCAN,PDE4DIP,RIPOR2,C3orf18,COQ7,ZNF549,IQCG,PDLIM5,SIGLEC8,ADAM28,LYVE1,GPD1,PRUNE2,GRM8,SOX21,GUCY1B1,HNMT,TJAP1,KCNF1,KCNQ3,LAMA2,PACRG,MAP4,NNAT,STRN3,POU6F1,PPP2R2B,PTPRG,PID1,FAM214B,PEG10,MCF2L,KCNK12" Drug 6768_DN Tamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ABHD6,SEMA6A,BIN1,APC,ARHGEF7,GYG2,CA12,MAGI1,SOCS6,SLIT2,EPS15L1,PLAA,QKI,PICK1,AKAP12,CSNK1E,GREB1,DCAF8,ZNF337,C2CD2L,EDNRA,PCOLCE2,FAM198B,FHL1,MSL3,KCNMB4,RASSF8,ELOVL5,KCNF1,LSS,GIT1,ADAM22,LRP12,ELOVL2,FAM184A,RET,SBF1,LIMCH1,ARHGAP26,ARC,AP4E1,HIRA,TFIP11,UBE3B" Drug 4842_DN Picrotoxinin [17617-45-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASIC1,APBA2,APLP1,PPFIA3,ARRB1,CFLAR,CCNT1,ARHGAP33,MAGI1,CRLF1,CACNA2D2,ARMC8,CNTNAP2,DTNA,EDNRA,FCF1,ERCC2,ZNF589,FGFR1,HNMT,INPP5B,IPO5,MAP4,MPP2,CNOT4,OGG1,RETREG1,SLC25A23,TMEM104,RGS12,SH3BP2,FAM214B,SLC6A8,INTS9,SNCA,TMCC1,CEP68,EXOC7,IQCE,SATB2,TRIO,PLPPR2,KCNAB1,UBE3B" Drug 6911_UP NS-398; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,SYT13,CDC42BPA,APC,SEMA4G,PRX,MARK4,KIF1A,MYRF,CBFA2T2,SOCS6,COL4A5,CSF1,CSF1R,PPP6R2,GIT2,SEMA4D,GLYR1,GPER1,CACFD1,HNMT,TJAP1,IL6ST,MATK,TM6SF1,SLC11A2,PLCD1,PPP5C,VPS13C,WDR25,CCDC40,RGS3,KCTD17,EMID1,PREX2,PPP4R3A,KIF13A,FAIM2,RBM34,PBLD,CLDND1,KCNK12,ADAMTS9,GAN" Drug 3939_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG2,C1QTNF3,CDC14B,SEMA4G,CFLAR,ARHGAP33,PDE4DIP,DBN1,HIPK3,HSD17B14,DLC1,ZNF589,FGFR3,GCNT2,SRCAP,USP19,PCDH17,MSL3,GPD2,ADAMTS13,KPNA5,MAP4,MSI1,MSR1,NF1,PDE1C,PFKFB2,MINDY2,CEP41,PRKCB,ZDHHC14,TCP11L1,RPS6KA2,EMID1,SEMA6D,SBF1,NLGN1,EPN2,LIMCH1,KDM4B,ATP10B,RGL1,SYN2,PHTF2" Drug 1017_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "MARK4,SCAPER,GYG2,SRSF11,B4GALT6,CLCN3,ABCG1,PPP6R2,DBT,PARD6A,DTNA,KAT8,NOP56,EFCAB2,CGREF1,CSPG5,INPP5K,TXNL4A,HTATSF1,GPR37,FICD,DHX35,MAP4,MMP16,GIT1,SLC11A2,PCDH9,PLXNB1,LRP12,POLG,PPP5C,PRKAR1B,PEX26,SPTAN1,NXT2,SEPT8,ARHGEF9,SYT1,EXOC7,KIAA0930,HIRA,UBTF,SMIM8,PHTF2" Drug 4745_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADRA1D,AMT,APC,MARK4,SLC2A11,SYNJ2,CFAP410,CAMK2G,ARHGEF1,B4GALT6,TAOK2,EPS15L1,WHRN,NCOR1,MFAP3L,EDNRA,EIF4G2,HSD17B14,FGFR1,AFF2,TDRKH,STON1,GRM8,ELOVL5,HNMT,JAK2,MAP4,MID1,MSI1,ADAM22,SERPINI1,PRODH,GTDC1,RGS3,NEK11,SBF1,ASAP3,SPTAN1,CLASP2,CRTC1,PCDHA6,ZNF34,TRIO,LMF1" Drug 5619_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "SYN3,ASIC1,APAF1,KCNAB2,ARHGDIG,SLC4A4,ATP2B2,ADAM23,CA4,LHX2,PICK1,HAPLN1,NCOR2,CSF1R,SNPH,EDNRB,EGR3,ERCC2,PIPOX,FGF13,SIGLEC8,ATXN2L,KCNH2,KIT,NOVA2,PFKFB2,MAPK10,C1orf54,RASGRF1,CRTAC1,KCNIP1,KANSL3,SLC9A5,CXXC4,KIF13A,KDM4B,SYN2,SYT5,TACR1,WSCD1,SLC19A3,TRPM2,FLRT2,SLC17A7" Drug 3088_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "SYN3,AMPH,PKP4,CDC14B,MPDZ,BMP7,CCK,CHRNA4,TAOK2,LHX2,CNN3,AKAP7,CREM,DZIP3,SNPH,SPOCK2,DMPK,EDNRA,ING4,TNK2,EPB41,LRRC17,RASGRP2,BAIAP2,ALDH1L1,FAM107A,MAPT,AFDN,TAGLN3,P2RY1,GPR85,NECAB2,PPARA,PPP2R2B,CEP41,PTPRN2,KDM4B,IZUMO4,MTCL1,TBCEL,IQCE,TNS1,TUBB1,NLRP3" Drug 4602_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA2A,C1QTNF3,AMPH,PPP4R4,AZGP1,BAIAP3,CACNA2D1,CRLF1,RAB26,NRG2,CSF1,ARHGEF10,SNX29,ELN,APC2,GABRA3,SIGLEC8,NEU3,GPR75,POLL,GRIK5,VSIG4,SMAD1,MYCN,PIK3R1,RETREG1,NLE1,SNRK,PTH1R,ELOVL2,RTN1,MRAS,SNCA,ARHGAP26,CDK19,ATP10B,ELOVL4,ARC,PCDHA5,TEK,SLC44A1,RUNDC3B,KCNK12,SLC30A4" Drug 3544_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,APC,ADAM15,CFLAR,SCARB1,VAX2,ARHGAP32,INTS1,MED12,DTNA,PHC2,MRNIP,ANKFY1,COPS8,FERMT2,RNFT2,HNMT,ICA1,IL6ST,ITPKB,IPO5,MITF,MPP2,LRP12,MINDY2,PPP5C,TMEM104,SLC25A36,GSTCD,EPN2,ELMO2,UHRF1BP1L,SS18,CEP68,DNMBP,SATB2,TRIM2,TMPO,RUNDC3B,HIRA,ZBTB14,MAP3K12,MPPE1,AAAS" Drug 4100_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ANK2,APC,ZSCAN18,SLC4A4,BCHE,CAMK2B,CAPN3,RAB33A,STOML1,AKAP5,HAPLN1,ARHGEF4,PYGO1,C2CD2L,SPOCK3,DTNA,EDIL3,ETV1,KAT8,HPCAL4,AGAP2,NEU3,GNG4,GPD2,GSTM5,ATXN2L,LIG4,KITLG,ADAM22,LYRM9,NTRK2,SERPINI1,PLCD1,NECAB2,PTPRB,SCN2B,HECW1,TROVE2,SS18,COBL,SLC19A3,CRTC1,KCNAB1,RNF146" Drug 7543_DN DNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NME5,SPARCL1,APOC1,PPFIA3,ARHGDIG,ARHGEF6,AKAP7,WHRN,SLC4A8,FBXL5,TMCC2,PHF20L1,MBNL2,PCOLCE2,BAIAP2,SCARA3,FYN,IRAK3,ATXN2L,ELOVL5,MITF,MX1,NF1,PLCD1,MTRF1L,SNRK,RNASEL,SH3BP2,KIF16B,CCDC88A,LIMCH1,RBM34,ERC1,SPTAN1,CLSTN2,PHLDB1,PLCB1,THRA,VGF,VIPR2,XRCC4,PCBP4,KAT6A,TIGD6" Drug 5589_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "C1QTNF1,BIN1,APAF1,APC,CFLAR,CLGN,B4GALT6,CLCN3,WHRN,GREB1,DAPK1,FBXL5,ING4,MTSS1L,IGSF6,PTK2B,SCML2,ZNF589,TRAF3IP2,GLYR1,KCNN2,KHK,ADAM22,NEK1,NOVA2,LRP12,MINDY2,MAPK10,PTH1R,C1orf54,KCTD17,SH3GL3,CPEB3,SLC9A5,SPART,ATP10B,DMXL2,RPGRIP1L,DNAH7,TMPO,FLRT2,LAT2,SLC17A7,JPH3" Drug 3877_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "GAS7,DNAH17,SLC4A4,CACNA1I,CFAP410,CAMK2B,CBARP,LY86,CNTFR,AKAP7,IQCK,CRMP1,CNTNAP2,DYNC1I1,EDNRA,PCDH17,GLYR1,PRUNE2,GRIK5,GRM2,KCNJ5,KITLG,MMP16,ADAM22,NCF2,NELL2,NOVA2,PCBP3,OPRL1,C19orf57,MINDY2,CARF,SH3GL3,SLC2A5,SNAP25,IZUMO4,HECW1,SPART,TBCEL,SLC35G2,THRA,TRO,TRPM2,KCNAB1" Drug 2934_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG3,NDRG2,MARCH3,N4BP2L1,BACH1,CAST,SPAG9,KRIT1,SLC16A4,CD86,SOCS6,RCAN1,ING4,RRAGB,ZNF589,FER,TRMO,CINP,TXNL4A,LPAR4,IRF8,JAK2,KPNA5,GPR85,RETREG1,STRN3,PRKAB2,ZSCAN32,ZDHHC14,PPM1E,ZKSCAN3,ZNF667,TMCC1,KDM4B,KDM4C,ZBTB43,CEP68,JMJD6,AP4E1,TPM1,MAP3K12,PRDM10,KCNAB1,PHTF2" Drug 1333_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "OSBPL1A,PPFIA4,APAF1,GAS7,LDLRAD4,FOXN3,DZIP3,ARHGAP32,TBC1D5,ERCC2,TRMO,CINP,CELF1,CGREF1,BTN2A1,MAP4K5,ICA1,TJAP1,IL6R,INPP1,NF1,CNOT4,RETREG1,MINDY2,MAPK3,PTK2,RXRA,FAM102A,FNDC3A,ARHGEF40,SLC22A4,TSPYL2,TROVE2,POGZ,ARHGEF9,EXOC7,TNS1,TRPS1,VIPR2,NPDC1,EMSY,FIP1L1,MPPE1,PHTF2" Drug 6445_UP Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ASPHD1,LGR5,PDE8B,C5,LDLRAD4,CFAP410,CACNA2D1,CAMK2G,SPAG9,ENTPD2,CLGN,QKI,ARHGEF6,HAPLN1,CSF1R,DCAF4,HS3ST2,EDN1,AASS,CORO2B,AGAP2,DCTN2,SIGLEC8,HLF,ITGA7,MBD1,AFDN,ADAM22,PLCD1,MTRF1L,LRP12,SUGCT,TCP11L1,CPEB3,PPP4R3A,SNCA,ATP10B,SSTR2,SS18,WSCD1,PARD3,ZFP37,ZNF24,ZNF45" Drug 3319_DN Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "BCAS1,PPFIA3,CDK10,STX16,CFLAR,SYNJ2,MTMR2,GYG2,HAP1,CLGN,QKI,SLC4A8,ENTPD4,DAPK3,DCTN1,PARD6A,RCAN1,OPTN,SUGP2,PRELID3A,TDRKH,DHX35,IL6ST,ITPKB,NLE1,SLC25A23,PRKAR1B,TMEM104,RGS12,SLC25A36,SBF1,TRA2B,SH3BP2,FAM214B,BTBD7,THSD1,DIP2A,TACC1,ZKSCAN5,PLPPR2,EMSY,EPM2A,UBE3B,RNF170" Drug 6666_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "RALGAPA1,ASPHD1,AGT,SEMA6A,BMPR1B,KALRN,CPS1,PDE4DIP,DMPK,ING4,MRNIP,LRRC17,DLC1,FGF1,OLFM1,OGA,GNAO1,IRF8,KCNN1,KHK,MIA2,AFDN,MMP16,MSR1,MYH3,RASGRF1,RASA3,ANKRD6,SLC11A1,SLC12A4,ZNF334,CXXC4,ZNF423,ATP10B,PHLDB1,COBL,SYT5,FAM189A1,ZFPM2,TK2,FLRT2,LAT2,ZNF225,KCNAB1" Drug 2746_UP Tomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA2A,ADRB2,NME5,AK2,BIN1,CDC14B,MARK4,N4BP2L1,KSR1,BAIAP3,CA4,LHX2,AKAP7,TMCC2,PLXNC1,TENM1,NRN1,FGF13,SIGLEC8,POLL,GUCY1A1,ATXN2L,IRF8,KCNH2,MAP4,GIT1,MYO7A,NELL2,NF1,FAM184A,RNASE1,SLA,SLC8A1,KDM4B,HECW1,IQSEC2,TACR1,PCDHGA10,CRTC1,DICER1,CHST8,TPM2,EMSY,KCNAB1" Drug 1109_UP 3-hydroxy-(D/L)-kynurenine; Up 200; 9.2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "MADD,RIPK1,MPDZ,CFLAR,SYNJ1,SYNJ2,MTMR3,RAB29,CLCN3,ARHGEF10,KIAA0586,DTNA,PCOLCE2,RABEPK,STX2,CAMKK2,MPP6,GSN,PADI2,AGFG1,TJAP1,MARK3,NEK1,PLEC,PPP3CA,PRKACB,PTK2,ZSCAN32,CLIP1,WDR47,ELMO2,SMARCC2,KDM4B,SPATA7,UHRF1BP1L,TROVE2,CEP68,DNMBP,FAM208A,BEX4,SSBP2,UBTF,XRCC4,ZBTB38" Drug 608_DN NU1025; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AMPD3,CDC42BPA,AQP6,CDK10,ARNTL,ARSE,NCOA1,ADGRB1,CFLAR,RAB29,CCK,CD86,AP4M1,ARHGEF10,PDE4DIP,DRP2,E2F5,TUBD1,COQ7,RCAN2,GNG4,BTN2A1,SMAD1,TM6SF1,MPP2,ADAM22,MYT1,NELL2,NFYA,TREM2,SNX10,ELOVL2,SUSD4,RNASEL,DCUN1D2,TCP11L1,SH3BP2,KBTBD4,SMARCA4,FAIM2,DOP1A,ATP10B,TBL1X,PHF24" Drug 5099_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "MTUS1,APC,GAS7,ARHGDIG,ARSE,DNAH17,N4BP2L1,FOXN3,HOMER3,ENTPD4,CSF1,MYEF2,DTNB,EDNRA,HIPK3,LRRC17,PIPOX,CORO2B,ERAP1,SIGLEC8,ZNF276,STON1,ADAMTS13,SOX21,BACH2,ICA1,MAN2A2,LYRM9,NF1,MINDY2,PPP5C,MAPK7,C1orf54,RGS12,RPS6KA2,SH3BP2,KANSL3,ZNF334,SPTAN1,SAMSN1,PHLDB1,AMACR,SSBP2,LAT2" Drug 5994_DN Lymecycline [992-21-2]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "TRMT9B,CDC42BPA,APBA2,NCOA1,BCL7A,CFLAR,KYAT1,RAB28,PLAA,ABI3BP,ENTPD4,SH2B1,CNTNAP2,IRAK4,MRNIP,STX2,FGFR1,BAIAP2,SEMA4D,GAD1,DISC1,INPP5K,MSL3,GPR37,HNMT,ICA1,INPP5B,ITPKB,MAN2A2,MAP4,MMP16,MPP2,ZNF862,SAMD9,PTN,ZCWPW1,RGS3,RNASEL,SH3BP2,EPN2,CXXC4,PLCB1,NDRG4,EMSY" Drug 3836_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "SEMA6A,SEMA4G,SLC2A11,N4BP2L1,ADGRB1,MTMR3,CAMK2B,CBFA2T2,SCARB1,CHRNA4,LHX2,SULT4A1,CNN3,AKAP5,CRY2,NCOR2,CNTNAP2,PHF14,DAPK3,SPOCK2,ERCC2,AGAP2,AFF2,GLYR1,PRUNE2,ATXN2L,IL12A,AFDN,MMP16,SAMD14,NOVA2,PCBP3,ZSCAN32,RASGRF1,RASA3,ASAP3,PPP4R3A,KIF13A,PEG10,ZNF423,ZBTB43,ARC,PDLIM2,ZEB1" Drug 2879_UP Ethamivan [304-84-7]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "AP2A2,SRPX,LTBP4,AMH,AMPD3,APAF1,APOC1,PLA2G4C,CDK13,ADAM23,CFLAR,CACNA2D1,CBFA2T2,SIPA1L1,SPOCK2,BRINP1,RUSC2,CDON,EDNRA,C3orf18,HSD17B14,TPK1,GPER1,ICA1,ITGAM,KCNJ5,KIT,MIA2,TAGLN3,CNOT4,PFKFB2,PLTP,MINDY2,TRIM68,EMID1,MAPKBP1,ARC,DMXL2,KIAA0930,PARD3,TNS1,KCNK12,GDPD5,KCNAB1" Drug 3562_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NME5,PPFIA4,ATP1A3,ATP2B2,MTMR3,CACNA1I,MYRF,SLIT2,TPP1,HOMER3,WHRN,SUSD5,PDE4DIP,DOCK4,MFAP3L,SPOCK3,SEMA3D,RASGRP2,ZNF589,FGF1,CAMKK2,SEPT9,GRIK4,GRM8,KHK,ZNF862,SLC25A23,C19orf57,PRODH,PRPH,ZSCAN32,PTPRB,PKNOX2,CDK19,SYN2,TBCEL,TCF4,SZT2,SLC35G2,HIF3A,TIMP4,ICAM5,NT5M,SLC17A7" Drug 3362_UP Iodixanol [92339-11-2]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "ADORA1,SEMA7A,SLC4A4,CFLAR,SLC16A4,CBFA2T2,STOML1,PICK1,AKAP6,WHRN,ENTPD4,GREB1,RIMS2,HS3ST2,CDON,HIPK3,ERCC2,VPS26C,FAM198B,DLL3,FYB1,GABRG2,SEPT9,GSTM5,DHX35,ICA1,INPP5B,MSR1,TAGLN3,MYCN,FXYD7,NF1,SAMD9,GDPD2,SNRK,RPS6KA2,KCNIP1,COA1,ARHGAP26,FAM189A1,THRA,TRIO,ADAMTS9,PLSCR4" Drug 4433_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "SEMA7A,ATP2B2,KIF1A,GYG2,CBS,LDB2,CACNA2D2,NRXN3,WHRN,CRY2,RIMS2,SPOCK2,DTNA,ETV1,ANKMY1,REEP2,FGF1,OLFM1,GLI2,MSL3,SPACA9,ATXN2L,KCNH2,AFF1,ADAM22,PALM,PGAM2,DUSP26,MBOAT7,MAPK7,PTPRN2,GAL3ST4,RGS4,RNASEL,CPEB3,LIMS2,PKNOX2,ARHGEF40,SNAP25,ZSWIM8,RBM26,TPM1,TRIO,SPHK2" Drug 7350_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "CFLAR,CACNA1I,TPP1,FAM189A2,QKI,CSF1R,LRIG1,CNTNAP2,FAM169A,TBC1D5,GIT2,SPOCK3,ING4,ERCC2,ANKMY1,ZNF589,FGF12,RUNDC3A,STON1,GRIK5,ELOVL5,HNMT,INPP5B,KIF5A,LSS,MEIS2,MSI1,ADAM22,NF1,SLC11A2,PRPH,SNRK,FBXW7,SBF1,ZNF821,SNCA,TROVE2,TTBK2,PCDHGB6,CRTC1,FAM155A,LMF1,XRCC4,SEMA3B" Drug 4751_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "NDRG3,BIN1,AMT,CA4,CLGN,FOXN3,NCOR1,MAML1,MFAP3L,C2CD2L,DTNA,EDNRA,EIF4G2,ACSL4,ZNF589,BAIAP2,AFF2,PDLIM5,FAM49B,GPD2,MAP4K5,INPP1,KITLG,MITF,KCTD15,MINDY2,PRKAR1B,ELOVL2,SBF1,COA1,RBM34,TROVE2,CAMTA2,VPS13A,PLCB1,EXOC7,IQCE,PCDHA5,BEX4,TNS1,PLPPR2,VGF,SPHK2,EVI5" Drug 6328_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.80E-06 3.42E-01 2.24E-04 2.53E-03 44 197 "BRAP,OGT,CFLAR,SPAG9,TAOK2,QKI,ARHGEF4,TM9SF4,GIT2,LYPD1,DYNC1I1,AASS,FGF13,CAMKK2,TXNL4A,GNG4,GPD2,FAM69A,JAK2,MAN2A2,ZNF862,OCRL,CLDN11,PLCD1,MAPK9,ZSCAN32,PTPRN2,BEND5,RGS3,RPS6KA2,CSRNP3,CDK19,FBXW11,KIAA0930,TRIM2,ZNF34,TK2,PARD3,CABIN1,NAV3,MPPE1,ST7,ACTR3B,RNF146" Drug 3890_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.96E-06 3.49E-01 2.28E-04 2.57E-03 43 191 "AP2A2,DOC2A,KCNAB2,GAS7,SYNJ2,CBFA2T2,VAX2,NECTIN3,SH2B1,PDE4DIP,RIMS2,PPP6R2,MAML1,DAPK3,DBN1,HIPK3,EGFR,PLXNC1,ING4,COQ7,NCALD,FHL1,TPK1,GCNT2,SRCAP,TXNL4A,POLL,DIDO1,MAP2,TM6SF1,NEK1,NF1,PLCD1,PLEC,LRP12,CEP97,SLC22A4,ERC1,ARHGAP26,IQSEC2,PLCB1,SMG6,SLC44A1" Drug 2955_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.96E-06 3.49E-01 2.28E-04 2.57E-03 43 191 "ABHD6,ACTN1,TRMT9B,AMPH,BIN1,CDC42BPA,BCAS1,RASL11B,CACNA1G,CAPN3,HOMER3,PICK1,ABCG1,DZIP3,ECM2,CNNM1,CELSR3,C3orf18,AGAP2,EFCAB2,ALDH1L1,PCDH17,PADI2,HNMT,KHK,TAGLN3,MYT1,NNAT,PCBP3,PFKFB2,PLCL1,PILRA,PPARA,PPP2R2B,ZFHX4,KCNIP1,EPN2,SLC11A1,SPTB,PDLIM2,UBTF,FLRT2,VIPR2" Drug 6680_DN Strophantine octahydrate [11018-89-6]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.96E-06 3.49E-01 2.28E-04 2.57E-03 43 191 "TRMT9B,APC,GAS7,SHROOM2,MARK4,LRRFIP1,LHX2,SMARCAL1,DCAF4,KLHL3,RHOBTB1,ETV1,SEMA4D,FAM49B,SYT17,STON1,CNTRL,MUM1,ITPKB,MEF2C,MIA2,MN1,PDCD2,GRAMD1C,WDR25,PTPRE,PTPRN2,BEND5,SUPT20H,ZFP30,DZIP1,CEP68,ARHGEF9,PLCB1,KIAA1107,TIAM1,HEY1,TNS1,SMUG1,WIPF1,XRCC4,ZBTB14,PHTF2" Drug 2861_DN Piracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.96E-06 3.49E-01 2.28E-04 2.57E-03 43 191 "SEMA6A,APOC1,RASL11B,STX16,CFLAR,SYNJ2,CA4,KRIT1,SRSF11,SOCS6,PLEKHB1,RAB28,FAM169A,DBT,DNM1,TSPAN5,HIPK3,CDKL3,FGFR1,DISC1,GLYR1,HTATSF1,KCNMB4,TDRKH,GSN,MAP4,TM6SF1,PDPK1,PIK3R1,PRKAB2,ELOVL2,RGS3,SLC25A36,SEC14L1,TRA2B,FNDC3A,ZBTB43,THSD1,STX1A,TBL1X,VGF,EMSY,EPM2A" Drug 6390_DN 5707885; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.96E-06 3.49E-01 2.28E-04 2.57E-03 43 191 "LTBP4,CDC42BPA,BCAS1,ARRB1,SCAPER,RUNX1T1,IQCK,CRMP1,ABCG1,SEC14L5,MFAP3L,FGFR1,TMEM8B,ALDH1L1,SRCAP,HAS2,SCIN,IL6ST,INPP5B,KIFC3,MEF2C,LYRM9,CDK18,PDE1C,PGAM2,PLXNB1,CEP41,ELOVL2,PTPRD,FBXO11,DZIP1,SLA,BTBD7,ZNF667,CEP68,TCF4,OBSL1,TMEM121,TNS1,SPHK2,MAP3K12,SEMA3B,KCNAB1" Drug 4755_DN 0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.10E-06 3.55E-01 2.32E-04 2.62E-03 42 185 "MARCH3,MPDZ,BLM,BMP7,SYNJ2,KRIT1,CBFA2T2,FOXN3,STOML1,SMARCAL1,C2CD2,CREM,ABCG1,GIT2,DPH1,MAMLD1,KMT5B,EGR3,TUBD1,VPS13B,CHST15,NBEA,JAK2,MBP,RBBP6,RET,KIF16B,KDM4B,ERC1,CLASP2,CEP68,ZC3H4,ARHGEF9,TACC1,MTCL1,FAM208A,TRIM2,SMUG1,LMF1,ZIC1,ZNF189,FZD3" Drug 5935_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.10E-06 3.55E-01 2.32E-04 2.62E-03 42 185 "ADRB2,BAIAP3,CLGN,CLCN3,PDE4DIP,SEC14L5,KIAA0319,TMCC2,FRY,FAM13A,BAIAP2,FYN,CYP46A1,TDRKH,PCLO,RNFT2,ITGA7,PCDH9,ENPP2,SERPINI1,RETREG1,PRPH,RADX,RPS6KA2,SMPD3,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,OGDHL,SOX15,ZHX3,PEG10,ARHGAP26,SPTB,RGL1,ZEB1,HEY1,RUNDC3B,CLIP2,SLC17A7" Drug CID000021218 Aliquat 336 Stitch 8.72E-06 3.82E-01 2.43E-04 2.73E-03 14 34 "CACNA1A,CACNA1B,CNOT8,EPS15L1,DNM1L,FOXO3,GPR37,PACRG,NF1,OPA1,MAPK9,MAPK10,RET,FBXW7" Drug 5243_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "SYN3,APBB2,EPB41L5,GAS7,FAM131A,CDK13,SLC4A4,SLC16A4,CDO1,VAX2,FHL5,CRY2,ARHGAP24,PARD6A,TMCC2,DMPK,PLXNC1,FLNC,FYN,GCNT2,RUNDC3A,GPR37,BTN2A1,HLF,IRF8,KIF5A,LSS,MID1,PLCD1,PPARA,CCDC40,ENOX1,SBF1,NLGN1,KANSL3,ARHGEF40,IZUMO4,ARHGAP26,RBM26,SYN2,PIK3R5,XRCC4,SPHK2,ITM2C" Drug 343_UP HA-1077 dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "CDC42BPA,APBB2,GAS7,KALRN,AP4M1,SOCS6,CNR1,ENTPD4,HINFP,EXOG,HIPK3,FEM1B,MBNL2,EGR3,SPEG,FGFR1,BAIAP2,SEC23B,FLNC,GLYR1,GRIK5,IL6ST,IPO5,NACA,NF1,NOVA1,NTRK2,SETD4,OGG1,PPM1B,MAPK10,MTMR10,SH3BP2,SLA,KBTBD4,ELMO2,SEPT8,TRIM2,PHF24,TMPO,METTL3,ZKSCAN5,WIPF1,LAMP5" Drug 5865_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADCY6,AGT,NME5,LTBP4,TRMT9B,MYRF,IL33,STOML1,CSF1R,SPOCK2,BRINP1,RCAN1,DTNA,EDIL3,AASS,TENM1,RRAGB,DCTN2,GALC,SEPT9,GLI2,MSL3,LPAR4,ICA1,KCNQ3,LAMA2,MT1M,NNAT,NOVA1,PRKAR1B,RGS12,KCNIP1,SAFB,DZIP1,SLC4A3,SLC11A1,RBM34,DOK5,ERC1,SMG6,TCF4,TMEM121,REEP1,FZD3" Drug 4422_UP Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,ADRA1D,KIAA1324,SEMA6A,AMPH,CDC14B,RASL11B,BAIAP3,CAMK2B,CCNT1,SULT4A1,LY86,WHRN,SNCAIP,VCAN,FAM169A,GREB1,BRINP1,EDNRA,EGR3,GPER1,JAK2,MEF2C,NF1,NPY,PFKFB4,FAT4,ENOX1,RET,RGS4,RGS12,FBXW7,RPS6KA2,SH3GL3,TROVE2,THSD1,WSCD1,PCDHGA10,SIK3,HEY1,TNS1,OSBP2,LAT2,ADAMTSL3" Drug 5487_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ABR,ABHD6,APBB2,NCOA1,KIF1A,BCL7A,ST3GAL5,SYNGR3,ZMYM4,RAB28,BAG4,FAM169A,DCAF8,ZNF337,GIT2,PARD6A,EDNRA,CNNM1,SUGP2,STX2,POLL,GNG4,PRRC2B,GPR37,IL6R,NFYA,PDE4B,SUPT20H,FAM214B,SPATA7,CEP68,PHLDB1,STX1A,TBL1X,ZNF34,CDK20,SMUG1,PLPPR2,VLDLR,ZNF74,HPS4,URM1,ST7,KAT6A" Drug 2069_DN Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF1,AMPD3,AMT,KCNAB2,APOC1,ST3GAL5,SMARCAL1,PPP6R2,PARD6A,SGSM2,SUGP2,ZNF589,FGFR1,CINP,FAM49B,DLL3,GAD1,SRCAP,ZNF276,COPS8,PRRC2B,GPER1,SYNPO,ICA1,ZNF862,SETD4,OGG1,SUGCT,DCUN1D2,RPS6KA2,ATXN2,SH3BP2,LIMS2,SIRT2,BTBD7,CDK5RAP2,SPTAN1,TIMP4,TK2,LMF1,TFIP11,UPF3A,NT5M,AAAS" Drug 6458_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,BEGAIN,CDC42BPA,GAS7,PDE8B,SCAPER,CBFA2T2,CLGN,CHRNA4,HOMER3,AKAP7,WHRN,CYBB,ARHGAP24,SPOCK2,MFAP3L,HS3ST2,AGAP2,FYB1,ZNF44,GALC,USP19,ITPKB,SMAD1,MSI1,ADAM22,NEFM,LRP12,MAGEL2,GDPD2,PTCH1,PTPRB,KCTD17,KLHL11,TCP11L1,PPP4R3A,COA1,PLCB1,PCDHA5,DICER1,XRCC4,SLC30A3,EMSY,KCNAB1" Drug 3617_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,LTBP4,EPB41L5,APLP1,PPFIA3,MTMR2,PLEKHB1,HOMER3,CNTFR,GIT2,DMPK,TOM1,EGFR,ING4,DENND4A,NCALD,ZNF589,GSN,ELOVL5,KCNN2,KPNA5,KITLG,CNOT4,RETREG1,PLCD1,ZSCAN32,ZSCAN2,NKAIN1,FAM184A,RGS3,ZNF821,FAM214B,BTBD7,COA1,ZHX3,LHPP,CLSTN2,EXOC7,TBCEL,TNS2,TPM1,ZKSCAN5,VIPR2,SMIM8" Drug 5993_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "SEMA6A,ANK2,ARHGDIG,RGS20,ATP1A3,HAP1,CBFA2T2,CACNA2D2,RCBTB2,MAML1,DAPK3,VPS13B,COQ7,MTSS1L,REEP2,FGF1,FHL1,FYB1,INPP5K,SRCAP,PCDH17,GRIK5,GRM8,RASSF8,MYT1,ENPP2,RETREG1,PPP2R2B,ZSCAN2,EMID1,SEMA6D,RASA3,SLC11A1,SLC12A4,COA1,SMARCD3,LIMCH1,SNCA,RPGRIP1L,TRIO,VGF,LAT2,KCNAB1,ITM2C" Drug 5114_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "RALGAPA1,AMT,APC,ADGRB2,CFLAR,TPP1,CSF1R,VCAN,SNPH,BRINP1,PARD6A,SPOCK3,EDNRA,EGFR,MBNL2,IRAK4,ETV1,ZNF589,B4GALNT1,MSL3,FAM69A,KCNN1,LSS,MAPT,TAGLN3,NFYA,P2RY1,PIK3R1,BCAS3,RAD51D,FAM184A,RGS4,SUGCT,FUZ,SNCA,RBM34,NXT2,SEPT8,KIAA1107,TCF4,SLC44A1,VGF,SH3GLB2,ZNF225" Drug 4551_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "APBB2,ARNTL,MYRF,BAIAP3,RAB28,NRXN3,AATK,CSNK1E,PDE4DIP,MFAP3L,SGSM2,CHRDL1,EXOG,EDIL3,EDNRA,PLXNC1,AASS,TNK2,MRNIP,DENND2A,SRCAP,MSL3,TJAP1,MAPT,MX1,NF1,CNOT4,SLC11A2,PLXNB1,POLG,DCUN1D2,RPS6KA2,MYH15,SPTAN1,ASTN2,SYNE1,TIAM1,TK2,AMACR,HIRA,PLPPR2,XRCC4,ZNF711,SPHK2" Drug 4104_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ALCAM,AMPD3,GAS7,ATP2B2,BAIAP3,CACNB4,NRG2,AATK,CSF1,RUSC2,CDON,RASGRP2,FGFR3,DCTN2,CSPG5,DLL3,GAD1,SIGLEC8,GNAO1,GSTM5,ATXN2L,VSIG4,SHISAL1,MATN3,ZNF862,NOVA2,NTRK3,PCDH8,PDE1C,MAPK7,ELOVL2,ZNF493,SBF1,SH3BP2,FRMPD1,SLC2A5,LIMCH1,SP4,SYP,EXOC7,WSCD1,SYNE1,TLR4,VSNL1" Drug 6648_UP "Clomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADORA1,SPARCL1,PPFIA4,ARHGDIG,ZSCAN18,BAIAP3,HAP1,CAPN3,CBS,EPS15L1,TPP1,MYRIP,NCOR2,CSF1,RIMS2,DBT,C2CD2L,EIF1,ZMYND10,ADAM28,RUNDC3A,LILRA2,CACFD1,ICA1,AFDN,ADAM22,MT1M,NRCAM,PALM,PDE4B,LRRN3,PRPH,DCHS2,KHDRBS2,CARF,SCN2B,ZNF334,ZSWIM8,UNC5B,DDN,PHF24,R3HDM1,VIPR2,LAMP5" Drug 4214_DN Propantheline bromide [50-34-0]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "PDE8B,MARCH3,SYNJ2,KRIT1,CBFA2T2,LY86,CSF1R,MFAP3L,EXOG,DTNA,DUSP9,CNNM1,EGFR,ZNF391,ETV1,DENND2A,MSL3,KCNMB4,SCIN,JAK2,PACRG,MATN3,TM6SF1,MGAT3,MN1,GIT1,RETREG1,GRAMD1C,CNTLN,TMEM231,FAM184A,BEND5,SUPT20H,FBXO11,PEX26,TMCC1,SPTAN1,ELOVL4,SYT1,TRIM2,RIMBP2,SSBP2,ZKSCAN5,KCNAB1" Drug 3781_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,ALK,AMPH,KCNAB2,GAS7,PDE8B,BMP7,GYG2,CFAP410,KALRN,CACNA2D2,CNTFR,ABCG1,LRIG1,PYGO1,ARHGAP24,SPOCK3,HIPK3,MBNL2,IRAK4,ING4,EZH1,ABCA8,FAM198B,KCNN1,KIFC3,MARK1,MGAT3,MMP16,ADAM22,NPTX1,NTRK2,NTRK3,PDE4B,PNMA8A,RXRA,STUM,RASA3,CPEB3,SNCA,NFASC,PHLDB1,COBL,PCDHA5" Drug 6611_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "LTBP4,SEMA7A,KCNAB2,APC,EPB41L5,GAS7,MPDZ,BMPR1B,KALRN,CAMK2B,RUNX1T1,CACNA2D2,ARHGAP22,CRY2,VCAN,EDIL3,SNX29,HIPK3,ERCC2,FGFR1,FOLR2,ALDH1L1,GNG4,ICA1,KCNJ5,KIFC3,NPR2,GPR85,PFKFB4,POU6F1,PPARA,WDR25,TMEM231,CARF,DOK5,SPTB,CDK19,SPART,COBL,MCF2L,TBCEL,RUNDC3B,AMACR,KCNAB1" Drug 3730_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "CDC14B,CDK13,CACNA1A,FAM189A2,LY86,CNTN1,HAPLN1,AATK,CSNK1E,ARHGAP24,DTNA,FAM13A,MBNL2,ANKMY1,FGFR1,SCARA3,PRELID3A,POLL,GRIK5,ICA1,SCIN,INPP5B,MAPT,MARK1,MMP16,NFIX,NPR2,PDPK1,PFKFB2,C1orf54,ZCWPW1,BTBD7,SOX15,ZHX3,IZUMO4,PLCB1,SYNE1,CHST8,TNS1,RPRM,VGF,XRCC4,NT5M,TIGD6" Drug 4383_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "GAS7,APOC1,PLA2G4C,AZGP1,BAIAP3,CAMK2B,HIP1R,CNN3,FAM149A,CABP1,ENTPD4,VCAN,SPOCK2,SPOCK3,CDON,ERBB2,NSG1,ZNF44,GFER,CSDC2,KCNN1,MGAT3,AFF1,MN1,ADAM22,MYT1,NEFM,PCBP3,PFKFB2,DUSP26,SERPINI1,PLCD1,RGS12,SLC11A1,SNAP25,ZC3H13,RGL1,WSCD1,RPGRIP1L,SLC19A3,DNAH7,R3HDM1,LAT2,SLC17A7" Drug 2267_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASPHD1,ADGRF5,LTBP4,TRMT9B,CDC42BPA,APC,MYOM1,CFLAR,BAIAP3,CAMK2B,RGN,KCNAB3,RAB33A,WHRN,VCAN,SPOCK2,SPOCK3,TMCC2,SHANK1,HIPK3,MBNL2,VPS13B,ERCC2,APC2,FGFR1,DLL3,SRCAP,GNAL,GRM8,TJAP1,ITGAM,MEF2C,MID1,NF1,LRP12,MINDY2,SNRK,RFX2,RPS6KA2,ASAP3,IQSEC2,PCDHA5,DICER1,AMACR" Drug 6570_DN Gly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF3,APBB2,APOC1,CDK10,SEMA4G,LDLRAD4,CFAP410,LRRFIP1,CSF1,SLITRK5,GREB1,ARHGEF4,SPOCK2,DTNA,STX2,SPEG,FGFR1,BAIAP2,SEMA4D,FLT1,CINP,GCNT2,COPS8,POLL,ELOVL5,SHISAL1,MAPT,NDP,RNASEL,SH3BP2,CNKSR2,SIRT2,KBTBD4,BTBD7,SPTAN1,PBLD,COBL,TK2,ZKSCAN5,RPRM,XRCC4,ZNF225,MAP3K12,KCNAB1" Drug 2792_UP Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADORA2A,ALCAM,KCNAB2,PPFIA3,CDK13,ADAM15,LDLRAD4,SLC16A4,CBFA2T2,SRSF11,AKAP7,CNTNAP2,MBNL2,HSD17B14,ZNF589,EFCAB2,MSL3,HAS2,HLF,ICA1,TJAP1,KIT,MMP16,ADAM22,NF1,CDK18,PDE1C,PPP5C,PRKAR1B,CCDC40,RGS12,ASAP3,CCDC88A,SLC11A1,KIAA1107,PCDHA5,DICER1,TRIO,TRO,REEP1,TFIP11,NT5M,ITM2C,ST7" Drug 5443_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADCY6,AP2A2,BIN1,APC,THSD7A,SULT4A1,CPS1,CSF1,CNTNAP2,DCAF4,INTS1,HS3ST2,FRY,TNK2,HPCAL4,FOXF2,DLL3,GATM,GFER,PRUNE2,PCLO,HAS2,ICA1,MAP4,MATN3,KITLG,ADAM22,NTRK3,PCDH9,PFKFB2,PTPRO,ENOX1,FAM214B,HECW1,PEG10,ZNF423,ARC,TCF4,HEY1,TRPM2,UCHL1,KCNAB1,ITM2C" Drug 3426_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,CDC42BPA,APBB2,APC,SLC4A4,MTMR2,BAIAP3,CBFA2T2,SULT4A1,RUSC2,HSD17B14,ERCC2,IQCG,ALDH1L1,TDRKH,STON1,IL6ST,INPP1,KCNH2,KCNN1,LAMA2,MATK,MIA2,SLC11A2,PLCD1,PPARA,ELOVL2,ZSCAN32,RGS3,SUPT20H,RASA3,ZBTB43,MCF2L,TBCEL,IQCE,WSCD1,SIN3B,SZT2,PCDHA6,ZKSCAN5,VIPR2,LMF1,KCNAB1,MPPE1" Drug 316_UP flufenamic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "KDM5D,ALK,BIN1,GAS7,DNAH17,GYG2,BAIAP3,CACNA1A,CH25H,STOML1,OSBPL3,PDE4DIP,HDAC9,DAPK1,GIT2,HEPH,ING4,HSD17B14,STX2,CDKL3,BAIAP2,NSG1,BRD8,MCHR1,PTPRT,NCKAP1L,KIFC3,MBP,NPY,NPTX1,FXYD1,HYDIN,PRODH,ZCWPW1,RFX2,RGS12,FNDC3A,SLC8A1,NMNAT2,SYN1,TCF4,DNAH7,THRA,VIPR2" Drug 2725_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "FGD2,APBB2,PLA2G4C,ADGRB1,CACNA1G,LDLRAD4,CAMK2B,VAX2,SULT4A1,CRY2,ABCG1,CRYM,DZIP3,DCAF4,SPOCK2,KLHL3,TMCC2,MAMLD1,PLXNC1,VPS13B,RASGRP2,DLC1,FGFR1,BAIAP2,GALC,ADAM28,SPACA9,TJAP1,KIT,SCAMP5,MYO7A,OPRL1,PFKFB4,PLCD1,CEP41,VPS13C,ST6GAL1,KIF13A,SOX15,SYNE2,CHST8,KLC2,ZBTB38,SLC30A3" Drug 3671_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADD2,ANK2,PPFIA4,PDE8B,SLC4A4,DLGAP2,ARHGAP22,STOML1,AKAP6,AKAP12,GREB1,DAPK3,HEPH,MFAP3L,EDN1,ZNF589,SIGLEC8,NEU3,ALDH1L1,GNAL,PADI2,C2orf72,INPP5B,MYO7A,NF1,PFKFB2,MTRF1L,STRN3,PPP2R2B,C1orf54,ZMAT4,RFX2,RGS12,SUGCT,EMID1,KCNIP1,SLA,SPTB,TNS1,TRIO,VIPR2,SPHK2,KCNAB1,AP3B2" Drug 2246_UP Isoniazid [54-85-3]; Up 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AP2A2,ADGRF5,AMPD3,AMPH,CDC42BPA,SLC4A4,ADAM23,BAIAP3,CALB2,CBARP,ASIC3,SULT4A1,CRMP1,DNAH9,EDN3,SEMA3D,MBNL2,MTSS1L,AGAP2,FYN,ZNF44,SIGLEC8,SRCAP,GFER,CSDC2,GNAL,IRAK3,MATN3,MYT1,NNAT,TMOD2,LRP12,KLHDC8A,FRMPD1,CPEB3,NLGN1,PKNOX2,SLC9A5,CXXC4,SLC30A3,NT5M,DNALI1,EPM2A,KAT6A" Drug 6725_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADRA1D,CDC14B,ARHGDIG,PDE8B,ATP2B2,KIF1A,ADAM23,LDLRAD4,SEPT7,VCAN,CNTNAP2,BRINP1,CDON,FCF1,AASS,ING4,MTSS1L,EZH1,PDLIM5,TRAF3IP2,SIGLEC8,STON1,LPAR4,NF1,PDE4D,PIK3R1,PRKAR1B,MAP6D1,FRMPD1,FBXO11,SNCA,TSNAXIP1,ARHGAP26,RBM26,THRA,TNS1,VIPR2,LMF1,WIPF1,XRCC4,EVI5,ACTR3B,AAAS" Drug 2349_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADGRF5,BEGAIN,APOC1,SEMA4G,ARRB1,CDK13,KIF1A,BMP7,CAMK2G,CPS1,SEC31B,VCAN,PDE4DIP,KIAA0753,SGSM2,TMCC2,DTNA,MRNIP,COQ7,NCALD,F5,PRKAG2,DLL3,SEPT9,ELOVL5,INPP1,JAK2,MAP4,NELL2,NF1,NINJ2,NPR2,OCRL,NLE1,PLCD1,TMEM231,RET,RGS12,SAFB,CNKSR2,KDM4C,DBNDD2,TSPYL2,SEPT8" Drug 7495_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,APBB2,APOC1,CDK10,ARRB2,SLC4A4,EIF4G3,ST3GAL5,CFAP410,CAMK2B,CBFA2T2,RAB26,PPP6R2,DMPK,DYNC1I1,APH1A,AASS,COQ7,CDKL3,ZNF589,TRMO,CINP,FYN,DENND2A,SRCAP,POLL,SCIN,LIFR,KCTD15,PRPH,TMEM231,SBF1,FAM214B,PDZD2,TCF4,HIF3A,LMF1,TRIM9,MAP3K12,EMSY,EVI5,PLSCR4,ST7,DPF3" Drug 6641_DN Khellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "APOC1,CDC14B,CDK13,DNAH17,KIF1A,ST3GAL5,CACNA1I,CHN2,ABCG2,WHRN,NCOR2,VCAN,CNTNAP2,MFAP3L,CNNM1,TNK2,IGSF6,ZNF549,CDKL3,CORO2B,ST3GAL6,TRMO,ZNF44,DISC1,POLL,LPAR4,KCNJ5,LSS,MAPT,MEIS1,AFDN,LYRM9,NF1,NPR2,GRAMD1C,SAMD9,ASAP3,ZNF415,TROVE2,KLHL4,TK2,TRIO,WIPF1,ZNF32" Drug 5207_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NME5,APC,PPFIA3,MARK4,N4BP2L1,CFLAR,KSR1,GYG2,CACNA1I,BAIAP3,USP2,ARHGAP33,NCOR2,CNTNAP2,PHF14,PARD6A,EGR3,EPHB1,TRMO,ADAMTS13,GRM8,GSTM5,GUCY1A1,KCNB1,KCNN1,NOVA2,NTRK2,PFKFB2,SNRK,ZCWPW1,RGS12,RNASE1,PEX26,CXXC4,SNAP25,SOX3,ZC3H13,RGL1,PHLDB1,PLCB1,ARC,SYN2,TPM2,CHST5" Drug 3666_DN Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "CDC42BPA,APAF1,APC,ARRB2,SCAPER,ARHGEF1,CACNA2D2,TAOK2,ARHGAP22,LHX2,NCOR2,SLITRK5,DAPK3,CDON,IRAK4,FGF1,OGA,TJAP1,KCNB1,MBD1,SCAMP5,TAGLN3,NFYA,RETREG1,SLC25A23,MAPK7,PTPRN2,RAD51D,ENOX1,GAL3ST4,GTDC1,RXRA,FAM102A,ST6GAL1,IFT122,IQSEC2,SS18,COBL,ASTN2,TRIM2,CHST8,AMACR,ZKSCAN5,NT5M" Drug 7232_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,AMPD3,GAS7,PPP4R4,RASL11B,ATP1A3,CA4,CAMK2B,ARHGEF2,TAOK2,CSF1,CYBB,FRY,TNK2,FHL1,ALDH1L1,HNMT,INPP5B,KIT,KPNA5,MAN2A2,KITLG,MITF,NEK1,NF1,CNOT4,PCDHGC3,PLCD1,PPP5C,ZFHX4,SCN8A,ZNF821,SYBU,RCOR3,ZNF415,LHPP,SZT2,PHF24,SLC19A3,PCDHA6,PCDHA5,GPR161,TPM1,EPM2A" Drug 3261_DN Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ALCAM,SRPX,APLP1,FAM131A,PPFIA3,CA4,SH2B1,CRY2,CSNK1E,PPP6R2,TBC1D5,DAPK3,DBN1,ACOT8,RCAN1,ZNF589,DISC1,INPP5K,ZNF276,POLL,CLASRP,FICD,HNMT,TJAP1,MAP4,NEK1,NPTX1,FAM184A,GTDC1,RGS12,RPS6KA2,SBF1,ZNF821,RASA3,EPN2,SMARCA4,KDM4C,IQSEC2,LHPP,EXOC7,USP22,SIK3,SLC44A1,CABIN1" Drug 2555_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG3,ADRA1D,GAS7,NCOA1,SYNJ2,SCAPER,C5,LDLRAD4,CACNA1A,RCBTB2,STOML1,SIPA1L1,VCAN,ARHGAP32,CDON,PLXNC1,MRNIP,FGFR1,EFCAB2,PDLIM5,ZNF44,ERAP1,COPS8,MSL3,NCKAP1L,ATXN2L,MAP4,MEF2C,PDE4D,NLE1,RNASEL,SBF1,MRAS,CNKSR2,ELMO2,ARHGAP26,SPTAN1,PJA1,EXOC7,TNS1,CDK20,LMF1,GDPD5,PCBP4" Drug 2402_UP Chenodiol [474-25-9]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF1,BCAS1,ARRB2,CACNA1I,CAMK2B,STOML1,CNTN1,DBT,HS3ST2,MRNIP,AFF2,PDLIM5,INPP5K,POLL,PRUNE2,ICA1,KCNJ5,KHK,LAMA2,LSS,AFDN,NINJ2,SLC11A2,PDE4B,PIK3R1,ZSCAN32,RGS3,SEMA6D,SBF1,SEC14L1,ASAP3,SLC9A5,ZNF415,ZSWIM8,ATP10B,TROVE2,SS18,DNMBP,WSCD1,OBSL1,SSBP2,ZBTB14,ZNF225,UBE3B" Drug 5096_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADD2,FAM135A,TRMT9B,GAS7,APLP1,ATP2B2,NRP2,ST3GAL5,SCAPER,CAPN3,FOXN3,RAB26,IQCK,WHRN,CABP1,SH2B1,CRMP1,HAPLN1,CSF1,ARHGEF10,SUSD5,EXOG,C3orf18,SPEG,NRN1,PDLIM5,GRM8,SOX21,MMP16,DCHS2,SAMD9,SNRK,KCTD17,DZIP1,SLC4A3,BTBD7,ZBTB43,ASTN2,TAL1,TLR4,TNS1,TPM1,SLC30A3,KCNAB1" Drug 3899_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,ADRA1B,LTBP4,AMPD3,TAOK2,RAB33A,CNTN1,AKAP5,CYBB,PLPPR4,SHANK1,ECM2,SNX29,EDNRA,FRY,C3orf18,ERCC2,F5,PDLIM5,CAMKK2,GAD1,GRIK5,NXPH3,KCNH2,LSS,MEF2C,MID1,ADAM22,NNAT,NOVA2,PALM,ZSCAN32,RGS12,CARF,STUM,ST6GAL1,DOK5,IZUMO4,DOCK9,DICER1,TRPM2,FLRT2,LAT2,SENP7" Drug 4751_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADORA2A,AMPD3,SEMA7A,APBA2,PPP4R4,N4BP2L1,ADGRB3,CDH2,ASIC3,MYRIP,NECTIN3,CRMP1,CNTNAP2,RIPOR2,EDN1,RCAN2,PTK2B,ZNF589,AFF2,PRELID3A,FYB1,GATM,SRCAP,ATXN2L,SYNPO,KCNH2,ADAM22,NTRK2,ENPP2,NKAIN1,RFX2,RGS12,TCP11L1,EMID1,ASAP3,FAM214B,ZNF415,SOX15,ATP10B,SYT5,VIPR2,SLC30A3,ITM2C" Drug 2891_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADRA1B,AP2A2,AMH,APLP1,APOC1,CACNA1I,BAIAP3,LDLRAD4,CFAP410,ARHGAP33,TAOK2,ARHGEF6,SPOCK2,C2CD2L,DTNB,OPTN,ELN,C3orf18,HSD17B14,ERCC2,REEP2,AGAP2,FYN,SLC2A6,HNMT,ICA1,TJAP1,KCNJ5,MEF2C,MSR1,NOVA2,CCDC40,SCN8A,SLC11A1,BTBD7,PDZD2,ATP10B,DNMBP,TBCEL,SMG6,WSCD1,DOCK9,PDIA2,GDPD5" Drug 2716_UP Hecogenin [467-55-0]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF1,BEGAIN,APC,MARK4,ZSCAN18,BMP7,CACNA1I,SCARB1,SYNGR3,CDO1,NRG2,CRY2,FAM169A,PPP1R16B,PHF14,RIPOR2,DBT,KLHL3,SV2B,DUSP9,HSD17B14,FGFR1,FHL1,PDLIM5,GLYR1,MGAT3,NF1,CNNM2,CCDC40,ENOX1,GAL3ST4,RFX3,PLPPR3,SEMA6D,CPEB3,ST6GAL1,CNKSR2,TMCC1,DOK5,ZHX3,IZUMO4,SYT5,KCNE5,PLPPR2" Drug 5992_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,AK2,CDC42BPA,NUMB,CFLAR,LDLRAD4,CA12,LRRFIP1,ABI3BP,CSF1R,CNTNAP2,CTH,DTNA,ANKMY1,F8,KAT8,ZNF589,POLR1B,FGFR1,FAM49B,CNTRL,GRM8,IL6R,IL6ST,INPP5B,ITPKB,WDR25,PTCH1,MRAS,CXXC4,UNC5B,IQSEC2,SPART,CLASP2,TROVE2,CEP68,TTBK2,PHLDB1,CHST8,TK2,CABIN1,ZFP37,FTSJ1,KCNAB1" Drug 3754_DN Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,AK2,DOC2A,AMPD3,CDC42BPA,SYNJ2,SOCS6,RAB28,AKAP7,CSNK1E,MBNL2,STX2,DCTN2,CGREF1,TRAF3IP2,GLYR1,GPD2,HSF2,INPP5B,LIFR,MAPT,MX1,NF1,CNOT4,LRP12,SAMD9,MCMBP,TCP11L1,RPS6KA2,RXRA,NLGN1,SNCA,PEG10,LHPP,FBXW11,SMG6,TMPO,TNS1,HIRA,LAT2,SPHK2,KAT6A,TIGD6,RNF170" Drug 7532_DN CP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AK2,FAM135A,PPFIA3,CFLAR,MAGI1,B4GALT6,LHX2,HOMER3,BAG4,ELN,COQ7,DLC1,TMEM8B,MALT1,LYVE1,GLYR1,NXPH3,ATXN2L,HSF2,ICA1,JAK2,NPR2,PALM,PCDHGC3,KCTD15,SMIM7,MINDY2,PTPRG,ZDHHC14,NEK11,TCP11L1,RPS6KA2,SH3BP2,SLC6A8,TROVE2,THSD1,PCDHA6,SLC44A1,CDK20,TRO,FAM155A,LMF1,XRCC4,EPM2A" Drug 6014_UP Pivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "APC,RASL11B,CFLAR,SCAPER,BAIAP3,CA4,CA12,CACNB4,PTBP2,RCBTB2,WHRN,CSF1,VCAN,TMCC2,DMPK,DTNA,HIPK3,COQ7,ZNF391,GFER,PCLO,ATXN2L,ICA1,SHISAL1,KCNJ5,KCNN2,TM6SF1,MID1,RETREG1,PLCD1,PURG,PPARA,MAPK10,GRAMD1C,RELN,TCP11L1,SH3BP2,CPEB3,PIK3R5,RUNDC3B,TRPM2,SLC17A7,FAM13C,JPH3" Drug 3750_DN Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ALK,AMPD3,ARHGEF2,B4GALT6,TPP1,ABCG2,AKAP7,NCOR1,CSF1,CNTNAP2,RCAN1,STX2,ERAP1,ARFIP1,GFER,MSL3,CACFD1,RASSF8,IL6ST,JAK2,MAP4,MAPT,MX1,NF1,CNOT4,PLCD1,PPARA,PRKAR1B,GRAMD1C,CNNM2,ZSCAN32,ENOX1,SCN8A,DZIP1,FAM214B,SNCA,ZHX3,IQSEC2,PHLDB1,ARC,EXOC7,KIAA1107,VGF,DPF3" Drug 5595_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,NME5,BIN1,CACNA2D2,QKI,AATK,CNTNAP2,GREB1,SEC14L5,RASSF2,ARMCX2,SV2B,ECM2,MBNL2,EGR3,VPS13B,CAMKK2,OGA,TRAF3IP2,GLYR1,NXPH3,JAK2,MAPT,NELL2,NOVA2,OPRL1,PDE1C,PIK3R1,PLCL1,LRP12,MAPK10,KCTD17,TCP11L1,RASA3,SGK1,CPEB3,CCDC88A,COA1,MYH15,SNCA,SPP1,R3HDM1,FAM155A,UBE3A" Drug 5533_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ABHD6,AP2A2,AK2,PPP4R4,NCOA1,SLC4A4,RIPK1,ST3GAL5,SYNJ2,SCAPER,SLC25A14,ABI3BP,CREM,ABCG1,CSNK1E,KIAA0586,VPS26C,TRMO,TDRKH,BTN2A1,KCNF1,KCNQ3,KHK,MAP4,MPP2,MSI1,ADAM22,SETD4,SMOX,RGS3,SBF1,PREX2,SMARCA4,IFT122,ZBTB43,POGZ,ARHGEF9,ASTN2,TRIM2,PIK3R5,NPL,MPPE1,KAT6A,RNF170" Drug 6078_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "RALGAPA1,SEMA6A,PRX,ASPA,CHRNA4,CYBB,SPOCK2,EDN1,LRRC17,REEP2,FGF1,SRCAP,PCDH17,LPAR4,GRB10,ADAMTS13,GRIK5,AP4S1,ATXN2L,ICA1,KIT,SMAD1,MYO7A,NFIX,NTRK2,TREM2,CDK18,PDE4A,ENPP2,PFKFB2,PPP5C,CEP41,SAMD9,C1orf54,RGS12,EMID1,SLC2A5,SLC11A1,DOK5,CUX2,TRPM2,PDIA2,WIPF1,SLC30A3" Drug 2158_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,ADD2,APAF1,SEMA4G,FUBP1,CLDN10,PICK1,MYRIP,RIPOR2,DBT,EIF1,F5,KAT8,PDLIM5,CAMKK2,SIGLEC8,INPP5K,ALDH1L1,ZNF276,HPGDS,GSN,PADI2,ICA1,L1CAM,MAP4,ZNF862,PDE4A,PFKFB2,PPP5C,DEF8,PTPRN2,SUSD4,RFX2,SLC2A5,BTBD7,DOP1A,SPTB,TSPYL2,SEPT8,MCF2L,TNS1,RUNDC3B,LMF1,PRDM10" Drug 5617_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,CD86,RAB33A,CABP1,NCOR2,RASSF2,RUSC2,SPOCK3,DMD,HS3ST2,APC2,FGFR1,TMEM8B,SRCAP,POLL,GRIK5,GRIN2C,ATXN2L,KCNJ5,KCNQ3,TAGLN3,PCBP3,PDZRN4,C19orf57,CNNM2,CNTLN,CCDC40,GAL3ST4,RFX3,ASAP3,CNKSR2,SLA,PKNOX2,TSNAXIP1,PEG10,MCF2L2,ATP10B,RGL1,PHLDB1,DOCK9,CRTC1,DNAH7,CHST5,XRCC4" Drug 221_DN 17-AAG; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADD2,BRAP,ALK,APBA2,ARNTL,PLA2G4C,CHN2,CLIP3,AATK,CSF1R,KLHL3,DMPK,DYNC1I1,FAM13A,EIF4G2,TNK2,ANKMY1,PTK2B,ZMYND10,FLNC,FYB1,GNAO1,SOX21,FAM107A,NXPH3,VSIG4,MARK1,MMP16,NF1,NOVA2,PLCD1,MAPK3,RASGRF1,GAL3ST4,EMID1,LIMS2,SIRT2,SNCA,HECW1,SPART,TROVE2,ADGRL3,ZNF32,HPS4" Drug 2326_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADRA1D,PPP4R4,GYG2,BAIAP3,CFAP410,CA4,CA12,RAB33A,SULT4A1,CRMP1,SIPA1L1,RCAN1,EDNRB,FEM1B,ZNF589,AFF2,ALDH1L1,POLL,GRIK5,GSN,TJAP1,MAP4,MIA2,NF1,GPR85,PFKFB2,PPP2R2B,MAPK7,ELOVL2,ZDHHC14,EMID1,SBF1,FRMPD1,PREX2,FAM214B,SYN2,SZT2,DOCK9,CABIN1,PIK3R5,FLRT2,XRCC4,GDPD5" Drug 3016_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C3orf14,CDC42BPA,APAF1,SYNJ1,SYNJ2,CHRNA4,FAM149A,PPP1R16B,BRINP1,TOM1,E2F5,MBNL2,AASS,COQ7,CDKL3,DLC1,EFCAB2,SIGLEC8,LILRA2,PADI2,MAPT,AFF1,AFDN,NINJ2,NNAT,CNOT4,NPR2,PPARA,PTPRB,ZDHHC14,TCP11L1,SCN2B,SEC14L1,FRMPD1,NLGN1,DZIP1,ANKRD6,SPART,RPGRIP1L,OBSL1,THRA,CDK20,TRO,JPH3" Drug 2498_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADRA1D,AP2A2,BIN1,APAF1,APBB2,CASK,SLC4A4,N4BP2L1,RUNX1T1,PLAA,CNTN1,AKAP7,IQCK,SH2B1,ABCG1,DGKG,CELSR3,EIF4G2,CDKL3,F5,PTK2B,ST3GAL6,KAT8,USP19,PADI2,TJAP1,ZNF862,PLCD1,NECAB2,POU6F1,PTPRN2,ZNF821,SH3BGR,PEX26,ARHGEF9,SYN2,EXOC7,PDLIM2,ADGRL3,KIAA1107,CHST8,ZNF34,FZD3,UBE3B" Drug 2535_DN Streptozotocin [18883-66-4]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADRA1D,MTUS1,AMH,KCNAB2,APC,FAM131A,ADGRB1,BMP7,TAOK2,PICK1,SH2B1,PDE4DIP,ARHGEF4,MBNL2,RASGRP2,MTSS1L,ZNF44,SEPT9,SRCAP,PRUNE2,LILRA2,CACFD1,GUCY1B1,MAPT,AFDN,NNAT,PDE4A,PLCD1,LRRN3,KHDRBS2,CCDC92,SLC11A1,CXXC4,MYH15,SNCA,ATP10B,JMJD6,SYT5,TAL1,TNS2,THRA,TRIO,FLRT2" Drug 2917_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "APBB2,GYG2,LDLRAD4,CA8,THSD7A,DCAF4,ZNF337,SPOCK2,DTNB,TNK2,APC2,ETV1,FCGRT,FGFR1,BAIAP2,AFF2,PDLIM5,SIGLEC8,SEPT9,CSDC2,GNG4,GRIK5,ATXN2L,KCNJ5,MMP16,OPRL1,PDE1B,NLE1,PLEC,SLC25A23,NECAB2,PRPH,MASP1,BCAS3,CCDC40,SLC11A1,TMCC1,SPTAN1,IQSEC2,EXOC7,CHST8,TK2,ICAM5,FAM155A" Drug 6629_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,AP2A2,PPFIA4,APC,DNAH17,ARMC8,AATK,CSNK1E,ARHGEF4,MFAP3L,SGSM2,DMPK,SEMA4D,DISC1,CACFD1,GRM8,KIF2A,MAPT,MBD1,AFDN,NF1,SLC11A2,SETD4,PDE4D,MAPK7,CNNM2,ZCWPW1,KIRREL1,ZC3H14,ASAP3,FUZ,IQSEC2,DDN,KIAA1107,TCF4,TIAM1,OSBP2,LMF1,WIPF1,WNT7A,XRCC4,NDRG4,NT5M,NAV3" Drug 7174_DN Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "MTUS1,MARCH3,EIF4G3,BCL7A,PTBP2,SOCS6,TAOK2,CREM,DCAF8,SPATA2,VPS26C,POLR1B,INPP5K,PRRC2B,GPR37,MUM1,RBPJ,IL6ST,MAP4,MIA2,NEK1,NF1,SETD4,SLC25A23,POLG,MAPK3,NKAIN1,FBXW7,PEX26,SMARCC2,ZHX3,ZSWIM8,ZBTB43,SS18,STXBP1,COBL,ANKRD28,ANKRD12,CHST8,CABIN1,LMF1,ZNF24,UPF3A,EPM2A" Drug 5793_DN Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AP2A2,ARHGEF6,CPS1,CSF1,PDE4DIP,DBN1,C2CD2L,HIPK3,ACSL4,BAIAP2,CINP,GAD1,TMEM8B,DISC1,GSN,TJAP1,MATN3,MT1M,ZNF862,NF1,PFKFB3,NLE1,MINDY2,ELOVL2,PTN,RIPOR1,TMEM231,BEND5,KIRREL1,AMBRA1,BTBD7,KDM4B,ZBTB43,LHPP,TROVE2,ARHGEF9,SYT1,MCF2L,TCF4,TIAM1,TK2,WNT7A,NT5M,GAN" Drug 2226_DN Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF3,APBA2,KCNAB2,RGS20,PLA2G4C,SYNJ2,GYG2,SLIT2,PICK1,ABCG1,CSF1R,PPP6R2,SEC14L5,TMCC2,CDON,EZH1,FHL1,FAM49B,DISC1,SEPT9,SRCAP,SPACA9,GRIK5,MATK,MEIS2,MMP16,NF1,PPP2R2B,ZCWPW1,SUPT20H,PREX2,DOK5,ZHX3,ARC,MTCL1,TBL1X,ZKSCAN5,FAM155A,FLRT2,PLPPR2,GDPD5,HPS4,KCNAB1,KAT6A" Drug 4724_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASPHD1,ABHD6,ADRA1D,AK2,BIN1,CDC14B,RGS20,MTMR3,EPS15L1,AKAP7,WHRN,CRY2,CSF1R,BRINP1,SPOCK3,AASS,ERCC2,ZNF589,FHL1,FYB1,GFER,GNG4,PRUNE2,DHX35,KCNN1,KPNA5,MGAT3,GIT1,NF1,NNAT,RETREG1,PTN,ZDHHC14,FAM214B,PKNOX2,KIF13A,SPTAN1,ATP10B,VLDLR,XRCC4,MAP3K12,DNALI1,HPS4,TIGD6" Drug 5080_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AGT,ALK,PPFIA4,KCNAB2,RGS11,RGS9,CACNA2D2,CHN2,CLTB,WHRN,CABP1,SUSD5,PDE4DIP,RIMS2,EDNRB,MTSS1L,PIPOX,AFF2,CAMKK2,CGREF1,GFER,CACFD1,IRAK3,MAN2A2,ADAM11,AFDN,ADAM22,MYT1,P2RY1,PALM,LRRN3,PTPRB,PID1,RGS4,RGS12,KCTD17,FBXW7,MRAS,PHLDB1,SLC44A1,THRA,TNS1,UBE3A,SEMA3B" Drug 2817_DN Gelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "PPFIA3,CDK10,PPP4R4,ARHGDIG,ARRB1,RIPK1,ST3GAL5,KYAT1,USP2,PLEKHB1,TAOK2,HOMER3,COL4A5,SLC4A8,CREM,CSNK1E,LYPD1,SGSM2,FGFR1,BAIAP2,IQCG,TXNL4A,HNMT,DHX35,KCNH2,MAN2A2,MAP4,MATK,NFYA,NPR2,MBOAT7,FSD1,WDR25,RIPOR1,RAD51D,ROBO1,ZNF821,SPTAN1,SEPT8,MCF2L,TBL1X,ZKSCAN5,GDPD5,PHTF2" Drug 1468_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "APBA2,BCAS1,PPP4R4,CFLAR,ST3GAL5,SCAPER,RUNX1T1,SEPT7,ASIC3,NECTIN3,FAM169A,EDNRA,CNTRL,C2orf72,TJAP1,KCNH2,NEK1,NPY,MAPK7,CNNM2,RGS12,ASAP3,FBXO11,PPP4R3A,SLC9A5,LIMCH1,RBM34,ERC1,SPART,PHLDB1,PLCB1,FBXW11,TBL1X,CRTC1,HIF3A,DNAH7,DICER1,CHST8,HEY1,TLR4,CABIN1,WIPF1,LAT2,EPM2A" Drug 3342_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NME5,SEMA6A,GAS7,N4BP2L1,CACNA2D1,HAP1,ARHGEF2,CHN2,NRG2,VCAN,GREB1,SNPH,EDN1,MBNL2,FAM198B,DLC1,FHL1,GPR37,IL6ST,LAMA2,MAPT,MSR1,TAGLN3,NF1,PDE4B,PLTP,PDZRN4,SAMD9,SNRK,ZMAT4,RGS12,FNDC3A,CNKSR2,EPN2,ZC3H13,ARHGAP26,ATP10B,SSTR2,DMXL2,GPR161,TRPM2,WIPF1,DNALI1,SEMA3B" Drug 2557_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "PKP4,PPP4R4,MPDZ,KSR1,MYRF,THSD7A,SLC16A4,CDH2,TAOK2,STOML1,HOMER3,CNTN1,COL9A3,ABI3BP,CSNK1E,PDE4DIP,SLITRK5,USP6NL,DGKG,MFAP3L,EDNRA,RASGRP2,RRAGB,OLFM1,DCTN2,ADAM28,GPD2,PRUNE2,GPER1,TJAP1,KPNA5,MAPT,TAGLN3,PFKFB4,PLEC,PTK2,RET,RASA3,SLC11A1,SNCA,ZC4H2,TRIM2,CRTC1,GAN" Drug 4595_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "PKP4,CDK10,MARK4,NRP2,TPP1,HOMER3,ENTPD4,CSF1R,SGSM2,EDNRA,IRAK4,ING4,MRNIP,FGFR1,SCARA3,CINP,FYB1,INPP5K,GLYR1,TDRKH,STON1,ATXN2L,SHISAL1,MAPT,MMP16,ZNF862,CLDN11,PLCD1,RAD51D,GAL3ST4,DCUN1D2,ZNF821,DZIP1,ANKRD6,PEX26,ZNF667,ZHX3,ASTN2,GPR161,TK2,VGF,WIPF1,TFIP11,MAP3K12" Drug 3910_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ASIC1,ADORA1,ADORA2A,ALCAM,BIN1,APAF1,GAS7,ARHGDIG,NUMB,SLC4A4,N4BP2L1,LDLRAD4,ARHGEF6,AATK,GREB1,ARHGEF4,SEC14L5,EDN3,RASGRP2,FGFR1,PDLIM5,KHDRBS3,TMEM8B,GLYR1,POLL,GRM2,HSF2,L1CAM,MAPT,MYT1,MAPK7,SNRK,ZDHHC14,RNASE1,SLC2A5,ARHGEF40,KDM4B,PCDHA5,TPM2,LAT2,SLC30A3,HPS4,PARP11,ST7" Drug 2564_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NDRG2,AP2A2,ARHGDIG,PROM1,CFAP410,THSD7A,HIP1R,WHRN,COL9A3,RIMS2,RIPOR2,DTNB,FAM13A,TNK2,SRPK3,COQ7,RASGRP2,ANKMY1,CORO2B,CAMKK2,GAD1,ALDH1L1,ADAM28,PADI2,TJAP1,KIT,MAPT,SLC25A23,PTPRN2,GAL3ST4,ZNF821,PREX2,SLC11A1,HECW1,ARHGAP26,SPTB,SPART,DNMBP,DOCK9,PARD3,TUBB1,LAT2,SENP7,JPH3" Drug 440_DN "W-13, hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "BRAP,AMT,CDC42BPA,GAS7,BACH1,SLC25A14,ENTPD6,LHX2,STOML1,AATK,ARHGEF10,DZIP3,USP6NL,EXOG,FCF1,RGS17,STX2,SCML2,FGFR3,PRKAG2,MALT1,RUNDC3A,LILRA2,BTN2A1,RNFT2,MAPT,ADAM22,MYT1,NACA,NELL2,NPR2,ENPP2,PLCD1,POLG,SPART,SYN1,TACC1,TNS1,TRIO,HIRA,PDIA2,WIPF1,MPPE1,EPM2A" Drug 6090_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "RALGAPA1,SPARCL1,ALK,PLA2G4C,BAIAP3,CALB2,FOXN3,SULT4A1,CRYM,CSF1,SPOCK2,DBT,DNAH9,EDN3,TENM1,F5,FGFR1,FOLR2,CAMKK2,FYB1,SRCAP,GSN,KCNJ5,MBP,MYT1,PALM,PDPK1,RETREG1,PPP5C,SAMD9,ZDHHC14,ZMAT4,SLC9A5,SOX15,PEG10,ARHGAP26,TACR1,R3HDM1,PIK3R5,CHST5,WIPF1,SLC30A3,SLC17A7,KCNAB1" Drug 7505_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ABHD6,NDRG2,DOC2A,CDC42BPA,N4BP2L1,CFAP410,CRY2,MFAP3L,DTNA,HIPK3,FEM1B,EGFR,SPEG,VPS26C,EZH1,SCARA3,GALC,SEPT9,ITPKA,JAK2,IPO5,MMP16,SLC11A2,CCSER2,POLG,PPP5C,MAPK7,CARF,TCP11L1,SGK1,ASAP3,PEX26,KDM4B,IZUMO4,IQSEC2,ANKRD12,IQCE,TRIM2,CHST8,TK2,BEX4,CDK20,ZNF45,MAP3K12" Drug 3995_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "NME5,AK2,APBB2,GAS7,PDE8B,ALDH7A1,SYNJ2,CHN2,NRXN3,QKI,HOMER3,CPS1,AATK,CSNK1E,ARHGAP24,GIT2,DBT,LYPD1,MTSS1L,DENND4A,FGF1,FGFR1,FYN,GHR,JAK2,MN1,NDP,RETREG1,MAPK7,ZCWPW1,KIRREL1,FBXW7,MAPK12,FBXO11,ST6GAL1,TMCC1,ARHGAP26,DDN,TROVE2,SS18,ARHGEF9,KIAA1107,BHLHB9,SSBP2" Drug 2380_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ABHD6,ALK,DOC2A,AMT,STX16,N4BP2L1,CAPN3,CAST,CD86,FOXN3,ARHGEF10,DTNA,E2F5,FEM1B,FCF1,ANKMY1,F5,FCGRT,ANKFY1,TRAF3IP2,SEPT9,ALDH1L1,ZNF276,GLYR1,LILRA2,INPP5B,ITGAM,IPO5,LIG4,MEF2C,ZNF862,OGG1,PDE4A,PFKFB2,STUM,SH3BP2,FNDC3A,SNCA,ARHGAP26,DBNDD2,DDN,ZKSCAN5,UBTF,ST7" Drug 7421_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AK2,SEMA6A,AMH,APBB2,CDK10,ARRB1,ATP6V0A1,MPDZ,ST3GAL5,CFAP410,PLEKHB1,STOML1,QKI,AKAP7,VCAN,DZIP3,GIT2,DTNA,TOM1,HIPK3,EIF5,ING4,B4GALNT1,SRCAP,CSDC2,MSL3,POLL,LPAR4,SPACA9,RASSF8,INPP5B,MMP16,PDE1C,PTPRB,RGS12,SLC2A5,MAPKBP1,SNCA,SPTAN1,TMEM121,PIK3R5,UBE3A,HPS4,PHTF2" Drug 2638_UP Mimosine [500-44-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ADD2,AK2,BIN1,APBB2,CDK13,CFLAR,SYNJ2,LDLRAD4,CA4,CACNA2D1,CAMK2B,CDH2,SULT4A1,HINFP,JAKMIP2,SHANK1,SLC12A6,TENM1,ELN,ZNF589,SEMA4D,GAD1,TMEM8B,MALT1,GNAL,IL6R,KCNJ5,LSS,NELL2,OPRL1,PPP2R2B,CEP41,RGS12,SEMA6D,ANKRD6,SMARCD3,SPTAN1,IQSEC2,EXOC7,VLDLR,WIPF1,SLC30A4,SLC17A7,PHTF2" Drug 2276_UP Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "CDK13,SYNJ2,DLGAP1,NCOR2,OSBPL3,CNTNAP2,BRINP1,EDNRA,PLXNC1,PIPOX,NRN1,REEP2,CORO2B,FGFR3,SCARA3,DCTN2,FYN,GPR75,LPAR4,GRIN2C,GRM8,IFI16,MEF2C,AFDN,NF1,PFKFB2,PLCB2,LRRN3,PTPRB,KHDRBS2,ZNF821,MRAS,FRMPD1,ASAP3,NLGN1,SLA,SLC9A5,HECW1,ARHGAP26,EXOC7,TBCEL,TRPM2,FAM155A,NT5M" Drug 7017_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "AP2A2,ALCAM,CDK13,SCAPER,BAIAP3,CBFA2T2,ARHGEF10,SOCS5,RASSF2,INTS1,ARMCX2,DTNA,CDKL3,FECH,BAIAP2,FHL1,SEMA4D,GAD1,TXNL4A,RAB40B,SPACA9,HLF,ELOVL5,INPP5B,KCNF1,IPO5,LAMA2,MMP16,GIT1,MSR1,LYRM9,CNOT4,SETD4,CNNM2,RGS3,GSTCD,FBXW7,FBXO11,SNCA,LHPP,PCDHGA10,R3HDM1,ZBTB14,PHTF2" Drug 2118_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "ABHD6,BEGAIN,LGR5,PPP4R4,CA12,RAB28,QKI,NRG2,VCAN,SLITRK5,EGFR,PLEKHA1,STX2,PIPOX,ST3GAL6,SEMA4D,TRMO,PDLIM5,GLYR1,HNMT,MATN3,GIT1,NF1,GPR85,STRN3,NECAB2,PTPRB,SUSD4,RGS4,RGS12,SEMA6D,PKNOX2,ERC1,UNC5B,ZBTB43,LHPP,IQCE,CHST8,TIAM1,BCL2L13,VIPR2,SPHK2,MAP3K12,SEMA3B" Drug 6044_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "C1QTNF1,ALK,BIN1,AMT,APLP1,PLA2G4C,ATP2B2,SLC16A4,ARHGEF6,CNTNAP2,DGKG,DTNB,FRY,EGR3,ERBB4,CDKL3,ZNF589,GCNT2,GFER,GNAL,PRUNE2,GRM8,HNMT,TJAP1,MID1,TAGLN3,ZNF862,NEFH,PDE4D,PDZRN4,MINDY2,PPP5C,RGS12,NUDT11,KCNIP1,RASA3,SNAP25,KDM4B,ATP10B,TCF4,PCDHGA10,CHST5,TRO,LAT2" Drug 6089_UP Althiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "SEMA6A,AQP6,SEMA4G,CDK13,BAIAP3,CDO1,LY86,SNCAIP,CYBB,SPOCK2,HEYL,RCAN2,ABCA8,ZMYND10,ZNF44,SIGLEC8,GATM,SRCAP,GLYR1,PRUNE2,STON1,ADAMTS13,GRIK5,IRF8,C2orf72,KIT,MGAT3,ADAM22,MSR1,ZNF862,MYT1,NNAT,OGG1,PDE4A,C19orf57,RELN,PNMA8A,HKDC1,LIMCH1,ARHGAP26,PHLDB1,SYT5,TRIO,ADAMTS9" Drug 3371_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.94E-06 3.92E-01 2.43E-04 2.73E-03 44 198 "RALGAPA1,SYN3,ASIC1,LTBP4,APAF1,GYG2,BAIAP3,CAMK2B,CDH2,SULT4A1,AKAP6,EDNRB,IGSF6,APC2,PIPOX,F5,FLNC,ERAP1,NEU3,LYVE1,GNAO1,GPER1,TJAP1,IL6ST,ITPKB,KCNB1,KIF5A,TAGLN3,MX1,CEP41,SAMD9,WDR25,PTPRB,SH3GL3,FAIM2,KDM4B,HECW1,SPP1,PEG10,KIAA1107,HEY1,SLC30A3,SLC17A7,KCNAB1" Drug 5434_DN Piribedil hydrochloride [78213-63-5]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.15E-06 4.01E-01 2.48E-04 2.79E-03 43 192 "ASIC1,C1QTNF3,APC,CDC14B,KIF1A,MTMR2,BAIAP3,SOCS6,PLEKHB1,ARHGEF6,CNTNAP2,PPP6R2,DBN1,MFAP3L,DTNA,FCF1,CNNM1,EIF4G2,VPS13B,FGF12,GCNT2,GLYR1,RAB30,GPER1,CACFD1,ELOVL5,HSF2,KITLG,ADAM22,NFYA,ELOVL2,TMEM231,TCP11L1,ASAP3,TROVE2,NXT2,EXOC7,FBXW11,VIPR2,KCNK12,ZBTB14,SPHK2,RNF170" Drug 7489_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.15E-06 4.01E-01 2.48E-04 2.79E-03 43 192 "AP2A2,KIAA1324,LTBP4,APBB2,APOC1,ATP2A2,MTMR3,MTMR2,GYG2,SGCE,CRLF1,TAOK2,RAB33A,STOML1,COL9A3,MYRIP,CRMP1,CSF1R,RGS6,CTH,DAPK3,SPOCK3,DTNB,HIPK3,FEM1B,FGFR1,FHL1,DCTN2,FYB1,GLYR1,HAS2,MBP,KITLG,MMP17,PPP5C,PTX3,RGS3,EMID1,ZNF821,FNDC3A,BTBD7,RGL1,PIK3R5" Drug 2271_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.15E-06 4.01E-01 2.48E-04 2.79E-03 43 192 "ASIC1,NDRG2,LTBP4,AMPD3,BIN1,APBB2,ARRB1,CA12,KRIT1,CCNT1,ARHGEF2,MAGI1,PLEKHB1,LHX2,ABI3BP,GREB1,EDNRA,SRCAP,RAB30,GNG4,SPACA9,GRIK5,INPP5B,ITPKB,JAK2,KCNH2,KITLG,MMP16,ZNF862,CDK18,PLCD1,ZNF821,SUPT20H,SH3BP2,KDM4B,KDM4C,TROVE2,PHLDB1,KIAA0930,TNS2,THRA,UBTF,ST7" Drug 4711_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.15E-06 4.01E-01 2.48E-04 2.79E-03 43 192 "NME5,ALK,AMPD2,AMPD3,NRP2,CFLAR,CACNA1A,SEPT7,STOML1,CREM,SEC14L5,GIT2,DTNA,EGFR,EGR3,ING4,ENO2,ANKMY1,FHL1,DCTN2,FAM49B,ATP2C1,HLF,IL6ST,INPP1,ITGA7,RETREG1,MTRF1L,PPP5C,RELN,PTX3,TCP11L1,SYBU,SLC2A5,SLC9A5,SMARCD3,KDM4B,IZUMO4,CHST8,UBE3A,NT5M,SEMA3B,AP3B2" Drug CID000004624 6-OHDA Stitch 9.17E-06 4.02E-01 2.48E-04 2.79E-03 53 255 "ACHE,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,PRX,CALB1,CALB2,CCK,DNM1L,PPP1R1B,GAD1,LOXL3,MCHR1,GPR37,GRIA2,GRIN2C,GRIN2D,GRM2,GRM8,IL12A,PACRG,MAPT,NPY,OPA1,OPRL1,PDE4B,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,KLK6,RET,FBXW7,MAPK12,HSPA4L,SIRT2,SNCA,SST,SSTR1,SSTR2,SYN1,SYN2,MLST8,ZMAT3,TK2,UBC,SLC30A4,SLC17A7" Drug 4380_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.33E-06 4.09E-01 2.52E-04 2.84E-03 42 186 "DDO,APOC1,CFAP410,CDH2,CNTN1,RGS6,ARHGEF10,PDE4DIP,CNTNAP2,ELMO1,DTNA,LRRC17,APC2,KHDRBS3,FYN,GABRG2,PCLO,CACFD1,SOX21,HLF,KCNJ5,LMO2,LSS,MAP2,PCDH9,CDK18,PFKFB2,SERPINI1,SMOX,SMIM7,KCNIP1,SMPD3,SH3GL3,ASAP3,SLC2A5,FAM214B,BTBD7,KDM4B,ELOVL4,RGL1,SLC30A3,SLC17A7" Drug 2202_UP Gossypol [303-45-7]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.33E-06 4.09E-01 2.52E-04 2.84E-03 42 186 "AP2A2,CDC42BPA,APBB2,CLGN,CHN2,CNTN1,AKAP6,WHRN,SIPA1L1,CTH,RIMS2,FAM13A,EGR3,EIF5,PIPOX,REEP2,ST3GAL6,HPCAL4,FLT1,FYN,ZNF44,MBNL1,NNAT,P2RX7,ENPP2,NECAB2,POU6F1,PSD,RPS6KA2,CLIP1,ZNF821,PPM1E,EPN2,PKNOX2,SPTB,ATP10B,IQCE,PCDHA5,HEY1,FLRT2,LMF1,PLSCR4" Drug 6939_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.49E-06 4.16E-01 2.56E-04 2.88E-03 41 180 "APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CRLF1,WHRN,AKAP12,PDE4DIP,DOCK4,ARMCX2,JAKMIP2,TMCC2,OPTN,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MXI1,PCDH9,PDE4A,SERPINI1,RETREG1,PKIA,PRPH,SH3BGR,SH3GL3,SYBU,WDR47,SOX15,SPTAN1,RGL1,STXBP1,AGTPBP1,HEY1,BEX4,RUNDC3B,GDPD5,SLC17A7" Drug 1752_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; HL60; HG-U133A Broad Institute CMAP Up 9.49E-06 4.16E-01 2.56E-04 2.88E-03 41 180 "NDRG2,BIN1,EP400,ARRB2,DNAH17,MTMR3,CD86,LRRFIP1,CHN2,AKAP7,CREM,AATK,PPP1R16B,RUBCN,DOCK4,FAM13A,PADI2,PACSIN2,MAN1B1,MAN2A2,PDE4B,GPSM2,SMOX,PPP2R2B,PTK2,SATB1,SGK1,SLC11A1,ELMO2,KDM4B,ZSWIM8,SPTAN1,SAMSN1,STX1A,PLCB1,NSD1,SIK3,TRPM2,FLRT2,PLPPR2,PDSS2" Drug CID000004197 milrinone Stitch 9.56E-06 4.19E-01 2.58E-04 2.90E-03 36 150 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,PDE8B,ATP2A2,ATP2B2,ALDH7A1,CACNA2D1,CALM1,LRBA,PLCXD3,ENPP6,ATP2C1,GPT2,PLCD4,CIT,GUCY1B1,NPR2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PLCB2,PLCD1,PRKACB,GDPD2,SMPD3,FNDC3A,PLCB1,SYNE1" Drug 7179_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.60E-06 4.21E-01 2.59E-04 2.91E-03 40 174 "ABHD6,NME5,ARNTL,BMP7,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,ARMCX2,JAKMIP2,MBNL2,CDKL3,BAIAP2,FYN,CYP46A1,STON1,MXI1,NEK1,PCDH9,SERPINI1,PKIA,PRPH,SEC14L1,SH3BGR,SH3GL3,SYBU,WDR47,CCDC88A,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,AGTPBP1,HEY1,NPL,RUNDC3B,SSBP2,SLC17A7" Drug 4247_UP Piperine [94-62-2]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NME5,PKP4,CACNA1A,FOXN3,NRXN3,SUSD5,ERC2,DAPK3,SV2B,ECM2,EDN3,EPHB1,NCALD,ZNF391,ETV1,F5,PTK2B,FGF1,PDLIM5,ERAP1,SYT17,NEU3,PCDH17,CNTRL,IL6ST,LAMA2,SMAD1,MAP2,NRCAM,MTRF1L,PRKCB,PTN,MARCH1,KCNIP1,SH3BP2,CPEB3,SLC12A4,SP4,ASTN2,TBCEL,HIRA,WIPF1,KCNAB1,KAT6A" Drug 4375_DN U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AP2A2,ALK,AMPD3,BIN1,APBB2,NRP2,GYG2,CACNA1I,LDLRAD4,CAMK2B,SCARB1,HOMER3,CPS1,NCOR2,AATK,CNTNAP2,RIMS2,MFAP3L,HIPK3,TNK2,NCALD,DLC1,FGFR3,SRCAP,RUNDC3A,STON1,ATXN2L,NNAT,PDE4B,GPR85,PLCB2,LRP12,MAPK10,CNNM2,TRIM68,TCP11L1,ZBTB43,SAMSN1,KIAA0930,ZEB1,TK2,TPM2,TRPM2,PARP11" Drug 6819_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADORA2A,AMPD3,SEMA4G,ALDH7A1,SYNJ1,SCAPER,CA4,CLGN,CHRNA4,SULT4A1,LY86,NECTIN3,CPS1,VCAN,PDE4DIP,DCAF4,TMCC2,DTNB,HIPK3,HEYL,OPTN,EBI3,EGFR,ERCC2,ACSL4,AFF2,PCDH17,GRM2,GRM8,NXPH3,HNMT,INPP5B,KCNN2,KIFC3,MYO7A,RGS12,TCP11L1,FNDC3A,PKNOX2,NMNAT2,ARHGAP26,CLASP1,KCNAB1,KAT6A" Drug 2285_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "TRMT9B,AMH,CDC42BPA,APLP1,MARK4,SLC4A4,ATP2B2,N4BP2L1,NRP2,SCAPER,HIP1R,USP2,KCNAB3,AKAP6,WHRN,CSF1R,VCAN,ARHGAP24,BRINP1,MTSS1L,FOLR2,EFCAB2,FAM49B,OGA,GPR162,GPR75,GRM8,GSTM5,KIFC3,KIT,NF1,PFKFB2,CRTAC1,TCP11L1,SEMA6D,STUM,SLC2A5,ATP10B,JMJD6,ARC,EXOC7,PHF24,TRO,FLRT2" Drug 7521_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ABHD6,ADORA1,AP2A2,ALCAM,BIN1,APAF1,APC,APLP1,PPFIA3,CFLAR,CA4,FOXN3,WHRN,CREM,NCOR2,ANKMY1,FGFR1,BAIAP2,FOXF2,GNG4,GPER1,GRB10,AFF1,NNAT,DUSP26,LRP12,CNNM2,WDR25,RGS12,ZNF821,BTBD7,KDM4B,KDM4C,UNC5B,TTBK2,PHLDB1,IQCE,PARD3,CHST5,METTL3,KCNK12,ZNF24,GDPD5,ITM2C" Drug 2376_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,ADRA1D,SEMA6A,AMPD3,APAF1,CDC14B,ARHGDIG,ARRB1,DNAH17,GYG2,C5,CHRNA4,SPOCK2,DBT,OPTN,ELN,RASGRP2,FHL1,CELF1,FYB1,GNG4,BTN2A1,ATXN2L,JAK2,MN1,MYCN,MYO7A,NEK1,NF1,OPRL1,GPR173,FSD1,MAPK10,CNNM2,CRTAC1,DOP1A,PDLIM2,TBCEL,CRTC1,TEK,SSBP2,FLRT2,EMSY,PLSCR4" Drug 6168_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "APBB2,LGR5,PDE8B,ATP2B2,NRP2,SCAPER,THSD7A,CRLF1,SULT4A1,CRY2,DAPK3,SPOCK2,HS3ST2,TNK2,MRNIP,VPS13B,STX2,EYA1,FHL1,HPCAL4,FERMT2,GPD1,CACFD1,SYNPO,KCNN1,NRCAM,PFKFB2,RETREG1,ACSS3,SH3BGR,SH3BP2,CNKSR2,SP4,LHPP,RPGRIP1L,ICAM5,RUNDC3B,TUBB1,UBE3A,OSBP2,VGF,SLC17A7,KCNAB1,HRASLS" Drug 5426_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASIC1,C1QTNF3,BIN1,APLP1,APOC1,SGCE,BAIAP3,LDLRAD4,CACNA1A,SYNGR3,STOML1,CRMP1,VCAN,PPP1R16B,SEC14L5,DUSP9,ING4,MTSS1L,ZNF391,ACSL4,DLC1,DCTN2,SEPT9,SRCAP,GFER,POLL,MAPT,MGAT3,PDE1C,PURG,PRKCB,MAPK10,ZHX3,ATP10B,ARC,TACR1,TBCEL,TIMP4,TK2,XRCC4,DNALI1,ITM2C,PLSCR4,FAM13C" Drug 3842_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SEMA6A,ALK,BEGAIN,CDC42BPA,KCNAB2,APOC1,SEMA4G,ATP2B2,ST3GAL5,SCAPER,MYRF,CACNA2D1,CAMK2A,CDO1,ARHGEF6,CPS1,RUSC2,EGFR,TNK2,SPEG,AGAP2,TDRKH,KCNQ3,KIF5A,MAP4,MEF2C,MID1,NNAT,PCBP3,GPR85,STRN3,VPS13C,MRAS,OGDHL,RBM34,ZNF423,ARC,WSCD1,ZEB1,SZT2,TNS2,PCDHA6,SPHK2,SLC30A3" Drug 5053_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,SEMA6A,ALK,AMT,PPFIA4,CDK10,ADAM23,NRP2,BMP7,CAPN3,MAGI1,CACNA2D2,TAOK2,WHRN,EDN1,IGSF6,FGFR1,ERGIC3,SIGLEC8,RUNDC3A,KCNB1,KIT,KITLG,MYT1,NOVA2,PDE4A,PDE4D,ABCB1,DCHS2,PTPRB,PTPRN2,RGS4,KCTD17,EMID1,SUPT20H,ARHGEF40,UNC5B,DDN,ATP10B,DOCK9,SLC44A1,TLR4,VGF,SLC17A7" Drug 4765_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADRA1D,LTBP4,ARHGDIG,GYG2,CFAP410,AP4M1,ARHGEF2,ARHGAP33,WHRN,SH2B1,RIMS2,DOCK4,DBN1,EDNRA,DLC1,PDLIM5,GCNT2,STON1,PCLO,MEF2C,MYT1,NF1,NNAT,PDE4A,GRAMD1C,KCTD17,ZFHX4,RPS6KA2,PEX26,SLC9A5,ZHX3,ZNF423,ARHGAP26,SPTAN1,CLSTN2,CEP68,RGL1,PHLDB1,DMXL2,DOCK9,ZKSCAN5,HIRA,EMSY,TIGD6" Drug 5407_DN Ascorbic acid [50-81-7]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AP2A2,BCAS1,ARHGDIG,STX16,KIF1A,BMP7,SYNJ1,HAP1,SOCS6,SLIT2,PLAA,HOMER3,CREM,SH2B1,SIPA1L1,TOM1,MBNL2,HSD17B14,EZH1,F8,ACSL4,ATP2C1,GRIK5,CACFD1,ATXN2L,ELOVL5,HNMT,INPP5B,MIA2,KITLG,NFYA,RETREG1,PLXNB1,LRP12,ZDHHC14,ZNF821,SH3BP2,RBM34,LHPP,NXT2,PLCB1,AP4E1,EMSY,GDPD5" Drug 2237_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,AMPD3,APBA2,PLA2G4C,CFLAR,BMP7,HAP1,ARHGEF2,ARHGAP33,RCBTB2,AKAP7,SEC14L5,EIF4G2,ING4,COQ7,ANKMY1,ZNF589,BAIAP2,FHL1,FAM49B,TMEM8B,SRCAP,MALT1,COPS8,GNG4,ICA1,IPO5,MBD1,MIA2,MMP16,NEK1,PPP5C,TCP11L1,PREX2,PEX26,DOK5,SPTAN1,IQSEC2,STX1A,NSD1,TRIO,HIRA,SPHK2,SMIM8" Drug 6602_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SEMA6A,AMH,GAS7,APOC1,ATP6V0A1,GYG2,CACNB4,CAST,CRMP1,MFAP3L,EDN1,PLXNC1,CALCRL,F5,DCTN2,NSG1,GATM,PADI2,HLF,PACRG,MGAT3,NEFM,NF1,NOVA1,PDE4B,MTRF1L,POLG,PTPRB,RGS12,FBXW7,EMID1,MRAS,FRMPD1,PPP4R3A,LHPP,PLCB1,SYT5,MCF2L,PCDHA5,THRA,TIMP4,TLR4,KCNK12,KCNAB1" Drug 2862_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,BRAP,ATP6V0A1,CFLAR,CAMK2G,KRIT1,CBFA2T2,SCARB1,RCBTB2,HOMER3,NECTIN3,CSNK1E,PDE4DIP,GREB1,EDNRA,CELSR3,MBNL2,FGFR1,FAM49B,DISC1,SRCAP,POLL,HNMT,INPP5B,KHK,MAP4,PPP5C,PRKAB2,FAM184A,RGS3,CARF,CLIP1,TRAPPC13,SH3BP2,SYBU,GLT8D1,ELOVL4,TNS2,CRTC1,AP4E1,TK2,UBE3A,PLPPR2,LMF1" Drug 4648_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,SPARCL1,SYT13,KIF1A,ADAM23,ADGRB2,BMPR1B,KALRN,RUNX1T1,SLC16A4,CBARP,PCYT1B,CABP1,CRYBB1,CSF1,DTNA,EDN3,CELSR3,RASGRP2,MTSS1L,ARMCX1,FGF1,OLFM1,SIGLEC8,CSDC2,TOX3,SPACA9,HLF,ICA1,LAMA2,LSAMP,ADAM11,MGAT3,P2RX7,PPP1R1A,PRPH,PTPRB,ST6GAL1,SNAP25,FAIM2,SYNE1,TRO,LAMP5,SEMA3B" Drug 6767_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,AGT,NME5,C1QTNF1,AMT,CDC14B,CFLAR,BAIAP3,CFAP410,ARHGEF1,STOML1,AKAP7,SNPH,DGKG,MBNL2,VPS13B,OLFM1,FGF13,FHL1,GPD1,LPAR4,GRB10,GUCY1B1,TJAP1,JAK2,KCNJ5,MID1,AFDN,MMP16,MPP2,TAGLN3,ZNF862,NF1,CLDN11,PDE4A,NECAB2,MINDY2,ASAP3,TSPYL2,SYN2,AMACR,LAT2,KCNK12,SEMA3B" Drug 5068_UP Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASIC1,NDRG2,ALK,NRP2,CFLAR,CACNA1I,RUNX1T1,ENTPD2,ARHGEF10,DUSP9,COQ7,MTSS1L,SPEG,FGFR1,FYB1,PCDH17,ATXN2L,KCNJ5,KIT,LIFR,LSS,MATN3,LYRM9,NPR2,NTRK2,PRKAR1B,GRAMD1C,PTPRN2,FBXW7,EMID1,NCBP3,SLA,SLC12A4,SNCA,ZHX3,SPTB,ZBTB43,DDN,PHLDB1,COBL,KIAA1107,TCF4,SLC44A1,KCNAB1" Drug 5856_UP Milrinone [78415-72-2]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "RALGAPA1,ARRB2,NRXN3,CLTB,QKI,CNTFR,CNTN1,DZIP3,TBC1D5,LYPD1,PARD6A,ECM2,EDIL3,FAM13A,EGFR,RASGRP2,ETV1,OGA,FYB1,ERAP1,GCNT2,SRCAP,LILRA2,PADI2,INPP5B,MAPT,CNOT4,PRODH,BCAS3,MARCH1,SCN8A,SLA,KDM4D,FAIM2,ATP10B,COBL,TAL1,PCDHGB6,OBSL1,R3HDM1,CHST5,NT5M,UBE3B,DPF3" Drug 4666_UP Probucol [23288-49-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADRA1D,LTBP4,CDK10,SEMA4G,ATP2B2,ADGRB2,SYNJ2,IL33,CACNA1A,CALB2,ARHGAP33,SOCS6,COL9A3,DPH1,ZNF391,PIPOX,EZH1,ABCA8,PRELID3A,GLYR1,STON1,ATXN2L,HLF,ICA1,KCNF1,KCNJ5,KIFC3,LMO2,NF1,NPTX1,P2RX7,KCTD17,MRAS,KANSL3,SLC12A4,LIMCH1,KDM4B,TROVE2,PHLDB1,PLCB1,ZNF34,TNS1,VGF,KCNAB1" Drug 1489_UP Antipyrine [60-80-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "BIN1,AMT,CDC42BPA,APC,BCAS1,MARK4,ATP2A2,BACH1,MPDZ,CFLAR,SYNJ2,B4GALT6,QKI,SULT4A1,CREM,FAM169A,DZIP3,ZNF804A,LYPD1,DMPK,EDNRA,LRRC17,DLC1,FER,FHL1,TPK1,INPP1,IPO5,MBD1,PDE4A,RETREG1,C1orf54,EMID1,SH3BGR,SH3BP2,ASAP3,SLC2A5,MAPKBP1,RBM34,KDM4C,CRTC1,CHST8,R3HDM1,REEP1" Drug 4311_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "LTBP4,ANK2,GAS7,BMP7,BMPR1B,SYNJ2,LDLRAD4,RUNX1T1,LHX2,AKAP5,NCOR2,DMPK,TENM1,ELN,OLFM1,FGF12,FGFR3,FOXF2,AFF2,DCTN2,SEPT9,GPR162,CSDC2,RAB30,PRUNE2,ITGA7,NPTX1,NPTX2,NRCAM,PCDH9,CDK18,PFKFB4,PPP2R2B,LRRN3,PRKAR1B,RET,PNMA8A,SCN2B,HECW1,KLHL4,XRCC4,ZNF24,LAMP5,HRASLS" Drug 2329_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADD2,NME5,BEGAIN,BIN1,APC,PPFIA3,SEMA4G,CDK13,NUMB,ADAM23,GYG2,CACNA1A,CACNA2D1,FOXN3,TAOK2,AKAP7,GPRASP1,RASSF2,EDNRA,ELN,NRN1,AGAP2,POLL,GNAL,GRM8,TJAP1,KCNJ5,ADAM22,NNAT,NPTX1,NTRK2,PLCD1,PRKCB,C1orf54,ZDHHC14,KLHDC8A,SLC11A1,SP4,SPART,LMO3,ARC,WSCD1,RIMBP2,TRPM2" Drug 6751_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,PKP4,DDO,SEMA4G,CACNA1G,USP2,SYNGR3,CACNA2D2,ABCG2,AKAP5,SEC14L5,SPOCK2,DUSP9,EDN3,EDNRB,PLXNC1,TENM1,DCTN2,SIGLEC8,GNAL,TDRKH,ATXN2L,ELOVL5,IL6ST,ITGA7,LAMA2,MX1,NNAT,NTRK3,CLDN11,P2RY1,PALM,GPR85,PPP1R1A,BEND5,ZNF821,SLC11A1,ATP10B,PHLDB1,TRO,HIRA,EPM2A,KAT6A,DPF3" Drug 6489_DN Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AMH,APC,EPB41L5,CFLAR,C5,CA12,MAGI1,DBN1,DBT,EGFR,BAIAP2,SEMA4D,PDLIM5,INPP5K,SRCAP,AHDC1,GNG4,SPACA9,KCNH2,MAP4,GIT1,ZNF862,NF1,POLG,CNNM2,RIPOR1,EMID1,SAFB,ZNF821,SH3BP2,ABLIM3,SLC22A4,ZHX3,UNC5B,TACC1,EXOC7,CDK20,SSBP2,VLDLR,KLC2,KCNK12,XRCC4,MAP3K12,ST7" Drug 2578_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "PKP4,APAF1,CDK13,MYRF,CACNB4,SLC16A4,CDH2,VAX2,NRG2,CRY2,SLITRK5,USP6NL,DBT,KIAA0753,TMCC2,E2F5,F5,GALC,ERAP1,ALDH1L1,GPR162,GSN,PADI2,TJAP1,LSS,MGAT3,NFYA,CLDN11,PDE4D,POLG,LRRN3,BCAS3,ZFHX4,EMID1,RXRA,ASAP3,FAM214B,PKNOX2,FAIM2,TMCC1,ARHGEF9,DNMBP,THRA,ZBTB38" Drug 4211_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,AGT,TRMT9B,APOC1,ARHGDIG,KALRN,ARHGAP22,LHX2,LY86,PICK1,IQCK,CSF1,RGS6,DZIP3,RIMS2,SEC14L5,DTNA,DUSP9,PLXNC1,EPB41,MTSS1L,F5,ST3GAL6,FGFR1,GRM8,PACRG,NF1,NTRK3,PDE4D,PIK3R1,PLXNB1,PTPRB,ZCWPW1,MRAS,KANSL3,ASTN2,GPR161,TIMP4,UGT8,VGF,XRCC4,NDRG4,SPHK2,KCNAB1" Drug 1305_DN Carcinine [56897-53-1]; Down 200; 22uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "C1QTNF3,MARK4,NCOA1,N4BP2L1,ATP6V0A1,SCAPER,CAPN3,TPP1,IQCK,ARMC8,PREPL,CTH,ZNF337,MATR3,ZNF804A,B3GAT3,DTNA,ERCC2,ANKMY1,TRMO,CINP,IL6R,INPP5B,SLC11A2,MAPK3,RAD51D,CCDC25,SAFB,HSPA4L,SH3BP2,AMBRA1,DZIP1,PEX26,ARFGAP1,NXT2,PJA1,FBXW11,SYNE1,NSD1,TPM1,SSBP2,UBE2H,MPPE1,SMIM8" Drug 1313_UP Carbarsone [121-59-5]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ABHD6,MTUS1,ARNTL,NUMB,MYRF,CAPN3,KRIT1,CCNT1,SCARB1,CLGN,EPS15L1,BAG4,CREM,CSNK1E,PDE4DIP,SLITRK5,PPP1R16B,SPATA2,RUSC2,SGSM2,DTNA,PHC2,SUGP2,PTK2B,CELF1,SEPT9,ADAM28,RAB40B,POU6F1,RELN,ZNF493,TRIM68,RNASEL,EXD2,SLC2A5,BTBD7,TMCC1,DOK5,SPTAN1,TROVE2,EXOC7,ZEB1,PARD3,TRIM9" Drug 7020_DN Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG3,EP400,CDK10,C5,CCNT1,CLCN3,C2CD2,NCOR1,SIPA1L1,DCAF8,KIAA0586,GIT2,SGSM2,DTNA,MAMLD1,OPTN,SUGP2,VPS26C,FGFR1,PDLIM5,ATP2C1,SYT17,RNFT2,HNMT,DHX35,MAP4,SMOX,SLC25A23,STRN3,TRAPPC13,ZFP30,AMBRA1,SYBU,IFT122,MAPKBP1,LHPP,MTCL1,MCF2L,TRIM2,TSC2,UBTF,LMF1,SPHK2,FIP1L1" Drug 4352_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,SEMA6A,ALK,PKP4,CFLAR,C5,ARHGAP33,CSF1,DZIP3,DTNA,HIPK3,ING4,STX2,PTK2B,SCARA3,SRCAP,PCDH17,RAB30,STON1,GPR37,GRIK5,KITLG,MMP16,LYRM9,NF1,LRP12,MAPK7,ZSCAN32,NEK11,TCP11L1,RASA3,ASAP3,PPP4R3A,CXXC4,SMARCD3,PDZRN3,DOP1A,CLASP2,NXT2,TTBK2,PHLDB1,VPS13A,WSCD1,BEX4" Drug 4435_UP retinoic acid; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADRA1D,AGT,BEGAIN,GAS7,CDC14B,PDE8B,ASPA,N4BP2L1,KIF1A,GYG2,KALRN,CAMK2B,CDO1,PICK1,CSF1R,C2CD2L,SPOCK3,CHRDL1,SRPK3,ZNF391,APC2,REEP2,DCTN2,GATM,SRCAP,GLI2,NPY,GPR85,PURG,PPP5C,PTCH1,PTPRN,PTPRN2,RGS12,NEK11,SH3BP2,FAM214B,RBM34,KLHL4,CHST5,TRIO,SLC17A7,KAT6A,GAN" Drug 3872_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADORA1,AMH,AMPD3,APBA2,CHRD,CACNA1I,LDLRAD4,CACNA1A,CAMK2B,TAOK2,WHRN,NCOR1,GREB1,SEC14L5,RUSC2,TMCC2,EDNRA,DLC1,GDF9,GFER,GRIK5,HLF,TJAP1,KCNN1,MIA2,CNOT4,PCBP3,PFKFB2,LRP12,PTN,RGS12,RPS6KA2,SATB1,SLC2A5,SLC11A1,SSTR1,ARC,TBCEL,OBSL1,TNS1,HIRA,LAT2,SLC30A4,SLC17A7" Drug 3904_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AMPD3,APAF1,APC,APOC1,PRX,PDE8B,KSR1,CACNA1I,CFAP410,NRXN3,ARHGEF6,FAM149A,CRYM,KIAA0586,SPOCK2,RUSC2,EDNRB,C3orf18,SPEG,CAMKK2,GPR162,GLYR1,POLL,TDRKH,GRIK5,KCNJ5,MATN3,AFDN,NNAT,NOVA2,LRP12,MINDY2,PRKCB,RPS6KA2,ZNF821,PKNOX2,ARHGEF40,CXXC4,SNAP25,SOX15,THSD1,PHLDB1,DMXL2,SPHK2" Drug 4062_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "BEGAIN,CDK13,ATP2B2,BCHE,RGS9,BMP7,CBARP,NRXN3,STOML1,AKAP6,RCHY1,NRG2,NCOR2,CSF1R,CNTNAP2,C2CD2L,DMD,EDIL3,EDNRA,ZNF391,PTK2B,DLC1,AGAP2,DISC1,CYP46A1,PCDH17,POLL,IRAK3,ELOVL5,IGF1,KCNF1,AFDN,NINJ2,PDE4D,PFKFB2,RGS4,SEMA6D,SCN2B,PKNOX2,SS18,KLHL4,DICER1,KCNK12,KCNAB1" Drug 2803_DN Yohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SRPX,AMPD3,CDC42BPA,GAS7,APOC1,SEMA4G,PPP4R4,ARHGDIG,ATP6V0A1,CFLAR,MTMR3,GYG2,CRLF1,FOXN3,SULT4A1,AKAP5,CSF1,SPOCK2,JAKMIP2,MFAP3L,LYPD1,FGFR1,FHL1,B4GALNT1,SRCAP,MSL3,INPP1,KHK,LMO2,SMAD1,MAP4,MX1,NPTX1,NLE1,PRPH,GTDC1,TCP11L1,SMARCA4,LIMCH1,ZHX3,PARD3,ZFP37,KCNAB1,EPM2A" Drug 7172_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "APOC1,CDK10,CFLAR,SYNJ2,SCAPER,GYG2,CAMK2B,SCARB1,QKI,SLC4A8,BAG4,DBN1,PARD6A,RCAN1,OPTN,MBNL2,DENND4A,DLC1,EFCAB2,POLL,GRB10,CACFD1,LMO2,MEIS2,MPP2,NNAT,PDE4A,SNRK,ELOVL2,RGS12,TCP11L1,FUZ,PPP4R3A,ZKSCAN3,PHLDB1,VPS13A,SYT5,PCDHGA10,THRA,TPM1,NPL,TRIO,FLRT2,MPPE1" Drug 6006_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "FAM131A,APOC1,CDK13,EIF4G3,GYG2,KRIT1,QKI,HOMER3,CREM,EPB41L2,ZNF589,FGFR3,SEMA4D,TXNL4A,RAB30,RAB40B,TDRKH,GRB10,MAP4K5,INPP5B,ITPKB,LIG4,MAP4,MITF,SETD4,PMP22,PRPH,TMEM104,RNASEL,SGK1,ZFP30,SH3BP2,FAM214B,MAPKBP1,ZHX3,IQSEC2,TTBK2,PLCB1,ASTN2,TRIM2,ZKSCAN5,ZFP37,REEP1,GDPD5" Drug 2243_DN Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,MARK4,BMP7,SYNJ2,GYG2,ARHGEF2,SLIT2,PICK1,RIMS2,CDON,EIF4G2,EIF5,DISC1,GNG4,GRIK5,TJAP1,LSS,MAP4,ADAM22,NF1,NPR2,CDK18,MBOAT7,PRKAR1B,PRPH,CEP97,C1orf54,ZDHHC14,RGS12,EMID1,SMARCD3,TSNAXIP1,IQSEC2,CLSTN2,PHLDB1,STX1A,PLCB1,NSD1,AP4E1,VGF,ZNF24,SPHK2,KCNAB1,TIGD6" Drug 6731_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NME5,C1QTNF3,MADD,CDK13,CFAP410,CACNA2D1,SCARB1,CACNA2D2,ASIC3,CHN2,TAOK2,QKI,AKAP5,LRIG1,VCAN,CNTNAP2,RIMS2,TBC1D5,DAPK3,MFAP3L,DMPK,HIPK3,DLC1,CAMKK2,OGA,GNG4,PRRC2B,ELOVL5,SHISAL1,IL12A,ADAM11,ADAM22,MX1,CNOT4,CCDC40,RGS12,FAIM2,HECW1,ZNF423,TROVE2,TK2,TNS1,VLDLR,PARP11" Drug 4778_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AP2A2,AMPD3,PPP4R4,CA12,CACNA1A,MTMR7,STOML1,AKAP7,CABP1,DYNC1I1,LYVE1,GLI2,GRIK5,KCNJ5,KCNN2,MPP2,NTRK2,DUSP26,PURG,PPP1R1A,PRKAR1B,PTN,C1orf54,EMID1,FNDC3A,PREX2,SLC2A5,PPP4R3A,CXXC4,SMARCD3,FAIM2,ZC3H13,TROVE2,NXT2,ADGRL3,TBCEL,IQCE,WSCD1,TRIM2,PCDHA5,SLC35G2,VIPR2,ZFP37,MKRN3" Drug 3169_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "KDM5D,BEGAIN,AMT,APAF1,KCNAB2,ARHGDIG,ATP1A3,GYG2,CAMK2B,HIP1R,ARHGAP33,FOXN3,CHN2,B4GALT6,TPP1,STOML1,CPS1,OSBPL3,DOCK4,TMCC2,DTNA,PLXNC1,TNK2,ERBB4,OLFM1,FYN,SEPT9,TDRKH,ICA1,JAK2,NOVA2,CDK18,ENPP2,MAPK10,RASGRF1,CCDC88A,SP4,IZUMO4,EXOC7,SZT2,TEK,UGT8,XRCC4,ZNF45" Drug 7075_UP AH6809; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ABHD6,NME5,C1QTNF1,AMPD3,BIN1,APBA2,APBB2,APC,PPFIA3,SOCS6,CHN2,CLCN3,QKI,BAG4,CPS1,CREM,ABCG1,USP6NL,EDNRA,GCNT2,GLI2,POLL,FERMT2,MAP4,MX1,NDP,CEP41,TMEM104,PEX26,CCDC88A,COA1,IFT122,KIF13A,KDM4B,PLCB1,TCF4,KIAA0930,CABIN1,METTL3,NPDC1,NDRG4,UPF3A,URM1,PHTF2" Drug 4115_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SYN3,ALCAM,LTBP4,ALK,SYT13,SYNJ1,SYNJ2,CACNA1G,CBFA2T2,CRLF1,SLIT2,WHRN,VCAN,DAPK1,MRNIP,ZNF391,SPEG,DCTN2,SIGLEC8,ICA1,KCNN1,MMP17,ADAM22,MX1,MYO7A,PDE4D,GPR85,RETREG1,PPP5C,PRKAR1B,PRKCB,CNTLN,CCDC40,RNASE1,RNASEL,ARHGEF40,SLC11A1,ARHGAP26,EXOC7,SZT2,RUNDC3B,UGT8,MKRN3,SLC17A7" Drug 4076_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "BEGAIN,ZSCAN18,BMP7,FUBP1,IL33,CACNA2D1,CAMK2B,SCARB1,AKAP6,CRY2,CSF1,CSF1R,SPOCK3,EDIL3,HPCAL4,AGAP2,PDLIM5,PRELID3A,GNAL,NXPH3,ITPKA,KHK,LSS,ADAM22,NPTX2,NRCAM,NTRK2,PDE4B,ENPP2,PLCD1,NECAB2,PTCH1,PTPRB,GAL3ST4,RFX2,RGS12,RNASEL,ZNF334,SNAP25,ZHX3,ARC,GPR161,ZNF24,SLC17A7" Drug 7414_UP Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,APAF1,BCAS1,ST3GAL5,CRMP1,CRY2,ARHGEF10,FAM169A,ARHGEF4,SNX29,EGR3,COQ7,BAIAP2,SCARA3,B4GALNT1,SEPT9,POLL,SPACA9,GRIK5,DHX35,JAK2,KITLG,NF1,SETD4,PTPRE,RIPOR1,KCTD17,GSTCD,MAPK12,SYBU,PKNOX2,SMARCD3,MAPKBP1,KDM4B,TTBK2,RGL1,PHLDB1,ARHGEF9,PLCB1,ANKRD12,ZNF34,ZNF24,ZNF45,NDRG4" Drug 6876_UP BAS 012416453; Up 200; 38uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "RALGAPA1,MTUS1,AMT,APAF1,APC,EPB41L5,GAS7,ARHGDIG,KALRN,CBS,CNTFR,ARHGEF4,PYGO1,CYBB,DAPK3,DBT,PLPPR4,SPOCK3,HIPK3,ZNF549,ETV1,OLFM1,DISC1,GCNT2,GLYR1,ICA1,IGF1,MSR1,NELL2,NF1,PIK3R1,FSD1,MINDY2,SAMD9,SCN8A,PEX26,ELMO2,SNCA,SS18,CEP68,PHLDB1,CUX2,UGT8,ZFP37" Drug 7071_DN CAY10397; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ABR,PPFIA3,SEMA4G,ADAM15,CFLAR,SYNJ2,ARHGEF7,MYRF,AP4M1,PLAA,RAB26,CSF1,VCAN,ZNF337,TBC1D5,FCF1,BAIAP2,ANKFY1,PDLIM5,INPP5K,SRCAP,USP19,AGBL5,SHISAL1,NFYA,PDE1C,CCSER2,PLEC,MAPK7,GRAMD1C,MCMBP,ANKRD6,COA1,SMARCA4,RCOR3,THSD1,NXT2,VPS13A,SYT1,FRYL,LMF1,ZNF32,ZBTB38,PCBP4" Drug 7355_UP Harpagoside [19210-12-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "C1QTNF3,BEGAIN,AMPD3,APAF1,APBA2,ATP6V0A1,MPDZ,SYNJ2,SCAPER,BAIAP3,CA4,SRSF11,B4GALT6,HOMER3,FAM169A,GREB1,ARHGEF4,ING4,DENND4A,EZH1,OGA,GNG4,SPACA9,CACFD1,ELOVL5,HNMT,KCNH2,MEIS2,MMP16,GTDC1,ZNF821,FAM214B,SLC22A4,SMARCC2,LIMCH1,RBM34,KDM4C,PHLDB1,ARHGEF9,PLCB1,WSCD1,BEX4,HPS4,ACTR3B" Drug 5358_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "AP2A2,AK2,PPP4R4,DNAH17,MARK4,ATP6V0A1,CFLAR,KSR1,SYNJ2,SCARB1,SLIT2,CSF1,MAML1,SPOCK2,DNM1,SEZ6L2,NCALD,CDKL3,DLC1,KAT8,ZNF589,BAIAP2,INPP5K,SLC2A6,ELOVL5,MAP4,PPP2R2B,ZFHX4,FBXW7,SH3BP2,PEX26,UNC5B,SS18,TBL1X,CRTC1,SLC44A1,FAM155A,KCNK12,XRCC4,NDRG4,TFIP11,EVI5,GDPD5,UBE3B" Drug 3079_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,LDLRAD4,SOCS6,PLAA,CPS1,SEC31B,PDE4DIP,TM9SF4,DTNA,MBNL2,TUBD1,COQ7,PIPOX,FECH,IQCG,FLT1,TRMO,ERAP1,GPD2,GSN,FICD,ACOT7,KPNA5,LAMA2,AFDN,ZNF862,NFYA,NRCAM,PDE4A,PEX26,FAM214B,SLC6A8,CDK19,ZC4H2,SS18,KANK1,DMXL2,AP4E1,HIRA,FLRT2,PLPPR2,XRCC4,EMSY,KCNAB1" Drug 3097_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SYN3,ANK2,FGD2,SEMA4G,PLA2G4C,DNAH17,KSR1,THSD7A,CD38,CHN2,TAOK2,STOML1,RAB26,FAM149A,CREM,AATK,RIMS2,SEZ6L2,TNK2,C3orf18,FHL1,GPR75,KCNJ5,MGAT3,AFDN,MPP2,MX1,LYRM9,TREM2,PFKFB4,NLE1,RGS3,ZNF821,CCDC92,SLC11A1,RBM34,ARHGAP26,EXOC7,DOCK9,THRA,TNS1,SPHK2,MAP3K12,NT5M" Drug 4423_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASIC1,ADORA1,ADRA1B,APC,DNAH17,CFAP410,CALB2,HIP1R,LDB2,TPP1,OSBPL3,CNTNAP2,PHF14,DGKG,ELN,RASGRP2,DLC1,OLFM1,ERAP1,RUNDC3A,GPER1,GRIK5,SYNPO,INSM1,LAMA2,MAPT,MX1,P2RX7,PFKFB2,PPARA,PID1,GAL3ST4,TRIM68,MRAS,ST6GAL1,ARHGEF40,OGDHL,PEG10,ARHGAP26,TAL1,DOCK9,WIPF1,MKRN3,DPF3" Drug 4006_DN Oxamniquine [21738-42-1]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "APBB2,LGR5,ALDH7A1,ST3GAL5,RAB26,SH2B1,C2CD2L,CDON,DTNA,MBNL2,IRAK4,MRNIP,COQ7,MTSS1L,ANKMY1,ST3GAL6,ZNF44,GAD1,GFER,TDRKH,LPAR4,SHISAL1,KPNA5,MN1,TAGLN3,ZNF862,NOVA1,MAPK7,GRAMD1C,PRPH,KIRREL1,SH3BP2,PEX26,TSNAXIP1,THSD1,ARC,KIAA1107,TMEM121,TK2,WIPF1,REEP1,NT5M,KCNAB1,TIGD6" Drug 5201_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,SRPX,BIN1,APBB2,APC,LDLRAD4,CBFA2T2,ARHGAP33,CHN2,WHRN,GREB1,SPOCK2,RUSC2,SLC12A6,DUSP9,EDNRA,FAM198B,DLC1,OLFM1,FGF12,SRCAP,RUNDC3A,GRIK5,IRF8,KCNN1,MID1,MPP2,ZNF862,NEFM,NF1,PPP5C,TMEM231,C1orf54,ZNF493,GSTCD,RPS6KA2,DOK5,PLCB1,ZEB1,TRIM2,RUNDC3B,SLC30A3,NT5M,TIGD6" Drug 4389_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASIC1,DDO,AZGP1,BACH1,KSR1,GYG2,CNOT8,CLTB,ARHGEF10,VCAN,SPOCK2,CDON,EDN3,FAM13A,MBNL2,TNK2,ELN,CORO2B,DLC1,OLFM1,FGFR1,AGAP2,SEMA4D,GABRG2,GAD1,GCNT2,MGAT3,AFDN,MX1,NPY,PALM,PDPK1,PLXNB1,RORB,KIF13A,SPP1,PLCB1,SYT5,TNS1,UGT8,OSBP2,WIPF1,LAT2,NT5M" Drug 2618_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "MTUS1,CDC42BPA,PPFIA3,NUMB,KIF1A,BCL7A,CFLAR,BMP7,CBR1,PLEKHB1,CLCN3,MAP4K4,CREM,DBT,FBXL5,SUGP2,PRRC2B,GPD2,MUM1,DHX35,HSF2,JAK2,KCNH2,KHK,MAPT,MPP2,GIT1,NF1,SETD4,PTCH1,GTDC1,CCDC25,ZNF821,AMBRA1,ZSWIM8,TSPYL2,TROVE2,NXT2,NEK4,TBL1X,UBTF,LMF1,ZNF74,MPPE1" Drug 7013_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADCY6,APBB2,GAS7,CDK10,PDE8B,MARK4,ALDH7A1,ARHGEF1,SCARB1,QKI,PDE4DIP,ARMCX2,DMPK,DTNA,PHF20L1,RACK1,TPK1,SEPT9,GRB10,MUM1,IL6ST,KCNH2,MAP4,MBD1,NF1,NFYA,SMOX,CNNM2,WDR25,PTCH1,SBF1,SH3BP2,PPM1E,LIMCH1,LHPP,ANKRD12,KIAA1107,TRIM2,PARD3,ZKSCAN5,PLPPR2,VAV1,VLDLR,SEMA3B" Drug 5688_UP Altretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ADGRF5,SPARCL1,SYT13,CDC42BPA,APAF1,PRX,LDLRAD4,SEPT7,CHRNA4,SLIT2,WHRN,VCAN,ARHGAP24,CDON,SLC12A6,EDN3,EGFR,MRNIP,RASGRP2,FGFR3,FLT1,RAB30,SOX21,GUCY1B1,SYNPO,MEF2C,MGAT3,PDE4D,PFKFB2,MAGEL2,MASP1,PTH1R,RGS12,TCP11L1,ZNF821,MYH15,SAMSN1,PLCB1,PCDHGB6,DOCK9,CA14,WIPF1,EPM2A,HRASLS" Drug 6309_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "PDE8B,KIF1A,SCAPER,SCARB1,NRXN3,QKI,CNTFR,CRMP1,ARMCX2,KIAA0753,DMPK,EDIL3,TENM1,COQ7,ETV1,RRAGB,ZNF589,PRELID3A,SPACA9,GRIK5,HSF2,KHK,KIFC3,NF1,CNOT4,NOVA2,OPRL1,PLCD1,SAMD9,PTCH1,PTPRB,PTPRH,ENOX1,SUGCT,CCDC88A,KDM4B,DDN,PHLDB1,ARHGEF9,KIAA1107,CRTC1,PIK3R5,NDRG4,NT5M" Drug 4071_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASPHD1,ADRA1D,AMH,AMPD3,APOC1,PPP4R4,ATP1A3,ADAM23,CFAP410,AKAP7,ARMC8,AKAP5,NCOR2,CSF1,CNTNAP2,ARHGEF4,RIMS2,PLPPR4,DTNA,FGF1,SEMA4D,ZNF44,SEPT9,SRCAP,LPAR4,MEF2C,MGAT3,MPP2,ADAM22,NNAT,CLDN11,P2RY1,SERPINI1,WDR25,ZSCAN32,DZIP1,KANSL3,ASTN2,MCF2L,TK2,OSBP2,WIPF1,ZNF32,SLC17A7" Drug 4255_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "SPARCL1,BEGAIN,PKP4,ZSCAN18,BACH1,ADGRB3,SYNJ2,MTMR3,THSD7A,USP2,VAX2,FAM149A,CSF1,CNTNAP2,DMPK,DTNA,EDN3,EDNRA,TENM1,EPHB1,ZNF391,PTK2B,CORO2B,FGF12,AFF2,DENND2A,ERAP1,NEU3,PCDH17,GRIK5,MMP16,NNAT,GAL3ST4,NEK11,PREX2,PKNOX2,CXXC4,SNCA,TROVE2,TBL1X,ZNF34,TPM2,UBE3A,KAT6A" Drug 4204_UP Epitiostanol [2363-58-8]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "NDRG2,AP2A2,DOC2A,KCNAB2,APC,EPB41L5,GAS7,RASL11B,SCARB1,LARGE1,SULT4A1,AKAP5,HAPLN1,PHF14,DBT,HIPK3,ETV1,FLT1,AFF2,PDLIM5,ERAP1,GATM,MSTN,LYVE1,TXNL4A,TDRKH,STON1,CNTRL,MX1,MYO7A,NF1,NTRK2,ACSS3,SUSD4,SEMA6D,ZFP30,ST6GAL1,PREX2,SLC14A1,SMARCD3,MCF2L,PCDHA5,TPM1,SLC17A7" Drug 5050_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "APAF1,CDK10,ST3GAL5,KALRN,HAP1,SCARB1,WHRN,CABP1,FAM131B,MFAP3L,EDIL3,HIPK3,COQ7,SPEG,PTK2B,HPCAL4,PRELID3A,SYT17,RUNDC3A,GLYR1,GPER1,GRIK5,LIFR,NPTX2,NTRK2,CLDN11,PFKFB2,PLCD1,PPARA,CEP41,PRKAR1B,CNNM2,PTPRB,FAT4,GAL3ST4,TCP11L1,ST6GAL1,ZHX3,SPTB,PHLDB1,SLC44A1,WIPF1,ZNF74,ZNF225" Drug 3839_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "ASIC1,NME5,SEMA7A,APLP1,RASL11B,SCAPER,PICK1,CNTN1,DBT,DTNA,EGFR,LRRC17,F5,FGF1,SCARA3,KHDRBS3,CPLX2,GCNT2,SRCAP,CSDC2,RUNDC3A,TDRKH,PCLO,C2orf72,KCNH2,KCNJ5,KCNQ3,MAP4,TM6SF1,MSR1,FXYD7,NNAT,MAPK7,ARHGEF40,FAIM2,KDM4B,IZUMO4,ZNF423,DMXL2,PIK3R5,SPHK2,EMSY,ADAMTS9,KAT6A" Drug 5470_UP Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "RALGAPA1,ASIC1,NDRG2,AP2A2,C1QTNF1,BIN1,SEMA7A,SEMA4G,PPP4R4,CFLAR,HAP1,CAMK2B,TAOK2,PICK1,WHRN,CSF1R,GPRASP1,C2CD2L,PDLIM5,ERAP1,SRCAP,RUNDC3A,GPD2,LILRA2,CNTRL,HNMT,IL6ST,KCNN2,KIF5A,MYO7A,KLHDC8A,NEK11,FRMPD1,CNKSR2,ATP10B,ST5,MCF2L,SZT2,CHST8,TK2,TRIO,VIPR2,SPHK2,GDPD5" Drug 4206_UP Pepstatin A [26305-03-3]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 4.48E-01 2.65E-04 2.98E-03 44 199 "GAS7,SPTBN4,NRP2,SYNJ1,SCARB1,CNOT8,CNTN1,CSF1,PDE4DIP,CNTNAP2,RIPOR2,DTNA,EDIL3,HIPK3,TNK2,ETV1,HPCAL4,PRELID3A,DENND2A,DISC1,GATM,KCNJ5,LAMA2,SMAD1,KITLG,ADAM22,LYRM9,NF1,PPARA,PTN,GAL3ST4,RGS3,NEK11,FBXO11,PREX2,OGDHL,SNCA,ZC3H13,MCF2L,PCDHA6,TK2,R3HDM1,FLRT2,KCNAB1" Drug 1301_UP Domperidone maleate; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "NDRG3,APBB2,STX16,ST3GAL5,SCARB1,CLGN,SRSF11,STOML1,QKI,AKAP7,ARMC8,CREM,CSNK1E,DZIP3,CTH,FCF1,FAM13A,COQ7,OGA,LIG4,MAP4,MEST,MPP2,N6AMT1,NEK1,PIK3R1,CCSER2,MINDY2,RIPOR1,RET,SBF1,FERMT1,FBXO11,ELMO2,THSD1,LARP4,SS18,NXT2,FBXW11,ZEB1,CRTC1,ZNF34,ZBTB38" Drug 4279_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "APBB2,CDC14B,CCNT1,SRSF11,CLCN3,ABI3BP,CSF1,NR1D2,EGFR,MBNL2,SEMA4D,PDLIM5,SPIN1,POLL,BACH2,AGFG1,IL6ST,JAK2,MMP16,LYRM9,NF1,CNOT4,SLC11A2,NTRK2,RETREG1,STRN3,ACSS3,SLC25A36,KIRREL1,ATXN7,SEC14L1,ASAP3,CCDC88A,KDM4B,SPTAN1,THSD1,ASTN2,TBL1X,DICER1,TRIO,USP1,KCNAB1,KAT6A" Drug 5218_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "ALK,AMT,APBB2,CFAP410,CA4,SLC16A4,CDO1,TAOK2,HOMER3,ARHGEF10,GREB1,MBNL2,ING4,CORO2B,FGF12,AGAP2,PCDH17,GLYR1,MSL3,GRIK5,GSTM5,ICA1,ITGA7,KCNN2,MAP4,ZNF862,NOVA2,PLCD1,PPP5C,WDR25,ZSCAN2,C1orf54,TCP11L1,FAM214B,HECW1,SPTAN1,ATP10B,STX1A,SYT5,KIAA1107,XRCC4,MARCH8,TIGD6" Drug 4650_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "NME5,FAM131A,APOC1,LDLRAD4,SPAG9,CNOT8,QKI,BAG4,ENTPD4,SLITRK5,EXOG,ING4,DENND4A,SCML2,ZNF589,ANKFY1,HNMT,SHISAL1,FAM69A,KIF2A,LIG4,NDP,CNOT4,NPR2,PLCD1,SNRK,PTK2,PTN,RGS4,CLIP1,TRAPPC13,ZNF821,ZFP30,FUZ,FNDC3A,LIMS2,SMARCD3,SS18,TCF4,TMEM121,BHLHB9,UBTF,WIPF1" Drug 3677_DN Salbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "ABR,ACTN1,ADRB2,CDC14B,SEMA4G,CDK13,NUMB,MYRF,HAP1,RCBTB2,SOCS6,PLEKHB1,NRXN3,HOMER3,CNTFR,CREM,APPL1,HDAC9,MFAP3L,PLPPR4,SGSM2,SPEG,FGF1,CGREF1,OGA,GNG4,TJAP1,INPP5B,KCNJ5,SMAD1,MBNL1,NF1,OCRL,GTDC1,CLIP1,ZNF667,KIF13A,ARHGAP26,PHLDB1,TCF4,TNS1,RUNDC3B,EVI5" Drug 4569_UP Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "C1QTNF3,LTBP4,PPP4R4,LARGE1,TAOK2,CRY2,VCAN,PDE4DIP,CNTNAP2,PHF14,PLPPR4,DTNA,PLXNC1,NCALD,PTK2B,CORO2B,FLT1,DENND2A,GAD1,ERAP1,TMEM8B,RUNDC3A,RAB30,KCNJ5,NEFM,PIK3R1,RETREG1,LRRN3,ELOVL2,CEP97,CCDC40,C1orf54,FBXO11,ST6GAL1,KIF13A,RBM34,TSNAXIP1,PCDHA5,AP4E1,TK2,ICAM5,OSBP2,FLRT2" Drug 3258_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.05E-05 4.60E-01 2.71E-04 3.05E-03 43 193 "MTUS1,AK2,OGT,EPB41L5,FAM131A,ARRB1,MPDZ,CFLAR,CACNA2D2,SOCS6,FAM169A,GREB1,TOM1,ING4,ERCC2,OGA,ZNF44,TXNL4A,FERMT2,IL6ST,ITPKB,KIF2A,NPTX1,PIK3R1,CCSER2,RGS12,SLC25A36,TRA2B,SLC22A4,MAPKBP1,KDM4C,DIP2A,PLCB1,MTCL1,TBL1X,KIAA0930,CRTC1,AP4E1,TIAM1,HIRA,VGF,XRCC4,ST7" Drug 1022_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.07E-05 4.70E-01 2.77E-04 3.12E-03 42 187 "AMT,KCNAB2,CDK13,ALDH7A1,ST3GAL5,SCAPER,CA4,CAMK2G,SCARB1,LETMD1,SLC4A8,ABCG1,LRIG1,DZIP3,SNX29,HIPK3,OPTN,ING4,MFSD10,ZNF589,SCARA3,B4GALNT1,SESN1,STON1,GPER1,CNTRL,ATXN2L,TJAP1,ADAM22,ZNF862,SLC25A23,MAPK7,CNNM2,FAM184A,ZNF821,LIMCH1,CDK19,ARHGEF9,DMXL2,ZNF34,TRIO,MARCH8" Drug 6193_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.09E-05 4.79E-01 2.82E-04 3.17E-03 41 181 "NME5,APBB2,HIP1R,CHN2,LHX2,RAB26,PDE4DIP,DZIP3,PARD6A,OPTN,MRNIP,ENO2,TBC1D16,FGFR1,BAIAP2,PCYOX1,RAB40B,STON1,PCLO,FAM69A,KHK,MYO6,PCDH9,SERPINI1,RETREG1,PTPN13,TMEM255A,RPS20,FAM102A,PPM1E,WDR47,ZSWIM8,SPTAN1,ELOVL4,RGL1,STXBP1,MTCL1,TRIM2,RPGRIP1L,HEY1,SLC17A7" Drug 3714_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "NME5,LTBP4,KCNAB2,PPP4R4,DNAH17,BMP7,CLDN10,USP2,CLTB,PDE4DIP,FRY,EPHB1,DLC1,SRCAP,GPD2,GSTM5,ITGA7,KCNN1,KCNQ3,KIFC3,ADAM22,NCAM2,NDP,NPTX2,NRCAM,OPRL1,PNMA3,PRKAR1B,ZCWPW1,RGS4,RORB,SALL1,SEMA6D,SLC12A4,ZNF334,KDM4C,LHPP,ARC,SLC44A1,TNS1,CDK20,VIPR2,WIPF1,MKRN3" Drug 2908_DN Nifurtimox [23256-30-6]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "APC,GAS7,ADAM23,ENTPD6,TAOK2,LHX2,CRY2,PDE4DIP,PPP6R2,GPRASP1,RUSC2,EXOG,ECM2,TOM1,PLXNC1,PTK2B,EVL,ZNF44,ERAP1,SRCAP,ADAM28,CRCP,PCLO,PADI2,MEF2C,OXTR,CCSER2,PLCL1,PMP22,PILRA,BEND5,RET,SEC14L1,ZNF821,RASA3,DBNDD2,STX1A,PDLIM2,OBSL1,PARD3,TPM1,MAP3K12,PRDM10,KCNAB1" Drug 3806_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "LTBP4,TRMT9B,CDK13,BMP7,CACNA1I,C5,BAIAP3,CA8,HIP1R,RUNX1T1,CDO1,SULT4A1,CNTN1,HAPLN1,CRY2,DMPK,DTNB,EZH1,BAIAP2,PDLIM5,STON1,TPPP,KCNN1,KHK,MGAT3,MYH3,NRCAM,NECAB2,PPP2R2B,PRKCB,CNTLN,CCDC40,ZMAT4,RNASE1,PNMA8A,SEMA6D,FAIM2,ATP10B,DOCK9,ICAM5,TPM1,XRCC4,ZNF225,NT5M" Drug 3825_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "APAF1,ARSE,MYOM1,LDLRAD4,CAMK2B,DLGAP2,CDO1,TAOK2,TPP1,RAB26,CABP1,AATK,CNTNAP2,C2CD2L,SV2B,DTNA,EPHB1,GABRG2,DISC1,ALDH1L1,SRCAP,LYVE1,GRM8,AP4S1,IRAK3,C2orf72,KCNN2,LSS,MIA2,MYT1,NPTX1,NRCAM,GPR85,PGAM2,FSD1,LRRN3,PTN,KLHL11,CNKSR2,FAIM2,SYN2,PCDHGB6,HIF3A,TUBB1" Drug 5737_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "APAF1,DDO,ARHGDIG,BMP7,ST3GAL5,HAP1,SCARB1,HOMER3,COL9A3,CSF1,CSNK1E,CNTNAP2,SPOCK2,SV2B,HS3ST2,COQ7,CORO2B,FGFR1,ERAP1,SRCAP,GNAL,GNAO1,HLF,KIF5A,MEF2C,AFF1,PDE4A,PIK3R1,PRKAR1B,MAPK7,ZCWPW1,RGS4,NEK11,SCN8A,SLA,SLC11A1,ZNF334,SPTAN1,LHPP,ATP10B,TCF4,AP4E1,ZNF34,LMF1" Drug 6150_UP Ramipril [87333-19-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADORA1,OGT,APBB2,APOC1,BMP7,BAIAP3,RUNX1T1,CBARP,ASIC3,SIPA1L1,SPOCK2,SV2B,SPOCK3,CELSR3,ING4,AGAP2,ALDH1L1,GNAL,SCIN,KCNB1,KCNN1,MBP,MPP2,NRCAM,NTRK2,PDE4A,FSD1,PPP2R2B,PNMA8A,FERMT1,ST6GAL1,PKNOX2,SLC11A1,FAIM2,IZUMO4,HECW1,DDN,ADGRL3,DMXL2,TEK,DNAH7,KCNE5,UGT8,SH3GLB2" Drug 4469_UP Stachydrine hydrochloride; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "AP2A2,AMPD3,GAS7,SLC2A11,RGS11,NRP2,CHN2,EPS15L1,RIMS2,C2CD2L,KIAA0319,EDNRA,ELN,REEP2,KAT8,FGF1,FGF12,SIGLEC8,GLI2,PRUNE2,TDRKH,ADAMTS13,IL6R,ITGA7,KCNN1,ADAM22,MSR1,PFKFB4,DCHS2,PTPRH,PTPRN2,RGS3,KCNIP1,SLC2A5,PKNOX2,SLC11A1,SOX15,ZHX3,SYT5,TNS1,VAV1,VIPR2,PRDM10,KCNAB1" Drug 3176_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "SYN3,ANK2,APLP1,ARHGDIG,ATP1A3,AZGP1,SLC16A4,DGKI,RAB33A,LY86,CNN3,CNR1,SLC4A8,CNTNAP2,HEPH,KLHL3,DUSP9,EDNRB,EPB41,ACSL4,AGAP2,FYN,SEPT9,SRCAP,CSDC2,LILRA2,HAS2,KPNA5,NOVA2,CLDN11,SCN2B,ZFP2,SLA,TSNAXIP1,DOK5,PLCB1,SYN2,ADGRL3,PCDHGB6,DNAH7,PIK3R5,OSBP2,LAT2,MKRN3" Drug 4086_DN Trimethadione [127-48-0]; Down 200; 28uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ASIC1,MTUS1,CDC42BPA,PPP4R4,NRP2,SYNJ1,SYNJ2,ARHGEF2,FOXN3,LHX2,LY86,CNTFR,WHRN,NCOR2,CSNK1E,CNTNAP2,BRINP1,MFAP3L,ELN,MTSS1L,ETV1,EZH1,FGFR1,EFCAB2,CGREF1,CSPG5,SEPT9,ICA1,ZNF862,MYT1,NOVA2,SLC11A2,OGG1,PPP5C,MAPK7,SAMD9,ZCWPW1,SLC4A3,SNCA,DDN,JMJD6,IQCE,OSBP2,EVI5" Drug 6894_UP SB 203580; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ASPHD1,LTBP4,CDK13,DNAH17,MAGI1,CRLF1,RAB28,PICK1,CNTFR,JAKMIP2,RUSC2,SGSM2,DTNA,FEM1B,FCF1,YAF2,MBNL2,ETV1,CSPG5,SIGLEC8,ADAMTS13,CACFD1,BACH2,MMP16,MN1,MX1,MYO6,MYT1,GPR85,PFKFB2,PLXNB1,PTPRB,RAD51D,C1orf54,KLHDC8A,DGLUCY,SEMA6D,ARHGAP26,SPTB,RPGRIP1L,TNS1,PDIA2,ZBTB14,NLRP3" Drug 6407_DN 3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "NME5,C1QTNF1,APBB2,ARRB2,CRLF1,CHN2,STOML1,RAB26,HOMER3,WHRN,CNTNAP2,SLITRK5,HDAC9,HDAC4,CNNM1,FAM13A,SYT17,INPP5B,MIA2,NEK1,NF1,CNOT4,PFKFB4,POLG,CNNM2,PTN,PTPRN2,CEP97,SUPT20H,ASAP3,ST6GAL1,COA1,ARHGAP26,SPART,ARHGEF9,MCF2L,EXOC7,IQCE,TRIM2,CRTC1,ZKSCAN5,ZBTB14,NT5M,EPM2A" Drug 3328_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADCY6,ADORA1,GAS7,RGS11,KSR1,TPP1,CPS1,CSF1,RIMS2,SPOCK2,DBT,ERCC2,ZNF589,FHL1,DISC1,GNAL,IRAK3,INPP5B,KCNB1,AFDN,TAGLN3,MX1,MYT1,NF1,NTRK2,PALM,ENPP2,SAMD9,ZDHHC14,TRIM68,ZFHX4,RORB,ASAP3,SNCA,KDM4B,DOK5,ZC3H13,ARHGAP26,HIF3A,CHST5,KCNE5,FAM155A,SLC30A3,SLC17A7" Drug 3776_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADORA1,LTBP4,PKP4,APBB2,PDE8B,RASL11B,MYOM1,SCAPER,GYG2,SEPT7,PCYT1B,CSF1R,RGS6,LRIG1,SEC14L5,CDON,DTNA,EDNRA,SEMA3D,ING4,KAT8,FYB1,GATM,HNMT,C2orf72,KCNJ5,MARK1,MMP16,MYT1,NRCAM,NTRK3,PURG,EMID1,SEMA6D,STUM,SH3BP2,CPEB3,CNKSR2,SLC8A1,SNCA,TNS1,WIPF1,MAP3K12,PHTF2" Drug 3987_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADD2,APAF1,CDC14B,PPP4R4,RASL11B,NRP2,GYG2,LDB2,SCARB1,CNTFR,AKAP7,CNTNAP2,RIMS2,DTNA,ETV1,PTK2B,FGFR1,PRELID3A,NEU3,GRIK5,ATXN2L,IL12A,KIFC3,MARK1,CLDN11,ENPP2,PFKFB4,MAPK3,PTPRN2,BEND5,RGS4,CSRNP3,ZNF821,FUZ,NFASC,PHLDB1,COBL,DOCK9,CDK20,HIRA,VIPR2,ZNF24,ZNF154,DPF3" Drug 1730_UP Ethamivan [304-84-7]; Up 200; 18uM; HL60; HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADCY6,BIN1,AMT,ANK2,ARRB2,ARHGAP33,DLGAP1,TBRG4,IQCK,SEC31B,SPOCK2,ZNF589,FGFR1,BAIAP2,SEMA4D,FLNC,AHDC1,GNG4,GSN,FICD,NXPH3,AGBL5,KCNN1,MID1,OCRL,MAPK3,PTK2,PTN,CCDC40,SAFB,SATB1,ATXN2,BTBD3,SLC11A1,KDM4B,ARHGEF9,PLCB1,GPR161,THRA,CHST5,NPDC1,LAMP5,GDPD5,MPPE1" Drug 5570_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADORA1,KIAA1324,ADGRF5,ALK,AMPH,AMT,GAS7,CDC14B,KSR1,CACNA1I,CAMK2B,CDH2,CSF1,CSF1R,CNTNAP2,RASSF2,INTS1,DUSP9,EDNRA,EGR3,CORO2B,FGFR3,GLYR1,STMN2,ATXN2L,C2orf72,MYO7A,MYT1,TREM2,PDE1C,PDE4B,PFKFB4,ELOVL2,ZMAT4,RFX2,FRMPD1,PDZD2,SYN2,TRIM2,DICER1,HEY1,TRPM2,SLC17A7,NLRP3" Drug 5917_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "NME5,C1QTNF3,TRMT9B,APC,CDK13,SLC4A4,CFAP410,CD86,NCOR2,ARHGEF10,SRPK3,IGSF6,PTK2B,TDRKH,PCLO,SPACA9,IL6R,IPO5,MID1,MMP17,MYO7A,NEK1,NF1,NTRK2,PALM,ZSCAN2,RGS3,TCP11L1,RPS6KA2,CLIP1,ASAP3,FNDC3A,SLC4A3,SLC11A1,SS18,SMG6,RPGRIP1L,PCDHA5,TK2,TNS1,HIRA,SPHK2,SLC30A3,PHTF2" Drug 4533_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "SYT13,CDK13,CFLAR,ST3GAL5,BAIAP3,ARHGAP33,SOCS6,CNTN1,NRG2,CPS1,SH2B1,VCAN,CDON,DTNA,HIPK3,EGFR,IRAK4,ING4,FGF1,FLT1,FYB1,NEU3,GNAL,GPD2,LILRA2,ADAMTS13,KCNJ5,KIT,MATN3,NTRK2,PFKFB2,LRRN3,GRAMD1C,RASGRF1,RET,RASA3,KANSL3,ZNF415,RBM34,ZNF423,RBM26,KIAA1107,UBE3A,KCNAB1" Drug 6963_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ABHD6,ADORA2A,ALK,BIN1,APLP1,DDO,CDC14B,FUBP1,CACNA2D2,DBN1,ANKMY1,DISC1,GLYR1,POLL,PRUNE2,AP4S1,MAP4,MAPT,MGAT3,MID1,AFDN,ADAM22,NTRK2,CCDC40,RPS6KA2,SBF1,CNKSR2,LIMCH1,TSNAXIP1,SPTAN1,TROVE2,PHLDB1,STX1A,VPS13A,ASTN2,TACC1,TNS2,PCDHA6,PARD3,TPM1,CHST5,RUNDC3B,ST7,RNF170" Drug 3584_UP Mesalamine [89-57-6]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ABHD6,ADRA1D,SRPX,APLP1,SEMA4G,CDK13,CFLAR,MTMR2,ARHGEF2,RCBTB2,LHX2,QKI,CREM,CRMP1,VCAN,TBC1D5,BRINP1,EGFR,AASS,SPEG,RRAGB,ANKFY1,TRAF3IP2,TMEM8B,GATM,GLYR1,GSN,GSTM5,VSIG4,DHX35,ADAM22,NTRK3,PRKAR1B,MAPK10,SALL1,CNKSR2,ABLIM3,POGZ,PLCB1,ARC,BEX4,PARD3,NT5M,GDPD5" Drug 4759_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ASIC1,ADCY6,C1QTNF3,ALK,AMPD3,APAF1,APC,APOC1,PPP4R4,NRP2,CFLAR,CFAP410,HAP1,SOCS6,NECTIN3,AATK,CSF1,DMPK,TENM1,VPS13B,EPHB1,FGFR3,FUT9,FYB1,GPR75,GPD1,ICA1,KCNH2,KCNJ5,LAMA2,AFDN,NPY,MAPK7,RPS6KA2,SCN8A,SH3GL3,KANSL3,LIMCH1,UNC5B,ATP10B,TBL1X,ZEB1,VIPR2,SLC30A3" Drug 4818_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "ADRA1D,SRPX,APBB2,NUMB,BCL7A,SYNJ2,MTMR2,AKAP7,ARMC8,MAML1,DAPK3,GIT2,JAKMIP2,MFAP3L,EDNRA,ING4,MTSS1L,ERCC2,FHL1,FAM49B,GAD1,MALT1,CNTRL,KCNH2,IPO5,ZNF862,NF1,RETREG1,TMEM104,WDR25,GTDC1,RPS6KA2,SBF1,TRA2B,SCAF8,EPN2,BTBD7,SNCA,THSD1,BHLHB9,SPHK2,EMSY,KCNAB1,PHTF2" Drug 5626_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-05 5.13E-01 2.97E-04 3.35E-03 44 200 "APAF1,APBA2,GAS7,HIP1R,CLDN10,USP2,TAOK2,QKI,CNN3,CPS1,CREM,CSF1,EDNRA,EGFR,EZH1,REEP2,AGAP2,NSG1,GNAO1,GSTM5,GUCY1B1,SYNPO,ICA1,KCNN1,AFDN,CNOT4,NECAB2,MAPK10,RGS3,RGS12,LIMCH1,SNCA,KIF13A,FAIM2,TSNAXIP1,PEG10,ATP10B,RGL1,SYT5,RPGRIP1L,SLC35G2,XRCC4,SPHK2,UPF3A" Drug 3273_DN Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "AP2A2,ALK,DOC2A,CDC42BPA,APBA2,GAS7,CFLAR,CAMK2G,CACNA2D2,TAOK2,NECTIN3,CSF1R,SOCS5,RCAN1,CNNM1,HSD17B14,STX2,ERCC2,EXTL2,ANKFY1,FAM49B,OGA,INPP5K,USP19,GNG4,SPACA9,GSN,TJAP1,NEK1,NPTX1,SETD4,PRKAB2,PRKAR1B,CNNM2,RGS3,RGS12,GSTCD,RPS6KA2,RASA3,EPN2,DICER1,TRIO,REEP1" Drug 2753_DN Syrosingopine [84-36-6]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "MTUS1,AK2,APBB2,APC,EPB41L5,BCAS1,ARHGDIG,RIPK1,CFLAR,B4GALT6,SLIT2,PLAA,FAM189A2,ARMC8,SOCS5,GREB1,HDAC4,DNAJB6,HIPK3,IQCG,TXNL4A,GLYR1,KITLG,MMP16,NPR2,PCDH9,PIK3R1,NLE1,LRP12,PRKAR1B,ELOVL2,RET,RIC8B,SAFB,SGK1,COA1,NXT2,HIRA,UBTF,VGF,ZBTB38,ST7,PHTF2" Drug 6308_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ASPHD1,SHROOM2,PDE8B,SLC4A4,BACH1,NRP2,CFLAR,SYNJ2,CACNA1G,LHX2,HOMER3,HAPLN1,VCAN,USP6NL,CELSR3,PLXNC1,IGSF6,F5,ST3GAL6,PRELID3A,ZNF44,DENND2A,USP19,ZNF276,GRM8,IL12A,KPNA5,NOVA2,NPTX1,PCDH9,PFKFB2,SAMD9,SNRK,RNASEL,FRMPD1,ST6GAL1,DZIP1,SNCA,TK2,REEP1,SEMA3B,SMIM8,DPF3" Drug 5531_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "BEGAIN,APAF1,APBA2,CDK10,CACNA2D1,CLGN,CPS1,C2CD2,ENTPD4,VCAN,RIMS2,GPRASP1,SPOCK2,FCF1,C3orf18,ENO2,DCTN2,INPP5K,HNMT,INPP5B,LAMA2,LIG4,NPTX1,NTRK3,RETREG1,STRN3,PPP5C,SNRK,ELOVL2,PNMA8A,RPS6KA2,FRMPD1,SLA,PEG10,RBM26,STX1A,MCF2L,TBL1X,WSCD1,HIRA,XRCC4,MAP3K12,EMSY" Drug 5762_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ASIC1,ADRA1D,AP2A2,AMT,APC,ALDH7A1,SYNJ2,MYRF,CBFA2T2,AP4M1,CRLF1,CHN2,RAB28,SULT4A1,NECTIN3,VCAN,PDE4DIP,TBC1D5,RCAN1,MBNL2,EIF4G2,ZNF589,PRELID3A,OGA,GCNT2,SRCAP,GUCY1B1,INPP5B,NF1,NLE1,GAL3ST4,SUGCT,ZNF671,MRAS,ASAP3,FUZ,SLC14A1,SNCA,DDN,CHST8,GPR161,UGT8,TIGD6" Drug 3627_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "AP2A2,NME5,LTBP4,BIN1,KCNAB2,APLP1,PLA2G4C,SLC4A4,CFLAR,BAIAP3,LDLRAD4,SLIT2,CRY2,PDE4DIP,SLC12A6,FAM49B,ZNF44,GPER1,SLC2A6,MAP4,MIA2,MMP17,PLCD1,SMIM7,PRKAR1B,PRKCB,MAPK10,CNNM2,ZSCAN2,KCNIP1,ZNF821,FAM214B,DOK5,IQSEC2,CLSTN2,SUPT5H,VPS13A,EXOC7,KIAA1107,TBCEL,CRTC1,CHST8,PARD3" Drug 2743_DN Stachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ABHD6,AP2A2,APBB2,EPB41L5,PDE8B,ALDH7A1,ARHGEF7,RUNX1T1,QKI,DCAF4,HIPK3,MBNL2,KAT8,FGFR1,FHL1,SEMA4D,FAM49B,SEPT9,MALT1,MSL3,HNMT,TJAP1,INPP5B,MAP4,MMP16,NPR2,NPTX2,RETREG1,PLCD1,MBOAT7,PPP2R2B,PRKAR1B,TCP11L1,SH3BP2,AMBRA1,KDM4B,UNC5B,STX1A,PLCB1,HIRA,DNALI1,ST7,SENP7" Drug 6730_UP Rolipram [61413-54-5]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "AP2A2,AGT,PPP4R4,CDK13,MTMR3,CALB2,CAMK2A,CAMK2B,CD86,CACNA2D2,CHRNA4,TBC1D5,MFAP3L,DMPK,DUSP9,PLXNC1,TENM1,F5,AFF2,PCDH17,RAB30,GNAL,SPACA9,HLF,ELOVL5,MX1,NDP,NF1,NFYA,NPR2,NTRK2,PALM,DCHS2,ENOX1,GSTCD,ST6GAL1,DOP1A,TBCEL,TBL1X,PCDHGA10,TK2,PRDM10,EPM2A" Drug 6644_UP Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ACHE,SPARCL1,LGR5,ATP6V0A1,BMPR1B,TAOK2,AKAP5,ENTPD4,ARHGEF10,BRINP1,MFAP3L,DTNA,EDN1,OLFM1,FLT1,NSG1,OGA,ALDH1L1,C2orf72,ITGA7,KCNJ5,MAPT,MMP16,ADAM22,NPY,GPR85,RETREG1,PPARA,LRRN3,DCHS2,ZSCAN32,ACSS3,SUGCT,ZFP2,RASA3,SH3BP2,SLC11A1,TACR1,DOCK9,TPM1,HIRA,NT5M,JPH3" Drug 3938_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "KIAA1324,ALK,BEGAIN,TRMT9B,BIN1,PDE8B,SEPT7,TPP1,LY86,WHRN,CRY2,GSDME,SV2B,IGSF6,ST3GAL6,FGFR1,DCTN2,NEU3,POLL,GNAL,PRUNE2,GRM8,MGAT3,P2RX7,TREM2,DUSP26,PDZRN4,PPP1R1A,KHDRBS2,ZFHX4,FRMPD1,KANSL3,PKNOX2,KDM4D,SLC11A1,HECW1,TCF4,SZT2,DOCK9,UBE3A,ZNF711,KAT6A,TIGD6" Drug 4275_DN Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ASIC1,NRP2,CFLAR,MYRF,BAIAP3,CFAP410,CBFA2T2,PLEKHB1,CPS1,CRMP1,KLHL3,PARD6A,HIPK3,COQ7,ERCC2,PTK2B,DLC1,TRMO,ZNF276,POLL,SHISAL1,INPP5B,KCNN1,MAPT,LYRM9,NTRK2,RETREG1,BCAS3,RPS6KA2,ST6GAL1,SLC4A3,FAM214B,SNCA,LHPP,ASTN2,CRTC1,GPR161,SLC44A1,CBX5,TNS1,TRIO,TFIP11,HPS4" Drug 6883_DN carmustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "C1QTNF1,AMT,SEMA7A,APBA2,SEMA4G,ST3GAL5,HOMER3,CSF1R,VCAN,DZIP3,PHF14,FAM131B,ZFYVE16,ING4,ETV1,FGF1,FYN,TMEM8B,BACH2,SHISAL1,MEF2C,MIA2,MPP2,ZNF862,C19orf57,SH3TC2,FUZ,FBXO11,ST6GAL1,KDM4D,ZKSCAN3,SPATA7,ST5,SYT1,WSCD1,TCF4,TNS1,VGF,LAT2,TRIM9,REEP1,SLC30A4,GDPD5" Drug 4371_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "LTBP4,BIN1,SEMA7A,DDO,ADAM23,RGS9,CAMK2B,SLC16A4,SEPT7,FAM149A,AATK,ARHGEF10,CNTNAP2,RIMS2,INTS1,SPOCK2,HSD17B14,GPER1,IPO5,MGAT3,MMP17,MYT1,NF1,PCBP3,OGG1,MTRF1L,MAPK7,PTPRO,KCTD17,KLHL11,RPS6KA2,SLC11A1,SNAP25,SNCA,KDM4B,ZNF423,STX1A,R3HDM1,HIRA,KCNK12,EMSY,NT5M,PHTF2" Drug 6897_UP NS-398; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ABHD6,ALCAM,OGT,APOC1,CDK13,STX16,ALDH7A1,KIF1A,ADAM15,CFLAR,SCAPER,CCNT1,C2CD2,CREM,LYPD1,DMPK,EDNRB,FEM1B,IRAK4,BAIAP2,CINP,COPS8,KHK,MMP17,NEK1,NFYA,ZSCAN32,GTDC1,RGS12,SLC22A4,PDZRN3,CDK19,LHPP,CLASP2,NXT2,ST5,PCDHA6,ZNF34,SLC44A1,RPRM,VGF,ZNF24,MAP3K12" Drug 5633_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "NDRG2,LTBP4,BIN1,PPFIA3,PPP4R4,CFLAR,SYNJ1,CFAP410,CAMK2B,CBFA2T2,CLGN,RCBTB2,RAB28,AKAP7,RCHY1,SH2B1,RIMS2,SLC12A6,ING4,ANKMY1,SYT17,GCNT2,SRCAP,MSL3,KCNMB4,CACFD1,RASSF8,TM6SF1,ZNF862,GRAMD1C,ZDHHC14,PREX2,MAPKBP1,DOK5,SPART,TTBK2,PLCB1,CRTC1,FAM155A,ZFP37,ZNF711,ZNF45,ST7" Drug 4169_DN Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "BIN1,GAS7,CFAP410,CACNA1A,ARHGAP33,CNTN1,WHRN,SH2B1,CRY2,SNCAIP,ING4,SCML2,DLC1,SEPT9,ALDH1L1,SRCAP,LYVE1,GSN,SLC2A6,ATXN2L,HNMT,KCNJ5,MAPT,ADAM22,MYT1,SERPINI1,LRP12,PPP2R2B,PRKCB,C1orf54,TRIM68,ZFHX4,TCP11L1,SBF1,SH3BP2,SH3GL3,PREX2,FAM214B,KIF13A,SYT5,WSCD1,CDK20,FLRT2" Drug 7153_DN Pyrithyldione [77-04-3]; Down 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "APBB2,PPFIA3,SLC4A4,CFLAR,ST3GAL5,MTMR3,B4GALT6,NRXN3,ENTPD4,NCOR1,DZIP3,GIT2,C2CD2L,SGSM2,DPH1,EDNRA,IRAK4,F8,ZNF589,IQCG,B4GALNT1,INPP5K,SESN1,POLL,GPD2,GIT1,NF1,PLCD1,ROGDI,RGS3,TCP11L1,WDR37,SMARCD3,TCF4,KIAA0930,TMEM121,TK2,HIRA,UBTF,LMF1,UPF3A,HPS4,ADAMTSL3" Drug 6833_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ASIC1,AP2A2,AGT,BIN1,MARK4,SLC4A4,SYNJ1,CFAP410,USP2,RCBTB2,LY86,CNTFR,CPS1,NCOR2,RIPOR2,RUSC2,CDON,SHANK1,PLXNC1,VPS13B,SPEG,FGF13,ZNF44,PCLO,SPACA9,VSIG4,MID1,ADAM22,MSR1,ZNF862,POU6F1,RIPOR1,CCDC40,ZFHX4,CPEB3,LIMS2,PDZD2,TSNAXIP1,ARC,R3HDM1,AMACR,XRCC4,NT5M" Drug 5398_UP Azacyclonol [115-46-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ASIC1,KIAA1324,LTBP4,AMPH,SEMA7A,APAF1,APBA2,CDC14B,PLA2G4C,CBFA2T2,ARHGAP33,CRLF1,PICK1,CRMP1,EDNRA,EDNRB,FER,CAMKK2,PRELID3A,USP19,GNAL,CNTRL,GRB10,GRM8,GSTM5,RASSF8,ATXN2L,ICA1,LMO2,TAGLN3,MYO7A,NDP,NOVA2,NPR2,C1orf54,ASAP3,KDM4D,SPTB,WSCD1,PIK3R5,UBE2H,WIPF1,ITM2C" Drug 2742_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "MTUS1,CDC42BPA,PKP4,APAF1,APBB2,PPP4R4,SYNJ1,CD86,QKI,CSF1,RUBCN,ZNF337,DGKG,KIAA0753,FCF1,PLXNC1,ING4,NCALD,RRAGB,ZNF589,FHL1,IQCG,INPP5K,LILRA2,IL6ST,LIG4,MAP4,MEF2C,PIK3R1,CCSER2,PILRA,CEP97,ZFHX4,CARF,TMCC1,TSPYL2,CRTC1,ZNF34,TRPS1,SSBP2,FLRT2,ZNF225,PCBP4" Drug 5880_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ADRA1D,N4BP2L1,ADAM23,CFLAR,CBFA2T2,SYNGR3,ARHGEF2,WHRN,CSF1R,VCAN,CTH,ARHGEF4,DAPK3,CNNM1,AASS,DENND4A,GLYR1,MSL3,GPR37,FICD,ICA1,TJAP1,PLCD1,PTCH1,PTPRH,RNASEL,NEK11,EMID1,FAM214B,ZNF334,KDM4B,NMNAT2,ARHGAP26,TSPYL2,DDN,CEP68,COBL,TACR1,SYNE1,SSBP2,HIRA,WNT7A,SLC17A7" Drug 3345_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "BRAP,BIN1,CDC42BPA,CDK13,DNAH17,ATP6V0A1,CHN2,FHL5,CRMP1,PDE4DIP,GPRASP1,TMCC2,MTSS1L,SPEG,FAM198B,ZNF589,FGF12,AGAP2,FLNC,DLL3,TMEM8B,PCDH17,GLYR1,GPD2,GPER1,GSN,ITGAM,MAN2A2,MAPT,KITLG,NF1,STRN3,CEP41,KLHDC8A,ROBO1,RPS6KA2,MRAS,FRMPD1,BTBD7,COA1,LIMCH1,HIF3A,SPHK2" Drug 4474_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "AMPD3,APAF1,NRP2,ST3GAL5,CACNA1I,CFAP410,RUNX1T1,DCLK1,CHN2,TAOK2,LHX2,RAB26,AKAP7,COL9A3,CRMP1,ARHGEF4,ETV1,DLC1,DCTN2,FYB1,ZNF44,SIGLEC8,NEU3,GPD2,GRIK5,LAMA2,LIFR,KITLG,CDK18,PFKFB4,ELOVL2,ZSCAN2,SUGCT,FBXW7,ZNF671,KANSL3,TSNAXIP1,PHLDB1,PLCB1,MCF2L,TIMP4,TNS1,FLRT2" Drug 2813_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "ADORA1,SEMA6A,APLP1,PPFIA3,PLA2G4C,ATP2A2,SLC16A4,FOXN3,ASIC3,TAOK2,RCHY1,ABCG1,ARHGEF10,PHF14,DNAH9,MBNL2,ENO2,STX2,EZH1,ZNF589,INPP5K,TDRKH,GSN,ACOT7,MBNL1,KITLG,ADAM22,NF1,PCDH9,MTRF1L,SNRK,WDR25,PTPRO,SH3GL3,SLC22A4,SNCA,HECW1,KIAA1107,TBCEL,TRIM2,PCDHGA10,EVI5,FIP1L1" Drug 4269_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "APC,CACNA1I,CD38,CHRNA4,EPS15L1,RGS6,VCAN,DGKB,EDNRA,MRNIP,RASGRP2,EPHB1,F5,REEP2,CORO2B,FYB1,ADAM28,GNG4,GPD1,GRM8,ICA1,LMO2,MSI1,TAGLN3,MYT1,FXYD7,NOVA2,PDE4B,LRRN3,PRPH,PTPRB,RGS4,DZIP1,SLC8A1,CXXC4,ARHGAP26,SSTR2,PLCB1,TACR1,MCF2L,KLHL4,TK2,DPF3" Drug 6757_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "SEMA6A,AQP6,MYOM1,BMP7,MYRF,BAIAP3,SLC16A4,DLGAP1,CHRNA4,NRXN3,GAL3ST1,CSF1,LRIG1,PPP1R16B,DMPK,DRP2,ING4,SRPK3,EFCAB2,ERAP1,RUNDC3A,GRIK5,KCNJ5,PACRG,MT1M,MYH3,NPY,PPP1R1A,PTPRH,MARCH1,C1orf54,PNMA8A,SCN2B,PPM1E,CNKSR2,SNCA,CDK19,SYP,SYT5,THRA,TK2,BHLHB9,NT5M" Drug 5235_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "AGT,NME5,BIN1,APBB2,APC,APOC1,BCAS1,CLGN,SOCS6,B4GALT6,NECTIN3,CRMP1,CTH,RASSF2,RUSC2,MBNL2,EPB41L2,PTK2B,FGFR1,GLYR1,STON1,GPER1,GPR37,KCNN2,MEF2C,MYO7A,NTRK2,PCDH9,LRP12,CLIP1,SH3GL3,ST6GAL1,LIMCH1,TSNAXIP1,ATP10B,STX1A,EXOC7,PCDHGA10,BEX4,RUNDC3B,HIRA,PLPPR2,EPM2A" Drug 1213_UP 17-DMAG; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 5.27E-01 3.01E-04 3.39E-03 43 194 "OSBPL1A,PPFIA3,PDE8B,SLC4A4,KIF1A,CFLAR,CFAP410,CHN2,ARMC8,WHRN,COL9A3,ENTPD4,ECM2,ING4,OGA,USP19,MSL3,PRUNE2,DIDO1,ICA1,SHISAL1,MMP16,NELL2,OXTR,PPARA,PTN,CCDC40,GAL3ST4,RGS4,PNMA8A,SUPT20H,HSPA4L,SMARCD3,PDZD2,ZC3H13,IQSEC2,COBL,TRIM2,CABIN1,TNS1,HPS4,SMIM8,FXR1" Drug 3325_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.23E-05 5.40E-01 3.08E-04 3.47E-03 42 188 "AK2,PPFIA3,CDC14B,CFLAR,FOXN3,CSF1,GREB1,TBC1D5,JAKMIP2,RHOBTB1,PARD6A,E2F5,RASGRP1,SUGP2,EGR3,STX2,FGFR1,FAM49B,CGREF1,SEPT9,RAB30,CACFD1,MAP4,MIA2,MYO9A,OCRL,PIK3R1,MBOAT7,PRKAR1B,CEP97,RET,RGS12,GSTCD,TCP11L1,SYBU,SIRT2,SMARCA4,ERC1,POGZ,PLCB1,EXOC7,RPGRIP1L" Drug CID000326807 NSC298883 Stitch 1.24E-05 5.44E-01 3.10E-04 3.49E-03 25 89 "SYNJ1,RHBDL1,CLCN3,MYL6B,CLTC,CRMP1,CSF1R,SNAP91,DNM1,DNM1L,STX2,GRM2,GRM8,MYO5A,NTRK2,P2RX7,RAD17,STX1B,SNAP25,STX1A,SYN1,SYN2,SYP,SYT1,SLC17A7" Drug ctd:C008261 lead acetate CTD 1.25E-05 5.46E-01 3.11E-04 3.50E-03 269 1862 "RALGAPA1,DGCR6,KCNH8,SYN3,ACHE,ADCY8,ADORA1,ADRA1D,AP2A1,OSBPL6,WDR35,SEMA6A,ALCAM,ANK2,APAF1,APOC2,LGR5,MADD,ARHGDIA,CDK13,CHID1,ALDH7A1,KIF1A,BCHE,BID,PROM1,LDLRAD4,CA8,KALRN,CAMK2A,CAPN3,CARS,CD86,SCARB1,CDH2,CLGN,CLCN3,CLTC,ABCG2,MAP4K4,AKAP7,COL4A5,COL9A1,COL9A3,COL11A2,NCOR2,CSF1R,CSF2RA,LRIG1,PDE4DIP,CNTNAP2,UBXN2A,GREB1,USP6NL,SEC14L5,CYBB,HDAC9,GPRASP1,ARHGAP24,ZFYVE16,EARS2,DAPK1,DBN1,HEPH,KIF19,GRIN3A,CDON,DPYSL2,ARRDC4,DNAJB6,EDNRB,HEYL,FRY,CELSR3,EGFR,EIF4G2,USPL1,EPHB1,ENPP6,ERCC2,IGSF6,F5,TBC1D16,ZMYND10,FCGR3A,FCGRT,FGF1,FGFR1,SEC23B,PCYOX1,EVL,EFCAB2,JKAMP,ATP6V1H,NSG1,MPP6,FYN,NEURL4,GAA,B4GALNT1,ERAP1,MTHFD2,DISC1,GATM,PPARGC1A,LYVE1,DBF4,TNRC6A,GLUL,CBX1,LOXL3,GNAO1,LNX1,GPD1,GRB10,GRIA2,GRIK5,GRIN2C,GRIN2D,GRM8,GSTT2,GUCY1A1,GUCY1B1,MAP4K5,FRMD3,ACOT7,HNF4G,IGFBPL1,CFAP126,IGF1,LRRCC1,IL6R,IL12A,INPP1,KCNJ5,KCNJ16,KHK,KIF5A,LAMA2,CAMK2N2,LIG4,SMAD1,SMAD9,GPR155,MAP2,MAPT,MAT2A,MATK,MBP,MEST,MIA2,KITLG,MID1,MITF,BLOC1S2,MT1M,MYCN,MYO6,NCAM2,NEFM,NEFH,NFE2L2,ALDH1L2,NFIX,NFYA,SLC11A2,NTRK2,P2RX7,P2RY1,ZNF827,PAX6,ENPP2,PDPK1,ZNF655,SNX10,RETREG1,PCDH18,ZNF426,SCHIP1,FA2H,PPARA,PPP5C,PRKCB,MAPK3,MAPK4,MAPK9,MAPK10,PRPSAP2,MASP1,RELN,KLK6,LAMA1,MTMR10,SPDL1,PTPRN,PTPRO,PEX2,ACSM5,TMEM255A,RET,ERI2,RNASE1,RNASEL,ROBO1,ROBO2,GLDN,MAP6D1,STX1B,RYR3,S100B,SCN7A,HES6,SGK1,FERMT1,SHMT2,FNDC3A,SLC2A5,LIMS2,SLC6A8,SLC6A11,TRIM67,SLC12A2,BTBD7,SNAP25,SNCA,SOX3,SP2,HECW1,MYCBP2,SPP1,NFASC,PBLD,THSD1,STX1A,KANK1,JMJD6,SYN1,ARC,SYP,SYT1,TPCN2,PCDHGB6,SYNE1,PCDHB9,SLC19A3,FRYL,HIF3A,ITGB3BP,BEX4,ANKRD24,TNS1,RUNDC3B,CA14,TSC1,UBC,UGT8,VGF,VLDLR,LAT2,WNT7A,EVI5,CIAPIN1,NAV3,SLC17A7,KCNAB1,PLD4,RTN4,KAT6A,GJC2" Drug 6896_UP scriptaid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.28E-05 5.61E-01 3.19E-04 3.60E-03 40 176 "ADRB2,NME5,APBB2,ARNTL,ST3GAL5,SPAG9,SYNGR3,PDE4DIP,CNTNAP2,CTH,DAPK3,PLPPR4,SLC12A6,MBNL2,TAOK3,PDLIM5,CSPG5,SPACA9,ACOT7,FAM69A,ITGA7,LSS,MAP2,MAPT,MEF2C,MYO6,NEK1,NFYA,PCDH9,PFKFB2,SERPINI1,RGS4,WDR47,SOX15,SPTAN1,ELOVL4,RGL1,SYT1,RUNDC3B,SSBP2" Drug CID005326793 Pe v Stitch 1.31E-05 5.73E-01 3.26E-04 3.67E-03 38 164 "APAF1,APOC1,BID,PRC1,DYNC1I1,KMT5B,ENO2,EZH1,FCGRT,FKTN,PPP1R1B,CELF1,AHDC1,GHR,PPARGC1A,TCERG1,CBX1,KAT7,PACSIN2,IGF1,NF1,NPY,OGG1,OPA1,PPP2R2B,MAPK9,MAPK10,PTN,QDPR,ATXN7,FOXRED1,SIRT2,SST,SIRT1,MAP3K12,HPS4,FXR1,JPH3" Drug 4557_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AP2A2,APAF1,SLC4A4,ADGRB3,CFLAR,SYNJ2,GYG2,C5,IL33,HAP1,CBFA2T2,PLEKHB1,WHRN,ABCG1,CSF1,CTH,ARHGAP32,PITPNC1,SV2B,ING4,ETV1,FYB1,SRCAP,GPER1,JAK2,LIG4,MMP16,ADAM22,NOVA2,PDE4B,PDE4D,PLCD1,SMOX,GRAMD1C,PTPRH,GAL3ST4,FAM214B,HECW1,ARHGAP26,ATP10B,TCF4,R3HDM1,TPM1" Drug 6696_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "LTBP4,ALK,APAF1,APC,ADGRB2,BMP7,SYNJ2,SCAPER,ENTPD2,TAOK2,ARMC8,HAPLN1,CSF1R,VCAN,RIPOR2,JAKMIP2,MFAP3L,DTNA,EDIL3,EDN3,HIPK3,MBNL2,PLXNC1,ING4,ZNF589,FGFR1,GLYR1,GPER1,GRM8,IL6R,KITLG,NF1,NLE1,ELOVL2,ZSCAN32,CXXC4,ZSWIM8,HECW1,TROVE2,COBL,UBTF,ZNF24,GAN" Drug 2906_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "OGT,AQP6,PPP4R4,PDE8B,MPDZ,BMP7,CAMK2B,KCNAB3,CLGN,TAOK2,ABI3BP,VCAN,DZIP3,ELN,CORO2B,FCGRT,KAT8,FGFR3,AFF2,PRELID3A,ADAM28,GNG4,STON1,GSN,ATXN2L,ITPKA,KIFC3,NTRK2,ENPP2,PLCD1,ANKRD6,PREX2,EPN2,LIMS2,SPTAN1,SPART,MTCL1,TNS1,KCNE5,CLIP2,ZNF154,SLC17A7,KCNAB1" Drug 6739_DN Hemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "APOC1,PDE8B,MARK4,ALDH7A1,ADAM23,CACNA1I,WHRN,MFAP3L,SPOCK3,SUGP2,AASS,MRNIP,MTSS1L,FYB1,DENND2A,TMEM8B,LYVE1,LPAR4,ICA1,MAPT,MEIS1,NF1,PRKAR1B,MAPK7,GRAMD1C,PTN,ZSCAN32,RIPOR1,KIRREL1,FBXW7,TSNAXIP1,SPTAN1,RBM26,LHPP,THSD1,PHLDB1,RPGRIP1L,DOCK9,PCDHA5,TRIO,WIPF1,MAP3K12,HPS4" Drug 3923_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AP2A2,LTBP4,AMPD3,APLP1,PLA2G4C,MARK4,SLC2A11,ATP6V0A1,RIPK1,ARHGEF1,CBFA2T2,FOXN3,SOCS6,B4GALT6,TAOK2,RCHY1,MAML1,DBN1,DCTN1,LYPD1,DTNA,KHDRBS3,GALC,SRCAP,GLYR1,ADAMTS13,KCNN1,ADAM22,ZNF862,PCDHGC3,PLCD1,SLC25A23,SMIM7,NKAIN1,MSANTD2,ZNF821,ARHGAP26,ZBTB43,TROVE2,PARD3,TRIO,ZKSCAN5,PLPPR2" Drug 6822_UP Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AP2A2,BEGAIN,AMT,SYNJ1,CA4,CBFA2T2,PICK1,NECTIN3,DCAF4,SPOCK2,RUSC2,ECM2,EDN1,VPS13B,ERCC2,ETV1,KAT8,PDLIM5,FYN,CSDC2,SPACA9,GRM2,HLF,ITGAM,KCNQ3,AFF1,NOVA1,NPTX2,PDE1C,C19orf57,RGS12,TCP11L1,FAM214B,SNCA,ZNF423,SYN2,SYP,WSCD1,GPR161,RUNDC3B,WIPF1,XRCC4,KCNAB1" Drug 1630_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "BIN1,CDC42BPA,KCNAB2,ATP6V0A1,MTMR3,GYG2,HIP1R,HOMER3,PICK1,CREM,SPOCK2,LYPD1,DMPK,TENM1,ERBB2,EZH1,IQCG,RAB40B,STON1,GPER1,GRIK5,LMO2,NF1,PDPK1,PTCH1,ZCWPW1,CLIP1,RXRA,ZNF821,SH3BP2,SMARCC2,SPTAN1,ZBTB43,TACC1,EXOC7,TBL1X,SMG6,TRIM2,WBP2,VLDLR,MAP3K12,EMSY,MPPE1" Drug 5797_DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ADD2,ADRA1D,MPDZ,C5,NRG2,CPS1,HAPLN1,CRY2,CSF1R,C2CD2L,LYPD1,DYNC1I1,TOM1,DENND4A,RRAGB,FGF1,FGFR1,CINP,PDLIM5,TRAF3IP2,PCDH17,KCNMB4,MUM1,ICA1,IL6ST,MAPT,ZNF862,MAPK7,RGS4,PREX2,SIRT2,CCDC88A,SMARCD3,DDN,JMJD6,SYN2,MCF2L,SYNE1,TMEM121,TK2,ZKSCAN5,UGT8,GAN" Drug 4664_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AMT,FAM131A,SHROOM2,SCARB1,SYNGR3,FOXN3,TAOK2,ARHGEF10,PDE4DIP,CNTNAP2,DZIP3,DCAF8,DAPK3,EXOG,DMPK,MBNL2,ETV1,SEMA4D,SYT17,MSL3,IFI16,FAM69A,MMP16,NDP,CNOT4,PCDH9,PRKAB2,SUGCT,CSRNP3,ATXN7,SUPT20H,FUZ,ST6GAL1,IQSEC2,PHLDB1,SUPT5H,ASTN2,TCF4,AP4E1,BHLHB9,CABIN1,SSBP2,EMSY" Drug 7318_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "APC,GAS7,BAIAP3,CACNA2D2,CSF1,PDE4DIP,HDAC9,EIF4G2,COQ7,DLC1,FGF1,FLT1,GAD1,ZNF276,DIDO1,SPACA9,GRIK5,FAM69A,INPP5B,LYRM9,MYO6,PDE1C,ENPP2,CCSER2,PURG,MAPK3,RFX2,KCTD17,NEK11,SH3BP2,AMBRA1,FAM214B,SLC11A1,PDZD2,ZHX3,LHPP,THSD1,SS18,DOCK9,CABIN1,XRCC4,SPHK2,DPF3" Drug 5452_UP Procarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ADRA1B,FAM135A,BIN1,APBA2,KCNAB2,APLP1,RGS20,SLC4A4,N4BP2L1,ST3GAL5,SCAPER,USP2,DLGAP2,SULT4A1,CRMP1,DCAF4,HS3ST2,HIPK3,ING4,LRRC17,ERCC2,GATM,GRB10,KCNN1,KCNQ3,MMP17,PDE4A,ENPP2,PLCB2,PLCD1,SAMD9,PID1,C1orf54,CCDC25,RPS6KA2,CNKSR2,FAM214B,PEG10,ZEB1,CRTC1,FAM155A,PLSCR4,DPF3" Drug 7393_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ADCY6,AMPD3,CDK10,SLC4A4,EIF4G3,CACNA2D1,KALRN,CACNA2D2,SLC4A8,CRMP1,PARD6A,DPH1,CNNM1,ING4,COQ7,ETV1,FGFR1,DENND2A,ZNF276,GLYR1,PRUNE2,GPER1,DHX35,SHISAL1,FAM69A,LMO2,KITLG,PDE4B,PPP5C,ZDHHC14,EMID1,TRAPPC13,SUPT20H,FUZ,PPP4R3A,ARHGEF40,ZSWIM8,SPTAN1,TRIM2,DOCK9,AP4E1,XRCC4,UBE3B" Drug 4971_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "NDRG2,SPARCL1,PPFIA3,ARRB1,SLC2A11,ALDH7A1,CAST,HOMER3,CNTN1,FAM149A,WHRN,VCAN,GREB1,MFAP3L,ZNF589,FGF1,AGAP2,ALDH1L1,GFER,GLYR1,MSL3,GSTM5,KCNH2,KIT,LSS,MEF2C,RETREG1,NLE1,PLEC,NECAB2,RETREG2,PPP5C,ZFHX4,CARF,HECW1,ZBTB43,ST5,WSCD1,TRIO,HIRA,ZBTB14,SPHK2,SENP7" Drug 6424_DN F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AMH,OGT,EPB41L5,APOC1,PPP4R4,ZBTB10,EIF4G3,CFLAR,SCAPER,CA12,CLGN,RAB26,COL4A5,NECTIN3,CSF1R,PDE4DIP,DNAH9,DLC1,ALDH1L1,COPS8,KCNMB4,STON1,GPR37,HNMT,ICA1,MAN2A2,MEIS1,MPP2,ADAM22,ZCWPW1,KCTD17,TCP11L1,EMID1,LIMS2,LIMCH1,KIF13A,KDM4B,SPTAN1,ITPRID2,THSD1,KIAA0930,WRN,RNF170" Drug 6417_DN CGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AP2A2,TRMT9B,APC,PPFIA3,ALDH7A1,CBFA2T2,RCBTB2,RAB28,TPP1,SULT4A1,RAB26,CRY2,CNTNAP2,SLITRK5,SPOCK2,PDLIM5,TRAF3IP2,DISC1,SRCAP,GNG4,ELOVL5,ADAM22,ZNF862,NPR2,FSD1,MAPK7,PTCH1,TRAPPC13,SBF1,FBXO11,KDM4B,SPTB,DDN,VPS13A,TMEM121,CABIN1,OSBP2,PLPPR2,WNT7A,KLC2,XRCC4,SEMA3B,KCNAB1" Drug 3812_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ADGRF5,LTBP4,APC,ARHGDIG,ATP2B2,AZGP1,CACNA1I,KALRN,SULT4A1,SUSD5,IPCEF1,PDE4DIP,EGR3,ERBB4,OLFM1,PDLIM5,GFER,GRM2,KHK,MMP16,NDP,NOVA2,NPTX2,NTRK2,GPR173,SERPINI1,PNMA3,PPP2R2B,PRKAR1B,WDR25,RASGRF1,GAL3ST4,RNASEL,SEMA6D,SLC2A5,PKNOX2,SLC8A1,CXXC4,FAIM2,MCF2L,TRO,CA14,ZNF154" Drug 5834_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ASPHD1,ASIC1,AMPD3,AMT,PPP4R4,CFLAR,CCK,B4GALT6,CNOT8,CPS1,CTH,SEC14L5,GIT2,CNNM1,ETV1,DLC1,FDFT1,TRMO,SEPT9,GLYR1,ICA1,KIT,MAN2A2,AFDN,NF1,NTRK2,CCSER2,STRN3,MAPK3,NEK11,FNDC3A,DZIP1,SLC2A5,ARHGEF40,SMARCA4,MYH15,STX1A,AP4E1,BEX4,CABIN1,NDRG4,KCNAB1,JPH3" Drug 1532_DN Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "CDC42BPA,APBB2,PPFIA3,ARHGDIG,SLC4A4,KIF1A,CFLAR,ST3GAL5,MTMR2,CBFA2T2,SRSF11,FAM189A2,CREM,DCAF8,TBC1D5,DAPK3,TOM1,HIPK3,EGFR,DENND4A,FER,FGFR1,BAIAP2,AHDC1,CRCP,RAB30,TJAP1,INPP5B,MBD1,MIA2,NEK1,ZCWPW1,NEK11,MCMBP,TCP11L1,ZNF821,SPTAN1,CDK19,PLCB1,NPL,PLPPR2,HPS4,ACTR3B" Drug 2160_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "MTUS1,AMPH,APAF1,APOC1,CDC14B,SEMA4G,MYOM1,CACNA1I,AKAP7,SEC14L5,RUSC2,EGFR,LRRC17,F5,GALC,ERAP1,ALDH1L1,SRCAP,LILRA2,SLC2A6,DHX35,ICA1,IL6ST,KCNB1,MAP4,SCAMP5,PLCD1,BCAS3,PTPN13,RIPOR1,NEK11,MAP6D1,GALNT10,EPN2,KBTBD4,KIF13A,RBM34,ATP10B,TBL1X,RUNDC3B,MKRN3,LAMP5,SLC17A7" Drug 2189_UP Acacetin [480-44-4]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ALK,PRX,PLA2G4C,BMP7,FUBP1,CACNA1I,LDLRAD4,CFAP410,SLC16A4,CDH2,CREM,ABCG1,DZIP3,DNAJB6,E2F5,ANKRD46,CDKL3,SH3YL1,FLT1,GLYR1,RNFT2,HAS2,IL12A,KIF5A,AFDN,MT1M,ZNF862,SMIM7,CEP41,WDR25,RPS20,SH3BGR,MYH15,HECW1,ZBTB43,SPART,PHLDB1,JMJD6,CBX5,RUNDC3B,FAM155A,PRDM10,KCNAB1" Drug 4418_DN Ethionamide [536-33-4]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AMPD3,SEMA7A,GAS7,PLA2G4C,ALDH7A1,KIF1A,SYNJ1,CAMK2B,FOXN3,CNTFR,RASSF2,SPOCK2,RUSC2,VPS26C,FGF13,PRKAG2,ALDH1L1,GLYR1,MSL3,POLL,PCLO,CNTRL,ATXN2L,KCNN1,LIG4,LMO2,ADAM22,NF1,MTRF1L,PPP5C,CARF,PKNOX2,SLC11A1,BTBD7,PDZD2,RGL1,WSCD1,HEY1,CDK20,ZKSCAN5,HIRA,EMSY,SLC17A7" Drug 433_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "NDRG2,MPDZ,BMP7,SYNJ1,RAB29,CHN2,CHRNA4,CNR1,ABCG1,ARHGEF10,C2CD2L,ACSL4,FER,AGAP2,AFF2,GAD1,DISC1,PRRC2B,GUCY1B1,FAM69A,MITF,MMP16,MYO9A,PCBP3,PPARA,MINDY2,MASP1,TMEM104,DCUN1D2,TCP11L1,CSRNP3,ASAP3,SLC9A5,SPTB,SPART,VPS13A,COBL,TBL1X,TCF4,DMXL2,LMF1,GDPD5,MPPE1" Drug 1573_UP Fendiline hydrochloride [13636-18-5]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "NDRG3,NDRG2,OSBPL1A,BCL7A,CFLAR,BMP7,CAST,PICK1,IQCK,LETMD1,SEC31B,ENTPD4,SH2B1,C2CD2L,EXOG,TUBD1,ANKMY1,ATP2C1,OGA,TRAF3IP2,ALDH1L1,MALT1,HTATSF1,PRRC2B,ICA1,KCNN1,MBD1,NEFH,P2RX7,MINDY2,CNNM2,PTN,TRIM68,RNH1,RPS6KA2,SGK1,PPP4R3A,KBTBD4,ELMO2,ZHX3,UPF3A,AAAS,DPF3" Drug 3969_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "BIN1,APAF1,APOC1,FUBP1,CACNA2D1,DLGAP2,CRMP1,GSDME,ING4,ERBB4,ETV1,ANKMY1,CAMKK2,ALDH1L1,GDF9,POLL,GNAO1,GPER1,PCLO,SHISAL1,JAK2,LIFR,KITLG,AFDN,MMP16,MPP2,NTRK2,TREM2,PNMA3,C19orf57,CEP41,GRAMD1C,ZSCAN2,RPS20,KCNIP1,CLIP1,ASAP3,SLC2A5,PKNOX2,PDZD2,DOCK9,CHST5,FLRT2" Drug 5427_DN Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "NDRG3,NME5,AK2,ALCAM,APC,MARK4,SCAPER,KYAT1,CBFA2T2,QKI,ARHGEF6,CRY2,RUSC2,DTNA,FHL1,POLL,GPER1,GRIK5,ATXN2L,MATK,ADAM22,NF1,NTRK2,SERPINI1,NLE1,PLXNB1,LRP12,ELOVL2,SYBU,COA1,TSNAXIP1,ERC1,PLCB1,ASTN2,PARD3,VIPR2,KCNK12,ZFP37,ZBTB14,SPHK2,GDPD5,PHTF2,SENP7" Drug 2386_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "PROM1,HAP1,KRIT1,CBFA2T2,CHRNA4,TPP1,RUBCN,SEC14L5,GSDME,HEYL,EIF4G2,VPS13B,MTSS1L,CDKL3,FGFR1,EFCAB2,FAM49B,POLL,LILRB4,ICA1,C2orf72,JAK2,KCNJ5,KHK,TREM2,ENPP2,GPR85,PTN,RET,RGS3,TCP11L1,ASAP3,SPP1,PEG10,SS18,DNMBP,PDLIM2,CRTC1,AP4E1,GPR161,TPM1,SSBP2,UBE3B" Drug 6244_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ARNTL,ADAM15,RGS11,CDH2,VAX2,DCAF8,DMPK,RCAN1,DTNA,SUGP2,EIF4G2,STX2,ATP2C1,USP19,GLYR1,GLUL,CNTRL,PADI2,HMGCR,INPP5B,JAK2,LIG4,MPP2,ADAM22,ZNF862,PDE4A,RETREG1,LRP12,PPP5C,CNNM2,ELOVL2,SAFB,SEMA6D,ARHGAP26,NSFL1C,ARC,EXOC7,WBP2,KLC2,XRCC4,MAP3K12,PHTF2,GAN" Drug 4829_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "PDE8B,NRP2,FOXN3,TPP1,NECTIN3,SPOCK2,RUSC2,EGR3,PLXNC1,VPS26C,RRAGB,FGF13,ALDH1L1,PRUNE2,ICA1,JAK2,KPNA5,MEF2C,NELL2,ENPP2,PLCD1,PPP5C,RGS12,KLHDC8A,SEMA6D,SYBU,PKNOX2,SNCA,KDM4B,CDK19,CLSTN2,SS18,ARC,WSCD1,TRIM2,PCDHGA10,DOCK9,AP4E1,FAM155A,LAT2,ZFP37,ZBTB14,MKRN3" Drug 4577_UP Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "RALGAPA1,AGT,EP400,GAS7,CFLAR,RAB29,KRIT1,LARGE1,CHN2,QKI,CREM,PDE4DIP,CNTNAP2,PHF14,GIT2,RCAN1,SUGP2,KCTD3,IRAK4,ETV1,TRMO,DENND2A,SOX21,JAK2,NF1,NNAT,GPR85,PIK3R1,MINDY2,SNRK,FBXW7,CLIP1,PPP4R3A,FAM214B,BTBD7,KDM4C,SS18,ASTN2,TCF4,PCDHA5,GPR161,SLC17A7,PHTF2" Drug 4098_UP Furazolidone [67-45-8]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "AGT,BBOX1,BEGAIN,APC,GAS7,N4BP2L1,ADGRB1,BAIAP3,CAMK2B,SLC16A4,ARHGAP33,NRXN3,CSF1,C2CD2L,HEYL,SRPK3,RASGRP2,ANKMY1,FAM198B,HNMT,MAN2A2,MAPT,MMP16,MYO7A,NPTX1,NTRK3,PALM,PPP1R1A,MARCH1,CCDC40,KHDRBS2,RNASE1,SCN2B,PKNOX2,HECW1,RBM26,TACR1,KLHL4,HIF3A,THRA,CHST5,UBE3A,FAM13C" Drug 2649_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "BIN1,APOC1,ST3GAL5,CLCN3,QKI,ARMC8,COL4A5,PDE4DIP,GIT2,FBXL5,DTNA,EIF5,ING4,STX2,FGFR1,FHL1,FAM49B,DISC1,MSL3,GPER1,DHX35,KCNH2,MAP4,MBNL1,GIT1,NF1,RGS3,RNASEL,ZNF821,SGK1,AMBRA1,FBXO11,PEX26,INTS9,SOX3,TROVE2,SS18,CEP68,ASTN2,TACC1,HIRA,WRN,MPPE1" Drug 5109_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "MTUS1,FAM131A,BCL7A,RCBTB2,PLAA,ARMC8,CREM,SLITRK5,ARHGEF4,DBT,PARD6A,EDNRA,FEM1B,DENND4A,ETV1,CSPG5,COPS8,PRRC2B,PCLO,SLC2A6,HNMT,AGFG1,IL6ST,INPP5B,KPNA5,MAPT,SCAMP5,MITF,NFIX,STRN3,APTX,PTN,CSRNP3,LIMS2,LIMCH1,PEG10,SYT1,IQCE,TCF4,TMPO,LMF1,ZBTB38,EVI5" Drug 5076_DN Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "TRMT9B,KCNAB2,APC,NCOA1,BACH1,HOMER3,CSF1R,CSNK1E,C2CD2L,PARD6A,EXOG,FAM13A,EGFR,ETV1,ZNF589,SEMA4D,USP21,CSPG5,GPER1,BACH2,MPP2,MX1,NF1,PDE4D,STRN3,POLG,TMEM104,ZDHHC14,GAL3ST4,RPS6KA2,MAPK12,SCN8A,ZFP30,SH3BP2,PEX26,SMARCD3,SPTAN1,TK2,UBTF,NDRG4,SPHK2,MAP3K12,DPF3" Drug 4634_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "ASPHD1,ADCY6,MTUS1,KCNAB2,GAS7,SLC4A4,ST3GAL5,CACNA1G,CFAP410,ARHGEF2,SOCS6,TPP1,RAB26,HAPLN1,VCAN,PDE4DIP,SIGLEC8,SRCAP,TDRKH,HNMT,ICA1,SHISAL1,KCNJ5,GIT1,CLDN11,PTCH1,C1orf54,KLHL11,SLC11A1,HECW1,ARHGAP26,ELOVL4,ASTN2,TACR1,TBCEL,TCF4,DOCK9,SLC44A1,SSBP2,FLRT2,VIPR2,NAV3,SLC17A7" Drug 5590_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.38E-05 6.03E-01 3.36E-04 3.79E-03 43 195 "C1QTNF3,APBA2,APBB2,EPB41L5,FAM131A,MARK4,NCOA1,ATP6V0A1,CFLAR,GYG2,KRIT1,DZIP3,GPRASP1,FGFR3,GHR,MALT1,RAB30,MSL3,CNTRL,CACFD1,BTN2A1,HNMT,MATK,KITLG,NF1,RETREG1,SLC25A23,PRKAR1B,WDR25,ZDHHC14,RBM34,ZHX3,SPTAN1,CLASP2,EXOC7,TBCEL,TPM1,CDK20,PLPPR2,NDRG4,HPS4,MPPE1,ACTR3B" Drug 2499_UP Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 6.19E-01 3.45E-04 3.88E-03 42 189 "RALGAPA1,AMH,DNAH17,MYOM1,RIPK1,LDLRAD4,CD86,SULT4A1,CREM,ENTPD4,CRYM,SIPA1L1,PDE4DIP,PPP1R16B,GPRASP1,EXOG,TOM1,DNAJB6,SEZ6L2,MBNL2,EGR3,CDKL3,KCND1,AFDN,ZNF862,CCSER2,PDZRN4,CEP41,RBBP6,RFX2,KCTD17,NEK11,RPS20,SGK1,SNCA,SPP1,STX1A,JMJD6,ANKRD28,CBX5,LMF1,PRDM10" Drug 5248_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-05 6.19E-01 3.45E-04 3.88E-03 42 189 "ALCAM,SCAPER,CAMK2G,MAGI1,TAOK2,QKI,NECTIN3,LRIG1,GREB1,DOCK4,RCAN1,DTNA,EPB41L2,PDLIM5,OGA,TRAF3IP2,SRCAP,GHR,TXNL4A,GLYR1,RAB30,INPP5B,JAK2,MEIS1,KITLG,MMP16,SLC11A2,PIK3R1,MBOAT7,PKIA,CEP97,BTBD7,PHLDB1,PLCB1,TMPO,KAT6B,TRPS1,SSBP2,ZBTB14,EPM2A,ST7,RNF170" Drug 3084_UP Clioquinol [130-26-7]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 6.19E-01 3.45E-04 3.88E-03 42 189 "SYN3,BEGAIN,BIN1,FAM131A,PRX,PLA2G4C,PDE8B,MPDZ,CACNA1I,CREM,PDE4DIP,ARHGAP32,RCAN1,CELSR3,GFER,PCLO,SLC2A6,MAP4,MGAT3,MT1M,MX1,NTRK2,OPRL1,CCSER2,MTRF1L,RELN,PTPRN2,RIPOR1,PID1,ZFHX4,SH3BGR,SLC6A8,SNAP25,ARHGAP26,SPTAN1,DDN,TNS1,FLRT2,VGF,CLIP2,SLC17A7,PCBP4" Drug 1742_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.41E-05 6.19E-01 3.45E-04 3.88E-03 42 189 "ADCY6,MTUS1,ALCAM,CDK13,MARK4,RIPK1,CFLAR,CD86,SOCS6,FAM189A2,ARMC8,CSF1R,PPP1R16B,DOCK4,KIAA0753,FAM13A,MRNIP,ACSL4,MALT1,MPP2,NF1,PALM,PDE4B,GPSM2,SMOX,MBOAT7,RNASEL,SATB1,SH3BP2,BTBD3,LIMS2,USP33,TSPYL2,SAMSN1,PLCB1,EXOC7,TBL1X,SLC44A1,PARD3,UCHL1,GDPD5,MPPE1" Drug ctd:D008044 Linuron CTD 1.43E-05 6.26E-01 3.48E-04 3.92E-03 32 129 "ACTN1,DOC2A,DPP10,APAF1,BMPR1B,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CAMK2B,CAMK2G,DPP6,EGFR,ERBB2,ERBB4,FYN,STMN2,GRIA2,IGF1,NF1,NRCAM,NTRK2,RELN,ROBO1,RXRA,HES6,NLGN1,UNC5B,STXBP1,SYP,TSC1,TSC2" Drug CID000013538 beta-cyanoalanine Stitch 1.45E-05 6.37E-01 3.54E-04 3.99E-03 11 23 "NFS1,CBS,KYAT1,CTH,PCYOX1,GGT7,MATN3,YY1AP1,CLSTN2,TK2,TST" Drug CID005288631 Im z Stitch 1.45E-05 6.37E-01 3.54E-04 3.99E-03 11 23 "BRAP,SEMA7A,CA4,TBPL1,ARHGAP32,ZMYND10,IGFBPL1,ZEB1,RGMB,SMUG1,RTN4" Drug 2678_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.48E-05 6.47E-01 3.59E-04 4.04E-03 40 177 "AMPD3,PPP4R4,DNAH17,ATP6V0A1,CFAP410,CREM,SIPA1L1,PDE4DIP,DGKG,HIPK3,FAM13A,MBNL2,VPS13B,FER,PRKAG2,PDLIM5,GALC,GLYR1,LILRA2,GRIK5,GSN,ATXN2L,IL6ST,SCAMP5,PDE4B,CCSER2,PMP22,MBOAT7,PRKACB,PTPRN2,GSTCD,HSPA4L,DNMBP,TRPS1,VGF,ZBTB38,PRDM10,KCNAB1,FZD3,FXR1" Drug 2462_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.48E-05 6.47E-01 3.59E-04 4.04E-03 40 177 "OSBPL1A,AK2,C1QTNF3,GAS7,EIF4G3,N4BP2L1,CFLAR,TPP1,CPS1,ARHGEF10,IPCEF1,HDAC4,ZNF804A,ANKRD46,FRY,KMT5B,SH3YL1,CAMKK2,IRAK3,ZNF862,NEK1,P2RX7,RETREG1,SLC25A23,PIGG,PTPRE,RAD51D,RBBP6,RPS6KA2,DGLUCY,SH3BP2,CEP68,FAM208A,KIAA0930,CBX5,TNS1,FLRT2,TRIM9,NAV3,MPPE1" Drug 3395_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.48E-05 6.47E-01 3.59E-04 4.04E-03 40 177 "NME5,ALCAM,MARK4,ST3GAL5,BAIAP3,CLGN,WHRN,PDE4DIP,ARMCX2,TMCC2,TSPAN5,FAM13A,AASS,RASGRP2,FYN,CYP46A1,KCNB1,NEK1,PCDH9,TMOD2,SERPINI1,PRPH,PTPRH,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,PKNOX2,ELOVL4,RGL1,STXBP1,ZEB1,HEY1,RUNDC3B,SSBP2,REEP1,SLC30A3,SLC17A7,ITM2C" Drug CID000016953 thioflavin T Stitch 1.50E-05 6.57E-01 3.64E-04 4.10E-03 34 141 "ACHE,APAF1,APC,APLP1,APOC1,APOC2,BCHE,DYNC1I1,ENO2,PPP1R1B,PPARGC1A,TCERG1,PACSIN2,SMAD1,KITLG,OGG1,ABCB1,FSD1,MAPK9,MAPK10,PTX3,QDPR,FBXW7,SALL1,ATXN7,FOXRED1,NLGN1,DDN,SYP,ZIC1,SLC30A3,PRTFDC1,NETO1,JPH3" Drug CID000005722 zaprinast Stitch 1.50E-05 6.57E-01 3.64E-04 4.10E-03 34 141 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,AGT,ABCD2,ARSE,PDE8B,ALDH7A1,RGS9,CALM1,KRIT1,LRBA,NUMBL,CHGB,ABCC5,EDN1,CALCRL,PDLIM5,PPARGC1A,GUCY1B1,NPR2,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,RYR3,SIRT1" Drug 4252_UP Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "PKP4,MARK4,KSR1,CACNA1I,LDB2,CNTFR,AKAP6,NCOR2,CSF1R,ARHGEF10,PDE4DIP,CNTNAP2,RIPOR2,DAPK3,SV2B,EDNRA,EIF4G2,NCALD,ETV1,NRN1,FGFR1,SYT17,NEU3,SRCAP,PCDH17,MCHR1,GRIK5,ELOVL5,IRF8,NPTX1,MAPK10,CNNM2,C1orf54,RGS4,RGS12,PREX2,BTBD7,SP4,PHF24,TK2,TNS1,LAT2,DPF3" Drug 4814_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "EPB41L5,CDC14B,ARHGDIG,ARHGEF2,CHN2,AKAP7,SNCAIP,CSF1R,RGS6,CTH,RIMS2,MFAP3L,RUSC2,C3orf18,FGF13,FGFR1,MALT1,TDRKH,STMN2,ATXN2L,VSIG4,NNAT,NPTX1,NTRK2,SNX10,PLCD1,PPP5C,MAPK7,ZSCAN32,OGDHL,SPP1,ZC3H13,ATP10B,THSD1,PLCB1,ANKRD12,EXOC7,KIAA1107,TBCEL,PCDHA5,TRIO,WIPF1,SLC30A3" Drug 3099_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ABHD6,MTUS1,BIN1,SEMA7A,ARSE,SLC4A4,BMP7,CFAP410,CBFA2T2,AKAP6,NCOR2,CRYM,CNTNAP2,DZIP3,EDIL3,RASGRP2,STX2,NCALD,DLC1,SIGLEC8,ALDH1L1,HNMT,MAP4,MGAT3,SCAMP5,ADAM22,MYT1,SEPT4,FSD1,CEP41,PRKAR1B,MASP1,TMEM255A,FAT4,RORB,TCP11L1,ASAP3,ABLIM3,SLC11A1,HECW1,XRCC4,MAP3K12,KCNAB1" Drug 2058_UP Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "MTUS1,NME5,ADGRF5,SOCS6,HOMER3,ARMC8,ABI3BP,PDE4DIP,PPP6R2,USP6NL,ING4,FER,ANKFY1,ERAP1,SRCAP,GLYR1,STON1,GPER1,CACFD1,FICD,IFI16,SHISAL1,KIFC3,SAMD9,PTPRE,SH3TC2,RGS4,SUGCT,AP1AR,TRA2B,ZFP30,KDM4B,SAMSN1,SS18,TBL1X,TCF4,DOCK9,CRTC1,ZNF34,HEY1,KAT6B,WIPF1,EMSY" Drug 4314_DN Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AK2,LGR5,SLC4A4,NRG2,CRMP1,ABCG1,AATK,VCAN,C2CD2L,TMCC2,DTNA,ING4,CDKL3,ETV1,FGF1,MSL3,GSTM5,GUCY1B1,ELOVL5,SCIN,IL6ST,INPP5B,AFF1,MMP16,TAGLN3,NDP,ZNF426,PRPH,TMEM104,WDR25,C1orf54,BEND5,DCUN1D2,GSTCD,ZNF415,DOP1A,DOK5,TCF4,TRIO,VIPR2,KCNAB1,KAT6A,DPF3" Drug 5759_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,ADRA1D,AP2A2,NME5,APOC1,CDC14B,ARNTL,STX16,CA8,B4GALT6,VCAN,ARHGEF4,RASSF2,MFAP3L,IRAK4,COQ7,EZH1,FGF13,GAD1,INPP5K,GNG4,PCLO,HAS2,NDP,PLCD1,GRAMD1C,TMEM231,FBXW7,FBXO11,DOK5,ARHGAP26,THSD1,SEPT8,COBL,KIAA0930,GPR161,LMF1,WIPF1,LAT2,XRCC4,TFIP11,MAP3K12,HPS4" Drug 1964_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ACTN1,NDRG2,ADAM23,SYNJ1,RUNX1T1,KRIT1,LRBA,FOXN3,TBC1D5,MAML1,GIT2,RCAN1,SUGP2,DENND4A,SEC23B,FAM49B,ARFIP1,GLUL,LILRA2,GRB10,KTN1,MAP4,MITF,OCRL,OPA1,CLIP1,ATXN2,SH3BP2,PEX26,CCDC88A,GLT8D1,ARHGAP26,RBM26,DIP2A,TACC1,TMPO,CHST5,UBTF,GORASP1,LAT2,CLDND1,ZNF142,URM1" Drug 7054_UP SB 202190; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ABHD6,AP2A2,AK2,ADGRF5,APC,SYNJ1,ST3GAL5,GYG2,CAMK2G,ARHGEF1,CBFA2T2,MAGI1,FAM189A2,ARHGEF4,PPP6R2,RUBCN,EDNRA,ZNF589,FGFR1,IQCG,OGA,B4GALNT1,AHDC1,MALT1,IL6ST,INPP5B,MAP4,MGAT3,NLE1,SLC25A23,PLXNB1,FAM184A,RGS12,SBF1,SYBU,ABLIM3,PEX26,KIF13A,MCF2L,EXOC7,ZKSCAN5,HPS4,SEMA3B" Drug 6229_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AK2,APAF1,GAS7,APOC1,PPFIA3,SEMA4G,SLC4A4,SYNJ2,MTMR2,LDLRAD4,CA12,CACNA1A,HOMER3,PDE4DIP,EGFR,ING4,FAM198B,OLFM1,FGFR1,TRAF3IP2,GFER,GLYR1,HTATSF1,MAP4K5,KHK,IPO5,LMO2,ZNF862,SAMD9,NKAIN1,SBF1,FBXO11,ABLIM3,LIMS2,PDZD2,SPTAN1,TTBK2,ARHGEF9,TAL1,WSCD1,PIK3R5,DNALI1,MPPE1" Drug 3374_UP Aminophylline [317-34-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADCY6,ADORA2A,SEMA6A,LGR5,DNAH17,CA4,HIP1R,PLEKHB1,COL9A3,CSF1,ARHGEF4,RIMS2,MBNL2,EGR3,AASS,ERBB2,DLC1,FGFR1,FHL1,GAD1,NEU3,ALDH1L1,RUNDC3A,GPER1,GPR37,GRIK5,LAMA2,MEF2C,MGAT3,AFF1,NECAB2,LRRN3,KLHDC8A,SATB1,CDK19,ATP10B,PCDHGA10,THRA,R3HDM1,TPM2,LAT2,SLC30A3,KCNAB1" Drug 7208_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ALCAM,BBOX1,BEGAIN,AMPH,ARRB1,KSR1,ST3GAL5,SCAPER,BAIAP3,CAMK2G,SEPT7,CHN2,AKAP7,CRY2,GIT2,ARMCX2,DLC1,FER,BAIAP2,OGA,GCNT2,TDRKH,JAK2,KCNQ3,MAPT,MSI1,NPR2,RETREG1,PRODH,PTPRE,C1orf54,RASGRF1,ZFHX4,SNCA,KDM4C,PHLDB1,PLCB1,TRIM2,PIK3R5,XRCC4,PLSCR4,ST7,PHTF2" Drug 2818_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,NDRG2,ALCAM,CA4,CACNA2D2,RCBTB2,FOXN3,AKAP7,ARHGEF10,ARHGEF4,PARD6A,DTNB,PLEKHA1,HSD17B14,ERCC2,DISC1,GPD2,LILRA2,GPER1,ADAMTS13,MAP4,NEFM,CLDN11,PLCD1,PLTP,LRP12,ZSCAN2,RPS6KA2,SBF1,STUM,EPN2,LHPP,PHLDB1,ARC,TBCEL,WSCD1,SZT2,DICER1,ZNF34,TK2,PLPPR2,KLC2,MPPE1" Drug 5740_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "SPARCL1,APBB2,GAS7,ADGRB2,BAIAP3,PLEKHB1,STOML1,RAB26,CNR1,RIPOR2,FBXL5,RGS17,RASGRP2,PTK2B,FLT1,TRMO,ZNF44,GATM,LYVE1,COPS8,GRIK5,ATXN2L,LSS,MGAT3,TAGLN3,NRCAM,CEP41,ZSCAN2,RGS4,EMID1,PPP4R3A,PKNOX2,SOX15,LHPP,SMG6,SYNE1,THRA,TLR4,PIK3R5,AMACR,LMF1,ZBTB14,ZNF711" Drug 3210_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "CDC42BPA,PPP4R4,PTCH2,N4BP2L1,AZGP1,BAIAP3,CA4,KALRN,MAGI1,CHN2,RAB33A,TPP1,BAG4,CRY2,SIPA1L1,CNTNAP2,ARHGEF4,SPOCK2,EDNRA,EGFR,DCTN2,TRAF3IP2,ERAP1,PRUNE2,TPPP,ATXN2L,C2orf72,INPP5B,MYCN,NOVA2,PLCD1,MBOAT7,SBF1,SCN2B,SH3GL3,ASAP3,SLA,SLC11A1,ATP10B,PHLDB1,ARC,TK2,SLC30A3" Drug 3360_UP Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "LTBP4,ST3GAL5,CACNA1I,BAIAP3,LDLRAD4,ARHGEF1,TPP1,CRYM,SPOCK2,MBNL2,EGR3,AASS,ZNF589,FGFR1,GPD2,TDRKH,INPP5B,KCNN1,AFF1,TAGLN3,NEFM,TMOD2,PPP1R1A,C1orf54,TRIM68,ASAP3,FNDC3A,BTBD7,CXXC4,COA1,SP4,ARHGAP26,RGL1,SYT5,OBSL1,TNS2,GPR161,TNS1,TRPM2,WIPF1,LAT2,DNALI1,SLC17A7" Drug 6363_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NME5,AMPD3,APC,LGR5,ARRB1,PDE8B,SLC4A4,CBFA2T2,SULT4A1,CNR1,CNTN1,FAM149A,AATK,CSF1R,CNTNAP2,ARHGAP24,DAPK3,EXOG,SNX29,EDN1,EDNRA,CORO2B,PDLIM5,KCNMB4,NXPH3,INPP5B,INSM1,MEF2C,SAMD14,STRN3,RELN,CNTLN,PTCH1,PTPRB,PTPRN2,UNC5B,PEG10,SYT5,TK2,CA14,UCHL1,UGT8,LAT2" Drug 7225_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NDRG2,AK2,APBB2,APOC1,PPP4R4,ARRB1,ST3GAL5,CNTN1,ARMC8,FAM149A,NRG2,AKAP12,CSF1,ARHGEF10,HIPK3,HSD17B14,VPS13B,RASL12,REEP2,BAIAP2,ERAP1,SIGLEC8,GPD2,GSN,TAGLN3,ZNF862,NEK1,RETREG1,LRP12,MINDY2,KHDRBS2,EMID1,ASAP3,PKNOX2,SPTAN1,ATP10B,PLCB1,WSCD1,FAM155A,ZNF74,GDPD5,UBE3B,PHTF2" Drug 7205_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ACTN1,NDRG2,FZD9,NME5,AK2,APBA2,CDK10,ARHGDIG,NRP2,CACNB4,CAMK2G,USP2,CLGN,B4GALT6,AKAP7,RCHY1,BAG4,NCOR2,RGS6,ST3GAL6,DLL3,OGA,GATM,RUNDC3A,PRUNE2,GRIK5,GRM8,ITPKB,LIG4,NF1,SLC25A23,PRPH,RGS12,GSTCD,PEX26,EPN2,PHLDB1,TRIM2,PCDHA5,FAM155A,ZNF711,ZNF24,SEMA3B" Drug 5533_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADD2,AMPH,BIN1,ANK2,GAS7,CDC14B,CNTN1,SH2B1,CSF1,C2CD2L,SNX29,OLFM1,LYVE1,POLL,GRB10,ATXN2L,VSIG4,HNMT,ICA1,MAN2A2,MBD1,MSR1,ZNF862,NF1,NFYA,NOVA2,NTRK2,ELOVL2,PTPRD,CPEB3,AMBRA1,ZKSCAN3,KIF13A,CRTC1,TK2,HIRA,SPHK2,FTSJ1,SLC30A3,EVI5,SEMA3B,ADAMTSL3,DPF3" Drug 3739_DN Foliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ALK,RIPK1,MYRF,CACNA1A,NRG2,SH2B1,AATK,CSNK1E,ARHGEF4,DAPK3,PARD6A,SPOCK3,PLXNC1,STX2,CDKL3,FGF1,CGREF1,RAB30,KCNMB4,GRIK5,GUCY1B1,KCNJ5,LMO2,MT1M,PCBP3,PIK3R1,MINDY2,GAL3ST4,TCP11L1,ASAP3,AMBRA1,ZNF415,IQSEC2,THSD1,SYN2,TBCEL,DOCK9,TIAM1,UBE2H,KLC2,TRIM9,NT5M,GAN" Drug 5331_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADCY6,AGT,AK2,C1QTNF3,SEMA6A,MARK4,CACNA1I,BAIAP3,ARHGEF1,ARHGEF2,CHN2,QKI,DZIP3,EZH1,FER,BAIAP2,IQCG,FYB1,ZNF276,GLYR1,MSL3,FERMT2,ATXN2L,ELOVL5,DHX35,MAP4,MAPT,LYRM9,NF1,NLE1,PLCD1,PRKAR1B,TMEM104,RGS12,PNMA8A,ZNF821,KDM4B,TK2,FAM155A,PLPPR2,MAP3K12,HPS4,MPPE1" Drug 3194_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NDRG2,PRX,PPP4R4,ARHGDIG,ATP2B2,ADAM23,AZGP1,CFAP410,KALRN,RUNX1T1,CD86,B4GALT6,RCHY1,CLIP3,RGS6,IPCEF1,SNPH,SHANK1,HIPK3,ING4,TLR7,OLFM1,AFF2,KHDRBS3,DLL3,SEPT9,RUNDC3A,GNAO1,KIFC3,MYT1,PLTP,PSD,TRIM68,RGS4,SLA,PKNOX2,LMO3,SYT5,TACR1,KIAA1107,CUX2,MKRN3,SEMA3B" Drug 2969_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NDRG2,CDC42BPA,APBB2,STX16,BCL7A,C5,CAPN3,SLC4A8,RCHY1,CSNK1E,VCAN,EXOG,MBNL2,RASGRP2,F5,KAT8,SEMA4D,RAB40B,LILRA2,IL6ST,IPO5,AFDN,PIK3R1,PLCD1,PLCL1,RET,SEMA6D,ST6GAL1,CCDC92,ANKRD6,DHX30,SLC11A1,ZHX3,DBNDD2,SPTAN1,TROVE2,EXOC7,TCF4,OBSL1,SLC44A1,TMPO,TNS1,FLRT2" Drug 5754_DN Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AP2A2,NME5,PPFIA3,SEMA4G,MARCH3,SLC4A4,CFLAR,KYAT1,SULT4A1,USP6NL,GIT2,CDON,DPH1,FAM13A,EIF4G2,DENND4A,FGF1,FGFR1,IQCG,CINP,FYN,GLI2,MUM1,LIFR,ADAM22,TAGLN3,NEK1,NF1,POLG,MAPK7,RIPOR1,SH3TC2,RPS6KA2,CLIP1,IFT122,SNCA,CAMTA2,EXOC7,TK2,CABIN1,TNS1,LMF1,PHTF2" Drug 2796_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "BIN1,APC,AQP6,SLC4A4,CFLAR,SLC16A4,RCBTB2,ASIC3,TAOK2,ARHGAP22,WHRN,NRG2,NECTIN3,DGKG,DBT,DNM1,DTNB,TNK2,AFF2,ADAM28,TDRKH,GRB10,GRIK5,RASSF8,HNMT,TJAP1,KCNN1,P2RY1,PLCD1,SLC25A23,CNTLN,PTCH1,SH3BP2,ST6GAL1,NLGN1,PREX2,ZC3H13,ST5,ARC,HIF3A,ZNF34,TK2,CABIN1" Drug 3171_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AP2A2,AGT,FAM135A,ANK2,KCNAB2,SPTBN4,ALDH7A1,SYNJ2,GYG2,CFAP410,HAP1,CLGN,CLIP3,AATK,IPCEF1,DOCK4,DTNA,PLXNC1,PDLIM5,GATM,GUCY1A1,HLF,SYNPO,JAK2,KCNN1,MMP17,MSR1,ZNF862,NOVA2,PLTP,NECAB2,PPP5C,PRODH,MASP1,TACR1,SZT2,DOCK9,R3HDM1,PDIA2,KCNK12,TFIP11,NT5M,DPF3" Drug 5801_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,ADRA1D,CDK10,ADAM23,MTMR3,BAIAP3,RUNX1T1,SYNGR3,FOXN3,PLAA,RAB26,SPOCK2,DTNA,EDIL3,AASS,ING4,SYT17,GFER,SHISAL1,KCNB1,KCNF1,LSS,MGAT3,NPTX1,ENPP2,GPR85,PPARA,LRRN3,PRKCB,ENOX1,OGDHL,TSNAXIP1,ZSWIM8,HECW1,RBM26,ZFPM2,CHST5,KCNE5,TUBB1,VSNL1,REEP1,ADAMTS9,SLC17A7" Drug 5619_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "MARK4,SCAPER,MTMR3,GYG2,CAMK2G,CBFA2T2,B4GALT6,PDE4DIP,RCAN1,DTNA,OPTN,TNK2,DENND4A,RRAGB,KAT8,FGF12,FGFR1,BAIAP2,ALDH1L1,CACFD1,INPP5B,MAP4,LYRM9,RETREG1,LRP12,WDR25,SBF1,SH3BP2,EPN2,MAPKBP1,KDM4B,KDM4C,SPART,CLSTN2,THSD1,PLCB1,EXOC7,DMXL2,KIAA0930,ZBTB14,ZNF45,SLC17A7,MARCH8" Drug 6146_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "CDC42BPA,PKP4,APC,NCOA1,ATP6V0A1,CFLAR,SCAPER,CFAP410,CAPN3,KRIT1,HINFP,SLITRK5,NR1D2,DTNA,ST3GAL6,INPP5K,USP19,AGBL5,ICA1,IL6ST,LSS,MAP4,MIA2,SLC11A2,PLCB2,STRN3,PRKAB2,ZCWPW1,ZNF493,RNASEL,ZNF821,SH3BP2,NUBPL,PPP4R3A,KDM4C,SS18,PARD3,ZKSCAN5,FLRT2,XRCC4,EMSY,KCNAB1,UBE3B" Drug 5527_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ALK,BEGAIN,BIN1,AMT,APC,SEMA4G,ARHGDIG,PLA2G4C,CDK13,SYNJ1,SLC16A4,CDR1,VCAN,SEC14L5,SPOCK2,MFAP3L,ECM2,EDIL3,SNX29,MBNL2,CDKL3,F5,TOX3,ADAMTS13,IPO5,MARK1,MBD1,P2RY1,TREM2,SERPINI1,CNNM2,ELOVL2,TCP11L1,SYBU,CXXC4,ZBTB43,PHLDB1,DICER1,TK2,HIRA,SLC30A3,EMSY,JPH3" Drug 7186_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADCY6,C1QTNF3,APC,SEMA4G,ATP2B2,CFLAR,CA12,SCARB1,MAGI1,AKAP7,PDE4DIP,FAM169A,RIMS2,DBN1,MFAP3L,RCAN1,DTNA,BAIAP2,SEMA4D,ANKFY1,TXNL4A,KCNMB4,CACFD1,RASSF8,LIG4,CNOT4,SLC11A2,PDE4A,PRPH,RXRA,PPP4R3A,PKNOX2,MAPKBP1,SPTAN1,PHLDB1,PLCB1,EXOC7,THRA,TMPO,PIK3R5,NPL,VIPR2,WRN" Drug 5910_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "BIN1,ZSCAN18,CAMK2B,SCARB1,CHRNA4,EPS15L1,TPP1,CABP1,AKAP5,ENTPD4,MFAP3L,TNK2,MRNIP,RGS17,VPS13B,FGF12,ALDH1L1,GFER,GNG4,SPACA9,GUCY1B1,MAN2A2,CNOT4,NPTX1,PCBP3,NTRK2,PDE4B,RASGRF1,ZMAT4,RASA3,FRMPD1,AMBRA1,PKNOX2,SNCA,ARC,ASTN2,SYT5,EXOC7,CHST8,GPR161,TRIO,TRO,ZNF74" Drug 6141_DN Meropenem [96036-03-2]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ABHD6,MTUS1,APAF1,ARRB1,SLC4A4,N4BP2L1,SLC25A14,ARHGAP33,FOXN3,SOCS6,RAB28,ZFYVE16,RUSC2,FCF1,FAM13A,SCML2,ST3GAL6,PCYOX1,ANKFY1,OGA,ERAP1,SEPT9,ALDH1L1,SRCAP,TXNL4A,GLYR1,JAK2,MAP4,ZNF862,NF1,SLC11A2,SETD4,OCRL,SH3BP2,AMBRA1,FAM214B,SNCA,TSPYL2,PDLIM2,PARD3,HIRA,XRCC4,NT5M" Drug 4446_DN 2-propylpentanoic acid; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADRA1D,BIN1,CDK10,MARCH3,ADAM23,SYNJ1,CBFA2T2,ARHGAP33,RAB28,NRXN3,PICK1,CSF1R,FEM1B,EIF4G2,ING4,STX2,FGFR1,PDLIM5,INPP5K,SCIN,KPNA5,MIA2,MN1,MT1M,PFKFB4,MINDY2,SAMD9,PTPRH,RGS4,MAP6D1,SBF1,ZNF821,SNCA,SPTB,SAMSN1,COBL,DNAH7,TNS1,UBTF,VGF,WIPF1,ZNF24,TFIP11" Drug 6824_UP Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,ADORA1,APLP1,RASL11B,ATP2A2,SCAPER,GYG2,CALB1,RCBTB2,SULT4A1,WHRN,CSF1,VCAN,PDE4DIP,DBT,RUSC2,FGF1,PDLIM5,GAD1,SIGLEC8,GPER1,GRIK5,ICA1,KCNN2,KIT,MX1,NTRK3,PDE4D,ZSCAN2,ZFHX4,ST6GAL1,CXXC4,SNCA,FAIM2,SPTB,MCF2L2,PHLDB1,TBCEL,RPGRIP1L,CRTC1,DICER1,FLRT2,WIPF1" Drug 4423_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "GAS7,APLP1,SLC2A11,MTMR3,LDLRAD4,CAMK2B,CBFA2T2,CNTN1,NECTIN3,CPS1,SEC14L5,RCAN1,HIPK3,DENND4A,FGFR1,FHL1,KHDRBS3,DISC1,SEPT9,ALDH1L1,RUNDC3A,GLYR1,IL6ST,ITPKB,KCNN1,KCNN2,NEK1,SLC25A23,LRP12,MAPK7,GRAMD1C,PEX26,PKNOX2,PLCB1,SZT2,TK2,R3HDM1,TRIO,FAM155A,SPHK2,EMSY,SLC17A7,GAN" Drug 6701_DN Florfenicol [73231-34-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "PDE8B,MARK4,KIF1A,CFAP410,FOXN3,LHX2,AKAP7,IQCK,ARHGEF10,CNTNAP2,SGSM2,CHRDL1,CELSR3,COQ7,SEPT9,MSL3,TDRKH,MMP16,GIT1,RETREG1,GRAMD1C,TMEM231,PID1,C1orf54,ZCWPW1,BEND5,KHDRBS2,FBXW7,TCP11L1,RXRA,FAM192A,SPATA7,THSD1,CEP68,KIAA1107,TCF4,THRA,TNS1,LMF1,WNT7A,ZNF142,SEMA3B,KCNAB1" Drug 2296_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADD2,ADORA2A,ALK,DOC2A,CDC42BPA,GAS7,APLP1,SEMA4G,PDE8B,CFLAR,HIP1R,CHN2,WHRN,CRY2,HDAC9,DTNB,MTSS1L,ERCC2,DLC1,FGF12,SHISAL1,ITGAM,KCNJ5,MID1,NEFM,MAPK7,RELN,ZNF493,RGS12,KCTD17,EMID1,MRAS,SLC2A5,PKNOX2,SLC9A5,KDM4B,HECW1,ARC,SYT5,TBCEL,FAM155A,MKRN3,SPHK2" Drug 5454_DN Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,ALCAM,PPFIA3,MARK4,SCAPER,MTMR2,QKI,HOMER3,CREM,DCAF8,RUSC2,EXOG,STX2,EZH1,FGF12,FHL1,DISC1,RAB30,MSL3,POLL,GRB10,ITPKB,KPNA5,MAP4,MATK,NF1,NFYA,CNOT4,STRN3,MINDY2,PRPH,TMEM231,BTBD7,PHLDB1,PLCB1,DNMBP,KIAA0930,TIAM1,KLC2,KCNK12,ZNF74,SPHK2,GDPD5" Drug 6065_DN Suxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NDRG2,NME5,APBA2,MARK4,ARHGEF7,SCAPER,CAMK2B,CBFA2T2,SCARB1,CNTN1,SIPA1L1,PDE4DIP,DTNA,MBNL2,C3orf18,VPS13B,PRELID3A,DISC1,INPP5K,GCNT2,JAK2,LMO2,TM6SF1,MID1,MMP16,NF1,PDE4A,LRP12,PRKAR1B,MAPK7,WDR25,SEMA6D,SLC6A8,BTBD7,SNCA,THSD1,TRIM2,TMEM121,TK2,ZNF711,ZNF45,EMSY,MPPE1" Drug 5465_DN Pivampicillin [33817-20-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ALCAM,APC,SLC4A4,SCAPER,MTMR3,CAMK2G,LRRFIP1,RAB28,AKAP7,ZNF337,RCAN1,E2F5,EDNRA,CNNM1,EPB41L2,SCML2,FHL1,NOP56,SEPT9,SRCAP,GPD2,SPACA9,ELOVL5,KHK,MAP4,TM6SF1,MITF,MPP2,MYO9A,PRODH,TMEM104,RAD51D,GTDC1,RXRA,ATXN2,RBM34,CDK19,SAMSN1,TTBK2,PHLDB1,EXOC7,THRA,CDK20" Drug 2258_DN Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,APOC1,PPP4R4,ATP6V0A1,BLM,MTMR3,GYG2,SPAG9,FOXN3,FAM189A2,CNTN1,EGFR,ZNF589,FGF12,FGFR1,FAM49B,SRCAP,AHDC1,SPIN1,GRIK5,IL6ST,INPP5B,MAP4,ZNF862,CNOT4,OGG1,PIK3R1,PPP2R2B,PPP5C,ZDHHC14,SEC14L1,ZNF821,ANKRD6,BTBD7,SNCA,ZBTB43,STX1A,PRRC2C,PCDHA6,TMEM121,AP4E1,NDRG4,KCNAB1" Drug 2631_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ADCY6,NME5,ALCAM,FAM131A,SEMA4G,MARK4,N4BP2L1,BAIAP3,CAMK2A,USP2,CHN2,TAOK2,NDST3,ABI3BP,MYEF2,RUSC2,RASL12,ZNF589,AMOTL2,TPK1,NSG1,GAD1,PCDH17,GNAL,RASSF8,KCNN2,ADAM22,ENPP2,PLTP,POLG,PPARA,RFX2,SH3BP2,PREX2,SLC11A1,ZHX3,ARHGAP26,SPTAN1,PARD3,TRIO,HIRA,FLRT2,MKRN3" Drug 4409_UP Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "APLP1,LGR5,SEMA4G,DNAH17,BAIAP3,HIP1R,RUNX1T1,TPP1,STOML1,CLTB,SULT4A1,AKAP5,MYRIP,CSF1,VCAN,RIMS2,SHANK1,TOM1,MBNL2,OLFM1,ANKFY1,GAD1,GRM2,AP4S1,KCNB1,KCNJ5,AFDN,NPY,NPTX2,PDE1C,PDE4B,ZMAT4,RPS6KA2,SEMA6D,ZNF821,RASA3,SH3GL3,ASAP3,CDK19,TROVE2,TCF4,DOCK9,TRPM2" Drug 4760_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "NDRG3,NDRG2,DOC2A,AMPD3,BIN1,MARK4,ALDH7A1,GYG2,CA4,RCBTB2,LHX2,PLAA,CNTNAP2,RIMS2,DBT,ARMCX2,MFAP3L,ING4,DLC1,ST3GAL6,KAT8,FGFR1,AFF2,PDLIM5,TRAF3IP2,IL6ST,LIG4,MEF2C,KITLG,MMP16,NFYA,NPTX1,STRN3,GRAMD1C,SAMD9,KCTD17,SGK1,DOP1A,TNS2,CHST8,TRIO,ZNF45,PHTF2" Drug 3763_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AMPH,BCAS1,PDE8B,ATP6V0A1,SCAPER,CACNA1I,CA8,KALRN,SYNGR3,SULT4A1,EDNRB,EPHB1,NCALD,FGF1,OLFM1,BAIAP2,ADAM28,GNAL,GRM2,SOX21,ICA1,KCNQ3,MGAT3,ADAM22,MYO7A,TREM2,PCDH9,CDK18,PTCH1,PTN,CCDC40,STK32B,ARHGEF40,BTBD7,DOK5,ATP10B,EXOC7,TNS1,TRO,VIPR2,EVI5,KCNAB1,NLRP3" Drug 4092_DN Fillalbin [4540-25-4]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AMH,CDK13,MARK4,CACNA1I,BAIAP3,ABCG2,HOMER3,AKAP5,CSF1,DZIP3,DAPK3,RUSC2,EDNRB,PLXNC1,ZNF549,ETV1,ST3GAL6,FGFR1,EFCAB2,SEPT9,GNAL,LIFR,MATN3,NF1,NNAT,P2RY1,PDE4D,NLE1,MINDY2,KHDRBS2,RGS12,TCP11L1,RPS20,SNCA,SUPT5H,MCF2L,FBXW11,TK2,R3HDM1,HIRA,OSBP2,VGF,PARP11" Drug 4722_UP Merbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,ALCAM,AMT,EPB41L5,PLA2G4C,CFLAR,BAIAP3,CAMK2G,RUNX1T1,ARHGEF1,CSF1,GREB1,SPOCK2,GIT2,C2CD2L,EDN1,TNK2,NCALD,FGFR1,OGA,GALC,ALDH1L1,GLYR1,TDRKH,ITGA7,KCNH2,KIF5A,AFDN,MMP16,MMP17,NPR2,NKAIN1,CCDC40,RGS12,KCNIP1,CNKSR2,LIMCH1,SMG6,OBSL1,TNS1,LAT2,ITM2C,JPH3" Drug 1505_UP Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "SEMA4G,SYNJ1,SCAPER,CACNA1I,CACNA1G,CA4,QKI,LY86,ABI3BP,NCOR1,OSBPL3,RIMS2,HDAC4,DAPK1,MFAP3L,DUSP9,EIF4G2,SPEG,ZNF589,FLNC,CGREF1,RUNDC3A,POLL,NXPH3,ADAM22,ZNF862,NNAT,NOVA2,CEP41,PRKCB,PRODH,CEP97,ZFHX4,CARF,RASA3,SYBU,TTBK2,GPR161,BEX4,RUNDC3B,WIPF1,KCNK12,XRCC4" Drug 3106_UP Chrysin [480-40-0]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "AP2A2,AMPD3,BIN1,PLA2G4C,MPDZ,BMP7,CACNA1I,LDLRAD4,CAMK2B,CDH2,CREM,SH2B1,DZIP3,GPRASP1,SNPH,TM9SF4,DNAJB6,ANKRD46,CDKL3,ZNF276,GRIK5,LSS,MYO6,FXYD7,NLE1,SMIM7,LRRN3,CEP41,BCAS3,RORB,NEK11,RPS20,SH3BGR,SH3GL3,PEX26,CXXC4,MYH15,SOX15,HEY1,CBX5,RPRM,LMF1,SLC17A7" Drug 3789_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "LTBP4,AMH,CDC14B,CDK13,ADGRB2,NRP2,MTMR3,CACNA1I,LDLRAD4,CH25H,SYNGR3,ELN,EZH1,FGFR3,ALDH1L1,CSDC2,GLYR1,PRUNE2,LILRA2,GRM2,GSTM5,IGF1,KCNB1,SMAD1,MMP16,NF1,NPTX1,P2RX7,CDK18,NECAB2,PRKAR1B,PTPRD,STUM,SH3BP2,SLA,SLC11A1,KIF13A,FAIM2,TACR1,SPHK2,ADAMTS9,SEMA3B,GJC2" Drug 5928_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-05 6.89E-01 3.71E-04 4.18E-03 43 196 "ASIC1,AMPH,BIN1,APC,GAS7,CDK13,SLC4A4,KIF1A,CACNA1I,BAIAP3,ARMC8,HDAC9,ETV1,ANKMY1,EFCAB2,GAD1,SEPT9,AHDC1,LPAR4,IFI16,SCIN,IL6ST,AFDN,MSR1,MYO7A,NEK1,NF1,CNOT4,PALM,FRMPD1,SLA,SNCA,LHPP,ZEB1,SLC44A1,BHLHB9,TLR4,TPM2,XRCC4,ZNF711,REEP1,SLC17A7,PCBP4" Drug CID000020382 tetradotoxin Stitch 1.60E-05 7.02E-01 3.78E-04 4.25E-03 78 428 "ASIC1,ACHE,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,PHF12,ATP1A1,ATP1A3,ATP1B3,BCHE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CALB1,CCK,P2RX6,ASIC3,CHRNA4,CNR1,COX4I1,BOC,DMPK,EDN1,EDN3,EDNRA,EDNRB,PTK2B,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,INPP5K,CRCP,POLL,KCNMB4,LPAR4,STMN2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GUCY1B1,KCND2,KCNK3,KCNN1,KCNN3,P2RY13,NPY,NPR2,OPRL1,P2RX7,P2RY1,PDCD2,ENPP2,GPSM2,PRKCB,EPDR1,PTCH1,S100B,SCN7A,SCN8A,SLC6A11,SST,SYN2,SYP,TACR1,AKTIP,VIPR2,P2RY12,ST8SIA2" Drug 4307_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.62E-05 7.09E-01 3.81E-04 4.29E-03 42 190 "MTUS1,CDC42BPA,PKP4,APOC1,ALDH7A1,SPAG9,SRSF11,ENTPD4,EXOG,FCF1,IRAK4,STX2,VPS26C,ZNF44,SPIN1,HTATSF1,FERMT2,AGFG1,IFI16,IL6ST,MAP4,MMP16,NFIX,CNOT4,STRN3,PTPRH,SLC25A36,KIRREL1,SEC14L1,CCDC88A,ZNF667,ZBTB43,TBL1X,TCF4,DICER1,CBX5,TMPO,R3HDM1,VIPR2,ZNF74,ZBTB38,KAT6A" Drug 2465_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.62E-05 7.09E-01 3.81E-04 4.29E-03 42 190 "NDRG2,APAF1,KCNAB2,APBB2,ADAM15,BACH1,CCNT1,PLAA,CLCN3,TPP1,QKI,VCAN,DTNA,HIPK3,FCF1,VPS26C,PTK2B,KAT8,ZNF589,FHL1,EFCAB2,CELF1,GALC,INPP5K,TJAP1,ITGAM,AFF1,NEK1,CLIP1,SLC2A5,CCDC88A,SLC11A1,TROVE2,SS18,JMJD6,ARHGEF9,DICER1,TMPO,TRPS1,FLRT2,LAT2,REEP1" Drug 331_UP trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.62E-05 7.09E-01 3.81E-04 4.29E-03 42 190 "ASIC1,ABHD6,NME5,MARK4,BMP7,RAB29,BAIAP3,CLGN,SLIT2,RAB28,WHRN,ARMCX2,DRP2,ENO2,SPEG,F5,PCYOX1,POMT1,FYN,CYP46A1,RUNDC3A,RAB40B,TDRKH,RNFT2,MXI1,CDK18,SERPINI1,CCSER2,PLCD1,ZNF821,SH3BGR,SH3GL3,ANKRD6,WDR47,FAM214B,PKNOX2,NMNAT2,RGL1,STXBP1,TRIM2,PLPPR2,SLC17A7" Drug 4998_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.62E-05 7.09E-01 3.81E-04 4.29E-03 42 190 "RGS20,MARK4,CLGN,ASIC3,CNN3,ARHGEF6,SNPH,MFAP3L,RCAN1,C3orf18,HSD17B14,VPS13B,FHL1,OGA,GFER,GLYR1,PRUNE2,PCLO,GSN,INPP5B,KCNJ5,KCNN1,KITLG,MID1,AFF1,P2RY13,LRRN3,ELOVL2,LIMS2,PKNOX2,SNCA,IZUMO4,ST5,CEP68,PLCB1,ARC,TNS1,TRIO,KCNK12,MAP3K12,SEMA3B,KCNAB1" Drug 2669_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.66E-05 7.27E-01 3.91E-04 4.40E-03 41 184 "ABHD6,MTUS1,APBB2,APC,ST3GAL5,SGCE,HIP1R,RAB26,CREM,PDE4DIP,DZIP3,USP6NL,DOCK4,GSDME,MAMLD1,TSPAN5,FAM13A,MBNL2,TLR7,PDLIM5,STON1,GSN,IFI16,ITGAM,MEF2C,PCDH9,SERPINI1,PMP22,PPARA,SATB1,ELOVL4,RGL1,STXBP1,MTCL1,PJA1,DNMBP,TRIM2,RPGRIP1L,TRPS1,MAP3K12,PHTF2" Drug 5580_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-05 7.58E-01 4.05E-04 4.56E-03 39 172 "NME5,APAF1,ST3GAL5,BAIAP3,USP2,CLGN,PDE4DIP,ARMCX2,JAKMIP2,FAM13A,MBNL2,PTK2B,FYN,CYP46A1,STON1,PCLO,NEK1,PCDH9,TMOD2,SERPINI1,LRP12,PRPH,RPS20,SH3BGR,SH3GL3,ASAP3,CPEB3,WDR47,CCDC88A,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,UBE2H,CLIP2,SLC30A3,SLC17A7" Drug 2435_DN Bisacodyl [603-50-9]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APOC1,MARK4,SLC4A4,LDLRAD4,CBFA2T2,SCARB1,FOXN3,ARMC8,CRY2,CSNK1E,PPP6R2,TBC1D5,MAML1,DBT,KIAA0753,SGSM2,RCAN1,DTNA,COQ7,RASGRP2,CD320,TRMO,SPIN1,LILRA2,VSIG4,LSS,CNOT4,POLG,CNTLN,PTK2,EMID1,SEC14L1,RASA3,SH3BP2,ZKSCAN3,IZUMO4,TROVE2,PDLIM2,TK2,SSBP2,MAP3K12,GDPD5,ACTR3B" Drug 1749_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADORA1,AMPD3,PDE8B,ADGRB2,CACNA1A,CALB2,CACNA2D2,CHN2,CNTFR,IQCK,CRYM,TMCC2,DPH1,CNNM1,TNK2,ELN,FCGRT,FLT1,ALDH1L1,GNAO1,CACFD1,KCNF1,LAMA2,MBP,GIT1,SAMD14,MYT1,DUSP26,PPARA,PTN,RNASE1,RXRA,ATXN2,LIMS2,SLC6A11,SPTB,SS18,PLCB1,SYN2,CRTC1,DNAH7,VGF,NPDC1" Drug 2526_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,BRAP,ARRB1,NUMB,ADAM15,CACNA1A,CAPN3,AKAP7,BAG4,KIAA0753,SGSM2,DTNA,CELSR3,RASGRP2,ST3GAL6,ARFIP1,SLC2A6,ICA1,MAP4,MIA2,ZNF862,MYT1,PDE4D,PTX3,TMEM231,RXRA,TRAPPC13,SBF1,GALNT10,PPP4R3A,ZKSCAN3,SNCA,UNC5B,DDN,JMJD6,ARHGEF9,PARD3,CDK20,PLPPR2,XRCC4,ZNF74,GDPD5,FIP1L1" Drug 5118_DN Deptropine citrate [2169-75-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADCY6,AP2A2,BIN1,MADD,SCAPER,KRIT1,SCARB1,SOCS6,CNTNAP2,SLITRK5,ARHGEF4,DCAF4,F8,ZNF589,BAIAP2,ANKFY1,DENND2A,INPP5K,COPS8,GPER1,PCLO,HAS2,HNMT,SHISAL1,INPP5B,MPP2,GIT1,SETD4,SUPT20H,WDR37,SMARCD3,ZBTB43,CEP68,TACC1,DNMBP,IQCE,TCF4,KIAA0930,PARD3,UBTF,UGT8,WNT7A,TRIM9" Drug 6673_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASIC1,ADD2,AMPD3,GAS7,SEMA4G,CFLAR,MTMR3,MYRF,SEPT7,B4GALT6,NRXN3,ARMC8,WHRN,CPS1,CREM,ABCG1,ARMCX2,OPTN,PLXNC1,MTSS1L,ZNF391,SEMA4D,TRMO,DLL3,FYB1,B4GALNT1,GNAL,GNG4,MMP16,MPP2,ZNF426,PPP5C,GRAMD1C,SCN8A,ASAP3,DZIP1,ANKRD6,SMG6,DOCK9,OBSL1,VGF,TFIP11,SEMA3B" Drug 2718_DN "Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APBB2,CFLAR,CLGN,QKI,CSNK1G3,SLITRK5,TBC1D5,RCAN1,DTNA,PLXNC1,RASGRP2,ZNF589,ANKFY1,INPP5K,LILRA2,ITGAM,KIF2A,SMAD1,NF1,SLC11A2,ENPP2,SLC25A23,STRN3,ZSCAN32,TMEM231,FBXW7,CLIP1,HSPA4L,SLC2A5,ELMO2,ZNF667,TROVE2,SS18,NXT2,STX1A,ARHGEF9,EXOC7,KIAA1107,SZT2,KAT6B,TRPS1,HSPBP1,CLDND1" Drug 5060_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ALK,AMH,APOC1,ATP1A3,KSR1,CACNA2D2,WHRN,MYRIP,PDE4DIP,DUSP9,EDN3,PTK2B,ERAP1,SYT17,GFER,PCDH17,GNG4,GRIK5,FAM107A,IL6R,MAPT,MATN3,MYCN,LRRN3,PRKAR1B,MAPK7,PTPRB,PTPRH,PID1,RASGRF1,FBXW7,TCP11L1,SLA,SLC2A5,ZC3H13,COBL,TRIM2,SLC44A1,TPM1,RPRM,VGF,WNT7A,ZNF225" Drug 2070_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "BIN1,CDC42BPA,PPFIA3,SCAPER,CLCN3,VCAN,CTH,ARHGAP32,SNPH,RUSC2,E2F5,TRMO,DENND2A,DIDO1,RNFT2,SLC2A6,IPO5,MAP4,NFYA,SLC11A2,CCSER2,LRP12,FA2H,MINDY2,MAPK7,BCAS3,GTDC1,HSPA4L,FAM214B,ZKSCAN3,CDK5RAP2,IFT122,LIMCH1,SEPT8,TTBK2,FBXW11,TRIM2,FRYL,HIRA,FAM155A,LMF1,XRCC4,RNF170" Drug 4730_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "RALGAPA1,ADORA1,BAIAP3,CACNA1A,KALRN,RUNX1T1,EPS15L1,MYRIP,NCOR2,ARHGEF10,TMCC2,EDN1,HIPK3,HEYL,EGR3,RASGRP2,MTSS1L,FYB1,NEU3,GPR162,PCLO,GSN,HLF,ICA1,TJAP1,NPY,MTRF1L,MAPK7,PTCH1,C1orf54,RASA3,SYBU,KDM4B,UNC5B,SYP,ADGRL3,TCF4,RPGRIP1L,UGT8,WIPF1,LAT2,SEMA3B,HRASLS" Drug 3744_UP Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ANK2,ZSCAN18,ADAM23,MPDZ,NRP2,FUBP1,SCAPER,C5,IL33,RUNX1T1,RIMS2,DTNB,RGS17,MTSS1L,IQCG,GNAO1,LPAR4,GPER1,GRM2,GRM8,ICA1,C2orf72,TJAP1,KCNB1,LAMA2,AFDN,MYT1,NOVA2,NPTX1,PDE4A,LRRN3,CNNM2,CARF,KCNIP1,SH3BP2,FAIM2,ARC,ASTN2,MCF2L,TBCEL,ZEB1,TNS1,FLRT2" Drug 6091_DN Nadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,ALCAM,BIN1,APBA2,KCNAB2,ARHGDIG,DNAH17,MARK4,SLC4A4,EIF4G3,ADAM23,TAOK2,VAX2,CNTN1,CSF1R,PDE4DIP,RIMS2,TMCC2,PLXNC1,SCML2,DISC1,ALDH1L1,MSL3,CNTRL,INPP1,INPP5B,MMP16,NF1,MAPK7,PRODH,TMEM104,SBF1,PREX2,BTBD7,SNCA,ZHX3,KDM4C,EXOC7,PCDHA5,SLC44A1,ZKSCAN5,VIPR2,EPM2A" Drug 6077_DN Hexestrol [84-16-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "BIN1,APBA2,APBB2,NCOA1,GYG2,PLEKHB1,VAX2,AKAP7,NECTIN3,CRY2,DAPK3,C2CD2L,VPS13B,EZH1,FAM198B,CINP,CGREF1,GHR,POLL,GPR37,HNMT,INPP5B,LMO2,LSS,KITLG,MMP16,GIT1,MSI1,PCDH9,PRKAR1B,PTN,ZSCAN32,GSTCD,SBF1,RBM34,KDM4C,ZBTB43,VPS13A,MTCL1,WBP2,ZKSCAN5,WIPF1,UBE3B" Drug 2902_DN Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AP2A2,ARNTL,CDK13,NUMB,CFLAR,HOMER3,ARHGEF10,PPP1R16B,ARHGAP32,TBC1D5,DTNA,ABCC5,FHL1,ERAP1,RAB40B,MUM1,IL6R,JAK2,MX1,OPA1,PIK3R1,SNRK,TMEM231,ROGDI,DGLUCY,MAPK12,ZFP30,SH3BP2,PPM1E,ARFGAP1,TSPYL2,SS18,NSFL1C,DNMBP,PDLIM2,ZEB1,TMPO,ZNF24,ZNF225,NT5M,CIAPIN1,FIP1L1,MARCH8" Drug 2554_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,AMT,PPFIA4,APBB2,SCAPER,SCARB1,ARHGAP33,AKAP7,SEC31B,SIPA1L1,ZNF337,CDON,CELSR3,ST3GAL6,OGA,ERAP1,SRCAP,LILRA2,SPACA9,NCKAP1L,LSS,MIA2,OGG1,CCSER2,PLEC,PLTP,PTCH1,CEP97,SBF1,SIRT2,ZKSCAN3,ZNF667,MYH15,IZUMO4,SPTAN1,RBM26,STX1A,CHST8,R3HDM1,TPM1,LMF1,MAP3K12,EVI5" Drug 2522_UP Napelline [5008-52-6]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APC,DDO,ALDH7A1,RGS11,SYNJ1,CACNA1I,B4GALT6,LHX2,EPS15L1,RAB33A,CSF1R,DZIP3,ZNF337,BRINP1,B3GAT3,MFAP3L,PLXNC1,DLC1,ZMYND10,AFF2,DENND2A,NEU3,ALDH1L1,LYVE1,GNAL,LILRA2,GPR37,KCNN1,TAGLN3,MYO7A,NTRK2,EPB41L4B,MARCH1,SCN8A,SEC14L1,ASAP3,NLGN1,SYT1,EXOC7,DOCK9,TRO,OSBP2,LMF1" Drug 4639_UP Felbinac [5728-52-9]; Up 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASPHD1,ALK,KCNAB2,PPP4R4,KRIT1,PICK1,FAM149A,GAL3ST1,ARHGEF10,PHF14,FAM131B,HS3ST2,CNNM1,EZH1,FYB1,SIGLEC8,GPR75,GNAL,STON1,ITPKA,MATN3,AFDN,KCTD17,TCP11L1,FAM102A,NLGN1,LIMCH1,ZHX3,ARHGAP26,NFASC,TROVE2,ARC,COBL,SYT5,WSCD1,SSBP2,TUBB1,VGF,VLDLR,WIPF1,KCNK12,SLC17A7,DPF3" Drug 3085_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,BIN1,FGD2,APAF1,APC,APOC1,PDE8B,SLC4A4,RUNX1T1,LARGE1,CDR1,RAB33A,ABCG1,CRYM,CSNK1E,SPOCK2,CELSR3,EPB41,EPHB1,PRELID3A,SIGLEC8,GFER,GNAO1,GNG4,MCHR1,PADI2,NXPH3,ELOVL5,SCIN,MGAT3,AFDN,PRPH,MASP1,CNNM2,BCAS3,ZDHHC14,ASAP3,ZSWIM8,IZUMO4,DDN,TBCEL,SLC17A7,KCNAB1" Drug 4223_DN Nystatine [1400-61-9]; Down 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "MTUS1,SEMA7A,APOC1,CFAP410,ENTPD4,SLITRK5,PHF14,MFAP3L,DYNC1I1,DTNA,TOM1,FCF1,PLXNC1,ZNF391,CDKL3,ETV1,RRAGB,FGF1,TRMO,ZNF44,GAD1,HNMT,SHISAL1,PACRG,MATN3,TM6SF1,CNOT4,CLDN11,PIK3R1,CNTLN,PTCH1,ZNF821,FBXO11,LIMCH1,KDM4C,ARHGAP26,CDK19,SAMSN1,VGF,WIPF1,XRCC4,ZNF225,PLSCR4" Drug 3316_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,APLP1,CDC14B,DNAH17,PTCH2,CFLAR,CAMK2B,CBFA2T2,EPS15L1,RAB33A,STOML1,SULT4A1,LY86,PICK1,CSF1,F5,ZNF589,FGF12,FGFR1,AGAP2,TRAF3IP2,ALDH1L1,ADAMTS13,ZNF862,PPARA,PPP2R2B,GRAMD1C,ELOVL2,PTPRD,CRTAC1,KIRREL1,ASAP3,ARHGAP26,ATP10B,SYT5,CABIN1,PIK3R5,TRIO,TRPM2,KCNK12,XRCC4,DNALI1,SLC17A7" Drug 5565_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADORA2A,ADRA1D,AMPD3,AMT,APOC1,CHRD,SCAPER,CAMK2B,CLDN10,WHRN,COL9A3,RASSF2,TMCC2,DMPK,DTNB,EDNRA,RASGRP2,AGAP2,LYVE1,STON1,GPER1,GPR37,KCNJ5,MSR1,PCDH9,RETREG1,PLCB2,LRP12,MAPK10,PTPRB,PTPRO,PTX3,ZMAT4,RGS4,SH3BP2,ZNF423,ATP10B,RGL1,TAL1,TRPM2,WIPF1,TRIM9,DPF3" Drug 3007_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "SEMA4G,SLC4A4,BMP7,CACNA1G,CA12,HIP1R,STOML1,PICK1,SLC4A8,SEC14L5,MFAP3L,KLHL3,EXOG,DMD,FHL1,CSPG5,GALC,GATM,SPACA9,ATXN2L,SCIN,IL6ST,KCNN1,KHK,MMP16,OXTR,PCSK5,CCSER2,PPP5C,BCAS3,GDPD2,CXXC4,SMARCD3,EXOC7,DNMBP,TAL1,CRTC1,HIF3A,SSBP2,UBE3A,FLRT2,VSNL1,SPHK2" Drug 5051_UP Roxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASPHD1,ASIC1,ADRA1D,AK2,OGT,APAF1,KCNAB2,ARHGDIG,MARK4,NRP2,ASIC3,RAB26,PHF14,ARHGEF4,RIPOR2,DTNB,COQ7,MTSS1L,FGFR1,EFCAB2,SYT17,GFER,MAP2,MYT1,PCDH9,PDE4D,GPR85,PPARA,MAPK10,ZSCAN32,PID1,RASGRF1,SH3BP2,FRMPD1,HKDC1,CNKSR2,PKNOX2,IZUMO4,SPP1,SPTB,PHLDB1,RPRM,VGF" Drug 3202_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASPHD1,AP2A2,BCAS1,ARRB2,MARK4,ATP2A2,ATP6V0A1,CFLAR,ST3GAL5,SCAPER,MTMR2,CAMK2G,FAM189A2,ARHGEF6,AKAP7,SH2B1,CRY2,PPP6R2,CYBB,EDNRA,FGFR1,BAIAP2,ZNF44,TRAF3IP2,STON1,LPAR4,NF1,NNAT,MINDY2,RELN,TMEM104,PTPRE,RGS12,KDM4B,TROVE2,TTBK2,TACC1,SMG6,DOCK9,PARD3,CABIN1,VIPR2,REEP1" Drug 7217_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APBA2,GAS7,PRX,CACNA1I,BAIAP3,CA4,CACNB4,CALB2,CDH2,TAOK2,MYRIP,EXOG,DPP6,RASGRP2,MTSS1L,DLC1,BAIAP2,FHL1,TPK1,GNAL,GNAO1,GPR37,PCLO,KCNF1,AFDN,OPRL1,PDE4D,DUSP26,PRKAR1B,PTN,GSTCD,PLPPR3,SYBU,SLA,SLC11A1,LIMCH1,KDM4B,R3HDM1,AMACR,TRPM2,SPHK2,DNALI1,PHTF2" Drug 3857_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADRA1D,AK2,ALCAM,AMH,GAS7,CDK10,MARK4,NUMB,GYG2,CFAP410,NECTIN3,AKAP12,CSF1,GREB1,RIMS2,FAM49B,CGREF1,ALDH1L1,GFER,GNG4,STON1,ADAM22,ZNF862,PRKAR1B,SNRK,ZSCAN2,ENOX1,ZDHHC14,TRIM68,GTDC1,SH3BP2,PREX2,SNCA,TSPYL2,VPS13A,KIAA1107,IQCE,BHLHB9,VIPR2,LAT2,KCNK12,MAP3K12,GDPD5" Drug 3357_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADORA1,NME5,AMT,GAS7,CDK13,CACNA1G,CAMK2B,HIP1R,RUNX1T1,CNN3,PICK1,SPOCK2,EDNRA,AASS,LRRC17,SPEG,OLFM1,FHL1,AFF2,KHDRBS3,LYVE1,TJAP1,INPP5B,KCNH2,MEF2C,AFDN,NFIX,PLTP,C19orf57,SAMD9,ENOX1,CARF,STK32B,SH3BP2,ASAP3,SLC11A1,SLC14A1,SMARCD3,DOK5,ARHGAP26,WSCD1,ITM2C,NLRP3" Drug 3247_DN Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "SRPX,DOC2A,GAS7,ADAM15,MPDZ,MAGI1,B4GALT6,RAB28,QKI,SIPA1L1,DAPK3,DBT,MED12,RCAN1,TOM1,FCF1,EGFR,HSD17B14,EZH1,BAIAP2,FHL1,OGA,DISC1,SPACA9,KITLG,MPP2,GIT1,CNOT4,NLE1,PRKAR1B,ELOVL2,RGS12,MAPK12,RASA3,ELMO2,KDM4C,LHPP,ANKRD12,EXOC7,CHST8,ZNF24,EMSY,EPM2A" Drug 6348_UP Iopanoic acid [96-83-3]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "MTUS1,AMT,SEMA7A,SEMA4G,PDE8B,DNAH17,KSR1,BMP7,ARHGEF1,CNR1,AKAP7,AKAP6,ENTPD4,NCOR2,AATK,CNTNAP2,TOM1,DUSP9,EDIL3,EGFR,LRRC17,ERAP1,SPACA9,IRF8,IL6ST,KCNB1,KCNJ5,KIF5A,GIT1,NELL2,NF1,NNAT,PPARA,SCN8A,FNDC3A,CEP68,TLR4,R3HDM1,SMUG1,TRIO,LAT2,KCNAB1,DPF3" Drug 5630_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADCY6,APAF1,SEMA4G,ARHGDIG,CFAP410,KALRN,USP2,LHX2,SULT4A1,AKAP6,AATK,CSF1,C2CD2L,DMPK,EDNRA,EPHB1,DISC1,GNAO1,SOX21,ATXN2L,KIF5A,NFIX,CNOT4,NOVA2,NTRK2,CDK18,PFKFB2,POU6F1,CEP41,GDPD2,SNRK,PTPRB,RGS12,CPEB3,SLC11A1,WSCD1,ZEB1,HIF3A,TRPM2,VIPR2,SPHK2,SLC30A3,KCNAB1" Drug 7244_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "RALGAPA1,MTUS1,NME5,CASK,MARK4,ALDH7A1,SYNJ2,CBFA2T2,CHN2,QKI,HOMER3,NRG2,EGFR,MRNIP,FYB1,SYT17,USP19,COPS8,MSL3,HLF,SYNPO,INPP5B,ITPKA,MIA2,MN1,LRP12,FA2H,MAPK7,PTPRE,TMEM231,KHDRBS2,ZFP30,SLC9A5,ZNF334,SPTAN1,SS18,ELOVL4,CEP68,SMG6,VIPR2,HPS4,PHTF2,DPF3" Drug 5915_UP rotenone; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,KCNAB2,MARK4,CHRD,SLC4A4,ADAM23,BACH1,CACNA2D1,CALB2,HIP1R,ARHGEF2,SEPT7,CLTB,MYRIP,NECTIN3,HS3ST2,PLXNC1,ING4,FLNC,GRIK5,TJAP1,MAN2A2,MYO7A,NNAT,CLDN11,PLCD1,MAPK10,RELN,RPS6KA2,MRAS,ZKSCAN3,SPP1,ATP10B,TBCEL,RIMBP2,TNS1,TRO,UBE3A,VGF,WIPF1,SLC17A7,KCNAB1,UBE3B" Drug 3293_UP Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,KIAA1324,BIN1,APC,CDK10,C5,CALB2,CCNT1,FOXN3,RAB28,HOMER3,PICK1,MFAP3L,DTNA,EGFR,EIF4G2,FAM198B,FHL1,SCARA3,AGAP2,TMEM8B,INPP1,KHK,ZNF862,NNAT,NPR2,PLTP,LRP12,MAPK7,SAMD9,ZMAT4,PDZRN3,TSNAXIP1,ARC,TRIO,FLRT2,VLDLR,XRCC4,SPHK2,REEP1,ZNF189,SLC30A3,ITM2C" Drug 2944_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,APC,SLC4A4,STX16,N4BP2L1,MTMR2,LDLRAD4,DCTN1,E2F5,HIPK3,RASGRP2,F5,FAM49B,SEPT9,GATM,LILRA2,PADI2,TJAP1,ITGAM,JAK2,KIF2A,LIG4,MAP4,GIT1,CCSER2,MINDY2,SNRK,ZSCAN32,PTPRN2,DHX30,TSNAXIP1,SPTB,STXBP1,TBCEL,TCF4,ZEB1,TLR4,PIK3R5,CDK20,TRPS1,FAM155A,EPM2A,NLRP3" Drug 6497_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "SEMA6A,APOC1,RGS20,KSR1,CALB2,DLGAP1,CHGB,TPP1,HOMER3,NCOR2,CNTNAP2,GREB1,MFAP3L,RCAN1,FER,FGF1,AGAP2,DLL3,PCDH17,GNAL,PRUNE2,GRM2,HAS2,MATK,MBD1,MYO7A,CNOT4,GPR85,SAMD9,PTCH1,RGS3,RGS4,ZFHX4,ASAP3,MYH15,TRIM2,DOCK9,DICER1,SLC44A1,SPHK2,SLC30A3,KCNAB1,JPH3" Drug 6622_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ACHE,ADD1,APAF1,APBB2,ADAM15,FUBP1,RUNX1T1,SOCS6,KIAA0753,DTNA,HIPK3,ZNF589,FGF1,FAM49B,ZNF276,GLYR1,KITLG,NPR2,CLDN11,PALM,RETREG1,NLE1,PPARA,PPP5C,CEP41,PRPH,CCDC40,RAD51D,RASGRF1,RNASE1,STUM,ASAP3,PKNOX2,HECW1,ZC3H13,TSPYL2,CEP68,PHLDB1,TBCEL,TCF4,ZFPM2,ICAM5,ZNF24" Drug 1438_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,C1QTNF1,CFLAR,MTMR3,OSBPL3,RUBCN,FEM1B,ING4,EPB41L2,FCGRT,FGFR1,PRKAG2,ATP2C1,GAA,SRCAP,RUNDC3A,GRIK5,BTN2A1,MUM1,AGBL5,KIF2A,AFF1,NACA,NELL2,NF1,RETREG1,PLCD1,ZNF426,PTPRN2,GAL3ST4,FAM102A,KBTBD4,ELMO2,TBL1X,TK2,TNS1,CHST5,TSN,CA14,VIPR2,XRCC4,MPPE1,ACTR3B" Drug 7277_UP Azapropazone [13539-59-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "LGR5,WASF1,HOMER3,NRG2,SLITRK5,FAM131B,ARMCX2,RUSC2,RGS17,RABEPK,ETV1,FGF13,BAIAP2,FLNC,TRMO,COPS8,MUM1,IL6ST,SCAMP5,MKLN1,PALM,PDE1C,PLCD1,ZNF426,FA2H,PRKAB2,MAPK7,PTPRN2,KHDRBS2,RGS4,SLC14A1,SPTAN1,ZBTB43,SPART,THSD1,ZEB1,PARD3,RUNDC3B,SSBP2,WNT7A,NDRG4,KCNAB1,PHTF2" Drug 5052_UP Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASIC1,ADD2,ADORA1,PRX,PDE8B,MARK4,CFLAR,ST3GAL5,SCAPER,CALB2,HAP1,ARHGAP22,WHRN,FAM131B,MAML1,JAKMIP2,EDN1,COQ7,ABCA8,DLC1,FGF12,FGFR1,DCTN2,GNAO1,ICA1,KIT,LMO2,GIT1,PFKFB2,GRAMD1C,PTN,PTPRH,CCDC40,RGS12,KCTD17,CNKSR2,SPTB,PHLDB1,COBL,TBCEL,R3HDM1,CHST5,WIPF1" Drug 2140_UP Seneciphylline [480-81-9]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,C1QTNF3,APAF1,CASK,ARHGDIG,ATP6V0A1,QKI,ABI3BP,CREM,CSNK1E,VCAN,SCML2,GALC,ADAM28,ZNF276,PADI2,ATXN2L,KCNJ5,KHK,MAP4,TM6SF1,TAGLN3,NNAT,PFKFB4,PTPRN2,RIPOR1,ZCWPW1,RGS12,RXRA,SALL1,SOX15,KDM4C,SPTAN1,CEP68,ARHGEF9,TBCEL,AP4E1,RUNDC3B,LMF1,VSNL1,KLC2,MAP3K12,FZD3" Drug 6744_DN Metergoline [17692-51-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "C1QTNF1,CDC14B,ARHGDIG,PDE8B,MARK4,ATP1A3,ADAM23,SYNJ1,CACNA1I,MYRF,B4GALT6,WHRN,CRMP1,ARHGEF10,CNTNAP2,GPRASP1,BRINP1,MTSS1L,ZNF549,TRAF3IP2,SEPT9,GLYR1,STON1,GRM8,TJAP1,SCIN,MGAT3,MYT1,NF1,KCTD15,PRKAR1B,KHDRBS2,ATXN7,FRMPD1,EPN2,BTBD7,TSNAXIP1,LHPP,DOCK9,TNS1,VGF,VIPR2,KCNAB1" Drug 2314_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AMPD3,SEMA7A,MARK4,SCAPER,BAIAP3,HAP1,TAOK2,RAB33A,QKI,CRMP1,CSF1,C3orf18,HSD17B14,ANKMY1,ZNF589,FGFR1,ERAP1,SEPT9,GLYR1,SPACA9,GSN,ATXN2L,DHX35,KCNN2,ZNF862,PCDH9,CDK18,GSTCD,CCDC25,EMID1,ZNF821,SH3BP2,BTBD7,IQSEC2,ZBTB43,PHLDB1,SYN2,PCDHA6,THRA,FLRT2,ZFP37,EVI5,HPS4" Drug 7052_UP 0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,AK2,APC,GYG2,HAP1,CAMK2G,MAGI1,WHRN,ZNF804A,HS3ST2,KAT8,IQCG,OGA,B4GALNT1,AHDC1,GPER1,NXPH3,ELOVL5,MAP4,MPP2,MYO7A,MYO9A,SLC11A2,NTRK2,SERPINI1,PLCD1,SLC25A23,PLXNB1,ZCWPW1,DCUN1D2,SBF1,CCDC92,PEX26,KIF13A,KDM4B,ZSWIM8,JMJD6,VPS13A,WSCD1,CRTC1,CABIN1,XRCC4,SEMA3B" Drug 3881_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADRA1D,C1QTNF1,AMH,APAF1,APBA2,KCNAB2,BACH1,ADGRB3,CACNA2D1,DCLK1,COL9A3,DTNA,EDNRA,FAM13A,NRN1,DLC1,FGFR3,PDLIM5,CAMKK2,CSPG5,SEPT9,PCDH17,GNAL,PRUNE2,PCLO,ADAMTS13,ICA1,TJAP1,NCF2,NFIX,PCBP3,KCNIP1,CLIP1,SH3GL3,ARHGEF40,CXXC4,KDM4B,TCF4,DOCK9,CRTC1,TRO,SLC30A3,SLC17A7" Drug 4757_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASIC1,ADORA2A,ALK,AMPH,CDC42BPA,ANK2,MARK4,NRP2,CDO1,RCHY1,CPS1,AATK,CSF1,VCAN,HIPK3,CORO2B,DLC1,FHL1,OGA,GPR162,GRM8,KCNH2,MMP17,MSR1,TAGLN3,MYCN,PFKFB2,PLCD1,PTCH1,ACSM5,C1orf54,SH3BP2,SH3GL3,NLGN1,SLC11A1,TSNAXIP1,SPP1,PEG10,ATP10B,WIPF1,ZFP37,SLC17A7,PHTF2" Drug 6792_DN Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AP2A2,SYNJ2,SRSF11,SLIT2,ARMC8,ENTPD4,NCOR1,LRIG1,ARHGEF10,GIT2,DBT,DPYSL2,IRAK4,ERBB2,FGFR1,ANKFY1,ATP2C1,ZNF44,SRCAP,AHDC1,TXNL4A,PADI2,INPP5B,MAPT,GIT1,SLC11A2,PCDH9,PLXNB1,TMEM231,ZCWPW1,GTDC1,ROBO1,CLIP1,KIF16B,NUBPL,PDZRN3,CDK19,CEP68,SYT1,ASTN2,OBSL1,KAT6B,NDRG4" Drug 3629_DN PNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "C1QTNF3,BIN1,ARHGDIG,PLA2G4C,NCOA1,CFLAR,SYNJ2,SLC25A14,MAGI1,B4GALT6,BAG4,NECTIN3,DZIP3,MFAP3L,PARD6A,DTNA,EDNRA,SUGP2,MRNIP,RRAGB,FECH,FGF13,FGFR3,OGA,MALT1,MSL3,GNG4,ICA1,KCNN2,KITLG,MBOAT7,ZDHHC14,RGS3,DOK5,KDM4C,THSD1,EXOC7,PCDHA5,TPM1,TRIO,ZKSCAN5,FLRT2,VIPR2" Drug 6745_UP Midecamycin [35457-80-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASPHD1,SEMA6A,BEGAIN,KCNAB2,GAS7,DDO,SLC4A4,PROM1,BMPR1B,BAIAP3,CFAP410,CA12,CD86,SYNGR3,NDST3,HAPLN1,SEC14L5,DAPK3,PLPPR4,SRPK3,LRRC17,NRN1,EFCAB2,RAB30,TOX3,MT1M,MX1,MYH3,LYRM9,NELL2,NTRK3,NECAB2,PTPRB,SLC2A5,SNCA,KIF13A,ZHX3,SP2,ATP10B,TPM2,WIPF1,SLC17A7,KCNAB1" Drug 5092_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "SEMA7A,LDLRAD4,VAX2,CABP1,COL9A3,CRY2,RIMS2,DTNA,SRPK3,DLC1,FYB1,ZNF44,SIGLEC8,LYVE1,STON1,CACFD1,GRM2,IRAK3,HLF,ICA1,KIF5A,KIT,MAPT,AFDN,MMP16,MYH3,NOVA1,PFKFB4,PRKCB,PTH1R,TMEM231,RFX2,RNASEL,SLC2A5,ZHX3,TAL1,TPM1,TRO,VIPR2,LAT2,KCNK12,ADAMTS9,KCNAB1" Drug 6344_UP Betazole hydrochloride; Up 200; 27uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "C1QTNF1,MADD,DNAH17,ATP6V0A1,KIF1A,CFLAR,ST3GAL5,CBS,ENTPD4,CNTNAP2,ARHGAP24,EDIL3,STX2,ANKMY1,ZNF589,TRMO,FYB1,DENND2A,ZNF276,GLYR1,MSL3,SCIN,INPP5B,NF1,CNOT4,PALM,RETREG1,ZCWPW1,NEK11,CNKSR2,ZNF334,KDM4C,LHPP,ATP10B,SSTR2,TAL1,KIAA1107,TK2,TUBB1,RPRM,REEP1,SLC17A7,KAT6A" Drug 6289_DN Ganciclovir [82410-32-0]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AK2,BIN1,PKP4,FAM131A,CDC14B,PUM1,TM9SF4,GIT2,DBN1,DBT,B3GAT3,PARD6A,SPOCK3,FEM1B,CINP,TXNL4A,MSL3,HTATSF1,FERMT2,DIDO1,BTN2A1,MAP4,MYO6,PCDH9,PDE1C,PIK3R1,PRPH,CNNM2,ELOVL2,SH3TC2,RPS6KA2,MAPK12,SUPT20H,TRA2B,SH3BGR,FAM102A,ABLIM3,ZKSCAN3,KDM4B,UNC5B,CBX5,PLPPR2,NAV3" Drug 2573_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "MTUS1,AMT,PPFIA4,APC,CDC14B,PDE8B,CAPN3,CHN2,TPP1,VCAN,SPOCK3,TNK2,RASGRP2,DLC1,ST3GAL6,KAT8,NEU3,ALDH1L1,POLL,CACFD1,ATXN2L,MID1,AFDN,KCTD15,PTCH1,PTN,CEP97,FRMPD1,FNDC3A,CNKSR2,LIMS2,IZUMO4,SPTAN1,DMXL2,CRTC1,CHST8,SLC44A1,TPM1,VIPR2,CLIP2,REEP1,EVI5,PCBP4" Drug 4121_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ALK,GAS7,CDC14B,ATP2B2,CFLAR,WHRN,PDE4DIP,DMPK,CDON,FYN,GFER,POLL,GNAL,LPAR4,ATXN2L,SHISAL1,ITGA7,KCNN1,MMP16,MYT1,CDK18,PLCD1,PPP1R1A,MAPK7,SNRK,KLHL11,RPS6KA2,EMID1,SCN8A,SH3BP2,SLC2A5,PKNOX2,SMARCD3,NMNAT2,ZBTB43,LMO3,JMJD6,TPM1,TPM2,TRO,SLC30A3,NT5M,JPH3" Drug 2559_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADRA1D,APC,NCOA1,HIP1R,RAB33A,TPP1,QKI,BAG4,CPS1,CREM,ZNF337,DBT,DTNA,PDLIM5,OGA,USP19,TXNL4A,COPS8,LILRA2,MAP4,MEF2C,MIA2,PLEC,PTK2,C1orf109,FAM184A,RET,RNASEL,PCMTD2,SH3BP2,FUZ,AMBRA1,DZIP1,BTBD7,ZNF667,TBL1X,SLC44A1,R3HDM1,LMF1,ZNF32,ZNF74,REEP1,MAP3K12" Drug 6663_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABR,ACTN1,GAS7,CBFA2T2,SYNGR3,PDE4DIP,TBC1D5,MAMLD1,TENM1,RASSF8,TJAP1,SCIN,LYRM9,NF1,CNOT4,NPR2,PLXNB1,MAPK7,CNNM2,PTX3,SH3TC2,FAT4,RPS6KA2,ZNF821,FUZ,AMBRA1,DZIP1,SLC14A1,LIMCH1,TMCC1,TROVE2,ELOVL4,JMJD6,TRIM2,SYNE1,SLC44A1,BHLHB9,TNS1,WIPF1,EMSY,NAV3,SMIM8,PHTF2" Drug 1747_DN Lobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "C1QTNF1,MAP4K3,APBA2,BTK,RUNX1T1,CD38,EPS15L1,CLTB,DBN1,MBNL2,SEC23B,ZNF44,NEU3,CRCP,PRRC2B,DIDO1,ELOVL5,IDH3A,KTN1,MAP4,NF1,CNOT4,KCTD15,TRHDE,MAPK3,CNNM2,CHD9,WDR37,KBTBD4,TSPYL2,TTBK2,AGTPBP1,DMXL2,TRPS1,VGF,VIPR2,LAT2,XRCC4,REEP1,ZNF184,MPPE1,UBE3B,AAAS" Drug 4622_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AGT,APC,CDK10,NRP2,KSR1,CHN2,TPP1,CLTB,AKAP7,HAPLN1,NCOR2,ARHGEF10,PDE4DIP,C2CD2L,SEMA3D,EIF4G2,ELN,EPHB1,FGFR1,AGAP2,AFF2,GPR75,ICA1,LSS,SMAD9,AFDN,GIT1,NF1,PFKFB2,PIK3R1,STRN3,TMEM231,MARCH1,RFX2,RGS12,TRAPPC13,FUZ,SLC2A5,CXXC4,TLR4,TUBB1,KCNK12,GAN" Drug 1962_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "GAS7,SLC4A4,BID,CA12,PTBP2,CAMK2B,ARHGEF2,CDH2,FOXN3,TAOK2,CDC42BPB,SPOCK2,SPATA2,ZBTB24,C2CD2L,DNM1,COQ7,ETV1,POLR1B,BAIAP2,CAMKK2,OGA,TRAF3IP2,ERAP1,GRIK5,MAN1B1,GIT1,N6AMT1,MAPK3,FAM192A,SH3BP2,FAM214B,SLC11A1,ELMO2,HECW1,SS18,SYNE2,IQCE,TBL1X,TRIM2,OBSL1,TRPS1,KLC2" Drug 2300_DN Mebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APBB2,APOC1,PPFIA3,NCOA1,CA4,TPP1,ARMC8,CRY2,PDE4DIP,DCAF8,KIAA0586,DBN1,DBT,PHF20L1,EPB41L2,DENND4A,GALC,USP19,COPS8,SPACA9,HSF2,ITPKB,KCNN2,MATK,TM6SF1,RIPOR1,SYBU,PPP4R3A,FAM214B,RCOR3,FNBP1,TROVE2,ELOVL4,SEPT8,PLCB1,EXOC7,IQCE,PCDHA6,METTL3,REEP1,GDPD5,HPS4,LAS1L" Drug 2665_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,MTUS1,FGD2,SEMA4G,PPP4R4,CACNB4,P2RX6,SYNGR3,CRY2,SIPA1L1,PDE4DIP,DCAF4,SPOCK2,RCAN1,HIPK3,MBNL2,EIF1,FHL1,PDLIM5,GALC,GATM,LILRA2,ATXN2L,IL6ST,KCNQ3,MAP4,MEF2C,MSR1,MX1,PFKFB2,PLCD1,PLEC,PPARA,PTPRH,RPS20,TMCC1,CAMTA2,DNMBP,CRTC1,CHST8,AP4E1,TRPS1,PHTF2" Drug 5009_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADCY6,NME5,ARRB1,SLC4A4,KYAT1,CBFA2T2,SCARB1,RAB28,STOML1,CSF1R,PDE4DIP,TBC1D5,HIPK3,EGFR,MRNIP,ZNF589,FHL1,SYT17,SRCAP,MALT1,GLYR1,RAB30,INPP5B,JAK2,KITLG,MMP16,NFYA,NTRK2,RETREG1,PLCD1,POLG,CEP97,CPEB3,FUZ,FNDC3A,FAM214B,RBM34,ZHX3,LHPP,CDK20,VAV1,VGF,SMIM8" Drug 3719_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "LTBP4,APAF1,CDK10,PRX,DNAH17,ATP2B2,BMP7,GYG2,KALRN,NCOR2,CSF1,DAPK1,MFAP3L,SV2B,DMD,ETV1,KAT8,AGAP2,MAP4K5,NXPH3,MEF2C,ADAM22,MSR1,MYT1,NNAT,CDK18,GPR173,NECAB2,PPP2R2B,CEP41,PRKAR1B,PRKCB,CSRNP3,FNDC3A,ZNF334,RPGRIP1L,HIF3A,TK2,R3HDM1,TNS1,CDK20,RPRM,LAT2" Drug 4507_UP Ampyrone [83-07-8]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AP2A2,APAF1,PPP4R4,ATP2B2,MTMR3,LDLRAD4,LHX2,RAB33A,ABCG2,HOMER3,CNTN1,WHRN,SEC14L5,CHRDL1,PDLIM5,B4GALNT1,ERAP1,ATXN2L,ICA1,TJAP1,ADAM22,NPY,NOVA2,NPR2,NTRK2,RETREG1,NLE1,PPP5C,KCNIP1,WDR37,KANSL3,ZNF334,ZHX3,ZSWIM8,SPTAN1,ATP10B,PLCB1,MCF2L,SMG6,TPM1,VIPR2,ZNF225,GAN" Drug 1635_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AP2A2,CDC42BPA,APBB2,MARK4,SLC4A4,CFAP410,B4GALT6,HOMER3,CREM,CSF1,CTH,DCAF8,GIT2,DPH1,CNNM1,EGR3,TMEM164,ZNF276,POLL,GNG4,DHX35,MGAT3,MIA2,NF1,PLXNB1,RELN,TMEM104,PTCH1,RET,ROBO1,CCDC25,RPS6KA2,SYBU,KDM4C,CLSTN2,TRIM2,PCDHA6,CHST8,VGF,SPHK2,MAP3K12,SEMA3B,PHTF2" Drug 5703_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASIC1,NDRG2,C1QTNF1,LTBP4,SYT13,SLC4A4,ADGRB1,SLC16A4,CHRNA4,FHL5,WHRN,GIT2,CDON,DTNA,EDNRA,HIPK3,APC2,NRN1,FHL1,SIGLEC8,GNG4,PRUNE2,PCLO,GRB10,GSN,ATXN2L,INPP5B,KCNH2,MBD1,MINDY2,ENOX1,ZNF493,TCP11L1,ZNF821,RASA3,PREX2,SLC2A5,PKNOX2,SPTB,TACC1,PCDHGB6,PCDHA5,SEMA3B" Drug 3473_DN Iopamidol [60166-93-0]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ABHD6,NDRG2,BIN1,CDC42BPA,APBB2,CDK13,CFAP410,IQCK,ABI3BP,CRY2,CSNK1E,MFAP3L,DTNA,ZNF589,B4GALNT1,DISC1,GCNT2,POLL,LPAR4,CACFD1,ATXN2L,HNMT,LSS,MBD1,GIT1,NEK1,MAPK3,ELOVL2,ZSCAN32,RIPOR1,AMBRA1,ABLIM3,MAPKBP1,RBM34,ASTN2,IQCE,TNS2,KAT6B,TPM1,CDK20,UBTF,MAP3K12,RNF170" Drug 2814_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "BCAS1,MARK4,ATP6V0A1,RIPK1,GYG2,B4GALT6,FAM189A2,CNTN1,FBXL5,DMPK,DTNA,IRAK4,ING4,EZH1,FGFR1,IQCG,CGREF1,TRAF3IP2,TXNL4A,POLL,GNG4,ATXN2L,HNMT,INPP5B,JAK2,MAP4,MIA2,NEK1,NTRK2,MINDY2,PTPRE,TMEM231,RGS3,COA1,LIMCH1,MAPKBP1,SIN3B,DMXL2,RPGRIP1L,CDK20,PLPPR2,EMSY,FIP1L1" Drug 5463_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AGT,BIN1,CDC42BPA,CDC14B,MARK4,BAIAP3,HAP1,ARHGAP33,CHRNA4,FAM149A,WHRN,COL9A3,CSF1R,MBNL2,LRRC17,MTSS1L,FGF13,BAIAP2,AGAP2,SRCAP,PTPRT,DHX35,INPP5B,LAMA2,MID1,GIT1,ADAM22,MYO7A,NPTX1,MTRF1L,PPARA,RGS4,ZFHX4,ZNF821,FRMPD1,NLGN1,SLC6A8,ELMO2,DOCK9,AP4E1,WIPF1,NT5M,GDPD5" Drug 6174_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ADORA1,MTUS1,APAF1,PDE8B,ATP2B2,PROM1,SYNJ2,CSF1,CSNK1E,PDE4DIP,RIMS2,SNX29,EDNRB,MRNIP,STX2,APC2,REEP2,OLFM1,FGFR1,ADAM28,PCLO,PADI2,IGF1,MID1,ADAM22,TAGLN3,NELL2,NRCAM,RETREG1,MINDY2,SEMA6D,SH3BP2,FAM102A,HECW1,CDK19,LHPP,TROVE2,TACR1,KIAA1107,SLC44A1,ZBTB38,SEMA3B,PLSCR4" Drug 3529_DN Lansoprazole [103577-45-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "AK2,BIN1,CDC42BPA,PDE8B,MARK4,CFLAR,B4GALT6,QKI,SULT4A1,ABI3BP,SH2B1,CRY2,DZIP3,RUSC2,DTNA,EDNRA,MBNL2,IRAK4,FLNC,TRAF3IP2,DISC1,CNTRL,GRIK5,HNMT,INPP5B,JAK2,TM6SF1,MID1,GIT1,LYRM9,NNAT,NPR2,PALM,PLXNB1,CCDC25,SEMA6D,SIRT2,CHST8,ZNF34,PARD3,CDK20,SPHK2,RNF170" Drug 5919_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "N4BP2L1,KIF1A,NRP2,CAMK2G,LARGE1,EPS15L1,STOML1,PDE4DIP,PHF14,GIT2,DTNB,TOM1,NCALD,EZH1,KAT8,ZNF589,AFF2,DIDO1,SYNPO,KCNB1,KCNQ3,MAP2,ADAM22,NF1,NFYA,OXTR,CDK18,PDE4B,PDE4D,CNNM2,ZSCAN2,HSPA4L,SNCA,RBM34,PDZD2,FNBP1,HECW1,TSPYL2,BHLHB9,TRIO,RUNDC3B,FLRT2,GAN" Drug 6694_DN Loxapine succinate [27833-64-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASIC1,SHROOM2,PDE8B,MYRF,KRIT1,ABCG2,ARHGAP24,ARMCX2,RUSC2,SGSM2,EDIL3,HSD17B14,ETV1,PDLIM5,FYN,INPP5K,GPER1,GPR37,GUCY1B1,MEF2C,MMP16,NDP,PDE4B,PDPK1,RETREG1,GRAMD1C,PTN,PTPRN2,FAM184A,BEND5,GAL3ST4,KDM4D,MYH15,TCF4,TRIM2,DOCK9,DNAH7,GPR161,TK2,XRCC4,TRIM9,KCNAB1,MPPE1" Drug 2376_DN Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,ALK,ANK2,APC,CDK10,ARNTL,NCOA1,N4BP2L1,CCNT1,EPS15L1,IQCK,CST3,FBXL5,KIAA0753,COQ7,RASGRP2,ANKMY1,FGFR1,OGA,SEPT9,ALDH1L1,COPS8,MSL3,JAK2,LIG4,MAP4,GIT1,CNOT4,P2RX7,PIK3R1,CEP97,RET,TCP11L1,ARFGAP1,ZKSCAN3,ZBTB43,SEPT8,NSD1,TLR4,PIK3R5,ZNF74,ST7,NLRP3" Drug 1507_DN Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "GAS7,FAM131A,PPFIA3,CDK10,ARHGDIG,SLC4A4,SYNJ2,CAMK2G,QKI,DCAF8,KIAA0586,DAPK3,GIT2,EGFR,IRAK4,ANKMY1,EZH1,FAM49B,ATP2C1,RAB30,GNG4,DIDO1,RNFT2,INPP5B,MAP4,MBNL1,PIK3R1,PLEC,PLXNB1,TMEM104,RIPOR1,TCP11L1,PPP4R3A,SPTAN1,CLSTN2,ASTN2,TNS2,CRTC1,AP4E1,METTL3,MAP3K12,EPM2A,ST7" Drug 5638_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ALK,SLC4A4,KSR1,CCK,AKAP5,RASSF2,SPOCK2,HEPH,DMPK,ING4,ERCC2,FGF13,FGFR1,FLT1,GABRG2,ADAM28,SPACA9,ADAMTS13,GRIK5,KCNN1,KIT,CDK18,PDE4D,PFKFB2,LRRN3,RELN,SLA,FAM214B,KANSL3,OGDHL,KIF13A,ATP10B,SYN2,TACR1,ADGRL3,TRIM2,HIF3A,DNAH7,HEY1,UBE3A,UCHL1,WIPF1,KCNAB1" Drug 4142_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "NDRG2,ADORA1,LTBP4,APOC1,MARK4,CALB1,RUNX1T1,CRMP1,ARHGEF10,VCAN,RASSF2,SPOCK3,HS3ST2,ING4,PIPOX,GAD1,ERAP1,DISC1,GPD2,GRB10,DHX35,IL6ST,MAP4,MPP2,ADAM22,TAGLN3,NELL2,NNAT,PRKAB2,ZMAT4,RPS6KA2,SNAP25,ZHX3,IQSEC2,RBM26,THSD1,PRRC2C,EXOC7,TBCEL,SMG6,WSCD1,TNS2,TNS1" Drug 3686_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "APC,RASL11B,EIF4G3,CFLAR,SYNJ2,SCAPER,CFAP410,SYNGR3,ARHGEF2,LARGE1,PLEKHB1,TAOK2,PICK1,IRAK4,ANKMY1,FGFR1,KCNJ5,KHK,MAPT,PIK3R1,GRAMD1C,CNNM2,CNTLN,RGS4,NEK11,TCP11L1,ZNF821,ZFP30,ASAP3,DZIP1,ZNF667,ZNF415,IQSEC2,CDK19,LHPP,TROVE2,SS18,TPM2,RPRM,LMF1,WIPF1,XRCC4,SH3GLB2" Drug 825_DN rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.79E-05 7.86E-01 4.05E-04 4.56E-03 43 197 "ASPHD1,CLK4,C5,TAOK2,LHX2,RAB28,HOMER3,AKAP12,LYPD1,PARD6A,TNK2,COQ7,DLC1,KAT8,POLR1B,FGFR3,FHL1,ANKFY1,NOP56,EFCAB2,PRRC2B,DHX35,PLEC,RETREG2,PPP3CC,APTX,PTPN13,TCP11L1,TRAPPC13,CHD9,WDR37,SLC6A8,ITPRID2,ELOVL4,DIP2A,NSFL1C,JMJD6,KAT6B,TPM1,ZKSCAN5,XRCC4,TFIP11,SEMA3B" Drug ctd:C502851 quinocetone CTD 1.82E-05 7.96E-01 4.10E-04 4.62E-03 51 248 "GALNT13,TXNDC16,BIN1,DPP10,SEMA7A,ARHGDIA,ASPA,FUBP1,CA4,CACNA2D1,CALB1,CCK,DCLK1,CFL2,ABCG1,VCAN,CDON,ECM2,EDNRA,ENO2,ADGRV1,ST6GALNAC3,MEGF10,PCLO,GRM8,HMGCR,INSM1,LAMA2,STMN1,LSS,AQP11,MATN3,NDP,NFE2L2,SDK2,RELN,ENOX1,LRRK2,RYR3,SCN2B,RASA3,FHOD3,PDZD2,SPP1,ZNF423,ARHGAP26,NFASC,STAC2,SULF2,ADGRL3,WNK2" Drug ctd:D000431 Ethanol CTD 1.82E-05 7.96E-01 4.10E-04 4.62E-03 237 1620 "ACADM,ACHE,AS3MT,ADCY5,ADCY6,ADCY8,TMCC3,ADORA1,ADORA2A,ADRB2,AGT,AMPD3,AMPH,BIN1,PPFIA4,APAF1,BCAS1,ARHGDIA,ARRB1,ARRB2,ASGR1,RASL11B,ATP1B3,ATP2B2,ALDH7A1,AZGP1,MPDZ,CFLAR,BMP7,IL33,CA4,CA8,CACNA2D1,CALB1,CALM1,CAMK2A,CAMK2B,CAMK2G,RHBDL1,CBLN1,CBS,KYAT1,CCK,RGN,MTMR7,P2RX6,SCARB1,CDC25B,NRXN3,ABCG2,RAB26,CNN3,CNR1,SLC4A8,GAL3ST1,COX4I1,ZNF521,CPS1,CREM,SH2B1,ABCG1,CRYM,CS,GALNT9,PDE4DIP,ERC2,CTH,CYBB,HDAC4,DAPK3,DBN1,FAM107B,GRIN3A,MED12,CDON,SLC25A18,DTNA,SNX29,EDN1,EDNRB,EEF1D,EGFR,EGR3,HSD17B14,MFSD10,RASGRP2,GPHN,NCALD,NRN1,CLVS1,TUBA1B,PTK2B,TUBB3,TAOK3,RACK1,FCGRT,FDFT1,PPP1R1B,FGF1,ATP5PD,FOXO3,FLNC,FLT1,ZNF605,FYN,GABRA3,GABRB3,GABRG2,TRAF3IP2,GAD1,ALDH1L1,GCNT2,CSDC2,GHR,PPARGC1A,DHRS4,GLUL,GNAL,GNAO1,GPD1,GPD2,GRIA2,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM8,FAM107A,SLC2A6,NXPH3,PACSIN2,ELOVL5,HMGCR,HSF2,HSPA1L,SMAP1,IDH3A,SOWAHA,IGF1,IL6R,IL12A,KCNH2,KIFC3,L1CAM,LAMP2,LSS,MAP2,MAT2A,MATN3,MBP,CHIC1,MYH3,FXYD7,NCF2,NEFH,NFE2L2,NFIX,NME4,NPY,SLC11A2,NRCAM,OGG1,PDE4A,PDE4B,PDE4D,ENPP2,PFKFB4,PIK3R1,PLCD1,PLCL1,PMP22,PSAT1,POLR2F,PPARA,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK9,PTCH1,ELOVL2,STK32A,CASTOR1,PTPRO,NKAIN1,RAD17,RET,PCMTD2,RXRA,STX1B,S100B,SAFB,MAPK12,SCP2,SGK1,WDR37,ABLIM3,SIRT2,TET1,OGDHL,SNAP25,SNCA,KDM3A,SPP1,ZC3H13,DDN,LHPP,SSTR1,SEPT8,PHLDB1,STX1A,STXBP1,NSFL1C,DNAJC9,ARC,SYP,TAF6,PDLIM2,AGTPBP1,SYNE1,SIRT1,TLR4,CDK20,PRR18,UCHL1,CCDC136,VLDLR,RBFOX3,ZIC1,DPYSL5,SLC30A3,TUBA1A,SLC17A7,FZD3,GJC2" Drug 6839_DN Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "RALGAPA1,AK2,CFLAR,FOXN3,PLEKHB1,VAX2,ABCG1,FAM169A,CTH,ARHGEF4,RIMS2,DCTN1,PHF20L1,KAT8,FECH,SEMA4D,TXNL4A,ATXN2L,MEIS1,ADAM22,NF1,SMOX,PLXNB1,MINDY2,PTPN13,RBBP6,RGS12,SEC14L1,NUBPL,EPN2,BTBD7,TMCC1,KDM4C,POGZ,ITPRID2,THSD1,PLCB1,TRIM2,CHST8,GDPD5,MPPE1,MARCH8" Drug 6724_DN Digoxin [20830-75-5]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "ASIC1,APBB2,SHROOM2,CDC14B,RGS20,SYNJ2,LRRFIP1,SMARCAL1,APPL1,DCAF4,SNPH,ZBTB24,RHOBTB1,SACS,FAM49B,CGREF1,ZNF44,GPER1,GUCY1B1,ZNF862,PDCD2,PTPRE,PID1,SH3TC2,ZC3H14,MAP6D1,SUPT20H,FAM214B,ZNF667,MYH15,ZNF415,SPATA7,GLT8D1,CEP68,ARHGEF9,FAM208A,GPR161,TK2,CABIN1,METTL3,SMUG1,TIGD6" Drug 3448_UP Dienestrol [84-17-3]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "NME5,AK2,CDC42BPA,CDK13,MARK4,RASL11B,MTMR3,CACNB4,CACNA2D2,VAX2,CNNM1,EGFR,EGR3,LRRC17,DLC1,FGF12,BAIAP2,DISC1,NXPH3,TJAP1,TM6SF1,MITF,NNAT,SMOX,ELOVL2,ZDHHC14,ZFHX4,SUPT20H,RASA3,SGK1,SYBU,PREX2,EPN2,BTBD7,OGDHL,KDM4B,ARHGAP26,SPTAN1,ARC,PCDHA5,LAT2,SEMA3B" Drug 497_UP 2-propylpentanoic acid; Up 200; 1000uM; ssMCF7; HG-U133A Broad Institute CMAP Up 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "ABHD6,NDRG2,LTBP4,MARK4,ADGRB2,MPDZ,SYNJ1,SGCE,RAB29,BAIAP3,CAMK2A,LHX2,RAB28,ARHGEF10,C2CD2L,RGS17,ENO2,EPHB1,STX2,FHL1,NSG1,FYN,B4GALNT1,CYP46A1,KHK,MAPT,PLCD1,SUSD4,RGS3,PPM1E,ASAP3,FAM214B,SLC9A5,SNAP25,NMNAT2,TSPYL2,SPART,EXOC7,WSCD1,REEP1,MAP3K12,SLC17A7" Drug 489_UP radicicol; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "ASIC1,C1QTNF1,LTBP4,OGT,ANK2,ATP6V0A1,MTMR2,SGCE,HAP1,TAOK2,PLAA,AKAP7,CREM,ENTPD4,CRYM,LRIG1,DBT,STX2,NCALD,CAMKK2,STAU2,OGA,GABRG2,GPR37,FAM107A,RNFT2,KCNJ5,L1CAM,STMN1,MATK,NELL2,NTRK3,PLXNB1,POLG,PTCH1,HSPA4L,CDK5RAP2,TSPYL2,CLASP2,OBSL1,TNS1,FXR1" Drug 4168_DN Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "C1QTNF3,EP400,BACH1,SOCS6,QKI,PREPL,CRY2,FAM169A,DZIP3,GPRASP1,ZFYVE16,ZNF337,DBT,VPS13B,EZH1,PRKAG2,ANKFY1,GLYR1,PCLO,AFF1,CNOT4,CCSER2,RETREG1,POLG,VPS13C,RIPOR1,CLIP1,PEX26,FNBP1,ZHX3,CDK19,TROVE2,SYNE2,PLCB1,TACC1,ANKRD12,ZNF106,CBX5,TRPS1,VGF,VLDLR,ST7" Drug 6024_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "RALGAPA1,ALCAM,APBB2,MARCH3,CFLAR,ARHGEF2,SEPT7,TAOK2,SLIT2,RCHY1,CSF1,GPRASP1,ZNF337,DAPK3,DTNA,HIPK3,CDKL3,SCML2,ZNF589,GLYR1,GNG4,SLC2A6,KCNN2,IPO5,LIG4,MIA2,MMP16,ADAM22,PPP3CC,PRKAR1B,CEP97,TCP11L1,ZNF821,SUPT20H,ABLIM3,PLCB1,EXOC7,IQCE,PCDHA5,FRYL,VGF,GDPD5" Drug 4647_DN Butylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "ADCY6,APOC1,ARRB2,ATP2A2,SYNJ2,SPAG9,TAOK2,TPP1,QKI,PDE4DIP,CNTNAP2,ARHGEF4,DCAF4,GPRASP1,DBT,KIAA0753,FEM1B,EGFR,ANKMY1,FGFR1,ANKFY1,PRRC2B,GPD2,LIG4,NDP,NFYA,PLEC,TMEM231,TRAPPC13,SAFB,ZKSCAN3,SMARCA4,ARHGEF9,TCF4,TRIM2,TK2,CABIN1,TRIO,SSBP2,HIRA,UBTF,XRCC4" Drug 4190_UP Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.85E-05 8.10E-01 4.15E-04 4.68E-03 42 191 "RALGAPA1,NDRG2,SEMA6A,APC,KSR1,CARS,HIP1R,SCARB1,ARHGEF2,LARGE1,TPP1,ABCG2,WHRN,AKAP5,PDE4DIP,CNTNAP2,EDN3,ZNF589,B4GALNT1,SYT17,GLI2,GNAL,GNAO1,AP4S1,KIT,AFDN,NF1,SERPINI1,PPARA,PTPRG,C1orf54,RGS4,KCNIP1,FAM102A,NFASC,SYT5,PCDHA5,HEY1,TRO,FLRT2,VSNL1,KCNAB1" Drug CID000002207 2-amino-4-phosphonobutyric acid Stitch 1.89E-05 8.29E-01 4.24E-04 4.78E-03 25 91 "ADCY5,ADCY6,ADCY8,ADORA1,BCS1L,WASF1,CACNA1A,CACNA1B,CACNA2D1,CARS,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,MAP4,GPSM2,SPP1,SYN1,SYN2,SYT1,TSN,SLC30A3" Drug 6551_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.95E-05 8.54E-01 4.37E-04 4.92E-03 40 179 "ADRB2,NME5,BMP7,ST3GAL5,SCAPER,BAIAP3,CLGN,WHRN,PDE4DIP,DZIP3,ARMCX2,STX2,CDKL3,ACSL4,BAIAP2,FYN,INPP5K,CYP46A1,STON1,PCDH9,SERPINI1,GRAMD1C,PRPH,SH3BGR,SH3GL3,WDR47,PKNOX2,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,TACC1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,SLC17A7,ITM2C" Drug 5336_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.95E-05 8.54E-01 4.37E-04 4.92E-03 40 179 "ABHD6,NME5,ALCAM,APLP1,BMP7,ST3GAL5,CLGN,AKAP12,PDE4DIP,ARMCX2,TMCC2,TSPAN5,MBNL2,FHL1,FYN,CYP46A1,STON1,MITF,MXI1,NEK1,SERPINI1,GRAMD1C,PRPH,PTCH1,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,EVI5,GDPD5,SLC17A7,ITM2C" Drug 1112_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.95E-05 8.54E-01 4.37E-04 4.92E-03 40 179 "ABHD6,ARNTL,BMP7,ST3GAL5,RAB29,CBFA2T2,AKAP12,GIT2,TSPAN5,OPTN,MBNL2,STX2,EXTL2,TAOK3,FYN,RAB40B,RNFT2,PADI2,MXI1,NEK1,FA2H,PKIA,PRPH,SEC14L1,SH3BGR,SH3GL3,PPM1E,WDR47,ELMO2,KDM4B,SPTAN1,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,SSBP2,UBE2H" Drug 4248_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.95E-05 8.54E-01 4.37E-04 4.92E-03 40 179 "NME5,APAF1,MARK4,IL33,HAP1,RUNX1T1,CNTFR,CREM,SLITRK5,PHF14,CTH,RIMS2,RIPOR2,MAML1,DGKG,PITPNC1,DTNA,EDNRA,HIPK3,ZNF391,NRN1,ABCA8,PTK2B,TRMO,NEU3,IL6ST,NF1,NNAT,PDE4B,PDE4D,SMOX,PRODH,RGS3,KCNIP1,CSRNP3,ZNF334,ZC3H13,TBL1X,ZFPM2,TNS1" Drug 5308_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.99E-05 8.72E-01 4.37E-04 4.92E-03 39 173 "NME5,MARK4,BMP7,ST3GAL5,SCAPER,RAB29,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,TSPAN5,STX2,FYN,CYP46A1,RAB40B,STON1,MPP2,MXI1,NEK1,SERPINI1,PRPH,PTCH1,SH3GL3,SYBU,WDR47,PKNOX2,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,GDPD5,SLC17A7" Drug 2105_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.99E-05 8.72E-01 4.37E-04 4.92E-03 39 173 "ADRB2,ARNTL,ST3GAL5,CHN2,NRXN3,ABCG1,CNTNAP2,CTH,PLPPR4,RGS17,BAIAP2,FYN,STON1,GUCY1B1,BACH2,HSF2,FAM69A,MMP16,GIT1,TAGLN3,PCDH9,SERPINI1,PRPH,ENOX1,RGS4,SH3GL3,ASAP3,DZIP1,ARHGAP26,IQSEC2,RGL1,SYT1,SYNE1,HEY1,TNS1,SSBP2,RPRM,UBE2H,SLC17A7" Drug CID000000224 AMP group Stitch 2.02E-05 8.83E-01 4.37E-04 4.92E-03 99 579 "ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADRA1D,ADRA1B,LRFN2,ADRB2,AK2,SEMA6A,AMPD2,AMPD3,LRFN1,APC,NT5C3B,APOC2,LGR5,ALDH7A1,DST,GYG2,CALM1,CARS,P2RX6,CD38,ENTPD2,DGKI,LRBA,UBE2L6,FHL5,AKAP6,CREM,CS,EARS2,DGKB,DGKG,DCTN1,DYNC1I1,FARSB,EDN1,ENO2,GPHN,ZNF461,ACSL4,STRADA,PRKAG2,UBE2E3,AK8,TPK1,CAMKK2,RAPGEF6,ACSS1,GCK,PPARGC1A,CRCP,GNAL,GPR12,LPAR4,CPT1C,IDH3A,LIG4,P2RY13,P2RX7,P2RY1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PKM,EXOSC10,PRKAB2,PRKACB,PRKCB,MAPK3,PRPSAP2,MASP1,PTH1R,ACSS3,RET,RNASE1,SARS,FNIP1,FNDC3A,SEPHS1,NMNAT2,SST,ADHFE1,SLC19A3,TLR4,TRPM2,HSPBP1,UBE2H,VIPR2,P2RY12,ZNF195" Drug 5478_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "BIN1,PPP4R4,PDE8B,CFLAR,RUNX1T1,CD86,PLAA,ARHGEF6,SPOCK2,LYPD1,PLXNC1,FGFR1,PRELID3A,ZNF44,IQGAP2,GFER,GNAO1,GRIK5,NXPH3,LIG4,LSS,AFDN,MSR1,CNOT4,NOVA2,PLCD1,LRP12,PPARA,RELN,RGS4,GSTCD,RPS6KA2,PKNOX2,LIMCH1,ZHX3,PEG10,ARC,SYN2,EXOC7,CRTC1,TUBB1,MAP3K12,EVI5" Drug 4158_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SEMA6A,APBA2,APBB2,APC,SLC2A11,KSR1,CACNA2D1,CALB1,CAST,RUNX1T1,USP2,KCNAB3,SULT4A1,ARHGAP24,ELMO1,C2CD2L,ZNF44,ALDH1L1,SRCAP,GRM8,HLF,IL6ST,NEFM,NTRK2,PURG,ELOVL2,PTPRB,ZMAT4,RGS12,KLHDC8A,CARF,SEMA6D,PKNOX2,SNAP25,PDZD2,ATP10B,PCDHGB6,PCDHA5,UGT8,WIPF1,XRCC4,NT5M,EVI5" Drug 2432_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "DOC2A,APBB2,KIF1A,CACNA1I,CACNA2D1,CHN2,NCOR2,OPTN,DCTN2,TRAF3IP2,SRCAP,GLYR1,PRUNE2,SOX21,PADI2,TJAP1,LAMA2,MAP4,NRCAM,NTRK3,PDE4D,FSD1,PPARA,PRPH,BCAS3,RFX2,RGS12,ZFHX4,TCP11L1,SH3BGR,SLC14A1,SNCA,ATP10B,PHLDB1,RPGRIP1L,PCDHGA10,TIAM1,TK2,CHST5,UGT8,NT5M,SLC17A7,PLSCR4" Drug 5877_UP Azaperone [1649-18-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AGT,ADAM23,GYG2,MYRF,CACNA1A,CBFA2T2,QKI,CSF1R,FAM131B,GPRASP1,MFAP3L,SLC12A6,TENM1,VPS26C,DLC1,FCGRT,FER,PRRC2B,GRM8,ICA1,SCIN,KHK,PACRG,MAPT,MATN3,MMP16,MX1,NTRK2,SERPINI1,PRPH,RIPOR1,TCP11L1,RPS6KA2,PPP4R3A,ELMO2,SMARCD3,FAIM2,SSTR2,TK2,CABIN1,OSBP2,NT5M,KCNAB1" Drug 6026_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ALK,BIN1,ARHGDIG,CDK13,MARK4,GYG2,CACNA1I,CACNA1G,CAMK2B,CDH2,B4GALT6,SH2B1,SNCAIP,IPCEF1,SPOCK2,PLPPR4,SPOCK3,DUSP9,AASS,ERBB4,BAIAP2,PRELID3A,NSG1,DISC1,GCK,GRM8,AFDN,MMP17,NF1,NPR2,PAX6,PDE4A,C1orf54,ZMAT4,RGS12,KCNIP1,RASA3,ST6GAL1,SLC11A1,JMJD6,OBSL1,CRTC1,NT5M" Drug 3441_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADRA1D,AP2A2,ALCAM,CDC42BPA,MARK4,EIF4G3,ST3GAL5,SCARB1,CRLF1,VAX2,QKI,HINFP,PDE4DIP,GPRASP1,FBXL5,DNM1,CDKL3,SCML2,KAT8,SEMA4D,EFCAB2,B4GALNT1,GRB10,DHX35,INPP5B,ITPKB,KCNF1,TM6SF1,NF1,PRPH,APTX,ZSCAN2,ZNF821,EPN2,SOX3,CAMTA2,POGZ,TNS2,TIAM1,CABIN1,HIRA,MAP3K12,GDPD5" Drug 4088_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "FZD9,DNAH17,ATP2B2,RGS9,PROM1,KSR1,SCAPER,BAIAP3,CAMK2A,CAMK2B,NRXN3,STOML1,AKAP6,CABP1,CSF1R,SRPK3,RASGRP2,NCALD,AGAP2,SIGLEC8,GFER,CSDC2,STMN2,ELOVL5,KCNF1,PACRG,MARK1,MMP16,ADAM22,PDE4B,GPR173,MAPK10,RFX2,RGS4,SCN2B,IZUMO4,ZC3H13,ATP10B,TACR1,TLR4,PIK3R5,TUBB1,SLC30A3" Drug 3859_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NDRG2,APAF1,APLP1,RGS20,SLC2A11,BACH1,LDLRAD4,CAMK2B,SLC16A4,CDO1,CLGN,PICK1,CNTN1,VCAN,DAPK3,TMCC2,DNAH9,DTNA,FRY,ING4,EPB41,ERCC2,FGF13,CAMKK2,KHDRBS3,ITGAM,KCNN1,KIT,IPO5,TM6SF1,KITLG,MMP16,PNMA8A,ASAP3,KANSL3,RBM34,ARC,SMG6,SLC44A1,TIAM1,TIMP4,XRCC4,PRDM10" Drug 4765_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,ADORA1,SEMA4G,MARK4,ATP2B2,BACH1,ADGRB1,NRP2,SYNJ2,SCAPER,CALB2,KYAT1,CDH2,LARGE1,EPS15L1,RCHY1,RUSC2,VPS13B,ZNF589,CAMKK2,FYN,TMEM8B,STMN2,CACFD1,HLF,AFF1,ADAM22,PFKFB2,PLXNB1,NECAB2,POU6F1,SNRK,TCP11L1,EMID1,KDM4B,HECW1,UNC5B,CDK19,SYT5,TK2,TPM2,SLC17A7,SENP7" Drug 6729_UP Erythromycin [114-07-8]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NDRG2,AP2A2,ALK,PKP4,SLC2A11,HAP1,USP2,SCARB1,FOXN3,CHN2,VAX2,IQCK,CSF1,DTNB,DUSP9,HIPK3,ING4,EPHB1,APC2,DLC1,NSG1,ALDH1L1,RUNDC3A,GRIK5,ATXN2L,BACH2,KCNJ5,MYCN,LYRM9,PALM,PGAM2,POU6F1,RASA3,SH3BP2,CNKSR2,NLGN1,SLC11A1,PLCB1,PCDHGB6,FAM189A1,AP4E1,PARP11,NLRP3" Drug 5067_UP Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "APAF1,APOC1,CDK10,PPP4R4,ADGRB1,KSR1,MTMR3,CHN2,CHRNA4,HOMER3,CNTFR,ABCG1,ARHGEF10,CYBB,DMPK,DNAH9,TUBD1,COQ7,MTSS1L,F5,FGFR1,DCTN2,ERAP1,DISC1,MSL3,ITGA7,LSS,MAPT,AFDN,MSR1,LYRM9,MYO7A,PDPK1,GRAMD1C,PTCH1,RGS12,KCTD17,S100B,FRMPD1,ARHGEF40,ATP10B,R3HDM1,ZFP37" Drug 5614_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,FZD9,PPP4R4,MARK4,RASL11B,CA4,CACNA1A,HAP1,CAST,CD86,ARHGAP33,RAB33A,PICK1,WHRN,CSF1R,PHF14,RIMS2,DMPK,DTNB,SRPK3,FGF13,SOX21,ATXN2L,MYT1,NOVA1,NTRK3,PLCB2,PLCD1,MAPK10,ACSM5,CCDC40,KLHDC8A,KCNIP1,CPEB3,CNKSR2,LIMCH1,KDM4B,PHLDB1,ARC,SYT5,WSCD1,HIF3A,PRDM10" Drug 6201_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AP2A2,BIN1,OGT,PPFIA4,APBB2,SLC4A4,PICK1,CREM,CRYM,RIMS2,BRINP1,SPOCK3,CDON,OPTN,MRNIP,LRRC17,STX2,FGF1,FGFR1,AGAP2,NSG1,DLL3,SIGLEC8,GATM,CSDC2,PCLO,CACFD1,KCNJ5,KCNN1,MSI1,ADAM22,MSR1,PDE4D,MARCH1,CCDC40,EMID1,SLC12A4,ZSWIM8,SPTAN1,TK2,TUBB1,KCNAB1,FAM13C" Drug 2493_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SYT13,MARK4,MYOM1,BMP7,CACNA1I,CAMK2G,SEPT7,CHN2,NRG2,CREM,GPRASP1,DAPK1,OLFM1,AFF2,KHDRBS3,TMEM8B,GATM,GPR162,GFER,GPD2,IL6ST,JAK2,L1CAM,SMAD9,MPP2,PDE4A,MAPK7,PNMA8A,NEK11,EMID1,NLGN1,EPN2,BTBD7,SNCA,ARHGAP26,SPTB,LHPP,PLCB1,PCDHGA10,TIAM1,LMF1,KLC2,SLC17A7" Drug 4103_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ALK,CDC42BPA,APC,GAS7,CACNA1I,CACNA1G,ARHGEF2,WHRN,SNCAIP,CSF1,VCAN,DZIP3,ARMCX2,MYEF2,ECM2,EGR3,EPHB1,PTK2B,OLFM1,GCNT2,HPGDS,CNTRL,GUCY1A1,ICA1,MARK1,GIT1,MX1,MYT1,NOVA2,LRP12,MAPK7,SNRK,SH3BP2,FRMPD1,PKNOX2,LIMCH1,SNCA,JMJD6,PHF24,LAT2,SPHK2,SLC17A7,KCNAB1" Drug 6969_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AK2,FAM131A,SCAPER,CBFA2T2,LHX2,QKI,ENTPD4,SIPA1L1,CYBB,MED12,CDON,EDNRA,OPTN,AASS,ANKMY1,RRAGB,ZNF589,ANKFY1,AFF2,GAD1,SRCAP,GLYR1,STON1,IL6ST,MAP4,MAPT,ADAM22,PPP2R2B,PTPRE,PTPRN,GTDC1,RFX3,RPS6KA2,EPN2,ZKSCAN3,SP2,IQSEC2,ASTN2,WSCD1,SYNE1,RUNDC3B,SEMA3B,GJC2" Drug 6498_DN Protriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADCY6,BIN1,EPB41L5,APLP1,PDE8B,MARK4,GYG2,C5,CAMK2G,MAGI1,CACNA2D2,B4GALT6,AATK,ARHGAP24,DAPK3,DBN1,MFAP3L,DTNA,MTSS1L,KAT8,SRCAP,ELOVL5,INPP5B,IPO5,MAPT,MITF,MPP2,N6AMT1,PCDH9,POLG,CCDC25,EMID1,ABLIM3,PKNOX2,CXXC4,LIMCH1,TSPYL2,TROVE2,SS18,CEP68,NSFL1C,EXOC7,FBXW11" Drug 6743_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,AGT,APAF1,SLC4A4,N4BP2L1,SCAPER,RUNX1T1,CD86,MAGI1,DLGAP1,HOMER3,SPOCK2,DUSP9,EDN1,HIPK3,ING4,ETV1,AGAP2,NSG1,PRUNE2,CNTRL,ELOVL5,MMP16,ADAM22,TAGLN3,NF1,NNAT,PDE4B,GPR85,PFKFB4,RETREG1,ELOVL2,TMEM231,FAT4,RASGRF1,RGS3,ZFP30,OGDHL,HECW1,TACR1,CABIN1,EMSY,KCNAB1" Drug 4659_DN Equilin [474-86-2]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AMT,CDC42BPA,MARK4,ALDH7A1,NRP2,CBFA2T2,FOXN3,TAOK2,ARMC8,NCOR2,ARHGEF10,DAPK3,IRAK4,ING4,MRNIP,SPEG,ETV1,ST3GAL6,FGFR1,TMEM8B,SYT17,ZNF276,GLI2,CNTRL,SHISAL1,MX1,NDP,MAPK7,PID1,CEP97,SH3TC2,ATXN7,FUZ,UNC5B,ARHGAP26,ELOVL4,CEP68,PHLDB1,TCF4,CRTC1,CABIN1,XRCC4,NDRG4" Drug 4375_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AGT,TRMT9B,FGD2,N4BP2L1,AZGP1,SCAPER,CFAP410,KRIT1,CHN2,QKI,CNTN1,DGKG,SPOCK2,DTNA,EDNRA,AASS,ING4,GCNT2,KCNJ5,KCNN1,MGAT3,ADAM22,TAGLN3,PFKFB2,CEP41,CNTLN,RGS4,EMID1,SH3BP2,CPEB3,SLC6A11,CCDC88A,CXXC4,SPART,PLCB1,TBCEL,DOCK9,PCDHA5,RIMBP2,TPM2,VIPR2,SLC30A3,KCNAB1" Drug 7457_UP Bromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,ADORA1,NME5,APOC1,ARHGDIG,SLC4A4,ALDH7A1,SCAPER,SOCS6,CNTN1,CSF1R,PDE4DIP,CNTNAP2,MFAP3L,CELSR3,MBNL2,OLFM1,OGA,IFI16,KCNJ5,LAMA2,MIA2,LYRM9,NPTX1,NTRK2,RETREG1,PLXNB1,MBOAT7,WDR25,GAL3ST4,RGS3,GSTCD,SBF1,ZNF821,LMO3,MCF2L,TRIM2,TLR4,PARD3,TRPM2,KCNK12,TFIP11,GDPD5" Drug 3876_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NME5,SPARCL1,ALCAM,BEGAIN,APAF1,SPTBN4,ARHGDIG,MARK4,CFLAR,KSR1,CHN2,TPP1,RCHY1,AATK,ARHGEF10,SEC14L5,RUSC2,FAM13A,AASS,ELN,LYVE1,GLYR1,RASSF8,KCNN1,MAPT,MID1,MN1,PCDH9,STRN3,MINDY2,PTPRN,RNASE1,PNMA8A,ARHGEF40,KDM4B,ZC3H13,TROVE2,ARC,DOCK9,CHST8,PIK3R5,TRPM2,XRCC4" Drug 2521_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ALK,APOC1,SHROOM2,ATP6V0A1,BMP7,CA12,CDO1,RAB33A,SULT4A1,CNR1,CNTFR,WHRN,MYRIP,CREM,SNPH,GSDME,HIPK3,TNK2,C3orf18,F5,DLC1,FHL1,NBEA,RUNDC3A,NEFM,NTRK2,PCDH9,PDE1C,STRN3,MAPK7,MAPK10,ZMAT4,PEX26,FAIM2,DOK5,SEPT8,SYP,SLC19A3,TEK,ICAM5,REEP1,SLC17A7,KCNAB1" Drug 1924_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ABHD6,ANK2,NRP2,CFLAR,CBR1,CDH2,ARHGEF10,ARHGAP32,DCTN1,KLHL3,TNK2,COQ7,ERCC2,VPS26C,GAA,TRAF3IP2,DENND2A,GFER,PCDH17,PRRC2B,TJAP1,MAP4,NF1,NPY,NLE1,PLCD1,PLEC,MBOAT7,CYBC1,NUDT11,RXRA,SEC14L1,KBTBD4,SMARCA4,SYT1,EXOC7,WSCD1,KIAA0930,HEY1,PLPPR2,KCNAB1,ITM2C,AAAS" Drug 1689_UP Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "TRMT9B,APBA2,APC,APLP1,SEMA4G,SLC4A4,SLC2A11,CFLAR,SYNJ1,LDLRAD4,QKI,HOMER3,SLC4A8,SH2B1,GPRASP1,DTNA,COQ7,F5,ZNF589,FGFR1,FHL1,TXNL4A,ELOVL5,ZNF862,NF1,NFYA,GSTCD,ABLIM3,PREX2,PKNOX2,SMARCC2,SMARCD3,TSNAXIP1,SPTAN1,ZBTB43,TROVE2,SAMSN1,CEP68,PLCB1,ZNF34,ZKSCAN5,VIPR2,REEP1" Drug 7323_DN Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AP2A2,APOC1,EIF4G3,C5,LRRFIP1,VAX2,CREM,ENTPD4,RUBCN,KIAA0586,DBT,TSPAN5,MRNIP,BAIAP2,FAM49B,SYT17,INPP5K,ACOT7,JAK2,KCNH2,LSS,MPP2,ZNF862,NFYA,RETREG1,PLXNB1,POLG,PTPN13,CEP97,ZCWPW1,PPP4R3A,ZKSCAN3,LHPP,DIP2A,STX1A,NSFL1C,TACC1,EXOC7,TBL1X,TRIM2,BEX4,CABIN1,TPM1" Drug 3941_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SEMA6A,BEGAIN,ADAM23,P2RX6,CDH2,LHX2,LY86,NCOR2,DNAH9,SHANK1,EDNRA,RASGRP2,IGSF6,REEP2,PTK2B,CSPG5,NEU3,LYVE1,POLL,STON1,GRIK5,HLF,CNOT4,ELOVL2,C1orf54,KCNIP1,STUM,RASA3,FRMPD1,ASAP3,PKNOX2,SLC8A1,LIMCH1,PDZD2,NMNAT2,HECW1,PLCB1,CUX2,DOCK9,PIK3R5,UGT8,FLRT2,PARP11" Drug 5437_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADRA1D,AK2,SRPX,EPB41L5,ARHGDIG,MARK4,BAIAP3,PLEKHB1,ARHGEF6,AKAP7,C2CD2,TBC1D5,NCALD,ANKMY1,FGFR1,SEMA4D,INPP5K,MSL3,GPER1,IL6ST,KHK,KPNA5,MITF,ADAM22,CNOT4,NLE1,TMEM104,EMID1,PPP4R3A,ZNF430,NSFL1C,VPS13A,ASTN2,EXOC7,IQCE,RPGRIP1L,CHST8,HIRA,UBE3A,KCNK12,ZBTB14,SPHK2,GDPD5" Drug 3905_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AP2A2,CDC42BPA,EPB41L5,SEMA4G,RGS20,CDK13,NCOA1,ATP2A2,ALDH7A1,BAIAP3,CA12,SCARB1,SULT4A1,CREM,RIMS2,DUSP9,MBNL2,PLXNC1,EIF4G2,DLL3,OGA,TMEM8B,DISC1,GCNT2,SRCAP,RAB30,GPD2,KHK,TM6SF1,MMP17,CNOT4,NPTX1,RGS12,ASAP3,PKNOX2,LIMCH1,SNCA,SPTB,CLSTN2,WSCD1,SLC44A1,TNS1,PHTF2" Drug 6726_DN Ioversol [87771-40-2]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,ARHGDIG,KIF1A,CCNT1,ARHGEF1,SEPT7,WHRN,NRG2,CRMP1,CSF1R,VCAN,CNTNAP2,MRNIP,FYB1,SIGLEC8,INPP5K,USP19,LYVE1,COPS8,MSL3,GPD2,STON1,KCNN1,MAP4,MGAT3,NF1,NOVA1,PRKAR1B,PRPH,PTPRN2,KIRREL1,NEK11,MYH15,UNC5B,ARHGAP26,LHPP,TROVE2,RPGRIP1L,PCDHA5,THRA,TRIO,VGF,HPS4" Drug 3505_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "C1QTNF1,ALCAM,CFLAR,SCAPER,GYG2,MYRF,CFAP410,CDH2,FOXN3,DOCK4,JAKMIP2,PLPPR4,TMCC2,DTNB,EDNRA,PLXNC1,TENM1,MTSS1L,DCTN2,ICA1,NDP,PCDH9,PFKFB2,PIK3R1,STRN3,MINDY2,GRAMD1C,TRIM68,TCP11L1,SCN2B,SH3GL3,FAM214B,CCDC88A,CXXC4,IZUMO4,PCDHGA10,PCDHA5,TIMP4,TRIO,XRCC4,GDPD5,ITM2C,FAM13C" Drug 2302_DN Ofloxacin [82419-36-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AMPD3,APOC1,HAP1,CAMK2G,CNOT8,SLIT2,TPP1,FAM189A2,TBC1D5,ACSL4,SEMA4D,SEPT9,POLL,GNG4,BTN2A1,ATXN2L,INPP5B,LIG4,LMO2,MATK,NEK1,NF1,SETD4,PALM,STRN3,ELOVL2,TRIM68,FBXW7,TCP11L1,MAPK12,SH3BP2,FNDC3A,PPP4R3A,EPN2,KDM4C,IQSEC2,ST5,ELOVL4,PLCB1,EXOC7,KIAA1107,ZNF45,RNF170" Drug 4505_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADD2,APAF1,CDK13,AZGP1,BMP7,LDLRAD4,CACNA2D1,CBS,CRLF1,TAOK2,LHX2,STOML1,HOMER3,AKAP6,COL9A3,NCOR2,ARHGEF10,ARHGEF4,CYBB,SEMA3D,COQ7,EPHB1,FLT1,ZNF44,GDF9,GSN,LAMA2,SMAD1,MAP2,ADAM22,NOVA2,PTPRH,ZSCAN2,CCDC40,ZMAT4,RGS3,HKDC1,SLC6A11,FAIM2,ZHX3,ADGRL3,OSBP2,SPHK2" Drug 3581_DN Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,GAS7,PPFIA3,SHROOM2,CDC14B,PPP4R4,ARRB1,MARK4,SLC4A4,ALDH7A1,LDLRAD4,SULT4A1,AKAP7,ABI3BP,SH2B1,GREB1,LYPD1,EDNRA,ING4,ACSL4,SCML2,SCARA3,ICA1,INPP1,KCNN2,LMO2,CNOT4,CCSER2,GTDC1,TCP11L1,EMID1,SH3BP2,NLGN1,SLC6A8,LIMCH1,KDM4C,ZNF423,SPTAN1,ZNF34,ZKSCAN5,XRCC4,REEP1,GDPD5" Drug 2712_DN Sulfameter [651-06-9]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,APAF1,APBB2,PPP4R4,ARRB1,BACH1,HOMER3,CLOCK,CREM,SH2B1,OSBPL3,VCAN,DOCK4,DTNA,CELSR3,ING4,ZNF589,GNG4,LILRA2,MAP4,NF1,OCRL,OGG1,PCDH9,PLTP,ZDHHC14,FBXW7,CLIP1,SH3BP2,SLC11A1,KDM4B,SS18,KIAA1107,CRTC1,TK2,TMPO,TPM2,REEP1,MAP3K12,EVI5,GDPD5,UBE3B,PHTF2" Drug 5446_UP Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,ADORA1,ADORA2A,KIAA1324,LTBP4,BIN1,APAF1,APC,GAS7,ATP2B2,HAP1,CAMK2B,USP2,ARHGAP33,TPP1,DCAF4,JAKMIP2,HIPK3,BAIAP2,HPCAL4,GSTM5,HNMT,ITPKB,KIT,MAP4,MMP16,GIT1,NEFM,TMOD2,PLTP,GDPD2,RASGRF1,RGS12,KCNIP1,SEMA6D,CNKSR2,PDZD2,DOK5,ZHX3,DMXL2,ZEB1,SLC30A3,PLSCR4" Drug 2657_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASPHD1,ASIC1,ADORA1,DOC2A,TRMT9B,AMPD3,APBB2,CDK13,BAIAP3,CFAP410,CA4,SCARB1,ARHGAP33,SLIT2,ABI3BP,NRG2,AATK,LRIG1,ARHGEF10,PDE4DIP,GIT2,MFAP3L,SCARA3,SIGLEC8,SRCAP,ADAMTS13,SEPT4,PPARA,CNNM2,ZSCAN2,FAM184A,TCP11L1,SNAP25,KDM4C,SPTAN1,IQSEC2,SYT5,SMG6,PCDHGA10,AP4E1,TPM2,ZBTB38,KCNAB1" Drug 3884_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,SYT13,BEGAIN,BIN1,APAF1,CDK10,NUMB,NRP2,MTMR3,CACNA1I,HAP1,RUNX1T1,RCBTB2,RIPOR2,ECM2,FGFR1,KHDRBS3,GSTM5,SOX21,C2orf72,LAMA2,LSS,MAPT,MID1,MSR1,TAGLN3,PDE4A,PLCD1,PDZRN4,STRN3,CEP41,MARCH1,C1orf54,ENOX1,CARF,LIMS2,ATP10B,TBCEL,DMXL2,TRPM2,UCHL1,XRCC4,JPH3" Drug 5780_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,NME5,APAF1,ATP2B2,KIF1A,MYRF,MAGI1,CHN2,AKAP5,IPCEF1,ARMCX2,PLPPR4,ECM2,EDIL3,EDN1,PLXNC1,EZH1,CORO2B,FGF1,OLFM1,PDLIM5,NSG1,SRCAP,ATXN2L,SCIN,JAK2,KCNH2,AFF1,NOVA1,GPR85,PPP2R2B,PTN,ACSS3,CCDC40,RGS4,KCNIP1,KIAA1107,ZFPM2,TK2,TLR4,CA14,WIPF1,KCNAB1" Drug 4099_DN Alprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASPHD1,AMH,GAS7,CDC14B,PDE8B,ATP1A3,MYRF,BAIAP3,CACNA1A,ARHGAP33,LHX2,HOMER3,NCOR2,CNTNAP2,RIMS2,PLXNC1,AASS,IRAK4,COQ7,MTSS1L,ZNF549,DLC1,FGF1,SEMA4D,FLT1,CINP,ZNF44,LPAR4,DIDO1,ADAM22,PDE4D,RETREG1,PTPRB,CCDC102B,NLGN1,DZIP1,KDM4C,PCDHGA10,R3HDM1,LAT2,REEP1,MAP3K12,NT5M" Drug 7544_UP CP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,AP2A2,BMP7,CACNB4,VAX2,IQCK,WHRN,TBC1D5,GIT2,PARD6A,DTNA,APH1A,AGAP2,AFF2,DISC1,RAB30,ACOT7,INPP1,LMO2,LSS,MBD1,ZNF862,CNOT4,RETREG1,MBOAT7,ZCWPW1,ZDHHC14,EMID1,FBXO11,KDM4C,STX1A,EXOC7,WSCD1,CUX2,TRIM2,TK2,CDK20,METTL3,LMF1,REEP1,SLC30A3,UBE3B,RNF170" Drug 4254_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADGRF5,SEMA6A,GAS7,BACH1,BMP7,CACNA1A,CACNB4,RUNX1T1,FOXN3,ASIC3,COL9A3,ABCG1,CSF1,CSF1R,CNTNAP2,ERC2,PHF14,MFAP3L,DTNA,IRAK4,APC2,PTK2B,CORO2B,NEU3,PRUNE2,GPER1,GRIK5,ITGA7,KIT,NF1,NRCAM,MAPK10,PNMA8A,SNCA,SPP1,SPTB,LHPP,ARHGEF9,ARC,ZNF24,SH3GLB2,NT5M,KAT6A" Drug 4413_UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,CDK13,ATP1A3,CACNA2D1,USP2,COL9A3,HAPLN1,NCOR2,CSF1,CNTNAP2,DBT,KLHL3,DRP2,DTNB,C3orf18,LRRC17,RASGRP2,APC2,HPCAL4,FLNC,RASL10A,GCNT2,GPR162,ADAMTS13,KIFC3,MMP17,ADAM22,NPTX2,GPR85,SNRK,PTX3,RPS20,SEMA6D,SATB1,RASA3,SLC6A8,CLSTN2,FAM189A1,TNS1,XRCC4,KCNAB1,ITM2C,HRASLS" Drug 4333_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADD2,BMP7,CA12,FAM189A2,CNTNAP2,DAPK3,SEMA3D,TNK2,SRPK3,STX2,PRELID3A,ADAM28,FERMT2,HLF,AGFG1,IL6ST,ITGA7,KCNJ5,KIF5A,TM6SF1,NOVA2,NPTX1,NTRK2,OPRL1,PIK3R1,STRN3,PPP2R2B,PRKAB2,MAPK7,RET,RGS4,SLC25A36,KIRREL1,NEK11,SEC14L1,STUM,CPEB3,CXXC4,THRA,TMPO,FLRT2,NT5M,KAT6A" Drug 4382_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NDRG2,KIAA1324,SEMA6A,LTBP4,BIN1,KIF1A,CACNA1I,BAIAP3,LHX2,HOMER3,SNCAIP,RIMS2,RUSC2,EDNRB,EIF4G2,TNK2,PIPOX,DLC1,DISC1,GCNT2,PRUNE2,INPP1,MMP16,MYO7A,NF1,PLCB2,PTX3,C1orf54,ZMAT4,TRIM68,ZFHX4,TCP11L1,FAM214B,SNCA,FAIM2,WSCD1,PCDHGB6,CRTC1,CHST8,PIK3R5,TRIO,ZNF711,PARP11" Drug 2326_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SYN3,NME5,SPARCL1,KCNAB2,APC,SEMA4G,ARHGDIG,USP2,ARHGAP33,CNTFR,RCHY1,CSF1,LRIG1,RASSF2,ARMCX2,REEP2,FCGRT,FGF1,OLFM1,FOLR2,DISC1,SRCAP,GLI2,KCNN1,KITLG,MMP16,ADAM22,PDE4A,PLCD1,PLTP,C19orf57,PPARA,MINDY2,MAPK10,PRODH,STUM,LIMCH1,ARC,GPR161,FAM155A,WIPF1,LAT2,SENP7" Drug 281_DN fludrocortisone acetate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ACTN1,NDRG2,BRAP,EPB41L5,GAS7,PPFIA3,AQP6,PRX,PDE8B,MYRF,CH25H,KCNAB3,ARHGAP33,SH2B1,CSF1,CSF1R,KLHL3,EZH1,PTK2B,OLFM1,SEMA4D,RUNDC3A,GNAO1,RNFT2,ICA1,IGF1,KCNJ5,MMP17,ADAM22,SETD4,PDCD2,RETREG1,RETREG2,SUSD4,SLA,PREX2,KBTBD4,CDK5RAP2,KDM4B,ZHX3,TBL1X,TFIP11,KCNAB1" Drug 2228_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NME5,BIN1,SEMA7A,GAS7,ADGRB2,CFLAR,CACNA1G,BAIAP3,FOXN3,CHN2,TAOK2,STOML1,QKI,SULT4A1,CNTN1,DOCK4,MAML1,DMPK,EDN1,SPEG,AGAP2,DLL3,CPLX2,LYVE1,TAGLN3,NF1,PFKFB2,PLCD1,LRP12,CEP41,MAPK7,C1orf54,SH3GL3,ARHGEF40,SLC9A5,LIMCH1,SZT2,CRTC1,PCDHA5,DNAH7,DICER1,KCNK12,XRCC4" Drug 2332_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AP2A2,BMP7,ARHGEF7,MTMR3,CA12,HIP1R,CBR1,CD38,PLAA,RGS6,VCAN,PPP1R16B,PLEKHA1,MTSS1L,CELF1,MSL3,LILRA2,GRIK5,ATXN2L,ELOVL5,MYO7A,ZNF862,MYT1,NLE1,NECAB2,RGS3,EMID1,SCN2B,GALNT10,MRAS,EPN2,SLC22A4,ZSWIM8,ZC3H13,SPTAN1,ZC4H2,TCF4,RIMBP2,CDK20,PLPPR2,XRCC4,PCBP4,KAT6A" Drug 7557_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,NDRG3,ADCY6,APAF1,APBB2,APC,APOC1,ARNTL,MARK4,ALDH7A1,BAIAP3,CBS,CNOT8,ARHGEF6,IQCK,ABI3BP,ENTPD4,CNTNAP2,PPP6R2,GIT2,EDIL3,EDNRA,APH1A,ST3GAL6,TRMO,PDLIM5,DLL3,DENND2A,MSL3,DIDO1,IFI16,SCIN,ITGA7,PPP3CC,PRKAB2,WDR47,IFT122,LIMCH1,KDM4B,ANKRD12,TCF4,METTL3,PCBP4" Drug 6779_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NDRG2,TRMT9B,KCNAB2,ARHGDIG,RASL11B,CFLAR,CFAP410,NCOR1,DGKB,ARMCX2,C2CD2L,EGFR,F5,OLFM1,PDLIM5,KHDRBS3,CACFD1,IL6R,MAP4,MEIS2,MGAT3,PDE1C,SLC25A23,POU6F1,PPARA,MAPK7,ELOVL2,PTN,RIPOR1,ZSCAN2,MRAS,KANSL3,SNCA,KDM4B,ZSWIM8,IQSEC2,PLCB1,GPR161,TK2,TNS1,FAM155A,UBE3A,EPM2A" Drug 6610_UP Carisoprodol [78-44-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "DDO,APOC1,RASL11B,ADAM23,BACH1,SCAPER,BAIAP3,CACNB4,CAMK2B,FAM149A,ENTPD4,MFAP3L,CHRDL1,DMD,EDIL3,EDNRB,APC2,REEP2,FGF1,GCNT2,GRM8,SOX21,ICA1,KHK,MBNL1,MGAT3,AFDN,ADAM22,NEFM,NOVA1,NLE1,PPP1R1A,MAPK10,MARCH1,KCTD17,FRMPD1,ASAP3,SPTAN1,PHLDB1,CHST5,AMACR,ZNF24,DPF3" Drug 4167_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AGT,AK2,BEGAIN,CFLAR,CACNA1I,CACNA2D1,CALB1,KALRN,B4GALT6,STOML1,NRG2,ARHGEF10,DAPK1,RUSC2,DMPK,EDN1,REEP2,PTK2B,FAM49B,CAMKK2,ZNF44,ALDH1L1,ITGA7,ZNF862,NNAT,NPR2,NTRK2,GPR85,PPP1R1A,MAPK7,KCTD17,SCN8A,ST6GAL1,PKNOX2,SMARCD3,SP4,ATP10B,KIAA1107,ICAM5,R3HDM1,OSBP2,SLC17A7,ITM2C" Drug 3010_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "C1QTNF1,CDC42BPA,APAF1,APBB2,GYG2,THSD7A,CACNA2D2,CBARP,CHGB,RAB26,SIPA1L1,CNTNAP2,USP6NL,DAPK1,SPOCK2,MRNIP,CALCRL,PRELID3A,CSPG5,GALC,ADAM28,GNAO1,PCLO,CACFD1,ATXN2L,SYNPO,SCIN,KIT,MBNL1,LYRM9,NEFM,CNNM2,GDPD2,PNMA8A,FAM214B,HECW1,ST5,TACR1,SSBP2,VSNL1,KLC2,ADAMTS9,KCNAB1" Drug 2577_UP Merbromin [129-16-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "BIN1,SPTBN4,BMP7,CALB2,CBR1,CDO1,CLCN3,CSNK1E,VCAN,PDE4DIP,CNTNAP2,USP6NL,DAPK3,DBT,RHOBTB1,E2F5,COQ7,CDKL3,PTK2B,GALC,ZNF276,GPD2,GSN,PADI2,NCKAP1L,KHK,KIF5A,LIG4,NEK1,CNOT4,NTRK2,P2RY1,BCAS3,CCDC88A,SNCA,ZHX3,SPP1,NXT2,PCDHGA10,PIK3R5,UGT8,ZBTB38,SH3GLB2" Drug 5266_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SEMA6A,APC,APLP1,DNAH17,MARK4,CA4,ARHGEF2,CLGN,CRLF1,RASSF2,JAKMIP2,ZNF804A,HSD17B14,ENO2,EZH1,FGFR1,IQCG,RAB30,GNG4,STON1,PCLO,GRB10,CACFD1,ICA1,ITPKB,MATK,ADAM22,NF1,SETD4,PLEC,PTPRE,TMEM231,ZFHX4,ZNF821,CXXC4,ZC3H13,TRIM2,PCDHA5,RUNDC3B,ZKSCAN5,EMSY,EPM2A,SENP7" Drug 4525_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AGT,EPB41L5,PPP4R4,ARHGDIG,ALDH7A1,ADGRB2,CACNA1G,CPS1,RGS6,VCAN,SPOCK3,CDON,COQ7,F5,ZNF589,FGF1,SEMA4D,AFF2,PRUNE2,GRIK5,ICA1,MGAT3,AFDN,NCAM2,RASGRF1,KHDRBS2,RGS12,PNMA8A,EMID1,RTN1,RASA3,ASAP3,PREX2,PKNOX2,SNCA,TSNAXIP1,ADGRL3,SZT2,ICAM5,R3HDM1,SPHK2,KCNAB1,FAM13C" Drug 3504_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ALCAM,TRMT9B,APBB2,DDO,SEMA4G,SLC2A11,ADGRB1,LDB2,SCARB1,ARHGAP33,FOXN3,CHN2,CHRNA4,DMD,PLXNC1,LRRC17,MALT1,ELOVL5,MPP2,ADAM22,ZNF862,PDE1C,PDE4D,SMOX,LRP12,POU6F1,MAPK10,DCHS2,C1orf54,KLHDC8A,SLA,PKNOX2,SNCA,ARHGAP26,CDK19,TACR1,PCDHGA10,TNS2,SLC35G2,FAM155A,VGF,WIPF1,NDRG4" Drug 4301_UP Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SPARCL1,PKP4,APBB2,AQP6,PTCH2,N4BP2L1,NRP2,CFAP410,SLC16A4,SCARB1,SRSF11,STOML1,SUSD5,EDN1,MBNL2,MRNIP,REEP2,ST3GAL6,FGF12,AGAP2,RUNDC3A,IL6ST,KCNQ3,KIF5A,KIFC3,AFF1,ADAM22,NEK1,NELL2,PDE4D,STRN3,LRP12,POU6F1,DZIP1,TROVE2,SYN2,COBL,TCF4,TK2,TMPO,FLRT2,LAT2,EPM2A" Drug 3745_DN Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,AP2A2,C1QTNF3,SCAPER,CACNA1A,CAST,SYNGR3,ARHGAP33,LARGE1,PLEKHB1,HAPLN1,CRY2,CSNK1E,SLITRK5,SGSM2,OPTN,EIF4G2,MRNIP,SPEG,KAT8,ZNF589,FGF1,EFCAB2,PDLIM5,PRELID3A,SEPT9,RAB30,GNG4,INPP5B,MINDY2,CEP97,ZCWPW1,MCMBP,ZFP30,DOK5,TROVE2,COBL,RPGRIP1L,TIMP4,TK2,VGF,VIPR2,TIGD6" Drug 4745_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "APC,ARSE,N4BP2L1,LDLRAD4,HIP1R,ASIC3,LY86,ABI3BP,CPS1,CNTNAP2,CYBB,RASSF2,MAML1,DAPK3,MFAP3L,DMPK,DUSP9,SNX29,HIPK3,HEYL,PTK2B,OGA,SRCAP,GNAO1,GSTM5,GUCY1A1,KCNH2,KIT,NTRK2,PDE1B,PLTP,RELN,CNTLN,RASA3,SH3GL3,KANSL3,MYH15,ARHGAP26,PHLDB1,SYT5,VIPR2,WIPF1,PRDM10" Drug 1479_DN Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ABR,AP2A2,APOC1,PPFIA3,CDK10,KIF1A,MPDZ,BCL7A,SYNJ2,SPAG9,SCARB1,SMARCAL1,DTNA,SUGP2,EPB41L2,EZH1,PRKAG2,PDLIM5,GNG4,GPR37,CACFD1,HSF2,ITPKB,LIG4,MATK,LRP12,PTPN13,FNDC3A,EPN2,ELMO2,KDM4B,LHPP,CLASP2,TRIM2,BEX4,TRIO,UBTF,PLPPR2,VGF,LMF1,NDRG4,MPPE1,PHTF2" Drug 2486_UP Trimethadione [127-48-0]; Up 200; 28uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "MTUS1,AMH,BIN1,PKP4,APC,MPDZ,CFAP410,CACNA2D1,THSD7A,HAP1,SLC16A4,CDO1,CACNA2D2,COL9A3,AKAP12,EDIL3,FER,FGF13,AGAP2,DCTN2,FOLR2,SIGLEC8,PCDH17,HPGDS,CACFD1,KCNJ5,KIFC3,LAMA2,MAP4,ADAM22,MSR1,NINJ2,PCDH8,CEP41,RELN,PTPRH,PTPRN2,TCP11L1,SNCA,TMCC1,HECW1,PEG10,CLSTN2" Drug 3871_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,ALCAM,CHRD,NRP2,CACNA1I,CACNA1G,CAMK2B,QKI,CNTN1,CNTNAP2,SEC14L5,CYBB,SV2B,RASGRP2,FGFR3,CAMKK2,KHDRBS3,FYN,GLYR1,MSL3,GRIK5,TJAP1,KCNJ5,KIT,MAPT,MID1,AFDN,MYT1,NNAT,NPTX2,NTRK3,C19orf57,ZSCAN32,TCP11L1,RPS6KA2,SATB1,ZFP2,SLC2A5,IZUMO4,SYP,DOCK9,TRPM2,SLC30A3" Drug 3424_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "FZD9,SRPX,BIN1,PDE8B,SLC4A4,N4BP2L1,ADAM15,CFLAR,ARHGEF7,CA4,HAP1,SOCS6,RAB28,ABI3BP,CSF1,FAM169A,RIMS2,EXOG,RCAN1,HSD17B14,EZH1,FAM198B,FHL1,IQCG,ALDH1L1,INPP1,ITPKB,KCND1,MBD1,KITLG,NPR2,PPP2R2B,ASAP3,LIMS2,BTBD7,ZKSCAN3,COA1,CAMTA2,THSD1,PLCB1,DICER1,TK2,TIGD6" Drug 7322_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADORA2A,NME5,AMPD3,APBB2,RASL11B,ALDH7A1,SCAPER,ARHGEF6,CNTFR,AKAP7,CSF1R,ARHGEF10,PARD6A,DTNA,VPS13B,DLC1,PRELID3A,CSDC2,TXNL4A,CACFD1,ATXN2L,ELOVL5,INPP5B,MAPT,ADAM22,NF1,MTRF1L,POU6F1,TMEM104,PTCH1,ZSCAN2,RGS12,ZNF821,MRAS,LIMCH1,RBM34,TROVE2,ARHGEF9,TMPO,TNS1,WIPF1,ITM2C,ACTR3B" Drug 6478_DN Dioxybenzone [131-53-3]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AP2A2,AK2,SEMA6A,BIN1,CDC42BPA,BCAS1,MARK4,STX16,AKAP7,ABI3BP,BAG4,PDE4DIP,CNTNAP2,GIT2,CELSR3,EGFR,NCALD,SEMA4D,PRELID3A,MSL3,IPO5,MATK,NF1,PDE4B,PPP5C,PRPH,PTN,ZSCAN32,SAFB,SLC6A8,SPART,TROVE2,NXT2,TACC1,CRTC1,CHST8,BEX4,VGF,VLDLR,CLDND1,XRCC4,EVI5,ST7" Drug 6270_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "BIN1,SEMA7A,SYNJ2,CACNA1A,KYAT1,CCNT1,B4GALT6,TAOK2,VAX2,AKAP7,NRG2,DCAF4,DOCK4,RCAN1,COQ7,DLC1,KAT8,BAIAP2,FAM49B,SRCAP,HNMT,KCNF1,NPR2,PALM,RETREG1,NLE1,PPARA,CEP97,RNASEL,DCUN1D2,GSTCD,FBXW7,KCNIP1,ZNF331,FNDC3A,FAM214B,RBM34,CDK19,EXOC7,DNAH7,TMEM121,METTL3,HPS4" Drug 3738_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ASIC1,AP2A2,C1QTNF3,APC,CDK13,ADGRB2,TAOK2,CNTN1,NRG2,NCOR2,AATK,PDE4DIP,SLITRK5,CHRDL1,RCAN1,FCF1,EIF4G2,FGF1,PDLIM5,DISC1,GLYR1,GRIK5,KIFC3,LMO2,NF1,NFIX,FSD1,MAPK7,DZIP1,OGDHL,ZNF415,TSNAXIP1,DDN,CEP68,PHLDB1,DOCK9,CRTC1,CHST8,GPR161,THRA,TK2,UGT8,LMF1" Drug 4351_DN Quinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,ASIC1,ADRA1D,AK2,CDC42BPA,APBA2,ARRB1,NCOA1,MTMR3,GYG2,CA4,HAP1,CRLF1,STOML1,WHRN,DAPK3,MFAP3L,DMPK,DTNA,HIPK3,EGFR,EIF4G2,STX2,FECH,AGAP2,PDLIM5,OGA,RAB30,KIT,CNOT4,SLC25A23,ELOVL2,CCDC40,CCDC25,TCP11L1,SMARCD3,TMCC1,ZHX3,STX1A,PLCB1,ZNF34,VGF,SPHK2" Drug 983_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ABHD6,CDC14B,BCL7A,BMP7,SYNJ2,ARHGEF7,CCNT1,SRSF11,B4GALT6,AKAP7,NECTIN3,ENTPD4,NCOR1,SOCS5,PDE4DIP,PPP6R2,SPATA2,FBXL5,PHF20L1,F8,FAM49B,ZNF276,TXNL4A,GRB10,FICD,ATXN2L,PDCD2,RETREG2,MINDY2,PRKAR1B,PRODH,NKAIN1,QDPR,ROBO1,MAPK12,ZKSCAN3,MAPKBP1,PDZRN3,SPART,ASTN2,IQCE,KIAA0930,CABIN1" Drug 1895_UP Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "C1QTNF1,SEMA6A,LTBP4,SYT13,PPFIA3,SLC4A4,N4BP2L1,MPDZ,SYNJ2,ARHGEF7,CAPN3,CD38,TAOK2,CLTB,ABCG2,ARHGEF6,CNTFR,SPOCK2,KLHL3,RACK1,INPP5K,ARFIP1,IFI16,IL6ST,MITF,GIT1,MX1,NTRK2,OGG1,FSD1,CNNM2,GAL3ST4,RGS12,ST6GAL1,ZHX3,NXT2,ST5,EXOC7,PIK3R5,TRPM2,TSN,REEP1,PLSCR4" Drug 5789_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ACHE,ADD2,ADRA1D,NME5,BIN1,SLC4A4,PROM1,SYNJ2,RUNX1T1,ARHGAP33,WHRN,NCOR2,SPOCK2,EXOG,EDN1,EDNRA,CNNM1,ZNF549,FLT1,DCTN2,PRELID3A,GLI2,POLL,LILRA2,GPER1,CACFD1,JAK2,MAPT,KITLG,LRRN3,PRKCB,C1orf54,RASGRF1,KCNIP1,RASA3,PKNOX2,OGDHL,FAIM2,HECW1,DOCK9,SLC19A3,TRIO,KCNAB1" Drug 4811_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NME5,AMPD3,CACNA1G,BAIAP3,CFAP410,CALB2,RUNX1T1,CBFA2T2,CLGN,EPS15L1,ARHGEF6,NECTIN3,CRY2,CTH,DCAF4,SPOCK3,HS3ST2,DTNB,SEMA3D,EIF4G2,NRN1,TMEM8B,GPER1,ADAMTS13,ICA1,KCNB1,NF1,NPTX1,P2RY1,PDE4D,CYTL1,NLE1,MBOAT7,CPEB3,PKNOX2,KDM4C,AP4E1,GPR161,CABIN1,FAM155A,VIPR2,ZNF24,NT5M" Drug 4435_DN retinoic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "C1QTNF3,APBB2,MPDZ,ARHGAP33,FOXN3,HINFP,AATK,PDE4DIP,DAPK3,PLXNC1,NCALD,SCML2,PRELID3A,B4GALNT1,ERAP1,COPS8,POLL,KCNMB4,STON1,HSF2,ICA1,SCIN,MEF2C,PFKFB4,PIK3R1,MINDY2,CNNM2,WDR25,CNTLN,KIRREL1,RPS6KA2,ATXN7,DZIP1,ARHGEF40,SMARCD3,MYH15,SNCA,CHST8,TMPO,FAM155A,UGT8,SEMA3B,NAV3" Drug 5688_DN Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AMT,PPFIA3,ARRB1,CFLAR,KYAT1,SCARB1,BAG4,ENTPD4,PDE4DIP,DZIP3,GIT2,RHOBTB1,BAIAP2,CNTRL,RNFT2,HNMT,MAPT,GIT1,ADAM22,NEK1,SLC11A2,OPA1,SLC25A23,PRODH,PRPH,WDR25,PTPRE,SUSD4,CCDC25,RXRA,LIMCH1,SPATA7,ERC1,ELOVL4,VPS13A,AP4E1,SLC44A1,TPM1,UBE2H,VGF,REEP1,PCBP4,MPPE1" Drug 919_DN carbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ABHD6,CDK10,SYNJ2,GYG2,KYAT1,QKI,NCOR1,CTH,PPP6R2,DBT,LYPD1,PARD6A,MAMLD1,PLEKHA1,ANKMY1,FHL1,NOP56,FAM49B,MPP6,GHR,TXNL4A,GPER1,SLC2A6,NF1,NPR2,KCTD15,PRPH,SAMD9,ROBO1,ASAP3,SYBU,SLC6A8,SIRT2,ZKSCAN3,SMARCD3,ERC1,ZBTB43,LHPP,SYT1,ASTN2,TMEM121,VGF,MPPE1" Drug 3215_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "NDRG2,SPARCL1,ALCAM,BCAS1,CDK13,ATP1A3,ATP2A2,ADGRB1,CFLAR,SGCE,BAIAP3,CA4,ARHGEF2,FAM189A2,BAG4,ARHGEF4,MFAP3L,SPOCK3,GAD1,ERAP1,IL6ST,INPP5B,KCNN1,MMP16,MSR1,TAGLN3,NF1,PDE1C,PPARA,PPP5C,RIPOR1,CCDC40,ZNF493,TCP11L1,LIMS2,ARHGEF40,SLC14A1,CDK19,SLC44A1,RIMBP2,TNS1,TPM2,SLC17A7" Drug 3414_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "DOC2A,AMPD3,APBB2,PPFIA3,RGS20,CAMK2B,KYAT1,ZMYM4,FAM189A2,SNCAIP,CSF1,CNTNAP2,GREB1,JAKMIP2,SPOCK3,TMCC2,DMPK,DPH1,RCAN1,SUGP2,DLC1,TPK1,POLL,CACFD1,GSN,KCNB1,KCNQ3,LMO2,MBD1,ZNF862,NTRK2,PRKAR1B,ZDHHC14,ASAP3,BTBD7,ZKSCAN3,CEP68,PLCB1,PARD3,RUNDC3B,ZBTB38,EMSY,GDPD5" Drug 2286_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ADD2,SYT13,AMH,GAS7,MARK4,N4BP2L1,ADGRB2,RGS11,CNN3,CRMP1,TMCC2,EDN1,ING4,APC2,DLC1,ZNF589,FGFR1,OGA,LYVE1,GPER1,GPR37,SYNPO,TJAP1,MYCN,MTRF1L,LRP12,NECAB2,PRKAR1B,PRKCB,SNRK,FAT4,RNASE1,SEMA6D,ASAP3,PKNOX2,SNAP25,HECW1,SPTB,DMXL2,R3HDM1,VSNL1,NT5M,SLC17A7" Drug 6100_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AMPD3,AMPH,FAM131A,ADAM23,CA12,CBFA2T2,CSF1R,CTH,RIMS2,MAML1,ZNF804A,RUSC2,FEM1B,C3orf18,DLC1,ZNF589,FGFR1,FHL1,RAB30,GNG4,INPP5B,IPO5,MAP4,MMP16,ADAM22,GPR85,PLCD1,PRKAR1B,GRAMD1C,WDR25,RIPOR1,ZSCAN2,GTDC1,RGS12,FBXO11,PEX26,SNCA,SYN2,WIPF1,ZFP37,ZNF711,ZNF45,TFIP11" Drug 2809_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "ABR,AP2A2,MARK4,CFLAR,KYAT1,KRIT1,USP2,SYNGR3,PLEKHB1,DZIP3,LYPD1,MED12,EGR3,ERBB2,EZH1,FGFR1,IQCG,ATP2C1,TXNL4A,GLYR1,STON1,IL6ST,KCNH2,MAP4,MPP2,NEK1,PLEC,SLC25A23,MBOAT7,PTK2,RIPOR1,QDPR,PEX26,PDZRN3,ZBTB43,MTCL1,TIAM1,PARD3,CDK20,HIRA,KCNK12,GDPD5,PCBP4" Drug 1476_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "AK2,C1QTNF3,LTBP4,CDC42BPA,ARHGDIG,SLC4A4,CFLAR,ST3GAL5,LDLRAD4,ARHGAP33,CRLF1,HOMER3,BAG4,CREM,CRMP1,RGS6,PPP6R2,MAML1,DMPK,SHANK1,TRMO,OGA,POLL,GRB10,TJAP1,TM6SF1,TAGLN3,NF1,PCBP3,SETD4,PMP22,PRODH,TRIM68,KCNIP1,PEX26,SLC9A5,ZC3H13,ARC,EXOC7,CRTC1,SLC30A3,KCNAB1,RNF170" Drug 6034_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SYN3,SEMA6A,TRMT9B,DDO,MARK4,CALB1,CAMK2B,DLGAP1,CHRNA4,RAB33A,SH2B1,NCOR2,SNCAIP,CNTNAP2,RUSC2,SPOCK3,DMPK,DUSP9,FGF1,FGFR1,DCTN2,KHDRBS3,ZNF44,SIGLEC8,PRUNE2,LPAR4,TPPP,HLF,HNMT,TJAP1,MEF2C,PDE1C,PURG,RGS12,EMID1,SCN8A,LIMCH1,PEG10,SPART,RPGRIP1L,UCHL1,LAT2,DNALI1" Drug 1543_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "RALGAPA1,ASIC1,ABHD6,ADORA1,BIN1,APBA2,APBB2,SYNJ2,CACNA1I,AKAP7,NCOR1,JAKMIP2,TENM1,FGFR1,BAIAP2,FHL1,ADAM28,TXNL4A,STON1,GSN,ELOVL5,TJAP1,IL6ST,KCNJ5,KCNQ3,IPO5,ADAM22,NF1,NTRK2,CDK18,NLE1,PLCD1,PTN,RPS6KA2,ASAP3,UNC5B,ITPRID2,SAMSN1,HIRA,KCNK12,SLC30A3,EPM2A,SENP7" Drug 3190_DN Fendiline hydrochloride [13636-18-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "SEMA6A,CDC14B,SEMA4G,SLC4A4,ATP6V0A1,CFLAR,CA12,SOCS6,CSF1R,CYBB,TBC1D5,VPS26C,F8,SEMA4D,ANKFY1,ZNF44,USP19,TXNL4A,MSL3,SPACA9,MATK,ADAM22,NF1,PRKAR1B,CEP97,RGS12,CCDC25,FBXW7,EMID1,ZKSCAN3,SMARCD3,KIF13A,SEPT8,EXOC7,DOCK9,TMEM121,ZNF34,SLC44A1,CABIN1,VIPR2,SPHK2,TFIP11,EPM2A" Drug 5850_UP Vidarabine [5536-17-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "APC,BLM,MYRF,MTMR7,LHX2,ABCG2,AKAP5,CREM,MFAP3L,C2CD2L,DMPK,MBNL2,EIF4G2,RGS17,RASGRP2,ZNF549,CORO2B,OLFM1,TMEM164,SCARA3,SEPT9,GPD2,KCNF1,ADAM22,FSD1,PRKAR1B,MAPK9,PTPRD,FAM184A,ZMAT4,RET,RGS4,RGS12,FBXW7,ASAP3,SLC4A3,PKNOX2,SMARCD3,SAMSN1,CEP68,SSBP2,REEP1,MPPE1" Drug 4650_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-05 8.95E-01 4.37E-04 4.92E-03 43 198 "LTBP4,SYT13,DNAH17,PTCH2,BMP7,CFAP410,KALRN,USP2,LHX2,SULT4A1,FAM149A,CABP1,RGS6,BRINP1,C2CD2L,DRP2,AASS,ELN,NSG1,FYB1,TRAF3IP2,SIGLEC8,GPR75,SPACA9,IRAK3,IGF1,KCNF1,ADAM22,NRCAM,NTRK3,P2RX7,PCSK5,CNNM2,RGS12,SCN2B,CNKSR2,KANSL3,SNCA,HECW1,SMG6,SLC44A1,TPM2,REEP1" Drug 5216_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "BIN1,SEMA7A,SLC4A4,MPDZ,CFLAR,CA4,CALB2,RUNX1T1,SLC16A4,ARHGAP33,NECTIN3,CRY2,CSF1R,ARHGEF4,RIMS2,ARMCX2,RUSC2,EXOG,DTNA,DNAJB6,TNK2,C3orf18,SRCAP,GLYR1,STON1,ICA1,IL6R,KCNN2,MAP4,NELL2,NF1,NTRK2,MTRF1L,KLK6,SAMD9,ZNF493,TCP11L1,HSPA4L,PLCB1,OBSL1,FLRT2,FXR1" Drug 1240_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "ASIC1,ABHD6,APC,STX16,N4BP2L1,ST3GAL5,CACNA2D2,CHN2,ARMC8,AKAP5,SLITRK5,SPOCK2,PLPPR4,EDIL3,FYN,GAD1,STON1,GUCY1B1,FAM69A,ITGA7,ZNF862,RETREG1,POLG,PRPH,RGS4,NUDT11,TCP11L1,PREX2,ARHGEF40,TSNAXIP1,SAMSN1,RGL1,SYT1,COBL,TCF4,GPR161,THRA,HEY1,TK2,AMACR,LAT2,PHTF2" Drug 3179_UP Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "FZD9,ALCAM,APAF1,RGS20,ATP2B2,CA4,P2RX6,ARHGEF2,DCLK1,RCBTB2,TAOK2,RGS6,PHF14,RIPOR2,TMCC2,DTNA,HIPK3,ING4,ETV1,HPCAL4,DLL3,SESN1,JAK2,KPNA5,PCBP3,NTRK2,CLDN11,PLTP,SDK2,PILRA,RGS12,PBRM1,TCP11L1,CPEB3,LIMS2,FAM214B,TTBK2,RGL1,PLCB1,ZMAT3,WIPF1,XRCC4" Drug 2703_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "DOC2A,ANK2,APBB2,ARRB1,CAST,HIP1R,CBR1,SLC16A4,AKAP7,RCHY1,CTH,ARHGAP32,ZFYVE16,KIAA0753,CNNM1,CELSR3,ELN,RASGRP2,GATM,RUNDC3A,MAP4,NNAT,MINDY2,CEP97,FAM184A,RGS3,RNASEL,RPS6KA2,PPM1E,FRMPD1,IZUMO4,ARHGAP26,TSPYL2,LHPP,ARHGEF9,PDLIM2,TBL1X,PIK3R5,TPM1,UBTF,VLDLR,SENP7" Drug 4018_DN Niclosamide [50-65-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "KCNAB2,ARRB2,ST3GAL5,CA12,CAMK2G,KYAT1,LHX2,RAB26,CRMP1,ARHGEF10,PDE4DIP,SLITRK5,KLHL3,EDNRA,IRAK4,MTSS1L,EZH1,ZNF589,B4GALNT1,SYT17,HAS2,BACH2,MEF2C,MN1,MX1,NDP,POLG,MAPK7,SNRK,ZCWPW1,ZFP30,ARHGEF40,SLC9A5,SMARCA4,LHPP,JMJD6,DNMBP,DNAH7,TNS1,UGT8,NDRG4,MPPE1" Drug 3392_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "ACTN1,ADORA1,ADORA2A,ADRA1D,BEGAIN,AMPD3,MARK4,RASL11B,N4BP2L1,CFAP410,CAMK2G,CAST,RUNX1T1,CDO1,TPP1,CSF1R,ARHGEF10,SEC14L5,RASSF2,TMCC2,EGR3,TNK2,ERCC2,PIPOX,DCTN2,GSTM5,ADAM22,MYO7A,NTRK2,TREM2,CCDC40,SALL1,SNCA,KDM4C,ATP10B,SYN2,SZT2,CRTC1,TRPM2,SEMA3B,KCNAB1,JPH3" Drug 7191_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "NDRG2,MTUS1,APOC1,CDK13,MARK4,ATP2B2,CBFA2T2,FAM189A2,CSF1,PDE4DIP,RCAN1,DTNA,MBNL2,COQ7,CDKL3,VPS26C,ACSL4,BAIAP2,FHL1,MALT1,COPS8,GRB10,GSN,KCNH2,KIFC3,LSS,MAP4,MPP2,PPP1R1A,SAMD9,PTPRN2,RGS12,CCDC25,SEC14L1,ZFP30,SLC11A1,RBM34,PLCB1,VIPR2,MAP3K12,EMSY,SEMA3B" Drug 3469_DN Butacaine [149-16-6]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "ABHD6,EPB41L5,FAM131A,PPFIA3,CFLAR,CFAP410,CAMK2G,TPP1,VAX2,CREM,GIT2,FBXL5,HIPK3,FEM1B,CDKL3,ZNF589,FHL1,ANKFY1,FAM49B,TRAF3IP2,GCNT2,CRCP,GLYR1,LPAR4,SLC2A6,IL6ST,ADAM22,PDPK1,RETREG1,NLE1,SMIM7,SNRK,SLC25A36,CCDC25,EPN2,ZSWIM8,ARHGEF9,PARD3,CABIN1,LMF1,PHTF2,RNF170" Drug 4454_DN thioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "ABR,AP2A2,C1QTNF3,LTBP4,SEMA4G,ADGRB2,MYRF,CBFA2T2,LHX2,IQCK,COL9A3,SLC4A8,SLITRK5,KLHL3,FAM13A,IRAK4,NCALD,FGFR1,IQCG,FYB1,SRCAP,POLL,GPER1,CNTRL,KHK,MAPT,GIT1,NDP,NF1,RAD51D,GSTCD,ARHGEF40,SMARCA4,UNC5B,DDN,KIAA1107,WSCD1,TMEM121,TNS1,UGT8,TRIM9,PHTF2" Drug 5058_DN "Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "APBB2,ADAM15,SRSF11,SLITRK5,DAPK3,DBT,EDIL3,EGFR,STX2,VPS26C,ANKFY1,PDLIM5,ZNF276,SPIN1,GLUL,PCLO,RASSF8,SYNPO,AGFG1,LIG4,MBD1,MBNL1,NEK1,CNOT4,SMIM7,LRP12,PRKAB2,ELOVL2,SBF1,CSRNP3,SEC14L1,KDM4B,PEG10,ZBTB43,CEP68,GPR161,TK2,BHLHB9,UGT8,ZNF45,EVI5,KAT6A" Drug 1221_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.11E-05 9.25E-01 4.49E-04 5.06E-03 42 192 "AMT,ATP2B2,BACH1,C5,IL33,CFAP410,RAB26,ARMC8,CPS1,AKAP12,VCAN,GPRASP1,EDIL3,CNNM1,ING4,MRNIP,ETV1,EZH1,FGF13,SRCAP,MSL3,STON1,DIDO1,SHISAL1,JAK2,TM6SF1,ZNF862,CNOT4,NTRK2,CLDN11,P2RX7,PRKAR1B,TMEM231,CEP97,ZMAT4,STUM,SUPT20H,ST6GAL1,BTBD7,ZNF667,ZC3H13,HPS4" Drug CID000164073 Pkcs Stitch 2.15E-05 9.41E-01 4.57E-04 5.15E-03 45 211 "CALM1,CCK,KRIT1,CHN1,CHN2,AKAP5,AKAP12,DGKG,DAPK3,PARD6A,RASGRP1,EGFR,ERBB4,PTK2B,FGF1,PSD2,MALT1,RAB40B,MYLK2,SCIN,ITGAM,ASPRV1,MARK3,MBP,PIK3C2A,PIK3R1,PKM,PRKCB,MAPK3,MAPK4,MAPK7,MAPK10,PSMA6,PTH1R,PTK2,S100B,MAPK12,SMPD3,ARFGAP1,CDK5RAP2,NSFL1C,SYT1,VAV1,P2RY12,RICTOR" Drug 6891_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.18E-05 9.53E-01 4.62E-04 5.21E-03 41 186 "ABHD6,NME5,MARK4,BMP7,BAIAP3,CBFA2T2,CLGN,WHRN,COL4A5,AKAP12,PDE4DIP,ARMCX2,OPTN,STX2,ACSL4,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MITF,NEK1,PDE4A,SERPINI1,GRAMD1C,PRPH,SH3GL3,CPEB3,WDR47,FAM214B,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,HEY1,R3HDM1,RUNDC3B,SLC30A3,EVI5,SLC17A7" Drug 1228_UP geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-05 9.53E-01 4.62E-04 5.21E-03 41 186 "ALK,N4BP2L1,MPDZ,KSR1,GYG2,CFAP410,NRXN3,ARMC8,COL9A3,ABI3BP,CPS1,CTH,CNNM1,MBNL2,PLXNC1,DIDO1,CACFD1,SOX21,MUM1,MMP16,GIT1,ZNF862,NACA,NF1,NFYA,OXTR,PRKAR1B,RGS4,HSPA4L,ANKRD6,SLC11A1,PDZD2,SOX15,ZC3H13,SPTAN1,IQSEC2,TRIM2,SZT2,OSBP2,SEMA3B,PHTF2" Drug CID000000191 arabinosyladenine Stitch 2.18E-05 9.57E-01 4.64E-04 5.22E-03 124 762 "ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,NME5,AK2,AMPD2,AMPD3,APC,NT5C3B,MADD,PDE8B,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,GPC2,CACNA1A,CACNA1B,CACNA2D1,CALM1,CAPN3,CARS,CBS,CCK,P2RX6,CD38,ENTPD2,LRBA,CACNA2D2,MYL6B,ABCG2,AKAP6,COL4A5,COL11A2,GAL3ST1,GDA,BOC,EARS2,DBI,SLC29A4,DPP6,FARSB,EDN1,F5,F8,FCGRT,PPP1R1B,PRKAG2,AK8,ATP2C1,GCK,SESN1,GPD1,GPD2,LPAR4,GRIA2,GRM2,GRM8,CIT,GUCY1A1,GUCY1B1,TNFAIP8L3,ICA1,IDH3A,IDH3B,IL12A,KCNB1,KCNJ5,KLHL23,MAT2A,MYH3,P2RY13,NF1,NPY,NPR2,OPRL1,P2RX7,P2RY1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ABCB1,PIK3C2A,PIK3R1,PKD1,PKM,POLR2F,PRKACB,PRKCB,MAPK3,MAPK4,NDUFS7,GAL3ST4,RNASE1,RNASEL,RNH1,ZC3H14,ADAL,RYR3,MAPK12,SARS,FNDC3A,TET1,DDN,SST,TK2,ACTR6,PIK3R5,METTL3,UBTF,P2RY12,GAL3ST3,PLD4" Drug 6340_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.24E-05 9.80E-01 4.75E-04 5.35E-03 40 180 "ADRB2,MTUS1,ARNTL,MARCH3,MARK4,ST3GAL5,WASF1,HIP1R,USP2,ABCG1,PDE4DIP,CTH,JAKMIP2,C2CD2L,PLPPR4,ANKRD46,RGS17,ENO2,TAOK3,BAIAP2,NBEA,FYN,GUCY1B1,FAM69A,INPP5B,MEF2C,MMP16,PCDH9,SERPINI1,RETREG1,PLCD1,RGS4,STUM,SH3GL3,KIF16B,WDR47,THSD1,RGL1,SYT1,SSBP2" Drug ctd:C026486 "1,2,5,6-dibenzanthracene" CTD 2.26E-05 9.91E-01 4.75E-04 5.35E-03 135 844 "UNC5A,ADRB2,EPB41L5,DDO,ARNTL,PDE8B,ASGR1,ASPA,ADAM15,GPR146,CFLAR,BMPR1B,ST3GAL5,C5,CA8,PRC1,USP2,CD38,ZNF445,CHN2,NGEF,MAP4K4,ABI3BP,ZNF521,NSL1,NECTIN3,CLOCK,HAPLN1,CRY2,CRYM,CSF1,APPL1,GREB1,DCAF4,DBI,ARMCX4,PITPNC1,HEPH,SLC29A4,NR1D2,RCAN1,ARRDC4,EDNRB,HEYL,KLHL5,TMTC1,ERBB2,FAM198B,FGF1,FGFR3,BAIAP2,MAD2L2,FHL1,POLK,ZMYND15,TRIM16,CGREF1,GCK,GDF1,GPR162,PCDH17,LYVE1,CCDC184,PLCD4,SERP2,FAM107A,HLF,HMGCR,HNMT,CELF5,IGF1,NKD1,DISP2,ITPKA,KCNB1,KCNN2,KIT,LAMA2,STMN1,LIFR,LMO2,MAPT,TM6SF1,SAMD5,MSR1,THYN1,MYCN,P2RX7,P2RY1,TMOD2,PFKFB3,ABCB1,PIK3R1,RASGEF1B,HYDIN,LAMA1,MTMR10,PTPRG,PTX3,PID1,RASGRF2,RGS3,RGS12,LGI2,ROBO2,GLDN,EMID1,HUNK,HSPA4L,SH3GL3,HKDC1,PEX26,SNCA,SPP1,ZNF423,ARHGAP26,THSD1,ST5,SULF2,VPS13A,TRIM2,PCDHB7,PCDHAC2,GPRIN3,DNAH7,ZMAT3,THRA,RASD2,CHST5,AMACR,TUBB2A,CLDND1,ZNF23,REEP1,GDPD5" Drug 5215_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-05 1.00E+00 4.75E-04 5.35E-03 39 174 "OSBPL1A,NME5,BIN1,MARK4,ST3GAL5,CA4,HIP1R,CLGN,CRY2,PDE4DIP,CTH,RCAN1,DNAJB6,ABCC5,MBNL2,SEMA4D,SRCAP,GLYR1,DIDO1,HMGCR,HSF2,ICA1,ZNF862,NF1,OXTR,PLCD1,MBOAT7,KLK6,MORC4,HSPA4L,SGK1,SH3BGR,PPM1E,ZEB1,TRIM2,VLDLR,LAT2,ZFP37,FXR1" Drug 5260_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.29E-05 1.00E+00 4.75E-04 5.35E-03 39 174 "MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,SEC14L5,ARMCX2,TMCC2,OPTN,FAM13A,AASS,HPCAL4,FYN,CYP46A1,STON1,MAP2,MXI1,NEK1,PCBP3,SERPINI1,PLCD1,GRAMD1C,PRPH,SH3GL3,ASAP3,WDR47,PKNOX2,ARHGEF40,ELOVL4,RGL1,STXBP1,HEY1,RUNDC3B,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 2084_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.29E-05 1.00E+00 4.75E-04 5.35E-03 39 174 "ABHD6,ADRB2,MTUS1,ARNTL,MARCH3,ST3GAL5,HIP1R,SPAG9,CHN2,ABCG1,CTH,PLPPR4,RGS17,CDKL3,TAOK3,BAIAP2,FLNC,FYN,LIFR,MMP16,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,PTX3,RGS4,RPS6KA2,SH3GL3,SYBU,KDM4B,ELOVL4,CEP68,RGL1,SYT1,COBL,KIAA0930,SSBP2,PLSCR4" Drug 7530_DN irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-05 1.00E+00 4.75E-04 5.35E-03 39 174 "MAP4K3,APBB2,SHROOM2,NUMB,ARHGEF7,TAOK3,SYNCRIP,AGFG1,FAM69A,JAK2,MEIS1,NF1,CNOT4,PTK2,REV3L,KIF16B,AMBRA1,CHD9,ATF7IP,CDK5RAP2,TMCC1,PDZRN3,DOP1A,CDK19,CLASP2,ERBIN,SYT1,ANKRD28,ANKRD12,CLASP1,DOCK9,PUM2,FRYL,TIAM1,PARD3,TRIO,TRPS1,SSBP2,JMJD1C" Drug 6634_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "GAS7,DDO,AZGP1,SYNJ1,SYNGR3,NRXN3,ENTPD4,CNTNAP2,DGKB,C2CD2L,EDIL3,HIPK3,ZNF391,PIPOX,FGF1,FGFR1,FLT1,CYP46A1,RUNDC3A,GNAL,GRM8,ATXN2L,KITLG,MMP16,NOVA2,NTRK2,PCDH9,GPR85,PPP1R1A,PRKAR1B,PRPH,MASP1,ZSCAN2,GAL3ST4,FRMPD1,ASAP3,CXXC4,OGDHL,SNCA,COBL,TPM1,TRIO,NT5M" Drug 2737_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "BBOX1,CDC42BPA,ATP1A3,KSR1,KALRN,CDH2,DLGAP1,CHRNA4,ABCG2,COL9A3,NCOR2,PDE4DIP,ARHGEF4,RIMS2,BRINP1,MBNL2,AASS,EPB41,MTSS1L,FHL1,GABRA3,ZNF44,SEPT9,GRM8,SOX21,GUCY1A1,MGAT3,MMP16,PTPRB,KHDRBS2,SCN2B,FRMPD1,NLGN1,KANSL3,SNCA,SYT5,TIAM1,RIMBP2,TRIO,TRO,LMF1,FAM13C,TIGD6" Drug 6256_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "BIN1,PTCH2,NUMB,CFLAR,GYG2,CACNA1G,ARHGEF2,SRSF11,QKI,CSF1R,SIPA1L1,ARHGEF4,TMCC2,EGFR,FER,POLL,PCLO,GRIK5,HNMT,IL6ST,KCNH2,MAP4,RETREG1,PLCD1,RETREG2,MAPK7,GSTCD,RASA3,FNDC3A,SYBU,SLC22A4,FAIM2,IQSEC2,TROVE2,PHLDB1,PLPPR2,LMF1,KCNK12,XRCC4,SPHK2,EVI5,KCNAB1,AP3B2" Drug 2781_DN Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF3,DOC2A,APC,FUBP1,WASF1,CBFA2T2,VAX2,CREM,PDE4DIP,MAML1,HIPK3,NCALD,RRAGB,PRELID3A,GLYR1,RAB30,MSL3,HNMT,KCNH2,LSS,MEIS1,MMP16,ZNF862,NACA,NF1,RETREG1,MBOAT7,WDR25,ZSCAN2,SH3BP2,SYBU,SLC22A4,RBM34,TSPYL2,SUPT5H,AP4E1,KAT6B,RUNDC3B,ZKSCAN5,ZBTB14,MAP3K12,DNALI1,SENP7" Drug 4501_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF3,ALK,BEGAIN,AMPD3,APAF1,BCAS1,N4BP2L1,CDO1,STOML1,CSF1,SUSD5,PPP6R2,SEC14L5,ECM2,NCALD,ETV1,GABRB3,SCIN,KCNN1,MAN2A2,KITLG,AFDN,NOVA2,PDE4B,GDPD2,ZSCAN32,PTPRN2,ZSCAN2,ZMAT4,CARF,EMID1,SLC2A5,KANSL3,PKNOX2,HECW1,RBM26,LHPP,KLHL4,PCDHGA10,AP4E1,TNS1,LAT2,KCNAB1" Drug 5813_DN Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "BIN1,SPAG9,CDH2,CNOT8,EPS15L1,RAB28,WHRN,NCOR1,ARHGAP32,RUSC2,SGSM2,TMCC2,DYNC1I1,FECH,FHL1,PDLIM5,OGA,DISC1,COPS8,RNFT2,DHX35,FAM69A,ITPKB,MIA2,MITF,NOVA1,OCRL,FSD1,MAP6D1,SUPT20H,WDR37,ELMO2,LIMCH1,COBL,PDLIM2,SLC35G2,ZNF34,CBX5,NR2C2,UBTF,PLPPR2,LMF1,XRCC4" Drug 5784_DN Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF3,AMT,CDC42BPA,APC,ARNTL,CFLAR,RCBTB2,NRXN3,BAG4,CPS1,HAPLN1,CSF1,DZIP3,AASS,MRNIP,DENND4A,ETV1,ZNF589,SRCAP,RNFT2,GUCY1B1,KIF2A,MATN3,GIT1,PRKAR1B,SAMD9,ELOVL2,PTPRH,FAT4,RXRA,SH3BP2,ASAP3,AMBRA1,KDM4C,ZNF423,DDN,SYT1,SYNE1,DNAH7,BEX4,CABIN1,VIPR2,ZNF74" Drug 5960_DN estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "APBB2,GAS7,KIF1A,CCNT1,SYNGR3,SEPT7,TAOK2,NRXN3,TPP1,HOMER3,SLC4A8,CREM,HINFP,AATK,CSF1R,DMPK,HIPK3,SCML2,FGFR1,FYN,TRAF3IP2,POLL,PRRC2B,INPP5B,KIFC3,NF1,ZSCAN32,PTPRH,RGS4,RXRA,SUPT20H,DZIP1,SMARCC2,LIMCH1,ASTN2,RPGRIP1L,CRTC1,RUNDC3B,TSN,UGT8,ZNF711,SPHK2,EVI5" Drug 1229_DN clozapine; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "MTUS1,APLP1,ARRB2,MARCH3,NCOA1,CAMK2B,SOCS6,RAB28,BAG4,VCAN,SNPH,DTNA,OPTN,EGFR,SPEG,ETV1,FECH,FGF1,OGA,CNTRL,MUM1,MAN1B1,IFI16,L1CAM,SLC11A2,OCRL,PDE4B,GRAMD1C,TMEM104,RIPOR1,TMEM231,RPS6KA2,MAP6D1,HSPA4L,ASAP3,FUZ,PEX26,ZNF667,SNCA,SPATA7,TROVE2,THSD1,SUPT5H" Drug 5517_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ABCD2,APBA2,CDC14B,ATP1A3,ATP2A2,ATP6V0A1,CACNA1I,CACNB4,USP2,MTMR7,TAOK2,CNN3,WHRN,ARHGEF10,MAML1,SPOCK2,BRINP1,LRRC17,BAIAP2,DLL3,GPER1,GRB10,INPP1,KCNB1,IPO5,ZNF862,NF1,OGG1,GPR85,PLXNB1,LRRN3,GDPD2,RPS6KA2,SBF1,CNKSR2,ANKRD6,ELMO2,KIF13A,DOK5,ZC3H13,PLCB1,WSCD1,ZEB1" Drug 2322_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "OGT,CDK13,SLC2A11,CA4,CAMK2B,B4GALT6,PLAA,HOMER3,AKAP7,PPP6R2,LYPD1,PARD6A,KAT8,FHL1,SEPT9,INPP5K,POLL,ATXN2L,INPP5B,KCNN1,KCNN2,MPP2,NFYA,SLC25A23,PLXNB1,STRN3,MBOAT7,PRODH,PTCH1,FAM184A,TCP11L1,SBF1,SH3BP2,ELMO2,BTBD7,SPTAN1,PHLDB1,AP4E1,SLC44A1,CABIN1,WIPF1,HPS4,KAT6A" Drug 1605_UP Clopamide [636-54-4]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG2,CDK10,PDE8B,SLC4A4,ADGRB1,ADGRB2,CA12,CACNA1A,CALB2,SPAG9,CHN2,CNTFR,CNTN1,TMCC2,TNK2,SRPK3,FCGRT,ALDH1L1,SPACA9,CACFD1,PRDM5,NXPH3,LAMA2,MAP4,GIT1,NNAT,DUSP26,POLG,PTK2,PTN,PTPRN,RNASE1,PLPPR3,RXRA,LIMS2,SLC11A1,SNAP25,SPTB,SYN2,CRTC1,DNAH7,VGF,VIPR2" Drug 4615_DN Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AMPD3,STX16,ADGRB2,SYNJ2,SCAPER,CACNA1I,SCARB1,ARHGEF2,CNOT8,QKI,IQCK,BRINP1,MBNL2,MTSS1L,NOP56,GLYR1,HTATSF1,NEK1,NFYA,PLCD1,PRKAR1B,ZSCAN2,SH3TC2,FBXW7,RPS6KA2,MAPK12,ATXN2,SH3BGR,ASAP3,SLA,ELMO2,BTBD7,IQSEC2,THSD1,SS18,TCF4,RIMBP2,ZBTB14,NDRG4,NT5M,MPPE1,SMIM8,RNF146" Drug 2545_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "SYN3,AP2A2,AMH,APBA2,AZGP1,KSR1,CACNA1G,SLC16A4,LARGE1,CRLF1,CHN1,NRG2,CREM,DGKG,HS3ST2,ARMCX1,CORO2B,FHL1,AGAP2,PDLIM5,DLL3,FYB1,NEU3,GPD2,GRM8,TJAP1,ITGAM,KCNJ5,MAP4,MX1,NEFM,NEK1,OXTR,RGS12,SEMA6D,SEC14L1,ZNF821,SLC11A1,ZSWIM8,MCF2L,RIMBP2,TRIO,OSBP2" Drug 4539_UP Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "MTUS1,FAM135A,GAS7,CDK13,NCOA1,SLC4A4,RGS11,NRP2,SLC16A4,SEPT7,ASIC3,VAX2,LY86,CSF1,IPCEF1,DTNB,RGS17,ETV1,FGF1,FGFR1,NSG1,FYB1,SRCAP,GRIK5,ATXN2L,MAPT,P2RY13,NF1,NOVA2,PDE4D,PURG,MAPK10,PTPRB,KHDRBS2,PNMA8A,TCP11L1,SLC2A5,SPTB,SYT5,ZEB1,SSBP2,VGF,KCNAB1" Drug 2115_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "KCNAB2,ATP2B2,KSR1,CACNA1I,CFAP410,LARGE1,MAGI1,LHX2,HOMER3,IQCK,ARMC8,AKAP6,CRMP1,CRY2,ARHGEF4,HIPK3,CDKL3,ETV1,FGF1,FYB1,GLYR1,GNAL,ELOVL5,KCNN1,ADAM22,PCDH9,STRN3,PRKAR1B,BCAS3,GAL3ST4,RGS4,SEMA6D,ZFP30,ASAP3,CCDC88A,BTBD7,TBL1X,TRIM2,CHST8,TK2,RPRM,REEP1,NT5M" Drug 3249_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG2,NME5,AMH,BIN1,CDC42BPA,APC,CACNA1I,CACNA2D1,CBFA2T2,ARHGAP33,DLGAP1,CHRNA4,TAOK2,CNTN1,ENTPD4,ARHGEF4,SPOCK2,LYPD1,DUSP9,MBNL2,GLYR1,GNG4,TDRKH,STON1,KCNB1,PFKFB2,PGAM2,PLCD1,MAPK7,SAMD9,PTN,ZCWPW1,KLHDC8A,TCP11L1,PPM1E,SLC2A5,PKNOX2,CCDC88A,ATP10B,TROVE2,TBCEL,SZT2,PCDHA5" Drug 5385_DN Amoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "APBB2,APLP1,PPP4R4,SYNJ2,MTMR2,PDE4DIP,SPATA2,MFAP3L,RHOBTB1,PARD6A,MRNIP,KAT8,ZNF589,FGFR1,BAIAP2,IQCG,GLYR1,GNG4,GPD2,GPER1,CACFD1,KITLG,MPP2,NF1,STRN3,ELOVL2,GTDC1,RGS12,FBXW7,RPS6KA2,ZNF821,ZKSCAN3,KDM4B,ERC1,ST5,PLCB1,TRIM2,TNS2,SLC44A1,PARD3,CABIN1,HIRA,KCNK12" Drug 2765_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ALCAM,BEGAIN,CDC42BPA,PPFIA3,ST3GAL5,GYG2,BAIAP3,CFAP410,HAP1,STOML1,AKAP7,AKAP5,SH2B1,OSBPL3,RASSF2,DAPK1,SPOCK3,CDON,SLC12A6,EDIL3,EGFR,PDLIM5,ADAM28,TDRKH,CNTRL,HLF,HNMT,IGF1,ITPKB,CDK18,PDE1C,MAPK10,ZDHHC14,RGS3,RPS6KA2,ZNF821,PKNOX2,PDZD2,WSCD1,DICER1,CHST8,CABIN1,SEMA3B" Drug 6906_UP STOCK1N-28457; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA1,NME5,APAF1,APLP1,APOC1,KSR1,SYNJ2,SCAPER,CA12,SEPT7,KIAA0586,DUSP9,ERCC2,IGSF6,TRMO,RUNDC3A,ZNF276,ATXN2L,DHX35,MIA2,MPP2,LYRM9,PPM1B,RELN,RGS12,EMID1,HUNK,MAPK12,SH3BGR,FBXO11,PREX2,LIMCH1,SNCA,KDM4B,TSNAXIP1,CLASP2,ZNF302,TMEM121,PARD3,PIK3R5,TPM1,XRCC4,PLSCR4" Drug 3800_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ALK,SEMA7A,KCNAB2,APC,CDK10,SEMA4G,RASL11B,SLC4A4,BMP7,CACNA2D2,EPS15L1,PICK1,CSNK1E,RIMS2,PARD6A,EXOG,DTNA,GNG4,HSF2,ITGA7,JAK2,LAMA2,NPR2,PPARA,MINDY2,KCTD17,PREX2,LIMS2,ARHGEF40,SLC9A5,ZNF334,ARHGAP26,LHPP,THSD1,ELOVL4,SYNE1,BHLHB9,TNS1,TRIO,VIPR2,KLC2,ZNF74,SH3GLB2" Drug 5269_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA1,LTBP4,SYT13,FAM131A,CDK13,ATP2A2,MTMR3,CACNA1I,CALB2,CAMK2B,RUNX1T1,TAOK2,CSF1,SEC14L5,SPOCK2,EGR3,DLL3,GCNT2,GRIK5,HLF,JAK2,KIT,MID1,NEFM,NPY,TMOD2,SERPINI1,CEP41,MAPK7,GDPD2,ZNF493,PKNOX2,FAIM2,IZUMO4,PHLDB1,SYT5,DMXL2,ZEB1,DOCK9,SLC35G2,CHST8,PIK3R5,VIPR2" Drug 5393_UP Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AGT,SEMA7A,CDC14B,ADGRB3,TPP1,SULT4A1,HEPH,DMPK,EDNRB,VPS13B,COQ7,GLYR1,RAB30,GNAO1,PCLO,CNTRL,LMO2,MYO7A,NFYA,NTRK2,LRP12,C19orf57,PPP5C,ZFHX4,TCP11L1,ZNF821,HKDC1,ARHGEF40,SMARCD3,MAPKBP1,ARHGAP26,IQSEC2,RBM26,RGL1,ARC,KIAA1107,ZNF34,UCHL1,FLRT2,NT5M,ST7,TIGD6,SENP7" Drug 7246_UP Etodolac [41340-25-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "APC,NRXN3,PLAA,HOMER3,ARMC8,CREM,SH2B1,NCOR1,LYPD1,CDON,EDIL3,TUBD1,ABCA8,ACSL4,FGFR1,TRMO,ERAP1,HTATSF1,BTN2A1,SYNPO,IRF8,TAGLN3,NF1,NRCAM,PFKFB2,MAPK7,WDR25,PTPN13,RGS4,MAPK12,WDR37,PPP4R3A,SS18,ELOVL4,SMG6,SZT2,CRTC1,ZNF34,TK2,R3HDM1,UGT8,KCNK12,ST7" Drug 3271_UP Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA2A,AGT,KIAA1324,APBB2,PPP4R4,CDK13,DNAH17,SLC2A11,LDLRAD4,CACNA2D1,CNTFR,CRMP1,TMCC2,DTNA,CNNM1,MBNL2,SCML2,FGF12,FYB1,GLYR1,STON1,GPER1,ITPKA,KCNN2,KCNQ3,MAN2A2,ADAM11,NF1,NOVA2,SMOX,ZCWPW1,KCTD17,TRA2B,RBM34,ARC,SYN2,PCDHGA10,ZNF34,CA14,VLDLR,WIPF1,ZNF74,ITM2C" Drug 3707_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "LTBP4,RASL11B,KIF1A,PROM1,CACNA1I,CFAP410,CD86,ARHGAP33,NDST3,RAB33A,AKAP6,RIMS2,DTNA,EGFR,AASS,LRRC17,EPHB1,ETV1,EYA1,ERAP1,GPD2,SOX21,PADI2,KCNJ5,MEF2C,ADAM22,NF1,PFKFB4,PLCB2,STRN3,PRKAR1B,PTN,ACSS3,NLGN1,LMO3,SSTR1,CUX2,TIAM1,R3HDM1,TNS1,CA14,FLRT2,LAT2" Drug 4810_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADD2,ADORA2A,NME5,KIAA1324,BIN1,APBA2,N4BP2L1,BAIAP3,CACNA1A,HAP1,CAPN3,RUNX1T1,EPS15L1,COL9A3,NRG2,NCOR2,VCAN,ELMO1,C2CD2L,DTNB,ELN,DLC1,AFF2,FYB1,GAD1,GLI2,GRIN2C,JAK2,KCNB1,KCNJ5,PACRG,AFDN,NOVA2,NPTX1,PPP5C,SUGCT,MRAS,CNKSR2,SLC11A1,ZC3H13,IQSEC2,GPR161,OSBP2" Drug 6421_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "RALGAPA1,ADORA2A,AP2A2,LTBP4,BIN1,APC,MARK4,ATP2A2,SCAPER,GYG2,ARHGEF1,CBFA2T2,RAB28,TPP1,SULT4A1,VCAN,CNTNAP2,SPOCK2,STX2,PDLIM5,CGREF1,INPP5K,ZNF276,KCNB1,KIF2A,NELL2,SLC11A2,MAPK7,GAL3ST4,RGS12,ZNF671,SLC12A4,SNCA,KDM4B,SPTB,DDN,LHPP,TBCEL,BHLHB9,R3HDM1,TNS1,OSBP2,LMF1" Drug 6328_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "CDC42BPA,DNAH17,BMP7,CACNA1G,CFAP410,LHX2,PICK1,AATK,CSNK1E,DTNA,FAM13A,PLXNC1,CORO2B,ST3GAL6,OGA,SEPT9,GFER,HTATSF1,PRUNE2,GUCY1A1,KCNB1,KIFC3,MGAT3,PDE4D,MINDY2,PTPRN2,C1orf54,RGS4,FRMPD1,PHLDB1,ASTN2,KIAA1107,WSCD1,DNAH7,THRA,TRIO,TSC2,TUBB1,VGF,VIPR2,VLDLR,XRCC4,KCNAB1" Drug 3357_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "OSBPL1A,APBB2,CFLAR,SOCS6,HOMER3,AKAP7,PDE4DIP,DZIP3,GIT2,MFAP3L,SEMA4D,FAM49B,ATP2C1,TRAF3IP2,USP19,MALT1,HNMT,HSF2,KHK,LSS,ZNF862,RETREG1,PLCD1,PRKAR1B,PRODH,TRAPPC13,SH3BGR,SH3BP2,ANKRD6,NUBPL,TMCC1,ZSWIM8,SPTAN1,TSPYL2,TROVE2,SS18,ELOVL4,MCF2L,FBXW11,RPGRIP1L,TK2,ZNF74,HPS4" Drug 454_UP cobalt(II) chloride hexahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ALCAM,AMPD3,GAS7,PPFIA3,PDE8B,SLC2A11,ATP6V0A1,CFLAR,KALRN,AP4M1,ARHGAP33,FOXN3,SLIT2,CNTFR,CDC42BPB,CRYM,AATK,PPP6R2,MBNL2,MRNIP,ELN,PIPOX,RASL12,IQCG,POMT1,ZNF276,PRUNE2,ADAMTS13,NXPH3,NCKAP1L,AFF1,FXYD7,SETD4,CEP41,TCP11L1,SEMA6D,ATXN2,ASAP3,AMBRA1,DOK5,CDK19,DMXL2,MARCH8" Drug 4354_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "FZD9,ADORA1,CDC14B,CDK13,ADAM23,NRP2,SCAPER,CACNA1G,RUNX1T1,CABP1,MYRIP,VCAN,HDAC9,SPOCK2,C3orf18,PDLIM5,FYB1,LPAR4,ATXN2L,IRF8,SHISAL1,KCNH2,KCNN1,TAGLN3,PCDH9,CEP41,MAPK7,SNRK,BAALC,RPS6KA2,RPS20,MRAS,SLA,ZSWIM8,ZNF423,ZC3H13,SYT5,SYNE1,R3HDM1,TRO,UCHL1,XRCC4,JPH3" Drug 5920_UP rotenone; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "MTUS1,KCNAB2,GYG2,BAIAP3,SYNGR3,MAGI1,CNOT8,STOML1,HAPLN1,CSF1R,PDE4DIP,SPOCK2,MFAP3L,RUSC2,DTNB,CELSR3,MRNIP,ST3GAL6,ZMYND10,MAP2,MAPT,ADAM22,NF1,NFYA,NPTX1,NTRK2,TREM2,GPR85,CNNM2,RGS4,RNASEL,GSTCD,LIMS2,ZNF334,TMCC1,KDM4B,SYT1,TLR4,TRIO,LAMP5,PCBP4,GAN,SENP7" Drug 5748_UP Butacaine [149-16-6]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ARSE,N4BP2L1,LDLRAD4,CACNA2D1,SLC16A4,LHX2,HOMER3,AKAP6,COL9A3,NCOR2,ABCG1,AATK,SPOCK3,DTNA,PLXNC1,NCALD,IGSF6,CDKL3,CORO2B,DLC1,FGF12,PRELID3A,SRCAP,GSTM5,SMAD1,TAGLN3,NF1,NTRK2,CDK18,PRKCB,MAPK7,PTN,ACSS3,RASA3,SH3BP2,DZIP1,SS18,SYN2,CUX2,R3HDM1,PIK3R5,TPM1,KCNAB1" Drug 5992_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "LTBP4,DOC2A,CDC42BPA,APBB2,SCAPER,PDE4DIP,DCAF4,TBC1D5,DBN1,DUSP9,EDNRA,HIPK3,EGFR,ING4,C3orf18,SPEG,NRN1,DLC1,CAMKK2,FYB1,SIGLEC8,ALDH1L1,HPGDS,GPD2,GRM8,ATXN2L,DHX35,NNAT,NKAIN1,TRIM68,ZFHX4,RASA3,ASAP3,KIF13A,TSNAXIP1,THSD1,WSCD1,PARD3,TNS1,CHST5,LAT2,KCNK12,JPH3" Drug 6098_UP Streptozotocin [18883-66-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADD2,ADRA1B,BIN1,SEMA4G,RGS20,BACH1,CFLAR,USP2,ARHGAP33,AKAP7,WHRN,SH2B1,IPCEF1,SLITRK5,BRINP1,KLHL3,DMD,HEYL,EFCAB2,PDLIM5,GCNT2,SRCAP,GRB10,SOX21,C2orf72,TJAP1,KCNN1,KIT,AFDN,MSR1,P2RY1,CDK18,LRP12,CCDC40,SUGCT,TCP11L1,HECW1,SPTAN1,SZT2,R3HDM1,UBE3A,SPHK2,GJC2" Drug 7396_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AP2A2,ADGRF5,AMT,SLC4A4,NRP2,CA4,KALRN,TAOK2,CRMP1,NCOR2,RIMS2,RIPOR2,EXOG,DTNA,HIPK3,ZNF391,ZNF549,FCGRT,FGF13,GFER,GPR75,GPD2,LPAR4,HNMT,IL12A,KCNJ5,MGAT3,WDR25,RIPOR1,NEK11,EMID1,SBF1,FUZ,SLC11A1,SNCA,SYN2,THRA,TK2,ZKSCAN5,KCNAB1,PARP11,EPM2A,UBE3B" Drug 2677_UP chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AMPH,OGT,PPP4R4,HIP1R,CHN2,CNN3,FAM149A,WHRN,CPS1,NCOR2,SUSD5,PDE4DIP,USP6NL,MFAP3L,SHANK1,DLC1,AGAP2,PDLIM5,GCK,GCNT2,GHR,GNAO1,STON1,MCHR1,CACFD1,BACH2,KCNF1,MMP16,NDP,DUSP26,PLCD1,CNNM2,SLC11A1,SNAP25,SOX15,SYN2,SYT5,CRTC1,PCDHA2,TPM1,TRIO,TRPS1,VSNL1" Drug 6285_UP Amoxicillin [26787-78-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,DOC2A,PPP4R4,MAGI1,CACNA2D2,SULT4A1,RAB26,COL9A3,CPS1,CRMP1,ABCG1,AATK,CSF1,SUSD5,DZIP3,RUSC2,COQ7,RRAGB,ST3GAL6,AFF2,GALC,TMEM8B,ZNF276,GNAL,IFI16,KCNB1,KCNN1,MX1,NOVA1,SAMD9,PTPRE,KHDRBS2,RGS4,CCDC88A,SNCA,ATP10B,PHLDB1,PCDHA5,TK2,VGF,LMF1,WIPF1,ZBTB14" Drug 5867_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF1,SEMA6A,APAF1,AZGP1,NRP2,BMP7,GYG2,NRXN3,QKI,RAB26,CNTFR,SLC4A8,CSF1R,TOM1,HSD17B14,VPS26C,REEP2,ERGIC3,GFER,GNAL,KCNN1,KHK,KPNA5,MAPT,AFDN,MYCN,CNOT4,SLC11A2,NTRK2,ENPP2,GPR85,SAMD9,RORB,NEK11,ASAP3,SLC4A3,TMCC1,PDZRN3,RBM34,CEP68,COBL,TK2,LMF1" Drug 6652_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ANK2,GAS7,PPP4R4,CDK13,AZGP1,KSR1,NCOR2,PDE4DIP,BRINP1,MYEF2,MFAP3L,SPOCK3,DTNA,RASGRP2,EPHB1,PIPOX,AFF2,RUNDC3A,LILRB4,AP4S1,SOX21,ATXN2L,ICA1,KCNB1,MSR1,NPY,PDE4B,GPR85,POU6F1,ENOX1,CRTAC1,PNMA8A,CCDC102B,TCP11L1,RXRA,FRMPD1,SNCA,ATP10B,KLHL4,DICER1,KCNAB1,FAM13C,NLRP3" Drug 1403_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG2,APBA2,CDK13,N4BP2L1,KRIT1,RAB26,C2CD2,CRYM,ARHGAP32,FEM1B,TMEM35A,EPB41L2,ERBB2,CDKL3,DISC1,SRCAP,PCDH17,GSTM5,PADI2,MAN1B1,KIF2A,MAP4,MMP17,GIT1,NFE2L2,NPY,RETREG1,PLCD1,RGS12,RNH1,CLIP1,SBF1,ZKSCAN3,DOK5,ZSWIM8,THSD1,LARP4,HEY1,CBX5,WBP2,WIPF1,TRIM9,MKRN3" Drug 6929_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,ASIC1,ADORA2A,AP2A2,KCNAB2,APBB2,CCNT1,CRLF1,PLAA,QKI,NCOR2,RGS6,ARHGEF10,DCAF4,PARD6A,CDON,TRMO,FYN,TJAP1,ITPKB,ADAM22,NOVA2,NPTX1,NPTX2,PRPH,FBXW7,EMID1,SBF1,SEC14L1,FBXO11,SLC22A4,KDM4C,CLASP2,ZC4H2,ARC,TNS1,PLPPR2,KCNK12,ZBTB14,SPHK2,UPF3A,MPPE1,ACTR3B" Drug 4984_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ABHD6,NDRG2,TRMT9B,APAF1,PPFIA3,MARK4,SLC4A4,ATP2A2,ADAM23,BAIAP3,CACNA2D2,HOMER3,CRMP1,SNCAIP,ARHGEF10,EXOG,ING4,SPEG,AGAP2,RUNDC3A,GPER1,GSN,IRF8,KCNH2,KCNJ5,KCNN1,KCNQ3,KIT,PPP5C,MAPK10,ZNF493,KCNIP1,SLC11A1,SNCA,TROVE2,PHLDB1,PCDHA5,CABIN1,CDK20,LMF1,WIPF1,LAT2,KCNK12" Drug 2385_UP Cortisone [53-06-5]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA1,SYT13,SEMA7A,APBB2,SPTBN4,ARRB1,PDE8B,ATP6V0A1,NRP2,GYG2,CFAP410,SULT4A1,AKAP6,CNTNAP2,DCAF4,SEC14L5,RIPOR2,EGFR,MTSS1L,HPCAL4,EFCAB2,PDLIM5,GAA,ERAP1,INPP5K,ALDH1L1,KCNMB4,MYCN,NOVA2,PFKFB2,MAPK7,PTN,CCDC40,PKNOX2,DOK5,DNMBP,PDLIM2,KIAA1107,TBCEL,CLIP2,LAT2,ZNF32,PLSCR4" Drug 258_DN LY294002; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG2,BRAP,ADORA1,AMPH,AQP6,EIF4G3,FUBP1,RAB29,CFAP410,SCARB1,CLCN3,HOMER3,PCYT1B,SH2B1,NCOR2,SIPA1L1,EXOG,DRP2,CALCRL,STX2,FGFR3,SCARA3,CAMKK2,MALT1,LILRA2,BTN2A1,IRF8,ITPKB,KCNQ3,MBP,MID1,MMP16,GIT1,CLDN11,FXYD1,HUNK,DZIP1,PKNOX2,CDK5RAP2,KDM4B,SPART,TBL1X,SSBP2" Drug 3485_DN Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG2,APC,FAM131A,APOC1,PPFIA3,BMP7,CFAP410,CRLF1,TAOK2,VAX2,SULT4A1,ABI3BP,BAG4,PDE4DIP,MFAP3L,DTNA,EZH1,FAM198B,MALT1,GNG4,LPAR4,KCNH2,KITLG,GIT1,SLC25A23,MAPK10,CCDC25,NEK11,SAFB,ZKSCAN3,LIMCH1,CDK19,ZBTB43,LHPP,CAMTA2,MGRN1,TNS2,ZNF34,PLPPR2,KLC2,KCNK12,ZNF45,MPPE1" Drug 6004_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ACHE,LTBP4,FAM135A,CDC42BPA,KCNAB2,ARHGDIG,PLA2G4C,BAIAP3,TBRG4,CACNA2D2,FAM189A2,QKI,WHRN,CSF1,VCAN,KLHL3,DMPK,EDNRA,C3orf18,VPS13B,ST3GAL6,FER,OGA,DISC1,SOX21,ATXN2L,TJAP1,INPP1,KIF5A,MAP2,MSI1,PAX6,LRP12,PPARA,RPS6KA2,SCN8A,BTBD7,DOP1A,VPS13A,RUNDC3B,TRPM2,UCHL1,EVI5" Drug 3744_DN Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "MTUS1,APC,APOC1,CDK13,STX16,SCAPER,PLEKHB1,FAM189A2,CNTN1,NCOR2,VCAN,ARHGAP24,CDON,DTNA,DUSP9,HIPK3,FAM13A,PLXNC1,FGF1,ANKFY1,PDLIM5,PRELID3A,KCNMB4,GRIK5,SCIN,MAN2A2,NPR2,STRN3,MINDY2,CEP41,PTCH1,SUSD4,GSTCD,MCMBP,FBXO11,PREX2,SLC9A5,TSNAXIP1,DOK5,CHST8,GPR161,TPM2,XRCC4" Drug 2808_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADRA1D,LTBP4,GAS7,SLC4A4,BMP7,BAIAP3,SLIT2,EPS15L1,AKAP7,WHRN,RIMS2,DCAF4,RUSC2,SHANK1,EIF4G2,ZNF589,FGF12,PRUNE2,GPER1,SPACA9,ADAMTS13,ICA1,KCNQ3,GIT1,CLDN11,PFKFB2,PLCD1,PLXNB1,PURG,NECAB2,SNRK,RASGRF1,ZDHHC14,RFX2,DZIP1,SLC2A5,PKNOX2,ARHGEF40,SNCA,KDM4B,SPTAN1,CABIN1,ITM2C" Drug 3265_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ABHD6,NDRG2,ADD2,GAS7,PDE8B,GYG2,HAP1,CBFA2T2,KCNAB3,TPP1,RUSC2,C2CD2L,TMCC2,SHANK1,HIPK3,MBNL2,TMEM35A,ALDH1L1,RUNDC3A,MSL3,LPAR4,CACFD1,LAMA2,MEIS2,CNOT4,SLC25A23,ELOVL2,TRIM68,SLC11A1,DOP1A,ZC3H13,LMO3,TROVE2,CAMTA2,SYNE1,GPR161,ZNF34,TNS1,TPM2,EMSY,DNALI1,ITM2C,KAT6A" Drug 3684_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,ADD2,LTBP4,BIN1,APAF1,ARRB2,SYNJ2,CBS,ARHGEF1,SEPT7,B4GALT6,AKAP7,SH2B1,NCOR2,DCAF8,CDON,DTNA,TRAF3IP2,SESN1,PCDH17,MSL3,POLL,CNTRL,KIFC3,ADAM22,NF1,OPRL1,PDE4D,PTN,PTPRB,CCDC40,ZCWPW1,RPS6KA2,ATXN2,MRAS,PREX2,ZNF667,ARHGAP26,SS18,VLDLR,ZBTB14,MAP3K12,TIGD6" Drug 4593_DN Ethionamide [536-33-4]; Down 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "APBB2,CDK10,CDK13,ADGRB2,CACNA1A,CBFA2T2,WHRN,PPP6R2,CDON,EDIL3,SCML2,BAIAP2,OGA,USP19,PRRC2B,ELOVL5,DHX35,INPP5B,MAPT,SCAMP5,MT1M,PPP5C,GRAMD1C,CNNM2,RIPOR1,PID1,CEP97,TCP11L1,MAPK12,ZNF821,DZIP1,ZNF334,ARHGAP26,ASTN2,CRTC1,TMEM121,SSBP2,VGF,VIPR2,LMF1,XRCC4,EVI5,KAT6A" Drug 2205_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA1,NME5,SRPX,FAM135A,BEGAIN,BIN1,DNAH17,BMP7,CAST,CCK,USP2,TAOK2,AKAP6,NRG2,CRY2,RIMS2,EDNRA,CDKL3,OLFM1,PRELID3A,INPP5K,PRUNE2,GSN,HAS2,ADAM22,PFKFB4,PLCD1,NECAB2,PPARA,PRKAR1B,RELN,PTPRN2,GAL3ST4,EMID1,PPM1E,CPEB3,TACR1,ADGRL3,WSCD1,ICAM5,MAP3K12,SLC17A7,PHTF2" Drug 5384_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "SYN3,ADRB2,CDC14B,CDK13,PDE8B,CFLAR,CAMK2G,CBFA2T2,AKAP5,NRG2,NCOR2,IPCEF1,SPOCK2,CDON,COQ7,RRAGB,FHL1,HPCAL4,PRELID3A,KHDRBS3,SRCAP,USP19,POLL,CNTRL,HLF,VSIG4,DHX35,MAP2,MID1,AFDN,NF1,CDK18,LRP12,LRRN3,PTPRH,TRIM68,FBXO11,PKNOX2,ATP10B,WSCD1,ZEB1,SLC30A3,JPH3" Drug 5543_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "RALGAPA1,TRMT9B,BIN1,CDC14B,ARRB2,DNAH17,MARK4,HAP1,KCNAB3,CLGN,COL9A3,RCHY1,CSF1R,CNTNAP2,RIMS2,DBT,SGSM2,DTNA,MBNL2,CDKL3,BAIAP2,FHL1,GSN,ICA1,IGF1,INPP5B,JAK2,KCNH2,IPO5,LIG4,MID1,NFYA,PDE4B,SLC25A23,POLG,SYBU,SLC11A1,STX1A,JMJD6,TRPM2,PLPPR2,NT5M,SEMA3B" Drug 1633_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AMPH,APC,APLP1,SEMA4G,PLA2G4C,DNAH17,MARK4,SLC4A4,ARHGEF7,CA12,B4GALT6,TAOK2,HOMER3,PHF20L1,EGR3,OGA,HNMT,ICA1,IL6ST,MGAT3,MPP2,PDPK1,PPP5C,ZCWPW1,GTDC1,RGS12,TCP11L1,RPS6KA2,SGK1,SH3BP2,SYBU,ANKRD6,KDM4C,NSFL1C,VPS13A,PLCB1,WSCD1,RPGRIP1L,DOCK9,KAT6B,VGF,HPS4,RNF170" Drug 5575_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF3,CDC42BPA,EPB41L5,APOC1,CDK10,ARRB1,CAMK2G,CAST,SLC4A8,BAG4,AKAP12,CSNK1E,FAM169A,PPP6R2,HDAC4,SGSM2,DMPK,STX2,ZNF589,FGFR3,MAP4,MIA2,RETREG1,FA2H,FSD1,PRKAR1B,FAM192A,SBF1,FBXO11,ABLIM3,PEX26,BTBD7,ZBTB43,ELOVL4,PHLDB1,COBL,TACC1,MCF2L,CABIN1,NPL,UBTF,LMF1,HPS4" Drug 1797_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "NDRG3,BRAP,ARNTL,STX16,ABI3BP,MATR3,ZNF804A,SPOCK3,DTNA,DUSP9,BAIAP2,SEMA4D,TRMO,SPIN1,HTATSF1,HNMT,NFYA,PIK3R1,ZFYVE21,MAPK3,CNTLN,FAT4,RBBP6,SUPT20H,SH3GL3,FNDC3A,SLC4A3,CCDC88A,DOK5,ARHGAP26,CLASP2,CEP68,VPS13A,SATB2,TNS2,TMEM121,METTL3,HIRA,BCL2L13,XRCC4,SPHK2,ZBTB38,AAAS" Drug 5433_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "C1QTNF1,AMPH,APOC1,RGS20,PTCH2,SULT4A1,GREB1,SPOCK3,DTNA,AASS,AGAP2,KHDRBS3,FYB1,ADAM28,PRUNE2,MAP4,MSR1,MYO7A,CNOT4,GRAMD1C,ELOVL2,PTPRB,FRMPD1,SLC2A5,FAM214B,CDK5RAP2,LIMCH1,PDZRN3,ZHX3,IZUMO4,SPTAN1,ATP10B,ZC4H2,ZEB1,SZT2,CRTC1,PCDHA5,ZKSCAN5,UBE3A,WIPF1,SLC30A3,NT5M,SLC17A7" Drug 988_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,ABHD6,C1QTNF3,ARNTL,PDE8B,SCAPER,SOCS6,SH2B1,ARMCX2,MFAP3L,EXOG,EGR3,ERCC2,FAM198B,ANKFY1,GALC,MSL3,POLL,HNMT,ICA1,IL6ST,INPP1,JAK2,MPP2,ADAM22,SLC25A23,TMEM104,RET,SGK1,SYBU,ANKRD6,CEP68,TTBK2,PLCB1,ADGRL3,FBXW11,TRIM2,RPGRIP1L,CABIN1,ZFP37,REEP1,MPPE1,EPM2A" Drug 6624_DN Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASIC1,TRMT9B,APBB2,APC,CDK13,DNAH17,KIF1A,MPDZ,CACNA1A,CBFA2T2,RAB28,SLC4A8,BAG4,CSF1R,CNTNAP2,CDON,TNK2,FGFR1,PDLIM5,FYB1,ZNF44,TRAF3IP2,DISC1,LPAR4,GRM8,AFDN,SLC11A2,PPARA,MAPK7,SAMD9,FAM184A,ZCWPW1,RPS6KA2,ATXN7,FBXO11,KDM4B,PDZD2,RPGRIP1L,TK2,TRIO,WIPF1,XRCC4,TIGD6" Drug 5430_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "RALGAPA1,ADD2,TRMT9B,GAS7,PPP4R4,PLA2G4C,N4BP2L1,NRP2,CFAP410,FOXN3,CHRNA4,AKAP7,DGKG,SPOCK3,HS3ST2,FAM13A,PLXNC1,RCAN2,ERCC2,APC2,CORO2B,SIGLEC8,SOX21,MSI1,NF1,TMOD2,PLTP,TRHDE,PTCH1,FBXW7,ZFP2,OGDHL,KDM4B,SPTAN1,SYT5,TCF4,SZT2,R3HDM1,UBE3A,UCHL1,OSBP2,XRCC4,AP3B2" Drug 4067_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADRA1D,SLC4A4,ADGRB2,NRP2,GYG2,CAMK2B,SCARB1,KCNAB3,CBARP,TAOK2,VAX2,CSF1R,RGS6,ARHGEF4,RIMS2,RIPOR2,DTNA,TENM1,ING4,ETV1,PIPOX,CSPG5,MCHR1,CACFD1,KCNN1,KIF5A,MARK1,MMP16,NF1,PCBP3,NTRK2,PTN,SH3BP2,ZNF334,KIF13A,IZUMO4,HECW1,ARHGAP26,PLCB1,AP4E1,CDK20,SPHK2,KCNAB1" Drug 7524_DN Suramin sodium salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,MTUS1,C1QTNF3,ALCAM,APLP1,ATP2A2,RIPK1,CFLAR,GYG2,CA4,ARHGEF1,NCOR2,LRIG1,DBT,DTNA,FGFR1,PRKAG2,FOXF2,ANKFY1,FAM49B,MAP4K5,MPP2,ADAM22,NFYA,NNAT,PLEC,PLTP,PPP3CC,PRPH,SBF1,TRA2B,PPP4R3A,KDM4C,UNC5B,CLASP2,ITPRID2,VPS13A,KIAA0930,PARD3,CHST5,VLDLR,ZNF24,EMSY" Drug 4210_DN Diflunisal [22494-42-4]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADCY6,TRMT9B,BIN1,PDE8B,DNAH17,ADAM23,CA12,IQCK,CSNK1E,VCAN,TBC1D5,DAPK3,ZNF589,ZNF44,TMEM8B,SEPT9,GNG4,LPAR4,GRM8,HNMT,INPP5B,JAK2,LMO2,PACRG,MGAT3,TAGLN3,SERPINI1,RETREG1,PLCD1,PLXNB1,BCAS3,PTPRB,FBXW7,ATXN7,ZNF821,GPR161,ZNF34,THRA,UGT8,ZNF711,NDRG4,EVI5,KCNAB1" Drug 6307_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASPHD1,ADD2,ADGRF5,APAF1,PPP4R4,CDK13,ZSCAN18,CFLAR,CACNA2D1,CAMK2B,ARHGEF1,SYNGR3,ARHGEF2,ARHGAP33,RCBTB2,PLEKHB1,CRMP1,AATK,RIMS2,ARMCX2,DTNA,CELSR3,EGFR,IRAK4,FGFR1,ZNF276,ADAMTS13,ICA1,KCTD15,POLG,SCN8A,ZNF821,ZFP30,PEX26,CCDC88A,ZHX3,ATP10B,OBSL1,CRTC1,AP4E1,TK2,ZKSCAN5,RPRM" Drug 4728_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASIC1,APBA2,CACNA1I,HAP1,CNOT8,RAB33A,PICK1,AATK,CSF1,SPOCK3,EDN1,RASGRP2,ERCC2,IGSF6,NSG1,GAD1,ALDH1L1,SRCAP,RUNDC3A,GPER1,SPACA9,ICA1,KCNH2,KHK,KIF5A,MAP4,AFDN,LYRM9,NELL2,CDK18,PPARA,PRODH,C1orf54,TCP11L1,EMID1,SH3GL3,SLC14A1,ARHGAP26,ATP10B,CRTC1,FLRT2,XRCC4,ITM2C" Drug 2882_UP Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ASIC1,AP2A2,PLA2G4C,GYG2,CACNA1I,CFAP410,CACNA1A,CAMK2B,CBFA2T2,ARHGAP33,CLGN,STOML1,ARHGEF6,SPOCK2,DTNA,EGFR,ERBB4,ERCC2,DLC1,AFF2,FAM49B,SRCAP,GPER1,SPACA9,HLF,ITGAM,NF1,PCBP3,TMOD2,SLC25A23,PRKCB,PTPRN2,KLHL11,ZFHX4,EMID1,KCNIP1,ZNF821,BTBD7,SNCA,SYNE1,PCDHA5,PCDHA3,SLC44A1" Drug 6640_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "AP2A2,AGT,TRMT9B,AMPD3,PPFIA4,LGR5,CACNA1I,BAIAP3,LDLRAD4,CHN2,CPS1,CSF1,BRINP1,CELSR3,MBNL2,TNK2,IGSF6,ZNF549,ETV1,LPAR4,INPP5B,LIFR,MATN3,MIA2,MYO6,PPARA,SNRK,RIPOR1,ZCWPW1,ZNF821,LIMS2,SNCA,ARHGAP26,DDN,ZEB1,TK2,ZKSCAN5,OSBP2,PLPPR2,ZNF711,NDRG4,FAM13C,SENP7" Drug 2094_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "BEGAIN,PPFIA4,SYNGR3,PLEKHB1,STOML1,CNR1,SH2B1,SEC14L5,MFAP3L,PLPPR4,HIPK3,PLEKHA1,ANKMY1,FGF1,BAIAP2,GNG4,CACFD1,ITGA7,MMP16,GIT1,MYO7A,NTRK2,PDE1C,PDE4D,WDR25,CNTLN,ELOVL2,SUSD4,GAL3ST4,RGS4,SH3BP2,SLA,PKNOX2,PHLDB1,CHST8,TIAM1,TK2,RPRM,VGF,REEP1,SH3GLB2,NT5M,SLC17A7" Drug 5476_UP Torsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "CDC42BPA,SEMA4G,ARRB1,NCOA1,ALDH7A1,NRP2,GYG2,LDLRAD4,HAP1,RCHY1,CSF1,CSF1R,VCAN,CNTNAP2,MED12,CALCRL,FGF1,FLNC,EFCAB2,PDLIM5,PRELID3A,FUT9,GCNT2,ADAM28,LYVE1,CACFD1,GUCY1B1,INPP5B,KIFC3,LAMA2,LMO2,SMAD1,MSR1,NPY,LRP12,RPS6KA2,KCNIP1,KDM4B,ZC3H13,SYN2,CRTC1,AMACR,SLC30A3" Drug 2406_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "PDE8B,KCNAB3,ZMYM4,SULT4A1,NCOR2,ABCG1,SEZ6L2,FCF1,MTSS1L,ERBB2,CDKL3,ERAP1,GATM,GCNT2,GNG4,FAM107A,ATXN2L,IFI16,KCNJ5,AFDN,MPP2,MYO7A,NELL2,NRCAM,WDR25,PTK2,GAL3ST4,RGS3,GALNT10,KDM4D,SNCA,KDM4C,PEG10,ATP10B,SYT1,MCF2L,TNS2,CRTC1,PCDHA5,ZNF34,FAM155A,LMF1,XRCC4" Drug 1470_UP Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-05 1.00E+00 4.75E-04 5.35E-03 43 199 "ADORA1,BIN1,CDC42BPA,APBB2,APLP1,ATP2B2,ATP6V0A1,GYG2,CAMK2B,TAOK2,RAB33A,QKI,HOMER3,DAPK3,DMPK,EDNRA,FGFR1,SEMA4D,GATM,GLYR1,POLL,GNAL,GPD2,GSTM5,HNMT,INPP5B,MYO7A,NNAT,PCBP3,RELN,CNTLN,PTCH1,PTH1R,SALL1,KIF13A,RBM34,ARC,IQCE,SZT2,CHST8,WIPF1,HPS4,DPF3" Drug CID000415676 NSC71948 Stitch 2.39E-05 1.00E+00 4.86E-04 5.48E-03 33 138 "ACHE,APAF1,APLP1,CA4,CACNA1A,CACNA1B,CNR1,HDAC9,DYNC1I1,ENO2,PPP1R1B,MSTN,PPARGC1A,TCERG1,PACSIN2,HP,IGF1,MAPT,NEFM,NEFH,OGG1,OPA1,ABCB1,PTX3,QDPR,FBXW7,ATXN7,FOXRED1,SNCA,SST,UBC,PRTFDC1,JPH3" Drug ctd:C035988 procymidone CTD 2.39E-05 1.00E+00 4.86E-04 5.48E-03 36 156 "ACTN1,DOC2A,DPP10,ATP2A2,NRP2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CAMK2B,CAMK2G,ASIC3,DBI,DPP6,EGFR,ERBB2,ERBB4,FYN,STMN2,GRIA2,MBP,NF1,NFIX,NRCAM,NTRK2,PDCD2,RELN,ROBO1,RXRA,HES6,NLGN1,UNC5B,STXBP1,SYP,TSC2,TUBA1A" Drug 4179_DN Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASPHD1,AMPD3,APC,CFLAR,CAMK2B,QKI,SNCAIP,DAPK3,TMCC2,DTNA,HIPK3,ING4,VPS13B,COQ7,ERCC2,ZNF589,OLFM1,CGREF1,SEPT9,GLYR1,MSL3,ADAMTS13,GSN,ICA1,KITLG,ADAM22,MX1,NF1,SERPINI1,MINDY2,PPP5C,PRKAR1B,KCNIP1,SLC2A5,IQSEC2,TROVE2,THSD1,SYT5,EXOC7,AP4E1,ZNF34,EPM2A" Drug 3562_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ABR,PKP4,CFLAR,KRIT1,BAG4,GIT2,DBT,FBXL5,LYPD1,DMPK,NR1D2,FCF1,PCYOX1,FAM49B,MAP4K5,HNMT,AGFG1,JAK2,IPO5,MAP4,NFYA,PIK3R1,PRKAB2,TMEM104,PTCH1,PTK2,SLC25A36,RNASEL,GSTCD,CLIP1,PPP4R3A,ZNF430,BTBD7,RBM34,ZBTB43,SS18,SYT1,ASTN2,TK2,TMPO,SSBP2,FIP1L1" Drug 5273_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "SPARCL1,ST3GAL5,CACNA1I,CFAP410,DLGAP1,CACNA2D2,FOXN3,SNCAIP,CSF1,SEC14L5,SPOCK2,PLXNC1,RASGRP2,NRN1,GAD1,GCNT2,GFER,PRUNE2,GRIK5,GSN,IL6ST,KCNJ5,MAP4,LRP1B,AFDN,MYT1,P2RY13,NTRK2,CDK18,PLCD1,PPARA,PTPRD,FAT4,ZNF821,SH3BP2,SLC2A5,ARHGEF40,SNCA,RGL1,SMG6,SLC44A1,CABIN1" Drug 5998_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "SEMA6A,AMPH,BIN1,GAS7,ARHGDIG,CACNA1G,BAIAP3,CACNB4,CAMK2A,FAM189A2,LY86,CRMP1,HIPK3,MBNL2,EGR3,TENM1,RASGRP2,FHL1,FLNC,PRELID3A,TPPP3,FYB1,FYN,SEPT9,SRCAP,PCDH17,RUNDC3A,NTRK2,PALM,MTRF1L,CRTAC1,RFX2,EMID1,ZNF821,RASA3,CNKSR2,TRIM2,GPR161,ZNF34,TRIO,ADAMTS9,TIGD6" Drug 6697_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "TRMT9B,AMT,CDC42BPA,KCNAB2,CDK10,MARCH3,SLC4A4,NRP2,ST3GAL5,FOXN3,CHN2,WHRN,CREM,NCOR2,ARHGEF4,ZFYVE16,DYNC1I1,FAM13A,AASS,COQ7,ETV1,SCML2,FGF13,AFF2,TDRKH,CNTRL,GUCY1B1,HNMT,TM6SF1,SCAMP5,NDP,SETD4,PPP5C,GRAMD1C,RPS6KA2,ASAP3,FBXO11,TK2,CBX5,LMF1,XRCC4,EMSY" Drug 1227_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASIC1,CDK10,ARNTL,N4BP2L1,SYNJ2,C5,IL33,LY86,AKAP7,AKAP12,CRY2,ZFYVE16,CELSR3,IRAK4,TNK2,ZNF276,STON1,GRIK5,GUCY1B1,ITPKB,ZNF862,NPR2,PRKAR1B,MARCH1,C1orf54,ZFP30,SH3BP2,BTBD7,SMARCD3,SPATA7,SPTB,SS18,EXOC7,TRIM2,SYNE1,CRTC1,TPM2,LAMP5,EMSY,HPS4,PLSCR4,TIGD6" Drug 7392_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "RALGAPA1,CLK4,PKP4,KCNAB2,APC,KYAT1,CBFA2T2,SCARB1,CACNA2D2,PLEKHB1,WHRN,CRY2,CTH,CNNM1,FAM13A,ETV1,RRAGB,RACK1,ATP2C1,ERAP1,ZNF276,GLYR1,GPER1,ATXN2L,TJAP1,CNOT4,CLDN11,SMIM7,MINDY2,PTPRE,TMEM231,FBXW7,CSRNP3,SUPT20H,ST6GAL1,TMCC1,SPTAN1,ST5,JMJD6,ZNF34,CABIN1,ZKSCAN5" Drug 7014_DN Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "OGT,CDC42BPA,APC,NCOA1,ADAM15,SYNJ1,LARGE1,QKI,KIAA0586,C2CD2L,PARD6A,SGSM2,EIF5,ERBB2,VPS26C,FGFR1,PDLIM5,CELF1,INPP5K,BTN2A1,PADI2,MAN2A2,MEIS1,NFYA,FSD1,C1orf109,REV3L,TCP11L1,SAFB,SEC14L1,SUPT20H,KIF16B,KDM4B,CEP68,DMXL2,SATB2,CABIN1,TSC2,CLDND1,MPPE1,FZD3,PHTF2" Drug 3347_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASIC1,ADORA1,AGT,NME5,ARHGDIG,BAIAP3,CFAP410,RUNX1T1,CACNA2D2,LHX2,TPP1,STOML1,NRG2,NCOR2,CSF1R,CNTNAP2,RUSC2,ERCC2,ZNF391,ZNF589,FHL1,DLL3,GCNT2,LYVE1,IL6ST,NF1,LRP12,CEP41,SAMD9,FAM184A,RPS6KA2,EMID1,SH3BP2,BTBD7,KDM4B,JMJD6,ARC,DOCK9,UBE3A,SLC30A3,SLC17A7,TIGD6" Drug 4503_UP Furosemide [54-31-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "AK2,PKP4,APAF1,CDK13,CFLAR,BMP7,WASF1,CNTN1,CNTNAP2,MYEF2,DTNA,ECM2,PLXNC1,EPB41,IGSF6,ETV1,DLC1,FGFR1,FAM49B,MSL3,GRIK5,CACFD1,ICA1,IRF8,KCNN1,SMAD1,MMP16,NPY,NLE1,STRN3,ELOVL2,RGS12,SNAP25,ZSWIM8,ARHGAP26,TROVE2,SMG6,CRTC1,ZFPM2,TNS1,TRIO,SPHK2" Drug 3973_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASIC1,NME5,APC,APLP1,APOC1,DNAH17,SLC4A4,CFAP410,CACNA1A,USP2,CBFA2T2,CNTFR,RCHY1,CPS1,CSF1,CNTNAP2,PPP6R2,DMPK,EDNRA,ANKMY1,ZNF589,FER,FHL1,SCARA3,CGREF1,SRCAP,GPER1,GRIK5,KCNJ5,MSR1,ZNF862,PLCD1,ZDHHC14,MSANTD2,RGS12,EPN2,TROVE2,THSD1,STX1A,CRTC1,WIPF1,ITM2C" Drug 7033_DN Thiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "NDRG2,SHROOM2,CDK10,ADAM15,CFLAR,STOML1,HOMER3,NCOR1,CSNK1E,TBC1D5,SGSM2,ANKMY1,F8,FYN,SYT17,MSL3,RNFT2,PADI2,DHX35,KHK,RETREG1,STRN3,PTPRG,NKAIN1,ROBO1,MAPK12,SYBU,EPN2,SIRT2,ZHX3,ZBTB43,CEP68,EXOC7,DNMBP,TRIM2,PCDHA6,RPRM,VGF,REEP1,GDPD5,MPPE1,RNF170" Drug 6485_DN Chrysin [480-40-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "MTUS1,CDC14B,MARCH3,KRIT1,LHX2,RAB28,AKAP12,FAM169A,GIT2,DBT,EXOG,STX2,FGFR3,BAIAP2,SYNCRIP,PDLIM5,MALT1,SLC2A6,HNMT,MAP4,PMP22,FA2H,PRKAR1B,PTCH1,RIPOR1,FERMT1,ELMO2,PDZRN3,ERC1,SPART,CLASP2,ELOVL4,JMJD6,MCF2L,ACTR6,BEX4,SSBP2,LMF1,ZIC1,REEP1,MARCH8,RNF170" Drug 5107_DN Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "APC,STX16,FUBP1,CACNA1A,SCARB1,TPP1,HAPLN1,DAPK3,BRINP1,CDON,EDIL3,FCF1,EGFR,IRAK4,CDKL3,ETV1,ZNF589,PDLIM5,SRCAP,GPER1,SHISAL1,KCNN1,KPNA5,MAPT,MT1M,NEK1,NFYA,CLDN11,STRN3,PPARA,BEND5,RGS4,ZNF671,SNCA,NXT2,ARHGEF9,TNS1,ZNF24,NT5M,EVI5,SLC17A7,SENP7" Drug 3715_UP Delcorine; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ADD2,EPB41L5,DNAH17,NRP2,BMP7,TAOK2,AKAP5,CREM,LRIG1,VCAN,DAPK1,SPOCK2,DMPK,DTNA,FCF1,SEMA3D,MBNL2,NCALD,ZNF549,KAT8,GPD2,SOX21,ATXN2L,KCNJ5,KCNQ3,ADAM22,NNAT,NPTX1,NTRK2,PDE4D,SEMA6D,RASA3,HKDC1,CNKSR2,RBM34,ZHX3,ZSWIM8,TRIM2,GPR161,UCHL1,WIPF1,KAT6A" Drug 4146_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASIC1,BIN1,AMT,CDC42BPA,ARRB1,RASL11B,CA4,B4GALT6,CRY2,SIPA1L1,TBC1D5,GIT2,TMCC2,DTNA,FCF1,EZH1,ZNF589,FGFR1,KHDRBS3,TRAF3IP2,SEPT9,GNG4,ATXN2L,JAK2,KCNH2,KCNN1,SMAD1,MATK,NEK1,NF1,RETREG1,MBOAT7,RIPOR1,RPS6KA2,KCNIP1,CLSTN2,PHLDB1,TBCEL,UCHL1,ZNF24,GDPD5,KAT6A" Drug 948_UP Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "C1QTNF3,CDC42BPA,APBB2,GAS7,PPFIA3,CDK13,MARCH3,GYG2,SCARB1,SRSF11,FOXN3,QKI,ENTPD4,CRY2,NCOR2,DZIP3,PHF14,GREB1,ARHGEF4,DCAF4,DTNA,FER,MSL3,GPD2,GRB10,SLC2A6,IRF8,MBD1,NF1,NPTX1,PCDH9,RNASEL,NEK11,AMBRA1,ANKRD6,PHLDB1,ASTN2,EXOC7,CRTC1,HIRA,MAP3K12,MPPE1" Drug 2482_UP Tolazamide [1156-19-0]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ADGRF5,ALK,CDC14B,CFAP410,TAOK2,RAB26,PCYT1B,WHRN,CABP1,COL9A3,ABI3BP,SNPH,DAPK3,FER,NBEA,KHDRBS3,GATM,GNAL,TDRKH,GRIK5,NCKAP1L,KCNN3,TAGLN3,MYO6,NPTX1,NTRK2,PRKAR1B,MAPK7,PRPH,WDR25,MARCH1,RGS3,TCP11L1,SEMA6D,STUM,CNKSR2,LIMS2,SLC11A1,ARHGAP26,TRIO,ZBTB38,SLC30A3" Drug 3086_UP Fluspirilen [1841-19-6]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "SYN3,ADD2,AMH,CDC14B,ATP6V0A1,BMP7,CACNA2D1,THSD7A,LARGE1,CACNA2D2,RAB33A,CNTN1,HAPLN1,BRINP1,CDON,C3orf18,ERBB2,ETV1,FGF1,FGFR1,PRELID3A,SIGLEC8,GPR75,PCLO,ELOVL5,MX1,MYO6,CDK18,PPP2R2B,CNNM2,ZCWPW1,RFX3,EMID1,SH3BP2,ASAP3,SLC11A1,SNAP25,FAIM2,CHST8,RPRM,VSNL1,DPF3" Drug 1331_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "AP2A2,SLC4A4,BCL7A,CFLAR,CAPN3,CD86,CLCN3,VCAN,DCAF8,TM9SF4,C2CD2L,RCAN1,EGR3,ANKFY1,ERAP1,INPP5K,VSIG4,IL6R,LIG4,MITF,CNOT4,OCRL,ENPP2,PIK3R1,ZFYVE21,RETREG1,PLEC,SAMD9,SGK1,SLA,SLC6A8,CCDC88A,SPP1,CDK19,SS18,UBE2H,PLPPR2,XRCC4,ZNF24,ATP6V0E2,LAMP5,HPS4" Drug 4583_UP Terconazole [67915-31-5]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ASPHD1,ABHD6,C1QTNF3,PPFIA4,APC,SYNJ1,MYRF,CAMK2B,KRIT1,ARHGEF2,CNTFR,AKAP7,CREM,CRY2,CTH,ING4,ETV1,REEP2,TRAF3IP2,TMEM8B,LYVE1,RUNDC3A,GLYR1,CNTRL,GRM2,PADI2,HNMT,JAK2,NPR2,PDE4D,PFKFB4,PTCH1,ENOX1,KIRREL1,SH3BP2,ST6GAL1,PKNOX2,NXT2,ZNF74,REEP1,SEMA3B,NAV3" Drug 5421_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "AK2,AMPD3,N4BP2L1,SYNJ2,MTMR3,CAMK2G,TAOK2,DTNA,DTNB,EDNRA,PLXNC1,VPS13B,SCML2,DLC1,FECH,FHL1,AGAP2,FYN,RAB30,PCLO,KIT,LRP12,PPP5C,VPS13C,PTPRE,RFX2,FERMT1,FBXO11,LIMCH1,SNCA,RBM34,DOK5,ATP10B,ASTN2,TBCEL,DMXL2,PIK3R5,TRIO,KCNK12,NT5M,ITM2C,RNF170" Drug 7364_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 4.86E-04 5.48E-03 42 193 "ADCY6,KCNAB2,MARK4,SCAPER,SOCS6,CNTFR,SLC4A8,DAPK3,EDIL3,OPTN,ELN,ZNF391,ETV1,EZH1,FDFT1,FGF13,ANKFY1,TRMO,GLYR1,PRUNE2,TDRKH,HMGCR,TJAP1,INPP5B,LMO2,KITLG,NF1,CLDN11,SERPINI1,PLCD1,PRPH,PTCH1,PTPRE,FAT4,ZDHHC14,SNCA,KDM4B,SPTAN1,ZKSCAN5,PDIA2,XRCC4,UBE3B" Drug ctd:C001277 geldanamycin CTD 2.46E-05 1.00E+00 4.98E-04 5.61E-03 69 371 "CLK4,OSBPL8,EPB41L5,CASK,CDK13,DST,HECTD1,RTTN,PDE4DIP,PYGO1,MATR3,ZC3H11A,PLPPR4,DMD,RCAN1,EDIL3,EDN1,SEMA3D,EGFR,MBNL2,ERBB2,FLT1,ARFIP1,CRCP,ZNF638,MAP4K5,RASSF8,AGFG1,IL6ST,KCNH2,MBNL1,MMP16,SAMD5,MYO5A,NF1,OXTR,PIK3R1,ZNF655,MAPK3,PTK2,PTPRD,ZFHX4,KIRREL1,CLIP1,SLC8A1,BDP1,SP4,PEG10,RBM26,TROVE2,ITPRID2,LARP4,DIP2A,PRRC2C,FRYL,TLR4,ERCC6L2,TP53BP1,NR2C2,TTC3,UBE2H,VLDLR,ZNF711,SLC38A1,EVI5,TUBA1A,KAT6A,PHTF2,JMJD1C" Drug 5233_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.49E-05 1.00E+00 5.02E-04 5.65E-03 41 187 "RALGAPA1,SPARCL1,APBB2,N4BP2L1,SYNJ1,ARHGAP33,DZIP3,GREB1,MBNL2,ING4,MRNIP,HSD17B14,PTK2B,POLL,STON1,GPER1,PCLO,TJAP1,LMO2,LYRM9,ZNF862,NF1,SERPINI1,PLCD1,SNRK,PTCH1,CARF,PCMTD2,TCP11L1,UHRF1BP1L,SPTB,IQSEC2,CEP68,PHLDB1,ARHGEF9,TACC1,PCDHGA10,THRA,PARD3,XRCC4,MARCH8" Drug 3677_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.49E-05 1.00E+00 5.02E-04 5.65E-03 41 187 "ARRB1,BMP7,CRLF1,TAOK2,RAB26,CREM,AKAP12,CSF1,CSNK1E,CTH,PITPNC1,HS3ST2,PLXNC1,EPHB1,IGSF6,ZNF391,ETV1,RASL12,AGAP2,FYB1,SIGLEC8,CSDC2,GNAL,GPD1,SCIN,ITPKA,MBNL1,TAGLN3,NPTX2,PDE4B,PDE4D,SMOX,FA2H,PPP2R2B,PID1,ATP10B,ADGRL3,TBL1X,PCDHA6,SPHK2,SEMA3B" Drug 7475_DN Trapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ASPHD1,AK2,BCAS1,CFLAR,ST3GAL5,C5,TAOK2,SMARCAL1,LRIG1,HDAC4,DAPK3,GIT2,FBXL5,COQ7,EZH1,CGREF1,GALC,MALT1,ZNF276,GRB10,HMGCL,KCNF1,LIG4,MEIS2,MYO9A,OGG1,PPP3CC,PRKAR1B,SUSD4,RGS12,RNASEL,FERMT1,FNDC3A,NUBPL,EPN2,ZBTB43,SS18,PHLDB1,CHST8,CABIN1,ZBTB14,MPPE1,ACTR3B" Drug 6740_DN Cyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ABHD6,SHROOM2,CDK10,MARK4,ATP1A3,SLC4A4,ADAM23,CAMK2G,ARHGEF1,RCBTB2,HOMER3,AKAP7,SLITRK5,DZIP3,DENND4A,ETV1,RRAGB,POLR1B,FYN,GLYR1,GPD2,GPER1,HNMT,SHISAL1,FAM69A,INPP5B,NDP,PRKAR1B,PRPH,APTX,CNTLN,PTN,SH3TC2,MRPS18A,SLC14A1,ZKSCAN3,SMARCD3,LIMCH1,CEP68,KIAA0930,ZKSCAN5,ZNF189,MPPE1" Drug 2323_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADORA1,AP2A2,APC,GAS7,ADAM23,ADAM15,AZGP1,CFLAR,CFAP410,LDB2,VAX2,CPS1,SNCAIP,RIPOR2,DUSP9,HIPK3,ELN,SPEG,ANKMY1,PTK2B,FGFR1,FHL1,NEU3,SRCAP,GPD1,TDRKH,GRM8,KIT,LSS,NF1,NNAT,PLCD1,C19orf57,PPARA,MAPK10,CCDC40,SLC6A8,CCDC88A,SPTB,TNS1,CHST5,DNALI1,ADAMTS9" Drug 6509_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AK2,SYT13,AMPD3,APBA2,RGS20,PTCH2,ADAM15,CA4,CAMK2B,RUNX1T1,CBLN1,MTMR7,SLIT2,AKAP7,WHRN,RCHY1,ARHGEF4,AASS,SRPK3,ST3GAL6,POLL,GNAL,GPER1,PCLO,ICA1,KPNA5,MATK,MBD1,MSI1,ENPP2,MTRF1L,PTCH1,RASGRF1,RGS3,PNMA8A,TCP11L1,SLC2A5,ZNF415,SLC44A1,TLR4,PIK3R5,VIPR2,ZNF711" Drug 7404_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ASPHD1,ABHD6,ADORA1,C1QTNF3,APBB2,PPP4R4,MPDZ,ST3GAL5,TPP1,FAM189A2,QKI,LY86,NECTIN3,CREM,CRY2,PPP6R2,JAKMIP2,HIPK3,BAIAP2,FHL1,PRELID3A,SYT17,ALDH1L1,GLI2,CACFD1,INPP1,KCNN1,MBD1,ADAM22,NNAT,CNOT4,NTRK3,MBOAT7,PRPH,ZSCAN2,SYBU,IQSEC2,SS18,ANKRD12,CDK20,VLDLR,ZBTB14,EPM2A" Drug 5781_DN Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADRA1D,SEMA4G,PDE8B,ATP2A2,ALDH7A1,CFLAR,C5,CAMK2B,QKI,CSNK1E,VCAN,CNTNAP2,SLITRK5,C2CD2L,KLHL3,TOM1,ING4,CDKL3,FCGRT,ANKFY1,DLL3,GAD1,ERAP1,MSL3,SHISAL1,KHK,MATN3,NEK1,NF1,NFIX,CNOT4,PPP5C,PTPRH,BEND5,ZNF671,FNDC3A,FAM214B,KDM4C,LHPP,TROVE2,LMF1,WNT7A,PHTF2" Drug 885_UP 5186223; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "BEGAIN,BIN1,DDO,CFLAR,RHBDL1,USP2,SLC16A4,ARHGEF6,COL9A3,HDAC4,DBT,MFAP3L,EXOG,DTNA,HIPK3,RRAGB,ZNF589,FGF1,FGFR3,PDLIM5,ADAM28,GPR37,FAM107A,AGFG1,TJAP1,ITGA7,KIF2A,MYCN,NPTX1,PLTP,RAD51D,RNASEL,NEK11,RASA3,CHD9,ANKRD6,EPN2,FAM214B,ZNF423,SPART,ASTN2,CHST8,TMPO" Drug 6403_UP valdecoxib; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADORA1,ADRA1D,KCNAB2,PDE8B,NRP2,SYNJ2,MTMR3,RAB33A,AKAP5,CRMP1,ARHGAP24,DAPK1,DBT,NCALD,ZNF391,SPEG,APC2,ETV1,FGF1,ADAMTS13,HLF,ICA1,MMP16,ADAM22,MYO7A,NELL2,PDE4A,PLCL1,LRP12,ELOVL2,TCP11L1,KCNIP1,SMPD3,PKNOX2,OGDHL,HECW1,CDK19,SPART,ARC,AMACR,TRPM2,CA14,SLC30A3" Drug 4489_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADCY6,ALK,DOC2A,AMT,IL33,CBFA2T2,FOXN3,CNOT8,LY86,PICK1,AKAP7,ABCG1,CSF1R,PPP6R2,SNPH,IRAK4,STX2,IQCG,TMEM8B,DISC1,INPP5K,ITPKA,MAPT,MBD1,MEF2C,ADAM22,PRKAR1B,MAPK7,GRAMD1C,TMEM231,PID1,ZCWPW1,NUDT11,SNCA,DDN,SYT1,TIAM1,R3HDM1,CABIN1,TNS1,TPM2,PLPPR2,NT5M" Drug 5494_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AGT,APBB2,MARK4,RASL11B,SLC16A4,CNOT8,TPP1,CNTN1,VCAN,MBNL2,STX2,CORO2B,ZNF589,FECH,FGFR1,TPK1,TXNL4A,TDRKH,RASSF8,IL6ST,KIF5A,LIG4,LMO2,MEF2C,TAGLN3,NTRK2,PTH1R,ZNF493,FBXW7,ABLIM3,SLC2A5,ARHGEF40,ELMO2,TACR1,CRTC1,TK2,HIRA,KCNK12,SLC30A3,MAP3K12,GDPD5,KCNAB1,EPM2A" Drug 3164_UP Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AMPH,ZSCAN18,AZGP1,NRP2,CAMK2B,CD38,B4GALT6,HAPLN1,RGS6,RIPOR2,ARHGAP24,JAKMIP2,C2CD2L,HEYL,CALCRL,FOXF2,GLI2,RAB30,GNAL,INPP5B,KCNB1,MEF2C,AFF1,AFDN,ADAM22,MYCN,TREM2,PLXNB1,PTX3,CCDC40,RASGRF1,KCTD17,CXXC4,ZSWIM8,IZUMO4,PLCB1,SYN2,PCDHGA10,RIMBP2,AMACR,CA14,ZNF45,NT5M" Drug 7436_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ABHD6,AK2,APBB2,APC,ARHGDIG,MPDZ,BAIAP3,CACNB4,QKI,ENTPD4,MFAP3L,EXOG,DNM1,HIPK3,EGFR,ENO2,MFSD10,NCALD,FHL1,B4GALNT1,ALDH1L1,MALT1,KCNH2,MBD1,SLC11A2,SETD4,PLCD1,STRN3,MBOAT7,PRKAR1B,WDR25,RGS12,SBF1,FRMPD1,LIMS2,IQSEC2,EXOC7,PCDHA5,ZNF34,BHLHB9,EVI5,MPPE1,IFT88" Drug 4170_UP Myricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "SEMA6A,APBA2,MARK4,ATP2B2,MTMR3,CACNA1I,CALB2,CBARP,CHRNA4,LHX2,AKAP7,CNTNAP2,DMPK,CDON,EDN1,FHL1,DCTN2,DISC1,GFER,RUNDC3A,HPGDS,KHK,MATK,MEF2C,NPY,NTRK2,NECAB2,PPP2R2B,MARCH1,RGS12,RNASE1,PNMA8A,SCN8A,STUM,KANSL3,SLC11A1,SMARCA4,PDZD2,ATP10B,JMJD6,SLC30A3,NT5M,ADAMTSL3" Drug 7170_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ASPHD1,PPFIA3,CDC14B,PLA2G4C,PDE8B,ALDH7A1,ADAM23,BCL7A,MAGI1,QKI,AKAP7,ARMC8,BAG4,HAPLN1,PDE4DIP,GIT2,JAKMIP2,LYPD1,COQ7,FHL1,TXNL4A,KCNMB4,HNMT,LIG4,MEIS2,ADAM22,NF1,NOVA2,SAMD9,PTPRH,NKAIN1,RGS12,KCTD17,DCUN1D2,GSTCD,PPP4R3A,CLASP2,WSCD1,TRIO,ZNF74,REEP1,MPPE1,SMIM8" Drug 2434_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADCY6,AGT,FAM135A,BEGAIN,BIN1,APBB2,MPDZ,SYNJ1,CALB2,CHN1,CHN2,STOML1,ABCG2,CSF1,ARHGEF4,PARD6A,SPOCK3,ELN,EIF1,DLC1,PDLIM5,TRAF3IP2,RUNDC3A,PCLO,GRIK5,ATXN2L,SYNPO,IL12A,KCNJ5,KIF5A,PLCD1,PPP2R2B,WDR25,PTN,RGS12,ZFHX4,MAP6D1,HECW1,ATP10B,KANK1,NSD1,TRIO,VGF" Drug 3759_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "MTUS1,APBA2,CFLAR,SYNJ1,SYNJ2,ARHGEF1,CBFA2T2,SOCS6,TPP1,CPS1,SLITRK5,DCAF4,GPRASP1,CDKL3,GLYR1,TDRKH,HSF2,SCIN,INPP5B,ITPKA,MAPT,MATN3,MX1,NF1,SERPINI1,PRKAR1B,MAPK3,PRPH,SH3BP2,DZIP1,SLC4A3,SNCA,LHPP,ATP10B,KIAA1107,KIAA0930,RPGRIP1L,CRTC1,TIAM1,TPM1,ZKSCAN5,VLDLR,SPHK2" Drug 4095_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AMH,ARRB2,PDE8B,ATP1A3,CBFA2T2,SCARB1,LY86,HOMER3,CNTFR,IQCK,AKAP5,AATK,PDE4DIP,RIMS2,BRINP1,MFAP3L,AASS,COQ7,ZNF589,FGFR1,FLT1,ATXN2L,KIFC3,MAPT,MIA2,TAGLN3,PDE4D,PLXNB1,PPARA,SNCA,TMCC1,KDM4C,TROVE2,MCF2L,PCDHGA10,PCDHA5,GPR161,TK2,TPM2,KLC2,XRCC4,NT5M,SEMA3B" Drug 3182_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AGT,ALK,AMPD3,KCNAB2,APLP1,CDC14B,CDK13,N4BP2L1,CHN2,SULT4A1,RIPOR2,BRINP1,EDNRB,C3orf18,LRRC17,DLC1,KHDRBS3,NSG1,DISC1,TDRKH,KCNB1,KCND1,MATN3,AFF1,ZNF862,MYT1,NF1,PLTP,POU6F1,PTN,RADX,GAL3ST4,SCN2B,PKNOX2,MYH15,PIK3R5,TRIO,TRO,WIPF1,ZNF45,NT5M,SEMA3B,ITM2C" Drug 1526_UP Midecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ASIC1,ABHD6,TRMT9B,AMT,APLP1,CDC14B,MARK4,CFLAR,SYNJ2,CFAP410,ARHGEF2,SEPT7,SOCS6,RAB33A,PLAA,FAM169A,RIMS2,HDAC4,MFAP3L,PIPOX,FGF12,INPP5K,MSL3,MCHR1,IL6ST,KCNJ5,NEK1,NF1,NOVA2,CLDN11,ELOVL2,PTN,C1orf54,SH3BP2,PPM1E,FERMT1,SLC6A8,RBM34,ERC1,ARHGAP26,SZT2,WIPF1,DPF3" Drug 6701_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "PKP4,APBB2,APC,SCAPER,IL33,KALRN,CACNA2D2,B4GALT6,TAOK2,CRMP1,HAPLN1,EXOG,DTNA,HIPK3,ZNF589,FGF1,EFCAB2,CAMKK2,ERGIC3,ATXN2L,ITPKA,PACRG,SMAD1,KITLG,MX1,CNOT4,NOVA2,OPRL1,PDE4A,PFKFB2,ELOVL2,RGS4,SH3BP2,SNCA,ZNF423,ARHGAP26,ASTN2,TAL1,PCDHA5,R3HDM1,TPM1,ZNF24,ZNF225" Drug 3398_UP Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "NDRG2,BEGAIN,KCNAB2,GYG2,CACNA1I,CAMK2B,PLEKHB1,RAB33A,COL9A3,DAPK3,RUSC2,ERCC2,PIPOX,F5,PTK2B,FGFR1,FHL1,DLL3,GDF9,GSN,HLF,TJAP1,MAN2A2,MEF2C,AFDN,MX1,NNAT,NPR2,NTRK3,PCDH8,GPR85,ZDHHC14,SBF1,ASAP3,HKDC1,ST6GAL1,OGDHL,KDM4B,JMJD6,SZT2,CHST5,TIGD6,SENP7" Drug 3664_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ASIC1,ACTN1,AMPD3,APAF1,APOC1,CBFA2T2,SEPT7,ARHGAP33,LARGE1,UBE2L6,FOXN3,CPS1,PDE4DIP,CDON,MBNL2,ING4,MRNIP,STX2,IQCG,PDLIM5,SRCAP,GPER1,SPACA9,IL6ST,INPP5B,KCNJ5,KHK,L1CAM,MAN2A2,MEIS1,NDP,CNOT4,NPR2,WDR25,SH3TC2,ENOX1,TCP11L1,LHPP,SS18,ASTN2,KIAA1107,LAT2,MPPE1" Drug 3549_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "CDC42BPA,SLC2A11,CACNA1I,USP2,MTMR7,DGKI,QKI,HOMER3,CNR1,RCHY1,IPCEF1,CNTNAP2,PPP6R2,MYEF2,CNNM1,LILRA2,GPER1,GRM8,TJAP1,KCNH2,KHK,MATN3,MGAT3,AFDN,ADAM22,NF1,PALM,ABCB1,PLCB2,NECAB2,SEPT4,PPP5C,CCDC40,PNMA8A,ZFP2,KDM4B,ATP10B,TBCEL,TCF4,OBSL1,TNS2,SLC17A7,SENP7" Drug 2134_DN Sparteine (-) [90-39-1]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ARNTL,SLC4A4,CAPN3,USP2,ARHGAP33,PLAA,TPP1,CSF1,SIPA1L1,VCAN,DZIP3,DGKG,ING4,PCOLCE2,ELN,RASGRP2,CDKL3,AFF2,KHDRBS3,ZNF44,SRCAP,DIDO1,FICD,ELOVL5,MYT1,NPR2,PLTP,PILRA,ZDHHC14,ZNF821,EPN2,SLC11A1,ZKSCAN3,MAPKBP1,KDM4B,IZUMO4,PDLIM2,SZT2,TPM1,PLPPR2,VIPR2,LAT2,XRCC4" Drug 5831_DN Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "ADRA1D,AK2,APBB2,CASK,CFLAR,SCAPER,WHRN,CSNK1E,VCAN,SLITRK5,ZFYVE16,SPOCK2,DBT,ERBB2,DENND4A,BAIAP2,SCARA3,FYN,GAD1,ERAP1,INPP5K,GCNT2,GSN,DHX35,NF1,PLCD1,LRP12,POLG,MAPK7,RGS4,ATXN7,COA1,UNC5B,TSPYL2,ARHGEF9,COBL,ZMAT3,METTL3,TRPM2,UBTF,LMF1,ZNF189,UPF3A" Drug 317_DN N-phenylanthranilic acid; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.64E-05 1.00E+00 5.26E-04 5.93E-03 43 200 "AMPH,APC,GAS7,ARNTL,ATP6V0A1,ARHGEF7,CD86,CD38,B4GALT6,ARHGEF6,SH2B1,CSF1,CSNK1E,DMD,DRP2,EDNRA,C3orf18,IQGAP2,GNAO1,GRM2,BTN2A1,MBD1,FXYD7,NOVA2,NTRK3,OPRL1,PPP2R2B,MTMR10,SH3TC2,RGS4,SLC9A5,CDK5RAP2,IFT122,TMCC1,IZUMO4,SPTAN1,CLSTN2,TEK,THRA,FLRT2,XRCC4,REEP1,MPPE1" Drug CID006857345 AC1OAGFB Stitch 2.67E-05 1.00E+00 5.33E-04 6.01E-03 93 540 "ASIC1,ADCY5,ADCY6,ADCY8,AP2A1,AP2A2,SPOP,AMPD3,AMPH,BIN1,SPTBN4,ARHGDIA,PLA2G4C,HCN2,SYNJ1,SYNJ2,BTK,CALM1,HIP1R,CCK,DGKI,ASIC3,EPS15L1,CLTC,AKAP5,PLCXD3,DGKB,DGKG,GIT2,SNAP91,DNM1,DNM1L,EDN1,EDN3,RASGRP1,EGFR,RASA4,EPB41,EPB41L2,RASGRP2,ERBB4,BAIAP2,AGAP2,AGAP3,SDCBP2,MALT1,GNAL,PLCD4,GSN,IGF1,SCIN,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNQ3,SYTL4,MATK,GIT1,OCRL,PDPK1,TMOD2,PIK3C2A,PIK3R1,PLCB2,PLCD1,PPP3CC,PRKCB,PTK2,RASGRF1,RDX,GSTCD,KCNIP1,SCN7A,RASA3,ASAP3,SLA,SLC8A1,ARFGAP1,FNBP1,SPTAN1,SPTB,NSFL1C,PLCB1,SYT1,MLST8,EXOC7,TBL1X,ICAM5,ACTR6,UBC,VAV1,PLD4" Drug 3274_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "MTUS1,RIPK1,CFLAR,ST3GAL5,SYNJ2,SCAPER,QKI,NCOR1,GREB1,GPRASP1,NR1D2,FEM1B,FCF1,IRAK4,EXTL2,EZH1,FECH,BAIAP2,CINP,SEPT9,ARFIP1,GPR37,GSN,MPP2,NFYA,SLC25A23,PRKACB,SLC25A36,SAFB,ZNF821,SGK1,SH3BGR,RCOR3,MAPKBP1,SS18,TBL1X,TPM1,HIRA,XRCC4,MPPE1,EPM2A,RNF170" Drug 6964_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "AK2,CDC42BPA,ADAM15,SYNJ2,CCNT1,CNOT8,RAB28,HOMER3,CREM,SOCS5,DCAF8,C2CD2L,MRNIP,VPS26C,F8,PDLIM5,TRAF3IP2,INPP5K,GPD2,RNFT2,HSF2,NEK1,NFYA,CCSER2,RETREG1,KCTD15,SLC25A23,FSD1,CCDC25,TRAPPC13,AMBRA1,SOX3,TSPYL2,SS18,ARHGEF9,EXOC7,SATB2,BHLHB9,SSBP2,MAP3K12,RNF170,GAN" Drug 4709_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "NME5,SPARCL1,APC,APLP1,CDK13,CFLAR,GYG2,CAMK2B,MAGI1,TAOK2,CRMP1,VCAN,MAML1,SPOCK2,GIT2,FCF1,EPHB1,FGFR1,FHL1,ANKFY1,GALC,SIGLEC8,USP19,GLYR1,STON1,ATXN2L,LAMA2,PACRG,MAN2A2,AFDN,MMP16,OPRL1,PGAM2,STRN3,CCDC40,ZNF821,TRA2B,SAMSN1,DMXL2,CRTC1,PCDHA6,PHTF2" Drug 4126_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ADRA1D,LTBP4,BIN1,APBA2,FAM131A,CDC14B,BMP7,CACNA1I,CAMK2G,CLGN,TAOK2,PLAA,STOML1,ING4,ENO2,DLC1,IQCG,GAD1,INPP5K,SRCAP,PCLO,CACFD1,GRM8,IL6ST,INPP5B,IPO5,LSS,NLE1,SAMD9,RGS12,RPS6KA2,ASAP3,ABLIM3,SLC6A8,BTBD7,SNCA,DOK5,IQCE,KIAA0930,TNS2,TFIP11,PHTF2" Drug 3716_UP Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ASPHD1,LTBP4,SEMA7A,BCAS1,SLC2A11,CA12,ARHGAP33,TAOK2,CLTB,SULT4A1,CRY2,CSF1,DAPK3,HS3ST2,DTNA,DUSP9,HEYL,CDKL3,FYB1,ZNF44,B4GALNT1,GNAL,GRIN2C,KCNN2,KCNQ3,NPTX1,PALM,PCDH9,PPARA,PBRM1,PEX26,ZSWIM8,NFASC,ARC,SYT5,TAL1,DMXL2,SLC44A1,TNS1,CDK20,LAT2,REEP1" Drug 5776_DN Hexestrol [84-16-2]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ADCY6,BIN1,PPFIA3,MARCH3,NUMB,ALDH7A1,SYNJ2,SCAPER,CHN2,PLEKHB1,HAPLN1,CSF1,CNTNAP2,ARHGAP24,ZFYVE16,GIT2,DBT,RHOBTB1,TMCC2,FEM1B,ETV1,FGF13,AHDC1,GUCY1B1,KIF2A,CLDN11,FSD1,PTN,PTPRN2,TMEM231,RPS6KA2,ASAP3,LIMCH1,ELOVL4,CEP68,PHLDB1,JMJD6,HIRA,UGT8,WNT7A,NDRG4,KCNAB1" Drug 3604_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "LTBP4,AMT,APBB2,STX16,ALDH7A1,SYNJ2,CA4,CAMK2G,CBFA2T2,CLCN3,PDE4DIP,ARHGEF4,KIAA0586,EXOG,HIPK3,PHF20L1,SUGP2,ENO2,COQ7,ZNF589,ALDH1L1,USP19,PADI2,ICA1,KPNA5,MIA2,LYRM9,NF1,PLCD1,FSD1,WDR25,GSTCD,PPP4R3A,BTBD7,COA1,CDK5RAP2,SNCA,KDM4C,IQSEC2,CLSTN2,TBCEL,SLC44A1" Drug 3846_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ADD2,APOC1,PPP4R4,PLA2G4C,STX16,MTMR3,RUNX1T1,CLGN,LHX2,NCOR2,GREB1,DAPK3,DMD,HS3ST2,TSPAN5,ERBB2,SPEG,CORO2B,PDLIM5,CAMKK2,SRCAP,GLYR1,GSN,IL6ST,LSS,KITLG,MMP16,GIT1,MX1,TMOD2,PRKAR1B,MAPK10,RAD51D,RGS12,SCN8A,ST6GAL1,PPP4R3A,ZBTB43,CHST5,UBE3A,NT5M,PHTF2" Drug 6794_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ALCAM,APC,EPB41L5,BCAS1,SLC4A4,ALDH7A1,CFLAR,GYG2,SLIT2,RCHY1,ENTPD4,PDE4DIP,MFAP3L,EDNRA,CDKL3,FGFR1,OGA,ZNF276,TXNL4A,MSL3,FERMT2,BTN2A1,MATK,GIT1,NEK1,NNAT,POLG,GTDC1,RGS3,RPS6KA2,SBF1,SH3BP2,FNDC3A,BTBD7,SPART,SS18,TTBK2,PHLDB1,TBL1X,KIAA0930,MAP3K12,PHTF2" Drug 4488_DN Amrinone [60719-84-8]; Down 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ALK,DOC2A,APLP1,CDK10,ADGRB2,CFLAR,SCAPER,MYRF,FOXN3,AKAP7,WHRN,ABCG1,DTNA,TNK2,FGF1,FGFR1,FAM49B,DENND2A,SYT17,POLL,MAPT,CLIP1,SH3BP2,ASAP3,LIMS2,FAM214B,CCDC88A,SLC9A5,ZNF667,COA1,MYH15,KDM4B,SPTAN1,SPTB,JMJD6,ASTN2,SYNE1,GPR161,TNS1,HIRA,LAT2,SEMA3B" Drug 4163_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "NDRG2,NME5,C1QTNF3,EPB41L5,SYNJ2,CBFA2T2,CACNA2D2,QKI,HOMER3,SIPA1L1,DZIP3,DBT,MFAP3L,DTNA,ING4,DLC1,FGFR1,SEPT9,SPIN1,MSL3,GNG4,GPD2,INPP5B,KCNF1,NPTX1,LRP12,MBOAT7,PRKAR1B,GRAMD1C,MSANTD2,AP1AR,DOK5,CLSTN2,TACC1,EXOC7,PCDHA6,DICER1,AP4E1,TMPO,PARD3,FAM155A,UCHL1" Drug 3906_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "APAF1,APC,ARHGDIG,MYRF,CACNA2D1,RCBTB2,ARHGEF6,CNTFR,CABP1,SEC14L5,SPOCK3,CDON,DTNB,FGFR1,KHDRBS3,FYN,PRUNE2,PCLO,TJAP1,KIT,LMO2,LSS,ZNF862,NINJ2,NNAT,NOVA2,CLDN11,PDE4B,SERPINI1,PLCD1,PTPRH,TRIM68,RPS6KA2,SCN8A,ELOVL4,PIK3R5,TRO,CA14,LAT2,EMSY,NT5M,KAT6A" Drug 4642_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ADCY6,AP2A2,BEGAIN,CDK10,SOCS6,RAB28,STOML1,QKI,CREM,CSF1,CNTNAP2,DBT,C2CD2L,EXOG,EDNRA,EIF5,VPS26C,PDLIM5,FYB1,FYN,SYT17,STON1,GPER1,ITPKA,NEFM,NPTX1,PDE4D,RETREG1,SNRK,PTK2,TMEM231,CLIP1,FNDC3A,KANSL3,SLC14A1,ARHGAP26,PHLDB1,COBL,TNS1,SSBP2,ZNF32,EPM2A" Drug 6173_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.74E-05 1.00E+00 5.43E-04 6.11E-03 42 194 "ASIC1,APBB2,PLA2G4C,PDE8B,ATP1A3,SLC4A4,SULT4A1,FAM149A,SLITRK5,RIPOR2,DNM1,TNK2,C3orf18,MTSS1L,ERBB2,FGFR1,BAIAP2,SEPT9,GNAO1,GRM8,GUCY1A1,PADI2,KCNF1,MYO7A,NEFM,NTRK2,OPRL1,EMID1,SATB1,GALNT10,KDM4B,ZNF423,NFASC,SYT1,TRIM2,HIF3A,SLC44A1,TK2,OSBP2,CLIP2,TRIM9,ADAMTSL3" Drug CID000002802 clonazepam Stitch 2.80E-05 1.00E+00 5.54E-04 6.24E-03 23 82 "ATP1A3,SGCE,CACNA2D1,CBR1,CCK,DBI,GPHN,ZMYND10,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,LOXL3,KCNQ3,CNTN3,FXYD1,PTCH1,ARX,SLC4A3,ARHGEF9,ZEB1,EPM2A" Drug 1150_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.83E-05 1.00E+00 5.61E-04 6.32E-03 41 188 "ABHD6,MTUS1,APBB2,PPP4R4,ARNTL,NCOA1,ST3GAL5,CAST,CDO1,CHN2,PDE4DIP,SLITRK5,PPP1R16B,DOCK4,ZFYVE16,KIAA0753,DTNA,FAM13A,CDKL3,EXTL2,PCYOX1,PADI2,ITGA7,MAP4,MITF,PTCH1,RPS6KA2,SATB1,ANKRD6,FAM214B,TMCC1,RGL1,STXBP1,PJA1,DNMBP,TCF4,ZEB1,TPM1,NPDC1,GDPD5,FZD3" Drug 5958_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.83E-05 1.00E+00 5.61E-04 6.32E-03 41 188 "ASIC1,ADCY6,AK2,APAF1,GAS7,CFLAR,SEPT7,TAOK2,LHX2,STOML1,HOMER3,PICK1,AKAP7,CSF1R,VCAN,CNTNAP2,SLITRK5,FAM131B,GAD1,DISC1,TDRKH,KIFC3,ZNF862,NPR2,SLC11A2,PALM,PLXNB1,SAFB,ARHGEF40,RBM34,TROVE2,COBL,PDLIM2,TCF4,TNS2,CRTC1,OSBP2,LAT2,ZNF711,TRIM9,TFIP11" Drug 3227_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.93E-05 1.00E+00 5.78E-04 6.51E-03 40 182 "NME5,CDC14B,BMP7,ST3GAL5,CLGN,WHRN,ARMCX2,JAKMIP2,TSPAN5,OPTN,IQCG,FYN,CYP46A1,RAB40B,STON1,MXI1,NEK1,SERPINI1,PMP22,GRAMD1C,PRPH,GAL3ST4,RPS6KA2,SH3BGR,SH3GL3,PPM1E,ASAP3,WDR47,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SSBP2,LAT2,ZNF45,SLC30A3,GDPD5,SLC17A7" Drug 3740_UP Gossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-05 1.00E+00 5.78E-04 6.51E-03 40 182 "ADRA1D,OGT,PPP4R4,RASL11B,BMP7,SYNJ1,CARS,CBS,ARHGEF2,EPS15L1,RCAN1,ECM2,FRY,CELSR3,EGFR,MBNL2,ENO2,POLL,FERMT2,MARK1,MIA2,MMP16,NF1,NFYA,CLDN11,PDE4D,PFKFB3,PFKFB4,PTPRB,PTX3,BEND5,ZNF821,HECW1,ARC,CRTC1,TK2,CA14,VLDLR,XRCC4,SPHK2" Drug 7043_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.93E-05 1.00E+00 5.78E-04 6.51E-03 40 182 "NME5,APLP1,ARNTL,BMP7,ST3GAL5,BAIAP3,SPAG9,CLGN,PDE4DIP,DOCK4,TMCC2,OPTN,ACSL4,FHL1,FYN,CYP46A1,RAB40B,TDRKH,STON1,SLC2A6,MITF,PCDH9,SERPINI1,GRAMD1C,PRPH,RPS6KA2,SH3GL3,WDR47,PKNOX2,ELOVL4,RGL1,STXBP1,KIAA0930,RPGRIP1L,HEY1,BEX4,NPL,RUNDC3B,SLC30A3,SLC17A7" Drug ctd:D014415 Tunicamycin CTD 2.98E-05 1.00E+00 5.88E-04 6.62E-03 230 1577 "PTCHD1,BEND6,KLHL13,AGT,OSBPL6,AK2,SRPX,MARCH4,BEGAIN,AMT,ANK2,PPFIA4,APOC2,ARRB1,PDE8B,ASGR1,RASL11B,TMEM108,SLC4A4,ATP2A2,ALDH7A1,N4BP2L1,ATP6V1G2,ATP6V0A1,ADAM23,SEC11C,RGS11,BCS1L,BID,GPR146,CFLAR,ST3GAL5,GPC2,CALM1,SLC25A14,CARS,RUNX1T1,PRC1,ARHGEF2,CDH2,CDO1,CCPG1,CACNA2D2,COPB2,CBARP,SLIT2,CNN3,CABP1,COL4A5,LETMD1,VCAN,PPP1R16B,CTH,BRINP1,DBI,DBT,DYNC1I1,NR1D2,DMTF1,E2F5,EBF1,EDIL3,ASB3,EIF5,PCOLCE2,TMEM35A,EIF1,ENO2,COQ7,NCALD,CDKL3,ARMCX1,TBC1D16,TUBA1B,TUBB3,FDFT1,GORAB,FECH,PRKAG2,ATP5PD,SEC23B,SYNCRIP,FLT1,TMEM175,WDR83,UFM1,CGREF1,DLL3,GALC,MTHFD2,SYT17,GATM,MMADHC,PPARGC1A,ZNF638,LOXL3,GNG4,GPT2,SPACA9,GRM2,KAT7,FICD,LINGO1,RNFT2,GUCY1A1,SLC2A6,PACSIN2,ACOT7,HMGCL,HMGCR,CPT1C,HSPA1L,SMAP1,IDH3A,IGF1,DISP2,IL12A,INPP1,INPP5B,ITGAM,KCNJ16,STMN1,SFXN5,LSS,MEIS1,MMP17,DBNL,COMMD5,BLOC1S2,TAGLN3,MYCN,HNRNPM,NCAM2,NEFH,NFE2L2,NNAT,NME4,DNHD1,NPTX2,NRCAM,NUCB2,PCDH9,PDE4B,PDE4D,ENPP2,GPR85,GNG2,PFKFB3,PFKFB4,DUSP26,PIK3R1,SNX10,PKM,KCTD15,GPSM2,SLC25A23,PCDH18,POLR2F,PPARA,PPP2R2B,PPP2R5E,PPP3CA,VSTM2L,PKIA,MAPK3,MAPK9,LAMA1,WDR25,PTPRH,QDPR,RET,PRRT2,RGS4,NUDT11,TMLHE,CYB561D1,MRAP2,SPIN3,RTN1,RMI1,DGLUCY,SARS,HES6,TNFRSF19,PPM1E,CPEB3,SHMT2,SEC31A,SLC8A1,ABTB1,SMARCA4,RCOR3,SNAP25,FAIM2,GLT8D1,ZNF423,LMO3,ZNF621,ERBIN,MPRIP,STAC2,SYPL1,ANKRD12,FBXW11,TCF4,PCDHB9,PCDHB3,VWCE,DICER1,ZMAT3,ZNF34,ZNF106,CDH22,HEY1,PDSS1,PDIA2,VGF,VIPR2,TBC1D15,KCNK12,KCNT2,POLR3H,ZNF195,LAMP5,STOX2,TUBA1A,ADAMTS9,NETO2,SOCS4,ST8SIA2" Drug CID000005114 3-(1H-pyrrole-2-carboxylate Stitch 3.01E-05 1.00E+00 5.94E-04 6.69E-03 48 233 "SLC24A4,AK2,ANK2,ATP2A2,ATP2B2,ALDH7A1,CACNA1A,CACNA1B,CACNA2D1,CALM1,CAMK2B,CCK,KRIT1,CD38,LRBA,HOMER3,AKAP6,CABP1,AKAP5,MYEF2,DMD,EDN1,EDN3,EDNRA,SPSB4,SCARA3,CAMKK2,ATP2C1,GCNT2,KCNMB4,GRIA2,GRM2,GRM8,GUCY1B1,KCND2,KCNH2,KCNN3,NPR2,PPP3CA,PPP3CC,PRKACB,PRKCB,QDPR,RYR3,SLC8A1,SNAP25,CABIN1,TRPM2" Drug 5416_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "CDC42BPA,PPFIA3,PPP4R4,ATP6V0A1,FOXN3,TAOK2,CRY2,PPP6R2,C2CD2L,CELSR3,ING4,HSD17B14,FGFR1,BAIAP2,FHL1,DISC1,GPER1,GRIK5,HNMT,IL6ST,KCNF1,MMP16,NPTX1,KCTD15,SMIM7,PRKAR1B,ELOVL2,GTDC1,RGS3,RGS12,NEK11,SBF1,ABLIM3,THSD1,STX1A,NSFL1C,ASTN2,MCF2L,TMEM121,CHST8,PLPPR2,ZNF74" Drug 4322_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "LTBP4,PPFIA4,CDK10,CDK13,FUBP1,CBS,RCBTB2,ARHGAP22,CLTB,CNTN1,WHRN,CSNK1E,INTS1,MAML1,C2CD2L,SPOCK3,SGSM2,DTNA,ABCA8,TRAF3IP2,ADAM28,GPER1,GRIK5,SYNPO,ICA1,CDK18,PFKFB4,MAPKAP1,RGS4,FBXW7,SEMA6D,ASAP3,ST6GAL1,ANKRD6,SMARCA4,KDM4B,IQSEC2,PHLDB1,ARHGEF9,SZT2,GPR161,LAT2" Drug 7372_UP Ofloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ADCY6,NME5,MADD,MTMR3,TAOK2,NCOR2,RUSC2,EXOG,DTNA,DUSP9,MBNL2,IRAK4,MRNIP,COQ7,F5,FER,FGF1,FGFR1,ANKFY1,MSL3,CNTRL,DHX35,TJAP1,IL12A,FAM69A,ITPKA,NOVA2,APTX,KCTD17,EMID1,TRAPPC13,ST6GAL1,SLC4A3,SPTAN1,IQSEC2,DDN,ST5,SMG6,TMEM121,TLR4,UBE3B,KAT6A" Drug 2089_UP Piroxicam [36322-90-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,OGT,STX16,BACH1,RAB28,ABCG2,QKI,DCAF4,SNPH,DAPK3,DBT,MFAP3L,HIPK3,ETV1,TAOK3,SCML2,FGFR1,HPCAL4,SESN1,GLI2,STON1,GSTM5,HSF2,ICA1,INPP5B,MATN3,GIT1,NEK1,CNOT4,PIK3R1,STRN3,MINDY2,BCAS3,GAL3ST4,KIRREL1,ZBTB43,TBL1X,ICAM5,TMPO,TST,ZKSCAN5,XRCC4" Drug 7219_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,AGT,AK2,LTBP4,CDC42BPA,APBA2,LDLRAD4,CAMK2B,RCBTB2,TAOK2,NECTIN3,HAPLN1,NCOR2,MFAP3L,RASGRP2,AGAP2,FYB1,ERAP1,SRCAP,GFER,SPACA9,HNMT,KCNJ5,LSS,PACRG,KITLG,MITF,ADAM22,MYO7A,NEFM,CNOT4,NLE1,SLC25A23,PLTP,RGS12,SLC11A1,PHLDB1,SYT5,TACR1,PCDHA6,SLC44A1,GDPD5" Drug 5051_DN Roxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "APC,APLP1,LGR5,MARCH3,SLC4A4,EIF4G3,SOCS6,AKAP7,IQCK,NRG2,CSF1R,VCAN,SLITRK5,SPATA2,RCAN1,FAM13A,EGFR,ZNF589,SCARA3,FYN,INPP5K,COPS8,GPER1,JAK2,NPR2,MAPK7,CNNM2,ZDHHC14,FBXO11,DZIP1,FAM214B,ZNF667,TROVE2,SS18,NXT2,CEP68,JMJD6,GPR161,TK2,TRIO,OSBP2,SPHK2" Drug 3476_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASPHD1,ABHD6,ADRA1D,ALCAM,DOC2A,CDC42BPA,FAM131A,APOC1,MARCH3,TAOK2,MFAP3L,MAMLD1,CELSR3,EIF5,ANKMY1,BAIAP2,CGREF1,DISC1,GNG4,LPAR4,PADI2,HNMT,ITPKB,KHK,LYRM9,NEK1,NPR2,RETREG1,NLE1,SLC25A23,MBOAT7,NEK11,EPN2,MAPKBP1,SPART,THSD1,ANKRD12,PARD3,ZKSCAN5,KLC2,REEP1,ACTR3B" Drug 6006_UP Nifedipine [21829-25-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "C1QTNF1,LTBP4,BIN1,APAF1,ARHGDIG,CDK13,MARK4,CACNA1I,CAMK2B,CAST,OSBPL3,MAML1,DMPK,HS3ST2,EDN3,RASGRP2,PIPOX,NRN1,CAMKK2,OGA,GATM,NEU3,ALDH1L1,GUCY1B1,TJAP1,KCNN1,MYCN,CDK18,PDE1C,PDE4A,PDE4B,PGAM2,MTRF1L,PPARA,MASP1,SLC11A1,ATP10B,DOCK9,CRTC1,THRA,TRPM2,LAT2" Drug 6147_UP Tropine [120-29-6]; Up 200; 28.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ALK,AMPH,BIN1,APBB2,CACNA1G,THSD7A,RUNX1T1,CDH2,ARHGEF10,SIPA1L1,RIMS2,ARMCX2,SGSM2,EDN3,HIPK3,MBNL2,ING4,ERBB2,FER,AGAP2,PDLIM5,RUNDC3A,GSN,MAPT,MMP16,NINJ2,NTRK2,TREM2,CCSER2,RASGRF1,CRTAC1,RFX2,KCNIP1,LIMS2,TMCC1,IZUMO4,KDM4C,ARHGAP26,TBCEL,WSCD1,TCF4,SLC17A7" Drug 2808_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "AP2A2,CDC42BPA,EPB41L5,ARRB2,CFLAR,SPAG9,CLCN3,AKAP7,ENTPD4,CRY2,SOCS5,DZIP3,GPRASP1,GIT2,DTNA,FEM1B,ING4,EZH1,BAIAP2,GHR,TXNL4A,HNMT,IL6ST,KCNH2,MEIS2,NEK1,OGG1,RETREG1,PLXNB1,NDUFS7,ELOVL2,NKAIN1,TMEM231,COA1,EXOC7,TMPO,HIRA,UBE3A,BCL2L13,MFF,PCBP4,PHTF2" Drug 6066_UP Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ADRA1D,BEGAIN,CDC42BPA,ATP2B2,N4BP2L1,CACNA1I,BAIAP3,CAMK2G,SULT4A1,OSBPL3,RASGRP2,PDLIM5,TPK1,FUT9,RUNDC3A,GNAO1,LILRB4,GRB10,SOX21,ICA1,ADAM11,ADAM22,NF1,NTRK2,P2RX7,PFKFB2,TRIM68,RGS4,RPS6KA2,SCN8A,STUM,SLC2A5,SLC11A1,ZSWIM8,SPTAN1,PHLDB1,CRTC1,TPM2,TRIO,TRO,LAT2,ITM2C" Drug 3755_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "MTUS1,ADAM15,TAOK2,LY86,PICK1,ENTPD4,CRMP1,PHF14,CHRDL1,EGFR,ETV1,ANKFY1,PDLIM5,GFER,HTATSF1,MAP4K5,TM6SF1,NEK1,NFIX,CNOT4,PPARA,PRKAB2,PRKAR1B,ZSCAN32,ACSS3,SUPT20H,ASAP3,NLGN1,DZIP1,SNCA,ZHX3,CDK19,ARC,SYN2,SYT1,TBCEL,IQCE,ZEB1,TRIM2,TNS1,RUNDC3B,VLDLR" Drug 4466_DN Rapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "AMPD3,CDK13,ATP6V0A1,ADAM23,BMPR1B,RCBTB2,LHX2,NRXN3,NRG2,ARMCX2,SPOCK3,DMPK,DTNA,ECM2,PLXNC1,ANKMY1,ZNF276,CRCP,ICA1,KIT,NF1,NFIX,PFKFB4,PIK3R1,CCSER2,PLCB2,PRKAR1B,PTX3,ZNF821,KDM4C,SPTB,DDN,LHPP,RPGRIP1L,CHST8,TNS1,RUNDC3B,ZNF711,ZNF24,TRIM9,EPM2A,PHTF2" Drug 2425_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "SEMA6A,SYT13,CDC14B,BMP7,HIP1R,LARGE1,CHRNA4,RAB26,COL9A3,CSF1,PDE4DIP,USP6NL,DMD,MBNL2,CALCRL,ERBB2,BAIAP2,HPCAL4,ZNF44,B4GALNT1,SIGLEC8,SEPT9,POLL,MAPT,MID1,AFDN,MMP16,MYO6,PTPRB,NEK11,S100B,FRMPD1,PKNOX2,DNMBP,RPGRIP1L,PCDHGB6,TK2,AMACR,OSBP2,SEMA3B,KCNAB1,PLSCR4" Drug 2260_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "FZD9,TRMT9B,CDC42BPA,SLC2A11,ADAM15,ADGRB2,CAMK2B,CNR1,CRY2,CNTNAP2,TBC1D5,EIF4G2,RASGRP2,IGSF6,DLC1,ST3GAL6,ZNF589,FGFR1,FGFR3,NSG1,GABRG2,GRM8,MID1,MMP17,PFKFB2,CCDC40,TCP11L1,KCNIP1,FNDC3A,SLC11A1,BTBD7,SMARCA4,SNAP25,FAIM2,IZUMO4,HECW1,TNS1,UCHL1,OSBP2,NT5M,PRDM10,ITM2C" Drug 5119_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ACHE,DNAH17,ATP1A3,ADAM23,ADGRB1,MTMR3,CAMK2B,CRLF1,AKAP7,CRMP1,CSF1R,VCAN,SEC14L5,RIPOR2,EXOG,DTNA,TOM1,PLXNC1,AASS,ING4,SRPK3,FGF1,DCTN2,TRAF3IP2,ERAP1,GFER,LYVE1,GNAL,GPD1,SPACA9,IRAK3,ICA1,PPP2R2B,GRAMD1C,ELOVL2,PTPRH,TMEM231,C1orf54,ZNF821,PKNOX2,KLHL4,PCDHA5" Drug 5241_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,AK2,FAM131A,RGS20,NCOA1,CACNA1I,CFAP410,CRLF1,LHX2,NRG2,CREM,CSNK1E,EGFR,EZH1,FGFR1,SEPT9,SRCAP,GFER,GNG4,GPD2,TDRKH,RASSF8,ATXN2L,AGBL5,IL6R,KCNF1,MID1,MITF,NPR2,MBOAT7,FSD1,MAPK7,SH3BP2,FAM214B,SNCA,DOP1A,DBNDD2,CDK19,TROVE2,AP4E1,TIAM1,SENP7" Drug 7048_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "AGT,AMT,PPP4R4,DNAH17,SLC4A4,SCAPER,CAMK2B,CHN2,DZIP3,DMPK,FAM13A,SUGP2,ETV1,PRELID3A,B4GALNT1,DISC1,USP19,POLL,SHISAL1,KHK,MAN2A2,MBD1,MEF2C,CNOT4,NPTX1,GPR85,POLG,PRKAR1B,RNASE1,RPS6KA2,ASAP3,PEX26,SLC9A5,SLC14A1,KIF13A,KDM4C,PHLDB1,EIF4ENIF1,PLPPR2,WIPF1,EPM2A,SMIM8" Drug 843_UP 5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "AK2,KCNAB2,SLC2A11,CFLAR,SCARB1,PLAA,RCHY1,CREM,CTH,RIMS2,USP6NL,GIT2,CELSR3,ENO2,F8,FGFR1,FHL1,FAM49B,SYT17,DIDO1,INPP5B,KIF2A,LIG4,LYRM9,ZSCAN2,EMID1,FAM214B,SLC11A1,ZKSCAN3,SMARCD3,ZBTB43,DIP2A,STX1A,PLCB1,DNMBP,KIAA1107,SMG6,PCDHA5,GPR161,MAP3K12,NT5M,EVI5" Drug 5430_DN Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,CDC42BPA,ARRB1,BMP7,MAGI1,SOCS6,TAOK2,CLCN3,MFAP3L,EXOG,NR1D2,DTNA,TSPAN5,MBNL2,SEMA4D,GLYR1,RAB30,POLL,CNTRL,GRIK5,MAP4K5,HNMT,IL6ST,JAK2,KITLG,MITF,MPP2,ADAM22,SETD4,PLEC,MAPK12,BTBD7,RBM34,RPGRIP1L,SLC44A1,TK2,HIRA,KCNK12,XRCC4,SPHK2,EPM2A,SENP7" Drug 4298_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ADD2,CDC42BPA,PKP4,EPB41L5,CDK10,N4BP2L1,CAMK2B,RUNX1T1,TPP1,STOML1,RIPOR2,DTNA,MRNIP,REEP2,ZNF44,ERAP1,GDF9,RASSF8,MARK1,MMP16,NF1,NFIX,MTRF1L,STRN3,PPARA,PRKAB2,MAPK10,PTPRD,ZSCAN2,RET,KIRREL1,SH3BP2,DZIP1,SLA,SLC2A5,SPP1,MCF2L,PCDHGA10,HIF3A,TRIO,KAT6A,DPF3" Drug 5979_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "LDLRAD4,CD86,CBFA2T2,ARHGAP33,CBARP,ABCG2,CPS1,PDE4DIP,SPOCK2,DTNB,EDIL3,FCF1,TNK2,DLC1,FGFR1,FLT1,ERAP1,DISC1,POLL,KCNB1,MIA2,MMP16,PDE4A,SERPINI1,RETREG1,ENOX1,BEND5,RGS4,RGS12,CARF,FRMPD1,ARHGAP26,NFASC,MCF2L,ADGRL3,HIF3A,GPR161,TMPO,R3HDM1,ZKSCAN5,ZNF24,SENP7" Drug 2364_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "NDRG3,OSBPL1A,CDK13,CFLAR,BMP7,MTMR3,CA12,CD38,ARHGAP33,CSF1,ARHGEF10,VCAN,ZFYVE16,DAPK3,KIAA0753,PLXNC1,COQ7,ZNF589,FHL1,CELF1,GABRG2,MSL3,GNAO1,GRB10,SLC2A6,KHK,NNAT,NPR2,RGS3,HSPA4L,ZKSCAN3,SNCA,KDM4C,ZC4H2,SEPT8,CEP68,TAL1,PDLIM2,RPGRIP1L,DNAH7,UBE3A,LMF1" Drug 4092_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "C1QTNF3,CDK13,N4BP2L1,ADGRB2,BMP7,SCAPER,MTMR3,CFAP410,CA12,CACNA2D1,DCAF4,MAML1,DRP2,DTNB,RASGRP2,NCALD,DCTN2,NSG1,SIGLEC8,SRCAP,IGF1,ITGA7,KHK,MAN2A2,AFDN,TAGLN3,NEFM,CNOT4,PALM,ENPP2,PLCD1,MTRF1L,PTCH1,RASGRF1,SLA,ZNF334,BTBD7,SNCA,ARHGAP26,SPTAN1,RBM26,TNS1" Drug 7361_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ABHD6,NDRG2,PPP4R4,MARK4,NCOA1,ATP2A2,KIF1A,SYNJ2,SCAPER,RAB29,ARHGEF2,CRLF1,B4GALT6,HOMER3,CNTFR,CSF1R,SIPA1L1,TNK2,ZNF589,PRUNE2,PADI2,ATXN2L,DHX35,MATN3,NPTX1,PAX6,PRODH,SAMD9,C1orf54,SBF1,PPM1E,FAM214B,SOX3,TROVE2,ARHGEF9,PLCB1,AP4E1,CABIN1,PLPPR2,ZNF74,HPS4,ST7" Drug 6224_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASPHD1,ACHE,AP2A2,APOC1,CDC14B,KIF1A,BMP7,CAMK2B,MAGI1,FOXN3,CLCN3,ABI3BP,SH2B1,SIPA1L1,FAM169A,TBC1D5,MBNL2,ING4,ANKMY1,ZNF589,FGF13,FHL1,SYT17,CNTRL,RNFT2,IL6ST,INPP5B,KCNF1,KPNA5,NEK1,RGS12,FAM192A,SYBU,LIMS2,CEP68,STX1A,TRIM2,GPR161,ZBTB14,KCNAB1,MPPE1,TIGD6" Drug 2126_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,KCNAB2,APBB2,STX16,ASIC3,RAB33A,PDE4DIP,CNTNAP2,SNPH,DUSP9,STX2,EZH1,FGF1,FGFR1,DLL3,GRM8,ICA1,JAK2,KCNN1,KIFC3,LMO2,GIT1,SLC11A2,PRKAR1B,PRPH,BCAS3,RGS4,NUDT11,KIRREL1,STUM,BTBD7,SNCA,FNBP1,ERC1,ZBTB43,LHPP,SMG6,SYNE1,TPM1,VGF,WNT7A,ZBTB38" Drug 5112_DN Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "MTUS1,EIF4G3,ALDH7A1,ADGRB2,ARHGEF7,FUBP1,SCARB1,ARMC8,VCAN,CNTNAP2,USP6NL,DYNC1I1,FCF1,CNNM1,VPS26C,ZNF589,SEMA4D,TRMO,COPS8,POLL,MUM1,AGFG1,IFI16,SCIN,INPP5B,JAK2,L1CAM,NF1,CNOT4,PDE4A,STRN3,FSD1,MAPK7,BCAS3,CCDC25,TRAPPC13,MAPK12,ZFP30,HIRA,WIPF1,XRCC4,ZNF225" Drug 1156_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "AP2A2,GAS7,CASK,ARNTL,PDE8B,NCOA1,SYNJ1,ARHGEF7,LDLRAD4,SCARB1,ZMYM4,CHRNA4,AKAP7,ARHGEF10,CTH,KIAA0753,RUSC2,RCAN1,DTNA,F5,SEPT9,VSIG4,ICA1,MAP4,MIA2,MITF,P2RX7,PDE4D,ENPP2,ZFYVE21,TMEM231,FNDC3A,SPP1,THSD1,SS18,RGL1,SLC44A1,PARD3,TFIP11,ZNF225,PRDM10,RNF146" Drug 1650_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "SEMA6A,APBA2,CFLAR,SPAG9,HOMER3,AKAP7,WHRN,CSNK1E,DAPK3,DBT,LYPD1,SPOCK3,TMCC2,FCF1,EPB41L2,ANKMY1,FAM198B,BAIAP2,ZNF276,MSL3,POLL,GRIK5,IRF8,JAK2,KIF2A,MEIS2,CNOT4,PALM,RETREG1,LRP12,ZDHHC14,RNASEL,FBXW7,MAP6D1,CLIP1,ASAP3,FNDC3A,SPART,ARC,SYT1,VGF,EPM2A" Drug 4481_DN Amidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ALK,PPFIA3,SEMA4G,SCAPER,CCNT1,CBFA2T2,ARHGEF2,ARHGAP33,CHN2,LY86,IQCK,CREM,AATK,SPOCK3,TMCC2,DTNA,CNNM1,EIF5,COQ7,SPEG,SCML2,SEC23B,ATP2C1,CGREF1,POLL,MUM1,BACH2,IFI16,SHISAL1,MAPT,BCAS3,PTPRE,TMEM231,MAPK12,KBTBD4,KDM4C,NXT2,SYT1,DICER1,BEX4,TNS1,ZNF711" Drug 4589_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "CDK13,ADAM15,ADGRB2,TPP1,AKAP7,CPS1,AATK,SLITRK5,FAM131B,ARHGAP24,TBC1D5,DBT,ETV1,ZNF589,INPP5K,STON1,GUCY1A1,GUCY1B1,HLF,ITPKA,JAK2,KHK,MT1M,MX1,LYRM9,ZNF862,NDP,NF1,CNOT4,PRKACB,GRAMD1C,ELOVL2,BEND5,ZFP30,ARHGEF40,BTBD7,LIMCH1,ARHGAP26,LHPP,ELOVL4,KIAA1107,ZNF34" Drug 3669_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "MTUS1,NME5,LTBP4,ARHGDIG,ATP6V0A1,ADAM23,CSF1R,CNTNAP2,ARHGAP24,BRINP1,SPOCK3,EXOG,ECM2,ING4,RGS17,PIPOX,F5,HPCAL4,NSG1,GABRG2,SIGLEC8,RUNDC3A,GNAO1,SOX21,NXPH3,HSF2,ICA1,LYRM9,NELL2,PDE4B,SMOX,PID1,RORB,SALL1,LMO3,ATP10B,SYN2,TBL1X,PCDHA5,SLC30A3,KCNAB1,NLRP3" Drug 4781_UP Benperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ACHE,AMH,SPTBN4,ATP2A2,KSR1,SYNJ2,BAIAP3,CFAP410,STOML1,COL9A3,CPS1,CSF1,OSBPL3,SPOCK2,TNK2,C3orf18,MTSS1L,ERCC2,ZNF589,FGFR1,DLL3,FYN,DISC1,GCNT2,GSN,KCNH2,MBD1,NF1,NPTX1,MAPK7,ZSCAN32,EMID1,ASAP3,PEG10,ST5,PLCB1,EXOC7,WSCD1,DOCK9,CABIN1,PHTF2,NLRP3" Drug 5047_DN Chloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASIC1,ADRA1D,TRMT9B,BIN1,APC,LGR5,CDC14B,CDK10,BACH1,HAPLN1,CSF1R,MBNL2,PLEKHA1,ZNF391,CDKL3,BAIAP2,TRAF3IP2,GAD1,SRCAP,ZNF276,KCNMB4,MAPT,MBD1,MX1,PLXNB1,FSD1,RPS6KA2,ATXN7,DZIP1,PPP4R3A,KANSL3,ZNF667,ZNF415,ADGRL3,TCF4,TK2,TRIO,OSBP2,LMF1,UPF3A,MAP3K12,KAT6A" Drug 1701_UP Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.11E-05 1.00E+00 6.05E-04 6.81E-03 42 195 "ASPHD1,AK2,APOC1,ARNTL,CFAP410,SOCS6,RAB28,QKI,CSF1,ARHGEF4,TBC1D5,JAKMIP2,NR1D2,RCAN1,HIPK3,MBNL2,RRAGB,PRKAG2,CGREF1,POLL,HMGCR,ICA1,INPP5B,MAP4,MBD1,MEIS2,NF1,PMP22,CEP41,PRKAR1B,WDR25,RAD51D,PKNOX2,BTBD7,TTBK2,TRIM2,SZT2,ZKSCAN5,REEP1,GDPD5,GAN,SENP7" Drug 6149_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.15E-05 1.00E+00 6.12E-04 6.89E-03 37 164 "MTUS1,BIN1,DNAH17,C5,CD86,CHN2,CREM,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,DOCK4,FAM13A,ING4,ERBB2,BAIAP2,TRAF3IP2,MYT1,TREM2,PCSK5,PDE4B,PDE4D,SERPINI1,PLCL1,PILRA,CARF,SATB1,SGK1,TMCC1,SPTAN1,CDK19,PLCB1,SLC35G2,TK2,FLRT2,LMF1,MAP3K12" Drug CID000005092 rolipram Stitch 3.18E-05 1.00E+00 6.18E-04 6.96E-03 51 253 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,PDE8B,ALDH7A1,CALM1,KRIT1,LRBA,SLIT2,AKAP6,CREM,CRYBB1,CRYM,CSNK1E,CALCRL,DCTN2,AKAP3,DISC1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,GUCY1B1,TNFAIP8L3,SYNPO,IL12A,ITGAM,KCNH2,MAP4,MBP,NPR2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,PKIA,FNDC3A,SSTR1,SSTR2,KAT6B,KAT6A" Drug 6966_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.23E-05 1.00E+00 6.26E-04 7.05E-03 41 189 "ADRA1D,OSBPL1A,BIN1,CDC42BPA,BCAS1,ATP2A2,CRY2,PUM1,ZNF337,BRINP1,MFAP3L,SGSM2,MED12,RASGRP2,FECH,FHL1,HPCAL4,GCK,TDRKH,SPACA9,CACFD1,ICA1,MAP4,MAPT,MGAT3,PDE1C,RETREG1,MBOAT7,KLK6,MORC4,SBF1,HSPA4L,SH3BGR,PEX26,PKNOX2,SLC6A8,CCDC88A,ZKSCAN3,PCDHA6,TK2,FXR1" Drug 4304_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.23E-05 1.00E+00 6.26E-04 7.05E-03 41 189 "ADRA1D,TRMT9B,ARRB1,ATP1A3,SYNJ1,KALRN,NRXN3,WHRN,NCOR2,CYBB,DCAF8,DTNA,DUSP9,LRRC17,SIGLEC8,RUNDC3A,GRIK5,SOX21,ATXN2L,NPTX1,PALM,GPR85,PKM,FXYD1,LRRN3,GDPD2,RFX2,RGS4,SEMA6D,ZFP2,MRAS,ZNF334,SNCA,SP2,ZSWIM8,IQSEC2,DDN,MCF2L,DOCK9,TRO,NDRG4" Drug 3704_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.34E-05 1.00E+00 6.47E-04 7.29E-03 40 183 "NME5,CDK10,ATP6V0A1,CACNA1I,DLGAP2,TPP1,RAB26,HOMER3,NRG2,CSF1R,PDE4DIP,HDAC9,DMD,DTNB,ECM2,ING4,RGS17,ST3GAL6,ZNF589,PRELID3A,NSG1,SYT17,POLL,IFI16,KCNH2,KIFC3,MIA2,PCDH9,PFKFB2,PFKFB4,BEND5,RASA3,SLC11A1,SOX15,SYN2,SYT5,GPR161,TRIO,OSBP2,SPHK2" Drug 4548_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AP2A2,MTUS1,NME5,APBB2,MARK4,CHN2,NRXN3,SLC4A8,AATK,CNTNAP2,FBXL5,EDNRA,PLXNC1,TENM1,MRNIP,COQ7,SPEG,KCNMB4,TDRKH,SYNPO,IL6R,MAP4,TM6SF1,MEIS1,MIA2,SCAMP5,MX1,CNOT4,FAT4,RGS4,ZNF821,AMBRA1,SPTAN1,DDN,TIAM1,CABIN1,TNS1,SMUG1,LMF1,LAT2,NDRG4,EMSY" Drug 6545_UP PHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "C1QTNF1,KCNAB2,GAS7,SEMA4G,ADGRB2,CFLAR,MYRF,CFAP410,CCNT1,CBFA2T2,ARHGEF2,SH2B1,FAM131B,EDIL3,HIPK3,FEM1B,TNK2,EPB41L2,COQ7,ETV1,FGFR1,PRELID3A,GCNT2,GFER,HTATSF1,GUCY1B1,SCIN,JAK2,NFYA,CNOT4,ZNF671,FNDC3A,CDK5RAP2,ZHX3,KDM4C,JMJD6,EXOC7,TBCEL,FBXW11,TFIP11,EMSY,MPPE1" Drug 4683_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AGT,APBB2,GAS7,ADAM23,CACNA1G,LDLRAD4,CAST,SYNGR3,PLEKHB1,NRXN3,RAB26,SH2B1,CNTNAP2,DZIP3,ARHGAP24,DPH1,DTNA,ETV1,ANKMY1,AFF2,FYB1,B4GALNT1,ERAP1,INPP5K,GPER1,CNTRL,RASSF8,NDP,NF1,NFIX,PDE4D,PRKAR1B,PRPH,SUPT20H,PPP4R3A,IZUMO4,ARHGAP26,PHLDB1,ASTN2,TK2,FAM13C,KAT6A" Drug 4403_DN Beclomethasone dipropionate [5534-09-8]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BIN1,APBA2,PLA2G4C,ENTPD4,AKAP12,ABCG1,SPOCK2,SLC12A6,OPTN,APH1A,ERCC2,BAIAP2,FHL1,ERAP1,SRCAP,GNG4,TDRKH,CNTRL,HNMT,KHK,KITLG,GIT1,ADAM22,PLCD1,STRN3,MAPK7,GRAMD1C,EMID1,BTBD7,SNCA,SPART,VPS13A,EXOC7,SMG6,WSCD1,RPGRIP1L,SZT2,ZNF34,HIRA,VIPR2,FIP1L1,KAT6A" Drug 4746_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADD2,AMPD3,AMPH,GAS7,PTCH2,ADAM23,LDLRAD4,CALB2,NRXN3,AKAP7,NRG2,ARHGEF10,INTS1,SPOCK3,AASS,C3orf18,MTSS1L,PRELID3A,FYB1,CHL1,SRCAP,RUNDC3A,IRAK3,ITGA7,MEF2C,MSR1,PCDH8,MAPK7,MAPK10,PTN,C1orf54,PNMA8A,TCP11L1,KCNIP1,SLA,SLC2A5,LIMS2,LIMCH1,TCF4,THRA,SLC17A7,ITM2C" Drug 7240_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "FZD9,AP2A2,SYT13,APAF1,APBA2,PPP4R4,MYRF,RUNX1T1,ARHGEF2,BAG4,ARHGEF10,CNTNAP2,ARHGEF4,MFAP3L,EXOG,F5,AGAP2,GATM,SRCAP,SPACA9,GRM8,KCNF1,AFDN,GIT1,ADAM22,MYO7A,NF1,SLC11A2,ELOVL2,EMID1,RASA3,FRMPD1,ASAP3,SYBU,PHLDB1,DOCK9,SLC19A3,PARD3,PIK3R5,ZKSCAN5,PLSCR4,PHTF2" Drug 4524_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "SYN3,ACHE,ADORA1,C1QTNF3,ANK2,CDK13,ZSCAN18,THSD7A,CAMK2B,CNTFR,SUSD5,VCAN,EDNRB,SRPK3,ZNF391,F5,ABCA8,GCNT2,GNAO1,GNG4,KCNN1,MAPT,MMP16,NF1,PDE4B,PDE4D,PTPRH,ZMAT4,TCP11L1,RASA3,FNDC3A,SLA,ZNF334,SP4,DDN,TROVE2,ARC,SYT5,TACR1,VIPR2,XRCC4,KCNAB1" Drug 4723_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADORA2A,DOC2A,APBB2,ADAM23,CAMK2B,RAB28,CSF1R,HDAC4,DAPK3,BRINP1,RUSC2,SPOCK3,CDON,DTNA,OPTN,FYB1,TMEM8B,SRCAP,GFER,MSL3,PCLO,HNMT,KCNF1,KCNN1,MAPT,ADAM22,NF1,LRP12,MAPK7,ELOVL2,PTN,FAM184A,FBXW7,SH3BP2,ASTN2,EXOC7,TMEM121,AP4E1,TK2,PARD3,VIPR2,DNALI1" Drug 6501_UP Aminocaproic acid [60-32-2]; Up 200; 30.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "SPARCL1,LTBP4,MARK4,NRP2,BAIAP3,CFAP410,CBARP,FOXN3,TAOK2,CNN3,AKAP6,COL9A3,SNCAIP,BRINP1,RUSC2,RCAN1,MBNL2,ERCC2,ST3GAL6,ZNF589,NSG1,OGA,ALDH1L1,POLL,GPER1,KIF5A,MYO7A,TREM2,PLTP,MAPK7,PTX3,RGS12,SCN2B,ARHGEF40,ARC,WSCD1,SLC44A1,THRA,CABIN1,WNT7A,XRCC4,SLC30A3" Drug 3572_UP Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NDRG2,ADRA1D,SYT13,CDC42BPA,APLP1,BCAS1,CA4,DLGAP2,ARHGEF6,CRYM,FAM169A,EIF4G2,TENM1,STX2,OLFM1,GAD1,TMEM8B,SIGLEC8,NEU3,LYVE1,RUNDC3A,ITGAM,ADAM11,CNOT4,PFKFB2,PLCD1,ZSCAN32,FAM214B,KANSL3,PKNOX2,KDM4B,NMNAT2,THSD1,CRTC1,ICAM5,PARD3,TNS1,PIK3R5,VGF,KCNAB1,SENP7,JPH3" Drug 2441_DN Amphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BIN1,MARK4,SCARB1,STOML1,ABCG1,VCAN,PPP6R2,DGKG,SPATA2,CNNM1,PLEKHA1,FHL1,AGAP2,SEMA4D,ERAP1,INPP5K,LILRA2,NCKAP1L,LSS,GIT1,CNOT4,NPR2,PLCB2,SLC25A23,PRKAR1B,MAPK10,CNNM2,CNTLN,FAM184A,ZCWPW1,MRAS,SH3BP2,FAM102A,FAM214B,SLC11A1,KDM4B,DBNDD2,TROVE2,ARHGEF9,OBSL1,KAT6B,UBE3B" Drug 2952_DN Betulin [473-98-3]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BRAP,AMT,APAF1,CDK10,SLC4A4,C5,CAPN3,CBFA2T2,SOCS6,IQCK,CREM,SIPA1L1,PDE4DIP,CST3,DOCK4,RUSC2,TSPAN5,FAM13A,EIF1,ENO2,NCALD,PIPOX,LILRA2,GSN,SCAMP5,MX1,NPR2,SLC11A2,PFKFB4,PIK3R1,RGS3,MAP6D1,ZNF821,DZIP1,ANKRD6,DDN,DNMBP,TCF4,EVI5,GDPD5,PRDM10,PLSCR4" Drug 3706_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1D,AGT,NME5,LTBP4,BEGAIN,PPP4R4,ZSCAN18,RASL11B,NRP2,BMP7,SYNJ1,C5,CFAP410,USP2,CNTFR,CREM,CYBB,SPOCK2,HS3ST2,ECM2,EDIL3,EDN1,EGFR,EPHB1,DLC1,FGFR1,GDF9,LPAR4,GRM2,SOX21,KCNH2,LSS,MEF2C,CLDN11,CDK18,ELOVL2,PTPRD,RFX2,ZNF334,CRTC1,TRO,SPHK2" Drug 5888_UP Mesalamine [89-57-6]; Up 200; 26.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AP2A2,PPP4R4,ARRB2,CFAP410,CACNA1A,ARHGAP33,QKI,AKAP7,ARHGEF10,BRINP1,MBNL2,TNK2,HSD17B14,TUBD1,FGF1,ADAM28,GNAO1,PRRC2B,GPR37,GRM8,GSTM5,MAPT,MYO7A,NRCAM,PDE4B,RETREG1,NECAB2,RAD51D,FBXW7,NLGN1,DZIP1,MYH15,IFT122,LIMCH1,TSNAXIP1,HECW1,ARHGAP26,CAMTA2,SLC44A1,RIMBP2,XRCC4,NT5M" Drug 3032_DN Fluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "APOC1,AZGP1,BACH1,SCAPER,LDLRAD4,CAPN3,HIP1R,SLC16A4,B4GALT6,STOML1,QKI,DBN1,RUSC2,EXOG,DTNA,F5,ST3GAL6,FER,FHL1,PDLIM5,LILRA2,ATXN2L,ICA1,TJAP1,KHK,MGAT3,AFF1,N6AMT1,NF1,NINJ2,PDE4B,MAPK9,PTCH1,NEK11,FAM214B,SS18,ADGRL3,TCF4,TPM1,LAT2,ZNF225,NLRP3" Drug 6060_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADORA1,AMPD3,BIN1,CDK13,SLC4A4,CALB1,CAMK2B,EDNRA,MTSS1L,ZNF589,BAIAP2,NSG1,DLL3,FYB1,GPER1,CACFD1,GRM8,SYNPO,IFI16,KCNN1,MEF2C,ADAM22,PDE4D,LRRN3,PRKCB,PTX3,KHDRBS2,ZMAT4,RFX2,RGS12,CCDC88A,CXXC4,KDM4B,DOK5,ZSWIM8,PEG10,TRIM2,CRTC1,TNS1,VIPR2,SPHK2,SLC17A7" Drug 4772_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NDRG2,APC,CACNA1G,BAIAP3,LDLRAD4,CFAP410,LDB2,ARHGEF2,PLEKHB1,CNTFR,CPS1,OSBPL3,VCAN,PPP6R2,GIT2,DMPK,AASS,C3orf18,HSD17B14,F5,ZNF589,AFF2,FYN,GFER,GRB10,HLF,IRF8,KCNJ5,KCNQ3,NEFM,CLDN11,PDE4A,RGS12,TCP11L1,SH3BP2,KDM4C,UNC5B,ARHGAP26,PLCB1,SLC30A3,KCNAB1,JPH3" Drug 4548_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "PPP4R4,ADGRB1,CFLAR,LDLRAD4,HAP1,CAMK2B,RHBDL1,LARGE1,CSF1R,PDE4DIP,ERC2,DAPK3,SPOCK3,CDON,DTNA,NRN1,F5,FGF1,ERAP1,GNG4,TPPP,IRF8,KIT,NF1,NPTX1,NRCAM,PDE4D,PFKFB2,RETREG1,LRRN3,TCP11L1,SUPT20H,KANSL3,DOK5,ZNF423,SPTB,PHLDB1,SYN2,MCF2L,PIK3R5,CHST5,SSBP2" Drug 7531_DN 0393-0188; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "FAM135A,AMPD3,APOC1,SYNJ2,HAP1,CLGN,SOCS6,JAKMIP2,DLC1,FLNC,GALC,TMEM8B,SEPT9,LYVE1,NXPH3,ELOVL5,ITPKB,JAK2,TM6SF1,NELL2,SLC11A2,PALM,PCDHGC3,PCDH9,MINDY2,PPP5C,GDPD2,SNRK,TMEM104,RFX3,KCTD17,TCP11L1,SGK1,FAM214B,SNCA,TROVE2,RGL1,SZT2,BEX4,TRO,SPHK2,RNF170" Drug 4154_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AK2,LTBP4,BEGAIN,ANK2,APLP1,CFLAR,MTMR3,SLC16A4,CNTNAP2,GSDME,HS3ST2,DTNB,EDNRA,AGAP2,NSG1,OGA,GNAL,ATXN2L,KCNB1,KCNJ5,MID1,ZNF862,TREM2,MAPK7,PTCH1,ELOVL2,ACSM5,BEND5,NUDT11,ST6GAL1,PKNOX2,SLC14A1,SNCA,ZBTB43,ATP10B,JMJD6,PCDHGA10,CRTC1,ZNF34,TRIO,LAT2,NT5M" Drug 7184_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AK2,APOC1,ADAM15,BCL7A,CFLAR,SYNJ2,GYG2,BAIAP3,CA4,SCARB1,AP4M1,CACNA2D2,RAB28,LRIG1,PDE4DIP,RASSF2,DAPK3,GIT2,LYPD1,RCAN1,HSD17B14,DLC1,FHL1,SEMA4D,ZNF44,SIGLEC8,DISC1,SLC2A6,ACOT7,NFYA,NPR2,NPTX1,PTN,BTBD7,CDK5RAP2,SNCA,SPTAN1,CLASP2,SS18,STX1A,VIPR2,SEMA3B" Drug 6777_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AP2A2,CDC42BPA,ARRB1,PLA2G4C,CAMK2G,B4GALT6,SLIT2,TPP1,CRY2,ARHGEF10,CTH,DNM1,FGFR3,FAM49B,CSPG5,ERAP1,DISC1,SRCAP,CNTRL,BTN2A1,INPP5B,MATK,NEK1,NFYA,CNOT4,SMIM7,STRN3,FSD1,RAD51D,FAM184A,GSTCD,ABLIM3,SOX3,SPATA7,TSPYL2,NXT2,KLHL7,ARC,PARD3,CDK20,UPF3A,SMIM8" Drug 4749_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ABHD6,ADRA1D,NME5,LTBP4,FAM131A,CDC14B,ZBTB10,EIF4G3,BCL7A,CFAP410,CAMK2G,TAOK2,FAM189A2,CREM,ARHGEF4,PPP6R2,SLC12A6,DLC1,AFF2,ATXN2L,IL6ST,MEF2C,KITLG,NF1,NFYA,CNOT4,RETREG1,LRP12,SAMD9,RGS3,FERMT1,LIMCH1,ZNF423,SPTAN1,CDK19,TTBK2,STX1A,ARC,TNS2,SLC44A1,ZNF74,EVI5" Drug 2727_DN Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NDRG2,AMPD3,BIN1,CDC42BPA,APAF1,APOC1,PPP4R4,FUBP1,HIP1R,EPS15L1,IQCK,NRG2,CREM,SIPA1L1,MFAP3L,CELSR3,RRAGB,F5,ZNF589,PDLIM5,KHDRBS3,SRCAP,ZNF276,GPR75,GNG4,LILRA2,TJAP1,MAP4,AFF1,NF1,PCDH9,SMIM7,POU6F1,ZNF821,SH3BP2,ARHGAP26,DDN,TROVE2,KIAA1107,CRTC1,CLIP2,MAP3K12" Drug 2424_DN Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADORA2A,PPFIA4,APBB2,FOXN3,STOML1,BAG4,CREM,CRY2,DGKG,C2CD2L,ING4,SRCAP,COPS8,LILRA2,PADI2,AGFG1,JAK2,LSS,SMAD1,MAP4,NF1,NINJ2,NPR2,SLC11A2,PDE4D,GPR85,PPP3CC,CNNM2,ZNF493,SH3BP2,PEX26,SPTAN1,CDK19,ZBTB43,CEP68,ARHGEF9,ADGRL3,FBXW11,TBL1X,KAT6B,ZKSCAN5,GDPD5" Drug 5249_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ASPHD1,ALCAM,CFLAR,CAMK2G,KRIT1,PLEKHB1,STOML1,QKI,HOMER3,TBC1D5,DBT,DTNA,HIPK3,ENO2,ACSL4,FGFR1,ANKFY1,FAM49B,GALC,MSL3,RNFT2,HMGCR,ITPKB,JAK2,ADAM22,CNOT4,SLC11A2,RETREG1,LRP12,PRKAR1B,ROBO1,FBXW7,PPP4R3A,UHRF1BP1L,SPART,THSD1,PRRC2C,ASTN2,AP4E1,ZNF34,TMPO,ZNF189" Drug 6557_UP AG-028671 [847803-03-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "CDK13,CCNT1,CDC42BPB,HINFP,FAM131B,ARHGAP24,GIT2,MRNIP,CDKL3,ETV1,FGFR3,FYB1,INPP5K,GLYR1,SOX21,PADI2,BACH2,IL12A,JAK2,KCNJ5,MAPT,MIA2,SLC11A2,PRKAR1B,PTPRH,PPP4R3A,LIMS2,KDM4C,ARHGAP26,ZBTB43,CEP68,ASTN2,EXOC7,KIAA1107,TCF4,TNS2,SLC35G2,TK2,TPM2,SPHK2,MPPE1,PLSCR4" Drug 2740_UP Pyrithyldione [77-04-3]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "TRMT9B,DNAH17,AZGP1,RGS9,KSR1,CHRNA4,PLAA,HAPLN1,NCOR2,RGS6,PDE4DIP,BRINP1,MFAP3L,CDON,MBNL2,AASS,DLC1,FHL1,ZNF44,SEPT9,GPD1,GRM8,MAPT,MGAT3,AFDN,MYO6,PPP1R1A,PTPRB,SCN2B,MRAS,CCDC92,NLGN1,KANSL3,ZNF415,SYT5,TAL1,TRIO,TRO,LMF1,XRCC4,SLC17A7,FAM13C" Drug 3116_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BIN1,SEMA4G,RASL11B,AZGP1,NRP2,KSR1,BMP7,FUBP1,CALB2,THSD7A,CAPN3,STOML1,SLC4A8,ABI3BP,CPS1,PDE4DIP,SPOCK3,CDON,CELSR3,F5,FOXF2,GRM8,SCIN,KIFC3,MAPT,TAGLN3,NFIX,SLC11A2,NTRK2,PEX26,ZSWIM8,TSPYL2,SPART,SMG6,TRIM2,SZT2,THRA,FAM155A,PLPPR2,XRCC4,SPHK2,ADAMTSL3" Drug 4111_UP Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AMPD3,GAS7,ARRB1,RCBTB2,SULT4A1,WHRN,CRY2,AATK,ARMCX2,SNX29,EPHB1,SCML2,KHDRBS3,SRCAP,CSDC2,ICA1,MSI1,ADAM22,PLCD1,C19orf57,CEP41,PRKCB,MAPK7,ZSCAN2,TRIM68,PNMA8A,EMID1,STUM,SH3BP2,PKNOX2,LIMCH1,DOP1A,HECW1,CDK19,KIAA1107,PCDHGA10,CDK20,UBE2H,UGT8,SLC17A7,KCNAB1,PARP11" Drug 5937_DN LY294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NDRG2,NME5,SEMA6A,BEGAIN,APC,SYNJ1,GYG2,CA12,CACNA2D1,TAOK2,COL9A3,C2CD2,CRMP1,FAM169A,ARHGEF4,DTNA,ACSL4,B4GALNT1,MALT1,GRIK5,MAP4K5,ITPKB,JAK2,KCNF1,KCNN1,NPTX1,GRAMD1C,RIPOR1,RET,RGS3,SGK1,JMJD6,ARC,ASTN2,KIAA0930,TRIM2,RPGRIP1L,DOCK9,VLDLR,XRCC4,SPHK2,RNF146" Drug 4236_DN Gabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1D,TRMT9B,APC,PPFIA3,CDK10,TAOK2,PLAA,RAB26,CSNK1E,PPP6R2,ARMCX2,DTNA,MBNL2,MTSS1L,EZH1,SEMA4D,ZNF44,RUNDC3A,MAPT,MEF2C,ADAM22,NPR2,PLXNB1,PRKAR1B,ELOVL2,ZSCAN32,PTPRB,RGS4,KIRREL1,SBF1,ATXN7,FRMPD1,FAM214B,KANSL3,ELMO2,TSNAXIP1,DOK5,TPM2,OSBP2,VGF,KCNAB1,TIGD6" Drug 6873_DN "H-89, Dihydrochloride; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BIN1,APBB2,CDK10,CDK13,CFLAR,SYNJ2,CDH2,HOMER3,SLC4A8,CPS1,DZIP3,ZFYVE16,SGSM2,ABCC5,TENM1,ETV1,FGF13,FGFR1,FHL1,GLI2,POLL,NXPH3,KIFC3,SLC11A2,OCRL,PLEC,SAFB,SIRT2,SLC9A5,SLC14A1,BTBD7,ZNF667,SMARCD3,POGZ,SYT1,KIAA0930,BHLHB9,FAM155A,LMF1,WIPF1,XRCC4,PHTF2" Drug 7337_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "TRMT9B,APBB2,APLP1,FAM131A,PPP4R4,ARHGDIG,MARK4,ADGRB2,LDLRAD4,ABCG1,FAM169A,SNPH,PARD6A,PHF20L1,MRNIP,ERCC2,ZNF44,MALT1,TDRKH,IL6ST,CNOT4,NPTX1,NTRK3,PCDHGC3,DUSP26,LRP12,MAPK7,ZSCAN32,KHDRBS2,RGS12,ZNF821,PREX2,BTBD7,SMARCC2,SNAP25,SNCA,RBM26,PLCB1,RUNDC3B,FAM155A,FLRT2,VLDLR" Drug 6063_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "BIN1,GAS7,ALDH7A1,RGS9,NRP2,CACNA1I,MTMR7,CD38,CDH2,HAPLN1,AATK,SPOCK3,DUSP9,SRPK3,AFF2,FYB1,ALDH1L1,ADAM28,PCLO,GRM8,HNMT,ICA1,IGF1,KIT,AFDN,NOVA1,RELN,PTPRO,RASGRF1,KHDRBS2,SCN8A,SLC4A3,SLC11A1,SNAP25,ZSWIM8,IZUMO4,HECW1,TAL1,PCDHGB6,OBSL1,LAT2,ZNF711" Drug 5446_DN Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ASPHD1,ASIC1,AP2A2,PDE8B,SLC4A4,CFLAR,SCAPER,GYG2,CFAP410,CLGN,TAOK2,HOMER3,GIT2,RCAN1,ANKMY1,FGFR1,IQCG,SEMA4D,CGREF1,GRB10,GRIK5,HNMT,IL6ST,KPNA5,LMO2,KITLG,MMP16,ADAM22,ZNF862,RGS12,SLC6A8,KDM4B,TTBK2,VPS13A,MCF2L,EXOC7,RPGRIP1L,SLC44A1,TK2,PARD3,ZFP37,EPM2A" Drug 4250_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ASPHD1,ADORA1,NME5,PKP4,BACH1,NRP2,SYNJ2,CALB2,HAP1,CNTN1,CNTNAP2,RIMS2,HS3ST2,DTNA,PTK2B,SYT17,SRCAP,GNAO1,ICA1,KCNB1,KIT,MAP2,NF1,PTPRN2,ACSS3,KLHL11,PBRM1,CARF,PNMA8A,GSTCD,RPS20,SPTB,CDK19,ARHGEF9,ASTN2,MCF2L,TBCEL,GPR161,ZNF34,FLRT2,ZNF24,ZNF225" Drug 4415_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ASIC1,NDRG2,ADCY6,APAF1,CDC14B,ARHGDIG,RASL11B,HAP1,CD86,CACNA2D2,RGS6,FAM13A,MBNL2,ELN,LRRC17,FGFR1,FHL1,PDLIM5,NSG1,FYB1,SYNPO,IL12A,KCNJ5,ADAM22,GPR85,PFKFB2,PLCB2,MTRF1L,PLXNB1,PTPRB,CCDC40,RORB,RTN1,SEMA6D,SH3BP2,SH3GL3,SLC11A1,ATP10B,SYNE1,DOCK9,TNS1,ZNF154" Drug 6015_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AP2A2,ALCAM,AMH,AMT,APBA2,APLP1,NCOA1,SLC2A11,ADAM23,BCL7A,MTMR3,CBFA2T2,ARHGEF2,ARHGAP33,VAX2,AKAP7,CREM,LRIG1,PDE4DIP,CNTNAP2,CDON,FCF1,MRNIP,GLYR1,RAB30,MAP4,MBD1,LYRM9,NF1,SAMD9,NKAIN1,ROBO1,ANKRD6,EPN2,FAM214B,CXXC4,SNCA,CEP68,IQCE,CABIN1,LMF1,ZFP37" Drug 3668_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADGRF5,TRMT9B,GAS7,ATP6V0A1,ADAM23,BMP7,CACNA2D1,DCLK1,ABCG2,HAPLN1,MYEF2,ECM2,IGSF6,FGFR1,HPCAL4,TMEM8B,HPGDS,GLI2,GRM8,IL12A,ITGA7,KCNJ5,ADAM22,NRCAM,LRRN3,ZSCAN2,NKAIN1,CCDC40,STUM,SH3BP2,CNKSR2,ZHX3,UNC5B,ZC3H13,NFASC,PLCB1,SYT5,TAL1,TNS1,UCHL1,VIPR2,EPM2A" Drug 6200_DN "estradiol, USP; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ABHD6,ADD2,MTUS1,SCAPER,CAPN3,TAOK2,PLAA,CNTN1,AKAP7,CREM,ENTPD4,SH2B1,CRY2,SEC14L5,GSDME,SGSM2,CELSR3,FAM13A,GAA,SRCAP,GNG4,CACFD1,SOX21,TJAP1,IL6ST,SMAD1,NF1,OGG1,STRN3,BCAS3,GALNT10,LIMS2,SLC6A8,DDN,KIAA1107,CUX2,ZKSCAN5,LAT2,MAP3K12,EVI5,GDPD5,NLRP3" Drug 4169_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "SYN3,ADORA1,CDC14B,ARSE,LDLRAD4,CALB1,KALRN,CAMK2B,CHN2,STOML1,ARHGEF10,DAPK1,DRP2,DTNA,DTNB,SNX29,EDN1,C3orf18,SPEG,FHL1,OGA,SIGLEC8,GFER,RUNDC3A,PRDM5,GRM8,IL6R,MEF2C,AFF1,MX1,TREM2,ELOVL2,NKAIN1,SLC11A1,TSNAXIP1,PEG10,PHLDB1,TNS1,CHST5,VGF,WIPF1,AP3B2" Drug 6504_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "LTBP4,ATP6V0A1,RGS11,LDLRAD4,CACNA2D1,CAMK2A,CAMK2B,CTH,GREB1,SPOCK2,GIT2,RCAN1,DTNA,EDNRA,AASS,TNK2,FOXF2,ANKFY1,AFF2,NSG1,OGA,GALC,HPGDS,IL6ST,KCNN1,ELOVL2,PTPRB,TRIM68,DCUN1D2,GSTCD,SBF1,CNKSR2,PREX2,EXOC7,TRIM2,SYNE1,ZNF34,BEX4,CDK20,LAT2,SLC30A3,GDPD5" Drug 2776_DN Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ABHD6,AMPD2,APBB2,PPFIA3,BCL7A,CBFA2T2,PLEKHB1,FAM189A2,SIPA1L1,PPP6R2,MFAP3L,CNNM1,CDKL3,F8,ZNF589,DISC1,GNG4,HNMT,DHX35,KCNN1,MEIS2,LYRM9,ZNF862,CNOT4,NPR2,PDE4A,PLEC,PTPRE,ZSCAN2,TCP11L1,PEX26,SLC6A8,ZKSCAN3,TSPYL2,STX1A,VPS13A,EXOC7,KIAA1107,RPGRIP1L,PLPPR2,MAP3K12,MPPE1" Drug 4596_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "RALGAPA1,LTBP4,KSR1,BMP7,BAIAP3,CACNA2D2,STOML1,CDC42BPB,CREM,CRY2,ABCG1,CNTNAP2,ARHGEF4,SNPH,SPOCK2,C2CD2L,SPOCK3,FGFR1,SEMA4D,ZNF44,RUNDC3A,CACFD1,ATXN2L,GIT1,NELL2,NOVA2,POLG,SNRK,PTN,PTPRO,CCDC40,KCTD17,FBXW7,MAPK12,SLC2A5,ARHGEF9,EXOC7,PCDHA5,GPR161,WNT7A,KCNK12,KCNAB1" Drug 3302_DN Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AP2A2,AK2,ALCAM,APBA2,KCNAB2,EPB41L5,GAS7,APOC1,STX16,CFLAR,SYNJ2,ARHGEF1,QKI,ENTPD4,FAM169A,GREB1,DAPK3,ARMCX2,MBNL2,INPP5K,PRRC2B,HNMT,TJAP1,ITPKB,IPO5,MAP4,MPP2,MSI1,NEK1,GTDC1,SLC25A36,NEK11,RPS6KA2,FAM214B,LIMCH1,RBM34,EXOC7,TBL1X,PCDHA6,PLPPR2,ZFP37,ST7" Drug 6571_DN Prostaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "C1QTNF3,APBB2,APOC1,PPFIA3,CFAP410,CCNT1,CHN2,NRG2,SPOCK2,RHOBTB1,DTNA,ING4,KAT8,FGFR1,BAIAP2,FLT1,GCNT2,AHDC1,COPS8,KHK,MIA2,MN1,LYRM9,SLC11A2,SAMD9,PTPRH,PTX3,SH3TC2,RNASEL,RPS6KA2,MAPK12,SH3BP2,ASAP3,CNKSR2,LIMS2,KDM4D,DOP1A,PBLD,TNS1,RPRM,NAV3,KCNAB1" Drug 4600_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1D,LTBP4,GAS7,BCAS1,CFLAR,CACNA1I,CFAP410,ARHGEF2,LARGE1,RAB28,CREM,ABCG1,PDE4DIP,CNTNAP2,C2CD2L,DMPK,TENM1,ING4,DLC1,GPD2,CNTRL,AFF1,NF1,PALM,PCDH9,ENOX1,FBXW7,ST6GAL1,SNCA,KDM4B,TSNAXIP1,UNC5B,ARHGAP26,RBM26,HIF3A,RIMBP2,TNS1,CDK20,ZNF711,REEP1,SLC17A7,KCNAB1" Drug 3696_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADD2,MTUS1,NME5,SEMA7A,CDC14B,CDK10,PTCH2,N4BP2L1,MTMR3,GYG2,MAGI1,CBARP,VAX2,AKAP7,AATK,MYEF2,MFAP3L,ZNF391,OLFM1,PDLIM5,CGREF1,GRM2,NXPH3,IL12A,KPNA5,NELL2,LRRN3,PTPRN2,PTPRO,ZSCAN2,NKAIN1,RAD51D,RFX2,SLC11A1,IZUMO4,UNC5B,SYN2,KLHL4,ZEB1,CRTC1,SPHK2,NLRP3" Drug 3703_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "C1QTNF3,APBB2,GAS7,CDK10,CDK13,MTMR2,MYRF,BAIAP3,KYAT1,NRXN3,IQCK,SLITRK5,SPOCK2,PLXNC1,TNK2,STX2,FGFR1,PRELID3A,OGA,FYN,TRAF3IP2,ERAP1,GCNT2,SRCAP,PCDH17,BACH2,ICA1,TJAP1,ADAM22,NDP,NPR2,RETREG1,CEP41,ZCWPW1,DZIP1,PEX26,ARHGEF40,ARHGAP26,MCF2L,TCF4,THRA,LAT2" Drug 5510_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AGT,AK2,SYT13,AMPD3,APAF1,DNAH17,CFAP410,CACNA1A,HIP1R,CBFA2T2,PLEKHB1,CSF1,IPCEF1,RIMS2,DTNA,MBNL2,LRRC17,KAT8,GPER1,ADAMTS13,ATXN2L,HNMT,KHK,NF1,PTPRD,ACSM5,MARCH1,CCDC102B,SCN8A,SH3GL3,FRMPD1,ST6GAL1,PKNOX2,BTBD7,SNAP25,PEG10,ARHGAP26,IQSEC2,STX1A,PLCB1,KIAA0930,XRCC4" Drug 6053_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AMH,GAS7,PLA2G4C,DNAH17,GYG2,CLGN,CHN2,EPS15L1,WHRN,ARHGEF10,CYBB,SPOCK2,MFAP3L,GSDME,DYNC1I1,EDNRA,HSD17B14,RUNDC3A,HPGDS,GRM2,SOX21,ATXN2L,ITGAM,KCNN1,CLDN11,LRP12,MAPK7,SCN8A,MRAS,PEX26,SLC9A5,SLC11A1,SMARCD3,SNAP25,ATP10B,NXT2,ARC,TBCEL,DOCK9,LAT2,SLC30A3,EMSY" Drug 3452_DN Methacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "OGT,CDC42BPA,FAM131A,CFAP410,PLAA,CLCN3,QKI,HINFP,SIPA1L1,GPRASP1,HDAC4,MFAP3L,PARD6A,SGSM2,DTNA,BAIAP2,GCNT2,GLYR1,RAB30,CNTRL,GRB10,ATXN2L,INPP5B,IPO5,MBD1,MPP2,ADAM22,NFYA,RETREG1,CNNM2,ELOVL2,ZSCAN32,TMCC1,KDM4B,TSPYL2,SPART,PLCB1,TACC1,ANKRD12,ZNF32,EPM2A,SMIM8" Drug 1696_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "LTBP4,CDC42BPA,SHROOM2,CDK13,RIPK1,SYNJ2,CAMK2G,AKAP7,PPP6R2,HDAC4,GIT2,SUGP2,VPS26C,FGFR3,FAM49B,CSPG5,GAA,TRAF3IP2,SRCAP,ITPKB,MAP4,NPR2,SLC11A2,SLC25A23,NEK11,GALNT10,ZSWIM8,ERC1,ELOVL4,COBL,TACC1,MCF2L,EXOC7,IQCE,TBL1X,KIAA0930,HIRA,PLPPR2,LMF1,KLC2,MAP3K12,SMIM8" Drug 2958_UP Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1B,MTUS1,CDC42BPA,KCNAB2,SYNJ2,CFAP410,HOMER3,CREM,OSBPL3,PDE4DIP,ZNF337,SV2B,RASGRP2,FGFR3,FHL1,AGAP2,PDLIM5,CAMKK2,GATM,ALDH1L1,PADI2,NEK1,NOVA2,SLC11A2,POU6F1,BEND5,PNMA8A,SEMA6D,ZNF821,RASA3,FAM102A,TMCC1,SPTAN1,EXOC7,PDLIM2,SZT2,PCDHGA10,SYNE1,TNS1,CHST5,UBTF,ZNF142" Drug 2871_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "RALGAPA1,FZD9,GAS7,MARK4,ADAM23,AZGP1,CACNA1A,ARHGAP33,ARHGEF6,WHRN,AKAP5,PLXNC1,C3orf18,ERCC2,SPEG,OLFM1,BAIAP2,AGAP2,SEMA4D,PDLIM5,FAM49B,SRCAP,GFER,NF1,NNAT,PBRM1,EMID1,STUM,SH3BP2,FAM214B,LIMCH1,SPTB,SYN2,DOCK9,TMEM121,GPR161,CHST5,PDIA2,FLRT2,SLC30A3,EVI5,DPF3" Drug 6035_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ASIC1,KCNAB2,APC,CDC14B,ST3GAL5,CACNA1I,CFAP410,CBFA2T2,ARHGEF2,SEPT7,TAOK2,AKAP7,CSF1,GREB1,JAKMIP2,MFAP3L,TMCC2,CDON,HIPK3,CNNM1,COQ7,FHL1,PDLIM5,TXNL4A,GLYR1,RAB30,POLL,SMAD1,MAP4,GIT1,ADAM22,SMIM7,PRODH,PRPH,TMEM104,CEP97,ZFHX4,ZNF821,CEP68,EXOC7,PCDHA5,TK2" Drug 5642_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NDRG2,NME5,KCNAB2,PPP4R4,SCAPER,CACNA1I,CLGN,RCBTB2,FOXN3,STOML1,SULT4A1,RCHY1,PDE4DIP,CTH,IGSF6,SCML2,FHL1,AFF2,GLYR1,GNG4,GPER1,CNTRL,CACFD1,HLF,KCNN2,AFF1,MMP16,NTRK2,LRP12,PPARA,ELOVL2,ZSCAN32,FERMT1,COA1,SMARCD3,TROVE2,TBCEL,CRTC1,PCDHA5,FAM155A,KCNK12,EPM2A" Drug 874_UP (-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1D,ANK2,APBB2,CDC14B,RGS9,GYG2,CAMK2A,COL9A3,RIMS2,MFAP3L,TOM1,TSPAN5,EGFR,AASS,FYB1,DISC1,SEPT9,NEU3,LIG4,NPTX1,PCDH9,MAPK7,PTPRB,RIPOR1,RASGRF1,KHDRBS2,CARF,EMID1,ATXN7,ASAP3,NLGN1,PPP4R3A,KANSL3,SPTAN1,DIP2A,ANKRD12,SYNE1,VGF,VIPR2,WIPF1,MAP3K12,NT5M" Drug 5058_UP "Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ALK,SEMA7A,APAF1,ADAM23,RGS9,NRP2,CFLAR,LDLRAD4,RUNX1T1,CNTFR,WHRN,PYGO1,MFAP3L,DPP6,COQ7,F5,AGAP2,GNAO1,ADAMTS13,GRIK5,KIT,MSI1,NNAT,NOVA2,OGG1,PALM,RETREG1,LRRN3,SAMD9,RGS12,KCTD17,ST6GAL1,CNKSR2,SNAP25,SNCA,SPP1,UNC5B,SYP,ZFPM2,TRIO,TUBB1,VGF" Drug 4416_DN Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "AK2,DOC2A,AMH,AMPD3,GAS7,APOC1,BCL7A,CFLAR,CAMK2B,MAGI1,CACNA2D2,STOML1,CPS1,C2CD2L,ACSL4,DLC1,FGF13,BAIAP2,FHL1,PDLIM5,SRCAP,TXNL4A,GNG4,ATXN2L,ICA1,KHK,KIT,MAP4,MMP16,NPR2,PRKAR1B,MAPK7,CCDC25,EMID1,BTBD7,SNCA,TBL1X,WSCD1,HIRA,FLRT2,KCNK12,SLC17A7" Drug 7479_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADD2,NME5,BIN1,APBA2,MARK4,SYNJ1,SCAPER,USP2,FOXN3,TPP1,PICK1,AKAP12,SEC14L5,MYEF2,EDN1,ENO2,OGA,SYT17,DISC1,SRCAP,RAB30,GPER1,ITPKB,KCNQ3,MAP4,MPP2,NCAM2,CNOT4,PDE4A,NLE1,PLXNB1,WDR25,ZSCAN32,SH3BP2,FAM214B,SLC11A1,ZHX3,WSCD1,CRTC1,DICER1,TRIO,XRCC4" Drug 4784_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADRA1D,APBA2,APC,MARK4,ATP1A3,AZGP1,LDLRAD4,CACNA1A,FOXN3,PLEKHB1,TPP1,QKI,ARHGEF6,WHRN,CRMP1,VCAN,ARHGAP24,MFAP3L,PLXNC1,EIF4G2,RRAGB,DLC1,CAMKK2,DISC1,GPD2,PCLO,KCNN2,TAGLN3,NF1,NOVA2,LRRN3,PRKAR1B,ENOX1,ZFHX4,EMID1,FRMPD1,SYBU,SLC14A1,ZNF415,NEK4,FBXW11,ZNF45" Drug 4497_DN Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "NME5,APOC1,SYNJ1,SYNJ2,SCAPER,MYRF,IL33,SCARB1,RAB28,LY86,AKAP7,WHRN,VCAN,GIT2,SPATA2,MFAP3L,DTNA,EGFR,TNK2,EPB41L2,SPEG,FGFR1,CGREF1,MSL3,GPER1,GUCY1B1,LIG4,LSS,NFYA,MINDY2,SPTB,NXT2,ASTN2,FBXW11,GPR161,TK2,WNT7A,ZNF711,SEMA3B,FZD3,PHTF2,DPF3" Drug 3817_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "SEMA6A,LTBP4,AMPH,APAF1,APC,AQP6,ASPA,ADGRB3,CACNA1G,C5,NRXN3,ABCG1,SNCAIP,DTNB,EDIL3,EDNRA,MBNL2,ETV1,PIPOX,NRN1,FGFR1,SIGLEC8,SRCAP,CNTRL,GRM2,GRM8,SOX21,HLF,C2orf72,KCNN1,KITLG,ADAM22,NF1,NPTX1,NRCAM,P2RX7,CNKSR2,LIMCH1,CHST8,FLRT2,ZNF225,PHTF2" Drug 7520_DN Ald1.1-H_000455; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "MTUS1,APAF1,PPP4R4,SCAPER,CBFA2T2,MAGI1,TAOK2,NRXN3,CNTFR,NCOR1,PDE4DIP,SPOCK2,EXOG,EGFR,TUBD1,ANKFY1,PDLIM5,OGA,COPS8,GLYR1,GNG4,KPNA5,MBD1,MIA2,NF1,OPRL1,PLXNB1,LRP12,MAPK9,PTPRN2,PID1,PPP4R3A,FAM214B,KDM4D,ELMO2,DOP1A,PLCB1,DICER1,AP4E1,SSBP2,ZKSCAN5,ZBTB14" Drug 5536_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ABR,ABHD6,ADRA1D,AP2A2,BIN1,APBA2,ATP6V0A1,C2CD2,LRIG1,RIMS2,DCAF4,SEC14L5,JAKMIP2,TMCC2,NRN1,PTK2B,FAM49B,ADAMTS13,ATXN2L,IL12A,LAMA2,MBD1,NFYA,PLEC,STRN3,LRP12,PPARA,SAMD9,CARF,RPS6KA2,SEMA6D,SH3BP2,SLC2A5,HECW1,ZBTB43,CEP68,TAL1,TK2,XRCC4,SLC30A3,MAP3K12,SLC17A7" Drug 1414_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADD2,OSBPL1A,AK2,APBA2,MTMR2,LDLRAD4,CACNA1A,PICK1,AKAP6,C2CD2L,PARD6A,NR1D2,EIF5,IRAK4,ELN,CELF1,ALDH1L1,SRCAP,PCDH17,DIDO1,ADAMTS13,PTPRT,KCNN2,MEF2C,SLC11A2,SETD4,OCRL,CLDN11,P2RX7,SMIM7,MAPK10,CNNM2,BCAS3,C1orf109,DBNDD2,SPTB,TSPYL2,THSD1,VPS13A,FLRT2,WRN,PRDM10" Drug 3790_DN Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-05 1.00E+00 6.64E-04 7.49E-03 42 196 "ADD2,NME5,CDC42BPA,SEMA7A,NRP2,SYNJ1,CBS,RAB26,ARMC8,RCHY1,PDE4DIP,RIMS2,DAPK3,C2CD2L,PRELID3A,GPD2,ELOVL5,ICA1,SHISAL1,SCIN,ITGA7,LAMA2,MAPT,MATN3,NEK1,STRN3,PRPH,RGS4,CSRNP3,PPP4R3A,LIMS2,ZNF334,LIMCH1,SNCA,TSNAXIP1,KDM4C,IQSEC2,ELOVL4,JMJD6,TIAM1,ZNF24,MAP3K12" Drug ctd:D011189 Potassium Chloride CTD 3.59E-05 1.00E+00 6.74E-04 7.60E-03 29 117 "ACHE,ATP1A3,CACNA1A,CACNA1B,CACNA2D1,NRXN3,CNR1,EDN1,EDNRA,EDNRB,PTK2B,FGF1,PPARGC1A,GPD2,GRIN2D,GSTT2,IGF1,KCND2,MAPT,NPY,PKD1,MAPK3,MAPK9,MAPK10,SNAP25,PDZD2,SYN1,SYT5,TPM1" Drug CID000001329 DPCPX Stitch 3.59E-05 1.00E+00 6.74E-04 7.60E-03 29 117 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,APC,SLC4A4,ALDH7A1,CACNA1A,CACNA1B,SPAG9,P2RX6,ENTPD2,LRBA,SLC29A4,LPAR4,GRIN2C,GRIN2D,GRM2,GRM8,KCNJ5,P2RY13,P2RX7,P2RY1,PRKACB,PRKCB,PTPRB,ZDHHC4,P2RY12" Drug ctd:D019287 Zinc Sulfate CTD 3.67E-05 1.00E+00 6.89E-04 7.76E-03 120 741 "VWA5B2,C3orf14,MTUS1,MARCH4,OGT,CADPS,STK33,CHRD,KIF1A,CALM1,CH25H,RGN,SYNGR3,MAGI1,CHGB,NGEF,LY86,RAB26,CNN3,CNTFR,ABCG1,CS,CSF1,SIPA1L1,RIMS2,ZSCAN23,DCAF8,MYEF2,NR1D2,CDON,EDNRB,SEMA3D,FAM13A,EGFR,MBNL2,APC2,RACK1,KAT8,FGF1,FOXO3,FLT1,ATP2C1,ERGIC3,DOT1L,MEGF11,IQGAP2,GDF1,GGT7,GHR,PPARGC1A,BRD8,GLUL,HBA1,TOX2,HMGCR,HSPA1L,IGF1,IL6ST,KCNJ5,AFDN,TAGLN3,NCF2,NEFM,NELL2,NPTX1,PCBP3,SLC11A2,NRCAM,P2RX7,PALM,CNTN3,PDE4A,PDE4B,CYTL1,PFKFB2,PFKFB3,NECAB2,PPARA,PPM1B,PKIA,MAPK3,MAPK7,PRPSAP2,SNRK,PTPRD,PTPRN,RIPOR1,RASGRF1,ZDHHC14,RGS4,RNH1,ROBO1,ROBO2,RPS6KA2,EMID1,RXRA,FNIP1,SMPD3,MRAS,CNKSR2,SNAP25,UNC5B,TROVE2,SEPT8,SYT1,MTCL1,TBL1X,SATB2,DICER1,RIMBP2,IL34,UCHL1,VIPR2,KCNK12,SPIRE1,INTS3,SLC30A4,WNK2,SPATA13,JPH3" Drug 4637_UP Perphenazine [58-39-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.67E-05 1.00E+00 6.89E-04 7.76E-03 41 190 "ADGRF5,SPARCL1,FAM135A,KCNAB2,FUBP1,ARHGEF2,STOML1,CLTB,AKAP7,CTH,EIF5,ETV1,EZH1,CORO2B,ZNF589,FYB1,SRCAP,GNAL,GNG4,GRM8,SOX21,ICA1,MMP16,OGG1,CLDN11,RETREG1,NLE1,PTPRH,RGS4,NEK11,FAM102A,SLA,PKNOX2,ARHGAP26,SYT1,COBL,SYT5,TRIO,SSBP2,VIPR2,PHTF2" Drug 4507_DN Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.67E-05 1.00E+00 6.89E-04 7.76E-03 41 190 "MTUS1,AMT,APBB2,APC,SLC4A4,SCARB1,ARHGAP33,PDE4DIP,CNTNAP2,FCF1,EGFR,EIF5,STX2,ETV1,FGFR1,FAM49B,GCNT2,SPIN1,POLL,FERMT2,MAP4K5,AGFG1,IL6ST,MAP4,PIK3R1,SLC25A36,GSTCD,KIRREL1,SEC14L1,ZFP30,PPP4R3A,BTBD7,SPTB,PRRC2C,TBL1X,DICER1,BHLHB9,XRCC4,TFIP11,KAT6A,FXR1" Drug 5786_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.67E-05 1.00E+00 6.89E-04 7.76E-03 41 190 "ASIC1,TRMT9B,APAF1,PRX,CACNA1I,LARGE1,AKAP12,HDAC9,EDIL3,EGFR,EZH1,F5,GFER,GSTM5,PADI2,SHISAL1,KCND2,KCNH2,KCNJ5,NOVA1,OPRL1,LRRN3,VPS13C,PTX3,NKAIN1,KHDRBS2,RGS4,KCTD17,PKNOX2,SLC12A4,ZC3H13,RBM26,ARC,TCF4,DOCK9,ICAM5,RUNDC3B,RPRM,XRCC4,NAV3,PARP11" Drug 7209_UP Harmine hydrochloride [343-27-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.67E-05 1.00E+00 6.89E-04 7.76E-03 41 190 "CLK4,ADORA2A,AK2,C1QTNF3,APBB2,N4BP2L1,CACNA1A,SRSF11,FOXN3,CREM,GREB1,RASGRP2,EPHB1,CDKL3,FYB1,SESN1,GLYR1,LPAR4,GRM8,AP4S1,LIG4,MGAT3,MSR1,MYCN,ZNF862,PALM,ENPP2,NLE1,SMIM7,STRN3,GSTCD,RPS20,PPP4R3A,BTBD7,ZNF415,DOK5,SAMSN1,PHLDB1,ARHGEF9,ZMAT3,TIGD6" Drug CID000013296 4-ethylsulfonylnaphthalene-1-sulfonamide Stitch 3.69E-05 1.00E+00 6.91E-04 7.79E-03 30 123 "CHRD,HCN2,CALB1,CALB2,RGN,NOG,CNTFR,AKAP5,CRMP1,PARD6A,EDN1,EDN3,EDNRA,EDNRB,ENO2,FOXO3,GFRA2,GRM8,ACOT7,LIFR,SMAD1,NPY,NTRK2,NTRK3,PRPH,RET,SST,SYP,TNS1,UCHL1" Drug ctd:C045362 prochloraz CTD 3.88E-05 1.00E+00 7.24E-04 8.16E-03 53 268 "ACTN1,SRPX,DOC2A,DPP10,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CAMK2B,CAMK2G,CBR1,ABCG2,CRHBP,CSNK1E,KLHL3,DYNC1I1,DPP6,KLHL5,EGFR,ERBB2,ERBB4,FYN,PPARGC1A,FUT10,STMN2,GRIA2,AGBL5,IGF1,LSS,N6AMT1,NF1,NRCAM,NTRK2,ABCB1,RELN,ACSS3,ENOX1,RET,ZFHX4,ROBO1,RXRA,HES6,NLGN1,SLC6A11,SLC12A2,IFT122,UNC5B,MPRIP,STXBP1,SYP,TMEM121,TSC2,IFT88" Drug 873_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.93E-05 1.00E+00 7.24E-04 8.16E-03 39 178 "ABHD6,FZD9,ST3GAL5,SCAPER,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,OPTN,RASGRP2,TAOK3,BAIAP2,FYN,CYP46A1,STON1,RNFT2,MITF,MXI1,NEK1,PCDH9,SERPINI1,PMP22,PKIA,PRPH,RPS6KA2,SH3GL3,SYBU,WDR47,THSD1,ELOVL4,RGL1,STXBP1,HEY1,RUNDC3B,REEP1,SLC30A3,SLC17A7,ITM2C" Drug ctd:C028451 "3,4,3',4'-tetrachlorobiphenyl" CTD 3.94E-05 1.00E+00 7.24E-04 8.16E-03 81 460 "ACADM,ABHD6,ADCY6,AGT,OSBPL1A,AK2,BBOX1,N4BP2L1,ST3GAL5,C5,CA8,RHBDL1,USP2,CHN2,NGEF,FAM189A2,QKI,CNN3,CRY2,GDA,PDE4DIP,PHF14,PITPNC1,RHOBTB1,FAM107B,NR1D2,SLC12A6,DNAJB6,EIF1,EPB41,F5,FCGRT,FECH,FGF1,IQGAP2,DHRS4,GLI2,GPT2,GSTT2,FAM107A,HLF,IDH3A,IL6R,KCNN2,IPO5,SMAD9,GPR155,AQP11,MIA2,NFE2L2,NFIX,NPR2,SETD4,P2RY1,ENPP2,ABCB1,PIK3R1,PPARA,PPP2R5E,MAPK3,MASP1,APTX,ACSM5,KLHL11,CLIP1,RXRA,FNIP1,FAM102A,PEX26,LMBRD1,KDM4B,ERC1,SULF2,ANKRD28,ANKRD12,DOCK9,ENHO,UBTF,AMN1,TTC7A,IFT88" Drug 6988_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,AMPD3,AMT,CFLAR,SCAPER,BAIAP3,TAOK2,EPS15L1,QKI,DBN1,MED12,ENO2,FHL1,OGA,GAD1,INPP5K,AHDC1,RAB30,ADAMTS13,HNMT,IL6R,INPP5B,KCNN1,TAGLN3,NEK1,NTRK3,PLEC,MAPK10,RGS12,CARF,FBXW7,RXRA,MRAS,SYBU,NLGN1,DOK5,UNC5B,ZNF423,TACC1,SLC44A1,ZBTB14,SLC30A3" Drug 2466_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BIN1,CDC42BPA,MPDZ,BMP7,GYG2,BAIAP3,CFAP410,CALB2,THSD7A,SEPT7,LARGE1,CDO1,LHX2,NRG2,NCOR2,ABCG1,SIPA1L1,ARMCX2,SV2B,REEP2,FGF13,ZNF276,GNAO1,TPPP,GRIK5,IL6ST,MAP4,ZDHHC14,SLC11A1,SMARCD3,SNCA,HECW1,SPTAN1,SPART,IQCE,SMG6,PCDHGA10,TK2,CABIN1,ZNF711,ZNF32,SPHK2" Drug 5664_UP Practolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,AK2,SYNJ2,MTMR3,SGCE,LDLRAD4,CFAP410,HAP1,NRXN3,CNTFR,CNTNAP2,RIMS2,SPOCK3,DTNA,EDN1,ETV1,NRN1,FHL1,DCTN2,KHDRBS3,FYB1,FYN,TDRKH,GRIK5,GSN,HLF,SHISAL1,ADAM22,MYT1,PTPRB,ZMAT4,FRMPD1,SLC9A5,ZNF415,TROVE2,PLCB1,DICER1,CHST8,TK2,CHST5,VLDLR,PARP11" Drug 5840_UP Isoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "GAS7,APOC1,CDK10,ALDH7A1,ST3GAL5,SCAPER,SOCS6,PLAA,AKAP7,AATK,GIT2,DBT,MRNIP,RGS17,STX2,ABCA8,DLC1,FER,FGFR1,FHL1,PDLIM5,ERAP1,GLYR1,HSF2,KIF2A,TAGLN3,CNOT4,PCDH9,ENPP2,LRP12,CCDC40,NEK11,AMBRA1,FNDC3A,NLGN1,PPP4R3A,TMCC1,POGZ,TRIM2,UBTF,WIPF1,TFIP11" Drug 3410_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABHD6,LTBP4,AMPD3,BIN1,APBB2,APC,SEMA4G,CFLAR,CAMK2G,SOCS6,TPP1,FAM189A2,CSF1,DCAF8,DAPK3,C2CD2L,SEMA4D,GRIK5,RASSF8,KCNF1,KCNQ3,OXTR,PLEC,MTRF1L,ZSCAN32,C1orf54,RGS12,TCP11L1,PREX2,EPN2,SLC22A4,ZKSCAN3,ZNF423,PHLDB1,PLCB1,EXOC7,KIAA1107,SZT2,PCDHGA10,TK2,VGF,KCNK12" Drug 6829_UP Althiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AMPD3,AMT,APAF1,SEMA4G,PPP4R4,CA4,CACNA1A,SLIT2,COL9A3,RCHY1,NECTIN3,CSF1R,VCAN,MFAP3L,RUSC2,CDON,SHANK1,DOCK2,MBNL2,ERGIC3,ALDH1L1,POLL,GNAL,GPR37,IL6R,SMAD1,ADAM22,NNAT,CLDN11,PDZRN4,RGS4,KLHDC8A,TCP11L1,RASA3,FBXO11,TAL1,SZT2,PCDHGA10,DICER1,FAM155A,SLC17A7,KCNAB1" Drug 7201_DN Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "CDC14B,MARCH3,MPDZ,SYNJ2,ARHGEF1,CRLF1,TAOK2,CREM,LRIG1,GREB1,PPP6R2,C2CD2L,FEM1B,EIF4G2,EXTL2,EZH1,POLR1B,FGFR1,FAM49B,CGREF1,OGA,FYN,GAA,CLASRP,RNFT2,MAP4,MITF,GIT1,PLEC,PPP3CC,TMEM104,SH3BGR,KDM4B,LHPP,TACC1,ANKRD12,SIN3B,TP53BP1,PLPPR2,VGF,TFIP11,GAN" Drug 7502_UP CP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "LTBP4,CDC42BPA,APC,GAS7,HOMER3,CNTNAP2,HDAC9,CDON,DTNA,EDN1,CNNM1,TNK2,FGFR1,FYB1,SYT17,SLC2A6,ATXN2L,TAGLN3,NF1,NFIX,CDK18,PDE4D,POLG,ZSCAN32,TMEM231,ZNF671,FAM192A,FUZ,SLC22A4,IQSEC2,VPS13A,ASTN2,IQCE,SMG6,DNAH7,R3HDM1,CABIN1,FAM155A,LMF1,TFIP11,PLSCR4,ACTR3B" Drug 5960_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ALK,BEGAIN,AMPH,CDK13,DNAH17,ADGRB2,BAIAP3,PLAA,QKI,DAPK3,SPOCK2,PLXNC1,TNK2,PIPOX,ZNF44,TRAF3IP2,GNG4,PRDM5,PADI2,IL12A,KCNJ5,NF1,CDK18,NLE1,POLG,MAPK7,PTPRN2,RGS12,KLHL11,GSTCD,STK32B,HKDC1,SLC2A5,TSNAXIP1,ZHX3,KDM4C,ZEB1,GPR161,VGF,KCNAB1,MPPE1,UBE3B" Drug 256_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABHD6,BRAP,ADRA1D,AMPH,OGT,APAF1,BCL7A,MTMR3,CACNA1I,CFAP410,CD38,LHX2,HOMER3,CNR1,PCYT1B,DCAF8,EXOG,DRP2,EDNRA,TNK2,ENO2,CDKL3,ANKMY1,SMC2,CAMKK2,SEPT9,LILRA2,RNFT2,ATXN2L,IRF8,ITPKB,STMN1,MID1,GIT1,RGS4,FAM214B,ELMO2,CXXC4,CDK5RAP2,IFT122,EXOC7,SPHK2" Drug 7425_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABR,AP2A2,AK2,ALCAM,FAM131A,RIPK1,CLTB,DCAF8,C2CD2L,MED12,SEZ6L2,EDNRA,CELSR3,BAIAP2,SEMA4D,SEPT9,SRCAP,DHX35,NEK1,NFYA,PLXNB1,PRKAR1B,PRODH,WDR25,TMEM231,GTDC1,RPS6KA2,FUZ,SLC6A8,BTBD7,KDM4B,ZBTB43,PHLDB1,PLCB1,CABIN1,LMF1,NDRG4,UPF3A,PCBP4,MPPE1,ST7,KAT6A" Drug 5250_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "FAM131A,CDK13,CFLAR,CACNA1I,BAIAP3,CAMK2B,RCBTB2,SULT4A1,CSF1,DCAF4,SEC14L5,SV2B,EPHB1,PTK2B,OLFM1,FGFR3,KHDRBS3,OGA,GAD1,GLYR1,POLL,GRM8,ITGA7,MX1,NTRK2,PLCD1,LRP12,MINDY2,RGS12,RASA3,HKDC1,OGDHL,KIF13A,HECW1,CDK19,TSPYL2,TBL1X,DMXL2,FLRT2,VGF,WIPF1,XRCC4" Drug 6011_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADORA1,AMPH,BIN1,DDO,CDK13,MARK4,CACNA1G,CAMK2B,WHRN,NECTIN3,HAPLN1,PDE4DIP,DCAF4,MAML1,ELMO1,DTNB,EDNRA,EDNRB,EGFR,VPS13B,SRCAP,HNMT,KCNN1,MAN2A2,MAPT,MYCN,NNAT,RETREG1,MAPK7,GRAMD1C,ZSCAN2,ZDHHC14,SCN2B,RASA3,SLC11A1,SMARCD3,UNC5B,ZNF423,KIAA0930,PDIA2,PLPPR2,ITM2C" Drug 6106_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ALCAM,AMPD3,AMPH,KCNAB2,PPFIA3,CDC14B,HAP1,HIP1R,ARHGEF1,RAB33A,PDE4DIP,CNTNAP2,ARHGEF4,MFAP3L,RUSC2,DMPK,DTNA,F5,ZNF589,SEPT9,SRCAP,GFER,RASSF8,INPP5B,KCNQ3,KPNA5,LIG4,NELL2,MAPK7,WDR25,GSTCD,RASA3,FRMPD1,SLC8A1,SNAP25,KIF13A,TBCEL,WSCD1,DOCK9,VIPR2,ZNF711,NT5M" Drug 4091_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADCY6,BIN1,CDC42BPA,SLC4A4,ALDH7A1,CFLAR,SYNJ2,ARHGEF7,CBFA2T2,HOMER3,CSF1,RUSC2,ETV1,FGF1,FGFR1,CINP,ATP2C1,GLYR1,GPER1,GPR37,MAN1B1,BACH2,JAK2,KIFC3,GIT1,MYT1,MINDY2,RIPOR1,TMEM231,FBXW7,SCN8A,FBXO11,TROVE2,SS18,ASTN2,ZNF34,TK2,TNS1,RUNDC3B,HIRA,LAT2,XRCC4" Drug 7458_UP Cortisone [53-06-5]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "RALGAPA1,ALCAM,AMPH,SCAPER,CACNA1I,FOXN3,LY86,CREM,ARHGEF10,RUSC2,DUSP9,HIPK3,REEP2,ZNF589,TRAF3IP2,SRCAP,GLYR1,RAB30,PRUNE2,SPACA9,ADAM11,MPP2,NF1,NPR2,PCDHGC3,PLCD1,PRKAR1B,GSTCD,TCP11L1,RPS6KA2,SBF1,ZNF821,CCDC88A,SLC11A1,ZHX3,HECW1,UNC5B,PHLDB1,WSCD1,TIAM1,KCNK12,TFIP11" Drug 7009_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABHD6,PLA2G4C,SLC4A4,ADAM23,SYNJ2,GYG2,KYAT1,TAOK2,NCOR1,HDAC4,MFAP3L,DMPK,CELSR3,ING4,FAM198B,PRELID3A,PCDH17,RAB30,GPR75,ADAMTS13,MAN2A2,MAP4,MBD1,SETD4,PLCD1,PLTP,POLG,PPARA,PRKAR1B,GRAMD1C,GSTCD,RBM34,TSNAXIP1,CLASP2,PLCB1,PIK3R5,WBP2,XRCC4,ZBTB14,NDRG4,MAP3K12,ITM2C" Drug 3511_UP Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADRA1D,ADRA1B,AMPD3,DNAH17,LDLRAD4,CFAP410,SEPT7,FOXN3,CSF1,PHF14,RASSF2,DAPK1,SPOCK2,DBT,FGFR1,FYB1,GALC,GCK,ALDH1L1,GRB10,ICA1,C2orf72,IL6R,KCNB1,SMAD1,ADAM22,ZNF862,NOVA2,PCBP3,CLDN11,WDR25,SCN8A,ST6GAL1,PEX26,BTBD7,KDM4B,ZC3H13,ARHGAP26,JMJD6,KIAA1107,WIPF1,ZFP37" Drug 6137_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BIN1,APAF1,APBB2,SYNJ2,SV2B,DTNA,E2F5,EDN3,HIPK3,HEYL,CELSR3,MBNL2,EGR3,RASGRP2,ERBB2,ETV1,FGFR1,AGAP2,IQCG,FLT1,CAMKK2,GFER,PRUNE2,MYT1,BCAS3,ACSS3,KHDRBS2,CRTAC1,RGS12,SH3BGR,ASAP3,EPN2,ARHGAP26,TBCEL,WSCD1,ZEB1,TRIM2,DOCK9,PCDHA5,AMACR,MKRN3,KCNAB1" Drug 6423_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "TRMT9B,APOC1,ARNTL,N4BP2L1,PROM1,SYNJ2,SCAPER,BAIAP3,CA4,CALB1,RCBTB2,RAB33A,PLAA,AKAP7,FAM149A,IPCEF1,RIMS2,SHANK1,DTNA,EDNRB,SEMA3D,F5,ANKFY1,AFF2,MMP16,PCDH9,PTCH1,PTX3,C1orf54,RGS4,ATXN7,FRMPD1,ATP10B,JMJD6,CUX2,TRIM2,PCDHGB6,LAT2,SLC30A3,ADAMTS9,PLSCR4,PHTF2" Drug 3012_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "SYN3,SPARCL1,CDC42BPA,SLC2A11,BMP7,AKAP6,SLC4A8,CRYBB1,NCOR2,SPOCK3,EXOG,EGFR,EIF1,APC2,ARMCX1,DLL3,CHL1,INPP5K,GLI2,SPACA9,KHK,SMAD1,MAP2,MMP16,MX1,NTRK3,PCDHGC3,BEND5,GAL3ST4,SH3BGR,CNKSR2,ST8SIA1,CDK19,TACR1,TAL1,DNAH7,CHST8,TPM2,TRPS1,SSBP2,VSNL1,SLC17A7" Drug 6139_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "APAF1,APC,MARK4,NCOA1,SLC4A4,SGCE,ARHGAP33,RAB33A,TPP1,SH2B1,CRY2,PPP1R16B,ZFYVE16,MBNL2,ANKMY1,ST3GAL6,FGFR1,PCYOX1,FAM49B,ALDH1L1,ADAM28,IL6ST,MAP4,NF1,NINJ2,CCSER2,RETREG1,PLCB2,SNRK,RPS6KA2,CLIP1,ZNF821,AMBRA1,NUBPL,FAM214B,ZNF34,TRPS1,UBTF,LMF1,ZFP37,EMSY,MARCH8" Drug 6453_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADORA1,ATP2B2,N4BP2L1,SCAPER,SGCE,TPP1,QKI,SULT4A1,WHRN,CSF1,RGS6,RIMS2,SPOCK2,DMPK,HS3ST2,EDNRB,RCAN2,VPS26C,DLC1,SIGLEC8,GFER,KIT,MEF2C,MSI1,GPR85,PLCD1,PLEC,PRKAR1B,SEMA6D,PKNOX2,COA1,TSNAXIP1,HECW1,SS18,SYN2,SYT5,HIF3A,DICER1,WIPF1,CLIP2,EMSY,NT5M" Drug 5949_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NME5,EIF4G3,CFLAR,SCAPER,MYRF,CAMK2B,CBS,SCARB1,ARHGAP33,B4GALT6,CABP1,DRP2,AASS,BAIAP2,CGREF1,OGA,FYB1,ERAP1,GLI2,ELOVL5,MITF,MMP16,NF1,NPR2,CEP41,GRAMD1C,BCAS3,PTCH1,TMEM231,DZIP1,LIMS2,SPATA7,ARHGAP26,CEP68,SYN2,EXOC7,SMG6,TRIO,RPRM,ZNF24,ZNF74,HPS4" Drug 1693_UP Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BRAP,AK2,DOC2A,TRMT9B,APC,APLP1,APOC1,SEMA4G,MARK4,FOXN3,SPOCK2,RCAN1,TSPAN5,EIF4G2,HSD17B14,ENO2,DLC1,FGFR1,FHL1,IQCG,ICA1,KCNQ3,MAPT,MGAT3,NF1,NFYA,NNAT,PCDH9,NLE1,MBOAT7,SUPT20H,KIF13A,KDM4C,ST5,PLCB1,TBL1X,CHST8,PIK3R5,VGF,VIPR2,LAT2,PHTF2" Drug 6756_UP Lynestrenol [52-76-6]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "KCNAB2,CDK10,SLC4A4,HAP1,SLC16A4,FOXN3,VAX2,VCAN,MFAP3L,C2CD2L,TENM1,F5,HPCAL4,TRMO,CSPG5,SYT17,ALDH1L1,GNAL,PRUNE2,SHISAL1,KCNF1,KITLG,MT1M,LYRM9,NTRK3,PDE4D,RETREG1,PPARA,PPP1R1A,PRKAR1B,TMEM231,MARCH1,RGS3,RGS12,ZNF334,CEP68,DNAH7,TLR4,RUNDC3B,KCNAB1,KAT6A,JPH3" Drug 3065_DN Primidone [125-33-7]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "C1QTNF1,ANK2,FAM131A,LGR5,ATP2B2,CA12,CACNB4,HIP1R,LARGE1,EPS15L1,NCOR2,PDE4DIP,RUBCN,DGKG,COQ7,F5,DLC1,FER,ALDH1L1,GPD2,STMN2,LIG4,MID1,AFDN,MMP16,TAGLN3,NEFM,NNAT,CNOT4,NTRK2,PDE4D,PILRA,PPP2R2B,LIMS2,SMARCD3,KDM4B,ZSWIM8,SPART,SYN2,TAL1,TRIO,SPHK2" Drug 4668_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,KIF1A,ADGRB2,NRP2,SEPT7,LARGE1,MAGI1,EPS15L1,STOML1,PICK1,RCHY1,CSF1R,SEMA3D,ETV1,ABCA8,FGFR1,FYB1,SIGLEC8,GLYR1,GPR75,STON1,CACFD1,PADI2,KIFC3,LAMA2,PACRG,RETREG1,MINDY2,CNNM2,PTPRN2,CCDC40,ENOX1,RFX2,RGS12,RASA3,SLA,ARHGEF40,COBL,EXOC7,RPGRIP1L,THRA,REEP1" Drug 5773_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "RALGAPA1,NME5,RASL11B,KIF1A,CACNA1I,CAMK2B,CHN2,IQCK,ARMC8,COL9A3,SH2B1,CRMP1,GREB1,SEMA3D,FRY,APC2,CORO2B,HPCAL4,ADAMTS6,ATXN2L,KCNF1,KCNH2,NOVA1,PCBP3,PDE4D,GPR85,PLCB2,PTPRN2,ACSS3,CCDC40,RET,PNMA8A,EMID1,SLC4A3,OGDHL,UNC5B,RBM26,TACR1,DOCK9,TPM1,SLC17A7,KCNAB1" Drug 5780_DN Methantheline bromide [53-46-3]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "SEMA4G,MARCH3,CAMK2B,RCBTB2,PLEKHB1,ARHGEF6,CDC42BPB,VCAN,GPRASP1,ARHGAP24,C2CD2L,DPH1,TNK2,ETV1,ZNF589,DENND2A,SEPT9,PCDH17,NF1,NFIX,NLE1,FSD1,MINDY2,PTN,TMEM231,SBF1,SEC14L1,ZNF821,GALNT10,AMBRA1,ST6GAL1,BTBD7,TROVE2,SYT1,MGRN1,KIAA0930,TIAM1,BHLHB9,LMF1,MAP3K12,HPS4,GAN" Drug 5610_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADCY6,NME5,AMT,FAM131A,CDC14B,CFLAR,GYG2,CBFA2T2,CLGN,PLEKHB1,STOML1,SH2B1,MAML1,DAPK3,ARMCX2,ZNF804A,MFAP3L,DTNA,KAT8,BAIAP2,ALDH1L1,COPS8,GLYR1,CACFD1,MBD1,PLEC,SLC25A23,PRKAR1B,NEK11,RPS6KA2,ABLIM3,DHX30,ARHGEF9,DMXL2,KIAA0930,ZNF34,BEX4,RUNDC3B,ZKSCAN5,FAM155A,PLPPR2,MPPE1" Drug 6378_UP valdecoxib; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADD2,C1QTNF3,APAF1,APBB2,ARRB1,RASL11B,RAB28,ABCG2,SULT4A1,HOMER3,ZFYVE16,LYPD1,SV2B,DNAH9,SHANK1,DTNB,ETV1,DLC1,NSG1,OGA,DISC1,SRCAP,KCNMB4,ICA1,KCNJ5,LSS,MAPT,MATK,MT1M,NRCAM,PFKFB2,SAMD9,PTPRD,PTPRN2,TCP11L1,CPEB3,SLC6A11,MYH15,KDM4B,GPR161,MAP3K12,EPM2A" Drug 4500_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,ALK,SLC4A4,KIF1A,MPDZ,SCAPER,IL33,RAB26,AKAP7,HAPLN1,CRY2,CSNK1E,ARHGAP32,TBC1D5,RGS17,ANKMY1,TMEM8B,SYT17,SEPT9,MSL3,POLL,GPER1,GUCY1B1,LSS,MAPT,ADAM22,TAGLN3,MX1,PLXNB1,GRAMD1C,GAL3ST4,RXRA,FAM214B,BTBD7,NMNAT2,KDM4C,ASTN2,SYNE1,CRTC1,TNS1,ZNF24,PHTF2" Drug 2728_DN Butacaine [149-16-6]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "MTUS1,APAF1,GAS7,ARRB1,NUMB,BACH1,FUBP1,MYRF,RAB33A,PPP1R16B,DTNA,E2F5,HIPK3,EIF1,F5,PDLIM5,OGA,HTATSF1,GNG4,LILRA2,GRIK5,ITGAM,MEF2C,AFF1,AFDN,PLCB2,PMP22,PILRA,PPARA,PTCH1,TCP11L1,MRAS,SLC11A1,TROVE2,CRTC1,ICAM5,TPM1,TRPS1,CLIP2,XRCC4,REEP1,MAP3K12" Drug 3896_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,BIN1,APAF1,KCNAB2,APC,APOC1,CACNA1I,CLDN10,SLC16A4,CDH2,ARHGEF6,DCAF4,NR1D2,C3orf18,VPS13B,LRRC17,RASGRP2,FER,ANKFY1,PDLIM5,GAD1,GLYR1,MSL3,GPER1,KCNN2,L1CAM,SMAD1,PFKFB2,PLXNB1,LRP12,CEP41,PKIA,C1orf54,ZDHHC14,EPN2,FAM214B,ZC3H13,LMO3,ATP10B,UCHL1,HPS4,SLC17A7" Drug 2282_DN Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "LTBP4,DOC2A,GAS7,APOC1,FUBP1,SCAPER,HAP1,CAMK2G,FOXN3,AKAP7,LRIG1,ARHGEF4,MAML1,C2CD2L,GCNT2,SRCAP,POLL,IPO5,MMP16,NPR2,CDK18,PLCD1,SLC25A23,PPP5C,CNNM2,TMEM104,PTN,KLHDC8A,RPS6KA2,ANKRD6,ABLIM3,CXXC4,SMARCA4,SMARCD3,KIF13A,TSNAXIP1,CLSTN2,PLCB1,SZT2,PARD3,SPHK2,TIGD6" Drug 3225_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,CACNA1G,CFAP410,SEPT7,CDH2,ARHGAP33,CHN2,FAM189A2,QKI,COL9A3,RCHY1,RIMS2,MFAP3L,TENM1,VPS13B,PIPOX,REEP2,PTK2B,PRELID3A,SYT17,RUNDC3A,GNG4,INPP5B,KCNN1,MAP4,MMP17,GPR85,PPP2R2B,PPP5C,TMEM231,GTDC1,CPEB3,FAM214B,ZNF334,ZHX3,ARHGAP26,KIAA1107,WSCD1,TCF4,DOCK9,DNALI1,ADAMTSL3" Drug 5091_DN Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "PPFIA3,MADD,KIF1A,ADGRB2,CACNA1A,SOCS6,CREM,ARHGAP24,SPOCK3,EDNRA,HIPK3,FCF1,ETV1,SCML2,IQCG,CSPG5,ERAP1,DISC1,GPD2,TDRKH,GPR37,MATN3,NDP,NF1,NPR2,PPP3CC,MAPK3,PTN,PID1,SBF1,ZFP30,FNDC3A,LIMS2,CAMTA2,KIAA1107,TNS2,PLPPR2,VGF,LMF1,ZNF24,NDRG4,SLC17A7" Drug 2452_DN Vigabatrin [60643-86-9]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AP2A2,SRPX,ALK,AMH,AMPD3,SLC4A4,CFAP410,RAB33A,ARHGEF10,DTNA,PLEKHA1,ING4,TNK2,C3orf18,CDKL3,CD320,ZNF589,AGAP2,ZNF276,POLL,NF1,NINJ2,PDE1C,PLCB2,PRKAR1B,MAPK10,ZCWPW1,RGS3,EMID1,SH3BP2,PEX26,EPN2,SLC11A1,IZUMO4,DDN,TNS2,KAT6B,CDK20,SPHK2,ZNF142,REEP1,EVI5" Drug 6890_UP AH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "RALGAPA1,C1QTNF3,GAS7,APOC1,BCAS1,PPFIA3,SCAPER,ARMC8,COL4A5,SPOCK3,DTNB,MBNL2,ING4,STX2,ERCC2,FGFR1,CGREF1,GLYR1,POLL,KCNMB4,CNTRL,PADI2,ATXN2L,ELOVL5,IRF8,KCNH2,SMAD1,MATK,ADAM22,MSR1,ZNF862,NPY,PALM,PDE4A,PPARA,ZFP30,COA1,KIF13A,TMCC1,DMXL2,CLDND1,MPPE1" Drug 6305_UP Nizatidine [76963-41-2]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,MTUS1,ALK,PKP4,PPFIA3,SHROOM2,PPP4R4,KIF1A,TAOK2,DZIP3,PHF14,ARMCX2,DMD,DTNA,EDIL3,MTSS1L,STX2,EZH1,HPCAL4,FLT1,USP19,KCNMB4,GRIK5,ITPKA,KPNA5,OCRL,POLG,LRRN3,SAMD9,ACSS3,GSTCD,FBXW7,FRMPD1,SLC11A1,ZHX3,PCDHGA10,SLC19A3,CRTC1,TK2,NT5M,EVI5,KCNAB1" Drug 6683_UP Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADCY6,PPFIA4,BCAS1,CDK13,ATP2B2,SLC2A11,NRP2,BMP7,SCAPER,CALB2,DGKI,CRLF1,CBARP,B4GALT6,QKI,CRY2,SUSD5,EDNRA,ENO2,EPB41,DLC1,ST3GAL6,EFCAB2,GLYR1,GPR75,STMN2,GRM8,AP4S1,AFDN,NF1,NNAT,PFKFB4,LRRN3,ELOVL2,ZSCAN32,KCTD17,FRMPD1,ARC,TLR4,ZNF24,SPHK2,GAN" Drug 7388_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "CDC42BPA,KCNAB2,RGS20,CALB2,SLC16A4,CACNA2D2,FOXN3,TAOK2,WHRN,CREM,RUSC2,EXOG,FAM13A,IRAK4,ING4,BAIAP2,SIGLEC8,ZNF276,SHISAL1,FAM69A,ITPKA,CLDN11,PDE4D,RETREG1,SMIM7,PPARA,PTPRN2,EMID1,ASAP3,TSNAXIP1,IQSEC2,ARHGEF9,ASTN2,DOCK9,TK2,ZKSCAN5,WIPF1,XRCC4,SEMA3B,KCNAB1,PLSCR4,UBE3B" Drug 2892_DN Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "C1QTNF3,APC,MPDZ,CA12,NECTIN3,PPP6R2,DAPK3,MFAP3L,C2CD2L,SLC12A6,KAT8,FHL1,B4GALNT1,MSL3,HNMT,TJAP1,INPP5B,KCNH2,MITF,MMP16,MPP2,LYRM9,NF1,NTRK2,PLCD1,MAPK10,ZDHHC14,RGS3,EPN2,CXXC4,LIMCH1,RBM34,SPTAN1,TSPYL2,SPART,TROVE2,TTBK2,CRTC1,TK2,REEP1,DNALI1,RNF170" Drug 3467_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AK2,GAS7,PLA2G4C,ATP2A2,CFLAR,LDLRAD4,CAMK2G,CBFA2T2,ARHGEF2,SLC4A8,CRMP1,GREB1,DCAF8,ERBB2,FHL1,CAMKK2,OGA,ZNF44,GAD1,GRB10,IL6R,IL6ST,KCNH2,MGAT3,KITLG,MMP16,ADAM22,ZNF862,STRN3,LRP12,PRODH,GTDC1,SLC25A36,SBF1,FAM214B,BTBD7,SPTAN1,DIP2A,PLCB1,TRIO,REEP1,GDPD5" Drug 7003_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASPHD1,NDRG3,ADRA1D,ARRB2,NCOA1,MAGI1,CACNA2D2,SLIT2,EPS15L1,CNNM1,EIF5,ENO2,DOT1L,GFER,MALT1,GLYR1,SLC2A6,KCNH2,MAN2A2,MBD1,GIT1,NPTX1,RETREG2,MAPK7,PTN,NEK11,SBF1,ZKSCAN3,MAPKBP1,UNC5B,SPTAN1,TACC1,EXOC7,ZNF34,TPM1,RUNDC3B,ZNF45,ZNF74,SLC30A3,GDPD5,SEMA3B,ST7" Drug 3438_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADCY6,DOC2A,BIN1,APC,APOC1,PPFIA3,ADAM23,SYNJ2,CACNA1I,LDLRAD4,SOCS6,TPP1,DZIP3,DCAF4,DCAF8,HDAC4,DTNA,GLYR1,RAB30,MSL3,POLL,CNTRL,INPP5B,KCNN2,MIA2,KITLG,PALM,RETREG1,PLEC,PLTP,PLXNB1,PRKAB2,MAPK7,PTPRE,PEX26,FAM214B,IQSEC2,SLC44A1,SPHK2,DNALI1,MARCH8,UBE3B" Drug 4631_UP Josamycin [16846-24-5]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADCY6,SEMA6A,APBB2,CDK10,KSR1,RUNX1T1,SLC16A4,TAOK2,RAB28,AKAP6,PDE4DIP,C2CD2L,EXOG,DRP2,DTNA,COQ7,RASGRP2,ETV1,SIGLEC8,RUNDC3A,GPER1,SPACA9,TJAP1,KCNN1,PACRG,AFF1,CNOT4,NTRK2,CLDN11,PCSK5,SNRK,RFX2,SCN8A,FUZ,ANKRD6,ZKSCAN3,OGDHL,ARHGAP26,TROVE2,PHLDB1,PCDHA5,TRIO" Drug 2795_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "RALGAPA1,ALK,DOC2A,APLP1,PLA2G4C,BACH1,GYG2,CACNA2D1,CBFA2T2,ARHGAP33,RCBTB2,ASIC3,AKAP7,CRMP1,ARHGEF10,CNTNAP2,PHC2,HIPK3,PLXNC1,ENO2,STX2,EZH1,OGA,SIGLEC8,GPD2,KCNQ3,KITLG,ADAM22,NF1,RGS3,RGS12,KCTD17,EMID1,RXRA,FUZ,LIMCH1,TMCC1,SPTAN1,KIAA1107,DOCK9,DICER1,CABIN1" Drug 2638_DN Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "DOC2A,BIN1,APOC1,ST3GAL5,CAMK2B,PLEKHB1,EPS15L1,PLAA,SLC4A8,DTNA,FER,AGAP2,SYT17,SRCAP,POLL,CNTRL,BTN2A1,HNMT,JAK2,LIG4,MAP4,MATK,NF1,NFYA,SETD4,RETREG1,PTPRE,CEP97,ZDHHC14,ZNF821,ELMO2,SOX3,CLASP2,ARHGEF9,ZNF34,TK2,CABIN1,TRIO,VAV1,VGF,TFIP11,RNF146" Drug 5751_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,ADRA1D,AP2A2,ARNTL,KYAT1,CBFA2T2,B4GALT6,LHX2,HAPLN1,CSF1,MFAP3L,SGSM2,TOM1,MRNIP,RRAGB,EZH1,CGREF1,SRCAP,GPR37,GUCY1B1,MPP2,MT1M,NF1,NPR2,RETREG1,GRAMD1C,PTPRE,PTPRN2,RIPOR1,GSTCD,RPS6KA2,ASAP3,SLC14A1,IFT122,SAMSN1,TNS2,GPR161,UGT8,LMF1,MAP3K12,VPS35L,RNF146" Drug 6714_UP Hesperidin [520-26-3]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADGRF5,SPARCL1,SEMA6A,LTBP4,DOC2A,PRX,N4BP2L1,ADAM23,CACNA1I,BAIAP3,LDLRAD4,CAMK2B,LARGE1,CRLF1,TAOK2,ARHGAP22,CSF1,ERC2,EDN3,TNK2,DLC1,FGFR1,GNAL,STON1,AP4S1,ITGA7,SMAD1,ADAM11,ADAM22,NOVA2,RETREG1,PPP1R1A,CRTAC1,KLHDC8A,PNMA8A,GSTCD,RPS6KA2,STUM,HECW1,TACR1,TLR4,REEP1" Drug 4475_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASPHD1,ADD2,LTBP4,APBB2,ADAM23,NRP2,KSR1,KCNAB3,ARHGAP22,NRXN3,STOML1,NCOR2,DTNA,PIPOX,DLC1,SCARA3,AGAP2,FLT1,FOLR2,ERAP1,GRIK5,CACFD1,KITLG,P2RY13,NELL2,NPY,PCBP3,TREM2,PLCB2,KHDRBS2,SCN2B,CNKSR2,SLC11A1,ZSWIM8,HECW1,ZNF423,NFASC,PHLDB1,DOCK9,CHST8,VAV1,VIPR2" Drug 4560_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "TRMT9B,BIN1,PKP4,APC,CDC14B,BAIAP3,CBFA2T2,CACNA2D2,NRXN3,AKAP7,NRG2,PDE4DIP,CNTNAP2,RUSC2,TMCC2,EDNRA,PLXNC1,AASS,TNK2,CDKL3,ANKMY1,FKTN,CINP,PRELID3A,GPR37,SHISAL1,IL12A,MEF2C,MX1,MYO7A,SUGCT,DCUN1D2,RXRA,ATXN2,DZIP1,SLC4A3,SNCA,IQSEC2,PHLDB1,KIAA1107,SLC44A1,TNS1" Drug 5953_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,ADORA1,ADORA2A,NME5,AK2,ALCAM,AMH,CACNA1I,DAPK3,SLC12A6,DTNA,TOM1,EGFR,EGR3,EIF5,HSD17B14,IGSF6,SCML2,DLC1,FGF13,INPP5K,RAB30,GNG4,KCNN1,KHK,P2RY1,PALM,PLTP,NECAB2,PPP2R2B,TCP11L1,RPS6KA2,SLC9A5,SLC11A1,SLC22A4,KIF13A,ZHX3,PHLDB1,MTCL1,TBCEL,FAM189A1,NT5M" Drug 2992_DN Roxithromycin [80214-83-1]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "APBB2,RIPK1,CFLAR,KSR1,CACNA1A,CACNB4,SLC16A4,SCARB1,SOCS6,CHRNA4,B4GALT6,RUBCN,DBT,KIAA0753,TOM1,E2F5,PLXNC1,C3orf18,ST3GAL6,ZNF589,EFCAB2,CAMKK2,NCKAP1L,ELOVL5,ICA1,LSS,MAP4,GIT1,NINJ2,PLEC,PTCH1,RGS3,TCP11L1,CLIP1,FRMPD1,ARFGAP1,SNAP25,EXOC7,TBL1X,TCF4,R3HDM1,REEP1" Drug 202_UP raloxifene hydrochloride; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,BRAP,AK2,ALCAM,CDK10,ARNTL,CFAP410,SLIT2,LHX2,CNTN1,NCOR1,DZIP3,PPP6R2,DAPK3,GIT2,DBT,BAIAP2,PCYOX1,TRMO,MALT1,PADI2,ADAM22,NF1,CNNM2,ZSCAN32,RBBP6,REV3L,CCDC25,ZNF331,SEC14L1,SH3BGR,CHD9,ELMO2,IFT122,TMCC1,TRIM2,TEK,TSN,WIPF1,ZNF142,ZFAND5,MAP3K12" Drug 7148_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BIN1,ALDH7A1,CFLAR,SCARB1,HOMER3,WHRN,ABI3BP,NRG2,HAPLN1,VCAN,CNTNAP2,LYPD1,DTNA,EDNRA,OPTN,AASS,DENND4A,CDKL3,ETV1,SCARA3,TRMO,TRAF3IP2,SEPT9,GLYR1,TDRKH,GUCY1A1,ELOVL5,HSF2,MN1,ZNF862,MAPK12,SH3BP2,FUZ,FNDC3A,PPP4R3A,OGDHL,TRIM2,TPM2,TRPS1,WNT7A,EVI5,MPPE1" Drug 5828_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "APC,SLC4A4,BACH1,NRP2,PCYT1B,IPCEF1,VCAN,ZNF337,DAPK3,GIT2,ETV1,CORO2B,FGF1,TRMO,JAK2,LIG4,NLE1,SLC25A23,SEPT4,PRKAR1B,FAM184A,SUGCT,GSTCD,NEK11,CSRNP3,MRAS,RASA3,FNDC3A,ELMO2,LIMCH1,SNCA,SS18,KIAA1107,HIRA,UBTF,VGF,WIPF1,TFIP11,EVI5,NAV3,SLC17A7,EPM2A" Drug 2858_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,APBB2,GAS7,APLP1,PLA2G4C,PDE8B,SLC4A4,CFLAR,CACNA1I,LDLRAD4,PTBP2,SPAG9,SYNGR3,FOXN3,ARHGEF6,PICK1,CSF1,VCAN,DGKG,TMCC2,ERCC2,FYB1,TMEM8B,GCNT2,GNG4,GRM8,KCNH2,MAPT,MITF,MSR1,ZNF862,RAD51D,EMID1,KCNIP1,SOX3,ZNF423,SAMSN1,HEY1,TK2,WBP2,CLIP2,LAT2" Drug 4233_DN Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "APC,APOC1,CDK10,ARRB2,CDK13,CAST,CREM,ENTPD4,PDE4DIP,CNTNAP2,DTNA,PLXNC1,IRAK4,TUBD1,ETV1,ANKFY1,CINP,FYB1,RUNDC3A,IL12A,ITGA7,KCNN1,MX1,CNOT4,PALM,PCDH9,PLCD1,RGS4,SUGCT,FUZ,FNDC3A,KANSL3,DOK5,SS18,RPGRIP1L,THRA,TIAM1,TMPO,XRCC4,ZNF711,SEMA3B,KCNAB1" Drug 5106_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "TRMT9B,APC,RUNX1T1,ENTPD4,CSF1,PYGO1,RUSC2,PLXNC1,RASGRP2,NRN1,CORO2B,FAM49B,FYN,GRIK5,GSTM5,TJAP1,KIT,MAPT,MMP16,NPR2,NPTX1,PCBP3,ENPP2,GPR85,MINDY2,MAPK7,SNRK,C1orf54,RGS12,RPS6KA2,SLA,ZNF667,SNCA,TMCC1,SPTB,DDN,SYT5,SMG6,TMEM121,TK2,AMACR,SPHK2" Drug 6708_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADGRF5,AMPH,APAF1,DDO,PPP4R4,ARHGDIG,KSR1,BAIAP3,CFAP410,CACNA2D1,CBS,CACNA2D2,NRXN3,CSF1,CTH,RIPOR2,DAPK3,MYEF2,MFAP3L,DLC1,ALDH1L1,GRIK5,SHISAL1,ITPKA,ADAM22,MT1M,MYH3,NRCAM,PFKFB4,CNNM2,PTPRH,CRTAC1,RGS4,RNASEL,RPS6KA2,SLC11A1,SYT1,COBL,TNS1,VIPR2,KCNAB1,GAN" Drug 5741_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AP2A2,BIN1,APC,APLP1,CDK13,SLC4A4,ASIC3,SULT4A1,ENTPD4,ZNF804A,RUSC2,SGSM2,COQ7,CSPG5,GCNT2,ZNF276,GNG4,GPD2,HSF2,JAK2,KCNH2,MAPT,ADAM22,MT1M,ZNF862,NEK1,PFKFB2,SERPINI1,RETREG1,PPARA,MAPK7,RGS4,SMARCD3,IFT122,SNCA,TROVE2,CEP68,JMJD6,KIAA1107,CABIN1,LMF1,EVI5" Drug 3411_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "RALGAPA1,ABR,C1QTNF3,SRPX,APOC1,PDE8B,MARK4,TAOK2,CRMP1,CSF1,CTH,MAML1,DAPK3,MFAP3L,RUSC2,RCAN1,HSD17B14,ERCC2,FAM198B,FGFR1,GLI2,MSL3,TDRKH,GRB10,GSN,INPP1,KHK,MIA2,KITLG,POLG,ZDHHC14,RGS12,TMCC1,PHLDB1,EXOC7,IQCE,XRCC4,SPHK2,REEP1,ITM2C,ST7,RNF170" Drug 5866_UP Estriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADD2,GAS7,CACNA2D1,ARHGEF10,VCAN,PDE4DIP,SPOCK2,MFAP3L,DNAH9,TOM1,MBNL2,AASS,LRRC17,TDRKH,LILRA2,LPAR4,GPR37,KCNF1,MMP16,MX1,NF1,PFKFB2,NLE1,PLCD1,MAPK7,PID1,GAL3ST4,RFX2,CARF,NEK11,FRMPD1,SLC4A3,FAM214B,SLC11A1,ELMO2,RBM34,CEP68,THRA,R3HDM1,HPS4,FAM13C,DPF3" Drug 5697_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BIN1,APOC1,ARRB1,CA4,KYAT1,CLGN,BAG4,SIPA1L1,DZIP3,CTH,DAPK3,GIT2,LYPD1,DTNA,ING4,MALT1,POLL,CNTRL,LIG4,MAP4,KITLG,MITF,ADAM22,NFYA,ZSCAN32,CEP97,NEK11,FBXW7,MAP6D1,ASAP3,FUZ,EPN2,BTBD7,SLC22A4,THSD1,CEP68,ARHGEF9,KIAA0930,THRA,XRCC4,EVI5,ACTR3B" Drug 5388_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AP2A2,APBA2,MPDZ,BAIAP3,CACNA2D2,CHN2,FAM189A2,CPS1,FAM169A,DGKG,DMPK,EDNRA,DLC1,FHL1,ALDH1L1,RAB30,GNAO1,ADAMTS13,RASSF8,ITGA7,KCNN1,ADAM22,MYO7A,CLDN11,TMOD2,PFKFB2,LRP12,PTN,PTPRE,KCNIP1,ZNF821,SLC2A5,SMARCD3,SNCA,PEG10,ZNF423,ARHGEF9,HEY1,VIPR2,EVI5,KCNAB1,ITM2C" Drug 542_UP SC-58125; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,ADORA2A,AP2A2,APBB2,EIF4G3,N4BP2L1,NRP2,SYNJ2,KYAT1,TAOK2,TMEM184B,MAP4K4,CSF1,SOCS5,RIMS2,SPOCK2,BRINP1,C2CD2L,DTNA,FRY,FAM13A,IRAK4,IGSF6,ZNF589,FLNC,AFF2,ATP2C1,CELF1,CACFD1,PTPRT,POLG,MAPK3,DCUN1D2,SH3BP2,ST6GAL1,DZIP1,CDK19,NSFL1C,TBL1X,TCF4,WRN,HPS4" Drug 5778_DN Ebselen [60940-34-3]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABHD6,ADD2,AP2A2,C1QTNF1,BIN1,AMT,PPFIA3,CDK10,PDE8B,CAMK2B,SLC25A14,CPS1,CREM,CSF1R,PDE4DIP,SLITRK5,DPH1,EGFR,MRNIP,PCDH17,SHISAL1,TJAP1,KHK,MATN3,MINDY2,PTPRN2,MCMBP,CCDC88A,BTBD7,TROVE2,RGL1,PLCB1,COBL,IQCE,TCF4,TK2,TNS1,SSBP2,FAM155A,LMF1,ZNF74,KAT6A" Drug 5113_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BRAP,MTUS1,APBB2,MARK4,ALDH7A1,ARHGEF7,FUBP1,CACNA1A,SCARB1,CREM,PDE4DIP,EDIL3,EDNRA,CNNM1,MBNL2,VPS26C,FGF13,ERAP1,TMEM8B,PRRC2B,RASSF8,SCIN,KCNN1,LIFR,MEF2C,NF1,STRN3,KLK6,ZSCAN32,ZNF671,ASAP3,WDR37,SLC14A1,BTBD7,SMARCD3,ZNF415,ZBTB43,EXOC7,TK2,BEX4,ZNF74,AAAS" Drug 2518_DN Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG3,NDRG2,AP2A2,BIN1,CFLAR,SYNJ2,C5,TPP1,HOMER3,SIPA1L1,RUBCN,ARHGAP32,C2CD2L,SUGP2,RASGRP2,PRKAG2,GAA,USP19,GRM8,INPP5B,MEF2C,MGAT3,MITF,NNAT,LRRN3,TMEM231,CEP97,GSTCD,DZIP1,ZKSCAN3,KDM4C,ARHGAP26,TROVE2,SS18,JMJD6,PLCB1,TNS2,FLRT2,VIPR2,XRCC4,SH3GLB2,HPS4" Drug 3820_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,AGT,ADGRF5,AMPH,CDK10,ATP2B2,RUNX1T1,RAB33A,STOML1,SULT4A1,NCOR2,INTS1,DTNB,SRPK3,ELN,EIF1,LRRC17,MTSS1L,IGSF6,FGFR1,FGFR3,AGAP2,PDLIM5,ZNF44,CPLX2,PRUNE2,TPPP,MSI1,NCAM2,NF1,PCBP3,RETREG1,TMEM255A,KHDRBS2,RGS12,CNKSR2,COBL,PCDHA5,TK2,TPM1,TUBB1,SLC17A7" Drug 3622_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,AP2A2,LTBP4,BEGAIN,APBB2,CFLAR,LDLRAD4,ARHGEF1,SLIT2,STOML1,PDE4DIP,SEC14L5,DMPK,DTNA,ZNF589,ALDH1L1,COPS8,MSL3,GSN,MAP4,MMP17,NPTX2,SERPINI1,PRKAR1B,RELN,PTN,ZSCAN2,FAT4,KCNIP1,SH3BP2,SLC2A5,BTBD7,SNCA,ARHGAP26,SPTAN1,RGL1,EXOC7,TBCEL,DOCK9,PLPPR2,WIPF1,MAP3K12" Drug 1682_UP Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ABHD6,APBA2,APBB2,APC,GAS7,BCAS1,SYNJ2,CFAP410,RAB33A,HOMER3,PICK1,NECTIN3,PDE4DIP,CYBB,DMPK,FEM1B,EIF4G2,BAIAP2,INPP5B,KCNB1,MAP4,NF1,NFYA,CNOT4,PALM,CDK18,KCTD15,PLCD1,PMP22,CCDC40,TRIM68,EMID1,FNDC3A,PKNOX2,KDM4C,JMJD6,SMG6,KAT6B,ZKSCAN5,VIPR2,REEP1,KCNAB1" Drug 3132_DN THIP Hydrochloride; Down 200; 22.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "BIN1,APBB2,APC,SCARB1,IQCK,CREM,DGKG,SPOCK2,ECM2,ERCC2,PTK2B,FHL1,NBEA,CSPG5,GAA,SEPT9,GLYR1,POLL,TJAP1,IL6ST,KIT,MAP4,N6AMT1,NINJ2,NPR2,OXTR,PDE4D,SLC25A23,CNNM2,ZSCAN32,PID1,RPS6KA2,RASA3,CPEB3,FBXO11,MYH15,TMCC1,ARHGAP26,EXOC7,CLIP2,ZNF225,NT5M" Drug 3217_DN Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "OSBPL1A,APBB2,APLP1,FAM131A,EPS15L1,SH2B1,C2CD2L,DNM1,CDON,EIF4G2,HSD17B14,MTSS1L,STX2,ANKFY1,CGREF1,INPP5K,SRCAP,POLL,ATXN2L,HNMT,DHX35,KCNQ3,MAP4,GIT1,CNOT4,PCDH9,PDE4A,CCSER2,RETREG1,PLXNB1,RGS12,ARFGAP1,KDM4C,IQSEC2,PCDHA6,TIAM1,CDK20,RPRM,VGF,MAP3K12,EVI5,SEMA3B" Drug 4075_UP Metrizamide [31112-62-6]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "AGT,AMPH,ANK2,GAS7,ARHGDIG,ZSCAN18,BACH1,ADGRB2,RGS11,CAMK2B,CCK,USP2,SLC16A4,SYNGR3,ENTPD2,DLGAP1,FAM189A2,NCOR2,CSF1,RIMS2,SPOCK3,EDN3,AASS,OLFM1,ADAM28,POLL,GNAO1,GNG4,ADAM22,NRCAM,ENPP2,C19orf57,CNKSR2,MYH15,SNCA,ZSWIM8,SPP1,DDN,TAL1,TRIM2,TLR4,TPM2" Drug 5825_UP Ursolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ASIC1,ATP1A3,NRP2,CFAP410,LARGE1,CNOT8,IQCK,COL9A3,CREM,ARHGAP24,BRINP1,GIT2,KIAA0753,CDON,DTNB,FCF1,OPTN,STX2,ERAP1,SYT17,ALDH1L1,POLL,GSTM5,KIF5A,LIG4,MAN2A2,NEK1,NTRK2,PPP5C,RAD51D,FNDC3A,SNCA,TMCC1,TSNAXIP1,ZHX3,IQCE,DOCK9,BEX4,VAV1,TFIP11,CIAPIN1,EPM2A" Drug 6284_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADD2,OGT,PPFIA3,BMP7,SCAPER,CACNA1G,CA12,CBS,LHX2,WHRN,VCAN,PDE4DIP,CDON,TOM1,DUSP9,EDN1,MBNL2,AASS,STX2,CORO2B,FGFR1,EFCAB2,TMEM8B,POLL,STON1,LMO2,ADAM22,NF1,PTCH1,PTPRN2,GSTCD,RPS6KA2,SLC9A5,BTBD7,ZHX3,CRTC1,PCDHA5,CHST8,TK2,NR2E1,RIMBP2,VSNL1" Drug 2351_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG3,APOC1,MARCH3,ATP1A3,AZGP1,PROM1,BMP7,CACNA1A,IQCK,MYRIP,CPS1,CREM,CRMP1,CSF1,DAPK3,SPOCK2,TNK2,RASGRP2,ST3GAL6,SIGLEC8,SRCAP,GNAL,GRB10,ATXN2L,ZNF862,NDP,P2RY1,PDE1C,PDE4D,GDPD2,ACSM5,RASA3,NLGN1,KDM4B,SPTAN1,ATP10B,TACR1,DNMBP,SYNE1,DNAH7,THRA,RUNDC3B" Drug 6449_UP Rolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "ADORA1,BEGAIN,APBB2,PPFIA3,PRX,SCAPER,HAP1,TPP1,QKI,WHRN,COL9A3,NRG2,NCOR2,RGS6,CTH,DAPK1,LRRC17,NRN1,F5,PCDH17,GPD2,GUCY1B1,JAK2,KIF5A,MAN2A2,CNOT4,ENPP2,LRRN3,SUGCT,CNKSR2,KANSL3,COA1,LIMCH1,KIF13A,ZNF415,DMXL2,PCDHA6,KCNK12,SLC30A3,PRDM10,KCNAB1,ADAMTSL3" Drug 5605_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-05 1.00E+00 7.24E-04 8.16E-03 42 197 "NDRG2,AMT,APBA2,GAS7,CFLAR,MTMR3,CBFA2T2,CLGN,RCBTB2,STOML1,SH2B1,NCOR1,DOCK4,MED12,OPTN,MBNL2,STX2,FGFR1,OGA,GLYR1,RAB30,TDRKH,HNMT,INPP1,KCNF1,MSI1,NPTX1,APTX,SBF1,SEC14L1,FERMT1,SPART,PLCB1,ASTN2,TBCEL,DMXL2,TRIM2,CLASP1,CRTC1,PARD3,RUNDC3B,SLC17A7" Drug ctd:C482199 "lipopolysaccharide, E coli O55-B5" CTD 4.10E-05 1.00E+00 7.41E-04 8.35E-03 243 1687 "ABR,USP31,PWWP2A,ADRB2,CASKIN1,TBC1D14,WDR35,CC2D2A,ABCD2,LTBP4,PITPNM2,AMH,EPB41L5,BCAS1,USP37,SEMA4G,ZFYVE28,CHRD,NCOA1,ATP2B2,CARMIL3,ADAM15,KSR1,ARHGEF7,MYRF,CACNA1A,CAMK2B,CAST,CH25H,SPAG9,PRC1,ARHGEF25,CBLN1,CD86,ARHGEF1,AP4M1,ARHGEF2,CDC25B,CLGN,NUMBL,CACNA2D2,RCBTB2,RAB28,MAP4K4,COL4A5,COL9A1,MAGED1,COX4I1,IGDCC3,SEC31B,CRHBP,AKAP12,CRY2,CS,CSF1R,PLXNA4,ARHGEF4,CYBB,MYADM,CENPL,KIAA0586,ZBTB24,FBXL5,ALKBH8,DNM1,DMPK,DNAH9,RPS6KL1,SHANK1,RCAN1,TOM1,DNAJB6,ANKRD46,KLHL5,TMTC1,CELSR3,EGFR,MBNL2,RGS17,MTSS1L,GPHN,VPS26C,RASL12,PRMT5,GORAB,TMEM164,PRKAG2,HPCAL4,PCYOX1,SYNCRIP,SLC37A3,POMT1,HVCN1,MEGF11,GHDC,IQGAP2,ERAP1,TMEM8B,GCK,ALDH1L1,GDF9,AHDC1,GGT7,GGT5,GHR,PPARGC1A,RUNDC3A,KDM2B,LILRB4,GPD1,GPD2,TDRKH,STON1,ADAMTS13,ZBTB49,RASSF8,ZHX1,NCKAP1L,SHISAL1,MYLK2,IGF1,KNDC1,KIAA1755,IL12A,ZNF678,INPP5B,NME9,JAK2,KCNH2,KIF2A,PIK3AP1,MAPT,MATN2,MEIS2,KITLG,AFF1,XRRA1,MOV10,THYN1,MX1,NCF2,NEK1,NFE2L2,ALDH1L2,SLC11A2,SMIM11A,NUCB2,SETD4,PCSK5,PDE4B,PDPK1,GNG2,ABCB1,PKM,PLCD1,PLEC,PURG,SH3KBP1,PPP5C,PRKAB2,PRKACB,MAPK3,LAMA1,DEF8,WDR25,PTCH1,ANKHD1,ZIK1,PTPRG,PEX2,QDPR,RDX,RFX3,ZDHHC4,RNASEL,RNH1,LRRK2,CLIP1,RXRA,AP1AR,DGLUCY,SATB1,SHMT2,CHD9,SLC2A5,ARHGEF40,ZNF334,SMARCA4,CDK5RAP2,SNCA,KIF13A,PDZD2,ZSWIM8,SPP1,ZNF423,IQSEC2,DDN,CAMTA2,SSPO,DIP2A,ADHFE1,ZC3H4,SYNE2,SYP,MMS19,TACC1,CAMTA1,TAF6,AGTPBP1,DMXL2,TRIM2,USP22,SZT2,SYNE1,OBSL1,TMEM121,ICAM5,TLR4,R3HDM1,CABIN1,NR2C2,TRIO,SSBP2,VAV1,CCDC14,TBC1D15,VSNL1,WIPF1,XPO1,ZNF23,SPHK2,ZNF142,ZBTB38,ZFAND5,UPF3A,SLC30A4,NT5M,VPS35L,SLC17A7,HRASLS,FZD3,MARCH8,RTN4" Drug 6022_DN Harmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-05 1.00E+00 7.52E-04 8.47E-03 41 191 "TRMT9B,AMH,APBB2,PPFIA3,NCOA1,EIF4G3,ADAM23,MPDZ,ARHGEF7,CA12,VAX2,BAG4,CNTNAP2,DZIP3,MFAP3L,DENND4A,ZNF589,FGF12,FHL1,FYN,POLL,GPR37,HSF2,IL6R,INPP5B,MPP2,OCRL,LRP12,PPM1B,SAMD9,RAD51D,RNASEL,AMBRA1,FBXO11,CXXC4,RCOR3,ZHX3,LHPP,TMEM121,PLPPR2,VLDLR" Drug CID000002284 baclofen Stitch 4.17E-05 1.00E+00 7.52E-04 8.47E-03 41 191 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ATP1A3,SGCE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CCK,CACNA2D2,CNR1,EIF4G2,GPHN,GABBR1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GRIN2C,GRIN2D,GRM2,GRM8,IGF1,KCNJ5,MAP4,NPY,OPRL1,PKD1,RYR3,SLC6A11,SST,JMJD6,TACR1,MLST8,DPYSL5" Drug 7342_UP Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-05 1.00E+00 7.52E-04 8.47E-03 41 191 "NME5,ARHGDIG,MARCH3,BCL7A,BAIAP3,KYAT1,CCNT1,USP2,LRIG1,FAM169A,GREB1,DTNA,MAMLD1,EGR3,EZH1,OLFM1,IQCG,MALT1,RUNDC3A,PADI2,ATXN2L,ELOVL5,JAK2,PALM,SMOX,LRP12,PRODH,RET,RGS12,ZFHX4,FBXW7,ZNF821,SGK1,KIF16B,SYBU,RBM34,KDM4B,SOX3,SPTAN1,AP4E1,CDK20" Drug 4680_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-05 1.00E+00 7.52E-04 8.47E-03 41 191 "AMT,SHROOM2,RGS20,CACNA1G,PLAA,ABCG2,IQCK,ABI3BP,SMARCAL1,ARHGEF10,DCAF4,FAM131B,BRINP1,RHOBTB1,EIF5,IRAK4,CDKL3,AFF2,SYT17,LPAR4,HNMT,MIA2,NF1,PDE4D,SH3TC2,ZCWPW1,BEND5,SUGCT,MCMBP,MAP6D1,FRMPD1,ST6GAL1,SPATA7,DDN,CEP68,ASTN2,TK2,BHLHB9,TST,HPS4,KCNAB1" Drug CID000000738 glutamin Stitch 4.26E-05 1.00E+00 7.68E-04 8.65E-03 81 461 "APAF1,NCOA1,CFLAR,CACNA1A,CACNA2D1,CALB1,HAP1,RUNX1T1,CBS,KYAT1,CD38,QKI,CPS1,CREM,NCOR1,NCOR2,CSNK1E,HDAC9,EARS2,MAML1,DCTN1,MYEF2,SNAP91,MAMLD1,DNAJB6,OPTN,ENO2,HSPA12B,KAT8,PPP1R1B,BAIAP2,AGAP3,FOXO3,AFF2,ST6GALNAC3,GAA,CPLX2,GGT7,GGT5,PPARGC1A,LYVE1,TXNL4A,TCERG1,GLUL,LNX1,GPR37,CIT,KAT7,ATXN2L,KCNN1,KCNN2,KCNN3,LIG4,PACRG,MAPT,MBNL1,PDE1B,POLG,PPP2R2B,MAPK3,MAPK9,PRODH,PRPSAP2,PSMA6,RDX,ATXN7,HSPA4L,SH3GL3,SIRT2,SNCA,NMNAT2,ZNF423,SYT1,SIRT1,KAT6B,UBC,UCHL1,SLC38A1,SLC17A7,KAT6A,JPH3" Drug 1585_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.33E-05 1.00E+00 7.81E-04 8.80E-03 40 185 "AP2A2,APBA2,PPFIA3,SEMA4G,ARRB2,CFLAR,CAST,CD86,CD38,CREM,PPP1R16B,DOCK4,FAM13A,EPB41L2,BAIAP2,MALT1,RUNDC3A,PRRC2B,CACFD1,CLASRP,ATXN2L,KCNN1,CLIP1,SGK1,SH3BP2,FUZ,AMBRA1,SLA,ARHGEF40,CCDC88A,ZSWIM8,SPTB,CDK19,TSPYL2,PLCB1,KAT6B,TSN,FLRT2,PLPPR2,CLDND1" Drug CID005329102 sunitinib Stitch 4.40E-05 1.00E+00 7.86E-04 8.85E-03 31 130 "CLK4,CAMK2A,CAMK2B,CAMK2G,CSF1,CSF1R,DAPK3,EGFR,TNK2,EPHB1,ERBB2,ERBB4,FER,FGFR1,FGFR3,FLT1,CAMKK2,FYN,GFRA2,MAP4K5,MYLK2,JAK2,KIT,PTK2,RET,BAALC,RPS6KA2,SLC12A2,ALG1,TEK,EPM2A" Drug CID000001207 MK-801 Stitch 4.46E-05 1.00E+00 7.86E-04 8.85E-03 57 296 "ACHE,ADORA1,ADORA2A,RGS20,CA4,CACNA2D1,CALB1,CALB2,CAMK2B,CCK,CHRNA4,CNR1,CREM,DBI,GRIN3A,DTNB,EIF4G2,RGS17,ENO2,ERBB4,PPP1R1B,FOLH1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,DISC1,GNAL,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,HBA1,MAP2,KITLG,NF1,NPY,NTRK2,OPRL1,PDE4B,ZDHHC8,PPP3CA,PPP3CC,MAPK3,PRODH,PTCH1,PTN,S100B,DDN,SST,ARC,TACR1" Drug 2753_UP Syrosingopine [84-36-6]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.49E-05 1.00E+00 7.86E-04 8.85E-03 39 179 "ASIC1,LTBP4,PPFIA3,MARK4,N4BP2L1,ST3GAL5,SYNGR3,ARHGEF2,CLGN,RAB26,ARMC8,MFAP3L,DTNA,OPTN,MBNL2,RGS17,HSD17B14,ENO2,STX2,AMOTL2,SRCAP,TDRKH,GRB10,KCNH2,SLC11A2,FA2H,PRPH,TMEM231,ZFHX4,ZNF821,SH3BP2,ARHGEF40,KDM3A,TRIM2,TK2,BEX4,WBP2,VLDLR,SLC30A3" Drug 4619_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.49E-05 1.00E+00 7.86E-04 8.85E-03 39 179 "BIN1,GAS7,FAM131A,C5,WHRN,CREM,AKAP12,HAPLN1,ABCG1,CSF1,CTH,ARHGEF4,DBT,PITPNC1,EDNRA,SPEG,AGAP2,PRUNE2,GPER1,ACOT7,JAK2,MIA2,OPRL1,PDE4B,SMOX,PMP22,FA2H,GSTCD,RTN1,FAM102A,ST6GAL1,PHLDB1,JMJD6,ADGRL3,TBL1X,PCDHGB6,TPM2,SSBP2,KCNAB1" Drug 5086_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.49E-05 1.00E+00 7.86E-04 8.85E-03 39 179 "ADRB2,APAF1,ARNTL,RGS9,ST3GAL5,CACNA2D1,HIP1R,USP2,CHN2,CRY2,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,BAIAP2,FYN,STON1,GUCY1B1,FAM69A,ITGA7,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,TMEM231,ENOX1,RGS4,RPS6KA2,SH3GL3,SLC2A5,ARHGAP26,CEP68,RGL1,SYT1,LAT2,DPF3" Drug 4585_DN Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.49E-05 1.00E+00 7.86E-04 8.85E-03 39 179 "OSBPL8,CDC42BPA,CDC14B,SPAG9,SLIT2,TBC1D5,NR1D2,EGFR,EIF4G1,EIF5,PDLIM5,SPIN1,HTATSF1,FERMT2,AGFG1,IL6ST,MAP4,MBNL1,MBP,MYO6,NEK1,ING3,SLC25A36,SEC14L1,SMARCA4,KDM4B,MYCBP2,PEG10,TROVE2,PRRC2C,TBL1X,ZEB1,TRIM2,DICER1,KAT6B,UBTF,USP1,ZNF24,FXR1" Drug 3130_DN Halofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AMPD3,BIN1,APAF1,APBB2,APC,APOC1,PDE8B,KIF1A,LDLRAD4,CHN2,IQCK,CSNK1E,SIPA1L1,DLC1,FHL1,CSPG5,GAA,ZNF44,ELOVL5,IL6ST,KIT,LAMA2,MAP4,MIA2,AFDN,GIT1,ZNF862,SLC11A2,PDPK1,PLCL1,SLC25A23,PPARA,BEND5,MRAS,CPEB3,CDK19,PCDHGA10,SYNE1,PARD3,NPDC1,ATP6V0E2,TIGD6" Drug 6146_UP Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "BIN1,PROM1,MYRF,THSD7A,HAP1,HIP1R,RUNX1T1,CBFA2T2,SYNGR3,CHRNA4,CABP1,CSF1,RIPOR2,SNPH,PARD6A,DMPK,OPTN,MBNL2,RASGRP2,ERBB2,RASL12,KAT8,FGF1,KHDRBS3,GATM,KCNMB4,PRUNE2,KCNN1,MSR1,PRKAR1B,RELN,KLK6,BCAS3,RET,KCNIP1,FERMT1,SLC11A1,FAIM2,TMCC1,ASTN2,WSCD1,PCDHGA10" Drug 3567_UP Piretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "SYN3,ALCAM,KCNAB2,APC,ARNTL,SLC4A4,SLC2A11,ATP6V0A1,RGS9,CLDN10,CBFA2T2,ARHGAP33,HOMER3,CSF1R,RIMS2,FAM131B,SEC14L5,MFAP3L,HIPK3,C3orf18,ERCC2,ZNF589,GAD1,ERAP1,GPER1,ADAMTS13,KITLG,NFYA,CNOT4,PDE1C,SLC25A23,CNNM2,RGS12,KCTD17,CPEB3,CXXC4,JMJD6,VPS13A,FLRT2,LAT2,UBE3B,SENP7" Drug 5414_DN "Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "OSBPL1A,ALCAM,PPFIA3,ALDH7A1,KIF1A,SLIT2,AKAP7,CSNK1E,SIPA1L1,DAPK3,DBN1,MRNIP,ENO2,EZH1,ZNF589,FGFR1,IQCG,OGA,RUNDC3A,GPER1,GRIK5,INPP1,MAPT,TM6SF1,MIA2,ZNF862,NF1,PLXNB1,RAD51D,RGS3,RGS12,NEK11,RPS6KA2,KIF13A,SPTAN1,VPS13A,SLC44A1,TK2,TPM1,ZNF45,TFIP11,GDPD5" Drug 2786_DN Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,CDC42BPA,APOC1,CDC14B,SCAPER,QKI,SLC4A8,CSNK1E,PDE4DIP,CNNM1,EZH1,ACSL4,ZNF589,MPP6,SYT17,SRCAP,HTATSF1,IL6ST,KCNH2,MITF,ZNF862,SLC11A2,PDE4A,STRN3,MBOAT7,TTC13,MRPS18A,ZKSCAN3,ERC1,TTBK2,PDLIM2,DMXL2,PCDHA6,ZNF34,TIAM1,CDK20,PLPPR2,LMF1,ZNF45,ZNF142,REEP1,HPS4" Drug 4759_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG3,LTBP4,AMPD3,BIN1,APOC1,MARK4,SLC2A11,ARHGEF2,CLGN,TAOK2,PDE4DIP,HSD17B14,DLC1,ZNF589,FHL1,INPP5K,POLL,GNG4,CNTRL,GRM8,ATXN2L,INPP5B,KCNF1,LMO2,MEF2C,MIA2,MYT1,P2RY1,RGS3,ZFHX4,SYBU,BTBD7,DOP1A,ZC3H13,IQSEC2,PLCB1,KIAA0930,PCDHA5,HEY1,PARD3,CDK20,ADAMTSL3" Drug 7270_DN "Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "BIN1,EP400,APBB2,APC,APLP1,ATP2A2,MPDZ,CFLAR,SCAPER,CCNT1,FAM169A,ZFYVE16,SPATA2,SGSM2,STX2,ERCC2,VPS26C,ZNF589,BAIAP2,CINP,FICD,SLC2A6,MAPT,MN1,ZNF862,OGG1,MBOAT7,POLG,PPP5C,ELOVL2,SUGCT,TCP11L1,FAM214B,KBTBD4,IFT122,CDK19,NXT2,AGTPBP1,KIAA0930,OSBP2,MAP3K12,MPPE1" Drug 1482_DN Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABR,NDRG3,AP2A2,APAF1,CDC14B,CDK10,NUMB,KIF1A,C5,SRSF11,CREM,ABCG1,ARHGEF10,PDE4DIP,GIT2,DTNA,SEZ6L2,FEM1B,FECH,CSPG5,MPP6,USP19,MAP4,MPP2,NFYA,PDE4A,PPP3CC,CNNM2,PTPN13,SBF1,ZFP30,FUZ,FBXO11,ABLIM3,TTC17,TROVE2,KIAA0930,ZNF34,BEX4,HIRA,VGF,REEP1" Drug 7215_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA2A,APAF1,APBB2,SEMA4G,RGS11,TAOK2,CLCN3,STOML1,FAM189A2,IPCEF1,RASSF2,GIT2,SLC12A6,STX2,ALDH1L1,GLYR1,GPD2,ADAMTS13,GRIK5,IRAK3,SYNPO,ITPKB,LIG4,MEF2C,MPP2,ZNF862,NF1,PTPRB,KHDRBS2,RGS12,KCTD17,EMID1,SH3GL3,SYBU,PREX2,ZEB1,THRA,AMACR,KCNK12,DNALI1,EPM2A,RNF170" Drug 7270_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADCY6,AMPD3,BIN1,SEMA4G,ARRB2,N4BP2L1,SCARB1,SRSF11,SOCS6,PLEKHB1,HINFP,NCOR2,CNTNAP2,ARHGAP32,DCAF8,GIT2,MFAP3L,VPS13B,FGF13,FGFR1,ZNF274,USP19,GPD1,HLF,TJAP1,LIG4,FA2H,PRKAR1B,KLK6,SH3TC2,ROGDI,SMARCD3,KDM4B,R3HDM1,PARD3,HIRA,WNT7A,XRCC4,MAP3K12,HPS4,PHTF2,ACTR3B" Drug 7267_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,MTUS1,MARK4,SYNJ2,RUNX1T1,NRXN3,VCAN,SLITRK5,ARHGEF4,FAM131B,DTNA,FEM1B,FAM13A,EGFR,RGS17,BAIAP2,TRMO,ZNF274,SRCAP,FERMT2,MUM1,IFI16,TJAP1,IL6R,INPP5B,PDE4D,MAPK3,ROGDI,ROBO1,CSRNP3,SLC9A5,SMARCD3,MYH15,TMCC1,ZHX3,THSD1,ELOVL4,DIP2A,SMG6,NDRG4,HPS4,RNF146" Drug 1532_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,ASIC1,CDC14B,ARRB1,ALDH7A1,BAIAP3,CACNA2D2,CNTN1,ENTPD4,NCOR1,CSF1,CNTNAP2,SPOCK3,TENM1,MTSS1L,PTK2B,DCTN2,GNAL,GPD2,TDRKH,HAS2,TJAP1,IL6R,INPP5B,KHK,KPNA5,MAN2A2,TAGLN3,PCDH9,SLC25A23,CEP97,EMID1,FERMT1,ZBTB43,SYT5,WSCD1,CRTC1,TIAM1,PIK3R5,CHST5,ZFP37,EVI5" Drug 2206_UP Finasteride [98319-26-7]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABHD6,SRPX,BIN1,CDK10,PDE8B,NCOA1,GYG2,CFAP410,CA12,SYNGR3,CHN2,ARMC8,ABCG1,DAPK3,MFAP3L,EDNRA,MBNL2,PLEKHA1,C3orf18,F5,FGFR1,IQCG,ALDH1L1,GPR162,GFER,POLL,IL6ST,KHK,MBNL1,MID1,NNAT,P2RY1,PLCD1,PURG,PMP22,FSD1,KIRREL1,SPTB,PHLDB1,RPGRIP1L,MAP3K12,SLC17A7" Drug 3728_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "C1QTNF3,AMT,APBB2,ATP2A2,CAMK2B,CAST,FOXN3,TAOK2,RAB26,CSNK1E,ARMCX2,HIPK3,IRAK4,ANKMY1,FGF1,POLL,ELOVL5,ICA1,MAP2,MAPT,TAGLN3,NPR2,PDE4A,GPR85,PFKFB2,PPP5C,PRKAR1B,PTCH1,GAL3ST4,ASAP3,SLC9A5,TSNAXIP1,IZUMO4,CEP68,CHST8,R3HDM1,RPRM,ZNF24,TFIP11,MAP3K12,NT5M,TIGD6" Drug 7556_DN vinblastine sulfate; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,ABHD6,NDRG3,APC,APOC1,ARNTL,MARK4,CFLAR,SYNJ1,ARHGEF7,BAIAP3,CBS,CNOT8,CNTNAP2,LYPD1,RHOBTB1,EDIL3,EDNRA,FCF1,IRAK4,CINP,GLYR1,MSL3,HAS2,SCIN,JAK2,MMP16,MPP2,NACA,NF1,PFKFB2,VPS13C,PTN,SBF1,SLC14A1,CDK5RAP2,POGZ,ELOVL4,ARHGEF9,VPS13A,FBXW11,LMF1" Drug 2709_DN Sulfanilamide [63-74-1]; Down 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,ADRA1D,PPP4R4,NUMB,ATP2A2,ATP6V0A1,FUBP1,CLGN,AKAP7,ARMC8,CREM,ENTPD4,PDE4DIP,PPP1R16B,RHOBTB1,CNNM1,ZNF589,KHDRBS3,ERAP1,ZNF276,GNG4,LILRA2,SMAD1,NFYA,CNOT4,SLC11A2,PILRA,POU6F1,PTPRO,MRPS18A,SH3BP2,SLC2A5,SPTB,RBM26,JMJD6,EXOC7,KIAA1107,CRTC1,TK2,TRPS1,SH3GLB2,MAP3K12" Drug 3196_DN Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADRA1D,ALCAM,TRMT9B,PPFIA3,MARCH3,DNAH17,MARK4,NUMB,ATP2A2,CFAP410,CAMK2G,ARHGEF1,TAOK2,PLAA,ARHGEF6,AKAP7,CRY2,CTH,CYBB,BAIAP2,ZNF44,POLL,LPAR4,IPO5,NNAT,CNOT4,WDR25,TMEM231,ZCWPW1,RGS3,RGS12,EMID1,ABLIM3,KIF13A,SOX3,LHPP,ELOVL4,DOCK9,TMEM121,CHST8,ZNF74,EVI5" Drug 4480_UP Dacarbazine [4342-03-4]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AMH,PPFIA4,APAF1,CDK13,ALDH7A1,ADAM23,CFLAR,FUBP1,CFAP410,STOML1,AKAP5,CYBB,EXOG,ING4,RGS17,OGA,FYN,PRRC2B,GRIK5,ICA1,SHISAL1,JAK2,SMAD1,GPR85,MAPK7,PTPRH,PTPRN2,RGS4,KCNIP1,SH3BGR,FBXO11,PKNOX2,ZNF334,SOX15,MCF2L,KIAA1107,TRIO,RUNDC3B,LAT2,SPHK2,ZBTB38,ZNF225" Drug 4090_DN Myricetin [529-44-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADCY6,AP2A2,NME5,ST3GAL5,SYNJ2,LARGE1,NCOR2,TBC1D5,PLPPR4,CHRDL1,DYNC1I1,EDN1,FAM13A,EGFR,IRAK4,STX2,ETV1,IQCG,TDRKH,DIDO1,INPP5B,KHK,KIFC3,NFYA,NPR2,PLCD1,GRAMD1C,ZSCAN32,ZSCAN2,FBXW7,CSRNP3,ATXN7,ZFP30,DZIP1,ARHGEF40,LIMCH1,TROVE2,CRTC1,GPR161,TK2,EMSY,SEMA3B" Drug 6037_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADRA1D,ALCAM,CDC42BPA,APC,EPB41L5,FAM131A,RGS20,ATP2A2,CACNA1I,CAMK2B,FOXN3,SLIT2,PDE4DIP,GREB1,MFAP3L,EDNRA,EDNRB,OPTN,PLXNC1,FGFR1,AGAP2,FYB1,GRIK5,ELOVL5,KCNN2,MGAT3,KITLG,MMP16,MSI1,ZNF862,LRP12,ZFHX4,SBF1,ZNF821,RPGRIP1L,SZT2,PCDHA5,CHST8,WIPF1,REEP1,HPS4,MPPE1" Drug 3364_DN Acetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,APOC1,CFLAR,SYNJ2,SCAPER,RCHY1,ENTPD4,TBC1D5,DMPK,SPEG,ACSL4,IQCG,PRELID3A,OGA,SRCAP,IL6ST,INPP5B,JAK2,SMAD1,MPP2,ADAM22,CDK18,RETREG1,LRP12,PTPRO,CLIP1,RASA3,SLC22A4,RBM34,IQSEC2,TBCEL,SMG6,PCDHA6,BHLHB9,WIPF1,KLC2,ZFP37,ZNF24,SPHK2,REEP1,EMSY,HPS4" Drug 4432_UP "estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADRA1D,SEMA7A,GAS7,CDC14B,MARK4,KSR1,CFAP410,CA8,CA12,KALRN,LDB2,RAB33A,TPP1,PDE4DIP,DTNB,ELN,CORO2B,NSG1,RUNDC3A,GPR37,IRF8,ITGA7,MAN2A2,MATK,MGAT3,NTRK3,ENPP2,PGAM2,PIK3R1,PPP5C,PTPRN2,RNASEL,PKNOX2,ZNF334,SP4,MCF2L,PCDHGA10,TK2,TNS1,UCHL1,VIPR2,ZNF225" Drug 4981_UP Harpagoside [19210-12-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,ABHD6,NDRG2,LTBP4,APBA2,PPFIA3,ARHGDIG,MTMR3,CACNA1I,CAMK2G,CBFA2T2,ARHGAP33,TPP1,HOMER3,AKAP7,CRY2,AATK,RIMS2,SPOCK2,ZNF589,FGF13,GPER1,GSN,RASSF8,KCNH2,MYO9A,NF1,CLDN11,P2RY1,NLE1,CEP41,PRKAR1B,MAPK7,NEK11,TCP11L1,FBXO11,RGL1,ARC,WSCD1,ZEB1,TRPM2,ZNF711" Drug 1671_UP Meticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "APC,MADD,MARCH3,MARK4,SLC4A4,ADAM15,CFLAR,CFAP410,SOCS6,RAB28,TPP1,SH2B1,ARHGEF4,MFAP3L,RUSC2,CDON,VPS13B,NCALD,DLC1,IQCG,ALDH1L1,GRB10,ATXN2L,MAP4,MATK,MKLN1,MMP17,MYO9A,NF1,CNOT4,PGAM2,PLCD1,POLG,SLC2A5,PPP4R3A,DOK5,ARHGAP26,EXOC7,TRIM2,TPM1,LMF1,NDRG4" Drug 1538_DN Danazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG2,SLC4A4,SCAPER,CAMK2G,CBFA2T2,SULT4A1,CREM,DAPK3,GIT2,NR1D2,FCF1,EGFR,DENND4A,ACSL4,SCML2,PRELID3A,CSPG5,GLYR1,CNTRL,GRB10,RNFT2,MITF,NFYA,SLC11A2,WDR25,TMEM231,NEK11,SEC14L1,ZNF821,SH3BP2,ANKRD6,PPP4R3A,MAPKBP1,ELOVL4,CEP68,ARC,ASTN2,IQCE,FBXW11,VGF,SPHK2,UBE3B" Drug 7488_UP ST021200; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "KDM5D,LTBP4,APBB2,RGS20,AZGP1,HAP1,COL9A3,MFAP3L,RUSC2,DOCK2,DTNB,FEM1B,ING4,FCGRT,ZNF44,ALDH1L1,GNAO1,LPAR4,GPER1,PCLO,FAM107A,KCNJ5,KITLG,MYT1,NELL2,PDE4D,PTPRD,TCP11L1,KCNIP1,SLC4A3,FAM214B,CCDC88A,BTBD7,HECW1,SPP1,SPTB,ATP10B,VPS13A,TK2,CHST5,KCNK12,XRCC4" Drug 5673_DN Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADRA1D,BIN1,APOC1,CA4,PLEKHB1,TAOK2,FAM189A2,AKAP7,CSNK1E,DAPK3,ARMCX2,RCAN1,ANKMY1,FAM198B,CGREF1,GALC,MALT1,GLYR1,ACOT7,HNMT,IPO5,LIG4,LMO2,MMP16,ADAM22,PDE4A,SMIM7,PRODH,ELOVL2,GSTCD,MAPK12,PEX26,CDK5RAP2,KDM4B,PDLIM2,RPGRIP1L,AP4E1,SLC44A1,RPRM,PLPPR2,REEP1,GDPD5" Drug 2369_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABHD6,NDRG2,SEMA4G,PPP4R4,MARK4,KSR1,ARHGEF7,MTMR3,FOXN3,CHN2,COL9A1,CREM,SH2B1,RCAN1,EDNRB,HEYL,COQ7,CDKL3,FHL1,PDLIM5,GLYR1,SPACA9,TJAP1,LAMA2,NNAT,PNMA3,CNNM2,RIPOR1,ZFP2,FRMPD1,CXXC4,ATP10B,WSCD1,DMXL2,DOCK9,TNS2,TEK,CDK20,TRO,ZNF32,SPHK2,KCNAB1" Drug 5409_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG2,ALCAM,AMPD3,GAS7,CDK13,N4BP2L1,NRP2,CALB2,CAMK2G,KRIT1,ARHGEF1,VAX2,CNTN1,AKAP7,ABCG1,DCAF4,GSDME,EDNRB,TENM1,COQ7,DLC1,HPCAL4,POLL,CNTRL,RASSF8,JAK2,KCNH2,KCNN1,LIG4,MAP2,MAPT,MPP2,MSR1,PLCD1,CEP41,MAPK10,ZNF493,FBXO11,PLCB1,DMXL2,PCDHGA10,MARCH8" Drug 6841_DN Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,ABHD6,ADRA1D,AK2,ALCAM,CDC42BPA,GAS7,FAM131A,CFLAR,ARHGEF2,QKI,CTH,GIT2,EXOG,SLC12A6,DTNA,ING4,RRAGB,FGFR1,IQCG,SRCAP,GNG4,TDRKH,GRB10,LIG4,MAP4,MBD1,NFYA,SETD4,MAPK7,PRPH,ZSCAN32,CCDC25,NEK11,SLC9A5,ZKSCAN3,COA1,TMPO,HPS4,SEMA3B,MPPE1,GAN" Drug 7549_UP CP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,LTBP4,PPP4R4,PDE8B,ALDH7A1,ADGRB2,CRLF1,TAOK2,RAB26,CRY2,RUBCN,DAPK3,DPH1,SEMA4D,SRCAP,CACFD1,FICD,TJAP1,SCIN,ITPKA,LIFR,ADAM22,PRPH,SAMD9,WDR25,PTN,PTPRN2,ZCWPW1,ENOX1,SUGCT,EMID1,ASAP3,CCDC92,MYH15,IZUMO4,ARHGAP26,POGZ,ASTN2,DOCK9,TNS1,PLPPR2,PCBP4" Drug 3024_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "SYN3,ABHD6,AGT,BIN1,SEMA4G,PRX,SPTBN4,MYOM1,CA12,CCK,CDO1,CACNA2D2,CHN2,AKAP6,CREM,PDE4DIP,DMPK,PRELID3A,SIGLEC8,ALDH1L1,RUNDC3A,ZNF276,LILRA2,GRIK5,KIFC3,ADAM22,OPRL1,PDE1C,PFKFB4,CCSER2,RELN,RASGRF1,SEMA6D,ASAP3,TMCC1,SP4,IZUMO4,DNMBP,ZNF34,ICAM5,TPM2,LMF1" Drug 1222_UP 2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "MTUS1,AK2,APC,APOC1,PPFIA3,CDK13,STX16,CFAP410,CNOT8,RAB33A,NCOR2,GPRASP1,ARMCX2,SV2B,CDON,EDNRB,CNNM1,FECH,OGA,ALDH1L1,GSN,ICA1,MIA2,MN1,MX1,ZNF862,NELL2,P2RY1,SERPINI1,RETREG1,FXYD1,MAPK3,PTN,CCDC40,RGS4,TCP11L1,SUPT20H,BTBD7,SNCA,SPTAN1,SYT5,EPM2A" Drug 2528_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADRA1D,NCOA1,SLC4A4,ATP2A2,KIF1A,C5,LDLRAD4,CFAP410,CAMK2G,CAST,HOMER3,RCHY1,ZNF337,SPATA2,CDON,FAM13A,PLXNC1,PRKAG2,GAA,SEPT9,LILRB4,SLC2A6,TJAP1,LIG4,ZNF862,MYT1,NF1,NFYA,NNAT,PDE4A,LRRN3,SUPT20H,FRMPD1,SNCA,RBM26,CEP68,JMJD6,EXOC7,SIN3B,TNS2,TPM1,ST7" Drug 4241_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "C1QTNF3,SEMA7A,PKP4,APC,PPP4R4,ATP6V0A1,HAP1,CBS,LDB2,KRIT1,B4GALT6,CSF1,CNTNAP2,PHF14,MAML1,DAPK3,MFAP3L,ECM2,COQ7,NCALD,FGF1,ERGIC3,IQGAP2,NEU3,FAM107A,MAN2A2,PDE4D,RETREG1,MAPK10,CNNM2,PTN,GAL3ST4,RGS4,RGS12,FBXO11,AP4E1,ZNF34,HIRA,LAT2,EMSY,KCNAB1,DPF3" Drug 5886_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ANK2,CDK13,ADAM23,CFLAR,CACNA1G,CA8,ARHGEF2,DCLK1,ASIC3,LY86,CSF1,CSF1R,C2CD2L,EBI3,TENM1,LRRC17,SIGLEC8,SEPT9,GNAL,PADI2,KCNH2,KCNJ5,KPNA5,ADAM22,NNAT,PPP2R2B,LRRN3,CNNM2,BCAS3,GAL3ST4,KLHL11,TCP11L1,DZIP1,SLC4A3,ARHGAP26,TCF4,PCDHGA10,CRTC1,TK2,LMF1,WIPF1,SLC30A3" Drug 3748_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,APAF1,PDE8B,ATP6V0A1,NRP2,SCAPER,CLDN10,DCLK1,SULT4A1,HS3ST2,DRP2,DTNB,HEYL,FGF1,FLT1,ALDH1L1,PCDH17,GRM2,PADI2,ICA1,IL6R,ITGA7,KCNJ5,KCNN1,MARK1,MMP16,MYO7A,NPTX1,PCDH9,PDE1B,FXYD1,PTCH1,PTN,PTPRH,RASGRF1,RGS12,RTN1,PREX2,ZC3H13,MCF2L,NPL,MAP3K12" Drug 4225_UP Carcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ACHE,PKP4,GAS7,CDC14B,NRP2,SYNJ2,GYG2,CACNA1I,NRXN3,COL9A3,CSF1,INTS1,EIF4G2,CALCRL,RASGRP2,BAIAP2,SIGLEC8,SYT17,GCK,PCDH17,GRIN2C,GSTM5,IL6ST,MAP2,PFKFB4,PTPRD,PTPRN2,GAL3ST4,PBRM1,TCP11L1,ZHX3,ZC3H13,NFASC,PLCB1,PCDHA5,AP4E1,ZNF34,TNS1,ZNF225,KCNAB1,EPM2A,JPH3" Drug 4004_UP Boldine [476-70-0]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADD2,ANK2,APBB2,DDO,CDK13,N4BP2L1,FUBP1,CACNA1G,CCK,CHN2,NRXN3,SUSD5,RIMS2,MFAP3L,DRP2,DTNA,EDN3,CORO2B,FGFR1,DCTN2,PRELID3A,FYB1,GABRA3,SIGLEC8,LYVE1,HSF2,KCNQ3,PCSK5,PDE4B,MAPK10,RFX2,KANSL3,CXXC4,UNC5B,SYT5,ADGRL3,OBSL1,SLC44A1,TPM1,NPL,VIPR2,NLRP3" Drug 2901_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA1,APAF1,APBB2,CDC14B,PLA2G4C,ATP6V0A1,BMP7,CACNA1G,HIP1R,MAGI1,CLGN,TAOK2,CABP1,RNF14,KLHL3,CELSR3,KAT8,FER,OLFM1,AFF2,NBEA,PRELID3A,ATXN2L,ICA1,MSR1,SAMD14,ZNF862,RFX2,MAP6D1,EMID1,RPS20,KIF16B,ZC3H13,CDK19,ATP10B,TROVE2,EXOC7,TBCEL,IQCE,CHST5,LMF1,ZFP37" Drug 3343_UP Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ALCAM,ALK,APLP1,DNAH17,N4BP2L1,CFAP410,RAB28,CLTB,WHRN,CSF1R,CNTNAP2,SPOCK2,EDNRA,MBNL2,FAM198B,ZNF589,FGF13,FHL1,FLNC,DLL3,FYB1,DISC1,ADAMTS13,TJAP1,IL6ST,KCNN1,KCNQ3,NF1,PDE4D,PGAM2,PPARA,ZMAT4,RPS20,RASA3,SH3BP2,ASAP3,SMARCD3,SNCA,TSNAXIP1,HECW1,TRPM2,PARP11" Drug 5955_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,ALK,AMH,AMPD3,FAM131A,CDC14B,PLA2G4C,DNAH17,CA12,CLGN,TPP1,VAX2,AATK,MFAP3L,ING4,DLC1,PRUNE2,GRM2,ELOVL5,ICA1,KCNN1,MMP16,MX1,NNAT,CNOT4,PALM,PCDH9,SLC25A23,PPP2R2B,KCTD17,RPS6KA2,SLC11A1,SLC14A1,DOP1A,SPTB,SYN2,KIAA1107,DICER1,THRA,NT5M,DNALI1,KCNAB1" Drug 890_DN 5149715; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "LTBP4,BIN1,SYNJ2,CA4,KYAT1,SCARB1,STOML1,QKI,CRY2,USP6NL,PARD6A,MRNIP,FHL1,EFCAB2,FAM49B,CGREF1,INPP5K,MALT1,HTATSF1,FERMT2,INPP5B,MAP4,MAPT,NEK1,NF1,SETD4,STRN3,PRKAB2,PRPH,SAMD9,MAPKBP1,ZHX3,ZBTB43,SYT1,TACC1,TRIM2,ZNF34,TIAM1,CDK20,VAV1,MAP3K12,EPM2A" Drug 4293_DN Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG3,ADRA1D,GAS7,CDK10,SYNJ1,BAIAP3,CACNA1A,CBFA2T2,RCBTB2,HOMER3,CPS1,DTNA,EGFR,ING4,RGS17,COQ7,FGF1,DISC1,SRCAP,POLL,CACFD1,SOX21,GIT1,NF1,NFYA,NTRK2,PDPK1,MAPK7,BEND5,GSTCD,SBF1,ELMO2,BTBD7,SNCA,LHPP,RPGRIP1L,CRTC1,RPRM,VIPR2,XRCC4,PHTF2,SENP7" Drug 4968_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA2A,AP2A2,APOC1,NCOA1,ATP6V0A1,CFAP410,TPP1,AKAP7,CNTNAP2,DCAF8,ACOT8,DTNA,HIPK3,OGA,SYT17,MALT1,RAB30,POLL,GNG4,GRB10,CACFD1,ELOVL5,IPO5,MATK,KITLG,MSI1,ADAM22,NPR2,PLCD1,MBOAT7,ZDHHC14,RNASEL,SH3BP2,PREX2,PEX26,SLC6A8,RBM34,LHPP,SS18,ARHGEF9,EXOC7,PHTF2" Drug 4773_DN Spectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ARRB2,CDK13,STX16,CFLAR,MTMR2,CA12,SLC25A14,CREM,NCOR1,PDE4DIP,DAPK3,NR1D2,GPHN,CDKL3,POLR1B,FGFR1,PDLIM5,INPP5K,TXNL4A,MSL3,MUM1,IL6ST,KIF2A,MBNL1,NFYA,PIK3R1,STRN3,SLC25A36,ZFP30,ZNF430,ZKSCAN3,POGZ,SS18,KANK1,SYNE2,ANKRD12,TMPO,KAT6B,TRIO,LMF1,SH3GLB2,FXR1" Drug 7319_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABHD6,BIN1,APLP1,APOC1,PPFIA3,BID,ARHGEF7,NFS1,SCARB1,CHN2,CSNK1E,USP6NL,ARHGAP24,KLHL3,FEM1B,EGFR,ERCC2,VPS26C,TMEM8B,GCNT2,GPD2,CNTRL,HNMT,KIF2A,NF1,FSD1,PPP5C,ELOVL2,RAD51D,RPS6KA2,ATXN2,OGDHL,CDK5RAP2,ZBTB43,ARHGEF9,VPS13A,R3HDM1,SSBP2,ZKSCAN5,ZBTB14,TFIP11,HPS4" Drug 5983_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "GAS7,PTCH2,SCAPER,RUNX1T1,CBFA2T2,CRY2,CRYM,VCAN,PDE4DIP,DBN1,RUSC2,DUSP9,EDNRA,C3orf18,COQ7,EZH1,DLC1,EFCAB2,TMEM8B,SEPT9,LILRA2,GRIK5,INPP5B,KCNJ5,KITLG,NELL2,NNAT,PCSK1,PFKFB2,MTRF1L,LRP12,TRIM68,RGS4,PNMA8A,SUPT20H,RASA3,SH3GL3,ATP10B,PLCB1,EXOC7,ZEB1,ITM2C" Drug 6806_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AMPH,BIN1,APBA2,CDK13,MARK4,CHRD,ALDH7A1,AZGP1,CACNA1I,KALRN,MTMR7,COL9A3,AATK,CSF1,PDE4DIP,RUSC2,TMCC2,FHL1,GAD1,PCLO,GUCY1A1,HAS2,ICA1,IRF8,MAN2A2,ADAM22,TAGLN3,ZNF862,NF1,SAMD9,PTCH1,RIPOR1,BEND5,CRTAC1,ZMAT4,PKNOX2,SLC11A1,KDM4B,ARHGAP26,DOCK9,TNS2,LAT2" Drug 1818_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "MTUS1,ARNTL,RCBTB2,QKI,SMARCAL1,DAPK3,RUSC2,TOM1,EDN1,IRAK4,ACSL4,SCARA3,SRCAP,HTATSF1,GUCY1A1,DHX35,IFI16,SHISAL1,IL6ST,GIT1,MX1,ZNF862,NACA,NPR2,GPSM2,MBOAT7,POLG,SNRK,RBBP6,DPF2,MRPS18A,FUZ,ST5,IQCE,EIF4ENIF1,CLIP2,XRCC4,MAP3K12,HPS4,NAV3,UBE3B,SMIM8" Drug 5829_UP Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA1,MTUS1,C1QTNF1,BIN1,AMT,CDC14B,CFLAR,MYRF,LHX2,COL9A3,HAPLN1,CNTNAP2,GIT2,DBT,DPH1,MRNIP,ELN,ETV1,BAIAP2,CHL1,GCNT2,AHDC1,TDRKH,GSTM5,MAP4K5,ENPP2,PPP5C,SH3TC2,FAT4,FAM184A,RET,CLIP1,ZNF821,AMBRA1,PEX26,ZBTB43,TAL1,CRTC1,PCDHA5,FLRT2,WIPF1,LAT2" Drug 2154_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADD2,AGT,FAM135A,CDC42BPA,SEMA4G,AZGP1,CACNA1I,CREM,CSF1,VCAN,SPOCK2,SV2B,CNNM1,EGR3,CALCRL,EIF1,GFER,ZNF276,GUCY1A1,ICA1,MAP4,AFF1,LYRM9,ZNF862,NNAT,ENPP2,MTRF1L,FSD1,PRKAR1B,PTPN13,PTPRB,RIPOR1,ZCWPW1,GAL3ST4,PLPPR3,SLC9A5,PHLDB1,SYN2,ADGRL3,CRTC1,SLC35G2,RUNDC3B" Drug 2294_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA2A,BIN1,GAS7,APLP1,PTCH2,CALB2,ARHGAP33,LHX2,ARHGEF6,PICK1,RASSF2,SPOCK3,CORO2B,TPK1,GPR75,GNAO1,SOX21,ITGA7,IPO5,MID1,NNAT,NTRK2,CLDN11,PDE4B,PLTP,SAMD9,PTCH1,KHDRBS2,GAL3ST4,KCTD17,NUDT11,SLC6A8,CXXC4,UNC5B,ZC3H13,SPTB,ZBTB43,JMJD6,CRTC1,GPR161,TNS1,VIPR2" Drug 4789_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NME5,ALCAM,CDC42BPA,KCNAB2,APOC1,CDK13,ATP6V0A1,CACNA1I,LDLRAD4,CALB2,CDO1,RAB28,TPP1,NECTIN3,CPS1,CRMP1,SNX29,MBNL2,CALCRL,PTK2B,DLC1,FGF13,GCNT2,LPAR4,GPER1,KCNQ3,MYT1,PALM,PCDH9,GRAMD1C,NKAIN1,EMID1,ZNF821,PREX2,CXXC4,SNCA,ZC3H13,ARHGAP26,TBL1X,CRTC1,KCNAB1,ST7" Drug 1002_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,NDRG2,AK2,CDK13,ATP2A2,CAMK2G,TAOK2,SLC4A8,ARHGEF10,PDE4DIP,DAPK3,ARMCX2,HIPK3,VPS26C,ZNF589,CAMKK2,GAD1,B4GALNT1,DISC1,GLYR1,HSF2,LSS,MATK,LYRM9,ZNF862,NF1,OGG1,SLC25A23,FAM184A,RGS3,ANKRD6,KANSL3,LIMCH1,KDM4C,ZBTB43,THSD1,DIP2A,VPS13A,PLCB1,UPF3A,GDPD5,PHTF2" Drug 6721_UP Nitrofural [59-87-0]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ALK,AMPH,APC,GAS7,DDO,CDC14B,ARHGDIG,LDLRAD4,CALB2,CRMP1,SUSD5,PDE4DIP,PHF14,C2CD2L,SEMA3D,PLXNC1,F5,DLC1,FGF1,PRELID3A,TRAF3IP2,ERAP1,GRIK5,INPP5B,TAGLN3,NPTX2,RETREG1,PPP5C,GDPD2,PTN,PTPRB,FBXO11,DZIP1,ANKRD6,PKNOX2,SLC9A5,SNAP25,DOK5,ZC3H13,TIMP4,KCNAB1,NLRP3" Drug 7514_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABHD6,BIN1,APC,BCAS1,CDK10,SEMA4G,ARNTL,ST3GAL5,MTMR2,KYAT1,PREPL,DZIP3,DBT,RUSC2,EGFR,RGS17,STX2,ERCC2,GPER1,GRB10,ACOT7,ITPKB,JAK2,NF1,CCSER2,RETREG1,PLCD1,SLC25A23,VPS13C,RGS12,ZFP30,FNBP1,KDM4C,SS18,NSFL1C,MTCL1,SIK3,TK2,TRIO,CLDND1,XRCC4,ZBTB14" Drug 5948_UP rotenone; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NME5,LGR5,ATP2B2,KIF1A,SYNJ2,SCAPER,MYRF,HAP1,USP2,SCARB1,ARMC8,HAPLN1,DZIP3,GIT2,DMPK,TNK2,OGA,ERAP1,GLI2,POLL,PADI2,TJAP1,MAPT,MITF,NPR2,PCBP3,PFKFB3,GRAMD1C,FRMPD1,ZNF667,RBM34,ARHGAP26,SPTB,EXOC7,SMG6,SZT2,TK2,TRIO,HPS4,SEMA3B,EPM2A,TIGD6" Drug 4425_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,ADRA1D,SEMA6A,TRMT9B,BIN1,APAF1,SEMA4G,MARK4,HAP1,CAMK2B,STOML1,WHRN,CSF1,HDAC9,EDN1,F5,DLC1,FGFR1,SCARA3,AGAP2,TMEM8B,SIGLEC8,NEU3,GPR162,LYVE1,GPER1,KCNN2,KIFC3,MAPT,ADAM22,NF1,PLCB2,RFX2,LIMCH1,HECW1,PEG10,ARHGAP26,TMEM121,TNS1,PIK3R5,TRPM2,ITM2C" Drug 3723_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASPHD1,NDRG2,EPB41L5,GAS7,NRP2,BMP7,SYNJ1,CFAP410,CAMK2B,RUNX1T1,SYNGR3,TPP1,DTNA,CELSR3,EGFR,OLFM1,HPCAL4,FYB1,B4GALNT1,GNAO1,KCNH2,LSS,NF1,NNAT,PALM,MTRF1L,PRKAR1B,PTN,RGS3,RGS4,RGS12,RNASEL,GSTCD,EMID1,RASA3,SPTAN1,SYN2,SYT5,TLR4,RPRM,LAT2,XRCC4" Drug 2479_DN Tiabendazole [148-79-8]; Down 200; 19.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,NDRG3,NDRG2,BRAP,MTUS1,GAS7,NCOA1,CACNA1A,HIP1R,CD86,RAB28,CLCN3,CREM,SH2B1,CNNM1,CELSR3,PIPOX,PDLIM5,CELF1,INPP5K,SRCAP,PADI2,JAK2,SCAMP5,NF1,OGG1,PTK2,PTPRN2,RAD51D,SBF1,IZUMO4,JMJD6,ADGRL3,ZEB1,ICAM5,TLR4,TRPS1,LMF1,XRCC4,ZNF74,EMSY,TIGD6" Drug 3550_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,AMT,ADGRB1,GYG2,CFAP410,CHRNA4,HOMER3,CPS1,PDE4DIP,CNTNAP2,FAM169A,SEMA3D,AASS,RASGRP2,SPEG,DLC1,ZNF44,ERAP1,SIGLEC8,GNAO1,GPD2,GRM8,INPP5B,P2RY1,ENPP2,NLE1,SAMD9,PTN,CCDC40,RPS6KA2,EMID1,ASAP3,CNKSR2,PKNOX2,SNCA,TSNAXIP1,SYN2,WSCD1,SZT2,ICAM5,OSBP2,AP3B2" Drug 3802_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "APAF1,ARRB1,ATP6V0A1,ADGRB2,CACNA1I,MYRF,CFAP410,CD86,TAOK2,TPP1,VAX2,NCOR2,DTNA,DTNB,ETV1,SEMA4D,DISC1,RUNDC3A,GLYR1,GRM8,KCNJ5,KCNN1,KCNN2,KITLG,AFDN,NF1,NPTX2,TREM2,PDE4D,GPR85,PURG,C19orf57,FSD1,LRRN3,RGS12,SNAP25,LMO3,NXT2,TPM1,TUBB1,LAT2,SPHK2" Drug 4019_UP Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASPHD1,ALK,AMH,BIN1,SEMA7A,ARSE,SLC4A4,ADAM23,BMP7,CAMK2B,LDB2,SCARB1,AKAP7,IQCK,AKAP5,CSF1R,CNTNAP2,TOM1,SEMA3D,PLXNC1,ZNF391,DLC1,SIGLEC8,GPD1,GPER1,GRIK5,MAN2A2,MIA2,MMP16,SLC11A2,PALM,PLCD1,GAL3ST4,DZIP1,PPP4R3A,ELMO2,PHLDB1,KLHL4,CRTC1,CDK20,ZNF24,PHTF2" Drug 3237_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "APC,PTCH2,ADGRB2,CA4,CBFA2T2,RAB33A,TPP1,FAM189A2,SULT4A1,BAG4,VCAN,RIMS2,CYBB,SNPH,RASSF2,EDNRA,EDNRB,AFF2,PRELID3A,ITGA7,KCNJ5,KCNN1,KIT,IPO5,MEIS1,CLDN11,PALM,PLCD1,MAPK7,GRAMD1C,RIPOR1,KCTD17,SH3BP2,SYBU,SLC2A5,DHX30,SLC22A4,ARHGAP26,EXOC7,RIMBP2,R3HDM1,XRCC4" Drug 2140_DN Seneciphylline [480-81-9]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "CDC42BPA,APC,FOXN3,RAB33A,CLTB,CREM,DGKG,C2CD2L,SGSM2,EXOG,ELN,RASGRP2,NCALD,VPS26C,ANKMY1,KAT8,KHDRBS3,ZNF44,ERAP1,GNG4,GPD2,LILRA2,DIDO1,FICD,GIT1,MYT1,NF1,PLTP,PMP22,TMEM231,RET,ZNF821,PEX26,SLC11A1,ZKSCAN3,SP4,SS18,PLCB1,TCF4,ZEB1,UBTF,LMF1" Drug 3174_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AMPD3,CDC14B,ARHGDIG,ATP2B2,B4GALT6,SLIT2,CSF1,HDAC4,DPP6,CALCRL,ETV1,F5,FHL1,CHL1,PCDH17,GPD2,TDRKH,GRM8,GSN,MEF2C,AFF1,AFDN,MSR1,NCF2,PCBP3,RETREG1,PLTP,MAPK7,MAPK10,RGS12,KCTD17,PREX2,SLC9A5,SNAP25,SP4,CDK19,ATP10B,PHLDB1,WIPF1,ZNF45,NT5M,NLRP3" Drug 2372_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADORA1,FAM135A,CDK10,NCOA1,CA12,CBFA2T2,CDH2,SOCS6,HOMER3,CREM,DCAF4,INTS1,GSDME,MBNL2,PIPOX,PDLIM5,GLI2,GNG4,KIT,MBP,MEF2C,LYRM9,SLC11A2,PLCD1,SLC25A23,MASP1,KLK6,PTPRB,RGS3,ZNF821,ASAP3,KDM4B,DOP1A,SPART,TROVE2,TBCEL,OBSL1,CRTC1,TUBB1,PLPPR2,ZBTB38,EVI5" Drug 4175_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "GAS7,SEMA4G,MARK4,ALDH7A1,LDLRAD4,CFAP410,PTBP2,SLC16A4,WHRN,SPOCK2,TMCC2,EXOG,IRAK4,ELN,EZH1,FHL1,AFF2,DISC1,SEPT9,GNG4,ICA1,TJAP1,KCNN1,MAPT,ADAM22,MX1,MYT1,PDE1C,PRKAR1B,WDR25,C1orf54,SH3GL3,SNAP25,CLSTN2,THSD1,VPS13A,PLCB1,ARC,MCF2L,TBCEL,TPM2,EPM2A" Drug 2_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADD2,APAF1,APC,PDE8B,AZGP1,KSR1,BMP7,CBFA2T2,AKAP7,BRINP1,TSPAN5,ING4,MRNIP,CALCRL,EPHB1,ZNF589,FHL1,FLNC,FAM49B,NSG1,SRCAP,FAM107A,PADI2,ICA1,IL6ST,MGAT3,NEK1,NF1,NTRK3,PLCD1,POLG,PRODH,MTMR10,RIPOR1,GAL3ST4,TCP11L1,AMBRA1,FNDC3A,LMO3,PRRC2C,EXOC7,TNS1" Drug 2360_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "DOC2A,SEMA4G,N4BP2L1,KSR1,BMP7,CALB2,CD86,CD38,TAOK2,CPS1,CREM,PDE4DIP,PPP1R16B,ARHGEF4,SNPH,ZNF337,MBNL2,MRNIP,COQ7,MTSS1L,FHL1,PDLIM5,PRELID3A,SIGLEC8,INPP5K,SPACA9,KCNJ5,MEF2C,GIT1,NF1,PDE4B,PPP2R2B,PTPRE,RFX2,RGS3,KCTD17,SH3BP2,SPTAN1,RBM26,SS18,TK2,FAM13C" Drug 4395_UP Cyanocobalamin [68-19-9]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG2,ADRA1B,ADGRF5,APBA2,CDC14B,ARHGDIG,GYG2,BAIAP3,CAMK2B,TAOK2,CRYM,CSF1,VCAN,PDE4DIP,KIAA0319,DMPK,EIF4G2,TNK2,PIPOX,PTK2B,DLC1,SCARA3,FYN,RUNDC3A,ADAMTS13,GSTM5,KCNB1,NCF2,NOVA1,OPRL1,CDK18,SAMD9,RGS3,ARHGEF40,TACR1,DICER1,TNS1,FAM155A,OSBP2,LAMP5,SLC30A3,ITM2C" Drug 7203_UP Vidarabine [5536-17-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "NDRG2,BEGAIN,DOC2A,TRMT9B,ARRB1,MARK4,ATP1A3,AZGP1,SYNJ1,ST3GAL5,CA4,CACNB4,ARHGEF2,CHRNA4,CSF1R,CYBB,PARD6A,FGFR1,SEPT9,SRCAP,STON1,GRM8,HNMT,LIG4,ADAM22,ZNF862,CNOT4,SLC11A2,P2RY1,STRN3,PRPH,SAMD9,RGS12,MRAS,ASAP3,SYBU,IZUMO4,CHST8,TLR4,TFIP11,NT5M,JPH3" Drug 5875_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,SYN3,ADRA1D,AGT,APAF1,APC,ARRB2,PDE8B,RGS11,NRP2,SYNJ1,BAIAP3,CACNA1A,KALRN,LY86,RAB26,SPOCK2,AASS,OGA,GFER,USP19,PCDH17,GPD2,PLCD1,SMOX,PPP1R1A,PRKAR1B,ASAP3,FAM214B,IFT122,HECW1,ARHGAP26,DDN,CAMTA2,PLCB1,SYT1,TMEM121,TK2,VAV1,ADAMTS9,HPS4,KCNAB1" Drug 5482_DN Diprophylline [479-18-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "CDC42BPA,SCAPER,SPAG9,CRLF1,SOCS5,PDE4DIP,FEM1B,IRAK4,BAIAP2,POLL,MAP4,MIA2,MPP2,ZNF862,NF1,NFYA,PDE4A,PDE4B,CCSER2,SMIM7,PRODH,RNH1,GSTCD,SAFB,ZNF821,CDK5RAP2,MAPKBP1,KDM4C,CDK19,ELOVL4,STX1A,IQCE,ZNF34,TIAM1,CABIN1,RPRM,UBTF,PLPPR2,KLC2,ZNF74,ZFAND5,HPS4" Drug 5427_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "BIN1,GAS7,APOC1,CDC14B,CDK13,USP2,CBFA2T2,SOCS6,SULT4A1,PCYT1B,ARHGEF4,CYBB,ECM2,EDNRA,MBNL2,ERCC2,BAIAP2,PCLO,NXPH3,HLF,LIFR,MAP4,GIT1,ADAM22,MBOAT7,PPP2R2B,CEP41,PRKAR1B,PTN,ZCWPW1,FNDC3A,FAM214B,SLC9A5,ZHX3,HECW1,SPTAN1,CDK19,ARC,SYT5,ZEB1,ZNF34,DPF3" Drug 7481_UP (-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AMPH,BIN1,KCNAB2,APC,SEMA4G,SLC4A4,KIF1A,BMP7,SYNJ2,CBFA2T2,SOCS6,RAB33A,PLAA,NCOR2,JAKMIP2,CELSR3,MRNIP,FECH,USP19,RAB30,GPR37,AP4S1,TJAP1,INPP5B,ITPKB,KCNN1,MATK,PLXNB1,MBOAT7,RIPOR1,RGS4,ZFHX4,ELOVL4,STX1A,CRTC1,ZNF34,TIAM1,TK2,PARD3,VIPR2,KCNK12,SEMA3B" Drug 7522_DN CP-645525-01 [287190-82-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ABHD6,ADORA1,ADORA2A,AK2,APBA2,MARK4,GYG2,FOXN3,WHRN,EXOG,DTNA,SNX29,VPS26C,FGFR1,PRKAG2,FOXF2,FAM49B,POLL,GNG4,AFF1,ADAM22,NNAT,PALM,PCDH9,DUSP26,NLE1,PLTP,LRP12,CCDC40,NEK11,EMID1,FERMT1,SLC6A8,TTBK2,TBL1X,TRIO,KCNK12,EMSY,GDPD5,HPS4,ITM2C,ACTR3B" Drug 4486_UP Napelline [5008-52-6]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,SEMA7A,APAF1,PRX,PPP4R4,CDK13,NRP2,CACNA1I,CAMK2B,CHN2,STOML1,RCHY1,CSF1,RIMS2,DMPK,IGSF6,APC2,ETV1,DLC1,PDLIM5,RUNDC3A,GNG4,TDRKH,GRIK5,ATXN2L,ICA1,TJAP1,SCIN,ITGA7,CNOT4,NOVA2,NLE1,PRKAR1B,ZSCAN32,RPS20,SUPT20H,SLC6A11,SYT5,SMG6,CUX2,REEP1,SEMA3B" Drug 6088_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "RALGAPA1,ADCY6,ALK,BIN1,N4BP2L1,CACNA1I,CDO1,SULT4A1,CPS1,ARHGEF10,RASSF2,EDNRB,IGSF6,F5,FYN,NEU3,SRCAP,RUNDC3A,GNAO1,PRUNE2,ADAMTS13,ATXN2L,C2orf72,KHK,MGAT3,KITLG,AFDN,NOVA1,NTRK3,PCDHGC3,CDK18,PDE1C,LRP12,GDPD2,RFX2,RGS12,KCTD17,SLC11A1,ZC3H13,CLSTN2,CUX2,DNAH7" Drug 481_DN WY-14643; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADD2,MTUS1,KCNAB2,ARRB2,BMPR1B,CA12,CACNA2D1,KCNAB3,SRSF11,NDST3,LHX2,CLTB,ABI3BP,CRMP1,PDE4DIP,GIT2,EGFR,CORO2B,ST3GAL6,FCGRT,FOLR2,CAMKK2,NSG1,MAN2A2,MAPT,MGAT3,MT1M,NACA,PLXNB1,C19orf57,PRKAR1B,MARCH1,CSRNP3,FNBP1,SPTB,PLCB1,EXOC7,DOCK9,CRTC1,VIPR2,SPHK2,MAP3K12" Drug 3801_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASPHD1,ALK,SEMA7A,NRP2,ARHGAP33,CACNA2D2,FOXN3,TPP1,ARMC8,CNTNAP2,RIMS2,ECM2,SUGP2,MRNIP,FGF1,FGFR1,SRCAP,GRIK5,ATXN2L,ICA1,TJAP1,ITGA7,LAMA2,MAP2,MAPT,PIK3R1,ZCWPW1,ZNF671,RASA3,ST6GAL1,NLGN1,SLC4A3,TSNAXIP1,IQSEC2,THSD1,KIAA1107,TBCEL,RPGRIP1L,TNS1,TRIO,XRCC4,REEP1" Drug 6369_UP CGX 0596987; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "DOC2A,BIN1,PKP4,GAS7,ADGRB2,NRP2,BMP7,CBFA2T2,AKAP5,CSF1,ZNF804A,MFAP3L,C2CD2L,KIAA0319,DTNA,DTNB,EDNRA,EFCAB2,CSPG5,FYB1,DENND2A,ADAM28,GNAL,KCND1,KIF2A,ADAM22,ZNF862,NCAM2,LRRN3,CEP41,PTCH1,PTPRB,PTPRH,BEND5,RNASE1,KDM4B,SPTAN1,SYT1,DOCK9,TPM2,VGF,VLDLR" Drug 2424_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "FGD2,KIF1A,ADGRB1,KSR1,ARHGEF7,CACNA1G,CFAP410,LARGE1,CACNA2D2,CHN2,CREM,ABCG1,PDE4DIP,DZIP3,DTNB,SRPK3,EPHB1,DLC1,FGFR1,PRELID3A,GLI2,GLYR1,TDRKH,KCNJ5,MPP2,MYCN,MYO6,MYT1,NEFM,NTRK2,OPRL1,FA2H,PTPN13,ZFHX4,SEMA6D,SH3BGR,KDM4B,ATP10B,ZFPM2,AP4E1,ZNF711,DPF3" Drug 2128_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ALK,BEGAIN,SEMA4G,SCAPER,TAOK2,CRMP1,ABCG1,CSF1R,DCAF4,DAPK3,MED12,FCF1,SUGP2,C3orf18,FAM49B,B4GALNT1,DISC1,TDRKH,MAP4K5,TJAP1,IPO5,MAPT,MEF2C,MMP16,GIT1,ZNF862,PCBP3,PRPH,SH3TC2,RGS4,MAPK12,ATXN7,DZIP1,ZKSCAN3,SPTAN1,COBL,TBL1X,SYNE1,CABIN1,HIRA,UCHL1,EVI5" Drug 6080_DN Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ADCY6,NME5,AK2,APC,ARRB1,ADAM23,CFLAR,MTMR3,ARHGEF1,CBFA2T2,FAM189A2,AKAP7,CSF1R,MAML1,ZNF804A,RUSC2,C2CD2L,OPTN,NCALD,ZNF589,FGFR1,SYT17,SRCAP,GNG4,RNFT2,INPP5B,KPNA5,MSI1,ADAM22,PDE4B,RETREG1,MAPK7,TMEM231,RAD51D,SEMA6D,PEX26,KIF13A,KDM4C,PHLDB1,PLCB1,TACC1,TRIM2" Drug 4609_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AK2,ALK,CDC42BPA,GAS7,N4BP2L1,KSR1,CFAP410,CACNB4,TPP1,PDE4DIP,MYEF2,DRP2,CNNM1,PLXNC1,FYB1,GABRA3,GRM8,KCNJ5,PACRG,MBNL1,MYH3,MYO7A,PCSK5,PDE4B,PDE4D,PIK3R1,STRN3,NEK11,MRAS,RASA3,ARHGEF40,SNCA,ARC,SYT5,TACR1,DOCK9,TNS1,TRIO,UBE3A,WIPF1,SLC17A7,EPM2A" Drug 6347_UP Isradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AGT,DOC2A,BIN1,EPB41L5,PPP4R4,CFLAR,BAIAP3,RUNX1T1,LY86,AKAP7,PDE4DIP,EGFR,FGF1,FOXF2,TRMO,OGA,SEPT9,NEU3,GLYR1,KCNF1,LIG4,ENPP2,DUSP26,CCSER2,POU6F1,PPARA,RASGRF1,GAL3ST4,RGS4,TCP11L1,SALL1,ZNF821,KANSL3,BTBD7,SMARCD3,KDM4C,SPTB,IQSEC2,AP4E1,TNS1,HIRA,DPF3" Drug 6043_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "ASIC1,ABHD6,ADRA1D,PPFIA3,ARRB1,SYNJ2,USP2,ARHGEF2,SEPT7,FOXN3,QKI,HOMER3,NECTIN3,HINFP,CSF1,FAM169A,RASSF2,RCAN1,KAT8,FGFR1,ANKFY1,OGA,TRAF3IP2,GNG4,TDRKH,KCNF1,MAP4,ZNF862,NF1,ZFHX4,TRAPPC13,SUPT20H,ANKRD6,SLC6A8,ZHX3,KDM4C,PHLDB1,KIAA0930,TRIM2,PCDHA5,VGF,MPPE1" Drug 5055_DN Norethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "APBB2,APOC1,PPFIA3,CDC14B,MARK4,SLC4A4,HIP1R,EPS15L1,RAB28,HAPLN1,CSF1R,GPRASP1,DTNA,HIPK3,MBNL2,STX2,ERBB2,CAMKK2,SESN1,RNFT2,BACH2,HSF2,KPNA5,MAPT,ZNF862,CNOT4,SNX10,FA2H,MAPK7,SCN8A,DZIP1,WDR37,LIMS2,SPTAN1,ELOVL4,ASTN2,TRIO,UGT8,VIPR2,NDRG4,SPHK2,HPS4" Drug 4196_UP Benperidol [2062-84-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.53E-05 1.00E+00 7.86E-04 8.85E-03 42 198 "AP2A2,NRP2,HAP1,CAMK2A,LDB2,ARHGEF2,SEPT7,MAGI1,AKAP5,ABCG1,RGS6,SUSD5,DBT,ING4,DISC1,GSTM5,ADAM11,P2RY13,NF1,SMOX,PTN,PTPRG,ACSS3,C1orf54,GAL3ST4,RFX2,RPS20,KCNIP1,DZIP1,PREX2,PKNOX2,OGDHL,DOP1A,ZHX3,THSD1,FBXW11,TK2,RPRM,ZNF154,SLC17A7,KCNAB1,EPM2A" Drug ctd:D003976 Diazinon CTD 4.63E-05 1.00E+00 8.02E-04 9.04E-03 222 1525 "ACHE,ABHD6,ACTN1,NDRG2,ADCY8,FZD9,UNC5A,ADRB2,AP2A2,TBC1D14,ZNF687,BIN1,SEMA7A,APAF1,PPFIA3,AQP6,MADD,SPTBN4,ARRB1,CDK13,CHRD,ATP1A1,AZGP1,BCHE,BCL7A,CFLAR,AP1M1,CACNA1G,BAIAP3,DDR1,CALM1,CAMK2G,HIP1R,CCNH,CD86,SCARB1,AP4M1,CCPG1,COPB2,CHGB,CHRNA4,LY86,ARHGEF6,PICK1,ABCG1,PHACTR3,GPSM1,DOCK4,KCTD8,DAPK3,BRINP1,DBN1,ELMSAN1,MYEF2,C2CD2L,PARD6A,TMCC2,SLC29A4,SHANK1,CPEB2,CASP8AP2,FIS1,EDN3,HEYL,EGFR,RGS17,PAN3,SRRM1,RASL12,PTK2B,RACK1,FECH,FGF1,FGF12,FGF14,FGFR1,FGFR3,PRKAG2,MEX3B,FOXO3,WDR83,CINP,APOPT1,ERGIC3,CGREF1,FYN,IQGAP2,CPLX2,GCNT2,ARFIP1,NTNG2,GLYR1,AIFM3,GNAO1,FERMT2,GPT2,GRIA2,DIDO1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GSTM5,GSTT2,ZHX1,NXPH3,PACSIN2,MAN1B1,IDH3B,IGF1,KNDC1,IL12A,INPP5B,ITPKA,GATD1,KIT,CAMK2N2,SFXN5,LSS,TM6SF1,MN1,MPP2,GIT1,ADAM22,SAMD14,MYCN,MYO9A,NBL1,NEFM,NEFH,NFYA,NNAT,NPY,NPR2,NTRK2,NTRK3,PAX6,PCSK5,PDCD2,PDE1C,PDE3A,ABCB1,PKD1,TMEM38A,KCTD15,PMP22,PILRA,POLG,SH3KBP1,POLR2F,PPARA,PPP5C,PRKAB2,MAPK3,CNNM2,PSD,QRICH1,PTCH1,PTN,PID1,DPF2,RET,REV3L,RFX3,RGS3,MRAP2,EPHA10,HSD11B1L,S100B,MAPK12,HES6,SMPD3,CNKSR2,SLC6A8,SIRT2,SLC12A4,RBM34,KDM4B,KDM3A,SP4,PEG10,CAMTA2,CEP68,STX1A,JMJD6,PLCB1,TAF6,MCF2L,CUX2,ZMAT3,AKTIP,THRA,NACC2,ICAM5,TLR4,FAM124A,TP53BP2,CDK20,NR2C2,UCHL1,BCL2L13,MGAT5B,MTCH1,PLPPR2,VLDLR,CLIP2,KLC2,CFAP298,ZNF540,TFIP11,EMSY,SLC38A1,PRDM10,SEMA3B,SIGLEC10,PCBP4,PLD4,FZD3,RTN4,AP3B2" Drug 7285_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.63E-05 1.00E+00 8.02E-04 9.04E-03 38 173 "ADRB2,MTUS1,SHROOM2,ARNTL,ST3GAL5,NRXN3,CLTB,PREPL,ABCG1,PDE4DIP,CTH,JAKMIP2,PLPPR4,EPB41L2,TAOK3,BAIAP2,FYN,GUCY1B1,FAM69A,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,ENOX1,RGS4,SH3GL3,DOP1A,ARHGAP26,THSD1,RGL1,SYT1,KIAA0930,RUNDC3B,SSBP2,TRIM9,KCNAB1,PLSCR4" Drug 6207_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "CDC42BPA,MARCH3,CFLAR,MTMR2,CNOT8,NCOR1,ABCG1,CSNK1E,PPP6R2,DCAF8,GIT2,LYPD1,MAMLD1,MRNIP,EPB41L2,FGFR3,CAMKK2,ZNF276,BTN2A1,RBPJ,JAK2,KIF2A,MAPT,MIA2,NFYA,RIPOR1,RGS3,MAPK12,SUPT20H,FBXO11,SIRT2,TMCC1,ITPRID2,CBX5,TMPO,KAT6B,UBTF,VAV1,ZBTB38,EVI5,FZD3" Drug 4613_UP Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "CDK10,ARHGEF2,CBARP,FAM149A,AKAP6,CRY2,RGS6,MFAP3L,DRP2,DTNA,PLXNC1,EPB41,DCTN2,SIGLEC8,ADAM28,CSDC2,GNG4,GPD1,STMN2,SPACA9,MAN2A2,MMP16,MT1M,NF1,CNOT4,PDE4D,FA2H,PRKAR1B,GSTCD,NEK11,RTN1,RASA3,OGDHL,ARHGAP26,ARC,SYP,OBSL1,DNAH7,ZFPM2,TLR4,NLRP3" Drug 3386_DN Propofol [2078-54-8]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "NME5,AK2,BIN1,APBB2,APC,APLP1,FAM131A,SLC2A11,CFLAR,SCAPER,GREB1,MAML1,ZNF804A,DMPK,DTNA,SUGP2,FGFR1,FAM49B,TRAF3IP2,ALDH1L1,MALT1,ADAM22,CDK18,RETREG1,PMP22,LRP12,RETREG2,MBOAT7,GRAMD1C,ZFHX4,TCP11L1,RASA3,FAM214B,KIF13A,ZNF423,ZBTB43,EXOC7,KIAA1107,TBCEL,DMXL2,PDIA2" Drug 1165_UP trifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "AMT,GAS7,ARNTL,NCOA1,CDO1,SOCS6,RAB28,SULT4A1,AKAP7,IQCK,DZIP3,CTH,HDAC9,KIAA0753,RCAN1,DTNA,PLXNC1,EPB41L2,CGREF1,SRCAP,ZNF276,GLYR1,LPAR4,FICD,HMGCR,LSS,ZNF862,P2RX7,ENPP2,CCSER2,RPS6KA2,RBM34,SPP1,ZBTB43,ARHGEF9,ZMAT3,PLPPR2,NPDC1,ZBTB38,EPM2A,PHTF2" Drug 2183_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "SYN3,ABHD6,BIN1,CDC42BPA,APBB2,ARHGDIG,DNAH17,AZGP1,BMP7,LHX2,TPP1,CNR1,AKAP6,VCAN,RIPOR2,PHC2,FAM13A,MBNL2,EPHB1,FER,FLT1,PDLIM5,NSG1,LILRA2,KCNJ5,MEF2C,AFDN,PDE4A,PFKFB2,PLCD1,SLC25A23,MTRF1L,PMP22,LRRN3,PTPRN2,RGS3,SEMA6D,SPTB,RUNDC3B,FLRT2,KCNAB1" Drug 3858_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "ADRA1D,LTBP4,AMH,APC,FAM131A,BMP7,CFAP410,C2CD2,ARHGEF4,RIMS2,RASGRP1,EGR3,ELN,FGFR1,ALDH1L1,GFER,MSL3,POLL,ATXN2L,NPR2,PFKFB3,PLCD1,PPP5C,MAPK7,PTPRE,ENOX1,ZMAT4,RET,EMID1,SH3BP2,ASAP3,FAM214B,LIMCH1,KIF13A,MCF2L,CHST8,TIAM1,TK2,VIPR2,LAT2,GDPD5" Drug 7536_UP 0393-0188; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "ZBTB10,SCAPER,MYRF,SOCS6,LHX2,PLAA,HOMER3,SLC4A8,CRY2,HINFP,SLITRK5,TMCC2,EDIL3,CELSR3,EIF5,FYB1,B4GALNT1,POLL,SCIN,FAM69A,KCNJ5,KCNN1,CNOT4,CLDN11,PTN,FAT4,KCTD17,RPS6KA2,CLIP1,FAM214B,SMARCD3,ELOVL4,TTBK2,SYT1,TNS1,TRIO,RUNDC3B,HIRA,FAM155A,EPM2A,RNF146" Drug 5238_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.73E-05 1.00E+00 8.17E-04 9.20E-03 41 192 "NME5,APC,ATP2B2,USP2,CBFA2T2,SOCS6,LHX2,WHRN,GIT2,RUSC2,SPOCK3,CDON,RCAN1,MBNL2,EGR3,VPS13B,DLC1,FGFR1,FHL1,TMEM8B,LYVE1,RUNDC3A,JAK2,KPNA5,MAPT,ADAM22,NF1,NTRK2,LRP12,SAMD9,ZMAT4,RET,TCP11L1,SGK1,SH3BP2,SYBU,KDM4B,RGL1,PLCB1,ARC,SEMA3B" Drug 1745_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.77E-05 1.00E+00 8.23E-04 9.27E-03 37 167 "BIN1,FAM131A,DNAH17,RASL11B,CFLAR,CD86,CD38,CHN2,CREM,SIPA1L1,PPP1R16B,DOCK4,ZFYVE16,FAM13A,KAT8,BAIAP2,PRKAG2,MALT1,PTPRT,ADAMTS6,AFF1,PDE4B,PDE4D,PIK3R1,GPSM2,SMOX,CCDC40,SATB1,ATXN2,SGK1,ZC3H13,SPTAN1,SAMSN1,PLCB1,TCF4,SZT2,SLC44A1" Drug CID000000295 "guanosine 3',5'-cyclic monophosphoric acid" Stitch 4.79E-05 1.00E+00 8.26E-04 9.31E-03 97 577 "KCNH8,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,AGT,DOC2A,MYH7B,ARRB1,ARRB2,PDE8B,ATP1A3,ALDH7A1,RGS9,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,PRC1,CCK,KRIT1,CD38,LRBA,CACNA2D2,MYL6B,CNGA3,CRY2,DMD,DNAH9,SLC25A18,ABCC5,E2F6,EDN1,EDN3,EDNRA,EDNRB,PHC2,NCALD,MRVI1,EZH1,SCML2,PPP1R1B,IP6K2,DOT1L,GFER,CRCP,KDM2B,KCNMB4,GRIN2C,GRIN2D,ATE1,GUCY1A1,GUCY1B1,HBA1,TNFAIP8L3,MYLK2,KCNH2,KIFC3,NBL1,NPR2,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PKD1,PKM,PLCB2,POLR2F,PPARA,PRKACB,PRKCB,MAPK3,MAPK9,PRPH,RYR3,MAPK12,GKAP1,SMARCA4,PEG10,SAMSN1,SEPT3,PLCB1,TBL1X,USP22,ACTR6,TMPO,VSNL1" Drug CID000159654 neferine Stitch 4.87E-05 1.00E+00 8.41E-04 9.47E-03 6 8 "DTNB,LRRC25,MAPT,ABCB1,S100B,RGL1" Drug 4707_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.92E-05 1.00E+00 8.47E-04 9.55E-03 40 186 "RALGAPA1,NME5,KCNAB2,APBB2,APC,CDK13,PDE8B,UBE2L6,SOCS6,TPP1,CSF1,FAM169A,PARD6A,DTNA,EIF4G2,NCALD,RRAGB,FGF13,GAD1,SIGLEC8,NEU3,GLYR1,TDRKH,GPER1,GSN,MBNL1,KITLG,MID1,STRN3,C1orf54,CARF,PNMA8A,ZFP2,MRAS,RASA3,ZC3H13,KIAA1107,WSCD1,ZNF24,SEMA3B" Drug 4460_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.92E-05 1.00E+00 8.47E-04 9.55E-03 40 186 "ADD2,TRMT9B,AMT,APAF1,ZBTB10,IL33,RAB33A,AKAP6,PDE4DIP,DZIP3,NR1D2,TENM1,ETV1,REEP2,RUNDC3A,MSL3,STON1,GPR37,SPACA9,ATXN2L,HNMT,IL6ST,KCNH2,MAP2,PDE4B,PDE4D,SERPINI1,PTCH1,PTN,ZCWPW1,RGS3,CARF,SPATA7,CEP68,MCF2L,TCF4,FLRT2,LAT2,ZNF225,PLSCR4" Drug 2130_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.92E-05 1.00E+00 8.47E-04 9.55E-03 40 186 "BIN1,CDC42BPA,APAF1,BMP7,CAMK2B,CD86,SYNGR3,CLGN,CREM,SH2B1,CSNK1E,SIPA1L1,PPP1R16B,DOCK4,DBT,CDON,DTNA,FAM13A,EGR3,EIF1,VPS13B,IQCG,TMEM8B,RUNDC3A,HMGCR,MAP4,NFYA,NNAT,PDE4A,ENPP2,RIPOR1,ZFHX4,MAP6D1,ZC3H13,CEP68,ADGRL3,TBCEL,RUNDC3B,CLDND1,ZFP37" Drug 4327_DN Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.92E-05 1.00E+00 8.47E-04 9.55E-03 40 186 "NME5,APLP1,MARK4,ADGRB2,MYRF,CAMK2G,ARHGEF1,TAOK2,LHX2,PLAA,SMARCAL1,DCAF4,SNPH,RHOBTB1,EIF5,EZH1,TBC1D16,ZNF589,FAM49B,DENND2A,GPER1,ATXN2L,ITPKB,MX1,PDE4A,SAMD9,SH3TC2,MAP6D1,SH3BP2,SLC4A3,LIMS2,SMARCD3,CEP68,PHLDB1,ASTN2,TMEM121,SPHK2,MAP3K12,HPS4,DPF3" Drug CID000061672 orthovanadate Stitch 5.04E-05 1.00E+00 8.55E-04 9.64E-03 77 435 "ADCY5,ADCY6,ADCY8,PDE8B,DNAH17,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,SLC2A11,ALDH7A1,KIF1A,CACNA2D1,CALM1,RGN,ENTPD2,LRBA,ABCG2,DNAL1,DNAH9,DTNB,ABCC5,EGFR,ENPP6,ERBB4,PTK2B,FGF1,ATP6V1H,ATP2C1,GCK,BRD8,MCHR1,IGF1,JAK2,KIF5A,MBP,KITLG,MYO7A,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PFKFB4,ABCB1,PIK3C2A,PIK3R1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK10,PTK2,PTPN13,PTPRB,PTPRD,PTPRG,KIF7,RNASE1,GSTCD,SBF1,KIF27,KIF16B,SLC14A1,KIF13A,SST,SSTR1,SSTR2,PLCB1,ALG1,ACTR6,KLC2,PLD4" Drug CID004369374 AC1N9ZZC Stitch 5.07E-05 1.00E+00 8.55E-04 9.64E-03 34 149 "KCNH8,ADRB2,ANK2,MYH7B,MADD,KIF1A,SYNJ1,AP1M1,C5,CACNA1A,DDR1,SPAG9,CFL2,CLTC,MAP4K4,SNAP91,DPYSL2,GATM,FERMT2,GSN,KIF5A,MYH3,NCAM2,FXYD1,PPP3CA,PTK2,ROBO1,RYR3,SCP2,SLC14A1,UNC5B,ST5,TRIO,NAV3" Drug 5640_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.11E-05 1.00E+00 8.55E-04 9.64E-03 39 180 "CFLAR,PLAA,CLCN3,ARMC8,PDE4DIP,DZIP3,KIAA0586,ZBTB24,RHOBTB1,ANKRD46,EIF5,IRAK4,ARMCX1,SYT17,ITPKB,PDCD2,PIK3R1,NLE1,ZSCAN32,RAD51D,ZCWPW1,RNASEL,ZC3H14,SUPT20H,ZFP30,FERMT1,SYBU,WDR37,SPATA7,ZNF302,CEP68,ZC3H4,ARHGEF9,ASTN2,FAM208A,TRIM2,ZNF23,ZNF74,HPS4" Drug 2715_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1D,AMH,APBB2,PPP4R4,LDLRAD4,EPS15L1,QKI,NRG2,CSF1,SIPA1L1,PPP1R16B,C3orf18,MTSS1L,PIPOX,F5,FGFR1,FHL1,FYB1,GATM,ZNF276,MSL3,TJAP1,IL6ST,MEF2C,AFDN,NNAT,PCDH9,ENPP2,PTN,ZSCAN32,SEC14L1,PREX2,PEX26,SLC11A1,SPTB,LHPP,ADGRL3,SYNE1,TK2,REEP1,SH3GLB2,TIGD6" Drug 6364_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1D,APBB2,CDC14B,CDK13,ADGRB2,MYRF,CFAP410,SCARB1,COL9A1,NRG2,CDON,HEYL,MBNL2,TNK2,VPS13B,F5,DLC1,HPCAL4,TMEM8B,SIGLEC8,CPLX2,SRCAP,ADAMTS13,GRM8,HLF,KCNN1,MAPT,MMP16,NNAT,NOVA2,NTRK2,PTPRN,ZMAT4,SCN2B,SH3BP2,FRMPD1,DOK5,ARHGAP26,PLCB1,DOCK9,TRIO,NT5M" Drug 5093_UP Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASIC1,APAF1,SCAPER,CA8,CHN2,AKAP7,CRY2,PDE4DIP,ARHGEF4,TOM1,TENM1,PTK2B,FGF1,SEMA4D,GAA,GLYR1,GPR75,SPACA9,SYNPO,ICA1,PFKFB3,MAPK7,SNRK,TMEM231,ZCWPW1,NEK11,RPS6KA2,SBF1,ZNF821,BTBD7,COA1,ARHGAP26,DDN,CEP68,SMG6,GPR161,NACC2,RUNDC3B,CLIP2,LAT2,EVI5,EPM2A" Drug 4188_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SEMA6A,ADGRB3,RGS9,PROM1,BMP7,CACNA2D1,CCK,SLC16A4,DLGAP1,CRLF1,ABCG2,FAM149A,DBT,EDN3,ELN,ERBB4,AFF2,NSG1,ERAP1,ADAM28,GLI2,GNAL,ICA1,ADAM22,OPRL1,PDE4B,MTRF1L,PTPRG,RASGRF1,RFX2,RTN1,PKNOX2,BTBD7,SNCA,LMO3,SYP,PCDHGB6,PHF24,THRA,TLR4,EVI5,EPM2A" Drug 4210_UP Diflunisal [22494-42-4]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "APC,CDC14B,ZSCAN18,RGS11,CACNA2D1,CBLN1,USP2,MAGI1,DLGAP1,NRXN3,ABCG2,CNTN1,AKAP5,SPOCK2,DBT,OLFM1,EFCAB2,PDLIM5,LYVE1,GNAL,IL6ST,KCNB1,KCNJ5,KIF5A,MYH3,NF1,PPP2R2B,LRRN3,PRKAR1B,PRKCB,PTCH1,ACSS3,C1orf54,GAL3ST4,KCTD17,SEMA6D,PKNOX2,PLCB1,PHF24,CRTC1,CHST5,SEMA3B" Drug 6452_UP Tyloxapol [25301-02-4]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADGRF5,N4BP2L1,BCHE,SGCE,CACNA1I,CFAP410,CD86,ARHGEF2,WHRN,PDE4DIP,CNTNAP2,SNPH,SPOCK2,MYEF2,DMPK,TNK2,NRN1,FGFR1,EFCAB2,ERAP1,GCK,GFER,USP19,GLI2,IRAK3,HLF,ICA1,KCNJ5,KIFC3,MAPT,MMP16,ADAM22,NF1,SLC25A23,MAPK7,TCP11L1,FNDC3A,SNCA,FAIM2,HECW1,ZEB1,GPR161" Drug 3754_UP Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AP2A2,KIAA1324,GAS7,ARRB1,FUBP1,CACNA1B,CAMK2B,CD86,CBFA2T2,CDO1,LRIG1,CNTNAP2,ELMO1,SV2B,ING4,MRNIP,NCALD,FGF1,OLFM1,SEMA4D,FYB1,GALC,RUNDC3A,GNAL,SPACA9,GSTM5,SOX21,IL6R,KCNH2,KCNN1,MEF2C,NPTX1,GPR85,PTPRO,SUPT20H,IZUMO4,SLC44A1,TPM2,PDIA2,LAT2,ZNF154,EVI5" Drug 4159_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1B,AP2A2,CDC14B,ARHGDIG,CDK13,ADGRB3,KALRN,CAMK2B,CBARP,CHN2,TAOK2,FAM149A,ARHGEF10,VCAN,C3orf18,MTSS1L,CORO2B,FAM49B,FYN,SIGLEC8,GATM,RUNDC3A,POLL,GRM8,HAS2,IFI16,IL6R,KCNJ5,KCNN1,MID1,PCDH8,GPR85,SAMD9,SNRK,FRMPD1,CNKSR2,SLC11A1,BTBD7,SMARCD3,ADGRL3,SYNE1,ZNF711" Drug 6295_UP Aminophylline [317-34-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,ASIC1,ADCY6,NME5,ALK,AMPH,APC,GAS7,CFLAR,SCAPER,CACNA1I,WHRN,CSF1,CDON,TOM1,DUSP9,PLXNC1,CORO2B,TRAF3IP2,DENND2A,ZNF276,LPAR4,HSF2,IL6ST,KIFC3,MAPT,GIT1,CNOT4,SAMD9,GDPD2,GSTCD,RPS6KA2,SUPT20H,SH3BP2,CNKSR2,TMCC1,SPTB,DDN,ARHGEF9,RPRM,NT5M,KCNAB1" Drug 7348_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADORA2A,NME5,BIN1,APBB2,PPFIA3,ARHGDIG,RASL11B,SLC2A11,SYNJ2,BAIAP3,SOCS6,QKI,NCOR2,SIPA1L1,FAM169A,TBC1D5,PARD6A,DTNA,EGFR,PLXNC1,FER,POLL,GNG4,CNTRL,ATXN2L,PALM,SMIM7,PPARA,PPP5C,PTCH1,RIPOR1,TRAPPC13,SBF1,FBXO11,ZHX3,ARHGEF9,PLCB1,ARC,COBL,SMG6,AP4E1,TK2" Drug 4359_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SYT13,SEMA7A,APOC1,CAMK2B,HIP1R,B4GALT6,TAOK2,QKI,SULT4A1,CNR1,WHRN,VCAN,HEPH,AASS,ELN,RASGRP2,ERBB2,SPEG,FHL1,FYB1,FYN,SRCAP,GPER1,GUCY1B1,LRP1B,PCSK1,CEP41,MAPK7,RELN,PTPRO,RGS12,SLC2A5,SLC8A1,SLC14A1,PEG10,PHLDB1,EXOC7,TNS1,UGT8,WIPF1,LAT2,DPF3" Drug 1179_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "PKP4,APAF1,APBB2,BCL7A,SYNJ2,ARHGEF1,ARMC8,CREM,DZIP3,TM9SF4,FCF1,SUGP2,TUBD1,VPS13B,KAT8,ANKFY1,CAMKK2,CGREF1,LPAR4,KCNJ5,MEF2C,SCAMP5,NF1,CNOT4,PLCD1,POLG,TRAPPC13,RASA3,PREX2,SLC11A1,SNCA,ZHX3,ZBTB43,THSD1,SYN2,EXOC7,TCF4,SIN3B,CRTC1,TMPO,HSPBP1,VLDLR" Drug 3730_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADD2,NME5,FAM135A,AMPD3,EPB41L5,PPP4R4,RASL11B,ADAM23,TAOK2,SH2B1,MYEF2,DTNA,ING4,KAT8,BAIAP2,GPD1,GPD2,GPER1,GSTM5,SOX21,IRF8,KCNH2,ADAM22,NPTX1,PALM,PPARA,PTN,RFX2,RPS20,KCNIP1,RASA3,FNDC3A,SLC11A1,RBM34,TACR1,TRIM2,CRTC1,SLC44A1,PIK3R5,SLC30A4,KCNAB1,KAT6A" Drug 2216_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,NME5,CDC42BPA,APAF1,SLC2A11,ADGRB2,RAB29,CBFA2T2,STOML1,DOCK4,RASSF2,HEPH,RUSC2,MBNL2,VPS13B,NCALD,FGFR1,HPCAL4,EFCAB2,FYB1,GPR37,ITGAM,TAGLN3,ZNF862,PCBP3,NTRK2,P2RY1,TREM2,LRP12,MAPK7,SEMA6D,SH3BP2,FAM214B,KIF13A,TROVE2,SAMSN1,HEY1,UBE3A,PDIA2,XRCC4,SLC17A7,JPH3" Drug 2563_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SYN3,AMH,AMPD3,BIN1,PPFIA4,MPDZ,CD86,CRLF1,CHRNA4,CNTFR,CREM,RGS6,SLITRK5,DRP2,EDN3,FAM13A,EBI3,ENO2,ARMCX1,GPR75,GNAL,STON1,GUCY1B1,TJAP1,KCNF1,MN1,MPP2,MX1,PFKFB3,RASGRF1,RGS12,TCP11L1,CCDC92,IZUMO4,JMJD6,ARHGEF9,SZT2,TRO,ZBTB38,ADAMTS9,PARP11,GAN" Drug 6492_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "CDC42BPA,KCNAB2,GAS7,PPP4R4,ARHGDIG,CDK13,ADAM23,BAIAP3,GREB1,RIMS2,DAPK1,RCAN1,DTNA,CELSR3,MBNL2,TENM1,VPS26C,FGF13,FYN,GALC,POLL,RASSF8,GPR85,PPP5C,SAMD9,RASGRF1,GSTCD,CCDC102B,KCNIP1,MRAS,FRMPD1,ARHGEF40,ZHX3,ATP10B,PHLDB1,SYT5,PHF24,PCDHA5,HIF3A,PARD3,OSBP2,CLIP2" Drug 7146_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASIC1,ADRA1D,AMPD3,CDC42BPA,SHROOM2,RGS11,IQCK,RCHY1,EXOG,EMX2,ETV1,SCARA3,FYB1,TMEM8B,LYVE1,CNTRL,SYNPO,SCIN,INPP5B,MAPT,PDE4B,PDE4D,FA2H,PPP5C,MAPK7,FUZ,AMBRA1,EPN2,SLC9A5,SLC22A4,IFT122,RBM34,DDN,PHLDB1,CHST8,TIAM1,TK2,BHLHB9,CABIN1,LAMP5,KCNAB1,TIGD6" Drug 5516_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASIC1,SEMA7A,LGR5,CDK13,HIP1R,LY86,SNCAIP,DCAF4,SLC12A6,MTSS1L,NCALD,F5,DLC1,FGFR1,FHL1,TPK1,DLL3,INPP5K,GLYR1,TDRKH,CACFD1,IL6ST,IPO5,LIG4,MYT1,PCSK5,NLE1,PLXNB1,STRN3,POLG,GTDC1,TCP11L1,MRAS,SLC2A5,ARHGEF40,ZKSCAN3,HECW1,ERC1,STX1A,PLCB1,CABIN1,HPS4" Drug 6212_UP Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "APOC1,SCAPER,MTMR3,CACNA1I,TAOK2,PLAA,HOMER3,FAM149A,CSF1R,PDE4DIP,BRINP1,EDN3,MBNL2,MTSS1L,DENND4A,F8,GCNT2,GRB10,GRM8,BTN2A1,RNFT2,KIF2A,MAP4,MGAT3,MPP2,NNAT,SLC25A23,PPP2R2B,MAPK7,PRPH,SH3BP2,ABLIM3,SNCA,ZHX3,IZUMO4,CEP68,SYN2,IQCE,KIAA0930,TRIM2,AP4E1,AMACR" Drug 6420_DN Orlistat; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "BRAP,ADORA2A,LTBP4,TRMT9B,DNAH17,MARK4,GYG2,TPP1,SPOCK2,PLEKHA1,TNK2,COQ7,STX2,FGFR1,PDLIM5,AHDC1,POLL,PRRC2B,RASSF8,ELOVL5,LIFR,MAP4,SCAMP5,ZNF862,NF1,SLC11A2,STRN3,ZDHHC14,KIRREL1,STUM,MRAS,SLC12A4,CDK5RAP2,KDM4B,DOP1A,SPTB,CEP68,PCDHA5,CABIN1,TNS1,ZNF32,DPF3" Drug 4704_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASIC1,LGR5,PLA2G4C,ARHGEF1,CACNA2D2,ASIC3,QKI,SULT4A1,CRMP1,CSF1,GIT2,ZNF804A,EDNRB,VPS13B,SPEG,RRAGB,KHDRBS3,GLYR1,RAB30,TDRKH,CACFD1,GSN,INPP1,INPP5B,JAK2,MMP16,CNOT4,P2RY1,PLCB2,C1orf54,CCDC25,MRAS,PHLDB1,STX1A,SYP,KIAA1107,DOCK9,PCDHA6,TNS1,CDK20,ZKSCAN5,NT5M" Drug 6668_DN Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "OGT,CDK10,ZBTB10,ARHGAP33,ARMC8,WHRN,AATK,VCAN,PDE4DIP,ARHGEF4,SUGP2,TENM1,COQ7,ERCC2,ANKMY1,FGFR1,IQCG,SEMA4D,DENND2A,ERAP1,STON1,HLF,SYNPO,TJAP1,IL6ST,MAPT,NF1,CNOT4,MAPK7,REV3L,RPS6KA2,ATXN7,ASAP3,TMCC1,IQSEC2,SYT1,SYNE1,DOCK9,GPR161,CABIN1,TNS1,SENP7" Drug 5815_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "APBB2,DDO,KIF1A,ASIC3,CNOT8,NRXN3,IQCK,AATK,DCAF8,DMD,DUSP9,MBNL2,IRAK4,IGSF6,TBC1D16,ZNF589,TRMO,SYT17,GLI2,LPAR4,GPER1,MAPT,ADAM22,TAGLN3,LYRM9,ZNF862,NF1,PPP5C,RGS12,NEK11,FNDC3A,PKNOX2,KDM4D,MYH15,SNCA,CEP68,MCF2L,TNS1,RPRM,WIPF1,EVI5,MPPE1" Drug 2732_DN Iopamidol [60166-93-0]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ABHD6,BRAP,ADRA1D,AP2A2,MTUS1,SRPX,FAM131A,NUMB,FUBP1,EPS15L1,AKAP7,NRG2,SH2B1,DZIP3,PPP1R16B,DBN1,FCF1,TUBD1,PIPOX,F5,AGAP2,SEPT9,GPR75,TJAP1,KPNA5,MAP4,AFF1,MYT1,PCDH9,PLTP,ZSCAN32,ZCWPW1,SEC14L1,ZNF821,FAM102A,SLC11A1,DDN,LHPP,ADGRL3,TK2,CLIP2,MAP3K12" Drug 4986_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SEMA6A,AMPD3,ADAM23,ADAM15,BCL7A,CACNA1I,BAIAP3,ARHGEF1,ARHGAP33,HOMER3,CNTN1,CSF1R,CSNK1E,SIPA1L1,SPOCK2,MFAP3L,DTNA,CORO2B,FGFR1,GLYR1,ICA1,KCNF1,KCNH2,MAP2,MAP4,NELL2,NF1,RETREG1,ZSCAN32,RGS12,TCP11L1,SEC14L1,SH3GL3,PKNOX2,COA1,IQSEC2,RGL1,TNS2,PCDHA5,HIRA,ADAMTS9,MPPE1" Drug 2292_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ALCAM,CDC42BPA,GAS7,DNAH17,RASL11B,RGS9,GYG2,CACNA1I,AKAP7,SNCAIP,SEC14L5,DAPK1,ERCC2,SPEG,NRN1,FGFR1,TPK1,SRCAP,LYVE1,LPAR4,BACH2,KPNA5,ADAM22,MX1,NNAT,NPTX2,CLDN11,PFKFB2,MTRF1L,RELN,GDPD2,PTCH1,KCTD17,SH3BP2,CXXC4,SNCA,CDK19,SPART,PCDHA5,FAM155A,ADAMTS9,KCNAB1" Drug 7374_UP Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "RALGAPA1,NDRG2,MTUS1,ALK,KCNAB2,GAS7,DDO,MADD,ADGRB2,C5,CACNA2D1,SLC16A4,ARHGAP33,ARHGEF10,BRINP1,DMPK,FAM13A,DENND4A,ETV1,CORO2B,FGFR1,BAIAP2,FYB1,GFER,KCNMB4,SPACA9,FAM69A,MAPT,NF1,PIK3R1,PTPRE,PTPRH,ENOX1,TRAPPC13,MRAS,DZIP1,KDM4B,GPR161,ZKSCAN5,HIRA,SEMA3B,UBE3B" Drug 6076_UP Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "LTBP4,ALK,BIN1,RGS9,LDLRAD4,HAP1,RUNX1T1,CLDN10,HAPLN1,NCOR2,SNCAIP,SEC14L5,SNPH,SPOCK2,ZNF391,REEP2,OGA,SRCAP,GNAO1,PRUNE2,ADAMTS13,GSTM5,KCNH2,MAP4,MMP17,TAGLN3,CNOT4,P2RY1,TREM2,RETREG1,FXYD1,PURG,PPP5C,PRKCB,PSD,RASGRF1,RGS12,SLC2A5,PKNOX2,TCF4,SLC44A1,UBE3A" Drug 2347_UP Tropicamide [1508-75-4]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1D,BIN1,DNAH17,SYNJ2,PPP1R16B,DAPK3,CELSR3,MRNIP,COQ7,RRAGB,GAA,SEPT9,INPP5K,LPAR4,ADAMTS13,GUCY1A1,SCIN,KCNJ5,MID1,AFDN,SLC11A2,NTRK2,OPRL1,PPP1R1A,LRRN3,ZCWPW1,KHDRBS2,SBF1,CXXC4,SNCA,NFASC,ATP10B,SYP,TACR1,SZT2,GPR161,TIAM1,AMACR,ZBTB38,MAP3K12,KCNAB1,PCBP4" Drug 3381_DN Niacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "BIN1,APC,FAM131A,MARK4,NUMB,BCL7A,BAIAP3,CA4,STOML1,WHRN,PHF14,PPP6R2,GIT2,STX2,PDLIM5,PRELID3A,SEPT9,IL6R,KCNJ5,SMAD1,MATK,CDK18,STRN3,PPP3CC,PRKAR1B,MAPK10,GRAMD1C,WDR25,TRIM68,TCP11L1,RASA3,SMARCD3,KDM4B,ZHX3,CDK19,TBCEL,SMG6,TPM2,PDIA2,VGF,VIPR2,EMSY" Drug 3287_UP Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ALCAM,CDC42BPA,PTCH2,CACNA1I,FOXN3,RAB33A,NCOR2,CSF1,CSF1R,DCAF8,BRINP1,MED12,ALDH1L1,POLL,STON1,GPER1,GRIK5,ATXN2L,SMAD1,MMP17,ADAM22,MX1,NPTX2,MINDY2,PRKCB,ZMAT4,RGS12,ASAP3,ABLIM3,KIF13A,ZC3H13,ARHGAP26,SYN2,TRIM2,SZT2,DOCK9,PCDHA6,HEY1,TNS1,SPHK2,SLC30A3,PLSCR4" Drug 5637_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADORA1,ADRA1D,BIN1,PPP4R4,PDE8B,GYG2,CACNA1I,LDLRAD4,HAP1,CAMK2G,CBFA2T2,SCARB1,CLGN,STOML1,QKI,SULT4A1,NRG2,CRY2,RCAN1,DTNA,OPTN,EGFR,FAM49B,FYN,SRCAP,RAB30,IL6R,KITLG,AFF1,NF1,NPTX1,PDE1C,GRAMD1C,BTBD7,TROVE2,PLCB1,CABIN1,ZKSCAN5,ZFP37,ZNF711,SLC17A7,ADAMTSL3" Drug 4645_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,APC,ADGRB2,RGS9,BMP7,SYNJ2,BAIAP3,CFAP410,SLC16A4,RAB26,RGS6,MYEF2,C2CD2L,TOM1,MTSS1L,ANKMY1,EZH1,OLFM1,FGFR3,FLT1,NEU3,GLI2,TOX3,POLL,GNAL,STON1,STMN2,GRM8,LAMA2,MBNL1,ADAM11,OPRL1,PCSK5,PPP1R1A,PTPRG,SLC2A5,ZC3H13,SYT5,TACR1,TRO,KCNK12,MKRN3" Drug 2144_UP Protoveratrine A [143-57-7]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADORA1,MTUS1,CDC42BPA,APAF1,APBB2,ARRB1,KIF1A,DCAF4,CELSR3,MBNL2,NCALD,FGFR1,HPCAL4,PRELID3A,GSTM5,ATXN2L,KCNN1,MAP4,MAPT,MEF2C,ZNF862,PLCD1,CCDC40,RFX2,RGS4,RGS12,KCTD17,RNASEL,TCP11L1,MAP6D1,SEMA6D,CPEB3,KDM4B,IZUMO4,SPTAN1,TSPYL2,SS18,CRTC1,VGF,SPHK2,KCNAB1,ADAMTSL3" Drug 2693_DN rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "TRMT9B,APC,LGR5,CACNA1G,LDLRAD4,PLAA,NCOR2,ARHGAP32,BRINP1,RUSC2,CDON,MBNL2,ELN,MTSS1L,ST3GAL6,ZNF44,INPP5K,GATM,RUNDC3A,ATXN2L,ICA1,MAP4,MGAT3,AFDN,MYCN,MYO6,WDR25,ZSCAN32,KHDRBS2,CCDC92,ANKRD6,SLC6A8,IZUMO4,ARHGAP26,IQSEC2,ARHGEF9,TNS2,LMF1,CLIP2,XRCC4,ZNF711,PCBP4" Drug 3563_DN Estriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADCY6,BRAP,DOC2A,PPFIA3,CDK10,BCL7A,CFLAR,GYG2,SOCS6,AKAP7,SOCS5,GIT2,ZNF804A,MFAP3L,DNM1,ING4,CDKL3,TPK1,CNTRL,INPP5B,MBD1,MPP2,NEK1,NF1,OGG1,PLXNB1,MBOAT7,MINDY2,PRPH,ZNF821,SH3BP2,AMBRA1,CCDC88A,CDK5RAP2,KDM4B,ZHX3,SS18,ST5,SMG6,AP4E1,CABIN1,GDPD5" Drug 5731_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SPARCL1,APBB2,APC,NRP2,ST3GAL5,BTK,GYG2,SLC16A4,SCARB1,HOMER3,ABCG1,CSF1R,PHF14,PYGO1,HS3ST2,HIPK3,FGF12,DCTN2,SIGLEC8,SYT17,ALDH1L1,SRCAP,GFER,GRIK5,SOX21,ITGA7,PRKAR1B,CCDC40,RFX2,ARHGEF40,IZUMO4,SPTAN1,SYN2,MCF2L,TCF4,PCDHGA10,FAM189A1,TNS1,TUBB1,RPRM,KCNAB1,FAM13C" Drug 7246_DN Etodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "BIN1,CFLAR,SYNJ2,HIP1R,CCNT1,EPS15L1,SMARCAL1,CSNK1E,OSBPL3,PPP6R2,USP6NL,DLC1,FHL1,EFCAB2,CINP,FAM49B,TRAF3IP2,GFER,HMGCR,DHX35,HSF2,IFI16,MIA2,NEK1,NFYA,ELOVL2,PTN,CASC3,CCDC88A,SMARCC2,DOP1A,SPATA7,KDM4C,STX1A,VPS13A,EXOC7,FBXW11,KIAA0930,TK2,TNS1,TRPM2,PCBP4" Drug 2109_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "MARK4,ADAM15,MPDZ,ST3GAL5,MYRF,KYAT1,TBRG4,RCBTB2,HINFP,VCAN,SOCS5,PDE4DIP,KLHL3,ABCC5,EGFR,SPEG,RACK1,ZNF589,GLUL,AGFG1,IFI16,SHISAL1,KHK,IPO5,MATN3,PPP3CC,MAPK7,BCAS3,GTDC1,ASAP3,ZC3H13,CAMTA2,SS18,IQCE,TCF4,KIAA0930,ZNF34,CABIN1,ZNF32,NDRG4,PDSS2,AAAS" Drug 4177_UP Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "BIN1,APAF1,APBA2,GAS7,AQP6,CDC14B,ATP1A3,KSR1,MTMR3,CAMK2B,CAST,KCNAB3,TPP1,AKAP6,VCAN,CNTNAP2,CDON,RASGRP2,F5,CORO2B,ZNF589,AGAP2,FYB1,SRCAP,PCDH17,GUCY1A1,GUCY1B1,MID1,NPTX2,OGG1,CEP41,ELOVL2,KLHDC8A,CNKSR2,SLC11A1,SMARCA4,SP2,SYN2,PCDHGB6,SLC35G2,TRIO,NT5M" Drug 5742_DN Ethacrynic acid [58-54-8]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AP2A2,MTUS1,EP400,ARNTL,STX16,ADAM15,SYNJ2,BAG4,CRY2,SLITRK5,MFAP3L,ING4,TNK2,DENND4A,FER,FGFR1,CGREF1,MSL3,PRRC2B,DIDO1,MAN1B1,IFI16,MPP2,MT1M,NF1,PLCD1,PRPH,ELOVL2,GTDC1,RPS6KA2,ASAP3,SLC14A1,SNCA,ZBTB43,SS18,KANK1,KLHL7,TCF4,KIAA0930,CHST8,XRCC4,KAT6A" Drug 5325_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ABR,RIPK1,CFLAR,SCARB1,PLEKHB1,ENTPD4,AKAP12,GIT2,RCAN1,CELSR3,SUGP2,MRNIP,EPB41L2,COQ7,ANKMY1,CELF1,AHDC1,KIF2A,MAP4,MBD1,OPA1,PDPK1,PRODH,PRPH,PTK2,QDPR,RIC8B,SGK1,ABLIM3,SIRT2,SLC22A4,KDM4B,SPTAN1,ARHGEF9,TBL1X,BHLHB9,KAT6B,CABIN1,CDK20,SSBP2,VGF,AAAS" Drug 7539_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "MARCH3,NRP2,SCAPER,RCBTB2,SOCS6,CNOT8,HOMER3,MRNIP,CELF1,OGA,USP19,FAM69A,IPO5,LSS,MAPT,ADAM22,PLCD1,PTPRE,BEND5,RFX2,ZNF331,FAM214B,SMARCD3,TMCC1,SP4,PBLD,ELOVL4,TTBK2,PLCB1,SYT1,EXOC7,CRTC1,BHLHB9,TNS1,TPM2,FAM155A,LMF1,WIPF1,XRCC4,FIP1L1,EPM2A,PHTF2" Drug 4334_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,ASIC1,TRMT9B,APAF1,ARRB1,BAIAP3,HAP1,RUNX1T1,CLCN3,CNTFR,RIMS2,RIPOR2,DTNA,NCALD,PTK2B,AGAP2,PADI2,AGFG1,IFI16,IL6ST,KCNN2,MAP4,TM6SF1,MMP16,ADAM22,NF1,NFIX,PFKFB4,PIK3R1,STRN3,PRKAB2,CEP41,ACSS3,RFX2,KIRREL1,DICER1,SLC44A1,TMPO,TNS1,VSNL1,KCNAB1,KAT6A" Drug 6125_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADORA1,DOC2A,AMH,BIN1,ANK2,FGD2,APOC1,CDC14B,MTMR3,CACNA1I,CBFA2T2,CREM,ABCG1,SPOCK2,SV2B,HEYL,SRPK3,RASGRP2,SCARA3,CAMKK2,PCLO,INSM1,MT1M,NRCAM,PPP2R2B,RELN,PTPRH,RGS4,NEK11,SALL1,SCN8A,GALNT10,PREX2,SLC9A5,CXXC4,TMCC1,SYT5,TCF4,DOCK9,SPHK2,ZNF225,PLSCR4" Drug 2442_DN Calciferol [50-14-6]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "BIN1,CDC42BPA,APOC1,LDLRAD4,HIP1R,QKI,IQCK,ARMC8,CREM,OSBPL3,ZNF337,DGKG,RUSC2,CNNM1,CELSR3,PLXNC1,RASGRP2,CDKL3,VPS26C,ZNF589,AGAP2,GAA,SRCAP,LILRA2,ELOVL5,SMAD1,MAP4,MYO7A,ZNF862,PRKAR1B,PTCH1,ZCWPW1,EMID1,GALNT10,MRAS,FAM102A,FAM214B,SLC6A8,TMCC1,STX1A,TRPS1,LMF1" Drug 6472_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AK2,PPFIA3,CDC14B,PLA2G4C,DNAH17,MARK4,LDLRAD4,MAGI1,CRLF1,B4GALT6,NECTIN3,ENTPD4,GREB1,PPP6R2,TMCC2,TOM1,CNNM1,FGFR1,FAM49B,OGA,GNG4,FERMT2,TDRKH,STON1,CNTRL,GRB10,MGAT3,NELL2,NF1,P2RY1,PRPH,ELOVL2,FBXW7,SBF1,DOK5,CLASP2,NXT2,ARC,CABIN1,VGF,XRCC4,ACTR3B" Drug 6083_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AMH,GAS7,PLA2G4C,ALDH7A1,CA4,RUNX1T1,CDH2,CSF1,ARHGEF10,IPCEF1,DCAF4,SPOCK2,DTNB,ELN,RASGRP2,FGFR1,SRCAP,PRUNE2,LPAR4,PCLO,ADAMTS13,GRM2,GSN,SOX21,ITPKA,KCNB1,KIT,TAGLN3,MX1,NNAT,PCDHGC3,PFKFB2,SERPINI1,C1orf54,ENOX1,ZNF493,ZMAT4,SH3BP2,FAIM2,CRTC1,FLRT2,KCNAB1" Drug 6379_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "RALGAPA1,ADCY6,PKP4,BCAS1,PPP4R4,SLC2A11,BACH1,ASIC3,CHN2,PICK1,ENTPD4,ERC2,PYGO1,DTNA,FCF1,FRY,CELSR3,EGFR,ZNF391,FGF1,FGFR1,ERAP1,CPLX2,RUNDC3A,POLL,IRF8,KCNB1,KIFC3,SERPINI1,NECAB2,MINDY2,CNTLN,ZSCAN2,ZNF671,ASAP3,SLC11A1,DDN,LHPP,SYT1,DMXL2,XRCC4,ZBTB14" Drug 3535_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AK2,CDC14B,SOCS6,SULT4A1,SH2B1,PDE4DIP,HDAC4,RUSC2,TOM1,TSPAN5,EIF4G2,HSD17B14,STX2,ACSL4,FHL1,FLNC,DISC1,GRIK5,INPP1,KCNH2,MEIS1,NNAT,OGG1,PPARA,TMEM104,ZCWPW1,RGS3,SEMA6D,ZHX3,UNC5B,THSD1,PHLDB1,RPGRIP1L,ZNF34,SLC44A1,TRIO,VLDLR,WIPF1,UBE3B,SMIM8,PHTF2,RNF170" Drug 326_UP rapamycin; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ACADM,ACTN1,AGT,C1QTNF1,SPOP,SYT13,ARNTL,NRP2,KRIT1,CBFA2T2,HINFP,GPRASP1,JAKMIP2,RASGRP1,MBNL2,OLFM1,B4GALNT1,RAB40B,ICA1,KTN1,L1CAM,LAMP2,AFF1,ADAM22,PTOV1,NEK1,CCSER2,PLCD1,PPM1B,MAPK10,KDM4B,TSNAXIP1,DBNDD2,LMO3,VPS13A,COBL,ANKRD28,CLASP1,TRIO,ZIC1,MAP3K12,MPPE1" Drug 5426_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NME5,AK2,ALCAM,MADD,KIF1A,CFLAR,BAIAP3,CLGN,TAOK2,ABI3BP,CRY2,NCOR1,SIPA1L1,TBC1D5,DAPK3,EXOG,DTNA,EIF4G2,FHL1,IQCG,RAB30,IL6ST,INPP5B,MAPT,MBD1,KITLG,LYRM9,NTRK2,LRP12,MAPK7,ZSCAN32,GTDC1,RNASEL,SYBU,ANKRD6,PPP4R3A,RBM34,KIAA0930,PARD3,CLDND1,EPM2A,PHTF2" Drug 5071_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "N4BP2L1,BAIAP3,CACNA2D2,CHRNA4,RIMS2,ELN,DENND4A,F5,REEP2,OLFM1,FGFR1,AGAP2,SIGLEC8,GPR75,GNG4,KCNN1,NOVA2,PDE4A,PDE4D,PIK3R1,PPARA,MINDY2,PPP1R1A,PPP2R2B,LRRN3,GRAMD1C,PID1,KHDRBS2,CRTAC1,RGS12,KCTD17,SLA,PKNOX2,FAIM2,HECW1,RBM26,PLCB1,ARC,TRIM2,CHST8,THRA,CABIN1" Drug 3676_DN Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1D,C1QTNF1,C1QTNF3,AMPD2,APC,CDC14B,MARK4,NUMB,SLC4A4,SCAPER,KYAT1,SYNGR3,CACNA2D2,ARHGAP22,EPS15L1,CNTFR,IQCK,SLITRK5,HDAC9,ANKMY1,SPACA9,ELOVL5,SHISAL1,TJAP1,KHK,PCDH9,PIK3R1,CNNM2,PTN,CCDC40,DZIP1,PPP4R3A,TROVE2,VPS13A,ARC,KIAA1107,TIAM1,SMUG1,RPRM,MAP3K12,PLSCR4,KAT6A" Drug 7287_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "PPP4R4,CDK13,MARCH3,DNAH17,BMP7,SCAPER,RAB26,HOMER3,PDE4DIP,CNTNAP2,SPOCK3,AASS,ING4,ANKMY1,EZH1,FGFR1,TRMO,ZNF44,SRCAP,SPACA9,ATXN2L,ELOVL5,TJAP1,SCIN,INPP5B,KHK,KIFC3,MIA2,RIPOR1,TMEM231,GTDC1,FNDC3A,ARHGEF40,SNCA,SOX15,IQSEC2,THSD1,SS18,TNS2,CRTC1,RPRM,DPF3" Drug 2231_DN Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NDRG3,NDRG2,APBA2,SEMA4G,ARHGDIG,MTMR3,GYG2,C5,PPP6R2,SEC14L5,ARMCX2,ZNF804A,MFAP3L,TMCC2,CDON,CELSR3,ZNF589,SEPT9,GCNT2,COPS8,POLL,GSTM5,TJAP1,MAN2A2,MBD1,MSI1,CNOT4,SLC25A23,NEK11,FNDC3A,SOX3,ARHGAP26,SPTAN1,LHPP,WSCD1,SLC44A1,TIAM1,CABIN1,TRIO,WIPF1,SPHK2,SEMA3B" Drug 7330_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADCY6,AP2A2,ALCAM,APOC1,MADD,CDK13,CFLAR,ST3GAL5,CA12,CREM,NCOR1,RIMS2,DBN1,TMCC2,DTNA,MFSD10,VPS26C,SEMA4D,INPP5K,MSL3,GRB10,LMO2,MAP4,NCAM2,PCDH9,LRP12,PRKAR1B,PRPH,ELOVL2,GSTCD,SAFB,GALNT10,KDM4B,SS18,MCF2L,SZT2,TMEM121,CABIN1,VIPR2,DNALI1,HPS4,KAT6A" Drug 5766_UP Skimmianine [83-95-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADD2,PKP4,SLC4A4,KIF1A,SCAPER,CHN2,AKAP6,AKAP5,CSNK1E,SUSD5,ARHGEF4,SPOCK2,DBT,ARMCX2,SV2B,SPOCK3,EDIL3,EDNRB,ING4,PRUNE2,GRIK5,IRF8,MARK1,MSR1,TAGLN3,MYT1,PFKFB4,CEP41,RGS3,RNASE1,TCP11L1,DZIP1,OGDHL,DOK5,SSTR2,SYN2,ICAM5,LAT2,ZNF24,ZNF45,ADAMTS9,KCNAB1" Drug 4133_DN "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NDRG2,LTBP4,DOC2A,SEMA7A,APOC1,MARK4,CFLAR,BMP7,ASIC3,PLEKHB1,STOML1,CPS1,CRMP1,DBN1,ING4,ERCC2,ZNF589,FGFR1,KHDRBS3,DISC1,RUNDC3A,GPER1,PCLO,KCNQ3,GIT1,SERPINI1,PLXNB1,MAPK10,NKAIN1,RGS12,SEMA6D,FERMT1,LIMS2,TSNAXIP1,THSD1,ARC,EXOC7,TBCEL,TNS2,CABIN1,NDRG4,UPF3A" Drug 4708_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,ADORA2A,AK2,SEMA6A,BIN1,NUMB,CBFA2T2,ARHGEF2,TAOK2,AKAP7,LRIG1,ARHGEF10,DCAF8,BRINP1,JAKMIP2,MFAP3L,ST3GAL6,FHL1,SEMA4D,MSL3,GRM8,HNMT,INPP5B,KPNA5,LIG4,LMO2,NF1,NFYA,PRKAR1B,SEC14L1,ANKRD6,BTBD7,SNCA,ARC,SMG6,ZEB1,THRA,PARD3,VIPR2,ZNF74,DNALI1,EVI5" Drug 3338_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NDRG2,KIAA1324,APOC1,PRX,PLA2G4C,ATP2A2,CFAP410,HAP1,RUNX1T1,ARHGEF2,KCNAB3,PDE4DIP,CNTNAP2,SPOCK2,DTNB,MBNL2,C3orf18,ERCC2,PIPOX,F5,DLC1,OLFM1,AFF2,KHDRBS3,NEU3,ALDH1L1,GLYR1,LPAR4,GRIK5,NXPH3,TJAP1,IL6R,NEFM,PCBP3,PNMA3,LRP12,RASGRF1,RFX2,COA1,SMARCD3,ATP10B,SLC17A7" Drug 3790_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AMH,ARHGDIG,SLC2A11,ADAM23,CABP1,ABCG1,RIMS2,SPOCK2,DMPK,MTSS1L,DCTN2,CAMKK2,CHL1,ERAP1,RAB30,LILRA2,IRAK3,HLF,ICA1,KCNF1,KCNH2,KCNN1,LSS,MBP,MSI1,ADAM22,NEFM,NPR2,PCBP3,NTRK2,P2RX7,GPR85,PRKAR1B,CCDC40,SLC11A1,FNBP1,SSTR1,OBSL1,THRA,TPM2,CA14,SPHK2" Drug 6637_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ACHE,ADD1,ALK,ADGRB2,BMP7,CACNA1G,HAP1,CLDN10,ARHGAP33,CHRNA4,ENTPD4,CNTNAP2,MAML1,DUSP9,EDN1,ING4,AGAP2,NEU3,ALDH1L1,PRUNE2,GRIK5,IL6ST,KCNB1,NF1,CNOT4,PALM,GPR85,ZSCAN32,PTPRB,TMEM231,ENOX1,KCTD17,EMID1,SLC9A5,KDM4C,SPTB,ATP10B,PHLDB1,SYT1,LAT2,ZNF24,KCNAB1" Drug 5836_DN Streptozotocin [18883-66-4]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ABHD6,AP2A2,APBB2,APLP1,CASK,PDE8B,LHX2,WHRN,CSF1,SPOCK2,RHOBTB1,COQ7,CDKL3,EZH1,F8,DCTN2,TRMO,COPS8,MAN1B1,HNMT,INPP5B,SCAMP5,MYO6,CCSER2,KCTD15,PLCD1,FA2H,TMEM104,RIC8B,MCMBP,FAM102A,KIF16B,CDK5RAP2,SNCA,UNC5B,ZBTB43,THSD1,ST5,SYNE2,TRIM2,BHLHB9,NAV3" Drug 4459_UP genistein; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "SPARCL1,SLC4A4,ADGRB1,FUBP1,CAMK2B,CCNT1,TPP1,STOML1,LY86,ERC2,RIMS2,CHRDL1,BAIAP2,ALDH1L1,IRAK3,ITGA7,KCNF1,LMO2,NELL2,PDE4B,ENPP2,CEP41,PRPH,PTPRN2,KHDRBS2,RGS3,RNASEL,KIRREL1,TCP11L1,KCNIP1,FRMPD1,PREX2,KANSL3,SLC8A1,SLC11A1,SP4,PLCB1,KLHL4,CRTC1,THRA,LAT2,NLRP3" Drug 6735_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AP2A2,ADGRB2,BMPR1B,BAIAP3,CFAP410,CAPN3,DLGAP1,VAX2,ABCG2,COL9A3,IPCEF1,ARHGEF4,SPOCK2,EDN3,ERBB4,APC2,AGAP2,CSPG5,SIGLEC8,GPD1,PRUNE2,TDRKH,ICA1,ADAM11,ADAM22,NTRK3,P2RX7,GPR85,PPP5C,WDR25,ZFP30,SLC11A1,SPART,SYT5,TACR1,PCDHGB6,TLR4,SLC30A4,EMSY,DNALI1,NLRP3,JPH3" Drug 7496_UP Suramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASPHD1,AP2A2,DOC2A,APLP1,PPFIA3,CDK13,MARCH3,NCOA1,ADGRB2,CFLAR,CAMK2G,SRSF11,VAX2,CDON,CELSR3,EIF5,C3orf18,NCALD,CDKL3,ANKMY1,AGAP2,COPS8,POLL,TJAP1,NEK1,CNOT4,NLE1,PPP5C,CNNM2,CARF,EMID1,SYBU,SLC6A8,ST5,TACC1,PARD3,TRIO,PLPPR2,MAP3K12,HPS4,PCBP4,UBE3B" Drug 1511_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ALCAM,CDC42BPA,GAS7,APLP1,PLA2G4C,CACNA1I,LDLRAD4,CALB1,CALB2,SOCS6,TAOK2,CNR1,RCHY1,DCAF4,HDAC4,DGKG,MFAP3L,LYPD1,USPL1,RCAN2,SRCAP,ADAMTS13,GSN,MATK,ZNF862,PLCB2,EMID1,CXXC4,SNCA,PDZD2,ARHGAP26,SAMSN1,SSTR2,TACC1,SZT2,DICER1,ZKSCAN5,FAM155A,WIPF1,LAT2,REEP1,MPPE1" Drug 5876_DN Convolamine hydrochloride [500-56-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ABHD6,AMT,KCNAB2,CDC14B,ALDH7A1,CFLAR,CCNT1,LARGE1,LHX2,QKI,TM9SF4,DBT,DCTN1,SGSM2,PLXNC1,EPB41L2,VPS26C,SEMA4D,TPK1,TRAF3IP2,GAD1,SRCAP,COPS8,BTN2A1,DHX35,MEIS1,MMP16,MPP2,TAGLN3,SLC11A2,CCSER2,POLG,GTDC1,MAP6D1,PEX26,INTS9,ATMIN,TCF4,BHLHB9,TRPM2,EMSY,HPS4" Drug 1568_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NDRG3,NDRG2,ADCY6,ARNTL,N4BP2L1,RIPK1,BACH1,BMP7,WASF1,LDLRAD4,KRIT1,ARHGAP33,RNF14,CSF1R,DCAF8,PTK2B,EFCAB2,PDLIM5,DISC1,PRRC2B,ADAMTS13,PRDM5,ITGAM,KCNH2,KTN1,MAP4,MBD1,PALM,PLCD1,PRPSAP2,ZSCAN32,R3HDM2,KBTBD4,DOK5,POGZ,PHF24,TNS1,CA14,SSBP2,HIRA,XRCC4,DPF3" Drug 7219_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADCY6,FAM131A,MADD,NUMB,CFLAR,PTBP2,KYAT1,KRIT1,CRLF1,TAOK2,QKI,HOMER3,CSNK1E,GREB1,GPRASP1,DCAF8,FBXL5,LYPD1,SGSM2,MED12,EDNRA,SUGP2,EGFR,MRNIP,STX2,ERBB2,DISC1,COPS8,PRRC2B,BTN2A1,MAP4,PDE4A,CNNM2,RIPOR1,CEP97,RPS6KA2,SBF1,MAPKBP1,CLASP2,CAMTA2,EXOC7,TBL1X" Drug 2251_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NME5,APBB2,GAS7,PPP4R4,DNAH17,SLC4A4,CFLAR,CA4,CACNA2D2,SOCS6,CNTN1,GREB1,DPH1,DTNA,PLXNC1,CDKL3,RRAGB,ACSL4,SRCAP,RAB30,GSN,ELOVL5,IL6ST,KCNH2,LMO2,MMP16,ADAM22,ZNF862,NF1,NPR2,CDK18,PPP2R2B,TCP11L1,MAPK12,UNC5B,TROVE2,THSD1,KIAA1107,SLC44A1,CABIN1,REEP1,MAP3K12" Drug 4357_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ASIC1,AP2A2,AK2,SEMA6A,AMT,SLC2A11,SYNJ1,SYNJ2,CA4,CA12,HAP1,CAMK2G,KYAT1,PICK1,CSF1,MAML1,DAPK3,MBNL2,ZNF589,SCARA3,IQCG,GAD1,KCNH2,MBD1,MMP16,LYRM9,RETREG1,SLC25A23,PTCH1,TMEM231,RNASEL,FBXW7,RPS6KA2,RASA3,FBXO11,FAM214B,NXT2,TTBK2,WSCD1,BEX4,METTL3,EPM2A" Drug 5415_UP Vigabatrin [60643-86-9]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "AMPD3,APBA2,APC,GAS7,APOC1,MPDZ,BAIAP3,CA4,CAMK2G,CBFA2T2,CHN2,CNTN1,CNTNAP2,USP6NL,EDNRA,DLC1,FGFR3,FHL1,TRAF3IP2,RAB30,PRRC2B,PCLO,GRM8,ITPKB,JAK2,KCNN1,CNOT4,PIK3R1,LRP12,PPARA,GRAMD1C,PTN,ZFHX4,SNCA,RBM34,DOK5,ATP10B,TROVE2,TRIO,UBE3A,WIPF1,SLC17A7" Drug 3995_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "FZD9,ADRA1D,LTBP4,TRMT9B,OGT,NRP2,CACNA1G,LDLRAD4,SLC16A4,MAGI1,TPP1,RGS6,SV2B,ETV1,F5,SRCAP,GNAO1,PRUNE2,KCNN1,KHK,MAP2,NPTX1,GPR173,NLE1,PPP1R1A,PPP2R2B,C1orf54,SUSD4,BEND5,RFX2,SLA,ZNF334,CXXC4,SNCA,SOX15,PLCB1,MCF2L,TNS1,VIPR2,VSNL1,DPF3,JPH3" Drug 7133_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "ADRA1D,PPP4R4,PDE8B,MARK4,ATP2A2,SCARB1,RAB28,HOMER3,CSF1R,OSBPL3,RUSC2,DTNA,MBNL2,ZNF391,SPEG,CDKL3,SCARA3,PDLIM5,OGA,SIGLEC8,GFER,CRCP,MSL3,IL6ST,JAK2,LIG4,MX1,LYRM9,PLCD1,TMEM231,NLGN1,LIMCH1,DDN,SAMSN1,ELOVL4,SYT1,TCF4,NSD1,TRPM2,TRPS1,TFIP11,HPS4" Drug 3641_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.12E-05 1.00E+00 8.55E-04 9.64E-03 42 199 "NME5,BIN1,RASL11B,CLGN,PLAA,STOML1,AKAP6,SH2B1,SNCAIP,CNTNAP2,RIMS2,DMPK,PLXNC1,ELN,NCALD,ZNF589,FER,PDLIM5,DLL3,TMEM8B,GCNT2,GRM8,SMAD1,KITLG,ADAM22,NF1,NNAT,PRKCB,PRPH,EMID1,ASAP3,SLC2A5,SMARCD3,SPTB,ST5,VPS13A,EXOC7,DOCK9,SLC35G2,TRPM2,WIPF1,ADAMTSL3" Drug 5985_DN Norfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "FAM131A,APOC1,PPFIA3,CFLAR,ST3GAL5,SYNJ2,SCAPER,UBE2L6,TAOK2,HOMER3,AKAP7,NCOR1,CNTNAP2,GREB1,KIAA0586,GIT2,SUGP2,IRAK4,ZNF589,RAB30,KCNF1,MAPT,GIT1,LYRM9,NF1,SAMD9,GTDC1,FBXW7,ANKRD6,FAM214B,SPTAN1,IQSEC2,ELOVL4,ASTN2,MCF2L,EXOC7,VIPR2,XRCC4,ZFP37,TFIP11,MPPE1" Drug 4253_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "APBB2,APC,NRP2,CFAP410,PDE4DIP,PLPPR4,DTNA,EDN1,MBNL2,MTSS1L,ETV1,ANKFY1,AFF2,OGA,FYB1,ZNF44,RUNDC3A,GPR37,HSF2,ITPKA,LIG4,LSS,ADAM22,NOVA2,PLXNB1,PPARA,PTPRB,GTDC1,FRMPD1,KANSL3,ELMO2,KIF13A,SS18,SYN2,TRIM2,CRTC1,THRA,R3HDM1,SPHK2,REEP1,EVI5" Drug 7548_UP DNA-PK Inhibitor III; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "ASIC1,ADCY6,MPDZ,BAIAP3,FOXN3,TAOK2,RAB28,CRY2,ABCG1,CTH,DAPK3,SGSM2,DPH1,SEMA3D,OPTN,STX2,ERCC2,DLC1,FGF13,FGFR1,BAIAP2,TRMO,PDLIM5,CSPG5,HNMT,ITPKA,MBD1,SAMD9,ELOVL2,PTN,SUGCT,ZNF671,CSRNP3,ASAP3,MYH15,SNCA,SPATA7,KIAA1107,TK2,HPS4,PCBP4" Drug 6704_DN Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "RALGAPA1,CFLAR,MTMR2,KRIT1,TPP1,QKI,HOMER3,PDE4DIP,DZIP3,TBC1D5,DCTN1,FEM1B,FCF1,MBNL2,ETV1,FGFR1,ANKFY1,TRMO,OGA,FYN,TRAF3IP2,IL6ST,LIG4,CNOT4,PLCD1,PPP5C,MAPK7,RAD51D,FAT4,KIRREL1,CLIP1,ZNF667,SPTAN1,SS18,KIAA0930,DICER1,BEX4,PARD3,CABIN1,UBTF,PHTF2" Drug 6643_UP Thioguanosine [85-31-4]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "RALGAPA1,ASPHD1,ACHE,SYT13,AMPH,GAS7,PPP4R4,CACNB4,CAMK2B,DGKI,VAX2,SPOCK2,DTNA,ELN,DLC1,ST3GAL6,FGF1,PDLIM5,SIGLEC8,GFER,STMN2,KCNJ5,KCNN1,LSAMP,ADAM22,NACA,NOVA2,PALM,PDE4A,PPP1R1A,RASGRF1,SCN2B,ZNF334,PDZRN3,RBM34,ZBTB43,SYT5,PHF24,DICER1,AP4E1,KCNAB1" Drug 3773_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "ABR,ADCY6,APC,CDK13,BMP7,ST3GAL5,ABCG2,HOMER3,CRMP1,ZFYVE16,DAPK3,SGSM2,DTNA,FCF1,FGFR1,FHL1,DCTN2,IL12A,INPP5B,PDE4D,SERPINI1,POLG,BCAS3,RAD51D,SUSD4,FUZ,NLGN1,DZIP1,OGDHL,PEG10,ATP10B,SYN2,TBCEL,SZT2,TNS1,SSBP2,VGF,ZBTB14,EPM2A,TIGD6,RNF146" Drug 3015_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "CDC42BPA,CDK10,AZGP1,BAIAP3,THSD7A,HIP1R,RUNX1T1,DGKI,DLGAP2,NRG2,PDE4DIP,DBT,SPOCK3,EXOG,HS3ST2,EDN1,EDN3,PLEKHA1,HSD17B14,FER,AFF2,PRELID3A,GALC,ATXN2L,SCIN,KIT,MYCN,MYH3,NEFM,CNOT4,NTRK2,PDE4A,STRN3,FSD1,PRKAR1B,EPN2,PHF24,FLRT2,WNT7A,ZNF225,GAN" Drug 3213_DN Colchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "APOC1,BCAS1,ARHGDIG,ARRB1,CDK13,MTMR2,SCARB1,TAOK2,AKAP12,LRIG1,PDE4DIP,CTH,GIT2,NR1D2,SLC12A6,FCF1,ING4,OGA,GALC,POLL,HSF2,LIG4,MBD1,KITLG,ADAM22,NFYA,SLC11A2,PCDH9,PDE4A,STRN3,TMEM104,RGS12,RNASEL,TRAPPC13,IQSEC2,TROVE2,PCDHA6,NPL,ZBTB14,REEP1,RNF146" Drug CID000104822 dihydropyridine Stitch 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "ADD1,ADRB2,AGT,AMPH,BIN1,ANK2,ATP2A2,ATP2B2,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2B,KRIT1,LRBA,CACNA2D2,SNAP91,DMD,DMPK,EDN1,EDN3,EDNRA,PRKAG2,ATP2C1,GCNT2,ABCB1,PKD1,PRKACB,PRKCB,QDPR,GLDN,RYR3,CASC3,ADHFE1,MGRN1,TPCN2,KCNAB1" Drug 2093_UP Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "ACHE,STX16,ATP2A2,SYNJ2,SCAPER,CBFA2T2,ARHGAP22,CLCN3,ENTPD4,SEC14L5,SPOCK3,DPH1,EDN3,FCF1,ANKMY1,FGF1,DLL3,FYB1,SYT17,CRCP,SPIN1,LPAR4,ADAMTS6,MMP16,GIT1,ADAM22,TAGLN3,NF1,CNOT4,KCTD15,CNTLN,RIPOR1,C1orf54,ZCWPW1,KIRREL1,ZBTB43,DDN,ASTN2,TCF4,SYNE1,LAT2" Drug 1696_UP Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "NDRG2,ADRA1D,APLP1,CNTN1,WHRN,PHF14,GREB1,ARHGEF4,NR1D2,DTNA,FEM1B,EGR3,HSD17B14,ERAP1,TXNL4A,INPP5B,JAK2,MATK,ADAM22,ZNF862,NF1,TMEM260,SGK1,SH3BP2,SYBU,KDM4C,SPTAN1,PRRC2C,PLCB1,ARC,DNMBP,KIAA1107,TRIM2,RPGRIP1L,CRTC1,SLC44A1,ZKSCAN5,PDIA2,VLDLR,ZNF45,SEMA3B" Drug 6394_DN C75; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "AP2A2,NME5,C1QTNF3,SYT13,CDC42BPA,APAF1,FAM131A,SPTBN4,CDK13,GYG2,LDLRAD4,CALB1,RAB28,PICK1,WHRN,SIPA1L1,RASSF2,MFAP3L,DTNA,HIPK3,ING4,TNK2,ANKFY1,USP21,TRAF3IP2,ELOVL5,INPP1,JAK2,MAP2,MYT1,LRP12,RAD51D,RFX2,STUM,BTBD7,LIMCH1,DOP1A,PCDHGA10,CLIP2,REEP1,KCNAB1" Drug 4067_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "DNAH17,NRP2,MYRF,ARHGAP22,CNTFR,NRG2,NCOR2,MFAP3L,CELSR3,AASS,STX2,ST3GAL6,ZNF44,ERAP1,TMEM8B,USP19,GPER1,GUCY1A1,GUCY1B1,MAPT,NOVA2,ZSCAN32,SH3TC2,RGS4,PREX2,UNC5B,DDN,THSD1,CEP68,TBL1X,TRIM2,RPGRIP1L,PCDHA5,TRIO,HIRA,PLPPR2,VGF,XRCC4,EMSY,UBE3B,TIGD6" Drug 4443_DN "radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "AMPD3,APBB2,APC,ADGRB2,SCAPER,IL33,FOXN3,LHX2,PLAA,AKAP7,AATK,DUSP9,HIPK3,CELSR3,STX2,ERCC2,NCALD,SYT17,ICA1,SHISAL1,JAK2,GIT1,NF1,CNOT4,PFKFB2,PLCB2,RGS4,RXRA,ATXN7,ARHGEF40,TSNAXIP1,DDN,SMG6,ZEB1,CABIN1,TNS1,UGT8,XRCC4,ZNF24,SEMA3B,PHTF2" Drug 2523_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.36E-05 1.00E+00 8.89E-04 1.00E-02 41 193 "NDRG2,BIN1,CDC42BPA,APBB2,PPP4R4,PLA2G4C,ST3GAL5,HIP1R,CNTNAP2,DZIP3,GSDME,CNNM1,TLR7,REEP2,FER,FGFR3,GAD1,SIGLEC8,GNG4,STON1,HAS2,MEF2C,PCDH9,PCSK5,CCSER2,GPSM2,SLC25A23,PKIA,FAM184A,EMID1,RPS20,PPM1E,ANKRD6,TMCC1,IZUMO4,SPTAN1,SPTB,RGL1,KIAA1107,DOCK9,ICAM5" Drug CID000003541 AC1MBZ1C Stitch 5.43E-05 1.00E+00 9.02E-04 1.02E-02 70 387 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,PRX,ATP2A2,ATP2B2,ALDH7A1,CACNA1A,CACNA1B,CACNA2D1,CALM1,CAMK2B,CCK,KRIT1,ARHGEF1,LRBA,CHGB,PCYT1B,AKAP5,CREM,CSNK1E,MATR3,DMPK,EDN1,EDNRA,EDNRB,CALCRL,CAMKK2,ATP2C1,CRCP,GPER1,GRM8,TNFAIP8L3,HSF2,MYLK2,KCNB1,MITF,NPY,NPR2,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PIK3C2A,PIK3R1,PLCB2,PLEC,PRKACB,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,PTH1R,MAPK12,SLC9A5,SLC12A2,SNAP25,PLCB1,SYT1,VGF,VIPR2,VSNL1,PLD4" Drug 5841_UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.58E-05 1.00E+00 9.26E-04 1.04E-02 40 187 "ADCY6,ADORA2A,SLC4A4,CFLAR,BAIAP3,NRXN3,CPS1,AKAP12,VCAN,PDE4DIP,DZIP3,DCAF8,ZNF337,GIT2,NRN1,ACSL4,BAIAP2,ALDH1L1,GSTM5,TAGLN3,OXTR,GSTCD,NEK11,TCP11L1,ASAP3,AMBRA1,ABLIM3,LIMS2,ELMO2,TMCC1,DOK5,ARHGAP26,NXT2,ANKRD12,IQCE,ZFPM2,TRIO,VIPR2,WNT7A,RNF146" Drug 5678_UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.58E-05 1.00E+00 9.26E-04 1.04E-02 40 187 "ADORA1,BEGAIN,SLC4A4,MTMR7,LHX2,HAPLN1,NCOR2,CSF1,CNTNAP2,ARHGEF4,ARHGAP24,DGKB,EGFR,EGR3,EIF4G2,COQ7,FYB1,SIGLEC8,SRCAP,LYVE1,GNAO1,TDRKH,GRIK5,SLC2A6,LSS,MEF2C,PPP1R1A,PTCH1,SH3BP2,KDM4B,TRIM2,DICER1,ZNF34,PARD3,TPM2,TRO,VLDLR,WIPF1,KCNAB1,EPM2A" Drug 3077_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.58E-05 1.00E+00 9.26E-04 1.04E-02 40 187 "ASPHD1,ASIC1,ABHD6,APBB2,SGCE,HIP1R,CHN2,LHX2,ABCG1,SUSD5,PDE4DIP,DZIP3,DOCK4,GSDME,PLXNC1,C3orf18,RASGRP2,STX2,ETV1,TLR7,FGFR1,MAP4,SCAMP5,GIT1,MSI1,MYO6,CNOT4,PCDH9,SERPINI1,PLCL1,TMEM255A,SATB1,CCDC92,SNCA,PEG10,ZC3H13,RGL1,TRIM2,MAP3K12,SLC17A7" Drug 1741_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; HL60; HG-U133A" Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APBB2,APOC1,CDK10,MARK4,ATP2A2,CFLAR,BMP7,CACNA1A,P2RX6,CD86,SOCS6,CHN2,CNTFR,CRYM,INTS1,DAPK1,C2CD2L,TMCC2,MRNIP,TMEM35A,GABRG2,NXPH3,MMP16,MN1,ADAM22,NTRK3,PLCB2,PTN,CCDC40,ZFHX4,FBXW7,TCP11L1,SH3BP2,ZBTB43,PDLIM2,PHF24,ZMAT3,PARD3,CA14,GDPD5,RNF170,DPF3" Drug 1559_UP Spiperone [749-02-0]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "NDRG2,ADD2,OGT,APBA2,KCNAB2,ARRB2,CFLAR,MTMR3,CCNT1,RCBTB2,SRSF11,B3GAT3,DPYSL2,DTNA,ENO2,RASGRP2,IGSF6,CD320,BAIAP2,POMT1,TRAF3IP2,PRRC2B,LILRB4,DIDO1,BTN2A1,MBD1,CLDN11,P2RX7,PALM,PLCD1,MBOAT7,CNNM2,ACSS3,RAP1GDS1,SAFB,SH3BP2,SLC11A1,UNC5B,STXBP1,CHST5,REEP1,EPM2A" Drug 4672_DN Loperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "CDC14B,ATP1A3,ALDH7A1,PLEKHB1,PLAA,AKAP7,SH2B1,CNTNAP2,PLXNC1,AFF2,TRMO,COPS8,CNTRL,HAS2,SHISAL1,JAK2,AFF1,MN1,ADAM22,NDP,NEK1,CNOT4,PDE4B,PIK3R1,PPARA,PTN,ZSCAN32,ZSCAN2,TMEM231,BEND5,KHDRBS2,CSRNP3,FRMPD1,TSNAXIP1,ARHGAP26,DDN,SYNE1,TMEM121,THRA,TIAM1,TK2,WNT7A" Drug 5403_DN Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APBB2,APLP1,PPP4R4,ALDH7A1,MTMR3,B4GALT6,HOMER3,ENTPD4,PDE4DIP,DAPK3,LYPD1,RCAN1,BAIAP2,RUNDC3A,MSL3,KCNMB4,GRB10,GRIK5,PADI2,IL6ST,KCNF1,KCNH2,IPO5,MMP16,GIT1,NF1,RETREG1,MBOAT7,PRKAR1B,PRPH,TMEM231,SH3BP2,FAM214B,RBM34,NSFL1C,MCF2L,FBXW11,TRIM2,AP4E1,TK2,ZNF45,KAT6A" Drug 3904_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ACTN1,ADCY6,SRPX,AMPD3,AMT,GAS7,BMP7,CAMK2B,ARHGEF1,CRLF1,CSF1R,USP6NL,EGFR,PLXNC1,ERCC2,ZNF589,SCARA3,GCNT2,GSN,TJAP1,KITLG,MMP17,ADAM22,NPR2,NPTX1,LRP12,MAPK10,NKAIN1,CCDC40,GTDC1,SBF1,FAM214B,BTBD7,SMARCD3,MAPKBP1,RBM34,ARHGAP26,ZNF34,TK2,EVI5,ITM2C,RNF170" Drug 4088_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASIC1,GAS7,PDE8B,RIPK1,KIF1A,SOCS6,RAB28,RAB26,CNTFR,CRMP1,PDE4DIP,DAPK3,PLPPR4,SGSM2,CELSR3,ETV1,EZH1,GAD1,GLYR1,ICA1,SHISAL1,IL6ST,KIFC3,MATN3,PDE4D,SERPINI1,RETREG1,PLXNB1,PPP5C,CNTLN,ZSCAN2,FAM184A,ZCWPW1,ZNF821,ANKRD6,SLC4A3,LIMCH1,CEP68,ASTN2,TRIM2,EMSY,FZD3" Drug 6521_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADCY6,TRMT9B,OGT,APOC1,BCAS1,PPFIA3,SEMA4G,MARK4,CFLAR,ST3GAL5,PLAA,QKI,WHRN,AATK,KIAA0586,GIT2,MFAP3L,KIAA0753,ENO2,STX2,CDKL3,EFCAB2,CNTRL,SPACA9,HNMT,ITPKB,MAP4,MEIS1,FSD1,PPP2R2B,RNASEL,ZNF821,NLGN1,SS18,NXT2,EXOC7,CDK20,XRCC4,MAP3K12,EMSY,MPPE1,UBE3B" Drug 6034_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "KCNAB2,APOC1,BCAS1,ATP6V0A1,ADAM15,CACNA1I,CA4,USP2,ARHGEF2,SLIT2,CNTFR,RCHY1,SMARCAL1,GREB1,GIT2,PARD6A,DLC1,FHL1,MALT1,GLYR1,GPD2,KCNN2,IPO5,MAP4,MMP16,MPP2,ADAM22,PMP22,PPP5C,RGS12,ZFHX4,GSTCD,TCP11L1,ASAP3,ANKRD6,PHLDB1,PLCB1,ANKRD12,EXOC7,PCDHA6,TK2,KCNAB1" Drug 5679_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "NDRG2,C1QTNF3,GAS7,DDO,SEMA4G,SLC4A4,SGCE,CALB1,FOXN3,TPP1,MYRIP,IPCEF1,PDE4DIP,ARHGEF4,GIT2,DMD,NCALD,SPEG,AFF2,DCTN2,OGA,DISC1,LYVE1,KCNH2,NTRK2,NECAB2,RELN,ASAP3,PREX2,BTBD7,SP4,PEG10,ZC3H13,TRIM2,SYNE1,HIF3A,DICER1,TK2,PIK3R5,WIPF1,ANKS1B,ADAMTS9" Drug 6324_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "AP2A2,MTUS1,EP400,KCNAB2,APLP1,ATP2A2,SLC25A14,TAOK2,QKI,IQCK,NCOR1,ARHGAP32,GIT2,TNK2,VPS13B,ERCC2,DENND4A,SPEG,ST3GAL6,FCGRT,USP21,MAP4K5,HNMT,MAN2A2,SCAMP5,MITF,MT1M,SLC11A2,OCRL,PIK3R1,POLG,RIPOR1,MAPK12,PEX26,KDM4C,STX1A,KIAA0930,PARD3,WBP2,ZKSCAN5,HIRA,EPM2A" Drug 2632_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASPHD1,ADD2,KCNAB2,APLP1,MARK4,N4BP2L1,RGS9,NRP2,CACNA2D1,CAMK2B,TAOK2,CPS1,PDE4DIP,RIMS2,MYEF2,DMPK,EDN3,EIF4G2,NCALD,RASL12,FGFR1,EFCAB2,DISC1,GCNT2,GPR162,RUNDC3A,GSTM5,LMO2,AFDN,MN1,PCDH9,MAPKBP1,DOK5,ZSWIM8,ERC1,IQSEC2,ST5,FAM189A1,AP4E1,TRPM2,SPHK2,DPF3" Drug 4807_DN Nystatine [1400-61-9]; Down 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ABHD6,AP2A2,CFLAR,SLC25A14,SOCS6,QKI,AKAP7,DBT,FBXL5,SACS,SUGP2,EPB41L2,STX2,TRMO,STAU2,ITPKB,JAK2,MEIS2,NF1,CCSER2,STRN3,WDR25,PPM1E,ABLIM3,LIMCH1,KIF13A,ERC1,SPART,ZNF302,NEK4,KANK1,SYT1,FAM208A,DMXL2,SATB2,DOCK9,TMPO,KCNK12,REEP1,UPF3A,ACTR3B,GAN" Drug 6106_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "RALGAPA1,BEGAIN,ARHGDIG,ALDH7A1,NRP2,SCAPER,CACNA1I,LY86,SEC14L5,RASSF2,PARD6A,EDNRA,TENM1,ING4,RRAGB,NEU3,ALDH1L1,PRUNE2,TDRKH,PCLO,SMAD1,MPP2,NF1,CLDN11,PCDH9,PDZRN4,LRP12,PRKCB,GDPD2,TRIM68,RGS12,KCTD17,TCP11L1,SLA,SLC11A1,PDZD2,RGL1,KIAA1107,DOCK9,TNS2,PCDHA6,UBE3A" Drug 2127_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADRA1D,KCNAB2,SEMA4G,MARK4,CFLAR,CCNT1,ARHGEF2,CACNA2D2,HOMER3,NRG2,CSF1,GPRASP1,SPOCK3,FAM13A,ZNF589,SCARA3,GALC,ARFIP1,HTATSF1,PRRC2B,SHISAL1,INPP5B,ITGA7,ZNF862,NPR2,SMIM7,FSD1,PPP5C,SAMD9,NUDT11,SBF1,SIRT2,IFT122,SPTAN1,ELOVL4,CRTC1,THRA,TMPO,SSBP2,WIPF1,ZNF32,ST7" Drug 3014_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "C3orf14,NDRG2,TRMT9B,MARK4,NUMB,ATP2B2,AZGP1,THSD7A,DLGAP1,CHRNA4,LHX2,BRINP1,HEYL,AASS,EIF4G2,RASGRP2,AGAP2,AFF2,GNAL,GNG4,AP4S1,MAP4,MAPT,TAGLN3,MYT1,NNAT,PMP22,MAP6D1,ZNF821,MRAS,ANKRD6,ZNF415,SPTAN1,IQSEC2,ATP10B,WSCD1,RIMBP2,PARD3,CDK20,TRO,FAM155A,OSBP2" Drug 2558_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "AMH,CDC42BPA,PKP4,BACH1,FUBP1,CFAP410,CHN1,CSF1,CSNK1E,VCAN,RUBCN,DGKG,DAPK3,MFAP3L,TMCC2,DTNA,BAIAP2,AGAP2,CAMKK2,GPD2,TJAP1,LAMA2,MAP4,NEFM,NINJ2,CLDN11,P2RY1,PPARA,RGS3,ZFHX4,TCP11L1,ZNF821,RASA3,PREX2,SNCA,SPART,ATP10B,ARHGEF9,PLCB1,SYT5,HIRA,XRCC4" Drug 4387_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADRA1D,BEGAIN,SLC4A4,SGCE,BAIAP3,CFAP410,HAP1,CACNA2D2,FAM149A,OSBPL3,IPCEF1,PHF14,RIPOR2,KLHL3,EDN1,LRRC17,ETV1,EFCAB2,NSG1,FYB1,GAD1,GPD2,STON1,LSS,GPR85,POLG,CEP41,CCDC40,SUGCT,SLC2A5,LIMS2,KANSL3,ZNF334,SNAP25,HECW1,ARHGAP26,CDK19,PHLDB1,TK2,AMACR,LAT2,ITM2C" Drug 4995_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADCY6,ADD2,BIN1,CDC14B,PDE8B,MARK4,SCAPER,GYG2,SGCE,BAIAP3,LDLRAD4,KYAT1,FOXN3,CHN2,CNTN1,CSF1,ARHGEF4,EDN1,DLC1,OLFM1,FGF13,FGFR1,FHL1,AGAP2,PCDH17,GPR75,GPER1,ADAMTS13,ICA1,MID1,FAT4,ZNF493,KHDRBS2,SBF1,SH3BP2,KIAA1107,CRTC1,HIF3A,PARD3,TPM2,ZFP37,SEMA3B" Drug 6690_DN Flucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "CDC42BPA,KIF1A,NRP2,ST3GAL5,KRIT1,IQCK,CNTNAP2,SLITRK5,ZBTB24,SGSM2,CHRDL1,EXOG,TOM1,COQ7,FECH,SCARA3,TMEM8B,GLI2,MUM1,HNMT,FAM69A,PLCD1,PPARA,GRAMD1C,PTN,ZSCAN2,TMEM231,KHDRBS2,KIRREL1,FBXO11,PPP4R3A,SMARCD3,LIMCH1,UHRF1BP1L,DDN,THSD1,CEP68,VPS13A,ZKSCAN5,EVI5,HPS4,KCNAB1" Drug 2642_UP Bisoprolol fumarate; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "RALGAPA1,ADCY6,SEMA6A,AMH,FAM131A,BAIAP3,LDLRAD4,CA4,CALB2,CAMK2B,KCNAB3,CRLF1,CHRNA4,HAPLN1,DCAF4,ARHGAP24,INTS1,EXOG,EIF4G2,IQCG,SIGLEC8,GRB10,ADAMTS13,GRM8,KCNN2,MITF,CNOT4,CLDN11,CDK18,PLTP,PRPH,FNDC3A,PREX2,SMARCD3,MYH15,KDM4C,ARHGAP26,SPTAN1,ICAM5,CHST5,OSBP2,VSNL1" Drug 6659_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASPHD1,ACHE,FAM135A,PPFIA4,ARHGDIG,PDE8B,SLC4A4,RUNX1T1,CHRNA4,FAM149A,CREM,ARHGEF10,RIMS2,INTS1,DGKG,C2CD2L,EDN1,TNK2,EPHB1,NRN1,F5,NEU3,GPR75,CACFD1,SHISAL1,KCNB1,NRCAM,PALM,CDK18,PDE4B,ACSS3,KHDRBS2,RET,FRMPD1,ZNF334,SNCA,ZHX3,SYT5,ZFPM2,SLC17A7,KCNAB1,AP3B2" Drug 6333_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADRA1D,BEGAIN,APC,APOC1,ST3GAL5,CAST,KYAT1,SYNGR3,CACNA2D2,LHX2,ABCG1,AATK,CSF1,CSF1R,CSNK1E,SUSD5,CNTNAP2,PYGO1,LRRC17,FGF1,PDLIM5,SEPT9,SRCAP,ADAM28,GLYR1,ICA1,NFYA,NPTX1,PLCD1,PTPRE,EMID1,SBF1,HKDC1,SLC2A5,SLC11A1,SMARCD3,IFT122,RPGRIP1L,DOCK9,RIMBP2,CDK20,SEMA3B" Drug 4625_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "AMT,KCNAB2,APBB2,ALDH7A1,ADGRB2,SCARB1,SYNGR3,AP4M1,TAOK2,RAB28,QKI,TBC1D5,RUSC2,SGSM2,DTNB,CELSR3,MBNL2,MRNIP,STX2,ST3GAL6,SIGLEC8,USP19,CACFD1,FAM69A,JAK2,MT1M,MX1,PPP3CC,PRKAR1B,ZSCAN2,FAT4,ZNF821,FRMPD1,AMBRA1,TMCC1,RBM34,VPS13A,TMEM121,TPM2,ZNF711,EMSY,SEMA3B" Drug 5879_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ALK,APC,ADAM23,IL33,CAPN3,CBFA2T2,SCARB1,QKI,SULT4A1,COL9A3,VCAN,GIT2,TOM1,RGS17,SYT17,KCNMB4,TDRKH,PTPRT,SCIN,KCNQ3,ADAM22,NPTX1,PRKAR1B,ZSCAN32,RIPOR1,TMEM231,ACSS3,FAT4,BEND5,FBXW7,TCP11L1,DZIP1,ANKRD6,ARHGEF40,ARHGAP26,SAMSN1,TRIM2,PCDHGA10,BEX4,NT5M,ADAMTSL3,NLRP3" Drug 603_UP nifedipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASIC1,MTUS1,PKP4,CHRD,RASL11B,HAP1,CNTFR,CDC42BPB,ARHGEF10,CYBB,C2CD2L,DYNC1I1,SUGP2,MBNL2,MRNIP,CALCRL,EPHB1,CDKL3,ZNF589,FGFR1,TRMO,MCHR1,RNFT2,IL6ST,ITPKB,KIF2A,STMN1,MMP16,MMP17,CNOT4,NTRK3,SETD4,PLCD1,RETREG2,PTPRD,ACSM5,SH3BP2,KIF16B,ZNF430,TMCC1,KIAA0930,VPS35L" Drug 1534_UP Josamycin [16846-24-5]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ALK,AMPD3,AMT,APBB2,PPP4R4,PLA2G4C,MARK4,SYNJ2,BAIAP3,CFAP410,CAMK2B,ARHGEF1,ARHGAP33,TAOK2,HOMER3,HDAC4,GIT2,MFAP3L,STX2,ERBB4,CORO2B,FHL1,AGAP2,SEMA4D,SRCAP,GRIK5,GRM8,DHX35,ICA1,IL6ST,ITPKB,ADAM22,ZNF862,CDK18,ZDHHC14,SYBU,EPN2,FAM214B,RBM34,STX1A,DOCK9,MPPE1" Drug 6321_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "NME5,SHROOM2,KIF1A,ST3GAL5,SCAPER,LDLRAD4,CBFA2T2,CPS1,CRMP1,SUSD5,PDE4DIP,CNTNAP2,TBC1D5,MFAP3L,KIAA0753,MRNIP,STX2,SCARA3,DENND2A,HNMT,KCNN1,MAPT,AFF1,NTRK3,LRRN3,SCN8A,FNDC3A,CCDC88A,SNCA,KDM4B,ZHX3,PHLDB1,SYN2,PCDHGA10,TIAM1,R3HDM1,CABIN1,TRIO,WIPF1,NT5M,UBE3B,PHTF2" Drug 6405_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "NDRG2,APBA2,APC,BCAS1,SEMA4G,ATP1A3,BAIAP3,CFAP410,CAMK2B,USP2,CDO1,ASIC3,SULT4A1,CNN3,SH2B1,VCAN,CNTNAP2,RIMS2,DAPK3,SPOCK3,ERCC2,FAM198B,HPCAL4,CGREF1,RUNDC3A,IFI16,KCNN1,SMAD1,MGAT3,MMP17,MYT1,PURG,SNRK,SNCA,KDM4B,PHLDB1,WSCD1,TCF4,ZEB1,FLRT2,SLC17A7,PLSCR4" Drug 4843_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "AP2A2,FAM131A,PPFIA3,ARHGDIG,GYG2,CA4,CAMK2B,CAMK2G,CACNA2D2,AKAP7,SGSM2,DUSP9,EDNRA,PLXNC1,MTSS1L,ERCC2,SCML2,DLC1,KAT8,ZNF589,KHDRBS3,CSPG5,GNG4,STON1,LPAR4,PCLO,INPP5B,KCNH2,SMAD1,TM6SF1,PDE4B,RETREG1,PPARA,SAMD9,PREX2,CDK5RAP2,KIF13A,CDK19,RUNDC3B,ZNF45,EMSY,TIGD6" Drug 6628_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADRA1D,AMPD2,PDE8B,DNAH17,RIPK1,KIF1A,MYRF,CBFA2T2,PICK1,WHRN,CPS1,HAPLN1,NCOR2,CSNK1E,PDE4DIP,TBC1D5,C2CD2L,EXOG,CDON,EGFR,ZNF589,DENND2A,INPP5K,ZNF276,LPAR4,GPR37,GUCY1B1,SYNPO,MAPT,CNOT4,PIK3R1,STRN3,PRKAR1B,MAPK7,FAM184A,ZNF821,SMARCA4,SS18,WBP2,ZKSCAN5,NDRG4,NAV3" Drug 2963_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APBB2,FAM131A,MADD,SLC4A4,FUBP1,CLOCK,GPRASP1,ZNF337,TBC1D5,SHANK1,ECM2,ZNF549,FHL1,DCTN2,CSPG5,GATM,AP4S1,PADI2,MIA2,AFDN,MPP2,MSR1,NFYA,NNAT,PDE4D,RETREG1,PLCD1,NECAB2,RET,ZFHX4,RXRA,GALNT10,SH3BGR,SEPT8,PDLIM2,ZNF34,CDK20,SMUG1,KCNE5,UGT8,CLIP2,FZD3" Drug 338_DN "azathioprine, USP; Down 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "KDM5D,KIAA1324,LTBP4,SLC2A11,MTMR2,GYG2,CD86,CD38,ARHGEF10,DTNB,VPS13B,ZMYND10,FGFR1,IQCG,KHDRBS3,GABRG2,NEU3,HPGDS,LILRA2,GPR37,NXPH3,HSF2,KCNQ3,STMN1,MBD1,MYO6,MYO7A,NTRK3,FERMT1,PREX2,KBTBD4,SLC12A4,NMNAT2,ZC3H13,SPART,SSTR2,ZC4H2,TACC1,PCDHA5,CDH22,TUBB1,LMF1" Drug 5782_DN Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "C1QTNF1,APBA2,ARNTL,NCOA1,CREM,DZIP3,ARHGAP32,DBT,SGSM2,FAM13A,ING4,STX2,SCARA3,PRRC2B,GUCY1B1,SYNPO,TJAP1,MATN3,ZNF862,CNOT4,MBOAT7,BCAS3,PTPRN2,SH3TC2,FAT4,FBXW7,ZNF671,SBF1,AMBRA1,ST6GAL1,KBTBD4,SMARCD3,LIMCH1,TROVE2,THSD1,SS18,VPS13A,IQCE,UGT8,LMF1,NT5M,KAT6A" Drug 1943_UP Midecamycin [35457-80-8]; Up 200; 5uM; PC3; HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADORA1,ARNTL,N4BP2L1,BMP7,MYRF,SPAG9,CHN2,DPH1,DTNA,EPB41L2,AFF2,INPP5B,NCF2,NOVA1,SLC11A2,FSD1,CYBC1,RET,RGS4,RNASE1,DCUN1D2,ATXN2,FHOD3,ARHGEF40,SLC12A2,ZKSCAN3,KDM4B,DOP1A,STXBP1,SYN2,WSCD1,TCF4,TRIM2,HEY1,TK2,BEX4,CA14,HIRA,PLPPR2,VIPR2,CLIP2,ZNF45" Drug 2075_DN Pindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "KCNAB2,LHX2,VCAN,PPP6R2,GPRASP1,SNPH,FEM1B,EGFR,COQ7,SCML2,SEMA4D,CSPG5,SYT17,ZNF276,GPD2,PCLO,AGFG1,FAM69A,INPP5B,MX1,KCTD15,CNNM2,SAMD9,APTX,PTPN13,MAPK12,SH3BP2,PEX26,BTBD7,COA1,POGZ,FBXW11,SATB2,DICER1,METTL3,HIRA,FAM155A,NPDC1,ZBTB14,TFIP11,HPS4,MPPE1" Drug 4740_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADORA1,SYT13,BEGAIN,TRMT9B,AMPD3,GAS7,SEMA4G,RGS20,PDE8B,DNAH17,ATP2B2,RGS9,PROM1,SCAPER,BAIAP3,AATK,ARHGEF10,MFAP3L,C2CD2L,CDON,RASGRP2,MTSS1L,FGFR1,GAD1,CSDC2,GNAL,GPD1,PCLO,IGF1,KHK,MAPT,ADAM11,MSR1,MTRF1L,CCDC40,CCDC88A,AMACR,TRPM2,SLC30A3,DNALI1,KCNAB1,ITM2C" Drug ctd:C010792 testosterone undecanoate CTD 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ADGRF5,AMPD3,PKP4,AZGP1,PTBP2,CD86,DLGAP2,AHCTF1,CDC42BPB,GREB1,MRO,TMEM35A,IGSF6,KATNAL1,HPCAL4,NSG1,SARAF,RAPGEF6,GLYR1,ZNF638,FERMT2,LINGO1,ELOVL5,MBNL1,PDE1C,TMOD2,PPP2R2C,FAM66C,KLHL11,CPEB3,SLC2A5,BTBD3,SNRPN,FNBP1,DOK5,KLHL4,NACC2,CSMD1,TUBB2A,DOCK8,RTN4,HNRNPA3" Drug 7015_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "NDRG3,CDC42BPA,MADD,NUMB,ZMYM4,SOCS6,CLCN3,QKI,CREM,CTH,GIT2,KIAA0753,MAMLD1,FEM1B,SUGP2,VPS26C,USP21,ATP2C1,CSPG5,TRAF3IP2,GRB10,RNFT2,MAP4,AFF1,OPA1,FSD1,PRKACB,ZSCAN32,SAFB,SUPT20H,KIF16B,SIRT2,ARFGAP1,CDK5RAP2,IFT122,MAPKBP1,TROVE2,CAMTA2,FAM208A,TRIO,UBTF,ZNF189" Drug 6488_UP Bacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APBA2,APOC1,RGS20,MARK4,CALB2,TPP1,STOML1,CNTN1,HDAC4,DGKG,SPOCK2,EGR3,AASS,FGF13,PRELID3A,OGA,DHX35,KIT,LSS,MID1,MMP16,NF1,CNOT4,PALM,PLCD1,MTRF1L,PRPH,RELN,CCDC40,TRIM68,RGS3,SUGCT,FBXW7,KIF13A,ZSWIM8,TRIM2,TRPM2,VIPR2,WIPF1,LAT2,XRCC4,DNALI1" Drug 6475_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "TRMT9B,AMPD3,CDC42BPA,APC,CASK,LDLRAD4,B4GALT6,RAB28,FAM189A2,NRG2,C2CD2L,CNNM1,OPTN,TNK2,EPB41L2,NCALD,EZH1,BAIAP2,FYB1,MALT1,PRRC2B,JAK2,MATK,NELL2,P2RY1,WDR25,PTPRE,RPS6KA2,FUZ,NLGN1,INTS9,LIMCH1,RBM34,THSD1,NXT2,RPGRIP1L,UBTF,CLDND1,KCNK12,REEP1,KCNAB1,TIGD6" Drug 6000_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASPHD1,ADRA1D,ADAM23,CFLAR,LDLRAD4,ARHGAP33,HOMER3,CSF1R,CNTNAP2,DOCK4,DAPK3,GIT2,SGSM2,CNNM1,FGFR1,FHL1,FAM49B,POLL,BTN2A1,MAP4,TAGLN3,PRKAR1B,ZCWPW1,ZNF821,SUPT20H,ASAP3,ABLIM3,BTBD7,CXXC4,IQSEC2,CEP68,PHLDB1,MTCL1,VIPR2,KLC2,ZFP37,ZBTB14,ZNF711,NDRG4,EMSY,SEMA3B,SMIM8" Drug 6030_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "C1QTNF1,SYT13,OGT,PDE8B,MARK4,AZGP1,ADGRB3,KALRN,ASIC3,MFAP3L,SPOCK3,ELN,HSD17B14,NRN1,FGF13,FGFR1,FHL1,ADAM28,PRUNE2,SMAD9,MMP17,TAGLN3,NPY,NOVA1,PDE4A,PLCD1,MINDY2,CEP41,MASP1,GAL3ST4,RGS4,FRMPD1,PKNOX2,SLC11A1,SNCA,ZNF415,ARHGAP26,ATP10B,SYT5,OBSL1,ZFPM2,R3HDM1" Drug 6408_UP valdecoxib; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APC,CDC14B,CACNA1I,CFAP410,ARHGEF1,CNOT8,CRY2,CSF1,B3GAT3,MFAP3L,CHRDL1,EDIL3,MRNIP,DLC1,FGFR1,BAIAP2,TRAF3IP2,DISC1,MSL3,PRRC2B,TDRKH,SHISAL1,KIFC3,MAN2A2,TM6SF1,ZNF862,NF1,NPR2,PLCD1,SAMD9,RGS3,TCP11L1,SBF1,STUM,RASA3,FUZ,SLC4A3,IFT122,VPS13A,COBL,ASTN2,TK2" Drug 5487_UP Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "RALGAPA1,ADCY6,BIN1,KCNAB2,SLC4A4,ALDH7A1,NRP2,MTMR2,BAIAP3,CNN3,CRY2,LYPD1,TMCC2,HSD17B14,VPS13B,ZNF589,ERAP1,RUNDC3A,CNTRL,HNMT,TJAP1,KCNJ5,LSS,GIT1,MSR1,PPP2R2B,PTPRO,ZNF821,SH3GL3,ST6GAL1,DOK5,ZHX3,CLASP2,NSFL1C,ASTN2,SMG6,KIAA0930,RPGRIP1L,CRTC1,LMF1,KCNAB1,MPPE1" Drug 642_UP 6-thioguanine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "KIAA1324,ALK,AQP6,CDK10,ARNTL,RASL11B,ADAM23,AZGP1,C5,CBFA2T2,HINFP,RIMS2,DCAF8,ACOT8,DRP2,DTNA,OLFM1,BAIAP2,HPCAL4,INPP5K,GPR12,GRM8,IL6ST,KCNJ5,MBD1,KITLG,AFF1,MMP17,MYT1,MBOAT7,POLG,PTPRD,RET,ATXN2,ST6GAL1,KBTBD4,EXOC7,TBL1X,SZT2,NDRG4,SEMA3B,MPPE1" Drug 436_UP HA-1077 dihydrochloride; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "ASIC1,KDM5D,BRAP,LTBP4,APC,ARNTL,BMP7,BAIAP3,CAMK2A,CHN2,CNR1,ARHGEF10,SPATA2,ING4,C3orf18,ZMYND10,FCGRT,FGF1,DCTN2,POMT1,FAM49B,SHISAL1,KCNK3,KHK,MEF2C,NNAT,NOVA2,NTRK2,PFKFB4,TMEM104,MTMR10,PTPRN,RNASEL,GSTCD,ASAP3,SLC9A5,SPART,DMXL2,TNS1,VIPR2,MPPE1,AAAS" Drug 6049_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "SEMA6A,AMPH,BIN1,APAF1,GAS7,APOC1,ARHGDIG,MARK4,GYG2,THSD7A,KALRN,CHRNA4,GSDME,CORO2B,HPCAL4,DLL3,GAD1,CACFD1,GRM8,IRF8,ITGA7,KIF5A,SAMD14,NPY,P2RX7,TRHDE,NECAB2,PPARA,RELN,ELOVL2,RGS12,KCTD17,SLC2A5,KANSL3,CCDC88A,LIMCH1,JMJD6,HEY1,LAT2,SLC30A3,SLC17A7,ADAMTSL3" Drug 6293_DN Melatonin [73-31-4]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "MTUS1,C5,HIP1R,SPAG9,ABI3BP,HAPLN1,GIT2,DBN1,SPOCK3,RCAN1,TNK2,FCGRT,POLR1B,EFCAB2,ERAP1,TXNL4A,MSL3,GNG4,MAN1B1,DHX35,MITF,PDE1C,PIK3R1,LRP12,MINDY2,MAPK3,SH3TC2,GAL3ST4,SLC25A36,TCP11L1,SBF1,KDM4D,IFT122,TMCC1,ZBTB43,JMJD6,EXOC7,CABIN1,ZNF142,TFIP11,MAP3K12,PLSCR4" Drug 604_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.78E-05 1.00E+00 9.41E-04 1.06E-02 42 200 "APAF1,APC,ARNTL,N4BP2L1,AZGP1,BAIAP3,CCK,CHN2,HOMER3,CRMP1,DCAF4,DCAF8,GIT2,DBT,JAKMIP2,SUGP2,ING4,GNAO1,GNG4,ATXN2L,KIFC3,PPP2R2B,PPP3CA,PRKAR1B,PRPH,RGS3,RNASE1,TCP11L1,FAM192A,ZNF821,FAM214B,ELMO2,USP33,ZSWIM8,NMNAT2,COBL,EXOC7,TNS2,CRTC1,CHST5,TRIO,WNT7A" Drug 1613_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.81E-05 1.00E+00 9.45E-04 1.06E-02 39 181 "ALCAM,AMT,MAP4K3,DNAH17,SYNJ1,CD86,CD38,ARHGAP33,CHN2,PPP1R16B,DOCK4,TM9SF4,FAM13A,EGR3,ENO2,RASGRP2,IGSF6,VPS26C,PRKAG2,SRCAP,MUM1,GIT1,SMOX,MINDY2,MAPK3,SAMD9,PTK2,PTPRE,USP47,ATXN2,SGK1,SLC6A8,ARHGEF40,MAPKBP1,ZBTB43,THSD1,SLC44A1,TK2,REEP1" Drug CID000447564 Ph-F Stitch 5.93E-05 1.00E+00 9.65E-04 1.09E-02 33 144 "APLP1,ALDH7A1,ATP6V0A1,CA4,CAMK2B,CSNK1E,EBF1,TUBD1,TUBB3,TUBA8,POLL,TNFAIP8L3,MAP2,MAPT,MARK1,NEFM,NEFH,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,KANSL1,RELN,PPP2R3C,SNCA,TTBK2,MCF2L,CABIN1,TUBB2A,TUBB1,UBC,TUBA1A,KAT6A" Drug CID000120739 G 3012 Stitch 6.00E-05 1.00E+00 9.75E-04 1.10E-02 31 132 "KCNH8,UNC5A,SEMA6A,SEMA4G,CHRD,NCOA1,AZGP1,SLIT2,PICK1,PTK2B,SEMA4D,FYN,GAD1,NTNG2,FERMT2,L1CAM,LAMA2,MATK,NCAM2,PLXNB1,RELN,PTK2,ROBO1,ROBO2,FNDC3A,SLA,SLC14A1,UNC5B,TRIO,SEMA3B,RTN4" Drug 7245_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.02E-05 1.00E+00 9.75E-04 1.10E-02 38 175 "ABHD6,ADRB2,MTUS1,EPB41L5,SHROOM2,ARNTL,MARCH3,ST3GAL5,HIP1R,NRXN3,PDE4DIP,CTH,C2CD2L,RGS17,TBC1D16,TAOK3,FGFR1,BAIAP2,FYN,GUCY1B1,FAM69A,KCNN1,PCDH9,SERPINI1,FA2H,PTCH1,PTPN13,RGS4,FBXW7,SH3GL3,ASAP3,WDR47,ELOVL4,CEP68,RGL1,SYT1,TRIM9,DPF3" Drug 990_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "AK2,APC,CDC14B,CFLAR,SYNJ2,CCNT1,B4GALT6,ABCG1,CSNK1E,SOCS5,RUBCN,GPRASP1,DCAF8,GIT2,CELSR3,PHF20L1,EIF5,COQ7,DENND4A,OGA,INPP5K,SRCAP,ZNF276,DIDO1,AGBL5,MAP4,SCAMP5,MBOAT7,PRKACB,TMEM104,ZCWPW1,RGS3,PEX26,UHRF1BP1L,KDM4C,CEP68,TACC1,EXOC7,LMF1,NDRG4,MPPE1" Drug 3989_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ADD2,ALK,PPP4R4,ARHGDIG,NRP2,SYNJ1,CALB2,ARHGAP33,PLEKHB1,TPP1,CNTFR,ABCG1,LRIG1,CSNK1E,SUSD5,ARHGEF4,SNX29,EDNRA,CELSR3,NRN1,DLC1,FAM49B,GNAO1,KCNN3,KIFC3,NPY,ENPP2,PLCD1,DCHS2,CNNM2,BEND5,RGS12,RNASE1,MRAS,ZHX3,PHLDB1,OBSL1,TUBB1,VIPR2,NDRG4,VPS35L" Drug 4319_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "APBB2,SEMA4G,CFLAR,CAMK2B,SCARB1,CACNA2D2,SRSF11,FOXN3,ENTPD4,CRMP1,SPOCK2,SEMA4D,CRCP,POLL,FERMT2,GSTM5,RASSF8,IL6ST,MAP4,NFIX,CNOT4,NTRK2,STRN3,PTN,SLC25A36,KIRREL1,SEC14L1,CCDC88A,ZBTB43,TBCEL,TBL1X,SMG6,TCF4,DICER1,THRA,TMPO,VIPR2,TFIP11,EVI5,KCNAB1,KAT6A" Drug 4575_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "C1QTNF3,TRMT9B,APAF1,ARRB2,BACH1,BMP7,FUBP1,CACNA1G,SEPT7,LARGE1,RAB28,CRY2,CSNK1E,CNTNAP2,ERC2,DTNA,REEP2,FGF1,RUNDC3A,FAM69A,ITGA7,KCNF1,KCNQ3,SMAD1,TAGLN3,MX1,MYT1,NPR2,PALM,CDK18,ZSCAN32,CCDC40,PKNOX2,ZHX3,IZUMO4,COBL,TBCEL,OSBP2,LAT2,KCNK12,SLC17A7" Drug 2238_DN Pindolol [13523-86-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASIC1,NDRG2,APC,EPB41L5,PLA2G4C,MARK4,CFLAR,SYNJ2,GYG2,VAX2,SEC14L5,ZNF589,FGFR1,FHL1,SEPT9,MALT1,POLL,TJAP1,LMO2,MSI1,ADAM22,LYRM9,CCSER2,PRKAR1B,PRPH,ZSCAN2,RNASEL,SH3BGR,PEX26,SMARCD3,SNCA,RBM34,ARHGAP26,PLCB1,EXOC7,KIAA0930,RPGRIP1L,TNS2,TIAM1,TK2,BEX4" Drug 7379_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "NME5,ALK,KCNAB2,SHROOM2,NRP2,CFLAR,CACNA2D1,PLAA,STOML1,AKAP12,MFAP3L,CNNM1,TNK2,ANKFY1,CGREF1,USP19,BACH2,SHISAL1,IL12A,KCNN1,MT1M,NDP,CLDN11,PALM,PDE4D,LRRN3,PRPH,APTX,PTPRH,RGS12,PBRM1,FBXW7,ABLIM3,SMARCC2,SNCA,SAMSN1,PHLDB1,GPR161,CABIN1,VIPR2,EPM2A" Drug 7399_UP Methotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "C1QTNF1,SYT13,AMH,APOC1,CDC14B,SLC4A4,FUBP1,CACNA1I,CACNA1A,WHRN,USP6NL,SPOCK3,EXOG,DRP2,IRAK4,TENM1,ANKMY1,FGF13,FGFR1,BAIAP2,FYB1,GNAL,LMO2,LSS,MATN3,MT1M,NF1,CLDN11,PDE4D,ZSCAN2,ZCWPW1,TRAPPC13,SCN2B,SLA,RBM34,SPTAN1,PHLDB1,KLHL4,RPRM,KCNK12,PLSCR4" Drug 5794_DN Methazolamide [554-57-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "BIN1,APOC1,PDE8B,PLEKHB1,AKAP7,NRG2,SNPH,DAPK3,C2CD2L,FEM1B,MBNL2,RGS17,POMT1,CGREF1,DENND2A,SEPT9,PCDH17,BACH2,INPP5B,JAK2,MAPT,NF1,NLE1,MAPK7,PTPRH,PTPRN2,BEND5,ZDHHC14,KIRREL1,ZNF671,ATXN7,ASAP3,CCDC88A,MCF2L,TIAM1,TK2,UGT8,VIPR2,WIPF1,NDRG4,NAV3" Drug 3384_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ABHD6,NME5,CDC42BPA,APC,EPB41L5,PPP4R4,SCAPER,CBFA2T2,CLGN,STOML1,WHRN,SOCS5,FGFR1,SRCAP,MSL3,CACFD1,ATXN2L,SMAD1,MAP4,LYRM9,PCDH9,PLTP,MINDY2,PPP2R2B,MAPK10,GRAMD1C,ELOVL2,FAM184A,KCTD17,ZFHX4,RPS6KA2,PKNOX2,SMARCD3,KDM4B,CAMTA2,PLCB1,EXOC7,SLC44A1,TPM2,WIPF1,ZFP37" Drug 5791_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "AP2A2,NME5,TRMT9B,RASL11B,BMP7,MYRF,HAP1,RUNX1T1,FOXN3,PICK1,WHRN,AKAP5,RIMS2,SPOCK2,HS3ST2,COQ7,PDLIM5,GPD1,SOX21,ATXN2L,KIT,MAPT,GPR85,PLCD1,PPP2R2B,CNNM2,NKAIN1,ACSS3,RGS4,RGS12,RPS6KA2,KCNIP1,SEMA6D,SNCA,ZBTB43,SSTR2,MCF2L,CRTC1,ZFPM2,BHLHB9,RUNDC3B" Drug 4743_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "FZD9,LTBP4,AMPH,APOC1,LGR5,MARK4,ATP2B2,CA4,HIP1R,NDST3,VAX2,FAM149A,CSF1,ZNF589,AGAP2,FYB1,GAD1,RUNDC3A,GPD1,GSN,SOX21,SETD4,CDK18,PPARA,PTPRB,RASGRF1,TCP11L1,EMID1,SCN2B,SCN8A,FAM214B,KANSL3,PKNOX2,SNCA,ATP10B,ST5,TRIM2,AMACR,VIPR2,KCNK12,DNALI1" Drug 6510_UP Scopoletin [92-61-5]; Up 200; 20.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "RALGAPA1,NDRG2,APBA2,SLC2A11,LDLRAD4,CACNA2D1,TAOK2,LHX2,HOMER3,WHRN,DPP6,DTNA,EGR3,FGFR1,FOXF2,PDLIM5,OGA,SRCAP,GNAO1,HSF2,ICA1,LIG4,MBD1,LRP12,LRRN3,SAMD9,KCTD17,MRAS,SYBU,SLC11A1,SLC14A1,HECW1,UNC5B,ARHGAP26,PHLDB1,STX1A,IQCE,TRIM2,DOCK9,SLC44A1,SEMA3B" Drug 5932_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ABR,LTBP4,ZBTB10,N4BP2L1,SYNJ2,IL33,RAB33A,RAB26,WHRN,ABCG1,VCAN,ING4,STX2,ETV1,OGA,TMEM8B,INPP5K,POLL,STON1,DIDO1,SPACA9,BACH2,HNMT,MT1M,NF1,CNOT4,PRPH,TMEM231,SUPT20H,ASAP3,CDK19,NXT2,CEP68,TAL1,KIAA1107,TNS1,TRIO,WIPF1,HPS4,PLSCR4,RNF170" Drug 7187_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASIC1,ABHD6,AK2,APC,PPP4R4,CFLAR,MTMR3,C5,SRSF11,STOML1,AKAP12,FAM169A,GIT2,JAKMIP2,LYPD1,RCAN1,DTNA,MBNL2,IRAK4,PRELID3A,ERAP1,MAP2,MMP16,MPP2,NF1,SLC11A2,MAPK7,PRODH,DCUN1D2,SYBU,ANKRD6,PPP4R3A,TTC17,ZSWIM8,SS18,NSFL1C,PLCB1,KIAA0930,CLDND1,ZBTB14,MARCH8" Drug 2504_DN Skimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASIC1,APC,ARHGEF7,CAMK2G,ARMC8,CPS1,DCTN1,RHOBTB1,DTNA,IRAK4,TNK2,DENND4A,PCYOX1,SEPT9,ARFIP1,PRRC2B,LILRB4,ACOT7,ITGA7,PAXBP1,NFYA,SLC11A2,PDE4B,RETREG1,DEF8,ZSCAN32,GTDC1,GSTCD,SPATA7,KDM4C,DIP2A,NSFL1C,EXOC7,ZEB1,TK2,LAT2,ZNF32,EVI5,CIAPIN1,EPM2A,NLRP3" Drug 4538_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "CDC42BPA,APAF1,ADAM23,NRP2,SYNJ1,FUBP1,SCARB1,SULT4A1,RAB26,HOMER3,DAPK3,MFAP3L,DMPK,CDON,EDIL3,IRAK4,DLC1,HPCAL4,GRM8,HSF2,IL12A,KHK,LIG4,MMP16,NF1,NOVA2,PDE4A,ENPP2,PLCD1,LRRN3,VPS13C,PTPRH,RASGRF1,KCTD17,FNDC3A,KIF13A,SOX15,GPR161,TK2,TPM2,EVI5" Drug 4626_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASPHD1,ADCY6,N4BP2L1,KSR1,FUBP1,CBS,CHN2,TAOK2,HAPLN1,PDE4DIP,EDNRA,RASGRP2,SPEG,ETV1,PRELID3A,NSG1,FYB1,CYP46A1,AP4S1,BACH2,ELOVL5,IL6ST,KIF2A,MMP16,TAGLN3,CNOT4,PLCB2,FA2H,PPP2R2B,SNRK,TMEM231,PBRM1,NEK11,TCP11L1,EMID1,KDM4B,PHLDB1,KLHL4,FLRT2,EPM2A,DPF3" Drug 3197_DN Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ABHD6,CDC42BPA,PPFIA3,SEMA4G,DNAH17,MARK4,CA12,CAMK2G,KYAT1,SOCS6,PLAA,ARHGEF6,ARHGEF4,CYBB,CELSR3,HSD17B14,KAT8,FGFR1,BAIAP2,FAM49B,ZNF44,TDRKH,GRB10,RNFT2,SLC2A6,HNMT,INPP5B,LMO2,MBD1,NF1,CNNM2,ZNF821,FNDC3A,RBM34,STX1A,EXOC7,SMG6,DOCK9,CHST8,CABIN1,VIPR2" Drug 3539_DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "AP2A2,AMT,CDC42BPA,APC,MARK4,MPDZ,CFLAR,CLGN,SRSF11,WHRN,ABI3BP,MAML1,RUSC2,EDNRA,VPS13B,NCALD,FER,FHL1,FLNC,FAM49B,OGA,GNG4,IL6ST,MAP4,MIA2,LYRM9,NF1,NNAT,NPTX1,PLEC,SEMA6D,SH3BP2,MAPKBP1,CLSTN2,PHLDB1,AP4E1,THRA,PARD3,ZKSCAN5,MAP3K12,ACTR3B" Drug 6621_UP Lysergol [602-85-7]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "C1QTNF1,LTBP4,CAMK2B,RUNX1T1,CRLF1,CSF1R,VCAN,PDE4DIP,CNTNAP2,DAPK3,MFAP3L,EDN3,ZNF391,FLT1,PRELID3A,FYB1,RUNDC3A,GSN,KCNB1,LAMA2,MAPT,AFF1,MX1,MYO7A,NF1,NPY,NOVA2,PCBP3,PCDH9,PDE4B,PGAM2,ZSCAN2,MARCH1,EMID1,SLC11A1,ZHX3,SPTB,SYT5,OBSL1,ICAM5,RIMBP2" Drug 7529_DN Suramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "PKP4,APOC1,BID,RAB28,COL9A3,ENTPD4,NCOR1,NCOR2,MBNL2,MRNIP,CINP,USP19,HTATSF1,GNG4,IL12A,KHK,MMP17,TAGLN3,PALM,PFKFB2,MAPK7,BCAS3,PTPRN2,TMEM231,GAL3ST4,GSTCD,KIF16B,ST6GAL1,DZIP1,SLC4A3,COA1,MYH15,SPTAN1,ARHGEF9,TRIM2,RPGRIP1L,CHST5,HIRA,PDIA2,WNT7A,KCNK12" Drug 2206_DN Finasteride [98319-26-7]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "NDRG2,MTUS1,AMPD3,BIN1,MARK4,SGCE,C5,MYRF,HOMER3,USP6NL,SEC14L5,DBT,SGSM2,FEM1B,RASGRP2,F5,KAT8,EFCAB2,NBEA,SRCAP,GRIK5,GSN,PADI2,LSS,MAP4,SCAMP5,GIT1,NPR2,CEP41,KLK6,TMEM104,TCP11L1,FAM102A,ANKRD6,BTBD7,DOP1A,IZUMO4,ZC4H2,PCDHGA10,CABIN1,URM1" Drug 3321_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASIC1,AP2A2,SEMA6A,CDC42BPA,CFLAR,B4GALT6,TAOK2,CREM,LRIG1,SIPA1L1,CTH,DTNA,MBNL2,VPS13B,EPB41L2,TRMO,GCNT2,RUNDC3A,GLYR1,TDRKH,GPER1,SPACA9,INPP5B,IPO5,GIT1,NEK1,NF1,RETREG1,NLE1,ZSCAN32,ZCWPW1,SYBU,RBM34,KDM4B,KDM4C,STX1A,PLCB1,TRIM2,XRCC4,REEP1,UBE3B" Drug 6516_DN Tiletamine hydrochloride; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.06E-05 1.00E+00 9.75E-04 1.10E-02 41 194 "ASIC1,ABHD6,FAM131A,BCAS1,SLC4A4,CFLAR,CBFA2T2,TAOK2,SIPA1L1,DZIP3,GIT2,DBN1,KIAA0753,CNNM1,EGFR,COQ7,STX2,INPP5K,MALT1,CNTRL,GRIK5,BTN2A1,RNFT2,HNMT,LMO2,MITF,LYRM9,NKAIN1,ZC3H13,ZBTB43,SS18,ASTN2,MTCL1,EXOC7,CHST8,CABIN1,CDK20,HIRA,EMSY,GDPD5,RNF146" Drug CID000026721 etorphine Stitch 6.08E-05 1.00E+00 9.80E-04 1.10E-02 18 59 "ADCY5,ADCY6,ADCY8,ARRB1,ARRB2,CACNA1A,CACNA1B,CACNA2D1,RUNX1T1,KRIT1,CLTC,DNM1,DNM1L,EPHB1,MCHR1,OPRL1,SSTR1,SSTR2" Drug ctd:D012524 Sarin CTD 6.24E-05 1.00E+00 1.00E-03 1.13E-02 55 286 "ACHE,ADD1,ADORA1,ADORA2A,APLP1,DYNLL1,BCHE,CFLAR,MTMR2,CALB2,CALM1,RGN,PLAA,CLCN3,NCOR1,SOCS5,CST3,DBN1,RASGRP2,TUBA1B,TUBB3,GLUL,GNAO1,STMN2,GRIK5,GSTM5,GSTT2,HP,IFI16,LAMP2,MAP2,MAPT,MBP,NACA,NEFH,NRCAM,NTRK2,NTRK3,ABCB1,SERPINI1,PLTP,PMP22,PRKCB,RGS4,ZNF532,S100B,SGK1,SNCA,STXBP1,SYT1,ZEB1,KAT6B,TPM1,AMACR,UBC" Drug 6143_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.33E-05 1.00E+00 1.02E-03 1.15E-02 40 188 "BIN1,ANK2,APBB2,SYNJ2,SGCE,CACNB4,HIP1R,KYAT1,CDH2,CDO1,CHN2,LHX2,PDE4DIP,ZNF337,DUSP9,MAMLD1,FAM13A,ETV1,TLR7,FGFR1,BAIAP2,NSG1,FAM69A,MPP2,NRCAM,SERPINI1,SH3BGR,SNCA,DOP1A,ZC4H2,STXBP1,WSCD1,ZEB1,TRIM2,ICAM5,TPM1,FLRT2,TRIM9,SH3GLB2,ACTR3B" Drug 4386_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.33E-05 1.00E+00 1.02E-03 1.15E-02 40 188 "ASIC1,NDRG2,LTBP4,AMPH,CDC42BPA,APAF1,KCNAB2,CDC14B,RGN,CLGN,TAOK2,WHRN,CSF1,VCAN,ARHGAP24,ELMO1,MBNL2,EGR3,PIPOX,DCTN2,FUT9,NEU3,GPER1,SLC2A6,HMGCR,LSS,GIT1,ZNF493,MRAS,SH3BP2,SH3GL3,ASAP3,SNCA,TRIM2,PCDHGB6,TK2,WIPF1,XRCC4,ITM2C,PARP11" Drug 5116_DN Mometasone furoate [83919-23-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.33E-05 1.00E+00 1.02E-03 1.15E-02 40 188 "ABR,MTUS1,ARRB2,MARK4,RIPK1,SYNJ2,VCAN,SOCS5,SLITRK5,SNPH,ARHGAP24,TMCC2,EDNRA,APH1A,ETV1,GAD1,B4GALNT1,DISC1,SHISAL1,MAPT,NDP,NF1,PPARA,SAMD9,CSRNP3,FAM102A,PEX26,SLC14A1,ZNF415,PHLDB1,TBL1X,TCF4,KIAA0930,ZMAT3,BEX4,PLPPR2,WNT7A,MAP3K12,MPPE1,AAAS" Drug CID000005631 AC1L1KS5 Stitch 6.56E-05 1.00E+00 1.05E-03 1.19E-02 62 334 "ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1B,AGT,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,NFS1,CCK,KRIT1,LRBA,CACNA2D2,PLCXD3,BOC,DBI,SNAP91,EDN1,EDN3,EDNRA,EDNRB,PPP1R1B,ATP2C1,PLCD4,GRM2,GRM8,SCIN,KCNK3,KITLG,NPY,OPRL1,OXTR,P2RY1,PIK3C2A,PIK3R1,PKD1,PLCB2,PLCD1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PSD,PTH1R,RYR3,MAPK12,SLC2A5,SLC14A1,PLCB1,SYT1,AKTIP,TIAM1,VIPR2,PLD4" Drug 1755_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 6.59E-05 1.00E+00 1.06E-03 1.19E-02 39 182 "ADORA1,ARRB2,CFLAR,CBR1,CD86,CD38,MAP4K4,CNTFR,AKAP7,CREM,SH2B1,AATK,SIPA1L1,DOCK4,ARHGAP32,BAIAP2,NSG1,CACFD1,PACSIN2,KIFC3,LAMP2,NACA,PALM,PDE4B,SMOX,QDPR,MRPS18A,SATB1,FUZ,FNBP1,SAMSN1,THSD1,CEP68,PLCB1,SSBP2,FLRT2,NPDC1,MPPE1,ST7" Drug 6104_UP Propidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,C1QTNF3,RGS20,ADGRB1,NRP2,GYG2,CA4,CHRNA4,CNTNAP2,RASSF2,EXOG,EDN1,TNK2,SPEG,PIPOX,ZNF44,RUNDC3A,ADAMTS13,C2orf72,KCNH2,AFDN,MYT1,NF1,NOVA2,P2RX7,TREM2,PDE4D,PGAM2,DUSP26,RETREG1,GDPD2,RGS12,CLIP1,SH3BP2,CDK19,DNAH7,R3HDM1,TRIO,TUBB1,ITM2C,JPH3" Drug 5569_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ADD2,AGT,AMPD3,APBA2,KCNAB2,MARK4,LDLRAD4,CFAP410,HAP1,CAMK2B,KYAT1,CBFA2T2,KCNAB3,STOML1,NRG2,MFAP3L,REEP2,OLFM1,AFF2,FOLR2,EFCAB2,GLYR1,GRM8,IL6R,INPP5B,KHK,NF1,P2RY1,GPR85,PNMA3,LRP12,ELOVL2,NKAIN1,SLC8A1,ZNF415,SPART,ATP10B,SYN2,WIPF1,XRCC4,ITM2C" Drug 4467_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "BEGAIN,APAF1,BCHE,NRP2,CFLAR,KSR1,IL33,CA12,ABCG2,HOMER3,DGKG,SPOCK2,GIT2,CHRDL1,CDON,TNK2,ST3GAL6,SIGLEC8,PCDH17,GLYR1,MSL3,STON1,GPER1,CACFD1,NXPH3,LAMA2,ADAM22,CEP41,PTN,PTPRN2,SH3TC2,PNMA8A,KCNIP1,ARHGEF40,SLC11A1,HECW1,ATP10B,ADGRL3,TPM2,ZNF225,KCNAB1" Drug 4263_UP Primaquine diphosphate [63-45-6]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "BBOX1,PPP4R4,SYNJ2,LDLRAD4,RUNX1T1,NDST3,AKAP6,CSF1,BRINP1,DRP2,EDN3,ERBB4,HPCAL4,EFCAB2,PDLIM5,SIGLEC8,GFER,CSDC2,FAM107A,LSAMP,ADAM22,MYT1,NELL2,NTRK3,P2RX7,RETREG1,NECAB2,MARCH1,C1orf54,RASGRF1,KHDRBS2,RGS4,RYR3,SLC6A11,IZUMO4,ZBTB43,TK2,TPM2,WIPF1,KCNK12,NLRP3" Drug 3774_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "MTUS1,ALDH7A1,NRP2,SYNJ2,ARHGEF7,CFAP410,CBS,CHN2,B4GALT6,LY86,AKAP5,ABI3BP,VCAN,CNTNAP2,SLITRK5,DAPK3,EXOG,FCF1,EGFR,ETV1,ANKFY1,PDLIM5,SEPT9,PRRC2B,ELOVL5,HNMT,SCIN,STRN3,PRPH,SNRK,ZSCAN32,ENOX1,NEK11,SLC9A5,ZNF415,PEG10,CEP68,KIAA1107,TNS1,REEP1,PHTF2" Drug 7254_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "AMPD3,APC,APOC1,SLC4A4,CFLAR,RUNX1T1,SOCS6,LHX2,NRXN3,DZIP3,SNPH,DBT,MFAP3L,CELSR3,EGFR,RGS17,BAIAP2,SCIN,FAM69A,ADAM22,NEK1,MBOAT7,MAPK7,MRAS,LIMCH1,TSNAXIP1,ZHX3,KDM4C,ZBTB43,SS18,DIP2A,SYT1,ADGRL3,TNS1,PIK3R5,SSBP2,VIPR2,WIPF1,NT5M,NAV3,KCNAB1" Drug 4369_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASIC1,DOC2A,DNAH17,GYG2,BAIAP3,CFAP410,HAP1,SLIT2,LHX2,STOML1,PICK1,WHRN,CRY2,ABCG1,DBN1,STX2,KAT8,OLFM1,DISC1,PCDH17,RUNDC3A,STON1,HNMT,TJAP1,KCNH2,KHK,KIFC3,MID1,NNAT,ELOVL2,RIPOR1,TRIM68,ZFHX4,TCP11L1,RASA3,ASAP3,SNCA,CLSTN2,VPS13A,CRTC1,FLRT2" Drug 2163_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASIC1,MTUS1,AMPD3,MARK4,ADAM23,LDLRAD4,CCNT1,TAOK2,CNTN1,KIAA0586,DBN1,DTNB,CNNM1,ING4,RASGRP2,CDKL3,F5,FLT1,OGA,ZNF44,SEPT9,POLL,KCNJ5,MX1,NF1,TREM2,PFKFB2,CCSER2,PMP22,PPARA,SH3BGR,SLC11A1,DOK5,IZUMO4,STX1A,TCF4,PARD3,CABIN1,TPM1,FLRT2,KAT6A" Drug 6255_DN Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASPHD1,MTUS1,CDK10,BMP7,CHN1,CNOT8,TMEM184B,GIT2,RHOBTB1,DNM1,NR1D2,ERBB2,CINP,SYT17,SRCAP,COPS8,ICA1,FAM69A,NCAM2,CNOT4,CCSER2,SMIM7,FSD1,PTK2,RIPOR1,TMEM231,MSANTD2,CCDC25,MCMBP,SAFB,KBTBD4,SMARCC2,TMCC1,POGZ,NXT2,ANKRD12,TRIM2,CLASP1,TIAM1,RPRM,RNF146" Drug 2245_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,LTBP4,AMPD3,BIN1,CDC42BPA,RGS20,PLA2G4C,MARK4,CACNA1A,CBFA2T2,LHX2,WHRN,SH2B1,CSF1R,PDE4DIP,MFAP3L,CDON,EIF4G2,FHL1,GCNT2,POLL,GPER1,CNTRL,INPP5B,KCNF1,MSI1,ADAM22,NTRK2,PRODH,ZCWPW1,TRIM68,RGS12,TCP11L1,SBF1,CNKSR2,WSCD1,SLC44A1,WIPF1,GDPD5,HPS4,KAT6A" Drug 2396_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,ADGRF5,APAF1,PPFIA3,ARRB2,ZSCAN18,MTMR3,CDH2,CPNE6,HOMER3,PICK1,ENTPD4,CRMP1,CTH,DCAF4,GSDME,DLC1,AFF2,EFCAB2,ZNF44,SEPT9,INPP5K,POLL,ICA1,KCNJ5,LAMA2,CLDN11,LRRN3,MAPK10,KCNIP1,SEC14L1,SLC11A1,SNAP25,IQSEC2,TROVE2,FAM189A1,TK2,SSBP2,LAT2,KCNAB1,PHTF2" Drug 3835_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ADRA1D,APBB2,GAS7,BCAS1,ARNTL,CFLAR,SCAPER,TAOK2,CSF1,PDE4DIP,GPRASP1,DAPK3,FCF1,EIF4G1,ELN,HSD17B14,ZNF589,INPP5K,GLYR1,KITLG,ADAM22,ZNF862,NEK1,NF1,NPR2,RETREG1,PLXNB1,ZSCAN2,RGS12,EMID1,SBF1,SEC14L1,SLC6A8,SMARCD3,SNCA,ZBTB43,NXT2,PLCB1,TBL1X,TRIO,MAP3K12" Drug 6135_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ADCY6,DOC2A,BIN1,CDC42BPA,FGD2,BCAS1,KIF1A,BCL7A,LDLRAD4,CACNB4,HAP1,RUNX1T1,CD38,CDH2,CDO1,DGKG,CNNM1,OPTN,AGAP2,PDLIM5,CAMKK2,CPLX2,SCIN,KCNJ5,MMP17,TAGLN3,VPS13C,PTCH1,RFX2,ST6GAL1,SMARCD3,TMCC1,KDM4B,IZUMO4,HECW1,PHF24,TPM1,AMACR,SLC17A7,KCNAB1,TIGD6" Drug 4657_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ATP2B2,ADAM23,ADGRB2,BMP7,USP2,SLC16A4,CHN2,CHRNA4,RGS6,SUSD5,SV2B,DRP2,DTNB,APC2,ERGIC3,FYB1,ALDH1L1,GLI2,SPACA9,FICD,KIT,MT1M,MYCN,NF1,NOVA1,PDE4D,GRAMD1C,CNNM2,PTPRH,C1orf54,ZMAT4,RFX2,PKNOX2,CXXC4,ZHX3,ATP10B,SLC44A1,TLR4,EPM2A,HRASLS,ST8SIA2" Drug 1318_UP Metrizamide [31112-62-6]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "DNAH17,STX16,ATP2A2,SYNJ1,CBR1,CLGN,SMARCAL1,BAG4,RNF14,ZFYVE16,DBT,GSDME,RCAN1,HIPK3,FCF1,CELSR3,EPB41L2,PTK2B,ZNF589,CELF1,GALC,ARFIP1,HSF2,KPNA5,MAP4,NFYA,SLC11A2,PLEC,ZNF671,RASA3,PPM1E,IZUMO4,KDM4C,SS18,NXT2,PLCB1,TBCEL,TMPO,KAT6B,TSN,SLC17A7" Drug 4155_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASIC1,ADORA1,AP2A2,NME5,APBB2,APOC1,CFAP410,CA4,CAMK2G,SLIT2,CRY2,PPP6R2,TMCC2,HIPK3,SUGP2,PLXNC1,ING4,VPS13B,ZNF589,TRAF3IP2,SEPT9,GCNT2,GPER1,KCNH2,KIT,MMP16,NF1,PLCD1,MINDY2,PRKAR1B,RGS12,DCUN1D2,TCP11L1,SH3BP2,KIF13A,DOK5,CRTC1,TRPM2,VIPR2,KCNAB1,PLSCR4" Drug 3737_DN Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ALK,CDC14B,ADGRB2,C5,SYNGR3,ARHGAP22,HOMER3,CNTN1,NCOR2,ABCG1,AATK,MAML1,DTNA,APH1A,FGF1,FGFR1,CINP,PDLIM5,CGREF1,FERMT2,KCNJ5,PDE4B,PDPK1,POLG,CEP41,PID1,KIRREL1,RPS6KA2,ZNF821,ASAP3,DZIP1,BTBD7,SPTAN1,MCF2L,SYNE1,TPM2,HIRA,RPRM,PLPPR2,SEMA3B,DPF3" Drug 2741_DN Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ABHD6,MTUS1,PKP4,PPP4R4,ARRB1,SYNJ1,FUBP1,SLC16A4,SCARB1,FOXN3,EPS15L1,CREM,CSF1,DZIP3,USP6NL,HDAC9,DAPK3,E2F5,NCALD,RRAGB,KAT8,ZNF589,FGFR1,FHL1,NBEA,DISC1,LILRA2,IL6ST,MEF2C,NNAT,CCSER2,POU6F1,MINDY2,PTCH1,RIPOR1,RGS3,STX1A,ADGRL3,KIAA1107,TCF4,CRTC1" Drug 5313_DN Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ARRB2,NCOR1,FAM169A,RUBCN,USP6NL,DCTN1,DNM1,APH1A,PLEKHA1,EZH1,FGFR3,ANKFY1,CGREF1,B4GALNT1,BTN2A1,IL6ST,MEIS2,MIA2,OGG1,OPA1,PCDH9,RETREG1,SMIM7,POLG,CNNM2,TMEM231,ROBO1,SMARCA4,TMCC1,KDM4B,ZSWIM8,ZBTB43,ARHGEF9,TIAM1,BEX4,TP53BP1,HIRA,VGF,ZNF32,MPPE1,EPM2A" Drug 1628_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "KCNAB2,ARHGDIG,SLC4A4,ADAM23,CFLAR,SYNJ2,GYG2,CAST,MAGI1,SH2B1,NCOR1,PDE4DIP,ARHGEF4,MBNL2,PLEKHA1,BAIAP2,FHL1,TXNL4A,HNMT,INPP5B,ADAM22,PLCD1,SLC25A23,CARF,CCDC25,ZC3H14,TCP11L1,RPS6KA2,ZNF821,TRA2B,KIF16B,KDM4C,KIAA1107,CHST8,VGF,VLDLR,WIPF1,SPHK2,MAP3K12,EMSY,MPPE1" Drug 5980_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NME5,AK2,BIN1,PDE8B,CACNA1I,LDLRAD4,CD86,ARHGAP33,CBARP,TAOK2,NRXN3,NRG2,CSNK1E,CNTNAP2,DTNA,SEMA3D,RABEPK,NCALD,DLC1,BAIAP2,ERAP1,SIGLEC8,DISC1,HSF2,KIF2A,MSI1,PFKFB2,RETREG1,RGS4,GSTCD,PPP4R3A,IZUMO4,SPTAN1,SYT1,MCF2L,GPR161,VGF,ZNF711,NAV3,SLC17A7,DPF3" Drug 4402_DN Tiabendazole [148-79-8]; Down 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NME5,PLA2G4C,MPDZ,CA4,CAMK2G,SCARB1,SOCS6,SIPA1L1,MFAP3L,DMPK,DTNA,FGF13,OGA,SRCAP,TXNL4A,KPNA5,MAPT,ADAM22,CNOT4,CNNM2,ZDHHC14,GTDC1,RGS12,TCP11L1,ASAP3,WDR47,BTBD7,SLC22A4,LIMCH1,RBM34,KDM4C,ARC,DMXL2,PCDHA6,HIRA,FLRT2,EMSY,GDPD5,ST7,KAT6A,RNF170" Drug 5582_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "SYN3,NDRG2,N4BP2L1,RGS11,CBFA2T2,ARHGEF2,CACNA2D2,SULT4A1,ARHGEF4,MYEF2,RUSC2,MBNL2,PLXNC1,VPS13B,MTSS1L,IGSF6,SPEG,CAMKK2,GAD1,GLYR1,GNAL,NXPH3,ADAM22,MSR1,MYO7A,NOVA1,NTRK2,PCDH9,PLCB2,ZNF493,BEND5,EMID1,SH3BP2,CNKSR2,IZUMO4,ATP10B,DOCK9,HIF3A,GPR161,R3HDM1,KCNAB1" Drug 2861_UP Piracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASIC1,ADRA1D,NME5,ALCAM,BIN1,APAF1,APOC1,PPFIA3,CDC14B,ADAM23,GYG2,BAIAP3,CAMK2A,HIP1R,ARHGAP33,RASSF2,MFAP3L,DUSP9,HSD17B14,ERCC2,NCALD,GPER1,GRIK5,BACH2,ICA1,KIF5A,NPTX1,TMOD2,SMOX,RIPOR1,TRIM68,EMID1,RASA3,SH3BP2,ASAP3,SNCA,CLSTN2,ST5,SMG6,CABIN1,VLDLR" Drug 5305_UP Cisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASPHD1,AP2A2,CDK13,KIF1A,BMP7,C5,CFAP410,HIP1R,SYNGR3,RAB26,CSNK1E,PDE4DIP,GREB1,GIT2,PARD6A,MED12,DTNA,OPTN,FECH,BAIAP2,FHL1,PRELID3A,POLL,SLC2A6,KCNN1,MAP4,NF1,OGG1,SLC25A23,ZCWPW1,TCP11L1,KCNIP1,SYBU,EPN2,FAM214B,BTBD7,ARHGAP26,EXOC7,TMEM121,KLC2,HPS4" Drug 3806_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ASPHD1,AP2A2,SEMA7A,PKP4,PPP4R4,RASL11B,ATP1A3,BMP7,ABI3BP,CRMP1,RIMS2,ING4,FGF1,FYB1,GNG4,GPD2,ATXN2L,KIT,MAPT,LYRM9,NLE1,STRN3,MAPK7,PRPH,CNNM2,PTPRB,ACSS3,SUPT20H,RASA3,ASAP3,ST6GAL1,NLGN1,ZNF334,OGDHL,SNCA,DOK5,ZHX3,UNC5B,SPTAN1,LHPP,IQCE" Drug 4393_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "SRPX,BIN1,CFAP410,ARHGAP33,QKI,PUM1,EXOG,SLC12A6,MBNL2,ERBB2,FHL1,FAM49B,GAD1,SYT17,PCLO,CACFD1,TJAP1,INPP5B,KPNA5,LMO2,NF1,SLC11A2,SMIM7,STRN3,LRP12,PTCH1,CEP97,RGS12,CCDC25,ASAP3,FNDC3A,IQSEC2,SYNE2,PLCB1,ARC,TACC1,DMXL2,TRIM2,HIRA,LMF1,ZNF24" Drug 7394_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "PDE8B,SLC4A4,CFLAR,CAMK2A,DLGAP2,FOXN3,ARHGEF10,PDE4DIP,SPOCK3,DRP2,DTNB,ETV1,FGF13,FYB1,ERAP1,ELOVL5,KIFC3,MGAT3,MT1M,NF1,CLDN11,DUSP26,FA2H,PPARA,PPP5C,BCAS3,PTPRN2,ENOX1,ZDHHC14,TRAPPC13,FRMPD1,DZIP1,SLC2A5,RBM34,SPTAN1,IQSEC2,ADGRL3,ZNF34,VIPR2,XRCC4,SENP7" Drug 3757_UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,APBB2,DNAH17,ATP2B2,BMP7,GYG2,CAMK2B,AKAP6,CABP1,NCOR2,LRIG1,ERC2,MRNIP,PDLIM5,GNAL,PADI2,IGF1,KCNB1,KCND2,LAMA2,MARK1,MATK,MMP17,ADAM22,NPTX2,PCSK1,DCHS2,RNASEL,S100B,STUM,RASA3,CPEB3,PREX2,LIMCH1,KIF13A,MCF2L,R3HDM1,TRO,TUBB1,UBE3A,ZNF24" Drug 1330_DN Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "C1QTNF3,CDC42BPA,APAF1,APBB2,CFLAR,MTMR2,LDLRAD4,CACNA1A,CAPN3,KYAT1,TPP1,RUBCN,DTNA,FEM1B,SUGP2,EIF1,GPHN,ARFIP1,AHDC1,LILRA2,MAP4K5,HSF2,TJAP1,IL6R,MIA2,SLC11A2,PDE4B,CCSER2,TMEM231,ZNF671,FAM102A,NXT2,CEP68,NSFL1C,TPM1,SSBP2,ZNF142,FTSJ1,EMSY,NT5M,MPPE1" Drug 3191_DN Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ADCY6,AP2A2,LTBP4,FAM131A,PPFIA3,CFLAR,TAOK2,DZIP3,ZNF337,MAMLD1,EDNRA,FGFR1,BAIAP2,PRKAG2,SEMA4D,CGREF1,COPS8,ITPKB,KHK,MAP4,LYRM9,CCSER2,RETREG1,PRKACB,PRKAR1B,PTPRE,FBXW7,SMARCC2,KIF13A,ZHX3,CLASP2,TACC1,FBXW11,CRTC1,ZNF34,KAT6B,ZKSCAN5,HIRA,ZNF74,EMSY,UBE3B" Drug 7539_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NME5,AMPD3,EPB41L5,SLC4A4,CFLAR,CACNA1I,BAIAP3,CBFA2T2,AP4M1,VCAN,DGKB,EXOG,TNK2,LRRC17,STX2,ZNF391,FLT1,GPD2,L1CAM,NF1,NOVA2,SETD4,POLG,CEP41,CNTLN,TMEM231,RGS4,GSTCD,SUPT20H,SLC9A5,ZNF667,TSNAXIP1,IQSEC2,COBL,TBL1X,UGT8,LMF1,ZBTB14,ZNF74,TFIP11,SEMA3B" Drug 5117_DN Bumetanide [28395-03-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ACTN1,ADCY6,APC,MARK4,ADGRB2,SYNJ2,FUBP1,SCARB1,LARGE1,HAPLN1,ARHGEF10,ARHGAP32,DAPK3,DCTN1,ERBB2,ETV1,SEMA4D,SEPT9,MSL3,POLL,SHISAL1,MAPT,MIA2,CNNM2,RIPOR1,MAP6D1,ZFP30,EPN2,SMARCA4,FNBP1,ZBTB43,TBL1X,WSCD1,OBSL1,CBX5,HIRA,UBTF,VGF,EVI5,SEMA3B,SLC17A7" Drug 5941_UP H-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "AP2A2,NME5,LTBP4,ALK,AMT,GAS7,APOC1,BCAS1,CFAP410,ARHGAP33,CLTB,RASGRP2,CELF1,OGA,ERAP1,DISC1,GATM,ALDH1L1,TXNL4A,GLYR1,GNAL,LPAR4,SPACA9,ELOVL5,MAPT,MATN3,NEK1,NF1,SLC25A23,FSD1,ZCWPW1,GAL3ST4,TCP11L1,SH3BP2,PEX26,DDN,PLCB1,TK2,VIPR2,SLC17A7,KCNAB1" Drug 3458_DN Ebselen [60940-34-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ABHD6,NDRG3,APBB2,BCAS1,ADAM15,MPDZ,B4GALT6,CNOT8,QKI,PDE4DIP,FAM169A,DCAF8,DBT,MFAP3L,RCAN1,TNK2,ZNF589,CGREF1,GHR,DHX35,LIG4,MAP4,MBD1,KITLG,MMP16,RETREG1,RETREG2,PRKAR1B,APTX,ELOVL2,ZSCAN32,SIRT2,CDK19,THSD1,TACC1,EXOC7,TIAM1,TMPO,BEX4,PLPPR2,MPPE1" Drug 3941_DN Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,AP2A2,DOC2A,APBA2,APLP1,CDK10,ARHGDIG,CDK13,BCL7A,LDLRAD4,CA4,CBFA2T2,CLTB,MAML1,PARD6A,DNM1,CDON,EDNRA,RASGRP2,PIPOX,EZH1,FHL1,KHDRBS3,DLL3,SRCAP,USP19,CNTRL,MSR1,ZNF862,NPY,CLDN11,PLXNB1,MAPK7,PTN,SH3BP2,ST5,ARC,CABIN1,HIRA,LAT2,SPHK2" Drug 6769_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "LTBP4,KCNAB2,DNAH17,RASL11B,CA4,ARHGEF1,NECTIN3,DAPK3,ZNF804A,SGSM2,DMPK,FHL1,SCARA3,PDLIM5,USP19,COPS8,TDRKH,ICA1,ITPKB,ADAM22,TAGLN3,ZNF862,NF1,NLE1,PLCB2,PLXNB1,MBOAT7,PPARA,ZSCAN2,RGS12,SBF1,ARFGAP1,ZSWIM8,SPTB,IQSEC2,RBM26,PLCB1,GPR161,ZNF34,KCNK12,EPM2A" Drug 3163_DN Glibenclamide [10238-21-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ABHD6,PPFIA3,BCL7A,CAMK2G,SOCS6,FAM189A2,HOMER3,AKAP7,CRY2,TOM1,CNNM1,EIF5,VPS26C,ANKFY1,FYN,SYT17,MALT1,POLL,FERMT2,TDRKH,GRB10,INPP5B,MATK,MIA2,NF1,CNOT4,RGS3,RPS6KA2,SBF1,SGK1,EPN2,BTBD7,EXOC7,CRTC1,PCDHA6,TMEM121,ZNF34,HIRA,LMF1,REEP1,MPPE1" Drug 7451_DN Triflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "ABR,AK2,PKP4,CAMK2G,SPAG9,CBFA2T2,FOXN3,ZFYVE16,C2CD2L,MAMLD1,FEM1B,CELSR3,SUGP2,BAIAP2,B4GALNT1,SEPT9,AHDC1,BTN2A1,FAM69A,MBD1,NCAM2,NEK1,NF1,CNNM2,RIPOR1,FUZ,PEX26,EPN2,CDK5RAP2,MAPKBP1,KDM4B,SOX3,SPTAN1,LHPP,HIRA,UBTF,LMF1,XRCC4,EMSY,GDPD5,ACTR3B" Drug 6159_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "NDRG2,C1QTNF3,ALK,CDC42BPA,AQP6,CDK10,ATP6V0A1,ADGRB1,MPDZ,MTMR3,LDLRAD4,HAP1,RUNX1T1,CBFA2T2,CREM,SPOCK2,E2F5,EGR3,SRPK3,RASGRP2,MTSS1L,ERCC2,FHL1,FLT1,SCIN,KCNN1,MSI1,NPY,NRCAM,MAPK10,BCAS3,CRTAC1,FRMPD1,CXXC4,KDM4B,MCF2L,WSCD1,TRIM9,SLC17A7,KCNAB1,PCBP4" Drug 6738_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.84E-05 1.00E+00 1.08E-03 1.22E-02 41 195 "APC,ARRB1,ADGRB2,SCAPER,IL33,CFAP410,CA4,HAP1,ARHGAP33,RGS6,SPOCK3,EDIL3,HIPK3,TENM1,ING4,ETV1,FGFR1,ERGIC3,NSG1,RUNDC3A,TOX3,PRUNE2,ELOVL5,PACRG,ADAM11,KITLG,ADAM22,NF1,PFKFB2,PPP1R1A,PPP5C,ZMAT4,ZFP30,SLC2A5,ZNF334,ATP10B,ARC,EXOC7,SZT2,DOCK9,GPR161" Drug 6736_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.10E-05 1.00E+00 1.12E-03 1.27E-02 37 170 "ADRB2,NME5,APAF1,EPB41L5,ARNTL,ST3GAL5,HIP1R,USP2,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,BAIAP2,OGA,FYN,GUCY1B1,BACH2,FAM69A,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,ENOX1,RGS4,SH3GL3,CPEB3,DOP1A,THSD1,ELOVL4,RGL1,SYT1,COBL,SLC17A7,PLSCR4" Drug 922_UP celecoxib; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.16E-05 1.00E+00 1.13E-03 1.28E-02 40 189 "NDRG2,APC,ATP2B2,BCL7A,ST3GAL5,CHRNA4,B4GALT6,ABI3BP,RCHY1,PDE4DIP,DZIP3,ARHGEF4,DBT,SPOCK3,DTNA,EDNRA,ST3GAL6,ZNF589,ERAP1,SIGLEC8,RASSF8,DHX35,MGAT3,NF1,NNAT,NPTX1,PLTP,PTPRB,PPM1E,ASAP3,EPN2,KANSL3,SLC22A4,SOX3,CAMTA2,ZNF34,TRIO,RUNDC3B,VIPR2,REEP1" Drug 4688_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.16E-05 1.00E+00 1.13E-03 1.28E-02 40 189 "NME5,SRPX,AMPH,GAS7,KSR1,SCAPER,CACNA2D2,RCBTB2,TPP1,PDE4DIP,CTH,DAPK3,EIF4G2,ING4,BAIAP2,KHDRBS3,ERAP1,TDRKH,PCLO,LMO2,MAP2,AFF1,CNOT4,PDE4B,SERPINI1,PLCD1,SLC25A23,SMIM7,PTH1R,C1orf54,TCP11L1,SMARCD3,ZNF415,CLSTN2,SAMSN1,CEP68,PLCB1,CHST8,TUBB1,SLC30A3" Drug 2405_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.16E-05 1.00E+00 1.13E-03 1.28E-02 40 189 "CDC42BPA,APAF1,DNAH17,CARS,CDO1,CHRNA4,TPP1,HAPLN1,PPP1R16B,CTH,DBT,MFAP3L,DTNA,PLXNC1,F8,FYN,PCLO,GRM8,AP4S1,ATXN2L,ICA1,IFI16,ZNF862,OCRL,RETREG1,PPARA,MAPK7,RGS3,RPS6KA2,RTN1,ZFP2,SEC14L1,CNKSR2,EPN2,FAM214B,TSPYL2,PDLIM2,FLRT2,MAP3K12,SENP7" Drug CID000004362 N-ethylmaleimide Stitch 7.29E-05 1.00E+00 1.15E-03 1.30E-02 87 511 "SYN3,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,AP2A1,MYH7B,MAGEE2,SPTBN4,STX16,ATP2A2,ATP2B2,KIF1A,CALM1,RGN,CD38,ENTPD2,MYL6B,CLTC,DNM1,SLC12A6,DTNA,DTNB,EGFR,ELN,SLC43A2,STX2,ERBB4,POLK,VTI1B,SYNCRIP,ATP2C1,GAD1,DISC1,CPLX2,GHR,GLUL,GRIA2,GSTM5,GSTT2,IDH3A,IDH3B,KCNB1,KIF2A,KIF5A,KIFC3,SYTL4,MAT2A,AFDN,MYH3,MYO5A,MYO6,MYO9A,NBL1,OPRL1,CNTN3,PDE4B,ABCB1,POLG,REV3L,FIGN,KIF7,STX1B,KIF27,KIF21A,KIF16B,MYO18A,FNDC3A,SLC12A4,NAPB,SNAP25,KIF13A,SPTAN1,STX1A,STXBP1,NSFL1C,SYN1,SYN2,SYP,SYT1,SYT5,SMG6,AKTIP,ACTR6,STXBP4,GORASP1" Drug 5599_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.48E-05 1.00E+00 1.18E-03 1.33E-02 39 183 "RALGAPA1,SEMA6A,APAF1,APBA2,APOC1,N4BP2L1,SCAPER,RUNX1T1,CHN2,CSF1R,EDNRA,ING4,EPHB1,F5,OLFM1,CAMKK2,GLYR1,STON1,PCLO,GRIK5,ICA1,KCNJ5,LMO2,MAP2,LYRM9,ZNF862,CNOT4,SERPINI1,LRP12,PTPRB,CARF,KANSL3,SNCA,KDM3A,CDK19,ATP10B,CEP68,RGL1,UBE2H" Drug 6910_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.48E-05 1.00E+00 1.18E-03 1.33E-02 39 183 "NME5,MARK4,BMP7,BAIAP3,WHRN,COL4A5,PREPL,PDE4DIP,ARMCX2,OPTN,EPB41L2,STX2,BAIAP2,NBEA,FYN,CYP46A1,RAB40B,STON1,MXI1,NEK1,PDE4A,SERPINI1,PKIA,PRPH,SH3BGR,SH3GL3,WDR47,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,HEY1,BEX4,NPL,RUNDC3B,SSBP2,SLC17A7,ITM2C" Drug 7084_UP MS-275; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.48E-05 1.00E+00 1.18E-03 1.33E-02 39 183 "ABHD6,ADGRF5,ARNTL,ST3GAL5,IL33,ABCG1,VCAN,CNTNAP2,DOCK4,PLPPR4,EDNRA,RGS17,FGF1,FGF13,FYB1,GRB10,GUCY1B1,BACH2,MAP2,MEF2C,MMP16,TAGLN3,PDE4B,ENPP2,RETREG1,PMP22,RGS4,ST6GAL1,SYBU,THSD1,CEP68,RGL1,SYT1,COBL,XRCC4,TRIM9,SEMA3B,NAV3,PLSCR4" Drug ctd:C016599 mono-(2-ethylhexyl)phthalate CTD 7.56E-05 1.00E+00 1.19E-03 1.34E-02 107 657 "KDM5D,GALNT13,ADORA1,ADRA1D,MTUS1,HECW2,HACE1,NME5,AMH,ZFAT,LGR5,SEMA4G,SPTBN4,ARRB2,CHRD,NCOA1,ATP1A3,ADAM23,CFLAR,DST,KALRN,CBS,MTMR7,SCARB1,KCNAB3,LRRFIP1,CDO1,HOMER3,CABP1,CRHBP,NCOR1,RGS6,LRIG1,RASGEF1C,CTH,DGKB,DMD,DPP6,EDN1,SEMA3D,EGR3,ERBB4,NRN1,FAM198B,ZNF461,ACSL4,PTK2B,SCARA3,ATP13A4,SPECC1,ATP6V1H,BRSK1,IQGAP2,PPARGC1A,DHRS4,TOX3,AIFM3,CNTRL,BVES,HAS2,FRMD5,HMGCR,KNDC1,KCNJ16,TTYH2,NCOA7,MAPT,MBP,ADAM22,MYCN,MYO7A,NEK1,NRCAM,OXTR,CNTN3,PDE4D,NALCN,PLCB2,PLIN1,PDZRN4,PPARA,PPP1R1A,MAPK3,EPDR1,PRPH,PTCH1,PTPRD,PTPRH,TMEM145,SLC25A48,ENOX1,RASGRF2,ATP8B4,RXRA,KIF27,SGK1,SH3BGR,FAIM2,LHPP,CLASP2,SSTR1,PDLIM2,RIMBP2,TPM1,STXBP4,VLDLR,WNK2" Drug 2440_UP Niridazole [61-57-4]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "SYN3,CDC14B,MPDZ,KSR1,SGCE,CFAP410,PICK1,WHRN,CNTNAP2,RIPOR2,EIF1,RRAGB,OLFM1,FGFR1,KHDRBS3,ERAP1,POLL,GPD1,RNFT2,NCKAP1L,MYCN,OPRL1,PFKFB4,PPARA,CEP41,RELN,WDR25,CEP97,FAT4,RGS12,RNASEL,TCP11L1,RBM34,HECW1,ZC3H13,ATP10B,SS18,SEPT8,CRTC1,AP4E1,ZNF34" Drug 3613_DN Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "AP2A2,NME5,LTBP4,DOC2A,APC,SLC4A4,SGCE,CNTFR,RCHY1,CNTNAP2,GREB1,DTNA,HIPK3,MRNIP,FGF13,ALDH1L1,GSN,HSF2,INPP1,INPP5B,JAK2,KIF2A,MATN3,SERPINI1,NLE1,PLCD1,LRP12,CARF,RPS6KA2,SBF1,ZKSCAN3,EXOC7,IQCE,SIN3B,AP4E1,SLC44A1,VGF,LMF1,GDPD5,ITM2C,PHTF2" Drug 5739_DN Cytisine (-) [485-35-8]; Down 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "CDC14B,CFLAR,CBFA2T2,SOCS6,ENTPD4,SLITRK5,PARD6A,EIF4G2,TENM1,ANKMY1,SCML2,FGFR1,PDLIM5,FAM49B,B4GALNT1,ZNF276,GPR37,RASSF8,KIF2A,MAP4,MAPT,MIA2,MAPK7,ELOVL2,FAM184A,GAL3ST4,SUGCT,MAPK12,AMBRA1,SIRT2,IFT122,KDM4C,ARHGAP26,SUPT5H,SYT1,IQCE,CHST8,GPR161,LMF1,TFIP11,EVI5" Drug 4825_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "APC,APOC1,RGS20,PDE8B,ALDH7A1,BAIAP3,CAMK2B,P2RX6,ARHGEF2,CRLF1,ASIC3,TAOK2,CLTB,MYRIP,CNTNAP2,FAM131B,RUSC2,EGFR,C3orf18,RASGRP2,EPHB1,CAMKK2,ERAP1,SIGLEC8,ALDH1L1,PCLO,ICA1,KCNH2,MID1,GPR173,PPP5C,PTPRD,NUDT11,CARF,ZFP30,LIMCH1,CRTC1,AP4E1,TMPO,UGT8,NT5M" Drug 7222_DN Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "AK2,FOXN3,HOMER3,ARHGEF6,CREM,SOCS5,APPL1,DMPK,SEZ6L2,FEM1B,COQ7,DENND4A,VPS26C,BAIAP2,FAM49B,INPP5K,TXNL4A,BTN2A1,RNFT2,INPP5B,MAPT,MBD1,MYO9A,SLC25A23,LRP12,RIPOR1,TMEM231,SUSD4,FBXW7,RPS6KA2,SBF1,NUBPL,DOP1A,SOX3,ZSWIM8,ERC1,ZBTB43,ASTN2,EVI5,EPM2A,RNF170" Drug 5686_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "APOC1,PDE8B,CA4,SRSF11,PLAA,BAG4,SIPA1L1,GIT2,ZNF804A,RCAN1,DTNA,ZNF589,BAIAP2,GALC,INPP5K,GLYR1,CLASRP,KCNF1,LSS,KITLG,MITF,ADAM22,ZNF862,PLXNB1,MINDY2,PRKAR1B,ZSCAN32,ZDHHC14,FERMT1,SYBU,BTBD7,ZHX3,THSD1,VPS13A,EXOC7,NSD1,RUNDC3B,FAM155A,LMF1,EVI5,EPM2A" Drug 4987_DN Khellin [82-02-0]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "SOCS6,B4GALT6,PLAA,TPP1,CNTNAP2,ARMCX2,JAKMIP2,SGSM2,RCAN1,HIPK3,FER,FGFR1,EFCAB2,INPP5K,MALT1,RAB30,POLL,GRIK5,ATXN2L,HNMT,ICA1,KCNN2,KITLG,NF1,PLCD1,MAPK7,SAMD9,TMEM104,ZNF821,RASA3,PREX2,PEX26,FAM214B,LIMCH1,UNC5B,LHPP,EXOC7,IQCE,DICER1,SLC44A1,KAT6A" Drug 5253_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "AMPH,APBB2,FAM131A,CDK13,SCAPER,NCOR2,DCAF4,MAML1,DAPK1,SPOCK3,DMPK,ST3GAL6,FHL1,DLL3,SIGLEC8,ALDH1L1,SRCAP,ADAM28,ATXN2L,TJAP1,KCNN1,PPARA,FAT4,TRIM68,MRAS,NLGN1,SLC2A5,FAM214B,KANSL3,PKNOX2,COA1,KDM4B,IZUMO4,ZNF423,ARC,EXOC7,SZT2,CHST8,CABIN1,TRIO,FLRT2" Drug 3673_DN Ofloxacin [82419-36-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASIC1,APAF1,CDK10,MARK4,RAB28,PLAA,RAB26,NCOR2,PHF14,TBC1D5,ARMCX2,DMPK,CDON,EZH1,ZNF589,FGFR1,FYN,TRAF3IP2,MSL3,ACOT7,INPP5B,KCNJ5,MAPT,NDP,CNOT4,SLC11A2,PPARA,CNTLN,CCDC40,ATXN2,FNDC3A,SS18,CEP68,ARC,COBL,EXOC7,TRIM2,TPM2,RPRM,VGF,LAT2" Drug 4257_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "MTUS1,BIN1,APBB2,CDK10,SLC4A4,SCARB1,SRSF11,CHN2,QKI,HOMER3,ENTPD4,ARHGEF4,DBT,KLHL3,PLPPR4,PARD6A,DYNC1I1,DPH1,FCF1,COQ7,SPEG,ETV1,FGF13,TRMO,GPD2,PCLO,HNMT,FAM69A,LIG4,NDP,PPP5C,PTCH1,FAT4,TCP11L1,AP1AR,SPTAN1,ZBTB43,SAMSN1,TRIM2,ZNF34,WIPF1" Drug 3563_UP Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "RALGAPA1,ADRA1D,AP2A2,BIN1,CDC42BPA,KCNAB2,CDC14B,ATP1A3,CAST,ARHGEF1,DLGAP1,PLEKHB1,TAOK2,EPS15L1,PHF14,INTS1,MYEF2,TMCC2,CNNM1,EGR3,TENM1,HSD17B14,PTK2B,KHDRBS3,INPP5K,ADAMTS13,KCNJ5,MAN2A2,ADAM22,NF1,OPRL1,POLG,PPP2R2B,PTPRH,C1orf54,RPS6KA2,MRAS,COA1,SNCA,ZC4H2,ARC" Drug 7378_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADCY6,CDC14B,NRP2,MTMR3,CACNA1A,CAST,FOXN3,CPS1,AKAP12,AATK,RUSC2,SPOCK3,EGFR,MRNIP,PIPOX,RRAGB,RUNDC3A,DHX35,IL6R,LSS,CLDN11,PALM,MAPK7,BCAS3,GDPD2,PTPRE,SUPT20H,CNKSR2,SLC8A1,ZHX3,DDN,SAMSN1,ARC,SYN2,ADGRL3,OBSL1,CABIN1,AMACR,TRO,SEMA3B,UBE3B" Drug 4663_DN Clioquinol [130-26-7]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "AMT,TAOK2,ABCG2,NRG2,NCOR2,ARHGEF10,VCAN,CNTNAP2,ARHGEF4,DCAF4,PLXNC1,ING4,ERCC2,FGFR1,ANKFY1,GLYR1,MSL3,POLL,CNTRL,DIDO1,LIG4,ADAM22,FSD1,SH3TC2,MAP6D1,SCN8A,ZNF821,ST6GAL1,TMCC1,KDM4B,RBM26,IQCE,TCF4,THRA,BHLHB9,TPM2,UBTF,TFIP11,EMSY,CIAPIN1,PHTF2" Drug 3802_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "BEGAIN,BCHE,NRP2,BMP7,CRMP1,PHF14,PPP6R2,C2CD2L,PARD6A,STX2,KCNMB4,INPP5B,ITGA7,KCNB1,LMO2,MAP2,MAPT,SLC11A2,PDE4A,PDE4B,PLXNB1,PTN,RGS4,ZNF821,RASA3,PREX2,ZNF334,CDK5RAP2,SNCA,KDM4B,ZHX3,DDN,COBL,CHST8,TNS1,AMACR,FLRT2,XRCC4,EMSY,NT5M,EVI5" Drug 6018_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "BIN1,APOC1,PLA2G4C,CFLAR,SRSF11,VCAN,PDE4DIP,RIMS2,CYBB,DMPK,HS3ST2,HIPK3,C3orf18,VPS13B,TBC1D16,BAIAP2,SRCAP,GFER,GPR75,GNAL,PCLO,ICA1,ZNF862,PPP1R1A,SEMA6D,SBF1,PPP4R3A,RBM34,ASTN2,TAL1,KIAA0930,ZEB1,RPGRIP1L,KAT6B,PIK3R5,TUBB1,VGF,LAT2,ZNF74,NT5M,KAT6A" Drug 3682_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG2,ADD2,AMH,GAS7,ARHGDIG,ATP2B2,KSR1,MYRF,LDB2,CHN2,NRXN3,HAPLN1,ABCG1,MFAP3L,DMD,EDN1,FRY,KAT8,ANKFY1,LILRA2,PADI2,IL12A,KCNN2,MARK1,MMP16,TAGLN3,LYRM9,NDP,NNAT,NPR2,PDE4A,MTRF1L,CNKSR2,SLC11A1,SLC14A1,SNAP25,SZT2,GPR161,TNS1,OSBP2,JPH3" Drug 4970_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG2,NME5,SPARCL1,BIN1,CDC42BPA,APLP1,SEMA4G,SLC2A11,SCAPER,CFAP410,CAMK2B,SLC16A4,STOML1,HOMER3,CSF1R,ARHGEF10,DMPK,EDNRB,HIPK3,ING4,FAM198B,FGF13,CGREF1,GLYR1,ADAMTS13,GSN,KCNN1,NNAT,P2RY1,GDPD2,ELOVL2,CARF,RPS6KA2,SH3GL3,PKNOX2,ARHGEF40,PLCB1,RIMBP2,CABIN1,TRIO,AMACR" Drug 7541_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADCY6,NME5,AMPD3,CFLAR,BAIAP3,NCOR1,FAM169A,DAPK3,GIT2,DBT,MFAP3L,FBXL5,FEM1B,ERCC2,F8,FGFR1,SCARA3,IQCG,EFCAB2,FYN,TMEM8B,GNG4,IRAK3,SMAD1,MITF,MX1,NF1,NFYA,PLCD1,MTRF1L,SNRK,WDR25,FAM184A,GTDC1,SH3BP2,KIF13A,CEP68,PLCB1,CRTC1,TMEM121,ZKSCAN5" Drug 987_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADRA1D,TRMT9B,BIN1,CDC42BPA,APC,GAS7,ADAM23,BAIAP3,LDLRAD4,TPP1,COL9A3,SLC4A8,ARHGEF4,EDN3,EIF4G2,HSD17B14,MTSS1L,GNAL,ATXN2L,LAMA2,LMO2,ZNF862,PPARA,MAPK10,SAMD9,ZSCAN2,SUGCT,SH3BP2,FAM214B,SLC9A5,SNCA,RBM34,KDM4C,OBSL1,TNS2,FAM155A,ZNF45,SLC17A7,PARP11,FAM13C,TIGD6" Drug 5540_DN Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADAM23,CFLAR,BAIAP3,ARHGAP33,B4GALT6,PLAA,FAM189A2,AKAP7,CSNK1E,GIT2,DPH1,MAMLD1,TNK2,EPB41L2,DLC1,FGFR1,FHL1,NOP56,CINP,PDLIM5,CNTRL,MAP4K5,LMO2,MIA2,MSI1,ADAM22,NEK1,PRKAR1B,MAPK7,ZNF821,PPP4R3A,BTBD7,SNCA,PJA1,EXOC7,FBXW11,AP4E1,PIK3R5,HIRA,FTSJ1,AAAS" Drug 6832_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "TRMT9B,KCNAB2,PPP4R4,ALDH7A1,CACNA1G,CA12,FAM149A,COL9A3,RCHY1,GREB1,HDAC9,GIT2,MBNL2,PLXNC1,IGSF6,PDLIM5,SEPT9,POLL,KCND1,MAN2A2,MID1,ZNF862,MYT1,TREM2,SERPINI1,ZSCAN2,CEP97,ZMAT4,TCP11L1,SEMA6D,SCN8A,SH3BP2,SLC2A5,PEX26,FAM214B,IZUMO4,ARHGAP26,TNS1,AMACR,VIPR2,NT5M" Drug 903_DN 5151277; Down 200; 14uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASPHD1,ABHD6,CDC42BPA,APAF1,SYNJ2,SPAG9,EPS15L1,STOML1,SMARCAL1,NCOR1,SOCS5,MTSS1L,SCML2,FGFR1,FHL1,ATP2C1,SEPT9,INPP5K,FERMT2,GPER1,JAK2,ADAM22,RETREG1,SMIM7,MBOAT7,SAMD9,CCDC25,SEC14L1,ASAP3,EPN2,LHPP,TROVE2,DIP2A,EXOC7,THRA,TIAM1,CABIN1,RPRM,ZNF24,GDPD5,TIGD6" Drug 3383_UP Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "FZD9,ADRA1B,ALCAM,ALK,KCNAB2,ARHGDIG,RASL11B,SLC4A4,GYG2,TPP1,COL9A3,ARHGEF10,SPOCK2,FYN,GAD1,SIGLEC8,GRIK5,PRDM5,GSN,GSTM5,AP4S1,MAN2A2,MATN3,KITLG,MX1,PFKFB2,PLXNB1,MAPK7,PTN,SH3BP2,ST6GAL1,SLC11A1,LIMCH1,ZC3H13,ATP10B,PCDHGA10,SYNE1,XRCC4,KAT6A,ADAMTSL3,SENP7" Drug 5259_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG2,ADORA1,NME5,AMPD3,CDC42BPA,ATP2A2,AZGP1,CDO1,CHN2,SULT4A1,LY86,CRMP1,SNCAIP,DCAF4,ECM2,SUGP2,F5,CORO2B,AFF2,ADAMTS13,GRIK5,PLCL1,PRKCB,PTN,PID1,SEMA6D,ASAP3,FAM214B,IZUMO4,TSPYL2,CLSTN2,STX1A,JMJD6,SYN2,SYT5,SLC19A3,PIK3R5,FAM155A,LAT2,EVI5,AP3B2" Drug 2833_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "SYN3,ADCY6,LTBP4,AMT,APAF1,APBB2,MARK4,BAIAP3,CACNA2D1,ZMYM4,ASIC3,CRMP1,ABCG1,C3orf18,HSD17B14,EZH1,FGFR1,BAIAP2,OGA,SRCAP,TDRKH,CACFD1,GSTM5,GUCY1A1,KHK,NTRK2,PDE4A,PRKAR1B,MAPK10,GDPD2,SH3BP2,SMARCC2,SNCA,SOX3,ATP10B,ARHGEF9,PLCB1,DICER1,TNS1,FAM155A,SPHK2" Drug 2506_DN Estropipate [7280-37-7]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG3,AMPD3,MARK4,SLC25A14,CAPN3,KRIT1,EPS15L1,HOMER3,BAG4,CSF1R,DBT,SPATA2,KIAA0753,F8,CELF1,CACFD1,FICD,MAP4K5,IL6R,ITPKB,LSS,MAP4,MATK,NF1,NFYA,RETREG1,LRP12,TMEM231,C1orf54,GTDC1,AMBRA1,NUBPL,WDR37,SPATA7,NSFL1C,JMJD6,VPS13A,TCF4,UBTF,FLRT2,ZNF32" Drug 2239_DN Nocodazole [31430-18-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG2,EPB41L5,APOC1,MADD,CFLAR,SLIT2,PICK1,AKAP7,BAG4,CSF1R,FAM169A,ARMCX2,TMCC2,CDON,RRAGB,FER,FGFR1,GPER1,GPR37,SPACA9,GRIK5,GSTM5,IL6ST,ITPKB,MSI1,ADAM22,MYO7A,NEK1,NFYA,PCDH9,CDK18,LRP12,SBF1,ZNF821,RCOR3,SNCA,CEP68,TACC1,TMEM121,SPHK2,REEP1" Drug 4693_UP Kawain [500-64-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ABHD6,ALCAM,AMPD3,CDC42BPA,SEMA7A,PLA2G4C,CFLAR,ST3GAL5,CHRNA4,CNN3,CREM,SIPA1L1,GIT2,EXOG,EDN1,RASGRP2,ZNF589,FHL1,OGA,TXNL4A,GLYR1,GPER1,KITLG,ADAM22,P2RY1,PFKFB2,SERPINI1,STRN3,ZSCAN2,C1orf54,RFX2,ASAP3,SMARCD3,KDM4B,PHLDB1,DMXL2,PCDHA6,RUNDC3B,ZNF24,SLC30A3,AP3B2" Drug 3738_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADD2,ADORA1,PPP4R4,SLC2A11,KSR1,BAIAP3,PICK1,FAM149A,CREM,NCOR2,SEMA3D,FRY,EGFR,RCAN2,IGSF6,CDKL3,GFER,POLL,GNAL,STON1,HLF,L1CAM,AFDN,NTRK2,PDE4D,PLXNB1,PPP2R2B,CEP41,RGS4,RPS6KA2,CSRNP3,FNDC3A,SLA,SPTAN1,NFASC,DMXL2,TRIM2,HEY1,TK2,PLSCR4,PARP11" Drug 7527_DN CP-645525-01 [287190-82-3]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "BRAP,NME5,CBFA2T2,ARHGAP22,FAM169A,DZIP3,GPRASP1,DTNB,APH1A,EIF5,FGFR1,FHL1,CINP,GLI2,HTATSF1,GPR37,JAK2,MMP17,CNOT4,SLC11A2,PDE1C,MAPK7,PTPRN2,TMEM231,GSTCD,MRAS,SH3BP2,KIF16B,AMBRA1,WDR47,COA1,MYH15,SPTAN1,LARP4,ARHGEF9,CHST5,HIRA,UBE3A,LMF1,XRCC4,RNF146" Drug 3256_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASIC1,LTBP4,PKP4,APBB2,PDE8B,MARK4,CBFA2T2,ENTPD4,DCTN1,RCAN1,DTNA,PLXNC1,RRAGB,ZNF589,FGFR1,GPER1,ICA1,INPP5B,ZNF862,NF1,PALM,PLCD1,MINDY2,PRKAR1B,MAPK7,RGS12,ZFHX4,SH3BP2,AMBRA1,BTBD7,PDZRN3,CAMTA2,TTBK2,TBCEL,RPGRIP1L,OBSL1,RUNDC3B,UCHL1,VLDLR,ZBTB14,KAT6A" Drug 6029_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA1,EPB41L5,FAM131A,CDC14B,SCAPER,MTMR2,C5,CRLF1,SOCS6,TAOK2,RAB28,PLAA,VAX2,CNTFR,AKAP7,CSF1R,SIPA1L1,GREB1,RASSF2,RCAN1,EGFR,ZNF589,INPP5B,JAK2,KCNN2,MMP16,MPP2,ADAM22,NEK1,SETD4,LRP12,MBOAT7,MAPK7,WDR25,ZFHX4,GSTCD,SGK1,PCDHA5,TK2,CABIN1,GAN" Drug 5670_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADCY6,ADRA1D,FAM131A,CDK13,BCL7A,CFLAR,CA4,CLGN,AKAP7,PDE4DIP,GPRASP1,JAKMIP2,MFAP3L,CDKL3,FAM198B,TRAF3IP2,GALC,AHDC1,HSF2,MATK,ADAM22,NEK1,NF1,SETD4,LRP12,PRODH,TMEM104,ZSCAN32,RAD51D,MSANTD2,RGS3,SH3BGR,ASTN2,RPGRIP1L,RUNDC3B,FAM155A,VGF,ZNF74,GDPD5,SMIM8,GAN" Drug 3816_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NME5,ATP1A3,ALDH7A1,NRP2,BMP7,IL33,CAMK2B,ARHGAP33,PLEKHB1,TAOK2,SLC4A8,NRG2,CRMP1,CRY2,CSF1,RIMS2,ARHGAP24,MFAP3L,ING4,TNK2,SPEG,PRELID3A,CGREF1,OGA,B4GALNT1,TMEM8B,TDRKH,ICA1,LAMA2,SCAMP5,TAGLN3,ZNF862,PTN,PTPRB,SNCA,SMG6,RPGRIP1L,DOCK9,HIRA,PLPPR2,ZNF74" Drug 5339_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA1,AK2,APC,GAS7,MADD,MARK4,CACNA1I,SCARB1,CACNA2D2,SULT4A1,LY86,C2CD2,CYBB,HDAC4,NCALD,KAT8,ZNF589,BAIAP2,OGA,BTN2A1,INPP5B,MAP4,ADAM22,ZNF862,NACA,NPTX1,NTRK2,PRODH,ROBO1,ZNF821,ZFP30,SH3BP2,ZKSCAN3,ZHX3,ZSWIM8,UNC5B,TRPM2,XRCC4,NDRG4,HPS4,MPPE1" Drug 4420_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NME5,APBA2,MARK4,SCAPER,KRIT1,LARGE1,RIMS2,PPP6R2,EXOG,DTNA,ING4,FER,FGF12,FHL1,SEMA4D,DISC1,MSL3,CNTRL,GRB10,INPP5B,KCNH2,TM6SF1,NF1,CNOT4,SERPINI1,RETREG1,PLCD1,PPP2R2B,RGS3,TCP11L1,ASAP3,FBXO11,EPN2,PHLDB1,TK2,HIRA,FLRT2,VLDLR,ZNF45,EMSY,EPM2A" Drug 4125_DN "Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA2A,AK2,LTBP4,APBA2,FAM131A,CFLAR,GYG2,CFAP410,CAMK2B,PLEKHB1,PLAA,QKI,ARHGEF4,RUSC2,MBNL2,ING4,TNK2,DLC1,TRAF3IP2,GLYR1,FERMT2,GRM8,IL6ST,MPP2,NTRK2,STRN3,LRP12,RGS12,TCP11L1,SEMA6D,FAM214B,TSNAXIP1,ZHX3,STX1A,PLCB1,KIAA0930,TNS2,AP4E1,PARD3,CABIN1,LMF1" Drug 3742_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "LTBP4,BEGAIN,RASL11B,SLC2A11,NRP2,BAIAP3,FOXN3,TAOK2,RAB28,VAX2,HOMER3,AATK,PHF14,DAPK3,DTNA,EGFR,BAIAP2,TDRKH,ICA1,ITPKA,KIFC3,MATN3,NNAT,NPTX1,PDE4D,PGAM2,PLXNB1,C19orf57,PRKAR1B,ELOVL2,KLHDC8A,SAFB,SH3BP2,FNDC3A,NFASC,ATP10B,SS18,ARC,ASTN2,TBL1X,TRIM2" Drug 4218_DN Pregnenolone [145-13-1]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "MTUS1,BIN1,APBB2,ARRB2,ST3GAL5,KYAT1,CLCN3,WHRN,BAG4,PPP6R2,DBT,PLPPR4,CHRDL1,EXOG,DYNC1I1,FCF1,PLXNC1,ZNF391,ETV1,FAM69A,MEF2C,NDP,CCSER2,LRP12,APTX,PTN,TMEM231,FNDC3A,LIMCH1,TMCC1,RBM34,SAMSN1,THSD1,ZNF34,SMUG1,SSBP2,VGF,LMF1,WIPF1,XRCC4,HPS4" Drug 5724_DN Mefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ABHD6,ADCY6,APOC1,ARRB2,C5,KYAT1,SOCS6,ENTPD4,SLITRK5,DZIP3,GIT2,RUSC2,SGSM2,EGFR,IRAK4,STX2,ERAP1,KCNMB4,GUCY1B1,MBD1,MX1,ZNF862,NDP,PDE1C,PFKFB2,SAMD9,TMEM104,PTCH1,ELOVL2,RGS3,CCDC25,AMBRA1,BTBD7,LIMCH1,SS18,COBL,FBXW11,CABIN1,ZKSCAN5,MAP3K12,EVI5" Drug 2862_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASIC1,AMPD3,PPFIA3,CFLAR,GYG2,TPP1,TBC1D5,DNAH9,EDN1,C3orf18,SPEG,ANKMY1,F5,DLC1,OLFM1,LYVE1,TDRKH,ADAMTS13,ATXN2L,ICA1,IFI16,KCNJ5,MAPT,PPARA,RELN,VPS13C,FAT4,TRIM68,KCTD17,SH3BP2,ASAP3,FAM214B,LIMCH1,DOK5,SP2,PEG10,SYN2,ZEB1,PARD3,LAT2,MKRN3" Drug 2236_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "BIN1,GAS7,APOC1,ZSCAN18,N4BP2L1,CFLAR,SYNJ1,LDLRAD4,CAMK2B,RAB33A,SULT4A1,FAM149A,WHRN,ARHGAP24,MBNL2,IGSF6,FGF12,FGFR1,DLL3,FYN,GATM,ALDH1L1,MSL3,GUCY1B1,IRF8,IL6ST,SMAD1,MAP2,MAP4,NELL2,PLCD1,STRN3,SAMD9,KLHL11,RASA3,THRA,R3HDM1,CABIN1,TNS1,TPM2,ITM2C" Drug 2705_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA1,BIN1,OGT,DNAH17,PTCH2,MPDZ,KSR1,CCK,NRXN3,COL4A5,SIPA1L1,CNTNAP2,PYGO1,DAPK3,RASGRP2,OLFM1,PRELID3A,CSPG5,SIGLEC8,SEPT9,PRUNE2,KCNF1,MAPT,MBNL1,AFDN,MPP2,MYO7A,NPY,NOVA2,PGAM2,PPP2R2B,GRAMD1C,GDPD2,GAL3ST4,SNAP25,PLCB1,PCDHA5,CHST8,MKRN3,SPHK2,KAT6A" Drug 837_UP (+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "FZD9,APLP1,PPFIA3,SLC2A11,N4BP2L1,CFLAR,ST3GAL5,CAMK2B,LRRFIP1,DBT,SPOCK3,SLC12A6,MBNL2,PLXNC1,FAM49B,ALDH1L1,GLYR1,TDRKH,LPAR4,GRM8,BTN2A1,GSN,KCNH2,KIF2A,LIG4,AFDN,ADAM22,MYT1,RETREG1,ZSCAN32,RGS12,RPS6KA2,EMID1,NLGN1,BTBD7,ERC1,ARHGAP26,ZBTB43,TACC1,REEP1,EVI5" Drug 2783_UP Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "NDRG2,NME5,ALCAM,LTBP4,CDK13,MARK4,GYG2,CACNA1I,HAP1,PICK1,CNTN1,INTS1,DTNA,MBNL2,FHL1,PDLIM5,GABRG2,LUZP2,GPER1,GSN,ATXN2L,KCNN2,KHK,MAP4,PDE4B,FA2H,PRODH,KCTD17,RPS6KA2,EMID1,ZNF821,CPEB3,SMARCC2,PEG10,IQSEC2,SMG6,KIAA0930,PCDHA5,SLC44A1,CA14,HIRA" Drug 4547_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "APBB2,MARK4,PTCH2,SLC4A4,NRP2,ST3GAL5,CAPN3,CBFA2T2,SCARB1,SEPT7,CACNA2D2,B4GALT6,EPS15L1,RGS6,ABCC5,EDN1,NRN1,ST3GAL6,ZNF589,GPD2,PRUNE2,ATXN2L,ELOVL5,ICA1,JAK2,KCNN1,LIG4,MGAT3,NF1,PDE4B,PDE4D,PTPRN2,MARCH1,KHDRBS2,ZNF415,PDZD2,LHPP,DOCK9,TPM2,VGF,VIPR2" Drug 3536_DN Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "BEGAIN,AMPD3,KCNAB2,CDC14B,RASL11B,CFLAR,CAMK2G,LHX2,RAB28,IQCK,LRIG1,RUSC2,TSPAN5,EDNRA,CELSR3,NCALD,ANKMY1,FER,FGFR3,SCARA3,FLNC,GAD1,DISC1,TDRKH,MUM1,INPP5B,KCNH2,IPO5,NNAT,NPR2,PALM,RETREG1,POLG,PRODH,RGS12,SEMA6D,ASAP3,PHLDB1,VPS13A,TMEM121,ZNF34" Drug 2005_DN Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADD1,BRAP,PKP4,MTMR2,ZMYM4,TAOK2,DCAF8,ZNF337,EPB41L2,IGSF6,FAM49B,FYN,TRAF3IP2,LILRA2,JAK2,MYO9A,NACA,NEK1,OCRL,GPSM2,STRN3,MAPK3,VPS13C,C1orf109,C1orf54,ATXN2,FAM214B,CCDC88A,KBTBD4,SMARCA4,SMARCC2,DOP1A,UNC5B,SPTAN1,ATP10B,DIP2A,MCF2L,FAM208A,HIRA,LAT2,ZNF24" Drug 7092_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASIC1,MTUS1,LTBP4,CDK10,MARK4,BMP7,SYNJ2,ENTPD6,WHRN,CRY2,CSNK1E,PDE4DIP,GIT2,SUGP2,MRNIP,ERCC2,SEMA4D,OGA,SRCAP,DIDO1,ADAMTS13,ATXN2L,IL6R,IL6ST,KCNH2,MAN2A2,MAP4,LYRM9,CDK18,PIK3R1,CNNM2,RNASEL,RXRA,ZNF821,ZHX3,ZBTB43,POGZ,SS18,VPS13A,VLDLR,LMF1" Drug 6058_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "KCNAB2,EPB41L5,ARRB1,SYNJ2,CAMK2G,ARHGEF1,SCARB1,SRSF11,HOMER3,ARMC8,CRY2,GREB1,DCAF8,TBC1D5,FBXL5,KAT8,FGFR3,GLYR1,RAB30,TDRKH,HNMT,IL6ST,ADAM22,OGG1,NLE1,PRKAR1B,CNNM2,NEK11,FBXO11,WDR37,SPTAN1,TSPYL2,SPART,PHLDB1,VPS13A,PLCB1,TACC1,EXOC7,REEP1,EPM2A,ST7" Drug 4689_DN Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA2A,DOC2A,BIN1,APBA2,MARK4,BMP7,CA4,B4GALT6,CLCN3,VAX2,ARMC8,BRINP1,JAKMIP2,RCAN1,MBNL2,AASS,ACSL4,ST3GAL6,BAIAP2,FHL1,SEMA4D,PDLIM5,FAM49B,SEPT9,GFER,GNG4,GRM8,HSF2,IPO5,ADAM22,NF1,PIK3R1,SLC25A23,SAMD9,PTN,MAPK12,VPS13A,THRA,SPHK2,DNALI1,KAT6A" Drug 4574_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "RALGAPA1,ASPHD1,ADD2,C1QTNF3,PTCH2,BMP7,FUBP1,MTMR3,BAIAP3,KRIT1,USP2,AKAP5,CREM,PDE4DIP,CNTNAP2,PHF14,MFAP3L,C2CD2L,AASS,MTSS1L,ZNF549,DLC1,ST3GAL6,FGF1,FGFR1,ZNF44,SIGLEC8,AP4S1,ITGA7,MSR1,PALM,RGS4,PNMA8A,ZFP30,TROVE2,PCDHA5,TK2,WIPF1,REEP1,ZNF225,PARP11" Drug 4628_DN Crotamiton [483-63-6]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADRA1D,TRMT9B,BIN1,AMT,APC,ATP2B2,CACNA1I,CFAP410,SCARB1,SYNGR3,LARGE1,TAOK2,QKI,HOMER3,ARMC8,MBNL2,FGFR1,CINP,ZNF44,MSL3,INPP5B,MITF,NF1,NNAT,PDE4D,FA2H,GRAMD1C,PTN,TMEM231,ATXN7,FRMPD1,SIRT2,CCDC88A,IQSEC2,ZBTB43,THSD1,TRIM2,RIMBP2,RUNDC3B,XRCC4,EVI5" Drug 7142_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "SLC4A4,B4GALT6,TPP1,ENTPD4,DCAF8,KLHL3,EDIL3,SUGP2,C3orf18,FGFR1,ATP2C1,GCNT2,HTATSF1,RNFT2,MEIS1,MPP2,OCRL,OGG1,PIK3R1,LRP12,RIPOR1,TMEM231,NCBP3,SMARCC2,SPATA7,FNBP1,ARHGAP26,ZBTB43,ELOVL4,SEPT8,DIP2A,STX1A,ARHGEF9,TRIM2,SSBP2,HIRA,LMF1,XRCC4,ZNF45,UPF3A,IFT88" Drug 5455_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADRA1D,PDE8B,KIF1A,BMP7,SCAPER,BAIAP3,CBFA2T2,CLGN,SIPA1L1,GREB1,MAML1,NCALD,FGFR1,FHL1,IP6K2,OGA,GPER1,CNTRL,IL6ST,MAPT,ADAM22,NF1,NLE1,LRP12,MBOAT7,PRODH,RGS12,SBF1,BTBD7,SMARCA4,ZSWIM8,TTBK2,PLCB1,TRIM2,BHLHB9,PARD3,CABIN1,KCNK12,SPHK2,UPF3A,KAT6A" Drug 6460_DN Florfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "OSBPL1A,AMH,AMT,APOC1,RIPK1,ARHGEF7,LDLRAD4,CA12,ABI3BP,BAG4,NECTIN3,USP6NL,ARMCX2,IRAK4,COQ7,SCML2,FAM49B,DISC1,FERMT2,STON1,BTN2A1,HNMT,IPO5,ZNF862,NF1,NPTX1,RETREG1,FSD1,ELOVL2,CEP97,RAP1GDS1,RGS12,SEC14L1,SS18,IQCE,KIAA0930,BEX4,SSBP2,ZKSCAN5,LMF1,MPPE1" Drug 2628_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ADORA2A,ALCAM,SEMA4G,MARK4,RASL11B,KSR1,CFAP410,CA4,NRXN3,SULT4A1,NCOR2,LRIG1,MFAP3L,TMCC2,EDN3,EDNRA,PLXNC1,STX2,EZH1,ZNF589,ATXN2L,PCBP3,PFKFB2,NLE1,MBOAT7,PRODH,KCTD17,SH3BP2,KANSL3,SLC11A1,SMARCD3,DOP1A,SPTAN1,IQSEC2,SAMSN1,ST5,WSCD1,TK2,AMACR,TRPM2,ADAMTSL3" Drug 4100_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-05 1.00E+00 1.19E-03 1.34E-02 41 196 "ASIC1,MTUS1,BIN1,CDC42BPA,APC,PPFIA3,ATP1A3,CACNA1I,MYRF,BAIAP3,PLEKHB1,LHX2,HOMER3,ENTPD4,SLITRK5,BRINP1,MFAP3L,CELSR3,SUGP2,EIF4G2,MTSS1L,DLC1,FGFR1,ZNF44,GLI2,GNAL,GPER1,MYT1,NPR2,PLXNB1,MBOAT7,MRAS,SLC4A3,KDM4C,DIP2A,EXOC7,KIAA0930,DNAH7,TK2,TRIO,NT5M" Drug CID000030956 AC1L1KMJ Stitch 7.72E-05 1.00E+00 1.19E-03 1.34E-02 82 476 "ACTN1,ADD1,ANK2,MYH7B,GAS7,SPTBN4,DST,CALM1,CAST,LRBA,CDH2,EPS15L1,MYL6B,CLTC,CNTN1,CABP1,COL4A5,COL9A1,COL9A3,COL11A2,MYRIP,AKAP12,DBN1,DCTN1,SACS,DNM1,DNM1L,EDN1,TNK2,TUBD1,VPS13B,APC2,PTK2B,TUBB3,BAIAP2,DCTN2,FYN,TUBA8,GSN,PSIP1,MYLK2,IGF1,ITGAM,LAMA2,MAP2,MATK,TAGLN3,MYO6,MYO7A,PIK3C2A,PIK3R1,PKD1,PLEC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PSMA6,LAMA1,PTK2,PTPRB,RDX,FBXW7,RPS6KA2,CLIP1,MAPK12,FNDC3A,SLA,SLC9A5,SLC12A2,SPTAN1,SPTB,JMJD6,TIAM1,ACTR6,TPM1,TPM2,TUBB2A,TUBB1,VAV1,TUBA1A" Drug 1951_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A" Broad Institute CMAP Up 7.79E-05 1.00E+00 1.20E-03 1.35E-02 38 177 "ABHD6,ADRB2,SHROOM2,ARNTL,HIP1R,SPAG9,AKAP12,CTH,C2CD2L,ANKRD46,TAOK3,BAIAP2,NBEA,FYN,RAB40B,GPR37,GUCY1B1,HMGCR,MEF2C,AFF1,MYO6,PCDH9,RETREG1,PLCD1,SMOX,RGS4,NUDT11,SBF1,SH3GL3,KDM4B,DOP1A,RGL1,SYT1,AGTPBP1,TIAM1,HEY1,TNS1,PLSCR4" Drug 1555_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 7.79E-05 1.00E+00 1.20E-03 1.35E-02 38 177 "NDRG2,ALCAM,BIN1,GAS7,ARRB2,DNAH17,CFLAR,CD86,CD38,ARHGAP33,CHN2,PICK1,AATK,CSF1R,PPP1R16B,RUBCN,DOCK4,MED12,FAM13A,RUNDC3A,ITGAM,NCF2,NTRK2,PDE4B,SMOX,PTPRE,SEC14L1,SGK1,SLA,SLC2A5,ARHGEF40,SPTAN1,CDK19,TSPYL2,SAMSN1,PLCB1,PDLIM2,CLDND1" Drug ctd:C514793 "gp120 protein, Human immunodeficiency virus 1" CTD 7.93E-05 1.00E+00 1.22E-03 1.38E-02 12 31 "ARRB2,SLC4A8,SV2B,LUZP2,KIF5A,NPY,NTRK2,ROBO2,FAM81A,NECAB1,SLC35G2,VGF" Drug 1971_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "APBB2,ARNTL,MARK4,BACH1,WASF1,CAST,HIP1R,LRBA,UBE2L6,PREPL,DPYSL2,FAM13A,EXTL2,FECH,PDLIM5,FYN,ARFIP1,IFI16,ITGA7,MEF2C,NEK1,NTRK3,SERPINI1,GPSM2,PTK2,SPDL1,C1orf54,SGK1,CCDC88A,SPTAN1,TSPYL2,THSD1,ZC4H2,CEP68,RGL1,STXBP1,ZEB1,PLPPR2,ATP6V0E2,ITM2C" Drug 914_UP rottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "SPARCL1,CDC14B,RASL11B,CA4,ARHGEF2,LARGE1,CLGN,BAG4,CELSR3,ING4,CDKL3,ST3GAL6,SIGLEC8,RUNDC3A,GPD2,LPAR4,GRB10,KPNA5,PACRG,MID1,MITF,NF1,MAPK7,PRPH,C1orf54,RGS12,RPS6KA2,FNDC3A,NLGN1,ANKRD6,LIMCH1,UHRF1BP1L,TSPYL2,CAMTA2,THSD1,RUNDC3B,PLPPR2,VLDLR,WIPF1,NT5M" Drug 6844_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "BIN1,RGS20,BAIAP3,HIP1R,ARHGEF2,CLGN,SULT4A1,WHRN,NECTIN3,CREM,CYBB,HS3ST2,DTNA,SNX29,C3orf18,ENO2,TPPP,GRB10,GRM2,IL6R,MX1,ZNF862,TMOD2,PTCH1,ZSCAN2,RGS12,TCP11L1,SH3BGR,ASAP3,FAM214B,BTBD7,TSNAXIP1,IZUMO4,WSCD1,ZEB1,UCHL1,VLDLR,XRCC4,KCNAB1,KAT6A" Drug 5237_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "AK2,APC,ARRB1,PDE8B,STX16,CFLAR,CACNA1I,CAMK2G,SPAG9,SCARB1,SLC4A8,DTNA,YAF2,SUGP2,ANKFY1,PDLIM5,FAM49B,OGA,GFER,GNG4,STON1,CNOT4,NPR2,NRCAM,LRP12,PRODH,ZNF430,MAPKBP1,SNCA,TROVE2,POGZ,NXT2,DIP2A,DICER1,TMPO,VIPR2,HPS4,SEMA3B,PHTF2,SENP7" Drug 2887_UP Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "AK2,BIN1,APBB2,APOC1,RGS20,SLC2A11,CFLAR,CACNA1I,CA4,CA12,CBFA2T2,TAOK2,ARMCX2,RUSC2,ERBB2,VPS26C,FAM198B,PTK2B,BAIAP2,OGA,ALDH1L1,SRCAP,LYVE1,GPR37,ICA1,IL6ST,KCNJ5,MIA2,NF1,SLC25A23,MTRF1L,CEP41,RASA3,ARHGEF40,LIMCH1,TSNAXIP1,ZBTB43,TACC1,DMXL2,HIRA" Drug 4493_DN Securinine [5610-40-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.09E-05 1.00E+00 1.25E-03 1.40E-02 40 190 "SHROOM2,IL33,KYAT1,SCARB1,B4GALT6,LHX2,SLITRK5,SNPH,EGFR,ING4,MRNIP,STX2,ETV1,EZH1,ZNF589,SEMA4D,SYT17,SEPT9,POLL,GPD2,GUCY1B1,LSS,MX1,NDP,PAX6,PTCH1,PTPRE,PTX3,MCMBP,ASAP3,SPATA7,TCF4,KIAA0930,TRIM2,TNS2,TMEM121,TNS1,METTL3,ZBTB14,TRIM9" Drug CID006450319 polysialoganglioside Stitch 8.16E-05 1.00E+00 1.26E-03 1.41E-02 16 50 "SYN3,ADD2,CA12,SIGLEC8,NEU3,NTRK3,CLDN11,PKM,PRODH,FNDC3A,SNAP25,SYN1,SYN2,SYT1,NEU4,SIGLEC10" Drug CID000435143 NSC-364372 Stitch 8.22E-05 1.00E+00 1.26E-03 1.42E-02 83 484 "APBA2,APC,CDK10,NCOA1,ATP6V1G2,HCN2,BID,CFLAR,KSR1,CCNT1,CDC25B,NUMBL,EPS15L1,CLTC,QKI,RCHY1,CREM,SH2B1,CRY2,CSNK1E,CSNK1G3,HDAC9,HDAC4,MED12,DYNC1I1,DUSP9,E2F5,TMTC1,APC2,PPP1R1B,UBE2E3,FOXO3,DCTN2,KHDRBS3,FYN,GCK,MALT1,ZNF276,TCERG1,COPS8,CBX1,GRB10,PACSIN2,DDX19B,SYNPO,IGF1,ITPKB,KPNA5,IPO5,LIMS1,MXI1,NACA,BEX5,NFE2L2,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTH1R,KHDRBS2,GSTCD,FBXW7,RXRA,MAPK12,FOXRED1,EPN2,PKNOX2,SIRT2,SNRPN,HECW1,KANK1,SYT1,SIRT1,THRA,SYNPO2,NEIL2,UBC,EIF4ENIF1,XPO1,TUBA1A,FXR1,JPH3" Drug 2136_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.38E-05 1.00E+00 1.29E-03 1.45E-02 36 165 "MTUS1,BIN1,GAS7,DNAH17,CD86,CD38,CHN2,CREM,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,DOCK4,GSDME,FAM13A,PLXNC1,OLFM1,BAIAP2,PRKAG2,TRAF3IP2,ICA1,MEF2C,LYRM9,ZNF862,PDE4A,PDE4B,SGK1,ARHGEF40,ZHX3,SPTAN1,TSPYL2,PLCB1,ICAM5,RUNDC3B,FLRT2,CLIP2" Drug 2711_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.46E-05 1.00E+00 1.29E-03 1.45E-02 39 184 "NDRG2,C1QTNF1,BIN1,DNAH17,CD86,CD38,CDO1,CHN2,SULT4A1,COL9A3,CREM,ABCG1,SIPA1L1,VCAN,PPP1R16B,PHF14,DOCK4,SNPH,DBT,FAM13A,PLXNC1,LILRA2,CACFD1,KIFC3,MEF2C,AFDN,PLCD1,CEP41,PRKAR1B,PTK2,ACSS3,PBRM1,RPS20,SLC14A1,TMCC1,GPR161,TLR4,UBE3A,ZBTB38" Drug 6919_UP scriptaid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.46E-05 1.00E+00 1.29E-03 1.45E-02 39 184 "ADRB2,NME5,ARNTL,ST3GAL5,CLCN3,ABCG1,OSBPL3,PDE4DIP,CTH,ANKRD46,TBC1D16,FDFT1,BAIAP2,PDLIM5,FYN,RAB40B,AGFG1,L1CAM,LSS,MMP16,SERPINI1,PRKACB,ELOVL2,PTPRH,RBBP6,RGS4,RPS6KA2,SEC14L1,WDR47,ELMO2,KDM4B,DOP1A,ARHGAP26,THSD1,ELOVL4,RGL1,SYT1,ANKRD12,PLSCR4" Drug 2809_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ARHGDIG,CDK13,PTCH2,CFAP410,CAMK2B,SULT4A1,AKAP6,WHRN,CRMP1,CSNK1E,ARHGEF4,ARMCX2,EDIL3,MBNL2,EIF4G2,STX2,FCGRT,EFCAB2,PDLIM5,FYB1,ERAP1,SEPT9,ICA1,KCNN1,AFDN,CNOT4,PCDH9,PLCD1,PLTP,PPP5C,KHDRBS2,ARHGEF40,PDZD2,SPTB,ST5,CABIN1,FAM155A,UBE3A,PLPPR2,SLC30A3,SEMA3B" Drug 7301_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "PPFIA3,CDK13,CFLAR,ST3GAL5,HIP1R,CHN2,WHRN,ABI3BP,PDE4DIP,DZIP3,FAM131B,ZNF804A,LYPD1,DNM1,CDON,ACOT8,AASS,COQ7,CINP,GRB10,GUCY1B1,MEF2C,SNX10,PLCD1,PTX3,TMEM231,RAD51D,SH3TC2,MAPK12,SBF1,ST5,PHLDB1,PDLIM2,TRIM2,FRYL,METTL3,SSBP2,FAM155A,WNT7A,XRCC4,NAV3" Drug 5770_DN Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APLP1,CDC14B,SYNJ2,SCAPER,C5,CAMK2B,DZIP3,ARHGEF4,DCAF4,GPRASP1,DCAF8,SPATA2,RUSC2,FGFR1,ANKFY1,FAM49B,TRAF3IP2,DISC1,SRCAP,ZNF276,TJAP1,MATN3,NPR2,TMEM231,GSTCD,FBXW7,BTBD7,SMARCD3,SPTAN1,ZBTB43,THSD1,ELOVL4,SYT1,IQCE,HIRA,NPDC1,XRCC4,NDRG4,NT5M,VPS35L,KAT6A" Drug 6928_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABHD6,PPFIA3,AQP6,ARHGDIG,ATP2A2,ALDH7A1,SGCE,CACNA1I,USP2,FAM149A,NRG2,FAM169A,HDAC4,LYPD1,CDON,EDNRA,EGR3,ABCA8,ACSL4,FGFR1,SEMA4D,GLI2,IL6ST,NNAT,NOVA2,PDE4A,RETREG1,NLE1,PPP2R2B,PTN,EMID1,FRMPD1,TSNAXIP1,KDM4C,CLSTN2,PLCB1,IQCE,DOCK9,CDK20,KCNK12,HPS4" Drug 7477_DN Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AK2,CDC42BPA,MARCH3,B4GALT6,STOML1,HOMER3,CSNK1E,SOCS5,PDE4DIP,PPP6R2,DCAF8,KIAA0586,GIT2,C2CD2L,CGREF1,SEPT9,GRB10,PADI2,ATXN2L,HNMT,MITF,N6AMT1,SETD4,PRKAR1B,NKAIN1,RAD51D,CCDC25,PEX26,ZKSCAN3,ZBTB43,TACC1,TRIM2,NPL,VGF,VIPR2,LMF1,NDRG4,EMSY,GDPD5,ST7,UBE3B" Drug 3793_UP Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADD2,LTBP4,TRMT9B,APAF1,LGR5,CDC14B,PDE8B,ATP6V0A1,KSR1,CACNA1I,RAB26,ARHGEF4,DMPK,DTNA,HEYL,TNK2,RASGRP2,EZH1,GALC,GLI2,TOX3,PRUNE2,GRIK5,KCNF1,KCNJ5,ADAM11,CDK18,PDE4D,PFKFB2,C19orf57,DCHS2,ZMAT4,KLHL11,SLC2A5,PKNOX2,HECW1,TPM1,CA14,SPHK2,SLC30A4,SLC17A7" Drug 6819_DN Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "RALGAPA1,ADCY6,ALCAM,CDK10,ARHGDIG,ATP6V0A1,CFLAR,BMP7,GYG2,SCARB1,TAOK2,PLAA,NCOR1,CSNK1E,RIMS2,DBN1,DCTN1,ACOT8,DTNA,PHC2,FER,ANKFY1,OGA,POLL,CNTRL,CACFD1,INPP5B,MAP4,KITLG,PCDH9,RETREG1,PPP5C,NKAIN1,PHLDB1,SYT1,IQCE,ZNF34,NDRG4,MPPE1,EPM2A,ST7" Drug 4077_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "SYN3,LTBP4,AMT,PKP4,APAF1,PPFIA3,NRP2,SCAPER,TPP1,STOML1,DCAF4,CYBB,C2CD2L,DMPK,FRY,PRELID3A,GABRB3,SRCAP,CACFD1,IRF8,IL6R,MIA2,NF1,NPR2,CLDN11,PFKFB2,PLCD1,PTN,GSTCD,RPS6KA2,SEMA6D,ZNF821,STUM,ZNF334,KIF13A,ATP10B,PHLDB1,ARC,TBCEL,SYNE1,TNS1" Drug 6372_DN 3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "TRMT9B,CDK13,ADGRB3,CFLAR,BMPR1B,CACNA1I,MYRF,HAP1,USP2,RAB28,QKI,AATK,PDE4DIP,EDN1,EGFR,ING4,TNK2,ETV1,FGF1,ANKFY1,DCTN2,ZNF276,GPD2,GPER1,TJAP1,MAPT,MATK,NTRK2,PALM,GPR85,STRN3,LRP12,KIRREL1,RPS20,SCN8A,PEX26,TBL1X,CRTC1,HIRA,LAT2,MPPE1" Drug 4192_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "DDO,CDC14B,BACH1,CACNA2D1,ARHGEF2,WHRN,NCOR2,ARHGEF10,PDE4DIP,CNTNAP2,MAML1,SPOCK2,TNK2,PIPOX,CORO2B,GNAL,KCNJ5,MAP2,MAPT,AFDN,CNOT4,NPTX1,PDE4A,PFKFB2,ZSCAN32,RFX2,FNDC3A,DZIP1,PREX2,OGDHL,SNCA,TSNAXIP1,ZSWIM8,IZUMO4,RBM26,ARC,PCDHA5,TLR4,TPM1,VSNL1,KCNK12" Drug 4152_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APBA2,CDC14B,LDB2,AKAP6,VCAN,CTH,CYBB,SPOCK3,DMD,DMPK,SPEG,SCML2,NSG1,OGA,ZNF44,PCLO,ICA1,TJAP1,ITGA7,MEF2C,MYO9A,NTRK2,PPP5C,APTX,PTCH1,ENOX1,RPS6KA2,STUM,ST6GAL1,KDM4B,PDZD2,IQSEC2,CDK19,RBM26,SYN2,PCDHGA10,HIF3A,TEK,R3HDM1,LAT2,NT5M" Drug 3338_DN "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "OSBPL1A,AK2,CDC42BPA,APC,CDC14B,NUMB,MPDZ,BCL7A,SCAPER,RAB28,STOML1,SIPA1L1,MFAP3L,DNM1,DTNA,SUGP2,IRAK4,INPP5K,MALT1,TXNL4A,CACFD1,MUM1,FAM69A,INPP5B,KCNH2,MBNL1,MIA2,ZNF862,NF1,TMEM231,RNASEL,CCDC25,AP1AR,NUBPL,TMCC1,ITPRID2,ASTN2,ZNF34,ZBTB14,REEP1,SMIM8" Drug 3319_UP Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADRA1D,BIN1,APC,APLP1,SLC4A4,LDLRAD4,P2RX6,CDH2,TAOK2,STOML1,AKAP7,WHRN,CSF1,SPOCK2,ELMO1,MFAP3L,SLC12A6,MBNL2,PLXNC1,LRRC17,SPEG,NSG1,DISC1,ALDH1L1,GFER,POLL,GRM8,MMP16,NF1,CNOT4,FRMPD1,SLC11A1,ZSWIM8,EXOC7,SYNE1,TNS2,PIK3R5,FAM155A,VIPR2,KCNK12,KCNAB1" Drug 4265_DN Succinylsulfathiazole [116-43-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "RALGAPA1,APBB2,APOC1,SHROOM2,CDK10,SEMA4G,ST3GAL5,CHN2,RAB26,CNTNAP2,PLPPR4,ETV1,RRAGB,FGF1,FGFR1,PRELID3A,CNTRL,HNMT,SHISAL1,FAM69A,TM6SF1,MIA2,MX1,NF1,CNOT4,PIK3R1,PLCD1,PRPH,PTCH1,KCTD17,AP1AR,MAPK12,SMARCD3,KIF13A,TCF4,CRTC1,WIPF1,XRCC4,EVI5,KCNAB1,PARP11" Drug 4754_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "FZD9,AMPD3,CDH2,CRLF1,CHN2,EPS15L1,CNN3,AKAP7,MYRIP,CPS1,CSF1,RUSC2,C2CD2L,PLXNC1,C3orf18,EPHB1,CDKL3,REEP2,FHL1,FYB1,ZNF44,GNAL,PACRG,SMAD1,MTRF1L,EMID1,RPS20,RASA3,KANSL3,LIMCH1,ZNF415,RBM26,SPART,ZEB1,PARD3,TPM1,CHST5,TUBB1,KCNK12,SLC30A3,DNALI1" Drug 5884_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG3,PDE8B,MARCH3,CFLAR,SPAG9,LRRFIP1,CNOT8,DAPK3,DBT,PLXNC1,EIF5,IRAK4,COQ7,CDKL3,ETV1,F8,FHL1,ZNF276,PRRC2B,MAP4K5,FAM69A,INPP5B,MAPT,MITF,MPP2,NFYA,SLC11A2,CCSER2,ZNF426,PID1,FNDC3A,SMARCA4,SNCA,TEX2,EXOC7,TBL1X,NR2C2,AMACR,PLPPR2,MAP3K12,PLSCR4" Drug 3831_DN Deltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADORA2A,ADRA1D,ALCAM,BIN1,BCL7A,CA4,ARHGAP33,TAOK2,AKAP12,CSF1,RIMS2,CNNM1,MBNL2,HSD17B14,SRCAP,ATXN2L,IL6R,ADAM22,NPR2,NPTX1,PFKFB2,PLCD1,FSD1,PRKAR1B,SNRK,ZSCAN2,TMEM231,ENOX1,EMID1,PREX2,SLC22A4,SNCA,SPTAN1,LHPP,CLSTN2,ST5,SYN2,CHST8,CABIN1,LAT2,ZNF45" Drug 5939_UP PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,LTBP4,APOC1,CDC14B,BACH1,SCAPER,BAIAP3,CAMK2B,COL9A3,DAPK3,ING4,TUBD1,EZH1,REEP2,PTK2B,FYB1,SESN1,TXNL4A,SCIN,ITPKA,MAPT,ZNF862,CDK18,PIK3R1,CNNM2,CNTLN,ZCWPW1,KCTD17,RPS6KA2,ATXN7,SH3BP2,FBXO11,BTBD7,IQSEC2,CEP68,CHST8,TK2,TNS1,MKRN3,MAP3K12,FZD3" Drug 4679_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APC,SPTBN4,ARRB1,ARSE,ATP2B2,CFLAR,SYNJ2,DLGAP1,CHRNA4,AKAP5,RIMS2,DMPK,TOM1,APC2,EZH1,REEP2,DLC1,TRAF3IP2,ALDH1L1,GPD1,ATXN2L,ELOVL5,IL6ST,KIT,MIA2,P2RX7,TREM2,PFKFB4,MTRF1L,CNNM2,FAM184A,PNMA8A,SH3BP2,CNKSR2,FAM214B,SLC12A4,SYN2,PCDHGA10,LAT2,KCNK12,KCNAB1" Drug 4642_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "TRMT9B,APC,DDO,ATP2B2,ADGRB2,CACNA1I,BAIAP3,LDLRAD4,CAMK2B,ABCG2,CABP1,NRG2,CSF1R,SGSM2,DTNA,DTNB,HEYL,ETV1,F5,FGFR3,AFF2,FAM49B,FYN,ZNF44,SIGLEC8,GRM8,IL12A,MGAT3,PRKAR1B,ELOVL2,PTPRB,KHDRBS2,SCN2B,FRMPD1,ASAP3,KDM4C,ADGRL3,THRA,REEP1,NT5M,SEMA3B" Drug 3039_UP Equilin [474-86-2]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "HAP1,DGKI,PLEKHB1,AKAP6,ARHGEF10,DZIP3,RIMS2,RIPOR2,SNPH,INTS1,BRINP1,TMCC2,CHST15,OLFM1,CAMKK2,GALC,B4GALNT1,TMEM8B,SIGLEC8,RUNDC3A,GRIK5,GUCY1A1,SCIN,AFDN,NOVA2,OPRL1,PDE4D,PRPH,RELN,SEMA6D,SCN7A,PKNOX2,IZUMO4,ZC3H13,ARHGAP26,SPTB,DNMBP,TBCEL,TIAM1,ICAM5,TRO" Drug 5049_UP Indomethacin [53-86-1]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASIC1,NDRG2,AMH,PPFIA4,CDK10,ARHGDIG,CACNA1G,CACNA1A,KALRN,TAOK2,BRINP1,MFAP3L,DUSP9,RASGRP2,MTSS1L,ST3GAL6,FGF1,FGFR1,GLI2,GNAO1,CACFD1,HLF,KCNN1,CNNM2,RGS12,ZFP2,SLA,SLC8A1,SNCA,DOK5,SPTB,ZBTB43,DDN,ATP10B,PHLDB1,KLHL4,PCDHA5,TLR4,PIK3R5,VGF,NT5M" Drug 6291_DN Chlorpropamide [94-20-2]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "BIN1,PPFIA3,MARK4,MTMR3,KYAT1,RAB28,ARHGEF4,ZNF337,GIT2,B3GAT3,RHOBTB1,DPH1,OPTN,SUGP2,DENND4A,ANKMY1,FHL1,TPK1,TXNL4A,GPR37,GUCY1B1,MAN1B1,JAK2,MID1,MPP2,TAGLN3,SLC11A2,PIK3R1,SMIM7,FSD1,MINDY2,PRPH,CNNM2,TRIM68,SUPT20H,STX1A,KIAA0930,TRIM2,TNS1,METTL3,XRCC4" Drug 4069_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "BBOX1,BEGAIN,GAS7,CDC14B,ARHGDIG,MYOM1,ADGRB2,BAIAP3,CALB2,SLC16A4,ENTPD2,NRXN3,SLC4A8,CSF1R,SEC14L5,SPOCK2,SPOCK3,EDN3,RASGRP2,CSPG5,OGA,GNAO1,LILRB4,GRM8,HLF,IRF8,LAMA2,MMP16,ADAM22,NF1,ENPP2,ACSS3,RGS4,SCN2B,HKDC1,ELMO2,HECW1,ATP10B,SYT5,TAL1,SENP7" Drug 4737_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "RALGAPA1,FZD9,SPARCL1,AMPD3,CDC42BPA,BAIAP3,CACNA2D1,SH2B1,SPOCK2,SPOCK3,VPS13B,ERCC2,IGSF6,GAD1,SIGLEC8,ALDH1L1,GPER1,TJAP1,KIFC3,SMAD1,MATK,MMP16,ADAM22,NFIX,SETD4,PDE4B,PFKFB2,PLCD1,ENOX1,RFX2,SUGCT,KLHDC8A,TCP11L1,KANSL3,SPART,CAMTA2,SYN2,PHF24,LAT2,PRDM10,TIGD6" Drug 6060_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,SEMA6A,CDC42BPA,SEMA7A,ARRB1,CFLAR,CACNA1I,LDLRAD4,CFAP410,CNTFR,CRY2,VCAN,GREB1,ARMCX2,ZNF804A,LYPD1,HIPK3,MBNL2,FER,FHL1,IQCG,PDLIM5,GLYR1,POLL,FERMT2,KCNH2,KCNN2,KPNA5,MIA2,KITLG,NLE1,PPP5C,PRKAB2,RNASEL,SEMA6D,SH3BP2,ASAP3,ELOVL4,PHLDB1,PLCB1,EXOC7" Drug 4305_UP Solasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "SYN3,APAF1,PPP4R4,PTCH2,ATP1A3,ADAM23,AZGP1,BMP7,CBS,NRXN3,CNR1,COL9A1,CSF1,CNTNAP2,HS3ST2,EDNRB,OLFM1,PRELID3A,SEPT9,SOX21,KCNQ3,SHC3,MYT1,NNAT,NOVA2,NPTX2,NTRK2,P2RX7,RETREG1,CEP41,PRKAR1B,RGS3,PNMA8A,PKNOX2,SNCA,IQSEC2,LMO3,TAL1,TNS1,TPM1,SLC17A7" Drug 6219_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASPHD1,AP2A2,AMH,NCOA1,CFLAR,LDLRAD4,CAMK2B,CAMK2G,AKAP12,TBC1D5,C2CD2L,TMCC2,DPH1,CNNM1,HSD17B14,IQGAP2,USP19,POLL,BTN2A1,RNFT2,HNMT,KCNH2,MATK,MBP,ZNF862,NF1,PLCD1,PLEC,PPP5C,MAPK3,PTCH1,ELOVL2,ZFP30,FERMT1,SNCA,ANKRD12,UBTF,REEP1,GDPD5,KCNAB1,ST7" Drug 5408_DN Ampicillin trihydrate [7177-48-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NME5,MADD,ALDH7A1,KYAT1,SLIT2,QKI,CRY2,SIPA1L1,DCAF8,MFAP3L,MED12,EGFR,FGFR1,BAIAP2,OGA,ERAP1,INPP5K,GNG4,GPER1,GRIK5,FICD,ELOVL5,HNMT,INPP5B,NF1,KCTD15,MINDY2,PTCH1,ELOVL2,GTDC1,RGS12,KIF13A,RBM34,SPATA7,TROVE2,THSD1,ST5,CEP68,CABIN1,RUNDC3B,SEMA3B" Drug 2269_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "RALGAPA1,SEMA6A,LTBP4,AMPD3,APBA2,APBB2,RASL11B,CFAP410,CA4,ARHGEF1,FOXN3,SLIT2,TPP1,CSNK1E,MFAP3L,RCAN1,CDKL3,VPS26C,FER,FAM49B,SRCAP,GLYR1,MSL3,GNG4,SLC2A6,JAK2,KCNN2,MSI1,ADAM22,ZNF862,MYT1,PLCD1,PRODH,PREX2,PEX26,PPP4R3A,KDM4C,PLCB1,UBTF,VAV1,WIPF1" Drug 2468_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "PPFIA3,KIF1A,BAIAP3,CFAP410,CALB2,CAMK2B,ARHGEF1,STOML1,SULT4A1,AKAP7,COL9A3,ABI3BP,CRMP1,CSF1,ARHGEF10,RIMS2,SPOCK2,EXOG,OPTN,RASGRP2,ERCC2,FGF12,FGFR1,GLYR1,GNAO1,GUCY1B1,IL12A,KIT,NNAT,NPTX2,NTRK2,PLCL1,CEP97,CCDC40,SNCA,SYT5,SLC19A3,CRTC1,RPRM,LMF1,KCNAB1" Drug 6010_UP Triamterene [396-01-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "C1QTNF3,APAF1,BAIAP3,CAMK2B,HIP1R,ING4,IGSF6,ZNF391,REEP2,FGF1,KHDRBS3,ALDH1L1,SRCAP,PCDH17,RUNDC3A,MAPT,AFDN,MMP17,ADAM22,MYCN,NNAT,RETREG1,PLCD1,POU6F1,CARF,GSTCD,SBF1,ZNF821,SLC2A5,KDM4C,PEG10,CDK19,ZBTB43,PLCB1,SMG6,WSCD1,DOCK9,PCDHA6,VGF,CLDND1,HPS4" Drug 2975_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,AMPD3,CASK,SLC4A4,ATP6V0A1,RCBTB2,PDE4DIP,PPP6R2,EGR3,ANKMY1,F8,FHL1,FLT1,ZNF44,INPP5K,SRCAP,ADAM28,TXNL4A,LPAR4,DIDO1,CACFD1,GSN,ZNF862,RETREG1,PLEC,PMP22,STRN3,MAPK3,RIPOR1,RPS6KA2,ATXN7,SH3BP2,FBXO11,SLC6A8,KDM4B,ZKSCAN5,FLRT2,BCL2L13,ATP6V0E2,REEP1,SENP7" Drug 6490_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APBB2,GAS7,RGS20,MARK4,N4BP2L1,ADAM15,HAP1,CAMK2G,COL9A3,DMPK,APC2,FGFR1,PRELID3A,SRCAP,GLI2,SOX21,HAS2,DHX35,C2orf72,MEF2C,NELL2,PLTP,PDZRN4,PPP5C,SAMD9,RASGRF1,GSTCD,ASAP3,PREX2,FAM214B,PKNOX2,COA1,SZT2,ZNF34,SLC44A1,CABIN1,ZKSCAN5,VGF,WIPF1,CLIP2,SLC30A3" Drug 2570_UP Methimazole [60-56-0]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,C1QTNF1,BEGAIN,PKP4,APBB2,PPFIA3,PPP4R4,ATP6V0A1,BACH1,CFAP410,CAMK2G,USP2,CLGN,CRY2,VCAN,PDE4DIP,RUBCN,ARHGAP32,EXOG,DTNA,PTK2B,SEC23B,IQCG,TMEM8B,GLYR1,GSN,IL12A,KCNN1,LSS,MAP4,OXTR,PDE4D,ENPP2,PTPRN2,ZNF821,KDM4B,IZUMO4,ARHGEF9,KIAA1107,LAT2,PHTF2" Drug 6700_DN Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "BIN1,APOC1,SEMA4G,ST3GAL5,ARHGEF7,SYNGR3,RAB26,IQCK,CREM,CNTNAP2,ARHGEF4,RHOBTB1,SGSM2,EZH1,AFF2,B4GALNT1,MSL3,GPR37,KCNN1,PALM,PDE4A,FA2H,POLG,MAPK7,GRAMD1C,WDR25,C1orf54,FBXW7,RPS6KA2,MAPK12,SEC14L1,AMBRA1,FNDC3A,TMCC1,THSD1,SZT2,DOCK9,TRIO,HIRA,TFIP11,KCNAB1" Drug 7292_UP Epirizole [18694-40-1]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADCY6,MTUS1,CDC14B,BCL7A,CFLAR,SCAPER,CBS,CBFA2T2,FOXN3,STOML1,PDE4DIP,CNTNAP2,CYBB,DAPK3,EGFR,IRAK4,ING4,RGS17,SPEG,IQCG,EFCAB2,CACFD1,ATXN2L,KHK,MIA2,ZNF862,LRRN3,MAPK7,RPS6KA2,ZFP30,SH3BP2,LIMS2,LIMCH1,ZHX3,TROVE2,THSD1,DNAH7,TIAM1,TK2,TNS1,TPM1" Drug 5403_UP Chlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADD2,LTBP4,CACNA1I,BAIAP3,CRYM,SEC14L5,DMPK,EDNRB,COQ7,RASGRP2,PIPOX,RRAGB,PTK2B,FGFR3,FHL1,KHDRBS3,TRAF3IP2,TMEM8B,SRCAP,STON1,PCLO,ADAMTS13,MAP4,MID1,PFKFB2,LRP12,POU6F1,CEP41,TCP11L1,SMARCD3,LIMCH1,ZHX3,SAMSN1,PLCB1,ARC,DMXL2,KIAA0930,PARD3,TRPM2,PDIA2,SLC30A4" Drug 2762_UP Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "KIAA1324,BEGAIN,SEMA7A,APC,SEMA4G,ST3GAL5,LDLRAD4,CA4,WHRN,SH2B1,RASSF2,DNAH9,DUSP9,EDNRA,PLXNC1,FHL1,IQGAP2,PCDH17,GPER1,IL6R,KCNB1,KCNH2,MAP4,TAGLN3,MX1,NNAT,MASP1,PTX3,C1orf54,ZNF493,ZDHHC14,RGS12,STUM,SH3BP2,PKNOX2,CXXC4,PEG10,DICER1,LAT2,XRCC4,HRASLS" Drug 7199_UP Ketotifen fumarate [34580-14-8]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APC,CASK,ADAM15,CFLAR,KSR1,LHX2,QKI,SLC4A8,PDE4DIP,FAM169A,GPRASP1,LYPD1,PARD6A,RCAN1,EDNRA,MBNL2,COQ7,RRAGB,F8,ACSL4,KAT8,AGAP2,EFCAB2,GCNT2,GLYR1,LIG4,PRPH,WDR25,ZFP30,PPP4R3A,RBM34,HECW1,SPTAN1,CLASP2,NXT2,KIAA0930,TRIM2,DICER1,PLPPR2,VIPR2,CLDND1" Drug 4718_DN Cefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APC,MARK4,SYNJ2,LHX2,PLAA,TPP1,COL4A5,ABI3BP,BAG4,BRINP1,RUSC2,AASS,HSD17B14,CDKL3,ST3GAL6,FHL1,GFER,GNG4,GRM8,IL6R,LMO2,MPP2,ADAM22,RETREG1,PPARA,SAMD9,PTN,RPS6KA2,ABLIM3,EPN2,SNCA,ZSWIM8,ARHGAP26,VPS13A,SMG6,TRIM2,FAM155A,VGF,VIPR2,KCNK12,XRCC4" Drug 6095_DN Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADCY6,NME5,C1QTNF3,ALCAM,BIN1,CDC42BPA,BCAS1,HAP1,CAMK2B,CBFA2T2,PLEKHB1,AKAP7,RCHY1,CREM,PDE4DIP,GIT2,JAKMIP2,SEMA4D,CGREF1,SEPT9,ALDH1L1,IPO5,LIG4,MAP4,MATK,MID1,ADAM22,PDE4B,PLXNB1,PRKAR1B,PRPH,CNNM2,PTN,SEMA6D,SNCA,KDM4C,EXOC7,PCDHA6,ZNF711,HPS4,SENP7" Drug 4249_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADORA2A,SEMA7A,GAS7,BMP7,SYNJ2,CALB2,HIP1R,CBLN1,FOXN3,SULT4A1,CNTN1,HAPLN1,CSF1,LRIG1,MFAP3L,DTNA,TNK2,EPHB1,PTK2B,DCTN2,NEU3,PCDH17,IL6ST,ITGA7,KIT,LAMA2,MMP16,NCAM2,NF1,NPR2,ACSS3,CCDC40,RET,KCNIP1,ST6GAL1,ZNF334,SOX15,ZHX3,TACR1,ZNF24,ZNF225" Drug 1501_UP Tolnaftate [2398-96-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AMPD3,BIN1,APBB2,SCAPER,CACNA2D2,SOCS6,COL4A5,CREM,ENTPD4,LRIG1,ZFYVE16,GIT2,LYPD1,RRAGB,ATP2C1,AHDC1,GLYR1,RAB30,TDRKH,GPR37,GRIK5,RNFT2,KCNH2,MBD1,MSI1,NEK1,SETD4,RETREG1,PRODH,PTCH1,SH3BP2,FBXO11,PPP4R3A,TACC1,IQCE,TRIM2,TPM1,CDK20,KCNAB1,MPPE1,ADAMTSL3" Drug 5771_DN Fluorometholone [426-13-1]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "MTUS1,KCNAB2,SEMA4G,MARCH3,NCOA1,SYNJ2,RAB28,NRG2,CPS1,CREM,CSF1R,VCAN,PDE4DIP,FAM169A,GIT2,DBT,SLC12A6,MBNL2,TNK2,STX2,F8,MSL3,BTN2A1,RNFT2,GUCY1B1,HSF2,ZNF862,NEK1,NF1,MINDY2,PTPRN2,FAM184A,RGS4,AMBRA1,BTBD7,KDM4C,SSBP2,ZKSCAN5,HIRA,PLPPR2,MPPE1" Drug 2244_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,SEMA6A,APC,CDK10,SEMA4G,MARK4,CFLAR,GYG2,HAP1,ARHGEF2,ARHGAP33,SLIT2,PICK1,CRY2,CSF1,DZIP3,RIMS2,TBC1D5,DAPK3,EGFR,RRAGB,KAT8,FGFR1,FAM49B,PRELID3A,INPP5K,MALT1,RAB30,GNG4,SPACA9,GSTM5,IL6ST,MAP4,NF1,RGS12,FBXW7,ZNF821,SUPT20H,PPP4R3A,PLCB1,TK2" Drug 2515_UP Hexestrol [84-16-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AGT,ALK,LGR5,SEMA4G,PRX,PROM1,KALRN,CAMK2B,CLGN,CNTFR,FAM149A,COL9A3,CREM,EXOG,TNK2,AFF2,GATM,GNAL,GNG4,KCNJ5,L1CAM,MPP2,MTRF1L,PPARA,DCHS2,CNTLN,RNASE1,ZFHX4,EMID1,CNKSR2,ABLIM3,LIMS2,PEG10,CLSTN2,PHLDB1,ASTN2,TBCEL,WSCD1,VSNL1,SEMA3B,KCNAB1" Drug 6380_UP STOCK1N-35215; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADRA1D,AMPH,SEMA7A,ALDH7A1,ADAM23,ADGRB2,CALB2,CBS,MAGI1,RAB33A,LYPD1,AGAP2,DCTN2,NSG1,OGA,DISC1,ALDH1L1,SRCAP,ATXN2L,ICA1,IL6R,INPP5B,KCNF1,KCNJ5,MAP2,MAPT,NTRK2,PCDH9,MBOAT7,PTN,FBXW7,TCP11L1,SLC6A11,SLC9A5,SNAP25,HECW1,KIAA1107,SLC44A1,TNS1,TPM1,NAV3" Drug 7026_DN Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABR,CDC14B,NUMB,EIF4G3,SYNJ2,CAMK2G,LHX2,HOMER3,ARMC8,COL4A5,C2CD2,CREM,KIAA0586,GIT2,FBXL5,MAMLD1,EIF5,STX2,POLR1B,TRMO,PDLIM5,ATP2C1,CGREF1,INPP5K,MSL3,GRB10,RNFT2,MAP4,RETREG1,STRN3,PRKAR1B,PTPN13,ZCWPW1,CAMTA2,CEP68,HIRA,UBTF,LMF1,CLDND1,SPHK2,RNF170" Drug 2481_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APBB2,ADAM23,BACH1,SCAPER,CD86,QKI,IQCK,RCHY1,RUSC2,DTNA,FCF1,ST3GAL6,FHL1,GALC,ARFIP1,LILRA2,PADI2,MAP4,NF1,NFYA,MINDY2,MAPK7,SAMD9,PTK2,C12orf49,RASA3,FAM102A,NUBPL,PPP4R3A,CCDC88A,SPTAN1,TSPYL2,SS18,NXT2,ZEB1,ICAM5,PARD3,PIK3R5,LMF1,LAT2,SENP7" Drug 3818_DN U-62066 [87151-85-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASPHD1,BEGAIN,AMT,SEMA7A,SEMA4G,PPP4R4,NRP2,BMP7,MTMR3,CBS,ARHGAP33,LARGE1,AKAP7,AKAP5,SH2B1,HAPLN1,CSF1,SPOCK3,SUGP2,NCALD,EZH1,KCNMB4,ICA1,TAGLN3,PDE4B,POLG,WDR25,GSTCD,RPS6KA2,PREX2,BTBD7,SNCA,ARHGAP26,SPTB,CABIN1,TNS1,TRIO,FLRT2,ZNF225,DPF3,GAN" Drug 2117_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABR,ADCY6,NME5,BIN1,OGT,EP400,ATP2A2,KIF1A,MTMR2,HIP1R,KRIT1,SCARB1,RAB28,TPP1,ARMC8,PDE4DIP,CNTNAP2,ARHGAP24,CDON,EDIL3,ANKMY1,GAA,GPER1,HNMT,IL6ST,INPP5B,NFYA,PRKAR1B,MAPK7,SH3TC2,GAL3ST4,RGS4,SCN8A,ASAP3,KDM4B,FNBP1,IQSEC2,ZBTB43,COBL,TRIM2,ZKSCAN5" Drug 483_DN Gleevec; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "KDM5D,NDRG2,MTUS1,KCNAB2,PDE8B,MPDZ,BMPR1B,CACNA1I,CA12,CD86,NDST3,LHX2,SH2B1,PDE4DIP,KLHL3,RCAN2,CORO2B,FCGRT,VSIG4,IRF8,MAN2A2,MGAT3,MYO6,PFKFB4,PLXNB1,C19orf57,PTPRD,PTPRN2,MARCH1,RET,ZNF671,ASAP3,EXOC7,TNS2,CRTC1,ZMAT3,ZNF142,MAP3K12,GDPD5,SLC17A7,MPPE1" Drug 3350_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,AP2A2,NME5,APBA2,GAS7,FAM131A,SLC2A11,CFAP410,RUNX1T1,CBFA2T2,COL9A3,KLHL3,MBNL2,ERCC2,ZNF589,FGF12,EFCAB2,CPLX2,SRCAP,PCDH17,GPER1,TJAP1,KCNQ3,SMAD1,MYT1,PCDH9,CDK18,PLTP,CNTLN,ZSCAN32,TRIM68,KCNIP1,SMPD3,SH3BP2,ASAP3,SMARCD3,LIMCH1,ARHGAP26,RBM26,GPR161,SPHK2" Drug 5692_UP Josamycin [16846-24-5]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADORA2A,CDK13,MARK4,CFAP410,CAMK2B,CHRNA4,SLIT2,LHX2,MAML1,C2CD2L,SPOCK3,MRNIP,ZNF589,HPCAL4,FOXF2,DCTN2,OGA,GAD1,SRCAP,TDRKH,SOX21,TJAP1,MAP4,P2RY1,PDE4D,TMOD2,PFKFB2,LRP12,PPP1R1A,ELOVL2,PTN,ENOX1,ZNF821,SH3BP2,SLC11A1,PEG10,PLCB1,TAL1,SYNE1,CRTC1,MKRN3" Drug 5244_DN Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "BIN1,APOC1,DNAH17,SLC4A4,GYG2,CA12,SH2B1,ARHGEF4,RASSF2,TSPAN5,MBNL2,MRNIP,NCALD,ZNF589,BAIAP2,PDLIM5,RAB30,ICA1,INPP1,KITLG,ADAM22,MBOAT7,TMEM104,RGS12,ZFHX4,SLC6A8,SLC9A5,LIMCH1,SNCA,ZHX3,ZC3H13,TROVE2,PHLDB1,RPGRIP1L,CRTC1,TK2,PARD3,KAT6B,KLC2,MAP3K12,SEMA3B" Drug 5785_DN Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADCY6,MTUS1,BIN1,AMT,CHN2,HAPLN1,CSF1,CSF1R,PHF14,ARHGEF4,PPP6R2,DCAF4,SPOCK3,DPH1,HIPK3,DENND4A,ERAP1,PCDH17,SHISAL1,KIF2A,MATN3,NF1,NPR2,NLE1,MAPK7,RIPOR1,SH3TC2,ZNF671,ATXN2,FBXO11,ANKRD6,PEX26,COBL,MCF2L,SZT2,CHST8,PARD3,TNS1,HIRA,LMF1,WIPF1" Drug 1530_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABHD6,SEMA6A,ALCAM,TRMT9B,APBB2,APC,APOC1,MARK4,EIF4G3,SYNJ2,CFAP410,SEPT7,HOMER3,AKAP7,ENTPD4,NCOR1,DGKG,GIT2,EIF4G2,NCALD,FGF13,FGFR1,DCTN2,PDLIM5,MSL3,NXPH3,IL6ST,MBD1,MN1,NNAT,SLC25A23,ZSCAN2,ZFHX4,RPS6KA2,NLGN1,SLC2A5,SPART,DIP2A,SLC44A1,HIRA,EPM2A" Drug 7069_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "BIN1,CDC42BPA,SHROOM2,ATP2A2,ADAM15,CNOT8,PLAA,CRY2,PDE4DIP,SLITRK5,ARHGAP32,B3GAT3,PARD6A,SGSM2,ERCC2,SEMA4D,SRCAP,KCNJ5,KPNA5,L1CAM,LIG4,NF1,NFYA,KCTD15,ZNF426,GRAMD1C,BCAS3,RGS3,MCMBP,SUPT20H,DZIP1,BTBD7,SEPT8,ARHGEF9,SZT2,SYNE1,SSBP2,FAM155A,ZNF24,HPS4,UBE3B" Drug 6805_UP Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "FZD9,AGT,GAS7,SLC4A4,ALDH7A1,ADAM23,SCAPER,CACNA1I,CACNA1A,CAMK2B,CD86,CLGN,SULT4A1,FAM149A,WHRN,CPS1,VCAN,PDE4DIP,ELMO1,CDON,ECM2,OLFM1,ZNF44,GAD1,PCDH17,GNAL,GNAO1,ELOVL5,PRKAR1B,MAPK10,PTX3,CRTAC1,RASA3,FAM214B,CCDC88A,PHLDB1,PLCB1,SZT2,TPM2,UCHL1,VIPR2" Drug 3836_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADRA1D,CDC14B,BAIAP3,SRSF11,PLAA,CSF1,HDAC4,HSD17B14,ANKMY1,SEMA4D,CINP,MSL3,STON1,SLC2A6,HNMT,IL6R,ADAM22,NF1,CNOT4,NPTX1,NTRK2,PFKFB2,NLE1,ZMAT4,CCDC25,NEK11,EMID1,SH3BP2,ASAP3,FAM214B,ZKSCAN3,SMARCD3,THSD1,NSFL1C,VPS13A,CABIN1,VIPR2,LAT2,KCNK12,ZNF45,REEP1" Drug 3471_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADORA2A,C1QTNF3,LTBP4,KCNAB2,APOC1,ALDH7A1,CFLAR,CA4,CAMK2G,ARHGAP33,CLGN,CACNA2D2,SRSF11,ENTPD4,CSF1,MAML1,SPOCK2,DTNA,C3orf18,HPCAL4,ERAP1,GRM2,ICA1,KCNF1,TM6SF1,MGAT3,MSI1,ZNF862,PLXNB1,MAPK7,TCP11L1,SH3BP2,KDM4C,PLCB1,ARC,KIAA0930,DOCK9,CRTC1,TRIO,REEP1,EMSY" Drug 3722_DN Tropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASIC1,ALK,APBB2,CDC14B,ALDH7A1,CACNA1A,AP4M1,LARGE1,B4GALT6,QKI,AKAP7,NRG2,CPS1,VCAN,SPOCK3,DTNA,HIPK3,EIF4G2,COQ7,ETV1,ZNF589,OGA,DISC1,ARFIP1,INPP5B,JAK2,CNOT4,PCDH9,PIK3R1,PTCH1,FNDC3A,PPP4R3A,KDM4B,SS18,NXT2,TMPO,TRIO,VLDLR,ZNF24,SEMA3B,SENP7" Drug 3090_UP Altretamine [654-05-6]; Up 200; 19uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABHD6,ADCY6,MTUS1,KCNAB2,BCAS1,CASK,ARRB1,CACNA1I,SLC16A4,SEPT7,STOML1,CNN3,CREM,CRMP1,ABCG1,C3orf18,EPB41,STX2,ETV1,EYA1,PTK2B,DCTN2,ERAP1,POLL,SPACA9,PRDM5,KCNF1,MAP4,MBNL1,MSI1,CNOT4,PDE1C,MTRF1L,ZSCAN32,ZMAT4,ST6GAL1,TBCEL,PCDHGA10,TNS1,GDPD5,KCNAB1" Drug 6787_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,AK2,PPFIA3,SYNGR3,PLAA,CLCN3,TPP1,BAG4,ARHGEF10,GPRASP1,DCAF8,KIAA0586,MAML1,MFAP3L,OPTN,CDKL3,ANKMY1,EZH1,OGA,SRCAP,GPR37,MUM1,MPP2,NNAT,PCDH9,NLE1,WDR25,RAD51D,ZCWPW1,ERC1,SPART,ARC,TBL1X,TRIM2,AP4E1,PARD3,KLC2,GDPD5,SEMA3B,AAAS,GAN" Drug 1947_UP Hesperetin [520-33-2]; Up 200; 13.2uM; PC3; HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,ADORA1,APOC1,CA12,CBR1,KRIT1,P2RX6,TBRG4,CRY2,OSBPL3,FAM169A,GIT2,RUSC2,MED12,DPYSL2,DTNA,E2F5,EPB41L2,ERCC2,CINP,PDLIM5,DENND2A,SPIN1,GPER1,GSN,SLC2A6,KIF5A,PLCD1,ZNF426,CNNM2,ZNF821,GALNT10,AMBRA1,KBTBD4,TSPYL2,HEY1,PARD3,LMF1,WNT7A,UPF3A,ITM2C" Drug 6471_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,APC,GAS7,PDE8B,SLC4A4,ALDH7A1,ATP6V0A1,SCAPER,SGCE,SOCS6,WHRN,PDE4DIP,DAPK1,HS3ST2,TENM1,ENO2,FGFR1,ANKFY1,FYN,ERAP1,GRM8,KIF5A,LIG4,MBD1,ADAM22,NOVA2,SLC25A23,MAPK7,ZSCAN2,NUDT11,TCP11L1,ASAP3,ANKRD6,ATP10B,TAL1,SLC35G2,CLIP2,NDRG4,SLC30A3,EPM2A,JPH3" Drug 6313_DN "Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "C1QTNF1,MPDZ,CFLAR,CCNT1,BAG4,ZFYVE16,ZNF337,DBT,SPOCK3,FEM1B,OPTN,F8,FGFR1,FYN,INPP5K,CRCP,IPO5,MEIS1,MMP16,MN1,SETD4,PCDH9,PIK3R1,CNNM2,BCAS3,ZSCAN32,PTPN13,SH3TC2,RBBP6,SAFB,SMARCC2,ARHGAP26,ZBTB43,ELOVL4,MLST8,TRIM2,TNS1,HIRA,LMF1,ZNF45,PLSCR4" Drug 3558_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "PPFIA4,EPB41L5,MARK4,ATP6V0A1,SCAPER,BAIAP3,CFAP410,CAMK2B,USP2,CHRNA4,QKI,ARHGEF6,WHRN,MYRIP,SNCAIP,VCAN,CNTNAP2,RASSF2,STX2,OLFM1,HPCAL4,CSPG5,TMEM8B,SRCAP,HLF,SMAD1,MAN2A2,MYCN,CNOT4,NECAB2,C19orf57,RASGRF1,ZFP2,SNCA,KIF13A,ZC4H2,ICAM5,TPM2,AMACR,PDIA2,ZFP37" Drug 3062_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "LGR5,CACNA1G,USP2,SLC16A4,LARGE1,SOCS6,AKAP6,NRG2,CRYBB1,PDE4DIP,BRINP1,EDN1,AASS,EPB41,ZNF549,BAIAP2,GNAL,HNMT,SCIN,MAPT,MATN2,MYT1,PCSK5,SEPT4,PPP2R2B,PTPRB,NUDT11,ST8SIA1,SLC11A1,ATP10B,TBCEL,TIAM1,RIMBP2,TRIO,TRO,LMF1,VSNL1,KLC2,KCNK12,MAP3K12,DNALI1" Drug 4622_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AMT,PPFIA4,KRIT1,PLEKHB1,B4GALT6,RAB28,ABCG2,IQCK,BAG4,CNTNAP2,PPP6R2,DCAF4,BRINP1,DTNB,FAM13A,MRNIP,RGS17,STX2,GLYR1,GNAL,INPP5B,PLXNB1,GRAMD1C,PRPH,CNTLN,PTPRB,FBXW7,ZFP30,ASAP3,SLA,PEX26,SPTAN1,ST5,JMJD6,PLCB1,EXOC7,TPM2,AMACR,MAP3K12,EMSY,HPS4" Drug 5883_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "GAS7,SYNJ1,MYRF,HAP1,RCBTB2,CSF1R,PDE4DIP,ARHGAP24,TOM1,CNNM1,MBNL2,ING4,RGS17,PIPOX,DLC1,SEPT9,GNAO1,GPR37,KCNJ5,KPNA5,MIA2,CNOT4,PRKAR1B,MAPK7,PNMA8A,ZNF671,MAPK12,ASAP3,SLC11A1,SMARCD3,SAMSN1,COBL,ASTN2,KLHL4,PCDHA5,TMEM121,UGT8,LAT2,NT5M,KCNAB1,DPF3" Drug 5863_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ACTN1,AGT,BIN1,APC,GAS7,BMP7,CACNA1G,SULT4A1,RAB26,GPRASP1,HDAC4,MFAP3L,DNAH9,CNNM1,HSD17B14,BAIAP2,SCARA3,DCTN2,FYB1,GLI2,STON1,GPR37,SOX21,SCIN,MT1M,MX1,NTRK2,PDE4B,ENPP2,SAMD9,PTPRE,NEK11,MAPK12,CCDC88A,BTBD7,ATP10B,COBL,KIAA1107,TMEM121,HPS4,KCNAB1" Drug 6867_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "KIAA1324,C1QTNF3,APOC1,CDK10,RGS11,NRP2,SCAPER,FOXN3,NRXN3,CNTFR,AKAP7,AATK,CTH,ZFYVE16,ACOT8,ETV1,AFF2,COPS8,TDRKH,ATXN2L,L1CAM,NPR2,CLDN11,PFKFB2,PIK3R1,TMEM231,CCDC40,NEK11,ZNF671,RPS6KA2,STUM,SH3BGR,KDM4D,ZNF667,KIF13A,IZUMO4,KDM4C,MCF2L,TIAM1,CDK20,UGT8" Drug 3829_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASPHD1,APC,SLC4A4,BCL7A,CAMK2G,CRLF1,FAM189A2,CSF1,MAML1,ZNF804A,MFAP3L,DTNA,DUSP9,CNNM1,ELN,GFER,POLL,RNFT2,HNMT,ITPKB,KHK,NPR2,SLC25A23,SMIM7,STRN3,MBOAT7,PTPRE,ZSCAN2,RGS12,SBF1,SEC14L1,SLC6A8,SMARCD3,DOP1A,ZNF34,TK2,TPM1,FAM155A,LMF1,SEMA3B,FIP1L1" Drug 6369_DN CGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "TRMT9B,BMPR1B,SYNJ1,FUBP1,CACNA1I,HAP1,QKI,CNR1,IQCK,SH2B1,PDE4DIP,RIPOR2,DCAF8,MFAP3L,CDON,EDIL3,EGFR,MBNL2,DCTN2,FYB1,GPD2,LILRA2,GPER1,HSF2,LIG4,LSS,MATK,ADAM22,OPRL1,PALM,RGS4,STUM,FNDC3A,RBM34,DOK5,ZSWIM8,SPTB,SYN2,PIK3R5,TRO,UBE3A" Drug 6952_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "SEMA6A,APBB2,CFLAR,KSR1,ST3GAL5,SCARB1,LRRFIP1,AKAP7,PDE4DIP,GREB1,ARMCX2,SPOCK3,DMPK,OPTN,SUGP2,EGR3,FECH,FGF12,TJAP1,MIA2,PFKFB3,PLTP,SNRK,PTN,MAPK12,FRMPD1,KDM4B,ZHX3,ARHGAP26,SS18,NSFL1C,ARHGEF9,ASTN2,WSCD1,TRIM2,CRTC1,TK2,VGF,HPS4,SEMA3B,PLSCR4" Drug 1508_DN Glipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,GAS7,CFLAR,CAMK2G,QKI,PICK1,SH2B1,DAPK3,GIT2,SLC12A6,DTNA,TSPAN5,HIPK3,SUGP2,FER,FAM49B,OGA,ERAP1,AHDC1,KCNMB4,CACFD1,ATXN2L,MBD1,CNOT4,POLG,MINDY2,PRKAR1B,TCP11L1,PEX26,EPN2,SMARCD3,LIMCH1,IQSEC2,AP4E1,HIRA,PLPPR2,VIPR2,XRCC4,SPHK2,EMSY,KCNAB1" Drug 6054_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AGT,AMPD3,APBA2,MARK4,RASL11B,ATP2B2,ADGRB3,CACNA1G,CBARP,ARHGEF6,PICK1,AKAP7,WHRN,COL9A3,HAPLN1,RGS6,PDE4DIP,DPP6,EDN3,EDNRA,ZNF589,FGF1,FGFR1,FHL1,GPER1,GRM8,HLF,TJAP1,KIFC3,MYO7A,NPTX1,P2RY1,PGAM2,PURG,ST6GAL1,SLA,DOK5,HECW1,SMG6,TPM1,PARP11" Drug 4976_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASIC1,NDRG2,NME5,LTBP4,APC,PPFIA3,SEMA4G,CDK13,LDB2,CBFA2T2,ARHGAP33,CHRNA4,HOMER3,CSF1,CTH,RIMS2,EXOG,FGF13,GLYR1,GPER1,KCNN1,MYO9A,CNOT4,P2RY1,SERPINI1,RETREG1,MINDY2,CEP41,PTPRO,ZNF493,ZFHX4,SLC11A1,DOP1A,ST5,ARHGEF9,PARD3,PIK3R5,KLC2,SLC17A7,KCNAB1,PHTF2" Drug 3123_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "SPARCL1,CDC42BPA,AQP6,RASL11B,MPDZ,BMP7,CACNB4,CAMK2B,CAPN3,COL9A3,SH2B1,CRYM,USP6NL,SNPH,DAPK3,TMCC2,RCAN2,LRRC17,MTSS1L,ANKMY1,OLFM1,INPP5K,CPLX2,ALDH1L1,GRIK5,AFDN,NTRK2,PDE1C,CEP41,RELN,RGS12,TCP11L1,SEMA6D,CDK19,RBM26,ATP10B,PLCB1,CRTC1,ICAM5,TNS1,VSNL1" Drug 1371_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "WASF1,KRIT1,SRSF11,CNOT8,SOCS5,APPL1,ARHGAP32,DCAF8,EGR3,VPS26C,ACSL4,SEC23B,ERAP1,SRCAP,IRAK3,KTN1,NFE2L2,GPSM2,PPM1B,RBBP6,MSANTD2,CLIP1,ATXN7,HSPA4L,KBTBD4,SMARCC2,GLT8D1,SPART,TROVE2,LARP4,KLHL7,ANKRD12,FAM208A,ATMIN,TCF4,TMPO,TNS1,WIPF1,ZNF189,EVI5,VPS35L" Drug 6009_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NME5,LTBP4,APBB2,MARK4,ATP2B2,CFLAR,BAIAP3,CBFA2T2,CDH2,TAOK2,SLIT2,ARHGEF6,CNTFR,WHRN,RCHY1,NECTIN3,NCOR2,GREB1,ARHGAP24,GIT2,TMCC2,C3orf18,POLL,PRRC2B,PCDH9,RETREG1,PPARA,KCTD17,KLHDC8A,ZNF821,FBXO11,PPP4R3A,SLC22A4,LIMCH1,KIF13A,ARC,KIAA0930,TNS2,CRTC1,AP4E1,LAT2" Drug 2734_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "MTUS1,APAF1,CASK,ATP6V0A1,CFLAR,SYNJ1,FUBP1,CFAP410,CLGN,TAOK2,QKI,CREM,DGKG,DBT,KIAA0753,CELSR3,COQ7,ZNF589,FHL1,CELF1,INPP5K,LILRA2,PADI2,LIG4,MAP4,MIA2,NFYA,PDE4A,PLTP,POU6F1,MINDY2,PTCH1,TMEM231,RGS3,CARF,FBXW7,TBL1X,UBTF,CLIP2,ZNF225,EMSY" Drug 4363_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "SEMA6A,BIN1,APBA2,PPFIA3,EIF4G3,ATP6V0A1,SCAPER,CAMK2G,KRIT1,ARHGAP33,FOXN3,PLEKHB1,CLCN3,DNM1,DTNA,ERCC2,NCALD,FGFR1,PRKAG2,RAB30,STON1,INPP5B,ITPKB,KCNN2,IPO5,LAMP2,MBNL1,LRP12,PPP5C,PRKAR1B,C1orf109,ZDHHC14,RGS12,ZFHX4,SEC14L1,SH3BP2,ZBTB43,PHLDB1,TRIM2,SIK3,TPM1" Drug 5353_UP Fusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,AK2,LTBP4,APC,APOC1,MTMR2,CACNA1I,CA4,VAX2,CRY2,PDE4DIP,CDON,FEM1B,SRCAP,GLYR1,GNAO1,PCLO,SOX21,HNMT,LSS,MAN2A2,MAPT,ZNF862,NEK1,PLEC,POLG,CNNM2,TMEM104,TCP11L1,SH3BP2,SLC9A5,LIMCH1,RBM34,STX1A,TRIM2,PCDHA6,ZNF34,THRA,UBE2H,GDPD5,MPPE1" Drug 5285_UP Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG3,AP2A2,C1QTNF3,LTBP4,DOC2A,SYNJ2,C5,CFAP410,ARHGAP33,B4GALT6,VAX2,SLC4A8,SOCS5,PDE4DIP,SUGP2,EGFR,VPS13B,COQ7,STX2,NCALD,ANKMY1,BAIAP2,AGAP2,OGA,POLL,DIDO1,NF1,NFYA,LRP12,NKAIN1,GTDC1,ABLIM3,ZNF430,BTBD7,LIMCH1,SPTAN1,NXT2,CEP68,TBL1X,TRIM2,PLPPR2" Drug 5506_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ABR,CDC42BPA,APBA2,DDO,PLA2G4C,CNTNAP2,RIMS2,ELN,ETV1,FER,FUT9,RUNDC3A,ADAMTS13,IPO5,MAN2A2,MBD1,NEFM,NF1,GPR85,STRN3,PILRA,LRRN3,PTCH1,ELOVL2,ZNF493,RGS12,NEK11,RPS6KA2,CPEB3,SLA,ZKSCAN3,COA1,FAIM2,ZNF415,PEG10,CRTC1,SLC35G2,WBP2,LAT2,XRCC4,ZNF24" Drug 2404_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASPHD1,CDC42BPA,PRX,ARRB1,CDO1,DLGAP1,HOMER3,CPS1,CRMP1,CSF1R,PPP1R16B,RIMS2,JAKMIP2,DNAH9,DTNA,MRNIP,EIF1,RASGRP2,CDKL3,DLC1,OLFM1,GFER,GLYR1,PRUNE2,CACFD1,GRM8,PPARA,FBXW7,CCDC92,NLGN1,ARHGEF40,CLSTN2,THSD1,SS18,PDLIM2,CRTC1,TIAM1,AMACR,FLRT2,PLSCR4,GAN" Drug 4078_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "AP2A2,ZSCAN18,ATP2B2,BCHE,FUBP1,MTMR3,CACNA2D1,HAP1,RUNX1T1,SCARB1,CACNA2D2,RAB33A,PLAA,TPP1,SULT4A1,PICK1,HAPLN1,RGS6,RIPOR2,SPOCK2,SPOCK3,EDIL3,EDNRA,MRNIP,PIPOX,AGAP2,IQGAP2,IL6R,KCNN1,NF1,PDE4B,RNASEL,STK32B,EMID1,ZNF821,ASAP3,SLC2A5,IZUMO4,RBM26,NPL,SPHK2" Drug 4702_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASIC1,NDRG2,SEMA6A,GAS7,PDE8B,ATP1A3,CACNA2D2,NRXN3,QKI,HAPLN1,SEC14L5,FAM13A,MBNL2,SRPK3,AFF2,ZNF44,GCNT2,CSDC2,GPR37,PCLO,INPP1,KCNN1,MID1,AFDN,NF1,MAPK10,MARCH1,ZMAT4,TRIM68,ZFHX4,SCN2B,MRAS,ASAP3,ARHGEF40,ZKSCAN3,IQSEC2,DOCK9,LAT2,WNT7A,PLSCR4,FAM13C" Drug 4063_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ARHGDIG,CDK13,ADGRB2,ADGRB3,FUBP1,KALRN,CAMK2B,RUNX1T1,TAOK2,COL9A3,RIMS2,SEC14L5,C2CD2L,EBI3,ING4,EPHB1,IGSF6,SIGLEC8,GNAO1,PRUNE2,TPPP,HNMT,LAMA2,LSS,MAN2A2,AFDN,OGG1,PLCD1,PTPRN2,ACSS3,CCDC40,KCTD17,SLA,SNAP25,SPTB,PLCB1,SYT5,SMG6,HIF3A,SLC30A3,KCNAB1" Drug 5087_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADRA1D,KCNAB2,STX16,CACNA1A,ARHGEF4,DAPK3,EDIL3,HIPK3,FCF1,ETV1,SCML2,ANKFY1,DLL3,GPD2,HNMT,AGFG1,DHX35,HSF2,SCIN,INPP5B,KCNN1,NDP,CNOT4,STRN3,MAPK7,KLK6,SH3BGR,ZFP30,SNCA,TMCC1,PEG10,SS18,TCF4,OSBP2,WIPF1,ZNF74,ZNF225,EVI5,MPPE1,PHTF2,RNF170" Drug 543_UP "1,5-Isoquinolinediol; Up 200; 100uM; HL60; HG-U133A" Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NDRG2,AP2A2,ANK2,APBB2,CDK10,RASL11B,N4BP2L1,ST3GAL5,KYAT1,FOXN3,CHN2,FAM189A2,TMEM184B,CRMP1,RIMS2,SPOCK2,C2CD2L,DTNA,ING4,IGSF6,ZNF589,BAIAP2,FYN,CACFD1,PRDM5,NXPH3,JAK2,MBD1,CEP41,PRPH,GAL3ST4,TRIM68,RGS12,STUM,SH3BP2,TSNAXIP1,ZSWIM8,CDK19,RNF103,KCNAB1,DPF3" Drug 6842_DN Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ALCAM,AMPD3,MARK4,EIF4G3,CFLAR,SYNJ2,CACNA2D2,CRY2,CSNK1E,RIMS2,KIAA0586,CNNM1,ING4,KAT8,ZNF589,FGFR1,PDLIM5,GFER,POLL,CNTRL,ADAMTS13,GSN,ATXN2L,KCNH2,MAPT,NPR2,PCBP3,RETREG1,CEP97,SH3BP2,COA1,SNCA,KDM4C,SAMSN1,PLCB1,TMEM121,VGF,LMF1,ZNF189,EMSY,SMIM8" Drug 6265_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NME5,C1QTNF1,BIN1,AMT,APBB2,ALDH7A1,CFLAR,EPS15L1,FAM169A,TBC1D5,JAKMIP2,RCAN1,EDNRA,MTSS1L,STX2,FGFR1,GNAO1,SLC2A6,MGAT3,MID1,MSI1,NEFM,NF1,PLXNB1,ELOVL2,RPS6KA2,EMID1,FBXO11,SYBU,EPN2,ZSWIM8,CAMTA2,PHLDB1,MCF2L,KIAA0930,SLC44A1,PLPPR2,LMF1,WRN,NT5M,SEMA3B" Drug 3996_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "PPFIA4,DDO,SLC4A4,ADGRB2,BMP7,SYNJ1,BAIAP3,CACNB4,CALB2,CAPN3,TPP1,CNTFR,IQCK,CABP1,AKAP5,NCOR2,CSF1,CSF1R,PDE4DIP,CNTNAP2,SPOCK2,SGSM2,AGAP2,FYB1,ITGA7,KCNJ5,KCNN1,PACRG,MSR1,NF1,PALM,POU6F1,GDPD2,RASGRF1,RGS4,FUZ,PKNOX2,SP2,RIMBP2,TRO,DNALI1" Drug 3865_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "RALGAPA1,CDC42BPA,APC,MARK4,GYG2,TAOK2,TPP1,SH2B1,CSF1,SIPA1L1,DTNA,HIPK3,EIF4G1,HSD17B14,ENO2,FGFR1,FHL1,CGREF1,SYT17,SRCAP,GLYR1,GPD2,LSS,ADAM22,NEK1,NPR2,PPP5C,ENOX1,RGS12,CCDC25,ASAP3,CDK19,PLCB1,EXOC7,KIAA0930,TRIM2,TRIO,LAT2,KCNK12,PHTF2,RNF146" Drug 4501_DN Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADD1,AMT,SEMA4G,MARK4,SLC4A4,CACNA2D2,LY86,PICK1,CSF1R,DAPK3,EGFR,HSD17B14,FGFR1,FYB1,SEPT9,SRCAP,GLYR1,IL6ST,KCNJ5,LSS,ADAM22,LYRM9,ZNF862,NF1,MAPK7,PTCH1,GSTCD,TCP11L1,SH3BP2,AMBRA1,SLC4A3,SLC9A5,SLC14A1,ZNF667,KDM4B,CEP68,COBL,SMUG1,RPRM,NT5M,SEMA3B" Drug 6864_UP STOCK1N-28457; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "APBB2,CDK13,CACNA2D2,EPS15L1,IQCK,NCOR2,ABCG1,RCAN1,SNX29,ING4,TNK2,CORO2B,ALDH1L1,POLL,JAK2,KIT,MX1,NF1,NFYA,NTRK3,DUSP26,NLE1,FSD1,PPP2R2B,MAPK7,WDR25,C1orf54,PEX26,PPP4R3A,SLC11A1,BTBD7,CDK5RAP2,SNCA,ZNF415,DDN,SYNE1,TMEM121,BEX4,RIMBP2,LMF1,XRCC4" Drug 341_UP sodium 4-phenylbutyrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ASIC1,OSBPL1A,DOC2A,AMPD3,CDC42BPA,GAS7,AZGP1,RAB29,KALRN,ARHGEF2,ZMYM4,SOCS6,CNTFR,C2CD2L,HIPK3,FEM1B,OPTN,MBNL2,BAIAP2,SEC23B,FAM49B,ZNF638,LUZP2,IPO5,NACA,NF1,OPRL1,MAPK10,RMI1,ZNF821,SH3BP2,SLA,ELMO2,KDM4B,ZSWIM8,ZBTB43,ANKRD12,EXOC7,SIRT1,ZKSCAN5,MPPE1" Drug 6327_DN Nabumetone [42924-53-8]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "CFLAR,CA12,SLC25A14,SPAG9,NFS1,QKI,HOMER3,HAPLN1,SGSM2,ING4,COQ7,ST3GAL6,FCGRT,FECH,FHL1,CINP,CAMKK2,TRAF3IP2,DISC1,GPD2,MAP4K5,MAN1B1,FAM69A,GIT1,MYO6,SUGCT,ALG9,CCDC25,ATXN2,FUZ,LIMS2,NXT2,FBXW11,TRIM2,PARD3,TPM1,ZKSCAN5,WNT7A,MAP3K12,FZD3,KAT6A" Drug 2718_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "NME5,PLA2G4C,MARK4,SLC4A4,RGS11,BMP7,CA12,STOML1,FHL5,NCOR2,DAPK3,SV2B,CDON,EDN3,PLXNC1,RASGRP2,SCARA3,PRELID3A,SEPT9,NEU3,ALDH1L1,GFER,KCNN1,KIFC3,MGAT3,MN1,ADAM22,FXYD7,FXYD1,LRRN3,KLK6,WDR25,SEMA6D,FRMPD1,SLC11A1,PLCB1,SYT1,SYT5,UBE3A,LMF1,FAM13C" Drug 5843_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "ADGRF5,APBB2,SEMA4G,ATP2B2,BAIAP3,SEPT7,HAPLN1,NCOR1,PDE4DIP,DCAF8,GIT2,TUBD1,KAT8,ERAP1,MSL3,GNAO1,GPD2,GPER1,GRIK5,MAPT,MIA2,TAGLN3,MX1,CNOT4,NTRK2,NLE1,GSTCD,KCNIP1,TRAPPC13,MRAS,SLC14A1,TMCC1,ZBTB43,SYN2,TBCEL,TIMP4,TNS1,RUNDC3B,HIRA,PLSCR4,EPM2A" Drug 2119_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.69E-05 1.00E+00 1.29E-03 1.45E-02 41 197 "MTUS1,DOC2A,KCNAB2,APC,GAS7,PDE8B,LHX2,COL9A3,LRIG1,PDE4DIP,CNTNAP2,ARHGEF4,HIPK3,FCF1,EIF4G2,MTSS1L,ETV1,POMT1,CINP,CGREF1,SIGLEC8,GATM,POLL,GUCY1B1,KCNF1,PALM,PDE4A,PDE4D,PFKFB4,SUSD4,ZCWPW1,FNDC3A,BTBD7,TSNAXIP1,ZBTB43,PHLDB1,FBXW11,TIAM1,USP1,ZNF24,TFIP11" Drug 6658_DN Luteolin [491-70-3]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "ADRB2,NME5,LGR5,ZBTB10,BCL7A,CLCN3,HOMER3,GIT2,RHOBTB1,DPH1,FAM13A,TUBD1,ANKMY1,FYN,GAD1,B4GALNT1,GUCY1B1,IFI16,INPP1,KHK,MAPT,NDP,NEK1,NF1,PLCD1,SAMD9,WDR25,RGS4,SH3GL3,SYT1,SATB2,DNAH7,TMEM121,GPR161,TIAM1,NR2C2,XRCC4,SMIM8,ADAMTSL3,TIGD6" Drug 3605_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "NME5,BIN1,EPB41L5,APLP1,PPP4R4,PLA2G4C,KIF1A,CFLAR,SGCE,CA4,PLAA,CLCN3,DAPK3,ACOT8,HIPK3,SUGP2,ENO2,ZNF589,FHL1,GRB10,GSN,IL6ST,ITPKB,JAK2,KCNN2,ADAM22,MINDY2,PRKAR1B,PTN,SLC25A36,PPP4R3A,ZHX3,ARHGAP26,CLSTN2,SS18,RGL1,TBCEL,ZKSCAN5,ZFP37,PHTF2" Drug 4283_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "RALGAPA1,AK2,CDC42BPA,PKP4,APC,SPAG9,CLCN3,RAB26,EXOG,EDIL3,FCF1,MBNL2,OGA,CRCP,FERMT2,AGFG1,IL6ST,MAP4,MMP16,MYO6,NFIX,RETREG1,STRN3,PTN,SLC25A36,KIRREL1,SEC14L1,CCDC88A,ZNF667,KDM4B,SP4,ZBTB43,PRRC2C,TBL1X,ZEB1,DICER1,TMPO,KAT6B,EVI5,KAT6A" Drug 7154_DN Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "ARNTL,MARK4,AKAP7,DZIP3,ARHGAP32,PARD6A,EIF5,RGS17,VPS13B,F8,ZNF589,FGFR1,DIDO1,GSN,KHK,MEIS1,MMP16,TAGLN3,ZSCAN32,RGS4,ZNF671,CSRNP3,BTBD7,KDM4B,ARHGAP26,ZC4H2,STX1A,ARHGEF9,KIAA0930,TRIM2,TNS2,TMEM121,HEY1,KAT6B,NPDC1,TRIM9,NDRG4,HPS4,FZD3,SENP7" Drug 7486_UP CP-319743 [172078-87-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "LTBP4,APBB2,APOC1,ARRB1,N4BP2L1,ATP6V0A1,ADAM15,MTMR3,GYG2,LDLRAD4,CAMK2B,ARHGEF2,LHX2,CRMP1,CRYM,SUSD5,VCAN,TBC1D5,DGKG,FEM1B,SPEG,AGAP2,GLYR1,GPER1,GRB10,MMP17,NF1,NECAB2,PRKCB,SEMA6D,SLC6A8,SLC9A5,BTBD7,SNCA,VPS13A,WSCD1,TRIM2,TRIO,KCNK12,SENP7" Drug 5085_DN Iodipamide [606-17-7]; Down 200; 3.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.13E-05 1.00E+00 1.35E-03 1.52E-02 40 191 "MTUS1,ALDH7A1,ADGRB2,MPDZ,CACNA1A,CBFA2T2,RCHY1,DAPK3,CDON,EGFR,MBNL2,IRAK4,ETV1,VPS26C,ANKMY1,ZNF589,B4GALNT1,TMEM8B,IL6ST,JAK2,KCNN1,LIFR,MT1M,NF1,STRN3,KIRREL1,AP1AR,CSRNP3,ZFP30,SLC14A1,ZNF415,NXT2,TMPO,SSBP2,UGT8,VGF,WNT7A,ZNF74,EVI5,PHTF2" Drug CID000003838 KN-62 Stitch 9.21E-05 1.00E+00 1.36E-03 1.54E-02 46 230 "ADRA1B,SLC4A4,ALDH7A1,CACNA1A,CACNA1B,CALM1,CAMK2B,CCK,KRIT1,LRBA,MYL6B,HDAC9,HDAC4,DBI,MYEF2,EDN1,EDNRA,PTK2B,CAMKK2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,MYLK2,ITGAM,P2RX7,P2RY1,PDCD2,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,PTK2,RYR3,FNDC3A,SNAP25,STAU1,ARC,SYN2,CABIN1,VIPR2,P2RY12,PLD4" Drug CID000448294 AC1L9LT0 Stitch 9.49E-05 1.00E+00 1.38E-03 1.56E-02 29 123 "ANK2,APC,CASK,RIPK1,MPDZ,LARGE1,MAGI1,DLGAP1,PICK1,ARHGEF4,PARD6A,EPB41,APC2,MPP6,SDCBP2,GRIA2,GRIN2C,GRIN2D,KCNJ16,LMO2,NFE2L2,PTPN13,MAPK12,SEC14L1,SLC22A4,FBXW11,NEIL2,UBC,UBE3A" Drug 6965_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 9.57E-05 1.00E+00 1.38E-03 1.56E-02 39 185 "NDRG3,AP2A2,PKP4,ATP2A2,MPDZ,RAB29,CA12,CAMK2G,SCARB1,EPS15L1,COL4A5,GREB1,DAPK3,GIT2,EXOG,DTNA,RASGRP1,EGR3,NOP56,TJAP1,IL6ST,JAK2,IPO5,MEIS1,NCAM2,NFYA,PFKFB3,SMOX,POLG,PRKAR1B,RET,RGS3,SGK1,NUBPL,ZSWIM8,CAMTA2,SIK3,TRIO,VAV1" Drug 2457_UP Hexetidine [141-94-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.57E-05 1.00E+00 1.38E-03 1.56E-02 39 185 "BIN1,DNAH17,CFLAR,USP2,CD86,CD38,CHRNA4,PICK1,CREM,CSF1,SIPA1L1,VCAN,DOCK4,GPRASP1,FCF1,MBNL2,BAIAP2,PRKAG2,FHL1,AFF2,POLL,GNG4,GRM8,IFI16,JAK2,MX1,NOVA2,P2RY1,TREM2,BCAS3,WDR25,KHDRBS2,RGS12,ATP10B,AP4E1,TK2,VGF,SLC17A7,SENP7" Drug 4365_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.57E-05 1.00E+00 1.38E-03 1.56E-02 39 185 "C1QTNF3,APBB2,CAMK2G,SRSF11,FOXN3,LHX2,RAB26,DPYSL2,ING4,ERCC2,ARMCX1,TMEM164,SEMA4D,SYT17,SESN1,STON1,RNFT2,MUM1,ITPKB,MAPKAP1,MBOAT7,RET,RGS12,SBF1,FAM214B,VPS13A,PLCB1,ASTN2,TBL1X,KIAA0930,TNS2,TMEM121,ZMAT3,SLC44A1,BEX4,RUNDC3B,ZNF32,REEP1,MPPE1" Drug 3369_DN Rolitetracycline [751-97-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.57E-05 1.00E+00 1.38E-03 1.56E-02 39 185 "ASPHD1,EPB41L5,ARHGDIG,CFLAR,RCHY1,ENTPD4,GIT2,DBT,RCAN1,MBNL2,ING4,FGFR1,OGA,ZNF44,GLYR1,FERMT2,GPD2,TDRKH,IL6ST,MBD1,MITF,ADAM22,ZNF862,NF1,CNOT4,SLC11A2,PIK3R1,RETREG1,STRN3,SLC25A36,TRA2B,COA1,SNCA,SS18,DMXL2,TRIM2,PCDHA6,TMPO,HIRA" Drug 3638_UP Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,AK2,ALK,CDC14B,ATP2B2,AZGP1,CAMK2B,SCARB1,ARMC8,NCOR2,AATK,CSF1R,KLHL3,CDON,EDN1,F5,REEP2,INPP5B,KCNN1,KIF5A,LIG4,MGAT3,MIA2,MN1,ZNF862,NELL2,NF1,PLTP,MTRF1L,CEP41,RNASE1,RXRA,S100B,ASAP3,NLGN1,PKNOX2,PHLDB1,SYN2,DMXL2,OBSL1,SPHK2" Drug 2264_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,NDRG2,SPARCL1,AMPD3,MARK4,ATP2B2,BACH1,RUNX1T1,CBFA2T2,CLGN,PLEKHB1,WHRN,COL9A3,NECTIN3,PARD6A,EDN1,EDNRB,VPS13B,STX2,CDKL3,SEPT9,GRM2,IL6R,KIF5A,KPNA5,NPY,PLCB2,PNMA3,PMP22,MINDY2,PTCH1,CCDC40,ZFHX4,SCN2B,CCDC88A,WSCD1,ZEB1,R3HDM1,TNS1,FLRT2,XRCC4" Drug 1942_UP Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,ADORA1,AGT,APBB2,PDE8B,CACNA1A,CALB2,KRIT1,CACNA2D2,CNTFR,SH2B1,SUGP2,TNK2,SRPK3,SEC23B,CRCP,DIDO1,SPACA9,CACFD1,NCKAP1L,SYNPO,TJAP1,GIT1,MYT1,NTRK2,DUSP26,PPARA,PPP5C,APTX,PTH1R,RNASE1,RXRA,LIMS2,SNAP25,ZC3H13,PHLDB1,SYN2,ZKSCAN5,VGF,VIPR2,ZNF24" Drug 2162_DN Gelsemine [509-15-9]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "PKP4,PPP4R4,MARK4,SYNJ2,SCAPER,C5,USP2,FOXN3,RAB33A,CNTN1,CREM,ARHGEF10,ZNF337,TM9SF4,ING4,TNK2,RASGRP2,ZNF589,AFF2,SRCAP,USP19,CACFD1,MX1,MYT1,CNOT4,MBOAT7,POU6F1,MINDY2,MAPK3,ZSCAN32,RGS3,DCUN1D2,PREX2,ZKSCAN3,KDM4B,DOK5,PLCB1,TPM1,ZKSCAN5,ZNF225,PHTF2" Drug 7484_DN Ajmaline [4360-12-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG3,ADCY6,OSBPL1A,AK2,AMT,APLP1,MARCH3,SCAPER,TAOK2,AKAP7,GREB1,DCAF8,HDAC4,ZNF337,JAKMIP2,HIPK3,EIF5,SCML2,PRKAG2,GALC,ALDH1L1,MALT1,CNTRL,IDH3B,KHK,LIG4,GIT1,PPP3CC,ACSS3,FAM184A,ZCWPW1,GTDC1,RGS12,SH3BP2,FERMT1,LIMS2,BTBD7,TBL1X,PLPPR2,VIPR2,KCNAB1" Drug 264_UP MK-886; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "KDM5D,BRAP,ARNTL,GYG2,CACNA1I,CA8,KALRN,CAMK2A,PDE4DIP,DCAF8,INTS1,TNK2,ERCC2,FOLR2,SEPT9,NEU3,TXNL4A,GRM2,PTPRT,SOX21,IRF8,ITPKB,KCNJ5,L1CAM,MGAT3,MX1,NNAT,GPR173,PNMA3,POLG,WDR25,SH3TC2,RGS4,FNDC3A,ABLIM3,FAM214B,SLC12A4,IFT122,PHLDB1,MPPE1,JPH3" Drug 2356_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APC,CDK10,BCL7A,CFLAR,SCAPER,CAST,LRRFIP1,CLCN3,IQCK,BAG4,CLOCK,OSBPL3,CYBB,SGSM2,ANKMY1,ZNF589,FGFR1,CRCP,LILRB4,CACFD1,ITGAM,MIA2,NFYA,SLC11A2,PIK3R1,RETREG1,MAPKAP1,TMEM104,C1orf54,CCDC25,CLIP1,PEX26,SEPT8,KANK1,EXOC7,TBL1X,TLR4,PARD3,KAT6B,NR2C2,XRCC4" Drug 3711_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,ADCY6,PKP4,APC,GAS7,SLC4A4,ATP2A2,C5,IL33,RAB28,PICK1,ARHGAP24,MAML1,DAPK3,PLPPR4,TMCC2,ACOT8,OPTN,TUBD1,SCML2,FGFR1,CINP,GLYR1,MT1M,CCSER2,MAPK7,SAMD9,ZDHHC14,KCTD17,OGDHL,ARHGAP26,SPTB,SYNE1,TMPO,TNS1,TPM2,TRIO,REEP1,UPF3A,GDPD5,VPS35L" Drug 3975_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SYN3,BEGAIN,TRMT9B,BIN1,APBA2,APLP1,APOC1,CDK13,RGS9,KSR1,CACNA1I,CAMK2B,CDH2,WHRN,EGR3,ZNF391,ANKMY1,REEP2,CORO2B,FGFR1,FHL1,ALDH1L1,LYVE1,HPGDS,GRM8,AP4S1,TJAP1,KCNN1,L1CAM,ADAM22,MYT1,PALM,SAMD9,C1orf54,RFX3,SMPD3,MRAS,CDK19,WSCD1,LAT2,TIGD6" Drug 4681_DN "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NME5,ATP1A3,SLC4A4,STX16,FUBP1,LDLRAD4,CLTB,ABCG2,CREM,SH2B1,AATK,MFAP3L,CHRDL1,EDNRA,FEM1B,TENM1,COQ7,ZNF549,CDKL3,ANKMY1,CORO2B,FYB1,ICA1,MMP16,NDP,NF1,NNAT,STRN3,CNNM2,FAM184A,FRMPD1,SIRT2,ZKSCAN3,SNCA,DOP1A,SOX15,IZUMO4,ASTN2,THRA,OSBP2,VIPR2" Drug 4562_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AP2A2,SEMA6A,APBA2,ADAM23,CFLAR,ST3GAL5,IL33,CAMK2B,SCARB1,ARHGAP33,SOCS6,TPP1,HOMER3,CPS1,AATK,ING4,DENND4A,ZNF589,ANKFY1,NSG1,FYB1,GAD1,MAP2,MBD1,NLE1,PLCD1,GRAMD1C,PRPH,GDPD2,PTPRN2,RGS12,SH3BP2,ASAP3,FNDC3A,TMCC1,ZHX3,HECW1,ARHGEF9,THRA,TPM1,TPM2" Drug 7551_DN vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "PPFIA3,CA12,CAMK2B,KYAT1,QKI,HOMER3,CRY2,NCOR2,ABCG1,PDE4DIP,DAPK3,DTNA,ATP2C1,MPP6,OGA,KCNMB4,GNG4,NXPH3,KHK,LSS,MATK,MMP16,MSI1,NACA,LRP12,RIPOR1,RGS12,TCP11L1,RPS6KA2,SEC14L1,FBXO11,CCDC88A,RCOR3,SNCA,SP4,PBLD,ANKRD12,TRIM2,TNS2,RPRM,ZNF45" Drug 3848_DN Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "CDC42BPA,APC,PLA2G4C,CDK13,DNAH17,MARK4,SLC4A4,AKAP7,RIMS2,DCAF4,CELSR3,MBNL2,ELN,CGREF1,SRCAP,GFER,GRIK5,ICA1,MIA2,MYO7A,ZNF862,NF1,PCDH9,PDPK1,PLCD1,PPP5C,RELN,SNRK,ZDHHC14,ASAP3,SMARCD3,SYN2,KIAA1107,ZNF34,THRA,FAM155A,PLPPR2,VIPR2,LAT2,REEP1,KCNAB1" Drug 2155_UP Vitexin [3681-93-4]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,MTUS1,ALK,BIN1,CDC42BPA,LGR5,CASK,CFAP410,THSD7A,CHN2,STOML1,CREM,PPP1R16B,USP6NL,HEPH,RUSC2,SGSM2,EDIL3,ERBB2,HPCAL4,ALDH1L1,GRM2,TJAP1,MAP4,MYO9A,ZNF862,NNAT,PDE4A,PFKFB4,PTPRN2,RIPOR1,MARCH1,FAT4,RFX2,MAP6D1,ST6GAL1,EXOC7,CRTC1,CLIP2,SPHK2,EVI5" Drug 2467_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SRPX,AMH,BIN1,OGT,PRX,CDO1,CHRNA4,ABCG1,CRYM,ZFYVE16,SEZ6L2,FAM13A,PLXNC1,RASGRP2,MTSS1L,FGFR1,AGAP2,GPR75,KCNJ5,KIT,MAPT,MMP16,NRCAM,PCSK5,PDE4D,PGAM2,WDR25,PTPN13,MARCH1,SALL1,EPN2,PKNOX2,SPTB,PLCB1,SYT5,TACR1,MTCL1,TPM1,UBE3A,ZBTB38,KCNAB1" Drug 4598_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADD2,C1QTNF3,ARRB1,ST3GAL5,FUBP1,MYRF,SLC16A4,ARHGEF2,CHN2,SULT4A1,NRG2,CREM,ABCG1,SUSD5,PHF14,ARHGEF4,RIMS2,SEMA3D,PLXNC1,ERBB4,NCALD,C2orf72,IGF1,IL12A,MMP16,NPR2,PCDH9,BCAS3,CCDC40,C1orf54,RGS3,FBXW7,ATXN7,NLGN1,DHX30,SMARCA4,TSNAXIP1,IZUMO4,CDK19,PCDHA5,GAN" Drug 7064_UP 0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMT,GAS7,SLC4A4,SLC2A11,CALB2,CBFA2T2,CRLF1,QKI,CRY2,BRINP1,HSD17B14,ANKMY1,AHDC1,GLYR1,FERMT2,GPER1,GRB10,SLC2A6,KCNH2,MAP2,MPP2,LYRM9,NEK1,NPR2,CDK18,PLCD1,PRPH,TRIM68,RNASEL,RPS6KA2,KDM4B,PHLDB1,ARHGEF9,CHST8,SLC44A1,HEY1,KAT6B,LMF1,REEP1,MAP3K12,SLC17A7" Drug 2274_DN Methocarbamol [532-03-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,ADRA1D,CDC42BPA,APLP1,FAM131A,ARRB1,SLC4A4,ALDH7A1,CFLAR,KRIT1,TAOK2,HOMER3,CNTN1,ABI3BP,RASSF2,MAML1,DBN1,DTNA,NCALD,ZNF589,FGF12,IQCG,PRELID3A,SRCAP,MSL3,STON1,SPACA9,INPP5B,ITPKB,JAK2,MSI1,ZNF862,PLCD1,PPP2R2B,GRAMD1C,ELOVL2,RGS3,TSNAXIP1,GDPD5,KAT6A,PHTF2" Drug 7310_DN Chenodiol [474-25-9]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "MTUS1,CDC42BPA,APOC1,PPFIA3,MARCH3,MARK4,CFLAR,ST3GAL5,ARHGEF2,CPS1,KLHL3,SGSM2,TENM1,MRNIP,SPEG,B4GALNT1,AHDC1,SLC2A6,FAM69A,L1CAM,NF1,NPR2,SLC11A2,SAMD9,PTPRN2,SH3TC2,RPS6KA2,RXRA,SBF1,KBTBD4,SMARCD3,TTC17,CDK19,ELOVL4,PHLDB1,JMJD6,IQCE,SZT2,ZNF34,R3HDM1,MPPE1" Drug 4447_DN nordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,C1QTNF1,C1QTNF3,PPFIA3,PPP4R4,MARK4,SLC4A4,ADGRB2,CBFA2T2,ARHGAP33,TAOK2,CREM,OPTN,ING4,SPEG,FGFR1,SCARA3,POMT1,DENND2A,INPP5K,TDRKH,IL12A,INPP5B,MAPT,KITLG,MX1,MINDY2,BCAS3,PID1,ZNF821,ASAP3,SIRT2,MYH15,TMCC1,COBL,ZEB1,TMPO,UBE3A,XRCC4,EPM2A,PHTF2" Drug 3003_DN Reserpine [50-55-5]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,N4BP2L1,SYNJ2,SLC16A4,ENTPD6,FOXN3,RCHY1,PDE4DIP,SLITRK5,RUBCN,KIAA0586,DAPK3,TOM1,HIPK3,MBNL2,PLXNC1,MTSS1L,ZNF589,FGFR1,EFCAB2,SEPT9,ITGAM,MGAT3,STRN3,MINDY2,ZSCAN32,PTPRO,GALNT10,NLGN1,BTBD7,ZHX3,CDK19,TROVE2,SYT5,TCF4,SLC44A1,TPM1,SMUG1,LMF1,LAT2,PHTF2" Drug 6603_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADD1,C1QTNF1,ADGRF5,ALK,SEMA7A,DDO,CDC14B,RASL11B,ATP6V0A1,CACNA1I,TAOK2,RGS6,VCAN,DTNA,EDIL3,EDNRA,EDNRB,FGF1,TRAF3IP2,GNAO1,GPD1,PRUNE2,KCNB1,LAMA2,MATK,KITLG,NF1,PFKFB4,PPP1R1A,PRKAR1B,C1orf54,RGS12,KLHL11,KCNIP1,ASAP3,SLC2A5,SAMSN1,COBL,THRA,TIMP4,LAT2" Drug 4228_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,ADORA1,AP2A2,PKP4,APAF1,KCNAB2,PPP4R4,NCOA1,SLC2A11,BMP7,BAIAP3,KRIT1,FOXN3,ASIC3,CNTFR,CRY2,CSF1,MAML1,MFAP3L,SPOCK3,DTNA,ETV1,FGF1,DCTN2,NSG1,STON1,GSTM5,IFI16,MARK1,NTRK3,PCDH9,PDE4D,SERPINI1,C1orf54,GAL3ST4,PKNOX2,LIMCH1,ZFPM2,GPR161,ZNF225,KCNAB1" Drug 6378_DN valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADCY6,APBB2,PPP4R4,SLC2A11,GYG2,MYRF,THSD7A,CBFA2T2,ARMC8,ERC2,DCAF4,GPRASP1,RUSC2,C2CD2L,DTNA,FRY,MBNL2,PLXNC1,MTSS1L,FGF1,ERAP1,CPLX2,RUNDC3A,MGAT3,NTRK2,GPR85,CNTLN,ZSCAN2,C1orf54,ZNF671,FBXO11,SLC11A1,ASTN2,TCF4,TK2,RPRM,FLRT2,SPHK2,REEP1,PHTF2,DPF3" Drug 4371_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AP2A2,AMPD3,AMT,APLP1,DNAH17,BMP7,SYNJ1,GYG2,CA12,CRLF1,SOCS6,ASIC3,PLAA,CNTFR,CNTNAP2,EGR3,PLXNC1,TNK2,VPS13B,STX2,OLFM1,FGFR1,FGFR3,SEMA4D,PRELID3A,GPR37,TJAP1,KIFC3,KIT,MID1,NF1,MAPK10,PTPRE,RAD51D,FAM184A,ZCWPW1,PLCB1,MCF2L,TK2,CDK20,FAM155A" Drug 3107_DN Adrenosterone [382-45-6]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "MTUS1,APOC1,PDE8B,CAMK2G,ARHGEF1,ENTPD6,AKAP7,CREM,SIPA1L1,DGKG,KIAA0753,RUSC2,C2CD2L,TNK2,CDKL3,PTK2B,DLC1,TPK1,CGREF1,CSPG5,ICA1,LAMA2,MAP4,MEF2C,AFDN,GIT1,ZNF862,OXTR,SLC25A23,ZSCAN32,ZCWPW1,ZDHHC14,FAM214B,ZHX3,PDLIM2,PARD3,TPM1,ZKSCAN5,MKRN3,GDPD5,TIGD6" Drug 4956_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,NDRG2,ADORA1,C1QTNF1,FAM131A,MARK4,ALDH7A1,CFAP410,KALRN,RUNX1T1,CLTB,CNTFR,CRY2,CSF1,DAPK3,GSDME,EDNRB,FOXF2,ZNF44,GAD1,GNAO1,PCLO,MX1,MYT1,NOVA2,ELOVL2,KLHL11,TCP11L1,SLC2A5,PKNOX2,SLC9A5,SNCA,ARHGAP26,RGL1,WSCD1,CRTC1,CABIN1,TNS1,VIPR2,KCNAB1,JPH3" Drug 3620_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,ALCAM,AMT,GYG2,BAIAP3,LDLRAD4,CACNA1A,NECTIN3,PDE4DIP,PPP6R2,EDNRA,PLXNC1,STX2,FGF12,FGFR1,FOXF2,OGA,GCNT2,SRCAP,GPER1,SPACA9,ATXN2L,ADAM22,NPTX2,MINDY2,PPP5C,PRKCB,RELN,TMEM104,PTN,ZSCAN2,ZNF821,SLC2A5,DOK5,SPTB,KIAA1107,PCDHA5,DNAH7,TNS1,PIK3R5,ZKSCAN5" Drug 2286_DN Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "LTBP4,DOC2A,PPP4R4,ARRB1,CLGN,B4GALT6,BAG4,DTNA,DUSP9,ZNF589,SRCAP,GLYR1,POLL,SPACA9,ITPKB,KHK,LSS,MAP4,KITLG,ADAM22,ZNF862,NPR2,OGG1,CDK18,PLEC,KCTD17,KLHDC8A,TCP11L1,SBF1,SH3BP2,PPP4R3A,KIF13A,TROVE2,ARC,NSD1,PCDHA6,TRIO,ZNF24,DNALI1,EPM2A,JPH3" Drug 5832_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADGRF5,ALK,BIN1,APBB2,SEMA4G,PPP4R4,CFLAR,ST3GAL5,HAP1,B4GALT6,PHF14,GIT2,IRAK4,NRN1,FGFR1,BAIAP2,SRCAP,GNAO1,PRUNE2,TDRKH,TJAP1,KCNF1,MX1,NEFM,NPTX1,PIK3R1,MAPK10,AMBRA1,SLC9A5,TMCC1,KDM4C,TROVE2,NXT2,CEP68,ASTN2,TRIM2,DOCK9,TPM2,WIPF1,PHTF2,RNF146" Drug 2460_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG3,BEGAIN,APBB2,RASL11B,KIF1A,BMP7,FUBP1,USP2,HOMER3,CSF1,PHF14,TBC1D5,E2F5,MRNIP,EIF1,PTK2B,KAT8,ANKFY1,TRAF3IP2,INPP5K,HSF2,IL6R,KCNJ5,NF1,OPRL1,CCSER2,ZNF426,PPARA,FAM184A,ZFHX4,CXXC4,ZNF667,ATP10B,SS18,NXT2,KANK1,DNMBP,AP4E1,TPM1,SSBP2,ZNF24" Drug 4661_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,AMPH,KCNAB2,APC,ST3GAL5,GYG2,CACNA1I,CFAP410,TPP1,STOML1,RAB26,HOMER3,AKAP5,PDE4DIP,C2CD2L,DPH1,TOM1,EGFR,EZH1,ABCA8,ZNF589,GATM,LYVE1,GPD1,STMN2,ATXN2L,HLF,ADAM22,LYRM9,CNOT4,P2RX7,RETREG1,RAD51D,ENOX1,KCTD17,DOK5,EXOC7,SMG6,CDK20,TRO,JPH3" Drug 2640_DN Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,PPFIA3,ARHGDIG,RIPK1,ST3GAL5,ARHGEF7,CFAP410,CAMK2B,FAM189A2,SLC4A8,BAG4,CREM,NCOR1,ARHGEF4,DAPK3,FBXL5,EPB41L2,F8,FAM49B,GPER1,RNFT2,MAN1B1,HNMT,LIG4,NF1,RIPOR1,CEP97,ROBO1,SGK1,EPN2,ELMO2,ZBTB43,TSPYL2,CLASP2,STX1A,EXOC7,VAV1,CLDND1,REEP1,EMSY,ACTR3B" Drug 7317_UP Quinic acid [86-68-0]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "KCNAB2,APC,ALDH7A1,ADGRB2,NRP2,CFLAR,SYNJ2,BAIAP3,CHRNA4,AKAP5,HAPLN1,MFAP3L,RUSC2,DRP2,POMT1,PDLIM5,GAD1,GRM8,HNMT,IFI16,KCNF1,MMP16,LYRM9,NDP,PDE4D,AMBRA1,SNCA,SPTAN1,DDN,TROVE2,ELOVL4,TCF4,SYNE1,TIAM1,TK2,CABIN1,TPM2,OSBP2,WIPF1,XRCC4,MPPE1" Drug 4609_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,BIN1,CASK,NCOA1,ADGRB2,SYNJ2,CFAP410,ARHGEF1,B4GALT6,ABCG2,QKI,HOMER3,PPP6R2,RUSC2,MBNL2,RRAGB,FER,ANKFY1,DHX35,FAM69A,INPP5B,MX1,NDP,NFYA,PLCD1,LRP12,WDR25,TMEM231,SH3TC2,GTDC1,CLIP1,ZFP30,COA1,NXT2,EXOC7,TCF4,ZNF34,BEX4,CABIN1,MAP3K12,EMSY" Drug 4066_DN Xylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,MTUS1,AMPD3,CDC14B,MARK4,ATP6V0A1,NRP2,BAIAP3,LDLRAD4,LHX2,PDE4DIP,MFAP3L,PLXNC1,CORO2B,DLC1,ST3GAL6,FGFR1,EFCAB2,GNAL,IL6ST,INPP5B,KIFC3,MAPT,ADAM22,ZNF862,NNAT,NOVA2,RETREG1,NLE1,CNNM2,ZMAT4,CCDC102B,TCP11L1,MAP6D1,MRAS,MCF2L,KIAA0930,SYNE1,CRTC1,TRIO,HIRA" Drug 3091_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APC,MARK4,SLC4A4,KIF1A,BMP7,CACNB4,SCARB1,CDO1,SLITRK5,DZIP3,DGKG,HIPK3,OPTN,ELN,ZNF549,AFF2,CSPG5,FYB1,GATM,POLL,GPD2,IL6ST,KCNN1,LAMA2,MPP2,MX1,NF1,NNAT,SERPINI1,PLCD1,PLCL1,BEND5,SLC2A5,SLC6A8,SNCA,KDM4B,PHLDB1,PLCB1,PLPPR2,LAT2,ZNF74" Drug 3929_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADORA1,C1QTNF1,DOC2A,APAF1,MTMR3,CLGN,LY86,CRY2,VCAN,DCAF4,CYBB,TNK2,ELN,MTSS1L,ERCC2,FGFR1,FHL1,DCTN2,FOLR2,NSG1,SRCAP,LYVE1,MBP,MID1,MSI1,PCBP3,NTRK2,OGG1,PDE4A,C1orf54,RFX2,STUM,SH3BP2,CNKSR2,PKNOX2,FAIM2,PDZD2,UNC5B,SSTR2,SLC30A3,DPF3" Drug 5393_DN Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,APLP1,GYG2,CFAP410,HAP1,TAOK2,LHX2,SH2B1,PDE4DIP,MAML1,MBNL2,ZNF589,EFCAB2,FAM49B,SEPT9,INPP5K,GCNT2,GNG4,SPACA9,ATXN2L,ICA1,INPP5B,KCNH2,LSS,MGAT3,MIA2,ADAM22,NPTX1,CCSER2,NLE1,PLEC,PLXNB1,PRKAR1B,TMEM104,ELOVL2,RGS12,SH3BP2,SMARCA4,SPTAN1,TRIM2,GDPD5" Drug 4669_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "TRMT9B,AMT,PPFIA4,CDC14B,EIF4G3,ADAM23,ABCG2,AKAP7,ARHGEF10,PDE4DIP,CNTNAP2,BRINP1,CNNM1,OPTN,ING4,CDKL3,ETV1,MSL3,GRM8,ITPKA,AFF1,NEK1,NF1,STRN3,TMEM231,KIRREL1,ZNF671,RPS6KA2,ZNF821,FRMPD1,SMARCD3,SNCA,KDM4C,ARHGAP26,IQSEC2,SUPT5H,PLCB1,TBL1X,TNS1,WNT7A,NT5M" Drug 5723_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADD2,ADRA1D,AP2A2,APC,PPFIA3,SLC4A4,ADGRB2,BMP7,SCAPER,GYG2,CAMK2B,DCLK1,PLEKHB1,CNTN1,CRMP1,RIPOR2,PLXNC1,IRAK4,IGSF6,ZNF391,CDKL3,KCNN1,KIT,MMP16,NF1,PALM,PIK3R1,MTRF1L,PILRA,PTPRB,TCP11L1,SLC8A1,HECW1,SPTAN1,JMJD6,TBCEL,SZT2,PIK3R5,RPRM,SLC17A7,KCNAB1" Drug 1712_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; HL60; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "CDK10,SEMA4G,PDE8B,SLC4A4,ADGRB2,CA12,CACNA1A,CALB2,CACNA2D2,FOXN3,CHN2,CNTFR,SH2B1,TMCC2,TNK2,SRPK3,ELN,ALDH1L1,CACFD1,GSTM5,KCNF1,KIF5A,MBP,GIT1,SAMD14,MYT1,DUSP26,PPARA,PPP5C,PTK2,PTN,PTPRN,RXRA,SEMA6D,LIMS2,ZC3H13,PHLDB1,SYN2,DNAH7,VGF,VSNL1" Drug 6501_DN Aminocaproic acid [60-32-2]; Down 200; 30.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AP2A2,AMT,APLP1,CDC14B,NCOA1,MAGI1,CREM,ABCG1,CSNK1E,DZIP3,DAPK3,GIT2,EDNRA,ING4,ENO2,DENND4A,MALT1,GNG4,GPR37,GRIK5,INPP5B,KCNH2,MAPT,MIA2,OCRL,CNNM2,TCP11L1,SAFB,SBF1,ZNF821,EPN2,FAM214B,RBM34,KDM4C,NXT2,TTBK2,NSFL1C,EXOC7,TNS2,TPM1,XRCC4" Drug 5405_DN Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,APC,APLP1,ALDH7A1,SLIT2,SH2B1,PPP6R2,GIT2,ZNF804A,MFAP3L,ACSL4,SYT17,AHDC1,RUNDC3A,MSL3,TDRKH,ATXN2L,ELOVL5,MAP4,MPP2,NF1,PCDH9,PLXNB1,MINDY2,MAPK7,RGS12,NEK11,RPS6KA2,SBF1,EPN2,LIMCH1,UNC5B,ST5,MCF2L,CRTC1,SLC44A1,TK2,RUNDC3B,VLDLR,EVI5,GDPD5" Drug 2969_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BIN1,MARK4,SYNJ2,CD86,CLGN,ARMC8,CPS1,SH2B1,CRY2,SIPA1L1,EIF4G2,MRNIP,EIF1,FER,FGFR1,PCYOX1,GALC,INPP5K,PCLO,SCAMP5,MX1,NPR2,NRCAM,PDE4A,ENPP2,ZCWPW1,MAP6D1,AMBRA1,ANKRD6,FAM214B,TMCC1,KDM4B,TSPYL2,SEPT8,DNMBP,AP4E1,ZKSCAN5,PLPPR2,LAT2,XRCC4,TFIP11" Drug 3289_UP Biotin [58-85-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,NDRG2,FZD9,KIAA1324,SEMA7A,KCNAB2,PRX,PPP4R4,FOXN3,WHRN,ABI3BP,ARHGEF10,RIPOR2,MFAP3L,DMD,CDON,OGA,POLL,ADAMTS13,KCNN1,KIT,LRP1B,MEF2C,MMP16,ADAM22,NNAT,PTPRH,FRMPD1,ASAP3,FNDC3A,SLC9A5,TSNAXIP1,PCDHGA10,PCDHA5,TNS1,CHST5,TRO,SPHK2,NT5M,KCNAB1,ADAMTSL3" Drug 2175_UP Dipyrone [5907-38-0]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADD2,BIN1,LGR5,LARGE1,LHX2,CREM,CNTNAP2,SHANK1,EGFR,ELN,FGF12,OGA,TMEM8B,INPP5K,GATM,ALDH1L1,ATXN2L,TJAP1,MGAT3,MSI1,ADAM22,MYCN,MYO6,PCDH9,PFKFB4,PTPRN2,RASGRF1,ZFHX4,KLHDC8A,CPEB3,SLC12A4,RBM34,UNC5B,HIF3A,GPR161,CHST5,TRIO,UGT8,LMF1,ZBTB38,GAN" Drug 6055_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMPD3,BIN1,AMT,APLP1,APOC1,MARK4,RHBDL1,ASIC3,SULT4A1,ARHGEF6,WHRN,CNTNAP2,INTS1,DGKG,BRINP1,GSDME,NCALD,CORO2B,FUT9,GCNT2,ADAM28,PCDH17,GRIN2C,KCNJ5,ADAM22,SLC11A2,MTRF1L,MAPK7,TRIM68,CARF,SMPD3,IZUMO4,SPART,TROVE2,JMJD6,DNAH7,TIMP4,TPM1,UCHL1,LAT2,ITM2C" Drug 2541_DN Propidium iodide [25535-16-4]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "TRMT9B,BIN1,MTMR3,CACNA1A,CAPN3,TAOK2,PLAA,CSF1,PDE4DIP,DAPK3,RUSC2,CDON,FEM1B,RASGRP2,CDKL3,ST3GAL6,FHL1,CAMKK2,ZNF44,LILRA2,MAP4,MID1,AFF1,NF1,PLCD1,LRRN3,DEF8,KHDRBS2,EPN2,SLC11A1,MYH15,SYN2,TNS2,THRA,CDK20,TRIO,XRCC4,ZNF32,GDPD5,FAM13C,UBE3B" Drug 5852_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,SPARCL1,ALK,ARRB2,RUNX1T1,KYAT1,CLTB,QKI,CSF1,VCAN,PDE4DIP,CNTNAP2,PPP6R2,MFAP3L,RUSC2,TNK2,EPHB1,FGFR1,NSG1,GRIK5,LIFR,MIA2,NELL2,NTRK3,GPR85,PLCD1,MAPK7,SAMD9,NEK11,ASAP3,ZNF334,KDM4C,CEP68,MCF2L,ADGRL3,KIAA1107,SLC44A1,RIMBP2,ZKSCAN5,WIPF1,KCNAB1" Drug 2575_DN Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BIN1,APC,CDC14B,ADAM15,BCL7A,MTMR3,C5,LDLRAD4,CAST,FAM149A,ENTPD4,CDON,SEZ6L2,RASGRP2,MTSS1L,DLC1,ST3GAL6,PRKAG2,ERAP1,SRCAP,ATXN2L,ELOVL5,KHK,MEF2C,OGG1,PDE4D,CCSER2,MAPK7,PTPRO,RIPOR1,FAM184A,CNKSR2,EPN2,SIRT2,CEP68,IQCE,FBXW11,TNS2,CRTC1,SLC44A1,LMF1" Drug 6323_UP Cefoperazone dihydrate; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,PPFIA3,CDK13,NRP2,SYNJ2,CACNA2D1,CRMP1,ABCG1,CSNK1E,CNNM1,PLXNC1,IRAK4,COQ7,RRAGB,KAT8,ZNF589,BAIAP2,HPCAL4,PRELID3A,DENND2A,GATM,HNMT,PFKFB2,CCSER2,STRN3,CNNM2,PTPRD,SCN8A,SH3BP2,PEX26,CCDC88A,BTBD7,SNCA,LHPP,TROVE2,SS18,TACR1,TK2,TNS1,NT5M,UBE3B" Drug 1299_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,AMPD2,ANK2,PPFIA4,NCOA1,ATP6V0A1,BCL7A,SCAPER,ARHGEF1,SEC31B,INTS1,DBN1,DTNA,PHF20L1,SUGP2,TNK2,MRNIP,EZH1,NOP56,LILRA2,SLC2A6,VSIG4,AGBL5,IRF8,ITGAM,MAP4,MATK,PLCB2,RNASEL,MCMBP,RPS6KA2,SH3BP2,COA1,SMARCC2,SPTAN1,DIP2A,PDLIM2,NSD1,R3HDM1,WBP2,LAMP5" Drug 6025_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AGT,LTBP4,BIN1,PLA2G4C,PDE8B,N4BP2L1,AZGP1,ADGRB2,CACNA1I,CACNA1G,CFAP410,CAPN3,HIP1R,CBARP,EPS15L1,CPS1,CNTNAP2,RUSC2,SHANK1,HSD17B14,ERCC2,PIPOX,REEP2,EFCAB2,NSG1,ERAP1,LILRB4,GPER1,STMN2,HLF,AFDN,NTRK2,LRRN3,PTPRB,KHDRBS2,ZFP2,SLC11A1,TACR1,PRDM10,HRASLS,NLRP3" Drug 4472_UP Estropipate [7280-37-7]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADRA1D,AP2A2,AK2,AMPD3,APAF1,STX16,BMP7,HOMER3,RCHY1,NCOR2,CSF1,DUSP9,ETV1,FGF12,ANKFY1,OGA,RUNDC3A,ZNF276,MAN1B1,ITGA7,JAK2,SMAD1,KITLG,ADAM22,NPR2,POU6F1,MINDY2,ELOVL2,PTPRH,PTPRN2,KCTD17,FBXW7,KIF13A,KDM4B,DOK5,ARHGAP26,IQSEC2,COBL,TRIM2,TNS1,ZKSCAN5" Drug 7524_UP Suramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "CDC42BPA,PPFIA3,SEMA4G,ATP1A3,RGS11,CACNA1I,BAIAP3,CFAP410,CAMK2G,ARHGAP33,TPP1,KIAA0586,GIT2,SPOCK3,DYNC1I1,ERCC2,ZNF589,FLNC,TPK1,SEPT9,PCLO,GRB10,ADAMTS13,DHX35,ADAM11,MMP17,NF1,PFKFB2,SCN8A,ASAP3,PEX26,BTBD7,ZC3H13,ARHGAP26,SZT2,PCDHGA10,SYNE1,TNS1,ZKSCAN5,CLIP2,SPHK2" Drug 2847_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,AMPD3,FAM131A,APOC1,SYNJ2,GYG2,CAMK2G,SCARB1,RCHY1,BAG4,CREM,PDE4DIP,FAM169A,LYPD1,TOM1,CELSR3,IRAK4,ING4,FAM198B,ACSL4,SRCAP,POLL,GIT1,SETD4,ZSCAN2,ZDHHC14,RGS3,ANKRD6,SLC6A8,BTBD7,UHRF1BP1L,SPTAN1,SUPT5H,ARC,EXOC7,SLC44A1,PARD3,CABIN1,LMF1,REEP1,SEMA3B" Drug 4658_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ACHE,AMPH,APOC1,ARHGDIG,DNAH17,ALDH7A1,SYNJ2,CACNB4,USP2,MTMR7,ABCG1,SUSD5,RIMS2,ELN,ERBB4,ETV1,ABCA8,NSG1,GABRA3,GPR75,POLL,BACH2,IRF8,MGAT3,NF1,P2RX7,ZSCAN32,RGS12,TCP11L1,SCN2B,MRAS,CNKSR2,DZIP1,KANSL3,SPTB,ATP10B,RPGRIP1L,PCDHA5,ZNF34,UBE3A,KAT6A" Drug 3398_DN Felbinac [5728-52-9]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APLP1,FAM131A,SCAPER,SLC16A4,CLGN,LY86,ARHGEF6,PICK1,AKAP7,PDE4DIP,GPRASP1,SPOCK2,MFAP3L,EDNRA,FAM198B,AGAP2,IQCG,PDLIM5,PRELID3A,ALDH1L1,SRCAP,RUNDC3A,KIT,NF1,PLTP,STRN3,MAPK10,RASA3,PEX26,SNCA,KIF13A,ZNF423,ELOVL4,RGL1,STX1A,TBCEL,PIK3R5,TRIO,WIPF1,ZFP37,ITM2C" Drug 3367_UP Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADORA1,C1QTNF1,BEGAIN,APAF1,N4BP2L1,CACNA1I,CAMK2B,USP2,AKAP6,CPS1,TMCC2,MBNL2,TNK2,RASGRP2,MTSS1L,PTK2B,GAD1,SIGLEC8,GRM8,ICA1,KCNB1,KIF5A,MEF2C,ADAM22,TAGLN3,ZNF862,NPR2,PDE4D,LRRN3,PPP5C,SAMD9,RNASE1,SH3BP2,ZC3H13,ATP10B,WSCD1,PCDHGA10,PARD3,FLRT2,WIPF1,GDPD5" Drug 6965_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "TRMT9B,BCAS1,ARRB1,GYG2,LDLRAD4,COL9A3,PDE4DIP,ZNF804A,DMPK,DTNA,ENO2,MTSS1L,ST3GAL6,FHL1,FYB1,GCNT2,STON1,LPAR4,GPR37,SPACA9,HLF,MAP4,MAPT,MBD1,AFDN,PCDH9,PRPH,PTX3,PREX2,PKNOX2,BTBD7,STX1A,IQCE,TRIM2,TK2,TPM1,RUNDC3B,LMF1,KCNK12,TFIP11,GDPD5" Drug 6594_DN 5194442; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NME5,APBB2,EIF4G3,QKI,RAB26,SLITRK5,FAM131B,DYNC1I1,ST3GAL6,CINP,MSL3,GPD2,AGFG1,DHX35,IFI16,SHISAL1,INPP5B,MAPT,NACA,PLEC,SLC25A23,PPP5C,GRAMD1C,BCAS3,WDR25,PTPRN2,PTX3,GAL3ST4,NEK11,RPS6KA2,AMBRA1,LIMS2,KDM4D,BTBD7,PHLDB1,TCF4,OBSL1,BEX4,TNS1,CHST5,XRCC4" Drug 5837_UP Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADGRF5,AMT,APOC1,PPP4R4,SLC4A4,ALDH7A1,RAB29,CFAP410,HAP1,LARGE1,CNOT8,USP6NL,DCAF8,GIT2,CDON,ABCA8,FGFR1,SEMA4D,EFCAB2,PDLIM5,DISC1,GLI2,ADAMTS13,LAMA2,LIG4,MAN2A2,NF1,PIK3R1,MAPK3,BCAS3,PTN,SUGCT,NEK11,WDR37,KDM4D,SMARCA4,SPTAN1,SS18,PCDHA5,AP4E1,DPF3" Drug 2274_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "GAS7,CALB1,CBFA2T2,CDH2,ASIC3,CHRNA4,CPS1,NCOR2,CSF1R,SPOCK2,HEYL,ERCC2,ANKMY1,REEP2,NEU3,GNAO1,GRIN2C,GRM8,HLF,VSIG4,IGF1,KCNJ5,MN1,MX1,NF1,NTRK2,WDR25,PTCH1,C1orf54,NUDT11,RORB,ASAP3,SLC2A5,SPP1,PHLDB1,SYT5,ZEB1,GPR161,TLR4,LAT2,SLC17A7" Drug 6200_UP "estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BIN1,CDC14B,CDK10,SLC4A4,ATP6V0A1,CFLAR,BMP7,CBFA2T2,NCOR2,CSF1,ARHGEF10,PDE4DIP,DAPK1,DAPK3,SEZ6L2,TNK2,MRNIP,C3orf18,VPS13B,ANKMY1,BAIAP2,AGAP2,SEPT9,KCNJ5,KHK,MYO7A,CNOT4,NPTX1,PCBP3,TREM2,RETREG1,MAPK7,MASP1,CPEB3,KDM4B,LHPP,RPGRIP1L,PCDHGA10,LMF1,PRDM10,TIGD6" Drug 7473_UP Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMPH,BIN1,CDC42BPA,APOC1,MARK4,SYNJ1,USP2,ARHGEF10,ARHGEF4,CDON,RCAN1,EGFR,MRNIP,FAM198B,FGF13,SCARA3,AFF2,LPAR4,IL6R,INPP1,MIA2,LYRM9,NF1,NPY,NPTX1,PALM,PLTP,MBOAT7,MAPK10,ZSCAN32,PTPRD,DPF2,RFX3,RGS3,RASA3,SLC11A1,TSNAXIP1,SYN2,SMG6,PCDHA6,HPS4" Drug 3483_DN Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APBB2,BCAS1,PPFIA3,ARRB2,BMP7,CFAP410,CAMK2G,FAM189A2,HOMER3,CRY2,LYPD1,SGSM2,DTNA,STX2,ZNF589,FHL1,SEMA4D,PRELID3A,CGREF1,SEPT9,INPP5K,GLYR1,CNTRL,KHK,MAP4,RETREG1,MBOAT7,ELOVL2,DCUN1D2,FBXO11,LIMCH1,ZBTB43,THSD1,ELOVL4,ANKRD12,SIK3,BEX4,ZKSCAN5,LMF1,MAP3K12,MPPE1" Drug 3218_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADD2,KIAA1324,FAM135A,APAF1,CFLAR,SYNJ1,CA4,HIP1R,RHBDL1,ARHGEF2,CRMP1,PHF14,CYBB,SPOCK2,ARMCX2,ERCC2,FHL1,DISC1,GCNT2,ADAMTS13,ITPKB,MATN3,MYCN,CNOT4,PCBP3,CDK18,PLCB2,LRP12,NKAIN1,RASGRF1,RGS4,SALL1,SLA,UNC5B,CDK19,ATP10B,DOCK9,TMEM121,UCHL1,CLIP2,NT5M" Drug 3609_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,BIN1,GAS7,ALDH7A1,BMP7,SCAPER,B4GALT6,STOML1,GREB1,DBT,FEM1B,FCF1,ZNF589,FGFR1,PRELID3A,GAD1,MALT1,GSN,IL6R,INPP5B,JAK2,KCNJ5,KPNA5,IPO5,TM6SF1,MMP16,ADAM22,RELN,RGS12,KCTD17,KCNIP1,BTBD7,COA1,TBCEL,ZKSCAN5,PLPPR2,WIPF1,ZFP37,EMSY,URM1,ITM2C" Drug 4171_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BEGAIN,APC,SEMA4G,N4BP2L1,CFLAR,BAIAP3,CAMK2B,LDB2,CDH2,CSF1,ARHGEF10,CNTNAP2,DAPK1,BRINP1,EDN1,C3orf18,F5,FGFR3,AFF2,DCTN2,OGA,GNAL,GNAO1,GRIK5,MID1,NPR2,NTRK3,PLCD1,PPP5C,MAPK7,PTPRB,KLHDC8A,EMID1,PKNOX2,SLC8A1,SLC11A1,OGDHL,NMNAT2,PEG10,PHLDB1,SLC17A7" Drug 5644_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,FGD2,CDC14B,PRX,RGS20,CDK13,CA4,CACNB4,ARHGEF1,CPS1,CREM,DZIP3,PHF14,ARHGEF4,PPP6R2,MAML1,EDN1,EDNRA,DLC1,ZNF589,FGF13,RUNDC3A,BTN2A1,MID1,MYCN,NTRK2,PALM,PRKCB,PTCH1,SH3GL3,KIF13A,RBM34,ATP10B,JMJD6,ZEB1,HEY1,R3HDM1,FLRT2,VSNL1,ZNF142,JPH3" Drug 1690_UP Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADGRB2,CFLAR,MTMR3,CACNA1I,CRLF1,PICK1,SH2B1,JAKMIP2,MFAP3L,RCAN1,EDNRA,EDNRB,DCTN2,DISC1,SRCAP,GNG4,GRB10,NXPH3,JAK2,MAN2A2,MBD1,KITLG,ADAM22,ZNF862,NACA,NFYA,CNOT4,NPR2,CDK18,MBOAT7,PPP5C,NKAIN1,TCP11L1,SUPT20H,FNDC3A,KDM4C,PLCB1,EXOC7,VIPR2,ST7,GAN" Drug 6476_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ACHE,NDRG2,ADORA1,SLC4A4,ATP2B2,NRP2,CFLAR,SCAPER,SGCE,LDLRAD4,HAP1,CHN2,SULT4A1,AATK,VCAN,RASL12,FAM198B,CORO2B,CAMKK2,VSIG4,ICA1,JAK2,KCNH2,MEF2C,ADAM22,MYCN,MINDY2,ZSCAN2,GSTCD,TCP11L1,KCNIP1,PPP4R3A,COA1,ATP10B,SS18,PLCB1,SYT5,DICER1,TRO,WIPF1,SLC30A3" Drug 4001_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,NDRG2,ADD2,MTUS1,PPFIA3,PPP4R4,HAP1,CBS,LDB2,NRXN3,TPP1,FAM189A2,VAX2,RIMS2,DTNA,TENM1,ING4,TNK2,ETV1,PTK2B,DLC1,SRCAP,KIFC3,AFF1,MMP16,MSR1,NTRK3,PCDH9,PDE4A,RETREG1,PTPRN2,RGS12,KCNIP1,ZNF334,ZHX3,SPTAN1,EXOC7,TPM1,TUBB1,ZNF24,PHTF2" Drug 6716_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADORA2A,BEGAIN,AMPH,N4BP2L1,BACH1,RGS11,RUNX1T1,CD86,CACNA2D2,IPCEF1,PHF14,DAPK3,RASGRP2,CORO2B,FGFR1,HPCAL4,SRCAP,GRIK5,SOX21,MAPT,NPR2,PDE4B,PPP1R1A,ZFP30,PKNOX2,CXXC4,IZUMO4,HECW1,SPTB,ARC,TACR1,ADGRL3,PCDHGA10,PCDHA5,TIMP4,TPM1,VIPR2,VLDLR,REEP1,NLRP3,GAN" Drug 5390_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMPD3,GAS7,PLA2G4C,CHRD,CFLAR,KSR1,GYG2,CHN2,SULT4A1,AKAP7,COL9A3,CYBB,SPOCK2,GSDME,TMCC2,COQ7,APC2,FGF12,FHL1,SRCAP,GLYR1,PCLO,RASSF8,KCNJ5,MAP2,ZNF862,NOVA1,PDE4B,PLCD1,LRP12,PTN,PTPRH,CCDC40,RGS4,MRAS,SLA,SLC2A5,PKNOX2,SAMSN1,SZT2,CABIN1" Drug 4113_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SYN3,NDRG2,N4BP2L1,CACNA2D1,CBFA2T2,FAM149A,WHRN,COL9A3,CRY2,AATK,RIMS2,SPOCK3,HIPK3,PLXNC1,RCAN2,EPHB1,PTK2B,GAD1,GFER,GUCY1A1,VSIG4,ICA1,MSR1,NNAT,NPTX1,OGG1,ENPP2,PFKFB2,CEP41,KLHDC8A,RPS6KA2,SH3BP2,SLC2A5,FAM214B,SLC11A1,SMARCD3,LIMCH1,KIAA1107,CHST5,SLC17A7,ITM2C" Drug 3895_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,SCAPER,CFAP410,CAMK2B,CAMK2G,KYAT1,PLEKHB1,B4GALT6,PICK1,WHRN,NECTIN3,SH2B1,CRY2,NCOR2,SOCS5,GPRASP1,ZNF804A,DMPK,KAT8,ZNF589,DISC1,SRCAP,GHR,RUNDC3A,STON1,IL6ST,ITPKB,MMP16,MMP17,ADAM22,ZNF862,NF1,CCDC40,LIMCH1,IQSEC2,VPS13A,SLC44A1,THRA,PARD3,PLPPR2,VIPR2" Drug 5013_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NME5,CDK10,ARRB1,SLC4A4,CFLAR,SYNJ2,CA12,AKAP7,ABCG1,DZIP3,RIMS2,SEZ6L2,PRELID3A,INPP5K,SRCAP,RAB30,GNG4,PCLO,AGBL5,INPP5B,KCNF1,LMO2,MAPT,TM6SF1,MSI1,ZNF862,PLEC,RAD51D,CPEB3,EPN2,FAM214B,LIMCH1,FNBP1,CLSTN2,MCF2L,OBSL1,NSD1,CRTC1,CABIN1,GDPD5,EPM2A" Drug 2250_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NME5,C1QTNF1,AMH,PRX,SCAPER,BAIAP3,RAB28,QKI,AATK,CSF1,DCAF4,SPOCK2,DTNA,EDNRA,VPS13B,ERCC2,NCALD,DLC1,OLFM1,FHL1,AGAP2,ATXN2L,KCNQ3,MAP4,MGAT3,NF1,P2RY1,PCDH9,DCHS2,ZMAT4,RGS12,SUPT20H,TRA2B,LIMS2,PKNOX2,SP4,TROVE2,ARC,KIAA1107,PCDHA5,CABIN1" Drug 6636_UP Harpagoside [19210-12-9]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,APBB2,ATP6V0A1,ADGRB2,RGS9,SYNJ1,MTMR3,MYRF,HAP1,MFAP3L,DTNA,EDN1,SEMA3D,F5,REEP2,FGF1,ERAP1,CSDC2,GNG4,SMAD9,MMP16,MSR1,NELL2,ENPP2,RETREG1,CNNM2,ELOVL2,PTPRB,C1orf54,EMID1,PEX26,IZUMO4,SPTB,CDK19,ATP10B,PHLDB1,ICAM5,RIMBP2,AMACR,LAT2,KCNAB1" Drug 4064_UP Corticosterone [50-22-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,AGT,ADGRF5,ATP2B2,GYG2,CAMK2B,ENTPD2,CHN2,TAOK2,PHF14,SEC14L5,SPOCK3,HS3ST2,ING4,LRRC17,RASGRP2,ZNF391,HPCAL4,AGAP2,PRELID3A,DISC1,SRCAP,GNAO1,SPACA9,CACFD1,ELOVL5,LAMA2,MARK1,MATK,NF1,NPTX1,NPTX2,NTRK2,CCDC40,CNKSR2,ZNF334,IZUMO4,RBM26,ASTN2,TACR1,MCF2L" Drug 3281_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ALCAM,SRPX,ALK,AMT,APLP1,ARRB1,CAMK2G,PLEKHB1,RAB28,CSF1R,LRIG1,FAM169A,TBC1D5,FCF1,EPB41L2,ERCC2,ZNF589,TPK1,ARFIP1,GPD2,TJAP1,JAK2,KIF2A,MSI1,NEK1,NF1,SLC11A2,PRKAR1B,RGS12,RASA3,FERMT1,ANKRD6,PREX2,ZKSCAN3,ELOVL4,VPS13A,PLCB1,CRTC1,SLC44A1,CDK20,TRIO" Drug 7273_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "MTUS1,APOC1,PPP4R4,CDK13,NRP2,KRIT1,SCARB1,RAB28,NRXN3,QKI,ARMC8,VCAN,CNTNAP2,DZIP3,HDAC9,DBT,RUSC2,DYNC1I1,DTNA,CNNM1,FAM13A,PLXNC1,CDKL3,ST3GAL6,GLYR1,FAM69A,NFYA,OPRL1,PALM,PTX3,NCBP3,PPP4R3A,KDM4B,DIP2A,FBXW11,ZEB1,TK2,RUNDC3B,ZNF711,NAV3,PHTF2" Drug 6450_DN Flucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AP2A2,AK2,SEMA6A,SRPX,AMH,AMPD3,ADAM15,SYNJ2,CAMK2B,ARHGAP33,PLAA,ARMC8,LRIG1,CNTNAP2,APPL1,DOCK4,LYPD1,DTNA,OPTN,PLXNC1,PRELID3A,INPP5K,TXNL4A,MSL3,GPER1,CACFD1,INPP5B,IPO5,NPTX1,P2RY1,SMOX,WDR25,ZSCAN32,TROVE2,CEP68,TNS2,PLPPR2,VGF,KCNK12,HPS4,RNF170" Drug 3134_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ACTN1,CDC42BPA,SEMA4G,CAPN3,LHX2,WHRN,CREM,NCOR2,PDE4DIP,RUSC2,SPOCK3,EPHB1,ETV1,FGFR1,PDLIM5,FYB1,ALDH1L1,POLL,KCNMB4,GRM8,PADI2,TJAP1,KCNN1,MAP4,TAGLN3,NNAT,PFKFB2,EPB41L4B,POLG,PTPRN2,FAM102A,SNCA,ATP10B,TBCEL,CUX2,RPGRIP1L,SZT2,CRTC1,THRA,VIPR2,ADAMTS9" Drug 2768_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,ADORA1,KCNAB2,APOC1,PDE8B,MARK4,SLC4A4,SYNJ2,CACNA1I,BAIAP3,ARHGAP33,HOMER3,CSNK1E,ARHGEF4,EDNRA,ING4,KHDRBS3,GFER,LILRA2,GRIK5,KCNJ5,MAP4,MATK,PPP5C,PRKAR1B,RELN,ZDHHC14,RTN1,ASAP3,PKNOX2,ARHGEF40,KIF13A,HECW1,IQSEC2,EXOC7,TRIO,HIRA,FAM155A,LMF1,ZFP37,KAT6A" Drug 6302_UP Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "PPFIA3,CALB2,RUNX1T1,SCARB1,SYNGR3,TAOK2,RAB33A,VCAN,PDE4DIP,MAML1,SPOCK3,CELSR3,ELN,COQ7,EZH1,ABCA8,ZNF589,FYN,TRAF3IP2,SIGLEC8,INPP5K,ZNF276,IL6ST,INPP5B,SMAD1,MGAT3,MT1M,NFYA,NDUFS7,PTCH1,RGS12,SH3BP2,EPN2,CCDC88A,SLC9A5,KANK1,EXOC7,ZEB1,VGF,ZNF225,NT5M" Drug 4253_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SEMA6A,LTBP4,SEMA7A,PPP4R4,ZSCAN18,N4BP2L1,BACH1,SYNJ1,CFAP410,CBS,FOXN3,ARHGAP22,AATK,CNTNAP2,TENM1,COQ7,EPHB1,DCTN2,FYB1,NEU3,IL6ST,KIT,NPTX1,NRCAM,NTRK3,PCDH9,FXYD1,MAPK3,SH3BP2,SPP1,SPTB,DDN,ARHGEF9,CRTC1,AP4E1,TUBB1,KCNK12,SLC17A7,HRASLS,KAT6A,DPF3" Drug 6557_DN AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "PPP4R4,ADAM15,CAMK2B,ARHGAP33,NRXN3,RAB26,OSBPL3,CNTNAP2,RUSC2,SPOCK3,DPH1,CNNM1,SCML2,FGF1,FGFR1,ANKFY1,PDLIM5,MSL3,STON1,HSF2,IL6ST,INPP5B,MIA2,ADAM22,MSR1,NFIX,KCTD15,PPP5C,KBTBD4,BTBD7,SNCA,TMCC1,FNBP1,IZUMO4,SPTAN1,COBL,FBXW11,TMEM121,RUNDC3B,UBE3B,KAT6A" Drug 3450_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AK2,KCNAB2,APBB2,GAS7,APLP1,PPFIA3,ATP6V0A1,GYG2,USP2,CACNA2D2,SRSF11,CLCN3,SH2B1,JAKMIP2,MFAP3L,SUGP2,C3orf18,ZNF589,FGFR1,SEMA4D,SRCAP,GPD1,DIDO1,HNMT,KCNH2,MAP4,NFYA,NTRK2,MINDY2,PPP5C,PRKAR1B,FAM214B,COA1,SPTAN1,CDK19,ZBTB43,ATP10B,PLCB1,TRIO,SLC30A3,KCNAB1" Drug 7294_DN Imipenem [74431-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BRAP,PPFIA3,SLC4A4,STX16,BID,ST3GAL5,SCAPER,HIP1R,CHN2,BAG4,ENTPD4,APPL1,CINP,COPS8,MAPT,MITF,NPR2,PLCD1,POLG,PPP5C,KIRREL1,SLC22A4,LIMCH1,DOP1A,SEPT8,ARHGEF9,SIN3B,ZNF34,TMPO,PARD3,SSBP2,ZKSCAN5,HIRA,PLPPR2,WNT7A,XRCC4,NDRG4,SPHK2,MAP3K12,EVI5,FZD3" Drug 6250_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "TRMT9B,AMPD3,SLC4A4,CACNA1A,CAMK2G,QKI,CTH,GIT2,ZNF589,BAIAP2,FHL1,ATP2C1,FYB1,TDRKH,GRIN2C,MAP4,AFF1,ADAM22,OPRL1,PLCD1,POLG,MAPK10,ZCWPW1,KCTD17,GSTCD,SH3BP2,FBXO11,SYBU,ANKRD6,PPP4R3A,ZSWIM8,ZNF423,SPTAN1,EXOC7,AP4E1,TK2,RUNDC3B,ZKSCAN5,KCNK12,ADAMTS9,TIGD6" Drug 3017_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,ABHD6,MTUS1,PKP4,PRX,ARHGDIG,RIPK1,RGS11,CACNA1G,MYRF,CACNA2D2,AKAP6,SNPH,SPOCK3,EXOG,MAMLD1,EGR3,CALCRL,FER,BAIAP2,GAD1,GRIK5,SCIN,KHK,LSAMP,MMP16,NTRK2,CLDN11,PDE1C,GPR173,SLC25A23,MAPK10,PTPN13,RASGRF1,SCN8A,LIMS2,TRIM2,PHF24,TRPS1,SSBP2,ACTR3B" Drug 4818_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,NDRG2,C1QTNF1,SEMA6A,ARNTL,BAIAP3,SPAG9,CBFA2T2,BAG4,ENTPD4,VCAN,RUSC2,LYPD1,DMPK,DTNA,EDNRA,HIPK3,ING4,KAT8,AGAP2,FLNC,ANKFY1,MALT1,GLYR1,GRB10,RASSF8,LSS,MX1,NFYA,NPTX1,C1orf54,SUSD4,TCP11L1,STUM,SH3BGR,SMARCA4,ZHX3,EXOC7,KIAA1107,PCDHA6,VAV1" Drug 2042_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADORA1,LTBP4,PRX,PDE8B,CA12,CACNA1A,CALB2,CACNA2D2,STOML1,CNTFR,IQCK,CTH,TMCC2,TNK2,SRPK3,ELN,GNAO1,SPACA9,CACFD1,PRDM5,NXPH3,TJAP1,KCNF1,LAMA2,MBP,MITF,GIT1,SAMD14,DUSP26,PPARA,CEP41,RGS12,RNASE1,RXRA,LIMS2,FAM214B,SLC6A11,SPTB,PHLDB1,SYN2,VGF" Drug 2839_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,LTBP4,BIN1,APBB2,APOC1,CDK10,SLC2A11,BMP7,CDH2,WHRN,PPP6R2,SPOCK2,MFAP3L,DTNB,C3orf18,VPS13B,FGFR1,GABRG2,SIGLEC8,SRCAP,MSL3,GPR37,CACFD1,GSN,IL6ST,INPP5B,KCNH2,MITF,MYO9A,NF1,PGAM2,RGS12,FRMPD1,ASAP3,LIMCH1,SOX3,ARHGAP26,DICER1,PIK3R5,VLDLR,KCNAB1" Drug 3248_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,NME5,AK2,SEMA6A,PPFIA3,ATP6V0A1,CAMK2G,RCBTB2,PICK1,CNTFR,NCOR2,SPOCK2,RUSC2,TMCC2,FCF1,CNNM1,VPS13B,FAM198B,FGF12,ALDH1L1,STON1,GRIK5,BTN2A1,KCNN2,LIG4,SMAD1,ZNF862,PFKFB2,PLCD1,SLC25A23,TRIM68,SLC9A5,LIMCH1,TROVE2,ELOVL4,EXOC7,WSCD1,CHST8,ZNF34,UPF3A,GDPD5" Drug 631_UP benserazide hydrochloride; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SPOP,CDC42BPA,CDC14B,BCL7A,BMP7,SCARB1,CSNK1G3,KIAA0753,EPB41L2,FGFR1,ATP2C1,GNAL,RBPJ,IL6ST,NF1,NNAT,PDE4D,PDPK1,PPP3CA,RAP1GDS1,ROGDI,PCMTD2,FERMT1,FUZ,SLC11A1,KBTBD4,SMARCC2,MAPKBP1,TMCC1,FNBP1,CAMTA2,ITPRID2,ST5,PRRC2C,MLST8,TRIM2,ZMAT3,SMUG1,TSC1,UBE3A,HPS4" Drug 3417_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,AP2A2,MARCH3,EIF4G3,CFLAR,SOCS6,QKI,LRIG1,CSNK1E,DBT,EZH1,CGREF1,GRB10,LIG4,MAP4,NFYA,CCSER2,SMIM7,MBOAT7,POLR2F,WDR25,NKAIN1,ZCWPW1,NCBP3,TRAPPC13,BTBD3,EPN2,ARFGAP1,ZSWIM8,TSPYL2,CLASP2,TROVE2,EXOC7,IQCE,NR2C2,TRIO,HIRA,ZNF142,REEP1,MPPE1,RNF170" Drug 3525_UP Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NME5,ALCAM,CDC42BPA,APBA2,ATP1A3,HIP1R,ARHGEF1,CBFA2T2,KCNAB3,CPS1,ENTPD4,AATK,RIMS2,SPOCK2,ELN,C3orf18,IQCG,FYB1,SIGLEC8,SEPT9,INPP5K,GATM,MALT1,ICA1,AFF1,ADAM22,TAGLN3,SAMD9,KHDRBS2,RGS12,TCP11L1,NLGN1,FAM214B,SLC14A1,ZEB1,PCDHGA10,CRTC1,DNAH7,TNS1,LMF1,LAT2" Drug 1298_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APBB2,ARNTL,MARK4,NCOA1,N4BP2L1,CFLAR,ARHGEF7,C5,HOMER3,RNF14,TM9SF4,DBT,ERCC2,ERAP1,ARFIP1,HTATSF1,LPAR4,MUM1,HSF2,ZNF862,SETD4,ZNF426,MINDY2,MAPK3,PTK2,CLIP1,ATXN2,AMBRA1,SLC2A5,SIRT2,CCDC88A,BTBD7,KDM4C,DBNDD2,ZBTB43,NXT2,TBL1X,PARD3,TNS1,TRPS1,XRCC4" Drug 2453_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,PPFIA3,RIPK1,BACH1,CFLAR,CACNA2D1,CHN2,HOMER3,COL9A3,CLOCK,PDE4DIP,DTNB,EIF1,DLC1,OLFM1,FGFR1,ANKFY1,KHDRBS3,OGA,TRAF3IP2,SIGLEC8,GNG4,KIF5A,KPNA5,MAP4,AFF1,PDE4D,PFKFB4,CCSER2,PLCD1,BCAS3,WDR25,GAL3ST4,ZC3H13,LHPP,AP4E1,GPR161,TLR4,TPM1,KCNAB1,GJC2" Drug 3798_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "LGR5,CD86,ARHGAP33,CACNA2D2,TPP1,CNTFR,AKAP6,MYRIP,ABCG1,ERC2,BRINP1,DBT,DMPK,DTNB,EDN3,NRN1,HPCAL4,FYB1,GDF9,GPD1,PRUNE2,LILRA2,GRM2,KCNH2,KCNJ5,KITLG,MMP17,NTRK2,LRRN3,PRPH,ZSCAN32,PTPRB,ZMAT4,RGS12,RNASEL,SEMA6D,SPTB,OBSL1,LAT2,FAM13C,NLRP3" Drug 4370_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "RALGAPA1,AP2A2,SEMA6A,AMPD3,APBA2,APBB2,APC,PPP4R4,SLC2A11,GYG2,CACNA1I,WHRN,NECTIN3,CSF1,FAM169A,IGSF6,TRAF3IP2,GAD1,MSL3,GNG4,GRIK5,ICA1,IL6ST,KIT,KITLG,MMP16,NF1,NTRK2,RETREG1,MBOAT7,PTN,ZDHHC14,ZFHX4,TCP11L1,PLCB1,ZEB1,CRTC1,VGF,KCNAB1,ITM2C,SMIM8" Drug 4964_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "APBA2,CDK13,DNAH17,MARK4,GYG2,BAIAP3,LDLRAD4,CAMK2B,RGN,CHRNA4,NRXN3,CSF1,OSBPL3,RIMS2,EIF4G2,F5,ZNF589,FGFR1,KHDRBS3,GABRB3,ALDH1L1,RUNDC3A,LPAR4,SPACA9,C2orf72,KCNH2,ADAM22,FXYD7,RETREG1,MAPK10,ZFHX4,CARF,ASAP3,FAM214B,TROVE2,WSCD1,CRTC1,PCDHA5,LAT2,KCNK12,SLC17A7" Drug 1296_UP Androsterone [53-41-8]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,NDRG3,MTUS1,APOC1,CDK10,SLC4A4,CFAP410,HIP1R,DGKI,IQCK,SIPA1L1,PDE4DIP,SGSM2,EIF1,IQCG,FLT1,SRCAP,INPP5B,LSS,N6AMT1,ZNF862,NFYA,PDE4B,PRKAB2,PTN,ZNF493,SEC14L1,FNDC3A,SLC9A5,ZNF423,SPTB,SS18,STXBP1,ADGRL3,SMG6,SIN3B,TIAM1,TNS1,SMUG1,PDSS2,EPM2A" Drug 5865_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "BIN1,EP400,MARK4,CFLAR,CNOT8,TAOK2,CSF1,CNTNAP2,ZNF337,GIT2,DBT,RHOBTB1,TMCC2,DYNC1I1,MRNIP,EPB41L2,TRMO,HTATSF1,HNMT,JAK2,MEIS1,SLC25A23,ELOVL2,RIPOR1,SH3TC2,SH3BP2,LIMS2,SMARCA4,SPATA7,ZBTB43,SS18,ARHGEF9,PDLIM2,IQCE,FBXW11,ZNF34,UBTF,SPHK2,ZFAND5,GDPD5,NAV3" Drug 1327_UP Piperine [94-62-2]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "MTUS1,OSBPL1A,GAS7,BCAS1,ARRB1,ATP6V0A1,MYRF,SCARB1,HOMER3,CSNK1E,VCAN,CYBB,DOCK4,KIAA0586,NR1D2,RASGRP2,PTK2B,CAMKK2,DISC1,SEPT9,GLYR1,MAN1B1,IRF8,NF1,SLC11A2,P2RX7,PDE4B,SNRK,ZCWPW1,RNH1,DGLUCY,SH3BP2,SMARCA4,SMARCC2,SPTAN1,ZBTB43,STX1A,TCF4,SZT2,PLPPR2,LAMP5" Drug 2170_UP Solasodine [126-17-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SYN3,CDC42BPA,DDO,BMP7,CACNA1I,C5,CFAP410,CBFA2T2,SYNGR3,CACNA2D2,TAOK2,ABI3BP,CRY2,ABCG1,ELN,NCALD,FOXF2,AGAP2,PDLIM5,PRELID3A,SIGLEC8,SEPT9,KCNMB4,GNAO1,GSN,MAP4,MEF2C,ADAM22,MX1,MYCN,P2RY1,TREM2,SLC25A23,MTRF1L,SUSD4,PREX2,PKNOX2,WSCD1,DOCK9,TPM1,FAM155A" Drug 2154_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABR,BMP7,LDLRAD4,HOMER3,CSNK1E,ZNF337,TBC1D5,KIAA0586,DPH1,HIPK3,FCF1,ING4,TUBD1,AGAP2,FLT1,GATM,ADAM28,GLYR1,CACFD1,KCNJ5,MX1,OGG1,NLE1,PLEC,SLC25A23,PLTP,PMP22,GALNT10,SH3BP2,SLC11A1,SP4,IZUMO4,KDM4C,SS18,PLCB1,DNMBP,TCF4,PARD3,REEP1,URM1,ST7" Drug 642_DN 6-thioguanine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMPD3,EPB41L5,GAS7,PPFIA3,NCOA1,NAE1,BAIAP3,KALRN,RUNX1T1,KRIT1,ARHGAP33,OPTN,FAM13A,SUGP2,KCTD3,PLEKHA1,SRPK3,ETV1,ALDH1L1,RNFT2,PAXBP1,MAP4,MATK,MBNL1,NELL2,NPR2,NPTX1,NTRK3,STRN3,MAPK3,STUM,SH3BP2,AMBRA1,MYCBP2,ZC3H13,SPART,PHLDB1,KLHL7,GDPD5,SLC17A7,GAN" Drug 4345_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ALCAM,APOC1,PROM1,CFAP410,CDH2,RCBTB2,VCAN,DAPK1,ARMCX2,DTNA,FRY,C3orf18,NSG1,CSDC2,GNAL,HLF,ELOVL5,C2orf72,ITGAM,KCNB1,KCNH2,LAMA2,NOVA2,P2RY1,CDK18,TMOD2,PGAM2,MAPK7,PTH1R,RASGRF1,SH3BP2,CNKSR2,HECW1,ZNF423,TBCEL,R3HDM1,LAT2,SLC17A7,PLSCR4,NLRP3,DPF3" Drug 4701_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "NDRG2,NME5,EPB41L5,SEMA4G,ARNTL,ARRB1,SLC4A4,CFAP410,QKI,AKAP6,CSF1,CNTNAP2,SPOCK2,GIT2,DTNA,HIPK3,ING4,FGFR3,AGAP2,ANKFY1,GRB10,KCNH2,KITLG,MSI1,C19orf57,LRRN3,PPP5C,ELOVL2,RGS12,NUDT11,KCNIP1,SLC9A5,DOP1A,CLSTN2,PHLDB1,PCDHA6,CHST5,FLRT2,VGF,KCNAB1,UBE3B" Drug 7023_UP Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "KCNAB2,APBB2,PPFIA3,ARHGDIG,PDE8B,DNAH17,SCAPER,BAIAP3,CACNB4,CAMK2G,GPRASP1,DAPK3,PHF20L1,MRNIP,PCOLCE2,EPB41L2,PIPOX,FAM198B,TPK1,GPER1,GRIK5,INPP5B,MGAT3,MKLN1,SETD4,ZDHHC14,RFX2,EXD2,FBXW7,SAFB,SBF1,PREX2,PEX26,CDK5RAP2,SNCA,STX1A,R3HDM1,FAM155A,ZNF45,SLC30A3,ST7" Drug 6801_DN Pyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AP2A2,NME5,PPFIA3,PLA2G4C,ALDH7A1,UBE2L6,BAG4,CREM,CSF1,SOCS5,CTH,MFAP3L,C2CD2L,EDNRA,HIPK3,NCALD,ANKMY1,FAM198B,SEMA4D,NOP56,PRELID3A,SEPT9,RAB30,CNTRL,MUM1,NEK1,NF1,NPR2,SMIM7,ZSCAN32,TMEM231,CCDC25,SH3BP2,LIMCH1,MAPKBP1,ELOVL4,PLCB1,ASTN2,VGF,EMSY,ST7" Drug 4675_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,LTBP4,GAS7,BACH1,ADGRB2,NRP2,CFLAR,CBS,KCNAB3,CSF1R,PLPPR4,DRP2,CELSR3,RASGRP2,CAMKK2,USP19,RUNDC3A,BACH2,KCNF1,LSS,MIA2,MMP16,GIT1,ADAM22,MSR1,P2RY13,ELOVL2,PTN,ACSS3,ZMAT4,PNMA8A,SCN2B,KANSL3,KDM4B,ZHX3,CDK19,PHLDB1,SYN2,TUBB1,KCNK12,ZNF24" Drug 6178_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "AMPH,SLC4A4,MPDZ,HIP1R,ABCG1,SIPA1L1,PDE4DIP,SNPH,SPOCK2,ECM2,SEZ6L2,MBNL2,TNK2,MRNIP,TMEM8B,SIGLEC8,SPACA9,KCNB1,KIT,SAMD14,MYO7A,NF1,PAX6,PDE4B,MBOAT7,VPS13C,PTPRN2,HSPA4L,SH3BP2,FERMT1,SLC11A1,KDM4B,ATP10B,SS18,TCF4,DICER1,LMF1,ZBTB38,SLC17A7,GJC2,DPF3" Drug 482_UP celecoxib; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ALK,RASL11B,BMP7,SYNJ2,MTMR3,HOMER3,PCYT1B,HAPLN1,INTS1,E2F5,TNK2,RASL12,OLFM1,GABRG2,CYP46A1,LUZP2,LILRA2,AP4S1,RASSF8,PADI2,MAN1B1,ATXN2L,KCNJ5,MSR1,NNAT,SETD4,GPR173,LRP12,LRRN3,NUDT11,ATXN7,SLA,SPART,ARHGEF9,TCF4,SATB2,ZEB1,RPRM,KCNK12,EVI5,VPS35L" Drug 2531_UP Butamben [94-25-7]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "C1QTNF3,APAF1,APBB2,CASK,CLGN,B4GALT6,ARHGEF10,DAPK3,GSDME,CNNM1,MBNL2,ING4,TNK2,EIF1,COQ7,STX2,FER,SCARA3,SIGLEC8,INPP5K,NCKAP1L,ATXN2L,NINJ2,P2RY1,PDE4D,PPARA,PPP5C,MAPK7,MAPK10,RIPOR1,TCP11L1,MAP6D1,SEC14L1,RASA3,SH3BGR,EPN2,SLC11A1,SPTAN1,TRIO,TRPS1,SENP7" Drug 5814_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASPHD1,ACTN1,C1QTNF3,AMPD3,GAS7,KIF1A,CFLAR,VCAN,PDE4DIP,ARHGAP24,DCAF8,ZNF337,TM9SF4,GIT2,KIAA0753,C2CD2L,DTNA,OPTN,AASS,MRNIP,FGFR3,FYN,LPAR4,SPACA9,GRIK5,PADI2,HSF2,IRF8,MIA2,TAGLN3,PRODH,SBF1,CSRNP3,ZNF334,ZHX3,KDM4C,ELOVL4,TBCEL,TRIM2,TK2,NT5M" Drug 1496_UP Minoxidil [38304-91-5]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "SYN3,ALCAM,APOC1,BCAS1,ATP6V0A1,CFLAR,ST3GAL5,CA12,CNTFR,FAM169A,PHF14,RASSF2,MFAP3L,LYPD1,TMCC2,ZNF589,FGF12,BAIAP2,AHDC1,RAB30,GRIK5,TJAP1,INPP5B,KCNN1,MAP4,MBD1,TM6SF1,MMP16,ZNF862,NF1,RETREG1,TSNAXIP1,SPP1,ZC3H13,STX1A,SYT5,CRTC1,TRIO,RUNDC3B,ZNF45,SPHK2" Drug 4470_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADORA1,AGT,ALK,SEMA7A,APAF1,GAS7,ATP6V0A1,NRP2,GYG2,LDLRAD4,THSD7A,CHN2,TAOK2,STOML1,COL9A3,CHRDL1,EDNRB,MRNIP,FYN,ICA1,LAMA2,MYT1,P2RY1,PCDHGC3,SMOX,PURG,POU6F1,PTPRN2,RFX2,RGS12,TCP11L1,HKDC1,ZNF334,ZHX3,PLCB1,MCF2L,SMG6,PCDHGA10,PCDHA5,DNAH7,LAT2" Drug 1851_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,CDC42BPA,PPFIA4,APC,APOC1,KIF1A,ADAM23,MTMR3,PLAA,AKAP7,IQCK,NRG2,CSF1,GSDME,PLXNC1,MRNIP,EPB41L2,RRAGB,AFF2,DCTN2,SRCAP,GPD2,SPACA9,NF1,PLCD1,PMP22,PTPRN2,MAP6D1,RPS20,RASA3,SH3BGR,TMCC1,DOP1A,DBNDD2,TSPYL2,CEP68,STX1A,DNMBP,SLC44A1,PARD3,PHTF2" Drug 4147_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ADGRF5,BEGAIN,AMH,CDK13,ATP2B2,CFLAR,CACNA1I,RUNX1T1,CLDN10,EPS15L1,AKAP7,VCAN,DAPK1,HS3ST2,DYNC1I1,RCAN2,SPEG,OGA,PRUNE2,KCNB1,LIFR,TAGLN3,NNAT,NOVA2,NTRK3,PSD,SLC2A5,PKNOX2,FAIM2,DOK5,LMO3,ATP10B,SYN2,WSCD1,PCDHGA10,SLC35G2,DNAH7,CLIP2,LAT2,SLC30A3,SMIM8" Drug 6520_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "LTBP4,KCNAB2,APOC1,ARHGDIG,ATP2B2,RGS11,RUNX1T1,QKI,CSF1,GREB1,RASSF2,SPOCK2,ARMCX2,DTNA,ERCC2,DLC1,FGFR1,OGA,GALC,SOX21,KCNJ5,PDE4D,MTRF1L,CCDC40,ZMAT4,RGS3,RGS12,GSTCD,TCP11L1,RPS6KA2,SEMA6D,MRAS,COA1,SMARCD3,HECW1,ARHGAP26,PHLDB1,PCDHGA10,VIPR2,ZNF711,SEMA3B" Drug 4752_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ASIC1,ABHD6,APBA2,CDK13,CCK,CDH2,EPS15L1,TPP1,NCOR2,ARHGEF10,CYBB,SPOCK2,TMCC2,EXOG,EDN1,EGR3,FGFR1,AGAP2,SIGLEC8,LYVE1,SYNPO,ICA1,KCNH2,SMAD1,MATK,MMP16,MPP2,NTRK2,PDE4B,PPARA,MAPK7,RGS12,ATP10B,PHLDB1,TACR1,TRIM2,THRA,LAT2,SLC30A3,EVI5,ITM2C" Drug 3839_DN Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.78E-05 1.00E+00 1.38E-03 1.56E-02 41 198 "ABHD6,NDRG2,ARRB1,SYNJ1,CA12,ARHGAP33,FOXN3,TAOK2,HOMER3,CSF1,LRIG1,DAPK3,LYPD1,DTNA,DUSP9,MBNL2,ELN,HSD17B14,COQ7,FAM198B,GFER,GLYR1,HTATSF1,LSS,ADAM22,NFYA,NPR2,RETREG1,SNRK,RGS3,TCP11L1,SEC14L1,SH3BP2,FNDC3A,SMARCA4,SOX3,TROVE2,NXT2,PARD3,MAP3K12,HPS4" Drug CID000002531 calmidazolium chloride Stitch 9.87E-05 1.00E+00 1.40E-03 1.57E-02 35 160 "ADCY5,ADCY6,ADCY8,ADORA2A,AGT,ATP2A2,ATP2B2,ALDH7A1,CACNA1A,CACNA1B,CACNA2D1,CALM1,CAMK2B,KRIT1,LRBA,MYL6B,HDAC4,DNAH9,PTK2B,CAMKK2,ATP2C1,MYLK2,KCNN1,KCNN3,P2RX7,PDE1C,PDE1B,ENPP2,PPP3CA,PPP3CC,PRKACB,PRKCB,PTK2,RNH1,CABIN1" Drug 1005_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.00E-04 1.00E+00 1.42E-03 1.59E-02 38 179 "OSBPL1A,BIN1,OGT,CFLAR,ST3GAL5,CAMK2G,PDE4DIP,GIT2,ARMCX2,RCAN1,DTNA,TOM1,FHL1,B4GALNT1,DIDO1,CACFD1,HLF,KCNN1,MPP2,NACA,NPR2,NUCB2,MORC4,HSPA4L,SGK1,SH3BGR,PPM1E,TSPYL2,POGZ,JMJD6,EXOC7,TRIM2,BHLHB9,WBP2,VLDLR,ZNF74,PHTF2,FXR1" Drug CID005310991 A-192621 Stitch 1.03E-04 1.00E+00 1.45E-03 1.63E-02 5 6 "EDN1,EDN3,EDNRA,EDNRB,ST8SIA2" Drug CID000042106 tiapamil Stitch 1.03E-04 1.00E+00 1.45E-03 1.63E-02 5 6 "CACNA2D1,DMD,ABCB1,PIK3C2A,SYNE1" Drug 4743_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "GAS7,MADD,CDK13,CFLAR,ST3GAL5,SYNJ2,GYG2,ARHGAP33,AKAP12,GREB1,DOCK4,DBT,DTNA,FCF1,MBNL2,ENO2,STX2,FGFR1,INPP5K,SRCAP,CNTRL,RNFT2,MAP4K5,HNMT,TJAP1,IL6ST,MIA2,MMP16,LRP12,NKAIN1,SLC25A36,ZNF821,COA1,LIMCH1,SS18,SZT2,ZNF34,HIRA,XRCC4,MPPE1" Drug 2219_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "SEMA7A,ADGRB2,CFLAR,CFAP410,CAMK2B,ASIC3,SULT4A1,RCHY1,CPS1,GREB1,ARHGAP24,RASSF2,DGKG,DAPK1,EDNRA,HIPK3,MBNL2,PLXNC1,TNK2,VPS13B,STX2,FHL1,OGA,MSL3,RASSF8,IL6ST,SMAD1,ENPP2,PLCD1,ZMAT4,RFX2,KCNIP1,SCN8A,TRA2B,ST6GAL1,ZBTB43,SZT2,KAT6B,VSNL1,NT5M" Drug 6513_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "AK2,GAS7,PLA2G4C,ADAM23,CFLAR,SLC16A4,CLGN,CHRNA4,HOMER3,GREB1,SPOCK2,BRINP1,DTNA,FHL1,AGAP2,GCNT2,GPR162,GNAO1,FERMT2,GRIN2C,SLC2A6,ATXN2L,TJAP1,MBD1,NEFM,PDE1C,MTRF1L,TRIM68,MRAS,PPP4R3A,SNAP25,HECW1,SMG6,TRIM2,PCDHGA10,DOCK9,SLC44A1,SLC30A3,PLSCR4,JPH3" Drug 2873_DN Imipenem [74431-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "SEMA6A,APOC1,CFLAR,BMP7,SCAPER,CBR1,SOCS6,ARMC8,PDE4DIP,ARHGEF4,PPP6R2,DAPK3,B3GAT3,DTNA,HIPK3,VPS13B,FGFR1,FAM49B,CACFD1,MAP4K5,IL6ST,KCNH2,MBD1,MPP2,GIT1,PLXNB1,MBOAT7,CNNM2,TMEM231,SLC25A36,CLIP1,SEC14L1,FNDC3A,SLC22A4,ASTN2,TBL1X,UBE3A,REEP1,EMSY,SEMA3B" Drug 4152_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "NDRG2,AMPD3,APLP1,CACNA1A,CAMK2B,FOXN3,SLIT2,CRY2,SNCAIP,DBN1,EDNRB,MBNL2,MRNIP,NEU3,ALDH1L1,GLYR1,GSN,ATXN2L,MYT1,NF1,CDK18,PLCD1,FSD1,NKAIN1,TCP11L1,ZNF821,FNDC3A,ABLIM3,LIMS2,SLC9A5,COA1,SNCA,KIF13A,PHLDB1,SYT5,TBCEL,TMEM121,TRPM2,SPHK2,MPPE1" Drug 4244_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "NME5,CDC42BPA,PKP4,APAF1,PPP4R4,SLC2A11,N4BP2L1,ADGRB3,ST3GAL5,HAP1,SULT4A1,AKAP12,HAPLN1,PDE4DIP,RIMS2,DAPK3,EPHB1,STX2,ETV1,DCTN2,PCDH17,LAMA2,MAN2A2,MARK1,TM6SF1,MT1M,NEFM,NPR2,MAPK3,MAPK10,GAL3ST4,DZIP1,ZNF334,ARC,DOCK9,OBSL1,ZFPM2,GPR161,HEY1,PLSCR4" Drug 4267_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "MTUS1,APBB2,APOC1,ADAM15,KRIT1,SRSF11,PDE4DIP,STX2,RRAGB,FCGRT,FYN,B4GALNT1,KCNMB4,RASSF8,AGFG1,IL6ST,FAM69A,INPP5B,NFIX,CNOT4,PIK3R1,STRN3,PRKAB2,RAD51D,RBBP6,REV3L,FBXW7,FBXO11,ZNF667,LIMCH1,CEP68,ARHGEF9,DICER1,PARD3,WIPF1,XRCC4,EVI5,KCNAB1,MPPE1,UBE3B" Drug 4311_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "NME5,CDK10,SRSF11,HOMER3,FCF1,IRAK4,ING4,BAIAP2,DENND2A,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,HNMT,AGFG1,IL6ST,KHK,MAP4,MEF2C,NFIX,STRN3,PID1,GSTCD,KIRREL1,CSRNP3,ASAP3,CCDC88A,KDM4B,TBCEL,TBL1X,DICER1,TMPO,PARD3,SSBP2,ZBTB38,HPS4,KCNAB1,KAT6A,FXR1" Drug 629_UP 2-propylpentanoic acid; Up 200; 1000uM; SKMEL5; HG-U133A Broad Institute CMAP Up 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "ADD2,NME5,ALCAM,CDC42BPA,MARK4,MTMR3,CA12,HIP1R,SPAG9,WHRN,TNK2,NRN1,SCML2,FGFR1,FHL1,ATP2C1,FYN,NEU3,PCDH17,FERMT2,TPPP,GRIK5,KCNH2,MARK1,MEF2C,GIT1,NFE2L2,PDPK1,RETREG1,GPSM2,PPP3CA,PRKACB,RBBP6,SEC14L1,SMARCC2,CDK19,ST5,ZMAT3,RPRM,SLC17A7" Drug 2081_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "ASIC1,ADD1,APOC1,MADD,SCAPER,LHX2,AKAP7,PDE4DIP,GPRASP1,EGFR,TUBD1,CINP,FAM49B,DISC1,SRCAP,COPS8,SLC2A6,MUM1,INPP5B,IPO5,MPP2,SETD4,OGG1,PDE4A,POLG,MAPK3,SH3BP2,BTBD7,SPTAN1,ELOVL4,ARHGEF9,EXOC7,TCF4,ZEB1,TSN,LMF1,ZBTB14,TFIP11,PHTF2,AAAS" Drug 3375_DN Ethaverine hydrochloride [985-13-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "ASIC1,AP2A2,APBB2,APLP1,PLA2G4C,HAP1,STOML1,GREB1,DMPK,DTNA,EGFR,ING4,CDKL3,OGA,ERAP1,SEPT9,GLYR1,GPR37,ELOVL5,ICA1,IL6R,IL6ST,ZNF862,PCDH9,STRN3,LRP12,POLG,PRKAR1B,MAPK10,PTPRO,ZFHX4,FBXW7,TCP11L1,FERMT1,PEX26,SNCA,TBCEL,ZKSCAN5,VGF,WIPF1" Drug 4487_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "SYNJ1,IL33,KRIT1,SCARB1,FOXN3,CHN2,PLEKHB1,B4GALT6,LHX2,CRY2,DZIP3,DBT,KIAA0753,TMCC2,EDIL3,FAM13A,ETV1,RRAGB,GPER1,GUCY1B1,NDP,NF1,SLC25A23,PTN,PTPRN2,QDPR,GSTCD,KIRREL1,FBXW7,ASAP3,FBXO11,PPP4R3A,TMCC1,CAMTA2,IQCE,DICER1,TMPO,HIRA,NDRG4,FZD3" Drug 1517_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-04 1.00E+00 1.45E-03 1.63E-02 40 192 "CDC14B,CFLAR,CAMK2G,KRIT1,CCNT1,CLCN3,DCAF8,DBT,DTNA,CNNM1,IRAK4,DENND4A,VPS26C,NOP56,FAM49B,GNG4,GPR37,KTN1,MMP16,NFYA,SLC11A2,PIK3R1,MBOAT7,RIPOR1,RNASEL,NEK11,SUPT20H,ZNF430,ZBTB43,POGZ,CEP68,TACC1,TRIO,RPRM,VGF,ZNF74,UPF3A,EVI5,FIP1L1,JMJD1C" Drug CID000008035 "2,5-hexanedione" Stitch 1.04E-04 1.00E+00 1.46E-03 1.64E-02 17 56 "ACHE,BCHE,APPL1,TUBD1,TUBB3,CINP,TUBA8,MAP2,KITLG,NEFM,NEFH,CLSTN2,ADHFE1,TUBB2A,TUBB1,TUBA1A,GAN" Drug 2007_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.47E-03 1.65E-02 37 173 "GAS7,ARNTL,DNAH17,SLC25A14,CD86,CD38,ARHGAP33,FOXN3,CHN2,CREM,SIPA1L1,PPP1R16B,DOCK4,FAM13A,ING4,FAM49B,GALC,MEF2C,PDE4B,PDE4D,GPSM2,SMOX,PTPRE,PTX3,RPS6KA2,SATB1,FAM214B,ARHGEF40,DOP1A,ZSWIM8,SPTAN1,CDK19,SAMSN1,STXBP1,PLCB1,EXOC7,FLRT2" Drug CID000004587 AC1NFC6P Stitch 1.05E-04 1.00E+00 1.47E-03 1.66E-02 33 148 "PCDH10,MYOM1,GPC2,CBS,GAL3ST1,PLCXD3,FGFR1,GALC,PLCD4,TOX2,HMGCR,MBP,MYH3,MYT1,NPTX2,NTRK3,IGSF11,PAX6,PCDHGC3,PLCB2,PLCD1,PCMTD2,HES6,SPP1,PLCB1,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA2,HIF3A,PCDH20,MSRB3" Drug 1226_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-04 1.00E+00 1.50E-03 1.70E-02 39 186 "CDC42BPA,PKP4,GAS7,STX16,ALDH7A1,KIF1A,MPDZ,BID,CFLAR,C5,CBFA2T2,ZMYM4,FOXN3,ABI3BP,CRY2,CTH,GPRASP1,GIT2,EDN1,PRELID3A,OGA,MSL3,GPER1,DIDO1,MMP16,GIT1,ADAM22,NACA,NFYA,OXTR,PTPRH,C1orf54,GAL3ST4,RGS4,HSPA4L,PDZD2,TSNAXIP1,ZBTB43,SEMA3B" Drug 1607_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.09E-04 1.00E+00 1.50E-03 1.70E-02 36 167 "NDRG2,GAS7,ARRB2,DNAH17,CFLAR,ST3GAL5,CD86,CD38,FOXN3,CHN2,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,ZFYVE16,FAM13A,MBNL2,ING4,PACSIN2,PDE4B,PDE4D,GPSM2,SMOX,SGK1,SLA,ARHGEF40,ELMO2,MAPKBP1,ZSWIM8,SPTAN1,SAMSN1,PLCB1,TCF4,TK2,FLRT2" Drug ctd:C558013 NSC 689534 CTD 1.09E-04 1.00E+00 1.50E-03 1.70E-02 225 1570 "ASIC1,RNF157,KLHL13,KIAA1324,WDR35,AK2,SRPX,APBA2,EPB41L5,LGR5,ARNTL,ARRB1,ZSCAN18,ALDH7A1,BACH1,BARD1,SEC11C,BCHE,BID,BLM,CFLAR,PROM1,DST,C5,CACNA1A,PRC1,SCARB1,ARHGEF2,CCPG1,CLGN,NOG,CHN1,ARHGAP22,QKI,AHCTF1,PREPL,CREM,AKAP12,HAPLN1,PHACTR3,FAM169A,SLITRK5,PITPNM3,APPL1,PHF14,PLCXD3,PNPLA8,CTH,FAM131B,ARHGAP32,EARS2,DBI,AIF1L,RUSC2,DDX46,RHOBTB1,RAB39B,NR1D2,CPEB2,SLC12A6,ARRDC4,ECM2,DUSP9,GOLT1B,EDN1,TMTC1,FRY,OPTN,FAM13A,EGFR,KMT5B,EIF5,EIF1,ENO2,SIRPB1,CD320,TBC1D16,TUBA1B,CEP78,GTF2IRD2,FGF1,AMOTL2,SCARA3,SYNCRIP,SEMA4D,FLNC,NOP56,EFCAB2,TRIM16,OGA,FYN,SDCBP2,DENND2A,ERAP1,ACSS1,GLUL,KDM2B,KCNMB4,GNAL,FERMT2,CIT,FICD,GUCY1A1,HAS2,BACH2,HSPA1L,IDH3A,IFI16,SCIN,IL6ST,ZNF678,JAK2,SLC35G1,CREG2,L1CAM,LAMP2,STMN1,NCOA7,LSS,MAP2,AQP11,MATN2,MBD1,MBNL1,CHIC1,MIA2,MT1M,THYN1,MYO5A,HNRNPM,NCF2,NELL2,NME4,CLDN11,PDE1C,ENPP2,SLC10A4,GNG2,NALCN,GPSM2,JAKMIP1,SLC25A23,PCDH18,FA2H,PRKAB2,CEP41,PRPH,STK32A,PTPRB,PTPRD,PTPRH,PTX3,RADX,UBR7,RGS4,RGS12,SLC25A36,MCMBP,RPS6KA2,MAP6D1,PTGR2,CLIP1,MAPK12,CSRNP3,SCN8A,FNIP1,HES6,FOXRED1,SH3BGR,FAM102A,CPEB3,HKDC1,CNKSR2,FAM81A,SEPHS1,SLC8A1,SLC9A5,CPEB4,MYH15,TTC17,LIMCH1,FAM219A,TRERF1,KDM3A,NMNAT2,ARHGAP26,CDK19,ZBTB43,SEPT8,CEP68,SULF2,ARC,SYT1,ASTN2,ANKRD12,MTCL1,DNMBP,KLHL4,TCF4,SYNE1,OBSL1,SLC35G2,GPR161,HEY1,TIMP4,CBX5,TMPO,PDSS1,NEIL2,UBTF,OSBP2,VLDLR,CLDND1,KCNT2,ATP6V0E2,TMEM237,RNF103,TMEM178A,NAV3,PLSCR4,RTN4,HNRNPA3,FAM219B,MSRB3,FRMD6" Drug 2883_UP Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ALK,ATP1A3,CFAP410,HAP1,SCARB1,ARHGAP33,CRY2,TMCC2,DTNB,HSD17B14,ERBB2,DLC1,FYN,SYT17,SOX21,HLF,IRF8,KCNN2,AFDN,ADAM22,NFIX,OGG1,PLTP,CEP41,MAPK7,C1orf54,ZNF493,ZMAT4,TRIM68,RGS12,ZFP2,RASA3,DZIP1,IZUMO4,ARC,TBCEL,TK2,FAM155A,XRCC4,EVI5,KCNAB1" Drug 6816_UP Dacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "FZD9,BEGAIN,AMT,APAF1,APLP1,SEMA4G,ALDH7A1,ADGRB3,CACNA1A,HAP1,ARHGAP33,CBARP,SLIT2,EDNRA,MBNL2,ERCC2,REEP2,FGF13,FYB1,ALDH1L1,GCNT2,ADAM28,RUNDC3A,GNAL,SPACA9,ICA1,ZNF862,NOVA2,CDK18,ENPP2,PFKFB2,PPARA,KLHDC8A,MRAS,SH3GL3,FNDC3A,LIMS2,CCDC88A,CDK19,PARP11,KAT6A" Drug 4595_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "C1QTNF3,ALK,GAS7,BCAS1,BMPR1B,ARHGEF2,LARGE1,B4GALT6,RAB28,CREM,ABCG1,CNTNAP2,ARHGEF4,MFAP3L,EDN1,F5,CORO2B,BAIAP2,TRMO,ZNF44,DISC1,GCNT2,TDRKH,TPPP,MMP16,NEFH,NF1,NOVA2,PDE4A,PFKFB4,PTPRB,ACSS3,CCDC40,KLHDC8A,SOX15,UNC5B,SZT2,PCDHGA10,TNS1,UCHL1,GAN" Drug 7437_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,NCOA1,CFLAR,SRSF11,CSNK1E,GREB1,INTS1,SGSM2,MAMLD1,EGR3,PLEKHA1,EFCAB2,TRAF3IP2,GRB10,ATXN2L,IPO5,MBP,MEIS2,NEK1,PCDH9,KCTD15,PLEC,POLG,PRKAR1B,CEP97,SBF1,GALNT10,SH3BP2,FBXO11,FNDC3A,PEX26,BTBD7,TSPYL2,POGZ,PHLDB1,METTL3,TRIO,VAV1,UPF3A,HPS4,MPPE1" Drug 6444_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADRA1D,CDC42BPA,ARHGDIG,CDK13,CACNA1G,CFAP410,EPS15L1,CABP1,HAPLN1,ARHGEF10,DAPK1,KIAA0319,ST3GAL6,FHL1,DCTN2,GAD1,KIT,MBD1,AFF1,MX1,NF1,CNOT4,PLTP,LRP12,SAMD9,RGS4,KCTD17,SH3BP2,ST8SIA1,PPP4R3A,KANSL3,SNCA,FAIM2,SYNE1,OBSL1,HIF3A,RIMBP2,WIPF1,ZNF711,SLC30A3,EMSY" Drug 7295_DN Homochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "C1QTNF1,CDC42BPA,PPFIA3,BID,C5,CA12,ARHGEF1,ARHGEF2,CHN2,CLCN3,DZIP3,FAM131B,SGSM2,CDON,FAM13A,FGFR1,PRRC2B,GPER1,CNTRL,HNMT,MPP2,NFYA,OGG1,PTN,SH3TC2,RPS6KA2,SBF1,FAM102A,FHOD3,PEX26,BTBD7,SLC22A4,IQCE,OBSL1,TNS2,CBX5,ZKSCAN5,PLPPR2,SH3GLB2,URM1,PCBP4" Drug 3575_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "LTBP4,BIN1,KCNAB2,APC,EPB41L5,ARRB2,SYNJ2,CAMK2A,USP2,GREB1,PARD6A,EDNRA,PIPOX,F5,TRAF3IP2,GAD1,ERAP1,INPP5K,GCNT2,CACFD1,IL6ST,SMAD1,GIT1,ADAM22,NF1,PALM,MINDY2,PPP5C,CNNM2,C1orf54,FNDC3A,FAM214B,SLC9A5,CXXC4,TSNAXIP1,RBM26,TROVE2,SYN2,RPGRIP1L,CHST5,NT5M" Drug 6773_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "RALGAPA1,ADRA1B,ADRB2,SEMA4G,CFLAR,CLGN,EPS15L1,TPP1,CNTN1,RGS6,DCAF4,GSDME,PARD6A,MRNIP,MTSS1L,DLC1,FGFR1,ALDH1L1,SRCAP,GLYR1,IRAK3,IL6R,ITGAM,KCNB1,KCNJ5,MBD1,CLDN11,LRP12,CEP41,TCP11L1,FRMPD1,FAM214B,SNCA,DOK5,SPTB,RGL1,PLCB1,ASTN2,TRIM2,CRTC1,TK2" Drug 4957_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "BIN1,ALDH7A1,SCAPER,CACNA1I,CNTN1,CRMP1,NCOR2,VCAN,DAPK1,TMCC2,DTNB,EGFR,TNK2,ELN,ERCC2,PIPOX,ST3GAL6,GAD1,LPAR4,GSTM5,SOX21,MSR1,NOVA2,RETREG1,PRKAR1B,FAT4,SEMA6D,ZFP2,FAM214B,CCDC88A,SNCA,PHLDB1,PLCB1,SMG6,CRTC1,CHST8,VGF,LAT2,ADAMTS9,HRASLS,DPF3" Drug 7306_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "DOC2A,CDK13,NCOA1,ADAM23,CFLAR,HAP1,ARHGAP33,HOMER3,C2CD2L,HS3ST2,EGFR,ING4,EPB41L2,FYN,ERAP1,ALDH1L1,GRM8,TJAP1,KPNA5,LSS,ADAM11,SETD4,PDE4D,CNNM2,RET,CARF,TRAPPC13,ZNF821,DZIP1,PEX26,IFT122,ZC3H13,ARHGAP26,SPTAN1,SS18,PLCB1,SYT1,ASTN2,PCDHA2,RIMBP2,NT5M" Drug 3531_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "AP2A2,AK2,C1QTNF3,BIN1,PPFIA3,MARK4,CFLAR,SCAPER,SYNGR3,MAGI1,VAX2,MAML1,RUSC2,OPTN,RACK1,ANKFY1,IL6ST,MBD1,MPP2,GIT1,NPTX1,SLC25A36,SH3BP2,ASAP3,FNDC3A,ANKRD6,SLC6A8,SLC22A4,KDM4B,ZHX3,UNC5B,ZBTB43,PHLDB1,STX1A,EXOC7,SLC44A1,CABIN1,ZKSCAN5,HIRA,ZNF74,MAP3K12" Drug 1424_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NDRG2,C1QTNF3,AMT,APBA2,MPDZ,SYNJ2,MTMR3,SLC25A14,RUNX1T1,FOXN3,BAG4,CREM,ENTPD4,ZNF337,SPOCK2,PARD6A,BAIAP2,PRKAG2,ANKFY1,GLYR1,MAN1B1,KCNB1,TAGLN3,NF1,OCRL,PALM,PPP2R2B,CCDC40,RAD51D,TCP11L1,FBXO11,INTS9,ATP10B,STXBP1,SYT1,ANKRD12,MTCL1,TK2,CA14,ZNF74,DPF3" Drug 5843_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ABHD6,ADD2,BIN1,APC,PPFIA3,PDE8B,NCOA1,CFLAR,SLC25A14,NRG2,CSNK1E,SPOCK2,TMCC2,RCAN1,TNK2,DENND4A,FER,BAIAP2,FHL1,FYN,B4GALNT1,DISC1,RNFT2,PLCD1,KBTBD4,BTBD7,ZKSCAN3,COA1,SNCA,DDN,LHPP,TCF4,TRIM2,TNS2,TK2,TRIO,XRCC4,SH3GLB2,MAP3K12,SMIM8,AAAS" Drug 1768_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "EP400,SEMA4G,NRP2,MTMR2,CACNB4,CLTB,MAP4K4,SEC31B,CREM,CST3,EXOG,PCOLCE2,RASGRP2,PRKAG2,IP6K2,TRMO,ALDH1L1,GRIK5,ITGA7,LIG4,MAP4,CNOT4,PDE4B,PDPK1,PNMA3,PPP5C,SATB1,FNDC3A,FAM214B,SLC12A2,ELMO2,COA1,THSD1,EXOC7,CBX5,LAT2,XRCC4,ZNF32,ZNF142,HPS4,FXR1" Drug 6654_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "RALGAPA1,ASIC1,NDRG2,BEGAIN,ANK2,CDC14B,CFLAR,KSR1,BMPR1B,BAIAP3,KALRN,HIP1R,NCOR2,PDE4DIP,CNTNAP2,BRINP1,ARMCX2,HS3ST2,DTNB,EDN3,ANKMY1,EZH1,OLFM1,OGA,SRCAP,TDRKH,ADAM22,OPRL1,PDE4B,ENPP2,RETREG1,PRPH,DCHS2,RASA3,HKDC1,SNCA,SPP1,CAMTA2,ICAM5,KCNAB1,JPH3" Drug 5783_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SYN3,NDRG2,FAM135A,MARK4,BMP7,ST3GAL5,LDLRAD4,USP2,EDIL3,EDN1,EDN3,COQ7,HPCAL4,NEU3,ADAM28,POLL,PRUNE2,SPACA9,SHISAL1,KCNF1,KCNH2,KCNN2,LAMA2,LMO2,MBP,TM6SF1,MEF2C,AFF1,ADAM22,TAGLN3,MAPK3,PTN,PTPRD,GAL3ST4,STUM,SLC11A1,HECW1,SPTB,TPM1,CDK20,PDIA2" Drug 4774_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SYN3,AK2,SEMA7A,APBA2,MARK4,MPDZ,RGS9,CFLAR,CACNA1I,SEPT7,CLGN,NCOR2,VCAN,PUM1,SPOCK2,EIF4G2,HSD17B14,ERCC2,ACSL4,ZNF44,ALDH1L1,PCLO,GRM8,ICA1,C2orf72,KCNN2,KIT,MID1,MMP16,PDE4A,LRRN3,FRMPD1,SLA,ZC3H13,WSCD1,RPGRIP1L,CRTC1,CABIN1,UCHL1,CLDND1,ST7" Drug 5544_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADRA1D,ANK2,CDC14B,CDK10,DNAH17,ATP6V0A1,HIP1R,CD86,SIPA1L1,VCAN,CNTNAP2,DZIP3,SEC14L5,SPOCK2,SLC12A6,FCF1,C3orf18,SPEG,F5,GPD1,RASSF8,MBD1,MSR1,NF1,ABCB1,PPARA,ELOVL2,MARCH1,KHDRBS2,ZDHHC14,TCP11L1,SH3GL3,SYBU,KIF13A,SYN2,TBL1X,WSCD1,ZKSCAN5,VIPR2,XRCC4,TRIM9" Drug 4687_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,AMT,RGS20,MARK4,NUMB,KIF1A,GYG2,SPAG9,SYNGR3,B4GALT6,AKAP7,ARHGEF4,DCAF8,DAPK3,PARD6A,MBNL2,AASS,STX2,ACSL4,FER,SEMA4D,CNTRL,RASSF8,ATXN2L,JAK2,MAP4,MAPT,MAPK7,TMEM260,RIPOR1,SH3BP2,PEX26,KIF13A,SS18,SMG6,TRIM2,TRIO,VIPR2,XRCC4,DNALI1,RNF170" Drug 7384_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "LTBP4,APBB2,APC,PPFIA3,ADGRB2,BAIAP3,HAP1,TAOK2,NRG2,NCOR2,USP6NL,DBT,RUSC2,EXOG,DPH1,EDIL3,IRAK4,COQ7,ETV1,ZMYND10,FGF1,FGFR1,DENND2A,GRM2,MAPT,TAGLN3,PLCD1,PRODH,CNNM2,PTCH1,PTPRN2,TMEM231,RGS4,KIRREL1,TRAPPC13,MAPK12,CSRNP3,ST6GAL1,BTBD7,ZKSCAN3,TRIO" Drug 6312_DN Methiothepin maleate [19728-88-2]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "C1QTNF1,BIN1,AMT,CDC42BPA,APOC1,ALDH7A1,RAB29,NFS1,CNTNAP2,PLPPR4,SLC12A6,FER,EVL,TPK1,OGA,DISC1,INPP5K,TXNL4A,GNG4,GPR37,FA2H,MINDY2,MAPK7,PRPH,CCDC25,SAFB,ASAP3,FUZ,ANKRD6,SMARCA4,NMNAT2,ARHGAP26,CDK19,ELOVL4,KANK1,ZNF34,TNS1,XRCC4,UPF3A,URM1,TIGD6" Drug 5875_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADRB2,MTUS1,AMT,APBB2,MARK4,IQCK,ARMC8,NRG2,VCAN,CNTNAP2,HDAC9,DAPK3,FBXL5,C2CD2L,EIF5,ERCC2,ZNF589,FGF13,INPP5K,AHDC1,MAP4K5,MUM1,L1CAM,MAN2A2,MAPT,MBD1,SCAMP5,TAGLN3,LRP12,POLG,SH3TC2,SH3BGR,ST6GAL1,EPN2,ERC1,ZBTB43,NXT2,XRCC4,VPS35L,NAV3,KAT6A" Drug 1021_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,APAF1,MARCH3,CAMK2G,KYAT1,SOCS6,FAM189A2,LRIG1,PDE4DIP,ARHGEF4,MAML1,DTNA,TSPAN5,EGR3,OLFM1,TMEM164,EFCAB2,B4GALNT1,COPS8,BTN2A1,HNMT,JAK2,MPP2,PCBP3,SETD4,CNNM2,RET,RGS3,TRAPPC13,SGK1,SYBU,KIF13A,KDM4B,IQSEC2,TSPYL2,THSD1,ST5,TTBK2,CHST8,ZNF34,SLC30A3" Drug 370_DN troglitazone; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "CDC42BPA,APBB2,BCL7A,GYG2,PICK1,SEC14L5,KIAA0586,GIT2,PARD6A,DTNA,KCNMB4,RNFT2,IPO5,NF1,NNAT,NPR2,PALM,PDE1C,ABCB1,POLG,PRKAR1B,MAPK10,PRPH,MASP1,SPDL1,RGS3,KCNIP1,DGLUCY,STUM,SH3GL3,KBTBD4,HECW1,UHRF1BP1L,CAMTA2,NXT2,ANKRD12,OBSL1,BHLHB9,HSPBP1,VSNL1,XRCC4" Drug 4399_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "KIAA1324,C1QTNF1,CDC14B,ADAM23,BAIAP3,CFAP410,RHBDL1,CLDN10,TPP1,RCHY1,CNTNAP2,DGKG,DAPK1,DBT,DTNB,HIPK3,EIF4G2,RASGRP2,IGSF6,FGFR1,GRIK5,GRM2,AFDN,NF1,NNAT,OGG1,OPRL1,PDE1C,GPR85,CEP41,RASGRF1,RFX2,RPS6KA2,SH3GL3,KANSL3,OGDHL,SMARCD3,IZUMO4,SYT5,ICAM5,TNS1" Drug 4191_DN Conessine [546-06-5]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,AP2A2,LGR5,ARHGDIG,KALRN,ARHGEF1,ARHGAP22,LHX2,RAB28,LY86,ENTPD4,SLITRK5,TBC1D5,MFAP3L,MBNL2,ZNF391,ETV1,VPS26C,F5,FGFR1,MSL3,SHISAL1,JAK2,KCNF1,PDE4D,RETREG1,ELOVL2,RGS4,MRAS,KANSL3,SLC11A1,SEPT8,SLC44A1,THRA,TIMP4,RUNDC3B,VGF,LMF1,REEP1,KCNAB1,PLSCR4" Drug 6004_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,ALCAM,TRMT9B,APBB2,ARRB1,ALDH7A1,ADAM23,MTMR2,CBFA2T2,ARHGAP33,QKI,HOMER3,AKAP7,CNTNAP2,PPP6R2,DAPK3,OPTN,ACSL4,FECH,HNMT,IL6R,IL6ST,IPO5,MAP4,MAPT,MEIS1,CNOT4,OGG1,LRP12,PRODH,RGS3,SAFB,MRAS,SMARCC2,ZHX3,CEP68,TTBK2,MTCL1,ZKSCAN5,PLPPR2,ZFP37" Drug 2858_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "AP2A2,SEMA6A,SRPX,KCNAB2,GYG2,CLGN,SOCS6,TAOK2,CLCN3,QKI,TBC1D5,GIT2,HIPK3,ANKMY1,KAT8,ZNF589,FGFR1,FHL1,EFCAB2,SYT17,SRCAP,POLL,GPER1,MIA2,PLEC,MINDY2,PRKAR1B,ZNF821,ZFP30,SYBU,BTBD7,ZSWIM8,ARHGEF9,ASTN2,TACC1,EXOC7,TNS2,CRTC1,SLC44A1,TK2,WIPF1" Drug 6818_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SRPX,GAS7,BAIAP3,CFAP410,CACNA1A,USP2,CBFA2T2,CNTFR,NRG2,PDE4DIP,RIPOR2,ELMO1,RUSC2,MBNL2,RAB30,RASSF8,HLF,ITPKB,KCNJ5,MAN2A2,AFF1,ADAM22,ZNF862,NFIX,PRKCB,ZDHHC14,TRIM68,EMID1,ZNF821,SH3BP2,ASAP3,FAM214B,SLC14A1,SNCA,CRTC1,CDK20,KCNK12,NT5M,DNALI1,ITM2C,JPH3" Drug 2224_DN Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NDRG3,NDRG2,C1QTNF3,AMPD3,APBA2,PLA2G4C,NCOA1,ST3GAL5,ARHGEF1,ARHGAP33,TPP1,FAM189A2,CREM,CSF1R,DAPK3,MFAP3L,ZNF589,SEPT9,GLYR1,GNG4,TDRKH,GRIK5,MIA2,MPP2,MSI1,MYO7A,ZSCAN2,RNASEL,FNDC3A,SYBU,PEX26,SOX3,KDM4C,PLCB1,ARC,MTCL1,MCF2L,TRIM2,SPHK2,MAP3K12,SEMA3B" Drug 3821_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APAF1,BMPR1B,HAP1,CD86,DLGAP2,TPP1,FAM189A2,AKAP6,CRMP1,EDIL3,LRRC17,IGSF6,ST3GAL6,FGFR3,HPCAL4,NEU3,RAB30,GRM8,GSTM5,ATXN2L,KCNB1,MAN2A2,MEF2C,ZNF862,P2RY13,NF1,NPTX1,PFKFB4,POU6F1,LRRN3,CEP41,ELOVL2,ZMAT4,RET,RGS12,RNASE1,RNASEL,KLHDC8A,IZUMO4,ICAM5,FLRT2" Drug 2959_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "AMT,MARK4,SLC4A4,ADAM23,SYNJ2,CLGN,RCBTB2,PDE4DIP,SLITRK5,DTNA,EGR3,EIF4G2,ERCC2,FGFR1,ATP2C1,SEPT9,INPP5K,MSL3,SLC2A6,ITGA7,ITGAM,KPNA5,LSS,MAP4,SCAMP5,MX1,MYO9A,PDE4A,ENPP2,PLEC,PTPRO,PEX26,FAM214B,ARFGAP1,TSPYL2,DDN,R3HDM1,KAT6B,CABIN1,TPM1,ATP6V0E2" Drug 5095_DN Thiocolchicoside [602-41-5]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "MTUS1,KCNAB2,APBB2,ZBTB10,SLC4A4,ALDH7A1,KRIT1,LARGE1,SRSF11,SOCS6,RAB28,STOML1,HOMER3,BAG4,CREM,CSNK1E,DYNC1I1,DENND4A,BAIAP2,SMC2,CSPG5,AGFG1,JAK2,KCNN1,KIF2A,SLC11A2,PIK3R1,PTCH1,PID1,KIRREL1,AMBRA1,SLC14A1,SNCA,SPATA7,PHLDB1,BHLHB9,TRIO,HIRA,LMF1,EVI5,AAAS" Drug 5683_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,ALCAM,APOC1,CLGN,HOMER3,FAM169A,DCAF8,GIT2,MFAP3L,MED12,CDKL3,ZNF589,ERAP1,TXNL4A,POLL,GPD2,HNMT,MAP4,SCAMP5,MITF,SLC25A23,PLXNB1,PRPH,PTCH1,TMEM231,MAPK12,FERMT1,EPN2,FAM214B,LIMCH1,ERC1,ELOVL4,SEPT8,EXOC7,AP4E1,BEX4,PARD3,TPM1,GDPD5,MPPE1,SMIM8" Drug 3180_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "AMPD3,APAF1,THSD7A,HIP1R,MYRIP,SLITRK5,PHF14,DBT,DTNA,HIPK3,SEMA3D,ERBB2,FGF12,HPCAL4,HPGDS,PRDM5,GRM8,HNMT,KITLG,TAGLN3,MX1,PCBP3,PDE4A,PDE4D,GPR85,PTPRN2,RASGRF1,DOK5,SSTR2,PLCB1,KIAA1107,HIF3A,AP4E1,TIMP4,TK2,TRIO,TRO,VGF,XRCC4,TRIM9,AP3B2" Drug 7436_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NDRG3,APOC1,PPFIA3,NCOA1,SYNJ2,PLEKHB1,B4GALT6,STOML1,TMEM184B,LRIG1,KIAA0586,SUGP2,IRAK4,STX2,CGREF1,FYN,SRCAP,GRB10,MIA2,SLC25A23,PLXNB1,RETREG2,PPP3CC,PRODH,ZCWPW1,FBXW7,FBXO11,ABLIM3,ZKSCAN3,ZHX3,ZBTB43,TROVE2,PHLDB1,MTCL1,KAT6B,CABIN1,TRIO,ZNF45,ZNF184,SMIM8,GAN" Drug 591_DN "N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Down 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "BIN1,OGT,ARNTL,CDK13,RASL11B,RUNX1T1,ARHGAP33,FOXN3,FAM189A2,CDC42BPB,NCOR1,NR1D2,DNAJB6,MRNIP,ZMYND10,ZNF589,HPCAL4,NEU3,PTPRT,IGF1,TJAP1,MBD1,OXTR,PFKFB2,SUSD4,RASGRF1,RNASE1,ZFHX4,SEMA6D,SH3BP2,SH3GL3,FUZ,SLA,SLC11A1,KDM4B,DOK5,PHLDB1,DNMBP,TNS2,TRIO,SLC17A7" Drug 2391_DN Nortriptyline hydrochloride [894-71-3]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NDRG3,ALK,DOC2A,SLC4A4,N4BP2L1,CFAP410,CAPN3,CAST,CD86,ARHGAP33,IQCK,RCHY1,ARHGEF4,ZNF337,DTNA,TSPAN5,EIF4G1,F5,ZNF589,SEMA4D,CINP,ZNF44,TRAF3IP2,USP19,ZNF276,SPACA9,ELOVL5,JAK2,MAP4,PFKFB2,NLE1,GTDC1,SBF1,STUM,ANKRD6,ZBTB43,EXOC7,PLPPR2,VIPR2,NPDC1,URM1" Drug 920_DN 5-aza-2′-deoxycytidine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,ABHD6,NDRG2,AP2A2,BIN1,ST3GAL5,SPAG9,SCARB1,TAOK2,LHX2,QKI,GIT2,SLC12A6,DTNA,VPS13B,ANKMY1,TAOK3,DLC1,FHL1,SYT17,POLL,CLASRP,CCSER2,POLG,MINDY2,SAMD9,TMEM104,ASAP3,FUZ,BTBD7,ZHX3,ERC1,DIP2A,TACC1,FRYL,TMEM121,ZNF34,CABIN1,VGF,LMF1,ZNF74" Drug 4119_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NME5,AK2,BIN1,AMT,APLP1,APOC1,ARRB2,GYG2,B4GALT6,QKI,CRMP1,SIPA1L1,RUSC2,TOM1,EGFR,ING4,EZH1,FGFR1,FAM49B,DISC1,SRCAP,PRRC2B,GRB10,GRM8,KCNF1,ADAM22,SERPINI1,LRP12,PPP2R2B,TMEM104,RPS6KA2,BTBD7,LIMCH1,SNCA,ZHX3,ZBTB43,TROVE2,EXOC7,PARD3,CDK20,KCNAB1" Drug 6490_DN Iodipamide [606-17-7]; Down 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SRPX,BCAS1,CFLAR,MTMR2,SLC25A14,B4GALT6,AKAP12,SIPA1L1,FAM169A,DZIP3,GIT2,JAKMIP2,KCTD3,MALT1,COPS8,GPR37,DIDO1,ELOVL5,MAP4,NFYA,FSD1,CNNM2,TMEM104,NKAIN1,SUPT20H,HSPA4L,SGK1,FUZ,ELMO2,ZC3H13,SPART,TK2,BEX4,FAM155A,CLDND1,XRCC4,ZFAND5,HPS4,MPPE1,FZD3,RNF170" Drug 2717_DN Ebselen [60940-34-3]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "BRAP,AMPD3,APBB2,APC,PPP4R4,ARRB1,FUBP1,CAPN3,CLCN3,HOMER3,NRG2,USP6NL,E2F5,SUGP2,ERCC2,ST3GAL6,KHDRBS3,CELF1,SEPT9,ALDH1L1,GPR75,RAB40B,GNG4,PADI2,MAP4,NNAT,CNTLN,SBF1,GALNT10,ANKRD6,ELMO2,MYH15,KDM4B,RBM26,ZC4H2,OBSL1,TK2,SH3GLB2,EVI5,UBE3B,NLRP3" Drug 6936_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ARNTL,STX16,BCL7A,HIP1R,LRRFIP1,HOMER3,ABCG1,FBXL5,PHF20L1,IRAK4,CGREF1,MPP6,INPP5K,GRM8,HNMT,HSF2,KCNF1,KHK,KIF2A,IPO5,MAP4,LYRM9,NF1,SETD4,OCRL,PPP3CC,PRODH,TMEM231,SH3BP2,SYBU,ZKSCAN3,CDK5RAP2,SIN3B,TRIM2,TNS2,VGF,LMF1,NDRG4,MAP3K12,EPM2A,RNF146" Drug 7518_DN DNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "MTUS1,APAF1,PPP4R4,MARCH3,CFLAR,SYNGR3,ARHGEF2,MAGI1,ASIC3,RAB26,CNTFR,PDE4DIP,CNTNAP2,SLITRK5,SPOCK2,EXOG,DUSP9,TUBD1,BAIAP2,ANKFY1,TRMO,DISC1,GLYR1,CACFD1,KHK,MIA2,MX1,NPR2,PLXNB1,POLG,BTBD7,DDN,PLCB1,ASTN2,IQCE,TNS2,TNS1,ZKSCAN5,LAT2,XRCC4,RNF170" Drug 1987_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,NDRG3,BRAP,PKP4,SHROOM2,CDC14B,ARNTL,CFLAR,BMP7,MTMR2,HIP1R,KRIT1,FAM189A2,QKI,ZNF337,ZNF804A,C2CD2L,RCAN1,FCGRT,GAA,GALC,ARFIP1,GRB10,IFI16,KIF5A,KIFC3,MX1,NEK1,NFYA,NTRK2,NTRK3,OGG1,ENPP2,PLCD1,ZNF821,FAM102A,AMBRA1,SNAP25,NSFL1C,NPL,EVI5" Drug 5096_DN Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "MTUS1,BIN1,APBB2,APOC1,KRIT1,ARHGEF2,TAOK2,STOML1,CREM,CNTNAP2,EDIL3,HIPK3,CNNM1,MBNL2,RGS17,STX2,DENND4A,SCML2,FGFR1,GLYR1,POLL,SHISAL1,IL6ST,JAK2,KCNN1,MX1,PDE4A,BCAS3,PID1,RGS3,TCP11L1,SCN8A,ZFP30,LIMCH1,ELOVL4,ZNF34,CABIN1,ZNF24,ZNF225,UBE3B,SENP7" Drug 2732_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ALK,BEGAIN,PPFIA3,DNAH17,ADGRB1,BMP7,SGCE,SCARB1,CDO1,CHN2,TAOK2,PICK1,PCYT1B,EDNRA,PLXNC1,VPS13B,F5,KAT8,DOT1L,INPP5K,GRM2,NXPH3,FAM69A,KHK,CNOT4,PDE4D,PGAM2,PPP5C,CEP41,CNNM2,PTPRN2,RGS12,SP4,IZUMO4,PHLDB1,SYNE2,VGF,LMF1,VSNL1,ZFP37,SLC17A7" Drug 6775_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "RALGAPA1,KIAA1324,BIN1,KCNAB2,PRX,PDE8B,N4BP2L1,SCAPER,CBFA2T2,ARHGEF2,CLGN,QKI,SIPA1L1,GREB1,DOCK4,CDON,HIPK3,MBNL2,STX2,RRAGB,ZNF589,FUT9,SPACA9,GRIK5,IL6R,JAK2,KIT,MN1,ZNF862,PDE1C,NLE1,PPARA,RAD51D,TCP11L1,BTBD7,COA1,KIF13A,SPTAN1,ZEB1,TMPO,PLPPR2" Drug 1009_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NME5,AK2,C1QTNF3,SYT13,SEMA4G,ARRB1,SCARB1,ARHGAP33,SLC4A8,RCHY1,PDE4DIP,VPS13B,ZNF589,SRCAP,GRB10,SLC2A6,JAK2,KIF5A,MAN2A2,MSR1,LYRM9,ZNF862,CDK18,SLC25A23,WDR25,RAD51D,CARF,PNMA8A,TCP11L1,RXRA,ZNF821,SH3BP2,FAM214B,SLC6A8,ZHX3,TSPYL2,TROVE2,JMJD6,BHLHB9,CABIN1,PARP11" Drug 6401_DN F0447-0125; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADCY6,AMT,SEMA7A,PKP4,PRX,ATP6V0A1,PROM1,USP2,RAB26,ABI3BP,NRG2,CSF1,MYEF2,EDNRA,SEMA3D,ETV1,FGFR1,FLT1,CGREF1,FYB1,DENND2A,CSDC2,RUNDC3A,RAB30,GRIK5,HAS2,MATN3,AFDN,MMP16,MN1,NPR2,TCP11L1,ASAP3,SP4,NFASC,PHLDB1,CRTC1,TK2,TNS1,VGF,ZFP37" Drug 3421_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NME5,LTBP4,DOC2A,PPFIA3,PDE8B,ST3GAL5,CAMK2G,HIP1R,SCARB1,TAOK2,LHX2,TPP1,HOMER3,AKAP7,ABI3BP,NECTIN3,CSF1,GREB1,MAML1,RUSC2,EDNRA,DLC1,ZNF589,FGF12,FGFR1,DISC1,LSS,MBD1,MID1,MSR1,SLC25A23,PTPRE,GAL3ST4,RGS3,SYBU,CLSTN2,THRA,TIAM1,CDK20,VGF,REEP1" Drug 7090_DN SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADD1,SRPX,BCAS1,KIF1A,BCL7A,SCARB1,LHX2,FAM189A2,PARD6A,RCAN1,DTNA,ING4,PDLIM5,ZNF276,TXNL4A,POLL,CACFD1,KHK,MAP4,MBD1,ADAM22,NCAM2,SETD4,PPP2R2B,RGS12,NEK11,TCP11L1,FERMT1,PEX26,EPN2,SMARCC2,SOX3,LHPP,TROVE2,ASTN2,PDLIM2,TBL1X,TP53BP2,PLPPR2,SEMA3B,URM1" Drug 5458_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADD2,ADORA1,BIN1,AMT,OGT,APC,GAS7,PPP4R4,ALDH7A1,RGS11,CFLAR,CACNA1I,CACNA2D2,ARHGAP24,SPOCK3,DMPK,C3orf18,CORO2B,PRELID3A,ALDH1L1,RUNDC3A,GRB10,KHK,MYO7A,PCDHGC3,DUSP26,LRRN3,PRKAR1B,GRAMD1C,VPS13C,PTCH1,PTX3,ZMAT4,SLC11A1,ATP10B,CLSTN2,TNS2,PCDHA5,UCHL1,DNALI1,KCNAB1" Drug 6632_DN SR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "RALGAPA1,BIN1,CDC42BPA,APBB2,ST3GAL5,MYRF,SOCS6,CREM,SH2B1,ABCG1,ARHGEF4,ARMCX2,MFAP3L,FBXL5,TNK2,MRNIP,COQ7,DENND2A,GAD1,GLYR1,POLL,TDRKH,HLF,ADAM22,PDE1C,PPARA,WDR25,SH3TC2,ZNF821,MYH15,IQSEC2,ZBTB43,CAMTA2,SUPT5H,SMG6,TCF4,SZT2,TNS1,RPRM,LMF1,MAP3K12" Drug 4166_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APBA2,KCNAB2,APOC1,MARK4,AZGP1,GYG2,RUNX1T1,CDH2,TAOK2,STOML1,WHRN,DAPK1,KLHL3,DMPK,EDN1,EGR3,EIF4G2,SCARA3,FYB1,ZNF44,ALDH1L1,GDF9,GPER1,IL6R,NOVA1,NTRK2,GPR85,ELOVL2,RGS12,PKNOX2,FAIM2,KDM4B,SPART,DMXL2,PCDHGB6,DOCK9,SLC35G2,DNAH7,TNS1,SLC30A3,SLC17A7" Drug 7289_DN Phenindione [83-12-5]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "BIN1,APBB2,FAM131A,EIF4G3,RAB29,WASF1,PTBP2,RCBTB2,SRSF11,RAB28,AKAP7,WHRN,NRG2,DBT,FBXL5,COPS8,SLC2A6,MAP4,MKLN1,NFYA,PDE1C,PDPK1,PLCD1,RAD51D,GTDC1,RPS6KA2,CLIP1,FAM214B,LIMCH1,TMCC1,PEG10,ARHGAP26,ZBTB43,CEP68,TTBK2,DIP2A,MGRN1,HIRA,UBTF,LMF1,XRCC4" Drug 5773_DN Methacholine chloride [62-51-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "MTUS1,AMT,APLP1,PPFIA3,CDC14B,SEMA4G,MARCH3,SYNJ2,ARHGEF2,CREM,ARHGAP24,C2CD2L,ING4,CDKL3,FGFR1,CINP,HTATSF1,SHISAL1,NF1,NFIX,NLE1,PPP5C,PRPH,ZNF821,ASAP3,LIMS2,ZKSCAN3,SMARCA4,SMARCD3,TMCC1,KDM4C,PHLDB1,ARHGEF9,COBL,TMEM121,CABIN1,METTL3,PLPPR2,WIPF1,WNT7A,MAP3K12" Drug 142_UP tolbutamide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ALCAM,BCL7A,NRP2,BMP7,SLC25A14,HIP1R,CBR1,SYNGR3,AP4M1,ZMYM4,ZBTB24,LYPD1,DMPK,MED12,DTNA,MBNL2,TAOK3,AFF2,SARAF,ATXN2L,JAK2,LIMS1,PAXBP1,MBD1,PTOV1,PLEC,RETREG2,PRKAR1B,SUSD4,ZDHHC4,RGS12,NEK11,GALNT10,MYCBP2,SEPT8,TBL1X,ATMIN,TP53BP1,UBE3A,ZNF142,GDPD5" Drug 1463_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NME5,LTBP4,ALK,CDC42BPA,KCNAB2,CDK13,SLC4A4,ADGRB3,ARHGAP33,EDIL3,STX2,DCTN2,ERAP1,GLYR1,POLL,CNTRL,CACFD1,HLF,KCNH2,KCNQ3,MBD1,KITLG,NFYA,RETREG1,RELN,EMID1,SH3BP2,SLC2A5,PPP4R3A,MAPKBP1,SNCA,SPTAN1,PHLDB1,ARC,CRTC1,CABIN1,CHST5,TUBB1,SLC30A3,MPPE1,SENP7" Drug 61_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ACTN1,CAPN3,HIP1R,SCARB1,CHGB,TMEM184B,C2CD2,HINFP,JAKMIP2,TSPAN5,OPTN,PLEKHA1,ETV1,FGF1,PRKAG2,PCYOX1,TRAF3IP2,B4GALNT1,GFER,BTN2A1,SOX21,SLC2A6,MYO7A,NFYA,NTRK3,NUCB2,FSD1,PRKAB2,PRODH,RIPOR1,CCDC40,C1orf54,RNASE1,SLA,ELMO2,SMARCC2,NMNAT2,MYCBP2,TAL1,WIPF1,UBE3B" Drug 996_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,ADCY6,SRPX,PKP4,EPB41L5,PPFIA3,MADD,CDK13,CA12,KYAT1,SLC4A8,PDE4DIP,MFAP3L,LYPD1,DMPK,HIPK3,KAT8,ZNF589,B4GALNT1,ERAP1,GLYR1,GPD2,ATXN2L,ELOVL5,KPNA5,MITF,NEK1,NF1,SLC25A23,PPP2R2B,FAM184A,SH3BGR,SH3BP2,ANKRD6,BTBD7,SLC22A4,DIP2A,FBXW11,RPGRIP1L,VGF,EPM2A" Drug 5749_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,NDRG2,SEMA7A,SLC4A4,EIF4G3,SCAPER,GYG2,CACNA1I,LDLRAD4,AKAP5,CREM,CSF1,HIPK3,ING4,ZNF549,FGF1,GABRG2,SEPT9,PADI2,HNMT,KHK,KIT,LSS,MEF2C,AFF1,MN1,MYO7A,NF1,PALM,LRRN3,ZCWPW1,RGS12,ZNF821,SLC11A1,ATP10B,PHF24,CRTC1,HIF3A,CHST5,RPRM,SPHK2" Drug 2518_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADD2,BBOX1,DOC2A,APAF1,APBB2,APOC1,PLA2G4C,AZGP1,LDLRAD4,HAPLN1,PDE4DIP,DZIP3,USP6NL,SV2B,HS3ST2,E2F5,SEZ6L2,EDN3,DLC1,AFF2,GATM,PRUNE2,STMN2,ICA1,KCNQ3,KIF5A,MSI1,PCDH9,PCSK5,CCSER2,FSD1,KCNIP1,RASA3,SH3BP2,PPM1E,FERMT1,PDZD2,SPTAN1,MCF2L,SSBP2,TUBB1" Drug 3532_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SEMA6A,ALCAM,ABCD2,APBA2,FAM131A,ATP2A2,ADAM23,SULT4A1,LY86,CRMP1,CSF1R,RASSF2,GIT2,DMPK,FRY,TNK2,ERCC2,GALC,DISC1,SEPT9,ELOVL5,TJAP1,ITGA7,MMP16,TAGLN3,NF1,NTRK3,PDE4D,PTN,ZNF493,RFX3,TCP11L1,RPS6KA2,SYBU,TROVE2,RPGRIP1L,SYNE1,DOCK9,PDIA2,ITM2C,ST7" Drug 7450_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,ABHD6,BIN1,SEMA4G,CDK13,CFAP410,CACNA1A,CLGN,FOXN3,CNTFR,SLC4A8,SIPA1L1,SEC14L5,TMCC2,EGFR,FGFR1,OGA,MALT1,PRUNE2,TDRKH,KCNN1,MAP4,MMP16,ADAM22,MYO7A,NOVA2,NTRK2,PAX6,PCDHGC3,PDE4B,RIPOR1,CLIP1,SLC11A1,PLCB1,TNS2,TIAM1,PIK3R5,CDK20,PLPPR2,TFIP11,SLC17A7" Drug 6136_UP Trifluridine [70-00-8]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APBB2,EPB41L5,APOC1,ARHGDIG,ATP2B2,NRP2,CACNA1G,LDLRAD4,LARGE1,SLIT2,CNTFR,CREM,ABCG1,BRINP1,EGR3,PLEKHA1,FGF1,FHL1,KHDRBS3,NSG1,ICA1,KHK,MBNL1,MSI1,NF1,NRCAM,DUSP26,PLTP,SEPT4,PPP5C,WDR25,RGS12,CARF,SH3GL3,FRMPD1,TMCC1,PHLDB1,DMXL2,TRIM2,AMACR,PRDM10" Drug 7487_DN semustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SEMA6A,ALCAM,PLA2G4C,SLC4A4,ADGRB1,SYNJ2,CA4,CAMK2B,CACNA2D2,VAX2,QKI,AKAP7,BAG4,CSF1,EIF5,STX2,CNTRL,SYNPO,ITPKB,JAK2,KIT,LIG4,AFF1,PLCD1,GSTCD,RPS6KA2,ASAP3,SOX15,PHLDB1,PLCB1,ARC,TACC1,WSCD1,PCDHA5,TMEM121,TMPO,BEX4,TUBB1,SPHK2,EVI5,AP3B2" Drug 7297_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "CFLAR,NRXN3,AKAP5,VCAN,CYBB,SPOCK2,DTNA,EDN1,FRY,CELSR3,PRELID3A,CSPG5,GAD1,DISC1,ZNF276,SPACA9,PTPRT,BACH2,HLF,IL6ST,FAM69A,KPNA5,SCAMP5,NOVA2,SERPINI1,MAPK3,FAT4,KCTD17,SCN8A,SH3BP2,LIMCH1,TMCC1,SPP1,SS18,EXOC7,AP4E1,SLC44A1,TK2,LAT2,XRCC4,SEMA3B" Drug 264_DN MK-886; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASIC1,NDRG2,LTBP4,CDK10,ARRB2,CAMK2A,CDH2,ARHGAP33,DLGAP1,B4GALT6,CREM,CRHBP,OSBPL3,SIPA1L1,DAPK1,GIT2,FEM1B,SPEG,CDKL3,PRRC2B,LILRA2,AP4S1,STMN1,MBD1,C19orf57,HYDIN,CNNM2,MTMR10,ZCWPW1,TRIM68,KLHDC8A,TCP11L1,FERMT1,ST6GAL1,KBTBD4,HECW1,KDM4C,PHLDB1,CRTC1,CDH22,RIMBP2" Drug 3360_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ADRA1D,ALK,AMPD3,SEMA7A,CDC14B,ARRB1,DNAH17,CBFA2T2,SLIT2,SULT4A1,HOMER3,CNTN1,WHRN,PHF14,CTH,SPOCK2,DMPK,HIPK3,FGFR1,TMEM8B,SEPT9,GCNT2,SRCAP,KCNJ5,KCNN2,SMAD1,MMP16,GPR85,PURG,FSD1,PRKAR1B,MAPK7,PREX2,SAMSN1,ARC,PCDHGA10,TNS1,KLC2,XRCC4,KCNAB1,JPH3" Drug 3389_UP Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "FZD9,ADORA1,ADORA2A,AP2A2,NME5,ALCAM,KCNAB2,SLC4A4,LDLRAD4,CAMK2B,VAX2,SULT4A1,AATK,ARHGEF10,VCAN,USP6NL,TMCC2,HSD17B14,ERCC2,PIPOX,RASL10A,GPR75,NXPH3,ITGA7,KCNN1,KIFC3,MX1,NPTX2,LRP12,PPP5C,CEP41,SNRK,PTPRH,ENOX1,ST6GAL1,CXXC4,SP4,HECW1,LMO3,CRTC1,VLDLR" Drug 6888_DN carmustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SRPX,LTBP4,APC,PPP4R4,MPDZ,BMP7,CA12,CAMK2G,MAGI1,VAX2,SULT4A1,ABCG1,SIPA1L1,PDE4DIP,FAM169A,DZIP3,MFAP3L,PRKAG2,DISC1,GPR37,HSF2,TJAP1,INPP5B,MAN2A2,LYRM9,CNOT4,RPS6KA2,KIF16B,ASAP3,ANKRD6,CXXC4,PDZRN3,CDK19,CEP68,VPS13A,KIAA0930,HEY1,RPRM,ZNF24,GDPD5,HPS4" Drug 5997_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ASPHD1,ADGRF5,CDC42BPA,GAS7,ARHGDIG,SCAPER,RCBTB2,TAOK2,CRMP1,PDE4DIP,EBI3,EGFR,C3orf18,VPS13B,RASGRP2,FHL1,SCARA3,CAMKK2,DISC1,RUNDC3A,PCLO,GSN,ATXN2L,KCNJ5,MAP4,VPS13C,KLHL11,PKNOX2,SNAP25,SSTR2,RGL1,SYP,SYT5,PCDHGA10,TNS1,UGT8,LAT2,CLDND1,DNALI1,ITM2C,HRASLS" Drug 2994_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "ABHD6,FZD9,AMPD3,ALDH7A1,MYOM1,BMP7,CACNA2D1,HIP1R,AKAP6,NRG2,NCOR2,CNTNAP2,PITPNM3,EXOG,EDN3,CNNM1,SRPK3,STX2,FGFR1,DCTN2,FYB1,GPR75,SCIN,PACRG,MYH3,NELL2,BCAS3,RASGRF1,GAL3ST4,RFX2,SH3BGR,ASAP3,CNKSR2,SLC11A1,LHPP,PHF24,PCDHA5,TIAM1,UGT8,PRDM10,FZD3" Drug 4564_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "NME5,SYNGR3,TAOK2,PLAA,QKI,CTH,ARHGEF4,ARHGAP32,DBT,KLHL3,EDNRA,RGS17,ERCC2,EZH1,CINP,CGREF1,OGA,FYN,DISC1,POLL,TDRKH,JAK2,KHK,L1CAM,PDE1C,STRN3,CNNM2,SAMD9,PID1,FAM184A,SUGCT,SH3GL3,ASAP3,CCDC88A,SMARCC2,TMCC1,TK2,TMPO,LMF1,XRCC4,ZNF711" Drug 3239_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APAF1,APC,ATP2B2,SYNJ2,LDLRAD4,CA8,TPP1,FAM189A2,ABI3BP,SIPA1L1,CYBB,HIPK3,F5,FAM198B,DLC1,FGFR1,SCARA3,GPER1,GSN,KCNJ5,MAN2A2,NELL2,MAPK10,SNRK,ZSCAN2,RPS6KA2,CLIP1,PREX2,LIMS2,KANSL3,SLC22A4,SNCA,KIF13A,IZUMO4,JMJD6,DOCK9,AP4E1,CLIP2,NT5M,EPM2A,FAM13C" Drug 3220_UP Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "CDC42BPA,KCNAB2,STX16,SYNJ2,BAIAP3,AKAP7,COL9A3,ARHGEF10,SIPA1L1,GREB1,INTS1,EDNRA,APC2,FGFR1,TRMO,FYB1,GAD1,RAB30,GNAL,GRM8,IRAK3,INPP5B,GIT1,TAGLN3,MYCN,MYT1,NPTX1,NTRK2,CDK18,PDE4A,PLCD1,PPP5C,RPS6KA2,SBF1,ASAP3,PREX2,RPGRIP1L,TMEM121,TNS1,CLIP2,SLC30A3" Drug 6470_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "SEMA6A,SRPX,AMH,APC,LDLRAD4,SPAG9,PLAA,NRG2,MFAP3L,TMCC2,DTNA,EDNRA,FEM1B,SUGP2,EGFR,ANKMY1,DISC1,BTN2A1,HSF2,INPP1,KCNH2,IPO5,NF1,NPTX1,PLXNB1,PPARA,MAPK7,SUSD4,KHDRBS2,SAFB,SYBU,FAM214B,ZKSCAN3,DOK5,TROVE2,NXT2,STX1A,THRA,TK2,CABIN1,PLPPR2" Drug 2027_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APOC1,ARNTL,BCL7A,RUNX1T1,FAM189A2,CPS1,C2CD2,CRYM,OSBPL3,HDAC9,RCAN1,TOM1,EDNRB,F8,SUCO,POMT1,ATP2C1,PADI2,NXPH3,ICA1,SCAMP5,MYT1,NELL2,NTRK3,PFKFB3,LRP12,MAPK10,PRPH,CRTAC1,TCP11L1,AP1AR,SH3BP2,ELMO2,DOK5,SPTB,ZC4H2,SYN2,PHF24,PARD3,LAT2,XRCC4" Drug 6182_UP nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "APAF1,SLC4A4,CACNA2D1,CBARP,ASIC3,CHRNA4,PICK1,NCOR2,DAPK3,SEZ6L2,FAM13A,MBNL2,PLXNC1,MRNIP,VPS13B,STX2,OLFM1,FGFR1,BAIAP2,AGAP2,GNAO1,KCNJ5,NEFM,NF1,OPRL1,PDE4D,PFKFB2,PTPRN2,PNMA8A,RASA3,SH3BGR,SH3GL3,FRMPD1,CPEB3,CNKSR2,PDZD2,ZHX3,ICAM5,RPRM,LMF1,JPH3" Drug 900_DN 5186324; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.10E-04 1.00E+00 1.50E-03 1.70E-02 41 199 "BIN1,NUMB,QKI,CREM,DCAF8,LYPD1,SLC12A6,TNK2,F8,FHL1,SEMA4D,EFCAB2,FAM49B,GPD2,GPER1,MAP4K5,JAK2,MAP4,MPP2,GIT1,SMIM7,PMP22,STRN3,MAPK7,CNNM2,TMEM104,PTCH1,ZCWPW1,EMID1,FBXO11,ZSWIM8,EXOC7,PCDHA5,ZNF34,TIAM1,PARD3,HIRA,VAV1,DNALI1,GDPD5,PHTF2" Drug ctd:D014810 Vitamin E CTD 1.10E-04 1.00E+00 1.51E-03 1.70E-02 228 1594 "ACHE,NDRG2,ADCY6,ADD1,AP2A2,OSBPL1A,LTBP4,BIN1,CDC42BPA,APBB2,CDC14B,CDK10,ARHGDIA,CDK13,SLC4A4,ADGRB1,BARD1,BCHE,CFLAR,SYNJ2,SCAPER,THSD7A,CAMK2B,CAMK2G,RUNX1T1,LDB2,CD86,CDC25B,ZBED1,LRRFIP1,SRSF11,CLCN3,TPP1,STOML1,CLTB,RAB26,IQCK,FAM149A,RCHY1,NCOR1,CSNK1E,CSNK1G3,CST3,PPP6R2,TCAF1,DCAF8,ZNF337,DAPK3,RHOBTB1,SACS,SGSM2,SEC16A,USP3,DMTF1,DNM1L,FIS1,E2F6,EDNRA,PHC2,EEF1D,EGFR,AASS,EIF4G1,EIF5,PLEKHA1,USPL1,ENO2,EPB41L2,RASGRP2,ERBB2,DENND4A,SPEG,EZH1,TUBA1B,TUBB3,FECH,FOXF2,VTI1B,SYNCRIP,EVL,NOP56,FOLH1,ZNF44,RAPGEF6,ZNF274,INPP5K,DHRS4,TCERG1,RNPS1,GLI2,POLL,GNG4,ADAP1,GRIA2,GSN,GSTM5,FAM107A,MAP4K5,HBA1,MAN1B1,SYNPO,HNMT,SMAP1,ICA1,IDH3B,ITPKB,KCNH2,KCNJ5,KTN1,LAMP2,PAXBP1,MAP4,MAPT,MBD1,MBNL1,CHST6,TM6SF1,THYN1,MX1,MYO6,HNRNPM,NEK1,NFE2L2,NOVA1,SLC11A2,OPA1,PCDHGC3,PDPK1,PIK3R1,PKD1,RETREG1,PKM,SMOX,MBOAT7,MAPK3,PIGG,TMEM260,PTPRD,PTPRO,TUG1,CEP97,USP47,FAT4,ZCWPW1,RBBP6,KCTD17,SLC25A36,ALG9,RPS6KA2,MAP6D1,CLIP1,ZNF331,S100B,SATB1,ATXN7,GALNT10,FERMT1,KIF16B,ASAP3,AMBRA1,SEC31A,EPN2,SLC6A8,ZNF430,SEPHS1,SLC12A2,RCOR3,TTC17,LIMCH1,SNAP25,USP33,FNBP1,UHRF1BP1L,SPTAN1,SPTB,LMO3,TROVE2,ST5,MPRIP,APOM,SEPT8,NSFL1C,SUPT5H,PRRC2C,MMS19,ANKRD12,PJA1,TAF6,FAM208A,PDLIM2,AGTPBP1,TBL1X,SMG6,KLHL4,ATMIN,WSCD1,KIAA0930,ZEB1,TNS2,DICER1,SIRT1,ITGB3BP,NACC2,CBX5,R3HDM1,PARD3,TNS1,TPM2,WBP2,RUNDC3B,TRO,TSC2,TTC3,RPRM,UBE3A,UCHL1,UGT8,VGF,REEP1,ZNF195,FTSJ1,ZFAND5,UPF3A,EMSY,EVI5,NAV3,ITM2C,FXR1" Drug CID000474412 dGprG2'OMe Stitch 1.14E-04 1.00E+00 1.56E-03 1.76E-02 7 12 "ATP6V0A1,NRP2,SUMF2,FLT1,NPTX1,NPTX2,EXOSC10" Drug 4108_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ASPHD1,ALCAM,ALK,AMPD3,GAS7,ATP2B2,CLGN,TAOK2,WHRN,ABCG1,AATK,SNCAIP,PDE4DIP,EXOG,ENO2,EPHB1,CSPG5,GNAO1,BTN2A1,GSTM5,ATXN2L,HLF,ICA1,ITGA7,KCNN1,LSS,MATN3,ADAM22,PALM,LRP12,MAPK7,SH3BP2,LIMCH1,KIAA1107,SZT2,HIF3A,TRIO,LAT2,SLC30A3,SLC17A7" Drug 6587_UP AG-028671 [847803-03-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ABR,ALCAM,STX16,CFLAR,SPAG9,TAOK2,QKI,PDE4DIP,DAPK3,DTNA,FCF1,OPTN,HSD17B14,ZNF589,ANKFY1,PDLIM5,ARFIP1,HTATSF1,MAP4K5,LSS,MMP16,ZNF862,NFYA,CNOT4,PLEC,TRIM68,RNASEL,ASAP3,ELMO2,RCOR3,SS18,ST5,CHST8,TPM1,UBE2H,VLDLR,SH3GLB2,UBE3B,RNF170,FXR1" Drug 201_UP 15d-PGJ2; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "NDRG2,KIAA1324,BEGAIN,ARNTL,SLC4A4,CACNA1I,CFAP410,CNTN1,NCOR1,C2CD2L,HS3ST2,DYNC1I1,DRP2,TOM1,DCTN4,FECH,BAIAP2,BTN2A1,PADI2,KIF5A,MBP,ADAM22,PFKFB2,CNNM2,ZSCAN32,RAD51D,RBBP6,ASAP3,CHD9,FNDC3A,ELMO2,LMO3,ANKRD28,SIN3B,TSN,UBE3A,ZNF142,ZFAND5,SLC17A7,MPPE1" Drug 3028_DN Moxalactam disodium salt [64953-12-4]; Down 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "PKP4,APAF1,NCOA1,CAMK2G,CBFA2T2,QKI,HOMER3,SLITRK5,RUBCN,TBC1D5,DBT,DCTN1,NR1D2,DTNA,FIS1,HIPK3,FCF1,GPHN,PDLIM5,MPP6,GPD2,GRB10,NCKAP1L,ITGAM,LIG4,SMAD1,NF1,NFYA,SLC25A23,TMEM231,TRIM68,GTDC1,C12orf49,NSFL1C,EXOC7,TCF4,KAT6B,CABIN1,LAT2,EMSY" Drug 1768_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ACTN1,BRAP,APBB2,ARNTL,SYNJ1,FUBP1,WASF1,KRIT1,ZNF337,DTNA,KCTD3,DENND4A,VPS26C,ST3GAL6,SEC23B,KTN1,AFF1,NUCB2,OPA1,PIK3C2A,ZNF426,TRHDE,STRN3,RETREG2,PPM1B,CLIP1,ATXN7,FBXO11,WDR47,HECW1,RBM26,POGZ,ITPRID2,ERBIN,NXT2,CEP68,AGTPBP1,WIPF1,EVI5,RTN4" Drug 2829_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "BIN1,CDC42BPA,APBB2,PPFIA3,SLC4A4,CFLAR,BAIAP3,SLC16A4,ARHGEF2,RCBTB2,STOML1,CSF1R,GREB1,MAML1,ARMCX2,SEZ6L2,ANKMY1,FGF13,FGFR1,HPGDS,ITPKA,ITPKB,IPO5,MIA2,ADAM22,NNAT,MBOAT7,LRRN3,RELN,SNRK,CCDC40,RORB,ASAP3,PREX2,PEX26,SOX3,CDK19,TROVE2,WSCD1,SLC30A3" Drug 367_DN "ICI 182,780; Down 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "OGT,CDK13,FUBP1,RAB29,CFAP410,CA12,DLGAP1,LHX2,GREB1,RCAN1,E2F5,HIPK3,RASGRP1,EGFR,MBNL2,EGR3,CALCRL,GPHN,FGFR3,IQCG,PDLIM5,NSG1,OGA,ZNF276,LILRA2,MAP4K5,IL6ST,JAK2,KITLG,ADAM22,MYO6,SDK2,C1orf109,GAL3ST4,AP1AR,SH3GL3,SLC8A1,SNAP25,TBL1X,UBE3A" Drug 1961_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ABHD6,NDRG3,BIN1,SLC4A4,BLM,CFLAR,PTBP2,CAMK2B,NFS1,ARHGEF2,TAOK2,EPS15L1,DCAF8,ZFYVE16,SPOCK2,DTNA,ETV1,ZNF589,USP21,OGA,ERAP1,PCLO,GRB10,GRIK5,MAP4,NEK1,MAPK3,CNNM2,PTPRE,GTDC1,RIC8B,SUPT20H,SLC11A1,SMARCA4,UNC5B,ATP10B,CEP68,SYNE2,TRIO,HSPBP1" Drug 4835_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "NME5,RGS20,SYNJ2,MTMR3,BAIAP3,HAP1,CBFA2T2,ARHGEF2,CLGN,QKI,NECTIN3,CREM,CYBB,ARMCX2,FBXL5,EGR3,COQ7,RASGRP2,SPEG,AGAP2,PDLIM5,FYN,DISC1,GATM,GRB10,ATXN2L,LMO2,MID1,SERPINI1,MAPK7,RPS6KA2,CCDC88A,ARC,EXOC7,RPGRIP1L,PCDHA6,AP4E1,VLDLR,XRCC4,SLC30A3" Drug 5764_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ACTN1,ARRB2,MYRF,FOXN3,ASIC3,B4GALT6,SULT4A1,FAM13A,HSD17B14,VPS26C,EZH1,ST3GAL6,DISC1,GLYR1,GIT1,ADAM22,ZNF862,NF1,SERPINI1,RETREG1,NLE1,CNNM2,PTX3,TMEM231,SH3TC2,FAM184A,GAL3ST4,KCTD17,KIRREL1,SH3BP2,SLC2A5,MYH15,LIMCH1,ZNF415,ARHGAP26,TIAM1,BEX4,CABIN1,TNS1,TPM2" Drug 4208_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ADCY6,BIN1,APAF1,APC,CFLAR,HAP1,CBFA2T2,SCARB1,SYNGR3,TPP1,RAB26,HOMER3,AKAP5,CREM,MAML1,ING4,ZNF589,OLFM1,IQCG,PDLIM5,GPER1,BACH2,KIT,GIT1,ADAM22,NTRK2,NTRK3,PCDH9,PLCD1,POU6F1,GDPD2,RASA3,ZNF334,SMARCD3,ZSWIM8,TBCEL,RPGRIP1L,BEX4,ZKSCAN5,SLC17A7" Drug 2894_DN Thiamine hydrochloride [67-03-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "NME5,C1QTNF3,SEMA6A,EPB41L5,ARHGDIG,NUMB,RASL11B,CFLAR,ARHGEF2,GREB1,EXOG,ING4,FGFR1,SEMA4D,USP19,GRB10,TJAP1,ITPKB,IPO5,TM6SF1,MITF,ADAM22,ZNF862,PCDH9,LRP12,MAPK10,TMEM104,TCP11L1,CLIP1,SLC6A8,LIMCH1,CLSTN2,THSD1,KIAA0930,CDK20,VGF,VLDLR,ZNF24,SEMA3B,EPM2A" Drug 5628_DN Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ALCAM,AMT,EPB41L5,FAM131A,MARK4,SLC4A4,ARHGEF2,FOXN3,STOML1,DTNA,PHF20L1,COQ7,FAM198B,FGFR1,CACFD1,IL6ST,KIF2A,MPP2,NFYA,OGG1,CCSER2,NLE1,SLC25A23,LRP12,PRODH,PRPH,NKAIN1,CEP97,ZCWPW1,RGS12,SBF1,ABLIM3,EPN2,SUPT5H,TBL1X,DMXL2,TK2,CDK20,FAM155A,SLC17A7" Drug 2283_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ADGRF5,SEMA7A,GAS7,PDE8B,N4BP2L1,CACNA1I,CAMK2B,CD86,CLTB,NCOR2,DAPK1,RUSC2,SPOCK3,FRY,ZNF589,SIGLEC8,GDF9,GPER1,GRM8,HLF,MATN3,MBP,PFKFB2,PLCB2,PTPRN2,FAT4,GAL3ST4,TCP11L1,SLA,SLC2A5,KDM4B,SYT5,WSCD1,SLC35G2,TNS1,TUBB1,FLRT2,LAT2,MKRN3,KCNAB1" Drug 2852_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "NDRG2,CDC42BPA,CDC14B,PLA2G4C,CDK13,CFLAR,CA4,NECTIN3,PDE4DIP,DCAF8,DBT,EXOG,DMPK,DUSP9,CELSR3,STX2,EZH1,FAM49B,SRCAP,STON1,ICA1,IL6ST,INPP1,KCNH2,LIFR,MITF,NF1,PCDH9,SLC25A23,LRP12,MBOAT7,MINDY2,CCDC40,SEC14L1,NUBPL,KIF13A,SOX3,IQSEC2,ZKSCAN5,ITM2C" Drug 5624_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "SPARCL1,N4BP2L1,SEPT7,CACNA2D2,LHX2,NCOR2,CSF1,VCAN,SNPH,GIT2,EDIL3,ING4,REEP2,DLC1,ZNF589,NSG1,GPR162,POLL,ATXN2L,FXYD7,NOVA1,PCDH9,CDK18,PDE4D,PLCB2,MTRF1L,MAPK10,ZSCAN2,KCNIP1,ZNF821,SLC11A1,TSNAXIP1,RBM26,SYT5,WSCD1,CRTC1,PIK3R5,OSBP2,WIPF1,DNALI1" Drug 6734_DN Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-04 1.00E+00 1.58E-03 1.78E-02 40 193 "ADRB2,BIN1,CACNA1I,SOCS6,NRXN3,RAB26,HOMER3,ARHGEF10,PDE4DIP,MFAP3L,SPOCK3,SUGP2,EGFR,MRNIP,MTSS1L,FYB1,ZNF44,TDRKH,GPER1,MEF2C,SCAMP5,PLCD1,PLXNB1,PTCH1,PTN,PTPRN2,PTX3,MSANTD2,FBXW7,SUPT20H,AMBRA1,CDK5RAP2,ELOVL4,PHLDB1,ASTN2,PCDHA5,ZNF34,TNS1,NAV3,AAAS" Drug 3244_DN Corticosterone [50-22-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.22E-04 1.00E+00 1.66E-03 1.87E-02 39 187 "CFLAR,SCAPER,CA12,QKI,ABCG1,GREB1,RHOBTB1,RASGRP1,EGR3,DLC1,FGFR1,EFCAB2,COPS8,KCNMB4,TJAP1,JAK2,KCNF1,MAPT,MPP2,PIK3R1,SMOX,CNNM2,ELOVL2,RBBP8,RET,SLC25A36,RPS6KA2,MAP6D1,SBF1,SGK1,FAM102A,ARFGAP1,POGZ,EXOC7,KAT6B,HIRA,WIPF1,FTSJ1,SEMA3B" Drug 4463_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.22E-04 1.00E+00 1.66E-03 1.87E-02 39 187 "ADGRF5,APAF1,ZBTB10,CACNA2D2,SRSF11,ABCG2,CNR1,PUM1,SEC14L5,NR1D2,DTNB,ETV1,OGA,ERAP1,DISC1,GFER,STON1,LPAR4,GRM2,GSTM5,IL6ST,LAMA2,MAP2,MMP16,PDE4B,SERPINI1,PRKAB2,MAPK7,MASP1,MARCH1,RET,CNKSR2,ZNF334,ARHGAP26,PLCB1,KIAA1107,PCDHGA10,TK2,PLSCR4" Drug 5438_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.22E-04 1.00E+00 1.66E-03 1.87E-02 39 187 "ADORA1,TRMT9B,ASPA,SCAPER,EPS15L1,CPS1,SNPH,MFAP3L,PLPPR4,DMPK,SLC12A6,EGFR,ELN,C3orf18,MTSS1L,ETV1,TPPP3,ERAP1,MAP4,ADAM22,NF1,NOVA2,MTRF1L,PLXNB1,PTCH1,ELOVL2,PTPRN2,C1orf54,RPS6KA2,SEMA6D,SLC2A5,SNCA,DOK5,HECW1,MTCL1,TRIM2,SZT2,R3HDM1,FAM155A" Drug CID000006035 bromodeoxyuridine Stitch 1.23E-04 1.00E+00 1.66E-03 1.87E-02 67 376 "MAP4K3,ATP2A2,BLM,PROM1,CALB1,CALB2,CDH2,TIGD7,QKI,COL11A2,AHCTF1,DMD,MAMLD1,EGFR,ENO2,ERBB4,ERCC2,F5,FKTN,PPP1R1B,FGF1,FGFR1,FLT1,AFF2,NELFCD,CHL1,GAD1,GALC,NEU3,MSTN,AHDC1,IGF1,ITGA7,L1CAM,MAP2,MBP,ADAM11,KITLG,PPM1L,MSI1,MYO7A,NCAM2,NPY,NOVA2,NTRK3,CDK18,PLCB2,FXYD1,PPP5C,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RELN,GSTCD,S100B,SPP1,TSPYL2,DDN,SIRT1,TK2,ACTR6,NPDC1,ZIC1,HNRNPA3,FXR1" Drug 5094_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ADD2,KCNAB2,MARK4,ADGRB2,FUBP1,SLC4A8,DAPK3,SPOCK3,SGSM2,FCF1,MBNL2,BAIAP2,FAM49B,ERAP1,TDRKH,AGFG1,KCNN1,LIFR,MAP4,MATN3,MIA2,CNOT4,SMIM7,KLK6,CNNM2,RAD51D,ZDHHC14,ZNF671,SUPT20H,PPP4R3A,CCDC88A,ZNF415,PEG10,ARHGEF9,EXOC7,TCF4,LMF1,ZNF711,SLC17A7,KAT6A,AAAS" Drug 7329_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ASPHD1,NDRG2,NME5,APAF1,SEMA4G,RASL11B,SLC4A4,ALDH7A1,NRP2,SCAPER,BAIAP3,ARHGEF2,CSF1R,RGS6,TBC1D5,MFAP3L,PARD6A,MBNL2,ING4,RRAGB,AGAP2,PRELID3A,MALT1,RAB30,GRIK5,CACFD1,SMAD1,MMP16,CNOT4,PDE4B,MAPK10,RGS12,ZFHX4,EMID1,SYBU,PKNOX2,SLC11A1,LIMCH1,PLCB1,AMACR,ST7" Drug 6405_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "PDE8B,NRP2,CFAP410,CALB1,LY86,PCYT1B,PDE4DIP,ARHGAP24,RASSF2,MFAP3L,HIPK3,LRRC17,NCALD,SPEG,F5,PTK2B,FGFR3,SEPT9,ALDH1L1,HLF,MAP2,AFF1,MSI1,ADAM22,TAGLN3,PCDHGC3,PFKFB2,SMOX,SLC25A23,PLTP,LRP12,ZNF493,RNASE1,RTN1,HECW1,MCF2L2,TCF4,DOCK9,TPM2,SLC30A3,PHTF2" Drug 5853_DN Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ACTN1,ADD1,BRAP,SHROOM2,NCOA1,SLC4A4,ALDH7A1,C5,CA12,HIP1R,LARGE1,CNOT8,CNTNAP2,SPATA2,KLHL3,SUGP2,IRAK4,ING4,STX2,SPEG,TRAF3IP2,DISC1,INPP5K,ZNF276,GNG4,RASSF8,PDE4D,ELOVL2,PTN,ZSCAN32,GTDC1,SH3GL3,ST6GAL1,POGZ,IQCE,CBX5,HIRA,PLPPR2,XRCC4,SMIM8,PHTF2" Drug 4525_DN Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "BRAP,APC,CDC14B,SYNJ2,SCAPER,RCBTB2,RAB28,AKAP7,HAPLN1,DBN1,DBT,EXOG,EDNRA,FCF1,ERCC2,PRELID3A,SYT17,USP19,GPD2,RASSF8,SCIN,MAPT,NDP,CNOT4,PPP5C,ELOVL2,PID1,FBXW7,TRAPPC13,AMBRA1,DZIP1,FAM214B,SS18,ASTN2,ZMAT3,UGT8,WIPF1,XRCC4,NT5M,HPS4,NAV3" Drug 7456_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "FZD9,LTBP4,AMH,BIN1,APC,ARRB1,SCAPER,GYG2,SEPT7,CRLF1,FOXN3,SOCS6,ENTPD4,NCOR2,TBC1D5,MFAP3L,SLC12A6,RCAN1,MRNIP,AFF2,OGA,SYT17,CSDC2,GRIN2C,TJAP1,ITPKB,KCNN1,MATK,SLC11A2,NTRK2,PALM,PDPK1,PLXNB1,PPP2R2B,WDR25,RPS6KA2,SEMA6D,SBF1,TSNAXIP1,TEK,SLC30A3" Drug 3827_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AK2,DOC2A,GAS7,BAIAP3,PLEKHB1,LHX2,STOML1,RAB26,AKAP5,AATK,EDNRB,ETV1,DLC1,FGF1,DCTN2,FYB1,TRAF3IP2,ITGA7,KIFC3,LAMA2,LYRM9,ZCWPW1,SBF1,SLC2A5,SLC6A11,SLC9A5,ZNF334,OGDHL,KDM4B,SOX15,ZHX3,LHPP,PLCB1,MCF2L,EXOC7,CHST8,TRIO,FLRT2,VLDLR,REEP1,DPF3" Drug 5755_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "SEMA7A,APBB2,APC,APOC1,CAMK2B,PLEKHB1,ARMC8,WHRN,SNCAIP,CSNK1E,ARHGAP24,DTNA,ING4,IGSF6,REEP2,HPCAL4,COPS8,GSTM5,SOX21,PADI2,ICA1,SHISAL1,LMO2,AFF1,NELL2,NF1,NOVA1,NTRK2,PDE4D,PFKFB2,STUM,PPP4R3A,PKNOX2,ARHGEF40,SLC12A4,TSNAXIP1,IQSEC2,PLCB1,ASTN2,ZNF225,KCNAB1" Drug 2449_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "NDRG3,KCNAB2,ARRB1,ADAM23,NRP2,BMP7,CA8,THSD7A,RAB26,CNTFR,CNTN1,ARHGAP32,SV2B,HIPK3,FCF1,CNNM1,HEYL,MBNL2,C3orf18,EIF1,KAT8,HPCAL4,ANKFY1,ERAP1,KCNH2,MAP4,MBP,AFF1,NPTX1,PDE4D,PFKFB4,PKIA,PTPRN2,PID1,BEND5,ZNF821,ZNF667,SS18,EXOC7,CHST5,KCNAB1" Drug 6246_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "LTBP4,ALK,DOC2A,AMPD3,ATP2A2,AZGP1,SYNJ2,SCAPER,SGCE,CA12,PLEKHB1,STOML1,RCAN1,ACSL4,SRCAP,GLYR1,SLC2A6,MUM1,HLF,IL6ST,INPP5B,ITPKB,KCNH2,MAP4,ADAM11,MIA2,NF1,RETREG1,ZCWPW1,KCTD17,GSTCD,RPS6KA2,SH3BP2,ZSWIM8,ZC3H13,CABIN1,HIRA,VIPR2,LMF1,HPS4,TIGD6" Drug 3240_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ADD1,ALCAM,FAM131A,APOC1,BAIAP3,CAMK2G,LHX2,COL4A5,CREM,ENTPD4,CSF1,MAML1,GIT2,DBT,LYPD1,MTSS1L,STX2,F8,GALC,USP19,POLL,TDRKH,STON1,ICA1,KCNQ3,MMP16,ZNF862,NF1,PLEC,COA1,KDM4C,UNC5B,CDK19,SPART,POGZ,ARHGEF9,PLCB1,EXOC7,TK2,RUNDC3B,EVI5" Drug 5311_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "C1QTNF1,PLA2G4C,SLC4A4,STX16,KIF1A,BMP7,KYAT1,CRY2,PDE4DIP,GREB1,ARHGEF4,HSD17B14,BAIAP2,PRKAG2,AHDC1,GLYR1,ATXN2L,HNMT,ICA1,LSS,MAP2,GIT1,LYRM9,CNOT4,NTRK2,P2RY1,PDPK1,WDR25,SYBU,SLC6A8,KDM4C,EXOC7,TNS2,PLPPR2,LMF1,ZNF24,UPF3A,MAP3K12,GDPD5,HPS4,PCBP4" Drug 2759_DN Cytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AK2,C1QTNF3,CDC42BPA,APBB2,NCOA1,BMP7,CA12,CNOT8,EPS15L1,CREM,GREB1,SPATA2,PARD6A,DTNA,HIPK3,ZNF589,POLR1B,FGFR1,DISC1,RAB30,MSL3,CACFD1,BTN2A1,INPP5B,MITF,SLC25A23,RETREG2,GTDC1,RNASEL,GSTCD,CLIP1,ELMO2,SLC22A4,COA1,SPTAN1,PCDHA6,TRIO,UBTF,CLDND1,ST7,UBE3B" Drug 4202_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AP2A2,ALK,AMPH,APAF1,APC,CACNA2D1,HAP1,CAMK2B,SCARB1,ENTPD2,RAB33A,TPP1,HOMER3,ABCG1,PDE4DIP,SPOCK2,DBT,ETV1,ZNF589,DCTN2,TRMO,PDLIM5,B4GALNT1,DISC1,PADI2,ATXN2L,MEF2C,LYRM9,NF1,SETD4,LRRN3,PPP5C,ELOVL2,PTPRN2,GAL3ST4,RGS4,TCP11L1,PREX2,ARHGEF40,SLC14A1,RPGRIP1L" Drug 5762_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "TRMT9B,CDC42BPA,PRX,SCAPER,GYG2,HAP1,SYNGR3,PLEKHB1,NRXN3,RAB26,HOMER3,CRMP1,RIPOR2,MYEF2,MFAP3L,C2CD2L,SPOCK3,DTNA,ING4,DENND2A,RUNDC3A,COPS8,GSTM5,SMAD1,MATN3,NPR2,CEP41,PTN,FAT4,SUPT20H,PKNOX2,ASTN2,TBCEL,TMEM121,ZFPM2,TNS1,TRO,CA14,VAV1,ZNF24,SLC17A7" Drug 5991_UP Phenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "SYT13,KCNAB2,PPP4R4,RCBTB2,FAM189A2,ARHGEF6,SMARCAL1,TMCC2,DTNA,EGFR,TENM1,VPS13B,RASGRP2,CORO2B,FGFR3,FHL1,ALDH1L1,GFER,IRAK3,KCNH2,KITLG,MMP16,ADAM22,RETREG1,NECAB2,TMEM231,KLHDC8A,CARF,TCP11L1,EMID1,ASAP3,SYBU,SLC8A1,SLC22A4,SMARCD3,KDM4C,PLCB1,SLC44A1,CABIN1,RUNDC3B,LAT2" Drug 2481_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ADORA1,APBB2,SEMA4G,PDE8B,KIF1A,KSR1,BMP7,CACNA1I,CA12,COL9A3,ABI3BP,NCOR2,SIPA1L1,DCAF4,RIPOR2,MFAP3L,CDON,OPTN,ERBB2,OLFM1,FGFR1,GRM2,GRM8,KCNJ5,KCNQ3,KHK,MEF2C,MMP17,NEFM,PDE4D,PMP22,STRN3,MAPK7,RGS4,KCTD17,TCP11L1,EMID1,SSTR2,PHLDB1,CRTC1,FAM155A" Drug 6523_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "FZD9,AK2,BEGAIN,RGS20,CFAP410,CBARP,CHRNA4,CNN3,AKAP7,CNTNAP2,SPOCK2,RCAN1,DTNA,PLXNC1,CORO2B,FGFR1,FHL1,FYB1,SIGLEC8,RUNDC3A,GNAO1,LPAR4,GRIN2C,GRM8,KCNJ5,MAP4,MSI1,PDE4B,GPR85,PTCH1,PKNOX2,ARHGEF40,CLSTN2,PLCB1,ZEB1,PCDHGA10,SLC44A1,WIPF1,SLC30A3,DNALI1,KCNAB1" Drug 418_UP haloperidol; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AGT,APOC1,PPFIA3,N4BP2L1,SYNJ2,CACNA1A,CBFA2T2,TPP1,CSF1,CSF1R,DRP2,DTNB,FEM1B,EPHB1,NRN1,FOLR2,NSG1,LUZP2,FAM107A,ATXN2L,MMP17,GPR173,CCSER2,FXYD1,CEP41,MASP1,FAM184A,ENOX1,CRTAC1,ATXN2,ZNF821,FNDC3A,KBTBD4,ELMO2,ADGRL3,ZNF34,TNS1,PDIA2,WNT7A,UPF3A,SLC17A7" Drug 6167_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "SYN3,SPARCL1,BIN1,CDK10,PDE8B,SLC4A4,PROM1,SYNJ2,CACNB4,LARGE1,DLGAP2,SLIT2,CSNK1E,DAPK1,CDON,MBNL2,RASGRP2,F5,REEP2,FGFR1,SEPT9,INPP5K,GPD2,GRIK5,KCNB1,KPNA5,MSR1,NF1,NOVA2,CLDN11,CCSER2,PTPRB,PTPRN2,GALNT10,FRMPD1,CPEB3,SP4,SYT5,IQCE,RIMBP2,RPRM" Drug 3078_DN Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AP2A2,C1QTNF3,APAF1,APC,MARK4,RIPK1,CAPN3,CBR1,SLC16A4,SCARB1,SOCS6,TPP1,CLOCK,DTNA,FAM13A,SEC24B,EVL,FYB1,TRAF3IP2,ERAP1,DISC1,INPP5K,LILRA2,PCLO,LAMA2,SETD4,STRN3,MINDY2,PPP3CC,TCP11L1,PPM1E,KDM4B,SPTAN1,SZT2,SYNE1,SIK3,KAT6B,NPDC1,TFIP11,KCNAB1,UBE3B" Drug 3569_UP Tropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AMT,KCNAB2,MARK4,GYG2,CFAP410,CBFA2T2,EPS15L1,COL9A3,CSF1R,DCAF4,SPOCK2,DMPK,DTNA,GPER1,KCNH2,MGAT3,MX1,NF1,SLC25A23,CEP41,RELN,ZSCAN2,RGS12,TCP11L1,RPS6KA2,TRA2B,FBXO11,SLC9A5,COA1,SNCA,SPTAN1,CLSTN2,ARC,TBCEL,PCDHA6,CHST8,ZNF34,SLC44A1,EVI5,KCNAB1,PHTF2" Drug 2169_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "NDRG2,ADD2,CDC42BPA,APBB2,DNAH17,SLC16A4,CBFA2T2,SOCS6,B4GALT6,ABCG1,CRYM,AATK,SIPA1L1,DAPK1,MFAP3L,EDNRB,ELN,EIF1,ERBB2,SCML2,FLT1,SEPT9,PCLO,KIT,MYO6,NOVA2,PDE4D,PLCD1,PPP3CC,BCAS3,ZMAT4,SEC14L1,SLC11A1,SPTB,IQSEC2,ZBTB43,STX1A,TBCEL,RPGRIP1L,RPRM,SPHK2" Drug 3008_DN Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "BRAP,AP2A2,APBB2,ATP2A2,NRP2,KSR1,SLC16A4,SCARB1,CHRNA4,PDE4DIP,ZNF337,BRINP1,KIAA0753,MBNL2,EPB41,PIPOX,PRKAG2,EFCAB2,SEPT9,ADAM28,ITGAM,KPNA5,LSS,MAP4,AFDN,NINJ2,NPR2,ZSCAN32,GTDC1,PLPPR3,FRMPD1,AMBRA1,NLGN1,EPN2,SNAP25,SYT5,IQCE,TCF4,OBSL1,LMF1,PHTF2" Drug 3003_UP Reserpine [50-55-5]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "C1QTNF1,MYRF,CFAP410,CALB1,SULT4A1,RAB26,ARHGAP32,MFAP3L,EGR3,TNK2,MRNIP,ERBB4,OLFM1,AGAP2,SRCAP,POLL,GRIK5,CACFD1,RNFT2,ATXN2L,SCIN,NFIX,OXTR,PCSK5,PDE1C,PFKFB2,PLCL1,FSD1,RGS4,NEK11,ASAP3,PREX2,KDM4B,ZSWIM8,ZC3H13,SYT1,TIAM1,RUNDC3B,VGF,SPHK2,HRASLS" Drug 1829_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "NUMB,CARS,AP4M1,ZMYM4,FOXN3,ARHGEF6,IQCK,CDC42BPB,CTH,PPP6R2,SGSM2,SUGP2,VPS13B,FHL1,POMT1,ATP2C1,SEPT9,GLUL,MARK3,PDCD2,PPP3CC,PRKAB2,PRKACB,BCAS3,TMEM104,ROGDI,EPN2,KBTBD4,SMARCC2,TMCC1,GLT8D1,UHRF1BP1L,SUPT5H,WSCD1,PARD3,TSC1,HIRA,PLPPR2,TFIP11,UPF3A,ST7" Drug 6836_UP Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "BIN1,APOC1,SLC4A4,SLC2A11,CACNA1A,CD86,ARHGEF2,RCBTB2,AKAP7,RCHY1,NCOR2,VCAN,DCAF4,SNPH,RUSC2,DUSP9,RASGRP2,ZNF391,ANKMY1,REEP2,ACSL4,DLC1,NSG1,SIGLEC8,ALDH1L1,PCDH17,GRIK5,AP4S1,AFF1,MMP16,TAGLN3,MTRF1L,DIRAS2,RASA3,ASAP3,FAM214B,SLC14A1,ARC,WSCD1,UCHL1,VIPR2" Drug 1443_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ARNTL,ARRB2,CAMK2G,RUNX1T1,CREM,CSF1R,OSBPL3,SLITRK5,STX2,CD320,FCGRT,FECH,PRKAG2,MPP6,ERAP1,RAB30,MAN1B1,ELOVL5,POLR2F,PPP2R2B,MAPK10,PTK2,CCDC40,RGS12,NCBP3,KBTBD4,ELMO2,FNBP1,DBNDD2,LMO3,CLASP2,ST5,CEP68,SYT1,PHF24,ZMAT3,CHST5,TSC2,MPPE1,SMIM8,ACTR3B" Drug 5513_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ADRA1D,TRMT9B,GAS7,PDE8B,ALDH7A1,SCAPER,CACNA1I,RAB29,SPAG9,CLGN,MFAP3L,RUSC2,EPHB1,FHL1,FYB1,GPD1,ADAMTS13,GRM2,GRM8,BTN2A1,LIG4,SMAD1,MAP4,MSR1,NEFM,NF1,NNAT,MTRF1L,STRN3,GRAMD1C,ZDHHC14,GTDC1,OGDHL,STX1A,SYN2,TACR1,MCF2L,DOCK9,TRPM2,KCNK12,XRCC4" Drug 7229_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ASPHD1,CDC42BPA,EPB41L5,BCL7A,CFLAR,MTMR2,C5,SYNGR3,CRLF1,ARHGEF6,COL4A5,FAM169A,FBXL5,PARD6A,RCAN1,EDNRA,CDKL3,EZH1,SEMA4D,SMC2,B4GALNT1,SYT17,GPR37,GRB10,HNMT,INPP5B,MAP4,MAPT,SETD4,STRN3,LRP12,SAMD9,TMEM104,RIPOR1,SBF1,PPP4R3A,ARFGAP1,POGZ,NSFL1C,TRIM2,TFIP11" Drug 4783_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ADCY6,DOC2A,MAP4K3,APBB2,GYG2,CFAP410,ARHGAP33,HOMER3,SH2B1,CSNK1E,PDE4DIP,DCAF8,DBT,EDNRA,FECH,ERAP1,GNG4,ELOVL5,HNMT,MAP4,MATK,MIA2,MITF,SLC11A2,PLXNB1,PPP2R2B,PRODH,SAMD9,WDR25,NKAIN1,RGS3,RNASEL,SH3BP2,ABLIM3,TMCC1,IQSEC2,TTBK2,ASTN2,XRCC4,MPPE1,PHTF2" Drug 5842_UP Ketotifen fumarate [34580-14-8]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "MTUS1,BIN1,CFLAR,CFAP410,FOXN3,CNOT8,COL9A3,SH2B1,PDE4DIP,DCAF4,GIT2,KIAA0753,EDN1,TUBD1,PTK2B,ST3GAL6,FGF1,SEMA4D,TRMO,SYT17,GLUL,JAK2,MIA2,NF1,POLG,PTPRE,FAM184A,BEND5,KHDRBS2,TCP11L1,CLIP1,MRAS,KBTBD4,SMARCA4,TMCC1,NMNAT2,NFASC,IQCE,DOCK9,TMEM121,KCNAB1" Drug 4002_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "AP2A2,DOC2A,AMH,KIF1A,ADAM23,KSR1,BAIAP3,CALB2,THSD7A,CLDN10,TPP1,ENTPD4,CRY2,SUSD5,RIMS2,TENM1,NSG1,OGA,GNAL,LILRA2,CACFD1,IL12A,KCNF1,MARK1,NEFM,NLE1,PPP2R2B,BEND5,PNMA8A,CCDC102B,MRAS,FUZ,HECW1,NFASC,PHLDB1,KLHL4,SLC44A1,CHST5,FLRT2,VGF,ZNF225" Drug 2995_UP Theobromine [83-67-0]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.23E-04 1.00E+00 1.66E-03 1.87E-02 41 200 "ABHD6,AMPH,BCAS1,CFAP410,HAP1,NRG2,HAPLN1,ABCG1,CSF1,CNTNAP2,DZIP3,GPRASP1,RIPOR2,FAM13A,EGR3,EIF1,DLC1,FLNC,GLYR1,SPACA9,ATXN2L,KHK,LAMA2,AFDN,PDE4D,CCSER2,BCAS3,PTPN13,NEK11,LIMS2,KDM4B,SYT1,SMG6,TK2,TPM2,TRPS1,SSBP2,KLC2,SPHK2,ZBTB38,FZD3" Drug CID000059708 etiracetam Stitch 1.25E-04 1.00E+00 1.67E-03 1.89E-02 18 62 "ADORA2A,AMPH,PROM1,CACNA1G,CBS,CREM,CST3,SV2B,GPHN,GAD1,POLL,GRIA2,GRM8,MEST,ABCB1,SLC6A11,ICAM5,EPM2A" Drug CID000001248 AC1L1B1W Stitch 1.27E-04 1.00E+00 1.71E-03 1.93E-02 22 84 "ADORA1,SULT4A1,DCTN1,DTNA,GPHN,CSPG5,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,MAP4K5,SALL1,SLC6A11,SLC12A2,ARC,ZEB1" Drug CID000004799 AC1L1IZE Stitch 1.27E-04 1.00E+00 1.71E-03 1.93E-02 30 131 "ADORA1,ADORA2A,ADRA1D,APC,DNAH17,DYNLL1,ATP2A2,ATP2B2,KIF1A,KRIT1,P2RX6,ENTPD2,DNAL1,DNAH9,ATP2C1,LPAR4,DDX19B,KCNK3,SMAD1,KITLG,MYO7A,P2RY13,P2RX7,P2RY1,OLA1,MAPK10,RYR3,MAPK12,P2RY12,DNAH10" Drug 3290_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.28E-04 1.00E+00 1.72E-03 1.93E-02 38 181 "APOC1,BCL7A,CA12,LRRFIP1,CSNK1E,GREB1,SACS,TSPAN5,EGR3,TBC1D16,RACK1,SEMA4D,FAM49B,CAMKK2,MSL3,PRRC2B,GRB10,ITPKB,KCNH2,MAP4,MIA2,MMP16,NRCAM,PDCD2,PMP22,ELOVL2,MAP6D1,SPTAN1,CDK19,ATMIN,ZMAT3,TIAM1,CBX5,VGF,SLC38A1,EPM2A,FZD3,NETO2" Drug 3819_UP Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.28E-04 1.00E+00 1.72E-03 1.93E-02 38 181 "PRX,NRP2,GYG2,CACNA1I,KALRN,USP2,WHRN,ZNF804A,RUSC2,EZH1,BAIAP2,FLT1,AFF2,PDLIM5,PRELID3A,NSG1,B4GALNT1,RAB30,FERMT2,MUM1,MARK1,MYO7A,NCF2,NRCAM,NTRK3,OXTR,PALM,GPR85,HSPA4L,HKDC1,KIF13A,TRIM2,SYNE1,WBP2,UBE3A,UCHL1,SPHK2,NAV3" Drug 4260_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ACHE,SYT13,AMPD3,DDO,SYNJ2,BAIAP3,USP2,FOXN3,NRXN3,FAM149A,CABP1,COL9A3,RGS6,CNTNAP2,TNK2,DLC1,AFF2,SIGLEC8,GNAL,GNAO1,GRIK5,SOX21,ATXN2L,LSAMP,PACRG,ADAM22,NF1,NTRK3,PDE4D,DUSP26,RASGRF1,KHDRBS2,GAL3ST4,ZMAT4,RNASEL,RASA3,DDN,PCDHA5,TRO,KCNK12" Drug 2886_DN Prenylamine lactate [69-43-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "APBB2,APOC1,ATP2A2,SYNJ2,MTMR2,ASIC3,B4GALT6,VAX2,SOCS5,APPL1,DCAF4,LYPD1,PARD6A,ZNF589,FGFR3,CINP,GALC,RAB30,INPP1,KCNH2,KHK,KIF2A,MAPT,SCAMP5,MPP2,GIT1,OPA1,PMP22,LRP12,MBOAT7,FA2H,MINDY2,FAM184A,RGS12,KDM4B,SPART,KIAA0930,RPGRIP1L,CDK20,SMIM8" Drug 2087_DN Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ADD1,APC,CFLAR,CCNT1,CNOT8,HOMER3,FAM169A,ARHGAP32,PARD6A,DYNC1I1,EGFR,COQ7,STX2,ZNF589,FGFR1,MAP4K5,IFI16,MPP2,OGG1,LRP12,POLG,TMEM260,RIPOR1,ASAP3,AMBRA1,BTBD7,ERC1,ZBTB43,EXOC7,FBXW11,TBL1X,TRIM2,TNS2,TRIO,HIRA,NPDC1,UPF3A,NT5M,SEMA3B,EPM2A" Drug 5855_UP Harmine hydrochloride [343-27-1]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "SPARCL1,CDK13,N4BP2L1,ADAM23,SRSF11,SOCS6,ARHGAP22,NRXN3,CREM,SH2B1,HAPLN1,PDE4DIP,C2CD2L,CDKL3,VPS26C,RACK1,GLYR1,GPR37,KIT,NF1,NOVA1,NTRK2,PPM1B,PRKAR1B,MAPK7,TMEM231,FBXW7,RPS20,ASAP3,ANKRD6,KDM4D,SNAP25,ZBTB43,ATP10B,ZFPM2,CBX5,VIPR2,WIPF1,KCNAB1,DPF3" Drug 5854_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ACTN1,BRAP,MTUS1,APBB2,APLP1,PTBP2,HOMER3,SOCS5,DZIP3,ZNF337,SPATA2,FBXL5,RHOBTB1,MED12,DYNC1I1,SUGP2,F8,ACSL4,FGF13,POMT1,SESN1,COPS8,SLC2A6,MUM1,KIF2A,SCAMP5,MID1,CCSER2,MAPK3,SNRK,NUDT11,KIRREL1,SH3BP2,ELMO2,SMARCA4,TMCC1,FBXW11,PARD3,NAV3,KAT6A" Drug 7051_UP Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ASIC1,ADCY6,ADORA1,NME5,AK2,AMH,APOC1,PDE8B,KIF1A,CA12,CAMK2B,CAMK2G,ARHGEF1,FAM189A2,INTS1,SPOCK2,C2CD2L,LRRC17,KCNMB4,SPACA9,KCNB1,MAP4,MN1,NF1,TMEM104,GAL3ST4,RPS20,SBF1,SLC2A5,PEX26,PPP4R3A,LIMCH1,CLSTN2,SAMSN1,JMJD6,EXOC7,ZMAT3,LAT2,SLC30A3,SEMA3B" Drug 7545_DN semustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "RALGAPA1,ACTN1,AP2A2,APC,MARCH3,ARHGEF1,LHX2,SULT4A1,IQCK,SLC4A8,NCOR2,CSF1,DCAF4,RASSF2,SPOCK3,EFCAB2,DENND2A,SIGLEC8,SYT17,MAPT,MATN3,MN1,NEK1,NF1,NFYA,NPR2,PLXNB1,BCAS3,PTX3,FAT4,NEK11,SLC14A1,ZEB1,GPR161,TPM2,UGT8,WNT7A,ZNF711,MAP3K12,EPM2A" Drug 6575_DN Gly-His-Lys acetate salt; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ADORA1,KIAA1324,APOC1,PPFIA3,CDK10,MADD,BACH1,AP4M1,ABCG1,DCAF8,NR1D2,EPB41L2,F5,PTK2B,ZNF589,USP19,GNG4,MAN1B1,INPP5B,MAP4,NLE1,SLC25A23,PLTP,MAPK3,RAD51D,TRIM68,PEX26,RBM34,KDM4C,EXOC7,PDLIM2,SIN3B,BHLHB9,TMPO,PARD3,CABIN1,ZKSCAN5,PLPPR2,EMSY,SMIM8" Drug 4335_DN Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "APC,SEMA4G,ADAM23,ADGRB2,MYRF,PICK1,CSNK1E,VCAN,DCAF8,HIPK3,ERCC2,CDKL3,FGF1,SEPT9,SRCAP,AHDC1,ATXN2L,TJAP1,INPP5B,ITGA7,ITPKA,KCNN1,LYRM9,NF1,NTRK2,SAMD9,WDR25,LIMS2,SLC9A5,BTBD7,MYH15,KDM4B,CABIN1,TRIO,VIPR2,KLC2,SPHK2,KCNAB1,PHTF2,GAN" Drug 3838_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "AP2A2,AMPH,KCNAB2,APLP1,RASL11B,CAMK2B,SLC16A4,PICK1,CNTFR,CNTN1,PCYT1B,CSF1,MFAP3L,DNM1,DYNC1I1,EDNRB,OLFM1,AFF2,DCTN2,RUNDC3A,GPER1,IFI16,KCNB1,KCNF1,KCNN1,ADAM22,NOVA2,SLC11A2,PLCB2,PNMA3,PKNOX2,ZKSCAN3,RBM34,ARC,TBCEL,WSCD1,PIK3R5,FLRT2,SPHK2,SLC30A3" Drug 1864_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "NDRG2,KCNAB2,APBB2,ARNTL,ZBTB10,SPAG9,IQCK,CREM,PPP1R16B,DAPK1,RCAN1,DTNA,MBNL2,EIF5,ING4,COQ7,AGAP2,ANKFY1,POMT1,BTN2A1,ICA1,TJAP1,LSS,MITF,OCRL,CCSER2,PPP3CC,MAPK3,CCDC88A,BTBD7,TMCC1,KDM4C,IQSEC2,RGL1,ARHGEF9,KIAA1107,SZT2,NSD1,PIK3R5,ZNF32" Drug 6739_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "AGT,APAF1,KCNAB2,GAS7,SLC4A4,SLC2A11,NRP2,SCAPER,CDO1,MFAP3L,SV2B,DTNA,ECM2,HIPK3,ING4,COQ7,ETV1,CORO2B,FGF1,FGFR1,AFF2,DCTN2,GATM,KCNMB4,CNTRL,AP4S1,ELOVL5,IL12A,KITLG,P2RY13,CLDN11,ELOVL2,TMEM231,RGS12,ZFP30,SLC2A5,TBCEL,TMPO,LAT2,PHTF2" Drug 6242_UP Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "AMPH,GAS7,MARK4,SLC4A4,ALDH7A1,CFLAR,SCAPER,CBFA2T2,QKI,ABCG1,RGS6,PDE4DIP,HDAC4,MFAP3L,RCAN1,SUGP2,FER,ALDH1L1,GLYR1,STMN2,SPACA9,TJAP1,INPP5B,MAP4,ADAM22,NTRK2,RETREG1,ZCWPW1,SH3BP2,FRMPD1,SAMSN1,PLCB1,ASTN2,PCDHA5,PLPPR2,VAV1,VGF,WIPF1,SLC17A7,ST7" Drug 4391_DN Sparteine (-) [90-39-1]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ADORA1,BIN1,MARK4,SLC2A11,HAP1,CBFA2T2,B4GALT6,RAB28,SH2B1,EXOG,E2F5,OPTN,ERCC2,FECH,PRKAG2,ANKFY1,SRCAP,INPP1,KPNA5,KITLG,MMP16,ADAM22,CNOT4,RETREG1,LRP12,FNDC3A,PEX26,UNC5B,SPTAN1,SPART,LHPP,ELOVL4,VPS13A,HIRA,PLPPR2,ZBTB14,ZNF24,EMSY,EVI5,HPS4" Drug 2687_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "MTUS1,AMPD3,ATP2B2,AZGP1,RGS11,CABP1,COL9A3,SUSD5,PDE4DIP,CNTNAP2,DZIP3,DGKG,MYEF2,AASS,SRPK3,EPB41,FAM198B,FER,BAIAP2,AGAP2,GCNT2,GFER,HNMT,KCNJ5,MATN2,ADAM22,NEFM,ZSCAN2,RASGRF1,SUGCT,KLHDC8A,ZNF415,ZNF423,SYT5,GPR161,TRIO,TRPS1,MAP3K12,EVI5,JPH3" Drug 4425_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ABHD6,AMPD3,AMT,GAS7,EIF4G3,ALDH7A1,MTMR2,LDLRAD4,CPS1,SIPA1L1,SEC14L5,RASSF2,SPOCK2,EXOG,DNAJB6,ING4,VPS13B,FHL1,TPK1,KIT,KPNA5,ZNF862,PLCD1,MAPK7,C1orf54,SH3BP2,PREX2,FAM214B,CCDC88A,ZHX3,SPTAN1,ZBTB43,CLSTN2,DMXL2,PCDHGA10,HIRA,FLRT2,VIPR2,LAT2,EMSY" Drug 4159_DN "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "NDRG2,APBA2,SYNJ1,SLC25A14,CCNT1,CLGN,SLIT2,TPP1,QKI,CRY2,SNCAIP,FAM169A,DCAF8,DBT,PARD6A,DTNA,APH1A,PLXNC1,DLC1,ZNF589,PRELID3A,KHDRBS3,TXNL4A,GLYR1,GPER1,KHK,ADAM22,NEK1,NF1,NFYA,LRP12,MINDY2,MAPK10,ZDHHC14,SH3BP2,SH3GL3,CDK19,PLCB1,SLC44A1,TMPO" Drug 4602_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.74E-03 1.96E-02 40 194 "ASIC1,MTUS1,TRMT9B,MARK4,SCAPER,TAOK2,QKI,HOMER3,VCAN,SLITRK5,ARHGAP32,DBT,KIAA0753,RCAN1,RRAGB,ST3GAL6,ZNF589,ANKFY1,PDLIM5,ZNF276,HNMT,FAM69A,MBD1,NFYA,PPP5C,PRKAR1B,WDR25,SH3BGR,ABLIM3,PEX26,COA1,SMARCA4,SS18,ARHGEF9,EXOC7,IQCE,FBXW11,HIRA,UPF3A,MAP3K12" Drug ctd:D020122 tert-Butylhydroperoxide CTD 1.31E-04 1.00E+00 1.75E-03 1.97E-02 255 1813 "ABR,ACHE,ABHD6,AS3MT,ACTN1,NDRG3,ADD2,ADORA1,OSBPL1A,AK2,SRPX,AMPD3,AMPH,OGT,PKP4,APAF1,KCNAB2,APOC2,LGR5,CDK10,CASK,ARHGDIA,DYNLL1,ATP2A2,ALDH7A1,DST,SYNJ2,ARHGEF7,FUBP1,GYG2,SGCE,C5,RAB29,CA8,DDR1,CALM1,PTBP2,CAST,CBS,RGN,LRBA,CDC25B,UBE2L6,SOCS6,CNOT8,LHX2,PLAA,CLCN3,TPP1,CLTC,PREPL,C2CD2,AKAP12,NCOR2,CSF1,ARHGEF10,SIPA1L1,VCAN,PDE4DIP,CST3,APPL1,PNPLA8,CTH,DOCK4,TCAF1,ZFYVE16,DAPK1,DBI,HEPH,LYPD1,ZC3H11A,CHRDL1,DMPK,DOCK2,TOM1,DUSP9,MAMLD1,FIS1,EDIL3,TSPAN5,EDN1,EEF1D,SUGP2,EGFR,MBNL2,KMT5B,RASA4,EIF5,PCOLCE2,EPB41L2,LRRC17,ERBB2,ERBB4,GMPR2,CD320,TUBA1B,CHST15,SEC24B,AMOTL2,FHL1,PCYOX1,SYNCRIP,NELFCD,USP21,TRIM16,SARAF,ZNF234,SEPT9,SRRM4,GFER,PPARGC1A,DHRS4,COPS8,RNPS1,GLYR1,FERMT2,LILRB4,PRUNE2,GPER1,GRIN2C,GSN,GSTM5,PSIP1,RNFT2,HAS2,ACOT7,GABARAPL2,HMGCR,HSPA1L,IFI16,IGF1,NKD1,IL6ST,INPP5B,ITGA7,KTN1,STMN1,LIFR,LIMS1,LSS,SMAD1,SMAD9,MAN2A2,MAP4,MARK3,MATN2,MEST,MIA2,MITF,MOV10,MSR1,MT1M,MX1,MYO5A,MYO7A,NACA,NFE2L2,NFIX,SLC11A2,NTRK2,PAX6,PCDH9,OLA1,ABCB1,SERPINI1,PIK3R1,GPSM2,PLCD1,JAKMIP1,SMOX,SMIM7,ING3,POLR2F,PPP3CA,PPP3CC,MAPK3,MAPK9,NDUFS7,CYBC1,PSMA6,PTK2,SPDL1,NKAIN1,PID1,RAP1GDS1,RASGRF1,RBBP8,ZDHHC4,RGS3,NUDT11,RNH1,CCDC25,PCMTD2,RTN1,RXRA,MAPK12,SATB1,SCP2,HES6,SEC14L1,FHOD3,R3HDM2,ANKRD6,SEPHS1,TET1,SMARCC2,RCOR3,IFT122,LIMCH1,PDZD2,KDM3A,SP2,PEG10,SPTAN1,SPTB,SST,ERBIN,KANK1,JMJD6,SYT1,EXOC7,DNMBP,FAM208A,TCEA1,TCF4,USP22,OBSL1,PUM2,SLC35G2,SIRT1,GPR161,TLR4,TMPO,BEX4,PARD3,TP53BP1,TPM2,TRIO,TTC3,TUBB2A,BCL2L13,VSNL1,RICTOR,NDRG4,UPF3A,GDPD5,RNF103,TUBA1A,NAV3,MPPE1,PLSCR4,ST7,HNRNPA3,ACTR3B,MSRB3" Drug CID000520075 vinyl sulfonamide Stitch 1.32E-04 1.00E+00 1.76E-03 1.99E-02 6 9 "EDN1,EDN3,EDNRA,EDNRB,EGFR,ERBB2" Drug CID000451435 AC1L9PN4 Stitch 1.32E-04 1.00E+00 1.76E-03 1.99E-02 6 9 "CALB1,ENO2,MBP,NEFM,NEFH,RET" Drug ctd:D015127 "9,10-Dimethyl-1,2-benzanthracene" CTD 1.32E-04 1.00E+00 1.77E-03 1.99E-02 158 1052 "ACTN1,NDRG2,ADCY5,ADORA2A,HACE1,OSBPL1A,SPARCL1,PPFIA4,APAF1,APOC1,MADD,CASK,RGS20,MARCH3,ASPA,CHRD,MYOM1,KIF1A,MPDZ,BID,CFLAR,IL33,CACNA2D1,CALB1,CAMK2B,CAPN3,KYAT1,SCARB1,SYNGR3,CFL2,FOXN3,ARHGAP22,SLIT2,QKI,HECTD1,CNN3,AKAP6,GDA,PDE4DIP,CST3,GPSM1,ARHGAP32,DBI,AIF1L,LYPD1,KIF19,DNAJB6,EDNRB,EEF1D,EIF4G2,CERCAM,GPHN,TMEM132C,RACK1,FGF13,SYNCRIP,FOXO3,FLNC,ATP13A4,FLT1,PDLIM5,CAMKK2,CGREF1,NSG1,TPPP3,ABLIM2,HIGD1B,GATM,TUBA8,SESN1,MMADHC,GGT7,GHR,PPARGC1A,MALT1,LYVE1,HPGDS,KCNMB4,RAB40B,GPD1,GRB10,GSN,HBA1,HP,IDH3B,IGF1,IL12A,KHK,KIT,STMN1,SMAD1,MAT2A,AQP11,MEIS2,KITLG,MN1,DBNL,HNRNPM,NFE2L2,NFIX,NPTX1,NUCB2,SETD4,OGG1,PDE1C,TMIE,PLCL1,FXYD1,PPP2R2B,PKIA,PRKCB,PTPRD,PPP2R3C,IQSEC3,RDX,SETD5,MAPK12,PUF60,SCAF8,SH3BGR,FBXO11,SLC6A8,SLC12A2,CPEB4,GKAP1,LIMCH1,MYCBP2,SPP1,ITPRID2,MPRIP,VPS13A,PDLIM2,DOCK9,OBSL1,ARHGAP9,DICER1,AKTIP,THRA,TMPO,PARD3,KAT6B,TNS1,PIK3R5,TP53BP2,TPM1,SSBP2,UBE2H,VGF,VLDLR,VSNL1,ZNF32,SH3GLB2,WNK2,RTN4,ACTR3B,FXR1,NETO2,RNF146" Drug ctd:C041786 palm oil CTD 1.34E-04 1.00E+00 1.79E-03 2.02E-02 246 1742 "ACADM,ABHD6,TMCC3,FZD9,AP2A1,MTUS1,PCDH19,SORCS2,AK2,SPARCL1,SRPX,ARHGAP20,LTBP4,AMPD3,MAP4K3,PHYHD1,APOC1,PRX,ARNTL,ARRB2,PLA2G4C,ASPA,ATP1A1,ATP2A2,ATP6V0A1,DOCK11,BCHE,GPR146,PROM1,ARHGEF7,RAB29,CA4,RHBDL1,RUNX1T1,KYAT1,CD38,CDO1,RCBTB2,MS4A7,NGEF,QKI,LY86,CNN3,AKAP6,LETMD1,COL11A2,MAGED1,BAG4,PREPL,CREM,AKAP12,ANKRD44,GDA,CRYM,CSF1R,CSF2RA,CSNK1E,SOCS5,CNTNAP2,CYBB,DOCK4,KATNAL2,ARHGAP24,HDAC4,LONRF1,LIN54,DBI,ARMCX2,SPATA2,HEPH,RHOBTB1,WDR20,DPH1,DRP2,PDCD6IP,ECM2,EDNRB,HIPK3,HEYL,ASB3,EIF4G1,PCOLCE2,ELN,EMX2,COQ7,ADGRV1,GMPR2,NRN1,ABCA8,FCGR1A,FCGR3A,FCGRT,FGF1,FGFR1,FHL1,POLK,SCARA3,SEC23B,FOLR2,SPECC1,KHDRBS3,DOT1L,GAA,GALNT15,IP6K3,HIGD1B,ACSS1,GATM,ALDH1L1,SESN1,PPARGC1A,DHRS4,DBF4,RAB30,GLUL,RAB40B,GPT2,ADGRA3,GSTT2,BVES,PSIP1,GUCY1B1,NCKAP1L,MIER3,HLF,ELOVL5,ACOT7,HMGCR,HNMT,HP,NEGR1,HSPA1L,IRF8,IDH3B,IFI16,MYLK2,ZNF546,IGF1,IL12A,INPP1,ITGAM,ITPKB,SLC35G1,KCNB1,LIFR,SFXN5,GPR155,MATN2,MBP,TM6SF1,MEST,KITLG,DBNL,THYN1,MXI1,MYH3,MYO5A,NBL1,NPR2,NUCB2,OCRL,CHAMP1,PDE4B,CYTL1,PFKFB3,ABCB1,DUSP26,CCSER2,SNX10,SMOX,PLTP,PMP22,PSAT1,SCHIP1,FA2H,SH3KBP1,PPP1R1A,PRKAB2,PRODH,RELN,WBP1L,PTH1R,PTPRE,PTPRG,PTX3,RBBP8,RGS4,RIC8B,ZFHX4,ROBO1,RPE,CLIP1,FNIP1,HES6,TNFRSF19,RASA3,HSPA4L,SGK1,KIF21A,CPEB3,SLC11A1,SLC12A4,NAPB,MTERF2,SLC22A4,SNCA,TMCC1,SPP1,ARHGAP26,CDK19,ST5,ADHFE1,SULF2,CAMTA1,EXOC7,KLHL4,TIAM1,TMEM9,ACTR6,BHLHB9,TLR4,RASD2,TPM1,NPL,WBP2,TUBB2A,UBC,UCHL1,UGT8,VLDLR,LMF1,KLC2,NPDC1,ZIC1,NDRG4,SH3GLB2,ZFAND5,INTS3,GDPD5,HPS4,SEMA3B,KCNAB1,NELFE,PLSCR4,HRASLS,NETO2" Drug 2490_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "NDRG2,ADRB2,MARK4,BCL7A,CFAP410,SLC16A4,RCBTB2,RAB33A,BAG4,CSNK1E,PPP1R16B,ZNF337,KIAA0586,DBT,ZNF804A,RUSC2,DTNA,ING4,NCALD,F5,KAT8,NCKAP1L,HMGCR,LSS,SCAMP5,N6AMT1,ZNF862,NFYA,SLC11A2,PFKFB3,PLCD1,PLEC,MAPK7,CNNM2,RBBP6,SLC2A5,SLC6A8,BTBD7,DDN" Drug 5442_UP Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "C1QTNF1,GAS7,N4BP2L1,ADGRB1,CACNB4,USP2,KCNAB3,GREB1,DCAF4,SPOCK3,DPP6,HIPK3,OPTN,EGFR,MTSS1L,AGAP2,SYT17,LPAR4,GPER1,GRB10,SLC2A6,MAP4,CEP41,PRKAR1B,ZCWPW1,GAL3ST4,RGS4,KLHL11,SALL1,IQSEC2,DDN,ATP10B,MCF2L,ZEB1,TRIM2,SYNE1,ICAM5,SLC30A3,GDPD5" Drug 4310_DN Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "ADAM15,CFLAR,SPAG9,ARHGEF2,SRSF11,FCF1,CGREF1,ERAP1,SRCAP,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,AGFG1,IL6ST,INPP5B,MAP4,NFIX,SLC11A2,CCSER2,NLE1,STRN3,PPP3CA,PTN,SLC25A36,KIRREL1,SEC14L1,ASAP3,CCDC88A,CDK19,ZBTB43,TBL1X,TRIM2,DICER1,TMPO,R3HDM1,ZBTB38,KAT6A" Drug 2729_DN Securinine [5610-40-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "ASIC1,ADRB2,AMT,APBB2,ADAM23,ST3GAL5,OSBPL3,SLITRK5,PPP1R16B,DTNA,TNK2,RASGRP2,FGFR1,PCYOX1,CAMKK2,FYB1,SEPT9,MSL3,RAB40B,IRF8,MAP4,ZNF862,OGG1,GPR85,PLTP,PTCH1,PTX3,SATB1,SEC14L1,SLC2A5,ARHGEF40,TSPYL2,TROVE2,ZC4H2,KANK1,KIAA1107,TRIM9,ZNF74,REEP1" Drug 5565_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "ASPHD1,LTBP4,APBA2,BCAS1,SYNJ2,CA12,HOMER3,RCHY1,LRIG1,GREB1,RCAN1,CNNM1,RASGRP1,EGR3,VPS26C,ZNF589,MSL3,IL6ST,JAK2,KCNF1,KCNH2,MIA2,GIT1,ADAM22,MBOAT7,PPP5C,SAMD9,ZCWPW1,RET,FBXW7,SGK1,SYBU,PREX2,SPTAN1,TMEM121,ZNF34,SEMA3B,ACTR3B,GAN" Drug 5419_UP Methotrexate [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.83E-03 2.06E-02 39 188 "AMPD3,APOC1,MARK4,ADAM23,NRP2,USP2,RCBTB2,VAX2,CNTN1,WHRN,CRY2,DTNA,EGR3,DLC1,FHL1,HPCAL4,FYN,SESN1,GLYR1,RAB30,POLL,NACA,MTRF1L,MAPK10,RASGRF1,RFX2,PNMA8A,ASAP3,OGDHL,SMARCD3,MAPKBP1,RBM34,ARHGAP26,ARHGEF9,KIAA1107,METTL3,UCHL1,KCNK12,ZFP37" Drug CID000002663 celiprolol Stitch 1.40E-04 1.00E+00 1.86E-03 2.10E-02 15 47 "ADRB2,CACNA2D1,TBPL1,CYBB,EDN1,MATK,ABCB1,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,MAPK12,SLC12A4,NETO1" Drug ctd:C483909 torcetrapib CTD 1.43E-04 1.00E+00 1.91E-03 2.15E-02 62 343 "EP400,APBB2,CASK,ATP2A2,DST,LONRF2,HECTD1,AHCTF1,CREM,RBM39,APPL1,CTH,PYGO1,CYBB,TCAF1,GIT2,DBT,EDN1,FSD1L,MBNL2,EIF4G1,AFF2,PDLIM5,HTATSF1,IFI16,IL6ST,MAP4,KITLG,POC1B,MITF,MKLN1,MYO6,AMZ2P1,NFE2L2,PDE4B,PDE4D,ZNF655,CCSER2,LRP12,ING3,PRKACB,VPS13C,RBBP6,EXD2,ZNF331,CSRNP3,MRAS,CHD9,CCDC88A,CPEB4,ERC1,ITPRID2,PRRC2C,TACC1,TCF4,TRIM2,PMS2CL,TP53BP1,TTC3,FLRT2,SLC30A4,ZNF37BP" Drug 7503_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.44E-04 1.00E+00 1.92E-03 2.16E-02 38 182 "ADRB2,MARK4,ADGRB2,ST3GAL5,BAIAP3,HIP1R,USP2,STOML1,ABCG1,PDE4DIP,CNTNAP2,BAIAP2,PDLIM5,CYP46A1,SLC2A6,ITGA7,LSS,MAPT,TAGLN3,PCDH9,SERPINI1,PRPH,KCTD17,RPS6KA2,FAM102A,ASAP3,ARFGAP1,KDM4B,ARHGAP26,SPTAN1,THSD1,ELOVL4,CEP68,RGL1,ARC,SYT1,SMG6,R3HDM1" Drug 1661_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.44E-04 1.00E+00 1.92E-03 2.16E-02 38 182 "C1QTNF3,CDC42BPA,MARK4,CFLAR,FOXN3,ENTPD4,SH2B1,CSNK1E,PDE4DIP,CTH,TOM1,CELSR3,ING4,INPP5K,BRD8,ZNF276,RAB40B,STON1,ICA1,ADAM22,NEK1,PDPK1,MINDY2,PTCH1,RGS3,CARF,PCMTD2,NEK11,TCP11L1,KDM3A,IQSEC2,CEP68,PLCB1,TRIM2,PCDHA6,BEX4,UBE2H,SPHK2" Drug 4989_UP Thioguanosine [85-31-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.44E-04 1.00E+00 1.92E-03 2.16E-02 38 182 "BIN1,EPB41L5,N4BP2L1,BAIAP3,RUNX1T1,SRSF11,EDNRB,ELN,NRN1,CORO2B,AMOTL2,FHL1,OGA,SRCAP,GFER,LYVE1,FICD,ICA1,KCNH2,MEF2C,MIA2,NACA,NOVA2,MTRF1L,PNMA3,EMID1,PPM1E,RBM34,SP2,ZC3H13,ATP10B,THSD1,WSCD1,DICER1,TRIO,VLDLR,ZNF711,EMSY" Drug CID000003733 AC1MU1S9 Stitch 1.45E-04 1.00E+00 1.92E-03 2.16E-02 94 572 "ADCY5,ADCY6,ADCY8,ADORA2A,AGT,MYH7B,PHF12,ATP2A2,ATP2B2,CACNA2D1,CALM1,CAMK2B,CAST,CCK,KRIT1,CD86,LRBA,NUMBL,CHN2,MYL6B,CNR1,NRG2,CREM,PLCXD3,CYBB,B3GAT3,EDN1,IRAK4,IGSF6,PTK2B,FCGR3A,NELFCD,CAMKK2,ATP2C1,FYN,IQGAP2,ERAP1,BRD8,KCNMB4,PLCD4,GUCY1A1,GUCY1B1,IRAK3,TNFAIP8L3,MYLK2,IL12A,ITGAM,KCNN1,KCNN3,ASPRV1,MBP,MEF2C,SCAMP5,NCF2,NPR2,OXTR,P2RX7,TREM2,PDE1C,PIK3C2A,PIK3R1,PLCB2,PLCD1,LRP12,PPP3CA,PPP3CC,PRKACB,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTH1R,PTK2,RASGRF1,RASGRF2,SATB1,SGK1,SNAP25,PEG10,NFASC,PLCB1,SYN2,SYT1,ACTR6,CABIN1,PIK3R5,TRPM2,VGF,VSNL1,PLD4,NETO1" Drug 4428_DN "aspirin, USP; Down 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "APBB2,MPDZ,BMPR1B,MTMR3,QKI,CREM,AATK,CSNK1E,VCAN,PDE4DIP,SLITRK5,ARHGAP24,EDIL3,HIPK3,FEM1B,CNNM1,IRAK4,ING4,NCALD,EZH1,SYT17,CNTRL,RASSF8,ATXN2L,ICA1,KITLG,MT1M,NF1,NPR2,PLCB2,KCTD17,CCDC88A,COA1,SPTB,IQSEC2,ZEB1,TSN,XRCC4,EPM2A,PHTF2" Drug 4972_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "NDRG2,AK2,APBA2,GAS7,HIP1R,SLC16A4,CLGN,SRSF11,HOMER3,ARHGEF10,RASSF2,TBC1D5,MAML1,PARD6A,DTNA,EGR3,FGFR1,SRCAP,USP19,TXNL4A,GPER1,NXPH3,LSS,RETREG1,NLE1,ZNF493,RET,RGS12,RPS6KA2,SGK1,FAM214B,ZBTB43,PLCB1,ANKRD12,TBCEL,PARD3,CABIN1,WIPF1,LAT2,SEMA3B" Drug 4015_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADCY6,PKP4,BCAS1,PPFIA3,ADAM23,CFAP410,ARHGAP33,VAX2,CNTFR,AKAP7,CTH,HDAC9,MYEF2,FGFR1,DCTN2,OGA,ERAP1,NEU3,IL6ST,SMAD1,MSR1,NPTX1,PDE4D,PRPH,PTPRN2,BEND5,RFX3,PNMA8A,MRAS,SNCA,SPTAN1,TPM1,CHST5,TRIO,VGF,VIPR2,LAT2,MAP3K12,DPF3,JPH3" Drug 4366_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "NDRG2,C1QTNF1,KCNAB2,SYNJ2,CDH2,TAOK2,TPP1,CNTN1,SPOCK3,EDNRB,EGFR,PLXNC1,ST3GAL6,DISC1,MSL3,GNAO1,GNG4,RASSF8,IFI16,KCNH2,MATN3,MYCN,NPY,PCSK1,PGAM2,CEP41,RASGRF1,KHDRBS2,GAL3ST4,RFX2,ZC3H13,CDK19,SYP,TCF4,TRO,HIRA,FLRT2,WIPF1,LAT2,SLC17A7" Drug 3671_DN Mebendazole [31431-39-7]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "APBB2,SEMA4G,CDK13,SCAPER,SCARB1,RAB28,CNTFR,SH2B1,DZIP3,GPRASP1,DCAF8,MBNL2,MRNIP,VPS26C,RRAGB,SCML2,BAIAP2,DISC1,SESN1,GLYR1,MAP4K5,MUM1,KHK,SLC25A23,FAM184A,ZNF821,ASAP3,CCDC88A,RCOR3,IFT122,SPATA7,LHPP,SAMSN1,SS18,PHLDB1,TCF4,TNS1,WNT7A,ZNF74,SMIM8" Drug 6756_DN Lynestrenol [52-76-6]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASIC1,ARRB2,STX16,SYNJ2,LDLRAD4,NRXN3,QKI,AKAP7,CPS1,ENTPD4,PDE4DIP,DCAF8,RUSC2,CDON,IRAK4,ETV1,ZNF589,FYB1,ZNF44,GAD1,GPD2,LPAR4,IL6ST,MGAT3,MYT1,PLCD1,PLXNB1,MINDY2,GRAMD1C,AMBRA1,PPP4R3A,ARHGAP26,SS18,KIAA1107,ZEB1,RPGRIP1L,BEX4,WIPF1,EVI5,PHTF2" Drug 2776_UP Aconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADORA1,SYT13,KCNAB2,DDO,APOC1,PPFIA3,PPP4R4,SLC16A4,CHN2,AKAP5,SPOCK2,DNAH9,DYNC1I1,SLC12A6,PLXNC1,SPEG,DLC1,DISC1,PCDH17,TDRKH,IL6R,LAMA2,MAN2A2,NF1,CLDN11,PLCB2,MINDY2,CEP41,CCDC40,RNASE1,ARHGEF40,SPTB,CLSTN2,SSTR2,CRTC1,CHST8,TK2,HIRA,FAM155A,DNALI1" Drug 2313_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADRA1D,AP2A2,BIN1,SEMA7A,APOC1,CDK13,SLC2A11,ALDH7A1,CA4,RCBTB2,ASIC3,RAB33A,CSF1,PDE4DIP,LYPD1,CELSR3,SEPT9,INPP5K,MSL3,ICA1,TJAP1,KCNN1,MAP4,MIA2,NF1,PCDH9,PLCD1,STRN3,LRP12,MBOAT7,ELOVL2,CEP97,TRIM68,TCP11L1,EMID1,BTBD7,TROVE2,AP4E1,PLPPR2,MAP3K12" Drug 7237_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "FZD9,ADORA1,NME5,AK2,GAS7,MARK4,KSR1,CALB1,USP2,SOCS6,ARMC8,CRY2,ARHGEF4,GIT2,EXOG,MBNL2,TNK2,DLC1,KAT8,ZNF589,KHDRBS3,OGA,FYB1,TDRKH,JAK2,KIF2A,LIG4,KITLG,MMP16,NF1,PPP1R1A,GRAMD1C,ZSCAN32,RASGRF1,CCDC88A,PLCB1,TCF4,HIRA,UBE3A,SPHK2" Drug 3522_UP Imidurea [39236-46-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASIC1,NME5,ATP2B2,RGS11,SYNJ1,CFAP410,HAP1,ARHGEF2,CLTB,CNN3,AKAP7,AKAP6,CPS1,NCOR2,PHF14,SEC14L5,KLHL3,DMPK,ELN,HSD17B14,MTSS1L,ERCC2,TJAP1,IL6R,KCNH2,MPP2,TAGLN3,SMOX,LRRN3,MAPK7,SAMD9,CCDC40,CPEB3,ST6GAL1,PLCB1,PCDHGA10,DOCK9,SLC35G2,ZFP37,SLC17A7" Drug 4653_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADCY6,CDK10,ARNTL,CDK13,MTMR2,SPAG9,ARHGEF1,SCARB1,ZMYM4,TPP1,QKI,PDE4DIP,GIT2,DBT,EXOG,FCF1,EGFR,ETV1,ANKFY1,PDLIM5,ZNF276,HSF2,TJAP1,FAM69A,NDP,NFYA,STRN3,FUZ,SHMT2,SLC22A4,ZKSCAN3,SS18,NXT2,BHLHB9,SSBP2,HIRA,WIPF1,ZNF711,EVI5,PHTF2" Drug 898_DN 5213008; Down 200; 18uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ACTN1,APLP1,SYNJ2,MTMR3,CBR1,CLTB,CSNK1E,SOCS5,HDAC4,SEZ6L2,EGR3,CDKL3,FGFR1,PDLIM5,INPP5K,BTN2A1,JAK2,MEIS1,SLC11A2,PALM,PMP22,PRKAR1B,RIPOR1,ZCWPW1,TCP11L1,RPS6KA2,MAP6D1,ZFP30,EPN2,TROVE2,CEP68,TRIM2,TNS2,THRA,TIAM1,CABIN1,TPM1,WBP2,GDPD5,TIGD6" Drug 6834_UP Pindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADORA1,NME5,BEGAIN,KCNAB2,SEMA4G,PPP4R4,CFLAR,FUBP1,BAIAP3,CALB2,HIP1R,USP2,ARHGEF1,CLGN,AKAP6,DBN1,DTNA,FAM13A,FGFR3,SPACA9,HNMT,AFDN,MPP2,ADAM22,NF1,PDE1C,PGAM2,ZSCAN2,SLC11A1,ZHX3,THSD1,R3HDM1,CABIN1,TRPM2,FLRT2,VLDLR,PRDM10,SLC17A7,KCNAB1,ITM2C" Drug 4313_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "LTBP4,FAM135A,ANK2,APAF1,ASPA,PTCH2,SLC4A4,SYNJ2,MTMR3,BAIAP3,CALB2,NCOR2,CNTNAP2,CYBB,RIPOR2,MAML1,BRINP1,MFAP3L,DTNA,EGFR,BAIAP2,DCTN2,EFCAB2,GPER1,GRIK5,PACRG,NF1,NPTX2,OPRL1,CDK18,ACSS3,RFX2,PKNOX2,SLC11A1,SPP1,RBM26,ATP10B,TROVE2,CRTC1,LAT2" Drug 6379_UP PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADRA1D,C1QTNF3,APAF1,APBB2,ARRB1,DNAH17,ALDH7A1,ATP6V0A1,ADGRB2,CACNA2D1,CBS,NRXN3,STOML1,FAM149A,NCOR2,CYBB,HS3ST2,DTNB,CELSR3,EGFR,PIPOX,DLC1,EFCAB2,OGA,GABRB3,LILRA2,MATK,MMP16,NTRK2,RGS4,TCP11L1,SLC9A5,ZHX3,SZT2,DICER1,GPR161,TNS1,TPM2,ZNF74,MAP3K12" Drug 6795_DN Mebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASPHD1,ABHD6,ALCAM,PPFIA3,SLC4A4,KIF1A,CBFA2T2,SRSF11,RCHY1,AKAP12,ARHGEF10,PDE4DIP,ARHGAP32,KIAA0586,HIPK3,IRAK4,ING4,ANKMY1,FHL1,GRB10,MAP4,MIA2,MPP2,NNAT,CNOT4,SLC11A2,RETREG1,PMP22,PRODH,CEP97,SH3BP2,ANKRD6,LIMCH1,MAPKBP1,ARHGAP26,NXT2,TFIP11,SEMA3B,FIP1L1,UBE3B" Drug 6510_DN Scopoletin [92-61-5]; Down 200; 20.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASPHD1,APLP1,CFLAR,BMP7,PLAA,LRIG1,SIPA1L1,FAM169A,DCAF8,DAPK3,C2CD2L,LYPD1,EGFR,KAT8,FGFR1,BAIAP2,INPP5K,GNG4,STON1,GRIK5,IL6R,MAP4,MEIS1,NF1,OGG1,MINDY2,RIPOR1,CEP97,RGS12,RNASEL,AMBRA1,PEX26,FAM214B,PKNOX2,LIMCH1,KANK1,TACC1,ZNF24,EMSY,ST7" Drug 2515_DN Hexestrol [84-16-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "MAP4K3,APBB2,NCOA1,ADAM23,CD86,TPP1,QKI,RCHY1,BAG4,SLITRK5,DBT,RCAN1,DTNA,FAM13A,ENO2,MTSS1L,ST3GAL6,ZNF589,CSPG5,GAA,INPP5K,LILRA2,LPAR4,GRM8,TJAP1,JAK2,MAP4,MYT1,ZCWPW1,GSTCD,SLC6A8,CCDC88A,SNCA,TMCC1,KDM4C,TMPO,TNS1,FLRT2,VIPR2,LAMP5" Drug 3124_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ABHD6,BRAP,MARK4,BACH1,CAMK2G,SCARB1,CSF1,CSNK1E,TM9SF4,RUSC2,C2CD2L,RHOBTB1,EIF4G2,COQ7,CINP,CGREF1,SEPT9,RAB40B,PCLO,MAP4,MEF2C,NINJ2,PDE4D,PLCD1,PLEC,SLC25A23,MARCH1,ZC3H14,SS18,JMJD6,EXOC7,PDLIM2,KIAA1107,TCF4,SYNE1,NPDC1,ATP6V0E2,SPHK2,REEP1,MAP3K12" Drug 4192_DN Roxithromycin [80214-83-1]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "MTUS1,TRMT9B,CDK13,ST3GAL5,C5,ARHGAP22,PLAA,LY86,AATK,RGS6,ARHGEF4,DBT,EXOG,ETV1,RRAGB,F5,ANKFY1,OGA,KCNMB4,GRM8,GUCY1B1,MUM1,INPP5B,ZDHHC14,RGS4,MAPK12,CSRNP3,MRAS,FBXO11,PPP4R3A,DDN,SS18,DNAH7,THRA,TIAM1,SSBP2,VGF,WIPF1,XRCC4,KCNAB1" Drug 3862_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "KCNAB2,APOC1,SEMA4G,ADAM15,CACNA1I,USP2,SLC16A4,TPP1,SULT4A1,CNTFR,AKAP6,SNCAIP,CSF1R,CNTNAP2,FAM169A,SNPH,DAPK3,ING4,ERCC2,CAMKK2,GLYR1,HTATSF1,GPER1,GSN,IL6ST,LSS,TM6SF1,KITLG,ADAM22,GAL3ST4,SEMA6D,CPEB3,ST6GAL1,ZBTB43,ARC,TBCEL,SLC44A1,TRIO,NLRP3,RNF146" Drug 5056_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASPHD1,APAF1,SEMA4G,PRX,SLC4A4,FUBP1,CACNA1G,LDLRAD4,SYNGR3,PICK1,IQCK,WHRN,CABP1,RGS6,DBT,DUSP9,PLXNC1,MTSS1L,FGF1,GFER,GNG4,LPAR4,TPPP,LIFR,LSS,MAPT,NTRK3,OPRL1,DCHS2,PTPRH,PID1,TCP11L1,ASAP3,SLA,SLC4A3,ZBTB43,DDN,PHLDB1,SLC44A1,CHST5" Drug 4581_DN Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "KCNAB2,CACNA1A,ARHGEF1,ARHGAP33,TAOK2,PICK1,HINFP,ARMCX2,EXOG,EDNRA,FAM13A,RGS17,RRAGB,FGFR1,CINP,PDLIM5,FYB1,STON1,MAP4,MMP16,LYRM9,NDP,GAL3ST4,ZNF671,ZNF821,AMBRA1,FBXO11,ANKRD6,PEX26,ARHGEF40,ARHGAP26,ASTN2,DOCK9,TNS1,SSBP2,VGF,VIPR2,LAT2,XRCC4,KCNAB1" Drug 4117_UP Etifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "GAS7,APOC1,RASL11B,SYNJ2,CBFA2T2,RCBTB2,LHX2,LY86,AKAP7,FAM149A,WHRN,DAPK3,SV2B,TMCC2,SNX29,PLXNC1,EPHB1,OLFM1,DCTN2,CINP,HLF,ICA1,MIA2,MSI1,ADAM22,PCDH9,PPP5C,PRKAR1B,ENOX1,GSTCD,TCP11L1,SH3BP2,FAM214B,MAPKBP1,SNCA,KDM4B,KDM4C,KIAA1107,THRA,KCNAB1" Drug 3423_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ABR,SEMA7A,APAF1,APBB2,APC,APOC1,CDC14B,ARHGDIG,CAMK2B,FOXN3,TPP1,CNTNAP2,DCAF4,DMPK,DTNA,OPTN,ELN,SCML2,ZNF589,FHL1,GAD1,GALC,KCNN1,MEF2C,MIA2,CNOT4,NPR2,CEP41,PRKAR1B,ZDHHC14,RGS12,ZKSCAN3,CDK19,IQCE,PCDHA6,PARD3,TNS1,LMF1,ITM2C,PHTF2" Drug 3826_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADGRF5,SLC4A4,BMP7,LARGE1,HOMER3,PICK1,AKAP5,ABI3BP,SH2B1,DCAF4,DAPK3,MFAP3L,DUSP9,CELSR3,SUGP2,CINP,PRELID3A,GPR75,GRIK5,CACFD1,HAS2,ATXN2L,ITGA7,KIFC3,TM6SF1,NTRK2,RETREG1,RGS4,RXRA,RASA3,NLGN1,FAM214B,ZNF334,RBM34,DOK5,LHPP,ARC,GPR161,TK2,PARP11" Drug 4182_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "APOC1,AQP6,SLC2A11,CACNA1I,CBFA2T2,WHRN,CSF1,CNTNAP2,HDAC9,DAPK1,DMD,DMPK,FAM13A,DCTN2,DLL3,OGA,GCNT2,SRCAP,PCDH17,SOX21,HLF,CNOT4,DCHS2,SNRK,GAL3ST4,SALL1,SCN8A,AMBRA1,PKNOX2,ZNF334,LIMCH1,LMO3,SZT2,SLC35G2,TEK,SLC44A1,TNS1,OSBP2,WIPF1,ADAMTSL3" Drug 3530_DN (-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASPHD1,BIN1,AMT,KCNAB2,RASL11B,CFLAR,SOCS6,SULT4A1,WHRN,ABI3BP,NECTIN3,CRY2,CSNK1E,RUSC2,RCAN1,SUGP2,NCALD,SPACA9,MAP4,MAPT,ADAM22,NF1,NNAT,SLC11A2,MBOAT7,PPARA,PRODH,EMID1,SEMA6D,STX1A,VPS13A,CHST8,ZNF34,SLC44A1,CABIN1,ZKSCAN5,VLDLR,SPHK2,ST7,KAT6A" Drug 4495_DN (-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ACTN1,ADRB2,APC,CDK10,KIF1A,ADGRB2,SCAPER,CRY2,AATK,SNPH,ARHGAP24,FGF1,CSPG5,GAD1,DISC1,RNFT2,KCNJ5,MAPT,MEF2C,MT1M,LYRM9,WDR25,RIPOR1,FAT4,ROGDI,SUGCT,ATXN2,FAM102A,ASAP3,BTBD7,KDM4B,IQSEC2,COBL,EXOC7,TNS1,WNT7A,NPDC1,XRCC4,ZNF74,NAV3" Drug 2973_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "MTUS1,CASK,ARRB1,CDK13,CD86,HOMER3,MAGED1,CSF1,SIPA1L1,VCAN,PDE4DIP,ZNF337,TM9SF4,SPATA2,FAM13A,FGFR1,FLT1,ERAP1,SEPT9,SRCAP,SLC2A6,MAP4,MX1,CNOT4,PDE4D,ENPP2,PTPRN2,FAM184A,RASA3,DZIP1,SLC2A5,FAM214B,DOP1A,SPP1,UNC5B,TSPYL2,ITPRID2,ZEB1,FLRT2,NT5M" Drug 7172_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "BRAP,AK2,CDK13,CREM,PPP6R2,FEM1B,TNK2,VPS26C,FYN,GALC,RNFT2,MUM1,AGBL5,NEK1,CNOT4,PLEC,SLC25A23,RGS3,FBXW7,AMBRA1,PDZRN3,KDM4B,SOX3,SPATA7,ZHX3,ZSWIM8,SS18,CEP68,TACC1,SIN3B,SATB2,CABIN1,TP53BP1,SSBP2,ZKSCAN5,PLPPR2,VGF,LMF1,REEP1,MAP3K12" Drug 2478_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "NDRG3,APAF1,CDK10,NCOA1,STX16,CFLAR,MYRF,CD86,SOCS6,CNOT8,PLAA,IQCK,SH2B1,CRY2,DOCK4,DBT,ERCC2,SCML2,ZNF589,FGFR1,TJAP1,JAK2,ZNF862,CNOT4,NLE1,PTPRN2,SEC14L1,MRAS,SH3BP2,FBXO11,EPN2,IZUMO4,SPART,ADGRL3,TCF4,ZEB1,SMUG1,LMF1,ZNF24,UPF3A" Drug 449_UP radicicol; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Up 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ASIC1,MTUS1,AK2,APBB2,STX16,CNTN1,HINFP,CSF1,SIPA1L1,SOCS5,CTH,ARHGAP32,GAPVD1,FBXL5,DNAJB6,E2F5,EGFR,TNK2,F5,PCYOX1,ARFIP1,KTN1,LAMP2,AFF1,OXTR,SERPINI1,MAPK3,ZSCAN32,PTPRN2,C1orf109,HSPA4L,LIMCH1,PDZD2,ZC3H13,TSPYL2,EXOC7,TBL1X,BHLHB9,BEX4,JMJD1C" Drug 4249_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ADRA1D,TRMT9B,APBB2,APC,APOC1,SEMA4G,MARK4,ADGRB2,NRG2,VCAN,DTNA,TOM1,EDN1,MBNL2,ANKMY1,ST3GAL6,CGREF1,ZNF44,RUNDC3A,GPR75,POLL,LSS,MATN3,AFF1,OGG1,PTPRN2,ZCWPW1,SBF1,FRMPD1,KANSL3,RBM26,CEP68,SYT1,THRA,TIAM1,TSC2,OSBP2,CLIP2,EVI5,SEMA3B" Drug 5460_DN Acemetacin [53164-05-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "ABR,ADCY6,NME5,APBB2,PPFIA3,CDC14B,ARHGDIG,KIF1A,CBFA2T2,CLGN,ABI3BP,CSNK1E,SIPA1L1,CNTNAP2,DOCK4,RUSC2,MED12,DTNA,PLXNC1,KAT8,FHL1,ANKFY1,GRIK5,IL6ST,MAP4,ADAM22,MAPK7,ELOVL2,RIPOR1,ZDHHC14,ASAP3,SLC6A8,MAPKBP1,TTBK2,PLCB1,PCDHA6,SLC44A1,PARD3,MPPE1,SENP7" Drug 3807_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-04 1.00E+00 1.92E-03 2.16E-02 40 195 "AMT,APC,SEMA4G,IL33,RAB26,WHRN,AKAP5,NRG2,HAPLN1,CSF1,DZIP3,TBC1D5,SPOCK3,CNNM1,FAM13A,OGA,ERAP1,ATXN2L,SHISAL1,JAK2,KIFC3,MAPT,NDP,NF1,PLXNB1,SNRK,FAT4,FAM184A,ATXN2,EPN2,LIMS2,ZNF334,LIMCH1,KDM4C,WSCD1,TCF4,TIAM1,CBX5,TNS1,REEP1" Drug CID000439587 polyproline Stitch 1.46E-04 1.00E+00 1.92E-03 2.16E-02 55 295 "MTUS1,BIN1,APBB2,ATP1B3,RIPK1,ADAM15,RGS9,CD86,CFL2,NGEF,CNR1,WHRN,AKAP5,TRIM69,ARHGEF4,USP6NL,ELMO1,RUSC2,DYNC1I1,EGFR,TENM1,TNK2,ELN,PPP1R1B,EVL,PDLIM5,FYN,AHDC1,TXNL4A,TCERG1,PACSIN2,RBPJ,MATK,MYO5A,NCF2,NPY,TREM2,PLEC,SH3KBP1,RASGRF2,YY1AP1,SNX22,PTGR2,S100B,FOXRED1,SH3BP2,SH3GL3,SLA,FNBP1,ACTR6,TP53BP2,WBP2,WIPF1,SLC17A7,JPH3" Drug CID000000762 GTP - Na Stitch 1.54E-04 1.00E+00 2.03E-03 2.28E-02 141 925 "ABR,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADRA1B,ADRB2,AP2A1,AP2A2,NME5,ARHGAP20,DOC2A,AMPD2,AMPD3,AMT,ARHGDIA,ARRB1,SEC11C,RGS9,AP1M1,CACNA2D1,CALM1,KRIT1,CCNH,CCNT1,RGN,P2RX6,ARHGEF1,COPB2,CHN1,CHN2,ARHGAP22,CLTC,NGEF,MAP4K4,AKAP5,SEC24C,CSNK1E,CSNK1G3,GPSM1,HDAC9,ARHGAP32,ARHGAP24,RHOBTB1,DMD,DNM1,SLC25A18,DNM1L,EEF1D,KLHL5,FAM13A,EGFR,RASA4,EIF4G1,EIF5,TUBD1,RASGRP2,ERCC2,RRAGB,TUBA1B,PTK2B,TUBB3,SEC24B,POLR1B,SCARA3,AGAP2,NELFCD,RASL10A,CAMKK2,IQGAP2,TUBA8,RAB40B,GNAL,GNAO1,GNG4,MCHR1,GUCY1A1,GUCY1B1,ARHGAP36,MSL1,KITLG,MX1,MYO5A,NCF2,NF1,NME4,NPY,NPR2,OCRL,GNG2,PKM,GPSM2,POLG,POLR2F,PRKCB,MAPK3,KLK6,PTK2,QDPR,RASGRF1,RASGRF2,RNASE1,RPL15,RPS20,MRAS,COPZ1,SIRT2,ARFGAP1,ARHGAP26,SST,SSTR1,SSTR2,SUPT5H,ARHGEF9,PLCB1,TAF6,MLST8,TAF9,TBL1X,TCEA1,ARHGAP9,DICER1,TIAM1,TRIO,TSC1,TSC2,TUBB2A,TUBB1,UBC,UBTF,VAV1,VIPR2,XPO1,POLR3H,PRTFDC1,TUBA1A,NELFE,RTN4,AAAS" Drug 1212_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.58E-04 1.00E+00 2.08E-03 2.34E-02 36 170 "ABHD6,ADRB2,ARNTL,MARK4,ST3GAL5,CHN2,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,MRNIP,RGS17,TAOK3,BAIAP2,FYN,GUCY1B1,FAM69A,MMP16,TAGLN3,PCDH9,SERPINI1,RETREG1,PTCH1,RGS4,FBXW7,SH3GL3,SYBU,BTBD7,KDM4B,ELOVL4,RGL1,SYT1,TACC1,RPGRIP1L,UBE2H" Drug CID000004497 nimodipine Stitch 1.62E-04 1.00E+00 2.09E-03 2.35E-02 32 145 "ACHE,BRAP,APLP1,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CACNA2D2,ABCG2,APPL1,EDN1,EDN3,PTK2B,ZMYND10,ATP2C1,GABRG1,GABRG2,GRIN2C,GRIN2D,GRM2,GRM8,ABCB1,PKD1,QDPR,RYR3,CASC3,TPCN2" Drug CID000077802 3-chlorobenzylamine Stitch 1.62E-04 1.00E+00 2.09E-03 2.35E-02 23 91 "SYT13,DOC2A,C5,CACNA1B,RIMS2,SHANK1,RASA4,SYNCRIP,SYT3,GPR37,SYTL4,PACRG,NCF2,RBBP8,RGS4,RASA3,SNAP25,SPP1,ERC1,SS18,STX1A,SYT1,SYT5" Drug 6166_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.62E-04 1.00E+00 2.09E-03 2.35E-02 38 183 "PDE8B,SLC4A4,FAM189A2,CREM,PDE4DIP,JAKMIP2,FAM13A,MBNL2,SPEG,FGFR1,BAIAP2,AGAP2,OGA,GRIK5,MSR1,NF1,NINJ2,NNAT,NTRK2,NTRK3,PDE4B,PFKFB2,CCSER2,PMP22,MBOAT7,PRKACB,GALNT10,HSPA4L,ZC3H13,ATP10B,PHLDB1,PLCB1,WSCD1,TPM1,CLIP2,ZBTB38,PRDM10,FAM13C" Drug 3480_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.62E-04 1.00E+00 2.09E-03 2.35E-02 38 183 "C1QTNF3,LTBP4,AMT,APAF1,GAS7,ARHGDIG,SYNJ1,CBFA2T2,ARHGEF2,RCBTB2,SRSF11,AKAP7,MAML1,SEZ6L2,MBNL2,ARMCX1,BAIAP2,PDLIM5,STON1,GPER1,HMGCR,INPP5B,LSS,MMP16,ADAM22,ZNF862,PCDH9,MAPK7,C1orf54,CARF,ROBO1,PREX2,UHRF1BP1L,PLCB1,TRIM2,PCDHA6,VLDLR,EVI5" Drug 1590_UP Betamethasone [378-44-9]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.62E-04 1.00E+00 2.09E-03 2.35E-02 38 183 "ADD2,AMT,APC,ARNTL,CA12,RCBTB2,AKAP7,PPP1R16B,FEM1B,FAM13A,EPB41L2,DENND4A,VPS26C,CRCP,GLUL,IRAK3,MAN1B1,ITGA7,KCNH2,AFF1,MPP2,NTRK2,PLCD1,RETREG2,RDX,ATXN7,FNDC3A,SLA,SLC11A1,ELMO2,KDM4B,POGZ,SAMSN1,STAU1,KANK1,FLRT2,VIPR2,WIPF1" Drug 6039_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "SYN3,C1QTNF1,AMPH,BIN1,GAS7,SLC4A4,CACNA1I,CDH2,HOMER3,CNN3,PICK1,ABI3BP,SPOCK3,EGR3,EIF1,KHDRBS3,FYB1,GPR162,ADAM28,PCDH17,RUNDC3A,CACFD1,ATXN2L,KCNN1,MBP,ADAM22,NEFH,NOVA2,PALM,NECAB2,LRRN3,MASP1,PTPRB,RGS12,SCN2B,SNAP25,SNCA,UNC5B,LAT2,JPH3" Drug 5255_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "SEMA6A,APBA2,FAM131A,CRMP1,PDE4DIP,GREB1,DGKG,RUSC2,DMPK,EDN3,EGR3,EIF4G2,F5,FGFR1,ERAP1,GRIK5,HLF,JAK2,KCNN2,LIFR,MID1,MMP16,ADAM22,TAGLN3,MX1,NF1,PCBP3,TREM2,TMOD2,LRP12,SCN7A,PEX26,PKNOX2,HECW1,PEG10,CDK19,EXOC7,DMXL2,DNALI1,SEMA3B" Drug 4833_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,BIN1,APBB2,MARK4,CA4,WHRN,SH2B1,CNTNAP2,GIT2,MFAP3L,SGSM2,EDNRA,COQ7,MTSS1L,ERCC2,FGFR1,FAM49B,TPK1,KHDRBS3,ERAP1,POLL,GPER1,PCLO,ELOVL5,INPP5B,NCAM2,NTRK2,PPARA,PPP2R2B,EPN2,BTBD7,SNCA,UHRF1BP1L,TRIM2,SZT2,TPM1,XRCC4,SPHK2,KCNAB1,EPM2A" Drug 6988_DN clozapine; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "OSBPL1A,CDC42BPA,PPFIA3,SCARB1,SRSF11,SOCS6,RAB28,HINFP,ZNF337,GIT2,DNM1,FGFR3,FYN,TXNL4A,GPR37,MEIS2,MITF,NRCAM,OXTR,CCSER2,PRKAR1B,PRODH,CNNM2,TMEM260,RAD51D,SH3BP2,FERMT1,FNDC3A,BTBD7,CDK5RAP2,ZBTB43,EXOC7,TBL1X,SATB2,TRIM2,CLASP1,UBE2H,VAV1,NDRG4,EPM2A" Drug 1912_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AMT,PPFIA3,RUNX1T1,CDH2,B3GAT3,RUSC2,DTNA,EDN1,EPB41L2,SCARA3,PDLIM5,SRCAP,GDF9,AHDC1,HTATSF1,MUM1,IL6ST,KIFC3,MYO9A,ZNF426,PRKACB,RIPOR1,NEK11,FAM192A,SBF1,ATXN2,ZNF821,WDR47,ARHGEF40,SMARCD3,ZHX3,LHPP,SS18,NXT2,TACC1,TK2,TSC2,UBE3A,TFIP11,GDPD5" Drug 3999_UP Gramine [87-52-5]; Up 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,APBB2,APOC1,AZGP1,MPDZ,NRP2,BAIAP3,NRXN3,AKAP5,CSF1,DZIP3,SGSM2,TENM1,DLC1,FGF1,FLT1,FYB1,SIGLEC8,NEU3,IL6ST,MATN3,AFDN,RETREG1,PPP5C,MASP1,GAL3ST4,GSTCD,RTN1,MRAS,KIF13A,SSTR2,SYT5,EXOC7,TAL1,SLC44A1,R3HDM1,VGF,VIPR2,DPF3,JPH3" Drug 7430_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AP2A2,ALCAM,APOC1,BCAS1,CDK10,QKI,AKAP7,PDE4DIP,RUBCN,GPRASP1,DCAF8,KIAA0586,PARD6A,DTNA,FYN,MSL3,NLE1,SLC25A23,FA2H,PRKAR1B,PTPN13,TMEM231,GTDC1,FERMT1,ANKRD6,PEX26,SLC6A8,UHRF1BP1L,LHPP,POGZ,COBL,ANKRD12,MCF2L,PDLIM2,PCDHA6,CABIN1,MPPE1,ST7,KAT6A,GAN" Drug 7167_UP Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,ADGRF5,DOC2A,APOC1,MARK4,RGS11,NRP2,CACNB4,QKI,AKAP12,NCOR1,SOCS5,PDE4DIP,PPP6R2,DAPK3,LYPD1,EGR3,AASS,ING4,SEMA4D,FYB1,SRCAP,TDRKH,PRDM5,KCNN1,MPP2,MSR1,NPTX1,SLC11A2,NTRK3,PGAM2,PRPH,KHDRBS2,RPS6KA2,PPP4R3A,EPN2,SLC8A1,PLCB1,DOCK9,SLC30A4" Drug 6171_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,MTUS1,APBB2,CDC14B,CACNA1I,THSD7A,CHN2,LHX2,CREM,CSF1,PDE4DIP,OPTN,MBNL2,VPS13B,ETV1,TLR7,EYA1,FER,FGFR1,PCLO,HLF,NELL2,NRCAM,OPRL1,SERPINI1,PTPRN2,TMEM231,GALNT10,SH3BGR,PPM1E,CPEB3,KDM4B,TACR1,IQCE,TRIM2,TPM1,AMACR,TRIM9,PRDM10,KCNAB1" Drug 7123_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "BRAP,AMPD2,APBB2,CDK10,RGS20,MPDZ,BCL7A,RAB29,CAMK2G,KRIT1,SOCS5,PDE4DIP,DCAF8,TBC1D5,SPATA2,SUGP2,MBNL2,SCML2,FGFR1,ANKFY1,DISC1,SMIM7,MAPK3,TMEM231,PID1,ZDHHC14,MAP6D1,KBTBD4,STX1A,EXOC7,FBXW11,KIAA0930,ZEB1,TRPM2,HIRA,FAM155A,UBE3A,KLC2,HPS4,VPS35L" Drug 2778_UP Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ALCAM,PPFIA3,BACH1,SYNJ1,CFAP410,CACNA2D1,CBFA2T2,CNTN1,CABP1,SH2B1,CSF1R,CNTNAP2,DOCK4,PLXNC1,FHL1,IQCG,GPER1,TJAP1,IL6ST,JAK2,MAN2A2,MAP4,MSI1,NF1,GPR85,POLG,PRKAR1B,MAPK10,ZNF493,ZDHHC14,KCTD17,ZFHX4,RPS6KA2,KCNIP1,LIMCH1,KDM4C,ELOVL4,TK2,PARD3,PHTF2" Drug 7049_DN AH6809; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABHD6,ALDH7A1,RIPK1,NRP2,SYNJ2,CA12,SPAG9,PLEKHB1,QKI,IQCK,VCAN,FAM131B,TBC1D5,GIT2,DBN1,EDIL3,RGS17,FHL1,ERAP1,GLYR1,PCLO,AGFG1,TJAP1,IL6ST,JAK2,MBNL1,PLEC,RPS20,FUZ,CCDC88A,BTBD7,SMARCD3,KDM4B,DOK5,SPTAN1,SS18,SZT2,TNS1,METTL3,WIPF1" Drug 413_UP trichostatin A; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "APOC1,ARNTL,ARRB1,PLA2G4C,BMP7,MTMR3,RAB29,CAMK2A,CLTB,ARHGEF4,DTNB,OPTN,MBNL2,ENO2,OLFM1,FHL1,FYN,CYP46A1,USP19,RAB40B,BTN2A1,RNFT2,MITF,PDE4A,SERPINI1,PRPH,PTCH1,GAL3ST4,RGS3,PPM1E,SLC9A5,SMARCD3,DOP1A,ZSWIM8,ZNF423,TRIM2,CDH22,WIPF1,CLIP2,ZNF184" Drug 6698_DN Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "TRMT9B,CDC42BPA,PDE8B,MARK4,EIF4G3,ST3GAL5,SYNJ2,SCAPER,KRIT1,LRRFIP1,FOXN3,NRXN3,RAB26,NCOR2,ARMCX2,SGSM2,CELSR3,COQ7,SCARA3,AFF2,ATP2C1,ERAP1,INPP5K,SLC11A2,RETREG1,FA2H,MAPK7,WDR25,C1orf54,ZNF671,MAPK12,FBXO11,MYH15,SPTAN1,DDN,THSD1,TMEM121,TK2,LMF1,WIPF1" Drug 4321_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,FUBP1,CACNA1I,RUNX1T1,CRLF1,ARHGAP22,TBC1D5,MAML1,DTNA,MAMLD1,EDN1,HIPK3,EPB41L2,ZNF549,CSPG5,B4GALNT1,SYT17,PRUNE2,ITGA7,ITPKA,LAMA2,SMAD1,TAGLN3,NPR2,NPTX2,OPRL1,PRKAR1B,RASGRF1,RGS4,RGS12,RNASE1,EMID1,FAM214B,SLC11A1,ZC3H13,IQSEC2,DMXL2,GPR161,ICAM5,NDRG4" Drug 2112_UP Nimesulide [51803-78-2]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADORA2A,CDK13,ZSCAN18,KIF1A,LARGE1,PLEKHB1,HOMER3,RCHY1,ARHGAP24,PLPPR4,MRNIP,NCALD,ZNF549,HPCAL4,SEPT9,GLYR1,GPD1,STON1,TPPP,CACFD1,GUCY1B1,BACH2,SMAD9,GIT1,NF1,NPR2,CNTLN,RIPOR1,RGS4,ATXN7,SLA,ZKSCAN3,HECW1,SAMSN1,MCF2L,TBL1X,VIPR2,VLDLR,ZNF24,SLC17A7" Drug 3992_UP Phenacetin [62-44-2]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADD2,MTUS1,ANK2,CDK13,ADAM23,AZGP1,NRP2,CACNA1G,BAIAP3,VAX2,LY86,CABP1,C2CD2L,SV2B,EDNRA,HIPK3,CELSR3,DCTN2,OGA,GATM,NEU3,GNAO1,KIT,LSS,NTRK2,ACSS3,C1orf54,RASGRF1,BEND5,RFX2,SLC4A3,PKNOX2,SLC11A1,HECW1,NFASC,MCF2L,OBSL1,PCDHA5,TPM1,PHTF2" Drug 2884_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,AP2A2,APLP1,PPFIA3,RUNX1T1,CDO1,B4GALT6,FHL5,GSDME,CELSR3,TNK2,HSD17B14,FGFR3,BAIAP2,AGAP2,SRCAP,DIDO1,BTN2A1,ICA1,KCNH2,KIT,ADAM22,PCBP3,MINDY2,TRIM68,EMID1,SCN8A,RASA3,SLC9A5,LIMCH1,SNCA,SOX15,ARC,SYN2,WSCD1,KIAA0930,NDRG4,MAP3K12,GDPD5,ADAMTSL3" Drug 2569_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,C1QTNF1,APBB2,ATP1A3,BMP7,BAIAP3,CDO1,ABCG2,HOMER3,CREM,PDE4DIP,SLITRK5,E2F5,MBNL2,COQ7,ANKMY1,SIGLEC8,GATM,PRUNE2,PCLO,GUCY1B1,MYH3,ZNF862,PPARA,CEP41,KLK6,ZFHX4,EMID1,RXRA,SMPD3,ASAP3,PKNOX2,SLC11A1,SNCA,DOP1A,DNAH7,ZNF34,TIAM1,TRO,MPPE1" Drug 5022_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AP2A2,NME5,BIN1,AMT,APBA2,CA4,HAP1,KYAT1,RCBTB2,STOML1,ARMC8,NECTIN3,ENTPD4,CSF1R,RIMS2,PPP6R2,DAPK3,MFAP3L,FGF12,FGFR3,PRELID3A,TRAF3IP2,CNTRL,TJAP1,MMP16,MSI1,ADAM22,ZNF862,PDE4A,PLCD1,WDR25,NKAIN1,SOX3,SPTAN1,PHLDB1,ASTN2,EXOC7,IQCE,XRCC4,UPF3A" Drug 1686_UP Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "TRMT9B,APC,ARHGDIG,SLC4A4,ADAM23,ARHGEF7,B4GALT6,RAB28,NECTIN3,DCAF8,TBC1D5,DMPK,NR1D2,NCALD,FGFR1,PDLIM5,ALDH1L1,USP19,GRIK5,KCNQ3,AFF1,NF1,WDR25,GSTCD,RXRA,PPP4R3A,LIMS2,TSNAXIP1,KDM4C,STX1A,PLCB1,FBXW11,SZT2,THRA,TK2,TRIO,LMF1,SPHK2,SLC30A3,PHTF2" Drug 4734_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG3,NDRG2,LTBP4,DOC2A,TRMT9B,FAM131A,CDC14B,PLA2G4C,ATP2A2,CA4,TAOK2,PLAA,CNTNAP2,RIMS2,MFAP3L,EDNRA,HSD17B14,DLC1,PDLIM5,USP19,TDRKH,STON1,MEF2C,MID1,MYT1,NFYA,RETREG1,MBOAT7,POLG,PPP5C,PEX26,LIMCH1,DOP1A,UNC5B,STX1A,PLCB1,PCDHA5,THRA,TRIO,SPHK2" Drug 490_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADD2,KIAA1324,C1QTNF1,LTBP4,ALK,ANK2,AZGP1,GYG2,HAP1,CCK,TAOK2,CREM,SLC12A6,RGS17,STX2,NCALD,ZNF589,SCARA3,RUNDC3A,PTPRT,GSTM5,FAM107A,GUCY1A1,STMN1,ADAM22,MSR1,NELL2,NNAT,NTRK3,PDCD2,GPR173,SUSD4,RGS4,ATXN2,SMARCC2,SMARCD3,OBSL1,TNS2,TNS1,WIPF1" Drug 2099_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "BRAP,APC,SHROOM2,MARK4,NUMB,FOXN3,HOMER3,DMTF1,EDN1,EDNRA,MPP6,SEPT9,COPS8,PRRC2B,BTN2A1,INPP5B,ITPKB,KIF2A,MX1,PDE1C,PFKFB2,NLE1,ZNF426,GTDC1,MCMBP,SH3BGR,PEX26,FAM214B,KDM4D,KBTBD4,ARHGEF9,SYT1,TCF4,NSD1,FRYL,UBTF,UPF3A,VPS35L,FZD3,AAAS" Drug 2734_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "DNAH17,AZGP1,MPDZ,KSR1,THSD7A,MTMR7,CDH2,LARGE1,CHRNA4,ABI3BP,CRMP1,HAPLN1,ARHGEF10,EDN3,SRPK3,FHL1,NSG1,GABRA3,ZNF44,SEPT9,GFER,SOX21,KCNJ5,MBNL1,MGAT3,NOVA2,PCSK5,KHDRBS2,CCDC92,EPN2,KANSL3,SYNE2,SYT5,IQCE,TIAM1,TRIO,OSBP2,XRCC4,FAM13C,JPH3" Drug 6303_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,ATP6V0A1,NRP2,CACNA1G,CALB2,CAMK2B,ARHGAP33,CRMP1,AATK,RGS6,CHRDL1,CDON,MRNIP,STX2,ETV1,RRAGB,BAIAP2,AFF2,FYB1,ZNF44,TRAF3IP2,ERAP1,SIGLEC8,GCNT2,USP19,LPAR4,ATXN2L,LIG4,MT1M,MYO7A,NOVA1,PPARA,SAMD9,CCDC40,SNAP25,KIAA1107,PCDHGA10,TRO,ZNF74,KCNAB1" Drug 4499_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "BEGAIN,BCAS1,CDC14B,NRP2,CFLAR,STOML1,COL9A3,AKAP5,NCOR2,CSF1,ARHGEF10,PDE4DIP,DRP2,DTNA,PIPOX,FGF12,LYVE1,SPACA9,CACFD1,AP4S1,SOX21,ICA1,MAN2A2,MMP17,ZNF862,NPR2,PDE4D,RETREG1,KCTD17,FRMPD1,CPEB3,SLA,SLC2A5,SLC6A11,RBM34,RBM26,MCF2L,SLC44A1,THRA,VIPR2" Drug 1566_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG3,CDC42BPA,RASL11B,BCL7A,CAMK2G,P2RX6,ARHGAP33,FAM189A2,TMEM184B,DCAF8,SPOCK2,C2CD2L,FAM13A,APH1A,ING4,ENO2,EVL,POMT1,TRAF3IP2,NEU3,ALDH1L1,PCDH17,LILRB4,DIDO1,AGFG1,IFI16,MX1,MYT1,NTRK3,GPSM2,NLE1,EPB41L4B,TRIM68,C12orf49,SAFB,AMBRA1,SLC6A8,CDK19,PHLDB1,VPS35L" Drug 3369_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,AP2A2,TRMT9B,APAF1,APBB2,GAS7,ATP1A3,LDLRAD4,CACNA2D1,SEPT7,SULT4A1,BRINP1,TMCC2,HSD17B14,ERCC2,AFF2,KHDRBS3,GAD1,NEU3,GPER1,GRB10,GRIK5,TJAP1,KCNH2,KCNQ3,LSS,ADAM22,PDE1C,CEP41,CCDC40,ZDHHC14,SYN2,WSCD1,CRTC1,PARD3,TNS1,TRPM2,SLC17A7,KCNAB1,PLSCR4" Drug 3383_DN Hymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,LTBP4,SEMA7A,APBA2,FAM131A,SLC2A11,CA12,HAP1,USP2,ASIC3,SIPA1L1,PHF14,ARMCX2,DLC1,FGFR1,PDLIM5,DHX35,ICA1,IL6R,IL6ST,INPP5B,LYRM9,CDK18,PLTP,LRP12,POLG,PRKAR1B,PTPRO,FAM184A,KCTD17,AMBRA1,PKNOX2,KDM4B,CAMTA2,THSD1,SMG6,DMXL2,CRTC1,PCDHA6,ZNF24" Drug 2290_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "APC,GAS7,MTMR2,CACNA1I,CACNA1G,CFAP410,SULT4A1,HOMER3,CPS1,CREM,CRMP1,DAPK1,MBNL2,EIF4G2,ERCC2,PIPOX,HPGDS,PRUNE2,GPER1,KIF5A,MAN2A2,MAP4,PALM,PFKFB2,GDPD2,TRIM68,RFX3,SEMA6D,ST6GAL1,SNAP25,DOP1A,ARHGAP26,SPART,ATP10B,EXOC7,ZEB1,TNS1,PIK3R5,TRPM2,FLRT2" Drug 5392_UP Metolazone [17560-51-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "CDK13,SCAPER,CAMK2G,SLC16A4,ARHGEF1,CBFA2T2,CACNA2D2,B4GALT6,CREM,INTS1,PLXNC1,TENM1,MTSS1L,RRAGB,FHL1,DISC1,GATM,GLYR1,POLL,PRRC2B,CNTRL,RASSF8,ATXN2L,KCNH2,MAP4,MARK1,AFF1,MMP17,PCDHGC3,CDK18,GPR85,LRP12,PPP5C,CEP41,ASAP3,FBXO11,KIAA1107,KIAA0930,DNALI1,KCNAB1" Drug 1078_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ST3GAL5,RAB29,WASF1,RAB26,SOCS5,USP6NL,DBN1,PARD6A,RCAN1,STX2,ARMCX1,BAIAP2,SEC23B,CSPG5,FYN,SYT17,KCNMB4,HSF2,FAM69A,MAP4,MAPT,MIA2,PFKFB3,STRN3,MBOAT7,PRKACB,PRKAR1B,PTPN13,SUSD4,SMARCC2,ZBTB43,ELOVL4,STXBP1,MTCL1,TRIM2,BHLHB9,BEX4,REEP1,ZNF184,EVI5" Drug 5257_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,ALCAM,APBA2,SEMA4G,CFLAR,SYNJ1,SYNJ2,GYG2,ARHGAP33,RAB28,TPP1,CNTNAP2,TBC1D5,MFAP3L,EXOG,DTNA,EZH1,FER,OGA,RAB30,RASSF8,DHX35,NEK1,NF1,NFYA,PCDH9,PRKAR1B,ZDHHC14,ZFHX4,CARF,TCP11L1,BTBD7,COA1,ZHX3,PLCB1,PARD3,CABIN1,CDK20,LMF1,GDPD5" Drug 3869_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,ADRA1D,APAF1,CDC14B,ADAM23,PROM1,GYG2,CACNA2D1,CHRNA4,TAOK2,STOML1,CNTN1,SEC14L5,FGF13,FGFR1,AGAP2,NEU3,GLI2,PCLO,GRIK5,GRM2,KPNA5,KITLG,MID1,ADAM22,NNAT,PFKFB2,ABCB1,STRN3,VPS13C,ZSCAN32,RGS12,ZFP2,ST6GAL1,SNCA,PHLDB1,TBCEL,DOCK9,TMPO,LAT2" Drug 2104_DN Flufenamic acid [530-78-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADCY6,CDC42BPA,APBB2,APLP1,MARCH3,MPDZ,LHX2,HINFP,PDE4DIP,GIT2,DMTF1,IRAK4,MFSD10,GAD1,GLUL,RNFT2,AGFG1,MIA2,SLC11A2,PDCD2,PIK3R1,POLG,SAMD9,GTDC1,RIC8B,RPS6KA2,SAFB,MAPK12,SBF1,SUPT20H,EPN2,KDM4D,CDK5RAP2,PDZD2,ST5,TTBK2,ARHGEF9,TCF4,SIN3B,AAAS" Drug 6465_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AP2A2,APBA2,GAS7,SLC4A4,N4BP2L1,SGCE,CAMK2B,HIP1R,QKI,SULT4A1,WHRN,COL9A3,HAPLN1,OSBPL3,DCAF4,SPOCK2,ZNF589,FER,AGAP2,AFF2,GAD1,SIGLEC8,HLF,KCNJ5,KCNN1,CNOT4,NLE1,LRP12,RELN,SAMD9,C1orf54,CCDC25,RPS6KA2,ASAP3,SNCA,PDZD2,SPP1,TRIM2,TLR4,KCNAB1" Drug 4331_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "APAF1,PPP4R4,CACNA1I,CFAP410,CD38,PLAA,SULT4A1,RIMS2,DAPK1,BRINP1,SNX29,EDNRA,PLXNC1,ELN,ETV1,GPR75,ADAMTS13,ICA1,IL6ST,KCNJ5,MAP4,TM6SF1,MMP16,NOVA2,TREM2,PIK3R1,STRN3,PRKAB2,PBRM1,STUM,RBM34,SP4,IZUMO4,SYN2,ICAM5,CA14,FLRT2,NT5M,SLC17A7,KCNAB1" Drug 5298_UP Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ALCAM,APOC1,CDK10,ST3GAL5,CRLF1,CACNA2D2,TAOK2,VAX2,HOMER3,NCOR1,VCAN,PDE4DIP,GIT2,CNNM1,MRNIP,STX2,BAIAP2,SEMA4D,FYN,CNTRL,DIDO1,KCNH2,MAP4,MBD1,NEK1,PLCD1,LRP12,GTDC1,RPS6KA2,FNDC3A,KDM4C,THSD1,RGL1,STX1A,TRIM2,HEY1,RUNDC3B,LMF1,GDPD5,MPPE1" Drug 3298_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AMPD3,CDC42BPA,SEMA7A,APC,CFLAR,CACNA1I,HAP1,SCARB1,CLGN,FOXN3,SLIT2,SULT4A1,CNTN1,LYPD1,ELN,DLC1,OGA,HPGDS,ADAMTS13,GRM8,IL6R,KCNQ3,PDE4B,PLCB2,PLCD1,LRP12,MINDY2,CEP41,PTPRN2,ASAP3,ARHGEF40,SLC9A5,SNCA,ST5,JMJD6,KIAA1107,HEY1,CA14,DNALI1,ITM2C" Drug 6368_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ALK,APC,DNAH17,CFAP410,CAMK2B,CHN2,CABP1,NRG2,C2CD2L,LYPD1,ELN,NCALD,FYB1,GLI2,LILRA2,SOX21,SHISAL1,TAGLN3,ZNF862,NF1,PDE4B,PDE4D,LRRN3,CEP41,MARCH1,PID1,RASGRF1,BEND5,ZNF821,ANKRD6,SLC11A1,DOP1A,SPTAN1,SYT1,TPM1,TPM2,TRO,CA14,VGF,XRCC4" Drug 7252_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AMT,CDC42BPA,ST3GAL5,CBFA2T2,SCARB1,TAOK2,NRXN3,QKI,FAM131B,SNPH,DBT,LYPD1,EDIL3,DENND4A,FLT1,CGREF1,TMEM8B,RNFT2,IFI16,SHISAL1,TJAP1,FAM69A,LIG4,CNOT4,PALM,PTPRN2,RGS4,AP1AR,SIRT2,SMARCD3,LIMCH1,KDM4B,SPTAN1,SYT1,CHST8,TK2,ZNF45,NT5M,HPS4,PHTF2" Drug 2742_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ACHE,APBA2,CACNA1G,CDH2,CHRNA4,AKAP6,NCOR2,PDE4DIP,SRPK3,SIGLEC8,GFER,RUNDC3A,GNAL,SOX21,SCIN,MAPT,MBNL1,MGAT3,AFDN,ADAM22,MYO6,NPY,PPP1R1A,RGS4,NUDT11,SUGCT,CCDC92,EPN2,KANSL3,SPART,CLSTN2,ASTN2,SYT5,TIAM1,TRIO,TRO,XRCC4,SEMA3B,FAM13C,JPH3" Drug 3903_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,NDRG2,TRMT9B,AMPD3,APAF1,MARK4,SLC4A4,RUNX1T1,RCBTB2,ARHGEF6,AKAP7,WHRN,NCOR2,CNTNAP2,RUSC2,C3orf18,F5,FGFR1,FGFR3,FHL1,CAMKK2,SPACA9,HLF,IFI16,IGF1,TJAP1,KCNN2,KPNA5,MX1,PFKFB2,PURG,MARCH1,KLHDC8A,EMID1,ZFP2,IZUMO4,ARHGAP26,SYN2,CUX2,VIPR2" Drug 3351_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,ASIC1,CDC42BPA,KCNAB2,APLP1,CDC14B,PDE8B,BMP7,MTMR3,WHRN,NCOR1,CSF1,ARMCX2,EGFR,STX2,FAM49B,STON1,CNTRL,KCNJ5,SMAD1,TM6SF1,MPP2,NF1,PLCD1,PRKAR1B,MAPK10,GRAMD1C,PTN,TCP11L1,FAM214B,IQSEC2,SPART,TROVE2,THRA,RUNDC3B,VIPR2,WIPF1,KCNK12,REEP1,RNF146" Drug 3890_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "BIN1,N4BP2L1,RUNX1T1,SEPT7,CNTN1,SNCAIP,SNPH,SPOCK2,DYNC1I1,RCAN1,ELN,SPEG,CORO2B,DLC1,CAMKK2,CPLX2,PCDH17,NXPH3,IRF8,TJAP1,IL6R,MEF2C,MID1,AFDN,ADAM22,MYT1,NNAT,PCDH9,PDE4A,PDZRN4,CEP41,SAMD9,ELOVL2,GAL3ST4,KCNIP1,IZUMO4,PEG10,ZC3H13,SYN2,SLC30A3" Drug 5669_DN Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADCY6,AP2A2,APOC1,MARCH3,ATP6V0A1,BCL7A,CFLAR,KYAT1,HOMER3,PDE4DIP,ARMCX2,OPTN,ING4,ANKMY1,FHL1,IQCG,GLYR1,AGBL5,IPO5,MATK,MID1,ADAM22,NEK1,SNX10,PRKAR1B,PRPH,SNRK,TMEM104,FUZ,AMBRA1,BTBD7,LIMCH1,ASTN2,EXOC7,AP4E1,HIRA,PLPPR2,ZBTB14,MAP3K12,EVI5" Drug 4195_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,APC,KIF1A,SYNJ2,ARHGAP22,LHX2,ARMC8,WHRN,RGS6,MBNL2,PLXNC1,MTSS1L,ST3GAL6,CINP,SEPT9,GRM8,SOX21,SHISAL1,SCIN,MAPT,MN1,NOVA1,RETREG1,CNNM2,ZCWPW1,KHDRBS2,RGS4,SUGCT,SBF1,FRMPD1,KANSL3,ZNF415,DDN,GPR161,TIAM1,TIMP4,TNS1,VIPR2,NT5M,KCNAB1" Drug 2767_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NME5,SEMA6A,ALCAM,MARK4,N4BP2L1,SYNJ1,SYNJ2,GYG2,CACNA1I,HAP1,CAMK2B,HOMER3,AKAP7,SH2B1,DTNA,DLC1,FHL1,CAMKK2,OGA,GRM2,HNMT,KCNB1,KCNJ5,MAP4,NF1,CLDN11,ELOVL2,ASAP3,SLC11A1,SPTB,SAMSN1,DMXL2,CRTC1,CHST8,TRPM2,FAM155A,XRCC4,NDRG4,EMSY,PHTF2" Drug 3380_UP Carbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "RALGAPA1,ADORA1,KIAA1324,FAM135A,APBB2,ATP2B2,N4BP2L1,MTMR3,CA4,RUNX1T1,SULT4A1,CNR1,PDE4DIP,SPOCK2,TMCC2,TNK2,ANKMY1,DISC1,RUNDC3A,GRIK5,TJAP1,KCNJ5,ADAM22,MX1,NNAT,NPR2,PGAM2,PLXNB1,C19orf57,PPARA,SEMA6D,STUM,CXXC4,ARC,ZEB1,SZT2,DOCK9,PIK3R5,TRPM2,VLDLR" Drug 6323_DN Cefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABR,MTUS1,C1QTNF1,BIN1,APC,MARK4,MYRF,SEPT7,NCOR2,SIPA1L1,PDE4DIP,DCAF8,SPOCK2,OPTN,DENND4A,ANKMY1,FGF1,ANKFY1,SRCAP,RASSF8,MBD1,MPP2,TAGLN3,FSD1,PPARA,PPP5C,CNNM2,FUZ,AMBRA1,NLGN1,TMCC1,ERC1,SPTAN1,IQSEC2,ZBTB43,ELOVL4,TBCEL,KIAA0930,PLPPR2,TFIP11" Drug 1658_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,AK2,AMPD3,CDC42BPA,CFAP410,CAMK2B,CAMK2G,ARHGEF1,SCARB1,CNOT8,HOMER3,SH2B1,DCAF4,DTNA,EXTL2,OLFM1,DISC1,SPACA9,GRIK5,PADI2,ACOT7,LSS,MEIS2,MIA2,SCAMP5,MMP16,PPP2R2B,FBXW7,FNDC3A,ZHX3,SPART,CEP68,STX1A,PLCB1,TRIM2,METTL3,TRPM2,VGF,WIPF1,XRCC4" Drug 3094_DN S-(+)-ibuprofen [51146-56-6]; Down 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,APOC1,MARK4,CAMK2B,CDO1,B4GALT6,CREM,SLITRK5,ECM2,PLXNC1,F5,KAT8,OLFM1,FYB1,TRAF3IP2,GATM,MAN1B1,KCNN1,MAP4,MEF2C,ZNF862,NF1,PDE4A,PFKFB2,PLEC,PTCH1,PTN,RIPOR1,CEP97,BEND5,ZNF821,CPEB3,TMCC1,ATP10B,PLCB1,SZT2,CRTC1,HSPBP1,PLPPR2,FAM13C" Drug 2317_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABR,ALCAM,BIN1,APC,APOC1,CDK13,MARK4,SCAPER,CBFA2T2,HOMER3,FAM169A,PPP6R2,MFAP3L,DNM1,TOM1,COQ7,NCALD,PRELID3A,SEPT9,INPP5K,POLL,GRIK5,GSN,KCNH2,KCNN2,NFYA,PCDH9,MINDY2,BTBD7,KIF13A,UNC5B,CAMTA2,TTBK2,PHLDB1,STX1A,SYN2,KIAA1107,CRTC1,BHLHB9,KAT6A" Drug 4647_UP Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,ASIC1,GAS7,DDO,AQP6,PPP4R4,SYNGR3,CHN2,PCYT1B,COL9A3,AKAP5,NCOR2,RGS6,PDE4DIP,MFAP3L,EZH1,FGFR1,FYB1,GABRA3,SIGLEC8,GLI2,CACFD1,IRAK3,HLF,KCNF1,SMAD1,MATN3,MBNL1,MGAT3,NTRK3,CNNM2,ZMAT4,SLA,ARHGEF40,SNCA,ZHX3,CLSTN2,SYN2,NT5M,EPM2A" Drug 4526_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AGT,PPFIA4,PPP4R4,ADAM23,NRP2,KSR1,SCAPER,CALB2,CAPN3,USP2,CABP1,NRG2,CNTNAP2,DTNA,ELN,FGF1,FGFR1,FLT1,DCTN2,PDLIM5,HPGDS,LILRA2,GRM8,ICA1,LIFR,LSS,MN1,ADAM22,MSR1,NRCAM,OXTR,PTPRH,CCDC40,KHDRBS2,RBM34,ZEB1,THRA,TLR4,VIPR2,KCNK12" Drug 5425_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "SEMA6A,ARRB1,CFLAR,CFAP410,TPP1,QKI,CREM,CNTNAP2,FCF1,OPTN,EIF4G2,VPS13B,FGFR1,PRKAG2,FHL1,INPP5K,GLYR1,RAB30,HNMT,IL6ST,JAK2,KPNA5,LSS,KITLG,NF1,NFYA,NTRK2,OXTR,STRN3,ZSCAN32,CEP97,CLIP1,BTBD7,PLCB1,EXOC7,TRIM2,RPGRIP1L,CABIN1,KCNK12,EMSY" Drug 4407_UP Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "C1QTNF1,BEGAIN,ARHGDIG,AZGP1,CACNA1I,RHBDL1,TAOK2,NRG2,CNTNAP2,RIMS2,TMCC2,DTNB,EDN1,EPHB1,FAM198B,FGFR1,FUT9,GPR162,LSS,ADAM22,MSR1,NTRK2,OGG1,GPR85,C19orf57,PRKCB,SAMD9,RFX2,RGS12,SH3GL3,CPEB3,SLC2A5,SLC11A1,OGDHL,LIMCH1,ERC1,PLCB1,WSCD1,TK2,UCHL1" Drug 3461_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,SEMA6A,AMT,SEMA4G,ARHGDIG,PLA2G4C,RASL11B,SLC2A11,ATP6V0A1,CACNA2D1,HAP1,PICK1,ENTPD4,SH2B1,GIT2,VPS13B,FGFR1,IQCG,PDLIM5,SRCAP,GFER,FICD,MAP4,ADAM22,OGG1,PRKAR1B,MAPK7,ZSCAN2,ZDHHC14,SUPT20H,SNCA,ZHX3,TTBK2,PLCB1,SYT5,TRIM2,SLC30A3,GDPD5,SEMA3B,ITM2C" Drug 3503_DN Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABHD6,AP2A2,AK2,APC,APOC1,NCOA1,RIPK1,BCL7A,CFAP410,SYNGR3,SRSF11,LRIG1,HDAC4,RCAN1,DTNA,ING4,CDKL3,VPS26C,SMC2,CACFD1,HNMT,ITPKB,MAP4,ADAM22,PLXNB1,POLG,PRKAR1B,CNNM2,WDR25,ZCWPW1,GTDC1,GSTCD,SH3BGR,ZFP30,NUBPL,UNC5B,CLASP2,SS18,PHLDB1,TK2" Drug 5604_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AK2,LTBP4,APBA2,GAS7,PDE8B,MARK4,SLC2A11,SYNJ1,GYG2,KYAT1,STOML1,CRY2,FAM169A,PPP6R2,MFAP3L,C2CD2L,DTNA,HIPK3,TNK2,MRNIP,SRCAP,ADAM28,GNG4,GRIK5,KCNH2,LRRN3,TMEM231,EMID1,KCNIP1,SH3BP2,ASAP3,FAM214B,LIMCH1,ASTN2,PCDHA5,DICER1,CABIN1,CDK20,HPS4,SEMA3B" Drug 3604_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,SPARCL1,LTBP4,AMPH,APLP1,MARK4,ATP2B2,ADGRB1,CACNA2D2,RCBTB2,TAOK2,DGKG,DPP6,TNK2,C3orf18,RASGRP2,PIPOX,F5,DCTN2,FYB1,MALT1,RUNDC3A,GPER1,PCLO,GSTM5,MBP,NELL2,OPRL1,MASP1,ELOVL2,RNASEL,PNMA8A,ASAP3,SYN2,TCF4,TPM2,UCHL1,NT5M,PRDM10,SLC17A7" Drug 6133_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "SYN3,FZD9,MARK4,RIPK1,SYNJ2,MTMR3,CH25H,HIP1R,CBARP,CHN2,SLIT2,CREM,CSF1,EXOG,HS3ST2,EDNRA,MBNL2,VPS13B,DLC1,FGFR1,NSG1,GATM,PRUNE2,CACFD1,NXPH3,ICA1,SCIN,KCNJ5,MT1M,NPTX1,RFX2,CARF,PNMA8A,FRMPD1,TMCC1,SPTAN1,TBCEL,CRTC1,WNT7A,MKRN3" Drug 5519_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABHD6,MTUS1,APC,CASK,CFLAR,ST3GAL5,SCAPER,SRSF11,NECTIN3,PDE4DIP,GIT2,MAMLD1,MRNIP,COQ7,VPS26C,ANKMY1,FECH,SEMA4D,TRMO,CIT,KIF2A,ADAM22,KLK6,ZCWPW1,RGS12,SBF1,AMBRA1,FBXO11,SLC22A4,MCF2L,EXOC7,FBXW11,TIAM1,TPM1,TRIO,TSC2,TFIP11,VPS35L,MPPE1,KAT6A" Drug 5636_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABHD6,EP400,APC,GAS7,MARK4,NCOA1,SCAPER,GYG2,KYAT1,CBFA2T2,ARHGEF2,BAG4,SIPA1L1,MFAP3L,FBXL5,ING4,ZNF589,BAIAP2,RASSF8,KCNH2,MPP2,PCDH9,PLEC,RETREG2,PRODH,TMEM104,WDR25,ROBO1,NEK11,ABLIM3,ZHX3,EXOC7,TMEM121,TK2,BHLHB9,PARD3,TPM1,HIRA,SLC17A7,TIGD6" Drug 5639_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,ALCAM,BIN1,PPP4R4,MARK4,CACNA1I,CLGN,CRLF1,DOCK4,DBT,MFAP3L,RRAGB,INPP5K,ALDH1L1,GCNT2,GLYR1,RAB30,IL6ST,INPP1,LMO2,MAP4,NEK1,CNOT4,PPARA,MINDY2,SAMD9,ZSCAN32,FAM214B,SIRT2,DOK5,TROVE2,TTBK2,PLCB1,DICER1,SLC44A1,TNS1,KCNK12,ZFP37,SLC17A7,PHTF2" Drug 1855_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "PPP4R4,ARRB1,N4BP2L1,BMP7,C5,CAMK2G,TPP1,CNTFR,ARMC8,CREM,DAPK1,ZBTB24,TAOK3,FECH,SRCAP,DBF4,ICA1,LSS,NEFH,ENPP2,PPP5C,TMEM104,CNTLN,PTPRN2,PLPPR3,TRA2B,SH3BGR,FUZ,DZIP1,PEX26,ZNF667,TMCC1,TSNAXIP1,DBNDD2,ZEB1,SMUG1,TRPM2,BCL2L13,MAP3K12,EPM2A" Drug 5078_DN Dapsone [80-08-0]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADCY6,MTUS1,PPFIA3,EIF4G3,HIP1R,RCBTB2,ARMC8,NCOR1,VCAN,PPP6R2,GIT2,EGFR,HSD17B14,ETV1,EFCAB2,ATP2C1,GAD1,IL6ST,MAPT,ZNF862,NFIX,PDE1C,PLCD1,PTCH1,RAD51D,SCN8A,SIRT2,COA1,SPTAN1,ZBTB43,CEP68,PDLIM2,IQCE,TCF4,ZNF34,TK2,ZKSCAN5,XRCC4,TFIP11,EVI5" Drug 6646_UP Progesterone [57-83-0]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1D,AGT,PRX,PDE8B,ADGRB3,CFLAR,KALRN,SCARB1,CNTN1,NCOR2,CSF1,CNTNAP2,INTS1,BRINP1,DTNA,EBI3,TNK2,ETV1,FGF12,AFF2,SHISAL1,ITGA7,KCNJ5,AFDN,ADAM22,NTRK2,OGG1,PTPRB,RGS12,SLA,ATP10B,PLCB1,MCF2L,PCDHGB6,AP4E1,TRO,FLRT2,KCNK12,KCNAB1,FAM13C" Drug 7485_DN Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AK2,CDC42BPA,PKP4,PPFIA3,CDK13,RIPK1,SLC25A14,KRIT1,LHX2,HOMER3,CLOCK,CREM,NCOR1,PPP6R2,DCAF8,ZFYVE16,KIAA0586,GIT2,FBXL5,DTNA,STX2,CGREF1,GHR,HMGCL,GIT1,CNOT4,POLG,PPP3CC,NKAIN1,TMEM231,RGS3,MAPK12,ZKSCAN3,COA1,CDK5RAP2,LHPP,CLASP2,MTCL1,NDRG4,ZNF184" Drug 3834_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "KIF1A,ADAM15,TAOK2,DAPK3,MFAP3L,EGFR,ELN,HSD17B14,VPS13B,CDKL3,FGFR1,CGREF1,SRCAP,GFER,GLYR1,GPD2,STON1,HNMT,ICA1,LSS,MBD1,KITLG,ZNF862,NEK1,NF1,NFYA,PLCD1,LRP12,ZSCAN32,FERMT1,ASAP3,FUZ,SLC6A8,SNCA,PLCB1,SYN2,KIAA1107,LAT2,REEP1,PHTF2" Drug 3204_UP Practolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADRA1B,NME5,ALK,GAS7,N4BP2L1,CA4,KYAT1,MTMR7,CBFA2T2,ARHGEF2,ABI3BP,GREB1,DCAF8,EGFR,AASS,REEP2,ZNF589,FHL1,PRELID3A,ICA1,IGF1,MAN2A2,ADAM22,NOVA2,PPARA,PPP1R1A,MASP1,ZSCAN2,SUGCT,TCP11L1,RPS6KA2,SCN8A,ASAP3,SLC22A4,SAMSN1,TACR1,OBSL1,UBE3A,XRCC4,SLC30A3" Drug 7314_UP Nifenazone [2139-47-1]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,FAM135A,KCNAB2,EPB41L5,APOC1,MARK4,ALDH7A1,BAIAP3,SCARB1,STOML1,ENTPD4,ARHGEF10,RUSC2,SPOCK3,IRAK4,ABCA8,ZNF589,BAIAP2,TRMO,INPP5K,SPACA9,ATXN2L,ELOVL5,MATN3,SCAMP5,MYH3,NDP,NF1,CCSER2,CNNM2,FAM184A,RGS4,RXRA,ASAP3,THSD1,SYT1,EXOC7,THRA,WIPF1,ZNF74" Drug 3333_DN Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AK2,APBA2,APC,BCAS1,CDK10,CFLAR,RAB29,SOCS6,FAM169A,TBC1D5,DAPK3,DBN1,KAT8,IQCG,PDLIM5,GNG4,RASSF8,DHX35,KCNH2,MIA2,MPP2,LYRM9,NF1,OCRL,MINDY2,PRKAR1B,TMEM231,RGS12,RPS6KA2,SAFB,SYBU,SMARCA4,SPTAN1,PHLDB1,EXOC7,SMG6,ZKSCAN5,PLPPR2,VGF,EMSY" Drug 6286_DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "CDC42BPA,APLP1,ADAM15,BCL7A,RAB29,NRG2,PPP6R2,RASSF2,RHOBTB1,ST3GAL6,POMT1,FYN,DISC1,INPP5K,MSL3,GNG4,GPR37,IDH3A,FAM69A,MEIS1,FSD1,PRPH,CNNM2,PTX3,SH3TC2,CCDC25,ZC3H14,KIF16B,IFT122,SPATA7,ELOVL4,STX1A,PDLIM2,CABIN1,RUNDC3B,HIRA,TRIM9,UPF3A,NAV3,ACTR3B" Drug 5593_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADORA1,FAM135A,APAF1,APOC1,DNAH17,ADAM23,AZGP1,CFAP410,CAMK2B,HIP1R,KCNAB3,CLGN,LHX2,CNN3,AKAP5,AATK,CSF1R,VCAN,PDE4DIP,SPOCK2,MTSS1L,DCTN2,DISC1,GNAL,GRIK4,SOX21,IFI16,NTRK2,PDE1C,LRP12,ENOX1,SEMA6D,SH3BP2,PCDHGB6,TPM2,FLRT2,GDPD5,SLC17A7,KCNAB1,ITM2C" Drug 5505_DN Chrysin [480-40-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "APBB2,APC,APOC1,SLC4A4,SYNJ2,AKAP7,IQCK,ARMC8,AKAP12,NCOR1,PDE4DIP,KIAA0586,EXOG,COQ7,PDLIM5,GAD1,DISC1,MALT1,PRRC2B,KIF2A,MAP4,MIA2,NFYA,CCSER2,PRKAR1B,PRPH,PTCH1,NKAIN1,RGS3,TTC17,ZSWIM8,CDK19,IQCE,CLASP1,SSBP2,HIRA,REEP1,ZNF189,SH3GLB2,EVI5" Drug 5073_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADD2,ALK,AMPH,NRP2,SCAPER,BAIAP3,CALB2,CAPN3,DGKI,CHN2,CABP1,CRYBB1,AATK,SUSD5,RIPOR2,EDN1,MRNIP,CALCRL,AFF2,EFCAB2,ERGIC3,SIGLEC8,POLL,HLF,ICA1,ADAM22,PDE4B,GPR85,PFKFB4,RETREG1,DCHS2,PID1,RGS12,EMID1,SLA,ZHX3,ZNF225,NT5M,SEMA3B,FAM13C" Drug 1639_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASPHD1,ABHD6,NDRG3,SRPX,ST3GAL5,GYG2,RAB29,PLAA,WHRN,RCAN1,EGFR,FYN,COPS8,POLL,KCNMB4,GNG4,GRIK5,FAM69A,MPP2,ZNF862,PALM,PDPK1,RETREG1,PRPH,PTCH1,RAD51D,CARF,NEK11,PPM1E,TSNAXIP1,ZBTB43,AP4E1,BEX4,ZKSCAN5,VAV1,VGF,REEP1,MAP3K12,HPS4,SMIM8" Drug 2741_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "BIN1,PPFIA4,DNAH17,MPDZ,KSR1,DLGAP1,CHRNA4,HAPLN1,NCOR2,AATK,SIPA1L1,PPP1R16B,SEZ6L2,HEYL,FHL1,ZNF44,SIGLEC8,SEPT9,MGAT3,AFDN,MMP16,MYO6,NPY,PPP1R1A,KHDRBS2,FRMPD1,CCDC92,ZNF415,SYT1,SYT5,TACR1,TRIM2,TRIO,TRO,UBE3A,LMF1,KCNK12,XRCC4,ZNF711,SEMA3B" Drug 4172_DN Fillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,LTBP4,AMPD3,MARK4,CFLAR,SYNJ1,SYNJ2,ASIC3,VAX2,WHRN,SNCAIP,PDE4DIP,GREB1,HIPK3,VPS13B,LRRC17,IGSF6,ZNF589,GAD1,TMEM8B,SEPT9,GLYR1,RAB30,GPER1,ADAMTS13,GSN,SHISAL1,KCNN1,NNAT,POLR2F,PPP2R2B,PRKCB,MAPK10,TCP11L1,SBF1,ASAP3,ARHGEF40,AP4E1,TRO,UCHL1" Drug 6420_UP Orlistat; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ABHD6,ADCY6,ADRA1D,MTUS1,APC,APOC1,ARRB2,CDK13,MARCH3,CACNA1A,CDH2,SRSF11,CLCN3,NECTIN3,CPS1,SEMA3D,EGFR,ETV1,BAIAP2,DISC1,GLYR1,FERMT2,DHX35,KCNH2,MIA2,GIT1,MX1,CNOT4,PFKFB2,SNRK,C1orf54,MCMBP,MAPK12,ZFP30,SH3BP2,SYT1,THRA,MAP3K12,MPPE1,FZD3" Drug 4767_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "SYN3,ASIC1,AMPD3,GAS7,SEPT7,CDO1,QKI,SULT4A1,FAM149A,AKAP6,HAPLN1,AATK,RUSC2,C2CD2L,PRELID3A,CHL1,GAD1,ERAP1,PRUNE2,ICA1,KCNH2,SMAD1,AFDN,ADAM22,NTRK2,CDK18,PFKFB2,PLCD1,PPP2R2B,PRKCB,TCP11L1,SH3GL3,CNKSR2,PKNOX2,CDK19,ATP10B,ZEB1,TNS1,AP3B2,SENP7" Drug 3766_DN Dicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ASIC1,NME5,ALK,AMPD3,GAS7,ARHGEF1,PLEKHB1,B4GALT6,NRXN3,SLC4A8,CSF1,DAPK3,EDN1,ETV1,PTK2B,FGF1,POLL,BACH2,HNMT,SHISAL1,ITPKA,ZNF862,PCDH9,SERPINI1,RETREG1,ZSCAN32,ACSS3,NEK11,TCP11L1,ZFP30,ASAP3,AMBRA1,KDM4B,POGZ,STX1A,SYT1,IQCE,TCF4,TNS2,VLDLR" Drug 1687_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,AMH,KCNAB2,APBB2,LDLRAD4,PLEKHB1,SULT4A1,MFAP3L,CDON,ING4,HSD17B14,RRAGB,REEP2,FGFR1,PRELID3A,ERAP1,TXNL4A,CNTRL,SPACA9,GRIK5,GSTM5,TJAP1,MBD1,MGAT3,NFYA,CNOT4,PCDH9,LRP12,PRPH,NEK11,SUPT20H,PPP4R3A,BTBD7,USP33,IQSEC2,CEP68,ARC,EXOC7,KCNK12,ZNF74" Drug 2207_UP Betonicine [515-25-3]; Up 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "MTUS1,BIN1,CDC42BPA,BMP7,HIP1R,CACNA2D2,STOML1,CNTN1,AKAP6,SIPA1L1,RIMS2,SV2B,FAM13A,MTSS1L,ERBB2,ZNF44,INPP5K,MPP2,NTRK2,PGAM2,PIK3R1,PLEC,POU6F1,MAPK10,RELN,PTN,PLPPR3,ASAP3,SNCA,ZHX3,HECW1,ZBTB43,SPART,ATP10B,SYN2,EXOC7,TCF4,SLC35G2,KLC2,SLC17A7" Drug 4591_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "GAS7,BCAS1,FUBP1,CBARP,SOCS6,CHN2,AKAP5,CSF1,ARHGEF4,RUSC2,DMPK,DTNB,AASS,ETV1,BAIAP2,DENND2A,ERAP1,CNTRL,HSF2,IFI16,ITGA7,JAK2,TM6SF1,NPTX1,PDE4A,MAPK10,CEP97,CCDC40,RGS12,PBRM1,FBXW7,KCNIP1,ST6GAL1,LIMCH1,SPTAN1,PCDHGA10,CRTC1,AP4E1,TNS1,PHTF2" Drug 7432_UP Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "LTBP4,PPFIA3,ARHGDIG,CFLAR,ST3GAL5,NECTIN3,PDE4DIP,ZFYVE16,GIT2,ARMCX2,FBXL5,COQ7,DENND4A,VPS26C,SEMA4D,GALC,SRCAP,POLL,GRB10,GRIK5,RNFT2,ATXN2L,MAP4,ADAM22,SLC11A2,CCSER2,KCTD15,NLE1,PLCD1,MBOAT7,PTCH1,ZSCAN32,RIPOR1,TMCC1,PLCB1,EXOC7,HEY1,TRIO,VLDLR,MAP3K12" Drug 4165_DN Trimethadione [127-48-0]; Down 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADORA1,SPARCL1,AMPD3,GAS7,MARK4,SEPT7,CRMP1,SNCAIP,CSF1R,RASSF2,GIT2,DBN1,PLXNC1,ERCC2,FHL1,AFF2,SEPT9,GSN,TJAP1,MAP4,KITLG,ADAM22,NLE1,MTRF1L,LRP12,PRKCB,C1orf54,TRIM68,ZFHX4,ZNF821,SH3BP2,SLC9A5,VPS13A,PLCB1,EXOC7,RPGRIP1L,TRPM2,FAM155A,PLSCR4,EPM2A" Drug 1837_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "NDRG2,FAM135A,AMT,CDC42BPA,ARNTL,MARK4,SLC4A4,BACH1,HIP1R,LARGE1,ARMC8,KIAA0753,PLXNC1,GFER,COPS8,GNAO1,GNG4,IL6R,IL6ST,KCNQ3,KIT,MAP4,GIT1,N6AMT1,PIK3R1,RIPOR1,EXD2,FERMT1,SLC2A5,LIMS2,ZNF430,MAPKBP1,SNCA,DOK5,KIAA1107,TCF4,NPDC1,ZNF74,REEP1,ST7" Drug 6367_DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "ADORA2A,AP2A2,C1QTNF1,APBB2,MYRF,CFAP410,SLC16A4,SCARB1,CDH2,QKI,COL9A1,RASSF2,RCAN1,EDNRA,HEYL,MBNL2,PLXNC1,VPS13B,KHDRBS3,TMEM8B,CPLX2,MGAT3,ADAM22,NNAT,MAPK7,PTPRN,RPS6KA2,SCN2B,NLGN1,LIMS2,CCDC88A,CXXC4,LIMCH1,RBM34,ARHGAP26,CLSTN2,ZEB1,SYNE1,DOCK9,CLIP2" Drug 5999_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AMPH,KCNAB2,SEMA4G,CFAP410,CRMP1,HAPLN1,DMPK,EDNRA,EGFR,ANKMY1,FLT1,PDLIM5,NSG1,FYB1,ALDH1L1,MALT1,GNG4,CNTRL,IRF8,KCNH2,LIG4,ADAM11,ADAM22,MSR1,MX1,PPARA,PPP2R2B,RASGRF1,ZDHHC14,RORB,KCNIP1,SEMA6D,SCN8A,SH3BP2,SLC11A1,SMARCD3,DOK5,SSTR2,DOCK9,UBE3A" Drug 6898_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 2.09E-03 2.35E-02 40 196 "AP2A2,BIN1,APBB2,SYNJ2,AP4M1,TPP1,STOML1,QKI,HOMER3,CREM,ENTPD4,PDE4DIP,APH1A,VPS26C,FHL1,B4GALNT1,DISC1,GLYR1,INPP5B,NF1,PCDH9,PLCD1,PLEC,MAPK7,WDR25,RAD51D,ZDHHC14,SH3BP2,FRMPD1,PREX2,PEX26,ARHGAP26,IQSEC2,MTCL1,FBXW11,CRTC1,TK2,HIRA,LAT2,TIGD6" Drug CID000104751 BAPTA Stitch 1.67E-04 1.00E+00 2.13E-03 2.40E-02 59 324 "PHF12,ARHGDIA,ATP2A2,ATP2B2,BID,CACNA1A,CACNA1B,CACNA2D1,CALB1,CALB2,CALM1,CAMK2B,CCK,KRIT1,P2RX6,LRBA,CRLF1,CHRNA4,MYL6B,CNR1,SACS,EDN1,EDNRA,EIF4G2,PTK2B,PPP1R1B,CAMKK2,ATP2C1,GABRG1,GABRG2,KCNMB4,GRIA2,GRIN2C,GRIN2D,GRM2,GRM8,MYLK2,IGF1,P2RX7,P2RY1,PLCB2,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTK2,RYR3,MAPK12,FNDC3A,SLC6A11,PLCB1,CABIN1,TRPM2,PLD4" Drug CID000000681 dopamine Stitch 1.67E-04 1.00E+00 2.13E-03 2.40E-02 113 715 "DGCR6,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,OSBPL6,OSBPL8,AMT,ATP1A3,ALDH7A1,RGS9,CACNA1A,CACNA1B,CACNA2D1,CALB1,CALB2,CALM1,CBS,CCK,CBFA2T2,NOG,CHRNA4,HOMER3,CNR1,COX4I1,CREM,CSNK1E,HDAC4,GSDME,SLC29A4,ENO2,ZMYND10,PPP1R1B,OLFM1,FGF14,FYN,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,INPP5K,SULT1C4,GNAL,LOXL3,GPR37,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,LINGO1,GUCY1B1,HBA1,TNFAIP8L3,HLF,IGF1,IL12A,KCNJ5,PACRG,BEX5,NPY,NPR2,OGG1,OPRL1,FXYD1,PPP2R2C,PPP2R5E,PRKCB,NDUFS7,PTX3,PPP2R3C,QDPR,RET,RGS4,LRRK2,CLIP1,ZNF354C,RYR3,SAFB,MAPK12,SLC6A11,SNAP25,SNCA,SST,SSTR1,SSTR2,ADHFE1,STX1A,SUPT5H,SYN1,SYN2,SYP,SYT1,TACR1,MLST8,CUX2,ACTR6,NR2C2,HIRA,UCHL1,CLIP2,SLC17A7,NELFE" Drug 7387_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.71E-04 1.00E+00 2.18E-03 2.45E-02 37 177 "MTUS1,SHROOM2,ARNTL,MARK4,ST3GAL5,USP2,WHRN,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,FGF13,BAIAP2,FYN,GUCY1B1,FAM69A,MATN3,KITLG,TAGLN3,PCDH9,SERPINI1,PRPH,ENOX1,RGS4,RPS6KA2,SH3GL3,ASAP3,DOP1A,ARHGAP26,SPTAN1,THSD1,RGL1,SYT1,SSBP2,TRIM9,PLSCR4" Drug 4362_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-04 1.00E+00 2.20E-03 2.48E-02 39 190 "BIN1,AMT,KCNAB2,PLA2G4C,HAP1,CLGN,SOCS6,LHX2,TPP1,SH2B1,CNTNAP2,DAPK3,GIT2,DTNA,RRAGB,PDLIM5,TPK1,INPP5K,PCDH17,GLYR1,GRIK5,IL6ST,INPP1,KITLG,MMP16,PIK3R1,LRP12,NKAIN1,TCP11L1,MAP6D1,SEC14L1,RASA3,ASAP3,FUZ,PEX26,EXOC7,PDLIM2,REEP1,RNF146" Drug 4500_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-04 1.00E+00 2.20E-03 2.48E-02 39 190 "ADRB2,SYT13,AMPD3,APAF1,BCAS1,CDK13,ATP6V0A1,MTMR3,TAOK2,NRXN3,SULT4A1,HOMER3,CABP1,AKAP5,CSF1,PDE4DIP,SPOCK2,DBT,AMOTL2,FLT1,PDLIM5,FYB1,GFER,PDE1C,PFKFB2,SERPINI1,C19orf57,CEP41,PTPRD,PTX3,RASGRF1,FRMPD1,KANSL3,FAIM2,ZHX3,SPP1,DOCK9,VGF,ZNF225" Drug 2189_DN Acacetin [480-44-4]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-04 1.00E+00 2.20E-03 2.48E-02 39 190 "ADRB2,MTUS1,ARRB1,NCOA1,RCBTB2,AKAP7,ARMC8,PDE4DIP,SLITRK5,HDAC9,TNK2,EIF1,RASGRP2,SYNCRIP,POMT1,PDLIM5,INPP5K,SRCAP,DIDO1,SLC2A6,IRF8,IFI16,JAK2,AFF1,PLCB2,MINDY2,SNRK,RET,GALNT10,ARHGEF40,FNBP1,DBNDD2,ZC4H2,CEP68,TCF4,SLC44A1,KAT6B,TPM1,MPPE1" Drug 7519_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.73E-04 1.00E+00 2.20E-03 2.48E-02 39 190 "ASPHD1,NME5,BIN1,ADGRB2,CFLAR,FUBP1,CFAP410,CACNA2D2,PLEKHB1,ARMC8,WHRN,AKAP12,CSF1,CSNK1E,CTH,DAPK3,PARD6A,DPH1,OPTN,FER,CGREF1,MPP6,GAD1,USP19,GRIK5,BTN2A1,INPP5B,JAK2,ELOVL2,PTPRH,RGS4,TCP11L1,ASAP3,SLC22A4,TROVE2,LAT2,SEMA3B,KCNAB1,MPPE1" Drug 5587_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-04 1.00E+00 2.20E-03 2.48E-02 39 190 "SYN3,ADD2,ADRA1D,APAF1,DDO,SCAPER,CNTNAP2,ING4,SPEG,OLFM1,OGA,GLYR1,STON1,PCLO,SPACA9,GRIK5,LMO2,MAP2,MARK1,ADAM22,TAGLN3,MX1,LYRM9,ZNF862,NNAT,NOVA2,SERPINI1,LRP12,PTCH1,ZNF493,CARF,SCN8A,SH3GL3,CDK19,ATP10B,TAL1,UBE2H,FLRT2,KCNAB1" Drug ctd:D002118 Calcium CTD 1.78E-04 1.00E+00 2.26E-03 2.55E-02 83 495 "ASIC1,ADCY5,ADRA1D,ADRA1B,ADRB2,PCDH19,AGT,TAOK1,PARG,ARRB2,ATP1A1,ATP2A2,BTK,CACNA1I,CACNA1G,C5,CA4,CACNA1A,CACNA1B,DDR1,CACNA2D1,CALB1,CALM1,USP2,CD38,CACNA2D2,CHRNA4,CNR1,PICK1,CDC42BPB,CSNK1G3,CYBB,DMD,NR1D2,FIS1,EDN1,EDN3,EDNRA,EGFR,F8,PTK2B,FGF1,FGFR1,CAMKK2,GABBR1,GHR,GRIA2,IGF1,IL6ST,JAK2,KCNH2,KCNN2,KCNN3,STMN1,MYO5A,NEFM,NF1,NUCB2,OXTR,P2RX7,P2RY1,PAX6,ABCB1,PKD1,POU6F1,PPARA,PRKCB,MAPK3,MAPK4,PTH1R,RGS4,RYR3,SLC8A1,SNCA,SPP1,SPTAN1,APOM,SYN2,SYT1,TACR1,TRPM2,UBTF,IFT88" Drug ctd:D015034 Zinc Oxide CTD 1.81E-04 1.00E+00 2.27E-03 2.55E-02 58 318 "VWA5B2,UNC79,APAF1,ATP2A2,KIF1A,ADGRB3,BCHE,CALB1,CHGB,CHRNA4,NGEF,LY86,RAB26,CRYM,SV2B,SEMA3D,SPEG,OLFM1,FGF12,FLT1,CPLX2,GDF1,MSTN,ADAM28,GHR,ELOVL5,IGF1,LSS,MAPT,EFHB,MSR1,TAGLN3,NFE2L2,NPY,NPTX1,PCBP3,NRCAM,PDE4B,MAPK3,ELOVL2,RET,RGS4,ROBO1,CNKSR2,SYBU,SNAP25,ATP10B,SST,ELOVL4,SEPT3,SYT1,SIRT1,TLR4,RIMBP2,NPDC1,NDRG4,FSTL5,MFF" Drug 1737_UP Prenylamine lactate [69-43-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 38 184 "NDRG2,ARNTL,ARHGEF7,UBE2L6,SEC31B,CSNK1G3,DOCK4,BRINP1,KLHL3,MBNL2,OGA,INPP5K,GLUL,IFI16,ITGA7,KCNN1,IPO5,MT1M,MX1,NF1,CNOT4,ENPP2,CCSER2,PLEC,SAMD9,ZSCAN32,SAFB,SGK1,ELMO2,SLC22A4,KDM4B,NXT2,TMPO,R3HDM1,PARD3,ZNF24,UPF3A,NLRP3" Drug 4449_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 38 184 "ADRA1D,SEMA7A,EPS15L1,ARMC8,AKAP6,ABI3BP,CTH,GIT2,DBT,SPOCK3,EDN1,OLFM1,GLI2,RAB30,MSL3,GPR37,SYNPO,IL6ST,MMP16,NACA,OXTR,PDE1C,PDE4B,PDE4D,MBOAT7,PTN,ACSS3,RGS4,KCNIP1,SCN8A,HSPA4L,PDZD2,SP4,ARHGAP26,TBL1X,CDK20,HIRA,EVI5" Drug 3126_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "BIN1,AMT,CDK10,ATP6V0A1,MTMR3,SCARB1,SOCS6,AKAP7,ARMC8,DGKG,SPOCK2,RHOBTB1,VPS13B,FGFR1,GAA,ADAM28,GPD2,PCLO,IRF8,KIT,MAP4,NRCAM,P2RY1,PFKFB4,PPP3CC,CNTLN,SBF1,SEC14L1,RASA3,TMCC1,SPTAN1,IQSEC2,DNMBP,SIN3B,PCDHGA10,TPM2,FLRT2,PLPPR2,ZBTB14,TIGD6" Drug 3867_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "LTBP4,ALK,APBA2,KCNAB2,APOC1,ADGRB1,SGCE,CFAP410,CDH2,CNTN1,AKAP5,CRY2,CSNK1E,PPP6R2,SEC14L5,RUSC2,ING4,SPEG,REEP2,OLFM1,EFCAB2,KCNJ5,KIFC3,MAN2A2,MGAT3,AFDN,MMP17,MX1,OPRL1,TMOD2,NECAB2,PRKCB,SLC11A1,PEG10,SPTB,RBM26,LMO3,ARC,ZEB1,XRCC4" Drug 5887_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "PPP4R4,ARNTL,CDK13,BMP7,CACNA1I,CACNA1G,CACNA1A,CAMK2B,CBFA2T2,AP4M1,HAPLN1,PDE4DIP,EGFR,MBNL2,RGS17,SEPT9,MSL3,LPAR4,GRIK5,SCIN,INPP5B,KIT,MATN3,MX1,PTN,ACSS3,SH3TC2,RGS12,KCTD17,NEK11,FBXW7,EMID1,ASAP3,TSNAXIP1,COBL,ZFPM2,VIPR2,WIPF1,WNT7A,KCNAB1" Drug 3234_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AK2,LTBP4,CDC42BPA,ARHGDIG,ARRB1,CFLAR,SCAPER,B4GALT6,HOMER3,CREM,NCOR1,DBT,FBXL5,CNNM1,EIF5,RGS17,COQ7,STX2,BAIAP2,SEPT9,USP19,GNG4,GPR37,HNMT,IPO5,MAP4,MBD1,NFYA,RETREG1,EMID1,SS18,TTBK2,JMJD6,TIAM1,UBTF,VIPR2,ZBTB14,TFIP11,UBE3B,RNF170" Drug 2749_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "OSBPL1A,NME5,TRMT9B,PPFIA3,CDC14B,ST3GAL5,CRMP1,CSF1R,SEC14L5,SPOCK2,SPOCK3,SLC12A6,ETV1,FGFR1,FHL1,SIGLEC8,GRM2,BTN2A1,TJAP1,IL6R,KCNQ3,KIT,MAP4,MMP16,NTRK2,CDK18,PRODH,RFX2,RPS6KA2,EMID1,SLC2A5,PKNOX2,IQSEC2,TROVE2,SAMSN1,PHLDB1,TRIO,EMSY,EPM2A,NLRP3" Drug 5668_DN Dimethadione [695-53-4]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "EPB41L5,ARRB1,GYG2,KYAT1,LHX2,VAX2,RCHY1,CSF1R,FAM169A,DCAF8,SPOCK2,MFAP3L,RUSC2,DTNA,ING4,STX2,PRELID3A,OGA,SRCAP,GLYR1,CNTRL,KCNF1,MITF,AFF1,ADAM22,FSD1,CCDC25,SH3BP2,ZNF423,ZBTB43,SPART,CLSTN2,WSCD1,KIAA0930,AMACR,PLPPR2,VAV1,VIPR2,EVI5,TIGD6" Drug 6507_DN Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADCY6,MTUS1,AK2,AMH,CDC42BPA,EPB41L5,CFLAR,SYNJ2,B4GALT6,SIPA1L1,DZIP3,PPP6R2,GIT2,DBT,MFAP3L,EGFR,IRAK4,CDKL3,EZH1,GNG4,GPR37,CNTRL,GRIK5,IL6R,LMO2,MAPT,NF1,OCRL,MAPK7,CCDC25,TRAPPC13,EPN2,UNC5B,SS18,NXT2,EXOC7,KCNK12,ZBTB14,GDPD5,ST7" Drug 3818_UP U-62066 [87151-85-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADGRF5,SPARCL1,FAM135A,CDC14B,ARHGDIG,CDK13,N4BP2L1,NRP2,LDLRAD4,RUNX1T1,EDN3,FRY,ZNF391,PDLIM5,FYB1,TMEM8B,LILRA2,MATK,MGAT3,KITLG,P2RY13,NF1,NOVA2,NPTX1,P2RY1,PFKFB4,C19orf57,PPARA,GAL3ST4,ZMAT4,RGS3,RGS12,PBRM1,EMID1,FAM214B,SSTR2,DOCK9,HIRA,UCHL1,FLRT2" Drug 3063_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SPARCL1,SEMA6A,BIN1,SLC2A11,RGS11,SYNJ2,DLGAP1,TAOK2,FAM149A,RGS6,PDE4DIP,RIMS2,HEYL,SRPK3,ELN,EPB41,ARMCX1,DLC1,CHST15,PRELID3A,SIGLEC8,ADAM28,GFER,ZNF276,GNAL,KCNJ5,MBNL1,PPP1R1A,PTH1R,RASGRF1,SPTB,ATP10B,SSTR2,SYP,DOCK9,TK2,TRO,TUBB1,VGF,KCNAB1" Drug 4545_UP Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AP2A2,APAF1,GAS7,SLC4A4,ALDH7A1,ADGRB2,CACNA1G,SEPT7,EPS15L1,STOML1,C2CD2L,CDON,DTNB,APH1A,IRAK4,SCML2,FGF1,CSPG5,FYB1,GNAL,PRRC2B,CACFD1,ATXN2L,KCNJ5,MGAT3,NCAM2,NF1,NNAT,PRKCB,CNNM2,PTPRN2,CCDC102B,KCNIP1,SH3BP2,IZUMO4,SYNE2,SYN2,ADGRL3,ZKSCAN5,NT5M" Drug 5665_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,LTBP4,CDC42BPA,APBA2,ADGRB3,CACNA1I,HIP1R,MAGI1,CACNA2D2,SLIT2,RASSF2,INTS1,ECM2,TNK2,ELN,LRRC17,ZNF589,FGFR1,KHDRBS3,GPR37,ATXN2L,HLF,TJAP1,KCNH2,PACRG,MEF2C,ADAM22,P2RY1,TREM2,PFKFB2,ZNF493,KLHDC8A,CARF,SH3BP2,SAMSN1,ZC4H2,DICER1,VLDLR,SPHK2,PARP11" Drug 3420_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "C1QTNF3,LTBP4,AMPD3,APOC1,CDC14B,ARHGDIG,ADAM15,CA12,CACNA2D2,B4GALT6,HOMER3,CREM,SNCAIP,DNM1,ING4,ZNF589,FHL1,GPER1,TJAP1,INPP1,LMO2,KITLG,PCDH9,SLC25A23,PRKAR1B,PTN,EMID1,SH3BP2,PREX2,FAM214B,DOK5,EXOC7,KIAA1107,CRTC1,CHST8,FAM155A,SLC30A3,ITM2C,EPM2A,KAT6A" Drug 1317_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,BRAP,APAF1,CDK10,STX16,SYNJ2,SLC25A14,CAPN3,TPP1,IQCK,SEC31B,CSF1,PCOLCE2,EIF1,VPS26C,PDLIM5,MAP4K5,AGBL5,HSF2,LIG4,LSS,MAP4,NF1,CNOT4,C1orf109,GTDC1,SAFB,SUPT20H,SH3BP2,FNDC3A,TROVE2,ZC4H2,NXT2,CEP68,RGL1,PDLIM2,FBXW11,TBL1X,UBE2H,ZNF32" Drug 3195_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "TRMT9B,APC,PPFIA3,CDK10,ST3GAL5,MAGI1,TAOK2,QKI,CSF1R,CTH,ARHGEF4,PARD6A,EDNRA,FGFR1,ANKFY1,ZNF44,SRCAP,AHDC1,MALT1,POLL,LPAR4,INPP5B,LMO2,KITLG,MPP2,LYRM9,EMID1,SBF1,FNDC3A,SOX3,CLASP2,THSD1,SMG6,TRIM2,PCDHA5,ZNF34,CABIN1,TPM1,RUNDC3B,ZKSCAN5" Drug 4239_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,PPP4R4,N4BP2L1,ATP6V0A1,ADGRB1,ARHGAP33,TAOK2,ARHGAP22,VAX2,CNTN1,CSF1,CNTNAP2,MAML1,DBT,SV2B,NCALD,ETV1,REEP2,PTK2B,DCTN2,GALC,GNG4,STON1,GRIK5,CACFD1,SCIN,KIT,SMAD1,ADAM22,MSR1,NTRK2,CNNM2,GDPD2,PTPRH,PBRM1,NFASC,OBSL1,TNS1,UCHL1,PDIA2" Drug 7194_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ABHD6,AK2,BIN1,APAF1,APBB2,EPB41L5,CDK10,ST3GAL5,SCAPER,USP2,PICK1,SMARCAL1,CREM,DZIP3,TBC1D5,C2CD2L,TOM1,FEM1B,PHF20L1,ZNF589,AFF2,FYN,GLYR1,MSL3,NF1,NRCAM,PDPK1,PRKAR1B,TMEM104,NEK11,TROVE2,ARHGEF9,EXOC7,TNS2,PCDHA5,PARD3,CABIN1,LMF1,REEP1,MAP3K12" Drug 5925_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,AMPD3,APBB2,ATP2B2,ADGRB2,CFLAR,CACNA2D1,CAMK2B,CBFA2T2,CLGN,FOXN3,TPP1,CRYM,SNPH,RUSC2,DTNA,ANKMY1,FER,FGFR1,FHL1,AGAP2,ELOVL5,LIFR,MID1,PDE4D,PLEC,MBOAT7,PPP5C,WDR25,ZNF821,FNDC3A,CXXC4,LIMCH1,FAIM2,SS18,STX1A,TRIM2,DNAH7,SLC17A7,DPF3" Drug 3740_DN Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "C1QTNF1,ADGRF5,C1QTNF3,ALK,ADGRB2,BCL7A,LARGE1,ASIC3,LHX2,FAM189A2,PICK1,CSF1,PDE4DIP,ARHGEF4,DMPK,CDON,FGF1,FGFR1,SEMA4D,MSL3,TDRKH,MAP2,CNOT4,PCBP3,PDPK1,MAPK7,PTCH1,ACSS3,SUSD4,ZCWPW1,SLC14A1,DDN,DOCK9,DNAH7,TMEM121,GPR161,TNS1,VIPR2,TFIP11,GAN" Drug 2533_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "APAF1,CDC14B,PPP4R4,ATP6V0A1,SYNJ1,MYRF,LDLRAD4,CBFA2T2,CDO1,B4GALT6,EPS15L1,CRY2,DZIP3,SPOCK2,HIPK3,CNNM1,EIF1,HSD17B14,ERBB2,OLFM1,BAIAP2,FHL1,PDLIM5,KHDRBS3,SIGLEC8,GNAO1,RASSF8,NCKAP1L,NRCAM,CCSER2,STRN3,CARF,PEX26,DOK5,KIAA1107,TNS1,TRIO,FAM155A,REEP1,PHTF2" Drug 6688_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "LTBP4,APC,NRP2,IL33,CACNA2D1,SCARB1,RCHY1,HAPLN1,PHF14,TBC1D5,HIPK3,EPB41,ETV1,ZNF589,FGFR1,EFCAB2,SIGLEC8,ATXN2L,ICA1,ITPKA,LSS,MYCN,CNOT4,ABCB1,PLCD1,MINDY2,PPP5C,GDPD2,ZSCAN32,PTPRB,RGS3,RPS20,FAIM2,ARHGAP26,ASTN2,DOCK9,PCDHA5,GPR161,ZNF24,PHTF2" Drug 4787_DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "CDC42BPA,PLA2G4C,RAB29,CREM,AKAP12,LRIG1,PDE4DIP,PPP6R2,HDAC4,EDNRA,ENO2,EZH1,FECH,GAD1,TXNL4A,COPS8,MSL3,MAP4K5,IL6R,SETD4,RETREG1,SMIM7,PPP3CC,TMEM231,RET,SBF1,SLC22A4,ZHX3,SPTAN1,TTBK2,ARHGEF9,MCF2L,TIAM1,TSC1,ZKSCAN5,VGF,LMF1,XRCC4,REEP1,HPS4" Drug 3572_DN Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "GAS7,APOC1,PPFIA3,MARK4,CFLAR,CRLF1,AKAP7,SLC4A8,ABI3BP,DBT,C2CD2L,EDNRA,EGFR,ING4,STX2,ANKMY1,INPP5K,USP19,CNTRL,ICA1,MATK,MITF,MPP2,ADAM22,MBOAT7,POLG,FUZ,PPP4R3A,SLC6A8,CCDC88A,BTBD7,MAPKBP1,ZHX3,POGZ,IQCE,SMG6,TMEM121,AP4E1,XRCC4,UPF3A" Drug 3011_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "RALGAPA1,FAM135A,AMPH,CDC42BPA,SEMA4G,PROM1,BMP7,HAP1,USP2,CDO1,CHN2,SULT4A1,CPS1,PDE4DIP,EXOG,SRPK3,DCTN2,ERAP1,RUNDC3A,STON1,SPACA9,SYNPO,SCIN,IL6ST,JAK2,KCNQ3,SCAMP5,AFDN,MPP2,OXTR,PDE4A,FSD1,BEND5,SEMA6D,LIMS2,ZC3H13,CDK19,ATP10B,SSBP2,ZNF225" Drug 3226_DN Zaprinast [37762-06-4]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,BIN1,CDC42BPA,APOC1,USP2,LHX2,EPS15L1,CSNK1E,MAML1,MFAP3L,HSD17B14,GRB10,GRM8,ATXN2L,ELOVL5,HNMT,DHX35,ITPKB,MITF,MMP16,SLC25A23,MAPK7,SAMD9,C1orf54,ZDHHC14,RNASEL,NEK11,RPS6KA2,SBF1,NLGN1,ABLIM3,SMARCD3,RBM34,IQSEC2,PLCB1,EXOC7,NSD1,PIK3R5,TRIO,ST7" Drug 3763_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,ADRA1D,APC,ARRB2,PLEKHB1,LHX2,NRXN3,HOMER3,CNTNAP2,GPRASP1,GIT2,MFAP3L,SGSM2,ANKMY1,OGA,NEU3,GFER,HSF2,IL12A,INPP5B,ITPKA,LMO2,STRN3,PPARA,CNNM2,SAMD9,BEND5,SLC22A4,LHPP,SMG6,GPR161,CABIN1,TNS1,TRIO,XRCC4,MAP3K12,NT5M,HPS4,TIGD6,AAAS" Drug 6466_DN Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASPHD1,AK2,TRMT9B,AMPD3,BIN1,APC,RIPK1,CFLAR,LDLRAD4,B4GALT6,CLCN3,PUM1,MFAP3L,FEM1B,EGFR,PLXNC1,STX2,NCALD,FGFR1,HNMT,IL6ST,MEIS1,MGAT3,NELL2,NPR2,PDE4B,PPP5C,ZSCAN32,KHDRBS2,RGS3,SLC25A36,DCUN1D2,DOK5,IQSEC2,POGZ,MCF2L,SLC44A1,THRA,SEMA3B,SMIM8" Drug 4823_DN Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AK2,APLP1,CDK10,CFLAR,ARHGEF7,CCNT1,SYNGR3,MFAP3L,MTSS1L,NCALD,ANKMY1,ZNF589,ERAP1,DISC1,GNG4,STON1,GPER1,RNFT2,MAP4K5,ELOVL5,HNMT,INPP5B,IPO5,LYRM9,NF1,NFYA,OGG1,SLC25A23,TMEM231,RGS12,SH3BP2,FBXO11,SLC22A4,ARHGAP26,ARHGEF9,VPS13A,SZT2,CRTC1,TK2,ZNF45" Drug 407_UP sodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "RALGAPA1,NDRG2,DOC2A,APBB2,ATP6V0A1,MTMR3,GYG2,RAB29,SYNGR3,LHX2,LY86,CNTFR,AATK,MFAP3L,DPP6,SRPK3,ARMCX1,FGFR1,SEMA4D,GPR37,NELL2,SNX10,PLCD1,VPS13C,C1orf109,TCP11L1,DBNDD2,CLASP2,PRRC2C,ANKRD28,CRTC1,SIRT1,TMEM121,BEX4,TRIO,ZNF45,REEP1,MAP3K12,GDPD5,AAAS" Drug 5781_UP Spironolactone [52-01-7]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,APAF1,CDK10,ARHGDIG,RGS20,ARSE,RASL11B,ATP6V0A1,ADAM23,BMP7,ARHGAP33,LARGE1,ARHGAP22,STOML1,ABCG1,SUSD5,EDNRB,HIPK3,CELSR3,MBNL2,COQ7,MTSS1L,NCALD,REEP2,SEMA4D,STMN2,GSTM5,MAN2A2,MMP17,TAGLN3,NELL2,RGS12,CNKSR2,SNCA,HECW1,ZBTB43,KIAA1107,CHST5,VAV1,SLC17A7" Drug 6412_UP CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "KDM5D,ADORA1,AMPD3,AMPH,OGT,GAS7,CDK13,SYNJ2,NCOR2,CSF1,CYBB,SNPH,SV2B,HIPK3,ERCC2,PIPOX,FGFR3,RASL10A,MSL3,INPP5B,ITGA7,NOVA2,TREM2,PLCD1,PRKCB,GDPD2,PTCH1,CCDC40,RGS12,KCTD17,HUNK,SCN8A,SH3BP2,FNDC3A,OGDHL,SPTAN1,PHLDB1,TNS1,TRIO,VIPR2" Drug 2759_UP Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,APBA2,MARK4,SCAPER,GYG2,CFAP410,SLIT2,CRMP1,DCAF4,SEC14L5,TMCC2,ETV1,ANKMY1,FGFR1,FHL1,TRAF3IP2,TMEM8B,RUNDC3A,LILRA2,GRB10,ADAMTS13,MX1,PLEC,PPP5C,MAPK10,ZNF493,KCTD17,ZFHX4,RASA3,LIMCH1,TROVE2,CAMTA2,ARC,DOCK9,CRTC1,PCDHA5,CHST8,UBE3A,VIPR2,DNALI1" Drug 3409_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SRPX,LTBP4,APBB2,APLP1,ARHGDIG,DNAH17,MARK4,CACNA1I,C5,CAMK2G,PLAA,STOML1,ARMC8,DZIP3,GREB1,INTS1,BRINP1,RCAN1,ELN,FHL1,GCNT2,GLYR1,STON1,ELOVL5,IRF8,KCNH2,KHK,KITLG,MITF,PDE1B,RELN,RBM34,KDM4C,SPTAN1,CLSTN2,PLCB1,CRTC1,PCDHA6,TRIO,SMIM8" Drug 6068_UP Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "KDM5D,SEMA7A,CDK10,ARHGDIG,BAIAP3,LDLRAD4,FOXN3,CHN2,CLTB,SULT4A1,CNN3,RASSF2,DGKG,MYEF2,KLHL3,EGR3,HSD17B14,PRUNE2,GRIK5,ATXN2L,IL6R,KCNH2,KIF5A,MN1,P2RY1,PLCD1,MTRF1L,RET,RFX2,SYBU,SLC2A5,SLC22A4,SNCA,HECW1,SPTAN1,SMG6,TIMP4,UCHL1,SLC17A7,KCNAB1" Drug 3573_UP Azaperone [1649-18-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "FZD9,ADORA2A,SYT13,FAM131A,ADAM23,CA4,CLDN10,USP2,ENTPD2,LHX2,CPS1,ARHGEF4,PLXNC1,FOXF2,ALDH1L1,ADAM28,GFER,TJAP1,KCNQ3,MAN2A2,ADAM22,NTRK2,GPR85,SNRK,GAL3ST4,RPS6KA2,SCN8A,PREX2,SLC11A1,SNCA,IQSEC2,TBCEL,TK2,AMACR,VGF,ZNF45,ZNF154,NT5M,GDPD5,KCNAB1" Drug 6703_UP Mimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1B,DOC2A,APBB2,APC,PTCH2,SLC2A11,FUBP1,CAPN3,CAST,USP2,CHN2,TAOK2,PDE4DIP,PHF14,EDIL3,MBNL2,ETV1,ST3GAL6,GNAO1,PRUNE2,GRM8,ITGA7,LAMA2,KITLG,MSR1,NOVA2,NPTX1,PTPRG,TCP11L1,ZFP30,FNDC3A,DZIP1,ANKRD6,ZNF423,SYT5,RPGRIP1L,PCDHA5,TEK,TIMP4,LAT2" Drug 4758_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "RALGAPA1,AP2A2,LTBP4,APOC1,CDC14B,SEMA4G,MARK4,PTCH2,RGS9,SCAPER,GREB1,DBT,RHOBTB1,SPOCK3,DMPK,DTNA,EDN1,EDNRA,EPHB1,ERBB4,OGA,KCNH2,KCNJ5,SMAD1,SETD4,PLCD1,LRP12,TCP11L1,RPS6KA2,EMID1,CPEB3,CNKSR2,SNCA,KDM4B,SYN2,SYT5,LAT2,KCNK12,XRCC4,SLC30A4" Drug 1481_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,AP2A2,APBB2,CDK13,ST3GAL5,SCAPER,CFAP410,CA4,SOCS6,TAOK2,RIPOR2,SNPH,DMPK,MBNL2,ERCC2,CAMKK2,OGA,ADAM28,ADAMTS13,GRIK5,GRIN2C,IL12A,LSS,MBD1,MGAT3,MMP16,MSI1,CDK18,RETREG1,PLCD1,CEP41,PTCH1,CCDC40,FAM184A,PKNOX2,SLC6A8,MYH15,SYP,IQCE,ST7" Drug 3463_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ALCAM,LTBP4,AMPD3,APOC1,PPP4R4,ARHGDIG,RCBTB2,SLC4A8,DCAF8,DUSP9,EGFR,VPS26C,FGFR1,SEPT9,HNMT,JAK2,KCNF1,MMP17,NF1,NNAT,NTRK2,CLDN11,PRODH,ELOVL2,ZDHHC14,RGS12,ZNF821,ASAP3,ANKRD6,FAM214B,BTBD7,SPTAN1,PHLDB1,VPS13A,EXOC7,KIAA0930,UBE3A,VLDLR,MPPE1,TIGD6" Drug 4135_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,NME5,AK2,APBB2,EPB41L5,PDE8B,MARK4,CFLAR,SYNJ2,CACNA1I,B4GALT6,STOML1,CSF1R,FAM169A,GREB1,TBC1D5,GIT2,DTNA,ING4,FGFR1,FAM49B,GAD1,GLYR1,IL6ST,IPO5,MAP4,NF1,PLCD1,MAPK7,ZDHHC14,CPEB3,COA1,ZHX3,ZBTB43,TROVE2,CLSTN2,KIAA0930,AP4E1,ZKSCAN5,PHTF2" Drug 5796_DN Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AK2,DNAH17,SCAPER,SOCS6,CREM,PDE4DIP,DCAF4,GPRASP1,RUSC2,C2CD2L,KLHL3,HIPK3,EGFR,FGFR1,BAIAP2,ERAP1,SEPT9,CNTRL,SYNPO,ICA1,TJAP1,MAPT,ZNF862,PFKFB2,MINDY2,RAD51D,FBXW7,CSRNP3,AMBRA1,KDM4C,SPTAN1,SAMSN1,SYN2,SYT1,MCF2L,TIAM1,TK2,TPM2,UGT8,ST7" Drug 5332_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ABHD6,APBB2,APC,MARK4,ZBTB10,CA4,NCOR1,GIT2,DBN1,DTNA,RASGRP2,BAIAP2,ERAP1,AGBL5,TJAP1,KCNF1,LSS,TAGLN3,ZNF862,PDE4A,PRODH,PTN,FAM184A,CLIP1,RXRA,FUZ,PPP4R3A,BTBD7,SMARCC2,SNCA,ZHX3,CLSTN2,TRIM2,RPGRIP1L,DOCK9,BEX4,ZNF711,EVI5,MPPE1,MARCH8" Drug 6561_DN STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "RALGAPA1,ASIC1,C1QTNF1,OGT,SHROOM2,CFLAR,AP4M1,IQCK,PREPL,DBT,MAMLD1,HSD17B14,ERCC2,PRKAG2,FHL1,TRAF3IP2,DENND2A,GAD1,SIGLEC8,INPP5K,GPER1,HNMT,MEIS1,MXI1,NOVA2,PTN,FAT4,SUPT20H,ST6GAL1,SLC22A4,KIF13A,TMCC1,CEP68,TK2,CABIN1,TNS1,ZKSCAN5,XRCC4,MPPE1,DPF3" Drug 7150_UP "(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "APC,BMP7,CACNA1G,MYRF,CBFA2T2,RAB26,WHRN,VCAN,CNTNAP2,ARHGEF4,FAM131B,MFAP3L,RUSC2,FAM13A,EZH1,ST3GAL6,OGA,ZNF44,SYT17,SESN1,GRM8,INPP5B,MAPT,NF1,PALM,PRKAR1B,CNNM2,BCAS3,GTDC1,CCDC25,FBXW7,RPS6KA2,SH3BP2,PPP4R3A,ERC1,DDN,ASTN2,TIMP4,TK2,PARD3" Drug 1800_UP Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "BRAP,LTBP4,SLC4A4,CALB2,CNOT8,CPS1,ZFYVE16,GIT2,DBT,ARMCX2,EDNRA,FCF1,ING4,IQCG,TRMO,DLL3,ERAP1,ARFIP1,PCLO,ATXN2L,HMGCR,HNMT,TAGLN3,NF1,NFYA,CNOT4,SAMD9,PTPRE,NEK11,PEX26,CCDC88A,FNBP1,ZHX3,SPTB,NXT2,TCF4,HIRA,NT5M,RNF170,AAAS" Drug 4955_UP Carisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ABHD6,NDRG2,SPARCL1,LTBP4,AMH,APBA2,APC,MARK4,ADAM23,AZGP1,GYG2,HOMER3,CSF1,DUSP9,HIPK3,PIPOX,SRCAP,PRUNE2,ICA1,ADAM22,PDE4B,PDPK1,RETREG1,CEP41,PRKAR1B,ZFHX4,CARF,EMID1,SNCA,ZHX3,HECW1,IQSEC2,ARC,KIAA0930,PCDHA5,CABIN1,PLPPR2,ZBTB14,SEMA3B,EPM2A" Drug 2259_DN "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "RALGAPA1,NME5,FAM131A,APOC1,MARK4,ALDH7A1,HAP1,CCNT1,ARHGAP33,CRLF1,CACNA2D2,FOXN3,SOCS6,CTH,GREB1,EGFR,SRCAP,MALT1,KCNN2,MAP4,ZNF862,MAPK10,GRAMD1C,TMEM104,GSTCD,SBF1,SH3BP2,FERMT1,SIRT2,LIMCH1,STX1A,DOCK9,THRA,TPM1,WBP2,SPHK2,SLC30A3,KCNAB1,KAT6A,JPH3" Drug 3212_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "CDC14B,RGS20,CFLAR,USP2,TAOK2,ENTPD4,DAPK3,DNM1,COQ7,SEMA4D,OGA,SEPT9,GRB10,ELOVL5,HNMT,TJAP1,INPP5B,KCNH2,MAP4,MATK,TM6SF1,MITF,MPP2,NPR2,PCDH9,PLEC,PLTP,RGS12,ZKSCAN3,RBM34,SOX3,ZBTB43,THSD1,PLCB1,ZNF34,TK2,HIRA,PLPPR2,VIPR2,NDRG4" Drug 3584_DN Mesalamine [89-57-6]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "APC,PRX,PPP4R4,ARRB1,DNAH17,MARK4,KIF1A,CA12,TAOK2,SULT4A1,CRY2,MFAP3L,DNM1,EDNRA,FCF1,NCALD,USP19,KCNMB4,ATXN2L,INPP5B,MAP4,MMP16,NF1,CNOT4,NPR2,PLXNB1,STRN3,MAPK7,SH3BP2,ASAP3,FUZ,NLGN1,EPN2,SLC6A8,SLC22A4,KDM4C,SPTAN1,STX1A,EXOC7,WIPF1" Drug 3742_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SLC4A4,ATP2A2,KIF1A,NRP2,MYRF,CACNA1A,ARHGAP22,ABCG2,NRG2,CRY2,NCOR2,MFAP3L,DTNA,EDNRB,ETV1,FGFR1,RAB30,TDRKH,ITGA7,KCNJ5,MAN2A2,MARK1,ADAM22,PDE4A,CEP41,ZSCAN32,KCTD17,RNASEL,SMARCD3,IZUMO4,SPTB,DDN,IQCE,SMG6,AP4E1,TRIM9,SPHK2,REEP1,EVI5,KCNAB1" Drug 4711_DN PNU-0251126 [267429-19-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SEMA6A,DOC2A,APBB2,MARK4,C5,CBFA2T2,BRINP1,ZNF804A,FEM1B,MRNIP,SCML2,ZNF589,FHL1,PDLIM5,GFER,MSL3,GNG4,GRM8,HNMT,KPNA5,MIA2,MPP2,ADAM22,NF1,RETREG1,MBOAT7,MAPK7,SAMD9,RNASEL,SH3BP2,EPN2,KIF13A,CLASP2,THSD1,VGF,VIPR2,XRCC4,DNALI1,KCNAB1,TIGD6" Drug 3006_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SYN3,SPARCL1,AMPH,HIP1R,USP2,DGKI,ARHGAP33,CHGB,WHRN,NRG2,CRYBB1,CSF1,SIPA1L1,SV2B,EDN3,SRPK3,STX2,CORO2B,HPGDS,SPACA9,GRM2,ATXN2L,SYNPO,SCIN,KCNF1,KIF5A,SCAMP5,NEFM,NELL2,DCHS2,ELOVL2,NUDT11,NEK11,TACR1,AP4E1,R3HDM1,TRIO,FLRT2,SLC17A7,HRASLS" Drug 3617_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,TRMT9B,MARK4,GYG2,CALB2,SPOCK3,ERCC2,SPEG,REEP2,PTK2B,DCTN2,ADAM28,GFER,RUNDC3A,PRUNE2,SYNPO,IFI16,ITGA7,KCNJ5,KHK,LAMA2,MBP,MGAT3,MX1,ZNF862,MYT1,NELL2,NTRK2,PLTP,ELOVL2,KLHDC8A,EMID1,SLC11A1,MAPKBP1,PDZD2,TSNAXIP1,ATP10B,SAMSN1,WSCD1,FLRT2" Drug 7071_UP CAY10397; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "BIN1,PPFIA3,CDK13,EIF4G3,CFAP410,STOML1,QKI,PDE4DIP,KLHL3,PARD6A,ING4,MRNIP,BAIAP2,TRMO,ERAP1,SYT17,SRCAP,GPER1,SHISAL1,SCAMP5,MN1,TAGLN3,SETD4,FA2H,SNRK,PTPRN2,SUGCT,TCP11L1,ASAP3,ZNF667,SMARCD3,KDM4B,SPATA7,SPTAN1,CAMTA2,TCF4,SZT2,FAM155A,AAAS,GAN" Drug 1497_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADCY6,ALCAM,FAM131A,CDK10,SYNJ2,CAMK2G,MAGI1,AKAP12,ABCG1,GIT2,ING4,RGS17,EZH1,ZNF589,ZNF276,GNG4,MUM1,INPP5B,ITPKB,MIA2,NF1,SLC11A2,SETD4,SLC25A23,WDR25,NKAIN1,ZCWPW1,MAPK12,FUZ,AMBRA1,FNDC3A,PEX26,BTBD7,SOX3,ZNF423,PHLDB1,KIAA0930,GDPD5,MARCH8,ACTR3B" Drug 4836_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,AMT,MTMR2,C5,CAMK2G,SCARB1,ARHGAP33,RAB28,WHRN,AKAP12,ZNF337,ZNF804A,MFAP3L,MTSS1L,ERCC2,EZH1,KAT8,GPD2,GPER1,TJAP1,TM6SF1,GIT1,NF1,PRODH,RGS12,RNASEL,FBXW7,SUPT20H,SH3BP2,FAM214B,SNCA,TROVE2,TTBK2,PHLDB1,STX1A,TNS2,CHST8,SPHK2,MPPE1,SMIM8" Drug 3385_UP Nizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADD2,ADRA1B,C1QTNF1,ALK,DOC2A,RASL11B,SLC4A4,N4BP2L1,CACNA1I,LDLRAD4,EPS15L1,CLTB,QKI,MYRIP,EDN1,EPB41,ERCC2,OLFM1,FHL1,NSG1,FUT9,PCDH17,GPER1,KCNN1,ADAM22,TAGLN3,CLDN11,TREM2,STRN3,CEP41,RPS6KA2,SALL1,FAM214B,PKNOX2,SLC11A1,OGDHL,FAIM2,PCDHGA10,THRA,SENP7" Drug 5815_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,AK2,OGT,CFLAR,CSF1,CSNK1E,DCAF8,SGSM2,SUGP2,EFCAB2,CINP,PDLIM5,RNFT2,MAP4K5,MAN1B1,DHX35,IL6ST,FAM69A,MAN2A2,MT1M,NF1,NFYA,PLCD1,ZNF426,ELOVL2,RIPOR1,SH3TC2,KIRREL1,AMBRA1,WDR37,ZNF430,SMARCC2,CDK19,ELOVL4,COBL,EXOC7,SATB2,TNS2,TMPO,METTL3" Drug 4959_UP Apramycin [37321-09-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AMPD3,APBA2,EPB41L5,PPFIA3,RHBDL1,CBFA2T2,ARHGAP33,FOXN3,CNTN1,ARHGEF10,PDE4DIP,RASSF2,DUSP9,ING4,TNK2,FGF1,FYB1,STON1,HLF,TJAP1,IL6ST,INPP5B,KCNF1,KCNH2,KCNN1,MX1,NTRK2,PPARA,MASP1,PTX3,FRMPD1,TSNAXIP1,SPTB,PLCB1,THRA,R3HDM1,CABIN1,CLIP2,ZNF711,KCNAB1" Drug 5043_UP Piracetam [7491-74-9]; Up 200; 28.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AK2,ADGRF5,APC,ARRB1,PDE8B,BMP7,USP2,CRLF1,CNTN1,AKAP5,RGS6,RIMS2,MFAP3L,EDNRA,SEMA3D,MTSS1L,PRELID3A,CACFD1,KIT,MATN3,AFDN,ENPP2,GPR85,PFKFB2,PPARA,LRRN3,GRAMD1C,EMID1,ZNF821,SLA,SLC9A5,SLC12A4,SNCA,FAIM2,SPTB,PHLDB1,TRO,RPRM,MKRN3,SEMA3B" Drug 2782_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NME5,BIN1,APC,CDK13,BMP7,CAMK2G,SPAG9,FOXN3,TPP1,HOMER3,PHF14,GREB1,DBN1,MFAP3L,LYPD1,SLC12A6,EGFR,FGF12,GPER1,ATXN2L,IL6R,MAP4,MID1,MSR1,MX1,NELL2,NF1,PLCD1,MINDY2,CEP41,PRKAR1B,SALL1,ZNF821,STUM,FAM102A,ASAP3,ARHGEF40,KIF13A,RGL1,WSCD1" Drug 6063_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASPHD1,C1QTNF3,CDC14B,CFLAR,ST3GAL5,ARHGEF2,HOMER3,CRY2,CSF1,PDE4DIP,DZIP3,GPRASP1,DTNA,HIPK3,FCF1,EGFR,ING4,FECH,GALC,MALT1,GLYR1,GRIK5,IL6ST,ADAM22,NF1,NLE1,MBOAT7,PRKAB2,ZDHHC14,FBXW7,KIF16B,FBXO11,TTBK2,ARHGEF9,IQCE,TRIM2,AP4E1,ZNF34,KCNK12,PHTF2" Drug 4557_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ACTN1,LGR5,RAB28,NRXN3,NRG2,SLITRK5,RHOBTB1,PLPPR4,EXOG,DTNA,EDNRA,PLXNC1,AASS,TENM1,BAIAP2,PDLIM5,PRELID3A,GAD1,MSL3,TDRKH,GUCY1B1,MITF,NFYA,PDE1C,PLXNB1,PPP5C,PTN,PTX3,FAT4,IQSEC2,DDN,ASTN2,TNS2,TNS1,RUNDC3B,OSBP2,WIPF1,HPS4,NAV3,MPPE1" Drug 1367_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ACADM,SHROOM2,ARRB2,BACH1,WASF1,CA12,CAST,KRIT1,SRSF11,RAB28,SOCS5,PPP6R2,RUBCN,HDAC9,FBXL5,C2CD2L,SRPK3,VPS26C,ACSL4,SEC23B,EFCAB2,ERAP1,CRCP,PADI2,HNMT,KTN1,MARK3,PDE1C,ENPP2,RETREG1,PPM1B,EXD2,SCP2,CHD9,KBTBD4,GLT8D1,TTBK2,KLHL7,EVI5,JMJD1C" Drug 3042_DN Carbachol [51-83-2]; Down 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "APBB2,HOMER3,ABI3BP,OSBPL3,VCAN,ZNF337,KIAA0753,RHOBTB1,EXOG,PLXNC1,MRNIP,ST3GAL6,ATP2C1,SEPT9,INPP5K,SPACA9,ELOVL5,KPNA5,SLC25A23,STRN3,LRP12,ZNF493,RET,SEC14L1,MRAS,SH3BP2,CCDC88A,KBTBD4,BTBD7,CAMTA2,SS18,DMXL2,ZEB1,TNS1,SMUG1,TRIM9,MKRN3,EVI5,UBE3B,PHTF2" Drug 5429_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "C1QTNF3,ALCAM,BCAS1,ARHGDIG,CCNT1,ARHGAP33,MAGI1,TPP1,QKI,ARHGEF6,CTH,DTNA,AHDC1,GLYR1,GPER1,GRIK5,ATXN2L,IL6ST,IPO5,LSS,KITLG,ZNF862,NF1,CNOT4,NLE1,LRP12,CNNM2,EMID1,ASAP3,EPN2,LHPP,PLCB1,IQCE,RPGRIP1L,CRTC1,VIPR2,EVI5,SEMA3B,EPM2A,ST7" Drug 3907_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADD2,ADRA1B,CDC14B,RGS20,ASGR1,ADGRB2,SCAPER,MTMR3,CACNA1I,CAMK2B,ARHGEF1,STOML1,AKAP7,ELMO1,KLHL3,RASGRP2,MTSS1L,ERBB4,DLC1,ALDH1L1,GRIK5,ICA1,TJAP1,L1CAM,ADAM22,NNAT,NPTX2,SLC11A2,STRN3,LRP12,MAPK7,GRAMD1C,ZDHHC14,EPN2,SLC8A1,IZUMO4,HECW1,TBCEL,PCDHA5,DPF3" Drug 3363_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "LTBP4,OGT,APC,RGS20,CFAP410,CLGN,STOML1,HOMER3,CNTN1,WHRN,ZNF804A,ING4,FHL1,SEMA4D,CGREF1,OGA,SRCAP,CACFD1,BTN2A1,IL6ST,JAK2,KIT,MAPT,MPP2,ADAM22,NF1,NPTX1,SLC11A2,PLCD1,RASA3,SH3BP2,PEX26,SOX3,THSD1,ELOVL4,STX1A,TBCEL,RPGRIP1L,NDRG4,EMSY" Drug 5459_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NME5,LTBP4,BCAS1,CDC14B,STX16,CFLAR,CBFA2T2,ABI3BP,ENTPD4,OPTN,ANKMY1,FHL1,GLYR1,RAB30,POLL,GRIK5,ITPKB,ZNF862,NF1,NTRK2,LRP12,FAM184A,RGS3,RNASEL,EMID1,SAFB,ZNF430,LIMCH1,SOX3,TSPYL2,SPART,POGZ,PLCB1,PDLIM2,CABIN1,VGF,VIPR2,SPHK2,SEMA3B,EPM2A" Drug 3459_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,AMT,ARHGDIG,RGS20,ATP6V0A1,SCAPER,CAMK2B,CACNA2D2,CNOT8,STOML1,ENTPD4,SIPA1L1,EGFR,NCALD,BAIAP2,IQCG,TPK1,POLL,TJAP1,INPP5B,JAK2,KIT,MAP4,ADAM22,ZNF862,NF1,ZDHHC14,GTDC1,TCP11L1,ZNF821,SUPT20H,PEX26,CXXC4,TMCC1,ZHX3,ARC,CHST8,TRIO,VGF,LAT2" Drug 7142_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "LGR5,ALDH7A1,KIF1A,BID,CFLAR,CFAP410,PTBP2,SCARB1,CHRNA4,RAB28,WHRN,HINFP,CSNK1E,SLITRK5,EGFR,KAT8,BAIAP2,SEMA4D,TRMO,GAD1,TMEM8B,ZNF276,CRCP,RNFT2,ACOT7,SCIN,INPP5B,MAPK7,PTPRN2,ZNF671,SH3BGR,FUZ,OGDHL,CEP68,EXOC7,TCF4,TRIM9,EVI5,VPS35L,MPPE1" Drug 4832_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,BAIAP3,CAMK2B,CACNA2D2,AKAP7,FAM169A,DBT,CDON,DTNA,EDNRA,EIF5,TNK2,NCALD,ANKMY1,SCML2,FER,FGFR1,MSL3,GNG4,STON1,GPER1,HNMT,HSF2,INPP1,KCNH2,KIF2A,NPR2,OPA1,PPARA,PPP5C,ELOVL2,FAM184A,GTDC1,RGS12,CCDC25,BTBD7,CXXC4,SNCA,RGL1,TNS2" Drug 3364_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "KIAA1324,ATP1A3,ATP2B2,AZGP1,CACNA1I,CACNA2D1,CAMK2B,CCNT1,CACNA2D2,CNN3,AKAP6,CNTNAP2,RASSF2,DAPK1,SHANK1,ING4,ERBB2,PTK2B,FHL1,GAD1,RUNDC3A,GPER1,GPR37,GRIK5,ICA1,KITLG,ZNF862,ENPP2,RGS12,KLHL11,ST6GAL1,OGDHL,IZUMO4,ZC3H13,PHLDB1,TNS1,LAT2,PARP11,ADAMTSL3,AP3B2" Drug 4620_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADCY6,ADORA2A,GAS7,CDK10,RGS11,BMPR1B,RUNX1T1,DGKI,NRG2,SH2B1,CSF1,CNTNAP2,EDN3,EDNRB,AGAP2,PDLIM5,FYB1,SIGLEC8,NEU3,GPER1,ITGA7,MMP16,ADAM22,NF1,CLDN11,PPP1R1A,PTCH1,SUSD4,RASGRF1,RGS12,NEK11,TCP11L1,SLC4A3,BTBD7,ZNF423,ARHGAP26,ASTN2,MCF2L,TNS1,GAN" Drug 5045_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "PDE8B,NRP2,LY86,PICK1,WHRN,SPOCK2,SV2B,DMD,DTNA,OPTN,ELN,REEP2,KAT8,DISC1,GFER,GNAO1,PRUNE2,IRAK3,ATXN2L,KCNB1,MSI1,PDE4B,PFKFB2,PRKAR1B,MAPK10,GRAMD1C,RGS12,TCP11L1,FRMPD1,CNKSR2,PREX2,SLC11A1,KDM4B,IZUMO4,ATP10B,PHLDB1,ADGRL3,TBCEL,PIK3R5,REEP1" Drug 3685_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,FAM135A,PDE8B,N4BP2L1,ADGRB2,AATK,CSF1,IPCEF1,PDE4DIP,SHANK1,EDN1,FLT1,NSG1,ALDH1L1,CSDC2,GNAL,GPER1,MMP16,ADAM22,NPTX2,PCBP3,PDE4D,PTCH1,ZSCAN32,PTPRO,RGS4,S100B,ZC3H13,ATP10B,ARC,SYT1,MCF2L,TAL1,ZEB1,TNS1,PDIA2,SPHK2,SEMA3B,KCNAB1,KAT6A" Drug 5309_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ALCAM,DNAH17,N4BP2L1,CFLAR,C5,SYNGR3,FAM189A2,VAX2,DTNA,EGFR,ING4,ELN,VPS26C,FER,BAIAP2,GLYR1,TDRKH,BTN2A1,HNMT,MAP4,PDE1C,PPP5C,WDR25,PTPRE,NKAIN1,FNDC3A,DHX30,ZHX3,SPTAN1,CDK19,THSD1,NXT2,JMJD6,MCF2L,TBL1X,TRIM2,TNS2,PCDHA5,TSN,ZNF24" Drug 885_DN 5186223; Down 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASPHD1,APOC1,GYG2,CA4,KYAT1,CRLF1,TAOK2,LHX2,PARD6A,DNM1,CDKL3,EZH1,FHL1,FAM49B,SYT17,RNFT2,KCNF1,NPR2,SLC11A2,SETD4,OXTR,PRKAB2,PRKAR1B,PRPH,SAMD9,SAFB,SH3BP2,ASAP3,ZHX3,LHPP,IQCE,KIAA0930,PCDHA5,ZNF34,CABIN1,HIRA,VGF,PCBP4,MPPE1,TIGD6" Drug 6354_DN Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AP2A2,MTUS1,CASK,NUMB,SLC4A4,TAOK2,EPS15L1,QKI,FAM169A,ARHGAP32,GIT2,LYPD1,CNNM1,TNK2,FCGRT,BAIAP2,EFCAB2,TPK1,ATP2C1,PRELID3A,SESN1,COPS8,GNG4,IDH3A,JAK2,SCAMP5,SLC11A2,NLE1,PRPH,CLIP1,CSRNP3,ASAP3,AMBRA1,WDR37,SMARCA4,KIAA0930,TNS2,CHST8,NDRG4,MPPE1" Drug 5595_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ALK,EPB41L5,ARRB1,MARK4,GYG2,CACNA1G,CAMK2G,SLC16A4,CBFA2T2,CRLF1,LHX2,STOML1,SH2B1,CSF1,CNTNAP2,MAML1,DAPK3,C2CD2L,EDNRA,DLC1,FGFR1,PRELID3A,GCNT2,GPER1,ADAMTS13,LMO2,MAP4,MSI1,ADAM22,ATXN7,ASAP3,ABLIM3,SLC22A4,SMARCD3,DOK5,DIP2A,ARC,WSCD1,TMEM121,PLPPR2" Drug 7478_DN Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "APBB2,CDK13,CFLAR,KYAT1,SMARCAL1,NECTIN3,PDE4DIP,GIT2,DBN1,MED12,EDNRA,INPP5K,KCNMB4,GRB10,GRIK5,CACFD1,BTN2A1,JAK2,MPP2,OGG1,CCSER2,SLC25A23,STRN3,LRP12,TMEM104,ELOVL2,FAM184A,GTDC1,PEX26,LIMS2,SLC6A8,BTBD7,IFT122,NPL,METTL3,VGF,NDRG4,ST7,SMIM8,GAN" Drug 3752_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ASIC1,APBA2,LHX2,VCAN,CNTNAP2,STX2,CORO2B,FCGRT,FGF1,SCARA3,DISC1,GFER,INPP5B,JAK2,IPO5,SCAMP5,ZNF862,PDE4D,RETREG1,ASAP3,FNDC3A,DZIP1,KDM4D,ELMO2,SMARCA4,RBM34,ATP10B,EXOC7,KIAA0930,ZEB1,TNS2,TIAM1,CBX5,TMPO,TNS1,TPM1,CDK20,PLPPR2,LMF1,TIGD6" Drug 7459_UP Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SYN3,ADRA1D,SLC2A11,BCL7A,SYNJ2,FUBP1,CALB2,CAMK2B,LHX2,RAB33A,STOML1,RCHY1,NCOR2,ABCG1,CYBB,ERCC2,OGA,ALDH1L1,POLL,TJAP1,MAP4,MIA2,ADAM22,PLCD1,PLXNB1,LRP12,MBOAT7,PPARA,WDR25,PTH1R,PTN,ANKRD6,ZC3H13,ATP10B,COBL,VLDLR,LAT2,ZNF24,ZNF45,ADAMTS9" Drug 2972_DN Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,MTUS1,CASK,ATP6V0A1,SCAPER,CFAP410,CAMK2G,SLC16A4,CD86,CLGN,FOXN3,STOML1,PDE4DIP,PPP1R16B,ZNF337,DGKG,SUGP2,EZH1,FGFR1,CGREF1,ADAM28,ELOVL5,MAP4,SCAMP5,SLC11A2,OGG1,PFKFB4,PLEC,POLG,TMEM231,CEP97,ZCWPW1,BEND5,TCP11L1,ANKRD6,MAPKBP1,DOP1A,DDN,AP4E1,MAP3K12" Drug 4504_DN Iopromide [73334-07-3]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADORA2A,SEMA4G,SLC4A4,CACNA1I,CBFA2T2,SYNGR3,MAGI1,LY86,PICK1,CNTN1,CSF1R,SNPH,PLXNC1,TNK2,MRNIP,FGF1,HPCAL4,TMEM8B,SRCAP,GNG4,FERMT2,ELOVL5,ICA1,IL6ST,IL12A,KCNJ5,NF1,NNAT,PIK3R1,PID1,GSTCD,KIRREL1,ZNF671,PPP4R3A,TAL1,AMACR,RPRM,NT5M,EVI5,DPF3" Drug 2308_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADORA2A,BIN1,APBA2,EPB41L5,ATP2B2,ADGRB3,CFLAR,CAMK2B,CLGN,LHX2,AKAP7,FAM149A,AATK,FBXL5,DTNA,EDNRA,HIPK3,EZH1,DLC1,ZNF589,OLFM1,FGFR1,SRCAP,CSDC2,GNAL,ICA1,IRF8,JAK2,NNAT,LRP12,RELN,GAL3ST4,RPS6KA2,STUM,SLC9A5,LIMCH1,VPS13A,PARD3,TPM2,DPF3" Drug 7514_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "KIF1A,NRP2,CALB1,ARHGEF1,AKAP7,NCOR1,CSF1R,SIPA1L1,SEC14L5,TBC1D5,DPH1,TOM1,EDN3,EPB41L2,MPP6,MSL3,ATXN2L,TJAP1,KCNJ5,IPO5,MAN2A2,MYT1,OCRL,CDK18,PDE1C,NECAB2,MAPK7,GSTCD,EMID1,CLIP1,FAM214B,RCOR3,DOK5,HECW1,FBXW11,DOCK9,PIK3R5,TPM2,TRIO,LAT2" Drug 3762_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADD2,APC,BMP7,SYNJ1,MYRF,SOCS6,PLEKHB1,HOMER3,PHF14,FAM13A,PTK2B,CINP,GFER,GLYR1,KCNMB4,ELOVL5,SHISAL1,ZNF862,CNOT4,NPR2,PDE4A,ACSS3,RPS6KA2,ST6GAL1,DZIP1,OGDHL,ZNF415,KDM4B,ZHX3,ATP10B,THSD1,SS18,ST5,ARC,SYN2,SYT1,TBCEL,TIAM1,KAT6A,TIGD6" Drug 7521_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SEMA6A,CDC42BPA,APC,GAS7,BCAS1,ARRB1,EIF4G3,KIF1A,ST3GAL5,CFAP410,CAMK2B,RUNX1T1,SYNGR3,ARHGAP33,TPP1,COL9A3,AKAP12,ABCG1,CTH,GIT2,CRCP,GLYR1,GRB10,DHX35,ADAM22,SLC25A23,RFX2,RGS3,GSTCD,SLC22A4,ZC3H13,ARHGAP26,TSPYL2,NXT2,SZT2,ZNF34,TRIO,SPHK2,TFIP11,FIP1L1" Drug 4014_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AMPH,APC,SLC4A4,ADAM23,RUNX1T1,CBS,CBFA2T2,ARHGAP33,AKAP5,ENTPD4,CNTNAP2,ERC2,DTNB,EDNRA,TENM1,DLC1,NEU3,GLYR1,GRM2,IL6ST,JAK2,MMP16,NF1,NNAT,CNOT4,NPTX1,MAPK10,PTPRN2,RAD51D,C1orf54,GAL3ST4,RNASEL,MRAS,SOX15,ARHGAP26,COBL,AP4E1,NLRP3,AAAS,DPF3" Drug 3455_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ABHD6,AP2A2,B4GALT6,CRY2,CSNK1E,PPP6R2,GPRASP1,KIAA0586,GIT2,PARD6A,E2F5,FEM1B,SUGP2,IRAK4,SEMA4D,PDLIM5,GALC,GLUL,RNFT2,HNMT,CNOT4,ELOVL2,NEK11,FBXW7,NUBPL,ABLIM3,BTBD3,IFT122,TROVE2,LARP4,KLHL7,PLCB1,TACC1,TRIM2,TMPO,HIRA,UBTF,LMF1,CLDND1,PHTF2" Drug 3825_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "BEGAIN,APOC1,BCAS1,ADAM23,NRP2,BMP7,SCARB1,ARHGAP33,HOMER3,HAPLN1,CNTNAP2,SLITRK5,DTNA,EDNRB,RGS17,NCALD,ZNF549,DLC1,PRELID3A,OGA,SYT17,GCNT2,GPR75,POLL,GNG4,ICA1,KCNB1,TAGLN3,LYRM9,RETREG1,PTN,PTPRB,ACSS3,SH3BP2,PREX2,SLC6A11,ARHGAP26,DDN,AMACR,LAT2" Drug 2455_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG3,MTUS1,APAF1,APBB2,APC,CFLAR,BMP7,FUBP1,SLC16A4,LARGE1,CNOT8,PICK1,RCHY1,HAPLN1,FAM131B,DBT,DTNA,MRNIP,EIF1,PTK2B,KAT8,PDLIM5,CAMKK2,GNAL,HSF2,KCNJ5,NNAT,NECAB2,PRPH,IZUMO4,ATP10B,SS18,NXT2,RPGRIP1L,ZNF24,MKRN3,REEP1,KCNAB1,ACTR3B,SENP7" Drug 1514_UP Metolazone [17560-51-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "AMPD3,BIN1,APC,MARK4,ATP1A3,ATP6V0A1,SYNJ2,CACNA1I,CD86,TAOK2,SLC4A8,CRMP1,LRIG1,PHF20L1,RUNDC3A,TXNL4A,ADAMTS13,GRIK5,DHX35,IL6ST,MATK,PPP5C,ZDHHC14,RFX2,KCTD17,KCNIP1,SYBU,FAM214B,BTBD7,SLC22A4,RBM34,KDM4C,ERC1,SAMSN1,TTBK2,RUNDC3B,LAT2,ZBTB14,GDPD5,UBE3B" Drug 3192_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "SEMA6A,ALK,APBA2,NRP2,HAP1,RUNX1T1,ARHGAP33,TAOK2,COL9A3,NCOR2,CSF1,HDAC4,DMPK,RASGRP2,MTSS1L,EPHB1,ZNF589,FGF1,DLL3,SIGLEC8,GPD1,PRUNE2,TDRKH,ITPKA,SMAD1,MEF2C,ADAM22,ZNF862,MYT1,LRRN3,GAL3ST4,RPS6KA2,TROVE2,EXOC7,RPGRIP1L,THRA,PIK3R5,ZNF45,ITM2C,NLRP3" Drug 2922_UP Epitiostanol [2363-58-8]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ABHD6,BIN1,CDC42BPA,PRX,PDE8B,ADGRB1,LDLRAD4,CAMK2B,HIP1R,SEPT7,TAOK2,HOMER3,CNN3,CNTN1,ABCG1,DZIP3,SPATA2,DMD,EDIL3,HEYL,MRNIP,RASGRP2,FGFR1,ZNF276,GLYR1,MBP,NLE1,PLXNB1,NECAB2,WDR25,PTPRN2,TCP11L1,SEC14L1,BTBD7,ARHGAP26,PARD3,UBE3A,CLIP2,KCNAB1,PLSCR4" Drug 5488_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADORA2A,SEMA4G,ARHGDIG,MARK4,ADAM23,MTMR2,ARHGAP33,CNTN1,VCAN,DAPK1,BRINP1,ELN,BAIAP2,ANKFY1,ZNF44,RUNDC3A,STON1,RASSF8,AFF1,NF1,NNAT,RNASE1,ZNF821,RASA3,SH3BP2,PEG10,THSD1,ASTN2,MCF2L,SZT2,CHST8,GPR161,THRA,TNS1,PIK3R5,HIRA,LMF1,EVI5,GDPD5,KCNAB1" Drug 3935_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "NDRG2,APC,APLP1,STX16,GYG2,SLC16A4,CBFA2T2,FOXN3,CNTFR,RCHY1,CPS1,DTNA,FCF1,VPS13B,ZNF589,PRKAG2,CSPG5,RAB30,GRIK5,GSN,IL6ST,KCNH2,MPP2,ADAM22,ZNF862,NPTX1,PFKFB2,MINDY2,PPP5C,LIMCH1,IQSEC2,THSD1,RGL1,PLCB1,PARD3,VIPR2,WIPF1,ZNF24,PHTF2,SENP7" Drug 6055_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-04 1.00E+00 2.27E-03 2.55E-02 40 197 "ADRA1D,APBA2,SEMA4G,KSR1,CA4,CBFA2T2,SEPT7,HOMER3,CNTFR,CPS1,CSF1,SEC14L5,EXOG,CDON,HIPK3,EIF4G2,DLC1,FGF12,INPP5K,GRB10,SPACA9,GRIK5,HLF,DHX35,KCNH2,SMAD1,MAP2,MGAT3,MPP2,MSI1,LRP12,PRKAR1B,ZNF821,ANKRD6,FAM214B,VPS13A,TNS1,KCNK12,SEMA3B,KCNAB1" Drug CID000022741 4-phenoxybutyric acid Stitch 1.90E-04 1.00E+00 2.35E-03 2.65E-02 4 4 "ABHD6,EDN1,EDNRA,EDNRB" Drug CID000128573 DMIPP Stitch 1.90E-04 1.00E+00 2.35E-03 2.65E-02 4 4 "KDM5D,AMH,INPP1,SMUG1" Drug DB00996 Gabapentin Drug Bank 1.90E-04 1.00E+00 2.35E-03 2.65E-02 4 4 "ADORA1,CACNA1B,CACNA2D1,CACNA2D2" Drug DB01303 Oxtriphylline Drug Bank 1.90E-04 1.00E+00 2.35E-03 2.65E-02 4 4 "ADORA1,ADORA2A,PDE3A,PDE4A" Drug CID000001678 3-nitropropionic acid Stitch 1.92E-04 1.00E+00 2.37E-03 2.67E-02 37 178 "ADORA1,ADORA2A,APAF1,KCNAB2,CACNA1A,CACNA1B,CALB1,SLC25A14,KYAT1,CNR1,HDAC9,DYNC1I1,PDCD6IP,FCF1,AASS,ENO2,PPP1R1B,PPARGC1A,TCERG1,GRIN2C,GRIN2D,PACSIN2,HP,IGF1,MAP2,OGG1,ABCB1,QDPR,FBXW7,ATXN7,FOXRED1,SNCA,JMJD6,PRTFDC1,SLC17A7,KCNAB1,JPH3" Drug 4582_DN "Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ABR,ADRA1D,AK2,C1QTNF1,APC,MARK4,STX16,CFLAR,SYNJ2,PLEKHB1,TPP1,ENTPD4,FAM131B,CDON,EDNRA,SCML2,PDLIM5,FAM49B,ZNF44,LSS,GIT1,PFKFB2,MAPK7,PRPH,SNRK,ATXN7,FNDC3A,ZBTB43,LHPP,POGZ,SS18,ELOVL4,PHLDB1,KIAA1107,SIN3B,DOCK9,TRIO,KLC2,MAP3K12" Drug 4614_UP Colchicine [64-86-8]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "AK2,LTBP4,DOC2A,CACNA1G,FOXN3,NRG2,AKAP12,DRP2,CALCRL,RASGRP2,PRELID3A,DOT1L,GNG4,FERMT2,SPACA9,IL6ST,KCNJ5,MIA2,AFF1,NEFM,PDE1C,RETREG1,NLE1,EMID1,FUZ,NLGN1,SLC11A1,SOX15,ZNF423,ARHGAP26,DDN,ATP10B,ELOVL4,PHLDB1,TRIO,UBE3A,VIPR2,WNT7A,NAV3" Drug 3387_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "AK2,BIN1,APBB2,APC,FAM131A,PPP4R4,RGS20,CFLAR,SYNJ2,GYG2,USP2,CRLF1,RCBTB2,WHRN,MFAP3L,DMPK,PLXNC1,SPEG,FGFR1,FHL1,SCARA3,CGREF1,OGA,SRCAP,PRKAR1B,PRODH,KCTD17,TCP11L1,RASA3,ASAP3,BTBD7,ZHX3,ELOVL4,DICER1,ZNF34,RUNDC3B,VIPR2,KLC2,REEP1" Drug 4487_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ADCY8,TRMT9B,ATP2B2,NRP2,RUNX1T1,CHRNA4,PCYT1B,ARHGEF10,VCAN,ARHGEF4,HDAC9,EDNRA,RASGRP2,DLC1,ST3GAL6,NSG1,FYB1,ZNF44,SIGLEC8,SPACA9,GRM8,AFDN,MYT1,MAPK7,PTPRB,PTX3,RASGRF1,KHDRBS2,TCP11L1,MRAS,ZNF415,TMCC1,SYT1,SYT5,TRIO,VIPR2,LMF1,KCNAB1,TIGD6" Drug 5957_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ALK,AMPD3,APBB2,DNAH17,CACNA1I,LHX2,TPP1,WHRN,NCOR2,AATK,ZNF804A,TMCC2,SLC12A6,FEM1B,IGSF6,DLC1,IQCG,KHDRBS3,TDRKH,GPER1,SPACA9,FICD,MPP2,MX1,PPP5C,RET,RGS12,KCTD17,RNASEL,TCP11L1,SNCA,DOP1A,SPTB,IQSEC2,PHLDB1,JMJD6,TACC1,TMEM121,EVI5" Drug 4273_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "MTUS1,PKP4,SYNJ2,CNTNAP2,GIT2,DBT,ZBTB24,SPOCK3,MBNL2,STX2,ANKFY1,DLL3,CRCP,RASSF8,AGFG1,IL6ST,MAP4,TM6SF1,PDE1C,PDE4A,CCSER2,PLCD1,STRN3,PRKAB2,PTN,SLC25A36,FBXW7,SEC14L1,FBXO11,ZNF667,COA1,SPTAN1,PBLD,SIK3,DICER1,CBX5,TMPO,ZNF24,MPPE1" Drug 4328_DN Lanatoside C [17575-22-3]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "AK2,C1QTNF1,AMT,APC,RGS20,CAMK2G,LRRFIP1,RAB26,ABI3BP,SMARCAL1,SLITRK5,DCAF4,SNPH,ARHGAP24,RHOBTB1,CHRDL1,FEM1B,ING4,MRNIP,ZNF589,FAM49B,BACH2,ITPKB,MIA2,THYN1,ZNF862,PDCD2,SAMD9,SNRK,SUPT20H,FAM214B,SPATA7,ASTN2,CABIN1,VIPR2,ZNF32,SPHK2,MAP3K12,SEMA3B" Drug 6837_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ADRA1D,AP2A2,SEMA6A,ALCAM,CDC42BPA,APC,CDC14B,CDK10,CFLAR,SYNJ2,CAMK2G,B4GALT6,ENTPD4,SOCS5,FAM169A,GREB1,RIMS2,TOM1,CNNM1,ZNF589,FGFR1,GAA,POLL,GNG4,JAK2,PCBP3,PTPN13,GSTCD,SLC9A5,COA1,SNCA,TTBK2,TRIM2,CRTC1,PARD3,PLPPR2,VAV1,GDPD5,EPM2A" Drug 1563_UP Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ARNTL,N4BP2L1,WASF1,KRIT1,CCNT1,HINFP,PPP1R16B,C2CD2L,DPYSL2,FGFR1,SEC23B,SMC2,ATP2C1,OGA,MALT1,DIDO1,KTN1,LAMP2,MAP4,MBD1,NINJ2,PRKACB,CNNM2,MSANTD2,SGK1,KBTBD4,ELMO2,ATF7IP,KDM3A,CDK19,PBLD,FBXW11,TCF4,CLASP1,CBX5,TST,EVI5,PDSS2,ST7" Drug 3574_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ABHD6,ARNTL,CDK13,ADGRB3,SYNJ2,CHRNA4,QKI,HOMER3,CNTFR,COL9A3,RGS6,ARHGEF10,PDE4DIP,RIPOR2,HIPK3,SPEG,ZNF589,GAD1,TMEM8B,MALT1,HMGCR,ADAM22,NF1,NFYA,CNOT4,NLE1,RETREG2,MINDY2,ZMAT4,KLHDC8A,RPS6KA2,S100B,CPEB3,TSNAXIP1,IQSEC2,PLCB1,WSCD1,RUNDC3B,SEMA3B" Drug 2840_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ALCAM,APBB2,APC,APOC1,CDC14B,CFLAR,GYG2,PICK1,CELSR3,NCALD,FGFR1,BAIAP2,HPCAL4,OGA,MSL3,SLC2A6,MID1,MITF,AFDN,ZNF862,NF1,NPY,NTRK2,MINDY2,PRKAR1B,PTN,SEC14L1,RASA3,COA1,SMARCD3,LIMCH1,UNC5B,JMJD6,PDLIM2,VGF,MKRN3,EVI5,ITM2C,MPPE1" Drug 448_UP trichostatin A; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ABHD6,ADD2,ARNTL,MARK4,CA12,HIP1R,PREPL,ABCG1,ARHGEF10,CTH,SNPH,DAPK3,PLPPR4,RGS17,TAOK3,BAIAP2,PDLIM5,FYN,STON1,GUCY1B1,VSIG4,AGFG1,LIFR,MAP2,TM6SF1,MEF2C,MMP17,RETREG1,SMOX,MBOAT7,ASAP3,SLA,ELMO2,UNC5B,ZC3H13,ARHGAP26,CDK19,CEP68,PLCB1" Drug 2466_DN "Azathymine, 6 [932-53-6]; Down 200; 31.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "PKP4,APAF1,KCNAB2,APC,STX16,CFLAR,CCNT1,SRSF11,EPS15L1,CLCN3,HOMER3,ARMC8,DBT,DTNA,FCF1,TUBD1,PDLIM5,CAMKK2,INPP5K,SPIN1,GLYR1,HTATSF1,TJAP1,NF1,NFYA,CNOT4,PRKAB2,GALNT10,SH3BP2,ZBTB43,TCF4,DICER1,SLC44A1,TMPO,KAT6B,TRPS1,FLRT2,NLRP3,SENP7" Drug 4451_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ADRA1D,TRMT9B,SLC2A11,BACH1,KSR1,BMP7,TPP1,NR1D2,CELSR3,ING4,ETV1,EFCAB2,GNG4,FERMT2,STON1,TJAP1,IL6ST,KCNF1,SMAD1,MMP16,LYRM9,PDE4B,SERPINI1,LRRN3,SNRK,CCDC40,RASGRF1,CCDC102B,SLC11A1,HECW1,ARHGAP26,CDK19,RBM26,CEP68,SZT2,DOCK9,TK2,ZNF225,SLC17A7" Drug 6399_DN C75; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.94E-04 1.00E+00 2.38E-03 2.69E-02 39 191 "ASIC1,ADCY6,ADORA2A,PKP4,APLP1,CDC14B,PDE8B,BCHE,RAB28,DAPK3,FECH,FGFR1,CGREF1,FYB1,DENND2A,ERAP1,SRCAP,PADI2,LAMA2,MMP16,CNOT4,NPR2,CLDN11,SMIM7,PID1,GAL3ST4,CSRNP3,ASAP3,SLC4A3,KBTBD4,ZNF667,TK2,CABIN1,TNS1,SMUG1,HIRA,PLPPR2,VGF,ZBTB14" Drug CID000004605 nsc25485 Stitch 1.95E-04 1.00E+00 2.40E-03 2.70E-02 57 312 "ADCY5,ADCY6,ADCY8,ADD1,SLC24A4,AGT,NT5C3B,ATP1A1,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B2,BLM,CA4,CA12,CACNA2D1,CALM1,CCK,CBFA2T2,ENTPD2,ASIC3,PLCXD3,BOC,SLC12A6,EDN1,EDN3,TMTC1,ATP2C1,FYN,PLCD4,TNFAIP8L3,HNMT,IGF1,LIG4,MATK,NBL1,ABCB1,PIK3C2A,PIK3R1,PKD1,PLCB2,PLCD1,PRKCB,MAPK3,MAPK4,MAPK7,DUSP15,SLA,SLC8A1,SLC9A5,SLC12A2,SLC14A1,PLCB1,NSD1,PIK3R5,SLC38A1" Drug 5246_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "SEMA6A,ALCAM,AMT,APC,NCOA1,ADAM15,SYNJ2,MTMR2,ARHGAP33,CLGN,TAOK2,QKI,ARHGEF4,EDNRA,EGFR,ING4,EPB41L2,STX2,BAIAP2,CINP,PDLIM5,INPP5K,SRCAP,GPER1,KCNH2,LMO2,MBOAT7,ZFHX4,CLIP1,EPN2,SLC6A8,LIMCH1,ZHX3,UHRF1BP1L,THSD1,PCDHA5,ZNF34,PLPPR2,VGF,MPPE1" Drug 1522_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,ADORA1,CDK13,MARK4,ATP1A3,SLC4A4,SYNJ2,SCAPER,CACNA1A,ARHGAP33,CACNA2D2,FOXN3,GREB1,DCAF4,DRP2,MBNL2,PLXNC1,EIF4G2,VPS13B,ERCC2,DLC1,MSL3,PRUNE2,TJAP1,GIT1,PLCD1,ZSCAN2,ZMAT4,EMID1,SLC11A1,BTBD7,SLC22A4,PEG10,SPART,VPS13A,TCF4,ZEB1,HIRA,VSNL1,EMSY" Drug 594_DN arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AK2,C1QTNF1,CDC42BPA,CACNA1I,C5,HAP1,VAX2,SH2B1,HINFP,MED12,PLEKHA1,STX2,TMEM8B,SRCAP,ZNF276,GRIK5,MAP4K5,PADI2,INPP5B,SMAD1,MMP17,MPP2,NOVA2,OPRL1,PCDH9,MASP1,RIPOR1,SEMA6D,ZNF821,SLC11A1,ELMO2,SMARCA4,TMCC1,KDM4B,ZSWIM8,TIAM1,ZKSCAN5,ZNF45,ZNF74,MPPE1" Drug 2173_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "PRX,USP2,KCNAB3,CPNE6,SEZ6L2,MBNL2,VPS13B,RASGRP2,STX2,ETV1,FHL1,FLT1,CAMKK2,GAA,FERMT2,MAP4,MAPT,MSR1,NINJ2,NOVA2,POU6F1,PPARA,CEP41,PKIA,RELN,PID1,RGS12,ZFHX4,FERMT1,CPEB3,IQSEC2,CLSTN2,SS18,TACR1,SIN3B,ZFPM2,KLC2,SLC17A7,KCNAB1,PHTF2" Drug 3258_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,FZD9,LTBP4,PPFIA3,RASL11B,CLGN,HOMER3,AKAP7,WHRN,RIMS2,ING4,ZNF589,FHL1,KHK,KITLG,GIT1,PALM,PGAM2,PLTP,PRKAR1B,PTN,CCDC40,C1orf54,RGS3,RXRA,ZNF821,SH3BP2,ARHGEF40,KDM4B,THSD1,ARC,SZT2,DOCK9,OBSL1,ZNF34,TNS1,TRIO,PLPPR2,WIPF1,SPHK2" Drug 4782_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMH,CDC42BPA,APBA2,KCNAB2,CDK10,PPP4R4,CFLAR,VAX2,AKAP6,COL9A3,SEC31B,RIMS2,DBN1,STX2,ZNF589,HPCAL4,AGAP2,GALC,GRB10,VSIG4,INPP1,KIT,MAPT,MEF2C,MSR1,NF1,NPTX2,NLE1,LRP12,MBOAT7,C1orf54,FBXW7,KCNIP1,ASAP3,TBCEL,IQCE,ZEB1,CRTC1,PCDHA6,GDPD5" Drug 368_DN WY-14643; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,SEMA4G,EIF4G3,ADAM23,DLGAP1,LHX2,CPS1,CRHBP,KLHL3,RCAN1,FAM13A,EGFR,PLEKHA1,CALCRL,ZMYND10,SCARA3,HPCAL4,NSG1,DENND2A,PCDH17,LILRA2,ADAMTS6,NXPH3,VSIG4,SYNPO,MMP16,ADAM22,SDK2,PPP2R2B,LRRN3,CEP41,RNASE1,SH3GL3,ST6GAL1,ZNF430,SLC11A1,SNAP25,SZT2,CDH22,TRPM2" Drug 4620_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,C1QTNF1,TRMT9B,PDE8B,ATP2B2,ADGRB2,BAIAP3,CFAP410,PLEKHB1,ABCG2,ARMC8,BRINP1,MFAP3L,DTNB,TOM1,HEYL,PLXNC1,AASS,ING4,MTSS1L,FGFR3,DENND2A,SIGLEC8,GCNT2,GFER,LYVE1,MSL3,CACFD1,MAP4K5,LIG4,MX1,CNOT4,ELOVL2,PTPRB,ASAP3,SMG6,THRA,TK2,TPM2,EVI5" Drug 6915_UP SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "PPFIA3,EIF4G3,SYNJ1,ST3GAL5,SRSF11,RAB28,QKI,CREM,HDAC4,SACS,EGR3,FYN,MALT1,TXNL4A,KCNH2,OPA1,OXTR,PTCH1,ELOVL2,PTPN13,PTPRG,KIF16B,FBXO11,WDR47,MAPKBP1,UHRF1BP1L,KDM4C,ELOVL4,NEK4,SYT1,MTCL1,TCF12,DOCK9,CRTC1,SSBP2,VGF,WRN,MFF,PCBP4,JMJD1C" Drug 3511_DN Roxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABR,NDRG3,ADD1,AK2,MARK4,KYAT1,VAX2,SH2B1,NCOR1,LRIG1,CSNK1E,PDE4DIP,MAML1,TOM1,SUGP2,EZH1,KAT8,FHL1,ANKFY1,TXNL4A,MAN1B1,INPP1,MAPT,MATK,MBD1,KITLG,FSD1,TMEM104,PTCH1,PTPRG,ZCWPW1,SUPT20H,SH3BP2,RBM34,STX1A,EXOC7,SATB2,CHST8,ZKSCAN5,ZBTB14" Drug 6929_DN 2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BRAP,OSBPL1A,STX16,BMP7,C5,SOCS5,PDE4DIP,GIT2,C2CD2L,DCTN4,FAM49B,SRCAP,CRCP,GRM8,BTN2A1,RNFT2,ATXN2L,HSF2,IPO5,MAP4,NCAM2,NPR2,SETD4,POLG,GTDC1,RGS3,ZFP30,FUZ,ZKSCAN3,ERC1,PBLD,TROVE2,ITPRID2,ANKRD12,SATB2,BEX4,TRIO,HIRA,XRCC4,MARCH8" Drug 1595_UP "Zidovudine, AZT [30516-87-1]; Up 200; 15uM; HL60; HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,BACH1,BMP7,CA12,CD86,AP4M1,RCBTB2,CNTFR,AKAP7,PCYT1B,SH2B1,PPP1R16B,DPH1,RCAN1,DCTN4,RASGRP2,OLFM1,CINP,ATP2C1,DIDO1,KCNN1,GIT1,PLCD1,STRN3,LRP12,MAPK10,CNNM2,PTN,RDX,RNASEL,ATXN7,MAPKBP1,ARHGAP26,LARP4,SIRT1,TSN,VIPR2,ZNF142,REEP1,EVI5" Drug 6160_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,PRX,ATP6V0A1,ADGRB1,CACNB4,CALB1,SOCS6,CREM,PDE4DIP,DZIP3,DGKG,SPOCK2,PLPPR4,DTNA,OPTN,ING4,RASGRP2,ERBB2,KAT8,AGAP2,TRAF3IP2,MSR1,MYO7A,NTRK2,DUSP26,PRPH,MASP1,FBXW7,HSPA4L,FERMT1,TMCC1,SPTAN1,IQSEC2,PHLDB1,TCF4,DMXL2,CRTC1,SH3GLB2,SLC17A7,KCNAB1" Drug 6257_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,NDRG2,ADCY6,SYNJ2,BAIAP3,CLDN10,SOCS6,FAM189A2,HAPLN1,CRY2,GREB1,GIT2,TOM1,EGFR,TNK2,COQ7,FGFR1,INPP5K,USP19,GRIK5,DHX35,IL6ST,KCNH2,TM6SF1,ZNF862,RETREG1,PILRA,CNNM2,WDR25,SYBU,BTBD7,SNCA,ZNF423,SPTAN1,ASTN2,OBSL1,ZNF34,CABIN1,FLRT2,HPS4" Drug 3883_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,NME5,BIN1,CDK13,SLC2A11,ARHGEF7,HIP1R,KYAT1,ARHGEF1,CBFA2T2,ARHGEF2,LHX2,USP6NL,DTNA,KAT8,SCARA3,DLL3,GCNT2,RUNDC3A,GPER1,ATXN2L,JAK2,KHK,MAP2,MMP17,ADAM22,PLCD1,CCDC40,SH3BP2,SMARCD3,ST5,PLCB1,CRTC1,SLC44A1,HEY1,FAM155A,VIPR2,KCNK12,FIP1L1,ITM2C" Drug 3197_UP Furosemide [54-31-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMPD3,OGT,CDC14B,ARHGDIG,PLA2G4C,ZSCAN18,CA4,CACNA1A,CBFA2T2,ASIC3,CHN2,B4GALT6,AKAP5,SUSD5,RASSF2,DAPK1,SPOCK2,HEPH,MFAP3L,RUSC2,DYNC1I1,DTNA,ECM2,FLNC,SIGLEC8,INPP5K,GPD2,TDRKH,GRIN2C,GSN,HLF,SYNPO,KPNA5,MAPT,MEF2C,PDE1C,PDE4A,PIK3R5,TPM2,ITM2C" Drug 6001_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG3,CDC42BPA,STX16,ADAM23,CACNA1I,ARHGAP33,B4GALT6,QKI,HOMER3,AKAP7,SH2B1,CDON,DTNA,ACSL4,ZNF589,FGFR1,GAD1,DISC1,TDRKH,IL6ST,IPO5,MAP4,NF1,CNOT4,CCSER2,TMEM104,RGS3,ASAP3,FAM214B,CXXC4,KDM4B,SPTAN1,IQSEC2,CAMTA2,ITPRID2,PHLDB1,ASTN2,IQCE,TBL1X,ZKSCAN5" Drug 3092_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,BRAP,AGT,FAM135A,APBB2,APOC1,PPP4R4,MTMR3,HIP1R,SCARB1,CREM,SIPA1L1,EXOG,HIPK3,TNK2,TUBD1,ERCC2,PTK2B,OLFM1,EFCAB2,ADAM28,LILRA2,KIFC3,LAMA2,LSS,SMAD1,MAP4,MEF2C,POLG,PTCH1,TCP11L1,SEC14L1,PPM1E,SNCA,TMCC1,KDM4B,ZNF34,R3HDM1,ZNF32,PRDM10" Drug 4278_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APC,EPB41L5,ATP1A3,ATP2B2,PROM1,CFAP410,RUNX1T1,CLDN10,FAM189A2,PICK1,NCOR2,CSF1R,MTSS1L,ETV1,REEP2,ST3GAL6,RUNDC3A,GRM2,PRDM5,SOX21,PADI2,KHK,MAN2A2,PCDHGC3,PDE4B,PDE4D,C19orf57,POU6F1,PRKAR1B,PRPH,PSD,ZSCAN32,PTPRB,KANSL3,MCF2L2,ARC,TRO,OSBP2,SLC30A4,DPF3" Drug 3479_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,AMT,KCNAB2,ARHGDIG,RCBTB2,GREB1,SNPH,MAML1,PLEKHA1,DENND4A,VPS26C,RRAGB,ZNF589,MSL3,DIDO1,MAP4,ZNF862,NNAT,NPR2,PCDH9,MTRF1L,GRAMD1C,PRPH,GTDC1,RGS4,RGS12,TCP11L1,ASAP3,PREX2,BTBD7,ZHX3,KDM4C,DIP2A,PLCB1,KIAA0930,PCDHA6,ZNF106,SLC44A1,FLRT2,ITM2C" Drug 3827_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,ADD2,ADGRF5,LTBP4,APAF1,PRX,ATP2B2,BMP7,CACNA1A,HAP1,CAMK2B,RUNX1T1,USP2,B4GALT6,CNTN1,EDIL3,EDNRA,ING4,IGSF6,ETV1,EZH1,EFCAB2,GLYR1,RAB30,SOX21,JAK2,KITLG,AFDN,NF1,RETREG1,NECAB2,POU6F1,WDR25,RASGRF1,ZMAT4,KIF13A,PLCB1,TAL1,TK2,XRCC4" Drug 2159_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,RIPK1,ADAM15,BMP7,C5,CFAP410,USP2,RAB33A,PLAA,ZNF337,DGKG,DTNB,E2F5,ING4,RASGRP2,PRKAG2,AFF2,ZNF44,SRCAP,GIT1,CCSER2,PLTP,POU6F1,MINDY2,PTCH1,ZNF821,SH3BP2,EPN2,FAM214B,SLC11A1,SNCA,IZUMO4,UNC5B,NSD1,CHST8,TNS1,TRPS1,LAMP5,GDPD5,PARP11" Drug 4214_UP Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,PPFIA3,N4BP2L1,KSR1,CACNA2D1,SCARB1,LARGE1,TAOK2,VAX2,HOMER3,NCOR2,CDON,PLXNC1,IRAK4,NCALD,IGSF6,CORO2B,PDLIM5,SRCAP,GFER,GLYR1,ICA1,KCNJ5,KIT,SMAD1,ADAM22,MSR1,NF1,PALM,PDE4B,RASGRF1,KCNIP1,SNCA,KIF13A,DOK5,ZHX3,IZUMO4,ZC3H13,PCDHA5,SLC17A7" Drug 3554_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,APC,ALDH7A1,RGS11,LDLRAD4,ARHGEF2,RCBTB2,EPS15L1,TPP1,ARHGEF6,SNCAIP,CNTNAP2,SEC14L5,SPOCK3,ERCC2,ST3GAL6,FGFR1,GAD1,DISC1,MSL3,SPACA9,ADAMTS13,ITPKA,KIFC3,NF1,PRODH,PTCH1,RGS12,CARF,ABLIM3,SLC11A1,SNCA,SPTAN1,ATP10B,PHLDB1,VPS13A,PLCB1,GPR161,ZFP37,SEMA3B" Drug 2246_DN Isoniazid [54-85-3]; Down 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,APC,BCAS1,CDK13,MARK4,CFAP410,CA4,ARHGAP33,HOMER3,AKAP7,ARMC8,ENTPD4,ARHGEF4,PPP6R2,TBC1D5,KAT8,ZNF589,GLYR1,GNG4,GPER1,GRB10,ICA1,ITPKB,LSS,MAP4,KITLG,NFYA,NPTX1,STRN3,TMEM104,ZDHHC14,ABLIM3,EPN2,SLC22A4,SMARCA4,CDK5RAP2,STX1A,EMSY,SEMA3B,UBE3B" Drug 5775_DN Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,CDK10,MARK4,SYNJ2,ENTPD6,CREM,HAPLN1,CSF1,CSF1R,DZIP3,C2CD2L,DENND4A,DENND2A,FERMT2,PRRC2B,GPR37,IL6ST,NF1,CNOT4,NPR2,CLDN11,NLE1,FSD1,MINDY2,PPP5C,MAPK7,PTPRE,PTPRH,NEK11,ZNF671,FBXO11,ELMO2,TROVE2,ELOVL4,CEP68,KIAA0930,HIRA,ZBTB14,EVI5,GAN" Drug 3104_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,SEMA4G,ARRB1,DNAH17,CLDN10,TAOK2,CREM,SLITRK5,SNPH,MFAP3L,SPOCK3,CNNM1,SPEG,DLC1,FGFR1,ERAP1,RUNDC3A,KCNJ5,MAP4,AFDN,N6AMT1,LYRM9,MYO6,NTRK2,PURG,POLG,PPP2R2B,PPP5C,CEP41,RFX2,TCP11L1,ZNF821,GALNT10,LIMS2,IQSEC2,EXOC7,TBCEL,SZT2,CHST8,XRCC4" Drug 7325_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG3,EPB41L5,APOC1,DNAH17,KIF1A,SYNJ1,CAMK2G,ARHGEF2,SOCS6,B4GALT6,ZFYVE16,TBC1D5,OPTN,STX2,FAM49B,PRELID3A,MALT1,GPR75,STON1,CNTRL,ELOVL5,HNMT,MAP4,KITLG,MPP2,PKIA,RIPOR1,RASGRF1,KCTD17,ZFHX4,ZNF821,CXXC4,RBM34,PLCB1,RPGRIP1L,DICER1,ZNF34,FAM155A,WIPF1,ZNF74" Drug 6925_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASPHD1,AP2A2,APBA2,GAS7,SEMA4G,CFLAR,ST3GAL5,ARHGEF1,VAX2,PDE4DIP,SNPH,GSDME,TMCC2,DTNA,FCF1,C3orf18,RASGRP2,RRAGB,INPP5K,SRCAP,GNG4,PRUNE2,MBD1,NOVA2,MAPK7,PTN,ZCWPW1,EMID1,TRAPPC13,TSNAXIP1,IQSEC2,SS18,STX1A,VPS13A,SYN2,EXOC7,WSCD1,TK2,REEP1,KCNAB1" Drug 3886_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMPD3,APC,PLA2G4C,CDK13,SYNJ2,GYG2,CA12,ARHGAP33,TAOK2,WHRN,NCOR2,CSF1,RIMS2,DNM1,EGFR,ING4,TNK2,HSD17B14,STX2,FGFR1,SRCAP,RUNDC3A,MAP2,MMP17,NF1,NPTX1,PLCD1,PRKCB,PTCH1,NKAIN1,RASA3,ST5,VPS13A,KIAA1107,TMEM121,SLC44A1,ZKSCAN5,ZNF74,SPHK2,MPPE1" Drug 2083_UP Isoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "DDO,SEMA4G,SLC4A4,MYRF,CCNT1,TPP1,ARMC8,COL9A3,DZIP3,FEM1B,FCF1,MBNL2,TUBD1,NCALD,TRMO,GPR37,PCLO,GUCY1B1,IFI16,SHISAL1,NFYA,PDE4B,PLXNB1,MAPK7,KHDRBS2,NUDT11,FBXW7,CLIP1,TSNAXIP1,IQSEC2,CAMTA2,PHLDB1,SYT1,DNAH7,THRA,HIRA,ZNF189,MAP3K12,KCNAB1,EPM2A" Drug 2529_DN Nadide [53-84-9]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,ANK2,KIF1A,MTMR3,CACNA1I,CACNA1A,FOXN3,PICK1,AKAP7,IQCK,CSF1,ARHGAP32,DAPK3,CDON,DPH1,EDNRB,MBNL2,EIF4G2,RASGRP2,F5,EFCAB2,GAA,ZNF44,TRAF3IP2,ERAP1,SEPT9,MAP4,MAPT,NF1,LRRN3,RGS3,TCP11L1,SLC11A1,BTBD7,SYN2,TAL1,FBXW11,THRA,FLRT2,SH3GLB2" Drug 7428_DN Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "FAM131A,APOC1,BCAS1,CDC14B,CFLAR,PLEKHB1,STOML1,HOMER3,AKAP7,PDE4DIP,MED12,DTNA,FEM1B,TNK2,KAT8,FGFR1,CGREF1,CSPG5,OGA,CNTRL,ATXN2L,LSS,MEIS2,NF1,PRKAR1B,TMEM104,TMEM231,FERMT1,ABLIM3,SLC6A8,SIRT2,ZKSCAN3,PHLDB1,MCF2L,PLPPR2,ZNF45,ZNF74,EMSY,KAT6A,GAN" Drug 7433_UP Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,AK2,SRPX,MARCH3,SLC4A4,ADAM15,MPDZ,SCAPER,GYG2,NRG2,AKAP12,DZIP3,NR1D2,DMTF1,HIPK3,MRNIP,VPS26C,GAD1,SYT17,INPP5K,GFER,MALT1,TXNL4A,RNFT2,INPP1,LIG4,MBOAT7,PRKCB,PRPH,SH3BGR,KANSL3,SLC6A8,CCDC88A,ATP10B,ANKRD12,EXOC7,CDK20,VLDLR,LMF1,RNF170" Drug 1897_UP Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APBB2,PPFIA3,SEMA4G,MARK4,CLCN3,AKAP7,BAG4,CDC42BPB,CREM,SOCS5,DAPK3,BRINP1,C2CD2L,ING4,C3orf18,ZNF589,OLFM1,PDLIM5,GLYR1,HTATSF1,SLC2A6,SHISAL1,IL6R,IL6ST,KTN1,MAP4,N6AMT1,GPSM2,ZSCAN32,C1orf109,STUM,KIF16B,CDK5RAP2,IQSEC2,DIP2A,CBX5,TSC2,UCHL1,LMF1,MAP3K12" Drug 3632_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "SYN3,ASIC1,PPFIA3,ARRB1,CACNA2D1,CALB2,CAMK2B,ABI3BP,CSF1,IPCEF1,RUSC2,CDON,DTNB,EDN1,ANKMY1,DLC1,INPP5B,KIF5A,ADAM22,NF1,NPR2,PFKFB2,PLXNB1,KHDRBS2,STUM,RASA3,SH3BP2,SH3GL3,SLC11A1,SNCA,WSCD1,PCDHGA10,GPR161,TNS1,CHST5,TRIO,UGT8,SPHK2,SLC30A3,KCNAB1" Drug 6079_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,APAF1,GAS7,ASPA,SLC2A11,CLTB,WHRN,NCOR2,SEC14L5,ELMO1,RASGRP2,APC2,FLNC,DLL3,OGA,FYB1,ZNF44,DISC1,SRCAP,LYVE1,SOX21,C2orf72,KCNH2,KCNN1,LAMA2,LIFR,MGAT3,P2RY1,PFKFB2,PPP5C,CEP41,PRKCB,RELN,SLC2A5,DOK5,CRTC1,TK2,R3HDM1,LAT2,ADAMTS9" Drug 1723_UP Bromperidol [10457-90-6]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADCY6,APC,ARNTL,ADAM15,AZGP1,WASF1,ENTPD6,TAOK2,AKAP7,OSBPL3,DOCK4,TM9SF4,C2CD2L,PCOLCE2,TUBD1,SH3YL1,KAT8,AGAP2,INPP5K,RUNDC3A,CACFD1,AGFG1,KCNN1,KIF5A,MYT1,PIK3R1,RETREG1,NLE1,MINDY2,PTX3,CLIP1,AMBRA1,BTBD3,MAPKBP1,TBL1X,MGRN1,PARD3,KAT6B,CHST5,ZNF142" Drug 2107_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMH,BAIAP3,CD86,CPS1,CSF1R,SNPH,ARMCX2,DTNA,TOM1,EIF4G2,STX2,SEMA4D,DLL3,SIGLEC8,STON1,GPR37,GRIK5,CACFD1,ADAMTS6,ELOVL5,MARK1,GIT1,CNOT4,PIK3R1,PPP5C,PRKAR1B,PTPRN2,GAL3ST4,ZFP30,ANKRD6,LIMS2,UNC5B,ZBTB43,ELOVL4,SYN2,TMEM121,CHST8,TLR4,CABIN1,TRIM9" Drug 3891_UP Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,NDRG2,ALCAM,NRP2,MTMR3,CACNA1I,CAMK2B,CH25H,ARHGAP33,TAOK2,CRMP1,TMCC2,CDON,EIF1,F5,FGFR3,AFF2,PDLIM5,CSPG5,GFER,PCDH17,GLYR1,GRIK5,MATN3,MEF2C,AFDN,MPP2,CLDN11,PNMA3,CEP41,SH3GL3,EPN2,KDM4B,PEG10,SPTAN1,ATP10B,WSCD1,TRPM2,PHTF2,ADAMTSL3" Drug 3198_DN Chlorthalidone [77-36-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADCY6,ADRA1D,AK2,TRMT9B,APBB2,RASL11B,SLC4A4,KIF1A,SOCS6,SH2B1,CSF1R,FAM169A,CYBB,DTNA,EDNRA,EIF5,FGFR1,FHL1,ANKFY1,GABRG2,ERAP1,MSL3,HNMT,IL6R,ITPKB,MINDY2,RELN,RAD51D,RGS12,GSTCD,RPS6KA2,RASA3,COA1,KIF13A,DOCK9,SLC44A1,PARD3,RUNDC3B,ZNF74,EPM2A" Drug 5392_DN Metolazone [17560-51-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "RALGAPA1,AP2A2,C1QTNF3,APLP1,CDC14B,ARHGDIG,ALDH7A1,SYNJ2,KYAT1,B4GALT6,SLIT2,AKAP7,SH2B1,JAKMIP2,CNNM1,ACSL4,FGFR1,CGREF1,OGA,SEPT9,RUNDC3A,GNG4,INPP5B,MGAT3,MPP2,NEK1,NPR2,NLE1,PRKAR1B,PRODH,ZDHHC14,RGS12,KDM4B,PHLDB1,MCF2L,CHST8,BHLHB9,TPM1,CLDND1,ZNF45" Drug 5727_UP Dienestrol [84-17-3]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NRP2,SYNJ1,KALRN,CAMK2B,NRXN3,HOMER3,WHRN,SPOCK3,PLXNC1,IGSF6,ZNF549,NRN1,FGF1,EFCAB2,ERAP1,SIGLEC8,ALDH1L1,SRCAP,GNG4,PADI2,KCNJ5,MEF2C,MN1,TAGLN3,LYRM9,MYO7A,NF1,CNOT4,ACSS3,ENOX1,RFX2,SMPD3,ZNF821,FNDC3A,RBM34,SPTAN1,TACR1,TCF4,FLRT2,ZBTB14" Drug 6625_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADORA1,MTUS1,ALK,EPB41L5,ADAM23,SYNJ1,ARHGAP33,CACNA2D2,ENTPD4,PDE4DIP,CNTNAP2,PPP1R16B,C2CD2L,RASGRP2,ABCA8,DCTN2,ALDH1L1,PCDH17,PADI2,MAN2A2,NELL2,CNOT4,NTRK3,PCDH9,PDE4A,PDE4B,MAPK10,C1orf54,EMID1,ASAP3,OGDHL,KIF13A,SP4,HECW1,SPTAN1,ZEB1,RUNDC3B,FLRT2,LAT2,KCNK12" Drug 5514_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,ABHD6,AMH,APBB2,CDK10,ARHGDIG,ADGRB1,SGCE,CA4,EPS15L1,SH2B1,CSF1R,CNTNAP2,SNPH,DCAF8,C3orf18,ETV1,NRN1,OGA,ATXN2L,HNMT,IRF8,KHK,IPO5,NFYA,SERPINI1,SLC25A23,PPP5C,MARCH1,SALL1,CNKSR2,ARHGEF40,SS18,CEP68,ZEB1,PCDHA6,UCHL1,XRCC4,SLC30A3,KCNAB1" Drug 3381_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADD2,KCNAB2,ATP1A3,CFLAR,KSR1,CDO1,RAB33A,AKAP6,CSF1,MFAP3L,ERCC2,REEP2,FGFR3,SIGLEC8,ADAM28,GRB10,GRIK5,GSN,HLF,LAMA2,ADAM11,OPRL1,LRRN3,CEP41,MAPK7,VPS13C,ZMAT4,PNMA8A,EMID1,ST6GAL1,KDM4B,ARC,WSCD1,CABIN1,PIK3R5,UCHL1,LAT2,SLC30A3,SLC17A7,PHTF2" Drug 4621_DN Niridazole [61-57-4]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MADD,PDE8B,CAMK2B,SYNGR3,TAOK2,ABCG2,SLC4A8,VCAN,FAM131B,DBT,EGFR,MRNIP,ERCC2,FGFR1,AFF2,ZNF44,SEPT9,MSL3,GPR37,CACFD1,IFI16,MGAT3,MX1,NEK1,PTN,ZSCAN32,FAT4,FBXW7,AP1AR,ASAP3,CCDC88A,TMCC1,TSNAXIP1,SPTAN1,ARHGEF9,SMG6,EVI5,SEMA3B,ST7,SMIM8" Drug 7076_UP PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APBA2,APBB2,ALDH7A1,SOCS6,CLCN3,OSBPL3,USP6NL,FAM131B,DCAF8,SGSM2,CNNM1,BAIAP2,CSPG5,ERAP1,DISC1,INPP5K,GPER1,MIA2,SLC11A2,OGG1,POLG,PTPRE,ZDHHC14,MRPS18A,ZNF671,MCMBP,SAFB,SBF1,ZFP30,DZIP1,SLC6A8,SMARCD3,SEPT8,PHLDB1,TCF4,SZT2,CABIN1,METTL3,NPDC1,UPF3A" Drug 208_UP SC-58125; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BRAP,CDC42BPA,APAF1,CACNA1I,HAP1,CCNT1,CBFA2T2,ARHGAP33,FOXN3,AKAP12,NCOR2,SPOCK2,ING4,SMC2,CSPG5,MALT1,GLYR1,C2orf72,IL6ST,KCNJ5,KIF2A,ADAM22,SETD4,OPRL1,PDE1C,GPR173,PLEC,PMP22,MAPK3,PRPH,RIPOR1,C1orf54,SAFB,KBTBD4,ELMO2,SYT5,PCDHA5,ZKSCAN5,MAP3K12,MPPE1" Drug 4958_DN Theobromine [83-67-0]; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BRAP,AMT,NUMB,CFLAR,C5,CCNT1,CBFA2T2,QKI,AKAP7,NECTIN3,ENTPD4,DZIP3,ARMCX2,E2F5,RGS17,ANKMY1,PRELID3A,SRCAP,MALT1,GRB10,CACFD1,MAPT,ZNF862,NEK1,NFYA,PCDH9,SLC25A23,PRODH,TMEM104,ZDHHC14,ZNF331,SAFB,ZNF821,PEX26,EPN2,VLDLR,REEP1,EVI5,HPS4,ST7" Drug 4986_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADORA2A,ADRA1D,ALCAM,BIN1,AMT,APC,APOC1,BCAS1,CDC14B,PLA2G4C,ARMC8,CNTNAP2,TBC1D5,DAPK3,C2CD2L,DTNA,SCML2,DLC1,GPD2,TDRKH,GRB10,MSI1,N6AMT1,NEK1,NPR2,PLCD1,PLXNB1,MBOAT7,ZDHHC14,GSTCD,ASAP3,LIMCH1,ZHX3,TSPYL2,NXT2,TK2,FAM155A,VLDLR,ZNF24,PHTF2" Drug 3201_UP Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NME5,APLP1,DDO,ARHGDIG,PTCH2,NRP2,BAIAP3,CBFA2T2,ARHGAP33,B4GALT6,AKAP5,NCOR2,HDAC4,DAPK3,ING4,ACSL4,FGF1,AGAP2,NEU3,GLYR1,HAS2,JAK2,KPNA5,MYO7A,NEFM,PLTP,PPP1R1A,GDPD2,SCN2B,ASAP3,SLA,SLC6A8,SLC9A5,SYN2,PCDHGB6,CRTC1,AMACR,XRCC4,SEMA3B,SLC17A7" Drug 1412_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; HL60; HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,C1QTNF1,C1QTNF3,APOC1,ARNTL,CACNA1I,CAST,CBFA2T2,LRBA,FOXN3,RAB28,FAM189A2,TMEM184B,BAG4,DAPK3,CD320,ANKFY1,GAA,PADI2,MAN1B1,SMIM7,PLTP,POLG,PTH1R,PTN,CRTAC1,TCP11L1,ZNF821,ELMO2,INTS9,MAPKBP1,KDM4B,UNC5B,LMO3,TCF4,CRTC1,CHST5,VGF,XRCC4,ADAMTS9" Drug 3612_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "SPARCL1,APC,AQP6,MARK4,PTCH2,ATP2B2,ST3GAL5,GYG2,CDH2,RCBTB2,CSF1,VCAN,RIMS2,HS3ST2,EDN1,ETV1,AFF2,FOLR2,NSG1,GRM8,ITGA7,KCNN1,KIF5A,MEF2C,MGAT3,ZNF862,NPR2,NECAB2,CEP41,ELOVL2,C1orf54,RNASE1,RXRA,MYH15,SNAP25,PEG10,SYN2,SLC44A1,MKRN3,SPHK2" Drug 5473_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,ALK,BIN1,SEMA7A,ALDH7A1,BAIAP3,SULT4A1,SPOCK3,CDON,HIPK3,C3orf18,MTSS1L,STX2,ABCA8,FGFR1,HPGDS,HLF,IL6ST,KCNJ5,MMP16,GIT1,ADAM22,P2RY1,DUSP26,SERPINI1,GDPD2,ACSM5,C1orf54,RYR3,FRMPD1,NLGN1,ABLIM3,SLA,CLSTN2,RPGRIP1L,GPR161,TK2,R3HDM1,LMF1,EPM2A" Drug 5524_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "GAS7,CDC14B,PLA2G4C,PTCH2,CFAP410,USP2,CBFA2T2,RAB33A,QKI,LRIG1,VCAN,GPRASP1,DAPK3,EDNRA,MTSS1L,NCALD,NRN1,TPK1,DHX35,ICA1,IGF1,MSR1,CNOT4,STRN3,NECAB2,ELOVL2,CCDC40,CNKSR2,PKNOX2,KIF13A,HECW1,IQSEC2,VPS13A,SYN2,SMG6,OBSL1,TK2,R3HDM1,KCNK12,HPS4" Drug 4790_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,BIN1,CFLAR,SYNJ2,MTMR2,SOCS6,CREM,SIPA1L1,PDE4DIP,GIT2,DTNA,EDNRA,FECH,NOP56,INPP5K,TXNL4A,GPD2,JAK2,KIF2A,IPO5,MIA2,MITF,NFYA,PDCD2,PLXNB1,LRP12,PRODH,TMEM104,WDR25,PTCH1,ZNF430,INTS9,SPATA7,TSPYL2,SATB2,CABIN1,RUNDC3B,ZKSCAN5,XRCC4,PCBP4" Drug 3402_DN Primidone [125-33-7]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,LTBP4,AMPD3,BIN1,APBA2,APLP1,SYNJ2,SLC16A4,CLGN,WHRN,SH2B1,NCOR2,SGSM2,DMPK,EDNRA,EIF4G2,ING4,ELN,SPEG,ZNF589,PDLIM5,SRCAP,ELOVL5,KCNH2,KHK,MAPT,MMP16,PALM,MINDY2,PPP5C,MAPK10,EMID1,PEX26,SNCA,IQSEC2,SPART,THSD1,PLCB1,SMG6,REEP1" Drug 6816_DN Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,ARHGDIG,ATP6V0A1,CFLAR,ARHGEF7,KRIT1,SYNGR3,LRRFIP1,TAOK2,NCOR1,ABCG1,CSNK1E,SOCS5,RIMS2,DCAF8,ZNF337,DTNA,EDNRA,FEM1B,PHF20L1,STX2,EZH1,F8,ZNF589,MAN1B1,KCNH2,LRP12,PPP5C,ZCWPW1,RBBP6,RGS12,NEK11,RPS6KA2,SBF1,SH3BP2,ZHX3,ELOVL4,LMF1,TFIP11,EVI5" Drug 7383_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "RALGAPA1,ADCY6,PPFIA4,PICK1,PDE4DIP,EXOG,CNNM1,ETV1,FGF13,FLT1,FYB1,SIGLEC8,ZNF276,GLYR1,TJAP1,FAM69A,ITPKA,MAPT,MX1,NELL2,CLDN11,RIPOR1,TMEM231,SH3TC2,FAT4,GAL3ST4,RGS12,NEK11,FBXW7,FRMPD1,RBM34,UNC5B,SPTAN1,ST5,ASTN2,TMEM121,BEX4,CABIN1,REEP1,UBE3B" Drug 2945_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "FAM131A,PDE8B,KIF1A,HAP1,HIP1R,ARHGAP33,TAOK2,SLIT2,ABCG1,SPOCK2,MFAP3L,TNK2,FER,BAIAP2,ALDH1L1,STON1,PADI2,TJAP1,LAMA2,ADAM22,NRCAM,PCDH9,PDE1B,PDPK1,NECAB2,ZCWPW1,ZFHX4,TCP11L1,SEC14L1,SLC6A8,SLC11A1,MYH15,ZHX3,SPTAN1,LHPP,ZNF34,TNS1,KCNE5,GDPD5,FZD3" Drug 4717_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,ALK,SYT13,LGR5,PDE8B,SCAPER,QKI,FAM149A,CREM,SPOCK2,GIT2,EZH1,FGF12,KHDRBS3,GAD1,GCNT2,RUNDC3A,TDRKH,CACFD1,GRM8,HLF,MEF2C,MID1,NEFM,PDE4B,GPR85,STRN3,PPP5C,ELOVL2,C1orf54,RBBP6,SYBU,NLGN1,DZIP1,SNCA,ZC3H13,PLCB1,SYT5,PCDHA6,OSBP2" Drug 7296_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASPHD1,CDC42BPA,CDK10,PPP4R4,MARK4,SCARB1,CACNA2D2,CHN2,RAB26,HDAC9,MFAP3L,RUSC2,EDNRB,COQ7,RRAGB,EZH1,IQCG,TRMO,FYB1,GPER1,ELOVL5,IL6ST,LIG4,MGAT3,MYCN,NOVA1,CCSER2,SLC25A23,TMEM231,SCN8A,AMBRA1,ST6GAL1,PPP4R3A,TMCC1,DDN,EXOC7,ZEB1,DOCK9,ZFPM2,CABIN1" Drug 7334_DN Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,CDC42BPA,APC,APOC1,PPFIA3,BMP7,DTNA,FEM1B,SUGP2,ENO2,CDKL3,ANKFY1,GALC,SYT17,INPP5K,ZNF276,PRRC2B,DHX35,INPP5B,ITPKB,MAP4,MAPT,MATK,KITLG,KCTD15,LRP12,GSTCD,ATXN7,FUZ,TSPYL2,CLASP2,STX1A,IQCE,SZT2,KAT6B,CABIN1,KCNAB1,MPPE1,SMIM8,RNF170" Drug 5425_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,PPP4R4,PLA2G4C,HAP1,CAMK2G,CD38,MYRIP,ARHGEF4,SEC14L5,DMPK,SHANK1,HIPK3,SEMA3D,RCAN2,MTSS1L,HPCAL4,FUT9,SIGLEC8,SRCAP,LPAR4,SPACA9,TJAP1,KCNB1,KCNQ3,MAP4,MMP17,ADAM22,PDE4A,MAPK7,C1orf54,FBXW7,EMID1,ST8SIA1,SLC9A5,SLC11A1,LIMCH1,SPTAN1,ATP10B,KCNAB1,PLSCR4" Drug 3325_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BRAP,BIN1,RGS11,CACNA1I,CFAP410,RUNX1T1,CHN2,AKAP7,NECTIN3,SNCAIP,HIPK3,FHL1,HPCAL4,LYVE1,RUNDC3A,GNAL,GPER1,GRM8,ICA1,TJAP1,KCNN1,MMP16,NEK1,NF1,SLC11A2,PAX6,PCDH9,STRN3,LRP12,SAMD9,ZMAT4,RGS4,ZNF821,FRMPD1,LIMCH1,DOK5,ARHGAP26,ANKRD12,WSCD1,KCNAB1" Drug 5464_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NME5,KCNAB2,PPP4R4,ARHGDIG,ARHGEF1,ARHGAP33,RCBTB2,SULT4A1,VCAN,GIT2,JAKMIP2,KIAA0753,DUSP9,PLXNC1,ACSL4,TPK1,DISC1,GATM,RUNDC3A,GSN,HNMT,TJAP1,KCNH2,LIG4,C1orf54,ZNF493,RGS4,TCP11L1,RPS6KA2,ZNF821,COA1,SNCA,FAIM2,TACR1,MCF2L,SMG6,KIAA0930,DOCK9,PIK3R5,CLDND1" Drug 4074_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ALDH7A1,HOMER3,CPS1,CREM,VCAN,GPRASP1,CHRDL1,DYNC1I1,SEZ6L2,EDNRA,FGF13,ZNF44,GAD1,DISC1,INPP5K,ZNF276,TDRKH,SHISAL1,RBPJ,MAPT,MPP2,NOVA1,PIK3R1,SLC25A23,LRP12,MAPK7,RIPOR1,TRAPPC13,FNDC3A,PPP4R3A,KBTBD4,SS18,ZEB1,TK2,TNS1,OSBP2,LMF1,XRCC4,ZNF45,NAV3" Drug 3756_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "PKP4,APAF1,KCNAB2,FUBP1,CFAP410,CACNA1A,CAMK2B,SYNGR3,LRIG1,ARHGAP24,DTNA,NCALD,OLFM1,FGF12,BAIAP2,HPCAL4,GALC,GNG4,GRM8,PADI2,IRF8,KCNH2,KCNQ3,NPTX1,NPTX2,NRCAM,PCDHGC3,PCSK5,PRKCB,PTN,PTPRH,PBRM1,CSRNP3,CNKSR2,PREX2,ARHGEF40,COBL,AP4E1,CA14,JPH3" Drug 6797_UP Aconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMT,KCNAB2,CA4,CDH2,AKAP6,PDE4DIP,JAKMIP2,ELMO1,HEYL,MRNIP,HSD17B14,VPS13B,FHL1,PDLIM5,GFER,GNAL,TDRKH,NXPH3,ICA1,KCNJ5,LAMA2,NF1,MINDY2,LRRN3,MAPK7,MASP1,ZNF493,ASAP3,SLC11A1,BTBD7,ZC3H13,TROVE2,EXOC7,PCDHGA10,TK2,RUNDC3B,FAM155A,LMF1,ZNF24,KCNAB1" Drug 5435_UP Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,APBA2,GAS7,SEMA4G,RASL11B,ATP2B2,RGS11,ST3GAL5,LDLRAD4,HIP1R,STOML1,CPS1,SPOCK2,JAKMIP2,DUSP9,HIPK3,AFF2,GRIK5,SHISAL1,KCNB1,KCND2,KCNQ3,MBP,PDE4D,PILRA,WDR25,MTMR10,RGS12,SALL1,FAM214B,HECW1,IQSEC2,TCF4,TNS2,CRTC1,ICAM5,TRIO,KCNAB1,ITM2C,TIGD6" Drug 4397_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,NDRG2,ATP2B2,SCAPER,CFAP410,CACNA2D1,RHBDL1,CD86,DGKI,TAOK2,NCOR2,ARHGEF10,CNTNAP2,ETV1,F5,OLFM1,GAD1,SRCAP,HAS2,ADAM22,NPTX2,OPRL1,PCDH9,STRN3,PPARA,FAT4,ZMAT4,SH3GL3,SLC2A5,KANSL3,SLC11A1,PEG10,TAL1,WSCD1,SLC35G2,ICAM5,LAT2,ITM2C,PLSCR4,AP3B2" Drug 6473_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADORA2A,AP2A2,BIN1,CDC42BPA,APC,EPB41L5,FAM131A,CDC14B,CDK10,ADAM15,CACNA1I,LDLRAD4,LHX2,SH2B1,CNTNAP2,ZNF337,DTNA,EDNRA,PLXNC1,COQ7,OGA,GNG4,DIDO1,CACFD1,IDH3A,KCNF1,KCNH2,MMP16,NELL2,NF1,P2RY1,MINDY2,PTN,ZCWPW1,FBXW7,DOK5,TRIM2,PLPPR2,HPS4,SEMA3B" Drug 3393_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ALCAM,TRMT9B,AMPD3,PRX,LDLRAD4,CA4,CAMK2G,RHBDL1,CCNT1,ARHGEF2,SNCAIP,ARHGEF10,CDON,DTNA,ERBB2,ERCC2,NRN1,FHL1,EFCAB2,CAMKK2,FYB1,C2orf72,ITGA7,KIF5A,KITLG,ADAM22,MX1,PALM,ZMAT4,KLHDC8A,CARF,SH3GL3,ARC,SYN2,RPGRIP1L,CRTC1,UBE3A,CLIP2,LAT2,PHTF2" Drug 5861_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "C1QTNF1,DOC2A,APC,CDK13,RGS9,CLDN10,CRLF1,CNTN1,AKAP6,CSF1R,PDE4DIP,EDIL3,TENM1,VPS26C,CORO2B,FCGRT,DISC1,GFRA2,MSL3,PRUNE2,LPAR4,SCIN,KCNF1,NF1,NNAT,PPP1R1A,PRKAR1B,MAPK10,PTPRN2,SLC4A3,KIF13A,DOK5,ARHGAP26,ASTN2,TACR1,FAM189A1,CRTC1,WIPF1,LAT2,SLC17A7" Drug 7190_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "FAM131A,CFLAR,SCAPER,CAMK2G,ARHGEF2,SOCS6,RAB28,FAM189A2,QKI,ZNF337,MFAP3L,HIPK3,MBNL2,COQ7,BAIAP2,SEMA4D,ANKFY1,PDLIM5,DLL3,SRCAP,RUNDC3A,GLYR1,GRB10,IL6ST,INPP1,MAPT,TAGLN3,PDE4D,MINDY2,PRPH,SYBU,PPP4R3A,SLC22A4,ZKSCAN3,SS18,EXOC7,PCDHA6,THRA,ZNF45,EVI5" Drug 2815_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "DNAH17,SLC4A4,CACNA2D2,RCBTB2,CHN2,TAOK2,ARHGEF6,NECTIN3,SH2B1,CRMP1,SGSM2,TNK2,STX2,ZNF589,OGA,TJAP1,KCNF1,MAP4,ADAM22,CLDN11,PCDH9,CDK18,PLCD1,PRODH,RELN,PTN,EMID1,SH3BP2,SH3GL3,ZBTB43,ST5,ARC,KIAA1107,WSCD1,PCDHA5,CABIN1,PLPPR2,DNALI1,SEMA3B,ITM2C" Drug 5592_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ACTN1,DOC2A,AMH,GAS7,ARRB1,RASL11B,ADGRB1,CFLAR,CA4,CLDN10,CBFA2T2,CLGN,NCOR2,ING4,FHL1,RUNDC3A,GRM8,TJAP1,IL6R,MAP2,MID1,ADAM22,NF1,TMOD2,KCTD15,PLCB2,LRP12,KCTD17,CPEB3,SLC9A5,KDM4B,SS18,PLCB1,TAL1,DMXL2,TRIM2,CHST5,VIPR2,LAT2,XRCC4" Drug 2149_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,APC,GAS7,CDK13,NCOA1,SYNJ2,CAMK2G,ARHGAP33,ZNF337,DGKG,EXOG,RASGRP2,AFF2,TRAF3IP2,INPP5K,CRCP,POLL,KCNJ5,MIA2,GIT1,MX1,NF1,SLC11A2,PMP22,RGS3,SH3BP2,BTBD7,ARFGAP1,KDM4B,FNBP1,DOK5,IZUMO4,DBNDD2,NSFL1C,KIAA1107,NSD1,PARD3,TNS1,ZBTB14,ZBTB38" Drug 4750_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,AMPD3,GAS7,PLA2G4C,MARK4,SLC2A11,ALDH7A1,SLC25A14,CLGN,PLEKHB1,HOMER3,CREM,CTH,GREB1,SLC12A6,EDNRA,NCALD,DLC1,ST3GAL6,AFF2,SRCAP,GNG4,PCLO,ATXN2L,JAK2,MEF2C,MPP2,NEK1,NNAT,STRN3,LRP12,MAPK7,SBF1,ZNF821,FAM214B,RBM34,ZC3H13,CLSTN2,CEP68,ZNF711" Drug 2730_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADRA1D,DOC2A,BIN1,NUMB,SCAPER,LDLRAD4,EPS15L1,NRG2,NCOR1,CSF1R,DCAF8,MFAP3L,DTNA,MTSS1L,KAT8,INPP5K,SRCAP,GPR75,POLL,LSS,SMAD1,MYT1,NNAT,CCSER2,POU6F1,TMEM104,FAM184A,ZFHX4,SLC12A2,TMCC1,KDM4B,DOP1A,ARHGAP26,TROVE2,OBSL1,R3HDM1,UBTF,CLIP2,MAP3K12,TIGD6" Drug 3045_DN Hymecromone [90-33-5]; Down 200; 22.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AMPH,BIN1,APBB2,MARK4,ATP2B2,NRP2,HIP1R,CLGN,EPS15L1,PLAA,NCOR2,B3GAT3,F5,FHL1,EFCAB2,KHDRBS3,INPP5K,AHDC1,LILRA2,AP4S1,SLC2A6,ATXN2L,ELOVL5,TJAP1,KCNJ5,MAP4,PDE4D,RETREG1,MTRF1L,PTCH1,ZSCAN32,NEK11,ZNF821,FAM102A,SNCA,ZNF415,TSPYL2,IQCE,PCDHGA10,TPM2" Drug 3847_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,ARHGDIG,CFLAR,SYNJ2,GYG2,BAIAP3,CA12,CNTNAP2,DZIP3,C2CD2L,DUSP9,EDNRA,ING4,ELN,HSD17B14,FGFR1,BAIAP2,AHDC1,GFER,MALT1,MIA2,ADAM22,NTRK2,PLCD1,PRPH,ENOX1,ZMAT4,EMID1,SEC14L1,SNCA,UNC5B,SPTAN1,ST5,CRTC1,VIPR2,LMF1,LAT2,KCNK12,ZFP37,ST7" Drug 1235_DN genistein; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NME5,MTMR2,CA12,QKI,HOMER3,ABI3BP,CNTNAP2,LYPD1,PARD6A,MED12,FEM1B,SPEG,DLC1,CHST15,FGFR1,TRMO,CGREF1,SYNPO,KHK,MEF2C,SCAMP5,NDP,CNOT4,PTPRN2,ZDHHC14,RGS4,CSRNP3,ASAP3,AMBRA1,ARFGAP1,LIMCH1,PDZD2,SPTAN1,SPART,METTL3,TRIO,TSC2,SSBP2,TRIM9,SENP7" Drug 6797_DN Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASPHD1,ADRA1D,AP2A2,ALCAM,PPFIA3,SCAPER,PLEKHB1,SLIT2,LHX2,TPP1,SLC4A8,AKAP12,ARHGEF10,PDE4DIP,FAM169A,MFAP3L,ING4,FER,PDLIM5,CGREF1,HTATSF1,POLL,AGBL5,KHK,LSS,SLC11A2,PCDH9,SLC25A23,ELOVL2,GTDC1,SH3BP2,ARHGAP26,THSD1,TTBK2,PHLDB1,PLCB1,EXOC7,TRIM2,KAT6B,NDRG4" Drug 2556_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "C1QTNF1,AMH,BIN1,ANK2,APOC1,KSR1,BMP7,MYRF,CDH2,ASIC3,CRMP1,F5,PTK2B,FGF12,NBEA,CAMKK2,ADAM28,ZNF276,PADI2,TJAP1,KCNN1,MSR1,TAGLN3,NF1,NRCAM,PLCD1,FSD1,MAPK10,CNNM2,ZFHX4,RASA3,SYBU,DOP1A,IZUMO4,TACR1,KIAA1107,ICAM5,PARD3,TRPS1,ZBTB38" Drug 5512_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABR,NDRG2,AGT,CDK10,SPTBN4,PLA2G4C,SCAPER,MTMR3,CLGN,QKI,AKAP7,SNCAIP,CSF1R,RGS6,SIPA1L1,SEC14L5,HSD17B14,CORO2B,FGFR1,TPK1,GPR162,RUNDC3A,ACOT7,HNMT,INPP5B,ADAM22,NOVA2,NLGN3,SLC25A23,STRN3,PRKCB,DIRAS2,GTDC1,RPS6KA2,UNC5B,MCF2L,WSCD1,TK2,FLRT2,KCNAB1" Drug 5615_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "FZD9,GAS7,ARHGDIG,AZGP1,KALRN,HAP1,HIP1R,EPS15L1,PICK1,WHRN,CRMP1,HAPLN1,VCAN,CNTNAP2,SPOCK2,PLXNC1,SPEG,REEP2,FYB1,ERAP1,PRUNE2,KCNH2,KCNJ5,KHK,ADAM22,NF1,PFKFB2,MAPK10,MASP1,SNRK,TRIM68,SEMA6D,CPEB3,SLC11A1,SNCA,ZSWIM8,PHLDB1,GPR161,UCHL1,DNALI1" Drug 1797_DN Trichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADGRF5,APC,APOC1,MARK4,ST3GAL5,PLEKHB1,EPS15L1,CSF1,GIT2,EIF5,TNK2,SCML2,SCARA3,PDLIM5,FAM49B,INPP5K,ZNF276,GLUL,GPER1,MUM1,FAM69A,KHK,SMAD1,MX1,ZNF862,NFYA,PFKFB2,PLEC,SLC25A23,MBOAT7,RGS4,ELMO2,CDK19,SS18,DNMBP,IQCE,KAT6B,FAM155A,UPF3A,SMIM8" Drug 1868_DN Dapsone [80-08-0]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABR,BRAP,ARRB1,MARK4,SYNJ2,SLC25A14,SOCS6,TPP1,CLOCK,OSBPL3,DZIP3,ZNF337,EPB41L2,VPS26C,FECH,ERAP1,MAP4,ZNF862,NINJ2,SLC11A2,SETD4,GPR85,MINDY2,SNRK,TMEM231,ZC3H14,HSPA4L,FBXO11,SPTAN1,CDK19,ZBTB43,KANK1,STXBP1,TCF4,TK2,ZKSCAN5,UPF3A,GDPD5,UBE3B,ACTR3B" Drug 2387_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,BEGAIN,BIN1,CDC42BPA,APAF1,APC,NCOA1,KSR1,BMP7,SYNJ1,CACNA2D1,CD38,CHN2,HOMER3,COL4A5,PPP1R16B,EIF4G2,RASGRP2,CDKL3,FHL1,TJAP1,IL6R,KCNF1,MAPT,NFYA,PLEC,PTK2,ASAP3,PEX26,EPN2,SOX15,THSD1,SS18,PLCB1,PDLIM2,TBL1X,RPGRIP1L,CRTC1,FLRT2,LAT2" Drug 2890_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADD2,APAF1,APBB2,APOC1,NRP2,CFLAR,CACNA1I,CAMK2B,HIP1R,SLC16A4,WHRN,VCAN,SPOCK2,ZNF804A,DMPK,CDON,FRY,MBNL2,C3orf18,APC2,ANKMY1,ALDH1L1,RUNDC3A,ITPKA,NF1,P2RY1,PDE4B,PPARA,RELN,CRTAC1,RGS12,SLC8A1,IQSEC2,CRTC1,TMEM121,FAM155A,UGT8,OSBP2,FLRT2,XRCC4" Drug 2960_UP Phensuximide [86-34-0]; Up 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "C1QTNF1,SLC4A4,ATP2A2,KIF1A,ADAM23,GYG2,THSD7A,CAPN3,CHRNA4,CLTB,HOMER3,SH2B1,FAM169A,MRNIP,RASGRP2,ST3GAL6,FHL1,HPCAL4,AGAP2,MAN1B1,AFDN,GIT1,POLG,CEP41,RELN,CNNM2,TMEM231,SH3BP2,FNDC3A,ANKRD6,SLC11A1,BTBD7,RBM34,PEG10,DBNDD2,SPTAN1,LHPP,TBCEL,GDPD5,NLRP3" Drug 2961_DN (S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,MARK4,SLC4A4,ADAM23,CD38,AP4M1,EPS15L1,RAB28,IQCK,MAGED1,CSF1,PDE4DIP,DZIP3,RUSC2,TUBD1,FHL1,NOP56,CELF1,ERAP1,SRCAP,AHDC1,GPD2,SLC2A6,ICA1,MAP4,MX1,ZNF862,OGG1,PFKFB4,TMEM231,ZDHHC14,DDN,PJA1,EXOC7,TBL1X,TCF4,ZEB1,CABIN1,FLRT2,NLRP3" Drug 2447_DN Ceforanide [60925-61-3]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADRA1D,APBB2,ARNTL,HIP1R,ARHGAP33,EPS15L1,CREM,DOCK4,DGKG,DTNA,FEM1B,RASGRP2,GATM,ALDH1L1,AHDC1,MSL3,SPACA9,NCKAP1L,MITF,MYO7A,NF1,NINJ2,NPR2,OGG1,PPP3CC,CNNM2,RNASEL,MRAS,SIRT2,SMARCD3,MYH15,SNCA,TMCC1,IZUMO4,SPTAN1,ARHGEF9,TPM2,PLPPR2,SPHK2,PHTF2" Drug 4282_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,AP2A2,PKP4,PPP4R4,SLC4A4,NRP2,CACNA2D2,PLEKHB1,AKAP7,SH2B1,CRY2,EDIL3,MBNL2,EIF5,PTK2B,PRELID3A,OGA,INPP5K,SRCAP,POLL,RASSF8,SHISAL1,IL6ST,NF1,NFIX,CNOT4,RETREG1,STRN3,PID1,RAD51D,NEK11,BTBD7,SNCA,TROVE2,ZC3H4,TMPO,R3HDM1,LAT2,EVI5,SENP7" Drug 3282_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "SRPX,SYNJ2,CCNT1,MAGI1,SOCS6,COL4A5,SH2B1,CTH,KIAA0586,NR1D2,RCAN1,DTNA,F8,ANKFY1,TXNL4A,POLL,GSN,INPP5B,KIF2A,LIG4,MBNL1,CNOT4,NPTX1,NRCAM,PRKACB,PRKAR1B,WDR25,ELOVL2,ZSCAN32,TMEM231,GSTCD,RCOR3,THSD1,NXT2,MTCL1,TRIM2,TMPO,CABIN1,ZKSCAN5,UBE2H" Drug 7024_UP Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,BEGAIN,SLC4A4,ATP2A2,SYNJ2,GYG2,SGCE,MYRF,BAIAP3,HAP1,ARHGAP33,CACNA2D2,ASIC3,SLIT2,NECTIN3,INTS1,MED12,ZNF589,FAM49B,CNTRL,ELOVL5,KCNF1,MAP2,KITLG,NF1,ENPP2,CNNM2,SBF1,FUZ,SLC22A4,CXXC4,COA1,SNCA,KIF13A,CLASP2,ANKRD12,NDRG4,SEMA3B,ST7,KAT6A" Drug 2074_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,ADCY6,PPFIA3,CDK10,CFLAR,HIP1R,WHRN,SMARCAL1,CSNK1E,PARD6A,ABCC5,E2F5,ZNF589,TRMO,SYT17,INPP5K,SESN1,ZNF276,GUCY1B1,INPP5B,MAP4,NPR2,SLC11A2,SETD4,OCRL,RGS4,MAP6D1,SH3BP2,EPN2,ELMO2,BTBD7,ZKSCAN3,ARHGEF9,COBL,EXOC7,FBXW11,TNS2,TRIO,NPDC1,PHTF2" Drug 1756_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADORA1,AGT,APOC1,BCL7A,CD38,ENTPD6,CNTFR,CPS1,ERBB2,ERCC2,AFF2,CRCP,RAB30,TDRKH,DIDO1,CACFD1,PADI2,ACOT7,MAP4,GIT1,NELL2,PALM,PLCB2,PPP5C,PRPSAP2,CCDC40,RGS12,ZNF671,TCP11L1,PKNOX2,CCDC88A,SP4,THSD1,TCF4,NSD1,HSPBP1,NPDC1,ATP6V0E2,ZNF142,LAMP5" Drug 2848_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NME5,APAF1,APOC1,BMP7,CA12,RCBTB2,SLIT2,VAX2,CSF1,DCTN1,PLXNC1,EZH1,BAIAP2,DISC1,GCNT2,AHDC1,MSL3,ATXN2L,KCNH2,KHK,MITF,ZNF862,NNAT,PALM,RETREG1,PLCB2,PURG,MAPK10,ZFHX4,RNH1,EPN2,SLC9A5,KDM4B,SPTAN1,MTCL1,TK2,TRIO,PLPPR2,VLDLR,DNALI1" Drug 4079_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "LTBP4,N4BP2L1,ADAM23,NRP2,HAP1,RGN,CHN2,STOML1,PCYT1B,CSF1R,RIMS2,DTNA,DTNB,EDNRB,REEP2,DCTN2,GPR75,GNG4,CACFD1,HNMT,KHK,LAMA2,MAN2A2,NF1,PCDH9,PDE4D,PLXNB1,PPP1R1A,DCHS2,RGS12,KCTD17,PKNOX2,SNCA,ZC3H13,ARHGAP26,TMPO,KCNK12,ZNF74,NDRG4,PHTF2" Drug 1288_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG3,APBB2,CASK,SLC4A4,CFAP410,CAMK2B,ARHGAP33,RAB33A,CSF1,C2CD2L,CDON,C3orf18,COQ7,PIPOX,PTK2B,FHL1,AGAP2,CGREF1,LILRA2,KCND1,LSS,MAP4,MX1,NRCAM,CCSER2,SLC25A23,CEP41,MASP1,KCTD17,FAM102A,FBXO11,ARFGAP1,DOK5,ZC4H2,ADGRL3,SIN3B,CRTC1,ZNF34,RPRM,ZNF45" Drug 4145_UP Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APBA2,GAS7,PPP4R4,ADAM23,KSR1,MTMR3,CAMK2B,EPS15L1,CNR1,AKAP7,CSF1,ARHGEF10,VCAN,CNTNAP2,DAPK1,PARD6A,HS3ST2,HSD17B14,OGA,GCNT2,GRIK5,IRAK3,KHK,LAMA2,ADAM22,NELL2,NTRK3,PURG,ELOVL2,CCDC40,RGS4,RGS12,DOK5,SP4,NMNAT2,PHLDB1,SYN2,DOCK9,FLRT2,NT5M" Drug 5684_UP Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "C1QTNF3,LTBP4,ATP2B2,CACNB4,CALB1,WHRN,CPS1,CRY2,PDE4DIP,SNPH,ARHGAP24,DGKB,GIT2,HS3ST2,TENM1,TNK2,MRNIP,FHL1,GAD1,TMEM8B,SRCAP,GPR162,LYVE1,BTN2A1,KIF5A,L1CAM,NF1,NFIX,P2RY1,STRN3,TCP11L1,RASA3,PKNOX2,SLC11A1,ARHGAP26,SYN1,ZEB1,HIF3A,EMSY,AP3B2" Drug 4384_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADGRF5,APC,APOC1,PPP4R4,RHBDL1,QKI,SULT4A1,CNTN1,AKAP5,CREM,RIMS2,DGKG,SPOCK2,ETV1,F5,REEP2,ZNF589,CHL1,NEU3,GCNT2,GPER1,AP4S1,ICA1,MIA2,NPY,NOVA2,P2RY1,PFKFB2,PLCD1,MAPK7,GAL3ST4,RNASEL,EMID1,CPEB3,PKNOX2,SLC11A1,SZT2,UCHL1,LAT2,SLC30A3" Drug 6880_DN BAS 012416453; Down 200; 38uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,APBB2,PDE8B,MARCH3,MARK4,BAIAP3,SPAG9,CNOT8,ENTPD4,LYPD1,DMPK,TNK2,DENND4A,ANKMY1,SEMA4D,ALDH1L1,SRCAP,GPR37,GRB10,ADAMTS13,CACFD1,TJAP1,LIG4,SCAMP5,RETREG1,MAPK7,RASGRF1,ZDHHC14,SLC22A4,UNC5B,ZBTB43,PHLDB1,CHST8,ZNF34,TK2,BHLHB9,NR2C2,HIRA,VGF,ZNF24" Drug 3234_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,GAS7,ALDH7A1,BACH1,ST3GAL5,CA12,ARHGEF1,CHRNA4,FAM189A2,PHF14,ZNF804A,SPOCK3,DMPK,AASS,ZNF589,FGFR1,PRELID3A,GFER,KCNJ5,MAN2A2,MAP2,AFDN,MX1,PGAM2,PNMA3,PDZRN4,SNRK,PTPRD,RORB,SH3BP2,SLC2A5,ZHX3,ZNF423,SPTB,ATP10B,ARC,ZEB1,SZT2,SLC19A3,R3HDM1" Drug 7095_DN SC 19220; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "RALGAPA1,BRAP,MTUS1,BIN1,KCNAB2,SOCS6,HOMER3,WHRN,ARHGAP32,GIT2,PARD6A,ERCC2,FHL1,FAM49B,TPK1,SRCAP,FERMT2,GUCY1A1,GUCY1B1,TAGLN3,NPR2,SLC11A2,PDE1C,PLCD1,POLG,PPP5C,C12orf49,SBF1,CCDC88A,TMCC1,ZBTB43,DIP2A,FBXW11,TRIM2,MTMR14,CIAPIN1,VPS35L,SMIM8,ACTR3B,AAAS" Drug 3624_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADORA1,MARK4,BAIAP3,CFAP410,CAMK2B,LRRFIP1,SULT4A1,WHRN,CRY2,ELMO1,SV2B,DPP6,EDIL3,RASGRP2,PTK2B,AFF2,FYB1,FYN,ADAM28,GPER1,ITGA7,LSS,MAP4,MEF2C,NNAT,NPTX1,RETREG1,CEP41,S100B,SLC8A1,SLC11A1,OGDHL,TSNAXIP1,ARC,ZEB1,SZT2,TRIO,FLRT2,VIPR2,SPHK2" Drug 4783_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADD2,FZD9,KCNAB2,FAM131A,ATP6V0A1,CFLAR,SYNJ1,SYNJ2,CFAP410,CD86,CHN2,CHRNA4,RAB33A,WHRN,RASSF2,TENM1,EPHB1,ACSL4,KAT8,FGF13,FGFR1,FHL1,AFF2,GRM8,AP4S1,ICA1,MPP2,TAGLN3,CNOT4,SERPINI1,PLTP,FRMPD1,PKNOX2,STX1A,WSCD1,TRIM2,CABIN1,WIPF1,GDPD5,RNF146" Drug 1825_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "BIN1,APOC1,CDK10,CFLAR,SCARB1,CSF1,CSNK1E,DZIP3,ZFYVE16,TMCC2,FEM1B,SPEG,BAIAP2,CGREF1,GAD1,INPP5K,USP19,FERMT2,SHISAL1,KIFC3,MEIS1,TAGLN3,ZNF862,OGG1,PDPK1,KCTD15,NLE1,RIPOR1,GAL3ST4,FUZ,PEX26,FAM214B,KBTBD4,ARHGEF9,DNMBP,WSCD1,ZEB1,NSD1,CABIN1,SMIM8" Drug 4703_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NME5,LTBP4,ARSE,CDK13,SLC4A4,AZGP1,CA4,SCARB1,SOCS6,CHRNA4,TPP1,FAM149A,CREM,SEC14L5,AFF2,CAMKK2,OGA,GALC,SIGLEC8,RUNDC3A,MSL3,KITLG,AFF1,AFDN,NELL2,NF1,PDE1C,PDE4B,PLCD1,ZSCAN32,KHDRBS2,FRMPD1,SLC11A1,LIMCH1,SPART,PHLDB1,CHST5,ZNF74,PRDM10,ITM2C" Drug 2971_UP Procarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "GAS7,NCOA1,SULT4A1,HOMER3,AKAP7,CLOCK,CSNK1E,VCAN,DOCK4,FAM13A,MRNIP,ENO2,RASGRP2,FER,ADAM28,POLL,STON1,PCLO,BTN2A1,ITPKA,LSS,AFDN,NPR2,PDE4D,CCSER2,PLCL1,PLEC,CNNM2,PTCH1,RGS3,PBRM1,ST6GAL1,ARHGEF40,DBNDD2,SPTB,SYNE1,OBSL1,TNS1,PLPPR2,ZBTB38" Drug 2066_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADCY6,SEMA4G,MARCH3,SLC4A4,ATP2B2,ADGRB2,CACNA2D2,FOXN3,CHN2,CRY2,CSF1,CNTNAP2,DCAF4,EGFR,COQ7,HPCAL4,GCNT2,POLL,GNG4,LPAR4,CACFD1,HSF2,KIFC3,MEF2C,PCDH9,PDE1C,RETREG1,MAPK7,ZNF821,STUM,IFT122,SNCA,UNC5B,SPTB,TCF4,ZNF34,WIPF1,HPS4,PLSCR4,RNF146" Drug 6154_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ADCY6,APOC1,CDC14B,MYRF,CA8,DLGAP2,PDE4DIP,DGKG,SV2B,DMD,SNX29,RASGRP2,ETV1,F5,FGFR1,BAIAP2,AGAP2,FLNC,GCNT2,GFER,LILRB4,PCLO,ICA1,KCNB1,NINJ2,CLDN11,DUSP26,PKIA,NEK11,EMID1,EPN2,LIMS2,PKNOX2,FAIM2,ARHGAP26,RBM26,TRIM2,CRTC1,PARD3,SPHK2" Drug 4348_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "RALGAPA1,ASIC1,ADRA1D,AP2A2,APBA2,APBB2,APC,EPB41L5,PLA2G4C,ARHGEF7,FUBP1,RAB28,PICK1,TBC1D5,HIPK3,FCF1,ING4,OGA,TRAF3IP2,HTATSF1,GNG4,STON1,GRIK5,KHK,MAP4,MIA2,NEK1,RETREG1,LRP12,ELOVL2,CCDC40,ZHX3,TTBK2,TBL1X,WSCD1,ZEB1,TMPO,FLRT2,EMSY,EVI5" Drug 6640_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "KRIT1,CD86,ENTPD4,VCAN,PDE4DIP,USP6NL,CHRDL1,NR1D2,HIPK3,SEMA3D,AASS,ZNF391,FGF1,FGFR1,DCTN2,FYB1,ALDH1L1,GNG4,GSTM5,KCNN1,TM6SF1,AFF1,MMP16,ZNF862,PCDH9,PRPH,WDR25,PTN,TMEM231,SH3BP2,SLC2A5,SPTB,CDK19,PHLDB1,PLCB1,TACR1,SLC44A1,AMACR,LAT2,DPF3" Drug 5110_DN Aztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "MTUS1,ARRB2,STX16,ALDH7A1,FUBP1,SCARB1,SOCS6,QKI,ARMC8,CREM,VCAN,ARHGAP24,DAPK3,EDIL3,FCF1,EGFR,MBNL2,STX2,ANKMY1,GCNT2,PCLO,AGFG1,SCIN,KCNN1,NFIX,PPP3CC,SH3TC2,SUGCT,KIRREL1,CSRNP3,FNDC3A,SNCA,ZNF415,PHLDB1,EXOC7,TMPO,VGF,ZNF711,EVI5,SMIM8" Drug 3618_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "KCNAB2,FAM131A,KIF1A,PICK1,CNTNAP2,DBN1,DMPK,OGA,GAD1,B4GALNT1,SYT17,INPP5K,GLYR1,MSL3,POLL,CNTRL,GSN,INPP5B,MMP16,MMP17,MPP2,SERPINI1,LRP12,PRKAR1B,PTPRO,ZDHHC14,SH3BP2,FBXO11,FAM214B,BTBD7,ZHX3,KDM4C,ZC3H13,KIAA1107,SLC44A1,ZKSCAN5,FAM155A,ZFP37,MPPE1,KAT6A" Drug 3944_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "NDRG2,AP2A2,APBA2,APLP1,CDC14B,SLC2A11,MTMR3,HAP1,AKAP7,CSNK1E,KIAA0586,CDON,SLC12A6,EDN1,EPB41L2,ERBB2,EZH1,FGFR1,FHL1,DLL3,ERAP1,DISC1,GCNT2,SRCAP,MSL3,POLL,KCNN2,NF1,NPY,PFKFB2,ZDHHC14,RGS12,SEMA6D,SUPT20H,SH3BP2,NLGN1,FAM214B,STX1A,PHTF2,ADAMTSL3" Drug 6352_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APLP1,APOC1,CFLAR,MTMR2,TAOK2,SLITRK5,DCAF4,DCAF8,ZNF337,RUSC2,LYPD1,FCGRT,FGFR1,DENND2A,TMEM8B,GPER1,MAP4,ZNF862,MBOAT7,FA2H,APTX,SH3TC2,MAPK12,SBF1,PEX26,KDM4D,CCDC88A,TMCC1,SPTAN1,ZBTB43,STX1A,KANK1,ARHGEF9,PLCB1,TMEM121,TSC2,ZKSCAN5,LMF1,NDRG4,PHTF2" Drug 2368_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,NCOA1,SLC4A4,ATP6V0A1,ADAM23,SYNJ2,SLC25A14,CAPN3,FOXN3,CLCN3,IQCK,HINFP,DTNA,STX2,IGSF6,F8,FGFR1,ATP2C1,GNG4,LILRB4,CNOT4,RETREG1,ZNF426,MAPK3,TMEM104,GSTCD,FUZ,PPP4R3A,ZKSCAN3,SPATA7,UNC5B,CEP68,JMJD6,THRA,KAT6B,FLRT2,LAT2,NT5M,PHTF2,NLRP3" Drug 3475_DN Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ABHD6,AP2A2,AK2,FAM131A,ST3GAL5,CRLF1,TAOK2,FAM189A2,CREM,CRY2,PDE4DIP,INTS1,MFAP3L,MED12,FEM1B,EIF4G2,ING4,ENO2,DISC1,RAB30,GNG4,LPAR4,JAK2,KHK,MAP4,GIT1,LYRM9,PDPK1,RETREG2,POLG,PRPH,ZSCAN32,NEK11,FERMT1,FUZ,ABLIM3,EPN2,SOX3,LHPP,CDK20" Drug 3337_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "ASIC1,NDRG2,C1QTNF1,ALCAM,BIN1,LDLRAD4,CFAP410,RHBDL1,CHN2,NECTIN3,ENTPD4,CNTNAP2,DMPK,EDN3,MBNL2,TNK2,VPS13B,FHL1,AGAP2,GPD2,LPAR4,GPER1,GRIK5,VSIG4,LAMA2,MX1,POU6F1,ZSCAN32,CCDC40,TRIM68,KCNIP1,RASA3,PEX26,SLC11A1,SNCA,TRIM2,OBSL1,CABIN1,TRIO,NT5M" Drug 6443_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "APBA2,PPP4R4,ARHGDIG,SLC4A4,RGS11,LDLRAD4,CACNA2D1,CAMK2G,CLGN,COL9A3,CSF1,PDE4DIP,MTSS1L,ANKMY1,FER,NSG1,FYN,GFER,NTRK3,CDK18,NLE1,SLC25A23,LRRN3,PPP5C,PTH1R,TRIM68,RGS12,CCDC25,TCP11L1,RPS6KA2,ASAP3,COA1,SNAP25,IZUMO4,HECW1,PEG10,PLCB1,SYT5,VSNL1,XRCC4" Drug 7130_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "GAS7,CDK10,KIF1A,KYAT1,CSF1R,OSBPL3,PDE4DIP,CNTNAP2,CYBB,RUSC2,SGSM2,MAMLD1,FCGRT,ZNF589,FER,OGA,GAD1,USP19,RNFT2,INPP5B,PLCD1,MAPK7,KLK6,CNNM2,BCAS3,PTN,PTPRN2,SBF1,SH3BP2,ST6GAL1,WDR37,LIMS2,ZKSCAN3,TSPYL2,PHLDB1,PLCB1,WIPF1,MPPE1,EPM2A,ST7" Drug 4800_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "AP2A2,LTBP4,AMPD2,BIN1,PPFIA3,MARK4,CFLAR,HAP1,KYAT1,ARHGAP33,SLIT2,SH2B1,CSNK1E,SEZ6L2,TSPAN5,PLXNC1,FGFR1,BAIAP2,CACFD1,ELOVL5,MAP4,MITF,PLEC,PLXNB1,FA2H,WDR25,PTPRE,RIPOR1,KCTD17,ANKRD6,KIF13A,TROVE2,CEP68,TTBK2,TACC1,KIAA0930,TK2,CDK20,REEP1,MAP3K12" Drug 6485_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "CA4,CALB2,CNN3,FAM149A,VCAN,RIMS2,GPRASP1,BRINP1,SLC12A6,ECM2,MBNL2,EGR3,RASGRP2,EPHB1,CDKL3,FGFR1,OGA,GATM,SESN1,ZNF276,GLI2,GLYR1,POLL,ENPP2,SMIM7,CCDC40,KCTD17,SEMA6D,SBF1,ST6GAL1,CNKSR2,MYH15,FAIM2,NXT2,ARC,EXOC7,WSCD1,TRIM2,SLC44A1,LAT2" Drug 5598_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 40 198 "SEMA6A,AMPD3,AMPH,APC,BACH1,GYG2,CA4,CBFA2T2,AKAP5,CSF1R,SNPH,RASSF2,DAPK1,DMPK,ZNF44,ERAP1,SIGLEC8,GLYR1,STON1,GPR37,AP4S1,AFDN,MMP16,ADAM22,PCDH9,PDE1C,SERPINI1,LRP12,MAPK7,FAT4,KCTD17,FAM214B,KDM4B,TSNAXIP1,IZUMO4,RGL1,TRO,TRPM2,FAM155A,SLC17A7" Drug 3536_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 38 185 "ADGRF5,AMPD3,ARNTL,DNAH17,CFLAR,ARHGEF2,CLGN,FOXN3,STOML1,SOCS5,EXOG,DTNA,MBNL2,FGFR1,SEPT9,INPP5K,GNG4,GRB10,ATXN2L,ICA1,IL6ST,KPNA5,MPP2,ADAM22,MX1,RIPOR1,RPS6KA2,PPM1E,SYBU,KANSL3,SMARCD3,ZNF415,TRIM2,PCDHA6,TK2,TRIO,UGT8,VLDLR" Drug 2142_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-04 1.00E+00 2.43E-03 2.74E-02 38 185 "ABHD6,ADGRF5,BIN1,DDO,APOC1,PROM1,CACNB4,USP2,SLC16A4,SEPT7,PICK1,SIPA1L1,RIPOR2,PHC2,TNK2,CAMKK2,TRAF3IP2,ADAM28,ZNF276,GLUL,GSN,ICA1,LYRM9,ZNF862,NRCAM,PLCL1,ACSM5,MARCH1,RFX2,GALNT10,FNDC3A,SLA,SOX15,SAMSN1,KANK1,ASTN2,SPHK2,KCNAB1" Drug 2794_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.16E-04 1.00E+00 2.56E-03 2.89E-02 37 179 "ABHD6,ALCAM,ST3GAL5,BAIAP3,CBFA2T2,CLGN,PDE4DIP,ARMCX2,TSPAN5,OPTN,HPCAL4,FYN,CYP46A1,STON1,MAP2,MXI1,NEK1,PCDH9,SERPINI1,PKIA,GRAMD1C,PRPH,SH3GL3,PPM1E,WDR47,PKNOX2,LIMCH1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,ZNF45,REEP1,SLC17A7,ITM2C" Drug 4762_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.16E-04 1.00E+00 2.56E-03 2.89E-02 37 179 "RALGAPA1,SEMA6A,ALCAM,APBA2,LGR5,NRP2,CA4,ARHGEF2,CLGN,COL9A3,RCHY1,MBNL2,VPS13B,AMOTL2,OGA,FYN,ERAP1,TMEM8B,NEU3,GRB10,ADAMTS13,ICA1,LAMA2,MIA2,PGAM2,PRKCB,C1orf54,EMID1,PPM1E,LIMCH1,TSNAXIP1,KDM3A,TRIM2,BCL2L13,VLDLR,LAT2,SENP7" Drug 2722_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "ADRA1D,APC,ARRB1,NUMB,STX16,N4BP2L1,CACNA1A,CAST,RAB28,CSNK1G3,VCAN,PPP1R16B,DTNA,CELSR3,MRNIP,EPB41L2,OGA,FYB1,SEPT9,ARFIP1,LILRA2,PADI2,ITGAM,LIG4,LSS,AFF1,ZNF862,ENPP2,MINDY2,MAPK7,SNRK,RNASEL,FUZ,PEX26,SS18,NXT2,ZEB1,TMPO,WIPF1" Drug 2450_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "NDRG3,MTUS1,BEGAIN,APBB2,STX16,MPDZ,GYG2,HIP1R,RAB26,CNTN1,CRMP1,CSF1,PDE4DIP,FAM131B,DOCK4,DBT,MAMLD1,ETV1,TLR7,PTK2B,BAIAP2,TRAF3IP2,SIGLEC8,STON1,IFI16,KCND1,KCNH2,MAP4,MEF2C,AFF1,PCDH9,DUSP26,PLCL1,RPS20,DNMBP,RPGRIP1L,AP4E1,LMF1,FZD3" Drug 7155_DN Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "NME5,APBB2,SLC4A4,CFLAR,SCAPER,CAMK2G,SLC25A14,ARHGAP32,FEM1B,IRAK4,VPS13B,COQ7,ZNF589,ANKFY1,DLL3,INPP5K,SRCAP,COPS8,POLL,GPD2,ITPKB,LIG4,NF1,NFYA,SLC11A2,PLCD1,KLK6,SNRK,SUGCT,ATXN2,AMBRA1,LIMCH1,ARHGAP26,ARHGEF9,KIAA0930,TNS2,ZNF34,SMIM8,RNF146" Drug 6188_DN clozapine; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "ASIC1,MTUS1,FAM131A,SEMA4G,ZSCAN18,BMP7,SCAPER,SLC25A14,PLAA,BAG4,CRY2,OSBPL3,PPP1R16B,GSDME,COQ7,CDKL3,SRCAP,MAN1B1,ATXN2L,MYO7A,P2RY1,PILRA,SEC14L1,MRAS,SLC11A1,TSPYL2,SZT2,AP4E1,PARD3,TPM1,ZKSCAN5,FLRT2,PLPPR2,VIPR2,ATP6V0E2,REEP1,MAP3K12,GDPD5,PCBP4" Drug 2699_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "MTUS1,AMT,ANK2,SLC4A4,KIF1A,CAMK2G,HIP1R,CBS,CLGN,PLAA,HOMER3,NCOR2,CTH,NR1D2,DTNA,MBNL2,RASGRP2,ZNF589,ZNF276,GRB10,PADI2,ATXN2L,LSS,MAP4,PTPRO,RIPOR1,FAM184A,IZUMO4,DDN,EXOC7,TCF4,TNS1,CDK20,SMUG1,FLRT2,VIPR2,MAP3K12,EMSY,HPS4" Drug 3114_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "CDC42BPA,MYOM1,PROM1,BMP7,SGCE,CHN2,LHX2,RAB26,CREM,SLITRK5,DTNB,CELSR3,ETV1,FGFR1,GATM,ADAM28,RUNDC3A,FAM69A,MAP4,SCAMP5,NOVA1,NRCAM,PCDH9,PLCL1,PMP22,CEP41,PTPRB,PTPRN2,TMEM255A,GAL3ST4,SATB1,SPTB,TBCEL,TRIM2,TRPS1,FLRT2,TRIM9,SLC17A7,KCNAB1" Drug 1284_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "ABHD6,BIN1,APBB2,APC,SLC4A4,ST3GAL5,SCAPER,SGCE,HIP1R,KYAT1,CBFA2T2,CLGN,PDE4DIP,SLITRK5,DZIP3,DOCK4,TSPAN5,PLXNC1,EPB41L2,EXTL2,FGFR1,IFI16,ITGA7,MAP4,MEF2C,SLC25A23,PMP22,SATB1,ANKRD6,ELMO2,ZNF667,KDM4B,CEP68,RGL1,STXBP1,DNMBP,TCF4,TRIM9,EMSY" Drug 3252_DN Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.17E-04 1.00E+00 2.57E-03 2.89E-02 39 192 "MTUS1,AK2,C1QTNF3,APLP1,PPFIA3,STX16,CFLAR,BMP7,SYNJ2,CSF1,SIPA1L1,GREB1,SUGP2,CGREF1,OGA,ZNF44,DISC1,TJAP1,IL6ST,MAP4,MITF,ADAM22,PIK3R1,PRKAR1B,RGS12,SLC25A36,GSTCD,SBF1,TRA2B,RASA3,FUZ,DOP1A,POGZ,PRRC2C,TACC1,TBL1X,BHLHB9,KAT6B,REEP1" Drug ctd:D003375 Coumestrol CTD 2.21E-04 1.00E+00 2.61E-03 2.94E-02 251 1796 "RALGAPA1,ABCF1,C3orf14,FMNL2,KIAA1211,ESYT2,MTUS1,KIAA1324,TAOK1,ALCAM,PCDH10,APBB2,EPB41L5,CDC14B,ARHGDIA,CDK13,ZBTB10,NCOA1,RASL11B,EIF4G3,N4BP2L1,BARD1,BCS1L,BLM,CFLAR,BMP7,AP1M1,C5,RAB29,CA12,VXN,CAST,CBR1,SCARB1,SYNGR3,ENTPD2,DCLK1,MAGI1,CCPG1,CHN1,LHX2,EPS15L1,FAM189A2,MAP4K4,IQCK,FAM171B,CDC42BPB,ENTPD4,ABCG1,LRIG1,CSNK1G3,SOCS5,FAM169A,PNPLA8,GREB1,DCAF4,CENPL,KIAA0586,DBN1,FBXL5,RHOBTB1,SACS,FAM107B,USP3,CPEB2,CASP8AP2,PDCD6IP,DTNA,FARSB,ABCC5,DNM1L,E2F5,EDIL3,SNX29,EDN1,FCF1,RASGRP1,KLHL5,OPTN,PHF20L1,KMT5B,EGR3,TUBD1,EPB41L2,COQ7,ERBB2,ERBB4,MRPL37,KATNAL1,CD320,SH3YL1,TAOK3,CEP78,STRADA,FDFT1,PRMT5,OLFM1,POLR1B,FGFR1,TMEM164,MAD2L2,AMOTL2,FHL1,SEC23B,IP6K2,SYNCRIP,FOXO3,NBEA,TMEM107,SMC2,FAM49B,ATP2C1,CSPG5,OGA,ZNF44,SYT17,SEPT9,TUBGCP4,RUNDC3A,DBF4,RAB40B,FERMT2,GPD2,GPER1,GRB10,ZNF496,CIT,PSIP1,UBE2QL1,FRMD3,ELOVL5,ACOT7,ICA1,IL6ST,ZNF678,KTN1,L1CAM,STMN1,LIG4,SYTL4,NCOA7,MATN3,TM6SF1,MMP16,MXI1,MYO5A,MYO6,SFR1,NELL2,NRCAM,OXTR,PCDHGC3,PIK3C2A,SNX10,PKM,GPSM2,FAM216A,PMP22,STRN3,SH3KBP1,PPP2R5E,PPP3CC,PPP5C,PRKACB,MAPK3,SLC26A11,BCAS3,VPS13C,ELOVL2,SPDL1,NKAIN1,TUG1,ACSS3,RBBP8,RET,ERI2,UBR7,FAM161B,CLIP1,RMI1,SAFB,GALNT10,TRA2B,HSPA4L,PPM1E,ARX,SHMT2,R3HDM2,SYBU,NBPF1,SEPHS1,SLC12A2,SLC12A4,ELMO2,BTBD7,COA1,CDK5RAP2,RCOR3,IFT122,TMCC1,FAM126B,TRERF1,SOX3,SPATA7,FNBP1,KDM3A,ZSWIM8,MYCBP2,SPART,SEPT8,SULF2,PRRC2C,SYNE2,DNAJC9,TMEM150C,COBL,TBL1X,SATB2,OBSL1,DICER1,SIRT1,ITGB3BP,CBX5,TMPO,PARD3,TPM1,ELP5,PDSS1,RUNDC3B,TSN,TSC2,SSBP2,TUBB2A,SGK3,RPRM,UBE2H,USP1,CCDC14,RICTOR,ZIC1,LYPD6,ZBTB38,TMEM237,FTSJ1,EVI5,DOCK8,KAT6A,PHTF2,AAAS,FRMD6,NETO2" Drug CID006445562 EKB-569 Stitch 2.21E-04 1.00E+00 2.61E-03 2.94E-02 22 87 "CLK4,BTK,CSNK1E,DAPK3,EGFR,TNK2,EPHB1,ERBB2,ERBB4,FER,CAMKK2,FYN,MAP4K5,MYLK2,JAK2,KIT,LSS,MAPK3,PTK2,RPS6KA2,TEK,EPM2A" Drug 3333_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NME5,SEMA4G,BACH1,KSR1,BAIAP3,CFAP410,CLDN10,CDH2,CHN2,TAOK2,LHX2,TPP1,PICK1,AKAP6,CSF1R,PDE4DIP,CNTNAP2,SNPH,ELMO1,EDN1,MBNL2,PCDH17,GRIK5,GSN,GSTM5,NXPH3,TM6SF1,PCBP3,SAMD9,ZDHHC14,RGS12,CNKSR2,KDM4B,TSNAXIP1,ZC3H13,CLSTN2,HIF3A,TRPM2,WIPF1,ITM2C" Drug 5737_DN Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,NME5,APLP1,PPFIA3,CDK10,STX16,ALDH7A1,CFAP410,ASIC3,B4GALT6,TAOK2,RAB28,SULT4A1,CSF1,ARHGEF10,CNTNAP2,TBC1D5,CDON,ETV1,FGF1,FGFR1,TRMO,CGREF1,OGA,INPP5K,MSL3,INPP5B,NF1,SERPINI1,MAPK3,PTPRN2,RIPOR1,FAM184A,RGS4,FAM155A,UGT8,TFIP11,UPF3A,UBE3B,PHTF2" Drug 4795_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ABHD6,MTUS1,CDC42BPA,EP400,MAP4K3,EPB41L5,APOC1,ARNTL,MTMR2,HAP1,LHX2,VAX2,SH2B1,SOCS5,TBC1D5,DBT,FBXL5,DTNA,MAMLD1,EDNRA,PDLIM5,CAMKK2,CGREF1,DHX35,JAK2,MIA2,NRCAM,STRN3,PTK2,ZDHHC14,KCTD17,ZNF821,LIMCH1,KIF13A,IQSEC2,SPART,ASTN2,KIAA0930,TMEM121,TIGD6" Drug 6300_DN Dextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BIN1,CDC42BPA,ZBTB10,KYAT1,CCNT1,AP4M1,HAPLN1,ARHGEF4,KIAA0753,SPOCK3,OPTN,RGS17,DENND4A,F8,TRMO,CINP,FYN,DISC1,CRCP,JAK2,L1CAM,MAP4,MEIS1,MN1,NOVA1,SLC11A2,SLC25A23,PRPH,PTPN13,SH3TC2,GAL3ST4,SBF1,UNC5B,ZBTB43,SS18,IQCE,TRIM2,CLDND1,XRCC4,UPF3A" Drug 5872_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDK10,PPP4R4,CFLAR,CACNA1I,CFAP410,CACNA2D1,ARHGEF1,RAB26,ARHGEF4,PYGO1,CELSR3,MBNL2,PLXNC1,NCALD,FGFR3,SCARA3,DISC1,LPAR4,SPACA9,NXPH3,SCIN,KCNF1,KIF5A,MIA2,AFDN,NNAT,DUSP26,POLG,SAMD9,PTPRN2,KCTD17,FBXW7,ARHGAP26,MCF2L,TAL1,UBTF,WIPF1,LAT2,ZNF74,DPF3" Drug 6444_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AK2,AMPD3,APOC1,CDK10,PLA2G4C,DNAH17,MARK4,CFLAR,LDLRAD4,BAG4,ENTPD4,TM9SF4,LYPD1,EGR3,IRAK4,FGFR1,FAM49B,PRELID3A,INPP5K,ZNF276,HNMT,ITPKB,IPO5,MAPT,PDCD2,RIPOR1,CEP97,RGS3,DCUN1D2,ROBO1,NEK11,SAFB,SYBU,FBXW11,SLC44A1,ZKSCAN5,UBTF,REEP1,HPS4,ACTR3B" Drug 348_DN 2-propylpentanoic acid; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "KDM5D,NDRG2,BRAP,KCNAB2,GAS7,SEMA4G,MARCH3,BMPR1B,CHGB,CHRNA4,HOMER3,SH2B1,AATK,ING4,STX2,ZMYND10,DCTN2,FOLR2,KHDRBS3,ADAM28,TXNL4A,RNFT2,ATXN2L,NNAT,NPTX1,POLG,MAPK7,SUSD4,GAL3ST4,RGS3,KLHL11,TCP11L1,ZHX3,PHLDB1,CRTC1,WIPF1,ZNF154,GDPD5,MPPE1,HRASLS" Drug 2320_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "C1QTNF3,CDC14B,MARCH3,MARK4,ST3GAL5,ARHGEF1,SCARB1,TAOK2,SIPA1L1,DZIP3,LYPD1,ZNF589,FHL1,TXNL4A,MSL3,PRRC2B,TDRKH,GRIK5,GSN,ATXN2L,KCNN1,ZNF862,CDK18,SLC25A23,PPP2R2B,ELOVL2,SBF1,FNDC3A,FAM214B,SPTAN1,EXOC7,KIAA1107,TRIM2,TNS2,CRTC1,PARD3,PLPPR2,GDPD5,SEMA3B,KAT6A" Drug 1623_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG3,NDRG2,ADD2,APBB2,SHROOM2,CBFA2T2,IQCK,NCOR1,PPP6R2,CYBB,SPOCK2,FGFR1,NSG1,ALDH1L1,TDRKH,LILRA2,PADI2,NXPH3,TJAP1,KCNB1,MPP2,GIT1,KCTD15,PLEC,POLG,MAPK10,PRPH,ATXN2,SH3BP2,EPN2,FAM214B,CCDC88A,SPTB,NXT2,EXOC7,MGRN1,ZMAT3,WBP2,VGF,ST7" Drug 4838_DN Tocainide hydrochloride; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,ADRA1D,AMT,APBB2,FAM131A,APOC1,CDC14B,MARK4,SYNJ2,GYG2,PDE4DIP,MFAP3L,TSPAN5,MTSS1L,NCALD,DLC1,FGFR1,SCARA3,FAM49B,ERAP1,DISC1,GNG4,TDRKH,GRIK5,MAP4K5,HSF2,KCNH2,NF1,NFYA,PDE4B,PPARA,PPP2R2B,SAMD9,FNDC3A,UNC5B,SLC44A1,THRA,VIPR2,WIPF1,TIGD6" Drug 3337_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADRA1D,AP2A2,APBB2,HAP1,ASIC3,VAX2,CNTN1,WHRN,NCOR1,CSF1,HSD17B14,KAT8,SEMA4D,PRELID3A,DISC1,SEPT9,GCNT2,RAB30,ICA1,KCNJ5,MITF,CNOT4,SLC11A2,PLCD1,PRODH,TMEM104,KCTD17,ZNF821,SGK1,SH3BP2,SYBU,PPP4R3A,SLC6A8,IQSEC2,ELOVL4,PLCB1,MCF2L,KIAA1107,SLC44A1,VIPR2" Drug 7234_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AK2,TRMT9B,AMH,APOC1,PLA2G4C,SLIT2,FAM189A2,MYRIP,HAPLN1,SPOCK3,CNNM1,RASGRP2,BAIAP2,PDLIM5,OGA,SRCAP,POLL,ELOVL5,ITPKB,LSS,MGAT3,PRKCB,MAPK10,RASGRF1,SH3GL3,SYBU,PREX2,SLC2A5,FAIM2,KDM4C,IQSEC2,ANKRD12,MCF2L,TRIM2,CRTC1,ZNF34,RUNDC3B,TUBB1,VSNL1,SEMA3B" Drug 3750_UP Deltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "PKP4,GAS7,PPP4R4,ARHGDIG,CDK13,PDE8B,AZGP1,HIP1R,LARGE1,SULT4A1,COL9A3,SUSD5,MFAP3L,SV2B,MRNIP,RASGRP2,FAM198B,SEMA4D,PDLIM5,GALC,CYP46A1,ADAM28,PRUNE2,KCNB1,MAN2A2,PNMA3,GDPD2,EMID1,SEMA6D,SLC6A11,BTBD7,MYH15,DOK5,KDM4C,CUX2,HIF3A,NR2E1,CDK20,TUBB1,NLRP3" Drug 2454_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BEGAIN,APAF1,FAM131A,CDC14B,ARHGDIG,N4BP2L1,RIPK1,KIF1A,CFLAR,RUNX1T1,SLIT2,AKAP6,SIPA1L1,GPRASP1,ARHGAP32,DAPK3,FCF1,EIF1,FGF12,BAIAP2,DENND2A,SIGLEC8,SRCAP,TPPP,KCNJ5,MYCN,NFYA,PLCD1,EPB41L4B,WDR25,KHDRBS2,PLPPR3,KDM4B,TROVE2,NXT2,SYT5,CUX2,PIK3R5,TRIO,ADAMTS9" Drug 2023_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "C1QTNF1,APC,BCL7A,CAST,SEPT7,SRSF11,EPS15L1,SPOCK2,RCAN1,APH1A,ING4,ETV1,KAT8,FYB1,NEU3,CACFD1,TJAP1,SCAMP5,NELL2,SLC11A2,PLCB2,RETREG2,MAPK10,SPDL1,C1orf109,TTC13,PID1,RDX,PCMTD2,TCP11L1,CCDC88A,ELMO2,INTS9,ZC4H2,PHLDB1,PLCB1,TCF4,NPL,HIRA,XRCC4" Drug 2287_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AMPD3,CDC42BPA,APBA2,GAS7,CAMK2B,RUNX1T1,CACNA2D2,QKI,SIPA1L1,DZIP3,RASSF2,TBC1D5,PLXNC1,ACSL4,FHL1,TPK1,ALDH1L1,SRCAP,PRRC2B,HNMT,ADAM22,NF1,CDK18,LRP12,MAPK10,PTN,FBXW7,SH3BP2,PEX26,LIMCH1,KDM4B,SPART,SYN2,TNS1,VIPR2,ZFP37,SPHK2,SLC30A3,TIGD6,SENP7" Drug 4484_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NME5,C1QTNF1,CDC42BPA,SEMA4G,SCAPER,CAMK2G,SOCS6,ARMC8,WHRN,SNPH,EDIL3,CNNM1,STX2,ZNF589,FAM49B,SYT17,DISC1,GNG4,SCIN,KIF2A,MAPT,MEF2C,MEIS1,MIA2,PTN,GSTCD,NEK11,ASAP3,PEX26,SLC14A1,BTBD7,KDM4C,UNC5B,IQSEC2,JMJD6,SYT1,ZEB1,CRTC1,CABIN1,RPRM" Drug 7477_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "DOC2A,CDK13,CALB2,CBFA2T2,CREM,GIT2,MFAP3L,DNM1,CELSR3,MRNIP,ERCC2,DENND4A,FECH,FGF12,BAIAP2,SEMA4D,B4GALNT1,ALDH1L1,RAB30,GRB10,RNFT2,ICA1,IL6R,KCNH2,KCNN1,LMO2,MAPT,ZNF862,RETREG1,PLXNB1,RIPOR1,CEP97,GSTCD,SLC11A1,VPS13A,COBL,KIAA0930,DICER1,ZNF34,VLDLR" Drug 5853_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,NME5,DDO,CDC14B,PPP4R4,ADAM23,SYNJ2,RAB29,MYRF,SULT4A1,AKAP7,SLC4A8,RNF14,DTNA,TENM1,DLC1,AGAP2,DLL3,GPR37,IGF1,KIT,PLCD1,POLG,PPP5C,MAPK10,SAMD9,BCAS3,PTN,FAM184A,RGS12,ZNF334,SAMSN1,PLCB1,ARC,TRIM2,SLC44A1,TIAM1,WIPF1,ZNF711,GAN" Drug 2985_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,ABHD6,DOC2A,AMPH,APC,PDE8B,NRP2,KALRN,CAMK2A,LARGE1,CHN2,TAOK2,STOML1,CNN3,NCOR2,SIPA1L1,PDE4DIP,MYEF2,MFAP3L,SPOCK3,EGR3,PRELID3A,NSG1,GAD1,ADAM28,GLI2,KCNQ3,SMAD1,AFDN,MSR1,NNAT,NRCAM,PDE4D,FSD1,PTPRN2,NEK11,TSNAXIP1,ADGRL3,ZKSCAN5,FLRT2" Drug 4068_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BEGAIN,CDC14B,PPP4R4,ARRB1,CFAP410,CA12,CACNA2D1,KALRN,CAMK2B,RUNX1T1,ENTPD2,SULT4A1,PCYT1B,HAPLN1,PPP1R16B,HEPH,C2CD2L,FRY,ING4,HPCAL4,AGAP2,SIGLEC8,ADAM28,CACFD1,MYO7A,NPY,NPTX1,NTRK2,ENPP2,PRKCB,SEMA6D,ASAP3,KANSL3,DOK5,ARHGAP26,NFASC,PLCB1,HIF3A,TPM2,RPRM" Drug 7362_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDC42BPA,ARHGDIG,PDE8B,BMP7,LDLRAD4,CACNA2D2,FOXN3,PICK1,WHRN,AATK,CNTNAP2,CYBB,CHRDL1,COQ7,ZNF549,FGFR1,AGAP2,FYB1,ZNF44,GLYR1,GNAL,HLF,ICA1,LMO2,PACRG,MMP16,PPP2R2B,CNNM2,ZCWPW1,EMID1,SNCA,ARHGAP26,DDN,KLHL4,SLC44A1,CABIN1,TRIO,VIPR2,XRCC4,REEP1" Drug 4392_UP Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,SEMA6A,MARK4,PTCH2,ATP1A3,NRP2,GYG2,SGCE,AATK,CSF1,PARD6A,TMCC2,AGAP2,PDLIM5,GAD1,CPLX2,GNAO1,GPER1,ADAMTS13,ITGA7,KCNF1,KIF5A,MAPT,MEF2C,ADAM22,NPY,OPRL1,CEP41,RGS4,RPS20,SATB1,ASAP3,SNCA,FAIM2,PEG10,ATP10B,KIAA1107,DOCK9,KCNAB1,GJC2" Drug 5443_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,NDRG3,C1QTNF3,PDE8B,MARK4,KIF1A,SYNJ2,QKI,NECTIN3,SIPA1L1,SOCS5,CNTNAP2,EIF4G2,SCML2,BAIAP2,ANKFY1,GALC,DISC1,GLYR1,RAB30,GPER1,GRIK5,ELOVL5,HNMT,IL6ST,NFYA,LRP12,MBOAT7,ELOVL2,BTBD7,MAPKBP1,KDM4C,PLCB1,MCF2L,EXOC7,IQCE,TRIM2,CABIN1,SMIM8,GAN" Drug 4523_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,ADCY6,AP2A2,QKI,WHRN,ABCG1,PDE4DIP,CNTNAP2,TBC1D5,RUSC2,PLXNC1,TENM1,MRNIP,ETV1,DLL3,TRAF3IP2,SYT17,USP19,STON1,MX1,NEK1,NF1,CNOT4,STRN3,MAPK3,MAPK7,PID1,FBXW7,SUPT20H,EPN2,SIRT2,ELMO2,IQSEC2,ZBTB43,CRTC1,TMEM121,TIAM1,LAT2,WNT7A,XRCC4" Drug 3066_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,ABHD6,ADORA1,APC,SCAPER,THSD7A,SLIT2,CNTN1,CRY2,CNTNAP2,HS3ST2,EDNRA,ZNF549,ETV1,FGFR1,KCNMB4,PADI2,MAP4,GIT1,NTRK2,PDE4D,PFKFB4,SLC25A23,CEP41,CNNM2,ZNF493,GAL3ST4,RGS12,ZFHX4,ANKRD6,SNAP25,PDZD2,PEG10,SEPT8,TBCEL,PCDHGA10,CRTC1,DICER1,NDRG4,FZD3" Drug 6126_DN Natamycin [7681-93-8]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,MTUS1,AMPD2,PKP4,CDK13,N4BP2L1,SCAPER,CAPN3,TMEM184B,ARHGEF10,SLITRK5,PPP1R16B,DCAF8,RCAN1,DTNA,FAM13A,NCALD,ERAP1,ATXN2L,NFYA,PDE4A,PDE4B,PDE4D,RIPOR1,PID1,GSTCD,CLIP1,RASA3,FAM214B,KBTBD4,SNCA,ITPRID2,ARHGEF9,ZNF34,R3HDM1,ZKSCAN5,LAT2,ZBTB38,PHTF2,NLRP3" Drug 6315_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,NME5,PKP4,PPFIA3,SHROOM2,HAP1,NRXN3,HOMER3,GAL3ST1,CPS1,SLITRK5,APPL1,PHF14,ARMCX2,COQ7,RRAGB,FGFR1,FLT1,FYN,DENND2A,GALC,TMEM8B,INPP5K,ZNF276,AP4S1,HNMT,JAK2,MX1,GRAMD1C,CNNM2,GSTCD,TCP11L1,SUPT20H,ZFP30,KIAA1107,SZT2,ZBTB14,NT5M,KCNAB1,PHTF2" Drug 3353_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NME5,APC,SLC4A4,ATP2A2,BAIAP3,KALRN,RUNX1T1,FAM189A2,NCOR2,RUSC2,FRY,CELSR3,LRRC17,ERCC2,DLC1,OLFM1,FHL1,FLNC,PDLIM5,GAD1,INPP5K,RUNDC3A,GLYR1,GRM8,C2orf72,ITGAM,KCNQ3,LAMA2,NF1,PCDH9,PDE4B,CEP41,C1orf54,ZNF493,SLC9A5,ZC3H13,TBCEL,ZFPM2,VIPR2,EMSY" Drug 7028_UP Isoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "SEMA6A,APBB2,ARRB1,CFLAR,MTMR3,GYG2,CA4,CBFA2T2,PDE4DIP,ARHGEF4,RUSC2,DMPK,RCAN1,EDNRA,MBNL2,ENO2,F5,FHL1,AGAP2,IQCG,FAM49B,GAD1,GLYR1,GRB10,SLC2A6,ATXN2L,ELOVL5,LSS,KITLG,PTCH1,FBXO11,SNCA,PLCB1,KIAA0930,ZNF34,SLC44A1,KCNK12,SPHK2,MAP3K12,ST7" Drug 7465_UP Spaglumic acid [4910-46-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "SEMA6A,BIN1,AMT,APC,DNAH17,BMP7,KYAT1,MAGI1,SPOCK2,DNM1,DTNA,CELSR3,PRELID3A,SYT17,RUNDC3A,RNFT2,AFF1,MPP2,NELL2,NF1,PCDHGC3,PRKAR1B,ZSCAN2,ZFHX4,TCP11L1,FRMPD1,PREX2,PPP4R3A,SLC11A1,CXXC4,TSNAXIP1,ZBTB43,CEP68,TBL1X,TRIM2,TIAM1,REEP1,SEMA3B,EPM2A,MARCH8" Drug 3224_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,AK2,FAM135A,GAS7,BACH1,CFLAR,MTMR3,RUNX1T1,CNTNAP2,RIMS2,SNPH,EDN3,PLXNC1,PIPOX,ZNF589,FGFR3,ZNF44,ERAP1,RUNDC3A,RAB30,LPAR4,GRIK5,C2orf72,KCNH2,MAP2,TAGLN3,TREM2,MBOAT7,PKNOX2,SNCA,FAIM2,DOK5,ARHGAP26,SPTB,ATP10B,SYT5,DOCK9,HIF3A,TPM2,XRCC4" Drug 4295_UP Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "SEMA7A,PKP4,BMP7,MTMR3,RCHY1,JAKMIP2,DTNB,EDNRA,NCALD,REEP2,AGAP2,FYB1,ERAP1,ALDH1L1,IL6R,LMO2,MYT1,NPTX1,NPTX2,NTRK3,OPRL1,PFKFB4,PPARA,CEP41,PRKAR1B,PRPH,PTPRN2,CCDC40,EMID1,CPEB3,DZIP1,RBM34,SPP1,ZC3H13,ARC,ADGRL3,SMG6,TIAM1,TIMP4,EPM2A" Drug 7250_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDC42BPA,SHROOM2,ARRB2,ADAM23,CFLAR,LDLRAD4,CACNA2D2,RAB28,CRY2,PPP6R2,FAM131B,ARHGAP24,DTNA,EGFR,IRAK4,FGF13,BAIAP2,TRMO,CSPG5,MSL3,BTN2A1,NFYA,SLC25A23,STRN3,PPP5C,WDR25,ZDHHC14,GTDC1,ATXN7,PEX26,SPTB,IQSEC2,SEPT8,CEP68,ASTN2,MTMR14,CHST5,WIPF1,NDRG4,NT5M" Drug 6053_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,NDRG2,ADORA1,LTBP4,BIN1,APBA2,GAS7,SEPT7,CRLF1,FOXN3,TAOK2,ABI3BP,CRMP1,CSF1,RASSF2,DAPK3,TOM1,FYB1,SRCAP,MSL3,POLL,RASSF8,MATK,ZNF862,ZDHHC14,SEMA6D,NLGN1,PKNOX2,DOP1A,TSNAXIP1,ZHX3,ZC3H13,ZEB1,SZT2,PARD3,VGF,XRCC4,KCNAB1,PLSCR4,KAT6A" Drug 3898_DN Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BIN1,MARK4,SYNJ2,SCAPER,BAIAP3,CA4,HIP1R,FOXN3,STOML1,SH2B1,CSF1R,RIMS2,STX2,NCALD,ZNF589,SCARA3,GCNT2,SRCAP,RUNDC3A,GRM8,KHK,MATK,MID1,AFF1,NF1,FAT4,FAM214B,PKNOX2,SNCA,SPTB,KIAA1107,WSCD1,TRIM2,DOCK9,THRA,HEY1,TK2,CABIN1,VIPR2,GDPD5" Drug 4259_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AGT,N4BP2L1,CACNA1I,CACNA1G,FAM149A,CABP1,NRG2,HAPLN1,NCOR2,CSF1,HS3ST2,SRPK3,RASGRP2,F5,AFF2,CSDC2,GNAL,ICA1,PACRG,MBNL1,ADAM11,MGAT3,NF1,NTRK3,OGG1,P2RX7,SUSD4,KHDRBS2,ZMAT4,SCN2B,SNAP25,SOX15,NFASC,ATP10B,SYP,SYT5,TRIM2,DOCK9,THRA,GAN" Drug 4847_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "TRMT9B,BIN1,SEMA7A,ATP1A3,SLC4A4,ALDH7A1,ADAM23,AZGP1,BACH1,MTMR3,DLGAP1,PLAA,SULT4A1,HAPLN1,AATK,RIMS2,RCAN1,PLXNC1,CDKL3,ZNF44,SIGLEC8,GLYR1,TOX3,GRM8,TJAP1,KHK,ADAM22,NEFM,GDPD2,C1orf54,NLGN1,SLC11A1,ZC3H13,SS18,CHST8,TK2,TNS1,CHST5,SLC30A3,DPF3" Drug 1473_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG2,ADORA2A,AMPD3,APBA2,APC,MARK4,ST3GAL5,BAIAP3,ARHGAP33,CRLF1,WHRN,COL4A5,GREB1,TMCC2,SHANK1,EDNRA,CELSR3,STX2,ZNF44,IL6ST,KIT,NACA,NF1,CNOT4,POLG,CCDC40,KCTD17,PPP4R3A,SLC11A1,MAPKBP1,PBLD,SYT5,CRTC1,CHST8,AP4E1,FLRT2,MAP3K12,NT5M,KCNAB1,RNF170" Drug 7222_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASPHD1,SEMA4G,MARK4,ST3GAL5,SLIT2,VAX2,WHRN,HAPLN1,CSF1,ARHGEF10,RIMS2,JAKMIP2,PHF20L1,FGFR3,FLNC,GALC,POLL,ELOVL5,HNMT,KCNH2,LIG4,KITLG,MITF,NFYA,NNAT,PRODH,ZSCAN32,RGS12,SH3BP2,CNKSR2,SYBU,EPN2,IQSEC2,ATP10B,EXOC7,SYNE1,OBSL1,PCDHA6,ZNF24,ZNF74" Drug 366_DN Gleevec; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AK2,C1QTNF3,BIN1,AMT,ANK2,SLC4A4,MTMR3,CALB1,DLGAP1,CPS1,ARHGEF10,GREB1,KLHL3,RCAN1,DTNA,EGFR,MBNL2,STX2,RASL10A,LUZP2,SOX21,VSIG4,AFF1,ADAM22,NPR2,NTRK3,PDE4D,STRN3,SDK2,PTPRD,GAL3ST4,RNASEL,SLC8A1,KBTBD4,SNAP25,ZC3H13,NXT2,TBL1X,TPM1,MARCH8" Drug 5782_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADORA2A,ABCD2,FGD2,APAF1,BCAS1,KIF1A,MTMR3,GYG2,CLDN10,MAGI1,TAOK2,PICK1,WHRN,CRY2,CSNK1E,IPCEF1,EDN1,APC2,CORO2B,FGF1,AFF2,DCTN2,PRELID3A,GPR162,ADAMTS13,PADI2,ELOVL5,KCNF1,KITLG,TAGLN3,NPR2,OPRL1,PTCH1,KLHDC8A,DZIP1,SNCA,KIAA1107,KCNK12,ZNF711,REEP1" Drug 6336_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASPHD1,ADRA1D,MTUS1,BIN1,PPP4R4,MARK4,CFLAR,SYNJ2,PLAA,AKAP5,SH2B1,CSF1R,CNTNAP2,MYEF2,DTNA,COQ7,DLC1,ST3GAL6,FGF1,ALDH1L1,GCNT2,GLYR1,SPACA9,SCIN,INPP5B,ADAM22,PPP2R2B,SNRK,PTPRH,FAM184A,CRTAC1,TCP11L1,PEX26,IFT122,KDM4B,TACR1,TRIM2,LMF1,XRCC4,KCNAB1" Drug 7338_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,ALCAM,CDC42BPA,CDK13,CFLAR,LRIG1,CTH,MED12,COQ7,STX2,KAT8,SEMA4D,AHDC1,COPS8,GLYR1,MSL3,GPD2,RNFT2,INPP5B,KCNF1,KCNH2,MMP16,MPP2,NEK1,OXTR,PRKAR1B,ELOVL2,GSTCD,NEK11,EPN2,BTBD7,KIAA0930,SZT2,VIPR2,MAP3K12,EMSY,DNALI1,HPS4,ST7,SMIM8" Drug 6002_DN Iobenguane sulfate; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "APBB2,FAM131A,BCL7A,SCAPER,C5,CBFA2T2,CREM,PDE4DIP,FAM169A,CTH,DCAF8,MFAP3L,LYPD1,SGSM2,CDON,OPTN,DENND4A,VPS26C,ANKMY1,ACSL4,ZNF589,ATP2C1,MSL3,GRB10,LYRM9,NF1,SLC11A2,LRP12,PRODH,FBXW7,ZNF821,ANKRD6,BTBD7,ZSWIM8,SPTAN1,TTBK2,TFIP11,GDPD5,PCBP4,MPPE1" Drug 7249_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BIN1,APBB2,ARRB2,PTBP2,RUNX1T1,ARHGEF2,SRSF11,NRXN3,RUSC2,SGSM2,TENM1,DENND4A,ZNF549,ZNF589,FGFR1,MSL3,HNMT,IFI16,INPP5B,MX1,NF1,NFYA,NOVA1,PDE4D,STRN3,MAPK7,TMEM231,ROGDI,REV3L,RGS4,TMCC1,THSD1,SEPT8,SLC35G2,CABIN1,UBE3A,ZBTB14,ZNF189,NT5M,PDSS2" Drug 1784_UP Aconitine [302-27-2]; Up 200; 6.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG2,C1QTNF3,MYRF,RUNX1T1,CHN2,EPS15L1,IQCK,SPOCK2,KIAA0753,DPH1,RASGRP2,VPS26C,POMT1,GAA,DISC1,ARFIP1,BTN2A1,PADI2,TJAP1,KCNN1,NTRK3,OGG1,PDE4D,PTK2,RAD51D,RGS12,C12orf49,ATXN2,FAM102A,SLC11A1,SLC12A2,THSD1,SEPT8,PDLIM2,OBSL1,CBX5,TNS1,LAT2,HPS4,UBE3B" Drug 6075_DN Delsoline [509-18-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ALCAM,AMT,APBA2,KCNAB2,PPFIA3,CACNA1I,CA4,CAMK2B,PLEKHB1,SLC4A8,BAG4,CSF1R,LRIG1,PDE4DIP,TMCC2,DNM1,DUSP9,BAIAP2,SYT17,ALDH1L1,GCNT2,POLL,NF1,PDE4B,MAPK7,PRODH,PTN,PTPRE,RAD51D,SEC14L1,SH3BP2,SNCA,KDM4C,KANK1,PARD3,CABIN1,TPM1,HIRA,VGF,VIPR2" Drug 3440_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADRA1D,EPB41L5,FAM131A,MARK4,CA12,SCARB1,UBE2L6,VAX2,SH2B1,CSNK1E,DBT,DTNA,MRNIP,ANKMY1,FHL1,FAM49B,CNTRL,IL6ST,MAP4,MPP2,ADAM22,NPTX1,SLC25A23,STRN3,PRKAR1B,PRPH,CNNM2,CCDC25,ABLIM3,BTBD7,KDM4B,ZHX3,TSPYL2,CAMTA2,DIP2A,STX1A,NSD1,SLC44A1,CABIN1,CDK20" Drug 6791_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,ADRA1B,AMPD3,MARK4,ST3GAL5,BAIAP3,CA4,HAP1,CHRNA4,SULT4A1,CNTFR,RUSC2,REEP2,FHL1,FLNC,CNTRL,IRF8,MEF2C,MMP17,ZNF862,MYT1,NPTX2,SLC25A23,POU6F1,CEP41,PRKAR1B,C1orf54,RFX2,EMID1,AMBRA1,CNKSR2,DZIP1,FAM214B,SNCA,ZSWIM8,SPTB,PLCB1,TAL1,FAM189A1,LAT2" Drug 6982_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ALCAM,AMH,BCAS1,RGS20,CFLAR,PROM1,CRLF1,CNOT8,TPP1,VAX2,ARHGEF10,CTH,ENO2,KAT8,ERAP1,INPP5K,AHDC1,GFER,ICA1,TJAP1,MAP4,MIA2,MPP2,ZNF862,PALM,PDE4A,TMEM104,ZSCAN32,ZSCAN2,RGS12,SBF1,PKNOX2,ZKSCAN3,COA1,NXT2,ASTN2,TK2,TPM1,CHST5,REEP1" Drug 3626_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AMT,APAF1,N4BP2L1,AZGP1,RGS11,MYRF,LDLRAD4,CAMK2B,DLGAP2,CSF1,VCAN,ZNF804A,FAM13A,PLXNC1,TENM1,ERCC2,PIPOX,NEU3,GNAL,GRB10,INPP5B,KCNH2,LAMA2,TAGLN3,MYT1,NELL2,PCDH9,TMOD2,PPARA,CEP41,MASP1,C1orf54,RGS4,EMID1,ZFP2,PDZD2,IQCE,DOCK9,ICAM5,CHST5" Drug 380_UP tamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG3,BIN1,N4BP2L1,MTMR3,ARHGAP33,DLGAP1,CACNA2D2,ARHGEF4,C2CD2L,TNK2,MRNIP,PDLIM5,RASL10A,FYN,TRAF3IP2,BTN2A1,PTPRT,MAP4K5,NXPH3,L1CAM,MPP2,PALM,POLG,RAD51D,RNASEL,RYR3,SATB1,ZNF821,SH3BP2,FAM102A,KBTBD4,GLT8D1,ZBTB43,LMO3,CLSTN2,TACR1,TBL1X,SZT2,SMUG1,UBE3B" Drug 2341_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADORA2A,ARRB1,C5,CFAP410,CD38,SULT4A1,CNTN1,CREM,CRY2,KIAA0753,CELSR3,MTSS1L,SRCAP,FERMT2,GPD2,LILRA2,KHK,KIF5A,MAP4,MYCN,NF1,NINJ2,P2RY1,NECAB2,NEK11,SH3BP2,KDM4B,DOK5,ZSWIM8,IQSEC2,DDN,ATP10B,CLSTN2,SYT5,EXOC7,CDK20,TRO,XRCC4,TRIM9,MAP3K12" Drug 6508_DN Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADRA1D,MTUS1,TRMT9B,CDC14B,PDE8B,CFLAR,SGCE,MAGI1,CACNA2D2,NRG2,NCOR1,PDE4DIP,DZIP3,ARHGAP24,DCAF8,JAKMIP2,EGFR,COQ7,MTSS1L,VPS26C,HSF2,INPP5B,MAPT,GIT1,LYRM9,NNAT,PLEC,PRKAR1B,PTN,ZDHHC14,ZC3H14,SLC6A8,CXXC4,CDK19,ASTN2,TK2,KCNK12,ZNF45,EMSY,URM1" Drug 1890_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "APBB2,KRIT1,QKI,FBXL5,DDX46,ACOT8,MAMLD1,KCTD3,EPB41L2,FGFR1,SEC23B,GRIK5,CLASRP,MAP4K5,LAMP2,MKLN1,NUCB2,OPA1,PDE1C,POLG,EXD2,CASC3,FBXO11,ABLIM3,SLC11A1,SLC22A4,ZKSCAN3,DOP1A,PEG10,ATP10B,LARP4,DIP2A,TBL1X,DOCK9,DICER1,HIRA,UBE2H,CLDND1,EVI5,MARCH8" Drug 451_DN TTNPB; Down 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDC42BPA,SEMA7A,SLC4A4,ATP2B2,ATP6V0A1,BAIAP3,HAP1,SCARB1,CHGB,CSF1,RIMS2,GIT2,RHOBTB1,FEM1B,CELSR3,SUGP2,MBNL2,RGS17,KAT8,SARAF,OGA,PRRC2B,BTN2A1,FAM107A,MAN1B1,ICA1,LAMA2,MEF2C,MT1M,MYO7A,NPY,MBOAT7,NUDT11,ATXN2,ARHGEF40,SMARCD3,MAPKBP1,SYN1,NDRG4,AAAS" Drug 5497_DN Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ABR,AP2A2,CDC42BPA,SCAPER,MAGI1,RAB28,DCAF8,KIAA0753,RCAN1,EDNRA,EPB41L2,FHL1,GAD1,INPP5K,CRCP,POLL,MAP4,SCAMP5,LYRM9,NFYA,OGG1,SLC25A23,FSD1,TMEM104,NKAIN1,RGS12,SH3BGR,BTBD7,TMCC1,RBM34,ERC1,ZNF34,THRA,TK2,CABIN1,CDK20,KLC2,HPS4,MPPE1,KAT6A" Drug 6262_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "APBB2,PDE8B,CFLAR,SCAPER,GYG2,RCBTB2,CHRNA4,VAX2,QKI,CSF1R,ARHGEF4,CNNM1,EGFR,RASGRP2,FGF12,SEMA4D,NEU3,SRCAP,TXNL4A,GLYR1,GRIK5,HAS2,ATXN2L,IL6ST,MGAT3,ADAM22,NF1,SLC11A2,RETREG1,PLCD1,SAMD9,PTCH1,ATP10B,PHLDB1,PLCB1,CABIN1,TRPM2,FAM155A,PHTF2,TIGD6" Drug 5824_DN Meropenem [96036-03-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADD1,ADRA1D,MADD,MARK4,SPAG9,CBFA2T2,NRG2,MED12,FEM1B,SUGP2,CINP,TRAF3IP2,DISC1,FICD,HNMT,INPP5B,MITF,MT1M,NEK1,NFYA,PIK3R1,KCTD15,PLCD1,ZNF426,LRP12,MAPK7,SAMD9,TMEM231,RGS4,BTBD7,SMARCA4,PDZD2,TSPYL2,TNS2,TIAM1,BHLHB9,METTL3,LMF1,ZNF24,SMIM8" Drug 1386_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ARNTL,CDK13,MARCH3,CFLAR,BMP7,CAPN3,RUNX1T1,CHN2,RAB26,AKAP6,ENTPD4,VCAN,PPP6R2,ZNF337,TM9SF4,DBI,DPH1,RCAN1,FGF1,BAIAP2,CINP,RUNDC3A,GNG4,GPR12,KHK,MAP4,GIT1,NTRK3,SETD4,PTPRE,CCDC40,RGS12,KBTBD4,SMARCA4,ZHX3,ZSWIM8,THRA,NACC2,XRCC4,EVI5" Drug 2470_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADORA1,BIN1,DDO,ARHGDIG,KIF1A,PROM1,BMP7,CACNA1G,CFAP410,HAP1,CBFA2T2,SRSF11,TAOK2,SULT4A1,RAB26,DCAF4,C2CD2L,SEZ6L2,HEYL,RASGRP2,STX2,APC2,HPCAL4,GFER,PCDH17,ADAMTS13,GRIK5,IL6ST,MAP4,TAGLN3,ZNF862,NEFM,PMP22,RIPOR1,DOP1A,TACR1,TNS2,TIAM1,LMF1,PLSCR4" Drug 5725_DN Ricinine [524-40-3]; Down 200; 24.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "RALGAPA1,AP2A2,BIN1,ALDH7A1,CA8,B4GALT6,SULT4A1,HAPLN1,PARD6A,EIF4G2,CINP,CSPG5,OGA,FYN,ERAP1,GPD2,TDRKH,LIFR,MAPT,NPR2,CCSER2,GRAMD1C,SH3TC2,RPS6KA2,SBF1,SH3BP2,ASAP3,FUZ,SNCA,SS18,SZT2,CHST8,TIAM1,UGT8,WIPF1,KLC2,XRCC4,KCNAB1,MPPE1,ACTR3B" Drug 7298_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "APBB2,CDK13,RGS9,SYNJ2,CACNA1A,USP2,MTMR7,PLEKHB1,CREM,HAPLN1,HDAC9,MFAP3L,SPOCK3,HS3ST2,EDNRA,EGFR,AASS,MTSS1L,DENND4A,REEP2,PRUNE2,LPAR4,GRM8,TJAP1,MAPT,PRPH,RGS12,ST6GAL1,ARHGEF40,SLC9A5,TSPYL2,ASTN2,RPGRIP1L,PHF24,NSD1,TIAM1,TNS1,WIPF1,TFIP11,KCNAB1" Drug 1603_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG3,C1QTNF1,GAS7,ARNTL,BMP7,MTMR2,CD86,FOXN3,ARHGEF10,PPP1R16B,DTNA,EEF1D,SRPK3,ENO2,RASGRP2,RABEPK,VPS26C,EZH1,TRMO,SRCAP,PRDM5,MUM1,IDH3A,IL6R,MAP4,GIT1,NELL2,NTRK3,PDE4B,FAM214B,SLC6A8,MAPKBP1,TMCC1,KDM4B,STX1A,TBL1X,TCF4,SMUG1,GDPD5,IFT88" Drug 3764_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADD2,C1QTNF3,BEGAIN,BCAS1,CDC14B,FUBP1,LDLRAD4,CAPN3,RHBDL1,LDB2,CHRNA4,SULT4A1,CNTFR,FAM149A,CSF1,DTNA,HEYL,PLXNC1,NCALD,ST3GAL6,FYB1,SIGLEC8,ALDH1L1,PCDH17,GNAL,GNG4,GRM2,SOX21,NXPH3,ATXN2L,C2orf72,MAN2A2,C19orf57,PSD,RGS12,CNKSR2,SLC9A5,ATP10B,TUBB1,EVI5" Drug 6495_DN Methylatropine nitrate [52-88-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BRAP,DOC2A,FAM131A,APOC1,BCAS1,CDK10,CFLAR,SCAPER,B4GALT6,PDE4DIP,DZIP3,GIT2,ZNF804A,C2CD2L,PARD6A,EGFR,STX2,EZH1,SEPT9,INPP5K,MALT1,KIF2A,MIA2,MPP2,NEK1,OGG1,PRODH,RIPOR1,SAFB,ZNF821,SIRT2,CAMTA2,STX1A,NSFL1C,COBL,EXOC7,KIAA0930,CHST8,HPS4,EPM2A" Drug 5975_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AP2A2,C1QTNF3,ALK,APBA2,APBB2,GAS7,PPP4R4,CAMK2G,CBFA2T2,BAG4,NCOR2,PDE4DIP,ARHGEF4,USP6NL,MFAP3L,RASGRP2,PRELID3A,GAD1,GALC,INPP5B,KCNH2,NPR2,PCBP3,MAPK7,DCUN1D2,FERMT1,OGDHL,LIMCH1,DOP1A,ZNF423,ST5,JMJD6,WSCD1,KIAA0930,PARD3,ZKSCAN5,VAV1,LAMP5,ITM2C,KAT6A" Drug 4659_UP Equilin [474-86-2]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "SYN3,ADGRB2,CACNA2D1,MTMR7,DLGAP1,AKAP5,CRMP1,ARHGAP24,MYEF2,MFAP3L,C2CD2L,PLPPR4,HS3ST2,TOM1,MBNL2,SRPK3,MTSS1L,ERBB4,APC2,AGAP2,SIGLEC8,NEU3,GLI2,GPR75,GNAL,GRM8,BACH2,ELOVL5,P2RX7,PDE4A,PPP2R2B,RFX2,RGS12,EMID1,NLGN1,KANSL3,SLC9A5,PCDHGB6,REEP1,KCNAB1" Drug 7439_UP Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "LTBP4,PPFIA3,MPDZ,BCL7A,SCAPER,WHRN,FAM169A,PPP6R2,DAPK3,C2CD2L,TOM1,ING4,MRNIP,FGFR3,TRAF3IP2,ALDH1L1,LPAR4,CACFD1,ITPKB,MAP4,NPTX1,SETD4,PALM,NLE1,PRPH,RIPOR1,KCTD17,EMID1,SBF1,EPN2,SLC11A1,BTBD7,SMARCC2,TSNAXIP1,ZHX3,ZSWIM8,ASTN2,FAM208A,DMXL2,SLC30A3" Drug 3032_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "SPARCL1,SYT13,APBA2,PPFIA3,RGS11,MYRF,BAIAP3,HIP1R,SEPT7,CHGB,SOCS6,NCOR2,CNTNAP2,RIMS2,SNPH,MFAP3L,DMD,SRPK3,NCALD,SIGLEC8,ALDH1L1,GNG4,GPR37,PCLO,AP4S1,SCIN,LAMA2,MX1,MYCN,OPRL1,MAPK7,PTPN13,PTPRB,RGS12,CCDC92,EPN2,SLC11A1,DOCK9,LMF1,PLSCR4" Drug 2139_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "BIN1,CASK,ARRB1,ADGRB1,BMP7,USP2,CABP1,CREM,CSNK1E,CNTNAP2,RUSC2,EDIL3,STX2,PDLIM5,CAMKK2,FYB1,GALC,ALDH1L1,GCNT2,GPD1,LILRA2,TJAP1,MAP4,ZNF862,PCDH9,MTRF1L,KLK6,PTPN13,RIPOR1,PID1,SBF1,STUM,FRMPD1,PKNOX2,SNCA,CDK19,CEP68,TBCEL,SLC35G2,HIF3A" Drug 2408_UP Disopyramide [3737-09-5]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ARNTL,ATP2A2,KIF1A,CACNA1I,SEPT7,HOMER3,PCYT1B,FAM149A,DGKG,SPOCK3,DTNA,TNK2,ERBB2,FGFR1,PDLIM5,GUCY1B1,KCNJ5,MAP4,MMP16,MYCN,NEK1,PDE4A,PLCD1,PPARA,RGS3,RGS12,NUDT11,CLIP1,PPM1E,PEX26,TMCC1,RBM26,CLSTN2,SS18,PDLIM2,TBL1X,CRTC1,TPM1,AMACR,NLRP3" Drug 5471_UP Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADCY6,AGT,ALDH7A1,RCBTB2,SULT4A1,FHL5,CNTN1,CNTNAP2,JAKMIP2,FGFR1,FYB1,GNAO1,ICA1,KCNH2,KCNN2,LMO2,MMP16,PRKAR1B,ZSCAN32,SUGCT,SALL1,ZNF821,ABLIM3,SLC2A5,PKNOX2,ELMO2,BTBD7,LIMCH1,PDZD2,SYN2,SYT5,TACR1,RPGRIP1L,PCDHGA10,CRTC1,LMF1,SPHK2,MAP3K12,HRASLS,JPH3" Drug 3059_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADCY6,MTUS1,SEMA6A,ANK2,BMP7,CRLF1,RAB26,HAPLN1,MFAP3L,C2CD2L,HEYL,EPB41,FAM198B,AFF2,CHL1,SRCAP,GLI2,GRIK5,GRIN2C,IL6ST,NOVA2,NTRK3,OXTR,MAPK7,RELN,BCAS3,PTH1R,PTPRH,GAL3ST4,SEMA6D,SH3GL3,SOX15,HECW1,TACR1,SMG6,PHF24,HIF3A,AP4E1,TIAM1,ZNF154" Drug 1679_UP Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "OSBPL1A,APBB2,MARK4,ADAM23,RAB28,HOMER3,BAG4,CSF1,GPRASP1,SGSM2,CDON,DTNA,NCALD,SEMA4D,CGREF1,MALT1,SPACA9,INPP5B,KHK,MAP4,MBP,MKLN1,MMP16,ZNF862,NF1,NTRK2,NLE1,ELOVL2,FNDC3A,SPTAN1,CDK19,ZBTB43,NXT2,PLCB1,TRIM2,AP4E1,ZNF34,VIPR2,REEP1,PHTF2" Drug 4378_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ALK,TRMT9B,GAS7,APOC1,CDK13,AZGP1,CFLAR,MTMR3,HIP1R,KCNAB3,SULT4A1,ENTPD4,EXOG,DTNA,TENM1,F5,FGF1,FLNC,NEU3,NXPH3,KCNN1,KPNA5,MEIS1,ADAM22,NPTX2,OGG1,PDE1C,PFKFB2,GDPD2,PTPRO,PNMA8A,EMID1,STUM,SLC2A5,BTBD7,SNAP25,TBCEL,LAT2,PRDM10,KCNAB1" Drug 2642_DN Bisoprolol fumarate; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AK2,BIN1,PPFIA3,CDC14B,ARHGDIG,MTMR2,QKI,DCAF8,GIT2,FBXL5,LYPD1,KAT8,BAIAP2,AGAP2,POLL,BTN2A1,HNMT,HSF2,GIT1,NFYA,CNOT4,SLC11A2,RETREG1,FSD1,PRKAR1B,NKAIN1,RAD51D,ZDHHC14,RGS3,ROBO1,ZNF821,ABLIM3,ZBTB43,NXT2,MCF2L,TCF12,NSD1,TPM1,XRCC4,ZNF189" Drug 2747_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "NDRG2,APLP1,APOC1,CDK13,ST3GAL5,CACNA1G,CACNA2D1,HAP1,CBFA2T2,RCBTB2,LHX2,LY86,HOMER3,WHRN,SNCAIP,CSF1R,CSNK1E,PARD6A,SHANK1,EGFR,GCNT2,POLL,ATXN2L,KCNH2,NF1,NPR2,CLDN11,CDK18,PRKAR1B,PRKCB,ZNF493,ZDHHC14,SEMA6D,KDM4C,PEG10,ARC,TBCEL,CHST8,WIPF1,KAT6A" Drug 5879_DN Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDC42BPA,KCNAB2,ADAM15,MPDZ,TAOK2,NRG2,CNTNAP2,PPP6R2,DBT,MRNIP,COQ7,ANKMY1,FGFR1,INPP5K,ZNF276,HSF2,MAPT,MBD1,TAGLN3,ZNF862,SLC11A2,KCTD15,PPP3CC,SNRK,ELOVL2,AMBRA1,KBTBD4,CDK5RAP2,LIMCH1,SPATA7,ZBTB43,POGZ,NXT2,VPS13A,PARD3,TRIO,PLPPR2,XRCC4,MAP3K12,KAT6A" Drug 6521_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "APC,AZGP1,CACNA1I,BAIAP3,CFAP410,CALB2,CDH2,CHRNA4,EPS15L1,NCOR2,SPOCK2,BRINP1,C2CD2L,FCF1,EGR3,AASS,IRAK4,GFER,GPER1,GRB10,RASSF8,JAK2,KCNN1,LAMA2,NOVA2,NTRK3,PALM,MTRF1L,PPARA,WDR25,PNMA8A,SEMA6D,MRAS,SGK1,SLC8A1,SNAP25,TNS2,WIPF1,CLIP2,SLC30A3" Drug 6814_DN Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASPHD1,AK2,CDC42BPA,ARHGDIG,MARK4,ADAM15,BMP7,TAOK2,AKAP7,CSF1R,SOCS5,MFAP3L,CNNM1,NCALD,CDKL3,EZH1,ZNF589,FAM49B,INPP5K,HSF2,KCNH2,GIT1,STRN3,PRKAR1B,PRPH,GSTCD,SAFB,SLC9A5,KDM4C,SPTAN1,ST5,TTBK2,EXOC7,IQCE,KIAA0930,CRTC1,ZNF34,PLPPR2,EPM2A,PHTF2" Drug 4346_DN (S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADRA1D,NME5,APBA2,CFLAR,CACNA1I,BAIAP3,LRRFIP1,FOXN3,QKI,PICK1,WHRN,CSF1,PPP6R2,MFAP3L,ING4,TNK2,VPS13B,FER,BAIAP2,ALDH1L1,GRIK5,ATXN2L,IL6ST,KHK,MID1,GIT1,LYRM9,NEK1,NPR2,NPTX1,PLXNB1,ELOVL2,PTN,ZSCAN32,ZFHX4,SAFB,TSNAXIP1,CLSTN2,WSCD1,KCNK12" Drug 5068_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "TRMT9B,BIN1,EPB41L5,BACH1,SYNJ1,FOXN3,ARMC8,NRG2,ARHGEF4,MFAP3L,CHRDL1,EXOG,EDIL3,MBNL2,STX2,ZNF549,TDRKH,MUM1,IL6ST,MEF2C,NF1,PRKAB2,MAPK3,ELOVL2,ZSCAN2,CEP97,GAL3ST4,SUPT20H,ZFP30,SLC4A3,PPP4R3A,IQSEC2,CEP68,ASTN2,TK2,RIMBP2,METTL3,OSBP2,LAT2,EVI5" Drug 5988_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ABHD6,LTBP4,GAS7,CFLAR,BAIAP3,CACNA2D2,FAM189A2,QKI,WHRN,PDE4DIP,RIMS2,DTNA,PLXNC1,FGFR3,TMEM8B,SIGLEC8,SRCAP,HNMT,KCNJ5,MSI1,NF1,MTRF1L,PPP2R2B,MAPK7,MAPK10,PTPRO,RFX2,OGDHL,SNCA,KDM4C,ATP10B,PHLDB1,PLCB1,ZEB1,PCDHGA10,AP4E1,TK2,RUNDC3B,ZNF74,TIGD6" Drug 6806_DN Cyproterone acetate [427-51-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ABHD6,CDC42BPA,CDC14B,ARRB1,ARRB2,PLA2G4C,RIPK1,SYNJ2,LHX2,RCHY1,MFAP3L,PARD6A,EZH1,ZNF589,FECH,FHL1,INPP5K,GPD2,CNTRL,MAP4K5,PCDH9,PPP5C,PRKAR1B,TMEM104,RPS6KA2,ZFP30,FERMT1,CHD9,ZKSCAN3,UHRF1BP1L,UNC5B,TROVE2,NXT2,SYT1,ASTN2,TMEM121,CHST8,ZNF24,MFF,EPM2A" Drug 6608_UP Nifurtimox [23256-30-6]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ADD2,C1QTNF3,ATP1A3,SYNJ1,BAIAP3,KALRN,CSF1R,VCAN,CHRDL1,ZNF391,F5,REEP2,FGF1,PRELID3A,NEU3,SRCAP,LYVE1,ATXN2L,IL12A,ITGA7,MAP4,NPY,PALM,PPP2R2B,PRKAR1B,PRPH,PTN,PTPRB,CCDC40,C1orf54,ASAP3,CNKSR2,SNCA,CDK19,OBSL1,PCDHA5,TRIO,VIPR2,KCNAB1,GAN" Drug 6569_DN 5155877; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "C1QTNF3,APBB2,SEMA4G,RIPK1,CFAP410,CCNT1,LHX2,ABI3BP,NRG2,SOCS5,CNTNAP2,SLITRK5,SPOCK2,DTNA,APH1A,ETV1,B4GALNT1,HTATSF1,MBD1,MN1,NDP,NFYA,NPR2,OGG1,PDE1C,FSD1,SH3BP2,CNKSR2,LIMS2,KDM4D,SIRT2,SPTAN1,PBLD,TK2,HIRA,WIPF1,HPS4,NAV3,KCNAB1,KAT6A" Drug 3451_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASIC1,C1QTNF3,AMT,CDC14B,ATP6V0A1,KSR1,CACNA1A,ARHGEF2,SRSF11,PICK1,SLC4A8,ENTPD4,NCOR1,DTNA,SCARA3,GABRG2,ADAM28,MAP4,MATK,TM6SF1,ZNF862,PCDH9,CDK18,PRKAR1B,PRODH,ZSCAN2,GTDC1,TCP11L1,RPS6KA2,ASAP3,SMARCD3,VPS13A,SYT5,CABIN1,VGF,VIPR2,VLDLR,GDPD5,KCNAB1,MPPE1" Drug 6484_UP Urosiol [128-13-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AK2,ARHGDIG,N4BP2L1,RIPK1,SYNJ1,CFAP410,CAMK2G,RUNX1T1,DCAF4,ARMCX2,RUSC2,HS3ST2,ST3GAL6,DCTN2,EFCAB2,GCNT2,LYVE1,ZNF276,POLL,PCLO,SLC2A6,HAS2,HLF,HSF2,INPP5B,MATK,ADAM22,PPP5C,PRKCB,KCTD17,MRAS,PPP4R3A,ELMO2,SNAP25,SNCA,ASTN2,TRIM2,LMF1,SLC30A3,SEMA3B" Drug 6696_DN Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "CDC42BPA,APC,PPFIA3,ALDH7A1,ST3GAL5,CFAP410,SYNGR3,NRXN3,STOML1,PICK1,ARMCX2,SPATA2,MRNIP,AFF2,FYB1,TRAF3IP2,INPP5B,KCNN1,MGAT3,NF1,PFKFB2,RETREG1,PLCD1,ZSCAN2,PID1,TRAPPC13,FAM102A,ASAP3,FBXO11,WSCD1,DOCK9,TMEM121,TK2,HIRA,OSBP2,XRCC4,MAP3K12,KCNAB1,TIGD6,DPF3" Drug 4636_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "TRMT9B,AMH,AMT,PDE8B,ADGRB2,BAIAP3,SCARB1,LARGE1,AKAP7,MFAP3L,HEYL,ING4,ANKMY1,NRN1,ST3GAL6,CGREF1,HTATSF1,CACFD1,DHX35,KCNF1,MT1M,MYT1,NNAT,PIK3R1,PRKAR1B,PTPRB,TMEM231,SCN2B,FRMPD1,MYH15,ZBTB43,KIAA1107,TCF4,ZNF34,TIAM1,RIMBP2,TPM2,EVI5,KCNAB1,EPM2A" Drug 3307_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "AP2A2,ALCAM,LTBP4,APBB2,GAS7,APOC1,ARRB1,MARK4,NCOA1,SYNJ2,ARHGEF2,PLEKHB1,PDE4DIP,CTH,DTNA,FEM1B,VPS13B,FHL1,CGREF1,ERAP1,GLYR1,GPER1,HNMT,SCAMP5,NEK1,NF1,NPTX1,RNASEL,FBXW7,PEX26,SPART,LHPP,PHLDB1,EXOC7,TRIM2,TMPO,CABIN1,VGF,XRCC4,ZBTB14" Drug 2883_DN Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ALCAM,AMPD2,EP400,BCAS1,CASK,NCOA1,MTMR2,CBR1,CCNT1,HOMER3,RCHY1,SOCS5,DPYSL2,DTNA,CELSR3,ING4,INPP5K,INPP5B,MAP4,TM6SF1,MMP16,PLXNB1,CNNM2,TMEM104,ELOVL2,CEP97,RGS3,FBXW7,MCMBP,FBXO11,SYBU,EPN2,SPTAN1,SYNE2,AGTPBP1,PCDHA6,REEP1,MPPE1,RNF170,SENP7" Drug 6214_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-04 1.00E+00 2.64E-03 2.97E-02 40 199 "ASPHD1,AP2A2,AK2,BIN1,APOC1,KSR1,ARHGEF10,PDE4DIP,TBC1D5,KIAA0586,DAPK3,DNM1,DTNA,MBNL2,EIF4G2,EIF5,FAM49B,DISC1,USP19,GPR75,GNAL,BTN2A1,IFI16,INPP5B,KHK,NEK1,NF1,LRRN3,RNASEL,SGK1,ABLIM3,BTBD7,SLC22A4,DOK5,SPTAN1,JMJD6,EMSY,MPPE1,PLSCR4,UBE3B" Drug CID000010701 2-nitroimidazole Stitch 2.30E-04 1.00E+00 2.65E-03 2.98E-02 29 129 "ADRA1B,ALDH7A1,DMD,DTNA,DTNB,TUBD1,GMPR2,TUBB3,FCGR3A,SEMA4D,B4GALNT1,TUBA8,L1CAM,MX1,SLC11A2,PDE1B,PPARA,MAPK10,AP1AR,SARS,SLC11A1,KLHL4,MGRN1,SYNE1,ARHGAP9,SIRT1,TUBB2A,TUBB1,TUBA1A" Drug 966_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.30E-04 1.00E+00 2.65E-03 2.98E-02 38 186 "ASPHD1,ABHD6,AP2A2,NCOA1,MPDZ,SOCS6,ABCG1,LRIG1,CSNK1E,ABCC5,EGR3,RGS17,STX2,FGFR3,AMOTL2,NOP56,ZNF44,GHR,GPER1,CACFD1,FICD,KHK,MAP4,PIK3R1,RETREG1,SMIM7,STRN3,FA2H,PPP5C,RIC8B,DOP1A,VPS13A,TACC1,BEX4,SSBP2,UBTF,ZNF23,TFIP11" Drug 6286_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.30E-04 1.00E+00 2.65E-03 2.98E-02 38 186 "RALGAPA1,ASPHD1,APC,EPB41L5,CFLAR,SCAPER,IL33,ARHGEF1,ARHGEF2,KCNAB3,QKI,WHRN,CREM,CSNK1E,VCAN,CTH,PITPNC1,LYPD1,ELN,COQ7,RRAGB,FGFR1,GAD1,SIGLEC8,ZNF276,NF1,CNOT4,SMOX,CEP41,PTCH1,SH3BP2,PHLDB1,KIAA1107,TBL1X,TIAM1,NDRG4,NT5M,PHTF2" Drug CID000019390 AC1L2E0P Stitch 2.30E-04 1.00E+00 2.65E-03 2.99E-02 56 307 "C1QTNF3,SPOP,PHF12,NCOA1,DYNLL1,RIPK1,CALM1,RUNX1T1,CCNH,SCARB1,COPB2,NCOR1,NCOR2,HDAC9,GSDME,MED12,ERBB2,GMPR2,KAT8,FHL1,PPARGC1A,LYVE1,BRD8,RAB40B,GPD1,GPD2,KAT7,DDX19B,HNF4G,HP,LMO2,MEST,AFF1,AFDN,PIK3R1,PPARA,MAPK9,MAPK10,RBBP8,RGS3,GSTCD,RORB,ELP2,RXRA,SAFB,SMARCA4,IFT122,TRERF1,MMS19,NSD1,THRA,CBX5,KAT6B,RNF103,KAT6A,AP3B2" Drug ctd:C031180 chrysene CTD 2.33E-04 1.00E+00 2.68E-03 3.02E-02 134 880 "CLK4,SYS1,SPARCL1,LCORL,PPFIA3,CPNE5,CDC14B,ARNTL,EIF4G3,ATP2A2,ATP6V0A1,BCHE,C5,THSD7A,CAPN3,USP2,MAP4K4,AKAP7,ABI3BP,RBM39,AKAP12,GDA,RASGEF1C,GREB1,DCAF4,MYADM,YTHDC1,ELMSAN1,NR1D2,DMTF1,ARRDC4,ABCC5,EDNRB,KLHL5,PHF20L1,KMT5B,EIF4G1,SRPK3,PAN3,EIF1,HSD17B14,EPB41,F5,REEP2,FAM198B,FGFR3,POLK,ZMYND15,TPK1,STAU2,OGA,GABRA3,CPLX2,PCDH17,LYVE1,SPIN1,HTATSF1,CCDC184,GRB10,DIDO1,PLCD4,SERP2,FAM107A,SLC2A6,RASSF8,NXPH3,HLF,CPT1C,CELF5,ICA1,ITGA7,ASPRV1,MAT2A,MEF2C,KITLG,BLOC1S2,MSR1,NRBP2,THYN1,SFR1,NRCAM,P2RX7,PDE4A,PFKFB3,ABCB1,KCTD15,PLCD1,PMP22,CEP41,PKIA,LAMA1,MTMR10,PTPRB,PTPRG,TUG1,RGS12,CCDC82,ROBO1,MEG3,HUNK,NCBP3,SMPD3,SH3BGR,SHC4,DZIP1,SLC8A1,ARHGEF40,SPP1,ZNF423,CLSTN2,SEPT3,NSFL1C,SYNE2,PLCB1,COBL,ANKRD12,MLST8,PCDHGA9,NSD1,PCDHAC2,GPRIN3,SLC35G2,DICER1,ZMAT3,RASD2,ZNF346,CA14,REEP1,RGS7BP,FAM13C,TTC7A,NHSL1,AAAS,CPNE4" Drug 2833_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "APC,CDK10,NUMB,SYNJ2,MTMR2,CAMK2G,B4GALT6,RAB28,CLCN3,QKI,SLC4A8,DZIP3,TBC1D5,PDLIM5,CGREF1,SRCAP,GLYR1,CNTRL,MAP4,ADAM22,RETREG1,SLC25A23,STRN3,PRPH,WDR25,ELOVL2,SLC25A36,SEC14L1,TRA2B,SYBU,SIRT2,USP33,ZBTB43,THSD1,ASTN2,TMPO,VGF,ZNF45,MPPE1" Drug 3221_DN Metergoline [17692-51-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "ADORA1,AK2,BIN1,ARHGDIG,RGS20,RIPK1,SOCS6,EPS15L1,VAX2,HOMER3,CSF1,PARD6A,IRAK4,STX2,VPS26C,SEPT9,GRM8,ATXN2L,HNMT,INPP5B,KCNQ3,LMO2,KITLG,ZNF862,OGG1,PCDH9,RGS12,EMID1,RASA3,ASAP3,NLGN1,PKNOX2,BTBD7,KDM4C,TROVE2,PLCB1,PCDHA5,VGF,REEP1" Drug 6956_DN LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "ABHD6,AK2,PPFIA3,KIF1A,MPDZ,SLC25A14,SYNGR3,HOMER3,SMARCAL1,PPP6R2,DAPK3,MFAP3L,FBXL5,EXOG,MRNIP,FGFR3,FHL1,EFCAB2,FAM49B,MALT1,GRM8,RNFT2,ATXN2L,NF1,OGG1,OPA1,PCDH9,FA2H,TMEM104,RIPOR1,FERMT1,PPP4R3A,EPN2,SEPT8,JMJD6,LMF1,WRN,NDRG4,REEP1" Drug 4978_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "NDRG2,ADD1,AGT,PPFIA3,SEMA4G,ARRB1,CDK13,CALB2,EPS15L1,HOMER3,ARHGEF6,ARHGEF10,EDNRA,ZNF589,GPER1,PCLO,HSF2,MAP4,MMP16,NOVA2,TRHDE,PPARA,ELOVL2,ZMAT4,CARF,FUZ,ST6GAL1,SNCA,KDM4B,IQSEC2,NXT2,PCDHGA10,PCDHA5,CABIN1,TRIO,HIRA,LAT2,EMSY,ADAMTSL3" Drug 2930_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "PPFIA4,APBB2,CASK,ARRB1,MARK4,ADAM15,SYNJ2,CAMK2G,CAPN3,SCARB1,HDAC9,E2F5,EIF1,CDKL3,NOP56,ERAP1,ADAM28,PADI2,IL6R,KPNA5,MATK,MEST,NFYA,OGG1,OPA1,KCTD15,ZSCAN32,RASA3,PPM1E,DZIP1,MYH15,STX1A,KANK1,PDLIM2,NSD1,R3HDM1,TPM2,HSPBP1,UBTF" Drug 4225_DN Carcinine [56897-53-1]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "TRMT9B,APC,APOC1,CDK10,SEMA4G,CDK13,NCOA1,ADGRB2,ST3GAL5,SCARB1,B4GALT6,LHX2,NRG2,EGFR,MTSS1L,ST3GAL6,SCARA3,SEPT9,RUNDC3A,ZNF276,CRCP,LPAR4,HSF2,PPARA,PRKAR1B,MAPK7,GRAMD1C,KCTD17,PPP4R3A,KANSL3,ZNF667,ZBTB43,CEP68,TIAM1,CABIN1,AMACR,OSBP2,XRCC4,KCNAB1" Drug 6981_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "AP2A2,TRMT9B,AMPD3,FAM131A,ST3GAL5,SYNJ2,ARHGEF6,AKAP7,CRMP1,CRY2,CSNK1E,CTH,DBN1,MFAP3L,DTNA,HIPK3,EIF4G2,ENO2,ZNF549,FECH,FHL1,DISC1,TDRKH,KCNB1,KIFC3,MAPT,ZNF862,NF1,NPTX1,PFKFB2,C1orf54,NEK11,PEX26,SLC12A4,SLC22A4,UNC5B,ASTN2,LMF1,ZNF24" Drug 3712_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "C1QTNF1,ADGRF5,ALK,APC,GAS7,SLC4A4,ALDH7A1,ADGRB2,SCAPER,IL33,CBFA2T2,SH2B1,ABCG1,DAPK3,SPOCK3,CDON,DUSP9,ING4,ETV1,CORO2B,SEMA4D,GNG4,BACH2,SHISAL1,ADAM22,NFYA,MINDY2,CEP41,GSTCD,CSRNP3,ZNF821,FAM214B,WSCD1,DNAH7,TPM2,VIPR2,WNT7A,REEP1,UPF3A" Drug 4186_DN Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "APC,ARRB2,RAB28,IQCK,RGS6,SNPH,BRINP1,MTSS1L,SEMA4D,FYB1,PRRC2B,LPAR4,GRM8,SOX21,SHISAL1,LMO2,MAPT,NOVA1,ENPP2,RETREG1,POLG,PTPRB,RGS4,SBF1,FRMPD1,KANSL3,MYH15,IQCE,TNS2,TIAM1,TIMP4,UBTF,UGT8,VGF,VIPR2,NDRG4,EVI5,KCNAB1,TIGD6" Drug 3139_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "RALGAPA1,BIN1,APBB2,APOC1,MTMR3,ARHGEF1,CNTN1,PDE4DIP,RUBCN,SPOCK2,DBT,MRNIP,VPS13B,ETV1,PTK2B,ATP2C1,GAA,ADAM28,MUM1,TJAP1,IL6ST,LAMA2,MAP4,NRCAM,OXTR,PFKFB4,PIK3R1,PLCD1,PLCL1,CNNM2,CNTLN,SH3BP2,SLC6A8,DNMBP,KAT6B,TNS1,TRPS1,LMF1,AAAS" Drug 4280_DN Tropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "APOC1,SYNJ2,CAST,SPAG9,CHN2,AKAP7,ENTPD4,ARHGAP24,DTNA,FCF1,SEMA4D,FLT1,CINP,PRELID3A,INPP5K,SPIN1,TDRKH,RASSF8,IL6ST,TAGLN3,CLDN11,RETREG1,STRN3,MAPK7,GRAMD1C,ACSS3,SLC25A36,CCDC88A,SNCA,KDM4C,SYT1,ASTN2,DICER1,GPR161,THRA,TFIP11,EVI5,SEMA3B,KAT6A" Drug 3479_DN Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "NDRG2,ADRA1D,ALCAM,APBB2,APC,ARHGEF7,CAMK2G,PLEKHB1,IQCK,SOCS5,DBN1,EDNRA,EIF4G2,MRNIP,ANKFY1,SYT17,GCNT2,GLYR1,LPAR4,CACFD1,LSS,MAPT,MIA2,SETD4,OXTR,PDPK1,RETREG2,DCUN1D2,NEK11,KDM4B,SOX3,FNBP1,CAMTA2,THSD1,PLCB1,CDK20,ZKSCAN5,LMF1,AAAS" Drug 6625_DN Hydrochlorothiazide [58-93-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "NME5,ST3GAL5,AKAP7,SLITRK5,EXOG,CDON,ZNF549,FKTN,FGFR1,PDLIM5,ERAP1,SEPT9,GCNT2,SESN1,ZNF276,GPD2,STON1,SPACA9,DHX35,TJAP1,LIG4,LYRM9,CNOT4,MAPK7,SH3TC2,ZCWPW1,KIRREL1,ZNF821,AMBRA1,FNDC3A,ZBTB43,DDN,THSD1,SS18,SEPT8,ASTN2,FBXW11,RPGRIP1L,WIPF1" Drug 6209_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "ASPHD1,PKP4,APLP1,CDC14B,USP2,CBFA2T2,PLAA,QKI,CREM,GIT2,DNM1,DTNA,APH1A,ZNF589,FER,ATP2C1,PRELID3A,MALT1,COPS8,GNG4,GRB10,DHX35,IL6ST,ITPKB,MAP4,SH3BP2,BTBD7,ZBTB43,PHLDB1,VPS13A,TACC1,CHST8,AP4E1,ZNF34,HIRA,BCL2L13,VIPR2,SEMA3B,MPPE1" Drug 1647_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "SPARCL1,AMH,BIN1,CDC42BPA,HIP1R,LRRFIP1,LHX2,HOMER3,PICK1,CSNK1E,OSBPL3,RIMS2,ERAP1,SYT17,MALT1,GRB10,L1CAM,MAP4,CDK18,ENPP2,RETREG1,PRKAR1B,PTCH1,KHDRBS2,SH3BP2,PEX26,ARFGAP1,MAPKBP1,SOX3,SPTAN1,IQSEC2,DIP2A,STX1A,TBL1X,WSCD1,TRIM2,WBP2,UBTF,VGF" Drug 7315_UP Isotretinoin [4759-48-2]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "SPARCL1,APC,EPB41L5,GAS7,APOC1,CDK10,CDK13,ALDH7A1,ATP6V0A1,RUNX1T1,EPS15L1,SULT4A1,AKAP7,CREM,RUSC2,DLC1,IQCG,ZNF44,GAD1,SRCAP,GNAO1,SPACA9,NDP,NEFH,PALM,PDE4D,ABCB1,MAPK3,WDR25,RGS4,NLGN1,SLC11A1,SNCA,DOK5,ZHX3,ARHGAP26,RPGRIP1L,TIAM1,XRCC4" Drug 6162_DN Mesalamine [89-57-6]; Down 200; 26.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "ABHD6,BRAP,MTUS1,PKP4,CAPN3,SOCS6,PPP1R16B,DOCK4,DBT,RUSC2,DTNA,FHL1,FYB1,ERAP1,SEPT9,MAP4,NEK1,NFYA,SLC11A2,OGG1,OPA1,MAPK3,SAMD9,TMEM260,SBF1,AMBRA1,BTBD7,COA1,ZHX3,TROVE2,ARHGEF9,DNMBP,TBL1X,PARD3,TNS1,FLRT2,LAT2,ZNF24,KAT6A" Drug 6189_UP thioridazine hydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 39 193 "AP2A2,FGD2,APBB2,PLA2G4C,SLC4A4,ATP6V0A1,BMP7,CFAP410,CA12,CHN2,CHRNA4,CSF1,PDE4DIP,MBNL2,MRNIP,BAIAP2,IQCG,PCLO,KHK,LAMA2,LSS,MYO7A,OPRL1,PCDHGC3,CCSER2,RETREG1,CEP41,GAL3ST4,NEK11,PPM1E,SLC11A1,SPP1,NFASC,TPM2,HIRA,LMF1,SLC30A3,PRDM10,ADAMTSL3" Drug 6064_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.43E-04 1.00E+00 2.78E-03 3.13E-02 37 180 "NME5,APLP1,MARK4,ST3GAL5,CLGN,WHRN,AKAP12,PDE4DIP,ARMCX2,RASGRP2,FYN,CYP46A1,RAB40B,STON1,KCNB1,MXI1,NEK1,TMOD2,SERPINI1,GRAMD1C,PRPH,PTCH1,RPS6KA2,SH3GL3,ASAP3,WDR47,SMARCD3,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,BEX4,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug 6838_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "CDC42BPA,CDK13,SYNJ1,CACNA1A,CACNA2D1,ARHGAP33,CNOT8,SLIT2,TPP1,FAM149A,WHRN,RGS6,RIPOR2,SPOCK2,TMCC2,MBNL2,PLXNC1,HSD17B14,VPS13B,IGSF6,REEP2,DLC1,AFF2,GAD1,SEPT9,GPER1,PCLO,HNMT,ADAM22,MSR1,ZNF862,CCDC40,RGS12,ASAP3,SLC14A1,CEP68,WSCD1,TNS1,VIPR2,SPHK2" Drug 2652_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "AP2A2,EPB41L5,PPFIA3,CDC14B,MARCH3,NCOA1,CFLAR,PLEKHB1,SOCS5,SUGP2,IRAK4,AGAP2,CSPG5,SYT17,MALT1,POLL,GPER1,HNMT,MAP4,MAPT,MMP16,SLC11A2,PDE4A,ELOVL2,PTPRG,RGS3,ZNF821,FBXO11,MAPKBP1,SNCA,CDK19,ZBTB43,TROVE2,PHLDB1,EXOC7,TIAM1,VGF,XRCC4,PCBP4,MPPE1" Drug 3528_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "NDRG2,FAM131A,ARSE,DNAH17,NRP2,CFAP410,SEPT7,CACNA2D2,PLEKHB1,NDST3,AKAP7,ENTPD4,CLIP3,CSF1R,OSBPL3,RASSF2,DBT,CDON,HIPK3,RASGRP2,ZNF589,TPK1,TPPP3,FYB1,GALC,SEPT9,ALDH1L1,GNG4,GPD2,GPER1,ITGA7,ADAM22,NTRK2,NECAB2,MAPK7,PSD,ZFHX4,TCP11L1,WSCD1,VGF" Drug 3068_UP Meglumine [6284-40-8]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADD2,ADORA1,CASK,ARRB1,THSD7A,ENTPD6,KCNAB3,CHN2,CHRNA4,STOML1,ABCG1,RIPOR2,CDON,E2F5,VPS13B,LRRC17,RASGRP2,FHL1,GAD1,ALDH1L1,GCNT2,ADAMTS13,HNMT,KCNJ5,MAP4,MGAT3,TAGLN3,MYO6,CCSER2,PRKAR1B,TMEM255A,RGS12,STUM,FUZ,EPN2,TSNAXIP1,SPTAN1,SEPT8,CHST8,VGF" Drug 6071_DN Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "AP2A2,SEMA6A,DOC2A,BCAS1,CA4,HAP1,ARHGEF2,PICK1,SLC4A8,RCHY1,SIPA1L1,CNTNAP2,FAM169A,DZIP3,DBN1,DUSP9,ING4,COQ7,NCALD,ZNF589,FGFR1,IQCG,TDRKH,RASSF8,INPP5B,TM6SF1,MPP2,NF1,PRKAR1B,MAPK7,GRAMD1C,PRODH,NKAIN1,PREX2,SLC6A8,COA1,VPS13A,EXOC7,VGF,VIPR2" Drug 3385_DN Nizatidine [76963-41-2]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "AP2A2,LTBP4,APBA2,PDE8B,CFLAR,SYNJ1,GYG2,CACNA2D2,ABI3BP,JAKMIP2,PARD6A,EDNRA,OPTN,PLXNC1,EIF4G2,DLC1,SPACA9,ATXN2L,ELOVL5,IL6R,KHK,MAPT,PALM,PDE4A,NLE1,PTPRO,C1orf54,EMID1,RASA3,CPEB3,PREX2,SLC9A5,SNCA,THSD1,TBCEL,SMG6,CDK20,ZKSCAN5,UCHL1,KAT6A" Drug 6477_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "BEGAIN,APOC1,ARHGDIG,CFLAR,KSR1,SYNJ1,SCAPER,CAMK2B,CDH2,TAOK2,HOMER3,AKAP7,DMPK,ING4,OLFM1,FGFR1,PDLIM5,TMEM8B,SIGLEC8,SMAD1,PALM,LRP12,PRKAR1B,ZMAT4,RGS12,RTN1,PPP4R3A,FAM214B,LIMCH1,ARHGAP26,CLSTN2,TACR1,WSCD1,TRIM2,TLR4,FAM155A,SLC30A3,SLC17A7,ADAMTSL3,JPH3" Drug 1519_DN Edrophonium chloride [116-38-1]; Down 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "OSBPL1A,FAM131A,PPFIA3,CAMK2G,CCNT1,SLIT2,SULT4A1,CREM,SIPA1L1,PDE4DIP,KIAA0586,TMCC2,DTNA,HIPK3,CNNM1,MPP6,ARFIP1,GLYR1,RAB30,GRB10,DIDO1,HSF2,INPP5B,IPO5,MAP4,NFYA,FSD1,TRAPPC13,ZNF821,SH3BP2,FAM102A,FUZ,FAM214B,PLCB1,ARC,CRTC1,ZNF24,SPHK2,GDPD5,ST7" Drug 4213_DN Austricine [10180-88-8]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADCY6,BRAP,APOC1,ARHGDIG,DNAH17,RIPK1,IQCK,AATK,ARHGEF10,ARHGEF4,SPOCK3,DUSP9,EGFR,PLXNC1,CDKL3,F5,ZNF589,FGFR1,CINP,OGA,DISC1,GPD2,GRM8,KCNF1,KHK,KPNA5,PACRG,OGG1,ENPP2,PTPRN2,ZSCAN2,ZCWPW1,GSTCD,CRTC1,TIAM1,TIMP4,RIMBP2,REEP1,ZNF225,MPPE1" Drug 1914_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "GAS7,EIF4G3,PTBP2,SRSF11,APPL1,ZFYVE16,ZNF337,SEZ6L2,VPS26C,ATP2C1,STAU2,ERAP1,INPP5K,DBF4,GLYR1,MAP4K5,HNMT,NEK1,SETD4,PIK3C2A,CCSER2,PPM1B,CEP97,GTDC1,CCDC25,SH3GL3,SHMT2,ABLIM3,SLC11A1,KBTBD4,ELMO2,RCOR3,PEG10,POGZ,ZEB1,NSD1,CBX5,EIF4ENIF1,UBE3A,DPF3" Drug 1478_UP Prednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADORA2A,AP2A2,SPARCL1,BEGAIN,AMPD3,BIN1,CDC42BPA,APOC1,ADAM15,ST3GAL5,SCAPER,P2RX6,PICK1,RIMS2,BRINP1,MBNL2,ERBB4,DLC1,ZNF589,FGF1,BAIAP2,FHL1,B4GALNT1,GPD2,KCNQ3,MSI1,CDK18,SLC25A23,PRKAR1B,TMEM104,PTPRD,PTPRO,NUDT11,SLC9A5,KIF13A,SSTR2,TACC1,MCF2L,CHST8,UCHL1" Drug 5497_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "NDRG2,FZD9,BIN1,FAM131A,ARHGDIG,ARSE,CFLAR,GYG2,CACNA1G,ARHGEF1,RCBTB2,AKAP6,CPS1,RIMS2,TBC1D5,MAML1,DBN1,LYPD1,GSDME,BAIAP2,FHL1,PDLIM5,CNTRL,JAK2,LIG4,MAN2A2,MSR1,LRP12,PRKCB,SNRK,PTPRO,CRTAC1,ZNF821,SLC2A5,COA1,DOK5,LMO3,TPM2,RUNDC3B,PHTF2" Drug 2165_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ABHD6,DOC2A,APC,ADAM23,SYNJ2,CACNA1A,HIP1R,PLAA,TMEM184B,SLITRK5,SPATA2,DTNB,CELSR3,RASGRP2,CDKL3,PDLIM5,SEPT9,GLYR1,POLL,GNG4,STON1,DIDO1,GIT1,MX1,TREM2,PLCD1,PLTP,PMP22,POU6F1,PTPRN2,SEC14L1,ZNF821,GALNT10,ANKRD6,UNC5B,TROVE2,PLCB1,ZBTB38,UBE3B,PHTF2" Drug 5270_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "SPARCL1,KSR1,CACNA1I,CDO1,CNTN1,GREB1,EGR3,ERCC2,GATM,SRCAP,ADAMTS13,GSN,TJAP1,KCNF1,MAPT,MBD1,MMP17,MSI1,ADAM22,MX1,PCBP3,SERPINI1,PLTP,CEP41,ENOX1,RGS12,ASAP3,NMNAT2,ARHGAP26,DMXL2,PCDHGB6,R3HDM1,CHST5,TRPM2,WIPF1,SEMA3B,SLC17A7,KCNAB1,ITM2C,PLSCR4" Drug 3354_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "NDRG2,APOC1,CDK13,N4BP2L1,CFAP410,USP2,STOML1,AKAP6,WHRN,TMCC2,EXOG,EDIL3,ERCC2,FHL1,PDLIM5,DLL3,RUNDC3A,KCNN2,MAPT,NF1,NNAT,C1orf54,RGS4,ZFHX4,RASA3,ASAP3,PKNOX2,CLSTN2,JMJD6,SYN2,SLC35G2,GPR161,TLR4,HIRA,WIPF1,LAT2,KCNK12,SPHK2,EMSY,PLSCR4" Drug 4701_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADRA1D,BIN1,APBA2,APBB2,MARK4,NCOA1,KYAT1,FOXN3,B4GALT6,AKAP7,BAG4,SH2B1,CSF1R,ARHGEF4,MFAP3L,DTNA,ST3GAL6,FHL1,CGREF1,FYN,TRAF3IP2,ERAP1,INPP5K,GFER,MSL3,GNG4,TDRKH,HNMT,KPNA5,PDPK1,PRKAB2,CNNM2,ARHGAP26,RPGRIP1L,PARD3,TPM1,VIPR2,XRCC4,KAT6A,TIGD6" Drug 6086_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADORA1,AGT,C1QTNF1,SEMA6A,LTBP4,CDC14B,PLA2G4C,CAMK2B,COL9A3,MYRIP,CSF1,GREB1,ERBB4,PTK2B,DCTN2,ERAP1,SIGLEC8,DISC1,AP4S1,IFI16,KIFC3,TAGLN3,NF1,RETREG1,MTRF1L,LRP12,PPP5C,TRIM68,RGS12,NUDT11,TCP11L1,ST6GAL1,ARHGEF40,SLC11A1,SPTAN1,SYT5,TRIO,SLC17A7,ITM2C,JPH3" Drug 5772_DN Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "PPFIA3,RIPK1,QKI,VCAN,DBT,RUSC2,C2CD2L,TOM1,EDNRA,MBNL2,HSD17B14,ERCC2,CDKL3,FECH,FGF13,FGFR1,TRMO,PCDH17,KCNMB4,GPR37,BACH2,TJAP1,NPR2,SLC11A2,PFKFB2,SERPINI1,PTPRH,FAT4,BEND5,SUGCT,ZNF821,SUPT20H,FAM102A,TROVE2,PHLDB1,TNS1,NDRG4,NAV3,KCNAB1,GAN" Drug 3758_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "SYT13,ATP2B2,SLC2A11,GYG2,CAMK2B,KYAT1,CBFA2T2,FAM149A,WHRN,ERC2,PYGO1,HS3ST2,CALCRL,KAT8,OLFM1,FGF12,ALDH1L1,RUNDC3A,GNAO1,GPER1,ADAMTS13,GRIK5,MATK,MEF2C,KITLG,PCDH9,ENPP2,C19orf57,POU6F1,MASP1,PTPRO,SEMA6D,FRMPD1,SLA,PKNOX2,ARHGEF40,HECW1,TRIO,FLRT2,JPH3" Drug 3997_DN Cefotetan [69712-56-7]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "APC,DNAH17,NRP2,SH2B1,CRMP1,PARD6A,EIF5,ST3GAL6,AFF2,GFER,GPER1,GUCY1B1,KIF2A,MAP4,CNOT4,NOVA1,PDE1C,PDE4D,PLCD1,PTPRB,FAM184A,ZCWPW1,ENOX1,KIRREL1,FBXW7,FRMPD1,FNDC3A,EPN2,ARHGAP26,ZBTB43,ADGRL3,TK2,RPRM,OSBP2,PLPPR2,WIPF1,XRCC4,MAP3K12,KCNAB1,TIGD6" Drug 3425_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "APBB2,APC,APOC1,LGR5,ARHGDIG,ARRB2,MARK4,CNTFR,AKAP7,CPS1,HDAC4,DAPK3,DBN1,DTNA,EGFR,PLXNC1,ING4,ENO2,FAM198B,NSG1,GCNT2,RAB30,GNG4,TDRKH,GSN,KITLG,MMP16,ADAM22,NTRK2,SLC25A23,PTPRE,TCP11L1,CCDC88A,SNCA,SPART,PHLDB1,SYNE1,ZNF34,TK2,REEP1" Drug 6617_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ANK2,KCNAB2,BCAS1,N4BP2L1,ATP6V0A1,ADGRB1,BMP7,CAMK2B,CNTFR,DGKB,DTNA,EDNRA,HIPK3,AGAP2,ERAP1,TMEM8B,KIT,LIFR,MMP16,ADAM22,NEFM,NOVA1,PFKFB4,PPARA,PPP5C,ZSCAN2,TCP11L1,ASAP3,SLC2A5,PEX26,HECW1,PHLDB1,COBL,TACR1,TNS1,SMUG1,TRIO,ZNF24,KCNAB1,EPM2A" Drug 2997_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ABHD6,C1QTNF1,DOC2A,AMPH,BIN1,APAF1,APOC1,ATP1A3,MYOM1,CHN2,PCYT1B,DGKG,HIPK3,TNK2,F5,FGFR1,GAD1,NEU3,ALDH1L1,STMN2,KIT,MYCN,NDP,PFKFB2,CCSER2,PURG,STRN3,PPP2R2B,PTPN13,GAL3ST4,RGS12,PKNOX2,SLC12A4,TSNAXIP1,SYN2,SYT1,PCDHGA10,CRTC1,ZKSCAN5,FLRT2" Drug 4598_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ACTN1,ALK,SCAPER,BAIAP3,CACNA1A,MAGI1,RAB28,HOMER3,AKAP5,SH2B1,CSF1R,CNTNAP2,MFAP3L,CSPG5,DISC1,MSL3,POLL,GNAL,HLF,KCNN1,KIFC3,MN1,LYRM9,NF1,PDE4B,SAMD9,FAM184A,KHDRBS2,GAL3ST4,RGS4,RNASEL,GSTCD,TCP11L1,CCDC88A,ZNF415,SYN2,MCF2L,RPGRIP1L,TRIO,PCBP4" Drug 5744_UP Calycanthine [595-05-1]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ASPHD1,AMH,APC,BCAS1,CDK10,SYNJ1,BAIAP3,CFAP410,HAP1,CBS,HOMER3,PICK1,WHRN,CNTNAP2,PHF14,SPOCK2,MYEF2,EDN1,RCAN2,APC2,CDKL3,ZNF44,DENND2A,ALDH1L1,STON1,TAGLN3,PDE4D,CNNM2,GDPD2,PTN,RFX2,FBXW7,STUM,ASAP3,ZNF334,SOX15,ELOVL4,ARC,SLC44A1,AMACR" Drug 2272_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "SYN3,AK2,APC,RHBDL1,CDO1,WHRN,CPS1,CNTNAP2,RIMS2,HDAC9,SPOCK2,MBNL2,IGSF6,FGFR1,GAD1,PRUNE2,PRDM5,RASSF8,ITGAM,KCNJ5,KCNN1,MEF2C,ADAM22,PFKFB2,ZFHX4,ASAP3,SLC2A5,PKNOX2,CXXC4,HECW1,ARHGAP26,CDK19,ATP10B,JMJD6,ARC,WSCD1,HIF3A,NT5M,SLC17A7,KCNAB1" Drug 6612_DN Palmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "NME5,APC,KIF1A,CACNA1A,RAB28,HOMER3,IQCK,WHRN,HINFP,NCOR2,CDON,STX2,TRMO,CINP,DENND2A,GAD1,INPP5K,CRCP,POLL,IL6ST,MAP4,MAPT,SCAMP5,AFDN,ZNF862,NF1,STRN3,SAMD9,RPS6KA2,ASAP3,ZNF415,SYT1,SYNE1,THRA,TIAM1,CABIN1,METTL3,TRIO,TFIP11,VPS35L" Drug 3619_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADORA1,SEMA6A,CACNA1I,CFAP410,CAMK2G,HIP1R,USP2,CDH2,CSF1,DOCK4,RUSC2,SPOCK3,RASGRP2,ERCC2,AFF2,FUT9,SRCAP,LILRA2,SYNPO,JAK2,KCNH2,KCNJ5,KCNN1,KHK,MAPT,NPY,PFKFB2,NUDT11,EMID1,ASAP3,DZIP1,SLA,HECW1,ZBTB43,ARC,SYN2,GPR161,LAT2,MPPE1,DPF3" Drug 6472_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "CDC42BPA,APBB2,CAMK2A,DLGAP1,CHRNA4,TAOK2,CNN3,CNR1,WHRN,COL9A3,CTH,RIMS2,BRINP1,RUSC2,DTNB,DLC1,AGAP2,GALC,SIGLEC8,NEU3,SPACA9,HLF,KIT,PACRG,MMP16,OPRL1,SLC25A23,PPP1R1A,ELOVL2,CCDC40,SEMA6D,SLA,SLC2A5,PPP4R3A,SNAP25,SPP1,SYT5,HIF3A,VIPR2,WIPF1" Drug 6023_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "SYN3,AMPH,BIN1,APOC1,SLC4A4,FUBP1,GYG2,CACNA1I,LDLRAD4,CDH2,CBARP,TAOK2,SH2B1,AATK,VCAN,PDE4DIP,GREB1,SPOCK2,HSD17B14,STX2,HPCAL4,KHDRBS3,FYN,GCNT2,HPGDS,GNAO1,NXPH3,TJAP1,ADAM22,TAGLN3,NTRK2,PLCL1,EMID1,ZFP2,HKDC1,PKNOX2,SLC9A5,ZNF415,TBCEL,SPHK2" Drug 2719_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "KDM5D,ADORA1,BEGAIN,LGR5,ZSCAN18,MYRF,CDO1,CHN2,SPOCK2,DBT,DMPK,EDIL3,ANKMY1,ARMCX1,DLC1,FLT1,PRELID3A,NSG1,RUNDC3A,ICA1,FAM69A,MGAT3,MMP17,NEFM,CLDN11,OXTR,TMOD2,PLCD1,PNMA3,FSD1,BCAS3,PTPN13,PBRM1,FAM214B,TACR1,TCF4,CHST8,ZKSCAN5,UBE3A,ZBTB38" Drug 6005_DN Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "AP2A2,TRMT9B,APC,ARHGDIG,PDE8B,NCOA1,ARHGEF7,CREM,PDE4DIP,FAM169A,GREB1,DCAF8,DBT,ZNF804A,EDNRA,STX2,ACSL4,BAIAP2,GAD1,USP19,GLYR1,CNTRL,HNMT,IL6ST,IPO5,ZNF862,NF1,LRP12,PTN,RNASEL,MRAS,ZHX3,SPART,IQCE,CHST8,VIPR2,ZNF711,GDPD5,HPS4,KCNAB1" Drug 4588_UP Vitexin [3681-93-4]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ADD2,AGT,LTBP4,BEGAIN,APOC1,PPP4R4,PTCH2,CACNA1I,CREM,CRY2,CSF1,VCAN,PDE4DIP,PLPPR4,SPOCK3,DMPK,DTNA,PLXNC1,TENM1,EPHB1,ZNF549,ETV1,REEP2,ST3GAL6,NSG1,ERAP1,FAM69A,KCNB1,NF1,P2RX7,PPARA,PTPRB,CCDC40,ST6GAL1,TSNAXIP1,SOX15,HECW1,FBXW11,TRIM2,ZNF711" Drug 1681_DN Epirizole [18694-40-1]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "BRAP,PKP4,CASK,ATP2A2,ATP6V0A1,SYNJ2,PTBP2,COL4A5,CREM,LRIG1,RUBCN,DBN1,PARD6A,FEM1B,SUGP2,DENND4A,KAT8,FGFR1,TRMO,CSPG5,FERMT2,SLC2A6,MPP2,RIPOR1,TMEM231,ZCWPW1,FBXW7,ZC3H14,ZSWIM8,KDM4C,CAMTA2,ITPRID2,TBL1X,CLASP1,WBP2,METTL3,HIRA,ZNF184,SEMA3B,RNF170" Drug 4080_UP Cefadroxil [50370-12-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "ATP2B2,BMP7,CACNA1I,RHBDL1,CBFA2T2,KCNAB3,MAGI1,NRXN3,STOML1,FAM189A2,HAPLN1,LRIG1,CYBB,SPOCK2,DTNA,FRY,ING4,TNK2,AGAP2,GRIK4,HLF,IL12A,NEFH,NRCAM,MAPK10,ACSS3,RGS4,KLHL11,KCNIP1,RTN1,ZFP2,RASA3,SNCA,ZHX3,MCF2L2,PHLDB1,OBSL1,TLR4,FLRT2,DPF3" Drug 3131_UP Scopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.89E-03 3.26E-02 40 200 "SYN3,SPARCL1,ALK,TRMT9B,AMPH,APBB2,PPP4R4,CACNA1I,KALRN,LARGE1,SULT4A1,CNN3,PICK1,CREM,AATK,PDE4DIP,ARMCX2,MTSS1L,FGFR1,HPCAL4,DCTN2,ALDH1L1,PRUNE2,ICA1,SCIN,KCNN1,MAP4,ADAM22,NPY,NTRK2,PFKFB2,PPP2R2B,RELN,ENOX1,NEK11,LHPP,CRTC1,FLRT2,LMF1,TFIP11" Drug 6177_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.56E-04 1.00E+00 2.90E-03 3.27E-02 36 174 "CLK4,CAMK2G,KRIT1,CD38,TPP1,CREM,PDE4DIP,DGKG,HS3ST2,FAM13A,MBNL2,MRNIP,VPS13B,FGFR1,BAIAP2,AGAP2,ATP2C1,STON1,MUM1,NRCAM,NTRK2,PDE4B,PDE4D,MBOAT7,PPM1B,PRKACB,MAPK7,HSPA4L,KDM4B,SPATA7,ARHGAP26,SPTAN1,TPM1,FLRT2,ZBTB38,FXR1" Drug 1019_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.56E-04 1.00E+00 2.90E-03 3.27E-02 36 174 "LTBP4,OGT,APBB2,BACH1,SYNJ2,PDE4DIP,INTS1,DBT,DNM1,ING4,EZH1,ZNF589,ERAP1,INPP5K,BRD8,STON1,GRIK5,HNMT,LMO2,MXI1,LYRM9,ZNF862,MINDY2,CNNM2,PTCH1,ASAP3,SLC9A5,BTBD7,KDM3A,CDK19,CEP68,SZT2,NR2C2,RUNDC3B,MARCH8,UBE3B" Drug 7368_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.57E-04 1.00E+00 2.91E-03 3.28E-02 38 187 "EPB41L5,SEMA4G,MADD,PDE8B,C5,PLAA,PCYT1B,WHRN,CNTNAP2,CTH,EXOG,EIF5,FOXF2,OGA,ALDH1L1,GCNT2,GPER1,GRM8,SHISAL1,TJAP1,KIT,TAGLN3,NDP,NF1,CLDN11,KCTD15,SMOX,PPARA,PRKAR1B,CNNM2,FBXW7,SPTAN1,PHLDB1,CRTC1,TK2,R3HDM1,TNS1,WIPF1" Drug 3283_DN Digoxin [20830-75-5]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.57E-04 1.00E+00 2.91E-03 3.28E-02 38 187 "APAF1,CFLAR,TAOK2,CLCN3,ARMC8,SMARCAL1,DZIP3,ZNF337,GIT2,ZBTB24,RHOBTB1,ANKRD46,EGR3,EIF5,ARMCX1,JAK2,PDCD2,PIK3R1,NLE1,ZSCAN32,PTPRE,TMEM231,RAD51D,ROBO1,ZC3H14,MAP6D1,TRAPPC13,ZFP30,ZNF302,CEP68,ZC3H4,ARHGEF9,ANKRD12,TBL1X,TRIM2,ZNF23,ZNF32,ZNF184" Drug 3278_DN Naringenine [480-41-1]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.57E-04 1.00E+00 2.91E-03 3.28E-02 38 187 "AP2A2,ALK,GAS7,BCAS1,PPFIA3,MARK4,CFLAR,SYNJ2,GYG2,CA4,CSF1R,DTNA,FCF1,OPTN,IRAK4,FHL1,EFCAB2,OGA,ARFIP1,SPACA9,GSN,ATXN2L,TJAP1,KITLG,LYRM9,NFYA,PCDH9,PIK3R1,PRKAR1B,RGS12,KDM4C,POGZ,DIP2A,STX1A,TNS2,TRIO,REEP1,KCNAB1" Drug 953_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.57E-04 1.00E+00 2.91E-03 3.28E-02 38 187 "NDRG2,OSBPL1A,MPDZ,CFLAR,SCARB1,FOXN3,VAX2,ARMC8,AKAP5,CSNK1E,PDE4DIP,FAM169A,CTH,ARHGAP24,DBT,RCAN1,DTNA,DUSP9,FHL1,ATP2C1,B4GALNT1,GRB10,JAK2,KLK6,ZSCAN2,MORC4,TCP11L1,HSPA4L,SGK1,SH3BGR,ZFP30,FBXO11,PREX2,SLC2A5,TROVE2,FBXW11,VLDLR,FXR1" Drug CID000065863 sertaconazole Stitch 2.60E-04 1.00E+00 2.94E-03 3.31E-02 43 220 "SYN3,SPARCL1,ALCAM,APBA2,ARNTL,SYNJ1,CA4,GAD1,DISC1,MCHR1,FAM107A,AGFG1,KCNN3,MAPT,MBP,BLOC1S2,MXI1,PCDHGC3,PDE4B,SERPINI1,POLR2F,PPP2R2B,PPP3CC,PRODH,RELN,RAD17,ST6GAL1,SMARCA4,SNAP25,SNCA,RHBDL3,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA2,NPL,PDSS1,HIRA,POLR3H,SLC30A4,RTN4,HNRNPA3" Drug 1868_UP Dapsone [80-08-0]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "MTUS1,AMT,ARNTL,ADAM23,BMP7,SYNJ1,RUNX1T1,CBFA2T2,TAOK2,IQCK,CSF1,DAPK3,DBT,KIAA0753,HEYL,MRNIP,ZNF589,ANKFY1,AHDC1,GLYR1,LILRA2,ICA1,LIG4,MATK,GIT1,NEFH,CNOT4,MAPK7,SATB1,ZNF821,FAM102A,FUZ,ZNF667,TSNAXIP1,ZEB1,TNS1,LMF1,XRCC4,PHTF2" Drug 7442_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "LTBP4,APAF1,SEMA4G,SYNJ2,GYG2,ARHGEF6,RIMS2,PPP6R2,GIT2,DNM1,DTNA,TOM1,MBNL2,COQ7,ZNF589,BAIAP2,PRKAG2,FAM49B,SYT17,POLL,ELOVL5,AGBL5,INPP1,ZNF862,MYT1,SETD4,PTCH1,RNASEL,RPS6KA2,SH3BP2,EPN2,LIMS2,SLC22A4,PLCB1,EXOC7,KIAA0930,MAP3K12,MPPE1,PHTF2" Drug 7352_UP Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "LTBP4,ALK,DNAH17,KIF1A,SIPA1L1,PDE4DIP,DCAF8,GIT2,DMPK,STX2,FER,FHL1,PDLIM5,GALC,SRCAP,RAB30,POLL,GNAO1,GNG4,STON1,SPACA9,RASSF8,ATXN2L,IL6ST,MEIS2,LYRM9,NF1,LRP12,APTX,RIPOR1,SBF1,ABLIM3,SLC22A4,RBM34,TROVE2,KIAA0930,THRA,CABIN1,RUNDC3B" Drug 3556_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG2,ADORA2A,SPARCL1,APC,CFAP410,CA4,MTMR7,ARHGAP33,PLEKHB1,LY86,ARHGAP24,ARMCX2,KLHL3,LRRC17,IGSF6,KHDRBS3,GAD1,SPACA9,KHK,MSR1,MYO7A,NF1,PALM,GPR85,PPP2R2B,MAPK10,PTPRH,C1orf54,PNMA8A,FNDC3A,ST6GAL1,PEG10,ARHGAP26,TSPYL2,SYT5,TBCEL,TRIO,NT5M,AP3B2" Drug 1748_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG3,OSBPL1A,C1QTNF1,SPOP,CAMK2B,PLAA,HINFP,ARHGEF10,ZNF337,MED12,RASGRP2,SEMA4D,HTATSF1,MAN2A2,MAP4,MBD1,SCAMP5,AFF1,MYO9A,NEFH,NF1,OPA1,RETREG1,MRPS18A,DGLUCY,SLC11A1,TSPYL2,POGZ,ANKRD12,TCF4,TSN,HSPBP1,HIRA,VIPR2,LAT2,XRCC4,TRIM9,CIAPIN1,PDSS2" Drug 5696_DN Androsterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ASPHD1,ADCY6,BIN1,APOC1,ARRB1,CFLAR,MTMR2,CLGN,PLEKHB1,QKI,HOMER3,DCAF8,GIT2,DBT,JAKMIP2,LYPD1,DTNA,PHF20L1,FGFR1,BAIAP2,PRELID3A,GLYR1,RNFT2,HNMT,MAP4,MMP16,ZNF862,NFYA,SLC25A23,PPP2R2B,RXRA,FERMT1,SIRT2,ZHX3,SPTAN1,MCF2L,XRCC4,ZBTB14,SMIM8" Drug 6201_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADD2,APBB2,SEMA4G,ADAM23,SCAPER,CAMK2G,CAPN3,AP4M1,TAOK2,CPS1,CTH,TBC1D5,SPATA2,SGSM2,EIF1,PTK2B,FECH,ANKFY1,FAM49B,CAMKK2,FYN,GLYR1,CACFD1,CNOT4,OGG1,PDE4D,PPP5C,NCBP3,ST6GAL1,TSPYL2,ZKSCAN5,HIRA,PLPPR2,VLDLR,XRCC4,ATP6V0E2,ZNF225,KCNAB1,ACTR3B" Drug 6553_DN 5194442; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG3,AMT,STX16,ARHGEF1,NRXN3,RAB26,CPS1,DZIP3,PARD6A,EDIL3,EDNRA,FCF1,CNNM1,ZNF589,FER,PDLIM5,CSPG5,SYT17,ZNF276,COPS8,CNTRL,HNMT,IL6ST,MSR1,NF1,NFIX,CNOT4,PLEC,KIRREL1,MAPK12,FBXO11,KBTBD4,ZNF415,IZUMO4,FBXW11,WSCD1,TMPO,HIRA,RPRM" Drug 6165_DN "ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "AK2,APC,CDK13,STX16,CFLAR,LDLRAD4,CFAP410,CAMK2G,HINFP,DOCK4,RUSC2,SGSM2,TUBD1,COQ7,FAM49B,SRCAP,GSN,SLC2A6,ATXN2L,TJAP1,SLC11A2,PIK3R1,LRP12,MBOAT7,PRKAB2,SNRK,SEC14L1,FAM214B,TMCC1,ZHX3,ARHGAP26,ZBTB43,DDN,DIP2A,EXOC7,NSD1,HIRA,PLPPR2,ZBTB14" Drug 3404_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG2,BRAP,APBB2,APOC1,PPFIA3,ARHGDIG,PDE8B,PCYT1B,SNCAIP,HDAC4,SGSM2,TOM1,VPS13B,FHL1,SCARA3,GAD1,ALDH1L1,SPACA9,LMO2,KITLG,NTRK3,ZSCAN32,GSTCD,TCP11L1,PREX2,LIMCH1,RBM34,ZNF423,ZBTB43,SPART,CLSTN2,ST5,PHLDB1,MTCL1,VGF,ZFP37,REEP1,MPPE1,MARCH8" Drug 346_UP 2-propylpentanoic acid; Up 200; 2000uM; MCF7; HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NME5,ANK2,AQP6,NRP2,BMP7,GYG2,RAB29,SYNGR3,RASSF2,JAKMIP2,TMCC2,TNK2,EXTL2,ARMCX1,ZNF589,FGFR1,FYN,SYT17,RUNDC3A,RAB40B,GRB10,ADAMTS6,KCNH2,MMP16,MBOAT7,SH3GL3,ASAP3,ST6GAL1,SYBU,KBTBD4,ELOVL4,AGTPBP1,TRIM2,TMEM121,BEX4,TST,REEP1,MPPE1,IFT88" Drug 3861_DN Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "DOC2A,CDC42BPA,APBB2,APC,DNAH17,MARK4,BAIAP3,CBFA2T2,ARHGAP33,TAOK2,AKAP7,ZNF804A,DNM1,ING4,ELN,FGF12,FGFR1,EFCAB2,PDLIM5,B4GALNT1,SRCAP,GFER,ATXN2L,ITPKB,ZNF862,PDE4A,PFKFB2,PLEC,SNRK,ZDHHC14,SH3BP2,SNCA,TROVE2,TNS2,LAT2,ZNF74,NDRG4,MAP3K12,HPS4" Drug 2469_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG2,ADAM23,ADAM15,SYNJ2,CACNA1A,CLCN3,TPP1,RCHY1,CREM,CRY2,VCAN,TBC1D5,CNNM1,TUBD1,NCALD,F5,GALC,INPP5K,HTATSF1,POLL,TJAP1,KIF2A,MEF2C,SCAMP5,ZNF862,NF1,NFYA,CNOT4,PTCH1,PTN,TCP11L1,RXRA,MRAS,RASA3,ELMO2,TRPS1,LAT2,NLRP3,SENP7" Drug 4599_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "APC,C5,CACNA2D1,KRIT1,CREM,DZIP3,PHF14,DBT,DTNA,ING4,RRAGB,CORO2B,TRMO,MSL3,GPD2,CNTRL,ITGA7,JAK2,LIG4,MBNL1,PALM,PDE4D,PFKFB2,RETREG1,MINDY2,ZSCAN32,PTPRB,CCDC40,FBXW7,MCMBP,FBXO11,OGDHL,SNAP25,CDK19,TROVE2,TCF4,TMPO,CHST5,ZNF225" Drug 4506_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "APAF1,CFLAR,BMPR1B,FUBP1,CD86,CRLF1,PLEKHB1,TAOK2,ARHGAP22,LHX2,STOML1,SEC14L5,EXOG,DUSP9,ELN,PDLIM5,FYB1,GSN,PADI2,SMAD1,PDE4B,CEP41,ELOVL2,ZSCAN2,KCTD17,KANSL3,SLC11A1,KIF13A,RBM34,TSNAXIP1,TACR1,DMXL2,PCDHA6,AP4E1,SPHK2,REEP1,KCNAB1,EPM2A,GAN" Drug 582_DN butein; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ABR,APBB2,ADGRB2,CNTN1,PREPL,HAPLN1,AATK,MAMLD1,EGFR,RGS17,ERCC2,TAOK3,SEC23B,FYN,GALC,NEU3,PRRC2B,GPR37,KCNJ5,MBP,MMP16,NNAT,CCSER2,TRHDE,C19orf57,PTX3,CLIP1,KLHL7,PLCB1,PCDHA5,GPR161,TMPO,RPRM,CLDND1,ZNF23,EVI5,SLC17A7,KCNAB1,MPPE1" Drug 1278_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "APAF1,CASK,STX16,CNOT8,SLITRK5,ZFYVE16,DBT,SGSM2,RCAN1,DTNA,HIPK3,FRY,ZNF589,FHL1,ANKFY1,OGA,ARFIP1,LILRA2,TJAP1,KCNJ5,LSS,MEST,NFYA,SLC11A2,PURG,STRN3,RASA3,HSPA4L,PPM1E,FNDC3A,SLC2A5,PPP4R3A,TROVE2,NXT2,NSFL1C,ANKRD12,FBXW11,TK2,ACTR3B" Drug 4682_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NME5,TRMT9B,APBB2,ATP1A3,ADAM23,FUBP1,MTMR3,RAB28,NRXN3,ABCG2,RAB26,ARHGEF10,MFAP3L,CHRDL1,EDNRA,COQ7,CGREF1,LPAR4,GPER1,RASSF8,LIG4,MAPT,NDP,SLC11A2,PIK3R1,RETREG1,STRN3,GSTCD,CSRNP3,SOX15,IZUMO4,ASTN2,GPR161,TIAM1,TK2,ZKSCAN5,WIPF1,LAT2,FAM13C" Drug 3363_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADD2,ADORA2A,NME5,TRMT9B,ATP2A2,CA4,CAST,ARHGEF2,RAB33A,TPP1,NCOR2,AATK,ERBB2,F5,FHL1,FOLR2,GAD1,PRUNE2,GRB10,KIFC3,MID1,ZNF862,NELL2,NNAT,NOVA2,NPTX2,NTRK2,PCDHGC3,PLXNB1,KCNIP1,SALL1,LMO3,ZEB1,SZT2,TEK,TNS1,ADAMTS9,ITM2C,EPM2A" Drug 1827_UP Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ASIC1,LTBP4,CASK,ARRB2,MPDZ,HIP1R,CLGN,CHN2,CNOT8,PDE4DIP,DCAF8,DBT,FAM13A,APH1A,USPL1,EPB41L2,ZNF589,USP21,TPK1,DLL3,ARFIP1,STON1,MBNL1,MX1,CNOT4,PRPH,CNNM2,RBBP6,RPS6KA2,NCBP3,LMBRD1,CEP68,JMJD6,KIAA0930,TIAM1,METTL3,TST,HIRA,EMSY" Drug 4178_DN Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "AP2A2,AMT,ATP2A2,CACNA1I,ASIC3,SLIT2,CRY2,DCAF4,DUSP9,ING4,ELN,LRRC17,NCALD,DLC1,KHDRBS3,ERAP1,SEPT9,ALDH1L1,ADAMTS13,CACFD1,KCNN1,KCNQ3,ADAM22,NF1,PRKCB,SBF1,NLGN1,FAM214B,ZHX3,TROVE2,PLCB1,EXOC7,AP4E1,PARD3,CDK20,TPM2,TRO,WIPF1,PLSCR4" Drug 2391_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "MTUS1,PPFIA3,PRX,ARRB2,RUNX1T1,TPP1,SULT4A1,CRMP1,CSNK1E,PDE4DIP,DGKG,EDNRB,STX2,BAIAP2,HPCAL4,FYB1,INPP5K,GNAO1,GPD2,LILRA2,CACFD1,GSTM5,ICA1,LSS,MSR1,NF1,MINDY2,PPP2R2B,RGS3,FBXO11,SP4,IZUMO4,PEG10,SPTB,STX1A,TBCEL,CRTC1,TUBB1,RPRM" Drug 2838_UP Etifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "BIN1,PPFIA3,PLA2G4C,CFLAR,BAIAP3,PICK1,NCOR2,SPOCK2,ZNF804A,TSPAN5,EGR3,TNK2,FGFR1,AGAP2,FAM49B,SEPT9,MSL3,GRIK5,IL6ST,INPP1,JAK2,KCNN1,MAP4,ADAM22,SLC11A2,PDE4B,LRP12,MINDY2,PPP2R2B,PRKAR1B,EPN2,PKNOX2,KDM4B,SOX3,ZC4H2,SMG6,UBE3A,SPHK2,EPM2A" Drug 4758_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NME5,AMT,CFAP410,ARHGEF2,FOXN3,TAOK2,WHRN,RCHY1,CNTNAP2,RIMS2,MFAP3L,PARD6A,EGFR,ST3GAL6,FGFR1,AFF2,GAD1,GRM8,SLC2A6,HNMT,LMO2,MEF2C,MID1,AFF1,GIT1,ADAM22,MYT1,NF1,NFYA,RETREG1,PRKAR1B,ZSCAN32,KCTD17,ZNF821,FNDC3A,SMARCD3,ZNF423,TMEM121,SPHK2" Drug 971_DN oxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "MPDZ,BMP7,SYNJ2,CA12,CCNT1,ARMC8,DCAF8,HDAC4,PARD6A,ABCC5,EGR3,RRAGB,EFCAB2,INPP5K,SRCAP,CNTRL,IL6ST,MAP4,MEIS1,SCAMP5,MPP2,CNOT4,PIK3R1,KCTD15,SMOX,PMP22,ELOVL2,RET,FERMT1,ABLIM3,PEX26,PPP4R3A,DIP2A,COBL,ANKRD12,KAT6B,LMF1,ZNF74,ZNF142" Drug 4738_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG3,TRMT9B,BIN1,PLA2G4C,STX16,GYG2,CFAP410,NFS1,QKI,WHRN,GREB1,DOCK4,MFAP3L,EDNRA,COQ7,RRAGB,ACSL4,SEPT9,GCNT2,TDRKH,TJAP1,MMP16,NPTX1,MBOAT7,WDR25,PTK2,CEP97,ATXN7,ASAP3,ARHGAP26,CLSTN2,NSFL1C,PLCB1,ASTN2,EXOC7,TNS2,THRA,TNS1,EPM2A" Drug 3370_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADD2,ADORA2A,BIN1,OGT,N4BP2L1,CAMK2B,TAOK2,RAB33A,SEC14L5,SPOCK2,HS3ST2,DPP6,MBNL2,ING4,RASGRP2,PIPOX,FLNC,GCNT2,GPER1,RASSF8,IGF1,LMO2,MMP17,MSR1,NTRK2,CEP41,PRKCB,STUM,ZC3H13,SPTB,NFASC,ZC4H2,ARC,WSCD1,PCDHGA10,HEY1,FLRT2,SLC17A7,KCNAB1" Drug 2067_UP Ursolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ALK,TRMT9B,APBB2,MPDZ,MYRF,CACNA1A,CARS,LARGE1,SLC4A8,CSF1,DZIP3,BRINP1,DPH1,EDNRA,ING4,MTSS1L,EZH1,BAIAP2,OGA,SIGLEC8,DISC1,SRCAP,MSL3,SHISAL1,KPNA5,RETREG1,ZCWPW1,FBXW7,TRAPPC13,SATB1,SUPT20H,KDM4C,CEP68,DIP2A,FBXW11,SMG6,RPGRIP1L,ZNF24,SPHK2" Drug 4786_UP Atovaquone [95233-18-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADCY6,FZD9,SEMA6A,CDC42BPA,APC,GAS7,N4BP2L1,ADGRB3,CACNA1I,CA4,TAOK2,CNTFR,CSF1,RGS6,VCAN,F5,ACSL4,ZNF589,AFF2,GCNT2,GPR75,POLL,INPP1,AFDN,MMP17,NF1,ENPP2,ZSCAN32,KHDRBS2,FRMPD1,PKNOX2,IZUMO4,HECW1,SPP1,ATP10B,ZC4H2,EXOC7,ZNF711,PHTF2" Drug 1179_DN "ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADRB2,MTUS1,OSBPL1A,C1QTNF3,ZSCAN18,NUMB,ADAM23,CFLAR,SCAPER,LDLRAD4,THSD7A,TPP1,RUBCN,ZFYVE16,SPATA2,ENO2,ZNF589,FYB1,TXNL4A,MAP4K5,MEF2C,PIK3R1,PLEC,PLTP,SEC14L1,GALNT10,SH3BP2,ZKSCAN3,SPATA7,ZSWIM8,CDK19,CABIN1,WBP2,ZBTB14,ZNF45,ZNF74,REEP1,MAP3K12,AAAS" Drug 2735_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "C1QTNF3,APAF1,FAM131A,PPP4R4,CASK,FOXN3,QKI,HOMER3,CREM,SLITRK5,USP6NL,DTNA,E2F5,HIPK3,EGR3,KAT8,ZNF589,PRKAG2,IQCG,NBEA,INPP5K,LILRA2,IL6ST,MEF2C,NINJ2,CCSER2,RETREG1,POU6F1,ZFHX4,TCP11L1,CLIP1,TMCC1,TROVE2,ADGRL3,ZNF34,TRPS1,SSBP2,ZNF225,URM1" Drug 4623_DN Hymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "APC,PDE8B,ATP2B2,SYNJ2,LDLRAD4,CFAP410,ABCG2,CREM,NCOR2,DZIP3,GPRASP1,RUSC2,SGSM2,RCAN1,DTNB,MBNL2,RGS17,ANKFY1,DENND2A,SIGLEC8,CACFD1,TJAP1,FAM69A,NEK1,OCRL,PALM,ZSCAN2,TMEM231,FAT4,RAP1GDS1,DCUN1D2,KIRREL1,RBM34,IQSEC2,TIAM1,TK2,EMSY,VPS35L,MPPE1" Drug 7523_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "BIN1,CDC42BPA,PPFIA3,CDK13,EIF4G3,CA4,CAMK2G,ARHGAP33,CSF1R,RIMS2,GIT2,DBN1,DTNB,TOM1,PHF20L1,DLC1,ZNF589,FER,FGFR1,GRB10,DHX35,IL6R,LIG4,SMAD1,MMP17,NF1,CDK18,DCUN1D2,GSTCD,TCP11L1,RPS6KA2,NXT2,JMJD6,PCDHA5,ZNF34,SPHK2,TFIP11,FIP1L1,RNF170" Drug 4221_DN Tolnaftate [2398-96-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "ADCY6,CFLAR,ST3GAL5,SPAG9,QKI,BAG4,SLITRK5,CTH,ARHGEF4,PLPPR4,MBNL2,SPEG,ETV1,ANKMY1,POLR1B,PDLIM5,DENND2A,GLI2,SHISAL1,IL6ST,FAM69A,JAK2,TAGLN3,NDP,PIK3R1,RETREG1,SNRK,ZSCAN32,PTPRN2,RAD51D,FUZ,FBXO11,ST6GAL1,NLGN1,LIMCH1,ZNF34,WIPF1,KCNAB1,EPM2A" Drug 3245_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "NDRG2,NME5,BIN1,CDC42BPA,APLP1,PPP4R4,PDE8B,MARK4,SCAPER,BAIAP3,LDLRAD4,TPP1,CNTN1,WHRN,CRMP1,DMPK,MTSS1L,DISC1,STON1,GPER1,AFDN,MSR1,CDK18,PDE4D,MAPK7,RGS12,RPS6KA2,ASAP3,SMARCC2,ARHGAP26,CLSTN2,SUPT5H,ARC,ZNF34,CDK20,WBP2,VLDLR,KCNK12,ITM2C" Drug 5362_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.71E-04 1.00E+00 3.04E-03 3.43E-02 39 194 "AP2A2,CDC42BPA,PPFIA3,ARHGDIG,BCL7A,BAIAP3,CARS,CLOCK,CRY2,PPP6R2,EDN3,EZH1,BAIAP2,CAMKK2,DISC1,SEPT9,GFER,POLL,DHX35,KCNF1,IPO5,ZNF862,POLG,TMEM104,RIPOR1,RGS12,RPS6KA2,SH3BP2,SLC2A5,SMARCC2,ZSWIM8,PLCB1,ARC,TRIO,ZKSCAN5,PLPPR2,VIPR2,EVI5,HPS4" Drug 5802_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.72E-04 1.00E+00 3.05E-03 3.44E-02 37 181 "ADRB2,NME5,EPB41L5,ARNTL,MARK4,ADGRB2,ST3GAL5,WHRN,ABCG1,PDE4DIP,CTH,JAKMIP2,PLPPR4,EDN1,RGS17,TAOK3,FYN,STON1,GSN,KCNH2,MEF2C,MMP16,TAGLN3,PCDH9,PFKFB4,SERPINI1,PTCH1,ENOX1,RGS4,SH3GL3,WDR47,THSD1,ELOVL4,RGL1,SYT1,COBL,PLSCR4" Drug 3106_DN Chrysin [480-40-0]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.72E-04 1.00E+00 3.05E-03 3.44E-02 37 181 "MTUS1,AMPD3,CDK10,ARRB1,MARCH3,NCOA1,FUBP1,HDAC9,TUBD1,GPHN,ERCC2,ZNF589,PCYOX1,SYNCRIP,POMT1,PDLIM5,INPP5K,MSL3,ATXN2L,AGBL5,IRF8,IFI16,ITGA7,KCNN2,NEK1,OGG1,PDE4B,HSPA4L,ARHGEF40,SPTAN1,ZC4H2,KLHL7,TCF4,SYNE1,PARD3,ZBTB14,ATP6V0E2" Drug CID000012967 N-ethyl-N-nitrosourea Stitch 2.85E-04 1.00E+00 3.19E-03 3.59E-02 51 275 "APC,ARNTL,BLM,RUNX1T1,LRBA,RCBTB2,CHRNA4,QKI,HECTD1,AHCTF1,CRY2,TRIM69,CHRDL1,MED12,PHC2,EGFR,ENO2,COQ7,ERBB2,ERCC2,F8,FECH,GAA,GCK,ATE1,RBPJ,ITPKB,AQP11,KITLG,MITF,MX1,MYO7A,NBL1,NF1,PDE1B,ZNF655,PTCH1,RASGRF1,FBXW7,SARS,SUPT20H,SMARCA4,SMARCD3,DDN,SIRT1,ZFPM2,TSC2,CELF4,SMARCAD1,TUBA1A,IFT88" Drug 3241_UP Etoposide [33419-42-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-04 1.00E+00 3.22E-03 3.63E-02 38 188 "CDK13,STX16,CFLAR,NCOR2,RIMS2,ARMCX2,EDNRA,CDKL3,ZNF589,SIGLEC8,SRCAP,SESN1,POLL,IRAK3,INPP1,INPP5B,KCNN1,MAN2A2,TAGLN3,TREM2,MTRF1L,PRODH,PTPRB,NKAIN1,ZFHX4,CARF,TCP11L1,ZFP2,ASAP3,PEX26,SLC14A1,SLC22A4,ASTN2,ZEB1,GPR161,ZMAT3,SLC30A4,DNALI1" Drug 6451_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-04 1.00E+00 3.22E-03 3.63E-02 38 188 "ARRB2,KRIT1,MAGI1,SRSF11,EPS15L1,RAB26,DCAF8,KIAA0586,MFAP3L,PARD6A,VPS13B,STX2,SYNCRIP,CINP,STON1,GPER1,ITPKB,JAK2,MAP4,MEIS1,MMP16,MPP2,NCAM2,PKIA,RIPOR1,ZDHHC14,NEK11,ERC1,CLASP2,TTBK2,SYT1,TACC1,KAT6B,RUNDC3B,SSBP2,UBTF,XRCC4,REEP1" Drug 3480_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-04 1.00E+00 3.22E-03 3.63E-02 38 188 "CAMK2G,EPS15L1,QKI,AKAP12,FAM169A,GREB1,MFAP3L,RHOBTB1,RASGRP1,EGR3,EIF4G2,SEMA4D,FAM49B,GLYR1,POLL,GNG4,LPAR4,HNMT,IL6ST,JAK2,MAP4,MITF,MMP16,PDE4A,RETREG1,MBOAT7,ZSCAN32,RAD51D,RET,SGK1,RBM34,SOX3,CDK19,SPART,DIP2A,TIAM1,CDK20,KCNK12" Drug CID000005291 imatinib Stitch 2.91E-04 1.00E+00 3.26E-03 3.67E-02 73 430 "CLK4,BRAP,PCDH10,ALK,APLP1,BMPR1B,BTK,JAZF1,CACNA1I,DDR1,RUNX1T1,ARHGEF2,ABCG2,CNTFR,CDC42BPB,NCOR1,CSF1,CSF1R,CSF2RA,PDE4DIP,HDAC9,MAML1,GIT2,EGFR,TNK2,EPHB1,ERBB2,ERBB4,PTK2B,FER,FGFR1,FGFR3,FOXO3,FLT1,FYN,MSTN,GFRA2,CIT,PTPRT,HBA1,BACH2,IGF1,IL6ST,JAK2,KIT,LIFR,MATK,KITLG,NF1,NPY,NTRK2,NTRK3,ABCB1,PIK3C2A,PIK3R1,PPP2R5E,MAPK3,MAPK9,MAPK10,LAMA1,PTK2,RAP1GDS1,RET,BAALC,PPM1E,MYO18A,SLA,CDK5RAP2,TEK,ACTR6,SMUG1,TUBB2A,FIP1L1" Drug CID000001003 phosphate Stitch 2.91E-04 1.00E+00 3.26E-03 3.67E-02 240 1716 "ABR,KDM5D,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADRA1B,AP2A1,AP2A2,NME5,AK2,ARHGAP20,AMPD2,AMPD3,OGT,NT5C3B,PPFIA3,CDC14B,ARHGDIA,ARRB1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,BARD1,BCHE,BLM,SYNJ1,SYNJ2,MTMR3,MTMR2,AP1M1,GYG2,CA4,CALM1,CARS,CBS,KYAT1,CCNH,CCNT1,ENTPD2,ENTPD6,DGKI,LRBA,CDC25B,TIGD7,COPB2,CHN1,CHN2,PLEKHB1,CNOT8,ARHGAP22,MYL6B,CLTB,CLTC,NGEF,PCYT1B,COL4A5,CPS1,ENTPD4,GDA,ABCG1,CRYM,CS,SEC24C,CSNK1E,CSNK1G3,PLCXD3,ARHGAP32,ARHGAP24,EARS2,DGKB,DGKG,DAPK3,IP6K1,RHOBTB1,DMD,DNM1,DTNB,DUSP9,DNM1L,EDN1,EDN3,TMTC1,FAM13A,EGFR,RASA4,EIF4G1,EIF5,TUBD1,ENO2,EPB41,ERCC2,KATNAL1,F8,TUBA1B,TUBB3,PPP1R1B,FECH,SEC24B,ATP5PD,IP6K2,VTI1B,SLC37A3,FOLH1,AK8,ATP6V1H,ATP2C1,MTHFD2,INPP5K,ACSS1,GATM,GCK,TUBA8,CYP46A1,GFER,GGT7,GGT5,DBF4,GLUL,GNAL,GPD1,GPD2,PLCD4,GSN,MAP4K5,HBA1,TNFAIP8L3,ARHGAP36,HP,IDH3A,IDH3B,MYLK2,IGF1,INPP1,ITPKA,ITPKB,KHK,LIMS1,MAP2,MAPT,MAT2A,MBP,MYH3,NBL1,NEFM,NEFH,NME4,OCRL,OGG1,P2RY1,PDCD2,ENPP2,PDPK1,PFKFB2,PFKFB3,PFKFB4,PGAM2,ABCB1,DUSP26,PKM,PLCB2,PLCD1,PLEC,PLIN1,SLC25A23,POLR2F,PPM1B,PPP1R1A,PPP2R2B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,PPP5C,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PSMA6,PTH1R,PTPN13,PTPRB,PTPRD,PTPRE,PTPRG,PTPRN,PTPRN2,PTPRO,ACSS3,RASGRF1,RDX,DUSP15,RGS3,RNASE1,NUDT11,RPE,RPL15,ATP8B4,RPS20,RYR3,SALL1,SARS,COPZ1,RASA3,PPM1E,SEPHS1,SIRT2,ARFGAP1,SPP1,ARHGAP26,SST,ADHFE1,SUPT5H,ARHGEF9,PLCB1,SYN2,TAF6,TAF9,SIRT1,TIAM1,TK2,NPL,TRIO,NEIL2,TUBB2A,TUBB1,PLPPR2,VAV1,SPHK2,PRTFDC1,TUBA1A,SLC17A7,PLD4,EPM2A" Drug CID000166928 AC1L4YZD Stitch 2.98E-04 1.00E+00 3.34E-03 3.76E-02 6 10 "LHX2,CTH,IGSF6,MAT2A,RDX,CLSTN2" Drug 3378_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADORA1,BEGAIN,BIN1,APAF1,APBA2,KCNAB2,APBB2,DNAH17,MTMR3,CA4,CAST,LDB2,CACNA2D2,AKAP5,CPS1,KLHL3,FHL1,GFER,GRIK5,HLF,TJAP1,MAP2,MEF2C,MID1,ADAM22,NOVA2,NPR2,PPP5C,PRKCB,SAMD9,VPS13C,ZDHHC14,RFX2,SEMA6D,ATP10B,PIK3R5,TPM2,LMF1,EPM2A" Drug 2975_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "MTUS1,CFLAR,FUBP1,CFAP410,SCARB1,ARHGAP33,TAOK2,CREM,CSNK1E,ZNF337,DCTN1,E2F5,RASGRP2,PTK2B,OLFM1,PRELID3A,SIGLEC8,PADI2,ATXN2L,KHK,AFDN,ADAM22,MSR1,CNOT4,OXTR,PPP5C,CEP41,TMEM104,PTPRN2,SEMA6D,GALNT10,ST6GAL1,SNCA,KANK1,PDLIM2,ADGRL3,PARD3,FLRT2,ZNF142" Drug 2411_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AP2A2,MTUS1,TRMT9B,PKP4,APC,C5,CLCN3,VCAN,PPP6R2,ZNF337,TM9SF4,CNNM1,EIF1,DLC1,AGAP2,PDLIM5,ERAP1,GATM,RUNDC3A,ICA1,MEF2C,SCAMP5,P2RY1,PLCD1,PPARA,RIPOR1,RGS4,RGS12,CLIP1,GALNT10,FERMT1,SS18,TACR1,PDLIM2,AP4E1,R3HDM1,TNS1,MAP3K12,EMSY" Drug 2733_UP Methazolamide [554-57-4]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADRA1D,BBOX1,TRMT9B,PTCH2,ALDH7A1,AZGP1,KSR1,COL9A3,HAPLN1,SEZ6L2,HEYL,EGFR,CORO2B,ZNF44,SIGLEC8,SEPT9,MSTN,GRM8,MGAT3,MID1,AFDN,NOVA2,NTRK3,PCSK5,PTPRB,SUGCT,NEK11,SCN2B,NLGN1,SPART,SYT1,TAL1,TIAM1,TRIO,VIPR2,LMF1,ZNF711,FAM13C,TIGD6" Drug 6977_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASPHD1,TRMT9B,BIN1,ARHGEF1,CHN2,EPS15L1,VAX2,QKI,PDE4DIP,PHF14,MED12,CNNM1,ENO2,COQ7,ANKMY1,ZNF589,FER,ANKFY1,RAB30,GPR37,INPP5B,ITPKB,MSI1,PDE4B,PTPRE,SBF1,ZNF821,ZKSCAN3,RBM34,UNC5B,ELOVL4,STX1A,ARC,ASTN2,SLC30A3,EVI5,ITM2C,EPM2A,RNF146" Drug 3910_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "BRAP,LTBP4,BIN1,SEMA7A,CDK13,HIP1R,MAGI1,SOCS6,LHX2,PLAA,STOML1,RIMS2,SUGP2,DLL3,GAD1,ERAP1,GCNT2,RUNDC3A,ICA1,MAP2,NF1,CNOT4,NPR2,LRP12,PRKAR1B,CNNM2,NKAIN1,SH3BP2,FERMT1,LIMCH1,SNCA,LHPP,VPS13A,KIAA1107,WSCD1,RPGRIP1L,HEY1,PARD3,PLPPR2" Drug 3942_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABCD2,AMH,AMT,PDE8B,ATP2B2,N4BP2L1,ADAM23,RGS11,KSR1,EPS15L1,RAB33A,SPOCK3,TNK2,ELN,LRRC17,ERCC2,CDKL3,DLC1,OLFM1,FLNC,ALDH1L1,CSDC2,POLL,AP4S1,GUCY1B1,MGAT3,ZNF862,NTRK2,PFKFB2,PTH1R,FRMPD1,ST6GAL1,SLC2A5,JMJD6,TNS2,THRA,ADAMTS9,TIGD6,AP3B2" Drug 3859_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AP2A2,DOC2A,AMH,GYG2,BAIAP3,CBFA2T2,CRLF1,FOXN3,RIMS2,PPP6R2,TOM1,MBNL2,EZH1,BAIAP2,INPP5K,ALDH1L1,GFER,GRIK5,MATK,ADAM22,NF1,NTRK2,PLEC,LRP12,MINDY2,FAM184A,ENOX1,MAPK12,SBF1,SH3BP2,SPTAN1,IQSEC2,ST5,ASTN2,KIAA1107,R3HDM1,FAM155A,VIPR2,LAT2" Drug 364_UP trichostatin A; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABHD6,NDRG2,OGT,NCOA1,SCAPER,CACNA1I,CAST,CD86,CBFA2T2,RAB26,GIT2,SV2B,PLXNC1,STX2,FGFR1,FYN,RUNDC3A,BTN2A1,SOX21,HNMT,IFI16,MAP4,MEF2C,FXYD7,NEK1,NNAT,PDE4B,SERPINI1,GPSM2,PLEC,FUZ,TSPYL2,POGZ,STX1A,TBL1X,TCF4,PLPPR2,SLC17A7,PCBP4" Drug 3829_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "TRMT9B,KCNAB2,PPP4R4,PLA2G4C,CHRD,KSR1,SLIT2,RAB33A,SULT4A1,CNTN1,CSF1R,DAPK1,DAPK3,SPOCK2,EDIL3,CALCRL,ERCC2,PTK2B,FGFR1,CAMKK2,CSPG5,TMEM8B,GDF9,HPGDS,INPP5B,LSS,NF1,NNAT,PCBP3,OPRL1,GPR85,PPARA,RFX2,KCTD17,CRTC1,LAT2,PRDM10,PARP11,NLRP3" Drug 4576_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASPHD1,SYN3,FAM135A,TRMT9B,CDK10,PPP4R4,NRP2,GYG2,CACNA1I,CACNA1G,CA4,SLC16A4,CD86,CRLF1,SULT4A1,CNTFR,VCAN,SPOCK2,AASS,RASGRP2,ADAM22,NOVA2,MINDY2,GDPD2,ZMAT4,CARF,FRMPD1,NLGN1,SLA,SLC8A1,SLC11A1,OGDHL,SNAP25,TSNAXIP1,RBM26,ATP10B,PCDHGA10,HIF3A,SLC17A7" Drug 6514_DN Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASPHD1,ABHD6,DOC2A,BIN1,APC,APLP1,MPDZ,SYNJ2,MAGI1,CACNA2D2,CREM,DAPK3,MFAP3L,ING4,F8,DISC1,TXNL4A,GNG4,STON1,GPR37,CNTRL,ITPKB,NF1,NFYA,NKAIN1,SAFB,ZNF821,SYBU,PEX26,EPN2,THSD1,NXT2,ASTN2,RPGRIP1L,TPM1,HIRA,FAM155A,PLPPR2,CLDND1" Drug 1731_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASIC1,NDRG2,AMT,CDC42BPA,CAMK2G,KYAT1,AP4M1,TAOK2,SLIT2,CLCN3,CNTFR,AKAP7,SPOCK2,DTNA,EPHB1,OLFM1,INPP5K,ALDH1L1,USP19,PRRC2B,NXPH3,ITGA7,KIF5A,MGAT3,NF1,NFYA,NTRK3,MAPK3,PTPRN2,ATXN2,SH3BP2,CCDC88A,KBTBD4,MAPKBP1,DBNDD2,PLCB1,SZT2,PARD3,MARCH8" Drug 325_UP radicicol; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AGT,SYT13,MPDZ,BCL7A,KRIT1,CRMP1,ARHGEF10,RCAN1,SUGP2,BAIAP2,SMC2,PDLIM5,B4GALNT1,AGBL5,HSF2,ICA1,KTN1,L1CAM,ADAM22,PTOV1,NEK1,NNAT,CDK18,SMIM7,MBOAT7,PRODH,RGS3,HSPA4L,KDM4B,VPS13A,ANKRD28,CLASP1,TNS1,TRIO,UBE3A,PLPPR2,ZIC1,ZNF189,MAP3K12" Drug 2853_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "KIAA1324,AK2,BIN1,SLC2A11,CFLAR,MTMR3,CFAP410,EPS15L1,CREM,GREB1,SNPH,RASSF2,SPOCK2,ARMCX2,TMCC2,DTNB,ZNF589,FGFR1,FAM49B,KHDRBS3,GAD1,GSN,SYNPO,KCNH2,MMP16,NNAT,MINDY2,PRKAR1B,MAPK7,SBF1,ASAP3,SNCA,HECW1,PLCB1,ANKRD12,SPHK2,EVI5,GDPD5,ITM2C" Drug 5053_DN Antimycin A [1397-94-0]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ACTN1,NME5,KCNAB2,PPFIA3,MARK4,SCAPER,CBFA2T2,CSF1R,VCAN,HDAC9,TBC1D5,EIF5,HSD17B14,BAIAP2,CINP,TMEM8B,CNTRL,BACH2,KPNA5,LRP12,BCAS3,SH3TC2,RPS6KA2,SUPT20H,ZFP30,DZIP1,BTBD7,ZHX3,PBLD,ELOVL4,ARHGEF9,SYT1,SLC35G2,TRPS1,UGT8,PLPPR2,SPHK2,TFIP11,EPM2A" Drug 4300_UP Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADORA2A,PKP4,PDE8B,N4BP2L1,RIMS2,DTNA,EDN1,MRNIP,F5,DLC1,KAT8,ZNF589,TRMO,RUNDC3A,GNG4,MCHR1,FAM107A,IL6ST,KHK,KITLG,AFF1,GIT1,ADAM22,MSR1,PCBP3,GPR85,PFKFB4,PRPH,VPS13C,RET,RGS12,DZIP1,SLC11A1,ZNF667,MCF2L2,TACR1,TCF4,UBE3A,LAT2" Drug 3082_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "RALGAPA1,AMPH,PLA2G4C,ARSE,CACNB4,CBFA2T2,CLGN,FAM149A,SH2B1,ABCG1,RUSC2,CALCRL,RCAN2,DLL3,GPR75,GNAL,PCLO,ATXN2L,ICA1,KCNJ5,KCNQ3,KHK,MAP4,MX1,NOVA1,CLDN11,PFKFB4,LRRN3,PRKAR1B,CNNM2,BCAS3,RFX2,ZFHX4,FAM102A,KDM4C,ARHGAP26,SPART,TROVE2,CLIP2" Drug 419_UP chlorpromazine hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG2,AMPD3,BIN1,APC,APOC1,DNAH17,AATK,ARHGEF4,KIAA0586,DYNC1I1,DRP2,SUGP2,MBNL2,TNK2,EPHB1,HPCAL4,CYP46A1,RUNDC3A,SOX21,SLC2A6,ITPKB,MAP4,TM6SF1,MMP17,MX1,PLEC,SMOX,ZNF821,SH3BP2,FNDC3A,SLC6A8,LMO3,PHLDB1,ANKRD12,EXOC7,CLIP2,WNT7A,SLC17A7,KCNAB1" Drug 3634_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "SYN3,ADD2,ADORA1,LTBP4,CDC42BPA,AZGP1,CAMK2G,USP2,CBFA2T2,FOXN3,TPP1,NRG2,CNTNAP2,DBT,TMCC2,HSD17B14,ERCC2,ANKMY1,PTK2B,GABRG2,CSDC2,RUNDC3A,GRM2,INPP5B,MGAT3,MN1,ADAM22,MYT1,NF1,PALM,SAMD9,SBF1,SLA,SLC11A1,WSCD1,TRIO,CLIP2,SLC30A3,AP3B2" Drug 4784_DN Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADCY6,DOC2A,EPB41L5,PPFIA3,RIPK1,CFLAR,CA12,SPAG9,SLIT2,HOMER3,AKAP7,SH2B1,LRIG1,HDAC4,GIT2,DCTN1,DTNA,MRNIP,EPB41L2,AHDC1,CACFD1,IL6R,IL6ST,MITF,PLEC,MBOAT7,FSD1,PRKAR1B,NKAIN1,ATXN2,ZNF821,SH3BP2,MAPKBP1,SPTAN1,NSFL1C,ASTN2,TMEM121,UBTF,KLC2" Drug 7323_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASPHD1,ABHD6,SRPX,BIN1,CDK13,PDE8B,ATP2A2,BCL7A,SCAPER,MTMR3,CACNA2D2,HOMER3,MFAP3L,PARD6A,DUSP9,EIF4G2,EPHB1,SIGLEC8,SRCAP,POLL,PRUNE2,CNTRL,HAS2,MGAT3,MSI1,NF1,LRP12,KHDRBS2,SBF1,PREX2,LIMCH1,PHLDB1,ARHGEF9,DICER1,AP4E1,ZNF34,HEY1,FAM155A,WIPF1" Drug 6959_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABHD6,CDC14B,MTMR2,CA12,SPAG9,LHX2,HOMER3,ARMC8,CREM,SOCS5,DBT,MFAP3L,FBXL5,PARD6A,DTNA,MAMLD1,IRAK4,FGFR3,ARFIP1,FERMT2,GRB10,FICD,ATXN2L,HNMT,JAK2,KCNF1,MMP16,GIT1,NEK1,OXTR,PPP3CC,PTPN13,RIPOR1,CCDC25,SAFB,TMPO,TRIO,LMF1,ZBTB38" Drug 2173_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG2,TAOK2,DZIP3,ZNF337,GSDME,DTNA,FAM13A,EIF1,TUBD1,ENO2,CD320,F5,NBEA,TPK1,GALC,SEPT9,POLL,LILRA2,PADI2,SMAD1,SCAMP5,ZNF862,NEK1,PPP5C,PTCH1,RIPOR1,TCP11L1,MAP6D1,KDM4B,TSPYL2,DDN,LARP4,R3HDM1,TPM1,ZKSCAN5,PLPPR2,UBE3B,PHTF2,SENP7" Drug 5967_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ALK,AMH,APAF1,FAM131A,APOC1,PLA2G4C,CFAP410,CBFA2T2,SCARB1,FOXN3,NECTIN3,CRMP1,DBN1,EGFR,ERCC2,F5,SCARA3,GALC,GFER,USP19,TDRKH,GPER1,CNTRL,KCNH2,MYCN,PCDH9,WDR25,ELOVL2,SLC4A3,PPP4R3A,SNCA,KDM4B,TACC1,CHST8,ZBTB14,NDRG4,TFIP11,SLC30A3,KAT6A" Drug 3843_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASIC1,ACTN1,NDRG2,AP2A2,CDC14B,SPTBN4,CAMK2B,CCNT1,CDH2,LHX2,EPS15L1,PICK1,WHRN,CRY2,DAPK3,TMCC2,ING4,ERCC2,SPEG,ANKFY1,CAMKK2,FUT9,NEU3,SRCAP,GLYR1,POLL,GPD2,GRIK5,GSN,LSS,KITLG,AFDN,NF1,PPARA,COA1,SNCA,PEG10,ZC3H13,GPR161" Drug 3844_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ALK,BEGAIN,SEMA7A,PRX,MTMR3,MYRF,CALB1,HIP1R,SLC16A4,PICK1,AKAP5,NCOR2,DAPK3,DYNC1I1,SHANK1,ING4,ERCC2,DLC1,CAMKK2,SRCAP,GLYR1,GPER1,GSN,HLF,ICA1,LSS,NCF2,TREM2,TMOD2,PPARA,MASP1,KCTD17,ST6GAL1,RBM34,HECW1,ARC,SYT5,FLRT2,KAT6A" Drug 3454_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "KDM5D,NME5,AMT,GAS7,APOC1,ATP2A2,SLC2A11,ATP6V0A1,CFLAR,GYG2,ENTPD6,ENTPD4,SH2B1,ARHGEF4,GIT2,EGFR,SCARA3,PDLIM5,TPK1,GAD1,HLF,ELOVL5,TJAP1,MAP4,MPP2,PALM,POLG,CNNM2,CARF,RPS6KA2,SH3BP2,FAM214B,ELMO2,ZHX3,CDK19,TCF4,OBSL1,ZKSCAN5,NT5M" Drug 2472_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "BIN1,APAF1,BCL7A,HIP1R,FOXN3,PLAA,STOML1,ABCG1,DTNA,PIPOX,ST3GAL6,IQCG,EFCAB2,POMT1,OGA,FYB1,SEPT9,POLL,ATXN2L,TJAP1,KIF2A,MAP4,NFYA,PLCD1,PTN,RIPOR1,ZCWPW1,MRAS,SLC11A1,SNCA,TROVE2,SEPT8,ARHGEF9,ADGRL3,KIAA1107,XRCC4,ZNF24,MAP3K12,TIGD6" Drug 4792_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADORA1,AK2,AMH,APOC1,PPFIA3,NRP2,KSR1,CD86,ARHGEF2,CHRNA4,SULT4A1,COL9A3,EGR3,IGSF6,DLC1,FGFR1,PDLIM5,FYB1,POLL,SPACA9,GRM8,IL6ST,INPP5B,KCNH2,KCNN1,KIF5A,PALM,GPR85,CRTAC1,EMID1,SNCA,ZC3H13,TAL1,TRIM2,GPR161,R3HDM1,TRO,ADAMTS9,SEMA3B" Drug 2748_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "APBA2,PPFIA3,PLA2G4C,ATP2A2,ST3GAL5,BAIAP3,LDLRAD4,ARHGAP33,SULT4A1,HOMER3,NRG2,DOCK4,DBN1,ZNF804A,SPOCK3,DNM1,EDNRB,CDKL3,GFER,STON1,GSN,KHK,MAP4,GIT1,PALM,PLCB2,ZDHHC14,KCTD17,RPS6KA2,SH3BP2,CPEB3,SNCA,HECW1,KIAA1107,TNS2,CHST8,UBE3A,VIPR2,WIPF1" Drug 2897_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ASPHD1,FAM131A,CDC14B,SLC2A11,GYG2,CACNA1I,CALB1,CAMK2B,CAMK2G,PICK1,CNTN1,CNTNAP2,GSDME,SUGP2,ZMYND10,OLFM1,FLNC,TMEM8B,NEU3,SRCAP,ADAMTS13,FAM107A,SLC2A6,ITPKA,KIF5A,PLTP,RGS12,RPS6KA2,KCNIP1,SCN2B,AMBRA1,KANSL3,CCDC88A,SLC9A5,BTBD7,ARC,TMEM121,LAT2,GDPD5" Drug 6310_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AP2A2,MTUS1,APC,FAM131A,MARK4,RIPK1,CCNT1,SEPT7,QKI,CNTNAP2,PPP6R2,TM9SF4,SPOCK3,EIF5,ING4,ANKMY1,FCGRT,BACH2,ZNF862,NDP,CNNM2,ELOVL2,SH3TC2,RPS6KA2,SBF1,FAM102A,ASAP3,FUZ,ERC1,KIAA0930,TMEM121,ZNF34,METTL3,TSC2,PLPPR2,TFIP11,MAP3K12,TIGD6,AAAS" Drug 4433_DN 2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "RALGAPA1,CDC42BPA,APC,APOC1,ADAM23,BAIAP3,LHX2,NRXN3,CREM,AATK,VCAN,SLITRK5,RUSC2,SPOCK3,ECM2,ING4,NCALD,SCML2,PRELID3A,GRIK5,PADI2,ICA1,KCNJ5,MAPT,MIA2,MMP16,NF1,PFKFB4,PLCB2,WDR25,CNTLN,SPTB,LHPP,TROVE2,TBCEL,TIAM1,TNS1,VIPR2,EVI5" Drug 1960_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "PKP4,GAS7,APLP1,CFLAR,SLC25A14,CBR1,FOXN3,AKAP12,NCOR1,CSNK1E,DPH1,ACSL4,FCGRT,FHL1,SEC23B,GAA,DENND2A,RNFT2,HNMT,L1CAM,MAP4,MBNL1,MBOAT7,QDPR,GAL3ST4,NUDT11,CLIP1,ATXN2,AMBRA1,SMARCC2,CDK5RAP2,MAPKBP1,TSPYL2,PHLDB1,NSD1,HEY1,UBTF,SMIM8,LAS1L" Drug 5348_UP Bisoprolol fumarate; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ALCAM,AMT,APC,APOC1,PPP4R4,SLC4A4,BCL7A,CFLAR,GIT2,MFAP3L,KAT8,FHL1,GAD1,TXNL4A,HNMT,DHX35,INPP5B,KCNF1,KHK,MAP4,MIA2,MMP16,MPP2,GIT1,NEK1,NNAT,STRN3,MINDY2,SH3BP2,NLGN1,ANKRD6,BTBD7,ARC,RPGRIP1L,RUNDC3B,ZNF24,GDPD5,HPS4,MPPE1" Drug 4223_UP Nystatine [1400-61-9]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AMPD3,PPFIA4,APC,ADGRB2,KSR1,BMP7,CAMK2B,CCK,CBFA2T2,ARHGAP33,PLEKHB1,CABP1,CNTNAP2,EDN1,EDN3,HEYL,AASS,SRPK3,MTSS1L,AGAP2,SIGLEC8,GPD1,AP4S1,ADAM11,MSI1,ADAM22,NPTX1,PPARA,LRRN3,SUSD4,PBRM1,SLC4A3,SLC6A11,SLC8A1,IZUMO4,IQSEC2,RBM26,CABIN1,SLC17A7" Drug 2087_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "BIN1,SEMA4G,SLC4A4,ADGRB2,SYNJ2,CDH2,TBRG4,SRSF11,FOXN3,STOML1,PDE4DIP,PPP6R2,RUBCN,MAMLD1,EDNRA,FAM13A,COQ7,PRRC2B,SLC2A6,SHISAL1,ITPKB,KIFC3,POLG,PRKAR1B,PTN,SH3TC2,TCP11L1,RXRA,SLC4A3,LIMS2,RBM34,IQSEC2,LHPP,MCF2L,IQCE,TMEM121,CABIN1,SPHK2,HPS4" Drug 4536_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADCY6,ADORA2A,AMH,CBS,SEPT7,TPP1,SH2B1,NCOR2,CSF1R,CNTNAP2,DZIP3,ARMCX2,DMPK,AASS,TNK2,ZNF589,FGFR3,AGAP2,DCTN2,SYT17,GLI2,LSS,TM6SF1,PDE4D,GRAMD1C,PRPH,PTPRN2,BEND5,KLHL11,FAM102A,SMARCA4,ZBTB43,SYN2,KIAA1107,TBCEL,TCF4,SSBP2,OSBP2,KCNAB1" Drug 5388_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "APLP1,APOC1,ARHGDIG,ATP6V0A1,CA12,PLEKHB1,B4GALT6,TAOK2,SH2B1,PDE4DIP,DZIP3,DBN1,LYPD1,DTNA,CNNM1,ZNF589,IQCG,TPK1,GCNT2,RUNDC3A,GLYR1,GPER1,ATXN2L,KCNH2,MBD1,TM6SF1,NF1,RETREG1,ZNF821,SH3BP2,ST5,CABIN1,HIRA,PLPPR2,KCNK12,ZNF24,EMSY,HPS4,KAT6A" Drug 5307_DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG3,EP400,EIF4G3,BCL7A,CFLAR,NFS1,DZIP3,ZNF337,PHF20L1,SUGP2,APH1A,F8,STRADA,FAM49B,MSL3,GPR37,DIDO1,CIT,MEIS2,MITF,N6AMT1,NACA,NF1,RETREG1,PLEC,RAD51D,SH3BGR,CCDC92,SMARCC2,MAPKBP1,DOP1A,DBNDD2,LHPP,SS18,NSFL1C,PARD3,HIRA,MPPE1,KAT6A" Drug 7452_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG2,AK2,SEMA6A,LTBP4,APOC1,SEMA4G,CDK13,KIF1A,SCAPER,SGCE,CNTFR,HS3ST2,VPS13B,MTSS1L,DLC1,KAT8,FGFR1,PRELID3A,OGA,ALDH1L1,GRM8,ITGA7,MAP2,MGAT3,MPP2,PPP2R2B,PRPH,RGS12,CLIP1,SLC2A5,SPTAN1,ATP10B,ST5,WSCD1,KIAA0930,TNS2,CDK20,GDPD5,KAT6A" Drug 6191_DN troglitazone; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG3,ADD2,AGT,FAM131A,KIF1A,BMP7,LDLRAD4,CARS,HIP1R,ENTPD6,TAOK2,PLAA,OSBPL3,CTH,DTNA,ING4,EIF1,PIPOX,GAA,CRCP,POLL,MAP4,ZNF862,SLC11A2,SLC25A23,PTN,RAD51D,ZCWPW1,ZDHHC14,ZNF821,MRAS,SUPT20H,FUZ,PPP4R3A,MAPKBP1,ZBTB43,TSPYL2,TRPS1,XRCC4" Drug 2156_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABR,NDRG3,NDRG2,APBB2,N4BP2L1,RIPK1,BACH1,SPAG9,CNOT8,DGKG,RCAN1,EPB41L2,RASGRP2,ZNF589,PDLIM5,TRAF3IP2,HMGCR,HSF2,KPNA5,LSS,NF1,NFYA,OCRL,ENPP2,CCSER2,MINDY2,RASA3,SLC2A5,SLC11A1,KDM4B,TROVE2,NXT2,NSFL1C,DNMBP,TBL1X,TCF4,ZEB1,THRA,ST7" Drug 7449_UP Risperidone [106266-06-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "AP2A2,BEGAIN,BIN1,CDC42BPA,NRP2,GYG2,ARHGEF10,CNTNAP2,RIMS2,EIF4G2,ZNF589,FGFR1,EFCAB2,FYN,SIGLEC8,RAB30,TDRKH,RNFT2,KCNJ5,MAP4,MEF2C,MIA2,AFF1,MMP16,LYRM9,NNAT,PRKCB,MAPK12,SH3BP2,SLA,SLC2A5,SPTAN1,ELOVL4,SMG6,PCDHA5,TNS1,FAM155A,VSNL1,KCNK12" Drug 4611_DN Tyloxapol [25301-02-4]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ARRB2,ADGRB2,LDLRAD4,TAOK2,SLC4A8,BAG4,TM9SF4,MFAP3L,KIAA0753,SLC12A6,RCAN1,RRAGB,ST3GAL6,FGFR1,ANKFY1,CINP,TRAF3IP2,GAD1,COPS8,CACFD1,MX1,PALM,PLXNB1,MAPK7,WDR25,FRMPD1,KBTBD4,SMARCD3,ZNF415,TMCC1,VPS13A,EXOC7,SMG6,KIAA0930,RIMBP2,OSBP2,TFIP11,EVI5,HPS4" Drug 3091_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABR,ABHD6,BIN1,ANK2,APBA2,DNAH17,CHN2,TAOK2,ABI3BP,C2CD2,SPOCK3,RASGRP2,MTSS1L,FGFR1,ZNF44,MGAT3,AFDN,MYO6,SLC11A2,NTRK3,NLE1,RELN,BCAS3,TMEM104,WDR25,ZSCAN32,PTPRN2,PID1,RGS12,PLPPR3,NLGN1,SLC11A1,UNC5B,ZC3H13,OBSL1,UBE3A,CLIP2,SH3GLB2,KCNAB1" Drug 2566_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "NDRG2,MTUS1,APBB2,ATP6V0A1,ST3GAL5,SGCE,HIP1R,SLC16A4,CLGN,CRLF1,SOCS6,PDE4DIP,SLITRK5,DZIP3,DOCK4,GSDME,RCAN1,FAM13A,TNK2,NCALD,RRAGB,PTK2B,FHL1,LYVE1,GSN,PADI2,ITGAM,NRCAM,PLCD1,POU6F1,PPP5C,KCTD17,PPM1E,SPTB,RGL1,PHLDB1,STXBP1,DNMBP,TPM1" Drug 2517_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ADCY6,SEMA6A,BBOX1,SEMA4G,ATP2B2,ADGRB2,CACNA1G,CACNB4,CAMK2B,AKAP5,HAPLN1,CNTNAP2,BRINP1,EDNRB,EPB41,EPHB1,FLT1,AFF2,LYVE1,TOX3,GNAL,KCNJ5,KCNN1,LAMA2,MEF2C,NEFM,RASGRF1,SEC14L1,CNKSR2,ST8SIA1,EPN2,KANSL3,LIMCH1,SNAP25,SPTAN1,SSTR2,TRIM2,CRTC1,JPH3" Drug 4771_UP Probenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-04 1.00E+00 3.34E-03 3.76E-02 39 195 "ABHD6,ALK,BEGAIN,AMPD3,SLC4A4,ARHGEF2,RAB33A,HAPLN1,CRY2,FCF1,ZNF589,ALDH1L1,LYVE1,GPER1,MMP16,MPP2,MSR1,NF1,PLCD1,PURG,PRKCB,C1orf54,EMID1,ZNF821,PREX2,SLC2A5,PKNOX2,SLC8A1,SLC11A1,COA1,SNCA,DOK5,PEG10,OBSL1,CRTC1,TK2,TRIO,VIPR2,ST7" Drug CID000003800 NSC613009 Stitch 3.03E-04 1.00E+00 3.35E-03 3.77E-02 29 131 "MYH7B,ARHGDIA,C5,CBS,CFL2,CLTC,CABP1,MYRIP,DCTN1,PTK2B,FCGR3A,FER,GALC,GSN,MYLK2,SCIN,ITGAM,ITPKB,MAP4,MYO5A,MYO7A,PIK3R1,PTH1R,PTK2,RYR3,SLC12A2,SLC14A1,ARC,ACTR6" Drug CID000123756 mantATP Stitch 3.04E-04 1.00E+00 3.36E-03 3.78E-02 12 35 "MYH7B,APAF1,DNAH9,CASP8AP2,DDX19B,KIFC3,MYO5A,PFKFB2,PFKFB3,PFKFB4,ABCB1,GSTCD" Drug 6879_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.05E-04 1.00E+00 3.37E-03 3.80E-02 37 182 "ASPHD1,ST3GAL5,BAIAP3,USP2,CLGN,WHRN,DOCK4,ARMCX2,JAKMIP2,OPTN,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MPP2,MXI1,NEK1,PCDH9,SERPINI1,PRPH,RPS6KA2,SH3GL3,WDR47,PKNOX2,SOX15,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,GDPD5,SLC17A7,ITM2C" Drug CID000073212 lead compounds Stitch 3.10E-04 1.00E+00 3.42E-03 3.86E-02 32 150 "ADCY5,ADCY6,ADCY8,ATP2A2,CACNA1I,CACNA1G,C5,CACNA1A,CALM1,PLCXD3,DTNA,EDNRA,ERCC2,FECH,AFF2,CRCP,PLCD4,GRIN2C,GRIN2D,HBA1,NOVA2,SLC11A2,PLCB2,PLCD1,PPP3CC,PRKCB,PTX3,RYR3,COPZ1,SLC11A1,PLCB1,FXR1" Drug CID000024572 lead arsenate Stitch 3.13E-04 1.00E+00 3.45E-03 3.89E-02 22 89 "ACHE,APLP1,APOC1,BCHE,RUNX1T1,NOG,CNR1,DMD,DTNA,DTNB,PDLIM5,HBA1,IL6ST,ZNF331,SNRPN,DDN,SYP,TPM1,TPM2,ZIC1,HPS4,NETO1" Drug 835_UP carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.22E-04 1.00E+00 3.54E-03 3.99E-02 38 189 "AMPD3,CDC42BPA,APLP1,CAMK2B,SLC16A4,SCARB1,CRLF1,TPP1,CNTFR,FAM149A,PDE4DIP,BRINP1,TOM1,IQCG,MAP4K5,IRAK3,RASSF8,ATXN2L,MGAT3,ADAM22,NPTX1,PCDH9,MINDY2,PPP1R1A,C1orf54,GTDC1,SH3BGR,FNDC3A,LIMCH1,PEG10,ZNF423,TSPYL2,CEP68,STX1A,TRIM2,DICER1,TRIO,EPM2A" Drug 4401_DN Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.22E-04 1.00E+00 3.54E-03 3.99E-02 38 189 "CDK13,EIF4G3,CFLAR,GYG2,SOCS6,TAOK2,SLIT2,RAB28,C2CD2,AKAP12,ZFYVE16,DTNA,EGFR,FGFR3,SYNCRIP,GAD1,USP19,MALT1,CNTRL,NF1,RETREG1,PLCD1,GRAMD1C,TTC17,LIMCH1,RBM34,SPART,CLASP2,KLHL7,TACC1,EXOC7,TMPO,BEX4,VGF,ZIC1,REEP1,EPM2A,ST7" Drug 4450_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 3.54E-03 3.99E-02 38 189 "PKP4,CDC14B,KSR1,LDLRAD4,HAP1,CACNA2D2,EPS15L1,CTH,GIT2,CDON,EDN1,SEMA3D,GLI2,GPD1,SYNPO,IL6ST,KCNF1,KCNH2,MMP16,NACA,NTRK3,OXTR,PDE1C,PDE4B,MBOAT7,PTN,ACSS3,CCDC40,RGS4,TCP11L1,HSPA4L,CNKSR2,PDZD2,ZC3H13,SYT1,TBL1X,TCF4,CDK20" Drug 2797_DN Seneciphylline [480-81-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.22E-04 1.00E+00 3.54E-03 3.99E-02 38 189 "AP2A2,APC,APOC1,STX16,CFLAR,SPAG9,CCNT1,EPS15L1,QKI,AKAP7,ENTPD4,CSNK1E,SOCS5,TBC1D5,DAPK3,LYPD1,EDNRA,FCF1,EPB41L2,PDLIM5,ARFIP1,GLYR1,RAB30,HTATSF1,MAP4K5,HSF2,ELOVL2,FBXO11,BTBD7,SEPT8,KANK1,PLCB1,FBXW11,TMPO,CDK20,ZNF24,GDPD5,PHTF2" Drug 7047_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "ADRB2,ARNTL,MARK4,ST3GAL5,ABCG1,PDE4DIP,CTH,PLPPR4,FAM13A,EPB41L2,TBC1D16,TAOK3,BAIAP2,PDLIM5,PCDH17,STON1,GUCY1B1,ITGA7,MAP2,MMP16,PCDH9,SERPINI1,RETREG1,PRPH,ENOX1,RBBP6,RGS4,RPS6KA2,SH3GL3,ASAP3,ARHGAP26,THSD1,RGL1,SYT1,PLPPR2,TRIM9" Drug 1345_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "ADRB2,ARNTL,CDK13,ZBTB10,SLC4A4,RIPK1,CNOT8,TPP1,ZFYVE16,DBN1,DTNA,FAM13A,ENO2,ANKFY1,ARFIP1,GLUL,ITGAM,LIG4,MXI1,PFKFB3,POLG,MINDY2,RET,SUPT20H,FBXO11,SLC2A5,SLC6A8,KDM4B,KDM3A,KDM4C,NXT2,TLR4,KAT6B,TNS1,REEP1,TFIP11" Drug 2666_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "CLK4,MTUS1,AMPD3,APAF1,DNAH17,CDO1,CREM,CRY2,PDE4DIP,ZNF337,DGKG,HIPK3,FAM13A,MBNL2,EIF5,BAIAP2,PRKAG2,OGA,GCNT2,LILRA2,STON1,NINJ2,PDE4B,PLCD1,PMP22,MBOAT7,PRKACB,HSPA4L,TMCC1,SPTAN1,DNMBP,RPGRIP1L,TPM1,ZBTB38,UBE3B,FXR1" Drug 6886_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "AK2,ARNTL,CACNA1I,USP2,ENTPD4,VCAN,PDE4DIP,CTH,DAPK3,DBT,FCF1,TUBD1,EPB41L2,TAOK3,BAIAP2,PDLIM5,CYP46A1,GUCY1B1,ACOT7,LSS,MAP2,MAPT,MMP16,SERPINI1,MINDY2,RGS4,ASAP3,COA1,SOX15,SS18,RGL1,SYT1,HIRA,UBE2H,SH3GLB2,SLC17A7" Drug 1393_UP Nocodazole [31430-18-9]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "ARRB2,MARK4,CFLAR,KRIT1,CD86,FOXN3,CHN2,CREM,PPP1R16B,DOCK4,PDLIM5,MALT1,MEF2C,PDE4B,PDE4D,SMOX,SMIM7,LRP12,MINDY2,PPM1B,PRKACB,PTK2,PTX3,CLIP1,ATXN7,SGK1,MAPKBP1,SAMSN1,STX1A,PLCB1,TACC1,ANKRD12,FLRT2,WIPF1,CLDND1,EVI5" Drug 2485_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.23E-04 1.00E+00 3.56E-03 4.00E-02 36 176 "MTUS1,C1QTNF1,BIN1,FAM131A,DNAH17,ATP2B2,CFLAR,CD86,CBFA2T2,CD38,CHN2,CHRNA4,COL9A3,CREM,CRMP1,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,SHANK1,DTNB,HIPK3,FAM13A,BAIAP2,AGAP2,KCNQ3,NINJ2,PDE4B,PDE4D,PID1,SGK1,SPTAN1,TACR1,ZFPM2,LMF1,PRDM10" Drug DB00277 Theophylline Drug Bank 3.24E-04 1.00E+00 3.57E-03 4.02E-02 5 7 "ADORA1,ADORA2A,PDE3A,PDE4A,PDE4B" Drug CID000197303 Be 18257b Stitch 3.24E-04 1.00E+00 3.57E-03 4.02E-02 5 7 "EDN1,EDN3,EDNRA,EDNRB,IGF1" Drug CID000119072 vioxanthin Stitch 3.24E-04 1.00E+00 3.57E-03 4.02E-02 5 7 "CD86,MAPK3,MAPK9,MAPK10,GORASP1" Drug ctd:C005238 mipafox CTD 3.24E-04 1.00E+00 3.57E-03 4.02E-02 5 7 "ACHE,BCHE,NEFH,SYN1,SYP" Drug 7182_UP Strophanthidin [66-28-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADCY6,AK2,PPFIA3,ADAM15,BCL7A,CFLAR,BMP7,SYNJ2,RAB29,RAB28,RASSF2,JAKMIP2,LYPD1,RCAN1,COQ7,PRKAG2,SEMA4D,EFCAB2,COPS8,ELOVL5,HNMT,JAK2,KCNH2,LIG4,RETREG1,MINDY2,PRODH,RIPOR1,RGS12,KCNIP1,PPP4R3A,RBM34,TROVE2,SS18,ARC,PCDHA6,AP4E1,ZBTB14,UBE3B" Drug 1978_UP Prednisone [53-03-2]; Up 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "SPOP,KRIT1,SRSF11,FBXL5,KCTD3,EPB41L2,STX2,FKTN,SEC23B,EFCAB2,ATP2C1,HTATSF1,IRAK3,HSF2,KTN1,LAMP2,MARK3,NINJ2,NTRK3,NUCB2,RETREG1,PPM1B,ATXN7,CHD9,KBTBD4,UNC5B,IQSEC2,SPART,SS18,NSFL1C,KLHL7,SYN2,TCF4,DMXL2,NPL,HIRA,UBE2H,EVI5,HPS4" Drug 3049_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "SPARCL1,SLC4A4,MPDZ,DLGAP1,PLEKHB1,ABCG2,COL9A3,SEC14L5,AASS,SRPK3,VPS13B,REEP2,FGFR1,FGFR3,SIGLEC8,RUNDC3A,PCLO,SOX21,GUCY1A1,RASSF8,SCIN,KCNN1,LSAMP,ADAM22,PLXNB1,NECAB2,PPARA,PPP1R1A,PTH1R,CCDC40,RGS4,NUDT11,SCN8A,ZSWIM8,IZUMO4,PEG10,TIAM1,KLC2,KCNK12" Drug 3837_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABR,ASIC1,NME5,ADGRF5,SEMA7A,PLA2G4C,CDK13,STOML1,PICK1,COL9A3,NCOR2,CNTNAP2,DAPK3,RUSC2,SGSM2,EIF4G1,TNK2,CALCRL,ERCC2,DLC1,FGF13,RUNDC3A,GSN,DHX35,KCNH2,KHK,LSS,MMP17,PRKCB,ZNF331,RASA3,HECW1,IQSEC2,TBCEL,WSCD1,TRIO,FLRT2,SPHK2,AP3B2" Drug 3025_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADCY6,SPARCL1,ANK2,CACNA1G,CACNB4,THSD7A,ARHGAP33,CHN2,NRXN3,FAM149A,WHRN,COL9A3,HEYL,AASS,SRPK3,EPB41,CORO2B,DENND2A,SIGLEC8,ALDH1L1,RUNDC3A,GPR37,HNMT,MATN2,NPY,NTRK3,SEPT4,PPP1R1A,PTPRN2,RGS4,MAP6D1,ATP10B,ARC,SYT1,PHF24,TRIO,TRO,WNT7A,KCNK12" Drug 5060_DN Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "EPB41L5,CDK10,SLC4A4,SOCS6,PLEKHB1,TPP1,QKI,HAPLN1,CSF1R,EXOG,RCAN1,MBNL2,STX2,CDKL3,ETV1,TDRKH,GPER1,CNTRL,MPP2,NF1,PLCD1,FA2H,PPARA,CNNM2,ZSCAN2,BEND5,GAL3ST4,MAPK12,SBF1,CSRNP3,SCN8A,DZIP1,PEX26,SLC14A1,THSD1,DNMBP,GPR161,SSBP2,ZNF45" Drug 5084_UP Resveratrol [501-36-0]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADCY6,KCNAB2,GAS7,RASL11B,MYRF,CHN2,ARHGAP22,AKAP5,CRY2,ABCG1,CSF1,PDE4DIP,RUSC2,EDNRA,FGF1,ADAM28,GPER1,TPPP,ICA1,SHISAL1,MAPT,MMP17,MYO7A,SERPINI1,RETREG1,PLCD1,PTPRH,PTPRN2,TMEM231,RPS6KA2,AMBRA1,ARHGEF40,SAMSN1,TIMP4,R3HDM1,TNS1,NDRG4,SPHK2,GAN" Drug 7377_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "C1QTNF1,APBB2,CDK10,SYNJ2,MYRF,RAB28,ENTPD4,B3GAT3,SGSM2,CDON,F8,POMT1,GAD1,B4GALNT1,DISC1,CRCP,SYNPO,MYO9A,ZNF862,NFIX,NPR2,SLC11A2,PCDH9,SERPINI1,POLG,FSD1,PTN,RIPOR1,RPS6KA2,FAM102A,FAM214B,LIMCH1,ARHGAP26,SYNE1,CABIN1,VGF,ZBTB14,MAP3K12,NT5M" Drug 4389_DN Sulpiride [15676-16-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADORA2A,SEMA6A,LTBP4,AMT,APC,APLP1,CFLAR,MTMR3,CACNA1I,ARHGEF2,RIMS2,PPP6R2,RUSC2,HIPK3,HSD17B14,FGFR1,PRELID3A,SRCAP,AHDC1,PRRC2B,ICA1,TJAP1,CNOT4,NTRK2,LRP12,PRKAR1B,ZSCAN32,ZSCAN2,TMEM231,KCNIP1,SH3BP2,ASAP3,KDM4B,PHLDB1,WSCD1,ZKSCAN5,HIRA,EMSY,MPPE1" Drug 2740_DN Pyrithyldione [77-04-3]; Down 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABHD6,MTUS1,FUBP1,HIP1R,FOXN3,QKI,CLOCK,PDE4DIP,RUBCN,DGKG,CNNM1,EGR3,ING4,TUBD1,PTK2B,FHL1,TRMO,PDLIM5,INPP5K,COPS8,LILRA2,PADI2,ATXN2L,ITGAM,MAP4,PIK3R1,CCSER2,NLE1,SLC25A23,MINDY2,ZNF821,CCDC88A,ZKSCAN3,PLCB1,KIAA1107,CRTC1,ZNF34,TRPS1,ZNF225" Drug 403_UP alpha-estradiol; Up 200; 0.01uM; ssMCF7; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,ADD2,ADORA2A,KCNAB2,BCAS1,AQP6,RASL11B,HAP1,CD86,CD38,PCYT1B,CSNK1E,CYBB,CHRDL1,RCAN1,EYA1,FOLR2,ALDH1L1,CYP46A1,PTPRT,IGF1,KCNJ5,KCNQ3,SLC11A2,NTRK3,PDE4D,PLXNB1,PTPRN,RGS4,RNH1,ABLIM3,LIMS2,ZKSCAN3,NMNAT2,SPTB,LMO3,SSTR2,TRIM2,TRPM2" Drug 3342_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,CDC42BPA,APBA2,PPFIA3,MARK4,CFLAR,SCAPER,GYG2,CREM,CRY2,CSNK1E,SIPA1L1,MAML1,DAPK3,PARD6A,DTNA,STX2,FER,BAIAP2,PDLIM5,TXNL4A,GNG4,STON1,KCNJ5,LSS,NPTX1,WDR25,ZDHHC14,SYBU,KIF13A,CDK19,ELOVL4,VPS13A,EXOC7,SMG6,AP4E1,TRIO,REEP1,EVI5" Drug 4420_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "SYN3,ADCY6,ADRA1D,LTBP4,GAS7,CDC14B,RASL11B,ADAM23,AZGP1,BAIAP3,LDLRAD4,CHRNA4,RGS6,BRINP1,EDN3,MBNL2,TNK2,F5,FHL1,ZNF44,IRF8,MYCN,NEFM,NF1,PDE1C,GPR85,PLXNB1,KHDRBS2,KLHDC8A,LIMS2,PKNOX2,SNCA,HECW1,SPTB,PLCB1,TRPM2,WIPF1,SLC30A3,DPF3" Drug 5322_UP Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADRA1D,TRMT9B,AMH,AMPH,APBB2,APOC1,PPFIA3,ARHGDIG,C5,HAP1,TAOK2,PICK1,EGFR,MBNL2,RGS17,ANKMY1,F5,DLC1,SEPT9,GLYR1,POLL,CACFD1,MAP4,MPP2,MSI1,ADAM22,LYRM9,NF1,RETREG1,PPP2R2B,MAPK7,FAM184A,SYBU,STX1A,EXOC7,CABIN1,TRPM2,VAV1,SEMA3B" Drug 2707_UP Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,BIN1,DNAH17,MARK4,PTCH2,SGCE,CFAP410,CACNA2D1,THSD7A,CREM,CRY2,NCOR2,ABCG1,RIMS2,ANKMY1,FGFR1,FOXF2,GFER,PCDH17,GUCY1A1,MBNL1,NF1,CNOT4,NOVA1,NPTX2,PAX6,PLCL1,CEP41,VPS13C,PID1,SUSD4,LIMCH1,DNMBP,DNAH7,HEY1,RUNDC3B,ZBTB38,SLC17A7,KCNAB1" Drug 5073_DN Loracarbef [121961-22-6]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "RALGAPA1,ADCY6,AP2A2,APC,APOC1,FOXN3,SOCS6,B4GALT6,TPP1,AKAP7,BAG4,CSF1R,VCAN,ARHGAP24,SEMA4D,IFI16,MX1,ZNF862,NDP,CLDN11,PLCD1,MAPK7,CNNM2,PTPN13,PTPRE,FAT4,TRAPPC13,MAPK12,SCN8A,SH3BP2,FUZ,COA1,SPTAN1,ZNF34,TNS1,WNT7A,FIP1L1,KAT6A,PHTF2" Drug 1642_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABHD6,AK2,BEGAIN,CDC42BPA,ARHGDIG,MARK4,SLC4A4,SCAPER,BAIAP3,LDLRAD4,HAP1,SLIT2,EPS15L1,SULT4A1,HOMER3,LYPD1,DMPK,RCAN1,DTNA,HIPK3,CNNM1,MBNL2,FHL1,GCNT2,MSL3,HSF2,IRF8,MIA2,LRP12,WDR25,TCP11L1,EMID1,FNDC3A,KDM4C,STX1A,ZNF34,WIPF1,HPS4,KCNAB1" Drug 6028_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ASIC1,C1QTNF3,CDC14B,CACNA1I,CA4,ARHGEF1,ARHGEF2,SEPT7,TAOK2,RCHY1,ENTPD4,CRMP1,CSF1,SIPA1L1,DCAF4,MAML1,ING4,ZNF589,FYB1,POLL,ELOVL5,INPP5B,KCNF1,KCNH2,MSI1,PLEC,STRN3,PRKAR1B,PRODH,CEP97,SEMA6D,VPS13A,DICER1,TK2,PARD3,SSBP2,VGF,KCNK12,KCNAB1" Drug 2063_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "PKP4,CASK,CDK13,SCAPER,RAB29,MYRF,KRIT1,CLCN3,HOMER3,LYPD1,DPH1,FCF1,COQ7,FGF1,TRMO,IL6ST,MAPT,MEF2C,SCAMP5,ADAM22,NFYA,PTPRE,ZDHHC14,RGS4,KIRREL1,TRA2B,PPP4R3A,IFT122,IQSEC2,CDK19,SAMSN1,EXOC7,TBCEL,TCF4,KIAA0930,UGT8,ZNF189,MAP3K12,KAT6A" Drug 5723_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "MTUS1,APLP1,ATP2A2,ALDH7A1,ARHGEF2,ASIC3,SULT4A1,VCAN,TOM1,STX2,ANKMY1,EZH1,FGF13,OGA,FYN,GNG4,GPER1,MAPT,MBD1,SCAMP5,ADAM22,ZNF862,NDP,NF1,CNOT4,NPR2,RETREG1,PID1,GAL3ST4,FAM102A,AMBRA1,FBXO11,CCDC88A,SLC22A4,TROVE2,ZNF34,METTL3,VGF,PHTF2" Drug 1267_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "C1QTNF3,BBOX1,CDK10,CAPN3,SLC16A4,IQCK,ARMC8,RNF14,DTNA,COQ7,MTSS1L,ST3GAL6,EFCAB2,CINP,CGREF1,ZNF44,LYVE1,KCNMB4,LILRA2,LPAR4,PADI2,DHX35,LSS,NINJ2,RELN,BCAS3,PTCH1,RET,SEC14L1,LIMS2,PKNOX2,SLC12A2,PLCB1,KIAA1107,SIN3B,CHST8,TNS1,CDK20,TFIP11" Drug 5294_DN Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "OSBPL1A,NCOA1,CAMK2G,SCARB1,ENTPD6,LRRFIP1,CHN1,NCOR1,FAM169A,CTH,ARHGAP32,LYPD1,RHOBTB1,DNM1,FGFR3,ANKFY1,CINP,FAM49B,ATP2C1,ERAP1,INPP5K,COPS8,ZNF638,INPP5B,AFF1,SLC11A2,OPA1,PCDH9,STRN3,PKIA,VPS13C,RCOR3,MAPKBP1,SOX3,ZSWIM8,CEP68,SYT1,TACC1,PRDM10" Drug 667_UP 6-mercaptopurine monohydrate; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABHD6,BIN1,N4BP2L1,NRP2,BMP7,ST3GAL5,RAB29,SEPT7,TMEM184B,RAB26,CNTN1,CRYM,MBNL2,ATP2C1,RUNDC3A,CNTRL,PADI2,KHK,TAGLN3,NOVA2,GPR173,PTH1R,QDPR,RGS3,RNASE1,KLHDC8A,GSTCD,SLC2A5,KBTBD4,SNCA,SPART,LMO3,ATP10B,CAMTA2,ZC4H2,PHF24,SIRT1,TNS1,TFIP11" Drug 4667_DN Azathioprine [446-86-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADRA1D,MTUS1,NME5,PPFIA4,PPFIA3,SLC4A4,LDLRAD4,SCARB1,ARHGEF2,AKAP7,NRG2,VCAN,PDE4DIP,BRINP1,RUSC2,EDNRA,FGFR1,SCARA3,MAPT,MITF,NF1,PDE4D,PIK3R1,SLC25A23,STRN3,TMEM231,KHDRBS2,RGS4,ZFP30,FRMPD1,SLC4A3,EPN2,ARHGAP26,TCF4,AP4E1,TK2,AMACR,WIPF1,KCNAB1" Drug 4283_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AMPD3,ZSCAN18,BMPR1B,BAIAP3,CAMK2B,CLDN10,TPP1,STOML1,HOMER3,DAPK3,SGSM2,DMPK,EDN1,HIPK3,ANKFY1,ZNF44,USP19,RUNDC3A,GPR12,KIT,LSS,MAPT,PLEC,POLR2F,ELOVL2,ZMAT4,RGS4,ZFP2,SH3BP2,DZIP1,SLC12A4,SMARCA4,PLCB1,SZT2,TK2,FLRT2,LAT2,SH3GLB2,DPF3" Drug 7127_DN Monocrotaline [315-22-0]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABR,BRAP,APBB2,APLP1,CDK10,CFLAR,B4GALT6,USP6NL,RCAN1,SUGP2,EGFR,EIF5,STX2,SCML2,FGFR1,GPD2,DIDO1,GUCY1B1,FAM69A,MBNL1,MPP2,KCTD15,PPP3CC,RIPOR1,RAD51D,SUGCT,MCMBP,ANKRD6,LIMCH1,ZBTB43,PBLD,DIP2A,ARHGEF9,VPS13A,HIRA,FAM155A,LMF1,XRCC4,HPS4" Drug 3208_DN Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "APBB2,CDC14B,KRIT1,B4GALT6,RAB28,HOMER3,CSNK1E,DBT,PARD6A,ING4,ENO2,FGFR1,BAIAP2,SRCAP,GNG4,FERMT2,GRB10,BTN2A1,HNMT,HSF2,MIA2,NEK1,PCDH9,VPS13C,NKAIN1,RAP1GDS1,NEK11,TRAPPC13,COA1,TSPYL2,TROVE2,POGZ,TMPO,HIRA,UBTF,LMF1,XRCC4,HPS4,PHTF2" Drug 3401_UP Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NME5,BIN1,RASL11B,MTMR3,LDLRAD4,CACNA2D1,HIP1R,PLEKHB1,TPP1,AKAP5,NECTIN3,VCAN,RASSF2,TMCC2,MBNL2,FHL1,PCDH17,GPER1,GRB10,GSN,ICA1,TJAP1,LIFR,LSS,MX1,NELL2,TMOD2,SLC9A5,HECW1,SPTB,LMO3,JMJD6,SYN2,FAM189A1,LAT2,EPM2A,PHTF2,ADAMTSL3,SENP7" Drug 7102_UP 0198306-0000 [212631-61-3]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ASIC1,APBB2,APLP1,APOC1,MARK4,SYNJ2,CDH2,CSF1,CSNK1E,PDE4DIP,SLITRK5,RIPOR2,FEM1B,ING4,FGF1,SEMA4D,CSPG5,GAD1,GPER1,BACH2,HMGCL,KIFC3,LYRM9,ZNF862,NPR2,POLG,CNNM2,PTCH1,BEND5,SUGCT,SH3BP2,LIMS2,FAM214B,IQCE,TCF4,AP4E1,TK2,LMF1,MAP3K12" Drug 4472_DN Estropipate [7280-37-7]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "APOC1,SEMA4G,ARRB2,PDE8B,SYNJ2,SYNGR3,CACNA2D2,HAPLN1,AATK,CSF1R,VCAN,SNPH,PLXNC1,ING4,STX2,CINP,FYB1,SYT17,STON1,LSS,MPP2,NFIX,NPR2,PPP5C,RAD51D,ZCWPW1,GAL3ST4,KIRREL1,NEK11,RPS6KA2,SLC9A5,BTBD7,DDN,RPGRIP1L,CRTC1,BHLHB9,R3HDM1,ZNF24,TIGD6" Drug 2310_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NME5,KIAA1324,BEGAIN,BIN1,CDC42BPA,ARSE,RASL11B,CFLAR,KALRN,SULT4A1,CNTFR,NRG2,ARHGEF10,KLHL3,EDIL3,HIPK3,LRRC17,RASGRP2,ERCC2,SPEG,F5,ZNF589,AGAP2,DISC1,NXPH3,ITGAM,LIG4,NNAT,NPTX1,OGG1,PDE4B,SLC9A5,ATP10B,WSCD1,SLC35G2,TRO,LAT2,SLC30A3,ST7" Drug 2628_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "MTUS1,CDC42BPA,EPB41L5,BCAS1,ADAM15,ST3GAL5,FUBP1,SPAG9,CLCN3,FAM189A2,CREM,SIPA1L1,FBXL5,EIF5,TNK2,EXTL2,ANKFY1,CGREF1,SRCAP,MSL3,LIG4,NF1,SLC11A2,TMEM231,ZDHHC14,CLIP1,AMBRA1,SS18,NXT2,DIP2A,PHLDB1,ASTN2,EXOC7,TBL1X,TIAM1,TMPO,UBTF,XRCC4,RNF146" Drug 1604_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; HL60; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "MARK4,EIF4G3,RAB28,CLCN3,PPP1R16B,PPP6R2,RUBCN,ARHGAP32,DCAF8,GIT2,FEM1B,CELSR3,ENO2,STX2,SEC23B,SMC2,ATP2C1,OGA,IFI16,LAMP2,PLCD1,PLEC,MAPK3,SAMD9,PTX3,RPS6KA2,ATXN7,ELMO2,KDM4B,GLT8D1,CDK19,THSD1,KLHL7,NR2C2,HIRA,WIPF1,HPS4,RNF170,AAAS" Drug 363_UP sodium 4-phenylbutyrate; Up 200; 100uM; HL60; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,OGT,NCOA1,ATP6V0A1,CBFA2T2,ARHGAP33,CLTB,SULT4A1,RAB26,C2CD2,ARHGEF4,RIMS2,MAML1,BRINP1,ING4,STX2,FGFR1,OGA,RUNDC3A,BTN2A1,SOX21,ICA1,FXYD7,NFYA,PLCB2,PLEC,C1orf109,RIPOR1,RGS12,KLHDC8A,MAP6D1,KDM4B,ZSWIM8,ZC3H13,SPART,SS18,HIF3A,PLPPR2,SLC17A7" Drug 6994_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,CDC42BPA,NCOA1,CFLAR,ST3GAL5,CBFA2T2,ZMYM4,PLAA,MAP4K4,AKAP12,SOCS5,INTS1,FBXL5,EPB41L2,VPS26C,PRKAG2,POMT1,CAMKK2,B4GALNT1,ZNF276,TXNL4A,FERMT2,KCNF1,NCAM2,NEK1,STRN3,RIPOR1,RGS3,NEK11,SBF1,SH3BP2,RCOR3,USP33,EXOC7,BHLHB9,SSBP2,UBTF,ZNF24,URM1" Drug 5345_UP Midecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,SEMA7A,APOC1,ARRB2,BCL7A,ST3GAL5,SYNJ2,BAIAP3,QKI,DTNA,FEM1B,NCALD,F5,ZNF589,ZNF276,GLYR1,GRIK5,BTN2A1,TJAP1,INPP5B,LIG4,LSS,MATK,MEIS1,NEK11,TCP11L1,FNDC3A,ZHX3,UNC5B,ZBTB43,PLCB1,SLC44A1,TK2,UBE2H,NT5M,HPS4,KCNAB1,ST7,UBE3B" Drug 2775_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADCY6,CDC42BPA,GYG2,CAMK2G,CNOT8,SLIT2,CLCN3,CRY2,PDE4DIP,PARD6A,DTNA,FGFR1,ANKFY1,ALDH1L1,TXNL4A,MSL3,GPD2,BTN2A1,ITPKB,MAN2A2,ZNF862,CNOT4,STRN3,MAPK7,SBF1,ASAP3,SLC6A8,LIMCH1,MAPKBP1,CDK19,ST5,STX1A,ASTN2,ANKRD12,RPGRIP1L,PCDHA6,PARD3,VLDLR,REEP1" Drug 4779_DN Pyrimethamine [58-14-0]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "BIN1,PPFIA3,ADAM15,CFLAR,CAMK2G,LHX2,HOMER3,SH2B1,CSNK1E,DCTN1,ZNF804A,SGSM2,DTNA,EIF5,PDLIM5,FAM49B,KHDRBS3,SEPT9,ZNF276,ELOVL5,HNMT,MAP4,MITF,PDE4A,PLXNB1,SAMD9,RGS3,KCTD17,EPN2,ELMO2,BTBD7,KIF13A,CEP68,ARHGEF9,MCF2L,NSD1,TMEM121,CABIN1,HPS4" Drug 2724_UP Amrinone [60719-84-8]; Up 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,APC,EPB41L5,PRX,CACNA1G,CACNA2D1,LARGE1,CHN1,FAM149A,SIPA1L1,CNTNAP2,INTS1,EDNRA,EGFR,ELN,C3orf18,TBC1D16,FHL1,PRELID3A,PCDH17,TJAP1,SCIN,FXYD7,NEFM,OXTR,PLCD1,PURG,PKIA,WDR25,PTPN13,RGS3,RPS20,ASAP3,PKNOX2,SNCA,ZSWIM8,ZFPM2,CHST8,RUNDC3B" Drug 2667_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADORA2A,TRMT9B,PPFIA4,APBB2,NUMB,BACH1,LDLRAD4,TPP1,IQCK,NCOR2,ARHGEF10,CSNK1E,CTH,ARHGAP32,ELN,CAMKK2,SEPT9,SPACA9,TJAP1,KPNA5,MAP4,MAPT,MGAT3,MYO6,NNAT,OGG1,PTK2,KHDRBS2,RPS6KA2,SCN2B,PPM1E,FRMPD1,DDN,SS18,RGL1,PLCB1,NSD1,VIPR2,TIGD6" Drug 5807_UP Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AGT,C1QTNF1,SYT13,ANK2,DNAH17,CFLAR,CACNA2D1,ABCG2,HAPLN1,SLITRK5,GIT2,EDN3,EGFR,MBNL2,IRAK4,TNK2,ELN,RRAGB,SCML2,BAIAP2,CGREF1,SPACA9,GSTM5,ICA1,KIF2A,MAN2A2,MAPT,NTRK2,ENPP2,PPP5C,FNDC3A,LIMS2,SLC11A1,IQSEC2,ARC,TRIM2,TLR4,TPM1,KCNAB1" Drug 5394_DN Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ALDH7A1,SYNJ2,PLAA,AKAP7,NECTIN3,PDE4DIP,DAPK3,FBXL5,ING4,ZNF589,FGFR1,GALC,GCNT2,GLYR1,GPER1,GRIK5,IPO5,MIA2,KITLG,ADAM22,NEK1,NF1,PDE4A,SLC25A23,LRP12,PRKAR1B,RGS12,MAPK12,SH3BP2,KIF13A,FNBP1,CLSTN2,PHLDB1,PLCB1,TK2,CABIN1,VLDLR,GDPD5,PHTF2" Drug 5338_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AMT,APC,RGS20,PDE8B,CFAP410,CHRNA4,C2CD2,DAPK3,GIT2,MFAP3L,RCAN1,KAT8,ZNF589,PRELID3A,GALC,SEPT9,POLL,KCNH2,LSS,MAN2A2,MAP4,MITF,MPP2,NEK1,NF1,NLE1,PLEC,LRP12,CEP97,RGS3,NEK11,RPS6KA2,CLSTN2,SS18,ADGRL3,PARD3,PLPPR2,GDPD5,MPPE1" Drug 6666_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AMPD3,KIF1A,ADAM23,ARHGEF1,CBFA2T2,SYNGR3,NRXN3,STOML1,QKI,VCAN,PDE4DIP,ARHGEF4,RIMS2,RUSC2,SPOCK3,PLXNC1,AASS,TENM1,MTSS1L,BAIAP2,DCTN2,CINP,GNAL,GNG4,GRM8,NOVA2,NLE1,PPP5C,SAMD9,PID1,ZCWPW1,DZIP1,ZNF667,IQSEC2,SAMSN1,TBCEL,GPR161,TIAM1,SEMA3B" Drug 1691_DN Triflupromazine hydrochloride [1098-60-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABHD6,AP2A2,AMPD2,APAF1,NCOA1,ST3GAL5,C5,CCNT1,TAOK2,CLOCK,ABCG1,GIT2,FEM1B,IRAK4,EZH1,FER,HSF2,IL6ST,IPO5,MAPT,MIA2,NFYA,CCSER2,SLC25A23,MINDY2,PRKAR1B,SNRK,TMEM231,ACSS3,FBXW7,CEP68,TACC1,RPRM,UBTF,WRN,TFIP11,EVI5,RNF170,LAS1L" Drug 4523_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "SYT13,TRMT9B,GAS7,CDK10,ZSCAN18,N4BP2L1,ADAM23,RGS11,CACNA1A,HIP1R,SLC16A4,CBFA2T2,SCARB1,CHRNA4,CNTNAP2,EGFR,EIF4G2,DLC1,FGFR1,FYB1,ZNF44,GLI2,GNG4,GPER1,MSR1,NF1,NOVA2,NRCAM,PDE4D,PPARA,ELOVL2,ZCWPW1,RFX2,CCDC102B,SLA,ZNF415,ZEB1,TIMP4,TPM2" Drug 3700_UP Merbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ARHGDIG,ATP1A3,N4BP2L1,BMP7,USP2,NRXN3,BRINP1,RASGRP2,MTSS1L,CORO2B,SEMA4D,ZNF44,GNAL,MCHR1,GRM8,C2orf72,KCNQ3,KIF5A,MEF2C,AFDN,MYH3,SLC11A2,PCDH9,MTRF1L,ZSCAN32,RASGRF1,RGS4,PKNOX2,SNCA,SYN2,ADGRL3,PCDHGA10,RIMBP2,TNS1,TPM1,TRIO,VIPR2,TFIP11,EPM2A" Drug 2621_DN Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ARNTL,STX16,CFLAR,BMP7,GYG2,CAMK2B,SOCS6,QKI,SIPA1L1,PDE4DIP,FCF1,SUGP2,EGFR,FER,AGAP2,NOP56,GPER1,GRIK5,RNFT2,HNMT,IPO5,MAPT,NCAM2,OGG1,WDR25,ELOVL2,CEP97,ZDHHC14,EMID1,ZNF821,SNCA,SOX3,NXT2,TMPO,CABIN1,CDK20,XRCC4,REEP1,RNF146" Drug 4773_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "CDC42BPA,APBB2,CDC14B,LDLRAD4,SCARB1,SLIT2,TPP1,CNTN1,WHRN,DAPK3,SPOCK2,EGFR,NRN1,ACSL4,FER,FGF1,FYB1,ALDH1L1,POLL,NXPH3,MPP2,ENPP2,PLTP,MAPK7,KHDRBS2,PBRM1,SH3GL3,FRMPD1,CNKSR2,LIMS2,IZUMO4,EXOC7,TAL1,WSCD1,HEY1,RIMBP2,CHST5,ZNF711,KCNAB1" Drug 6605_DN Lactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "RALGAPA1,BIN1,PDE8B,SLC4A4,CACNA1A,LARGE1,TPP1,AKAP7,WHRN,SGSM2,TOM1,TNK2,COQ7,ERCC2,ZNF549,POLR1B,FGFR1,ANKFY1,DENND2A,GAD1,HLF,HSF2,TJAP1,ADAM22,LYRM9,PRKAR1B,GRAMD1C,SAFB,SBF1,ZNF821,ZFP30,SLC4A3,TMCC1,CRTC1,CABIN1,RPRM,WIPF1,EMSY,EPM2A" Drug 3025_DN Acetaminophen [103-90-2]; Down 200; 26.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "RALGAPA1,C1QTNF3,AMT,MARK4,BACH1,SYNJ1,SLC16A4,ARHGAP33,CLGN,FOXN3,QKI,SLITRK5,F5,ZNF589,FER,PRKAG2,FHL1,AHDC1,LILRA2,SPACA9,MAN1B1,NCKAP1L,MID1,NINJ2,PPARA,NEK11,RASA3,SMARCC2,KDM4B,ZSWIM8,PDLIM2,DMXL2,KAT6B,SMUG1,SSBP2,REEP1,SH3GLB2,EMSY,PARP11" Drug 2280_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,ALK,RGS9,NRP2,SCAPER,CACNA1G,LDLRAD4,HAP1,CAMK2B,ASIC3,CPS1,CSF1R,MBNL2,IGSF6,DLC1,ZNF589,NEU3,HLF,C2orf72,ITGAM,KCNJ5,MAP4,MSR1,NF1,PLCB2,PRKAR1B,PTCH1,CRTAC1,TCP11L1,ZFP2,FNDC3A,FAIM2,SAMSN1,WSCD1,CHST8,SLC44A1,RIMBP2,NT5M,DPF3" Drug 7131_UP Ronidazole [7681-76-7]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "CFLAR,SCAPER,IL33,CBFA2T2,TPP1,PCYT1B,PDE4DIP,DZIP3,GPRASP1,LYPD1,CDON,OPTN,TNK2,ETV1,BAIAP2,COPS8,KCNMB4,GUCY1B1,RASSF8,BACH2,HSF2,INPP5B,KCNN1,MAPT,SCAMP5,MMP16,NPR2,MAPK7,PTPRE,PTPRH,MAPK12,PEX26,PPP4R3A,ZNF667,KDM4C,PHLDB1,ZFPM2,ZNF74,RNF170" Drug 3167_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ABHD6,ADCY6,LTBP4,TRMT9B,CDC42BPA,CDC14B,MARK4,CAMK2G,KYAT1,SRSF11,PLEKHB1,FAM189A2,HOMER3,AKAP7,BAG4,CRY2,PDE4DIP,GIT2,FGFR1,PRELID3A,ZNF44,USP19,POLL,GRB10,MUM1,HNMT,NF1,PLEC,EMID1,ZNF821,PEX26,KIF13A,ZSWIM8,CHST8,ZNF34,ZKSCAN5,HIRA,LMF1,UBE3B" Drug 3288_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ASPHD1,APOC1,SYNJ2,CFAP410,ARHGEF2,CACNA2D2,LHX2,EPS15L1,QKI,CSNK1E,DCTN1,RCAN1,TOM1,CELSR3,STX2,F8,BAIAP2,FAM49B,CGREF1,GPD2,GSN,MAP4,KITLG,GIT1,PDE4A,SLC25A23,PLXNB1,MBOAT7,MAPK7,MSANTD2,GSTCD,ZFP30,PDZRN3,CEP68,VPS13A,EXOC7,KIAA0930,MARCH8,RNF170" Drug 832_UP Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "KCNAB2,APBB2,SLC2A11,CFLAR,CACNA1G,CBFA2T2,SRSF11,COL9A3,RIMS2,SPOCK3,ZNF44,DISC1,SPACA9,GRM8,BTN2A1,KCNH2,ADAM22,PFKFB2,RETREG1,SAMD9,C1orf54,KHDRBS2,GTDC1,ROBO1,SCN2B,ZNF821,FRMPD1,FAM214B,BTBD7,TSPYL2,CLSTN2,DIP2A,TACC1,FAM208A,KIAA0930,SSBP2,TFIP11,ITM2C,EPM2A" Drug 2961_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "BIN1,SLC4A4,MYRF,CACNA1A,ARHGAP33,WHRN,CLOCK,CREM,CSNK1E,ZNF337,FAM13A,MRNIP,VPS13B,PTK2B,CGREF1,SYT17,ALDH1L1,ZNF276,IL6ST,MAP4,AFDN,OXTR,CCSER2,PLCB2,PLEC,MARCH1,BEND5,RGS12,ZNF821,FAM102A,DOP1A,IZUMO4,PEG10,ZC4H2,PDLIM2,TBCEL,ZFP37,EPM2A,PHTF2" Drug 3545_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,C1QTNF1,ATP2B2,SYNJ2,SCAPER,MTMR7,TPP1,COL9A3,VCAN,DTNB,PLXNC1,HSD17B14,RASGRP2,DLC1,FLNC,FYB1,SEPT9,TOX3,STMN2,LAMA2,SMAD1,ADAM22,NF1,NTRK3,DUSP26,SEPT4,ELOVL2,PTN,PTPRB,RGS4,RGS12,FRMPD1,ABLIM3,SNCA,ATP10B,WSCD1,SEMA3B,NLRP3,JPH3" Drug 4355_UP Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "LTBP4,AMPD3,APC,CFAP410,RUNX1T1,CCK,CNTN1,AKAP6,WHRN,AKAP5,SPOCK2,EXOG,SEMA3D,EGFR,AASS,FYB1,SEPT9,KCNB1,KCNJ5,MMP16,MN1,TAGLN3,NPTX2,P2RY1,MINDY2,CEP41,VPS13C,FAT4,KCTD17,SLC11A1,ARHGAP26,CDK19,KIAA1107,HIF3A,HEY1,TNS1,WIPF1,LAT2,KCNAB1" Drug 3726_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,ADORA1,LTBP4,APAF1,RASL11B,KIF1A,NRP2,BMP7,USP2,TPP1,SULT4A1,CNTNAP2,EDIL3,FCF1,SEMA3D,EGFR,COQ7,NCALD,FGF1,ARFIP1,ADAM28,GLUL,POLL,MATK,MEF2C,NF1,NPTX1,CLDN11,PDE4B,PDE4D,PTPRN2,CCDC40,RAD51D,RFX2,SH3BP2,SPTAN1,MCF2L,TNS1,PLSCR4" Drug 4238_DN Seneciphylline [480-81-9]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADRA1D,APC,APOC1,CDK10,SLC4A4,KIF1A,TAOK2,LHX2,WHRN,ARHGEF10,ARHGAP24,ST3GAL6,FGFR1,OGA,FYN,RUNDC3A,LPAR4,KCNN1,MAPT,AFF1,OGG1,PALM,PDE4B,PLXNB1,PPARA,PRKAR1B,WDR25,ZSCAN32,RGS4,FRMPD1,PEX26,DOK5,TRIM2,TRIO,AMACR,OSBP2,XRCC4,KCNAB1,TIGD6" Drug 5679_DN Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "APC,EPB41L5,ARRB1,ARRB2,ADAM15,BCL7A,CFLAR,SCARB1,SRSF11,CLOCK,CSNK1E,SIPA1L1,ZNF804A,MFAP3L,RCAN1,FEM1B,FECH,FGFR1,PRELID3A,TRAF3IP2,MALT1,GLYR1,MSL3,HNMT,ICA1,MAPT,MATK,LYRM9,CNOT4,PLXNB1,PRPH,RAD51D,FBXO11,EPN2,ZBTB43,TACC1,TPM1,HIRA,LMF1" Drug 2953_DN Lymecycline [992-21-2]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AP2A2,ZBTB10,MTMR2,QKI,PPP1R16B,RUSC2,DTNA,FAM13A,ACSL4,FLT1,TRMO,CAMKK2,CELF1,DISC1,SRCAP,ADAM28,LSS,MX1,GPR85,LRP12,MINDY2,PPP3CC,PPP5C,FAM184A,FAM192A,SLC2A5,FAM214B,SLC6A8,KDM4B,KLHL7,DNMBP,TMPO,TNS1,HIRA,FLRT2,TFIP11,EMSY,HPS4,PHTF2" Drug 4812_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "OSBPL1A,AK2,ATP6V0A1,SCARB1,USP6NL,TSPAN5,FEM1B,DCTN4,DENND4A,ANKMY1,MALT1,GPR37,ELOVL5,DHX35,IPO5,NF1,CCSER2,SLC25A23,STRN3,PTK2,CEP97,SEC14L1,ELMO2,BTBD7,LIMCH1,RBM34,KDM3A,TROVE2,SS18,PHLDB1,SYT1,TACC1,RUNDC3B,LMF1,ZNF32,EVI5,MPPE1,PHTF2,RNF146" Drug 3729_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "SYN3,MTUS1,BEGAIN,SLC2A11,BAIAP3,CFAP410,RUNX1T1,CNOT8,RAB28,SULT4A1,RAB26,RIMS2,DRP2,EDNRA,FCF1,EPHB1,NCALD,OLFM1,MIA2,MMP16,PDE4D,PFKFB4,MTRF1L,STRN3,WDR25,RGS4,PEX26,ARHGEF40,HECW1,CDK19,DDN,NFASC,ZEB1,CRTC1,KAT6B,TRIO,XRCC4,KAT6A,PHTF2" Drug 3070_UP Metyrapone [54-36-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ALK,TRMT9B,APBB2,PPP4R4,MYOM1,HIP1R,C2CD2,CREM,ABCG1,PDE4DIP,ARHGEF4,SPOCK2,RUSC2,DLC1,OLFM1,FGFR1,BAIAP2,GABRG2,ALDH1L1,GNG4,GPD1,GRM8,TJAP1,MAP4,AFDN,ADAM22,NPTX2,NTRK3,PFKFB4,RASA3,ST6GAL1,KANSL3,DOK5,SEPT8,STX1A,SYN2,PCDHGB6,TNS2,NT5M" Drug 6293_UP Melatonin [73-31-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NME5,ALK,SEMA7A,NRP2,BAIAP3,CACNA2D1,CAMK2B,TAOK2,TBC1D5,SGSM2,TUBD1,RASL10A,ZNF44,GAD1,SESN1,USP19,GLI2,CNTRL,SPACA9,CACFD1,HNMT,ITPKA,KCNJ5,KIFC3,MAPT,MYT1,SERPINI1,PPP2R2B,SAMD9,RGS12,STUM,DDN,PHLDB1,SYN2,KIAA1107,DOCK9,CRTC1,NT5M,KCNAB1" Drug 4840_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "BRAP,PKP4,APBB2,PPFIA3,CDC14B,CDK10,ATP6V0A1,CFLAR,RAB29,KRIT1,SCARB1,PLEKHB1,AKAP7,WHRN,COL4A5,FCF1,IRAK4,ENO2,PRKAG2,DISC1,MALT1,CRCP,DHX35,KCNF1,MAP4,MBD1,RETREG1,SLC25A23,RAD51D,SLC6A8,SPATA7,SS18,SLC44A1,RUNDC3B,SPHK2,REEP1,EVI5,URM1,UBE3B" Drug 1729_DN Iobenguane sulfate; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "APBB2,CDC14B,STX16,BARD1,BTK,SPAG9,PLAA,CLCN3,CLTB,PREPL,PPP6R2,RUBCN,DCAF8,KIAA0586,ZNF804A,MBNL2,EIF5,HTATSF1,PRRC2B,MAP4K5,HNMT,NF1,KCTD15,TRHDE,PPP2R2B,ZSCAN32,ATXN2,TROVE2,SS18,MCF2L,WBP2,TRPM2,SSBP2,HIRA,VIPR2,LAT2,TRIM9,PDSS2,EPM2A" Drug 6158_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ASPHD1,ADORA1,ALK,BCAS1,CDK10,CACNA1I,MYRF,HAP1,CHRNA4,NRG2,FAM169A,E2F5,SRPK3,HSD17B14,RCAN2,ERBB4,RASL12,OLFM1,AGAP2,GAD1,GFER,RUNDC3A,GUCY1B1,AFDN,MYO7A,MYT1,NELL2,PNMA3,SEPT4,RASGRF1,KHDRBS2,RPS20,FERMT1,EPN2,PHLDB1,TCF4,DOCK9,SLC19A3,SLC17A7" Drug 4733_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADORA1,LGR5,KSR1,SCAPER,BAIAP3,CAPN3,CBARP,ARHGEF6,CNTN1,AKAP6,VCAN,DGKG,SPOCK2,RASGRP2,MTSS1L,IGSF6,PRELID3A,CSPG5,SIGLEC8,LYVE1,LILRA2,GRIK5,SYNPO,TJAP1,KCNJ5,KIF5A,AFDN,MSR1,MYT1,NOVA2,OGG1,SNRK,RGS4,TCP11L1,MRAS,PCDHGB6,AMACR,KCNK12,KCNAB1" Drug 5629_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NME5,AMPH,CDK13,KSR1,CDO1,CNN3,NCOR2,CYBB,RASSF2,AASS,ING4,EPHB1,FGF13,FUT9,RUNDC3A,POLL,TJAP1,KCNQ3,AFDN,MMP17,OPRL1,PLCD1,LRRN3,CEP41,MAPK10,GDPD2,CNTLN,NUDT11,SUGCT,PKNOX2,TSNAXIP1,ATP10B,RGL1,WSCD1,UBE3A,CLIP2,XRCC4,SLC30A3,KCNAB1" Drug 3758_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "CDC42BPA,KCNAB2,GAS7,ZSCAN18,ADAM23,BMP7,SCAPER,ARHGEF2,AKAP5,CRMP1,HAPLN1,TOM1,ING4,SPEG,ETV1,PTK2B,EFCAB2,NEU3,GFER,CACFD1,TJAP1,ITPKA,NF1,PDE4D,SNRK,BEND5,ASAP3,PEX26,ATP10B,SYT1,KIAA1107,GPR161,TIAM1,TNS1,CDK20,HIRA,VGF,XRCC4,TIGD6" Drug 4107_UP Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "ADD2,ADGRF5,TRMT9B,RGS20,SYNJ1,RUNX1T1,WHRN,CRY2,SUSD5,CDON,PLEKHA1,ETV1,DLC1,FUT9,NEU3,GCNT2,GFER,GPR37,ICA1,ITGA7,KCNN1,NF1,NOVA1,NTRK2,GPR85,PPARA,MAPK7,GDPD2,RGS3,SH3BP2,FBXO11,SP4,PLCB1,KIAA1107,WIPF1,LAT2,SLC30A4,TIGD6,JPH3" Drug 5276_DN "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "AK2,APC,CDK10,SEMA4G,DNAH17,MARK4,CFLAR,CNTN1,AKAP7,CRY2,PDE4DIP,RASSF2,JAKMIP2,MFAP3L,EXOG,EGFR,MBNL2,PIPOX,DLC1,FGF13,OGA,GAD1,GNG4,KPNA5,KITLG,ZNF862,MINDY2,RPS20,PREX2,SLC9A5,MAPKBP1,ZHX3,SYNE1,PCDHA5,DICER1,AP4E1,VIPR2,VLDLR,ZNF45" Drug 1894_UP Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HG-U133A Broad Institute CMAP Up 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG3,ADORA1,AP2A2,KCNAB2,APBB2,N4BP2L1,ATP6V0A1,SCAPER,CNOT8,CNTFR,CSNK1E,ARHGEF4,SPOCK2,KLHL3,TMCC2,SRPK3,TUBD1,STX2,ATP2C1,PRRC2B,GSTM5,NXPH3,IFI16,GIT1,NTRK3,NUDT11,NCBP3,EPN2,HECW1,UNC5B,CDK19,VPS13A,IQCE,SSBP2,VSNL1,CLIP2,EVI5,PRDM10,SMIM8" Drug 2229_DN Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG2,LTBP4,APC,PPFIA3,ATP6V0A1,CFLAR,ARHGEF1,SLIT2,PICK1,AKAP7,CRY2,CSF1,CSF1R,SEC14L5,SPACA9,GSTM5,RASSF8,HNMT,INPP5B,KIF2A,ADAM22,NF1,CNOT4,PALM,PRODH,GSTCD,FAM214B,BTBD7,SNCA,TROVE2,THSD1,PLCB1,ARC,ASTN2,PCDHA6,VLDLR,LMF1,SPHK2,EMSY" Drug 262_DN "indomethacin, USP; Down 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "KIAA1324,RASL11B,SLC4A4,CBLN1,ARHGAP33,CACNA2D2,SIPA1L1,KLHL3,EDNRA,NSG1,LUZP2,GNAO1,LILRA2,BTN2A1,AP4S1,SYNPO,HNMT,IGF1,KIT,LAMA2,STMN1,MATK,SLC11A2,SETD4,PTK2,ZCWPW1,KLHDC8A,SH3BP2,FERMT1,SLC6A11,SLC8A1,KBTBD4,ZC3H13,TACC1,FAM208A,DOCK9,CDH22,RIMBP2,TFIP11" Drug 4747_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "NDRG3,NME5,TRMT9B,BIN1,AMT,GAS7,PLA2G4C,MPDZ,TAOK2,QKI,MAML1,ING4,NCALD,TRMO,DISC1,INPP5K,POLL,GRB10,MEF2C,MMP16,ZNF862,NF1,NFYA,RGS3,GSTCD,SBF1,SH3BP2,ZHX3,CEP68,NSFL1C,EXOC7,SZT2,CHST8,TK2,TNS1,RUNDC3B,HIRA,LMF1,MPPE1" Drug 3113_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.37E-04 1.00E+00 3.63E-03 4.09E-02 39 196 "PKP4,KCNAB2,SLC4A4,ATP6V0A1,BCL7A,LDLRAD4,CBFA2T2,SCARB1,CD38,CLCN3,CNTN1,CREM,ERCC2,PTK2B,SCML2,ST3GAL6,CGREF1,HTATSF1,CACFD1,SMAD1,MAP4,MATK,MYO9A,NINJ2,OGG1,PIK3R1,CCSER2,SLC25A23,DGLUCY,SATB1,SEC14L1,ANKRD6,TMCC1,IQSEC2,TNS1,TPM1,UBTF,LMF1,ATP6V0E2" Drug 5981_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.41E-04 1.00E+00 3.68E-03 4.14E-02 37 183 "ADRB2,CDC14B,ARNTL,ST3GAL5,HIP1R,USP2,ABCG1,PDE4DIP,CTH,PLPPR4,EDNRA,RASGRP2,PTK2B,TAOK3,BAIAP2,GNAO1,STON1,GUCY1B1,KCNH2,LIFR,MATN3,CDK18,SERPINI1,RETREG1,PLCD1,PRPH,RASGRF1,FAM102A,SH3GL3,AMBRA1,SOX15,ELOVL4,RGL1,ARC,SYT1,RUNDC3B,TRIM9" Drug 7507_UP daunorubicin HCl; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.41E-04 1.00E+00 3.68E-03 4.14E-02 37 183 "ABR,APC,APLP1,PRX,CFLAR,BMP7,P2RX6,RCBTB2,SLIT2,WHRN,ABCG1,DMPK,MED12,F8,FGFR3,SYT17,ALDH1L1,SESN1,AGBL5,IL6R,INPP1,MITF,NPTX1,PDE4A,PPP2R2B,SNRK,TMEM231,C1orf54,RAP1GDS1,ZNF821,SLC6A8,SNCA,SS18,ELOVL4,ARC,ZMAT3,ZNF34" Drug 6339_UP Pyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.41E-04 1.00E+00 3.68E-03 4.14E-02 37 183 "C1QTNF1,ATP2B2,CACNA1I,CACNA2D1,HAP1,CARS,ARHGEF2,ZMYM4,SULT4A1,CREM,ENTPD4,AATK,CTH,FGFR1,PRELID3A,ZNF44,TRAF3IP2,MTHFD2,ALDH1L1,GRB10,IL6ST,IL12A,ITPKA,MIA2,NCAM2,NOVA2,PDE4D,PTPRN2,GAL3ST4,ZNF821,ATP10B,ZNF34,HEY1,LMF1,LAT2,SEMA3B,SLC17A7" Drug ctd:D005472 Fluorouracil CTD 3.56E-04 1.00E+00 3.84E-03 4.32E-02 195 1364 "MTUS1,ALCAM,AMPD2,AMT,EP400,APAF1,APBA2,APBB2,UPRT,APOC1,ZSCAN18,ZNF582,BID,BLM,CFLAR,PROM1,DST,GYG2,SGCE,CA12,CALB2,PRC1,CBS,CD38,LRBA,CDC25B,DCLK1,TBRG4,NOG,RCBTB2,SRSF11,FOXN3,PLEKHB1,CHRNA4,CLCN3,TPP1,CLTC,ABCG2,TMEM184B,MAGED1,SEC31B,PREPL,CRHBP,AKAP12,NCOR1,NCOR2,CSF1,CSNK1E,KIAA0040,PUM1,HDAC4,DAPK1,ALKBH8,FAM107B,NR1D2,PDCD6IP,ABCC5,EDIL3,EDN1,EDNRA,OPTN,EGFR,EIF5,PCOLCE2,ELN,TUBD1,SRRM1,ERBB2,ERBB4,ERCC2,F8,ARMCX1,TUBB3,TAOK3,DLC1,PPP1R1B,OLFM1,MAD2L2,PRKAG2,SYNCRIP,AGAP3,FOXO3,FLT1,PDLIM5,FYN,GABRB3,IQGAP2,SEPT9,TUBA8,GDF1,SESN1,MALT1,DBF4,CBX1,FERMT2,GP1BB,AP4S1,GUCY1B1,MAP4K5,ATOH8,HBA1,ELOVL5,ACOT7,IFI16,IGF1,RBPJ,KHK,KIT,L1CAM,TTYH2,LIFR,LSS,MAP2,MAPT,MBNL1,MBP,KITLG,MT1M,MXI1,MYCN,MYO6,NBL1,NEK1,NFE2L2,NFYA,NME4,NTRK2,GPR137C,PAX6,ABCB1,SMOX,SLC25A23,PURG,MAPKAP1,EXOSC10,POLG,PPP3CA,KANSL1,MAPK3,MAPK7,KLK6,LAMA1,PTCH1,PTK2,NKAIN1,RDX,RGS4,ZNF532,SETD5,MCMBP,SCN2B,SEC14L1,MRAS,FAM102A,SHMT2,R3HDM2,SEC31A,SEPHS1,ELMO2,ARFGAP1,ZKSCAN3,ANKRD36,KDM4B,FNBP1,UNC5B,PEG10,DBNDD2,MESP1,SST,MPRIP,STAU1,NEK4,KLHL7,SYP,MMS19,TRIM2,PCDHA5,TEK,DICER1,ZMAT3,TK2,PARD3,TPM1,STXBP4,CA14,TSC2,TST,UCHL1,UGT8,FLRT2,LMF1,ZNF32,NT5M,ADAMTS9,NETO2" Drug 462_UP troglitazone; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "ABHD6,NDRG2,SYT13,AMT,APBB2,SLC4A4,CALB2,LARGE1,CLCN3,LY86,C2CD2,SH2B1,CRMP1,NCOR1,SIPA1L1,ARHGAP24,HS3ST2,DRP2,EXTL2,DLC1,DLL3,GRIK5,RASSF8,KCNJ5,MN1,GAL3ST4,RGS4,MAP6D1,FAM214B,PKNOX2,ARHGEF40,TMCC1,ZC3H13,TSPYL2,VAV1,ZNF24,SLC17A7,PLSCR4" Drug 3041_DN Luteolin [491-70-3]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "ADRB2,AMPD3,ANK2,NCOA1,SCAPER,CBR1,PLAA,ARMC8,SLITRK5,HDAC9,GIT2,RHOBTB1,EXOG,NR1D2,DTNA,VPS13B,SYNCRIP,IRF8,IFI16,KCNN2,PDCD2,GPR85,TRHDE,PTCH1,HSPA4L,ARHGEF40,FNBP1,CEP68,KANK1,EXOC7,TCF4,ZEB1,PARD3,TNS1,SSBP2,UBTF,XRCC4,PHTF2" Drug 7305_DN Econazole nitrate [24169-02-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "C1QTNF1,SHROOM2,CASK,ADAM15,CFLAR,ARHGEF1,RAB28,NRXN3,QKI,NCOR2,DZIP3,USP6NL,ARHGAP32,GIT2,LYPD1,TAOK3,ANKFY1,NOP56,PDLIM5,FYN,GLYR1,MSL3,AGFG1,KIF2A,MEIS1,NF1,FSD1,SH3TC2,FAM102A,PEX26,KBTBD4,ZKSCAN3,ZNF415,CEP68,TMPO,TNS1,RUNDC3B,XRCC4" Drug 2375_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "NDRG2,ADORA1,APBB2,ATP2B2,ST3GAL5,MYRF,CFAP410,CAMK2B,CHN2,CRMP1,ABCG1,PDE4DIP,DZIP3,PPP1R16B,GSDME,EGFR,ENO2,ETV1,PIPOX,FGFR1,INPP5K,SLC2A6,FAM69A,ITGAM,MEF2C,NF1,SERPINI1,PLCD1,PMP22,KCTD17,FAM214B,RGL1,STXBP1,DNMBP,TPM1,TRIM9,REEP1,EVI5" Drug 6697_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "ACTN1,PPFIA4,APAF1,APC,DDO,ATP6V0A1,RUNX1T1,CBS,TAOK2,QKI,NCOR2,CSF1,VCAN,PDE4DIP,RIMS2,MFAP3L,EDN1,MBNL2,TNK2,ZNF589,STMN2,MBP,ADAM22,NNAT,P2RY1,RETREG1,NLE1,LRRN3,PTX3,PKNOX2,CDK19,PDLIM2,RPGRIP1L,CHST5,TRIO,UBE3A,ZNF24,NAV3" Drug 4144_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "NME5,AK2,AMH,CDC14B,SLC2A11,CFLAR,SYNJ2,NCOR2,CSF1,BRINP1,EDNRA,FGFR1,AGAP2,DCTN2,NSG1,TMEM8B,GATM,SRCAP,GFER,ATXN2L,KIF5A,CNOT4,GPR85,RETREG1,MAPK7,GDPD2,PTPRB,ENOX1,GSTCD,PKNOX2,HECW1,UNC5B,JMJD6,SLC35G2,R3HDM1,TNS1,MKRN3,SLC30A3" Drug 5821_UP Tetrandrine [518-34-3]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.59E-04 1.00E+00 3.86E-03 4.34E-02 38 190 "MTUS1,APBB2,LGR5,ARNTL,ST3GAL5,C5,IL33,AKAP7,SUSD5,VCAN,CTH,FAM13A,TENM1,MRNIP,RRAGB,NRN1,FDFT1,GABRG2,TDRKH,HMGCR,AFDN,GIT1,MT1M,TAGLN3,NTRK2,GDPD2,SUGCT,NEK11,TCP11L1,ASAP3,FAM214B,IFT122,IQSEC2,SYT1,KIAA1107,TNS1,HIRA,CLDND1" Drug 1643_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-04 1.00E+00 3.89E-03 4.38E-02 36 177 "OSBPL1A,BIN1,CFLAR,ST3GAL5,CAMK2G,CNOT8,CSF1,PDE4DIP,CTH,PUM1,DBT,MFAP3L,RCAN1,MBNL2,ARMCX1,ZNF589,SEMA4D,OGA,ERAP1,DISC1,MSL3,GNG4,DIDO1,HMGCR,IL6R,OXTR,MBOAT7,HSPA4L,SH3BGR,FNDC3A,BTBD7,TSPYL2,TRIM2,VGF,FXR1,SENP7" Drug 2938_UP Alprostadil [745-65-3]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.67E-04 1.00E+00 3.92E-03 4.42E-02 31 145 "ABHD6,MTUS1,BIN1,DNAH17,CFLAR,ST3GAL5,LDLRAD4,CD86,CD38,CHN2,CREM,ABCG1,SIPA1L1,DOCK4,KLHL3,MAMLD1,FAM13A,PRKAG2,PDE4B,PDE4D,SERPINI1,SMOX,QDPR,TMEM255A,SGK1,SPTAN1,SAMSN1,PLCB1,TRPS1,FLRT2,ZBTB38" Drug CID000002951 Dantrolene-13C3 Stitch 3.67E-04 1.00E+00 3.92E-03 4.42E-02 31 145 "AGT,AK2,APOC2,ATP2A2,CACNA1I,CACNA1G,CA4,CA8,CA12,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CACNA2D2,DMD,HIPK3,CAMKK2,GRIN2C,GRIN2D,GRM2,GRM8,IL12A,NBL1,PIK3C2A,PKD1,QDPR,RYR3,TPCN2,CA14,RTN4" Drug 5803_UP Propidium iodide [25535-16-4]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA1,NME5,GAS7,ARSE,KIF1A,NRP2,BMP7,CHN2,STOML1,HOMER3,ARHGEF10,RIMS2,ARMCX2,EDIL3,FRY,ING4,MTSS1L,ANKMY1,HPCAL4,SYT17,GATM,SPACA9,ATXN2L,JAK2,LAMA2,LSS,AFDN,MMP17,PDE4A,PPP2R2B,PTPRB,PID1,CCDC40,ENOX1,RGS12,DZIP1,IQSEC2,LAT2,KCNAB1" Drug 6737_DN Ethaverine hydrochloride [985-13-7]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADRB2,MTUS1,BIN1,CDK10,PDE8B,ATP1A3,ATP2A2,KIF1A,CAMK2B,AKAP7,NRG2,NCOR2,ARHGEF10,HDAC9,MRNIP,HSD17B14,SPEG,DLC1,ST3GAL6,GPER1,INPP5B,KPNA5,LIG4,MYT1,NF1,NFIX,SLC11A2,PTN,RIPOR1,SBF1,SLC14A1,TMCC1,SUPT5H,SYT1,PCDHA5,TNS1,VIPR2,KCNAB1,ACTR3B" Drug 3543_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADGRF5,ALCAM,SRPX,APBB2,SEMA4G,AZGP1,CFLAR,CACNA1I,LDLRAD4,SLIT2,ARMC8,SNCAIP,SOCS5,DOCK4,RASSF2,DTNA,IGSF6,ZNF589,FECH,KHDRBS3,FYN,GALC,MALT1,HNMT,IL6R,KPNA5,MSR1,NOVA2,NPR2,MINDY2,PPP2R2B,FAM184A,SYBU,PDZRN3,SS18,KIAA1107,DMXL2,UBE3A,XRCC4" Drug 1305_UP Carcinine [56897-53-1]; Up 200; 22uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "PPFIA4,NUMB,SYNJ1,SYNJ2,GYG2,MYRF,SLC25A14,CBFA2T2,AKAP6,SH2B1,CSF1R,VCAN,PPP1R16B,DOCK4,RUSC2,C2CD2L,DTNA,PCDH17,MSL3,GRIK5,IRF8,LSS,MEF2C,SLC11A2,PFKFB4,SLC25A23,MAPK7,BCAS3,RNASEL,ZNF671,MAP6D1,FAM214B,SNCA,DOP1A,CEP68,ARHGEF9,EXOC7,DMXL2,TRPS1" Drug 4715_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NME5,PDE8B,SLC4A4,CFLAR,CA4,ARHGEF1,MAGI1,TAOK2,RGS6,FAM169A,TBC1D5,MAML1,EGFR,FGFR3,AFF2,ZNF44,GATM,GLYR1,GRIK5,HLF,IL6ST,MID1,NF1,MAPK10,NKAIN1,SUGCT,TCP11L1,MRAS,ASAP3,SMARCD3,SNCA,PHLDB1,PLCB1,SYN2,SYP,TCF4,DMXL2,CHST8,SEMA3B" Drug 5792_UP Butamben [94-25-7]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD2,TRMT9B,EPB41L5,DDO,BCAS1,NRP2,CBLN1,CD86,ARHGAP33,LARGE1,ARHGAP22,RCHY1,ARMCX2,COQ7,LRRC17,DISC1,GATM,ALDH1L1,GPD1,GRIK5,ELOVL5,ITGA7,KCNH2,KHK,MATK,NTRK2,PFKFB4,CEP41,PTPRN2,PNMA8A,STUM,PPP4R3A,KIF13A,TCF4,AMACR,VSNL1,REEP1,SLC30A4,PARP11" Drug 6222_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APOC1,ARRB1,PDE8B,ADAM15,SYNJ1,ST3GAL5,QKI,PDE4DIP,DZIP3,MFAP3L,SPOCK3,RCAN1,ING4,DLC1,FER,OLFM1,MPP6,OGA,LYVE1,HTATSF1,GPR37,GRM8,IL6ST,INPP5B,MATK,NACA,NF1,C1orf54,RNASEL,NEK11,SYBU,SS18,TTBK2,TMPO,NR2C2,OSBP2,GDPD5,MPPE1,UBE3B" Drug 6747_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALK,FAM131A,N4BP2L1,BMP7,GYG2,CFAP410,CACNA1A,CACNA2D1,CD86,RAB33A,SULT4A1,CNTFR,SLC4A8,ARHGAP24,EDNRB,NRN1,AGAP2,ALDH1L1,ELOVL5,FAM69A,MARK1,KITLG,ADAM22,TAGLN3,NF1,NPR2,NTRK2,P2RY1,PDE4B,GPR85,RETREG1,PTH1R,ZFP30,HKDC1,PREX2,TROVE2,SYP,TK2,RUNDC3B" Drug 2427_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SYN3,NDRG3,ADORA1,FAM131A,MPDZ,KSR1,SGCE,CACNA2D2,DZIP3,TM9SF4,EDNRA,EIF1,FGFR1,INPP5K,NEU3,ALDH1L1,IL6ST,MYO6,NTRK2,PGAM2,MTRF1L,PPARA,CNNM2,WDR25,RFX3,ZFHX4,MAP6D1,SEC14L1,SH3BGR,PREX2,CXXC4,ATP10B,SEPT8,MTCL1,TAL1,RPGRIP1L,PCDHGB6,PCDHGA10,SLC17A7" Drug 3453_UP Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "RALGAPA1,ABHD6,DOC2A,AMPD3,KCNAB2,APOC1,CFLAR,CA12,CDO1,ENTPD4,SH2B1,CNTNAP2,FAM169A,GREB1,EGFR,SEPT9,USP19,INPP5B,MSI1,PLXNB1,MBOAT7,ELOVL2,KHDRBS2,SH3BP2,CCDC92,FAM214B,COA1,MAPKBP1,SOX3,ZHX3,ZBTB43,ATP10B,STXBP1,KIAA0930,PCDHA5,CHST8,THRA,TRO,REEP1" Drug 3996_DN Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APBB2,GAS7,SLC4A4,ST3GAL5,SLC25A14,HOMER3,WHRN,ARHGEF10,CSNK1E,DZIP3,PARD6A,ENO2,MFSD10,SPEG,VPS26C,FGF1,ZNF276,MSL3,TDRKH,LPAR4,GPER1,PCLO,BACH2,INPP5B,JAK2,SETD4,PCDH9,PIK3R1,FAT4,ENOX1,GTDC1,ASAP3,TMCC1,ST5,ZNF34,UGT8,HPS4,MPPE1,PDSS2" Drug 5466_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA1,ALK,GAS7,APLP1,CDK13,MARK4,CFLAR,BAIAP3,CAMK2B,ARHGAP33,CACNA2D2,OSBPL3,ZNF804A,HEYL,EZH1,OLFM1,TPK1,PRELID3A,SIGLEC8,ALDH1L1,TDRKH,LIG4,LMO2,AFDN,MMP16,ADAM22,NNAT,OGG1,SERPINI1,LRP12,SEPT4,ZDHHC14,RFX2,MRAS,FAIM2,CEP68,KIAA1107,RPGRIP1L,EVI5" Drug 2781_UP Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG2,AMPD3,BIN1,APC,SYNJ2,CAMK2G,SLC16A4,RAB33A,HOMER3,SH2B1,RIMS2,INTS1,EGFR,MBNL2,FHL1,AFF2,GPER1,SPACA9,INPP5B,KCNJ5,SMAD1,MAP4,ADAM22,NTRK2,MINDY2,PTN,FAM184A,RPS6KA2,KCNIP1,SEC14L1,KDM4B,IQSEC2,TROVE2,CLSTN2,DICER1,HIRA,LMF1,WIPF1,LAT2" Drug 2512_DN Anabasine [494-52-0]; Down 200; 24.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APC,NCOA1,N4BP2L1,ADAM23,ST3GAL5,SYNJ2,ENTPD6,HOMER3,RUSC2,DTNA,MRNIP,RASGRP2,VPS26C,ZNF589,SEPT9,LILRA2,SLC2A6,MYT1,NCF2,NEFH,NF1,CNOT4,RETREG1,PLCB2,PLTP,LRRN3,GSTCD,FAM102A,FAM214B,ARHGEF40,MYH15,KDM4C,PLCB1,EXOC7,FLRT2,XRCC4,ZNF32,UPF3A,ST7" Drug 3940_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AMT,CDC42BPA,APBA2,CACNA1I,CFAP410,CACNA2D1,SEPT7,LY86,CRY2,SNCAIP,PLXNC1,ELN,ERCC2,ZNF391,HPGDS,POLL,GNAO1,STON1,ICA1,TJAP1,LRP1B,NTRK2,NTRK3,PFKFB2,CEP41,GDPD2,TRIM68,SCN8A,CNKSR2,FAIM2,NMNAT2,ATP10B,ZC4H2,CHST5,TRPM2,HIRA,TUBB1,ADAMTS9,AP3B2" Drug 2773_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ADORA2A,NME5,APAF1,APC,MARK4,ST3GAL5,CFAP410,RCBTB2,HOMER3,PICK1,CNTN1,AKAP7,RCHY1,CREM,CRMP1,ARHGEF10,SHANK1,MBNL2,SPEG,ANKMY1,MAP4,GIT1,NF1,PLTP,LRP12,MINDY2,PTPRE,RFX2,ZFHX4,CARF,ASAP3,CXXC4,IQSEC2,TBCEL,ZEB1,UCHL1,KCNAB1,EPM2A" Drug 1528_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA2A,ADRA1D,ALK,AMPD3,KCNAB2,PPP4R4,MARK4,NCOA1,RASL11B,RUNX1T1,ARHGEF1,ARHGAP33,TAOK2,CNTN1,WHRN,NRG2,ENTPD4,MFAP3L,TOM1,ZNF589,FGF1,TDRKH,GSN,TJAP1,MATK,MID1,ADAM22,NEK1,PTPRD,KCTD17,SEC14L1,RBM34,PEG10,STX1A,EXOC7,SZT2,BHLHB9,PIK3R5,KAT6A" Drug 3416_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "C1QTNF3,SRPX,CDC42BPA,PKP4,PPP4R4,CFLAR,SLIT2,TPP1,FAM189A2,PICK1,COL9A3,MAML1,ELN,MTSS1L,SCARA3,OGA,GAD1,POLL,LPAR4,LAMA2,MBD1,MIA2,NF1,LRP12,RGS12,ZFHX4,CARF,ASAP3,ARHGEF40,SLC9A5,BTBD7,SNCA,ST5,PHLDB1,TACR1,PCDHGA10,TK2,PARD3,ZKSCAN5" Drug 2248_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADRA1D,APAF1,ADGRB2,SYNJ1,CA12,CAMK2B,CD86,ASIC3,FAM149A,RASSF2,RUSC2,DMPK,SNX29,EPHB1,SPEG,APC2,AGAP2,GAD1,MSL3,GNAO1,MAP4,MATN3,KITLG,TAGLN3,ZNF862,NELL2,NNAT,PLCD1,LRP12,RGS4,ZFHX4,SH3GL3,ASAP3,ST6GAL1,TPM2,KCNK12,SLC17A7,KCNAB1,PARP11" Drug 337_UP felodipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,BRAP,ALK,BIN1,ARNTL,BMPR1B,CACNA1A,SCARB1,LHX2,SMARCAL1,EDNRB,EPHB1,STX2,BAIAP2,TRMO,CAMKK2,FYB1,ERAP1,COPS8,GNAL,LILRA2,RASSF8,ATXN2L,ITPKB,L1CAM,SLC11A2,SETD4,P2RX7,MASP1,KCTD17,SH3GL3,LHPP,TACR1,TBL1X,DOCK9,PARD3,PLPPR2,WIPF1,ZNF23" Drug 3182_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD1,LTBP4,MARK4,ATP6V0A1,KIF1A,C5,CAMK2G,CLCN3,STOML1,ARHGEF6,AKAP7,ZNF337,DBN1,EIF5,ANKFY1,ZNF44,GALC,SYT17,MALT1,CNTRL,HNMT,KCNH2,LMO2,MAPT,MIA2,NF1,CNOT4,RETREG1,WDR25,RPS6KA2,SBF1,ZNF821,EPN2,KDM4B,CLASP2,POGZ,KIAA0930,TNS2,CABIN1" Drug 4319_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "CDK10,ADAM15,FUBP1,KALRN,HAP1,LARGE1,DZIP3,TBC1D5,SPOCK3,EDN1,HIPK3,TUBD1,EPB41L2,EZH1,KAT8,FHL1,GPER1,SHISAL1,KITLG,OPRL1,PALM,PFKFB4,PTPRN2,GAL3ST4,FBXW7,ATXN7,ZNF821,SLC12A4,ELMO2,ZNF667,IQSEC2,SZT2,CRTC1,SMUG1,UBE3A,XRCC4,ZNF24,NDRG4,PHTF2" Drug 6679_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "RALGAPA1,ADRA1D,LTBP4,ANK2,KCNAB2,ARRB1,RASL11B,ATP2B2,ATP6V0A1,SYNJ1,GYG2,KALRN,CRLF1,NRXN3,CDON,DUSP9,F5,SIGLEC8,LYVE1,SPACA9,CACFD1,ATXN2L,IRF8,MGAT3,ADAM22,NPY,CLDN11,GPR85,ZSCAN2,ENOX1,TCP11L1,STUM,SLC11A1,SNCA,EXOC7,ICAM5,TLR4,SPHK2,PARP11" Drug 6810_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG2,BIN1,OGT,FGD2,APLP1,CDC14B,ATP2B2,CACNA1G,CFAP410,ARHGEF1,CLGN,WHRN,CRMP1,PDE4DIP,MAML1,DTNA,DTNB,FYN,SEPT9,GPD2,GPER1,KCNN2,KCNQ3,ZNF862,PDE1C,ELOVL2,SUSD4,TRIM68,TCP11L1,RASA3,FBXO11,BTBD7,LIMCH1,SLC19A3,RUNDC3B,AMACR,VIPR2,SPHK2,ITM2C" Drug 4391_UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,APAF1,AZGP1,CFAP410,HIP1R,TAOK2,TPP1,CSF1,IPCEF1,VCAN,DCAF4,RIPOR2,ARHGAP24,MYEF2,EDN1,EPB41,SPEG,DCTN2,GAD1,GRIK5,GRM2,ITGA7,MATN3,MYO7A,NPY,OPRL1,CLDN11,GPR85,PILRA,RGS12,KANSL3,OGDHL,SNAP25,SNCA,CUX2,FAM189A1,SLC30A3,ADAMTS9,ITM2C" Drug 2733_DN Methazolamide [554-57-4]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ABHD6,AMT,CDC42BPA,APAF1,APBB2,MADD,NUMB,CD86,CLGN,QKI,KIAA0753,FCF1,COQ7,ERCC2,NCALD,ZNF589,ANKFY1,PDLIM5,GNG4,LILRA2,ITGAM,LIG4,MEF2C,MIA2,NF1,NINJ2,PDE4A,CCSER2,PLEC,CARF,ZFP30,TROVE2,PLCB1,KIAA1107,PIK3R5,SMUG1,SSBP2,XRCC4,ZNF225" Drug 6475_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG2,ADCY6,ADGRF5,KCNAB2,PPFIA3,PRX,CDK13,N4BP2L1,AZGP1,KSR1,SGCE,RUNX1T1,RAB33A,QKI,EDN3,DLC1,FGF1,FGF13,ANKFY1,NSG1,DHX35,ICA1,KIT,NEFM,NF1,CNOT4,PFKFB2,PLXNB1,POLG,C1orf54,GSTCD,FAM214B,PDZD2,ARHGAP26,TEK,AP4E1,TLR4,TPM1,MKRN3" Drug 1711_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; HL60; HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "C1QTNF1,BEGAIN,APAF1,SEMA4G,CAMK2B,P2RX6,RAB26,HINFP,RUBCN,DBN1,GSDME,ACOT8,PHF20L1,ING4,IGSF6,EZH1,CINP,GALC,DIDO1,GRIK5,SETD4,PLCD1,MAPK10,CNNM2,DPF2,MRPS18A,C12orf49,SUPT20H,CCDC88A,SPTAN1,CAMTA2,THSD1,SS18,STX1A,TRPM2,TSN,LAMP5,NT5M,SMIM8" Drug 4832_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AP2A2,APC,PRX,CDK13,CFLAR,QKI,COL9A3,BAG4,CRY2,DCAF4,DAPK3,RRAGB,ANKFY1,TRMO,GAD1,GLYR1,SYNPO,IL6R,LMO2,LSS,MMP16,NNAT,NPTX1,P2RY1,PRKAR1B,MAPK7,SCN8A,ASAP3,CCDC88A,RBM26,ATP10B,CLSTN2,THSD1,DOCK9,TMPO,TPM2,PDIA2,VIPR2,NT5M" Drug 2484_DN Terconazole [67915-31-5]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "BIN1,ARRB1,MARK4,SLC4A4,STX16,SLC16A4,TMEM184B,CREM,SH2B1,ARHGAP32,HIPK3,FEM1B,CELSR3,EIF1,FGFR1,SEMA4D,EFCAB2,SEPT9,AHDC1,POLL,SLC2A6,ATXN2L,TJAP1,ITGA7,MAP4,GIT1,PLCB2,PILRA,CNNM2,PTN,PTPRN2,ZDHHC14,SEC14L1,SH3BP2,DBNDD2,IQCE,PARD3,PLPPR2,TIGD6" Drug 2177_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADCY6,BIN1,CDC42BPA,CDC14B,CDK10,ZSCAN18,CACNA1I,CFAP410,SYNGR3,CNN3,PDE4DIP,DAPK1,SPOCK2,MFAP3L,ING4,AGAP2,FLT1,ERAP1,TJAP1,KCNJ5,MAP4,MIA2,PDE4A,PPP2R2B,PRPH,WDR25,PTPRB,PTPRN2,ZNF821,CPEB3,KDM4B,ATP10B,STX1A,SYN2,CRTC1,TK2,TPM1,CDK20,SLC30A3" Drug 1578_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; HL60; HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG3,AMPD2,AMT,CFLAR,RAB29,HIP1R,EPS15L1,PREPL,CREM,HINFP,NCOR1,PUM1,RUBCN,CYBB,ZNF337,TM9SF4,ZNF44,PRRC2B,NACA,NF1,SLC11A2,PDE4A,EXOSC10,MAPK10,TMEM231,DPF2,GSTCD,PCMTD2,NEK11,CCDC88A,SMARCA4,CDK5RAP2,SNAP25,MMS19,TCF4,TPM1,METTL3,ZNF189,ADAMTS9" Drug 2204_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADRA1D,AP2A2,C1QTNF3,ALK,PPFIA4,APOC1,MPDZ,SYNJ2,LDLRAD4,LARGE1,CDO1,AKAP7,SEC14L5,DBT,DTNA,E2F5,FAM13A,STX2,ERCC2,RRAGB,KAT8,MYT1,PLCD1,PPP5C,CEP41,PTPRO,TCP11L1,FNDC3A,LIMS2,DOP1A,IZUMO4,SPTAN1,TSPYL2,JMJD6,ZMAT3,PARD3,ZKSCAN5,VSNL1,EVI5" Drug 5823_UP Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "MTUS1,C1QTNF1,APC,SEMA4G,ATP2B2,KIF1A,CFLAR,CFAP410,NRXN3,USP6NL,GIT2,MFAP3L,KIAA0753,OPTN,TUBD1,LRRC17,ZNF589,TRMO,DISC1,MAPT,MMP17,ADAM22,TAGLN3,NOVA2,NPTX1,PPP2R2B,CNNM2,BCAS3,CNTLN,TMEM231,RASGRF1,ZMAT4,FNDC3A,ANKRD6,KDM4D,TMCC1,MCF2L,CRTC1,CABIN1" Drug 6241_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALK,AMT,APBB2,AZGP1,QKI,RGS6,LRIG1,FAM169A,BRINP1,SUGP2,DLC1,ST3GAL6,ZNF589,BAIAP2,FHL1,CINP,AHDC1,TXNL4A,POLL,INPP5B,KCNF1,KIF2A,AFDN,NNAT,SNRK,WDR25,CEP97,RGS12,RPS6KA2,SGK1,SYBU,KANSL3,TSNAXIP1,SPTAN1,WSCD1,AP4E1,THRA,KAT6B,CABIN1" Drug 4583_DN Terconazole [67915-31-5]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADRA1D,CDK10,SLC4A4,KIF1A,ADGRB2,NRP2,CACNA1A,ARHGAP33,FOXN3,TPP1,HOMER3,PICK1,AATK,ARHGEF10,SNPH,CNNM1,CINP,ELOVL5,HSF2,SCIN,ITPKB,MAPT,MITF,LYRM9,NDP,POLG,ELOVL2,ZCWPW1,SUGCT,DCUN1D2,TCP11L1,ASAP3,ZNF334,LIMCH1,SNCA,ZHX3,DDN,VGF,XRCC4" Drug 3683_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NME5,BCAS1,ATP1A3,ADAM23,CACNA1I,CACNA1A,LDB2,CBFA2T2,RAB26,APC2,HPCAL4,DCTN2,FOLR2,RUNDC3A,GNAL,GPD2,PRUNE2,GRM8,ICA1,IGF1,MARK1,MSR1,LYRM9,MYT1,NNAT,CDK18,PGAM2,PNMA3,SUGCT,RYR3,SOX15,HECW1,TACR1,PIK3R5,LAT2,SPHK2,SEMA3B,KCNAB1,NLRP3" Drug 3934_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALCAM,ADAM15,GYG2,LDLRAD4,B4GALT6,CNTFR,AKAP7,RCHY1,CSF1,RIMS2,TBC1D5,TOM1,HIPK3,FHL1,KHDRBS3,USP19,GNG4,GRIK5,DHX35,KCNJ5,MAP4,PFKFB2,ZDHHC14,RGS12,SEMA6D,SH3BP2,FERMT1,NLGN1,FAM214B,MAPKBP1,KDM4B,SPTAN1,PHLDB1,EXOC7,TRIO,VAV1,SPHK2,SLC17A7,KCNAB1" Drug 5435_DN Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASPHD1,AK2,CLGN,SRSF11,B4GALT6,TPP1,QKI,AKAP12,FAM169A,DBT,VPS13B,DENND4A,FGFR1,FHL1,TRAF3IP2,GPD2,ELOVL5,HNMT,DHX35,INPP5B,KPNA5,KITLG,NF1,SLC25A23,FUZ,AMBRA1,PPP4R3A,ZKSCAN3,SPART,PLCB1,MTCL1,EXOC7,PCDHA6,SLC44A1,SPHK2,EVI5,GDPD5,SEMA3B,KAT6A" Drug 2641_UP Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "RALGAPA1,ADCY6,SYT13,KCNAB2,PLA2G4C,BAIAP3,CA4,CAMK2B,RUNX1T1,ARHGEF1,TAOK2,VCAN,PDE4DIP,RIMS2,KIAA0586,DBT,JAKMIP2,PLXNC1,HSD17B14,FGFR1,PRELID3A,SIGLEC8,INPP5K,GRM8,GSTM5,IL6ST,MGAT3,ADAM22,NOVA1,PLCD1,ZSCAN2,FAT4,ZMAT4,RGS12,FRMPD1,ZC3H13,TCF4,TRIM2,DOCK9" Drug 5098_UP Sulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "TRMT9B,N4BP2L1,MYOM1,LDLRAD4,CHGB,CHRNA4,CABP1,CSF1,RIMS2,MFAP3L,HS3ST2,TOM1,AASS,SRPK3,MTSS1L,FAM198B,ST3GAL6,TRAF3IP2,SEPT9,GNAO1,PADI2,HNMT,KIT,AFDN,MYO7A,NF1,NNAT,NPR2,PDE4B,POU6F1,KLHL11,FRMPD1,ASAP3,MAST1,TSNAXIP1,PCDHA5,VIPR2,ADAMTS9,KCNAB1" Drug 1774_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; HL60; HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ARRB2,CDK13,SLC4A4,MYRF,RUNX1T1,CLDN10,EPS15L1,SEC31B,PPP1R16B,PPP6R2,ARHGAP32,IGSF6,EZH1,IQCG,LILRA2,CACFD1,ICA1,LAMP2,GIT1,PTOV1,NINJ2,OGG1,PALM,PLEC,MAPK3,PTPRO,RGS3,RGS12,RXRA,ATXN7,ARHGEF40,ELMO2,KDM4B,UNC5B,THSD1,TBL1X,VIPR2,LAT2,ST7" Drug 3256_DN "Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AK2,ALCAM,GAS7,FAM131A,APOC1,ARRB1,SLC4A4,ADAM15,SYNJ2,PLEKHB1,TPP1,NECTIN3,SH2B1,SOCS5,PPP6R2,DCAF4,DAPK3,ARMCX2,EGFR,IRAK4,ING4,OGA,TXNL4A,SPACA9,GSN,ELOVL5,LYRM9,CNOT4,RPS6KA2,EMID1,SH3BP2,FUZ,SIRT2,ELMO2,BTBD7,REEP1,FTSJ1,EMSY,EPM2A" Drug 4318_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AK2,C1QTNF3,PKP4,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,FOXN3,AKAP5,CRY2,IRAK4,ETV1,FGFR1,SCARA3,TMEM8B,POLL,CACFD1,ICA1,IL6ST,LYRM9,CNOT4,NTRK2,GPR85,SNRK,C1orf54,COA1,TSNAXIP1,ARHGAP26,SPTB,ZBTB43,LHPP,EXOC7,PCDHA5,SLC44A1,TK2,R3HDM1,VIPR2,SPHK2,KCNAB1" Drug 2553_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "C1QTNF1,SRPX,BIN1,CFAP410,CALB1,THSD7A,STOML1,ABCG2,NRG2,RGS6,CSNK1E,MFAP3L,KLHL3,HS3ST2,EDN3,OPTN,ERBB2,CDKL3,GAD1,SIGLEC8,ADAM28,PCDH17,PRDM5,GUCY1B1,TAGLN3,NNAT,PLCD1,PPARA,PKNOX2,IZUMO4,ATP10B,TROVE2,ARC,SYT1,SYT5,ICAM5,TRO,KCNK12,KCNAB1" Drug 7546_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ACTN1,AP2A2,CDK10,MARCH3,ATP2B2,ARHGEF2,PLEKHB1,SULT4A1,HOMER3,DCAF4,PARD6A,SPOCK3,EGFR,RGS17,CGREF1,SIGLEC8,INPP5K,GLYR1,STON1,IL12A,NF1,CNTLN,RGS3,CCDC25,RPS6KA2,ZFP30,SH3BP2,AMBRA1,ARHGEF9,ZEB1,TPM2,RUNDC3B,UGT8,ZNF711,ZNF74,UPF3A,NAV3,EPM2A,ACTR3B" Drug 6203_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SEMA6A,BIN1,APBB2,CDC14B,SLC4A4,BMP7,CACNA1I,SEPT7,CDO1,ASIC3,SULT4A1,CNTFR,WHRN,CSF1,ECM2,EDNRB,VPS13B,RASGRP2,ERBB4,AGAP2,PCLO,MPP2,PCSK1,CCSER2,RETREG1,MARCH1,STUM,SH3BP2,FRMPD1,FAM214B,SS18,TCF4,DMXL2,DICER1,CHST8,SLC44A1,TK2,TUBB1,PRDM10" Drug 4610_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "GAS7,RGS11,SLC16A4,RGS6,ARHGEF10,GREB1,HS3ST2,DTNA,EDN3,FAM198B,CORO2B,ZMYND10,AGAP2,GNAL,GNAO1,PRUNE2,HNMT,IL6ST,MBNL1,MYCN,MYO7A,NEFM,NF1,PIK3R1,STRN3,PRKAR1B,RASGRF1,GAL3ST4,TCP11L1,ANKRD6,SLC8A1,DDN,SYT5,KLHL4,PCDHGB6,OBSL1,PCDHA6,DNAH7,VGF" Drug 5685_DN Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "BRAP,EIF4G3,RIPK1,KIF1A,CFLAR,HIP1R,PLEKHB1,SLC4A8,BAG4,ABCG1,PDE4DIP,DZIP3,INTS1,FECH,BAIAP2,TRAF3IP2,GLYR1,CNTRL,RNFT2,INPP5B,MAP4,ADAM22,MINDY2,KLK6,RIPOR1,RAD51D,AMBRA1,FBXO11,SPTAN1,ZBTB43,EXOC7,TRIM2,AP4E1,HIRA,UBTF,LMF1,MAP3K12,HPS4,KAT6A" Drug 4803_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SYN3,BEGAIN,APAF1,APC,PPP4R4,RASL11B,ATP6V0A1,CFAP410,CACNB4,CALB1,CALB2,CBFA2T2,ARHGAP33,VCAN,RIMS2,ZNF337,GIT2,RASGRP2,PTK2B,CORO2B,KAT8,IQCG,POLL,GRB10,PALM,PDE4B,PLCD1,PPP5C,PTPRB,PTPRE,KCNIP1,SH3BP2,FNDC3A,SLC6A8,SNCA,SYN2,TRIM2,TNS1,SSBP2" Drug 3117_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "OSBPL1A,ALK,CDC42BPA,CAPN3,HIP1R,CHN2,CREM,PDE4DIP,ARHGEF4,MFAP3L,CDON,HEYL,VPS13B,ETV1,DLC1,FGFR1,IQCG,ERAP1,GCNT2,ZNF276,GPD2,ADAMTS13,GRIK5,PADI2,KCNN1,KCNN3,NRCAM,PDE1C,POU6F1,PPP2R2B,PRKAR1B,GAL3ST4,MRAS,PEX26,CXXC4,SNCA,IZUMO4,TAL1,TUBB1" Drug 3230_DN Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ADRA1D,BIN1,CDC42BPA,FAM131A,ARRB1,RGS20,MARCH3,CFLAR,SYNJ2,SPAG9,USP2,CRLF1,SOCS6,LHX2,EPS15L1,CREM,PDE4DIP,CDON,TOM1,EDNRA,CNNM1,HSD17B14,MTSS1L,SEMA4D,KCNQ3,MGAT3,MITF,MAPK7,EMID1,NLGN1,TSPYL2,PIK3R5,ZKSCAN5,PLPPR2,VIPR2,REEP1,TIGD6,GAN" Drug 3937_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ARHGDIG,ADAM23,ADGRB3,HAP1,SLC16A4,KCNAB3,CDO1,RAB33A,LY86,WHRN,DCAF4,HIPK3,ELN,ETV1,PTK2B,ZNF589,FHL1,AFF2,AP4S1,ICA1,IGF1,LIFR,TM6SF1,KITLG,NTRK2,CEP41,KLHL11,SCN8A,STUM,RASA3,FBXO11,ST6GAL1,HECW1,ATP10B,TCF4,DMXL2,HIF3A,KCNAB1,DPF3" Drug 2103_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ABHD6,LGR5,LARGE1,ABCG2,CPS1,FAM169A,SLITRK5,DAPK3,PLXNC1,ANKMY1,FGF1,TRAF3IP2,SEPT9,GLYR1,FERMT2,CACFD1,BACH2,ICA1,MEIS1,MMP16,MYO7A,SERPINI1,FAT4,ZCWPW1,FBXW7,SCN8A,DZIP1,ZKSCAN3,ZHX3,IQSEC2,ZBTB43,DDN,SAMSN1,PRRC2C,ASTN2,IQCE,TK2,ZBTB14,MAP3K12" Drug 2401_UP Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA1,MTUS1,C1QTNF1,C1QTNF3,TRMT9B,BCAS1,ZSCAN18,ATP2A2,ATP2B2,CFAP410,LARGE1,CSNK1E,DCAF4,DOCK4,DBT,GSDME,DMPK,FAM13A,EIF1,MTSS1L,AFF2,SIGLEC8,ATXN2L,ITGAM,SCAMP5,PDE1B,PPP5C,KLK6,PTPRD,RGS3,GALNT10,MRAS,SH3BP2,EPN2,FAM214B,IZUMO4,FLRT2,ZBTB38,PCBP4" Drug 4709_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APBB2,BMP7,GYG2,ARHGAP33,SOCS6,TPP1,COL4A5,CRY2,CSNK1E,SIPA1L1,SOCS5,PDE4DIP,PPP6R2,OPTN,HSD17B14,ENO2,COQ7,SCML2,ST3GAL6,BAIAP2,FYN,TRAF3IP2,SYT17,GNG4,TDRKH,KPNA5,MIA2,NF1,OGG1,PTPRE,MAPKBP1,LHPP,ZEB1,SLC44A1,THRA,TK2,ZKSCAN5,FAM155A,VGF" Drug 3115_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SPARCL1,AMPH,LGR5,SLC2A11,ADAM23,FUBP1,CA12,HIP1R,SCARB1,SEPT7,EPS15L1,PLAA,PDE4DIP,RIMS2,DAPK3,CDON,E2F5,RASGRP2,ETV1,KHDRBS3,SIGLEC8,SRCAP,ADAM28,POLL,GPD2,GUCY1A1,AFDN,MPP2,NTRK2,VPS13C,PTPRN,RASGRF1,ASAP3,ABLIM3,HECW1,SS18,SEPT8,MCF2L,SLC17A7" Drug 5507_DN Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APC,MARK4,SLC4A4,SCAPER,KYAT1,AP4M1,TAOK2,NECTIN3,PDE4DIP,ZNF337,DMPK,CDON,ERBB2,DLC1,FHL1,GAA,ZNF276,CRCP,MSL3,SPACA9,ITPKB,KCNF1,LMO2,MITF,MPP2,NF1,MBOAT7,NKAIN1,RAD51D,ZCWPW1,FBXW7,FUZ,PREX2,PPP4R3A,LIMCH1,MAPKBP1,KDM4B,ST7,RNF170" Drug 2630_UP Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "APAF1,KCNAB2,PLA2G4C,GYG2,CA4,CAMK2B,ARHGEF1,SCARB1,CHN2,LY86,LRIG1,ARHGEF10,PYGO1,INTS1,DAPK3,SPOCK3,DTNA,FGFR1,GALC,SIGLEC8,INPP5K,ALDH1L1,MALT1,GLYR1,GPD1,LMO2,NPR2,PURG,C1orf54,RGS12,FBXW7,KDM4C,IQSEC2,TAL1,TBCEL,TNS1,ZKSCAN5,SLC30A3,NT5M" Drug 3686_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASPHD1,NDRG2,NME5,PPP4R4,ATP2A2,ATP6V0A1,ADAM23,GYG2,CFAP410,USP2,MAGI1,AATK,CYBB,SHANK1,EGFR,GATM,ALDH1L1,GFER,PRUNE2,ICA1,IL12A,MARK1,MMP16,PNMA3,ZSCAN32,RFX2,SALL1,HKDC1,NFASC,PCDHGA10,DOCK9,RIMBP2,TRIO,TRO,UCHL1,OSBP2,TRIM9,MKRN3,KCNAB1" Drug 3120_UP Esculetin [305-01-1]; Up 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD2,CDC42BPA,GYG2,CA12,CACNA2D1,CAST,AP4M1,ARHGAP33,DCAF4,BRINP1,TMCC2,EDNRB,HEYL,CELSR3,RASGRP2,ETV1,ANKMY1,F5,PRELID3A,GFER,GRIK5,HNMT,ICA1,ITPKA,KCNQ3,MAP4,CNOT4,NPTX1,PLCD1,LRRN3,BCAS3,MTMR10,FAM184A,CLIP1,GALNT10,SLC11A1,DOP1A,ZSWIM8,PRDM10" Drug 4732_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG2,TRMT9B,GAS7,ATP6V0A1,CAMK2G,B4GALT6,TAOK2,SLC4A8,SOCS5,ARHGEF4,DOCK4,DBT,PARD6A,IRAK4,ACSL4,SCML2,FHL1,COPS8,GLYR1,RASSF8,IL6ST,KITLG,MID1,NF1,NFYA,PDE4A,RETREG1,SAMD9,ELOVL2,FNDC3A,FAM214B,BTBD7,SMARCD3,FBXW11,DMXL2,TMEM121,THRA,HIRA,ZBTB14" Drug 1526_DN Midecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASPHD1,APBB2,APOC1,SLC4A4,KYAT1,CBFA2T2,CRLF1,SULT4A1,ABCG1,CSNK1E,DZIP3,TMCC2,EGFR,MBNL2,ANKMY1,EZH1,NOP56,GLYR1,SLC2A6,KCNH2,MAP4,NF1,NFYA,CCSER2,TCP11L1,ZNF821,BTBD7,ZKSCAN3,PLCB1,ARC,FBXW11,KIAA0930,TNS2,AP4E1,RPRM,UBTF,VGF,ZNF23,PHTF2" Drug 7138_DN Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AK2,MADD,NCOA1,PTBP2,CDC42BPB,DCAF4,ARHGAP32,GIT2,DBN1,C2CD2L,RHOBTB1,PARD6A,FEM1B,SUGP2,RACK1,FGFR1,PDLIM5,CAMKK2,CELF1,FERMT2,SLC2A6,IL6ST,FAM69A,NF1,NOVA1,PIK3R1,POLG,RIPOR1,ROGDI,SUGCT,ATXN7,EPN2,CAMTA2,RGL1,VPS13A,EXOC7,SATB2,TK2,SSBP2" Drug 6322_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ADCY6,BIN1,PDE8B,CACNA2D1,HAP1,CACNA2D2,NCOR1,ARHGEF4,HDAC9,RUSC2,EDNRA,ETV1,ST3GAL6,BAIAP2,AGAP2,TRMO,TMEM8B,NEU3,CACFD1,SYNPO,MAPT,MGAT3,ADAM22,MT1M,MX1,PFKFB2,PIK3R1,CCSER2,BCAS3,SNRK,PTCH1,PTPRE,SCN8A,SLC9A5,CDK5RAP2,HIRA,EVI5,MARCH8" Drug 4559_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SLC4A4,KSR1,CACNA1I,IL33,B4GALT6,LY86,VCAN,CNTNAP2,C2CD2L,CDON,ING4,TNK2,RASGRP2,FLT1,FYB1,GFER,GRM8,GSTM5,JAK2,KCNJ5,NPR2,NPTX1,PTPRH,KHDRBS2,CCDC102B,KCNIP1,ZFP2,MRAS,RASA3,PKNOX2,SLC11A1,SLC12A4,SNCA,TSNAXIP1,NFASC,ZEB1,TPM2,EVI5,SENP7" Drug 6665_UP Famotidine [76824-35-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SPARCL1,BMPR1B,BAIAP3,KALRN,HAP1,CAMK2A,CBFA2T2,FAM149A,CSF1,ARHGEF10,INTS1,DAPK3,C2CD2L,HIPK3,MTSS1L,APC2,OLFM1,ZNF44,SIGLEC8,CSDC2,GLI2,GNAL,SPACA9,KCNJ5,KITLG,ADAM22,ENPP2,PFKFB2,PFKFB4,RETREG1,POU6F1,LRRN3,KIRREL1,HECW1,TIMP4,TPM2,ZNF74,SLC30A4,JPH3" Drug 6237_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AP2A2,BCAS1,PDE8B,DNAH17,RGS11,ARHGEF1,CHN2,CLCN3,VAX2,COL9A3,PDE4DIP,SPOCK2,FECH,FGF12,FHL1,EFCAB2,ERAP1,GRM8,MAP4K5,KHK,LRRN3,SAMD9,KHDRBS2,RNASEL,ZNF821,MRAS,FAM214B,MAPKBP1,SNCA,PHLDB1,ASTN2,WSCD1,KIAA0930,TNS2,UBTF,REEP1,EMSY,ADAMTS9,SEMA3B" Drug 6180_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA1,MTUS1,TRMT9B,APBB2,CDC14B,CDK10,PDE8B,BCL7A,BMP7,SLC16A4,TAOK2,CLTB,NRG2,DGKG,MRNIP,VPS13B,RASGRP2,PIPOX,KCNJ5,MAP2,MID1,AFDN,NELL2,NTRK2,OPRL1,PTPRN,SEMA6D,SH3BGR,PEX26,SLC8A1,EXOC7,TCF4,SYNE1,CHST8,ICAM5,HIRA,LMF1,SLC17A7,KCNAB1" Drug 5747_DN Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,AP2A2,CDC14B,ADAM15,SCAPER,FOXN3,ASIC3,B4GALT6,RAB28,CRY2,CSNK1E,SLITRK5,GIT2,CDON,EIF4G2,FGFR1,CGREF1,TRAF3IP2,GNG4,MUM1,HSF2,L1CAM,SCAMP5,RETREG1,PTPRN2,PID1,RAD51D,ZNF671,MAPK12,SBF1,SNCA,KDM4C,PHLDB1,KIAA0930,CHST8,VGF,ZNF32,NAV3,MPPE1" Drug 5016_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALCAM,CDC14B,MARK4,SLC16A4,CRLF1,CACNA2D2,SOCS6,CNTNAP2,DBT,PARD6A,EXOG,DMPK,EDN1,CDKL3,FGFR1,OGA,SRCAP,IRAK3,IL6ST,KCNH2,KIF5A,KITLG,ADAM22,PRKAR1B,MAPK10,RAD51D,ZFHX4,SMARCD3,LIMCH1,DOK5,ZC3H13,CDK19,RBM26,SZT2,PARD3,HIRA,UCHL1,ZFP37,SEMA3B" Drug 5525_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ABHD6,MTUS1,OGT,APOC1,SOCS6,ARMC8,COL4A5,NECTIN3,AKAP12,CSNK1E,PDE4DIP,PPP6R2,GIT2,DPH1,EGFR,POLR1B,FHL1,TRAF3IP2,DISC1,KCNF1,LMO2,MAPT,MSI1,NF1,OCRL,PDE4A,ZCWPW1,RGS12,SBF1,NUBPL,PPP4R3A,EPN2,TROVE2,TACC1,CHST8,TPM1,ZBTB14,FTSJ1,SMIM8" Drug 6131_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "EPB41L5,SLC4A4,NRP2,SYNJ2,CFAP410,CACNA2D1,CDH2,TAOK2,SLIT2,CREM,DCAF4,SPOCK2,PARD6A,MTSS1L,STX2,ERBB2,ETV1,F5,FGF1,POLL,STON1,HLF,ICA1,KCNJ5,NTRK2,PDE4D,PFKFB4,MINDY2,CARF,KCNIP1,PKNOX2,TMCC1,SPTAN1,TBCEL,TCF4,TRIM2,KCNE5,MKRN3,SPHK2" Drug 6578_UP PHA-00665752 [477575-56-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALCAM,AMH,AMPD3,APLP1,PPFIA3,CDK10,MARK4,ALDH7A1,CFAP410,CA4,CA12,KYAT1,SOCS6,HSD17B14,CDKL3,FGFR1,FAM49B,PRELID3A,SIGLEC8,DISC1,MSL3,GRB10,SLC2A6,INPP1,NPR2,PCDH9,RAD51D,PPP4R3A,OGDHL,SPTAN1,ST5,ELOVL4,TTBK2,TNS2,SIK3,SLC44A1,ZKSCAN5,UPF3A,MAP3K12" Drug 1240_DN 2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "CDC42BPA,APAF1,ARHGEF7,FUBP1,MTMR3,HOMER3,CDC42BPB,CREM,HINFP,DZIP3,PPP6R2,DCAF8,TM9SF4,ZNF804A,EDN1,COQ7,FGF1,BAIAP2,TRMO,ATP2C1,PRRC2B,MUM1,DHX35,MATN3,NDP,PDE4B,CCSER2,STRN3,KIRREL1,SH3BP2,AMBRA1,LIMCH1,SNCA,STX1A,CHST8,CBX5,PARD3,UPF3A,SENP7" Drug 6585_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADCY6,BIN1,APC,GAS7,ADAM23,BID,HOMER3,ENTPD4,ABCG1,SIPA1L1,DCAF8,MAML1,DAPK3,GIT2,DMPK,DUSP9,APH1A,STX2,FGF1,INPP5K,GFER,SLC2A6,DHX35,LYRM9,ZNF862,PLCD1,WDR47,FAM214B,BTBD7,COA1,CDK5RAP2,ZBTB43,EXOC7,TNS1,XRCC4,REEP1,SEMA3B,NAV3,MPPE1" Drug 2380_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "BEGAIN,SPTBN4,ARRB2,PDE8B,ADAM23,USP2,SEPT7,TPP1,ENTPD4,CRMP1,DGKG,GSDME,PIPOX,RRAGB,FHL1,HPCAL4,EFCAB2,PDLIM5,KHDRBS3,SIGLEC8,INPP5K,ICA1,KCNF1,KHK,SCAMP5,NFIX,NRCAM,CCSER2,MINDY2,CNNM2,GALNT10,SNCA,RBM34,RBM26,ATP10B,CRTC1,PCDHA5,SLC35G2,SLC17A7" Drug 3277_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AP2A2,APC,GAS7,FAM131A,ARRB1,ST3GAL5,QKI,SLC4A8,LRIG1,FBXL5,DMPK,EGFR,EIF5,HSD17B14,EZH1,FER,OGA,TXNL4A,GPR37,SPACA9,MAP4,GIT1,NF1,NPTX1,PTCH1,RGS12,EMID1,SBF1,SMARCD3,KDM4C,CLASP2,PLCB1,TNS2,SLC44A1,VGF,REEP1,EMSY,HPS4,MPPE1" Drug 2664_UP "aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "MTUS1,APAF1,PPFIA3,PPP4R4,CASK,SCARB1,RAB33A,SLC4A8,CREM,CNTNAP2,DZIP3,USP6NL,ZNF337,DAPK3,HIPK3,RRAGB,FGFR1,FHL1,PDLIM5,PRELID3A,GALC,ALDH1L1,LILRA2,STON1,GRIK5,SYNPO,IL6ST,NPTX1,OXTR,PPARA,CRTAC1,EMID1,RPS20,TMCC1,TACR1,CUX2,TRPS1,PRDM10,SLC17A7" Drug 314_UP sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "KDM5D,ADD2,LTBP4,OGT,GAS7,CHRD,AZGP1,BAIAP3,CFAP410,CAMK2A,B4GALT6,VCAN,PDE4DIP,ING4,ELN,COQ7,STX2,NCALD,SPEG,TRMO,RUNDC3A,GUCY1A1,ITPKB,KHK,NEK1,P2RX7,FXYD1,STRN3,PTPRD,SUSD4,ATXN2,FRMPD1,ABLIM3,KDM4B,NMNAT2,ADGRL3,GPR161,FLRT2,ZIC1" Drug 7174_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ADCY6,ADORA1,AK2,FAM131A,BACH1,MPDZ,CFLAR,SCAPER,BAIAP3,CA12,SCARB1,ARHGEF2,RCHY1,PDE4DIP,SPOCK2,PARD6A,CDON,DTNA,EGFR,EGR3,CDKL3,ANKMY1,FGFR1,FAM49B,SRCAP,TXNL4A,GLYR1,LIG4,MMP16,PAX6,RGS12,TCP11L1,SBF1,PPP4R3A,COA1,TSPYL2,TK2,TIGD6" Drug 5415_DN Vigabatrin [60643-86-9]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "DNAH17,ALDH7A1,SCAPER,HAP1,SLIT2,DBN1,DTNA,EPB41L2,NCALD,FGFR1,SEPT9,GCNT2,GRIK5,CACFD1,ATXN2L,LSS,MAP4,MGAT3,ADAM22,ZNF862,CNOT4,SAMD9,NKAIN1,RGS12,EPN2,FAM214B,ZSWIM8,UNC5B,ST5,TTBK2,JMJD6,PLCB1,MCF2L,TNS2,PCDHA6,VGF,VLDLR,ZNF45,GDPD5" Drug 7314_DN Nifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "MTUS1,CDC42BPA,APAF1,PPFIA3,SCAPER,PLAA,BAG4,CPS1,NCOR2,GPRASP1,DCAF8,FEM1B,TENM1,RGS17,FCGRT,FECH,PDLIM5,SEPT9,CNTRL,MUM1,FAM69A,KIF2A,ZNF426,PTPRE,FBXW7,SUPT20H,ASAP3,SMARCD3,LIMCH1,NXT2,IQCE,TMPO,TRIO,ZKSCAN5,HIRA,NDRG4,SPHK2,TFIP11,PCBP4" Drug 3355_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "DOC2A,APLP1,APOC1,PDE8B,MTMR3,GYG2,CA4,CBFA2T2,RAB28,WHRN,ENTPD4,CRY2,DCAF4,DTNA,HSD17B14,SEMA4D,SYT17,SRCAP,ZNF276,CNTRL,CACFD1,MIA2,ADAM22,CDK18,SLC25A23,RPS6KA2,ZNF821,SH3BP2,EPN2,SLC6A8,IQSEC2,TROVE2,THSD1,ST5,FBXW11,SLC44A1,WIPF1,XRCC4,ST7" Drug 2629_DN Bepridil hydrochloride [74764-40-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AK2,BIN1,OGT,APBB2,MTMR2,CFAP410,KYAT1,SCARB1,PPP6R2,DCAF8,MAMLD1,CNNM1,IRAK4,KAT8,FHL1,GPER1,RNFT2,JAK2,KIF2A,MAP4,NF1,SETD4,PRKACB,RAD51D,RGS3,RNASEL,NEK11,FBXW7,TCP11L1,FERMT1,TMCC1,CLASP2,CEP68,TMPO,TPM1,UBTF,VGF,EMSY,RNF170" Drug 2353_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AP2A2,AMPD2,BIN1,RGS9,SYNJ2,IQCK,SEC31B,CRMP1,ARHGEF4,DNM1,RCAN1,COQ7,MTSS1L,ERBB2,SIGLEC8,SPIN1,KCNMB4,INPP5B,MAP4,MGAT3,NF1,SLC25A23,PTPRB,TMEM231,GAL3ST4,PNMA8A,SH3BP2,PKNOX2,SNCA,KDM4B,ZSWIM8,DBNDD2,SPTAN1,PDLIM2,TBCEL,TBL1X,KAT6B,ZBTB38,KAT6A" Drug 4726_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AP2A2,DOC2A,MARK4,ALDH7A1,ADAM23,CA12,CAMK2G,TAOK2,NECTIN3,NCOR2,ARHGEF4,PPP6R2,KIAA0586,BRINP1,MFAP3L,DMPK,AASS,SEMA4D,CGREF1,FYB1,GAD1,GFER,GNG4,MUM1,ZNF862,NF1,SLC11A2,LRP12,PPARA,MAPK7,RIPOR1,SPTAN1,EXOC7,SMG6,ZEB1,FAM155A,VIPR2,KCNK12,REEP1" Drug 3687_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD2,ATP6V0A1,CAMK2B,CDO1,CHN2,SULT4A1,GPRASP1,EXOG,DTNA,EDN1,FGF1,SEMA4D,SIGLEC8,GNAL,NXPH3,HSF2,TJAP1,INPP5B,ITGA7,KCNF1,KCNJ5,LSS,ADAM22,NPY,PNMA3,NECAB2,RAD51D,RNASE1,STK32B,DOP1A,MCF2L,PCDHGA10,PCDHA5,TMPO,TNS1,FLRT2,ZNF225,EPM2A,NLRP3" Drug 7309_DN Hydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "C1QTNF1,APBB2,APOC1,PPFIA3,ARRB2,EIF4G3,CFLAR,STOML1,PARD6A,FEM1B,COQ7,FGFR1,ATP2C1,ERAP1,SEPT9,COPS8,CNTRL,IFI16,SHISAL1,MBD1,MITF,NF1,NFIX,PPP5C,BCAS3,CSRNP3,ASAP3,FAM214B,ZBTB43,CAMTA2,PDLIM2,R3HDM1,TSN,NDRG4,MAP3K12,EVI5,HPS4,NAV3,URM1" Drug 3798_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "AMPD3,SEMA7A,ATP1A3,NRP2,PLEKHB1,QKI,AKAP5,RIMS2,GIT2,MFAP3L,PARD6A,DTNA,EDIL3,ING4,ETV1,IQCG,OGA,TDRKH,ITGA7,KPNA5,MARK1,SCAMP5,LYRM9,NF1,CNOT4,NEK11,ZNF821,BTBD7,SNCA,IQCE,TRIM2,TRIO,LMF1,ZNF24,EVI5,KCNAB1,KAT6A,PHTF2,DPF3" Drug 3615_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG3,LTBP4,BIN1,EPB41L5,PPP4R4,ADAM15,CLGN,SLIT2,RCHY1,MFAP3L,DTNA,DUSP9,FAM198B,DISC1,GPD2,CNTRL,GSN,ELOVL5,SERPINI1,NLE1,FSD1,PRPH,ZSCAN2,ZDHHC14,TCP11L1,ZKSCAN3,KDM4C,ZC3H13,SPTAN1,LHPP,ST5,RGL1,TBCEL,FLRT2,LMF1,ZBTB14,GDPD5,ITM2C,KAT6A" Drug 601_DN MK-886; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ACTN1,SRPX,BIN1,AMT,CDC42BPA,ANK2,APC,ARNTL,PDE8B,MARCH3,BMP7,CDH2,ENTPD4,ARHGEF4,GIT2,DPH1,RCAN1,FGFR1,MALT1,ADAMTS6,KIFC3,MAP2,MYT1,PIK3R1,STRN3,MINDY2,PPP2R2B,RELN,RNASE1,SBF1,ZNF821,FAM214B,SMARCC2,COBL,TNS2,CRTC1,ZNF34,PARD3,RPRM" Drug 3513_UP Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ALK,BIN1,APBA2,APBB2,SCAPER,HAP1,CAMK2B,CACNA2D2,TAOK2,TPP1,FAM149A,ENTPD4,DTNA,PLXNC1,TNK2,ERBB2,NRN1,EFCAB2,FAM49B,NXPH3,ICA1,KIT,AFDN,NELL2,PDE1C,LRP12,MINDY2,MAPK10,SAMD9,SNRK,C1orf54,RPS6KA2,SYBU,ZC3H13,SPTB,ATP10B,VIPR2,WIPF1,GDPD5" Drug 4198_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "BIN1,GAS7,PPP4R4,ZSCAN18,BCHE,NRP2,SCAPER,SCARB1,SYNGR3,ARHGAP33,MAGI1,ASIC3,AKAP5,DTNA,EDIL3,HIPK3,FRY,CORO2B,ZNF589,OLFM1,CSPG5,DISC1,ITPKA,SMAD1,ADAM22,NF1,P2RY1,NLE1,PTCH1,ZSCAN32,RFX2,PNMA8A,TCP11L1,SEMA6D,SLC8A1,THSD1,PCDHA5,FLRT2,WIPF1" Drug 5800_DN Rauwolscine hydrochloride [6211-32-1]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "C1QTNF3,MARK4,ST3GAL5,SYNJ2,ARHGEF2,VCAN,PDE4DIP,PPP6R2,ARHGAP24,RUSC2,C2CD2L,TMCC2,DPH1,HIPK3,CDKL3,ZNF589,FGF1,GNG4,MAPT,MIA2,ZNF862,NF1,NPR2,NTRK2,PCDH9,PLXNB1,MINDY2,PPP5C,MAPK7,PTPRH,SH3BP2,PREX2,ZNF667,SPTAN1,DDN,COBL,CRTC1,TPM2,KCNAB1" Drug 5885_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "RALGAPA1,ABCD2,PPP4R4,KIF1A,ST3GAL5,BAIAP3,DAPK3,MFAP3L,EGFR,HSD17B14,TUBD1,ZNF391,FGFR1,PDLIM5,TMEM8B,SEPT9,LILRB4,GRM8,BACH2,ELOVL5,SCIN,KCNB1,ADAM22,PLCD1,MINDY2,WDR25,PTPRB,PTPRN2,BTBD7,TMCC1,DOK5,NMNAT2,SYN2,TACR1,KIAA1107,TCF4,KIAA0930,SLC44A1,TIGD6" Drug 5999_DN (1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "CDC42BPA,PKP4,BCAS1,PDE8B,NUMB,SYNJ2,MTMR3,CBFA2T2,ARHGEF2,HOMER3,HINFP,GIT2,MFAP3L,ANKMY1,KAT8,CINP,ATP2C1,SEPT9,MALT1,MSL3,ITPKB,KHK,MAP4,ZNF862,NEK1,LRP12,TMEM231,CCDC25,TRAPPC13,KIF16B,ZHX3,TTBK2,PLCB1,PCDHA5,TMEM121,TPM1,HIRA,GDPD5,KAT6A" Drug 6940_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ADD2,ALK,APBB2,ARHGDIG,CFLAR,CAMK2B,CCNT1,SCARB1,CRLF1,PLEKHB1,STOML1,WHRN,SLC4A8,CREM,DUSP9,EDNRA,OPTN,C3orf18,APC2,SEMA4D,INPP5K,POLL,PCLO,ITGA7,MIA2,ADAM22,NF1,GPR85,TMEM231,TCP11L1,SPTAN1,CLSTN2,ZNF302,TTBK2,ASTN2,IQCE,TK2,ZNF45" Drug 3184_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "PPFIA4,APAF1,CDC14B,ATP1A3,BACH1,ADGRB3,BCHE,HAP1,SLC16A4,CHN2,B4GALT6,CPS1,HAPLN1,NCOR2,CSF1,RASSF2,LYPD1,AASS,TNK2,FGFR1,HPGDS,ITGA7,KCNB1,NEFM,NOVA2,GPR85,PLTP,PPP1R1A,PPP5C,PRODH,DCHS2,GAL3ST4,MRAS,DOK5,TROVE2,ZEB1,SLC35G2,TRIO,UGT8" Drug 6043_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "LTBP4,AMT,CDC42BPA,ADAM23,BACH1,KSR1,HIP1R,CHN2,TAOK2,STOML1,MYRIP,RUSC2,HSD17B14,ERBB4,ACSL4,ZNF589,FGF1,BAIAP2,GAD1,SIGLEC8,GPR162,RUNDC3A,PRUNE2,CACFD1,HLF,SYNPO,KIT,C1orf54,RASGRF1,RGS4,RASA3,SLC9A5,CXXC4,MYH15,PHLDB1,GPR161,TNS1,UCHL1,KAT6A" Drug 3339_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADORA1,GAS7,CDK13,SLC4A4,ATP2A2,ADAM23,CFLAR,CACNA1I,LDLRAD4,CFAP410,SLC16A4,ARHGEF6,MBNL2,EPHB1,FAM198B,ACSL4,FHL1,DISC1,GPR37,NXPH3,ICA1,IL6R,NPR2,C19orf57,CNTLN,ACSM5,C1orf54,RASGRF1,TRIM68,RASA3,ASAP3,CCDC88A,COA1,OGDHL,ZC3H13,SPTB,GPR161,NT5M,EVI5" Drug 7348_DN Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,ALCAM,APLP1,MARK4,CFLAR,TAOK2,RAB28,ABCG1,KIAA0586,MFAP3L,C2CD2L,TMCC2,HSD17B14,ANKMY1,SCML2,FGFR1,SEMA4D,MSL3,GRB10,KCNH2,LMO2,MAP4,MATK,GIT1,ZNF862,NPR2,MBOAT7,PRPH,RGS12,GSTCD,EPN2,ZKSCAN3,SZT2,BHLHB9,BEX4,REEP1,ST7,UBE3B,SMIM8" Drug 3924_DN Solasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "LTBP4,APLP1,DNAH17,MARK4,CFAP410,RAB28,CNTN1,CPS1,CSF1R,MFAP3L,CDON,EDN1,FCF1,STX2,ERBB2,FAM198B,PRKAG2,FHL1,GAD1,SRCAP,GLYR1,CACFD1,DHX35,IL6ST,KCNN2,CDK18,SERPINI1,PRKAR1B,FBXW7,COA1,LHPP,ATP10B,THSD1,VPS13A,PLCB1,PCDHA6,TRIO,KCNK12,PHTF2" Drug 1560_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "NDRG2,BEGAIN,ARNTL,BMP7,SCAPER,HAP1,P2RX6,PICK1,SEC31B,ENTPD4,SLITRK5,KIAA0586,EPHB1,STX2,IGSF6,ANKMY1,TRMO,TPK1,TRAF3IP2,ADAMTS13,IL6R,NFYA,P2RX7,PDE4B,PLCD1,SLC25A23,POLR2F,RNH1,TCP11L1,SH3BP2,SLC11A1,ZC3H13,FAM208A,TCF4,OBSL1,KAT6B,TRPS1,CA14,GORASP1" Drug 3681_UP Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "SEMA7A,ATP2B2,CACNA1I,CFAP410,CHN2,CHRNA4,CSF1R,ARHGAP24,ARMCX2,SV2B,FCF1,RGS17,IGSF6,F5,SEMA4D,GABRB3,GRM2,KCNH2,KCNJ5,KIFC3,LAMA2,NELL2,NF1,MINDY2,PTN,PTPRD,HKDC1,DDN,ATP10B,SYT1,CRTC1,TNS1,LAT2,SPHK2,ZNF154,LAMP5,SEMA3B,KCNAB1,NLRP3" Drug 6361_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "DOC2A,AMT,SEMA7A,CDC14B,PPP4R4,ARRB2,CFLAR,BMP7,BAIAP3,ZMYM4,ABCG2,WHRN,AATK,SLITRK5,ARHGAP24,FAM13A,FGF1,SCARA3,FYB1,ERAP1,GPER1,RASSF8,AFF1,NRCAM,PALM,PTPRN2,TMEM231,GAL3ST4,SCN8A,STUM,SNCA,KIF13A,KDM4C,CEP68,ARC,KIAA1107,TK2,VGF,XRCC4" Drug 1809_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD1,BRAP,KCNAB2,APOC1,PPFIA3,MARK4,HOMER3,CSF1,RUSC2,SCML2,SCARA3,PDLIM5,SYT17,DISC1,INPP5K,SRCAP,USP19,TXNL4A,SLC2A6,DHX35,SHISAL1,KIF2A,KIFC3,MPP2,GIT1,MX1,OGG1,PFKFB2,KCTD15,MAPK12,FAM214B,SS18,EXOC7,IQCE,WSCD1,BHLHB9,LMF1,ZNF32,SMIM8" Drug 3925_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "KDM5D,ADRA1D,AGT,C1QTNF1,AMH,MARK4,ATP1A3,SYNJ2,GYG2,CACNA1I,CAMK2B,CDH2,NCOR2,OSBPL3,GSDME,TNK2,ERCC2,APC2,ETV1,GAD1,POLL,GPR12,IFI16,ITGA7,MSI1,GAL3ST4,KCNIP1,FRMPD1,ST6GAL1,PKNOX2,FAIM2,NMNAT2,SMG6,TK2,TNS1,TRO,LAT2,XRCC4,KCNAB1" Drug 2061_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ASIC1,LTBP4,APOC1,PDE8B,SLC4A4,NRP2,MYRF,PLEKHB1,CNOT8,CSF1R,DTNB,CNNM1,MTSS1L,FGFR1,IQCG,PDLIM5,DLL3,ZNF44,GFER,GLI2,GLYR1,STON1,CACFD1,TJAP1,SCIN,ITGAM,MMP16,GIT1,NFIX,NNAT,NLE1,PLXNB1,WDR25,ELOVL2,RET,ZFP30,IFT122,DDN,DPF3" Drug 2384_UP Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "ADD2,CASK,ARRB1,ARRB2,ZSCAN18,KYAT1,HOMER3,RIPOR2,GSDME,MRNIP,RRAGB,PRELID3A,SIGLEC8,INPP5K,GPD2,LILRA2,ICA1,ITGAM,MAPT,ZNF862,NPR2,PDE1C,PDE4A,PDE4D,CCSER2,MINDY2,PPP5C,MASP1,RASA3,KDM4B,KDM4C,SS18,STX1A,PDLIM2,ZNF34,SSBP2,REEP1,MAP3K12,KCNAB1" Drug 4222_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-04 1.00E+00 3.92E-03 4.42E-02 39 197 "FUBP1,DLGAP1,CBARP,CHN2,CHRNA4,NRXN3,TPP1,RAB26,CSF1,DTNA,EDN3,ERBB4,AFF2,EFCAB2,SIGLEC8,SRCAP,GFER,CSDC2,STMN2,ADAM22,PCSK5,PTPRN2,RASGRF1,TCP11L1,ASAP3,SLC4A3,PREX2,PKNOX2,CXXC4,IZUMO4,SYP,ADGRL3,PHF24,THRA,TRIO,TRO,WIPF1,KCNK12,DNALI1" Drug 7074_UP MS-275; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.81E-04 1.00E+00 3.98E-03 4.49E-02 37 184 "MTUS1,ADGRF5,SLC4A4,ST3GAL5,SYNGR3,ABCG1,DZIP3,PLPPR4,RGS17,FGF13,FYB1,FYN,SYT17,GRB10,MAP2,MAPT,MEF2C,SCAMP5,MMP16,TAGLN3,PDE4B,ENPP2,SERPINI1,PMP22,PRPH,PTPRH,SH3TC2,RGS4,SYBU,SAMSN1,CEP68,RGL1,SYT1,TNS1,TRIM9,NAV3,PLSCR4" Drug 5530_UP Parthenolide [20554-84-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.81E-04 1.00E+00 3.98E-03 4.49E-02 37 184 "APC,PPFIA3,CFLAR,SPAG9,CREM,DAPK3,MFAP3L,PLXNC1,LRRC17,RASGRP2,CDKL3,BAIAP2,AMOTL2,IP6K2,ATP2C1,SRCAP,SESN1,CACFD1,BTN2A1,IL6R,IL12A,LIG4,ZNF862,SERPINI1,SMIM7,NECAB2,C1orf54,SH3BP2,KDM3A,ZBTB43,JMJD6,R3HDM1,CA14,ZKSCAN5,UBE2H,ZNF45,RNF146" Drug 2185_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.81E-04 1.00E+00 3.98E-03 4.49E-02 37 184 "BIN1,LGR5,KSR1,BMP7,MTMR3,CACNA1I,LDLRAD4,PLAA,AATK,SIPA1L1,PDE4DIP,DCAF4,RIPOR2,FAM13A,ETV1,TBC1D16,KHDRBS3,ERAP1,ALDH1L1,LYVE1,GSN,IRAK3,KCNJ5,MBP,NF1,NRCAM,NTRK2,CLDN11,SLC25A23,MARCH1,RNASE1,ZNF821,FRMPD1,CPEB3,CLSTN2,SAMSN1,RPRM" Drug 5228_UP 15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.81E-04 1.00E+00 3.98E-03 4.49E-02 37 184 "NME5,BIN1,MARK4,BACH1,SYNJ2,GYG2,CACNA1A,HAP1,SLC16A4,ARHGEF2,CLGN,SOCS6,PLAA,CREM,CRY2,CTH,HIPK3,MBNL2,FECH,FGFR1,BAIAP2,IP6K2,GLYR1,POLL,IL6R,ADAM22,PLCD1,NECAB2,PPP5C,ROBO1,ZNF821,STX1A,WSCD1,TRIM2,UCHL1,VLDLR,ZFAND5" Drug 2946_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.81E-04 1.00E+00 3.98E-03 4.49E-02 37 184 "BIN1,APBB2,ST3GAL5,CD86,AP4M1,TPP1,CREM,ABCG1,SIPA1L1,VCAN,PPP1R16B,SPOCK2,FAM13A,PRELID3A,COPS8,PRUNE2,PADI2,HNMT,TJAP1,LSS,MEF2C,MIA2,NRCAM,PDE4B,CCSER2,RETREG1,PILRA,MAPK7,RXRA,SPTAN1,THSD1,SYT5,PDLIM2,SLC44A1,TNS1,TPM1,UBTF" Drug CID000444878 carboxymethyl-CoA Stitch 3.86E-04 1.00E+00 4.03E-03 4.54E-02 9 22 "ABHD6,CLTB,CS,DHRS4,PCSK1,PKM,PLCD1,SYNE2,NR2E1" Drug CID000003413 forskolin from Coleus forskohlii Stitch 3.89E-04 1.00E+00 4.06E-03 4.57E-02 150 1014 "ASIC1,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,AQP6,ARNTL,PDE8B,NCOA1,SLC4A4,SLC2A11,ALDH7A1,RGS9,HCN2,BMPR1B,CACNA2D1,CALM1,CAMK2B,CCK,KRIT1,USP2,LRBA,CHGB,ASIC3,CHRNA4,CLCN3,MYL6B,CNR1,AKAP7,AKAP6,AKAP5,CREM,CRHBP,HAPLN1,CSF1,PPP1R16B,PLCXD3,GPSM1,ARHGAP32,DAPK3,EDN1,EDN3,EDNRA,EDNRB,EGFR,RGS17,CALCRL,TUBD1,ERBB2,PTK2B,TUBB3,PPP1R1B,FGF1,FGFR1,FGFR3,CAMKK2,GABRA3,GABRB3,GABRG1,GABRG2,GALC,CPLX2,GCK,TUBA8,MSTN,GDF9,SESN1,PPARGC1A,CRCP,GNAO1,MCHR1,PLCD4,GRM2,GRM8,GUCY1B1,TNFAIP8L3,HMGCR,HP,MYLK2,IGF1,KCND2,AQP11,MBP,MITF,MMP16,MYO6,P2RY13,NF1,NPY,NPR2,OPRL1,OXTR,P2RY1,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ABCB1,PIK3C2A,PIK3R1,PLCB2,PLCD1,MBOAT7,PPP3CC,PRKACB,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTCH1,PTH1R,RET,RGS4,RYR3,MAPK12,SCN7A,FNDC3A,SLC12A2,SLC14A1,SST,SSTR1,SSTR2,PLCB1,ALG1,TBL1X,TK2,ACTR6,PIK3R5,CDK20,TUBB2A,TUBB1,VGF,VIPR2,VSNL1,P2RY12,SLC38A1,TUBA1A,PLD4" Drug 3855_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.00E-04 1.00E+00 4.17E-03 4.70E-02 38 191 "AP2A2,AMPD3,GAS7,APOC1,NRP2,BMP7,BAIAP3,CAMK2G,C2CD2,ARHGEF10,RIMS2,HDAC4,ARMCX2,RASGRP1,EGR3,FGFR1,GNG4,GRIK5,MYO7A,NF1,NPR2,PCDH9,PFKFB3,RELN,PTPRE,ENOX1,ZMAT4,TRIM68,TCP11L1,EMID1,PREX2,SNCA,ST5,SYN2,MCF2L,DICER1,TIAM1,FAM155A" Drug 6644_DN Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-04 1.00E+00 4.17E-03 4.70E-02 38 191 "ADCY6,APBB2,MARK4,SYNJ2,CCNT1,WHRN,HINFP,VCAN,PDE4DIP,CNTNAP2,FAM169A,DAPK3,GIT2,KIAA0753,FAM13A,EIF4G1,ETV1,ZNF589,SPIN1,STON1,HLF,LSS,MAP4,MAPT,MMP16,MX1,NEK1,NF1,PIK3R1,PLCD1,PEX26,KDM4B,SPTAN1,KAT6B,TRIO,ZBTB38,KAT6A,AAAS" Drug 6718_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-04 1.00E+00 4.17E-03 4.70E-02 38 191 "AP2A2,CDC42BPA,MADD,CDK13,SLC4A4,STX16,CBFA2T2,HOMER3,CREM,VCAN,CNTNAP2,TBC1D5,KIAA0753,EDIL3,FCF1,IRAK4,TUBD1,ETV1,TRMO,OGA,DENND2A,USP19,GPD2,MAP4K5,BACH2,INPP5B,KPNA5,CLDN11,GRAMD1C,PTK2,ZSCAN2,TMEM231,CLIP1,SLC14A1,SS18,TCF4,ZEB1,PHTF2" Drug 4563_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.00E-04 1.00E+00 4.17E-03 4.70E-02 38 191 "ADCY6,NME5,C1QTNF1,BIN1,MARK4,CFLAR,SCAPER,AP4M1,CHN2,PLEKHB1,STOML1,QKI,FAM131B,TBC1D5,PARD6A,FCF1,CSPG5,STON1,GUCY1A1,HAS2,HNMT,MITF,NDP,PDE1C,PTPRN2,CSRNP3,ZNF667,CDK19,CEP68,ARHGEF9,FAM208A,TMPO,SMUG1,UBTF,WIPF1,ZNF32,TRIM9,HPS4" Drug CID000009641 "2,2,3,3,4,4,5,5-octafluoro-1-pentanol" Stitch 4.01E-04 1.00E+00 4.19E-03 4.72E-02 7 14 "CFLAR,SUMF2,STX2,GPR162,FUZ,STX1A,ST8SIA2" Drug CID000009609 ethyl sulfide Stitch 4.01E-04 1.00E+00 4.19E-03 4.72E-02 7 14 "ALDH7A1,DBT,MAT2A,MID1,PBRM1,CLSTN2,ZEB1" Drug CID000196705 alpha-CaM Stitch 4.03E-04 1.00E+00 4.20E-03 4.73E-02 17 62 "ALCAM,MYH7B,CALM1,CAMK2B,KRIT1,CDH2,STX2,CAMKK2,MAP2,MAPT,RELN,RDX,DDN,STX1A,SYN2,ZIC1,ZIC2" Drug 2679_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.05E-04 1.00E+00 4.21E-03 4.74E-02 36 178 "CLK4,C3orf14,MTUS1,SYT13,AMPD3,ATP6V0A1,TAOK2,TPP1,ABCG2,CREM,USP6NL,ZNF337,DGKG,DBT,FAM13A,MBNL2,ENO2,AGAP2,PDLIM5,ATP2C1,OGA,GALC,STON1,MUM1,PDE4B,PMP22,LRP12,MBOAT7,PRKACB,MARCH1,ZNF821,HSPA4L,SPTB,TPM1,ZBTB38,FXR1" Drug 6047_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.05E-04 1.00E+00 4.21E-03 4.74E-02 36 178 "ALCAM,CFLAR,KRIT1,TAOK2,CLCN3,HOMER3,ARMC8,PDE4DIP,ZBTB24,RHOBTB1,ANKRD46,EIF5,EZH1,ARMCX1,TBC1D16,JAK2,SETD4,PDCD2,PIK3R1,MAP6D1,TRAPPC13,ZFP30,SYBU,ZKSCAN3,ZNF302,CEP68,KANK1,ZC3H4,ARHGEF9,ASTN2,FAM208A,CHST8,ZIC1,ZNF23,MAP3K12,HPS4" Drug 4716_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.05E-04 1.00E+00 4.21E-03 4.74E-02 36 178 "NME5,ATP1A3,FUBP1,QKI,SOCS5,ZNF337,MAML1,SPOCK2,HIPK3,FCF1,RASGRP2,IP6K2,ATP2C1,SESN1,GLYR1,GRIK5,KCNH2,KITLG,NFYA,CNOT4,SMIM7,STRN3,PPP5C,PRKAB2,FBXW7,CPEB3,PPP4R3A,SNCA,ZBTB43,DDN,SAMSN1,PLCB1,ZMAT3,TRPM2,ZNF24,RNF146" Drug 3998_DN Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.05E-04 1.00E+00 4.21E-03 4.74E-02 36 178 "CDC42BPA,PKP4,CDC14B,SPAG9,SLIT2,TBC1D5,NR1D2,EGFR,EIF4G1,POLR1B,SPIN1,FERMT2,PCLO,AGFG1,IL6ST,MAP4,MBP,MYO6,NEK1,TMEM260,RBBP6,SLC25A36,KIRREL1,SEC14L1,CCDC88A,SMARCC2,MYCBP2,TROVE2,PRRC2C,TBL1X,TCF4,DICER1,KAT6B,USP1,ZBTB38,FXR1" Drug CID000176265 gacyclidine Stitch 4.09E-04 1.00E+00 4.21E-03 4.74E-02 12 36 "ACHE,BCHE,ENO2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,LAMP2,RTN4" Drug 3739_UP Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "RALGAPA1,ASPHD1,LTBP4,APAF1,DNAH17,KSR1,CA12,TAOK2,RAB33A,FAM149A,AKAP5,CREM,CSF1R,ERC2,HS3ST2,DTNA,NCALD,AGAP2,FYB1,GNAL,SOX21,TJAP1,ITGA7,KCNN1,LIG4,OPRL1,PALM,RASGRF1,PNMA8A,CPEB3,DDN,ARC,ZEB1,SYNE1,DOCK9,R3HDM1,CHST5,OSBP2,XRCC4" Drug 5694_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BBOX1,APBA2,GAS7,SGCE,CAST,CBFA2T2,CRYBB1,IPCEF1,DTNB,NSG1,SRCAP,RUNDC3A,CACFD1,GRM8,ADAMTS6,ICA1,IFI16,KCNJ5,KPNA5,MATN3,NOVA2,RETREG1,PLCD1,LRP12,PPARA,PTPRO,MYH15,LMO3,PHLDB1,PLCB1,TAL1,TCF4,DOCK9,HIF3A,TMEM121,CHST5,UBE3A,SLC30A3,HRASLS" Drug 3537_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AK2,BEGAIN,BIN1,RASL11B,CFAP410,CA12,QKI,TOM1,ACSL4,ZNF589,BAIAP2,FHL1,FLNC,PRELID3A,MSL3,HNMT,ADAM22,NEK1,NF1,PALM,PLXNB1,POLG,PRKAR1B,PRODH,ZDHHC14,EMID1,SEMA6D,SH3BP2,KIF13A,RBM34,CEP68,PHLDB1,MCF2L,CHST8,SLC44A1,PARD3,SPHK2,MAP3K12,UBE3B" Drug 3663_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,ADD2,LDLRAD4,CFAP410,CAMK2B,KCNAB3,AKAP5,IPCEF1,SPOCK3,DTNB,SNX29,RGS17,PIPOX,DLC1,HPCAL4,PDLIM5,NSG1,LILRA2,PADI2,ITPKA,KCNN1,LAMA2,MARK1,AFDN,ADAM22,NELL2,NPTX1,CDK18,FXYD1,NECAB2,PTPRD,RORB,SALL1,SH3BP2,PPM1E,NFASC,SYNE1,TUBB1,SLC17A7" Drug 6304_UP Nitrendipine [39562-70-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AMH,ANK2,SHROOM2,KIF1A,ARHGEF2,TAOK2,RAB28,STOML1,AKAP6,AATK,SUSD5,PHF14,ARMCX2,STX2,ABCA8,FYB1,KCNMB4,CACFD1,IL6ST,KCNN1,MX1,NNAT,NPY,MAPK10,SAMD9,CNTLN,SUGCT,FAIM2,KDM4B,TROVE2,PHLDB1,ZEB1,TPM1,UGT8,LMF1,NT5M,EVI5,PHTF2,AAAS" Drug 3801_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADGRB2,BMPR1B,BAIAP3,USP2,CD86,CDO1,TAOK2,RAB33A,HAPLN1,CSF1R,EDNRA,MBNL2,EPB41,PDLIM5,SIGLEC8,GATM,GFER,GLI2,GNAL,LILRA2,TPPP,ICA1,MYT1,NCAM2,NF1,NPTX2,PPARA,GDPD2,SUSD4,SLC2A5,PKNOX2,SLC11A1,SLC12A4,SOX15,RBM26,LMO3,TAL1,UCHL1,SLC17A7" Drug 6163_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASPHD1,BCAS1,CDK10,SLC4A4,AZGP1,NDST3,AKAP6,DAPK3,SPOCK2,HEYL,MRNIP,VPS13B,RASGRP2,ETV1,FGFR1,KHDRBS3,GSTM5,AP4S1,HNMT,KCNJ5,SAMD14,RETREG1,CNNM2,PTCH1,MARCH1,CEP97,SH3BGR,SH3BP2,PPM1E,ZHX3,ZSWIM8,IQSEC2,SEPT8,TRPS1,UBE3A,VSNL1,KCNK12,PRDM10,KCNAB1" Drug 5885_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "CASK,SLC4A4,EIF4G3,ARHGEF7,CNOT8,CSF1,APPL1,DCAF8,IRAK4,ING4,STX2,ETV1,ANKMY1,CGREF1,FYN,GAD1,HNMT,SHISAL1,KIF2A,MEIS1,TAGLN3,NFYA,PIK3R1,PID1,ROGDI,REV3L,RXRA,SUPT20H,AMBRA1,FNDC3A,WDR37,STX1A,SUPT5H,EXOC7,IQCE,AMACR,HIRA,ZNF32,MAP3K12" Drug 2644_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADRA1D,BIN1,APC,FAM131A,MARK4,SYNJ1,SGCE,CACNA1G,CHRNA4,COL9A3,ARHGEF10,SPOCK2,TMCC2,TNK2,RASGRP2,SPEG,ALDH1L1,TDRKH,INPP5B,JAK2,KCNQ3,MEF2C,NPTX1,RETREG1,PTPRH,FAM184A,BEND5,FRMPD1,SLC11A1,LIMCH1,KDM4C,IQSEC2,SS18,SYT5,HIRA,FAM155A,ZFP37,GDPD5,SENP7" Drug 5064_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "APBB2,EPB41L5,BACH1,SYNJ1,STOML1,ARMC8,SLC4A8,CSNK1E,RUSC2,EDNRA,HIPK3,ING4,CDKL3,ETV1,B4GALNT1,TMEM8B,SESN1,USP19,TDRKH,GUCY1B1,BACH2,SHISAL1,KIF2A,MEF2C,SCAMP5,NF1,OGG1,ZSCAN2,AMBRA1,DZIP1,PDZD2,ASTN2,SYNE1,CRTC1,TK2,TPM2,ZNF32,MAP3K12,DPF3" Drug 5295_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ALCAM,LTBP4,LRRFIP1,LHX2,VAX2,HOMER3,AKAP7,GPRASP1,KIAA0586,GIT2,DPH1,DTNA,FCF1,MRNIP,COQ7,DLC1,KHDRBS3,SRCAP,NFYA,POLG,PPP5C,PRODH,TMEM231,SBF1,SH3BGR,COA1,THSD1,TTBK2,EXOC7,IQCE,TRIM2,SLC44A1,TPM1,ZNF74,EMSY,HPS4,SEMA3B,ITM2C,MPPE1" Drug 3396_DN Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,NME5,LTBP4,BIN1,APLP1,CDK13,DNAH17,MARK4,SCAPER,CFAP410,SLC16A4,CLGN,CACNA2D2,ARHGEF6,WHRN,PDE4DIP,CELSR3,PLXNC1,ZNF589,IQCG,TMEM8B,RUNDC3A,ELOVL5,ZNF862,P2RY1,PCDH9,CDK18,PLCD1,PTN,ZFHX4,PEX26,SLC9A5,DOK5,THSD1,SMG6,DOCK9,FAM155A,REEP1,DNALI1" Drug 5108_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,MARK4,ALDH7A1,CACNA1A,LARGE1,CHN2,WHRN,RCHY1,BRINP1,SPOCK3,CDON,EDIL3,EDNRA,MBNL2,BAIAP2,IL12A,MATN3,TAGLN3,NEK1,NF1,PDE4A,BCAS3,PID1,RGS4,CSRNP3,SNCA,RBM34,TROVE2,NXT2,SYN2,SYT1,KIAA1107,TNS1,METTL3,ZNF24,ZNF225,EVI5,SEMA3B,SENP7" Drug 1537_DN Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SLC4A4,CAMK2G,KRIT1,SLIT2,SULT4A1,AKAP7,SH2B1,CSNK1E,ARHGEF4,DAPK3,OPTN,ING4,VPS26C,SCML2,FGFR1,OGA,ZNF276,GLYR1,CACFD1,PRKAR1B,PTCH1,GTDC1,NEK11,TCP11L1,SUPT20H,AMBRA1,ELMO2,FNBP1,POGZ,ST5,ARC,BHLHB9,METTL3,PLPPR2,VIPR2,REEP1,TFIP11,MARCH8,PHTF2" Drug 5765_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NME5,ADGRF5,KIF1A,ADGRB1,CACNA1I,CA8,SYNGR3,LY86,CNR1,CSF1,ARMCX2,ECM2,EDIL3,EDNRA,CNNM1,TNK2,RCAN2,NCALD,ETV1,EZH1,F5,DLC1,OLFM1,HPCAL4,AFF2,DCTN2,FYB1,POLL,KCNB1,KCNN1,LSS,C1orf54,DZIP1,SPTAN1,ZFPM2,THRA,BHLHB9,WIPF1,SLC17A7" Drug 6738_DN Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASIC1,AMPD3,LGR5,MARK4,MYRF,LDLRAD4,CBFA2T2,WHRN,SLC4A8,VCAN,PARD6A,MBNL2,FYN,B4GALNT1,COPS8,POLL,SYNPO,MIA2,ZNF862,MYT1,PLXNB1,MAPK7,APTX,ZCWPW1,DCUN1D2,KIRREL1,TRAPPC13,DZIP1,MYH15,ARHGAP26,DDN,LHPP,PHLDB1,EXOC7,DOCK9,TRIO,VIPR2,ZNF24,TFIP11" Drug 1507_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,KCNAB2,APC,ATP6V0A1,SCAPER,RAB33A,CNTFR,CSF1R,GREB1,ELMO1,MFAP3L,FAM13A,MBNL2,EIF4G2,C3orf18,PTK2B,FGFR1,AFF2,MSL3,STON1,GRB10,IRF8,INPP1,LMO2,NPR2,CDK18,PPARA,MAPK10,PRODH,KCTD17,ARHGAP26,ZBTB43,PHLDB1,SYT5,TRIM2,PDIA2,SLC17A7,MPPE1,RNF170" Drug 5015_UP Benzbromarone [3562-84-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SLC4A4,ADAM23,CFLAR,SCAPER,GYG2,ASIC3,CRY2,CSF1,RUSC2,EDNRA,CDKL3,SCARA3,OGA,GAD1,ALDH1L1,POLL,SPACA9,BTN2A1,IRF8,ITPKB,KCNN1,KCNQ3,NF1,NTRK3,P2RY1,MTRF1L,LRRN3,MAPK7,ELOVL2,RAD51D,NEK11,CXXC4,MAPKBP1,HECW1,DOCK9,LMF1,NT5M,SEMA3B,TIGD6" Drug 1402_UP Ampyrone [83-07-8]; Up 200; 19.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AMPD3,PRX,PDE8B,ADGRB2,CA12,CACNA1A,CALB2,CNTFR,SH2B1,TMCC2,DPH1,SRPK3,ELN,EFCAB2,CACFD1,KCNF1,LAMA2,GIT1,SAMD14,NTRK2,PFKFB2,DUSP26,PPARA,PPP5C,PTN,PTPRN,PTX3,RNASE1,PLPPR3,RXRA,LIMS2,SLC6A11,ZKSCAN3,SNAP25,ZHX3,SPTB,PLCB1,VGF,VIPR2" Drug 6275_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA1,SYT13,AMPD3,APC,GAS7,ARRB1,RGS20,MARK4,AZGP1,CFLAR,SYNJ2,MTMR2,TAOK2,QKI,CSF1,SIPA1L1,EDN1,EDNRB,SUGP2,ZNF589,COPS8,PCLO,JAK2,PACRG,MAP4,MMP16,MPP2,NF1,P2RY1,RETREG1,ZCWPW1,ZHX3,SPTAN1,TNS2,TRPM2,FAM155A,XRCC4,SLC30A3,SLC17A7" Drug 5611_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADGRB1,USP2,CDO1,CHRNA4,TAOK2,CNR1,AKAP5,CSF1,SNPH,DGKG,SPOCK2,DMPK,FUT9,SIGLEC8,POLL,SOX21,IRAK3,KCNJ5,LMO2,AFDN,MYO7A,NPY,NTRK3,C19orf57,WDR25,CNTLN,ENOX1,ZMAT4,KLHL11,FRMPD1,KANSL3,MAPKBP1,KIF13A,CDK19,SYT5,PIK3R5,FLRT2,XRCC4,SPHK2" Drug 948_DN Y-27632; Down 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "OGT,PKP4,ARRB1,ATP6V0A1,PLEKHB1,CLCN3,QKI,ARHGEF6,PARD6A,MRNIP,RRAGB,F8,KAT8,PDLIM5,INPP5K,GLYR1,RBPJ,INPP5B,KCNF1,KHK,MAP4,MAPT,MPP2,NCAM2,CNOT4,SMOX,RETREG2,RAD51D,CHD9,FBXO11,NUBPL,ZKSCAN3,ERC1,CEP68,ANKRD12,AP4E1,NR2C2,KLC2,ZNF142" Drug 6040_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASIC1,KIF1A,CACNA1I,LDLRAD4,KYAT1,USP2,ARHGEF2,SEPT7,CRLF1,CACNA2D2,SRSF11,FOXN3,PLEKHB1,GREB1,DAPK3,DNM1,SEZ6L2,PLXNC1,RRAGB,EZH1,FER,FGFR1,SRCAP,TDRKH,CNTRL,ELOVL5,DHX35,LMO2,KITLG,SLC25A23,ZDHHC14,TCP11L1,SH3BP2,BTBD7,PHLDB1,STX1A,PCDHA5,DICER1,ZNF34" Drug 2340_UP Ofloxacin [82419-36-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,ADD2,APAF1,APOC1,CHGB,TAOK2,CNTN1,CSF1,ZFYVE16,DAPK3,RCAN1,E2F5,EDNRB,CNNM1,EIF4G2,KAT8,ATP2C1,MSL3,INPP1,MAP4,MYT1,NF1,P2RY1,PCDHGC3,LRP12,RGS12,FERMT1,CCDC88A,KDM4B,ZC3H13,SPTAN1,CAMTA2,RPGRIP1L,CRTC1,TNS1,HIRA,EMSY,PCBP4,UBE3B" Drug 2241_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADD2,AP2A2,LTBP4,AMH,BIN1,APOC1,ALDH7A1,TPP1,HOMER3,DCAF4,DOCK4,RASSF2,RUSC2,MBNL2,EGR3,NRN1,DLC1,FGFR1,FHL1,FLNC,GNAL,PRUNE2,C2orf72,KCNH2,ADAM22,ZNF862,MYT1,NEFM,NF1,P2RY1,PLCD1,LRRN3,MAPK7,VPS13C,ST6GAL1,SLA,SLC2A5,WSCD1,SLC30A3" Drug 5503_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,BIN1,RASL11B,ATP1A3,SLC4A4,ALDH7A1,SGCE,CACNA1I,B4GALT6,CNTNAP2,DZIP3,RIMS2,ING4,EPB41L2,ZNF589,FHL1,CNTRL,GRB10,KCNH2,KIF5A,MMP16,NFYA,C1orf54,NEK11,RPS6KA2,PEX26,KANSL3,COA1,SMARCA4,TMCC1,ATP10B,TROVE2,ST5,PLCB1,ASTN2,ANKRD12,CRTC1,XRCC4,EVI5" Drug 5915_DN rotenone; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA2A,SEMA6A,TRMT9B,APBB2,SLC4A4,CA12,HAP1,CD86,PLEKHB1,LHX2,NCOR2,CSF1,FAM169A,GPRASP1,TNK2,ANKMY1,KAT8,B4GALNT1,SRCAP,GLYR1,IL6R,KHK,MID1,MMP17,NFYA,NPR2,PALM,RETREG1,RETREG2,ZSCAN2,SLC2A5,ARHGEF40,RBM34,THSD1,STX1A,ARC,TNS1,SLC30A3,ITM2C" Drug 3211_UP "Zidovudine, AZT [30516-87-1]; Up 200; 15uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADD2,ADGRF5,APAF1,CDK13,SLC4A4,CBFA2T2,TPP1,BAG4,OSBPL3,VCAN,RIPOR2,MFAP3L,FRY,ERCC2,REEP2,FGFR1,SCARA3,PRELID3A,DLL3,SIGLEC8,SRCAP,GRIK5,IRF8,KCNN1,KCNN2,KIT,ADAM22,NOVA2,PCBP3,PPP5C,CNNM2,TCP11L1,SGK1,SLC11A1,MTCL1,TNS1,FLRT2,CLIP2,ZNF711" Drug 1320_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,AP2A2,DOC2A,STX16,SYNJ1,SCAPER,NFS1,CLGN,BAG4,CPS1,OSBPL3,ZFYVE16,DBT,SPATA2,GSDME,HIPK3,PTK2B,SEPT9,GLYR1,NCKAP1L,MAP4,N6AMT1,RETREG1,MINDY2,MAPK3,C1orf109,TMEM231,RASA3,FUZ,MYH15,ZBTB43,PBLD,EXOC7,SLC44A1,KAT6B,SMUG1,TFIP11,KCNAB1,MARCH8" Drug 6651_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,SPARCL1,ANK2,RASL11B,AZGP1,RGS11,CAPN3,CRLF1,EPS15L1,VAX2,SLC4A8,NCOR2,CNTNAP2,RIMS2,MFAP3L,DMPK,DUSP9,EDNRB,TNK2,ELN,OLFM1,PRELID3A,CACFD1,ATXN2L,ITGA7,MMP16,NEFM,NOVA2,NTRK2,PDE4B,PTPRD,RGS12,PNMA8A,FRMPD1,PHLDB1,TPM1,TRIO,SLC17A7,DPF3" Drug 7520_UP Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BEGAIN,CDC14B,CFAP410,PLEKHB1,HAPLN1,CSF1,CSNK1E,PDE4DIP,MAML1,DAPK3,C2CD2L,KLHL3,DTNA,VPS13B,KAT8,BAIAP2,SCARA3,PDLIM5,CGREF1,GAD1,TMEM8B,BTN2A1,ATXN2L,SCIN,MIA2,MMP17,ZNF862,CDK18,PRPH,APTX,CCDC40,MAPK12,STUM,ASAP3,FBXW11,TRIM2,TRIO,NT5M,PCBP4" Drug 7357_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "DOC2A,LGR5,SLC4A4,SLC2A11,LDLRAD4,CAMK2B,USP2,SLC16A4,ARHGEF2,HOMER3,COL9A3,FAM169A,SPOCK3,DTNA,EDNRB,ING4,SRPK3,ZNF44,TDRKH,GRM8,ATXN2L,ELOVL5,MAP4,ADAM22,MSR1,NF1,SETD4,SLC25A23,RIPOR1,RGS12,FBXW7,SBF1,ZNF821,SH3BP2,CNKSR2,RGL1,PHLDB1,DICER1,FAM13C" Drug 2929_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,APBB2,APOC1,ARHGDIG,CACNA1I,CA12,CACNB4,ASIC3,SPOCK2,EGFR,DLC1,BAIAP2,DCTN2,FERMT2,ITPKA,MAP4,NINJ2,NNAT,NPR2,NPTX2,CLDN11,PPARA,ELOVL2,KCTD17,RASA3,CCDC92,EPN2,MAPKBP1,ZHX3,ZC3H13,SYN2,ADGRL3,TBCEL,PCDHA3,VIPR2,KCNK12,SLC17A7,PCBP4,TIGD6" Drug 2774_DN Racecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "MTUS1,APBB2,ARNTL,RIPK1,CBFA2T2,VAX2,COL4A5,PREPL,TBC1D5,MFAP3L,TSPAN5,HIPK3,CNNM1,SCML2,ZNF589,STON1,CNTRL,BTN2A1,KCNH2,MMP16,MPP2,ADAM22,ZNF862,NEK1,RETREG1,PLCD1,WDR25,SH3BP2,SLC6A8,SLC22A4,SOX3,KDM4C,CDK19,THSD1,SIK3,UBE2H,VLDLR,LMF1,PHTF2" Drug 1677_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASPHD1,LTBP4,PPFIA3,CDC14B,MADD,ARNTL,ARRB1,NCOA1,RIPK1,CFLAR,CCNT1,SCARB1,CNOT8,GIT2,MFSD10,FECH,CAMKK2,GAA,IPO5,NPR2,OGG1,TMEM104,NEK11,ATXN2,PEX26,SMARCC2,CDK5RAP2,ARHGEF9,TACC1,EXOC7,PDLIM2,BEX4,CABIN1,HIRA,UBTF,KLC2,HPS4,SEMA3B,MPPE1" Drug 2345_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "PKP4,CFLAR,SYNJ2,HIP1R,USP2,VAX2,PICK1,CNTN1,SH2B1,AATK,ZNF337,DAPK1,DAPK3,KIAA0753,SPOCK3,DTNA,GFER,POLL,KCNMB4,LILRA2,GRIK5,INPP5B,MAP4,NF1,NINJ2,CNOT4,NLE1,SLC25A23,PLPPR3,SH3BP2,SMARCC2,KDM4C,CLSTN2,ZC4H2,SZT2,KAT6B,PIK3R5,EMSY,KCNAB1" Drug 2255_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADD2,AK2,ALCAM,BBOX1,APC,N4BP2L1,ADGRB3,CFLAR,KSR1,GYG2,BAIAP3,CFAP410,TAOK2,VCAN,MYEF2,DMPK,SHANK1,HIPK3,TENM1,EPHB1,SCARA3,CSDC2,HPGDS,GRM8,TJAP1,MYO7A,CNOT4,MTRF1L,PURG,MINDY2,LRRN3,SCN2B,FRMPD1,ASAP3,SLA,SZT2,TK2,RIMBP2,SLC17A7" Drug 3711_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA1,LTBP4,GAS7,BMP7,RUNX1T1,CD86,SULT4A1,LRIG1,SPOCK2,BRINP1,EGFR,TNK2,HPCAL4,AFF2,DCTN2,ZNF44,IQGAP2,SIGLEC8,GRIK5,GRM2,SHISAL1,TJAP1,KCNN1,KIFC3,LSS,ADAM22,LYRM9,NNAT,MASP1,KCNIP1,SEMA6D,PKNOX2,FAIM2,NFASC,FAM189A1,PDIA2,FLRT2,REEP1,SLC30A4" Drug 4816_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SEMA6A,TRMT9B,CDC14B,N4BP2L1,CFLAR,LDLRAD4,AKAP6,RIMS2,TMCC2,MBNL2,TNK2,F5,FHL1,FYB1,TMEM8B,SRCAP,GNAL,TDRKH,GRM8,ATXN2L,MEF2C,ADAM22,NNAT,NPTX1,PALM,MAPK7,DCHS2,C1orf54,EMID1,ST6GAL1,CNKSR2,IZUMO4,HECW1,JMJD6,ARC,OSBP2,WIPF1,XRCC4,SLC30A3" Drug 2392_DN Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,ALK,CDC42BPA,MARCH3,NCOA1,SYNJ2,CFAP410,CAPN3,CAST,KRIT1,IQCK,SH2B1,TBC1D5,MAML1,SGSM2,TSPAN5,FCGRT,ZNF589,FHL1,SRCAP,MAP4K5,ELOVL5,LIG4,MAP4,RETREG1,FAM184A,ZNF493,FBXW7,ZNF671,MAP6D1,NUBPL,PJA1,EXOC7,TBL1X,HIF3A,ZMAT3,TLR4,KAT6B,PIK3R5" Drug 4698_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASIC1,NDRG2,ADORA1,SEMA4G,PDE8B,ADAM15,AZGP1,CFLAR,QKI,TBC1D5,MAML1,EDNRA,RASGRP2,NCALD,PTK2B,IQCG,FLNC,DCTN2,GALC,SRCAP,MALT1,GLYR1,TDRKH,GSTM5,IL6ST,INPP1,LIG4,MMP16,PLCD1,LRP12,PPP2R2B,MAPK7,CNNM2,SNRK,RGS12,ASAP3,DMXL2,PCDHA6,SEMA3B" Drug 6426_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,CDC42BPA,APBB2,PPFIA3,MARCH3,ARHGEF7,CA12,CAMK2B,ARHGEF2,TPP1,CSF1,CSNK1E,VCAN,GPRASP1,MFAP3L,EDIL3,IRAK4,STX2,ETV1,FHL1,FYB1,FYN,SPACA9,ATXN2L,ELOVL5,MAPT,MBD1,MMP16,SLC11A2,POLG,WDR25,ST6GAL1,LHPP,CAMTA2,HIRA,UBE2H,MPPE1,ST7,KAT6A" Drug 7456_DN Chlorzoxazone [95-25-0]; Down 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AK2,NCOA1,ATP6V0A1,MPDZ,SYNJ2,RAB28,HINFP,PPP6R2,DBT,SGSM2,DNM1,MED12,DTNA,PRKAG2,SEPT9,SLC2A6,GIT1,SMIM7,FA2H,CYBC1,C1orf109,GTDC1,ROBO1,AMBRA1,PEX26,EPN2,ZSWIM8,SPART,ITPRID2,NXT2,ARHGEF9,VPS13A,TACC1,TBL1X,TRIM2,LMF1,ZBTB14,REEP1,GDPD5" Drug 2749_DN Monocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "CDK10,NCOA1,CFLAR,BMP7,MTMR2,CA4,SRSF11,FOXN3,CLCN3,FAM189A2,QKI,HOMER3,CREM,KIAA0586,MFAP3L,C2CD2L,NCALD,ACSL4,ZNF589,SEMA4D,SRCAP,AHDC1,CACFD1,KHK,MITF,NFYA,SLC11A2,SETD4,SLC25A23,MAPK7,SBF1,PLCB1,ZNF34,TSN,VGF,TFIP11,MAP3K12,GDPD5,HPS4" Drug 842_UP "N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,EPB41L5,PPFIA3,ARHGDIG,PDE8B,ADGRB2,CFLAR,ST3GAL5,BAIAP3,BAG4,CTH,BRINP1,DBT,MFAP3L,SLC12A6,SUGP2,SRCAP,CNTRL,SPACA9,RNFT2,TJAP1,INPP5B,LIG4,LYRM9,NF1,OXTR,PRPH,SAFB,BTBD7,ZBTB43,THSD1,CEP68,DIP2A,PLCB1,TACC1,SZT2,ZKSCAN5,UBTF,SH3GLB2" Drug 2249_UP Ampyrone [83-07-8]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,CDC42BPA,APAF1,KCNAB2,MARK4,ADGRB3,BTK,SGCE,BAIAP3,HOMER3,CNTN1,SPOCK3,SNX29,FHL1,AGAP2,PRELID3A,GAD1,PRDM5,GRM8,IL6ST,ITGAM,MAP4,MYT1,NF1,LRP12,RETREG2,MAPK7,PTPRO,ZMAT4,TRIM68,SH3BP2,ST6GAL1,SLC11A1,MYH15,TSNAXIP1,HECW1,KIAA1107,EVI5,SLC17A7" Drug 4183_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ACHE,SPARCL1,DOC2A,BIN1,PPP4R4,ZSCAN18,FUBP1,CACNA2D1,LDB2,LARGE1,EPS15L1,VAX2,HOMER3,AKAP5,CYBB,SPEG,CORO2B,PDLIM5,RUNDC3A,GSTM5,AP4S1,ICA1,MMP16,MSR1,MX1,LYRM9,NTRK2,MTRF1L,ZSCAN32,GAL3ST4,RGS12,PNMA8A,RPS6KA2,IZUMO4,CDK19,TBCEL,TNS1,CHST5,KCNAB1" Drug 3519_UP Etomidate [33125-97-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NME5,ALK,SEMA7A,APBA2,DDO,ATP2A2,ADGRB1,ARHGEF2,FOXN3,TAOK2,CNN3,CABP1,COL9A3,CPS1,NCOR2,PHF14,DOCK4,RASSF2,TMCC2,C3orf18,ETV1,ANKMY1,FAM198B,ERAP1,GRM8,ICA1,GPR85,PPP5C,SAMD9,ZFP2,FRMPD1,SMARCD3,ATP10B,SYT5,TBCEL,PCDHGA10,TNS2,CRTC1,KCNAB1" Drug 5434_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "KIAA1324,APBA2,APLP1,PPP4R4,ALDH7A1,ST3GAL5,CAMK2G,TAOK2,C2CD2L,DMPK,EDNRA,CELSR3,EGFR,RASGRP2,SCARA3,AGAP2,TMEM8B,ALDH1L1,KCNN1,MAN2A2,MAP2,MAP4,MATN3,MMP16,GIT1,PLTP,RIPOR1,RPS6KA2,RYR3,ZNF821,RASA3,FAM214B,PDZD2,ZHX3,IQSEC2,JMJD6,TK2,MAP3K12,PLSCR4" Drug 6099_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "RALGAPA1,ASIC1,BIN1,ANK2,CDH2,LY86,CNR1,HAPLN1,VCAN,CYBB,RASSF2,BRINP1,DBT,JAKMIP2,TENM1,SRPK3,PTK2B,PRUNE2,PCLO,GRIK5,GSTM5,KIT,NF1,NTRK2,NTRK3,SERPINI1,PILRA,PPP5C,CNTLN,PTX3,RPS6KA2,ARHGEF40,SLC11A1,CXXC4,SPTAN1,PHLDB1,TRIM2,TEK,GPR161" Drug 4258_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "PPFIA4,DDO,ARSE,PTCH2,SLC16A4,ARHGAP33,DLGAP1,NRXN3,AKAP7,COL9A3,NRG2,RIMS2,CYBB,BRINP1,SV2B,HS3ST2,TNK2,EFCAB2,SIGLEC8,ADAMTS6,PACRG,MGAT3,NF1,NNAT,NRCAM,NTRK2,NTRK3,P2RX7,POU6F1,PTPRN2,RNASEL,RTN1,SCN2B,NFASC,SYT5,SYNE1,PHF24,WIPF1,NLRP3" Drug 5682_UP Niridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,NDRG2,ALK,SEMA4G,SLC4A4,SGCE,CDH2,CHRNA4,STOML1,WHRN,VCAN,RASSF2,SPOCK2,DBN1,HS3ST2,ECM2,DUSP9,TNK2,ZNF589,GAD1,SIGLEC8,DISC1,ADAM28,LYVE1,GLI2,LILRB4,TDRKH,LPAR4,PCLO,KCNN2,NF1,ENPP2,KCTD17,MAPKBP1,DOCK9,DICER1,CLIP2,ZNF711,EMSY" Drug 1861_UP Triamterene [396-01-0]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AMT,KCNAB2,APBB2,APC,FAM131A,ARNTL,ARRB1,N4BP2L1,KIF1A,SYNJ1,ZMYM4,CHN2,FHL5,CSF1,CSNK1E,SEC14L5,ELN,INPP5K,TXNL4A,FERMT2,GUCY1A1,ELOVL5,SMAD1,MBP,GIT1,NTRK2,PIK3R1,PPP5C,PTN,ZNF667,ARHGAP26,TSPYL2,CUX2,CHST8,PARD3,KAT6B,PLPPR2,LAT2,PARP11" Drug 6096_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,ALCAM,AMT,APBB2,ARHGDIG,CFLAR,SYNJ2,GYG2,CACNA1I,CA12,CAMK2G,MAGI1,FOXN3,FAM189A2,CRMP1,PDE4DIP,RIMS2,MAML1,GIT2,RCAN1,DTNA,DUSP9,C3orf18,DLC1,FHL1,SRCAP,IPO5,MMP16,NEK1,NPTX1,NTRK2,NECAB2,RGS3,ZNF821,SNCA,TBCEL,TPM1,ZKSCAN5,TIGD6" Drug 1326_DN "Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BRAP,APAF1,APBB2,BCL7A,ARHGEF7,ENTPD6,AP4M1,CLTB,IQCK,RNF14,OSBPL3,TM9SF4,DBN1,SPATA2,GSDME,PCOLCE2,ANKFY1,PDLIM5,AHDC1,LILRA2,TJAP1,LIG4,MATK,NF1,NFYA,SETD4,RAD51D,RET,GSTCD,NUBPL,ARHGEF40,PDLIM2,TCF4,PARD3,LAT2,XRCC4,ZNF142,FTSJ1,ACTR3B" Drug 2398_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG3,AP2A2,CDC42BPA,APAF1,APBB2,PDE8B,SLC4A4,CALB2,RUNX1T1,USP2,CBFA2T2,ARHGAP33,CHGB,CHN1,SNPH,SPOCK3,EIF1,PDLIM5,PRELID3A,ERAP1,AP4S1,IL6R,KCNJ5,NF1,PLCL1,PPP2R2B,PTCH1,FBXW7,KCNIP1,FERMT1,CXXC4,SS18,PDLIM2,CRTC1,ZNF34,TPM1,AMACR,EMSY,ADAMTS9" Drug 3901_DN U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,AP2A2,KCNAB2,APBB2,GAS7,PLA2G4C,CDK13,ALDH7A1,CFLAR,CBFA2T2,PICK1,CRY2,NCOR2,DBN1,FGFR1,FHL1,ATP2C1,B4GALNT1,GCNT2,SRCAP,GRM8,GSN,ATXN2L,ICA1,KCNH2,KITLG,NF1,SLC11A2,ELOVL2,CCDC40,TCP11L1,RASA3,ASAP3,CDK5RAP2,LIMCH1,RGL1,SLC44A1,PARD3,PLPPR2" Drug 2381_DN Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,ALK,ARNTL,MARK4,NCOA1,CFLAR,LDLRAD4,CAMK2G,SLC25A14,CD86,SOCS6,CSF1R,SPATA2,TNK2,F5,FGFR1,FHL1,USP19,RAB40B,LILRA2,LIG4,GIT1,NF1,PIK3R1,SNRK,TMEM231,MAP6D1,PPP4R3A,DOP1A,ZBTB43,POGZ,STXBP1,HIF3A,SLC44A1,TK2,KAT6B,UBTF,WIPF1,MARCH8" Drug 4277_DN Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "PKP4,NFS1,KYAT1,KRIT1,ARHGEF2,SRSF11,SOCS6,CHN2,HOMER3,CPS1,DZIP3,APPL1,ARMCX2,ING4,DENND4A,VPS26C,FCGRT,POLL,GPR37,BACH2,PALM,PDE1C,PFKFB2,STRN3,LRP12,SMARCA4,LIMCH1,KDM4B,PDZD2,SPTAN1,SS18,PLCB1,SYT1,ASTN2,XRCC4,EVI5,HPS4,KCNAB1,UBE3B" Drug 3332_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AK2,CDC42BPA,CDK10,BCL7A,CFLAR,CAMK2G,SOCS6,PLEKHB1,RAB28,QKI,SLC4A8,ZNF337,TOM1,SUGP2,PLEKHA1,TXNL4A,PRRC2B,GRB10,INPP5B,ITPKB,MATK,ZNF862,NFYA,PRKAR1B,CNNM2,WBP1L,CEP97,CLIP1,SH3BP2,FERMT1,PPP4R3A,SPTAN1,POGZ,SLC44A1,BHLHB9,VAV1,XRCC4,ZBTB14,FZD3" Drug 3767_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,C1QTNF3,AMPH,APAF1,STX16,FUBP1,SYNGR3,WHRN,CNTNAP2,DAPK1,MFAP3L,SPOCK3,MRNIP,CDKL3,PDLIM5,NSG1,ALDH1L1,RUNDC3A,RAB30,GNAO1,KCNB1,KCNJ5,KCNN1,KIT,MEF2C,MGAT3,MMP17,MT1M,NRCAM,ACSM5,RGS3,SH3BP2,PPP4R3A,SPTB,SSTR2,MCF2L,PIK3R5,PDIA2,ADAMTS9" Drug 2701_UP "estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "MTUS1,PKP4,ZBTB10,SLC16A4,TAOK2,EPS15L1,RAB33A,CNTN1,CREM,DZIP3,USP6NL,DGKG,DBT,HIPK3,FCF1,SRPK3,EIF1,FHL1,CSPG5,LILRA2,GSN,ITGAM,MEF2C,TAGLN3,MINDY2,PTPN13,RBBP6,RGS4,PNMA8A,HSPA4L,CXXC4,RPGRIP1L,CRTC1,TPM2,SSBP2,HIRA,UBE3A,PRDM10,PHTF2" Drug 3788_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,FAM135A,AMT,APC,AQP6,ARRB1,ATP6V0A1,ADGRB2,GYG2,CACNA1A,CACNA2D1,CDO1,PCYT1B,SH2B1,SPOCK2,CHRDL1,REEP2,TOX3,POLL,PRUNE2,KCNF1,KCNJ5,KCNN2,MGAT3,MMP17,GIT1,SAMD14,P2RY13,NCAM2,NF1,FXYD1,SLC8A1,ZNF667,KIF13A,TUBB1,VAV1,LAT2,SLC17A7,DPF3" Drug 6224_DN Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AMPD2,PKP4,CASK,ARHGEF7,KRIT1,SCARB1,ZMYM4,NCOR1,SOCS5,DCAF8,INTS1,GIT2,PARD6A,NR1D2,SEMA4D,AGBL5,FAM69A,JAK2,MAP4,NFYA,PPP3CC,PPP5C,MAPK3,C1orf109,CHD9,ZKSCAN3,SPATA7,ZSWIM8,UHRF1BP1L,POGZ,SUPT5H,ANKRD28,MTCL1,FBXW11,TIAM1,KAT6B,VAV1,FTSJ1,FIP1L1" Drug 7349_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SRPX,BEGAIN,SEMA4G,ATP6V0A1,CFLAR,GYG2,QKI,DMPK,DTNA,DTNB,MAMLD1,MTSS1L,EZH1,FHL1,ERAP1,SRCAP,MALT1,RUNDC3A,TXNL4A,GPER1,CACFD1,ELOVL5,NF1,PIK3R1,RETREG1,RIPOR1,TRAPPC13,SBF1,SUPT20H,SYBU,SMARCD3,RBM34,KDM4C,SPTAN1,ARHGEF9,ARC,KIAA0930,ZNF34,TK2" Drug 4235_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADD2,ADORA2A,ALK,ATP6V0A1,ST3GAL5,CFAP410,CACNA2D1,RUNX1T1,VAX2,CNTFR,CNTNAP2,CYBB,RIPOR2,SPOCK3,HIPK3,LRRC17,EPHB1,PIPOX,PTK2B,FGF1,FGF12,NEU3,TDRKH,LILRA2,STON1,GUCY1B1,LAMA2,SHC3,NRCAM,NTRK2,PTN,PTPRN2,KCNIP1,SLC2A5,PDZRN3,SPTB,MCF2L,TNS1,DPF3" Drug 1391_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; HL60; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,SYT13,APAF1,APBA2,GAS7,SHROOM2,NUMB,BMP7,EPS15L1,CRY2,HINFP,NCOR1,ARHGAP32,C2CD2L,TMCC2,RUNDC3A,ADAMTS13,CACFD1,PADI2,KCNH2,IPO5,GIT1,NTRK3,PLCB2,SLC25A23,PRPH,PTN,RET,RGS12,EXD2,TCP11L1,ZFP30,HECW1,DBNDD2,STXBP1,OBSL1,TK2,PARD3,URM1" Drug 7291_UP Lymecycline [992-21-2]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ARHGDIG,ADAM23,CACNA1A,HAP1,IQCK,ABCG1,CSF1R,FCF1,AASS,DLC1,DENND2A,SPACA9,HSF2,TJAP1,SCIN,MEF2C,CNOT4,NRCAM,GPR85,FA2H,MAPK10,WDR25,ZCWPW1,ZDHHC14,IFT122,KDM4B,DDN,NFASC,LHPP,TROVE2,THSD1,ASTN2,SYNE1,GPR161,TIAM1,PARD3,OSBP2,XRCC4,ZNF74" Drug 1761_DN Syrosingopine [84-36-6]; Down 200; 6uM; HL60; HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BRAP,ADRB2,PKP4,APAF1,ARNTL,RAB29,PTBP2,KRIT1,LRBA,RCBTB2,CTH,HDAC4,DPYSL2,SUGP2,SMC2,MAP4K5,IRAK3,RBPJ,MEST,NUCB2,RETREG2,MINDY2,PPM1B,CLIP1,NCBP3,ATXN7,ELMO2,SP2,ITPRID2,TTBK2,SUPT5H,PRRC2C,CLASP1,TK2,R3HDM1,TNS1,METTL3,HIRA,PDSS2" Drug 2057_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "TRMT9B,ZSCAN18,SLC4A4,LARGE1,HOMER3,AKAP7,DAPK3,DBT,LYPD1,FCF1,ELN,FGF1,FGFR1,TRMO,CINP,TRAF3IP2,GCNT2,HTATSF1,IL6ST,KHK,LIG4,MAPK7,PRPH,PTCH1,CCDC40,TRA2B,ST6GAL1,CDK19,THSD1,CEP68,IQCE,TRIM2,DOCK9,ZKSCAN5,WIPF1,SH3GLB2,EVI5,KCNAB1,PHTF2" Drug 6684_DN Hydrocortisone base [50-23-7]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "TRMT9B,BIN1,PDE8B,SLC4A4,MYRF,CBFA2T2,ABCG2,PDE4DIP,CNTNAP2,KLHL3,CHRDL1,MFSD10,CDKL3,PDLIM5,TRAF3IP2,TDRKH,IL6ST,TM6SF1,MMP16,RETREG1,PRPH,PTN,PTPRN2,TMEM231,C1orf54,FAM184A,KIRREL1,FBXO11,SLC14A1,UNC5B,SPTAN1,KIAA1107,TK2,TPM2,SSBP2,HIRA,LMF1,KCNAB1,DPF3" Drug 2229_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,AMH,SLC4A4,N4BP2L1,TPP1,STOML1,FAM149A,MYRIP,MTSS1L,EPHB1,NCALD,IGSF6,ST3GAL6,FGF13,FHL1,DCTN2,CAMKK2,PRUNE2,HLF,KIF5A,SMAD1,PCBP3,PDE4B,PPP2R2B,GRAMD1C,CRTAC1,RGS12,KLHDC8A,FRMPD1,ASAP3,SLC14A1,LIMCH1,FAIM2,SPTB,SMG6,PCDHA5,GPR161,TRO,KCNK12" Drug 2176_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "APAF1,APC,KIF1A,ADAM15,MPDZ,SH2B1,CSF1,PPP1R16B,ZNF337,TSPAN5,HIPK3,FEM1B,FAM13A,PLXNC1,ZNF589,FHL1,NBEA,GNG4,GRIK5,LSS,CCSER2,PLCD1,ZSCAN32,ZNF493,MAPK12,SBF1,TMCC1,IZUMO4,SPTAN1,ZBTB43,SS18,JMJD6,EXOC7,SLC44A1,KAT6B,VIPR2,MKRN3,EVI5,GDPD5" Drug 7431_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BRAP,APOC1,PPFIA3,CDK10,ADAM15,CFLAR,VAX2,ABCG1,PDE4DIP,PPP6R2,KIAA0586,C2CD2L,RCAN1,DTNA,SUGP2,TNK2,BAIAP2,CELF1,INPP5K,SRCAP,CNTRL,LSS,NFYA,PMP22,RAD51D,GTDC1,TCP11L1,FUZ,BTBD7,CDK19,MCF2L,AGTPBP1,ZNF74,SPHK2,REEP1,SEMA3B,MPPE1,ST7,UBE3B" Drug 3013_DN Propantheline bromide [50-34-0]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG3,AZGP1,SYNJ1,SYNJ2,CACNB4,SLC16A4,CLGN,SOCS6,B4GALT6,QKI,SIPA1L1,ZNF337,HIPK3,MBNL2,PLXNC1,TUBD1,PIPOX,PDLIM5,CAMKK2,OGA,INPP5K,RAB40B,PRUNE2,ELOVL5,AFF1,NF1,PPP5C,TMEM231,CLIP1,PPM1E,FAM214B,CCDC88A,ZNF415,TPM1,TRO,FLRT2,XRCC4,SEMA3B,PCBP4" Drug 5064_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADCY6,ADORA2A,ADRA1B,AMPH,AMT,APBB2,ATP2B2,ADGRB2,NRP2,CFLAR,CAPN3,ENTPD2,CRLF1,ARHGEF4,DAPK3,BRINP1,HEPH,DMPK,COQ7,RCAN2,ETV1,REEP2,EFCAB2,ALDH1L1,GRM8,KCNF1,MBD1,NPTX1,PFKFB4,C19orf57,MINDY2,PRKCB,GRAMD1C,DCHS2,SNCA,SP4,TEK,TUBB1,VGF" Drug 3753_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,ADORA1,CACNA2D1,SYNGR3,LARGE1,CDO1,COL9A3,SNCAIP,CNTNAP2,SPOCK2,DBT,PLXNC1,ING4,CPLX2,SRCAP,RUNDC3A,GNAL,C2orf72,KCNN1,KCNQ3,MEF2C,ADAM22,SAMD14,NPTX1,CDK18,GPR85,PLXNB1,CEP41,PTN,PTPRH,PTPRO,RASGRF1,ZNF821,CPEB3,PREX2,DOP1A,TRO,FLRT2,KCNAB1" Drug 3228_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,BIN1,EPS15L1,WHRN,SMARCAL1,LRIG1,CDON,OPTN,EIF4G2,HSD17B14,MTSS1L,SRCAP,POLL,GNG4,CACFD1,GRM8,KCNQ3,LMO2,MPP2,SLC11A2,CCSER2,RETREG1,PRKAR1B,RGS12,EMID1,NLGN1,FAM214B,KDM4C,UNC5B,TROVE2,PLCB1,TNS2,PCDHA5,THRA,ZKSCAN5,VGF,KCNAB1,MARCH8,GAN" Drug 5410_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ALK,AQP6,CDC14B,ARHGDIG,ADAM23,MPDZ,BAIAP3,LDLRAD4,CA12,CAMK2B,CBFA2T2,CLGN,ARHGAP22,GSDME,CDON,AASS,FHL1,SIGLEC8,ALDH1L1,LIG4,SMAD1,MAN2A2,MSR1,NNAT,NOVA2,P2RY1,TMOD2,LRP12,PPP5C,PRKCB,SLC22A4,SMARCD3,DOK5,DOCK9,GPR161,ZNF34,PIK3R5,EVI5,PARP11" Drug 6992_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADRA1D,SEMA6A,AMPD3,BIN1,SHROOM2,PDE8B,NCOA1,CFLAR,CRY2,NCOR2,CSF1,PDE4DIP,CTH,RIMS2,GPRASP1,KIAA0586,GIT2,SGSM2,TMCC2,MED12,CDON,EIF5,ENO2,MTSS1L,KAT8,OGA,DISC1,COPS8,TJAP1,MAP4,PTN,CCDC40,SMARCD3,RBM34,ARHGAP26,SPTAN1,BCL2L13,LMF1,ZNF74" Drug 3824_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ARRB2,ZSCAN18,ATP6V0A1,ADAM23,BMP7,SCAPER,CFAP410,SYNGR3,CRLF1,NDST3,AATK,RGS6,PLXNC1,LRRC17,FOLR2,PDLIM5,ERGIC3,DISC1,GFER,PADI2,ICA1,IRF8,SMAD1,KITLG,MSI1,MYT1,GPR85,PDZRN4,RASGRF1,RET,CCDC102B,RTN1,SEMA6D,SH3BP2,CNKSR2,SLA,SPTAN1,HIRA,VIPR2" Drug 6968_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASPHD1,SCAPER,GYG2,KYAT1,ARHGEF1,QKI,DOCK4,RCAN1,EGR3,EIF5,RRAGB,FAM198B,ZNF589,FHL1,GAD1,INPP5K,MSL3,ELOVL5,INPP5B,SMAD1,MMP16,NPR2,NLE1,GTDC1,FNDC3A,SYBU,CCDC88A,SLC22A4,RBM34,ZHX3,UNC5B,NXT2,VPS13A,MCF2L,TRIM2,CHST8,TPM1,MAP3K12,ST7" Drug 3163_UP Glibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADRA1D,DDO,CDC14B,CDK13,ALDH7A1,SYNJ2,CACNA1I,FOXN3,LY86,PITPNM3,SNPH,MFAP3L,RUSC2,RCAN1,MBNL2,ACSL4,FGF12,EFCAB2,SIGLEC8,RUNDC3A,GRM2,IGF1,KPNA5,TAGLN3,ZNF862,NOVA2,P2RX7,PPP5C,PTPRB,SH3GL3,CNKSR2,FAIM2,TBCEL,RPGRIP1L,SZT2,PCDHA5,TRIO,XRCC4,ADAMTSL3" Drug 441_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "CDC14B,ARRB2,SLC4A4,NRP2,CACNA1I,CAMK2G,CBFA2T2,ARHGEF2,GREB1,B3GAT3,DPP6,RCAN1,DTNA,STX2,TBC1D16,TRMO,ALDH1L1,RAB40B,ICA1,JAK2,MAP4,MYO6,NPY,NTRK3,PLXNB1,FSD1,PTH1R,RNASEL,SH3GL3,ELMO2,CDK5RAP2,SNAP25,RGL1,EXOC7,TBL1X,TRPM2,UCHL1,NDRG4,SPHK2" Drug 5479_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,FAM131A,SLC4A4,ATP2B2,SYNJ1,CFAP410,FOXN3,WHRN,COL9A3,SLITRK5,RIPOR2,ARHGAP24,NCALD,IGSF6,OLFM1,PRELID3A,CNTRL,IPO5,MMP16,NELL2,NTRK2,WDR25,BEND5,ZDHHC14,KLHDC8A,ROBO1,SLC2A5,COA1,PDZD2,IQSEC2,SYT5,EXOC7,CRTC1,THRA,HEY1,TNS1,PIK3R5,LMF1,WIPF1" Drug 7533_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA1,FAM135A,APOC1,MARK4,CCNT1,FOXN3,TAOK2,DTNA,ELN,DLC1,ZNF589,FLNC,KCNMB4,GPER1,RNFT2,RASSF8,NXPH3,ATXN2L,KCNF1,KCNH2,NELL2,CNOT4,NPR2,PALM,PCDHGC3,PCDH9,RETREG1,MINDY2,PPP5C,PRPH,GDPD2,RFX3,KCTD17,FAM214B,SLC44A1,R3HDM1,TRO,FAM155A,REEP1" Drug 6144_DN Piretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASIC1,MTUS1,APC,ARHGEF7,SGCE,RAB33A,CREM,CRMP1,ARHGEF10,CELSR3,MRNIP,ZNF589,FHL1,SEPT9,ZNF276,POLL,SPACA9,PDE4B,PIK3R1,CCSER2,NLE1,RIPOR1,TCP11L1,MAP6D1,MRAS,FAM102A,SPATA7,SS18,SYN2,EXOC7,ADGRL3,TNS2,CHST8,HIRA,VIPR2,LMF1,CLIP2,KCNAB1,MARCH8" Drug 3540_DN Quinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AK2,AMPD3,BIN1,PPP4R4,PDE8B,RIPK1,KIF1A,CAMK2G,RAB28,NECTIN3,CREM,CRY2,RUSC2,NCALD,ANKMY1,BAIAP2,USP19,CNTRL,SPACA9,LMO2,MAPT,MIA2,ADAM22,NEK1,PDPK1,PRKAR1B,SEMA6D,SBF1,ANKRD6,ABLIM3,KIF13A,THSD1,ELOVL4,PHLDB1,VPS13A,ASTN2,ZEB1,WIPF1,EMSY" Drug 1798_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "TRMT9B,CDC42BPA,BLM,LDLRAD4,CBFA2T2,ARHGEF2,LARGE1,PLAA,NRG2,VCAN,CDON,EDNRA,FEM1B,COQ7,TRMO,TPK1,DLL3,GAD1,SEPT9,GCNT2,ARFIP1,GPR37,CNTRL,ITGA7,KPNA5,MATN3,CLDN11,PDE1C,RAD51D,FNDC3A,PEX26,SLC14A1,ZHX3,UNC5B,LHPP,NXT2,TRIM2,THRA,CABIN1" Drug 4102_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "TRMT9B,APC,ARHGDIG,RASL11B,N4BP2L1,RGS9,BAIAP3,CAMK2A,CAMK2B,CBLN1,CHRNA4,NRXN3,STOML1,CSF1R,DBT,SGSM2,AFF2,OGA,LYVE1,ICA1,SCIN,KCNN1,AFDN,P2RY13,NF1,ENPP2,PPP1R1A,MARCH1,CCDC40,SCN2B,MRAS,ASAP3,ARHGAP26,SPTB,ARC,KLHL4,AMACR,EVI5,KCNAB1" Drug 7218_DN Avermectin B1 [71751-41-2]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "MTUS1,CDC42BPA,CFLAR,KRIT1,LHX2,MAP4K4,LRIG1,SOCS5,PDE4DIP,CTH,PPP6R2,DBT,NR1D2,SUGP2,IRAK4,ATP2C1,CSPG5,GHR,ZNF276,TXNL4A,ICA1,IL6ST,MBD1,MMP16,NCAM2,PRKAR1B,RIPOR1,NKAIN1,RXRA,FAM192A,SUPT20H,ZNF430,MAPKBP1,ZSWIM8,CLASP2,STXBP1,JMJD6,MPPE1,GAN" Drug 5829_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "PPFIA3,CAMK2G,CCNT1,ARMC8,WHRN,BAG4,DBT,KLHL3,EIF5,EZH1,ST3GAL6,FECH,CINP,TRAF3IP2,DENND2A,TMEM8B,DISC1,ARFIP1,PRRC2B,INPP5B,MEIS1,MAPK7,CNNM2,SAMD9,FAM102A,PDZD2,ERC1,SPTAN1,ZBTB43,NXT2,ELOVL4,EXOC7,TNS2,TIAM1,TK2,TRIO,LMF1,KLC2,RNF170" Drug 4485_DN Riboflavine [83-88-5]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ALK,AMT,MARK4,ZBTB10,WHRN,NRG2,AATK,VCAN,RUSC2,PARD6A,DTNA,PLEKHA1,RGS17,COQ7,CDKL3,SCML2,FGFR1,IQCG,FAM49B,POLL,MUM1,SHISAL1,SCIN,KIF2A,MAPT,PRKAR1B,RIPOR1,FAT4,GAL3ST4,ASAP3,SLC4A3,PPP4R3A,ZNF667,KDM4C,VPS13A,SYNE1,ZNF24,NDRG4,MAP3K12" Drug 3815_UP Methimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,LTBP4,FAM135A,APAF1,CACNA1G,SUSD5,DTNB,EDIL3,EDNRA,MBNL2,EGR3,EPB41,ETV1,NEU3,POLL,GPD1,GRM2,SOX21,MATK,KITLG,NF1,CDK18,PDE4A,PTPRN2,RASGRF1,RGS4,KLHL11,SMPD3,CPEB3,FAM214B,SLC11A1,SSTR2,TAL1,TPM1,TPM2,CHST5,UCHL1,SPHK2,JPH3" Drug 6502_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "DOC2A,TRMT9B,APC,PPFIA3,CFLAR,SYNJ2,GYG2,PLAA,SH2B1,CSNK1E,SIPA1L1,PDE4DIP,FAM169A,GIT2,DBT,CDON,DISC1,AHDC1,GRIK5,INPP5B,KCNH2,KHK,IPO5,SLC25A23,PPP5C,TMEM104,KIF16B,AMBRA1,PKNOX2,ZKSCAN3,ZHX3,ZC3H13,TROVE2,FBXW11,RPGRIP1L,VGF,ZNF74,HPS4,ST7" Drug 6030_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "PPFIA3,ZBTB10,CFLAR,SYNJ2,KRIT1,SLIT2,RAB28,QKI,COL4A5,CREM,PDE4DIP,FAM169A,GIT2,FBXL5,DTNA,EDNRA,ING4,STX2,KAT8,BAIAP2,COPS8,HTATSF1,HNMT,PRODH,ZDHHC14,ZNF821,FBXO11,SLC22A4,SPATA7,KIAA0930,TRIM2,CHST8,TIAM1,PARD3,TRIO,REEP1,EVI5,HPS4,MPPE1" Drug 5416_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "KDM5D,NDRG2,AP2A2,BEGAIN,APAF1,PRX,CACNA1I,CA4,CNTFR,WHRN,SNCAIP,ARHGEF10,SOCS5,GREB1,TMCC2,DNM1,DMPK,CDON,AASS,REEP2,FGFR1,AGAP2,GAD1,GLI2,GLYR1,PRRC2B,RASSF8,NCKAP1L,ICA1,MAP4,MYO7A,PLCD1,RGS12,SLC2A5,OGDHL,ZC3H13,RBM26,SYT5,EPM2A" Drug 2492_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SPARCL1,BEGAIN,ANK2,APC,PPFIA3,ATP6V0A1,NRP2,CALB2,CAPN3,SLC16A4,CDH2,CRLF1,AKAP6,RCHY1,CREM,CRMP1,EDNRA,HIPK3,RASGRP2,STX2,KHDRBS3,NEU3,HPGDS,GRIK5,MAP4,TAGLN3,NPTX1,PFKFB2,CEP41,STUM,ZHX3,SPTAN1,PHLDB1,DNMBP,CDK20,FAM155A,SPHK2,KCNAB1,JPH3" Drug 1574_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,ANK2,ARNTL,ARRB2,RIPK1,CLDN10,PPP1R16B,ARHGAP32,C2CD2L,MED12,ANKRD46,EPB41L2,FGFR1,TRMO,MPP6,ALDH1L1,COPS8,DBF4,PADI2,ITGAM,KCNN1,MAP4,MBD1,AFF1,NEFH,SLC25A23,LRP12,PTK2,RPS6KA2,KBTBD4,KDM4C,SPART,EXOC7,TBL1X,VAV1,TFIP11,EVI5,ACTR3B,AAAS" Drug 7373_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "RALGAPA1,AMPH,CDC42BPA,CDC14B,CFLAR,CACNA1A,CAMK2A,AKAP5,CNTNAP2,ARHGAP24,TBC1D5,DTNA,DUSP9,FCF1,FGFR1,AGAP2,LPAR4,IL12A,KITLG,MYO7A,NF1,CNOT4,CLDN11,PTPRH,PTPRN2,RIPOR1,PPP4R3A,KANSL3,IZUMO4,IQSEC2,ZBTB43,SYN2,SYT1,GPR161,THRA,ZKSCAN5,LMF1,SEMA3B,KCNAB1" Drug 336_DN nitrendipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "KDM5D,ADCY6,LTBP4,BIN1,MTMR2,BAIAP3,HIP1R,AKAP12,PDE4DIP,TSPAN5,HSD17B14,F5,ZMYND10,FOLR2,KHDRBS3,NEU3,MALT1,STON1,FAM107A,IGF1,KHK,MBD1,MYO7A,SATB1,SH3BP2,FERMT1,KDM4B,MYCBP2,THSD1,ANKRD12,EXOC7,TRIM2,DOCK9,CDH22,TRIO,TUBB1,LMF1,WNT7A,MPPE1" Drug 2373_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA1,APBB2,ATP2B2,BMP7,SCAPER,CACNA2D1,ABCG1,PPP1R16B,RIPOR2,MFAP3L,FGFR3,KHDRBS3,SIGLEC8,ALDH1L1,ADAM28,CACFD1,ATXN2L,ICA1,KHK,TAGLN3,SLC11A2,MINDY2,CNNM2,PTPRH,GAL3ST4,RNASEL,EPN2,LIMS2,FAM214B,ZHX3,ZSWIM8,RBM26,TROVE2,DNMBP,TRIM2,CRTC1,R3HDM1,REEP1,EMSY" Drug 4216_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "CFLAR,ARHGEF7,KRIT1,CNOT8,QKI,BAG4,VCAN,DBT,EXOG,DTNA,RGS17,ETV1,FER,ANKFY1,TRMO,FAM69A,LIG4,TAGLN3,CCSER2,RETREG1,PLCD1,STRN3,ZCWPW1,FBXO11,TMCC1,SPTAN1,TROVE2,SAMSN1,NXT2,ARHGEF9,PLCB1,ZNF34,RUNDC3B,SSBP2,UBTF,NDRG4,KCNAB1,MPPE1,SMIM8" Drug 7451_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,AP2A2,LTBP4,APAF1,MARK4,CAMK2G,ARHGEF2,STOML1,NCOR2,RCAN1,HIPK3,FAM198B,FECH,FGF12,CAMKK2,CGREF1,OGA,TRAF3IP2,SYT17,GRB10,RNFT2,ADAM22,LYRM9,NF1,CNOT4,LRP12,PRKAR1B,PTN,RIPOR1,NKAIN1,SBF1,CCDC88A,TROVE2,PLCB1,EXOC7,RPGRIP1L,PCDHA6,CDK20,LAT2" Drug 3926_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,ADORA1,ADRA1B,ADGRF5,BEGAIN,DLGAP1,CRY2,SNCAIP,DNAH9,RCAN2,ERCC2,ZNF391,PTK2B,AFF2,FYN,CHL1,GFER,HPGDS,GRIK5,SHISAL1,MMP16,MYCN,PCBP3,CEP41,PTCH1,CCDC40,C1orf54,GAL3ST4,SATB1,ZFP2,STUM,ASAP3,CCDC88A,SNCA,NMNAT2,CLSTN2,SSTR2,JMJD6,TUBB1" Drug 3846_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,CDK13,C5,BAIAP3,TAOK2,CSF1,CNTNAP2,DCAF4,GIT2,ZNF804A,SLC12A6,TOM1,ZNF589,PRELID3A,CACFD1,MAP4,MMP16,ADAM22,NPR2,PLEC,PLXNB1,MAPK7,SNRK,ZSCAN2,ZDHHC14,ZMAT4,TRIM68,TCP11L1,EMID1,SBF1,SH3BP2,LIMCH1,IQSEC2,SYN2,EXOC7,KIAA1107,TNS1,LAT2,EMSY" Drug 4367_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,ADRA1D,AP2A2,BIN1,GYG2,CFAP410,KRIT1,CLGN,SOCS6,AKAP12,ZNF804A,MFAP3L,DMPK,ANKMY1,FECH,RUNDC3A,TDRKH,GPER1,DIDO1,GRIK5,BTN2A1,PADI2,MMP16,CNOT4,SLC25A23,CCDC40,GSTCD,TCP11L1,FBXO11,TMCC1,SPTAN1,IQSEC2,CAMTA2,EXOC7,PCDHA6,AP4E1,ZNF106,PLPPR2,KAT6A" Drug 4292_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SPARCL1,PKP4,ZSCAN18,SLC4A4,NRP2,BMPR1B,BAIAP3,TAOK2,EPS15L1,RAB28,FAM189A2,VCAN,SHANK1,DTNA,HIPK3,REEP2,FGF1,PDLIM5,ZNF44,GPER1,GRIK5,CACFD1,IL6ST,AFF1,CNOT4,PIK3R1,PPARA,ELOVL2,ZCWPW1,RET,RGS4,DZIP1,HECW1,KDM4C,MCF2L2,CRTC1,VSNL1,LAT2,SLC17A7" Drug 5278_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SPARCL1,LTBP4,OGT,KSR1,CACNA1I,TAOK2,PICK1,SEC14L5,SPOCK2,DMPK,RASGRP2,NCALD,CORO2B,FGFR1,GATM,GFER,AP4S1,ATXN2L,MID1,ZNF862,CLDN11,PLTP,PDZRN4,LRRN3,KCTD17,FAM214B,PKNOX2,MAPKBP1,HECW1,ARHGAP26,DMXL2,DOCK9,R3HDM1,AMACR,UBE3A,EVI5,SLC17A7,KCNAB1,PLSCR4" Drug 4393_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASIC1,LTBP4,BEGAIN,SEMA4G,RASL11B,SLC4A4,BAIAP3,LDLRAD4,CFAP410,RUNX1T1,CDO1,TPP1,VCAN,SPOCK3,EGR3,RASGRP2,HPCAL4,GRIK5,IRF8,MYCN,NF1,PDE1C,C19orf57,SAMD9,PTPRB,ENOX1,KCTD17,MRAS,SLC2A5,KANSL3,SNAP25,HECW1,ZNF423,SPTB,ATP10B,ICAM5,TNS1,TRPM2,DNALI1" Drug 6194_DN genistein; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AMT,GAS7,APOC1,ZSCAN18,ATP2A2,ADAM23,BMP7,SYNJ2,SCAPER,LDLRAD4,STOML1,HOMER3,TBC1D5,DTNA,COQ7,RASGRP2,CDKL3,ANKMY1,DLC1,FHL1,DIDO1,ITGAM,KCNN2,NLE1,PLCB2,PPP3CC,ZNF493,RET,PLPPR3,SLC2A5,ZNF667,SPP1,KDM4C,DDN,CUX2,TNS1,CDK20,HPS4,UBE3B" Drug 3784_DN Vincamine [1617-90-9]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NME5,LTBP4,BCHE,BMP7,CBS,SCARB1,LRRFIP1,PLEKHB1,NRXN3,ABCG2,EIF4G2,TUBD1,ETV1,F5,FGF1,OGA,DISC1,GFER,POLL,KCNB1,LSS,NF1,NFYA,NPR2,PCBP3,PDE4D,SERPINI1,ZSCAN2,ACSS3,SUSD4,RGS4,FNDC3A,OGDHL,SOX15,SP4,THSD1,TRIM2,CABIN1,SENP7" Drug 4577_DN Prednisone [53-03-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "EPB41L5,ARHGDIG,ADGRB2,BAIAP3,CBFA2T2,TPP1,NRG2,PDE4DIP,RUSC2,KLHL3,CHRDL1,CDON,FEM1B,EGFR,PLXNC1,STX2,FGF13,USP19,TDRKH,ELOVL5,MAPT,PPP5C,PTN,TCP11L1,FNDC3A,ZHX3,NXT2,MCF2L,KIAA1107,CRTC1,THRA,TIMP4,AMACR,VGF,VIPR2,WIPF1,XRCC4,KCNAB1,TIGD6" Drug 5211_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADCY6,C1QTNF3,ALDH7A1,USP2,CBFA2T2,PICK1,CRMP1,CNTNAP2,RUSC2,FCF1,MBNL2,EPB41L2,MTSS1L,FGF12,SEMA4D,PDLIM5,CSPG5,GAD1,GLYR1,PCLO,KPNA5,SMAD1,MAP4,KITLG,ZNF862,PNMA8A,ZNF821,CNKSR2,KANSL3,PKNOX2,CCDC88A,LIMCH1,JMJD6,ARC,PCDHGA10,PCDHA5,XRCC4,NT5M,TIGD6" Drug 2155_DN Vitexin [3681-93-4]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ABHD6,NDRG2,APOC1,BMP7,USP2,HIPK3,ING4,ELN,ETV1,FHL1,GAA,GATM,USP19,POLL,KCNMB4,MAP4K5,GIT1,MX1,MYT1,SLC11A2,OGG1,PLCD1,CNTLN,ZSCAN32,RAD51D,ZDHHC14,SH3BGR,PPM1E,PREX2,SLC11A1,IZUMO4,TSPYL2,JMJD6,PLCB1,PDLIM2,TCF4,TPM1,MPPE1,PHTF2" Drug 2281_DN Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "KCNAB2,APC,DNAH17,ALDH7A1,CFLAR,CA4,MAGI1,LYPD1,RCAN1,EGFR,PLXNC1,EFCAB2,TPK1,SRCAP,GLYR1,RAB30,STON1,INPP5B,MPP2,NF1,PLCD1,PTN,KLHDC8A,CCDC25,TCP11L1,SUPT20H,SH3BP2,IQSEC2,CLSTN2,TTBK2,PLCB1,NSD1,CRTC1,BHLHB9,VGF,KCNK12,SLC30A3,KCNAB1,TIGD6" Drug 2676_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "MTUS1,PPP4R4,CASK,ARRB1,RGS20,USP2,CLGN,B4GALT6,EPS15L1,QKI,ZNF337,DGKG,HIPK3,EGFR,TNK2,RASGRP2,ZNF589,FER,GATM,SYNPO,MEF2C,MYO7A,PLCD1,PURG,MAPK7,GRAMD1C,SUGCT,ZNF821,KIF16B,CPEB3,SLC11A1,RPGRIP1L,CHST8,ZNF34,TK2,TRPS1,LMF1,EPM2A,PHTF2" Drug 7261_UP Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "APC,ZBTB10,ARHGEF7,SCAPER,CFAP410,CBFA2T2,SRSF11,SOCS6,PLEKHB1,CSF1R,PDE4DIP,DZIP3,MFAP3L,E2F5,EDIL3,IRAK4,COQ7,CDKL3,TRMO,PDLIM5,GLI2,GUCY1B1,FAM69A,KPNA5,NNAT,SETD4,PFKFB2,MAPK3,NCBP3,TRAPPC13,AMBRA1,ELMO2,KDM4B,SS18,PHLDB1,SYT1,DOCK9,HPS4,RNF170" Drug 1497_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "C1QTNF3,SRPX,APLP1,PLA2G4C,MARK4,NRP2,HAP1,CAMK2A,CCK,DCLK1,CPS1,HAPLN1,GREB1,EIF4G2,ERCC2,ZNF589,CSPG5,RUNDC3A,RAB30,RASSF8,INPP5B,KCNH2,MMP16,MYO7A,CLDN11,SEPT4,CEP97,C1orf54,RPS6KA2,PPP4R3A,COA1,RPGRIP1L,CHST8,PIK3R5,FAM155A,KCNK12,NDRG4,NT5M,RNF170" Drug 2242_DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "BIN1,ATP6V0A1,SYNJ2,HAP1,ARHGEF1,CBFA2T2,RAB28,AKAP7,SMARCAL1,SEC14L5,MFAP3L,TMCC2,CDON,FER,FHL1,TMEM8B,POLL,GRB10,SPACA9,ADAM22,CNOT4,CDK18,KCTD15,PRKAR1B,PTN,DCUN1D2,TCP11L1,EMID1,SEC14L1,PREX2,SNCA,LHPP,CLSTN2,THSD1,PLCB1,ARC,KAT6B,NDRG4,EMSY" Drug 5611_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADRA1D,NME5,SEMA6A,APOC1,CFAP410,SCARB1,FOXN3,ABI3BP,PDE4DIP,FAM169A,TBC1D5,KIAA0586,MFAP3L,OPTN,MBNL2,EIF4G2,COQ7,RRAGB,SCML2,FER,GLYR1,BTN2A1,INPP1,KPNA5,LSS,KITLG,SLC11A2,SLC25A23,PLXNB1,FSD1,PPP5C,ZSCAN32,SLC22A4,ST5,TTBK2,PLCB1,TNS2,CABIN1,TRIO" Drug 2029_UP Famotidine [76824-35-6]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AK2,ARRB2,N4BP2L1,BCL7A,NRP2,CA12,CAPN3,CHN2,CNOT8,FAM189A2,C2CD2,SPOCK2,TMCC2,DCTN4,CAMKK2,IRAK3,MAN1B1,ELOVL5,HNMT,MBNL1,GIT1,NF1,SETD4,PPM1B,PTPRE,CCDC40,SUPT20H,FAM102A,AMBRA1,WDR47,KBTBD4,ELMO2,LMO3,CEP68,FBXW11,TBL1X,HIRA,ZNF24,UPF3A" Drug 3622_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ADORA1,ADRB2,MARK4,SLC2A11,AZGP1,ST3GAL5,GYG2,CAMK2B,USP2,SULT4A1,AATK,CSF1,CSF1R,GIT2,EDIL3,AASS,IGSF6,PIPOX,FER,FGFR1,SCARA3,DLL3,GPR37,IGF1,KHK,MGAT3,NF1,PDE1C,PLXNB1,PNMA3,SAMD9,CCDC40,ASAP3,PKNOX2,SLC11A1,HECW1,WSCD1,WIPF1,KCNK12" Drug 1919_DN Tolnaftate [2398-96-1]; Down 200; 13uM; PC3; HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "APAF1,APC,GAS7,NCOA1,BACH1,KRIT1,CCNT1,FOXN3,CLCN3,QKI,AKAP12,NCOR1,CSNK1G3,CTH,HDAC9,ZNF337,EZH1,ACSL4,AMOTL2,SEC23B,MPP6,TRAF3IP2,CRCP,GPR12,GRIK5,KTN1,CYBC1,TMEM231,TCP11L1,SH3BP2,SH3GL3,R3HDM2,KBTBD4,SLC22A4,SYT1,CLASP1,KLC2,SPHK2,ZNF189" Drug 2637_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "SYN3,AGT,ALCAM,BIN1,CDC14B,MARK4,ATP6V0A1,GYG2,HAP1,TAOK2,RAB28,WHRN,ABI3BP,CRY2,VCAN,CTH,RIMS2,RUSC2,C2CD2L,TMCC2,MBNL2,HSD17B14,APC2,GCNT2,INPP5B,NOVA2,RETREG1,SCN8A,FNDC3A,SLA,KDM4C,ERC1,SPTAN1,SPTB,KIAA1107,OBSL1,CHST8,ZNF45,FAM13C" Drug 2536_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "AP2A2,CDC42BPA,SLC4A4,THSD7A,CHN2,CRMP1,CRY2,DCAF4,SEC14L5,SNPH,DGKG,TMCC2,EDNRB,CNNM1,C3orf18,HSD17B14,ERBB2,TLR7,CORO2B,ZNF276,RAB30,SCIN,KIFC3,MEF2C,MMP16,MYCN,PDE4D,PFKFB4,PGAM2,MAPK10,RIPOR1,CCDC40,ZMAT4,KDM4B,HECW1,SPTAN1,TROVE2,MCF2L,ZNF74" Drug 2030_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "RALGAPA1,ACTN1,NDRG2,APBB2,CDK10,SYNJ2,MTMR3,LDLRAD4,SLC25A14,CAPN3,CD86,SLIT2,RAB33A,DCAF8,KAT8,OLFM1,SRCAP,GDF9,USP19,LILRA2,HNMT,ICA1,TJAP1,KIF5A,LSS,NINJ2,TRIM68,TCP11L1,GALNT10,ELMO2,IFT122,TMCC1,DOK5,ZBTB43,TSPYL2,CLASP1,PHF24,KAT6B,ACTR3B" Drug 4984_DN beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "ASPHD1,AMT,CFLAR,CA12,B4GALT6,TPP1,QKI,CREM,SIPA1L1,PDE4DIP,FAM169A,C2CD2L,MED12,EDNRA,CELSR3,MRNIP,COQ7,VPS26C,SYT17,GRIK5,SLC2A6,MBD1,GIT1,ADAM22,NF1,LRP12,TMEM104,SH3BP2,PPM1E,FNDC3A,PREX2,SLC6A8,BTBD7,LIMCH1,VPS13A,SLC44A1,TK2,EVI5,PHTF2" Drug 2754_UP Dacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.17E-04 1.00E+00 4.21E-03 4.74E-02 39 198 "NDRG2,APLP1,CALB1,RCBTB2,FOXN3,LHX2,PHF14,ARHGEF4,SEC14L5,TMCC2,DTNB,EDIL3,EDNRA,PLXNC1,EIF4G2,ETV1,OGA,GABRG2,POLL,GRIK5,GSN,IL6R,KIT,MAP4,PDPK1,TMOD2,ELOVL2,FAM184A,KCTD17,PKNOX2,HECW1,IQSEC2,CAMTA2,PHLDB1,NSFL1C,JMJD6,TBCEL,CRTC1,DICER1" Drug 1159_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.29E-04 1.00E+00 4.33E-03 4.88E-02 35 172 "NDRG3,NDRG2,MTUS1,CFLAR,ST3GAL5,GYG2,CD86,RAB28,RCHY1,CREM,SIPA1L1,KIAA0753,RCAN1,FAM13A,MBNL2,VPS13B,F5,FHL1,ATP2C1,OGA,MPP2,PDE4B,PDE4D,NECAB2,MBOAT7,PRKACB,ZSCAN32,HSPA4L,ZC3H13,SPTAN1,NPDC1,MPPE1,PHTF2,FXR1,SENP7" Drug ctd:C004648 testosterone enanthate CTD 4.29E-04 1.00E+00 4.33E-03 4.88E-02 92 575 "NDRG2,ADCY6,USP31,MTUS1,OSBPL8,SRPX,PDE8B,EIF4G3,MPDZ,DDR1,SPAG9,CBR1,USP2,RGN,SCARB1,CLCN3,FAM149A,PDE4DIP,PHF14,TCAF1,HEPH,EDNRA,EDNRB,SUGP2,MBNL2,EIF4G1,PLEKHA1,ST3GAL6,SEC23B,PCYOX1,SYNCRIP,SMC2,TRIM16,ZNF44,PCDH17,PPARGC1A,DHRS4,HTATSF1,FERMT2,PRUNE2,AP4S1,MUM1,IFI16,IGF1,IL6R,IL6ST,JAK2,LIMS1,MAPT,MX1,MYH3,MYO9A,NEK1,CNOT4,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,GPSM2,STRN3,PRKAB2,PRKACB,MAPK3,PTN,PTPRD,USP47,C1orf54,SEC14L1,ABLIM3,SNCA,SNRPN,USP33,ERC1,DIP2A,PRRC2C,ASTN2,TCF4,ZEB1,CBX5,PARD3,ELP5,TTC3,SGK3,FLRT2,USP1,WIPF1,ZFP37,ZIC1,ST7,ADAMTSL3,FXR1" Drug CID000656673 chromomycin A3 Stitch 4.41E-04 1.00E+00 4.45E-03 5.01E-02 24 103 "APAF1,DYNLL1,BLM,CACNA1A,CACNA1B,AHCTF1,DYNC1I1,ENO2,PPP1R1B,AHDC1,PPARGC1A,TCERG1,PACSIN2,IGF1,OGG1,ABCB1,QDPR,FBXW7,ATXN7,FOXRED1,ZEB1,UBTF,PRTFDC1,JPH3" Drug 6728_UP Betamethasone [378-44-9]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ADORA2A,ALK,SCARB1,CACNA2D2,FOXN3,CNTNAP2,FAM131B,MFAP3L,HIPK3,ETV1,FGF12,DCTN2,CAMKK2,OGA,GATM,ALDH1L1,RUNDC3A,GNAL,PRUNE2,ELOVL5,IL6R,MATN3,KITLG,AFDN,ADAM22,MX1,MYO7A,TMEM231,ZMAT4,RGS12,SLA,SLC11A1,ZHX3,ZC3H13,SPTAN1,GPR161,TK2,PARP11" Drug 5812_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "CDC42BPA,CDK10,SEMA4G,CFLAR,CNOT8,ARMC8,CPS1,CREM,ENTPD4,AKAP12,SIPA1L1,CTH,DCAF8,GIT2,PITPNC1,ARMCX2,CDON,EDNRA,TAGLN3,NF1,SMOX,GSTCD,ZNF821,SLC8A1,ELMO2,IFT122,TMCC1,SYN2,TACR1,TCF4,DOCK9,OSBP2,VGF,SEMA3B,SLC17A7,MPPE1,PLSCR4,EPM2A" Drug 7218_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "AK2,AMPD3,APC,NUMB,RGS9,SYNJ1,LDLRAD4,CACNB4,RCHY1,SEC14L5,SLC12A6,DTNA,CNNM1,DLC1,FER,FYN,SRCAP,GRB10,GRM8,ELOVL5,MATN3,MITF,MPP2,ZNF862,NELL2,PFKFB4,NLE1,C1orf54,KHDRBS2,ASAP3,SYBU,KANSL3,SNCA,UNC5B,WSCD1,PCDHGA10,SLC44A1,TPM1" Drug 4094_DN Decamethonium bromide [541-22-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "MTUS1,AMT,CDC42BPA,KCNAB2,NCOA1,ST3GAL5,MYRF,IL33,CFAP410,KYAT1,SCARB1,SOCS6,CRMP1,BRINP1,RUSC2,SGSM2,ING4,MTSS1L,STX2,SPEG,SCML2,CINP,SEPT9,LMO2,TM6SF1,RETREG1,MAPK7,PRPH,PTPRB,MAPK12,CSRNP3,DZIP1,PREX2,TK2,R3HDM1,HIRA,WIPF1,SH3GLB2" Drug 901_UP 5114445; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "APBB2,ATP2B2,KSR1,LDLRAD4,CA4,SRSF11,PLEKHB1,ARMC8,COL9A3,CDON,RASGRP2,MTSS1L,ST3GAL6,AGAP2,EFCAB2,ERAP1,MSL3,GNG4,STON1,CNTRL,MGAT3,ADAM22,GRAMD1C,ZSCAN2,KCTD17,RASA3,ZFP30,SH3BP2,FAM214B,THSD1,SYP,ASTN2,RIMBP2,TRIO,RUNDC3B,TRO,VLDLR,JPH3" Drug 5967_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ADORA1,SEMA6A,BEGAIN,APC,HAP1,USP2,CACNA2D2,RCBTB2,LHX2,CNTFR,EDNRA,OPTN,EGR3,HSD17B14,FYN,ALDH1L1,SRCAP,GNAO1,SPACA9,IL6R,MEF2C,PDE1C,LRRN3,MAPK7,SAMD9,RASGRF1,SALL1,CNKSR2,ARHGAP26,RBM26,THSD1,ZC4H2,TK2,RIMBP2,TNS1,TRPM2,VIPR2,WIPF1" Drug 1207_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ASIC1,ZBTB10,STX16,N4BP2L1,KIF1A,BACH1,IL33,KRIT1,CPS1,AKAP12,ABCG1,VCAN,EXOG,ING4,FAM49B,ERAP1,LILRB4,TDRKH,STON1,DIDO1,ICA1,NOVA1,RETREG1,SUPT20H,ZFP30,FERMT1,ST6GAL1,LIMS2,KDM4D,TSNAXIP1,PBLD,POGZ,TCF4,PCDHGA10,THRA,REEP1,EMSY,PLSCR4" Drug 7538_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "SEMA4G,ADGRB2,MYRF,USP2,WHRN,CREM,AKAP12,CRY2,CSNK1E,CTH,SGSM2,DTNA,POLR1B,CGREF1,B4GALNT1,POLL,ATXN2L,SHISAL1,CNOT4,NLE1,PLCD1,SMOX,CNNM2,PTN,TCP11L1,FAM214B,SMARCD3,ARHGAP26,SPTAN1,PBLD,ELOVL4,TTBK2,CRTC1,TNS1,TPM2,FAM155A,LMF1,FIP1L1" Drug 7092_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ADD1,PPFIA3,CDK13,RIPK1,BACH1,SYNJ2,CAMK2G,FAM189A2,HOMER3,WHRN,CREM,HINFP,NR1D2,RCAN1,DTNA,EIF5,FGFR1,GHR,ZNF276,TXNL4A,GPER1,ICA1,INPP5B,MBD1,NEK1,NFYA,CEP97,CLIP1,EPN2,KDM4B,SOX3,CEP68,ASTN2,ANKRD12,TBL1X,BCL2L13,FZD3,MARCH8" Drug 7104_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ADRB2,LGR5,SHROOM2,CFLAR,AP4M1,MAGI1,RCBTB2,CHN2,CNOT8,HOMER3,NRG2,VCAN,MAMLD1,SCARA3,TRMO,SRCAP,STON1,CACFD1,SLC2A6,SCIN,GIT1,SLC11A2,VPS13C,PTX3,SH3TC2,ZCWPW1,TMCC1,DOP1A,SPTAN1,IQCE,SYNE1,TMEM121,TNS1,TPM2,WNT7A,PDSS2,SMIM8,IFT88" Drug 2831_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "MTUS1,NME5,AMPD3,APC,CFLAR,CAMK2B,USP2,QKI,NCOR2,ARHGEF4,DCAF8,EXOG,SHANK1,EDNRA,MBNL2,ANKMY1,BAIAP2,SCARA3,ZNF44,DISC1,GNG4,LPAR4,MYO7A,ZNF862,MINDY2,ZNF493,ZFHX4,EMID1,PDZRN3,SOX3,IQSEC2,CLSTN2,POGZ,WSCD1,AP4E1,SPHK2,EVI5,ST7" Drug 5575_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ADORA2A,AGT,APBA2,APC,DNAH17,RASL11B,BACH1,RGS11,LDLRAD4,CBFA2T2,WHRN,OSBPL3,PDE4DIP,HDAC9,EXOG,EDNRA,MBNL2,ZNF589,AFF2,SRCAP,GNAL,C2orf72,MSR1,TAGLN3,NOVA1,P2RY1,PFKFB4,PURG,KCTD17,CNKSR2,PKNOX2,ATP10B,TRIM2,SYNE1,HIF3A,HEY1,TRPM2,UCHL1" Drug 6054_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ASIC1,SEMA7A,KCNAB2,ARHGDIG,GYG2,USP2,SEPT7,CNTFR,MFAP3L,DTNA,HIPK3,PDLIM5,COPS8,RAB30,MSL3,CNTRL,GRIK5,IL6ST,KCNN2,MAP4,MMP16,MSI1,ADAM22,NEK1,CNOT4,PCDH9,PTCH1,RNASEL,ZFHX4,TCP11L1,PHLDB1,TRIM2,TNS2,CRTC1,PCDHA6,TIAM1,TK2,REEP1" Drug 1337_UP Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "NDRG2,MYRF,CFAP410,CAMK2G,CCNT1,CHN2,ENTPD4,CSF1R,PDE4DIP,USP6NL,RUSC2,PHC2,NCALD,CELF1,RAB40B,PADI2,MAP4,MATK,ZNF862,NEK1,OGG1,SMIM7,RXRA,SEC14L1,FUZ,FAM214B,MAPKBP1,ZBTB43,ARHGEF9,EXOC7,TK2,ICAM5,TNS1,TST,ZFP37,GDPD5,ST7,NLRP3" Drug 4274_DN Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "MTUS1,CFLAR,SPAG9,KRIT1,FAM169A,PHF14,PUM1,ARHGAP24,DBT,FCF1,ETV1,BAIAP2,ATP2C1,AGFG1,IFI16,IL6ST,JAK2,MAP4,TM6SF1,OPA1,SNX10,STRN3,PPM1B,PPP3CC,PRKAB2,SLC25A36,GSTCD,FBXW7,AP1AR,FBXO11,THSD1,CEP68,ZC3H4,DICER1,TK2,TMPO,ZBTB38,EVI5" Drug 3391_UP Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ASIC1,KIAA1324,ALCAM,CACNA1I,CACNA2D1,CAMK2B,TAOK2,LHX2,EPS15L1,WHRN,RASSF2,TMCC2,EGR3,RASL12,NRN1,PTK2B,DISC1,GPR162,GPER1,JAK2,ADAM22,TAGLN3,MX1,MYT1,NPTX2,MAPK7,ZDHHC14,TRIM68,RET,SLC4A3,KDM4B,ZC3H13,ARHGAP26,UGT8,VLDLR,DNALI1,KCNAB1,AP3B2" Drug 7195_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "DNAH17,MARK4,SLC2A11,ADAM23,CFLAR,SCAPER,SLIT2,QKI,HOMER3,CREM,GIT2,DBT,RUSC2,LYPD1,RCAN1,EGR3,MALT1,MSL3,IRF8,JAK2,KCNN1,KITLG,RETREG1,STRN3,PRODH,SAMD9,ROBO1,BTBD7,SLC22A4,ZKSCAN3,TTC17,SS18,KIAA0930,TMPO,SSBP2,XRCC4,MAP3K12,MPPE1" Drug 5930_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "ASPHD1,GAS7,CDK13,SCAPER,CACNA1I,IL33,CACNA1A,CACNA2D1,CACNA2D2,ARMC8,ABI3BP,VCAN,PDE4DIP,SLITRK5,PARD6A,DMPK,MBNL2,ETV1,SEPT9,GNG4,LPAR4,RASSF8,HNMT,IL6ST,ADAM22,NDP,PTPRN2,ASAP3,SLA,SPTB,LHPP,TIAM1,TIMP4,ZKSCAN5,WNT7A,ZBTB38,NAV3,SLC17A7" Drug 6136_DN Trifluridine [70-00-8]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.45E-04 1.00E+00 4.47E-03 5.03E-02 38 192 "PKP4,LDLRAD4,SLC16A4,TPP1,CRY2,ZNF337,C2CD2L,COQ7,ANKFY1,EFCAB2,SEPT9,INPP5K,ZNF276,DIDO1,CIT,ATXN2L,ITPKB,NINJ2,SLC11A2,PDE4D,PIK3R1,MBOAT7,RIPOR1,ZNF493,RNASEL,MAP6D1,FAM214B,MAPKBP1,SNCA,TMCC1,SPATA7,KIAA1107,FLRT2,PLPPR2,XRCC4,ZFP37,ZNF32,ZBTB38" Drug 1169_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.52E-04 1.00E+00 4.53E-03 5.11E-02 36 179 "AGT,TRMT9B,APC,PPP4R4,CFLAR,LDLRAD4,TPP1,IQCK,SEC31B,CREM,CRY2,RCAN1,FAM13A,MBNL2,CDKL3,F5,OGA,ATXN2L,PDE4B,PDE4D,PLCD1,PMP22,MBOAT7,PRKACB,ZNF493,FBXW7,RPS6KA2,RXRA,HSPA4L,TSNAXIP1,ARHGEF9,KAT6B,TPM1,UCHL1,FLRT2,PLPPR2" Drug 4651_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.52E-04 1.00E+00 4.53E-03 5.11E-02 36 179 "ADCY6,APAF1,LRRFIP1,DCAF4,HDAC4,ETV1,RACK1,FECH,FGFR1,ANKFY1,CAMKK2,CGREF1,ERAP1,DISC1,GPD2,SHISAL1,FAM69A,LAMP2,NACA,OPA1,PLCD1,MBOAT7,SLC14A1,CDK19,SYT1,TACC1,KIAA0930,DICER1,GPR161,ZMAT3,ZNF106,NACC2,CBX5,SLC38A1,FZD3,PHTF2" Drug 839_UP 5224221; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.52E-04 1.00E+00 4.53E-03 5.11E-02 36 179 "GAS7,PPFIA3,RGS20,CARS,ARHGEF2,CLGN,FAM189A2,QKI,CREM,CTH,DAPK3,GIT2,MFAP3L,DTNA,TOM1,MBNL2,BAIAP2,AMOTL2,GRB10,BTN2A1,INPP5B,NRCAM,OXTR,CDK18,PRPH,C1orf54,SUSD4,ZNF821,ZFP30,PPM1E,ERC1,ZNF34,TRIO,BCL2L13,VLDLR,ST7" Drug 6045_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.52E-04 1.00E+00 4.53E-03 5.11E-02 36 179 "AMPD3,CDC42BPA,APC,ATP2B2,ALDH7A1,RGS9,DLGAP1,SULT4A1,COL9A3,SH2B1,HAPLN1,SPOCK3,EXOG,ECM2,HEYL,MBNL2,CAMKK2,FYN,ERAP1,CSDC2,GRB10,HAS2,ATXN2L,SYNPO,ADAM22,PLTP,PTH1R,C1orf54,ZMAT4,SOX15,ZEB1,TRIM2,PCDHGA10,DOCK9,ZNF711,KAT6A" Drug 5079_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,ADORA2A,BBOX1,APAF1,SCAPER,BAIAP3,USP2,MAGI1,CNTFR,IQCK,CREM,CRMP1,VCAN,MFAP3L,TNK2,CALCRL,SCML2,CORO2B,OLFM1,FGFR1,FAM49B,RAB30,PRUNE2,LILRA2,LIFR,LSS,MATN3,KITLG,NOVA2,PPARA,PID1,CCDC40,TCP11L1,ST6GAL1,PREX2,SLC8A1,PHLDB1,ADGRL3,TBCEL" Drug 6272_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,C1QTNF1,SLC4A4,ATP2B2,SCAPER,BAIAP3,HOMER3,CSF1,FAM169A,CTH,HDAC4,RCAN1,EIF4G2,NCALD,DLC1,FYB1,GALC,POLL,IL6ST,KCNF1,KCNQ3,MAP4,ADAM22,NCF2,NPR2,LRP12,POLG,WDR25,RGS4,KLHDC8A,PLCB1,ANKRD12,KIAA0930,PCDHA3,TPM1,WIPF1,XRCC4,SPHK2,REEP1" Drug 6486_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADGRF5,CDC42BPA,PPP4R4,RGS20,LDLRAD4,CA4,GREB1,KIAA0319,RCAN1,ANKMY1,PRELID3A,ALDH1L1,SRCAP,POLL,LIG4,MSI1,NOVA2,PLCD1,LRRN3,PPP5C,RELN,PTPRB,RGS3,SEMA6D,MRAS,HECW1,SAMSN1,THSD1,PLCB1,WSCD1,TRIM2,PCDHGB6,CRTC1,BEX4,CABIN1,TNS1,VIPR2,CLIP2,SLC30A3" Drug 3636_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ALK,AMPD3,APOC1,ARSE,CDK13,GYG2,CACNA1G,DLGAP1,RCBTB2,INTS1,TMCC2,HS3ST2,CDON,DLC1,CSPG5,ALDH1L1,GPER1,PCLO,GRM2,SYNPO,KCNJ5,MX1,NELL2,NF1,NPY,TREM2,CDK18,PILRA,MAPK7,PTCH1,ELOVL2,C1orf54,PKNOX2,PLCB1,SYN2,TRIO,TRO,ZNF154,SLC30A3" Drug 6123_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "RALGAPA1,ASIC1,NDRG2,MTUS1,APAF1,ATP6V0A1,SGCE,CAPN3,CRMP1,CSF1,PHF14,DBT,RUSC2,CDON,TOM1,STX2,PIPOX,GAA,ALDH1L1,USP19,GLYR1,SPACA9,KHK,MAP4,SCAMP5,MID1,CNOT4,PDE4B,RETREG1,PLCD1,PPARA,PPP5C,PTCH1,AMBRA1,JMJD6,SYN2,TPM2,ZFP37,KCNAB1" Drug 3193_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SYN3,AMPD3,BIN1,AMT,KCNAB2,GAS7,DDO,ATP1A3,CACNB4,CAPN3,RUNX1T1,TAOK2,SLIT2,RAB33A,RGS6,VCAN,MBNL2,MTSS1L,ACSL4,GATM,GNAO1,AFDN,ADAM22,MYCN,TREM2,PLTP,PPP1R1A,RASGRF1,CCDC102B,KCNIP1,ASAP3,CNKSR2,ARHGEF40,TSNAXIP1,CDK19,PLCB1,DICER1,TK2,TRPM2" Drug 1500_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,ADGRF5,AMT,APAF1,BCAS1,BACH1,MPDZ,CFLAR,ST3GAL5,MTMR2,BAIAP3,CFAP410,TAOK2,NECTIN3,SH2B1,PDE4DIP,GPRASP1,MFAP3L,EDNRA,SCARA3,ANKFY1,EFCAB2,GRIK5,MBD1,KITLG,MSI1,SETD4,LRRN3,PTN,EMID1,FRMPD1,PPP4R3A,PKNOX2,SPART,ST5,TAL1,TRIM2,NT5M,KCNAB1" Drug 5959_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "C1QTNF1,BIN1,AMT,EPB41L5,ADGRB2,MPDZ,CRLF1,RAB33A,ARHGAP32,DAPK3,MFAP3L,DPH1,PLXNC1,TNK2,PIPOX,ST3GAL6,FGF1,FGFR1,FYB1,MSL3,GRIK5,ICA1,IL12A,KCNJ5,NF1,RETREG1,MAPK7,BEND5,GSTCD,RASA3,SIRT2,KDM4C,ARHGAP26,DDN,ASTN2,TUBB1,NT5M,HPS4,MPPE1" Drug 4641_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,CDC42BPA,PDE8B,ATP2B2,BAIAP3,BAG4,CPS1,CSF1R,ARHGEF4,FAM131B,MFAP3L,SPOCK3,AASS,MRNIP,NRN1,SCARA3,ANKFY1,ZNF44,GFER,LIG4,PPARA,KLHDC8A,TRAPPC13,CSRNP3,ATXN7,SUPT20H,FRMPD1,SLA,MYH15,DDN,TCF4,TIMP4,BHLHB9,RIMBP2,RUNDC3B,AMACR,NT5M,KCNAB1,KAT6A" Drug 5664_DN Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,AMPD2,APC,APOC1,CA4,B4GALT6,TAOK2,HOMER3,ARMC8,RCHY1,ARHGEF10,PDE4DIP,DZIP3,CTH,ZNF804A,FAM49B,PRELID3A,INPP5K,MALT1,POLL,CNTRL,HNMT,IL6R,TM6SF1,ZNF862,SLC11A2,PRODH,ZSCAN32,RIPOR1,CCDC25,FERMT1,LIMCH1,SS18,EXOC7,AP4E1,FAM155A,VAV1,LMF1,ZBTB38" Drug 402_DN rapamycin; Down 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BRAP,APBA2,CDK10,ARNTL,MPDZ,SLIT2,CSNK1E,PDE4DIP,RGS17,SPEG,EZH1,FGFR3,CAMKK2,GNAO1,SLC2A6,C2orf72,KHK,L1CAM,MBD1,ADAM22,PLCD1,SMIM7,NKAIN1,SAFB,SGK1,KBTBD4,ELMO2,ZC3H13,ZBTB43,CLSTN2,SEPT8,PRRC2C,IQCE,TBL1X,TMPO,TRIO,GDPD5,MPPE1,ST7" Drug 5266_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,NME5,LTBP4,FGD2,KCNAB2,CFAP410,USP2,COL9A3,PDE4DIP,MAML1,EDN1,C3orf18,ERCC2,OLFM1,GATM,SRCAP,GNAO1,ADAMTS13,TJAP1,KCNN1,KCNN2,SMAD1,ADAM22,NCF2,NTRK2,PLCB2,RPS6KA2,SEMA6D,SBF1,SLC11A1,SMARCD3,EXOC7,DMXL2,ZEB1,SZT2,PCDHGA10,PIK3R5,FLRT2,NT5M" Drug 4069_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,MARK4,IL33,KRIT1,ARHGEF1,LARGE1,QKI,LY86,AKAP5,SLITRK5,KIAA0753,PLPPR4,PARD6A,PLXNC1,COQ7,MTSS1L,ETV1,ZNF589,FGFR1,ANKFY1,TRAF3IP2,KIFC3,MEF2C,MYT1,NPR2,RETREG1,BEND5,FBXW7,RPS20,CSRNP3,SLC4A3,FAM214B,SLC9A5,ZBTB43,EXOC7,R3HDM1,AMACR,UGT8,AAAS" Drug 4550_UP Methimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,GAS7,SLC4A4,ALDH7A1,ST3GAL5,CACNA2D1,CAMK2B,CBS,SCARB1,NRG2,CPS1,ENTPD4,ZNF589,FLT1,CSPG5,ERAP1,GNG4,GPER1,ITGA7,JAK2,KCNJ5,NF1,NPTX1,P2RY1,PRKAR1B,PRPH,CNNM2,PTPRN2,ASAP3,AMBRA1,FBXO11,SLC11A1,ZHX3,RBM26,ADGRL3,KIAA1107,R3HDM1,TPM2,NT5M" Drug 2144_DN Protoveratrine A [143-57-7]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SYNJ2,CACNA1A,CNTN1,ENTPD4,VCAN,DGKG,SGSM2,RASGRP2,ZNF589,FHL1,FLT1,AFF2,USP19,GLYR1,GPD2,KCNJ5,GIT1,MYT1,P2RY1,CCSER2,SMOX,PILRA,POU6F1,CNNM2,PTPRN2,CCDC25,SH3BP2,EPN2,SLC11A1,DOK5,IZUMO4,UNC5B,PLCB1,PDLIM2,KAT6B,ZNF32,ZBTB38,GDPD5,PHTF2" Drug 7294_UP Imipenem [74431-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "GAS7,CDK13,KIF1A,MYRF,CAMK2B,TAOK2,RAB26,CNTNAP2,LYPD1,SPOCK3,DTNA,REEP2,TPK1,PRELID3A,GAD1,GRIK5,ATXN2L,INPP5B,KHK,KIFC3,MX1,PALM,WDR25,RIPOR1,ZCWPW1,ZNF331,ARHGAP26,SPTAN1,LHPP,THSD1,KIAA1107,SYNE1,CRTC1,CABIN1,TRIO,TRPM2,LMF1,NT5M,MPPE1" Drug 4561_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ALK,AMPD3,APBB2,APC,MYRF,HAPLN1,CSF1,CHRDL1,EDIL3,MRNIP,SPEG,ETV1,CINP,SEPT9,SRCAP,USP19,GPR37,SHISAL1,TJAP1,SCIN,MAPT,MT1M,MYO7A,PALM,PCDH9,PPP5C,ASAP3,ZHX3,UNC5B,DDN,THSD1,ST5,PHLDB1,CRTC1,RPRM,SPHK2,TFIP11,HPS4,SEMA3B" Drug 6334_UP Benzonatate [104-31-4]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BIN1,SEMA4G,KIF1A,SYNJ2,BAIAP3,CACNA2D1,RUNX1T1,SYNGR3,SULT4A1,RAB26,PICK1,CNTN1,ENTPD4,AATK,PARD6A,FAM13A,TRAF3IP2,SRCAP,AHDC1,ADAM28,HNMT,IL6ST,MYH3,LYRM9,PIK3R1,MINDY2,ENOX1,GAL3ST4,SUPT20H,ST6GAL1,EPN2,PKNOX2,ARHGEF40,IFT122,KDM4C,TK2,ZNF74,TFIP11,SEMA3B" Drug 2953_UP Lymecycline [992-21-2]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,ALK,APOC1,PLAA,SULT4A1,AKAP6,ABCG1,CRYM,CNTNAP2,ZNF337,TM9SF4,EXOG,DRP2,CELSR3,TNK2,RASGRP2,ZNF549,ETV1,F5,PTK2B,ST3GAL6,GATM,KCNMB4,PADI2,HNMT,KHK,AFDN,MYO7A,NOVA1,OXTR,PLCD1,MRAS,FAM102A,ASAP3,ST5,EXOC7,PDLIM2,ZNF34,KCNAB1" Drug 5458_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AP2A2,APBB2,PPFIA3,CDC14B,ARHGDIG,ARRB1,SYNJ2,BAIAP3,CBFA2T2,CLGN,QKI,ARHGEF6,ABI3BP,CRY2,SIPA1L1,PDE4DIP,PPP6R2,KIAA0586,VPS13B,ZNF589,FHL1,B4GALNT1,AHDC1,GPER1,INPP5B,JAK2,KIF2A,NTRK2,SMIM7,LRP12,NKAIN1,LIMCH1,MAPKBP1,KDM4C,EXOC7,IQCE,EVI5,GDPD5,SENP7" Drug 2320_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "RALGAPA1,ADORA2A,SPARCL1,ALK,CDC42BPA,CDK13,RASL11B,ADGRB1,CFLAR,MTMR3,GYG2,BAIAP3,CFAP410,CACNA1A,CDO1,TAOK2,NCOR2,VCAN,CYBB,SPOCK2,TMCC2,DTNA,FGFR1,PDLIM5,DISC1,SRCAP,GPR37,KCNJ5,KPNA5,PLCB2,CEP41,PTCH1,SLC9A5,SLC11A1,ZSWIM8,ATP10B,SSTR2,KIAA0930,OSBP2" Drug 4636_UP Chlormezanone [80-77-3]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,ADCY6,ADGRF5,CDK10,SLC4A4,N4BP2L1,KSR1,DLGAP2,STOML1,RAB26,NRG2,VCAN,PPP1R16B,CALCRL,FYB1,GNAL,LILRA2,IL6ST,LIFR,CLDN11,P2RY1,PDE4B,PDE4D,PPARA,PTH1R,ST8SIA1,PEX26,ZNF423,ARHGAP26,ATP10B,NXT2,PHLDB1,ARC,ASTN2,CRTC1,ZKSCAN5,VLDLR,SPHK2,SLC17A7" Drug 4438_DN 2-propylpentanoic acid; Down 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "PPP4R4,ATP1A3,SLC4A4,ADAM23,SCAPER,MTMR3,ARHGAP33,NRXN3,AKAP7,IQCK,ARHGEF4,DAPK3,EIF4G2,EZH1,CGREF1,NEU3,SRCAP,POLL,GRIK5,ATXN2L,SHISAL1,SCIN,KIT,NF1,SLC25A23,WDR25,PTPRE,ZSCAN2,KIRREL1,ATXN7,MRAS,FBXO11,SLA,PPP4R3A,TMCC1,UNC5B,DDN,VIPR2,DPF3" Drug 2820_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "KIAA1324,AK2,AMH,EPB41L5,PRX,PLA2G4C,PDE8B,SCAPER,CA4,CACNA2D2,ASIC3,CNOT8,AKAP7,WHRN,RCHY1,OSBPL3,RIMS2,DCAF4,ARHGAP24,RASSF2,C2CD2L,ZNF589,SEPT9,DHX35,ICA1,KCNQ3,NOVA2,PPP5C,CNNM2,RGS12,HECW1,CLSTN2,CRTC1,CABIN1,TNS1,VIPR2,ZNF154,SMIM8,TIGD6" Drug 7019_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADRA1D,NME5,C1QTNF1,ALCAM,SRPX,AMT,ARHGDIG,SLC4A4,CFLAR,SCAPER,MTMR3,CACNA1G,CFAP410,CBFA2T2,RCHY1,ENTPD4,MFAP3L,EIF4G2,ING4,FGFR1,FAM49B,ELOVL5,INPP5B,MATK,MYCN,NF1,NNAT,PLTP,EMID1,FBXO11,KANSL3,ERC1,MCF2L,SMG6,KIAA0930,PCDHA5,CHST5,ZNF45,PLSCR4" Drug 7184_DN Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,AK2,C5,HOMER3,CDC42BPB,CREM,DCAF8,NR1D2,SEZ6L2,MRNIP,FYN,B4GALNT1,SEPT9,CLASRP,MBD1,MIA2,MITF,PRKAR1B,VPS13C,RAD51D,MSANTD2,RIC8B,C12orf49,FBXW7,SEC14L1,CCDC92,MAPKBP1,ZHX3,ZBTB43,ARHGEF9,PJA1,IQCE,TRIM2,TNS2,TSC2,VAV1,ZNF24,TFIP11,MARCH8" Drug 7241_UP Mesalamine [89-57-6]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,ASIC1,KDM5D,NDRG2,AMH,AMPH,ARRB1,ATP6V0A1,NRP2,SCAPER,GYG2,ARHGEF2,SRSF11,STOML1,HAPLN1,RIMS2,CNNM1,DLC1,KAT8,HPCAL4,KHDRBS3,ZNF44,GALC,POLL,GRM8,HNMT,LIFR,KITLG,MITF,FAM184A,KCNIP1,SYBU,SYN2,CRTC1,SLC44A1,AMACR,UBE3A,FLRT2,VIPR2" Drug 2878_DN Iobenguane sulfate; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,PPFIA3,SEMA4G,BCL7A,SCAPER,ABI3BP,PHF14,LYPD1,DNM1,TOM1,ZNF589,FHL1,DISC1,TJAP1,MAP4,TM6SF1,GIT1,NEK1,NPR2,NTRK2,PDE4A,NLE1,PLCD1,PPP5C,MAPK7,PRPH,CNNM2,RIPOR1,ZSCAN2,CEP97,NEK11,SH3BP2,ABLIM3,CXXC4,RBM34,ZNF34,UBE3A,DNALI1,RNF170" Drug 5534_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "C1QTNF3,OGT,APC,MARK4,NUMB,LRRFIP1,NCOR1,PDE4DIP,C2CD2L,CDON,MAMLD1,ING4,EPB41L2,DLC1,FHL1,CINP,MALT1,GRB10,DIDO1,RNFT2,INPP5B,KHK,LMO2,MPP2,PRPH,RGS3,GSTCD,ZNF821,PPP4R3A,INTS9,LHPP,SATB2,TRIM2,SLC44A1,PIK3R5,PLPPR2,VGF,TFIP11,EMSY" Drug 668_UP monastrol; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BIN1,SEMA4G,EIF4G3,STX16,ATP2B2,CFLAR,BMP7,CACNA1I,HAP1,CCNT1,CNOT8,TMEM184B,CNTN1,CRYM,DMD,FCGRT,USP19,RUNDC3A,CACFD1,MAN1B1,ICA1,GPSM2,FA2H,PPP2R2B,MAPK7,RGS3,GSTCD,MAPK12,ZNF821,SGK1,ASAP3,SLC12A4,PHLDB1,ARHGEF9,EXOC7,TCF4,CHST5,ZNF189,SLC17A7" Drug 603_DN nifedipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ACTN1,ADD2,BRAP,APBB2,ARNTL,MTMR2,CCK,ENTPD4,SH2B1,BRINP1,GIT2,DBT,DPP6,ACOT8,RCAN1,E2F5,ING4,TMEM8B,GPD2,LILRA2,NXPH3,AGBL5,KIFC3,NEK1,NELL2,NLE1,MINDY2,PPP2R2B,LRRN3,RELN,RBBP6,SAFB,ZNF821,SLC11A1,RCOR3,TMCC1,NMNAT2,BHLHB9,TRIO" Drug 1502_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,ADD1,DOC2A,EPB41L5,CFLAR,CFAP410,ARHGEF1,PLEKHB1,HOMER3,CRY2,ABCG1,CSF1R,MAML1,FBXL5,SLC12A6,RCAN1,ZNF589,SEMA4D,FAM49B,TXNL4A,FERMT2,HNMT,ITPKB,MIA2,NF1,NPR2,SLC25A23,MAPK7,TMEM104,RIPOR1,FERMT1,SLC6A8,BTBD7,LHPP,PHLDB1,PDLIM2,PARD3,VGF,REEP1" Drug 2555_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD2,AP2A2,AMH,PKP4,ATP2A2,ATP6V0A1,RHBDL1,CLGN,SULT4A1,CSNK1E,CNTNAP2,DZIP3,RIMS2,TMCC2,ING4,C3orf18,PTK2B,ZNF589,PCDH17,GPD2,SYNPO,L1CAM,NRCAM,PDE4A,PLCD1,SLC25A23,CNTLN,ZMAT4,RGS12,ZNF821,SLC9A5,SLC11A1,SPTB,ATP10B,ARHGEF9,CUX2,PCDHGB6,PCDHGA10,TRPS1" Drug 4011_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD2,MTMR3,BAIAP3,MTMR7,DLGAP1,PLEKHB1,NCOR2,CSF1R,LRIG1,RIMS2,EXOG,DTNB,CELSR3,RGS17,ETV1,OGA,FYB1,GABRA3,SIGLEC8,RUNDC3A,GNAL,STON1,HLF,ICA1,MAN2A2,ADAM11,NF1,NTRK3,P2RX7,RETREG1,BEND5,RTN1,SCN2B,MRAS,FUZ,ZNF334,MCF2L,R3HDM1,PHTF2" Drug 4537_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,C1QTNF1,APC,MARK4,KIF1A,CBFA2T2,PLEKHB1,ABCG1,ARHGEF4,PLPPR4,TOM1,FEM1B,TENM1,ETV1,MSL3,HAS2,SCIN,INPP5B,NDP,CNOT4,KCTD15,SAMD9,FAM184A,ZNF821,ZFP30,ST6GAL1,DZIP1,CCDC88A,SLC14A1,THSD1,PLCB1,ASTN2,EXOC7,DOCK9,TNS1,ZKSCAN5,TRIM9,NDRG4,MAP3K12" Drug 2579_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AMH,PKP4,PRX,LHX2,EPS15L1,HOMER3,SLITRK5,DAPK3,HIPK3,ERBB2,PTK2B,FGFR1,NBEA,CAMKK2,KHDRBS3,ERAP1,GCNT2,ZNF276,GNG4,GPD2,LILRA2,GSN,RASSF8,TJAP1,LSS,TAGLN3,MX1,PURG,EPB41L4B,POU6F1,CNNM2,PTPRB,RXRA,SH3BGR,ATP10B,PHLDB1,EXOC7,CHST5,PARP11" Drug 2449_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG3,ADRA1D,AMH,APOC1,CASK,NCOA1,SCAPER,ARHGAP33,PLAA,CLTB,IQCK,DAPK3,FHL1,CINP,GATM,SRCAP,SPACA9,NCKAP1L,MEF2C,CNOT4,SLC11A2,SLC25A23,ZCWPW1,ZNF493,EMID1,MRAS,EPN2,MAPKBP1,DOP1A,SPTAN1,EXOC7,PDLIM2,ADGRL3,SYNE1,OBSL1,CHST8,LMF1,MAP3K12,TIGD6" Drug 315_UP "aspirin, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "KDM5D,ALK,BIN1,CDC14B,DNAH17,CACNA1A,ARHGAP33,ING4,STX2,ERCC2,CDKL3,ZNF589,TRAF3IP2,CYP46A1,MCHR1,GRM8,SOX21,NCKAP1L,KCNJ5,MID1,NPTX1,LRRN3,WDR25,RFX2,FRMPD1,FNDC3A,ST6GAL1,SLC8A1,ARHGEF40,NMNAT2,UNC5B,SYN1,OBSL1,PCDHA5,CDH22,TNS1,VIPR2,HRASLS,AP3B2" Drug 284_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,NDRG2,KIAA1324,CDC42BPA,AQP6,SEMA4G,PRX,MYRF,LHX2,AATK,VCAN,CNTNAP2,APPL1,ARHGAP24,DAPK3,DBT,TUBD1,CGREF1,MALT1,KCNMB4,GNAO1,IGF1,KCNJ5,LAMA2,SETD4,RETREG2,RNH1,PREX2,KBTBD4,CDK5RAP2,KDM4B,NMNAT2,KLHL7,THRA,TNS1,WNT7A,TFIP11,KCNAB1,JMJD1C" Drug 4219_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "N4BP2L1,AZGP1,KSR1,BMPR1B,LDLRAD4,CAMK2B,SLC16A4,ARHGEF2,DLGAP1,CBARP,PLEKHB1,CLTB,FAM149A,COL9A3,CRYBB1,CSF1,DMD,EDN3,EPHB1,ZMYND10,RUNDC3A,GLI2,GNAL,IL6R,AFDN,MSR1,NF1,PCSK5,SEPT4,RASGRF1,FRMPD1,SLA,CXXC4,CDK19,PHF24,TEK,TLR4,R3HDM1,KCNK12" Drug 6154_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,AMPD3,APC,RAB33A,AKAP7,IQCK,CRMP1,CRY2,DAPK1,DAPK3,DTNA,FCF1,CDKL3,PIPOX,GAA,SEPT9,ZNF276,GLYR1,GNG4,GPD2,DIDO1,GRIK5,MAP4,MID1,ZNF862,NPR2,CCSER2,RETREG1,PTN,MAP6D1,MRAS,ANKRD6,FAM214B,JMJD6,AP4E1,PARD3,TNS1,SMUG1,KCNAB1" Drug 2921_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,AMPD3,BIN1,CDC42BPA,RASL11B,ATP2B2,LDLRAD4,CBFA2T2,SIPA1L1,RIMS2,KLHL3,EPB41,DLC1,NBEA,PRELID3A,GLYR1,SLC2A6,NXPH3,ATXN2L,KCNN1,MGAT3,MPP2,ZNF862,CNOT4,NPR2,NRCAM,P2RY1,DUSP26,NLE1,PLCD1,PPP2R2B,MORC4,FERMT1,SLC11A1,CRTC1,CHST8,TRIO,FAM155A,LMF1" Drug 3675_UP Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AP2A2,NME5,OGT,N4BP2L1,CACNA1I,USP2,RGN,MYRIP,RIMS2,SEC14L5,RIPOR2,EDN1,SEMA4D,GNAL,LPAR4,ITGA7,ADAM11,TAGLN3,CDK18,PDE4B,ZSCAN32,PTPRO,NKAIN1,RFX2,SH3BP2,SLC6A11,ARHGEF40,CXXC4,SNCA,UNC5B,LMO3,ATP10B,SYN2,ASTN2,EXOC7,PIK3R5,LAT2,ZNF154,SENP7" Drug 4337_UP Proglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,ASIC1,ALK,PKP4,APAF1,RASL11B,KIF1A,BMPR1B,CACNA1I,KALRN,HAP1,CAMK2B,NCOR2,CNTNAP2,SPOCK2,STX2,OLFM1,FGFR1,FERMT2,ITPKA,MAP4,NOVA2,NPTX2,NRCAM,NTRK2,RETREG1,C19orf57,ACSS3,RASGRF1,RGS4,MRAS,ZSWIM8,LMO3,EXOC7,DICER1,CHST5,CA14,UCHL1,LAT2" Drug 2807_DN Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,AP2A2,MTMR2,KYAT1,COL4A5,CRY2,CSNK1E,PDE4DIP,HIPK3,ZNF589,FECH,BAIAP2,IQCG,SEMA4D,CINP,SYT17,RAB30,PRRC2B,MIA2,KITLG,NEK1,SLC25A23,LRP12,ZCWPW1,GTDC1,RNASEL,SGK1,CDK5RAP2,TMCC1,CLSTN2,MCF2L,EXOC7,MGRN1,TRIO,PLPPR2,ZNF23,HPS4,EPM2A,GAN" Drug 5499_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SEMA6A,SEMA7A,APLP1,MARK4,SLC4A4,ALDH7A1,N4BP2L1,CCNT1,CACNA2D2,PLEKHB1,NRG2,DTNA,FAM13A,RASGRP2,SPEG,BAIAP2,IQCG,PDLIM5,GATM,SRCAP,RUNDC3A,IPO5,MSR1,LRP12,PPP2R2B,MAPK7,MRAS,ABLIM3,ELMO2,SNCA,ZHX3,DDN,CLSTN2,SYN2,PCDHGA10,WBP2,TRIO,AMACR,ADAMTS9" Drug 1509_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "GAS7,SEMA4G,ATP2B2,SLC2A11,NRP2,CFLAR,SCAPER,QKI,AKAP6,CSF1,ARHGAP24,HDAC4,CDON,VPS13B,SPEG,FGFR1,ADAMTS13,GRM8,GSTM5,GUCY1A1,ELOVL5,KCNH2,KCNN1,KIFC3,MBP,MMP17,NNAT,PALM,CNTLN,PTN,RFX2,RFX3,FAM214B,PKNOX2,SNAP25,ERC1,PLCB1,SYP,HIF3A" Drug 254_UP SC-58125; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,ADORA1,AMPD3,BIN1,CDK10,ARNTL,CHRD,ATP2B2,AZGP1,CBFA2T2,HOMER3,PCYT1B,NCOR2,ECM2,ING4,ENO2,SPEG,FGF1,FOLR2,ADAM28,TXNL4A,GRM8,FAM107A,NCKAP1L,KCNJ5,PCBP3,RIPOR1,KHDRBS2,GAL3ST4,RGS12,FAM192A,RASA3,FRMPD1,FERMT1,ZHX3,SST,OBSL1,TNS1,WIPF1" Drug 3361_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADORA2A,ADRA1D,MARK4,BMP7,FOXN3,VAX2,PPP6R2,DPH1,FEM1B,IRAK4,STX2,CINP,INPP5K,GCNT2,SRCAP,BTN2A1,INPP5B,LSS,MPP2,NTRK2,PLCD1,SLC25A23,PPP5C,PRKAR1B,PTN,ZSCAN32,RBM34,SPTAN1,SPART,PLCB1,ANKRD12,SIK3,TPM1,ZKSCAN5,VGF,VLDLR,ZNF45,EPM2A,MARCH8" Drug 1915_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HG-U133A" Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,ADD2,EP400,KCNAB2,RASL11B,RGS11,P2RX6,AKAP7,CRY2,ARHGAP32,ARHGAP24,DCAF8,SPOCK2,GIT2,B3GAT3,RUSC2,DTNA,EDN1,SRPK3,FER,SMC2,PDLIM5,HTATSF1,PRRC2B,PADI2,IL12A,KIF2A,IPO5,PIK3R1,MAPK10,TCP11L1,ZNF331,SMARCD3,LHPP,TTBK2,NSD1,TSC2,MPPE1,AAAS" Drug 1648_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BRAP,LTBP4,APOC1,CDC14B,ARNTL,ARRB2,MPDZ,BMP7,GYG2,KYAT1,CRY2,CSNK1E,DBN1,DBT,SGSM2,PCOLCE2,VPS26C,BAIAP2,SPIN1,RNFT2,ITPKB,KCNH2,MAP4,MPP2,NF1,APTX,SH3BGR,PEX26,EPN2,BTBD7,SMARCD3,TSPYL2,ELOVL4,JMJD6,KIAA0930,BEX4,PARD3,LMF1,HPS4" Drug 1205_DN "ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,C1QTNF1,BIN1,OGT,APBB2,MARCH3,SYNJ1,KYAT1,CDH2,LHX2,HOMER3,AATK,PPP6R2,RUSC2,RGS17,SPEG,FGF1,ANKFY1,AHDC1,GLYR1,CNTRL,MUM1,DHX35,IL6R,MIA2,SCAMP5,MPP2,NF1,POLG,PPP3CC,PRPH,ZC3H14,MAP6D1,SH3GL3,ASAP3,LIMCH1,ZBTB43,TCF4,TK2" Drug 1808_UP Acetazolamide [59-66-5]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MPDZ,ARHGEF7,C5,CA12,CBFA2T2,CLTB,AKAP7,CREM,NCOR1,DZIP3,DCAF8,MATR3,ETV1,IQCG,GPR37,CNTRL,ACOT7,HNMT,JAK2,MBNL1,PIK3R1,ZFYVE21,REV3L,HSPA4L,SPTAN1,CAMTA2,SS18,ARHGEF9,TNS2,DICER1,TIMP4,BEX4,R3HDM1,UBE3A,BCL2L13,VIPR2,XRCC4,TFIP11,EVI5" Drug 3140_DN Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD1,BIN1,ANK2,MARK4,CACNA1A,CAMK2G,CCNT1,CNTN1,ENTPD4,CSF1,CSNK1E,ZNF337,SPOCK2,DBT,VPS13B,COQ7,NCALD,FECH,SEPT9,GLYR1,LAMA2,GIT1,NINJ2,PDE4D,STRN3,MAPK7,CNNM2,MARCH1,BEND5,ZFHX4,ARFGAP1,TMCC1,KDM4B,SPTAN1,ARHGEF9,CABIN1,PLPPR2,XRCC4,ACTR3B" Drug 2731_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADRA1D,MTUS1,APBB2,FAM131A,KIF1A,TAOK2,TMEM184B,AKAP7,NRG2,CREM,SUSD5,VCAN,PDE4DIP,USP6NL,MFAP3L,C3orf18,MTSS1L,PIPOX,F5,FHL1,AGAP2,PDLIM5,SRCAP,GPR75,GRM8,JAK2,NNAT,POU6F1,RNASEL,ANKRD6,SLC11A1,MYH15,LHPP,STX1A,SYN2,ADGRL3,ICAM5,MAP3K12,GDPD5" Drug 5428_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD2,FZD9,ADRA1D,PLA2G4C,MARK4,SLC4A4,ST3GAL5,BAIAP3,CAMK2B,CAST,VAX2,NRG2,NCOR2,VCAN,HIPK3,EFCAB2,GAD1,GSN,GSTM5,ATXN2L,KCNQ3,MSR1,PGAM2,PURG,PPP2R2B,PTPRH,PTPRO,ZFHX4,SATB1,ZNF821,ZHX3,IZUMO4,HECW1,ZNF423,SPTAN1,RBM26,ARC,DOCK9,ITM2C" Drug 2564_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "DOC2A,TRMT9B,APAF1,CDC14B,MTMR3,LDLRAD4,SPAG9,TAOK2,FAM149A,ZNF337,GSDME,FCF1,CELSR3,ELN,PIPOX,DLC1,KHDRBS3,MSL3,MAP4,MEF2C,SCAMP5,N6AMT1,OCRL,CCSER2,KCTD15,NLE1,PTCH1,GALNT10,FNDC3A,CNKSR2,NUBPL,LIMS2,BTBD7,SS18,CDK20,UBTF,LMF1,XRCC4,REEP1" Drug 6325_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "LTBP4,SEMA4G,PPP4R4,MARCH3,ATP1A3,BMP7,B4GALT6,NRXN3,ARMC8,WHRN,NCOR2,PDE4DIP,CNTNAP2,PHF14,COQ7,KAT8,DCTN2,OGA,GRIK5,INPP5B,KCNF1,KCNJ5,MIA2,MMP16,MYH3,NF1,NPTX1,RETREG1,DZIP1,PREX2,ELMO2,IFT122,DDN,CEP68,ARHGEF9,FBXW11,TRIO,XRCC4,ZNF45" Drug 3609_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "GAS7,MARK4,BMPR1B,GYG2,CAMK2B,ABI3BP,CPS1,CSF1,GREB1,MAML1,DBT,ELMO1,PARD6A,HS3ST2,DTNB,EDN1,CALCRL,NSG1,GFER,GPER1,INPP5B,KCNN1,KHK,MAN2A2,TAGLN3,ZNF862,PCBP3,OGG1,MAPK7,TMEM231,CRTAC1,SALL1,SLA,TSNAXIP1,WSCD1,OBSL1,PDIA2,VSNL1,SPHK2" Drug 3780_DN Proglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AMPD3,ZSCAN18,BMP7,CFAP410,CACNA2D2,ABCG2,LY86,AKAP5,HAPLN1,VCAN,CNTNAP2,DCAF4,DTNA,ANKFY1,PDLIM5,OGA,ICA1,NELL2,NF1,PALM,PIK3R1,KCTD15,RGS4,DZIP1,OGDHL,RBM34,UNC5B,THSD1,SYN2,FBXW11,ZEB1,CRTC1,TK2,CABIN1,TNS1,ZKSCAN5,LMF1,DPF3,SENP7" Drug 6674_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ALK,CDC42BPA,APAF1,APC,GAS7,ADAM23,CFLAR,ST3GAL5,LHX2,RAB26,CREM,PDE4DIP,SPOCK3,TENM1,ANKFY1,LPAR4,GPER1,SPACA9,HLF,FAM69A,LIFR,MEF2C,CNNM2,SNRK,CNTLN,PTPRE,GSTCD,ZFP30,ASAP3,DZIP1,PEX26,FAM214B,TMCC1,LHPP,IQCE,KIAA0930,VGF,TFIP11,PHTF2" Drug 6658_UP Luteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,AK2,PKP4,KCNAB2,EPB41L5,ATP2B2,ADGRB2,CFLAR,CFAP410,HAP1,SLC16A4,SCARB1,FHL5,ENTPD4,CRY2,SPOCK2,DTNA,IGSF6,CDKL3,ETV1,FGF1,ADAM28,CSDC2,CACFD1,NCKAP1L,KCNB1,KCND2,KCNJ5,NECAB2,CEP41,FBXW7,ZFP2,SLA,ZNF334,ZBTB43,ATP10B,PHLDB1,UCHL1,KCNAB1" Drug 6641_UP Khellin [82-02-0]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADCY6,LTBP4,SEMA7A,ADAM15,CAST,KRIT1,WHRN,ENTPD4,DBN1,CHRDL1,MBNL2,REEP2,FCGRT,ZNF589,FLT1,ZNF276,ATXN2L,IL12A,TM6SF1,MMP16,OGG1,PALM,PDE4B,PFKFB4,PPP5C,TMEM231,RAD51D,RNASE1,SEMA6D,SLC11A1,FAIM2,COBL,MCF2L,GPR161,TMPO,R3HDM1,UBE3A,KCNK12,ZNF24" Drug 6357_UP Condelphine [7633-69-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADCY6,ADGRF5,ALK,APAF1,APBB2,SEMA4G,DNAH17,IL33,CACNA2D2,CNOT8,NCOR2,AATK,CDON,EDIL3,FAM13A,EGFR,IRAK4,EZH1,ERAP1,SRCAP,PCDH17,INPP5B,KIT,LIG4,NELL2,NF1,NFYA,PPARA,LRRN3,ACSS3,GAL3ST4,NEK11,SMPD3,ZFP30,KDM4C,ARHGAP26,FRYL,RUNDC3B,SMIM8" Drug 4628_UP Crotamiton [483-63-6]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADCY6,AP2A2,ADGRF5,BIN1,GAS7,PPP4R4,N4BP2L1,NRP2,KSR1,KALRN,DLGAP1,VAX2,NRG2,DTNA,ZNF549,FYB1,TMEM8B,SIGLEC8,GNAL,GSTM5,TAGLN3,LYRM9,NF1,RETREG1,NLE1,MTRF1L,POU6F1,RASGRF1,KCTD17,HKDC1,SLC4A3,KANSL3,ZHX3,ZNF423,ARHGAP26,SYN2,PCDHA5,TNS1,VIPR2" Drug 2354_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ALK,BIN1,AMT,MARK4,CFLAR,BMP7,GYG2,LDLRAD4,CBFA2T2,B4GALT6,RAB33A,STOML1,SULT4A1,HOMER3,SIPA1L1,ZFYVE16,E2F5,TNK2,NCALD,FGFR1,SIGLEC8,MSL3,LPAR4,KCNQ3,MAPT,MMP16,MPP2,GIT1,MYCN,P2RX7,PLTP,TCP11L1,SEC14L1,SH3BP2,SNCA,KDM4B,TK2,SLC17A7,KCNAB1" Drug 6550_UP PHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BRAP,ALCAM,AMPD3,BIN1,CAMK2B,ARHGEF1,FOXN3,AKAP7,ABCG1,LRIG1,MFAP3L,RUSC2,DTNB,TOM1,APH1A,C3orf18,MTSS1L,NCALD,INPP5K,GNG4,GPER1,GRB10,DHX35,ICA1,MBOAT7,FBXW7,KCNIP1,FERMT1,EPN2,KDM4B,THSD1,TTBK2,DMXL2,BEX4,HIRA,LMF1,LAT2,FAM13C,KAT6A" Drug 3074_DN Tyloxapol [25301-02-4]; Down 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AP2A2,ATP6V0A1,LDLRAD4,SLC16A4,SOCS6,EPS15L1,BAG4,VCAN,SPATA2,DTNA,FAM13A,PLXNC1,EIF1,RASGRP2,ERCC2,PRKAG2,ERAP1,GLYR1,GPD2,LILRA2,SLC11A2,ZNF426,PTN,ZNF493,RXRA,SLC2A5,SLC6A8,CDK19,RBM26,ADGRL3,TBL1X,DMXL2,TPM2,TRPS1,HIRA,XRCC4,ZBTB14,SPHK2,NT5M" Drug 309_DN sulindac sulfone; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NME5,BEGAIN,OGT,ANK2,PKP4,APBB2,ARHGDIG,SYNJ2,CAPN3,ARHGEF2,CPS1,SPATA2,TMCC2,ERBB4,EXTL2,DLC1,FGFR1,PRKAG2,SUCO,SMC2,DISC1,RUNDC3A,HSF2,ADAM22,NF1,NNAT,PLEC,PRKAB2,MAPK3,PRPH,MTMR10,SUSD4,SUPT20H,ZKSCAN3,SNCA,TRIM2,TNS1,TFIP11,EPM2A" Drug 6244_DN Hexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "APBB2,APC,MADD,EIF4G3,CFLAR,SYNJ2,SLC4A8,PDE4DIP,DNM1,DTNA,IRAK4,CDKL3,F8,FGFR1,FHL1,TRMO,MSL3,KCNMB4,DIDO1,KHK,MAP4,MAPT,NEK1,PRPH,RIPOR1,TMEM231,FAM184A,ZDHHC14,ROBO1,ZKSCAN3,UNC5B,ZBTB43,TROVE2,CAMTA2,ANKRD28,ANKRD12,OBSL1,PARD3,NDRG4" Drug 5309_DN Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABR,NCOA1,SYNJ2,ARHGEF7,MTMR2,CBFA2T2,SCARB1,CLOCK,CSNK1E,INTS1,DBN1,PLEKHA1,FGFR1,ANKFY1,FAM49B,CELF1,GAA,PRRC2B,MEIS1,MITF,MYO9A,OGG1,MINDY2,PRKAR1B,TMEM104,PTK2,CLIP1,NCBP3,ZNF331,MAPKBP1,TROVE2,SEPT8,PLCB1,TCF12,TRIO,FTSJ1,TFIP11,MPPE1,SMIM8" Drug 6702_DN Niacin [59-67-6]; Down 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SLC4A4,CBFA2T2,SYNGR3,PDE4DIP,CNTNAP2,SGSM2,DPH1,CNNM1,EGFR,COQ7,DENND4A,B4GALNT1,COPS8,MSL3,POLL,CNTRL,BACH2,IL6ST,FAM69A,MMP16,PDE4D,RETREG1,PPARA,PPP3CC,PTCH1,PTN,PTPRE,C1orf54,MRPS18A,SCN8A,ASAP3,FBXO11,SLC4A3,UNC5B,SPTAN1,THSD1,THRA,ZNF45,KCNAB1" Drug 5996_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SEMA7A,APBB2,GAS7,BACH1,RUNX1T1,CLGN,RAB33A,NRXN3,QKI,NECTIN3,SLITRK5,RUSC2,DMPK,DUSP9,C3orf18,STX2,FGFR1,GPD1,GRM2,HAS2,KCNN2,NNAT,NPTX1,NECAB2,ELOVL2,KLHDC8A,SEMA6D,RASA3,ASAP3,CNKSR2,PKNOX2,SMARCD3,DOP1A,ARHGAP26,THSD1,WSCD1,ZEB1,OBSL1,R3HDM1" Drug 4462_UP "ICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD2,ADRA1D,PKP4,SLC2A11,KIF1A,NRP2,BMP7,CHN2,HAPLN1,PDE4DIP,TENM1,APC2,FAM49B,ERGIC3,OGA,AP4S1,FAM107A,ATXN2L,IL6ST,KCNF1,SAMD14,NPY,NPTX1,NPTX2,PALM,ENPP2,PFKFB2,MTRF1L,PPP2R2B,PTCH1,PTN,RNASE1,SEMA6D,SCN8A,CNKSR2,LIMS2,CXXC4,SYN2,TACR1" Drug 4383_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "KIAA1324,CDC14B,SEMA4G,SYNJ1,CACNA1I,HAP1,CAMK2B,ARHGAP33,AATK,CSF1,CSF1R,ERCC2,PTK2B,GRIK5,ICA1,KCNH2,KHK,KIFC3,TM6SF1,MID1,NTRK2,PPARA,MAPK10,ZSCAN32,RIPOR1,ZDHHC14,RGS12,RASA3,SLC9A5,KIF13A,UNC5B,JMJD6,SZT2,CRTC1,SLC44A1,TRPM2,VGF,VIPR2,KCNAB1" Drug 456_DN (-)-quinpirole hydrochloride; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "BIN1,ARNTL,BCL7A,SCARB1,LRRFIP1,SULT4A1,ARHGAP32,DYNC1I1,ECM2,IRAK4,ERBB2,ETV1,VPS26C,EZH1,FOLR2,NSG1,GDF9,GNG4,GUCY1A1,ATXN2L,VSIG4,L1CAM,STMN1,MMP17,ADAM22,OPRL1,CDK18,NLE1,SMOX,MBOAT7,RGS4,PNMA8A,RPS6KA2,FNDC3A,PEX26,SLC8A1,CDK5RAP2,PARD3,TRPM2" Drug 6935_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASPHD1,ABHD6,AP2A2,SEMA6A,BIN1,MARK4,CAMK2A,HIP1R,LHX2,FAM149A,PDE4DIP,FAM169A,KIAA0586,FHL1,OGA,GAD1,GFER,GNAL,LPAR4,GRB10,DHX35,MAPT,MPP2,PPP2R2B,RGS3,EMID1,SEC14L1,LIMS2,FAM214B,ELMO2,KDM4B,UNC5B,SPTAN1,IQSEC2,CLSTN2,ANKRD12,TMEM121,GDPD5,TIGD6" Drug 5844_UP Folic acid [59-30-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,MTUS1,AMT,ARNTL,SLC4A4,CFLAR,HAP1,CRLF1,ASIC3,CNOT8,AKAP7,PDE4DIP,DCAF8,GIT2,KIAA0753,EGFR,RRAGB,SCML2,FGFR1,OGA,FYN,ERAP1,BACH2,MATN3,MMP16,LRP12,ZNF821,SLC14A1,IFT122,TMCC1,TSNAXIP1,KDM4C,ZBTB43,PLCB1,ASTN2,TRPM2,FAM155A,UBTF,AAAS" Drug 6480_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADORA2A,CDK10,SLC4A4,CFLAR,MTMR2,BAIAP3,CA12,SYNGR3,ARHGAP33,ABI3BP,LRIG1,PDE4DIP,ZNF804A,PRELID3A,INPP5K,GNG4,TDRKH,RASSF8,HNMT,MAPT,TM6SF1,LYRM9,NELL2,NFYA,NPTX1,SETD4,PTCH1,RGS3,FBXW7,ZNF821,NLGN1,SLC6A8,CXXC4,TROVE2,TACC1,CABIN1,PCBP4,EPM2A,SMIM8" Drug 3678_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AMPD3,CDC42BPA,APAF1,SLC4A4,BAIAP3,CA12,LARGE1,TAOK2,PICK1,CNTFR,IQCK,ABCG1,PPP6R2,DAPK3,CDON,ING4,FGF1,SYT17,SRCAP,GNG4,ELOVL5,INPP5B,KCNB1,KCNJ5,MYO7A,PRKAR1B,PTPRB,TCP11L1,ASAP3,DZIP1,KIF13A,RBM34,SPTAN1,CEP68,COBL,PARD3,AMACR,RPRM,EVI5" Drug 6209_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "CDC14B,BMP7,ARHGEF7,C5,CCNT1,SCARB1,SYNGR3,DCAF8,ZNF337,MRNIP,FHL1,DISC1,MALT1,GPD2,ICA1,MEIS2,MITF,PDE4A,PDPK1,PLEC,PMP22,POLG,PRKAR1B,RIPOR1,NKAIN1,SUSD4,MSANTD2,SAFB,SEC14L1,SGK1,AMBRA1,FNDC3A,INTS9,KDM4B,TROVE2,POGZ,LMF1,TFIP11,PCBP4" Drug 3073_UP Flucytosine [2022-85-7]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SYN3,CDC42BPA,BCAS1,ARRB1,DNAH17,MYOM1,CFAP410,CACNB4,TAOK2,CNTN1,CREM,ABCG1,RIPOR2,DGKB,EPB41,ETV1,PDLIM5,CGREF1,ALDH1L1,RUNDC3A,KCNQ3,MAP4,AFDN,TAGLN3,MYT1,NRCAM,PCDH9,PLEC,PPP2R2B,PPP5C,GAL3ST4,ZFHX4,ST6GAL1,CXXC4,DOK5,SZT2,ICAM5,CLIP2,SPHK2" Drug 61_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,NDRG3,GAS7,PPFIA3,CHRD,CACNA1A,CAMK2B,CHN1,NCOR2,DNAJB6,EPHB1,OLFM1,FGF12,BAIAP2,SEC23B,ADAMTS13,NCKAP1L,SYNPO,KCNB1,KCNN1,KIF5A,L1CAM,MBNL1,MMP17,MYT1,NELL2,CDK18,PDE1C,PLCD1,AMBRA1,PEX26,PKNOX2,SLC11A1,KBTBD4,TBL1X,PARD3,TRIO,PLPPR2,VIPR2" Drug 2663_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,LGR5,AZGP1,NRP2,BMP7,HAP1,CRMP1,OSBPL3,PDE4DIP,DCAF4,USP6NL,SPOCK2,C2CD2L,HIPK3,SRPK3,VPS13B,FHL1,AGAP2,PDLIM5,NSG1,ERAP1,GNAO1,MEF2C,PDE4D,PFKFB2,PGAM2,CCSER2,SLC25A23,PRKAR1B,ACSM5,CXXC4,TMCC1,SOX15,SLC19A3,CRTC1,THRA,TRPS1,SLC17A7,PHTF2" Drug 5634_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,NME5,PDE8B,MTMR2,STOML1,PDE4DIP,DOCK4,RRAGB,F8,FGFR1,IQCG,DISC1,ALDH1L1,SRCAP,GLYR1,CACFD1,RASSF8,KITLG,NEK1,PPP5C,MAPK7,RPS6KA2,SBF1,SH3BP2,FNDC3A,FAM214B,BTBD7,ZKSCAN3,COA1,SPART,TROVE2,PLCB1,KIAA0930,FAM155A,ZFP37,ZNF711,ZNF32,EMSY,URM1" Drug 6074_DN Anabasine [494-52-0]; Down 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ABHD6,AP2A2,MTMR3,CA12,CNTN1,CRY2,CSF1R,RIMS2,TBC1D5,DAPK3,TMCC2,DTNA,DUSP9,HIPK3,FEM1B,MRNIP,C3orf18,ENO2,ZNF589,GNG4,GRB10,ITPKB,TM6SF1,PRKAR1B,PRPH,NKAIN1,FAM184A,ZNF821,PEX26,SNCA,ST5,PLCB1,SYN2,MCF2L,PCDHA6,ZNF34,SLC44A1,TIAM1,PLPPR2" Drug 4606_UP Metyrapone [54-36-4]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SYN3,SEMA6A,CDC42BPA,APOC1,KSR1,BMPR1B,HAP1,CAMK2B,NRG2,ARHGEF10,PDE4DIP,SPOCK3,ZNF549,EZH1,AGAP2,DOT1L,FYB1,SYT17,NEU3,HPGDS,HNMT,MSR1,NF1,PTPRN2,C1orf54,ZCWPW1,SH3BP2,CNKSR2,ANKRD6,KANSL3,DDN,SPART,SAMSN1,SYP,ADGRL3,OBSL1,VIPR2,SENP7,JPH3" Drug 6290_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,ADGRF5,APAF1,DDO,PDE8B,LDLRAD4,RAB33A,SULT4A1,ABCG1,CSF1,DTNA,PLXNC1,IRAK4,COQ7,EPHB1,TRMO,USP19,ZNF276,STON1,HSF2,IL6ST,GIT1,ZNF862,CLDN11,FBXW7,TCP11L1,KIF13A,RBM34,SS18,PHLDB1,ARHGEF9,KIAA1107,PCDHA6,ZFPM2,TIAM1,TLR4,LMF1,LAT2,AAAS" Drug 5949_DN AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADRA1B,PKP4,CDK10,ATP2A2,NRP2,PROM1,ST3GAL5,SCAPER,NFS1,ARHGEF1,SOCS6,NCOR2,CNTNAP2,RUSC2,ERCC2,NRN1,GCNT2,GPER1,HSF2,SCIN,INPP5B,KCNN1,MAPT,MEF2C,AFF1,MMP17,P2RY13,CDK18,PPP5C,WDR25,PTN,IFT122,KDM4B,POGZ,TNS2,FRYL,TIMP4,KCNAB1,AAAS" Drug 7171_UP Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "APBB2,CFLAR,AP4M1,ARHGEF10,PDE4DIP,HDAC4,DAPK3,MFAP3L,LYPD1,DTNA,MTSS1L,ERCC2,ACSL4,AGAP2,SEMA4D,PRELID3A,ZNF44,SIGLEC8,MALT1,ATXN2L,NFYA,PCDH9,STRN3,POLG,PRKAR1B,PRPH,WDR25,ZFP30,PPP4R3A,SPTAN1,IQSEC2,ZC4H2,JMJD6,PLCB1,ARC,TPM1,CDK20,AMACR,ZNF189" Drug 2083_DN Isoniazid [54-85-3]; Down 200; 29.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,ABHD6,ADCY6,C1QTNF1,BIN1,AMT,ARRB2,CFLAR,CNOT8,AKAP7,WHRN,CREM,CSNK1E,PDE4DIP,CTH,ARHGEF4,PARD6A,DYNC1I1,ERBB2,SPEG,F8,BAIAP2,TRMO,ZNF276,GPER1,DIDO1,RNFT2,LIG4,MYO9A,OCRL,NLE1,PTN,ZSCAN32,RIPOR1,ASAP3,FAM214B,SYNE1,NT5M,PHTF2" Drug 384_DN retinoic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADORA2A,SEMA6A,DOC2A,GAS7,MARK4,RASL11B,CACNA1A,KALRN,CHGB,LY86,GREB1,KLHL3,DRP2,EDNRA,EGR3,ELN,EPHB1,TBC1D16,DLL3,HPGDS,GLYR1,ADAMTS6,IRF8,SCIN,MBD1,RETREG1,MAPK7,RGS12,SH3GL3,ZKSCAN3,SNAP25,ZC3H13,CLASP2,SSTR2,RGL1,TNS1,TRIO,SSBP2,ZNF184" Drug 4560_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "PPP4R4,CDK13,CFLAR,ST3GAL5,IL33,SEPT7,CREM,ENTPD4,NR1D2,EGFR,IRAK4,ETV1,ZNF589,FGFR1,GAD1,DISC1,COPS8,KCNN1,KIF2A,LMO2,SMAD1,TM6SF1,NF1,CNOT4,PFKFB2,LRRN3,GRAMD1C,PTPRN2,TMEM231,HKDC1,SLA,RBM26,SYN2,ZEB1,GPR161,TPM2,SSBP2,WIPF1,REEP1" Drug 5925_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,TRMT9B,SCAPER,CACNA1I,LDLRAD4,CAMK2B,QKI,BAG4,ABCG1,SNCAIP,CSF1R,MFAP3L,CDON,ING4,FGF12,RAB30,GRIK5,ICA1,MSI1,NOVA1,PDE4A,LRP12,PRKAR1B,ZSCAN2,GAL3ST4,KCTD17,ZFHX4,ZFP30,SH3GL3,SLC4A3,PREX2,LIMS2,PKNOX2,RBM34,TSNAXIP1,UNC5B,FAM155A,DNALI1,RNF170" Drug 6153_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "SPARCL1,LTBP4,BIN1,KSR1,FUBP1,CACNA1I,CFAP410,CACNA1B,SEPT7,CHRNA4,LHX2,MFAP3L,HS3ST2,MAMLD1,OPTN,ING4,ETV1,FGF1,CAMKK2,SIGLEC8,GATM,GSTM5,KCNB1,LAMA2,MYT1,NDP,NRCAM,RETREG1,POU6F1,PTPRN2,ABLIM3,ARHGAP26,TBCEL,PCDHA5,TK2,TPM1,KCNK12,PLSCR4,PARP11" Drug 5988_DN Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AMH,ADAM23,ADAM15,CA12,ARHGEF2,VAX2,AKAP7,CREM,CNTNAP2,TBC1D5,GIT2,TOM1,SEZ6L2,ACSL4,ZNF589,USP19,TDRKH,IL6R,IL6ST,INPP5B,ITPKB,MATK,MITF,CNOT4,SLC25A23,PTN,PTPRE,FBXW7,AMBRA1,CXXC4,MAPKBP1,SPTAN1,SPART,EXOC7,IQCE,ZFP37,GDPD5,SEMA3B,PCBP4" Drug 2184_DN Flurandrenolide [1524-88-5]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "NDRG2,BRAP,PPFIA4,APOC1,CAMK2G,CD86,SCARB1,TAOK2,TMEM184B,IQCK,ZNF337,ING4,EIF1,F5,USP19,RAB40B,ICA1,IFI16,MEF2C,SCAMP5,MYT1,NFYA,SLC11A2,PLCB2,PLEC,PILRA,MAPK7,RIPOR1,CEP97,ZCWPW1,RGS3,FBXW7,GALNT10,KIAA1107,PLPPR2,LAT2,TRIM9,EVI5,PHTF2" Drug 4023_UP Metronidazole [443-48-1]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ADD2,CDK10,CDK13,N4BP2L1,ARHGAP33,MAGI1,RAB33A,TPP1,VAX2,AKAP7,AKAP6,AKAP5,LRIG1,CSNK1E,DTNA,EDNRA,NRN1,EFCAB2,NEU3,GLYR1,GRIK5,ICA1,JAK2,KCNJ5,OCRL,PIK3R1,RETREG1,LRP12,BEND5,SLC11A1,PHLDB1,RPGRIP1L,CRTC1,TRO,TUBB1,VIPR2,VLDLR,SLC30A4,PHTF2" Drug 1734_UP Trolox [53188-07-1]; Up 200; 16uM; HL60; HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "MTUS1,FAM131A,ADAM15,CAPN3,KRIT1,CLCN3,FAM189A2,SMARCAL1,SH2B1,PPP6R2,C2CD2L,KLHL3,DTNA,CDKL3,PIPOX,ANKMY1,OLFM1,ALDH1L1,RUNDC3A,ATXN2L,KCNN1,NEFH,OPA1,ZNF426,MBOAT7,MINDY2,CNNM2,ZSCAN32,PTX3,AMBRA1,BTBD3,SZT2,SLC44A1,PLPPR2,REEP1,EVI5,GDPD5,HPS4,MPPE1" Drug 7214_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "APBA2,PDE8B,CFLAR,KSR1,CACNA1G,THSD7A,CAMK2B,CBFA2T2,CNTN1,CRY2,ARHGEF10,CNTNAP2,SPOCK3,RASGRP2,DLC1,FGFR1,GAD1,ALDH1L1,GRM8,TJAP1,IL6ST,INPP5B,JAK2,MSI1,NF1,NPR2,C19orf57,LRRN3,CNKSR2,FAM214B,KANSL3,CXXC4,ATP10B,PHLDB1,TRIM2,RIMBP2,TRO,ITM2C,PHTF2" Drug 7547_DN Ald1.1-H_000455; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "CDK10,SYNJ2,SCAPER,KYAT1,PLEKHB1,TPP1,SULT4A1,HOMER3,NCOR2,PHF14,PPP6R2,SPOCK3,CNNM1,EGFR,RGS17,TRMO,SIGLEC8,INPP5K,COPS8,MSL3,JAK2,MAPT,MX1,NPR2,CCSER2,PTPRH,NEK11,SUPT20H,ZFP30,FAM214B,ZNF667,DDN,ZEB1,RUNDC3B,UGT8,ZNF711,ZNF74,URM1,EPM2A" Drug 2562_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ASIC1,ABHD6,APC,CDK13,SYNJ2,CAMK2G,HOMER3,ARMC8,SIPA1L1,MAML1,SPATA2,EFCAB2,PDLIM5,MSL3,MUM1,MAP4,SCAMP5,GIT1,OCRL,TMEM104,PTCH1,SEC14L1,GALNT10,MRAS,SH3BP2,LIMS2,MYH15,KDM4B,ZHX3,IZUMO4,SPTAN1,DIP2A,EXOC7,TCF4,DMXL2,SZT2,TPM2,PLPPR2,ACTR3B" Drug 6069_DN Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "ALCAM,APBA2,KCNAB2,APBB2,CSF1R,FAM169A,DZIP3,APPL1,RIMS2,PPP6R2,GIT2,DTNA,TOM1,MBNL2,FAM198B,ZNF589,FGFR1,BAIAP2,IQCG,SEMA4D,USP19,TXNL4A,GRB10,HNMT,INPP5B,ITPKB,KPNA5,MAPT,MATK,MYO9A,RETREG1,POLG,WDR25,NKAIN1,SMARCD3,TACC1,TMEM121,ZKSCAN5,VIPR2" Drug 6826_DN Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "LTBP4,KIF1A,CAMK2G,B4GALT6,TAOK2,FAM169A,GIT2,ING4,ANKMY1,EXTL2,FGF12,FGFR1,FGFR3,FHL1,SEMA4D,FAM49B,OGA,TXNL4A,TDRKH,MAP4,MBD1,KITLG,SCAMP5,PLEC,PLXNB1,RPS6KA2,SUPT20H,EPN2,BTBD7,TTC17,SNCA,ZSWIM8,PHLDB1,JMJD6,ARC,KIAA0930,PARD3,TRIO,GDPD5" Drug 3543_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AP2A2,AK2,AMT,ALDH7A1,CFAP410,CA12,CAMK2G,WHRN,CSF1,MFAP3L,RUSC2,NCALD,FER,FLNC,OGA,DISC1,GPER1,GRIK5,ATXN2L,GIT1,NF1,NTRK2,PALM,RETREG1,POLG,PPARA,RGS12,EMID1,SEMA6D,BTBD7,KIF13A,PHLDB1,ARC,ZEB1,TMEM121,PLPPR2,MAP3K12,PCBP4,PHTF2" Drug 6907_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "APOC1,CDC14B,RGS20,MTMR2,CHN2,AATK,ARHGAP24,MFAP3L,RHOBTB1,SEC24B,FHL1,KCNMB4,LIG4,MEIS1,NF1,PALM,SERPINI1,NLE1,CNTLN,PTPRN2,SUGCT,HSPA4L,SH3BP2,AMBRA1,ST6GAL1,SNCA,EXOC7,KIAA1107,TNS2,HEY1,TPM2,SSBP2,HIRA,LMF1,TFIP11,PCBP4,PLSCR4,SMIM8,GAN" Drug 3205_DN Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-04 1.00E+00 4.53E-03 5.11E-02 39 199 "AMPD2,AMT,RGS20,STX16,USP2,SCARB1,QKI,WHRN,SOCS5,DAPK3,DBT,FBXL5,FCF1,HSD17B14,STX2,VPS26C,RASSF8,ATXN2L,AGFG1,KCNH2,MAP4,KITLG,ADAM22,NEK1,NF1,LRP12,PPP5C,GTDC1,NEK11,KDM4C,UNC5B,NXT2,TACC1,TBL1X,ZNF34,KAT6B,NPL,MAP3K12,UBE3B" Drug ctd:C051890 irinotecan CTD 4.70E-04 1.00E+00 4.61E-03 5.19E-02 109 704 "ACHE,AS3MT,AGT,AK2,SRPX,CDC42BPA,MAP4K3,APC,CDK13,NCOA1,ZNF582,BCL7A,BID,CFLAR,PROM1,DST,CACNA1I,CCK,KRIT1,SLC16A4,CDC25B,MAGI1,CLGN,UBE2L6,CLTC,ABCG2,ARMC8,NCOR1,KIAA0040,CTH,DCAF8,MATR3,CDON,FARSB,FCF1,YAF2,EGFR,PAN3,VPS13B,GPHN,ERBB2,ERBB4,DENND4A,F8,DLC1,POLK,UBE2E3,DCTN2,PDLIM5,FYB1,DBF4,LOXL3,TPPP,FRMD5,IGF1,RBPJ,SCIN,HECTD2,MATN2,MBNL1,MBP,MSR1,PCDHGC3,PDE4B,ABCB1,PMP22,PSAT1,ING3,PPP3CA,KANSL1,PRKCB,MAPK3,CNNM2,SAMD9,PTCH1,PTK2,PTPN13,PTPRD,PTPRG,PTPRN,RGS4,SLC25A36,SETD5,HSPA4L,SGK1,SEC31A,BTBD3,NBPF1,COA1,FAM219A,ERC1,POGZ,DIP2A,PLCB1,SYT1,ANKRD28,MCF2L,TCF12,ITGB3BP,SLC44A1,TLR4,CABIN1,DOK6,VLDLR,LMF1,XRCC4,ZBTB14,ZNF32,TRIM9" Drug 332_UP trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.74E-04 1.00E+00 4.64E-03 5.23E-02 37 186 "ACADM,MARK4,BMP7,RAB29,BAIAP3,WHRN,AKAP12,PDE4DIP,ARMCX2,DRP2,SUGP2,MBNL2,STX2,PCYOX1,FYN,CYP46A1,RAB40B,RNFT2,AFF1,MXI1,SERPINI1,CCSER2,PLCD1,ZNF821,SH3BGR,SH3GL3,PPM1E,KIF16B,ASAP3,WDR47,FAM214B,PKNOX2,NXT2,ACTR6,NPL,PLPPR2,MPPE1" Drug 6672_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.74E-04 1.00E+00 4.64E-03 5.23E-02 37 186 "ACHE,AMT,LGR5,CDC14B,CBS,CBFA2T2,MAGI1,NRXN3,HOMER3,PDE4DIP,CTH,RUSC2,DUSP9,EDN1,EPHB1,CSPG5,CACFD1,GSN,ITGA7,KCNJ5,MGAT3,ADAM22,MSR1,NTRK2,PCDH9,PDE4B,LRRN3,PTPRG,GAL3ST4,RGS4,RGS12,HKDC1,SLC2A5,SOX15,KDM4C,LAT2,KCNAB1" Drug 6987_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.74E-04 1.00E+00 4.64E-03 5.23E-02 37 186 "BRAP,EPB41L5,GAS7,PDE4DIP,DBT,SGSM2,MED12,SHANK1,ING4,MALT1,GLYR1,TDRKH,STON1,HNMT,MAP4,MAPT,MBD1,MITF,MXI1,LYRM9,ZNF862,SERPINI1,NECAB2,MAPK7,GTDC1,RFX3,RGS3,SLC6A8,COA1,TSNAXIP1,DOK5,KDM3A,TROVE2,TACC1,TK2,CABIN1,ZNF23" Drug 6831_UP Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.74E-04 1.00E+00 4.64E-03 5.23E-02 37 186 "MARK4,SYNJ1,SCAPER,HIP1R,FAM149A,CABP1,ABI3BP,CPS1,CREM,MBNL2,USPL1,IGSF6,SCARA3,FYN,SEPT9,SRCAP,GPD2,NXPH3,ICA1,IL6R,MIA2,MN1,NOVA2,CDK18,SERPINI1,PRKAB2,KLHDC8A,PEX26,TSNAXIP1,JMJD6,TBCEL,SMG6,WSCD1,UCHL1,ZFAND5,EVI5,FXR1" Drug 3279_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.74E-04 1.00E+00 4.64E-03 5.23E-02 37 186 "MTUS1,STX16,ADAM15,MPDZ,CFLAR,SPAG9,KRIT1,CLCN3,SLC4A8,SOCS5,GREB1,TBC1D5,DBT,FCF1,SUGP2,IRAK4,ANKFY1,ZNF44,GHR,GPR37,IL6ST,ITPKB,MMP16,NFYA,PIK3R1,SLC25A36,ZNF821,TRA2B,ARHGEF9,EXOC7,TBL1X,TRIM2,DICER1,BHLHB9,KAT6B,HIRA,FXR1" Drug CID000001206 MAMP Stitch 4.80E-04 1.00E+00 4.69E-03 5.29E-02 33 160 "ADCY5,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,CALM1,CCK,CRY2,CSNK1E,MED12,DPYSL2,NCALD,PPP1R1B,GABRG2,LOXL3,GRIN2C,GRIN2D,GRM2,MAPT,NPY,OPRL1,PDE1B,PPP3CC,GSTCD,SNCA,DDN,ADHFE1,TACR1,ZEB1,ZMAT3,CSMD1,SLC17A7" Drug 7077_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.80E-04 1.00E+00 4.70E-03 5.29E-02 35 173 "ABHD6,ADRB2,ARNTL,ST3GAL5,CBFA2T2,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,TAOK3,BAIAP2,GUCY1B1,FAM69A,LIFR,MMP16,TAGLN3,PCDH9,SERPINI1,RETREG1,TMEM104,RGS4,FBXW7,FAM102A,ASAP3,FAM214B,KDM4B,DOP1A,ARHGAP26,THSD1,RGL1,PHLDB1,SYT1,KIAA0930,PLSCR4" Drug 7105_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.80E-04 1.00E+00 4.70E-03 5.29E-02 35 173 "ADRB2,APBB2,ARNTL,MARK4,ST3GAL5,SYNGR3,CSNK1E,PDE4DIP,CTH,C2CD2L,PLPPR4,TAOK3,DLC1,BAIAP2,PDLIM5,FYN,MEF2C,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,ENOX1,RBBP6,RGS4,FBXW7,SH3GL3,ASAP3,FAM214B,DOP1A,THSD1,RGL1,SYT1,COBL,SSBP2" Drug CID000157688 vinflunine Stitch 4.82E-04 1.00E+00 4.71E-03 5.30E-02 15 52 "HEPH,EGFR,TUBD1,TUBB3,TUBA8,GPR162,MAP6,MX1,ABCB1,PTK2,TUBB2A,TUBB1,ANKS1B,TUBA1A,EPM2A" Drug CID000002834 AC1L1EKQ Stitch 4.82E-04 1.00E+00 4.71E-03 5.30E-02 15 52 "ADCY5,ADCY6,ADCY8,ADRB2,AMT,ALDH7A1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,PDE3A,PTK2" Drug 3810_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ASPHD1,AMPD3,APC,EPB41L5,ZSCAN18,RASL11B,ATP1A3,NRP2,SCAPER,AKAP7,RCHY1,SH2B1,CSF1,EXOG,DTNA,EDNRA,FGFR1,TRMO,OGA,FYB1,KCNMB4,GRIK5,ICA1,TJAP1,MAPT,MN1,NDP,OGG1,PTPRB,ZCWPW1,RASA3,SH3BP2,OGDHL,ARHGAP26,GPR161,TNS1,HIRA,EPM2A" Drug 4630_DN Hycanthone [3105-97-3]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "CDK13,PDE8B,STX16,ATP2B2,SYNJ2,CACNA1I,CFAP410,SCARB1,RAB28,ABCG2,AKAP7,ARMC8,DZIP3,TBC1D5,DBT,MFAP3L,TOM1,EDNRA,FCF1,ZNF589,GAD1,B4GALNT1,GLYR1,MSL3,CACFD1,HAS2,HNMT,NDP,MBOAT7,PRPH,PTPRN2,TRIM68,ZKSCAN3,KDM4B,TSNAXIP1,NXT2,SZT2,NAV3" Drug 3474_UP Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "SYN3,AP2A2,AK2,GAS7,ARHGDIG,CFLAR,GYG2,CAMK2B,RCBTB2,STOML1,ENTPD4,ABCG1,CSF1R,RUSC2,EGFR,VPS13B,RRAGB,FGFR1,CAMKK2,SRCAP,DIDO1,IL6ST,KCNN1,MAN2A2,NF1,NTRK2,PRKAR1B,RGS12,TCP11L1,RPS6KA2,SMARCD3,SNCA,ZHX3,CDK19,ZBTB43,EXOC7,EVI5,TIGD6" Drug 5437_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ADD2,ADRB2,ADGRF5,BEGAIN,BIN1,ST3GAL5,ARHGAP22,RAB33A,SULT4A1,GREB1,ARHGEF4,PLPPR4,EDN3,ING4,C3orf18,IGSF6,SIGLEC8,GDF9,RUNDC3A,GLYR1,GRB10,SOX21,ADAMTS6,ATXN2L,HMGCR,ICA1,ITPKB,MAP4,MYO7A,PCDH9,LIMCH1,SNCA,NMNAT2,PEG10,JMJD6,TRIM2,R3HDM1,VSNL1" Drug 6422_DN STOCK1N-35215; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "AK2,FAM131A,MARK4,MPDZ,SLIT2,LHX2,RAB28,CRMP1,PDE4DIP,C2CD2L,DLC1,SYT17,STON1,CNTRL,MAP4K5,KHK,MEIS2,NEK1,ZCWPW1,RET,KCTD17,CCDC25,EMID1,DHX30,DOP1A,FNBP1,GLT8D1,SPTAN1,ITPRID2,ST5,ARC,FAM208A,KIAA0930,UBTF,WRN,EMSY,MPPE1,ACTR3B" Drug 262_UP "indomethacin, USP; Up 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ASIC1,KDM5D,BRAP,KCNAB2,ARNTL,CACNA1I,TAOK2,TPP1,PCYT1B,CSF1R,DCAF8,TNK2,ERCC2,EYA1,TRMO,SEPT9,SOX21,FAM107A,ATXN2L,HLF,IRF8,L1CAM,ADAM22,NF1,NNAT,NTRK2,STRN3,MBOAT7,FNDC3A,PPP4R3A,FAM214B,SLC11A1,IFT122,PHLDB1,TEK,TRIO,PLPPR2,WNT7A" Drug 4788_UP Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "RALGAPA1,FZD9,C1QTNF3,AMPD3,GAS7,APOC1,SGCE,SCARB1,ASIC3,PLEKHB1,SLC12A6,EGR3,SPEG,ACSL4,FGF13,ERAP1,GRB10,TJAP1,JAK2,KCNH2,ADAM22,NF1,ZSCAN32,PTPRE,PTPRN2,C1orf54,TRIM68,GSTCD,EMID1,ASAP3,KDM4B,EXOC7,TBL1X,TRIM2,TNS1,CLDND1,SLC30A3,EVI5" Drug 3200_DN Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ABHD6,AK2,FAM131A,SEMA4G,MARK4,SLC4A4,CFLAR,CACNA1I,BAIAP3,KYAT1,SCARB1,CSF1R,CYBB,SPOCK3,MED12,DTNB,EIF4G2,ENO2,FGFR1,FHL1,ZNF44,SRCAP,GFER,PRUNE2,LPAR4,GRB10,GRIK5,MAP4,MIA2,MSI1,NF1,SNRK,PTPRO,FNDC3A,EPN2,LIMCH1,DOCK9,EPM2A" Drug 4161_DN Cefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "AP2A2,NME5,AK2,APBB2,APLP1,ARRB1,PLA2G4C,RASL11B,SYNJ2,CFAP410,RIMS2,GPRASP1,MFAP3L,PARD6A,HIPK3,ING4,SCML2,ZNF589,GCNT2,KCNQ3,IPO5,MAP4,ADAM22,CDK18,PLCD1,PRKAR1B,MAPK10,TRIM68,SLC9A5,KIF13A,THSD1,ST5,MCF2L,TBCEL,WSCD1,TMEM121,PARD3,WIPF1" Drug 4180_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "AGT,APBA2,ATP2B2,SLC2A11,ADAM15,MTMR3,BAIAP3,CALB1,USP2,AKAP7,FAM149A,BAG4,DBT,HEPH,DMPK,ING4,TNK2,MTSS1L,FHL1,ZNF44,SIGLEC8,GFER,RUNDC3A,SOX21,ADAM22,ZNF862,NEFM,NPR2,NTRK2,PID1,SLC11A1,SP4,ATP10B,TCF4,LAT2,ZNF711,SLC17A7,PHTF2" Drug 6717_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ADRB2,PPFIA4,KCNAB2,APC,GAS7,CDK13,CACNA2D1,ARHGAP33,QKI,VCAN,PDE4DIP,CTH,HDAC9,C2CD2L,MTSS1L,SCML2,AMOTL2,EFCAB2,SIGLEC8,ALDH1L1,LILRA2,ATXN2L,ELOVL5,KCNJ5,MX1,MYH3,NOVA2,NTRK2,LRRN3,PTPRH,PTX3,MARCH1,HKDC1,FAM214B,SYT1,TAL1,RPGRIP1L,JPH3" Drug 3807_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "BCAS1,LGR5,CDC14B,ARHGDIG,ADAM23,RGS9,RUNX1T1,SULT4A1,RAB26,AATK,PDE4DIP,HS3ST2,DTNA,EGR3,IGSF6,AGAP2,CAMKK2,ZNF44,CPLX2,STMN2,GRIK5,HLF,ICA1,KCNN2,ADAM11,KITLG,AFDN,GPR85,PPP2R2B,PRKCB,KHDRBS2,RGS4,PKNOX2,ARC,ZFPM2,WIPF1,LAT2,ZNF154" Drug 2131_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ADORA1,BIN1,SEMA4G,CASK,MTMR3,STOML1,CABP1,CRY2,PDE4DIP,USP6NL,DAPK3,CDON,EIF4G2,TUBD1,NBEA,GALC,ZNF276,TJAP1,KCNJ5,MSR1,P2RY1,PGAM2,WDR25,PID1,GAL3ST4,ZMAT4,STUM,MYH15,IZUMO4,ZBTB43,SYN2,DNMBP,TBCEL,ZNF34,SMUG1,FZD3,MARCH8,SENP7" Drug 979_DN ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ABHD6,NDRG3,ARRB1,NCOA1,MPDZ,CFLAR,RAB29,PLEKHB1,LHX2,DCAF8,PARD6A,DPH1,RRAGB,FGFR3,TRAF3IP2,GLYR1,HTATSF1,CNTRL,KCNH2,KHK,MPP2,ADAM22,PKIA,FAM192A,FERMT1,FUZ,ZKSCAN3,SMARCD3,ZBTB43,NXT2,ELOVL4,CEP68,AP4E1,BHLHB9,KAT6B,UBTF,ZNF24,PHTF2" Drug 5629_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "GAS7,PDE8B,MARK4,SYNJ2,GYG2,CACNA1I,SULT4A1,ABCG1,PDE4DIP,ARHGEF4,RIMS2,DCAF4,ARMCX2,MFAP3L,SLC12A6,GLYR1,RAB30,CACFD1,KPNA5,LYRM9,STRN3,GRAMD1C,SUPT20H,ANKRD6,SIRT2,BTBD7,COA1,ZHX3,ANKRD28,KIAA0930,CRTC1,CHST8,CDK20,TRIO,ZFP37,ZBTB14,SLC17A7,SENP7" Drug 901_DN 5114445; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ASPHD1,CDK10,B4GALT6,QKI,RUBCN,KAT8,POLR1B,FGFR3,PRKAG2,EFCAB2,ZNF276,CRCP,GPER1,AGFG1,HSF2,JAK2,MAN2A2,MAP4,NF1,OXTR,PDPK1,RET,ROBO1,SEC14L1,SYBU,DHX30,ERC1,SPTAN1,CLASP2,JMJD6,PRRC2C,TACC1,MCF2L,EXOC7,DICER1,ZKSCAN5,HIRA,EPM2A" Drug 6809_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "AP2A2,AGT,BIN1,AQP6,PPP4R4,SLC2A11,CACNB4,ARHGEF1,TAOK2,ARMC8,NCOR2,RIMS2,DCAF4,EPB41,CDKL3,FLT1,POLL,GPR37,ICA1,KCNN2,MID1,ZNF862,PURG,PPARA,MAPK7,RGS4,TCP11L1,SEMA6D,FAM214B,KANSL3,MAPKBP1,SPP1,SYN2,RPGRIP1L,UCHL1,HPS4,SLC17A7,ITM2C" Drug 3925_DN Deltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ALCAM,LTBP4,FAM131A,PPP4R4,ALDH7A1,MTMR3,CBFA2T2,CNTFR,AKAP7,NECTIN3,CSF1R,DUSP9,EDN1,HIPK3,FCF1,MBNL2,EPB41L2,EZH1,FAM49B,ARFIP1,RUNDC3A,KCNF1,KCNH2,MAP4,KITLG,NELL2,PCDH9,PLCD1,MINDY2,WDR25,ZDHHC14,NEK11,FBXW7,FAM214B,ARC,KIAA1107,ZNF24,PHTF2" Drug 3322_DN Iohexol [66108-95-0]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ADORA2A,SEMA6A,EPB41L5,ARNTL,SYNJ1,CA4,ARHGEF2,RCAN1,DTNA,FCF1,HSD17B14,FER,RUNDC3A,GLYR1,RAB30,GPER1,GRB10,TJAP1,KITLG,GIT1,NEK1,NF1,NFYA,NPTX1,STRN3,ZSCAN32,ZNF493,TCP11L1,FNDC3A,NXT2,STX1A,PLCB1,TRIM2,TMPO,KAT6B,ZNF24,GDPD5,LAS1L" Drug 6733_DN "Zidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ARHGDIG,ARRB2,MARK4,ALDH7A1,KIF1A,ADAM23,WHRN,PPP6R2,MFAP3L,RUSC2,SPOCK3,DNM1,SEMA4D,FYB1,ZNF44,SEPT9,AHDC1,POLL,GPER1,MAPT,ZNF862,MYT1,OGG1,FSD1,MAPK7,KHDRBS2,RGS4,KIRREL1,RXRA,MAPK12,SBF1,ARHGAP26,SPTAN1,PHLDB1,RPGRIP1L,DOCK9,TNS2,TNS1" Drug 2561_DN Dicumarol [66-76-2]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "C1QTNF3,CDK13,ZBTB10,SLC4A4,SCAPER,CD86,QKI,ENTPD4,TM9SF4,DBT,DTNA,FCF1,FCGRT,ANKFY1,MSL3,LILRA2,ICA1,ITGAM,MIA2,SLC11A2,POLR2F,GTDC1,MRPS18A,C12orf49,GSTCD,ZNF331,SEC14L1,GALNT10,ZFP30,NUBPL,ZKSCAN3,CDK19,EXOC7,FBXW11,DMXL2,SSBP2,FLRT2,WIPF1" Drug 4138_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "AMPH,RGS20,MARK4,CFLAR,RUNX1T1,SLC16A4,ABI3BP,NRG2,CSF1R,ARHGEF10,SIPA1L1,RUSC2,HS3ST2,ING4,ERCC2,FGFR1,AFF2,FAM49B,PRELID3A,PRUNE2,GRB10,TAGLN3,NNAT,SAMD9,RGS12,EPN2,BTBD7,ZNF423,IQSEC2,THSD1,TBCEL,SMG6,PCDHGB6,R3HDM1,TRIO,XRCC4,GDPD5,KCNAB1" Drug 3672_DN Clemizole hydrochloride [1163-36-6]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "APC,CDK13,MARCH3,ALDH7A1,NRP2,CA12,HAP1,SCARB1,SEPT7,CNTFR,AKAP7,IQCK,ARMC8,HAPLN1,VCAN,GPRASP1,DBT,DMPK,DUSP9,CACFD1,MAPT,MIA2,PIK3R1,PRKAR1B,DZIP1,COA1,SNCA,KDM4C,TROVE2,SS18,TRIM2,GPR161,BHLHB9,TNS1,LMF1,WNT7A,TRIM9,KAT6A" Drug 2996_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "TRMT9B,SYNJ2,CBFA2T2,CLGN,CLOCK,RUBCN,ZFYVE16,BRINP1,PLXNC1,C3orf18,PIPOX,MEF2C,MGAT3,ENPP2,RETREG1,PTCH1,PTN,ZSCAN32,RET,SEC14L1,MRAS,RASA3,FRMPD1,ARHGEF40,ELMO2,ZNF415,TSPYL2,CEP68,SYT5,EXOC7,PLPPR2,LMF1,REEP1,MAP3K12,EVI5,KCNAB1,FAM13C,PHTF2" Drug 4725_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.94E-04 1.00E+00 4.80E-03 5.41E-02 38 193 "ASPHD1,NME5,EPB41L5,SYNJ2,SOCS6,QKI,SULT4A1,RCHY1,CTH,MAML1,GIT2,EXOG,EDNRB,FCF1,NCALD,FER,ANKFY1,GALC,GLYR1,RAB30,GPD2,IL6ST,KCNH2,MAP2,KITLG,ADAM22,MSR1,CNOT4,SERPINI1,STRN3,LRP12,C1orf54,ZFHX4,ARHGAP26,SS18,TMPO,FLRT2,ZNF24" Drug 3637_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.05E-04 1.00E+00 4.91E-03 5.53E-02 36 180 "BIN1,APBA2,APOC1,CDK13,CACNA2D1,USP2,ARHGEF2,CDO1,CLGN,CHN2,ABI3BP,DPP6,DTNA,ENO2,ERCC2,PTK2B,AMOTL2,OGA,GFER,GRB10,MIA2,CDK18,C1orf54,ZNF821,PPM1E,PKNOX2,PDZD2,KDM3A,UNC5B,SYN2,HIF3A,CHST5,RUNDC3B,VLDLR,LAT2,KCNAB1" Drug 5223_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.05E-04 1.00E+00 4.91E-03 5.53E-02 36 180 "OSBPL1A,AMPD3,BIN1,MPDZ,ST3GAL5,ARMC8,CRY2,PDE4DIP,CTH,SPOCK2,ARMCX2,RCAN1,MBNL2,ING4,RUNDC3A,GRB10,ICA1,IL6R,IL6ST,MAP4,NF1,KLK6,MORC4,TCP11L1,HSPA4L,SGK1,SH3BGR,HECW1,TSPYL2,TRIM2,BEX4,R3HDM1,RUNDC3B,VLDLR,SEMA3B,FXR1" Drug 2348_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "NDRG2,ARRB1,NCOA1,CFLAR,SEPT7,SULT4A1,ENTPD4,USP6NL,SEC14L5,DTNA,COQ7,DLC1,FCGRT,ANKFY1,PDLIM5,INPP5K,LILRA2,SOX21,SLC2A6,PADI2,MAP4,NELL2,NPR2,CCSER2,PMP22,LRRN3,GAL3ST4,TCP11L1,NLGN1,SLC9A5,SNCA,DOK5,PDLIM2,WSCD1,TCF4,ZKSCAN5,UBE3A,LAT2,ADAMTS9" Drug 4787_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ALK,APBA2,APLP1,PPP4R4,BAIAP3,CFAP410,ARHGEF2,FOXN3,CHN2,PLEKHB1,AKAP6,ARHGEF4,JAKMIP2,MFAP3L,EDN1,MBNL2,NCALD,SPEG,ZNF589,FHL1,AGAP2,ERAP1,SIGLEC8,LPAR4,SYNPO,KCNH2,PLCD1,DCHS2,SNRK,SEMA6D,PREX2,KDM4C,UNC5B,PEG10,CDK19,RGL1,TRO,FLRT2,EMSY" Drug 268_UP genistein; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "NDRG2,CBFA2T2,B4GALT6,STOML1,GIT2,FBXL5,DPYSL2,SUGP2,MBNL2,MRNIP,VPS26C,AMOTL2,SEMA4D,LUZP2,LILRA2,ITPKB,ADAM22,OPRL1,PLEC,FSD1,RET,SAFB,SGK1,SH3BP2,FERMT1,FNDC3A,SLC9A5,KBTBD4,RCOR3,IFT122,KDM4B,FNBP1,PEG10,CLASP2,TSC2,LMF1,ZNF23,HPS4,MPPE1" Drug 2116_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ADORA2A,KIF1A,CACNA1I,ARHGAP33,ARMC8,AATK,SLITRK5,RIPOR2,MYEF2,MTSS1L,ETV1,EZH1,GNG4,CACFD1,KCNN1,LMO2,MIA2,MYT1,GPR85,ZSCAN32,PTPRG,ZFP30,BTBD7,KDM4B,ZNF423,SPTAN1,ZBTB43,PHLDB1,MCF2L,EXOC7,TCF4,SYNE1,TIAM1,VIPR2,MAP3K12,EMSY,EVI5,SEMA3B,DPF3" Drug 6687_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ALK,ATP1A3,NRP2,CALB2,SCARB1,TAOK2,RAB28,HAPLN1,MFAP3L,TNK2,FAM198B,ZNF589,FGFR1,ZNF44,GLI2,STMN2,GRM8,IL6R,IL6ST,LSS,MN1,ADAM22,MT1M,NF1,NPTX1,PPP1R1A,ZSCAN32,PTPRN2,RGS12,KCTD17,KLHDC8A,FRMPD1,DZIP1,SLC11A1,SNAP25,TACR1,HIF3A,ZNF225,EVI5" Drug 1722_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "C1QTNF3,AMT,EPB41L5,P2RX6,SCARB1,PICK1,SEC31B,RUBCN,C2CD2L,DPP6,COQ7,RASGRP2,ANKMY1,OLFM1,FGFR1,AFF2,FAM107A,MUM1,MPP2,GIT1,NINJ2,NTRK3,OCRL,RETREG1,RETREG2,MAPK3,MAPK10,DEF8,RGS3,RXRA,AMBRA1,FAM214B,UNC5B,ATP10B,PLCB1,PARD3,PLPPR2,ZNF142,SLC17A7" Drug 3822_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AMPD3,KCNAB2,MARK4,ATP1A3,KSR1,BMP7,SCAPER,CBS,CNTNAP2,RIMS2,CYBB,DAPK3,MYEF2,MFAP3L,SPOCK3,EIF4G2,F5,DLC1,FGF1,SCARA3,SEMA4D,FYB1,GPR75,SPACA9,LAMA2,ZNF862,ZSCAN32,ZSCAN2,ZNF821,SLC2A5,SNCA,DDN,THSD1,TNS1,CDK20,HIRA,VGF,NAV3,PARP11" Drug 4841_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "LTBP4,CDK10,KRIT1,SCARB1,SRSF11,MAP4K4,HOMER3,AKAP7,LRIG1,FAM169A,MFAP3L,MED12,DTNA,FEM1B,SUGP2,HNMT,IPO5,MAN2A2,OGG1,RETREG1,PLEC,RGS12,MAPK12,ZNF821,FERMT1,FUZ,AMBRA1,ZKSCAN3,SMARCA4,CDK5RAP2,TMCC1,ZBTB43,ARHGEF9,ASTN2,EXOC7,TBL1X,MTMR14,HPS4,KAT6A" Drug 6826_UP Amrinone [60719-84-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AMT,EPB41L5,APLP1,APOC1,AZGP1,GYG2,SGCE,CLGN,CNTN1,WHRN,NECTIN3,SPOCK2,RUSC2,COQ7,ERCC2,CDKL3,KAT8,FGF13,HPCAL4,SEPT9,RUNDC3A,AP4S1,HNMT,KIFC3,LSS,ADAM22,MX1,MYCN,CLDN11,PPARA,MAPK7,C1orf54,CARF,HIF3A,UCHL1,LAT2,ZNF23,NT5M,SENP7" Drug 4197_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "C1QTNF3,SEMA6A,SLC4A4,SYNJ1,ST3GAL5,SCAPER,CACNA1I,CAPN3,SCARB1,ARHGAP33,LARGE1,ABCG1,ECM2,EDN3,HIPK3,TNK2,LRRC17,EPHB1,NRN1,OLFM1,GALC,DISC1,TDRKH,AP4S1,NXPH3,LAMA2,MYH3,PLCD1,PTPRN2,GAL3ST4,RFX2,EMID1,OGDHL,KIF13A,TSNAXIP1,SYN2,TK2,TPM1,KCNAB1" Drug 6016_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "BIN1,KCNAB2,MARK4,ZSCAN18,CFLAR,BAIAP3,HAP1,MTMR7,MAGI1,CACNA2D2,PHF14,MAML1,ING4,VPS13B,CORO2B,ST3GAL6,FER,PCDH17,IRF8,KCNH2,KHK,SAMD14,NNAT,ELOVL2,TRIM68,RGS4,SH3BP2,ASAP3,KDM4B,PDZD2,CDK19,SYN2,SZT2,DOCK9,AP4E1,SLC44A1,PARD3,LAT2,ITM2C" Drug 995_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AK2,NCOA1,ATP6V0A1,SRSF11,B4GALT6,RAB28,HOMER3,AKAP7,AKAP12,NCOR1,DBT,DMPK,ING4,SCML2,FGFR3,SYT17,MALT1,HTATSF1,KCNMB4,FERMT2,IPO5,MAP4,MBD1,MMP16,PCDH9,PLEC,LRP12,RETREG2,RXRA,MAPK12,SGK1,EPN2,NSFL1C,ASTN2,IQCE,PCDHA6,LMF1,ZBTB14,PHTF2" Drug 3442_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ALCAM,ATP6V0A1,MPDZ,BCL7A,CFLAR,GYG2,CRLF1,STX2,CDKL3,RRAGB,ZNF589,FGFR1,CSPG5,USP19,MSL3,MATK,TM6SF1,MPP2,GIT1,ADAM22,NEK1,NPTX1,SETD4,MBOAT7,PRKAR1B,ZSCAN2,FERMT1,MAPKBP1,CAMTA2,VPS13A,TNS2,AP4E1,PARD3,CDK20,ZNF74,REEP1,SEMA3B,PCBP4,KAT6A" Drug 4084_UP Moxonidine [75438-57-2]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "SEMA6A,LTBP4,FUBP1,USP2,SLC16A4,KCNAB3,CHN2,VAX2,RGS6,PYGO1,C2CD2L,SPOCK3,EDIL3,RASGRP2,IGSF6,ZNF391,REEP2,GATM,ALDH1L1,GRM8,MMP16,MYCN,NF1,ENPP2,DIRAS2,CCDC40,RNASEL,EMID1,STUM,HECW1,ZC3H13,ARHGAP26,DDN,SS18,TAL1,DICER1,GPR161,KCNAB1,HRASLS" Drug 2664_DN "aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "NDRG2,TRMT9B,PPFIA4,CACNA1G,CACNA1A,PLAA,SPATA2,EIF4G2,ELN,ERBB2,FHL1,FYB1,ZNF44,RUNDC3A,POLL,GRM8,ATXN2L,TJAP1,LSS,MAP4,MAPT,AFDN,MYO6,PDE4A,PLTP,PMP22,SCN2B,RASA3,FRMPD1,NLGN1,BTBD7,SNCA,ARHGAP26,TNS2,VIPR2,LMF1,CLIP2,XRCC4,TIGD6" Drug 282_DN fludrocortisone acetate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "EP400,ARNTL,RGS11,MYRF,TBRG4,CHN1,LHX2,SH2B1,CSF1R,PTK2B,FGFR1,SEMA4D,CGREF1,GNAO1,BTN2A1,SOX21,ICA1,IGF1,KCNJ5,LAMA2,MAP4,MMP17,ADAM22,SETD4,OCRL,RETREG1,PLXNB1,RNH1,PCMTD2,PREX2,SMARCC2,KDM4B,IQCE,TBL1X,BHLHB9,PDIA2,WNT7A,ZNF142,AAAS" Drug 3432_DN Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AP2A2,EPB41L5,EIF4G3,CRLF1,LHX2,QKI,NCOR1,DCAF8,GIT2,STX2,SEPT9,GSN,IL6ST,INPP5B,ADAM22,ZNF862,PDE4A,SMOX,PRPH,ELOVL2,ZCWPW1,FBXW7,FAM192A,SBF1,FERMT1,ABLIM3,PPP4R3A,SMARCA4,SMARCC2,SPTAN1,ANKRD12,CABIN1,LMF1,ZBTB14,NDRG4,ZNF189,MAP3K12,HPS4,SEMA3B" Drug 1969_UP Dibucaine [85-79-0]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "APAF1,ARNTL,CFLAR,MTMR2,GYG2,SLIT2,NCOR1,CSF1R,ARHGAP32,TM9SF4,TBC1D5,ZNF804A,DTNA,TRMO,FYB1,ZNF44,TXNL4A,HNMT,IFI16,KCNN1,KIF2A,NCF2,NTRK3,OXTR,ENPP2,RETREG1,TMEM104,CLIP1,SAFB,CHD9,ARHGEF40,IFT122,ZC4H2,TTBK2,TCF4,TST,ZKSCAN5,NPDC1,RNF103" Drug 2175_DN Dipyrone [5907-38-0]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "RALGAPA1,BRAP,AMPD2,ATP2A2,MTMR2,CACNA1A,SOCS6,C2CD2,ZFYVE16,RUSC2,TNK2,TUBD1,RASGRP2,SCML2,COPS8,ITPKB,JAK2,LIG4,MAP4,NEK1,SLC11A2,CCSER2,ZNF426,POLG,PRKAB2,GSTCD,TCP11L1,ATXN2,RASA3,FAM214B,SNCA,IZUMO4,ZC4H2,PLCB1,PCDHGA10,OBSL1,TPM1,TRPS1,TIGD6" Drug 5432_UP Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ASIC1,ADRA1B,ALCAM,AMPD3,AMPH,PRX,PPP4R4,CACNA1G,BAIAP3,CACNA2D1,CD86,EPS15L1,CYBB,SLC12A6,DTNA,FRY,REEP2,FGF1,PDLIM5,ALDH1L1,PRUNE2,LPAR4,GSTM5,ICA1,IRF8,MMP16,NEFM,NF1,NNAT,CDK18,CEP41,PTPRO,RGS12,RORB,ZNF423,PCDHA5,UCHL1,DNALI1,SLC17A7" Drug 3477_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ABHD6,ALCAM,CDC42BPA,APC,EPB41L5,FAM131A,ADAM15,ST3GAL5,QKI,BAG4,CTH,C2CD2L,CELSR3,PHF20L1,TNK2,DISC1,GCNT2,TXNL4A,RAB30,CNTRL,LSS,MAP4,PTPN13,MSANTD2,NEK11,SMARCC2,MAPKBP1,RBM34,GLT8D1,SPART,THSD1,ELOVL4,TBL1X,BEX4,PARD3,UBTF,LMF1,REEP1,MAP3K12" Drug 2728_UP Butacaine [149-16-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "C1QTNF1,AMPH,APBA2,ARSE,ATP1A3,ADGRB1,USP2,CDH2,LARGE1,CHN2,SV2B,CDON,RASGRP2,DLC1,NSG1,HPGDS,TJAP1,MAPT,MBNL1,TAGLN3,PDE1C,PURG,LRRN3,PPP5C,PKIA,MAPK7,PTH1R,RGS4,RGS12,RPS20,FAM214B,ZNF415,IZUMO4,SYT5,CHST8,LMF1,KLC2,SLC17A7,FAM13C" Drug 2704_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "FGD2,RGS20,SYNGR3,EPS15L1,DZIP3,ZNF337,INTS1,DAPK3,PARD6A,MBNL2,AASS,TNK2,SRPK3,VPS13B,RASGRP2,FER,PDLIM5,MSTN,PRUNE2,LILRA2,ATXN2L,ITGAM,LSS,NINJ2,POLG,PPP5C,MAPK7,MAPK10,DCHS2,RGS12,PKNOX2,SLC11A1,FAM189A1,ICAM5,RIMBP2,TRO,TRPS1,EVI5,PHTF2" Drug 6839_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "NDRG2,AMPH,GAS7,SEMA4G,SLC4A4,SLC2A11,LDLRAD4,CACNA1A,HIP1R,EPS15L1,SULT4A1,RUSC2,CDON,EDNRA,HIPK3,MBNL2,COQ7,ERCC2,ZNF44,SIGLEC8,GCNT2,LPAR4,PCLO,TJAP1,ITPKB,MEF2C,MID1,MSI1,ADAM22,ZNF862,LRRN3,RIPOR1,TMEM231,RFX2,TCP11L1,ASAP3,HECW1,WSCD1,ZKSCAN5" Drug 2197_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "RALGAPA1,ABHD6,AMPD3,APBB2,APC,APOC1,KIF1A,CAMK2G,LARGE1,CSF1,DTNA,TOM1,PIPOX,PTK2B,CRCP,POLL,GNG4,MAP4,OCRL,PILRA,MAPK3,CNTLN,RIPOR1,FAM184A,PLPPR3,SEC14L1,ZNF821,SLC6A8,SLC11A1,MAPKBP1,KDM4B,TSPYL2,DDN,ADGRL3,PCDHGA10,PARD3,PLPPR2,VSNL1,ZNF225" Drug 4073_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "LGR5,ADGRB2,BCHE,THSD7A,CAMK2B,RUNX1T1,USP2,STOML1,PICK1,AKAP5,RCHY1,HAPLN1,CSF1R,LRIG1,IPCEF1,SPOCK3,HIPK3,MRNIP,PRELID3A,GNG4,GPD1,SOX21,PDE4A,ENPP2,MASP1,PTCH1,RGS4,EMID1,SH3BP2,SLC2A5,SLC14A1,RBM26,TCF4,DOCK9,SLC19A3,AP4E1,CHST5,KCNAB1,PHTF2" Drug 6032_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "KDM5D,SEMA6A,BIN1,AMT,SLC4A4,CALB1,TAOK2,SNCAIP,SPOCK2,EBI3,HSD17B14,FGFR1,AGAP2,AFF2,FYB1,CPLX2,GFER,GPR37,CACFD1,HLF,C2orf72,KCNJ5,ADAM22,TAGLN3,MASP1,RFX2,ZNF821,ST6GAL1,OGDHL,MYH15,SNCA,UNC5B,ARHGAP26,ATP10B,RGL1,PCDHGA10,PDIA2,HRASLS,JPH3" Drug 2077_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "MTUS1,AMPD2,SEMA4G,CDK13,ADGRB2,SYNJ2,RAB28,CLTB,CNTNAP2,DCAF4,DAPK3,GIT2,EXOG,CDON,DTNB,MAMLD1,IRAK4,MFSD10,COQ7,ANKMY1,BAIAP2,SPACA9,CACFD1,ICA1,INPP5B,MX1,ZFYVE21,PLEC,PLXNB1,PKNOX2,ZNF415,IQSEC2,LHPP,MCF2L,EXOC7,NSD1,CABIN1,LAT2,AAAS" Drug 6033_DN Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "RALGAPA1,ASIC1,ADRA1D,FAM131A,CDC14B,ARHGEF7,CACNA1I,USP2,CBFA2T2,ARHGEF2,TAOK2,RCHY1,CSF1,RASSF2,SLC12A6,TOM1,ZNF589,IQCG,FYB1,SYT17,SRCAP,INPP1,KCNH2,SMAD1,ZNF862,NLE1,SLC25A23,MBOAT7,TCP11L1,RPS6KA2,ASAP3,BTBD7,IQSEC2,TSPYL2,THSD1,VPS13A,DICER1,TK2,KCNAB1" Drug 4075_DN Metrizamide [31112-62-6]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "RALGAPA1,CDC42BPA,GAS7,APOC1,PPP4R4,DNAH17,SYNJ1,CNTFR,FAM169A,ARHGAP32,DAPK3,DBT,MFAP3L,DTNA,EDN1,FCF1,FAM13A,PLXNC1,IRAK4,ZNF549,FGF1,KPNA5,MGAT3,NOVA2,RETREG1,PRKAR1B,ZSCAN32,SH3TC2,MAPK12,CSRNP3,LIMS2,CCDC88A,SS18,CEP68,SZT2,CHST8,CABIN1,WIPF1,XRCC4" Drug 5996_DN Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AK2,APBB2,APLP1,MTMR3,ARHGEF2,HOMER3,ARMC8,ENTPD4,CSF1R,CNTNAP2,ZFYVE16,SGSM2,ANKMY1,KAT8,ZNF589,FAM49B,USP19,IL6R,MAP4,NFYA,NPR2,CCSER2,PRKAR1B,SAMD9,PTPRG,GTDC1,TRAPPC13,SGK1,AMBRA1,FAM214B,SPTAN1,LHPP,PLCB1,DNMBP,TK2,ZKSCAN5,TFIP11,MAP3K12,GDPD5" Drug 1235_UP genistein; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ALK,BIN1,GAS7,CDC14B,ZSCAN18,NCOA1,ALDH7A1,KIF1A,GYG2,C5,ARHGEF2,TAOK2,RAB28,AKAP7,CPS1,HAPLN1,TM9SF4,DPH1,HIPK3,SRCAP,GLI2,TDRKH,GSN,NF1,NTRK2,PFKFB2,PRKAR1B,WDR25,PTN,MCMBP,SUPT20H,SLC4A3,SNCA,KIF13A,PIK3R5,HIRA,UGT8,PHTF2,AAAS" Drug 5395_DN Aminophylline [317-34-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "C1QTNF3,DOC2A,APOC1,CFLAR,HOMER3,BAG4,CREM,CRY2,SIPA1L1,PDE4DIP,TBC1D5,JAKMIP2,C2CD2L,LYPD1,MRNIP,IQCG,TRMO,AHDC1,GLYR1,GPER1,GRIK5,HNMT,ICA1,IPO5,MITF,RETREG1,LRP12,PRKAR1B,ELOVL2,SH3BP2,FNDC3A,EPN2,SPTAN1,THSD1,SS18,TTBK2,PLCB1,RUNDC3B,LMF1" Drug 2988_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "C3orf14,ATP2B2,CLGN,AKAP7,FAM149A,BRINP1,SGSM2,C3orf18,EPB41,RASGRP2,PIPOX,DLC1,EFCAB2,INPP5K,GATM,ALDH1L1,AHDC1,ADAM28,LILRA2,MAPT,MAPK7,ZSCAN32,ZCWPW1,ZDHHC14,RGS3,MAP6D1,RASA3,NLGN1,SPART,CEP68,SYT5,TNS1,TPM1,TRO,LMF1,SEMA3B,PCBP4,FAM13C,JPH3" Drug 6349_UP Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "BIN1,SEMA7A,SEMA4G,PPP4R4,ARRB2,DNAH17,SCAPER,LARGE1,RCBTB2,B4GALT6,AKAP7,ENTPD4,CNTNAP2,ARHGAP24,MFAP3L,DTNA,IRAK4,EZH1,FGFR1,SCARA3,CSPG5,RUNDC3A,GLYR1,GPER1,CACFD1,KCNJ5,NF1,NTRK2,PLCD1,KIF16B,SLC9A5,SLC11A1,CEP68,EXOC7,TBCEL,TRIM2,UCHL1,VGF,SEMA3B" Drug 6092_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "RALGAPA1,LTBP4,AMH,BIN1,PROM1,GYG2,CDH2,CSF1,HS3ST2,SHANK1,MBNL2,HSD17B14,RASGRP2,ERCC2,PTK2B,AFF2,RASL10A,PRUNE2,STON1,GRB10,GUCY1B1,PGAM2,PLTP,PPP5C,PRKCB,C1orf54,RPS6KA2,SLC11A1,CDK19,SYT5,KIAA1107,ZEB1,SZT2,DOCK9,PIK3R5,UBE3A,WIPF1,LAT2,FAM13C" Drug 2677_DN chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "MPDZ,CAST,PLAA,HOMER3,SH2B1,C2CD2L,TOM1,DNAJB6,E2F5,FRY,PLXNC1,ELN,PTK2B,SEPT9,MSL3,GPD2,LSS,MAPT,MIA2,NFYA,MINDY2,MAPK3,DEF8,TMEM231,GSTCD,ZNF671,SLC6A8,SIRT2,KBTBD4,MAPKBP1,SS18,ARHGEF9,TBL1X,TNS2,R3HDM1,PIK3R5,CDK20,TPM2,CLIP2" Drug 7156_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "BIN1,MARK4,CFLAR,SYNJ2,TAOK2,WHRN,HAPLN1,IPCEF1,PDE4DIP,HDAC9,GIT2,DRP2,YAF2,FAM13A,FGF1,BAIAP2,SEMA4D,TRMO,PDLIM5,FYB1,SEPT9,GLI2,GUCY1B1,IRAK3,INPP5B,JAK2,OPRL1,PLCD1,MBOAT7,CNNM2,PTPRE,TMEM231,KHDRBS2,KIRREL1,ERC1,BHLHB9,R3HDM1,WIPF1,RNF170" Drug 3991_DN Carbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "APBB2,LGR5,CDK10,ALDH7A1,ARHGEF1,TAOK2,LHX2,WHRN,SH2B1,CRMP1,AATK,SLITRK5,DTNA,EGFR,PLXNC1,SPEG,ST3GAL6,ANKFY1,AFF2,TRMO,ICA1,LMO2,MAPT,GIT1,PTPRB,PID1,ZCWPW1,RXRA,FRMPD1,FAM214B,SLC22A4,ZNF667,ARC,TK2,RIMBP2,CABIN1,TRIO,RPRM,EVI5" Drug 2459_UP Nitrofural [59-87-0]; Up 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ADORA1,CDC42BPA,LGR5,N4BP2L1,KIF1A,BMP7,CACNA1I,CDH2,STOML1,CREM,DAPK1,HIPK3,MBNL2,MRNIP,RASGRP2,KAT8,OLFM1,GNAL,ACOT7,HSF2,AFF1,P2RY1,TREM2,PGAM2,PLCD1,PLXNB1,GDPD2,PTN,PTPRN2,PID1,ARHGEF40,ZC3H13,ATP10B,CLSTN2,NXT2,DMXL2,RPGRIP1L,TUBB1,KCNAB1" Drug 604_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ASIC1,MTUS1,APBA2,RAB29,CFAP410,CALB2,HAP1,PTBP2,SEPT7,CNTFR,CDC42BPB,ENTPD4,SUGP2,MBNL2,ZNF589,FGFR1,GRIN2C,SOX21,RNFT2,MAP4K5,KIF2A,MMP16,NACA,CNOT4,SLC25A23,SMIM7,PTPN13,SUSD4,RFX2,ZFHX4,TCP11L1,ZFP30,KIF16B,TMCC1,RBM26,PCDHA6,CHST8,SLC17A7,AAAS" Drug 6029_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "AGT,C1QTNF1,SEMA6A,BIN1,CDC42BPA,RASL11B,CACNA2D1,CAMK2B,RUNX1T1,CD86,WHRN,MYRIP,SNCAIP,ERC2,ELMO1,HSD17B14,CAMKK2,FYN,PCDH17,RUNDC3A,ADAMTS13,GRM2,ATXN2L,CDK18,PFKFB2,ZNF493,RGS12,EMID1,RASA3,SLC8A1,KDM4B,SPP1,TBCEL,CRTC1,TNS1,VLDLR,LAT2,NT5M,NLRP3" Drug 1869_UP Naproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ACTN1,ALK,BIN1,CDC42BPA,KCNAB2,APOC1,NCOA1,BMP7,CA12,CBFA2T2,FOXN3,RUBCN,TUBD1,ZNF589,CAMKK2,BTN2A1,IFI16,MAP4,N6AMT1,MAPK7,RIPOR1,ZCWPW1,GSTCD,SEC14L1,SH3BP2,SLC2A5,FAM214B,IZUMO4,TROVE2,SS18,VPS13A,EXOC7,TBL1X,SIN3B,SYNE1,TPM1,EMSY,PHTF2,ACTR3B" Drug 2134_UP Sparteine (-) [90-39-1]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ADORA1,C1QTNF3,BIN1,APAF1,FUBP1,SOCS6,SPOCK2,SV2B,OPTN,FAM13A,MBNL2,VPS13B,STX2,FHL1,CAMKK2,GALC,ADAM28,PADI2,ICA1,TJAP1,IL6ST,MAP4,MEF2C,SLC25A23,PPP2R2B,WDR25,PTPN13,ZFHX4,ANKRD6,PEX26,SNAP25,ARHGAP26,SPTB,TSPYL2,CEP68,TBCEL,AP4E1,LMF1,SLC17A7" Drug 1237_DN fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.13E-04 1.00E+00 4.93E-03 5.56E-02 39 200 "ARRB2,SLC4A4,BCHE,CA12,CCNT1,SOCS6,QKI,CNTNAP2,FAM169A,DZIP3,KIAA0586,DBT,KIAA0753,LYPD1,PARD6A,SPEG,FGF1,TRMO,CGREF1,PRRC2B,GPR37,GUCY1B1,MAN1B1,HSF2,MATN3,MEIS1,NDP,LRP12,PRPH,RAD51D,ASAP3,SPTAN1,TROVE2,CAMTA2,COBL,KIAA1107,LAT2,EVI5,EPM2A" Drug CID000005673 AC1Q646P Stitch 5.14E-04 1.00E+00 4.95E-03 5.57E-02 14 47 "PDE8B,ALDH7A1,CALM1,KRIT1,KCNB1,KCNH2,KCNQ3,PDCD2,PDE1C,PDE4B,PDE4D,PDE1B,ENPP2,KCNAB1" Drug ctd:C063302 KN 62 CTD 5.14E-04 1.00E+00 4.95E-03 5.57E-02 14 47 "CAMK2A,CAMK2G,NCOR2,EDN1,EDN3,EDNRB,PPARGC1A,ITGAM,MEF2C,P2RX7,ENPP2,MAPK3,SYN1,NLRP3" Drug CID000004938 propentofylline Stitch 5.26E-04 1.00E+00 5.06E-03 5.70E-02 11 32 "ADORA1,ADORA2A,APLP1,ALDH7A1,BCHE,HAPLN1,GDA,EPB41,ITGAM,SMUG1,VIPR2" Drug 5854_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.27E-04 1.00E+00 5.07E-03 5.71E-02 37 187 "ADCY6,NRP2,CFAP410,CBFA2T2,WHRN,AKAP12,CSF1R,VCAN,CTH,MFAP3L,ZNF589,GNAO1,GPD2,LPAR4,GRIK5,KIFC3,MAPT,MIA2,ADAM22,GPR85,SMOX,PPP5C,MAPK7,PTPRH,TMEM231,PID1,PNMA8A,TCP11L1,FAM214B,KIF13A,KDM4B,ATP10B,COBL,PCDHGA10,TRIO,VGF,SLC17A7" Drug 345_UP 2-propylpentanoic acid; Up 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Up 5.27E-04 1.00E+00 5.07E-03 5.71E-02 37 187 "BIN1,AMT,BMP7,RAB29,BAIAP3,SPAG9,CBFA2T2,STOML1,ARHGEF10,PDE4DIP,GIT2,JAKMIP2,MBNL2,CDKL3,EXTL2,TAOK3,ZNF589,FGFR1,BAIAP2,FYN,CYP46A1,RAB40B,STON1,GRB10,TM6SF1,PDE4A,SERPINI1,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,SIRT2,AGTPBP1,TRIM2,BEX4,RNF170" Drug 3851_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.27E-04 1.00E+00 5.07E-03 5.71E-02 37 187 "KRIT1,SMARCAL1,ZBTB24,RHOBTB1,SACS,ANKRD46,EGR3,ARMCX1,TBC1D16,RNFT2,JAK2,MEIS1,THYN1,PDCD2,PIK3R1,RETREG1,ZSCAN32,ERI2,ROBO1,TCP11L1,ZFP30,TMCC1,ZNF302,CEP68,KANK1,ZC3H4,ARHGEF9,ASTN2,MCF2L,FAM208A,TBL1X,SMUG1,ZIC1,ZNF23,HPS4,MPPE1,SMIM8" Drug 4364_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.27E-04 1.00E+00 5.07E-03 5.71E-02 37 187 "SYN3,NDRG2,BIN1,APBA2,N4BP2L1,CACNB4,CRMP1,VCAN,RCAN1,ELN,CORO2B,FYN,GAD1,DISC1,ATXN2L,IRF8,KCNH2,KCNJ5,NTRK3,PGAM2,PLTP,PDZRN4,CNKSR2,IZUMO4,ATP10B,SSTR1,ZC4H2,STX1A,WSCD1,ZEB1,DNAH7,TK2,R3HDM1,HIRA,XRCC4,EMSY,JPH3" Drug 1614_DN Hycanthone [3105-97-3]; Down 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Down 5.27E-04 1.00E+00 5.07E-03 5.71E-02 37 187 "OSBPL1A,ALCAM,CDC42BPA,LRBA,FOXN3,CSF1,CTH,TBC1D5,ELMO1,DTNA,VPS13B,FYN,PRRC2B,KCNN2,MITF,MX1,MYO5A,NACA,NEFH,NF1,MBOAT7,PTK2,GTDC1,MRPS18A,RPS6KA2,SLC2A5,SLC11A1,KDM4C,ERC1,UNC5B,ATP10B,RGL1,SUPT5H,VPS13A,TCF4,PIK3R5,PDSS2" Drug ctd:D003633 Dichlorodiphenyl Dichloroethylene CTD 5.28E-04 1.00E+00 5.07E-03 5.71E-02 54 303 "ACADM,ACTN1,ALK,DOC2A,AMPD3,DPP10,APAF1,BID,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CAMK2B,CAMK2G,CD86,CD38,CDH2,ABCG2,CLOCK,CREM,CASP8AP2,DPP6,EGFR,ERBB2,ERBB4,RACK1,FOXO3,FOLH1,FYN,PPARGC1A,STMN2,GRIA2,IGF1,KIT,NCF2,NF1,NFE2L2,NRCAM,NTRK2,ABCB1,MAPK3,RELN,PTCH1,RDX,RET,ROBO1,RXRA,HES6,NLGN1,UNC5B,STXBP1,SYP,THRA,TSC2" Drug CID000002520 verapamil Stitch 5.34E-04 1.00E+00 5.12E-03 5.77E-02 80 490 "ABCF1,ASIC1,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,ABCD2,MYH7B,KCNAB2,APOC1,APOC2,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CCK,KRIT1,CACNA2D2,ASIC3,CHRNA4,CLCN3,ABCG2,COL4A5,ABCG1,BOC,ABCC5,EDN1,EDN3,EDNRA,EGFR,ABCA8,PTK2B,ATP2C1,GCNT2,MSTN,KCNMB4,MAP4K5,IGF1,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNJ16,KCNN1,KCNN2,KCNN3,KCNQ3,MYH3,MYO5A,MYO6,ABCB1,PIK3C2A,PKD1,PRKCB,RNH1,RYR3,AP1AR,SCN7A,MYO18A,SLC22A4,SPP1,SST,APOM,TPCN2,KCNE5,KCNT2,KCNAB1" Drug CID011984575 2 rF2 Stitch 5.34E-04 1.00E+00 5.13E-03 5.77E-02 18 69 "ARSE,DDR1,DMD,TENM1,MFSD10,ERCC2,ACSL4,AFF2,LIG4,MX1,RAD17,FNDC3A,SYN2,PJA1,SMG6,SYNE1,XRCC4,FTSJ1" Drug CID000082320 1-EBIO Stitch 5.43E-04 1.00E+00 5.20E-03 5.86E-02 12 37 "SLC4A4,CACNA1A,CACNA1B,KCNMB4,KCNN1,KCNN2,KCNN3,LSS,MAP4,PRPH,RPS6KA2,PEG10" Drug CID000016886 5-aza-2'-deoxycytidine Stitch 5.46E-04 1.00E+00 5.20E-03 5.86E-02 100 639 "NDRG2,BRAP,PCDH10,BIN1,APAF1,APBA2,APC,CCAR2,DYNLL1,ATP2A2,KIF1A,CFLAR,CDH2,CLGN,AKAP12,NCOR1,LRRC3B,HDAC9,HDAC4,RASSF2,DAPK1,SCRN1,DAPK3,SPOCK2,BRINP1,MYEF2,GSDME,WDR20,HS3ST2,SHANK1,TOM1,ABCC5,E2F6,EDIL3,CNNM1,EBI3,EGFR,EMX2,TUBB3,DLC1,ST3GAL6,ZMYND10,FGF14,AFF2,SYT3,IQGAP2,ZNF559,SEPT9,GPR162,FAM107A,CPT1C,IRF8,IFI16,ITGAM,MAT2A,MBD1,MBP,LRP1B,MEF2C,SAMD14,MX1,NNAT,NOVA2,PAX6,ABCB1,FSD1,IRX1,KLK6,PTCH1,PTPRG,RASGRF2,ROBO1,ROBO2,EPHA10,SMPD3,LIMS2,SMARCC2,SNRPN,SST,ERBIN,SMG6,ZEB1,SLC35G2,DICER1,TSC1,RPRM,UBE3A,UCHL1,WNT7A,PCDH20,MKRN3,ZNF177,PRTFDC1,SEMA3B,HRASLS,AMN1,FZD3,MSRB3,FXR1,AP3B2" Drug 2185_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ATP2A2,ADAM15,CFAP410,CBR1,SCARB1,CLGN,HOMER3,CSF1,ZFYVE16,ZNF337,RCAN1,OGA,SRCAP,TXNL4A,POLL,PRRC2B,SLC2A6,MUM1,KPNA5,LSS,MYT1,ENPP2,CCSER2,TMEM104,ZSCAN32,CEP97,TCP11L1,SBF1,CCDC88A,ELMO2,TMCC1,KDM4B,SS18,NSFL1C,SIN3B,DMXL2,LAMP5,EVI5" Drug 2284_DN Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,NDRG2,NME5,LTBP4,AMPD3,APBA2,SYNJ2,GYG2,RCBTB2,PLEKHB1,CNTN1,DCAF8,JAKMIP2,DUSP9,FGF12,ANKFY1,SRCAP,GLYR1,POLL,GRIK5,GSN,MBD1,KITLG,ADAM22,MYT1,NFYA,RETREG1,PLCD1,PPP5C,PTN,CEP97,ELMO2,LIMCH1,PLCB1,TRIM2,VLDLR,ZFP37,SENP7" Drug 3988_DN Cinchonine [118-10-5]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,ADORA2A,APOC1,MADD,ARRB2,SYNJ2,RAB26,PICK1,MFAP3L,PLPPR4,CDON,MBNL2,ENO2,ETV1,DLC1,ST3GAL6,ZNF589,MSL3,POLL,SHISAL1,ITPKA,MBD1,MN1,ADAM22,PRKAR1B,WDR25,ZCWPW1,SUGCT,FRMPD1,ASAP3,SMARCD3,TSNAXIP1,DDN,THSD1,THRA,LMF1,KCNAB1,UBE3B" Drug 5418_UP Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,LTBP4,ALK,APC,PLA2G4C,ST3GAL5,CFAP410,FAM189A2,QKI,CPS1,ARHGEF4,DMPK,DTNA,DENND4A,ETV1,FGFR1,KHDRBS3,PCDH17,CNTRL,ATXN2L,ITPKB,KCNJ5,LIG4,LRP12,PRKAR1B,PTN,ZFHX4,TCP11L1,ZNF821,STUM,PEX26,PKNOX2,PDZD2,PLCB1,TBCEL,ZNF34,NT5M,TIGD6" Drug 3783_UP Ethisterone [434-03-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ALK,PKP4,APAF1,BCAS1,CDC14B,KALRN,SYNGR3,ARHGAP33,LARGE1,RIMS2,SV2B,SPOCK3,SRPK3,RASL12,KAT8,OLFM1,AGAP2,ZNF44,GPD2,SPACA9,GRIK5,SOX21,KPNA5,NF1,PDE4B,KCTD17,PKNOX2,SLC6A11,SLC11A1,KDM4C,TROVE2,SZT2,CRTC1,R3HDM1,TUBB1,ZFP37,EMSY,EVI5" Drug 7260_DN Ethamivan [304-84-7]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "BIN1,MADD,MPDZ,CFLAR,WHRN,NCOR1,DCAF8,GIT2,DBT,SPATA2,KIAA0753,SGSM2,TMCC2,TNK2,ST3GAL6,POLR1B,POMT1,PDLIM5,FAM49B,TPK1,ARFIP1,HTATSF1,CACFD1,BTN2A1,RNFT2,HNMT,IFI16,KHK,TAGLN3,SETD4,CCSER2,MINDY2,TMEM104,MCMBP,SMARCC2,DOP1A,CABIN1,GDPD5" Drug 263_UP clofibrate; Up 200; 150uM; MCF7; HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "BRAP,ARNTL,ATP6V0A1,BCL7A,SYNJ2,CACNA1I,CFAP410,KALRN,CAMK2A,TAOK2,DCAF8,DRP2,TNK2,ENO2,ANKMY1,SEPT9,TXNL4A,SOX21,FAM107A,ATXN2L,HLF,IRF8,L1CAM,MX1,NCF2,NF1,NNAT,POLG,SH3TC2,EMID1,FNDC3A,SLC11A1,ST5,FAM155A,PLPPR2,LAMP5,MAP3K12,MPPE1" Drug 7098_DN 0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "RALGAPA1,PPFIA3,BCL7A,HOMER3,WHRN,DCAF4,ZFYVE16,GIT2,APH1A,EPB41L2,ERBB2,ETV1,FAM49B,TRAF3IP2,SRCAP,FERMT2,GUCY1B1,FAM69A,MAP4,MITF,NPR2,SETD4,MCMBP,AMBRA1,PEX26,ZBTB43,TSPYL2,DIP2A,SYNE2,ARHGEF9,EXOC7,PDLIM2,TBL1X,MGRN1,NR2C2,HIRA,EMSY,ACTR3B" Drug 7492_DN semustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADRA1D,ADRB2,BIN1,APC,ARRB1,ALDH7A1,CHN1,CHRNA4,TAOK2,LHX2,COL9A3,NRG2,DCAF4,RUSC2,EDNRA,ANKMY1,ANKFY1,SYNPO,HNMT,KHK,GIT1,MX1,PFKFB2,PTX3,PID1,RAD51D,CSRNP3,WDR47,BTBD7,ZNF667,MYH15,SPATA7,SP4,SPTB,TCF4,BEX4,ZBTB38,SEMA3B" Drug 4839_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADRA1D,AK2,PPFIA3,ARRB1,ARRB2,MARK4,CFLAR,SCARB1,RAB28,WHRN,PDE4DIP,ARHGAP32,DCAF8,DBT,FCF1,CRCP,MAP4,MIA2,NF1,RETREG1,PRKAR1B,PTPRE,SAFB,SH3BP2,SLC22A4,TMCC1,SPART,TROVE2,CAMTA2,PHLDB1,NSFL1C,MTCL1,IQCE,RUNDC3B,CLDND1,NDRG4,URM1,SMIM8" Drug 4798_UP Propantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AK2,KCNAB2,APC,SEMA4G,RIPK1,CFLAR,CFAP410,CAMK2B,ZMYM4,RAB33A,COL9A3,NECTIN3,PUM1,DBN1,DMPK,DTNA,EDNRB,ENO2,DLC1,ZNF589,BAIAP2,PDLIM5,RASSF8,KCNH2,NF1,NPR2,SLC25A23,LRRN3,MRAS,FRMPD1,PPP4R3A,BTBD7,ZHX3,ZBTB43,SS18,EXOC7,SMG6,WSCD1" Drug 7036_DN Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,BRAP,AP2A2,CDC42BPA,BCAS1,EIF4G3,BCL7A,CFLAR,LHX2,RAB28,IQCK,NCOR1,LYPD1,PARD6A,CDON,COQ7,ANKMY1,DISC1,POLL,TDRKH,LIG4,MITF,PLXNB1,STRN3,PTK2,RPS6KA2,SUPT20H,SH3BP2,FERMT1,EPN2,ZHX3,IQSEC2,SPART,CEP68,JMJD6,TMEM121,RPRM,TIGD6" Drug 4573_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "PPP4R4,DNAH17,FUBP1,BAIAP3,USP2,ARHGEF2,CNTFR,CREM,SH2B1,CSF1,CNTNAP2,ARHGEF4,DMPK,ETV1,REEP2,PTK2B,KAT8,FGF1,FGFR1,FGFR3,FLT1,GRIK5,LIG4,MAN2A2,ADAM11,AFF1,NF1,PIK3R1,RETREG1,MINDY2,RGS4,MCMBP,TSNAXIP1,SOX15,UNC5B,SLC44A1,CDK20,SLC17A7" Drug 2299_UP Kawain [500-64-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NME5,ALK,GAS7,PRX,PTCH2,CAMK2B,WHRN,KLHL3,CALCRL,SPEG,ZNF589,OLFM1,FOLR2,SIGLEC8,DISC1,SEPT9,GFER,LYVE1,IFI16,KIF5A,LRP1B,MSI1,NEK1,CCDC40,ZMAT4,RFX2,CNKSR2,ARC,SZT2,TPM2,CHST5,FAM155A,LAT2,SPHK2,ADAMTS9,KCNAB1,HRASLS,SENP7" Drug 6208_UP Dienestrol [84-17-3]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASPHD1,AP2A2,AK2,SEMA6A,BIN1,CA12,CLCN3,BAG4,DZIP3,DAPK3,MFAP3L,PARD6A,EGR3,ZNF589,GAD1,TJAP1,INPP5B,KCNN1,MPP2,ZNF862,SMOX,POLG,ELOVL2,FAM184A,ZDHHC14,RGS4,SGK1,SYBU,ABLIM3,LIMCH1,TRIM2,ZNF34,FAM155A,VIPR2,MAP3K12,SEMA3B,MPPE1,ACTR3B" Drug 4973_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADORA2A,DOC2A,CFLAR,SYNJ2,SCAPER,DZIP3,TBC1D5,MED12,DTNA,MAMLD1,EDNRA,HIPK3,EIF5,COQ7,BAIAP2,PRELID3A,INPP5K,GLYR1,POLL,GRIK5,ATXN2L,MAPT,MBD1,MPP2,GIT1,NF1,PDE4A,PLCD1,PTPRE,ZNF821,BTBD7,SMARCA4,VPS13A,ASTN2,KIAA0930,TRIM2,VIPR2,KAT6A" Drug 4804_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASPHD1,ASIC1,ABHD6,AP2A2,LTBP4,CDC14B,ARRB2,PDE8B,CFLAR,MTMR3,HAP1,SPAG9,ARHGAP33,LHX2,ABCG1,ARHGEF4,DCTN1,ZNF804A,RCAN1,DTNA,ENO2,MSL3,PRRC2B,DHX35,KHK,IPO5,AFDN,PLEC,SAMD9,RIPOR1,KCTD17,FUZ,KIF13A,LHPP,PHLDB1,ZNF34,SLC44A1,NDRG4" Drug 4763_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AP2A2,NME5,LTBP4,AMH,APLP1,CFLAR,CA12,CAMK2G,ARHGAP33,LHX2,NCOR2,GREB1,RIMS2,STX2,DLC1,ST3GAL6,AGAP2,AFF2,MSL3,GRM8,KCNF1,MEF2C,ADAM22,ZNF862,MYT1,NNAT,NKAIN1,ZNF821,SLC6A8,CCDC88A,ZC3H13,DMXL2,SZT2,TMEM121,CABIN1,TNS1,FAM155A,UPF3A" Drug 6467_DN Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AP2A2,SEMA6A,TRMT9B,AMPD3,APBA2,PLA2G4C,RIPK1,ADAM15,SIPA1L1,ZNF337,EGFR,PRRC2B,KCNF1,IPO5,LYRM9,NELL2,NF1,NFYA,PDE4B,LRP12,ELOVL2,TMEM231,KHDRBS2,MAPK12,SBF1,ATXN2,ZNF821,FAM214B,LIMCH1,TROVE2,ARC,HEY1,TK2,CABIN1,HIRA,LMF1,ZNF74,SEMA3B" Drug 7354_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,CDC42BPA,APOC1,PPFIA3,CDK13,CFLAR,ST3GAL5,SYNJ2,SCAPER,SCARB1,MAGI1,QKI,ENTPD4,CSNK1E,GPRASP1,DBT,LYPD1,COQ7,ANKMY1,KAT8,ANKFY1,GLYR1,MSL3,ITPKB,KCNH2,MAN2A2,STRN3,PTCH1,RAD51D,GSTCD,SH3BP2,CLASP2,CEP68,ASTN2,IQCE,CLASP1,MAP3K12,KCNAB1" Drug 2114_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADORA2A,KCNAB2,APC,ATP2B2,ADGRB2,CCNT1,PICK1,DBT,CELSR3,MTSS1L,EZH1,DCTN2,DLL3,DISC1,SRCAP,SPIN1,GLYR1,GNAL,GNG4,TPPP,INPP5B,SMAD1,GIT1,MT1M,CNOT4,OPRL1,PDE4B,MAPK7,PTPRH,RGS4,ZBTB43,TBL1X,SYNE1,TPM1,HIRA,EMSY,SEMA3B,SLC17A7" Drug 1146_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,NDRG2,AP2A2,MTUS1,BIN1,PDE8B,LDLRAD4,CBFA2T2,HOMER3,SIPA1L1,TM9SF4,ZNF804A,KIAA0753,GSDME,DTNA,MBNL2,TRMO,MEF2C,SCAMP5,ADAM22,MX1,NF1,NINJ2,CNOT4,PLCD1,NECAB2,POLG,TCP11L1,RXRA,BTBD7,CEP68,CRTC1,SLC44A1,PARD3,TNS1,HIRA,FLRT2,NPDC1" Drug 3870_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "KIAA1324,ALCAM,APBB2,APC,GAS7,ADGRB1,RHBDL1,CCK,ARHGEF1,CSF1,RUSC2,VPS13B,USP19,RASSF8,ICA1,ITPKA,MAPT,MATN3,MMP16,ADAM22,NF1,PPARA,CEP41,ZSCAN32,RGS12,RPS6KA2,EMID1,RPS20,ZFP2,SH3GL3,IZUMO4,TBCEL,TCF4,PCDHA5,HIRA,LAT2,XRCC4,KAT6A" Drug 7497_DN CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,ADD2,SEMA4G,BACH1,SCAPER,CA4,KALRN,KCNAB3,QKI,SNX29,HIPK3,PLXNC1,FGFR1,FHL1,FLNC,TRMO,TXNL4A,CRCP,GLYR1,GNG4,PRDM5,MAP4K5,HSF2,IL6R,INPP5B,OPRL1,MBOAT7,DCUN1D2,GSTCD,PKNOX2,SMARCD3,PLCB1,ANKRD12,DOCK9,SLC30A4,EPM2A,SMIM8,RNF170" Drug 4678_UP Haloperidol [52-86-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASPHD1,ADCY6,ADGRF5,LTBP4,CDK10,KIF1A,ADGRB1,CACNA1A,TPP1,AKAP5,C2CD2L,DMPK,ETV1,FGFR1,SIGLEC8,GLI2,CACFD1,SCIN,ADAM11,MYH3,NF1,P2RX7,PDE4D,MINDY2,PPP5C,RGS12,EMID1,SLA,ZNF334,ZHX3,IZUMO4,SPTB,IQSEC2,SYN2,TAL1,DOCK9,TUBB1,SLC17A7" Drug 3308_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AK2,APC,PPP4R4,CFLAR,SGCE,CAMK2B,CBFA2T2,FOXN3,CSF1,GREB1,RIMS2,RIPOR2,DTNB,DUSP9,MBNL2,VPS26C,POLL,ATXN2L,HLF,C2orf72,IL6ST,ITGAM,KCNN1,C19orf57,PRKAR1B,PRKCB,KCTD17,RASA3,SNCA,SS18,PHLDB1,DMXL2,RPGRIP1L,KCNK12,ZNF74,PRDM10,GJC2,JPH3" Drug 3377_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,AK2,LTBP4,BIN1,CDC42BPA,SEMA7A,APC,EPB41L5,FAM131A,CFLAR,GYG2,LDLRAD4,FOXN3,STOML1,QKI,HIPK3,FEM1B,EGFR,SPEG,FAM49B,OGA,GPR37,ATXN2L,IL6ST,KCNJ5,PALM,PCDH9,COA1,KIF13A,RBM34,ZNF423,SS18,TACC1,SMG6,TRIO,KCNK12,ZNF24,REEP1" Drug 6767_DN Leucomisine [17946-87-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "EPB41L5,CDK10,PLA2G4C,ATP6V0A1,SYNGR3,B4GALT6,SLIT2,ARMC8,CREM,AKAP12,ARHGEF10,DCAF8,ZNF337,RGS17,STX2,BAIAP2,CELF1,OGA,SRCAP,ACOT7,DHX35,INPP5B,MAPT,MBD1,NACA,NFYA,PCDH9,TMEM104,FAM184A,PPP4R3A,EPN2,ARHGAP26,LMF1,ZBTB38,REEP1,MARCH8,SMIM8,PHTF2" Drug 3811_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,LTBP4,APAF1,GAS7,GYG2,MYRF,CFAP410,CDO1,CHN2,B4GALT6,NRXN3,CRY2,NCOR2,DAPK1,EDIL3,ETV1,NEU3,SRCAP,IL6R,KITLG,AFDN,NF1,P2RY1,PPP2R2B,ELOVL2,PTPRG,ZMAT4,KLHDC8A,ZNF821,CNKSR2,KANSL3,BTBD7,NXT2,MCF2L,DMXL2,DOCK9,SPHK2,PRDM10" Drug 3680_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NME5,CDC14B,ASPA,SLC2A11,NRP2,CACNA2D1,CAMK2B,CHN2,AKAP12,ERC2,ARHGEF4,SPOCK2,HEPH,HS3ST2,EGFR,CDKL3,ETV1,NRN1,FGFR3,GNAL,GRIK5,NXPH3,IL6R,JAK2,LYRM9,NF1,LRRN3,PID1,MYH15,HECW1,ZC3H13,SSTR2,MCF2L,HEY1,TNS1,HIRA,SLC17A7,KCNAB1" Drug 3193_DN Mebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASPHD1,LTBP4,DNAH17,MARK4,ATP6V0A1,CFLAR,TAOK2,FAM189A2,HOMER3,PDE4DIP,HSD17B14,KAT8,FYN,POLL,GNG4,GRB10,HNMT,KCNH2,MEIS1,NEK1,CNOT4,SLC25A23,POLG,RGS12,FNDC3A,RBM34,ZBTB43,ST5,ELOVL4,TACC1,ANKRD12,EXOC7,PCDHA5,THRA,ZKSCAN5,EVI5,HPS4,TIGD6" Drug 3779_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADRA1D,CDC42BPA,STX16,ADGRB2,MTMR2,CBFA2T2,LHX2,PICK1,CNTNAP2,CDKL3,ETV1,TRMO,HSF2,TJAP1,NF1,NFYA,CNOT4,PDE4D,NLE1,SLC25A23,RGS4,NEK11,ASAP3,PEX26,RBM34,ARHGAP26,ATP10B,NXT2,EXOC7,TCF4,CRTC1,DNAH7,TMPO,TNS1,XRCC4,SPHK2,REEP1,DPF3" Drug 606_DN (+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AMT,CDK10,ADGRB1,CFLAR,GYG2,CCK,PLEKHB1,ENTPD4,PDE4DIP,FEM1B,BAIAP2,DCTN2,FOLR2,SYT17,MALT1,GNAO1,BTN2A1,SMAD1,SETD4,OGG1,TREM2,PCDH9,PLCD1,PLXNB1,CEP41,ELOVL2,TTC13,RGS12,KBTBD4,DBNDD2,SEPT8,RGL1,STX1A,COBL,TBL1X,THRA,VSNL1,WNT7A" Drug 3606_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,MTUS1,APC,EPB41L5,APLP1,CFLAR,BMP7,ARHGAP33,RCHY1,ENTPD4,DAPK3,DTNA,HIPK3,PHF20L1,FGF12,FGFR1,GPD2,GSN,DHX35,KITLG,NF1,PCDH9,RGS12,SLC25A36,FNDC3A,PPP4R3A,TACC1,TBCEL,IQCE,KIAA0930,TRIM2,TMPO,HIRA,UBE2H,HPS4,MPPE1,KAT6A,PHTF2" Drug 6102_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "LTBP4,ALK,SEMA4G,ARSE,ADGRB2,SCAPER,CAST,CLGN,HOMER3,AATK,CSF1,SPOCK2,TNK2,EFCAB2,FUT9,SRCAP,ADAMTS13,PRDM5,GRM8,GSN,KCNH2,KCNJ5,KCNN2,SMAD1,NOVA2,PFKFB2,PPP5C,RGS12,ASAP3,CPEB3,PKNOX2,ATP10B,SYP,SYT5,ZEB1,UBE3A,UGT8,WIPF1" Drug 7196_DN Kaempferol [520-18-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NCOA1,NUMB,CREM,SH2B1,MED12,SUGP2,RGS17,FGFR3,EFCAB2,GPR37,HSF2,ICA1,RBPJ,MEIS1,NEK1,PLXNB1,MBOAT7,PRKAR1B,SBF1,GALNT10,WDR47,KDM4B,UHRF1BP1L,ZBTB43,CEP68,TACC1,TNS2,SIRT1,BEX4,KAT6B,SSBP2,ZKSCAN5,PLPPR2,VAV1,SPHK2,MAP3K12,MARCH8,ACTR3B" Drug 3344_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,LTBP4,FAM131A,ATP6V0A1,GYG2,CA4,SLC16A4,RAB33A,CSF1R,RIPOR2,DGKG,DBT,HIPK3,FRY,MBNL2,ERCC2,ZNF589,FGF13,FHL1,OGA,GLYR1,GNAO1,MGAT3,MMP17,MSR1,NF1,PDE1C,STRN3,LRP12,PTPRH,TRIM68,ASAP3,FNDC3A,COA1,KDM4B,ZNF423,DMXL2,SPHK2" Drug 6076_DN Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "APBA2,PPFIA3,CBFA2T2,CNOT8,HOMER3,CNTN1,CRY2,MAML1,ARMCX2,DMPK,DTNA,MBNL2,ING4,STX2,ANKMY1,IQCG,FAM49B,SEPT9,GCNT2,GRB10,CACFD1,KCNF1,LMO2,MAP4,TM6SF1,MID1,LYRM9,NF1,PRPH,FAM184A,SYBU,SLC6A8,UNC5B,THSD1,PLCB1,PARD3,VGF,ZNF45" Drug 6518_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,ABHD6,BIN1,APC,APLP1,SEMA4G,C5,VAX2,AKAP7,WHRN,BAG4,CREM,HINFP,SOCS5,PDE4DIP,FAM169A,DBT,LYPD1,EGFR,B4GALNT1,GRIK5,ELOVL5,IL6R,RIPOR1,TRAPPC13,ZNF821,SUPT20H,KIF16B,ZC3H13,SS18,NXT2,EXOC7,CDK20,SSBP2,UBTF,XRCC4,ZBTB14,MAP3K12" Drug 6774_DN Anabasine [494-52-0]; Down 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ALCAM,APBB2,CDK10,NUMB,ARHGEF7,SCAPER,CBFA2T2,TAOK2,ABCG1,CSNK1E,CTH,DTNA,TOM1,SCML2,FGFR1,SMC2,FAM49B,INPP5K,MAP4K5,ELOVL5,NF1,NNAT,CCSER2,RETREG1,ZSCAN32,FAM184A,ZNF821,SOX3,CLSTN2,ELOVL4,ARC,TNS2,BEX4,CDK20,LMF1,XRCC4,SEMA3B,EPM2A" Drug 3166_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "DOC2A,ATP6V0A1,BCL7A,CAMK2G,FAM189A2,SH2B1,ABCG1,PARD6A,HSD17B14,EPB41L2,STX2,EZH1,SEMA4D,ZNF44,GALC,USP19,RNFT2,HNMT,MATK,NFYA,SLC25A23,MINDY2,PTPRE,RIPOR1,BTBD7,IQCE,CRTC1,CHST8,ZNF34,NPL,ZKSCAN5,HIRA,RPRM,VIPR2,ZNF74,HPS4,EPM2A,UBE3B" Drug 3676_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "APAF1,BCAS1,SPTBN4,PDE8B,N4BP2L1,ADAM23,BMP7,CACNA1I,CFAP410,CHGB,CHN2,SUSD5,CNTNAP2,DGKB,SHANK1,SNX29,RGS17,ETV1,ABCA8,FGFR1,ERGIC3,RUNDC3A,ATXN2L,HLF,KIFC3,MBP,AFDN,NF1,MINDY2,KHDRBS2,CARF,PDZRN3,NFASC,SLC44A1,PDIA2,ZNF154,KCNAB1,EPM2A" Drug 3280_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AP2A2,GAS7,MARCH3,B4GALT6,RAB28,PLAA,QKI,NECTIN3,CSF1R,SOCS5,PPP6R2,DCAF4,OGA,GPD2,MUM1,GIT1,NPR2,NPTX1,LRP12,RIPOR1,RGS12,FBXW7,RPS6KA2,EMID1,CLIP1,FERMT1,FNDC3A,ZBTB43,CLASP2,THSD1,ANKRD12,TRIM2,AP4E1,TRIO,WIPF1,ZBTB14,ZNF24,KCNAB1" Drug 1814_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ABR,ADGRF5,AMPD2,CDK10,MARK4,BID,CA12,SCARB1,LHX2,CSF1,PPP6R2,EZH1,SCML2,FGF1,FGFR1,BAIAP2,CGREF1,GAD1,SYT17,DISC1,SRCAP,USP19,SLC2A6,KIFC3,MX1,SLC25A23,FA2H,BCAS3,MCMBP,SUPT20H,FAM214B,IFT122,TRIM2,HIRA,LMF1,UPF3A,EPM2A,PHTF2" Drug 3288_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "APAF1,APC,CDC14B,PPP4R4,SLC2A11,CFLAR,LDLRAD4,CBFA2T2,CDO1,SLIT2,AKAP7,CSF1,DUSP9,MBNL2,EIF4G2,PIPOX,ZNF589,GATM,SRCAP,GLYR1,TM6SF1,NNAT,NTRK2,CLDN11,PLTP,CXXC4,ZSWIM8,RBM26,SYN2,WSCD1,TRIM2,SYNE1,ICAM5,CHST5,LAT2,SLC30A3,NT5M,PLSCR4" Drug 2485_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ASIC1,NDRG2,ANK2,ARRB1,ATP2A2,ADAM23,SYNJ2,CAPN3,CBR1,STOML1,C2CD2,CSNK1E,CTH,HDAC9,TM9SF4,DTNA,PCOLCE2,KAT8,CSPG5,SEPT9,INPP5K,GRB10,LSS,MAP4,P2RX7,TRHDE,PTCH1,TMEM231,RAD51D,RNASEL,SEC14L1,SLC11A1,ZNF667,DDN,SEPT8,TNS1,ATP6V0E2,URM1" Drug 6380_DN STOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "LTBP4,APBB2,APOC1,STX16,ADAM15,FUBP1,GYG2,CNTNAP2,ERC2,DCAF4,C2CD2L,DTNA,FCF1,EGFR,COQ7,ETV1,ZNF589,FGF1,FGFR1,ANKFY1,CPLX2,GRIK5,IRF8,NEK1,NTRK2,PLEC,MINDY2,RGS12,ASAP3,SLC11A1,IQSEC2,DDN,TCF4,DMXL2,TPM2,HIRA,NT5M,SENP7" Drug 4411_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ALCAM,APBB2,PDE8B,MARK4,NCOA1,ST3GAL5,SLIT2,LHX2,RAB26,SH2B1,AKAP12,RIMS2,DBN1,MFAP3L,DNM1,HSD17B14,FGF13,BAIAP2,DISC1,PCLO,KCNN1,KHK,MAN2A2,MMP16,ADAM22,NF1,RIPOR1,RGS12,CEP68,PHLDB1,WSCD1,DMXL2,ZNF34,HIRA,FLRT2,ZNF74,EMSY,KAT6A" Drug 4361_DN Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "AP2A2,MTUS1,AK2,SEMA6A,ADAM15,SYNJ2,FAM169A,DAPK3,NR1D2,TSPAN5,EIF4G1,COQ7,ERCC2,NCALD,AGAP2,SPIN1,GLYR1,STON1,IL6ST,INPP5B,MAP4,MMP16,ZNF862,NEK1,PIK3R1,GRAMD1C,SLC25A36,SEC14L1,SH3BP2,ZBTB43,PRRC2C,TBL1X,KIAA0930,DICER1,USP1,PLPPR2,ZNF24,ZBTB38" Drug 3522_DN Imidurea [39236-46-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "ADD1,BIN1,CDC42BPA,CDK13,RASL11B,KIF1A,CFLAR,CAMK2G,ABI3BP,CSF1,LRIG1,DZIP3,MFAP3L,LYPD1,MED12,PHF20L1,SUGP2,MBNL2,SCML2,SEPT9,TDRKH,HNMT,KCNH2,KIF2A,MEIS1,ADAM22,LYRM9,NEK1,MBOAT7,PPP5C,CEP97,ZFP30,ZHX3,SPTAN1,ZNF34,LMF1,SEMA3B,SMIM8" Drug 3527_DN Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "CDC42BPA,PPFIA3,CDC14B,ARRB1,MARK4,CAMK2G,SOCS6,B4GALT6,TAOK2,HOMER3,NCOR1,CSF1,GREB1,RCAN1,TOM1,MBNL2,EIF4G2,FHL1,FLNC,FAM49B,GALC,JAK2,KCNH2,MID1,SMOX,PRKAR1B,PRODH,TMEM104,DCUN1D2,UNC5B,PHLDB1,EXOC7,RPGRIP1L,SLC44A1,PLPPR2,SPHK2,SEMA3B,KAT6A" Drug 7089_DN lomustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "SRPX,CASK,CDK13,KIF1A,SYNJ2,MTMR2,MAGI1,RAB26,HOMER3,WHRN,PDE4DIP,DZIP3,E2F5,EIF5,ARMCX1,DLC1,SYT17,SRCAP,MALT1,ZNF276,GPER1,JAK2,MBNL1,MPP2,ADAM22,PRODH,SUSD4,FERMT1,AMBRA1,SMARCA4,SPATA7,CDK19,CEP68,TACC1,ANKRD12,KAT6B,ZBTB14,SEMA3B" Drug 2213_DN Ivermectin [70288-86-7]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "NDRG2,SEMA4G,CDK13,MARK4,SYNJ2,GYG2,CAMK2G,MAGI1,TAOK2,SLIT2,LHX2,DBN1,ZNF589,FGFR3,TMEM164,MALT1,RAB30,GPER1,GPR37,ITPKB,KCNH2,LMO2,MAP4,PCDH9,CDK18,PMP22,NKAIN1,RET,NEK11,ATXN7,ANKRD6,EPN2,SLC6A8,CEP68,SLC44A1,TIAM1,REEP1,EMSY" Drug 3302_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "KIAA1324,APLP1,ARHGAP33,SULT4A1,CNTN1,CRMP1,BRINP1,JAKMIP2,MFAP3L,DMPK,DRP2,HIPK3,PLXNC1,ZNF589,SRCAP,RAB30,GPER1,ATXN2L,KCNQ3,MAPT,ZNF862,PLCD1,PLXNB1,CNNM2,KCNIP1,FAM214B,SLC11A1,SNCA,TBCEL,SLC19A3,CRTC1,CABIN1,PDIA2,VIPR2,ZNF189,DNALI1,EVI5,SENP7" Drug 4285_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-04 1.00E+00 5.20E-03 5.86E-02 38 194 "BRAP,APBB2,CBFA2T2,SEPT7,HOMER3,WHRN,HAPLN1,CRY2,PDE4DIP,CNTNAP2,FAM131B,RUSC2,FAM13A,RGS17,ETV1,ANKMY1,EZH1,BAIAP2,FLT1,PDLIM5,FYN,SRCAP,POLL,SHISAL1,PALM,WDR25,TMEM231,SBF1,SPTAN1,ZBTB43,TSPYL2,ELOVL4,ARHGEF9,ASTN2,KIAA1107,TNS1,LAT2,NDRG4" Drug ctd:C070417 Win 55212-2 CTD 5.48E-04 1.00E+00 5.20E-03 5.86E-02 16 58 "ADORA2A,ARHGDIA,CNR1,EGFR,VPS26C,GCK,MAP2,MAPT,MAT2A,TAGLN3,PPARA,MAPK3,MAPK9,PTPRN,WDR47,NDRG4" Drug 1786_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.69E-04 1.00E+00 5.39E-03 6.07E-02 32 155 "NDRG2,BIN1,ARRB2,CFLAR,LDLRAD4,CREM,PPP1R16B,DOCK4,GOLT1B,MBNL2,EIF5,ING4,DCTN4,ACSL4,GLUL,IRAK3,AGFG1,AFF1,PDE4B,PDE4D,SATB1,ATXN7,SEC14L1,SGK1,FNDC3A,SLA,SLC12A2,ELMO2,SAMSN1,CEP68,SSBP2,FLRT2" Drug CID000000765 9-beta-D-arabinofuranosylguanine Stitch 5.69E-04 1.00E+00 5.39E-03 6.07E-02 127 845 "ACTN1,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADRB2,AGT,NME5,APLP1,ARHGDIA,PDE8B,ALDH7A1,RGS11,ARHGEF7,CACNA1B,SLC25A14,ARHGEF25,CCK,KRIT1,ARHGEF1,ENTPD2,LRBA,ARHGEF2,CDR1,RAB33A,RAB28,MYL6B,CLTC,LETMD1,ENTPD4,GDA,RGS6,LRIG1,PLCXD3,GPSM1,CYBB,DOCK4,RHOBTB1,PARD6A,DNM1,SLC29A4,DOCK2,DNM1L,EDN1,RASGRP1,RASA4,TUBD1,TLR7,RRAGB,GMPR2,TUBB3,BAIAP2,POLK,AGAP2,AGAP3,RASL10A,IQGAP2,TUBA8,ARFIP1,BRD8,RAB40B,GNAL,GNAO1,LPAR4,MCHR1,GRIA2,PLCD4,CIT,GUCY1A1,GUCY1B1,TNFAIP8L3,SYNPO,MAPT,MX1,NCF2,NF1,NME4,NPY,NPR2,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PIK3R1,PLCB2,PLCD1,POLG,PPP1R1A,PRKACB,PRKCB,MAPK3,RELN,PTK2,RAP1GDS1,REV3L,RGS4,RGS12,RNASE1,GSTCD,MRAS,NAPB,SNAP25,SNCA,HECW1,SST,NSFL1C,PLCB1,MCF2L,EXOC7,TBL1X,SMG6,TIAM1,TK2,ACTR6,METTL3,TRIO,TSC2,TUBB2A,TUBB1,VAV1,TUBA1A,PLD4" Drug 4018_UP Niclosamide [50-65-7]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.70E-04 1.00E+00 5.40E-03 6.08E-02 34 168 "ZSCAN18,ZBTB10,CARS,CBS,ARHGEF2,CTH,HDAC9,NR1D2,ECM2,EGFR,RGS17,ZNF391,PRELID3A,OGA,FERMT2,CACFD1,IFI16,IL12A,MIA2,PDE4D,PTX3,BEND5,RGS4,SLC25A36,GSTCD,AP1AR,CPEB3,ZBTB43,ANKRD12,HEY1,CDK20,VIPR2,ZNF24,DPF3" Drug CID000165791 lanthanum chloride hydrate Stitch 5.70E-04 1.00E+00 5.40E-03 6.09E-02 9 23 "ADRB2,ATP2A2,ATP2B2,CALM1,RGN,ATP2C1,MAP4K5,P2RY1,P2RY12" Drug CID006442177 everolimus Stitch 5.83E-04 1.00E+00 5.52E-03 6.22E-02 29 136 "BRAP,PARD6A,EGFR,ERBB2,RRAGB,RPS6KC1,EVL,CAMKK2,PPARGC1A,IGF1,KCNH2,KIT,MBP,NPY,ABCB1,PIK3C2A,PIK3R1,PPP3CA,PPP3CC,RPS6KA2,TRERF1,MLST8,ALG1,CRTC1,CABIN1,PIK3R5,TSC2,UBTF,RICTOR" Drug 6735_DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.86E-04 1.00E+00 5.55E-03 6.25E-02 37 188 "CDC42BPA,PKP4,CDC14B,STX16,SPAG9,SLIT2,QKI,FAM169A,TBC1D5,DAPK3,DBT,EGFR,EIF4G1,SPIN1,FERMT2,GPD2,PCLO,AGFG1,IFI16,IL6ST,MAP4,MBP,MYO6,NEK1,PDE1C,SLC25A36,AP1AR,SEC14L1,PEG10,TROVE2,PRRC2C,TBL1X,ZEB1,DICER1,KAT6B,USP1,ZNF24" Drug 4385_UP Thiostrepton [1393-48-2]; Up 200; 2.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.86E-04 1.00E+00 5.55E-03 6.25E-02 37 188 "BIN1,APAF1,SEMA4G,ATP2B2,BMP7,BAIAP3,CFAP410,CALB2,TAOK2,SULT4A1,CREM,NCOR2,CSF1,INTS1,ELN,C3orf18,RASGRP2,DLC1,HPCAL4,EFCAB2,GAD1,GRB10,SYNPO,IL6R,AFDN,PALM,ENPP2,RGS4,FAM214B,SNCA,SP2,SPTB,SYT5,DOCK9,UCHL1,VLDLR,KCNAB1" Drug 5702_UP GBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.86E-04 1.00E+00 5.55E-03 6.25E-02 37 188 "NDRG2,KIAA1324,MTMR3,KALRN,HAP1,RAB33A,PPP1R16B,RIMS2,SPATA2,EDNRA,EGR3,ING4,COQ7,FGF13,FOXF2,GRM8,GSN,NXPH3,IRF8,INPP5B,KCNJ5,KPNA5,ADAM11,NLE1,PLCD1,PPP5C,RASGRF1,TCP11L1,ZNF821,SLC2A5,FAIM2,MCF2L2,SAMSN1,JMJD6,TNS1,VLDLR,SPHK2" Drug CID000012685 DEMP Stitch 5.93E-04 1.00E+00 5.61E-03 6.32E-02 6 11 "ACHE,BCHE,DMTF1,NBL1,PIK3C2A,SARS" Drug CID000032348 BPD I Stitch 5.93E-04 1.00E+00 5.61E-03 6.32E-02 6 11 "ARHGDIG,DNM1,SNAP25,SNCA,SYP,PDIA2" Drug CID000014491 "1,6-hexanedithiol" Stitch 5.93E-04 1.00E+00 5.61E-03 6.32E-02 6 11 "ABHD6,DMPK,DTNA,GCK,SNCA,ADHFE1" Drug CID000004345 arachidonoylglycine Stitch 5.93E-04 1.00E+00 5.61E-03 6.32E-02 6 11 "CACNA1I,CACNA2D1,CBS,CNR1,E2F6,ADHFE1" Drug CID000065065 N-acetyl-L-aspartate Stitch 5.94E-04 1.00E+00 5.61E-03 6.32E-02 24 105 "FZD9,APLP1,APOC1,ASPA,CACNA1A,CACNA2D1,CHRNA4,CNR1,AKAP5,CST3,GTF2IRD2,FOLH1,IL12A,LIFR,MAPT,MBP,IFT122,SPP1,SYP,NPL,CLIP2,ZIC1,GJC2,GAN" Drug CID000003206 EHNA Stitch 5.96E-04 1.00E+00 5.64E-03 6.35E-02 21 87 "BRAP,ADORA1,ADORA2A,AMPD2,AMPD3,APC,NT5C3B,ALDH7A1,ENTPD2,DNAH9,GUCY1B1,NBL1,NPR2,PDCD2,PDE1C,PDE3A,PDE4B,PDE4D,PDE1B,DDN,SLC17A7" Drug 5417_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.99E-04 1.00E+00 5.66E-03 6.38E-02 35 175 "NME5,ST3GAL5,BAIAP3,CLGN,AKAP12,PDE4DIP,ARMCX2,TMCC2,OPTN,FAM13A,RASGRP2,FYN,CYP46A1,STON1,MITF,MXI1,SERPINI1,GRAMD1C,PRPH,SH3GL3,ASAP3,WDR47,PKNOX2,SMARCD3,ELOVL4,RGL1,STXBP1,ZEB1,TRIM2,HEY1,NPL,RUNDC3B,SLC30A3,SLC17A7,ITM2C" Drug CID000003244 AC1L1FHZ Stitch 6.01E-04 1.00E+00 5.67E-03 6.39E-02 41 215 "ALK,APAF1,BACH1,CACNA1A,CACNA1B,NOG,EPS15L1,CNR1,TRIM69,HDAC9,DYNC1I1,DNM1L,EGFR,ENO2,PPP1R1B,GHR,PPARGC1A,TCERG1,GPR37,PACSIN2,HP,IGF1,PACRG,NACA,OGG1,OPA1,ABCB1,MAPK9,MAPK10,PSMA6,QDPR,FBXW7,ATXN7,FOXRED1,SNAP25,SNCA,SIRT1,TLR4,UBC,PRTFDC1,JPH3" Drug 1069_UP 15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.04E-04 1.00E+00 5.68E-03 6.39E-02 33 162 "CDC14B,ARNTL,BACH1,CARS,ARHGEF2,CREM,DNAJB6,EIF5,USPL1,FAM49B,FYN,B4GALNT1,GRB10,MUM1,MBP,SMOX,PRKAB2,RBBP6,MORC4,SLC25A36,RNASEL,TRA2B,HSPA4L,SH3BGR,PPM1E,PPP4R3A,ZBTB43,TSPYL2,JMJD6,TRIO,UBE2H,ZFAND5,FXR1" Drug 3470_DN Securinine [5610-40-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASPHD1,APBB2,PPFIA3,SYNJ2,CFAP410,RAB26,CRY2,CSNK1E,PDE4DIP,FAM169A,HDAC4,C2CD2L,PARD6A,SGSM2,DTNA,EZH1,F8,ZNF589,INPP5K,MUM1,PADI2,SLC11A2,RETREG1,RETREG2,PKIA,NKAIN1,MAPK12,ZKSCAN3,SMARCC2,ELOVL4,TACC1,IQCE,TPM1,CDK20,LMF1,XRCC4,NDRG4,MAP3K12" Drug 2770_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "SPARCL1,PPFIA3,ST3GAL5,SYNJ2,CACNA1I,HAP1,SLC16A4,CPS1,SH2B1,CRMP1,PHF14,DBN1,TMCC2,DTNA,CNNM1,ZNF589,GCNT2,STON1,CNTRL,GRB10,TJAP1,MAP4,PLTP,PPP3CC,PPP5C,PRKCB,RPS6KA2,SLC2A5,BTBD7,CXXC4,LIMCH1,TSNAXIP1,HECW1,TBCEL,SZT2,PCDHA5,LMF1,NT5M" Drug 4820_DN Gabazine [105538-73-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "MTUS1,PPFIA3,CDK10,CASK,NUMB,ADAM15,SYNJ2,CNOT8,RAB28,ARMC8,PDE4DIP,USP6NL,TBC1D5,KIAA0753,LYPD1,PARD6A,MSL3,FERMT2,BTN2A1,RNFT2,HNMT,MBNL1,NRCAM,PLEC,PTCH1,RAD51D,FERMT1,PDZRN3,ERC1,ITPRID2,SYT1,FBXW11,BEX4,UBTF,LMF1,CLDND1,SH3GLB2,FTSJ1" Drug 4198_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "MTUS1,TRMT9B,APC,ARHGAP22,RGS6,ARHGEF10,CSNK1E,CNTNAP2,BRINP1,RUSC2,C2CD2L,SGSM2,MBNL2,MTSS1L,ZNF391,ZNF589,FGFR1,FYB1,SEPT9,SOX21,KPNA5,MAPT,MGAT3,ENPP2,RETREG1,PTPRB,PID1,KHDRBS2,SBF1,FRMPD1,ZNF667,SPATA7,ASTN2,TCF4,TMEM121,TIAM1,OSBP2,VIPR2" Drug 5424_DN Cefoperazone dihydrate; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "APLP1,PPFIA3,ATP6V0A1,CFLAR,CFAP410,ARHGEF2,FOXN3,B4GALT6,SLIT2,IQCK,NECTIN3,CRY2,CSNK1E,SIPA1L1,DBN1,JAKMIP2,BAIAP2,FAM49B,HNMT,IL6ST,MIA2,GIT1,NF1,PLXNB1,TMEM231,SBF1,BTBD7,ZSWIM8,ZBTB43,SS18,TTBK2,RPGRIP1L,TK2,PARD3,HIRA,KCNK12,NDRG4,GDPD5" Drug 2916_DN Letrozole [112809-51-5]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BRAP,ANK2,ZBTB10,CD86,ENTPD6,SOCS6,HOMER3,VCAN,C2CD2L,ATP2C1,GLYR1,PAXBP1,MX1,NF1,SETD4,OGG1,ENPP2,GPR85,PLCB2,STRN3,PILRA,SNRK,TMEM104,TMEM231,RXRA,MAPK12,PPM1E,FBXO11,ARHGEF40,KBTBD4,EXOC7,DMXL2,SYNE1,KAT6B,LAT2,NT5M,UBE3B,NLRP3" Drug 6176_UP chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASPHD1,BIN1,SEMA7A,APBB2,EPB41L5,BAIAP3,CACNA2D1,ASIC3,CHN1,CABP1,ARHGEF10,CNTNAP2,ARHGAP24,TMCC2,SNX29,MRNIP,RASGRP2,STX2,ANKMY1,OLFM1,FGFR1,FLNC,GNAL,GRM8,KCNJ5,KPNA5,NF1,NNAT,PDE4D,CEP41,TMEM231,SEMA6D,SH3BGR,PEX26,SEPT8,PHLDB1,TAL1,DNAH7" Drug 4597_DN Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BIN1,CDC14B,NRP2,SCAPER,CFAP410,CACNA1A,CBFA2T2,TPP1,RAB26,HOMER3,PPP6R2,RUSC2,EDIL3,GAD1,HLF,ITPKA,SCAMP5,MN1,GIT1,FA2H,POLG,GRAMD1C,CNNM2,RIPOR1,GAL3ST4,DZIP1,ANKRD6,LIMS2,ARHGEF40,ZNF334,ZNF667,ZHX3,DNAH7,CHST8,OSBP2,VGF,VIPR2,PCBP4" Drug 2230_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASIC1,C1QTNF3,LTBP4,BIN1,APBA2,ARRB1,MARK4,MTMR3,HAP1,CNOT8,TAOK2,SH2B1,CNNM1,BAIAP2,PDLIM5,DISC1,GLYR1,POLL,GPER1,CNTRL,GRIK5,GSN,HNMT,ITPKB,JAK2,STMN1,MAP4,TM6SF1,ADAM22,PALM,TCP11L1,SBF1,FBXO11,SNCA,KDM4C,ELOVL4,RPGRIP1L,TNS2" Drug 6661_DN Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ALK,AMPD3,APAF1,APC,ARRB2,SLC4A4,ALDH7A1,CBFA2T2,GIT2,RUSC2,EDIL3,ING4,COQ7,SEMA4D,TRMO,TRAF3IP2,SYNPO,MPP2,MX1,NF1,NFYA,POLG,MAPK7,ELOVL2,GTDC1,GSTCD,ZNF821,ASAP3,AMBRA1,PREX2,PPP4R3A,TMCC1,TBCEL,TIAM1,UBTF,VGF,SEMA3B,NAV3" Drug 6345_DN Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BRAP,BIN1,KCNAB2,VCAN,SLITRK5,ARMCX2,EGFR,EZH1,SCML2,CINP,GPD2,MAN1B1,FAM69A,ZNF862,SLC11A2,SETD4,PIK3R1,PID1,RAD51D,ROGDI,ZDHHC14,MAPK12,SH3BP2,EPN2,TTC17,SYT1,CABIN1,TNS1,LMF1,XRCC4,TRIM9,TFIP11,PCBP4,ST7,PHTF2,TIGD6,AAAS,RNF146" Drug 3547_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "EPB41L5,DDO,ATP1A3,BCL7A,CFAP410,CA4,SLIT2,FAM149A,MYRIP,VCAN,PDE4DIP,EGFR,OLFM1,KHDRBS3,DISC1,CNTRL,GRM8,IL6ST,MGAT3,NF1,NPTX1,NTRK2,PPARA,GDPD2,PTPRB,CRTAC1,KCTD17,RPS6KA2,PKNOX2,COA1,SNCA,SPTAN1,TBCEL,GPR161,TNS1,SLC30A3,KCNAB1,AP3B2" Drug 2495_DN Ethionamide [536-33-4]; Down 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "NDRG2,SYNJ2,MTMR2,CFAP410,HIP1R,CD86,PLAA,CRY2,ABCG1,AATK,CSF1R,CSNK1E,CNNM1,EIF5,EIF1,DLC1,CELF1,GALC,LILRB4,ATXN2L,TJAP1,P2RY1,STRN3,CNNM2,CNTLN,PTPRN2,GALNT10,FAM214B,SLC11A1,SEPT8,KANK1,SYN2,DNMBP,KIAA1107,CRTC1,PCBP4,UBE3B,ACTR3B" Drug 5813_UP Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASPHD1,C1QTNF1,CDC14B,KIF1A,CFLAR,CACNA1A,TAOK2,IQCK,ENTPD4,EDN1,IRAK4,STX2,FGFR1,BAIAP2,PRELID3A,ALDH1L1,GRM8,JAK2,KCNJ5,MYT1,PIK3R1,SNRK,PID1,EMID1,ASAP3,SLC14A1,TMCC1,KDM4C,TAL1,TCF4,TRIM2,PIK3R5,NPL,ZNF711,TFIP11,SEMA3B,PHTF2,DPF3" Drug 6067_DN Ricinine [524-40-3]; Down 200; 24.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "NDRG2,NME5,AK2,KCNAB2,MARK4,ARHGEF2,PPP6R2,DAPK3,RUSC2,DTNA,MBNL2,IRAK4,ING4,C3orf18,FAM198B,PRELID3A,ALDH1L1,USP19,GRB10,KCNF1,MAP4,MID1,GIT1,PLXNB1,MAPK7,RGS3,SBF1,SH3BP2,KDM4C,ARHGAP26,SS18,STX1A,PLCB1,MCF2L,TRIM2,ZNF34,SLC44A1,PHTF2" Drug 3269_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ABHD6,AP2A2,APBA2,APC,CASK,PLA2G4C,ATP6V0A1,NRP2,ST3GAL5,CBFA2T2,CLGN,LY86,RASSF2,RUSC2,LYPD1,DTNA,FGF12,STON1,INPP5B,KCNN1,MATK,MYT1,NECAB2,RAD51D,C1orf54,SH3BP2,CAMTA2,JMJD6,SMG6,SZT2,DOCK9,WBP2,FLRT2,VLDLR,XRCC4,ZBTB14,NT5M,KAT6A" Drug 2622_DN Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ALCAM,BCAS1,NCOA1,EIF4G3,CFAP410,PLEKHB1,VAX2,PDE4DIP,GIT2,DBT,EIF5,RGS17,EZH1,FHL1,DISC1,POLL,GNG4,BTN2A1,RNFT2,HNMT,MAP4,NFYA,NPR2,PDE4A,ZDHHC14,NEK11,RPS6KA2,ZNF821,TRA2B,SNCA,TSPYL2,ASTN2,MTCL1,TRIO,XRCC4,ZBTB14,EMSY,MPPE1" Drug 4740_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AK2,GAS7,BCAS1,ARHGDIG,SLC4A4,CBFA2T2,ARHGAP33,SOCS6,PLEKHB1,QKI,HOMER3,SLC4A8,CRY2,RIMS2,TBC1D5,JAKMIP2,MBNL2,HSD17B14,DLC1,AFF2,GALC,GLYR1,TDRKH,KITLG,RETREG1,LRP12,SAMD9,ZSCAN32,CEP97,RGS12,PREX2,PEX26,ZKSCAN3,PLCB1,KIAA0930,CABIN1,HIRA,LMF1" Drug 7359_UP Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASPHD1,AMH,APAF1,APBB2,CDK10,CDK13,MTMR3,CCNT1,AP4M1,QKI,HOMER3,SIPA1L1,TBC1D5,C2CD2L,OPTN,SRPK3,DLC1,ST3GAL6,FAM49B,SRCAP,SPACA9,GRM8,ATXN2L,ELOVL5,JAK2,ADAM22,NF1,PRODH,TMEM104,RGS12,FBXW7,SLC22A4,LIMCH1,TTBK2,PLCB1,WSCD1,SLC44A1,ST7" Drug 5450_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "NDRG2,APBB2,PDE8B,MARK4,SYNJ2,SCAPER,MTMR3,BAIAP3,CBFA2T2,ARHGAP33,ARHGEF6,SH2B1,NCOR1,PPP6R2,DAPK3,MBNL2,IQCG,MPP6,TRAF3IP2,GLYR1,MSL3,MUM1,ELOVL5,KPNA5,NF1,CNOT4,SLC11A2,SLC25A23,PLXNB1,LRP12,PPP5C,PTCH1,BTBD7,PLCB1,EXOC7,ZKSCAN5,GDPD5,SEMA3B" Drug 4387_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AMT,APC,APLP1,CNTN1,FAM169A,RCAN1,EGFR,ING4,ACSL4,DLC1,ALDH1L1,SRCAP,ARFIP1,RUNDC3A,GLYR1,GNG4,CNTRL,CACFD1,IL6R,KIT,NF1,CNOT4,LRP12,MAPK7,ELOVL2,C1orf54,ZNF821,LIMCH1,SPTAN1,TSPYL2,TROVE2,STX1A,DMXL2,PCDHA6,CABIN1,HIRA,FLRT2,EMSY" Drug 7540_UP semustine; Up 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AMH,BIN1,KCNAB2,CFLAR,BMP7,MTMR3,SGCE,ZMYM4,MAGI1,CLGN,STOML1,VAX2,IQCK,CREM,CSNK1E,GIT2,C3orf18,FECH,AFF2,DISC1,USP19,CRCP,BTN2A1,KCNQ3,LSS,ZNF862,RETREG1,PPP3CC,CCDC40,CARF,EXOC7,DMXL2,SZT2,TK2,ICAM5,TRIO,LMF1,ZNF45" Drug 4267_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADD2,SYT13,ZSCAN18,KIF1A,KSR1,CACNA1I,CFAP410,CACNA2D1,CALB2,KALRN,NCOR2,ARHGEF4,CDON,EDN1,EPHB1,ZNF549,DLC1,NSG1,TRAF3IP2,SEPT9,SRCAP,GFER,GNAO1,PRUNE2,LPAR4,MYT1,NNAT,NOVA2,LRRN3,KLHL11,PNMA8A,SLA,SS18,MCF2L,PCDHGB6,HIF3A,TK2,RIMBP2" Drug 920_UP 5-aza-2′-deoxycytidine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "APAF1,APC,CFLAR,LDLRAD4,SLC16A4,ARHGEF2,LRRFIP1,SRSF11,CLCN3,NRG2,ARHGEF4,RIMS2,HIPK3,SUGP2,MBNL2,EIF4G2,COQ7,MTSS1L,STX2,RRAGB,ST3GAL6,ERAP1,SEPT9,LPAR4,CNTRL,GRM8,MUM1,DHX35,KPNA5,NF1,PLTP,ELOVL2,KHDRBS2,SCN2B,SOX3,TROVE2,TRIO,ZNF45" Drug 5990_UP Thalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADORA2A,LTBP4,AMH,BIN1,SEMA7A,APAF1,KCNAB2,MTMR3,CA12,MTMR7,CNTFR,ING4,VPS13B,RASGRP2,MTSS1L,ERBB4,DLC1,HPCAL4,OGA,SIGLEC8,GLI2,POLL,GRM8,TJAP1,KCNN1,KIT,MYT1,NTRK3,MAPK7,SBF1,FAM214B,KANSL3,UHRF1BP1L,WSCD1,TCF4,DOCK9,FAM155A,ADAMTS9" Drug 6887_DN SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "LTBP4,BIN1,APBB2,ALDH7A1,CFLAR,ARHGEF1,TAOK2,CLCN3,SULT4A1,PDE4DIP,DMPK,MRNIP,DENND4A,FECH,MPP6,DISC1,HNMT,HSF2,TJAP1,LIG4,NF1,SLC11A2,STRN3,RNASEL,SEC14L1,AMBRA1,EPN2,RBM34,SEPT8,CEP68,VPS13A,TACC1,ANKRD12,HEY1,RPRM,VLDLR,GDPD5,PHTF2" Drug 2290_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADRA1D,APBA2,EPB41L5,APOC1,PLA2G4C,CA4,ARHGEF2,CACNA2D2,RCBTB2,CNOT8,AKAP7,GREB1,TBC1D5,DUSP9,HSD17B14,ZNF589,TPK1,TMEM8B,SPACA9,GRIK5,MAP4,MIA2,MYT1,NEK1,CNOT4,PLTP,ELOVL2,KCTD17,BTBD7,KIF13A,ZBTB43,CLSTN2,PLCB1,FBXW11,CABIN1,WIPF1,LAT2,SLC30A3" Drug 2907_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADD2,ADORA1,ADRA1D,MTUS1,APAF1,DNAH17,PTCH2,CAMK2G,LARGE1,CHRNA4,PICK1,ABCG1,DAPK1,MFAP3L,KLHL3,SPEG,FCGRT,NBEA,SRCAP,RUNDC3A,GRIK5,SCAMP5,MMP16,ADAM22,MYO6,NINJ2,SLC25A23,MTRF1L,PURG,EPB41L4B,PTPRN2,KLHL11,TCP11L1,GALNT10,IQSEC2,ATP10B,TNS1,RPRM" Drug 2520_DN Tetrandrine [518-34-3]; Down 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASIC1,NDRG2,ADRB2,TRMT9B,AMPD3,BIN1,AMT,APBB2,KIF1A,SIPA1L1,SPOCK3,RASGRP2,MTSS1L,FGFR1,EFCAB2,SEPT9,ARFIP1,LPAR4,GRM8,MAP4,MAPT,MYT1,ZCWPW1,MRAS,FRMPD1,BTBD7,SNCA,DMXL2,ZEB1,TNS2,THRA,TNS1,TRIO,FLRT2,XRCC4,SH3GLB2,FAM13C,ACTR3B" Drug 3642_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "KIAA1324,APOC1,MARK4,ATP1A3,ST3GAL5,GYG2,HIP1R,CHRNA4,CSF1,MAML1,HS3ST2,C3orf18,FLT1,PDLIM5,SRCAP,MSI1,ZNF862,CDK18,PFKFB2,PLTP,PLXNB1,PNMA3,CEP41,PTH1R,RNASEL,SCN8A,STUM,SH3BP2,HECW1,ZBTB43,POGZ,WSCD1,SZT2,FAM189A1,TPM2,UBE3A,LAT2,ZNF225" Drug 7492_UP semustine; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ARNTL,DNAH17,CBS,CBFA2T2,TPP1,STOML1,SH2B1,FEM1B,CDKL3,EZH1,ST3GAL6,FER,IQCG,TRMO,CINP,CGREF1,B4GALNT1,TDRKH,GRIK5,CACFD1,BTN2A1,SCIN,IL6R,KIFC3,LIG4,KCTD15,PRPH,PTPRD,TMEM231,HSPA4L,FAM214B,SNCA,KDM4C,HIRA,UBE2H,MAP3K12,PLSCR4,TIGD6" Drug 5608_UP Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "C1QTNF1,ADGRF5,SEMA6A,LTBP4,BCAS1,ADGRB1,ARHGEF1,LHX2,PICK1,WHRN,CSF1,IPCEF1,PHF14,EGR3,C3orf18,FHL1,HPCAL4,ADAM28,GNAO1,SPACA9,GRIK5,ATXN2L,JAK2,MAN2A2,KITLG,MX1,NOVA2,MTRF1L,CEP41,MAPK7,RET,RGS12,TCP11L1,SEMA6D,SCN8A,TAL1,PDIA2,DNALI1" Drug 338_UP "azathioprine, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BRAP,BIN1,KCNAB2,CDK10,ARNTL,PLA2G4C,ATP6V0A1,EDN1,ING4,ENO2,EPHB1,STX2,SEMA4D,TRMO,CAMKK2,PRELID3A,FYB1,ERAP1,GNAL,GSN,ATXN2L,ITPKB,KIFC3,L1CAM,PTOV1,NF1,PCBP3,SLC11A2,GPR173,PPP2R2B,ZCWPW1,EMID1,SH3BGR,ELMO2,TBL1X,PLPPR2,WIPF1,AAAS" Drug 3254_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "MTUS1,APC,CDC14B,ARRB1,NUMB,CFLAR,TPP1,QKI,COL4A5,SLC4A8,GREB1,LYPD1,DMPK,EGFR,KAT8,FGFR1,PDLIM5,ZNF44,SEPT9,SRCAP,TXNL4A,KCNMB4,GPD2,TJAP1,IPO5,SLC25A23,CNNM2,RGS12,SLC25A36,RPS6KA2,EPN2,POGZ,SS18,DIP2A,ANKRD12,KIAA0930,PARD3,HPS4" Drug 5564_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "FZD9,LDLRAD4,CFAP410,KYAT1,SULT4A1,LY86,NRG2,CSF1R,DAPK1,SPOCK2,ELN,GABRG2,SEPT9,ALDH1L1,GRIK5,C2orf72,MBP,MID1,AFDN,NOVA2,PLXNB1,PURG,PTCH1,ELOVL2,PTN,FRMPD1,SLC9A5,ZNF415,TSNAXIP1,SPP1,SYT5,WSCD1,ZEB1,PCDHGA10,SLC35G2,TRIM9,KCNAB1,HRASLS" Drug 221_UP 17-AAG; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BIN1,CDK10,MPDZ,KRIT1,ARHGAP33,CACNA2D2,SIPA1L1,HDAC4,DNAJB6,ENO2,CDKL3,BAIAP2,AGAP2,SRCAP,GPR37,RNFT2,ADAM22,NNAT,SETD4,PFKFB2,PLXNB1,TCP11L1,MAPK12,SUPT20H,HSPA4L,SH3BGR,FNDC3A,SLC12A4,IFT122,KDM4B,CLSTN2,ANKRD12,EXOC7,TRIM2,VIPR2,LMF1,MPPE1,FXR1" Drug 7540_DN semustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "RALGAPA1,ABR,ADCY6,CDK10,ARHGDIG,MARK4,ST3GAL5,CA12,UBE2L6,QKI,PDE4DIP,DZIP3,DBT,FBXL5,EIF5,EPB41L2,SRCAP,IRAK3,NFYA,MTRF1L,PKIA,PRODH,PRPH,SNRK,MAPK12,SH3BP2,EPN2,SLC22A4,RBM34,KDM4B,CLSTN2,PLCB1,IQCE,BHLHB9,R3HDM1,KAT6B,RPRM,KAT6A" Drug 2956_DN Torsemide [56211-40-6]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "CDC42BPA,APBB2,RIPK1,RCBTB2,EPS15L1,RAB28,ENTPD4,CST3,SLITRK5,DOCK4,DTNA,EIF5,ING4,COQ7,EZH1,FHL1,FLT1,ERAP1,GLYR1,PRRC2B,GSN,ICA1,ITGA7,MX1,STRN3,MINDY2,PPP3CC,PTPRO,SH3BP2,FAM214B,ARFGAP1,SPATA7,DMXL2,KAT6B,TNS1,HSPBP1,SPHK2,UBE3B" Drug 4572_DN Cyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "RALGAPA1,MTUS1,APC,CDK13,ARHGEF1,CBFA2T2,PLAA,TPP1,QKI,CDC42BPB,SLITRK5,TBC1D5,DBT,FEM1B,DENND4A,FECH,CAMKK2,INPP5K,MAP4,CNOT4,PDPK1,PRPH,RIPOR1,RPS6KA2,SAFB,SUPT20H,AMBRA1,PDZD2,KDM4C,ZBTB43,TROVE2,CEP68,KIAA1107,TPM2,VIPR2,LAT2,PHTF2,AAAS" Drug 5024_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "TRMT9B,GAS7,CDC14B,MARK4,ADAM23,SCAPER,GYG2,GREB1,RUSC2,DMPK,EDN1,EGR3,EZH1,GRM8,SHISAL1,JAK2,KCNJ5,MBD1,MEF2C,NF1,NPR2,MTRF1L,LRRN3,PRKAR1B,ZDHHC14,TCP11L1,EMID1,ASAP3,SYBU,COA1,KDM4B,TBCEL,SMG6,TNS1,LAT2,KCNK12,SEMA3B,SLC17A7" Drug 6163_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADORA2A,AMT,APAF1,SEMA4G,MARK4,BMP7,C5,CAPN3,ARHGAP33,EPS15L1,AKAP7,CPS1,SEC31B,ENTPD4,PPP1R16B,ARHGAP32,PLXNC1,STX2,GAA,SRCAP,GNG4,ATXN2L,TJAP1,MATK,NEFH,PMP22,PRKAB2,ZDHHC14,TCP11L1,SEC14L1,MRAS,MAPKBP1,KDM4B,DDN,DNMBP,XRCC4,NT5M,KAT6A" Drug 7264_DN Clorsulon [60200-06-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AK2,BIN1,NCOA1,MPDZ,CFLAR,MTMR3,HIP1R,PPP6R2,ZNF337,DBT,PARD6A,TNK2,STX2,F8,FGFR1,PDLIM5,FAM49B,ZNF44,TRAF3IP2,SESN1,ITPKB,MAPT,NPR2,CCSER2,MAPK3,SNRK,FAM102A,KBTBD4,CDK5RAP2,IFT122,RGL1,PHLDB1,EXOC7,KIAA0930,TNS2,BHLHB9,TSC2,OSBP2" Drug 4738_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ASIC1,ADORA1,SEMA6A,LTBP4,BEGAIN,SEMA7A,CDK13,AZGP1,CACNA1G,CD86,CNTNAP2,DCAF4,TMCC2,DTNA,ECM2,EDN1,EDNRA,AASS,MTSS1L,ZNF589,FHL1,GAD1,IFI16,KCNH2,KHK,MAPT,MEF2C,NTRK2,PLCD1,POU6F1,C1orf54,PNMA8A,RPS6KA2,ATP10B,SYT5,CRTC1,SLC17A7,ITM2C" Drug 3327_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ALCAM,APAF1,APBA2,FAM131A,CACNA1I,LDLRAD4,HAP1,TAOK2,ARHGAP24,EDNRA,HIPK3,EGR3,VPS13B,ZNF589,FGFR1,OGA,RUNDC3A,ADAMTS13,GRIK5,ICA1,C2orf72,JAK2,KCNN1,MMP17,MSR1,TREM2,LRP12,PPP2R2B,SAMD9,ZNF493,TRIM68,RET,CARF,RASA3,KDM4B,DMXL2,ZFP37,MKRN3" Drug 5092_DN Rimexolone [49697-38-3]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "STX16,ALDH7A1,HIP1R,KRIT1,CBFA2T2,RCBTB2,TAOK2,VCAN,DBT,MBNL2,STX2,ERCC2,DENND4A,ANKMY1,ACSL4,ANKFY1,EFCAB2,SPIN1,GPD2,RASSF8,SHISAL1,KCNN1,MITF,NDP,PLCD1,VPS13C,PID1,CSRNP3,SUPT20H,WDR37,EPN2,LIMS2,TROVE2,DIP2A,ARHGEF9,WSCD1,ZKSCAN5,HIRA" Drug 6259_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "BIN1,AMT,APC,CDC14B,BCL7A,CFLAR,GYG2,LDLRAD4,ZMYM4,QKI,CREM,LRIG1,SUGP2,MBNL2,VPS13B,FGFR1,BAIAP2,IQCG,BTN2A1,HNMT,TM6SF1,ADAM22,NF1,RETREG1,LRP12,MAPK7,SAMD9,WDR25,RGS4,FBXW7,PPP4R3A,PDZD2,FNBP1,UNC5B,CLASP2,CABIN1,VIPR2,KCNAB1" Drug 2311_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "LTBP4,SEMA7A,FAM131A,APOC1,CDK13,SCAPER,WASF1,RAB28,PDE4DIP,DZIP3,DAPK3,EGFR,TNK2,CGREF1,COPS8,CNTRL,GSTM5,MAP4K5,KCNN2,ZNF862,NTRK2,PALM,MBOAT7,PRKAR1B,VPS13C,TMEM104,AMBRA1,FBXO11,ANKRD6,SIRT2,ZKSCAN3,SPTAN1,EXOC7,TMEM121,TIAM1,TRIO,ZBTB14,EMSY" Drug 5440_UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADORA1,BIN1,APAF1,ATP1A3,CD86,SYNGR3,TPP1,SULT4A1,DMPK,DNAH9,TOM1,EYA1,OLFM1,FHL1,AFF2,PRELID3A,GATM,LPAR4,ICA1,MAP4,MYO7A,NPR2,TMOD2,PLTP,MTRF1L,PDZRN4,LRRN3,KCNIP1,SALL1,FAM214B,SLC11A1,OGDHL,NMNAT2,WSCD1,TRIM2,R3HDM1,TRIO,CLIP2" Drug 1831_UP Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "IL33,SOCS6,QKI,CPS1,DYNC1I1,E2F5,APH1A,ING4,AMOTL2,ARFIP1,GHR,CRCP,GLYR1,GUCY1B1,IFI16,IL6ST,INPP5B,JAK2,MATN3,CNNM2,PTCH1,KIF16B,CHD9,PEX26,ARHGAP26,SPTAN1,ELOVL4,VPS13A,COBL,KIAA0930,TRIM2,CLASP1,WBP2,HIRA,UPF3A,EMSY,EVI5,PDSS2" Drug 3358_DN Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ADORA2A,LTBP4,ALK,APBB2,APLP1,BCAS1,CDK10,MARK4,NCOA1,CLGN,RCBTB2,FOXN3,LY86,CNTN1,WHRN,VPS26C,CINP,TPK1,SRCAP,FERMT2,BTN2A1,RNFT2,DHX35,SMAD1,MID1,MMP16,PLCD1,PRKAR1B,GRAMD1C,ZSCAN32,SLC6A8,RBM34,ZHX3,ELOVL4,TNS1,VIPR2,XRCC4,KCNAB1" Drug 3194_DN Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "SEMA6A,LTBP4,DNAH17,ATP2A2,SCAPER,VAX2,CRY2,PDE4DIP,GREB1,ARHGEF4,KIAA0586,SGSM2,EDNRA,VPS13B,FGFR1,PRKAG2,SEMA4D,POMT1,MALT1,MSL3,POLL,LPAR4,MIA2,MSI1,NNAT,MBOAT7,WDR25,FBXW7,KIF13A,TMCC1,ZHX3,STX1A,TNS2,VGF,VIPR2,REEP1,EPM2A,RNF170" Drug 2071_DN Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AMT,APOC1,CDK10,CFLAR,WHRN,CSNK1E,VCAN,FAM169A,DBT,NR1D2,DMTF1,EDN1,SCARA3,INPP5K,SRCAP,ARFIP1,COPS8,GPER1,SLC2A6,HNMT,SLC11A2,OGG1,TMEM260,HSPA4L,CCDC88A,COA1,KDM4C,ZBTB43,PBLD,CAMTA2,JMJD6,UBTF,NT5M,NAV3,MPPE1,ST7,PHTF2,IFT88" Drug 3840_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "AMH,GAS7,ARRB1,SYNJ2,CNOT8,TAOK2,RAB28,SIPA1L1,RIMS2,DCAF8,DAPK3,DTNA,MBNL2,GLYR1,GPD2,MPP2,ADAM22,ZNF862,NEK1,NPR2,PLCD1,ZSCAN32,ZSCAN2,RPS6KA2,EMID1,ZNF821,ASAP3,FUZ,FNDC3A,CDK19,EXOC7,KIAA1107,FBXW11,KIAA0930,KAT6B,ZKSCAN5,VIPR2,PHTF2" Drug 3328_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.08E-04 1.00E+00 5.68E-03 6.39E-02 38 195 "ALCAM,PPFIA3,CDK10,PLA2G4C,ADAM15,CFLAR,SYNJ2,CA4,SPAG9,VAX2,CRY2,CTH,TM9SF4,DBT,MRNIP,STX2,VPS26C,RRAGB,ANKFY1,B4GALNT1,ZNF276,RAB30,PRRC2B,CACFD1,ELOVL5,LSS,OCRL,PLCD1,SLC25A23,PRKAR1B,PRODH,RPS6KA2,CDK19,CEP68,PLCB1,TMPO,VGF,REEP1" Drug CID000002833 colchine Stitch 6.10E-04 1.00E+00 5.70E-03 6.42E-02 65 383 "ACHE,INTS2,MAGEE2,CFLAR,DST,CA4,CALB2,CALM1,CCK,CHRNA4,ABCG2,CNTN1,COL4A5,COL9A1,COL9A3,COL11A2,VCAN,BOC,TUBD1,STX2,CD320,PTK2B,TUBB3,FGF1,FGF11,FGF12,FGF13,FGF14,DCTN2,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,TUBA8,GPT2,TNFAIP8L3,LAMA2,STMN1,MAP2,MAPT,NPY,CNTN3,ABCB1,PIK3C2A,PKD1,LAMA1,PTK2,PTPRN,PTPRN2,PTX3,FNDC3A,SNAP25,PDZD2,SPP1,DDN,SST,STX1A,TBL1X,ACTR6,TUBB2A,TUBB1,TUBA1A,WNK3,NLRP3" Drug ctd:D002330 Carmustine CTD 6.18E-04 1.00E+00 5.77E-03 6.50E-02 79 485 "ACTN1,ADRA1B,AGT,AMH,ANK2,KCNAB2,APC,VAT1L,ARNTL,ATP1A3,ADAM15,BMP7,BAIAP3,CALB2,PRC1,CDC25B,NGEF,COL9A1,CRYBB1,PITPNC1,ELMO1,ECM2,EDNRA,PHC2,SPEG,APC2,ETV1,FECH,BAIAP2,FOXF2,CGREF1,FYN,GALNT15,GP1BB,GPR37,ATXN2L,IGF1,KCND2,KCNH2,KIF5A,STMN1,MGAT3,SCAMP5,MSR1,NBL1,NFE2L2,NFIX,OGG1,PCDHGC3,PFKFB2,ABCB1,ZNF655,SEPT4,MAPK10,PRPH,MASP1,RORB,MEG3,STX1B,SCN8A,TNFRSF19,SHMT2,ST6GAL1,ST8SIA1,PKNOX2,SLC12A2,SLC14A1,ZC3H13,SYP,CUX2,ICAM5,NPL,SYNPO2,UGT8,VGF,VLDLR,WIPF1,ZNF189,SLC30A3" Drug CID000003007 amphetamine Stitch 6.20E-04 1.00E+00 5.79E-03 6.52E-02 51 284 "ABR,ADCY5,ADCY6,ADCY8,BRAP,ADORA2A,ADRA1D,ADRA1B,ADRB2,CACNA1B,CACNA2D1,CALM1,CAMK2A,CAMK2B,CAMK2G,CARS,CCK,CS,CSNK1E,DAPK3,DNM1L,MRO,ZMYND10,PPP1R1B,FOXO3,CAMKK2,GAD1,LOXL3,MCHR1,GPR37,GRIA2,GRIN2C,GRIN2D,GRM2,GRM8,MYLK2,PACRG,NPY,OPA1,OPRL1,PDPK1,PRKCB,MAPK3,KLK6,SIRT2,SNCA,SYN2,MLST8,ZEB1,RICTOR,SLC17A7" Drug CID000446755 P-NE Stitch 6.37E-04 1.00E+00 5.94E-03 6.69E-02 34 169 "ADORA1,ADORA2A,ADRB2,ARRB1,ARRB2,PDE8B,ALDH7A1,RIPK1,RGS9,CALM1,CBFA2T2,LRBA,CNGA3,CABP1,AKAP5,GIT2,ETV1,PPP1R1B,AKAP3,DISC1,GPD1,GPD2,MYLK2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PRKACB,PEG10,SSTR2,TBL1X" Drug CID000003446 gabapentin Stitch 6.37E-04 1.00E+00 5.94E-03 6.69E-02 34 169 "ASIC1,ADORA1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CACNA2D2,ASIC3,GRIN3A,GABRA3,GABRB3,GABRG1,GABRG2,GPT2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,ATXN2L,KCNH2,MEIS1,MEST,ABCB1,PKD1,PSAT1,RYR3,SCN7A,SLC6A11,TPCN2" Drug CID000004650 benzoquinone Stitch 6.46E-04 1.00E+00 6.02E-03 6.78E-02 40 209 "ACHE,APAF1,ATP2A2,ATP2B2,BCHE,CNR1,HDAC9,CHRDL1,DYNC1I1,ENO2,COQ7,ERBB2,HSPA12B,PPP1R1B,IP6K2,ATP2C1,PPARGC1A,TCERG1,PACSIN2,HP,HSF2,KCNH2,ASPRV1,OGG1,ABCB1,POLG,PPP5C,QDPR,GSTCD,FBXW7,ATXN7,FOXRED1,HSPA4L,SNCA,SYNE1,CYB561A3,ZMAT3,TLR4,PRTFDC1,JPH3" Drug 7537_UP CP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.51E-04 1.00E+00 6.06E-03 6.82E-02 37 189 "ASIC1,CDC42BPA,ADGRB2,NRP2,SCAPER,MYRF,CFAP410,WHRN,CRY2,CTH,PITPNC1,MRNIP,CDKL3,PTK2B,OGA,SRCAP,USP19,TXNL4A,HTATSF1,POLL,PRRC2B,FAM69A,CNOT4,SMOX,PRPH,CNNM2,KIF16B,FAM214B,ARHGAP26,DDN,PLCB1,SYT1,ASTN2,EXOC7,TCF4,SZT2,RNF146" Drug 836_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.51E-04 1.00E+00 6.06E-03 6.82E-02 37 189 "RALGAPA1,OSBPL1A,APC,EPB41L5,PPFIA3,CDC14B,SCARB1,TAOK2,FAM189A2,CREM,CRY2,DBT,OPTN,GRB10,LIG4,OXTR,MORC4,ZNF821,HSPA4L,SH3BGR,PPM1E,ASAP3,ZKSCAN3,SMARCC2,LIMCH1,ZBTB43,TSPYL2,DIP2A,PHLDB1,JMJD6,EXOC7,PARD3,ZKSCAN5,VLDLR,ZNF189,ST7,FXR1" Drug 3770_DN Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.51E-04 1.00E+00 6.06E-03 6.82E-02 37 189 "ASIC1,NME5,APC,ARHGAP22,LHX2,PLAA,SMARCAL1,SIPA1L1,SLITRK5,DCAF4,ARMCX2,RHOBTB1,SGSM2,FEM1B,EIF5,FGF1,DCTN2,GUCY1A1,ITPKB,ZNF862,SETD4,RETREG1,SAMD9,WDR25,ZSCAN32,SH3TC2,RPS6KA2,MAP6D1,ST6GAL1,FAM214B,GLT8D1,ASTN2,KIAA1107,RPGRIP1L,TNS1,ZNF32,HPS4" Drug 6717_DN Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.51E-04 1.00E+00 6.06E-03 6.82E-02 37 189 "MTUS1,PDE8B,SYNJ2,MYRF,RAB28,ENTPD4,CNTNAP2,TBC1D5,EXOG,FCF1,SPEG,ETV1,ZNF589,FGFR1,IQCG,ANKFY1,GLYR1,HNMT,IL6ST,KPNA5,NDP,CNOT4,TMEM231,FAM184A,TRAPPC13,SAFB,MAPK12,LIMCH1,NXT2,ZEB1,DNAH7,SSBP2,UBTF,XRCC4,MPPE1,UBE3B,PHTF2" Drug CID000123788 Super-Bond Stitch 6.51E-04 1.00E+00 6.06E-03 6.82E-02 8 19 "ABR,KDM5D,CNOT8,ARHGAP32,F8,L1CAM,RAD51D,SALL1" Drug CID000590836 k143 Stitch 6.51E-04 1.00E+00 6.06E-03 6.82E-02 8 19 "APC,NCOA1,CALB1,DMPK,POLK,INPP5K,PPARA,TP53BP2" Drug CID000010889 cetyl palmitate Stitch 6.51E-04 1.00E+00 6.06E-03 6.82E-02 8 19 "ABHD6,BLM,CBS,CHGB,GAL3ST1,ENO2,KIT,NPY" Drug CID005270634 library 2 Stitch 6.51E-04 1.00E+00 6.06E-03 6.82E-02 8 19 "AP2A1,AMPH,SYNJ1,CLTC,ARHGEF6,DNM1,DNM1L,OCRL" Drug CID000002369 betaxolol Stitch 6.51E-04 1.00E+00 6.06E-03 6.83E-02 14 48 "ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CA4,CA12,CACNA2D1,TBPL1,EDN1,MAPK3,MAPK4,MAPK7" Drug 5612_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.67E-04 1.00E+00 6.14E-03 6.92E-02 35 176 "APBB2,MARK4,BCL7A,CA12,CAMK2G,CRLF1,PDE4DIP,MFAP3L,SACS,HIPK3,EGR3,RACK1,FECH,FGF12,CGREF1,GPD2,KHK,LSS,MAP4,MBNL1,KITLG,MMP16,NACA,PDCD2,MBOAT7,ZHX3,CDK19,ASTN2,KIAA0930,ZMAT3,CABIN1,METTL3,REEP1,SLC38A1,NETO2" Drug 3804_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADCY6,AMPH,PRX,ARSE,CDK13,BMP7,STOML1,COL9A3,CSF1R,DTNB,FRY,EZH1,ABCA8,AGAP2,PDLIM5,ATXN2L,TJAP1,ITGA7,CDH20,KCNF1,KCNJ5,KCNN1,SMAD1,MBP,MGAT3,AFDN,NF1,P2RX7,WDR25,KHDRBS2,RFX2,RGS12,SEMA6D,SH3BP2,SLA,DOP1A,PHF24,JPH3" Drug 5569_DN 2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ABR,NDRG2,C1QTNF3,ALCAM,LTBP4,APOC1,SYNJ2,CBFA2T2,CNOT8,CRY2,RUBCN,DOCK4,C2CD2L,BAIAP2,TPK1,OGA,SEPT9,MALT1,CACFD1,RASSF8,ZNF862,NF1,RETREG1,SLC25A23,CNNM2,NEK11,RPS6KA2,SBF1,FAM214B,COA1,SMARCC2,ZHX3,ASTN2,CDK20,PLPPR2,REEP1,EMSY,SEMA3B" Drug 4359_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,AMT,APBB2,APLP1,FAM131A,STX16,BAIAP3,FOXN3,STOML1,CNTFR,CSF1,ERCC2,NCALD,ANKMY1,AGAP2,CINP,POLL,MAP4,MAPT,TM6SF1,MMP16,NLE1,RASA3,ASAP3,LIMCH1,TSNAXIP1,ZBTB43,CLSTN2,PLCB1,KIAA0930,ZEB1,SZT2,ZNF34,TK2,HIRA,VGF,ITM2C,KAT6A" Drug 1432_DN Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; HL60; HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "KCNAB2,APC,N4BP2L1,SYNJ2,PLAA,SOCS5,APPL1,CTH,DENND4A,ACSL4,SEC23B,SMC2,FAM49B,TRAF3IP2,SPIN1,MAP4K5,IRAK3,IFI16,KTN1,AFF1,MYO5A,NFE2L2,NFYA,NUCB2,SNX10,RETREG1,PLCD1,GSTCD,CLIP1,ATXN7,HSPA4L,FBXO11,RBM26,SPART,ZNF302,STAU1,UBE3A,EVI5" Drug 5343_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SRPX,APBA2,APC,ARRB1,CDK13,CFLAR,CA12,SCARB1,FAM189A2,CSF1,ARHGEF10,SPOCK2,MFAP3L,CDON,OPTN,DLC1,KAT8,ZNF589,SEMA4D,TXNL4A,GLYR1,SPACA9,INPP5B,NFYA,NLE1,NKAIN1,RGS12,SEC14L1,ERC1,SPART,TROVE2,VPS13A,EXOC7,WSCD1,TRIM2,ZNF34,FAM155A,GDPD5" Drug 2033_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADORA1,APBA2,APC,MARK4,RASL11B,SLC4A4,N4BP2L1,BCL7A,CFLAR,MTMR3,MTMR2,CRY2,B3GAT3,ING4,FGFR1,OGA,SRCAP,GDF9,AHDC1,MCHR1,SLC2A6,TJAP1,KCNB1,KCNH2,SCAMP5,MMP17,MYT1,NFYA,NOVA1,OCRL,PDE1C,GALNT10,ELMO2,TSNAXIP1,TBL1X,OBSL1,WBP2,CHST5" Drug 6695_UP Felodipine [72509-76-3]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADD2,NME5,ADGRF5,LTBP4,PPFIA4,APAF1,APC,CDK13,ADGRB2,CBS,CHRNA4,TAOK2,HAPLN1,MBNL2,PLXNC1,ST3GAL6,FGFR1,GRM8,ITPKA,PACRG,KITLG,NTRK2,PCDH9,ENPP2,MINDY2,ELOVL2,ZSCAN32,RPS6KA2,SLC11A1,KIF13A,PDZRN3,TROVE2,CRTC1,HIRA,ZNF24,SLC17A7,EPM2A,GAN" Drug 6313_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADORA1,TRMT9B,KIF1A,SYNJ2,CACNA1G,LDLRAD4,NDST3,LHX2,RIMS2,PLXNC1,EIF4G2,MRNIP,LRRC17,FGFR1,USP19,ZNF276,GLI2,CNTRL,SCIN,INPP5B,KCNF1,KHK,NF1,PDE4A,PFKFB2,SNRK,PTCH1,ACSS3,MRAS,FRMPD1,SSTR2,TACR1,TAL1,KLHL4,NSD1,PCDHA5,LAT2,KCNAB1" Drug 3637_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,ALCAM,DOC2A,AMPD3,BIN1,PPP4R4,SYNJ1,BAIAP3,CA12,CACNA1A,FOXN3,LHX2,SH2B1,PDE4DIP,MFAP3L,ZNF589,FOXF2,PDLIM5,B4GALNT1,GCNT2,GSN,MMP16,NPTX2,PCDH9,LRP12,PRKAR1B,RELN,ZDHHC14,RET,ZFHX4,KCNIP1,KDM4B,DOK5,DOCK9,THRA,TNS1,ZFP37,ITM2C" Drug 2784_UP Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,ALCAM,AMPH,CDC42BPA,PPFIA3,ATP2A2,SGCE,CALB1,CACNA2D2,RCBTB2,TAOK2,NECTIN3,DCAF4,C2CD2L,PARD6A,MAMLD1,TNK2,HSD17B14,F5,BAIAP2,DLL3,GCNT2,GSN,GSTM5,ITPKB,KCNQ3,GIT1,PLCD1,NECAB2,RELN,ZSCAN2,C1orf54,RPS6KA2,ZNF821,SNCA,TRIM2,TK2,SPHK2" Drug 1002_DN 2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AK2,CDK10,MARK4,ATP6V0A1,CFLAR,SYNJ2,GYG2,CCNT1,TAOK2,HOMER3,NCOR1,PARD6A,MED12,DTNA,CELSR3,PCOLCE2,ACSL4,SYT17,INPP5K,SRCAP,MAP4,MAPT,NEK1,OGG1,OXTR,PLEC,POLG,TMEM104,PEX26,CDK5RAP2,TROVE2,IQCE,SIN3B,KIAA0930,HIRA,EIF4ENIF1,URM1,ST7" Drug 2196_DN Ethotoin [86-35-1]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "N4BP2L1,RIPK1,CFAP410,CACNA1A,CAPN3,SCARB1,HOMER3,CSF1,PDE4DIP,ZNF337,TBC1D5,DAPK3,DBN1,RCAN1,DTNA,FRY,EIF1,GPHN,ERCC2,VPS26C,TXNL4A,MAP4K5,IL6R,LIG4,LSS,AFF1,N6AMT1,CCSER2,ZDHHC14,C12orf49,FNDC3A,NUBPL,THSD1,ZC4H2,SS18,NXT2,TSN,MPPE1" Drug 1312_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "BRAP,CDC42BPA,APAF1,APBB2,ARHGEF7,CAMK2G,AP4M1,ARHGAP33,TMEM184B,SIPA1L1,ZNF337,MAML1,SPATA2,PLXNC1,ERCC2,ANKMY1,FGFR1,CRCP,MUM1,IDH3A,MAP4,MEF2C,MIA2,OCRL,FAM184A,RGS3,FAM214B,KDM4B,STX1A,ARHGEF9,EXOC7,IQCE,NSD1,ZKSCAN5,PLPPR2,LAT2,NPDC1,ACTR3B" Drug 6781_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AGT,KCNAB2,RGS20,ADAM23,CFLAR,CA4,HAP1,PDE4DIP,RIMS2,MBNL2,ENO2,STX2,FHL1,PDLIM5,NSG1,GRIK5,ICA1,MAP2,NPTX1,PLCB2,LRP12,ZSCAN2,TCP11L1,CNKSR2,FAM214B,ARHGEF9,DMXL2,CRTC1,DICER1,CHST8,TK2,TMPO,R3HDM1,CHST5,TRO,RPRM,LAT2,EPM2A" Drug 4409_DN Alcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,APBA2,PDE8B,KIF1A,ST3GAL5,CA4,CA12,CAMK2G,LHX2,BAG4,SIPA1L1,RIMS2,SPOCK2,ZNF804A,DMPK,ERCC2,BAIAP2,FHL1,FAM49B,GCNT2,KIT,KPNA5,ZNF862,RETREG1,MAPK7,C1orf54,RGS12,SBF1,SH3BP2,EPN2,UNC5B,PLCB1,WSCD1,DICER1,HIRA,SPHK2,SLC17A7,KAT6A" Drug 5563_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,BIN1,ARHGDIG,CRLF1,RCBTB2,SLIT2,TPP1,FAM189A2,PPP6R2,HIPK3,KAT8,FGFR1,BAIAP2,FHL1,PRELID3A,RAB30,POLL,RASSF8,KCNH2,MID1,NF1,NFYA,SLC11A2,SETD4,RETREG1,POLG,PRPH,SAMD9,TMEM231,FBXW7,SBF1,PHLDB1,MCF2L,WSCD1,CRTC1,CDK20,REEP1,MPPE1" Drug 2335_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG3,NDRG2,ALK,MARK4,ALDH7A1,CFLAR,SYNJ2,C5,CSF1,SIPA1L1,KIAA0753,CNNM1,MRNIP,CDKL3,ZNF589,DISC1,TJAP1,LSS,MAPT,GIT1,NELL2,NINJ2,NNAT,NPR2,P2RX7,MTRF1L,FBXW7,SEMA6D,GALNT10,FERMT1,BTBD7,SNCA,TBL1X,NSD1,CRTC1,VGF,SPHK2,ZBTB38" Drug 6288_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APAF1,PPFIA3,KALRN,LHX2,NRXN3,CNTFR,PDE4DIP,MAML1,BRINP1,RCAN1,COQ7,RRAGB,ABCA8,ST3GAL6,DENND2A,ERAP1,RUNDC3A,GRIK5,HNMT,IL6ST,KCNB1,MT1M,CNOT4,NPR2,ENPP2,PTCH1,PTPRE,RGS12,GSTCD,SH3BP2,SLA,CCDC88A,SLC11A1,SNCA,ZHX3,SP4,ZBTB14,KCNAB1" Drug 4294_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "PKP4,PDE8B,N4BP2L1,ATP6V0A1,ADAM23,BMP7,MTMR3,CACNA2D1,HAP1,SLC16A4,CNR1,SPOCK3,FCF1,SEMA3D,ETV1,ERAP1,ALDH1L1,GDF9,GUCY1B1,SCIN,KCNJ5,MBP,NF1,NNAT,PCBP3,LRP12,ZSCAN2,CCDC40,ZCWPW1,RGS4,CPEB3,SLC12A4,RBM26,TCF4,DMXL2,TMPO,LAT2,KCNAB1" Drug 4204_DN Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADRA1D,TRMT9B,CDC42BPA,APOC1,KIF1A,LHX2,RGS6,CNTNAP2,C2CD2L,SPOCK3,SGSM2,EIF4G2,MFSD10,MTSS1L,ZNF589,SCARA3,FYB1,GRM8,SOX21,ZNF862,RETREG1,NLE1,FSD1,PPARA,MAPK7,PTPRB,KHDRBS2,RGS4,SH3BP2,FRMPD1,AMBRA1,KANSL3,KIAA0930,CABIN1,XRCC4,NT5M,KCNAB1,MPPE1" Drug 1155_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ABHD6,MTUS1,AGT,APBB2,ARNTL,ST3GAL5,SLC16A4,SLITRK5,DOCK4,DAPK1,RUSC2,DTNA,MBNL2,EXTL2,F5,SEPT9,INPP5K,ALDH1L1,RAB40B,GPD2,LILRA2,ITGA7,SCAMP5,CCSER2,PTN,PTPRN2,SATB1,ANKRD6,DBNDD2,ZC4H2,TCF4,SLC44A1,TPM1,TRPS1,NPDC1,ZNF32,PHTF2,ACTR3B" Drug 3482_DN Pyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,ADRA1D,BIN1,APC,PPFIA3,ARNTL,CDK13,STX16,ST3GAL5,SCAPER,C5,CFAP410,SOCS6,PLEKHB1,LHX2,ABI3BP,DBN1,MFAP3L,SLC12A6,HIPK3,EIF4G2,FGFR1,ZNF276,LPAR4,HNMT,ICA1,INPP5B,RETREG1,MBOAT7,MINDY2,PPP5C,MAPK10,NEK11,ZNF821,SLC22A4,LIMCH1,TSNAXIP1,MPPE1" Drug 5236_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "LTBP4,APBB2,DNAH17,CFAP410,HAP1,ARHGEF1,NECTIN3,ENTPD4,CRY2,CSF1,RIMS2,CDON,MBNL2,FAM198B,FHL1,FUT9,GLYR1,RAB30,GPER1,GRIK5,KCNN2,MBD1,ADAM22,MX1,ZNF862,PFKFB2,RETREG2,ZFHX4,ASAP3,SLC2A5,SNCA,PLCB1,TACC1,BEX4,PIK3R5,CHST5,ZKSCAN5,LAT2" Drug 5574_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "C1QTNF3,CDK10,SGCE,CAMK2G,KRIT1,CRLF1,QKI,HOMER3,AKAP7,CREM,PPP6R2,TBC1D5,CNNM1,APH1A,RRAGB,POLL,RASSF8,ICA1,RBPJ,KCNH2,TM6SF1,NACA,STRN3,TMEM104,GTDC1,GSTCD,ROBO1,NEK11,FERMT1,FBXO11,BTBD7,USP33,ZBTB43,TBCEL,CRTC1,DICER1,ZIC1,SEMA3B" Drug 7357_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APOC1,CDK13,MTMR2,ZMYM4,BAG4,DCAF8,DBT,LYPD1,DTNA,FGFR1,FHL1,GALC,COPS8,GLYR1,GPD2,DHX35,KCNH2,LIG4,MBD1,KITLG,STRN3,PPP5C,GSTCD,SAFB,FNDC3A,ZBTB43,ITPRID2,SS18,NXT2,TACC1,FBXW11,SZT2,CABIN1,XRCC4,NDRG4,KCNAB1,UBE3B,ACTR3B" Drug 6014_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "CDC42BPA,ATP6V0A1,CREM,ENTPD4,MED12,CDON,ANKMY1,FGF12,FGFR1,SEMA4D,ERAP1,DISC1,INPP5K,GLYR1,RAB30,GRM8,HNMT,IL6R,MAP4,ZNF862,PCDH9,PRKAR1B,PTPRE,SBF1,ASAP3,AMBRA1,PEX26,FAM214B,SOX3,ZHX3,LHPP,PLCB1,ASTN2,IQCE,CABIN1,PLPPR2,KCNAB1,AAAS" Drug 2501_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SEMA7A,APC,RASL11B,CA12,THSD7A,CDO1,SLIT2,STOML1,SULT4A1,CNTN1,ABI3BP,CREM,DCAF4,EXOG,DTNA,HIPK3,FAM13A,MBNL2,ZNF549,AFF2,SEPT9,NTRK2,SETD4,PDE4D,PLCL1,PRKAR1B,MARCH1,PPM1E,SNAP25,SPART,ZEB1,RPGRIP1L,TK2,PARD3,TPM1,VIPR2,KLC2,SLC17A7" Drug 2962_DN Spaglumic acid [4910-46-7]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,CASK,ARRB1,SLC4A4,ATP6V0A1,BACH1,SYNJ2,SGCE,CAMK2G,SLC16A4,CLGN,TPP1,C2CD2,CSF1,DBN1,RUSC2,DTNA,FAM13A,ING4,CDKL3,ERAP1,DISC1,SRCAP,ADAM28,MX1,ZNF862,PTK2,PTPRO,RIPOR1,ZCWPW1,RET,PPM1E,AMBRA1,BTBD7,MAPKBP1,SMUG1,TRPS1,NT5M" Drug 4956_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADCY6,AP2A2,AK2,BCL7A,MTMR2,CBR1,SYNGR3,VAX2,QKI,PDE4DIP,PPP6R2,JAKMIP2,DTNA,IRAK4,RGS17,ENO2,JAK2,MBD1,MEIS1,NEK1,PLCD1,PLEC,POLG,MAPK3,NEK11,ELMO2,BTBD7,SMARCA4,ZBTB43,STX1A,ASTN2,EXOC7,TRIM2,TMPO,KAT6B,TRIO,LMF1,FTSJ1" Drug 4124_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ALCAM,AMPD3,GAS7,DNAH17,CAMK2B,HIP1R,ARHGEF1,CNTFR,WHRN,SH2B1,NCOR2,AATK,VCAN,RIMS2,DMPK,CDON,SRPK3,NRN1,DLC1,GSTM5,ATXN2L,MYT1,PDE1C,RETREG1,MAPK7,PTH1R,ZSCAN2,KHDRBS2,CRTAC1,SCN8A,STUM,ARHGAP26,POGZ,KIAA1107,HIF3A,TK2,PIK3R5,TRIO" Drug 2221_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SEMA6A,SRPX,BACH1,CFLAR,SGCE,BAIAP3,USP2,SEPT7,CDH2,VCAN,GREB1,RIMS2,EDNRA,MBNL2,PLXNC1,NCALD,F5,FGF13,FGFR1,PRELID3A,FYB1,MSL3,ITPKA,KCNH2,MAN2A2,MMP16,PFKFB2,PLCD1,ASAP3,SLC9A5,SLC11A1,ATP10B,PLCB1,SMG6,WSCD1,NT5M,SLC17A7,KAT6A" Drug 2317_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NME5,CFLAR,GYG2,CLGN,QKI,CNTN1,AKAP7,CABP1,CNTNAP2,RIMS2,DCAF4,DUSP9,EDNRA,HIPK3,EGR3,VPS13B,RCAN2,LRRC17,RASGRP2,ERCC2,SPEG,APC2,ZNF589,FGFR1,FYB1,ITPKA,L1CAM,SMAD1,MGAT3,ADAM22,CLDN11,RELN,CCDC40,SH3GL3,ASAP3,CXXC4,WSCD1,RPGRIP1L" Drug 3271_DN Brompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APC,APOC1,PPFIA3,CDC14B,CFLAR,SCAPER,GYG2,SLC4A8,PPP6R2,NR1D2,FEM1B,EGFR,IRAK4,FECH,FGFR1,FAM49B,TXNL4A,GSN,MPP2,SLC11A2,PPP3CC,RXRA,SBF1,ZNF821,SGK1,SH3BP2,ZHX3,SS18,KANK1,ANKRD12,MTCL1,EXOC7,TIAM1,CABIN1,ZNF189,HPS4,SEMA3B,EPM2A" Drug 3571_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "KCNAB2,EPB41L5,SEMA4G,RGS9,SYNJ1,BAIAP3,THSD7A,USP2,CD86,CBFA2T2,FOXN3,ASIC3,HOMER3,ARHGEF6,CRY2,DAPK1,DTNA,DTNB,PLXNC1,KAT8,KHDRBS3,ELOVL5,AFDN,GIT1,NF1,NFYA,ENPP2,PLEC,FRMPD1,ASAP3,PKNOX2,ARHGAP26,DDN,ATP10B,CLSTN2,PLCB1,TNS1,GDPD5" Drug 5615_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,NME5,ALCAM,AMT,FAM131A,NUMB,CFLAR,SGCE,ARHGEF2,PLEKHB1,TPP1,QKI,HOMER3,SIPA1L1,DOCK4,RRAGB,EZH1,FER,FGFR1,MALT1,GLYR1,CACFD1,INPP1,INPP5B,KITLG,NPTX1,LRP12,PPP3CC,PPP5C,NEK11,SYBU,SLC22A4,TROVE2,CLSTN2,TTBK2,PLCB1,SIK3,SLC17A7" Drug 6027_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "BEGAIN,BIN1,APLP1,ATP2B2,KALRN,TAOK2,TPP1,WHRN,AKAP5,MYRIP,DTNB,EGFR,ING4,EPHB1,ZNF589,FYB1,GFER,GLI2,GRM8,KCNB1,KCNJ5,KCNN1,AFDN,NOVA2,NTRK2,PPP5C,GRAMD1C,RGS4,PNMA8A,PKNOX2,SLC11A1,HIF3A,TLR4,TPM1,CA14,FAM155A,FLRT2,CLIP2" Drug 4675_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "MTUS1,AGT,ALDH7A1,CACNA1G,CAST,SYNGR3,CRLF1,FOXN3,TAOK2,AKAP7,NRG2,SH2B1,AATK,DTNA,EDNRA,CNNM1,MRNIP,RGS17,ZNF44,TRAF3IP2,IFI16,TM6SF1,NF1,PIK3R1,ZSCAN32,PTPRB,GSTCD,ATXN7,FRMPD1,TSNAXIP1,SOX15,HIRA,LMF1,WIPF1,TFIP11,KCNAB1,PHTF2,TIGD6" Drug 6021_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "LTBP4,DOC2A,BIN1,PPP4R4,SYNJ2,CA4,AATK,EDN3,COQ7,OLFM1,BAIAP2,GPER1,KCNN1,KCNN2,NFYA,CDK18,RETREG1,GRAMD1C,KHDRBS2,EMID1,KCNIP1,SCN2B,SEC14L1,SH3BP2,SYBU,PKNOX2,LIMCH1,CDK19,ATP10B,PHLDB1,PLCB1,SYT5,GPR161,R3HDM1,KCNK12,SPHK2,ITM2C,MARCH8" Drug 3448_DN Dienestrol [84-17-3]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APBB2,MPDZ,CFLAR,CFAP410,B4GALT6,BAG4,CLOCK,FAM169A,TBC1D5,TOM1,TNK2,EZH1,FAM49B,ARFIP1,GHR,FERMT2,GPD2,GPR37,MIA2,KITLG,GIT1,ADAM22,NPR2,TMEM104,PTCH1,NEK11,FERMT1,FBXO11,ITPRID2,SS18,TACC1,TMPO,TSN,SSBP2,PLPPR2,LMF1,MPPE1,PHTF2" Drug 4808_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "RALGAPA1,C1QTNF1,LTBP4,APBA2,KCNAB2,APLP1,CFLAR,BAIAP3,CA4,CACNA1A,ENTPD2,ARHGEF2,CNTNAP2,GREB1,TMCC2,PIPOX,FER,AFF2,EFCAB2,HTATSF1,POLL,GNAL,LPAR4,OCRL,PALM,PTH1R,ZFHX4,FRMPD1,SLC6A8,SMARCD3,RBM26,THSD1,EXOC7,IQCE,WSCD1,CRTC1,ZNF24,KCNAB1" Drug 2104_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,SEMA4G,ALDH7A1,KIF1A,SCAPER,SCARB1,CPS1,PLEKHA1,EZH1,FGF1,FGFR1,FAM49B,SEPT9,LYVE1,TDRKH,CNTRL,ICA1,JAK2,GIT1,CNOT4,NOVA2,PDE4D,POLG,TMEM231,GAL3ST4,SLA,SLC2A5,CCDC88A,ZKSCAN3,MYH15,SYNE1,CHST8,TPM1,SSBP2,HIRA,UBTF,LMF1,NT5M" Drug 4776_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ABHD6,BCL7A,CFLAR,CA12,ARHGAP33,AKAP12,GPRASP1,ZNF337,DAPK3,TUBD1,ANKMY1,DLC1,ERAP1,TXNL4A,ITPKB,JAK2,KIF2A,IPO5,MAP4,NCAM2,NF1,OCRL,PIK3R1,POLG,PRODH,CEP97,RXRA,ZNF331,FAM192A,TACC1,DICER1,ZNF34,TPM1,VGF,LMF1,XRCC4,HPS4,MPPE1" Drug 2530_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "C1QTNF3,APAF1,PRX,PDE8B,MYRF,CBFA2T2,STOML1,CNTFR,CREM,CRY2,SIPA1L1,PPP1R16B,RUBCN,DOCK4,MFAP3L,GSDME,EDN1,FGFR3,FLT1,GNG4,KCNJ5,MEF2C,AFDN,SAMD14,MYO6,SLC11A2,P2RY1,DUSP26,MAPK10,RIPOR1,CARF,SCN2B,SEC14L1,SLC11A1,SP2,UBE3A,FZD3,SENP7" Drug 3992_DN Phenacetin [62-44-2]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APC,MARK4,SLC4A4,SLC25A14,SEPT7,FOXN3,SLC4A8,CREM,AATK,SLITRK5,DZIP3,PPP6R2,DCAF4,ZNF337,MFSD10,COQ7,STX2,ZNF589,FGF1,B4GALNT1,MIA2,MN1,PPARA,GRAMD1C,SH3TC2,MSANTD2,FBXW7,RXRA,FBXO11,ST6GAL1,FAM214B,ARHGEF40,RBM34,ZBTB43,ARC,SSBP2,HPS4,NAV3" Drug 1182_DN "estradiol, USP; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,CDK10,NCOA1,NUMB,N4BP2L1,CFLAR,SLC25A14,CD86,TPP1,ENTPD4,VCAN,DPH1,RCAN1,FCF1,ING4,TXNL4A,LILRB4,LILRA2,ICA1,KIF2A,LIG4,LSS,MITF,NF1,SLC11A2,OCRL,PIK3R1,PLCB2,CEP97,TRIM68,TCP11L1,GALNT10,IQCE,TCF4,KAT6B,UBTF,FLRT2,MAP3K12" Drug 3206_DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,AK2,APOC1,CDK13,SCAPER,CFAP410,SPAG9,USP2,SCARB1,SOCS6,QKI,HOMER3,WHRN,PDE4DIP,DAPK3,MFAP3L,TOM1,FCF1,MALT1,POLL,GRM8,KCNH2,MATK,MIA2,KITLG,PDE4A,PLTP,PTCH1,CEP97,RGS12,NXT2,ARHGEF9,EXOC7,TMPO,CDK20,TRIO,ZKSCAN5,EVI5" Drug 3830_DN Solasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADRA1D,APAF1,APBB2,GAS7,ARHGDIG,MARK4,SLC4A4,SCAPER,SYNGR3,ASIC3,SH2B1,RIMS2,SLC12A6,EZH1,KAT8,GFER,POLL,KCNH2,ADAM22,RETREG1,SNRK,ZSCAN2,ZMAT4,RGS3,EMID1,SH3BP2,FAM214B,SNCA,DOP1A,KDM4C,ARHGAP26,STX1A,EXOC7,CRTC1,CHST8,TNS1,VIPR2,LAT2" Drug 5819_UP Trifluridine [70-00-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADGRF5,SLC4A4,CFLAR,CFAP410,CAMK2B,CHRNA4,LHX2,ABCG2,PCYT1B,ABCG1,PDE4DIP,DZIP3,GIT2,DTNA,FEM1B,MRNIP,TUBD1,STX2,SCML2,FLT1,ERGIC3,SPACA9,GRIK5,NF1,PCDH9,PIK3R1,ASAP3,FNDC3A,TMCC1,ZBTB43,PLCB1,SZT2,VGF,KCNK12,MPPE1,PLSCR4,HRASLS,RNF170" Drug 203_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,BIN1,ASPA,SYNJ2,FUBP1,SCARB1,STOML1,CRMP1,SRPK3,ERCC2,BAIAP2,PDLIM5,ATP2C1,RUNDC3A,SYNPO,AGFG1,ICA1,MYT1,NTRK2,CLDN11,PPM1B,PRKAR1B,TTC13,FERMT1,ABLIM3,SLA,FAM214B,PKNOX2,SNAP25,SNCA,FAIM2,SPTB,TSPYL2,ST5,PHLDB1,PLCB1,PARD3,MPPE1" Drug 7369_UP Kawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADCY6,CDC42BPA,ATP2B2,TAOK2,STOML1,HOMER3,USP6NL,SPOCK3,EIF4G2,ETV1,FGFR1,PDLIM5,ERAP1,ZNF276,SHISAL1,TJAP1,IL12A,FAM69A,KITLG,TAGLN3,NDP,CLDN11,PPARA,WDR25,PTCH1,PTPN13,SH3TC2,ROBO1,ZKSCAN3,TMCC1,CDK19,ASTN2,KLHL4,DOCK9,GPR161,R3HDM1,TNS1,ZKSCAN5" Drug 1821_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "MTUS1,PKP4,PPFIA3,CASK,SYNJ2,CBFA2T2,CHN2,QKI,DZIP3,DBT,KLHL3,FCF1,SUGP2,EZH1,FGF1,TRAF3IP2,ARFIP1,HNMT,HSF2,IFI16,JAK2,SH3TC2,NCBP3,SLC4A3,CCDC88A,KDM4B,ZHX3,PEG10,ARHGAP26,IQSEC2,CEP68,JMJD6,SYNE2,TRIM2,ZNF34,TMPO,WNT7A,RNF146" Drug 5111_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "OSBPL1A,TRMT9B,BIN1,CDC14B,DNAH17,KSR1,KALRN,CBS,HOMER3,ARHGEF10,CSNK1E,PHF14,DTNA,CELSR3,TENM1,SPEG,APC2,NRN1,SPACA9,GRIK5,SYNPO,LYRM9,PALM,PDE4D,MBOAT7,SNRK,ZSCAN2,RASGRF1,HSPA4L,OGDHL,ARHGAP26,ZBTB43,TROVE2,SMG6,PCDHGB6,CDK20,SH3GLB2,TFIP11" Drug 1930_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AQP6,PDE4DIP,SPATA2,KLHL3,EDN1,ING4,EZH1,GFER,DIDO1,SHISAL1,KIF5A,GIT1,NELL2,NFYA,CDK18,PPP2R2B,CEP41,MAPK7,PTN,RET,MAPK12,ATXN2,SH3BP2,ARHGEF40,ZKSCAN3,ZBTB43,WSCD1,TNS2,PLPPR2,VIPR2,LAT2,WRN,ZBTB14,ZNF24,REEP1,GDPD5,AAAS,DPF3" Drug 5061_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APC,SLC4A4,CBFA2T2,ARHGEF2,SOCS6,HOMER3,CNTNAP2,HDAC9,ARHGAP24,TOM1,EDIL3,HIPK3,RGS17,SPEG,ETV1,ZNF589,TRAF3IP2,GAD1,GUCY1B1,INPP5B,SCAMP5,PLXNB1,BCAS3,CNTLN,FAT4,ROGDI,RXRA,MAPK12,DZIP1,PEX26,SMARCC2,TMCC1,SS18,NXT2,ELOVL4,TK2,OSBP2,LMF1" Drug 4166_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASPHD1,NRP2,ARHGEF7,CFAP410,CA4,ARHGEF1,CBFA2T2,ARHGEF2,FOXN3,SNCAIP,PDE4DIP,PHF14,SCML2,ZNF589,KHDRBS3,SEPT9,GLYR1,POLL,GPER1,GSN,RNFT2,KCNN1,AFF1,ADAM22,MX1,SERPINI1,PLEC,KCNIP1,DHX30,COA1,SNAP25,ZHX3,THSD1,PLCB1,PARD3,TRPM2,REEP1,PDSS2" Drug 1494_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,C1QTNF3,CDC42BPA,ARHGDIG,CFLAR,RAB29,BAIAP3,LARGE1,QKI,MFAP3L,HS3ST2,DTNA,MBNL2,LRRC17,PTK2B,OGA,ALDH1L1,SRCAP,PRRC2B,GRB10,DHX35,KIFC3,MAP4,MBD1,MMP16,NACA,SEPT4,POLG,POU6F1,PRODH,PTPRH,RNASEL,DOK5,VPS13A,EXOC7,CHST8,THRA,ITM2C" Drug 4148_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADRA1D,SEMA4G,CDK13,RIPK1,CA4,B4GALT6,DCAF4,DAPK3,RCAN1,DTNA,HIPK3,SCML2,ZNF589,FGFR1,SEPT9,POLL,MAPT,NF1,NFYA,CNOT4,SETD4,CDK18,PLCD1,MINDY2,PRKAR1B,WDR25,PTN,TCP11L1,SH3BP2,SLC9A5,CXXC4,COA1,PDZRN3,PLCB1,SZT2,PARD3,TRPM2,EMSY" Drug 5000_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADRA1D,LTBP4,APLP1,ADAM23,CAMK2B,CRLF1,ASIC3,SULT4A1,NRG2,SH2B1,ELN,VPS13B,EPHB1,DLC1,FGFR3,SCARA3,GAD1,SIGLEC8,SRCAP,SESN1,GNAO1,GPD1,ICA1,KCNH2,MIA2,ADAM22,NF1,PFKFB4,MBOAT7,RPS6KA2,FRMPD1,ATP10B,WSCD1,ZEB1,PCDHA5,TNS1,METTL3,KCNK12" Drug 2394_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "RALGAPA1,EPB41L5,AZGP1,RUNX1T1,CREM,CRMP1,NCOR1,DCAF4,DGKG,EXOG,RASGRP2,MTSS1L,PIPOX,RRAGB,FHL1,SCARA3,ADAMTS13,ICA1,KIT,NEK1,NPY,NOVA2,NPR2,PCDH9,PDE1C,PLCD1,POU6F1,PRKAR1B,DCHS2,CNNM2,RASGRF1,KCNIP1,ZHX3,SPTAN1,ARHGEF9,IQCE,ZNF34,FLRT2" Drug 6101_UP Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,BIN1,APC,APLP1,RUNX1T1,ARHGEF10,GREB1,ARHGEF4,HS3ST2,HEYL,SRPK3,HSD17B14,IGSF6,FHL1,SIGLEC8,PRUNE2,LPAR4,MGAT3,MID1,AFDN,ZNF862,NF1,NOVA2,PAX6,PGAM2,RETREG1,SAMD9,EMID1,PKNOX2,SLC9A5,SLC11A1,ZNF415,IZUMO4,ARHGAP26,ARC,TNS2,TRO,CA14" Drug 7297_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "FAM131A,KYAT1,RCBTB2,LHX2,ENTPD4,CTH,FAM131B,LYPD1,DYNC1I1,TUBD1,FGF13,CINP,SEPT9,GCNT2,SRCAP,CRCP,CNTRL,CLASRP,MAP4K5,HNMT,IL6ST,JAK2,SETD4,PLCD1,SMIM7,MAPK12,FAM214B,BTBD7,SLC22A4,SMARCD3,CDK19,ELOVL4,HIRA,SH3GLB2,UPF3A,EVI5,MPPE1,ST7" Drug 2551_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NUMB,SYNJ2,CACNA1A,HIP1R,CD86,SCARB1,HOMER3,IQCK,CPS1,CSF1R,KIAA0753,RUSC2,NR1D2,CDON,MTSS1L,F8,EFCAB2,PDLIM5,ERAP1,INPP5K,COPS8,LILRA2,SLC2A6,NCKAP1L,IFI16,MEF2C,SLC11A2,ENPP2,KCTD15,PLCB2,DEF8,TMEM231,CEP97,FBXW7,SEC14L1,ARHGEF40,DMXL2,LMF1" Drug 5669_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SYN3,AMPH,APBA2,ADGRB1,CFAP410,CALB2,CAMK2A,NRXN3,STOML1,NCOR2,CSF1,VCAN,PDE4DIP,SPOCK3,DMD,TENM1,ETV1,ANKMY1,ZNF589,FYB1,NEU3,GRM8,ICA1,TJAP1,LAMA2,ADAM11,NCF2,NF1,PCDHGC3,GRAMD1C,PTPRB,PTPRD,CEP97,GAL3ST4,SALL1,ZFP2,EPN2,EPM2A" Drug 3936_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NME5,SEMA6A,KCNAB2,GAS7,APLP1,CDC14B,PLA2G4C,ATP2A2,NECTIN3,CPS1,CSF1,CSF1R,DMPK,CDON,SLC12A6,EDN1,VPS13B,FHL1,IQCG,DISC1,JAK2,KIF5A,MAP4,NF1,PFKFB2,SERPINI1,RETREG1,STRN3,RPS6KA2,SEMA6D,SBF1,SH3BP2,FAM214B,MAPKBP1,IQCE,SATB2,VIPR2,EMSY" Drug 1546_UP Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,ADORA1,LTBP4,BEGAIN,CDK10,SEMA4G,SLC4A4,CA12,CACNA1A,CALB2,CACNA2D2,CNTFR,IQCK,SH2B1,TMCC2,TMEM35A,GNAO1,CACFD1,KCNF1,LAMA2,MBP,MMP16,GIT1,DUSP26,PPARA,PPP5C,PTN,PTPRN,PLPPR3,RXRA,SH3BP2,LIMS2,FAM214B,SLC11A1,SYN2,CRTC1,DNAH7,VGF" Drug 5742_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADORA1,AGT,SEMA7A,ADAM23,GYG2,PLEKHB1,CREM,CRMP1,HEPH,EXOG,ING4,ELN,OLFM1,AGAP2,LYVE1,GSTM5,ELOVL5,ICA1,SHISAL1,ITGA7,MYCN,NRCAM,PIK3R1,PPP5C,ENOX1,EMID1,FRMPD1,CNKSR2,ZSWIM8,LHPP,JMJD6,MCF2L,TBCEL,TCF4,TK2,ICAM5,TNS1,PIK3R5" Drug 2627_DN Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AK2,CDC42BPA,ARHGDIG,ADAM15,BCL7A,MTMR2,FAM189A2,VAX2,QKI,IQCK,DBT,FBXL5,DTNA,FCF1,TNK2,MRNIP,EZH1,FECH,FHL1,MSL3,RNFT2,AGFG1,MATK,NF1,NFYA,PLEC,PTCH1,SUPT20H,EPN2,ELMO2,SOX3,NXT2,PDLIM2,IQCE,TMPO,LMF1,XRCC4,MPPE1" Drug 3475_UP Cromolyn disodium salt [15826-37-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "LTBP4,APBB2,PPP4R4,CFLAR,CBFA2T2,B4GALT6,ABCG1,CSNK1E,PHF14,GREB1,ARHGEF4,CDON,HIPK3,VPS26C,FGFR1,GPER1,INPP5B,JAK2,KCNF1,KCNN1,NF1,PLXNB1,LRP12,MBOAT7,MAPK7,RPS6KA2,TRAPPC13,SEMA6D,ANKRD6,TMCC1,ZC3H13,SS18,TBL1X,KIAA0930,AP4E1,SLC44A1,TRIO,XRCC4" Drug 6782_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "RALGAPA1,ADORA2A,AGT,ALCAM,AMPD3,APBB2,ATP2A2,ATP2B2,SGCE,LDLRAD4,SEC14L5,BRINP1,RUSC2,EDN3,F5,FLNC,ZNF44,GFER,MALT1,ITPKB,KCNJ5,LAMA2,MBD1,MSR1,ZNF862,FXYD1,PTN,C1orf54,ZNF493,TCP11L1,ASAP3,SLC11A1,CXXC4,ARHGAP26,PLCB1,SYT5,LAT2,KCNK12" Drug 7181_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AP2A2,BIN1,KIF1A,SCAPER,FOXN3,CLOCK,CSNK1E,DCTN1,SGSM2,DMPK,MED12,MAMLD1,SEZ6L2,ERBB2,GPD2,AGBL5,MAN2A2,NF1,PLEC,MBOAT7,PRKAR1B,AMBRA1,ABLIM3,PDZRN3,SOX3,SPATA7,ZHX3,CEP68,ARHGEF9,PDLIM2,TNS2,KAT6B,CABIN1,TSC2,RPRM,LMF1,PHTF2,ACTR3B" Drug 918_UP ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADORA1,AP2A2,SPARCL1,ARRB1,CFLAR,ARHGEF2,CHRNA4,LHX2,VAX2,ARHGEF4,RIMS2,HDAC4,MFAP3L,DTNA,EDNRA,CNNM1,MBNL2,ERCC2,ST3GAL6,FGFR1,FGFR3,STON1,SLC2A6,IRAK3,HNMT,LMO2,KITLG,NLE1,RNASEL,SCN2B,TSNAXIP1,CAMTA2,ASTN2,TNS2,THRA,TRIO,RPRM,NLRP3" Drug 2248_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SEMA6A,CDC42BPA,APOC1,PLA2G4C,MARK4,CACNA1I,CAMK2B,PLEKHB1,CNOT8,SLIT2,ARHGEF6,AKAP7,CSF1,CSF1R,MFAP3L,CNNM1,EIF4G2,ZNF589,FHL1,SRCAP,GNG4,CNTRL,GSTM5,INPP1,MAP4,MPP2,ADAM22,ZSCAN2,C1orf54,CNKSR2,PEX26,ST5,PLCB1,WSCD1,TRIO,VIPR2,SEMA3B,TIGD6" Drug 2496_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ABHD6,MTUS1,BIN1,FAM131A,APOC1,CDK10,BACH1,SYNJ2,TAOK2,ABCG1,RUBCN,ZNF337,DGKG,FAM13A,PLXNC1,EIF5,TUBD1,F5,PDLIM5,USP19,POLL,TJAP1,GIT1,OGG1,GPR85,ZNF821,GALNT10,EPN2,BTBD7,ADGRL3,TCF4,ICAM5,R3HDM1,VIPR2,CLIP2,XRCC4,ZNF225,AAAS" Drug 4807_UP Nystatine [1400-61-9]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADCY6,ADORA1,BEGAIN,AMH,APOC1,MARK4,SLC2A11,CFAP410,CBFA2T2,DAPK3,EDN1,RASGRP2,F5,REEP2,DLC1,KAT8,KHDRBS3,KCNJ5,LSS,AFDN,PALM,RETREG1,PLTP,FBXW7,ZFP2,SLC6A8,ST5,PHLDB1,SYT5,SMG6,RIMBP2,TRIO,UGT8,OSBP2,WIPF1,MKRN3,NT5M,JPH3" Drug 1168_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "CDC42BPA,PKP4,GAS7,CDK10,ARRB1,ZSCAN18,NCOA1,ZMYM4,SULT4A1,CNTFR,ARHGEF10,PDE4DIP,DAPK3,B3GAT3,KIAA0753,PARD6A,DTNA,ANKRD46,RASGRP2,NEU3,AHDC1,GLYR1,KCNQ3,MAPT,CCSER2,PTK2,TRIM68,SEC14L1,SUPT20H,PREX2,SLC9A5,SNAP25,DBNDD2,SPTAN1,SS18,CBX5,PARD3,PHTF2" Drug 500_DN copper(II) sulfate pentahydrate; Down 200; 100uM; ssMCF7; HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "OGT,BCAS1,ATP6V0A1,RGS11,DDX46,DRP2,DTNA,MBNL2,PLEKHA1,FGFR1,BAIAP2,FLNC,POMT1,RUNDC3A,GPER1,GRIK5,PTPRT,GSN,SOX21,MARK1,MBD1,MYO7A,NF1,RETREG2,MBOAT7,EMID1,RASA3,PEX26,SNCA,KDM4B,LMO3,SSTR2,ELOVL4,STX1A,EXOC7,GPR161,PARD3,PLPPR2" Drug 4484_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "BMP7,FUBP1,BAIAP3,CFAP410,TAOK2,RAB33A,STOML1,HOMER3,PCYT1B,HAPLN1,ARHGEF10,PDE4DIP,SPOCK3,EXOG,DOCK2,DTNA,NCALD,ETV1,PIPOX,LILRB4,ITGA7,KCNH2,NPY,OPRL1,PPP2R2B,PRKAR1B,KCNIP1,FBXO11,SLA,SLC6A11,SLC11A1,BEX4,PIK3R5,VAV1,WIPF1,SPHK2,KCNAB1,AP3B2" Drug 2847_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,AK2,ALCAM,BIN1,APBB2,MARK4,CFLAR,KYAT1,MAGI1,LHX2,NECTIN3,ARHGEF4,TMCC2,EXOG,TSPAN5,SEMA4D,CAMKK2,ZNF44,HLF,ELOVL5,IL6ST,KCNH2,KHK,MITF,ADAM22,ZNF862,NNAT,ZSCAN32,ZNF493,SLC25A36,ZNF821,SNCA,SAMSN1,THSD1,SS18,DMXL2,AP4E1,HIRA" Drug 5833_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ABR,AMT,APC,APOC1,SLC4A4,CFLAR,HAP1,ARHGEF2,ASIC3,CNOT8,NRXN3,QKI,VCAN,CHRDL1,ANKMY1,SCML2,ICA1,KIFC3,MIA2,GIT1,TAGLN3,MX1,PPP5C,ELOVL2,PID1,TCP11L1,NCBP3,ZFP30,ASAP3,SLC2A5,TMCC1,ARHGAP26,CEP68,PCDHA5,ZNF711,REEP1,ZNF225,SEMA3B" Drug 4402_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "C1QTNF1,LTBP4,DNAH17,CACNA1I,CFAP410,KALRN,HIP1R,RHBDL1,TPP1,AATK,AASS,TNK2,IGSF6,PIPOX,CORO2B,FGF1,HPCAL4,GPR162,ADAM28,JAK2,MAP2,MAPT,MEF2C,MMP16,MMP17,MN1,NOVA1,ZFHX4,SCN8A,SLC8A1,ARHGEF40,SNAP25,ZC4H2,FAM189A1,TRO,TRPM2,UBE3A,FAM13C" Drug 6372_UP 3-nitropropionic acid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "PKP4,GAS7,BCAS1,SLC4A4,SLC2A11,BAIAP3,STOML1,SULT4A1,SLITRK5,LYPD1,DTNB,PDLIM5,FYB1,DISC1,GFER,LILRA2,TAGLN3,ZNF862,DUSP26,PLCB2,LRRN3,PRKAR1B,SAMD9,ACSS3,RNASE1,SALL1,ZNF821,SMARCD3,ZNF415,KDM4B,DDN,TROVE2,SYT1,TNS1,TPM1,VGF,VIPR2,XRCC4" Drug 6708_DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "RALGAPA1,TRMT9B,PDE8B,SLC4A4,STX16,FOXN3,QKI,CNTNAP2,RCAN1,FCF1,COQ7,ETV1,CINP,OGA,GPD2,INPP5B,KPNA5,NDP,NEK1,NFYA,CLDN11,PDE4D,PLXNB1,TMEM231,RPS6KA2,ASAP3,PPP4R3A,SPTAN1,POGZ,TCF4,DNAH7,GPR161,THRA,TMPO,RUNDC3B,HIRA,EPM2A,PHTF2" Drug 6315_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG3,CDC42BPA,ARRB2,KSR1,NFS1,CREM,ARHGEF4,PPP6R2,DTNA,EGFR,ANKMY1,CGREF1,DLL3,ERAP1,TXNL4A,GLYR1,BTN2A1,SYNPO,MAPT,MYO6,MAPK7,PID1,GAL3ST4,RPS6KA2,SBF1,FAM102A,IFT122,TMCC1,TSPYL2,SAMSN1,ELOVL4,ARHGEF9,BHLHB9,TSC2,PLPPR2,ZNF45,MAP3K12,PCBP4" Drug 2531_DN Butamben [94-25-7]; Down 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,ADRA1D,BIN1,DNAH17,CFLAR,CACNA1A,CAMK2G,PLAA,HOMER3,SH2B1,PPP1R16B,PLXNC1,MTSS1L,F5,ST3GAL6,FCGRT,FHL1,FYB1,GRM8,MAP4,ZNF862,NF1,PDE4B,ENPP2,NLE1,ZCWPW1,KHDRBS2,FRMPD1,BTBD7,TSNAXIP1,UNC5B,IQSEC2,TCF4,DMXL2,THRA,REEP1,FAM13C,ST7" Drug 2790_UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,OSBPL1A,KCNAB2,SCAPER,CACNA1I,CBLN1,CBFA2T2,RCBTB2,AKAP7,VCAN,HEPH,MBNL2,HSD17B14,ZNF589,FGFR1,GCNT2,GNAL,GPER1,HLF,ICA1,MATN3,SLC25A23,PRKCB,GRAMD1C,C1orf54,CLIP1,ASAP3,LIMCH1,KIF13A,ARC,DICER1,TK2,FAM155A,UBE3A,FLRT2,WIPF1,ADAMTS9,KAT6A" Drug 5760_DN Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "AK2,ALDH7A1,ADAM23,ARHGEF2,MAGI1,ASIC3,ARHGAP22,CRY2,PDE4DIP,CNTNAP2,DRP2,AASS,EIF4G2,MRNIP,COQ7,LRRC17,FGFR1,SCARA3,OGA,FYN,SEPT9,ZNF276,TDRKH,DHX35,MAP4,MAPT,ADAM22,NDP,CNOT4,NLE1,KCTD17,PLCB1,ASTN2,METTL3,HIRA,WIPF1,NT5M,EVI5" Drug 2843_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,NDRG2,APBB2,APC,CDC14B,ATP2A2,SLC2A11,PROM1,BMP7,CAMK2B,SYNGR3,NECTIN3,CREM,SH2B1,DMPK,EGFR,STX2,FGFR1,BAIAP2,SEMA4D,EFCAB2,IL6ST,KCNN2,KCNQ3,MMP17,NF1,NPTX2,OGG1,CNNM2,RPS6KA2,SNCA,SOX3,THSD1,TRIO,FAM155A,LAT2,ITM2C,KAT6A" Drug 2288_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ASIC1,ABHD6,AMT,CDC42BPA,APBA2,CFLAR,CA12,RUNX1T1,ARHGAP33,RCBTB2,CNTN1,BAG4,SH2B1,MAML1,MFAP3L,IQCG,SRCAP,GLYR1,TDRKH,GRIK5,ICA1,ADAM22,NF1,ZCWPW1,ZNF821,SH3BP2,RCOR3,VPS13A,FBXW11,TBL1X,DOCK9,PCDHA6,TK2,PARD3,ZBTB14,ZNF24,SLC30A3,PHTF2" Drug 4720_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "RALGAPA1,NME5,LTBP4,HAP1,CAMK2G,RUNX1T1,KRIT1,CRLF1,QKI,ENTPD4,CRMP1,GREB1,HDAC9,MAML1,GIT2,NCALD,GALC,GLYR1,CACFD1,IL6ST,KCNH2,MAP2,ADAM22,NTRK2,SERPINI1,PLCD1,MTRF1L,LRRN3,SH3BP2,AMBRA1,FBXO11,ZC3H13,SYN2,TBL1X,PCDHGA10,OBSL1,PCDHA6,HIRA" Drug 2966_DN Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "APBB2,CASK,SLC4A4,EIF4G3,CAMK2G,SLC16A4,CD86,RAB28,DZIP3,DOCK4,HDAC4,RUSC2,MBNL2,EGR3,FLT1,POMT1,ATP2C1,CGREF1,ERAP1,INPP5K,STON1,ITGAM,MAP4,MX1,PDE4D,SMIM7,PPP3CC,PTK2,FAM192A,SBF1,SGK1,FBXO11,SP2,ARHGAP26,DNMBP,AP4E1,TRPS1,ZNF32" Drug 1346_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NDRG2,CDC42BPA,CDK10,ATP2A2,BCL7A,C5,CAMK2G,NFS1,SCARB1,QKI,BAG4,CPS1,GIT2,DTNA,TOM1,PTK2B,ST3GAL6,FGFR1,EFCAB2,ERAP1,TXNL4A,GLYR1,KCNMB4,NFYA,NPR2,PFKFB4,PIK3R1,CCSER2,APTX,SBF1,DHX30,BTBD7,ARFGAP1,KDM4B,PLCB1,EXOC7,TBL1X,CHST8" Drug 4699_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "NME5,ATP1A3,ADAM15,MPDZ,MTMR2,RUNX1T1,QKI,RIMS2,GIT2,DBT,PARD6A,RASGRP2,NCALD,RRAGB,FGF12,FGFR1,FHL1,GALC,GLYR1,GRIK5,GSN,GSTM5,KITLG,MID1,MSI1,STRN3,NKAIN1,PNMA8A,TCP11L1,ZKSCAN3,UNC5B,SYN2,ZNF34,SSBP2,UCHL1,OSBP2,ZNF74,RNF146" Drug 4063_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ATP2A2,KIF1A,WHRN,CRMP1,ARHGEF10,DAPK3,PLPPR4,MBNL2,EIF4G1,IRAK4,FGFR1,ANKFY1,PDLIM5,FERMT2,SHISAL1,MAP4,MBD1,MEF2C,NPR2,P2RY1,PDE1C,PLXNB1,WDR25,ZSCAN2,PREX2,PPP4R3A,CCDC88A,ZNF415,TROVE2,TBL1X,ZEB1,TRIM2,R3HDM1,UGT8,VGF,LAT2,NT5M,GAN" Drug 2125_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "ADCY6,ADD1,ADGRF5,AMPD2,FAM131A,CDC14B,SEMA4G,ST3GAL5,MYRF,EPS15L1,SPATA2,CNNM1,IRAK4,FGF1,BTN2A1,IL6ST,KIF2A,IPO5,PIK3R1,SLC25A23,MAPK7,CNNM2,SAMD9,ZNF671,SH3BGR,SH3BP2,ZKSCAN3,SMARCA4,CAMTA2,COBL,EXOC7,TCF4,SATB2,ZEB1,CABIN1,HIRA,XRCC4,AAAS" Drug 3031_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.73E-04 1.00E+00 6.14E-03 6.92E-02 38 196 "SPARCL1,BMP7,KALRN,CHRNA4,SUSD5,RIMS2,SEC14L5,EGFR,PLEKHA1,FGFR3,BAIAP2,GABRG2,GAD1,GALC,B4GALNT1,SIGLEC8,ADAM28,RUNDC3A,PRUNE2,CACFD1,KCNN1,ADAM22,MYH3,NPY,PDE1C,FSD1,PSD,PTPN13,PTPRN2,TCP11L1,MAP6D1,PKNOX2,IZUMO4,UNC5B,SPTB,TBCEL,CHST8,AP4E1" Drug CID000002303 Bay K 8644 Stitch 6.75E-04 1.00E+00 6.16E-03 6.93E-02 31 150 "ADCY5,ADCY6,ADCY8,AGT,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,RGN,LRBA,CACNA2D2,DMPK,EDN1,EDN3,ATP2C1,BVES,MAP4K5,NF1,NPY,PKD1,PRKACB,PRKCB,QDPR,RYR3,SST,TPCN2" Drug CID000002482 butamben Stitch 6.79E-04 1.00E+00 6.19E-03 6.97E-02 7 15 "CACNA1I,CACNA1A,CACNA1B,ACOT8,KCND1,KCND2,L1CAM" Drug 1709_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.95E-04 1.00E+00 6.34E-03 7.14E-02 36 183 "BCL7A,CFLAR,C5,TBC1D5,NR1D2,DTNA,FCF1,ZNF589,FER,B4GALNT1,SEPT9,CRCP,SPIN1,IL6ST,MAP4,MITF,GIT1,MYO6,PIK3R1,STRN3,PRKAB2,TMEM104,TMEM260,SLC25A36,RPS6KA2,ZNF331,MAPKBP1,TMCC1,KDM4B,CEP68,TBL1X,DICER1,TMPO,ZBTB38,ST7,FXR1" Drug 5677_UP Bisacodyl [603-50-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.95E-04 1.00E+00 6.34E-03 7.14E-02 36 183 "CLK4,AP2A2,N4BP2L1,RGS11,FHL5,CPS1,SEC14L5,HS3ST2,EDN1,MBNL2,RASL12,KHDRBS3,FYB1,GNAL,BTN2A1,TJAP1,INPP5B,MATN3,NEFM,CNOT4,OGG1,MTRF1L,PTPRN2,FAT4,RFX2,PNMA8A,ZNF821,SH3GL3,SLC11A1,ATF7IP,HECW1,PARD3,ZKSCAN5,DNALI1,SEMA3B,JPH3" Drug 7088_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.95E-04 1.00E+00 6.34E-03 7.14E-02 36 183 "APBB2,IL33,CBFA2T2,RCBTB2,RAB28,ABI3BP,HAPLN1,PDE4DIP,CTH,DYNC1I1,RCAN1,APH1A,IRAK4,EPB41L2,ETV1,SPIN1,HTATSF1,GPR37,MAP4,PIK3R1,PLEC,BCAS3,PTCH1,RPS6KA2,ZFP30,PEX26,CDK19,PDLIM2,TRIM2,SYNE1,KAT6B,METTL3,SSBP2,HIRA,ZBTB38,MPPE1" Drug CID000017011 Depixol Stitch 7.08E-04 1.00E+00 6.45E-03 7.27E-02 11 33 "ADCY5,ADCY6,ADCY8,ZMYND10,GRIK4,GRIK5,GRIN2C,GRIN2D,KITLG,PDCD2,ABCB1" Drug 1167_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.11E-04 1.00E+00 6.47E-03 7.29E-02 34 170 "APBB2,ARNTL,NCOA1,CFLAR,CD86,CREM,SIPA1L1,PPP1R16B,SV2B,EDNRB,FAM13A,MBNL2,FHL1,ANKFY1,AHDC1,LILRA2,MUM1,IL6ST,PDE4B,PDE4D,PMP22,MBOAT7,PRKAB2,PRKACB,TRIM68,TCP11L1,HSPA4L,PEX26,SPTAN1,EXOC7,DMXL2,TNS2,FLRT2,ZBTB38" Drug CID000009308 muscarine Stitch 7.11E-04 1.00E+00 6.48E-03 7.29E-02 30 144 "ACHE,ADCY5,ADCY6,ADCY8,SLC24A4,BCHE,CACNA1B,CACNA2D1,CHRNA4,PLCXD3,DMPK,INPP5K,KCNMB4,PLCD4,KCNJ5,KCNK3,NPY,P2RY1,PDE1C,PDE1B,PLCB2,PLCD1,PRKCB,ENOX1,SLC8A1,SST,PLCB1,TACR1,ALG1,PLD4" Drug CID000011060 23 B Stitch 7.13E-04 1.00E+00 6.49E-03 7.31E-02 12 38 "MTUS1,SEMA6A,CDK13,VCAN,BOC,EIF1,NSG1,NF1,TCEA1,SYNE1,TIMP4,TSC1" Drug CID000001727 4-AP Stitch 7.21E-04 1.00E+00 6.55E-03 7.38E-02 47 258 "ACHE,ADORA1,ADORA2A,PHF12,KCNAB2,ATP1A3,CACNA1A,CACNA1B,CACNA2D1,CALB2,KCNAB3,ASIC3,EDN1,EPB41,HSPA12B,GABRG1,GABRG2,KCNMB4,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GUCY1B1,KCNB1,KCND1,KCND2,KCNF1,KCNH2,KCNJ5,KCNK3,KCNN1,KCNN2,KCNN3,KCNQ3,NPR2,PRKCB,KCNIP3,HSPA4L,SYN1,SYN2,SYP,UBTF,KCNAB1,ST8SIA2" Drug 5084_DN Resveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "ADRA1D,APBB2,APC,CDK10,FUBP1,RAB28,CLCN3,HAPLN1,VCAN,DTNA,ETV1,ANKMY1,SCML2,SEMA4D,TRAF3IP2,GAD1,SCIN,MAPT,TM6SF1,MID1,NF1,SAMD9,PID1,SUGCT,CCDC88A,SNCA,ZNF415,TCF4,TMPO,CABIN1,TRIO,FAM155A,OSBP2,XRCC4,PHTF2,TIGD6,SENP7" Drug 7301_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "ABHD6,ADCY6,CDC42BPA,KCNAB2,CDC14B,CDK10,SEMA4G,RAB26,OSBPL3,ARHGEF4,SPOCK3,DTNA,MTSS1L,FLT1,FYB1,SYT17,COPS8,GNG4,SPACA9,MAPT,MIA2,NFYA,GPR85,FA2H,PRPH,WDR25,TMEM231,RGS4,KCNIP1,SH3BP2,SLC11A1,TMCC1,UNC5B,SLC35G2,TIAM1,CHST5,ZNF711" Drug 7405_DN Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "AP2A2,MTUS1,SYNJ2,CA12,AP4M1,EPS15L1,CLCN3,GREB1,RHOBTB1,SGSM2,RASGRP1,EGR3,PCOLCE2,OLFM1,BAIAP2,TMEM164,SMC2,ATP2C1,MAP4K5,IL6ST,JAK2,PFKFB3,PIK3R1,FAM216A,SMOX,ING3,SUSD4,RET,SGK1,AMBRA1,PEX26,RCOR3,MYCBP2,CEP68,SATB2,TRIO,HIRA" Drug 5271_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "NDRG2,AK2,APC,EPB41L5,PLA2G4C,CFLAR,SLIT2,RAB28,CLCN3,BAG4,RASSF2,DBT,EXOG,MBNL2,ING4,FER,FGFR1,ZNF44,GPER1,PCLO,INPP5B,KITLG,PCDH9,SLC25A23,MBOAT7,PRKAR1B,NEK11,SLC9A5,SNCA,POGZ,PLCB1,TBCEL,NPL,KCNK12,ZNF45,EPM2A,PHTF2" Drug 7528_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "NME5,CFLAR,ST3GAL5,IL33,CLCN3,ABI3BP,CREM,PDE4DIP,CNTNAP2,CTH,ARHGAP32,FBXL5,PARD6A,RCAN1,MBNL2,EPB41L2,STX2,ETV1,FER,GPR37,GUCY1B1,MYO6,NOVA1,PLCD1,MAPK7,CSRNP3,MRAS,SH3BGR,KBTBD4,ELMO2,KDM4B,SPTAN1,CDK19,NXT2,SSBP2,UBE2H,MPPE1" Drug 6199_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "ASIC1,MTUS1,BIN1,APBB2,SLC4A4,NRP2,CACNA2D1,HIP1R,MAGI1,PDE4DIP,SLITRK5,MFAP3L,KLHL3,PLPPR4,MBNL2,MRNIP,ETV1,FERMT2,STON1,PCLO,KHK,MYO6,PFKFB2,CCSER2,PLCD1,CEP41,MAPK7,VPS13C,PPM1E,ANKRD6,DBNDD2,ST5,MCF2L,TCF4,KLC2,TRIM9,MAP3K12" Drug 6769_DN Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "ADRA1D,ALCAM,NCOA1,SLC4A4,BMP7,ARHGAP33,SLIT2,RCHY1,BAG4,RCAN1,MBNL2,STX2,NCALD,FAM198B,FGFR1,FHL1,DISC1,ARFIP1,GLYR1,RAB30,HTATSF1,GPD2,GSN,MAP4K5,HSF2,KCNF1,MPP2,NNAT,LIMCH1,SS18,PLCB1,ARC,ASTN2,TPM1,ZBTB14,MAP3K12,SMIM8" Drug 6825_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "NDRG2,SEMA4G,ARRB1,PDE8B,SLC4A4,ALDH7A1,ADAM23,AZGP1,BAIAP3,CLGN,RCBTB2,SULT4A1,SPOCK2,RUSC2,RASL12,ST3GAL6,FGF1,FYN,ALDH1L1,SRCAP,IL6R,KCNQ3,PDE4A,CEP41,MAPK10,SAMD9,ST6GAL1,FAM214B,SPART,ARC,WSCD1,TRIM2,ZKSCAN5,FAM155A,KCNK12,ZNF154,PARP11" Drug 3927_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.21E-04 1.00E+00 6.55E-03 7.38E-02 37 190 "NME5,LTBP4,MTMR2,CFAP410,CBFA2T2,QKI,AKAP7,RCHY1,TBC1D5,MFAP3L,EXOG,HIPK3,FCF1,IRAK4,GALC,RAB30,ADAMTS13,JAK2,KITLG,AFF1,MPP2,NF1,RETREG1,EPN2,KIF13A,KDM4B,ZBTB43,THSD1,ST5,ARC,PCDHA6,HEY1,RUNDC3B,FAM155A,VIPR2,EPM2A,AAAS" Drug 2480_DN Atovaquone [95233-18-4]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.43E-04 1.00E+00 6.59E-03 7.42E-02 35 177 "BRAP,ADRB2,PPFIA4,APAF1,CCNT1,RAB33A,IQCK,TSPAN5,FAM13A,ENO2,VPS26C,PTK2B,PCYOX1,ATP2C1,FYB1,AHDC1,HMGCR,ITGAM,PLCD1,PTPRN2,SEC14L1,ZNF821,SH3BP2,SLA,SLC2A5,SLC6A8,SLC11A1,ELMO2,KDM3A,SPP1,JMJD6,ZC3H4,ICAM5,TNS1,REEP1" Drug 6704_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADGRF5,PPFIA4,GAS7,ASPA,KSR1,CALB2,KCNAB3,ABCG2,CSF1,SUSD5,SPOCK2,PLPPR4,ELN,APC2,NRN1,GPER1,GRIK5,GRM2,ITGA7,SMAD1,CNOT4,NOVA2,PPP5C,MASP1,ZSCAN32,PTPRB,RGS12,RPS6KA2,SH3BP2,PKNOX2,SNCA,LHPP,ARC,TLR4,TPM1,VIPR2,PARP11,GAN" Drug 5592_DN troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,SEMA6A,BIN1,APBA2,APC,APOC1,ARHGDIG,PDE8B,MARK4,GYG2,CBFA2T2,CRLF1,SOCS6,ARHGEF10,HIPK3,COQ7,STX2,SEMA4D,CRCP,RAB30,RASSF8,MEF2C,MID1,NF1,PLEC,PPP2R2B,PRODH,RPS6KA2,SBF1,SH3BP2,MAPKBP1,PHLDB1,STX1A,WSCD1,KIAA0930,CABIN1,REEP1,PLSCR4" Drug 2844_DN Terconazole [67915-31-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,CDC14B,MARK4,NUMB,EIF4G3,SYNJ2,CAMK2G,PLEKHB1,TAOK2,QKI,ENTPD4,GIT2,SGSM2,FEM1B,SUGP2,EIF5,ENO2,KAT8,FHL1,ERAP1,GLYR1,GPD2,IPO5,MAP4,GIT1,CNOT4,SETD4,NKAIN1,RIC8B,TCP11L1,SIRT2,KDM4C,ERC1,THSD1,EXOC7,FRYL,WRN,PHTF2" Drug 7478_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BEGAIN,AMH,APOC1,ARHGDIG,MARK4,SLC4A4,ALDH7A1,SYNJ1,C5,RUNX1T1,HOMER3,CREM,ENTPD4,CRY2,SIPA1L1,SEC14L5,MFAP3L,HIPK3,MBNL2,ERCC2,KAT8,FGFR1,BAIAP2,OGA,GPR37,RNFT2,DHX35,KCNH2,LMO2,MAP4,MAPT,ZMAT4,PNMA8A,MAPK12,FAM214B,ANKRD12,KIAA0930,ZNF24" Drug 3399_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AP2A2,APAF1,KCNAB2,MARK4,ATP2A2,CAMK2B,CNTN1,AKAP6,SNCAIP,RUSC2,C2CD2L,ERCC2,FHL1,AFF2,GAD1,SIGLEC8,GRIK5,NXPH3,HLF,TJAP1,KIF5A,MAP2,MX1,MYO7A,NEFM,NELL2,MAPK7,ENOX1,RFX3,NUDT11,KLHDC8A,PKNOX2,UNC5B,ZC3H13,NXT2,VLDLR,PHTF2,SENP7" Drug 2908_UP Nifurtimox [23256-30-6]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ACTN1,NDRG2,ANK2,PDE8B,ATP6V0A1,MTMR2,HAP1,CDO1,HOMER3,WHRN,CNTNAP2,KLHL3,DMD,EPB41,PDLIM5,ATXN2L,MYO7A,PDE4D,NLE1,FA2H,PPARA,LRRN3,PRKAR1B,PTPN13,RASGRF1,FAM102A,ST6GAL1,BTBD7,SMARCD3,ARHGAP26,SPTAN1,SPTB,SYT5,CDK20,RUNDC3B,FLRT2,SH3GLB2,PARP11" Drug 1219_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APOC1,PPFIA3,SHROOM2,STX16,BACH1,CFAP410,ARHGEF2,ZMYM4,EPS15L1,ARMC8,ABI3BP,CRY2,GIT2,EDIL3,STX2,FGF1,SEMA4D,DLL3,FYB1,SYT17,INPP5K,ALDH1L1,STON1,AFF1,MMP16,NACA,OXTR,PDE4D,PIK3R1,RETREG1,LRRN3,HSPA4L,PDZD2,KDM4C,ZBTB43,PHLDB1,ARHGEF9,MTCL1" Drug 6924_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,BRAP,CDK10,ARNTL,ARRB2,SYNJ2,SPAG9,C2CD2,PDE4DIP,RCAN1,CDKL3,PRKAG2,PDLIM5,INPP5K,AHDC1,HTATSF1,KCNMB4,TJAP1,IL6ST,IPO5,MAP4,NPR2,CCDC25,AP1AR,TRA2B,ABLIM3,BTBD7,CDK5RAP2,ERC1,FBXW11,KAT6B,METTL3,TSC2,HIRA,UBTF,LMF1,FIP1L1,PHTF2" Drug 6619_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,ANK2,APAF1,APBB2,ATP1A3,AZGP1,RUNX1T1,ARHGEF1,ARHGEF2,FOXN3,ENTPD4,AKAP12,VCAN,SPOCK2,CHRDL1,DTNB,HEYL,CELSR3,FGF1,FGFR1,GPER1,LSAMP,MGAT3,MMP16,MYH3,PFKFB4,PLXNB1,PPP2R2B,VPS13C,PTPRB,ZSCAN2,PID1,RFX2,ZHX3,PHLDB1,VLDLR,ZNF74,KCNAB1" Drug 5410_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NME5,EPB41L5,ARHGDIG,ALDH7A1,SLIT2,BAG4,ENTPD4,SH2B1,SIPA1L1,DCAF8,ING4,KAT8,ZNF589,FGFR1,BAIAP2,CINP,OGA,SRCAP,MSL3,GPER1,ELOVL5,HNMT,IL6ST,INPP5B,IPO5,LSS,MBD1,MPP2,NCAM2,PRKAR1B,PRODH,ZDHHC14,GTDC1,RGS12,RBM34,EXOC7,TRIM2,ZNF45" Drug 2233_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AMT,APBA2,APOC1,CFLAR,GYG2,CACNA1A,SYNGR3,ARHGAP33,FAM189A2,SIPA1L1,SEC14L5,TMCC2,CDON,EDNRA,ANKMY1,SCML2,FHL1,IQCG,GNG4,CACFD1,ICA1,MIA2,MMP16,MYO7A,CDK18,PRKAR1B,PRODH,RXRA,PREX2,STX1A,VPS13A,PCDHA6,FAM155A,FLRT2,VLDLR,WIPF1,KCNAB1,PHTF2" Drug 6771_DN Monocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "PPFIA3,ARRB1,STX16,ATP6V0A1,SYNJ2,LRBA,CNOT8,SLIT2,RAB28,MFAP3L,LYPD1,EDNRA,FGFR1,PDLIM5,DISC1,INPP5K,SRCAP,GLYR1,HTATSF1,GRB10,MAP4K5,INPP5B,NEK1,NNAT,PPP5C,ZCWPW1,CLIP1,ZNF821,ERC1,UNC5B,SPART,THSD1,SS18,NXT2,ARC,EMSY,SMIM8,PHTF2" Drug 3442_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APBB2,APC,PPFIA3,ARRB2,CDK13,SYNJ2,LDLRAD4,HOMER3,GREB1,DCAF8,RCAN1,EGFR,AGAP2,FAM49B,INPP5K,GCNT2,POLL,GPD2,GSN,KHK,MAP4,MBD1,KITLG,MYO6,CDK18,GPR85,PLEC,SLC25A23,PTN,RGS12,TCP11L1,ANKRD6,SPART,CEP68,CLDND1,ZNF24,NT5M,EPM2A" Drug 7046_UP PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AP2A2,BIN1,CDK10,CAMK2B,PLAA,QKI,CNTFR,DZIP3,RIMS2,CELSR3,ING4,ZNF589,FER,USP19,MSL3,SHISAL1,MX1,PALM,POLG,PRKAR1B,PTCH1,GAL3ST4,RPS6KA2,ZNF821,SLC9A5,KDM4C,ARHGAP26,EXOC7,SMG6,TIMP4,TNS1,FAM155A,EIF4ENIF1,REEP1,NT5M,EPM2A,SMIM8,TIGD6" Drug 4653_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYT13,APC,PPP4R4,N4BP2L1,IL33,KALRN,USP2,DLGAP1,COL9A3,RGS6,TOM1,SRPK3,ERBB4,NRN1,POLL,GNAL,GPD1,KCNF1,KCNJ5,MAP2,ADAM11,AFDN,PALM,PPP2R2B,CNNM2,KLHDC8A,TCP11L1,MRAS,SLA,SNAP25,SPP1,SPTB,ARC,TLR4,CHST5,TRO,UBE3A,KCNAB1" Drug 3727_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADD2,LTBP4,CDK10,NRP2,CHN2,CNTFR,CNTNAP2,DAPK3,DTNB,ECM2,EDNRB,PLXNC1,MTSS1L,KAT8,FGF12,CAMKK2,GPD2,ICA1,KCNJ5,KCNQ3,TM6SF1,NFYA,PTPRN2,GAL3ST4,RGS4,STK32B,RXRA,FBXO11,FNDC3A,PEX26,ARHGEF40,SLC11A1,ARC,ADGRL3,RPGRIP1L,KCNAB1,FZD3,RNF146" Drug 7311_UP Tiletamine hydrochloride; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,ALK,CDK10,ALDH7A1,SCAPER,CFAP410,RUNX1T1,SOCS6,PPP6R2,EDNRA,HIPK3,CELSR3,AASS,RRAGB,FGF1,SYT17,GLYR1,GNAL,MIA2,AFF1,NRCAM,PALM,PIK3R1,CCSER2,POLG,ZNF821,ZFP30,SH3BP2,AMBRA1,ANKRD6,SNCA,KIF13A,SPTAN1,JMJD6,RPGRIP1L,SYNE1,CRTC1,DNAH7" Drug 2695_DN genistein; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,BRAP,AMT,APAF1,ADAM23,CAMK2G,HOMER3,CSF1,SLITRK5,HDAC9,MAML1,DTNA,PCOLCE2,ELN,COQ7,ANKMY1,AFF2,CAMKK2,GATM,ZNF276,GNG4,GPD2,IRF8,ITGA7,LSS,MAP4,MATK,MEST,CNOT4,PDE4A,POLG,BCAS3,PTCH1,RET,DDN,KANK1,PLCB1,TNS1" Drug 2501_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,NDRG3,DOC2A,TRMT9B,AMPD3,APBB2,PPP4R4,CAMK2B,RUNX1T1,USP6NL,EIF4G2,CDKL3,DLC1,PRELID3A,CSPG5,GCNT2,HTATSF1,NCKAP1L,MAP4,MID1,MYO7A,NFYA,SETD4,PFKFB2,MAPK7,BCAS3,PTCH1,GAL3ST4,SH3BP2,FRMPD1,SLC11A1,BTBD7,DOK5,TROVE2,CRTC1,HSPBP1,LMF1,UBE3B" Drug 5400_DN S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "RALGAPA1,ASPHD1,APOC1,TAOK2,ENTPD4,DBN1,ZNF804A,SGSM2,DTNA,OPTN,MBNL2,KAT8,ZNF589,OGA,GALC,INPP5K,GCNT2,AHDC1,GPER1,GRIK5,MPP2,LYRM9,NF1,OGG1,NLE1,MINDY2,PRODH,MSANTD2,RGS12,SBF1,CLSTN2,THSD1,PLCB1,CRTC1,TK2,UPF3A,SEMA3B,EPM2A" Drug 7476_UP Penbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APC,GAS7,PLA2G4C,SLC4A4,MTMR3,CAMK2G,STOML1,QKI,ENTPD4,NCOR2,ARMCX2,TMCC2,DMPK,DRP2,RCAN1,GNG4,JAK2,LMO2,MATK,MMP16,NF1,NOVA2,SLC25A23,PLXNB1,MBOAT7,PPP2R2B,GDPD2,RIPOR1,SH3BP2,SLC2A5,BTBD7,SNCA,STX1A,TRIM2,PIK3R5,FAM155A,ZBTB14,TFIP11" Drug 7350_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AP2A2,AMPD2,BCAS1,PPFIA3,CFLAR,C5,TAOK2,SLC4A8,CSNK1E,CTH,LYPD1,DTNA,FCF1,ITPKB,KCNH2,LIG4,MATK,KITLG,MITF,NCAM2,NFYA,PLEC,PRKAR1B,CEP97,GSTCD,NEK11,ATXN2,ZKSCAN3,CLASP2,EXOC7,VIPR2,ZBTB14,DNALI1,GDPD5,KCNAB1,MPPE1,UBE3B,AAAS" Drug 2484_UP Terconazole [67915-31-5]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BEGAIN,PKP4,PRX,PLA2G4C,ATP6V0A1,SCARB1,TAOK2,DAPK3,C3orf18,RASGRP2,ZNF549,FGFR1,PDLIM5,CAMKK2,TMEM8B,GLI2,GLYR1,NCKAP1L,IL6ST,KCND1,MAP4,MPP2,MX1,NELL2,NINJ2,CNOT4,NTRK2,CCSER2,PTPN13,ASAP3,LIMS2,SNCA,ARHGAP26,ATP10B,SEPT8,WSCD1,TEK,AMACR" Drug 3447_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ARHGDIG,SLC4A4,SYNJ1,FOXN3,TAOK2,PDE4DIP,SEMA3D,EGFR,ERCC2,NCALD,SEPT9,ALDH1L1,PCDH17,GNAO1,DIDO1,SPACA9,GRIK5,JAK2,MAP4,NF1,NNAT,SMOX,PPP2R2B,PRKAR1B,ZDHHC14,SH3BP2,EPN2,FAM214B,SLC11A1,ATP10B,ZC4H2,PHLDB1,STX1A,WSCD1,KIAA0930,PCDHA5,VGF,SLC30A3" Drug 7462_DN DO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MARCH3,SLC25A14,LHX2,HOMER3,PPP6R2,HDAC4,KIAA0586,GIT2,DBN1,C2CD2L,LYPD1,PARD6A,GRB10,DIDO1,PADI2,IDH3B,KCNF1,IPO5,MEIS1,MITF,NACA,NFYA,OXTR,KCTD15,PLEC,PPP5C,ARFGAP1,RCOR3,PDZRN3,ZBTB43,SPART,ARHGEF9,TACC1,ZNF24,ZNF32,MAP3K12,EMSY,SMIM8" Drug 6212_DN Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "PKP4,ARRB2,ZBTB10,SCARB1,RAB28,DCAF8,ZNF337,GIT2,DBT,DCTN1,FEM1B,FCF1,RACK1,NBEA,CINP,PDLIM5,FAM49B,SYT17,ARFIP1,MAP4K5,IL6ST,OXTR,PRKAR1B,PTPN13,TCP11L1,SUPT20H,AMBRA1,KBTBD4,SMARCC2,NSFL1C,KLHL7,ANKRD12,TBL1X,TIAM1,KAT6B,HIRA,VAV1,MPPE1" Drug 1781_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; HL60; HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ALCAM,AMT,APAF1,N4BP2L1,PTBP2,LRBA,CLTB,DOCK4,ZBTB24,FEM1B,SUGP2,ERCC2,VPS26C,ZMYND10,TRMO,POMT1,ADAMTS13,PADI2,SCAMP5,AFF1,NFYA,OGG1,RETREG2,DEF8,RNASEL,SUPT20H,FNDC3A,SLC11A1,SPART,VPS13A,FAM208A,OBSL1,KAT6B,TRPM2,ZKSCAN5,PLPPR2,LAMP5,URM1" Drug 6099_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,NME5,ALCAM,KCNAB2,EPB41L5,ARRB1,MARK4,SLC4A4,GYG2,CACNA1I,LHX2,FAM189A2,SLC4A8,RCHY1,CSF1R,DAPK3,GIT2,DTNA,PLXNC1,VPS13B,PRELID3A,SEPT9,POLL,RASSF8,IL6ST,JAK2,MPP2,GIT1,ADAM22,NEK1,LRP12,ZNF821,PEX26,SNCA,KIF13A,KDM4C,ELOVL4,CEP68" Drug 4231_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYN3,ASIC1,ADORA1,APC,ADAM23,CALB2,NRXN3,SNX29,RASGRP2,EPHB1,PIPOX,FGFR1,AFF2,EFCAB2,NSG1,GABRA3,PCDH17,ICA1,PACRG,MAP2,AFDN,MMP16,ADAM22,PDE4D,MAPK10,PTPRD,ACSS3,RASGRF1,RGS4,MAST1,ZNF415,NFASC,PHLDB1,ADGRL3,SZT2,ZNF24,ZNF154,SLC17A7" Drug 2970_DN Loracarbef [121961-22-6]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,ADD1,AP2A2,BIN1,SLC4A4,ATP6V0A1,BACH1,SYNJ2,CLGN,SOCS6,CSF1,DZIP3,DGKG,RUSC2,RCAN1,EIF4G2,EIF1,FGFR1,PDLIM5,ADAM28,GPD2,CACFD1,GSN,MAP4K5,ITGA7,NINJ2,SMOX,SLC25A23,STRN3,MAPK3,RNASEL,ANKRD6,SLC2A5,KDM4B,ZEB1,XRCC4,MAP3K12,KCNAB1" Drug 4736_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASIC1,ATP2B2,SCAPER,MTMR7,CYBB,SPOCK3,SRPK3,C3orf18,RASGRP2,PTK2B,DLC1,FGFR1,FHL1,EFCAB2,LPAR4,SPACA9,GRM8,SYNPO,KCNJ5,AFDN,ADAM22,NPY,NTRK2,PALM,CDK18,MAPK7,PTN,C1orf54,NLGN1,SLC11A1,ZNF415,PEG10,TAL1,AMACR,LAT2,KCNAB1,TIGD6,JPH3" Drug 703_DN genistein; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BRAP,BIN1,CDC42BPA,PPFIA3,SLC4A4,EIF4G3,MPDZ,BCL7A,EPS15L1,NCOR1,PPP6R2,COQ7,FGFR1,RUNDC3A,TXNL4A,CRCP,BTN2A1,HAS2,JAK2,KCNJ5,NELL2,MAPK7,MAPK10,RBBP6,NUDT11,CLIP1,SBF1,MAPKBP1,ZHX3,CLASP2,EXOC7,FBXW11,ZEB1,HEY1,TRIO,WIPF1,NPDC1,REEP1" Drug 2218_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APC,EPB41L5,PPFIA3,PLA2G4C,MARK4,SLC4A4,ATP6V0A1,KIF1A,MTMR3,CAMK2B,CLGN,FOXN3,AKAP7,ARMC8,ENTPD4,ABCG1,ZNF804A,DNM1,COQ7,SCML2,FHL1,FAM49B,PRELID3A,CSPG5,GNG4,GPER1,SPACA9,GSTM5,ATXN2L,IL6ST,PRKAR1B,TMEM104,SEC14L1,IQSEC2,TBL1X,TNS2,TMEM121,THRA" Drug 441_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,ARHGDIG,ARRB1,PDE8B,C5,DLGAP1,CHGB,CHRNA4,ARHGEF4,KLHL3,DTNA,NCALD,PIPOX,FGFR1,BAIAP2,IQCG,RUNDC3A,HPGDS,GPR37,GRIK5,SOX21,NFYA,NOVA1,MASP1,PTCH1,MTMR10,SUSD4,RGS3,ATXN2,FUZ,SLA,SLC9A5,KBTBD4,POGZ,EXOC7,CDH22,ZNF74,ZNF184" Drug 4654_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYN3,TRMT9B,AMPD3,ASPA,RGS11,NRP2,CAMK2B,DLGAP2,CHGB,LY86,AKAP5,ABCG1,RIMS2,HS3ST2,CELSR3,HSD17B14,RASGRP2,NCALD,APC2,FGFR1,FYN,ERAP1,SIGLEC8,PCDH17,CACFD1,AP4S1,SOX21,SMAD1,AFDN,NOVA2,PCDHGC3,MINDY2,PTPRN2,SCN2B,SYN2,PCDHGA10,CDK20,KCNAB1" Drug 2837_DN Propylthiouracil [51-52-5]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "EP400,CDC14B,ST3GAL5,CCNT1,LHX2,RAB26,COL4A5,CREM,NCOR1,PDE4DIP,DZIP3,DPH1,ABCC5,ING4,TNK2,SEPT9,KCNMB4,PRRC2B,CACFD1,RNFT2,MAPT,LYRM9,PRPH,SIRT2,BTBD7,ZKSCAN3,FNBP1,TROVE2,VPS13A,COBL,IQCE,NSD1,TPM1,PLPPR2,LMF1,MAP3K12,SEMA3B,EPM2A" Drug 1671_DN Meticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NUMB,BCL7A,CFLAR,HOMER3,PDE4DIP,B3GAT3,DTNA,SUGP2,CDKL3,EZH1,FER,FAM49B,GALC,SEPT9,MAP4K5,TJAP1,FAM69A,MAN2A2,MAP4,MAPT,SLC25A23,ZCWPW1,SH3BP2,KIF16B,PEX26,LHPP,TROVE2,POGZ,ELOVL4,NSFL1C,MTCL1,EXOC7,SIN3B,CDK20,HIRA,PLPPR2,EVI5,SEMA3B" Drug 5939_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYT13,BIN1,CDK13,ATP2A2,ADAM15,ADGRB2,NRP2,CALB2,SYNGR3,NRXN3,AKAP7,PDE4DIP,TBC1D5,MFAP3L,SPOCK3,ETV1,MAP4K5,RASSF8,TJAP1,KCNJ5,KCNN1,GPR85,CCSER2,RETREG1,PLEC,POLG,PTN,FBXW7,SEMA6D,SAMSN1,PLCB1,TIAM1,CABIN1,VGF,CLDND1,ZNF74,EPM2A,GJC2" Drug 1778_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ACTN1,APOC1,N4BP2L1,MTMR3,CA12,P2RX6,CHN2,SLIT2,PICK1,IQCK,PCYT1B,OSBPL3,MED12,EEF1D,PIPOX,FYB1,HIGD1B,AHDC1,ADAM28,RUNDC3A,CRCP,GPR12,SCAMP5,LYRM9,NLE1,PLTP,DEF8,RGS12,RNASE1,TCP11L1,PREX2,FAM214B,IZUMO4,ST5,TLR4,SMUG1,TRPS1,ZNF142" Drug 3939_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BEGAIN,APLP1,ADGRB2,CACNA1I,CFAP410,CAMK2B,STOML1,WHRN,CABP1,NCOR2,RIPOR2,DGKG,DAPK1,PLXNC1,ERCC2,OLFM1,FGFR1,DCTN2,NSG1,GNAO1,ICA1,ITGAM,KCNH2,L1CAM,MARK1,MYCN,NPR2,NTRK3,DIRAS2,PNMA8A,STUM,ASAP3,SPP1,SSTR2,SYNE1,TEK,PIK3R5,SLC30A3" Drug 4997_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYN3,SEMA6A,SCAPER,BAIAP3,CA4,CLGN,HOMER3,CNTN1,NRG2,TBC1D5,SPOCK2,EDN1,HIPK3,VPS13B,DLC1,OGA,GRIK5,DHX35,ICA1,LIFR,NF1,NTRK2,PCDH9,PDE4A,PRKAR1B,PNMA8A,SBF1,SH3BP2,SLA,CCDC88A,KDM4B,RGL1,HIRA,UCHL1,EMSY,SEMA3B,SLC17A7,EPM2A" Drug 2306_DN Salbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,APBB2,APOC1,ARRB2,MARK4,SCAPER,HIP1R,B4GALT6,CRY2,FAM169A,PPP6R2,DCAF8,TBC1D5,DAPK3,PHF20L1,COQ7,ANKMY1,FHL1,POLL,HNMT,INPP5B,MAP4,PALM,RETREG1,NLE1,PRPH,FAM184A,TRIM68,FBXW7,FNDC3A,SMARCA4,SMARCD3,MAPKBP1,CDK19,DOCK9,CHST8,KLC2,GDPD5" Drug 7014_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,APBA2,SCAPER,CBFA2T2,ENTPD4,DAPK3,TOM1,EDNRB,F5,PRKAG2,SEMA4D,AFF2,FAM49B,FYB1,ATXN2L,KCNF1,KCNH2,KCNJ5,KCNN1,MID1,LYRM9,NF1,PDE1C,PRODH,CNNM2,GSTCD,TTC17,SNCA,SPTB,RPGRIP1L,PCDHGA10,TNS2,ZNF34,CABIN1,VIPR2,VLDLR,LAT2,ST7" Drug 7523_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,ADORA2A,SPARCL1,ALCAM,BIN1,APAF1,MARCH3,MARK4,GYG2,BAIAP3,FOXN3,NCOR1,DCAF8,FOXF2,SRCAP,COPS8,GNG4,GRB10,MAP4K5,HNMT,MPP2,NNAT,DUSP26,PLTP,PPP3CC,SNRK,WDR25,UNC5B,CLASP2,ST5,CHST5,VIPR2,KCNK12,REEP1,EMSY,GDPD5,ITM2C,UBE3B" Drug 2873_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,ADRA1B,ALK,AMPH,APLP1,ATP2B2,DLGAP2,EPS15L1,FAM149A,ABCG1,CRYM,SNCAIP,ELMO1,SRCAP,PCDH17,GPR75,ITPKA,KCNJ5,AFDN,NELL2,NNAT,NPY,GPR85,ZMAT4,TRIM68,EMID1,RASA3,FRMPD1,ST6GAL1,PKNOX2,ARHGEF40,SPTB,ARC,TMEM121,ZFPM2,EVI5,ITM2C,ADAMTSL3" Drug 5069_DN Gemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NME5,APOC1,ARRB2,MARK4,AP4M1,TPP1,HOMER3,BAG4,VCAN,PARD6A,EDIL3,FAM13A,MBNL2,ANKFY1,EFCAB2,TRMO,DENND2A,HSF2,SHISAL1,MBD1,MIA2,MX1,SLC11A2,PLXNB1,MAPK7,TCP11L1,SCN8A,ASAP3,DZIP1,ELMO2,TMCC1,ZBTB43,THSD1,TIAM1,METTL3,UPF3A,MAP3K12,FZD3" Drug 7019_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "CDC42BPA,PKP4,APBB2,APOC1,PPFIA3,CDC14B,ARRB2,EIF4G3,LHX2,PLAA,MAP4K4,HOMER3,CDC42BPB,PUM1,ZNF337,GIT2,PARD6A,SUGP2,BAIAP2,EFCAB2,GRB10,RNFT2,HSF2,NF1,OPA1,SLC25A23,SMIM7,PPP3CC,PRKACB,EPN2,DOP1A,SOX3,ANKRD12,BHLHB9,TFIP11,MAP3K12,GDPD5,GAN" Drug 3978_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF1,BIN1,APAF1,KCNAB2,CDC14B,NRP2,KALRN,SEPT7,CLGN,WHRN,AATK,GSDME,SPOCK3,DRP2,REEP2,FHL1,NEU3,LYVE1,POLL,PCLO,GRM8,AP4S1,SHISAL1,MEF2C,MMP16,MASP1,PTPRH,RASGRF1,KHDRBS2,RNASE1,KANSL3,ARHGEF40,NMNAT2,IZUMO4,DOCK9,TRPM2,ZNF711,ADAMTS9" Drug 6017_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,FAM131A,CDC14B,NCOA1,EIF4G3,BCL7A,MTMR3,GYG2,SYNGR3,QKI,BAG4,CNTNAP2,GREB1,DCAF8,LYPD1,RHOBTB1,DTNA,FYN,GHR,GLYR1,MSL3,SLC2A6,IL6ST,INPP5B,ITPKB,KCNF1,MAP4,NF1,SMIM7,PRODH,RIPOR1,SH3BP2,ZNF430,BTBD7,SPTAN1,PLCB1,ANKRD12,SSBP2" Drug 5202_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,ALK,SYT13,MARK4,GYG2,RUNX1T1,ASIC3,CHRNA4,CRY2,CSF1,ZNF804A,RUSC2,EIF4G2,DLC1,FGFR1,GAD1,GNAO1,STON1,GPER1,SPACA9,GRIK5,SLC2A6,MID1,MX1,ZNF862,NF1,PCDH9,NECAB2,ZNF821,FAM214B,ARHGEF9,SYN2,EXOC7,ADGRL3,PCDHGA10,RUNDC3B,FLRT2,JPH3" Drug 4535_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,BIN1,ARRB2,KIF1A,BAIAP3,AKAP5,ABCG1,PDE4DIP,CNTNAP2,EXOG,DMPK,EDNRA,CNNM1,MBNL2,TNK2,SPEG,ETV1,BAIAP2,ERAP1,TDRKH,INPP5B,ITPKA,LSS,MX1,NDP,SAMD9,FBXW7,FAM192A,SAFB,DZIP1,CRTC1,TIAM1,LMF1,ZBTB14,NT5M,HPS4,KCNAB1,SMIM8" Drug 6249_UP Thiorphan [76721-89-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADD2,PTCH2,SLC2A11,BCL7A,KSR1,MTMR2,CA4,CCNT1,CBFA2T2,CDH2,PLEKHB1,ARHGEF10,MAMLD1,EDNRA,SEMA4D,GLYR1,CACFD1,GSN,KCNF1,KCNJ5,NTRK3,SAMD9,KHDRBS2,RGS12,DCUN1D2,RASA3,RBM34,ARC,TCF4,PCDHA5,TMEM121,CABIN1,TNS1,PLPPR2,LMF1,XRCC4,ZNF74,PHTF2" Drug 1492_DN Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,CDK10,CDK13,BMP7,SYNJ2,SCARB1,FOXN3,CNOT8,SLIT2,CRY2,GIT2,SLC12A6,FEM1B,FCF1,SUGP2,VPS26C,EZH1,ZNF589,FAM49B,PRELID3A,COPS8,GNG4,HSF2,IL6ST,LIG4,CNOT4,MBOAT7,PPP2R2B,PPP3CC,PPP5C,GSTCD,FUZ,ZHX3,TROVE2,SS18,ARHGEF9,SYT1,MAP3K12" Drug 2565_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "TRMT9B,APC,CDC14B,SLC4A4,N4BP2L1,SYNJ2,LDLRAD4,CAPN3,RAB33A,TPP1,CPS1,VCAN,PPP1R16B,ZNF337,CDON,DTNA,TOM1,FEM1B,MTSS1L,PIPOX,DLC1,MAP4,MEF2C,N6AMT1,CNOT4,RETREG1,PLTP,PMP22,MAPK7,RIPOR1,CNKSR2,MAPKBP1,CEP68,RGL1,CRTC1,LMF1,XRCC4,ZNF32" Drug 2433_UP Felodipine [72509-76-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADORA1,MTUS1,SEMA6A,BCAS1,PPFIA3,KIF1A,BMP7,CACNA2D1,CDH2,CACNA2D2,CREM,AATK,SIPA1L1,DZIP3,RIMS2,ERBB2,TBC1D16,HPCAL4,PCLO,TJAP1,KCNN1,ADAM22,MX1,MYO6,NFYA,NOVA2,NTRK2,MAPK7,SUGCT,SEMA6D,SH3BGR,SOX15,SEPT8,RPGRIP1L,FLRT2,LMF1,MKRN3,SLC30A3" Drug 4968_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NME5,SCAPER,LDLRAD4,CBFA2T2,CLGN,SOCS6,ARHGEF6,ARMC8,CPS1,CTH,DCAF8,RUSC2,EGR3,ING4,SEMA4D,GNAO1,STON1,KCNH2,KCNQ3,KPNA5,LSS,TM6SF1,ADAM22,ZNF862,MTRF1L,MINDY2,PTPRO,ZNF493,RGS12,KCTD17,TCP11L1,CPEB3,ZNF423,RGL1,SYN2,ZEB1,HIRA,LAT2" Drug 438_DN copper(II) sulfate pentahydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BRAP,APBA2,NCOA1,LHX2,STOML1,AATK,ARHGEF10,DZIP3,C2CD2L,KLHL3,EXOG,HIPK3,MBNL2,RASGRP2,CDKL3,TMEM8B,MALT1,BTN2A1,RNFT2,KCNF1,MMP16,NPR2,PDE1C,PLCD1,POLG,PRODH,MASP1,PTPRN,RIPOR1,TCP11L1,ST6GAL1,SLA,SLC11A1,ELMO2,TAL1,TNS1,ZIC1,MPPE1" Drug 6314_UP Vigabatrin [60643-86-9]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "TRMT9B,SEMA7A,APAF1,SYNJ1,CACNA2D1,CBFA2T2,PLAA,TPP1,HAPLN1,ABCG1,PDE4DIP,HDAC9,ARHGAP32,COQ7,BAIAP2,INPP5K,ZNF276,HSF2,IL6ST,MYO7A,NF1,GPR85,PLCD1,PPP2R2B,MAPK10,BCAS3,DZIP1,ELMO2,TTC17,PHLDB1,SMG6,THRA,TPM1,TPM2,AMACR,NDRG4,NT5M,EVI5" Drug 7153_UP Pyrithyldione [77-04-3]; Up 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADRA1D,PPFIA3,KYAT1,RAB28,HOMER3,BAG4,HAPLN1,OSBPL3,VCAN,CNTNAP2,DAPK3,MFAP3L,SPOCK3,CDON,DMTF1,ANKMY1,FAM49B,FYN,GAD1,TMEM8B,ACOT7,KCNJ5,MAPT,ZNF862,NPR2,RAD51D,SUPT20H,NLGN1,FAM214B,BTBD7,ARFGAP1,ARHGAP26,ARHGEF9,VPS13A,CABIN1,ZNF711,EVI5,EPM2A" Drug 2465_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C3orf14,AGT,BCAS1,KSR1,BMP7,GYG2,AKAP6,CREM,CRYM,RASGRP2,F5,FER,BAIAP2,GAA,SEPT9,GPR75,HNMT,MAP4,MYT1,PFKFB4,PPARA,LRRN3,TMEM104,TCP11L1,GALNT10,NLGN1,ZC4H2,SYT5,PCDHGB6,PHF24,TIAM1,TRIO,FAM155A,CLIP2,WNT7A,KLC2,KCNAB1,PLSCR4" Drug 7061_UP SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,KCNAB2,CA4,FOXN3,LHX2,QKI,HOMER3,CRY2,ABCG1,LRIG1,CYBB,DTNA,STX2,BAIAP2,FHL1,ERAP1,AHDC1,CACFD1,LMO2,MGAT3,NPR2,SLC11A2,PLCD1,POLG,RIPOR1,RGS12,RNASEL,GSTCD,ZNF821,TROVE2,POGZ,ST5,PHLDB1,EXOC7,KIAA0930,CHST8,REEP1,UPF3A" Drug 1311_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,GAS7,CDK13,STX16,N4BP2L1,SPAG9,FOXN3,ARMC8,RNF14,TBC1D5,DBN1,DBT,RCAN1,FAM13A,FCGRT,HTATSF1,MAP4K5,HSF2,ICA1,INPP5B,MBNL1,NF1,MINDY2,SAMD9,PTK2,RET,ELMO2,SS18,NXT2,SYPL1,FBXW11,TLR4,ELP5,UBE2H,LAT2,CLDND1,ZNF45,MPPE1" Drug 3376_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADORA2A,ADRA1D,TRMT9B,CDC42BPA,SULT4A1,CSF1R,GSDME,MBNL2,TNK2,LRRC17,GRIK5,NXPH3,ITGA7,LMO2,MBP,MYCN,NEK1,NELL2,NF1,PFKFB4,CCDC40,LIMS2,SNCA,HECW1,SPTB,CLSTN2,SYT5,WSCD1,ZEB1,SZT2,CRTC1,CHST5,FLRT2,VLDLR,SPHK2,SLC30A3,NT5M,ADAMTS9" Drug 3361_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,BRAP,AGT,NME5,APBA2,ATP2B2,CACNA1I,ARHGEF1,WHRN,CRMP1,CNTNAP2,SPOCK3,DTNA,EPHB1,SPEG,PIPOX,PTK2B,CORO2B,ZNF589,FHL1,FOXF2,RASL10A,ADAMTS13,KCNQ3,MATN3,AFF1,MMP17,TAGLN3,NF1,NPTX2,PAX6,ENPP2,TRIM68,SEMA6D,CXXC4,PCDHGA10,TRPM2,DNALI1" Drug 5482_UP Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BEGAIN,KCNAB2,GAS7,FAM131A,STX16,MTMR2,BAIAP3,CACNB4,DLGAP1,TAOK2,RAB33A,SULT4A1,CSF1,CSF1R,GPRASP1,JAKMIP2,EIF4G2,OLFM1,AGAP2,RASL10A,SRCAP,CNTRL,MAN2A2,GIT1,NFYA,LRP12,SH3BP2,ARHGEF40,BTBD7,ZKSCAN3,COA1,SOX11,PEG10,ZC3H13,RBM26,EXOC7,PCDHGB6,EVI5" Drug 6161_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,APOC1,CDC14B,BMP7,CACNA1G,CFAP410,CACNB4,LARGE1,CREM,ING4,TUBD1,RCAN2,RASGRP2,ETV1,F5,DLC1,AGAP2,ZNF44,ICA1,MAP4,ADAM22,MYO7A,NF1,NRCAM,BEND5,RFX2,ZFHX4,ST6GAL1,CNKSR2,SLC8A1,FAIM2,HECW1,LMO3,TROVE2,VSNL1,MKRN3,KCNAB1,PARP11" Drug 1406_DN Norfloxacin [70458-96-7]; Down 200; 12.6uM; HL60; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,APAF1,APBB2,ATP6V0A1,CD38,TAOK2,EPS15L1,TM9SF4,RCAN1,FEM1B,TRMO,POMT1,LILRA2,GRB10,CACFD1,SCAMP5,MPP2,MYO5A,NEFH,NF1,NFYA,SLC11A2,CNNM2,C12orf49,ATXN2,SGK1,CCDC88A,SMARCC2,ARHGAP26,DIP2A,NSFL1C,TBL1X,DICER1,PIK3R5,UBE3A,ZNF24,HPS4,URM1" Drug 3362_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASIC1,APC,MARCH3,CFLAR,USP2,ARHGAP33,TAOK2,ARHGEF10,CTH,JAKMIP2,RCAN1,DTNA,EGFR,STX2,FGFR1,TPK1,INPP5K,GCNT2,TM6SF1,MEIS2,ADAM22,PLCD1,PLXNB1,PPP5C,GRAMD1C,TCP11L1,SBF1,PEX26,SOX3,TROVE2,PLCB1,KIAA1107,ZNF34,VLDLR,XRCC4,NDRG4,REEP1,GDPD5" Drug 6867_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASPHD1,MARCH3,ADAM23,CACNA2D2,RCBTB2,SOCS6,QKI,IQCK,PDE4DIP,DAPK3,RCAN1,ARMCX1,PTK2B,BAIAP2,PDLIM5,TRAF3IP2,POLL,CNTRL,MAP4K5,NDP,NFYA,OCRL,PDE4A,PDPK1,FSD1,MAPK7,SBF1,BTBD7,CDK5RAP2,ZNF415,KDM4B,SPTB,LHPP,DICER1,BEX4,LMF1,ZNF74,SEMA3B" Drug 3797_DN Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADGRF5,PKP4,SLC4A4,NRP2,CBS,ARHGAP33,QKI,PICK1,ETV1,USP19,MSL3,GPD2,HSF2,IL6ST,IL12A,ITGA7,JAK2,STRN3,PPP5C,MAPK7,PTPRE,RPS20,MAPK12,ZNF821,PREX2,PPP4R3A,ZNF334,CDK19,ZBTB43,LHPP,CRTC1,TMPO,TRIO,VGF,WIPF1,KCNAB1,MPPE1,PHTF2" Drug 5044_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,LGR5,ARRB2,STX16,CFLAR,KYAT1,VCAN,SLITRK5,GIT2,KIAA0753,EXOG,DPH1,OPTN,EGFR,ING4,FER,SHISAL1,IL6ST,INPP5B,MPP2,NDP,PIK3R1,PLCD1,STRN3,POLG,SAMD9,PTPN13,DHX30,SPTAN1,CLASP2,THSD1,SS18,TK2,SSBP2,ZKSCAN5,LMF1,ZBTB14,ZNF711" Drug 3824_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "DOC2A,AMPD3,SEMA7A,SEMA4G,ATP1A3,NRP2,BMP7,FUBP1,SCAPER,MTMR3,STOML1,CRY2,MFAP3L,HIPK3,KAT8,FGFR1,OGA,NEU3,GRIK5,IL12A,ITGA7,LAMA2,MEF2C,OPRL1,PCDH9,PFKFB4,STRN3,ACSS3,GAL3ST4,FBXW7,SNCA,RBM34,DDN,TNS1,NT5M,PHTF2,TIGD6,SENP7" Drug 1677_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,APBB2,SLC4A4,ALDH7A1,SYNJ1,SYNJ2,HAP1,CAMK2B,RAB28,PICK1,BAG4,TBC1D5,RCAN1,ERCC2,ERAP1,ALDH1L1,RAB30,GNG4,HNMT,MBP,KLHDC8A,ZNF821,SUPT20H,FERMT1,PPP4R3A,ZNF423,SPTAN1,ZBTB43,CEP68,STX1A,EXOC7,FBXW11,WSCD1,HEY1,ZKSCAN5,VIPR2,REEP1,GDPD5" Drug 4613_DN Bepridil hydrochloride [74764-40-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,PPFIA3,LGR5,ARNTL,CAMK2G,SPAG9,NFS1,B4GALT6,BAG4,GPRASP1,DBT,TUBD1,RRAGB,ZNF589,SCARA3,ANKFY1,DENND2A,INPP5K,MSL3,GPD2,SHISAL1,NDP,NEK1,NFYA,PTK2,PTPN13,SH3BP2,ASAP3,ELMO2,SMARCD3,LIMCH1,THSD1,SS18,TK2,BEX4,TFIP11,NT5M,FZD3" Drug 2322_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADORA1,ADRA1D,CDC42BPA,APC,APLP1,N4BP2L1,GYG2,LHX2,SULT4A1,AKAP6,PHF14,CYBB,ARHGAP24,SPOCK2,JAKMIP2,HIPK3,FGFR1,CSPG5,FUT9,ALDH1L1,ATXN2L,LIFR,ADAM22,NPTX2,PNMA3,ZDHHC14,ZFHX4,SALL1,STUM,COA1,SPP1,SLC19A3,TNS1,VIPR2,CLIP2,LAT2,PLSCR4,ST7" Drug 4754_DN PNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,MTUS1,LTBP4,AMPD3,FAM131A,ARRB1,MARK4,ADAM15,ST3GAL5,CAMK2G,QKI,AKAP12,PPP6R2,TBC1D5,MFAP3L,HSD17B14,NCALD,KAT8,BAIAP2,PDLIM5,GAD1,GLYR1,ATXN2L,LIG4,LMO2,MEIS1,KITLG,PRKAR1B,PTK2,ZDHHC14,RGS3,FAM214B,ARHGAP26,NXT2,PLCB1,DICER1,THRA,ZKSCAN5" Drug 2738_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,APAF1,PPP4R4,CASK,N4BP2L1,SYNJ1,EPS15L1,QKI,HOMER3,CYBB,DBT,DTNA,E2F5,FCF1,COQ7,NCALD,RRAGB,FHL1,LILRA2,GRB10,LIG4,MAP4,MEF2C,NF1,CCSER2,PILRA,MINDY2,PRKAB2,PTCH1,SLC6A8,TMCC1,UNC5B,TROVE2,CRTC1,ZNF34,CDK20,ZNF24,PCBP4" Drug 5246_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "FZD9,ADORA1,PRX,KSR1,CACNA1I,CYBB,DGKG,HS3ST2,CDON,PHF20L1,PLXNC1,REEP2,KHDRBS3,ALDH1L1,RUNDC3A,STMN2,GRIK5,HLF,AFDN,PDE1C,PDE1B,MAPK7,PTX3,ZMAT4,KLHL11,SALL1,SH3BP2,SLC2A5,KANSL3,SNCA,KIF13A,ZNF415,DOK5,SZT2,TEK,DNAH7,SLC17A7,FAM13C" Drug 3724_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASPHD1,SEMA6A,LTBP4,EPB41L5,CDK10,DNAH17,ADAM23,CFAP410,CAMK2B,FAM149A,RIMS2,CYBB,DTNA,ECM2,EDN1,EPHB1,NCALD,BAIAP2,FYB1,SRCAP,GFER,GSTM5,AP4S1,KCNH2,ADAM22,NF1,PALM,PCDH9,PDE4D,PFKFB4,PTN,CPEB3,ZNF334,SYT5,CHST5,UCHL1,FLRT2,REEP1" Drug 5803_DN Propidium iodide [25535-16-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APBA2,APC,CDC14B,MARCH3,RAB28,NRXN3,ARHGAP24,MFAP3L,SPOCK3,TOM1,HIPK3,FAM13A,AASS,STX2,FGFR1,DENND2A,TMEM8B,SRCAP,PCDH17,ZNF276,IL6ST,MIA2,MT1M,LYRM9,MYO6,NF1,SERPINI1,MAPK7,PTPRN2,FBXW7,FUZ,KDM4B,ZNF423,SYT1,COBL,TBCEL,ZBTB14,KAT6A" Drug 7360_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,NME5,DOC2A,CDC14B,MARK4,BACH1,BAIAP3,KALRN,ARHGAP33,HOMER3,NCOR2,PARD6A,RASGRP2,MTSS1L,EZH1,DLC1,ERAP1,DISC1,GDF9,LPAR4,CNTRL,SPACA9,RNFT2,RASSF8,ATXN2L,ELOVL5,DHX35,MAP4,NF1,PPP2R2B,ZSCAN32,RPS6KA2,TSNAXIP1,TTBK2,CRTC1,SLC44A1,EVI5,TIGD6" Drug 6692_DN Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "RALGAPA1,AP2A2,TRMT9B,APBB2,APOC1,PDE8B,NCOA1,MYRF,SRSF11,DBT,KLHL3,SGSM2,EDNRA,OPTN,ING4,DENND4A,ETV1,ANKMY1,IQCG,GPER1,PCLO,GUCY1B1,NDP,OPA1,GRAMD1C,PTN,SH3TC2,FAM184A,ZDHHC14,TRAPPC13,CHD9,KDM4D,LIMCH1,TROVE2,KIAA1107,TCF4,SIN3B,HIRA" Drug 4640_DN Domperidone maleate; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "KCNAB2,CACNA1I,BAIAP3,CA12,CBFA2T2,SCARB1,ABCG2,CABP1,SLC4A8,CNTNAP2,DZIP3,DTNB,FCF1,NRN1,FGF1,FGFR3,SIGLEC8,GFER,HTATSF1,CNTRL,SOX21,KCNF1,NDP,NNAT,PDE4D,CNTLN,SUPT20H,FRMPD1,TSNAXIP1,SPTAN1,CEP68,ASTN2,RIMBP2,REEP1,DNALI1,EVI5,KCNAB1,EPM2A" Drug 1468_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,CFLAR,KYAT1,FOXN3,SLC4A8,NCOR1,DCAF8,HIPK3,EGFR,FAM49B,PRELID3A,TRAF3IP2,SRCAP,GNG4,GRB10,FAM69A,ITPKB,LIG4,MITF,ADAM22,NRCAM,PDE4A,SLC25A23,WDR25,FERMT1,EPN2,BTBD7,ZNF423,ZBTB43,EXOC7,TRIM2,PLPPR2,VGF,KLC2,EMSY,GDPD5,SEMA3B,PHTF2" Drug 2181_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,CDC42BPA,ARHGDIG,AZGP1,BMP7,SLC16A4,EPS15L1,STOML1,SIPA1L1,PDE4DIP,SPOCK2,OPTN,IQCG,PDLIM5,GATM,ZNF276,KIF5A,PLEC,SLC25A23,PPP2R2B,RGS12,KCTD17,MRAS,RASA3,FERMT1,SNCA,DOK5,HECW1,SPTB,WSCD1,TPM1,FAM155A,FLRT2,LMF1,XRCC4,KCNAB1,FZD3,KAT6A" Drug 4727_UP Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASIC1,ADORA1,BBOX1,SEMA4G,ARRB1,MARK4,ATP2B2,CAMK2B,NECTIN3,CSF1,GSDME,MTSS1L,PRELID3A,DISC1,GPD1,PCLO,SPACA9,ADAMTS13,ATXN2L,MAPT,GPR85,PLTP,PURG,MAPK7,SNRK,ZDHHC14,RFX3,EMID1,SEMA6D,ASAP3,CNKSR2,ARHGAP26,PCDHGB6,AMACR,WIPF1,KCNK12,ITM2C,PLSCR4" Drug 2772_DN (-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,CDC42BPA,ARRB1,BMP7,SCAPER,ARHGEF2,CACNA2D2,SOCS6,PLEKHB1,SIPA1L1,PDE4DIP,KIAA0586,JAKMIP2,PARD6A,EZH1,ZNF589,FGFR1,ALDH1L1,GLYR1,GNG4,KCNN1,LSS,MITF,NPTX2,LRP12,KIF16B,SLC6A8,KIF13A,ARHGAP26,CEP68,PCDHA6,TMEM121,THRA,TK2,CABIN1,REEP1,DNALI1,GDPD5" Drug 1975_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "OGT,KCNAB2,SEMA4G,N4BP2L1,RUNX1T1,TBRG4,FOXN3,EPS15L1,CLCN3,CYBB,GIT2,SPATA2,KIAA0753,DTNA,PHF20L1,RASGRP2,OGA,BTN2A1,HNMT,MAP4,MBD1,MITF,GIT1,MYO5A,SETD4,KCTD15,TMEM231,NEK11,SATB1,SLC11A1,ZKSCAN3,ZSWIM8,MPRIP,DIP2A,MTMR14,KAT6B,PIK3R5,LAMP5" Drug 4822_UP Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYN3,ADD2,FZD9,AP2A2,ANK2,KSR1,CAMK2B,VCAN,CTH,MYEF2,DTNB,AASS,ST3GAL6,FGF1,HPCAL4,PCLO,GRIN2C,KPNA5,MMP16,ADAM22,MSR1,MTRF1L,PURG,MAPK7,RELN,ZSCAN32,PTPRB,RPS6KA2,ZFP2,JMJD6,SYT5,PCDHGA10,TEK,GPR161,FAM155A,MKRN3,GDPD5,JPH3" Drug 5753_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "TRMT9B,SEMA7A,SLC4A4,ATP6V0A1,ADGRB2,BMP7,HAP1,CD86,NRXN3,ABCG2,AKAP7,MYRIP,PDE4DIP,DTNA,EDN1,PLXNC1,SEPT9,POLL,ELOVL5,ITGA7,ITPKA,KCNN1,NTRK2,OPRL1,PDE4D,ENOX1,STUM,DZIP1,HECW1,IQSEC2,DDN,MCF2L,ICAM5,TLR4,PIK3R5,TRIO,AMACR,SENP7" Drug 3365_DN Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,AMH,AMPD3,SEMA7A,APC,FAM131A,RGS20,GYG2,CAMK2G,TAOK2,STOML1,RCHY1,PHF14,ARMCX2,MFAP3L,SGSM2,SUGP2,MBNL2,SPEG,FAM198B,SCARA3,SRCAP,GNG4,KCNJ5,KIT,SMAD1,NF1,CDK18,PLCD1,EMID1,SGK1,SYBU,ANKRD12,DMXL2,SZT2,KCNK12,MAP3K12,DNALI1" Drug 5692_DN Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ALCAM,APOC1,PDE8B,KYAT1,PLAA,VAX2,AKAP7,ARHGEF10,DAPK3,JAKMIP2,MFAP3L,RUSC2,DTNA,STX2,FAM198B,IQCG,MSL3,INPP1,KCNF1,LSS,MAP4,MAPT,MATK,ADAM22,ZNF862,NF1,PLXNB1,SNRK,TMEM104,WDR25,ELOVL2,ZSCAN32,RIPOR1,RAD51D,RGS3,LIMCH1,ASTN2,RPGRIP1L" Drug 2689_DN clozapine; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,MTUS1,FAM131A,CDK10,SLC4A4,MPDZ,CLGN,TAOK2,STOML1,QKI,HOMER3,CREM,SH2B1,CSF1,ARHGAP32,ZNF337,TM9SF4,C2CD2L,EGR3,ERBB2,CSPG5,DISC1,ZNF276,LIG4,SMAD1,MAP4,MEF2C,NF1,CNOT4,PDE4A,RGS3,TCP11L1,MRAS,RASA3,SH3BGR,CLIP2,ZNF711,SPHK2" Drug 7180_UP Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASIC1,APC,APLP1,SCAPER,BAIAP3,CAMK2B,QKI,RCHY1,DAPK3,LYPD1,EGFR,PLXNC1,COQ7,MTSS1L,F8,SEMA4D,ANKFY1,PDLIM5,GFER,TXNL4A,GRB10,LIG4,NF1,PDE1C,ZCWPW1,RGS12,TCP11L1,TRAPPC13,SH3BP2,BTBD7,CLASP2,NXT2,PHLDB1,TRIM2,AP4E1,XRCC4,GDPD5,ST7" Drug 6506_DN Alfadolone acetate [23930-37-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AP2A2,AMPD2,APC,APLP1,SEMA4G,ALDH7A1,KIF1A,GYG2,CA12,MAGI1,CACNA2D2,PLAA,PDE4DIP,DAPK3,CDON,EGFR,COQ7,ANKMY1,SEMA4D,GAD1,KCNH2,IPO5,MAPT,LYRM9,SLC25A23,LRP12,POLG,RAD51D,SH3BP2,AMBRA1,KBTBD4,SPTAN1,SS18,EXOC7,CABIN1,FAM155A,VLDLR,MPPE1" Drug 2494_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AGT,FAM135A,AMPH,BIN1,SEMA7A,PPFIA3,LGR5,PTCH2,KIF1A,KSR1,BMP7,CACNA1G,TAOK2,SLIT2,CREM,HIPK3,MBNL2,RASGRP2,KHDRBS3,GPR162,GPD1,GPD2,SCIN,KCNQ3,LAMA2,NEFM,NF1,NINJ2,CCSER2,SBF1,BTBD3,PHLDB1,WSCD1,RIMBP2,FLRT2,SLC17A7,KCNAB1,FAM13C" Drug 3838_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APBB2,MARK4,MTMR2,GYG2,KYAT1,CBFA2T2,RCBTB2,SOCS6,TAOK2,TPP1,SH2B1,RIMS2,DAPK3,DTNA,EDNRA,MBNL2,EIF4G1,PLEKHA1,ING4,SCML2,FGF12,GFER,GLYR1,HTATSF1,LSS,NEK1,NFYA,OCRL,RETREG1,SNRK,CARF,CCDC25,EPN2,SMARCA4,CDK19,PLCB1,EXOC7,EPM2A" Drug 444_DN clofibrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ARHGDIG,ARRB1,C5,DLGAP1,CHRNA4,PICK1,CPS1,CSNK1E,SEC14L5,KLHL3,RCAN1,DTNA,ECM2,FEM1B,NCALD,FGFR1,IQCG,RUNDC3A,HPGDS,SOX21,MEIS1,MPP2,ADAM22,NOVA1,PRODH,NDUFS7,MTMR10,ZSCAN32,RGS3,ABLIM3,SLC9A5,KBTBD4,POGZ,EXOC7,CDH22,METTL3,WIPF1,ZNF74" Drug 5349_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,AP2A2,APOC1,CDC14B,GYG2,USP2,TAOK2,QKI,SH2B1,SIPA1L1,PDE4DIP,GIT2,F5,ZNF589,ATXN2L,ELOVL5,MAP4,MITF,AFF1,MPP2,GIT1,PLCD1,TMEM104,PTN,NKAIN1,SH3BP2,FAM214B,CXXC4,UNC5B,ZBTB43,PHLDB1,MCF2L,ZNF34,ZKSCAN5,EVI5,GDPD5,HPS4,MPPE1" Drug 2931_DN Tocainide hydrochloride; Down 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,PKP4,MARCH3,SCAPER,ARHGEF1,LHX2,EPS15L1,CSF1R,OSBPL3,DGKG,GSDME,EXOG,PCOLCE2,CSPG5,FYB1,COPS8,GLYR1,GSN,AGFG1,LAMA2,MATK,MEF2C,NEK1,CNOT4,PCDH9,PIK3R1,RET,MCMBP,SLC2A5,ARHGEF40,ZC4H2,STX1A,EXOC7,ZEB1,SYNE1,AP4E1,XRCC4,MAP3K12" Drug 5576_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,LTBP4,APOC1,PPFIA3,EIF4G3,CAMK2B,KRIT1,CBFA2T2,TAOK2,CRY2,SIPA1L1,PPP6R2,STX2,KAT8,ZNF589,BAIAP2,SEMA4D,POLL,GRB10,KCNH2,ZNF862,SETD4,MBOAT7,PRKAR1B,PRPH,RPS6KA2,EPN2,RBM34,ZHX3,ZBTB43,CLSTN2,DIP2A,PHLDB1,SYT1,TRIM2,PARD3,PLPPR2,ZNF184" Drug 7186_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASPHD1,ABHD6,AP2A2,BIN1,EP400,APAF1,BCAS1,ARHGDIG,ARRB2,CDK13,SCAPER,USP2,SRSF11,FOXN3,HOMER3,CREM,NCOR1,ABCG1,DTNA,MRNIP,IP6K2,ATP2C1,SEPT9,IPO5,SETD4,SLC25A23,FBXW7,AMBRA1,ELMO2,ZHX3,UHRF1BP1L,UNC5B,TRIM2,METTL3,RPRM,PLPPR2,VAV1,VGF" Drug 5360_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADCY6,SEMA6A,APBA2,BCAS1,ARHGDIG,BCL7A,CFLAR,ST3GAL5,RCBTB2,FAM189A2,AKAP7,NCOR1,MFAP3L,F5,DLC1,ZNF589,FHL1,SEMA4D,PRELID3A,ZNF276,TXNL4A,MSL3,POLL,MAP4,MATK,ZNF862,NF1,PRKAR1B,MAPK10,FUZ,FNDC3A,DOK5,ZBTB43,TRIM2,NSD1,TMEM121,NR2C2,MPPE1" Drug 7185_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AMPD2,KIF1A,BCL7A,MTMR2,PTBP2,CREM,ABCG1,ZNF337,INTS1,C2CD2L,SUGP2,STX2,GAA,SEPT9,SRCAP,KCNF1,MAP4,SLC25A23,MCMBP,FAM192A,SBF1,AMBRA1,KDM4B,SOX3,ITPRID2,TACC1,ANKRD12,DNMBP,TNS2,TIAM1,BHLHB9,PARD3,CABIN1,RPRM,PLPPR2,VAV1,VGF,XRCC4" Drug 5874_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF1,TRMT9B,APC,RGS9,BMP7,CAMK2B,CACNA2D2,ASIC3,ARHGAP22,TPP1,PICK1,COL9A3,JAKMIP2,MYEF2,PARD6A,HSD17B14,FGF1,FGF12,PRELID3A,TMEM8B,GLYR1,POLL,GPD2,CNTRL,ICA1,ADAM22,ENPP2,PLCD1,MAPK10,KCTD17,NEK11,FBXW7,FNDC3A,PKNOX2,SMARCD3,SMG6,SLC44A1,MPPE1" Drug 1151_DN alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG2,ADD1,C1QTNF3,APC,ARRB1,ZBTB10,N4BP2L1,SYNJ2,TMEM184B,SOCS5,C2CD2L,RHOBTB1,SUGP2,FECH,CGREF1,ERAP1,DISC1,GLYR1,MUM1,AGBL5,SMAD1,SLC11A2,PDE4A,PRKAB2,PTPRO,SBF1,ATXN2,AMBRA1,DZIP1,ARHGEF40,TMCC1,CAMTA2,SEPT8,VPS13A,TCF4,ATP6V0E2,PDSS2,MARCH8" Drug 482_DN celecoxib; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "KDM5D,ADD2,LTBP4,GAS7,ARHGDIG,ARNTL,MPDZ,CD38,KCNAB3,TAOK2,LHX2,PDE4DIP,GIT2,SPATA2,FEM1B,RCAN2,RASGRP2,FCGRT,CAMKK2,NSG1,GAD1,TXNL4A,NCKAP1L,VSIG4,ADAM22,NTRK3,C19orf57,CNNM2,KHDRBS2,GSTCD,FUZ,KBTBD4,SPTB,ANKRD12,CRTC1,TNS1,ZNF142,KCNAB1" Drug 5793_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ASPHD1,ASIC1,FGD2,DDO,PPP4R4,BMP7,MYRF,LDB2,B4GALT6,AKAP5,SH2B1,CRMP1,SPOCK2,PLPPR4,EZH1,SEMA4D,AFF2,GATM,KCNN1,MAPT,NCAM2,WDR25,PTPRB,PID1,ACSS3,SUSD4,EMID1,STUM,RASA3,KIF13A,DOP1A,SP4,NFASC,DMXL2,TPM1,SLC17A7,KCNAB1,DPF3" Drug 5436_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "C1QTNF3,ARHGDIG,MARK4,SYNJ2,SCAPER,BAIAP3,CFAP410,ARHGEF6,ABI3BP,CRY2,SIPA1L1,RUSC2,DTNA,VPS13B,KAT8,FGFR1,IQCG,EFCAB2,INPP5K,GPER1,GRIK5,ELOVL5,IL6ST,MIA2,NF1,LRP12,MBOAT7,NKAIN1,PPP4R3A,EPN2,MAPKBP1,PLCB1,IQCE,PCDHA6,VGF,EMSY,ST7,SENP7" Drug 5100_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "APC,SLC4A4,ALDH7A1,FUBP1,CACNA1A,HIP1R,LARGE1,WHRN,HINFP,BRINP1,EDIL3,HIPK3,MBNL2,RGS17,STX2,FGFR1,SEMA4D,CGREF1,USP19,CNTRL,GIT1,NFIX,STRN3,POLG,PPARA,BEND5,RGS4,MYH15,UNC5B,EXOC7,WSCD1,THRA,OSBP2,ZNF225,NT5M,SLC17A7,AAAS,SENP7" Drug 5643_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,TRMT9B,BIN1,AMT,MARK4,ATP2A2,GYG2,CACNA1I,CBFA2T2,ARHGEF2,UBE2L6,RCBTB2,STOML1,FAM189A2,NRG2,SH2B1,TMCC2,VPS13B,IGSF6,ZNF589,FGF12,BAIAP2,SRCAP,KIF2A,MSI1,ADAM22,PPP3CC,PRKAR1B,FAM184A,ZDHHC14,FAM214B,COA1,DMXL2,CABIN1,PLPPR2,ZNF711,EVI5,SENP7" Drug 2034_DN Josamycin [16846-24-5]; Down 200; 4.8uM; HL60; HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "BRAP,AMPD2,BACH1,RAB29,CARS,ENTPD6,SMARCAL1,CSF1R,DCAF8,ZNF337,ZNF804A,KIAA0753,DTNA,ANKRD46,IGSF6,EZH1,SEC23B,FYN,CRCP,SPIN1,PRRC2B,IRAK3,KTN1,MAN2A2,MARK3,AFF1,NEFH,NFYA,OPA1,MBOAT7,FAM192A,ATXN2,SPART,DIP2A,ANKRD12,CABIN1,TSC2,ZNF189" Drug 2735_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ALK,AMPH,PPFIA4,ADGRB1,GYG2,CFAP410,ARHGAP33,CHRNA4,PICK1,CRYBB1,NCOR2,RIMS2,EXOG,CDON,AASS,ERBB2,DLC1,FHL1,ZNF44,B4GALNT1,SIGLEC8,SEPT9,RUNDC3A,PRUNE2,GRM8,AFDN,MYO6,RASGRF1,KHDRBS2,FRMPD1,CNKSR2,CHST8,TIAM1,TRIO,AMACR,FAM13C,TIGD6,JPH3" Drug 3627_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "SYN3,ADD2,AMPD3,GYG2,CFAP410,CDH2,SULT4A1,VCAN,RIMS2,SPOCK2,GSDME,EGR3,FGF14,FHL1,CAMKK2,KHDRBS3,CSPG5,HPGDS,GNAL,C2orf72,KIF5A,MGAT3,MYO7A,NF1,NLGN3,ELOVL2,PTPRO,ZMAT4,STUM,SH3GL3,DZIP1,PKNOX2,SLC11A1,IZUMO4,HECW1,SYN2,FLRT2,SLC30A4" Drug 2994_DN Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,SRPX,BIN1,CDC42BPA,ANK2,SLC4A4,ATP6V0A1,BACH1,CFLAR,SYNJ1,SCAPER,SGCE,CACNA1A,CACNB4,CLGN,RAB33A,CPS1,SIPA1L1,SLITRK5,PLXNC1,RASGRP2,DLC1,FGFR1,SIGLEC8,GATM,ADAM28,LILRA2,MAP4,TMEM231,MAP6D1,FRMPD1,SPTAN1,NSFL1C,PDLIM2,TRO,KCNK12,REEP1,PARP11" Drug 6791_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AP2A2,APC,PLA2G4C,CA12,SLIT2,QKI,DCAF8,GIT2,SEC16A,DTNA,CELSR3,COQ7,FGFR1,BAIAP2,BTN2A1,RNFT2,MAP4K5,MUM1,DHX35,INPP5B,CNOT4,RETREG1,PTCH1,RAD51D,RNASEL,GSTCD,ROBO1,ZNF821,PDZRN3,SOX3,ZHX3,THSD1,ARC,DNMBP,TRIM2,NDRG4,EPM2A,PHTF2" Drug 6785_UP "Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NME5,SEMA4G,SLC4A4,CFLAR,KSR1,CNTFR,CNTN1,HDAC4,RUSC2,EIF4G2,SCARA3,PDLIM5,GNAO1,GRIK5,ITPKB,KCNJ5,LIG4,ADAM22,NPTX1,PDE4A,LRP12,ELOVL2,TCP11L1,SH3BP2,ASAP3,SLC2A5,PKNOX2,ARHGEF40,MAPKBP1,HECW1,TAL1,HEY1,TK2,TNS1,VLDLR,GDPD5,SLC17A7,ITM2C" Drug 3549_DN Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,PPFIA3,PLA2G4C,BCL7A,CFLAR,ST3GAL5,KYAT1,MAGI1,TMEM184B,AKAP7,ABCG1,CELSR3,FAM49B,INPP5K,STON1,TM6SF1,MEIS2,MIA2,MPP2,ADAM22,NEK1,NF1,NFYA,NRCAM,PPP5C,TRA2B,SH3BP2,PPP4R3A,LIMCH1,ZHX3,SS18,CEP68,PJA1,EXOC7,NPL,ZBTB14,ZNF24,MARCH8" Drug 3300_DN Pilocarpine nitrate [148-72-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADORA2A,AP2A2,AK2,CDK13,KIF1A,CFLAR,SYNJ2,CACNA2D2,SOCS6,CLCN3,FAM189A2,SH2B1,DAPK3,MFAP3L,FGFR1,FHL1,FAM49B,ERAP1,DISC1,RUNDC3A,TXNL4A,CACFD1,DHX35,ICA1,PLEC,PPP5C,RGS12,SH3BP2,LIMCH1,UNC5B,SPTAN1,EXOC7,KIAA0930,TK2,XRCC4,ZBTB14,GDPD5,ST7" Drug 3412_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "DOC2A,AMT,PPFIA3,CDC14B,CDK10,CDK13,SLC2A11,FUBP1,CFAP410,CPS1,TBC1D5,FEM1B,EGFR,EIF4G2,HSD17B14,FLNC,TXNL4A,GLYR1,KCNQ3,KHK,MIA2,LYRM9,PALM,CDK18,PFKFB2,ZDHHC14,RGS3,RGS12,UNC5B,PHLDB1,PLCB1,EXOC7,PIK3R5,RUNDC3B,XRCC4,ZFP37,ZBTB14,PRDM10" Drug 1275_UP Bezafibrate [41859-67-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,EP400,STX16,CAPN3,NFS1,IQCK,RCHY1,CREM,CRMP1,OSBPL3,SIPA1L1,VCAN,RCAN1,FAM13A,COQ7,CDKL3,INPP5K,ZNF276,JAK2,LIG4,LSS,NFYA,SLC11A2,PDE4B,PLTP,CNTLN,ZNF821,GALNT10,ANKRD6,PEX26,SLC11A1,SNCA,TMCC1,SS18,OBSL1,TNS1,TPM1,NPDC1" Drug 7223_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ADD2,AK2,ALK,PRX,SCAPER,CAMK2A,FAM189A2,VAX2,COL9A3,CRYM,RGS6,CNTNAP2,BRINP1,EXOG,DMPK,MBNL2,FGF12,SRCAP,RUNDC3A,GPD2,TDRKH,GPER1,IRF8,KCNH2,KITLG,GIT1,NF1,CLDN11,ZSCAN32,KHDRBS2,RGS4,ZNF821,FAM214B,COA1,LIMCH1,PLCB1,UBE3A,GDPD5" Drug 7351_UP Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABHD6,C1QTNF3,BIN1,ARHGDIG,PDE8B,AZGP1,SYNJ2,RUNX1T1,USP2,MTMR7,ARHGEF6,PICK1,BRINP1,MFAP3L,SUGP2,EZH1,FGFR1,PRELID3A,OGA,GAD1,DISC1,STON1,GRM8,PACRG,MAP4,MGAT3,PALM,CDK18,SLC25A23,ZSCAN32,FAM184A,RGS12,TRAPPC13,FAM214B,CCDC88A,SOX3,VPS13A,SEMA3B" Drug 1641_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "NDRG3,SRPX,APLP1,ATP6V0A1,SCAPER,MTMR3,SRSF11,GPRASP1,KIAA0586,SPOCK2,RCAN1,KAT8,IQCG,FAM49B,OGA,SRCAP,MSL3,LPAR4,DHX35,INPP5B,LSS,MEIS2,KITLG,ADAM22,LRP12,ING3,PPP5C,KCTD17,CCDC25,SPTB,SPART,TRIM2,CHST8,ZKSCAN5,VIPR2,URM1,MPPE1,UBE3B" Drug 984_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "AK2,CDC42BPA,APOC1,MTMR3,SGCE,CAMK2G,CRLF1,RAB28,LYPD1,DTNA,CNNM1,SUGP2,OLFM1,PDLIM5,DISC1,TDRKH,GRIK5,MPP2,PFKFB2,PPP5C,WDR25,FAM184A,RPS20,SH3BP2,KANSL3,SLC11A1,BTBD7,COA1,SNCA,RBM34,ADGRL3,TEK,CABIN1,AMACR,VIPR2,SPHK2,TIGD6,RNF170" Drug 3456_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "ABR,ACTN1,APBB2,CDK13,BMP7,SYNGR3,RAB28,CSNK1E,FAM169A,PPP6R2,TM9SF4,B3GAT3,MFAP3L,LYPD1,MED12,EIF4G2,EIF5,ZNF589,FAM49B,GCNT2,SRCAP,GRB10,INPP5B,LSS,MPP2,GIT1,NF1,OXTR,PLEC,FSD1,APTX,RIPOR1,ZCWPW1,NEK11,CLIP1,TSPYL2,SPART,PLPPR2" Drug 3983_DN Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.44E-04 1.00E+00 6.59E-03 7.42E-02 38 197 "MTUS1,GAS7,CDK10,ARHGAP22,LHX2,CRMP1,HINFP,VCAN,ARHGAP32,NR1D2,CDON,EDN1,MBNL2,VPS26C,GFER,HTATSF1,SLC2A6,MEF2C,MN1,GIT1,TAGLN3,NOVA1,PDE4D,GRAMD1C,ZCWPW1,RGS4,ZNF821,PLCB1,EXOC7,TRIM2,GPR161,THRA,TK2,LMF1,XRCC4,SH3GLB2,EVI5,KCNAB1" Drug CID000008998 meso-erythritol Stitch 7.47E-04 1.00E+00 6.61E-03 7.45E-02 15 54 "ABHD6,AQP6,SLC4A4,CACNA1B,CAPN3,CBS,TNK2,GAA,GPD2,INPP1,MBNL1,SERPINI1,SST,ADHFE1,MCF2L" Drug ctd:C088658 zoledronic acid CTD 7.56E-04 1.00E+00 6.68E-03 7.53E-02 206 1472 "ASIC1,NCKAP5,GALNT16,USP31,UNC5A,KLHL13,CC2D2A,C1QTNF1,BBOX1,SYT13,ANK2,EP400,C6orf89,PKP4,ARNTL,PLA2G4C,MARCH3,RASL11B,ATP1A1,SLC4A4,STX16,SLC2A11,N4BP2L1,BCHE,RGS11,BID,CFLAR,PROM1,SYNJ1,DDR1,CARS,PRC1,CBR1,CBS,LDB2,SLC16A4,CD86,RCBTB2,SRSF11,ARHGAP22,STOML1,ABCG2,RAB26,AKAP7,COL4A5,ABI3BP,FAM171B,CSF1,CTH,ARHGEF4,RIMS2,HDAC9,SNPH,ARHGAP24,DAPK1,LYPD1,RHOBTB1,PARD6A,DLX1,SLC29A4,CPEB2,ARRDC4,ABCC5,EDN1,FEM1B,RASGRP1,FSD1L,OPTN,APH1A,EBI3,PCOLCE2,ENPP6,SIRPB1,ADGRV1,TBC1D16,TUBA1B,TUBB3,DLC1,FCGRT,FDFT1,PPP1R1B,FECH,FGFR3,FHL1,HPCAL4,PCYOX1,TRIM16,AP4B1,FYB1,SDCBP2,MEGF11,DENND2A,SESN1,ADAM28,PCDH17,PPARGC1A,MALT1,PRUNE2,C1QL4,PLCD4,GRM8,FAM107A,RNFT2,ATOH8,HLF,DHX35,IRF8,IGF1,JAK2,KLHL23,KIT,STMN1,NCOA7,LSS,PIK3AP1,MAP2,MATN3,MGAT3,KITLG,MID1,NEFM,NFE2L2,NINJ2,SLC11A2,NRCAM,NTRK2,ZNF827,PALM,PDE4B,PFKFB4,SEMA5B,PIK3C2A,PIK3R1,RETREG1,PLEC,SMOX,PSAT1,PILRA,PPP1R1A,PPP2R2B,PPP3CA,RANBP3L,PRKAB2,PRKACB,PKIA,MAPK3,MAPK10,KLK6,LAMA1,PTH1R,PTK2,STK32A,PTPN13,CASTOR1,PTPRG,RAD17,RAD51D,BEND5,RADX,LGI2,SUGCT,STK32B,LRRK2,KCNIP3,GALNT10,SHC4,ST6GAL1,PREX2,SLC6A8,SLC14A1,SLC22A4,OGDHL,LIMCH1,SNAP25,TMCC1,TRERF1,SPATA7,FNBP1,KDM3A,IZUMO4,ARHGAP26,ATP10B,PBLD,ITPRID2,SSTR1,SS18,NXT2,ST5,RGL1,PHLDB1,SULF2,PLCB1,WSCD1,KIAA0930,CBX5,STXBP4,UGT8,PLEKHH2,PCDH20,ZNF74,NDRG4,TFIP11,PRTFDC1,TUBA1A,ADAMTS9,ADAMTSL3" Drug DB05266 Ibudilast Drug Bank 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "PDE3A,PDE4A,PDE4B,PDE4D" Drug CID000197714 D-22888 Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "ALDH7A1,PDE4A,PDE4B,PDE4D" Drug CID000002184 dihomo-gamma-linolenylethanolamide Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "CNR1,EDN1,PTK2B,TTC7A" Drug CID000132991 pd 151242 Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000257501 2-phenylethenesulfonamide Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000007666 phenethyl bromide Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "ACHE,BCHE,SOCS5,SMC2" Drug CID000025781 monoethylcholine Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "ACHE,BCHE,CACNA2D1,UBC" Drug CID005311425 SB 234551 Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000009209 "1,7-naphthyridine" Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EGFR,PDE4A,PDE4B,PDE4D" Drug CID000129432 Et-(16-21) Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID004574540 L015040 Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000077338 fenclorim Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "KYAT1,GCK,GLUL,GSTCD" Drug CID000469585 CBVMP Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "AMPD2,AMPD3,POLG,TK2" Drug CID000023941 H2PO Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "ABHD6,GFER,GSN,NBL1" Drug CID000197302 Be 18257a Stitch 7.58E-04 1.00E+00 6.68E-03 7.53E-02 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000005514 T2755 Stitch 7.72E-04 1.00E+00 6.80E-03 7.66E-02 18 71 "ASIC1,CA4,CA12,CACNA2D1,ASIC3,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNH2,NPY,PPARA,PTCH1,SCN7A,CA14" Drug 7490_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.72E-04 1.00E+00 6.80E-03 7.66E-02 36 184 "AK2,CDK13,PDE8B,SLC4A4,SYNJ2,CA12,CBFA2T2,CHN2,PLEKHB1,GREB1,TMCC2,RASGRP1,EGR3,PIPOX,FER,TRAF3IP2,RASSF8,SYNPO,INPP5B,JAK2,KIT,NKAIN1,RET,GSTCD,FBXW7,MAP6D1,SGK1,SYBU,COA1,LIMCH1,KDM4B,SOX15,ARC,WSCD1,SLC44A1,UCHL1" Drug 4369_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-04 1.00E+00 6.80E-03 7.66E-02 36 184 "NDRG2,FZD9,TRMT9B,PLA2G4C,MARK4,CALB1,CAMK2B,USP2,CNTN1,CRYM,DTNA,EDN1,EGR3,REEP2,DLC1,GAD1,ALDH1L1,GRM8,KCNN2,PCBP3,PGAM2,PLCD1,MINDY2,RFX2,SGK1,HECW1,PEG10,ZC3H13,CDK19,ATP10B,TBCEL,TNS1,UGT8,VLDLR,LAT2,SLC30A3" Drug ctd:D008748 Methylcholanthrene CTD 7.75E-04 1.00E+00 6.83E-03 7.70E-02 151 1038 "ASIC1,ABHD6,AS3MT,RNF157,ADORA2A,KCTD16,SPARCL1,ALCAM,ANK2,SEMA7A,ARMC12,APAF1,APOC1,APOC2,CASK,LINC00173,RASL11B,EIF4G3,CACNA1G,CA8,CA12,CACNA1B,CALB2,CALM1,CAMK2B,CAST,PRC1,CBR1,CBS,CDH2,DCLK1,MAGI1,SRSF11,MS4A7,ARHGAP22,SLIT2,CLTC,ABCG2,CNTN1,ABI3BP,COX4I1,ZNF521,RBM39,CST3,GREB1,PPP6R2,KATNAL2,CENPL,DAPK1,DBN1,ELMSAN1,HEPH,ELMO1,MFAP3L,FBXL5,GSDME,RHOBTB1,DTNA,EGR3,KCTD3,TNK2,PCOLCE2,CALCRL,ETV1,NRN1,ACSL4,FGF1,OLFM1,FGFR1,BAIAP2,POLK,SYNCRIP,RGPD5,NELFCD,PDLIM5,TRIM16,STAU2,MPP6,FYN,GABRA3,GALNT15,ZNF234,SRRM4,GHR,GRIK4,GRIK5,RABL2A,MUM1,HBA1,HNMT,IGFBPL1,IDH3A,RBPJ,IL12A,ITGA7,JAK2,STMN1,PAXBP1,MATN2,MBNL1,CHIC1,KITLG,MID1,MYO7A,NFE2L2,ALDH1L2,NFYA,NPTX1,P2RX7,P2RY1,PDCD2,PDE1B,ENPP2,ABCB1,PIK3R1,PCDH18,MAPKAP1,POLR2F,PPARA,PRKAB2,BCAS3,WBP1L,PTK2,SPDL1,PTN,RGS3,ROBO1,RTN1,RXRA,RYR3,MAPK12,SEMA6D,SHC4,PKNOX2,TRERF1,POGZ,MESP1,SS18,NXT2,DNAJC9,PCDHB9,FRYL,SIK3,VWCE,ZMAT3,SLC44A1,PIK3R5,TRPM2,HSPBP1,TTC3,NDRG4" Drug ctd:C054133 casticin CTD 7.80E-04 1.00E+00 6.87E-03 7.74E-02 46 252 "AXIN2,SPARCL1,APAF1,ARNTL,HCN2,BID,CALM1,QKI,CRHBP,RAB39B,ABCC5,EGFR,EIF5,IRAK4,GPHN,SYNCRIP,FOXO3,PPARGC1A,NKD1,IL12A,NME9,KCNH2,SMAD1,MARK3,MBP,MEST,MYO7A,P2RX7,GPR85,PMP22,EPB41L4B,PTK2,PTPRD,ZSCAN2,ZFHX4,TRA2B,FBXO11,RCOR3,LIMCH1,PCDHA1,THRA,TLR4,METTL3,TRIO,VLDLR,ZNF711" Drug DB01244 Bepridil Drug Bank 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "ATP1A1,CACNA1A,CALM1,CACNA2D2,PDE1B" Drug CID000060754 gadodiamide Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "WDR20,CASP8AP2,NACA,MRAS,SLC14A1" Drug CID006440491 neoxaline Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "ACHE,CBS,IL6ST,PKM,PKIA" Drug CID000083651 I50 - 9 Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "EGFR,ERBB4,MAPK3,MAPK9,MAPK10" Drug CID003086590 w 77 Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "KDM5D,NCALD,ABCB1,GSTCD,VSNL1" Drug DB00651 Dyphylline Drug Bank 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "ADORA1,ADORA2A,PDE4A,PDE4B,PDE4D" Drug CID005362399 bemoradan Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "ALDH7A1,ITGAM,PDE3A,PDE4B,PDE4D" Drug CID000003073 diisopropyl methylphosphonate Stitch 7.84E-04 1.00E+00 6.89E-03 7.77E-02 5 8 "ACHE,BCHE,DMTF1,PIK3C2A,SPP1" Drug 4458_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.92E-04 1.00E+00 6.97E-03 7.85E-02 34 171 "ADRB2,ARNTL,MARK4,ST3GAL5,CHN2,STOML1,ABCG1,PDE4DIP,CTH,JAKMIP2,PLPPR4,EDNRA,BAIAP2,FYN,CYP46A1,RUNDC3A,GUCY1B1,LSS,MAP2,PCDH9,SERPINI1,RETREG1,PRPH,RGS4,SH3GL3,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,RUNDC3B,SLC30A3,SLC17A7" Drug 2634_DN Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ABHD6,BCL7A,CFLAR,ST3GAL5,SLC25A14,KRIT1,PLEKHB1,DZIP3,DCAF8,DTNA,EIF5,PRKAG2,SMC2,PDLIM5,FAM49B,MPP6,MSL3,GNG4,HNMT,MAP4,MBD1,NEK1,NF1,CEP97,ROBO1,SGK1,SIRT2,SMARCC2,SS18,SUPT5H,TACC1,IQCE,DOCK9,XRCC4,ZNF24,EMSY,MPPE1" Drug 5917_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ADORA1,BEGAIN,KCNAB2,PRX,MARK4,ATP6V0A1,RGS9,CACNA2D1,SEPT7,CHRNA4,PICK1,CNTN1,DCAF4,RUSC2,TMCC2,DTNB,EDN3,MBNL2,EGR3,ING4,FYN,ADAMTS13,ELOVL5,TJAP1,ADAM22,PLCB2,MINDY2,PTPRE,KLHDC8A,STUM,PREX2,NMNAT2,HECW1,DOCK9,OSBP2,SLC17A7,UBE3B" Drug 5581_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ADORA2A,C1QTNF1,ALK,AMT,ANK2,APAF1,SEMA4G,CDK13,NRG2,CNTNAP2,GSDME,DPH1,DTNB,EDNRA,ING4,KHDRBS3,TMEM8B,GLYR1,STON1,GPER1,GRM8,TJAP1,KCNN1,LYRM9,SERPINI1,LRP12,TRIM68,RNASEL,SH3GL3,SLC6A11,SLC11A1,CDK19,ARHGEF9,TK2,R3HDM1,TRIO,PRDM10" Drug 991_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ABHD6,AP2A2,NCOA1,ADAM15,PLAA,QKI,ABCG1,GIT2,SGSM2,CELSR3,EGR3,STX2,KAT8,FGFR3,EVL,POMT1,SYT17,FERMT2,GPR37,GRB10,SLC2A6,PCDH9,PIK3R1,RETREG1,PMP22,PKIA,RIPOR1,RAD51D,SEC14L1,ZFP30,ZSWIM8,CAMTA2,TACC1,TBL1X,PARD3,UBTF,HPS4" Drug 1813_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "APAF1,FAM131A,MPDZ,CFLAR,SOCS6,ARHGAP22,PDE4DIP,CTH,PPP6R2,PHC2,FCF1,ING4,FGF1,FHL1,PCYOX1,DENND2A,HAS2,IFI16,IL6ST,MATN3,MBNL1,OGG1,PLCD1,SH3TC2,SHMT2,CCDC88A,LHPP,SS18,TRIM2,SZT2,TNS2,TMPO,TRIO,ZNF23,EVI5,AAAS,DPF3" Drug 2857_DN Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "CDC42BPA,APBB2,EIF4G3,ATP6V0A1,SOCS6,B4GALT6,C2CD2,CREM,MED12,DTNA,DNAJB6,MBNL2,RGS17,VPS13B,DENND4A,BAIAP2,MALT1,GLYR1,NEK1,NRCAM,C1orf109,ZCWPW1,ZDHHC14,RXRA,PPM1E,KDM4B,JMJD6,ARHGEF9,MCF2L,IQCE,TBL1X,NSD1,PARD3,LMF1,ZBTB14,ZIC1,ACTR3B" Drug 7549_DN CP-944629 [668990-94-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "MARCH3,FUBP1,MTMR2,SPAG9,ARHGEF2,QKI,HOMER3,PHF14,SPOCK3,RCAN1,EDIL3,EGFR,RGS17,ETV1,VPS26C,FGFR1,ANKFY1,DENND2A,ERAP1,GLYR1,ATXN2L,INPP5B,MBNL1,MYO6,NEK11,CLIP1,ZFP30,NXT2,ZEB1,DOCK9,CLDND1,XRCC4,ZNF711,HPS4,EPM2A,FZD3,RNF146" Drug 6498_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "AK2,C1QTNF1,APOC1,ATP1A3,GYG2,CACNB4,PLEKHB1,TPP1,SLC4A8,SNCAIP,GREB1,RCAN1,EGR3,C3orf18,FER,FGFR1,PDLIM5,TPPP3,GALC,PCDH17,TXNL4A,GPR75,HMGCR,MBD1,PURG,POU6F1,PPP5C,RGS3,ARC,TRIM2,DNAH7,SLC44A1,TRIO,TRPM2,HIRA,SLC30A3,EVI5" Drug 5567_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "PPFIA3,MARK4,CBFA2T2,SCARB1,SOCS6,TAOK2,CRY2,PHF20L1,EIF5,FGFR1,MALT1,TXNL4A,RAB30,MAP4K5,ATXN2L,IL6ST,JAK2,KCNH2,KHK,MPP2,SMIM7,ZDHHC14,RGS3,FBXW7,SH3BP2,MAPKBP1,ZHX3,TROVE2,STX1A,JMJD6,WSCD1,TMEM121,PARD3,PLPPR2,EVI5,GDPD5,ACTR3B" Drug 6555_UP Prostaglandin E1; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ADGRB2,SYNJ1,ST3GAL5,HAP1,CBS,CCNT1,CREM,AKAP12,CSNK1E,CTH,GIT2,PITPNC1,MRNIP,ETV1,FYB1,INPP5K,GLYR1,KCNN1,MAPT,MIA2,MX1,NF1,NTRK2,PIK3R1,SMOX,PRKAR1B,CNNM2,SNRK,FBXW7,ZFP30,ASAP3,UNC5B,ARHGAP26,ZBTB43,TBL1X,TCF4,NT5M" Drug 5964_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "ABR,ASPHD1,AP2A2,ALK,CA12,CAMK2B,SCARB1,FOXN3,VAX2,HOMER3,GREB1,DBN1,C2CD2L,DTNA,RASGRP1,EGR3,F5,GAD1,SRCAP,IL6ST,JAK2,KCNF1,KHK,LIG4,MMP17,PRKAR1B,ELOVL2,RET,KCTD17,RNASEL,FBXW7,MAP6D1,NUBPL,SS18,ARC,LAT2,SLC30A3" Drug 2850_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "SEMA6A,ALCAM,EPB41L5,ATP6V0A1,TAOK2,ARMC8,AKAP12,DCAF8,EIF5,VPS13B,DENND4A,ACSL4,FHL1,GALC,TXNL4A,GLYR1,RAB30,LSS,MAP4,MPP2,GIT1,NF1,NLE1,ZDHHC14,RET,RGS3,ATXN2,SUPT20H,SGK1,FNDC3A,SS18,ARC,TNS2,TMPO,PLPPR2,REEP1,PHTF2" Drug 6008_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "GAS7,CDK10,SCAPER,CACNA2D2,SOCS6,TPP1,CNTFR,SMARCAL1,NECTIN3,INTS1,DAPK1,EDNRA,TNK2,COQ7,RASGRP2,NCALD,ZNF391,FAM49B,FYN,ALDH1L1,STMN2,ATXN2L,KCNJ5,MSI1,PDE4B,GPR85,KHDRBS2,TCP11L1,SBF1,SEC14L1,SLC2A5,SMARCD3,KDM4C,TRIM2,ZNF34,VLDLR,GJC2" Drug 7305_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "TRMT9B,ALDH7A1,CAPN3,HIP1R,HOMER3,CSF1,VCAN,ARHGEF4,HDAC9,MTSS1L,EZH1,DENND2A,GAD1,POLL,GNG4,GUCY1B1,IFI16,SCIN,FAM69A,MX1,PALM,FA2H,PRKAR1B,SAMD9,PTPRE,RGS4,KCTD17,TMCC1,THSD1,SS18,KIAA1107,DOCK9,SLC35G2,TIAM1,TK2,WIPF1,ST7" Drug 6744_UP Metergoline [17692-51-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.98E-04 1.00E+00 7.00E-03 7.89E-02 37 191 "LTBP4,APBB2,GAS7,SLC4A4,CFAP410,CALB1,SYNGR3,CLTB,HAPLN1,AATK,CTH,EDIL3,HIPK3,COQ7,F5,CORO2B,TRMO,GATM,ELOVL5,KITLG,ADAM22,MT1M,NCAM2,RETREG1,FA2H,ELOVL2,PTPRH,RGS4,RGS12,ZFP30,CNKSR2,TROVE2,SYN2,SYT5,TK2,R3HDM1,KCNAB1" Drug CID000000106 pSer Stitch 8.18E-04 1.00E+00 7.02E-03 7.90E-02 27 126 "NFS1,SEPT7,CNOT8,BOC,IP6K1,ACOT8,EEF1D,F8,PDLIM5,SDCBP2,INPP5K,CBX1,GRM2,GRM8,HP,MAP4,MYT1,PSAT1,PTH1R,PCMTD2,SHMT2,SPP1,JMJD6,SUPT5H,SYT1,CBX5,BHLHB9" Drug CID000086222 Spotlight Stitch 8.18E-04 1.00E+00 7.02E-03 7.90E-02 27 126 "APAF1,APC,CACNA1A,CACNA1B,CNR1,HDAC9,DBN1,DYNC1I1,ENO2,PPP1R1B,PPARGC1A,TCERG1,PACSIN2,HP,IGF1,OGG1,ABCB1,QDPR,CEP97,RGS3,FBXW7,ATXN7,FOXRED1,SNCA,SP4,PRTFDC1,JPH3" Drug CID003645780 RS)-2-chloro-5-hydroxyphenylglycine Stitch 8.21E-04 1.00E+00 7.02E-03 7.90E-02 9 24 "ADORA1,ADORA2A,CNR1,GRIN2C,GRIN2D,GRM2,GRM8,LIMS1,RELN" Drug 6481_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADD2,ALK,BEGAIN,PPFIA3,ALDH7A1,N4BP2L1,PROM1,SCAPER,MTMR3,SGCE,CACNA1I,CA4,CACNA2D1,WHRN,COL9A3,DCAF4,RASGRP2,KAT8,FER,ALDH1L1,PCDH17,SPACA9,GRIK5,CACFD1,GRM8,SYNPO,DHX35,ICA1,PALM,PLCD1,LRP12,FRMPD1,ST6GAL1,CNKSR2,PKNOX2,UGT8,WIPF1,SLC17A7" Drug 1629_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,CDC42BPA,GAS7,MARK4,CAMK2G,VAX2,HOMER3,RIMS2,RCAN1,DTNA,EXTL2,KAT8,FLNC,TRMO,GNG4,GRIK5,HNMT,LMO2,MID1,MKLN1,NTRK2,PCDH9,PDPK1,PLXNB1,GSTCD,TCP11L1,ZNF821,AMBRA1,FBXO11,PREX2,PEX26,SNCA,PCDHGA10,CRTC1,BEX4,KAT6B,VGF,MAP3K12" Drug 3051_UP Bemegride [64-65-3]; Up 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,ADCY6,MTUS1,SEMA4G,ARHGDIG,CFAP410,MAGI1,CACNA2D2,LHX2,RAB26,USP6NL,DMD,EDN3,LRRC17,FHL1,ZNF276,C2orf72,IL6ST,KIF5A,KIFC3,PCSK5,PDE1C,DCHS2,CNNM2,BCAS3,GAL3ST4,KCTD17,SEMA6D,SYBU,SLC11A1,DOK5,PEG10,NFASC,ATP10B,PHF24,AP4E1,ICAM5,MAP3K12" Drug 3219_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,DNAH17,CACNA1G,BAIAP3,HIP1R,CDH2,NDST3,CNTFR,HDAC9,ZNF804A,EDNRA,CDKL3,FGFR1,FHL1,PRELID3A,NSG1,FUT9,ATXN2L,HLF,SYNPO,HNMT,MYCN,NPTX1,NTRK2,MAPK7,ELOVL2,RIPOR1,CCDC40,RGS12,TCP11L1,SH3BP2,FAIM2,SYT5,RPGRIP1L,TRPM2,VLDLR,FAM13C,PHTF2" Drug 4805_DN Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,AP2A2,LTBP4,BIN1,ARRB2,PDE8B,MARK4,CFLAR,SCAPER,HAP1,LHX2,CREM,SH2B1,DCAF8,EDNRA,PLXNC1,FECH,FGFR1,AHDC1,DHX35,MAP4,FSD1,ZCWPW1,MAPK12,ABLIM3,SMARCA4,KIF13A,IQSEC2,KANK1,ARC,PCDHGA10,ZNF34,TSN,UBTF,LMF1,EVI5,HPS4,SEMA3B" Drug 4021_DN Nadolol [42200-33-9]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,ADGRF5,PDE8B,DNAH17,KIF1A,CACNA2D2,FOXN3,ARHGAP22,RAB26,WHRN,COL9A3,CSF1,ARHGEF10,VCAN,PARD6A,AASS,AFF2,ZNF44,AHDC1,USP19,MSL3,POLL,GPD2,GRM8,TJAP1,ITPKA,MX1,CLDN11,FSD1,PRKAR1B,PTN,KHDRBS2,FRMPD1,FUZ,ARHGAP26,ARC,ASTN2,ADGRL3" Drug 6248_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,SYT13,BIN1,AMT,SEMA4G,SLC4A4,CFLAR,MTMR2,HAP1,CAMK2B,CRLF1,CNTNAP2,MYEF2,TMCC2,AASS,ING4,EFCAB2,USP19,ADAMTS13,ATXN2L,MAP4,NPR2,PPP5C,CEP97,SGK1,FAIM2,SPTAN1,EXOC7,PCDHA5,THRA,UBE3A,VIPR2,ZFP37,SPHK2,NT5M,EVI5,KCNAB1,FAM13C" Drug 2150_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "C3orf14,APAF1,APBB2,APOC1,ARRB1,ZBTB10,SYNJ2,THSD7A,CREM,ABCG1,MFAP3L,DTNA,CNNM1,FAM13A,VPS13B,DLC1,FGFR1,GALC,ALDH1L1,ZNF276,MAP4,MIA2,ZNF862,NEK1,PDE4B,CEP41,RIPOR1,ZNF493,FBXW7,MAP6D1,HSPA4L,SEPT8,CEP68,TBCEL,KAT6B,RUNDC3B,NT5M,EVI5" Drug 6042_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASPHD1,BRAP,ADRA1D,FAM131A,ATP2A2,KSR1,USP2,FOXN3,WHRN,CRY2,RASSF2,JAKMIP2,EDNRA,CELSR3,MBNL2,PLXNC1,PDLIM5,B4GALNT1,RAB30,IL6R,KCNF1,KCNH2,KPNA5,MAP4,MMP16,MSI1,NNAT,CCDC25,RPS6KA2,SEC14L1,SH3BP2,ASAP3,PHLDB1,PLCB1,EXOC7,TNS1,WIPF1,EVI5" Drug 168_UP sulindac; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBB2,ARRB1,PDE8B,MTMR3,AP4M1,TBRG4,SOCS6,CHN2,TAOK2,PCYT1B,ARHGEF10,C2CD2L,OPTN,MBNL2,EPB41L2,NEU3,RUNDC3A,GRM8,BTN2A1,MBD1,MIA2,NTRK3,SLC25A23,PMP22,CYBC1,TTC13,RAD51D,RGS3,SEMA6D,ASAP3,FUZ,ABLIM3,SIRT2,DOK5,EXOC7,TRIO,SLC17A7,SMIM8" Drug 6957_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASPHD1,DOC2A,AMPD3,MAP4K3,APLP1,CDC14B,SYNJ2,CALB2,ARHGEF2,MAGI1,PLEKHB1,EPS15L1,PLAA,HOMER3,CREM,PDE4DIP,EGR3,PLEKHA1,EFCAB2,SIGLEC8,INPP5K,MEIS1,MITF,MSI1,NFYA,RETREG1,TCP11L1,CXXC4,KDM4B,SOX3,SPART,ARHGEF9,ASTN2,EXOC7,CRTC1,SIK3,TMPO,REEP1" Drug 6254_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BIN1,GAS7,ADAM23,GYG2,STOML1,QKI,WHRN,DOCK4,RIPOR2,LYPD1,DTNA,TOM1,EDNRB,COQ7,SPEG,KAT8,FHL1,AHDC1,INPP5B,ADAM22,NPR2,PPP5C,CNNM2,NKAIN1,ZCWPW1,SH3BP2,CNKSR2,SLC9A5,SNCA,ZNF423,SPART,PHLDB1,ARHGEF9,PLCB1,ADGRL3,TBCEL,KIAA0930,SPHK2" Drug 2054_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ACTN1,ADCY6,ARRB2,SPAG9,AP4M1,LHX2,AKAP7,HINFP,ARHGEF4,FGFR1,BAIAP2,TRMO,CRCP,PCLO,IL6ST,SMAD1,POLG,PRKAB2,BCAS3,TMEM260,SBF1,SEC14L1,SH3BP2,PEX26,SPTAN1,CEP68,TTBK2,VPS13A,TBL1X,GPR161,TMPO,HIRA,NPDC1,XRCC4,ZNF24,EVI5,SMIM8,RNF170" Drug 4700_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,SYT13,AMPD3,KCNAB2,PDE8B,BAIAP3,LDLRAD4,CALB1,CAMK2B,CACNA2D2,QKI,CTH,CYBB,RASSF2,C2CD2L,FHL1,AFF2,FUT9,GAD1,GALC,DISC1,TDRKH,MEF2C,KITLG,NFYA,NTRK2,TREM2,CDK18,MAPK10,RPS6KA2,RASA3,PREX2,CCDC88A,DMXL2,PCDHA6,XRCC4,ZFP37,ZNF24" Drug 5389_DN Ganciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,ASPHD1,APLP1,SCARB1,SOCS6,SH2B1,CRY2,NCOR1,CNNM1,IRAK4,ZNF589,FHL1,IQCG,MPP6,RUNDC3A,GNG4,SPACA9,GRIK5,ATXN2L,HNMT,INPP5B,MAP4,MPP2,PLXNB1,PRKAR1B,PRPH,TMEM104,ZFP30,EPN2,ZSWIM8,CEP68,PLCB1,CABIN1,PLPPR2,EMSY,GDPD5,HPS4,RNF170" Drug 7327_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG3,AK2,KIF1A,RAB29,CHN2,PLEKHB1,B4GALT6,NCOR2,MFAP3L,EIF5,ING4,FYB1,SIGLEC8,LPAR4,CACFD1,INPP1,MGAT3,MMP16,MSI1,LYRM9,NF1,CNOT4,NOVA2,NLE1,SAMD9,ZSCAN32,RGS12,SBF1,ASAP3,ABLIM3,SMARCD3,RBM34,TSNAXIP1,ERC1,TROVE2,DOCK9,THRA,EVI5" Drug 2437_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADD2,ARRB1,CFAP410,CA12,THSD7A,CLCN3,CSF1,DAPK1,DBT,E2F5,EIF1,MTSS1L,ANKMY1,PTK2B,DLC1,PRKAG2,AFF2,TRAF3IP2,CPLX2,GFER,USP19,RUNDC3A,GLI2,MX1,WDR25,PTCH1,PTPN13,CRTAC1,SH3BGR,FERMT1,DOK5,MTCL1,RPGRIP1L,TNS1,RPRM,SLC17A7,KCNAB1,ST7" Drug 4496_UP Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AMPD3,SEMA7A,PPP4R4,CDK13,ATP1A3,ATP2B2,GYG2,CHRNA4,STOML1,LRIG1,PDE4DIP,SPOCK2,C2CD2L,CHRDL1,DMPK,DUSP9,PRELID3A,GATM,PRUNE2,CNTRL,ADAMTS13,IL6ST,FXYD7,VPS13C,PTPRH,TMEM231,RGS4,KIRREL1,KCNIP1,DOK5,EXOC7,TBL1X,SMG6,PCDHGA10,AP4E1,HIRA,WIPF1,SPHK2" Drug 1800_DN Allantoin [97-59-6]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADGRF5,BIN1,APOC1,SEMA4G,MARK4,CFLAR,CA12,DAPK3,KIAA0753,PARD6A,TMCC2,FEM1B,SCML2,BAIAP2,INPP5K,SRCAP,DIDO1,DHX35,SHISAL1,MITF,MX1,SLC25A23,FA2H,MCMBP,ASAP3,ANKRD6,LIMS2,ELOVL4,EXOC7,TRIM2,NSD1,CABIN1,FAM155A,UBTF,LMF1,XRCC4,HPS4,MPPE1" Drug 7307_DN Triamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBA2,PPFIA3,ST3GAL5,SCARB1,CNOT8,NRXN3,QKI,NRG2,NCOR1,PDE4DIP,SLITRK5,PPP6R2,TBC1D5,DAPK3,ARMCX2,SPATA2,PDLIM5,GLI2,GLYR1,CNTRL,HMGCR,MBD1,NFIX,SLC11A2,PDPK1,TMEM104,ELOVL2,MCMBP,KBTBD4,PDZD2,SPART,CLASP2,ST5,TMPO,HIRA,MAP3K12,NAV3,FZD3" Drug 6603_DN Reserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PPFIA3,CACNA1A,CBFA2T2,SCARB1,ARHGEF2,TPP1,HOMER3,MFAP3L,EXOG,DMPK,CDON,TOM1,FAM13A,MBNL2,PDLIM5,FYN,MAN1B1,KPNA5,IPO5,MAPT,LYRM9,PLEC,MAPK7,GRAMD1C,FUZ,SLC4A3,SLC6A8,SMARCA4,ZBTB43,DDN,SMG6,RPGRIP1L,SZT2,PARD3,CABIN1,NDRG4,FTSJ1,NT5M" Drug 5422_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SPARCL1,LTBP4,MPDZ,CFLAR,ST3GAL5,SLC16A4,ARHGEF1,ARHGAP33,CLGN,ABI3BP,USP6NL,ELMO1,DTNA,EDNRA,COQ7,DENND4A,FHL1,AGAP2,TMEM8B,ALDH1L1,GRB10,KCNH2,KCNN1,KIT,TAGLN3,MYO7A,NTRK2,POLG,FAT4,RFX2,SATB1,FBXO11,SLC2A5,SLC11A1,RGL1,ANKRD12,DMXL2,DNALI1" Drug 5672_UP Tyloxapol [25301-02-4]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BEGAIN,CDK13,RGS11,MTMR7,DCLK1,DLGAP2,DLGAP1,AKAP6,NCOR2,AATK,BRINP1,DBN1,EGFR,NRN1,PTK2B,FYB1,SIGLEC8,GNAL,LPAR4,MCHR1,GRIK5,GRM8,GSN,KCNJ5,LAMA2,MEF2C,PDE4D,GDPD2,RNASE1,TCP11L1,ARHGEF40,RBM34,IQSEC2,SAMSN1,TCF4,TRIM2,R3HDM1,PARP11" Drug 5420_DN Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,APBB2,ALDH7A1,CFAP410,AKAP7,CRY2,GPRASP1,KIAA0586,DBN1,MFAP3L,IRAK4,KAT8,ZNF589,RUNDC3A,ZNF276,TXNL4A,MSL3,GPD2,GPER1,SPACA9,HNMT,DHX35,KHK,LSS,MMP16,NPR2,ELOVL2,NKAIN1,GTDC1,RGS12,RNASEL,KIF13A,PHLDB1,PLCB1,TK2,VGF,ZNF74,PHTF2" Drug 7266_UP THIP Hydrochloride; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,ASIC1,ADCY6,SHROOM2,FOXN3,RAB28,STOML1,DZIP3,LYPD1,EIF4G2,RGS17,TMEM8B,SRCAP,CNTRL,INPP5B,JAK2,KCNN1,NFYA,NOVA2,SLC11A2,POLG,WDR25,ZSCAN32,PTPRE,RGS4,ZFP2,FAM214B,SMARCD3,MYH15,SYT1,KIAA1107,FBXW11,TRIM2,TK2,CABIN1,SSBP2,ZNF189,EPM2A" Drug 3987_DN "Azathymine, 6 [932-53-6]; Down 200; 31.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADRA1D,MTUS1,DNAH17,KIF1A,RAB26,HOMER3,WHRN,CREM,HAPLN1,HINFP,ARHGEF10,CSNK1E,PARD6A,CDON,MBNL2,AASS,IRAK4,MRNIP,MTSS1L,FAM49B,SYT17,TDRKH,GRM8,MAPT,MEF2C,TAGLN3,GRAMD1C,FRMPD1,ASAP3,PEX26,TSNAXIP1,ARHGAP26,ELOVL4,TIAM1,TRIO,OSBP2,KCNAB1,TIGD6" Drug 2887_DN Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AMPD3,SEMA4G,NUMB,CAMK2G,ARHGEF1,ARHGEF2,ABI3BP,CRY2,NCOR1,PHF14,DCAF4,MFAP3L,LYPD1,INPP1,INPP5B,KCNH2,MAP4,MIA2,MMP16,GIT1,LYRM9,NEK1,NF1,PMP22,PPP5C,ZSCAN2,SBF1,SH3BP2,ASAP3,SLC6A8,CXXC4,RBM34,ERC1,UNC5B,SPTAN1,TTBK2,KIAA1107,PLPPR2" Drug 5490_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AK2,C1QTNF3,SRPX,APOC1,KIF1A,C5,RAB28,VAX2,QKI,AKAP7,SLC4A8,BAG4,ZNF337,C2CD2L,SGSM2,MAMLD1,CNNM1,ENO2,PCLO,TM6SF1,NF1,PPP5C,RGS12,GSTCD,SBF1,PEX26,LIMCH1,MAPKBP1,CDK19,SPART,VPS13A,TIAM1,NPL,UBTF,PLPPR2,ZNF74,EPM2A,RNF146" Drug 7353_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,BIN1,APBA2,ARHGDIG,STX16,SYNJ2,CALB2,CAMK2G,SCARB1,HOMER3,FAM169A,GIT2,EXOG,DTNA,MRNIP,ERCC2,EZH1,AFF2,SRCAP,MALT1,TXNL4A,CACFD1,ELOVL5,MAP4,ADAM22,NF1,RETREG2,PPP5C,ZSCAN32,PTPRE,RGS12,ZNF821,LIMCH1,RBM34,SYT5,UBE3A,ZBTB14,EVI5" Drug 3022_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADGRB1,KSR1,SYNJ2,CAMK2G,SCARB1,CLGN,SOCS6,CHRNA4,TAOK2,LHX2,RAB33A,ABCG2,COL9A3,CPS1,CREM,PDE4DIP,RUBCN,AASS,VPS13B,RASGRP2,DLC1,ADAM28,PRUNE2,AP4S1,MAPT,NLE1,POU6F1,MAP6D1,SEC14L1,MYH15,SNAP25,WSCD1,DOCK9,TPM1,TRO,KCNK12,SH3GLB2,JPH3" Drug 2328_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,SPARCL1,APAF1,APC,DNAH17,RASL11B,GYG2,KALRN,CDH2,ARHGAP33,CLGN,CPS1,DTNA,OLFM1,FGFR1,BAIAP2,TPK1,GPR162,POLL,IRAK3,ICA1,ITGAM,KCNJ5,MAP4,ADAM22,MYT1,NNAT,PLTP,MTRF1L,APTX,C1orf54,SPART,ATP10B,KIAA0930,SZT2,OBSL1,FAM155A,REEP1" Drug 5431_DN Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SEMA6A,ALCAM,ARRB1,MARK4,SYNJ2,GYG2,MAGI1,CLGN,TAOK2,QKI,C2CD2L,RHOBTB1,OPTN,NCALD,FGF12,FGFR1,FHL1,SEMA4D,MPP6,INPP5K,RAB30,GRIK5,HNMT,INPP5B,KIF2A,IPO5,LIG4,LRP12,ELOVL2,GTDC1,ZKSCAN3,ZBTB43,CLASP2,VPS13A,ANKRD12,EXOC7,SLC44A1,SEMA3B" Drug 1701_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBB2,ARRB2,MPDZ,CFLAR,SYNJ2,CCNT1,ABCG1,DZIP3,GIT2,EZH1,ZNF589,FER,FAM49B,TJAP1,IL6ST,KCNH2,MAPT,MIA2,MMP16,PIK3R1,SNX10,STRN3,POLG,RPS6KA2,KIF16B,EPN2,BTBD7,ERC1,TROVE2,CAMTA2,PHLDB1,TACC1,KIAA0930,CRTC1,PARD3,HIRA,UBTF,TFIP11" Drug 2304_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADORA1,ADORA2A,ADRA1D,ATP2A2,GYG2,SGCE,CD86,CBFA2T2,CRLF1,TAOK2,AKAP7,NRG2,GREB1,SEC14L5,SNPH,SPOCK2,NRN1,OLFM1,FGFR1,GNAO1,STON1,MAP2,ADAM22,MYT1,PDE1C,PTPRN2,ZSCAN2,C1orf54,CNKSR2,PKNOX2,CXXC4,SNCA,KDM4B,HECW1,SPART,GPR161,TNS1,CLIP2" Drug 2895_DN Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,APC,MARK4,RASL11B,HAP1,CAMK2G,SEPT7,AKAP7,CRY2,MAML1,DAPK3,MFAP3L,LYPD1,PARD6A,EIF4G2,PRELID3A,GPD2,TJAP1,KHK,ADAM22,NPR2,NPTX1,NTRK2,PLCD1,LRP12,PRKAR1B,RELN,CNNM2,ABLIM3,PREX2,CXXC4,ZC3H13,ARHGAP26,PCDHA5,TK2,CDK20,ZFP37,GDPD5" Drug 5083_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "CDC42BPA,PPFIA3,SLITRK5,DZIP3,DCAF4,ARHGAP32,ARHGAP24,RUSC2,DPH1,EDIL3,ETV1,RRAGB,B4GALNT1,COPS8,CNTRL,MUM1,BACH2,FAM69A,PDE4D,PLCD1,SNRK,WDR25,SUGCT,ZFP30,SMARCD3,TMCC1,PDZD2,SPTAN1,CEP68,CRTC1,GPR161,TK2,TNS1,TPM2,UBE2H,UBTF,SPHK2,MAP3K12" Drug 1831_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABR,ABHD6,ADGRF5,APOC1,CDK10,ADAM15,CFLAR,CA12,SCARB1,AP4M1,HOMER3,DZIP3,SGSM2,FEM1B,ERCC2,FHL1,GAD1,DISC1,INPP5K,USP19,GPER1,AGFG1,SMAD1,MX1,NFYA,PLEC,GRAMD1C,TMEM260,KIRREL1,SIRT2,BTBD7,ZNF415,SS18,ARHGEF9,EXOC7,LMF1,NT5M,SMIM8" Drug 6129_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AMPH,CDC42BPA,APOC1,ADGRB1,BMP7,SYNJ2,CFAP410,RUNX1T1,ENTPD2,CHRNA4,TAOK2,CABP1,RASGRP2,KAT8,PDLIM5,TDRKH,TJAP1,KCNN1,LAMA2,MGAT3,MMP16,NRCAM,PDE4A,PDE4D,PLCD1,MORC4,CNKSR2,PKNOX2,TMCC1,RBM34,DOP1A,ARHGAP26,ASTN2,DNAH7,VSNL1,REEP1,SH3GLB2,PARP11" Drug 2276_DN Flumequine [42835-25-6]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,C1QTNF3,AMPD3,PPP4R4,ARRB1,PLA2G4C,MARK4,SYNJ1,CAMK2B,RUNX1T1,SLIT2,QKI,EDNRA,PLXNC1,ZNF589,FER,AGAP2,TPK1,SRCAP,AHDC1,MSL3,GNG4,KCNH2,MMP16,ADAM22,PLCD1,POLG,MAPK10,ZDHHC14,GSTCD,TCP11L1,CXXC4,TROVE2,CLSTN2,AP4E1,SLC30A3,DNALI1,KCNAB1" Drug 2220_UP Nicergoline; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,NME5,ALCAM,ATP1A3,ATP2A2,ATP2B2,ALDH7A1,SYNJ1,ST3GAL5,CAMK2B,ASIC3,CHRNA4,COL9A3,JAKMIP2,HSD17B14,RASGRP2,SPEG,PTK2B,FYN,TRAF3IP2,GPD1,ICA1,IL6ST,ITGA7,NF1,NTRK2,PFKFB2,MAPK7,SAMD9,SEMA6D,SH3BP2,FRMPD1,ASAP3,IZUMO4,PEG10,CLIP2,KAT6A,DPF3" Drug 387_DN "estradiol, USP; Down 200; 0.01uM; HL60; HG-U133A" Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ACTN1,BEGAIN,APOC1,AQP6,ADAM15,BMP7,CDH2,CACNA2D2,SLIT2,CLCN3,RAB26,RGS6,TBC1D5,C2CD2L,ING4,KAT8,ANKFY1,HPGDS,HTATSF1,LYRM9,MYO9A,NEFH,POLG,MASP1,VPS13C,SUSD4,RGS12,STUM,ASAP3,ZC3H13,SST,ST5,CEP68,PHLDB1,SZT2,NR2C2,TRIO,KLC2" Drug 3356_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,ADRA1D,BIN1,KCNAB2,PDE8B,CNTN1,DCAF4,DNM1,RCAN1,ING4,IQCG,PDLIM5,FAM49B,GCNT2,MSL3,GRB10,CACFD1,KCNN2,KHK,LIG4,SMAD1,MAP4,PRKAR1B,MAPK7,WDR25,CCDC25,TCP11L1,RPS6KA2,PREX2,FAM214B,ZHX3,ST5,PLCB1,RPGRIP1L,VIPR2,XRCC4,ZNF45,SMIM8" Drug 6894_DN SB 203580; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,ABR,OGT,SCARB1,LARGE1,CHN2,WHRN,PDE4DIP,RCAN1,EDNRA,FAM13A,APH1A,ING4,MRNIP,HSD17B14,ANKMY1,SCARA3,GPER1,MAN1B1,TM6SF1,NFIX,RETREG1,PLEC,MAPK7,GRAMD1C,APTX,WDR25,RGS3,ASAP3,UNC5B,LHPP,TMPO,R3HDM1,HIRA,LMF1,WNT7A,EMSY,DPF3" Drug 3814_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "LTBP4,FGD2,ATP2B2,TAOK2,STOML1,HAPLN1,DGKG,DTNB,CALCRL,PIPOX,FGFR3,FLT1,EFCAB2,SIGLEC8,DISC1,ALDH1L1,RAB30,LILRB4,ATXN2L,ICA1,KCNF1,MARK1,KITLG,AFDN,MYT1,NELL2,NPTX2,GPR85,PNMA3,RET,RGS12,RORB,EMID1,PKNOX2,SPTB,THRA,SPHK2,HRASLS" Drug 436_DN HA-1077 dihydrochloride; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "MTUS1,GAS7,ZSCAN18,HIP1R,SEPT7,NCOR2,C2CD2L,FAM13A,F5,FKTN,BAIAP2,HPCAL4,SEPT9,GLYR1,ZNF638,GRIK5,SOX21,ICA1,KCNJ5,KTN1,LAMP2,MAPT,MMP17,NACA,NF1,NTRK3,NLE1,NUDT11,ATXN2,CHD9,FAIM2,DOK5,DBNDD2,PLCB1,IQCE,DMXL2,METTL3,UCHL1" Drug 2816_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "KCNAB2,CDK13,DNAH17,N4BP2L1,CAMK2B,ARHGEF1,RCBTB2,ASIC3,SULT4A1,AKAP7,RCHY1,RIMS2,DMPK,SHANK1,EDIL3,C3orf18,HSD17B14,KHDRBS3,DLL3,OGA,ERAP1,GRB10,GSN,IRAK3,ICA1,INPP5B,KCNN1,MAP4,GIT1,MINDY2,PTPRD,C1orf54,RGS4,KCTD17,PKNOX2,IQSEC2,WSCD1,PARP11" Drug 3223_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,GAS7,PRX,CDK13,CFLAR,SYNJ1,CBFA2T2,CDH2,CPS1,NCOR2,CNTNAP2,ARHGEF4,SPOCK2,MFAP3L,FAM198B,ZNF589,FGF12,FHL1,PRELID3A,LYVE1,RUNDC3A,ATXN2L,ICA1,KCNJ5,MATN3,ADAM22,OPRL1,GPR85,PLXNB1,PPP5C,ZSCAN2,TCP11L1,SLC14A1,R3HDM1,TRPM2,FAM155A,FLRT2,KCNK12" Drug 3797_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AGT,LTBP4,APAF1,ATP2B2,ATP6V0A1,NRP2,SCARB1,TPP1,CNR1,CABP1,CSF1,CSF1R,IPCEF1,SPOCK2,EDNRA,RASGRP2,PIPOX,ABCA8,ALDH1L1,GLYR1,PADI2,ICA1,IRF8,PNMA3,POU6F1,ZSCAN32,ZMAT4,RET,RGS12,KLHL11,PKNOX2,BTBD7,HECW1,TNS1,TPM1,FLRT2,SPHK2,KCNAB1" Drug 3092_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADD2,ADORA1,AMPH,CASK,ARSE,PDE8B,ADAM23,CACNA1I,HIP1R,CNTN1,CREM,SH2B1,ABCG1,FHL1,GAD1,HPGDS,POLL,GNG4,GSTM5,ELOVL5,HNMT,MAP4,MYO6,PCDH9,PDE1C,TMEM104,RGS12,ST6GAL1,PKNOX2,PDZRN3,DOK5,DDN,SSTR2,RPGRIP1L,ZFPM2,TK2,TNS1,NT5M" Drug 1380_UP Spironolactone [52-01-7]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,APAF1,CDK10,ARNTL,RIPK1,SLC25A14,CBFA2T2,SRSF11,HINFP,CTH,ZNF804A,VPS26C,CD320,FCGRT,ATP2C1,GLYR1,GRIK5,MAN1B1,IDH3A,SLC25A23,MINDY2,PTX3,ZDHHC4,SGK1,KBTBD4,ELMO2,GLT8D1,UHRF1BP1L,KDM4C,TSPYL2,SEPT8,TBL1X,CHST8,CBX5,CA14,ZKSCAN5,EVI5,URM1" Drug 7204_DN Noscapine [128-62-1]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBB2,NCOA1,KIF1A,SYNJ1,PTBP2,SCARB1,SRSF11,STOML1,CREM,LRIG1,DZIP3,ARHGAP32,KIAA0586,DBN1,MED12,DTNA,FEM1B,CELSR3,SUGP2,IRAK4,COQ7,SEMA4D,TXNL4A,GRB10,BTN2A1,MUM1,KHK,RETREG1,MBOAT7,RXRA,MAPK12,SBF1,ZKSCAN3,SMARCC2,KDM4B,CLASP2,ELOVL4,GAN" Drug 6702_UP Niacin [59-67-6]; Up 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "OGT,APAF1,APC,DDO,ARHGDIG,CDK13,NRP2,LDLRAD4,CFAP410,KALRN,RUNX1T1,CBFA2T2,ARHGAP33,CHRNA4,PCYT1B,NCOR2,CSF1,MFAP3L,ING4,RASGRP2,ST3GAL6,FYN,ITGA7,AFDN,ADAM22,P2RX7,P2RY1,PALM,PIK3R1,PTPRN2,SUGCT,FRMPD1,SLC9A5,IZUMO4,PCDHGB6,HIRA,EVI5,FAM13C" Drug 3341_UP Reserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,GAS7,APOC1,DNAH17,ZSCAN18,CACNA2D1,CALB2,CHN2,TPP1,NRG2,NECTIN3,NCOR2,CSF1R,RIMS2,HIPK3,C3orf18,ERBB4,FAM198B,FHL1,GAD1,DISC1,TDRKH,PCLO,GRIK5,PRDM5,NF1,NNAT,STRN3,KHDRBS2,TRIM68,RPS6KA2,SATB1,SNCA,JMJD6,WSCD1,OBSL1,LAT2,PLSCR4" Drug 6362_DN Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BRAP,APLP1,ATP2A2,ADAM23,CFLAR,LDLRAD4,QKI,VCAN,RUSC2,EDNRA,SUGP2,MRNIP,HSD17B14,BAIAP2,TRAF3IP2,INPP5K,GPER1,GRIK5,GUCY1A1,HSF2,MX1,SLC11A2,PLCD1,MAPK3,ZNF671,ASAP3,AMBRA1,SMARCA4,TMCC1,ASTN2,SMG6,WSCD1,PLPPR2,TRIM9,NDRG4,SH3GLB2,DPF3,RNF146" Drug 5798_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,ADGRF5,GAS7,KIF1A,CAMK2B,FOXN3,NRXN3,CNR1,IQCK,WHRN,CHRDL1,DTNA,EDIL3,EGFR,ERBB4,ZNF391,REEP2,CORO2B,DCTN2,PRELID3A,GRIK5,IL12A,AFF1,ADAM22,PCDH9,PDE4D,PRKCB,ZSCAN32,PTPRN2,RGS12,RASA3,CXXC4,ZHX3,MCF2L,TBCEL,TRIO,SPHK2,KCNAB1" Drug 4733_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PPFIA3,CFLAR,MTMR2,CA12,ARHGEF2,FOXN3,FAM189A2,ARMC8,LRIG1,PDE4DIP,DBT,MFAP3L,NR1D2,RRAGB,ACSL4,FGFR1,PDLIM5,GLYR1,GPD2,MAP4K5,IL6ST,INPP5B,MIA2,KITLG,NF1,NFYA,RETREG1,STRN3,POLG,ZNF821,FNDC3A,FAM214B,LIMCH1,THSD1,NXT2,IQCE,TPM1,CDK20" Drug 3396_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,ADORA2A,KIAA1324,SEMA6A,APC,ALDH7A1,N4BP2L1,HIP1R,CBFA2T2,AKAP6,VCAN,SEC14L5,RASSF2,DAPK3,CAMKK2,FYB1,MSL3,GPER1,GPR37,INPP5B,KIF5A,L1CAM,LMO2,CNOT4,NPR2,FXYD1,CEP41,KLHDC8A,SLC11A1,CXXC4,TSNAXIP1,ZC3H13,PLCB1,ZEB1,TRPM2,UGT8,PHTF2,SENP7" Drug 2554_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PKP4,APBB2,PPP4R4,BMP7,CACNA1G,CFAP410,AP4M1,ARHGAP33,CLGN,HOMER3,NRG2,SLITRK5,RIMS2,SV2B,E2F5,HIPK3,FAM13A,ZNF549,CDKL3,PDLIM5,CAMKK2,GPD2,GSN,MAPT,ZNF862,PURG,STRN3,CPEB3,PREX2,ARHGAP26,SPART,ATP10B,ARHGEF9,SYT1,HIF3A,PIK3R5,TRIO,JPH3" Drug 7390_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "CDC42BPA,KCNAB2,APBB2,ATP1A3,SLC4A4,PDE4DIP,RUSC2,CHRDL1,DPH1,EIF4G2,MTSS1L,ETV1,RRAGB,TAOK3,FGF1,OLFM1,FGFR1,OGA,DENND2A,LPAR4,FAM69A,NTRK3,CLDN11,PPARA,FAM184A,FBXW7,RXRA,TRAPPC13,ASAP3,DOCK9,TMEM121,AMACR,ZKSCAN5,VIPR2,XRCC4,REEP1,EVI5,UBE3B" Drug 3885_DN Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,BIN1,APC,FAM131A,PPFIA3,MARCH3,SLC2A11,KIF1A,SYNJ2,MAGI1,DNM1,DMPK,EDNRA,ING4,FAM198B,MUM1,IL6R,MMP17,GIT1,NPTX1,RETREG1,CEP97,ZCWPW1,ASAP3,LIMCH1,ZNF423,ARHGAP26,IQSEC2,TTBK2,VPS13A,KIAA1107,SMG6,HEY1,TK2,CABIN1,KCNK12,ZBTB14,NDRG4" Drug 5681_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBB2,APOC1,ARRB1,ARRB2,ATP6V0A1,TAOK2,ENTPD4,SIPA1L1,PDE4DIP,GPRASP1,DAPK3,DTNA,MRNIP,ZNF589,FGFR1,ANKFY1,EFCAB2,TRAF3IP2,COPS8,GLYR1,MSL3,CNTRL,RNFT2,HNMT,INPP5B,MBNL1,ADAM22,SMIM7,FSD1,NEK11,RPS6KA2,LIMCH1,USP33,NXT2,ELOVL4,MAP3K12,EVI5,PHTF2" Drug 3107_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ALK,BIN1,BMP7,MYRF,CAMK2B,CLDN10,CACNA2D2,ASIC3,CHN2,VAX2,SULT4A1,CLOCK,SPOCK3,SGSM2,CDON,ZNF549,F5,HPCAL4,SRCAP,RUNDC3A,GNAL,GPD2,ITPKA,SCAMP5,LYRM9,NF1,PPP5C,PRPH,MAP6D1,SEMA6D,SBF1,GALNT10,ST6GAL1,CNKSR2,TMCC1,PLCB1,CDK20,PLPPR2" Drug 4729_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "FAM131A,SLC2A11,CFLAR,ARHGEF1,ARHGEF2,FOXN3,HOMER3,NCOR2,DBN1,PARD6A,MBNL2,ING4,STX2,NCALD,AFF2,GAD1,SEPT9,TDRKH,MAP4K5,ATXN2L,AGFG1,IL6ST,KCNF1,MAP4,NF1,RETREG1,STRN3,PRKAR1B,ZNF423,TROVE2,PLCB1,TBL1X,DICER1,TMPO,HIRA,ZNF45,SPHK2,MAP3K12" Drug 502_DN sodium 4-phenylbutyrate; Down 200; 200uM; SKMEL5; HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,NDRG2,PKP4,PPFIA3,ATP1A3,BMP7,CD86,B4GALT6,COL4A5,CDC42BPB,ARHGEF10,DGKG,DRP2,ZNF589,FGFR1,FGFR3,TRMO,LYVE1,HPGDS,CACFD1,FAM107A,GUCY1A1,MAN1B1,HNMT,KIFC3,FXYD7,NF1,PRKAR1B,RGS3,SMARCC2,ZSWIM8,IQCE,SIRT1,TPM1,SSBP2,UGT8,KLC2,SLC17A7" Drug 3305_UP Cisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,KIAA1324,SPARCL1,CDC42BPA,APBA2,CACNA1A,RHBDL1,RCBTB2,FOXN3,QKI,HOMER3,CSF1R,CYBB,DAPK3,JAKMIP2,MTSS1L,SEPT9,GRIK5,GRM8,SOX21,ATXN2L,LSS,MBP,PLCD1,PLTP,SLC9A5,TSNAXIP1,ZNF423,ARC,KIAA1107,WSCD1,SZT2,DOCK9,RUNDC3B,KCNK12,SPHK2,KCNAB1,KAT6A" Drug 6031_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,AP2A2,C1QTNF3,APBB2,CDC14B,CDK10,USP2,CBFA2T2,CRLF1,SLIT2,VCAN,GREB1,RASSF2,TMCC2,KAT8,FGF12,FGFR1,DISC1,SRCAP,GLYR1,POLL,GRIK5,INPP5B,SMAD1,ADAM22,RETREG1,PLXNB1,PPP5C,RPS6KA2,SEMA6D,ASAP3,SLC6A8,PHLDB1,TACC1,CRTC1,CHST8,TK2,ZNF45" Drug 3009_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "CDC42BPA,APC,ARHGDIG,BAIAP3,HIP1R,SLC16A4,SLC4A8,CRYBB1,NCOR2,DZIP3,RIMS2,RIPOR2,EDN3,HIPK3,SRPK3,RASGRP2,CHST15,FHL1,SEPT9,GPD1,GSN,GUCY1B1,ATXN2L,SCIN,ADAM22,SETD4,PDE4A,RGS4,RGS12,KLHL11,SLC11A1,AP4E1,TK2,TPM2,TRPS1,SSBP2,KCNK12,SPHK2" Drug 4611_UP Tyloxapol [25301-02-4]; Up 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BEGAIN,CACNA1G,CACNA2D1,DLGAP1,CSF1,MFAP3L,EDN3,ZNF589,DOT1L,FYB1,GNAL,GNG4,LILRA2,ICA1,KCNJ5,LAMA2,NF1,NTRK3,PDE4A,RETREG1,PPP2R2B,SNRK,NEK11,SCN2B,SLC9A5,SNCA,SOX3,SPTB,DDN,SAMSN1,ARC,PCDHGA10,OBSL1,ICAM5,TUBB1,VGF,KCNK12,GAN" Drug 7401_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADRA1D,ADAM15,BACH1,ADGRB2,KALRN,P2RX6,VCAN,CNTNAP2,ARHGEF4,EXOG,DRP2,IRAK4,ING4,FGF13,OGA,FYB1,ERAP1,INPP5K,GLYR1,GRIK5,LMO2,PDE4D,PRKAR1B,SAMD9,ZCWPW1,NEK11,MAPK12,ZFP30,AMBRA1,ST6GAL1,KANSL3,SPTAN1,TMEM121,TRO,HIRA,VIPR2,SLC17A7,KCNAB1" Drug 4020_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ACHE,AMT,PPFIA4,DDO,PTCH2,ADAM23,BAIAP3,CCK,AKAP5,CSF1,RIMS2,INTS1,DRP2,EPB41,FGFR1,AGAP2,SEMA4D,EFCAB2,FYB1,SIGLEC8,GATM,LYVE1,RUNDC3A,CACFD1,KCNJ5,ADAM22,NTRK3,PALM,ENPP2,LRRN3,KANSL3,CXXC4,SOX15,SPTAN1,ADGRL3,THRA,NT5M,NLRP3" Drug 1485_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "KCNAB2,APBB2,APC,BCAS1,CFLAR,SYNJ2,SCAPER,TAOK2,SIPA1L1,GREB1,DAPK3,DBT,MFAP3L,DMPK,EDNRA,MBNL2,RRAGB,ALDH1L1,GLYR1,ADAMTS13,INPP5B,KCNH2,KCNJ5,MATK,NPTX1,PLCD1,ZNF493,ANKRD6,CXXC4,USP33,ELOVL4,EXOC7,IQCE,CHST8,AP4E1,CDK20,FLRT2,KCNAB1" Drug 6590_UP prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BIN1,GAS7,MADD,MTMR3,GYG2,CACNA1I,MYRF,CFAP410,MFAP3L,DTNA,EGFR,SCML2,BAIAP2,CSPG5,CNTRL,GRB10,MAP4K5,NXPH3,MAN2A2,ADAM22,MYO7A,ZNF862,CNOT4,SNRK,ZFHX4,NEK11,RPS6KA2,FERMT1,EPN2,SLC9A5,RCOR3,ATP10B,PCDHA6,CHST8,HEY1,TPM1,RPRM,LAT2" Drug 3112_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BIN1,APOC1,MARK4,ADAM15,MTMR3,B4GALT6,KIAA0753,TNK2,NCALD,KAT8,GAA,INPP5K,MSL3,ATXN2L,LAMA2,MAP4,AFDN,N6AMT1,NINJ2,OGG1,P2RY1,PFKFB4,PLCD1,PLCL1,TMEM104,SBF1,PPM1E,AMBRA1,KDM4B,KDM4C,SPTAN1,IQSEC2,ZC4H2,JMJD6,FLRT2,LMF1,ATP6V0E2,NT5M" Drug 4218_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ACHE,PPFIA4,PPP4R4,AZGP1,RGS11,KSR1,BMPR1B,CA4,CCK,USP2,SLC16A4,LARGE1,DLGAP1,NRXN3,FAM149A,COL9A3,GAL3ST1,CRYBB1,MRNIP,EPB41,RASGRP2,RUNDC3A,TOX3,KCNJ5,MMP16,LRRN3,PTH1R,PTPRG,RASGRF1,SCN2B,RASA3,KANSL3,DOP1A,TACR1,TLR4,NPL,FLRT2,XRCC4" Drug 3603_DN Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ARRB1,BMP7,SCAPER,ARHGAP33,SLIT2,RAB28,QKI,NCOR1,ZNF337,DAPK3,HIPK3,COQ7,STX2,ZNF589,SYT17,ALDH1L1,ZNF276,MSL3,TDRKH,CNTRL,GSN,MUM1,IL6ST,MAP4,CNOT4,PPP5C,GSTCD,TCP11L1,KDM4C,THSD1,ASTN2,PCDHA6,AP4E1,HEY1,TK2,PLPPR2,GDPD5,LAS1L" Drug 2111_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AK2,KCNAB2,APOC1,CDK13,PDE8B,BCHE,SYNJ2,HAP1,SCARB1,ARHGAP33,ARHGAP22,HOMER3,SNPH,DBT,HIPK3,CELSR3,MBNL2,ETV1,B4GALNT1,SYT17,GPR37,KCNN1,GIT1,CNOT4,NTRK2,CNTLN,TRAPPC13,SCN8A,FNDC3A,PEX26,ZKSCAN3,DDN,TROVE2,ASTN2,SMG6,TCF4,SYNE1,NT5M" Drug 2486_DN Trimethadione [127-48-0]; Down 200; 28uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,NDRG2,MTUS1,SYNJ2,IQCK,HINFP,ABCG1,AATK,CSNK1E,USP6NL,TM9SF4,DTNA,MBNL2,TUBD1,DLC1,SRCAP,USP19,ICA1,TJAP1,JAK2,MYO7A,SLC11A2,PLCD1,RIPOR1,GSTCD,SEC14L1,MRAS,PEX26,EPN2,FAM214B,ZKSCAN3,TSPYL2,TROVE2,SEPT8,PDLIM2,TCF4,ICAM5,TRPS1" Drug 4962_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AMT,APC,PPFIA3,CDC14B,CFLAR,SCARB1,B4GALT6,PLAA,QKI,HINFP,GIT2,DTNA,TOM1,CDKL3,GALC,INPP5K,SRCAP,CACFD1,ITPKB,IPO5,MAP4,MAPT,KITLG,NF1,KCTD15,PLCD1,PLEC,SLC25A23,LRP12,TMEM104,RAD51D,ELMO2,BTBD7,LIMCH1,CEP68,VPS13A,PLPPR2,TFIP11" Drug 6297_DN Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BRAP,PPFIA3,ZBTB10,CFLAR,SOCS6,VCAN,FAM169A,SLITRK5,PPP6R2,ZNF337,DYNC1I1,RCAN1,OPTN,SUGP2,STX2,DENND4A,RACK1,PRRC2B,HNMT,MAP4,MEIS1,NEK1,PIK3R1,PLCD1,FA2H,WBP1L,SH3TC2,GAL3ST4,FAM102A,KDM4D,SMARCA4,KDM4C,ZBTB43,JMJD6,ZMAT3,XRCC4,MAP3K12,PCBP4" Drug 6360_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PPP4R4,MARCH3,CFLAR,ST3GAL5,CACNA1I,NRXN3,CREM,ABCG1,SUSD5,RIPOR2,CDON,DTNA,EDIL3,VPS26C,FYB1,DISC1,ALDH1L1,GLYR1,KHK,MX1,PDE4A,PLCD1,C19orf57,GRAMD1C,WDR25,PTPRH,RPS6KA2,CNKSR2,DZIP1,SLC2A5,ZNF334,IFT122,LIMCH1,ADGRL3,THRA,PIK3R5,XRCC4,JPH3" Drug 2653_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,C1QTNF3,BIN1,BMP7,SYNJ2,BAIAP3,CFAP410,HAP1,PLEKHB1,LHX2,ARHGEF6,GREB1,LYPD1,DNM1,PLXNC1,ING4,CSPG5,POLL,GSN,HNMT,LIG4,MBD1,NNAT,SLC25A23,RAD51D,ZDHHC14,RGS3,CCDC25,EMID1,RASA3,SH3BP2,SNCA,SYN2,EXOC7,WSCD1,NSD1,TMEM121,MPPE1" Drug 1157_DN LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADORA2A,APC,MARK4,CAPN3,CBFA2T2,SOCS6,TPP1,SH2B1,CSF1R,ZFYVE16,FRY,ERCC2,FECH,TRAF3IP2,LILRA2,CACFD1,ELOVL5,JAK2,MATK,NEFH,NF1,SETD4,GPR85,PLEC,TMEM104,ZSCAN32,GSTCD,CCDC25,SEC14L1,SMARCA4,SPATA7,ERC1,TSPYL2,PBLD,EXOC7,WBP2,UBTF,HPS4" Drug 2479_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADD2,SRPX,AMH,AMPH,CDC42BPA,CDK10,DNAH17,BMP7,CHN2,CHRNA4,SULT4A1,CREM,ABCG1,RIMS2,EDNRA,RRAGB,STON1,ADAMTS6,RASSF8,ITPKA,MAPT,NPR2,CLDN11,PFKFB4,PPP2R2B,GDPD2,PTPRO,KLHDC8A,NEK11,TCP11L1,ARHGAP26,ATP10B,CHST5,UGT8,VGF,VSNL1,PRDM10,SLC17A7" Drug 5638_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "TRMT9B,CDK10,PDE8B,MARK4,ATP2A2,SYNJ1,CACNA1I,CBFA2T2,TAOK2,STOML1,SULT4A1,SLC4A8,ARHGEF10,PDE4DIP,CDON,VPS13B,IGSF6,FHL1,GAD1,INPP5K,GNG4,RNFT2,INPP5B,MSI1,ZNF862,PDE4A,FAM184A,CARF,ABLIM3,DOK5,ZHX3,TBCEL,PCDHA5,TMEM121,ZNF34,PLPPR2,ZNF711,SLC17A7" Drug 5944_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AP2A2,CDC14B,ARNTL,NUMB,RASL11B,ALDH7A1,CACNA1I,CAMK2B,USP2,CLGN,SULT4A1,CABP1,TMCC2,CDON,RCAN1,C3orf18,RRAGB,DLC1,FGFR1,PDLIM5,GNAL,HLF,IRF8,INPP5B,KCNH2,PACRG,PLEC,MAPK7,PTPRH,PTPRO,SALL1,PHLDB1,PLCB1,ADGRL3,TRIM2,TRPM2,KAT6A,TIGD6" Drug 3931_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BBOX1,BIN1,MARK4,AZGP1,PICK1,WHRN,MYRIP,SNCAIP,RIMS2,SV2B,SPOCK3,DYNC1I1,ECM2,HIPK3,RASGRP2,SPEG,REEP2,ZNF589,CSPG5,NSG1,POLL,PCLO,GRIK4,GRM2,IGF1,PCBP3,PFKFB2,PRKCB,GDPD2,ELOVL2,SATB1,STUM,CDK19,TBCEL,TRO,UGT8,OSBP2,SLC30A3" Drug 665_UP "estradiol, USP; Up 200; 0.01uM; PC3; HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBB2,SEMA4G,EIF4G3,STX16,NRP2,BMP7,CNOT8,FAM189A2,TMEM184B,ARHGEF6,NCOR2,INTS1,SPATA2,DRP2,MBNL2,ZNF589,RUNDC3A,CACFD1,SLC2A6,MAN1B1,HMGCR,KCNN1,MAN2A2,MYO6,CLDN11,PTH1R,ZSCAN32,RGS3,RNASE1,SGK1,RCOR3,TSNAXIP1,SPART,PHF24,ZNF142,EVI5,SLC17A7,PDSS2" Drug 4690_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,AP2A2,TRMT9B,GAS7,PPP4R4,ALDH7A1,CFLAR,CAMK2G,QKI,HOMER3,GREB1,IRAK4,SPEG,RRAGB,DLC1,FGF13,OGA,GAD1,GALC,GSN,ICA1,MID1,ADAM22,NF1,CNOT4,MAPK10,RGS12,ZNF821,FBXO11,SYBU,DOK5,TROVE2,PHLDB1,WSCD1,CLIP2,LAT2,PARP11,ADAMTSL3" Drug 1824_DN Atracurium besylate [64228-81-5]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "MADD,ADAM15,CFLAR,CA12,SCARB1,AP4M1,CSF1,VCAN,TBC1D5,DAPK3,SGSM2,EDN1,VPS26C,FHL1,NOP56,PDLIM5,INPP5K,SRCAP,AGFG1,NFYA,NPR2,OGG1,PDPK1,KCTD15,PLEC,POLG,ELOVL2,DCUN1D2,SAFB,SIRT2,ELMO2,IFT122,SS18,SYT1,FAM155A,PLPPR2,UPF3A,URM1" Drug 7443_DN Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PKP4,PPFIA3,MPDZ,SYNJ2,TAOK2,STOML1,CSNK1E,SIPA1L1,PDE4DIP,GPRASP1,ZNF337,TBC1D5,EDNRA,TNK2,KAT8,FGFR1,EFCAB2,CGREF1,B4GALNT1,CNTRL,MAP4,MPP2,PPP2R2B,ZCWPW1,ABLIM3,ZKSCAN3,KDM4B,FNBP1,ELOVL4,STXBP1,ASTN2,KAT6B,TPM1,UBTF,PLPPR2,VIPR2,ZNF23,ST7" Drug 4573_DN Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "C1QTNF1,PKP4,CDK10,CFLAR,PLEKHB1,TPP1,ARMC8,CPS1,AATK,PDE4DIP,SNPH,EXOG,EDNRA,ETV1,ST3GAL6,OGA,GAD1,MAP4K5,MITF,MT1M,ZNF862,CNOT4,PFKFB2,GRAMD1C,CNNM2,PID1,RXRA,ZNF821,ZNF415,ELOVL4,SYT1,KIAA1107,WSCD1,FAM155A,VIPR2,PCBP4,FZD3,SMIM8" Drug 4246_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,SEMA7A,KCNAB2,PPP4R4,ZSCAN18,SYNJ1,CBS,ARHGAP22,SUSD5,SEC14L5,PYGO1,RIPOR2,MFAP3L,EXOG,DTNB,FGF1,DCTN2,PDLIM5,PCDH17,GNAO1,ADAMTS13,NF1,NPR2,NPTX1,PTPRN2,C1orf54,GAL3ST4,RGS4,KCNIP1,SALL1,SH3BP2,SLC2A5,OGDHL,IZUMO4,KCNK12,XRCC4,ZNF225,NT5M" Drug 5486_DN Tridihexethyl chloride; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "C1QTNF3,PPFIA3,DNAH17,KIF1A,BCL7A,SCAPER,C5,MAGI1,COL4A5,AKAP12,DCAF8,KIAA0586,GIT2,RCAN1,EDNRA,COQ7,SCML2,DLC1,FHL1,FAM49B,FYN,ITPKB,MAPT,MITF,LYRM9,OXTR,PDE4A,LRP12,SUSD4,SGK1,SH3BP2,FAM214B,ELMO2,TACC1,FBXW11,CABIN1,PLPPR2,TIGD6" Drug 4096_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BEGAIN,PPFIA4,DDO,CACNA2D1,DGKI,NRXN3,STOML1,CSF1,CSF1R,IPCEF1,PPP1R16B,C2CD2L,SPOCK3,ING4,SRPK3,DCTN2,PRELID3A,SIGLEC8,GFER,PCDH17,GNAL,GNG4,KCNB1,KCNQ3,TM6SF1,AFDN,NF1,ENPP2,PLCD1,PPP2R2B,PTPRB,RFX2,RPS6KA2,ZNF334,SNCA,TRO,UCHL1,HRASLS" Drug 5678_DN Thonzonium bromide [553-08-2]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RIPK1,CA4,TBRG4,HOMER3,ARHGEF10,SIPA1L1,DZIP3,MFAP3L,EIF5,ZNF589,PDLIM5,PRELID3A,CGREF1,TRAF3IP2,INPP5K,MALT1,GLYR1,RASSF8,HNMT,MAPT,MMP16,ADAM22,NF1,NFYA,SLC11A2,PDE4A,TMEM104,PTPRE,FAM184A,SLC22A4,ELOVL4,AP4E1,CABIN1,ZNF24,ZNF74,SMIM8,PHTF2,ACTR3B" Drug 3695_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APAF1,BCAS1,ATP2B2,ADAM23,KSR1,BMP7,LDB2,CBARP,NRXN3,RCHY1,EGFR,EPHB1,F5,HPCAL4,ZNF44,ALDH1L1,RUNDC3A,GRM2,LSS,FXYD1,PTPRB,ZSCAN2,SUSD4,GAL3ST4,RFX2,RGS4,CARF,CPEB3,SOX3,IZUMO4,SMG6,PCDHGA10,TK2,TNS1,FLRT2,SPHK2,SLC17A7,EPM2A" Drug 7048_DN GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SYNJ2,CACNA2D2,SOCS6,PLEKHB1,SH2B1,FAM131B,TBC1D5,GIT2,EDIL3,FHL1,ANKFY1,DENND2A,SYT17,ARFIP1,GLYR1,MBNL1,MN1,PDE1C,PLEC,TMEM231,CEP97,FBXW7,CSRNP3,FAM102A,ST6GAL1,ELMO2,TMCC1,PEG10,SPTAN1,TROVE2,CEP68,FBXW11,TRIM2,SZT2,DNAH7,TRIO,UPF3A,AAAS" Drug 435_UP "novobiocin sodium, USP; Up 200; 100uM; PC3; HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,ADORA2A,APBA2,APC,GAS7,ARNTL,ATP6V0A1,BMP7,CACNA1I,ARHGAP33,DLGAP2,CHN2,DTNB,EIF4G2,ELN,COQ7,FER,FGFR3,DISC1,SRCAP,AHDC1,GFRA2,MBP,AFF1,ACSS3,ATXN7,ASAP3,SLC8A1,SNAP25,SPART,SSTR2,TBL1X,DMXL2,GPR161,TRO,TUBB1,MPPE1,AAAS" Drug 1828_UP Naproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BIN1,SHROOM2,ADGRB2,MPDZ,CFLAR,SYNJ1,FOXN3,NRXN3,ELMO1,EDNRA,FGF1,CSPG5,ERAP1,GNAL,GNG4,GRIK5,CACFD1,BACH2,IL6ST,SCAMP5,CNOT4,SLC11A2,CNNM2,NUDT11,STUM,SH3GL3,PEX26,CCDC88A,FNBP1,SPTB,CAMTA2,SYN2,ZNF34,BEX4,CABIN1,ZNF74,SPHK2,AAAS" Drug 3033_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PKP4,APAF1,KIF1A,AZGP1,LDLRAD4,CAPN3,KYAT1,QKI,CPS1,DBT,RUSC2,EXOG,HIPK3,COQ7,FCGRT,ZNF589,CAMKK2,KHDRBS3,INPP5K,LILRA2,SPACA9,ITGAM,NFYA,CNOT4,ENPP2,ZNF671,PPM1E,KDM4C,SS18,FBXW11,TBL1X,TCF4,DMXL2,FLRT2,LMF1,LAT2,ZNF189,PHTF2" Drug 2336_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SYT13,AMPD3,ARNTL,NUMB,BMP7,SCAPER,CAMK2B,SLC25A14,SLITRK5,COQ7,NCALD,CDKL3,ST3GAL6,PRKAG2,SMC2,PDLIM5,CELF1,ALDH1L1,IL6R,KCNF1,MAP4,SCAMP5,NF1,P2RY1,NLE1,MINDY2,RASA3,KDM4B,RBM26,ARHGEF9,DNMBP,SZT2,CHST8,SSBP2,HIRA,VGF,VSNL1,SPHK2" Drug 266_DN (+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ANK2,APBB2,SLC4A4,KALRN,CAMK2A,CAMK2B,ARHGAP33,CHN2,CLCN3,SULT4A1,CSF1,ARHGEF4,KLHL3,FAM13A,CDKL3,EYA1,OLFM1,FOLR2,PDLIM5,NSG1,GRM2,ADAMTS6,ATXN2L,VSIG4,C2orf72,MYO7A,PALM,MASP1,C1orf109,MARCH1,ENOX1,RASGRF1,GAL3ST4,NMNAT2,UNC5B,TROVE2,ANKRD12,VIPR2" Drug 6742_UP Carbachol [51-83-2]; Up 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SYN3,NME5,C1QTNF3,SEMA6A,ALK,APOC1,CFAP410,CACNA2D2,CSF1R,SPOCK3,DTNA,EDIL3,HIPK3,NRN1,FGF1,FGFR1,ALDH1L1,CSDC2,PRUNE2,ELOVL5,MX1,CLDN11,LRRN3,PTPRB,CCDC40,ZMAT4,GSTCD,TCP11L1,ZFP30,CNKSR2,ANKRD6,SNCA,HIF3A,TK2,TNS1,RUNDC3B,EPM2A,DPF3" Drug 2948_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "MTUS1,BEGAIN,APOC1,AZGP1,RCHY1,CREM,DZIP3,CNNM1,C3orf18,RASGRP2,FER,AGAP2,NEU3,GFER,SPACA9,ATXN2L,LSS,AFDN,GIT1,PLCB2,PLCD1,PLCL1,CEP41,PTPRN2,SBF1,FAM214B,SNCA,ZHX3,CDK19,LHPP,MTCL1,EXOC7,PDLIM2,TRIM2,UBTF,SLC17A7,ADAMTSL3,TIGD6" Drug 5537_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BEGAIN,PRX,PLA2G4C,DNAH17,CFLAR,SCAPER,CD86,RIMS2,MAML1,TMCC2,EPB41,HPCAL4,ERAP1,GNAO1,GPER1,GUCY1A1,KCNN1,LIG4,MAP4,MBD1,POLG,PPARA,ELOVL2,C1orf54,EMID1,ZNF821,SYBU,FAM214B,ARHGAP26,CEP68,PLCB1,KIAA0930,DICER1,TRO,ZNF24,SPHK2,HPS4,KCNAB1" Drug 5243_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,ADRA1D,PLA2G4C,STX16,CFAP410,HAP1,QKI,ARHGEF4,USP6NL,DCAF8,RASSF2,TBC1D5,MFAP3L,SLC12A6,EGFR,PRELID3A,SRCAP,GNG4,PCLO,KCNH2,NF1,PRKAR1B,PRODH,TCP11L1,RPS6KA2,FBXO11,SLC9A5,BTBD7,SNCA,KDM4C,THSD1,ST5,PCDHA6,PCDHA5,CDK20,KCNK12,EPM2A,ST7" Drug 4356_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,APLP1,SLC2A11,ARHGEF7,MTMR3,GYG2,CA4,FOXN3,ASIC3,PLEKHB1,B4GALT6,PICK1,CPS1,DMPK,EIF4G2,TNK2,VPS13B,VPS26C,SCARA3,GAD1,MSL3,SPACA9,MAP4K5,ICA1,KCNN2,KIT,MMP16,NF1,CNOT4,NLE1,C1orf54,TCP11L1,RASA3,ARHGAP26,THSD1,ST5,PARD3,EVI5" Drug 6930_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,AP2A2,SEMA6A,APBA2,APBB2,ARHGDIG,CDK13,ATP6V0A1,WHRN,AKAP12,CSF1R,VCAN,PDE4DIP,HDAC4,SPOCK3,DTNA,EGR3,OGA,FYB1,ZNF44,INPP5K,GLI2,TDRKH,C2orf72,MATK,ADAM11,MEIS1,MMP16,MTRF1L,WDR25,RBM34,IQSEC2,CLSTN2,CEP68,TK2,VLDLR,PARP11,FAM13C" Drug 1782_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; HL60; HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,GYG2,CA12,CHN2,EPS15L1,RAB26,CRMP1,PPP6R2,ZNF337,DAPK3,EXOG,KAT8,BAIAP2,TRMO,POMT1,PCDH17,CACFD1,NXPH3,ATXN2L,TJAP1,KIF5A,LIG4,NF1,NRCAM,NTRK3,SETD4,DEF8,RGS12,RNASE1,FNDC3A,CCDC92,SLC11A1,KBTBD4,ELMO2,TEX2,PCDHA5,TRPM2,NLRP3" Drug 2909_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "AGT,AMPD3,CDC42BPA,APBB2,NCOA1,CA8,CACNA2D1,SEPT7,DCLK1,EPS15L1,PICK1,SHANK1,AFF2,SEPT9,ALDH1L1,GLYR1,GNG4,VSIG4,HNMT,TJAP1,AFDN,ADAM22,TAGLN3,PDE4D,NLE1,PLCD1,CEP41,EMID1,CNKSR2,EPN2,SLC11A1,DOK5,ZC3H13,TROVE2,TNS2,UGT8,PCBP4,ADAMTSL3" Drug 3531_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "APBA2,APBB2,APLP1,DDO,FAM131A,ADAM23,TAOK2,CREM,PDE4DIP,ARHGAP24,TMCC2,DTNA,FRY,RRAGB,DLC1,ZNF589,FGFR1,SEPT9,RUNDC3A,GLYR1,GSN,TJAP1,LAMA2,MATN3,MSI1,ADAM22,NF1,NTRK3,CDK18,PPP5C,ELOVL2,GAL3ST4,RGS12,TCP11L1,ST6GAL1,SMG6,TNS1,KCNAB1" Drug 3136_UP Trapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,AMPH,APBB2,PPP4R4,THSD7A,CAMK2B,CRY2,DZIP3,GPRASP1,SPOCK2,E2F5,ETV1,F5,FGFR1,TMEM8B,ZNF276,GLYR1,ICA1,TJAP1,MAPT,AFDN,MMP16,CNOT4,PFKFB2,PLCD1,PRPH,BCAS3,PTPRN2,MAP6D1,MAPK12,ZNF821,SNCA,SYT5,CRTC1,TRPS1,FAM155A,FLRT2,SPHK2" Drug 4187_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SYNJ1,MYRF,LARGE1,STOML1,RAB26,HOMER3,AKAP5,HAPLN1,CRY2,SPOCK2,DNAH9,DYNC1I1,DTNA,ING4,PDLIM5,CAMKK2,PCDH17,STON1,IRF8,MEF2C,NECAB2,PTPRN2,GAL3ST4,RGS3,SUPT20H,PREX2,SLC2A5,SLC14A1,SMARCD3,SNCA,DOK5,SOX15,ADGRL3,R3HDM1,TPM1,PRDM10,SLC17A7,EPM2A" Drug 1753_UP Noscapine [128-62-1]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,ACTN1,NDRG2,ADCY6,ADORA1,CDK10,NRP2,CD86,IQCK,ARMC8,CREM,OSBPL3,DMTF1,DPH1,FAM13A,ING4,SEC23B,TRMO,ATP2C1,RUNDC3A,ACOT7,TJAP1,AFF1,NEFH,NELL2,NPY,PDE1C,PDE4B,PTK2,ARHGEF40,CCDC88A,TMCC1,DOP1A,THSD1,VIPR2,LAT2,ZNF142,AAAS" Drug 5412_DN Clebopride maleate [84370-95-6]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "RALGAPA1,EPB41L5,FAM131A,BCAS1,CASK,SLC4A4,SYNJ2,TPP1,QKI,RCHY1,BAG4,SH2B1,CRY2,PPP6R2,TBC1D5,KIAA0586,DBT,DTNA,CNNM1,CELSR3,ING4,ANKMY1,EZH1,EFCAB2,SPACA9,HNMT,KCNH2,IPO5,NF1,ZDHHC14,TCP11L1,ASAP3,PLCB1,SLC44A1,VGF,EVI5,ST7,KAT6A" Drug 4252_DN Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "PDE8B,ATP1A3,ADGRB2,BAIAP3,HOMER3,RCHY1,SGSM2,DTNA,PLXNC1,IRAK4,IQCG,ALDH1L1,RUNDC3A,GRM8,HNMT,KCNN1,AFF1,ADAM22,MYO7A,NF1,CNOT4,NOVA2,RETREG1,FBXW7,ZFP30,FRMPD1,ASAP3,KANSL3,SNCA,DOK5,ASTN2,DNAH7,VLDLR,LAT2,ZNF45,SPHK2,KCNAB1,UBE3B" Drug 6089_DN Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,APBA2,GAS7,ARHGDIG,DNAH17,MARK4,HAP1,CAMK2G,LHX2,FAM189A2,TBC1D5,MFAP3L,DTNA,HIPK3,ING4,C3orf18,BAIAP2,GFER,POLL,RNFT2,MAP4,MSI1,SLC11A2,RETREG1,MAPK7,TMEM104,ZSCAN2,RAD51D,SH3BP2,KIF13A,KDM4B,ST5,VPS13A,MCF2L,EXOC7,TK2,TPM1,VIPR2" Drug 5739_UP Cytisine (-) [485-35-8]; Up 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BEGAIN,TRMT9B,APC,N4BP2L1,BMPR1B,CBS,PLEKHB1,RAB26,HOMER3,CRMP1,NCOR2,ABCG1,DAPK3,SPOCK2,EXOG,HIPK3,MTSS1L,ZNF549,SIGLEC8,SYT17,CPLX2,GNAO1,LPAR4,ATXN2L,IL6ST,JAK2,PDE4D,PPP2R2B,ZCWPW1,NEK11,SLC4A3,ZSWIM8,MCF2L,DOCK9,R3HDM1,AMACR,RPRM,KCNAB1" Drug 3018_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "C3orf14,ANK2,APAF1,APBB2,NCOA1,ATP2A2,AZGP1,SOCS6,FAM149A,CSNK1E,TM9SF4,KIAA0753,HIPK3,FAM13A,MBNL2,AASS,ZNF589,FLT1,CAMKK2,INPP5K,ALDH1L1,KIF2A,MAP4,GIT1,NNAT,CNOT4,ZDHHC14,TRIM68,RGS3,ZFP30,SH3BP2,SNAP25,SPTAN1,CDK20,TRO,UBTF,XRCC4,PHTF2" Drug 2756_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,KIAA1324,AK2,SPARCL1,APBA2,ST3GAL5,AKAP5,CREM,SH2B1,DCAF4,DBT,TNK2,HSD17B14,DLC1,FER,GCNT2,GFER,GPD2,TDRKH,ELOVL5,ITPKB,KHK,PPP5C,MAPK10,ZDHHC14,FAM214B,SLC11A1,ZBTB43,CAMTA2,ST5,TTBK2,TK2,UCHL1,LAT2,ZNF23,ZNF45,SLC30A3,EMSY" Drug 1534_DN Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASPHD1,NDRG2,APBB2,CDK10,KIF1A,ADAM15,GYG2,VAX2,SULT4A1,CREM,DBT,TMCC2,DNM1,RCAN1,DTNA,CDKL3,VPS26C,PDLIM5,CNTRL,NFYA,OGG1,STRN3,PRKACB,WDR25,NEK11,ZNF331,SBF1,ZNF821,ANKRD6,PPP4R3A,UNC5B,LHPP,PLCB1,ARC,TNS2,PCDHA6,XRCC4,SPHK2" Drug 3074_UP Tyloxapol [25301-02-4]; Up 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "BIN1,ANK2,APBB2,APC,SEMA4G,ARHGDIG,PDE8B,FUBP1,BAIAP3,CA12,SLIT2,ABCG1,CSNK1E,ARHGEF4,DCAF4,C3orf18,ARMCX1,FGF12,FGFR3,BAIAP2,FHL1,GABRG2,AHDC1,GRIK5,PADI2,KCND1,MAP4,MGAT3,MYO6,MYO7A,NF1,NRCAM,FAM214B,TRIM2,PCDHGA10,FAM155A,LMF1,KLC2" Drug 1101_DN catechin; Down 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG3,APC,CDK10,NCOA1,MTMR2,ZNF337,SPATA2,SGSM2,EXOG,SUGP2,MBNL2,FGFR1,NBEA,MALT1,PRRC2B,KIF2A,MBP,SETD4,OGG1,PDCD2,MRPS18A,ROBO1,MAP6D1,SAFB,ATXN7,GALNT10,SUPT20H,CHD9,DHX30,SPTAN1,CDK19,TRIM2,DOCK9,OBSL1,NR2C2,TRIO,TSN,ZNF24" Drug 2197_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "SRPX,APC,GAS7,CDK10,CACNA1I,PDE4DIP,TBC1D5,HIPK3,ELN,C3orf18,ANKMY1,BAIAP2,AGAP2,TMEM8B,PCDH17,TDRKH,STON1,RASSF8,KCNJ5,KIF5A,L1CAM,OGG1,PDE4A,PFKFB4,PNMA3,FSD1,MASP1,RELN,BEND5,PREX2,RBM34,ATP10B,TCF4,CRTC1,TPM1,LMF1,PLSCR4,SENP7" Drug 2358_UP Flutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADORA1,AMT,ANK2,APBB2,APOC1,SEMA4G,ARRB1,MARK4,NUMB,KIF1A,SYNJ2,MYRF,LDLRAD4,CD38,CHN2,SEC31B,SH2B1,ARHGEF10,SPOCK3,RCAN1,E2F5,MRNIP,ZNF589,MAN1B1,INPP1,IPO5,ZNF862,NTRK2,SUGCT,SCN2B,TSPYL2,ATP10B,ZC4H2,EXOC7,DOCK9,TNS2,PARD3,KAT6B" Drug 2549_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ASIC1,APC,CDK10,NCOA1,CAPN3,CBFA2T2,ARHGAP33,PLAA,STOML1,CREM,SIPA1L1,ZNF337,DTNA,FEM1B,PLXNC1,MRNIP,RASGRP2,ZNF589,ANKFY1,CGREF1,RAB40B,MAP4K5,NCKAP1L,MEF2C,NF1,PLTP,PPP5C,ZDHHC14,RGS3,FAM214B,BTBD7,UHRF1BP1L,STX1A,THRA,CDK20,UBE3A,PLPPR2,LMF1" Drug 1204_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ADRA1D,ADGRF5,GAS7,BCAS1,MARK4,STX16,MPDZ,CHN2,TPP1,AKAP7,PARD6A,SPOCK3,HIPK3,EIF5,MRNIP,FGFR1,AFF2,CSDC2,ICA1,SCIN,MAP4,NF1,CNOT4,POLG,WDR25,CNTLN,PTN,TMEM231,GAL3ST4,ATXN2,PEX26,BTBD7,KDM4C,EXOC7,WNT7A,SPHK2,HPS4,AAAS" Drug 3323_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,BRAP,AGT,NME5,BIN1,ATP1A3,CFAP410,ARHGEF1,CLGN,CRLF1,TAOK2,RAB33A,CLTB,LY86,COL9A3,NECTIN3,DMPK,CELSR3,PLXNC1,ZNF589,FGF13,SIGLEC8,GFER,MARK1,ZNF862,NF1,NOVA2,CCDC40,ZDHHC14,TRIM68,KLHDC8A,SH3BP2,ST6GAL1,SLC9A5,SNCA,KDM4B,TAL1,TRPM2" Drug 6801_UP Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG3,ADCY6,AMT,DNAH17,ASPA,CACNA1I,NFS1,VAX2,SMARCAL1,CREM,CRMP1,AATK,PDE4DIP,JAKMIP2,EDNRA,PHC2,MRNIP,LPAR4,GPER1,CACFD1,TJAP1,MMP16,ZNF862,NTRK2,PLCD1,SLC25A23,PPP5C,EMID1,RASA3,ZSWIM8,IQSEC2,TSPYL2,VPS13A,ZNF34,TNS1,LAT2,ZNF24,TIGD6" Drug 5019_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,APBA2,PPFIA3,CAMK2G,KRIT1,CBFA2T2,LHX2,RAB28,NECTIN3,INTS1,ZNF804A,MFAP3L,ENO2,TAOK3,FHL1,GAA,INPP5K,MSL3,GPR37,HSF2,IL6ST,MAP4,MATK,NF1,SLC11A2,SLC25A23,PMP22,LRP12,PPP2R2B,SBF1,SH3BP2,CPEB3,EPN2,CDK5RAP2,SS18,TRIM2,CRTC1,HPS4" Drug 2288_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NDRG2,GAS7,PRX,ARHGDIG,MARK4,SLC4A4,ATP2B2,CAMK2B,RUNX1T1,USP2,ASIC3,CNN3,CNTFR,CSF1,CSF1R,DMPK,EIF4G2,SCARA3,PDLIM5,GPR162,MAP4,MEF2C,MGAT3,MSR1,NTRK2,PALM,PDE4B,PFKFB2,SAMD9,PTPRH,C1orf54,DDN,ATP10B,PHLDB1,EXOC7,CRTC1,TRPM2,DNALI1" Drug 7526_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "NME5,APOC1,PPFIA3,NCOA1,ARHGEF1,ARHGAP22,CLTB,RAB26,NRG2,CNTNAP2,TUBD1,EZH1,USP19,CRCP,GLI2,IL12A,INPP5B,MMP17,ZNF862,NPR2,PALM,PTPRN2,SH3TC2,GAL3ST4,MRAS,SLC4A3,KDM4B,SPTAN1,ARHGEF9,SYT1,IQCE,CHST5,HIRA,PDIA2,WRN,ZNF74,NDRG4,HPS4" Drug 7542_DN Ald1.1-H_000455; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "ABHD6,AK2,SEMA6A,CDC42BPA,MARK4,ATP6V0A1,BCL7A,PLEKHB1,DBN1,DBT,EGFR,MBNL2,CINP,ATP2C1,ERAP1,TXNL4A,CACFD1,MAP4K5,IRAK3,RASSF8,ITPKB,MAP4,MAPT,CCSER2,PRKAR1B,RAD51D,RGS12,ZFP30,RBM34,ZHX3,CLSTN2,CEP68,TMPO,PARD3,PLPPR2,VGF,KAT6A,SMIM8" Drug 4625_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.22E-04 1.00E+00 7.02E-03 7.90E-02 38 198 "KIF1A,NRP2,IL33,CFAP410,THSD7A,HIP1R,SH2B1,ARHGEF10,PDE4DIP,RIMS2,INTS1,MFAP3L,DRP2,EIF4G2,COQ7,APC2,FAM198B,CORO2B,HPCAL4,ERGIC3,ICA1,KIT,P2RX7,PDE4B,PIK3R1,ENOX1,TCP11L1,RTN1,TRAPPC13,ARHGEF40,OGDHL,SNCA,FAIM2,ASTN2,SPHK2,PHTF2,SENP7,JPH3" Drug 4554_UP Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.25E-04 1.00E+00 7.04E-03 7.93E-02 35 178 "OSBPL1A,CDK13,NRP2,SYNJ1,EPS15L1,ABCG2,HOMER3,CREM,SH2B1,CSF1R,DAPK3,ZNF804A,MFAP3L,EDN1,ST3GAL6,ZNF589,FGFR1,B4GALNT1,GCNT2,CACFD1,ELOVL5,FAM69A,KCNB1,MX1,NCF2,OXTR,KHDRBS2,RGS12,HSPA4L,CNKSR2,SOX15,JMJD6,ZEB1,PCDHGA10,EVI5" Drug ctd:C540355 1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one CTD 8.31E-04 1.00E+00 7.09E-03 7.99E-02 63 373 "ACTN1,XKR4,ADRB2,PCDH19,DPP10,IGDCC4,CADPS,CCK,NRXN3,TPP1,PCYT1B,COL4A5,HAPLN1,CSF1,IPCEF1,GALNT9,SV2B,SPOCK3,HS3ST2,SHANK1,EGFR,CERCAM,ELN,FGFR1,FGFR3,AMOTL2,FLNC,PDLIM5,GAD1,CPLX1,STON1,IGFBPL1,TJAP1,ITGA7,KIF5A,TTYH2,NPR2,SERPINI1,PTPN13,PTX3,ENOX1,KIRREL1,LRRK2,SMPD3,PPM1E,SLC12A4,NAPB,FAIM2,ITPRID2,ST5,SYN1,SYT1,CAMTA1,PDLIM2,PCDHB9,NACC2,TNS1,VSNL1,ANKS1B,TMEM178A,RGS7BP,MSRB3,NETO1" Drug 3945_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.56E-04 1.00E+00 7.29E-03 8.21E-02 36 185 "CFLAR,KRIT1,LRRFIP1,LHX2,SLC4A8,SMARCAL1,JAKMIP2,ZBTB24,RHOBTB1,SACS,ANKRD46,IRAK4,ARMCX1,TBC1D16,ZNF589,CNTRL,RNFT2,FAM69A,ITPKB,JAK2,THYN1,PDCD2,PIK3R1,NLE1,POLG,ZSCAN32,ROBO1,MAP6D1,TMCC1,SPATA7,CEP68,KANK1,ZC3H4,FAM208A,ZNF23,HPS4" Drug 831_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.56E-04 1.00E+00 7.29E-03 8.21E-02 36 185 "NDRG2,OSBPL1A,CFLAR,ST3GAL5,ARHGEF2,MAGI1,CLGN,CREM,SIPA1L1,CTH,ZNF337,MFAP3L,MBNL2,ARMCX1,FAM49B,ATP2C1,CNTRL,GRB10,GRM8,FICD,INPP1,AFDN,MORC4,RPS6KA2,HSPA4L,SH3BGR,PPM1E,FNDC3A,NLGN1,ERC1,TSPYL2,LHPP,PLCB1,BEX4,PARD3,VLDLR" Drug 2916_UP Letrozole [112809-51-5]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.56E-04 1.00E+00 7.29E-03 8.21E-02 36 185 "MTUS1,AMPD3,BIN1,BMP7,LDLRAD4,SULT4A1,RAB26,SIPA1L1,TMCC2,PHC2,CELSR3,ELN,STX2,KAT8,FLT1,ZNF44,MSL3,GSN,VSIG4,IL6ST,AFF1,AFDN,ADAM22,ZNF862,P2RY1,MARCH1,RGS12,PBRM1,SEC14L1,SH3BP2,ANKRD6,ZHX3,DDN,MTCL1,SLC44A1,AMACR" Drug 4542_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.56E-04 1.00E+00 7.29E-03 8.21E-02 36 185 "ACTN1,ADRA1D,CDK10,PTCH2,CACNA1G,BAIAP3,CPS1,AKAP12,CTH,EDN1,ING4,NRN1,FGFR1,AMOTL2,CINP,PDLIM5,FYB1,ERAP1,FERMT2,SOX21,PDE1C,PDE4D,NLE1,GRAMD1C,PRPH,SEMA6D,RASA3,SH3BP2,PDZD2,HECW1,PHLDB1,TBCEL,GPR161,R3HDM1,TRIO,ZNF24" Drug CID006857352 AC1OAGFW Stitch 8.56E-04 1.00E+00 7.29E-03 8.21E-02 36 185 "OSBPL1A,MTMR3,MTMR2,CAST,MTMR7,CLTC,CYBB,ARHGAP32,ZFYVE16,PDCD6IP,EGFR,GPHN,GRB10,KCNN1,KCNN2,KCNN3,MAT2A,NCF2,PIK3C2A,PIK3R1,PBRM1,S100B,SBF1,HSPA4L,SGK1,NSFL1C,ARHGEF9,PLCB1,MCF2L,TIAM1,MTMR14,TSC1,SGK3,UBC,GORASP1,OSBP2" Drug ctd:D005947 Glucose CTD 8.65E-04 1.00E+00 7.37E-03 8.30E-02 200 1428 "ACHE,NDRG2,ADRB2,MTA3,AGT,WDR35,SPARCL1,OGT,LRCH2,APBB2,APC,PLA2G4C,ZBTB10,ATP1A1,SLC2A11,KIF1A,AZGP1,SEC11C,SYNJ1,FUBP1,AP1M1,SGCE,CALM1,PTBP2,SLC25A14,HIP1R,CBS,ARHGEF1,CCPG1,FOXN3,CNOT8,QKI,CNR1,ZNF521,NECTIN3,CRMP1,RNF14,NCOR1,OSBPL3,CYBB,GAPVD1,MAML1,DBI,DBN1,B3GAT3,DDX46,NR1D2,DMTF1,CASP8AP2,DNM1L,E2F5,EDN1,EDN3,EIF4G1,EIF5,ING4,CERCAM,EMX2,ENO2,LRRC17,RABEPK,ERBB2,EXTL2,REEP2,RACK1,KAT8,MED12L,MAD2L2,ATP5PD,MEX3B,FOXO3,SLC37A3,NELFCD,NBEA,GAD1,IQGAP2,MTHFD2,GCK,ARFIP1,PPARGC1A,TXNL4A,DBF4,GLUL,KDM2B,FERMT2,GPD2,STON1,GRIA2,ATE1,GSN,LINGO1,SLC2A6,HBA1,MIER3,ACOT7,HP,IFI16,IGF1,IL6R,IL6ST,JAK2,KCND2,KCNH2,KLHL23,LAMP2,MAP4,MOV10,NCF2,NFE2L2,NPY,SLC11A2,NUCB2,OPA1,P2RX7,PAX6,PRTG,ABCB1,PIK3R1,PKM,PLCB2,SMOX,PPARA,PRKCB,MAPK3,MAPK9,BCAS3,PTCH1,PTK2,PTN,OXR1,RET,GTDC1,RGS12,PBRM1,RNASEL,RPS20,HUNK,CLIP1,RXRA,SARS,GALNT10,MRAS,COPZ1,RASA3,SCAF8,SGK1,SH3BGR,SH3BP2,CHD9,SLC2A5,EPN2,LIMS2,SEPHS1,SLC8A1,CDK5RAP3,SLC12A2,SLC12A4,GKAP1,SNAP25,MBD5,TMCC1,KDM4B,DOP1A,SPP1,DBNDD2,SPART,CLASP2,ADHFE1,NSFL1C,VPS13A,PLCB1,SYP,SYPL1,SYT1,MGRN1,DMXL2,ARHGAP9,SIRT1,SLC44A1,ACTR6,TLR4,KAT6B,TP53BP1,NPL,TSC1,TUBB2A,UCHL1,FLRT2,TOM1L2,WIPF1,CLDND1,NDRG4,INTS3,SLC30A3,TUBA1A,NLRP3,NHSL1,ZDHHC20,AAAS,ST8SIA2" Drug CID000000482 InsP5 Stitch 8.81E-04 1.00E+00 7.50E-03 8.45E-02 17 66 "ADRA1B,RIPK1,CA4,CLTC,IP6K1,IP6K2,IP6K3,HBA1,DDX19B,INPP1,ITPKA,ITPKB,PGAM2,RASA3,ARHGAP26,NSFL1C,SYT1" Drug 1058_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.82E-04 1.00E+00 7.50E-03 8.45E-02 34 172 "ABHD6,ST3GAL5,CBFA2T2,AKAP12,GIT2,OPTN,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,FYN,RAB40B,STON1,PADI2,FAM69A,MXI1,NEK1,PCDH9,PKIA,PRPH,SH3BGR,SH3GL3,PPM1E,WDR47,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,SSBP2,REEP1" Drug 1778_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "ARNTL,ATP2A2,CAST,IPCEF1,GAPVD1,ZFYVE16,MATR3,GIT2,DBT,KIAA0753,EIF5,COPS4,DENND4A,ACSL4,GLUL,PRRC2B,KTN1,MBD1,NEK1,SMIM7,ZNF426,MAPKAP1,RDX,UBR7,PCMTD2,ATXN2,CHD9,PPP4R3A,ARHGEF40,KBTBD4,NXT2,TTBK2,ANKRD12,EXOC7,DICER1,EVI5,MPPE1" Drug 4268_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "MTUS1,PKP4,ADAM15,SYNJ2,SPAG9,SOCS6,CLCN3,DAPK3,DBT,SPOCK3,EGFR,MBNL2,FER,SPIN1,PCLO,RASSF8,AGFG1,IL6ST,MAP4,TM6SF1,NFIX,PDE1C,PIK3R1,PLEC,STRN3,PRKAB2,SLC25A36,KIRREL1,SEC14L1,SPTAN1,PLCB1,DICER1,TMPO,EVI5,KCNAB1,UBE3B,FXR1" Drug 7556_UP vinblastine sulfate; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "ACTN1,BRAP,BIN1,PKP4,NUMB,CCNT1,PLAA,CLCN3,CREM,AKAP12,SGSM2,TNK2,EZH1,FGF1,AMOTL2,SRCAP,FERMT2,PRRC2B,IL6ST,FAM69A,SETD4,OGG1,PDE1C,PDE4A,MBOAT7,SAFB,ASAP3,ARFGAP1,CLASP2,CAMTA2,PHLDB1,COBL,TMPO,CABIN1,HIRA,UBE3A,LAS1L" Drug 2292_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "CDC42BPA,APC,APOC1,PPFIA3,CDK13,MARK4,CFLAR,QKI,HOMER3,PUM1,DNM1,EIF5,ING4,ZNF589,PRELID3A,GNG4,CNTRL,ACOT7,IL6ST,INPP5B,PLXNB1,PRPH,SLC25A36,RNASEL,ZNF821,SH3BP2,FAM214B,BTBD7,POGZ,SS18,ST5,ELOVL4,ASTN2,TK2,TMPO,GDPD5,RNF170" Drug 4449_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "AMPD3,BIN1,CDC42BPA,APAF1,APBB2,APOC1,SEMA4G,ATP6V0A1,ADGRB2,LHX2,COL9A3,NRG2,HIPK3,CELSR3,NCALD,CGREF1,SHISAL1,KCNJ5,MN1,ZNF862,OPRL1,PFKFB4,PLCB2,WDR25,BEND5,SAFB,ATXN7,MRAS,PPP4R3A,ARHGEF40,SLC9A5,SMG6,CHST8,VIPR2,TRIM9,TFIP11,PHTF2" Drug 1589_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "EIF4G3,CFLAR,BMP7,SYNJ2,CA12,CD86,CD38,TAOK2,RAB28,LETMD1,CRMP1,PPP1R16B,DMTF1,MBNL2,EGR3,RASGRP2,IGSF6,VPS26C,CACFD1,PADI2,TJAP1,NELL2,NTRK2,NTRK3,SMOX,PTX3,RNASE1,FAM102A,AMBRA1,ARHGEF40,CCDC88A,SLC11A1,KDM4B,STXBP1,GORASP1,FLRT2,SLC17A7" Drug 5620_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "KCNAB2,APC,CDC14B,ADAM23,CFLAR,KSR1,KCNAB3,CNTFR,PHF14,GIT2,EDN1,EGFR,EGR3,CORO2B,AGAP2,POLL,CNTRL,ATXN2L,HLF,TAGLN3,NF1,NOVA2,NTRK2,CDK18,PFKFB2,PURG,PRKCB,CNNM2,PTPRE,MRAS,LIMCH1,KIF13A,KDM4B,ZHX3,PHLDB1,SPHK2,SEMA3B" Drug 1153_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "ABHD6,APAF1,APBB2,ARNTL,PDE8B,NCOA1,ST3GAL5,KYAT1,LHX2,CREM,DOCK4,ZFYVE16,FAM13A,ENO2,ETV1,EXTL2,F5,PCYOX1,ADAM28,SLC2A6,PADI2,MEF2C,ZNF862,NEK1,SERPINI1,RETREG1,PMP22,MINDY2,PPP5C,RPS6KA2,ANKRD6,ZC4H2,RGL1,STXBP1,PJA1,SSBP2,TRIM9" Drug 2261_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "BIN1,APOC1,CDK13,ADAM23,CLGN,CNN3,NCOR2,EDNRB,ING4,MTSS1L,PIPOX,DLC1,SCARA3,OGA,RUNDC3A,HPGDS,GPER1,GRB10,GUCY1B1,ATXN2L,C2orf72,MX1,LRRN3,PRKAR1B,C1orf54,RFX3,SEMA6D,SH3BP2,ST6GAL1,PKNOX2,PDZD2,ZSWIM8,TCF4,ICAM5,CHST5,TUBB1,VLDLR" Drug 6752_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "APC,ARHGDIG,STX16,ATP2A2,MTMR2,CCNT1,ARHGEF1,QKI,HAPLN1,DZIP3,TBC1D5,EXOG,FCF1,MTSS1L,ANKFY1,FYB1,USP19,MSL3,SCIN,KCNN1,KIF2A,MYO6,PLCD1,POLR2F,BCAS3,CNTLN,PTK2,ZCWPW1,SS18,PHLDB1,GPR161,BEX4,UGT8,OSBP2,WNT7A,KCNAB1,PHTF2" Drug 5729_UP Disulfiram [97-77-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "SEMA7A,APC,PRX,BMP7,CAMK2B,PHF14,C2CD2L,HS3ST2,RASGRP2,CDKL3,BAIAP2,FLT1,DENND2A,SRCAP,ELOVL5,KIT,MMP16,MT1M,PCSK1,PDE4D,PIK3R1,PTN,C1orf54,RASA3,HSPA4L,CPEB3,TSPYL2,ARC,COBL,SYT5,SYNE1,SLC44A1,BEX4,VSNL1,NAV3,SLC17A7,KCNAB1" Drug 6809_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "ADRA1D,AK2,ALCAM,APOC1,ARRB1,ATP6V0A1,CFLAR,CARS,PLEKHB1,TAOK2,SH2B1,SIPA1L1,GREB1,RIMS2,PPP6R2,DTNA,EIF4G2,ZNF589,FER,FGFR1,FAM49B,OGA,FYN,INPP5K,TXNL4A,NCAM2,RETREG1,SEC14L1,ZKSCAN3,ZBTB43,CLASP2,TROVE2,TRIO,MPPE1,EPM2A,ST7,PHTF2" Drug 2919_DN Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "NDRG3,BRAP,ADRB2,PPFIA4,ZBTB10,CFLAR,SCAPER,KRIT1,SLC16A4,ZMYM4,QKI,CPS1,ENO2,ZNF589,FGFR1,SEMA4D,FLT1,POMT1,ATP2C1,SESN1,MAN1B1,IL6R,JAK2,LSS,PIK3C2A,MINDY2,SEC14L1,SLC6A8,KDM4B,SPTAN1,JMJD6,ANKRD12,DNMBP,TPM2,UBE3A,XRCC4,MAP3K12" Drug 5955_UP estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-04 1.00E+00 7.50E-03 8.45E-02 37 192 "ADCY6,ALK,BEGAIN,CFLAR,SCAPER,SGCE,BAIAP3,CBFA2T2,SCARB1,QKI,RCHY1,SH2B1,LRIG1,TBC1D5,C2CD2L,DTNA,EGR3,STX2,ERCC2,ZNF589,FHL1,POLL,GPD2,MAP4,ZNF862,NF1,RELN,RASGRF1,ZDHHC14,SLA,SLC2A5,SLC44A1,CHST5,TRIO,UCHL1,LAT2,ZNF24" Drug CID000003837 AC1L1GTT Stitch 9.04E-04 1.00E+00 7.56E-03 8.51E-02 43 233 "AGT,CFLAR,CACNA1B,CACNA2D1,CALM1,CAMK2A,CAMK2B,CAMK2G,KRIT1,LRBA,MYEF2,EDN1,PPP1R1B,CAMKK2,PPARGC1A,GRB10,GRIA2,GRIN2C,GRIN2D,MYLK2,JAK2,KCND2,KCNK3,MBP,MEF2C,NEFM,P2RX7,P2RY1,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PTK2,PTPRN2,RGS4,RYR3,SNAP25,SYN2,TIAM1,CABIN1" Drug 2567_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,AP2A2,MTUS1,PKP4,ZSCAN18,HIP1R,CRY2,SLITRK5,DZIP3,PTK2B,SEC23B,GALC,TMEM8B,ZNF276,GPD2,STON1,CACFD1,GSN,KCNN1,LIG4,SAMD14,PDE4B,PFKFB2,PLCD1,STRN3,CNNM2,PTPRN2,C12orf49,SLC11A1,SS18,ARHGEF9,RPGRIP1L,ICAM5,PIK3R5,TUBB1,LMF1,CLIP2,PHTF2" Drug 5433_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,ADRA1D,ALCAM,LTBP4,APC,EPB41L5,SCAPER,C5,CLCN3,SH2B1,MAML1,GIT2,PLXNC1,EIF4G2,HSD17B14,ANKMY1,FGFR1,SEMA4D,DISC1,RAB30,POLL,GPER1,ATXN2L,HNMT,KIF2A,KPNA5,MPP2,ADAM22,LYRM9,SETD4,MAPK7,TMEM104,MSANTD2,ASAP3,PPP4R3A,PLCB1,EXOC7,SPHK2" Drug 1989_UP Antipyrine [60-80-0]; Up 200; 21.2uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "CDC42BPA,APBB2,CDC14B,SEMA4G,BCL7A,CFAP410,KRIT1,P2RX6,ARHGAP33,SRSF11,CTH,KIAA0586,DAPK1,SPOCK2,PLXNC1,IGSF6,CD320,ACSL4,SPIN1,GPR12,SLC2A6,MYT1,SETD4,ZNF426,VPS13C,MSANTD2,MRPS18A,NUBPL,KBTBD4,KDM4B,ATP10B,POGZ,LARP4,MGRN1,ZEB1,TNS1,HIRA,VIPR2" Drug 2566_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "CDC14B,CACNA1I,HOMER3,ARMC8,FAM149A,VCAN,CDON,EDNRB,FCF1,ELN,RASGRP2,ERAP1,SEPT9,SRCAP,MAN1B1,ATXN2L,KHK,MEF2C,SCAMP5,MID1,AFF1,AFDN,MYO6,NTRK2,NLE1,MAPK7,PTN,MRAS,LIMS2,SLC11A1,TBL1X,THRA,UBTF,LMF1,XRCC4,KCNAB1,UBE3B,KAT6A" Drug 7284_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APC,CDK10,ALDH7A1,KIF1A,CFLAR,CLTB,HOMER3,PDE4DIP,SLITRK5,RUSC2,EDNRA,BAIAP2,AGAP2,EFCAB2,ZNF44,GAD1,FAM69A,INPP5B,KPNA5,LIG4,MAPT,SCAMP5,PALM,PDE4B,MAPK7,PTCH1,NCBP3,SCN8A,SEC14L1,ZNF821,SH3BP2,AMBRA1,ARHGEF40,THSD1,RUNDC3B,WIPF1,WNT7A,EPM2A" Drug 4649_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NME5,AMT,KCNAB2,CFLAR,LHX2,NCOR2,CSNK1E,VCAN,PDE4DIP,DCAF4,TBC1D5,RUSC2,EDNRA,FAM13A,BAIAP2,CAMKK2,INPP5K,POLL,TDRKH,TJAP1,NF1,PLCD1,SLC25A23,FSD1,PRKAR1B,TMEM231,SAFB,FNDC3A,ELMO2,ERC1,SPTAN1,ELOVL4,BHLHB9,LMF1,WIPF1,HPS4,UBE3B,PHTF2" Drug 2012_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APOC1,BCL7A,ST3GAL5,PTBP2,CLDN10,ARHGAP33,CRY2,ARHGEF10,SOCS5,ARHGAP32,CELSR3,IRAK4,VPS26C,ANKMY1,FYB1,CACFD1,ITGA7,KHK,KIF5A,MAP4,NF1,CCSER2,PLEC,RET,GSTCD,TCP11L1,HUNK,SCP2,AMBRA1,KBTBD4,ELMO2,MAPKBP1,SPART,CRTC1,PARD3,NPL,CHST5,ZNF23" Drug 444_UP clofibrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,SYT13,CASK,ARNTL,ARRB2,SLC4A4,EIF4G3,ATP6V0A1,CACNA1I,CAMK2G,ARHGEF2,CNTN1,GREB1,B3GAT3,TMCC2,DTNA,EPHB1,TBC1D16,FGFR1,FHL1,FLNC,RAB40B,ICA1,JAK2,KHK,NTRK3,PLXNB1,FSD1,RNASEL,SH3GL3,SLC11A1,ELMO2,ZKSCAN3,SNCA,TMCC1,RGL1,EXOC7,NDRG4" Drug 4705_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APLP1,BCAS1,MARK4,SCAPER,MTMR2,GYG2,PTBP2,FAM189A2,NCOR2,JAKMIP2,HSD17B14,DENND4A,FYN,ERAP1,GFER,MSL3,GNG4,TDRKH,CNTRL,ITPKB,MBD1,MIA2,MPP2,ADAM22,RETREG1,GTDC1,FBXW7,VPS13A,FBXW11,RPGRIP1L,THRA,TK2,XRCC4,MAP3K12,EVI5,SEMA3B,KAT6A,TIGD6" Drug 2298_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BEGAIN,APLP1,ATP6V0A1,CACNA1A,CALB2,RUNX1T1,MTMR7,CSF1,SIPA1L1,VCAN,GREB1,RIMS2,JAKMIP2,SPOCK3,TMCC2,ERCC2,OLFM1,NXPH3,KCNB1,KHK,MID1,MSR1,P2RX7,PLCD1,PDZRN4,PTPRN2,PKNOX2,SLC6A8,DOK5,SPTB,SYP,WSCD1,TNS1,FAM155A,ZNF74,SLC30A3,ADAMTS9,JPH3" Drug 1705_UP Dapsone [80-08-0]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NCOA1,SLC4A4,ARHGEF2,B4GALT6,CNTN1,ENTPD4,SOCS5,DBT,LYPD1,EDNRA,HIPK3,PLEKHA1,INPP5B,JAK2,NEK1,NF1,NFYA,CNOT4,CDK18,PLCD1,CNNM2,GSTCD,CLIP1,PEX26,PPP4R3A,BTBD7,SNCA,TSNAXIP1,CDK19,SPART,POGZ,PRRC2C,PLCB1,SYT1,TBL1X,CHST8,KCNAB1,UBE3B" Drug 3618_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADORA1,SPARCL1,MARK4,HAP1,CAMK2B,CAMK2G,CRMP1,CSF1,SPOCK2,EDN1,RASGRP2,CAMKK2,CSPG5,GABRG2,FERMT2,INPP5B,KHK,FXYD7,NPR2,PAX6,CDK18,PDE4B,RETREG1,C19orf57,ELOVL2,PTPRN2,MARCH1,CCDC40,C1orf54,GAL3ST4,KLHL11,FRMPD1,CNKSR2,ARHGEF40,SLC11A1,ATP10B,SLC19A3,TNS1" Drug 5279_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,ADORA1,AMPD3,APC,GAS7,CDC14B,CDK13,ADAM23,MPDZ,SCAPER,CAMK2B,CBARP,SULT4A1,CSF1,RIMS2,DCAF4,MFAP3L,HS3ST2,EDN3,FRY,MTSS1L,FYB1,PRUNE2,GUCY1A1,SMAD1,PGAM2,STRN3,PILRA,KHDRBS2,KCTD17,FAM214B,KDM4B,SYT5,DMXL2,TRIO,KCNK12,NT5M,KCNAB1" Drug 2284_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "LTBP4,BIN1,PRX,ARHGDIG,MARK4,SLC2A11,CFLAR,GYG2,CACNA1G,CDH2,SULT4A1,LY86,CNTFR,WHRN,CSF1,DMPK,SPEG,GPR162,KCNJ5,KCNQ3,NNAT,PALM,PCDH9,CEP41,C1orf54,RGS4,SEMA6D,SLC2A5,OGDHL,SNAP25,PEG10,ARHGAP26,TACC1,ADGRL3,WSCD1,SZT2,FLRT2,WIPF1" Drug 1516_UP Loxapine succinate [27833-64-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,ADD2,ADORA1,ADORA2A,AK2,AMH,CFLAR,SYNJ2,GYG2,ARHGAP33,CACNA2D2,HOMER3,AKAP7,EDN1,IQCG,NEU3,GFER,TXNL4A,POLL,TDRKH,ATXN2L,ADAM22,PALM,CDK18,PURG,LRP12,MINDY2,MAPK7,MAPK10,PRODH,ZFHX4,SH3BP2,EPN2,SSTR2,STX1A,LAT2,GDPD5,NLRP3" Drug 5464_DN Adrenosterone [382-45-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AMPD2,BACH1,CFLAR,SLC4A8,ZNF337,MFAP3L,RCAN1,CNNM1,EPB41L2,COQ7,NOP56,CGREF1,INPP5K,AHDC1,TDRKH,BTN2A1,IL6R,MPP2,NF1,PTK2,RNH1,SBF1,BTBD3,ELMO2,SMARCA4,LIMCH1,MAPKBP1,RBM34,ERC1,ZBTB43,ITPRID2,PHLDB1,SATB2,CABIN1,PLPPR2,XRCC4,ZNF74,HPS4" Drug 4749_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,LTBP4,ALK,AMPH,DNAH17,MARK4,MTMR7,COL9A3,AKAP5,INTS1,DTNB,ING4,ZNF589,FGFR1,FHL1,CSPG5,ZNF44,DISC1,SRCAP,CSDC2,IRF8,TJAP1,KCNH2,MATK,ADAM22,NTRK2,NTRK3,PLCB2,PTX3,SLA,LIMS2,LIMCH1,PIK3R5,VGF,LAT2,SLC30A3,SLC17A7,KCNAB1" Drug 6525_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,SEMA6A,KCNAB2,DDO,AQP6,ARHGDIG,CACNA2D1,CNN3,CNTN1,WHRN,GREB1,ARHGEF4,DTNA,ERCC2,F5,AGAP2,TPK1,NSG1,GNAO1,HLF,MAN2A2,NLE1,PPP5C,RELN,RASGRF1,KCTD17,GSTCD,KCNIP1,SBF1,SH3BP2,SLC9A5,STX1A,JMJD6,OBSL1,HIF3A,SLC44A1,PARD3,FLRT2" Drug 3507_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AP2A2,AMPD3,ARRB1,MARK4,ATP6V0A1,ADAM15,CFLAR,GYG2,CFAP410,SOCS6,PLAA,RAB26,NCOR1,PDE4DIP,GIT2,DBN1,LYPD1,TOM1,EGFR,COQ7,KAT8,BAIAP2,TXNL4A,GPR37,MITF,ADAM22,NPTX1,RETREG1,ZDHHC14,SLC22A4,RBM34,PHLDB1,ASTN2,PDLIM2,ZKSCAN5,LMF1,ZNF24,UBE3B" Drug 7237_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SRPX,BCAS1,CDC14B,MARCH3,KIF1A,MAGI1,CRLF1,QKI,DCAF8,TOM1,IRAK4,CDKL3,FECH,BAIAP2,SEMA4D,SRCAP,TXNL4A,COPS8,GNG4,GRB10,HNMT,INPP5B,MAP4,LRP12,SAMD9,RIPOR1,NEK11,RPS6KA2,RXRA,FAM192A,ELOVL4,ASTN2,TACC1,VGF,ZBTB14,REEP1,MAP3K12,HPS4" Drug 4016_DN (-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "TRMT9B,PDE8B,MARK4,CACNA1I,MYRF,LDLRAD4,CRLF1,LHX2,COL9A3,AATK,PDE4DIP,DZIP3,PARD6A,AASS,MTSS1L,FGF1,USP19,MSL3,POLL,GRM8,DHX35,ADAM22,MX1,PDE4D,MAPK7,ENOX1,KHDRBS2,KIRREL1,ZNF821,PKNOX2,SMARCD3,KDM4B,IQSEC2,ARC,SYN2,THRA,AMACR,KCNAB1" Drug 4531_DN alpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,APC,RAB28,PLAA,AATK,SNPH,MFAP3L,RUSC2,DMPK,TOM1,ETV1,STON1,CNTRL,SHISAL1,MPP2,MT1M,MX1,CNTLN,RGS4,ZNF821,ZFP30,AMBRA1,DZIP1,FAM214B,LIMCH1,ZNF415,IQSEC2,ZBTB43,IQCE,CRTC1,DNAH7,PARD3,TNS1,TRIO,RPRM,WNT7A,ZBTB14,HPS4" Drug 2039_UP Haloperidol [52-86-8]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,SYT13,APBB2,SCAPER,RAB29,CAST,KRIT1,SOCS5,CTH,RCAN1,RASGRP2,ETV1,ACSL4,SUCO,SEC23B,ATP2C1,OGA,ARFIP1,CRCP,GLYR1,LILRA2,IRAK3,MPP2,ENPP2,ZNF426,TRHDE,LRP12,RETREG2,PPM1B,MAPK10,PCMTD2,AP1AR,KBTBD4,ELMO2,ZC4H2,KLHL7,TCF4,TSN" Drug 5866_DN Estriol [50-27-1]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AMPD2,APOC1,PPFIA3,MARCH3,ZBTB10,SLC4A4,CFLAR,C5,CCNT1,CNOT8,ARMC8,NRG2,CNTNAP2,DBT,PARD6A,TNK2,FHL1,COPS8,GSN,SYNPO,MBD1,MYO9A,ZNF862,NOVA1,CCSER2,SLC25A23,ZSCAN32,AMBRA1,GLT8D1,SPTAN1,STX1A,PDLIM2,PARD3,TRIO,MAP3K12,VPS35L,URM1,ITM2C" Drug CID000000836 "3,4-dihydroxyphenylalanine" Stitch 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "KDM5D,ADCY5,ADCY6,ADCY8,ADORA2A,ATP1A3,SGCE,CBS,SOCS6,CNR1,BOC,TUBD1,TUBB3,PPP1R1B,SCARA3,GAD1,TUBA8,LOXL3,GRIN2C,GRIN2D,IGF1,MAPT,MAT2A,FXYD1,PTN,QDPR,ZFHX4,LRRK2,SNCA,SST,MLST8,TMPO,TUBB2A,TUBB1,UCHL1,DPYSL5,TUBA1A,NELFE" Drug 6693_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APBB2,APOC1,PDE8B,MYRF,ABCG2,RAB26,CSNK1E,VCAN,CNTNAP2,ARHGEF4,ARMCX2,RHOBTB1,TMCC2,STX2,EZH1,TMEM8B,GPER1,GUCY1B1,KCNN1,TM6SF1,NF1,KHDRBS2,GTDC1,KIRREL1,FBXW7,MAPK12,ASAP3,AMBRA1,IQSEC2,DDN,SUPT5H,TMEM121,THRA,CABIN1,TNS1,LMF1,EVI5,KCNAB1" Drug 6433_DN 5707885; Down 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "PKP4,GAS7,ARNTL,BCL7A,GYG2,CFAP410,SEPT7,TAOK2,FAM189A2,VAX2,AKAP7,BAG4,EXOG,DMPK,DNAH9,STX2,FHL1,TRAF3IP2,ERAP1,HTATSF1,FERMT2,GRIK5,RASSF8,ITPKB,KHK,MAP4,MAPT,NF1,PIK3R1,ELOVL2,RGS3,FNDC3A,KDM4B,R3HDM1,PLPPR2,LAT2,HPS4,UBE3B" Drug 2539_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADRA1D,AMPD3,ARRB1,SLC4A4,KIF1A,SLC16A4,SCARB1,KCNAB3,HOMER3,ARHGEF10,SPOCK3,DTNA,FCF1,RASGRP2,MTSS1L,VPS26C,KAT8,PDLIM5,GAA,INPP5K,ADAM28,TJAP1,MAP4,N6AMT1,MYT1,NF1,NNAT,NPR2,PIK3R1,FRMPD1,BTBD7,SNCA,EXOC7,DMXL2,TRIO,FLRT2,PLPPR2,EMSY" Drug 2367_UP Vincamine [1617-90-9]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BIN1,MARK4,AZGP1,BACH1,MTMR3,CAMK2G,SEPT7,FAM149A,CRY2,SIPA1L1,VCAN,PDE4DIP,SLITRK5,DBN1,RCAN1,COQ7,DLC1,FGFR1,GPR12,ELOVL5,GIT1,ZNF862,NF1,PLCB2,TMEM231,SCN2B,KDM4C,PEG10,SEPT8,TACR1,SIN3B,PHF24,TK2,TNS1,TRO,TUBB1,PLPPR2,PCBP4" Drug 2399_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABHD6,AP2A2,PKP4,LGR5,ARHGDIG,ARRB1,ATP6V0A1,BMP7,CALB1,KALRN,HIP1R,CHRNA4,SLC4A8,PPP1R16B,EDN3,EIF4G2,NCALD,PDLIM5,KHDRBS3,INPP5K,DIDO1,GRIK5,CACFD1,ICA1,KIT,PPARA,MAPK7,NKAIN1,RGS3,FAIM2,SP4,TROVE2,SS18,PDLIM2,CRTC1,TRPS1,GDPD5,KCNAB1" Drug 6963_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "CDC42BPA,PKP4,ST3GAL5,FOXN3,CREM,DCAF8,TBC1D5,GIT2,DCTN1,ZBTB24,RCAN1,FGFR1,FAM49B,TXNL4A,MSL3,PRRC2B,HNMT,HSF2,RBPJ,KIF2A,NCAM2,NFYA,SLC25A23,FA2H,ROBO1,CCDC25,TRAPPC13,ZFP30,KIF16B,FUZ,ZSWIM8,ITPRID2,SS18,ARHGEF9,COBL,ZNF189,MAP3K12,ACTR3B" Drug 4396_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,ADRA1B,C1QTNF1,BEGAIN,AMPH,APBA2,SEMA4G,CLDN10,TAOK2,TPP1,CNTNAP2,ARHGAP24,SPOCK3,DMPK,OLFM1,FUT9,GCK,GRIK4,IRF8,KCNN2,LAMA2,OGG1,PTX3,ZMAT4,RGS4,SLC6A8,ARHGEF40,OGDHL,LIMCH1,SNCA,ARHGAP26,SYT5,ZEB1,TNS1,MKRN3,SPHK2,EVI5,ITM2C" Drug 3576_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,KCNAB2,ATP2B2,CFLAR,SYNJ2,GYG2,CA4,HAP1,CBFA2T2,RCBTB2,NECTIN3,SNCAIP,ARHGEF10,DTNA,EDNRB,CNNM1,CHL1,GAD1,TXNL4A,JAK2,KCNH2,SMAD1,ADAM22,NF1,NFYA,NNAT,RETREG1,LRP12,POU6F1,PRODH,ZNF493,SYBU,PREX2,SLC9A5,DOP1A,ARHGAP26,PLCB1,DMXL2" Drug 4143_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AQP6,CFLAR,BAIAP3,CHN2,AKAP7,MYEF2,DMPK,RCAN2,F5,FGF1,FGF14,CAMKK2,OGA,ZNF44,GPR162,GFER,GNAO1,GPER1,IRF8,KCNN1,AFDN,ADAM22,TAGLN3,MX1,RETREG1,NECAB2,GDPD2,PTPRB,SUGCT,CNKSR2,SLC8A1,MAPKBP1,KDM4B,SYN2,ADGRL3,KIAA1107,NT5M,NLRP3" Drug 6661_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SPARCL1,ATP2B2,ATP6V0A1,RGS11,CFLAR,BMPR1B,CACNB4,KALRN,MAML1,BRINP1,C2CD2L,DUSP9,OLFM1,GABRA3,NEU3,GFER,RUNDC3A,CACFD1,GRM2,ICA1,MAP2,NRCAM,RETREG1,ZNF426,ZSCAN32,PTPRO,ZSCAN2,CCDC40,SLC11A1,ATP10B,PHLDB1,PHF24,PCDHA6,FLRT2,LAT2,KCNK12,ZNF24,ZNF74" Drug 5445_DN Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "LTBP4,APBB2,PPFIA3,GYG2,CBFA2T2,ARHGEF6,COL4A5,AKAP12,CRY2,CNTNAP2,CTH,RUSC2,TOM1,CNNM1,EZH1,ZNF589,FGFR1,FHL1,SEMA4D,AHDC1,RAB30,GRIK5,HNMT,NTRK2,MAPK7,EMID1,ASAP3,ZKSCAN3,COA1,ZSWIM8,SPART,PLCB1,KIAA0930,SLC44A1,KCNK12,SPHK2,EPM2A,SENP7" Drug 7398_DN Merbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "PPFIA3,CDK13,AKAP7,ABI3BP,RCHY1,CSNK1E,PDE4DIP,PPP6R2,TBC1D5,SGSM2,DNM1,EGFR,TUBD1,SPEG,TRMO,PDLIM5,FAM49B,FYN,TMEM8B,DISC1,GPD2,DHX35,IL6ST,MAN2A2,MITF,NF1,PDE1C,TCP11L1,RXRA,ELMO2,SMARCA4,TMCC1,ERC1,SS18,EXOC7,SYNE1,TRIO,LMF1" Drug 2542_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "TRMT9B,APC,FAM131A,CDK10,KIF1A,CACNA1I,CAPN3,SLC16A4,SPOCK3,CDON,FEM1B,PLXNC1,MRNIP,RASGRP2,CDKL3,KAT8,SEPT9,ALDH1L1,MSL3,GRM8,SLC2A6,KPNA5,MAPT,MYT1,PLCD1,KHDRBS2,RNASEL,MRAS,SLC11A1,BTBD7,KDM4B,KDM4C,STX1A,EXOC7,TAL1,SYNE1,FLRT2,VIPR2" Drug 5738_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AMH,ARRB1,ADGRB1,HAP1,CREM,ABCG1,DTNA,EDIL3,EGFR,ING4,ELN,APC2,CDKL3,PTK2B,GRM2,SOX21,ELOVL5,ICA1,KCNN2,LMO2,SMAD1,MATN3,AFF1,ADAM22,RAD51D,C1orf54,ZCWPW1,RGS4,STUM,TMCC1,IZUMO4,LHPP,DMXL2,PCDHGA10,PIK3R5,AMACR,NT5M,KCNAB1" Drug 7216_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AK2,SEMA6A,ALCAM,APBB2,APLP1,PPP4R4,RGS9,ST3GAL5,CAMK2B,ARHGEF1,CBFA2T2,STOML1,ARHGEF4,RASSF2,EXOG,RASGRP2,IQCG,OGA,GFER,GLYR1,GPR37,GRM8,GUCY1B1,KIFC3,MITF,AFDN,MPP2,PGAM2,PPP3CC,PRKAR1B,PRODH,RGS12,ASAP3,KDM4C,ZC3H13,TTBK2,ARC,CRTC1" Drug 3113_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,AGT,ARHGDIG,BMP7,CAPN3,HIP1R,RUNX1T1,MFAP3L,CDON,OPTN,PLXNC1,CD320,BAIAP2,SRCAP,GRIK5,GRM8,ATXN2L,MAP4,AFDN,MPP2,MX1,NOVA2,NRCAM,PFKFB4,DCHS2,RASGRF1,GAL3ST4,MAP6D1,SNCA,IZUMO4,HECW1,TSPYL2,SYN2,ADGRL3,CRTC1,KCNE5,TUBB1,SLC30A3" Drug 4803_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BRAP,BCAS1,CFLAR,SCAPER,GYG2,CFAP410,ARHGAP33,SIPA1L1,HDAC4,DTNA,FAM49B,KHDRBS3,ZNF44,SRCAP,MALT1,MSL3,IL6ST,JAK2,MIA2,SETD4,PDCD2,PLEC,PPP2R2B,PTCH1,ZCWPW1,RPS6KA2,SBF1,PEX26,RBM34,CEP68,TTBK2,PDLIM2,KIAA0930,CABIN1,TPM1,KCNK12,ZBTB14,KAT6A" Drug 5617_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABHD6,NME5,SEMA6A,APBB2,SYNJ1,RCBTB2,SLIT2,BAG4,NECTIN3,SH2B1,SIPA1L1,PDE4DIP,ZNF804A,LYPD1,FAM198B,DISC1,ALDH1L1,MALT1,SLC2A6,INPP1,KITLG,ZNF862,NEK1,PCDH9,PLXNB1,LRP12,PRKAR1B,TMEM104,FBXW7,FBXO11,BTBD7,KDM4B,THSD1,IQCE,DMXL2,PARD3,FAM155A,REEP1" Drug 1552_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,AP2A2,BACH1,SYNJ2,CAMK2G,CCNT1,CBFA2T2,PCYT1B,CREM,PPP1R16B,SPOCK2,ANKRD46,ACSL4,ZNF589,TMEM164,SEC23B,AFF2,SMC2,DBF4,PRRC2B,ITGAM,KTN1,MYO9A,PDE1C,CCSER2,PLCD1,PRPH,PTPRN2,RNASE1,SH3BP2,ZSWIM8,GLT8D1,MYCBP2,UNC5B,SPTB,TSPYL2,ACTR3B,DPF3" Drug 6132_DN Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "MTUS1,APBB2,NCOA1,SYNJ1,CAPN3,CAST,TAOK2,CREM,CSNK1E,PRKAG2,SRCAP,ZNF276,MSL3,POLL,IL6ST,MAP4,MID1,GIT1,PIK3R1,NLE1,LRP12,PPARA,ZSCAN32,ZNF493,TRIM68,SEC14L1,FAM214B,SLC11A1,ARFGAP1,KDM4C,SIN3B,TNS2,PARD3,HIRA,FLRT2,VIPR2,ZFP37,NLRP3" Drug 2062_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADGRF5,NRXN3,CLCN3,ARMC8,ABI3BP,CREM,CNTNAP2,C2CD2L,FAM13A,MBNL2,MTSS1L,ANKMY1,FGF1,SESN1,MSL3,GNAL,CNTRL,IFI16,GIT1,FSD1,APTX,PTN,TMEM231,GAL3ST4,KCTD17,SUPT20H,FRMPD1,FAM214B,IFT122,LIMCH1,TROVE2,RGL1,SMG6,KIAA0930,WIPF1,XRCC4,ZNF45,EMSY" Drug 1208_UP "estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SEMA7A,PPFIA3,MADD,MARK4,ATP2A2,NRP2,B4GALT6,SULT4A1,WHRN,CSF1R,PARD6A,SPOCK3,DPH1,B4GALNT1,GPD1,GRIK5,GSTM5,TJAP1,IL6ST,ITGA7,LAMA2,MBD1,NTRK2,MAPK7,WDR25,RGS4,GSTCD,SUPT20H,IZUMO4,SEPT8,ARHGEF9,SYT5,MCF2L,AP4E1,VLDLR,TFIP11,SEMA3B,PHTF2" Drug 7336_UP Letrozole [112809-51-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "CDC42BPA,GAS7,CDK10,ARHGDIG,MARK4,CFLAR,CAMK2B,USP2,ARHGEF1,CBARP,LY86,SIPA1L1,TNK2,EZH1,ZNF589,GAD1,SRCAP,GNG4,ELOVL5,ICA1,TJAP1,SMAD1,MGAT3,ADAM22,NF1,CNOT4,NOVA2,PALM,MAPK7,SNRK,ZSCAN32,RAD51D,ZHX3,ZC3H13,EXOC7,CRTC1,ZNF34,HEY1" Drug 4687_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "RALGAPA1,TRMT9B,AMPD3,APBB2,CDC14B,CFLAR,SYNJ2,SCAPER,CAMK2G,DLGAP1,FAM149A,AKAP12,CTH,DTNA,PIPOX,EZH1,DLC1,OLFM1,GAD1,LYVE1,RUNDC3A,ADAMTS13,GRIK5,MMP16,PDE4B,ZDHHC14,ZFHX4,RPS6KA2,ZNF821,FRMPD1,SMARCD3,LIMCH1,ZC3H13,ARHGAP26,SYN2,CABIN1,REEP1,SEMA3B" Drug 5485_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,LTBP4,APLP1,ATP2B2,N4BP2L1,LDLRAD4,HAP1,CAMK2B,PLEKHB1,NCOR2,STX2,REEP2,TPK1,GNAO1,CNTRL,TJAP1,KCNQ3,SMAD1,AFDN,ZNF862,NPY,P2RY1,ENPP2,PURG,PRKCB,WDR25,RIPOR1,KCNIP1,SH3BP2,LIMS2,PKNOX2,ELMO2,KDM4B,HECW1,RGL1,SYT5,TRO,FTSJ1" Drug 5280_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADORA1,BIN1,GAS7,APOC1,CAMK2G,CABP1,CRMP1,RIMS2,DCAF4,CYBB,RUSC2,DMPK,DTNA,PHF20L1,OLFM1,PDLIM5,OGA,ALDH1L1,GCNT2,RUNDC3A,GRIK5,GRM2,IRAK3,HLF,ICA1,AFF1,AFDN,NF1,DCHS2,KLHL11,RPS20,KANSL3,SNAP25,DMXL2,DOCK9,R3HDM1,CHST5,KCNK12" Drug 3274_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NME5,AMPD3,BIN1,OGT,CDC42BPA,ALDH7A1,CACNA1A,HAP1,CBFA2T2,SOCS6,CNTFR,SPOCK2,RUSC2,DTNA,PLXNC1,NCALD,SPEG,SCML2,FGF12,FUT9,SIGLEC8,ADAM28,GNG4,GRB10,ITPKB,MTRF1L,MAPK7,C1orf54,KANSL3,PHLDB1,STX1A,SZT2,PCDHA5,CDK20,TPM2,VLDLR,GDPD5,ITM2C" Drug 6682_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ALK,AMPD3,APAF1,GAS7,NRP2,MYRF,ARHGAP33,FOXN3,NRXN3,PDE4DIP,SPOCK3,CHRDL1,CELSR3,PLXNC1,MTSS1L,HPCAL4,DCTN2,SYT17,HLF,TJAP1,ITPKA,KIFC3,TM6SF1,GIT1,LYRM9,NF1,NNAT,RPS6KA2,ASAP3,CNKSR2,KANK1,JMJD6,SMG6,KLHL4,SZT2,CDK20,TPM2,REEP1" Drug 1582_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ACTN1,NDRG2,BRAP,LRRFIP1,SH2B1,PPP1R16B,C2CD2L,EXOG,DTNB,ENO2,TRMO,ATP2C1,PRRC2B,LILRB4,DIDO1,CACFD1,ICA1,IDH3B,ITGAM,NEFH,PLCB2,PLCD1,CNNM2,SAMD9,TMEM104,PLPPR3,SAFB,SBF1,SH3BP2,EPN2,ELMO2,ARHGAP26,SPTB,NSFL1C,DMXL2,CBX5,UBTF,ST7" Drug 1210_DN alpha-estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADCY6,BIN1,APBB2,PPFIA3,ARRB2,CNTNAP2,SNPH,ERCC2,EFCAB2,TRAF3IP2,ERAP1,GPR37,GUCY1A1,SYNPO,NDP,NFYA,NPR2,STRN3,MBOAT7,MAPK12,SH3BGR,FUZ,PEX26,EPN2,FAM214B,CCDC88A,KDM4B,SPATA7,SPTAN1,SYT1,KIAA0930,SYNE1,SIK3,NACC2,TK2,SSBP2,TRIM9,RNF146" Drug 4132_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AGT,LTBP4,SYT13,APBB2,NRP2,CBFA2T2,CRY2,AATK,CSF1R,SPOCK2,ARMCX2,SPEG,DCTN2,NSG1,FYB1,GPR75,ATXN2L,BACH2,JAK2,KCNJ5,SMAD1,ADAM22,NCF2,PDE1C,GPR85,CEP41,PRKAR1B,PTCH1,CCDC40,TRIM68,SLC14A1,ZC3H13,SSTR2,PHLDB1,TAL1,KIAA1107,PIK3R5,SLC30A3" Drug 6416_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADORA1,ADRA1D,ADGRF5,TRMT9B,APBB2,GAS7,BCAS1,PLA2G4C,LDB2,SOCS6,SULT4A1,NRG2,AATK,RGS6,CNTNAP2,DTNB,SNX29,ANKMY1,DLC1,PDLIM5,FYB1,LPAR4,C2orf72,KHK,MAP2,MARK1,PCBP3,NTRK2,SMOX,FAT4,PKNOX2,SP4,PEG10,ZEB1,TUBB1,UGT8,NLRP3,SENP7" Drug 4000_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AMPD3,GAS7,LGR5,PDE8B,MARK4,SYNJ2,LHX2,RAB26,HOMER3,COL9A3,AATK,BRINP1,MFAP3L,EDN1,HSD17B14,CGREF1,FYB1,GAD1,GFER,GRM8,SYNPO,ICA1,SHISAL1,MAPT,ADAM22,ZCWPW1,KIRREL1,TRA2B,FRMPD1,AMBRA1,NLGN1,LHPP,IQCE,TK2,AMACR,LMF1,REEP1,KCNAB1" Drug 3966_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADORA1,APOC1,N4BP2L1,BAIAP3,CACNA2D1,CAMK2B,CBLN1,CD86,CRLF1,WHRN,AKAP5,GREB1,RIPOR2,HEPH,FRY,TNK2,EPHB1,IGSF6,SPEG,ETV1,ANKMY1,FGFR1,DENND2A,ALDH1L1,STON1,GPER1,GUCY1A1,ICA1,ADAM22,PALM,PTCH1,ZMAT4,RFX2,STUM,SLC19A3,RUNDC3B,LAT2,ADAMTS9" Drug 4007_DN "Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,ADRA1D,BIN1,APC,CDC14B,PDE8B,ALDH7A1,C5,RAB26,HOMER3,WHRN,NRG2,AATK,CSNK1E,CDON,AASS,MTSS1L,EZH1,CINP,DISC1,SEPT9,LPAR4,GRM8,GIT1,ZNF862,KHDRBS2,RPS6KA2,FRMPD1,ASAP3,TSNAXIP1,SPTAN1,KIAA0930,RIMBP2,OSBP2,LMF1,KCNAB1,KAT6A,TIGD6" Drug 7020_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADCY6,ADRA1D,APBB2,SLC25A14,SOCS6,FAM189A2,HDAC9,SGSM2,DTNA,PHF20L1,EPB41L2,CORO2B,FECH,BAIAP2,PRKAG2,FHL1,GALC,IL6ST,NF1,SLC11A2,SETD4,PLXNB1,PRODH,ELOVL2,RIPOR1,ZDHHC14,RGS12,NEK11,FBXW7,SBF1,PEX26,SPTAN1,THSD1,PIK3R5,FAM155A,VLDLR,KCNK12,AP3B2" Drug 2496_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABHD6,ADORA1,SRPX,ANK2,PKP4,PPFIA3,PDE8B,KIF1A,NRP2,KSR1,THSD7A,RAB26,FAM149A,WHRN,COL9A3,CREM,SNPH,RCAN1,EDNRA,RASGRP2,STX2,DLC1,FER,HPCAL4,SRCAP,RUNDC3A,CACFD1,MYT1,RELN,RASGRF1,HECW1,SPART,CLSTN2,THSD1,WSCD1,RPGRIP1L,ZBTB38,KCNAB1" Drug 6080_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "C1QTNF1,ARHGDIG,ALDH7A1,KALRN,ENTPD2,CDH2,ABI3BP,ARHGEF10,SPOCK2,AASS,ZMYND10,FOLR2,GATM,CNTRL,GUCY1B1,SHISAL1,C2orf72,MGAT3,TAGLN3,MYT1,P2RY1,CDK18,PFKFB2,PGAM2,PILRA,PPP1R1A,TRIM68,ZFHX4,KLHDC8A,LIMCH1,UNC5B,ZBTB43,ZEB1,PCDHGB6,CRTC1,R3HDM1,PLPPR2,XRCC4" Drug 5858_UP Delsoline [509-18-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SYN3,ACHE,NME5,SPARCL1,BIN1,EPB41L5,PPP4R4,SYNJ2,ASIC3,COL9A3,BRINP1,RCAN1,CNNM1,FAM13A,RASGRP2,FAM198B,FGF1,SCARA3,IQCG,TRAF3IP2,ALDH1L1,GNAO1,LILRA2,LPAR4,GPR37,SCIN,MATN3,MEF2C,PPARA,PTPRD,BEND5,FBXW7,TCP11L1,SNCA,TMEM121,ZNF74,SPHK2,DPF3" Drug 5753_DN Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AK2,APBB2,CDC14B,CFLAR,B4GALT6,TPP1,ENTPD4,PDE4DIP,SLITRK5,PPP6R2,RUSC2,CDON,EZH1,SCML2,ANKFY1,ATP2C1,OGA,TMEM8B,RASSF8,DHX35,GIT1,ADAM22,ZNF862,SLC25A23,ZNF426,MAPK7,GRAMD1C,CNNM2,FAM184A,CCDC25,TCP11L1,TRAPPC13,LARP4,CEP68,DIP2A,CRTC1,VGF,XRCC4" Drug 6492_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BRAP,BCAS1,SEMA4G,ATP2A2,SCAPER,QKI,CREM,NCOR1,ABCG1,DZIP3,GIT2,CDON,FEM1B,STX2,ERAP1,STON1,GRIK5,KCNF1,KCNH2,MIA2,ZNF862,SETD4,SMOX,TMEM231,RPS6KA2,KIF16B,PEX26,ELMO2,KDM4C,ERC1,CLASP2,EXOC7,CHST8,CDK20,UBTF,VAV1,MPPE1,ST7" Drug 7316_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADCY6,MTUS1,NME5,SCAPER,HIP1R,ARHGEF1,TBRG4,ARMC8,CPS1,HDAC4,LYPD1,EIF5,FGF13,CGREF1,TRAF3IP2,TMEM8B,SRCAP,PRRC2B,RASSF8,SYNPO,HNMT,SHISAL1,JAK2,MN1,TAGLN3,NF1,SLC11A2,POLG,PTPRE,PTPRN2,SUGCT,SUPT20H,AMBRA1,SMARCC2,PARD3,EMSY,EVI5,AAAS" Drug 3541_UP Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,AGT,C1QTNF3,SYT13,CACNA1I,HAP1,CAMK2B,LDB2,ARHGEF2,ARHGAP33,AKAP7,ENTPD4,RASSF2,C2CD2L,HSD17B14,RASGRP2,MALT1,GLYR1,RASSF8,ICA1,IL6ST,NOVA2,P2RY1,PLCD1,PLTP,FAM184A,RGS12,ZNF821,SYBU,KANSL3,SLC6A8,SMARCD3,TROVE2,TNS2,CRTC1,HIF3A,WIPF1,GDPD5" Drug 2198_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABHD6,BIN1,CDK10,ZSCAN18,ADGRB1,SULT4A1,CNTN1,CREM,ABCG1,SIPA1L1,DZIP3,MBNL2,EPHB1,ERBB2,CDKL3,FER,HPCAL4,FLT1,ANKFY1,POLL,STON1,ICA1,KCNJ5,MEF2C,AFDN,MX1,PDE4A,SLC25A23,POU6F1,CNNM2,RGS12,EMID1,SH3BGR,EPN2,ADGRL3,TCF4,SYNE1,TPM1" Drug 4017_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APOC1,SEMA4G,ALDH7A1,SYNJ2,MYRF,KYAT1,CRLF1,TAOK2,RAB26,PICK1,PDE4DIP,DTNA,EDNRA,EZH1,ST3GAL6,AFF2,DLL3,GAD1,SYT17,GFER,ZNF276,POLL,ADAM22,GPR85,RETREG1,GRAMD1C,DCUN1D2,FRMPD1,TSNAXIP1,CDK19,GPR161,THRA,TK2,CABIN1,RPRM,XRCC4,NT5M,SLC17A7" Drug 3762_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "C1QTNF3,PKP4,AQP6,CACNA1I,CDO1,RAB33A,ERC2,RIPOR2,MRNIP,ELN,APC2,DLC1,FGF1,BAIAP2,FYB1,PTPRT,KCNH2,MGAT3,ADAM22,MSR1,TAGLN3,MYO7A,NTRK3,PDE4A,CEP41,MASP1,PTPRO,NKAIN1,RET,RNASEL,DGLUCY,ZNF821,STUM,ZNF423,ZC3H13,PLCB1,PIK3R5,FLRT2" Drug 1544_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADORA2A,BIN1,MARK4,ATP6V0A1,HAP1,HOMER3,CSF1,VCAN,EIF4G2,AGAP2,TDRKH,GRM2,GSN,ICA1,ITPKB,KIFC3,LMO2,AFDN,PLCD1,PRKAR1B,PTN,PKNOX2,SLC6A8,CXXC4,HECW1,ERC1,PEG10,CDK19,ZBTB43,STX1A,KIAA1107,TCF4,TK2,PLPPR2,WIPF1,ZBTB14,EPM2A,RNF170" Drug 6327_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "MTUS1,CDC42BPA,APBB2,PPFIA3,PPP4R4,MADD,CFLAR,SCARB1,CACNA2D2,WHRN,AATK,ARHGAP24,E2F5,CELSR3,PLXNC1,ETV1,PIPOX,ST3GAL6,SCARA3,AFF2,FYB1,ERAP1,RASSF8,ZNF862,NDP,NF1,MINDY2,MAPK7,GAL3ST4,SEMA6D,ST6GAL1,KIAA1107,TBL1X,KCNK12,SPHK2,REEP1,SEMA3B,KCNAB1" Drug 6130_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SYT13,BIN1,LDLRAD4,RGN,MAGI1,CRLF1,CREM,CRYBB1,ABCG1,SPOCK2,OPTN,TNK2,SRPK3,RASGRP2,DLC1,IQCG,PDLIM5,PCDH17,GSTM5,PADI2,ADAM22,FSD1,PPP2R2B,MAPK10,RELN,VPS13C,GAL3ST4,ZFHX4,GALNT10,FERMT1,SMARCD3,DOP1A,TROVE2,MCF2L,TK2,TRIO,UCHL1,SH3GLB2" Drug 7275_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "PPP4R4,BAIAP3,CHN2,CHRNA4,LHX2,NRXN3,CABP1,BAG4,ARHGAP24,CDON,EDIL3,AASS,MRNIP,REEP2,ZNF44,GPR75,POLL,CNTRL,GUCY1B1,LIG4,MARK3,MBD1,MGAT3,MX1,NF1,NPR2,SLC11A2,ENPP2,PRPH,KHDRBS2,AMBRA1,SLC2A5,FNBP1,SPTAN1,SS18,CEP68,RPGRIP1L,SYNE1" Drug 2289_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASPHD1,ADORA2A,AP2A2,ALCAM,APAF1,APLP1,ADAM23,SYNJ2,MTMR3,CACNA1G,USP2,CLTB,DAPK3,DTNB,ING4,PIPOX,ZNF44,GPER1,GRIK5,IGF1,KCNJ5,MATN3,MID1,NNAT,GPR85,PFKFB2,C19orf57,PRKAR1B,PTPRB,RPS6KA2,ASAP3,BTBD7,LIMCH1,ATP10B,DMXL2,PCDHGA10,CRTC1,DPF3" Drug 4534_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASPHD1,MTUS1,PKP4,APC,MARK4,CBFA2T2,NRXN3,HAPLN1,DCAF8,RCAN1,PLXNC1,MRNIP,ANKMY1,SEMA4D,FYN,TRAF3IP2,SRCAP,TJAP1,INPP5B,MAN2A2,GIT1,MYO6,SLC11A2,PIK3R1,KCTD15,PRKAR1B,RPS6KA2,TRAPPC13,MYH15,DDN,IQCE,TCF4,SZT2,RUNDC3B,OSBP2,EMSY,NT5M,NAV3" Drug 6312_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NME5,CFLAR,ST3GAL5,MTMR3,CFAP410,ARHGEF1,SCARB1,CACNA2D2,NRXN3,SULT4A1,AATK,PDE4DIP,DZIP3,KIAA0753,RUSC2,LYPD1,DUSP9,PLXNC1,COQ7,ZNF589,FLT1,TRMO,GSTM5,KPNA5,LIG4,PALM,LRP12,WDR25,PTH1R,RGS3,GSTCD,STUM,SH3BP2,CCDC88A,SMG6,DNAH7,SH3GLB2,NT5M" Drug 4946_UP Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AP2A2,NME5,ALK,TRMT9B,APC,RIPK1,MTMR3,SGCE,CACNA1I,BAIAP3,CDH2,CLGN,ARHGEF6,CSF1R,TBC1D5,DBT,TMCC2,DNM1,DMPK,EDNRA,EGR3,TNK2,GAD1,BTN2A1,HLF,MGAT3,VPS13C,RGS12,MRAS,CCDC88A,TSNAXIP1,IQSEC2,THRA,RIMBP2,TNS1,FLRT2,LAT2,ZBTB14" Drug 6700_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "C1QTNF3,APAF1,APC,ATP6V0A1,SCAPER,CALB2,KALRN,TAOK2,HAPLN1,VCAN,PHF14,RIPOR2,SPOCK2,MFAP3L,DTNB,EDIL3,EDN1,MBNL2,TNK2,ETV1,ZNF589,FGFR1,CAMKK2,CACFD1,ADAM11,AFDN,P2RX7,ACSS3,RPS20,ANKRD6,OGDHL,ZSWIM8,HECW1,AP4E1,TIMP4,R3HDM1,VLDLR,EVI5" Drug 6836_DN Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ALCAM,CDC42BPA,FAM189A2,AKAP7,CREM,CRY2,PPP6R2,ARHGAP32,DTNA,TNK2,RRAGB,EZH1,BAIAP2,TDRKH,GPR37,ITPKB,MAPT,MEIS1,KITLG,MMP16,LYRM9,NF1,CCSER2,TMEM231,ZDHHC14,MSANTD2,RGS12,RIC8B,SEC14L1,SLC9A5,TTC17,TSPYL2,PCDHA6,TK2,PARD3,TRIO,MPPE1,EPM2A" Drug 1108_DN "leukotoxin B (12,13-EODE); Down 200; 0.2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BRAP,OSBPL1A,EP400,NCOA1,STX16,MTMR2,CCNT1,SYNGR3,RAB28,CLCN3,HOMER3,SMARCAL1,DCAF8,DBT,C2CD2L,DMTF1,ACOT8,EGR3,VPS26C,FGFR1,SARAF,MALT1,FERMT2,GRB10,KIF2A,CCSER2,FSD1,DPF2,ZDHHC4,RGS3,EXD2,MAP6D1,TACC1,PJA1,SSBP2,UBE3A,KLC2,ZNF32" Drug 574_UP tetraethylenepentamine pentahydrochloride; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APAF1,APOC1,BAIAP3,HAP1,ARHGAP33,DLGAP1,RCAN1,EDNRA,EGFR,CALCRL,STX2,PTK2B,NSG1,PCDH17,GNAO1,IRF8,IGF1,IL6R,MARK1,MID1,NPR2,P2RY1,PDE1C,LRRN3,MAPK3,C1orf54,RNASE1,TCP11L1,ATXN2,SH3BP2,PREX2,CLASP2,PHF24,SLC35G2,ZMAT3,ZKSCAN5,CLIP2,SLC17A7" Drug 5242_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "LTBP4,AMT,APC,PPFIA3,CFLAR,CFAP410,SYNGR3,CLGN,PLEKHB1,CSNK1E,PARD6A,EDNRA,HIPK3,SUGP2,EGFR,FGF13,IQCG,PDLIM5,HNMT,ICA1,LMO2,MIA2,ADAM22,PRODH,RGS12,RPS6KA2,ABLIM3,LIMCH1,THSD1,DIP2A,PHLDB1,PCDHA5,ZNF34,TK2,PARD3,PLPPR2,VLDLR,EPM2A" Drug 4691_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BIN1,APC,CDK10,MARK4,SCAPER,MTMR3,C5,KYAT1,SLIT2,CRY2,DZIP3,JAKMIP2,STX2,ANKMY1,ACSL4,ZNF589,FGFR1,FHL1,CAMKK2,GFER,POLL,CNTRL,GRM8,KPNA5,SMIM7,FBXW7,ABLIM3,STX1A,IQCE,TBL1X,CABIN1,HIRA,VIPR2,VLDLR,KCNK12,DNALI1,EVI5,KCNAB1" Drug 4775_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "BEGAIN,CDC42BPA,FAM131A,APOC1,LDLRAD4,CD86,RCBTB2,FOXN3,TPP1,ARHGEF6,ARHGEF10,OSBPL3,HEPH,SLC12A6,FYB1,SIGLEC8,DISC1,SYNPO,IRF8,KHK,TAGLN3,NF1,NOVA2,OPRL1,PDE4B,PTPRD,FAT4,TRIM68,NUDT11,SLC14A1,PLCB1,EXOC7,ZEB1,PCDHA5,CLDND1,SLC30A3,ADAMTS9,ST7" Drug 2506_UP Estropipate [7280-37-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "C3orf14,ADORA1,LGR5,ATP1A3,SGCE,USP2,CNTFR,CABP1,RIMS2,BRINP1,HS3ST2,ELN,COQ7,ERBB4,HPCAL4,SIGLEC8,TOX3,GNAO1,GRIN2C,RASSF8,MMP16,MYO6,NRCAM,PRKAR1B,NUDT11,SCN2B,SEC14L1,ASAP3,CNKSR2,ABLIM3,PEX26,DOK5,ASTN2,KIAA1107,DNAH7,TIAM1,TK2,SENP7" Drug 3013_UP Propantheline bromide [50-34-0]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADCY8,ANK2,PDE8B,CHN2,COL9A3,NCOR2,SIPA1L1,CNNM1,SRPK3,RASGRP2,EPHB1,FAM198B,GABRA3,ADAM28,PCLO,SCIN,PACRG,NTRK3,OXTR,PPARA,RIPOR1,RGS4,ZFHX4,NEK11,KIF16B,LIMS2,FAM214B,SLC11A1,ZSWIM8,PEG10,LHPP,PLCB1,SYT1,TBL1X,TNS1,CDK20,TPM2,SPHK2" Drug 2337_UP Kawain [500-64-1]; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "APC,MARK4,NCOA1,CAMK2B,CAMK2G,ABCG2,ZFYVE16,ZNF337,BRINP1,MFAP3L,RCAN1,HPCAL4,SIGLEC8,ZNF276,PRUNE2,LILRA2,MEF2C,MYO7A,NELL2,NNAT,SLC11A2,CCSER2,PLTP,PMP22,MAPK7,ZSCAN32,RASGRF1,GAL3ST4,FAM102A,FERMT1,PKNOX2,KDM4B,IZUMO4,SYT5,HPS4,PCBP4,ST7,UBE3B" Drug 3430_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADRA1D,EPB41L5,NUMB,EIF4G3,CFLAR,GYG2,PLEKHB1,QKI,HOMER3,GPRASP1,C2CD2L,RRAGB,ANKFY1,SYT17,DIDO1,SLC2A6,DHX35,MAPT,ZNF862,NF1,NPR2,PDE4A,PLEC,SLC25A23,RETREG2,MBOAT7,CNNM2,CEP97,MAPK12,PPP4R3A,EPN2,SIRT2,KDM4B,CEP68,TACC1,DOCK9,SLC44A1,NR2C2" Drug 2028_UP Azathioprine [446-86-6]; Up 200; 14.4uM; HL60; HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ASIC1,SEMA4G,MARK4,AZGP1,CA12,CD86,CHN2,SULT4A1,CNTN1,AATK,DBN1,B3GAT3,C2CD2L,RCAN1,FRY,FLNC,FYB1,SRCAP,CACFD1,FAM107A,NINJ2,NTRK3,OCRL,PDE4B,NLE1,SNRK,RGS12,CCDC25,ZFP30,SLC2A5,ATP10B,ZC4H2,IQCE,FBXW11,CHST5,FIP1L1,SMIM8,ACTR3B" Drug 3224_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABHD6,CDC42BPA,ARRB1,RGS20,CRLF1,TAOK2,HOMER3,FAM169A,DAPK3,TSPAN5,BAIAP2,FHL1,OGA,SEPT9,POLL,GNG4,CACFD1,GRM8,RNFT2,HNMT,INPP5B,ITPKB,KHK,MAP4,TM6SF1,CNOT4,PCDH9,ZNF821,FUZ,TROVE2,THSD1,TNS2,CABIN1,CDK20,ZBTB14,EMSY,HPS4,PCBP4" Drug 7090_UP SC 19220; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ABR,AP2A2,MTUS1,CDC14B,ARNTL,GYG2,CA12,LRRFIP1,PDE4DIP,KIAA0586,FCF1,SUGP2,MRNIP,BAIAP2,GALC,SLC2A6,ATXN2L,IL6ST,KCNH2,MSI1,LYRM9,PALM,PRPH,CNNM2,ZNF821,SLC22A4,KDM4B,ZHX3,KDM4C,SPTAN1,ZBTB43,SPART,POGZ,SS18,NXT2,PARD3,KAT6A,SMIM8" Drug 1972_DN Levodopa [59-92-7]; Down 200; 20.2uM; HL60; HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,SPOP,KCNAB2,CASK,MARK4,PLAA,SMARCAL1,DCAF8,DBT,DCTN1,KIAA0753,FKTN,SEC23B,SEMA4D,USP21,OGA,SPIN1,LILRA2,DIDO1,KTN1,MBNL1,NFE2L2,NFYA,PFKFB3,SMIM7,EXOSC10,RETREG2,PCMTD2,ATXN2,SH3BP2,ZNF430,MAPKBP1,SP2,ZEB1,FRYL,TMPO,WBP2,MFF" Drug 3476_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "SYN3,NME5,AK2,MARK4,RASL11B,ATP2B2,CFLAR,HIP1R,LRRFIP1,SRSF11,FOXN3,NECTIN3,ENTPD4,CSF1R,MAML1,CELSR3,IRAK4,ERCC2,FGFR1,PDLIM5,KHK,KPNA5,MAP4,ZNF862,PRKAR1B,RGS12,TCP11L1,EMID1,FUZ,SMARCD3,KDM4B,ZHX3,SPTAN1,KIAA0930,ZNF34,SLC44A1,REEP1,KAT6A" Drug 2487_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "AP2A2,APOC1,CDK10,SLC4A4,SYNJ2,SGCE,C5,ARHGAP33,EPS15L1,STOML1,CNTN1,CRY2,PIPOX,DLC1,KAT8,FGFR1,IQCG,ALDH1L1,HTATSF1,ATXN2L,MAP4,ZNF862,OXTR,PLCD1,PTCH1,PTN,PTPRN2,ZCWPW1,GALNT10,MRAS,PREX2,PEX26,JMJD6,PDLIM2,THRA,TRPS1,MAP3K12,SENP7" Drug 5545_UP Isoflupredone acetate [338-98-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "CDC42BPA,APBA2,APBB2,SEMA4G,PLA2G4C,ALDH7A1,SYNJ1,MTMR3,CAST,TPP1,CNN3,CNTFR,FAM149A,TBC1D5,KIAA0586,DAPK3,DTNA,NRN1,FGF13,FHL1,RUNDC3A,PCLO,HNMT,JAK2,KCNJ5,LIG4,LRP1B,NFYA,NTRK2,STRN3,FSD1,ELOVL2,SYBU,SLC2A5,CLIP2,XRCC4,ZNF24,HRASLS" Drug 1325_DN Lysergol [602-85-7]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "C1QTNF3,N4BP2L1,RIPK1,ENTPD6,UBE2L6,IQCK,VCAN,DBT,DPH1,RABEPK,VPS26C,F8,FCGRT,ATP2C1,MPP6,OGA,INPP5K,ICA1,TJAP1,LIG4,MAP4,NF1,SETD4,OCRL,PLEC,GTDC1,EXD2,GSTCD,CCDC25,ZBTB43,TROVE2,THSD1,FBXW11,TCF4,METTL3,NPDC1,MPPE1,PHTF2" Drug 6072_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "NDRG2,ADD2,GAS7,GYG2,BAIAP3,HAP1,RUNX1T1,FOXN3,GREB1,RASSF2,ELN,RASGRP2,PTK2B,DLC1,ZNF589,FHL1,GFRA2,RUNDC3A,GSTM5,HAS2,MYO7A,PLCD1,MINDY2,PPP5C,C1orf54,TRIM68,RFX2,CARF,SLA,SLC9A5,UNC5B,PHLDB1,SMG6,TCF4,TK2,PDIA2,CLIP2,KCNK12" Drug 5754_UP Cromolyn disodium salt [15826-37-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "TRMT9B,APC,EPB41L5,MARK4,KIF1A,CAMK2B,USP2,AATK,DBT,EXOG,EDNRA,CELSR3,PLXNC1,ING4,FGF12,FGFR1,GATM,ALDH1L1,PRUNE2,LILRA2,PADI2,ELOVL5,MMP16,PALM,NECAB2,MAPK10,ZCWPW1,RXRA,DZIP1,SLC9A5,MCF2L,SYNE1,CRTC1,ICAM5,R3HDM1,ZNF74,NT5M,SLC17A7" Drug 6777_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-04 1.00E+00 7.56E-03 8.51E-02 38 199 "ADCY6,AMT,SEMA4G,CACNA1I,CA4,SLC16A4,VAX2,CSF1,GREB1,ZNF804A,ING4,MRNIP,GLYR1,PCLO,SPACA9,KITLG,MSI1,NOVA2,NPTX1,OPRL1,CDK18,LRP12,PTN,PTPRO,RGS12,KCNIP1,SNCA,KDM4B,TROVE2,PLCB1,TBCEL,RPGRIP1L,SZT2,GPR161,TPM2,CHST5,FAM155A,CLIP2" Drug ctd:D001640 Bicuculline CTD 9.12E-04 1.00E+00 7.60E-03 8.56E-02 10 29 "MPDZ,NCOR2,GABRB3,GABRG1,GABRG2,GRIA2,GRIN2D,OXTR,MAPK3,ARC" Drug CID005195771 1-phenylpentan-3-amine Stitch 9.12E-04 1.00E+00 7.60E-03 8.56E-02 10 29 "CAST,ENO2,MAP2,MBP,NEFM,NEFH,NPY,PRPH,SYP,UCHL1" Drug 3630_UP 0179445-0000 [211246-22-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.16E-04 1.00E+00 7.63E-03 8.59E-02 35 179 "APOC1,ARHGDIG,FUBP1,SCAPER,CACNA2D1,CAMK2B,CCNT1,AKAP6,CRMP1,VCAN,FEM1B,REEP2,FAM198B,IP6K2,CELF1,SRCAP,SESN1,ATXN2L,NELL2,NFYA,CNOT4,NPY,SMIM7,VPS13C,FBXW7,RPS20,DZIP1,PPP4R3A,ZSWIM8,ZBTB43,DDN,DICER1,ZMAT3,VIPR2,MKRN3" Drug 4452_UP geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.16E-04 1.00E+00 7.63E-03 8.59E-02 35 179 "ADRA1D,CBS,ARHGEF2,ABI3BP,CRY2,PDE4DIP,CTH,ZNF804A,SPOCK3,EDN1,F5,REEP2,ELOVL5,KCNH2,MATN3,MMP16,OXTR,TREM2,PALM,PDE4B,PDE4D,MBOAT7,POU6F1,MARCH1,RGS4,TCP11L1,HSPA4L,FRMPD1,DZIP1,SNAP25,RBM34,PDZD2,NFASC,SYNE1,WIPF1" Drug CID009959010 CID9959010 Stitch 9.24E-04 1.00E+00 7.69E-03 8.67E-02 12 39 "CD38,INPP5K,LSS,PCDHGC3,RYR3,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA2,TRPM2,TST" Drug CID000168297 C13932 Stitch 9.29E-04 1.00E+00 7.73E-03 8.70E-02 39 206 "APAF1,ATP2A2,ATP2B2,CACNA1A,CACNA1B,CACNA2D1,CALM1,KRIT1,RGN,CD38,ENTPD2,DYNC1I1,ELN,ENO2,PTK2B,PPP1R1B,SCARA3,ATP2C1,OGA,NEU3,PPARGC1A,CRCP,TCERG1,PACSIN2,MYLK2,IGF1,KCNK3,KITLG,OGG1,ABCB1,QDPR,FBXW7,RYR3,ATXN7,FOXRED1,TACR1,NEU4,PRTFDC1,JPH3" Drug CID000008974 2-chloroadenosine Stitch 9.32E-04 1.00E+00 7.75E-03 8.73E-02 23 102 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,APC,ALDH7A1,B4GALT6,PLCXD3,SNPH,SLC29A4,DPP6,GPR162,PLCD4,TNFAIP8L3,KLHL23,MAP4,PDCD2,PLCB2,PLCD1,RNH1,SST,PLCB1" Drug CID000002124 aluminum fluoride Stitch 9.33E-04 1.00E+00 7.76E-03 8.74E-02 48 268 "ADCY5,ADCY6,ADCY8,ADRB2,MYH7B,PHF12,NT5C3B,ARHGDIA,ATP2A2,KIF1A,RGS9,ARHGEF25,CCK,COPB2,CNOT8,CLTC,PLCXD3,WDR20,DNM1,DNM1L,PTK2B,FECH,MSTN,GNAL,GNAO1,STON1,PLCD4,HP,KITLG,AFF1,AFDN,OXTR,PDCD2,ABCB1,PLCB2,PLCD1,PRKCB,MASP1,PTK2,RGS3,RGS4,PBRM1,CASC3,ARHGAP26,PLCB1,TBL1X,ACTR6,PLD4" Drug 2540_UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.41E-04 1.00E+00 7.82E-03 8.81E-02 33 166 "ABHD6,BIN1,APAF1,ARRB2,CFLAR,ST3GAL5,LDLRAD4,CFAP410,CD86,CD38,COL9A3,CREM,PDE4DIP,PPP1R16B,RUBCN,DOCK4,GSDME,FAM13A,ING4,BAIAP2,FHL1,PDE4B,PDE4D,RETREG1,PTPRO,CLIP1,SEC14L1,ZNF821,SGK1,SPTAN1,DNMBP,TRPS1,CLDND1" Drug CID005488970 Chrysamine-G Stitch 9.46E-04 1.00E+00 7.87E-03 8.86E-02 19 78 "APAF1,APLP1,CACNA1A,CACNA1B,DYNC1I1,ENO2,PPP1R1B,PPARGC1A,TCERG1,PACSIN2,IGF1,OGG1,ABCB1,QDPR,FBXW7,ATXN7,FOXRED1,PRTFDC1,JPH3" Drug 4578_DN Apigenin [520-36-5]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.47E-04 1.00E+00 7.87E-03 8.87E-02 36 186 "C1QTNF1,ZBTB10,CFLAR,KRIT1,LHX2,RASSF2,GIT2,DBT,RHOBTB1,EXOG,EGFR,ERCC2,ST3GAL6,SYNCRIP,ANKFY1,MALT1,IFI16,FAM69A,SMAD1,MEIS1,MITF,PCDH9,LRP12,ING3,MINDY2,AMBRA1,TTC17,ST5,RGL1,KANK1,TBL1X,TCF4,KIAA0930,CLASP1,HEY1,NDRG4" Drug 6783_DN Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ADCY6,ALCAM,APBB2,ARRB1,SYNJ2,SLIT2,PLAA,CRY2,MFAP3L,DMTF1,DTNA,CNTRL,INPP5B,KHK,MAP4,MAPT,ADAM22,CNOT4,PCDH9,MINDY2,PRPH,CLIP1,ZFP30,AMBRA1,NUBPL,SMARCC2,ARHGAP26,SPART,ELOVL4,PLCB1,ARC,TNS2,CABIN1,HIRA,LMF1,XRCC4,REEP1" Drug 7545_UP semustine; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "BRAP,ADGRB1,MPDZ,TAOK2,CREM,RUBCN,GPRASP1,C2CD2L,STX2,CDKL3,EZH1,BAIAP2,CINP,B4GALNT1,SRCAP,TDRKH,CACFD1,FICD,TJAP1,ITGA7,ITPKA,SLC11A2,PDE4D,SAMD9,GAL3ST4,TRIM68,ZNF671,TRAPPC13,HSPA4L,PEX26,UNC5B,ASTN2,TIAM1,TK2,CDK20,SPHK2,EMSY" Drug 2209_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "C1QTNF1,BIN1,APC,DNAH17,CFLAR,CAMK2B,CD86,RCHY1,SIPA1L1,VCAN,DRP2,EDNRA,HIPK3,AASS,SPEG,AGAP2,OGA,GCNT2,ADAM28,BTN2A1,SMAD1,CNOT4,PIK3R1,PLCD1,MAPK7,SH3GL3,ASAP3,SLC2A5,BTBD7,OGDHL,SPP1,NXT2,ADGRL3,DOCK9,LAT2,XRCC4,NT5M" Drug 2563_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "APBB2,ARRB1,CDK13,SLC4A4,ADAM15,LDLRAD4,PLAA,RCHY1,CREM,DBN1,NR1D2,RCAN1,FCF1,GPHN,CD320,PDLIM5,IL6R,MEF2C,AFF1,PPP5C,DEF8,ZSCAN32,TMEM231,ZDHHC14,EXD2,GALNT10,SH3BP2,DDN,NXT2,DMXL2,NSD1,CDK20,ELP5,TSN,XRCC4,ZNF74,LAMP5" Drug 6646_DN Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "APC,SCAPER,MYRF,WHRN,CREM,VCAN,PDE4DIP,HDAC4,GIT2,RUSC2,PLXNC1,COQ7,EZH1,DENND2A,INPP5K,GRM8,MAN1B1,TJAP1,IL6ST,LSS,NF1,CCSER2,PPP5C,MAPK7,PTPRH,RAD51D,SH3TC2,RPS6KA2,AMBRA1,SLC4A3,EPN2,SPTAN1,SS18,SYT1,TMEM121,TFIP11,NAV3" Drug 6677_DN Ciclopirox ethanolamine [41621-49-2]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ADRB2,APC,MARK4,BCL7A,CDC25B,CHN2,HOMER3,WHRN,NRG2,DZIP3,DCAF4,CHRDL1,PLXNC1,COQ7,ERCC2,HPCAL4,DCTN2,TRAF3IP2,ZNF274,GNAL,SPACA9,HLF,NF1,NOVA2,PLXNB1,CNNM2,PID1,ZFP30,ANKRD6,ATF7IP,IQSEC2,TCF4,SLC44A1,THRA,TNS1,UGT8,NAV3" Drug 5432_DN Fenoterol hydrobromide [1944-12-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ASPHD1,BCL7A,SYNJ2,KYAT1,MAGI1,FAM189A2,HOMER3,ABI3BP,ENTPD4,SOCS5,PPP6R2,DAPK3,MFAP3L,C2CD2L,ACSL4,ZNF589,GPD2,GPER1,HNMT,KHK,KPNA5,MPP2,SEC14L1,ZFP30,SLC6A8,RBM34,SPART,COBL,MCF2L,EXOC7,KIAA0930,RPGRIP1L,PARD3,PLPPR2,SPHK2,REEP1,SEMA3B" Drug 4996_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "SEMA6A,CDC14B,CFAP410,ARHGEF6,CSF1,RUSC2,SLC12A6,RCAN1,EZH1,NRN1,FGFR1,AFF2,PDLIM5,OGA,ALDH1L1,SRCAP,SPACA9,IL6R,KITLG,EMID1,SH3BP2,SLA,MAPKBP1,IZUMO4,PEG10,THSD1,PLCB1,SYN2,PCDHGB6,CRTC1,TMEM121,HIRA,FLRT2,SLC30A3,EMSY,SEMA3B,SLC17A7" Drug 6869_DN STOCK1N-28457; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "NDRG2,BIN1,CDC42BPA,APBA2,GAS7,ADAM15,CFLAR,BAIAP3,CA4,CLGN,RAB33A,RASSF2,TBC1D5,DTNA,DUSP9,LRRC17,ANKMY1,BAIAP2,DISC1,GLYR1,RAB30,ATXN2L,HSF2,TJAP1,LIG4,LSS,MBNL1,MIA2,MSR1,NF1,RETREG1,PLEC,RGS12,ELMO2,CEP68,DNMBP,DMXL2" Drug 5965_UP LY294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ADCY6,TRMT9B,CDC14B,SLC2A11,BAIAP3,RCBTB2,TPP1,SULT4A1,NRG2,CSF1,SUSD5,DTNA,C3orf18,FHL1,ZNF44,GNAO1,STON1,PCLO,SPACA9,IRAK3,MAP2,MEF2C,PDE1C,PDE4B,SERPINI1,MAPK7,DCHS2,SAMD9,ZMAT4,SH3GL3,SNCA,ARHGAP26,THSD1,PCDHGB6,AP4E1,VIPR2,PLSCR4" Drug 4431_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "AMH,APAF1,STX16,KIF1A,PROM1,LDLRAD4,RUNX1T1,CBS,MAGI1,STOML1,NCOR2,CSF1,EGFR,ETV1,RAB30,MSL3,CACFD1,KCNB1,KCNN2,ADAM11,MGAT3,AFF1,NEFM,NNAT,PALM,PNMA3,GAL3ST4,EMID1,SCN8A,LIMS2,PKNOX2,ZHX3,MCF2L,SZT2,PCDHGA10,TPM1,SLC17A7" Drug 5239_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ABHD6,PPFIA3,CDK13,ATP2A2,KIF1A,CRLF1,PPP6R2,MAML1,DBN1,C2CD2L,EGFR,EIF5,ENO2,FGFR1,FGFR3,BAIAP2,GCNT2,SRCAP,GFER,MALT1,GRB10,ATXN2L,IL6R,INPP1,KCNF1,MAPT,MBD1,PDE4A,MAPK7,RIPOR1,SNCA,MTCL1,MCF2L,TMEM121,AP4E1,TRIO,GDPD5" Drug 455_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "NDRG2,AGT,ALCAM,GAS7,PDE8B,CA12,AP4M1,CNTFR,SH2B1,INTS1,EXOG,DRP2,MBNL2,EGR3,PLEKHA1,MRNIP,SCML2,FDFT1,RUNDC3A,HPGDS,ATXN2L,MAN2A2,AFF1,MX1,MYO6,NF1,RGS3,TCP11L1,SEMA6D,ATXN2,AMBRA1,ELMO2,TMCC1,COBL,TAL1,FAM155A,VPS35L" Drug 3098_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ADRA1D,ATP6V0A1,KIF1A,BACH1,SOCS6,RAB28,PLAA,AKAP7,ARHGEF10,GPRASP1,DTNA,HIPK3,MBNL2,FER,IQCG,PDLIM5,CAMKK2,GALC,HTATSF1,PRRC2B,GPD2,KPNA5,AFDN,ZNF862,NFYA,RETREG1,PLEC,PLTP,PRKAB2,DPF2,SEC14L1,FNDC3A,PEX26,CDK19,TMPO,PLPPR2,EMSY" Drug 7097_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "BRAP,CASK,ARNTL,FUBP1,RAB29,CLTB,AKAP12,FAM169A,DOCK4,TBC1D5,DBT,ZBTB24,EGFR,GAD1,GRB10,HSF2,IL6R,FAM69A,KIF2A,PAXBP1,MAP4,NFE2L2,NFYA,NME4,SLC11A2,PDE1C,NLE1,PLEC,POLG,RGS4,USP33,SS18,ERBIN,TCF12,UBE2H,LMF1,KLC2" Drug 7490_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "LTBP4,SYT13,APBB2,APOC1,PRX,ADAM15,CFLAR,MTMR3,ARHGEF2,NRXN3,TPP1,TBC1D5,DAPK3,SPOCK2,HIPK3,FEM1B,ING4,FHL1,GLYR1,STON1,GPER1,PCLO,INPP5B,LSS,KITLG,NF1,PTN,ZFHX4,CARF,FNDC3A,BTBD7,LIMCH1,SNCA,SPART,RGL1,VPS13A,SENP7" Drug 5020_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "APC,MARK4,N4BP2L1,RGS11,GYG2,CA4,CNTN1,ELMO1,EXOG,DMPK,HIPK3,ING4,ERCC2,CDKL3,EZH1,KHDRBS3,ATXN2L,KCNN1,KITLG,ADAM22,MX1,ZNF862,NF1,STRN3,MAPK10,PTN,SH3BP2,FAM214B,SMARCD3,CDK19,TBCEL,SMG6,WSCD1,PCDHA6,SLC44A1,EMSY,SEMA3B" Drug 6421_UP PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ABHD6,ADCY6,ADRA1D,MTUS1,ARRB2,SLC4A4,ST3GAL5,CDH2,HOMER3,CNTNAP2,ARHGEF4,SGSM2,FEM1B,SUGP2,MRNIP,FGFR1,FYN,GLYR1,GLUL,STON1,GIT1,PLCD1,SAMD9,NEK11,MCMBP,ATXN7,KIF16B,PEX26,FAM214B,SLC22A4,IFT122,SYT1,IQCE,TK2,WBP2,MAP3K12,MPPE1" Drug 5273_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "RALGAPA1,NME5,AK2,APBA2,APBB2,GAS7,APOC1,CFLAR,CBFA2T2,ARHGAP33,CSF1R,EXOG,FCF1,EGFR,ING4,EZH1,OGA,ZNF44,INPP5K,KCNH2,KHK,MBD1,ADAM22,LRP12,MBOAT7,PPP2R2B,RGS12,SLC25A36,PREX2,POGZ,TACC1,KIAA0930,RPGRIP1L,AP4E1,ZNF34,KAT6B,CDK20" Drug 6938_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ASPHD1,BIN1,AMT,CDC42BPA,APLP1,STX16,KIF1A,CFLAR,CHGB,TAOK2,ARHGEF4,DBT,OPTN,COQ7,LPAR4,GPER1,DIDO1,ELOVL5,JAK2,NNAT,MAPK7,WDR25,KHDRBS2,RGS12,ROBO1,HSPA4L,SH3BGR,DOP1A,IQSEC2,KIAA0930,PCDHGA10,AP4E1,SLC44A1,TRIO,FAM155A,KCNK12,XRCC4" Drug 7385_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "ADCY6,GAS7,LDLRAD4,WHRN,CPS1,HAPLN1,VCAN,PDE4DIP,ARHGAP32,RUSC2,DUSP9,ETV1,FGFR1,GCNT2,CNTRL,SPACA9,GRM8,ICA1,IL6ST,IL12A,INPP5B,KCNF1,MGAT3,MAPK4,SH3TC2,TRAPPC13,MAPK12,NLGN1,SLC2A5,SMARCD3,MYH15,SNCA,TROVE2,NR2C2,AMACR,ZKSCAN5,FAM13C" Drug 6423_DN C75; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-04 1.00E+00 8.07E-03 9.09E-02 37 193 "RALGAPA1,ALCAM,CDC42BPA,PKP4,APAF1,APLP1,CDK10,PPP4R4,SLIT2,COL4A5,CRMP1,PDE4DIP,TBC1D5,DNAH9,NR1D2,EDNRA,STX2,EZH1,KAT8,TXNL4A,HTATSF1,POLL,ICA1,KCNF1,MMP17,MPP2,ADAM22,PRKAR1B,KCTD17,TCP11L1,PEX26,LIMS2,UHRF1BP1L,CEP68,TRIM2,TRIO,PLPPR2" Drug CID000000730 guanosine 5'-diphosphate disodium salt Stitch 9.76E-04 1.00E+00 8.08E-03 9.10E-02 100 650 "ABR,ADCY5,ADCY6,ADCY8,BRAP,ADRA1B,ADRB2,AP2A1,AP2A2,NME5,ARHGAP20,ARHGDIA,ARRB1,SEC11C,AP1M1,CACNA2D1,KRIT1,CCNH,ARHGEF1,ENTPD6,COPB2,CHN1,CHN2,ARHGAP22,CLTC,NGEF,SULT4A1,AKAP5,ENTPD4,SEC24C,GPSM1,ARHGAP32,ARHGAP24,RHOBTB1,DMD,DNM1,ACOT8,DNM1L,EEF1D,KLHL5,FAM13A,EGFR,RASA4,EIF4G1,EIF5,TUBD1,RASGRP2,ERCC2,PTK2B,TUBB3,SEC24B,AGAP2,RASL10A,FUT9,GCK,TUBA8,RAB40B,GNAL,GNAO1,GNG4,LINGO1,ARHGAP36,KITLG,NF1,NME4,OCRL,GNG2,PKM,GPSM2,SEPT4,POLR2F,PRKCB,PTK2,RASGRF1,RNASE1,RPL15,RPS20,RTN1,MRAS,COPZ1,ARFGAP1,ARHGAP26,SUPT5H,ARHGEF9,PLCB1,MLST8,MCF2L,ALG1,TBL1X,ZEB1,TIAM1,TRIO,TSC1,TSC2,TUBB2A,TUBB1,VAV1,XPO1,TUBA1A,RTN4" Drug CID003021728 CI-930 Stitch 9.77E-04 1.00E+00 8.08E-03 9.11E-02 8 20 "ALDH7A1,KRIT1,CIT,PDE1C,PDE3A,PDE4B,PDE4D,PDE1B" Drug CID000002551 carbachol Stitch 9.78E-04 1.00E+00 8.09E-03 9.11E-02 105 688 "ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,AMH,MYH7B,APOC2,SLC4A4,ATP2A2,ATP2B2,ALDH7A1,BCHE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2B,CCK,KRIT1,LRBA,CACNA2D2,CHRNA4,MYL6B,CNR1,PLCXD3,MYEF2,DMPK,EDN1,EDN3,EDNRA,EDNRB,EGFR,ERBB4,RPS6KC1,PTK2B,ATP2C1,FYN,INPP5K,GCNT2,KCNMB4,GNAL,GNAO1,PLCD4,GRM2,GRM8,GUCY1A1,GUCY1B1,IRAK3,HNMT,MYLK2,KCNJ5,KCNN1,KCNN3,MATK,MYH3,MYO5A,MYO6,NPY,NPR2,P2RY1,PDE3A,PIK3C2A,PIK3R1,PKD1,PLCB2,PLCD1,PRKACB,PRKCB,MAPK3,MAPK4,EPDR1,MAPK7,MAPK9,MAPK10,RGS3,RIC8B,RNH1,RPS6KA2,RYR3,MAPK12,MYO18A,SLA,SNCA,ERC1,PEG10,SST,PLCB1,TACR1,TBL1X,TPCN2,ACTR6,PIK3R5,TRPM2,VIPR2,HPS4,PLD4" Drug CID000004795 AC1L1IZ2 Stitch 9.97E-04 1.00E+00 8.19E-03 9.22E-02 53 304 "SYN3,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,AK2,MYH7B,ARRB1,KIF1A,CALM1,KRIT1,ENTPD2,LRBA,MYL6B,CPS1,DNAH9,EGFR,IRAK4,TUBD1,TUBB3,TUBA8,GSN,DDX19B,MYLK2,ITPKA,KHK,MAT2A,AFDN,MYH3,MYO5A,MYO6,MYO9A,P2RY13,PFKFB4,PRKACB,PKIA,MAPK10,PTK2,GSTCD,RYR3,MAPK12,CASC3,MYO18A,SYP,ACTR6,TSC1,TST,TUBB2A,TUBB1,P2RY12,ANKS1B,TUBA1A" Drug 5774_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADCY6,PPFIA3,MARCH3,CFAP410,CAMK2B,ARHGEF1,LRRFIP1,RAB28,SLC4A8,CSF1,DCAF4,DAPK3,C2CD2L,FEM1B,SUGP2,MRNIP,SPEG,ETV1,GNG4,MAPT,GIT1,NPR2,NLE1,PTPRH,FAT4,FAM184A,BEND5,ZNF821,ST6GAL1,KDM4D,KDM4C,ELOVL4,COBL,ZBTB14,NT5M,PLSCR4,KAT6A,GAN" Drug 1720_DN Gliclazide [21187-98-4]; Down 200; 12.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "N4BP2L1,WASF1,KRIT1,CCNT1,CNOT8,CLCN3,QKI,RCAN1,YAF2,MBNL2,KCTD3,DCTN4,ACSL4,FGFR1,SUCO,SEC23B,SEMA4D,PDLIM5,FAM49B,MAP4K5,MPP2,NF1,NFYA,NTRK2,SETD4,LRP12,PTK2,RPS6KA2,CHD9,HECW1,SPART,CLASP2,NXT2,SIRT1,TMPO,LAT2,EVI5,EPM2A" Drug 5219_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ASIC1,ACTN1,APBB2,APC,PPFIA3,CBFA2T2,ARHGAP33,CLGN,FOXN3,CHRNA4,QKI,CSF1,ARHGEF10,DAPK1,ARMCX2,CDON,EDNRA,FECH,AMOTL2,POLL,GPER1,JAK2,NCF2,NOVA2,MAPK10,SNRK,WDR25,RGS12,KIF13A,PEG10,ZC3H13,IQSEC2,IQCE,CHST5,RUNDC3B,TRPM2,ITM2C,HRASLS" Drug 6294_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADD2,ADGRF5,LGR5,PDE8B,KIF1A,SYNJ2,CBFA2T2,LARGE1,LHX2,CRMP1,FAM131B,CELSR3,PLXNC1,TENM1,ETV1,RRAGB,ZNF589,FGFR1,PDLIM5,TRAF3IP2,POLL,STON1,LPAR4,SCIN,MBP,SCAMP5,NOVA1,PFKFB2,STRN3,CNNM2,EMID1,ZFP30,PKNOX2,MYH15,PHLDB1,TK2,NT5M,KCNAB1" Drug 7401_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "APBB2,FAM131A,CDK10,MYRF,ARHGEF2,B4GALT6,QKI,AKAP7,CSNK1E,GPRASP1,HDAC4,SPATA2,SGSM2,DYNC1I1,CDON,EZH1,BAIAP2,SRCAP,GPER1,MAN1B1,MAPK7,SNRK,PTPN13,SUGCT,AMBRA1,PEX26,FAM214B,KDM4D,LIMCH1,TTBK2,EXOC7,KIAA1107,TRIM2,CBX5,BHLHB9,EVI5,MPPE1,MARCH8" Drug 4824_DN Letrozole [112809-51-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADRA1D,BIN1,APBA2,APC,FAM131A,KIF1A,BAIAP3,WHRN,SGSM2,CDON,SUGP2,ENO2,MTSS1L,ERCC2,FHL1,ERAP1,SEPT9,IL6R,SMAD1,MAP4,SLC11A2,RETREG1,PPARA,PTN,CEP97,KCTD17,EMID1,SEC14L1,SNCA,KIF13A,RBM34,SPTAN1,SZT2,TNS2,SLC44A1,PARD3,EMSY,KCNAB1" Drug 3238_DN Ambroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADORA2A,LTBP4,APBA2,ARHGDIG,KIF1A,SCAPER,BAIAP3,SRSF11,QKI,WHRN,ENTPD4,CRY2,CSF1R,FAM169A,EIF4G2,HSD17B14,VPS26C,PDLIM5,DHX35,KCNQ3,MGAT3,KITLG,MSR1,NEK1,PPP3CC,RELN,C1orf54,RGS12,ROBO1,PKNOX2,SMARCD3,SPART,PIK3R5,CDK20,VGF,TFIP11,KCNAB1,TIGD6" Drug 3465_DN Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "CDC42BPA,APC,FAM131A,PPFIA3,EIF4G3,ST3GAL5,CFAP410,TAOK2,BAG4,CREM,CTH,HIPK3,STX2,FECH,ATP2C1,GLYR1,ATXN2L,HNMT,LIG4,GIT1,ADAM22,KCTD15,PPP5C,TMEM104,ZSCAN32,PEX26,SMARCC2,SPART,TROVE2,THSD1,MTCL1,TIAM1,PLPPR2,LMF1,KLC2,KCNK12,REEP1,SEMA3B" Drug 4364_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,ALK,PPP4R4,ATP2A2,SYNJ1,SGCE,CAMK2B,CAMK2G,CNTFR,CPS1,SH2B1,DAPK3,DBT,DMPK,FCF1,EIF4G2,FGFR1,PRELID3A,TRAF3IP2,INPP5K,SRCAP,GRIK5,KCNN2,MAP4,ZNF862,RETREG1,POLG,GRAMD1C,ZSCAN32,NKAIN1,CCDC40,C1orf54,RASA3,SH3BP2,BTBD7,ZBTB43,ARC,ZFP37" Drug 5969_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "MTUS1,PTCH2,RASL11B,BMP7,RAB28,HOMER3,CRMP1,CNTNAP2,EDIL3,FAM13A,CDKL3,F5,SEMA4D,SIGLEC8,POLL,GNG4,TDRKH,FAM69A,KPNA5,GIT1,PALM,PCDH9,MAPK7,PTN,RAD51D,BEND5,EMID1,FRMPD1,SLC12A4,ZNF334,THSD1,SS18,SYT5,ZFPM2,RIMBP2,TPM2,CA14,TFIP11" Drug 4626_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "TRMT9B,APOC1,PDE8B,ATP2B2,CFAP410,CBFA2T2,B4GALT6,RAB28,ABCG2,RAB26,ARHGEF4,FCF1,MBNL2,VPS26C,ANKFY1,EFCAB2,ZNF44,SIGLEC8,SEPT9,MSL3,CACFD1,SHISAL1,MN1,MX1,SETD4,PTPRB,SH3TC2,ATXN7,ZFP30,SLA,ZNF667,TSNAXIP1,PLCB1,TK2,TNS1,FAM13C,KAT6A,PHTF2" Drug 4379_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ASIC1,DOC2A,AMPD3,CDC42BPA,APBB2,ATP2A2,BMP7,CACNA1I,SCARB1,FOXN3,ARHGEF6,PICK1,AATK,NCALD,PIPOX,PTK2B,DLC1,OLFM1,FGFR3,FHL1,SCARA3,KHDRBS3,DISC1,INPP5K,TJAP1,KCNN2,MSI1,MAPK10,SAMD9,SH3BP2,SMARCD3,SNCA,ARC,WSCD1,GPR161,THRA,PDIA2,PLPPR2" Drug 2141_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "SRPX,CDC42BPA,APAF1,SEMA4G,KIF1A,FUBP1,MYRF,SYNGR3,SULT4A1,SIPA1L1,TNK2,C3orf18,VPS13B,HPCAL4,NBEA,SIGLEC8,GPD2,GSN,ICA1,IL6ST,MSR1,NELL2,NF1,PMP22,GRAMD1C,PTPRN2,RIPOR1,SBF1,CCDC92,ANKRD6,ZHX3,TNS2,FAM155A,UBE3A,LMF1,KLC2,ZFP37,SLC17A7" Drug 4076_DN Propylthiouracil [51-52-5]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "CDC42BPA,APBB2,APC,PDE8B,ALDH7A1,ADAM23,RAB28,RAB26,NCOR2,PDE4DIP,BRINP1,SUGP2,EIF4G2,ZNF549,ETV1,DLC1,ST3GAL6,ZNF44,SEPT9,MAPT,MGAT3,PDE4B,SAMD9,ZSCAN32,DZIP1,PREX2,IQSEC2,ADGRL3,RPGRIP1L,PCDHA5,TIAM1,R3HDM1,TNS1,TRIO,HIRA,OSBP2,TRIM9,TIGD6" Drug 3418_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,C1QTNF3,DOC2A,AMPD3,CDC42BPA,GAS7,CDK10,SEMA4G,ARRB1,CDK13,RASL11B,SCAPER,CFAP410,CALB1,SCARB1,CACNA2D2,SOCS6,TPP1,ENTPD4,DCAF8,DTNA,OPTN,SPEG,ACSL4,KAT8,FGFR1,CAMKK2,GLYR1,KCNJ5,KIFC3,KITLG,CHST8,ZNF34,TK2,METTL3,ZKSCAN5,ITM2C,MPPE1" Drug 5700_UP Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "RALGAPA1,MTMR3,C5,BAIAP3,CALB1,CALB2,CD38,CRLF1,SLIT2,OSBPL3,ARHGEF4,EGFR,EGR3,C3orf18,F5,GAD1,RUNDC3A,ICA1,JAK2,SHC3,MYCN,OGG1,ENPP2,STRN3,PTPRB,PTPRN2,KCTD17,TCP11L1,RASA3,ZC3H13,JMJD6,TRIM2,DICER1,TK2,PIK3R5,CHST5,GDPD5,GJC2" Drug 2575_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,AMH,PKP4,MARK4,CFLAR,CA12,THSD7A,KALRN,CAPN3,CHGB,ABI3BP,NRG2,DBT,SPEG,PTK2B,OLFM1,CAMKK2,GPD2,PRUNE2,TJAP1,ITGAM,LAMA2,NOVA2,PAX6,PDE4A,PDE4D,MINDY2,PPP5C,GDPD2,RGS12,CCDC102B,ZSWIM8,ZC3H13,DNMBP,ICAM5,PARD3,SPHK2,PHTF2" Drug 6676_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADD2,MARK4,ADAM23,MTMR3,MYRF,CHN2,PLAA,CPS1,HAPLN1,AATK,PDE4DIP,EDNRA,CELSR3,DCTN2,SEPT9,ZNF276,GNAL,HLF,HSF2,TJAP1,NOVA2,PPP5C,GRAMD1C,PTPRE,PID1,KIRREL1,ANKRD6,CAMTA2,THSD1,VPS13A,TBCEL,TNS1,ZKSCAN5,ZBTB14,ZNF711,TFIP11,NT5M,FZD3" Drug 6679_DN Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "APAF1,APC,GAS7,NCOA1,SYNGR3,FOXN3,SOCS6,ARMC8,VCAN,HDAC9,FEM1B,CNNM1,MBNL2,PLXNC1,ZNF391,ETV1,IQCG,SEMA4D,FAM49B,MEIS1,NF1,PAX6,LRP12,PRKAR1B,GRAMD1C,ZCWPW1,TRAPPC13,ZNF821,ASAP3,FBXO11,PPP4R3A,KDM4C,LHPP,TCF4,DOCK9,TPM2,VGF,SENP7" Drug 2919_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "SEMA7A,RGS20,ATP2B2,NRP2,LDLRAD4,CFAP410,HIP1R,CHN2,SULT4A1,RAB26,CABP1,FAM169A,SEC14L5,SPOCK3,DTNB,ETV1,F5,PRELID3A,GPR162,PCDH17,MGAT3,NRCAM,CLDN11,PGAM2,POU6F1,LRRN3,NKAIN1,CCDC40,GTDC1,TCP11L1,EMID1,SH3BP2,SLC11A1,PDZRN3,DOK5,CDK19,SYT5,PCBP4" Drug 3019_UP Furazolidone [67-45-8]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "SPARCL1,CDC42BPA,BMP7,MTMR3,LHX2,STOML1,FAM149A,NRG2,NCOR2,CSF1,RGS6,AASS,TNK2,MTSS1L,STX2,AFF2,GAD1,ADAM28,RUNDC3A,GPR75,SOX21,HNMT,SCIN,MAPT,MMP16,NELL2,NTRK3,PLXNB1,POU6F1,RFX2,RGS4,CCDC92,KANSL3,SYT5,GPR161,TIAM1,TK2,ZNF225" Drug 7030_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "SYT13,DNAH17,GYG2,CA4,CACNA2D2,SLIT2,RCHY1,CRY2,APPL1,RIMS2,GIT2,SLC12A6,EDNRA,ZNF589,FGFR1,TRAF3IP2,GPER1,GRB10,ELOVL5,IPO5,LSS,MID1,GIT1,LYRM9,ZNF862,NF1,PLEC,PRKAR1B,WDR25,ZDHHC14,RGS4,ZNF821,RBM34,ZSWIM8,SYP,CABIN1,FAM155A,PLPPR2" Drug 4077_DN Diflorasone Diacetate [33564-31-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADRA1D,MTUS1,TRMT9B,DNAH17,ATP1A3,ALDH7A1,LARGE1,NRXN3,ABCG2,RAB26,CNTFR,AKAP5,CRMP1,PDE4DIP,ARHGEF4,SNPH,MFAP3L,CDON,MTSS1L,ST3GAL6,EFCAB2,ZNF44,GNAL,LPAR4,ICA1,MGAT3,MYT1,NOVA2,PLXNB1,PTPRB,KHDRBS2,RGS4,ZNF821,PPP4R3A,MCF2L,SYNE1,OSBP2,NAV3" Drug 5538_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ABHD6,AP2A2,EP400,SCAPER,VAX2,DCAF8,ZNF337,GIT2,KIAA0753,SUGP2,EIF5,DCTN4,COQ7,USP21,SRCAP,AHDC1,RNFT2,KCNF1,MSI1,ADAM22,OPA1,PRKAR1B,ZCWPW1,RGS3,FBXW7,PREX2,SMARCA4,MAPKBP1,FAM208A,SLC44A1,CABIN1,PIK3R5,VAV1,VGF,XRCC4,ZBTB14,MPPE1,GAN" Drug 5785_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADRA1D,BBOX1,AMH,ATP6V0A1,BMP7,CHN2,LHX2,EPS15L1,HOMER3,CNTN1,AKAP5,CSF1,PLXNC1,TENM1,COQ7,FGF1,OLFM1,PRELID3A,GSTM5,NXPH3,KIT,MAPT,ADAM22,TAGLN3,NCAM2,NTRK3,POLG,DIRAS2,CCDC40,ENOX1,KCTD17,SH3BP2,DZIP1,KIAA1107,BHLHB9,RUNDC3B,MKRN3,SLC17A7" Drug 1238_UP "ICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "BIN1,APC,GAS7,ARNTL,CACNA2D1,SCARB1,ABCG1,CSF1,EXOG,DYNC1I1,DTNA,STX2,BAIAP2,GLI2,MSL3,GRIK5,ITGA7,ZNF862,CNOT4,PTN,RAD51D,RGS4,NUDT11,SUPT20H,PEX26,PPP4R3A,LHPP,SYN2,PDLIM2,SZT2,CRTC1,CABIN1,RUNDC3B,WIPF1,ZNF74,ZNF225,EMSY,AAAS" Drug 2713_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "BEGAIN,BIN1,FGD2,CHRD,ADGRB1,CAMK2B,LARGE1,CHN2,CNR1,PICK1,CNTN1,ABCG1,DAPK1,FGF12,AMOTL2,FOLR2,NSG1,SIGLEC8,GFER,LYVE1,GSN,ICA1,KIT,LAMA2,MAPT,MBP,NTRK2,PDE4D,PGAM2,PLCL1,NECAB2,PTPRH,CCDC40,ANKRD6,TIAM1,RPRM,PRDM10,PLSCR4" Drug 6996_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "CDC42BPA,CDK13,ARHGEF7,C5,PLAA,PPP6R2,ZNF337,B3GAT3,MFAP3L,EXOG,TNK2,VPS26C,SEMA4D,FAM49B,ZNF276,FERMT2,GPR37,MITF,LYRM9,NF1,PCDH9,POLG,PPP5C,TMEM104,ZCWPW1,FNDC3A,ZHX3,SP2,ZBTB43,TSPYL2,ARHGEF9,TBL1X,BHLHB9,HIRA,VGF,URM1,EPM2A,GAN" Drug 3097_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "NDRG2,BRAP,MTUS1,PPFIA4,CDK10,ZBTB10,ADAM15,LDLRAD4,HIP1R,IQCK,CREM,ZNF337,DPH1,DTNA,HIPK3,ENO2,VPS13B,COQ7,PTK2B,FLT1,CAMKK2,SRCAP,IL6ST,AFDN,N6AMT1,MAPK7,BEND5,TCP11L1,HSPA4L,SLC2A5,KDM4B,DOP1A,JMJD6,TRPS1,XRCC4,ZNF24,PRDM10,NLRP3" Drug 5012_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AK2,BIN1,APBA2,FAM131A,ARRB1,ST3GAL5,MAGI1,FOXN3,LHX2,STOML1,AKAP7,RIMS2,SEC14L5,C2CD2L,SGSM2,DNM1,ZNF589,BAIAP2,FHL1,PDLIM5,CGREF1,USP19,RASSF8,IL6R,MSI1,ZNF862,PRPH,WDR25,CEP97,GTDC1,RGS12,CPEB3,BTBD7,LIMCH1,ZHX3,CLSTN2,CRTC1,MPPE1" Drug 4440_UP LY 294002; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADRA1D,ARSE,PDE8B,SLC2A11,N4BP2L1,ST3GAL5,GYG2,CALB2,CAMK2A,HIP1R,RUNX1T1,CDO1,TAOK2,VAX2,CHRDL1,CDON,TENM1,FYB1,GATM,GPR75,GNAO1,KCNF1,KCNH2,LSS,MYO7A,NPTX1,RETREG1,PPP1R1A,PTN,PTPRN2,CARF,LIMS2,PKNOX2,SLC11A1,MCF2L,PCDHGA10,OBSL1,CDK20" Drug 6162_UP Mesalamine [89-57-6]; Up 200; 26.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,ALK,CDC42BPA,APOC1,AZGP1,SYNJ2,CFAP410,RUNX1T1,NDST3,CNTN1,RIMS2,BRINP1,EDIL3,EDNRA,MBNL2,ING4,FOLR2,DENND2A,RUNDC3A,HPGDS,GNAO1,TDRKH,IL12A,MAPT,CNOT4,NRCAM,NTRK2,PGAM2,CCDC40,FUZ,LIMS2,FAIM2,TMCC1,SPTAN1,CLSTN2,SLC35G2,KCNAB1,GAN" Drug 416_DN clozapine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AK2,LTBP4,GAS7,SLC4A4,FUBP1,CA4,RUNX1T1,CPS1,CDC42BPB,CRMP1,DAPK3,E2F5,FAM13A,CALCRL,TRMO,OGA,TMEM8B,BTN2A1,RNFT2,SCIN,NF1,RETREG1,ZSCAN32,GSTCD,TCP11L1,SLA,ELMO2,CDK5RAP2,ZSWIM8,NMNAT2,SPART,VPS13A,TRIM2,VIPR2,ZNF189,ZNF195,EPM2A,AAAS" Drug 3866_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "APLP1,RASL11B,ATP2B2,ADAM23,USP2,CACNA2D2,STOML1,SULT4A1,PICK1,WHRN,CRY2,TMCC2,SPEG,AFF2,GPER1,SPACA9,DHX35,IRF8,KHK,TM6SF1,MEF2C,AFDN,ADAM22,OPRL1,CLDN11,PGAM2,PNMA3,HKDC1,PKNOX2,SPTB,ARC,DOCK9,HEY1,PIK3R5,CHST5,TRIO,SLC30A3,SLC17A7" Drug 3_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "FAM131A,CHRD,NCOA1,SLC4A4,ATP6V0A1,SYNJ1,CACNA1A,CBFA2T2,STOML1,HOMER3,PCYT1B,BRINP1,C2CD2L,KLHL3,TUBD1,F5,BAIAP2,FHL1,FLNC,SRCAP,DIDO1,TJAP1,NF1,NPR2,NTRK3,CCSER2,PLCD1,PPP2R2B,MAPK10,MASP1,PTPRN,SUSD4,RGS3,KBTBD4,KDM4B,LMO3,COBL,CDK20" Drug 4176_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "TRMT9B,APC,CACNA1G,RUNX1T1,USP2,CDH2,CHGB,WHRN,GREB1,SPOCK3,HS3ST2,MTSS1L,ZNF391,F5,AGAP2,FAM49B,OGA,SEPT9,SOX21,KHK,MID1,MMP17,MSR1,TAGLN3,NNAT,PDE4A,ELOVL2,EMID1,FAIM2,IZUMO4,RBM26,TRIM2,PCDHGB6,SYNE1,DNAH7,R3HDM1,SLC17A7,JPH3" Drug 5412_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "NDRG2,AK2,ARRB1,ATP2A2,BAIAP3,CFAP410,TAOK2,CLTB,CSF1,LRIG1,ARHGEF10,DTNA,MTSS1L,ERBB4,FECH,FHL1,PRELID3A,ERAP1,DISC1,SRCAP,GLYR1,CNTRL,GUCY1A1,KCNJ5,MX1,LRP12,EMID1,FBXO11,CNKSR2,SLC6A8,HECW1,ARC,SYT5,KIAA1107,ZEB1,TRPM2,WIPF1,ITM2C" Drug 2477_UP Etifenin [63245-28-3]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADORA1,C1QTNF1,SYT13,CDC14B,ARSE,PDE8B,PTCH2,BMP7,CACNA1I,CFAP410,SLC16A4,LARGE1,CDO1,PICK1,CREM,DCAF4,BRINP1,CHRDL1,CDON,FER,FGFR1,AGAP2,AFF2,GAA,ADAMTS13,KCNQ3,KIT,MAP4,MEF2C,CCSER2,PPP2R2B,LRRN3,RGS12,TCP11L1,PKNOX2,TSPYL2,PHLDB1,TBCEL" Drug 6470_UP Pipemidic acid [51940-44-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ABHD6,ADCY6,BEGAIN,ALDH7A1,SCAPER,CACNA1I,HAP1,CAMK2B,CLGN,QKI,CRYM,AATK,PDE4DIP,EDN3,EDNRB,FYN,SIGLEC8,SRCAP,GFER,GNAL,LPAR4,ATXN2L,HLF,PACRG,MBD1,ADAM22,NF1,LRRN3,NKAIN1,NUDT11,RPS6KA2,EMID1,KIF16B,ASAP3,PPP4R3A,PCDHA6,PCDHA5,LAT2" Drug 3741_UP Karakoline [39089-30-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "FAM135A,BEGAIN,ARSE,ZSCAN18,RASL11B,N4BP2L1,HAP1,TAOK2,SPOCK3,EDN1,MBNL2,DCTN2,GATM,CNTRL,ICA1,C2orf72,TJAP1,KIFC3,MATN3,NTRK2,CLDN11,PRODH,RGS4,RGS12,CARF,CPEB3,KDM4C,ATP10B,LARP4,ARC,ADGRL3,ZEB1,RPGRIP1L,SLC44A1,BHLHB9,TNS1,CDK20,LAT2" Drug 2665_DN "ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "TRMT9B,PPFIA4,NUMB,MPDZ,CACNA1G,CACNA1A,NCOR2,CDON,MBNL2,MTSS1L,ERBB2,PIPOX,ST3GAL6,FHL1,SEPT9,POLL,SPACA9,GRM8,TJAP1,KHK,MAPT,MGAT3,AFDN,MYO6,NNAT,SLC11A2,CEP97,SCN2B,MRAS,CCDC92,ANKRD6,ARFGAP1,DDN,EXOC7,OBSL1,TNS2,LMF1,XRCC4" Drug 7501_UP Suramin sodium salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AMT,CDC42BPA,NCOA1,ARHGEF2,VCAN,HDAC9,DPH1,MBNL2,ING4,COQ7,ETV1,FGF13,FYB1,DENND2A,CNTRL,SLC2A6,HNMT,INPP5B,LIG4,TAGLN3,PPP5C,ELOVL2,RGS4,FUZ,ELMO2,SLC22A4,KDM4B,DDN,SEPT8,VPS13A,IQCE,SLC35G2,GPR161,R3HDM1,HIRA,LMF1,PCBP4,PHTF2" Drug 5862_DN Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "EP400,MARCH3,ZBTB10,NCOA1,CFLAR,C5,HIP1R,RCBTB2,CNOT8,RAB28,SH2B1,APPL1,PPP6R2,TBC1D5,GIT2,DYNC1I1,GPHN,ST3GAL6,FGF13,TRMO,ZNF276,SCAMP5,TAGLN3,KCTD15,NLE1,SNRK,ZDHHC14,CHD9,TMCC1,SPATA7,SS18,NXT2,ELOVL4,EXOC7,IQCE,LMF1,ZFAND5,NAV3" Drug 1387_UP Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "NDRG3,EP400,PKP4,APAF1,ARRB2,MTMR2,ARHGAP33,ENTPD4,ARHGEF10,PPP6R2,TM9SF4,DBT,TNK2,ERCC2,PDLIM5,CAMKK2,PRRC2B,MAN1B1,AGBL5,KIF2A,NEK1,NTRK3,PLCD1,ZNF426,LRP12,NECAB2,POLG,VPS13C,RNASEL,FBXW7,CLIP1,ATXN7,STUM,SIRT2,IQSEC2,TSPYL2,TNS1,CA14" Drug 6283_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADD1,ALK,SEMA7A,MTMR3,CNTFR,PDE4DIP,DUSP9,EDIL3,PLXNC1,STX2,RRAGB,ABCA8,GAD1,INPP5K,USP19,GLI2,RAB30,ATXN2L,IL6ST,KIF5A,ADAM22,NOVA2,NTRK2,POLG,PTCH1,DZIP1,FAM214B,COA1,DDN,THSD1,PHLDB1,VPS13A,TK2,CDK20,HIRA,WNT7A,NDRG4,KCNAB1" Drug 4173_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADD2,BEGAIN,APBA2,GAS7,AQP6,MARK4,N4BP2L1,CACNA1G,LDLRAD4,CALB1,RUNX1T1,CDH2,AKAP7,DBT,PTK2B,FYB1,ALDH1L1,GPER1,GRM8,NXPH3,IGF1,KIF5A,MID1,NTRK3,PAX6,PPP2R2B,LRRN3,PTPRD,RASA3,CNKSR2,SLC11A1,SLC14A1,PCDHGB6,DOCK9,WIPF1,ZNF711,ITM2C,PARP11" Drug 6518_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,N4BP2L1,SYNJ1,CACNA2D1,CALB2,CLGN,PLEKHB1,TAOK2,CNTFR,VCAN,CNTNAP2,GREB1,RASSF2,SPOCK2,GIT2,SIGLEC8,GNAO1,GRM8,INPP5B,MAN2A2,MGAT3,NF1,NECAB2,PRKAR1B,PTX3,CCDC40,FBXW7,KCNIP1,SNCA,ARHGAP26,SMG6,TRIM2,TLR4,AMACR,WNT7A,FTSJ1,ADAMTS9,JPH3" Drug 6502_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "NDRG2,AK2,GAS7,APOC1,ARHGDIG,ADAM23,SYNJ2,HIP1R,QKI,CSF1R,PDE4DIP,ARHGEF4,MFAP3L,SPOCK3,HS3ST2,MBNL2,GCNT2,HAS2,PACRG,MEF2C,AFDN,ADAM22,NF1,PCDH9,STRN3,LRRN3,GRAMD1C,PRPH,PTX3,TRIM68,SBF1,STUM,FRMPD1,PPP4R3A,EXOC7,WSCD1,SLC30A3,PLSCR4" Drug 666_UP butirosin A from Bacillus vitellinus; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "BIN1,CDC42BPA,ARNTL,EIF4G3,BMP7,FUBP1,CCNT1,SCARB1,TMEM184B,CNTN1,PREPL,CRYM,C2CD2L,DRP2,HIPK3,FCGRT,KAT8,PRKAG2,CAMKK2,SESN1,USP19,MSL3,SLC2A6,MAN1B1,KCNN1,OPRL1,ZSCAN32,RGS3,RNASE1,ZNF821,SLC2A5,INTS9,SPTB,ZC4H2,SEPT8,METTL3,ZKSCAN5,ZNF142" Drug 3773_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ASPHD1,NDRG2,ADD1,AP2A2,C1QTNF3,RASL11B,CACNA1G,CAPN3,RUNX1T1,CHGB,CHN2,STOML1,DBT,CDKL3,DLC1,SEMA4D,GNAL,LAMA2,AFDN,MMP16,NNAT,GPR85,MAPK10,KIRREL1,STK32B,CNKSR2,SLC2A5,PPP4R3A,PKNOX2,BTBD7,FAIM2,IZUMO4,ATP10B,PCDHA5,XRCC4,ZFP37,ZNF225,FAM13C" Drug 2787_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "ADORA2A,ALCAM,CDK13,SLC4A4,SYNJ2,SCAPER,BAIAP3,CACNA1A,CBFA2T2,NDST3,HOMER3,NRG2,PDE4DIP,C2CD2L,SPOCK3,KHDRBS3,ADAMTS13,MMP16,NTRK3,CDK18,ZMAT4,RGS3,RGS12,RPS6KA2,ST6GAL1,DZIP1,SLC2A5,FAM214B,ARHGEF40,LIMCH1,KIF13A,ARC,KIAA1107,PCDHGA10,CABIN1,CDK20,TRPM2,MKRN3" Drug 6191_UP troglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.00E-03 1.00E+00 8.19E-03 9.22E-02 38 200 "AP2A2,SEMA6A,BIN1,SLC4A4,CACNA1I,CAMK2B,CH25H,CSNK1E,DAPK3,SPOCK2,TMCC2,MRNIP,C3orf18,F5,KAT8,AGAP2,DOT1L,ALDH1L1,PCDH17,FAM107A,MMP16,PGAM2,PLCD1,EPB41L4B,C19orf57,MINDY2,CEP41,PTPRD,PTPRN2,KCNIP1,CNKSR2,ANKRD6,PKNOX2,LIMCH1,ZC3H13,MCF2L,WSCD1,GJC2" Drug ctd:D001104 Arbutin CTD 1.01E-03 1.00E+00 8.28E-03 9.32E-02 50 283 "KLHL13,PARG,CPNE5,NRP2,BMPR1B,ARHGEF2,KCNAB3,IGDCC3,DDX46,DLX1,DPYSL2,EMX2,VPS13B,NCALD,FGFR3,FAM49B,BRSK1,GALC,C15orf41,HTATSF1,GPD2,BTN2A1,MAP4K5,PACSIN2,HLF,NEGR1,NKD1,IL6ST,GPR155,RASGEF1B,APTX,KCTD17,PCMTD2,ARX,ASAP3,FBXO11,CNKSR2,ERC1,APOM,TAL1,SIN3B,NEU4,TCF12,DNAH7,TSC1,PRR18,OSBP2,ADAMTS9,SOCS4,SPATA13" Drug CID000001209 L-quisqualic acid Stitch 1.02E-03 1.00E+00 8.31E-03 9.36E-02 35 180 "ACHE,ADCY5,ADCY6,ADCY8,DYNLL1,PLCXD3,EIF4G2,TUBD1,TUBB3,FOLH1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,TUBA8,KCNMB4,GRIA2,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,MAP4K5,MAP4,MBP,PLCB2,PLCD1,ENOX1,PLCB1,TUBB2A,TUBB1,TUBA1A" Drug 5584_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-03 1.00E+00 8.31E-03 9.36E-02 35 180 "NDRG2,AMT,APC,AZGP1,ST3GAL5,CA4,CLGN,CHN2,CSF1R,GREB1,GIT2,MBNL2,EGR3,ING4,EPHB1,ACSL4,OLFM1,DISC1,GCNT2,GLYR1,PCLO,ADAM22,MINDY2,MAPK10,GDPD2,ELOVL2,ST6GAL1,SYBU,PKNOX2,KDM4B,TRIM2,RUNDC3B,VLDLR,WIPF1,SLC30A3" Drug CID000001181 UTP-NA Stitch 1.05E-03 1.00E+00 8.56E-03 9.64E-02 69 420 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,NME5,APC,UPRT,ATP2A2,ATP2B2,CALM1,CCNH,CCNT1,P2RX6,ENTPD2,LRBA,CPS1,ENTPD4,PLCXD3,EDN1,EDN3,ERCC2,PTK2B,POLR1B,NELFCD,CAMKK2,ATP2C1,GCK,KCNMB4,LPAR4,PLCD4,GUCY1A1,GUCY1B1,KCNN1,KCNN3,PACRG,HNRNPM,P2RY13,NME4,NPR2,P2RX7,P2RY1,ENPP2,PKM,PLCB2,PLCD1,POLR2F,PPARA,PRKACB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,MAPK12,SPP1,ARHGAP26,SUPT5H,PLCB1,SYT1,TAF6,TAF9,TCEA1,TK2,UBTF,P2RY12,POLR3H,NELFE" Drug 5258_UP Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "AP2A2,APBA2,CDK13,KSR1,CACNA2D1,CLGN,CACNA2D2,B4GALT6,AKAP6,CRMP1,CSF1,CALCRL,NRN1,PTK2B,SCARA3,HPCAL4,ALDH1L1,SRCAP,ADAM28,TJAP1,ITGA7,NF1,PCDH9,PDZRN4,PTPRD,KLHDC8A,SBF1,FAM214B,KANSL3,KDM4B,IZUMO4,HECW1,SYN2,ZEB1,VLDLR,SLC17A7" Drug 3037_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "ABHD6,MTUS1,KIAA1324,APBA2,DDO,DNAH17,ATP1A3,ADGRB3,NRP2,FUBP1,CHN2,CREM,AATK,SIPA1L1,CNTNAP2,USP6NL,DOCK4,CNNM1,STX2,EYA1,REEP2,CORO2B,GABRG2,GALC,KCNMB4,HNMT,MPP2,NOVA2,PDE4B,KLHL11,SLC11A1,TMCC1,TACR1,PCDHGB6,SLC35G2,ADAMTS9" Drug 868_DN 5182598; Down 200; 25uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "MTUS1,MARK4,ZBTB10,CAST,CBFA2T2,PARD6A,PCOLCE2,EXTL2,ARMCX1,DLC1,SEMA4D,FYN,GPR37,MATK,NEK1,SLC11A2,GPSM2,PRKAB2,PKIA,ELOVL2,CEP97,RIC8B,ZC3H14,SGK1,SMARCC2,DOP1A,UHRF1BP1L,ITPRID2,TACC1,FAM208A,TRIM2,TIAM1,BEX4,TPM1,NPL,XRCC4" Drug 5698_UP Perphenazine [58-39-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "NDRG2,FGD2,CDC14B,CFLAR,HAP1,DLGAP1,SPOCK2,SLC12A6,EGFR,RASGRP2,HPCAL4,TPPP3,GAD1,SIGLEC8,TDRKH,SPACA9,ATXN2L,LRP12,PPP2R2B,PTCH1,RASGRF1,RGS12,TCP11L1,SBF1,ZNF821,CPEB3,PKNOX2,BTBD7,ZC3H13,PLCB1,TRIM2,CDK20,VLDLR,KCNAB1,PARP11,EPM2A" Drug 5958_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "C1QTNF1,PPP4R4,MPDZ,SYNJ1,EPS15L1,PLAA,TPP1,CTH,SPOCK3,DPH1,EDN1,HEYL,FGF1,PDLIM5,RUNDC3A,ICA1,IL12A,MARK1,ADAM22,NF1,OXTR,PDE1C,PDE4D,NLE1,POLG,CEP41,GSTCD,ZNF821,HSPA4L,PDZD2,KDM4C,ARHGAP26,ZBTB43,ZEB1,PCDHGB6,MPPE1" Drug 4207_UP Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "ADRA1D,CDC14B,CDK13,SYNGR3,ARHGEF2,MAGI1,TPP1,HOMER3,AKAP5,PDE4DIP,EDIL3,HIPK3,ING4,IGSF6,PDLIM5,CSPG5,DISC1,ADAM28,RAB30,HLF,LYRM9,NF1,NPR2,MTRF1L,PPARA,PPP2R2B,PRPH,RGS4,ZFP2,PKNOX2,SLC11A1,DOK5,SOX15,DICER1,UCHL1,KCNAB1" Drug 1565_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "NDRG3,ADD1,BEGAIN,MAP4K3,APBA2,MARK4,SYNJ1,CLCN3,PREPL,ING4,FAM49B,OGA,BRD8,GLUL,PCLO,DIDO1,IFI16,MKLN1,PIK3C2A,LRP12,CNNM2,SAMD9,TRIM68,RNASEL,HSPA4L,SLA,MAPKBP1,ZSWIM8,CRTC1,KAT6B,TPM1,ZKSCAN5,CLDND1,XPO1,ZNF32,VPS35L" Drug 6975_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "ADRA1D,AMT,BCAS1,SEMA4G,N4BP2L1,CFLAR,MTMR3,SLIT2,QKI,PDE4DIP,TMCC2,MED12,CNNM1,OPTN,EIF4G2,STX2,FHL1,OGA,SRCAP,HNMT,MAPT,GIT1,ADAM22,PRKAR1B,KCTD17,CPEB3,SYBU,ZHX3,VPS13A,TACC1,TRIM2,RPGRIP1L,TK2,CDK20,CHST5,SEMA3B" Drug 4323_DN Dicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "APC,STX16,CFLAR,CRMP1,PDE4DIP,DBT,EDIL3,HIPK3,EGFR,MBNL2,STX2,CGREF1,FERMT2,SPACA9,GSTM5,RASSF8,ATXN2L,AGFG1,TJAP1,IL6ST,MAP4,NFYA,CNOT4,PDE1C,STRN3,PRKAB2,C1orf54,KIRREL1,CCDC88A,PEG10,TBL1X,TMPO,TRIO,ZNF711,EVI5,KAT6A" Drug 6872_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.05E-03 1.00E+00 8.56E-03 9.64E-02 36 187 "NDRG2,APOC1,ADAM15,CA12,EPS15L1,LRIG1,GREB1,TBC1D5,DTNA,E2F5,FCF1,RASGRP1,APH1A,EGR3,BAIAP2,KCNMB4,HSF2,JAK2,KCNF1,LIG4,LSS,CNOT4,PIK3R1,NLE1,PLEC,RET,GSTCD,SGK1,FNDC3A,NXT2,ASTN2,DMXL2,TRIM2,TRIO,HIRA,EMSY" Drug CID000000595 dl-cystine Stitch 1.05E-03 1.00E+00 8.59E-03 9.68E-02 27 128 "AGT,CASK,NFS1,CBS,MAGI1,CDO1,SLIT2,COL4A5,SMARCAL1,RGS6,CTH,BOC,SV2B,DTNB,FLT1,FYN,IGSF5,GDF9,GRIK4,GRIK5,IGSF11,PIK3C2A,PKD1,PTPRO,KIRREL1,RGS7BP,IFT88" Drug ctd:D000535 Aluminum CTD 1.07E-03 1.00E+00 8.70E-03 9.80E-02 254 1869 "KCNH8,ABR,SYN3,ACHE,CLK4,TMEM132B,RNF157,ADD2,BEND6,SLC24A4,USP35,MARCH4,BBOX1,UNC79,ALK,DOC2A,AMPD2,SEMA7A,PI16,MYH7B,APLP1,BCAS1,CPNE5,AQP6,SFMBT2,PPP4R4,CASK,ARHGDIA,ARRB1,ASPA,CCDC74A,GPR146,ZNF599,GYG2,CACNA1G,IL33,CACNB4,CALB2,KALRN,CAMK2A,CH25H,CERS5,CCNT1,P2RX6,CD38,ENTPD6,LONRF2,ARHGAP33,TIGD7,SOCS6,TAOK2,CLTB,NGEF,FBXO7,LY86,CCDC151,HOMER3,CNTN1,COL4A5,BAG4,MROH8,ARHGEF10,SLITRK5,ERC2,USP6NL,HDAC9,MFAP3L,SV2B,CHRDL1,EXOG,MED12,HIPK3,CNNM1,HEYL,MRO,PLXNC1,TENM1,ELN,EMX2,ENO2,EPB41,RASGRP2,ENPP6,RAB9B,IGSF6,MRPL10,RASL12,HSPA12B,F8,ABCA8,ACSL4,SCML2,CORO2B,FKTN,ZNF589,OLFM1,SPSB4,AGAP2,ANKFY1,SYT3,FOLR2,CELF1,ST6GALNAC3,BRSK1,FYB1,GABRG2,GHDC,RUNDC3A,GLYR1,GPD1,PRUNE2,LILRA2,MCHR1,TMEM121B,DIDO1,PLCD4,PLPP7,GRIN2C,BTN2A1,ZBTB49,LINGO1,ADAMTS6,HAS2,PADI2,PACSIN2,NCKAP1L,CELF5,IGF1,SLC35G1,KCNJ16,KCNN1,KIFC3,KIT,LAMA2,SFXN5,LMO2,LSAMP,SMAD9,MAN2A2,MAPT,MEF2C,AFF1,XRRA1,MN1,MOV10,MSR1,HS6ST3,FXYD7,NEFM,NEFH,NEK1,NF1,ALDH1L2,NINJ2,NPY,DNHD1,OPRL1,TREM2,GLIPR1L2,PCSK1,PDCD2,PDE4B,FAM98B,PIK3C2A,PIK3R1,XRN1,PLCD1,PLEC,TRHDE,SCHIP1,MAGEL2,IRX1,PRKCB,MAPK3,PSD,PTH1R,STK32A,PTPRH,PTX3,SH3TC2,RBBP6,DUSP15,MORC4,FIGN,RFX2,KIF7,RNASE1,DCUN1D2,CARF,ROBO2,RORB,CCDC102B,FAM161B,KCNIP1,TRAPPC13,S100B,MRAS,FRMPD1,SLA,DHX30,SLC6A8,SLC6A11,KBTBD4,EPC1,ZFP1,OGDHL,DMRTC1,RCOR3,SNCA,KIF13A,ATP10B,NKAIN2,APOM,NEK4,SEPT8,RGL1,STXBP1,RHBDL3,NUDT10,ANKRD28,ADGRL3,AGTPBP1,PCDHB7,PCDHA7,PCDHA2,FRYL,CDH22,THRA,KAT6B,TPM2,RGMB,TRIO,TRPM2,KCNE5,SGK3,FLRT2,LAT2,WNT7A,USP32P2,ZFP41,ZNF142,ZNF225,SLC30A4,EVI5,SIGLEC10,PLSCR4,HRASLS,ZNF37BP,RNF170,TTC7A,IFT88,NETO1,SOCS4,SPATA13" Drug CID003309928 1-norokadaone Stitch 1.07E-03 1.00E+00 8.70E-03 9.80E-02 6 12 "CAMK2B,DNAH9,KCND2,PPP3CA,PPP3CC,CABIN1" Drug CID000176108 endothall thioanhydride Stitch 1.07E-03 1.00E+00 8.70E-03 9.80E-02 6 12 "EDNRA,INPP5K,PPM1L,PPP3CA,PPP3CC,CABIN1" Drug CID005310936 Cgp 62349 Stitch 1.07E-03 1.00E+00 8.70E-03 9.80E-02 6 12 "CALB1,CALB2,CCK,NPY,PMP22,SST" Drug CID001201426 6-chloropurine Stitch 1.07E-03 1.00E+00 8.70E-03 9.80E-02 6 12 "ADORA2A,BOC,RNASE1,SALL1,TCF12,SYNE1" Drug 4612_DN Capsaicin [404-86-4]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "TRMT9B,ADAM15,CFLAR,SYNJ2,SPAG9,QKI,ARHGAP32,DAPK3,RUSC2,SLC12A6,RGS17,VPS26C,ZNF589,BAIAP2,FHL1,ANKFY1,SIGLEC8,INPP5K,MSL3,DHX35,FAM69A,MBD1,NDP,NFYA,PLCD1,PLEC,LRP12,GTDC1,SH3BGR,AMBRA1,ST5,ARHGEF9,FBXW11,TCF4,TMEM121,EVI5,RNF146" Drug 3968_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,AK2,APBA2,CDC14B,PPP4R4,SCAPER,ARHGEF2,RAB28,CPS1,CNTNAP2,RIMS2,CYBB,TMCC2,CDON,MRNIP,FGFR3,FHL1,FAM49B,GCNT2,GNG4,GPER1,GPR37,GSTM5,INPP5B,SMAD1,MMP16,ADAM22,PDE1C,PDE4A,PFKFB2,SEMA6D,NLGN1,PREX2,FAM214B,ATP10B,UCHL1,EMSY" Drug 1101_UP catechin; Up 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "APBB2,MPDZ,UBE2L6,EPS15L1,CLOCK,DTNA,EIF5,TNK2,PDLIM5,CGREF1,GLUL,AGBL5,ICA1,MBD1,MKLN1,MYO9A,NCAM2,NEK1,NF1,SETD4,PLEC,ING3,PPP5C,PRKACB,PTK2,ZSCAN32,MORC4,PEX26,IFT122,MYCBP2,ERC1,LHPP,JMJD6,FBXW11,SMUG1,LMF1,ZBTB38" Drug 4132_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "AP2A2,NME5,CDC14B,SLC2A11,CFAP410,MAGI1,PLEKHB1,B4GALT6,STOML1,HOMER3,SH2B1,DBN1,C2CD2L,ING4,ENO2,FGF13,GAD1,GRM8,ELOVL5,INPP5B,AFF1,ADAM22,SLC11A2,SERPINI1,MBOAT7,ELOVL2,PTPRO,TCP11L1,TSNAXIP1,IQSEC2,THSD1,ZNF34,SLC44A1,KCNK12,MAP3K12,EMSY,PCBP4" Drug 4401_UP Apigenin [520-36-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,ADORA1,AZGP1,KALRN,RUNX1T1,CBFA2T2,DLGAP1,CBARP,SULT4A1,HDAC9,DAPK1,SPOCK3,EDN1,EGR3,LRRC17,CDKL3,F5,DLC1,OLFM1,DLL3,FYB1,SESN1,ZNF862,NEFM,NPY,NTRK2,ZMAT4,DCUN1D2,EMID1,RPS20,SEMA6D,SLC2A5,KANSL3,TIMP4,WIPF1,XRCC4,KCNAB1" Drug 6673_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASPHD1,FZD9,ADGRF5,CDC14B,SYNJ1,CAPN3,MTMR7,CBFA2T2,SCARB1,PICK1,PDE4DIP,CNTNAP2,EGFR,PLEKHA1,ING4,IGSF6,ST3GAL6,ERGIC3,FERMT2,ADAM11,KITLG,AFDN,ADAM22,PDE4A,PGAM2,PPP2R2B,PRPH,ENOX1,TCP11L1,SH3BP2,ZNF334,ZSWIM8,IZUMO4,HECW1,ZNF24,ZNF225,KCNAB1" Drug 3903_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NME5,BIN1,APBB2,CDK13,SCARB1,B4GALT6,COL4A5,EXOG,EDNRA,HIPK3,PLXNC1,STX2,ERCC2,EZH1,ACSL4,SCML2,ZNF589,SCARA3,SEMA4D,ATP2C1,PRELID3A,OGA,SRCAP,GPER1,MMP17,NF1,NTRK2,RASA3,TSPYL2,EXOC7,SMG6,HEY1,TK2,FAM155A,PLPPR2,XRCC4,EMSY" Drug 4657_DN Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NDRG3,NME5,CDK10,ARRB2,CBFA2T2,SCARB1,B4GALT6,ABCG2,IQCK,SLC4A8,BAG4,NCOR2,KLHL3,EXOG,EDNRA,ETV1,NOP56,SMC2,HAS2,HNMT,INPP5B,LIG4,MEF2C,NDP,SLC25A23,PRKAR1B,TMEM231,SCN8A,ZFP30,SPTAN1,ARHGEF9,FBXW11,HIRA,XRCC4,EVI5,PLSCR4,AAAS" Drug 4715_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADORA2A,STX16,MTMR3,CSF1R,BRINP1,MFAP3L,DTNA,RGS17,HSD17B14,COQ7,ACSL4,ST3GAL6,ERAP1,ZNF276,MSL3,GNG4,GPD2,TJAP1,FAM69A,NF1,PPARA,PPP2R2B,PRPH,WDR25,ZDHHC14,TCP11L1,ZNF821,ANKRD6,SPTAN1,TROVE2,NXT2,ARC,TRIM2,THRA,VGF,VIPR2,LMF1" Drug 4848_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,ADRA1D,SEMA6A,APLP1,FAM131A,ARRB1,MARK4,ATP6V0A1,SCAPER,CRLF1,CACNA2D2,FAM189A2,FAM169A,DAPK3,JAKMIP2,HSD17B14,MTSS1L,ERCC2,FGFR1,TXNL4A,PCLO,DHX35,KCNN2,MIA2,NF1,CNOT4,RETREG1,SAMD9,KCTD17,ASAP3,PREX2,CDK19,TSPYL2,SS18,RGL1,PHLDB1,ZNF34" Drug 4373_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "CDC42BPA,APAF1,KCNAB2,ARSE,CDK13,CAMK2B,HIP1R,NCOR2,SPOCK2,SPOCK3,HS3ST2,ERBB2,ZNF589,ITGA7,ITPKA,KCNJ5,MGAT3,MMP17,TAGLN3,PCBP3,CDK18,CEP41,RELN,KHDRBS2,EMID1,KCNIP1,SNAP25,IZUMO4,ZC3H13,SYP,SYNE1,DNAH7,ICAM5,RIMBP2,HIRA,UGT8,LAT2" Drug 4417_DN Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADORA1,FAM131A,PPP4R4,LDLRAD4,KYAT1,CBFA2T2,WHRN,CPS1,SEC14L5,RASSF2,MAML1,STX2,DENND4A,INPP5K,ALDH1L1,ICA1,KCNN1,MAN2A2,MAP4,TM6SF1,ADAM22,CNOT4,PDE4A,PLCD1,MTRF1L,MAPK7,RGS12,FNDC3A,TSNAXIP1,WSCD1,ZEB1,PCDHGA10,SLC44A1,R3HDM1,HIRA,VIPR2,EMSY" Drug 6157_DN Kaempferol [520-18-3]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "MTUS1,ARRB1,SYNJ1,SGCE,CAPN3,EPS15L1,PLAA,PCOLCE2,FHL1,FYB1,DISC1,ALDH1L1,ADAM28,RAB40B,LILRA2,IRF8,IL6ST,LSS,MAP4,PTCH1,RIPOR1,PID1,RET,SEC14L1,HSPA4L,AMBRA1,BTBD7,CEP68,THRA,NACC2,PARD3,SSBP2,FLRT2,VIPR2,ZBTB38,REEP1,HPS4" Drug 3841_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADRA1D,APC,CDK10,NUMB,ADAM15,ARHGEF7,CBFA2T2,FOXN3,SOCS6,CLCN3,HOMER3,DAPK3,DTNA,HIPK3,MBNL2,EIF4G1,PLEKHA1,PDLIM5,GLYR1,HTATSF1,MAP4K5,KCNF1,LSS,ZNF862,NEK1,RETREG1,PLCD1,SH3BP2,IQSEC2,ST5,PLCB1,EXOC7,TBL1X,CABIN1,FAM155A,REEP1,PHTF2" Drug 4828_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADD2,ADORA1,ADORA2A,NME5,C1QTNF3,SYT13,APC,GAS7,CFLAR,DCAF4,SNPH,DBN1,DTNA,EDNRB,DLC1,BAIAP2,TOX3,PCLO,LSS,MAN2A2,MSI1,CDK18,PLTP,PRKAR1B,C1orf54,RGS12,FBXW7,ASAP3,PKNOX2,DOK5,ATP10B,SYN2,SYT5,EXOC7,PCDHGA10,OBSL1,HEY1" Drug 1856_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,CDK10,ZBTB10,SPAG9,CLCN3,QKI,VCAN,PPP1R16B,PPP6R2,TBC1D5,KIAA0586,HIPK3,VPS13B,GPHN,VPS26C,ZNF589,FYN,SEPT9,ICA1,KIF2A,MIA2,NF1,NFYA,SETD4,ZFYVE21,MAPK12,FERMT1,PPP4R3A,ERC1,SEPT8,TTBK2,PJA1,TCF4,TPM1,XRCC4,EPM2A,ST7" Drug 2100_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "CFLAR,SYNJ1,CPS1,PDE4DIP,CNTNAP2,FCF1,EGFR,ELN,ETV1,POMT1,SIGLEC8,DISC1,GPR37,GRM8,ELOVL5,IRF8,NF1,CNOT4,PCDH9,PDPK1,PRKAR1B,ELOVL2,TMEM231,GAL3ST4,RGS4,ATXN7,PEX26,BTBD7,ZKSCAN3,PHLDB1,RPGRIP1L,SYNE1,TIAM1,CABIN1,HIRA,MAP3K12,VPS35L" Drug 3422_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ALK,APBB2,PPFIA3,CDK13,ATP6V0A1,CFLAR,GREB1,SNPH,DAPK3,RUSC2,DTNA,C3orf18,OGA,GFER,GLYR1,GNG4,LPAR4,KHK,IPO5,MBD1,NELL2,P2RX7,TMEM104,SH3TC2,ZDHHC14,TCP11L1,EMID1,ASAP3,BTBD7,CEP68,PLCB1,CRTC1,UBTF,PLPPR2,VIPR2,VLDLR,KCNAB1" Drug 1610_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ARNTL,EIF4G3,CFLAR,ARHGAP33,FOXN3,PLAA,CLCN3,QKI,SEC31B,CSF1,CTH,DBN1,DBT,C2CD2L,ZNF589,SMC2,PDLIM5,OGA,FYB1,ZNF638,NXPH3,IL6R,MAP4,MPP2,GPSM2,STRN3,POLG,FAM214B,ARHGEF40,ZC3H13,CDK19,TTBK2,PRRC2C,MCF2L,TK2,ZKSCAN5,ST7" Drug 1860_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,APBB2,ENTPD6,QKI,HOMER3,TBC1D5,DBN1,RCAN1,HIPK3,FRY,PTK2B,ZNF589,COPS8,MAN1B1,MAP4,MKLN1,ZNF862,NF1,SETD4,P2RX7,GPR85,POLG,C1orf109,MCMBP,FERMT1,PPP4R3A,COA1,DOP1A,KANK1,VPS13A,TK2,PIK3R5,PLPPR2,ZBTB14,ZNF23,TRIM9,MAP3K12" Drug 7000_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,ADCY6,DOC2A,APBB2,APLP1,ARRB1,MARK4,KYAT1,EPS15L1,TPP1,SGSM2,MED12,CDON,PHF20L1,EGR3,FAM198B,FHL1,INPP5K,GLYR1,HNMT,TJAP1,MAP4,MAPT,MBD1,MMP16,ADAM22,ZSCAN32,PTPRE,GTDC1,ZFHX4,ZNF821,SH3BP2,SYBU,ELOVL4,WSCD1,THRA,REEP1" Drug 5342_UP Carbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,ABHD6,AP2A2,SEMA6A,ALK,APC,EPB41L5,CFLAR,ST3GAL5,CACNA1I,FOXN3,CLCN3,CRY2,PPP6R2,HDAC4,ZNF589,FER,ANKFY1,OGA,SEPT9,GRB10,KCNN1,MAP4,ZNF862,NPR2,KCNIP1,SLC6A8,SLC9A5,BTBD7,ZKSCAN3,ZHX3,UNC5B,PLCB1,MCF2L,PCDHA6,KCNK12,GDPD5" Drug 258_UP LY294002; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NDRG2,LTBP4,BIN1,ARNTL,ATP6V0A1,SYNJ2,MTMR2,CHN2,CLIP3,ABCG1,MBNL2,ING4,F5,ATP2C1,STON1,PADI2,NXPH3,HNMT,KCNJ5,ADAM22,NF1,RETREG1,PPP2R2B,LRRN3,PPP5C,ZSCAN32,CCDC40,FAM184A,GAL3ST4,GSTCD,PPM1E,NMNAT2,FAM208A,PCDHA5,TRIO,WIPF1,MPPE1" Drug 1185_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "BRAP,MTUS1,APC,ADAM23,CAMK2G,TPP1,ARHGAP32,DBN1,SPATA2,C2CD2L,ENO2,COQ7,ZNF589,POMT1,LILRA2,ITGA7,ITPKB,PDE4D,TMEM104,RET,RNASEL,CCDC25,ATXN7,SEC14L1,GALNT10,PPP4R3A,BTBD3,MAPKBP1,SNCA,ZNF302,VPS13A,IQCE,KIAA0930,ZMAT3,CABIN1,MAP3K12,ST7" Drug 5904_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NDRG2,ADD2,ADORA2A,SEMA6A,SEMA7A,APBB2,CACNA1I,CFAP410,P2RX6,CDH2,RAB33A,WHRN,CSF1R,ELMO1,RUSC2,MBNL2,DLC1,ZNF589,TPK1,DLL3,TRAF3IP2,GPER1,IFI16,KCNJ5,KCNN1,MGAT3,ADAM22,PCSK1,LRP12,PPP5C,ZSCAN2,ZNF493,ZMAT4,RPS6KA2,MRAS,SYNE1,LAT2" Drug 2827_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADORA1,SEMA6A,BIN1,SEMA7A,MARK4,SLC4A4,CFLAR,CAMK2B,HIP1R,ARHGEF2,CSF1R,DAPK3,DTNB,CNNM1,TNK2,C3orf18,EZH1,CORO2B,AFF2,SEPT9,ITPKA,KCNQ3,KHK,MEF2C,MYO7A,NNAT,PLCD1,LRP12,MINDY2,RPS6KA2,SH3BP2,CXXC4,WSCD1,DMXL2,CHST8,CABIN1,GDPD5" Drug 2959_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "APC,RASL11B,ATP1A3,FUBP1,LDLRAD4,RUNX1T1,ENTPD6,ARHGAP33,SLIT2,CSNK1E,RCAN1,FAM13A,PLEKHA1,AGAP2,ALDH1L1,ATXN2L,SCIN,AFDN,GIT1,ADAM22,MYH3,NEFM,CCSER2,KCTD15,PLCL1,SBF1,SLC11A1,SNCA,SPTAN1,ZC4H2,EXOC7,PDLIM2,KAT6B,TNS1,UBTF,LMF1,PRDM10" Drug 7481_DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "BRAP,PKP4,APBB2,CFLAR,AKAP7,BAG4,HINFP,DAPK3,GIT2,C2CD2L,MED12,DTNA,APH1A,EZH1,MALT1,GRB10,HNMT,SCAMP5,NEK1,NF1,NFYA,SETD4,ELOVL2,FAM184A,ZCWPW1,SLC6A8,KDM4B,SOX3,CLASP2,PLCB1,TACC1,TBL1X,CHST8,HIRA,ZNF184,EMSY,ST7" Drug 2258_UP Thalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADCY6,ADRA1B,AP2A2,SYT13,AMH,CAMK2B,SULT4A1,WHRN,CPS1,NCOR2,CSF1R,RIMS2,HIPK3,EIF4G2,PIPOX,PRELID3A,OGA,SEPT9,ADAM28,PRUNE2,MAP4,ADAM11,LRP1B,MYCN,PALM,PPP2R2B,PRKAR1B,GDPD2,CNTLN,RASA3,CPEB3,SLC14A1,ZEB1,TNS1,AMACR,ADAMTS9,SLC17A7" Drug 4599_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "KIF1A,CACNA1A,FOXN3,HOMER3,TOM1,DUSP9,FEM1B,CELSR3,IRAK4,ETV1,FGFR1,CINP,PRELID3A,INPP5K,SRCAP,LPAR4,ITPKA,KCNJ5,MAP2,MBD1,NTRK2,CNNM2,SAMD9,PTPRN2,FAM184A,RNASEL,DCUN1D2,TCP11L1,SMG6,TK2,VGF,VIPR2,WIPF1,XRCC4,KCNAB1,TIGD6,SENP7" Drug 2377_UP Indomethacin [53-86-1]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "BIN1,ARRB1,ARRB2,ATP2B2,MYOM1,MYRF,LARGE1,TAOK2,SLIT2,CRMP1,DGKG,SPOCK2,DTNA,MBNL2,EIF4G2,ELN,PIPOX,ICA1,KCNJ5,KIT,MBP,NF1,CNOT4,PDE4A,CNNM2,ACSM5,FAT4,RGS3,HUNK,GALNT10,PPM1E,FAM214B,SLC6A8,SEPT8,TNS1,CHST5,FLRT2" Drug 4838_UP Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NME5,AMPD3,APC,ADAM15,PLEKHB1,QKI,HOMER3,ENTPD4,CRY2,ZNF337,KIAA0586,DCTN1,SLC12A6,SPEG,RRAGB,AGAP2,IQCG,TJAP1,KHK,LSS,NFYA,NPTX1,OCRL,POLR2F,PRKAR1B,MAPK7,TCP11L1,SAFB,ELMO2,SMARCA4,THSD1,CEP68,ARHGEF9,OBSL1,PARD3,SSBP2,UBTF" Drug 5609_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "AMPD3,APBA2,SLC2A11,ADAM23,CAST,RUNX1T1,CNTFR,ARHGAP24,SPOCK3,EPHB1,FYN,GABRG2,POLL,PRUNE2,STON1,SYNPO,HNMT,KIF5A,TAGLN3,NTRK2,PDE1C,PGAM2,PURG,PPP2R2B,PTPRE,TRIM68,ZFP2,KANSL3,ARHGEF40,SNCA,KIF13A,KDM4B,ZEB1,UCHL1,FLRT2,SPHK2,MARCH8" Drug 2477_DN Etifenin [63245-28-3]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "NDRG2,BRAP,AP2A2,GAS7,CDK10,ADAM15,SRSF11,EPS15L1,RAB33A,CSF1,DOCK4,FGFR1,IQCG,CAMKK2,CELF1,POLL,ATXN2L,IFI16,MAP4,NEK1,PLCD1,PTN,ZNF821,MRAS,FAM214B,DOK5,RBM26,TROVE2,SS18,KANK1,KIAA1107,SZT2,ICAM5,KAT6B,XRCC4,ZNF225,UBE3B" Drug 1024_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "OGT,KCNAB2,APBB2,RGS20,CDK13,GYG2,HIP1R,CBFA2T2,TAOK2,RCHY1,JAKMIP2,LYPD1,EGR3,IRAK4,RCAN2,SCML2,CAMKK2,B4GALNT1,SRCAP,TDRKH,KCNH2,LSS,MPP2,MINDY2,MAPK7,GTDC1,CARF,GSTCD,RBM34,KDM4C,THSD1,DMXL2,PCDHGA10,CHST8,AP4E1,ZNF34,PARD3" Drug 6710_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "GAS7,IL33,MTMR7,FAM149A,HAPLN1,CSF1,RGS6,PDE4DIP,PHF14,CTH,RIMS2,PITPNC1,MFAP3L,PLXNC1,FAM198B,AGAP2,GABRA3,ERAP1,GRM8,ICA1,LSS,AFDN,PDE4B,SMOX,PPP1R1A,PPP5C,MARCH1,KLHDC8A,PNMA8A,EMID1,PKNOX2,SLC11A1,ARHGAP26,SMG6,VIPR2,LAT2,GAN" Drug 2086_DN Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ACTN1,OGT,APAF1,APOC1,ARRB2,ST3GAL5,CNOT8,CLCN3,VCAN,PPP6R2,DBT,SPEG,SCARA3,PDLIM5,INPP5K,ZNF276,GPER1,FICD,GUCY1A1,ICA1,MBD1,NFYA,SLC11A2,KCTD15,CNNM2,CCDC25,SH3BGR,ST6GAL1,BTBD7,ZKSCAN3,COA1,LIMCH1,NXT2,METTL3,NDRG4,PLSCR4,SMIM8" Drug 608_UP NU1025; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "LTBP4,BIN1,ARRB2,HIP1R,CCNT1,TAOK2,ARHGEF6,CTH,DBT,KLHL3,DMPK,ING4,SEPT9,NEU3,TXNL4A,LILRA2,GRIK5,ADAMTS6,RASSF8,PADI2,IRF8,C2orf72,KCNJ5,LAMA2,MBP,NOVA2,NPR2,SMIM7,CCDC40,KDM4B,DOK5,SP4,UHRF1BP1L,TNS1,TRIO,MAP3K12,GDPD5" Drug 3100_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADD2,AP2A2,APBB2,CDC14B,MYOM1,NRP2,CACNA1I,THSD7A,CBFA2T2,CREM,CSF1,RIPOR2,DAPK3,C2CD2L,FAM13A,EGFR,FHL1,PRELID3A,CGREF1,HPGDS,ADAMTS13,GRM2,PADI2,SCIN,ITPKA,MAP4,GIT1,MYO7A,TREM2,PIK3R1,SLC9A5,IZUMO4,DDN,ST5,TBCEL,HPS4,SLC17A7" Drug 2632_DN Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "BIN1,EPB41L5,BCAS1,STX16,BCL7A,SOCS6,VAX2,QKI,ARMC8,SIPA1L1,TM9SF4,DAPK3,GIT2,FBXL5,FCF1,AGAP2,FAM49B,CSPG5,POLL,GPER1,HNMT,DHX35,LIG4,MAP4,ELOVL2,CEP97,ZDHHC4,ABLIM3,ZBTB43,TACC1,DNMBP,TK2,CABIN1,XRCC4,NDRG4,MAP3K12,EMSY" Drug 7164_UP Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "APBA2,PLA2G4C,RGS9,BCL7A,SYNJ2,SCAPER,MTMR3,CACNB4,ARHGEF2,PLAA,CLCN3,NCOR2,EGFR,ING4,ANKMY1,DLC1,FECH,BAIAP2,CGREF1,FYB1,SRCAP,BTN2A1,SLC2A6,INPP5B,LIG4,MAP2,ADAM22,ZNF862,RGS12,TCP11L1,SBF1,NLGN1,SNCA,FAIM2,CLSTN2,VIPR2,VLDLR" Drug 1805_UP Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "KCNAB2,GAS7,ARNTL,NCOA1,KIF1A,SYNJ2,MTMR2,C5,CFAP410,ZMYM4,CSF1,GPRASP1,DBT,C2CD2L,RCAN1,HPCAL4,ARFIP1,COPS8,MSL3,POLL,GPD2,IPO5,CNOT4,SAMD9,CCDC25,NEK11,ST6GAL1,SLC4A3,ZHX3,KDM4C,UNC5B,SS18,TRIM2,TIAM1,PIK3R5,HIRA,ZBTB14" Drug 4320_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "BRAP,APBB2,SRSF11,TAOK2,PLAA,CRMP1,CSNK1E,SPOCK2,MSL3,TDRKH,CACFD1,GSTM5,MAP4K5,RASSF8,ELOVL5,AGFG1,IFI16,IL6ST,INPP5B,MAP4,MMP16,MX1,ZNF862,STRN3,MINDY2,KIRREL1,MCMBP,DZIP1,CCDC88A,DOK5,SAMSN1,SMG6,TMPO,VIPR2,WIPF1,SPHK2,KAT6A" Drug 4537_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "DDO,LGR5,CDC14B,ATP2A2,CBFA2T2,SCARB1,LHX2,CRY2,OPTN,FGF1,FLT1,FYB1,CHL1,DISC1,GFER,LPAR4,JAK2,SMAD1,MAN2A2,LYRM9,POLG,PPARA,MAPK10,PRPH,C1orf54,RGS3,MRAS,SLC11A1,SOX15,ZHX3,ARC,PCDHA5,FLRT2,PRDM10,NAV3,EPM2A,SENP7" Drug 3717_DN Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ASIC1,AK2,APBB2,APC,CDC14B,MARK4,CFLAR,ARHGEF1,ARHGAP33,LARGE1,CACNA2D2,RCBTB2,WHRN,ENTPD4,PHF20L1,SUGP2,MRNIP,FAM49B,CGREF1,ZNF276,IL6ST,GIT1,ZNF426,MINDY2,PRKAR1B,CNNM2,SNRK,SH3BP2,SLC9A5,OGDHL,ARHGAP26,POGZ,DIP2A,STX1A,EXOC7,TMEM121,TRIO" Drug 1364_UP Mefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "N4BP2L1,RIPK1,CFLAR,SCAPER,KRIT1,SRSF11,QKI,SH2B1,NCOR1,ZNF337,DPYSL2,EIF5,FDFT1,PDLIM5,ATP2C1,MPP6,HNMT,IFI16,KTN1,MITF,MX1,NFE2L2,ENPP2,RETREG1,PLCD1,PPM1B,CLIP1,SCP2,SGK1,KBTBD4,ELMO2,ZSWIM8,GLT8D1,SPP1,TTBK2,OBSL1,NACC2" Drug 2682_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "MTUS1,ARRB1,CACNA1G,CAMK2A,CDO1,CLGN,HOMER3,CREM,PDE4DIP,CNTNAP2,RIMS2,DCAF4,SNPH,DGKG,DTNA,EDN3,REEP2,BAIAP2,FHL1,ATXN2L,PFKFB2,NLE1,BCAS3,FAT4,GAL3ST4,KCTD17,MAP6D1,RPS20,SALL1,LIMS2,IZUMO4,TMEM121,ZNF34,TIAM1,TRPS1,ZNF225,EVI5" Drug 4263_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "ADCY6,CHN2,TAOK2,ARHGEF4,DCAF4,GPRASP1,DBT,PLPPR4,PARD6A,DPH1,FAM13A,SPEG,ETV1,POLR1B,FYN,PRRC2B,RNFT2,FAM69A,ITPKB,JAK2,LIG4,NDP,PLCD1,STRN3,AP1AR,SH3BP2,SLC4A3,PPP4R3A,DIP2A,PLCB1,ANKRD12,IQCE,TCF4,TRIO,WIPF1,ZNF189,PHTF2" Drug 7537_DN CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "RALGAPA1,NME5,APBB2,APC,EPB41L5,LGR5,RGS20,CDK13,MARK4,SYNJ2,CNOT8,PDE4DIP,GIT2,CDON,YAF2,EGFR,FGF1,FLT1,GLYR1,GPD2,BACH2,MBNL1,TAGLN3,MYO6,NF1,CNTLN,PTX3,TMEM231,SAFB,ZFP30,SLC9A5,ZNF667,THSD1,ASTN2,WNT7A,ZNF74,SEMA3B" Drug 2828_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-03 1.00E+00 8.70E-03 9.80E-02 37 194 "AP2A2,C1QTNF3,BIN1,PPFIA3,MARK4,CACNA1A,HAP1,ARHGEF2,RCBTB2,CSF1R,ARHGEF10,ELN,NCALD,DLC1,FGF12,BAIAP2,MSL3,ELOVL5,INPP5B,KCNQ3,MAN2A2,MAP4,MIA2,ADAM22,MYO7A,ZNF862,SLC11A2,NTRK2,PCDH9,PRKAR1B,PRODH,SH3BP2,EPN2,SOX3,DMXL2,DICER1,UBE3A" Drug CID000324081 4-anilinoquinazoline Stitch 1.09E-03 1.00E+00 8.81E-03 9.92E-02 7 16 "ABCG2,EGFR,ERBB2,ERBB4,FLT1,KIT,RET" Drug CID000037783 PDBu Stitch 1.09E-03 1.00E+00 8.84E-03 9.96E-02 45 249 "ADCY5,ADCY6,ADCY8,ADORA1,ADRA1B,SLC24A4,AGT,APLP1,ARHGDIA,ALDH7A1,CACNA1B,CACNA2D1,CALM1,CAMK2B,DGKI,LRBA,CLCN3,MYL6B,DGKB,DGKG,EDN1,EDN3,EDNRA,RASGRP1,CELSR3,RASGRP2,FGF1,MYLK2,KCNJ5,MBP,KITLG,PKM,FXYD1,MBOAT7,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PSMA6,SST,PLCB1,ANKS1B,MFF,PLD4" Drug CID000001738 homovanillic acid Stitch 1.10E-03 1.00E+00 8.87E-03 9.99E-02 22 97 "ACHE,AMT,ATP1A3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CCK,QKI,ENO2,LOXL3,GRM2,MYCN,NDP,QDPR,CASC3,SST,VPS13A,MLST8,MGRN1,NELFE" Drug CID000104978 fluo-3 Stitch 1.10E-03 1.00E+00 8.89E-03 1.00E-01 26 122 "ADORA1,AGT,PHF12,ATP2A2,ATP2B2,CACNA2D1,CALM1,CAMK2B,KRIT1,EDN1,EDNRA,ATP2C1,KCNMB4,GRIN2C,GRIN2D,CIT,LSAMP,NACA,P2RX7,P2RY1,ABCB1,PRKCB,PTPRD,QDPR,RYR3,TMPO" Drug CID000009433 aminophylline Stitch 1.11E-03 1.00E+00 8.96E-03 1.01E-01 13 45 "RALGAPA1,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ARHGDIG,ALDH7A1,CCK,NR1D2,PDE3A,TMPO,PDIA2" Drug CID000004539 norfloxacin Stitch 1.11E-03 1.00E+00 8.96E-03 1.01E-01 13 45 "SUMF2,PLCXD3,ENO2,STX2,ZMYND10,USP21,PLCD4,PLCB2,PLCD1,STX1A,PLCB1,NPL,ST8SIA2" Drug CID000072032 2-(aminomethyl)pyrrolidine Stitch 1.12E-03 1.00E+00 9.02E-03 1.02E-01 32 161 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,APC,ATP2A2,ATP2B2,CBS,P2RX6,ENTPD2,LRBA,PLCXD3,ATP2C1,GCK,KCNMB4,LPAR4,GPR34,PLCD4,MAP4K5,P2RY13,NPY,P2RX7,P2RY1,PLCB2,PLCD1,PRKACB,MAPK3,MAPK4,MAPK7,PLCB1,P2RY12" Drug 2675_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.12E-03 1.00E+00 9.07E-03 1.02E-01 35 181 "MTUS1,APAF1,APBB2,NRP2,CD86,LARGE1,EPS15L1,VCAN,PDE4DIP,RCAN1,HIPK3,MBNL2,EGR3,FER,PRKAG2,ERAP1,GNAO1,STON1,GSN,IL6ST,TAGLN3,P2RX7,ENPP2,SMOX,LRP12,CNNM2,SGK1,DOP1A,SPP1,PLCB1,ANKRD28,DNMBP,DNAH7,AP4E1,ZNF34" Drug 2785_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-03 1.00E+00 9.07E-03 1.02E-01 35 181 "ASIC1,C1QTNF3,SLC4A4,ST3GAL5,SCAPER,CBFA2T2,TAOK2,DCAF4,DAPK1,GIT2,DMPK,SHANK1,DUSP9,OPTN,MBNL2,FDFT1,ZNF589,GFER,SLC2A6,HMGCR,ICA1,TJAP1,KCNH2,LSS,C1orf54,KCTD17,ZNF821,SLC2A5,HECW1,SPTAN1,CDK19,ARHGEF9,WSCD1,TRIM2,SEMA3B" Drug 2930_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.12E-03 1.00E+00 9.07E-03 1.02E-01 35 181 "MTUS1,DOC2A,AMPD3,BIN1,CDC42BPA,DNAH17,MPDZ,CAMK2B,CD86,CD38,COL9A3,CREM,ABCG1,SIPA1L1,PPP1R16B,DOCK4,CNNM1,SCARA3,KHDRBS3,GRIK5,KIT,MAP4,MAPT,ZNF862,NINJ2,PDE4D,SLC25A23,MAPK7,RXRA,ZNF821,BTBD7,ARHGAP26,LHPP,PLCB1,UGT8" Drug 2857_UP Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.12E-03 1.00E+00 9.07E-03 1.02E-01 35 181 "CFLAR,CALB2,ARHGEF1,CRLF1,FOXN3,SOCS6,AKAP5,CSF1,PDE4DIP,ZNF337,SPOCK2,ING4,RASGRP2,FGFR1,FGFR3,FAM49B,OGA,GAD1,SESN1,GPER1,KCNH2,KHK,ADAM22,CNOT4,SERPINI1,SNRK,KCNIP1,ZFP2,SOX3,UNC5B,DMXL2,ZMAT3,FLRT2,PLPPR2,LAT2" Drug ctd:C025340 manganese chloride CTD 1.13E-03 1.00E+00 9.13E-03 1.03E-01 74 458 "ACHE,APC,ARHGDIA,ARNTL,ATP2B2,MYOM1,BID,CA8,CD86,NOG,AKAP7,NRG2,CLOCK,NCOR2,RGS6,ARHGEF4,HEPH,EGFR,ENO2,PTK2B,FCGR1A,PPP1R1B,OLFM1,FHL1,FLT1,CAMKK2,SDCBP2,GABRG2,GAD1,ERAP1,TNRC6A,GLUL,MCHR1,GPR34,FAM107A,ATOH8,IGF1,IL12A,ITGAM,SFXN5,MAPT,MBP,NEFH,NFE2L2,NFIX,SLC11A2,NTRK2,ABCB1,FA2H,MAPK3,MAPK9,MASP1,RELN,PTX3,RET,NUDT11,GLDN,S100B,SCN7A,SGK1,SIRT2,SLC11A1,SNCA,VPS13A,NUDT10,TACR1,MCF2L,PCDHA6,TEK,UCHL1,VGF,ZFP41,RTN4,AP3B2" Drug 4296_UP Gossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "PKP4,EPB41L5,AQP6,CDK10,CBS,ARHGEF2,LARGE1,STOML1,CTH,NR1D2,DTNA,MBNL2,ELN,FGFR1,ERAP1,FERMT2,PADI2,IL6ST,MAP4,PFKFB3,PFKFB4,LRP12,PRKAB2,VPS13C,ZSCAN32,PTX3,SLC25A36,CPEB3,DZIP1,SPTB,SSTR2,ARC,TCF4,RUNDC3B,MKRN3,EPM2A" Drug 7397_UP Alexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "SYT13,ATP2B2,ADAM23,CAMK2B,CAST,CARS,ARHGEF2,CRLF1,CTH,RUSC2,DRP2,EDN3,RASGRP2,RRAGB,BAIAP2,DOT1L,ALDH1L1,TJAP1,SCIN,MT1M,NF1,PDE4B,PDE4D,PPARA,NLGN1,SNAP25,IZUMO4,SPTAN1,IQSEC2,TLR4,CABIN1,NPL,CHST5,TRIO,REEP1,KCNAB1" Drug 1865_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "ASIC1,AK2,STX16,CFLAR,SYNJ2,LRRFIP1,DBN1,SPATA2,SUGP2,PDLIM5,FAM49B,OGA,DIDO1,ITGA7,JAK2,MKLN1,NF1,SMIM7,ZNF426,POLG,SNRK,BTBD7,ARHGAP26,SPTAN1,POGZ,SS18,CEP68,DIP2A,PJA1,EXOC7,TCF4,DMXL2,TNS1,EMSY,NT5M,IFT88" Drug 4845_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "PKP4,MADD,ADAM15,KRIT1,LRRFIP1,CSNK1E,SOCS5,ARHGAP32,MAMLD1,EIF4G1,POLR1B,PCYOX1,USP21,INPP5B,MBP,SLC11A2,CCSER2,PLEC,CNNM2,ZSCAN32,MORC4,CHD9,PEX26,TMCC1,CDK19,ZBTB43,TROVE2,PRRC2C,TACC1,TBL1X,SATB2,CBX5,KAT6B,TRIO,UBTF,CLDND1" Drug 4581_UP Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "ADRB2,BCAS1,PPP4R4,CAMK2B,ARHGEF2,RAB28,NRXN3,QKI,CREM,VCAN,PHF14,C2CD2L,SEMA3D,ING4,FLT1,ZNF44,ERAP1,SIGLEC8,SRCAP,ICA1,ITGA7,IPO5,MIA2,MMP16,SNRK,PTPRH,RGS12,RASA3,PPP4R3A,SNAP25,TSNAXIP1,TK2,CDK20,ZNF225,NAV3,PHTF2" Drug 2461_DN Iohexol [66108-95-0]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "ABR,AK2,CDK10,CDK13,STX16,CFLAR,BTK,CD86,SCARB1,HOMER3,RUBCN,GIT2,DBT,DTNA,VPS26C,ZNF589,PDLIM5,FAM49B,ALDH1L1,TXNL4A,MSL3,IL6R,MAP4,PLEC,ZNF426,SNRK,SLC25A36,RASA3,SMARCA4,ARHGAP26,RBM26,TROVE2,POGZ,ZC4H2,HIRA,LAT2" Drug 7466_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 9.32E-03 1.05E-01 36 188 "APAF1,ARHGDIG,ARRB1,CDK13,SLC4A4,ATP2B2,MPDZ,ST3GAL5,SCAPER,BAIAP3,CBFA2T2,SCARB1,RCBTB2,QKI,MFAP3L,MBNL2,MRNIP,VPS13B,ACSL4,FGF12,BAIAP2,FHL1,OGA,ZNF44,KCNH2,MAP4,MPP2,PRKAR1B,PTCH1,RIPOR1,GSTCD,ELOVL4,STX1A,COBL,TRIM2,EPM2A" Drug CID000003779 isoproterenol Stitch 1.18E-03 1.00E+00 9.44E-03 1.06E-01 102 669 "ASIC1,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,BBOX1,AMPD2,AMPD3,ANK2,MYH7B,ARRB1,PDE8B,ATP2A2,ALDH7A1,HCN2,CACNA1A,CACNA1B,CACNA2D1,CALM1,CAMK2B,CCK,P2RX6,CBFA2T2,CD38,LRBA,ASIC3,CHRNA4,CLCN3,MYL6B,AKAP6,MYRIP,CREM,VCAN,DMD,EDN1,EDN3,EDNRA,TUBD1,PTK2B,TUBB3,PPP1R1B,TUBA8,CRCP,GNAL,GNAO1,LPAR4,GUCY1B1,TNFAIP8L3,ITGAM,KCNH2,AFDN,MXI1,MYH3,MYO5A,MYO6,MYO9A,P2RY13,NPY,NPR2,P2RX7,P2RY1,PDCD2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PIK3C2A,PIK3R1,PLIN1,PPARA,PPP1R1A,PRKACB,PRKCB,MAPK3,MAPK7,KLK6,QDPR,RIC8B,RNH1,GLDN,RYR3,S100B,MAPK12,SCN7A,MYO18A,SPP1,SST,HIF3A,ACTR6,TUBB2A,TUBB1,VIPR2,P2RY12,TUBA1A,PLD4" Drug 2875_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ASIC1,CDC42BPA,CDK13,ATP2B2,CACNA1G,ARHGAP33,CLGN,TAOK2,LRIG1,CNTNAP2,RASSF2,SPOCK2,SGSM2,FAM13A,EGFR,C3orf18,SEMA4D,SRCAP,ZNF276,GPER1,MSI1,MX1,CNOT4,PFKFB2,PRODH,KCTD17,PKNOX2,TSNAXIP1,SPTB,IQSEC2,CDK19,RGL1,ARC,SMG6,TRO,PDIA2,XRCC4" Drug 4706_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BIN1,AMT,MARK4,ALDH7A1,WHRN,LRIG1,DBN1,IRAK4,ERCC2,SCML2,ST3GAL6,FGFR1,FYB1,GFER,CNTRL,GRM8,MAP4,MGAT3,ADAM22,ZNF862,NF1,RETREG1,PPARA,PPP2R2B,GRAMD1C,SAMD9,RNASEL,FBXW7,SUPT20H,FAM214B,KIF13A,ZHX3,IQCE,TK2,XRCC4,MAP3K12,KCNAB1" Drug 2702_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "SYT13,AMPH,AZGP1,RGS11,CACNB4,CAMK2A,TAOK2,AKAP6,COL9A3,CREM,SIPA1L1,PDE4DIP,USP6NL,DGKG,HIPK3,AASS,TNK2,FAM198B,PDLIM5,STON1,HNMT,IL12A,MYO7A,MYT1,NTRK3,POLG,SUGCT,ZNF821,ABLIM3,EPN2,SLC11A1,ATP10B,ARC,TACR1,TRIM2,PHTF2,JPH3" Drug 7239_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ALCAM,PPFIA3,CDC14B,CFLAR,SCARB1,VAX2,ARHGEF6,ABCG1,LRIG1,DBN1,MFAP3L,TOM1,FEM1B,PHF20L1,FGFR1,FAM49B,ATXN2L,DHX35,IL6ST,INPP5B,IPO5,MAP4,MAPT,LRP12,TMEM104,PTPN13,CEP97,SBF1,ABLIM3,BTBD7,SOX3,ZSWIM8,KDM4C,ITPRID2,MCF2L,EXOC7,WSCD1" Drug 4211_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ADRB2,CDC14B,BACH1,NRP2,CALB2,SCARB1,SULT4A1,PDE4DIP,DAPK3,SPOCK2,SEMA3D,AGAP2,PDLIM5,PRELID3A,DENND2A,GALC,GPR75,AP4S1,ICA1,MYH3,NF1,OPRL1,SERPINI1,CNNM2,ZSCAN32,SH3TC2,EMID1,ST8SIA1,SLA,SLC11A1,SNCA,TROVE2,TBCEL,PCDHA5,ZKSCAN5,VSNL1,LAT2" Drug 5330_DN Rolipram [61413-54-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BCL7A,CFLAR,CBFA2T2,SOCS6,RAB28,HOMER3,ABCG1,CSNK1E,PPP6R2,DAPK3,DBT,C2CD2L,LYPD1,RCAN1,MUM1,MAP4,NFYA,SETD4,OCRL,PLXNB1,STRN3,MBOAT7,PPP5C,RNASEL,AMBRA1,ABLIM3,KBTBD4,KDM4C,SS18,KLHL7,SUPT5H,TACC1,FAM208A,CABIN1,TSC1,ZNF184,MARCH8" Drug 2524_DN Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ARRB1,KIF1A,LDLRAD4,CFAP410,PICK1,CSF1,SIPA1L1,PDE4DIP,SPOCK3,CDON,RCAN1,RASGRP2,VPS26C,ADAM28,LILRB4,GUCY1B1,SLC2A6,PADI2,ICA1,MAP4,OXTR,ENPP2,PLCD1,LRRN3,SLC11A1,TSNAXIP1,DDN,LHPP,PLCB1,TAL1,SLC44A1,THRA,SSBP2,XRCC4,ZNF32,SPHK2,SH3GLB2" Drug 4162_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AK2,APAF1,CDC14B,ADAM23,CA4,CALB1,RUNX1T1,CDH2,CRLF1,TPP1,STOML1,SPOCK3,DMPK,HS3ST2,DTNB,MTSS1L,GAD1,HPGDS,GPER1,L1CAM,TAGLN3,ZNF862,NOVA2,NPTX1,TREM2,MAPK7,DCHS2,OGDHL,LIMCH1,FAIM2,NMNAT2,PHLDB1,SYP,DOCK9,XRCC4,FAM13C,JPH3" Drug 4712_DN 0173570-0000 [211245-44-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APC,MARK4,SRSF11,FOXN3,SLIT2,QKI,AKAP7,BAG4,PDE4DIP,BRINP1,JAKMIP2,ZNF804A,DTNA,ACSL4,SCML2,FGFR3,PDLIM5,TXNL4A,HSF2,MIA2,ADAM22,RETREG1,PPARA,RGS12,NEK11,TCP11L1,SH3BP2,FBXO11,KIF13A,CDK19,SUPT5H,TACC1,IQCE,HIRA,ZNF74,KAT6A,TIGD6" Drug 2444_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APBB2,CASK,CDK13,ADAM15,SYNJ2,SCARB1,HOMER3,ARMC8,CREM,OSBPL3,HDAC9,ZNF337,DGKG,SPATA2,TNK2,TUBD1,RASGRP2,FHL1,INPP5K,SPACA9,TJAP1,IL6R,ENPP2,SLC25A23,RAD51D,ZNF493,ZDHHC14,EMID1,RASA3,FAM102A,CCDC88A,NXT2,FBXW11,TLR4,VIPR2,SPHK2,TFIP11" Drug 5385_UP Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AP2A2,ADGRF5,PLA2G4C,ATP2A2,BAIAP3,TAOK2,CNTN1,AKAP5,OSBPL3,RUSC2,DTNA,PDLIM5,DISC1,POLL,PCLO,RASSF8,TJAP1,KCNB1,KCNN1,LIG4,LMO2,SMAD1,PDE4B,PLCD1,MTRF1L,PPP5C,GAL3ST4,RPS6KA2,KCNIP1,SLC2A5,PKNOX2,DOP1A,WSCD1,HIF3A,WIPF1,NT5M,JPH3" Drug 3860_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NME5,SEMA7A,KCNAB2,RGS20,CDK13,SLC4A4,STX16,CAMK2B,STOML1,PICK1,AKAP5,CPS1,NCOR2,FAM169A,DCAF4,DAPK3,FGFR1,FLNC,CAMKK2,FUT9,NEU3,SRCAP,RUNDC3A,SPIN1,GPER1,PCLO,GSN,IL6ST,KPNA5,LSS,MEF2C,KITLG,MMP16,PDE1C,LRRN3,RBM34,SPHK2" Drug 5325_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BRAP,APC,PDE8B,CFLAR,AP4M1,PDE4DIP,DTNA,EGFR,EIF4G2,CDKL3,DLC1,FGF12,GAD1,DISC1,GRIK5,HNMT,DHX35,HSF2,LSS,MPP2,ZNF862,NEK1,NF1,NFYA,NTRK2,SAMD9,ELOVL2,SEC14L1,FNDC3A,BTBD7,ARHGAP26,PLCB1,SLC44A1,XRCC4,ZNF24,TFIP11,MPPE1" Drug 4961_DN "Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APOC1,STX16,ARHGEF7,SCAPER,MTMR2,WASF1,ZMYM4,CREM,DTNA,ACSL4,TXNL4A,CNTRL,BTN2A1,ITPKB,MAPT,MBNL1,KITLG,GIT1,ZNF862,NF1,NFYA,OCRL,PDE4A,PLCD1,RETREG2,MBOAT7,CEP97,ZCWPW1,BTBD7,SLC22A4,TROVE2,EXOC7,BEX4,KAT6B,TRIO,NDRG4,REEP1" Drug 908_DN 5140203; Down 200; 15uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ACTN1,MARK4,MPDZ,SOCS6,PLEKHB1,LRIG1,INTS1,SCML2,DLC1,EFCAB2,CACFD1,MUM1,MATK,MEIS1,PALM,RETREG1,PMP22,LRP12,ELOVL2,PTPRG,CEP97,RPS6KA2,SBF1,EPN2,ZHX3,ZBTB43,TACC1,MCF2L,TRIM2,THRA,CABIN1,CDK20,HIRA,LMF1,MPPE1,ACTR3B,TIGD6" Drug 3038_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "SYN3,ADGRF5,BIN1,LGR5,BMP7,CRLF1,CHRNA4,RAB26,CNTN1,PDE4DIP,RIMS2,SNPH,BRINP1,EPHB1,ARMCX1,KAT8,FGF13,DLL3,B4GALNT1,GNAL,HNMT,SCIN,MBP,ADAM11,ADAM22,NRCAM,PLXNB1,EPB41L4B,MARCH1,MAP6D1,SEMA6D,SPTB,TBCEL,PHF24,PCDHA3,TRO,RPRM" Drug 2875_DN Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NDRG2,MTUS1,AMPD3,KCNAB2,BCAS1,SLC4A4,CFLAR,KRIT1,ARHGEF1,RCBTB2,RAB28,USP6NL,DTNA,HIPK3,ING4,FGFR1,FHL1,PDLIM5,RAB30,HSF2,IL6ST,INPP5B,MAP4,MPP2,STRN3,PPP5C,SLC25A36,SEC14L1,RBM34,SOX3,PLCB1,IQCE,TNS2,KAT6B,UBE3A,PLPPR2,DNALI1" Drug 2223_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "RALGAPA1,C1QTNF1,FAM131A,CFLAR,CACNA2D1,SLC16A4,EPS15L1,CSF1,MAML1,SPOCK2,SPOCK3,MBNL2,NCALD,FHL1,GAD1,ADAM28,RUNDC3A,MSL3,IL6ST,ITPKA,MAN2A2,MAP4,PCBP3,OPRL1,LRP12,MAPK7,GDPD2,PNMA8A,SLC11A1,OGDHL,ZSWIM8,ZNF423,ATP10B,PCDHA5,KAT6B,VGF,NT5M" Drug 6552_DN prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "PPFIA3,PDE8B,SLC4A4,SLC2A11,RGS9,CFLAR,FUBP1,SCARB1,SULT4A1,WHRN,SH2B1,NCOR2,TM9SF4,EXOG,SLC12A6,EPB41L2,EZH1,INPP1,MAN2A2,MEF2C,NEK1,NF1,NRCAM,PLCD1,RGS4,LIMCH1,CLSTN2,STX1A,SYN2,FBXW11,WSCD1,CUX2,TRIM2,AP4E1,ZKSCAN5,HIRA,SLC30A3" Drug 2468_DN Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NDRG2,APBB2,APC,NCOA1,ARHGEF7,SCARB1,ARMC8,CELSR3,COQ7,PDLIM5,INPP5K,COPS8,HTATSF1,NCKAP1L,ATXN2L,KIF2A,MAP4,MEF2C,ZNF862,CNNM2,PTPRN2,TRIM68,SEC14L1,GALNT10,MRAS,SH3BP2,SMARCD3,SNCA,TMCC1,TROVE2,ADGRL3,TCF4,TMPO,TRPS1,FLRT2,LAT2,UBE3B" Drug 5213_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APC,SCAPER,AP4M1,MAGI1,PLEKHB1,CNOT8,SLIT2,QKI,TBC1D5,DTNA,MAMLD1,FEM1B,SUGP2,EGFR,ING4,ENO2,FGFR1,IQCG,MALT1,ELOVL5,HNMT,KCNH2,NPR2,SLC11A2,PLEC,CCDC25,NEK11,TRA2B,ZBTB43,ASTN2,RPGRIP1L,TNS2,DICER1,CHST8,TRIO,MAP3K12,HPS4" Drug 166_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AMT,SEMA7A,KCNAB2,APBB2,BMP7,RAB29,CAMK2G,TPP1,CNTFR,NCOR2,TBC1D5,ACOT8,SUGP2,TUBD1,ETV1,FGFR1,FGFR3,CRCP,GLUL,ADAMTS6,ATXN2L,HMGCR,MBP,NFYA,SLC11A2,NRCAM,NTRK3,CNNM2,CLIP1,SH3BP2,ZKSCAN3,HECW1,SS18,NSFL1C,VGF,NDRG4,REEP1" Drug 2278_DN Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NDRG3,CDC42BPA,KCNAB2,GAS7,FAM131A,ARRB1,PLA2G4C,DNAH17,ALDH7A1,RIPK1,CFLAR,SYNJ2,ARHGEF7,SCAPER,KRIT1,RCBTB2,AKAP7,ABI3BP,GREB1,RIMS2,PLXNC1,FHL1,SEMA4D,MSL3,JAK2,KCNH2,MAP4,MYT1,PDPK1,MINDY2,PRKAR1B,TMEM231,KLHDC8A,PEX26,PPP4R3A,PLCB1,PCDHA6" Drug 3715_DN Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ASIC1,APOC1,CDK13,NRXN3,HAPLN1,NCOR2,SGSM2,EDN1,OPTN,ING4,MRNIP,FGFR1,TRAF3IP2,KCNMB4,ATXN2L,ELOVL5,GIT1,NELL2,NPR2,PDE4B,PIK3R1,MAPK7,WDR25,PTCH1,PID1,TCP11L1,SLC9A5,LIMCH1,SNCA,KDM4B,TSNAXIP1,TBCEL,MGRN1,TIAM1,TNS1,RPRM,VIPR2" Drug 2475_DN Benperidol [2062-84-2]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "DOC2A,BIN1,APC,SLC4A4,ADAM15,SYNJ2,CACNA1A,CCNT1,CNOT8,AATK,DZIP3,ZFYVE16,DTNA,NCALD,PIPOX,F5,PTK2B,DLC1,KAT8,MUM1,KIF2A,MAP4,OXTR,PLCD1,SLC25A23,MAPK7,PTN,FAM214B,SLC11A1,MYH15,DOK5,TROVE2,SUPT5H,ICAM5,KAT6B,GDPD5,PCBP4" Drug 5245_DN Butylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "PLA2G4C,MTMR2,ZMYM4,SRSF11,SLIT2,QKI,CREM,ARHGEF4,ZNF804A,PARD6A,CNNM1,TNK2,ANKMY1,MALT1,FERMT2,GPER1,HNMT,ITPKB,KCNH2,ZNF862,NFYA,PCDH9,PPP2R2B,PPP3CC,PRKAR1B,PTPRE,RIC8B,CLIP1,RXRA,FBXO11,ZNF302,AP4E1,CBX5,ZKSCAN5,GDPD5,UBE3B,SENP7" Drug 5825_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ADD2,AK2,APLP1,PPFIA3,PDE8B,CFLAR,NRG2,NCOR1,INTS1,COQ7,FECH,FAM49B,AHDC1,IL6ST,INPP5B,MEF2C,MEIS1,PDE1C,PLCD1,FSD1,MAPK7,RIPOR1,RPS6KA2,SAFB,PEX26,BTBD7,ZKSCAN3,SMARCA4,COBL,EXOC7,CABIN1,NR2C2,TRIO,UBTF,GDPD5,VPS35L,ST7" Drug 4983_UP Daunorubicin hydrochloride [23541-50-6]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "SYN3,NDRG2,SYT13,APLP1,ADAM15,LDLRAD4,RUNX1T1,RAB33A,HOMER3,CNTN1,CSF1R,CNTNAP2,RIMS2,RIPOR2,SGSM2,HS3ST2,MTSS1L,CD320,SEMA4D,ZNF44,LYVE1,GRM8,KCNB1,MID1,NELL2,NOVA2,P2RY1,PLXNB1,TCP11L1,ZFP2,FUZ,PLCB1,CABIN1,OSBP2,LMF1,VSNL1,ZBTB14" Drug 5205_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AZGP1,SCAPER,BAIAP3,KRIT1,ARHGAP33,ARHGEF6,CSF1R,FAM169A,PHF14,GREB1,DOCK4,ARHGAP24,CDON,MBNL2,EGR3,HSD17B14,NRN1,FHL1,HPCAL4,RUNDC3A,POLL,GRB10,IL6ST,JAK2,MAP2,MBD1,ZNF862,RGS12,SGK1,ASAP3,PKNOX2,SNCA,TRIM2,PCDHGA10,UCHL1,VLDLR,XRCC4" Drug 7201_UP Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ABHD6,BIN1,GAS7,PPFIA3,MARK4,ALDH7A1,SCARB1,MAGI1,LHX2,RAB28,QKI,AKAP12,GIT2,LYPD1,RCAN1,OPTN,MBNL2,COQ7,DENND4A,CDKL3,F8,FGFR1,FHL1,COPS8,GLYR1,CACFD1,TJAP1,PCDH9,STRN3,SAMD9,ZFP30,SNCA,KDM4C,NSFL1C,VIPR2,CLDND1,SEMA3B" Drug 6183_UP trifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "MTUS1,ALK,TRMT9B,BIN1,PDE8B,PTCH2,ATP2B2,SYNJ1,CACNA1I,MYRF,CHRNA4,CSF1,ARHGEF10,RIMS2,SNPH,DAPK3,DBT,MBNL2,MRNIP,RASGRP2,ANKMY1,F5,FAM198B,FGF1,B4GALNT1,PCLO,NFIX,NTRK3,CCSER2,RETREG1,PLCL1,FSD1,CEP41,FBXW7,ARHGEF9,SYN2,PRDM10" Drug 7175_UP Hecogenin [467-55-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BRAP,AP2A2,AK2,AMH,AZGP1,CFLAR,MTMR2,GYG2,RAB29,BAIAP3,ENTPD6,SRSF11,ABI3BP,BAG4,PDE4DIP,DCAF4,DBN1,DBT,MED12,RCAN1,CDKL3,FHL1,TPK1,SEPT9,POLL,LIG4,ZNF862,NTRK2,PRPH,SAMD9,CCDC25,KANSL3,TSPYL2,THRA,TRIO,XRCC4,JMJD1C" Drug 2180_UP Heliotrine [303-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BEGAIN,BIN1,CDK10,ARHGDIG,SLC4A4,GYG2,CFAP410,EPS15L1,MFAP3L,CNNM1,PLXNC1,STX2,ST3GAL6,GAA,KCNMB4,PCLO,GRIK5,KIF5A,NPR2,OPRL1,P2RY1,PCDH9,PMP22,MASP1,PNMA8A,ZNF821,STUM,CPEB3,PKNOX2,SNAP25,SPTB,SPART,CLSTN2,STX1A,KIAA1107,RUNDC3B,PARP11" Drug 6796_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NME5,ALCAM,APBB2,PLA2G4C,SCAPER,CACNA2D2,SLIT2,TPP1,PPP6R2,MFAP3L,TOM1,FAM198B,SCML2,ZNF589,BAIAP2,PDLIM5,SRCAP,GLYR1,GNG4,INPP1,INPP5B,NNAT,PDPK1,PRODH,TMEM104,ZSCAN32,CEP97,RGS3,ZNF821,BTBD7,TSNAXIP1,ZBTB43,TNS2,BHLHB9,VGF,FIP1L1,PHTF2" Drug 6081_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ADD2,BEGAIN,SEMA7A,CDC14B,SEMA4G,ALDH7A1,NRP2,CFLAR,EPS15L1,RGS6,HEYL,PIPOX,FOXF2,TPK1,GNAO1,PRUNE2,STON1,LPAR4,SYNPO,ICA1,C2orf72,KCNB1,KIFC3,MYCN,MTRF1L,PURG,PPP5C,SAMD9,EMID1,SH3BP2,ANKRD6,SLC2A5,KIAA1107,SLC19A3,R3HDM1,VLDLR,FAM13C" Drug 5758_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ACTN1,AP2A2,NME5,BIN1,CDC14B,CDK10,HAPLN1,VCAN,SLITRK5,HDAC4,DAPK3,MFAP3L,CDON,COQ7,FER,OGA,B4GALNT1,SRCAP,GHR,MSL3,IL12A,L1CAM,ZNF862,NDP,NPR2,RETREG1,FAM184A,GAL3ST4,SUGCT,FBXO11,FAM214B,SLC14A1,PHLDB1,DNAH7,TK2,CABIN1,NAV3" Drug 3272_UP SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "C1QTNF1,LTBP4,APC,PPP4R4,CFLAR,FOXN3,COL9A3,RCHY1,CRMP1,RIMS2,PARD6A,FAM49B,GABRG2,RUNDC3A,GLYR1,BTN2A1,ICA1,KHK,SMAD1,GIT1,ELOVL2,ZFHX4,SLC2A5,LIMS2,PKNOX2,SLC11A1,COA1,ZNF423,ZC3H13,TSPYL2,TROVE2,TACR1,WSCD1,TCF4,SLC19A3,VLDLR,SPHK2" Drug 7493_DN ST021200; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ABR,ADRA1D,APC,ARRB1,ADAM15,ADGRB2,ST3GAL5,MTMR2,CHRNA4,HOMER3,CSF1,VCAN,CNTNAP2,TBC1D5,DBT,IRAK4,ZNF589,FHL1,ANKFY1,SHISAL1,TJAP1,JAK2,MAPT,MIA2,NFYA,PFKFB2,PLEC,MINDY2,PPP5C,RAD51D,TCP11L1,BTBD7,ZNF667,SPTB,SSBP2,ZNF45,UPF3A" Drug 3474_DN Methazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APBB2,CDC14B,CRLF1,SOCS6,TPP1,HOMER3,CRY2,FAM169A,DNM1,TOM1,MAMLD1,SEMA4D,TRAF3IP2,DISC1,INPP5K,IPO5,PAXBP1,LYRM9,PRPH,TMEM104,ELOVL2,ZSCAN32,SBF1,BTBD7,ZKSCAN3,MAPKBP1,CAMTA2,ELOVL4,TTBK2,PLCB1,EXOC7,TPM1,CDK20,WBP2,UBTF,KCNK12,SMIM8" Drug 6247_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "CDC42BPA,KCNAB2,BCAS1,MARK4,ADAM23,CFLAR,SYNJ2,RAB29,ARHGEF2,CRLF1,CHN2,QKI,CTH,MFAP3L,DTNA,SUGP2,EGFR,ACSL4,DLC1,FER,FHL1,B4GALNT1,GLYR1,GRIK5,IL6ST,MID1,POLG,CEP97,RAP1GDS1,RPS6KA2,WDR47,SMARCC2,SPTAN1,CDK19,TPM1,VLDLR,MPPE1" Drug 3408_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "EPB41L5,STOML1,VAX2,ABCG1,SIPA1L1,FBXL5,EXOG,DTNA,SUGP2,EIF5,POLR1B,FAM49B,CSPG5,ZNF44,SRCAP,PRRC2B,GRB10,KCNF1,ZNF862,OPA1,PRPH,TMEM104,RNASEL,CCDC25,SBF1,ARFGAP1,RCOR3,MAPKBP1,PDZRN3,TROVE2,POGZ,SS18,TNS2,CABIN1,HIRA,NDRG4,HPS4" Drug 843_DN 5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "MTUS1,BIN1,OGT,CDC42BPA,APC,SYNJ2,SPAG9,B4GALT6,QKI,LYPD1,PARD6A,EGR3,COQ7,MTSS1L,CDKL3,RACK1,ST3GAL6,TRMO,SEPT9,GHR,SPIN1,GPER1,IDH3B,CNOT4,PIK3R1,STRN3,PRKAB2,RET,SYT1,TIAM1,BEX4,CDK20,TRIO,HIRA,RPRM,ZNF45,MPPE1" Drug 6828_DN Piretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "DOC2A,BIN1,CDC42BPA,BCAS1,PPFIA3,MARK4,NCOA1,GYG2,PLAA,QKI,CSF1R,FAM169A,RIMS2,DNM1,ERBB2,EXTL2,ZNF589,OGA,ERAP1,GLYR1,JAK2,MAPT,CNOT4,PPP5C,ZCWPW1,RGS12,CCDC25,RPS6KA2,KIF16B,SLC9A5,COA1,KDM4C,PLCB1,ZKSCAN5,RPRM,VGF,HPS4" Drug 2568_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APBB2,GAS7,CDK13,ADAM15,CAMK2G,CNOT8,SIPA1L1,DTNA,PRKAG2,TPK1,CSPG5,COPS8,LILRA2,ITPKB,TM6SF1,NFYA,SLC11A2,OPA1,PDE4B,KCTD15,NLE1,SNRK,TMEM231,ZDHHC14,PPP4R3A,CCDC88A,ZNF667,DDN,SS18,NXT2,PDLIM2,TBL1X,PARD3,TSN,SSBP2,ZNF74,KAT6A" Drug 2884_DN Clorsulon [60200-06-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "CDC42BPA,SLC4A4,SYNJ1,ARHGEF2,CSF1,CNTNAP2,MFAP3L,EXOG,SLC12A6,SUGP2,VPS13B,EZH1,FGFR1,DISC1,GPD2,TDRKH,TJAP1,IL6ST,INPP1,MAP4,SLC11A2,LRP12,MBOAT7,ZSCAN32,ZNF821,EPN2,BTBD7,CXXC4,SNCA,RBM34,ELOVL4,CRTC1,PCDHA6,TRIO,UBE3A,VIPR2,LMF1" Drug 5676_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "RALGAPA1,ADD2,BEGAIN,SLC4A4,MTMR3,GYG2,CALB2,CD86,CRYM,CSF1,SPOCK3,DTNA,HIPK3,F5,KHDRBS3,GAD1,ERAP1,DISC1,SRCAP,LPAR4,CACFD1,HLF,KCNH2,KPNA5,MGAT3,NCF2,NPTX1,TMOD2,PGAM2,NLE1,PLCD1,GRAMD1C,SBF1,ZNF821,EPN2,TNS1,TRIM9" Drug 7198_DN Podophyllotoxin [518-28-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AK2,ARHGDIG,FOXN3,RAB28,HOMER3,PICK1,CREM,LRIG1,MED12,PHF20L1,EIF4G2,ZNF589,SESN1,GLYR1,MUM1,KHK,SCAMP5,NF1,CNOT4,OGG1,PCDH9,PRKAR1B,PTCH1,CEP97,RAD51D,SGK1,SH3BP2,SPATA7,ZHX3,UNC5B,DIP2A,ARHGEF9,EXOC7,IQCE,RPRM,HPS4,TIGD6" Drug 5297_DN Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ADD1,APC,ARRB2,ADAM15,CFLAR,PLAA,CREM,CSNK1E,ZNF337,C2CD2L,CELSR3,EIF5,CDKL3,TRMO,CSPG5,INPP5K,TXNL4A,MUM1,TJAP1,INPP5B,ZNF862,NEK1,NPR2,PDE4A,RETREG1,PRPH,RAD51D,CCDC25,MAPK12,TSPYL2,VGF,VIPR2,ZIC1,REEP1,MAP3K12,EPM2A,SMIM8" Drug 2432_DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ABHD6,BRAP,CASK,MARK4,NCOA1,SCAPER,CACNA1A,RAB33A,PLAA,SH2B1,KIAA0586,RUSC2,TNK2,F5,ST3GAL6,PDLIM5,ALDH1L1,SRCAP,USP19,ZNF862,NF1,CNOT4,PLCB2,PPP3CC,CNNM2,DEF8,ZCWPW1,ZDHHC14,SH3BP2,CCDC88A,ARFGAP1,SMARCD3,DDN,JMJD6,FBXW11,MAP3K12,UBE3B" Drug 2895_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "KCNAB2,APBB2,AQP6,CFLAR,SCAPER,BAIAP3,CACNA2D1,CAMK2B,CDO1,CLGN,TAOK2,CPS1,NCOR2,AATK,SPOCK2,JAKMIP2,GSDME,DLC1,GRIK5,HLF,ICA1,KIT,MSI1,PLEC,LRP12,PRODH,SAMD9,KLHL11,EMID1,IQSEC2,ATP10B,KIAA0930,PCDHA6,HIF3A,TMEM121,TPM2,KCNK12" Drug 2864_DN Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AMT,APC,SEMA4G,SYNJ2,CA4,ARHGEF1,SCARB1,FAM189A2,HOMER3,AKAP7,DCAF4,DAPK3,SLC12A6,TSPAN5,CELSR3,MRNIP,FGFR1,IQCG,ANKFY1,NOP56,FAM49B,ZNF44,SRCAP,CACFD1,INPP1,LIG4,MAP4,RETREG1,RETREG2,MBOAT7,RAD51D,SH3BP2,EPN2,THSD1,DNALI1,HPS4,ST7" Drug 1687_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ASPHD1,LTBP4,CDK10,ARRB1,ARRB2,NUMB,CFLAR,BMP7,QKI,HOMER3,CREM,CRY2,DBN1,DBT,DNM1,FER,FGFR3,CSPG5,SYT17,FICD,RNFT2,INPP5B,LIG4,SLC11A2,ELOVL2,PTK2,RXRA,KIF16B,EPN2,JMJD6,TACC1,TRIM2,DOCK9,CDK20,HIRA,SMIM8,ACTR3B" Drug 4552_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "AMT,ATP6V0A1,SCAPER,MTMR3,GYG2,NRG2,DAPK1,SPOCK2,C2CD2L,IRAK4,ING4,RCAN2,ETV1,FGFR1,HPCAL4,AGAP2,ERAP1,SIGLEC8,RUNDC3A,GLYR1,ADAMTS13,ATXN2L,ICA1,ITGA7,KCNN1,KPNA5,MGAT3,LYRM9,NF1,PDE4D,POLG,CNNM2,PTPRH,PTPRN2,ZNF423,CEP68,SSBP2" Drug 541_UP Iressa; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ADORA2A,APBB2,ARRB2,ATP2B2,SYNJ2,CARS,DLGAP1,CHN2,STOML1,FAM189A2,CTH,SPOCK2,C2CD2L,ING4,PTK2B,SCML2,ZNF589,FYN,ERAP1,GRB10,NXPH3,INPP5B,NTRK3,P2RX7,PLCD1,CCDC40,GAL3ST4,ST6GAL1,ZSWIM8,CDK19,SPART,SSTR2,PHF24,KAT6B,VGF,VLDLR,SLC38A1" Drug 2868_UP Phenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "SYN3,AP2A2,AMPD3,BIN1,PROM1,CACNA1I,CA4,CALB2,CAMK2B,ARHGAP33,CRMP1,KLHL3,EDNRB,C3orf18,HSD17B14,ERCC2,ZNF391,FAM198B,PDLIM5,DISC1,GRIK5,TJAP1,KCNB1,ADAM22,NPTX1,TMOD2,PLTP,SH3BP2,SLC8A1,SMG6,PCDHGB6,OBSL1,CRTC1,SLC44A1,TNS1,PRDM10,KCNAB1" Drug 4309_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ACHE,ALK,BEGAIN,PPFIA4,APAF1,CDC14B,CDK10,CA12,CAMK2B,CBS,CABP1,COL9A3,CSNK1E,PDE4DIP,RIPOR2,SNX29,TENM1,ETV1,FGF1,ZNF44,SEPT9,GLYR1,ADAMTS13,MYCN,CNOT4,NTRK2,PDE4A,PFKFB4,MAPK7,ZSCAN2,RGS4,SH3BP2,CNKSR2,SLC11A1,IQSEC2,DDN,TPM1" Drug 5631_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NDRG2,BIN1,APC,CFLAR,MTMR3,CBFA2T2,CLGN,SLIT2,STOML1,QKI,CRY2,SIPA1L1,JAKMIP2,TOM1,MRNIP,SCARA3,PRELID3A,GLYR1,GRB10,RASSF8,INPP5B,MAP4,ZNF862,PPARA,PRPH,PTCH1,NKAIN1,KCTD17,NEK11,RPS6KA2,COA1,KDM4C,PARD3,CDK20,RUNDC3B,ZKSCAN5,KCNK12" Drug 2106_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APC,MARCH3,CFLAR,RCBTB2,HOMER3,HINFP,CSNK1E,PPP6R2,TBC1D5,MATR3,KIAA0753,KLHL3,SPOCK3,COQ7,ZNF589,BAIAP2,CSPG5,HTATSF1,ACOT7,INPP5B,NFYA,SETD4,PLCD1,POLG,TMEM231,RPS6KA2,SBF1,ST6GAL1,SMARCD3,SS18,EXOC7,ZNF34,METTL3,SMUG1,TRIO,MPPE1,PHTF2" Drug 2255_DN Pentylenetetrazole [54-95-5]; Down 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "NDRG2,AP2A2,BEGAIN,AMPD3,BIN1,AMT,GAS7,RASL11B,ATP6V0A1,SYNJ1,GYG2,CFAP410,HOMER3,BAG4,TOM1,EGFR,FGF12,FHL1,SRCAP,GLYR1,POLL,GRB10,KCNN2,TM6SF1,MAPK7,ZDHHC14,RGS3,RNASEL,SH3BP2,SLC22A4,RBM34,PLCB1,ZNF34,CABIN1,KCNK12,SLC30A3,KCNAB1" Drug 3323_DN Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APC,APOC1,CDK10,PLA2G4C,ADAM15,CFLAR,FUBP1,CA4,SPAG9,GREB1,EDNRA,ING4,STX2,VPS26C,SEPT9,RAB30,CNTRL,LSS,GIT1,NFYA,CNOT4,OCRL,OGG1,PLCD1,PRKAR1B,RAD51D,RGS12,ZKSCAN3,SS18,RPGRIP1L,PCDHA6,AP4E1,HIRA,VLDLR,CLDND1,KCNK12,ZNF45" Drug 2149_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "BEGAIN,BIN1,ADGRB1,FUBP1,CACNA2D1,RAB26,DAPK1,RUSC2,SGSM2,DTNA,FAM13A,EIF1,FGFR1,FGFR3,FHL1,CGREF1,INPP5K,ZNF276,GRM2,PADI2,MAN1B1,IL6ST,MAP4,TAGLN3,ZNF862,CEP41,ZCWPW1,ZFHX4,NEK11,RPS20,FAM102A,SNCA,CEP68,TBL1X,SLC35G2,RPRM,SLC17A7" Drug 5923_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "ASIC1,ADORA2A,BIN1,APBB2,GAS7,PDE8B,ADAM15,PLAA,TPP1,CTH,MFAP3L,RUSC2,DTNA,PLXNC1,RASGRP2,DLC1,FER,FGFR1,FYN,ELOVL5,KPNA5,ADAM22,ZNF862,NNAT,PLEC,MBOAT7,SAMD9,WDR25,PTPRN2,FBXW7,ZNF821,ASAP3,FAM214B,ELOVL4,LAT2,XRCC4,SLC30A3" Drug 7381_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 9.44E-03 1.06E-01 37 195 "APBB2,MARK4,ATP2A2,SYNJ2,ARHGEF2,CLCN3,HOMER3,IQCK,RCHY1,NCOR1,PPP6R2,ING4,TNK2,STX2,VPS26C,ST3GAL6,ZNF589,TRMO,FYN,TMEM8B,INPP5K,FAM69A,KHK,SCAMP5,SERPINI1,STRN3,POLG,FSD1,SCN8A,AMBRA1,SLC6A8,FNBP1,CDK19,DIP2A,EXOC7,DNMBP,ZBTB14" Drug ctd:C076994 perfluorooctane sulfonic acid CTD 1.19E-03 1.00E+00 9.46E-03 1.07E-01 224 1630 "RALGAPA1,ACADM,ACHE,CLK4,ADORA1,ADRA1B,OSBPL1A,OSBPL8,AK2,ALCAM,AMPD3,AMPH,CDC42BPA,APOC1,APOC2,PPP4R4,ARNTL,PLA2G4C,STK33,ASPA,ATP1A1,ATP1A3,ATP2B2,DOCK11,MPDZ,BCHE,IL33,CACNA1A,DDR1,CAMK2A,CAMK2G,CAST,CBR1,ZNF501,KRIT1,MTMR7,SCARB1,ARHGAP33,CDO1,CLGN,SRSF11,NGEF,ABCG2,SULT4A1,COX4I1,MYRIP,NECTIN3,CPS1,RBM39,NCOR1,ABCG1,CS,DZIP3,CTH,ZFYVE16,INTS1,SPOCK2,DBI,DBN1,SACS,MTX3,NR1D2,DMTF1,CASP8AP2,OPTN,PHF20L1,EGFR,AASS,KCTD3,ENO2,RCAN2,ERBB2,F5,F8,ABCA8,ACSL4,DLC1,FDFT1,FGFR3,POLK,ATP5PD,FOXO3,FLT1,SMC2,UFM1,CAMKK2,ZMAT1,GAA,IQGAP2,CPLX1,GCK,ALDH1L1,GCNT2,GFRA2,PPARGC1A,MALT1,DHRS4,BRD8,TNRC6A,GLUL,ZNF638,GPD1,CNTRL,GRIA2,PLCD4,GSTT2,HBA1,ELOVL5,ACOT7,HMGCR,HP,LRRCC1,IL6ST,ITPKA,JAK2,KCNN2,KTN1,LIG4,PAXBP1,HECTD2,LSS,MAPT,MAT2A,MBNL1,MEF2C,MEIS1,MEST,ZNF680,NRBP2,ZNF92,NEK1,NFE2L2,ALDH1L2,NUCB2,CLDN11,CNTN3,PDE3A,ENPP2,ABCB1,PIK3R1,SNX10,XRN1,PKM,STRN3,POLG,PPARA,PPP1R1A,PPP3CA,PRKCB,MAPK3,GRAMD1C,PRPH,MASP1,SAMD9,VPS13C,PSMA6,PTH1R,PTK2,PTPRD,USP47,OXR1,REV3L,MRPS18A,SLC25A36,ZFHX4,CCDC82,LRRK2,MEG3,ZNF354C,CCDC112,AP1AR,RMI1,S100B,MAPK12,SATB1,SCP2,SH3BGR,KIF21A,HKDC1,CHD9,FNDC3A,CCDC88A,INAVA,KIF13A,BDP1,UHRF1BP1L,SPP1,RBM26,PBLD,ITPRID2,ZNF302,SAMSN1,SSTR2,LARP4,SS18,SSPO,ERBIN,ADHFE1,VPS13A,SYN1,SYP,TCF4,ZEB1,TRIM2,TEK,DICER1,CDH22,THRA,ACTR6,TPM1,CCDC14,VSNL1,RICTOR,MICU3,KCNT2,ZNF540,ZNF138,SMARCAD1,EVI5,TRIM16L,ZNF37BP,JMJD1C,SRGAP2B,SENP7" Drug 7073_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.21E-03 1.00E+00 9.59E-03 1.08E-01 34 175 "ADRB2,ARNTL,ST3GAL5,ABCG1,PDE4DIP,CTH,PLPPR4,PARD6A,RGS17,TBC1D16,TAOK3,BAIAP2,PDLIM5,FYN,GUCY1B1,MAPT,MMP16,TAGLN3,PALM,PCDH9,SERPINI1,RETREG1,PRPH,RBBP6,RGS4,SH3GL3,KDM4B,SPTAN1,RGL1,SYT1,KIAA0930,SSBP2,TRIM9,DPF3" Drug 2452_UP Vigabatrin [60643-86-9]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-03 1.00E+00 9.59E-03 1.08E-01 34 175 "NDRG3,BEGAIN,APBB2,CDK13,DNAH17,CFLAR,BMP7,CD86,CD38,CHN2,COL9A3,CLOCK,CREM,ABCG1,SIPA1L1,DOCK4,ERBB2,BAIAP2,PRKAG2,TRAF3IP2,NEU3,AFF1,MMP17,MX1,NF1,P2RY1,PDE4A,PDE4B,BCAS3,WDR25,FRMPD1,SLC11A1,ATP10B,TPM1" Drug CID003034155 reductone Stitch 1.23E-03 1.00E+00 9.79E-03 1.10E-01 10 30 "APOC2,ALDH7A1,CDO1,DBI,ENO2,L1CAM,XRN1,APTX,XPO1,NETO1" Drug CID000643668 discodermolide Stitch 1.23E-03 1.00E+00 9.81E-03 1.11E-01 11 35 "NCOA1,NCOR1,NCOR2,TUBD1,TUBB3,TUBA8,GPR162,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug 1663_DN "ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.24E-03 1.00E+00 9.89E-03 1.11E-01 35 182 "AK2,LTBP4,SYNJ2,CA12,EPS15L1,GREB1,TBC1D5,RHOBTB1,DNM1,RASGRP1,EGR3,ENO2,EFCAB2,INPP5K,SRCAP,CNTRL,JAK2,KCNF1,MAP4,MAPT,NF1,NPR2,PLEC,SMOX,ELOVL2,RBBP8,RET,SGK1,FAM102A,EPN2,DHX30,ZBTB43,TROVE2,ZBTB14,SEMA3B" Drug CID000002524 1-alpha-25-dihydroxycholecalciferol Stitch 1.25E-03 1.00E+00 9.91E-03 1.12E-01 133 909 "ADRA1B,ADRB2,MTUS1,SPARCL1,AMH,MARCH3,NCOA1,ATP2A2,ATP2B2,RIPK1,BBS2,SCAPER,CA4,CA8,CA12,CACNA2D1,CALB1,CALB2,CALM1,CH25H,CD86,SCARB1,CD38,DLGAP1,B4GALT6,STOML1,CNTFR,COL9A1,COL9A3,NRG2,AKAP12,NCOR1,NCOR2,CSF1,CSF1R,PLCXD3,BOC,DOCK4,KIF26A,GSDME,FAM107B,PDCD6IP,ARRDC4,SEZ6L2,TSPAN5,EDNRA,KLHL5,EGFR,CALCRL,ENO2,ERBB4,ADGRV1,FAM198B,TAOK3,ST3GAL6,FGF1,BAIAP2,AGAP2,AGAP3,ATP2C1,ZNF44,MSTN,ADAM28,GFRA2,CSDC2,MALT1,PLCD4,GSTM5,GSTT2,HAS2,PADI2,TNFAIP8L3,IGF1,IL6ST,IL12A,ITGA7,ITGAM,CREG2,IPO5,LAMA2,LIFR,KITLG,MITF,MSR1,MYO5A,NELL2,NTRK2,NTRK3,OXTR,PCSK5,PDE4B,ABCB1,PKM,PLCB2,PLCD1,STRN3,PPP3CA,PRKCB,MAPK3,LAMA1,SNRK,PTH1R,PTPRO,MARCH1,RET,GSTCD,RXRA,SAFB,SEMA6D,SEC14L1,SH3GL3,CHD9,SYBU,ST8SIA1,LIMCH1,TMCC1,KDM4B,PDZD2,SPP1,CAMTA2,SEPT8,PLCB1,SYT1,TCF12,KAT6B,CA14,VSNL1,KCNT2,TUBA1A,SEMA3B,NAV3,WNK2,EPM2A" Drug CID000008058 hexane Stitch 1.26E-03 1.00E+00 1.00E-02 1.13E-01 17 68 "RALGAPA1,ABHD6,AMT,ARSE,CRYM,PITPNM3,GREB1,POLK,CDH20,ASPRV1,MID1,NEFM,PDCD2,CLSTN2,GPR161,TP53BP2,GAN" Drug ctd:D016578 Crack Cocaine CTD 1.26E-03 1.00E+00 1.00E-02 1.13E-01 17 68 "LDB2,CLTB,DYNC1I1,ENO2,ST3GAL6,GAD1,GNAO1,GSN,TAGLN3,NEFM,SEPT4,PRKCB,MAPK3,MAPK10,PTK2,PTN,UCHL1" Drug CID000024460 lead chromate Stitch 1.27E-03 1.00E+00 1.01E-02 1.13E-01 22 98 "ASIC1,NT5C3B,ALDH7A1,CFLAR,C5,CACNA1A,CACNA2D1,KRIT1,DBI,ERCC2,CRCP,SLC11A2,PPP3CA,PPP3CC,PRKCB,PTK2,DPF2,COPZ1,RADIL,SLC11A1,CABIN1,SLC30A4" Drug CID000023926 lanthanum Stitch 1.27E-03 1.00E+00 1.01E-02 1.14E-01 28 136 "ADCY5,ADCY6,ADCY8,ATP2A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CCK,KRIT1,ENTPD2,CACNA2D2,CABP1,PTK2B,ATP2C1,MAP4K5,KCND1,PKD1,MAPK3,MAPK4,MAPK7,GSTCD,RYR3,TPCN2" Drug 3231_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "NDRG2,NME5,APOC1,CDK13,ADGRB3,CALB2,HIP1R,CD86,TPP1,WHRN,NRG2,HAPLN1,VCAN,RIMS2,SPOCK2,FGFR1,PRELID3A,SRCAP,TDRKH,GRB10,GUCY1A1,IL6ST,KCNJ5,NPTX1,LRP12,PPARA,PPP5C,MAPK7,GDPD2,TCP11L1,RPS6KA2,PEX26,ATP10B,TBCEL,WSCD1,TRIM2" Drug 2832_UP Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "ADORA2A,NME5,PPFIA3,NRP2,CFLAR,CACNA1I,FOXN3,WHRN,RASSF2,DBT,TMCC2,EXOG,SUGP2,FGFR1,OGA,MSL3,TDRKH,IL6ST,INPP1,KCNH2,MITF,AFDN,ZNF862,PLCD1,C1orf54,RGS4,RGS12,FBXW7,KCNIP1,ASAP3,ATP10B,PLCB1,WSCD1,AP4E1,PLPPR2,PARP11" Drug 2231_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "NME5,AK2,ALK,FAM131A,ADGRB2,CFLAR,MTMR2,LDLRAD4,CFAP410,GREB1,RASSF2,MAML1,DMPK,MBNL2,IRAK4,SPEG,DLC1,FGF1,OGA,ZNF44,ERAP1,ALDH1L1,IL6ST,KCNJ5,MAP4,ADAM22,PALM,PAX6,PCDH9,ASAP3,CPEB3,JMJD6,R3HDM1,CA14,UBE3A,ITM2C" Drug 3214_DN "Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "DOC2A,APBB2,PPFIA3,ARHGDIG,ARNTL,MARK4,USP2,QKI,HOMER3,WHRN,CREM,MRNIP,CDKL3,BAIAP2,USP19,DBF4,HSF2,MAP4,MATK,MITF,GPSM2,PLXNB1,SPDL1,RGS12,NEK11,MAP6D1,EMID1,TRA2B,ZFP30,ZKSCAN3,KDM4B,SPTAN1,JMJD6,ZNF34,TMPO,XRCC4" Drug 5413_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "ALK,APAF1,GAS7,APOC1,CDC14B,CFLAR,GYG2,CACNA1I,CAMK2G,QKI,FHL5,ARHGAP24,DTNA,OPTN,EGR3,ETV1,PTK2B,FHL1,SRCAP,GLYR1,RASSF8,ATXN2L,MSR1,MYO7A,MAPK10,PTPRE,STUM,ASAP3,PLCB1,MCF2L,TRIM2,RPGRIP1L,ZNF34,ZKSCAN5,SEMA3B,SLC17A7" Drug 5455_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "CHN2,CPS1,MFAP3L,DTNA,DUSP9,HIPK3,FAM198B,SCML2,FGF1,PRUNE2,KCNJ5,KIT,MAP4,MITF,NF1,PFKFB2,PPP2R2B,MAPK10,SAMD9,VPS13C,SH3BP2,FAM214B,ARHGEF40,ARHGAP26,TNS1,TRIO,TRO,FAM155A,UCHL1,VSNL1,WIPF1,SLC30A3,DNALI1,PRDM10,SLC17A7,KCNAB1" Drug 2695_UP genistein; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "AZGP1,CACNA1G,SLC16A4,CD86,CDO1,COL9A3,NRG2,CREM,ARHGEF10,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,DGKG,EDN3,MBNL2,EGR3,FER,GCNT2,LYVE1,GLI2,PRUNE2,RASSF8,ADAM22,CCDC40,RASGRF1,KLHL11,SUGCT,S100B,ZNF415,ARC,TRPS1,KCNK12,MAP3K12,EVI5,JPH3" Drug 7206_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "AK2,APLP1,DDO,PLA2G4C,BAIAP3,CA4,ARHGEF2,CLGN,NRXN3,BAG4,OPTN,EGR3,DLC1,BAIAP2,FHL1,FYN,GCNT2,SRCAP,GRB10,RASSF8,SYNPO,ICA1,ITPKB,MGAT3,MIA2,KITLG,AFDN,MSI1,EMID1,FRMPD1,SYBU,KDM4C,ARHGEF9,PCDHGA10,PHTF2,RNF170" Drug 2300_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.28E-03 1.00E+00 1.01E-02 1.14E-01 36 189 "NME5,CDC42BPA,APBA2,ARHGDIG,KALRN,AKAP7,WHRN,SIPA1L1,GREB1,RASSF2,SPOCK2,KLHL3,ELN,RASGRP2,MTSS1L,F5,AGAP2,SRCAP,GFER,LPAR4,GRB10,GUCY1B1,ICA1,KITLG,MSI1,NF1,NNAT,SMIM7,PTPRE,OGDHL,SNCA,ZBTB43,JMJD6,TPM1,LAT2,PHTF2" Drug CID000004367 L-NNA Stitch 1.29E-03 1.00E+00 1.02E-02 1.15E-01 44 244 "ADORA1,ADORA2A,ADRB2,AGT,ALDH7A1,CA4,CACNA2D1,CALM1,KYAT1,CCK,DMPK,EBF1,EDN1,EDN3,EDNRA,EDNRB,FLT1,PDLIM5,GCNT2,PPARGC1A,CRCP,KCNMB4,GRIN2C,GRIN2D,CIT,GUCY1B1,HBA1,TNFAIP8L3,CPT1C,IGF1,KCNN1,KCNN3,NBL1,NPY,NPR2,OXTR,P2RY1,PDCD2,PTN,PEG10,TACR1,AGTPBP1,SIRT1,VIPR2" Drug CID000013245 AC1MMLID Stitch 1.29E-03 1.00E+00 1.02E-02 1.15E-01 21 92 "SLC24A4,ATP1A1,ATP2A2,ATP2B2,CALB1,CALM1,KRIT1,CRMP1,EDN1,EIF4G2,ATP2C1,SLC11A2,FXYD1,PPP3CA,PPP3CC,SLC6A11,SLC8A1,SYT1,GPR161,CABIN1,SLC17A7" Drug 1793_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.29E-03 1.00E+00 1.02E-02 1.15E-01 33 169 "ABHD6,ADRB2,ARNTL,ST3GAL5,HIP1R,SPAG9,ABCG1,CTH,FAM13A,TAOK3,BAIAP2,FYN,BACH2,FAM69A,PCDH9,PMP22,PTX3,RGS4,RPS6KA2,SH3GL3,CCDC88A,KDM4B,DOP1A,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,COBL,AGTPBP1,HEY1,DPF3" Drug 1000_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.29E-03 1.00E+00 1.02E-02 1.15E-01 33 169 "NME5,ST3GAL5,BAIAP3,CLGN,PDE4DIP,ARMCX2,JAKMIP2,STX2,BAIAP2,FYN,CYP46A1,RAB40B,STON1,MPP2,NEK1,PCDH9,SERPINI1,PKIA,PRPH,PTCH1,RPS6KA2,SH3BGR,SH3GL3,WDR47,THSD1,ELOVL4,RGL1,STXBP1,TRIM2,HEY1,RUNDC3B,SSBP2,SLC17A7" Drug ctd:C005460 uranyl acetate CTD 1.30E-03 1.00E+00 1.02E-02 1.15E-01 46 258 "ACHE,NDRG2,APC,BCHE,NAE1,CBS,CBFA2T2,APPL1,CTH,PUM1,SNAP91,CHRDL1,PDCD6IP,DTNA,VPS13B,SRRM1,SEC24B,EVL,IQGAP2,GLUL,KDM2B,STMN2,SMAP1,LAMP2,STMN1,NCOA7,NFE2L2,PFKFB4,PIK3R1,PTK2,RDX,RPL15,BAALC,RMI1,SCN2B,SCP2,COA1,KDM4B,DNAJC9,NEIL2,VSNL1,NDRG4,REEP1,DPYSL5,EVI5,TUBA1A" Drug CID000061605 Rubidium chromate Stitch 1.30E-03 1.00E+00 1.02E-02 1.15E-01 18 74 "SLC24A4,ATP1A1,ATP1A3,ATP1B3,BLM,NAE1,SLC12A6,KCND1,KCND2,KCNH2,KCNJ5,KCNK3,P2RX7,SLC12A2,SLC12A4,RIMBP2,SMUG1,SMARCAD1" Drug 3842_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "DOC2A,BIN1,MARK4,MPDZ,TAOK2,TPP1,AKAP12,CSF1,RIMS2,DAPK3,DNM1,MBNL2,COQ7,NCALD,ZNF589,GLYR1,STON1,KITLG,ADAM22,NFYA,PLCD1,PRKAR1B,SNRK,ENOX1,RGS12,SH3BP2,ASAP3,FNDC3A,PEX26,TTBK2,PLCB1,RPGRIP1L,ZKSCAN5,FAM155A,ST7,PHTF2,RNF146" Drug 5226_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NME5,SEMA6A,ANK2,SLC2A11,CFAP410,CACNA1A,KALRN,USP2,CDH2,ARHGAP33,SULT4A1,CNN3,SIPA1L1,RUSC2,CDON,RASGRP2,EZH1,KHDRBS3,MSL3,GRIK5,SLC2A6,RASSF8,ADAM22,NNAT,SLC25A23,SAMD9,KLHDC8A,NEK11,KANSL3,RBM26,PHLDB1,TACR1,PCDHA5,TMPO,AMACR,KLC2,TIGD6" Drug 1952_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HG-U133A" Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "SEMA4G,CLDN10,CLTB,PICK1,PARD6A,DTNA,ETV1,ZNF589,SCARA3,POMT1,MSL3,GPR37,ADAMTS13,AGBL5,IFI16,NFIX,NFYA,VPS13C,TMEM104,RNASE1,TRA2B,ARHGEF40,SLC11A1,CDK5RAP2,LIMCH1,ZHX3,ZC3H13,ST5,PHLDB1,STX1A,MLST8,PIK3R5,TSN,TSC2,LAT2,ZNF24,SMIM8" Drug 4697_DN Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AK2,BIN1,CDC42BPA,APBA2,APC,MARK4,CA12,ARHGEF2,SLIT2,QKI,AKAP7,SH2B1,ARHGEF4,SGSM2,DTNA,EDNRA,SEPT9,TDRKH,GRM8,KIF2A,MAP4,MIA2,NCAM2,NF1,SMIM7,PPARA,ZNF821,BTBD7,ZHX3,ARHGAP26,ARC,TNS2,PARD3,TRIO,VIPR2,EVI5,TIGD6" Drug 4335_UP Indapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AQP6,CDC14B,BMP7,ST3GAL5,SLC16A4,PDE4DIP,CNTNAP2,C2CD2L,ZNF549,APC2,DLC1,KAT8,DENND2A,FERMT2,GRIK5,ITGA7,KCNB1,KCNJ5,MAP4,NPTX1,NTRK2,PRKAB2,CEP41,CCDC40,ENOX1,RFX2,TCP11L1,SEC14L1,SP4,HECW1,IQSEC2,LHPP,DMXL2,THRA,TIMP4,CDK20,NT5M" Drug 3471_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABHD6,NDRG3,ALCAM,CDC42BPA,FAM131A,BCAS1,CFLAR,KRIT1,HOMER3,CREM,CRY2,CTH,PPP6R2,HIPK3,TNK2,GPHN,SEMA4D,ANKFY1,GCNT2,GLYR1,HNMT,NF1,SETD4,PDE4A,SLC25A23,SMIM7,ZSCAN32,ZCWPW1,NEK11,LIMCH1,SPART,TROVE2,CAMTA2,ELOVL4,SIN3B,MAP3K12,MPPE1" Drug 3623_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NME5,C1QTNF3,DOC2A,AMT,APLP1,PPP4R4,SLC4A4,STX16,ATP6V0A1,BMP7,CLGN,NCOR1,DMPK,DTNA,CNNM1,BAIAP2,CINP,SLC2A6,IL6R,MMP16,MPP2,SLC25A23,TMEM104,RIPOR1,ZDHHC14,RGS12,KCTD17,GSTCD,FAM214B,SLC6A8,STX1A,TBCEL,SMG6,KIAA0930,FLRT2,KLC2,EVI5" Drug 1840_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ACTN1,PPFIA4,MARK4,N4BP2L1,ATP6V0A1,SCAPER,CACNA1A,SRSF11,RAB33A,SLITRK5,DAPK1,SPATA2,PLXNC1,ZNF589,OLFM1,ALDH1L1,GLYR1,RAB40B,TJAP1,KCNQ3,MAP4,SCAMP5,GIT1,MINDY2,CNTLN,RGS3,RPS20,SEMA6D,FAM214B,BTBD7,DOK5,ZHX3,SLC19A3,REEP1,ADAMTS9,ST7,PHTF2" Drug 419_DN chlorpromazine hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "EP400,AQP6,PLEKHB1,SOCS5,KCTD3,TUBD1,STX2,ZNF589,FGFR3,SCARA3,SEC23B,DBF4,ADAMTS6,SCIN,KTN1,LAMP2,MARK3,MBD1,ADAM22,MYO6,SLC11A2,NLE1,STRN3,PPM1B,RIPOR1,SH3GL3,SLA,ELMO2,FNBP1,NMNAT2,SPART,ATP10B,VPS13A,COBL,VIPR2,ZNF195,MPPE1" Drug 609_DN 5666823; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AP2A2,AMPD3,APBB2,RIPK1,CFLAR,GYG2,SOCS6,ARHGEF6,KLHL3,TMCC2,DRP2,MAMLD1,FAM13A,FGFR3,BAIAP2,TRMO,RASL10A,ZNF276,DIDO1,BTN2A1,NXPH3,ADAM22,NOVA1,PRKAR1B,QRICH1,RET,REV3L,ZFHX4,SH3BP2,SH3GL3,SLA,ZBTB43,CLSTN2,GPR161,TNS1,TP53BP1,SLC17A7" Drug 2876_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASIC1,ADORA2A,APAF1,PLA2G4C,CFLAR,GYG2,GSDME,TMCC2,SHANK1,SNX29,TENM1,C3orf18,HSD17B14,F5,AFF2,KHDRBS3,POLL,RASSF8,HLF,MYO7A,NNAT,PPARA,MINDY2,CEP41,PRKAR1B,PRKCB,MASP1,PTN,EMID1,DGLUCY,SATB1,SCN8A,ST6GAL1,ARHGEF40,PARD3,FAM155A,DPF3" Drug 4785_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APBA2,ARNTL,CFAP410,SYNGR3,SEPT7,CNTFR,GIT2,SPOCK3,MTSS1L,PIPOX,KAT8,FYB1,SRCAP,GPD2,GPER1,ADAMTS13,GRM2,ICA1,ITGA7,KCNQ3,KHK,MPP2,SLC11A2,LRRN3,FAM184A,FRMPD1,CPEB3,ST6GAL1,FAM214B,PKNOX2,ST5,GPR161,TK2,BEX4,FLRT2,REEP1,KCNAB1" Drug 5028_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADORA2A,AGT,MARK4,RASL11B,ST3GAL5,GYG2,CRLF1,PLAA,CNTN1,AKAP7,RCHY1,DCAF4,RUSC2,RCAN1,HIPK3,MBNL2,ERCC2,FGFR1,ALDH1L1,GLYR1,POLL,GNG4,PRUNE2,KCNH2,KHK,KIT,PDE4D,MINDY2,MAPK10,CARF,PKNOX2,SLC11A1,COA1,TRIO,LMF1,KCNAB1,EPM2A" Drug 3238_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG2,NME5,C1QTNF3,ALCAM,BIN1,APBB2,APC,GYG2,CA4,SLC16A4,CHRNA4,AKAP7,BAG4,NECTIN3,VCAN,SPEG,FGFR1,ERAP1,GATM,ATXN2L,ITGA7,LIFR,CNOT4,MTRF1L,MAPK7,SH3BP2,ASAP3,ANKRD6,SLC6A8,ARHGAP26,CDK19,JMJD6,OBSL1,TEK,ICAM5,TNS1,SMIM8" Drug 4826_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADRA1D,AK2,LTBP4,PKP4,APOC1,RIPK1,ADAM15,AP4M1,FAM189A2,DCAF8,ZNF337,DCTN1,B3GAT3,SUGP2,PRRC2B,BTN2A1,MAP4K5,HNMT,MAP4,MBD1,PLEC,MBOAT7,PTK2,ZDHHC14,RGS3,ATXN2,SH3BP2,ELMO2,SMARCA4,PHLDB1,TRIM2,CBX5,UBTF,PLPPR2,VGF,XRCC4,NDRG4" Drug 4130_DN Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG2,AMH,AMPH,APC,ARHGDIG,PDE8B,KIF1A,CFAP410,CA4,RUNX1T1,STOML1,NRG2,CPS1,ARHGEF10,RUSC2,HS3ST2,DUSP9,EDNRA,ING4,ZNF589,FGFR1,FHL1,GAD1,USP19,RAB30,GRIK5,HLF,TJAP1,MYO7A,LRP12,TCP11L1,ZNF821,IQSEC2,PLCB1,SMG6,PCDHGB6,TNS2" Drug 3353_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AK2,LTBP4,DOC2A,AMPD3,APLP1,MARK4,SLC2A11,CFLAR,FUBP1,CLGN,ARHGEF4,PPP6R2,MAML1,ARMCX2,MED12,RCAN1,SUGP2,ING4,CDKL3,STRADA,SEPT9,RAB30,KCNN2,MPP2,MAPK7,TCP11L1,RPS6KA2,PKNOX2,KIF13A,MCF2L,SMG6,DICER1,TK2,PLPPR2,KLC2,XRCC4,ZNF45" Drug 4465_DN "estradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AMPD3,CDC42BPA,BCAS1,PRX,PPP4R4,CDK13,DNAH17,BMP7,SCAPER,BAIAP3,CLTB,SULT4A1,PICK1,CRMP1,DMPK,HPCAL4,EFCAB2,KCNMB4,GNAL,GRIK5,KCNJ5,KCNN1,LAMA2,LYRM9,NF1,NTRK2,PLCB2,MAPK7,ZSCAN32,SLA,SLC9A5,SPTB,DDN,TBCEL,THRA,TRIO,SPHK2" Drug 5277_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AQP6,MARK4,CACNA1I,RUNX1T1,TPP1,FAM189A2,CNTN1,SNPH,C2CD2L,EDN3,TNK2,RASGRP2,IGSF6,PTK2B,OLFM1,FHL1,FAM49B,FYN,DISC1,RUNDC3A,IL6R,IL12A,MSR1,NCF2,CLDN11,TREM2,PCDH9,SBF1,SLC14A1,SPTB,IQSEC2,PCDHGB6,CHST5,UBE3A,VGF,LAT2,EVI5" Drug 3076_DN Aminohippuric acid [61-78-9]; Down 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ACTN1,MTUS1,AMPD2,APC,BCL7A,LDLRAD4,ARHGEF1,AP4M1,SOCS6,CLTB,HOMER3,PDE4DIP,PPP1R16B,ZNF337,TM9SF4,ING4,STX2,IQCG,CINP,LILRA2,MAP4K5,AGBL5,ZNF862,GPR85,FAM184A,KDM4B,ZSWIM8,CDK19,RBM26,TCF4,SSBP2,WIPF1,LAT2,ZNF24,ATP6V0E2,CIAPIN1,PARP11" Drug 5757_UP Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADD2,ADORA2A,AP2A2,CDK10,RAB26,NCOR2,C2CD2L,DTNA,FEM1B,RCAN2,ZNF549,DCTN2,ERAP1,RAB30,PRUNE2,STMN2,ATXN2L,KCNN2,LAMA2,AFF1,PDE4A,CNNM2,ZSCAN32,ZMAT4,NEK11,SUPT20H,PPM1E,DZIP1,SLC6A11,LHPP,COBL,TACR1,PHF24,PCDHA6,TPM1,TUBB1,VAV1" Drug 1010_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABR,ABHD6,AK2,ATP6V0A1,CFLAR,B4GALT6,LHX2,EPS15L1,DBT,FCF1,OLFM1,CINP,GHR,FERMT2,MUM1,KHK,MMP16,GIT1,NEK1,NFYA,SLC11A2,OGG1,PLXNB1,LRP12,ZCWPW1,FAM192A,ZFP30,EPN2,CLASP2,NXT2,SYT1,PLPPR2,ZBTB14,ZNF45,NDRG4,CIAPIN1,PHTF2" Drug 5011_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "KIAA1324,C1QTNF1,SPARCL1,BIN1,APBA2,CHRD,GYG2,CAMK2B,CNTN1,NCOR2,SPOCK3,HIPK3,MBNL2,STX2,ERCC2,CORO2B,DLC1,OLFM1,FGFR3,ERAP1,SPACA9,KCNH2,NF1,NKAIN1,ZNF493,SBF1,ASAP3,PKNOX2,LIMCH1,HECW1,CDK19,ST5,PLCB1,VIPR2,EVI5,PLSCR4,DPF3" Drug 4089_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ARSE,PDE8B,N4BP2L1,CAMK2B,NRXN3,AKAP6,ABCG1,CSF1R,SPOCK2,C2CD2L,EXOG,DRP2,RASGRP2,IGSF6,AGAP2,DISC1,GNAO1,TPPP,GRM8,PADI2,KCNJ5,MAN2A2,AFDN,ADAM22,NF1,NTRK2,PFKFB4,C19orf57,MAPK10,SEMA6D,ZNF334,RBM26,DDN,ATP10B,SYT5,KCNK12,KCNAB1" Drug 4997_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NME5,SRPX,PPFIA3,ADAM15,CFLAR,PLEKHB1,DOCK4,GIT2,MFAP3L,DNM1,ING4,USPL1,ANKMY1,ZNF589,FER,BAIAP2,PDLIM5,DISC1,GPD2,RASSF8,INPP5B,ZNF862,SLC25A23,APTX,CCDC25,ZNF821,BTBD7,KDM4C,ANKRD28,EXOC7,IQCE,CRTC1,TRPS1,PLPPR2,KLC2,REEP1,GDPD5" Drug 3204_DN Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APC,FAM131A,CDK10,KIF1A,SCAPER,CAMK2G,USP2,QKI,HOMER3,WHRN,SH2B1,DBT,DTNA,EDNRA,COQ7,STX2,INPP5K,AGFG1,KHK,KITLG,MMP16,ADAM22,NF1,SLC25A23,APTX,ELOVL2,RGS12,RNASEL,NLGN1,EXOC7,ZNF34,TK2,NPL,HIRA,VGF,VIPR2,UBE3B" Drug 5301_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NME5,OGT,KCNAB2,APOC1,PPFIA3,ARNTL,STX16,ATP6V0A1,ARHGAP33,EPS15L1,VAX2,DCAF8,ZNF337,GIT2,JAKMIP2,FCF1,EPB41L2,EFCAB2,TXNL4A,GLYR1,BTN2A1,KHK,ADAM22,NFYA,LRP12,RAD51D,RGS12,SYBU,ZNF430,RCOR3,CLASP2,ARHGEF9,TBL1X,SATB2,TPM1,METTL3,ZNF24" Drug 3093_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "MTUS1,PKP4,BCL7A,CFLAR,LDLRAD4,SLC16A4,ARHGEF1,CLGN,B4GALT6,PLAA,CSF1,HIPK3,MBNL2,EZH1,FECH,PDLIM5,OGA,PRRC2B,DIDO1,MKLN1,ZNF862,NF1,NFYA,SNRK,PTPRO,CCDC25,SEC14L1,FBXO11,SLC2A5,SMARCC2,DBNDD2,CDK19,RGL1,TCF4,NPL,PARP11,PHTF2" Drug 1841_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AK2,APC,CAPN3,RCBTB2,CNOT8,HOMER3,VCAN,GAPVD1,MED12,FRY,SUGP2,FKTN,IP6K2,CINP,ARFIP1,DIDO1,HSF2,MARK3,MIA2,SETD4,SNX10,LRP12,PPP5C,C1orf109,ZNF331,SH3BP2,DZIP1,GLT8D1,SPTAN1,ZNF302,LARP4,SS18,VPS13A,SIK3,TMPO,UBTF,FIP1L1" Drug 590_UP 3-aminobenzamide; Up 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADD2,NCOA1,BAIAP3,HIP1R,CBFA2T2,TBRG4,TAOK2,CNTFR,ENTPD4,TBC1D5,EGR3,RGS17,EIF1,ENO2,FGFR1,FGFR3,BAIAP2,TRMO,ALDH1L1,IRF8,MAPT,MBP,NELL2,NPR2,OCRL,LRRN3,MAPK3,PRPH,KCTD17,ZNF821,AMBRA1,EPN2,FAM214B,CDK5RAP2,IQCE,ZMAT3,KCNAB1" Drug 3724_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AMT,APOC1,ADGRB2,ARHGEF2,SOCS6,CHN2,B4GALT6,CRY2,NCOR2,ARMCX2,PARD6A,DMPK,TUBD1,FGF1,FGFR1,KCNMB4,TDRKH,CACFD1,CNOT4,SERPINI1,RETREG1,MAPK7,CNNM2,SAMD9,SUSD4,GAL3ST4,TSNAXIP1,SPTAN1,DDN,SS18,TNS2,TIAM1,TMPO,CABIN1,TNS1,VGF,GAN" Drug 7455_DN Panthenol (D) [81-13-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AP2A2,MTUS1,AK2,APAF1,MARK4,ATP2A2,MTMR2,SCARB1,TAOK2,DZIP3,DCAF8,ZFYVE16,ZNF337,KIAA0586,GIT2,LYPD1,FEM1B,APH1A,EIF5,CINP,GPD2,AGBL5,LSS,NF1,OGG1,OXTR,GTDC1,ROBO1,FERMT1,FNDC3A,KDM4B,SPART,TACC1,MCF2L,EXOC7,HIRA,NDRG4" Drug 7345_UP Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADORA2A,NME5,MTMR3,BAIAP3,CAMK2G,RAB33A,CRY2,NCOR2,PDE4DIP,ARHGEF4,SEC14L5,HDAC9,DENND4A,FER,CAMKK2,SIGLEC8,POLL,LPAR4,GRIK5,GRM8,ATXN2L,INPP5B,GIT1,NF1,CNOT4,NTRK2,PDE4B,PRPH,ZSCAN32,RIPOR1,ATP10B,PHLDB1,WSCD1,BHLHB9,ZKSCAN5,MAP3K12,HPS4" Drug 2529_UP Nadide [53-84-9]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABHD6,BIN1,APAF1,BMP7,CACNA2D1,CD86,B4GALT6,SIPA1L1,DZIP3,ZFYVE16,SV2B,ENO2,EPB41,ERBB2,AGAP2,NEU3,GCNT2,GFER,GPD2,AP4S1,LSS,PDE4A,DUSP26,CCSER2,PPP5C,RTN1,SEC14L1,SH3BP2,EPN2,TMCC1,SPTAN1,SPART,KIAA1107,TBCEL,TRO,KLC2,SENP7" Drug 6676_UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "RALGAPA1,ADCY6,APOC1,ATP2B2,ATP6V0A1,RGS11,CFLAR,SYNJ1,CFAP410,HAP1,CAMK2B,CBS,CD86,SCARB1,EPS15L1,CSF1,PPP1R16B,C2CD2L,ING4,EPHB1,FAM198B,FDFT1,GATM,GSN,CDH20,KCNJ5,MAP4,TM6SF1,AFF1,NPY,RASGRF1,ZMAT4,RGS12,SLC11A1,SPTB,LAT2,KCNAB1" Drug 4250_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "TRMT9B,ADGRB2,KSR1,BAIAP3,CACNA2D2,TAOK2,WHRN,CSF1R,ARHGEF10,CNNM1,MTSS1L,ST3GAL6,EFCAB2,SEPT9,RUNDC3A,GPR75,POLL,LPAR4,KCNN1,LSS,AFF1,NOVA2,SLC11A2,PLXNB1,PRKAR1B,PRPH,PTPRB,RGS4,FRMPD1,TSNAXIP1,SZT2,TNS2,TPM2,OSBP2,LMF1,SPHK2,TIGD6" Drug 4114_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "SEMA6A,CDK13,KSR1,BAIAP3,CAMK2B,SULT4A1,WHRN,DAPK3,DMD,EDIL3,MTSS1L,ATXN2L,HMGCR,ICA1,KCNN1,LSS,AFDN,NF1,TREM2,PALM,RETREG1,PLCD1,SLC25A23,GDPD2,C1orf54,SCN8A,SUPT20H,SH3BP2,ASAP3,CNKSR2,SNCA,KIF13A,ZNF415,JMJD6,ICAM5,SLC17A7,AP3B2" Drug 1494_DN Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "PKP4,FAM131A,PPFIA3,ARRB1,CFLAR,SPAG9,DBT,HIPK3,CNNM1,SCML2,COPS8,HTATSF1,GNG4,HSF2,MIA2,SETD4,PIK3R1,CCSER2,STRN3,LRP12,MAPK3,VPS13C,C1orf109,MAP6D1,FNDC3A,EPN2,BTBD7,RCOR3,MAPKBP1,ZNF302,TBL1X,ZNF34,HIRA,ZBTB14,ZNF23,ZNF184,PHTF2" Drug 2851_DN Colistin sulfate [1264-72-8]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "OSBPL1A,SEMA6A,FAM131A,MARK4,NUMB,SCAPER,C5,CSNK1E,JAKMIP2,DNM1,FAM198B,FGFR1,FAM49B,GALC,GLYR1,GPER1,HNMT,KIF2A,MAP4,NFYA,SLC11A2,SETD4,PMP22,C1orf109,ZDHHC14,TRAPPC13,FNDC3A,RBM34,ST5,TACC1,EXOC7,TNS2,PARD3,CABIN1,ZKSCAN5,PLPPR2,ZNF45" Drug 4752_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AK2,LTBP4,BIN1,GAS7,MARK4,GYG2,CBFA2T2,ARHGAP33,CLGN,FOXN3,COL4A5,CTH,STX2,NCALD,ZNF589,IQCG,INPP5K,SRCAP,ZNF276,GLYR1,MEF2C,KITLG,MID1,ADAM22,MYT1,PPP5C,FBXW7,FBXO11,SMARCD3,KIF13A,SPTAN1,DMXL2,CRTC1,PCDHA5,TMEM121,CABIN1,REEP1" Drug 7491_DN CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APAF1,ARRB1,SYNJ2,CAMK2B,CHRNA4,IQCK,VCAN,BRINP1,DTNA,MBNL2,TENM1,FGFR1,SCARA3,GALC,ZNF276,ICA1,SHISAL1,TJAP1,IL6ST,KCNN1,GIT1,PALM,PTN,SH3TC2,SH3BP2,MYH15,SP4,SPTB,ASTN2,CRTC1,NT5M,HPS4,PCBP4,EPM2A,HRASLS,PHTF2,ACTR3B" Drug 5409_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APC,DNAH17,MARK4,HOMER3,NECTIN3,SH2B1,CRY2,DAPK3,DTNA,CNNM1,CELSR3,IGSF6,DLC1,ZNF589,FGFR1,SEPT9,GCNT2,AHDC1,RUNDC3A,SPACA9,IL6ST,KCNH2,LSS,MPP2,ZNF862,NF1,PPP2R2B,SAMD9,RPS6KA2,ZNF821,FAM214B,CCDC88A,BTBD7,DOP1A,NSFL1C,TK2,KAT6A" Drug 3778_DN Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADCY6,ADD2,APOC1,NRP2,PLEKHB1,IQCK,WHRN,CREM,CNTNAP2,DCAF4,GPRASP1,ETV1,IQCG,ANKFY1,DCTN2,TRMO,MSL3,BACH2,HSF2,LIFR,LRP12,GRAMD1C,SAMD9,WDR25,NEK11,FBXW7,ZNF671,ATXN7,NLGN1,ARHGEF40,ZHX3,COBL,SYNE1,GPR161,WIPF1,ZBTB14,RNF146" Drug 4564_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASPHD1,SYN3,ADORA2A,AGT,ADGRF5,LTBP4,FAM135A,APC,RUNX1T1,NCOR2,ABCG1,SUSD5,CNTNAP2,DAPK3,BRINP1,DRP2,SRPK3,PIPOX,CORO2B,ST3GAL6,IRF8,IL12A,MAPT,NELL2,NOVA2,PCDHGC3,PDE4B,RETREG1,RGS12,KIF13A,DDN,KLHL4,TK2,SPHK2,NAV3,FAM13C,GAN" Drug 3083_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "TRMT9B,MPDZ,CACNA1I,RAB33A,RAB26,ABI3BP,MYRIP,ABCG1,USP6NL,DAPK3,SPOCK2,MTSS1L,ETV1,HPGDS,PRUNE2,PCLO,ELOVL5,MAP4,MEF2C,MID1,PDE1B,POU6F1,PRPH,BCAS3,RIPOR1,EMID1,CNKSR2,SEPT8,TACR1,WSCD1,SZT2,OBSL1,SLC35G2,TRO,LMF1,MAP3K12,FZD3" Drug 5728_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AP2A2,AK2,AMT,APC,APOC1,PPP4R4,SULT4A1,CRY2,EIF4G2,ING4,ANKMY1,OGA,SRCAP,ZNF276,GLI2,TDRKH,KCNH2,MAPT,NDP,NF1,CLDN11,PDE4A,NLE1,MAPK7,GAL3ST4,KCTD17,MAP6D1,ZNF331,SH3BGR,FBXO11,ARHGAP26,DDN,THSD1,TNS2,ZNF45,MAP3K12,DPF3" Drug 2282_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADRA1B,TRMT9B,AMPD3,GAS7,ATP2B2,SYNJ2,CFAP410,USP2,CBARP,TAOK2,RAB33A,CLTB,RIMS2,SNPH,DMD,DLC1,SCARA3,FLNC,SEPT9,GPER1,GRM8,ITGA7,PDE4D,GPR85,MASP1,RASGRF1,SLC25A36,ZFHX4,PKNOX2,SLC11A1,SPP1,EXOC7,WSCD1,DMXL2,TNS1,UGT8,FLRT2" Drug 1054_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG3,MAP4K3,MTMR3,MTMR2,HIP1R,LHX2,HOMER3,APPL1,DCAF8,ZNF337,DBT,MFAP3L,RHOBTB1,SGSM2,FEM1B,MBNL2,ENO2,MYO9A,TMEM231,ROBO1,PCMTD2,PPP4R3A,BTBD3,KBTBD4,TMCC1,USP33,ZBTB43,DIP2A,COBL,PARD3,TRIO,UBE3A,XRCC4,MFF,FIP1L1,PHTF2,ACTR3B" Drug 5018_DN Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABHD6,C1QTNF3,BIN1,CDC42BPA,EP400,KSR1,GYG2,SLIT2,STOML1,AKAP7,ARHGEF10,PPP6R2,DCAF8,RASSF2,GIT2,PARD6A,DLC1,FGFR1,FGFR3,TMEM164,IQCG,GLYR1,POLL,STON1,FAM69A,KCNN2,MAN2A2,ZNF862,PDE1C,PLEC,NKAIN1,CEP97,FAM184A,RGS12,KIF13A,FAM155A,MPPE1" Drug 3534_DN Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "CDC42BPA,CFLAR,SYNJ2,SOCS6,SULT4A1,AKAP7,BAG4,CSF1,PDE4DIP,GREB1,RUSC2,MBNL2,VPS13B,COQ7,POLR1B,FLNC,TDRKH,GRIK5,MITF,MPP2,NF1,NPTX1,PALM,PIK3R1,RETREG1,PRKAR1B,PRODH,MAP6D1,SEMA6D,SBF1,RBM34,SPART,MCF2L,TRIM2,TMEM121,RUNDC3B,REEP1" Drug 493_UP radicicol; Up 200; 0.1uM; SKMEL5; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABHD6,NDRG2,PPFIA3,ARNTL,ZSCAN18,VCAN,KLHL3,ING4,DCTN2,PDLIM5,ATP2C1,LILRA2,ADAMTS13,CACFD1,ITGA7,AFF1,NFYA,NPR2,PALM,NUDT11,RNASEL,GSTCD,TCP11L1,HSPA4L,FBXO11,SMARCC2,MAPKBP1,SPART,LMO3,SS18,EXOC7,CBX5,TST,ZNF32,SPHK2,HPS4,LAS1L" Drug 7312_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APOC1,PPFIA3,BID,CAMK2G,KYAT1,BAG4,NRG2,ENTPD4,HINFP,DZIP3,GPRASP1,DBT,KLHL3,AASS,KAT8,FGFR1,ANKFY1,TXNL4A,HMGCR,MBD1,NF1,SLC11A2,OPA1,RAD51D,RGS3,RGS4,MAP6D1,CLIP1,SBF1,AMBRA1,SMARCD3,CAMTA2,ELOVL4,SYNE2,VPS13A,TSN,PHTF2" Drug 4570_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "C1QTNF1,BIN1,APC,CDK13,SLC4A4,ARHGEF7,FOXN3,HOMER3,AATK,DCAF4,SGSM2,EDIL3,CNNM1,FAM13A,CSPG5,MAP4K5,BACH2,DHX35,HSF2,SHISAL1,LIG4,LYRM9,PDE1C,CNNM2,SAMD9,PID1,GAL3ST4,SCN8A,ASAP3,SLC4A3,ZNF334,ARHGEF9,SYT1,DNAH7,PLPPR2,EPM2A,TIGD6" Drug 6396_DN F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASIC1,SEMA6A,SYT13,DOC2A,TRMT9B,APC,PPP4R4,SPTBN4,CDK13,GYG2,CACNA1I,LDLRAD4,RUNX1T1,LY86,PICK1,NCOR2,PHF14,GREB1,RUSC2,MBNL2,TNK2,FUT9,DISC1,PRUNE2,JAK2,MMP16,ADAM22,CNOT4,NTRK3,PLCD1,FAT4,RGS12,STUM,DOK5,DMXL2,TNS2,UBE3A" Drug 1654_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADGRF5,BEGAIN,CDC42BPA,SEMA4G,MARK4,KRIT1,RAB28,PHF14,NR1D2,TSPAN5,PLEKHA1,VPS26C,TRMO,DISC1,MSL3,GPD2,TDRKH,GPER1,MEIS2,ZNF862,NEK1,PDPK1,STRN3,ASAP3,FNDC3A,HECW1,TTBK2,VPS13A,EXOC7,TBCEL,TIAM1,TK2,KAT6B,TRIO,VGF,VLDLR,KAT6A" Drug 6887_UP SB 202190; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG2,BIN1,APOC1,PPFIA3,RIPK1,GYG2,CBFA2T2,CNOT8,WHRN,COL4A5,SLC4A8,BAG4,SPOCK2,LYPD1,EGFR,ZNF589,CGREF1,RUNDC3A,INPP1,KCNH2,MATK,MEF2C,ADAM22,ZNF862,NF1,PPARA,MAPK7,ZSCAN32,RFX2,TCP11L1,ZFP30,KDM4B,TRIM2,CDK20,LMF1,ITM2C,MPPE1" Drug 7173_UP Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AMPH,PDE8B,CFLAR,SCARB1,QKI,AKAP5,CREM,SH2B1,AKAP12,ARHGEF10,PPP6R2,DBT,RCAN1,FCF1,MBNL2,EGR3,TNK2,COQ7,ZNF44,COPS8,POLL,IL6ST,LIG4,MN1,ZNF862,CLDN11,PPP5C,PTPRE,RASA3,SH3BP2,ASAP3,PPP4R3A,ZKSCAN3,PLCB1,ARC,THRA,MAP3K12" Drug 373_DN "estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ACADM,NDRG2,CDK10,BMP7,KCNAB3,DLGAP1,AATK,CSF1R,DZIP3,DAPK1,RCAN1,PHF20L1,ING4,VPS26C,FGFR1,FOLR2,TPK1,HPGDS,GPER1,BTN2A1,KCNJ5,NEK1,NPR2,NPTX1,PDPK1,GPR173,MBOAT7,GAL3ST4,TCP11L1,CLIP1,DOP1A,POGZ,STX1A,TACC1,WIPF1,GDPD5,HPS4" Drug 2774_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "LTBP4,PPFIA3,MARK4,ST3GAL5,SGCE,RCBTB2,HOMER3,NECTIN3,NCOR2,PARD6A,TMCC2,CDON,EGFR,PLXNC1,HSD17B14,GCNT2,LILRA2,GPER1,HLF,TJAP1,IL6ST,KCNN1,MID1,MX1,SNRK,ZDHHC14,RPS6KA2,ARHGEF40,CXXC4,PHLDB1,SYN2,SLC35G2,TRO,HIRA,LAT2,EMSY,EPM2A" Drug 3314_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "KIAA1324,LTBP4,CDC14B,CACNA1G,USP2,CBFA2T2,STOML1,WHRN,CSF1,JAKMIP2,DMPK,STX2,BAIAP2,SRCAP,USP19,ATXN2L,ICA1,IL6ST,ITGAM,MAP4,TAGLN3,MYT1,NTRK2,NECAB2,RGS12,KCNIP1,FRMPD1,LIMCH1,TSNAXIP1,HECW1,ST5,ARC,WSCD1,PCDHGA10,FLRT2,SLC30A3,DNALI1" Drug 3533_DN Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "AK2,PPFIA3,ARRB1,MARK4,CAMK2G,SOCS6,PLAA,QKI,BAG4,ABCG1,CSF1,PDE4DIP,DCTN1,RUSC2,TSPAN5,ERBB2,MAN1B1,HSF2,MATK,MPP2,GIT1,NF1,RGS3,CCDC25,BTBD7,UNC5B,DIP2A,STX1A,ARHGEF9,ASTN2,IQCE,SATB2,ZKSCAN5,ZBTB14,MAP3K12,EVI5,RNF170" Drug 4494_DN Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NME5,C1QTNF1,SEMA4G,MARK4,SCAPER,ARHGEF1,LY86,WHRN,HAPLN1,AATK,VCAN,PPP6R2,DAPK3,DTNA,FGFR1,CINP,DENND2A,ZNF276,GUCY1B1,INPP5B,KPNA5,MAPT,NDP,SAMD9,GAL3ST4,PPP4R3A,ELMO2,COA1,OGDHL,KDM4B,ARHGAP26,ELOVL4,JMJD6,ZEB1,ZNF24,UPF3A,SEMA3B" Drug 1181_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ABHD6,MTUS1,BIN1,APBB2,ST3GAL5,SLITRK5,DZIP3,DOCK4,GPRASP1,CDON,TNK2,RRAGB,FHL1,ANKFY1,PDLIM5,RAB40B,GNAL,GPD2,MAP4,ZNF862,SLC11A2,STRN3,LRP12,RPS6KA2,GALNT10,ANKRD6,ADGRL3,ZEB1,DOCK9,TNS2,PARD3,SSBP2,FAM155A,REEP1,KCNAB1,PCBP4,FAM13C" Drug 1697_UP Triamterene [396-01-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APC,APLP1,PLA2G4C,SLC4A4,SLC2A11,ATP6V0A1,SYNJ2,CDH2,TAOK2,SLC4A8,GPRASP1,HSD17B14,GNG4,GPD1,GPR37,ATXN2L,HNMT,TJAP1,MAN2A2,ZNF862,NFYA,NTRK2,PCDH9,PURG,MBOAT7,POLG,PRKAR1B,MAPK7,SH3BP2,PREX2,USP33,ARHGAP26,SPART,TROVE2,VIPR2,NDRG4,REEP1" Drug 4123_UP Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APAF1,ARRB1,SYNJ1,RUNX1T1,ARHGEF1,WHRN,CRY2,CNTNAP2,DAPK3,SPOCK2,FCF1,EPHB1,SOX21,MSI1,CNOT4,CLDN11,PCDH9,PRKAR1B,CCDC40,ENOX1,NUDT11,GSTCD,STUM,SMARCD3,LIMCH1,DOP1A,NMNAT2,HECW1,EXOC7,KIAA1107,TBCEL,DMXL2,OBSL1,SLC35G2,PIK3R5,PRDM10,SLC17A7" Drug 3284_DN Hydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "DOC2A,KCNAB2,APBB2,APOC1,CFLAR,BMP7,ARHGEF2,CLGN,CACNA2D2,QKI,ENTPD4,SH2B1,CTH,DAPK3,RCAN1,FGFR1,FAM49B,PRELID3A,ERAP1,COPS8,HNMT,INPP5B,KCNH2,MAP4,NF1,SLC11A2,OGG1,SPTAN1,VPS13A,KIAA0930,BEX4,TSN,RPRM,VGF,SEMA3B,MPPE1,ST7" Drug 3016_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APC,ADGRB3,BMP7,CFAP410,RUNX1T1,RAB26,HOMER3,CSF1,SUSD5,CNTNAP2,SPOCK2,RUSC2,KLHL3,SV2B,HS3ST2,DRP2,SRPK3,REEP2,RASSF8,MBNL1,P2RY13,PCSK5,PPP2R2B,BCAS3,PTH1R,RASGRF1,EMID1,SLC11A1,SOX15,NFASC,TACR1,TRIM2,PHF24,DNAH7,SSBP2,KLC2,GAN" Drug 506_DN wortmannin; Down 200; 0.01uM; SKMEL5; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "CDC42BPA,ARNTL,CAMK2G,SLC25A14,WHRN,COL9A3,CDC42BPB,FEM1B,SUGP2,FAM198B,PCYOX1,TRMO,KHDRBS3,FYB1,GNAL,KCNJ5,MEF2C,ADAM22,NFYA,NLE1,PLEC,AP1AR,ATXN2,SH3BP2,CHD9,ELMO2,SMARCD3,MAPKBP1,HECW1,EXOC7,CHST8,TMPO,NPDC1,ZNF184,EVI5,MPPE1,AAAS" Drug 6813_DN 6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "RALGAPA1,ALCAM,CDC42BPA,CFLAR,SYNJ2,SCAPER,GYG2,TPP1,ENTPD4,SH2B1,CRY2,FAM169A,RIMS2,DCAF8,EXOG,ING4,FHL1,GLYR1,IL6ST,KCNH2,MAP4,TM6SF1,PCBP3,STRN3,APTX,RGS12,SLC25A36,CCDC25,RPS6KA2,SEC14L1,ANKRD6,SLC9A5,MAPKBP1,CAMTA2,EXOC7,FIP1L1,ST7" Drug 1989_DN Antipyrine [60-80-0]; Down 200; 21.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG3,NDRG2,EP400,NCOA1,CFLAR,TMEM184B,CSNK1E,PUM1,ZNF337,RCAN1,DCTN4,PDLIM5,FAM49B,CELF1,OGA,LILRA2,GRB10,MAP4,MBD1,MITF,PIK3R1,PRPSAP2,NEK11,ATXN2,TRA2B,SIRT2,ELMO2,SMARCA4,MAPKBP1,ERC1,SS18,TSN,UBE2H,CLDND1,AAAS,FXR1,RNF146" Drug 3085_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG2,MTUS1,BIN1,APC,ARNTL,CBR1,BAG4,VCAN,ZNF337,SPATA2,DTNA,STX2,CAMKK2,CELF1,TRAF3IP2,ERAP1,DISC1,LPAR4,PCLO,AGBL5,KPNA5,MAP4,NFYA,NRCAM,OPA1,PPP3CC,RPS6KA2,RXRA,AMBRA1,ARFGAP1,CDK19,CABIN1,HIRA,NPDC1,UBE3B,PHTF2,NLRP3" Drug 4439_DN prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASPHD1,NME5,C1QTNF3,LTBP4,ALK,APBB2,APC,PPP4R4,MTMR3,BAIAP3,CHN2,TAOK2,LHX2,STOML1,COL9A3,OSBPL3,SLITRK5,FEM1B,MBNL2,PLXNC1,SCML2,KIF2A,KITLG,MX1,LYRM9,PLCB2,CNTLN,RGS12,KIRREL1,OGDHL,IQSEC2,CEP68,TMPO,TNS1,VAV1,XRCC4,ZNF24" Drug 4120_DN Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG2,AMT,APBA2,ARHGEF7,SCAPER,PLAA,HOMER3,AKAP12,IRAK4,ZNF589,FGF13,GALC,GLYR1,PCLO,INPP5B,MATK,KITLG,ADAM22,ZNF862,NEK1,NF1,NFYA,RETREG1,STRN3,PTN,FAM184A,RGS12,SEMA6D,CPEB3,ABLIM3,PPP4R3A,FAM214B,BTBD7,SNCA,SS18,AP4E1,VIPR2" Drug 5871_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ALK,PPP4R4,EPS15L1,NRXN3,RAB26,AKAP6,CSF1R,CSNK1E,BRINP1,MFAP3L,SPOCK3,AASS,ST3GAL6,FYB1,SEPT9,GPD2,CACFD1,GRM8,SCIN,KCNN1,MATN3,AFDN,NOVA2,MAPK7,CNTLN,TMEM231,CCDC40,DZIP1,DOK5,SPP1,DICER1,TRIO,RUNDC3B,UGT8,ZNF74,REEP1,KCNAB1" Drug 2922_DN Epitiostanol [2363-58-8]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "NDRG3,AMT,PPFIA4,ADAM23,BCL7A,SCAPER,CAPN3,SLC16A4,AKAP7,IQCK,CSF1,OSBPL3,DZIP3,EXOG,FEM1B,OPTN,ZNF589,GALC,SRCAP,USP19,COPS8,PCLO,CACFD1,PADI2,MAP4,SLC11A2,PLPPR3,MYH15,RPGRIP1L,TPM1,TRPS1,SSBP2,XRCC4,ZNF32,ZNF225,MAP3K12,NLRP3" Drug 7224_DN Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASPHD1,PPFIA3,NCOA1,SYNJ2,C5,QKI,CREM,ABCG1,DZIP3,DCTN1,FBXL5,SGSM2,DMPK,EDNRA,EGFR,MBNL2,BAIAP2,ZNF276,HNMT,INPP5B,IPO5,MAP4,OGG1,PDE4A,SMIM7,RIPOR1,NKAIN1,FBXW7,SBF1,KIF16B,MAPKBP1,TMCC1,TROVE2,CAMTA2,VPS13A,VAV1,REEP1" Drug 6782_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "APBB2,APC,BACH1,CFLAR,SYNJ2,FAM189A2,CSNK1E,USP6NL,GIT2,MFAP3L,ANKMY1,F8,BAIAP2,ATP2C1,DISC1,MALT1,TXNL4A,HTATSF1,GPD2,BTN2A1,LYRM9,NF1,NFYA,CNOT4,FA2H,MINDY2,PRODH,TMEM104,PTCH1,ELOVL2,MAP6D1,ZHX3,TROVE2,MCF2L,CDK20,XRCC4,SPHK2" Drug 3125_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADD2,AP2A2,MTUS1,AMPH,ADGRB3,MPDZ,BMP7,COL9A3,CRY2,CSF1,RIMS2,ZNF337,TMCC2,HS3ST2,MAMLD1,SRPK3,ETV1,F5,FGF12,KCNN1,ADAM22,NRCAM,CEP41,KLK6,PTPRN2,MARCH1,CLIP1,GALNT10,FAM102A,ASAP3,PREX2,ADGRL3,CRTC1,TPM1,RPRM,PLSCR4,ADAMTSL3" Drug 6633_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "FAM135A,ALK,APAF1,EPB41L5,GAS7,CDC14B,PROM1,BMP7,LY86,ENTPD4,RIMS2,USP6NL,DMPK,DTNA,ZNF391,SPEG,CACFD1,ATXN2L,LIFR,PALM,PRPH,PTN,KCNIP1,PEX26,ARHGEF40,IZUMO4,HECW1,SPTB,CDK19,CEP68,PHLDB1,PLCB1,COBL,MCF2L,PCDHGA10,OBSL1,TNS1" Drug 4406_UP "Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "SYN3,KIAA1324,BEGAIN,CDK13,ADAM23,CFAP410,RUNX1T1,TPP1,STOML1,PICK1,CNTNAP2,TNK2,PIPOX,FYB1,TMEM8B,NEU3,FAM107A,C2orf72,AFDN,NF1,NNAT,PFKFB2,PLCD1,ENOX1,ZNF493,MRAS,SLA,ARHGEF40,IZUMO4,PEG10,ZNF423,TCF4,HIF3A,TEK,TK2,ADAMTS9,ITM2C" Drug 3580_DN Mephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "C1QTNF3,ALCAM,APBB2,GAS7,PPFIA3,CDK10,NUMB,CFLAR,CAMK2G,SOCS6,ENTPD4,JAKMIP2,MFAP3L,ANKMY1,ACSL4,BAIAP2,NOP56,PDLIM5,USP19,ZNF276,MAP4K5,RASSF8,ADAM22,NEK1,NF1,CCSER2,RETREG1,PLXNB1,FAM184A,EMID1,SLC6A8,EXOC7,KIAA1107,SMG6,CRTC1,CABIN1,CDK20" Drug 7027_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "BACH1,BMP7,ST3GAL5,SCAPER,CAMK2G,KRIT1,WHRN,MFAP3L,RCAN1,DTNA,TOM1,ANKFY1,TPK1,SYT17,ICA1,MEIS2,LYRM9,NF1,CNOT4,ENPP2,PLEC,CNNM2,ZSCAN32,RAD51D,RNASEL,FBXO11,FAM214B,VPS13A,DNMBP,RPGRIP1L,TK2,NPL,VAV1,ZBTB14,ZNF24,ZNF45,ST7" Drug 4392_DN Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASPHD1,CDK13,CACNA1I,CBFA2T2,SPOCK2,DBT,RUSC2,DMPK,SLC12A6,RAB30,CNTRL,SPACA9,HSF2,INPP5B,KCNN1,KPNA5,ADAM22,NF1,NFYA,CNOT4,STRN3,C1orf54,NEK11,FNDC3A,SLC9A5,KDM4B,TSNAXIP1,TROVE2,PLCB1,IQCE,WSCD1,PARD3,HIRA,FLRT2,ZBTB14,EMSY,SEMA3B" Drug 2855_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "MTUS1,NME5,BIN1,APC,PLA2G4C,MARK4,ATP2A2,CFLAR,GYG2,PDE4DIP,GREB1,GPRASP1,RASSF2,ING4,VPS26C,EZH1,FGFR1,FAM49B,PRELID3A,FERMT2,GRIK5,GSN,IL6ST,INPP5B,KHK,MEIS2,MX1,ZNF862,ZNF493,KANSL3,SMARCC2,ZNF423,IQSEC2,DMXL2,TK2,LAT2,REEP1" Drug 5812_DN Isoetharine mesylate salt [7279-75-6]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ADRB2,CASK,ADAM15,CDH2,HOMER3,VCAN,SOCS5,APPL1,PPP6R2,DBT,TMCC2,MED12,DYNC1I1,ERCC2,PRKAG2,FHL1,PDLIM5,FERMT2,CACFD1,IFI16,SMAD1,PDE1C,ZFYVE21,PLCD1,PTX3,GTDC1,SEC14L1,SUPT20H,TRA2B,SH3BP2,RCOR3,UNC5B,SPTAN1,PDLIM2,XRCC4,PHTF2,ACTR3B" Drug 990_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "KYAT1,FOXN3,PICK1,CNTN1,ARHGEF10,PDE4DIP,HIPK3,EGR3,CDKL3,VPS26C,ZNF589,FGF12,FHL1,DISC1,AHDC1,GNG4,TJAP1,KCNH2,KCNN1,MIA2,LYRM9,NPR2,GRAMD1C,SAMD9,RGS12,RNASEL,CARF,RPS20,SH3BP2,FUZ,CXXC4,DOK5,TROVE2,DIP2A,PLCB1,SLC44A1,R3HDM1" Drug 3716_DN Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASIC1,ADGRF5,ARNTL,CDK13,ARHGEF2,PLEKHB1,NCOR2,CSF1,VCAN,SLITRK5,SPOCK3,CHRDL1,RCAN1,DTNA,CELSR3,EIF4G2,ING4,ETV1,FGF1,FGFR1,GNG4,ATXN2L,JAK2,MARK1,NF1,CNOT4,NPR2,GPR85,SAMD9,SUGCT,SNCA,DOK5,PLCB1,VGF,VIPR2,LMF1,UBE3B" Drug 4540_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 1.02E-02 1.15E-01 37 196 "ASPHD1,CDK10,ARRB2,BAIAP3,CAST,RAB28,RUBCN,MFAP3L,PLPPR4,PLXNC1,MRNIP,ETV1,EZH1,FGFR1,SRCAP,MSL3,HLF,SYNPO,MAP4,MMP16,MX1,CNOT4,PIK3R1,CNNM2,RIPOR1,PID1,RPS6KA2,MAPK12,ZFP30,DZIP1,PHLDB1,WSCD1,CRTC1,TIAM1,RUNDC3B,LMF1,PHTF2" Drug CID000452307 A-74702 Stitch 1.31E-03 1.00E+00 1.02E-02 1.15E-01 19 80 "C1QTNF3,BMPR1B,RUNX1T1,PLEKHB1,NCOR1,NCOR2,HDAC9,MED12,BRD8,GPR37,KCNJ5,PACRG,RORB,LRRK2,RXRA,SAFB,SST,SSTR2,THRA" Drug 6439_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.33E-03 1.00E+00 1.04E-02 1.17E-01 34 176 "ADRB2,ARNTL,ST3GAL5,CHN2,CRY2,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,ANKRD46,PTK2B,TAOK3,BAIAP2,FYN,GUCY1B1,KCNH2,PCDH9,SERPINI1,PTPN13,RGS4,RPS6KA2,SH3GL3,KIF16B,WDR47,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,RUNDC3B,SSBP2,EVI5,DPF3" Drug ctd:D000517 alpha-Chlorohydrin CTD 1.34E-03 1.00E+00 1.05E-02 1.18E-01 137 942 "ABR,ACADM,AS3MT,ACTN1,SORCS2,SPARCL1,SEMA6A,ABCD2,LTBP4,AMPD3,AMT,PHYHD1,AQP6,ARNTL,ALDH7A1,ADAM23,BID,ST3GAL5,MYRF,IL33,CALB2,RGN,CD38,CDC25B,CDH2,CDO1,UBE2L6,TPP1,SULT4A1,SUMF2,CPS1,GDA,ABCG1,CRYM,CST3,FAM169A,CTH,GREB1,MATR3,DAPK1,SCRN1,DBT,PITPNC1,C2CD2L,GRIN3A,NR1D2,DOCK2,RCAN1,RASGRP1,SEMA3D,EGFR,AASS,SLC43A2,ERBB4,FAM198B,TUBB3,DCTN2,FOLR2,ST6GALNAC3,GABRB3,GABRG1,GCK,TUBA8,GHR,HPGDS,SPIN1,GLUL,GNAO1,LILRB4,GPD1,GRB10,GSTT2,VSIG4,ACOT7,HP,IGF1,SCIN,IL6R,FAM69A,JAK2,SLC35G1,L1CAM,CAMK2N2,LSS,MAPT,P2RY13,NUCB2,IGSF11,P2RX7,ENPP2,PGAM2,ABCB1,PIK3R1,PKM,PLTP,PSAT1,DRAM2,PRKCB,MAPK4,LAMA1,PTH1R,ELOVL2,PTPRD,PTPRN,NKAIN1,QDPR,ACSS3,PRIMA1,RPS20,SAFB,KIF27,SGK1,ABLIM3,SLC2A5,LIMS2,SLC6A8,SP4,PBLD,RGL1,SEPT3,NSFL1C,PRRC2C,COBL,KLHL4,KIAA0930,SATB2,TRIM2,SYNE1,GPRIN3,NPL,AMACR,TST,KCNT2,SPIRE1,TUBA1A,RSPRY1,AP3B2" Drug CID000002464 NSC89595 Stitch 1.37E-03 1.00E+00 1.07E-02 1.21E-01 15 57 "ATP1A1,ATP1A3,ATP1B3,NCOR1,ERCC2,PTK2B,ITGAM,PIK3C2A,PIK3R1,MAPK3,MAPK4,MAPK7,RNASE1,TIAM1,UBC" Drug 5221_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-03 1.00E+00 1.07E-02 1.21E-01 35 183 "ADRA1D,DNAH17,MARK4,N4BP2L1,AZGP1,BMP7,TAOK2,LRIG1,GREB1,CDON,SLC12A6,EGR3,DLC1,SRCAP,LYVE1,GRIK5,IL6ST,MAP4,AFDN,ZNF862,NOVA2,PILRA,SAMD9,ZSCAN2,SEC14L1,FRMPD1,SPTAN1,TSPYL2,CLSTN2,RGL1,EXOC7,TRIM2,R3HDM1,SEMA3B,TIGD6" Drug ctd:D010656 Phenylephrine CTD 1.39E-03 1.00E+00 1.08E-02 1.22E-01 80 506 "ACADM,ADCY5,GALNT13,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PKP4,CADPS,ATP2A2,BMP7,C5,CA4,CAMK2A,RUNX1T1,CCNT1,CDH2,COX4I1,CREM,VCAN,CTH,DAPK1,RCAN1,E2F5,EDN1,EDNRA,EDNRB,EGFR,CALCRL,ENO2,NCALD,FGF12,FHL1,FLT1,ELOVL5,IGF1,KCND2,KCNH2,STMN1,LIMS1,MEF2C,NPY,PDE4B,PKD1,PKM,PLCD1,EPB41L4B,PPARA,PRKCB,MAPK3,MAPK7,MAPK9,MAPK10,MASP1,REV3L,RGS3,RGS4,S100B,SEMA6D,SGK1,SLC4A3,SLC8A1,SLC12A2,CXXC4,SPP1,ADHFE1,PLCB1,TACR1,TRIM2,ZFPM2,ITGB3BP,THRA,CABIN1,RASD2,TPM2,TSC2,UCHL1,HRASLS" Drug 3458_UP Ebselen [60940-34-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "AMPD3,BIN1,KCNAB2,MARK4,SLC4A4,ATP2B2,CFLAR,ASIC3,ENTPD4,SH2B1,CSF1R,C2CD2L,GSDME,EDNRB,PLXNC1,FECH,ERAP1,MSL3,ELOVL5,KCNJ5,SLC11A2,PFKFB2,PLTP,SAMD9,GTDC1,SH3BGR,ZHX3,UNC5B,DIP2A,CHST8,TRIO,TRPM2,REEP1,SLC30A3,EMSY,EVI5" Drug 2525_DN Strophanthidin [66-28-4]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "MARK4,NCOA1,ST3GAL5,SYNJ2,CAMK2G,EPS15L1,RHOBTB1,MRNIP,F8,ZNF589,GLUL,IFI16,KIF2A,SETD4,PDCD2,RETREG2,PPP5C,PTCH1,ZFP30,ST6GAL1,ARHGEF40,CLASP2,ZNF302,CEP68,KANK1,FAM208A,ATMIN,TK2,TNS1,TPM1,METTL3,TST,UBTF,FLRT2,ZNF32,REEP1" Drug 2866_DN Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "EPB41L5,CDC14B,CDK10,ADAM15,BCL7A,TPP1,HOMER3,DAPK3,DBT,NR1D2,RCAN1,DTNA,HIPK3,FCF1,EIF4G1,SCML2,GALC,SPIN1,GLYR1,GPD2,GSN,AGFG1,LSS,KITLG,NEK1,PIK3R1,PLXNB1,SEC14L1,PEX26,ZBTB43,SS18,ARHGEF9,AP4E1,KLC2,EPM2A,RNF146" Drug 2296_DN Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "AK2,SRPX,CDC42BPA,APOC1,STX16,SYNJ2,SPAG9,QKI,BAG4,DTNA,FCF1,APH1A,ZNF589,ANKFY1,ARFIP1,HSF2,IL6ST,MBNL1,MPP2,NFYA,SETD4,PIK3R1,PLEC,POLG,PEX26,PPP4R3A,FAM214B,ZBTB43,NXT2,SYT1,TRIM2,TMPO,ZNF24,SH3GLB2,EMSY,FXR1" Drug 5080_DN Lobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "MTUS1,NME5,EP400,ALDH7A1,SCAPER,SPAG9,FOXN3,TPP1,CPS1,CNTNAP2,KIAA0753,PARD6A,EDIL3,FAM13A,SPEG,ZNF589,CINP,B4GALNT1,ERAP1,GPER1,INPP5B,CNOT4,PDE4A,PIK3R1,CNNM2,ZSCAN32,RPS6KA2,SBF1,CSRNP3,SCN8A,FBXO11,SMARCD3,LIMCH1,ASTN2,GPR161,TFIP11" Drug 4099_UP Alprostadil [745-65-3]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "BEGAIN,PPP4R4,NRP2,SCAPER,RAB33A,STOML1,CREM,AKAP12,PHF14,CTH,ARHGEF4,SPOCK2,C2CD2L,SPOCK3,EDIL3,GDF9,RUNDC3A,GPD2,CACFD1,SOX21,HAS2,JAK2,KCNQ3,TM6SF1,ADAM22,MX1,NF1,SMOX,RGS4,KCTD17,CSRNP3,ZNF821,SLA,SS18,ARC,PHTF2" Drug 2456_DN Ciclopirox ethanolamine [41621-49-2]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "RALGAPA1,ADRB2,AMT,APOC1,C5,LDLRAD4,CAMK2G,KRIT1,TPP1,STOML1,ARMC8,SLITRK5,ELMO1,SUGP2,ST3GAL6,ALDH1L1,POLL,LILRA2,MAN1B1,IRF8,ITGAM,NINJ2,RETREG2,ZCWPW1,ERI2,HSPA4L,PPM1E,SLA,TROVE2,CEP68,RGL1,METTL3,LAT2,REEP1,LAMP5,HPS4" Drug 5614_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "NDRG2,NME5,APC,ARHGEF2,RCBTB2,NECTIN3,CRY2,PDE4DIP,GIT2,JAKMIP2,TSPAN5,SUGP2,MBNL2,STX2,NCALD,FAM49B,GCNT2,HTATSF1,INPP5B,LSS,TM6SF1,PRKAR1B,PRPH,RGS3,FERMT1,FBXO11,EPN2,KDM4C,TROVE2,ST5,PLCB1,TRIM2,HIRA,FAM155A,ZNF711,SLC17A7" Drug 4114_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "LTBP4,AMPD3,CDC42BPA,PKP4,APC,BCL7A,BMP7,SOCS6,TAOK2,QKI,FAM169A,TBC1D5,GIT2,DTNA,FCF1,EIF4G1,ZNF589,FGFR1,GLYR1,RAB30,MSL3,IL6ST,JAK2,MAPT,MMP16,NEK1,SAMD9,ZCWPW1,TCP11L1,SH3BP2,PPP4R3A,FAM214B,PRRC2C,TBL1X,TMPO,KAT6B" Drug 6253_UP Ellipticine [519-23-3]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "NCOA1,ADAM15,VAX2,QKI,ARHGEF6,CREM,CSF1,PDE4DIP,CDON,MBNL2,TNK2,HSD17B14,BAIAP2,SCARA3,GAD1,B4GALNT1,SPACA9,PADI2,MAP4,NELL2,NF1,NPTX1,PDE4A,RETREG1,PTCH1,C1orf54,SGK1,WDR47,SLC9A5,SNCA,CLSTN2,ARC,EXOC7,TPM1,PLPPR2,TIGD6" Drug 1550_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; HL60; HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "APBA2,MARK4,NRP2,SCAPER,CD86,ARHGAP33,SH2B1,PPP1R16B,FAM13A,PHF20L1,ENO2,IGSF6,ALDH1L1,PCDH17,GNAO1,PRRC2B,IFI16,ITGAM,NCF2,RETREG1,PLCD1,SLC25A23,SAMD9,RGS12,RNASE1,FBXW7,ZNF671,SGK1,SH3BP2,SLC6A8,HECW1,SPP1,SAMSN1,PDLIM2,CLDND1,ACTR3B" Drug 3468_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "RALGAPA1,C1QTNF3,AMT,ARHGDIG,ARRB2,ATP6V0A1,GYG2,ENTPD4,ARHGEF10,ARHGEF4,MAML1,PLEKHA1,FHL1,GLYR1,STON1,ITPKB,KCNF1,LMO2,ADAM22,FSD1,FAM184A,ZDHHC14,GSTCD,ROBO1,PEX26,EPN2,BTBD7,COA1,SMARCD3,KDM4B,SPTAN1,PLCB1,DMXL2,ZNF34,SLC44A1,EMSY" Drug 5602_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 1.09E-02 1.23E-01 36 190 "ACTN1,AGT,APAF1,APBA2,APOC1,GYG2,CFAP410,ABCG1,VCAN,PDE4DIP,CTH,GREB1,RASSF2,MFAP3L,EDNRA,ING4,MTSS1L,AGAP2,GATM,GNAL,STON1,GPR37,GRM8,MAN2A2,MIA2,AFF1,AFDN,NF1,SLC9A5,TSNAXIP1,CDK19,SPART,PHLDB1,TRIM2,BEX4,XRCC4" Drug CID000091773 tebufenozide Stitch 1.42E-03 1.00E+00 1.09E-02 1.23E-01 8 21 "BTK,USP2,NCOR2,IP6K2,DDX19B,PDCD2,RXRA,USP1" Drug 7063_UP MG-262; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 33 170 "BRAP,BIN1,BMP7,ST3GAL5,CAMK2G,CARS,CLGN,CREM,CRY2,ABCG1,CTH,DTNA,DNAJB6,FHL1,PDLIM5,FAM49B,ATP2C1,FYN,FERMT2,GRB10,CACFD1,LMO2,MIA2,PRPH,HSPA4L,SH3BGR,PPP4R3A,UNC5B,TSPYL2,THSD1,TRIM2,REEP1,ZNF195" Drug 7283_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APC,KIF1A,KSR1,CACNB4,RAB28,HAPLN1,CSF1R,AASS,CDKL3,FYB1,ZNF44,GAD1,SEPT9,LPAR4,IRAK3,LSS,MAPT,MGAT3,AFDN,PDE4D,SAMD9,KHDRBS2,RGS3,SCN2B,MRAS,FRMPD1,AMBRA1,KDM4C,TEK,THRA,PIK3R5,TRO,OSBP2,VIPR2,XRCC4,REEP1,KCNAB1" Drug 6320_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,CDC14B,NUMB,ALDH7A1,ADAM15,PDE4DIP,FEM1B,FCGRT,DLL3,OGA,B4GALNT1,MSL3,GPD2,GUCY1A1,RASSF8,IPO5,NFYA,CNOT4,NLE1,MAPK3,MAPK7,PRPH,RXRA,MAPK12,ASAP3,FUZ,NLGN1,KBTBD4,SPATA7,POGZ,SEPT8,ARHGEF9,ASTN2,LMF1,XRCC4,PCBP4,MPPE1" Drug 4408_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BEGAIN,CDC14B,SEMA4G,CDK13,SGCE,CFAP410,CACNA1A,TAOK2,CSF1,CDON,EDN1,FRY,TNK2,PTK2B,NSG1,ERAP1,SIGLEC8,ITGA7,KCNB1,AFDN,ZNF862,NF1,NOVA2,NTRK3,GPR85,PNMA3,CEP41,ZNF821,LIMS2,SLC11A1,SLC12A4,SNCA,SOX15,RGL1,PLCB1,SLC19A3,TUBB1" Drug 5461_DN Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "C1QTNF3,CDC42BPA,DNAH17,CFLAR,BAIAP3,CCNT1,ARHGAP33,MAGI1,SRSF11,PICK1,DAPK3,MFAP3L,RUSC2,VPS13B,F5,FHL1,EFCAB2,GCNT2,TDRKH,GRIK5,AP4S1,KCNF1,MAP4,ADAM22,CNOT4,RETREG1,LRP12,MAPK7,PRODH,ELOVL2,ZDHHC14,GSTCD,ZNF821,CXXC4,RPGRIP1L,SPHK2,SENP7" Drug 5503_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AK2,APC,APOC1,SCAPER,KYAT1,TBRG4,CRLF1,EPS15L1,FAM189A2,IQCK,RASSF2,RUSC2,C2CD2L,STRADA,FHL1,CGREF1,MSL3,POLL,IL6ST,MPP2,NFYA,NTRK2,PDE4B,SLC25A23,SAFB,SBF1,SH3BGR,PREX2,FAM214B,BTBD7,RBM34,SAMSN1,VPS13A,CDK20,PLPPR2,ZNF24,SMIM8" Drug 5675_DN Colchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APBB2,APOC1,PDE8B,CFLAR,SCAPER,CA4,QKI,ARHGEF10,GPRASP1,MFAP3L,RUSC2,CELSR3,ING4,MRNIP,BAIAP2,PRELID3A,TRAF3IP2,TXNL4A,GLYR1,HNMT,MAP4,ZNF862,NF1,CNOT4,FSD1,PPP2R2B,SNRK,ZSCAN32,RAD51D,SBF1,LIMCH1,ZHX3,THSD1,FAM155A,VIPR2,EVI5,TIGD6" Drug 7486_DN CP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASIC1,ADORA2A,AK2,APBB2,PPP4R4,ADGRB1,CLGN,CACNA2D2,SRSF11,ARHGEF6,CNTFR,ARMC8,BAG4,PDE4DIP,MAML1,TMCC2,SLC12A6,EGFR,FGFR1,SEMA4D,PDLIM5,RASSF8,ATXN2L,KIT,NLE1,PLCD1,MAPK7,KDM4B,SOX15,SPTAN1,DMXL2,PCDHA5,TRIO,UCHL1,VIPR2,REEP1,EPM2A" Drug 4982_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ALCAM,SRPX,AMT,NCOA1,MPDZ,CFLAR,SYNGR3,PLEKHB1,LHX2,TPP1,AKAP12,PDE4DIP,ARHGEF4,PPP6R2,RCAN1,DTNA,MAMLD1,VPS26C,KAT8,FHL1,PRELID3A,B4GALNT1,DISC1,POLL,IPO5,MAPT,LYRM9,NEK1,PLCD1,PRODH,TMEM104,ZDHHC14,SH3BP2,SMARCC2,VPS13A,VIPR2,REEP1" Drug 2720_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADD2,BIN1,SEMA7A,CDC14B,DNAH17,ZSCAN18,GYG2,SGCE,MYRF,CACNA2D1,CRY2,TMCC2,TENM1,FGFR3,FOXF2,ALDH1L1,GFER,ICA1,KCND1,KIFC3,KIT,MGAT3,SCAMP5,FXYD1,FA2H,MASP1,PTPRN2,CCDC40,SUSD4,STUM,SYBU,ZHX3,PHLDB1,MCF2L,CHST8,GPR161,FZD3" Drug 7411_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "RALGAPA1,ALCAM,APAF1,ARHGDIG,TPP1,NECTIN3,SEC14L5,C2CD2L,CELSR3,PHF20L1,DENND4A,CDKL3,FGFR1,COPS8,RNFT2,ATXN2L,ELOVL5,MIA2,SCAMP5,MITF,MMP16,NTRK2,MBOAT7,PRPH,ZSCAN32,RIPOR1,FAM184A,RGS12,RNASEL,GSTCD,SBF1,SLC11A1,ZC3H13,WIPF1,TFIP11,GDPD5,HPS4" Drug 2782_DN Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "RALGAPA1,ARHGDIG,BAIAP3,ASIC3,CNOT8,SLIT2,CREM,ENTPD4,CSF1,DAPK3,ARMCX2,JAKMIP2,DTNA,HIPK3,OPTN,ING4,NCALD,SEPT9,ALDH1L1,AHDC1,POLL,GRIK5,ELOVL5,ADAM22,SLC11A2,CNNM2,ZSCAN2,C1orf54,SMARCD3,LIMCH1,ZC3H13,SPART,TMEM121,SLC44A1,KAT6B,CABIN1,MAP3K12" Drug 7038_DN Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BRAP,KCNAB2,EPB41L5,PPFIA3,MTMR2,ARHGEF2,USP6NL,KIAA0586,GIT2,EIF4G2,HSD17B14,ANKMY1,KAT8,INPP5K,TDRKH,RNFT2,DHX35,ADAM22,NCAM2,NEK1,NF1,PDE4A,APTX,RPS6KA2,SLC6A8,ZHX3,UNC5B,STX1A,MCF2L,CHST8,CABIN1,CDK20,METTL3,PLPPR2,VIPR2,ZNF142,TIGD6" Drug 3999_DN Gramine [87-52-5]; Down 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AMPD3,CDK10,SYNJ2,LARGE1,FOXN3,ARHGAP22,WHRN,EDNRA,MRNIP,CINP,TRAF3IP2,B4GALNT1,MSL3,PRRC2B,ITPKA,KHK,TAGLN3,PDE4D,WDR25,KHDRBS2,SBF1,ATXN2,ASAP3,NLGN1,PPP4R3A,SLC9A5,TSNAXIP1,DDN,TIMP4,CABIN1,TNS1,SSBP2,ZKSCAN5,XRCC4,HPS4,SEMA3B,KCNAB1" Drug 5493_DN Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,AK2,PPFIA3,DNAH17,NCOA1,SLC4A4,SCAPER,LHX2,APPL1,DCAF8,ZNF337,EXOG,CNNM1,DLC1,FGFR1,AGBL5,IDH3A,MPP2,NFYA,NLE1,LRP12,PRODH,RAD51D,RXRA,SBF1,SUPT20H,SIRT2,KDM4C,ERC1,PHLDB1,TBL1X,CABIN1,TPM1,REEP1,UPF3A,HPS4,MPPE1" Drug 3122_DN Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BIN1,AMT,ATP6V0A1,ADAM15,MTMR3,TAOK2,CNTN1,IQCK,SIPA1L1,GPRASP1,ZNF337,DGKG,SPOCK2,ING4,TNK2,PTK2B,RAB40B,PCLO,PFKFB4,PLCL1,PLEC,SLC25A23,CNNM2,SBF1,SEC14L1,MYH15,KDM4B,SP2,SPTAN1,CDK19,KANK1,NSFL1C,PCDHGA10,ZNF34,PLPPR2,ZBTB38,PRDM10" Drug 2186_UP Evoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "LGR5,KSR1,BMP7,C5,CAMK2A,ASIC3,STOML1,CREM,CSF1,SIPA1L1,PDE4DIP,SPOCK2,PARD6A,SPOCK3,OPTN,ELN,VPS13B,PRELID3A,CSDC2,RASSF8,MSI1,ADAM22,MYCN,DUSP26,SLC25A23,MAPK7,WDR25,GAL3ST4,FRMPD1,HECW1,ATP10B,TCF4,DOCK9,SLC19A3,SEMA3B,SLC17A7,PLSCR4" Drug 3000_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BIN1,MYRF,CHGB,HOMER3,NRG2,HAPLN1,NCOR2,SUSD5,EXOG,EGFR,EPHB1,INPP5K,NEU3,GPD1,SCIN,KIF5A,MBNL1,MMP16,ADAM22,MYCN,NTRK3,CCDC40,BEND5,GAL3ST4,PNMA8A,DOP1A,PEG10,LHPP,NSFL1C,SMG6,FAM189A1,ZFPM2,TPM2,FLRT2,WNT7A,KLC2,FZD3" Drug 3708_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,ADGRF5,PKP4,APC,CDC14B,MARCH3,CFLAR,SOCS6,ENTPD4,SH2B1,PDE4DIP,SLITRK5,HIPK3,CDKL3,FGFR1,SEMA4D,MARK1,GIT1,ZNF862,CEP41,CNNM2,RGS3,ZNF671,KDM4B,SPTB,IQSEC2,ZBTB43,THSD1,IQCE,TMEM121,GPR161,CABIN1,TRIO,ZNF74,TFIP11,EVI5,KAT6A" Drug 21_UP phenformin hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG3,GAS7,RAB29,CAMK2B,CHN1,AATK,DBT,DCTN1,DNAJB6,OLFM1,BAIAP2,POMT1,AHDC1,ADAMTS13,AGBL5,KCNJ5,KCNN1,L1CAM,MMP17,MYO6,NELL2,NOVA1,CDK18,CCSER2,PLCD1,KLHL11,FAM192A,AMBRA1,PKNOX2,ZC3H13,CLASP2,TBL1X,PARD3,CABIN1,TRIO,PLPPR2,VPS35L" Drug 4181_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,LTBP4,APC,ADGRB3,SYNJ2,AKAP6,ARHGEF10,ARHGAP24,EDN1,MTSS1L,ALDH1L1,SRCAP,GDF9,GNAL,LPAR4,GRIK5,IPO5,AFDN,MYO7A,ZNF862,NPY,OGG1,P2RY1,PCDH8,STRN3,PTPRD,ST6GAL1,PKNOX2,NMNAT2,LMO3,FAM189A1,SLC35G2,TRIO,ZNF711,SLC17A7,PHTF2,JPH3" Drug 2024_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADD1,APOC1,AQP6,ARRB2,N4BP2L1,RAB29,SLC25A14,CAST,CHGB,CHN2,FAM189A2,AKAP7,CREM,MAML1,RASGRP2,KAT8,MALT1,GLUL,GNG4,LILRA2,GPR12,IL6R,MAP4,MYT1,SETD4,PALM,PIK3R1,CCDC25,FAM102A,KBTBD4,ELMO2,IQSEC2,SS18,SYN2,KAT6B,UPF3A,NT5M" Drug 3247_UP Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AMH,APBB2,CDC14B,PPP4R4,CDK13,ATP6V0A1,CA12,CAMK2B,ARHGEF1,ARHGAP33,AKAP7,WHRN,ENTPD4,PPP6R2,DTNA,EGFR,FYB1,GAA,RASSF8,IL6R,MAN2A2,MIA2,MYO7A,PPARA,MINDY2,PRODH,SLC6A8,ARFGAP1,DOP1A,ST5,PHLDB1,STX1A,PLPPR2,VIPR2,SLC30A3,MARCH8,KAT6A" Drug 4186_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "SYN3,AP2A2,DOC2A,APC,GAS7,CDK10,PPP4R4,ZSCAN18,NRP2,CFLAR,SYNJ1,FUBP1,FOXN3,ASIC3,RAB26,SPOCK2,SGSM2,IRAK4,SPEG,PDLIM5,OGA,GALC,ERAP1,DISC1,GPR162,HNMT,KCNB1,LYRM9,PGAM2,PRKAR1B,RET,EMID1,KCNIP1,RASA3,LIMCH1,KIF13A,PDZRN3" Drug 2260_DN Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "RALGAPA1,ASIC1,ADRA1D,AMPD3,BIN1,CDC42BPA,APBB2,GAS7,PLA2G4C,CFLAR,SPAG9,CACNA2D2,FOXN3,GREB1,JAKMIP2,TSPAN5,PLXNC1,FAM49B,GNG4,GPD2,SPACA9,GRIK5,HNMT,IL6ST,MAP4,MAPT,TM6SF1,MYT1,STRN3,PRODH,LIMCH1,PLCB1,CRTC1,TK2,REEP1,SLC30A3,KCNAB1" Drug 5787_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "FAM135A,APAF1,FOXN3,SEC14L5,SPOCK2,SEMA3D,EGR3,PLXNC1,EZH1,SEMA4D,AFF2,GATM,GLYR1,AFF1,NEFH,NPTX2,NTRK2,CNNM2,TMEM104,PTN,PID1,ENOX1,RGS4,KCTD17,SUPT20H,DZIP1,SLC8A1,OGDHL,ZNF415,SPP1,IQSEC2,HIF3A,BHLHB9,TRO,VAV1,SPHK2,KCNAB1" Drug 4093_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APC,SLC4A4,SCAPER,CACNA1G,CACNA2D1,CAMK2B,MTMR7,DGKI,NRXN3,VAX2,PICK1,SEC14L5,KIAA0319,DTNA,EDIL3,ING4,RASGRP2,ARMCX1,LYVE1,GNAL,GNAO1,ELOVL5,PACRG,ADAM22,PRKAR1B,RFX2,SEMA6D,SCN2B,ASAP3,SLA,PKNOX2,ARHGAP26,SSTR1,COBL,TAL1,TRO,RPRM" Drug 1322_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MAP4K3,GAS7,CDK13,N4BP2L1,CFLAR,RAB28,TM9SF4,TBC1D5,GSDME,SUGP2,ERCC2,IGSF6,VPS26C,ICA1,TJAP1,JAK2,LIG4,MEF2C,MINDY2,CEP97,RAD51D,HSPA4L,AMBRA1,FNDC3A,SLC12A2,CDK19,TSPYL2,NXT2,ARHGEF9,EXOC7,SIK3,METTL3,UBE2H,XRCC4,ZNF24,FTSJ1,LAMP5" Drug 3098_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASPHD1,ABHD6,APBB2,RAB33A,CNTN1,CREM,AATK,C2CD2L,HS3ST2,PRELID3A,ELOVL5,HNMT,KCNJ5,KHK,MGAT3,PFKFB4,PLCD1,PURG,PSD,CCDC40,RFX2,ZFHX4,KLHDC8A,MAP6D1,SH3BGR,ST6GAL1,KANSL3,SLC6A11,RBM34,TSNAXIP1,SOX15,ARHGAP26,LHPP,FAM155A,LMF1,SLC30A3,SLC17A7" Drug 1796_DN Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADCY6,BIN1,CDC42BPA,APOC1,ZBTB10,EIF4G3,PTBP2,HOMER3,WHRN,PDE4DIP,DAPK3,RUSC2,KLHL3,TMCC2,SUGP2,COQ7,STAU2,SRCAP,CACFD1,MUM1,SHISAL1,NFYA,PDE1C,CCSER2,FA2H,POLG,BCAS3,TMEM104,ZC3H14,ATXN7,AMBRA1,SMARCD3,TRIM2,LMF1,ZNF32,PLSCR4,ACTR3B" Drug 2113_DN Gemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BIN1,CDK10,MYRF,CNOT8,DBT,EIF5,IRAK4,ING4,COQ7,FHL1,GPER1,SHISAL1,INPP5B,KIF2A,MAP4,SCAMP5,NLE1,ZNF426,CNNM2,SAMD9,NUDT11,SUPT20H,CCDC88A,SMARCC2,CDK5RAP2,SS18,CEP68,COBL,KIAA1107,SATB2,ZEB1,TRIM2,UBE3A,LMF1,XRCC4,MPPE1,PHTF2" Drug 7150_DN "(+,-)-Synephrine [94-07-5]; Down 200; 24uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APBB2,MPDZ,AKAP7,FAM169A,EDIL3,EGFR,EIF5,STX2,ST3GAL6,ZNF589,ANKFY1,EFCAB2,INPP5K,GLUL,IFI16,FAM69A,MKLN1,CNOT4,SETD4,CCSER2,PRKACB,TMEM104,PID1,ROGDI,HSPA4L,SHMT2,ZKSCAN3,DOP1A,TTBK2,KIAA0930,TRIM2,PLPPR2,KLC2,FZD3,PHTF2,ACTR3B,AAAS" Drug 5463_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,AK2,C1QTNF3,PKP4,APBB2,APC,PPFIA3,ST3GAL5,MTMR2,C5,KYAT1,LHX2,PDE4DIP,DTNA,COQ7,NOP56,TRMO,USP21,ACOT7,ITPKB,MITF,SLC25A23,PRKAB2,ROBO1,SBF1,KIF16B,TTC17,TMCC1,RBM34,TROVE2,ELOVL4,PHLDB1,VGF,XRCC4,ZNF74,MAP3K12,RNF146" Drug 3433_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,CFLAR,SCARB1,STOML1,QKI,CREM,CSNK1E,ENO2,DENND4A,ATP2C1,SRCAP,FERMT2,MAN1B1,ADAM22,PRKAR1B,CNNM2,TMEM104,GTDC1,SGK1,FAM102A,FBXO11,RCOR3,CLASP2,CAMTA2,ARHGEF9,VPS13A,TACC1,MTCL1,MCF2L,EXOC7,NSD1,TIAM1,WBP2,HIRA,ZNF45,MPPE1,SMIM8" Drug 5672_DN Tyloxapol [25301-02-4]; Down 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ABHD6,AK2,APBB2,APOC1,ARRB1,PLEKHB1,HOMER3,CDC42BPB,SIPA1L1,PDE4DIP,CTH,GREB1,GIT2,DMPK,DTNA,PRELID3A,AHDC1,GLYR1,RNFT2,MAP4K5,MATK,MBD1,NF1,PRODH,PRPH,RXRA,MAPK12,FBXO11,EPN2,ASTN2,TACC1,PDLIM2,CABIN1,VAV1,ZBTB14,NDRG4,PDSS2" Drug 7500_UP "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,AK2,ALCAM,APLP1,PPFIA3,CFLAR,CAMK2B,CAMK2G,SRSF11,FEM1B,CELSR3,EIF5,ENO2,RASGRP2,BAIAP2,ALDH1L1,MALT1,COPS8,HTATSF1,POLL,ADAMTS13,TJAP1,MGAT3,NEK1,CDK18,KCTD17,SCN8A,SYBU,KDM4B,PEG10,CDK19,STX1A,PCDHA5,TRIO,KCNK12,MAP3K12,PCBP4" Drug 5923_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,AMT,SEMA4G,PRX,ARNTL,CDK13,CACNA1I,LDLRAD4,TAOK2,QKI,CSF1,CSF1R,DAPK3,DMPK,CDON,FGF12,TPK1,FUT9,RAB30,STON1,GPR37,KCNH2,MSI1,NOVA1,PCDH9,PDE4A,LRP12,GAL3ST4,FRMPD1,IZUMO4,UNC5B,PLCB1,SZT2,TK2,TMPO,KCNK12,DNALI1" Drug 7197_DN Isoniazid [54-85-3]; Down 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASPHD1,AP2A2,BIN1,APBA2,BCAS1,PPFIA3,MARCH3,KIF1A,NFS1,ARHGEF1,PICK1,SH2B1,ABCG1,SOCS5,DNM1,MED12,ZNF589,FHL1,MSL3,DHX35,IL6R,KCNF1,MBD1,MID1,MITF,SMIM7,MBOAT7,PPP3CC,PRKAR1B,RIPOR1,ASAP3,SIRT2,ARHGEF9,MTCL1,VGF,HPS4,RNF170" Drug 2135_UP Conessine [546-06-5]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADD2,ADORA1,BIN1,SEMA4G,ADGRB1,CAMK2B,CBFA2T2,CREM,FAM169A,RIMS2,VPS13B,FGF1,BAIAP2,GFER,PCDH17,LILRA2,CACFD1,MMP16,NPY,CEP41,KLK6,CNNM2,PTPRB,SBF1,ZNF821,MRAS,SLC11A1,TMCC1,ZNF423,ZC3H13,SEPT8,CEP68,SYNE2,TRIM2,GPR161,ZKSCAN5,VSNL1" Drug 2974_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,FAM131A,KIF1A,MPDZ,CFAP410,CHRNA4,CNTN1,DZIP3,DBT,ST3GAL6,PDLIM5,KHK,KIT,MGAT3,AFDN,GIT1,PDE4D,NLE1,PLCD1,CEP41,RGS4,RASA3,CPEB3,PREX2,SLC11A1,SNCA,TMCC1,IZUMO4,SPTAN1,SS18,PDLIM2,TCF4,PCDHGA10,SLC44A1,VIPR2,KCNAB1,NLRP3" Drug 3989_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ALDH7A1,SYNJ2,KRIT1,RCBTB2,ARHGAP22,LHX2,AATK,PDE4DIP,RHOBTB1,PLPPR4,CHRDL1,IRAK4,MRNIP,STX2,FGF1,ANKFY1,DENND2A,KCNMB4,CNTRL,GRM8,INPP5B,MX1,PDE1C,STRN3,PTN,ENOX1,ZFP30,AMBRA1,FBXO11,CCDC88A,SS18,SYT1,TK2,ZNF711,NAV3,MPPE1,TIGD6" Drug 3431_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NME5,C1QTNF3,SPARCL1,SRPX,BEGAIN,DOC2A,PPFIA3,GYG2,CA4,FOXN3,STOML1,ARHGEF6,GREB1,ARHGAP32,DBT,TOM1,IQCG,GAD1,DISC1,SRCAP,GLYR1,POLL,HNMT,ITPKB,MIA2,RGS12,RXRA,ZNF821,FBXO11,COA1,PHLDB1,JMJD6,PLCB1,IQCE,TK2,TNS1,PLPPR2" Drug 208_DN SC-58125; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASIC1,ADORA1,OSBPL1A,APBB2,PPFIA3,CDK10,BCL7A,KYAT1,TAOK2,CLTB,PCYT1B,PPP6R2,DCAF8,C2CD2L,DYNC1I1,FEM1B,ING4,PIPOX,GRIK5,PRDM5,ICA1,KCNN1,MITF,MMP16,SNX10,CCDC25,SH3BP2,SLC11A1,ERC1,ZC3H13,CEP68,TBL1X,WSCD1,HEY1,KAT6B,METTL3,UBE3A" Drug 2166_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "SYN3,ADORA1,FAM135A,AMPD3,BIN1,RASL11B,SLC4A4,MPDZ,CFAP410,CACNA2D1,CDH2,CHRNA4,TAOK2,AATK,PDE4DIP,RIMS2,PLPPR4,CDON,CGREF1,ALDH1L1,GRM8,TJAP1,MAP4,MYO7A,NOVA2,NTRK2,ZCWPW1,RGS4,NEK11,SPTB,SYT1,WSCD1,SYNE1,VIPR2,VSNL1,CLIP2,GDPD5" Drug 7504_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NME5,CDC42BPA,CDK13,IL33,KYAT1,MYRIP,TBC1D5,DTNB,FEM1B,FCF1,TENM1,MRNIP,ETV1,FHL1,PDLIM5,ALDH1L1,MSL3,IL6ST,PCDH9,RETREG1,PRPH,CCDC40,MCMBP,ZNF821,MRAS,SLC14A1,ZBTB43,ATP10B,POGZ,SYT1,TIMP4,TK2,TNS1,TRIO,HIRA,VGF,ZNF74" Drug 7253_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "RALGAPA1,ASIC1,AMPD3,KCNAB2,DNAH17,MYRF,NRXN3,WHRN,VCAN,PDE4DIP,GIT2,CDON,ANKMY1,ZNF589,FYB1,ERAP1,POLL,CNTRL,ITGA7,KCNF1,KCNN1,MATN3,MBD1,SCAMP5,STRN3,SUPT20H,KDM4C,TROVE2,PLCB1,SYT1,DOCK9,TK2,TNS1,WNT7A,ZNF711,TFIP11,KAT6A" Drug 6402_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "PDE8B,AZGP1,CACNA1G,EPS15L1,AKAP5,CSF1,PDE4DIP,SEC14L5,SNPH,TMCC2,HIPK3,FCF1,C3orf18,NCALD,PIPOX,PTK2B,ADAMTS13,ICA1,KCNH2,MEF2C,MID1,ADAM22,MYO7A,NOVA2,P2RX7,SLC25A23,PLTP,PTCH1,ZSCAN2,TCP11L1,KCNIP1,IZUMO4,TNS2,PCDHA3,TPM2,LAT2,PHTF2" Drug 7264_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADCY6,ALK,KCNAB2,APC,ARRB2,BID,MTMR2,WASF1,RAB28,CSF1,ARHGAP24,GIT2,EGFR,IRAK4,PCOLCE2,COQ7,ZNF274,GLI2,HSF2,LIG4,LSS,NF1,MAPK7,GTDC1,AP1AR,AMBRA1,CHD9,PEX26,ZNF334,TMCC1,TROVE2,NXT2,SYT1,TRPS1,HIRA,EMSY,PHTF2" Drug 1870_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ZSCAN18,NCOA1,CFLAR,ST3GAL5,SYNJ2,CAPN3,SCARB1,SRSF11,FOXN3,QKI,CREM,DBT,TOM1,HIPK3,TNK2,COQ7,IGSF6,PTK2B,SCML2,ZNF589,GLYR1,LILRB4,CACFD1,MAP4,OCRL,GPR85,C12orf49,DGLUCY,FERMT1,SEC31A,EXOC7,TST,XRCC4,ZNF32,TFIP11,NT5M,EPM2A" Drug 6041_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AMPD3,BIN1,LGR5,ALDH7A1,CACNA1G,CALB1,KALRN,RIMS2,AASS,ST3GAL6,FHL1,PRUNE2,GRM8,GUCY1A1,HAS2,HLF,IRF8,IFI16,KCNJ5,AFDN,ADAM22,PCDHGC3,PPP1R1A,RELN,SAMD9,PTPRO,FRMPD1,SNAP25,ARC,SYT5,PCDHGB6,FAM189A1,OBSL1,OSBP2,LAT2,TIGD6,JPH3" Drug 2160_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG3,NDRG2,ADORA2A,PPFIA4,MARK4,NCOA1,ATP6V0A1,C5,SCARB1,RAB33A,PLAA,TPP1,STOML1,CNTN1,CSNK1E,SLITRK5,DZIP3,E2F5,CELSR3,MRNIP,FLT1,POLL,LILRA2,ITPKB,AFF1,MYT1,NEFH,SLC25A23,POU6F1,PTPRN2,EPN2,SLC11A1,KDM4B,DDN,PLCB1,PDLIM2,TPM1" Drug 2800_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,AK2,BIN1,SCAPER,SGCE,BAIAP3,CAMK2B,CD86,HOMER3,AKAP7,WHRN,CRMP1,ARHGEF4,DCAF4,MBNL2,TNK2,RCAN2,EFCAB2,OGA,GAD1,SRCAP,GFER,C2orf72,KCNB1,ZNF862,NTRK2,PPP5C,SNRK,KLHDC8A,EMID1,PKNOX2,KDM4B,PHLDB1,KIAA1107,PCDHGA10,KCNAB1,PARP11" Drug 6011_DN Hydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ARHGDIG,PDE8B,ARHGEF2,ZMYM4,B4GALT6,HOMER3,DBT,CDON,VPS26C,ANKMY1,DISC1,AHDC1,MALT1,RAB30,GRB10,ITPKB,KCNF1,MAP4,SETD4,KCTD15,PRODH,SAMD9,SH3BP2,EPN2,SPTAN1,IQSEC2,ASTN2,MTCL1,PCDHA6,PCDHA5,CHST8,ZKSCAN5,PLPPR2,VIPR2,XRCC4,HPS4,MPPE1" Drug 2565_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADCY6,APBB2,PPP4R4,RASL11B,KIF1A,AZGP1,MPDZ,FUBP1,CDO1,EPS15L1,ABI3BP,CSNK1E,EDNRA,CAMKK2,GATM,ZNF276,PADI2,KPNA5,ADAM11,MX1,NF1,OPRL1,SLC25A23,MINDY2,PPP5C,GDPD2,PTPN13,PTPRG,PTPRN2,TCP11L1,KCNIP1,ZNF821,ANKRD6,ZC3H13,TRIM2,TIAM1,SH3GLB2" Drug 4285_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,ALK,AMPD3,PKP4,EPB41L5,ADAM23,MTMR3,CDO1,SULT4A1,MRNIP,LRRC17,FOLR2,ALDH1L1,HTATSF1,VSIG4,KCNQ3,MAP4,MARK1,MMP16,FXYD7,PCDH9,PDE4D,PFKFB4,NECAB2,MAPK10,ZCWPW1,KCTD17,CNKSR2,SLC11A1,UNC5B,SYN2,ADGRL3,ZFPM2,TMPO,CDK20,VIPR2,WNT7A" Drug 4793_UP Zardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "SEMA7A,APBA2,APC,APOC1,ARNTL,ATP6V0A1,SYNJ1,CAST,NECTIN3,ING4,ACSL4,OLFM1,FGF13,PRKAG2,IQCG,DISC1,GRB10,ICA1,FAM69A,MAN2A2,RAP1GDS1,KCNIP1,SH3GL3,CCDC88A,LIMCH1,UHRF1BP1L,TROVE2,NXT2,NEK4,PLCB1,TLR4,TMPO,PIK3R5,SSBP2,CLDND1,ZFAND5,SLC17A7" Drug 5663_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADRA1D,BIN1,AMT,APOC1,BCAS1,ARRB1,ADAM15,CFLAR,SRSF11,TAOK2,MFAP3L,RCAN1,DTNA,EFCAB2,GLYR1,GPD2,MAP4K5,AGBL5,HNMT,MAPT,MPP2,ADAM22,PDE4A,SMIM7,PRKAR1B,TMEM231,SIRT2,LIMCH1,ARHGEF9,MCF2L,RPGRIP1L,AP4E1,TPM1,ZBTB14,ZNF24,EVI5,SMIM8" Drug 2473_DN Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APBB2,APC,NCOA1,ATP2A2,ARHGEF7,CAMK2G,FOXN3,IQCK,ABCG1,DBT,ZNF804A,DTNA,TUBD1,VPS26C,FYB1,GALC,INPP5K,DIDO1,ITGAM,IPO5,SCAMP5,CNOT4,OCRL,PILRA,CNNM2,SEC14L1,EPN2,SLC11A1,BTBD7,TROVE2,SS18,TACC1,ADGRL3,KIAA1107,SZT2,TLR4,PHTF2" Drug 5407_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "KCNAB2,CACNA1G,BAIAP3,CALB1,FOXN3,CSF1,RIMS2,CORO2B,FHL1,PRELID3A,NXPH3,ITPKB,KCNN1,MAP4,MPP2,MSR1,CNOT4,PLCD1,LRP12,NECAB2,PPP5C,CEP41,MAPK7,NKAIN1,SEMA6D,SH3BP2,SLC14A1,SNCA,TSNAXIP1,KDM4C,SAMSN1,KIAA1107,ZEB1,PCDHA3,TRPM2,ADAMTS9,KCNAB1" Drug 6563_UP PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APBA2,NRP2,CFAP410,CA12,ARHGAP22,CSF1R,CSNK1E,APH1A,SEMA4D,CAMKK2,CELF1,TMEM8B,GPER1,CACFD1,PADI2,MMP16,MN1,GIT1,NNAT,SMOX,MAPK10,PTPRH,KIRREL1,MAPK12,OGDHL,SPTAN1,SYT1,TRIM2,DICER1,PARD3,CABIN1,HIRA,WIPF1,LAT2,EMSY,HPS4,ACTR3B" Drug 1048_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "PPFIA3,STX16,SYNJ2,PTBP2,COL4A5,RNF14,SOCS5,DMTF1,E2F5,TSPAN5,EGR3,CDKL3,SCML2,NOP56,FAM49B,FYN,SEPT9,INPP5K,GLYR1,GRB10,FICD,JAK2,PCDH9,RETREG1,KCTD15,SMOX,MBOAT7,KLK6,NKAIN1,TRA2B,SGK1,SOX3,ZBTB43,KIAA0930,TRIM2,ZNF24,ZBTB38" Drug 2871_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,APBB2,GYG2,RCHY1,CRY2,ABCG1,SOCS5,FAM169A,DAPK3,HIPK3,ING4,RRAGB,ZNF589,MSL3,IL6ST,INPP1,KCNH2,MEIS2,ADAM22,NEK1,PPM1B,PPP5C,CNNM2,PEX26,PPP4R3A,ZKSCAN3,KDM4B,DOP1A,LHPP,CEP68,PLPPR2,ZNF74,DNALI1,EPM2A,ST7,ACTR3B,SENP7" Drug 2516_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "C1QTNF1,BIN1,CDC14B,PRX,ATP1A3,AZGP1,CFAP410,ARHGAP33,HAPLN1,ZNF337,SPOCK2,SNX29,CELSR3,ING4,DLC1,FGFR1,FGFR3,FHL1,ERAP1,SIGLEC8,HAS2,ICA1,IL6ST,SAMD14,NEFM,PRKAR1B,RFX2,RGS4,RGS12,SEC14L1,DOK5,SPART,TACR1,DNMBP,SLC35G2,TRO,SLC17A7" Drug 4161_UP Cefadroxil [50370-12-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ALK,APC,CDC14B,CFLAR,SYNJ2,BAIAP3,CDO1,AKAP7,AKAP6,SUSD5,VCAN,ARHGAP24,HEPH,DMD,DTNB,EDN1,VPS13B,ERBB2,F5,FAM49B,OGA,FYB1,GFER,RUNDC3A,GNAO1,PDE4D,ENPP2,PTPRD,CNKSR2,PKNOX2,IZUMO4,SPTB,CRTC1,TEK,CLIP2,XRCC4,AP3B2" Drug 7345_DN Alcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,CA12,SRSF11,QKI,AKAP7,ABCG1,DZIP3,PPP6R2,USP6NL,DBT,PHF20L1,EIF5,ENO2,STX2,ANKMY1,TXNL4A,MSL3,KCNMB4,HNMT,ITPKB,MAPT,KITLG,MKLN1,ZNF862,NFYA,PDE4A,RETREG1,ELOVL2,PTPRE,NEK11,EPN2,ZSWIM8,DIP2A,STX1A,NSFL1C,TRIM2,GAN" Drug 4829_DN Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADCY6,CDK10,ARRB2,ARHGEF7,NCOR1,SOCS5,APPL1,ARHGEF4,GPRASP1,ARHGAP32,DBT,MED12,DTNA,SUGP2,TNK2,DENND4A,ANKMY1,EZH1,FGFR1,CGREF1,INPP5K,ZNF276,GPR37,MPP2,SETD4,PCDH9,PLEC,PPP5C,PRODH,DCUN1D2,ABLIM3,TMCC1,ZBTB43,TACC1,BEX4,VGF,HPS4" Drug 3889_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NME5,EPB41L5,APOC1,CDK13,STX16,ADAM15,SYNJ1,ARHGEF7,CSF1R,MFAP3L,FCF1,ERCC2,RRAGB,FGFR1,SCARA3,IQCG,GCNT2,GLYR1,GRM8,GSN,ICA1,LSS,NF1,PIK3R1,LRP12,RNASEL,ASAP3,PEX26,ZKSCAN3,COA1,LHPP,PLCB1,EXOC7,TNS2,TMPO,MPPE1,PHTF2" Drug 6547_DN prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ACTN1,RGS20,MARK4,ADAM15,CFLAR,KRIT1,SCARB1,AKAP7,NRG2,TBC1D5,SPOCK2,TMCC2,DPH1,RCAN1,MAMLD1,FCF1,OPTN,ELN,FGF13,GUCY1B1,PALM,SERPINI1,MAPK7,WDR25,PTX3,SLC4A3,TMCC1,SMG6,TRIM2,SYNE1,GPR161,TNS1,AMACR,VGF,LAT2,MAP3K12,ACTR3B" Drug 2898_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "CDK10,GYG2,CACNA1I,CAMK2G,EPS15L1,RAB33A,SIPA1L1,CNTNAP2,EDN1,EGFR,ANKMY1,BAIAP2,OGA,GAD1,SYT17,SRCAP,GPER1,ICA1,KIT,CLDN11,PFKFB2,PRKAR1B,FAT4,GAL3ST4,KCTD17,KCNIP1,SALL1,RASA3,BTBD7,SLC22A4,ARFGAP1,LIMCH1,KDM4B,ARC,ZEB1,DOCK9,SLC30A3" Drug 7168_UP Diazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "GAS7,PLA2G4C,PTCH2,MPDZ,CFLAR,CBFA2T2,CLCN3,QKI,SLC4A8,AKAP12,NCOR1,SOCS5,PDE4DIP,RIMS2,RASSF2,LYPD1,MBNL2,DLC1,SEMA4D,GFER,COPS8,POLL,CACFD1,MIA2,PCDH9,STRN3,SAMD9,NEK11,RXRA,SYBU,KDM4C,SPART,CLASP2,AP4E1,TMPO,VIPR2,PHTF2" Drug 609_UP 5666823; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,BRAP,ADORA1,APOC1,PPFIA3,RGS11,RAB29,CHN1,EXTL2,TBC1D16,AFF2,STAU2,B4GALNT1,RNFT2,SLC2A6,KIF5A,MAP4,MAPT,NELL2,SETD4,PFKFB2,PLCD1,PPP5C,QDPR,GSTCD,PCMTD2,TCP11L1,GALNT10,SNAP25,HECW1,TROVE2,TBL1X,DMXL2,OBSL1,TNS2,GDPD5,DPF3" Drug 1702_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "STX16,ADAM23,GYG2,CRLF1,B4GALT6,SLC4A8,SH2B1,NCOR2,TBC1D5,GIT2,NR1D2,EIF5,BAIAP2,GNG4,TDRKH,ATXN2L,ELOVL5,HSF2,INPP5B,MAP4,NF1,PCDH9,PLCD1,LRP12,FBXO11,SLC6A8,BTBD7,CXXC4,LIMCH1,CDK19,SPART,THSD1,NXT2,CEP68,TMPO,ZKSCAN5,GAN" Drug 7419_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "APBB2,ARNTL,MARCH3,SLC4A4,USP2,QKI,AKAP7,ENTPD4,INTS1,GIT2,MFAP3L,DRP2,MRNIP,COQ7,ERCC2,SEMA4D,ZNF276,GLYR1,POLL,GPD2,RNFT2,MBD1,NFYA,SETD4,OXTR,MBOAT7,MAPK7,SCP2,CXXC4,SNCA,KDM4C,ARHGAP26,ELOVL4,SEPT8,PLCB1,EVI5,GDPD5" Drug 5249_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADORA1,SPARCL1,KSR1,CHRNA4,ABI3BP,ARHGEF4,TMCC2,ERCC2,DLC1,FHL1,ZNF44,NEU3,GFER,LYVE1,GLI2,POLL,LPAR4,GRM8,TJAP1,ADAM22,NNAT,NOVA2,PPARA,KHDRBS2,SUGCT,ZNF821,NLGN1,SLC11A1,SNCA,SYN2,WSCD1,CABIN1,CHST5,VIPR2,ADAMTS9,TIGD6,JPH3" Drug 4474_DN Sulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ALK,BIN1,APC,SHROOM2,MARK4,SCAPER,LY86,ENTPD4,AATK,GIT2,PARD6A,SPEG,BACH2,HNMT,MAPT,TM6SF1,NF1,PIK3R1,SLC25A23,PRKAR1B,ELOVL2,KIRREL1,CLIP1,SUPT20H,SH3BP2,BTBD7,UNC5B,SPTB,IQSEC2,ZBTB43,SYT1,IQCE,TMPO,WNT7A,ZNF24,EVI5,SEMA3B" Drug 205_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,SEMA6A,AQP6,CACNA1I,BAIAP3,CCNT1,CBFA2T2,LY86,HOMER3,CRMP1,NCOR2,ABCG1,ARHGAP24,DTNA,DUSP9,MBNL2,ING4,COQ7,NCALD,FGFR1,ZNF638,ADAM22,NTRK3,PLXNB1,MAPK3,CNNM2,RNASE1,MAPK12,STUM,ABLIM3,SLC2A5,SLC9A5,ELMO2,SPART,KIAA0930,DNAH7,WIPF1" Drug 308_DN sulindac sulfide; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,C1QTNF1,ALCAM,BEGAIN,OGT,APAF1,APBB2,AQP6,ATP6V0A1,SYNJ2,CHGB,CNTN1,TBC1D5,TMCC2,ERBB4,ETV1,EXTL2,MAN1B1,AFF1,ADAM22,NF1,NOVA1,PRKCB,MAPK3,PRPH,MTMR10,PBRM1,RNASEL,ZNF821,SH3BP2,KBTBD4,SNAP25,SNCA,HECW1,VPS13A,TRPM2,ZNF195" Drug 2356_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AMH,BIN1,ANK2,APBB2,APOC1,CDK13,KIF1A,KSR1,ARHGAP33,TAOK2,CREM,ZFYVE16,ZNF337,SPOCK2,EDNRA,CELSR3,MBNL2,RASGRP2,F5,ZNF44,ZNF276,MSL3,TM6SF1,MYH3,MYO6,PFKFB2,PLTP,PMP22,PNMA8A,FERMT1,SLC11A1,BTBD7,SNCA,WSCD1,SIN3B,TK2,ICAM5" Drug 1389_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "NDRG2,OGT,APBA2,CDC14B,CFLAR,CD86,SEPT7,EPS15L1,CNTN1,SPOCK2,SRPK3,CDKL3,EZH1,MPP6,SPIN1,GLYR1,INPP5B,MAN2A2,MAP4,TAGLN3,NPY,CNNM2,DEF8,RNASEL,NEK11,SH3BP2,CCDC88A,ZHX3,PEG10,ST5,PHF24,TMPO,R3HDM1,KAT6B,CHST5,LAT2,SLC17A7" Drug 7386_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "CFLAR,MYRF,ARHGEF2,IQCK,BAG4,ENTPD4,PPP6R2,CDON,FEM1B,SPEG,ATP2C1,DENND2A,COPS8,GPER1,INPP5B,LIG4,BCAS3,RAD51D,MCMBP,SBF1,SCN8A,FAM214B,KDM4D,KBTBD4,BTBD7,LIMCH1,ARHGAP26,ZBTB43,ELOVL4,CEP68,KIAA0930,SYNE1,NSD1,TIAM1,BHLHB9,UPF3A,MAP3K12" Drug 6399_UP C75; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "KDM5D,APC,CDK10,DNAH17,ATP6V0A1,RGS11,BAIAP3,LHX2,HOMER3,WHRN,ABCG1,SLITRK5,MFAP3L,FRY,NCALD,HPCAL4,TDRKH,FAM107A,ITGA7,KCNQ3,NF1,NTRK2,PDE4D,CEP41,PRKAR1B,PTPRN,C1orf54,BEND5,RNASE1,SLC6A11,ZSWIM8,DDN,ARC,TBCEL,CDK20,CA14,SPHK2" Drug 4673_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "PPFIA4,APBB2,ARRB2,ADAM23,CACNA1G,CAMK2B,SYNGR3,AKAP7,SH2B1,ARHGEF10,VCAN,SGSM2,DTNA,CDKL3,ST3GAL6,AFF2,FYB1,ZNF44,GPR37,MAPT,AFF1,MAPK7,SAMD9,ELOVL2,SUGCT,ZNF671,MCMBP,NLGN1,ARHGAP26,SPTAN1,DDN,LHPP,THRA,TIAM1,TNS1,WIPF1,TIGD6" Drug 1713_DN Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; HL60; HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "C1QTNF1,STX16,SPAG9,FOXN3,MAP4K4,RAB26,ARHGEF10,SPOCK2,SGSM2,IGSF6,FGFR1,BAIAP2,NEU3,PRRC2B,DIDO1,SPACA9,IDH3A,MAP4,MBD1,MEF2C,SCAMP5,AFF1,NTRK3,ZNF426,PPP2R2B,RAD51D,EXD2,AMBRA1,SNAP25,ZSWIM8,THSD1,MCF2L,CABIN1,VGF,EPM2A,ST7,AAAS" Drug 5397_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "RALGAPA1,AP2A2,SYT13,AMPD3,CDC14B,ADAM23,CACNA1I,CACNA1A,CAMK2G,CHN2,CNTFR,OSBPL3,RIPOR2,PTK2B,PRELID3A,CHL1,ADAM28,GLYR1,PCLO,RASSF8,TJAP1,KCNN1,SMAD1,NELL2,NPY,PTCH1,TRIM68,SBF1,PEX26,FAM214B,SLC14A1,SMARCD3,RBM34,MCF2L,R3HDM1,TRIO,TRO" Drug 6758_DN Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ABR,ARHGDIG,SPAG9,ARHGEF1,NRXN3,TPP1,QKI,HOMER3,NCOR2,DAPK3,GIT2,MFAP3L,SPEG,ZNF589,FGFR1,ANKFY1,SEPT9,MSL3,GPD2,GUCY1B1,LSS,MIA2,TAGLN3,PIK3R1,MINDY2,PTPRN2,RIPOR1,FBXW7,SUPT20H,SLC14A1,LIMCH1,ARHGAP26,TRIM2,RPGRIP1L,UGT8,EVI5,PHTF2" Drug 2692_UP troglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,AZGP1,CACNB4,EPS15L1,NCOR2,ARHGEF10,VCAN,PDE4DIP,DGKG,PARD6A,EDN3,AFF2,EFCAB2,CSPG5,SIGLEC8,GPD1,GSN,ATXN2L,MID1,MSR1,LYRM9,PCDH9,PPARA,MAPK7,PTH1R,ZSCAN2,CCDC40,RASGRF1,SUGCT,EMID1,PHF24,ZNF34,TPM1,CA14,TUBB1,ZNF225,EVI5" Drug 438_UP copper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ACTN1,KIAA1324,SYT13,APC,SLC4A4,ATP6V0A1,SYNJ2,CACNA1I,CHN2,TAOK2,DAPK3,DRP2,SEZ6L2,HIPK3,IRAK4,PDLIM5,ZNF276,LUZP2,GRIK5,SOX21,LAMP2,PTOV1,NLE1,PLEC,MBOAT7,PPP5C,MAPK3,RNASE1,SH3BP2,CLASP2,TRIM2,TRPM2,WNT7A,ZNF24,TFIP11,ACTR3B,AAAS" Drug 5111_DN Scoulerine [6451-73-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ALDH7A1,FUBP1,PDE4DIP,CDON,HIPK3,ANKMY1,SCML2,BAIAP2,PCYOX1,SEMA4D,MSL3,POLL,PCLO,GUCY1B1,IFI16,FAM69A,MEF2C,TAGLN3,NFIX,STRN3,PPARA,CNTLN,PTX3,BEND5,ZNF671,CSRNP3,SUPT20H,ZFP30,SMARCD3,CAMTA2,TCF4,TMPO,ZNF225,NT5M,SLC17A7,PHTF2,SENP7" Drug 2038_UP Danazol [17230-88-5]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "SYT13,PDE8B,SLC4A4,ADGRB2,CACNA1I,MYRF,CA12,CACNA1A,CALB2,SPAG9,CNTFR,IQCK,TMCC2,ELN,BAIAP2,ALDH1L1,SPACA9,CACFD1,KCNF1,LAMA2,GIT1,SAMD14,NTRK3,PFKFB2,DUSP26,RNASE1,RXRA,LIMS2,SLC6A11,SLC11A1,SNAP25,ZC3H13,SPTB,SYN2,CA14,VGF,VIPR2" Drug 6725_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AGT,ALK,APAF1,CDK13,SLC4A4,CFAP410,CBLN1,MAGI1,CHRNA4,EPS15L1,CNTFR,CRY2,SUSD5,TBC1D5,SPOCK2,FGF1,FGFR1,TRMO,OGA,GPR75,IL12A,LAMA2,MT1M,TAGLN3,ENPP2,DUSP26,PPP5C,CCDC40,ENOX1,CNKSR2,PREX2,ZNF334,IQSEC2,CDK19,AP4E1,VAV1,PARP11" Drug 6198_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "SEMA6A,APC,LGR5,PDE8B,NCOA1,CACNA2D2,SULT4A1,FAM149A,SIPA1L1,DZIP3,EDNRA,MBNL2,ANKMY1,REEP2,FGF12,KHDRBS3,GPD1,PCLO,GRM8,GSTM5,AP4S1,HAS2,NNAT,NRCAM,SERPINI1,RETREG1,PURG,SEMA6D,FAM102A,ZSWIM8,OBSL1,TEK,TK2,TRIO,KCNE5,RPRM,UBE3A" Drug 2849_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AMPD3,CDC14B,CDK10,EIF4G3,CFLAR,CFAP410,CAMK2G,SRSF11,PLEKHB1,TAOK2,CLCN3,HOMER3,NCOR1,LRIG1,DAPK3,GIT2,ACSL4,ZNF589,FGFR1,TXNL4A,JAK2,NPTX1,PLEC,LRP12,ZDHHC14,GTDC1,RXRA,SBF1,CDK19,VPS13A,ARC,ANKRD28,ASTN2,EXOC7,IQCE,TRIO,PHTF2" Drug 6813_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASIC1,LTBP4,AMT,SYNJ1,HIP1R,ARHGEF1,ARHGAP33,CLGN,RCBTB2,SULT4A1,LY86,RCHY1,CPS1,VCAN,MAML1,DAPK1,SPOCK2,GIT2,DMPK,DTNB,HNMT,ICA1,MID1,TCP11L1,ABLIM3,BTBD7,KIF13A,FAIM2,DOP1A,PDZD2,CLSTN2,SYT5,SYNE1,OBSL1,UCHL1,OSBP2,KAT6A" Drug 3138_UP Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ADORA1,MTUS1,CDC42BPA,ATP6V0A1,RGS11,HAP1,EPS15L1,CELSR3,EGFR,ELN,ZNF549,OLFM1,FGFR3,GNAO1,PRUNE2,GPR12,TJAP1,KCNJ5,MPP2,NPY,NRCAM,BCAS3,PTPRN2,RIPOR1,RGS4,RGS12,MAP6D1,SH3BGR,ST6GAL1,SLC11A1,CXXC4,TMCC1,ATP10B,SYNE2,EXOC7,TRIM2,FLRT2" Drug 1363_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "BRAP,BACH1,CAST,KRIT1,CBFA2T2,SRSF11,CREM,SOCS5,PPP1R16B,GIT2,SGSM2,ERCC2,VPS26C,ATP2C1,MPP6,INPP5K,GSTM5,IPO5,KTN1,MAP4,NTRK3,ENPP2,SNX10,RETREG1,TRHDE,POLG,PPM1B,ZC3H14,ELMO2,SLC22A4,ZSWIM8,TSPYL2,PHLDB1,FBXW11,TCF4,WRN,JMJD1C" Drug 5312_UP Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ABHD6,ALCAM,APOC1,PPFIA3,KIF1A,CFLAR,FOXN3,TAOK2,VAX2,QKI,PDE4DIP,GREB1,EGFR,EGR3,COQ7,B4GALNT1,GFER,POLL,IL6R,KHK,LSS,MAPT,ADAM22,NFYA,OGG1,RET,TCP11L1,COA1,KDM4B,PHLDB1,DNMBP,TRIM2,KAT6B,CDK20,VIPR2,GDPD5,HPS4" Drug 4024_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "EPB41L5,CDC14B,ADGRB1,CFLAR,HAP1,CCK,CSNK1E,SEC14L5,HIPK3,EGFR,ETV1,OLFM1,PRELID3A,ERAP1,SIGLEC8,PACRG,MATN3,TM6SF1,MMP16,NEFM,NPY,BEND5,RBBP6,GAL3ST4,GSTCD,MRAS,LIMCH1,CRTC1,R3HDM1,TNS1,TPM1,CHST5,VGF,VIPR2,ZNF24,KCNAB1,DPF3" Drug 7049_UP AH6809; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,GAS7,PPP4R4,MADD,FUBP1,KALRN,RCBTB2,MFAP3L,EDN1,FAM13A,SUGP2,ING4,VPS26C,FYB1,MSL3,STON1,HNMT,SHISAL1,INPP5B,KHK,FSD1,PRPH,PTCH1,GAL3ST4,PEX26,SLC9A5,ZNF667,ARHGAP26,PBLD,SEPT8,VPS13A,PLPPR2,VGF,REEP1,NT5M,SMIM8,RNF146" Drug 5357_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASIC1,ALK,BCL7A,CFLAR,ST3GAL5,CAMK2G,NCOR2,PDE4DIP,DOCK4,GIT2,F5,DLC1,FGF12,SPACA9,CLASRP,ITPKB,KCNF1,MAPT,MIA2,GIT1,SETD4,POLG,NEK11,AMBRA1,PPP4R3A,PKNOX2,SMARCC2,ZBTB43,CLSTN2,CEP68,ARC,EXOC7,PLPPR2,VIPR2,TFIP11,EVI5,GDPD5" Drug 1977_UP Miconazole [22916-47-8]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ACTN1,BRAP,ARHGEF7,SRSF11,SEC31B,CREM,SOCS5,CTH,PPP6R2,TM9SF4,SUGP2,EIF5,ING4,FCGRT,FKTN,UFM1,ATP2C1,SARAF,MPP6,SRCAP,DIDO1,IRAK3,NFYA,GPSM2,PLCD1,PRKAB2,SNRK,PPP4R3A,SLC11A1,UHRF1BP1L,POGZ,SS18,KLHL7,TMPO,R3HDM1,ZNF189,HPS4" Drug 7228_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ASIC1,ADORA2A,AP2A2,AK2,ALK,SEMA7A,N4BP2L1,BAIAP3,HAP1,STOML1,SLC4A8,GIT2,SPOCK3,DUSP9,HSD17B14,OGA,FYB1,DISC1,NEU3,SPACA9,IRF8,TM6SF1,AFDN,TAGLN3,GPR85,PRKAR1B,ZSCAN32,EMID1,PKNOX2,PHLDB1,PLCB1,SYT5,ANKRD12,PIK3R5,ZKSCAN5,SLC17A7,ST7" Drug 7260_UP Ethamivan [304-84-7]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,MTUS1,STX16,STOML1,QKI,GIT2,DPH1,EGFR,ERCC2,ZNF391,BAIAP2,CGREF1,FYN,MAN1B1,ATXN2L,TJAP1,INPP5B,ITPKA,LIG4,MBD1,SLC11A2,MAPK7,WDR37,SNCA,TMCC1,UNC5B,NXT2,CEP68,VPS13A,SYT1,TCF4,HIRA,ZBTB14,EMSY,EPM2A,FAM13C,KAT6A" Drug 4587_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "MTUS1,BBOX1,TRMT9B,APAF1,ATP2B2,CACNA1I,HAP1,CAMK2B,SLC16A4,VCAN,DTNA,DTNB,EDN1,ERGIC3,NSG1,SRCAP,GNAO1,FAM69A,ITGA7,LIG4,LMO2,MX1,NF1,PALM,PDE4D,MINDY2,LRRN3,KCTD17,CCDC102B,OGDHL,TROVE2,ADGRL3,PHF24,PCDHA5,AP4E1,WIPF1,EPM2A" Drug 2543_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "ABR,NDRG3,CDK13,MARCH3,SCAPER,MTMR2,QKI,C2CD2,CSNK1G3,DBT,SPATA2,SGSM2,DTNA,FRY,EPB41L2,F8,ARFIP1,GLYR1,IL6R,MEST,GIT1,NFYA,SLC11A2,OCRL,PIK3R1,ZFYVE21,RETREG1,LRP12,PPP5C,TCP11L1,PPP4R3A,ZBTB43,ITPRID2,NXT2,DIP2A,IQCE,TCF4" Drug 2235_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "AP2A2,APBB2,APC,MTMR3,ARHGEF2,MAGI1,AKAP7,CSF1R,SIPA1L1,KIAA0586,MFAP3L,BAIAP2,FHL1,IQCG,GLYR1,POLL,CACFD1,GSTM5,IL6ST,INPP1,MYO7A,CDK18,PRODH,RPS6KA2,ABLIM3,BTBD7,THSD1,ELOVL4,JMJD6,VPS13A,ARC,RPGRIP1L,PCDHA6,ZNF34,SPHK2,KCNAB1,KAT6A" Drug 168_DN sulindac; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 1.43E-03 1.00E+00 1.09E-02 1.23E-01 37 197 "CDK10,BCL7A,CFLAR,WASF1,MYRF,CFAP410,HIP1R,UBE2L6,TAOK2,NCOR1,NCOR2,CSNK1E,YAF2,COQ7,ZNF589,FGFR3,SEC23B,TRMO,GRIK5,FAM107A,ATXN2L,MYT1,SETD4,MBOAT7,PPP2R3C,RASGRF1,MAPK12,ZNF821,SH3BP2,LIMS2,KDM4B,GLT8D1,STX1A,TK2,CBX5,KAT6B,CHST5" Drug ctd:D011224 Prazosin CTD 1.45E-03 1.00E+00 1.11E-02 1.25E-01 16 63 "ADORA1,ADORA2A,ADRA1D,ADRA1B,ATP2A2,ABCG2,EDN1,PPARGC1A,IGF1,NPY,ABCB1,PKM,PLCD1,MAPK3,SLC8A1,PLCB1" Drug 4590_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 1.13E-02 1.27E-01 34 177 "C5,IL33,ARHGEF2,EPS15L1,WHRN,CREM,AKAP12,ABCG1,CSNK1E,PHF14,CTH,PITPNC1,DTNA,ETV1,GPD1,SHISAL1,ITGA7,JAK2,NRCAM,PALM,PDE4B,PDE4D,SMOX,PMP22,PPP3CA,RGS12,CCDC102B,RBM34,TSNAXIP1,DOK5,ATP10B,TBL1X,DNAH7,OSBP2" Drug 4495_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 1.13E-02 1.27E-01 34 177 "PRX,SLC4A4,C5,IL33,STOML1,WHRN,CREM,AKAP12,PHF14,CTH,ARHGEF4,PITPNC1,NCALD,ETV1,ARMCX1,DLC1,GPD1,GRIK5,CACFD1,PADI2,IRF8,JAK2,NPY,PDE4B,PDE4D,SMOX,PMP22,ZSCAN32,AP1AR,ZHX3,TBL1X,CRTC1,TNS1,ZBTB38" Drug CID000234384 alph a- Stitch 1.50E-03 1.00E+00 1.15E-02 1.29E-01 17 69 "ADRA1D,ADRA1B,ADRB2,CAPN3,CBS,CBFA2T2,PICK1,CRYBB1,LYPD1,DMD,FKTN,LAMA2,GSTCD,SPTB,TUBA1A,NELFE,NETO1" Drug CID011708451 2 IMA Stitch 1.51E-03 1.00E+00 1.15E-02 1.29E-01 12 41 "APLP1,STX2,GABRG2,NOVA2,PLEC,PKIA,ELOVL2,PTPRN,SCN2B,STX1A,GORASP1,ST8SIA2" Drug CID004470173 AC1NBM3D Stitch 1.51E-03 1.00E+00 1.15E-02 1.29E-01 12 41 "ADORA2A,CNR1,CST3,BOC,KCNH2,MID1,P2RX7,PTCH1,SSTR1,SSTR2,TUBA1A,HPS4" Drug CID000043234 propiconazole Stitch 1.51E-03 1.00E+00 1.15E-02 1.29E-01 12 41 "LARGE1,CLASRP,FICD,KIF2A,FSD1,CLIP1,MRAS,CLASP2,TBL1X,CLASP1,TMEM121,CLIP2" Drug ctd:D008774 Methylphenidate CTD 1.51E-03 1.00E+00 1.15E-02 1.30E-01 27 131 "RGS20,CHID1,LARGE1,CNR1,NCOR2,SNCAIP,DAPK3,IP6K1,EXOG,CNNM1,GHDC,DHX35,KIFC3,NTRK2,SLC10A4,RET,SNX22,EPHA10,PEAR1,GALNT10,SNAP25,SOX11,ARC,AGTPBP1,CHST8,STOX2,NETO2" Drug ctd:D009020 Morphine CTD 1.51E-03 1.00E+00 1.15E-02 1.30E-01 72 448 "ADCY6,ADCY8,TMCC3,ADORA1,ADORA2A,AGT,BCAS1,ARRB2,CALB1,CAMK2A,CBLN1,CCK,CD38,SEPT7,NRXN3,ABCG2,CNR1,CREM,RGS6,CYBB,DPYSL2,EGR3,RGS17,NRN1,PPP1R1B,FGFR1,GABRG2,GAD1,GCNT2,CSDC2,GRIA2,PLCD4,GRIN2C,FAM107A,HP,IDH3B,SOWAHA,IL12A,MAP2,MAPT,FXYD7,NEFH,NPY,NRCAM,OPRL1,GNG2,ABCB1,PLCD1,PRKCB,MAPK3,RELN,RGS4,S100B,SGK1,SNCA,SST,SEPT8,PHLDB1,PLCB1,SYT5,TACR1,PDLIM2,CUX2,SYNE1,CDH22,TLR4,BEX4,PRR18,CCDC136,ZIC1,SLC17A7,GJC2" Drug 3244_UP Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.51E-03 1.00E+00 1.15E-02 1.30E-01 35 184 "C1QTNF1,LTBP4,APBA2,APBB2,PPP4R4,RGS20,ST3GAL5,CBFA2T2,RCBTB2,SOCS6,RIMS2,DTNA,MBNL2,EPB41L2,IGSF6,GALC,SRCAP,STON1,GPER1,GPR37,HMGCR,INPP5B,ZNF862,PCDH9,PLCD1,STRN3,ELOVL2,SLC2A5,ZNF423,TACC1,TBCEL,SZT2,PCDHA5,RUNDC3B,KAT6A" Drug 4439_UP prochlorperazine dimaleate salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.51E-03 1.00E+00 1.15E-02 1.30E-01 35 184 "NDRG2,ADRA1D,PDE8B,CBS,CDO1,SULT4A1,CTH,SNX29,CELSR3,ETV1,REEP2,ST3GAL6,GLI2,FERMT2,GRB10,IL6ST,KCNF1,KCNH2,MAP2,MT1M,POU6F1,PPARA,SNRK,PTPRN2,MARCH1,C1orf54,GAL3ST4,RGS4,RNASEL,FAM214B,ARHGAP26,PLCB1,SYT1,TCF4,VSNL1" Drug 1007_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.51E-03 1.00E+00 1.15E-02 1.30E-01 35 184 "C1QTNF3,LTBP4,APBB2,EPB41L5,FAM131A,CDC14B,FOXN3,PLEKHB1,FAM189A2,LRIG1,PDE4DIP,DTNA,MBNL2,VPS26C,BRD8,STON1,HNMT,KITLG,MXI1,PRKAB2,PTCH1,CEP97,CARF,TCP11L1,ZFP2,KDM3A,CDK19,THSD1,NXT2,CEP68,CRTC1,NR2C2,VGF,ZNF23,EMSY" Drug ctd:D004026 Dieldrin CTD 1.52E-03 1.00E+00 1.15E-02 1.30E-01 172 1221 "ACTN1,AXIN2,FZD9,ADRB2,MTA3,AGT,TXNDC16,ALK,BIN1,APAF1,APBB2,APLP1,VAT1L,CDK10,ARRB2,CDK13,PTCH2,ATP2A2,ALDH7A1,BID,LDHD,DST,GYG2,CAMK2A,CAMK2B,CAMK2G,CAPN3,PRC1,KYAT1,CERS5,CCNH,CCNT1,SLC16A4,SCARB1,DGKI,LRBA,SEPT7,CDC25B,CDH2,DCLK1,CCPG1,FOXN3,CHGB,CHRNA4,PPT2,ABCG2,ARHGEF6,CNRIP1,CRHBP,LRRC3B,CSNK1E,SIPA1L1,ERC2,BOC,BRINP1,DNAL1,ALKBH8,PARD6A,CASP8AP2,FIS1,E2F5,FEM1B,EGFR,ASB3,EIF4G1,PLEKHA1,TUBD1,STX2,ACSL4,FGF1,FGF12,FGFR1,PCYOX1,FOXO3,DCTN2,POMT1,MPP6,FYN,GABRB3,GABRG1,GABRG2,MSTN,SESN1,NFU1,GFER,MMADHC,GRIA2,GRIN2C,ATE1,CIT,FICD,IRAK3,HBA1,IDH3B,IGF1,SCIN,CREG2,KIT,SFXN5,SYTL4,MAPT,AQP11,MBP,TM6SF1,AFF1,COMMD5,MYCN,NEFM,NEFH,NPY,NPTX1,NTRK2,NTRK3,OPA1,P2RX7,PDCD2,ABCB1,PMP22,POLR2F,MAPK3,MAPK10,SLC26A11,APTX,PTN,PTPRO,NKAIN1,RET,GTDC1,KIF7,ELP2,ZC3H14,RXRA,TRAPPC13,SALL1,MAPK12,SMPD3,FOXRED1,SGK1,ST6GAL1,SLC6A8,SIRT2,CDK5RAP3,SLC12A4,ABTB1,SMARCA4,SNAP25,SNCA,FAIM2,LMBRD1,RBM34,KDM4B,UNC5B,ERBIN,STXBP1,JMJD6,PLCB1,ZMAT3,SLC44A1,CDK20,PDSS1,TSC1,TSC2,BCL2L13,MTCH1,VIPR2,WNT7A,POLR3H,MFF,SLC38A1,FZD3,RTN4,FXR1" Drug CID000656725 reactive blue 2 Stitch 1.52E-03 1.00E+00 1.16E-02 1.30E-01 20 87 "ADORA1,ADORA2A,APC,CACNA1B,P2RX6,ENTPD2,PLCXD3,DMPK,HPGDS,LPAR4,PLCD4,AGFG1,P2RY13,P2RX7,P2RY1,PLCB2,PLCD1,PLCB1,VIPR2,P2RY12" Drug CID000024083 magnesium sulfate Stitch 1.55E-03 1.00E+00 1.17E-02 1.32E-01 14 52 "ATP2A2,CACNA2D1,TUBD1,GPHN,TUBB3,TUBA8,CBX1,STON1,GRIN2C,GRIN2D,IPO5,TUBB2A,TUBB1,TUBA1A" Drug 7045_DN lomustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "ASPHD1,ASIC1,AP2A2,LTBP4,CDC42BPA,EPB41L5,APOC1,MARCH3,SLC4A4,SCAPER,CACNA1I,CD86,LHX2,QKI,CSF1,PDE4DIP,ARMCX2,RGS17,ARMCX1,DLC1,GLYR1,JAK2,MGAT3,PDE1C,PMP22,PKIA,SNRK,TMEM104,RGS3,EMID1,FUZ,TACC1,KAT6B,RPRM,GDPD5,PLSCR4" Drug 4303_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "NME5,ALDH7A1,SPAG9,SRSF11,RAB26,FAM169A,NR1D2,EDIL3,FCF1,MBNL2,ING4,SEMA4D,CRCP,RASSF8,AGFG1,IL6ST,MAP4,NFIX,PIK3R1,STRN3,LRP12,WDR25,SLC25A36,SEC14L1,FBXO11,CCDC88A,ZNF667,ARHGEF9,TBL1X,TCF4,TRIM2,DICER1,TMPO,WNT7A,ZBTB38,KAT6A" Drug 5953_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "TRMT9B,BIN1,OGT,CA4,SLC16A4,CBFA2T2,SCARB1,RCBTB2,PLAA,QKI,SH2B1,LRIG1,TBC1D5,DGKG,RUSC2,RCAN1,MBNL2,ZNF589,SRCAP,ADAM28,POLL,DIDO1,TJAP1,MMP17,NF1,MBOAT7,SAMD9,ZSCAN32,HSPA4L,SH3BGR,ZEB1,OBSL1,PCDHA5,AP4E1,UCHL1,ZFP37" Drug 4437_DN 17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "C1QTNF3,LTBP4,MARK4,ADAM23,ADGRB2,BMPR1B,HIP1R,PLEKHB1,RAB26,HAPLN1,EDIL3,MRNIP,STX2,NCALD,SCARA3,HAS2,MAPT,MIA2,NF1,PFKFB4,PIK3R1,PLCB2,MAPK7,WDR25,PTPRH,KIRREL1,PPP4R3A,KDM4D,ARHGEF40,DDN,TROVE2,ASTN2,TMPO,ZBTB14,TRIM9,NT5M" Drug 6693_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "AGT,SPARCL1,BCAS1,ATP1A3,CFLAR,SCAPER,CACNA2D1,MTMR7,QKI,PCYT1B,CSF1,SUSD5,PHF14,CTH,MFAP3L,HIPK3,ZNF589,FGFR1,SIGLEC8,GLI2,MX1,CNOT4,PIK3R1,LRRN3,MARCH1,RGS4,RPS6KA2,FRMPD1,FAM214B,CXXC4,ZSWIM8,SPTB,SYT1,ZNF24,PRDM10,GAN" Drug 993_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "OSBPL1A,C1QTNF3,BIN1,PPFIA3,CDC14B,RGS20,CFLAR,CAMK2G,MAGI1,TPP1,CABP1,DAPK3,MFAP3L,LYPD1,EIF4G2,FLNC,AFF2,B4GALNT1,SRCAP,GLYR1,GNG4,GRIK5,DHX35,MSR1,HSPA4L,SH3BGR,TSPYL2,TROVE2,TTBK2,VPS13A,TRIM2,SZT2,DICER1,RUNDC3B,VLDLR,FXR1" Drug 3966_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "LTBP4,KCNAB2,PPP4R4,CDK13,BMP7,ST3GAL5,SOCS6,CSF1,RIMS2,HIPK3,FEM1B,RASGRP1,EGR3,CDKL3,EZH1,FGFR1,FAM49B,ADAMTS13,ELOVL5,HNMT,KCNF1,NPTX1,PFKFB3,STRN3,MINDY2,RET,ZNF821,FAM214B,KDM4B,PLCB1,MTCL1,MCF2L,EXOC7,SZT2,ZNF34,TK2" Drug 4298_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "NDRG3,CDK13,STX16,KIF1A,ADAM15,CFLAR,IL33,SPAG9,HOMER3,CRMP1,DZIP3,HIPK3,EGFR,ING4,RGS17,FGFR1,FHL1,ANKFY1,FAM49B,FYN,GRIK5,SOX21,GUCY1B1,NXPH3,ATXN2L,HSF2,INPP5B,LIG4,CNOT4,CLDN11,ZNF426,POGZ,TMPO,TNS1,SSBP2,SEMA3B" Drug 1561_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "ARNTL,MARK4,ST3GAL5,WASF1,CAST,PPP1R16B,DOCK4,DBT,FAM13A,GOLGA7,ENO2,RASGRP2,FGFR1,DBF4,HTATSF1,AGFG1,IFI16,ITGA7,ITGAM,MEF2C,CCSER2,SLC25A23,PTK2,PTX3,SEC14L1,ELMO2,SPATA7,CDK19,SAMSN1,CEP68,STXBP1,KLHL7,TACC1,PDLIM2,TPM1,EVI5" Drug 2824_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "ADRA1D,BIN1,APBA2,APC,BACH1,CFLAR,CAMK2B,UBE2L6,QKI,AKAP5,MFAP3L,TMCC2,HIPK3,NCALD,BAIAP2,OGA,FYN,TMEM8B,MSL3,GSN,IL6ST,KCNH2,MITF,CNOT4,CLDN11,MBOAT7,MAPK10,C1orf54,RPS6KA2,EMID1,ASAP3,PREX2,PEX26,SLC14A1,SPHK2,SENP7" Drug 3665_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "APC,SEMA4G,SLC4A4,IL33,HAP1,CBFA2T2,SCARB1,SOCS6,ARMC8,SH2B1,HAPLN1,SLITRK5,GPRASP1,RHOBTB1,EDNRA,CNNM1,SCARA3,SRCAP,GPER1,HAS2,MT1M,PRPH,PTN,ENOX1,GAL3ST4,ZNF821,PPP4R3A,CEP68,COBL,EXOC7,TCF4,TMEM121,TK2,SMUG1,WNT7A,RNF146" Drug 3291_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "C1QTNF1,SRPX,ALK,SEMA7A,APLP1,CAMK2B,ARHGAP33,FOXN3,ARHGEF6,WHRN,CRMP1,VCAN,CNTNAP2,LRRC17,FHL1,SIGLEC8,GNG4,ADAMTS13,GRIK5,KCNJ5,KCNQ3,MAP4,MATN3,MEF2C,ADAM22,CLDN11,PPP2R2B,CEP41,TCP11L1,SLC6A8,SLC9A5,SNCA,CLSTN2,PHLDB1,PDIA2,NLRP3" Drug 3803_DN Flutamide [13311-84-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "IL33,ARHGAP33,CSF1,MFAP3L,EXOG,DTNA,EDIL3,NCALD,FGF1,SEMA4D,TRAF3IP2,SHISAL1,LIFR,MATN3,TM6SF1,SCAMP5,ADAM22,CNOT4,PIK3R1,STRN3,ZCWPW1,RXRA,ASAP3,FAM214B,BTBD7,SNCA,ZHX3,ZEB1,RPGRIP1L,TMPO,TNS1,TRIO,ZNF24,REEP1,EPM2A,SENP7" Drug 3377_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-03 1.00E+00 1.17E-02 1.32E-01 36 191 "ADORA1,ARHGEF2,PLEKHB1,CNTN1,ERC2,DAPK3,ARMCX2,JAKMIP2,HS3ST2,EDN1,EGR3,HSD17B14,ERBB2,ERCC2,REEP2,DISC1,GCNT2,ITGAM,JAK2,KCNH2,MGAT3,AFF1,MX1,NPR2,PCDHGC3,PLCB2,RET,SH3BP2,PKNOX2,ARHGAP26,CDK19,VGF,VLDLR,LAT2,SEMA3B,EPM2A" Drug 1551_UP Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APBA2,ARNTL,SCAPER,KRIT1,CCNT1,ARHGAP33,SRSF11,CNTFR,BAG4,SEC31B,CLOCK,KLHL3,ANKRD46,EGR3,ING4,EPB41L2,SEC23B,INPP5K,CRCP,ITGAM,MYT1,NEFH,CNNM2,CCDC40,AP1AR,ELMO2,ZC3H13,TSPYL2,LARP4,CEP68,SYT1,MCF2L,PARD3,TRIM9,EVI5,AAAS,DPF3" Drug 3680_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,C1QTNF3,CDC42BPA,CDK10,NRG2,CREM,VCAN,HDAC9,SGSM2,DMPK,MBNL2,ANKMY1,CINP,GCNT2,CACFD1,ELOVL5,KCNB1,KHK,TAGLN3,NF1,RETREG1,PLEC,TCP11L1,SAFB,SATB1,FUZ,ELMO2,SNCA,CDK19,ARC,FBXW11,TRIM2,DNAH7,PLPPR2,LAT2,XRCC4,NAV3" Drug 4977_UP SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NME5,AK2,LTBP4,TRMT9B,APBA2,APC,SLC2A11,SYNJ2,CACNA1I,BAIAP3,CACNA2D2,HOMER3,WHRN,CSF1R,ARHGEF10,RIMS2,DAPK3,ZNF589,AGAP2,USP19,MAP4,NELL2,NNAT,CNOT4,NPR2,RETREG1,NLE1,PTH1R,C1orf54,ZNF493,COA1,ARHGAP26,SZT2,CRTC1,CABIN1,HIRA,ZBTB14" Drug 5214_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,BIN1,PLA2G4C,ATP6V0A1,CA4,RUNX1T1,LHX2,EPS15L1,VCAN,RIMS2,CDON,MBNL2,MTSS1L,PIPOX,INPP5K,GLYR1,GRIK5,GSN,ICA1,KCNN1,MBD1,TAGLN3,PCDH8,CEP41,CRTAC1,SH3BP2,SH3GL3,SLC2A5,ZKSCAN3,SNCA,KDM4C,SYN2,EXOC7,CHST5,AMACR,FAM155A,XRCC4" Drug 1748_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AMT,PKP4,ARNTL,ATP2A2,IQCK,AKAP6,SEC31B,GIT2,FCGRT,PCYOX1,SMC2,ERAP1,TMEM8B,KCNMB4,NXPH3,LSS,MIA2,NACA,SLC11A2,PDE4B,CCSER2,GPSM2,LRP12,MBOAT7,SAMD9,RGS12,FBXW7,AMBRA1,ZKSCAN3,ZMAT3,TK2,PARD3,WBP2,UCHL1,VSNL1,REEP1,RNF170" Drug 452_DN "indomethacin, USP; Down 200; 100uM; PC3; HG-U133A" Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "CDC42BPA,ANK2,SEMA7A,APBA2,GAS7,ARNTL,ATP2B2,N4BP2L1,HAP1,SCARB1,CHGB,NRG2,RIMS2,HS3ST2,EDNRA,RASL10A,OGA,DISC1,PRRC2B,GPR37,NXPH3,VSIG4,ICA1,LYRM9,NCF2,NELL2,NPTX1,PALM,ENPP2,NLE1,ACSM5,RET,ZNF821,ARHGEF40,FNBP1,SPART,VSNL1" Drug 6508_UP Isradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AK2,BEGAIN,APBB2,MARK4,CLGN,QKI,CNTN1,IPCEF1,USP6NL,RASSF2,EDNRB,MBNL2,VPS13B,ANKMY1,FGF13,FGFR1,AGAP2,ANKFY1,OGA,RUNDC3A,TXNL4A,HAS2,KPNA5,MAN2A2,MBD1,MYCN,MYT1,PCDH8,RGS4,TCP11L1,PDZD2,CEP68,PLCB1,CABIN1,TRPM2,SLC30A3,SEMA3B" Drug 1525_DN Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AK2,GAS7,FAM131A,SLC4A4,CBFA2T2,FOXN3,PLEKHB1,RAB28,SULT4A1,LRIG1,PDE4DIP,DCAF8,GIT2,TMCC2,DTNA,CNNM1,CDKL3,B4GALNT1,ZNF276,SLC2A6,MATK,SLC25A23,NKAIN1,ZNF821,FBXO11,TMCC1,ELOVL4,PLCB1,ARC,FBXW11,KIAA0930,AP4E1,ZNF74,SPHK2,REEP1,FTSJ1,ST7" Drug 6192_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADORA1,SYT13,TRMT9B,AMH,RASL11B,SLC4A4,MYOM1,CACNB4,SLIT2,CDC42BPB,CRY2,CSF1,KLHL3,EDNRA,HEYL,OPTN,MTSS1L,APC2,FHL1,HPCAL4,GPR75,GRIK5,MAP2,OPRL1,PFKFB2,ELOVL2,KLHL11,SH3BGR,SH3BP2,FRMPD1,ASAP3,PHLDB1,TK2,TNS1,TRIO,ZBTB38,SLC17A7" Drug 4363_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "C1QTNF1,BIN1,SEMA7A,PRX,SCAPER,SULT4A1,DGKG,ANKMY1,REEP2,FYB1,ERAP1,ALDH1L1,GPR162,RUNDC3A,KCNB1,KIF5A,MGAT3,ADAM22,TAGLN3,MYT1,CNOT4,NTRK3,PLCB2,PPP2R2B,PRKCB,GDPD2,CCDC40,SATB1,MRAS,MYH15,ZC4H2,TACR1,WSCD1,R3HDM1,LAT2,LAMP5,PLSCR4" Drug 1430_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; HL60; HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,CDC14B,CAST,CLCN3,AATK,PPP1R16B,C2CD2L,IRAK4,MRNIP,GAA,PRRC2B,FAM107A,NACA,OCRL,PALM,ENPP2,PLCD1,MAPK3,CNNM2,DEF8,TMEM260,C1orf54,CCDC25,ZNF671,FAM214B,ELMO2,MAPKBP1,FAM208A,MGRN1,TCF4,THRA,KAT6B,TNS1,PLPPR2,TRIM9,VPS35L,AAAS" Drug 2815_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AMPD3,CDC42BPA,GAS7,APOC1,CDK10,ARHGDIG,MARK4,CFAP410,LHX2,SULT4A1,CNTN1,CSNK1E,SIPA1L1,JAKMIP2,DTNA,ENO2,CSPG5,DISC1,AHDC1,GLYR1,HNMT,DHX35,TJAP1,SMAD1,MITF,MX1,NEK1,SMIM7,POLG,MINDY2,PRPH,ELOVL2,CEP97,SH3BP2,FAM214B,R3HDM1,KCNK12" Drug 7233_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SLC4A4,NRP2,SCAPER,HAP1,ARHGEF2,SLIT2,TPP1,COL9A3,CSF1R,INTS1,HIPK3,TPK1,USP19,GLYR1,TDRKH,GRM8,ELOVL5,ITPKB,KCNH2,LSS,MAN2A2,MSI1,NF1,NTRK2,RAD51D,FAM184A,RGS12,FRMPD1,SYBU,SLC2A5,ZC3H13,TPM1,TPM2,TRIO,PLPPR2,LAT2,FAM13C" Drug 6096_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADRA1D,LTBP4,BEGAIN,KSR1,MYRF,KALRN,EPS15L1,NCOR2,ARHGEF10,SEC14L5,EDN1,SPEG,FGFR1,FYB1,ZNF44,GAD1,PRUNE2,ADAMTS13,SHISAL1,C2orf72,TJAP1,KIF5A,MAP4,AFDN,TAGLN3,P2RY1,RGS12,KLHL11,SH3BP2,PEG10,SPTAN1,SPTB,CLSTN2,SYT5,KIAA1107,SLC30A3,SLC17A7" Drug 6560_UP Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ACTN1,ARRB2,CDH2,PLEKHB1,BAG4,VCAN,CTH,DCAF8,GIT2,DBN1,DBT,PHC2,MRNIP,COQ7,FHL1,FAM49B,STON1,PADI2,TAGLN3,NFYA,OCRL,PCDH9,SAMD9,BCAS3,PTN,ZCWPW1,TCP11L1,RBM34,ARHGAP26,PCDHA5,BHLHB9,HIRA,LAT2,UPF3A,EPM2A,ST7,PHTF2" Drug 2623_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APAF1,APBB2,CFLAR,KYAT1,SLC4A8,ABCG1,DBT,DCTN1,LYPD1,SGSM2,FHL1,AGAP2,MSL3,GPD2,GPER1,KHK,LIG4,PLEC,PRKACB,RAD51D,ZCWPW1,ZDHHC14,CCDC25,RPS6KA2,SBF1,ZNF821,SGK1,ABLIM3,PDZRN3,ASTN2,TACC1,TK2,PLPPR2,LMF1,XRCC4,ZNF23,MPPE1" Drug 6301_DN Clopamide [636-54-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MTUS1,EP400,MTMR2,SOCS6,BAG4,USP6NL,C2CD2L,ERCC2,SPEG,B4GALNT1,ERAP1,GNG4,SLC2A6,AGBL5,MEIS1,TAGLN3,ZNF862,SLC11A2,PLCD1,MINDY2,PPP3CC,NDUFS7,PTK2,FAT4,GAL3ST4,SBF1,ASAP3,ZBTB43,SS18,ARHGEF9,PLCB1,IQCE,CBX5,PARD3,TNS1,XRCC4,MPPE1" Drug 762_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADD1,SYT13,CDC42BPA,APBB2,NCOA1,NRP2,BAIAP3,LARGE1,DRP2,VPS13B,EPB41L2,STX2,ZNF589,OLFM1,FGFR1,USP19,ZNF276,CACFD1,L1CAM,GIT1,NEK1,NNAT,NTRK3,PDPK1,CCDC40,RAP1GDS1,ZNF671,RXRA,GLT8D1,ERC1,CEP68,EXOC7,DMXL2,CHST5,ZNF24,MAP3K12,MPPE1" Drug 2176_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SYN3,BIN1,BMP7,GYG2,CFAP410,CBFA2T2,DLGAP2,TAOK2,SLIT2,COL9A3,CSNK1E,SIPA1L1,PDE4DIP,DZIP3,SPOCK2,MFAP3L,MBNL2,AGAP2,IQCG,SIGLEC8,GATM,ADAM28,KIFC3,MAP4,MEF2C,ADAM22,MYCN,CNOT4,SLC25A23,PPP2R2B,MAPK7,BEND5,SYN2,XRCC4,ZBTB38,SLC17A7,KCNAB1" Drug 4796_DN Colistin sulfate [1264-72-8]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,EP400,APBB2,APOC1,SCAPER,CAMK2G,PDE4DIP,HDAC4,GIT2,JAKMIP2,DTNA,ZNF276,ELOVL5,IL6R,MAP4,MITF,MPP2,SLC11A2,PLEC,SMIM7,PPP2R2B,ELOVL2,RPS6KA2,SBF1,ZNF821,FAM214B,SPTAN1,IQSEC2,TROVE2,ARHGEF9,VPS13A,KIAA0930,PCDHGA10,THRA,LMF1,PCBP4,SMIM8" Drug 7083_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BRAP,AK2,ALCAM,PPFIA3,BMP7,GYG2,BAIAP3,CFAP410,MAGI1,PDE4DIP,DOCK4,OPTN,FGFR1,AGAP2,EFCAB2,INPP5K,GPER1,LYRM9,PDPK1,RETREG1,KCTD15,PRKAR1B,FAM184A,GTDC1,FBXW7,RPS6KA2,SUPT20H,FAM214B,ARHGAP26,SPTAN1,CLSTN2,THSD1,DIP2A,EXOC7,CABIN1,HIRA,ITM2C" Drug 1970_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SEMA4G,FOXN3,CLTB,SMARCAL1,SPATA2,NR1D2,DTNA,SUCO,SEC23B,DBF4,KCNN2,IPO5,MITF,GIT1,MYO5A,NEFH,PFKFB3,PPM1B,MAPK9,C1orf109,RAP1GDS1,RDX,EXD2,SLC2A5,ELMO2,MAPKBP1,RGL1,DMXL2,SIRT1,TK2,TMPO,R3HDM1,PIK3R5,TSN,ZBTB14,ZNF142,ZNF184" Drug 5108_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "GAS7,CDK13,KSR1,EPS15L1,SULT4A1,AKAP5,ENTPD4,CRMP1,ABCG1,USP6NL,ING4,COQ7,RASGRP2,SPEG,FAM49B,DISC1,LAMA2,MIA2,CNOT4,MINDY2,GRAMD1C,SNRK,ZSCAN2,TCP11L1,RPS6KA2,ZNF821,DZIP1,SLC4A3,KDM4C,ZBTB43,ZNF34,R3HDM1,TNS1,TPM2,VIPR2,LAT2,HPS4" Drug 4062_DN Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BIN1,APBB2,SEMA4G,PPP4R4,ADAM23,NRP2,CACNA1I,MYRF,FOXN3,RAB26,WHRN,NCOR2,PPP6R2,DAPK3,MTSS1L,ERCC2,FGFR1,GPER1,SHISAL1,JAK2,KIFC3,MATN3,MYT1,CNOT4,PIK3R1,RETREG1,PID1,ZFP30,ANKRD6,PPP4R3A,UNC5B,CAMTA2,SYN2,ASTN2,EXOC7,VIPR2,LAT2" Drug 2489_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,MTUS1,C1QTNF3,BIN1,GAS7,APOC1,CDK10,SCAPER,CACNA1A,RAB33A,HOMER3,CNTN1,ABCG1,SLITRK5,ING4,TUBD1,PIPOX,PTK2B,ZNF44,SLC11A2,SETD4,CCSER2,PLCD1,SLC25A23,PILRA,DEF8,CNTLN,PTN,SEC14L1,SLC11A1,TROVE2,CRTC1,TPM1,ELP5,CLIP2,ACTR3B,SENP7" Drug 7515_UP CP-645525-01 [287190-82-3]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABHD6,NME5,DNAH17,KIF1A,CFLAR,FUBP1,CBFA2T2,EPS15L1,DAPK3,SPOCK3,CDON,TOM1,OPTN,PLXNC1,REEP2,FGFR1,MSL3,LPAR4,SYNPO,MYO7A,ZNF862,OCRL,PPP5C,MAPK7,PTCH1,ZSCAN2,RPS6KA2,CLIP1,LIMS2,FAM214B,NMNAT2,TBL1X,TRIM2,BEX4,PARD3,ZNF184,RNF146" Drug 4991_DN Glipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG3,NME5,OGT,SHROOM2,BCL7A,CFLAR,MAGI1,QKI,ENTPD4,NCOR1,PDE4DIP,PARD6A,SGSM2,DTNA,TOM1,FCF1,ACSL4,FER,SRCAP,ARFIP1,MAN2A2,MBP,CNOT4,RETREG1,PRKAB2,TMEM231,FAM184A,PPP4R3A,LIMCH1,ZHX3,SS18,TTBK2,TMPO,XRCC4,ZNF74,SMIM8,RNF146" Drug 3876_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "CDC42BPA,GAS7,APLP1,SLC2A11,BCL7A,CFLAR,CA12,MAGI1,BAG4,NCOR2,DZIP3,MAMLD1,ING4,HSD17B14,ERCC2,KAT8,ZNF589,CGREF1,SRCAP,AHDC1,FERMT2,GPER1,GRM8,IL6R,MAP2,KITLG,MMP17,RAD51D,LIMCH1,MAPKBP1,ZNF423,IQSEC2,CEP68,HEY1,LMF1,MAP3K12,EPM2A" Drug 5790_DN Tropine [120-29-6]; Down 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,APC,PDE8B,MTMR3,CLTB,AKAP7,CSF1,CSF1R,GPRASP1,SCML2,POMT1,PCDH17,GNG4,CNTRL,SHISAL1,TJAP1,INPP5B,MMP16,GIT1,LYRM9,ZNF862,NF1,FAM184A,BEND5,SBF1,ATXN7,ASAP3,BTBD7,KDM4C,SPTAN1,CEP68,SYT1,KIAA0930,TPM2,HIRA,FAM155A,TRIM9" Drug 3972_UP Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "C1QTNF1,BIN1,GYG2,SEPT7,RAB33A,STOML1,CABP1,CRY2,VCAN,ARHGEF4,CHRDL1,SNX29,EDNRA,HSD17B14,EPHB1,ERCC2,PTK2B,DLC1,GABRG2,LYVE1,STMN2,SOX21,NXPH3,ITGAM,KCNJ5,AFDN,PLCB2,ZFHX4,ST6GAL1,SLC11A1,CXXC4,ADGRL3,TCF4,PCDHGB6,PIK3R5,UCHL1,NLRP3" Drug 4762_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,AP2A2,CDC14B,CAMK2B,ARHGEF1,LHX2,WHRN,NCOR2,ARHGEF10,CNTNAP2,GREB1,RIMS2,PPP6R2,DAPK3,CNNM1,HSD17B14,FGFR3,ZNF862,NPTX1,OGG1,PDE4A,SERPINI1,PRKAR1B,ELOVL2,CEP97,ZDHHC14,RET,RIC8B,ZNF821,SMARCD3,DOP1A,FNBP1,LHPP,JMJD6,ARC,DMXL2,UBTF" Drug 2849_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ADCY6,AP2A2,KIAA1324,C1QTNF3,CDC42BPA,APAF1,APBB2,BCAS1,ARHGDIG,PDE8B,ALDH7A1,KYAT1,CSF1,PPP6R2,DOCK4,SPOCK2,ELN,CDKL3,SCARA3,GNAO1,TDRKH,ELOVL5,MMP16,MSI1,CNOT4,PPARA,PPP2R2B,PRKAR1B,MAPK10,PTN,CRTAC1,CARF,SOX3,TK2,REEP1,GDPD5" Drug 4757_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SRPX,BIN1,CDC42BPA,FAM131A,PPFIA3,ALDH7A1,ST3GAL5,CFAP410,CA4,ARHGEF1,LHX2,WHRN,ABI3BP,NCOR2,PDE4DIP,PPP6R2,C2CD2L,EIF4G2,AFF2,ATXN2L,IL6ST,MEF2C,NFYA,NNAT,RETREG1,SAMD9,RIPOR1,TMEM231,KCTD17,EPN2,LHPP,CLSTN2,PLCB1,ARC,SMG6,KIAA0930,TK2" Drug 3450_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABHD6,NDRG3,OGT,BCAS1,MPDZ,KYAT1,B4GALT6,BAG4,FAM169A,RUBCN,MFAP3L,TOM1,TSPAN5,HIPK3,EIF4G2,ZNF589,ATP2C1,B4GALNT1,GLUL,MAPT,MIA2,ADAM22,NPR2,SLC25A23,CEP97,FBXO11,FNDC3A,ABLIM3,ZKSCAN3,LIMCH1,SPART,TMPO,XRCC4,MAP3K12,PHTF2,RNF170,AAAS" Drug 5286_DN Dichlorphenamide [120-97-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APC,CDC14B,ARHGEF7,CNOT8,RAB28,PLAA,FAM169A,PPP6R2,DAPK3,C2CD2L,SGSM2,TSPAN5,CELSR3,GPHN,CDKL3,FAM49B,CGREF1,INPP5K,MSL3,RNFT2,HSF2,MBD1,NF1,NPR2,SLC11A2,OCRL,PRKAR1B,CEP97,SGK1,EPN2,SIRT2,ERC1,LHPP,EXOC7,VIPR2,MAP3K12,RNF146" Drug 4351_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "CDK13,MARK4,N4BP2L1,CFLAR,BMPR1B,RUNX1T1,CBFA2T2,CBARP,SULT4A1,CNTN1,CNTNAP2,SPOCK2,APC2,REEP2,NSG1,GPER1,IGF1,MAPT,MARK1,MBP,TAGLN3,MX1,PRKCB,MASP1,RELN,KLHDC8A,MRAS,SLC14A1,PEG10,ZC3H13,RBM26,SLC35G2,TRIO,UCHL1,MKRN3,SLC17A7,DPF3" Drug 5827_UP Mifepristone [84371-65-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SEMA7A,SEMA4G,SLC4A4,KIF1A,MYRF,BAIAP3,CACNA2D2,NRXN3,RAB26,IQCK,SNPH,FCF1,KAT8,FER,TRMO,CGREF1,KCNB1,KIFC3,GIT1,PALM,SERPINI1,PPP2R2B,DCHS2,RFX2,RGS12,FBXW7,RYR3,SUPT20H,CCDC88A,LIMCH1,TMCC1,ZBTB43,TIMP4,BEX4,TRO,TFIP11,KCNAB1" Drug 7313_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADCY6,ALK,KCNAB2,SEMA4G,TAOK2,LY86,HOMER3,CPS1,ARHGEF10,HDAC9,DTNA,ADAMTS13,GRM8,SHISAL1,TJAP1,KHK,LAMA2,NF1,NOVA2,PDE4D,MINDY2,TMEM231,KCTD17,SBF1,FRMPD1,ZSWIM8,ARHGAP26,SPTB,PBLD,THSD1,SYT1,EXOC7,SLC35G2,TIAM1,OSBP2,VLDLR,WIPF1" Drug 2727_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADORA1,APBB2,PPFIA3,BMP7,CACNB4,CACNA2D2,STOML1,NCOR2,DAPK3,DBT,DMPK,EDIL3,DLC1,HPCAL4,CSPG5,GFRA2,STMN2,SYNPO,KIF5A,NTRK2,OXTR,PDE1C,LRRN3,CEP41,PKNOX2,SNCA,DOK5,SOX15,PEG10,IQSEC2,PLCB1,ASTN2,IQCE,FAM189A1,SLC19A3,SPHK2,SLC17A7" Drug 3023_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MTUS1,APAF1,ADAM15,FUBP1,CACNB4,TPP1,FAM149A,ARHGEF4,RUBCN,BRINP1,B3GAT3,KIAA0753,VPS13B,AGAP2,ADAM28,GNG4,LILRA2,PADI2,ATXN2L,TJAP1,KCNJ5,MAP4,TAGLN3,NLE1,POU6F1,PTCH1,TMEM231,GALNT10,ANKRD6,EPN2,CCDC88A,ZNF415,PCDHGB6,TPM1,CDK20,KCNK12,SH3GLB2" Drug 6440_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BIN1,AMT,BCL7A,SCAPER,KRIT1,CBFA2T2,CRY2,ABCG1,DMPK,ANKMY1,ZNF589,SCARA3,GRIK5,CACFD1,IFI16,TM6SF1,CDK18,SERPINI1,SNRK,SUGCT,RPS6KA2,SH3BGR,KIF16B,IQSEC2,PLCB1,SYT1,EXOC7,KIAA1107,TRIM2,HEY1,CHST5,ZNF74,SPHK2,EVI5,HPS4,URM1,DPF3" Drug 5213_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,ADORA1,C1QTNF1,SEMA7A,APBB2,MARK4,CDH2,ARHGAP33,CLGN,STOML1,LY86,ENTPD4,CTH,RUSC2,ZNF589,FGF13,FGFR1,BAIAP2,FHL1,SIGLEC8,RUNDC3A,POLL,GNAO1,HLF,KHK,ZNF862,NECAB2,PPP5C,RGS12,PNMA8A,ZNF821,LIMCH1,DOK5,HECW1,ARC,MCF2L,CDK20" Drug 2817_UP Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MARK4,SLC4A4,ATP2A2,MYRF,SEPT7,ARHGAP33,RCBTB2,AKAP7,RCHY1,NECTIN3,PDE4DIP,TMCC2,EXOG,FRY,PIPOX,FGFR3,GFER,ELOVL5,TJAP1,KCNF1,AFDN,NF1,PDE1C,ELOVL2,TCP11L1,RPS6KA2,KCNIP1,SAFB,SH3BP2,NLGN1,PKNOX2,SLC9A5,CXXC4,KIF13A,ATP10B,SPHK2,ST7" Drug 6453_DN Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SEMA6A,TRMT9B,AMPD3,CDK10,PLA2G4C,MARK4,BAIAP3,ENTPD4,SH2B1,GIT2,EGFR,PLXNC1,COQ7,FHL1,CNTRL,CACFD1,IPO5,LMO2,MAP4,LYRM9,NELL2,NFYA,NPR2,P2RY1,PLXNB1,PRODH,PTN,ZSCAN32,KHDRBS2,ZNF821,ZHX3,LHPP,ARHGEF9,ARC,HEY1,LMF1,URM1" Drug 4080_DN Cefadroxil [50370-12-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABR,NME5,APBB2,SEMA4G,MARK4,ATP2A2,ALDH7A1,ADAM23,C5,TAOK2,RAB26,CNTFR,ENTPD4,CSF1,VCAN,DZIP3,SNPH,MFAP3L,PLPPR4,MTSS1L,ZNF862,PIK3R1,PPP5C,GRAMD1C,TMEM231,KIRREL1,AMBRA1,DZIP1,SLC4A3,TMCC1,UNC5B,ASTN2,R3HDM1,TPM2,HIRA,ZBTB14,MAP3K12" Drug 7279_UP Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADCY6,MTUS1,CASK,ARRB2,MARCH3,CFLAR,RAB29,RAB28,ENTPD4,GIT2,LYPD1,EDIL3,IRAK4,ERCC2,FGF1,TRMO,ERAP1,SYT17,FAM69A,INPP5B,KIF2A,PIK3R1,PTPN13,TMEM231,ROGDI,ZDHHC14,WDR37,SIRT2,SS18,DIP2A,CABIN1,ZBTB38,EMSY,UBE3B,KAT6A,PHTF2,AAAS" Drug 4785_DN Idoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,MAP4K3,CFLAR,FUBP1,SCAPER,KYAT1,LRIG1,PDE4DIP,DCAF8,DCTN1,MFAP3L,MRNIP,EZH1,FHL1,GAD1,MSL3,GNG4,CACFD1,DHX35,NFYA,PDE4A,PLEC,FSD1,MINDY2,TMEM231,SH3BP2,AMBRA1,EPN2,BTBD7,LIMCH1,PDZRN3,ZHX3,CAMTA2,ASTN2,ANKRD12,VAV1,SMIM8" Drug 4654_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADCY6,MTMR2,SOCS6,B4GALT6,RAB28,SLC4A8,BAG4,VCAN,DAPK3,BRINP1,FAM13A,ING4,ETV1,SEMA4D,SYT17,FAM69A,LIG4,PDE4B,PFKFB2,PLCD1,PPARA,PRKAR1B,PTK2,ZSCAN2,KHDRBS2,FBXW7,EPN2,KDM4B,ARHGAP26,SPTAN1,TROVE2,CAMTA2,SS18,TK2,TMPO,UBTF,PHTF2" Drug 1510_DN Erythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ARRB1,CFLAR,SPAG9,CBFA2T2,PLEKHB1,SULT4A1,AKAP7,SH2B1,CRY2,DZIP3,DCAF8,AHDC1,GLYR1,GPD2,GRB10,BTN2A1,ADAM22,LYRM9,RETREG1,PPP3CC,TMEM104,NEK11,TCP11L1,SMARCD3,ZHX3,UNC5B,ZBTB43,CEP68,ANKRD12,TBL1X,SIN3B,TNS2,CRTC1,VGF,KLC2,EPM2A,GAN" Drug 7361_DN 3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,AMPD3,BCAS1,PPFIA3,NUMB,CAMK2B,CACNA2D2,RIMS2,DCAF4,GIT2,MED12,CDON,FGFR1,INPP5K,MSL3,ITPKB,KCNF1,KCNH2,MAPT,KITLG,ADAM22,ZNF862,STRN3,PRKAR1B,NKAIN1,CEP97,RNASEL,EMID1,ZFP30,SIRT2,TRIM2,TNS2,CRTC1,PCDHA6,TPM1,REEP1,KCNAB1" Drug 1844_DN Panthenol (D) [81-13-0]; Down 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,C1QTNF3,APAF1,ARHGEF1,ARHGAP33,EPS15L1,TMEM184B,HOMER3,CREM,SH2B1,CRY2,PPP6R2,DCAF8,ZNF337,SGSM2,DTNA,STX2,ANKMY1,ZNF589,DCTN2,SEPT9,USP19,CRCP,MAN1B1,ZNF862,PLCB2,PLTP,MAPK3,CCDC25,AMBRA1,SLC11A1,SS18,EXOC7,HSPBP1,ZKSCAN5,UBTF,PLPPR2" Drug 6525_DN Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABR,BIN1,OGT,SEMA4G,BACH1,SPAG9,DZIP3,DAPK3,DBT,JAKMIP2,SUGP2,COQ7,MALT1,MSL3,GNG4,STON1,GRIK5,TM6SF1,ZNF862,POLG,PPP5C,PRODH,TMEM104,EMID1,KDM4C,TROVE2,SS18,NXT2,KANK1,CHST8,CABIN1,VAV1,VGF,ZNF24,ZFAND5,PHTF2,RNF146" Drug 4412_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ALK,BIN1,GAS7,CDK13,ATP2B2,KSR1,BAIAP3,CACNA2D1,SEPT7,CACNA2D2,SULT4A1,CNR1,WHRN,NCOR2,DBT,ZNF589,FGFR1,LILRA2,GRIK5,CEP41,KLHDC8A,PLPPR3,ASAP3,ST6GAL1,SLC2A5,LIMCH1,PEG10,TCF4,PCDHA6,SLC35G2,TMEM121,TK2,TNS1,XRCC4,MKRN3,SLC30A3,KCNAB1" Drug 3764_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BRAP,ALK,AMPD3,APC,SLC4A4,ADAM23,ARHGAP22,LY86,CREM,HAPLN1,DTNA,EGFR,FGF1,DCTN2,CINP,DENND2A,SEPT9,TDRKH,MN1,NF1,CNOT4,RETREG1,CNNM2,WDR25,TCP11L1,SCN8A,BTBD7,SNCA,ARHGAP26,ATP10B,TBCEL,GPR161,TIAM1,TNS1,TPM1,VLDLR,TRIM9" Drug 2013_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AMT,ARNTL,RIPK1,CLDN10,ARHGAP33,TAOK2,CNTN1,CTH,DNM1,SLC12A6,FCGRT,TRMO,CAMKK2,CGREF1,FYB1,SRCAP,RUNDC3A,GPR12,HSF2,IL6R,LSS,MYT1,NF1,NUCB2,PLEC,RETREG2,MBOAT7,SNRK,AMBRA1,CHD9,SLC11A1,SLC22A4,CEP68,SYN2,PDLIM2,TFIP11,ACTR3B" Drug 7475_UP Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADORA1,CACNA1A,HAP1,CAMK2B,CRY2,TBC1D5,DBN1,DNM1,DRP2,DTNA,ENO2,ERCC2,PRELID3A,DISC1,MALT1,ELOVL5,ADAM22,NF1,NPTX1,PDE1C,PLXNB1,WDR25,PTCH1,PTPRN2,RIPOR1,KCTD17,GSTCD,SEC14L1,SH3GL3,ASAP3,SNCA,ZHX3,VPS13A,COBL,ASTN2,EXOC7,SPHK2" Drug 2910_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,ADAM15,BCL7A,C5,SLC25A14,KYAT1,TPP1,IQCK,PDE4DIP,GIT2,PCOLCE2,TUBD1,SCML2,ST3GAL6,COPS8,AGFG1,DHX35,MAP4,MITF,SLC11A2,STRN3,PILRA,PTPRN2,ZCWPW1,TCP11L1,HSPA4L,DHX30,COA1,TSPYL2,SYNE1,AP4E1,PIK3R5,ZKSCAN5,LAMP5,ZNF225,MAP3K12,NLRP3" Drug 2760_UP Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ALCAM,BIN1,PPFIA3,RGS20,ATP2A2,CACNA1I,CFAP410,KALRN,SEPT7,ARHGAP33,TAOK2,HOMER3,CAMKK2,GCNT2,HNMT,MAP4,MMP17,CDK18,PPP5C,ELOVL2,CCDC40,C1orf54,RPS6KA2,RASA3,FRMPD1,EPN2,PKNOX2,PEG10,ARC,CRTC1,HEY1,PARD3,HIRA,VIPR2,XRCC4,HPS4" Drug 4779_UP Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "PPP4R4,MTMR2,CAMK2G,RCBTB2,STOML1,COL9A3,SOCS5,DCAF4,SPOCK3,EGR3,ING4,GPHN,STX2,DENND4A,ARMCX1,ZNF589,IQCG,ERAP1,VSIG4,KCNN2,LIG4,MBNL1,ADAM22,NF1,NPY,SLC25A23,CPEB3,PPP4R3A,PEG10,NXT2,WSCD1,TRIM2,BEX4,CHST5,VLDLR,WIPF1,CLDND1" Drug 5495_DN Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASPHD1,AK2,BCAS1,CASK,ARNTL,NCOA1,ATP2A2,SCARB1,COL4A5,PDE4DIP,GIT2,DCTN1,RCAN1,DTNA,DLC1,GAD1,POLL,GNG4,MYO6,PDE4B,SLC25A23,PPP5C,MRPS18A,SAFB,SGK1,PEX26,CDK5RAP2,SPTAN1,STX1A,EXOC7,FBXW11,VGF,XRCC4,ZNF74,REEP1,HPS4,ST7" Drug 459_DN copper(II) sulfate pentahydrate; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ADCY6,APBA2,NCOA1,ATP6V0A1,P2RX6,LY86,GIT2,RCAN1,OPTN,SUGP2,DLC1,HPCAL4,BTN2A1,SOX21,RASSF8,ADAM22,CNOT4,PLCD1,PPM1B,VPS13C,SUSD4,RET,ZC3H14,CASC3,SLC2A5,SMARCC2,ZHX3,ZC3H13,SPART,CEP68,PLCB1,EXOC7,TBL1X,TNS2,WIPF1,FIP1L1" Drug 7332_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AP2A2,LTBP4,ALK,PPP4R4,CAMK2G,USP2,HOMER3,JAKMIP2,EGFR,DLC1,ZNF589,FGFR1,IQCG,SEPT9,SRCAP,RUNDC3A,POLL,STON1,GRM8,SOX21,TJAP1,IL6ST,KCNN1,NF1,NPTX1,NLE1,ZSCAN32,RGS12,ZFHX4,ZNF821,SH3GL3,ABLIM3,STX1A,ADGRL3,RPGRIP1L,AP4E1,CHST5" Drug 7474_DN Fenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APC,PPFIA3,CDK10,MADD,MARCH3,BMP7,LARGE1,EPS15L1,TMEM184B,ARMC8,ARHGEF10,CSNK1E,DZIP3,DCAF8,DBT,ANKFY1,CINP,NFYA,CNOT4,SETD4,PLEC,ELOVL2,PTPRE,QDPR,FERMT1,FNDC3A,ABLIM3,CDK5RAP2,MAPKBP1,ARHGAP26,PHLDB1,SIK3,TIAM1,NPL,METTL3,HPS4,GAN" Drug 6395_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADCY6,GAS7,APOC1,MYOM1,ADGRB3,CFLAR,HAP1,ARHGEF6,CPS1,HAPLN1,PPP1R16B,HS3ST2,VPS13B,ST3GAL6,FGFR1,PDLIM5,RASL10A,CHL1,SEPT9,LILRB4,HLF,ADAM22,SAMD14,MYO7A,SEPT4,SAMD9,PTN,MARCH1,KHDRBS2,UNC5B,ATP10B,SYT5,CUX2,SLC35G2,MKRN3,PRDM10,AP3B2" Drug 7220_UP Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MARK4,SLC4A4,ADGRB1,SCAPER,PLAA,SULT4A1,SNPH,GIT2,EGR3,HSD17B14,ERBB2,FGFR3,OGA,FYB1,RUNDC3A,ELOVL5,MSI1,ZNF862,NF1,ENPP2,NLE1,WDR25,ZSCAN2,ZDHHC14,KCNIP1,MRAS,FRMPD1,SYBU,BTBD7,ATP10B,WSCD1,TRIM2,TK2,TPM1,AMACR,FAM155A,UBE3A" Drug 4120_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AMPD3,ARRB1,CDK13,N4BP2L1,USP2,AKAP7,WHRN,NCOR2,RGS6,CNTNAP2,RIMS2,DAPK1,DMPK,EDNRA,TENM1,SPEG,GAD1,FAM107A,ATXN2L,SHISAL1,MMP17,ADAM22,MX1,PDE1C,PFKFB2,LRP12,PPARA,KCTD17,ZFP2,CCDC88A,SLC11A1,PEG10,ATP10B,KIAA1107,TPM1,SLC30A3,AP3B2" Drug 2488_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADD2,AGT,ARHGDIG,KSR1,EPS15L1,SULT4A1,RAB26,COL9A3,CREM,DAPK3,C2CD2L,RASGRP2,MTSS1L,CAMKK2,GPR75,PCLO,RASSF8,KIFC3,MMP16,NEFM,CCSER2,PRKAR1B,RFX2,KCNIP1,SNCA,ARHGAP26,SPTB,DDN,NFASC,PLCB1,TAL1,DOCK9,TK2,KAT6B,FLRT2,SLC17A7,KAT6A" Drug 6505_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABR,BIN1,AMT,APC,FAM131A,PPFIA3,CDC14B,SLC4A4,CFLAR,BAG4,ZNF337,DBN1,MED12,CNNM1,EGFR,COQ7,PRKAG2,SEMA4D,INPP5K,FAM69A,KCNF1,LYRM9,ZNF862,OCRL,PCDH9,RGS12,TRAPPC13,ABLIM3,SLC6A8,BTBD7,RBM34,TROVE2,SS18,EXOC7,CLDND1,ZNF74,ACTR3B" Drug 3472_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABR,PPFIA3,ATP6V0A1,PLAA,TPP1,ARMC8,DTNA,EDNRA,FAM198B,KAT8,BAIAP2,SYT17,INPP5K,GLYR1,GLUL,CNTRL,DHX35,INPP5B,MIA2,KITLG,MPP2,RETREG2,PTCH1,RAD51D,SBF1,GALNT10,AMBRA1,ELMO2,DOP1A,TSPYL2,IQCE,TRIM2,BEX4,PARD3,KCNK12,ZNF74,MPPE1" Drug 6202_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AGT,AMT,ANK2,APAF1,CASK,NUMB,KIF1A,SLC25A14,CAPN3,CARS,TAOK2,CREM,CTH,TBC1D5,RUSC2,PCOLCE2,TUBD1,COQ7,FYN,SEPT9,INPP5K,TJAP1,IL6ST,SLC11A2,TRHDE,TMEM104,C1orf109,DDN,EXOC7,TPM1,TSC2,PLPPR2,VIPR2,VLDLR,LAT2,XRCC4,KCNAB1" Drug 6083_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABHD6,AP2A2,NME5,C1QTNF3,BCAS1,SLC4A4,ATP6V0A1,GYG2,CA4,HAP1,CBFA2T2,FOXN3,QKI,AKAP7,SIPA1L1,PDE4DIP,RIMS2,MAML1,DTNA,C3orf18,FGF12,POLL,DHX35,INPP5B,KPNA5,ADAM22,MAPK7,PRODH,RGS3,SEMA6D,SMARCD3,KIF13A,UNC5B,SYN2,HEY1,TPM1,WIPF1" Drug 1340_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SEMA4G,CDK13,NUMB,C5,CA12,KRIT1,SCARB1,STOML1,HOMER3,ZNF337,TM9SF4,PDLIM5,ERAP1,HTATSF1,KCNMB4,GRIK5,MAP4,OGG1,MBOAT7,MAPK7,DEF8,CNTLN,PTCH1,ZNF331,FUZ,ANKRD6,FAM214B,BTBD7,SPTAN1,PBLD,DNMBP,CRTC1,TRPS1,XRCC4,ZBTB14,SLC17A7,UBE3B" Drug 4735_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG3,ADRA1D,TRMT9B,AMPD3,MADD,CAMK2G,TAOK2,SLIT2,RIMS2,SLC12A6,SUGP2,ZNF589,FGF12,FHL1,AFF2,HTATSF1,POLL,STON1,GRM8,KPNA5,MAP4,KITLG,MMP16,MSI1,ADAM22,ZNF862,MYT1,SERPINI1,MSANTD2,GSTCD,ZNF821,BTBD7,COA1,PCDHA5,TNS1,HIRA,HPS4" Drug 2138_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SYN3,ASIC1,FAM135A,ALK,DOC2A,BIN1,CDC42BPA,APOC1,N4BP2L1,ADGRB1,CACNA1I,AATK,RUSC2,TMCC2,REEP2,DLL3,TMEM8B,SIGLEC8,ALDH1L1,ZNF276,GPER1,GRIK5,RASSF8,PADI2,HNMT,KCNN1,LAMA2,ZNF862,PTPRN2,NEK11,FRMPD1,CDK19,ST5,PHLDB1,GPR161,VSNL1,SPHK2" Drug 4621_UP Niridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LTBP4,KIF1A,GYG2,CACNA1G,THSD7A,SOCS6,WHRN,PDE4DIP,C2CD2L,PLPPR4,DRP2,EDNRA,AASS,EIF5,EPB41,FAM198B,ERAP1,GNG4,LPAR4,GRM2,LSS,TAGLN3,NF1,MAPK4,RASGRF1,GAL3ST4,NEK11,SEMA6D,NLGN1,ANKRD6,PPP4R3A,ARHGAP26,PHLDB1,ARC,VGF,VIPR2,HRASLS" Drug 1503_DN Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG3,APOC1,CDK10,ARRB1,ARRB2,KIF1A,CAMK2B,B4GALT6,SH2B1,CSF1R,SLC12A6,DTNA,HIPK3,ING4,PCOLCE2,CDKL3,EZH1,INPP5K,GNG4,IL6ST,JAK2,MAP4,SCAMP5,ADAM22,NF1,POLG,PRPH,GSTCD,FNDC3A,BTBD7,KDM4B,ZNF423,CDK19,ZBTB43,SYT1,TRIO,HIRA" Drug 607_DN butein; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ANK2,GAS7,AQP6,CDK10,TBRG4,SLIT2,HINFP,AATK,PDE4DIP,DRP2,MRNIP,SRPK3,OLFM1,FGFR3,MALT1,RUNDC3A,GNG4,BTN2A1,IGF1,KHK,SMAD1,MMP17,GIT1,ADAM22,TREM2,RGS12,TCP11L1,KBTBD4,SMARCA4,PEG10,ATP10B,TROVE2,SEPT8,ANKRD12,THRA,WNT7A,SLC17A7" Drug 6239_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ACTN1,AK2,BIN1,CDK13,PDE8B,EIF4G3,LDLRAD4,CFAP410,CACNB4,LRRFIP1,PLAA,STOML1,QKI,HOMER3,BAG4,CREM,PDE4DIP,KIAA0586,SPOCK2,MPP6,GRM8,MAP4K5,IL6ST,INPP5B,NOVA2,PLTP,SAMD9,WDR25,KHDRBS2,KCNIP1,SH3BP2,ABLIM3,SS18,SATB2,GDPD5,HPS4,KAT6A" Drug 7199_DN Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APAF1,SYNJ2,USP2,FOXN3,SOCS6,TAOK2,PLAA,HOMER3,PICK1,GREB1,ZNF589,AFF2,OGA,INPP5K,HNMT,MAP4,SETD4,RETREG1,PPP3CC,TMEM104,RXRA,TMCC1,SPATA7,ZHX3,UNC5B,ZBTB43,SATB2,TNS2,BHLHB9,NR2C2,LMF1,ZNF24,HPS4,EPM2A,UBE3B,ACTR3B,GAN" Drug 2269_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "DDO,ARRB2,PDE8B,MARK4,ATP2B2,RGS11,NRP2,CD86,CBFA2T2,CSF1R,VCAN,CNTNAP2,SPOCK3,HSD17B14,ZNF589,RASL10A,NEU3,ALDH1L1,GRM2,IRF8,TJAP1,KCNQ3,MGAT3,SAMD9,CRTAC1,SLA,PDZD2,HECW1,SPART,ATP10B,ARC,EXOC7,ADGRL3,WSCD1,PCDHA5,PLSCR4,SMIM8" Drug 3023_UP Iodixanol [92339-11-2]; Up 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "RALGAPA1,ANK2,APC,APOC1,SEMA4G,MYOM1,NRP2,BMP7,CACNA1I,CACNA1G,KALRN,CHN2,PICK1,EXOG,EDN3,CNNM1,F5,ALDH1L1,PCDH17,RUNDC3A,GLI2,GPR37,SPACA9,SMAD1,CCSER2,PLXNB1,PPARA,PTPRN2,RGS4,SCN8A,ZNF821,ST8SIA1,DDN,TACR1,PHF24,TIAM1,SSBP2" Drug 2626_DN N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "C1QTNF3,APBB2,ARHGDIG,KIF1A,SYNJ2,CCNT1,PLEKHB1,SLC4A8,SIPA1L1,DAPK3,DNM1,EGFR,IRAK4,ING4,CDKL3,FHL1,ERAP1,GNG4,GPER1,BTN2A1,MAP4K5,HNMT,LIG4,MAP4,SLC11A2,RETREG1,ZCWPW1,ZDHHC14,SH3BP2,SNCA,CAMTA2,CEP68,ANKRD12,PARD3,CABIN1,XRCC4,ZBTB14" Drug 3864_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LTBP4,SEMA7A,APOC1,SEMA4G,PTCH2,CFAP410,CAMK2B,CDO1,SULT4A1,PICK1,AKAP5,CRY2,TMCC2,ETV1,DLC1,AGAP2,FYB1,SIGLEC8,CPLX2,SRCAP,CSDC2,GPER1,IRF8,KCNJ5,KIT,MSR1,FXYD7,PDE1C,TMOD2,SNAP25,ZSWIM8,IZUMO4,ARHGAP26,SPTB,ARC,HEY1,PARP11" Drug 5449_DN Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG3,C1QTNF3,LTBP4,PPFIA3,ARHGDIG,MARK4,SYNJ2,SCAPER,KYAT1,MAGI1,ARHGEF6,NECTIN3,MAML1,RUSC2,EIF4G2,FER,FHL1,SEMA4D,KPNA5,ADAM22,ZNF862,SLC11A2,MINDY2,ASAP3,SLC6A8,LIMCH1,ERC1,TSPYL2,PLCB1,MCF2L,EXOC7,IQCE,CHST8,AP4E1,PARD3,ZFP37,MPPE1" Drug 2398_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ALK,ANK2,MARK4,NCOA1,SCAPER,LDLRAD4,CFAP410,CAPN3,CST3,SLITRK5,MAML1,FRY,TNK2,MAN1B1,OGG1,SMIM7,TMEM231,CEP97,ZNF493,RET,GSTCD,TCP11L1,SH3BP2,ZKSCAN3,DOP1A,ARHGAP26,DBNDD2,DDN,IQCE,TBL1X,TSC2,PLPPR2,VIPR2,TFIP11,MARCH8,IFT88" Drug 6326_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASPHD1,MTUS1,ADGRF5,APAF1,APC,EPB41L5,KIF1A,CFLAR,SYNJ2,MTMR3,SCARB1,B4GALT6,NRXN3,AKAP7,WHRN,ARHGAP24,PARD6A,FAM13A,F5,FGF1,SIGLEC8,SEPT9,GFER,GIT1,NDP,NOVA2,PTPRH,ZCWPW1,RASGRF1,NEK11,KCNIP1,KIF16B,KDM4C,CRTC1,CABIN1,VGF,KCNAB1" Drug 2211_DN Astemizole [68844-77-9]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,AK2,APBA2,KCNAB2,SEMA4G,SLC4A4,ATP6V0A1,ADAM15,TAOK2,LHX2,ARHGEF4,SEC14L5,CDON,EGFR,TMEM164,SEMA4D,FAM49B,CSPG5,GLYR1,GPER1,SPACA9,GRIK5,CACFD1,GSN,MUM1,JAK2,MBOAT7,GSTCD,NEK11,TCP11L1,MAP6D1,EMID1,SLC22A4,SMARCD3,EXOC7,VGF,ACTR3B" Drug 3785_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ALK,SEMA7A,APC,ADGRB2,BCHE,IL33,RUNX1T1,LY86,CSF1,DCAF4,DUSP9,CDKL3,FGFR1,HPCAL4,FAM49B,NEU3,GFER,CACFD1,SHISAL1,TJAP1,KCNB1,MIA2,NPR2,NTRK2,CLDN11,SNRK,SUSD4,GAL3ST4,RGS4,TSNAXIP1,UNC5B,SPTB,TRIM2,TNS1,CDK20,LAT2,GAN" Drug 6455_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SEMA6A,AMPD3,APBB2,KIF1A,WHRN,CREM,CSF1R,GPRASP1,DGKG,CDON,EDNRA,AASS,F5,FER,FGF13,INPP5K,SRCAP,PCLO,RASSF8,HAS2,KCNH2,MMP16,ADAM22,NEFM,PAX6,DUSP26,SLC25A23,PTCH1,RGS12,KCTD17,TCP11L1,ST6GAL1,LIMS2,RBM26,WIPF1,ZNF711,SLC30A3" Drug 2537_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADCY6,ALK,DDO,PDE8B,HAP1,EPS15L1,STOML1,CRMP1,CRY2,SEC14L5,ZNF337,DGKG,GSDME,TMCC2,E2F5,CNNM1,FLT1,GFER,GLI2,GNAO1,MYO6,NPR2,P2RY1,PPP1R1A,SUGCT,EMID1,SEMA6D,ZNF821,ABLIM3,FAIM2,SPTB,SYT1,WSCD1,CRTC1,AP4E1,TRPS1,SLC17A7" Drug 6657_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BRAP,ADRA1D,TRMT9B,AMPD3,CBFA2T2,RAB28,AATK,VCAN,PPP6R2,LYPD1,CHRDL1,HIPK3,PLXNC1,AASS,ZNF44,SEPT9,HSF2,KHK,MAPT,TM6SF1,NF1,NFYA,CNOT4,PPP5C,MAPK7,NEK11,SUPT20H,PREX2,BTBD7,ZNF667,UNC5B,TROVE2,TMEM121,CABIN1,TPM2,OSBP2,WIPF1" Drug 4150_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,BIN1,FAM131A,ALDH7A1,NRP2,PLAA,WHRN,RCHY1,SH2B1,CRMP1,CRY2,SPOCK2,HIPK3,ELN,ERCC2,DLC1,OLFM1,FGFR1,FHL1,SEPT9,LYVE1,TJAP1,MX1,MYT1,CNOT4,MINDY2,PPP2R2B,ZNF821,SH3BP2,LIMS2,FAM214B,SLC6A8,ZHX3,ZC3H13,SYT5,PCDHA5,PLSCR4" Drug 3990_UP Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADAM23,SCAPER,CBS,PLEKHB1,TPP1,AKAP7,CSF1R,CSNK1E,EDNRA,HIPK3,TNK2,COQ7,ETV1,TRMO,GNG4,GPER1,GRIK5,GRM2,TM6SF1,MX1,MTRF1L,LRRN3,ELOVL2,PTPRB,PTPRN2,ACSS3,BEND5,RET,KCNIP1,CNKSR2,PREX2,ZNF334,SYT5,CRTC1,LMF1,ZNF24,DPF3" Drug 4185_UP Probenecid [57-66-9]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "KCNAB2,APC,CDK10,ZSCAN18,BACH1,BCHE,NRP2,GYG2,CACNA2D1,SCARB1,CRY2,DTNA,HIPK3,IRAK4,COQ7,ZNF589,B4GALNT1,TOX3,STON1,MCHR1,HNMT,AFDN,NTRK2,ENPP2,PRKCB,ELOVL2,GAL3ST4,RNASEL,SUPT20H,ZFP30,DZIP1,SNCA,TROVE2,COBL,TBCEL,TNS1,TPM1" Drug 6446_UP Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,ALCAM,BEGAIN,KCNAB2,APOC1,PPP4R4,PDE8B,CFAP410,CLGN,CHRNA4,SULT4A1,HOMER3,CPS1,ARHGEF10,MFAP3L,EGR3,RASGRP2,SIGLEC8,GFER,GNAO1,ICA1,IRF8,JAK2,MAPT,ADAM22,SMOX,SLC25A23,LRP12,PPP5C,MAPK7,RET,SYBU,SLC11A1,PEG10,PCDHA6,RIMBP2,FAM13C" Drug 6635_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LTBP4,AMH,DDO,BACH1,SYNJ1,MYRF,CAMK2B,ARHGEF2,SOCS6,TAOK2,VCAN,PDE4DIP,CNTNAP2,CHRDL1,ING4,ZNF391,FGF1,AHDC1,KCNN1,ADAM22,PALM,PRKAR1B,ELOVL2,C1orf54,PREX2,PEX26,SP2,ZC3H13,SPTAN1,PHLDB1,MCF2L,TBCEL,CDK20,WIPF1,XRCC4,ZNF24,AAAS" Drug 2552_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AMH,AMPD3,OGT,AZGP1,KSR1,KALRN,HIP1R,SLC16A4,CDH2,CHRNA4,RGS6,EDNRA,FGFR3,GAA,SIGLEC8,ALDH1L1,LYVE1,GUCY1B1,KCND1,KCNJ5,ADAM11,NTRK3,POU6F1,ACSM5,SUGCT,PNMA8A,SCN2B,ASAP3,CCDC92,PEG10,CLSTN2,PLCB1,TNS2,THRA,RIMBP2,TRO,FAM155A" Drug 2394_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BRAP,ALK,NCOA1,BCL7A,LDLRAD4,CAPN3,CD86,TMEM184B,IQCK,C2CD2,OSBPL3,VCAN,DTNA,COQ7,VPS26C,FECH,TPK1,LILRA2,LPAR4,IFI16,ITGA7,MAP4,SLC11A2,RETREG1,LRP12,RET,ATXN2,CCDC88A,ZBTB43,DDN,EXOC7,HIF3A,SLC44A1,TK2,KAT6B,ATP6V0E2,ST7" Drug 2622_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NME5,MARK4,LDLRAD4,TPP1,AKAP7,WHRN,ARHGEF10,PDE4DIP,MFAP3L,SPOCK3,CDON,SLC12A6,TNK2,RCAN2,DLC1,SEMA4D,SRCAP,GNAL,GRIK5,GRM2,GRM8,HAS2,LMO2,ADAM22,ZNF862,NPY,SAMD9,SNAP25,KDM4C,ZC3H13,IQSEC2,SMG6,CRTC1,HIF3A,TLR4,TIGD6,AP3B2" Drug 2693_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABHD6,FZD9,MTUS1,PKP4,SEMA4G,PLA2G4C,BMP7,CACNA1G,CFAP410,SCARB1,SYNGR3,HOMER3,CREM,ABCG1,SUSD5,FAM169A,FAM131B,DGKG,DAPK3,HIPK3,FER,FHL1,ERAP1,LYRM9,PCDH9,CNNM2,RAD51D,SUGCT,FAIM2,DOP1A,TROVE2,ST5,ZNF34,TRPS1,ZFP37,ZBTB38,ZNF225" Drug 5483_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AGT,LTBP4,BIN1,FAM131A,CFLAR,LHX2,CRYM,DGKG,C2CD2L,HSD17B14,PTK2B,ZNF589,BAIAP2,AGAP2,PRELID3A,SRCAP,MALT1,HLF,INPP5B,KHK,MEF2C,CNOT4,NTRK2,MTRF1L,PPP2R2B,PRKCB,GDPD2,ZKSCAN3,HECW1,TROVE2,SMG6,CRTC1,RIMBP2,PIK3R5,VIPR2,LAT2,ITM2C" Drug 6297_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NME5,DOC2A,SEMA7A,BAIAP3,CFAP410,CACNA2D1,SCARB1,TAOK2,HOMER3,CSF1,PDE4DIP,BRINP1,EIF4G2,IRAK4,STX2,ST3GAL6,ZNF589,FLT1,GLI2,HSF2,IRF8,KCNB1,CLDN11,MINDY2,PTCH1,BEND5,GSTCD,SCN8A,DZIP1,SLC2A5,HECW1,WNT7A,ZBTB14,NT5M,EVI5,KCNAB1,DPF3" Drug 4808_DN Benzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABHD6,BIN1,CDC14B,STX16,MTMR3,MTMR2,HAP1,MAGI1,LHX2,AKAP7,USP6NL,EDNRA,OPTN,MRNIP,SCML2,FHL1,FAM49B,PRELID3A,GAD1,COPS8,MAP4K5,DHX35,IPO5,MAP4,MITF,LYRM9,NEK1,CEP97,RGS12,KCTD17,ANKRD6,CDK5RAP2,TTBK2,DOCK9,TMEM121,VGF,XRCC4" Drug 2256_DN Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,LTBP4,BIN1,CFLAR,CAMK2G,SPAG9,CCNT1,CACNA2D2,DAPK3,PLXNC1,SRCAP,TXNL4A,SPIN1,POLL,GNG4,GRIK5,IL6ST,ITPKB,MAP4,MIA2,ZNF862,NF1,PCDH9,PIK3R1,MSANTD2,SLC25A36,GSTCD,SBF1,ZNF821,RBM34,CDK19,TBL1X,CRTC1,ZBTB14,SLC30A3,SEMA3B,PHTF2" Drug 5347_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APBB2,MARK4,ALDH7A1,SCAPER,SOCS6,TAOK2,QKI,ARHGEF4,SPOCK2,DTNA,SUGP2,DENND4A,ZNF589,FECH,FGF12,FGFR1,GLYR1,FERMT2,GPER1,LSS,MID1,MITF,NACA,NEK1,PDE4B,POLG,NKAIN1,SEC14L1,ZFP30,SH3BP2,SMARCC2,ZBTB43,TBCEL,ZNF34,LAT2,ZNF74,MPPE1" Drug 6799_UP Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "PDE8B,MARK4,ATP2A2,CACNA1A,ARHGEF1,CLGN,TAOK2,SULT4A1,CDC42BPB,RASSF2,ANKMY1,ZNF589,PDLIM5,HLF,KHK,KIT,MEF2C,MPP2,MSI1,OGG1,EMID1,PEX26,FAM214B,ZSWIM8,CAMTA2,STX1A,CRTC1,PCDHA6,TMEM121,TK2,TPM2,TRIO,FAM155A,KCNK12,ITM2C,EPM2A,KAT6A" Drug 5082_UP Isometheptene mucate; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASPHD1,ADGRB1,BAIAP3,LDLRAD4,CACNA2D2,RAB26,AKAP6,SUSD5,FAM131B,ECM2,FRY,COQ7,CORO2B,EFCAB2,PRELID3A,GATM,RUNDC3A,GNAO1,SPACA9,KCNF1,KCNJ5,MAPT,MATN3,TREM2,PID1,CNKSR2,SNAP25,SNCA,HECW1,DDN,TACR1,MCF2L,KIAA1107,SYNE1,R3HDM1,CHST5,SEMA3B" Drug 4791_DN Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "CDC42BPA,BCAS1,ARNTL,CA12,ARHGAP33,VAX2,AKAP7,SH2B1,DBT,PARD6A,DTNA,MAMLD1,CNNM1,ENO2,FHL1,ERAP1,DIDO1,MAP4,MAPT,LYRM9,NFYA,RETREG1,PLEC,WDR25,GTDC1,SBF1,EPN2,IQSEC2,TROVE2,KIAA0930,TMEM121,TK2,ZKSCAN5,VAV1,VGF,ZBTB14,ST7" Drug 3005_UP Suprofen [40828-46-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ACHE,SEMA6A,CDC42BPA,AZGP1,CACNA1G,HIP1R,CBFA2T2,SYNGR3,DGKI,CHGB,AKAP6,WHRN,RGS6,SNPH,MFAP3L,EXOG,ING4,SRPK3,KHDRBS3,NEU3,GLI2,SCIN,PACRG,MBP,AFDN,MSR1,MYT1,NOVA2,NTRK2,PCDH9,PPP2R2B,RGS4,PEG10,ATP10B,PHF24,HIF3A,SSBP2" Drug 2425_DN Naringin hydrate [11032-30-7]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ABR,GAS7,CASK,ARNTL,SCAPER,MTMR2,C5,SLC25A14,SPAG9,QKI,SOCS5,DBT,DTNA,ING4,ZNF589,PCYOX1,TRMO,LILRA2,KIF2A,IPO5,MAP4,ZFYVE21,PLCB2,SLC25A23,MINDY2,MAPK3,ZSCAN32,SAFB,SEC14L1,NXT2,ANKRD12,ZEB1,KAT6B,ZNF24,LAMP5,PHTF2,NLRP3" Drug 6426_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MTUS1,APLP1,PPFIA3,SLC4A4,SYNJ2,CBFA2T2,CNOT8,RAB26,PHF14,LYPD1,SPOCK3,F8,DLC1,BAIAP2,DISC1,SRCAP,POLL,TJAP1,KIFC3,TAGLN3,NEK1,NF1,NLE1,BCAS3,FAM184A,ZDHHC14,NEK11,RXRA,FBXO11,ZNF415,TROVE2,ST5,TK2,BEX4,WNT7A,XRCC4,DPF3" Drug 1940_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AK2,PPFIA3,BARD1,C2CD2L,LYPD1,EXOG,SEZ6L2,APH1A,TMEM164,AMOTL2,ATP2C1,TRAF3IP2,CACFD1,MAN1B1,MBNL1,SETD4,TRHDE,STRN3,PPM1B,TMEM260,PTX3,RIPOR1,QDPR,ZFHX4,HSPA4L,NMNAT2,ZBTB43,DIP2A,ANKRD12,IQCE,OBSL1,FRYL,CBX5,TSN,ZFAND5,MPPE1,ACTR3B" Drug 2842_DN Tolazamide [1156-19-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "SHROOM2,ARHGDIG,CFAP410,AP4M1,RCHY1,SIPA1L1,DAPK3,DBN1,EDNRA,EGFR,EIF4G2,SCML2,PRELID3A,CSPG5,SRCAP,MALT1,RAB30,HNMT,MPP2,GIT1,LYRM9,NEK1,SLC11A2,MBOAT7,PRPH,ZDHHC14,FUZ,FBXO11,EPN2,ZKSCAN3,RBM34,ZHX3,ARC,CRTC1,SLC44A1,PARD3,HPS4" Drug 7256_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LGR5,SLC4A4,RIPK1,BID,CBFA2T2,CNOT8,RAB28,NRXN3,SULT4A1,NCOR1,ARHGEF10,TBC1D5,DYNC1I1,FAM13A,REEP2,FER,BAIAP2,AMOTL2,TRMO,CSPG5,SHISAL1,KIF2A,NF1,NFYA,SLC11A2,FNDC3A,ZBTB43,SPART,IQCE,ZMAT3,ZNF34,TK2,XRCC4,ZNF142,EPM2A,FZD3,ACTR3B" Drug 592_DN probucol; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BIN1,OGT,APAF1,APOC1,ARNTL,ARSE,NRP2,CFLAR,ARHGAP33,SEC14L5,DRP2,RCAN1,SUGP2,APH1A,ZNF589,HPCAL4,GALC,GLYR1,PTPRT,NXPH3,ATXN2L,C2orf72,IGF1,STMN1,AFF1,PALM,PFKFB2,GSTCD,FUZ,SLA,DOK5,PHLDB1,COBL,TNS2,TRIO,VAV1,AAAS" Drug 5874_DN Praziquantel [55268-74-1]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BRAP,APBB2,CDC14B,MARK4,ALDH7A1,SOCS6,TAOK2,NRG2,VCAN,DCAF8,DBN1,DBT,ZNF804A,ING4,MFSD10,COQ7,BAIAP2,FHL1,PRRC2B,IFI16,FAM69A,MAP4,SCAMP5,MITF,ZNF862,MAPK3,PTCH1,PTN,RIPOR1,WDR37,TSPYL2,TROVE2,POGZ,SYT1,TRIM2,NPDC1,EMSY" Drug 2893_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LTBP4,APOC1,ADAM15,BCL7A,BMP7,ARHGEF1,ARHGEF2,QKI,NECTIN3,SOCS5,PDE4DIP,MFAP3L,EXOG,DTNA,ZNF589,B4GALNT1,MSL3,GSN,TJAP1,KCNH2,NPR2,NLE1,PRPH,ELOVL2,FAM184A,SYBU,EPN2,TTBK2,STX1A,PDLIM2,UBE3A,PLPPR2,LMF1,SEMA3B,ST7,SMIM8,PHTF2" Drug 6332_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "CDC42BPA,GAS7,SEMA4G,PTCH2,KIF1A,CACNA1I,RUNX1T1,LHX2,ABCG2,CABP1,NCOR2,AATK,CSNK1E,PDE4DIP,RIPOR2,ARHGAP24,DTNA,FAM13A,RASGRP2,AFF2,DISC1,MAPT,ADAM22,NDP,GAL3ST4,KCNIP1,FRMPD1,SLA,SLC2A5,HECW1,CEP68,ASTN2,SYNE1,NSD1,CRTC1,FLRT2,DPF3" Drug 6727_DN Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASIC1,EP400,TAOK2,FAM169A,DZIP3,PPP6R2,MFAP3L,AASS,MRNIP,VPS13B,SPEG,ETV1,ANKMY1,RRAGB,ZNF589,FYB1,DENND2A,POLL,MGAT3,NF1,OGG1,PRKAR1B,GRAMD1C,PRPH,ATXN7,LIMCH1,PHLDB1,KIAA1107,RPGRIP1L,NSD1,TK2,PLPPR2,VGF,WIPF1,XRCC4,ZNF45,ADAMTSL3" Drug 2281_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "LTBP4,TRMT9B,SEMA7A,ARHGDIG,N4BP2L1,HAP1,TAOK2,RIMS2,SPOCK2,SPOCK3,ING4,ERCC2,DLC1,SCARA3,NEU3,PRUNE2,GPER1,ADAMTS13,GUCY1B1,KCNB1,MAP4,MEF2C,NEFM,NNAT,PALM,ENPP2,PDZRN4,SEMA6D,ASAP3,CPEB3,SNAP25,ZC4H2,JMJD6,DMXL2,CHST8,OSBP2,FLRT2" Drug 5253_DN Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ALCAM,ALK,APC,DNAH17,SYNJ1,FOXN3,HOMER3,ARMC8,CNTNAP2,PHF14,RASSF2,PIPOX,ANKMY1,KAT8,ZNF589,FGFR3,IQCG,RAB30,RASSF8,MAPT,MMP16,MPP2,WDR25,ZFHX4,SLC9A5,CXXC4,SNCA,ZC3H13,PLCB1,EXOC7,TBCEL,WSCD1,ZBTB14,EVI5,FIP1L1,ADAMTSL3" Drug 6262_DN Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ALCAM,ARRB2,BMP7,MTMR2,NFS1,NCOR1,ABCG1,PPP6R2,KIAA0586,GIT2,KIAA0753,PARD6A,SCML2,PDLIM5,GRB10,CLASRP,MAP4,MAPT,NCAM2,NEK1,OPA1,STRN3,PPP3CC,RAD51D,RCOR3,TMCC1,TACC1,DNMBP,TBL1X,OBSL1,BHLHB9,NPL,METTL3,HIRA,UBTF,VAV1,MAP3K12" Drug 7151_UP Sulfapyridine [144-83-2]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BIN1,LGR5,CDK10,EIF4G3,ALDH7A1,ADAM15,SCARB1,SOCS6,ARMC8,AKAP5,HAPLN1,MAMLD1,EGFR,DENND4A,ANKMY1,BAIAP2,SCARA3,OGA,FYN,GAD1,TXNL4A,SYNPO,JAK2,MN1,PDE4A,BCAS3,ZCWPW1,RGS4,ZFP30,ASAP3,PEX26,PPP4R3A,SLC6A8,IZUMO4,TRIM2,WNT7A,DPF3" Drug 2074_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MTUS1,NME5,SEMA4G,CDK13,MARK4,BCL7A,MYRF,NRG2,CDC42BPB,CREM,CSF1,PDE4DIP,SLITRK5,ARMCX2,KLHL3,EDNRA,FCF1,EGFR,MRNIP,VPS26C,RRAGB,GLYR1,KCNMB4,SHISAL1,IL6R,ZNF426,MAPK7,SNRK,FBXW7,SUPT20H,FNDC3A,KDM4D,SLC22A4,TIAM1,SSBP2,XRCC4,MARCH8" Drug 4116_DN Cefotetan [69712-56-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "AK2,CDK10,ARHGDIG,SLC2A11,KRIT1,SOCS6,STOML1,PRKAG2,CGREF1,RUNDC3A,GLYR1,PCLO,CNTRL,ELOVL5,MATK,MBD1,MITF,MPP2,ADAM22,MTRF1L,ELOVL2,RIPOR1,CARF,FBXW7,MAPK12,ZNF821,PPP4R3A,TROVE2,ITPRID2,PLCB1,PDLIM2,CHST8,PARD3,CABIN1,RUNDC3B,EVI5,SEMA3B" Drug 4315_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ADD2,FAM135A,APAF1,ARRB1,CDK13,PTCH2,ADAM15,FUBP1,BAIAP3,NRXN3,TPP1,SH2B1,ABCG1,CYBB,DAPK1,DTNA,AASS,TENM1,PRELID3A,GDF9,LILRB4,PTPRT,ICA1,KCND2,NCAM2,PDE4A,PTPRN2,CCDC40,RASGRF1,RFX2,RYR3,OGDHL,DOP1A,IQSEC2,SSTR1,UCHL1,LAT2" Drug 2272_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "RALGAPA1,C1QTNF3,APBB2,GAS7,APLP1,APOC1,PPP4R4,PLA2G4C,RASL11B,CFLAR,FOXN3,PLEKHB1,QKI,CRY2,GREB1,PLXNC1,COQ7,PRELID3A,SRCAP,GLYR1,DHX35,JAK2,IPO5,ZNF862,MYT1,RETREG1,PRODH,RGS3,TCP11L1,SH3BP2,LIMCH1,SPART,TROVE2,PHLDB1,AP4E1,KCNK12,HPS4" Drug 7462_UP DO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "BIN1,APOC1,KSR1,SCAPER,MTMR3,FOXN3,SOCS6,TBC1D5,SLC12A6,MBNL2,MRNIP,ENO2,SEMA4D,RAB30,GPER1,DHX35,MMP16,TAGLN3,LYRM9,NTRK3,TREM2,LRP12,WDR25,CCDC25,SH3BP2,ZHX3,UNC5B,ARHGAP26,TSPYL2,VPS13A,AP4E1,PIK3R5,TRIO,ZBTB14,MPPE1,HRASLS,PHTF2" Drug 5491_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "NDRG2,ADGRF5,AMPD3,BIN1,CDC14B,SCAPER,USP2,ARHGEF1,NRG2,AATK,IPCEF1,MBNL2,ELN,SPEG,SRCAP,DHX35,TJAP1,KCNH2,GIT1,OPRL1,MTRF1L,LRP12,RGS4,KLHDC8A,RPS6KA2,ZNF821,MRAS,SH3BP2,SLC6A8,ZNF334,TMCC1,TROVE2,PLCB1,RIMBP2,TRPM2,LMF1,KCNK12" Drug 3755_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APAF1,CDK10,PPP4R4,RASL11B,KIF1A,BAIAP3,SYNGR3,CD38,DCLK1,RAB26,RIPOR2,ECM2,NCALD,REEP2,PTK2B,GATM,ALDH1L1,RUNDC3A,GNG4,KCNB1,KCNN1,MATN3,MSI1,GPR85,PGAM2,MAPK10,PTH1R,PTPRG,PTPRH,PTPRN2,KCTD17,HUNK,MYH15,SPTB,LMO3,PIK3R5,KCNAB1" Drug 7168_DN Diazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "ASPHD1,AP2A2,AK2,APBB2,CDK10,NUMB,ENTPD6,FOXN3,HOMER3,CREM,CSNK1E,OPTN,STX2,PDLIM5,OGA,SYT17,SRCAP,PADI2,DHX35,KCNF1,LSS,MAP4,MATK,CNNM2,MAPK12,FNDC3A,PEX26,ZHX3,ZBTB43,EXOC7,BEX4,RPRM,PLPPR2,VAV1,REEP1,MAP3K12,GAN" Drug 2060_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "MTUS1,AMPD2,APBB2,MARK4,ADAM23,MTMR2,ARHGEF1,SYNGR3,CLCN3,IQCK,ABI3BP,LYPD1,PLPPR4,DPH1,FAM13A,MBNL2,ING4,VPS26C,GPER1,TAGLN3,MX1,PTPN13,PTPRN2,FAT4,GTDC1,NEK11,CSRNP3,KDM4D,FNBP1,KDM4C,CAMTA2,KIAA0930,ZNF34,EMSY,FZD3,MARCH8,ACTR3B" Drug 524_UP nordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 1.57E-03 1.00E+00 1.17E-02 1.32E-01 37 198 "APAF1,ARRB2,MARCH3,SLC4A4,ATP6V0A1,ARHGEF2,ARHGAP33,CLCN3,RIMS2,GIT2,TNK2,CD320,PTK2B,SEMA4D,NSG1,SYT17,RUNDC3A,SOX21,NXPH3,L1CAM,ADAM22,ENPP2,CCSER2,MBOAT7,POLR2F,PRKAR1B,ACSM5,RBBP6,SEMA6D,FUZ,CDK5RAP2,SNCA,ZSWIM8,ZC3H13,FAM189A1,R3HDM1,USP1" Drug 2723_UP Cycloheximide [66-81-9]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.58E-03 1.00E+00 1.18E-02 1.32E-01 33 171 "BRAP,SPARCL1,DNAH17,SYNJ1,CD86,CHRNA4,COL9A3,CREM,SIPA1L1,EGR3,TLR7,BAIAP2,ZNF44,TRAF3IP2,PCLO,SPACA9,MEF2C,MGAT3,NOVA2,PDE4B,PPP1R1A,PTX3,SUGCT,SCN2B,SH3BGR,ATF7IP,ZNF415,DOP1A,SAMSN1,SYT1,UBE2H,LMF1,XRCC4" Drug CID000177965 T-440 Stitch 1.59E-03 1.00E+00 1.18E-02 1.33E-01 9 26 "PDE8B,ALDH7A1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PTPRN2" Drug CID000000702 ethanol Stitch 1.59E-03 1.00E+00 1.18E-02 1.33E-01 123 837 "ASIC1,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,APOC1,APOC2,SPTBN4,ALDH7A1,ATP6V0A1,LDHD,CACNA1I,CA4,CA8,CA12,CACNA1B,CALM1,CCK,KRIT1,CD86,LRBA,DLGAP2,NOG,ASIC3,CHRNA4,NRXN3,CNR1,CNTFR,ENTPD4,CRHBP,CS,CSF2RA,PLCXD3,GPSM1,DBI,GRIN3A,AASDH,EDN1,EDN3,EGFR,EPB41,COQ7,STX2,ERBB2,ERBB4,PPP1R1B,POLK,PCYOX1,GABRA3,GABRB3,GABRG1,GABRG2,ACSS1,GCK,GFRA2,GGT7,GGT5,GPT2,GPD1,GPD2,GRIA2,PLCD4,GRIN2C,GRIN2D,GSTM5,GSTT2,HBA1,TNFAIP8L3,MYLK2,IGF1,IL6ST,IL12A,ITGAM,JAK2,L1CAM,LIFR,MBP,NPY,NTRK2,NTRK3,OPRL1,PDCD2,PIK3C2A,PIK3R1,PKM,PLCB2,PLCD1,POLG,PPARA,PPP2R2C,PPP2R5E,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PPP2R3C,ACSS3,REV3L,MAPK12,SCN7A,FNDC3A,SPP1,PEG10,SPTAN1,SPTB,CLSTN2,SST,APOM,ADHFE1,PLCB1,SYT1,TACR1,SMG6,TK2,PIK3R5,CA14,ZNF142" Drug CID000068933 BT325 Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 11 36 "SYNJ2,ABCG1,DBI,DMD,DTNB,STMN2,BLOC1S2,ATXN7,SLC14A1,P2RY12,HPS4" Drug CID000159325 torcetrapib Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 11 36 "APOC1,SCARB1,ABCG1,FDFT1,HMGCR,GPR85,PLTP,PPARA,SLC12A4,P2RY12,NETO1" Drug CID000007992 iBVE Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 11 36 "APBA2,APC,CLTC,ARHGAP32,EXOG,ACOT8,MALT1,POLG,PTPRN2,ST5,RTN4" Drug ctd:D009966 Orphenadrine CTD 1.60E-03 1.00E+00 1.18E-02 1.33E-01 64 390 "METAP1D,PLEKHH1,ADORA1,ADORA2A,ADRB2,ABCD2,ZBTB10,ATP2B2,SYNJ2,MYRF,IL33,MTMR7,B4GALT6,ARHGAP22,TMEM184B,MAP4K4,TOGARAM2,ARHGEF10,SPOCK2,DPP6,CALCRL,MTSS1L,ADGRV1,F8,ARMCX1,AMOTL2,MEX3B,IP6K2,FLT1,CGREF1,TOX3,LILRB4,GRIK5,KCNH2,NCOA7,MID1,NEFH,NINJ2,NPY,DNHD1,ZDHHC8,SNX10,PMP22,IRX1,PPP1R1A,PTPRN,ERI2,MAPK12,MRAS,SGK1,FAM102A,ABLIM3,SLC6A8,SLC12A4,ZNF334,BTBD7,UNC5B,DIP2A,STXBP1,TBCEL,CSMD1,TNS1,TPM1,TRPM2" Drug CID003081782 KS-505a Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ALDH7A1,CALM1,KRIT1,GPR162,PDE1C" Drug ctd:C459562 "L-826,141" CTD 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "PDE8B,PDE3A,PDE4A,PDE4B,PDE4D" Drug CID009898619 Depreotide Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "MCHR1,SST,SSTR1,SSTR2,SMUG1" Drug CID000194954 Hexapeptide 4 Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "MCHR1,SST,SSTR1,SSTR2,TACR1" Drug CID000016247 aminocarb Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ACHE,AMH,BCHE,DNMBP,TUBA1A" Drug CID000445281 X Bb Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "MCHR1,FOXRED1,SST,SSTR1,SSTR2" Drug CID005486761 K00271 Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "BLM,MYT1,PCMTD2,NSD1,TEK" Drug CID000054765 bambuterol Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ACHE,ADRB2,BCHE,PRIMA1,SALL1" Drug ctd:C000603500 4'-methoxy-1-naphthylfenoterol CTD 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ABCG2,ABCC5,EGFR,ABCB1,PKM" Drug CID000181428 FK960 Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ACHE,BCHE,MAPK9,MAPK10,SST" Drug CID000017517 isoprocarb Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "ACHE,BCHE,CLTC,FXYD1,PBRM1" Drug CID000016180 amino-L Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "BCHE,HDAC9,PDLIM5,GSN,SAFB" Drug ctd:C035964 trequinsin CTD 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "PDE8B,PDE3A,PDE4A,PDE4B,PDE4D" Drug ctd:D002186 Cannabinoids CTD 1.60E-03 1.00E+00 1.18E-02 1.33E-01 5 9 "CALM1,CAMK2B,SCARB1,FDFT1,SEMA3B" Drug CID000003278 ethacrynic acid Stitch 1.60E-03 1.00E+00 1.18E-02 1.33E-01 28 138 "ADCY5,ADCY6,ADCY8,ATP1A1,SLC4A4,KIF1A,SGCE,CA4,CA12,CBR1,ABCC5,EDNRA,GSTM5,GSTT2,KCNK3,KIF2A,KIF5A,KIFC3,ABCB1,MAPK3,KIF7,GSTCD,KIF27,KIF21A,KIF16B,SLC12A4,KIF13A,TBL1X" Drug 1321_UP Apigenin [520-36-5]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.63E-03 1.00E+00 1.20E-02 1.36E-01 34 178 "AK2,AMH,C5,LDLRAD4,CCNT1,CREM,DNAJB6,ANKRD46,FEM1B,FCF1,EGR3,CDKL3,KAT8,CELF1,ALDH1L1,DIDO1,FICD,LSS,MT1M,CNOT4,PDE4D,SMIM7,PTPRE,CCDC25,FNDC3A,KBTBD4,MYH15,IZUMO4,ZBTB43,PBLD,CBX5,MKRN3,KCNAB1,KAT6A" Drug CID000005202 serotonin Stitch 1.63E-03 1.00E+00 1.21E-02 1.36E-01 86 554 "ACHE,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,AMT,APAF1,APOC2,ATP1A1,ATP1A3,ATP1B3,MPDZ,CACNA1I,CACNA2D1,CACNB4,CALB1,CALB2,CAPN3,CCK,CHGB,CHRNA4,CLCN3,CNR1,PLCXD3,SLC29A4,EDN1,ENO2,STX2,SIRPB1,RPS6KC1,ZMYND10,PRMT5,PPP1R1B,GABRB3,GAD1,INPP5K,CBX1,LOXL3,PLCD4,GRM2,CIT,HLF,HP,IGF1,GPR62,KCNH2,KCNJ5,NDP,NPY,NUCB2,OPRL1,P2RY1,PDPK1,PLCB2,PLCD1,POLR2F,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,QDPR,GLDN,RPS6KA2,S100B,MAPK12,SLC6A11,SNAP25,SST,ADHFE1,STX1A,JMJD6,SUPT5H,PLCB1,SYP,SYT1,TACR1,GPR161,ACTR6,P2RY12,SLC17A7,PLD4" Drug CID000073672 isoxaben Stitch 1.63E-03 1.00E+00 1.21E-02 1.36E-01 10 31 "CBS,CNOT8,EDN1,EDN3,EDNRB,RASL12,SEPT4,IRX1,RET,ARX" Drug CID001008511 "1,4-bis-(phenoxyacetyl)piperazine" Stitch 1.64E-03 1.00E+00 1.21E-02 1.37E-01 41 226 "OGT,ATP1A1,STX16,AP1M1,RUNX1T1,AP4M1,CLTC,ABCG1,CSNK1E,CSNK1G3,ZFYVE16,SNAP91,ACOT8,PDCD6IP,TOM1,VTI1B,AGAP2,FOLH1,NBEA,PDLIM5,COPS8,GRB10,GRIN2C,GRIN2D,GRM2,GRM8,IL12A,LAMP2,LSAMP,NF1,NNAT,RET,S100B,SYP,SYT1,P2RY12,SLC30A3,SLC30A4,HPS4,SLC17A7,AP3B2" Drug 7055_UP "Forskolin, from Coleus forskohlii; Up 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "ABHD6,ADORA1,AK2,BCAS1,CFLAR,ST3GAL5,GYG2,CAMK2G,ARHGEF1,ARHGEF2,MAGI1,TPP1,WHRN,PDE4DIP,ZNF589,IQCG,OGA,TRAF3IP2,AHDC1,MALT1,TDRKH,MAP4,PALM,PLXNB1,ZDHHC14,RPS6KA2,PEX26,ZBTB43,MCF2L,CRTC1,WIPF1,EVI5,GDPD5,HPS4,SEMA3B" Drug 5908_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "ADRB2,ARNTL,ALDH7A1,ATP6V0A1,ST3GAL5,HIP1R,USP2,NRXN3,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,MRNIP,RGS17,TAOK3,BAIAP2,PDLIM5,FYN,CYP46A1,PCDH17,ACOT7,FAM69A,MAPT,ENPP2,SERPINI1,RETREG1,RGS4,FBXW7,SH3GL3,ASAP3,ELOVL4,RGL1,SYT1,SSBP2" Drug 3103_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "ALK,BIN1,CDC42BPA,PDE8B,DNAH17,CD86,CD38,RAB33A,ARMC8,ABI3BP,CREM,ABCG1,SIPA1L1,PDE4DIP,PPP1R16B,PHF14,DOCK4,SPOCK2,BAIAP2,GNAL,RNFT2,HNMT,MAP4,MEF2C,PDE4B,PFKFB4,PID1,DOK5,ZSWIM8,IZUMO4,ZC3H13,TK2,RIMBP2,CLIP2,SLC30A3" Drug 6973_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "BIN1,DNAH17,KYAT1,CRY2,ARHGEF10,EIF4G2,ANKFY1,FYN,B4GALNT1,LYVE1,COPS8,DIDO1,SPACA9,GRM8,MAP4K5,IGF1,MAP4,MAPT,MBD1,MYH3,NPR2,KLK6,HSPA4L,SGK1,SH3BGR,PPM1E,FRMPD1,SYBU,PEX26,UNC5B,SYT1,ZEB1,PCDHGA10,FAM155A,FXR1" Drug 7402_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "ADCY6,CDC42BPA,KCNAB2,GAS7,NRP2,SYNJ1,CARS,ARHGEF2,PLEKHB1,TAOK2,EXOG,DPH1,COQ7,CDKL3,EZH1,DLC1,ST3GAL6,FYB1,CSDC2,ZNF276,HMGCR,TJAP1,MIA2,MMP16,CNOT4,PLCD1,TMEM231,C1orf54,FUZ,ARHGEF40,ARFGAP1,DDN,ZKSCAN5,XRCC4,KCNAB1" Drug 6971_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "AMPH,APOC1,ARRB1,DNAH17,ATP2A2,KALRN,CRLF1,ENTPD4,PDE4DIP,FAM169A,TBC1D5,MED12,TSPAN5,RASGRP2,F5,FYN,MAP4,MAPT,CNOT4,PFKFB3,LRP12,KLK6,TCP11L1,SUPT20H,SLC2A5,SLC22A4,LIMCH1,ZHX3,KDM4C,PLCB1,NPL,ZNF24,GDPD5,SEMA3B,EPM2A" Drug 4445_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.23E-02 1.39E-01 35 185 "FAM135A,TRMT9B,GAS7,N4BP2L1,KIF1A,CFLAR,GYG2,CBS,CDO1,CACNA2D2,CSF1,NR1D2,EDN1,EGFR,ETV1,CSPG5,OGA,MSL3,GNG4,PRUNE2,STON1,KCNB1,KCNH2,SMAD1,AFDN,PDE4B,PGAM2,ACSS3,PREX2,ARHGEF40,HECW1,ARHGAP26,SZT2,AMACR,PARP11" Drug CID002724274 tungsten carbide Stitch 1.67E-03 1.00E+00 1.23E-02 1.39E-01 7 17 "SLC4A4,ARHGAP32,DMTF1,CLASRP,MBNL1,NOVA2,PDLIM2" Drug CID005311351 Pd164333 Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000073811 NSC 90 Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug DB01412 Theobromine Drug Bank 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ADORA1,ADORA2A,PDE4B" Drug CID003035933 Dctfpg Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "KYAT1,GGT7,GGT5" Drug CID005274625 myriceric acid C Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000129003 S-312-d Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "APLP1,CACNA2D1,CABIN1" Drug CID000065768 tryptamide Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "MAT2A,SIRT2,SIRT1" Drug CID000128344 julifloricine Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ACHE,BCHE,CACNA2D1" Drug CID014758064 "pyrido[3,4-d]pyrimidine" Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EGFR,ERBB2,ERBB4" Drug CID000004478 AC1L1I9D Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ACHE,ABHD6,BCHE" Drug CID000007735 CHDM Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "DST,TSC1,TSC2" Drug CID000131948 WS009A Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000024585 isopulegol Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "BCHE,STX2,KAT8" Drug CID000005965 BC48 Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ACHE,BCHE,DTNB" Drug CID000011875 2-nitrobenzoyl chloride Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000159861 gracillin Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ABCG2,KITLG,ABCB1" Drug CID000136915 N-phenyliminodiacetic acid Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "CSF2RA,F8,SALL1" Drug DB08299 "4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid" Drug Bank 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "PDE4A,PDE4B,PDE4D" Drug CID000010043 AC1Q2A5Z Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "CHL1,L1CAM,NCAM2" Drug CID000036332 2-ethylacetanilide Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000026761 E106E Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000024375 ZnBr2 Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ARX,SYNE1,ARHGAP9" Drug CID000637429 Calebin-A Stitch 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "ABCB1,MAPK9,MAPK10" Drug ctd:C415840 ZD 2574 CTD 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "EDN1,EDNRA,EDNRB" Drug ctd:C013571 inositol pentaphosphate CTD 1.68E-03 1.00E+00 1.23E-02 1.39E-01 3 3 "IP6K1,IP6K2,IP6K3" Drug 5118_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "AMPD3,CALB2,CAPN3,LHX2,CSF1,CTH,HDAC9,RUSC2,DTNA,TOM1,EPB41,OLFM1,SIGLEC8,GLI2,LPAR4,SPACA9,ELOVL5,ADAM11,ADAM22,PTPRN2,PTX3,ZSCAN2,C1orf54,RGS4,RASA3,SLA,SLC4A3,KANSL3,SNAP25,SYT1,TK2,VIPR2,LAT2,TFIP11,NLRP3,JPH3" Drug 6544_UP 5155877; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "MTUS1,C1QTNF1,KCNAB2,SEMA4G,CASK,ARRB2,ADGRB2,CCNT1,LARGE1,QKI,PICK1,OSBPL3,CDON,CNNM1,IRAK4,TNK2,PIPOX,PRELID3A,TRAF3IP2,ERAP1,GPER1,MUM1,SHISAL1,MAPT,PIK3R1,CCSER2,C1orf54,RPS6KA2,LIMCH1,ERC1,ZBTB43,JMJD6,SYT1,SYT5,TBCEL,EVI5" Drug 4340_UP Ethisterone [434-03-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ASIC1,PKP4,CDC14B,PPP4R4,BAIAP3,GIT2,ZBTB24,SGSM2,EDN1,SEMA3D,OLFM1,FGFR1,ZNF44,RUNDC3A,PADI2,IL6ST,KCNJ5,KIF5A,MAP4,ADAM22,NELL2,NPTX1,STRN3,RGS4,KIRREL1,CPEB3,FBXO11,CNKSR2,ANKRD6,SNCA,IQSEC2,TBL1X,DMXL2,HIRA,KCNAB1,KAT6A" Drug 5442_DN Trifluoperazine dihydrochloride [440-17-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "APBB2,ARRB1,PDE8B,MARK4,GYG2,RAB28,HOMER3,GIT2,EIF4G2,VPS13B,KAT8,ZNF589,SEMA4D,MALT1,GLYR1,HNMT,JAK2,MIA2,MPP2,CNOT4,SLC11A2,PRODH,CEP97,GTDC1,MAPKBP1,RBM34,CEP68,SLC44A1,ZKSCAN5,VGF,LMF1,KCNK12,XRCC4,ZNF45,FTSJ1,RNF170" Drug 1525_UP Chlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ADRA1B,PRX,N4BP2L1,CFLAR,MTMR3,BAIAP3,CAMK2B,ARHGEF1,LHX2,CSF1,ELMO1,MFAP3L,ZNF589,FGF13,AMOTL2,FHL1,POLL,ELOVL5,MIA2,MITF,ZNF862,NOVA2,NPR2,NTRK2,CDK18,PDE4A,PRODH,ZFHX4,RPS20,SYBU,RBM34,ZSWIM8,ARHGAP26,CDK20,VLDLR,MARCH8" Drug 4104_DN Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "AP2A2,MTUS1,AK2,CDC42BPA,PKP4,APOC1,CFLAR,SPAG9,CCNT1,TPP1,GREB1,GIT2,EIF4G1,FGFR1,CRCP,GLYR1,RASSF8,DHX35,IL6ST,INPP5B,MAP4,NEK1,ZSCAN32,RNASEL,TCP11L1,PPP4R3A,COA1,PRRC2C,TBL1X,TMPO,KAT6B,CABIN1,UBTF,VGF,EVI5,KAT6A" Drug 977_DN wortmannin; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ASPHD1,ABHD6,PKP4,ATP2A2,PLEKHB1,LHX2,ARMC8,ENTPD4,LYPD1,MAMLD1,EGR3,POLR1B,FGFR3,NOP56,GHR,MUM1,KHK,CNOT4,PCDH9,SLC25A23,PRKAR1B,GTDC1,ZC3H14,SUPT20H,SGK1,CHD9,FBXO11,DHX30,KANK1,JMJD6,DICER1,ZMAT3,NACC2,METTL3,MAP3K12,EVI5" Drug 6659_DN Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "KCNAB2,APOC1,CDK13,CFLAR,FOXN3,SOCS6,ABCG1,PDE4DIP,DZIP3,TOM1,EDIL3,HSD17B14,ETV1,ZNF589,FER,DENND2A,ERAP1,TMEM8B,INPP5K,USP19,IL6ST,LSS,MEF2C,PIK3R1,CNNM2,WDR25,PID1,SH3TC2,RPS6KA2,CCDC88A,SPART,TROVE2,TRIO,XRCC4,EPM2A,PHTF2" Drug 1929_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "PKP4,STX16,WASF1,DZIP3,DDX46,KCTD3,FHL1,SEC23B,PDLIM5,ATP2C1,OGA,HTATSF1,HAS2,RBPJ,KTN1,PAXBP1,MEF2C,NUCB2,STRN3,PPM1B,VPS13C,C1orf109,RBBP6,WDR47,GLT8D1,PEG10,CLASP2,LARP4,DIP2A,TACC1,TCF4,SIRT1,R3HDM1,UBE3A,ZNF189,EVI5" Drug 2785_DN Rescinnamin [24815-24-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "APBB2,APOC1,ARHGDIG,BMP7,SYNJ1,CAMK2G,SOCS6,CLCN3,HOMER3,NCOR1,SOCS5,PDE4DIP,KAT8,GLYR1,RAB30,GPD2,GPR37,MUM1,HSF2,JAK2,MAP4,MBNL1,KITLG,LRP12,PRKAR1B,CEP97,RAD51D,RET,SGK1,PPP4R3A,DMXL2,TNS2,TMPO,PARD3,UBTF,PHTF2" Drug 1580_UP Furosemide [54-31-9]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "NDRG2,BRAP,C1QTNF3,MAP4K3,APBA2,BACH1,CCNT1,DCAF8,FAM13A,GOLGA7,ENO2,EPB41L2,IGSF6,ACSL4,POMT1,ATP2C1,OGA,GLUL,CLASRP,IFI16,KCNN1,LAMP2,TM6SF1,NFE2L2,PIK3C2A,LRP12,SAMD9,PTK2,SLC25A36,AMBRA1,SLC2A5,KBTBD4,KDM3A,TK2,PARD3,TRIM9" Drug 3188_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ABHD6,MTUS1,APBB2,ATP6V0A1,TAOK2,ARHGEF6,PDE4DIP,CTH,DAPK3,DTNA,FCF1,MBNL2,IRAK4,KAT8,FYN,ZNF44,MSL3,HTATSF1,MAP4K5,MAP4,NF1,SLC11A2,ZCWPW1,RGS3,EMID1,FNDC3A,PPP4R3A,ZHX3,THSD1,NXT2,TRIM2,TK2,TMPO,LMF1,ZBTB14,EMSY" Drug 7485_UP Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "AP2A2,SYT13,SLC4A4,SLC2A11,MTMR3,USP2,CREM,JAKMIP2,SPOCK3,SGSM2,TMCC2,RCAN1,SUGP2,ERCC2,FECH,DISC1,ATXN2L,KCNH2,IPO5,MAPT,PPP2R2B,CNNM2,VPS13C,PTN,RPS6KA2,SEC14L1,SH3BP2,SNCA,ZHX3,TROVE2,SYN2,TRIM2,PCDHA6,TFIP11,UPF3A,SEMA3B" Drug 3753_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ADD2,ALK,CDK10,SPAG9,AP4M1,PICK1,CRMP1,DAPK3,EDN1,ETV1,DCTN2,CINP,ARFIP1,GLYR1,JAK2,MX1,MYO6,NEK1,NF1,NFYA,NPR2,LRP12,PRPH,RGS4,FNDC3A,ELMO2,SMARCA4,PEG10,ATP10B,EXOC7,SMG6,SYNE1,CHST8,GPR161,TMPO,UGT8" Drug 6438_DN 5707885; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "ASIC1,C1QTNF1,APBB2,ATP6V0A1,BCL7A,CFLAR,COL9A3,CSNK1E,ELN,FYB1,TRAF3IP2,ALDH1L1,SRCAP,GPER1,SYNPO,SHISAL1,ITPKA,MAPT,NDP,NFIX,PDE1C,PDE4A,ENPP2,SH3TC2,MCMBP,KBTBD4,HECW1,ST5,JMJD6,COBL,TCF4,HIRA,TRIM9,NDRG4,REEP1,NAV3" Drug 7070_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "MTUS1,BIN1,CDK13,CFLAR,RAB29,CFAP410,CA12,LHX2,BAG4,PDE4DIP,DZIP3,GIT2,KLHL3,ACOT8,EFCAB2,ERAP1,GPER1,GRB10,DIDO1,IFI16,SCAMP5,TAGLN3,SLC11A2,SETD4,PRKAR1B,TCP11L1,FBXO11,SNCA,CAMTA2,JMJD6,DNMBP,SMG6,TCF4,SZT2,CABIN1,ZBTB14" Drug 7176_DN Trifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "OGT,SHROOM2,EIF4G3,ARHGEF7,LARGE1,FOXN3,TMEM184B,IQCK,CREM,SOCS5,CTH,PPP6R2,B3GAT3,E2F5,TNK2,MFSD10,ERBB2,RACK1,FGFR1,EFCAB2,GPD2,MAP4,MEIS1,CCSER2,TMEM104,CEP97,GTDC1,FAM192A,CDK5RAP2,PRRC2C,TRIM2,TRIO,RPRM,VAV1,LMF1,MAP3K12" Drug 23_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "NDRG3,BIN1,GYG2,RAB29,ENTPD6,UBE2L6,CHN1,GAPVD1,ENO2,ARMCX1,BAIAP2,SEC23B,FYN,RAB40B,AGBL5,KCNN1,L1CAM,MITF,MYO6,MYT1,SNX10,PLCD1,SEC14L1,SH3GL3,PPM1E,AMBRA1,SMARCD3,MYCBP2,ZC3H13,STXBP1,COBL,TBL1X,TMEM121,TRIO,REEP1,MAP3K12" Drug 2766_DN Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "CDC42BPA,ARRB1,SLC4A4,STX16,CFLAR,SPAG9,CREM,PDE4DIP,TM9SF4,DAPK3,DTNA,FCF1,KAT8,ZNF589,GLYR1,GRB10,TJAP1,INPP5B,KITLG,NF1,NFYA,SLC11A2,PIK3R1,PLEC,PPP5C,FNDC3A,PEX26,ELMO2,NXT2,PLCB1,DICER1,KAT6B,CLDND1,EVI5,PHTF2,FXR1" Drug 3318_DN Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "RALGAPA1,AP2A2,MARK4,CFLAR,SYNJ1,ARHGEF2,MAGI1,SOCS6,SLC4A8,GREB1,DCAF8,TBC1D5,MFAP3L,RUSC2,FAM49B,DISC1,RUNDC3A,TDRKH,SPACA9,CACFD1,TJAP1,KCNH2,KCNN2,MAN2A2,NF1,LRP12,FBXW7,PREX2,UNC5B,SPART,PCDHA6,PLPPR2,VGF,XRCC4,ZFP37,VPS35L" Drug 2123_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "RALGAPA1,ATP2A2,KRIT1,LARGE1,SOCS6,CPS1,ANKMY1,FGF1,TRMO,DLL3,B4GALNT1,SYT17,PCLO,CLASRP,BACH2,HSF2,INPP5B,KCNN1,SMAD1,PDE4D,MINDY2,PRPH,FAT4,GAL3ST4,AMBRA1,DOP1A,ZHX3,IQSEC2,IQCE,FBXW11,SYNE1,HIRA,UGT8,EMSY,SEMA3B,PHTF2" Drug 6028_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.24E-02 1.40E-01 36 192 "NME5,AMPD3,AMPH,BIN1,N4BP2L1,ADAM23,CBARP,MYEF2,ELMO1,GSDME,MBNL2,RASGRP2,ST3GAL6,NEU3,GCNT2,GFER,PCDH17,GSN,ATXN2L,HLF,TJAP1,ADAM22,NINJ2,CDK18,MINDY2,MAPK7,RELN,FAT4,ZMAT4,KCNIP1,SLC11A1,SNAP25,UNC5B,SPTB,DOCK9,SLC30A3" Drug CID000005772 Lypressin Stitch 1.72E-03 1.00E+00 1.24E-02 1.40E-01 13 47 "ACHE,ADCY5,ADCY6,ADCY8,AGT,PLCXD3,PLCD4,OXTR,PLCB2,PLCD1,DDN,SST,PLCB1" Drug 7029_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "OSBPL1A,PDE8B,ALDH7A1,SCAPER,CA12,PLEKHB1,HDAC4,JAKMIP2,PHF20L1,DLC1,BAIAP2,SEMA4D,AHDC1,GLYR1,CNTRL,SPACA9,RASSF8,ATXN2L,KCNF1,LSS,MAP4,MBD1,MEF2C,MID1,MYCN,NF1,SETD4,PDE1C,FBXO11,FNBP1,ASTN2,MCF2L,KIAA0930,SLC44A1,TRIO,ZBTB14,GDPD5" Drug 6794_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADCY6,ADRA1B,AGT,MARK4,CFLAR,CA4,HAP1,CCK,JAKMIP2,PARD6A,EGFR,REEP2,FHL1,TDRKH,CACFD1,TJAP1,KCNN1,MID1,SETD4,ZSCAN2,KCNIP1,SBF1,NLGN1,SMARCD3,LIMCH1,SNCA,TSPYL2,ARHGEF9,WSCD1,CHST8,GPR161,ZNF34,FAM155A,PLPPR2,SEMA3B,KCNAB1,ITM2C" Drug 3749_DN Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AMPD3,APC,ALDH7A1,NRP2,ST3GAL5,ASIC3,ARMC8,SLITRK5,ZNF337,DAPK3,ANKMY1,ELOVL5,INPP5B,ITPKA,MAPT,CNOT4,SLC11A2,RETREG1,PPARA,TCP11L1,ATXN7,SCN8A,ST6GAL1,DZIP1,FAM214B,SMARCD3,ARHGAP26,ATP10B,KIAA1107,SMG6,RPGRIP1L,TNS2,DNAH7,THRA,TNS1,VLDLR,DPF3" Drug 4228_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "TRMT9B,APBB2,APC,ADGRB2,LHX2,RAB26,EGFR,MTSS1L,ST3GAL6,DISC1,SEPT9,RUNDC3A,GPR75,LPAR4,SCIN,KCNN1,MAPT,MBD1,AFF1,CNOT4,NPR2,PLXNB1,PTPRB,FRMPD1,PPP4R3A,FAM214B,DOK5,UNC5B,IQSEC2,SS18,ZEB1,TRIM2,TNS2,OSBP2,SPHK2,KCNAB1,PHTF2" Drug 4990_UP Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADCY6,ADRA1D,TRMT9B,APC,ALDH7A1,CACNA1I,BAIAP3,NRG2,SPOCK2,MBNL2,ELN,MTSS1L,NRN1,ALDH1L1,GCNT2,SRCAP,LPAR4,PCLO,SOX21,LAMA2,AFDN,TAGLN3,MYO7A,MYT1,NELL2,MAPK7,KHDRBS2,NEK11,RPS6KA2,SCN2B,CNKSR2,PREX2,PLCB1,ADGRL3,TBCEL,PARD3,TIGD6" Drug 3000_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C3orf14,TRMT9B,APBB2,CDK13,ATP2B2,AZGP1,NRP2,SLC16A4,SOCS6,BRINP1,MBNL2,RASGRP2,MTSS1L,FGFR1,PDLIM5,SIGLEC8,SEPT9,LILRA2,CACFD1,SLC2A6,MAP4,TCP11L1,MAP6D1,CLIP1,MRAS,SH3BP2,SNAP25,ZHX3,KIAA1107,TPM1,TRO,SH3GLB2,KCNAB1,PCBP4,FAM13C,AAAS,JPH3" Drug 3774_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "TRMT9B,SEMA7A,APAF1,RASL11B,ATP2B2,KIF1A,CACNA1G,CFAP410,MTSS1L,NCALD,AGAP2,SIGLEC8,GNAL,GNAO1,MCHR1,IRF8,MMP16,MMP17,MX1,GPR85,PFKFB4,MTRF1L,PLXNB1,PPP2R2B,PTH1R,PTPRH,RASGRF1,SH3BP2,PKNOX2,SLC11A1,SNCA,LMO3,THSD1,PLCB1,SYP,MCF2L,MKRN3" Drug 1436_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "WASF1,CAMK2B,RUNX1T1,RCBTB2,CHN2,CNTN1,DAPK1,NR1D2,FEM1B,KCTD3,EPB41L2,STX2,OLFM1,PRKAG2,AFF2,ATP2C1,OGA,ERAP1,NELL2,CNOT4,STRN3,PPP2R2B,CNNM2,PTPRN2,TTC13,RNASEL,GALNT10,ELMO2,ZHX3,SPART,SS18,TCF4,ZMAT3,TMPO,HIRA,XRCC4,SLC17A7" Drug 2625_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADCY6,ADD2,LTBP4,KCNAB2,PDE8B,SLC2A11,ATP6V0A1,ADAM23,CACNA1I,CACNA1G,STOML1,LY86,AKAP7,LRIG1,PDE4DIP,ELMO1,C3orf18,FCGRT,ZNF589,IQCG,PCDH17,RASSF8,MAP4,NCF2,NELL2,NF1,NTRK3,SLC25A23,PTN,TRIM68,PKNOX2,KIF13A,ZC3H13,IQSEC2,ST5,PARD3,SMIM8" Drug 2890_DN "Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,EP400,BCL7A,ST3GAL5,ENTPD4,ABCG1,CSNK1E,IRAK4,PCOLCE2,ENO2,EZH1,DISC1,GSN,INPP5B,ITPKB,MAP4,MAPT,MBD1,SCAMP5,MPP2,ADAM22,SLC11A2,PRPH,CNNM2,TMEM104,RIPOR1,ZSCAN2,TMEM231,ANKRD6,ABLIM3,ELMO2,RBM34,THSD1,EXOC7,TRIM2,VGF,EMSY" Drug 2802_DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,ABHD6,APOC1,ARHGDIG,ATP6V0A1,CFLAR,CA4,AKAP12,SIPA1L1,GPRASP1,FBXL5,LYPD1,RCAN1,DTNA,TNK2,ENO2,ACSL4,KAT8,FECH,PDLIM5,DIDO1,HNMT,ITPKB,ZNF862,PDE4A,PRPH,ZSCAN32,PTPRE,NKAIN1,NEK11,DHX30,COA1,VPS13A,PLCB1,TACC1,DMXL2,EPM2A" Drug 4390_DN Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AMT,EP400,KCNAB2,APC,NUMB,CA4,CAMK2B,ARHGEF1,ARHGEF2,MAGI1,CLGN,SOCS6,QKI,AKAP7,CREM,ABCG1,POLL,IL6ST,MAPT,TM6SF1,KITLG,CNOT4,MINDY2,GRAMD1C,ZSCAN32,LIMCH1,ZHX3,TRIM2,SZT2,CRTC1,PCDHA6,SLC44A1,CDK20,HIRA,VLDLR,EMSY,ST7" Drug 5703_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "FZD9,TRMT9B,AMH,BIN1,CDC42BPA,PPP4R4,SLC4A4,ST3GAL5,CA4,CBFA2T2,VAX2,SIPA1L1,CTH,DAPK3,MTSS1L,STX2,IQCG,USP19,PCLO,CNTRL,IL6ST,MAP2,AFF1,PDE4A,DCUN1D2,SBF1,SH3BP2,ZHX3,KDM4C,ZNF423,TSPYL2,EXOC7,TBCEL,ZEB1,AMACR,ZBTB14,EVI5" Drug 5756_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C1QTNF3,KCNAB2,ALDH7A1,SCAPER,CA8,LARGE1,CSF1,DZIP3,LYPD1,EIF4G2,FGF1,GLYR1,KCNMB4,PCLO,DHX35,IL12A,KCNH2,MAPT,MIA2,ZNF862,NDP,MBOAT7,PPARA,MAPK7,GSTCD,SH3BGR,LIMS2,THSD1,COBL,SZT2,GPR161,BHLHB9,TNS1,XRCC4,HPS4,EPM2A,ACTR3B" Drug 309_UP sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ARRB2,DNAH17,EIF4G3,NRP2,MTMR3,DBI,DBN1,DTNA,EPB41L2,FGFR1,DCTN2,B4GALNT1,BTN2A1,KHK,KIF5A,STMN1,MAP4,MAPT,PTOV1,NFYA,NPR2,SETD4,ENPP2,RETREG1,PLCD1,RIPOR1,GAL3ST4,CASC3,FNDC3A,ST6GAL1,TROVE2,CLSTN2,IQCE,TNS2,CRTC1,TRIO,SLC17A7" Drug 6134_UP Ronidazole [7681-76-7]; Up 200; 20uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ATP2B2,ADGRB2,SYNJ2,MTMR3,MYRF,HIP1R,CDH2,SULT4A1,FAM149A,USP6NL,SV2B,EDIL3,EGR3,EIF1,NXPH3,ICA1,TJAP1,KCNJ5,MYT1,CLDN11,TREM2,PFKFB4,SERPINI1,PLTP,EMID1,RPS20,SLC9A5,SNAP25,KDM4B,DOP1A,HECW1,DDN,EXOC7,WSCD1,LMF1,SPHK2,SLC17A7" Drug 6462_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "KCNAB2,PDE8B,RGS11,CFLAR,ARHGEF7,KALRN,CD86,CBFA2T2,WHRN,SPOCK2,HS3ST2,FAM13A,ERAP1,KCNJ5,KIF5A,LAMA2,MMP16,MSI1,SLC25A23,PLTP,LRP12,PRKAR1B,MAPK10,SAMD9,RGS12,ASAP3,SLA,COA1,SNAP25,KIF13A,HECW1,PEG10,PCDHA5,AP4E1,VSNL1,NT5M,EPM2A" Drug 457_DN tetraethylenepentamine pentahydrochloride; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NDRG2,BEGAIN,EPB41L5,GAS7,ST3GAL5,GYG2,LY86,ENTPD4,AATK,KIAA0753,OPTN,F5,HPCAL4,FAM49B,GPR37,ADAM22,CNOT4,PLCD1,PRKAR1B,KLK6,SUSD4,RASGRF1,GAL3ST4,RET,R3HDM2,KBTBD4,SMARCC2,FNBP1,ZHX3,ZC3H13,SPART,EXOC7,IQCE,METTL3,REEP1,SLC17A7,FIP1L1" Drug 2174_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,NDRG3,AP2A2,MTUS1,AMT,APOC1,NCOA1,KIF1A,SYNJ2,CLGN,RCBTB2,SOCS6,RAB28,SH2B1,PDE4DIP,CST3,SLITRK5,SPATA2,FRY,ING4,TNK2,EIF1,RASGRP2,CD320,ZNF589,PRKAG2,HNMT,SMAD1,GIT1,NINJ2,CEP68,KANK1,PDLIM2,TK2,TLR4,TNS1,UPF3A" Drug 5107_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "PKP4,KCNAB2,APBB2,ADAM23,MAGI1,ARHGAP22,SH2B1,ABCG1,SLITRK5,FAM131B,TM9SF4,MFAP3L,RUSC2,DTNA,MRNIP,COQ7,PTK2B,ST3GAL6,BAIAP2,RUNDC3A,GNAL,SPACA9,CNOT4,NPR2,PCBP3,MINDY2,LRRN3,PTPRH,RGS12,RPS6KA2,SLC4A3,KDM4C,ARHGAP26,SPTB,ZBTB43,TK2,EPM2A" Drug 6618_DN Protoveratrine A [143-57-7]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NME5,AMT,APBB2,CDK10,KSR1,ST3GAL5,SYNJ2,WHRN,CSNK1E,DZIP3,AASS,ZNF549,SCARA3,ZNF44,TRAF3IP2,CNTRL,SHISAL1,INPP5B,MAN2A2,MAPT,AFDN,NF1,SLC25A23,FAT4,BEND5,GSTCD,ATXN7,ZNF821,AMBRA1,ANKRD6,ELMO2,LHPP,TK2,TNS1,RPRM,NDRG4,SMIM8" Drug 5395_UP Aminophylline [317-34-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADRA1D,LTBP4,ALK,BEGAIN,CDC14B,MPDZ,ST3GAL5,CAMK2G,CHN2,WHRN,GREB1,RIMS2,DTNA,DTNB,EGR3,TENM1,COQ7,FHL1,PRRC2B,HLF,KPNA5,MID1,MYT1,NNAT,NTRK2,MTRF1L,MAPK10,PKNOX2,DOK5,ATP10B,ZC4H2,VPS13A,SMG6,TCF4,LAT2,SPHK2,ADAMTSL3" Drug 405_UP tetraethylenepentamine pentahydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,NDRG2,APBB2,GAS7,CFAP410,HAP1,CAMK2G,SCARB1,SLIT2,LY86,CNTFR,SPATA2,DPP6,DRP2,RCAN1,E2F5,SRPK3,FGFR1,POMT1,GRB10,NNAT,ENPP2,RETREG2,PPP3CA,CEP41,PTPRN,C1orf109,TCP11L1,SLC11A1,SNCA,KDM4B,ANKRD28,TRIO,UBE3A,KCNAB1,MPPE1,AAAS" Drug 3869_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,AK2,APBB2,FAM131A,CDK13,NECTIN3,ARHGEF4,HDAC4,DTNA,PHC2,HSD17B14,COQ7,ERCC2,KAT8,GCNT2,SRCAP,POLL,ELOVL5,KCNH2,LMO2,MBD1,KITLG,NF1,LRP12,MBOAT7,NKAIN1,KIF13A,KDM4C,STX1A,MCF2L,EXOC7,KIAA1107,SMG6,CHST8,SLC44A1,PLPPR2,EPM2A" Drug 1542_DN Paclitaxel [33069-62-4]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "PPFIA3,CAMK2G,TMCC2,DNM1,RCAN1,IRAK4,COQ7,ANKMY1,FER,BAIAP2,FAM49B,INPP5K,GLYR1,RAB30,GNG4,INPP5B,MBD1,NEK1,NFYA,MBOAT7,FSD1,APTX,RGS12,FAM192A,ZNF821,FBXO11,PPP4R3A,EPN2,ZBTB43,POGZ,PLCB1,AP4E1,ZNF34,SPHK2,REEP1,EPM2A,ST7" Drug 2153_UP Sulmazole [73384-60-8]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADD2,CDC42BPA,GYG2,THSD7A,CLGN,TAOK2,CRY2,CSF1,PHC2,HIPK3,EIF1,STX2,FGFR1,DENND2A,SESN1,NXPH3,DHX35,LSS,MAP4,ZNF862,PFKFB4,PLEC,RIPOR1,ZMAT4,RFX2,SMARCD3,ZC3H13,TBCEL,SYNE1,SLC35G2,HIF3A,MKRN3,SPHK2,EMSY,PCBP4,FZD3,MARCH8" Drug 1747_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABR,CDK10,ARNTL,SCAPER,MTMR2,HIP1R,AKAP7,SEC31B,SPOCK2,DCTN1,DPH1,ING4,EPB41L2,ZNF589,TRMO,PRRC2B,LILRA2,PTPRT,KCNN1,KHK,GIT1,PLCB2,POLR2F,PRPH,SAFB,ATXN2,SH3GL3,AMBRA1,NSFL1C,VPS13A,OBSL1,TMPO,KAT6B,UBE3A,NPDC1,ZNF24,GDPD5" Drug 6478_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADORA1,CDC42BPA,SLC4A4,SCAPER,CFAP410,KALRN,WHRN,LRIG1,ARHGEF10,PDE4DIP,EDN3,EGR3,DENND2A,GALC,INPP5K,SRCAP,LPAR4,SMAD1,MAN2A2,OPRL1,SLC25A23,LRP12,PPP2R2B,ASAP3,ST6GAL1,FAM214B,SNAP25,FAIM2,PDZD2,HECW1,SS18,TRIM2,TNS1,TRO,VSNL1,SLC30A3,EPM2A" Drug 4562_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADD2,ALK,KCNAB2,APBB2,APC,CDC14B,PDE8B,KIF1A,CACNA1I,NRXN3,AKAP7,NCOR2,MFAP3L,TENM1,HSD17B14,CDKL3,SRCAP,SPACA9,HLF,KIFC3,GIT1,MT1M,MYO7A,CNOT4,NTRK2,CLDN11,PRKAR1B,SAMD9,FBXW7,RPS6KA2,ST6GAL1,PHLDB1,SLC44A1,AMACR,RPRM,NDRG4,KCNAB1" Drug 3402_UP Primidone [125-33-7]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NME5,SYT13,APOC1,CACNA1I,CHRNA4,CLTB,CPS1,SNCAIP,ARHGEF10,SPOCK2,DBT,RUSC2,EXOG,DUSP9,FRY,PLXNC1,HSD17B14,LRRC17,ERCC2,REEP2,CAMKK2,DLL3,NEU3,GNAO1,C2orf72,PCBP3,CLDN11,LRP12,C19orf57,TSNAXIP1,ARC,WSCD1,THRA,PARD3,TRO,TRPM2,EPM2A" Drug 7552_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "CFLAR,CA12,CAMK2B,KYAT1,RAB33A,CLCN3,QKI,HOMER3,ARMC8,NCOR2,CSNK1E,JAKMIP2,DTNA,FCF1,ZNF589,OGA,GNG4,NXPH3,TJAP1,IL6ST,KCNN1,MIA2,LRP12,RIC8B,TCP11L1,FBXO11,ANKRD6,CCDC88A,BTBD7,SNCA,SP4,STX1A,ZKSCAN5,VIPR2,TFIP11,FIP1L1,SMIM8" Drug 3073_DN Flucytosine [2022-85-7]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C1QTNF3,CDC42BPA,APAF1,SCAPER,HIP1R,B4GALT6,PDE4DIP,PLXNC1,EIF4G2,EIF1,VPS13B,PDLIM5,GPD2,PCLO,N6AMT1,NINJ2,PLTP,CNTLN,PTN,BEND5,RXRA,SEC14L1,FAM214B,TMCC1,ZHX3,SPTAN1,CDK19,KANK1,ADGRL3,TBL1X,FLRT2,PLPPR2,XRCC4,MKRN3,PRDM10,UBE3B,NLRP3" Drug 5820_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,ADD2,MTUS1,PTCH2,ATP1A3,ATP2B2,AP4M1,QKI,CPS1,ENTPD4,ARHGAP24,ZNF337,GIT2,TAGLN3,MX1,PFKFB2,PIK3R1,PPARA,PPP5C,RASGRF1,KHDRBS2,GAL3ST4,RGS12,FNDC3A,ELMO2,IFT122,TMCC1,KDM4B,TBCEL,DOCK9,TNS1,VGF,KCNAB1,SMIM8,PHTF2,DPF3,RNF146" Drug 418_DN haloperidol; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ACADM,CDC42BPA,AQP6,ARNTL,HIP1R,TBRG4,PLEKHB1,RIMS2,E2F5,ETV1,TAOK3,KAT8,FAM49B,CAMKK2,ZNF44,ZNF276,LAMP2,MBD1,NFYA,SUSD4,SHMT2,CDK5RAP2,USP33,NMNAT2,CDK19,COBL,TRIM2,TRIO,SSBP2,VIPR2,XRCC4,SPHK2,ZNF189,ZNF195,GDPD5,MPPE1,AAAS" Drug 1780_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADORA1,C1QTNF3,SPOP,ARHGEF1,ARHGAP33,FAM189A2,BRINP1,DCTN1,MBNL2,RASGRP2,F5,PRKAG2,GLYR1,GRIK5,PADI2,MYO9A,NINJ2,OCRL,PALM,RETREG1,DEF8,PTK2,ZNF671,AMBRA1,SLC6A8,SLC11A1,KBTBD4,MAPKBP1,SPTB,THSD1,SS18,TNS1,TSC2,LAT2,ZNF142,MPPE1,ST7" Drug 6239_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "CDC42BPA,APBB2,EPB41L5,MADD,CASK,CFLAR,SCARB1,SOCS6,AKAP12,ARHGEF10,PPP6R2,ZNF337,GIT2,DBN1,POLR1B,SEMA4D,DISC1,HSF2,L1CAM,MAP4,NCAM2,SETD4,PLXNB1,CNNM2,DCUN1D2,FNDC3A,PEX26,KBTBD4,TMCC1,KDM4B,ANKRD28,BEX4,KAT6B,SSBP2,HIRA,RPRM,LMF1" Drug 7081_UP PHA-00846566E [724718-26-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BRAP,AK2,AMPD3,STX16,ALDH7A1,BMP7,GYG2,SGCE,CAMK2B,CBFA2T2,SCARB1,ARMC8,PDE4DIP,FEM1B,EFCAB2,PDLIM5,OGA,SRCAP,STON1,ATXN2L,IL6R,MAP4,MMP17,GIT1,MX1,NNAT,PDPK1,PPP2R2B,PRPH,FAM184A,FBXW7,SUPT20H,IQSEC2,KAT6B,CABIN1,HPS4,ST7" Drug 7548_DN DNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,APBB2,CDK10,ATP2A2,ATP2B2,ARHGEF2,PLEKHB1,TPP1,SULT4A1,HOMER3,NCOR2,PDE4DIP,SPOCK3,DTNA,TENM1,ZNF589,CGREF1,ATXN2L,MATN3,NF1,NFYA,NPR2,CDK18,PLXNB1,PPP5C,PID1,RGS3,NEK11,SUPT20H,AMBRA1,DDN,JMJD6,ARHGEF9,COBL,UGT8,ZNF45,EPM2A" Drug 2476_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ALK,PTCH2,ATP2B2,KSR1,CAMK2B,ARHGAP33,CDO1,NRG2,CREM,RIPOR2,FLT1,SOX21,SCIN,KIT,MAP4,MAPT,AFDN,MYCN,NINJ2,NOVA2,CCSER2,PLEC,PPARA,LRRN3,MAPK10,KLK6,KCNIP1,SLC11A1,SNCA,HECW1,SPTAN1,ATP10B,SYNE2,PLCB1,LMF1,VSNL1,JPH3" Drug 6355_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADD1,APOC1,CFLAR,QKI,WHRN,DBT,EDNRA,FEM1B,FCGRT,BAIAP2,FAM49B,USP19,MSL3,GNG4,PRRC2B,GUCY1B1,IL6ST,L1CAM,MATN3,MYO6,SMOX,LRP12,MBOAT7,FSD1,CEP97,FUZ,FAM214B,BTBD7,ZBTB43,DDN,SS18,TK2,TNS1,HIRA,NDRG4,SH3GLB2,MAP3K12" Drug 2270_DN Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASIC1,SEMA6A,AMPD3,FAM131A,RASL11B,ALDH7A1,GYG2,RCBTB2,FOXN3,SLIT2,CNTN1,PARD6A,MBNL2,ACSL4,FGFR1,GLYR1,MSL3,GRIK5,GSN,ELOVL5,IL6ST,LIG4,TM6SF1,PLCD1,KLHDC8A,TCP11L1,SBF1,ZNF821,TRA2B,FBXO11,MAPKBP1,PLCB1,TACC1,TBL1X,KAT6B,MPPE1,EPM2A" Drug 4633_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ALK,APC,KSR1,THSD7A,HAP1,PLAA,TPP1,PDE4DIP,DBT,HIPK3,FCF1,ETV1,PDLIM5,FYB1,SIGLEC8,CSDC2,GLYR1,GNG4,LPAR4,HLF,IL6R,JAK2,AFF1,P2RY13,KCTD15,CNKSR2,ANKRD6,KANSL3,SLC11A1,SNCA,ZHX3,PEG10,ARHGAP26,PHLDB1,MCF2L,FBXW11,PHTF2" Drug 6629_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C1QTNF3,ALK,APAF1,DDO,BMPR1B,GYG2,AKAP5,C2CD2L,EDIL3,IRAK4,COQ7,ZNF391,REEP2,ZMYND10,BAIAP2,DCTN2,FAM49B,PRELID3A,TMEM8B,KCNJ5,CNOT4,PALM,PCDH9,PFKFB2,RETREG1,RAD51D,KCTD17,CCDC102B,ASAP3,PPP4R3A,OGDHL,PHLDB1,MCF2L,OBSL1,THRA,R3HDM1,DPF3" Drug 6496_DN Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BIN1,APBB2,APLP1,BCAS1,PPFIA3,ATP2A2,RIPK1,GYG2,SPAG9,NFS1,CACNA2D2,CREM,GIT2,DBT,JAKMIP2,CDON,CINP,MALT1,HNMT,MAP4,SLC11A2,MBOAT7,ELOVL2,RIPOR1,EMID1,SAFB,ZNF821,ELMO2,ZBTB43,CLASP2,TTBK2,ASTN2,EXOC7,SSBP2,HIRA,PLPPR2,TIGD6" Drug 6682_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,ACHE,LTBP4,EPB41L5,CFLAR,BAIAP3,CCNT1,CPS1,NCOR2,PDE4DIP,DLC1,FGFR1,EFCAB2,SRCAP,GSN,VSIG4,ELOVL5,JAK2,KIT,ADAM22,MSR1,MYCN,NTRK2,CLDN11,PDE4A,PDE4B,PPP2R2B,PTN,KHDRBS2,PNMA8A,TCP11L1,RASA3,FRMPD1,ZNF334,SNCA,ARHGAP26,ARC" Drug 2315_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "SYN3,ADORA2A,GAS7,SEMA4G,ADAM15,CAMK2B,KCNAB3,LHX2,TPP1,RASSF2,SPOCK2,JAKMIP2,DTNA,HIPK3,ELN,VPS13B,ZNF589,FGF12,FGFR1,FHL1,FOXF2,GLYR1,RASSF8,ITPKA,TAGLN3,NTRK3,PLCD1,PLTP,MAPK10,PTH1R,ZSCAN2,SH3GL3,PKNOX2,CCDC88A,SLC9A5,ZNF423,VIPR2" Drug 2257_DN Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,SRPX,BIN1,GAS7,DNAH17,RASL11B,BCL7A,CAMK2B,CAMK2G,SH2B1,MFAP3L,NR1D2,DTNA,PLXNC1,TNK2,RGS17,MSL3,GNG4,ELOVL5,MAP4,MAPT,MMP16,ZNF862,MINDY2,MAPK7,PTCH1,RIPOR1,ZNF821,ANKRD6,SZT2,TPM1,TRIO,RUNDC3B,VGF,KCNK12,MPPE1,TIGD6" Drug 5928_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABR,MTUS1,C1QTNF1,LTBP4,APBB2,CDK10,ASIC3,ARHGAP22,SMARCAL1,DUSP9,EDNRA,ING4,STX2,SCML2,ANKFY1,PRELID3A,TMEM8B,TXNL4A,POLL,GPER1,BACH2,HNMT,KHK,MAPT,PLCB2,PPP5C,BEND5,GTDC1,KIF16B,DDN,NXT2,ARHGEF9,TNS1,TRIO,VGF,WIPF1,SMIM8" Drug 4592_UP Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADGRF5,GAS7,NRP2,CACNA1I,RUNX1T1,ARHGEF2,CRLF1,CLTB,LY86,FAM149A,AKAP5,PDE4DIP,PLPPR4,EDNRB,ST3GAL6,SEMA4D,AFF2,PDLIM5,ZNF44,TMEM8B,GPD2,GPER1,JAK2,LSS,RETREG1,PPARA,PRKAR1B,PTPRB,ZCWPW1,HKDC1,SLC12A4,IZUMO4,TACR1,TRO,WIPF1,ZNF74,ZNF225" Drug 7311_DN Tiletamine hydrochloride; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "CDK13,ATP2A2,BID,SCAPER,ARHGEF2,CNOT8,QKI,NCOR2,CSNK1E,HDAC4,ARMCX2,LYPD1,PARD6A,FEM1B,MRNIP,EFCAB2,CINP,COPS8,CNTRL,HNMT,FAM69A,MX1,NF1,SLC11A2,FSD1,SNRK,CCDC88A,SMARCC2,ELOVL4,STX1A,DNMBP,SZT2,CABIN1,TNS1,ZKSCAN5,NAV3,SMIM8" Drug 6458_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABHD6,SEMA6A,APBB2,CDC14B,PLA2G4C,MARK4,ST3GAL5,CACNA1I,CACNA1A,SEPT7,CNTNAP2,GREB1,TMCC2,DTNA,EPB41L2,SCML2,FHL1,MSL3,INPP5B,NELL2,NF1,SLC11A2,P2RY1,PPP5C,ELOVL2,RIPOR1,ATXN2,ABLIM3,SIRT2,DOK5,ARC,TBL1X,VAV1,MAP3K12,HPS4,SEMA3B,PCBP4" Drug 5066_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AMH,AMPH,APAF1,ADAM23,GYG2,BAIAP3,IL33,PDE4DIP,RIMS2,DTNA,EDN1,NCALD,FGFR1,DCTN2,ALDH1L1,CSDC2,LYVE1,RUNDC3A,LPAR4,KCNF1,KCNJ5,LAMA2,ADAM11,NF1,NOVA2,PALM,GDPD2,CCDC40,ZCWPW1,RGS12,SCN2B,SLA,PKNOX2,KLHL4,VSNL1,ZNF74,SEMA3B" Drug 4982_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "APBA2,FAM131A,CDK13,MTMR3,HOMER3,CRY2,CSF1R,CSNK1E,EXOG,EDIL3,PIPOX,CAMKK2,ALDH1L1,USP19,GLYR1,GPER1,KCNH2,KIT,KPNA5,MMP16,NNAT,PCBP3,PLEC,PLXNB1,PPP5C,PRKAR1B,ELOVL2,CCDC40,KLHL11,RNASE1,EMID1,FUZ,TSPYL2,TBCEL,PCDHA5,WIPF1,HPS4" Drug 3928_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABHD6,CDC14B,STX16,SYNJ2,CFAP410,USP2,CACNA2D2,QKI,CNTN1,SH2B1,RIMS2,DTNA,FCF1,VPS13B,VPS26C,FER,FGFR1,PDLIM5,GPD2,PCLO,ACOT7,HSF2,INPP5B,KCNN2,MAPT,ADAM22,PLCD1,PRKAR1B,EPN2,KDM4B,SS18,NXT2,ST5,ARC,EXOC7,BEX4,PHTF2" Drug 5099_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADD2,CDC14B,SEMA4G,SLC4A4,KIF1A,CFLAR,ARHGEF7,FUBP1,MYRF,LARGE1,TAOK2,ARMC8,CREM,CSNK1E,PDE4DIP,DCAF4,DAPK3,FAM13A,HSD17B14,ETV1,FGFR1,BAIAP2,SEMA4D,B4GALNT1,GLI2,IL12A,LSS,KCTD15,FAM184A,RGS4,GSTCD,FBXW7,ZFP30,ZNF415,RBM34,PHLDB1,SYN2" Drug 4806_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,NME5,GAS7,PPFIA3,ARHGEF7,CACNA2D2,WHRN,CREM,ENTPD4,CRY2,SGSM2,COQ7,TPK1,AHDC1,USP19,CACFD1,HSF2,LMO2,MITF,GIT1,NTRK2,PLXNB1,SAMD9,RGS12,ATXN2,TSNAXIP1,ARHGAP26,SPTAN1,ZBTB43,TROVE2,ARHGEF9,KIAA0930,TRIM2,SZT2,AP4E1,SLC44A1,KCNAB1" Drug 5686_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASIC1,APAF1,APBA2,APOC1,CDC14B,SYNJ1,SYNJ2,CACNA1G,HAP1,FOXN3,CRY2,PDE4DIP,RIPOR2,RASSF2,ECM2,EGFR,MBNL2,FHL1,EFCAB2,SRCAP,RUNDC3A,TJAP1,MYT1,NTRK2,POU6F1,PTPRB,EPN2,ARHGEF40,SLC11A1,CXXC4,SOX11,ZBTB43,DICER1,TIMP4,ZNF711,EMSY,KCNAB1" Drug 6069_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "SYN3,ADD2,FZD9,ADORA2A,ALK,BIN1,RGS20,ATP1A3,DCAF4,CYBB,SPOCK2,KIAA0319,DTNB,SEMA3D,FYB1,ZNF44,GPR75,HAS2,ATXN2L,LAMA2,MGAT3,MSR1,TAGLN3,P2RY1,PPARA,KHDRBS2,RGS12,SLC2A5,ARHGEF40,CXXC4,PHLDB1,TCF4,CRTC1,FLRT2,DNALI1,ADAMTS9,KCNAB1" Drug 5436_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADORA1,BIN1,CDC42BPA,SEMA7A,APBA2,SEMA4G,PLA2G4C,AZGP1,SYNJ1,CDH2,SOCS6,VAX2,CREM,DBT,MFAP3L,SPOCK3,SLC12A6,HIPK3,EGFR,AASS,STX2,PDLIM5,LYVE1,RUNDC3A,MCHR1,KIT,MAP4,ADAM22,TAGLN3,PCDH9,PLTP,FBXO11,ANKRD6,FAM214B,SNCA,ZC3H13,UCHL1" Drug 3047_UP Nizatidine [76963-41-2]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABHD6,SPARCL1,RGS9,FUBP1,CACNA1G,NRXN3,ABCG2,RAB26,RGS6,BRINP1,JAKMIP2,PARD6A,SLC12A6,PTK2B,ZNF589,CSPG5,SIGLEC8,SEPT9,GPD1,PDE1C,ABCB1,SMOX,PURG,MAPK7,DCHS2,RGS4,SEMA6D,CNKSR2,FAIM2,SPTB,SYT1,ASTN2,TACR1,FAM189A1,DICER1,KLC2,SLC17A7" Drug 6221_DN Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "SYNJ2,KYAT1,CTH,PPP6R2,GIT2,SGSM2,FGFR1,FHL1,AHDC1,LIG4,MAP4,MAPT,MIA2,MITF,GIT1,NCAM2,NFYA,NPR2,OGG1,PCDH9,PDE4A,SMIM7,FA2H,CNNM2,RIPOR1,RPS6KA2,SUPT20H,ZKSCAN3,ELOVL4,ANKRD12,TBL1X,NSD1,TIAM1,PARD3,RPRM,VAV1,ZNF23" Drug 5864_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "CDK13,MYRF,CA8,SYNGR3,TPP1,WHRN,AATK,CSF1R,MFAP3L,KIAA0753,EGFR,TENM1,HSD17B14,RASGRP2,DLC1,ERAP1,SEPT9,ALDH1L1,TDRKH,MAN1B1,KHK,PACRG,PLCD1,PRKAR1B,TMEM231,FBXW7,KDM4D,SLC11A1,SNAP25,ATP10B,PCDHGB6,ZKSCAN5,LAT2,SPHK2,SLC17A7,PARP11,GAN" Drug 6941_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,CFLAR,SYNJ2,MTMR2,ARHGEF1,PLEKHB1,WHRN,LRIG1,PDE4DIP,DTNA,FCF1,OPTN,EPB41L2,DLC1,FER,SEMA4D,PDLIM5,GAD1,GRB10,MEIS1,NFYA,CDK18,LRP12,RETREG2,FAM184A,KCTD17,NEK11,NCBP3,MAPK12,SBF1,FERMT1,ZHX3,SPTAN1,SS18,EXOC7,TRIO,ZKSCAN5" Drug 5844_DN Folic acid [59-30-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,CDC42BPA,APC,PPFIA3,LRRFIP1,WHRN,SPOCK2,B3GAT3,RCAN1,COQ7,FGF13,SCARA3,DCTN2,TRMO,FYN,B4GALNT1,TMEM8B,DISC1,MAN1B1,DHX35,NFYA,NOVA1,PLCD1,MCMBP,SMARCC2,DDN,CLASP2,TROVE2,CAMTA2,VPS13A,DNMBP,TCF4,SLC35G2,PARD3,TRIO,AMACR,MAP3K12" Drug 5423_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,CDC42BPA,GAS7,CAMK2G,CBFA2T2,QKI,RCHY1,OSBPL3,ARHGEF4,RASSF2,DTNA,HIPK3,MRNIP,FECH,FHL1,AFF2,ADAM28,AP4S1,TJAP1,MMP17,NNAT,PDE1C,PFKFB2,LRRN3,RPS20,SCN8A,SH3BP2,ARHGEF40,ZHX3,UNC5B,SAMSN1,DOCK9,R3HDM1,FLRT2,NT5M,DNALI1,DPF3" Drug 6804_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "SEMA6A,CDC14B,MARK4,CFLAR,BAIAP3,CA4,NFS1,STOML1,CLTB,VAX2,CNTN1,RIMS2,JAKMIP2,STX2,REEP2,TDRKH,TJAP1,ITGAM,IPO5,MBD1,ZNF862,KLHDC8A,TCP11L1,EMID1,ASAP3,FAM214B,SLC11A1,SPTB,TROVE2,STX1A,ZNF34,UBE3A,UCHL1,VIPR2,WIPF1,SLC17A7,KCNAB1" Drug 6516_UP Tiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NME5,ADAM23,RGS9,VCAN,RASSF2,BRINP1,RCAN1,DTNA,HEYL,F5,CORO2B,ST3GAL6,FYB1,LPAR4,ITGA7,KCNN1,MGAT3,NF1,PDE4B,RETREG1,SAMD9,RNASE1,SBF1,FRMPD1,FAM214B,SLC11A1,RBM26,PLCB1,ARC,SMG6,PCDHA5,VIPR2,WIPF1,ZNF711,SEMA3B,KCNAB1,AAAS" Drug 389_UP wortmannin; Up 200; 0.01uM; HL60; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ARNTL,BACH1,WASF1,CA12,DLGAP1,PCYT1B,NCOR2,INTS1,GIT2,MAMLD1,FAM13A,ZNF391,BAIAP2,B4GALNT1,CACFD1,GRM8,BTN2A1,GUCY1A1,PADI2,MX1,NNAT,SLC11A2,OCRL,PRKAR1B,RAP1GDS1,DPF2,SATB1,FUZ,EPN2,SMARCD3,ARHGEF9,MCF2L,PARD3,VIPR2,NAV3,KCNAB1,MPPE1" Drug 1500_DN Tolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NDRG3,OSBPL1A,APC,ARRB1,CFLAR,BMP7,VAX2,ABCG1,GIT2,FBXL5,HIPK3,EZH1,KAT8,PDLIM5,TXNL4A,SLC2A6,CNOT4,NPR2,PLXNB1,PMP22,WDR25,CCDC25,FBXW7,FUZ,EPN2,KDM4B,SP2,ZNF423,SPTAN1,TROVE2,SYT1,MCF2L,TRIM2,PCDHA6,ZNF34,XRCC4,GDPD5" Drug 5421_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,LTBP4,APC,APOC1,DNAH17,MARK4,SYNJ1,SCARB1,LHX2,STOML1,SH2B1,RIMS2,TBC1D5,CNNM1,EIF5,ING4,ZNF589,OGA,SEPT9,AHDC1,RUNDC3A,SLC2A6,DHX35,KCNH2,MATN3,MIA2,ADAM22,SERPINI1,NLE1,PLXNB1,FSD1,PRKAR1B,RPS6KA2,ZSWIM8,UNC5B,TNS1,EVI5" Drug 6636_DN Harpagoside [19210-12-9]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "PPFIA4,APC,CDK10,CDK13,KIF1A,SYNGR3,TAOK2,HOMER3,WHRN,CPS1,CSF1R,MAMLD1,TUBD1,ETV1,FGFR1,ZNF44,INPP5K,POLL,HSF2,IL6ST,ITGA7,MMP16,NF1,PFKFB2,PPARA,GRAMD1C,FBXW7,ZNF821,DDN,SS18,RPGRIP1L,GPR161,PARD3,TPM2,XRCC4,EVI5,EPM2A" Drug 1229_UP clozapine; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AMH,SEMA7A,ARHGDIG,MARK4,BMP7,RAB33A,RAB26,AKAP7,TMCC2,ERCC2,STON1,GPER1,ICA1,TJAP1,MKLN1,ZNF862,NF1,OGG1,POLG,WDR25,TMEM231,RGS4,FBXW7,SUPT20H,SLC4A3,EPN2,BTBD7,SPTB,ARHGEF9,IQCE,TBL1X,TRIO,OSBP2,ZNF23,ZNF74,SEMA3B,PLSCR4" Drug 6685_DN Meglumine [6284-40-8]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "KCNAB2,MARCH3,CFLAR,SYNJ2,KRIT1,SOCS6,RAB26,ENTPD4,SLITRK5,RUSC2,SGSM2,NBEA,ATP2C1,CGREF1,TXNL4A,COPS8,POLL,PCLO,IL6ST,TM6SF1,PLCD1,LRP12,PTCH1,PTN,PTPRN2,TMEM231,MRPS18A,KIRREL1,AMBRA1,FBXO11,ST6GAL1,KIAA1107,HIRA,WIPF1,HPS4,NAV3,KCNAB1" Drug 3817_DN Ergocryptine-alpha [511-09-1]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,AP2A2,SEMA7A,EPB41L5,ATP1A3,SCAPER,PICK1,CSNK1E,CNTNAP2,ARHGAP24,DAPK3,DTNA,SUGP2,CDKL3,SCML2,FGF1,CSPG5,GPR75,GNG4,GPD2,DHX35,ITGA7,NLE1,RAD51D,C1orf54,KCTD17,RXRA,RASA3,OGDHL,SNCA,RBM34,DOK5,KDM4C,LHPP,TK2,TNS1,HPS4" Drug 6062_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,C1QTNF3,PPP4R4,ATP6V0A1,SCAPER,ARHGEF2,ARHGAP33,PICK1,CNTFR,AKAP7,BAG4,CSF1,PLXNC1,ELN,VPS13B,GAD1,GPR75,GRIK5,HNMT,KPNA5,MAP2,MATK,MMP16,ADAM22,NNAT,SLC25A23,RPS6KA2,ASAP3,COA1,HECW1,PHLDB1,PLCB1,RPGRIP1L,CHST8,TUBB1,WIPF1,PLSCR4" Drug 3011_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C3orf14,C1QTNF3,BIN1,NCOA1,ADAM15,NRP2,SYNJ2,SLC16A4,SCARB1,ARHGEF10,ZNF337,BRINP1,MBNL2,AASS,C3orf18,EFCAB2,SIGLEC8,AHDC1,ADAM28,LILRA2,GSN,SLC2A6,MAP4,MGAT3,AFDN,NINJ2,PTPRB,KHDRBS2,DDN,DOCK9,CDK20,TRO,LMF1,XRCC4,SEMA3B,KCNAB1,PHTF2" Drug 4600_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NME5,BIN1,ARHGDIG,ADGRB2,NRP2,BAIAP3,CBFA2T2,SYNGR3,MAGI1,PLEKHB1,HOMER3,CSF1,CSF1R,EDNRA,PRELID3A,MSL3,HLF,ITPKA,KCNN1,MX1,NOVA1,PDE4B,PIK3R1,PLXNB1,SAMD9,APTX,ZCWPW1,RPS6KA2,ZFP30,DZIP1,ZNF334,RPGRIP1L,VGF,VIPR2,WIPF1,LAT2,KCNAB1" Drug 5302_DN Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ABHD6,CFLAR,SCARB1,ARHGEF2,PLEKHB1,PLAA,ENTPD4,CTH,PPP6R2,DTNA,CELSR3,EZH1,ANKFY1,CACFD1,INPP5B,MEIS1,NACA,NF1,NPR2,OGG1,PCDH9,PPP5C,PRPH,ELOVL2,RNASEL,ROBO1,FBXW7,FAM192A,FBXO11,UNC5B,CDK19,TSPYL2,CLASP2,TRIO,ZKSCAN5,LMF1,TFIP11" Drug 3186_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,C1QTNF1,ARHGDIG,CACNA1I,BAIAP3,HAP1,RUNX1T1,EPS15L1,AKAP6,WHRN,MYRIP,MYEF2,DMPK,EDNRB,PIPOX,RASL12,BAIAP2,FHL1,FLNC,GAD1,NEU3,JAK2,KPNA5,MITF,MSR1,MYO7A,NECAB2,CEP41,RPS6KA2,IZUMO4,LMO3,SLC35G2,TIMP4,PIK3R5,CHST5,MKRN3,LAMP5" Drug 2530_DN Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NDRG2,ADRA1D,AMPD3,APC,MARK4,NCOA1,ADAM23,SYNJ2,MTMR3,CACNA1A,PDE4DIP,DAPK3,RHOBTB1,SPOCK3,TUBD1,VPS26C,FECH,CAMKK2,INPP5K,MSL3,PADI2,MAN1B1,ITGAM,MID1,NNAT,NLE1,LRP12,AMBRA1,FBXO11,KDM4B,KDM4C,DMXL2,ZEB1,THRA,TRIO,MAP3K12,FAM13C" Drug 2497_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BEGAIN,BIN1,CDC42BPA,PKP4,ARHGDIG,KIF1A,BCL7A,CACNA1I,FAM149A,NCOR2,ABCG1,HEPH,DTNA,ECM2,MBNL2,PLEKHA1,HSD17B14,RASGRP2,ERCC2,ZNF549,CDKL3,BAIAP2,CGREF1,ALDH1L1,GRIK5,IL6ST,KIF5A,MAP4,MAPT,NNAT,PDE4D,PFKFB2,PTPN13,FAT4,PLCB1,DICER1,PRDM10" Drug 2931_UP Tocainide hydrochloride; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BIN1,CDC42BPA,ANK2,APBB2,PDE8B,MYRF,TAOK2,HOMER3,CRY2,PHF14,DCAF4,TNK2,RASGRP2,STX2,TBC1D16,KAT8,GATM,RUNDC3A,ICA1,SCIN,KCND1,MYO6,ZNF862,NPTX2,PLEC,SLC25A23,PPARA,FAM102A,ANKRD6,PEG10,SPTAN1,TROVE2,SZT2,SLC19A3,TK2,TNS1,VGF" Drug 2359_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "FZD9,APBB2,DNAH17,KIF1A,RGS9,KSR1,SYNJ2,MTMR3,CACNA2D1,CAMK2A,MAGI1,AKAP7,SLITRK5,PPP1R16B,SGSM2,AASS,F5,MAPT,MGAT3,MYCN,NEFM,NF1,NTRK3,ENPP2,NLE1,PPARA,PTPRO,RGS3,MRAS,ASAP3,SNAP25,RBM34,SPTAN1,ZBTB43,SYT5,TPM1,CLIP2" Drug 1751_DN Stachydrine hydrochloride; Down 200; 22.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "OSBPL1A,EP400,PKP4,APAF1,BARD1,CFLAR,RCBTB2,GIT2,DENND4A,ATP2C1,OGA,ZNF44,PRRC2B,LAMP2,TRHDE,PPM1B,PRKAB2,C1orf54,RDX,CCDC25,PCMTD2,SUPT20H,TRA2B,CHD9,CCDC88A,ATF7IP,USP33,CLASP2,ITPRID2,NXT2,HIRA,UBE3A,EVI5,PDSS2,UBE3B,JMJD1C,RNF170" Drug 6394_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADD2,LTBP4,APOC1,ATP2B2,BACH1,CACNA1I,ARHGAP33,CACNA2D2,SOCS6,EPS15L1,TPP1,STOML1,AKAP5,CPS1,SPOCK2,ELMO1,SPOCK3,EGFR,AASS,TENM1,AFF2,FOLR2,ADAMTS13,HLF,KCNJ5,ADAM22,MSR1,MYO7A,NNAT,LRRN3,RGS4,UNC5B,SYN2,WSCD1,TRPM2,UCHL1,ITM2C" Drug 3638_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,BIN1,CDC42BPA,KCNAB2,APC,APOC1,GYG2,CACNA1I,BAIAP3,HAP1,CDO1,AKAP5,SNCAIP,SIPA1L1,CNTNAP2,DAPK1,MFAP3L,SHANK1,ZNF589,DLL3,GSN,DHX35,ICA1,KCNH2,ADAM22,NEK1,NPTX1,CDK18,RETREG1,CXXC4,DOK5,KDM4C,RPGRIP1L,CRTC1,SLC35G2,PIK3R5,ITM2C" Drug 6056_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,ASIC1,ALCAM,APBA2,KCNAB2,APOC1,SEMA4G,RGS20,NUMB,SYNJ2,USP2,SEPT7,SLC12A6,EDNRA,VPS26C,FHL1,PDLIM5,FYB1,HLF,KCNN2,SMAD1,MAP2,MMP16,NF1,NNAT,OXTR,SLC25A23,NKAIN1,RPS6KA2,ASAP3,ZEB1,TNS2,CRTC1,DICER1,TNS1,NPL,SMIM8" Drug 1907_DN Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADCY6,GAS7,EIF4G3,RIPK1,CFLAR,SLC25A14,CCNT1,CDH2,FOXN3,SUGP2,DLC1,TRMO,DLL3,DENND2A,GAD1,COPS8,GPR37,CACFD1,BTN2A1,MAP4,SCAMP5,MITF,NEK1,PDE1C,MBOAT7,MAPK7,SPDL1,SH3BP2,AMBRA1,SLC11A1,ARFGAP1,SMARCA4,RCOR3,NMNAT2,ZEB1,NACC2,TMPO" Drug 4157_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "KCNAB2,ARSE,ADAM23,RGS9,CAMK2B,RUNX1T1,AKAP7,WHRN,ELMO1,DMPK,HS3ST2,EDN3,MTSS1L,EPHB1,FGFR1,FAM49B,OGA,SIGLEC8,ALDH1L1,POLL,GRM8,ATXN2L,HLF,ITGA7,KCNH2,MID1,NPTX2,NTRK2,GPR85,CNTLN,PNMA8A,PKNOX2,SPTB,SYN2,TLR4,EVI5,DPF3" Drug 6007_UP Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "C1QTNF3,SRPX,LTBP4,SEMA4G,CFLAR,BAIAP3,CBFA2T2,RCBTB2,MYRIP,NRG2,DMPK,DTNA,VPS13B,RASGRP2,ZMYND10,ERAP1,ALDH1L1,GSN,ELOVL5,PURG,MAPK7,ZDHHC14,SBF1,RASA3,PPP4R3A,OGDHL,DOP1A,KDM4C,ATP10B,PLCB1,SYT5,TAL1,DMXL2,TRPM2,UBE3A,KCNK12,DNALI1" Drug 4348_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "NDRG2,ADD2,AP2A2,APOC1,MARK4,VCAN,DOCK4,EDN1,ELN,F5,FGF14,GFER,GNAL,GRB10,CACFD1,HLF,ICA1,MAN2A2,OGG1,PALM,PLTP,CNTLN,PTPRH,ZNF493,ST6GAL1,SYBU,SLC11A1,ZC3H13,RGL1,TBCEL,SMG6,ZEB1,TNS1,CHST5,UGT8,DNALI1,JPH3" Drug 5103_UP Sulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "MAP4K3,APC,BCAS1,SLC4A4,ADAM23,NRP2,ARHGAP33,SOCS6,CHN2,HOMER3,AKAP5,CRMP1,CSF1,DZIP3,DMPK,DTNA,COQ7,EPHB1,FGFR1,GRM8,SOX21,NTRK2,RETREG1,MINDY2,CNNM2,PTPRB,TMEM231,RGS12,ZNF821,FBXO11,BTBD7,GLT8D1,ARHGAP26,ASTN2,TPM2,LAT2,FZD3" Drug 5459_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BIN1,APAF1,APBA2,MPDZ,BAIAP3,HIP1R,EPS15L1,PLAA,EDNRA,HIPK3,EGFR,ELN,DLC1,ERAP1,GNAO1,PRUNE2,ICA1,KCNJ5,KCNQ3,MEF2C,MSR1,PDE1C,MTRF1L,MBOAT7,PTPRB,KCNIP1,FAM214B,KDM4B,PDZD2,DOK5,ATP10B,ARC,DOCK9,PLPPR2,WIPF1,XRCC4,HPS4" Drug 6353_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,EP400,APC,WHRN,ARHGAP32,INTS1,GIT2,ARMCX2,SPATA2,KIAA0753,ERBB2,SCML2,TRMO,CAMKK2,SRCAP,GUCY1A1,MAN1B1,SYNPO,KIF2A,MAP4,ZNF862,CLDN11,NCBP3,CSRNP3,FUZ,KBTBD4,SMARCA4,DDN,ARHGEF9,IQCE,WSCD1,CABIN1,TNS1,TSC2,ZKSCAN5,XRCC4,MPPE1" Drug 4448_DN trifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "AP2A2,APBB2,BMPR1B,SCARB1,NRXN3,CNTN1,SH2B1,CSF1R,GPRASP1,EXOG,FAM13A,SUGP2,EPB41L2,BAIAP2,PDLIM5,ATXN2L,KIFC3,MAPT,MEF2C,NDP,NF1,NFYA,PLCB2,PPP5C,WDR25,TRAPPC13,SAFB,ZNF821,SH3BP2,FBXO11,DZIP1,OGDHL,ARHGAP26,IQSEC2,TNS1,ZNF24,PHTF2" Drug 4284_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADRA1D,ALK,SYT13,KCNAB2,GAS7,N4BP2L1,BACH1,BMP7,BTK,CAMK2A,CD38,CSF1,VCAN,BRINP1,DBT,FYB1,HTATSF1,GRIK5,ICA1,LSS,KITLG,AFDN,ADAM22,NPTX2,PCSK1,MTRF1L,TMEM255A,EMID1,SH3BP2,FRMPD1,RBM34,NFASC,MCF2L,CUX2,VAV1,ADAMTS9,EPM2A" Drug 1863_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASIC1,OSBPL1A,APC,APOC1,DNAH17,NCOA1,KRIT1,SLC16A4,RAB33A,CLCN3,IQCK,ZFYVE16,GIT2,SGSM2,MRNIP,EIF1,ENO2,RASGRP2,ANKFY1,EFCAB2,N6AMT1,NF1,PIK3R1,CEP41,CNNM2,GSTCD,TRA2B,RASA3,TMCC1,CDK19,THSD1,ZC4H2,TBCEL,SIN3B,DICER1,TK2,BCL2L13" Drug 2363_UP Proglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "MTUS1,APBB2,SEMA4G,CDK13,BACH1,KSR1,BMP7,MTMR3,CD86,CDH2,CRY2,KIAA0753,C2CD2L,DTNA,MRNIP,FAM198B,PRELID3A,GATM,GPR162,GNAL,GPD1,SPACA9,HNMT,MYO6,ZNF862,NF1,PTCH1,RIPOR1,ZCWPW1,EPN2,BTBD7,IQSEC2,ZC4H2,KCNK12,EVI5,SLC17A7,SENP7" Drug 7461_UP Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "LTBP4,BEGAIN,AMPD3,PLA2G4C,MARK4,SLC4A4,SCAPER,SGCE,FOXN3,TPP1,AKAP5,CREM,ENTPD4,CRY2,MAML1,FAM198B,SRCAP,MALT1,RAB30,GPR37,SPACA9,MAP4,MAPT,MMP16,ADAM22,NEK1,NF1,SLC25A23,PLXNB1,POLG,RPS6KA2,SEC14L1,SLA,CXXC4,HECW1,THSD1,THRA" Drug 5876_UP Convolamine hydrochloride [500-56-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "RALGAPA1,C1QTNF1,DOC2A,CACNA1I,BAIAP3,CA8,CACNA1A,ARHGAP33,PICK1,ARHGEF10,DUSP9,EDIL3,RGS17,HSD17B14,PIPOX,CORO2B,DLC1,TMEM8B,SEPT9,ADAM28,GPR37,SCIN,KCNF1,KCNQ3,SMAD1,MAPT,PDE4B,ENOX1,DZIP1,FAM214B,ZHX3,ARHGAP26,ATP10B,ASTN2,REEP1,KCNAB1,DPF3" Drug 5496_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,C1QTNF3,PKP4,PPFIA3,CDK10,CFLAR,SCAPER,LRRFIP1,MAGI1,CNOT8,CREM,NCOR1,PPP6R2,MFAP3L,DCTN4,STX2,ANKMY1,DLC1,NOP56,OGA,ERAP1,INPP5K,KHK,MPP2,MYO6,ZNF821,SHMT2,FBXO11,SMARCA4,RBM34,STX1A,ANKRD12,ZNF34,PLPPR2,ZNF23,MPPE1,TIGD6" Drug 3687_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ADCY6,ALDH7A1,SCAPER,IL33,SYNGR3,PLEKHB1,LHX2,HOMER3,HAPLN1,NCOR2,DPH1,FGF1,TRMO,CINP,TRAF3IP2,SRCAP,GNG4,ITPKA,MAN2A2,MAPT,SCAMP5,ZNF862,CNOT4,CLDN11,RETREG1,PTPRB,CCDC40,SUPT20H,ASAP3,BTBD7,KIAA1107,AMACR,WIPF1,WNT7A,XRCC4,MPPE1,GAN" Drug 641_DN benserazide hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "APC,APOC1,ARHGDIG,MTMR2,CACNA1I,KALRN,SPAG9,ARHGAP33,CHN2,LY86,SEC14L5,HS3ST2,FEM1B,OPTN,EGFR,RGS17,SRPK3,TRMO,ZNF276,ADAMTS13,PRDM5,BTN2A1,ATXN2L,MBP,MMP16,NPR2,PLCD1,PTH1R,PTPRN,SUSD4,FUZ,KBTBD4,SPART,SLC19A3,UCHL1,VIPR2,WIPF1" Drug 3299_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ANK2,APC,APLP1,ST3GAL5,CFAP410,CAMK2G,SULT4A1,ARHGEF6,SNCAIP,PDE4DIP,DZIP3,SEC14L5,DOCK4,JAKMIP2,FECH,FGFR1,TPK1,CSDC2,POLL,GNG4,ATXN2L,HLF,ADAM22,PLTP,TMEM231,ZFHX4,CXXC4,ZC3H13,ST5,SYN2,KIAA1107,SYNE1,CHST8,GPR161,CDK20,RUNDC3B,DNALI1" Drug 6040_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "BEGAIN,DDO,CFAP410,CAMK2B,STOML1,WHRN,DOCK4,ARHGAP24,SPOCK3,ZNF589,OLFM1,FGFR1,BAIAP2,DCTN2,CAMKK2,ERAP1,SYNPO,IL12A,KCNN1,ENPP2,DUSP26,PRKCB,MAPK7,ELOVL2,PTPRB,ZMAT4,CARF,RPS6KA2,FRMPD1,FAM214B,PKNOX2,UNC5B,JMJD6,CRTC1,TLR4,TPM2,LAT2" Drug 4008_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "TRMT9B,GAS7,CNOT8,NRXN3,HOMER3,WHRN,SH2B1,CSF1,ARHGEF10,ARHGAP24,EGFR,MBNL2,AASS,ST3GAL6,CINP,ZNF276,LPAR4,GRM8,INPP5B,RETREG1,FA2H,FSD1,PPARA,MINDY2,PTPRB,FRMPD1,SLC9A5,SS18,TRIM2,DNAH7,GPR161,TK2,TRIO,RPRM,XRCC4,KCNAB1,TIGD6" Drug 6088_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.24E-02 1.40E-01 37 199 "ASPHD1,APBA2,KCNAB2,APBB2,SYNJ2,CA4,KYAT1,CBFA2T2,PLEKHB1,PLAA,QKI,NECTIN3,CSF1R,C2CD2L,DUSP9,PRELID3A,MUM1,RASSF8,PADI2,IPO5,MMP16,MSI1,MINDY2,PRKAR1B,CEP97,RGS12,SBF1,ANKRD6,SMARCD3,KDM4C,IQSEC2,THSD1,EXOC7,AP4E1,VIPR2,TFIP11,SEMA3B" Drug CID000000190 adenine Stitch 1.73E-03 1.00E+00 1.25E-02 1.40E-01 80 510 "ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,NME5,AK2,AMPD2,AMPD3,DPP10,APAF1,APC,NT5C3B,ALDH7A1,BCS1L,BLM,LDHD,P2RX6,CD38,ENTPD2,CRY2,GDA,CS,CYBB,SLC29A4,FCF1,ERCC2,GMPR2,FCGRT,MAD2L2,POLK,AK8,ZNF274,MTHFD2,GCK,NFU1,TXNL4A,LPAR4,IDH3A,IDH3B,MAP4,MAT2A,N6AMT1,P2RY13,NCF2,NFIX,NME4,OGG1,P2RX7,P2RY1,PKM,SLC25A23,TRHDE,POLG,PSMA6,QDPR,REV3L,RNASE1,NUDT11,RYR3,SHMT2,SIRT2,SNCA,SPATA7,NMNAT2,SPP1,ADHFE1,NUDT10,TBL1X,SMG6,NSD1,CYB561A3,SIRT1,SMUG1,NEIL2,HSPBP1,P2RY12,PRTFDC1,MSRB3" Drug CID000000823 glycerol-3-phosphocholine Stitch 1.75E-03 1.00E+00 1.26E-02 1.42E-01 33 172 "ACHE,ABHD6,PLA2G4C,PDE8B,ALDH7A1,CAPN3,CNTFR,PCYT1B,PLCXD3,ENPP6,GFRA2,MCHR1,PLCD4,IL6ST,LIFR,NTRK2,NTRK3,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PLCB2,PLCD1,GDPD2,RXRA,SMPD3,PLCB1,SGK3,GDPD5,PLD4" Drug CID000004591 AC1L1IIA Stitch 1.75E-03 1.00E+00 1.26E-02 1.42E-01 33 172 "AK2,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B2,BCHE,NAE1,CFAP410,CALM1,SLC25A14,ENTPD2,CDR1,COL4A5,CS,CYBB,DMPK,FKTN,AK8,ATP6V1H,ATP2C1,GATM,GCK,GPD1,GPD2,LSS,NPTX2,PFKFB3,ABCB1,DUSP15,S100B,TCEA1,CYB561A3" Drug CID000062276 lactofen Stitch 1.79E-03 1.00E+00 1.28E-02 1.45E-01 19 82 "APBA2,BTK,CACNA1I,CACNA1G,SPOCK2,WDR20,EXOG,FLT1,MEF2C,PCDHGC3,PDPK1,IRX1,COBL,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA2,TUBA1A" Drug ctd:C109476 epoxiconazole CTD 1.79E-03 1.00E+00 1.29E-02 1.45E-01 58 348 "ACTN1,DOC2A,DPP10,BID,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CAMK2B,CAMK2G,CARS,RGN,HECTD1,AHCTF1,NSL1,C2CD2,TM9SF4,DBT,DDX46,DPP6,EGFR,MBNL2,AASS,EIF4G2,ERBB2,ERBB4,PIPOX,F5,FGF1,VTI1B,FYN,GHR,STMN2,GRIA2,IGF1,HECTD2,ADAM11,NF1,NRCAM,NTRK2,ABCB1,PPARA,RELN,RBBP8,ROBO1,RXRA,HES6,TNFRSF19,SMPD3,NLGN1,SMARCA4,UNC5B,STXBP1,NSFL1C,SYP,ENHO,TSC2,ITM2C" Drug 3895_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-03 1.00E+00 1.29E-02 1.45E-01 34 179 "ALCAM,PLA2G4C,PDE8B,ADGRB2,LDLRAD4,CALB1,CHRNA4,PDE4DIP,EGR3,DLC1,PDLIM5,ALDH1L1,PCDH17,IFI16,KCNN2,MARK1,P2RY1,MBOAT7,CEP41,ZSCAN32,RPS6KA2,SGK1,SH3GL3,ARHGEF40,SOX15,PEG10,ZC3H13,CDK19,ARC,TBCEL,PCDHA5,HIRA,LAT2,NT5M" Drug 6184_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-03 1.00E+00 1.29E-02 1.45E-01 34 179 "ADORA1,PDE8B,CHRNA4,CREM,SIPA1L1,PDE4DIP,SNPH,DGKG,SV2B,FAM13A,MBNL2,FGFR1,BAIAP2,CACFD1,FAM107A,PDE4B,PFKFB2,PLCL1,PMP22,MBOAT7,PRKACB,CEP41,KLK6,PTPRN2,MARCH1,SCN2B,HSPA4L,FRMPD1,CDK19,ATP10B,JMJD6,OBSL1,ZBTB38,SLC17A7" Drug CID000443225 AC1L9E9N Stitch 1.80E-03 1.00E+00 1.29E-02 1.46E-01 6 13 "WASF1,CS,F5,STON1,TRERF1,CYB561A3" Drug CID003080722 3-aminopyridine adenine dinucleotide Stitch 1.80E-03 1.00E+00 1.29E-02 1.46E-01 6 13 "CD38,GPD1,GPD2,NBL1,ADHFE1,CYB561A3" Drug DB00151 L-Cysteine Drug Bank 1.80E-03 1.00E+00 1.29E-02 1.46E-01 6 13 "CARS,NFS1,CBS,CDO1,CTH,SLC19A3" Drug 3902_DN Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.83E-03 1.00E+00 1.32E-02 1.48E-01 35 186 "APBB2,GAS7,APLP1,CDK10,CDK13,AKAP12,SIPA1L1,PDE4DIP,DZIP3,GREB1,ZNF804A,LYPD1,DLC1,SCARA3,OGA,GHR,RUNDC3A,STON1,GPR37,ITPKB,JAK2,LMO2,MEIS2,MMP17,PDE4A,PLCD1,PPP5C,PKIA,PRKAR1B,LIMCH1,NXT2,TACC1,MCF2L,SLC44A1,ITM2C" Drug 6996_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-03 1.00E+00 1.32E-02 1.48E-01 35 186 "ABHD6,NME5,ARHGEF1,CBFA2T2,CRY2,PDE4DIP,CTH,SPOCK3,MED12,OPTN,EGR3,ANKMY1,RRAGB,ARMCX1,FHL1,SRCAP,RAB30,MAP4,MAPT,PLCD1,PRKAR1B,RIPOR1,RPS6KA2,EMID1,SUPT20H,SYBU,EPN2,KDM4B,SPTAN1,ANKRD12,MCF2L,TRIM2,PCDHA6,TK2,REEP1" Drug 2426_DN Progesterone [57-83-0]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.83E-03 1.00E+00 1.32E-02 1.48E-01 35 186 "ADRB2,CDC42BPA,PPFIA4,APOC1,SCAPER,CLGN,ARHGEF10,HDAC9,DTNA,FAM13A,ING4,ENO2,RASGRP2,GAA,MAN1B1,NCKAP1L,LSS,SLC11A2,PFKFB3,PLCB2,PILRA,CNNM2,SBF1,GALNT10,FAM102A,SLC2A5,FAM214B,SLC6A8,KDM4B,KDM3A,SPP1,PLCB1,TNS1,GDPD5,KAT6A" Drug CID000003816 NSC759587 Stitch 1.85E-03 1.00E+00 1.33E-02 1.50E-01 71 444 "ACHE,ADORA1,ADORA2A,AMH,GAS7,ATP2B2,BCS1L,CA4,CACNA2D1,CALB1,CALB2,CCK,SCARB1,CPNE6,CNR1,PICK1,OPTN,EIF4G2,ENO2,GPHN,NCALD,NRN1,PTK2B,AGAP2,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GGT7,GGT5,GLUL,GPR37,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GSTM5,GSTT2,ITPKA,KCND2,PACRG,MAP2,KITLG,MSR1,NPY,SERPINI1,GPSM2,PRKCB,MAPK10,ENOX1,GSTCD,FBXW7,S100B,SLC6A11,SNAP25,SPTAN1,SST,SYN2,SYP,SYT1,TACR1,MLST8,HEY1,SGK3,SLC30A3,SLC17A7,NETO2" Drug 7427_DN Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "APC,PPFIA3,CDC14B,BMP7,CBFA2T2,UBE2L6,ABCG1,DCAF8,SGSM2,SUGP2,APH1A,TNK2,EPB41L2,VPS26C,ANKFY1,ATP2C1,GHR,MUM1,IPO5,MAP4,NF1,NFYA,SLC25A23,PMP22,POLG,CLIP1,SMARCA4,SMARCC2,ZHX3,SPART,CEP68,PHLDB1,SIN3B,TP53BP1,HIRA,ST7" Drug 7004_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ADRA1D,LTBP4,ALDH7A1,SCAPER,RUNX1T1,ENTPD4,DOCK4,TMCC2,DNM1,ENO2,MTSS1L,VPS26C,FER,FHL1,SEMA4D,RUNDC3A,ELOVL5,HNMT,TJAP1,KCNF1,GIT1,NF1,NPY,GPR85,PRKAR1B,GTDC1,ROBO1,ZNF821,FBXO11,FAM214B,SNCA,PHLDB1,AP4E1,EMSY,GDPD5,SEMA3B" Drug 4450_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "APBB2,ADGRB2,SCARB1,ASIC3,NRXN3,RAB26,CNTN1,AKAP7,HAPLN1,SPOCK3,HIPK3,NCALD,ZNF589,IQCG,TRAF3IP2,KCNMB4,STON1,HAS2,ICA1,SCIN,ITPKA,ZNF862,PFKFB4,WDR25,RIPOR1,ZDHHC14,PEX26,ARHGEF40,BTBD7,KDM4B,DDN,CEP68,KIAA1107,TIAM1,TNS1,RPRM" Drug 6760_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "AP2A2,APAF1,BCAS1,NRP2,IL33,SCARB1,TAOK2,ABCG2,RGS6,SEC14L5,MFAP3L,DUSP9,ING4,F5,FGF1,CNTRL,GRM8,ELOVL5,SHISAL1,KIT,ADAM11,MSI1,ADAM22,MX1,PDE4B,GPR85,SLC25A23,PTPRH,ZFP30,HECW1,IQSEC2,DNAH7,R3HDM1,SLC30A4,EMSY,EPM2A" Drug 982_UP (-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ASIC1,ABHD6,NDRG2,ARNTL,BCL7A,CFLAR,B4GALT6,RAB28,RAB26,SIPA1L1,DZIP3,PHF14,CTH,DBT,SGSM2,ACOT8,ANKMY1,TDRKH,GPR37,RNFT2,JAK2,MAPT,MPP2,SLC11A2,PALM,PMP22,PRKAR1B,RGS3,TCP11L1,ASAP3,SPTAN1,LHPP,ELOVL4,REEP1,MAP3K12,SMIM8" Drug 3057_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "NUMB,KIF1A,BACH1,CLGN,TAOK2,EPS15L1,STOML1,MBNL2,COQ7,ERBB2,DLC1,SEPT9,INPP5K,ADAM28,LILRA2,MAP4,MID1,MYO6,NNAT,P2RY1,PDE4A,PFKFB2,RETREG1,SLC25A23,WDR25,SH3BGR,FAM102A,CPEB3,PEX26,SPTAN1,SPART,SYN2,TBL1X,TRPS1,CLIP2,PHTF2" Drug 2825_DN Probenecid [57-66-9]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ASPHD1,AMPD3,APOC1,CDK10,CFAP410,SCARB1,HOMER3,ABCG1,GREB1,PPP6R2,KIAA0586,RASGRP1,EGR3,ING4,GLYR1,RAB30,IL6ST,JAK2,MAP4,MPP2,NPR2,RETREG1,SMOX,PRKAB2,MAPK7,NKAIN1,RET,SBF1,ATXN2,SGK1,SPTAN1,ARC,EXOC7,PLPPR2,HPS4,SEMA3B" Drug 3166_UP Clotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "NME5,ABCD2,ATP1A3,ADAM23,SCAPER,MTMR3,CNN3,CRYBB1,AATK,RASSF2,C2CD2L,SLC12A6,DTNA,DUSP9,C3orf18,DLC1,AGAP2,SRCAP,RUNDC3A,JAK2,KCNJ5,MITF,MSR1,GPR85,RGS12,RPS6KA2,SH3BP2,SLC2A5,SLC6A8,ARHGAP26,TRIM2,CDK20,UGT8,WIPF1,XRCC4,SEMA3B" Drug 3181_DN Ethacrynic acid [58-54-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ADCY6,DOC2A,PPFIA3,CAMK2G,TAOK2,FGFR1,FGFR3,BAIAP2,CGREF1,TXNL4A,POLL,CNTRL,GRB10,PADI2,ITPKB,KCNF1,MAP4,LRP12,MBOAT7,WDR25,CEP97,RGS3,EMID1,AMBRA1,KIF13A,SOX3,STX1A,TACC1,IQCE,ZNF34,SLC44A1,TIAM1,NPL,HIRA,VAV1,EMSY" Drug 4712_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ADORA1,AMPD3,CDC42BPA,PLA2G4C,ARHGEF1,DGKI,CDH2,WHRN,CRMP1,ARHGEF10,RIPOR2,RCAN1,FGFR1,GAD1,ALDH1L1,SRCAP,GLYR1,PCLO,SYNPO,KCNF1,ADAM11,NF1,CNOT4,SERPINI1,PTX3,C1orf54,TCP11L1,SLA,PHLDB1,VPS13A,PCDHA6,TNS1,AMACR,NT5M,SEMA3B,FAM13C" Drug 3209_DN Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "CDC14B,SCARB1,QKI,HOMER3,WHRN,PDE4DIP,CTH,DAPK3,DBT,SLC12A6,EDNRA,FEM1B,BAIAP2,ERAP1,SEPT9,TXNL4A,AGFG1,DHX35,JAK2,MBNL1,KITLG,PRKAB2,MAPK7,EPN2,KDM4C,IQSEC2,TROVE2,NXT2,ARHGEF9,EXOC7,PCDHA6,TMPO,CABIN1,VGF,REEP1,MPPE1" Drug 6512_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "LTBP4,BEGAIN,AMPH,APBB2,APOC1,ATP2B2,N4BP2L1,CAMK2B,CAMK2G,HIP1R,CBARP,WHRN,NCOR2,IPCEF1,GREB1,CYBB,RUSC2,DTNA,SCARA3,AGAP2,SIGLEC8,PTPRT,RASSF8,KIF5A,MAN2A2,MATK,MBD1,NF1,RASGRF1,FBXW7,PPP4R3A,PLCB1,EXOC7,SLC44A1,TK2,HIRA" Drug 4410_DN Captopril [62571-86-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "NDRG2,AK2,BIN1,CFLAR,MTMR3,LDLRAD4,ARHGEF2,TAOK2,LHX2,SPOCK2,EGFR,TRAF3IP2,TMEM8B,SEPT9,RUNDC3A,GNAL,TDRKH,STON1,IL6R,IL6ST,KCNN2,KCNQ3,SERPINI1,RETREG1,PTN,EMID1,KCNIP1,EPN2,SNCA,PLCB1,ARC,TBL1X,PCDHGA10,R3HDM1,HIRA,UPF3A" Drug 2675_DN prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "N4BP2L1,MPDZ,LDLRAD4,IQCK,ARMC8,RCHY1,SLITRK5,TSPAN5,ELN,RASGRP2,MTSS1L,ZNF44,ERAP1,SEPT9,MGAT3,PDE4B,RIPOR1,KHDRBS2,RGS3,PLPPR3,SCN2B,FRMPD1,FAM214B,BTBD7,SMARCA4,ARHGAP26,DDN,CEP68,PDLIM2,KIAA0930,SYNE1,THRA,UBTF,LMF1,CLIP2,NLRP3" Drug 3850_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ADORA1,NME5,BACH1,MTMR3,CAMK2B,CLGN,CNTNAP2,FAM169A,DAPK3,SPOCK2,ING4,ERCC2,SPEG,CAMKK2,FUT9,NEU3,SPIN1,GPER1,PCLO,GSN,KHK,LSS,KITLG,MARCH1,RGS12,RPS6KA2,PPP4R3A,OGDHL,FAIM2,RBM34,TSNAXIP1,ZBTB43,SZT2,PIK3R5,KCNAB1,KAT6A" Drug 2505_DN Ricinine [524-40-3]; Down 200; 24.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "ADORA2A,ANK2,CDK13,SLC4A4,SYNJ2,LDLRAD4,CAMK2G,CAPN3,CCNT1,SIPA1L1,SPOCK3,TOM1,FAM13A,MTSS1L,PDLIM5,SRCAP,LILRA2,MAP4,MGAT3,MIA2,NF1,NNAT,PLTP,LRRN3,RNASEL,PLPPR3,FAM102A,MYH15,KDM4C,RBM26,DIP2A,PARD3,CABIN1,FLRT2,ZNF32,NT5M" Drug 3183_UP "Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.87E-03 1.00E+00 1.33E-02 1.50E-01 36 193 "SYN3,ADGRF5,APLP1,PRX,PPP4R4,ARHGDIG,AZGP1,NRP2,CAMK2B,WHRN,CNTNAP2,C2CD2L,SV2B,HPCAL4,AGAP2,KHDRBS3,DISC1,INPP5K,GLI2,GNAL,MAP4,MAPT,MARK1,MEF2C,AFDN,ADAM22,PDE4A,PDE4B,PKNOX2,SYT5,TCF4,TEK,TNS1,KCNK12,ZNF45,NT5M" Drug CID000005466 AC1Q5UBL Stitch 1.88E-03 1.00E+00 1.34E-02 1.51E-01 29 146 "ACHE,ADCY8,ADORA2A,ADRA1B,ADRB2,ALDH7A1,CACNA1B,CACNA2D1,KRIT1,CHN1,BOC,NR1D2,ADGRV1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GRIA2,GRIK4,GRIK5,GRM2,GRM8,MEST,MGAT3,OPRL1,PTCH1,SLC6A11,SLC17A7" Drug 2446_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.88E-03 1.00E+00 1.35E-02 1.52E-01 32 166 "BIN1,FAM131A,DNAH17,CFLAR,CACNA1I,HIP1R,CD86,CD38,CHN2,AKAP6,COL9A3,CREM,AATK,SIPA1L1,PPP1R16B,DOCK4,PRKAG2,GALC,NINJ2,TREM2,PDE4B,PDE4D,PILRA,PID1,ACSS3,ZMAT4,MAP6D1,SGK1,FAM214B,PHLDB1,TRPS1,FLRT2" Drug 4725_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "BIN1,APBA2,MARK4,SLC2A11,LDLRAD4,CBFA2T2,AKAP7,CSF1R,ARHGEF10,CSNK1E,BRINP1,SPOCK3,DMPK,CDON,AASS,MRNIP,HSD17B14,FYB1,GAD1,SEPT9,SRCAP,GNG4,CACFD1,MGAT3,ADAM22,NPTX1,SLC11A2,PEX26,STX1A,PLCB1,TRIM2,THRA,TRIO,VIPR2,SPHK2,DNALI1,KAT6A" Drug 6005_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ANK2,RGS20,ZSCAN18,NRP2,BAIAP3,USP2,DGKB,SPOCK2,JAKMIP2,HIPK3,PLXNC1,RASGRP2,INPP5K,SRCAP,LYVE1,GPER1,MAP2,MID1,AFDN,MSI1,NTRK3,MINDY2,PRODH,ELOVL2,TMEM231,KCTD17,KLHDC8A,SH3BP2,ASAP3,FBXO11,SLC11A1,LIMCH1,FAIM2,KDM4C,GPR161,ZNF74,ST7" Drug 6359_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "OGT,APC,ATP2B2,KIF1A,BMP7,B4GALT6,LHX2,TPP1,SH2B1,NCOR2,VCAN,E2F5,PLXNC1,TENM1,OLFM1,SCARA3,FYB1,SIGLEC8,PADI2,ZNF862,NF1,SETD4,KHDRBS2,RIC8B,ATXN7,FRMPD1,CNKSR2,ELMO2,KDM4C,SS18,ADGRL3,R3HDM1,TRIO,VGF,XRCC4,REEP1,PHTF2" Drug 2648_UP Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADORA1,AP2A2,TRMT9B,AMPD3,FAM131A,CDC14B,SLC2A11,ADGRB1,CAMK2B,ARHGAP33,CHN2,SLIT2,TPP1,LRIG1,DTNB,PIPOX,ANKMY1,DLC1,FGFR1,SEMA4D,PRELID3A,IL6ST,MAN2A2,MBD1,MIA2,MBOAT7,TCP11L1,KIF13A,IZUMO4,SPTAN1,IQSEC2,PLCB1,EXOC7,PARD3,ZKSCAN5,FAM13C,AP3B2" Drug 3640_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "AP2A2,APOC1,ADAM15,HAP1,CAMK2B,SLC16A4,AKAP7,AKAP5,CRY2,GREB1,MFAP3L,CDON,ING4,FGFR1,FYN,GAD1,ALDH1L1,GPER1,GSN,RNFT2,CLDN11,PLCD1,MBOAT7,RIPOR1,ZSCAN2,KCTD17,GSTCD,ANKRD6,SLC2A5,DOK5,SPTB,TROVE2,PHLDB1,KIAA1107,TBCEL,ZKSCAN5,FLRT2" Drug 2157_DN Austricine [10180-88-8]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "NDRG2,PPP4R4,ATP2A2,MYRF,CACNA1A,FOXN3,PLAA,CNTN1,SH2B1,PDE4DIP,SGSM2,RCAN1,ELN,RASGRP2,CDKL3,F5,AFF2,KHDRBS3,SRCAP,USP19,KCNMB4,LILRA2,GIT1,MYT1,POU6F1,PPARA,ZSCAN32,ANKRD6,EPN2,BTBD7,DOK5,JMJD6,PLCB1,DNMBP,PARD3,ST7,PHTF2" Drug 5927_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "TRMT9B,BIN1,SEMA7A,APBB2,PPFIA3,CACNA1I,BAIAP3,SCARB1,PLEKHB1,TAOK2,WHRN,BAG4,AKAP12,CSF1R,DAPK3,MFAP3L,DMPK,ERCC2,ACSL4,BAIAP2,IQCG,PDLIM5,COPS8,GNG4,HNMT,KCNH2,LRP12,LIMS2,ELMO2,ZHX3,SS18,NSFL1C,TBCEL,TRIM2,SPHK2,SH3GLB2,GDPD5" Drug 1_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ABR,ADORA2A,BIN1,ANK2,PPFIA3,SYNJ2,ARHGEF7,CHGB,CHN2,VAX2,TMEM184B,ARHGEF6,ARHGAP32,DCAF8,INTS1,DMPK,DTNA,DUSP9,FEM1B,SUGP2,PRKAG2,TRMO,RUNDC3A,CNTRL,ATXN2L,ADAM22,NTRK3,CEP41,PRPSAP2,VPS13C,ATXN2,SEC14L1,SH3BP2,NMNAT2,SSBP2,PLPPR2,WRN" Drug 7315_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "STX16,ST3GAL5,IL33,RCBTB2,PLAA,QKI,ENTPD4,PDE4DIP,SLITRK5,GIT2,LYPD1,ACOT8,IRAK4,COQ7,FGFR1,SCARA3,CGREF1,GCNT2,TXNL4A,GLYR1,GPER1,CNTRL,SYNPO,MAP4,TAGLN3,NF1,NPR2,RAD51D,SH3TC2,RPS6KA2,ZBTB43,ITPRID2,ELOVL4,RUNDC3B,ZKSCAN5,ZNF711,ZNF45" Drug 5048_DN Etofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "NME5,TRMT9B,KCNAB2,APC,APLP1,SCAPER,GYG2,AKAP7,CRY2,CNTNAP2,CHRDL1,TOM1,EDIL3,EDNRA,FAM13A,MRNIP,SEMA4D,TMEM8B,SRCAP,CNTRL,ZNF862,SERPINI1,PIK3R1,SLC25A23,KLK6,CNNM2,PTN,KIRREL1,RXRA,MAPK12,SCN8A,FUZ,ST6GAL1,DZIP1,KLC2,ZNF32,EVI5" Drug 3503_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADD2,SEMA6A,LTBP4,APBA2,APBB2,ATP1A3,ADGRB1,ARHGEF1,ARHGAP33,CACNA2D2,CHGB,AATK,PDE4DIP,SNPH,SPOCK2,ARMCX2,TENM1,CORO2B,AGAP2,ZNF44,GFER,LPAR4,ICA1,KPNA5,ADAM22,MYT1,PDE4D,NLE1,PPP2R2B,MAPK7,RPS6KA2,SLC11A1,ZNF423,TROVE2,TNS2,PCDHA5,PDIA2" Drug 1079_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "CFLAR,BMP7,MTMR3,MTMR2,C5,HIP1R,UBE2L6,SRSF11,LHX2,C2CD2,SOCS5,PDE4DIP,GIT2,DBT,MFAP3L,FBXL5,RCAN1,ENO2,ERBB2,BAIAP2,PDLIM5,HTATSF1,RAB40B,PADI2,MAP4,PLEC,ZSCAN32,ANKRD6,NUBPL,ELMO2,PDZRN3,ZSWIM8,DIP2A,JMJD6,NSD1,PARD3,RPRM" Drug 2395_UP Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "MTUS1,SRPX,CDC42BPA,APBB2,PRX,PDE8B,C5,RUNX1T1,CDH2,RAB33A,ABI3BP,CREM,SH2B1,HAPLN1,CELSR3,MTSS1L,FER,AGAP2,ICA1,NELL2,NFIX,MAPK10,RGS3,KCNIP1,ZNF821,LIMS2,FAM214B,DOP1A,KDM4C,UNC5B,RBM26,TNS1,TPM1,TRPS1,VGF,SPHK2,REEP1" Drug 1685_UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "AP2A2,KCNAB2,APC,CDC14B,ARHGDIG,BMP7,HIP1R,KYAT1,CCNT1,FOXN3,B4GALT6,RAB28,BAG4,GPRASP1,FCF1,MBNL2,ERCC2,NCALD,BAIAP2,GNG4,INPP5B,MAP4,NFYA,PCDH9,FSD1,RAD51D,SEC14L1,TRA2B,FBXO11,FNDC3A,BTBD7,HECW1,KDM4C,CEP68,EXOC7,TRIM2,GDPD5" Drug 5465_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ARHGDIG,MARK4,PTCH2,ARHGEF7,MTMR2,HAP1,FOXN3,MFAP3L,MBNL2,RASGRP2,EPHB1,STX2,ACSL4,PDLIM5,ERAP1,PADI2,VSIG4,DHX35,IL6ST,KHK,ZNF862,SLC11A2,PDE1C,GPR85,PLTP,CCDC40,SH3GL3,FBXO11,ELMO2,CXXC4,KDM4B,CLSTN2,ARHGEF9,DOCK9,RUNDC3B,ZKSCAN5,EVI5" Drug 4475_DN Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "NME5,SEMA4G,CASK,ARNTL,CDK13,MARCH3,SYNJ2,IL33,KRIT1,CBFA2T2,RCBTB2,SOCS6,CHN2,ABI3BP,CNTNAP2,DCAF8,RCAN1,EIF5,MRNIP,STX2,ETV1,CINP,B4GALNT1,GPER1,HNMT,INPP5B,MMP16,PCDH9,PFKFB2,KDM4D,DOP1A,SPATA7,NXT2,DICER1,BHLHB9,TMPO,PHTF2" Drug 3765_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ASIC1,ALK,ADGRB2,BMP7,ABCG2,CRMP1,CNTNAP2,GPRASP1,CDKL3,FGFR1,SYT17,CACFD1,IL6ST,IL12A,NF1,NFYA,P2RY1,GRAMD1C,PRPH,WDR25,ZSCAN32,ACSS3,TCP11L1,SBF1,ASAP3,FNDC3A,ZNF667,SNCA,RBM34,LHPP,SAMSN1,THSD1,SZT2,DNAH7,GPR161,WNT7A,SPHK2" Drug 5750_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "RALGAPA1,AP2A2,C1QTNF1,CDC42BPA,PPFIA3,SLC4A4,B4GALT6,RAB28,ENTPD4,NCOR1,CSF1,DZIP3,FAM49B,TDRKH,GPER1,IL12A,INPP5B,KCNH2,MAPT,MX1,ZNF862,PTPRN2,KCTD17,LIMS2,KBTBD4,DOK5,PHLDB1,STX1A,COBL,DNAH7,CABIN1,HIRA,VGF,WIPF1,NDRG4,MAP3K12,KCNAB1" Drug 3340_DN Simvastatin [79902-63-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADORA2A,APBB2,PLA2G4C,MARK4,CA4,SOCS6,B4GALT6,CSF1,ARMCX2,ING4,STX2,FER,FGFR1,IQCG,SEMA4D,CNTRL,SPACA9,KCNH2,KCNJ5,ADAM22,SETD4,PTN,CEP97,SH3BP2,ANKRD6,ABLIM3,ZSWIM8,CDK19,ELOVL4,PCDHA6,TMEM121,TK2,VLDLR,HPS4,PCBP4,ST7,SMIM8" Drug 2725_DN Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ASIC1,ADRA1D,AMPD3,APC,PPP4R4,ATP2A2,CACNA1A,EPS15L1,HOMER3,IQCK,NRG2,PPP1R16B,USP6NL,RCAN1,IGSF6,IQCG,SEPT9,GPR75,POLL,ATXN2L,IFI16,KPNA5,SMAD1,NNAT,TMEM104,ZNF821,ANKRD6,SLC11A1,TMCC1,TROVE2,EXOC7,ADGRL3,KIAA1107,TK2,LMF1,MAP3K12,TIGD6" Drug 6503_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADD1,DOC2A,EPB41L5,APOC1,PPFIA3,CDK10,ATP2A2,MTMR2,AP4M1,CRLF1,B4GALT6,PLAA,DAPK3,DBT,DNM1,CELSR3,ING4,MRNIP,EPB41L2,STX2,BAIAP2,ERAP1,GNG4,MAPT,ZNF862,OCRL,PLXNB1,PPP2R2B,EMID1,LIMCH1,CLASP2,TACC1,HIRA,XRCC4,REEP1,EMSY,RNF170" Drug 7483_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "APC,APOC1,KSR1,SYNJ2,CFAP410,ARHGAP33,CLGN,CRLF1,CSF1,CDON,EDNRA,CNNM1,CELSR3,EGFR,MBNL2,ING4,BAIAP2,PDLIM5,SYT17,TXNL4A,IPO5,MATK,MIA2,AFF1,ZNF862,PDE4A,MBOAT7,RIPOR1,RNASEL,SEC14L1,FAM214B,ZNF423,ZC3H13,PHLDB1,STX1A,MCF2L,UBE3B" Drug 378_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "RALGAPA1,MTUS1,EPB41L5,PPFIA3,AQP6,ADAM23,SYNJ2,SEPT7,STOML1,PICK1,RIMS2,FAM13A,ING4,OLFM1,FYB1,SRCAP,ADAMTS13,SOX21,IRAK3,MAN1B1,NTRK3,CLDN11,P2RX7,SMOX,MBOAT7,PPP5C,ZC3H14,FUZ,LIMS2,ZHX3,ZSWIM8,ZC3H13,ST5,PLCB1,TCF4,HIF3A,TSN" Drug 1724_UP Imipenem [74431-23-5]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "NDRG2,BRAP,ARNTL,NCOA1,TMEM184B,AKAP7,SEC31B,CRY2,CSF1,CSF1R,RUBCN,DCTN1,C2CD2L,FLT1,MAN1B1,ACOT7,KCNN1,MAN2A2,RETREG1,PLCB2,CNNM2,PTX3,RNASEL,TCP11L1,AMBRA1,BTBD3,ARHGEF40,CCDC88A,DOK5,ERC1,IQSEC2,SZT2,NACC2,PARD3,FLRT2,NPDC1,XRCC4" Drug 6617_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADRA1D,NME5,BIN1,CDC42BPA,DNAH17,KYAT1,CBFA2T2,WHRN,CPS1,EXOG,MBNL2,MRNIP,DENND2A,USP19,STON1,GPER1,GPR37,IL6ST,SMAD1,MAP4,MAPT,MIA2,ADAM22,NEK1,PID1,FAM184A,SBF1,ZNF821,ANKRD6,ZNF667,SS18,ASTN2,TIAM1,NR2C2,SSBP2,EMSY,NAV3" Drug 1704_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "APBB2,BCAS1,PPFIA3,PRX,MARCH3,SCAPER,LDLRAD4,ARHGEF1,SOCS6,PLEKHB1,TAOK2,PICK1,NRG2,ZNF589,FECH,FHL1,SEMA4D,TMEM8B,RUNDC3A,TXNL4A,POLL,DIDO1,CDK18,PFKFB2,GDPD2,PTCH1,ELOVL2,SUPT20H,ASAP3,SMARCD3,KIF13A,TRIM2,ZKSCAN5,VIPR2,WIPF1,SPHK2,EMSY" Drug 6095_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "C1QTNF1,BEGAIN,BIN1,PLA2G4C,SEPT7,LY86,ABCG1,KLHL3,SPOCK3,FAM13A,AASS,LPAR4,SOX21,ADAMTS6,IRAK3,KCNH2,NCF2,NEK1,PCBP3,NTRK2,CLDN11,PNMA3,RELN,SAMD9,ZSCAN32,PTPRB,CCDC40,KCTD17,TCP11L1,SLC2A5,SNCA,SPTB,SPART,TK2,SPHK2,ITM2C,PHTF2" Drug 5634_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "APAF1,APOC1,PRX,NRP2,KSR1,FUBP1,ARHGEF1,RAB33A,CNTFR,WHRN,CLIP3,AATK,CSF1,EDNRB,PHF20L1,DISC1,PCLO,GSTM5,SOX21,ICA1,ZNF862,NF1,NECAB2,MAPK7,CNTLN,CCDC40,TCP11L1,STUM,HKDC1,PKNOX2,KDM4B,SPTB,CUX2,FLRT2,SPHK2,KCNAB1,EPM2A" Drug 7544_DN CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADORA1,EPB41L5,ARMCX2,EGFR,CDKL3,EZH1,FAM49B,POLL,CNTRL,MAP4K5,IRAK3,RASSF8,NF1,NFYA,CCSER2,PLCD1,SNRK,TMEM231,RAD51D,GTDC1,RGS12,SH3BP2,SLC22A4,LIMCH1,RBM34,CLSTN2,SS18,TTBK2,PLCB1,THRA,ZKSCAN5,VGF,VLDLR,LMF1,SPHK2,EPM2A,TIGD6" Drug 1281_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ABHD6,NDRG2,MTUS1,TRMT9B,CDC42BPA,GAS7,CDK10,CFAP410,CAMK2G,CREM,DCAF8,SPOCK2,SGSM2,SEZ6L2,CNNM1,PLXNC1,CGREF1,SRCAP,SLC2A6,MAP4,MEF2C,GIT1,PDE4D,CNTLN,RFX2,RASA3,MYH15,KDM4B,DOK5,IZUMO4,KDM4C,DNMBP,SZT2,THRA,PIK3R5,SMUG1,PLPPR2" Drug 6181_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "OGT,BCAS1,CDK10,SLC2A11,MPDZ,BMP7,SLC16A4,ARHGEF10,SEZ6L2,MRNIP,C3orf18,FGFR3,FHL1,ADAM28,PCLO,GRIK5,GUCY1B1,KCNJ5,KCNN1,MSR1,TAGLN3,SAMD14,NF1,PDE4D,CNNM2,MARCH1,RPS20,ZNF821,EPN2,KDM4B,TSNAXIP1,PEG10,LHPP,ADGRL3,HIF3A,TRIO,TRIM9" Drug 4140_UP Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ASPHD1,AP2A2,SPARCL1,ATP2B2,N4BP2L1,ADAM15,BCL7A,SYNJ2,CACNA1I,RUNX1T1,HOMER3,WHRN,CRY2,CST3,RIMS2,DAPK3,SPOCK2,DMPK,OLFM1,GNAL,GPER1,ACOT7,ICA1,C2orf72,ITGA7,KCNN1,OGG1,GDPD2,TRIM68,SH3BP2,SLC2A5,SLC11A1,LIMCH1,DOP1A,KIAA1107,CRTC1,TPM2" Drug 5535_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.89E-03 1.00E+00 1.35E-02 1.52E-01 37 200 "ADRA1D,AGT,NME5,SPARCL1,CDK10,PLA2G4C,CAMK2B,CBFA2T2,CLGN,RAB28,WHRN,CNTNAP2,SPOCK2,DTNA,SCML2,CORO2B,ZNF589,FHL1,TMEM8B,GPER1,IPO5,MAN2A2,MX1,NEFM,NF1,NNAT,NPTX2,NLE1,MTRF1L,STRN3,SAMD9,BTBD7,RBM26,HEY1,TNS1,SMUG1,ZKSCAN5" Drug CID000001345 PK11195 Stitch 1.89E-03 1.00E+00 1.35E-02 1.52E-01 12 42 "ALDH7A1,RIPK1,CACNA2D1,CBR1,DBI,ZMYND10,GABRG1,GABRG2,PRPH,SARS,ZEB1,HPS4" Drug CID000004355 AC1L1HZ7 Stitch 1.89E-03 1.00E+00 1.35E-02 1.52E-01 12 42 "APLP1,CA4,CAST,ZMYND10,MAPT,NFE2L2,PKM,MAPK10,SST,SYN1,SYN2,UBC" Drug CID000002753 cilostamide Stitch 1.89E-03 1.00E+00 1.35E-02 1.52E-01 25 120 "ADCY5,ADCY6,ADCY8,ADRB2,PDE8B,ALDH7A1,CALM1,CCK,LRBA,CNTFR,SH2B1,VCAN,TUBB3,CIT,IGF1,NPY,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,PBRM1,FNDC3A" Drug ctd:C043680 ptaquiloside CTD 1.90E-03 1.00E+00 1.35E-02 1.52E-01 27 133 "PCDH10,DST,CACNB4,COL9A1,CNTNAP2,EBF1,EDNRA,EGFR,ADGRV1,SESN1,GGT5,IGF1,LAMA2,MEIS1,MEIS2,MITF,NRCAM,NTRK2,PPARA,RET,FERMT1,ABLIM3,SOX11,SPP1,SYN2,SYT1,PCDHB7" Drug CID005315496 AC1NST48 Stitch 1.92E-03 1.00E+00 1.37E-02 1.54E-01 91 595 "AP2A1,OSBPL1A,ABCD2,APLP1,DYNLL1,STX16,KIF1A,ADAM15,GPC2,ENTPD2,ENTPD6,AP4M1,LRBA,CDR1,COPB2,CHGB,B4GALT6,CLTC,CNTN1,AKAP5,GAL3ST1,HAPLN1,VCAN,SPOCK2,DCTN1,SPOCK3,DNM1,RCAN1,DNM1L,EGFR,GOLGA7,STX2,CD320,TUBB3,FCGRT,FGF1,AGAP2,AGAP3,DCTN2,FOLR2,NBEA,ERGIC3,AP4B1,B4GALNT1,NEU3,GCNT2,ARFIP1,AP4S1,GABARAPL2,HMGCR,SMAP1,ITPKB,KCND2,KCNH2,KIF5A,LAMP2,OCRL,PCSK1,PCSK5,PDE1C,GPR85,ABCB1,PIK3C2A,SNX10,PLTP,PRKACB,MAPK3,PID1,ALG9,CLIP1,AP1AR,SMPD3,ST6GAL1,SYBU,ARFGAP1,SNAP25,BDP1,SPTB,STX1A,SULF2,NSFL1C,EXOC7,AP4E1,ACTR6,SGK3,UBC,GORASP1,SLC30A3,PLD4,AP3B2,ST8SIA2" Drug 1065_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.98E-03 1.00E+00 1.40E-02 1.58E-01 34 180 "OSBPL1A,OGT,APBB2,CDK10,CBFA2T2,TPP1,LETMD1,ARHGAP32,GIT2,DMTF1,ACOT8,MBNL2,ING4,CDKL3,KAT8,OGA,INPP5K,BRD8,GLYR1,STON1,MXI1,ZNF862,PPM1B,ZSCAN32,PCMTD2,FNDC3A,KDM4B,KDM3A,SPTAN1,CDK19,CEP68,TST,UBE2H,MARCH8" Drug 4541_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.98E-03 1.00E+00 1.40E-02 1.58E-01 34 180 "MAP4K3,APC,ARHGEF7,SOCS6,NECTIN3,PUM1,FAM13A,SEC24B,DIDO1,KIF2A,MARK3,MEF2C,NFE2L2,NFYA,CNOT4,PFKFB3,STRN3,PPM1B,SETD5,SCAF8,CHD9,SYBU,WDR47,JMJD6,ZC3H4,ANKRD12,MTCL1,ZEB1,PUM2,KAT6B,ZNF45,ZNF189,KAT6A,JMJD1C" Drug 2410_UP Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.98E-03 1.00E+00 1.40E-02 1.58E-01 34 180 "MTUS1,AGT,APAF1,ARRB2,C5,ENTPD4,CSNK1E,PDE4DIP,PPP1R16B,HIPK3,MBNL2,CDKL3,PDLIM5,CAMKK2,GNAO1,HMGCR,ICA1,LSS,MT1M,MYCN,P2RX7,ENPP2,CCSER2,PLCL1,CNNM2,ZNF821,GALNT10,SGK1,SPP1,SS18,SYNE1,CRTC1,SSBP2,FLRT2" Drug CID000004284 DETA Stitch 1.99E-03 1.00E+00 1.41E-02 1.59E-01 24 114 "KCNH8,ACHE,SEMA6A,SEMA7A,SEMA4G,BCHE,NRP2,SLIT2,DMPK,PTK2B,EVL,SEMA4D,GAD1,KAT7,NELL2,NPTX1,ABCB1,MAPK9,PTK2,ROBO1,ROBO2,SEMA6D,SEMA3B,RTN4" Drug ctd:C506614 PD 0325901 CTD 1.99E-03 1.00E+00 1.41E-02 1.59E-01 24 114 "FMNL2,NME5,SLIT2,AKAP12,DOCK4,HDAC9,ARHGAP24,ETV1,ST3GAL6,ADAMTS6,HAS2,KIT,NF1,NRCAM,MAPK3,RELN,PTX3,SPP1,STX1A,DNMBP,ZEB1,TLR4,UGT8,NAV3" Drug CID000107778 HU-211 Stitch 1.99E-03 1.00E+00 1.41E-02 1.59E-01 24 114 "ADCY5,CBR1,CBS,CNR1,EDIL3,TUBD1,TUBB3,TUBA8,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,PIK3C2A,PIK3R1,PPARA,MAPK9,PTK2,ACTR6,TUBB2A,TUBB1,TUBA1A" Drug CID000002703 chelerythrine Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 59 357 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,CACNA2D1,CALM1,CAMK2B,CCK,KRIT1,DGKI,LRBA,MYL6B,CTH,DGKB,DGKG,DBI,SLC12A6,EDN1,EDN3,EDNRA,EGFR,PTK2B,GRIN2C,GRIN2D,GRM2,GRM8,TNFAIP8L3,MYLK2,SCIN,OPRL1,OXTR,P2RX7,PIK3C2A,PIK3R1,PKM,MBOAT7,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,PSMA6,PTK2,MAPK12,SMPD3,SLC9A5,SLC12A4,STAU1,ACTR6,CABIN1,CDK20,PLD4" Drug CID006102718 1 aa Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "ADORA1,AMPH,CBS,SUMF2,DNM1,HIPK3,TUBB3,MX1" Drug CID000162797 HWA 153 Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "PDE8B,ALDH7A1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000065959 Iomazenil (123I Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "BRAP,CA4,GABRB3,GABRG1,GABRG2,ZEB1,SMUG1,RTN4" Drug CID000060860 metaiodobenzylguanidine Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "CBFA2T2,ENO2,MCHR1,MYCN,SST,SSTR1,SSTR2,SMUG1" Drug CID000445682 Fe-mo-s Cluster Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "CSF1R,GRIA2,GRIK5,GRM8,MITF,ENPP2,ARHGAP9,RASD2" Drug CID000001978 acebutolol Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "ADRB2,CACNA2D1,TBPL1,ERBB2,COPS8,ABCB1,PMP22,NETO1" Drug CID000127296 PP-IP(5 Stitch 2.01E-03 1.00E+00 1.43E-02 1.61E-01 8 22 "IP6K1,IP6K2,IP6K3,ITPKA,ITPKB,MAPK3,NUDT11,NUDT10" Drug 2671_DN retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.01E-03 1.00E+00 1.43E-02 1.61E-01 35 187 "ADRB2,TRMT9B,NUMB,C5,CACNA1A,CSNK1E,VCAN,DOCK4,DTNA,ELN,MTSS1L,FHL1,CAMKK2,FYN,ZNF44,SEPT9,COPS8,POLL,ACOT7,KIF2A,MAP4,TM6SF1,MGAT3,SLC11A2,PLEC,PTX3,ARHGAP26,DDN,ANKRD28,TBL1X,ZEB1,SSBP2,XRCC4,NAV3,TIGD6" Drug 1220_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.02E-03 1.00E+00 1.43E-02 1.61E-01 31 160 "ABHD6,ADRB2,ARNTL,ST3GAL5,ABCG1,PDE4DIP,CTH,C2CD2L,PLPPR4,RGS17,TAOK3,BAIAP2,FYN,GUCY1B1,BACH2,FAM69A,MAPT,MEF2C,MMP16,PCDH9,SERPINI1,RETREG1,PTCH1,RGS4,SH3GL3,KDM4B,ARHGAP26,ELOVL4,RGL1,SYT1,TACC1" Drug CID006442852 AC1O5Y0F Stitch 2.04E-03 1.00E+00 1.44E-02 1.62E-01 11 37 "TUBD1,TUBB3,TUBA8,MAP2,NEFM,NEFH,CLSTN2,SYN2,TUBB2A,TUBB1,TUBA1A" Drug 2295_DN Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ASPHD1,PPFIA3,ARHGEF1,TPP1,BAG4,FAM169A,DZIP3,GIT2,LYPD1,IRAK4,ING4,COQ7,F8,ACSL4,ZNF589,TRMO,GNG4,MBD1,MPP2,ZNF862,NFYA,SLC11A2,PPP5C,FERMT1,FBXO11,PPP4R3A,KBTBD4,BTBD7,PCDHA6,TMPO,BEX4,HIRA,CLDND1,EMSY,GDPD5,UBE3B" Drug 1606_UP Metergoline [17692-51-2]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "NDRG2,ARNTL,SYNJ2,RAB28,CRMP1,FBXL5,EGR3,EPB41L2,VPS26C,EZH1,SEMA4D,FLNC,TRMO,OGA,GFER,GRIK5,HMGCR,LSS,GIT1,SETD4,ENPP2,PLCB2,PLCD1,ZNF426,VPS13C,PTX3,ATXN2,SGK1,AMBRA1,MAPKBP1,IQSEC2,THSD1,STXBP1,MGRN1,REEP1,AAAS" Drug 7413_UP Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "LTBP4,APBB2,ST3GAL5,KYAT1,CCNT1,CRLF1,SULT4A1,NECTIN3,ENTPD4,HAPLN1,DCAF4,C2CD2L,TOM1,HIPK3,FEM1B,OPTN,MBNL2,PLXNC1,COQ7,FGFR1,BAIAP2,FYB1,LIG4,SMAD1,MAPT,NELL2,SLC11A2,SETD4,SEC14L1,FAM214B,ELMO2,MAPKBP1,ANKRD12,AP4E1,VLDLR,MAP3K12" Drug 1217_DN chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "AMT,CDC42BPA,MADD,CA12,CDC25B,SOCS6,NCOR1,OSBPL3,ARHGEF4,ARHGAP32,C2CD2L,TUBD1,ETV1,EZH1,FCGRT,ZNF589,GAD1,AHDC1,PRRC2B,MAN1B1,PCDH9,PDE4B,MBOAT7,PRPH,RIPOR1,RAD51D,ZDHHC14,SBF1,PEX26,SMARCC2,STX1A,CLASP1,HIRA,TRIM9,MAP3K12,PLSCR4" Drug 2799_UP Gramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ADORA1,LTBP4,LDLRAD4,CAMK2A,CAMK2B,CAMK2G,CBFA2T2,AKAP7,DUSP9,FAM198B,ERAP1,GFER,GRM8,IL6ST,KCNQ3,MAPT,MEF2C,MID1,PRKAR1B,KLHDC8A,RPS6KA2,SEMA6D,ARHGEF40,HECW1,TSPYL2,SPART,EXOC7,KIAA1107,TBCEL,TRIM2,GPR161,TK2,CABIN1,CA14,UCHL1,KAT6A" Drug 6893_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ASIC1,AP2A2,ARNTL,ADGRB2,WHRN,ABI3BP,CNTNAP2,FAM13A,ING4,ETV1,FHL1,CINP,DLL3,GPER1,GRIK5,ZNF862,CCSER2,RETREG1,PLEC,BCAS3,PTPRH,BEND5,ZNF821,SMARCD3,SNCA,CDK19,ARHGEF9,SYT1,WSCD1,TNS2,TMPO,CABIN1,LMF1,ZNF32,ZNF74,NAV3" Drug 5732_DN Sulfameter [651-06-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "MTUS1,MARK4,SCAPER,LARGE1,FOXN3,CHN2,TAOK2,GIT2,MFAP3L,EDNRA,TAOK3,SCML2,FGF13,SCARA3,KIF2A,CNOT4,PLCD1,STRN3,MAPK3,PTN,TMEM231,RPS6KA2,RXRA,SAFB,MAPK12,TMCC1,FBXW11,CRTC1,ZMAT3,ZNF34,CABIN1,HIRA,VGF,XRCC4,SH3GLB2,MAP3K12" Drug 7534_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "FAM135A,AMPD3,B4GALT6,LHX2,BAG4,SIPA1L1,GREB1,RASGRP1,SUGP2,EGR3,DLC1,ZNF589,FGF12,FLNC,TMEM8B,SEPT9,LYVE1,NXPH3,JAK2,MITF,NFYA,PCDHGC3,PCDH9,SMOX,MINDY2,GDPD2,ZDHHC14,RET,TCP11L1,SGK1,CCDC88A,THSD1,ST5,THRA,TRO,VGF" Drug 5046_DN Pivampicillin [33817-20-8]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ADRA1D,LGR5,CDC14B,TPP1,HOMER3,ARMC8,VCAN,SUGP2,MBNL2,STX2,ZNF589,PRRC2B,GPR37,HSF2,IL6ST,INPP5B,L1CAM,MAPT,NF1,STRN3,PRKAB2,SUGCT,RXRA,ASAP3,PPP4R3A,ELMO2,THSD1,TCF4,KIAA0930,CABIN1,OSBP2,LMF1,TFIP11,MAP3K12,EVI5,KAT6A" Drug 3828_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ASPHD1,ADORA2A,AK2,APBB2,APC,APOC1,CFLAR,KYAT1,CBFA2T2,FOXN3,AKAP7,RCHY1,SH2B1,DMPK,ZNF589,SRCAP,GFER,HNMT,MPP2,ADAM22,LYRM9,PLCD1,PRODH,SNRK,ZSCAN2,TCP11L1,SBF1,SEC14L1,BTBD7,LIMCH1,SPTAN1,ASTN2,EXOC7,PLPPR2,LAT2,ZFP37" Drug 4961_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "PPFIA3,SEMA4G,ALDH7A1,SCAPER,LDLRAD4,CAMK2B,ARHGAP33,SULT4A1,HOMER3,DAPK3,MFAP3L,TMCC2,PLXNC1,MTSS1L,ZMYND10,ZNF589,FHL1,LYVE1,ADAMTS13,GRM8,ATXN2L,SYNPO,KCNH2,MAP2,NNAT,CNOT4,RETREG1,MTRF1L,NLGN1,KDM4B,ARC,SYT5,MCF2L,ICAM5,PARD3,TNS1" Drug 1264_DN Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "CDK13,NCOA1,EIF4G3,CLCN3,SH2B1,OSBPL3,DCAF8,RASGRP2,EZH1,KAT8,ZNF589,FGFR1,FYB1,ERAP1,SESN1,MUM1,AGBL5,KIF2A,GPSM2,PPP5C,SAMD9,PTCH1,GTDC1,DGLUCY,INTS9,CLASP2,STXBP1,PRRC2C,ARHGEF9,FAM208A,TCF4,KAT6B,TNS1,METTL3,ELP5,EVI5" Drug 5525_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ADCY6,BIN1,CDC42BPA,SEMA7A,BACH1,CFLAR,USP2,QKI,CNR1,CNTNAP2,SNPH,RASSF2,MED12,EDIL3,RCAN2,REEP2,FGF1,FGFR1,BAIAP2,SCARA3,ZNF44,POLL,SYNPO,KCNB1,ADAM22,MX1,NOVA1,PLXNB1,PPARA,DIRAS2,ZSCAN32,GTDC1,SH3BP2,ZBTB43,KCNK12,SEMA3B" Drug 3969_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "LTBP4,BIN1,PLA2G4C,BMP7,SGCE,CSF1,RUSC2,DMPK,EDNRA,RASGRP1,EGR3,RASGRP2,PIPOX,F5,AGAP2,FAM49B,SRCAP,GNG4,GPR37,GRIK5,ATXN2L,KCNN1,NPR2,CDK18,PDE1C,PFKFB3,MAPK7,UNC5B,PEG10,IQSEC2,TROVE2,CRTC1,DICER1,VGF,LAT2,SEMA3B" Drug 3284_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ABHD6,NDRG2,CDC42BPA,APC,CDC14B,PPP4R4,PLA2G4C,CDK13,RASL11B,MTMR3,ARHGEF1,FOXN3,AKAP7,CSF1R,BRINP1,EDNRA,ING4,TNK2,TRAF3IP2,ATXN2L,IL6R,NF1,NTRK2,CEP41,PRKAR1B,ELOVL2,FAT4,ASAP3,SLC9A5,SLC11A1,SNCA,SS18,ASTN2,OSBP2,WIPF1,LAMP5" Drug 3785_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "RASL11B,RGS9,CAMK2B,CDO1,CNTFR,ING4,FLT1,GNAO1,GRM8,GSTM5,IGF1,IL6R,KIT,KPNA5,MGAT3,MMP16,CDK18,PPP1R1A,DCHS2,GDPD2,PTN,RET,ABLIM3,PREX2,SLC2A5,ZC3H13,SPART,ATP10B,MCF2L,KLHL4,DOCK9,OBSL1,WIPF1,MAP3K12,EVI5,JPH3" Drug 6827_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "CDC14B,ATP2A2,SYNJ1,GYG2,CACNA1A,CLGN,AKAP7,RCHY1,CRMP1,PDE4DIP,DTNB,FGF1,FGF13,ERGIC3,LYVE1,GLYR1,GPR37,ITGA7,MIA2,NF1,LRP12,GRAMD1C,ELOVL2,RGS4,ZFHX4,KLHDC8A,TCP11L1,SCN8A,CCDC88A,SLC11A1,ARHGAP26,DOCK9,CRTC1,PCDHA3,TNS1,KAT6A" Drug 1707_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "MTUS1,C1QTNF3,LTBP4,FAM131A,CDK13,RIPK1,SYNJ2,CA12,HIP1R,PLEKHB1,WHRN,CRY2,CSF1R,DAPK3,DNM1,SLC12A6,OPTN,CDKL3,VPS26C,GAA,AHDC1,RNFT2,INPP5B,KCNH2,MAP4,RETREG1,PLEC,PPP3CA,PRKAR1B,APTX,DCUN1D2,SYBU,FAM214B,CEP68,IQCE,UBE3B" Drug 1657_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ASPHD1,ABHD6,AK2,CDC42BPA,CFLAR,SOCS6,ENTPD4,CSNK1E,RCAN1,TOM1,ANKMY1,ZNF589,BAIAP2,FAM49B,OGA,SYT17,ZNF276,GRB10,IL6ST,PLCD1,STRN3,LRP12,PPP5C,PRODH,PTCH1,NEK11,ZNF821,ZNF423,IQSEC2,WSCD1,TNS2,ZKSCAN5,VGF,EMSY,MPPE1,SENP7" Drug 2784_DN Retrorsine [480-54-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "APBB2,PPFIA3,SOCS6,HOMER3,BAG4,ENTPD4,HDAC4,HIPK3,COQ7,BAIAP2,GALC,IL6ST,INPP5B,KCNH2,IPO5,MITF,MYO9A,NFYA,NPR2,NPTX1,RETREG1,MBOAT7,PTK2,GSTCD,ANKRD6,ZKSCAN3,COA1,POGZ,SS18,MCF2L,TMPO,PARD3,ZKSCAN5,WIPF1,MPPE1,PHTF2" Drug 4727_DN Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "C1QTNF3,PKP4,APC,PLA2G4C,EIF4G3,CAMK2G,CBFA2T2,MAGI1,CLCN3,JAKMIP2,DTNA,EDNRA,MBNL2,DLC1,FHL1,AFF2,PCLO,IL6ST,LMO2,MAP4,MAPT,KITLG,MITF,NF1,GRAMD1C,SAMD9,ELOVL2,PTK2,GSTCD,FAM214B,KDM4C,PCDHA5,TMPO,CABIN1,RUNDC3B,PHTF2" Drug 6660_DN Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "AMT,APAF1,PDE8B,MARK4,SCAPER,CFAP410,CACNA1A,ARHGEF1,SEPT7,ARHGAP33,VCAN,SGSM2,CDON,CELSR3,MTSS1L,FYN,ZNF44,CRCP,LPAR4,GRM8,HLF,SCIN,GIT1,PRKAR1B,PTN,PTPRH,ATXN7,DZIP1,TROVE2,THSD1,SMG6,SLC44A1,OSBP2,VGF,WIPF1,TIGD6" Drug 5699_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ADAM23,RIMS2,C2CD2L,DRP2,ECM2,EGFR,NRN1,FHL1,FOXF2,AFF2,LPAR4,GPR37,GRM8,TJAP1,INPP5B,KCNH2,MATN3,MMP16,NDP,NF1,PDE4D,NLE1,PPP1R1A,PPP2R2B,PRKCB,PTH1R,ACSM5,BAALC,RASA3,SLC2A5,FAM214B,RBM34,SYN2,CHST5,SEMA3B,SLC17A7" Drug 6272_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "PPFIA3,RIPK1,KIF1A,C5,UBE2L6,SOCS6,PLAA,ARMC8,CSNK1E,DZIP3,DCAF8,GIT2,C2CD2L,PARD6A,CELSR3,CDKL3,EZH1,EFCAB2,FAM49B,GNG4,GRB10,MAP4K5,OGG1,PLXNB1,TMEM231,ZDHHC4,FERMT1,KBTBD4,CDK5RAP2,PBLD,SEPT8,ASTN2,TACC1,TBL1X,CLASP1,KAT6B" Drug 6195_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "RALGAPA1,SEMA7A,CACNA1I,CACNA1G,VAX2,PDE4DIP,DZIP3,SNPH,SEZ6L2,OPTN,MBNL2,EGR3,C3orf18,VPS13B,F5,FGFR1,FHL1,ZNF44,FERMT2,GPD2,PCLO,KCNJ5,ZNF862,CNOT4,OPRL1,PCSK5,PDE4D,SERPINI1,CCSER2,GALNT10,ASAP3,CNKSR2,KDM4B,CDK19,SS18,UBE2H" Drug 3932_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "AMPD3,APC,PPP4R4,MARK4,SLC4A4,CBFA2T2,ARHGEF2,CNTFR,AKAP7,ARMC8,RCHY1,CSF1R,DMPK,DTNA,EDNRA,HIPK3,FCF1,EPB41L2,EZH1,GPER1,SPACA9,CACFD1,HSF2,IL6ST,MAPT,MMP16,ADAM22,NF1,PFKFB2,FNDC3A,ATP10B,ARC,DICER1,TRIO,ZNF24,PHTF2" Drug 7214_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "AP2A2,EPB41L5,PPFIA3,CFLAR,QKI,DZIP3,DBT,LYPD1,SUGP2,TNK2,STX2,VPS26C,BAIAP2,SEMA4D,FAM49B,FYN,MSL3,PRRC2B,BTN2A1,INPP5B,MIA2,MPP2,NCAM2,PCDH9,CCSER2,PLEC,LRP12,RIPOR1,FBXW7,SBF1,EPN2,FNBP1,CABIN1,HIRA,LMF1,ZBTB14" Drug 5954_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "SEMA6A,ARRB1,RGS20,BAIAP3,CA4,RUNX1T1,RAB28,PICK1,CNTFR,SH2B1,CYBB,TBC1D5,RUSC2,PARD6A,DUSP9,EGR3,STX2,ZNF589,EFCAB2,TMEM8B,POLL,GPR37,LMO2,NF1,PFKFB2,MAPK7,ZDHHC14,SBF1,SPART,ATP10B,WSCD1,SZT2,HEY1,LAT2,ZNF24,KCNAB1" Drug 2221_DN Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "OGT,CDK10,CAMK2B,CAMK2G,SCARB1,HOMER3,AKAP7,CSF1,CSF1R,PDE4DIP,SEC14L5,TBC1D5,KIAA0586,CDON,ERBB2,INPP5K,GLYR1,RAB30,GNG4,GRIK5,GSN,MUM1,ICA1,ITPKB,LSS,MYO7A,NPR2,PLEC,ZSCAN2,EMID1,SH3BP2,PEX26,PDZRN3,KDM4B,UNC5B,ZNF74" Drug 954_UP (+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "NDRG2,C1QTNF3,LTBP4,EPB41L5,BCL7A,CFLAR,MTMR2,CACNA1A,NFS1,MAGI1,RAB26,PHF14,ARHGEF4,SLC12A6,CELSR3,IRAK4,FGFR1,FAM49B,GRB10,MBD1,NRCAM,PFKFB2,PPP5C,EMID1,ZFP2,ZNF821,PEX26,PPP4R3A,SLC6A8,ELMO2,MAPKBP1,VPS13A,RPGRIP1L,CDK20,RUNDC3B,EVI5" Drug 7059_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ACTN1,MTUS1,CDC42BPA,CCNT1,TAOK2,AKAP7,NRG2,PDE4DIP,DBT,SEMA4D,POMT1,CINP,CRCP,PADI2,SCIN,MAP2,MEF2C,ADAM22,PPP5C,MAPK7,PRPH,PTX3,TMEM231,SH3TC2,SEC14L1,FUZ,DZIP1,TMCC1,SPTB,SEPT8,TTBK2,RGL1,JMJD6,SYNE1,TNS1,PHTF2" Drug 4232_DN Salsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "APC,SLC4A4,CFLAR,SYNJ2,BAIAP3,TAOK2,TPP1,HOMER3,VCAN,RHOBTB1,DTNA,EDN1,PLXNC1,IRAK4,ING4,MRNIP,MTSS1L,ANKFY1,AFF2,PDLIM5,KCNN1,ADAM22,PIK3R1,RETREG1,SAMD9,ZSCAN32,FAM184A,SMARCD3,KDM4C,UNC5B,SS18,ASTN2,SLC44A1,RUNDC3B,LAT2,SPHK2" Drug 4312_DN Benfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "RALGAPA1,MTUS1,CDC42BPA,CFLAR,SPAG9,KRIT1,SRSF11,ABI3BP,FCF1,ING4,FER,FAM49B,ZNF44,SPIN1,AGFG1,IFI16,IL6ST,MAP4,N6AMT1,NDP,NFIX,ZNF426,STRN3,SLC25A36,KIRREL1,SEC14L1,CCDC88A,BTBD7,ARHGAP26,SS18,TBL1X,TCF4,TRIM2,DICER1,TMPO,ZBTB38" Drug 2467_DN Omeprazole [73590-58-6]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "NDRG2,BIN1,BACH1,RAB33A,IQCK,RCHY1,RCAN1,HIPK3,MBNL2,FHL1,ANKFY1,CELF1,SEPT9,RAB40B,NCKAP1L,TJAP1,ITGA7,JAK2,LSS,MAP4,MEF2C,SCAMP5,GIT1,NFYA,SLC11A2,OGG1,PLCD1,SLC25A23,CNNM2,PTPRN2,MSANTD2,CARF,SAFB,SS18,PCBP4,SENP7" Drug 5077_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.05E-03 1.00E+00 1.44E-02 1.62E-01 36 194 "ASPHD1,ACHE,ADORA2A,AMPD3,GAS7,N4BP2L1,RGS9,KSR1,BMPR1B,IL33,ENTPD2,WHRN,SPOCK3,HS3ST2,DRP2,COQ7,RASGRP2,PIPOX,ARMCX1,SIGLEC8,LPAR4,GPER1,PACRG,MATK,MATN3,PALM,PPARA,GRAMD1C,MASP1,PTPRH,RFX2,TCP11L1,RTN1,PHLDB1,ADGRL3,DOCK9" Drug CID000003559 haloperidol Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 64 394 "ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,OSBPL8,KCNAB2,CACNA1A,CACNA1B,CALM1,CBR1,CCK,KCNAB3,CNR1,COL11A2,DYNC1I1,DTNA,RASL12,HSPA12B,ZMYND10,PPP1R1B,BAIAP2,TRIM16,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,DISC1,NTNG2,TCERG1,LOXL3,MCHR1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,PACSIN2,KCNH2,KITLG,NPY,OPRL1,PDE4B,PDE1B,PDPK1,ABCB1,PPP3CC,PTPRD,QDPR,FOXRED1,SST,VPS13A,SYP,SYT5,MLST8,SLC17A7,KCNAB1,NETO1" Drug CID000048229 talniflumate Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "ADORA2A,CLCN3,PDE4B,PDE4D" Drug CID000037015 cartazolate Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "ADORA1,ADORA2A,ALDH7A1,ZMYND10" Drug CID000133071 Bq 928 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug DB00806 Pentoxifylline Drug Bank 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "ADORA1,ADORA2A,PDE4A,PDE4B" Drug CID000111148 AR45 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "BCHE,HMGCR,KCNH2,MAPK3" Drug CID000190809 CGS 27830 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000019094 lora Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "TBPL1,BOC,AASS,MAT2A" Drug CID000133976 alpha-sialylcholesterol Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "CACNA1A,CACNA1B,CACNA2D1,FGF1" Drug CID006328526 AC1O3HA7 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "MCHR1,SST,SSTR1,SSTR2" Drug CID005311469 TAK-044 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "AGT,EDN1,EDN3,EDNRA" Drug CID000583065 "3,4-dihydroquinazoline" Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "CACNA1I,CACNA1G,CACNA1A,CACNA1B" Drug CID003396482 AC1MQ5W8 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "ACHE,CACNA1I,PAX6,SLC12A2" Drug CID000196897 Bq 153 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000051701 darodipine Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "AGT,APC,CACNA2D1,CALB1" Drug CID000122475 B-31 Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "CREM,EGFR,ERBB2,FCGRT" Drug CID000070194 NPOH Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "AASS,GPD1,GPD2,ADHFE1" Drug CID000134928 4-methylumbelliferyl phenylphosphonate Stitch 2.06E-03 1.00E+00 1.45E-02 1.63E-01 4 6 "PCSK1,PDE4B,PDE4D,ENPP2" Drug ctd:C412815 GW 4064 CTD 2.08E-03 1.00E+00 1.46E-02 1.65E-01 71 446 "KCNH8,C1QTNF3,GAS7,SEMA4G,PPP4R4,NCOA1,ST3GAL5,RUNX1T1,SCARB1,CNTFR,ABI3BP,CSF1R,SNAP91,DOCK2,EDN1,CNNM1,HEYL,RASGRP1,ENPP6,ERBB4,MEGF11,IP6K3,GATM,TTBK1,GSN,UBE2QL1,PADI2,VSIG4,HNMT,LRRC25,ITGAM,GATD1,KIF5A,NCOA7,SMAD9,PIK3AP1,MX1,MYH3,RTL5,CLDN11,PCDH8,ENPP2,DUSP26,SEMA5B,JAKMIP1,NECAB2,FA2H,PPARA,PPP2R2B,LRRN3,MAPK9,STK32A,PID1,LGI2,EMID1,KCNIP3,HKDC1,SLC2A5,LGI3,CDK5RAP2,PDZD2,CLSTN2,APOM,ADHFE1,SATB2,SLC19A3,HIF3A,VWCE,ICAM5,KCNE5,RPRM" Drug CID000003689 ifenprodil Stitch 2.09E-03 1.00E+00 1.47E-02 1.66E-01 17 71 "ADORA1,ADRA1B,ADGRV1,FYN,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNJ5,KITLG,OPRL1,RASGRF1,RASGRF2,UBC" Drug ctd:D024505 Tocopherols CTD 2.10E-03 1.00E+00 1.47E-02 1.66E-01 18 77 "SYT13,CAMK2G,CSF1R,FGF1,FGFR1,CPLX2,CPLX1,GRIA2,PPP3CA,PTPRO,NAPB,SNCA,STX1A,STXBP1,SYN1,SYN2,SYP,TTC3" Drug CID000003496 glyphosate Stitch 2.10E-03 1.00E+00 1.48E-02 1.66E-01 39 215 "LGR5,PTCH2,CHRD,BMP7,BMPR1B,CDO1,TIGD7,NOG,FOXN3,CRYBB1,BOC,KIAA0586,DLX1,GPHN,FGF13,FGFR1,FGFR3,FOXF2,GCK,GLI2,MAP4K5,IGF1,RBPJ,DISP2,LSS,PAX6,PTCH1,PTX3,HKR1,KIF7,SALL1,KIF27,DZIP1,SPP1,TAF9,RIMBP2,WNT7A,ZIC2,ZFP41" Drug CID000492400 NVP & EFV Stitch 2.13E-03 1.00E+00 1.50E-02 1.69E-01 25 121 "NOG,TPP1,ABCG2,CREM,CSF2RA,HDAC9,ABCC5,EGFR,ERBB2,F8,FGF1,FGFR1,FGFR3,FLT1,FOLH1,GRIN2C,GRIN2D,IGF1,PDE4A,PDE4B,PDE4D,ABCB1,PTCH1,VPS13A,ZIC2" Drug CID003467590 STO-609 Stitch 2.14E-03 1.00E+00 1.50E-02 1.69E-01 10 32 "CAMK2B,KRIT1,CD86,CAMKK2,ITGAM,MAPK3,MAPK4,PBRM1,GSTCD,SLC12A2" Drug CID000547450 NSC153858 Stitch 2.14E-03 1.00E+00 1.50E-02 1.69E-01 10 32 "TUBD1,TUBB3,FOLH1,TUBA8,MAP2,MAPT,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000055483 dopexamine Stitch 2.14E-03 1.00E+00 1.50E-02 1.69E-01 10 32 "ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CACNA2D1,KAT8,FOLH1,INPP1" Drug CID000002317 benextramine Stitch 2.14E-03 1.00E+00 1.50E-02 1.69E-01 10 32 "ADRA1D,ADRA1B,ADRB2,AGT,CACNA2D1,P2RX6,DMPK,HP,NPY,P2RX7" Drug CID000022478 IBDU Stitch 2.15E-03 1.00E+00 1.51E-02 1.70E-01 9 27 "ADRA1D,ADRA1B,EDNRA,EDNRB,P2RY1,PRKCB,SST,SSTR1,SSTR2" Drug CID005287911 coformycin 5'-phosphate Stitch 2.15E-03 1.00E+00 1.51E-02 1.70E-01 9 27 "BRAP,AMPD2,AMPD3,BCS1L,F5,ADAM22,NCF2,PPP1R1A,NUDT11" Drug ctd:C080703 SK&F 83959 CTD 2.17E-03 1.00E+00 1.52E-02 1.71E-01 30 154 "NDRG2,CAMK2A,NFS1,SEPT7,CLTB,DPYSL2,DNAJB6,ENO2,TUBA1B,ATP5PD,GLUL,GNAO1,IDH3A,STMN1,TMOD2,SEPT4,PSMA6,QDPR,PTGR2,SIRT2,NAPB,STX1A,SEPT3,NSFL1C,SYN2,PHF24,TUBB2A,UCHL1,DPYSL5,HNRNPA3" Drug 3275_DN Digitoxigenin [143-62-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.17E-03 1.00E+00 1.53E-02 1.72E-01 34 181 "MARCH3,SYNJ2,KRIT1,SOCS6,ARMC8,SMARCAL1,ZNF337,ZBTB24,RHOBTB1,ANKRD46,EGR3,EIF5,IRAK4,ARMCX1,JAK2,MEIS1,SETD4,PDCD2,PIK3R1,PTCH1,ZSCAN32,RAD51D,RGS3,RNASEL,ZC3H14,ZNF302,CEP68,ZC3H4,FAM208A,TRIM2,ZNF23,ZNF45,ZNF184,ZNF189" Drug 4835_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-03 1.00E+00 1.55E-02 1.75E-01 35 188 "AP2A2,AK2,CDC42BPA,ARRB1,ARRB2,RIPK1,SPAG9,KRIT1,DCAF8,FCF1,DLC1,BAIAP2,PDLIM5,MSL3,PRRC2B,HSF2,MMP16,NF1,NFYA,PPP5C,PTK2,PTN,RET,RPS6KA2,CLIP1,ZNF821,ZNF430,ELMO2,SMARCA4,SS18,KANK1,VPS13A,MCF2L,TRIM2,SEMA3B" Drug 5921_UP thioridazine hydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-03 1.00E+00 1.55E-02 1.75E-01 35 188 "APAF1,CDK10,PPP4R4,SYNJ2,CBS,MAGI1,LHX2,TPP1,QKI,PICK1,PDE4DIP,CTH,HDAC9,RUSC2,TOM1,OPTN,MBNL2,ELN,EZH1,FGFR1,MAP2,ADAM22,NCF2,NFYA,POU6F1,CNNM2,PNMA8A,GSTCD,FNBP1,ZHX3,TSPYL2,SYT1,CHST5,VLDLR,WNT7A" Drug 4412_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "APBA2,APC,CFLAR,HAP1,FOXN3,RCHY1,RIMS2,SPOCK2,SUGP2,VPS13B,ERCC2,FGF13,FGFR1,ERAP1,SEPT9,RASSF8,ATXN2L,TJAP1,KIT,TM6SF1,SETD4,PPP2R2B,MAPK7,ZNF821,SMARCC2,RBM34,KDM4C,ZBTB43,MCF2L,HIRA,VIPR2,KCNK12,SPHK2,EMSY,SLC17A7,KAT6A" Drug 3735_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "C1QTNF3,APC,CDC14B,CDK13,SLC4A4,ALDH7A1,C5,CACNA1A,ASIC3,NCOR2,CSF1,RUSC2,SGSM2,FGFR1,SCARA3,SEMA4D,HSF2,IL6ST,MARK1,ZNF862,NELL2,NPR2,PPP5C,BEND5,ZNF821,DOK5,TCF4,SZT2,METTL3,HIRA,VIPR2,ZNF32,MAP3K12,SEMA3B,DPF3,RNF146" Drug 3871_DN Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "APBB2,GAS7,CRLF1,WHRN,NCOR2,USP6NL,HSD17B14,KAT8,ZNF589,FAM49B,GCNT2,RAB30,GPER1,ATXN2L,MAP2,MMP17,CNOT4,NPR2,RETREG1,PLCD1,PPP5C,PRKCB,RAD51D,RGS12,BTBD7,SLC22A4,SMARCD3,LIMCH1,ZBTB43,ARHGEF9,SMG6,KIAA0930,TNS2,THRA,EVI5,ITM2C" Drug 5969_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "TRMT9B,APAF1,PPP4R4,SCAPER,CACNA2D1,SYNGR3,CSNK1E,CNTNAP2,DZIP3,DTNB,TOM1,CNNM1,ELN,PIPOX,DLC1,FGFR1,STON1,CNTRL,TJAP1,KCNN1,MT1M,MAPK10,KCTD17,RPS6KA2,CPEB3,CNKSR2,FAM214B,MYH15,SYN2,IQCE,PCDHA5,THRA,TK2,VGF,KCNK12,NT5M" Drug 1015_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "PKP4,DDO,FAM131A,CA4,CACNA2D1,WHRN,LRIG1,FAM169A,RCAN1,EGR3,IRAK4,POLL,SPACA9,ATXN2L,TJAP1,KCNH2,MATK,LYRM9,ZNF862,PPP2R2B,PTPRE,GTDC1,RGS3,RGS12,TCP11L1,PKNOX2,MAPKBP1,THSD1,TTBK2,RPGRIP1L,TIAM1,R3HDM1,CABIN1,VAV1,VGF,VLDLR" Drug 4157_DN Propylthiouracil [51-52-5]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,AP2A2,C1QTNF3,FAM131A,CDC14B,CFLAR,BMP7,SYNJ1,GYG2,CFAP410,SOCS6,QKI,CRY2,GREB1,ARHGEF4,ZNF589,FHL1,AFF2,SEPT9,AHDC1,ICA1,KCNN2,CDK18,PLCD1,MAPK7,SH3BP2,CPEB3,COA1,MAPKBP1,KIF13A,PLCB1,EXOC7,CABIN1,RUNDC3B,FAM155A,PLPPR2" Drug 6052_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "C1QTNF1,BIN1,PRX,ALDH7A1,CACNA1I,CHN2,EPS15L1,FAM149A,AKAP6,HAPLN1,CSF1,SNPH,FHL1,FYB1,GNAO1,LILRB4,PRUNE2,GRM8,KIT,MID1,PDE1B,ABCB1,PPARA,LRRN3,SAMD9,RASGRF1,RGS12,KANSL3,SLC11A1,ARHGAP26,PHLDB1,WSCD1,TRPM2,ZNF711,AP3B2,JPH3" Drug 3864_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "CDC42BPA,ARRB1,ATP6V0A1,SPAG9,ENTPD6,ZMYM4,SRSF11,SOCS6,TAOK2,HOMER3,BAG4,LRIG1,GPRASP1,ARHGAP32,DAPK3,DTNA,EIF4G1,ZNF589,GLYR1,MIA2,NFYA,PCDH9,RETREG2,GTDC1,GSTCD,RXRA,AP1AR,KDM4C,SPTAN1,ZBTB43,VPS13A,ASTN2,TBL1X,AP4E1,TRIO,PHTF2" Drug 1857_UP Sulindac [38194-50-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "AGT,ALCAM,AMT,CDC42BPA,APC,CA12,SEPT7,ARHGAP33,AKAP7,WHRN,DAPK1,RHOBTB1,EIF4G2,ELN,ERCC2,FGFR1,ANKFY1,AFF2,CAMKK2,DISC1,CSDC2,POLL,GRIK5,PDE4A,PFKFB2,PPP5C,TCP11L1,FUZ,PEX26,DOP1A,SP4,TSPYL2,RPGRIP1L,CDK20,REEP1,MPPE1" Drug 7144_UP Ramipril [87333-19-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BRAP,CRLF1,TPP1,HAPLN1,CNTNAP2,FAM131B,RUSC2,CDON,AASS,ETV1,ZNF589,EFCAB2,ERAP1,GUCY1A1,GUCY1B1,INPP5B,JAK2,LSS,PALM,PPARA,FAT4,GTDC1,ZNF671,MAPK12,ATXN7,SMARCD3,PDLIM2,WSCD1,DNAH7,CABIN1,HIRA,UGT8,WIPF1,LAT2,EMSY,KCNAB1" Drug 2111_DN Methocarbamol [532-03-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BRAP,APBB2,MPDZ,MYRF,RAB28,HINFP,VCAN,PDE4DIP,ARHGEF4,INTS1,RUSC2,C2CD2L,RHOBTB1,BAIAP2,MPP6,GAD1,SLC2A6,MAN1B1,KHK,MAP4,MX1,CCSER2,SLC25A23,BCAS3,FAM102A,ASAP3,AMBRA1,ARHGAP26,SPTAN1,ZEB1,PARD3,CABIN1,PLPPR2,LMF1,VPS35L,MPPE1" Drug 5256_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,APOC1,ARSE,BAIAP3,RUNX1T1,USP2,CNR1,PDE4DIP,HDAC9,MFAP3L,C2CD2L,ERCC2,SCARA3,TRMO,FUT9,GABRG2,GSN,ICA1,ITGA7,KCNN1,MSI1,ADAM22,SLC11A2,PLCD1,MBOAT7,MAPK7,FAT4,ZNF821,STX1A,ZEB1,SLC35G2,RIMBP2,CDK20,FAM155A,UBE2H,UBE3A" Drug 3583_DN Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "GAS7,BCAS1,PPFIA3,ARRB1,CFLAR,GYG2,RAB29,SCARB1,SOCS6,PLAA,VAX2,CREM,ENTPD4,GIT2,JAKMIP2,C2CD2L,PARD6A,CELSR3,ENO2,COQ7,EFCAB2,TPK1,PRELID3A,TDRKH,KITLG,MID1,MPP2,ADAM22,PPP3CC,EMID1,ANKRD6,ST5,EXOC7,DICER1,CABIN1,VAV1" Drug 3246_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "MTUS1,C1QTNF3,RGS20,SYNJ1,TAOK2,SIPA1L1,MFAP3L,DTNA,FCF1,PLEKHA1,RRAGB,IQCG,STON1,BTN2A1,IPO5,TM6SF1,MIA2,KITLG,NF1,SLC11A2,CEP41,CNNM2,TCP11L1,RBM34,TSNAXIP1,TROVE2,NXT2,ELOVL4,ARHGEF9,ZNF34,TMPO,BEX4,ZBTB14,ZNF24,PLSCR4,PHTF2" Drug 3427_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "SRPX,CDC14B,ATP6V0A1,CFLAR,ST3GAL5,GYG2,FOXN3,TPP1,DZIP3,GREB1,DOCK4,DCAF8,RCAN1,DUSP9,HSD17B14,OGA,GALC,INPP5K,MALT1,GNG4,KITLG,ADAM22,NF1,CNOT4,PLTP,PLXNB1,PTPRE,RGS12,GSTCD,SEC14L1,FAM214B,EXOC7,NDRG4,DNALI1,MPPE1,EPM2A" Drug 838_UP 5248896; Up 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASIC1,PDE8B,ST3GAL5,ARHGEF1,SCARB1,AKAP7,SIPA1L1,ARHGEF4,GIT2,DBT,DTNA,MAMLD1,CNNM1,EIF5,EFCAB2,TRMO,POLL,DIDO1,GRM8,GSN,HNMT,LIG4,LYRM9,SETD4,RGS12,TRAPPC13,FNDC3A,SLC22A4,ZKSCAN3,SPART,PLCB1,ZNF34,TK2,REEP1,EPM2A,ST7" Drug 5873_UP Nadide [53-84-9]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "PKP4,APC,ATP6V0A1,ST3GAL5,KCNAB3,RAB26,AKAP7,PCYT1B,FAM149A,DTNA,HSD17B14,DENND4A,REEP2,FCGRT,ZNF589,CGREF1,HPGDS,POLL,PRRC2B,MAPT,NPTX1,MAPK10,KLK6,SAMD9,BCAS3,PTPRH,ASAP3,TSNAXIP1,TCF4,PCDHGA10,CABIN1,HIRA,LMF1,WIPF1,XRCC4,SPHK2" Drug 1688_DN Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ADCY6,AP2A2,AK2,CDC42BPA,CDK10,ARRB2,NUMB,BMP7,SCARB1,HOMER3,PPP6R2,KIAA0586,SGSM2,DMPK,KAT8,TRMO,SEPT9,DHX35,KCNH2,MAP4,MAPT,MIA2,SCAMP5,GIT1,NFYA,SETD4,STRN3,CNNM2,ATXN2,SH3BP2,ZSWIM8,SS18,ELOVL4,PHLDB1,EXOC7,SEMA3B" Drug 2464_DN Probenecid [57-66-9]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BIN1,KCNAB2,CDK10,ARRB1,BACH1,SLC25A14,SCARB1,QKI,CREM,PLXNC1,TUBD1,NCALD,KAT8,ZNF589,ATXN2L,TJAP1,MAP4,SCAMP5,AFF1,ZNF862,NF1,SETD4,NLE1,PLCD1,RNASEL,SEC14L1,CCDC88A,TROVE2,TCF4,SZT2,CRTC1,CBX5,TMPO,UBTF,FLRT2,PHTF2" Drug 1521_DN Cyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "GAS7,FAM131A,CFLAR,CBFA2T2,FOXN3,SLIT2,CLCN3,GIT2,FBXL5,TMCC2,CNNM1,SYT17,INPP5K,COPS8,GLYR1,RAB30,GNG4,MAP4K5,PADI2,DHX35,MPP2,GIT1,SLC11A2,SETD4,RETREG1,TRAPPC13,SBF1,ZNF821,PPP4R3A,BTBD7,POGZ,IQCE,TNS2,TMEM121,PARD3,GDPD5" Drug 3828_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,TRMT9B,APBA2,MTMR3,CAMK2B,SULT4A1,PICK1,CNTN1,SNCAIP,GREB1,TMCC2,EDNRB,RASGRP2,STX2,ERCC2,PIPOX,FGFR3,RUNDC3A,GPER1,HLF,ITGAM,PACRG,KITLG,MMP16,ZSCAN32,PID1,KCNIP1,CPEB3,RBM34,TBCEL,PIK3R5,CHST5,TRIO,PRDM10,EPM2A,KAT6A" Drug 4470_DN Cyproterone acetate [427-51-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "RALGAPA1,AP2A2,APBB2,CFLAR,SCAPER,AKAP7,SLC4A8,AATK,DMPK,ING4,ETV1,EZH1,FGFR1,CINP,FYB1,INPP5K,SYNPO,MAPT,GIT1,MX1,ZNF426,SNRK,PID1,SLC25A36,ASAP3,BTBD7,ZNF667,COA1,TMCC1,SYT1,TK2,BEX4,HIRA,ZNF24,UPF3A,URM1" Drug 2446_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASIC1,ADRA1D,APC,SYNJ2,CAPN3,PLAA,ARHGEF10,CSNK1E,DGKG,ING4,PCOLCE2,CDKL3,F5,ZNF589,SEPT9,INPP5K,GATM,LPAR4,SPACA9,MAN1B1,AGBL5,MAP4,N6AMT1,MAPK10,TMEM104,ZNF493,ZDHHC14,EMID1,SH3BP2,PEX26,DDN,JMJD6,ADGRL3,THRA,LMF1,FTSJ1" Drug 3392_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,BIN1,PPP4R4,SYNJ2,MTMR3,GYG2,C5,USP2,ARHGEF2,ARHGEF6,PICK1,SLC4A8,ELN,VPS13B,SPEG,IQCG,SEMA4D,GLYR1,IL6ST,INPP5B,MMP16,LYRM9,OGG1,NLE1,PPP2R2B,MAPK7,RASA3,ZKSCAN3,SNCA,ARHGAP26,THSD1,EXOC7,TK2,REEP1,MAP3K12,KAT6A" Drug 6691_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ADD2,APAF1,APBB2,APC,ARRB1,CACNB4,DLGAP1,CACNA2D2,TAOK2,HAPLN1,MFAP3L,SV2B,DTNB,FRY,ING4,ZNF391,EYA1,ZNF589,SIGLEC8,GLI2,GRIK5,SOX21,TAGLN3,NEFH,PPP1R1A,PRKAR1B,CARF,OGDHL,ARHGAP26,WIPF1,KCNK12,ZNF74,SPHK2,LAMP5,ZNF225,SENP7" Drug 1549_UP Clotrimazole [23593-75-1]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ANK2,APAF1,STX16,CARS,ARHGAP33,CTH,GSDME,DYNC1I1,ANKRD46,ZNF589,TMEM164,EVL,GABRG2,NEU3,PCDH17,DIDO1,FICD,KCNH2,MX1,MYT1,NEFH,PDE1C,GPSM2,MBOAT7,CNNM2,CEP97,RNASE1,RNASEL,ZNF671,ASAP3,R3HDM2,GLT8D1,ZC3H13,MLST8,TPM1,TRPM2" Drug 2523_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,KCNAB2,ZBTB10,CFAP410,C2CD2,ARHGEF10,SIPA1L1,DCAF8,RASGRP2,CD320,ACSL4,TPK1,USP19,TXNL4A,LILRB4,LILRA2,GRM8,IRF8,MYT1,MBOAT7,C1orf109,RAD51D,FBXO11,ARHGEF40,KBTBD4,DDN,PBLD,KANK1,NSFL1C,TK2,TNS1,UBTF,LAT2,XRCC4,ZNF142,CIAPIN1" Drug 6157_UP Kaempferol [520-18-3]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "SPARCL1,APBB2,SEMA4G,LDLRAD4,CFAP410,RUNX1T1,CDH2,CREM,DGKG,E2F5,EGR3,ING4,CDKL3,SH3YL1,IQCG,SRCAP,TDRKH,SCIN,KCNB1,NRCAM,PDE4D,LRP12,CNNM2,ST6GAL1,SLC2A5,PKNOX2,CXXC4,SPTAN1,TSPYL2,PHLDB1,SYT1,DMXL2,TK2,LMF1,MKRN3,GAN" Drug 1815_UP Sulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG3,BIN1,KCNAB2,ADGRB2,CFLAR,CDH2,ZMYM4,CNOT8,AKAP7,PREPL,SPOCK3,E2F5,FCF1,APH1A,USPL1,ETV1,USP21,DLL3,OGA,ARFIP1,ATXN2L,INPP5B,MBNL1,ZFYVE21,CNNM2,RAP1GDS1,SS18,SYN2,TRIM2,TNS2,SLC35G2,TMEM121,METTL3,TRIO,FIP1L1,ST7" Drug 4234_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ALK,TRMT9B,AMPD3,CDK10,ALDH7A1,ST3GAL5,BAIAP3,CFAP410,CAMK2B,CBFA2T2,VCAN,FCF1,COQ7,ETV1,TRAF3IP2,TMEM8B,USP19,HNMT,MATN3,CNOT4,PFKFB2,SLC25A23,POLG,PTPRB,FAM184A,ZNF821,KIF13A,RBM34,TSNAXIP1,DOK5,SPTAN1,CDK19,SS18,TRIM2,THRA,VGF" Drug 7327_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "CDC42BPA,APOC1,PPFIA3,NCOA1,HOMER3,AKAP7,BAG4,CREM,DTNA,CDKL3,SCML2,INPP5K,GLYR1,LIG4,MAP4,MATK,KITLG,STRN3,PRKAB2,TMEM231,CEP97,ACSS3,RGS3,CLIP1,FERMT1,EPN2,ZSWIM8,THSD1,ARHGEF9,DNMBP,PARD3,VGF,TFIP11,FIP1L1,SMIM8,AAAS" Drug 5451_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "AP2A2,ANK2,GAS7,PPP4R4,RGS20,CFLAR,LDLRAD4,CAMK2B,SLC16A4,CHRNA4,LRIG1,ARHGEF4,MYEF2,EGFR,AASS,ING4,STX2,C2orf72,MAP4,LRP1B,NF1,CEP41,MAPK7,C1orf54,ZFHX4,MRAS,FAM214B,CDK19,SSTR1,TK2,TNS1,UCHL1,FLRT2,XRCC4,SLC30A3,KCNAB1" Drug 7460_DN Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BRAP,AK2,CDC42BPA,PPFIA3,NUMB,CFLAR,CAMK2G,ARHGEF1,NECTIN3,DZIP3,ZNF337,MFAP3L,MAMLD1,SEPT9,GRB10,SLC2A6,HNMT,JAK2,MPP2,PRODH,CNNM2,TMEM231,FAM184A,RXRA,SMARCC2,KDM4B,ARHGAP26,ZBTB43,CEP68,NSFL1C,CABIN1,VGF,ZBTB14,FTSJ1,ST7,SMIM8" Drug 5315_DN Danazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BRAP,ARRB2,NCOA1,ADAM15,C2CD2,CREM,APPL1,RUBCN,ZNF337,EXOG,PLEKHA1,ANKFY1,TRMO,FAM49B,SEPT9,MSL3,GPR37,RNFT2,MYO9A,PCDH9,PRKACB,PKIA,MCMBP,INTS9,RCOR3,SP2,ZSWIM8,CLASP2,TACC1,PJA1,EXOC7,AGTPBP1,UBTF,VGF,ZNF184,TFIP11" Drug 5702_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "APBB2,APC,EPB41L5,PPP4R4,ALDH7A1,KIF1A,CA4,B4GALT6,RAB28,HOMER3,SIPA1L1,DZIP3,DAPK3,SPOCK2,ARMCX2,PARD6A,RCAN1,TOM1,STX2,BAIAP2,POLL,CNTRL,LSS,MMP16,MPP2,ADAM22,NF1,SAMD9,TMEM104,RIPOR1,CEP97,ASAP3,FUZ,TBCEL,WSCD1,PHTF2" Drug 6174_DN prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,ADD2,APOC1,CASK,KIF1A,BMP7,SOCS6,RAB28,OSBPL3,PPP1R16B,NR1D2,RASGRP2,PTK2B,FECH,ANKFY1,ATXN2L,ITGA7,MAP4,NF1,SLC11A2,PDE4B,TCP11L1,ZNF821,AMBRA1,SLC11A1,SLC22A4,KDM4C,EXOC7,TCF4,TNS1,TSC2,UBTF,FLRT2,PLPPR2,ZNF225,NLRP3" Drug 3747_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "AP2A2,TRMT9B,ARHGDIG,CDK13,ADAM23,KALRN,CDO1,SULT4A1,ERC2,MRNIP,NCALD,OLFM1,RAB30,GNAO1,ADAMTS13,KCNN1,MAN2A2,MBP,ADAM11,MMP17,ADAM22,MT1M,LYRM9,NPTX1,ENPP2,MAPK10,PTPRD,KCNIP1,SH3BP2,PKNOX2,FAIM2,IZUMO4,TLR4,AMACR,TRO,KCNAB1" Drug 2132_UP Xylazine [7361-61-7]; Up 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ADORA1,ARHGDIG,GYG2,AKAP7,CPS1,RIPOR2,RUSC2,PARD6A,MBNL2,MTSS1L,STX2,F5,HPCAL4,NBEA,ALDH1L1,GFER,RUNDC3A,KHK,MAP4,MEF2C,MYO7A,EPB41L4B,PPP2R2B,RIPOR1,FAT4,GAL3ST4,ZNF821,MYH15,TBCEL,OBSL1,TK2,ICAM5,CDK20,RUNDC3B,UCHL1,ZFP37" Drug 3455_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASIC1,APBB2,LDLRAD4,SEPT7,ASIC3,STOML1,LY86,PICK1,AKAP7,ENTPD4,CSF1,TMCC2,STON1,KCNN2,KIF5A,KIT,MAP4,MITF,ZNF862,NF1,KHDRBS2,GTDC1,TCP11L1,SUPT20H,BTBD7,ZHX3,IQSEC2,PHLDB1,ARC,SYN2,ZEB1,CRTC1,VGF,VLDLR,SLC30A3,KCNAB1" Drug 3295_DN Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASPHD1,AK2,APOC1,PPFIA3,ARRB1,MARK4,ARHGEF1,CACNA2D2,RAB28,LRIG1,SOCS5,DBT,FGFR1,FGFR3,MSL3,TDRKH,DIDO1,ACOT7,HNMT,INPP5B,JAK2,MBD1,KITLG,LYRM9,NEK1,NF1,PLEC,FAM184A,TRAPPC13,SUPT20H,SH3BP2,PLCB1,CHST8,PLPPR2,XRCC4,PCBP4" Drug 7406_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASPHD1,ADRA1D,AP2A2,ALK,CDK10,ADAM23,ARHGEF6,SIPA1L1,VCAN,HDAC4,C2CD2L,EGFR,FGFR1,ALDH1L1,TJAP1,ITGAM,KCNB1,KIF2A,PALM,PCDHGC3,PCDH9,MBOAT7,PTN,RIPOR1,RGS12,MRAS,LIMS2,FAM214B,PKNOX2,SNCA,CDK19,ANKRD12,PCDHA5,ZBTB14,HPS4,UBE3B" Drug 3124_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "BIN1,CDC42BPA,FAM131A,BMP7,CAMK2B,SULT4A1,COL9A3,CPS1,SH2B1,AATK,DCAF4,USP6NL,SV2B,EDNRB,CELSR3,TNK2,SRCAP,PCDH17,KIFC3,MARK1,TAGLN3,LYRM9,CNOT4,NOVA2,MAPK10,RELN,BCAS3,PTCH1,PTPRD,ZDHHC14,PREX2,SLC11A1,BTBD7,ZBTB43,KANK1,SZT2" Drug 3409_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "AP2A2,EPB41L5,CDK10,BCL7A,CFLAR,NCOR1,LRIG1,TM9SF4,C2CD2L,DTNA,FGFR1,FAM49B,MAP4,MAPT,PDE4A,CNNM2,CEP97,FAM192A,AMBRA1,NUBPL,PEX26,PPP4R3A,EPN2,ARFGAP1,SPATA7,ZC3H13,ZBTB43,LHPP,TROVE2,SS18,ARHGEF9,ANKRD28,MCF2L,HIRA,PLPPR2,XRCC4" Drug 2199_DN Myosmine [532-12-7]; Down 200; 27.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,APAF1,ARRB1,BACH1,SYNJ1,SLC25A14,CD86,HOMER3,CSF1,PDE4DIP,DAPK3,RCAN1,EIF1,TUBD1,COQ7,RASGRP2,GALC,POLL,ITGA7,KPNA5,LIG4,MAP4,ZNF862,NINJ2,PILRA,RIPOR1,RNASEL,TMCC1,NXT2,FBXW11,NSD1,TMPO,PARD3,ZNF32,PHTF2,SENP7" Drug 4386_DN Rescinnamin [24815-24-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "APLP1,CDK13,PDE8B,SLC4A4,CFLAR,MTMR2,CRLF1,FOXN3,TAOK2,AKAP7,RCHY1,SIPA1L1,PDE4DIP,SPOCK2,DMPK,BAIAP2,EFCAB2,FAM49B,MALT1,RUNDC3A,GNG4,GSN,ATXN2L,MATK,KITLG,PPP5C,FNDC3A,COA1,PLCB1,ARC,DICER1,FLRT2,LMF1,SEMA3B,ST7,KAT6A" Drug 3266_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "MTUS1,APBB2,PPFIA3,PPP4R4,DNAH17,CACNA1I,BAIAP3,B4GALT6,TAOK2,ENTPD4,BRINP1,DTNA,FCF1,ZNF589,PDLIM5,CAMKK2,DISC1,GLYR1,MSL3,GRB10,INPP5B,MAPT,KITLG,ADAM22,NF1,PALM,SLC25A23,PLTP,MBOAT7,KCTD17,SH3BP2,PLCB1,ARC,PCDHA5,TMPO,VGF" Drug 5636_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "KDM5D,ADD2,SPARCL1,BEGAIN,APLP1,ARHGDIG,LDLRAD4,PICK1,CRMP1,ARHGEF4,RASSF2,DGKG,SPOCK2,C2CD2L,HIPK3,EGR3,FGF13,PDLIM5,POLL,HLF,MMP17,NOVA2,C19orf57,MAPK7,RGS4,KCNIP1,SH3BP2,SNCA,KDM4B,CDK19,SYN2,SYT5,TAL1,WSCD1,CLIP2,ITM2C" Drug 4707_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASPHD1,ADORA2A,BIN1,CFLAR,SCAPER,CREM,BRINP1,RUSC2,DTNA,EDNRA,MBNL2,AASS,ING4,COQ7,ACSL4,ZNF589,FYB1,TXNL4A,MSL3,GNG4,GRB10,IL6R,NF1,NFYA,PPP2R2B,ELOVL2,RGS12,RPS6KA2,ANKRD6,ZKSCAN3,SNCA,ARC,TRIM2,CRTC1,DNALI1,EVI5" Drug 1478_DN Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "FAM131A,ARRB1,CFLAR,KYAT1,TAOK2,VAX2,HOMER3,DZIP3,DTNA,HIPK3,SUGP2,IRAK4,FKTN,KAT8,ZNF589,FAM49B,CNOT4,NPR2,SLC11A2,PRPH,APTX,SBF1,BTBD7,MAPKBP1,KDM4B,CEP68,EXOC7,ZNF34,BEX4,PARD3,HIRA,ZNF74,TFIP11,MAP3K12,SEMA3B,EPM2A" Drug 3875_DN Quinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ASIC1,AP2A2,KCNAB2,ARRB1,SLC4A4,CFLAR,CLGN,NCOR2,CSNK1E,SIPA1L1,PARD6A,DMPK,SLC12A6,DUSP9,ZNF589,FER,FGF12,FHL1,GLYR1,MAP2,KITLG,MMP17,NEK1,NF1,PLCD1,GSTCD,IQSEC2,ARHGEF9,KIAA1107,CHST8,ZNF34,TK2,KCNK12,ZFP37,ITM2C,SENP7" Drug 4103_DN Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "LTBP4,SCAPER,GYG2,STOML1,DBN1,SUGP2,ING4,ZNF589,PRKAG2,FHL1,SEMA4D,TRAF3IP2,GAD1,DISC1,GLYR1,RAB30,ELOVL5,IL6ST,INPP5B,KCNH2,LSS,KITLG,MPP2,ADAM22,NEK1,NFYA,CNOT4,PLCD1,PTPRO,FUZ,CLSTN2,THSD1,TNS2,ZNF34,CABIN1,ZBTB14" Drug 5265_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "MARK4,CFLAR,SYNJ2,CA8,CRY2,NCOR2,RIMS2,DMPK,EGR3,MTSS1L,FGFR1,NSG1,POLL,IL6ST,KCNB1,KCNH2,LSS,MAP4,AFDN,NF1,NPR2,CLDN11,PLTP,CEP41,RIPOR1,ENOX1,RGS12,SEMA6D,ZNF821,SLC2A5,PKNOX2,SYT5,EXOC7,DMXL2,FLRT2,PARP11" Drug 1303_DN Arecoline hydrobromide [300-08-3]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG2,BRAP,ARNTL,STX16,FOXN3,CNOT8,HOMER3,PREPL,C2CD2,PPP1R16B,CTH,DTNA,FEM1B,EPB41L2,PCYOX1,GLUL,LILRB4,HSF2,INPP5B,KIF2A,MBNL1,ZFYVE21,MINDY2,GTDC1,SLC2A5,CCDC88A,SS18,NXT2,SYPL1,TLR4,TMPO,NR2C2,TSN,CLDND1,REEP1,MPPE1" Drug 6616_DN "Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "CDK13,PDE8B,MARCH3,MARK4,SCARB1,PLAA,HOMER3,ARMC8,WHRN,CPS1,NCOR2,EXOG,MRNIP,ZNF549,DENND2A,SRCAP,SCAMP5,AFDN,ZNF862,FA2H,PRKAR1B,EPN2,ELMO2,KDM4B,ARHGAP26,IQSEC2,DDN,POGZ,ST5,DIP2A,SUPT5H,KIAA1107,TFIP11,HPS4,VPS35L,UBE3B" Drug 4531_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ACHE,SYT13,CDC42BPA,ADAM23,CFLAR,CAMK2B,RUNX1T1,SEPT7,PCYT1B,CRY2,RIPOR2,SPOCK3,F5,DCTN2,SYT17,GPER1,GRM8,GSN,HLF,FAM69A,JAK2,MMP16,NEFM,PDE4D,PLCB2,PTPRN2,NEK11,SCN8A,KANSL3,SLC11A1,DOP1A,ADGRL3,TIMP4,SSBP2,LAT2,SH3GLB2" Drug 311_UP monastrol; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ABHD6,BIN1,KCNAB2,CDK10,ARRB1,ARRB2,ATP6V0A1,BAIAP3,HOMER3,SH2B1,ARHGEF10,GIT2,SUGP2,STX2,ERCC2,RUNDC3A,RNFT2,ATXN2L,ITPKB,KHK,L1CAM,ADAM22,PRODH,WDR25,SUSD4,GALNT10,FERMT1,ABLIM3,KDM4B,NMNAT2,UNC5B,SEPT8,TRIO,PLPPR2,MAP3K12,MPPE1" Drug 2792_DN Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "APOC1,MARK4,HAP1,USP2,ARHGEF2,FAM189A2,CSF1,CSF1R,CSNK1E,JAKMIP2,ZNF804A,FEM1B,FGFR1,BAIAP2,TPK1,SRCAP,USP19,CACFD1,RASSF8,ATXN2L,IL6ST,KCNH2,LMO2,MPP2,ZNF862,PRKAR1B,APTX,BTBD7,COA1,SS18,EXOC7,DMXL2,NSD1,TMEM121,TK2,GDPD5" Drug 5299_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ACTN1,NME5,BIN1,APBA2,FAM131A,C5,HIP1R,ARHGAP33,STOML1,GREB1,GIT2,ZNF804A,BAIAP2,OGA,ZNF276,GLYR1,FERMT2,MIA2,NFYA,NTRK2,PFKFB3,MTRF1L,MAPK3,PREX2,FAM214B,CDK5RAP2,SOX3,ZHX3,CLSTN2,POGZ,ELOVL4,PLCB1,CABIN1,KLC2,HPS4,KAT6A" Drug 2663_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NDRG3,DOC2A,MPDZ,HIP1R,SLITRK5,PPP1R16B,DAPK3,CDON,TOM1,ERBB2,ZNF44,ERAP1,SEPT9,ALDH1L1,RUNDC3A,ZNF276,MAPT,MYO6,PLCB2,PMP22,PPARA,MAPK7,RIPOR1,KHDRBS2,RXRA,SCN2B,FAM102A,AMBRA1,NLGN1,FAM214B,ARHGAP26,TROVE2,EXOC7,TRIO,LMF1,PCBP4" Drug 1527_DN Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "ADD1,PPFIA3,CFLAR,SCAPER,CAMK2G,SOCS6,SULT4A1,NCOR1,DCAF8,DTNA,OGA,SYT17,USP19,RAB30,GNG4,CNTRL,MAPT,GIT1,NEK1,CNOT4,SETD4,NLE1,FAM192A,ZNF821,SH3BP2,ANKRD6,CEP68,PLCB1,IQCE,KIAA0930,TRIM2,VGF,VIPR2,ZNF74,REEP1,EPM2A" Drug 6129_DN Piperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "CDC42BPA,PKP4,SYNJ1,CAPN3,ARHGAP33,PLAA,ENTPD4,DBT,RCAN1,HIPK3,FCF1,SUGP2,TNK2,ENO2,RASGRP2,ADAM28,NCKAP1L,ICA1,MIA2,NEK1,GPR85,STRN3,MBOAT7,TCP11L1,MAP6D1,TRA2B,SLC11A1,SNCA,SS18,DNMBP,TMPO,TNS1,ZKSCAN5,HIRA,XRCC4,MARCH8" Drug 3050_DN Crotamiton [483-63-6]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "RALGAPA1,APBB2,FAM131A,DNAH17,MARK4,HIP1R,RAB33A,STOML1,EXOG,MBNL2,DLC1,PDLIM5,POLL,GSN,PADI2,MAP4,MEF2C,MYO6,GPR85,SLC25A23,WDR25,PTCH1,RBBP6,NEK11,ZNF821,RASA3,FAM214B,SNCA,SPTAN1,ATP10B,TRPS1,PLPPR2,ZBTB38,ZNF225,KCNAB1,KAT6A" Drug 2225_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.24E-03 1.00E+00 1.56E-02 1.75E-01 36 195 "NME5,APLP1,PDE8B,PTCH2,ATP2B2,CFLAR,BAIAP3,CAMK2B,AKAP6,CNTNAP2,MAML1,RUSC2,DNAH9,HIPK3,VPS13B,MTSS1L,OGA,SIGLEC8,LYVE1,IRF8,ITGAM,KCNQ3,MBD1,MEF2C,PURG,LRP12,PRKCB,PTPRO,SATB1,PKNOX2,SLC11A1,LIMCH1,HECW1,PEG10,PLSCR4,DPF3" Drug CID000005212 sildenafil Stitch 2.26E-03 1.00E+00 1.57E-02 1.77E-01 21 96 "PDE8B,ALDH7A1,CACNA2D1,RHBDL1,CNGA3,ABCC5,EDN1,EDNRA,EDNRB,CIT,GUCY1B1,NPR2,PDE1C,PDE4A,PDE4B,PDE4D,PDE1B,MAPK3,MAPK4,MAPK7,SEPT3" Drug CID005310996 ADP beta S Stitch 2.26E-03 1.00E+00 1.57E-02 1.77E-01 21 96 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,APC,CACNA1B,P2RX6,ENTPD2,PLCXD3,LPAR4,PLCD4,HNMT,MAT2A,P2RY13,P2RX7,P2RY1,PLCB2,PLCD1,PLCB1,P2RY12" Drug CID000002376 AC1Q3ZOL Stitch 2.27E-03 1.00E+00 1.57E-02 1.77E-01 45 258 "ADORA1,ADORA2A,APOC2,BCS1L,CACNA2D1,CALB1,CCK,SOCS6,CHRNA4,CLCN3,CNR1,BOC,DBI,DMPK,MED12,DTNA,GPHN,STX2,ADGRV1,CSPG5,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNN3,MEST,NPY,OPRL1,PTCH1,GLDN,SLC6A11,SLC12A2,SST,JMJD6,MLST8,ZEB1,ACTR6" Drug ctd:D007545 Isoproterenol CTD 2.28E-03 1.00E+00 1.58E-02 1.78E-01 147 1034 "ACADM,ADCY5,ADCY6,CCDC85A,TMCC3,ADRA1B,ADRB2,AGT,SORCS2,ADGRF5,ARHGAP20,MYH7B,APAF1,PHYHD1,SHROOM2,ARNTL,ARRB1,ARRB2,ATP2A2,N4BP2L1,CA4,HAP1,CAMK2B,CH25H,SPAG9,CD38,CDH2,CDO1,CRLF1,CLCN3,ABCG2,MYRIP,CPS1,CREM,GDA,VCAN,ARHGAP24,SPOCK2,PITPNC1,HEPH,DMD,EDN1,EDNRA,EDNRB,HIPK3,TMTC1,FRY,EGFR,ELN,CALCRL,DENND4A,EZH1,TUBA1B,FCGR3A,FGFR3,TMEM164,FHL1,FOXO3,FLT1,RASL10A,OGA,GALNT15,GCNT2,TUBA8,SESN1,CSDC2,GGT5,PPARGC1A,LYVE1,GLUL,STON1,PSIP1,IRAK3,HLF,HMGCR,AGBL5,HSPA1L,SMAP1,IFI16,IGF1,IL12A,ITGAM,ITPKB,KCNB1,KCND2,LAMA2,PACRG,SMAD1,MBD1,MEF2C,ADAM22,MSR1,MYCN,MYO5A,NCF2,NUCB2,PDE4A,GNG2,ABCB1,PIK3R1,PKM,SH3KBP1,PPARA,RASGEF1B,PRKCB,MAPK3,PRODH,PTH1R,PTPRD,PTX3,PEX2,QDPR,KLHDC8A,PCMTD2,FBXW7,CLIP1,SCN7A,PPM1E,ABLIM3,SLC8A1,MBD5,SPP1,TROVE2,NXT2,KLHL7,SYN2,MCF2L,CUX2,DOCK9,HIF3A,THRA,TIAM1,TIMP4,TLR4,R3HDM1,TPM1,ZNF346,PPIL6,TUBB2A,UBC,UCHL1,TBC1D15,KCNT2,SPHK2,REEP1,INTS3,RNF103" Drug CID000005987 sulfamate Stitch 2.28E-03 1.00E+00 1.58E-02 1.78E-01 14 54 "SLC4A4,CA4,CA12,CALM1,NPIPA1,SLC12A6,MEST,PTCH1,PTPRB,FBXW7,SLC12A2,SLC12A4,P2RY12,ST8SIA2" Drug CID000004584 AC1L1IHP Stitch 2.29E-03 1.00E+00 1.59E-02 1.79E-01 108 729 "AGT,MYH7B,CDK13,ALDH7A1,KIF1A,CFLAR,CACNA2D1,CALM1,CAMK2B,CAST,RUNX1T1,CCK,KRIT1,RGN,LRBA,CDC25B,MYL6B,CREM,NCOR1,CSNK1E,CSNK1G3,PPP6R2,DAPK3,B3GAT3,RASA4,TUBD1,SPEG,RPS6KC1,TUBB3,PPP1R1B,FOXO3,IQGAP2,INPP5K,CPLX2,GCK,TUBA8,MSTN,CSDC2,KCNMB4,TNFAIP8L3,CPT1C,MYLK2,IGF1,KCNK3,KIF2A,KIF5A,KIFC3,ASPRV1,MAP2,MAPT,MBP,PPM1L,NEFM,NF1,PDE3A,PDPK1,ABCB1,PIK3C2A,PIK3R1,ZNF655,PLIN1,STRN3,PPM1B,PPP1R1A,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,PPP5C,PRKACB,PKIA,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PSMA6,PTK2,PTPN13,PTPRD,PTPRN,PPP2R3C,KIF7,GSTCD,RPS6KA2,MAPK12,SMPD3,KIF27,KIF21A,KIF16B,SLC12A4,KIF13A,SPP1,STAU1,SYN2,SYT1,TK2,ACTR6,CABIN1,TSC2,TUBB2A,TUBB1,UBTF,GORASP1,VLDLR,MAP3K12,TUBA1A" Drug 3443_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.30E-03 1.00E+00 1.59E-02 1.79E-01 32 168 "RALGAPA1,SRPX,DOC2A,ADAM15,CFLAR,ST3GAL5,CDO1,CLCN3,TPP1,MAGED1,DCAF4,TBC1D5,DTNA,FEM1B,OPTN,EGR3,ACSL4,FHL1,PDLIM5,INPP5K,SLC2A6,HMGCR,LSS,KITLG,MINDY2,CNNM2,PTPRE,TCP11L1,PARD3,FLRT2,VGF,VLDLR" Drug ctd:C049325 "1,2-dithiol-3-thione" CTD 2.31E-03 1.00E+00 1.60E-02 1.81E-01 122 838 "ADRA1B,ALCAM,GAS7,AQP6,CASK,ATP1B3,ATP2A2,NAE1,IL33,CALB1,CALM1,KALRN,CAST,KYAT1,CCK,RGN,CD86,CD38,COPB2,CHN2,LHX2,RAB28,PLAA,MYL6B,LY86,CNN3,CDC42BPB,RBM39,AKAP12,GDA,CTH,MYADM,MATR3,DAPK3,YTHDC1,DDX46,GRIN3A,NR1D2,DMTF1,FIS1,EDN1,EDN3,EDNRB,EGFR,EIF4G2,ERBB2,ACSL4,TUBB3,RACK1,FCGRT,FDFT1,FLNC,ANKFY1,ATP2C1,ALDH1L1,GFRA2,GHR,LYVE1,GLUL,GNAO1,GPD1,ATE1,GSTT2,GABARAPL2,HMGCR,IGF1,IL6R,JAK2,LAMP2,LIFR,LSS,MARK3,MAT2A,SHC3,PTOV1,TAGLN3,MXI1,NFE2L2,SLC11A2,PAX6,PDE4A,PDE4B,PGAM2,PIK3R1,MBOAT7,PPM1B,PPP3CA,PRKACB,PRKCB,PSMA6,PTK2,PEX2,OXR1,RNASE1,PCMTD2,SCN2B,SCP2,TRA2B,SH3GL3,ST6GAL1,SEC31A,SLC2A5,SLC8A1,KIF13A,KDM3A,SPTAN1,SSTR1,SS18,PHLDB1,PLCB1,MMS19,MLST8,AGTPBP1,DOCK9,PARD3,TNS1,TPM1,TTC3,ZFP37,MAP3K12,TUBA1A,DOCK8" Drug CID000003698 amrinone Stitch 2.36E-03 1.00E+00 1.63E-02 1.84E-01 12 43 "ADCY5,ADCY6,ADCY8,ADRB2,ALDH7A1,CACNA2D1,LRBA,CFL2,PDE3A,PDE4B,PDE4D,PRKACB" Drug CID000019688 norethisterone oenanthate Stitch 2.37E-03 1.00E+00 1.64E-02 1.85E-01 23 109 "ADORA1,ADORA2A,ADRB2,APBB2,APLP1,BCHE,CHN1,CNTNAP2,ENO2,BAIAP2,CYP46A1,GRIN2C,GRIN2D,MAPT,NBL1,NPTX1,RELN,PRIMA1,SNCA,PDZRN3,THRA,WNT7A,RTN4" Drug CID000108001 "3,5-dihydroxyphenylglycine" Stitch 2.39E-03 1.00E+00 1.65E-02 1.86E-01 15 60 "ATP2A2,CA4,CARS,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNK3,LIMS1,MAP4,MAPK3,PLD4" Drug 7422_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.39E-03 1.00E+00 1.65E-02 1.86E-01 34 182 "SEMA6A,BIN1,APBB2,SEMA4G,CDK13,BAG4,ENTPD4,PPP6R2,GIT2,TMCC2,DRP2,MBNL2,EIF5,VPS26C,ZNF589,FHL1,FAM49B,CAMKK2,SYT17,GRB10,RNFT2,SLC2A6,HMGCR,MBD1,MIA2,LYRM9,RIPOR1,SYBU,PLCB1,TRIM2,THRA,ZNF45,MAP3K12,GDPD5" Drug 7376_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.39E-03 1.00E+00 1.65E-02 1.86E-01 34 182 "CACNA1G,IL33,CALB2,ARHGAP22,WHRN,CREM,AKAP12,CTH,PITPNC1,DPH1,COQ7,FGFR1,DENND2A,ERAP1,GNAL,SHISAL1,KCNN1,MMP16,MYO7A,PDE4D,SMOX,PMP22,FA2H,PRPH,TMEM231,GSTCD,ASAP3,RBM34,CDK19,TBL1X,DNAH7,CABIN1,ZKSCAN5,DPF3" Drug 1160_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.39E-03 1.00E+00 1.65E-02 1.86E-01 34 182 "AP2A2,PDE8B,ATP6V0A1,CFLAR,ST3GAL5,SULT4A1,CREM,ZNF337,DBT,FAM13A,VPS13B,EPB41L2,ERBB2,GLYR1,TAGLN3,PDE4B,CCSER2,NECAB2,MBOAT7,PRKAB2,PRKACB,KLK6,FBXW7,RASA3,HSPA4L,PEX26,DNMBP,TBL1X,SLC44A1,TNS1,TPM1,KCNAB1,PCBP4,PHTF2" Drug 2688_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.39E-03 1.00E+00 1.65E-02 1.86E-01 34 182 "ATP2B2,AZGP1,CDO1,LHX2,NRG2,CREM,SIPA1L1,PDE4DIP,ZNF337,DGKG,HIPK3,MBNL2,AASS,ATP2C1,RASSF8,HNMT,IL6ST,NF1,PDE4B,PLCD1,MBOAT7,PRKACB,SUGCT,HSPA4L,CNKSR2,ZNF415,PEG10,PLCB1,SYN2,PCDHGA10,CHST8,ZBTB38,EVI5,FXR1" Drug 4376_DN Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.39E-03 1.00E+00 1.65E-02 1.86E-01 34 182 "SEMA6A,ALK,APC,PDE8B,SLIT2,AKAP12,PDE4DIP,DZIP3,DMPK,DLC1,RACK1,EVL,GHR,STON1,GPER1,GPR37,CNTRL,MEIS1,PIK3R1,PKIA,CEP97,CXXC4,LIMCH1,PHLDB1,TACC1,MCF2L,KIAA0930,TK2,CDK20,RUNDC3B,HIRA,FLRT2,EMSY,ITM2C" Drug ctd:D005047 Etoposide CTD 2.42E-03 1.00E+00 1.67E-02 1.88E-01 90 592 "ACADM,MTUS1,BIN1,APAF1,KCNAB2,APLP1,IGDCC4,ATP1A1,KIF1A,BID,BLM,CFLAR,ST3GAL5,DDR1,CAST,PRC1,ENTPD2,ZBED1,LHX2,ABCG2,COL9A3,TBPL1,CPS1,CREM,AKAP12,VCAN,CTH,DCAF4,HDAC4,DBN1,ZBTB24,HEPH,DMD,RCAN1,EDN1,EDNRB,EGFR,CERCAM,ERBB2,ERBB4,FDFT1,FHL1,FOXF2,FOXO3,FLNC,ATP13A4,CGREF1,FYN,MTHFD2,SESN1,PPARGC1A,DBF4,GPR37,STMN2,GSTT2,SLC2A6,STMN1,MATN2,MBP,MXI1,MYCN,MYT1,NFE2L2,IGSF11,OGG1,P2RX7,PDE4B,ABCB1,GPSM2,PMP22,MAPK3,ROBO1,RXRA,MAPK12,MRAS,LIMCH1,RBM34,SPP1,COBL,ANKRD28,TBL1X,TRIM2,TP53BP1,WRN,XRCC4,ZNF32,ZNF45,CIAPIN1,PCBP4,ST7" Drug 2911_DN Naftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "BRAP,APBB2,ZBTB10,SLC16A4,SOCS6,HOMER3,IQCK,C2CD2,HDAC9,DTNA,PCOLCE2,FECH,CAMKK2,ATP2C1,ADAM28,LILRA2,MAP4K5,KCNN2,KPNA5,SETD4,OPA1,STRN3,LRP12,C1orf109,HSPA4L,PPM1E,FBXO11,NUBPL,DHX30,TROVE2,JMJD6,TCF4,TMPO,FTSJ1,EPM2A" Drug CID000003016 diazepam Stitch 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ALDH7A1,BBS2,BCHE,CACNA2D1,CBR1,CCK,DBI,GPHN,STX2,ZMYND10,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GPT2,GRIK4,GRIK5,GRIN2C,GRIN2D,NPY,NPTX1,NPTX2,OPRL1,PTCH1,AP1AR,SLC4A3,ARHGEF9,ZEB1,SMUG1" Drug 1832_DN Isoflupredone acetate [338-98-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "ABHD6,MTUS1,ADGRF5,APOC1,SYNJ2,CSF1,CSNK1E,DAPK3,LYPD1,COQ7,SCML2,SEMA4D,CGREF1,FYN,INPP5K,USP19,HTATSF1,FERMT2,GPER1,ICA1,KIFC3,MITF,ZNF862,NEK1,PDE4B,GRAMD1C,CNTLN,GAL3ST4,RGS4,FNBP1,VPS13A,DNMBP,ZEB1,NAV3,URM1" Drug 5254_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "APC,ARRB1,ADAM15,SYNJ1,RAB28,DAPK3,DBN1,NR1D2,RCAN1,FCF1,MBNL2,ING4,EPB41L2,RRAGB,FGF13,FGFR1,IQCG,PDLIM5,STON1,RASSF8,MBP,KITLG,PLEC,FAM184A,KDM4C,ZC3H13,STX1A,PLCB1,PCDHA5,TMPO,ZBTB14,MPPE1,EPM2A,PHTF2,SENP7" Drug 3690_DN 0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "ABR,ACTN1,MTUS1,PKP4,HAP1,LARGE1,PLAA,HOMER3,DZIP3,DMPK,RRAGB,FGF1,PDLIM5,GLYR1,ELOVL5,AGFG1,MBNL1,PIK3R1,PLEC,PTN,TCP11L1,DZIP1,BTBD7,PEG10,CDK19,SS18,TCF4,TRIM2,TIMP4,TRIO,LAT2,XRCC4,NAV3,MPPE1,UBE3B" Drug 4400_DN Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "NDRG2,ALK,GAS7,LDLRAD4,CAMK2B,ARHGEF2,FOXN3,RAB28,AKAP7,ABI3BP,SPOCK2,DTNA,ERCC2,KHDRBS3,TMEM8B,GNG4,ICA1,KCNN1,KIT,MBD1,MSI1,NF1,NFYA,NTRK2,RETREG1,PRKAR1B,EMID1,BTBD7,SMARCD3,LIMCH1,KDM4B,CLSTN2,ZEB1,R3HDM1,HIRA" Drug 1622_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; HL60; HG-U133A Broad Institute CMAP Up 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "NDRG2,AMT,MAP4K3,ARNTL,ARRB2,BACH1,CD86,CHN2,RAB28,CREM,RNF14,PPP1R16B,ZNF337,FAM13A,EGR3,IRAK4,ENO2,SMC2,OGA,MALT1,HMGCR,MAP4,NFE2L2,SMOX,MAPK3,CNNM2,PTX3,RNASEL,SAFB,SGK1,SLC2A5,SLC6A8,ARHGEF40,GLT8D1,TSPYL2" Drug 1646_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "CFLAR,CA4,HAP1,FOXN3,SH2B1,CSNK1E,CTH,TBC1D5,SPOCK2,DPH1,DTNA,ING4,ANKMY1,ZNF589,FGFR1,IQCG,INPP5K,MSL3,POLL,GPER1,PADI2,ICA1,KITLG,NEK1,NFYA,PPP5C,NEK11,CEP68,PLCB1,TBL1X,ZNF34,CABIN1,UBE2H,EMSY,MARCH8" Drug 4304_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "RALGAPA1,CDC42BPA,CFLAR,SPAG9,SRSF11,HOMER3,FCF1,STX2,VPS26C,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,AGFG1,SCIN,IL6ST,MAP4,MMP16,MYO6,NFIX,PDE4D,STRN3,SLC25A36,SEC14L1,FBXO11,ZNF667,TBL1X,TCF4,ZEB1,DICER1,TMPO,R3HDM1,EVI5,KAT6A" Drug 7438_UP Isotretinoin [4759-48-2]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.42E-03 1.00E+00 1.67E-02 1.88E-01 35 189 "ABHD6,AK2,ALCAM,BIN1,APBB2,APC,CFLAR,MTMR2,CA12,CREM,ENTPD4,CSF1R,ACSL4,B4GALNT1,SEPT9,GLYR1,RASSF8,LMO2,MBP,SETD4,PFKFB3,KLK6,CNNM2,RIPOR1,RNASEL,NCBP3,SYBU,SLC22A4,SMARCD3,SNAP25,PLCB1,TRIM2,CDK20,VLDLR,MPPE1" Drug CID000005300 NSC236997 Stitch 2.44E-03 1.00E+00 1.67E-02 1.88E-01 83 539 "ABR,ADCY5,ADCY6,ADCY8,ADRB2,AGT,ZNF687,OGT,APOC1,APOC2,AQP6,SLC2A11,ALDH7A1,BBS2,CALM1,CAPN3,CBS,CCK,RGN,CD86,COL4A5,CS,VCAN,MYEF2,LYPD1,EBF1,EDN1,EDN3,EDNRA,EDNRB,EGFR,CD320,KAT8,FOXO3,OGA,GAA,GAD1,GATM,GCK,MSTN,USP19,GHR,PPARGC1A,GPD1,GPD2,CIT,HBA1,CPT1C,AGFG1,IRF8,MYLK2,IGF1,SFXN5,MBP,MITF,MMP16,MMP17,NPY,P2RX7,GPR85,PFKFB2,PFKFB3,PFKFB4,PKM,PPARA,PRKCB,MAPK9,PTPRN,PTPRO,GSTCD,S100B,FNDC3A,SLC14A1,SPP1,PEG10,PBLD,SST,APOM,ZEB1,SIRT1,THRA,XRCC4,NETO1" Drug 7029_DN Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "BRAP,CDC42BPA,BCAS1,PPFIA3,KIF1A,CFLAR,CAMK2G,ENTPD6,SOCS6,MAP4K4,HOMER3,CTH,TBC1D5,DBN1,ANKMY1,ATP2C1,BTN2A1,RNFT2,KHK,MAP4,MIA2,TMEM104,RGS3,RNASEL,SUPT20H,ABLIM3,EPN2,BTBD7,IQSEC2,PDLIM2,SATB2,BEX4,VGF,LMF1,MAP3K12,HPS4" Drug 2950_UP Roxarsone [121-19-7]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRA1D,AMPH,PKP4,KIF1A,HIP1R,SCARB1,MAGI1,HOMER3,CNTN1,DZIP3,DBT,DCTN1,KLHL3,CDON,RASGRP2,FHL1,KCNMB4,ATXN2L,HNMT,GIT1,TCP11L1,RASA3,ST6GAL1,SNCA,TMCC1,SPTAN1,SPTB,JMJD6,PDLIM2,SZT2,CHST8,ZNF34,TRPS1,KCNE5,LMF1,GDPD5" Drug 4196_DN Benperidol [2062-84-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "PPFIA3,ARRB2,CFLAR,CCNT1,LHX2,NRXN3,RGS6,VCAN,SPOCK3,EXOG,DTNA,MBNL2,MTSS1L,ST3GAL6,SEPT9,LPAR4,GRM8,SCIN,MAP4,MAPT,NF1,BCAS3,PTPRB,FBXW7,SBF1,ATXN7,FAM214B,KANSL3,ASTN2,THRA,TIAM1,TIMP4,TK2,VIPR2,KCNAB1,MPPE1" Drug 5795_DN Demecarium bromide [56-94-0]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "EP400,PDE8B,NRXN3,CSF1,VCAN,EDNRA,HIPK3,ANKMY1,IQCG,ANKFY1,CINP,B4GALNT1,ERAP1,USP19,HNMT,ICA1,MATN3,GIT1,NF1,PIK3R1,NLE1,BEND5,FBXW7,ASAP3,PEX26,ELMO2,ZKSCAN3,SPTAN1,CAMTA2,SYT1,COBL,WSCD1,SZT2,HIRA,EMSY,HPS4" Drug 1178_DN fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,ADORA2A,AP2A2,C1QTNF3,APC,MARK4,FOXN3,ARMC8,SEC31B,C2CD2,SPATA2,ENO2,ZNF589,FGFR1,CAMKK2,CACFD1,MAP4K5,SLC11A2,SETD4,PFKFB3,KCTD15,PLCB2,MBOAT7,SAMD9,TMEM104,PTCH1,GTDC1,DZIP1,ARFGAP1,COA1,TCF4,NSD1,ZMAT3,GORASP1,XRCC4,ZNF142" Drug 3726_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AP2A2,ALK,APOC1,CDK10,C5,CACNA2D2,PICK1,PARD6A,DMPK,DTNA,CELSR3,EIF4G2,ING4,MRNIP,EZH1,SCML2,FGFR1,CACFD1,KPNA5,TM6SF1,MT1M,TAGLN3,NELL2,NF1,NPR2,PDE4B,PTCH1,ZCWPW1,RGS4,ZNF821,ZHX3,TIAM1,VGF,VIPR2,NT5M,TIGD6" Drug 3055_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,LTBP4,ALK,CDK10,RGS9,BMP7,FUBP1,CACNA2D1,USP2,AKAP6,COL9A3,ARHGEF10,PPP1R16B,USP6NL,APC2,KAT8,BAIAP2,PRELID3A,RUNDC3A,PCLO,GUCY1A1,NPY,PDE1C,BCAS3,PTPN13,BEND5,CLIP1,SCN8A,ASAP3,SPTB,NFASC,TACR1,TK2,KLC2,MAP3K12,GDPD5" Drug 3909_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ACADM,APLP1,ARRB1,CFLAR,SYNJ2,CAMK2G,USP6NL,LYPD1,DMPK,EGR3,PLXNC1,HSD17B14,FAM49B,GCNT2,SRCAP,GLYR1,RAB30,ICA1,ITPKB,MAP2,MPP2,RETREG1,PRKAR1B,RASA3,LIMCH1,NXT2,STX1A,PLCB1,KIAA1107,TNS2,SLC44A1,HEY1,PARD3,GDPD5,PCBP4,PHTF2" Drug 2047_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ABR,BIN1,EP400,CDK13,BACH1,SCAPER,CACNA1I,MYRF,STOML1,HOMER3,LYPD1,HIPK3,IRAK4,DENND4A,FER,TRMO,CINP,TMEM8B,GLYR1,MSL3,GNAL,CACFD1,KIFC3,GIT1,NEK1,FAM184A,ZFP30,KDM4C,IQSEC2,CDK19,TBL1X,TCF4,TRIM2,WIPF1,SPHK2,KCNAB1" Drug 2312_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADD1,SEMA7A,APBB2,FAM131A,APOC1,NCOA1,SLC4A4,RIPK1,CFLAR,CRY2,DCAF8,TXNL4A,COPS8,POLL,GSTM5,HNMT,ZNF862,CNOT4,SLC25A23,LRP12,MINDY2,RIPOR1,GTDC1,FNDC3A,TTC17,TSPYL2,TROVE2,ANKRD12,PCDHA6,TK2,ZKSCAN5,PLPPR2,VGF,ZBTB14,EPM2A,UBE3B" Drug 2352_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,AMT,KCNAB2,MARK4,CAMK2B,CAMK2G,SLC25A14,HIP1R,TAOK2,IQCK,ARHGEF10,DAPK3,KIAA0753,COQ7,ST3GAL6,TRMO,PDLIM5,NEU3,GRB10,ITGAM,MAPT,MPP2,CNNM2,RET,PLPPR3,MRAS,BTBD7,ZKSCAN3,SNAP25,DOK5,ZC4H2,EXOC7,PDLIM2,CRTC1,TPM2,HIRA" Drug 1151_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,ARNTL,PDE8B,MTMR3,CAPN3,KYAT1,SLC16A4,PICK1,MAGED1,CREM,SIPA1L1,DAPK1,KIAA0753,RUSC2,DTNA,RASGRP2,TRMO,ERAP1,USP19,LAMA2,NINJ2,P2RX7,PILRA,POLG,GALNT10,PPP4R3A,SNCA,ZC3H13,ZBTB43,EXOC7,SZT2,GPR161,FLRT2,VIPR2,ST7,PHTF2" Drug 4718_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,NDRG2,CDK13,CFLAR,CACNA1I,QKI,CRMP1,CSF1,GREB1,EXOG,EDN1,ING4,RASGRP2,NCALD,RRAGB,FGFR3,SRCAP,GLYR1,IL6ST,KITLG,NEK1,CDK18,NLE1,STRN3,PPP5C,GSTCD,ZKSCAN3,OGDHL,LIMCH1,PCDHGA10,PCDHA6,ZNF34,HEY1,LAT2,ZNF24,SEMA3B" Drug 4538_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,CDC14B,NRXN3,CREM,CNTNAP2,HDAC9,ZFYVE16,ARMCX2,SUGP2,FGFR1,BAIAP2,TRMO,GAD1,TMEM8B,DISC1,STON1,IFI16,TJAP1,SMIM7,ZSCAN32,FAT4,ROGDI,SUGCT,FBXW7,LIMS2,KBTBD4,IFT122,THSD1,CEP68,IQCE,SZT2,TFIP11,NT5M,MPPE1,SMIM8,TIGD6" Drug 3933_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "APLP1,RUNX1T1,SEPT7,CRLF1,PICK1,SNCAIP,CSF1,DCAF4,MTSS1L,ERCC2,REEP2,FYN,SIGLEC8,IFI16,ITGA7,KHK,L1CAM,TAGLN3,NPR2,NTRK2,TREM2,PLCB2,PTPRB,GAL3ST4,RFX2,KLHL11,ARHGAP26,SMG6,DOCK9,DNAH7,TNS1,CLIP2,XRCC4,MKRN3,SLC30A3,SLC17A7" Drug 2339_UP Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,MARK4,BMP7,SULT4A1,CREM,CSF1,VCAN,SLITRK5,PPP1R16B,RCAN1,DLC1,PDLIM5,INPP5K,LSS,AFF1,NF1,P2RY1,PFKFB3,SLC25A23,FAM184A,PLPPR3,FNDC3A,SNCA,TMCC1,KDM4B,ZBTB43,ATP10B,CLSTN2,STXBP1,DNMBP,TBL1X,SIN3B,CRTC1,TK2,CDK20,UBE3B" Drug 3847_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "LTBP4,TRMT9B,SEMA4G,MTMR3,CACNA1I,CAST,CHN2,PICK1,CNTFR,CNTN1,NRG2,DAPK3,HS3ST2,DTNA,PTK2B,DLC1,AGAP2,SRCAP,GLYR1,GPER1,ATXN2L,HSF2,IRF8,LSS,NF1,CLDN11,PFKFB2,PRKAR1B,RGS12,SEC14L1,KIF13A,TSNAXIP1,TBCEL,PIK3R5,KCNAB1,JPH3" Drug 2019_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,CDK10,ST3GAL5,RUNX1T1,SEPT7,CLTB,AKAP7,ARHGEF10,SOCS5,NR1D2,ERCC2,FGF1,ATP2C1,GALC,RUNDC3A,TXNL4A,IRAK3,MAN1B1,MPP2,NTRK3,OCRL,PDE1C,SBF1,ZNF821,SH3BP2,PPP4R3A,ELMO2,BTBD7,RCOR3,SNAP25,THRA,TNS1,TSN,LAMP5,TFIP11,ST7" Drug 4965_DN Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AK2,SRPX,AMT,ARHGEF7,SCAPER,KYAT1,MAGI1,PLEKHB1,AKAP7,LRIG1,SOCS5,DZIP3,ARHGEF4,JAKMIP2,MED12,BAIAP2,OGA,CRCP,CACFD1,INPP5B,MPP2,ZNF862,NPTX1,WDR25,RIPOR1,FAM184A,DCUN1D2,SUPT20H,PEX26,ZHX3,KDM4C,TK2,TPM1,TRIO,VLDLR,EVI5" Drug 7277_DN Azapropazone [13539-59-8]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NCOA1,ATP2A2,AP4M1,RCBTB2,QKI,CSNK1E,PARD6A,SGSM2,OPTN,RRAGB,SCARA3,IQCG,ANKFY1,EFCAB2,INPP5K,GLYR1,LPAR4,SLC2A6,MBD1,ZNF862,ZDHHC14,SUPT20H,ASAP3,COA1,ZBTB43,PHLDB1,ARHGEF9,EXOC7,TIAM1,TNS1,ZKSCAN5,FAM155A,OSBP2,UPF3A,EVI5,ACTR3B" Drug 6808_UP Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ACTN1,ADORA1,AGT,AMH,AMPD3,BIN1,OGT,EP400,CALB1,ARHGAP33,CPS1,GREB1,DTNA,EGR3,DENND4A,ACSL4,KCNQ3,CLDN11,SMOX,C19orf57,MAPK10,RET,GTDC1,SBF1,FBXO11,SMARCD3,KDM4B,R3HDM1,TPM2,FAM155A,LMF1,SPHK2,SLC17A7,KAT6A,SMIM8,SENP7" Drug 2306_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADCY6,APBA2,ARSE,DNAH17,CFLAR,GYG2,CALB2,CAST,CDO1,AKAP6,HEYL,ELN,RCAN2,SPEG,FGF14,FHL1,TPK1,NEU3,IL6ST,KIF5A,KPNA5,MID1,ADAM22,PTCH1,RGS12,ZFHX4,SALL1,SLC14A1,SP4,ZBTB43,SPART,GPR161,RUNDC3B,OSBP2,VIPR2,SLC30A3" Drug 2266_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "BIN1,APBA2,KCNAB2,ARRB2,GYG2,KRIT1,RCBTB2,AKAP7,CSNK1E,EDNRA,ZNF589,ANKFY1,FAM49B,SRCAP,MALT1,GNG4,GSN,KCNH2,MBD1,MSI1,NPTX1,SLC11A2,PRODH,PTCH1,ZSCAN32,RPS6KA2,SBF1,ZNF821,TRA2B,PREX2,PEX26,CLSTN2,AP4E1,TK2,HIRA,XRCC4" Drug 4587_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "PKP4,SLC4A4,ALDH7A1,CFAP410,CACNA1A,PLEKHB1,AASS,MRNIP,STX2,SPEG,ETV1,EZH1,FGFR1,CINP,OGA,USP19,MSL3,HNMT,INPP5B,MAPT,MN1,MT1M,SLC11A2,PLXNB1,PRPH,CSRNP3,ASAP3,FAM214B,ZNF334,CRTC1,TPM2,OSBP2,VIPR2,XRCC4,MAP3K12,NT5M" Drug 2103_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADD1,APC,CDC14B,FOXN3,HOMER3,PARD6A,SUGP2,COQ7,SPEG,ZNF589,FGF1,FGFR1,SRCAP,GPD2,CLASRP,SHISAL1,INPP5B,JAK2,MAP4,MPP2,ZNF862,LRP12,SAMD9,RIPOR1,FAM184A,ZDHHC14,RGS4,CAMTA2,SS18,EXOC7,PDLIM2,ZEB1,SZT2,CABIN1,ZNF45,ZNF189" Drug 4739_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "GAS7,CDC14B,MTMR3,CAMK2G,ARHGAP33,TAOK2,LHX2,FAM189A2,WHRN,GREB1,DNM1,DLC1,ST3GAL6,FGFR1,FHL1,IQCG,SEMA4D,POLL,GRM8,ATXN2L,MPP2,NF1,NPTX1,P2RY1,LRP12,SAMD9,CEP97,GTDC1,FBXW7,SH3BP2,ZHX3,STX1A,DICER1,CDK20,HIRA,PLPPR2" Drug 6401_UP F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "FZD9,LTBP4,APBA2,APC,GAS7,PPP4R4,ATP6V0A1,KSR1,CBS,MFAP3L,CHRDL1,EDN1,CDKL3,PDLIM5,FUT9,NEU3,CACFD1,KCNJ5,MAPT,MPP2,PFKFB2,LRP12,PPP5C,CEP41,PTPRE,KCTD17,ATXN7,SH3BP2,ASAP3,SLC6A11,DOK5,DDN,TBCEL,TIAM1,R3HDM1,KCNAB1" Drug 1495_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "C1QTNF1,CDC42BPA,APBB2,APC,BCAS1,ARHGDIG,CFLAR,ST3GAL5,SLC16A4,ARHGAP33,HOMER3,ARMC8,AKAP5,DAPK3,SPOCK3,PHF20L1,TNK2,DLC1,OGA,B4GALNT1,MBD1,NELL2,NNAT,PLCD1,PRODH,TRIM68,PPP4R3A,PKNOX2,SPTB,SPART,CHST8,ZKSCAN5,SPHK2,UBE3B,RNF170,SENP7" Drug 4468_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "KIF1A,BACH1,RAB28,SPOCK3,CDON,DTNB,EDN1,EBI3,EPHB1,REEP2,FYB1,RAB30,PRUNE2,NXPH3,ICA1,LIFR,MMP16,MX1,NTRK3,MTRF1L,PPP2R2B,CEP41,SAMD9,PTPRH,PTPRN2,TCP11L1,SEMA6D,SLC6A11,SLC11A1,ARHGAP26,SZT2,DOCK9,SLC44A1,TK2,ICAM5,SLC17A7" Drug 2936_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,ANK2,PPFIA4,MARK4,MTMR2,CBS,SOCS6,HOMER3,AKAP7,CRY2,PDE4DIP,SLITRK5,DZIP3,SPATA2,CD320,TRMO,POMT1,ERAP1,DISC1,SRCAP,USP19,PADI2,ATXN2L,AGFG1,IDH3A,MEF2C,MIA2,NF1,CNOT4,PDE4B,SBF1,NUBPL,ARHGEF40,EXOC7,OBSL1,AP4E1" Drug 4655_DN Enoxacin [74011-58-8]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "C1QTNF1,CBFA2T2,LHX2,RAB28,QKI,CREM,DTNA,FCF1,ING4,ERCC2,ZNF589,FGFR1,CINP,HSF2,IFI16,SHISAL1,JAK2,KPNA5,LIG4,ADAM22,PFKFB2,PLCD1,POLG,TMEM231,PID1,ZCWPW1,TRAPPC13,SAFB,ZNF821,FUZ,PPP4R3A,MYH15,TMCC1,NXT2,ARHGEF9,CRTC1" Drug 6474_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ABHD6,SEMA6A,BEGAIN,SGCE,RUNX1T1,CLGN,CRMP1,PDE4DIP,PHF14,SPOCK2,EGR3,TPK1,GALC,ALDH1L1,SRCAP,ICA1,ITGAM,LIG4,MAPT,MBD1,NF1,CNOT4,CDK18,LRRN3,CEP97,CLIP1,PPP4R3A,ZSWIM8,ATP10B,TRIM2,PCDHA6,WIPF1,LAT2,XRCC4,ADAMTSL3,DPF3" Drug 2010_UP Erythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,ADORA1,CDC42BPA,NRP2,SCAPER,CACNA1I,CAPN3,ARHGAP33,C2CD2,SOCS5,TOM1,STX2,ATP2C1,INPP5K,DBF4,MSL3,ITPKB,KCNJ5,LSS,MITF,NELL2,PDE4D,SLC25A23,SMIM7,PPP2R2B,ZC3H13,SPART,ZC4H2,TK2,UBTF,TBC1D15,WRN,ZNF23,ZNF142,REEP1,ACTR3B" Drug 414_UP "estradiol, USP; Up 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "APOC1,ARRB1,MTMR3,RUNX1T1,DLGAP1,CHRNA4,SH2B1,AATK,DTNA,SUGP2,NRN1,OLFM1,STAU2,GNAO1,BTN2A1,ADAMTS6,ICA1,IL6R,MARK1,MYO7A,NPR2,OPRL1,CCSER2,POLG,CEP41,PRKCB,RET,SLC9A5,KBTBD4,CDK5RAP2,KDM4B,ZBTB43,ZNF34,CDH22,ZNF184,ST7" Drug 2795_DN Palmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "C1QTNF3,APBB2,GAS7,BCAS1,SYNJ1,SYNJ2,ARHGEF2,PLEKHB1,FAM189A2,HOMER3,CSF1,PPP6R2,MFAP3L,EZH1,INPP5K,AHDC1,HNMT,KCNH2,LMO2,ZNF862,NF1,RETREG1,LRP12,MBOAT7,WDR25,RIPOR1,ZCWPW1,SH3BP2,ABLIM3,ERC1,MCF2L,CRTC1,KCNK12,SPHK2,GDPD5,SENP7" Drug 1403_DN Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; HL60; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,MARK4,CAMK2B,CAST,ARMC8,SPOCK2,DNM1,ING4,EZH1,FAM49B,SEPT9,DBF4,GRIK5,ACOT7,AGFG1,MAP4,MBD1,NEK1,SETD4,CLDN11,PLCB2,SMOX,RETREG2,RAD51D,RBBP6,DPF2,MRPS18A,MAPK12,FBXO11,ELMO2,STXBP1,NSFL1C,ANKRD12,MCF2L,TST,PHTF2" Drug 1996_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; HL60; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,OGT,NUMB,ST3GAL5,PTBP2,CD38,TAOK2,QKI,TMEM184B,HDAC9,DTNA,SMC2,OGA,LILRA2,CACFD1,BTN2A1,GSTM5,MAN2A2,GIT1,NF1,SETD4,PLCB2,LRP12,PPP2R2B,NEK11,SLC2A5,PEX26,SIRT2,ZKSCAN3,SS18,MPRIP,NSFL1C,ZEB1,KAT6B,CHST5,TFIP11" Drug 4676_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,CDC14B,ATP1A3,SYNJ1,SCAPER,LDLRAD4,NRXN3,ARMC8,SLC4A8,ARHGEF10,PDE4DIP,CNTNAP2,CNNM1,HSD17B14,LPAR4,GUCY1B1,IFI16,ADAM22,NEK1,NF1,PRKAR1B,PTPRB,TMEM231,KHDRBS2,ZNF671,ANKRD6,CCDC88A,TSNAXIP1,SOX15,IZUMO4,UNC5B,IQSEC2,PLCB1,KIAA1107,TK2,RUNDC3B" Drug 874_DN (-)-depudecin; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CLK4,NDRG3,BRAP,OSBPL1A,BIN1,PKP4,CDK10,QKI,CSNK1E,USP6NL,GIT2,DMTF1,FCF1,MRNIP,FGFR3,NOP56,FAM49B,INPP5K,ZNF276,MSL3,NEK1,NFYA,CNOT4,CCSER2,RETREG1,NLE1,STRN3,ING3,ROBO1,MCMBP,ZNF430,ZHX3,ZBTB43,SS18,KAT6B,GAN" Drug 3690_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "APC,SLC2A11,BMP7,RAB26,HAPLN1,LRIG1,EDN1,EGFR,ING4,SEMA4D,FLT1,FAM49B,SIGLEC8,GNAL,KCNN1,KIFC3,LSS,LYRM9,PALM,CDK18,PDE4B,PGAM2,SMOX,PNMA3,C19orf57,LRRN3,PTCH1,SUGCT,SOX15,HECW1,MCF2L,DMXL2,ZFPM2,PIK3R5,VIPR2,SLC17A7" Drug 4742_DN Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG3,NDRG2,LTBP4,BIN1,APBA2,GAS7,CDC14B,MARK4,ST3GAL5,WHRN,CSNK1E,CNTNAP2,DCAF8,MRNIP,HSD17B14,ST3GAL6,AFF2,ALDH1L1,ATXN2L,MAP4,MSI1,ADAM22,ZNF862,RETREG1,NLE1,PRKAR1B,ZFHX4,PEX26,SNCA,UNC5B,ZNF423,SMG6,SZT2,PCDHA5,HIRA,NDRG4" Drug 2119_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "PPFIA3,ARRB2,CAMK2G,SPAG9,HOMER3,WHRN,CPS1,CSNK1E,TM9SF4,TBC1D5,DBT,SUGP2,TNK2,FAM49B,DENND2A,PRRC2B,RNFT2,IFI16,IL6ST,L1CAM,MX1,CCSER2,AP1AR,ATXN7,SUPT20H,ASAP3,ZNF430,ZKSCAN3,CDK5RAP2,KDM4C,SS18,EXOC7,KIAA0930,CABIN1,HIRA,MPPE1" Drug 6273_DN Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,BACH1,SCARB1,SRSF11,RAB28,PLAA,COL4A5,DBT,PHF20L1,PCOLCE2,EZH1,PRKAG2,PDLIM5,INPP5K,RNFT2,HSF2,ICA1,MAP4,MBD1,LYRM9,NEK1,NFYA,OGG1,PPP3CC,PRKAB2,PDZRN3,TSPYL2,ELOVL4,NSFL1C,ANKRD12,MCF2L,DNMBP,TRIM2,XRCC4,MPPE1,PHTF2" Drug 6582_DN AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "APBA2,ADGRB2,SYNJ2,WASF1,CDH2,B4GALT6,CNTN1,VCAN,SOCS5,ACSL4,ST3GAL6,ZNF589,FYN,USP19,CACFD1,MAP4K5,ACOT7,MBNL1,MYO6,CDK18,PDE1C,PLEC,FSD1,PTCH1,FAT4,RGS4,SBF1,ZNF821,SUPT20H,TNS1,TRIO,CLDND1,ZNF74,FZD3,ST7,UBE3B" Drug 7408_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ABHD6,ADCY6,APBB2,PPFIA3,MPDZ,ARHGEF7,SCAPER,CA4,SOCS6,LRIG1,FAM169A,DZIP3,MFAP3L,PHF20L1,EGFR,EGR3,COQ7,F8,GRB10,INPP5B,MATK,MBD1,ADAM22,CNOT4,PLTP,MBOAT7,RET,CCDC88A,SMARCC2,TMCC1,TSNAXIP1,CLASP2,PLCB1,MTCL1,TIAM1,VLDLR" Drug 2571_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,MTUS1,DOC2A,CDC14B,ARRB1,PDE8B,N4BP2L1,CACNA1A,CHN2,CPS1,CREM,MRNIP,ELN,DLC1,SPACA9,MEF2C,AFDN,N6AMT1,NPR2,ENPP2,CCSER2,PPARA,SEC14L1,ZNF821,CNKSR2,EPN2,IZUMO4,DDN,SS18,NSD1,CRTC1,SLC44A1,TLR4,CDK20,LMF1,PLSCR4" Drug 2528_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "RALGAPA1,NDRG2,AGT,PLA2G4C,PDE8B,AZGP1,PROM1,LDLRAD4,B4GALT6,SLC4A8,DGKG,DAPK3,HEPH,MFAP3L,CNNM1,TNK2,EIF1,APC2,INPP5K,PCDH17,RUNDC3A,GNAO1,GNG4,NCKAP1L,NPTX1,CCSER2,PPP5C,ZSCAN2,RGS12,RNASE1,EPN2,LIMS2,SPTB,CLSTN2,CRTC1,TIAM1" Drug 2240_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "SYN3,AP2A2,AMPH,APC,GAS7,PRX,CDK13,CFLAR,NRG2,DMPK,EDNRA,MTSS1L,ANKMY1,PCLO,NELL2,NF1,NNAT,NOVA2,PLCB2,MINDY2,MAPK7,PRODH,SAMD9,ZMAT4,SCN8A,SH3BP2,SH3GL3,ST6GAL1,SLC2A5,MAPKBP1,CDK19,PCDHA5,R3HDM1,UGT8,CLIP2,NT5M" Drug 3269_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AP2A2,GAS7,FAM131A,APOC1,SLC4A4,MTMR2,CACNA2D2,FAM189A2,VAX2,QKI,SH2B1,CSF1R,IRAK4,FER,FHL1,OGA,SRCAP,FERMT2,TDRKH,SPACA9,GSN,HNMT,LIG4,MAP4,MPP2,ADAM22,LYRM9,SLC11A2,NLE1,SLC25A23,PRKAR1B,EMID1,TTC17,KDM4B,IQSEC2,TBL1X" Drug 2035_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,C1QTNF1,BIN1,CDC42BPA,APAF1,SEMA4G,ARNTL,MARK4,ST3GAL5,RAB29,CAST,CRMP1,DOCK4,FAM13A,ZMYND10,FGFR1,ARFIP1,TXNL4A,SLC2A6,PADI2,KHK,SCAMP5,NEK1,CLDN11,RETREG1,TMEM104,ROGDI,SATB1,ZSWIM8,CEP68,RGL1,STXBP1,TSN,ZNF45,REEP1,ITM2C" Drug 3850_DN Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AMH,APAF1,GAS7,CDK10,NCOA1,SYNJ1,BAIAP3,TAOK2,ENTPD4,DCAF4,DUSP9,ELN,SCML2,TPK1,SRCAP,GFER,PCDH17,PCLO,CACFD1,HNMT,ITPKB,RETREG1,STRN3,MAPK7,SNRK,ZSCAN2,ZDHHC14,ZMAT4,EMID1,SBF1,FAM214B,DMXL2,KIAA0930,LAT2,EMSY,KCNAB1" Drug 6169_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,FGD2,SLC4A4,MTMR3,RHBDL1,SLC16A4,CBFA2T2,ASIC3,FAM189A2,KLHL3,OPTN,TNK2,SRPK3,VPS13B,F5,CHST15,OLFM1,CPLX2,PCDH17,LYVE1,GPR75,KCNB1,KCNJ5,ADAM22,MYCN,NPTX1,PCDHGC3,PDE4D,RETREG1,TMEM231,SLC11A1,KDM4B,ASTN2,PHF24,FAM189A1,VSNL1" Drug 2719_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRA1D,SRPX,CDC42BPA,APOC1,PPP4R4,NUMB,LDLRAD4,CACNA1A,EPS15L1,AKAP7,CSNK1G3,USP6NL,DTNA,SUGP2,IGSF6,F5,ST3GAL6,PCYOX1,IQCG,ZNF44,ERAP1,SEPT9,GPR75,GNG4,IL6ST,MAP4,NPR2,PCDH9,POU6F1,PTK2,SEC14L1,SLC11A1,ADGRL3,KIAA1107,PLPPR2,CLIP2" Drug 5680_DN Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "EPB41L5,APOC1,NCOA1,EIF4G3,QKI,AKAP7,BAG4,SIPA1L1,PDE4DIP,FAM169A,DCAF8,MFAP3L,MED12,DTNA,MRNIP,TXNL4A,POLL,CNTRL,MMP16,ADAM22,PTCH1,RAD51D,ZCWPW1,RGS3,RPS6KA2,SEC14L1,PPP4R3A,FAM214B,SLC22A4,ZHX3,SPTAN1,DIP2A,SLC44A1,NDRG4,EVI5,PDSS2" Drug 2668_UP "estradiol, USP; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,SYNJ1,CFAP410,SLC16A4,STOML1,QKI,CREM,SIPA1L1,VCAN,DCAF4,ZNF337,DGKG,DBT,SPOCK3,HIPK3,VPS13B,FGFR1,FHL1,GATM,LILRA2,GSN,ATXN2L,KHK,KIT,NINJ2,OXTR,PDE4D,PFKFB2,ABCB1,PPP2R2B,CNNM2,PTCH1,SLC11A1,SMARCD3,ZNF34,TRPS1" Drug 2037_UP Lynestrenol [52-76-6]; Up 200; 14uM; HL60; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,APBB2,RASL11B,ADAM15,BMP7,MTMR3,CAST,RUNX1T1,ABCG2,CRY2,AATK,CTH,C2CD2L,NR1D2,TOM1,PLXNC1,ING4,RASGRP2,TRMO,CELF1,GPR12,HNMT,NF1,PPP2R2B,SH3BP2,FAM102A,SLC2A5,KBTBD4,ELMO2,ZC3H13,SPTB,LMO3,ST5,TBL1X,CA14,MAP3K12" Drug 2482_DN Tolazamide [1156-19-0]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,ADAM15,LDLRAD4,HIP1R,SCARB1,CLCN3,STOML1,ARMC8,RUBCN,DBT,RHOBTB1,NR1D2,HIPK3,EIF1,PTK2B,PDLIM5,GALC,TJAP1,NF1,NFYA,PLCD1,PLEC,CNNM2,RNASEL,C12orf49,GSTCD,ZNF821,RASA3,BTBD7,ARFGAP1,EXOC7,UBTF,MAP3K12,UBE3B,ACTR3B,NLRP3" Drug 2697_DN fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,DOC2A,MPDZ,CACNA1G,RCHY1,CREM,CSF1,PPP1R16B,ARHGAP32,TBC1D5,CNNM1,FAM13A,PLXNC1,ING4,PTK2B,TRAF3IP2,AHDC1,ZNF276,ITGAM,MAPT,MEF2C,MYO6,NFYA,NPR2,PDE4A,PMP22,RXRA,AMBRA1,IZUMO4,LHPP,PLCB1,TCF4,TNS1,SMUG1,CLIP2,SPHK2" Drug 5070_DN Prenylamine lactate [69-43-2]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADCY6,NME5,PPFIA3,LGR5,CAMK2G,CBFA2T2,HAPLN1,VCAN,EDIL3,FAM13A,BAIAP2,B4GALNT1,TMEM8B,SESN1,GPER1,INPP5B,ITPKB,NDP,MAPK7,ELOVL2,RIPOR1,SH3TC2,CSRNP3,ASAP3,FUZ,PEX26,LIMCH1,EXOC7,TK2,CBX5,BHLHB9,SPHK2,HPS4,PLSCR4,EPM2A,FZD3" Drug 2907_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AMT,CDC42BPA,PPFIA4,CAPN3,ENTPD6,HOMER3,PPP1R16B,RUBCN,DAPK3,GIT2,B3GAT3,SGSM2,DTNA,ING4,COQ7,ERAP1,COPS8,PRRC2B,MUM1,ATXN2L,ITGAM,JAK2,IPO5,CCSER2,MINDY2,PTPRN2,PTX3,TMEM231,DGLUCY,PEX26,ARHGEF40,KDM4C,ZBTB43,TSPYL2,NPDC1,PHTF2" Drug 2374_DN Diphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ALK,AMT,ARNTL,ARHGEF7,CD86,QKI,IQCK,COQ7,VPS26C,ZNF589,FHL1,ALDH1L1,AHDC1,TXNL4A,SPIN1,MSL3,LILRA2,KIF2A,LSS,NFYA,OCRL,OGG1,NLE1,SAMD9,TCP11L1,RASA3,FAM102A,FNDC3A,KDM4B,ZBTB43,DDN,SLC44A1,ZKSCAN5,PLPPR2,MPPE1,NLRP3" Drug 3397_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,NDRG2,LTBP4,BIN1,APC,BCAS1,ALDH7A1,GYG2,RCHY1,CSF1,KIAA0586,ELN,SPEG,ZNF589,FGF12,TMEM8B,TDRKH,ITPKB,JAK2,SMAD1,MSI1,NEK1,SETD4,PALM,RETREG1,RGS3,SUPT20H,ASAP3,PKNOX2,SMARCD3,SNCA,KIF13A,THSD1,PDIA2,WIPF1,DNALI1" Drug 2225_DN Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,ABHD6,AMPD3,CFLAR,SYNJ2,GYG2,SCARB1,HOMER3,PICK1,SLC4A8,HDAC4,ARMCX2,MFAP3L,DMPK,FER,TXNL4A,GLYR1,POLL,PRRC2B,DHX35,ITPKB,MMP16,NPR2,NLE1,SLC25A23,ZSCAN32,ZSCAN2,TCP11L1,FNDC3A,SYBU,SLC22A4,CDK5RAP2,THSD1,SEPT8,STX1A,TNS2" Drug 6844_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "EPB41L5,NCOA1,CNOT8,QKI,AKAP12,NCOR1,RIMS2,EXOG,ZNF589,FGF12,FGFR3,MALT1,GNG4,JAK2,KCNH2,MAPT,TM6SF1,MEIS2,NFYA,PCDH9,PRKAR1B,RGS12,SNCA,SPTAN1,SEPT8,TTBK2,ANKRD28,IQCE,CRTC1,TMEM121,SLC44A1,TK2,ZKSCAN5,ZBTB14,ZNF45,TFIP11" Drug 2308_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "LTBP4,APBB2,APC,PPP4R4,SLC4A4,SCAPER,HIP1R,RAB33A,CRMP1,FEM1B,EEF1D,EGFR,IP6K2,TXNL4A,MSL3,GSN,ELOVL5,TJAP1,KCNN1,NF1,SLC11A2,PRKAR1B,TCP11L1,CLIP1,ZNF821,FNDC3A,ZHX3,ZBTB43,VPS13A,TNS2,ACTR6,TRIO,HIRA,LMF1,WIPF1,XRCC4" Drug 1539_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "PLEKHB1,ARMC8,COL4A5,ARHGEF10,SIPA1L1,PDE4DIP,DZIP3,ARHGEF4,GPRASP1,DAPK3,HIPK3,SUGP2,MBNL2,DENND4A,EZH1,PDLIM5,GLYR1,GRB10,CACFD1,ATXN2L,LYRM9,NLE1,MBOAT7,PPP5C,TMEM104,FBXW7,FUZ,EPN2,BTBD7,SOX3,FNBP1,CLSTN2,POGZ,PLCB1,TMEM121,TPM1" Drug 1708_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRA1D,PDE8B,MARK4,SLC2A11,ALDH7A1,SCAPER,CA4,ARHGEF1,B4GALT6,GPRASP1,TBC1D5,LYPD1,NR1D2,EDNRA,MBNL2,PLEKHA1,ERAP1,SESN1,INPP5B,JAK2,NF1,NFYA,MAPK7,PTCH1,CEP97,GSTCD,FBXO11,FNDC3A,CDK19,ARC,DMXL2,TK2,TMPO,TPM1,REEP1,EPM2A" Drug 6147_DN Tropine [120-29-6]; Down 200; 28.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "BRAP,AMT,APBB2,PPP4R4,RAB33A,CRMP1,SLITRK5,MAML1,CNNM1,PLXNC1,PCOLCE2,C3orf18,ST3GAL6,PDLIM5,GAA,SEPT9,SPACA9,SLC2A6,TJAP1,IL6ST,ZNF862,NEK1,NELL2,RETREG1,RIPOR1,PPM1E,SNCA,ARHGAP26,DBNDD2,STX1A,JMJD6,DNMBP,AP4E1,PARD3,VIPR2,LMF1" Drug 6627_DN Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AP2A2,NME5,CDC42BPA,APOC1,SEMA4G,CDK13,KSR1,ST3GAL5,MYRF,CBFA2T2,SCARB1,LARGE1,STOML1,RAB26,HOMER3,CREM,SH2B1,NCOR2,DZIP3,EXOG,CNNM1,NOP56,GLYR1,POLL,SYNPO,KHK,NF1,FSD1,PRKAR1B,ZFP30,ZBTB43,DDN,ARHGEF9,KIAA0930,CRTC1,SEMA3B" Drug 3372_UP Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG2,KIAA1324,ATP2A2,BAIAP3,LDLRAD4,CFAP410,PLEKHB1,SULT4A1,COL9A3,NRG2,NCOR2,AATK,DGKG,BRINP1,RUSC2,SPOCK3,HS3ST2,EGFR,TNK2,ERCC2,PTK2B,FHL1,GLYR1,GRIK5,KIF5A,LMO2,KITLG,ZNF862,RFX2,SH3GL3,SLA,DICER1,GPR161,TRPM2,FLRT2,KCNAB1" Drug 2015_UP Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,APOC1,CDK10,ARNTL,ARRB2,BCL7A,CFLAR,RAB29,CAST,SCARB1,ARHGAP33,SOCS5,PPP1R16B,TNK2,RASGRP2,ATP2C1,FYB1,IRAK3,ATXN2L,NTRK3,PDE4D,PFKFB3,CCSER2,RETREG1,PPM1B,PPP2R2B,TCP11L1,ATXN7,ELMO2,KDM4B,AGTPBP1,FBXW11,HIRA,XRCC4,EVI5,SLC17A7" Drug 5642_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRA1D,C1QTNF3,APBA2,GAS7,CDC14B,N4BP2L1,NRP2,CA4,KYAT1,CHN2,WHRN,CRMP1,GREB1,DTNA,EDN3,TNK2,RCAN2,PDLIM5,KIF5A,MAN2A2,PALM,PDE4A,PLCD1,MAPK10,SH3BP2,KANSL3,PKNOX2,CXXC4,SNCA,TSNAXIP1,ATP10B,SLC44A1,TK2,VLDLR,PRDM10,KCNAB1" Drug 3517_DN Torsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ABHD6,PPFIA3,MARK4,CFLAR,BMP7,SYNJ2,ABI3BP,PDE4DIP,ARHGEF4,RUSC2,RCAN1,TSPAN5,RGS17,COQ7,BAIAP2,INPP5K,TXNL4A,MSL3,GPD2,HNMT,ADAM22,NPTX1,RETREG1,PLXNB1,FBXW7,RXRA,ASAP3,SLC22A4,ELOVL4,CEP68,VPS13A,ASTN2,TMEM121,AP4E1,LMF1,MAP3K12" Drug 3222_DN Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ABHD6,ARHGDIG,RGS20,SCAPER,USP2,QKI,MFAP3L,EDNRA,MBNL2,USP19,MALT1,HNMT,LIG4,MAP4,KITLG,MMP16,PCDH9,ZCWPW1,RGS12,EMID1,ZKSCAN3,SMARCD3,MAPKBP1,IQSEC2,THSD1,PLCB1,ASTN2,IQCE,TNS2,CHST8,HIRA,VIPR2,LMF1,MPPE1,EPM2A,UBE3B" Drug 2122_DN Nifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "PKP4,APBB2,CDC14B,CA12,RCBTB2,ZNF337,TBC1D5,MATR3,COQ7,CGREF1,TRAF3IP2,HTATSF1,GPER1,IFI16,SHISAL1,INPP5B,NACA,SLC11A2,RETREG1,NLE1,PLCD1,MAPK3,MAPK7,TMEM231,ZNF671,SBF1,SUPT20H,SH3BGR,ST6GAL1,ARHGEF9,EXOC7,FBXW11,HIRA,FAM155A,WIPF1,NAV3" Drug 4288_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADD2,AMPH,PKP4,APAF1,GAS7,SPTBN4,PTCH2,N4BP2L1,BMPR1B,CFAP410,CAMK2B,SYNGR3,CSF1,DBT,NR1D2,RASGRP2,DLC1,PDLIM5,GPER1,RASSF8,ICA1,KIT,MAP2,MAP4,GDPD2,CCDC40,CCDC102B,SH3BP2,DZIP1,ATP10B,SLC19A3,OBSL1,CBX5,TMPO,CHST5,MKRN3" Drug 1995_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; HL60; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ASIC1,NDRG2,AK2,CAMK2G,CD86,LRBA,TBRG4,SEC24C,DCAF8,EPB41L2,FGFR1,FAM49B,CACFD1,NCKAP1L,IFI16,INPP5B,MAN2A2,MAP4,MBD1,MYO9A,NF1,LRP12,MINDY2,PPP2R2B,C12orf49,ZNF671,SUPT20H,ZNF430,ERC1,CEP68,DIP2A,KANK1,TMPO,CHST5,LAT2,ITM2C" Drug 5984_DN Meticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "NDRG3,BRAP,AK2,APBB2,STX16,CFLAR,SYNJ2,MTMR2,B4GALT6,HOMER3,BAG4,CREM,PDE4DIP,GREB1,DBT,MBNL2,KAT8,SEMA4D,ANKFY1,GLYR1,MSL3,HTATSF1,IL6R,POLG,MINDY2,ELOVL2,RAD51D,GTDC1,ZNF430,ZBTB43,SS18,TTBK2,CHST8,TMPO,UBTF,EMSY" Drug 5228_DN 15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "AP2A2,FAM131A,PPFIA3,ARRB1,ARHGEF7,CACNA1I,RCBTB2,SLIT2,RAB26,PPP6R2,DCAF8,MFAP3L,MED12,DTNA,ZNF589,FGFR1,FGFR3,PRELID3A,MSL3,HNMT,MAN2A2,MMP16,NCAM2,NPTX1,PTN,RET,ASAP3,FUZ,SNCA,LHPP,THSD1,CEP68,MCF2L,TMEM121,GDPD5,SEMA3B" Drug 4644_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "APOC1,CDC14B,CACNA1I,CACNA2D1,RUNX1T1,CHN2,EPS15L1,AKAP6,SEC14L5,MFAP3L,PLXNC1,CALCRL,SPEG,EZH1,FGFR1,AFF2,CPLX2,GPR75,LILRA2,HLF,LMO2,NOVA2,NPTX1,PPP1R1A,PTPRG,MARCH1,C1orf54,SUSD4,MRAS,SLC11A1,SPTB,TACR1,DOCK9,TNS1,VIPR2,PARP11" Drug 1292_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "CDC42BPA,SLC4A4,ATP2A2,MTMR3,CFAP410,KYAT1,STOML1,PICK1,WHRN,ARHGEF10,CSNK1E,ZFYVE16,SGSM2,DTNB,FAM13A,COQ7,ZNF589,GAA,SRCAP,AHDC1,ZNF276,POLL,GRIK5,IFI16,NPR2,STRN3,PPP5C,RGS3,PPM1E,FUZ,PEX26,SMARCD3,IZUMO4,UNC5B,SIN3B,TNS1" Drug 4747_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADORA1,SYT13,CDC42BPA,MARK4,BACH1,SCAPER,GYG2,LDLRAD4,CNN3,CSF1,ARHGEF10,SPOCK2,TMCC2,HEYL,PTK2B,DLC1,OGA,SRCAP,CYP46A1,GPR75,GSN,AP4S1,ICA1,KIT,LAMA2,MAPT,NOVA2,NTRK3,CDK18,PDZRN4,KHDRBS2,CNKSR2,VSNL1,XRCC4,ITM2C,JPH3" Drug 1628_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "BRAP,EP400,CDK10,ARRB2,NCOA1,MPDZ,BCL7A,CCNT1,SCARB1,MAP4K4,RAB26,ARHGAP32,MED12,SUGP2,FGFR1,EFCAB2,CRCP,MSL3,HTATSF1,PRRC2B,FAM69A,ITPKB,KCNF1,MAP4,NFYA,SMIM7,DCUN1D2,ZNF331,SUPT20H,ABLIM3,SS18,KAT6B,PLPPR2,LMF1,KLC2,TFIP11" Drug 7391_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRB2,AP2A2,MYRF,KYAT1,ARHGEF1,TPP1,HOMER3,AKAP7,RCHY1,SLITRK5,CDON,DTNA,SPEG,ST3GAL6,BAIAP2,TRMO,FAM49B,TMEM8B,AHDC1,GPR37,MUM1,JAK2,GPSM2,PLCD1,FSD1,MAPK7,SAMD9,BCAS3,RGS3,KDM4D,CDK19,ZBTB43,DNMBP,PARD3,NAV3,PHTF2" Drug 6899_DN SB 203580; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADORA2A,CDC42BPA,MAGI1,CLGN,SOCS6,RAB28,TPP1,QKI,IQCK,CREM,TBC1D5,CNNM1,VPS26C,ZNF589,TRAF3IP2,USP19,GLYR1,BTN2A1,INPP1,PLCD1,MAPK7,C1orf54,ZDHHC14,SH3BP2,FRMPD1,PREX2,LIMCH1,UNC5B,ARHGAP26,IQSEC2,TRIM2,BEX4,TUBB1,LAT2,HPS4,TIGD6" Drug 6462_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "MTUS1,AMPD3,BIN1,CFLAR,GYG2,CAMK2B,BAG4,PDE4DIP,GIT2,TOM1,OPTN,TRMO,PRELID3A,DISC1,MALT1,TXNL4A,TDRKH,PADI2,KCNF1,MGAT3,NF1,NPTX1,PDE4B,PLEC,PTPRE,RGS3,RPS6KA2,CXXC4,ERC1,ITPRID2,ASTN2,MCF2L,THRA,TK2,UBTF,SEMA3B" Drug 7123_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADCY6,BIN1,BID,LHX2,HAPLN1,CRY2,OSBPL3,CNTNAP2,DYNC1I1,HIPK3,ETV1,TRMO,DENND2A,GAD1,ERAP1,TMEM8B,SESN1,ZNF276,TM6SF1,NEK1,NPR2,SLC25A23,KLK6,CNNM2,PTN,MYH15,PHLDB1,ARHGEF9,WSCD1,TCF4,TRIM2,NSD1,DICER1,ZFPM2,TK2,SMIM8" Drug 4206_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 1.67E-02 1.88E-01 36 196 "ADRA1D,TRMT9B,APC,ARRB2,NRG2,HAPLN1,RGS6,ARHGEF10,FYB1,DISC1,SEPT9,GRM8,SOX21,SHISAL1,MGAT3,TAGLN3,ZNF862,PDE4D,ENPP2,SLC25A23,PLXNB1,MAPK7,PTPRB,ZCWPW1,KHDRBS2,RGS4,MRAS,FRMPD1,KANSL3,MYH15,DDN,THRA,VIPR2,NT5M,VPS35L,KCNAB1" Drug CID000000194 AC1L1IO7 Stitch 2.46E-03 1.00E+00 1.67E-02 1.89E-01 17 72 "ADORA1,ADORA2A,AMPD2,AMPD3,P2RX6,ENTPD2,GMPR2,LPAR4,MBP,P2RY13,P2RX7,P2RY1,ENPP2,APTX,SARS,DDN,P2RY12" Drug CID000065072 homocitrulline Stitch 2.47E-03 1.00E+00 1.68E-02 1.90E-01 7 18 "CPS1,EPB41,GATM,CIT,SIRT2,SIRT1,NETO1" Drug CID000122081 LOE 908 Stitch 2.47E-03 1.00E+00 1.68E-02 1.90E-01 7 18 "ASIC1,CACNA2D1,EDN1,EDNRA,EDNRB,PTK2B,MAPK3" Drug CID000001388 MPTP-HCl Stitch 2.47E-03 1.00E+00 1.68E-02 1.90E-01 31 162 "ADORA2A,APAF1,APLP1,ARHGDIG,BCHE,CALB1,CALB2,CDO1,CHRNA4,EYA1,PPP1R1B,GAD1,LOXL3,GPR37,GRIN2C,GRIN2D,GRM2,GRM8,LINGO1,SLC11A2,OGG1,POU6F1,PTPRD,QDPR,HSPA4L,SNCA,MGRN1,TK2,TMPO,SMUG1,PDIA2" Drug CID000015910 chlorothalonil Stitch 2.47E-03 1.00E+00 1.68E-02 1.90E-01 31 162 "AP2A2,SEMA6A,APAF1,NRP2,DBI,DYNC1I1,RCAN1,RCAN2,ERBB2,F8,PPP1R1B,FOLH1,GALC,PPARGC1A,LYVE1,TCERG1,PACSIN2,RBPJ,NCF2,NELL2,NPTX1,OGG1,FSD1,QDPR,FBXW7,ATXN7,FOXRED1,ARX,CYB561A3,SEMA3B,JPH3" Drug CID006857364 AC1OAGGW Stitch 2.47E-03 1.00E+00 1.68E-02 1.90E-01 37 203 "BIN1,ARHGDIA,BTK,CALM1,DGKI,SEPT7,CRLF1,CLTC,PLCXD3,DGKB,DGKG,SNAP91,DNM1,DNM1L,PHC2,EPB41,EPB41L2,FECH,PLCD4,GSN,KCND1,OCRL,PIK3C2A,PIK3R1,PLCB2,PLCD1,PPP2R2B,PRKCB,PTK2,RDX,KCNIP1,PLCB1,DNMBP,ACTR6,TNS1,VSNL1,PLD4" Drug ctd:D000393 Air Pollutants CTD 2.48E-03 1.00E+00 1.69E-02 1.90E-01 132 918 "DGCR6,AS3MT,NDRG2,ZNF608,TXNDC16,CEP126,CARNS1,MARCH4,APAF1,CDC14B,ARRB1,ARSE,PTCH2,RNF182,ARHGEF7,SCAPER,CASTOR3,C5,IL33,CA12,CACNA2D1,CALB1,SCARB1,LRBA,DCLK1,LRRFIP1,LARGE1,CCPG1,FOXN3,ABCG2,FAM149A,LETMD1,AKAP12,LRIG1,VCAN,DZIP3,CCDC144A,TBC1D5,DAPK1,ELMO1,RHOBTB1,HS3ST2,USP3,CD99L2,NR1D2,DNAJB6,EIF4G1,ING4,SRPK3,EPB41,RAB9B,ERBB2,NCALD,NSRP1,FAM198B,RPS6KC1,GTF2IRD2,FHL1,IP6K2,NBEA,ZNF234,IQGAP2,ERAP1,GATM,TUBA8,PPARGC1A,MSL3,PRDM5,HAS2,FRMD3,TNFAIP8L3,HMGCL,HNF4G,LIG4,MATN2,MEIS2,MIA2,AFDN,PTOV1,NFE2L2,OGG1,OXTR,ETFRF1,PCDH9,PDE3A,PFKFB3,SMOX,CNNM2,SAMD9,BCAS3,VPS13C,SPDL1,PTPRD,ZFHX4,CARF,ROBO1,PCMTD2,CCDC102B,MRAP2,NEK11,PTGR2,FNIP1,HKDC1,ST6GAL1,LIMS2,CDK5RAP3,CXXC4,SPATA7,KDM3A,NMNAT2,SPP1,PBLD,ITPRID2,ADHFE1,SYNE2,DMXL2,SLC19A3,USP32P1,TNS2,TP53BP1,SSBP2,TST,GORASP1,PLEKHH2,XRCC4,KCNT2,TRIM9,FSTL5,CADM2,NAV3,MARCH8,FRMD6" Drug CID000000650 "2,3-butanedione" Stitch 2.48E-03 1.00E+00 1.69E-02 1.90E-01 22 103 "ACADM,MYH7B,ATP2A2,LDHD,CD38,B3GAT3,EXOG,DTNB,TMTC1,AASS,POLK,GPD1,GPD2,GSN,MYLK2,ASPRV1,MEF2C,ZNF655,RDX,SHMT2,ADHFE1,TMPO" Drug CID000001257 LY 171555 Stitch 2.49E-03 1.00E+00 1.69E-02 1.91E-01 28 142 "ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,CCK,LRBA,CNR1,HDAC4,RGS17,PTK2B,PPP1R1B,GAD1,GNAO1,GRIA2,GRIN2C,GRIN2D,CIT,KCNJ5,NPY,OPRL1,PRKACB,MAPK3,SST,MLST8,ZNF106" Drug CID000001123 taurine Stitch 2.50E-03 1.00E+00 1.70E-02 1.91E-01 41 231 "ADORA2A,ADRA1B,ATP1A3,BID,CBS,KRIT1,CDO1,CHN1,CLCN3,HAPLN1,PPP1R16B,CTH,EDN1,RASGRP1,FGFR1,GABRA3,GABRB3,GABRG2,GAD1,GGT7,GGT5,GLUL,GRIN2C,GRIN2D,CIT,KCNJ16,MAPT,FXYD1,PPP2R2B,PPP2R5E,MAPK3,MAPK4,MAPK7,KLK6,GSTCD,SLC6A11,TACR1,XRCC4,SLC17A7,NETO1,ST8SIA2" Drug ctd:D010795 Phthalic Acids CTD 2.52E-03 1.00E+00 1.72E-02 1.93E-01 113 770 "SYN3,PLEKHH1,ADRA1B,MTUS1,TBC1D14,CC2D2A,SRPX,CDC14B,CADPS,ZBTB10,STX16,KIF1A,CALB2,NFS1,CBLN1,SCARB1,CHRNA4,CNN3,MYRIP,ZNF521,ABCG1,PDE4DIP,RUBCN,DBI,ZC3H11A,SACS,FAM107B,DYNC1I1,EDNRA,KLHL5,TMEM132E,KCTD3,EIF4G2,NCALD,MRPL37,ETV1,ACSL4,ST3GAL6,FDFT1,OLFM1,FGF13,BAIAP2,TMEM164,POMT1,NSG1,MPP6,OGA,GAA,CPLX2,ALDH1L1,SESN1,GGT7,RNPS1,HPGDS,HTATSF1,TDRKH,GRB10,ZNF496,ELOVL5,HMGCR,HP,KIF2A,KIFC3,IPO5,LSS,PIK3AP1,GPR155,DBNL,MYO9A,NPTX2,TBC1D25,TREM2,ETFRF1,PFKFB3,ABCB1,ZNF655,DRAM2,TTC13,PID1,FAT4,RGS12,CYB561D1,RORB,SBF1,SCP2,TRA2B,SGK1,KIF21A,ANKRD6,SEPHS1,ATF7IP,CDK5RAP2,FAM126B,STXBP1,AGTPBP1,KLHL4,NSD1,DICER1,TNS1,TPM1,TPM2,TST,FAM155A,PLEKHH2,VSNL1,ZNF142,ANKS1B,STOX2,WNK3,HRASLS,AMN1,IFT88,RNF146" Drug CID000061492 cobalt-60 Stitch 2.53E-03 1.00E+00 1.72E-02 1.94E-01 63 390 "METAP1D,ADCY5,ADCY6,ADCY8,PITPNM2,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CACNA2D2,CLTC,FBXO7,CNR1,PREPL,ARHGAP32,HEPH,DTNB,CNNM1,TUBD1,FECH,FLT1,TUBA8,GGT7,GGT5,GRIA2,GRIK4,GRIK5,CLASRP,HBA1,TNFAIP8L3,IGF1,LAMA2,MAT2A,NEFM,NPY,SLC11A2,PDE4A,ENPP2,PKD1,PKM,PPP3CA,PPP3CC,CNNM2,LAMA1,PTGR2,RYR3,COPZ1,SLC11A1,HECW1,PEG10,ADHFE1,TPCN2,CYB561A3,CABIN1,TUBB2A,TUBB1,SLC30A3,SLC30A4,PLD4" Drug ctd:D015632 "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine" CTD 2.56E-03 1.00E+00 1.74E-02 1.96E-01 53 317 "SYN3,ACHE,ADORA2A,ARRB1,KIF1A,CFLAR,CALM1,SYNGR3,SEPT7,CHRNA4,PLAA,ABCG2,SNCAIP,CST3,PNPLA8,DPYSL2,PDCD6IP,GOLT1B,EIF5,TNK2,ENO2,MRPL10,PPP1R1B,FYN,GAD1,LPAR4,HBA1,IDH3A,KIF5A,STMN1,SMAD1,MAP2,MAPT,NFE2L2,SH3KBP1,PPM1B,MAPK3,PPP2R3C,RET,LRRK2,SMPD3,RASA3,SNCA,JMJD6,CBX5,TLR4,KAT6B,NPL,UBC,UCHL1,MTCH1,MAP3K12,TUBA1A" Drug 2926_UP Zardaverine [101975-10-4]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 1.75E-02 1.98E-01 33 176 "BIN1,APBB2,FAM131A,PRX,DNAH17,SLC2A11,MYOM1,CD86,CD38,CHN2,CREM,SIPA1L1,PPP1R16B,DOCK4,SPOCK3,FAM13A,DLC1,BAIAP2,SAMD14,ZNF862,NOVA1,PDE4B,PDE4D,PFKFB4,PGAM2,SERPINI1,TCP11L1,SPTAN1,PCDHA5,ZFPM2,TNS1,ZBTB38,KAT6A" Drug CID000099735 4-hydroxycyclophosphamide Stitch 2.58E-03 1.00E+00 1.76E-02 1.98E-01 11 38 "ALDH7A1,CRLF1,CLTC,AASDH,LYVE1,PDE4B,PBRM1,GSTCD,AP1AR,PEG10,SYNE1" Drug CID000017699 propinox Stitch 2.59E-03 1.00E+00 1.76E-02 1.98E-01 13 49 "BRAP,BBOX1,CAPN3,TIGD7,CSNK1E,DCTN1,DMD,FKTN,AGAP2,ITGA7,PPP3CA,RNH1,NETO1" Drug 7154_UP Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.62E-03 1.00E+00 1.78E-02 2.01E-01 34 183 "LGR5,KRIT1,SCARB1,HOMER3,BAG4,CREM,DTNA,YAF2,MBNL2,FGF1,BAIAP2,AMOTL2,TRMO,PDLIM5,GAD1,IL6ST,LSS,AFF1,PDE1C,LRP12,PRKAB2,PTX3,CLIP1,SEC14L1,FNDC3A,TMCC1,SYT1,PDLIM2,TK2,TRIO,EVI5,NAV3,UBE3B,RNF170" Drug 6737_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.62E-03 1.00E+00 1.78E-02 2.01E-01 34 183 "AGT,NME5,EPB41L5,BCAS1,FUBP1,IL33,SCARB1,ARHGAP33,CACNA2D2,CREM,CTH,TENM1,ETV1,F5,DLC1,GLYR1,KCNN1,MMP16,MX1,PALM,PDE4D,GPR85,PFKFB3,DUSP26,SNRK,RGS12,ARHGAP26,ATP10B,CEP68,SYT5,MCF2L,TBL1X,TK2,PARP11" Drug 1154_UP 17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.62E-03 1.00E+00 1.78E-02 2.01E-01 34 183 "APBB2,CFLAR,CAST,CREM,CRY2,TBC1D5,DAPK1,DBT,KIAA0753,RUSC2,DTNA,FAM13A,MBNL2,CAMKK2,DISC1,KCNMB4,NINJ2,PDE4B,MBOAT7,PRKACB,PTK2,RPS6KA2,HSPA4L,NUBPL,BTBD7,IQSEC2,EXOC7,TK2,KAT6B,LMF1,ZNF32,MPPE1,PHTF2,FXR1" Drug 6874_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.62E-03 1.00E+00 1.78E-02 2.01E-01 34 183 "ADRB2,EPB41L5,ARNTL,ST3GAL5,PDE4DIP,CTH,SPOCK3,FDFT1,BAIAP2,PDLIM5,DISC1,GUCY1B1,MAP2,MAPT,MBD1,MMP16,PCBP3,PCDH9,SERPINI1,RETREG1,FSD1,PRPH,RGS4,SH3GL3,FAM214B,SPTAN1,THSD1,CEP68,RGL1,SYT1,TNS1,UBE2H,SLC17A7,DPF3" Drug 6185_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.62E-03 1.00E+00 1.78E-02 2.01E-01 34 183 "APAF1,APC,CDC14B,SLC4A4,CFLAR,CREM,CRYM,TM9SF4,MFAP3L,SPOCK3,FAM13A,MBNL2,OGA,NEFM,PCSK5,PDE4B,PDE4D,RETREG1,PMP22,MBOAT7,PRKACB,CNNM2,CNTLN,CRTAC1,HSPA4L,SH3GL3,LHPP,ATP10B,ASTN2,LMF1,VSNL1,CLIP2,ZBTB38,PRDM10" Drug 3848_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "SEMA6A,APOC1,ADAM15,ADGRB1,CNTFR,IQCK,WHRN,NCOR2,SEC14L5,DAPK3,TMCC2,FCF1,ING4,ANKFY1,KHDRBS3,GLYR1,GPER1,GSN,HLF,IL6ST,KCNH2,LSS,MID1,MYT1,NNAT,CLDN11,CDK18,MASP1,RGS12,KCNIP1,TBCEL,UBE3A,FLRT2,NT5M,SENP7" Drug 5942_UP LY294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "AP2A2,AGT,APOC1,CDK13,CAMK2B,CPS1,AKAP12,EZH1,ERAP1,SESN1,KCNMB4,TDRKH,STON1,SPACA9,ICA1,ITGA7,ZNF862,NF1,PDE4D,SERPINI1,PIK3R1,CNNM2,CCDC40,TCP11L1,RPS6KA2,ZNF667,SNCA,IQSEC2,TROVE2,CEP68,TK2,TRIO,VIPR2,PLSCR4,TIGD6" Drug 4306_DN Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "RALGAPA1,NME5,SRSF11,B4GALT6,ABI3BP,ENTPD4,ARHGAP24,NR1D2,DTNA,EDIL3,ING4,FER,FGF13,SPIN1,HTATSF1,HAS2,AGFG1,IFI16,IL6ST,MAP4,MIA2,NFIX,STRN3,LRP12,SLC25A36,KIRREL1,ZBTB43,TTBK2,TBL1X,DICER1,TMPO,ZNF24,ZBTB38,EVI5,KAT6A" Drug 4322_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "PKP4,PDE8B,SRSF11,CRMP1,CNTNAP2,SPOCK2,CHRDL1,EDIL3,FCF1,MBNL2,ING4,PDLIM5,CRCP,GPD2,SPACA9,RASSF8,AGFG1,IFI16,IL6ST,MAP4,CNOT4,STRN3,LRP12,MINDY2,PRKAB2,C1orf54,KIRREL1,PPP4R3A,TIAM1,TMPO,OSBP2,EVI5,KCNAB1,KAT6A,PHTF2" Drug 3833_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "BIN1,TAOK2,AKAP7,RIMS2,DAPK3,MBNL2,PLEKHA1,VPS26C,BAIAP2,FHL1,ANKFY1,INPP5K,GLYR1,GPD2,MAP4K5,INPP5B,MBD1,ADAM22,NEK1,NFYA,NPR2,SERPINI1,PLCD1,PLEC,ZDHHC14,RGS12,GSTCD,EMID1,ASAP3,FUZ,ELMO2,SPTAN1,TRIO,ZKSCAN5,MAP3K12" Drug 5926_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.65E-03 1.00E+00 1.78E-02 2.01E-01 35 190 "ADORA1,MTUS1,CDC42BPA,ARHGDIG,CACNA1I,LDLRAD4,CA12,SLC16A4,EPS15L1,GREB1,MFAP3L,DMPK,CDON,RASGRP1,EGR3,FGF12,GRIK5,ICA1,KCNF1,PCBP3,PDE4A,PFKFB3,LRP12,GAL3ST4,RET,ZFHX4,SGK1,PREX2,LIMS2,DOP1A,TSNAXIP1,TBCEL,TRIM2,SZT2,DNALI1" Drug 4440_DN LY 294002; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AK2,ADGRB2,IL33,CFAP410,KRIT1,SCARB1,SOCS6,CHN2,AKAP7,BAG4,HIPK3,SUGP2,STX2,EZH1,DENND2A,B4GALNT1,KCNMB4,GUCY1B1,IL12A,MT1M,ZNF862,PDE4D,FSD1,CNNM2,RBBP6,RPS6KA2,RXRA,FBXO11,KDM4C,SAMSN1,IQCE,CRTC1,GPR161,ZNF711,NT5M,UBE3B" Drug 3894_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NME5,DOC2A,BIN1,GAS7,APLP1,SLC2A11,ALDH7A1,CA4,SCARB1,CSF1,CSF1R,RIMS2,USP6NL,DAPK3,EXOG,HSD17B14,SCML2,ZNF589,FYN,GCNT2,GPD2,LMO2,MATK,KITLG,NF1,NTRK2,CCDC40,RASA3,SH3BP2,BTBD7,CDK5RAP2,EXOC7,SMG6,TNS2,SLC44A1,ST7" Drug 2490_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AGT,ATP2B2,LDLRAD4,CAMK2B,MAGI1,CDO1,CACNA2D2,CABP1,CREM,SPOCK3,TMCC2,SHANK1,TOM1,OPTN,CDKL3,AGAP2,AFF2,CAMKK2,SIGLEC8,STON1,GRIK5,HNMT,IL6ST,KCNJ5,MAPT,MEF2C,STRN3,PPP2R2B,VPS13C,PPM1E,RBM34,ZC3H13,LHPP,SEPT8,SYT5,OBSL1" Drug 2307_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,MTUS1,SRPX,SEMA7A,APC,ARRB1,CDK13,MARK4,CFLAR,C5,B4GALT6,SH2B1,DZIP3,SPATA2,SUGP2,ACSL4,TXNL4A,ELOVL5,MAP4,GIT1,CNOT4,NTRK2,PPP5C,PPP4R3A,BTBD7,MAPKBP1,ZHX3,CAMTA2,EXOC7,FBXW11,CRTC1,CABIN1,CDK20,XRCC4,ZNF24,EPM2A" Drug 4022_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ALK,KIF1A,NRP2,FOXN3,ARHGAP22,EPS15L1,PICK1,WHRN,PARD6A,EXOG,PLXNC1,COQ7,MTSS1L,ETV1,FGF1,AFF2,SYT17,INPP5K,GFER,ZNF276,GLI2,TDRKH,GRM8,MX1,NPR2,FA2H,POLG,TMEM231,SH3TC2,KCTD17,ASAP3,MYH15,DNAH7,THRA,TK2,UPF3A" Drug 6359_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MTUS1,AK2,APOC1,PPFIA3,QKI,VCAN,INTS1,GIT2,PLPPR4,SLC12A6,ANKMY1,FGFR1,PRELID3A,INPP5K,L1CAM,MX1,FA2H,FUZ,NUBPL,SMARCC2,TMCC1,ZBTB43,THSD1,SS18,STX1A,SYN2,EXOC7,TRIM2,CHST8,TK2,SSBP2,ZKSCAN5,HIRA,UBTF,NDRG4,EMSY" Drug 2457_DN Hexetidine [141-94-6]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BRAP,SRPX,AMPH,APBB2,APOC1,ATP2A2,SCAPER,CFAP410,TPP1,ARHGEF10,DGKG,NR1D2,DTNA,FEM1B,PLEKHA1,TNK2,C3orf18,RASGRP2,NCALD,MAP4,SCAMP5,MYO7A,NF1,PMP22,PRKAR1B,MAPK10,ZNF493,EMID1,SLC11A1,IQSEC2,ZC4H2,ADGRL3,TNS2,CRTC1,LAMP5,ZNF225" Drug 7241_DN Mesalamine [89-57-6]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,EPB41L5,SYNJ2,VAX2,HOMER3,ARHGEF6,LRIG1,PDE4DIP,DCTN1,LYPD1,CDON,EGFR,MBNL2,ENO2,DENND4A,FAM49B,DISC1,SRCAP,IL6ST,INPP5B,MPP2,CNOT4,RETREG1,PLEC,MBOAT7,PRKAR1B,RIPOR1,SBF1,MAPKBP1,KDM4C,ZBTB43,CLASP2,ARHGEF9,MAP3K12,SMIM8,TIGD6" Drug 2720_DN Isopropamide iodide [71-81-8]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NUMB,SYNJ2,LDLRAD4,ARHGEF1,CLGN,EPS15L1,AKAP7,ARMC8,NRG2,ENTPD4,SH2B1,CSF1,PDE4DIP,SLC12A6,CDKL3,FHL1,FAM49B,OGA,SEPT9,GPR75,MSL3,LPAR4,MAP4,SLC11A2,PLTP,ZCWPW1,SEC14L1,ANKRD6,SLC11A1,RBM26,KANK1,PLPPR2,XRCC4,URM1,NLRP3,TIGD6" Drug 4948_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,SPARCL1,SYNJ2,LHX2,HOMER3,CNTN1,CSNK1E,MFAP3L,CDON,EDNRA,RASGRP2,GAD1,SRCAP,USP19,ICA1,IFI16,JAK2,KPNA5,MIA2,RETREG1,PLTP,MTRF1L,PNMA8A,ASAP3,FUZ,SNAP25,ZHX3,ZC3H13,ZBTB43,WSCD1,ZEB1,CABIN1,WIPF1,XRCC4,SLC17A7,MPPE1" Drug 7424_DN Prednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,FAM131A,CDC14B,CBFA2T2,SCARB1,CSNK1E,PDE4DIP,KIAA0586,PARD6A,MED12,SUGP2,TNK2,EFCAB2,FYN,ATXN2L,NEK1,NF1,RGS3,FBXW7,TRAPPC13,SEC14L1,SH3BP2,FERMT1,PEX26,ARFGAP1,ZKSCAN3,TTC17,KDM4B,LHPP,PHLDB1,NSFL1C,MTCL1,HIRA,UPF3A,SEMA3B,KAT6A" Drug 3769_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,AMPH,PDE8B,ATP1A3,MTMR3,KALRN,EPS15L1,SULT4A1,AATK,SUSD5,ERC2,DTNA,RASGRP2,OLFM1,PDLIM5,ALDH1L1,SRCAP,POLL,GNAL,GRIK5,ICA1,KIFC3,TAGLN3,TREM2,CDK18,PIK3R1,NECAB2,CNKSR2,ATP10B,MCF2L,TAL1,CRTC1,TLR4,RIMBP2,TUBB1,ZNF225" Drug 3071_DN Estrone [53-16-7]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APOC1,MYRF,HIP1R,SCARB1,HOMER3,DGKG,DBN1,FEM1B,OPTN,RASGRP2,CD320,CGREF1,CSPG5,SEPT9,SRCAP,LAMA2,ZNF862,NINJ2,PLTP,MAPK7,BEND5,PPM1E,AMBRA1,SNCA,KDM4B,DOP1A,JMJD6,PLCB1,ADGRL3,DMXL2,NSD1,ZNF34,FLRT2,UBE3B,NLRP3,TIGD6" Drug 5751_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,APBB2,APC,GAS7,ARHGDIG,ATP6V0A1,CLTB,COL9A3,NCOR2,ABCG1,C2CD2L,HIPK3,SEMA3D,FGF1,ALDH1L1,SRCAP,COPS8,GLYR1,SPACA9,ELOVL5,KHK,KIT,LSS,NF1,NRCAM,PDE4D,GPR85,PPP5C,PTN,ACSS3,SPTB,LHPP,TROVE2,POGZ,TBCEL,VAV1" Drug 2439_DN Menadione [58-27-5]; Down 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APOC1,BARD1,LDLRAD4,ARHGAP33,CLGN,STOML1,ARHGEF10,SLITRK5,RHOBTB1,DTNA,RASGRP2,SYNCRIP,ERAP1,SEPT9,GLYR1,LILRA2,KCNN2,NPR2,SLC11A2,SLC25A23,MAPK7,TMEM104,C1orf109,TTC13,GTDC1,RPS6KA2,DGLUCY,ZSWIM8,TK2,CBX5,TMPO,PARD3,TNS1,ZBTB14,HPS4,EPM2A" Drug 3484_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "SPARCL1,ALCAM,TRMT9B,APOC1,MARK4,ABCG1,DCAF8,ERCC2,DCTN2,DLL3,STON1,ELOVL5,TJAP1,INPP5B,KCNH2,MAP4,ZNF862,PDE4B,SMOX,VPS13C,FAM184A,ZDHHC14,RGS12,SH3BP2,BTBD7,SPTAN1,ST5,MTCL1,EXOC7,SMG6,KIAA0930,CRTC1,AMACR,VGF,XRCC4,KCNAB1" Drug 6824_DN Napelline [5008-52-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,ADRA1D,SEMA6A,CDC14B,ARRB1,NCOA1,RIMS2,TOM1,FEM1B,IRAK4,ING4,CDKL3,KAT8,DISC1,GLYR1,GNG4,PADI2,KCNH2,LIG4,TM6SF1,KITLG,LYRM9,PRKAR1B,ELOVL2,ZSCAN32,SH3BP2,FBXO11,SLC9A5,SNCA,CDK19,CEP68,STX1A,IQCE,ZNF34,PCBP4,ST7" Drug 2819_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,AMT,PPFIA3,N4BP2L1,SCAPER,CACNA1I,BAIAP3,CA4,CAMK2G,SLC16A4,NECTIN3,CNTNAP2,HS3ST2,HSD17B14,STX2,FGF12,FHL1,FYB1,GPER1,MMP16,NF1,LRRN3,RELN,PTCH1,ZMAT4,RGS3,TCP11L1,MRAS,NLGN1,PKNOX2,ARHGEF40,PCDHA5,CABIN1,VIPR2,ZNF45,SEMA3B" Drug 7169_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,AK2,BIN1,ARHGEF7,SCAPER,ARHGEF2,FAM189A2,HAPLN1,SOCS5,PDE4DIP,GIT2,LYPD1,CDON,RCAN1,DTNA,MBNL2,CDKL3,BAIAP2,FHL1,SYT17,GNG4,GRM8,KCNN1,LMO2,LSS,LRRN3,MAPK7,PRPH,SAMD9,RIPOR1,ZDHHC14,RPS6KA2,FRMPD1,SLC11A1,TTBK2,VPS13A" Drug 2304_DN Mephenesin [59-47-2]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AK2,CDC42BPA,PPFIA3,MARK4,SYNJ2,CNOT8,CRY2,ABCG1,DAPK3,CELSR3,BAIAP2,KCNMB4,CNTRL,ATXN2L,MIA2,MPP2,SLC11A2,NTRK2,PALM,MBOAT7,PRKAR1B,CEP97,SBF1,SH3BP2,ANKRD6,PPP4R3A,EPN2,ELMO2,BTBD7,KDM4C,SS18,ST5,ARHGEF9,COBL,SLC44A1,WBP2" Drug 4673_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADGRB2,BMP7,HAP1,CAMK2B,LDB2,PLEKHB1,HOMER3,ABCG1,CSF1,TBC1D5,PLPPR4,DTNA,ETV1,OLFM1,LYVE1,GLYR1,CACFD1,JAK2,LIFR,PCBP3,RETREG1,PPP5C,MAPK3,CNNM2,PTCH1,RAD51D,GTDC1,RGS12,SUPT20H,PHLDB1,EXOC7,TBCEL,TCF4,CHST8,ZNF34,ZNF24" Drug 6840_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,C1QTNF1,BEGAIN,AMH,ALDH7A1,BAIAP3,CACNA1A,ARHGEF1,CLGN,CHN2,TAOK2,FAM149A,CRMP1,NCOR2,CSF1,KIAA0319,ERCC2,BAIAP2,HPCAL4,SIGLEC8,SRCAP,GRM2,HNMT,KCNN2,KCNQ3,PDE1C,PDE1B,PLCD1,TCP11L1,SCN2B,FAM214B,ARHGAP26,TRIM2,ZKSCAN5,FAM155A,VIPR2" Drug 6863_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "LTBP4,ADGRB2,BAIAP3,CBFA2T2,TAOK2,QKI,PICK1,SH2B1,DZIP3,MFAP3L,PTK2B,FGFR1,LPAR4,KCNJ5,KCNN1,TAGLN3,MX1,NLE1,STRN3,FSD1,PRKAR1B,MAPK7,PBRM1,TRAPPC13,SBF1,ZNF821,FUZ,PEX26,BTBD7,CDK5RAP2,KDM4B,SPART,CEP68,BEX4,TRIO,LMF1" Drug 3192_DN Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADRA1D,TRMT9B,APOC1,ARRB1,CFAP410,CAMK2G,CRLF1,SOCS6,PLEKHB1,HOMER3,CRY2,NCOR1,FAM169A,CTH,PPP6R2,VPS13B,FGFR1,BAIAP2,FAM49B,TRAF3IP2,CNTRL,HNMT,LMO2,MSI1,NNAT,PRKAR1B,RAD51D,RGS3,RGS12,KIF13A,ST5,EXOC7,TRIM2,CRTC1,SLC44A1,THRA" Drug 3216_DN Hemicholinium bromide [312-45-8]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,AMPD2,BIN1,APLP1,FAM131A,BCAS1,PPFIA3,RGS20,ST3GAL5,SYNJ2,EPS15L1,QKI,CREM,DMPK,FCF1,RASGRP2,MTSS1L,SPACA9,GRM8,KPNA5,LIG4,MITF,MMP16,NEK1,PLTP,GTDC1,CCDC25,ZNF821,BTBD7,KDM4C,NXT2,PLCB1,ZNF34,TMPO,VIPR2,REEP1" Drug 2371_UP Lisinopril [83915-83-7]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "PRX,C5,VAX2,FAM149A,AKAP6,PPP1R16B,ERC2,MFAP3L,DTNA,CDKL3,GALC,ALDH1L1,GLYR1,GRIK5,GRM8,NXPH3,ATXN2L,KCNH2,KCNN1,NPR2,PDZRN4,MINDY2,CNTLN,RGS3,SH3BGR,LIMS2,CXXC4,RBM34,SOX15,SEPT8,PDLIM2,IQCE,WSCD1,ZNF34,FLRT2,SPHK2" Drug 2492_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG3,APBB2,FAM131A,APOC1,PPP4R4,NCOA1,ADAM23,SGCE,LDLRAD4,SOCS6,EPS15L1,RAB33A,CNTN1,AATK,TSPAN5,PIPOX,SEPT9,INPP5K,SRCAP,TJAP1,ZNF862,PLCD1,CNNM2,PTN,PTPRN2,MRAS,ANKRD6,PREX2,SLC11A1,TROVE2,PDLIM2,OBSL1,TK2,XRCC4,ZNF23,NT5M" Drug 6061_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASPHD1,SEMA7A,APAF1,APC,SEMA4G,CFAP410,HAP1,ARHGEF2,SEPT7,TPP1,LY86,RCHY1,CRMP1,CSF1,FAM169A,GREB1,SEC14L5,EDNRB,HIPK3,DLC1,FHL1,GAD1,GLYR1,GPD2,KCNH2,ADAM22,RETREG1,POLG,TCP11L1,SBF1,TROVE2,PLCB1,EXOC7,PDLIM2,XRCC4,DPF3" Drug 5081_DN Perhexiline maleate [6724-53-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADAM15,ARHGEF7,SCAPER,CBFA2T2,CHN2,CSF1R,PPP6R2,RUSC2,PARD6A,EDIL3,MBNL2,SPEG,ETV1,TRMO,DENND2A,GAD1,SRCAP,CNOT4,PLCD1,FAT4,GTDC1,MAPK12,WDR37,DHX30,THSD1,SS18,CRTC1,ZNF34,BEX4,CABIN1,TPM2,PLPPR2,LAT2,MAP3K12,VPS35L,FZD3" Drug 2361_UP Indapamide [26807-65-8]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MTUS1,SEMA6A,CDK13,MARK4,BMP7,BAIAP3,LDLRAD4,SH2B1,VCAN,DAPK1,ANKFY1,CELF1,DLL3,CHL1,INPP5K,LPAR4,KCNJ5,KHK,GIT1,MYCN,NELL2,OXTR,PFKFB2,MTRF1L,FRMPD1,ANKRD6,PKNOX2,TMCC1,KDM4C,ATP10B,SS18,SYN2,EXOC7,CDK20,VLDLR,EVI5" Drug 7317_DN Quinic acid [86-68-0]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,APOC1,ST3GAL5,SCARB1,TAOK2,NCOR2,CDON,DPH1,TENM1,MRNIP,EZH1,SCML2,ZNF589,B4GALNT1,USP19,CNTRL,SHISAL1,JAK2,KIFC3,MAN2A2,NF1,GTDC1,GSTCD,FBXW7,RPS6KA2,SAFB,SBF1,FUZ,WDR37,MYH15,SZT2,TNS1,HIRA,EVI5,KAT6A,PHTF2" Drug 3225_DN Ascorbic acid [50-81-7]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,BRAP,ADORA1,AP2A2,BIN1,APBB2,APC,MARK4,BMP7,KYAT1,USP2,CRLF1,EPS15L1,NCOR1,CSF1,PDE4DIP,HDAC4,MFAP3L,CDON,ANKFY1,GRM8,RNFT2,ATXN2L,ELOVL5,LMO2,MBD1,NEK1,SAMD9,RGS12,CCDC25,FAM192A,RASA3,NLGN1,PKNOX2,CLASP2,MCF2L" Drug 3693_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "FAM135A,SEMA7A,ATP2A2,SLC2A11,BACH1,BMP7,CBS,NRXN3,RAB26,HOMER3,PYGO1,KLHL3,EXOG,EDN1,FRY,AASS,SRPK3,SEMA4D,ANKFY1,RUNDC3A,GRM2,IGF1,ITGA7,LSS,MMP16,NF1,PCBP3,PDE4B,FXYD1,RFX2,KDM4B,PCDHA5,GPR161,TNS1,UCHL1,ZNF154" Drug 7502_DN CP-944629 [668990-94-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,ARNTL,CDK13,ADAM15,MYRF,IL33,CNOT8,CSF1,CTH,USP6NL,FEM1B,FCF1,FAM13A,COQ7,ETV1,ANKMY1,FER,FHL1,GLYR1,GLUL,POLL,MBNL1,MYO6,NDP,RETREG1,PTPN13,CCDC40,MRAS,PEX26,SLC14A1,BTBD7,ARHGAP26,ZBTB43,ATP10B,SH3GLB2,MPPE1" Drug 4101_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "GAS7,ST3GAL5,LARGE1,ENTPD4,ARHGEF10,VCAN,PDE4DIP,DBT,EIF4G2,COQ7,ZNF549,ETV1,MSL3,LIG4,MBD1,CLDN11,PLCD1,STRN3,MINDY2,PPP5C,WDR25,ZSCAN32,FBXW7,ANKRD6,PEX26,COA1,UNC5B,EXOC7,KIAA1107,DICER1,GPR161,SSBP2,HIRA,SEMA3B,PHTF2,AAAS" Drug 2618_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MARK4,ADGRB2,RGS11,CA4,ARHGEF1,MYRIP,HAPLN1,NCOR2,EDN1,FLNC,PRELID3A,SIGLEC8,INPP5K,ALDH1L1,KCNB1,MEF2C,ADAM22,NCF2,NF1,PGAM2,MBOAT7,POLG,MINDY2,SAMD9,PTPRD,CCDC40,RGS12,KCTD17,KLHDC8A,PREX2,KDM4B,SPTAN1,JMJD6,SYT5,WIPF1,TIGD6" Drug 335_UP nifedipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "LTBP4,ALK,BIN1,CDC42BPA,ANK2,ARNTL,ATP6V0A1,CA8,DLGAP1,CYBB,HDAC4,DBT,EPHB1,SPEG,CORO2B,FYB1,RASSF8,ATXN2L,INSM1,L1CAM,ADAM22,NF1,SLC11A2,POLG,PPP2R2B,MASP1,GAL3ST4,EMID1,RASA3,SH3GL3,ASAP3,LHPP,TAL1,TBL1X,PARD3,PLPPR2" Drug 5001_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBB2,CDC14B,DNAH17,MYRIP,NCOR2,ARHGEF4,EDN3,TNK2,ELN,CORO2B,FGF13,OGA,SRCAP,GRIK5,KCNJ5,KCNQ3,ADAM22,MX1,NF1,PCSK5,MTRF1L,PRKAR1B,FAT4,KLHL11,PNMA8A,TCP11L1,PKNOX2,SNAP25,ZC3H13,ARHGAP26,WSCD1,THRA,TNS1,SPHK2,SLC30A3,PLSCR4" Drug 7358_DN Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,AP2A2,BIN1,CDC42BPA,APLP1,APOC1,CDK13,CFLAR,C5,ARHGEF1,PLEKHB1,TAOK2,HOMER3,MFAP3L,TMCC2,CDON,EDNRA,INPP5K,GLYR1,GPD2,DHX35,KCNH2,MAP4,KITLG,AFF1,MMP16,STRN3,NEK11,EMID1,PPP4R3A,ZKSCAN3,COA1,SNCA,ELOVL4,TK2,CABIN1" Drug 605_UP monastrol; Up 200; 20uM; MCF7; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,LTBP4,BIN1,ARRB1,ARRB2,HIP1R,ARHGEF6,PCYT1B,EDNRA,FAM13A,EIF4G2,ELN,STX2,GNAO1,MCHR1,GRIN2C,PADI2,AGBL5,MAPT,KITLG,NTRK3,PDE1C,GPR173,PNMA3,PTCH1,PTPRD,CCDC40,ZFHX4,FNBP1,HECW1,CDH22,PARD3,CA14,SPHK2,TFIP11,GDPD5" Drug 6611_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADRA1D,MTUS1,BIN1,APC,SYNJ2,MYRF,HOMER3,ARMC8,CPS1,CREM,NCOR2,PDE4DIP,SUGP2,AASS,POLL,SYNPO,INPP5B,KPNA5,MAPT,AFDN,GIT1,LYRM9,NDP,FSD1,MAPK7,SBF1,ZNF821,SMARCD3,SPTAN1,EXOC7,WSCD1,GPR161,TRIO,SSBP2,ZKSCAN5,TFIP11" Drug 3678_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADD2,NME5,AMH,BACH1,BMP7,CACNA1I,RAB26,FHL5,COL9A3,CRMP1,DTNA,AASS,RGS17,ETV1,ALDH1L1,ADAM28,GFER,HPGDS,FAM107A,MAPT,MMP16,MMP17,LYRM9,STRN3,RFX2,ZSWIM8,ATP10B,SYT1,PCDHGA10,HIF3A,TNS1,TRO,ZNF24,ZNF225,KCNAB1,EPM2A" Drug 6311_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "SHROOM2,NRP2,SCAPER,CBFA2T2,ABCG1,SGSM2,IRAK4,FGFR1,DISC1,KCNMB4,ATXN2L,SYNPO,HNMT,HSF2,KIFC3,SMAD1,MIA2,MMP16,NOVA1,PFKFB2,DUSP26,PTCH1,SUGCT,NCBP3,FBXO11,WDR37,ARHGEF40,BTBD7,KIF13A,ST5,PHLDB1,FBXW11,SMG6,NT5M,KCNAB1,PHTF2" Drug 3214_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "RALGAPA1,ADD2,BIN1,ATP1A3,SEPT7,AKAP7,BAG4,VCAN,ARHGEF4,PLXNC1,FAM198B,OLFM1,AFF2,FYB1,SESN1,PRUNE2,AP4S1,KIT,MYCN,NEFM,NFIX,NOVA2,NTRK2,LRP12,ZSCAN2,ZMAT4,TCP11L1,SH3GL3,SNCA,SYT5,DOCK9,R3HDM1,WIPF1,KCNK12,NT5M,JPH3" Drug 3394_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AMPD3,BIN1,APC,APLP1,PLA2G4C,DNAH17,SCAPER,CCNT1,CLGN,STOML1,PICK1,CTH,SLC12A6,NCALD,SPEG,FGF12,OGA,RUNDC3A,RAB30,KCNJ5,KPNA5,SMAD1,MAPT,GIT1,MSI1,NF1,PLTP,PEX26,PKNOX2,SMARCD3,TSNAXIP1,DOK5,PDIA2,WIPF1,SPHK2,EVI5" Drug 3532_DN Loracarbef [121961-22-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,AP2A2,APC,APOC1,PPFIA3,CDK10,MARK4,RASL11B,BCL7A,CFLAR,SCAPER,B4GALT6,CTH,DAPK3,GIT2,EGFR,MRNIP,BAIAP2,HNMT,INPP1,MAP4,NF1,SLC25A23,PPP5C,PRKAR1B,CNNM2,KIF13A,KDM4B,TACC1,PDLIM2,FBXW11,AP4E1,SLC44A1,ZKSCAN5,UBTF,SEMA3B" Drug 6263_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBB2,EPB41L5,FAM131A,ATP6V0A1,KIF1A,CNOT8,ARMC8,DZIP3,MFAP3L,CELSR3,ANKMY1,FHL1,GNG4,GRB10,ELOVL5,HSF2,INPP5B,IPO5,MBD1,SLC11A2,SETD4,PIK3R1,MBOAT7,PPP2R2B,TMEM104,TMEM231,ZDHHC14,BTBD7,SMARCC2,UNC5B,CEP68,HIRA,ZNF24,NDRG4,REEP1,MPPE1" Drug 6288_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BRAP,BIN1,APBB2,WASF1,CA12,TBRG4,EPS15L1,PUM1,DCAF8,HDAC4,RUSC2,SPOCK3,FEM1B,FCGRT,CGREF1,ERAP1,MAP4K5,AGBL5,DHX35,MN1,TAGLN3,SLC25A23,FSD1,PRPH,ELOVL2,MCMBP,CSRNP3,FAM102A,ASAP3,PEX26,KBTBD4,BTBD7,IFT122,PDLIM2,ZMAT3,METTL3" Drug 6078_DN Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,ADRA1D,NME5,BIN1,APBA2,ATP6V0A1,RIPK1,MTMR3,CACNA1I,HOMER3,CSNK1E,PDE4DIP,DOCK4,MFAP3L,DTNA,DUSP9,STX2,DISC1,POLL,RASSF8,KPNA5,MAP4,MID1,MMP16,MPP2,NF1,MBOAT7,MAPK7,PRPH,PTN,SH3BP2,SPART,TACC1,KIAA0930,PCDHA6,TMEM121" Drug 3540_UP Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,ANK2,APBB2,SLC4A4,CFLAR,DGKI,CDH2,SLIT2,ENTPD4,CSF1R,RIMS2,DBT,EDNRA,PLXNC1,SPEG,GATM,MALT1,GNG4,GPD2,GRM8,ADAM22,LRP12,CCDC40,FAM184A,RGS12,KCTD17,NEK11,SH3BP2,ARHGEF40,PCDHGA10,TNS2,CRTC1,R3HDM1,PLPPR2,NT5M,SLC17A7" Drug 6602_DN Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "C1QTNF1,CDK13,ARHGEF1,SCARB1,CNOT8,ABCG1,CSF1,PDE4DIP,SLITRK5,ARHGEF4,TBC1D5,DYNC1I1,COQ7,RRAGB,SEPT9,SCIN,LIG4,MAP4,NFIX,CCSER2,PRKAR1B,FAT4,ZFP30,AMBRA1,ANKRD6,SMARCD3,ST5,SYT1,SMG6,SZT2,BEX4,NDRG4,NAV3,EPM2A,UBE3B,PHTF2" Drug 1698_UP Isoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADRA1D,APOC1,BACH1,SCAPER,B4GALT6,RAB28,BAG4,CRMP1,GPRASP1,SPOCK2,EDNRB,MBNL2,PLXNC1,NCALD,BAIAP2,FHL1,CGREF1,GRIK5,MAN2A2,NEK1,NF1,NFYA,CNOT4,PRKCB,ZNF821,FNDC3A,BTBD7,KIF13A,SPART,STX1A,PLCB1,ARC,FBXW11,TK2,LMF1,ZNF45" Drug 5768_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "RALGAPA1,ASPHD1,BEGAIN,APC,KIF1A,BMP7,HIP1R,CHRNA4,LY86,HOMER3,MFAP3L,EDNRB,PLXNC1,PIPOX,FOXF2,ERGIC3,SRCAP,POLL,ADAMTS13,CACFD1,GSTM5,KCNB1,KIFC3,SHC3,AFDN,PDE4A,ABCB1,DIRAS2,PID1,RGS3,TCP11L1,STUM,RASA3,SLA,SEMA3B,DPF3" Drug 3466_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBA2,ARHGDIG,CFLAR,GYG2,HIP1R,PLEKHB1,IQCK,SLC4A8,SH2B1,EXOG,ELN,ZNF589,GPER1,IL6ST,ITPKB,KPNA5,MATK,PLCB2,PMP22,FAM184A,RGS12,EMID1,SH3BP2,ASAP3,SMARCD3,ZHX3,PHLDB1,VPS13A,PLCB1,EXOC7,PCDHA6,CHST8,ZNF34,SLC44A1,GDPD5,EPM2A" Drug 6930_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MADD,NUMB,KIF1A,BACH1,MPDZ,CFLAR,SYNJ2,FOXN3,RAB28,CLCN3,CREM,CSNK1E,ZNF337,PHF20L1,EIF5,VPS13B,CGREF1,SLC2A6,ATXN2L,AGBL5,OGG1,POLG,PRODH,RIPOR1,HSPA4L,AMBRA1,PDZRN3,ERC1,SEPT8,DIP2A,TRIO,REEP1,ZNF184,HPS4,PCBP4,JMJD1C" Drug 6252_UP Hexestrol [84-16-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AMPD3,AMT,APBB2,CAMK2B,TPP1,VAX2,CREM,HAPLN1,CRY2,CSF1R,DBT,JAKMIP2,RCAN1,DTNA,CNNM1,MBNL2,EGR3,PLXNC1,ENO2,PIPOX,FLNC,B4GALNT1,MALT1,GRB10,IL6ST,INPP1,KHK,NPR2,SAMD9,PTX3,C1orf54,SGK1,TSPYL2,SLC44A1,TPM1,UBE3B" Drug 2974_DN Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,AP2A2,CFLAR,SYNJ2,SGCE,CAMK2G,CLGN,IQCK,PDE4DIP,PPP6R2,RUSC2,SGSM2,STX2,CD320,FCGRT,ZNF589,FER,FGFR1,PDLIM5,INPP5K,SRCAP,ADAM28,DIDO1,ELOVL5,ITGA7,MAP4,OGG1,RPS6KA2,SH3BP2,FBXO11,KDM4C,KAT6B,ZKSCAN5,FLRT2,TRIM9,KCNAB1" Drug 4461_DN fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,CDC42BPA,APLP1,SCARB1,ARMC8,SLITRK5,PHF14,FAM131B,DCAF8,HIPK3,ZNF589,PDLIM5,TRAF3IP2,GLYR1,SCIN,IL12A,INPP5B,JAK2,LSS,MBD1,MEF2C,KITLG,NFYA,ZNF821,SH3BP2,ASAP3,SMARCA4,SPTB,CEP68,WSCD1,ZEB1,GPR161,TNS1,TRPM2,TFIP11,PHTF2" Drug 2984_DN Liothyronine [6893-02-3]; Down 200; 6.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,APAF1,CDK10,CASK,NCOA1,SYNJ2,CAPN3,SOCS6,BAG4,B3GAT3,C2CD2L,CDON,DTNA,MBNL2,C3orf18,TUBD1,PTK2B,CAMKK2,SLC2A6,NCKAP1L,MAPT,PLCB2,PTCH1,ZSCAN32,KHDRBS2,SH3BP2,SNAP25,SPTAN1,RGL1,EXOC7,TBL1X,DMXL2,TPM1,SMUG1,UBTF,PHTF2" Drug 2992_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "RALGAPA1,AMH,ANK2,BMP7,CACNA2D2,SEC31B,CREM,RGS6,PDE4DIP,DZIP3,EXOG,EDN3,SRPK3,NEU3,GFER,SPACA9,AFDN,MMP16,MSI1,ADAM22,MYCN,OXTR,PILRA,RELN,CNNM2,RGS12,NEK11,CPEB3,LHPP,ELOVL4,TPM1,FLRT2,CLIP2,KLC2,KCNK12,SLC17A7" Drug 5514_DN Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "SRPX,CASK,NCOA1,SLC4A4,CFLAR,SPAG9,IQCK,NECTIN3,SOCS5,DOCK4,DCAF8,DBT,KIAA0753,FHL1,MALT1,MIA2,GIT1,NF1,FA2H,FSD1,RGS3,TRAPPC13,PREX2,FAM214B,CDK5RAP2,TSPYL2,ELOVL4,NSFL1C,TACC1,TRIM2,PARD3,METTL3,HIRA,TFIP11,MPPE1,RNF170" Drug 3382_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,AP2A2,CACNA1I,RHBDL1,ARHGEF2,SULT4A1,CNTFR,CNTN1,CRYM,SNCAIP,CSF1R,FAM169A,DAPK3,RUSC2,TMCC2,FRY,MTSS1L,DISC1,GRB10,GRIK5,GUCY1B1,KIF5A,MAN2A2,TAGLN3,MYO7A,NOVA2,PTPRH,CCDC40,RPS6KA2,SMPD3,HECW1,SPP1,SZT2,HIF3A,R3HDM1,FLRT2" Drug 2475_UP Benperidol [2062-84-2]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "RALGAPA1,PKP4,BCAS1,ATP1A3,MYOM1,CFAP410,SLC16A4,CDH2,CDO1,CLGN,B4GALT6,TAOK2,STOML1,SULT4A1,HOMER3,ABCG1,DCAF4,ARHGAP24,HEYL,OPTN,MBNL2,RASGRP2,AGAP2,FLNC,IL6ST,NPR2,CCSER2,GDPD2,WDR25,CCDC40,PKNOX2,SNAP25,PEG10,SYT5,VSNL1,KCNAB1" Drug 1181_DN 2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "OSBPL1A,KCNAB2,CAMK2G,CD38,HOMER3,C2CD2,CREM,CSF1R,RUBCN,NR1D2,DPH1,EIF4G1,COQ7,RASGRP2,PTK2B,POLR1B,TMEM164,SEMA4D,GRB10,DIDO1,BTN2A1,LSS,MBD1,PPP3CC,GTDC1,EXD2,CASC3,PEX26,ARFGAP1,TEX2,CLASP2,KAT6B,UBTF,VAV1,XRCC4,EPM2A" Drug 7482_UP Acetohexamide [968-81-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,SEMA6A,LTBP4,AMPD3,SEMA4G,KIF1A,ARHGEF2,CSF1R,DBN1,CELSR3,ING4,TPK1,SRCAP,RAB30,ADAMTS13,TJAP1,MAP4,MPP2,ADAM22,LYRM9,NOVA2,MTRF1L,LRRN3,WDR25,SEC14L1,ZNF821,LIMCH1,MAPKBP1,SNCA,USP33,HECW1,ELOVL4,TRIO,CLIP2,ZNF45,SEMA3B" Drug 3444_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,NCOA1,CBR1,CLCN3,BAG4,CRY2,FAM169A,CTH,DCAF8,EIF5,EZH1,RAB30,MSL3,BTN2A1,ATXN2L,ADAM22,CNOT4,RETREG2,FA2H,ELOVL2,NKAIN1,NEK11,ZC3H14,FBXO11,KDM4B,POGZ,SS18,PLCB1,SATB2,TRIM2,TMPO,PARD3,HSPBP1,CLDND1,SMIM8,PHTF2" Drug 5759_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,ADD2,APBB2,EPB41L5,PRX,ARRB1,BMP7,ST3GAL5,MTMR3,CACNA1I,CACNA2D2,NRXN3,CNTFR,WHRN,CREM,PDE4DIP,BRINP1,RGS17,ST3GAL6,FGFR1,HPCAL4,PCDH17,ADAM22,MT1M,TAGLN3,MYO7A,PDE4D,ZSCAN32,ACSS3,TCP11L1,SEMA6D,SH3BP2,HECW1,PLCB1,PCDHGA10,PIK3R5" Drug 5633_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADD2,C1QTNF3,AMPD3,SEMA7A,APAF1,CDC14B,ALDH7A1,WHRN,CPS1,NCOR2,CRYM,RASGRP2,ETV1,HPCAL4,GNAO1,KCNH2,MSI1,MX1,NOVA2,PURG,CNNM2,PTPRB,MARCH1,C1orf54,KCTD17,SP4,PEG10,SSTR2,RGL1,RPGRIP1L,SLC44A1,UBE3A,SPHK2,SLC30A3,DNALI1,DPF3" Drug 1887_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADORA1,PKP4,SEMA4G,NUMB,CNOT8,CNTFR,CDC42BPB,DAPK1,RUSC2,C2CD2L,DPYSL2,TNK2,FGFR1,SCARA3,TRMO,SMC2,ATP2C1,TMEM8B,CRCP,PRRC2B,KTN1,NELL2,TRHDE,PRKACB,MAPK7,ACSS3,NUDT11,KDM4D,ARHGEF40,OBSL1,TK2,UBE3A,LMF1,WNT7A,MAP3K12,SLC17A7" Drug 2880_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APOC1,ADAM23,GYG2,CAMK2B,CCNT1,PICK1,CNTN1,CSNK1E,VCAN,RUSC2,DTNB,ELN,HSD17B14,ERBB2,ERCC2,FGFR3,PDLIM5,ALDH1L1,PCDH17,ICA1,ITGAM,CDK18,TMOD2,SLC25A23,MAPK7,SNRK,RASA3,SLC11A1,SPTB,PHLDB1,JMJD6,ARC,DNMBP,SLC44A1,VSNL1,GDPD5" Drug 3931_DN Benfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,AMPD3,FAM131A,CDC14B,DNAH17,CPS1,SH2B1,CSF1,CDON,SUGP2,EGFR,EZH1,DLC1,FGFR3,OGA,DISC1,SEPT9,GPER1,GRIK5,CACFD1,GSTM5,DHX35,KCNJ5,KCNN1,GIT1,ZNF862,NEK1,PDE4A,RETREG1,NLGN1,SLC6A8,CXXC4,PEG10,ATP10B,PHLDB1,VPS13A" Drug 2445_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MTUS1,SYT13,CDC42BPA,APBB2,CDC14B,PLA2G4C,DNAH17,KIF1A,FUBP1,CSF1,DZIP3,RIPOR2,SPOCK3,CDON,DTNB,MAMLD1,APC2,NSG1,GFER,RUNDC3A,SOX21,KCNJ5,KIT,AFDN,MSI1,MYO6,OGG1,NECAB2,RFX2,RGS4,MAP6D1,FERMT1,SLC11A1,ZC3H13,ATP10B,PLSCR4" Drug 4079_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBB2,MARK4,SLC4A4,ADAM23,MPDZ,SYNJ1,CACNA1I,CFAP410,CACNA1A,AKAP7,ARHGEF10,PPP6R2,DLC1,FGF1,SCARA3,SYT17,TDRKH,LPAR4,ACOT7,LMO2,MIA2,TAGLN3,P2RY1,WDR25,ZSCAN2,ASAP3,LHPP,THSD1,PCDHA5,TNS1,TRIO,OSBP2,WIPF1,LAT2,NPDC1,NT5M" Drug 1542_UP Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NME5,CDC42BPA,CDC14B,MARK4,SYNJ2,CAMK2B,CBFA2T2,SLIT2,WHRN,RIMS2,KIAA0586,SPOCK2,MFAP3L,IGSF6,PRELID3A,POLL,MUM1,IL6ST,INPP5B,LMO2,ZNF862,NPY,PPP5C,PRODH,GDPD2,ZSCAN2,ASAP3,SLC2A5,COA1,RBM34,STX1A,KIAA1107,TRIM2,SZT2,CRTC1,UPF3A" Drug 6216_DN Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MTUS1,OSBPL1A,SPOP,AMPD2,MPDZ,CFLAR,ARHGEF7,KRIT1,ENTPD6,CSNK1E,SOCS5,ZNF337,GIT2,PARD6A,MED12,NR1D2,EZH1,GAA,MAPT,MMP16,GIT1,NLE1,FSD1,PTK2,TCP11L1,FAM102A,KIF16B,TMCC1,DNMBP,SIK3,TIAM1,TRIO,CLDND1,SPHK2,PCBP4,MARCH8" Drug 2915_DN Ethamsylate [2624-44-4]; Down 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APAF1,APBB2,CFLAR,CD86,ARHGEF1,SRSF11,TPP1,CLOCK,RNF14,VCAN,DCAF8,DTNA,PCOLCE2,SH3YL1,ACSL4,ZNF589,FECH,SEC23B,OGA,LIG4,MIA2,CNOT4,OGG1,OPA1,CCSER2,GPSM2,SMOX,EXD2,KBTBD4,SS18,ATMIN,PARD3,ZNF32,ZNF184,MARCH8,PHTF2" Drug 4009_DN Sulmazole [73384-60-8]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NME5,GAS7,PDE8B,ATP2A2,ALDH7A1,SYNJ2,HOMER3,RUSC2,CDON,CNNM1,MRNIP,COQ7,ETV1,GRM8,SHISAL1,LIFR,LMO2,MBD1,NDP,PDE4D,PLCD1,PPP5C,KHDRBS2,RGS4,AMBRA1,FNDC3A,ARHGEF40,SLC9A5,SS18,ELOVL4,ARC,RPGRIP1L,SYNE1,DNAH7,CABIN1,NT5M" Drug 2354_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "KCNAB2,GAS7,CDK10,ARRB2,MARCH3,NCOA1,CFLAR,CAPN3,CAST,CSF1R,DCAF8,MAML1,DBT,NR1D2,DTNA,TNK2,EZH1,ZNF589,PCYOX1,FAM49B,TPK1,SEPT9,HSF2,IL6R,ITPKB,CNOT4,PPP3CC,C1orf54,TRAPPC13,PEX26,SLC12A2,ZKSCAN3,TLR4,ZNF32,EPM2A,NLRP3" Drug 5317_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASPHD1,ABHD6,APAF1,FAM131A,ALDH7A1,KIF1A,ST3GAL5,CFAP410,CARS,FAM189A2,ENTPD4,CSF1R,PDE4DIP,CTH,CNNM1,EGFR,HSD17B14,ANKMY1,GALC,POLL,ICA1,LSS,MAP4,MAPT,MPP2,NFYA,PPP2R2B,PRODH,CNNM2,KDM4C,NXT2,PHLDB1,ZNF34,CABIN1,VIPR2,MAP3K12" Drug 2836_UP Benperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,CDC14B,PLA2G4C,CFLAR,RAB29,CA12,ARHGEF2,FOXN3,GREB1,NCALD,OGA,GAD1,SYT17,SRCAP,GSN,SLC2A6,IRAK3,ELOVL5,IL6ST,MITF,AFDN,ZNF862,PCBP3,NTRK2,PRKAR1B,RGS12,RASA3,DZIP1,PEX26,ZBTB43,CRTC1,SLC35G2,DICER1,ICAM5,WIPF1,KCNAB1" Drug 6226_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "OSBPL1A,CDC42BPA,MTMR2,PTBP2,KRIT1,SCARB1,SYNGR3,SRSF11,COL4A5,SMARCAL1,DCAF8,GIT2,EXOG,MRNIP,SEMA4D,TRMO,MALT1,IL6ST,MAPT,MIA2,GIT1,NFYA,PDE4A,PMP22,MBOAT7,TMEM231,RPS6KA2,BTBD3,MAPKBP1,POGZ,SS18,CEP68,MCF2L,BEX4,FTSJ1,ACTR3B" Drug 7529_UP Suramin sodium salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,SEMA4G,KYAT1,SCARB1,PICK1,CREM,CNNM1,EGFR,CDKL3,ZNF589,BAIAP2,PDLIM5,POLL,BTN2A1,SCIN,KCNJ5,LIG4,MIA2,MPP2,NFYA,PCDHGC3,KCTD17,SIRT2,BTBD7,ARFGAP1,CDK5RAP2,FNBP1,KDM4C,LHPP,TROVE2,DIP2A,COBL,GPR161,EVI5,EPM2A,SMIM8" Drug 7533_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADRA1D,ALCAM,LTBP4,APAF1,PDE8B,SCAPER,CA4,CSF1R,PDE4DIP,DOCK4,EDNRA,HEYL,CDKL3,FGFR3,ALDH1L1,ATXN2L,HNMT,KCNQ3,KPNA5,MAPT,MATK,ZNF862,NFYA,CNOT4,NLE1,MAPK7,ASAP3,KDM4C,CLASP2,CEP68,JMJD6,IQCE,TCF4,PCDHA5,TRIO,SMIM8" Drug 6960_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,AK2,RIPK1,SRSF11,ARMC8,CREM,ABCG1,DAPK3,DBT,FBXL5,FCF1,POLR1B,FHL1,EFCAB2,CINP,CNTRL,KCNF1,MAP4,LYRM9,NPR2,SAMD9,ELOVL2,RAD51D,SAFB,SH3BP2,SYBU,ABLIM3,ZKSCAN3,LHPP,ARC,SYT1,ANKRD12,EXOC7,METTL3,VGF,VIPR2" Drug 7064_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBB2,BMP7,SGCE,ARHGAP33,SRSF11,SOCS6,HDAC4,DTNA,RASGRP1,MBNL2,EGR3,DENND4A,EFCAB2,GPD2,INPP5B,KTN1,MATK,MMP16,ZNF862,NF1,NFYA,PIK3R1,LRP12,POLG,PPP5C,ELOVL2,PTK2,FNDC3A,CEP68,MTCL1,AGTPBP1,RPGRIP1L,TCF12,TRIO,VGF,ZBTB14" Drug 5606_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBA2,APBB2,GAS7,EIF4G3,CFLAR,SCAPER,TAOK2,STOML1,AKAP7,CRY2,PDE4DIP,MBNL2,STX2,KAT8,FGFR1,SEMA4D,CGREF1,RASSF8,HNMT,KCNH2,TM6SF1,MIA2,ZNF862,LRP12,FSD1,RGS12,SUPT20H,BTBD7,KDM4C,ZBTB43,ELOVL4,PLCB1,FAM155A,XRCC4,SLC17A7,SENP7" Drug 3355_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,LTBP4,CACNA1A,CAMK2B,NCOR2,DZIP3,RIMS2,SPOCK2,BRINP1,HIPK3,ETV1,SCML2,ZNF589,FHL1,ADAMTS13,GRM2,IRF8,MMP17,TAGLN3,MYCN,NEK1,LRP12,CEP41,MAPK7,CCDC40,TRIM68,EMID1,KCNIP1,ASAP3,ZC3H13,SPTB,ATP10B,JMJD6,EXOC7,GPR161,TNS1" Drug 7390_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,APBB2,CASK,MARK4,ARHGEF1,ARHGEF2,CLCN3,HOMER3,RCHY1,BAG4,NECTIN3,DZIP3,KLHL3,CDON,EDNRA,FEM1B,FCF1,MFSD10,MAN1B1,SYNPO,INPP5B,KIF2A,SCAMP5,NF1,PFKFB2,ZNF671,SBF1,SCN8A,SH3BGR,NUBPL,BTBD7,SLC22A4,NXT2,TRIM2,MAP3K12,SMIM8" Drug 2954_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADD2,AMPD3,SYNGR3,SULT4A1,CREM,ABCG1,SPOCK3,ALDH1L1,SRCAP,KCNMB4,PCLO,TPPP,MAN1B1,LAMA2,SHC3,MGAT3,AFDN,MMP16,GIT1,CNOT4,OPRL1,PCDH9,PFKFB2,SERPINI1,POU6F1,PRKAR1B,BCAS3,MRAS,SLC11A1,CXXC4,ZHX3,IZUMO4,SPTB,SYNE2,SLC44A1,FAM155A" Drug 2558_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,BIN1,APC,CDK13,PDE8B,C5,CAMK2G,HOMER3,CPS1,CREM,CELSR3,SUGP2,MTSS1L,DLC1,EFCAB2,OGA,SEPT9,POLL,SPACA9,LSS,AFDN,ZNF862,SETD4,ENPP2,PLEC,SEC14L1,MRAS,SH3BP2,CNKSR2,DBNDD2,SPTAN1,PDLIM2,DMXL2,CHST8,REEP1,FAM13C" Drug 2909_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG3,NDRG2,GAS7,MARK4,C5,ARHGEF1,SCARB1,PPP1R16B,ING4,EIF1,COQ7,ANKMY1,F8,SCML2,FGFR1,FLT1,USP19,KPNA5,MAP4,CCSER2,RETREG1,ZNF426,PRKAB2,ZCWPW1,PLPPR3,SBF1,PPM1E,DZIP1,PEX26,MAPKBP1,STX1A,AP4E1,TNS1,PLPPR2,URM1,NLRP3" Drug 7208_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASPHD1,MADD,EIF4G3,QKI,SIPA1L1,PDE4DIP,PPP6R2,KIAA0753,DMPK,EPB41L2,SEMA4D,ZNF276,KCNMB4,GRB10,DHX35,INPP5B,MAP4,SETD4,SLC25A23,RIPOR1,RXRA,EPN2,ERC1,ZBTB43,POGZ,ELOVL4,CEP68,EXOC7,CABIN1,SSBP2,RPRM,UBTF,LMF1,XRCC4,ZNF189,ACTR3B" Drug 2191_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,APBB2,APOC1,CDK10,SEMA4G,PDE8B,DNAH17,PTCH2,ADGRB1,MAGI1,CACNA2D2,TAOK2,COL4A5,SIPA1L1,DBT,TNK2,FER,IQCG,DLL3,KCNQ3,KHK,NNAT,PLEC,EPB41L4B,BEND5,RYR3,SEMA6D,PEG10,SPTB,LHPP,TBCEL,TCF4,RPGRIP1L,TNS2,SLC35G2,SPHK2" Drug 4802_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADORA1,C1QTNF1,BEGAIN,APC,ARNTL,ALDH7A1,CFLAR,CACNA1I,CALB2,SCARB1,ARHGEF2,SEPT7,TPP1,AKAP7,NCOR1,GREB1,EGR3,ELN,ANKMY1,ZNF589,FHL1,POLL,GRIK5,INPP5B,KCNH2,KCNN1,MMP16,NF1,C1orf54,TCP11L1,SYBU,PKNOX2,EXOC7,WSCD1,CLDND1,SLC30A3" Drug 2059_DN Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BRAP,MTUS1,AMT,APOC1,MTMR3,QKI,WHRN,CSNK1G3,SNPH,ZFYVE16,SGSM2,ENO2,USP21,TPK1,FYN,INPP5K,ZNF276,PCLO,ICA1,TJAP1,MIA2,MINDY2,HSPA4L,ST6GAL1,FAM214B,KBTBD4,KDM4B,KDM4C,TSPYL2,CAMTA2,SATB2,CLASP1,TRIO,KLC2,TFIP11,PLSCR4" Drug 5201_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,AP2A2,ARRB2,CFLAR,AP4M1,SLIT2,DTNA,SUGP2,EGFR,FGFR1,BAIAP2,ANKFY1,OGA,GALC,GNG4,GPD2,TDRKH,ATXN2L,INPP5B,KCNF1,ADAM22,NF1,NFYA,SLC11A2,MAPK7,KLK6,RIPOR1,SH3BP2,ZHX3,ZSWIM8,TROVE2,PCDHA6,AP4E1,TK2,CDK20,VGF" Drug 4588_DN Vitexin [3681-93-4]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NME5,ATP1A3,NRP2,SCAPER,SYNGR3,WHRN,PPP6R2,CDON,DTNA,DUSP9,EDIL3,CELSR3,ETV1,OGA,ELOVL5,SYNPO,CNOT4,SLC11A2,CLDN11,STRN3,FA2H,PRPH,ZSCAN32,ZNF821,AMBRA1,PDZD2,LHPP,POGZ,SAMSN1,TCF4,CHST8,TNS1,VGF,XRCC4,SMIM8,PHTF2" Drug 5732_UP Sulfameter [651-06-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "SYN3,TRMT9B,CDC42BPA,BACH1,ADGRB2,BMP7,ST3GAL5,CACNA1I,CA12,RUNX1T1,CDO1,CREM,NCOR2,RGS6,PLXNC1,OLFM1,HPCAL4,COPS8,ADAMTS13,NEFH,NF1,PCSK1,PDE4D,PPP5C,ACSS3,C1orf54,PKNOX2,MYO16,TSNAXIP1,ZSWIM8,SPP1,POGZ,HIF3A,ICAM5,PIK3R5,RPRM" Drug 2765_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC14B,NCOA1,ATP6V0A1,RIPK1,CBFA2T2,SCARB1,CNOT8,FAM189A2,CREM,PDE4DIP,PPP6R2,IRAK4,ZNF589,FGFR1,DISC1,GLYR1,RAB30,CACFD1,KCNH2,LSS,MITF,ZNF862,NEK1,NLE1,RNASEL,PPM1E,EPN2,UNC5B,STX1A,VPS13A,CLDND1,ZNF24,TFIP11,EVI5,MPPE1,PHTF2" Drug 3199_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,TRMT9B,BCAS1,SEMA4G,SLC4A4,CFLAR,SYNJ2,CAMK2G,FAM189A2,ARMC8,BAG4,CSF1R,FAM169A,ARHGEF4,CYBB,DTNA,STX2,GAA,LPAR4,KCNH2,PCDH9,NLE1,RIPOR1,CEP97,RGS12,INTS9,KIF13A,ANKRD12,DOCK9,ZNF34,THRA,HIRA,PLPPR2,VIPR2,ST7,TIGD6" Drug 6999_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,CDC42BPA,APBB2,CDK10,CDK13,CFLAR,AP4M1,HOMER3,DCAF8,DAPK3,MFAP3L,DTNA,FEM1B,RGS17,KAT8,FAM49B,CGREF1,GALC,TXNL4A,GNG4,GRB10,KITLG,STRN3,POLG,PPP2R2B,PPP5C,RIC8B,ELMO2,MAPKBP1,ZHX3,EXOC7,CABIN1,UBTF,VGF,VIPR2,ZBTB38" Drug 3566_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,APBB2,RIPK1,CFLAR,SULT4A1,PDE4DIP,GIT2,MFAP3L,EDNRA,EZH1,SYT17,PRRC2B,ICA1,KHK,MAP4,NPR2,PPP3CC,PRKAR1B,PTPRE,NKAIN1,SH3BP2,EPN2,SLC6A8,CCDC88A,LIMCH1,ZHX3,THSD1,TTBK2,SMG6,RPGRIP1L,TK2,CABIN1,RPRM,LMF1,ZBTB14,GAN" Drug 2620_UP Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADGRF5,FAM135A,TRMT9B,SLC4A4,N4BP2L1,LDLRAD4,CA4,HIP1R,CSF1,DMPK,MTSS1L,AHDC1,GFER,PCDH17,CACFD1,IRAK3,KIFC3,MSR1,ZNF862,NPR2,NTRK2,PURG,MINDY2,MAPK7,ZNF493,PNMA8A,FRMPD1,FAM214B,PKNOX2,SPTAN1,RGL1,PHLDB1,TK2,UBE3A,ITM2C,PHTF2" Drug 313_UP NU1025; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BIN1,KCNAB2,GAS7,ARRB1,ARRB2,ATP6V0A1,MTMR2,CFAP410,CAST,CD38,CSF1,ING4,TNK2,ERCC2,TRMO,CYP46A1,MALT1,RUNDC3A,TXNL4A,GRM2,NXPH3,KIF2A,ADAM22,MYO7A,FXYD1,WDR25,ATXN2,ABLIM3,KDM4B,NMNAT2,UNC5B,SPTB,UGT8,LMF1,ZNF23,GJC2" Drug 5236_DN LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "MTMR2,CAMK2G,SLIT2,NCOR1,USP6NL,DAPK3,GIT2,MFAP3L,C2CD2L,MAMLD1,EZH1,FAM49B,DISC1,SRCAP,GFER,GNG4,TDRKH,CACFD1,IL6R,KCNH2,MAPT,MPP2,GIT1,FSD1,ELOVL2,RIPOR1,FAM184A,EPN2,BTBD7,LHPP,THSD1,CHST8,TRIO,FTSJ1,SEMA3B,SMIM8" Drug 1608_UP Probucol [23288-49-5]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,ADRB2,AMT,APBB2,ARNTL,MARK4,SYNJ2,CA12,P2RX6,CD86,PPP1R16B,DBN1,C2CD2L,DNM1,ENO2,DIDO1,GSTM5,TJAP1,ITGAM,KCNN1,MAP4,MBNL1,PLCB2,SMOX,LRP12,PTK2,TCP11L1,FAM192A,SLC2A5,SLC6A8,KDM4B,SPP1,ZC3H13,THSD1,SZT2,MPPE1" Drug 3832_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,ADRA1D,MARK4,NUMB,KIF1A,BCL7A,ARHGAP33,RCBTB2,CNOT8,CSF1,RIMS2,USP6NL,JAKMIP2,MRNIP,RRAGB,TPK1,INPP5B,ADAM22,SLC11A2,OGG1,RETREG1,PLEC,PLXNB1,MBOAT7,PPP2R2B,PRPH,SNRK,ZSCAN2,CCDC25,SBF1,SH3BP2,ARHGAP26,STX1A,KIAA1107,KCNK12,ST7" Drug 1842_UP Allantoin [97-59-6]; Up 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APC,CFLAR,CFAP410,CBFA2T2,FOXN3,TPP1,SULT4A1,CRMP1,PDE4DIP,DGKG,KIAA0753,EGR3,FAM49B,SRCAP,PCDH17,COPS8,POLL,CACFD1,TJAP1,LIG4,MEF2C,MIA2,NEFH,NF1,PTPRN2,RET,GSTCD,TCP11L1,RXRA,DBNDD2,TSPYL2,TACC1,CUX2,WBP2,XRCC4,REEP1" Drug 5262_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,SPARCL1,ADAM23,SYNJ2,CAMK2B,CACNA2D2,NCOR2,ARHGEF10,TMCC2,DMPK,DTNA,DTNB,VPS13B,PTK2B,DISC1,ALDH1L1,GLYR1,POLL,STON1,SHISAL1,TJAP1,MYT1,PDE1C,CARF,ASAP3,CPEB3,SLC2A5,HECW1,RBM26,EXOC7,ZEB1,TRIM2,PARD3,CHST5,FAM155A,PARP11" Drug 458_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BIN1,APAF1,ARNTL,ADGRB2,RAB29,OSBPL3,STX2,TBC1D16,BAIAP2,SEC23B,SMC2,FYN,INPP5K,GNAO1,AFF1,TAGLN3,NELL2,SNX10,CNNM2,RBBP6,ATXN2,GALNT10,ASAP3,SMARCC2,MAPKBP1,COBL,WSCD1,ZEB1,OBSL1,GPR161,BEX4,TRPS1,TSN,SSBP2,TST,NPDC1" Drug 3988_UP Cinchonine [118-10-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADD2,AP2A2,PPP4R4,CDK13,NRP2,CAPN3,KRIT1,CHGB,LY86,AKAP5,DCAF4,SPOCK2,DTNB,EDNRA,NRN1,STON1,MAN2A2,MATN3,MIA2,NTRK3,LRRN3,PSD,PTPRB,PTPRN2,RFX2,RPS20,SEMA6D,OGDHL,SNCA,KIF13A,TACR1,EXOC7,TRIO,VIPR2,ZNF24,MAP3K12" Drug 3299_DN Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,AMT,APOC1,PPFIA3,MARK4,CFLAR,GYG2,B4GALT6,FAM189A2,CSNK1E,MAML1,GIT2,LYPD1,ACSL4,FGFR1,GPER1,CACFD1,ICA1,LIG4,MPP2,GIT1,NEK1,NF1,LRP12,PPP3CC,TMEM104,SH3BP2,AMBRA1,BTBD7,UNC5B,STX1A,VPS13A,TACC1,TK2,EMSY,PCBP4" Drug 3176_DN Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABR,AP2A2,LTBP4,APAF1,APC,PPFIA3,MARCH3,KYAT1,RAB28,COL4A5,AKAP12,SOCS5,GIT2,CELSR3,SUGP2,ENO2,BAIAP2,FYN,SEPT9,COPS8,MSL3,PADI2,HNMT,ITPKB,KCNH2,NFYA,SLC25A23,FNDC3A,KIF13A,EXOC7,IQCE,TBL1X,CRTC1,HIRA,LMF1,ZBTB14" Drug 4666_DN Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "PPFIA4,ATP1A3,RAB28,SH2B1,PDE4DIP,SGSM2,DTNA,EDN1,EDNRA,MTSS1L,DENND4A,CDKL3,ST3GAL6,FER,TJAP1,KIF2A,MAPT,MMP16,MX1,NF1,CNOT4,PLCD1,MAPK7,ELOVL2,TMEM231,ZCWPW1,MCMBP,FNDC3A,ZNF667,ARHGAP26,LHPP,ASTN2,FBXW11,THRA,TIAM1,WIPF1" Drug 1857_DN Sulindac [38194-50-2]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADORA2A,GAS7,N4BP2L1,BCL7A,KRIT1,CNOT8,HOMER3,CREM,CRY2,PPP1R16B,DOCK4,DTNA,FAM13A,PLXNC1,PTK2B,FECH,CINP,OGA,TRAF3IP2,MSL3,SLC2A6,HSF2,IRF8,ITGAM,ZNF862,SCP2,FERMT1,ZKSCAN3,SP2,TTBK2,EXOC7,METTL3,PLPPR2,XRCC4,EPM2A,PHTF2" Drug 1776_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; HL60; HG-U133A" Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,AMT,ANK2,APOC1,CDK10,PDE8B,GYG2,CA12,SPAG9,APH1A,TRMO,NSG1,RUNDC3A,ADAMTS13,PADI2,NXPH3,TJAP1,NTRK3,SETD4,PALM,POLG,BCAS3,CCDC40,CRTAC1,TCP11L1,ATXN2,ELMO2,SNAP25,UNC5B,TBL1X,KAT6B,ATP6V0E2,ZNF142,REEP1,LAMP5,URM1" Drug 3183_DN "Methylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,ALCAM,DOC2A,TRMT9B,CDK10,ATP2A2,CFLAR,SYNJ2,SCAPER,CFAP410,SOCS6,FAM169A,DCAF8,CNNM1,OPTN,EIF5,BAIAP2,SEMA4D,ZNF44,TRAF3IP2,ERAP1,COPS8,MAP4,OGG1,MAPK7,ZCWPW1,GTDC1,RGS3,PPP4R3A,KIF13A,ZBTB43,STX1A,SLC44A1,CABIN1,ZKSCAN5,HIRA" Drug 4594_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "KCNAB2,SLC4A4,ADGRB2,CACNA1A,ARHGAP33,CSF1R,RUSC2,DMPK,TNK2,SPEG,OGA,ATXN2L,FAM69A,KIF2A,MMP16,GIT1,MX1,NPR2,POLG,MAPK7,SAMD9,ELOVL2,RXRA,ZNF821,AMBRA1,DZIP1,LIMS2,SLC14A1,KIAA1107,CHST8,TNS1,UBTF,VGF,VIPR2,CLIP2,EVI5" Drug 335_DN nifedipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ADCY6,MTMR2,ARHGAP33,CRHBP,ARHGEF10,PDE4DIP,INTS1,CALCRL,FHL1,FOLR2,KHDRBS3,MPP6,TMEM8B,NEU3,LILRA2,GRIN2C,BTN2A1,HLF,IGF1,KHK,MAPT,MBOAT7,CRTAC1,SATB1,SH3BP2,FERMT1,PPP4R3A,SLC9A5,KDM4B,SPART,SSTR2,TRIM2,CDH22,TUBB1,WNT7A,MPPE1" Drug 1886_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; PC3; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "C1QTNF1,BIN1,AMT,KCNAB2,MTMR2,CAMK2B,SOCS6,CHN2,FAM189A2,FAM169A,RUSC2,C2CD2L,DTNA,PLEKHA1,TMEM8B,DISC1,CRCP,GSTM5,GUCY1A1,NXPH3,KCNB1,CLDN11,ZNF426,MAPK7,CNNM2,FAM102A,ANKRD6,ARHGEF40,SLC11A1,KDM4B,LMF1,VSNL1,CLIP2,WNT7A,XRCC4,ZNF24" Drug 6952_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AK2,PPFIA3,MARK4,RIPK1,MPDZ,BCL7A,CFLAR,C5,LHX2,HOMER3,CREM,CRY2,HINFP,LYPD1,MRNIP,CDKL3,VPS26C,FHL1,ZNF276,HTATSF1,POLL,GPR37,CNTRL,GRM8,ATXN2L,HSF2,KHK,MGAT3,NEK1,NF1,SLC11A2,PCDH9,SLC25A23,SAMD9,RGS3,IQCE" Drug 1824_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "APBB2,CDC14B,CASK,CA12,RCBTB2,SOCS6,CLTB,QKI,PREPL,CREM,TPK1,ATP2C1,HTATSF1,GPR37,BTN2A1,HNMT,IPO5,ZFYVE21,NLE1,TRHDE,FSD1,FAT4,RBBP6,ARHGAP26,SAMSN1,SS18,ELOVL4,CEP68,SIN3B,SATB2,TRIM2,TNS2,XRCC4,EVI5,PLSCR4,AAAS" Drug 2521_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG2,AMPD3,CDC42BPA,EP400,ZBTB10,STX16,SCAPER,C5,BAG4,CSNK1E,SIPA1L1,SLITRK5,PPP6R2,DTNA,MTSS1L,ST3GAL6,SEPT9,POLL,LILRA2,CACFD1,LIG4,MAP4,GIT1,N6AMT1,ZNF862,ENPP2,PLCB2,MSANTD2,SGK1,ARHGEF40,SLC12A2,SNCA,TROVE2,PDLIM2,PLPPR2,SH3GLB2" Drug 1055_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASPHD1,NUMB,RAB26,PPP6R2,TBC1D5,GIT2,USPL1,STX2,VPS26C,KAT8,B4GALNT1,ZNF276,KCNMB4,GRB10,IL6ST,MAP4,MPP2,N6AMT1,NCAM2,NEK1,NF1,PPP5C,MAPK3,FBXW7,TCP11L1,SUPT20H,ZNF430,SP2,ZBTB43,CAMTA2,SS18,NXT2,ELOVL4,NSFL1C,TBL1X,ZBTB14" Drug 704_DN "ICI 182,780; Down 200; 1uM; PC3; HG-U133A" Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "BRAP,SYT13,MPDZ,CAMK2B,FAM189A2,AKAP7,ABI3BP,PPP6R2,SGSM2,COQ7,TBC1D16,FGFR1,HPCAL4,RUNDC3A,KCNMB4,GPR12,BTN2A1,AGFG1,KCNJ5,MAN2A2,MAP4,MPP2,ADAM22,POLG,PPP5C,MAPK10,KLK6,ATXN2,FAM102A,ELMO2,MAPKBP1,CDK19,ATP10B,EXOC7,NPDC1,ZNF24" Drug 6621_DN Lysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "CDC42BPA,CFLAR,MYRF,SCARB1,HOMER3,CPS1,CREM,NCOR2,ABCG1,SIPA1L1,RUSC2,ST3GAL6,ANKFY1,ERAP1,SRCAP,POLL,SHISAL1,IL6ST,MIA2,MMP16,NLE1,SH3TC2,ZNF821,ASAP3,FBXO11,ELMO2,KDM4B,CLASP2,SS18,SEPT8,ASTN2,SMG6,CABIN1,NR2C2,NAV3,EPM2A" Drug 1388_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "SYT13,PPFIA3,RIPK1,CFLAR,MTMR3,CAMK2B,LRBA,CREM,CRYM,RIMS2,ARHGAP32,ZNF337,DBT,DPH1,MPP6,OGA,ADAMTS13,CACFD1,MUM1,PADI2,MYO7A,OCRL,MINDY2,CNNM2,PTX3,CCDC40,RET,FAM102A,ELMO2,TSPYL2,STXBP1,ANKRD12,TNS1,UBE3A,TFIP11,SLC17A7" Drug 7352_DN Zalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG3,APC,CDC14B,MARK4,ATP6V0A1,ADAM15,CFLAR,C5,CA12,KYAT1,ARHGEF1,MAGI1,TAOK2,PLAA,RCHY1,CSNK1E,RIMS2,PRKAG2,SEMA4D,GPD2,RNFT2,HNMT,ITPKB,MITF,MMP16,SLC11A2,WDR25,BTBD7,ZKSCAN3,CLASP2,BEX4,XRCC4,REEP1,DNALI1,SMIM8,ACTR3B" Drug 7334_UP Apramycin [37321-09-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASPHD1,DOC2A,SEMA4G,PDE8B,ATP2A2,ATP6V0A1,MTMR3,CDH2,CACNA2D2,BAG4,CSF1R,SIPA1L1,ARHGEF4,DTNA,MAMLD1,EDNRB,SUGP2,EZH1,DISC1,GNG4,CNTRL,SPACA9,HNMT,MID1,MYCN,NF1,CDK18,RIPOR1,KHDRBS2,ZFHX4,ABLIM3,BTBD7,SMARCD3,KIF13A,RBM34,BEX4" Drug 3514_DN Lymecycline [992-21-2]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ABHD6,EPB41L5,PLA2G4C,MARK4,CFLAR,SYNJ2,SOCS6,HOMER3,AKAP7,SH2B1,ARHGEF4,DBN1,MFAP3L,RUSC2,RCAN1,OPTN,EGFR,STX2,EZH1,FHL1,MSL3,STON1,JAK2,MBD1,NEK1,NF1,CNOT4,TMEM104,RGS12,ANKRD6,VPS13A,KIAA0930,TRIM2,SLC44A1,CABIN1,RNF170" Drug 7434_DN Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "AP2A2,APC,FAM131A,APOC1,CDC14B,BCL7A,ST3GAL5,AP4M1,CREM,PDE4DIP,PPP6R2,GPRASP1,PARD6A,SEZ6L2,APH1A,IRAK4,CRCP,HNMT,MAP4,MIA2,NPR2,SLC25A23,RETREG2,POLG,CEP97,CCDC25,FBXW7,FBXO11,NUBPL,SMARCA4,SPATA7,PHLDB1,TRIM2,TIAM1,PARD3,KAT6B" Drug 7288_DN Thalidomide [50-35-1]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NME5,BIN1,FAM131A,ST3GAL5,TAOK2,CLCN3,QKI,GIT2,ACOT8,F8,ACSL4,SCARA3,CINP,COPS8,CNTRL,RASSF8,NF1,NFIX,SLC11A2,ELOVL2,MCMBP,RPS6KA2,CLIP1,FAM102A,BTBD7,SMARCD3,ZBTB43,WSCD1,BHLHB9,R3HDM1,HIRA,LMF1,XRCC4,ZNF45,EVI5,PHTF2" Drug 1496_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "NDRG3,FAM131A,CDK10,MARK4,BMP7,SYNJ2,MTMR3,QKI,GIT2,RCAN1,OPTN,ANKMY1,ZNF589,SEMA4D,PRELID3A,USP19,TXNL4A,FERMT2,ITPKB,MEIS1,MIA2,SCAMP5,NEK1,SLC25A23,SUSD4,ABLIM3,BTBD7,ZNF423,ZBTB43,MCF2L,KIAA0930,TRIM2,PARD3,SEMA3B,EPM2A,SMIM8" Drug 1609_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.68E-03 1.00E+00 1.78E-02 2.01E-01 36 197 "ASIC1,PKP4,APBB2,CDK10,SYNJ2,RUNX1T1,SEC31B,SPOCK2,SGSM2,EGR3,ANKMY1,FKTN,ZNF589,OLFM1,BAIAP2,OGA,AHDC1,GSTM5,MAP4,NELL2,NTRK3,P2RX7,PLCD1,RETREG2,CNNM2,CCDC40,SLC11A1,KBTBD4,ELMO2,DOP1A,ZHX3,UHRF1BP1L,ZC3H13,ELP5,REEP1,URM1" Drug CID002733635 Fm 4-64 Stitch 2.68E-03 1.00E+00 1.78E-02 2.01E-01 20 91 "SYN3,DYNLL1,CACNA1B,CALM1,RHBDL1,LRBA,CLTC,SNAP91,GPHN,STX2,NBEA,GPR162,TXNL4A,MYO5A,PTPRN2,SYBU,STX1A,SYN2,SYP,ACTR6" Drug CID000000896 melatonin Stitch 2.69E-03 1.00E+00 1.79E-02 2.02E-01 70 443 "ADCY5,ADCY6,ADCY8,ADRB2,AMT,KCNAB2,APLP1,ARNTL,ARRB1,ARRB2,NCOA1,CACNA1A,CACNA1B,CALM1,KRIT1,RGN,LRBA,COL4A5,CLOCK,CREM,CRHBP,CRY2,CSNK1E,BOC,GSDME,HS3ST2,DYNC1I1,NR1D2,KAT8,AGAP2,MALT1,TCERG1,COPS8,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KAT7,TNFAIP8L3,IGF1,KCNH2,KITLG,NPY,NOVA2,OPRL1,OXTR,ABCB1,PRKACB,PRKCB,PRODH,RORB,CLIP1,SAFB,FOXRED1,SLC11A1,SST,ALG1,MGRN1,ZEB1,ARHGAP9,KAT6B,TST,CLIP2,KCNAB1,KAT6A,FXR1,JPH3" Drug CID003036508 Pc 12 Stitch 2.71E-03 1.00E+00 1.80E-02 2.03E-01 38 211 "ADCY6,ADORA1,ADORA2A,APLP1,LRBA,CHGB,CHRNA4,NRG2,GPSM1,RCAN1,RGS17,ERBB4,PTK2B,PPP1R1B,FGF1,SMC2,ATP2C1,GNAO1,GRIA2,CPT1C,NPY,NTRK3,PCSK1,PRKACB,PRKCB,MAPK3,MAPK9,MAPK10,PRPH,QDPR,RAP1GDS1,SNAP25,SYN2,SYP,SYT1,TK2,TMPO,SLC30A3" Drug CID000002071 "1-aminoindan-1,5-dicarboxylic acid" Stitch 2.76E-03 1.00E+00 1.83E-02 2.07E-01 10 33 "APAF1,KCNMB4,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,MAP4" Drug CID000104916 CGS 8216 Stitch 2.76E-03 1.00E+00 1.83E-02 2.07E-01 10 33 "DBI,ZMYND10,GABRA3,GABRB3,GABRG1,GABRG2,MCHR1,SST,SSTR1,SSTR2" Drug CID000006334 propan Stitch 2.76E-03 1.00E+00 1.83E-02 2.07E-01 10 33 "KDM5D,ATP6V0A1,CDO1,DTNA,SDCBP2,MEST,NPTX1,PDZD2,ST5,FTSJ1" Drug 7053_UP thapsigargin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.78E-03 1.00E+00 1.85E-02 2.08E-01 32 170 "AK2,ST3GAL5,SYNGR3,ARHGEF2,CLGN,FAM189A2,RCAN1,MBNL2,AMOTL2,SEC23B,UFM1,FYN,SRCAP,GRB10,FICD,MIA2,SLC11A2,NUCB2,DCUN1D2,SH3BGR,PPM1E,SHMT2,SEC31A,PEX26,ZSWIM8,TSPYL2,CAMTA2,MCF2L,TRIM2,VAV1,VLDLR,FTSJ1" Drug CID005486547 YM90K Stitch 2.78E-03 1.00E+00 1.85E-02 2.08E-01 8 23 "GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CABIN1" Drug CID000127607 griseolic acid Stitch 2.78E-03 1.00E+00 1.85E-02 2.08E-01 8 23 "PDE8B,ALDH7A1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000005917 pentylenetetrazol Stitch 2.83E-03 1.00E+00 1.88E-02 2.12E-01 26 130 "ADORA1,ADORA2A,CA4,CACNA2D1,DBI,SV2B,EXOG,STX2,ADGRV1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,GRIA2,GRIN2C,GRIN2D,KCNN2,MEST,NPY,PTCH1,SST,SYN1,SYN2,MLST8,ZEB1" Drug CID000105153 rubidium Stitch 2.84E-03 1.00E+00 1.88E-02 2.12E-01 15 61 "AGT,ATP1A3,DDR1,SLC12A6,KCNB1,KCND2,KCNH2,KCNJ5,AFDN,NBL1,SLC11A2,P2RX7,SLC12A2,SLC12A4,SLC14A1" Drug CID000068258 5-hydroxytetralin Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 9 28 "TAOK2,MEST,CNTN3,PAX6,PDCD2,PRPSAP2,SAFB,TEK,RASD2" Drug CID005364123 CI-937 Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 6 14 "CACNA2D1,CLTB,MX1,ABCB1,MAPK9,MAPK10" Drug CID000073026 HOOBt Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 6 14 "BOC,CHRDL1,GGT7,GGT5,PTN,TK2" Drug CID000052396 P-81 Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 6 14 "AGT,CALM1,CAMK2B,KRIT1,MBP,MAPK3" Drug CID000033360 ethofumesate Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 6 14 "AGT,CIT,RNASEL,STX1A,NPL,EPM2A" Drug CID000093197 end germ Stitch 2.85E-03 1.00E+00 1.89E-02 2.13E-01 6 14 "BLM,CLGN,EBF1,FGF1,FGFR1,WRN" Drug 5210_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "ADRA1D,OSBPL1A,BIN1,APBA2,GAS7,ST3GAL5,CTH,INTS1,RUSC2,CDON,RCAN1,MBNL2,BAIAP2,AFF2,ATP2C1,ERAP1,SRCAP,GLYR1,GRB10,DIDO1,NF1,OXTR,PLCD1,DCHS2,KLK6,HSPA4L,SGK1,SH3BGR,CPEB3,CCDC88A,TRIM2,UCHL1,VLDLR,FXR1" Drug 573_UP deferoxamine mesylate salt; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "AMPD3,APAF1,APBA2,ST3GAL5,CBFA2T2,SCARB1,CHRNA4,PICK1,CNTN1,ARHGEF10,FEM1B,EGFR,ENO2,OLFM1,IP6K2,SOX21,ADAM22,MXI1,OGG1,PDE1C,PFKFB3,PFKFB4,MAPK3,PTPRN,RGS12,RNASE1,RNASEL,TCP11L1,SH3BP2,KDM4B,KDM3A,OBSL1,VLDLR,SLC17A7" Drug 4430_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "AP2A2,ARRB2,LHX2,RAB26,NRG2,FAM131B,DCAF8,DTNA,HIPK3,FYB1,AHDC1,KCNMB4,GUCY1A1,SHISAL1,MEF2C,ZNF862,NF1,STRN3,FA2H,MAPK7,FAM184A,BEND5,PPP4R3A,SNCA,DDN,COBL,IQCE,GPR161,ZKSCAN5,TRIM9,MAP3K12,PCBP4,EPM2A,PHTF2" Drug CID000104727 aluminum Stitch 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "ADCY5,ADCY6,ADCY8,APBB2,ATP1A1,BCHE,DST,CALM1,CNOT8,TBPL1,PLCXD3,ARHGAP32,ELN,GNAL,GPT2,STON1,HBA1,IDH3A,IDH3B,MAP2,MAPT,NEFM,NEFH,PKM,PLCB2,PLCD1,PPP3CA,PPP3CC,RELN,QDPR,SNCA,PLCB1,TBL1X,CABIN1" Drug 5027_UP Etoposide [33419-42-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "LTBP4,APC,RGS20,N4BP2L1,CFLAR,ST3GAL5,SCAPER,CFAP410,TPP1,CRY2,HIPK3,ELN,HSD17B14,VPS13B,KAT8,SRCAP,SESN1,GLYR1,POLL,GPER1,GRIK5,ATXN2L,ICA1,MAP2,FAM214B,ASTN2,EXOC7,KIAA1107,ZMAT3,BEX4,CDK20,ZFP37,MAP3K12,SEMA3B" Drug 1321_DN Apigenin [520-36-5]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "ADRB2,APAF1,FUBP1,RCBTB2,QKI,HDAC9,KIAA0586,EXOG,FRY,SYNCRIP,PDLIM5,STAU2,MALT1,GLUL,DIDO1,IRAK3,IRF8,IFI16,SMAD1,MEIS2,NCF2,NEK1,PRPSAP2,PTCH1,SLA,SLC6A8,ARHGEF40,GLT8D1,KDM4C,CLASP2,JMJD6,KIAA0930,TPM1,SSBP2" Drug 1344_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.87E-03 1.00E+00 1.89E-02 2.13E-01 34 184 "ABR,STX16,KRIT1,CNOT8,CLCN3,QKI,SOCS5,DCAF8,TBC1D5,EPB41L2,GPHN,IGSF6,ERAP1,ARFIP1,GLUL,HSF2,MBNL1,CNOT4,PLEC,LRP12,MINDY2,SAMD9,PTK2,RDX,MCMBP,SLC2A5,ELMO2,SMARCA4,NXT2,DICER1,TMPO,CLDND1,NLRP3,RNF146" Drug CID000065829 TG-51 Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "ZBED1,PREPL,OPA1,SNCA,NPL" Drug CID000056205 difloxacin Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "NUMBL,ZMYND10,PDCD2,SLC14A1,TRIO" Drug CID000071698 mepindolol Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "ADRB2,TBPL1,AASS,ZMYND10,PAX6" Drug CID000028936 bromopropylate Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "ARSE,APPL1,GPT2,CLSTN2,TP53BP2" Drug CID000194104 Bursin Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "NELFCD,RPS6KA2,SST,TMPO,UBC" Drug CID000141200 isobutyllithium Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "SOCS5,BOC,POLL,SYNE1,GAN" Drug CID000002427 BPIQ-I Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "EGFR,ERBB4,PTK2B,MAPK3,PTK2" Drug CID000194032 gamma-methyl-L-leucine Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "EDNRA,EDNRB,OPA1,EXOSC10,ARHGAP9" Drug CID006439129 AC1O5R1H Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "ACHE,BCHE,NPTX1,NPTX2,FXYD1" Drug CID000028118 HBF4 Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "MATK,SLA,SP2,CLSTN2,SYNE1" Drug CID009543502 FF 3 Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "CSF1,CSF1R,FLT1,KITLG,VAV1" Drug CID000407006 6-chloro-5H-purine Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "ADORA1,EXOSC10,RNASE1,SALL1,SYNE1" Drug CID004369409 AC1NA019 Stitch 2.90E-03 1.00E+00 1.89E-02 2.13E-01 5 10 "LHX2,CTH,IGSF6,MAT2A,RDX" Drug 6884_UP AG-012559 [369370-06-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "AK2,STX16,CFLAR,ZMYM4,ENTPD4,SLITRK5,RIMS2,TBC1D5,DBT,DMPK,FCF1,APH1A,TUBD1,FGFR1,MSL3,GRIK5,ICA1,SCIN,IL6ST,IL12A,MAPT,ADAM22,MINDY2,SNRK,MCMBP,SAFB,NUBPL,ZNF430,RBM34,ZBTB43,POGZ,SS18,ASTN2,TRIO,HIRA" Drug 7438_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "AP2A2,EPB41L5,APOC1,CDK10,RIPK1,BMP7,CCNT1,ARHGEF1,TAOK2,CSNK1E,DNM1,DPH1,DTNA,EGR3,FGFR3,GHR,FERMT2,MMP16,NFYA,PCDH9,PRKAR1B,SAFB,SEC14L1,SH3BP2,BTBD7,SMARCA4,CDK5RAP2,TMCC1,PHLDB1,TACC1,TIAM1,BEX4,SSBP2,PLPPR2,ST7" Drug 7070_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "MPDZ,BID,SLC25A14,AP4M1,ARMC8,WHRN,PDE4DIP,TBC1D5,DBN1,ZNF804A,FCF1,KMT5B,EIF5,TUBD1,ETV1,CHST15,PDLIM5,TXNL4A,ACOT7,JAK2,CNOT4,NPR2,PLEC,MBOAT7,MAPK7,RGS3,COA1,PDZD2,ARHGEF9,SYT1,TRIM2,TST,NDRG4,PCBP4,ACTR3B" Drug 2911_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "BIN1,APBB2,EPB41L5,BCAS1,ATP6V0A1,KALRN,CBFA2T2,CDO1,SULT4A1,COL9A3,CSF1,SIPA1L1,FAM169A,AFF2,GRIK5,TJAP1,SCAMP5,GIT1,MSI1,ADAM22,ZNF862,NRCAM,PDE4B,PFKFB4,NLE1,NECAB2,SH3BP2,ARHGAP26,RBM26,ATP10B,SYT5,TAL1,CRTC1,KLC2,PCBP4" Drug 1243_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "RALGAPA1,N4BP2L1,C5,IL33,WHRN,AKAP12,HAPLN1,ABCG1,VCAN,EDIL3,ING4,INPP5K,MSL3,STON1,GPER1,BACH2,KCNF1,KIFC3,MT1M,ZNF862,MAPK7,DZIP1,SLC4A3,ZKSCAN3,SMARCD3,IFT122,KDM4C,DNAH7,GPR161,HEY1,CABIN1,WIPF1,LAMP5,EMSY,PLSCR4" Drug 6776_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "AK2,TRMT9B,AMT,CDK13,RGS9,CFLAR,RAB29,SIPA1L1,JAKMIP2,PTK2B,PDLIM5,FYB1,LILRA2,STMN2,ADAMTS13,CACFD1,TJAP1,IL6R,JAK2,MAP4,MX1,ZNF862,NPTX1,PLEC,PRKCB,PTPRB,ASAP3,PLCB1,ZNF34,TIAM1,TNS1,UCHL1,KCNK12,ZNF24,KAT6A" Drug 1418_DN Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; HL60; HG-U133A Broad Institute CMAP Down 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "ACADM,CLK4,AMPD3,CFLAR,CCNT1,HDAC9,MATR3,DBT,DMTF1,KCTD3,EPB41L2,SUCO,SEC23B,TRMO,MALT1,AGFG1,JAK2,MBNL1,PFKFB3,TRHDE,PPM1B,CNNM2,C1orf54,REV3L,PCMTD2,CLIP1,PEX26,CCDC88A,NXT2,ANKRD12,METTL3,ELP5,ZNF24,ZNF189,ST7" Drug 6479_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.90E-03 1.00E+00 1.89E-02 2.13E-01 35 191 "ADCY6,AP2A2,APC,PPFIA3,SLC4A4,DGKI,CLGN,WHRN,CSF1,RIMS2,EGR3,EIF4G2,ACSL4,ZNF589,FHL1,GAD1,ICA1,JAK2,PACRG,MBD1,MBNL1,MYT1,PALM,PURG,C1orf54,ZNF493,RET,KLHL11,SYBU,IZUMO4,ARHGEF9,SMG6,WIPF1,SLC30A4,EMSY" Drug ctd:C419410 "N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester" CTD 2.91E-03 1.00E+00 1.89E-02 2.13E-01 12 44 "NUMB,CDH2,CSF1,ENO2,TUBB3,FOXO3,FLT1,RBPJ,ITGAM,MAP2,HEY1,TLR4" Drug 2832_DN Phenacetin [62-44-2]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,ABHD6,SRPX,APOC1,EIF4G3,CAMK2G,QKI,SMARCAL1,USP6NL,DAPK3,TOM1,EDNRA,FAM198B,CGREF1,B4GALNT1,DISC1,POLL,SLC2A6,MUM1,NEK1,NPR2,PDCD2,SLC25A23,PRPH,ZC3H14,TCP11L1,SUPT20H,SIRT2,ZKSCAN3,KDM4B,VPS13A,VAV1,VGF,WIPF1,ZBTB14,SEMA3B" Drug 1904_DN Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADRB2,MARK4,BCL7A,BID,HIP1R,ARMC8,SOCS5,KIAA0753,MAMLD1,SEZ6L2,PCOLCE2,DCTN4,EPB41L2,BAIAP2,AMOTL2,DBF4,PRRC2B,HAS2,LAMP2,MKLN1,NEK1,MAPK3,C1orf109,CEP97,MSANTD2,ABLIM3,SLC2A5,SLC12A2,ZEB1,HEY1,CBX5,R3HDM1,TRIO,PLPPR2,SPHK2,NAV3" Drug 2068_DN Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APBA2,KCNAB2,CFLAR,TAOK2,EPS15L1,ARHGEF6,CDC42BPB,DZIP3,ARHGAP32,ZFYVE16,KIAA0586,FBXL5,SGSM2,SPEG,EFCAB2,POMT1,MATN3,ZNF862,SETD4,NLE1,MAPK7,ASAP3,ST6GAL1,FAM214B,SMARCC2,CDK5RAP2,SPTAN1,ST5,ELOVL4,ARHGEF9,IQCE,TBL1X,TRIM2,FAM155A,WNT7A,NDRG4" Drug 7096_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BIN1,CFLAR,ENTPD6,HOMER3,DCAF4,ZFYVE16,ZNF589,FGFR1,BAIAP2,FHL1,TPK1,OGA,CRCP,FERMT2,GUCY1A1,GUCY1B1,SLC2A6,MKLN1,NPR2,PAX6,PDE1C,PLCD1,POLG,PPP5C,TMEM104,MCMBP,SBF1,ATXN2,CCDC88A,TSPYL2,SIK3,MTMR14,TK2,SMIM8,ACTR3B,AAAS" Drug 2657_DN Arecoline hydrobromide [300-08-3]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ACTN1,BIN1,CDC42BPA,APC,BCAS1,PPFIA3,SYNJ2,KYAT1,VAX2,QKI,DCAF8,ING4,CDKL3,VPS26C,FGFR1,BAIAP2,AGAP2,POLL,GRIK5,IL6ST,IPO5,LIG4,MAP4,NPR2,SLC25A23,RAD51D,RNASEL,EMID1,BTBD7,SNCA,ASTN2,KIAA0930,TRIM2,XRCC4,HPS4,MPPE1" Drug 3465_UP Amrinone [60719-84-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NME5,AK2,SRPX,AMPD3,AMT,KCNAB2,CFLAR,HOMER3,SH2B1,CSF1,DAPK3,PARD6A,FAM49B,ERAP1,SEPT9,GFER,USP19,STON1,SPACA9,MAP4,ZNF862,NTRK2,ZSCAN2,GTDC1,RGS12,RNASEL,FBXW7,FAM214B,TMCC1,KDM4C,UNC5B,CDK19,PHLDB1,PLCB1,THRA,NT5M" Drug 7252_DN Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BIN1,PPFIA3,KYAT1,IQCK,SMARCAL1,NCOR1,USP6NL,DCAF8,B3GAT3,PARD6A,TNK2,FCGRT,FHL1,ARFIP1,SESN1,TXNL4A,SLC2A6,KHK,MEIS1,MYO6,OCRL,CCSER2,NLE1,MBOAT7,POLG,FSD1,SEC14L1,PEX26,ELMO2,CDK5RAP2,IFT122,ZNF415,SPATA7,LMF1,MPPE1,TIGD6" Drug 4761_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,ASIC1,RASL11B,LDLRAD4,CFAP410,RHBDL1,USP2,CDH2,CDO1,SULT4A1,ARHGEF6,RCHY1,AATK,DAPK1,SPOCK2,EPB41,MTSS1L,NRN1,PTK2B,FGFR1,FYN,GSN,KCNH2,KHK,AFDN,ADAM22,GPR85,PFKFB2,DCUN1D2,LIMS2,SLC8A1,ZNF415,HECW1,TROVE2,DOCK9,ST7" Drug 2918_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AMPD3,CDC42BPA,APBB2,APOC1,ARHGDIG,RHBDL1,CCK,CBFA2T2,CNTN1,IQCK,SLC4A8,SH2B1,ABCG1,CDON,EIF4G2,RASGRP2,TLR7,CSDC2,CACFD1,IL12A,SCAMP5,ADAM22,MYO6,ZNF862,FXYD7,PDE4A,KCNIP1,CXXC4,SPTAN1,DIP2A,PLCB1,EXOC7,PCDHGA10,PCDHA3,TK2,VIPR2" Drug 1377_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG3,APAF1,MTMR2,WASF1,CAST,ARHGAP33,DAPK3,ANKRD46,VPS26C,TRMO,STAU2,OGA,GLYR1,INPP5B,ITGAM,KCNN2,IPO5,MBD1,NFE2L2,ENPP2,PLEC,SLC25A23,ZNF426,RBBP8,CLIP1,ATXN2,HSPA4L,SGK1,FUZ,SEC31A,MAPKBP1,ZSWIM8,DBNDD2,TSPYL2,ITPRID2,EVI5" Drug 5545_DN Isoflupredone acetate [338-98-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "PPP4R4,MARK4,ADAM23,ADAM15,CFLAR,MTMR2,BAIAP3,ARHGAP33,LRRFIP1,TAOK2,FAM189A2,QKI,GIT2,DUSP9,ANKMY1,PRELID3A,CNTRL,SPACA9,HNMT,KCNQ3,LMO2,MAP4,RETREG1,RGS12,GSTCD,NEK11,PPP4R3A,SNCA,ZHX3,EXOC7,TNS2,PIK3R5,HIRA,VAV1,EMSY,KAT6A" Drug 7126_UP Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "MTUS1,NME5,BIN1,KIF1A,RGS11,SCAPER,SOCS6,PLAA,AKAP7,PPP6R2,FAM131B,DAPK3,C2CD2L,DTNA,FAM13A,COQ7,SPEG,RRAGB,SCARA3,OGA,FYN,ERAP1,FICD,INPP5B,JAK2,MX1,NF1,PFKFB2,SAMD9,MCMBP,SUPT20H,CHD9,PEX26,SZT2,SLC35G2,METTL3" Drug 7193_DN Streptozotocin [18883-66-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BRAP,BIN1,CDC42BPA,CDK10,NCOA1,ATP6V0A1,SCAPER,ARHGEF1,FOXN3,CSNK1E,DTNA,TSPAN5,EIF4G2,CGREF1,FYN,SEPT9,HNMT,KCNF1,MATK,MBD1,MEIS1,OGG1,PRKAR1B,TMEM104,NKAIN1,CCDC25,BTBD7,SPATA7,UNC5B,ZBTB43,ELOVL4,ASTN2,MCF2L,RPRM,VGF,TIGD6" Drug 4830_UP Piperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SYN3,NME5,APC,CDC14B,CDK13,RGS9,LDLRAD4,ARHGEF1,SULT4A1,ARHGEF6,AKAP7,GREB1,SNPH,PLXNC1,EIF4G2,RASGRP2,NRN1,DISC1,PCLO,ATXN2L,LAMA2,MSR1,PDE1C,ENPP2,PLTP,MRAS,CCDC88A,HECW1,ZC3H13,JMJD6,WSCD1,DMXL2,PCDHGA10,KCNAB1,FAM13C,DPF3" Drug 2947_UP Risperidone [106266-06-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AGT,CDC42BPA,APOC1,KIF1A,CALB2,ARHGEF10,SPOCK3,CELSR3,ELN,VPS13B,RASGRP2,CAMKK2,PRELID3A,SEPT9,GATM,TJAP1,SMAD1,AFDN,CNOT4,NLE1,TCP11L1,GALNT10,RASA3,FUZ,CCDC92,EPN2,BTBD7,ARHGAP26,PDLIM2,CUX2,TRIM2,SZT2,SLC44A1,CDK20,UBTF,EVI5" Drug 6302_DN Chlorhexidine [55-56-1]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APOC1,ADAM15,CFLAR,C5,KYAT1,QKI,CREM,VCAN,GPRASP1,PLPPR4,SLC12A6,DCTN4,ANKMY1,PDLIM5,MSL3,GPR37,MAP4K5,SHISAL1,FAM69A,ZNF862,SLC11A2,PCDH9,MINDY2,PRPH,FUZ,ANKRD6,KBTBD4,TMCC1,ZBTB43,EXOC7,TNS2,WIPF1,KLC2,XRCC4,URM1,SMIM8" Drug 2905_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BIN1,CDC14B,ATP6V0A1,CLGN,STOML1,CNTN1,SPOCK2,DTNA,FAM13A,MRNIP,RRAGB,SH3YL1,SEC24B,GAA,RAB40B,KIFC3,MAP4,TM6SF1,AFF1,ADAM22,NTRK3,NLE1,SMOX,SLC25A23,LRP12,PPARA,LRRN3,CEP41,BCAS3,TCP11L1,SH3BP2,ARHGAP26,TBCEL,SZT2,ZFP37,PRDM10" Drug 605_DN monastrol; Down 200; 20uM; MCF7; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "C1QTNF1,AMPD3,CDK10,PDE8B,ADGRB1,SYNJ2,SYNGR3,CLTB,ARHGEF10,USP6NL,CALCRL,COQ7,BAIAP2,FOLR2,RASL10A,ERAP1,LUZP2,TREM2,PLCD1,CEP41,ELOVL2,ZSCAN32,RGS4,TCP11L1,ZNF821,SH3BP2,KBTBD4,DOP1A,PEG10,ATP10B,SEPT8,EXOC7,TBL1X,WNT7A,ZNF189,MPPE1" Drug 6242_DN Skimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,BRAP,MTUS1,MAP4K3,MARCH3,BMP7,SYNJ2,KRIT1,SYNGR3,LHX2,CSNK1E,SOCS5,DZIP3,PPP6R2,GIT2,PCOLCE2,FAM49B,CSPG5,CRCP,KCNMB4,GNG4,MMP16,PLXNB1,CCDC25,SAFB,AMBRA1,KDM4B,SPTAN1,ANKRD12,CABIN1,SSBP2,HIRA,ZNF23,REEP1,UPF3A,MAP3K12" Drug 2020_UP Azacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADORA1,CDK10,PRX,PDE8B,ADGRB2,CA12,CACNA1A,CALB2,SPAG9,CHN2,CNTFR,KIAA0586,TMCC2,TNK2,SRPK3,ELN,PIPOX,TRMO,ALDH1L1,SPACA9,CACFD1,KCNF1,MBP,GIT1,NFYA,DUSP26,RETREG2,PPP5C,RGS12,RXRA,SLC2A5,LIMS2,SYN2,DNAH7,VGF,VIPR2" Drug 3426_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,EPB41L5,EIF4G3,SYNJ2,MAGI1,CSNK1E,PDE4DIP,GPRASP1,GIT2,DBN1,DNM1,DTNA,TNK2,DENND4A,SRCAP,ZNF276,CNTRL,SLC2A6,MAP4,SETD4,SLC25A23,ELOVL2,RAD51D,GTDC1,RNASEL,CCDC25,EPN2,ZBTB43,THSD1,ELOVL4,TACC1,TPM1,HIRA,ZNF189,EVI5,PHTF2" Drug 6196_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,BIN1,SEMA7A,APAF1,NRP2,CA4,STOML1,SULT4A1,PDE4DIP,KLHL3,HSD17B14,ERBB2,F5,IQCG,NEU3,STON1,PCLO,TPPP,MAP2,MGAT3,MPP2,TREM2,PCDHGC3,PRPH,ACSS3,RGS12,EPN2,KDM4B,PEG10,SS18,TRIM2,PCDHA5,GPR161,TRIO,VSNL1,FAM13C" Drug 5352_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,AP2A2,FAM131A,APOC1,ATP6V0A1,CA4,CAMK2G,SLC16A4,CPS1,SH2B1,CRY2,PPP6R2,DAPK3,SGSM2,DTNA,SMC2,SRCAP,FERMT2,TDRKH,GPER1,LSS,MGAT3,LYRM9,SLC11A2,PIK3R1,RETREG1,RGS3,GSTCD,SH3BP2,FNDC3A,AP4E1,TRPM2,EVI5,KCNAB1,MPPE1,UBE3B" Drug 2803_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NME5,APBA2,KSR1,SCAPER,GYG2,SLC16A4,RCBTB2,DBT,HSD17B14,STX2,FGF12,OGA,SRCAP,TDRKH,HLF,ICA1,MAP4,GIT1,P2RY1,PCDH9,LRP12,C1orf54,RGS3,RGS12,STUM,LIMS2,KIF13A,SPTAN1,SPART,ST5,KIAA1107,CRTC1,DICER1,CABIN1,ITM2C,TIGD6" Drug 2062_DN Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,AK2,AMT,OGT,MPDZ,CFLAR,CSNK1E,USP6NL,SNPH,C2CD2L,SGSM2,SCML2,SRCAP,TXNL4A,PCLO,MAN2A2,MAP4,MITF,ZNF862,NFYA,SETD4,NLE1,PLCD1,POLG,SBF1,SH3BP2,ZKSCAN3,TTBK2,ARHGEF9,CLASP1,UBTF,LMF1,KLC2,ZBTB14,SMIM8,PHTF2" Drug 6812_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,ADRA1D,ATP6V0A1,GYG2,CRLF1,AKAP7,CSF1,CSF1R,RIMS2,PARD6A,MED12,TNK2,FHL1,SEMA4D,SRCAP,GNG4,JAK2,MAP4,KITLG,GIT1,RETREG1,PPP5C,MAPK7,WDR25,ZSCAN32,NEK11,SLC9A5,ARHGAP26,CDK19,TROVE2,CEP68,ARHGEF9,IQCE,SLC44A1,ZKSCAN5,EPM2A" Drug 762_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,ADD2,AK2,AMT,APBA2,APBB2,ARNTL,CFLAR,CA12,NFS1,KRIT1,SOCS6,TAOK2,CDC42BPB,ZNF337,B3GAT3,ANKRD46,MBNL2,FCGRT,DENND2A,PRRC2B,CNTRL,RNFT2,SMAD1,MKLN1,MAPK3,TMEM104,CCDC25,ZC3H14,MAPK12,SIRT2,KBTBD4,ELMO2,ZHX3,ST5,ZNF184" Drug 3185_UP Mifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,ALK,LGR5,PPP4R4,OSBPL3,VCAN,RIPOR2,HEPH,RUSC2,TLR7,FGFR1,AGAP2,SIGLEC8,TOX3,GPR37,GRIK5,CACFD1,ICA1,LSS,MEF2C,ADAM22,PCDH8,MAPK10,FAM184A,RASGRF1,RFX2,RORB,FRMPD1,ZNF415,ARHGAP26,R3HDM1,PIK3R5,TUBB1,WNT7A,ZNF711,ZNF45" Drug 1579_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APAF1,BMP7,CAMK2B,CAST,MAP4K4,AKAP7,CSF1,DAPK1,C2CD2L,ANKRD46,ZNF589,FLNC,ATP2C1,PRRC2B,KCNN1,KHK,MYT1,NEFH,NTRK2,PDE1C,PLCB2,PPP2R2B,MAPK3,PTK2,CCDC40,ZNF671,SAFB,SCN2B,SH3BP2,SLA,ELMO2,SMARCA4,ZC3H13,IQSEC2,OBSL1,MFF" Drug 4697_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "KDM5D,NDRG2,ADD2,NME5,LTBP4,SEMA4G,SLC4A4,QKI,RCHY1,CREM,ARMCX2,ELMO1,DPH1,ING4,ANKFY1,GALC,RUNDC3A,GLYR1,GRB10,GSN,ELOVL5,TJAP1,LIG4,AFDN,MMP17,PLCD1,LRP12,C1orf54,ROBO1,ZNF821,SLA,FAM214B,KDM4C,KAT6B,OSBP2,VGF" Drug 702_DN alpha-estradiol; Down 200; 0.01uM; PC3; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SYT13,APBA2,CDK10,SLC4A4,NRP2,CDC42BPB,NCOR1,INTS1,B3GAT3,HSD17B14,TMEM164,HPCAL4,SEPT9,INPP5K,TXNL4A,GPR12,RASSF8,AGFG1,KCNJ5,KIFC3,MAP4,GIT1,ADAM22,NELL2,PLCD1,MBOAT7,POLG,PPP5C,RAP1GDS1,NUDT11,RPS6KA2,MAPKBP1,MLST8,CBX5,AAAS,DPF3" Drug 2767_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,C1QTNF3,APC,PPFIA3,BMP7,GYG2,PLEKHB1,FAM189A2,RAB26,HOMER3,CSNK1E,PDE4DIP,ARHGEF4,CELSR3,TNK2,ANKMY1,SEMA4D,SRCAP,AHDC1,AGBL5,MAP4,ZNF862,NPR2,PLEC,MCMBP,SBF1,SEC14L1,TSPYL2,STX1A,OBSL1,TMEM121,ZNF34,CABIN1,PLPPR2,VGF,HPS4" Drug 3749_UP Solasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SEMA6A,SLC4A4,CACNA1A,KALRN,SULT4A1,ERC2,BRINP1,EPHB1,ETV1,FGF12,NSG1,ADAMTS13,GRM2,AP4S1,IRAK3,IRF8,KCNB1,KCNN2,TAGLN3,LYRM9,NRCAM,PTPRB,SEMA6D,ST8SIA1,PREX2,PPP4R3A,KANSL3,MCF2L,TAL1,KLHL4,PCDHGA10,PCDHA6,SLC44A1,TPM2,PDIA2,FLRT2" Drug 3419_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,SPARCL1,LTBP4,APBA2,APBB2,LDLRAD4,USP2,PLAA,CRY2,HINFP,CSF1R,FAM169A,DZIP3,DCAF4,DCAF8,DBT,DPH1,C3orf18,FGFR1,FHL1,INPP1,ITPKB,LSS,KITLG,PTPRO,ELMO2,SPART,ASTN2,IQCE,WSCD1,ZNF34,TK2,ZBTB38,GDPD5,EPM2A,SMIM8" Drug 2200_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,MTUS1,ANK2,APOC1,MYRF,CBFA2T2,LARGE1,SOCS6,VCAN,GPRASP1,HIPK3,PLXNC1,EIF1,RASGRP2,RRAGB,F5,PTK2B,CSPG5,GALC,IL6ST,MAP4,MEF2C,AFF1,GIT1,CNOT4,OXTR,PDE4D,RIPOR1,TCP11L1,MAP6D1,LIMS2,ZNF667,SPTAN1,DDN,JMJD6,ZNF34" Drug 4323_UP Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,ASIC1,BEGAIN,SEMA7A,APC,BMPR1B,FUBP1,BAIAP3,THSD7A,STOML1,EZH1,KAT8,HPCAL4,TRAF3IP2,NELL2,NPR2,NPTX2,NTRK2,PCSK1,RETREG1,FSD1,GRAMD1C,ZMAT4,RGS4,ZNF821,DZIP1,DHX30,FAM214B,IQSEC2,THSD1,PLCB1,SYN2,CABIN1,CDK20,CHST5,ZKSCAN5" Drug 5429_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SYN3,SEMA4G,PPP4R4,LDLRAD4,CHRNA4,CSF1R,SV2B,HS3ST2,SLC12A6,EDNRA,EGFR,ING4,ELN,C3orf18,ERCC2,ALDH1L1,RUNDC3A,HPGDS,TJAP1,ITGA7,MAP4,MSR1,LRRN3,PRKCB,MAPK7,SH3BP2,FAM214B,ARHGEF40,PDZD2,ZHX3,SPTAN1,CDK19,TNS1,TPM1,PLPPR2,PLSCR4" Drug 6314_DN Vigabatrin [60643-86-9]; Down 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ALDH7A1,CA12,CCNT1,CREM,SIPA1L1,CNTNAP2,B3GAT3,C2CD2L,LYPD1,SPOCK3,FEM1B,ING4,SPEG,FGFR1,PRRC2B,TDRKH,BTN2A1,MAP4,MEIS1,TAGLN3,PLEC,CNNM2,RAD51D,SH3TC2,FAM102A,NLGN1,KDM4D,CDK5RAP2,IFT122,ELOVL4,ARHGEF9,WSCD1,TCF4,TK2,SSBP2,XRCC4" Drug 2708_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,TRMT9B,AMPH,APBA2,KIF1A,CAPN3,LARGE1,TAOK2,STOML1,PICK1,SLC4A8,HAPLN1,NCOR2,AATK,RIMS2,EXOG,DLC1,SIGLEC8,SEPT9,POLL,SPACA9,SCAMP5,MMP17,OXTR,FSD1,LRRN3,RGS4,SNCA,SPTAN1,TACR1,TAL1,CHST8,TNS1,RUNDC3B,WNT7A,SLC17A7" Drug 2668_DN "estradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,TRMT9B,AMT,CACNA1G,IQCK,SGSM2,CDON,ING4,MRNIP,ELN,PIPOX,ZNF44,SEPT9,GATM,RUNDC3A,GRM8,MAP4K5,ATXN2L,TJAP1,MAPT,MID1,MYO6,WDR25,KHDRBS2,SCN2B,GALNT10,CCDC92,ANKRD6,EPN2,ARHGAP26,OBSL1,TNS2,CDK20,TRIO,CLIP2,XRCC4" Drug 871_DN ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,ADCY6,CDK10,GYG2,C5,CLCN3,AKAP12,ARHGAP32,HDAC4,PARD6A,F8,SCML2,FHL1,NOP56,EFCAB2,TRMO,SESN1,GPD2,DHX35,LSS,NF1,NRCAM,PTCH1,ACSS3,PPP4R3A,ZHX3,SP2,SPTAN1,TACC1,FAM208A,IQCE,KIAA0930,KAT6B,VGF,PCBP4,SMIM8" Drug 1426_UP Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,ADORA2A,C1QTNF1,APOC1,CDK10,ARRB2,CFLAR,ARHGEF10,PPP1R16B,MRNIP,RASGRP2,STX2,OLFM1,PRKAG2,ERAP1,RUNDC3A,TXNL4A,BTN2A1,MAP4,PLEC,POLG,PPP5C,CEP41,PLPPR3,FERMT1,SLC11A1,MAPKBP1,FAIM2,FNBP1,ANKRD12,FAM208A,MGRN1,CA14,HIRA,PLPPR2,GJC2" Drug 2812_UP Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADRA1D,SEMA6A,APAF1,CACNA1I,HAP1,AKAP7,WHRN,RGS6,DAPK3,HEPH,MYEF2,HSD17B14,STX2,ETV1,DLC1,BAIAP2,GCNT2,GNAO1,GNG4,IRF8,GIT1,NF1,NTRK2,PPP5C,PRKCB,CRTAC1,RFX2,ZFHX4,KLHDC8A,TCP11L1,SEMA6D,PDZD2,SYP,SYT5,CABIN1,NT5M" Drug 2646_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "TRMT9B,SEMA7A,GAS7,DDO,SEMA4G,MARK4,RUNX1T1,ASIC3,SLIT2,COL9A3,LRIG1,RIMS2,PPP6R2,TMCC2,DMPK,EDN3,EDNRA,ERCC2,IQCG,SEPT9,PCDH17,GRM2,GUCY1A1,ATXN2L,IRF8,INPP5B,ITGA7,AFF1,PRPH,PREX2,HECW1,SPTAN1,TNS1,HIRA,PLPPR2,NDRG4" Drug 3757_DN Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,ADGRF5,AMPD3,ATP2A2,BMP7,SYNJ2,AP4M1,NRXN3,RAB26,SLC4A8,NRG2,HDAC9,LYPD1,FGFR1,CNTRL,SHISAL1,INPP5B,MAPT,CNOT4,PRKAR1B,SAMD9,RAD51D,RGS4,RBM34,ATP10B,TBCEL,TCF4,ZEB1,DNAH7,GPR161,TIAM1,TNS1,TRIO,HIRA,LAT2,TIGD6" Drug 2874_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SRPX,ALK,BEGAIN,CDC42BPA,GAS7,PPP4R4,CFLAR,CFAP410,CA4,SLC16A4,FHL5,TMCC2,DMPK,DNAH9,DUSP9,C3orf18,ZNF589,FGF1,PDLIM5,GLI2,PCLO,GUCY1B1,ICA1,IRF8,MSR1,TMOD2,CEP41,RPS6KA2,EMID1,KCNIP1,SH3BP2,SYT5,TMEM121,ZNF34,CABIN1,EVI5" Drug 3882_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AMT,APC,APLP1,APOC1,CDK10,ARHGDIG,CDK13,SYNJ2,SCAPER,HIP1R,DMPK,DTNA,DUSP9,PLXNC1,NCALD,EZH1,FYN,MAP2,PRKCB,RGS12,RASA3,FBXO11,FAM214B,BTBD7,ZKSCAN3,LIMCH1,SPTAN1,LHPP,PLCB1,SMG6,TNS2,TMEM121,THRA,PARD3,VIPR2,RNF170" Drug 4215_DN Zalcitabine [7481-89-2]; Down 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,MTUS1,BIN1,ABI3BP,SLITRK5,ARHGEF4,PPP6R2,RUBCN,USP6NL,COQ7,DENND4A,RRAGB,F8,TRMO,PDLIM5,FYN,AGFG1,SHISAL1,FAM69A,JAK2,MAPT,NDP,CCSER2,PTCH1,ZSCAN32,PTPRE,TMEM231,FAT4,ANKRD6,ZBTB43,IQCE,TRIM2,ZNF34,XRCC4,HPS4,MPPE1" Drug 2902_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADRA1B,BIN1,CDC14B,PRX,CACNA1G,CHN1,CNTN1,C2CD2,DZIP3,DAPK1,SPOCK2,KLHL3,CDON,FAM13A,ETV1,FER,FGFR1,FLT1,GAA,GFER,ZNF276,GRIK5,SYNPO,ITPKA,ADAM22,CEP41,TCP11L1,SEC14L1,PKNOX2,ARHGAP26,CDK19,TACR1,TBCEL,ZKSCAN5,KCNAB1,TIGD6" Drug 4216_UP Minoxidil [38304-91-5]; Up 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RGS9,NRP2,KSR1,BMP7,BAIAP3,MTMR7,ARHGEF2,DLGAP1,COL9A3,RIPOR2,SPOCK2,BRINP1,SGSM2,PLXNC1,AASS,ST3GAL6,PDLIM5,ZNF44,SIGLEC8,GLI2,GNAL,GRM8,ATXN2L,HNMT,ICA1,AFDN,ADAM22,PTCH1,SCN2B,FRMPD1,SNCA,IZUMO4,TACR1,TNS1,WIPF1,KCNK12" Drug 434_UP sodium 4-phenylbutyrate; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADD2,ADORA2A,PROM1,CACNA1I,RAB29,CHN2,CNTNAP2,PLPPR4,DRP2,EXTL2,FGF1,POMT1,FAM49B,DISC1,PTPRT,FAM69A,KCNJ5,KHK,MBP,PFKFB4,RETREG1,LRRN3,PTPRN,RASGRF1,GAL3ST4,GSTCD,ZFP30,SH3BP2,ASAP3,SPART,TCF4,KIAA0930,GPR161,TNS1,LAT2,GDPD5" Drug 2841_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NME5,ALCAM,BIN1,APLP1,BCAS1,SLC2A11,CA12,FOXN3,SPOCK2,SPOCK3,DMPK,HIPK3,FGFR1,FERMT2,STMN2,LMO2,TM6SF1,ADAM22,PCDH9,PFKFB2,PLCD1,MINDY2,PTN,RAD51D,C1orf54,GAL3ST4,ZFHX4,NLGN1,ZSWIM8,SYN2,DMXL2,DOCK9,TIAM1,TK2,ST7,RNF170" Drug 621_DN nocodazole; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,SHROOM2,MARK4,ATP2A2,TAOK2,RAB26,PPP6R2,C2CD2L,DMTF1,TUBD1,FAM49B,CGREF1,SESN1,GFER,DIDO1,CACFD1,AGBL5,FAM69A,IPO5,OCRL,MBOAT7,PPP3CA,RET,RIC8B,FUZ,FBXO11,ZNF430,ELMO2,USP33,CDK19,CEP68,MCF2L,OBSL1,PARD3,LMF1,MPPE1" Drug 5272_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SPARCL1,CDC42BPA,SYNJ2,CALB2,SLC16A4,FAM189A2,CNTN1,HS3ST2,DTNB,C3orf18,EPB41,RASGRP2,F5,PTK2B,FHL1,KHDRBS3,ZNF44,SRCAP,ADAMTS13,TJAP1,SMAD1,GIT1,CLDN11,CDK18,PFKFB2,SERPINI1,PTPRD,SEMA6D,NLGN1,KANSL3,PKNOX2,SLC11A1,SYN2,TLR4,TNS1,TRPM2" Drug 1787_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,ACTN1,NDRG2,ADORA1,APOC1,CNTN1,CPS1,CREM,NCOR1,CRYM,INTS1,DAPK1,MBNL2,ZNF589,IQCG,TRMO,ATP2C1,HSF2,LIG4,SCAMP5,GIT1,LRP12,MBOAT7,CNNM2,CRTAC1,DOK5,IQSEC2,ATP10B,THSD1,ST5,TACC1,CDH22,ZKSCAN5,VSNL1,ZNF189,HPS4" Drug 7428_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,ALCAM,DOC2A,MARCH3,EIF4G3,MPDZ,ST3GAL5,MTMR2,CACNA1I,KRIT1,LRRFIP1,RAB28,ENTPD4,SOCS5,DZIP3,C2CD2L,TMCC2,DMPK,DTNA,MRNIP,F8,MALT1,COPS8,POLL,RNFT2,MBD1,SETD4,ZSCAN32,RIPOR1,SNCA,SPART,STX1A,ANKRD12,HEY1,TRIO,UBE3B" Drug 6320_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,PKP4,APBB2,APC,APOC1,CDC14B,SCAPER,LDLRAD4,SYNGR3,WHRN,AATK,SUSD5,DUSP9,PLXNC1,MRNIP,STX2,BAIAP2,GPER1,GRIK5,GSTM5,ATXN2L,KCNN1,PALM,PFKFB2,CCSER2,PTCH1,PTPRE,KCTD17,TCP11L1,STUM,SH3BP2,KDM4C,CRTC1,TIAM1,LAT2,RNF170" Drug 3072_DN Rolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADORA2A,ADRA1D,FAM135A,PKP4,APC,MARK4,ADAM23,CFLAR,BMP7,SYNJ2,MYRF,HIP1R,SCARB1,FOXN3,ZNF337,KIAA0753,DTNA,EIF4G2,TNK2,RASGRP2,CD320,ZNF589,CAMKK2,SEPT9,PCLO,ACOT7,ZNF862,NRCAM,BEND5,AMBRA1,ZNF667,EXOC7,ADGRL3,PLPPR2,NPDC1,PHTF2" Drug 4403_UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,CFAP410,CACNA2D1,CAMK2B,CAST,LY86,NCOR2,DUSP9,RASGRP2,SPEG,ZNF589,FGFR1,CSPG5,GPR162,GRB10,CACFD1,ICA1,KCNH2,KIFC3,LAMA2,LSS,MID1,AFF1,NTRK3,PDPK1,PLXNB1,NECAB2,PPP5C,KCTD17,SCN2B,ASAP3,HKDC1,SLC11A1,OGDHL,ARHGAP26,ITM2C" Drug 3862_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADRA1D,AMH,APAF1,CDK13,CA4,CALB2,RAB28,CRY2,PDE4DIP,DMPK,ELN,HSD17B14,STON1,SPACA9,INPP1,MATK,MMP16,ADAM22,MYO7A,NPTX1,NTRK2,PCDH9,RELN,PTPRE,ENOX1,NEK11,EMID1,SLC6A8,UNC5B,TSPYL2,KIAA1107,CHST8,LAT2,ZFP37,EVI5,PLSCR4" Drug 4841_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,AMPH,BIN1,ADAM23,CFLAR,KSR1,CACNA1I,LDLRAD4,AKAP7,NECTIN3,SUSD5,CTH,RIMS2,EGFR,FGFR3,TJAP1,KIT,LIG4,TAGLN3,NEFM,PDE1C,PDE4A,PFKFB2,PRKAR1B,ZFP30,CCDC88A,KDM4B,ATP10B,DMXL2,PCDHGA10,DOCK9,PCDHA5,DICER1,R3HDM1,LAT2,TRIM9" Drug 1392_UP Pindolol [13523-86-9]; Up 200; 16.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AMT,APBA2,BMP7,MTMR3,SLIT2,PLAA,HINFP,SOCS5,CTH,DAPK1,FEM1B,MRNIP,EPB41L2,AGAP2,ATP2C1,LYVE1,NXPH3,KTN1,MARK3,MBD1,SETD4,PPM1B,MAPK10,CNNM2,PTX3,SATB1,SH3BP2,BTBD7,ZKSCAN3,SPART,LARP4,SS18,TTBK2,FAM208A,ZMAT3,VGF" Drug 6689_UP Biotin [58-85-5]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,APBB2,APC,ARHGDIG,ATP2B2,BMPR1B,SCAPER,CHN2,QKI,CRMP1,HAPLN1,LYPD1,DTNB,DUSP9,EDIL3,EDN3,EDNRB,HIPK3,MBNL2,EPB41,F5,REEP2,OLFM1,GRM8,PRKAR1B,ZMAT4,RNASEL,DZIP1,TROVE2,TACR1,DOCK9,AP4E1,ZNF24,ZNF225,EVI5,JPH3" Drug 6730_DN Rolipram [61413-54-5]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AMPD3,CDC14B,ARHGDIG,SCAPER,CACNA1I,PLEKHB1,PDE4DIP,CNTNAP2,SPOCK3,EXOG,AASS,ING4,ZNF589,ZNF44,B4GALNT1,SRCAP,POLL,TDRKH,GRM8,GUCY1B1,KCNN1,ZNF862,SERPINI1,PLCD1,GRAMD1C,PID1,FAT4,REV3L,ATXN7,LHPP,SAMSN1,RPGRIP1L,TIAM1,HIRA,EVI5,KCNAB1" Drug 1210_UP alpha-estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,CACNA1A,PLEKHB1,ARHGAP22,RAB28,ENTPD4,HAPLN1,CRY2,RUSC2,CDON,DPH1,FGF1,FGFR1,FYN,GNAL,PRRC2B,BTN2A1,GSN,GSTM5,MIA2,MX1,NF1,CLDN11,PTN,PID1,RGS4,ZNF671,TCP11L1,STUM,SUPT20H,HECW1,DDN,CABIN1,UGT8,CLIP2,SEMA3B" Drug 2910_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "PPP4R4,ATP6V0A1,MYRF,LDLRAD4,STOML1,COL9A3,CREM,CRYM,BRINP1,PARD6A,FAM13A,EBI3,MBNL2,ERBB2,EYA1,FCGRT,FGFR1,PRELID3A,ZNF44,GNG4,SPACA9,GSN,ADAM22,MSR1,ZNF862,NPR2,PDE4D,PLEC,CEP41,MAPK7,KLHDC8A,ZFP30,ST6GAL1,ARHGAP26,DBNDD2,SZT2" Drug 1491_DN Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,NDRG3,PPFIA3,ARRB1,ATP6V0A1,BCL7A,PDE4DIP,KIAA0586,RCAN1,OPTN,CDKL3,SYT17,TXNL4A,GNG4,TDRKH,ICA1,MIA2,NF1,NFYA,PRKAR1B,MAPK7,PRPH,TMEM104,RIPOR1,RAD51D,RNASEL,ABLIM3,KDM4B,PHLDB1,MCF2L,EXOC7,TBL1X,PARD3,NDRG4,GDPD5,AAAS" Drug 3642_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADORA2A,AP2A2,AMT,ARHGEF7,LDLRAD4,RUNX1T1,SLC16A4,CD86,SEPT7,ARHGEF6,BRINP1,EGFR,FGF13,FOXF2,GAD1,ALDH1L1,GPER1,PCLO,SMAD1,MAP4,MMP17,ADAM22,MX1,PCBP3,PDE4A,TMOD2,RELN,RGS12,EMID1,SPTAN1,SPTB,TBCEL,DOCK9,KCNAB1,ITM2C,ADAMTSL3" Drug 7417_DN Homochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,ARRB2,NCOA1,CAMK2G,LRRFIP1,SRSF11,TAOK2,LHX2,RAB26,PDE4DIP,GREB1,DCAF8,DTNA,FEM1B,IRAK4,IP6K2,INPP5K,MALT1,MUM1,NEK1,CNOT4,PPP5C,PRKAR1B,DCUN1D2,SUPT20H,FERMT1,EPN2,SIRT2,IFT122,ELOVL4,TRIO,ZBTB14,ZNF45,FIP1L1,UBE3B,GAN" Drug 5985_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SYT13,KCNAB2,APC,CACNA1I,CFAP410,CAMK2B,USP2,QKI,AKAP5,NCOR2,DCAF4,VPS13B,FGF1,FGFR1,NSG1,GNAL,PCLO,SHISAL1,KCNN2,AFDN,NFYA,NPR2,OPRL1,PDE4B,ENPP2,TMOD2,PLCD1,ZFHX4,KLHDC8A,PKNOX2,RGL1,GPR161,SLC44A1,AMACR,TRPM2,OSBP2" Drug 6488_DN Bacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,ALCAM,BIN1,EPB41L5,SEMA4G,PLA2G4C,ALDH7A1,CCNT1,BAG4,GIT2,DBT,JAKMIP2,PARD6A,DTNA,CNNM1,PDLIM5,FAM49B,GPR37,ITPKB,KCNH2,MAP4,MAPT,MID1,NF1,SLC11A2,MAPK7,KHDRBS2,ZC3H14,RPS6KA2,EMID1,SLC22A4,SS18,NXT2,HIRA,CLDND1,MPPE1" Drug 4978_DN Lovastatin [75330-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,BCL7A,CFAP410,CA12,CAMK2G,ARHGEF4,IRAK4,MRNIP,BAIAP2,INPP5K,SRCAP,RAB30,POLL,GRB10,CACFD1,BTN2A1,ITPKB,NEK1,NPR2,NPTX1,SETD4,LRP12,PRODH,RIPOR1,RGS3,PEX26,EPN2,LIMCH1,TBL1X,AP4E1,ZNF34,TK2,CABIN1,ZKSCAN5,ZNF45,MPPE1" Drug 1303_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "CDC42BPA,CDK10,SEMA4G,LDLRAD4,CLCN3,NRG2,CREM,MRNIP,CDKL3,AFF2,EFCAB2,CGREF1,POLL,ATXN2L,MAP4,NEFH,NPTX2,OGG1,PMP22,MAPK3,TMEM104,PTCH1,RET,SEMA6D,PEX26,SLC11A1,SPART,KANK1,SYT5,MCF2L,PDLIM2,OBSL1,CDK20,HIRA,VIPR2,NPDC1" Drug 1415_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ALCAM,HIP1R,ENTPD6,SOCS5,RUBCN,TM9SF4,DDX46,FEM1B,KCTD3,EPB41L2,ERCC2,DENND4A,VPS26C,EZH1,SEC23B,TRMO,STAU2,TRAF3IP2,DIDO1,NXPH3,KTN1,LAMP2,MBNL1,NFYA,PIK3R1,STRN3,LRP12,PPM1B,CNNM2,RDX,SATB1,CHD9,SPART,NXT2,CBX5,MPPE1" Drug 3433_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADD2,NME5,DOC2A,AMPD3,APBB2,PDE8B,RASL11B,SLC4A4,SCAPER,CAMK2G,ABI3BP,DAPK3,RCAN1,EDN1,EDNRA,MTSS1L,SCML2,ALDH1L1,GPER1,IPO5,KITLG,MMP16,POLG,MINDY2,PRKAR1B,ZDHHC14,KLHDC8A,ASAP3,FNDC3A,EXOC7,CRTC1,TK2,VGF,VIPR2,SPHK2,AP3B2" Drug 7416_DN Cortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APC,NUMB,ATP6V0A1,FOXN3,HOMER3,PDE4DIP,GREB1,RUBCN,DTNA,FGFR1,ANKFY1,CSPG5,ACOT7,HMGCL,FAM69A,MAPT,NEK1,NF1,CNOT4,KCTD15,PLEC,SLC25A23,VPS13C,TRAPPC13,FUZ,SYBU,SMARCC2,FNBP1,ZBTB43,TSPYL2,LHPP,EXOC7,KAT6B,KLC2,EVI5,SEMA3B" Drug 5110_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "GAS7,SLC4A4,FOXN3,CHN2,STOML1,VCAN,IGSF6,FGFR1,DISC1,LYVE1,HPGDS,GRM8,BACH2,AFDN,NOVA2,NTRK2,NTRK3,ABCB1,RETREG1,NECAB2,PPP5C,PTPRB,PTPRH,TMEM231,KHDRBS2,RPS6KA2,S100B,ZNF821,SLC8A1,SAMSN1,TACR1,PHF24,TK2,CABIN1,TPM2,VIPR2" Drug 1163_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "MARK4,NCOA1,N4BP2L1,ST3GAL5,CAMK2G,CNOT8,AKAP6,TBC1D5,RUSC2,FCF1,TNK2,EIF1,RASGRP2,RABEPK,F5,HTATSF1,LPAR4,MAP4,NLE1,SLC25A23,PPP5C,PTPRB,PTPRN2,TMEM231,SUSD4,KDM4C,UNC5B,CDK19,PLCB1,SIN3B,FLRT2,VIPR2,MAP3K12,KCNAB1,UBE3B,PHTF2" Drug 1464_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NME5,APBA2,BCAS1,SLC2A11,ATP6V0A1,ST3GAL5,SCAPER,CFAP410,CAMK2B,CBFA2T2,ASIC3,BAG4,GREB1,DCAF4,DMPK,EDNRA,IQCG,CINP,TDRKH,MAP4K5,KCNH2,MBD1,KITLG,PRODH,PTPRE,CHD9,SLC9A5,KDM4B,ELOVL4,ARC,MCF2L,TK2,BEX4,CDK20,WIPF1,SLC30A3" Drug 1633_DN "estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "CDC14B,ADAM15,BMP7,SYNGR3,SRSF11,FOXN3,TAOK2,SOCS5,APPL1,ARHGAP32,INTS1,C2CD2L,SUGP2,KAT8,POLR1B,FGFR3,INPP5K,GHR,GPR37,CNTRL,CLASRP,PACSIN2,KHK,MAN2A2,MAPT,NRCAM,FSD1,PPP5C,PRKAB2,FERMT1,PDZRN3,TSPYL2,CLASP1,LMF1,KLC2,ACTR3B" Drug 1688_UP Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AK2,BIN1,APBB2,PPP4R4,SLC4A4,GYG2,HAP1,FOXN3,B4GALT6,QKI,GPRASP1,PARD6A,NR1D2,MBNL2,ELN,ENO2,NCALD,BAIAP2,SPIN1,GNG4,GRIK5,ELOVL5,ADAM22,NF1,NNAT,NRCAM,NTRK2,PDE4A,RETREG1,PPP5C,PPP4R3A,SMARCA4,KDM4C,CHST8,ZNF34,PHTF2" Drug 1648_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,C1QTNF1,DOC2A,TRMT9B,FAM131A,MARK4,SLC4A4,BACH1,CFLAR,CA12,CNOT8,HOMER3,NCOR1,MFAP3L,LYPD1,TSPAN5,MBNL2,ZNF589,FAM49B,TXNL4A,MSL3,MAP4K5,GIT1,LYRM9,PALM,LRRN3,PTCH1,ZSCAN2,CCDC25,TCP11L1,RASA3,SH3BP2,PPP4R3A,UNC5B,VIPR2,CLIP2" Drug 5413_DN Methiothepin maleate [19728-88-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NME5,C1QTNF3,SEMA6A,CDC42BPA,APC,APLP1,ALDH7A1,C5,TAOK2,CNTNAP2,DOCK4,TBC1D5,GIT2,MAMLD1,KAT8,SEMA4D,OGA,SPACA9,KHK,IPO5,KITLG,NF1,RETREG1,NLE1,STRN3,MBOAT7,PRKAR1B,MAPK12,UNC5B,ST5,VPS13A,PLCB1,TNS2,AP4E1,EVI5,GDPD5" Drug 7243_UP Urosiol [128-13-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,MTUS1,NME5,SEMA4G,ARRB2,KIF1A,CHN2,TAOK2,NRG2,SLITRK5,DAPK3,EGFR,RABEPK,FCGRT,TRMO,POLL,PADI2,SHISAL1,MEF2C,SCAMP5,NF1,OCRL,MBOAT7,MAPK3,MAPK7,RGS4,SAFB,SBF1,FAM214B,ZNF667,SMARCD3,CABIN1,SSBP2,WIPF1,NT5M,SMIM8" Drug 2811_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "KIAA1324,BIN1,SLC4A4,BACH1,CAMK2G,FOXN3,ASIC3,TAOK2,DTNA,EDIL3,EDNRB,SPEG,OGA,NEU3,GFER,GLYR1,LILRA2,GRIK5,MID1,CLDN11,PURG,PTPRN2,PTPRO,RGS12,RPS6KA2,KCNIP1,RASA3,NLGN1,PREX2,ARC,ZEB1,PCDHA5,HIRA,LMF1,DNALI1,ITM2C" Drug 1513_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "CDC42BPA,APBB2,ADAM15,CAMK2G,SOCS6,RAB28,FAM189A2,SULT4A1,ARHGEF10,TMCC2,SUGP2,VPS26C,FGFR1,PRELID3A,MALT1,GLYR1,RAB30,GPR37,CACFD1,MITF,GIT1,NFYA,SLC11A2,CCSER2,FSD1,TCP11L1,SBF1,SH3BP2,KIF16B,ZHX3,ARC,TBL1X,CHST8,TPM1,UBTF,EPM2A" Drug 7399_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,APC,MPDZ,ST3GAL5,MYRF,CFAP410,CA12,B4GALT6,RCHY1,CNTNAP2,DZIP3,GPRASP1,TRAF3IP2,TMEM8B,COPS8,PRRC2B,SYNPO,JAK2,NF1,PCDH9,BCAS3,RIPOR1,RAD51D,ZNF671,SCN8A,SLC22A4,ST5,EXOC7,PARD3,TRIO,UGT8,VGF,XRCC4,NT5M,PHTF2,AAAS" Drug 4556_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "MTUS1,GAS7,PPP4R4,CDK13,AZGP1,LDLRAD4,TAOK2,CSF1R,DAPK3,EDN3,EDNRA,SEMA3D,ING4,OLFM1,AFF2,FYB1,RUNDC3A,GRIK5,PADI2,AFDN,MYCN,LYRM9,NF1,PDE4D,SLA,SLC2A5,SNCA,SPTB,SYP,TRIM2,ICAM5,TLR4,R3HDM1,TPM2,TUBB1,TIGD6" Drug 6097_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "LTBP4,BIN1,APLP1,APOC1,ARHGDIG,CDO1,VCAN,DGKB,HEPH,MYEF2,HS3ST2,CDON,TENM1,ELN,EFCAB2,FUT9,FYN,GATM,GCK,ALDH1L1,PRUNE2,GSN,HLF,MGAT3,KITLG,TAGLN3,CNOT4,PPP1R1A,PPP5C,PTX3,C1orf54,SCN2B,SLC11A1,PEG10,CLIP2,KCNAB1" Drug 1624_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,ADD2,C1QTNF1,APAF1,AQP6,RASL11B,ATP2A2,CFLAR,BMP7,CFAP410,CAST,CCNT1,KCNAB3,C2CD2L,DNM1,DTNA,EPB41L2,SPACA9,GSTM5,TJAP1,MX1,LYRM9,NF1,CCSER2,KCTD15,PLEC,LRP12,CNNM2,ATXN2,KDM4B,DMXL2,PHF24,TNS1,WBP2,NR2C2,SMUG1" Drug 7282_UP Meticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AMPD3,PDE8B,BAIAP3,LDLRAD4,RUNX1T1,B4GALT6,RCHY1,ABCG1,PDE4DIP,CNTNAP2,EXOG,EGFR,DENND4A,ANKMY1,F5,ZNF44,DENND2A,DISC1,POLL,GNAL,GUCY1B1,LSS,SCAMP5,NF1,STRN3,WDR25,ELOVL2,AMBRA1,ZHX3,SPTB,THSD1,ARC,EXOC7,SLC35G2,TIAM1,KCNK12" Drug 3045_UP Hymecromone [90-33-5]; Up 200; 22.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADGRF5,CDC42BPA,RGS20,RGS9,CFAP410,CALB2,USP2,CRLF1,SUSD5,CNTNAP2,SPOCK3,EDN3,EPB41,ZNF391,CORO2B,FLT1,SEPT9,NEU3,ZNF276,PCLO,GRIK5,RASSF8,HLF,C2orf72,LSAMP,MAP2,MYH3,NF1,PDE4D,BCAS3,ZFP2,ASAP3,SLC12A4,PCDHGB6,DOCK9,TK2" Drug 6384_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ALK,BIN1,GAS7,SCAPER,MYRF,VCAN,ARHGEF4,CYBB,SPOCK2,DBT,TMCC2,TENM1,EPHB1,DLC1,FYB1,SRCAP,PCDH17,RUNDC3A,GNG4,GPD2,ADAMTS13,HLF,KCNQ3,ADAM22,NPR2,NTRK3,TREM2,PDE4A,PLEC,DIRAS2,PTPRO,SYT5,TRIM2,ICAM5,TNS1,WIPF1" Drug 6346_DN Sulfasalazine [599-79-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,APLP1,SHROOM2,ARNTL,CA12,TBRG4,HAPLN1,DCAF8,SGSM2,DYNC1I1,TNK2,CINP,USP21,DENND2A,ERAP1,MAN1B1,MAN2A2,SLC11A2,CCDC25,SH3GL3,FUZ,ARHGEF40,CCDC88A,TMCC1,SPTAN1,EXOC7,TNS2,SLC35G2,TMEM121,CBX5,WIPF1,NDRG4,URM1,ST7,SMIM8,RNF146" Drug 6300_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,ASIC1,ADCY6,NME5,SEMA6A,PKP4,CA12,CACNA2D1,CHRNA4,ARHGAP22,LHX2,ABCG1,PDE4DIP,FAM131B,TOM1,EPHB1,FLT1,PRELID3A,INPP5K,ZNF276,PRUNE2,STON1,HSF2,IL6ST,MAN2A2,CLDN11,PFKFB2,ENOX1,SCN8A,ZNF821,ARHGEF9,TIAM1,BHLHB9,TNS1,UGT8,KCNAB1" Drug 6474_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,AK2,TRMT9B,BIN1,CFLAR,CACNA1I,CCNT1,B4GALT6,LHX2,PLAA,SLC4A8,ABI3BP,ENTPD4,DAPK3,MFAP3L,EDNRA,EGFR,EZH1,FHL1,CINP,OGA,MAP4,NEK1,SLC11A2,PLEC,ZDHHC14,FERMT1,NLGN1,TROVE2,ARC,THRA,FAM155A,PLPPR2,URM1,KAT6A,TIGD6" Drug 1733_UP Sulfasalazine [599-79-1]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,C1QTNF3,ARNTL,RAB29,WASF1,CD86,ARHGAP33,CLCN3,CNTFR,SEC31B,CSNK1G3,CST3,SEC14L5,GIT2,KLHL3,SEC23B,ATP2C1,GLYR1,LAMP2,MYT1,NEFH,NINJ2,NPTX1,OPA1,PLCB2,PTK2,PTX3,FBXW7,ATXN2,AMBRA1,ZC3H13,PBLD,KLHL7,PLCB1,SSBP2,RNF170" Drug 3026_DN Ioversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,PKP4,NCOA1,RIPK1,KIF1A,AZGP1,CACNA1A,CAMK2G,HIP1R,SCARB1,CLGN,SH2B1,TM9SF4,DTNA,TOM1,HIPK3,CELSR3,PDLIM5,KHDRBS3,LILRA2,NCKAP1L,ATXN2L,PPARA,WDR25,TRIM68,ZC3H14,ZNF671,CLIP1,RASA3,SPTAN1,KIAA1107,TCF4,SZT2,SSBP2,TRIM9,EMSY" Drug 7509_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APC,PDE8B,MARK4,ADAM23,BAIAP3,PLAA,ABCG2,CRY2,CSNK1E,CTH,SPOCK2,PITPNC1,FAM13A,COQ7,SYT17,GSN,AFF1,MX1,ZNF862,CLDN11,PFKFB2,FA2H,CNNM2,PID1,RAD51D,GSTCD,STUM,ZFP30,FNDC3A,UNC5B,TBL1X,SMG6,OBSL1,DNAH7,TPM2,VIPR2" Drug 3267_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,ALK,KCNAB2,MARK4,CFLAR,BMP7,CRLF1,UBE2L6,LHX2,DAPK3,RCAN1,EZH1,FER,FHL1,OGA,DISC1,FERMT2,GSN,KCNF1,KITLG,NF1,NPTX1,PPP5C,CEP97,RGS12,NEK11,EMID1,RASA3,SGK1,BTBD7,FNBP1,CEP68,CHST8,PARD3,VGF,EPM2A" Drug 3843_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "DOC2A,AMH,APBB2,MARK4,ARHGAP33,TAOK2,SIPA1L1,RIMS2,EXOG,DNM1,TNK2,FGFR1,GFER,USP19,HNMT,INPP1,ADAM22,NPR2,NTRK2,PLCD1,PLEC,SNRK,TMEM104,WDR25,ZSCAN2,ZMAT4,EMID1,BTBD7,SMARCD3,IQSEC2,TTBK2,RUNDC3B,VIPR2,KCNK12,XRCC4,EVI5" Drug 3390_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,CDC42BPA,N4BP2L1,AZGP1,BAIAP3,TAOK2,RAB33A,AKAP6,COL9A3,ARHGEF10,KLHL3,TNK2,MRNIP,FYN,GCK,ADAM28,GFER,GNG4,KCNJ5,TAGLN3,NF1,MASP1,PTPRD,C1orf54,ZMAT4,PNMA8A,SALL1,ST6GAL1,OGDHL,TSNAXIP1,UNC5B,ARHGAP26,SMG6,THRA,LAT2,SLC17A7" Drug 6019_UP Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ACHE,LTBP4,BEGAIN,APBB2,CBFA2T2,SOCS6,EPS15L1,COQ7,ERBB2,ERCC2,FGF1,FHL1,ALDH1L1,SRCAP,GNAO1,PRDM5,TJAP1,KCNH2,KCNJ5,MID1,AFDN,NOVA2,NPTX2,NTRK2,PFKFB2,SCN8A,ASAP3,SYBU,SLC22A4,FAIM2,HECW1,UNC5B,ZEB1,PCDHGB6,TFIP11,UBE3B" Drug 3880_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,APBB2,GAS7,CDK13,CBFA2T2,B4GALT6,WHRN,NECTIN3,DAPK3,ZNF804A,PLXNC1,HSD17B14,EZH1,SCARA3,GCNT2,TXNL4A,GSN,ATXN2L,IL6ST,KCNH2,LMO2,MAP2,MAP4,MIA2,MMP17,NF1,CNOT4,PRPH,ZSCAN2,CEP97,STX1A,TNS2,THRA,BHLHB9,FAM155A,SENP7" Drug 1853_DN Diprophylline [479-18-5]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,ANK2,APBB2,BCL7A,SYNJ2,KRIT1,SOCS6,OSBPL3,DTNA,SUGP2,FCGRT,SRCAP,TXNL4A,PADI2,MAN1B1,ATXN2L,JAK2,MAP4,MIA2,ZNF862,NINJ2,SETD4,P2RX7,PLCB2,POLG,PPP3CC,RET,FERMT1,AMBRA1,ZKSCAN3,SPTAN1,THRA,ZNF32,GDPD5,HPS4,PHTF2" Drug 2313_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG2,ADORA2A,APBA2,GAS7,CDC14B,RASL11B,KSR1,CACNA1G,CLGN,AKAP6,NRG2,HAPLN1,RASGRP2,ERBB4,FGFR1,CSDC2,POLL,GNAL,SOX21,LSS,MAN2A2,ADAM22,ZSCAN2,CXXC4,SOX3,HECW1,ZC3H13,DDN,ARC,ADGRL3,HIF3A,TNS1,TRO,FAM155A,ST7,ADAMTSL3" Drug 4530_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SEMA6A,BCAS1,CDC14B,PPP4R4,ARHGDIG,CDK13,ZSCAN18,ADGRB1,ADGRB2,MTMR3,RUNX1T1,ARHGAP33,NRG2,EIF4G2,ING4,ETV1,ZNF589,HPCAL4,SRCAP,NEFM,WDR25,PTPRN2,TMEM231,KANSL3,SLC9A5,ZNF334,SOX15,ZNF423,RBM26,ADGRL3,ZEB1,TRIM2,PCDHA3,TPM2,NT5M,KCNAB1" Drug 908_UP 5140203; Up 200; 15uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BRAP,APBA2,RASL11B,STX16,CFLAR,C5,ARHGEF2,CDH2,LRRFIP1,MAGI1,VAX2,RCAN1,DTNA,DUSP9,EIF4G2,IRAK4,F8,PDLIM5,HTATSF1,GPD2,CNTRL,SPACA9,INPP5B,LIG4,MBD1,MITF,SETD4,MINDY2,RNASEL,FNDC3A,SLC6A8,BTBD7,AP4E1,VLDLR,XRCC4,PHTF2" Drug 3439_UP Merbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABR,APBB2,APC,APLP1,APOC1,CDK13,ZBTB10,AKAP7,GREB1,DCAF8,JAKMIP2,RCAN1,KAT8,FHL1,IQCG,GALC,INPP5K,POLL,GPER1,MAN2A2,KITLG,PDE1C,PLEC,MINDY2,PTK2,RGS3,SYBU,FAM214B,BTBD7,SLC22A4,LIMCH1,ST5,PHLDB1,AGTPBP1,TMPO,LAT2" Drug 7302_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APC,CDC14B,STX16,CACNA1A,CHN2,HAPLN1,NCOR2,VCAN,DUSP9,EGFR,AASS,MTSS1L,ETV1,RRAGB,DISC1,GATM,TJAP1,SCIN,ADAM11,NDP,OPRL1,MBOAT7,PRPH,WDR25,PEX26,SNCA,PHLDB1,SYN2,ASTN2,TCF4,DNAH7,GPR161,SLC44A1,BEX4,CDK20,KCNAB1" Drug 5622_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "EP400,APC,FAM131A,PPFIA3,PDE8B,SYNJ1,SCAPER,CFAP410,ABI3BP,PDE4DIP,HIPK3,STX2,NCALD,RRAGB,MALT1,GLYR1,ICA1,INPP5B,KCNF1,LMO2,KITLG,CNOT4,NPTX1,LRP12,PRPH,KIF16B,ASAP3,FNDC3A,COA1,STX1A,PLCB1,CRTC1,CABIN1,ZNF711,PHTF2,SENP7" Drug 3314_DN Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,NME5,GYG2,CA4,CLGN,PPP6R2,RUSC2,RCAN1,CNNM1,FHL1,RUNDC3A,GLYR1,RAB30,ITPKB,KCNN2,MAN2A2,GIT1,NEK1,NF1,NPTX1,NLE1,TMEM104,ZSCAN32,FBXW7,MAP6D1,FAM214B,SLC6A8,SMARCD3,ERC1,UNC5B,NXT2,PLCB1,IQCE,EIF4ENIF1,VGF,SMIM8" Drug 4627_UP Altretamine [654-05-6]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APBB2,APC,PPP4R4,CA12,SOCS6,RAB28,STOML1,HAPLN1,CSF1,VCAN,PDE4DIP,CNTNAP2,C2CD2L,HIPK3,FCF1,ETV1,FYB1,GNG4,STON1,GPER1,GRIK5,PACRG,ADAM11,SCAMP5,MMP16,TAGLN3,CLDN11,PIK3R1,RETREG1,ANKRD6,SLC6A11,ZHX3,ARHGAP26,PHLDB1,TCF4,SLC44A1" Drug 4189_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADRA1D,APC,CDK10,ZSCAN18,BACH1,NRP2,MYRF,CA12,ARHGEF2,LARGE1,CHRNA4,RAB26,HOMER3,IPCEF1,PDE4DIP,EDN3,F5,CORO2B,LYVE1,GNAL,MARK1,MMP16,ADAM22,NTRK2,OPRL1,LRRN3,PRKAR1B,PTH1R,PTPRG,ENOX1,GAL3ST4,PBRM1,SLC6A8,ARHGEF40,DNALI1,SLC17A7" Drug 201_DN 15d-PGJ2; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADD2,ARRB2,ASPA,C5,CAMK2G,SCARB1,STOML1,HINFP,ARHGEF10,GREB1,SPOCK2,MRNIP,ERCC2,TRMO,SEPT9,ARFIP1,AGFG1,ICA1,PAXBP1,MAP4,MYT1,SETD4,CLDN11,PLCD1,PPM1B,TMEM104,EMID1,NUBPL,ABLIM3,SNCA,KDM4B,COBL,TRIM2,BHLHB9,R3HDM1,FLRT2" Drug 2888_UP Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SPARCL1,ALCAM,BIN1,CDC42BPA,GYG2,MYRF,CRLF1,TAOK2,CRMP1,SIPA1L1,DTNB,EGFR,CALCRL,HSD17B14,ERBB2,FYN,SRCAP,GLI2,ATXN2L,ZNF862,NPTX2,SLC25A23,RPS6KA2,BTBD7,SNCA,IQSEC2,ARC,EXOC7,KIAA0930,TMEM121,CABIN1,TRIO,FAM155A,UCHL1,ITM2C,ADAMTSL3" Drug 4722_DN Merbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SEMA6A,BCAS1,KIF1A,MTMR3,CBFA2T2,ARHGEF2,SLIT2,SH2B1,CRY2,ARHGEF4,DCAF8,DAPK3,EDNRA,CNNM1,AASS,HSD17B14,VPS26C,ACSL4,FYB1,TDRKH,INPP5B,KPNA5,MPP2,ZNF862,SLC11A2,TMEM231,FBXW7,FAM192A,ANKRD6,ARHGEF9,ZEB1,TRIM2,TRIO,ZKSCAN5,DNALI1,KAT6A" Drug 7012_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "GYG2,TPP1,ARHGEF10,SOCS5,MFAP3L,RCAN1,DTNA,ENO2,MTSS1L,EPHB1,FHL1,GAD1,LYVE1,GLYR1,RAB30,GPR75,LPAR4,CNTRL,GRM8,HNMT,MAP4,GPR85,SAMD9,C1orf54,ZNF821,ABLIM3,KANSL3,COA1,SNCA,ERC1,IQCE,NR2C2,AMACR,KCNK12,ZBTB14,NDRG4" Drug 6509_DN Halofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APLP1,CFLAR,GYG2,AP4M1,MAGI1,RAB28,AKAP7,FAM169A,ARHGAP24,B3GAT3,EXOG,STX2,DISC1,KCNH2,IPO5,MAP4,FAM184A,ZNF821,SH3BP2,FUZ,NLGN1,FAM214B,ZHX3,KDM4C,ZC3H13,SS18,NXT2,CEP68,KANK1,EXOC7,CDK20,VLDLR,XRCC4,ZNF24,EPM2A,ACTR3B" Drug 914_DN rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ACTN1,ADCY6,CDK13,CFLAR,SYNJ2,GYG2,SCARB1,RAB28,QKI,ENTPD4,APPL1,TBC1D5,DLC1,BAIAP2,NOP56,FAM49B,CAMKK2,CELF1,INPP5K,GHR,ZNF276,GPER1,BTN2A1,FICD,SLC11A2,RETREG1,PLEC,PMP22,PRKAR1B,MAPK12,USP33,TACC1,KIAA0930,KAT6B,PCBP4,PHTF2" Drug 3067_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASIC1,AMPH,APC,EPB41L5,PLA2G4C,DNAH17,CACNA1I,BAIAP3,TAOK2,SLIT2,CNTNAP2,RIPOR2,SV2B,CDON,SUGP2,NCALD,ALDH1L1,ZNF276,ADAMTS13,ELOVL5,ITPKA,MGAT3,GIT1,MTRF1L,MAPK7,GAL3ST4,RGS3,ZFHX4,SH3BGR,FRMPD1,ASAP3,SNCA,CLSTN2,PCDHA5,FAM155A,VGF" Drug 3706_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,ADGRF5,PPFIA3,CAMK2B,LARGE1,FOXN3,ARHGAP22,SH2B1,PDE4DIP,DAPK3,SPOCK3,DTNA,ING4,SPEG,FGF1,BAIAP2,EFCAB2,CINP,PRELID3A,RASSF8,MAPT,FSD1,CEP41,PRKAR1B,TCP11L1,ZNF821,ZBTB43,DDN,TBCEL,TIAM1,TRIO,ZNF24,VPS35L,PHTF2,DPF3,RNF146" Drug 6523_DN Deptropine citrate [2169-75-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "APC,PPFIA3,CDK10,ARHGEF7,C5,RAB29,SLC25A14,CACNA2D2,SRSF11,B4GALT6,RAB28,AKAP7,BAG4,PDE4DIP,GIT2,JAKMIP2,FBXL5,C2CD2L,EZH1,F8,TXNL4A,HNMT,LMO2,LYRM9,SYBU,EPN2,CLASP2,TTBK2,TACC1,MTCL1,EXOC7,XRCC4,ZBTB14,FTSJ1,HPS4,ACTR3B" Drug 4698_DN Mephenesin [59-47-2]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,AMT,CAMK2G,CBFA2T2,BAG4,NECTIN3,NCOR2,CSNK1E,BRINP1,EDNRA,AASS,SCML2,ZNF589,FHL1,CGREF1,GNG4,GRM8,BTN2A1,RASSF8,ITPKB,MPP2,ADAM22,NF1,RETREG1,MAPK7,SAMD9,ZDHHC14,BTBD3,SLC6A8,KIAA0930,ZEB1,PARD3,VGF,DNALI1,EVI5,MPPE1" Drug 144_DN chlorpropamide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SYT13,AMT,APBB2,GAS7,SLC4A4,ADAM23,ADAM15,BCL7A,CFLAR,CACNA1I,BAIAP3,ARHGEF2,UBE2L6,FOXN3,EPS15L1,SEZ6L2,SRPK3,TBC1D16,FLNC,NEU3,SRCAP,ZNF276,CACFD1,SCIN,MPP2,ADAM22,PALM,PRPH,GTDC1,FUZ,LIMS2,TMCC1,IQCE,PIK3R5,TRPM2,CA14" Drug 6788_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SPARCL1,KCNAB2,PRX,DNAH17,BAIAP3,EPS15L1,QKI,PPP6R2,RASSF2,JAKMIP2,DMPK,EDNRB,MBNL2,AGAP2,GLYR1,GRIK5,IPO5,LIG4,MAN2A2,KITLG,MPP2,ZNF862,NPTX1,PDE4D,RGS12,RNASE1,SUPT20H,SH3BP2,ASAP3,CNKSR2,STX1A,TBCEL,TK2,FAM155A,UCHL1,KCNK12" Drug 4378_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "RALGAPA1,ABHD6,KIAA1324,BIN1,APC,CDC14B,MARK4,CNTFR,WHRN,SH2B1,NCOR2,DMPK,MBNL2,PIPOX,PTK2B,ZNF589,OLFM1,SCARA3,DISC1,ATXN2L,ICA1,KHK,LYRM9,GRAMD1C,CCDC40,ZDHHC14,TRIM68,RASA3,SH3BP2,SNCA,CRTC1,TRPM2,UBE3A,PDIA2,VIPR2,ITM2C" Drug 6127_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ASPHD1,SEMA6A,FAM135A,BIN1,BMP7,RUNX1T1,SOCS6,FAM149A,DZIP3,MFAP3L,KLHL3,SV2B,OPTN,EIF1,RASGRP2,AFF2,KHDRBS3,HPGDS,NEFM,CNOT4,P2RY1,PCDH9,PGAM2,DUSP26,PLCD1,SLC25A23,PPP2R2B,PPP5C,CNNM2,ELOVL2,SLC11A1,TMCC1,DOP1A,PLCB1,PARD3,KLC2" Drug 2899_DN Ajmaline [4360-12-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "C1QTNF3,DOC2A,AMT,APBA2,APC,BCAS1,CREM,GREB1,DNM1,CNNM1,KAT8,FHL1,PDLIM5,TRAF3IP2,TJAP1,KHK,LSS,ADAM22,NTRK2,RETREG1,LRP12,PPP5C,PRKAR1B,SBF1,SUPT20H,SH3BP2,SYBU,ABLIM3,CXXC4,ZSWIM8,STX1A,TK2,RPRM,VGF,ZNF24,SMIM8" Drug 5943_DN rotenone; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BIN1,APBB2,PPFIA3,PPP4R4,SCAPER,CACNA1I,SULT4A1,CSF1R,MAML1,CDON,SLC12A6,INPP5K,GNAL,ICA1,IRF8,INPP5B,PACRG,TAGLN3,NTRK2,PTPRH,RAD51D,RGS12,SGK1,SNCA,CLSTN2,PHLDB1,ARC,ADGRL3,TBCEL,WSCD1,TRIM2,DICER1,ZKSCAN5,WIPF1,SPHK2,MAP3K12" Drug 5028_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ABHD6,AP2A2,BIN1,APBA2,FAM131A,CFLAR,CA4,CLGN,CSF1R,SIPA1L1,CNTNAP2,PPP6R2,SEC14L5,TBC1D5,KIAA0586,MAML1,CDON,COQ7,ZNF589,IQCG,MALT1,KCNJ5,KCNN2,NLE1,PLCD1,SH3BP2,KIF13A,ZHX3,LHPP,EXOC7,RUNDC3B,TSC2,KLC2,GDPD5,MPPE1,KAT6A" Drug 7280_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,GAS7,LGR5,SLC4A4,KRIT1,LHX2,RAB28,QKI,CSF1R,SOCS5,RUSC2,DTNA,E2F5,AASS,ACSL4,FLT1,TRMO,TMEM8B,SYT17,GPER1,MAN2A2,NF1,SLC25A23,LRP12,MAPK7,ROGDI,GTDC1,ZFP30,SMARCD3,TMCC1,ARHGAP26,ADGRL3,TK2,HIRA,WNT7A,XRCC4" Drug 4825_DN Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ADCY6,CDK10,MARK4,CFLAR,SCARB1,FAM189A2,PDE4DIP,ZNF337,JAKMIP2,SUGP2,EPB41L2,TXNL4A,GNG4,GRB10,MUM1,MAP4,MAPT,SCAMP5,MITF,ZNF862,NEK1,CCSER2,PLXNB1,PTK2,RIPOR1,NKAIN1,ZCWPW1,SAFB,SBF1,EPN2,SMARCA4,POGZ,PHLDB1,TACC1,IQCE,RUNDC3B" Drug 5304_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "NDRG3,NME5,AMPD2,BIN1,APLP1,STX16,ATP6V0A1,KYAT1,SRSF11,FOXN3,VAX2,HOMER3,SH2B1,PARD6A,FCF1,IRAK4,FGFR1,CACFD1,ATXN2L,MIA2,MPP2,SLC25A23,LRP12,PRKAR1B,PRODH,RASA3,SGK1,CHD9,CDK5RAP2,SPTAN1,THSD1,VPS13A,TACC1,TRIM2,SEMA3B,MPPE1" Drug 3305_DN Cisapride [81098-60-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AP2A2,ARRB2,NCOA1,NUMB,CFLAR,ARHGEF2,VAX2,ENTPD4,ABCG1,CSNK1E,LYPD1,BAIAP2,FAM49B,SRCAP,ZNF276,PRRC2B,CACFD1,GIT1,NPTX1,LRP12,ZSCAN2,ABLIM3,PREX2,SLC6A8,BTBD7,UNC5B,ELOVL4,STX1A,SUPT5H,TBL1X,ZNF34,TIAM1,KAT6B,PLPPR2,ZNF45,EPM2A" Drug 2743_UP Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "ALCAM,BIN1,APBA2,APOC1,EIF4G3,GYG2,CAMK2G,HOMER3,SH2B1,EGFR,EGR3,ING4,FHL1,NEU3,SLC25A23,PMP22,STRN3,REV3L,KCTD17,GSTCD,RPS6KA2,STUM,FBXO11,SPTAN1,CAMTA2,RGL1,TACC1,KIAA1107,CHST8,TRIO,UCHL1,ZNF45,ZNF74,NDRG4,MARCH8,KAT6A" Drug 7235_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "AK2,BIN1,CDC14B,ALDH7A1,MPDZ,NRP2,CA4,CACNB4,CALB2,ARHGEF2,TNK2,IGSF6,DLC1,SIGLEC8,TDRKH,GRM8,HNMT,ICA1,TJAP1,LIG4,ADAM22,NF1,CLDN11,PCDH9,NLE1,RGS12,SYBU,SLC2A5,FAM214B,RBM26,PHLDB1,ARC,TRIO,AMACR,XRCC4,SENP7" Drug 5524_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "SRPX,APBB2,MARK4,CFLAR,SYNJ2,SLC25A14,SIPA1L1,SOCS5,PDE4DIP,TM9SF4,GIT2,SPATA2,SGSM2,CDON,MAMLD1,ERBB2,DLC1,FHL1,TRAF3IP2,GAD1,AHDC1,TDRKH,LMO2,NF1,OCRL,LRP12,SUSD4,CLIP1,FERMT1,FUZ,BTBD7,ASTN2,SLC44A1,PARD3,PLPPR2,MPPE1" Drug 1802_DN Panthenol (D) [81-13-0]; Down 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "C1QTNF1,APOC1,MARK4,PLEKHB1,EPS15L1,ARHGEF6,WHRN,DAPK3,RUSC2,EIF5,FGFR1,BAIAP2,SYT17,DISC1,FERMT2,GPER1,MX1,SETD4,OGG1,MBOAT7,TMEM104,ELOVL2,MCMBP,MAPK12,ASAP3,FUZ,LIMS2,SIRT2,IFT122,FNBP1,STX1A,IQCE,FAM155A,EIF4ENIF1,HPS4,SMIM8" Drug 1135_DN minocycline; Down 200; 10.5uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.92E-03 1.00E+00 1.89E-02 2.13E-01 36 198 "BRAP,ARRB2,ADAM15,AP4M1,LRRFIP1,EPS15L1,PPP6R2,RUBCN,SGSM2,MED12,RCAN1,VPS26C,SCML2,INPP5K,MALT1,GRB10,CACFD1,KIF2A,MAPT,MYO5A,NRCAM,CCSER2,KCTD15,MAPK3,PBRM1,DCUN1D2,SAFB,ARFGAP1,SP2,SS18,NSFL1C,TSC2,ZNF45,ZBTB38,JMJD1C,LAS1L" Drug 3141_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-03 1.00E+00 1.90E-02 2.14E-01 30 157 "ABHD6,MTUS1,BIN1,DNAH17,CD86,CD38,CHN2,WHRN,CREM,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,FAM13A,PRKAG2,PDE4B,PDE4D,SERPINI1,SMOX,NECAB2,QDPR,TMEM255A,SATB1,GALNT10,SGK1,ARHGEF40,SPTAN1,PLCB1,TRPS1,FLRT2" Drug CID000004507 nitrendipine Stitch 2.95E-03 1.00E+00 1.91E-02 2.15E-01 21 98 "ADCY8,AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CACNA2D2,ABCG2,EDN1,EDN3,EDNRA,MAP4K5,HBA1,ABCB1,PKD1,RYR3,TPCN2,SLC30A4" Drug CID011947681 nitroprusside Stitch 3.02E-03 1.00E+00 1.95E-02 2.20E-01 23 111 "RALGAPA1,ADCY6,AGT,ALDH7A1,CACNA2D1,CBS,CNTN1,CTH,DMPK,NR1D2,EDN1,EDN3,F5,BRD8,GUCY1B1,NPR2,NPTX1,NPTX2,PDE3A,MAPK3,SLC12A2,PEG10,TLR4" Drug ctd:D014284 Triiodothyronine CTD 3.09E-03 1.00E+00 2.00E-02 2.25E-01 75 483 "ADD2,ADORA1,ADRB2,AMH,TMEFF1,NCOA1,ATP2A2,ADAM15,HCN2,BMP7,CALB1,ARHGEF25,CBS,CCNH,ZBED1,TMEM184B,SULT4A1,IGLON5,FAM171B,AKAP12,NCOR1,NCOR2,CTH,HDAC9,ZNF337,DMPK,PLXNC1,SLC43A2,ZNF461,TUBA1B,FDFT1,FGF1,FGFR1,FGFR3,MEX3B,POMT1,DLL3,GATM,GCK,PPARGC1A,TTBK1,GLI2,RAB30,AIFM3,GRIK4,BTN2A1,HBA1,MIER3,IGF1,ITGAM,LSS,MBP,ADAM11,ADAM22,LYRM9,NEFM,NFIX,PCSK1,SMOX,POLG,PPARA,MAPK3,DPF2,HUNK,SHMT2,SLC2A5,EPC1,PEG10,TRIM2,SIRT1,THRA,HIRA,VLDLR,LGI4,TIGD6" Drug 2685_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.11E-03 1.00E+00 2.01E-02 2.26E-01 33 178 "CLK4,SEMA7A,ATP6V0A1,KALRN,CREM,RGS6,SIPA1L1,PDE4DIP,ZNF337,MYEF2,FAM13A,MBNL2,AASS,SRPK3,PRKAG2,OGA,GCNT2,STON1,PACRG,NTRK2,PDE4B,PMP22,MBOAT7,POLG,PRKACB,HSPA4L,ZNF415,IZUMO4,SYT5,TIAM1,TRO,ZBTB38,FXR1" Drug 5779_UP Ellipticine [519-23-3]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.11E-03 1.00E+00 2.01E-02 2.26E-01 33 178 "LGR5,RASL11B,SLC4A4,SLC16A4,RAB33A,SH2B1,MFAP3L,PLPPR4,EDIL3,EDN1,EGR3,CSPG5,SYT17,GNAL,LAMA2,NEFM,NEFH,NPTX1,NPTX2,PALM,PCDH9,LRRN3,PTCH1,ENOX1,GAL3ST4,RGS4,PNMA8A,RPS20,KCNIP1,SGK1,SOX11,ARC,DPF3" Drug 4688_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.14E-03 1.00E+00 2.02E-02 2.27E-01 34 185 "DOC2A,APBA2,MARK4,CA12,ARHGEF2,QKI,GREB1,RHOBTB1,EDNRA,RASGRP1,EGR3,COQ7,FGFR1,SYNCRIP,GAD1,INPP5K,MSL3,JAK2,ADAM22,PIK3R1,RETREG1,SMOX,LRP12,PTPRE,RAD51D,SGK1,ARC,IQCE,HIRA,VGF,VLDLR,XRCC4,NDRG4,REEP1" Drug 1673_DN Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.14E-03 1.00E+00 2.02E-02 2.27E-01 34 185 "CDC42BPA,BCL7A,CFLAR,CCNT1,TBC1D5,NR1D2,FCF1,PCYOX1,CRCP,SPIN1,MAP4,MIA2,MITF,MMP16,MYO6,NPR2,PIK3R1,TMEM260,SLC25A36,SEC14L1,ERC1,ZBTB43,CEP68,PRRC2C,ANKRD12,TBL1X,DICER1,TMPO,KAT6B,ZNF24,ZBTB38,SLC38A1,MPPE1,FXR1" Drug 2551_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.14E-03 1.00E+00 2.02E-02 2.27E-01 34 185 "NDRG2,AMH,DDO,PTCH2,SLC4A4,PROM1,CACNA1G,CACNA2D1,CAPN3,USP2,EPS15L1,CNTFR,NCOR2,DZIP3,RIPOR2,EXOG,DTNB,EDN3,FAM13A,CDKL3,GAD1,GSN,MMP16,FXYD1,PTPRN2,ZFP2,ASAP3,IZUMO4,ZC3H13,SAMSN1,ARHGEF9,DNMBP,CRTC1,TUBB1" Drug 2686_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.14E-03 1.00E+00 2.02E-02 2.27E-01 34 185 "CACNB4,ARHGAP33,CRLF1,BAG4,CREM,CRYBB1,SIPA1L1,PDE4DIP,USP6NL,FAM13A,MBNL2,AASS,FYB1,GSN,HNMT,MMP16,ADAM22,NEFM,PDE4B,MTRF1L,SEPT4,MBOAT7,PRKACB,SUGCT,HSPA4L,ZNF415,AP4E1,TIAM1,TK2,RIMBP2,FAM155A,KCNK12,ZBTB38,ZNF225" Drug CID000031645 pirimicarb Stitch 3.14E-03 1.00E+00 2.02E-02 2.27E-01 13 50 "ACHE,SLC4A4,BCHE,CACNA1A,LARGE1,CS,BOC,DTNB,ICA1,PTPRN,RBBP8,ATXN7,TBL1X" Drug 1076_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "EPB41L5,ARNTL,CDK13,NCOA1,BCL7A,CFLAR,SYNJ2,CLCN3,RAB26,MFAP3L,FBXL5,MED12,DTNA,TSPAN5,MBNL2,CDKL3,IP6K2,FAM49B,B4GALNT1,MUM1,MAP4,AFF1,PMP22,STRN3,PPP3CC,ZNF821,SUPT20H,AMBRA1,ABLIM3,ARFGAP1,SMARCC2,RCOR3,CLSTN2,TRIM2,TPM1" Drug 464_DN WY-14643; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "AP2A2,ADAM23,MYRF,CHN2,WHRN,CPS1,ENTPD4,GIT2,RCAN1,SUGP2,EGFR,C3orf18,FCGRT,NEU3,GPER1,GPR37,CACFD1,KIFC3,NPTX1,PCDH9,SNX10,ZSCAN32,PTX3,SAFB,ATXN2,ZNF821,AMBRA1,SPTB,ITPRID2,PHLDB1,GPR161,LMF1,ZNF189,MPPE1,AAAS" Drug 3123_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "MTUS1,BIN1,CBFA2T2,SCARB1,ENTPD6,HOMER3,SEC31B,CSNK1E,TM9SF4,INTS1,SPATA2,PCOLCE2,COQ7,PTK2B,CGREF1,SEPT9,AHDC1,COPS8,SLC2A6,NRCAM,NLE1,PLCD1,PLEC,PILRA,TMEM231,RET,ARFGAP1,VPS13A,EXOC7,TCF4,R3HDM1,CABIN1,ZKSCAN5,UPF3A,MARCH8" Drug 4462_DN "ICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "APC,CDK10,MARK4,ADGRB2,MTMR3,CNTN1,COL9A3,CREM,ARMCX2,DNM1,FGF1,ATXN2L,LSS,KITLG,MX1,NF1,PFKFB4,PLCB2,PLEC,SUGCT,ASAP3,SIRT2,IQSEC2,DDN,LHPP,SAMSN1,EXOC7,SMG6,GPR161,TIAM1,PLPPR2,ZNF711,ZNF74,SH3GLB2,EPM2A" Drug 2846_UP Trimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "ALCAM,ALK,BEGAIN,APOC1,CFLAR,BMP7,ARHGAP33,MAGI1,PDE4DIP,EXOG,ERCC2,VPS26C,FAM49B,SLC2A6,ICA1,IL6ST,INPP5B,LMO2,PLCD1,MBOAT7,MINDY2,PRKAR1B,RGS12,SLC25A36,ZBTB43,ARHGEF9,TMEM121,CDK20,TRIO,HIRA,PDIA2,LMF1,SLC30A3,EMSY,GDPD5" Drug 5456_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "C1QTNF3,APBB2,CDC14B,PDE8B,BAIAP3,CBFA2T2,CLGN,PLEKHB1,PLAA,ANKMY1,FER,DISC1,INPP5K,COPS8,GPER1,CNTRL,MATK,ADAM22,ZNF862,NF1,CNOT4,PLEC,EMID1,SBF1,ZNF821,LIMCH1,SPART,EXOC7,SLC44A1,REEP1,ZNF189,GDPD5,SEMA3B,EPM2A,SENP7" Drug 6164_DN "aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "APAF1,KCNAB2,NCOA1,STX16,CFLAR,SCARB1,SOCS6,IQCK,CSF1R,ZFYVE16,RCAN1,DTNA,COQ7,VPS26C,GLYR1,GSN,MAP4K5,ELOVL5,TJAP1,IL6R,INPP5B,MAP4,PIK3R1,PLCB2,LRP12,RETREG2,MSANTD2,GTDC1,BTBD3,SLC11A1,SS18,ANKRD12,TMPO,ZKSCAN5,HIRA" Drug 4217_DN Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "MTUS1,SHROOM2,B4GALT6,SMARCAL1,SLITRK5,SNPH,TBC1D5,GIT2,ZBTB24,RHOBTB1,DENND4A,F8,DENND2A,GPER1,HNMT,FAM69A,LIG4,TM6SF1,MIA2,NDP,PLCD1,PTCH1,PTN,ZSCAN32,PTPRE,AP1AR,FBXO11,ANKRD6,GLT8D1,FAM208A,TNS1,XRCC4,HPS4,KCNAB1,PLSCR4" Drug 1174_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "ASIC1,AP2A2,ATP6V0A1,SYNJ2,SLC16A4,ARHGAP33,CNOT8,SULT4A1,CREM,SIPA1L1,PDE4DIP,B3GAT3,EIF1,RASGRP2,DCTN2,GSN,MYCN,PDPK1,CCSER2,PPP5C,VPS13C,PTK2,PTN,ZNF493,RGS3,FNDC3A,ZNF415,EXOC7,SZT2,HIRA,FLRT2,LMF1,REEP1,GDPD5,PHTF2" Drug 6808_DN Estropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "NDRG2,MTUS1,APC,SYNJ2,FOXN3,ASIC3,VAX2,ARHGEF6,BAG4,CSF1R,FAM169A,RIMS2,SLC12A6,EIF4G2,ING4,TNK2,GNG4,IL6ST,KPNA5,MAPT,STRN3,PPP5C,PRPH,RGS3,RGS12,NEK11,CNKSR2,PREX2,ZKSCAN3,SNCA,SAMSN1,STX1A,PLCB1,TBL1X,EPM2A" Drug 7526_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "SEMA4G,C5,CNOT8,AKAP12,NCOR2,CTH,CNNM1,FRY,EGFR,DCTN2,GCNT2,CACFD1,DHX35,LSS,MIA2,MKLN1,NFYA,ZNF426,PTPRH,PTPRN2,PID1,ZDHHC14,RGS4,PPP4R3A,FAM214B,BTBD7,SS18,CEP68,VPS13A,UGT8,OSBP2,ZBTB14,ZNF225,EVI5,SMIM8" Drug 7062_UP GW8510; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "ACTN1,ALCAM,SRPX,KCNAB2,APOC1,KIF1A,BMP7,CA4,CAMK2B,CAMK2G,RHBDL1,CNTFR,CRY2,CSF1,CD320,F5,FHL1,PDLIM5,GALC,ERAP1,USP19,GLYR1,LYRM9,NF1,NPR2,SLC25A23,MTRF1L,IQSEC2,ST5,ZMAT3,UPF3A,GDPD5,SEMA3B,URM1,KCNAB1" Drug 5990_DN Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.17E-03 1.00E+00 2.02E-02 2.27E-01 35 192 "ASPHD1,APC,PPFIA3,PDE8B,CFLAR,SYNJ2,SCAPER,C5,AKAP7,NCOR1,PDE4DIP,FAM169A,GREB1,ANKMY1,KAT8,FGFR1,FHL1,IL6R,SLC25A23,PRODH,SAMD9,PTK2,TMEM231,SUSD4,RXRA,PPP4R3A,ZHX3,IQSEC2,ASTN2,CHST8,LMF1,XRCC4,ZFP37,MAP3K12,HPS4" Drug ctd:D010622 Phencyclidine CTD 3.18E-03 1.00E+00 2.02E-02 2.27E-01 19 86 "ADORA2A,CALM1,CAMK2A,CAMK2B,SCARB1,FDFT1,GABBR1,CPLX2,MBP,KITLG,P2RY1,RELN,RGS4,KCNIP3,SGK1,ARHGEF9,SYN2,SEMA3B,RTN4" Drug 6491_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABHD6,AK2,C1QTNF3,BIN1,APC,CREM,DZIP3,DOCK4,DCAF8,DAPK3,SGSM2,EDNRA,EGFR,MRNIP,EPB41L2,FGFR1,DISC1,KCNMB4,CNTRL,SPACA9,GRIK5,JAK2,ZNF862,NF1,SETD4,PPP5C,ELOVL2,ZDHHC14,SYBU,BTBD7,SOX3,ZC3H13,RPGRIP1L,HIRA,PLPPR2,LMF1" Drug 2498_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BEGAIN,AMPD3,PKP4,SEMA4G,ARHGDIG,CACNA1I,CACNA1G,SCARB1,CDH2,RAB26,CREM,RIMS2,DBT,EXOG,EDNRA,HIPK3,APC2,AGAP2,CAMKK2,GATM,LILRA2,JAK2,KCNN1,NF1,NINJ2,NPR2,PDE4A,PDE4D,PPARA,PTH1R,RFX2,TCP11L1,LIMS2,DOCK9,CABIN1,SLC17A7" Drug 5014_DN Bemegride [64-65-3]; Down 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ALCAM,AMT,PLA2G4C,SLC4A4,CFLAR,ARHGEF7,CLGN,RIMS2,GPRASP1,DAPK3,MFAP3L,DNM1,DPH1,SUGP2,ING4,FER,FGFR1,SRCAP,CACFD1,TJAP1,IL6ST,KCNN2,MSI1,ZNF862,PLCD1,PPP2R2B,SBF1,CPEB3,FAM214B,LIMCH1,TSPYL2,PHLDB1,EXOC7,PCDHA6,ZNF34,XRCC4" Drug 2132_DN Xylazine [7361-61-7]; Down 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "MARK4,SYNJ2,SCARB1,ENTPD6,TAOK2,VCAN,ARHGAP32,SGSM2,SUGP2,ING4,PCOLCE2,PDLIM5,TRAF3IP2,ADAM28,KCNJ5,P2RY1,PDPK1,PLCB2,RETREG2,MINDY2,PRKAB2,RXRA,ZNF821,KDM4B,SPATA7,RBM26,DNMBP,TBL1X,TCF4,SZT2,R3HDM1,PARD3,TNS1,ZNF142,REEP1,KAT6A" Drug 5695_DN S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,ARRB2,FUBP1,CA4,CA12,B4GALT6,DCAF8,GIT2,RUSC2,IRAK4,ANKMY1,FGFR1,IQCG,ANKFY1,GALC,MALT1,GLYR1,ITPKB,KCNF1,KHK,LMO2,KITLG,MMP16,MPP2,LYRM9,NF1,CNOT4,SLC25A23,SNRK,TMEM104,ELOVL2,GTDC1,RPS6KA2,FERMT1,RPGRIP1L,ZBTB14" Drug 4_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 1000uM; MCF7; HG-U133A" Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,GAS7,SYNJ2,MTMR2,SCARB1,CD38,PICK1,NCOR2,PDE4DIP,INTS1,ARMCX2,ING4,FGFR1,POMT1,RASL10A,ATP2C1,RUNDC3A,GRM8,NCKAP1L,HSF2,KCNJ5,LAMA2,MBP,ADAM22,NELL2,NF1,NNAT,NTRK3,C19orf57,PTH1R,PTPRN2,SSTR2,TBL1X,OBSL1,TNS2,PARD3" Drug 7418_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,ASIC1,ADCY6,PPFIA3,CFLAR,MTMR2,CA12,ARHGEF2,SOCS6,ENTPD4,HDAC4,C2CD2L,HIPK3,EGR3,EIF4G2,HSD17B14,CDKL3,SEPT9,MSL3,RNFT2,RASSF8,KCNF1,KHK,MAP4,MIA2,ZNF862,NF1,SETD4,PRPH,PTN,ZSCAN32,RIPOR1,SLC2A5,CHST8,TRPM2,ZBTB14" Drug 590_DN 3-aminobenzamide; Down 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "OGT,APAF1,APBB2,APOC1,CDC14B,ARNTL,CFLAR,ARHGAP33,CNOT8,NCOR1,DRP2,EPB41L2,ZMYND10,PRKAG2,PDLIM5,NEU3,SRCAP,GRB10,PTPRT,ATXN2L,IGF1,ITPKB,NF1,STRN3,PTPRE,RASGRF1,RXRA,SH3BP2,SLA,SMARCC2,INTS9,SEPT8,SIRT1,TP53BP1,VAV1,ADAMTS9" Drug 2057_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP4M1,CNOT8,TAOK2,SH2B1,VCAN,PPP6R2,ARHGAP32,SNPH,TM9SF4,RUSC2,MED12,SLC12A6,MAMLD1,ZNF589,POLR1B,GAD1,PRRC2B,DIDO1,ACOT7,AGFG1,MPP2,SETD4,NLE1,ZNF426,SUGCT,SBF1,ATXN7,ZKSCAN3,ZNF415,POGZ,EXOC7,MGRN1,TRIM2,UBTF,MPPE1,ACTR3B" Drug 5541_DN Mometasone furoate [83919-23-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,C1QTNF3,APC,MARK4,STX16,RIPK1,BCL7A,CFLAR,TAOK2,NECTIN3,NCOR1,ABCG1,GREB1,MFAP3L,MED12,CNNM1,MRNIP,DLC1,FGF12,FGFR1,FHL1,ATP2C1,ZNF44,AHDC1,ZNF276,BTN2A1,RNFT2,ICA1,ITPKB,LMO2,GIT1,FUZ,PPP4R3A,RBM34,ZBTB43,ZBTB14" Drug 4571_UP Levodopa [59-92-7]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "TRMT9B,ZSCAN18,MTMR3,CBS,CRLF1,ABCG2,CREM,CNTNAP2,MAML1,MFAP3L,TENM1,MTSS1L,ANKMY1,FGFR3,SEPT9,MSL3,CACFD1,KPNA5,PALM,PDE4D,PIK3R1,PLCD1,MINDY2,PTCH1,PTN,FBXW7,CPEB3,SLC11A1,DOK5,SPTB,ZBTB43,PHLDB1,SMG6,TIAM1,ZNF24,SEMA3B" Drug 4840_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1D,AMPH,APBA2,APC,PDE8B,MTMR3,CACNA1G,BAIAP3,CLGN,PICK1,NRG2,CRMP1,HAPLN1,RIMS2,DBN1,MFAP3L,EGFR,C3orf18,DCTN2,DISC1,GNAO1,GRB10,C2orf72,LMO2,LSS,NNAT,SERPINI1,POU6F1,PPP2R2B,ZSCAN2,ENOX1,FRMPD1,CNKSR2,SNCA,PEG10,NXT2" Drug 1003_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "KRIT1,NECTIN3,CRY2,NCOR1,HDAC4,GIT2,DBT,FBXL5,PARD6A,SGSM2,ING4,MRNIP,COQ7,FER,OGA,FYN,TXNL4A,HTATSF1,GRB10,HNMT,AGFG1,INPP5B,NEK1,PDCD2,PLEC,PRKAB2,APTX,DCUN1D2,ZBTB43,ELOVL4,DIP2A,ASTN2,PDLIM2,IQCE,ZNF45,SMIM8" Drug 3341_DN Reserpine [50-55-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "APBB2,CDK10,SLC4A4,CRY2,PPP6R2,DCAF8,MAML1,DTNA,EIF5,ING4,BAIAP2,TRMO,CACFD1,BTN2A1,IL6ST,MMP16,NF1,CNOT4,PPP5C,PTN,RET,RPS6KA2,SUPT20H,ABLIM3,SLC6A8,BTBD7,TMCC1,RBM34,THSD1,PHLDB1,PCDHA6,TMEM121,TK2,HIRA,ZNF23,EVI5" Drug 5006_DN Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,NME5,SRPX,APBA2,APOC1,SGSM2,E2F5,CNNM1,ACSL4,RACK1,FGFR3,SEMA4D,TDRKH,GRB10,HNMT,ITPKB,ADAM22,NF1,CNOT4,PRODH,WDR25,SH3BP2,PEX26,SPTAN1,TTBK2,EXOC7,IQCE,RPGRIP1L,CHST8,TP53BP1,FAM155A,VGF,KLC2,HPS4,MPPE1,KAT6A" Drug 3036_UP Aminophylline [317-34-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC42BPA,FUBP1,HAP1,SOCS6,STOML1,AATK,CNTNAP2,RIPOR2,C2CD2L,EGFR,EPB41,SIGLEC8,ZNF276,GNAL,LILRA2,PCLO,GUCY1A1,NPY,PDE1C,POU6F1,MAPK10,CNNM2,ACSM5,MAP6D1,PREX2,TMCC1,KDM4B,IZUMO4,PEG10,CDK19,TACR1,SMG6,ZFPM2,ZNF34,LMF1,KCNK12" Drug 7016_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AK2,SEMA6A,SRPX,DOC2A,BIN1,CDC14B,RGS9,SCAPER,LDLRAD4,CA4,CAMK2B,LRRFIP1,PLEKHB1,TAOK2,ZNF589,BAIAP2,SCARA3,GFER,ADAMTS13,GRIK5,SLC2A6,HLF,MAP4,GIT1,NF1,LRP12,SAMD9,RIPOR1,SCN2B,PEG10,WSCD1,KIAA0930,TPM1,VIPR2,LMF1,WIPF1" Drug 7308_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AK2,APBB2,ATP2B2,ALDH7A1,SYNJ2,CA12,CBFA2T2,SOCS6,QKI,CRY2,HDAC9,EDIL3,CSPG5,GAD1,DISC1,ALDH1L1,GPER1,ATXN2L,IFI16,MYO6,NF1,PDE1C,KCTD15,ZSCAN32,ACSS3,CCDC40,ASAP3,SNCA,ZHX3,ZBTB43,ATP10B,THSD1,TBCEL,RPGRIP1L,CRTC1,XRCC4" Drug 4823_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "APC,LDLRAD4,SRSF11,TPP1,STOML1,ENTPD4,PDE4DIP,CNTNAP2,DZIP3,TBC1D5,GIT2,MFAP3L,ING4,RRAGB,ATXN2L,IL6R,JAK2,LIG4,LSS,MAN2A2,MSR1,NEK1,NPR2,PALM,ZNF493,NEK11,KDM4B,IQSEC2,SAMSN1,SMG6,PCDHA5,CABIN1,XRCC4,SH3GLB2,SLC30A3,JMJD1C" Drug 2461_UP Iohexol [66108-95-0]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "APC,CDK10,GYG2,BAIAP3,CDH2,CREM,SIPA1L1,PDE4DIP,ANKMY1,SIGLEC8,SRCAP,AHDC1,GNG4,ATXN2L,HNMT,KCNN1,MID1,MMP16,MYO6,NRCAM,WDR25,RGS12,ZFHX4,PNMA8A,SH3BP2,SLC11A1,LIMCH1,SOX15,IZUMO4,SEPT8,RPGRIP1L,THRA,CHST5,AMACR,LMF1,KAT6A" Drug 5968_UP H-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AMT,ATP1A3,ATP2A2,ARHGAP33,RAB26,PDE4DIP,CNTNAP2,RUSC2,SPOCK3,EGFR,FLT1,EFCAB2,CINP,NSG1,GRM8,ELOVL5,IL6ST,KCNH2,KCNJ5,NF1,PALM,GPR85,PTN,SLC6A8,SNAP25,SPTB,CDK19,DDN,ATP10B,ASTN2,VIPR2,WIPF1,MAP3K12,UBE3B,PHTF2,AAAS" Drug 3718_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,ADRA1D,NME5,LTBP4,CDK10,PPP4R4,DNAH17,NRP2,CFAP410,HAP1,CNTFR,CNTNAP2,ERC2,SPOCK2,ECM2,LRRC17,ARMCX1,NSG1,GSTM5,SOX21,IRF8,KCNB1,KIFC3,MMP16,PDE4B,PFKFB2,NLE1,PURG,LRRN3,NKAIN1,FAM184A,PNMA8A,SPTB,CHST5,FLRT2,ZBTB14" Drug 2408_DN Disopyramide [3737-09-5]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ALK,ANK2,MAP4K3,APC,CDK10,RIPK1,SCAPER,CAMK2G,CAST,SOCS6,KIAA0753,DPH1,FEM1B,COQ7,F5,ZNF589,SRCAP,ZNF276,SPACA9,MAP4,PFKFB2,ZSCAN32,ZNF493,RET,TCP11L1,STUM,DDN,TROVE2,EXOC7,IQCE,TK2,PIK3R5,TPM2,UBTF,XRCC4,GDPD5" Drug 4362_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "KDM5D,AGT,AMPH,APOC1,BAIAP3,ARHGEF2,CRMP1,VCAN,CNTNAP2,RIPOR2,SPOCK2,BRINP1,JAKMIP2,ECM2,EDNRA,EPHB1,NRN1,EFCAB2,FYN,GNAO1,ADAMTS13,GRM8,KCNN1,TAGLN3,MYT1,OGG1,LRRN3,RORB,KCNIP1,SLC8A1,ZNF415,IZUMO4,CDK19,SLC19A3,KCNAB1,GJC2" Drug 7471_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADCY6,CDC42BPA,CDC14B,CASK,MPDZ,SYNJ2,ARHGEF7,CBFA2T2,SOCS6,PPP6R2,DCAF8,HDAC4,DENND4A,IP6K2,HSF2,MBP,SCAMP5,NEK1,NF1,NFYA,NPR2,SLC11A2,CCSER2,PPP3CC,CNNM2,FAM184A,RNASEL,FUZ,EPN2,ZBTB43,ARHGEF9,COBL,TRIM2,METTL3,UBTF,KAT6A" Drug 1935_DN Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG3,APBB2,SYNJ2,CDH2,PPP6R2,SPOCK2,KCTD3,FGFR1,CAMKK2,ATP2C1,STAU2,MPP6,TRAF3IP2,CRCP,GRIK5,GUCY1B1,HAS2,MAP4,MEF2C,MX1,NFYA,CNNM2,RAP1GDS1,RBBP6,ABLIM3,SLC11A1,ELMO2,SMARCC2,NMNAT2,ZBTB43,CEP68,DMXL2,TRIM2,TRPM2,KLC2,ZNF32" Drug 3304_DN Calciferol [50-14-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABR,ADORA2A,APOC1,CAMK2G,ARHGEF2,SOCS6,TAOK2,VAX2,CTH,TBC1D5,MAML1,GIT2,MFAP3L,RCAN1,EFCAB2,FAM49B,RAB30,FERMT2,TDRKH,LIG4,SCAMP5,MPP2,NF1,NFYA,PRKAR1B,RPS6KA2,ANKRD6,FAM214B,KDM4B,EXOC7,FBXW11,KAT6B,PLPPR2,ZNF45,REEP1,GDPD5" Drug 4277_UP Heliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC14B,CDK10,ZSCAN18,BMPR1B,MTMR3,P2RX6,CD86,CNTFR,COL9A3,CSF1R,HEPH,ECM2,ELN,ZNF549,DLC1,ZMYND10,FOLR2,SIGLEC8,GRM2,KCNB1,KHK,MAP2,MMP16,NF1,NTRK2,ABCB1,VPS13C,MARCH1,RASGRF1,RFX2,RGS12,KLHDC8A,ATP10B,TIAM1,UBE3A,EPM2A" Drug 6822_DN Riboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AK2,EPB41L5,ATP6V0A1,BCL7A,GYG2,CAMK2B,FOXN3,TAOK2,RAB28,SH2B1,MFAP3L,DNM1,ING4,DENND4A,FHL1,CINP,DISC1,GLYR1,GSN,ATXN2L,DHX35,KCNH2,LSS,KITLG,NF1,NFYA,STRN3,FAM192A,BTBD7,SNCA,SOX3,ASTN2,PARD3,ZBTB14,EVI5,SMIM8" Drug 1374_UP Nicergoline; Up 200; 8.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA2A,APBA2,APOC1,RIPK1,CBFA2T2,SRSF11,SEC31B,CRY2,PPP1R16B,GIT2,PARD6A,FEM1B,MRNIP,RASGRP2,RABEPK,VPS26C,F8,SRCAP,GFER,IL6R,KIF2A,MBD1,ENPP2,PLEC,SLC25A23,PTPRN2,PTX3,MSANTD2,ATXN7,KBTBD4,ZSWIM8,DBNDD2,THSD1,EVI5,RNF103,AAAS" Drug 4532_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ACHE,PPFIA4,NCOA1,RGS9,BMP7,BAIAP3,CACNA2D1,HAP1,SEPT7,MYEF2,EDN1,EDN3,EPB41,FGF1,HPCAL4,FYB1,ERAP1,PRUNE2,ADAM22,NELL2,NOVA2,CCSER2,NECAB2,RASGRF1,NEK11,RASA3,FRMPD1,SLC12A4,TROVE2,THRA,UGT8,VIPR2,VLDLR,SLC30A4,MAP3K12,EVI5" Drug 3574_DN Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "PPFIA3,PPP4R4,TAOK2,SULT4A1,AKAP7,CRY2,ABCG1,DCAF8,DBN1,MFAP3L,EIF4G2,MTSS1L,SEMA4D,USP21,INPP5K,HNMT,ICA1,ADAM22,PCDH9,LRP12,MBOAT7,SUSD4,GTDC1,NEK11,TCP11L1,EMID1,SH3BP2,CCDC88A,ZKSCAN3,CAMTA2,NXT2,ARHGEF9,EXOC7,ZEB1,THRA,CDK20" Drug 4506_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,AK2,APOC1,ADGRB2,IL33,LHX2,LY86,AKAP7,HAPLN1,CSF1R,PDE4DIP,SGSM2,EDNRA,TNK2,SCML2,FGF1,SYT17,KCNMB4,MAPT,TM6SF1,MMP16,PPARA,GRAMD1C,PTN,GAL3ST4,CARF,NEK11,PPP4R3A,SLC9A5,UNC5B,DDN,TNS2,LMF1,ZNF24,EPM2A,DPF3" Drug 575_DN copper(II) sulfate pentahydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ARRB2,SLC4A4,CFAP410,SULT4A1,ARHGEF6,CDC42BPB,HINFP,PPP6R2,SPATA2,C2CD2L,KLHL3,E2F5,BAIAP2,SEC23B,SMC2,PDLIM5,BTN2A1,SYNPO,KCNJ5,IPO5,GIT1,MYT1,NOVA1,NPTX1,CDK18,CCSER2,SMIM7,PPM1B,GAL3ST4,KBTBD4,SMARCD3,KDM4B,GLT8D1,TBL1X,ZIC1,MPPE1" Drug 4553_UP U-62066 [87151-85-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ACHE,AMT,EPB41L5,GAS7,CDK13,SLC4A4,NRP2,EPS15L1,CNTNAP2,MFAP3L,DRP2,EDN1,HIPK3,DLC1,AFF2,FYB1,ZNF44,SIGLEC8,ALDH1L1,SRCAP,ADAM28,ICA1,IL6ST,LIG4,MMP16,FA2H,POLG,POU6F1,CCDC40,SH3BP2,DZIP1,ZNF415,IZUMO4,SS18,KIAA1107,PCDHGA10" Drug 4819_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1B,SPARCL1,SEMA6A,GAS7,LDLRAD4,KRIT1,QKI,NECTIN3,ARMCX2,KIAA0753,SHANK1,RRAGB,FHL1,ATXN2L,HLF,ICA1,IL6R,IL6ST,JAK2,MAN2A2,MKLN1,CDK18,CEP41,PRKAR1B,MAPK7,GRAMD1C,TCP11L1,ZFP30,CCDC88A,SLC11A1,SMG6,AP4E1,FAM155A,XRCC4,NT5M,PLSCR4" Drug 1322_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABHD6,BIN1,NCOA1,ATP2A2,C5,MYRF,KYAT1,LARGE1,TAOK2,RAB33A,ARHGEF10,PPP6R2,ZFYVE16,FCF1,RASGRP2,NCALD,KAT8,ZNF589,SEPT9,ALDH1L1,COPS8,ELOVL5,NLE1,PMP22,PTCH1,RIPOR1,FUZ,BTBD7,DOK5,SPTAN1,STX1A,ADGRL3,TNS1,HIRA,ZNF32,UBE3B" Drug 1790_UP Folic acid [59-30-3]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "SHROOM2,N4BP2L1,CA12,HIP1R,CLDN10,KYAT1,FAM189A2,TMEM184B,IQCK,PPP6R2,DCTN1,MBNL2,EGR3,RASGRP2,TRMO,POMT1,ALDH1L1,ACOT7,KIF5A,NFYA,PLCB2,CNNM2,DEF8,RGS12,ZNF671,SLC11A1,ELMO2,KDM4B,FAM208A,TCF4,GORASP1,VIPR2,CLIP2,TRIM9,URM1,SLC17A7" Drug 1531_UP Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA1,C1QTNF3,SRPX,ALK,AMT,MARK4,CA4,ARHGEF2,CACNA2D2,TAOK2,CRMP1,DCAF4,MFAP3L,PARD6A,PLXNC1,PIPOX,AGAP2,TRAF3IP2,SRCAP,GFER,MSL3,TDRKH,TJAP1,IL6ST,JAK2,KCNN1,ADAM22,ZNF862,PPP5C,CNKSR2,SLC11A1,SYN2,SYNE1,PDIA2,WIPF1,EPM2A" Drug 2215_DN Disulfiram [97-77-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,PLA2G4C,BCL7A,CCNT1,CLGN,CRLF1,FOXN3,NECTIN3,MFAP3L,SLC12A6,EGFR,EIF4G2,FHL1,GCNT2,GNG4,TDRKH,STON1,GPER1,GPR37,GRIK5,ATXN2L,HNMT,MAP4,CDK18,GSTCD,MAP6D1,EPN2,SPART,ST5,PHLDB1,RPGRIP1L,CRTC1,CHST8,THRA,FAM155A,KCNAB1" Drug 1932_UP Metolazone [17560-51-9]; Up 200; 11uM; PC3; HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,CDC42BPA,APLP1,ZBTB10,NCOA1,HIP1R,CDH2,CST3,SNPH,GIT2,DDX46,ERBB2,ERCC2,FGF1,BAIAP2,DLL3,DENND2A,DISC1,GFER,GLYR1,PRRC2B,GPER1,PTOV1,NME4,PALM,RGS3,SEC14L1,CDK5RAP2,WSCD1,KIAA0930,CABIN1,PLPPR2,NPDC1,FTSJ1,ITM2C,PCBP4" Drug 2289_DN Cloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,ADORA1,PPP4R4,CFLAR,SGCE,MAGI1,PLEKHB1,CNOT8,CNTN1,WHRN,GREB1,PLXNC1,ANKFY1,PDLIM5,ALDH1L1,SRCAP,CNTRL,IL6ST,KHK,ADAM22,ZNF862,NF1,NPR2,PDPK1,MAPK7,KCTD17,GSTCD,TSNAXIP1,ARHGEF9,EXOC7,PCDHA6,PCDHA5,SLC44A1,LAT2,PHTF2,JPH3" Drug 7268_UP Isoxicam [34552-84-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,ARRB2,ZBTB10,PTBP2,EPS15L1,EIF5,TUBD1,ANKMY1,ST3GAL6,TPK1,COPS8,TDRKH,GPER1,MUM1,MAN1B1,KCNN1,MKLN1,AFDN,NACA,NF1,PIK3R1,STRN3,MAPK7,PTPRN2,AP1AR,ZHX3,SPTAN1,ZBTB43,THSD1,SS18,ELOVL4,ASTN2,KIAA1107,ZNF189,NAV3,PLSCR4" Drug 6515_UP Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA2A,AK2,CACNA2D1,CAMK2A,SCARB1,TAOK2,QKI,AKAP7,PCYT1B,SH2B1,VCAN,GREB1,ARHGEF4,SPOCK2,AASS,FGF13,FHL1,PRELID3A,OGA,SEPT9,GPD2,GPER1,GSTM5,MMP16,MSI1,ADAM22,MX1,CNOT4,PLCD1,TCP11L1,ST6GAL1,EXOC7,XRCC4,ADAMTS9,KCNAB1,PLSCR4" Drug 6575_UP Gly-His-Lys acetate salt; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "MAP4K3,CASK,NCOA1,MTMR2,CAMK2G,CLGN,SOCS6,LHX2,CLCN3,RNF14,SOCS5,APPL1,PPP6R2,TOM1,STX2,EFCAB2,OGA,ERAP1,INPP5K,POLL,BTN2A1,ATXN2L,MEIS2,LYRM9,NEK1,NPR2,SIRT2,BTBD7,MAPKBP1,KDM4C,IQCE,TMPO,REEP1,EPM2A,FZD3,RNF146" Drug 1185_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "RALGAPA1,ASIC1,TRMT9B,GAS7,SLC16A4,TPP1,IQCK,HINFP,CSF1,PDE4DIP,SLITRK5,RIMS2,KIAA0753,DTNA,EGR3,MRNIP,EIF1,EPB41L2,NRN1,ERAP1,INPP5K,ALDH1L1,GLYR1,NEFH,NINJ2,PIK3R1,TMEM231,KLHDC8A,TRAPPC13,SH3BP2,SPTAN1,RBM26,SS18,PDLIM2,TNS1,PHTF2" Drug 5697_UP Chlormezanone [80-77-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,ADORA1,AP2A2,ADGRF5,BIN1,OGT,CDC14B,AZGP1,SCAPER,CABP1,NECTIN3,AATK,ARHGEF4,EGFR,TENM1,ETV1,RASL10A,SRCAP,LPAR4,GUCY1A1,SHISAL1,TJAP1,MT1M,MYCN,NF1,PCDHGC3,RFX2,ST8SIA1,PKNOX2,FAIM2,PHLDB1,TCF4,TPM2,VLDLR,WIPF1,HRASLS" Drug 2866_UP Budesonide [51333-22-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA1,ADRA1B,CDC42BPA,CDK13,STX16,NRP2,CACNA1G,CA4,IPCEF1,CNTNAP2,ARHGEF4,CDON,SHANK1,DTNB,EGFR,ANKMY1,DLC1,PRELID3A,SIGLEC8,GNAL,PCLO,GRIK5,MSR1,TMOD2,MTRF1L,ZNF493,S100B,SALL1,STUM,ASAP3,SLC14A1,NMNAT2,ZBTB43,POGZ,ARC,KCNAB1" Drug 6790_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "RALGAPA1,C1QTNF3,APOC1,ADAM23,ADGRB3,CBFA2T2,SRSF11,JAKMIP2,RUSC2,TMCC2,HSD17B14,F5,ZNF589,FYB1,ALDH1L1,GFER,GNAL,LPAR4,CNTRL,CACFD1,HNMT,JAK2,KCNJ5,ADAM22,NF1,PDE4A,MAPK7,SLC14A1,VPS13A,TAL1,SMG6,THRA,CABIN1,LAT2,HPS4,ST7" Drug 7211_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "EPB41L5,CDK13,CFLAR,C5,SCARB1,QKI,PDE4DIP,RUBCN,DCAF8,DBT,DCTN1,C2CD2L,FEM1B,STX2,POLR1B,INPP5K,MSL3,INPP5B,IPO5,NCAM2,OPA1,PDE4A,RIPOR1,RIC8B,ERC1,ZBTB43,CLASP2,ELOVL4,STXBP1,NSFL1C,ARHGEF9,ASTN2,EXOC7,IQCE,DOCK9,METTL3" Drug 2050_UP Tamoxifen citrate [54965-24-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1D,C1QTNF1,OGT,BMP7,FUBP1,MYRF,SYNGR3,HOMER3,CREM,VCAN,HDAC9,DBT,PLXNC1,CDKL3,B4GALNT1,SRCAP,GLI2,GLYR1,LPAR4,SHISAL1,KCNJ5,GPR85,FA2H,POLG,PTCH1,SH3TC2,RGS4,SUGCT,MAPK12,SUPT20H,SNCA,TSNAXIP1,DDN,IQCE,ZNF34,CBX5" Drug 7363_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,CDC42BPA,NRP2,PICK1,NRG2,CSF1,PLXNC1,OGA,SIGLEC8,CSDC2,GLI2,IRAK3,SHISAL1,IL12A,MMP16,NOVA1,PDE4D,PRKAR1B,TCP11L1,EMID1,SH3BP2,FUZ,NLGN1,KANSL3,BTBD7,RBM34,ZSWIM8,HECW1,PHLDB1,TCF4,CRTC1,SLC44A1,CABIN1,AMACR,KCNK12,KCNAB1" Drug 3606_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA1,SPARCL1,SYT13,APOC1,MARK4,LDLRAD4,CPS1,PYGO1,KLHL3,GSDME,EDN1,FRY,EGR3,DLC1,FOLR2,SHISAL1,KIF5A,KIT,MAPT,MN1,MYCN,MYO7A,NELL2,NF1,NNAT,TREM2,PALM,SEPT4,ELOVL2,PEG10,ARC,SYN2,ADGRL3,SZT2,TPM2,SEMA3B" Drug 5839_UP Kaempferol [520-18-3]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,ACTN1,BIN1,AMT,PKP4,ARNTL,ALDH7A1,KIF1A,ST3GAL5,ARHGAP33,ASIC3,QKI,VCAN,PDE4DIP,MFAP3L,HS3ST2,FCF1,SCML2,GALC,ERAP1,GPD2,SPACA9,JAK2,ADAM22,TAGLN3,STRN3,FAM184A,CSRNP3,ASAP3,FNDC3A,NMNAT2,SS18,MCF2L,TRIM2,ZKSCAN5,TFIP11" Drug 2065_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "C1QTNF1,ADAM15,SYNJ2,MYRF,BAIAP3,RAB28,USP6NL,DBT,SPATA2,MFAP3L,DPH1,DTNB,TOM1,HIPK3,ZNF589,FGF1,TMEM8B,SRCAP,SYNPO,ICA1,LIG4,GIT1,PPP5C,PRKAR1B,WDR25,PID1,SH3TC2,AMBRA1,ELMO2,KDM4C,UNC5B,DBNDD2,EXOC7,SSBP2,ZNF24,HPS4" Drug 6020_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "C1QTNF3,LTBP4,BIN1,APC,PPFIA3,CFAP410,CA4,CAMK2G,KYAT1,EPS15L1,CRY2,PDE4DIP,MAML1,TMCC2,ENO2,RASGRP2,PRELID3A,INPP5K,SRCAP,GSTM5,NXPH3,ICA1,KPNA5,MEF2C,CDK18,PGAM2,GRAMD1C,PRPH,EMID1,SH3BP2,KDM4C,SPTB,CDK19,TACC1,UBE3A,SLC17A7" Drug 1472_UP Levodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC42BPA,APC,GAS7,ARHGDIG,SCAPER,HAP1,CAMK2G,ASIC3,WHRN,CST3,GREB1,RUSC2,FYN,INPP5K,ALDH1L1,GLYR1,GRIK5,CACFD1,INPP5B,MMP16,RETREG1,PPARA,FAM184A,EMID1,FBXO11,PPP4R3A,SMARCD3,FNBP1,KDM4C,ARC,IQCE,SIN3B,TRIM2,WBP2,KCNK12,MPPE1" Drug 4201_UP Atovaquone [95233-18-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,PKP4,CDK10,N4BP2L1,SCAPER,HAP1,SYNGR3,MAGI1,FOXN3,CHN2,DTNA,ECM2,SPEG,HPCAL4,ERGIC3,ERAP1,DISC1,PCDH17,RAB30,GNAO1,CACFD1,HNMT,LSS,NF1,NPTX1,PNMA3,TRAPPC13,ZFP30,DZIP1,ZNF334,SNAP25,KIF13A,TBCEL,PCDHA5,WIPF1,KCNK12" Drug 5494_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,C1QTNF3,AMPD2,PPFIA3,C5,TBRG4,RAB28,CREM,LRIG1,KIAA0586,DBT,EPB41L2,STX2,FGF12,FHL1,SEMA4D,B4GALNT1,ERAP1,SRCAP,POLL,TDRKH,CLASRP,MAP4,MEIS1,NME4,NTRK2,OGG1,PPP5C,NKAIN1,RPS20,ZBTB43,TSPYL2,NXT2,ZNF34,VGF,URM1" Drug 6265_DN Thioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,EP400,STX16,CCNT1,CBFA2T2,SCARB1,LHX2,ABCG1,GIT2,PARD6A,CDKL3,FGFR1,NOP56,INPP5K,MSL3,GNG4,IPO5,MITF,NACA,NCAM2,NF1,NFYA,OPA1,NEK11,AMBRA1,PEX26,EPN2,MAPKBP1,UHRF1BP1L,SS18,OBSL1,KAT6B,VGF,KLC2,ZNF24,ZBTB38" Drug 6476_DN Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AMPD3,BIN1,ADAM15,BAIAP3,CA12,RAB28,ARMCX2,ING4,EPB41L2,FGFR1,SEMA4D,OGA,FYB1,TXNL4A,MSL3,STON1,GPER1,CNTRL,KCNH2,IPO5,LMO2,ZNF862,NELL2,NFYA,NPTX1,WDR25,RGS3,RNASEL,SLC6A8,LIMCH1,THSD1,SMG6,THRA,TPM1,CDK20,URM1" Drug 3406_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "RALGAPA1,AMPD3,APOC1,PPFIA3,SLC2A11,KIF1A,CACNA2D2,TPP1,GREB1,RCAN1,EDNRA,EGR3,HSD17B14,SCML2,TMEM164,FHL1,TXNL4A,ATXN2L,KCNF1,SHC3,MGAT3,PCBP3,SAMD9,ZSCAN32,ZDHHC14,RGS3,SGK1,SYBU,SNCA,KDM4B,STX1A,EXOC7,VGF,REEP1,UBE3B,PHTF2" Drug 7254_DN Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "MPDZ,LHX2,WHRN,CSNK1E,GPRASP1,SUGP2,PLEKHA1,ING4,USPL1,SPEG,EZH1,ANKFY1,EFCAB2,INPP5K,SRCAP,GRB10,SLC2A6,KIRREL1,AMBRA1,SLC6A8,CCDC88A,KBTBD4,ELMO2,SMARCC2,PDZD2,EXOC7,DNMBP,FBXW11,TNS2,TK2,TNS1,MAP3K12,VPS35L,MPPE1,PDSS2,TIGD6" Drug 2473_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADCY6,AGT,FAM135A,AMH,CFAP410,CBFA2T2,CACNA2D2,CHN1,RAB26,AKAP6,CREM,CRMP1,SV2B,RRAGB,B4GALNT1,SIGLEC8,GDF9,HLF,KCNJ5,KCNN1,KIF5A,MAP4,MEF2C,MMP17,P2RY13,NTRK2,PURG,BCAS3,PTPN13,CNKSR2,SEPT8,CDK20,RUNDC3B,LMF1,CLIP2,NLRP3" Drug 2989_DN Benzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,AGT,ADAM15,CACNB4,SLC16A4,CBFA2T2,NRG2,SLITRK5,ZNF337,BRINP1,TOM1,E2F5,RASGRP2,DLC1,EFCAB2,ADAM28,PRUNE2,LILRA2,MAPT,PTN,PTPRB,TCP11L1,FRMPD1,ANKRD6,EPN2,MYH15,SYT5,KIAA1107,DMXL2,SZT2,DOCK9,CDK20,TRO,LMF1,SEMA3B,PCBP4" Drug 6407_UP 3-nitropropionic acid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,PPP4R4,ARHGEF1,RCBTB2,CNOT8,LHX2,CSF1,PDE4DIP,EDIL3,MRNIP,RGS17,APC2,FGFR1,FYN,INPP5K,MSL3,GNG4,GRIK5,MMP16,NPR2,PRKAR1B,PRPH,CNTLN,ZSCAN32,TCP11L1,RXRA,STUM,FUZ,SNCA,KDM4B,ZHX3,COBL,TBCEL,CHST5,VGF,ZNF74" Drug 6105_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA2A,ALK,ANK2,ALDH7A1,RGS9,THSD7A,CDH2,HAPLN1,DGKG,BRINP1,CDON,IGSF6,EFCAB2,NSG1,SRCAP,LPAR4,GSTM5,ATXN2L,KCNH2,ZNF862,NF1,NOVA1,NTRK2,PPP5C,ZMAT4,KCTD17,KLHDC8A,TCP11L1,SLC11A1,ARC,DOCK9,PHF24,PLPPR2,WIPF1,HRASLS,JPH3" Drug 7255_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,PPFIA3,MADD,MPDZ,CFLAR,CA12,CLCN3,ARHGAP32,ZFYVE16,EIF5,ETV1,FGFR1,IP6K2,ANKFY1,EFCAB2,SESN1,RASSF8,MMP16,SETD4,PCDH9,CCSER2,SLC25A23,PTPN13,TMEM231,PID1,BTBD7,TTC17,ZNF415,EXOC7,AGTPBP1,TRIM2,CABIN1,TSC1,SSBP2,FAM155A,ITM2C" Drug 3615_UP Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "SYN3,AK2,SYT13,AMPH,BIN1,CAMK2B,CAST,NRXN3,CNN3,CPS1,CSF1,ELMO1,TMCC2,EXOG,ERCC2,DCTN2,FAM49B,CSPG5,DENND2A,HPGDS,GNAO1,SYNPO,INPP5B,KCNH2,KIFC3,LSS,NTRK3,PTCH1,PTH1R,ELOVL2,ZFP2,STUM,SLC11A1,ZSWIM8,CUX2,UBE3A" Drug 1263_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NCOA1,SCAPER,C5,LDLRAD4,HOMER3,KIAA0586,MAML1,DBN1,B3GAT3,DTNA,TOM1,FGFR1,NOP56,FYB1,DISC1,SEPT9,CRCP,CACFD1,SLC2A6,MIA2,POLG,PPP3CC,CEP97,FAM184A,MAPK12,SH3BP2,FUZ,COA1,SMARCC2,MAPKBP1,CABIN1,TNS1,TRPS1,SSBP2,HIRA,NPDC1" Drug 3741_DN Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABR,ADGRF5,C1QTNF3,TRMT9B,PPFIA3,ADAM15,ADGRB2,ST3GAL5,CAMK2B,LARGE1,CSNK1E,CNTNAP2,MAML1,PARD6A,DTNA,FGFR1,PDLIM5,TRAF3IP2,CACFD1,MAPT,NELL2,PDE4A,PDE4B,PFKFB2,RETREG1,CEP41,C1orf54,ZCWPW1,MRAS,PPP4R3A,TSNAXIP1,SPTB,SZT2,VGF,VIPR2,TIGD6" Drug 1488_UP Captopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BIN1,CDC42BPA,APAF1,APBB2,SLC4A4,CFLAR,SCAPER,GYG2,ARHGAP33,GREB1,LYPD1,SHANK1,PHF20L1,SPEG,FGFR1,BAIAP2,ELOVL5,C2orf72,INPP5B,KCNH2,KCNN1,ADAM22,NF1,CLDN11,PDE4D,PRKAR1B,BTBD7,MAPKBP1,SNCA,ARHGAP26,ARC,MCF2L,EXOC7,CRTC1,KCNK12,SPHK2" Drug 892_UP 5162773; Up 200; 7uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADD1,APBB2,SLC4A4,STX16,CFLAR,CAMK2B,CBFA2T2,LRRFIP1,FAM189A2,VAX2,ARHGEF4,GIT2,DTNA,FCF1,RRAGB,REEP2,RAB30,GPD2,SPACA9,GRM8,HNMT,KIF2A,MPP2,LYRM9,CNOT4,PRKAB2,ZNF821,FNDC3A,ANKRD6,FAM214B,PHLDB1,ARHGEF9,MTCL1,KAT6B,XRCC4,SENP7" Drug 2921_DN Cefalonium [5575-21-3]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BRAP,OSBPL1A,CAMK2G,KRIT1,ARHGEF1,SOCS6,TPP1,CLOCK,PPP1R16B,EXOG,DTNA,TSPAN5,ZNF589,ATP2C1,COPS8,RAB40B,MAP4,MX1,CNOT4,MINDY2,SNRK,ZCWPW1,ZNF671,TCP11L1,CLIP1,RXRA,TRAPPC13,PEX26,ZHX3,STX1A,KLHL7,TNS1,TPM1,MAP3K12,GDPD5,UBE3B" Drug 3616_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,AP2A2,AMT,ARHGDIG,SGCE,CA4,ARHGAP33,FOXN3,SOCS6,STOML1,BAG4,SIPA1L1,PDE4DIP,MFAP3L,EXOG,DMPK,MRNIP,GAD1,B4GALNT1,ALDH1L1,MSL3,ITPKB,LYRM9,PPP5C,PRKCB,PRPH,PTPRO,ZSCAN2,ZHX3,KDM4C,STX1A,SLC44A1,FLRT2,PLSCR4,EPM2A,ST7" Drug 3289_DN Biotin [58-85-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,APOC1,NCOA1,STX16,SYNJ2,CFAP410,LRRFIP1,CLGN,PLEKHB1,SH2B1,CSNK1E,DCAF8,CNNM1,TXNL4A,SLC2A6,PADI2,HNMT,IL6ST,KCNH2,MAP4,MBD1,MPP2,POLG,RIPOR1,SLC25A36,GSTCD,ROBO1,TRA2B,TROVE2,SS18,ASTN2,TACC1,IQCE,TBL1X,GDPD5,HPS4" Drug 2256_UP Etofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADGRB2,CACNA1I,BAIAP3,RUNX1T1,CHN2,STOML1,RIMS2,PPP6R2,TBC1D5,DGKG,SPOCK2,DTNB,ZNF589,FGFR1,NSG1,ERAP1,ADAM28,GNAO1,HLF,SHISAL1,MAP4,MBD1,NNAT,PDE4D,TRHDE,RPS6KA2,ASAP3,FNDC3A,SLC2A5,SNAP25,FAIM2,ZHX3,TACR1,TLR4,ZNF45,AP3B2" Drug 1203_DN haloperidol; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,MTUS1,CDC42BPA,MARCH3,BCHE,WASF1,CA12,ARMC8,SNPH,LYPD1,SPEG,EZH1,SCML2,FGF1,POMT1,CGREF1,AHDC1,MAP4,SCAMP5,SETD4,LRP12,PPP5C,ASAP3,CCDC88A,SNCA,ZBTB43,SPART,ELOVL4,STX1A,TK2,CLIP2,TRIM9,NDRG4,EPM2A,FZD3,ST7" Drug 3061_UP Felbinac [5728-52-9]; Up 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ACHE,ADCY8,TRMT9B,CDC42BPA,ANK2,MPDZ,CACNA1G,BAIAP3,CACNB4,KALRN,RUNX1T1,USP2,ENTPD2,DLGAP1,NRG2,CRYBB1,PDE4DIP,BRINP1,EDN1,SRPK3,VPS13B,AGAP2,SIGLEC8,GPR75,GNAL,GPR37,HNMT,ADAM11,DUSP26,RASGRF1,ASAP3,DBNDD2,ARC,AP4E1,TK2,LMF1" Drug 1889_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "PPFIA3,MARK4,ATP6V0A1,ARHGEF7,ARHGEF2,FOXN3,CSNK1E,CST3,ARHGAP32,TM9SF4,GIT2,RUSC2,C2CD2L,KLHL3,TNK2,TMEM8B,DISC1,HTATSF1,CACFD1,MX1,CLDN11,PALM,RETREG1,PCMTD2,ZNF821,TRA2B,SH3BP2,ST6GAL1,ARHGEF40,STXBP1,IQCE,WSCD1,TRIM2,NACC2,CBX5,WNT7A" Drug 223_DN TTNPB; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ALK,CDC42BPA,APBA2,MYRF,P2RX6,LHX2,CLIP3,AATK,GREB1,KLHL3,EIF4G2,MRNIP,SCARA3,TRMO,FYB1,GNAL,NXPH3,KHK,LAMA2,MYO7A,MYT1,PCDH9,MAPK3,BEND5,TCP11L1,EMID1,FERMT1,KDM4B,TROVE2,PRRC2C,COBL,PARD3,TNS1,PLPPR2,ZNF32,MPPE1" Drug 5504_UP Lisinopril [83915-83-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "SYN3,FZD9,AMT,APBA2,GAS7,DDO,SCAPER,DCLK1,CLGN,CSF1R,PIPOX,CORO2B,ZNF589,FHL1,FYN,GRB10,SHISAL1,ZNF862,NFYA,NTRK2,OPRL1,PLCD1,MTRF1L,LRP12,ZDHHC14,SBF1,ASAP3,SYBU,ARHGEF40,SMARCD3,ZSWIM8,IZUMO4,KDM4C,ZC3H13,WSCD1,CABIN1" Drug 2071_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADGRF5,APBB2,ADAM15,MYRF,LDLRAD4,ARHGEF1,TBRG4,PLEKHB1,AKAP7,COL9A3,AKAP5,BAG4,CRY2,DAPK3,GIT2,IRAK4,TUBD1,VPS26C,ZNF589,STON1,KIFC3,PDE4B,PLEC,PTPRH,RIPOR1,FAM184A,FBXW7,SLC6A8,SLC22A4,ZNF415,SS18,SZT2,ZNF34,SSBP2,SPHK2,UBE3B" Drug 3985_UP Troleandomycin [2751-09-9]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ATP2B2,CALB2,ARHGAP33,NRXN3,LY86,CNTFR,AKAP5,DPP6,EDIL3,HIPK3,CELSR3,ADAM28,CSDC2,SPACA9,C2orf72,IL12A,KCNF1,MMP16,CNOT4,NTRK3,PLCD1,CEP41,WDR25,RGS4,MRAS,KANSL3,ZNF334,DOK5,ARHGAP26,PHLDB1,ARC,TBCEL,SLC44A1,HIRA,VIPR2,NLRP3" Drug 4735_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,APC,APOC1,CDK13,CFLAR,SCAPER,ARHGAP24,EDNRB,EGFR,C3orf18,SPEG,PTK2B,FGF13,FGFR1,PDLIM5,PRELID3A,DISC1,PCDH17,ATXN2L,KCNH2,KCNN1,KCNQ3,MATN3,AFDN,ADAM22,P2RY13,NF1,NPR2,MINDY2,MAPK7,FAM214B,FAIM2,TSPYL2,SLC19A3,WIPF1,LAT2" Drug 5414_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,ALK,APBA2,APBB2,MARK4,AZGP1,CFLAR,MTMR3,CACNA1I,LDLRAD4,CBFA2T2,EPS15L1,SULT4A1,GREB1,DTNA,EDNRA,COQ7,F5,CORO2B,DLC1,ALDH1L1,GLYR1,PCLO,RASSF8,ATXN2L,KCNN1,LMO2,NEFM,RETREG2,PPP5C,PTN,SATB1,LIMCH1,KIAA1107,UCHL1,MKRN3" Drug 5057_DN Torsemide [56211-40-6]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "EPB41L5,CDC14B,ARNTL,NUMB,SYNJ1,SYNJ2,CBFA2T2,PLEKHB1,IQCK,ARMC8,ENTPD4,CSF1R,CSNK1E,SNPH,DPH1,ING4,CGREF1,TRAF3IP2,DENND2A,GPR37,BACH2,NLE1,RXRA,DZIP1,PEX26,LIMS2,ARFGAP1,TMCC1,KIAA0930,GPR161,TK2,OSBP2,WIPF1,ZNF24,EVI5,KCNAB1" Drug 4568_DN Sparteine (-) [90-39-1]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1D,C1QTNF1,KCNAB2,SYNJ2,MYRF,QKI,SLC4A8,HAPLN1,ARHGEF10,SNPH,EXOG,MRNIP,ERCC2,BAIAP2,FYB1,FYN,SYNPO,INPP5B,JAK2,LSS,MT1M,PFKFB2,STRN3,PID1,COA1,MYH15,KDM4B,KIAA1107,IQCE,VIPR2,LAT2,XRCC4,MAP3K12,NT5M,PCBP4,PHTF2" Drug 5526_UP Prednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "BEGAIN,CDC42BPA,ATP6V0A1,NRP2,CAMK2A,SIPA1L1,VCAN,MAML1,HEPH,GSDME,DTNA,TNK2,FHL1,HPCAL4,AFF2,GAD1,RUNDC3A,PRUNE2,ATXN2L,ICA1,IGF1,PPP5C,MAPK10,SYBU,ZSWIM8,PEG10,STX1A,SYT5,WSCD1,DOCK9,FAM189A1,TNS2,TK2,TNS1,KCNK12,SLC30A3" Drug 7454_DN Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC42BPA,APAF1,PPFIA3,ST3GAL5,CAMK2G,C2CD2L,EXOG,SUGP2,TNK2,CD320,BAIAP2,GPD2,HSF2,IDH3B,SCAMP5,NPR2,CCSER2,RETREG1,PPP3CC,PRODH,PTPRE,MCMBP,FAM192A,AMBRA1,ZKSCAN3,MAPKBP1,KDM4C,ZBTB43,LHPP,ARHGEF9,TACC1,PLPPR2,VAV1,VGF,REEP1,GDPD5" Drug 2713_DN Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AMT,PPP4R4,CASK,ATP2A2,ARHGEF1,SOCS6,AKAP7,NRG2,PDE4DIP,ZNF337,TUBD1,NCALD,CDKL3,PCYOX1,KHDRBS3,ZNF276,MAN1B1,LSS,MAP4,NNAT,PIK3R1,CCSER2,POU6F1,C1orf109,KDM4B,DOP1A,SIN3B,SZT2,OBSL1,TK2,LMF1,CLIP2,REEP1,EVI5,HPS4,TIGD6" Drug 2251_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC42BPA,AQP6,MARK4,SLC2A11,ADGRB3,NRP2,KSR1,GYG2,CDH2,TAOK2,CSF1R,DMPK,EDN3,PIPOX,ST3GAL6,DCTN2,CSDC2,LYVE1,TJAP1,MEF2C,PDE4A,LRP12,LRRN3,MAPK7,RELN,SAMD9,PTX3,CCDC40,SLC2A5,BTBD7,OGDHL,JMJD6,WSCD1,NT5M,SLC17A7,SMIM8" Drug 4836_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADCY6,NME5,EPB41L5,CDK13,CFLAR,BAIAP3,HAP1,QKI,SULT4A1,CNTFR,CSF1R,CNTNAP2,GREB1,EDN1,ETV1,FGFR1,FHL1,TJAP1,ITGA7,MAN2A2,MSR1,SERPINI1,GRAMD1C,ZFP30,CCDC88A,KDM4B,HECW1,EXOC7,KIAA1107,PCDHA5,TPM1,LAT2,XRCC4,NT5M,GDPD5,SLC17A7" Drug 6355_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "MTUS1,BIN1,KIF1A,ST3GAL5,CACNA1G,KRIT1,FOXN3,B4GALT6,CLCN3,NCOR2,DTNA,MTSS1L,FGFR1,FLT1,DENND2A,GAD1,SYT17,CNTRL,SHISAL1,SCIN,MIA2,ADAM22,NLE1,PPARA,PTCH1,PTPRH,GAL3ST4,TCP11L1,FBXO11,CDK19,TBCEL,TIAM1,WIPF1,XRCC4,ST7,DPF3" Drug 4568_UP Sparteine (-) [90-39-1]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASPHD1,APC,ATP2B2,ADAM23,CACNA1I,CAMK2B,CD86,CHN2,TAOK2,CREM,CNTNAP2,EDNRB,ING4,ZNF391,ETV1,ST3GAL6,PDLIM5,GSN,SOX21,ICA1,LMO2,TM6SF1,NPR2,P2RY1,CCDC40,FRMPD1,FUZ,HECW1,UNC5B,TROVE2,SLC44A1,RIMBP2,UBE3A,REEP1,NAV3,KCNAB1" Drug 165_UP exemestane; Up 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "KCNAB2,APBB2,PRX,N4BP2L1,MPDZ,ST3GAL5,RAB29,KALRN,FOXN3,SLIT2,CNTFR,CNTN1,CRMP1,ACOT8,SUGP2,MBNL2,ETV1,FGFR1,AFF2,PDLIM5,SRCAP,CRCP,SPACA9,PRDM5,NXPH3,SLC11A2,PALM,PTPRD,SEMA6D,SLC12A2,SNAP25,TMCC1,ATP10B,NSFL1C,TP53BP2,CA14" Drug 5789_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "PDE8B,MARCH3,ALDH7A1,SCARB1,STOML1,ARMC8,SLC4A8,SLITRK5,PARD6A,TOM1,ERCC2,FYN,GAD1,PCDH17,TDRKH,ICA1,MAPT,NF1,KCTD15,MAPK7,PTPRE,PTPRH,BEND5,CSRNP3,ZFP30,SLC14A1,BTBD7,SS18,MCF2L,TMEM121,THRA,TIAM1,HIRA,VIPR2,WIPF1,EPM2A" Drug 1660_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADAM15,SYNJ2,GYG2,CRY2,HINFP,PDE4DIP,TBC1D5,DMPK,EIF5,CDKL3,BAIAP2,CAMKK2,HSF2,ITPKB,KCNH2,MAP4,NF1,SLC11A2,RETREG1,PLEC,MBOAT7,NEK11,SUPT20H,SH3BP2,PEX26,EPN2,SPTAN1,CDK19,LHPP,PLCB1,TNS2,TMEM121,PLPPR2,LMF1,KLC2,GDPD5" Drug 6012_UP Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1D,LTBP4,CDK13,CA4,CAMK2B,USP2,CACNA2D2,CSNK1E,PDE4DIP,RASSF2,SPOCK2,SLC12A6,DTNA,ING4,SRPK3,VPS13B,COQ7,RASGRP2,MTSS1L,FGFR3,HPCAL4,IQCG,GALC,KCNN2,MID1,PFKFB2,PPP1R1A,PPP2R2B,GRAMD1C,ZDHHC14,KCTD17,RASA3,TACR1,SZT2,NPL,OSBP2" Drug 2343_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,NDRG3,MTUS1,PROM1,CD86,CREM,SH2B1,CRY2,VCAN,ZFYVE16,EIF4G2,MRNIP,F5,ST3GAL6,ZNF589,ANKFY1,CELF1,KCNN1,TM6SF1,MPP2,NFYA,NLE1,C1orf109,RIPOR1,RGS3,PBRM1,MRAS,FERMT1,CCDC88A,ZNF667,ZBTB43,ATP10B,SIN3B,PLPPR2,MAP3K12,UBE3B" Drug 2244_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA1,ADRA1B,AMH,AMPH,ARHGDIG,TAOK2,SULT4A1,AKAP6,DOCK4,SPOCK2,DMPK,DYNC1I1,HEYL,SPEG,ETV1,REEP2,OGA,NEU3,MSL3,SMAD1,OPRL1,PRKCB,MAPK7,SAMD9,RPS6KA2,STUM,ST6GAL1,SLC4A3,SLC9A5,SLC11A1,SP4,SPTB,ATP10B,CLIP2,GDPD5,AP3B2" Drug 5346_DN Calciferol [50-14-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ALCAM,APC,SLC4A4,RAB28,COL4A5,DCAF8,PARD6A,DTNA,TOM1,FECH,FGFR1,FHL1,DISC1,KCNMB4,CNTRL,SLC2A6,IL6ST,JAK2,KIF2A,MAP4,GTDC1,MAPK12,AMBRA1,MAPKBP1,FNBP1,ITPRID2,ARHGEF9,ANKRD12,EXOC7,KAT6B,VAV1,VGF,VIPR2,MAP3K12,HPS4,PCBP4" Drug 3516_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "KIAA1324,TRMT9B,AMH,BIN1,ARHGDIG,ATP2B2,HIP1R,ARHGEF1,CACNA2D2,SIPA1L1,CNTNAP2,RASSF2,TNK2,MTSS1L,CAMKK2,IL6R,MYO7A,MAPK7,CCDC40,FAT4,ZNF493,RASGRF1,KHDRBS2,ZMAT4,RGS12,ST6GAL1,SYBU,PKNOX2,CXXC4,SNCA,ZNF423,CDK19,EXOC7,CUX2,TK2,ZFP37" Drug 5888_DN Mesalamine [89-57-6]; Down 200; 26.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ACTN1,ADD1,AMT,APLP1,PPFIA3,SLC4A4,C5,CNTNAP2,PARD6A,IRAK4,MRNIP,FGFR1,SEMA4D,GAD1,RASSF8,MBD1,MKLN1,MPP2,TAGLN3,PCDH9,PTN,PID1,KHDRBS2,SBF1,SH3BP2,AMBRA1,TMCC1,ZBTB43,VPS13A,IQCE,CBX5,CABIN1,WBP2,PLPPR2,NAV3,MPPE1" Drug 3033_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ACHE,AGT,BIN1,KALRN,RUNX1T1,USP2,NRXN3,CNTN1,COL9A3,ARHGEF10,RIMS2,BRINP1,MFAP3L,TMCC2,EPB41,APC2,CORO2B,TMEM8B,GPD1,GSTM5,HNMT,KCNJ5,KCNN3,MSR1,MYO6,NELL2,NRCAM,OPRL1,MAPK7,DCHS2,CNNM2,PTPN13,SOX15,RIMBP2,MAP3K12,AP3B2" Drug 6511_DN THIP Hydrochloride; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABHD6,C1QTNF3,APC,CDC14B,CDK10,SYNJ2,MTMR2,PLAA,NRG2,CREM,DZIP3,DAPK3,GIT2,CDON,OPTN,EGFR,AHDC1,CNTRL,GRIK5,KCNH2,PPP5C,RIPOR1,EMID1,SBF1,PKNOX2,RBM34,ZC3H13,TSPYL2,THSD1,CEP68,CHST8,VLDLR,CLDND1,PCBP4,MPPE1,ST7" Drug 3520_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG2,ADORA1,NME5,TRMT9B,KCNAB2,APBB2,CACNA2D2,TAOK2,SNPH,HIPK3,ING4,REEP2,FGFR1,SRCAP,RAB30,TJAP1,MAPT,ADAM22,ZNF862,PPP2R2B,LRRN3,PRKCB,RIPOR1,GAL3ST4,KCTD17,ST6GAL1,ABLIM3,SLC2A5,PKNOX2,CXXC4,PDZD2,PCDHGA10,SYNE1,TK2,LAT2,KCNAB1" Drug 4234_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "MTUS1,SEMA6A,DDO,DNAH17,RGS11,SYNJ2,CFAP410,CRLF1,NRXN3,FAM149A,CSF1,PDE4DIP,CNTNAP2,MFAP3L,FGFR3,SIGLEC8,SYT17,GLI2,GRIN2C,SHISAL1,MMP16,ADAM22,NNAT,PURG,GAL3ST4,SEMA6D,SCN2B,ZNF415,PDZRN3,DDN,SPART,MCF2L,SZT2,TRO,VIPR2,KCNK12" Drug 1528_DN Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ABHD6,ALCAM,BACH1,ST3GAL5,KRIT1,CBFA2T2,PLEKHB1,PDE4DIP,DAPK3,FBXL5,DMPK,EGFR,MBNL2,VPS26C,ANKMY1,FER,ANKFY1,GLYR1,BTN2A1,ITPKB,KHK,LSS,RETREG1,PTPRE,RGS3,RNASEL,GALNT10,KIF16B,MAPKBP1,ELOVL4,TNS2,VGF,LMF1,EVI5,PCBP4,ACTR3B" Drug 2316_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "SYN3,ARHGDIG,CFLAR,GYG2,HIP1R,ARHGAP33,CLGN,CHN2,NRG2,CYBB,RASSF2,MAML1,DUSP9,VPS13B,RCAN2,RRAGB,ZNF589,FGF12,FGFR1,POLL,LSS,NF1,PDE1C,LRP12,NECAB2,C1orf54,EMID1,PKNOX2,PEG10,SPTB,THSD1,ZC4H2,ARC,PIK3R5,MPPE1,PHTF2" Drug 5821_DN Tetrandrine [518-34-3]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADRA1D,PDE8B,CFLAR,CA12,CAMK2G,WHRN,CSF1,MED12,ERBB2,ERCC2,CDKL3,FHL1,TRMO,CELF1,TRAF3IP2,PRRC2B,ITPKB,MYO6,PDE1C,PLCD1,LRP12,PTN,SH3TC2,ZDHHC14,SPTAN1,ZBTB43,LHPP,ELOVL4,TTBK2,COBL,WSCD1,TCF4,SATB2,NSD1,LMF1,MAP3K12" Drug 4748_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "LTBP4,APBA2,AZGP1,NRP2,CACNA1G,AATK,RASGRP2,MTSS1L,ZNF391,ETV1,NRN1,FAM198B,EFCAB2,ZNF44,SIGLEC8,TOX3,GPER1,GRIK5,GRIN2C,IL12A,KCNJ5,KHK,SMAD1,AFDN,RGS12,EMID1,SCN8A,SLC2A5,IQSEC2,TAL1,TRPM2,VIPR2,SPHK2,REEP1,SEMA3B,KCNAB1" Drug 2556_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "AP2A2,CDC42BPA,ADAM23,ADAM15,CAST,AP4M1,FOXN3,TPP1,QKI,AKAP7,CREM,PPP1R16B,DOCK4,IRAK4,TUBD1,CINP,FAM49B,INPP5K,CACFD1,NCKAP1L,IPO5,MAP4,MEF2C,AFF1,CNOT4,RETREG1,MSANTD2,PPP4R3A,ARHGEF40,ELMO2,BTBD7,SPTAN1,PDLIM2,DMXL2,THRA,FIP1L1" Drug 5931_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "C1QTNF1,LTBP4,APBB2,MARK4,SLC4A4,ADAM23,ASIC3,ARHGAP22,ABCG2,COL9A3,EDNRA,IRAK4,STX2,SPEG,SCML2,FLT1,CSPG5,B4GALNT1,TMEM8B,STON1,GPER1,HNMT,MAPT,MARK1,KCTD17,GSTCD,ZNF667,CDK19,CEP68,PCDHGA10,TK2,CABIN1,TNS1,KLC2,SMIM8,DPF3" Drug 6672_DN Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "APAF1,STX16,ST3GAL5,ARHGAP33,LHX2,PICK1,AKAP7,WHRN,CREM,ABCG1,SLITRK5,ARHGEF4,PLXNC1,SEMA4D,FYB1,TRAF3IP2,TXNL4A,LPAR4,GRM8,GUCY1B1,HLF,MAPT,NF1,PDE4D,PIK3R1,PPP5C,GSTCD,ZNF821,MRAS,ASAP3,FHOD3,ST6GAL1,PPP4R3A,IQSEC2,BHLHB9,UGT8" Drug 1318_DN Metrizamide [31112-62-6]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "CDC42BPA,APAF1,ARNTL,NCOA1,CAPN3,FOXN3,SOCS6,TPP1,TMEM184B,HINFP,SIPA1L1,SLITRK5,KIAA0753,DPH1,IGSF6,SEMA4D,TJAP1,MAP4,SETD4,RETREG2,SAMD9,EXD2,CCDC25,TCP11L1,FAM214B,SLC6A8,KDM4B,ZBTB43,CAMTA2,ARHGEF9,TCF4,NSD1,ZNF34,ATP6V0E2,LAMP5,HPS4" Drug 4962_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ADORA1,NME5,SEMA6A,ALK,FAM131A,ARHGAP33,FOXN3,CNTN1,ARMC8,CTH,HIPK3,ELN,APC2,DLC1,SCARA3,TPK1,FYB1,GNG4,NF1,RETREG1,MTRF1L,PTPRO,CNKSR2,PKNOX2,SNCA,KIF13A,ZHX3,ZBTB43,RGL1,SYN2,TK2,CABIN1,PIK3R5,TRIO,SLC17A7,KCNAB1" Drug 6465_DN Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "NDRG3,SRPX,TRMT9B,CDC42BPA,CDC14B,MARK4,KIF1A,CFLAR,CRLF1,SLIT2,ABI3BP,BAG4,SH2B1,PDE4DIP,GREB1,DCAF8,PARD6A,PRELID3A,INPP5K,RASSF8,MAPT,MATK,ZNF862,P2RY1,TMEM104,PTN,FBXW7,MAPK12,SYBU,ARC,IQCE,FBXW11,SLC44A1,TSN,MAP3K12,AAAS" Drug 206_DN celecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,BRAP,ARNTL,HIP1R,TAOK2,VAX2,SULT4A1,PCYT1B,CPS1,C2CD2L,RCAN1,KCTD3,ING4,SRPK3,FGFR1,SEC23B,SLC2A6,NXPH3,IPO5,MITF,MMP16,MYO6,PRKAR1B,ZC3H14,LIMS2,ZBTB43,PHLDB1,PLCB1,OBSL1,CHST8,PARD3,METTL3,VIPR2,SPHK2,GDPD5,LAS1L" Drug 7134_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "PPFIA3,ATP2A2,SCAPER,MYRF,ARHGEF2,CHN2,AKAP5,DTNA,EGFR,RABEPK,ZNF589,DLL3,DENND2A,TMEM8B,CRCP,GLYR1,GPER1,CLASRP,MMP16,MX1,PALM,CNNM2,EMID1,ST6GAL1,FAM214B,SIRT2,SLC22A4,SNCA,CEP68,VPS13A,PLCB1,ASTN2,IQCE,ZFPM2,EMSY,EVI5" Drug 6461_DN Clioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-03 1.00E+00 2.02E-02 2.27E-01 36 199 "ASIC1,BRAP,SEMA6A,APOC1,NUMB,ADAM15,BMP7,CA12,KRIT1,AP4M1,NRG2,SOCS5,PDE4DIP,DAPK3,DNM1,DTNA,TOM1,SCML2,MALT1,TXNL4A,DIDO1,BTN2A1,RNFT2,MAPT,NF1,OXTR,MINDY2,PTK2,RET,SBF1,TROVE2,ITPRID2,TTBK2,ASTN2,MCF2L,ZNF189" Drug CID000025439 NSC3364 Stitch 3.21E-03 1.00E+00 2.03E-02 2.29E-01 24 118 "ADCY6,BRAP,AMPH,ARRB1,C5,B4GALT6,EPS15L1,CLTC,ENTPD4,ABCG1,DNM1,DNM1L,EDN1,EDNRA,RASA4,B4GALNT1,NEU3,HMGCR,MAPT,MAPK3,SMPD3,SLC14A1,NETO1,ST8SIA2" Drug CID004469372 AC1NBK9Q Stitch 3.23E-03 1.00E+00 2.04E-02 2.30E-01 11 39 "CALB1,ARHGEF1,B4GALT6,EIF4G2,KCNMB4,OPA1,EXOSC10,RNASE1,PBLD,STX1A,SYP" Drug CID000100208 Dolastatin 10 Stitch 3.23E-03 1.00E+00 2.04E-02 2.30E-01 11 39 "ABCG2,TUBD1,TUBB3,TUBA8,STMN1,MX1,ABCB1,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000004920 17-isoprogesterone Stitch 3.23E-03 1.00E+00 2.04E-02 2.30E-01 163 1171 "ACTN1,ADCY5,ADCY6,ADCY8,ADD1,AGT,OSBPL6,OSBPL8,SPARCL1,AMH,BIN1,APAF1,APOC1,APOC2,ARHGDIA,ARNTL,CDK13,NCOA1,SLC2A11,BID,BMPR1B,LDLRAD4,CH25H,PRC1,LRBA,CDR1,NOG,CRLF1,CHGB,CHRNA4,ABCG2,COL4A5,COL11A2,TBPL1,NCOR1,NCOR2,ABCG1,CSF1,CSF1R,SIPA1L1,GREB1,DBI,GSDME,EDN1,EGFR,EIF5,IRAK4,TUBD1,ERBB2,ERBB4,ETV1,TUBB3,FDFT1,PPP1R1B,POLR1B,PRKAG2,AGAP3,FLT1,GABRA3,GABRB3,GABRG1,GABRG2,GAD1,MTHFD2,TUBA8,MSTN,GDF9,CYP46A1,GFER,GGT7,GGT5,GHR,PPARGC1A,LYVE1,CRCP,STARD3,LOXL3,GPR12,GPER1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,FAM107A,HBA1,TNFAIP8L3,HMGCR,HP,IGF1,IL6ST,ITGA7,KCNK3,MAT2A,MBP,MMP16,MMP17,NEFH,NPY,NPTX2,OPRL1,OXTR,PCDHGC3,ABCB1,PMP22,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,KLK6,PTCH1,PTPN13,PPP2R3C,PID1,ROGDI,ZNF532,PTGR2,RPS20,HUNK,CLIP1,SAFB,MAPK12,FBXO11,FNDC3A,SYBU,SLC2A5,PDZD2,SOX11,SPP1,PEG10,SST,LARP4,ERBIN,APOM,SYP,CUX2,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA2,THRA,TIMP4,RIMBP2,NR2C2,TUBB2A,SGK3,TUBB1,UBC,UBE2H,UBTF,USP1,CLIP2,XRCC4,SMARCAD1,TUBA1A,HPS4,RTN4,NETO1,AP3B2" Drug CID000000951 noradrealine Stitch 3.23E-03 1.00E+00 2.05E-02 2.30E-01 87 575 "ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,ATP1A3,SLC4A4,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CCK,P2RX6,CBFA2T2,LRBA,CACNA2D2,CHGB,CHRNA4,SULT4A1,COX4I1,CREM,PLCXD3,DMPK,EDN1,EDN3,EDNRA,EDNRB,TUBD1,HSPA12B,OLFM1,TUBA8,MSTN,LOXL3,LPAR4,PLCD4,MAP4K5,ATXN2L,TNFAIP8L3,HMGCR,MMP16,MMP17,P2RY13,NDP,NPY,OPRL1,P2RX7,P2RY1,PIK3C2A,PIK3R1,PKD1,PLCB2,PLCD1,PPARA,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,KLK6,QDPR,RGS3,RYR3,MAPK12,HSPA4L,SNAP25,SST,PLCB1,SYT1,TACR1,ACTR6,PIK3R5,TUBB2A,TUBB1,UBTF,P2RY12,ZNF24" Drug CID000078017 I-As Stitch 3.24E-03 1.00E+00 2.05E-02 2.31E-01 30 158 "AS3MT,APAF1,ARHGDIA,CNR1,HDAC9,DMPK,DYNC1I1,ENO2,PPP1R1B,HVCN1,PPARGC1A,TCERG1,PACSIN2,HP,MBP,OGG1,PDCD2,ABCB1,MAPK7,PRODH,PTPRN,QDPR,FBXW7,ATXN7,FOXRED1,SNCA,SST,PRTFDC1,AAAS,JPH3" Drug CID010425705 lecithin Stitch 3.25E-03 1.00E+00 2.06E-02 2.32E-01 51 306 "ABHD6,SYT13,PITPNM2,AMPD3,APOC1,APOC2,PLA2G4C,SPAG9,DGKI,HECTD1,CNTN1,PLCXD3,DGKB,DGKG,PITPNC1,CHRDL1,DTNB,EPB41,CD320,PRAM1,AGAP2,AGAP3,ATP6V1H,HRASLS5,NEU3,GPR162,LOXL3,PLCD4,HMGCR,MAT2A,MBP,CNTN3,ENPP2,ABCB1,PIK3C2A,PIK3R1,PLCB2,MBOAT7,PRKCB,ATP8B4,SMPD3,SLC12A4,ADHFE1,PLCB1,SYT1,SLC30A4,GDPD5,PLD4,PLSCR4,HRASLS,NETO1" Drug CID000009254 isoxazole Stitch 3.29E-03 1.00E+00 2.08E-02 2.34E-01 14 56 "CA4,ABCG2,MYEF2,ABCC5,PRMT5,GRIA2,GRIK5,GRM2,ABCB1,MAPK10,SLC6A11,SYN2,SYNE1,ARHGAP9" Drug CID000388944 AC1L8WWP Stitch 3.29E-03 1.00E+00 2.08E-02 2.34E-01 14 56 "ABCG2,NCOR1,NCOR2,EGFR,TUBD1,ERBB2,TUBB3,TUBA8,MAP4,MX1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug 3310_UP Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.31E-03 1.00E+00 2.09E-02 2.35E-01 31 165 "CLK4,PLA2G4C,CFLAR,ST3GAL5,CFAP410,CLGN,STOML1,WHRN,RCHY1,CSF1R,SPOCK2,RCAN1,RASGRP1,MBNL2,AMOTL2,TPK1,SRCAP,GRIK5,IL6ST,ITGAM,MINDY2,C1orf54,CLIP1,ZNF821,HSPA4L,SH3BGR,PPM1E,ST6GAL1,WSCD1,TRIM2,VLDLR" Drug CID000071158 acamprosate Stitch 3.34E-03 1.00E+00 2.11E-02 2.38E-01 17 74 "ARNTL,SPAG9,CRY2,CSNK1E,GRIN3A,NR1D2,GABRA3,GABRB3,GABRG1,GABRG2,GGT7,GGT5,GRIN2C,GRIN2D,GRM2,GRM8,OPRL1" Drug CID000001922 8-phenyltheophylline Stitch 3.36E-03 1.00E+00 2.12E-02 2.39E-01 15 62 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,APC,ALDH7A1,P2RX6,GPR162,LPAR4,P2RY13,P2RX7,P2RY1,RNH1,P2RY12" Drug CID000036511 Substance P Stitch 3.36E-03 1.00E+00 2.12E-02 2.39E-01 56 343 "ACHE,ADCY5,ADCY6,ADCY8,AGT,ARHGDIA,CACNA1B,CALB1,CALM1,CCK,CHRNA4,SULT4A1,CNR1,PLCXD3,DMPK,EDN1,EDN3,EDNRB,ENO2,PPP1R1B,GAD1,GFRA2,CRCP,MCHR1,PLCD4,GRIN2C,GRIN2D,TNFAIP8L3,IGF1,LSAMP,KITLG,NPY,NTRK3,OPRL1,CLDN11,PLCB2,PLCD1,MAPK3,PRPH,RET,FBXW7,RYR3,MAPK12,SP2,SP4,SST,SSTR1,SSTR2,PLCB1,SYP,TACR1,UCHL1,VIPR2,NPDC1,SLC17A7,JPH3" Drug 584_UP dimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 3.36E-03 1.00E+00 2.12E-02 2.39E-01 32 172 "PPFIA4,ARRB2,BMP7,CREM,RASSF2,FAM13A,MBNL2,ENO2,FGFR1,RUNDC3A,KCNN1,MXI1,NTRK3,PFKFB3,PFKFB4,PRKAR1B,MAPK3,MASP1,PTX3,SLC25A36,ASAP3,SLC9A5,KDM4B,KDM3A,SPART,JMJD6,MCF2L,CBX5,OSBP2,WIPF1,ZNF189,VPS35L" Drug CID000446872 AC1L9K72 Stitch 3.36E-03 1.00E+00 2.12E-02 2.39E-01 49 292 "ABHD6,PITPNM2,SPTBN4,PLA2G4C,ALDH7A1,BID,SPAG9,DGKI,RAB33A,HECTD1,CNTN1,PCYT1B,PLCXD3,DGKB,DGKG,PITPNC1,CHRDL1,EPB41,PSD2,HRASLS5,PLCD4,GABARAPL2,MBP,PCDH8,ABCB1,PLCB2,PLCD1,PLTP,MBOAT7,PTX3,PEX2,ATP8B4,SMPD3,PEX26,CCDC88A,SLC12A4,ARFGAP1,SPTAN1,SPTB,SEPT8,ARHGEF9,PLCB1,TBL1X,SPHK2,SLC30A4,PLD4,PLSCR4,HRASLS,NETO1" Drug ctd:C545373 ponatinib CTD 3.37E-03 1.00E+00 2.13E-02 2.40E-01 16 68 "CSF1R,EGFR,EPHB1,ERBB4,PTK2B,FGFR1,FGFR3,FLT1,FYN,JAK2,KIT,NTRK2,NTRK3,MAPK3,RET,TEK" Drug CID000001066 quinolinic acid Stitch 3.40E-03 1.00E+00 2.15E-02 2.42E-01 33 179 "ACHE,ADORA2A,APAF1,DDO,CALB1,CALB2,CNR1,CNTFR,DYNC1I1,PPP1R1B,FGF1,GAD1,PPARGC1A,TCERG1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,PACSIN2,TNFAIP8L3,HMGCR,IL6ST,LIFR,NPY,OGG1,QDPR,FBXW7,ATXN7,FOXRED1,SST,JPH3" Drug 2184_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-03 1.00E+00 2.15E-02 2.42E-01 33 179 "ABHD6,BIN1,CDC42BPA,EPB41L5,DDO,CDK10,ZSCAN18,N4BP2L1,CACNA1G,LDLRAD4,SLIT2,CABP1,RIPOR2,DAPK3,MFAP3L,FGF12,GLUL,CACFD1,IRAK3,MAP4,CLDN11,PURG,POU6F1,WDR25,SH3BP2,SMARCD3,SPTB,ZBTB43,ATP10B,SAMSN1,KANK1,BHLHB9,FLRT2" Drug 5074_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-03 1.00E+00 2.15E-02 2.42E-01 33 179 "ASPHD1,APAF1,APOC1,NRP2,CACNA1A,CALB1,CBS,ARHGEF2,WHRN,CTH,HDAC9,COQ7,SYT17,GFER,STMN2,TJAP1,MATN3,NEFM,MTRF1L,PTPRH,PTX3,PID1,RASGRF1,RGS4,KCTD17,RASA3,CPEB3,KDM4B,DDN,SYT1,COBL,KLHL4,VGF" Drug 2928_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-03 1.00E+00 2.15E-02 2.42E-01 33 179 "ABHD6,BIN1,SIPA1L1,SEC14L5,RCAN1,FAM13A,ANKMY1,EYA1,ST3GAL6,OLFM1,GLUL,GRIK5,GSN,IL6ST,ITPKA,MSR1,NINJ2,NPTX1,TREM2,PFKFB4,PGAM2,MARCH1,GTDC1,CPEB3,KDM4B,ZHX3,SPTAN1,SAMSN1,KANK1,TBL1X,SZT2,RPRM,LMF1" Drug 4137_UP Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "NDRG2,AMPD3,DNAH17,SYNJ1,ARHGEF1,CNTFR,COL9A3,CRY2,ARMCX2,ING4,EPHB1,FGFR3,FLNC,GAD1,SESN1,GPER1,GSTM5,AP4S1,ATXN2L,ICA1,KCNJ5,MIA2,CNOT4,LRP12,MAPK7,TRIM68,KCTD17,RPS6KA2,PHLDB1,KIAA1107,ZMAT3,TRIO,DNALI1,KCNAB1" Drug ctd:D003913 Dextroamphetamine CTD 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "ADRA1B,AGT,ATP2A2,MYOM1,BID,CACNA1G,CAMK2B,CCNT1,CDH2,CNR1,CREM,CRHBP,CSF1,EIF4G2,TUBB3,FGFR1,GDF1,GNAL,GPER1,GRM8,NPY,NTRK2,MAPK3,RDX,RGS4,STX1B,SIRT2,SNCA,STX1A,ARC,SYP,SYT5,TACR1,SLC17A7" Drug 2407_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "ALCAM,ALK,AMT,CAPN3,SH2B1,OSBPL3,VCAN,ZNF337,E2F5,RACK1,ZNF589,ALDH1L1,LILRA2,DHX35,LSS,MAN2A2,MAP4,MEF2C,SETD4,NLE1,TMEM231,RNH1,PLPPR3,ARHGAP26,ZBTB43,DDN,CEP68,KANK1,VPS13A,ZEB1,HIF3A,THRA,LAMP5,NAV3" Drug 841_UP resveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "ADRA1D,RGS20,SLC2A11,N4BP2L1,CRY2,PDE4DIP,CTH,GIT2,CELSR3,MBNL2,EGR3,ARMCX1,ST3GAL6,FYB1,SESN1,GRM8,IRAK3,AFDN,SAMD9,TMEM104,C1orf54,CARF,TCP11L1,SCN2B,SH3BGR,FRMPD1,FNDC3A,SYBU,ZKSCAN3,SNCA,TSPYL2,THSD1,SYT5,VIPR2" Drug 1533_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "AMT,APBA2,PPP4R4,ADGRB2,CFLAR,SYNJ2,ARHGEF2,HOMER3,CLIP3,CSF1,JAKMIP2,MFAP3L,CDON,ERCC2,AGAP2,PDLIM5,DISC1,SRCAP,GPER1,GRB10,GSN,HLF,HMGCR,IL6ST,NTRK3,ELOVL2,FNDC3A,FAM214B,TRIM2,SZT2,TK2,ZFP37,NT5M,EVI5" Drug 6953_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "ASPHD1,AMH,BCAS1,STX16,CFLAR,SYNJ2,PLEKHB1,PDE4DIP,CDON,SEZ6L2,ING4,ZNF44,GAD1,INPP5K,PCLO,GRIK5,HNMT,LMO2,MXI1,PFKFB2,SERPINI1,TMEM231,CCDC25,TCP11L1,KDM3A,IQSEC2,CDK19,CEP68,ARHGEF9,TRIM2,CDK20,UBE2H,ZNF23,ZNF45" Drug 5597_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-03 1.00E+00 2.16E-02 2.44E-01 34 186 "LDLRAD4,CFAP410,CA4,ARHGEF2,LY86,NRG2,SNCAIP,CSF1R,PDE4DIP,CTH,FRY,ING4,MAP2,NELL2,NNAT,GPR85,MTRF1L,LRP12,GDPD2,C1orf54,RASGRF1,RFX2,CNKSR2,CXXC4,SNCA,KDM4B,TRIM2,PCDHGB6,PCDHGA10,CRTC1,UGT8,WIPF1,KCNAB1,FAM13C" Drug 5584_DN trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,SEMA6A,LTBP4,CDC14B,ARHGDIG,ARRB1,RGS20,MARK4,NCOA1,ARHGEF2,CRY2,CSNK1E,CNTNAP2,DAPK3,TNK2,FHL1,FAM49B,MSL3,CNTRL,KCNH2,MEF2C,KITLG,MSI1,NF1,PLCD1,PPP2R2B,LRRN3,KCNIP1,SBF1,SMARCD3,MAPKBP1,DOK5,PHLDB1,TPM1,PLSCR4" Drug 4846_UP Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "KIAA1324,CDC42BPA,RGS20,ADAM23,ST3GAL5,COL9A3,HAPLN1,ARHGEF10,DCAF4,DAPK3,ELN,ST3GAL6,ZNF589,OLFM1,FLNC,ATXN2L,KCNB1,MATK,MID1,TAGLN3,NNAT,NPTX1,ENPP2,SMIM7,MTRF1L,RGS4,NLGN1,SNCA,ZC4H2,WSCD1,DOCK9,FAM189A1,TNS1,PIK3R5,TIGD6" Drug 2383_UP Norethindrone [68-22-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ARRB1,PDE8B,ZSCAN18,N4BP2L1,AZGP1,ST3GAL5,DCAF4,ARHGAP24,MYEF2,GSDME,DTNA,MBNL2,RASGRP2,FHL1,GLYR1,FAM107A,ADAMTS6,NXPH3,ICA1,SCIN,KCNJ5,LSS,NF1,NINJ2,PDE4B,PLTP,MASP1,RNASEL,SLC8A1,ZSWIM8,SS18,MCF2L,TBL1X,CUX2,SSBP2" Drug 6022_UP Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "CLK4,SEMA7A,APBB2,CA4,HAP1,ARHGEF1,SRSF11,FAM189A2,CYBB,BRINP1,GSDME,REEP2,BAIAP2,ALDH1L1,SESN1,PCLO,TJAP1,ZNF862,PPM1B,MAPK10,PTH1R,C1orf54,TCP11L1,RPS20,RASA3,PPP4R3A,SMARCC2,PEG10,SYT5,WSCD1,ZMAT3,PARD3,AMACR,FAM155A,VGF" Drug CID000004893 prazosin Stitch 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,CACNA1A,CACNA2D1,P2RX6,CBFA2T2,ABCG2,PLCXD3,EDN1,EDNRA,LPAR4,PLCD4,ATXN2L,TNFAIP8L3,KCNH2,MITF,P2RY13,NPY,OPRL1,P2RX7,P2RY1,PLCB2,PLCD1,PRKCB,MAPK3,PLCB1,P2RY12,NETO1" Drug 1703_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "NDRG2,ALCAM,SLC4A4,RAB28,MFAP3L,MBNL2,RGS17,HSD17B14,BAIAP2,IQCG,EFCAB2,CGREF1,TMEM8B,GPER1,ICA1,INPP5B,KHK,MBP,NRCAM,RETREG1,PLCD1,ING3,ELOVL2,GSTCD,SH3BP2,SLC22A4,ST5,SZT2,ZNF34,TMPO,TRIO,RUNDC3B,XRCC4,VPS35L,EPM2A" Drug 6981_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "MPDZ,SRSF11,LHX2,HOMER3,CDC42BPB,CREM,CSNK1E,SOCS5,GIT2,B3GAT3,FEM1B,EIF5,MRNIP,FGFR1,FGFR3,PRKAG2,NOP56,MALT1,TXNL4A,MUM1,NCAM2,NF1,OGG1,CCSER2,PPP5C,ZSCAN32,RGS3,UHRF1BP1L,JMJD6,IQCE,FBXW11,SATB2,TRIO,ACTR3B,GAN" Drug 4380_DN CP-690334-01 [459212-38-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,BRAP,AMPD3,CDC42BPA,APLP1,SEMA4G,RGS20,CFLAR,GYG2,CACNA1I,CNTFR,WHRN,CPS1,AKAP12,ABCG1,CSF1,MFAP3L,RUSC2,DMPK,HIPK3,PCDH17,BTN2A1,ICA1,ITPKB,KHK,KIT,NPTX1,NLE1,PRODH,RIPOR1,TRIM68,LIMCH1,PCDHA6,PARD3,EVI5" Drug 4801_DN Digitoxigenin [143-62-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "PPFIA3,ST3GAL5,KRIT1,ARMC8,RUBCN,ZBTB24,RHOBTB1,SACS,DPH1,ANKRD46,EGR3,ARMCX1,INPP5B,THYN1,PDCD2,PIK3R1,RETREG1,NLE1,PLEC,PTCH1,ZSCAN32,RAD51D,RGS3,RNASEL,ZC3H14,MAP6D1,ZNF302,KANK1,ZC3H4,ASTN2,FAM208A,TBL1X,UBTF,ZIC1,ZNF23" Drug 7147_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "CDK10,MADD,NRXN3,CNTNAP2,RUSC2,OPTN,EIF5,SEMA4D,CGREF1,FYN,GAD1,ERAP1,GFER,TDRKH,INPP5B,MAP4,MAPT,ADAM22,MYO9A,SETD4,ZSCAN32,PTPRH,MAPK12,PPP4R3A,LIMS2,SLC6A8,SLC14A1,ZBTB43,VPS13A,TRIM2,DOCK9,CABIN1,RUNDC3B,TRPS1,EVI5" Drug 3799_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ABHD6,ADCY6,BIN1,PPP4R4,RASL11B,SYNJ2,C5,TAOK2,HOMER3,NRG2,DAPK3,DTNA,MBNL2,ING4,ZNF589,TDRKH,GPR37,ATXN2L,SHISAL1,SCIN,IL6ST,IL12A,LIFR,MAPT,SCAMP5,NF1,PIK3R1,ZNF671,CSRNP3,TSNAXIP1,TIAM1,VGF,LAT2,XRCC4,PLSCR4" Drug 2561_UP Dicumarol [66-76-2]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "APOC1,LGR5,ARHGDIG,CACNA1G,CA8,CACNB4,CDH2,DLGAP1,LHX2,NRG2,CSF1,RIPOR2,DAPK3,SPOCK2,KIAA0319,SPOCK3,EXOG,DLC1,NSG1,GLI2,GNAL,KCNB1,KCNJ5,PDE4D,PPP1R1A,CNNM2,PTPRB,KHDRBS2,ZNF821,SYT5,DNMBP,TBCEL,PCDHGA10,TRO,DNALI1" Drug 2540_DN Podophyllotoxin [518-28-5]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ADRA1D,ARRB1,ADAM15,C5,CAPN3,SCARB1,SPOCK3,NR1D2,CDON,MRNIP,RASGRP2,RAB40B,SLC2A6,VSIG4,IDH3A,MYT1,NEFH,NNAT,SLC11A2,TMEM231,KHDRBS2,RET,PLPPR3,HSPA4L,FRMPD1,DZIP1,DDN,ZC4H2,KANK1,CDK20,TRIO,CFAP298,NT5M,NAV3,FAM13C" Drug 6422_UP STOCK1N-35215; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ADRA1D,BIN1,APBB2,ARNTL,DNAH17,SCAPER,PLAA,ARHGEF6,AKAP7,CREM,ENTPD4,DTNA,EDN1,EDNRB,GSTM5,RASSF8,ICA1,IL6R,KCNQ3,L1CAM,NF1,SLC11A2,NLE1,MBOAT7,ZSCAN32,C1orf54,RIC8B,SS18,RGL1,ZEB1,PCDHGB6,ZNF34,SPHK2,SLC30A3,PRDM10" Drug 5315_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ALCAM,LTBP4,GAS7,APOC1,SLC4A4,ADAM23,CFLAR,BMP7,FAM189A2,QKI,HOMER3,CNTN1,SMARCAL1,PDE4DIP,GIT2,EGR3,VPS26C,FGF12,PDLIM5,FYN,GRB10,ICA1,MATK,NKAIN1,SH3BGR,FUZ,FNDC3A,SPTAN1,THSD1,ARC,MCF2L,ICAM5,CABIN1,SEMA3B,RNF170" Drug 4394_DN Levodopa [59-92-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ADORA2A,AMT,APLP1,MARK4,CFAP410,SPAG9,ARHGEF2,MFAP3L,EXOG,HIPK3,FGF13,FHL1,GLYR1,RAB30,PCLO,CNTRL,ICA1,TJAP1,IL6ST,KCNN2,KITLG,ADAM22,ZNF862,NF1,ZSCAN32,PPP4R3A,FAM214B,LIMCH1,NXT2,MCF2L,EXOC7,TRIO,VLDLR,MAP3K12,ST7" Drug 2899_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,ADRA1D,AK2,GAS7,ARHGDIG,SLC2A11,CFLAR,SCAPER,ARHGAP33,PICK1,NRG2,CPS1,ENTPD4,SPOCK2,ERBB2,DLC1,OLFM1,NEU3,GPER1,KCNH2,KIF5A,NNAT,CNOT4,SLC25A23,PRODH,FRMPD1,IQSEC2,JMJD6,TCF4,KIAA0930,TMEM121,TRIO,TRPM2,GDPD5,ITM2C" Drug 997_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "C1QTNF3,KCNAB2,APC,PPFIA3,MARK4,CFLAR,SGCE,C5,BAIAP3,CNTN1,LRIG1,ARMCX2,TOM1,MTSS1L,F5,COPS8,HTATSF1,POLL,INPP5B,LSS,MAP2,LYRM9,ZNF862,CNOT4,GRAMD1C,FAM184A,RPS20,PREX2,PPP4R3A,SLC6A8,VPS13A,PLCB1,VAV1,EPM2A,GAN" Drug 6732_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "AP2A2,AGT,CFAP410,CREM,ABCG1,CTH,SEC14L5,MFAP3L,EDNRB,HIPK3,FCF1,ING4,COQ7,FGFR1,GAD1,NEU3,ZNF276,HPGDS,GPER1,HNF4G,SHISAL1,KITLG,AFDN,RETREG1,SNAP25,PDZRN3,SPP1,ASTN2,TCF4,DOCK9,DNAH7,TK2,ZNF24,PRDM10,EPM2A" Drug 4690_DN Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,DOC2A,FAM131A,PPFIA3,RGS20,LDLRAD4,UBE2L6,SH2B1,BRINP1,SUGP2,ACSL4,TRAF3IP2,SEPT9,GFER,KPNA5,MBD1,MPP2,NF1,SAMD9,PTN,RNASEL,FNDC3A,KIF13A,EXOC7,ZEB1,TRIM2,RPGRIP1L,SLC44A1,PARD3,FAM155A,VIPR2,DNALI1,KCNAB1,KAT6A,TIGD6" Drug 2721_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "AMPD3,KCNAB2,KIF1A,MTMR2,C5,CACNA1A,EPS15L1,RAB28,NRG2,CTH,RUSC2,NR1D2,DTNA,E2F5,HIPK3,EIF1,MTSS1L,PDLIM5,CAMKK2,KHDRBS3,CSPG5,GNG4,IL6ST,SMAD1,MAP4,NF1,NNAT,POLG,SH3BP2,PREX2,SLC11A1,TROVE2,ZNF34,KAT6B,LMF1" Drug 3262_UP "Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "MARK4,WASF1,CFAP410,CACNA1A,USP2,STOML1,WHRN,NCOR1,C2CD2L,SEZ6L2,CNNM1,PRRC2B,GPER1,CACFD1,GRM8,L1CAM,ZNF862,PALM,MAPK7,KCTD17,SH3BP2,AMBRA1,DHX30,ARFGAP1,SMARCA4,TBCEL,SYNE1,OBSL1,WBP2,TRIO,VGF,WIPF1,KLC2,SPHK2,KAT6A" Drug 6898_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "APAF1,ZBTB10,STX16,RAB29,KYAT1,VAX2,CREM,SH2B1,SOCS5,DCAF8,LYPD1,BAIAP2,MPP6,OGA,SRCAP,MALT1,POLL,KCNN1,KHK,NEK1,NFYA,SUPT20H,FBXO11,PPP4R3A,BTBD7,SPART,LHPP,TRIM2,RPRM,VGF,XRCC4,ZFP37,ZNF24,MAP3K12,HPS4" Drug 4286_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,NME5,C1QTNF1,APC,CDK10,PPP4R4,SYNGR3,CHN2,IQCK,ARMC8,CRMP1,ARMCX2,DMPK,DTNA,DUSP9,ERCC2,ETV1,FGFR1,BAIAP2,HPCAL4,FLT1,DLL3,DENND2A,POLL,NTRK2,PALM,PDE4A,PPP5C,MAPK12,KDM4D,ELMO2,CDK5RAP2,SPTB,VIPR2,SEMA3B" Drug 3242_DN Carcinine [56897-53-1]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "AK2,EPB41L5,GAS7,APOC1,ARRB1,KIF1A,MPDZ,CFLAR,SYNJ2,SCARB1,UBE2L6,CSF1,CTH,PPP6R2,MAML1,SUGP2,BAIAP2,OGA,HNMT,TJAP1,KCNF1,MAP4,MPP2,PRKAR1B,SLC25A36,NEK11,RPS6KA2,SBF1,ZFP30,ABLIM3,DOP1A,FBXW11,PARD3,REEP1,SEMA3B" Drug 431_DN troglitazone; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "NDRG2,LGR5,STX16,BMPR1B,CACNA1I,CBFA2T2,TAOK2,ZNF804A,RCAN1,SUGP2,EGFR,EPHB1,ETV1,FYN,NEU3,TXNL4A,AP4S1,MAPT,MEF2C,PTX3,RGS12,RNASEL,SATB1,ATXN2,SIRT2,MAPKBP1,CLASP2,WSCD1,KIAA0930,CABIN1,TNS1,FAM155A,KCNK12,SH3GLB2,GDPD5" Drug 4558_DN CP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASPHD1,AP2A2,NME5,BIN1,KCNAB2,SEMA4G,ARHGEF1,ARMC8,SLC4A8,CSNK1E,FAM131B,MFAP3L,RUSC2,LYPD1,SPEG,ANKMY1,EZH1,TRAF3IP2,DENND2A,SYT17,DISC1,HAS2,GIT1,NDP,STRN3,PTPRN2,DZIP1,KDM4C,CDK19,ZBTB43,SPART,TBL1X,DNAH7,XRCC4,HPS4" Drug 3814_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "APC,NRP2,CFLAR,BMP7,CBS,SEPT7,ARHGAP33,CACNA2D2,FAM13A,PRELID3A,OGA,GNG4,IL6ST,INPP5B,ITGA7,LSS,OGG1,PIK3R1,PLCD1,MINDY2,GRAMD1C,MCMBP,TRAPPC13,SUPT20H,PREX2,ZNF334,BTBD7,OGDHL,SNCA,TBCEL,GPR161,VIPR2,TFIP11,PCBP4,DPF3" Drug 544_UP radicicol; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "NDRG2,ADORA2A,EP400,SYNJ2,SLC25A14,TAOK2,TMEM184B,CNTFR,SPOCK2,DTNA,IRAK4,BAIAP2,IP6K2,ANKFY1,ATP2C1,CELF1,MALT1,CACFD1,MUM1,MARK3,MBD1,GIT1,SETD4,MBOAT7,PRKACB,MAPK3,RNASEL,STUM,HSPA4L,ZFP30,SH3GL3,INTS9,CDK19,STX1A,ZKSCAN5" Drug 1667_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASPHD1,AK2,LTBP4,SYNJ2,CFAP410,TBC1D5,PARD6A,FEM1B,EIF5,FGFR3,BAIAP2,GRB10,MUM1,KCNH2,KHK,LIG4,MAP4,GIT1,SMIM7,MBOAT7,PRKAR1B,TMEM104,SAFB,EPN2,ARFGAP1,MAPKBP1,ZHX3,PHLDB1,JMJD6,PLCB1,EXOC7,KIAA0930,CABIN1,REEP1,GDPD5" Drug 7238_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "LGR5,ADGRB3,SCAPER,GYG2,CACNB4,ARHGEF2,AKAP7,CSF1R,HDAC9,SLC12A6,TENM1,BAIAP2,FHL1,FLNC,OGA,SPACA9,GRM8,KCNN1,KCNN2,LIG4,AFDN,CNOT4,LRRN3,SUGCT,FAM214B,KANSL3,SLC11A1,PCDHA5,CHST8,AMACR,WIPF1,LAT2,ITM2C,FAM13C,PHTF2" Drug 6103_UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ADD2,LTBP4,BEGAIN,BIN1,RGS20,SGCE,SYNGR3,ENTPD2,LY86,SNCAIP,ARHGAP24,DAPK3,DBT,EDN1,ETV1,PDLIM5,FYB1,GATM,RUNDC3A,PRUNE2,TPPP,GSN,IRF8,ZNF862,NF1,PURG,PPARA,ARHGEF40,ZSWIM8,SPTAN1,OBSL1,ZFPM2,GPR161,UBE3A,KCNAB1" Drug 1988_UP Captopril [62571-86-2]; Up 200; 17.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "SPOP,SHROOM2,CDK10,MADD,SLC4A4,WASF1,CACNA1A,FOXN3,QKI,PREPL,SPOCK2,DBN1,DPYSL2,CELF1,STAU2,RAB30,GPR12,MUM1,OPA1,PDE4A,RETREG1,PLCD1,MAPK3,VPS13C,ZNF821,FAM102A,KBTBD4,ARFGAP1,KDM4B,SPTAN1,SEPT8,STX1A,TACR1,TCF4,TSN" Drug 7052_DN 0316684-0000 [391209-55-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "SEMA6A,ALCAM,APBB2,STX16,RIPK1,ADAM15,CFLAR,QKI,DAPK3,DBT,NR1D2,FEM1B,FCF1,RASGRP1,EGR3,TNK2,ANKFY1,ARFIP1,GLYR1,RAB30,IL6ST,LIG4,MBNL1,PIK3R1,PLEC,MINDY2,PPP5C,TCP11L1,TIAM1,TMPO,TRIO,LMF1,ZBTB14,NDRG4,PHTF2" Drug 4596_DN Lidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "APC,ARNTL,SYNGR3,CHN2,PLAA,BAG4,CTH,FCF1,YAF2,EGFR,IRAK4,RGS17,SEC24B,FHL1,ANKFY1,TRAF3IP2,SYT17,SHISAL1,INPP5B,NDP,NFYA,CNOT4,SERPINI1,PLXNB1,PPP5C,MAPK7,AMBRA1,PEX26,ZBTB43,NXT2,SYPL1,SSBP2,WIPF1,XRCC4,PHTF2" Drug 6753_DN Caffeic acid [3331-39-5]; Down 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "NDRG3,CDK10,ARHGDIG,ARRB2,ATP1A3,STX16,KIF1A,CBFA2T2,ARHGEF2,RAB28,NRXN3,TBC1D5,BRINP1,RUSC2,CELSR3,ETV1,RRAGB,ST3GAL6,FCGRT,ANKFY1,ZNF44,GCNT2,GPD2,KCNN1,NF1,PLXNB1,MAPK7,FBXW7,CLIP1,FAM214B,CCDC88A,ZNF667,TRIO,UGT8,PHTF2" Drug 4431_DN Rapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ASIC1,ADD2,APLP1,ADGRB2,CHN1,HOMER3,ARMC8,CREM,OSBPL3,SOCS5,ARHGEF4,STX2,VPS26C,FGFR1,DENND2A,HAS2,HSF2,KHK,PFKFB2,PPP5C,PRKAR1B,C1orf109,PTX3,RPS6KA2,SAFB,SMARCD3,SYT1,COBL,CRTC1,TNS1,EVI5,CIAPIN1,FIP1L1,PDSS2,PHTF2" Drug 4226_DN "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "CDC14B,ADGRB2,RAB26,ENTPD4,VCAN,EDN1,PLXNC1,RGS17,SEMA4D,CINP,FAM49B,FYN,SEPT9,RUNDC3A,KCNMB4,ATXN2L,MAPT,AFF1,OGG1,PDE4B,PLXNB1,PPARA,MAPK7,SAMD9,ZSCAN32,PTPRB,ZNF821,FRMPD1,PPP4R3A,KANSL3,BTBD7,TPM2,WNT7A,XRCC4,TIGD6" Drug 5351_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "AP2A2,ALCAM,KCNAB2,EPB41L5,BCL7A,CFLAR,KSR1,SCAPER,CA12,CAMK2B,B4GALT6,TAOK2,QKI,PDE4DIP,GIT2,MED12,ACOT8,DTNA,FECH,FER,RASSF8,HNMT,IPO5,MAP4,TM6SF1,ZNF862,RETREG1,PLCD1,LRP12,TMEM104,ANKRD6,BTBD7,ASTN2,EXOC7,ZNF34" Drug CID006857413 AC1OAGKW Stitch 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "SYNJ1,SYNJ2,BTK,MTMR2,CCK,DGKI,CLTC,CSF1,PLCXD3,DGKB,DGKG,EDN1,EGFR,ERBB4,FOXO3,GSN,IGF1,NCF2,OCRL,PDPK1,PIK3C2A,PIK3R1,PLCB2,PLCD1,PLCL1,PLTP,SH3KBP1,MAPK3,PTK2,SBF1,HSPA4L,SGK1,PLCB1,ACTR6,PIK3R5" Drug 4321_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "NME5,ALDH7A1,SRSF11,CRMP1,CNTNAP2,FCF1,CINP,DLL3,KCNMB4,RASSF8,AGFG1,IL6ST,KCNN1,MAP4,MMP16,NFIX,NTRK2,STRN3,MAPK7,PTN,C1orf54,KCTD17,KIRREL1,FBXO11,LIMS2,CCDC88A,TBL1X,TCF4,DICER1,TMPO,VIPR2,SPHK2,ZBTB38,EVI5,KCNAB1" Drug 6802_DN Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.46E-03 1.00E+00 2.16E-02 2.44E-01 35 193 "ALCAM,CDK13,SCAPER,PLEKHB1,PLAA,PICK1,PDE4DIP,ZNF337,GIT2,DTNA,RACK1,FER,BAIAP2,OGA,GLYR1,GNG4,DIDO1,IL6ST,MIA2,NNAT,PPP5C,CEP97,MSANTD2,RET,GTDC1,MAP6D1,SMARCA4,RBM34,ARHGAP26,THSD1,NXT2,TNS2,METTL3,SEMA3B,PCBP4" Drug ctd:D059808 Polyphenols CTD 3.46E-03 1.00E+00 2.16E-02 2.44E-01 71 455 "SYN3,ADRA1D,GAS7,ARRB2,CADPS,ASPA,ATP1A3,HCN2,NRP2,BID,CDC25B,NRXN3,CNGA3,CABP1,HAPLN1,ABCG1,CRYM,PDE4DIP,ERC2,CYBB,RASSF2,DGKB,DBN1,CD99L2,CDON,ABCC5,EDN1,TNK2,CEP78,OLFM1,HPCAL4,POMT1,ERAP1,SYT17,GATM,NEU3,PPARGC1A,GLUL,MCHR1,GRIK5,HAS2,HNMT,HSF2,IL12A,KCNQ3,MARK1,SCAMP5,MPP2,MYCN,NFE2L2,NTRK3,OXTR,PDPK1,PFKFB2,PFKFB3,PFKFB4,NECAB2,MAPK3,PRPH,PTCH1,RGS3,TMLHE,TNFRSF19,SIRT2,SEPT3,TACR1,SIRT1,ZFP37,KCNAB1,FZD3,GJC2" Drug 6075_UP Delsoline [509-18-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "APAF1,PPP4R4,RGS20,N4BP2L1,BTK,GYG2,SNCAIP,SPOCK2,EDN1,FAM13A,ERBB2,ZNF589,FGFR1,OGA,SRCAP,GLYR1,GRIK5,AP4S1,ATXN2L,ITPKA,KCNB1,SMAD1,NEFM,NPTX2,PFKFB2,RETREG1,CEP41,RELN,RFX2,RGS12,RORB,SLC11A1,SPTAN1,TEK,PIK3R5,EPM2A" Drug 5603_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NDRG2,GAS7,PDE8B,SYNJ1,CAMK2B,SOCS6,CRY2,MFAP3L,TOM1,TNK2,HSD17B14,DLC1,FGFR1,FAM49B,TPK1,ALDH1L1,ADAM28,TXNL4A,GRB10,ADAMTS13,GSTM5,HLF,MEF2C,ZNF821,SH3BP2,FAM214B,ZHX3,RBM26,PHLDB1,TBCEL,CRTC1,SLC44A1,TNS1,PLPPR2,REEP1,MAP3K12" Drug 3056_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "SPARCL1,MYOM1,MPDZ,SYNJ2,BAIAP3,SLC16A4,ARHGAP33,SOCS6,RAB26,PDE4DIP,PLEKHA1,EPB41,RRAGB,OLFM1,BAIAP2,GABRA3,GAD1,SIGLEC8,GRIN2C,MAPT,ADAM22,MYH3,PCDH9,NUDT11,MAP6D1,SCN7A,IZUMO4,ASTN2,TRIM2,PHF24,TK2,RIMBP2,TRO,LMF1,VSNL1,KCNAB1" Drug 6449_DN Rolipram [61413-54-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "AK2,SEMA6A,AMH,APBA2,CDK10,SIPA1L1,PDE4DIP,GREB1,GIT2,LYPD1,TOM1,GPHN,SCML2,FHL1,DISC1,INPP5K,MALT1,MAP4K5,RASSF8,IDH3A,FAM69A,KCNH2,MGAT3,ZNF862,NF1,NPR2,NPTX1,LRP12,PPP5C,TMEM231,PEX26,ZKSCAN3,ZBTB43,TACC1,SSBP2,KCNAB1" Drug 1601_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; HL60; HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NDRG2,AMT,APOC1,CDK10,BMP7,GYG2,CALB2,FOXN3,NCOR1,DBN1,RABEPK,VPS26C,FKTN,GDF9,PRDM5,CLASRP,GSTM5,MAP4,ADAM22,SETD4,OCRL,PDE1C,ZFYVE21,MBOAT7,MINDY2,SAMD9,CLIP1,CCDC88A,SLC11A1,MAPKBP1,TSPYL2,POGZ,EXOC7,FLRT2,VSNL1,SLC17A7" Drug 3057_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADGRF5,SPARCL1,SEMA6A,ANK2,PPFIA3,CDC14B,FUBP1,CACNA1I,CACNA1G,LHX2,SEC14L5,ZNF337,DGKG,SRPK3,EPB41,ERBB4,APC2,NEU3,MSTN,ZNF276,GPR75,GNAL,MCHR1,PCLO,MYO7A,NF1,FSD1,DCHS2,KLK6,PTH1R,CRTAC1,RGS12,KLHDC8A,MAP6D1,SLC19A3,AP4E1" Drug 591_UP "N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Up 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADD2,NCOA1,EIF4G3,CBFA2T2,TBRG4,ENTPD4,PPP6R2,TBC1D5,DAPK3,FEM1B,GPHN,FGFR1,TRMO,SEPT9,LILRA2,CLASRP,ICA1,KCNJ5,KIF2A,MAPT,MBP,NELL2,NFYA,NNAT,MAPK3,PRODH,PRPH,SBF1,SH3BP2,AMBRA1,ZBTB43,NXT2,CEP68,EXOC7,WSCD1,WNT7A" Drug 3577_DN Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "CDC14B,KIF1A,CA12,SCARB1,SOCS6,SULT4A1,ENTPD4,LRIG1,CSNK1E,PDE4DIP,GIT2,EDNRA,ANKMY1,ATP2C1,PRELID3A,SEPT9,CNTRL,HNMT,ICA1,IL6R,MAP4,ADAM22,NEK1,FAM184A,GTDC1,CCDC88A,LIMCH1,SOX3,EXOC7,KIAA0930,DICER1,CABIN1,RUNDC3B,PLPPR2,XRCC4,SMIM8" Drug 453_UP "indomethacin, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NDRG2,ALCAM,PPFIA3,FUBP1,MTMR2,P2RX6,CNTFR,AATK,CSF1R,EGR3,MRNIP,POMT1,ZNF276,ADAMTS13,CACFD1,JAK2,KCNB1,PACRG,TM6SF1,AFF1,NF1,PCDHGC3,PDE1C,RETREG1,POLG,FSD1,RGS3,RNASEL,TCP11L1,ATXN2,AMBRA1,TMCC1,ZHX3,SSTR2,TIAM1,SLC17A7" Drug 4605_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "AK2,PPP4R4,RHBDL1,FAM149A,ABI3BP,RGS6,EDNRA,ETV1,ANKMY1,FGFR1,AGAP2,NSG1,FYB1,GABRA3,GRM8,HNMT,LYRM9,NEFM,PIK3R1,RETREG1,STRN3,MINDY2,SNRK,MARCH1,TCP11L1,TRAPPC13,ANKRD6,ARHGEF40,BTBD7,IZUMO4,ARHGAP26,ASTN2,MCF2L,PHF24,TLR4,GAN" Drug 4646_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "RALGAPA1,AMPD3,EPB41L5,NRP2,KSR1,CACNA1G,HAP1,LARGE1,NRXN3,COL9A3,SUSD5,MFAP3L,EDN3,ABCA8,FYB1,GAD1,ALDH1L1,KCNF1,KCNN1,ADAM11,LYRM9,NEFM,NF1,NOVA1,NTRK3,KHDRBS2,TCP11L1,MRAS,SH3BP2,SLA,HECW1,TAL1,SLC44A1,FLRT2,NT5M,KCNAB1" Drug 6789_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "APC,KIF1A,SYNJ2,CAMK2G,SLIT2,LHX2,BAG4,CSNK1E,ARHGAP32,GIT2,MFAP3L,DTNA,PCOLCE2,SRCAP,HTATSF1,AGFG1,INPP5B,NF1,SLC11A2,OGG1,RETREG1,PLEC,SMIM7,PRODH,PTCH1,TCP11L1,RXRA,SGK1,SMARCC2,UHRF1BP1L,RBM26,EXOC7,TNS2,TRIO,LMF1,PHTF2" Drug 4820_UP Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "TRMT9B,N4BP2L1,ADGRB3,KSR1,BAIAP3,RHBDL1,CLDN10,CSF1,RIMS2,DCAF4,SPOCK2,BRINP1,SPOCK3,DMPK,LRRC17,ANKMY1,F5,ST3GAL6,DENND2A,PCLO,IGF1,TJAP1,KCNH2,AFDN,NF1,SAMD9,RGS12,ZFP2,MRAS,SLC2A5,CCDC88A,SLC11A1,CLSTN2,R3HDM1,FAM155A,DNALI1" Drug 7455_UP Panthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ALCAM,AMPD3,BIN1,FAM131A,PPFIA3,KIF1A,SYNJ2,CACNA2D1,CAMK2B,CAMK2G,CBFA2T2,CRLF1,CREM,PHF20L1,TNK2,ZNF589,SEMA4D,EFCAB2,SYT17,HLF,MMP16,LYRM9,MBOAT7,PRKCB,RIPOR1,RNASEL,FBXW7,SBF1,SMARCD3,UNC5B,ELOVL4,MCF2L,THRA,LAT2,SLC30A3,KCNAB1" Drug 1144_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "AMT,APBB2,ARNTL,ADAM15,THSD7A,CAMK2B,FOXN3,AKAP7,CREM,DAPK1,KIAA0753,RUSC2,EGR3,FER,FHL1,PDLIM5,ERAP1,SRCAP,GLYR1,SCAMP5,MX1,NEK1,PLCD1,PTN,PTPRN2,ZDHHC4,RPS6KA2,SAFB,SEC14L1,SLC11A1,TMPO,PARD3,NPDC1,SPHK2,PARP11,PHTF2" Drug 2167_UP Benzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "LGR5,DNAH17,ADGRB1,FUBP1,CNTFR,CREM,CRYM,AATK,VCAN,GSDME,HIPK3,C3orf18,FGFR1,FHL1,PDLIM5,MAP4,ZNF862,NNAT,PGAM2,PLCD1,PPP5C,PTPRN2,RIPOR1,NEK11,TCP11L1,SBF1,GALNT10,ANKRD6,SMARCD3,KDM4B,ATP10B,SS18,TACR1,CDK20,WIPF1,ZFP37" Drug 4014_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADRA1D,APC,SEMA4G,DNAH17,SYNJ2,TAOK2,ARHGAP22,WHRN,CRMP1,MFAP3L,MRNIP,MTSS1L,EZH1,FGF1,AFF2,MSL3,POLL,ICA1,SHISAL1,MAPT,ADAM22,NOVA1,SNRK,ZCWPW1,ENOX1,KHDRBS2,KCTD17,ZNF821,AMBRA1,PKNOX2,ZNF667,SNCA,TSNAXIP1,THRA,RPRM,SH3GLB2" Drug 3010_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NDRG3,APAF1,ADAM15,SYNJ2,CACNB4,SCARB1,CSNK1E,SLITRK5,ZNF337,HIPK3,FAM13A,PLXNC1,C3orf18,CAMKK2,CELF1,IPO5,LSS,ENPP2,PLCB2,DEF8,PTN,TRIM68,RGS3,CLIP1,SCN2B,FAM214B,ARHGEF40,BTBD7,TMCC1,SS18,NPL,ZNF32,ZNF45,ZNF74,MPPE1,PHTF2" Drug 2127_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADCY6,APBB2,QKI,WHRN,ARHGEF4,DCAF4,STX2,FGF1,DENND2A,GAD1,ZNF276,BTN2A1,BACH2,ICA1,TJAP1,IL6ST,JAK2,IPO5,GIT1,CNOT4,CNNM2,SH3TC2,MAPK12,DZIP1,SAMSN1,TTBK2,COBL,IQCE,SMG6,KIAA0930,TIAM1,MAP3K12,EMSY,HPS4,KCNAB1,PHTF2" Drug 2905_DN Cyclopenthiazide [742-20-1]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ASIC1,ABHD6,APC,SLC4A4,ADAM23,AZGP1,LHX2,EPS15L1,PDE4DIP,ARHGAP32,MBNL2,C3orf18,RASGRP2,ZNF549,F5,CGREF1,SRCAP,MSL3,POLL,PCLO,PADI2,MAP4,MATK,MBNL1,MYT1,CCSER2,PLCL1,BEND5,ZNF667,IZUMO4,SPTB,ZC4H2,TPM2,FLRT2,MKRN3,GDPD5" Drug 3130_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "MTUS1,BMP7,SYNJ1,FUBP1,CBR1,KRIT1,COL9A3,TM9SF4,PARD6A,RRAGB,HPCAL4,ALDH1L1,SRCAP,ADAM28,PCDH17,ZNF276,HPGDS,PRUNE2,GRIK5,ITPKA,PLXNB1,WDR25,PTPRN2,PBRM1,NEK11,TCP11L1,MAP6D1,ZNF667,ZSWIM8,IZUMO4,ASTN2,MCF2L,CRTC1,FLRT2,MAP3K12,EMSY" Drug 5355_DN Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ASPHD1,PPFIA3,BCL7A,KRIT1,LRRFIP1,FOXN3,LHX2,QKI,COL4A5,AKAP12,ARHGEF10,USP6NL,DCAF8,LYPD1,MED12,EPB41L2,GAA,ARFIP1,GHR,GPR37,BTN2A1,MUM1,MAP4,MEIS2,SETD4,PMP22,PCMTD2,SPART,SS18,TACC1,IQCE,TRIO,LMF1,PCBP4,EPM2A,MARCH8" Drug 2769_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADD2,ALCAM,LTBP4,CDK13,MARK4,CFLAR,ST3GAL5,SYNJ2,MTMR3,CACNA1I,KALRN,ARHGEF1,OSBPL3,CDON,SNX29,FER,FHL1,KHDRBS3,SRCAP,GFER,ELOVL5,IL6R,MAP4,MGAT3,MID1,AFF1,ADAM22,P2RX7,ELOVL2,C1orf54,ZDHHC14,RGS3,CLSTN2,SAMSN1,EXOC7,CRTC1" Drug 6227_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NME5,ARHGDIG,ST3GAL5,LDLRAD4,CACNA1A,CNOT8,CLCN3,QKI,PPP6R2,ING4,SRCAP,GRB10,HSF2,IL6ST,ITPKB,KHK,MAPT,TAGLN3,LYRM9,NEFH,PCDH9,RGS3,RNASEL,ROBO1,EMID1,SH3BP2,SSTR2,WSCD1,SLC44A1,KAT6B,TPM2,TRPM2,ZBTB14,MAP3K12,SEMA3B,MPPE1" Drug 2939_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ABHD6,MTUS1,PKP4,MARK4,C5,CAPN3,ARHGEF1,ENTPD6,IQCK,CRY2,SLITRK5,MAML1,ECM2,E2F5,PCOLCE2,EIF1,RASGRP2,SEMA4D,ITGAM,LIG4,MATK,MEF2C,NRCAM,OGG1,SNRK,RET,MRPS18A,ZNF821,STX1A,VPS13A,RPGRIP1L,SYNE1,TRPM2,PLPPR2,PRDM10,PHTF2" Drug 6266_UP Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "MPDZ,MTMR2,SCARB1,QKI,FAM169A,GREB1,LYPD1,PARD6A,TMCC2,RCAN1,EGR3,RGS17,STX2,BAIAP2,SIGLEC8,IL6ST,KCNN1,MAP4,PDE4A,RETREG1,MAPK7,ELOVL2,RGS12,GSTCD,SGK1,FBXO11,NUBPL,ZSWIM8,SPTAN1,TRIM2,VIPR2,XRCC4,ZNF45,ZNF189,MAP3K12,EPM2A" Drug 6356_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "PPFIA3,CASK,CFLAR,MTMR2,SPAG9,CDH2,QKI,ARHGEF4,ZNF337,MATR3,GIT2,ARMCX2,FCF1,USPL1,FER,TMEM8B,KIF2A,MAPK9,RIPOR1,CLIP1,SUPT20H,AMBRA1,SMARCC2,TTC17,TMCC1,KDM4C,TEX2,ARHGEF9,ANKRD12,TCF4,METTL3,WNT7A,NDRG4,ZFAND5,ACTR3B,ADAMTSL3" Drug 1666_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ALCAM,AMPD2,AMT,APOC1,CDK10,RIPK1,KIF1A,MTMR2,CRLF1,SOCS6,TAOK2,PLAA,SLC4A8,DCAF8,HDAC4,MAML1,CNNM1,FGFR1,SYT17,INPP5K,SRCAP,INPP5B,MAP4,NFYA,NPR2,SLC11A2,PLXNB1,ABLIM3,PEX26,MAPKBP1,EXOC7,TMEM121,TIAM1,REEP1,GDPD5,URM1" Drug 6665_DN Famotidine [76824-35-6]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "TRMT9B,SHROOM2,SYNGR3,B4GALT6,TAOK2,HAPLN1,VCAN,PDE4DIP,ARHGEF4,KIAA0753,TOM1,ABCC5,COQ7,DLL3,DENND2A,GAD1,B4GALNT1,LIG4,MAPT,MPP2,PLXNB1,PRKAR1B,GRAMD1C,PTCH1,PTPRE,GSTCD,RPS6KA2,RXRA,AMBRA1,TMCC1,UNC5B,IQSEC2,KIAA1107,NSD1,CABIN1,FZD3" Drug 7166_UP Tomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NME5,LTBP4,AZGP1,GYG2,BAIAP3,COL4A5,LYPD1,CDON,RCAN1,MBNL2,RASGRP2,NRN1,BAIAP2,FHL1,EFCAB2,CGREF1,SLC2A6,KCNJ5,KPNA5,LIG4,TM6SF1,MPP2,ZNF862,NPTX1,PDE1C,LRP12,MAPK7,TMEM231,ZCWPW1,KHDRBS2,SYBU,EPN2,CLSTN2,CDK20,VLDLR,ZBTB14" Drug 4413_DN Vitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "OGT,CDC14B,CBFA2T2,PLAA,QKI,CNTN1,NECTIN3,DBT,ERCC2,DENND4A,FGFR1,BAIAP2,IQCG,TRAF3IP2,USP19,KCNMB4,ATXN2L,TJAP1,IL6R,KCNN1,MMP16,MPP2,NF1,PLCD1,SLC25A23,LRP12,MAPK7,NKAIN1,ZFP30,SNCA,EXOC7,WSCD1,DMXL2,SZT2,KCNK12,ZNF45" Drug 3935_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADD2,C1QTNF1,TRMT9B,GAS7,PRX,CACNA1I,SEPT7,LY86,CNR1,DTNB,ELN,ERCC2,ANKMY1,REEP2,CAMKK2,CSDC2,GRM8,ITGA7,PCBP3,PDE4B,ENPP2,MTRF1L,NECAB2,SAMD9,PTPRB,PTX3,SH3BP2,ZNF334,MYH15,FAIM2,CDK19,ATP10B,CRTC1,PCDHA2,RIMBP2,UGT8" Drug 4809_UP Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "CDC42BPA,ARSE,MARK4,ALDH7A1,CRMP1,VCAN,RIMS2,SPOCK3,DMPK,EDIL3,EDNRA,EGFR,STX2,PIPOX,DCTN2,PCDH17,ATXN2L,HLF,MID1,NF1,NPTX1,PALM,MTRF1L,MAPK7,TCP11L1,FRMPD1,ZNF423,SYN2,TAL1,WSCD1,ZEB1,CRTC1,PCDHA5,CLIP2,SLC30A3,JPH3" Drug 310_DN "ICI 182,780; Down 200; 0.01uM; MCF7; HG-U133A" Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "MTUS1,ARHGDIG,ATP6V0A1,SYNJ2,CA12,CAMK2B,FOXN3,CNTFR,CNTN1,GREB1,C2CD2L,HS3ST2,MAMLD1,EGR3,ETV1,ZNF589,SUCO,PAXBP1,LSS,MAPT,AFF1,NOVA1,PRKAB2,PRKCB,MAPK3,FAM184A,SUSD4,RET,KBTBD4,SNAP25,DOK5,VPS13A,OBSL1,TNS1,WRN,ZNF142" Drug 5471_DN Allantoin [97-59-6]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ASPHD1,AK2,APBB2,SYNJ2,SCAPER,CNOT8,DCAF8,RCAN1,MRNIP,ENO2,ATP2C1,OGA,PRRC2B,ICA1,KHK,TM6SF1,OCRL,OXTR,SLC25A23,SMIM7,TMEM231,RNH1,FAM214B,ZNF430,SLC22A4,SMARCA4,LIMCH1,SPTAN1,CDK19,PHLDB1,IQCE,TRIM2,ZNF34,TK2,CABIN1,PLPPR2" Drug 4769_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "CDC42BPA,APC,ADGRB3,SYNJ2,CFAP410,RCBTB2,RAB28,VCAN,DCAF4,HDAC9,GIT2,FCF1,AASS,F5,FAM198B,DLC1,ZNF589,OLFM1,FHL1,TRAF3IP2,GNAL,HAS2,KCNH2,NEFM,NOVA1,PDE4B,LRRN3,ELOVL2,RASGRF1,RFX2,NLGN1,OGDHL,KDM4C,TNS1,LAT2,EPM2A" Drug 6620_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADGRF5,ZSCAN18,ATP6V0A1,ADAM23,ADGRB2,BMPR1B,NRXN3,AKAP6,MYRIP,ENTPD4,NCOR2,VCAN,PDE4DIP,PARD6A,EDN3,HIPK3,TNK2,NCALD,DLC1,FGF1,NSG1,OGA,CHL1,GCK,KITLG,ADAM22,PALM,PLXNB1,CCDC40,C1orf54,GAL3ST4,RGS3,HECW1,PCDHGA10,DOCK9,PIK3R5" Drug 3483_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "AK2,C1QTNF3,APOC1,CDK10,ARHGDIG,SLC4A4,ATP6V0A1,RIPK1,CFLAR,BAIAP3,CBFA2T2,PICK1,CSF1,MFAP3L,RUNDC3A,SPACA9,TJAP1,KCNH2,MIA2,ZNF862,GTDC1,RGS12,EMID1,KCNIP1,FAM214B,HECW1,PHLDB1,EXOC7,TRIO,VIPR2,ZNF24,REEP1,DNALI1,HPS4,ITM2C,TIGD6" Drug 6225_UP Butacaine [149-16-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ADCY6,AP2A2,SEMA6A,APC,PPFIA3,SLC4A4,ADAM23,ST3GAL5,CFAP410,B4GALT6,HOMER3,FAM149A,BAG4,GIT2,SPATA2,DMPK,RRAGB,BAIAP2,ZNF44,POLL,MBP,MID1,NPTX1,SLC11A2,SLC25A23,ZSCAN32,ACSM5,NKAIN1,RNASEL,GSTCD,KDM4C,ASTN2,TCF12,VIPR2,LAT2,MPPE1" Drug 5230_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "ABHD6,EPB41L5,SYNJ2,SCAPER,PLEKHB1,SLIT2,RAB28,FGFR1,PRELID3A,GFER,GPD2,TDRKH,STON1,PCLO,INPP5B,MAP4,NPR2,PRKAB2,MAPK7,PRPH,CEP97,ASAP3,SLC6A8,BTBD7,SLC22A4,MAPKBP1,ZHX3,CLSTN2,KANK1,EXOC7,TRIM2,CABIN1,TRIO,LMF1,GDPD5,SENP7" Drug 988_DN "estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "OSBPL1A,AK2,MARK4,CFLAR,SMARCAL1,CRY2,LRIG1,DZIP3,GPRASP1,SGSM2,DTNA,HIPK3,EIF5,ING4,SEMA4D,EFCAB2,FAM49B,CGREF1,SRCAP,MALT1,DIDO1,ATXN2L,LIG4,MBD1,MMP16,GIT1,CNOT4,OGG1,CCDC25,ANKRD6,DIP2A,LMF1,EVI5,HPS4,FIP1L1,AAAS" Drug 4966_UP Lysergol [602-85-7]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "NDRG2,TRMT9B,APBA2,APLP1,FAM131A,PRX,LDLRAD4,CBFA2T2,ARHGEF6,CSF1,PDE4DIP,MFAP3L,DMPK,ERCC2,RASL12,ZNF589,SEMA4D,SRCAP,POLL,IRF8,INPP5B,ITGA7,KCNJ5,AFF1,NNAT,RETREG1,NLE1,PPP5C,ZNF493,EMID1,DOP1A,ZBTB43,EXOC7,ZEB1,PCDHGB6,PIK3R5" Drug 7444_UP Azaguanine-8 [134-58-7]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.47E-03 1.00E+00 2.16E-02 2.44E-01 36 200 "CDK13,GYG2,SGCE,CFAP410,CA12,TBC1D5,DNM1,EIF5,MTSS1L,AGAP2,ZNF44,TMEM8B,SRCAP,GNG4,RASSF8,SMAD1,MAP4,MATK,ADAM22,NPTX1,OPRL1,PDE4B,CCDC40,ZDHHC14,RGS4,TCP11L1,RPS6KA2,SNCA,RBM34,ZHX3,PHLDB1,VPS13A,CDK20,ZFP37,TFIP11,SEMA3B" Drug CID000061671 vanadyl Stitch 3.48E-03 1.00E+00 2.17E-02 2.44E-01 51 307 "MTUS1,AGT,PDE8B,DNAH17,DYNLL1,ATP2B2,ALDH7A1,MTMR3,ENTPD2,LRBA,MAML1,DNAL1,DNAH9,EGFR,ERBB4,PTK2B,FGF1,FYN,BRD8,IGF1,KCNJ5,MBP,MYO7A,PCDH8,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ABCB1,PIK3C2A,PIK3R1,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTH1R,PTK2,PTPRG,MAPK12,SSTR2,CABIN1,VAV1,WRN,DNAH10" Drug ctd:C040929 bafilomycin A1 CTD 3.52E-03 1.00E+00 2.19E-02 2.47E-01 10 34 "ASIC1,AGT,APAF1,BID,MAPK3,LRRK2,SNCA,SIRT1,SLC30A3,SLC17A7" Drug CID000005279 NSC618487 Stitch 3.52E-03 1.00E+00 2.19E-02 2.47E-01 133 935 "CLK4,ADCY5,ADCY6,ADCY8,ADRA1B,AGT,MYH7B,APAF1,APBB2,MADD,ATP2A2,ATP2B2,BID,CFLAR,BTK,CACNA2D1,CALM1,CAMK2A,CAMK2B,CAMK2G,CAST,CCK,KRIT1,RGN,SCARB1,DGKI,LRBA,ZBED1,CDH2,TAOK2,MYL6B,SNCAIP,CSF1,CSNK1E,PLCXD3,MAML1,DGKB,DGKG,DAPK3,SLC12A6,EDN1,EDN3,EDNRA,EGFR,IRAK4,TNK2,EPHB1,ERBB4,PTK2B,FCGR3A,FDFT1,FER,FGF1,FGFR1,FGFR3,SYNCRIP,CAMKK2,ATP2C1,FYN,NEU3,MSTN,GHR,GRB10,PLCD4,GRIN2C,GRIN2D,GRM2,GRM8,GSN,MAP4K5,TNFAIP8L3,HSF2,MYLK2,IGF1,SCIN,IL6ST,ITGAM,JAK2,KCNJ5,KIT,STMN1,ASPRV1,MAPT,MATK,MBP,BLOC1S2,MYT1,NCF2,P2RY1,PDPK1,ABCB1,PIK3C2A,PIK3R1,PLCB2,PLCD1,MBOAT7,PPP2R2B,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,KLK6,PSMA6,PTK2,PTPN13,PCMTD2,BAALC,RPS6KA2,MAPK12,SMPD3,SLA,SIRT2,SLC12A4,SNAP25,SNCA,PEG10,STAU1,ADHFE1,NSFL1C,PLCB1,SYT1,TEK,ACTR6,CABIN1,BCL2L13,VGF,NDRG4,PLD4" Drug CID000126806 CASs Stitch 3.53E-03 1.00E+00 2.20E-02 2.47E-01 7 19 "AMH,LDHD,EXOG,SLC29A4,FDFT1,DICER1,TST" Drug CID000124009 AC1L3XQA Stitch 3.53E-03 1.00E+00 2.20E-02 2.47E-01 7 19 "ADCY5,ADCY6,ADCY8,ALDH7A1,CREM,PDE4B,PDE4D" Drug CID000055645 quinagolide Stitch 3.53E-03 1.00E+00 2.20E-02 2.47E-01 7 19 "GHR,IGF1,NOVA2,PRKCB,SST,SSTR1,SSTR2" Drug CID005288622 AC1NRBT8 Stitch 3.53E-03 1.00E+00 2.20E-02 2.47E-01 7 19 "AGT,APPL1,EDN1,EDNRA,FGF1,SEPHS1,AAAS" Drug CID000040032 Cloethocarb Stitch 3.57E-03 1.00E+00 2.22E-02 2.50E-01 12 45 "PRX,CBS,CDR1,TIGD7,CST3,FER,POLL,CLASRP,RET,TPM1,DPYSL5,EPM2A" Drug CID000010438 phorone Stitch 3.57E-03 1.00E+00 2.22E-02 2.50E-01 12 45 "CDO1,CTH,AASS,GGT7,GGT5,GPT2,NFE2L2,MAPK9,MAPK10,GSTCD,CLSTN2,ADHFE1" Drug CID005464109 I06-1821 Stitch 3.57E-03 1.00E+00 2.22E-02 2.50E-01 12 45 "AGT,CNR1,GAL3ST1,CYBB,GHR,IGF1,NPY,NPTX2,OXTR,SST,SSTR1,VGF" Drug CID000003104 AC1L1F6H Stitch 3.60E-03 1.00E+00 2.24E-02 2.52E-01 22 106 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,APC,ARHGDIA,CACNA1A,CACNA1B,CALM1,P2RX6,ENTPD2,LPAR4,MAP4K5,P2RY13,NPY,P2RX7,P2RY1,P2RY12" Drug CID000005056 "trans-3,4,5-trihydroxystilbene" Stitch 3.61E-03 1.00E+00 2.25E-02 2.53E-01 91 608 "APAF1,APOC1,APOC2,BCS1L,BID,CFLAR,CD86,FOXN3,PLEKHB1,CHRNA4,ABCG2,COX4I1,NCOR1,NCOR2,ABCG1,RIPOR2,LYPD1,GSDME,EDN1,EBI3,EGFR,TUBD1,ENO2,ERBB2,TUBB3,FGFR1,UBE2E3,FOXO3,FLT1,AK8,FYN,ZNF44,TUBA8,SESN1,PPARGC1A,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GUCY1A1,GUCY1B1,HBA1,TNFAIP8L3,IGF1,IL12A,ASPRV1,MAP4,MATK,MEF2C,MITF,NFE2L2,NFIX,NPR2,PDCD2,PIK3C2A,PIK3R1,PPARA,PPP3CA,PPP3CC,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PTK2,PTPRG,PTPRN2,RASGRF1,GSTCD,FBXW7,S100B,SAFB,MAPK12,MYO18A,SLA,SIRT2,APOM,SYT1,TAF9,TCF12,TNS2,SIRT1,CABIN1,TNS1,PIK3R5,TUBB1,TUBA1A,NETO1" Drug ctd:C084597 chlorcyclizine CTD 3.65E-03 1.00E+00 2.27E-02 2.55E-01 19 87 "SRPX,CAMK2G,HAPLN1,ABCG1,ELN,GABRB3,CPLX1,IL6ST,LSS,MAPT,MBP,TMOD2,ABCB1,PIK3R1,KHDRBS2,SMPD3,SMARCA4,CDH22,TST" Drug CID000006946 2-nitroaniline Stitch 3.65E-03 1.00E+00 2.27E-02 2.56E-01 27 139 "ACHE,APAF1,BCHE,BLM,CBS,CLTC,CNR1,NCOR1,HDAC9,DYNC1I1,ENO2,PPP1R1B,PPARGC1A,TCERG1,PACSIN2,HP,IGF1,OGG1,ABCB1,PKIA,QDPR,FBXW7,ATXN7,FOXRED1,SNCA,PRTFDC1,JPH3" Drug CID000000222 ammonia Stitch 3.67E-03 1.00E+00 2.28E-02 2.57E-01 78 509 "BRAP,AMPD2,AMPD3,AMT,DDO,NT5C3B,SLC4A4,BCHE,CACNA1B,CBS,KYAT1,CD86,CPS1,GDA,CRYM,CS,CSF1,PITPNM3,CTH,BOC,EARS2,CHRDL1,MED12,DTNB,TUBD1,ENO2,ERCC2,PIPOX,GMPR2,PTK2B,TUBB3,CHL1,MTHFD2,TUBA8,BRD8,GLUL,LOXL3,GPD1,STON1,GRIN2C,GRIN2D,CIT,PADI2,NEGR1,IDH3A,ITGAM,L1CAM,MAPT,MAT2A,NBL1,NCAM2,CNTN3,PKD1,PKM,PLEC,PRODH,RDX,S100B,SHMT2,SLC4A3,SLC14A1,SLC22A4,SP2,CLSTN2,SST,SYT1,PJA1,MLST8,THRA,ACTR6,KAT6B,NPL,TUBB2A,TUBB1,TUBA1A,SLC17A7,NELFE,GAN" Drug 995_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.68E-03 1.00E+00 2.29E-02 2.58E-01 32 173 "ALCAM,BIN1,SGCE,LRIG1,ARHGEF10,PDE4DIP,LYPD1,TOM1,CNNM1,EGFR,PDLIM5,GAD1,ERAP1,SRCAP,GNG4,GRB10,SLC2A6,TJAP1,MPP2,LYRM9,ZNF862,SETD4,SH3BP2,SYBU,ZBTB43,TSPYL2,CLSTN2,VPS13A,TRIM2,DOCK9,BEX4,CDK20" Drug 6451_UP Phenoxybenzamine hydrochloride [63-92-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.68E-03 1.00E+00 2.29E-02 2.58E-01 32 173 "BRAP,RGS20,N4BP2L1,RHBDL1,WHRN,CREM,DNAJB6,CDKL3,IP6K2,SESN1,RUNDC3A,GNAL,BTN2A1,IL6R,KCNJ5,MBD1,NOVA2,SMIM7,C1orf54,RASGRF1,TCP11L1,PPP4R3A,ZBTB43,TSPYL2,DDN,THSD1,JMJD6,BEX4,CLDND1,SLC30A3,KCNAB1,PLSCR4" Drug ctd:C045950 propiconazole CTD 3.70E-03 1.00E+00 2.30E-02 2.59E-01 224 1668 "NDRG2,FMNL2,ADCY6,ADD1,PLEKHH1,ADRA1B,KLHL13,ALCAM,BBOX1,EP400,APBB2,CDC14B,CDK10,MADD,ARRB1,DYNLL1,ATP2A2,ATP2B2,BID,PROM1,LDHD,ST3GAL5,CA8,CAMK2B,CARS,CBR1,CBS,RGN,SCARB1,ZNF445,MAGI1,FOXN3,CNOT8,PLAA,CLCN3,CLTB,NGEF,QKI,TMEM184B,HECTD1,TBPL1,AHCTF1,NSL1,NECTIN3,FAM171B,C2CD2,CREM,RBM39,CRY2,NCOR2,GDA,CSNK1E,GREB1,USP6NL,GAPVD1,DCAF8,LONRF1,TM9SF4,MAML1,IP6K1,DBT,ZC3H11A,DDX46,RHOBTB1,MTX3,FAM107B,CPEB2,RCAN1,ARRDC4,GOLT1B,OPTN,MBNL2,AASS,EIF4G2,PAN3,EIF1,PIPOX,ADGRV1,F5,SH3YL1,PTK2B,TAOK3,DLC1,RACK1,FDFT1,FGF1,FGFR3,SEC23B,VTI1B,FOXO3,UFM1,CAMKK2,CELF1,CSPG5,SARAF,INPP5K,CPLX1,GHR,PPARGC1A,RUNDC3A,RNPS1,TNRC6A,GLUL,GPT2,PRRC2B,DIDO1,GSTT2,FICD,PSIP1,MUM1,HBA1,PACSIN2,HLF,ELOVL5,HMGCR,HNMT,LRRC75A,IGF1,INPP5B,SLC35G1,TTYH2,STMN1,LIG4,HECTD2,SMAD1,PIK3AP1,GPR155,ADAM11,CHIC1,MKLN1,NRBP2,THYN1,NFIX,PAX6,PCDHGC3,PCSK5,PFKFB3,ABCB1,PIK3R1,SNX10,ZFYVE21,RETREG1,PLEC,PLTP,PLXNB1,PSAT1,RETREG2,SEPT4,PPARA,MINDY2,PPM1B,PPP3CA,RASGEF1B,CEP41,MAPK3,MASP1,RELN,BCAS3,PSMA6,ANKHD1,PTH1R,PTPRD,RIPOR1,SUSD4,RBBP8,RGS12,PBRM1,ZFHX4,CYB561D1,PCMTD2,FBXW7,ZC3H14,PTGR2,ST6GALNAC6,ATXN2,TNFRSF19,SMPD3,TRA2B,HSPA4L,SGK1,KIF16B,AMBRA1,SLC2A5,PEX26,CPEB4,ABTB1,SMARCA4,TMCC1,ZHX3,LHPP,PBLD,NXT2,NEK4,NSFL1C,PRRC2C,COBL,TACC1,ATMIN,ZEB1,PUM2,TNS2,SIK3,ENHO,NACC2,TK2,LRRC8A,TMPO,TNS1,TSC1,TST,TTC3,TUBB2A,BCL2L13,XPO1,SPHK2,MAP3K12,EVI5,RNF103,HPS4,ITM2C,PCBP4,RTN4,RNF170,SPATA13" Drug CID000072127 AC1L2HGV Stitch 3.72E-03 1.00E+00 2.31E-02 2.60E-01 9 29 "MCHR1,IGF1,MYCN,SST,SSTR1,SSTR2,SYP,SMUG1,VIPR2" Drug 2937_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.72E-03 1.00E+00 2.31E-02 2.60E-01 33 180 "ABHD6,ADORA1,AMPD3,BIN1,BCAS1,PDE8B,LDLRAD4,TAOK2,SULT4A1,RCAN1,PHC2,FAM13A,GSN,IRAK3,VSIG4,ITPKA,LYRM9,ZNF862,NF1,NLE1,SLC25A23,CEP41,GTDC1,IZUMO4,IQSEC2,LHPP,SAMSN1,SIN3B,CHST8,THRA,FLRT2,VIPR2,CLIP2" Drug 7356_UP Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.72E-03 1.00E+00 2.31E-02 2.60E-01 33 180 "APC,ARHGDIG,PDE8B,ST3GAL5,FAM189A2,PDE4DIP,FAM169A,EDNRA,EGFR,EIF4G2,ERCC2,EZH1,TPPP3,SRCAP,RASSF8,ATXN2L,HMGCR,HSF2,IL6R,LMO2,CNOT4,LRP12,ZSCAN32,C1orf54,KHDRBS2,ZNF821,SYBU,SNCA,TROVE2,TRIM2,RPGRIP1L,R3HDM1,CABIN1" Drug 2859_DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.72E-03 1.00E+00 2.31E-02 2.60E-01 33 180 "CDC42BPA,PPFIA3,EIF4G3,KRIT1,ZMYM4,CLOCK,FAM169A,ZFYVE16,TBC1D5,KIAA0586,FBXL5,LYPD1,IRAK4,FGFR3,OGA,GHR,MALT1,KIF2A,MAP4,ADAM22,STRN3,HSPA4L,PPP4R3A,UHRF1BP1L,ERBIN,VPS13A,TACC1,ANKRD12,FAM208A,ACTR6,UBE3A,PHTF2,IFT88" Drug 5420_UP Hexetidine [141-94-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-03 1.00E+00 2.32E-02 2.62E-01 34 187 "NDRG2,ADD2,C1QTNF1,ADGRF5,AMPD3,APBA2,GAS7,CDC14B,ADAM23,GYG2,BAIAP3,FAM189A2,CPS1,NCOR2,ARHGEF10,RIPOR2,MYEF2,AASS,C3orf18,MTSS1L,AGAP2,SRCAP,GDF9,GUCY1B1,NF1,ACSM5,ZSCAN2,RGS4,RGS12,SLA,ZNF423,CDK19,TACR1,XRCC4" Drug 4589_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-03 1.00E+00 2.32E-02 2.62E-01 34 187 "ADRB2,LTBP4,ALK,SLC4A4,BAIAP3,CAMK2B,CAPN3,RAB28,QKI,CREM,PDE4DIP,BRINP1,EDN1,NRN1,AMOTL2,PDLIM5,ALDH1L1,KCNF1,SMAD1,MAPT,AFDN,OXTR,PALM,PDE4D,PFKFB4,PTPRH,PTX3,RGS12,FBXW7,SEC14L1,TRIO,RUNDC3B,WNT7A,NAV3" Drug 3240_UP GBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-03 1.00E+00 2.32E-02 2.62E-01 34 187 "SPARCL1,SEMA6A,SLC16A4,CD86,WHRN,NRG2,VCAN,RIMS2,EDN1,EGR3,CDKL3,FAM198B,FGFR1,HPCAL4,PRELID3A,ZNF44,SIGLEC8,ALDH1L1,GCNT2,GPR162,ADAMTS13,KPNA5,MAP2,NF1,NTRK2,ENPP2,LRP12,KHDRBS2,KCTD17,SLC22A4,ARC,DMXL2,FAM155A,MKRN3" Drug 5204_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-03 1.00E+00 2.32E-02 2.62E-01 34 187 "TRMT9B,AMH,AMT,SLC2A11,CFLAR,HAP1,KRIT1,TBC1D5,MBNL2,ING4,TNK2,EZH1,REEP2,FAM198B,FHL1,EFCAB2,SRCAP,GLYR1,MSL3,GPER1,CNTRL,AP4S1,ADAM22,ZNF862,NELL2,CNOT4,PLEC,ZNF493,DOK5,SS18,RGL1,XRCC4,MPPE1,MARCH8" Drug CID000498506 dihydroxy(oxo)azanium Stitch 3.77E-03 1.00E+00 2.32E-02 2.62E-01 8 24 "DDR1,CLDN10,GPT2,NBL1,OPA1,SMOX,PPP1R1A,TK2" Drug CID000001328 DEPX Stitch 3.77E-03 1.00E+00 2.32E-02 2.62E-01 8 24 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ALDH7A1,RNH1,SST" Drug CID000000587 phosphocreatine disodium Stitch 3.77E-03 1.00E+00 2.32E-02 2.62E-01 25 126 "BRAP,AK2,AMPD2,AMPD3,MADD,ATP2A2,ATP2B2,ALDH7A1,CFLAR,LDHD,ENTPD2,CS,AK8,ATP2C1,GATM,GCK,OPA1,P2RY1,PIK3C2A,PKM,SLC6A8,IFT122,P2RY12,SLC30A4,GJC2" Drug 6243_DN Retinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ASPHD1,CLK4,STX16,MPDZ,C5,CNOT8,ARHGEF10,DZIP3,APPL1,GREB1,PPP6R2,FBXL5,PARD6A,SGSM2,NR1D2,EGR3,ARMCX1,OLFM1,TRAF3IP2,MALT1,JAK2,NEK1,PIK3R1,KCTD15,PPP3CC,PKIA,ZNF430,ELMO2,COBL,TACC1,DNMBP,SATB2,TRPS1,SSBP2,LMF1" Drug 1949_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; PC3; HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "APBB2,GAS7,STX16,GYG2,CA12,KRIT1,CTH,HDAC9,ZNF804A,DTNA,YAF2,ACSL4,RACK1,FGFR1,PDLIM5,TMEM8B,ARFIP1,CRCP,TJAP1,MPP2,NFYA,CNOT4,NOVA1,NTRK3,PLCD1,TCP11L1,ATXN2,ST6GAL1,SLC11A1,CDK19,EXOC7,PDLIM2,TCF4,NSD1,LAT2" Drug 6072_DN Etanidazole [22668-01-5]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "AP2A2,FAM131A,MARK4,ATP6V0A1,CACNA1I,CFAP410,ARHGEF2,RCHY1,NECTIN3,SIPA1L1,RIMS2,DTNA,EDNRA,C3orf18,CGREF1,DISC1,SEPT9,INPP5K,POLL,INPP1,MID1,NF1,PTK2,RIPOR1,ZDHHC14,SEC14L1,FAM214B,SNCA,IQSEC2,TSPYL2,PHLDB1,SYN2,PCDHA5,SLC44A1,ZNF45" Drug 2793_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "CA4,USP2,ARMC8,CSF1,CSF1R,SPOCK2,FAM198B,ZNF589,FGFR1,SEMA4D,ELOVL5,HNMT,LMO2,SMAD1,MIA2,MX1,NEK1,NF1,SLC11A2,NTRK2,NLE1,LRP12,PPP2R2B,CEP41,PRKAR1B,DCUN1D2,SH3BP2,SIRT2,LIMCH1,CEP68,SYNE1,SLC44A1,TPM1,VGF,KCNK12" Drug 828_UP 5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "TRMT9B,EP400,APLP1,SYNJ2,LDLRAD4,STOML1,SGSM2,CDON,CELSR3,AASS,HSD17B14,RASGRP2,ANKMY1,ST3GAL6,BAIAP2,FYB1,SRCAP,LPAR4,GPR37,RASSF8,KCNH2,AFF1,MSR1,POLG,PTPRB,ZNF821,NLGN1,BTBD7,ZKSCAN3,SNCA,SPTAN1,PLCB1,IQCE,CRTC1,TK2" Drug 2844_UP Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "FZD9,BIN1,SEMA4G,N4BP2L1,ADAM23,CFLAR,PROM1,CACNA1I,CA4,RCBTB2,TPP1,C3orf18,VPS13B,NCALD,FGF12,FAM49B,DISC1,SEPT9,KHK,MID1,AFF1,ADAM22,PCDH9,NECAB2,MAPK10,RGS12,RASA3,PEX26,SLC9A5,SNCA,KDM4B,IQSEC2,ZEB1,ZKSCAN5,REEP1" Drug 6070_DN Benzethonium chloride [121-54-0]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "PPFIA3,ATP6V0A1,CFLAR,MTMR3,CA12,NFS1,SOCS6,TAOK2,PLAA,RIMS2,MAML1,DAPK3,TMCC2,DTNA,SUGP2,MRNIP,STX2,DLC1,FGF12,FGFR3,SEMA4D,ITPKB,PDE4B,NLE1,PPP3CC,PRKAR1B,MAPK7,ZDHHC14,SNCA,KDM4C,TACC1,KIAA0930,NACC2,CABIN1,REEP1" Drug 3855_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NDRG2,ADD2,APAF1,PRX,PLA2G4C,STX16,WHRN,CRY2,NCOR2,SNCAIP,DAPK3,NR1D2,AGAP2,FUT9,SRCAP,SPIN1,STON1,GPER1,GSN,HLF,IL6ST,LSS,KITLG,AFDN,MMP16,ADAM22,NEK1,PCDHGC3,PCDH9,GRAMD1C,RGS12,ZBTB43,DOCK9,RUNDC3B,SENP7" Drug 5355_UP Lynestrenol [52-76-6]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "APBB2,CFLAR,ST3GAL5,KALRN,SLIT2,SIPA1L1,EGFR,EGR3,ERCC2,SRCAP,GLYR1,GNG4,ATXN2L,JAK2,IPO5,MAP4,MIA2,NPTX1,PDE4B,SMOX,CNNM2,TMEM104,KCNIP1,SH3BP2,SYBU,SLC9A5,LIMCH1,TSNAXIP1,TRIM2,ZNF34,TRPM2,LAT2,XRCC4,NDRG4,SEMA3B" Drug 5216_DN "radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ABHD6,CDC42BPA,APC,HIP1R,BAG4,PDE4DIP,DNM1,RRAGB,KAT8,ZNF589,POMT1,PDLIM5,SEPT9,AHDC1,PCLO,INPP5B,ITPKB,LSS,NFYA,NPR2,MBOAT7,CNNM2,RIPOR1,TMEM231,SYBU,KBTBD4,CDK19,LHPP,TROVE2,THSD1,SATB2,TNS2,VAV1,UBE3B,PHTF2" Drug 4154_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NDRG2,C1QTNF3,AMT,ALDH7A1,CA12,HAP1,CBFA2T2,CACNA2D2,FOXN3,RAB28,ZNF337,DBN1,HIPK3,PLXNC1,ZNF589,PRELID3A,KHDRBS3,SEPT9,SRCAP,HNMT,TJAP1,KCNQ3,KITLG,CNOT4,SLC11A2,SH3BP2,FNDC3A,SNCA,TBCEL,CRTC1,PARD3,ZKSCAN5,VGF,WIPF1,CLDND1" Drug 3684_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "SYN3,NDRG2,ADCY6,ADD2,FAM135A,GAS7,PPP4R4,DNAH17,ATP1A3,SLC4A4,CHRNA4,NRXN3,VAX2,FCF1,DLC1,ANKFY1,GRIK5,NXPH3,ATXN2L,MMP16,NNAT,CLDN11,MINDY2,PTPRB,CCDC40,RGS4,CSRNP3,FBXO11,SOX15,PCDHGA10,CRTC1,HIRA,UCHL1,SPHK2,EMSY" Drug 1211_DN retinoic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ABR,APBA2,BCL7A,WHRN,PDE4DIP,CNTNAP2,SNPH,HDAC4,B3GAT3,SEZ6L2,EIF5,ERCC2,FGF1,GAD1,GFER,PRRC2B,INPP5B,L1CAM,MAP4,NDP,NFIX,NPR2,SETD4,PDE4B,BCAS3,RIPOR1,ASAP3,ZBTB43,TROVE2,THSD1,TBL1X,TIMP4,TSC2,NPDC1,MAP3K12" Drug 3795_DN alpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "MTUS1,CDK13,STX16,ATP2A2,ADAM15,SYNJ2,PLEKHB1,PLAA,TPP1,CNTNAP2,PHF14,EDIL3,HIPK3,EGFR,MBNL2,CDKL3,FGF1,GPD2,TJAP1,LSS,NFYA,STRN3,MINDY2,MAPK7,RPS20,FNDC3A,DZIP1,ZNF415,ZHX3,THSD1,NXT2,FBXW11,TMPO,TNS1,REEP1" Drug 1783_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ADORA1,EIF4G3,BCL7A,CA12,HAP1,SLIT2,PPP6R2,SPOCK2,C2CD2L,RASGRP2,FCGRT,BAIAP2,ALDH1L1,LILRA2,VSIG4,ITGAM,LAMA2,MAP4,GIT1,MX1,MYO7A,NELL2,OGG1,PALM,ELOVL2,RGS12,RNASE1,SMARCA4,KDM4B,STX1A,KIAA0930,ICAM5,TNS1,TRPM2,URM1" Drug 2430_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ABHD6,AK2,PKP4,APAF1,APBB2,APC,SLC4A4,C5,MYRF,LDLRAD4,CACNA1A,TMEM184B,ENTPD4,VCAN,DOCK4,SPATA2,TUBD1,FGFR1,ALDH1L1,SRCAP,AHDC1,CRCP,ITGAM,MAP4,CNOT4,MBOAT7,ZNF493,SMARCD3,TSPYL2,RBM26,TROVE2,EXOC7,THRA,MAP3K12,GDPD5" Drug 6223_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ALCAM,SRPX,AMH,PLA2G4C,USP2,CACNA2D2,CHN2,CSF1R,MFAP3L,C2CD2L,DMPK,CNNM1,MBNL2,ING4,IL6R,MAP4,PTOV1,NTRK2,PALM,PPP2R2B,PRKAR1B,NKAIN1,NEK11,SLC11A1,IQSEC2,ARC,MCF2L,GPR161,UBTF,LAT2,UPF3A,MAP3K12,GDPD5,KAT6A,TIGD6" Drug 1233_DN rosiglitazone; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "SHROOM2,BCHE,ST3GAL5,IL33,LHX2,RAB28,WHRN,ABI3BP,CREM,PDE4DIP,SNPH,TMCC2,RGS17,EZH1,POMT1,AHDC1,GLYR1,GPR37,SYNPO,PCDH9,GRAMD1C,TRIM68,ZFHX4,MAPK12,CSRNP3,FAM102A,ZKSCAN3,PDZD2,SPATA7,TTBK2,KIAA1107,PARD3,SSBP2,EPM2A,SENP7" Drug CID006426631 Rp-cAMPS Stitch 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,ALDH7A1,CACNA2D1,CALM1,KRIT1,LRBA,CALCRL,CRCP,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,GUCY1B1,IGF1,KCNJ5,KCNK3,NPR2,OXTR,PDCD2,PDE3A,PRKACB,PKIA,PRKCB,MAPK3,PTH1R,ACTR6,VIPR2" Drug 5932_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ASPHD1,ADRA1D,AMPH,BIN1,GAS7,CDK10,NRP2,CLTB,PDE4DIP,PLPPR4,CHRDL1,TOM1,CNNM1,SUGP2,AASS,GNG4,SCIN,AFDN,MSR1,PFKFB2,PIK3R1,CCSER2,SLA,KDM4B,ARHGAP26,TROVE2,JMJD6,ASTN2,R3HDM1,CABIN1,TNS1,PDIA2,PLPPR2,NAV3,SLC17A7" Drug 3213_UP Colchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NME5,ALDH7A1,CALB2,RASSF2,ARMCX2,DMPK,DTNA,PLXNC1,SPEG,ETV1,FGFR1,PRELID3A,HAS2,IRF8,KCNN1,LSS,AFDN,GIT1,NF1,PALM,PCSK5,PFKFB2,RGS12,KCTD17,SEMA6D,SCN2B,ASAP3,SLC2A5,PEX26,LIMS2,SLC6A8,GPR161,TLR4,R3HDM1,VSNL1" Drug 6613_DN Theobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "DNAH17,MYRF,CFAP410,CACNA1A,SCARB1,PLEKHB1,PICK1,CPS1,CREM,ABCG1,CSF1R,EGFR,HSD17B14,ANKMY1,FYN,TRAF3IP2,INPP5K,CRCP,GPD2,SPACA9,HLF,MBD1,AFDN,MMP16,CNOT4,PRKAR1B,PTPRE,RPS6KA2,SH3BP2,SLC14A1,RPGRIP1L,CRTC1,ZNF711,KAT6A,PHTF2" Drug 4305_DN Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "AK2,SCAPER,SRSF11,RAB26,HOMER3,ENTPD4,GIT2,CNNM1,STX2,SPIN1,GPR37,RASSF8,AGFG1,IL6ST,KHK,MAP4,MMP16,MX1,NFIX,NLE1,STRN3,PRKAB2,SAMD9,TMEM231,SEC14L1,KBTBD4,ZBTB43,TTBK2,PLCB1,TBL1X,TCF4,DICER1,TMPO,R3HDM1,ZNF24" Drug 952_DN carbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "CLK4,OGT,ATP6V0A1,BARD1,RAB29,KRIT1,RAB28,HOMER3,DCAF8,GIT2,DBT,EGR3,PCOLCE2,EPB41L2,EZH1,SCML2,ANKFY1,EFCAB2,GALC,SPIN1,GPER1,HSF2,CNOT4,NRCAM,ING3,PTK2,TTC13,PPP4R3A,UHRF1BP1L,NXT2,ANKRD12,DICER1,AP4E1,TMPO,LMF1" Drug 2068_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "MTUS1,CDC42BPA,ARNTL,CDK13,STX16,MTMR2,SPAG9,CDH2,CLTB,QKI,BAG4,CREM,GIT2,HIPK3,FCF1,EGFR,MBNL2,ING4,DENND4A,EZH1,FHL1,SIGLEC8,GCNT2,MAP4,MEF2C,ZFYVE21,PPP5C,RAD51D,SS18,TBCEL,ZKSCAN5,UBE2H,UGT8,MAP3K12,SENP7" Drug 862_UP 5230742; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "DOC2A,EP400,PPFIA3,AKAP6,TBC1D5,AASS,STRADA,FHL1,FAM49B,ZNF44,CACFD1,GRM8,MAP4K5,INPP5B,PACRG,MBD1,NNAT,RETREG1,PRKAR1B,SAMD9,ZSCAN32,ZSCAN2,FNDC3A,FAM214B,BTBD7,TTC17,ZBTB43,THSD1,PLCB1,CRTC1,AP4E1,LMF1,REEP1,NT5M,EVI5" Drug 4149_DN Dibucaine [85-79-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ASIC1,NDRG2,NME5,AMPD3,PLA2G4C,SYNJ1,FOXN3,CRMP1,CRY2,DCAF4,GPRASP1,DCAF8,TMCC2,HIPK3,ING4,SCML2,PRELID3A,SEPT9,GPER1,ATXN2L,DHX35,KCNH2,KIT,CDK18,MINDY2,KCNIP1,PEX26,ZBTB43,TROVE2,THSD1,PLCB1,EXOC7,SIN3B,KCNAB1,KAT6A" Drug 4001_DN Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ASIC1,BIN1,ARRB2,KIF1A,RAB26,HOMER3,SH2B1,ARHGAP24,RUSC2,DTNA,PLXNC1,COQ7,SCARA3,CINP,B4GALNT1,SEPT9,GCNT2,GFER,MSL3,POLL,SHISAL1,MN1,FA2H,CNNM2,PEX26,TSNAXIP1,SS18,ARC,TK2,CABIN1,WIPF1,XRCC4,REEP1,SEMA3B,MPPE1" Drug 2427_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ASIC1,PPFIA4,APAF1,APOC1,ADAM23,SCAPER,HIP1R,PLAA,QKI,CRY2,GSDME,SGSM2,DTNA,CNNM1,FHL1,AGAP2,IQCG,GATM,NCKAP1L,DHX35,MAP4,NF1,NINJ2,PDE4D,CNNM2,ZNF671,ZNF821,FAM214B,SLC6A8,CCDC88A,ADGRL3,CHST8,ICAM5,TRPS1,REEP1" Drug 5914_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "AP2A2,OSBPL1A,AMPD3,APOC1,MARK4,ATP6V0A1,TPP1,QKI,NECTIN3,RIMS2,SEC14L5,RASSF2,DTNB,MBNL2,ING4,DIDO1,KCNN1,MX1,MBOAT7,MAPK7,HSPA4L,SH3BGR,PPM1E,CPEB3,PREX2,ZKSCAN3,SPTB,RGL1,TBCEL,ZEB1,TNS1,FLRT2,VGF,LAT2,SLC17A7" Drug 4317_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NME5,ALK,EP400,ADGRB2,CFLAR,CFAP410,CACNA2D2,FOXN3,CNTN1,CPS1,CRY2,CSNK1E,PDE4DIP,DCAF4,ING4,FGF1,CINP,OGA,GNG4,IL6ST,NDP,CNOT4,PDE4D,NLE1,C1orf54,ASAP3,PREX2,ZBTB43,ELOVL4,R3HDM1,TPM2,VIPR2,NPDC1,KCNAB1,MPPE1" Drug 607_UP butein; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "BRAP,LTBP4,BIN1,SLC4A4,CCNT1,CBFA2T2,FAM13A,EGR3,CDKL3,SEPT9,BRD8,HPGDS,GRIK5,GRIN2C,GRM2,PADI2,KIFC3,MAPT,MBP,MITF,NFIX,NNAT,PDE1C,RIPOR1,CCDC40,C1orf54,CXXC4,SPART,PRRC2C,ANKRD12,AGTPBP1,HIF3A,ZNF23,MAP3K12,GJC2" Drug 2293_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "LTBP4,APOC1,CDK10,MARK4,SYNJ2,GYG2,SPAG9,CNOT8,CSNK1E,DTNA,FCF1,SUGP2,EPB41L2,VPS26C,ARFIP1,ACOT7,ITPKB,MBNL1,NFYA,CNOT4,SLC11A2,PLEC,PRKAR1B,SAFB,ZNF821,FUZ,BTBD7,MAPKBP1,CLASP2,SS18,NXT2,PLCB1,BHLHB9,ZBTB14,SMIM8" Drug 7065_UP SC 19220; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "APAF1,APC,PPFIA3,STX16,SLC25A14,CPS1,VCAN,DZIP3,DAPK3,RUSC2,PARD6A,RCAN1,EGFR,ING4,SCML2,DLL3,FYB1,TRAF3IP2,SLC2A6,MIA2,SCAMP5,TAGLN3,PIK3R1,PPP5C,PRKAR1B,MAPK7,ZSCAN32,TCP11L1,SNCA,ZNF415,SS18,JMJD6,TRIO,WNT7A,PHTF2" Drug 1935_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; PC3; HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "APLP1,APOC1,CACNA1I,CBR1,KRIT1,CDH2,ARHGEF10,SNPH,ZNF337,RUSC2,EIF1,GAD1,INPP5K,MALT1,TDRKH,PACSIN2,NELL2,PCDH9,ZNF426,FSD1,DPF2,PEX26,ZKSCAN3,LIMCH1,FNBP1,MMS19,PJA1,EXOC7,TBL1X,WSCD1,GPR161,CBX5,PLPPR2,ZNF142,GDPD5" Drug 2637_DN Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ADD1,EPB41L5,KIF1A,CFLAR,CFAP410,SCARB1,SIPA1L1,PUM1,ARHGAP32,GIT2,LYPD1,IRAK4,FER,FGFR1,AGAP2,ERAP1,MSL3,IL6ST,IPO5,MAP4,LYRM9,PTPN13,RIPOR1,SLC25A36,ZNF821,EPN2,ELMO2,MAPKBP1,ZHX3,SS18,ZNF34,TK2,FIP1L1,MPPE1,RNF146" Drug 6385_UP 5707885; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "PLA2G4C,ATP6V0A1,ADAM15,ARHGAP33,RAB28,ARHGEF6,MFAP3L,RCAN1,C3orf18,RCAN2,VPS26C,ZNF589,FGF12,GATM,SRCAP,GLYR1,GNG4,GPD2,ICA1,INPP5B,LSS,KITLG,PLEC,C19orf57,PRKCB,PTPRO,PPM1E,IZUMO4,ZC3H13,SZT2,PCDHGA10,PCDHA5,TRO,VLDLR,UBE3B" Drug 5091_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ACTN1,ADRB2,PPFIA4,GAS7,APLP1,CBS,NRXN3,ABCG1,CNTNAP2,SGSM2,PDLIM5,GAD1,ICA1,MAP4,NF1,CNOT4,MINDY2,PPP5C,SNRK,PTPRH,TMEM231,RPS6KA2,SEC14L1,DZIP1,SLC4A3,SPTB,ZBTB43,DDN,PHLDB1,PDLIM2,TPM2,TRIO,LAT2,NAV3,FAM13C" Drug 5914_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "TRMT9B,APBB2,APC,SEMA4G,PLA2G4C,MARK4,KSR1,CACNA1I,CD86,LHX2,STOML1,CSNK1E,EGR3,IGSF6,RRAGB,FER,ICA1,IL6R,KHK,MID1,PALM,RET,RGS3,TCP11L1,SLC4A3,SLC2A5,EPN2,ARHGEF40,SLC11A1,CEP68,IQCE,TNS2,TNS1,CDK20,SPHK2" Drug 2739_DN Iopromide [73334-07-3]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "MTUS1,APAF1,FAM131A,PPP4R4,HIP1R,CREM,CSF1,USP6NL,KIAA0753,E2F5,HIPK3,RRAGB,KAT8,PDLIM5,LILRA2,DIDO1,PADI2,ATXN2L,ELOVL5,MAP4,NNAT,CNOT4,PLTP,POLG,TMEM231,CEP97,TCP11L1,ZNF821,PREX2,SMARCD3,TMCC1,STX1A,FLRT2,CLIP2,ZNF225" Drug 7409_DN Indomethacin [53-86-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "BRAP,NCOA1,STX16,TAOK2,RAB26,GREB1,GPRASP1,KIAA0586,PARD6A,DNM1,DPH1,SUGP2,KAT8,FAM49B,AHDC1,GPD2,MAP4,NACA,NF1,PLXNB1,MINDY2,PRKAB2,PRKAR1B,QDPR,GTDC1,CLIP1,TRAPPC13,SEC14L1,SGK1,EPN2,PDZRN3,ZBTB43,LHPP,CEP68,ZBTB14" Drug 3570_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "AK2,AMPD3,ARRB1,PDE8B,MARK4,HIP1R,SOCS6,ABI3BP,PDE4DIP,GIT2,DTNA,SUGP2,USP19,COPS8,HNMT,ICA1,LIG4,MAPT,ADAM22,NF1,NRCAM,MBOAT7,PTPRE,EMID1,SH3BP2,NLGN1,SLC6A8,BTBD7,SPART,ARHGEF9,SIK3,CABIN1,SMUG1,RUNDC3B,ZBTB14" Drug 1341_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NDRG2,APBB2,STX16,BACH1,SCAPER,SCARB1,DBT,DTNA,FCF1,EIF5,PTK2B,FHL1,DISC1,GLYR1,MSL3,POLL,KIF2A,NF1,OGG1,CCSER2,POU6F1,DPF2,DCUN1D2,SUPT20H,TMCC1,DOP1A,IZUMO4,SS18,EXOC7,ZEB1,TRPS1,ZNF32,URM1,UBE3B,NLRP3" Drug 1670_DN Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "EP400,RIPK1,MPDZ,MTMR2,ZMYM4,SRSF11,SMARCAL1,DCAF8,KIAA0586,C2CD2L,DMPK,VPS26C,ARMCX1,FAM49B,INPP5K,FERMT2,RNFT2,MEIS1,RETREG1,NUBPL,EPN2,CDK5RAP2,KDM4B,SPTAN1,CDK19,SS18,KANK1,TACC1,EXOC7,TRIM2,DOCK9,TP53BP1,METTL3,SEMA3B,MPPE1" Drug 6623_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ALK,ATP6V0A1,SYNJ1,SCAPER,CNR1,SEC14L5,EDIL3,ELN,FGF1,PRELID3A,GFER,ICA1,ITPKA,LAMA2,MATN3,ADAM22,NF1,PCDH9,DUSP26,CNNM2,PTN,C1orf54,RGS4,SH3BP2,ASAP3,SLC2A5,ZNF334,SPTB,CDK19,PHLDB1,COBL,ZNF34,ICAM5,ZNF24,ZNF74" Drug 505_UP 17-AAG; Up 200; 1uM; SKMEL5; HG-U133A Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "NDRG2,OSBPL1A,AMT,APBB2,BID,CALB2,SH2B1,PDE4DIP,RCAN1,MBNL2,ERCC2,BAIAP2,SEC23B,CINP,ZNF44,NEU3,ADAMTS6,PADI2,IDH3A,KCNH2,NACA,NPY,SETD4,PALM,CEP41,PRKAR1B,KLK6,GSTCD,STK32B,HSPA4L,PPM1E,SLC12A4,CDK19,LMO3,TRIM9" Drug 5289_DN Flucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "ADCY6,ZBTB10,NUMB,SLC4A4,ADAM15,BCL7A,CFLAR,SYNJ1,MTMR2,CREM,SH2B1,USP6NL,PHC2,PCOLCE2,INPP5K,ZNF276,TCERG1,GRB10,HSF2,INPP5B,MAN2A2,MAPT,PTOV1,PLEC,MINDY2,PRKACB,ELMO2,ZBTB43,SS18,MTCL1,TRIM2,NSD1,PARD3,WBP2,HIRA" Drug 1924_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HG-U133A Broad Institute CMAP Down 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "C1QTNF1,MAP4K3,WASF1,ARHGEF2,QKI,CDC42BPB,RNF14,APPL1,MATR3,ETV1,ST3GAL6,FGFR1,UFM1,CAMKK2,HTATSF1,MAP4K5,KTN1,MARK3,SCAMP5,CCSER2,GPSM2,STRN3,PTK2,C1orf109,CCDC25,FNDC3A,FAM214B,FNBP1,PEG10,CLASP2,LARP4,STAU1,DMXL2,DOCK9,ZNF195" Drug 4795_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.77E-03 1.00E+00 2.32E-02 2.62E-01 35 194 "KIAA1324,AMPD3,CDC42BPA,CDK13,MARK4,BAIAP3,CBFA2T2,AATK,CSF1,SPOCK2,FAM13A,TNK2,F5,AGAP2,GNG4,GRB10,SYNPO,MBD1,ADAM22,MX1,NF1,NTRK3,P2RY1,NLE1,PTPRE,C1orf54,LIMS2,SMARCD3,IZUMO4,SAMSN1,SYN2,GPR161,BEX4,WIPF1,ZNF74" Drug ctd:D016912 Levonorgestrel CTD 3.77E-03 1.00E+00 2.32E-02 2.62E-01 38 215 "AGT,ADGRF5,PKP4,AZGP1,PTBP2,CD86,DLGAP2,AHCTF1,CDC42BPB,GREB1,MRO,TMEM35A,F5,F8,NSG1,SARAF,GABRG2,RAPGEF6,GLYR1,ZNF638,FERMT2,ELOVL5,IGF1,MBNL1,PDE1C,TMOD2,ABCB1,PPP2R2C,CPEB3,SLC2A5,BTBD3,SNRPN,FNBP1,DOK5,KLHL4,NACC2,CSMD1,DOCK8" Drug CID000325714 NSC294864 Stitch 3.87E-03 1.00E+00 2.38E-02 2.69E-01 17 75 "FZD9,ATP1A1,ATP1A3,ATP1B3,CACNA2D1,GAL3ST1,VCAN,GREB1,GTF2IRD2,CSPG5,HAS2,TTYH2,NCF2,TACR1,DNMBP,CYB561A3,CLIP2" Drug CID000162602 dopamine quinone Stitch 3.93E-03 1.00E+00 2.42E-02 2.73E-01 16 69 "EPS15L1,DNM1L,GAD1,GPR37,PACRG,MAPT,OPA1,MAPK9,MAPK10,RELN,FBXW7,LRRK2,SIRT2,SNCA,UBC,UCHL1" Drug CID005310993 acipimox Stitch 3.93E-03 1.00E+00 2.42E-02 2.73E-01 16 69 "APOC1,APOC2,SCARB1,LRBA,FDFT1,PPARGC1A,HBA1,IGF1,GPR85,PLTP,PRKACB,SST,APOM,THRA,SMUG1,NETO1" Drug CID000448864 hexadecyl octanoate Stitch 3.95E-03 1.00E+00 2.43E-02 2.74E-01 15 63 "CBS,KRIT1,CRLF1,TBC1D5,DBN1,KCNK3,CAMK2N2,MEST,KITLG,PLEC,PPP3CA,SLC12A2,SYP,TSC1,TSC2" Drug CID000006569 methyl ethyl ketone Stitch 3.98E-03 1.00E+00 2.45E-02 2.76E-01 88 587 "KCNH8,AGT,CDK10,CDK13,KSR1,LRBA,CDH2,ZNF445,TAOK2,CSF1,CSF1R,HDAC9,B3GAT3,EDN1,EGFR,RASGRP2,EPHB1,ERBB2,ERBB4,RPS6KC1,PTK2B,TUBB3,FGF1,FGFR1,FGFR3,FOXO3,FLT1,FYN,GPR12,GRB10,TNFAIP8L3,BACH2,MYLK2,IGF1,IL6ST,ITGAM,JAK2,KCND2,MAP2,MARK1,MARK3,MATK,MBP,KITLG,MITF,MYT1,NF1,NFE2L2,NTRK2,CNTN3,PCSK5,PIK3R1,PLIN1,PPARA,PPP3CC,PPP5C,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,MASP1,LAMA1,PTK2,RET,PCMTD2,RPS6KA2,MAPK12,MRAS,FNDC3A,SLA,CDK19,CLSTN2,ADHFE1,SYT1,AKTIP,ACTR6,CABIN1,CDK20,RUSC1,UBTF,GORASP1,VLDLR,SPHK2,FTSJ1,MAP3K12" Drug CID000003891 AC1L1GXW Stitch 3.98E-03 1.00E+00 2.45E-02 2.76E-01 20 94 "MYH7B,NUMB,SEPT7,MAGI1,DLGAP1,NUMBL,CLTC,DBN1,SHANK1,DNM1L,F8,FHL1,SYT3,ATE1,SYNPO,SCIN,MYO5A,PDLIM2,ACTR6,SYNPO2" Drug 6187_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.99E-03 1.00E+00 2.45E-02 2.76E-01 31 167 "BIN1,DDO,CFLAR,TPP1,CREM,CSNK1E,PDE4DIP,OPTN,FAM13A,MBNL2,ETV1,FECH,FGFR1,BAIAP2,OGA,MSL3,MUM1,NRCAM,PDE4B,PDE4D,MBOAT7,PRKACB,CNNM2,PTPRN2,HSPA4L,CPEB3,SNCA,SPTAN1,CDK19,FLRT2,ZBTB38" Drug CID004393961 "1,1'-Carbonyl-di-(1,2,4-triazole)" Stitch 4.01E-03 1.00E+00 2.47E-02 2.78E-01 11 40 "NCOA1,SUMF2,GGT7,GGT5,GPT2,ENPP2,PSMA6,SHMT2,ST6GAL1,TSC1,TSC2" Drug CID000008064 "1,4-butanediol" Stitch 4.01E-03 1.00E+00 2.47E-02 2.78E-01 11 40 "ABHD6,SCARB1,NPIPA1,BOC,E2F5,NELFCD,RNASEL,SP4,ADHFE1,MLST8,TK2" Drug CID000003758 IBMX Stitch 4.01E-03 1.00E+00 2.47E-02 2.78E-01 59 368 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,APOC2,ARSE,PDE8B,ALDH7A1,RIPK1,HCN2,CACNA2D1,CALM1,CCK,KRIT1,LRBA,PCYT1B,AKAP6,HAPLN1,VCAN,DBI,EDN1,ENO2,TUBB3,FGF1,GABRA3,GABRB3,GABRG1,GABRG2,BRD8,CRCP,GPD1,GPD2,GUCY1B1,TNFAIP8L3,IGF1,MITF,NPR2,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PLIN1,TRHDE,PPARA,PRKACB,PRKCB,MAPK3,PTH1R,SST,SSTR2,CDK20,VIPR2" Drug CID000011313 Congo red Stitch 4.02E-03 1.00E+00 2.47E-02 2.79E-01 24 120 "APAF1,APLP1,APOC2,CDK13,GAL3ST1,DYNC1I1,ENO2,PPP1R1B,PPARGC1A,TCERG1,PACSIN2,KITLG,MXI1,OGG1,PIK3C2A,FSD1,PTX3,QDPR,PID1,ATXN7,FOXRED1,UBC,HPS4,JPH3" Drug 1044_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.03E-03 1.00E+00 2.48E-02 2.79E-01 32 174 "CLK4,BRAP,OSBPL1A,ST3GAL5,ARMC8,CSNK1E,MBNL2,ARMCX1,FHL1,CINP,FAM49B,GRB10,DIDO1,MAP4K5,HMGCR,HSF2,MAP4,NUCB2,MBOAT7,PPM1B,PRKAR1B,MORC4,RNASEL,HSPA4L,SH3BGR,FNDC3A,TSPYL2,POGZ,JMJD6,SIN3B,TRIM2,FXR1" Drug ctd:C024746 tobacco tar CTD 4.03E-03 1.00E+00 2.48E-02 2.79E-01 32 174 "KDM5D,CD86,CRLF1,CNTN1,GDA,CNTNAP2,AIF1L,DMD,DTNA,ZNF585B,FECH,MEX3B,FOXF2,SEMA4D,FYN,GPR37,GSN,MAP2,SCAMP5,IDNK,NRCAM,PALM,SH3KBP1,VSTM2L,ZIK1,NEK11,MEG3,RTN1,UCHL1,ZIC2,TRIM9,TFIP11" Drug CID000005070 riluzole Stitch 4.03E-03 1.00E+00 2.48E-02 2.79E-01 32 174 "ASIC1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CACNA2D2,ASIC3,NRG2,GRIN3A,GABRA3,GABRB3,GABRG1,GABRG2,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,KCNK3,KCNN1,KCNN3,MAP2,PKD1,RYR3,SCN7A,NFASC,VGF,SLC17A7" Drug CID000036811 dobutamine Stitch 4.04E-03 1.00E+00 2.49E-02 2.80E-01 27 140 "ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,ALDH7A1,AP1M1,CACNA2D1,VCAN,DBT,DMD,ERBB2,FOXO3,MSTN,BVES,HP,IGF1,ITGA7,KCNJ5,PDE3A,PDPK1,TET1,SMUG1,TSC1,TSC2,RICTOR" Drug 6220_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.07E-03 1.00E+00 2.50E-02 2.81E-01 33 181 "APAF1,KRIT1,DCAF8,SACS,EGR3,EIF5,TBC1D16,RACK1,CAMKK2,B4GALNT1,GHR,RNFT2,MBP,PDCD2,PIK3R1,MAPKAP1,ZSCAN32,ZDHHC4,RIC8B,AP1AR,SEC14L1,KBTBD4,CDK5RAP2,CDK19,TBL1X,ZMAT3,TIAM1,SMUG1,EVI5,MARCH8,UBE3B,PHTF2,NETO2" Drug 3257_DN Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "ABHD6,ARNTL,ARRB1,NCOA1,MPDZ,CFLAR,LHX2,CREM,EXOG,FGFR3,BAIAP2,SYNCRIP,ANKFY1,PDLIM5,INPP5K,RAB40B,FERMT2,AGFG1,MAP4,NEK1,SETD4,SUPT20H,KIF16B,TTC17,PDZRN3,CLASP2,JMJD6,TACC1,MTCL1,MCF2L,AGTPBP1,TRIO,VAV1,ZIC1" Drug 2854_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "ADORA1,NME5,PLA2G4C,MARK4,CFLAR,CACNA1I,CA4,SPAG9,SLC16A4,SYNGR3,LRIG1,VCAN,DOCK4,DBT,FGFR1,FHL1,TRAF3IP2,MSL3,TDRKH,MIA2,ZNF862,PLCD1,PRKAR1B,MAPK10,CCDC40,SLC25A36,SEC14L1,SH3BP2,PEX26,KDM4C,THSD1,TK2,ZKSCAN5,UBE3A" Drug 1177_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "ADRB2,CASK,CAPN3,HOMER3,ARMC8,VCAN,NR1D2,PCOLCE2,ENO2,SYNCRIP,CGREF1,GRB10,IRF8,IFI16,KCNN2,KIF2A,MAN2A2,MAP4,NME4,ENPP2,RETREG1,RET,SUPT20H,HSPA4L,FERMT1,KANK1,EXOC7,TNS1,UBTF,ZNF24,FTSJ1,PRDM10,NAV3,SMIM8" Drug 4209_UP Zardaverine [101975-10-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "CDK13,N4BP2L1,CACNA2D1,HIP1R,RUNX1T1,ARHGEF2,CHN2,FAM149A,WHRN,SLC4A8,GAL3ST1,CTH,PITPNC1,HIPK3,PLXNC1,IRAK4,CORO2B,KAT8,GLI2,GRM2,ICA1,KCNJ5,PDE4B,SERPINI1,SMOX,PRKAR1B,MAPK7,WDR25,RASGRF1,CCDC102B,EMID1,ST8SIA1,SPART,RPGRIP1L" Drug 5239_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "APBB2,APC,ST3GAL5,SYNJ2,RUNX1T1,CLGN,ABCG1,CTH,TBC1D5,SPOCK2,CDON,SLC12A6,FCF1,MBNL2,ING4,EZH1,SRCAP,POLL,GPER1,GRIK5,SMAD1,MX1,ZNF862,NF1,PLCD1,RETREG2,CARF,SH3GL3,CDK19,PCDHA5,UCHL1,VIPR2,MARCH8,TIGD6" Drug 5493_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "SYN3,ADORA2A,AMPD3,BIN1,ANK2,HAP1,QKI,FAM149A,PDE4DIP,ARHGEF4,GIT2,MED12,F5,ARMCX1,DCTN2,CNTRL,IL6ST,INPP5B,LSS,PDE4A,PGAM2,PLCD1,PTPRD,NEK11,RPS6KA2,ZNF821,PDZD2,CLSTN2,ZC4H2,TRIM2,CRTC1,PCDHA6,GPR161,SLC17A7" Drug 5980_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.09E-03 1.00E+00 2.50E-02 2.81E-01 34 188 "ADRA1D,APAF1,APOC1,PPFIA3,NRP2,BMPR1B,IL33,VCAN,OPTN,EGFR,MBNL2,ING4,ETV1,FGFR1,LILRA2,STON1,KCNQ3,MARK1,MATN3,MMP16,PALM,CDK18,BCAS3,TMEM231,KCTD17,KIRREL1,STK32B,SH3BGR,HKDC1,AMBRA1,KIF13A,TROVE2,TBL1X,THRA" Drug 3893_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "KCNAB2,APLP1,CDK13,CAMK2B,CAMK2G,NECTIN3,AKAP12,ZNF804A,PLXNC1,STX2,ERCC2,FGF12,FGFR1,GLYR1,GRM8,INPP5B,KHK,TM6SF1,KITLG,MMP16,ADAM22,OGG1,PDE4A,PLCD1,PRKCB,MAPK10,ELOVL2,RASA3,FNDC3A,ZKSCAN3,SMARCD3,SPTAN1,STX1A,PLCB1,SMG6" Drug 4549_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "LTBP4,FAM135A,APC,LGR5,CDK13,ATP1A3,SLC4A4,DLGAP1,PICK1,AKAP5,ENTPD4,BRINP1,CDON,DTNA,NRN1,FGF1,AFF2,FYB1,GAD1,GLI2,LIG4,MYO7A,OPRL1,LRRN3,PRKCB,BCAS3,RASGRF1,KHDRBS2,FRMPD1,NLGN1,SLC11A1,ARHGEF9,TPM1,SSBP2,VGF" Drug 5399_DN Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "RALGAPA1,NME5,APLP1,CFLAR,UBE2L6,FOXN3,TAOK2,SLIT2,RCHY1,SH2B1,PPP6R2,ZNF804A,DTNA,IGSF6,ZNF589,DISC1,GCNT2,GLYR1,GSN,INPP1,NF1,ELOVL2,SBF1,AMBRA1,SPTAN1,PLCB1,FBXW11,TNS2,CRTC1,PCDHA6,SLC44A1,TK2,CABIN1,ZKSCAN5,VGF" Drug 3452_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "C1QTNF3,APBB2,GAS7,ARHGDIG,ATP6V0A1,CFLAR,AKAP7,WHRN,ENTPD4,GREB1,RIPOR2,SPOCK2,VPS13B,NCALD,FGFR1,BAIAP2,FHL1,SRCAP,KCNH2,MEF2C,ZNF862,PLXNB1,MINDY2,ZSCAN2,RPS6KA2,PEX26,SLC22A4,FAIM2,ZBTB43,COBL,SYT5,TRIM2,CRTC1,PDIA2,EVI5" Drug 5820_DN Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABHD6,ADAM15,CFLAR,SLC25A14,CSF1,RUSC2,DYNC1I1,EIF5,CDKL3,FECH,POMT1,FAM69A,INPP5B,MAP4,MPP2,MYO6,PDE1C,PTCH1,SH3TC2,SUPT20H,TRA2B,ZKSCAN3,SMARCC2,CDK5RAP2,LHPP,ST5,FBXW11,WSCD1,ZNF34,LMF1,XRCC4,ZFAND5,NAV3,ITM2C,PLSCR4" Drug 4686_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "C1QTNF3,BIN1,CFLAR,ARHGEF2,ARMC8,WHRN,CSF1R,DZIP3,GREB1,BRINP1,DBN1,JAKMIP2,RUSC2,RCAN1,MBNL2,CDKL3,FYB1,GAD1,SEPT9,LSS,MAP4,MPP2,NF1,MBOAT7,CNNM2,RGS12,RPS6KA2,KDM4B,ARHGAP26,ZEB1,TRIM2,TMPO,TRIO,KCNK12,TIGD6" Drug 5626_DN Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NDRG2,SEMA6A,GAS7,ATP6V0A1,MTMR3,GYG2,PDE4DIP,JAKMIP2,MFAP3L,EIF4G2,STX2,ZNF589,CGREF1,OGA,MALT1,MSL3,FERMT2,CACFD1,NF1,NPTX1,NLE1,SLC25A23,ZNF821,ZFP30,ASAP3,AMBRA1,DOK5,SEPT8,PLCB1,TNS2,CHST8,RUNDC3B,ZNF711,MAP3K12,GDPD5" Drug 5008_DN Fluspirilen [1841-19-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "CFLAR,ARHGEF7,SLIT2,LHX2,ABCG1,MFAP3L,FBXL5,LYPD1,MAMLD1,ENO2,SCML2,FGF12,BAIAP2,SEMA4D,INPP5K,RAB30,MMP16,LYRM9,ZNF862,RETREG1,LRP12,PPP2R2B,CEP97,SH3BP2,FBXO11,FAM214B,PDZRN3,VPS13A,EXOC7,ZNF34,VGF,EMSY,GDPD5,MPPE1,SMIM8" Drug 900_UP 5186324; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "APAF1,APBB2,ARHGDIG,C5,CACNA2D2,HOMER3,GREB1,DBT,SUGP2,EIF4G2,DENND4A,CDKL3,PDLIM5,OGA,FYB1,GNG4,CNTRL,GRM8,RNFT2,HNMT,MITF,PPP5C,PRKAR1B,GTDC1,PPP4R3A,ZNF430,SLC22A4,MTCL1,EXOC7,PCDHA6,THRA,TRIO,RUNDC3B,ZNF24,FIP1L1" Drug 6651_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABR,AMPD3,APAF1,CFLAR,MTMR2,CBFA2T2,CNOT8,AATK,CHRDL1,TOM1,EDIL3,HIPK3,CELSR3,COQ7,STX2,ETV1,SPACA9,ELOVL5,SYNPO,LYRM9,NF1,KIRREL1,FBXW7,UNC5B,SS18,ST5,SYT1,TCF4,ZEB1,GPR161,CABIN1,RPRM,VGF,ZNF45,SENP7" Drug 7033_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "SEMA4G,MARK4,SCAPER,MTMR3,GYG2,LDLRAD4,CALB2,SLIT2,ENTPD4,AKAP12,CSF1,DMPK,DTNA,PHF20L1,ING4,RRAGB,F5,DISC1,CNTRL,IPO5,MAP4,KITLG,PLTP,GRAMD1C,PRODH,PTCH1,PDZRN3,PLCB1,EXOC7,CUX2,HIRA,PLPPR2,LAT2,KCNK12,NDRG4" Drug 6058_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "AMPD3,GAS7,CDK13,ATP1A3,CACNA1G,CDH2,CBARP,FAM149A,RIPOR2,SNPH,SPOCK3,DUSP9,SRPK3,MTSS1L,ZNF391,FHL1,ZNF44,GAD1,GNAL,GRM8,ATXN2L,IRF8,KCNN1,LAMA2,NTRK3,SAMD9,EMID1,SLC11A1,ARHGAP26,WSCD1,TPM2,VLDLR,KCNAB1,PARP11,JPH3" Drug 6059_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASIC1,SRPX,APOC1,ARRB1,CFLAR,CACNA1I,USP2,CBFA2T2,ARHGEF2,PLEKHB1,RCHY1,NECTIN3,PDE4DIP,MAML1,HIPK3,ZNF589,FGFR1,SRCAP,GRIK5,MAP4K5,MAP4,MITF,MMP16,ADAM22,ZNF862,SLC25A23,PRKAB2,PRODH,SBF1,SNCA,PHLDB1,DICER1,CHST8,KCNK12,MARCH8" Drug 1968_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "APBB2,SEMA4G,N4BP2L1,ADAM23,ST3GAL5,CAMK2B,RUNX1T1,CD86,SPOCK2,DBT,RCAN1,PHF20L1,EXTL2,SEC23B,SEMA4D,OGA,LILRA2,NEFH,OPA1,PLCB2,SBF1,ATXN2,SLC11A1,MAPKBP1,DOP1A,SP2,ZSWIM8,SS18,ERBIN,DIP2A,TK2,TMPO,CHST5,UBE3A,RNF146" Drug 7423_DN Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "FAM131A,MADD,EIF4G3,PLEKHB1,PDE4DIP,DCAF8,ZNF337,DBN1,SEZ6L2,KAT8,ANKFY1,TRMO,CGREF1,SRCAP,GRB10,FAM69A,MEIS2,SLC25A23,RETREG2,PRKAR1B,TMEM231,GTDC1,SH3BP2,EPN2,ZKSCAN3,GLT8D1,ZBTB43,TSPYL2,CEP68,NSFL1C,PLPPR2,VAV1,LMF1,SEMA3B,KAT6A" Drug 5329_DN Erythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "AK2,CDC42BPA,APBB2,TAOK2,LHX2,ARMC8,COL4A5,DZIP3,SGSM2,DTNA,OPTN,CELSR3,SUGP2,ENO2,SEMA4D,FYN,DISC1,BTN2A1,MAP4,MBD1,NPR2,SLC11A2,FA2H,PRKAR1B,CEP97,RNASEL,SLC22A4,TMCC1,CDK19,ZBTB43,TSPYL2,TRIM2,TNS2,KAT6B,CABIN1" Drug 7101_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "KCNAB2,PPFIA3,MADD,MARK4,STOML1,ABCG2,CREM,HINFP,CSNK1E,ARHGEF4,PPP6R2,USP21,AHDC1,HTATSF1,MUM1,HNMT,DHX35,NF1,SETD4,PDCD2,PRODH,RIPOR1,CCDC25,SH3BP2,FBXO11,PEX26,BTBD7,ZHX3,IQSEC2,THSD1,PRRC2C,TP53BP1,HIRA,EVI5,EPM2A" Drug 5329_UP Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ADD1,AP2A2,APC,APLP1,APOC1,CDK13,ST3GAL5,LDLRAD4,CBR1,CLGN,NRG2,PDE4DIP,GIT2,FEM1B,FGFR1,TXNL4A,GRB10,KCNH2,MAP4,MAPT,NACA,NEK1,NF1,NFYA,RGS3,FNDC3A,ANKRD6,KANSL3,ERC1,ATP10B,TMPO,PARD3,TRIO,PLPPR2,DNALI1" Drug 6101_DN Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "GAS7,NUMB,GYG2,CNTN1,CRY2,CSF1R,DTNA,HIPK3,VPS13B,FAM198B,FHL1,CNTRL,RASSF8,ELOVL5,INPP5B,MAPT,TM6SF1,ADAM22,PLCD1,SLC25A23,FAM184A,SBF1,ZNF821,SNCA,KIF13A,KDM4C,IQSEC2,PHLDB1,VPS13A,PLCB1,ZNF34,CDK20,VLDLR,WIPF1,GAN" Drug 6878_UP "H-89, Dihydrochloride; Up 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASPHD1,ATP6V0A1,QKI,CRMP1,CSNK1E,DOCK4,DBT,DTNA,VPS26C,ZNF589,PDLIM5,MAP4K5,MUM1,C2orf72,KCNN1,ADAM22,CNOT4,PALM,PIK3R1,PPP2R2B,PPP3CC,GSTCD,RPS6KA2,CLIP1,ZNF821,SLC6A8,SIRT2,SMARCD3,LIMCH1,CLASP2,CLSTN2,SS18,ELOVL4,ARHGEF9,TMPO" Drug 6448_UP Estrone [53-16-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "SYN3,ABHD6,ADORA1,CAMK2B,QKI,AKAP7,WHRN,ARHGEF10,PDE4DIP,PHF14,HDAC9,ARMCX2,RUSC2,EGR3,EPHB1,ZNF589,HPCAL4,ANKFY1,ERAP1,TMEM8B,HLF,MAPT,AFF1,MMP16,CNOT4,LRP12,PRKAR1B,SH3BP2,SLA,PKNOX2,ZHX3,HECW1,PEG10,PLCB1,TRIM2" Drug 1239_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "APAF1,ZBTB10,WASF1,MYRF,IL33,SRSF11,WHRN,AKAP12,DCAF8,SPOCK3,ING4,CORO2B,SEMA4D,ERAP1,MSL3,PRRC2B,STON1,HNMT,SCIN,MAPT,MGAT3,ZNF862,OCRL,GDPD2,FBXO11,SLC4A3,ELOVL4,MCF2L,EXOC7,TRIM2,SZT2,THRA,CLIP2,HPS4,PLSCR4" Drug 6098_DN Streptozotocin [18883-66-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ALCAM,SCAPER,GYG2,CFAP410,KYAT1,SRSF11,ARHGEF4,RIMS2,GIT2,MFAP3L,DUSP9,EGR3,ING4,ZNF589,FGF12,FGFR1,FHL1,IQCG,ALDH1L1,USP19,GRM8,KPNA5,MIA2,LRP12,MAPK7,ZSCAN32,CEP97,ZDHHC14,RBM34,KDM4B,IQSEC2,PHLDB1,VPS13A,TRIM2,PCDHA5" Drug 3816_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "BCAS1,PRX,ARHGDIG,CACNA1A,HAP1,USP2,DCLK1,CDO1,B4GALT6,AKAP6,CSF1,CSF1R,RIPOR2,DTNA,MBNL2,SIGLEC8,ICA1,KCNJ5,LAMA2,MATK,KITLG,NF1,NOVA1,NPTX1,NPTX2,ZSCAN32,PNMA8A,EMID1,DOCK9,TLR4,OSBP2,SLC30A4,PRDM10,KCNAB1,PHTF2" Drug 5444_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "AMPH,APOC1,PPP4R4,ARHGEF7,CA4,SLC16A4,RCBTB2,FOXN3,SLIT2,WHRN,BAG4,CREM,DCAF4,MFAP3L,ECM2,ING4,IGSF6,FGFR1,C2orf72,KCNF1,MSI1,ADAM22,PDPK1,PLTP,CEP41,RELN,RPS6KA2,OGDHL,ZNF423,IQSEC2,MTCL1,DOCK9,TK2,TNS1,TRIO" Drug 5252_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ALCAM,SYNJ1,CFAP410,SOCS6,HOMER3,JAKMIP2,HIPK3,MBNL2,FGF13,EFCAB2,TRMO,GNG4,GPER1,MAP4K5,HNMT,IL6ST,INPP5B,JAK2,KITLG,MMP16,MPP2,ADAM22,NF1,NFYA,CNOT4,TCP11L1,CXXC4,ZC3H13,TROVE2,ST5,PLCB1,AP4E1,KCNK12,PHTF2,SENP7" Drug 1296_DN Androsterone [53-41-8]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ACTN1,AP2A2,EP400,BCL7A,CAMK2G,HOMER3,CST3,ZNF337,TM9SF4,DBN1,KIAA0753,TRMO,LILRA2,IRAK3,JAK2,KIF2A,IPO5,MAN2A2,MEF2C,PDPK1,MAPK12,AMBRA1,SLA,SLC6A8,SMARCC2,ZHX3,SS18,SEPT8,NSFL1C,JMJD6,TBL1X,TCF4,CABIN1,UBTF,LAMP5" Drug 4644_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ADCY6,MTUS1,CDK13,SLC4A4,MYRF,SPAG9,CNOT8,QKI,HOMER3,WHRN,VCAN,TBC1D5,DBN1,EXOG,RCAN1,FCF1,FAM13A,MBNL2,ETV1,SHISAL1,INPP5B,MPP2,OCRL,FA2H,TMEM231,RPS6KA2,ZFP30,FBXO11,SS18,TK2,TSC2,SSBP2,EVI5,SMIM8,PHTF2" Drug 834_UP 5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "CDC42BPA,FAM131A,PPFIA3,CDC14B,ST3GAL5,SCAPER,CREM,LRIG1,PDE4DIP,CTH,ARHGEF4,MFAP3L,CELSR3,IRAK4,ENO2,ARMCX1,SRCAP,AHDC1,GNG4,BTN2A1,GIT1,LYRM9,MYO6,PRPH,MORC4,RNASEL,ROBO1,FNDC3A,NLGN1,ZKSCAN3,THSD1,KIAA0930,TK2,WBP2,EPM2A" Drug 4318_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ADD2,ADORA2A,AMPD3,APC,LGR5,RASL11B,ADAM15,SYNJ1,DTNA,EDN1,EGFR,FLT1,ZNF44,ADAM28,GLYR1,GPER1,HLF,KITLG,NELL2,NF1,NFYA,NPTX1,NPTX2,PFKFB4,PPP5C,PTPRN2,RGS4,CPEB3,FNDC3A,SLC11A1,SLC12A4,SNCA,ZSWIM8,TACR1,LAT2" Drug 3712_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "LTBP4,BEGAIN,AMPH,PPP4R4,ARSE,DNAH17,RASL11B,KALRN,CBS,ARHGEF2,SULT4A1,AKAP12,CSF1,CNTNAP2,MFAP3L,SV2B,KAT8,OLFM1,AFF2,CPLX2,GLUL,AP4S1,ATXN2L,ITPKA,MATN3,NNAT,NOVA2,NPTX1,ABLIM3,ZHX3,PCDHGA10,HEY1,TRO,LAT2,SEMA3B" Drug 5330_UP Rolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "C1QTNF3,APC,EPB41L5,ADGRB2,LDLRAD4,SOCS6,RAB26,JAKMIP2,CDKL3,FGFR1,PRELID3A,SRCAP,GRM8,NF1,NNAT,PCBP3,CCSER2,PLEC,PRODH,TMEM104,PTN,ZNF821,FRMPD1,FNDC3A,ZKSCAN3,MAPKBP1,KDM4B,TSNAXIP1,ZBTB43,PLCB1,PCDHGA10,ZNF34,PARD3,GDPD5,HPS4" Drug 4705_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "RALGAPA1,BIN1,CDK13,ADGRB2,CA4,CSF1,GREB1,EDN3,EDNRA,OPTN,MTSS1L,HPCAL4,OGA,NEU3,GRB10,IRAK3,TJAP1,MEF2C,MID1,NEFM,CNOT4,RGS4,TCP11L1,FRMPD1,NLGN1,CCDC88A,SMARCD3,CLSTN2,TACR1,PCDHA5,RIMBP2,HIRA,WIPF1,ITM2C,AP3B2" Drug 889_UP 5286656; Up 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "SPARCL1,AMH,AMPD3,BIN1,LRRFIP1,PICK1,VCAN,RCAN1,CELSR3,MBNL2,AASS,ST3GAL6,FHL1,EFCAB2,GLYR1,GNAL,PRUNE2,CNTRL,KCNH2,KIF2A,LSS,MAP4,MMP16,CDK18,NEK11,ZNF821,NLGN1,ANKRD6,SLC11A1,SLC22A4,CLSTN2,TPM2,SLC30A3,EVI5,TIGD6" Drug 7022_UP Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ADD2,ADRB2,APBB2,ARHGDIG,SYNJ2,TAOK2,SH2B1,PDE4DIP,ARHGEF4,DTNA,OPTN,EGFR,EGR3,MTSS1L,ZNF589,PRKAG2,AFF2,NEU3,TXNL4A,ELOVL5,IPO5,MAP4,LYRM9,NF1,NLGN1,FAM214B,RBM34,ERC1,PLCB1,EXOC7,PLPPR2,KCNK12,ZNF24,ZNF45,SEMA3B" Drug 2336_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "BRAP,SLC4A4,ADAM15,CA12,CAST,SCARB1,SOCS6,QKI,VCAN,ARHGAP32,SGSM2,CELF1,OGA,TRAF3IP2,DHX35,ICA1,ITGAM,ITPKB,SMAD1,MAP4,OGG1,RETREG1,CCDC25,FBXW7,TCP11L1,ARHGEF40,DIP2A,ANKRD12,FLRT2,PLPPR2,ATP6V0E2,NT5M,URM1,TIGD6,AAAS" Drug 2761_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABHD6,AK2,APBB2,PPFIA3,NCOA1,BCL7A,BMP7,MTMR3,ENTPD4,LRIG1,CTH,PPP6R2,MAML1,FEM1B,NCALD,BAIAP2,DISC1,LSS,MBP,MITF,NPR2,SLC11A2,CNNM2,RNASEL,GSTCD,TCP11L1,SBF1,CCDC92,THSD1,ZNF34,TIAM1,TRIO,FTSJ1,MPPE1,PHTF2" Drug 4360_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABHD6,BIN1,ARRB1,SLC2A11,ADAM15,SCAPER,CFAP410,CRLF1,PLEKHB1,TAOK2,HOMER3,ABCG1,PDE4DIP,DMPK,MED12,GALC,GLYR1,RAB30,KCNF1,KCNH2,LSS,PLXNB1,PRKAR1B,RAD51D,RGS12,SH3BP2,SMARCA4,SMARCD3,ZSWIM8,CAMTA2,EXOC7,TMEM121,CDK20,ZNF74,HPS4" Drug 6754_DN Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NDRG3,BIN1,APOC1,PDE8B,STX16,CACNA1I,CBFA2T2,ARHGEF2,PLAA,RAB26,ENTPD4,NCOR2,CNTNAP2,DCAF8,RCAN1,HSD17B14,ANKFY1,FYB1,GPD2,LPAR4,MIA2,SCAMP5,MN1,NF1,CNOT4,PIK3R1,ZSCAN32,FBXW7,CSRNP3,CCDC88A,ZBTB43,LHPP,BEX4,WNT7A,PHTF2" Drug 414_DN "estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "AGT,C1QTNF1,ARRB2,NCOA1,SLC4A4,CAST,CBFA2T2,SYNGR3,CD38,ARHGEF2,QKI,LY86,CLIP3,RCAN1,ING4,EPHB1,FOLR2,LILRA2,MAN1B1,NEK1,NELL2,PMP22,FSD1,TCP11L1,ZFP30,ASAP3,LIMS2,SNAP25,TSPYL2,STX1A,EXOC7,DMXL2,VSNL1,SPHK2,MAP3K12" Drug 5077_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NME5,KCNAB2,RGS20,FOXN3,TAOK2,EDIL3,FAM13A,ING4,CDKL3,ETV1,VPS26C,PDLIM5,TMEM8B,INPP5K,SHISAL1,MIA2,PLCD1,SLC25A23,SNRK,TMEM104,RPS6KA2,SCN8A,DZIP1,SLC6A8,SLC22A4,TMCC1,SEPT8,VPS13A,CRTC1,TK2,TPM2,WIPF1,MAP3K12,PHTF2,DPF3" Drug 5318_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABR,ADCY6,BRAP,OGT,APC,NCOA1,EIF4G3,KRIT1,FOXN3,RHOBTB1,DNM1,ANKFY1,INPP5K,GHR,MALT1,RNFT2,SLC2A6,MMP16,SLC11A2,PLEC,PRKACB,USP47,RNASEL,GALNT10,KBTBD4,MAPKBP1,GLT8D1,ZBTB43,SS18,SYT1,TACC1,TRIM2,SSBP2,HIRA,LMF1" Drug 919_UP carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "AMH,BIN1,AMT,APBB2,KIF1A,ADGRB2,CCK,ARHGEF2,CABP1,RCHY1,RGS6,RIMS2,AASS,EIF4G2,ERCC2,CDKL3,ST3GAL6,ZNF589,IQCG,MALT1,KPNA5,ADAM22,NF1,RGS12,KCTD17,SCN2B,MRAS,ASAP3,TSPYL2,CLSTN2,SYT5,TRIO,VIPR2,VLDLR,NLRP3" Drug 3199_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ALK,APOC1,HAP1,CSF1,CNTNAP2,SNPH,HDAC4,SV2B,SLC12A6,ERBB2,PTK2B,OLFM1,AGAP2,FLNC,PDLIM5,OGA,ATXN2L,KCNH2,KIT,TAGLN3,NOVA2,PALM,GPR85,PGAM2,PRPH,RPS6KA2,EPN2,OGDHL,CDK19,CLSTN2,R3HDM1,PIK3R5,AMACR,TRO,FAM155A" Drug 7448_UP Bacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "BIN1,CDC14B,PPP4R4,CFLAR,CAMK2G,USP2,CBFA2T2,MAGI1,SLC4A8,PDE4DIP,CTH,OGA,DISC1,SRCAP,USP19,GLYR1,RNFT2,HLF,RETREG1,PLXNB1,PPP2R2B,RGS4,GSTCD,RPS6KA2,SLC11A1,SNCA,UNC5B,STX1A,PLCB1,ANKRD12,ZNF34,PIK3R5,ZNF32,REEP1,SLC30A3" Drug 4172_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "APC,CFLAR,CACNA1G,ARHGEF2,AKAP6,CNTNAP2,BRINP1,RUSC2,DMPK,EDN1,C3orf18,STX2,CORO2B,FHL1,NSG1,FYB1,ALDH1L1,GCNT2,HAS2,AFDN,MMP16,NOVA2,NTRK2,SAMD9,PTPRB,FRMPD1,SLC11A1,IZUMO4,ATP10B,DOCK9,HIF3A,TEK,WIPF1,ZNF711,SLC17A7" Drug 1290_DN Droperidol [548-73-2]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ACTN1,CDK13,NCOA1,SH2B1,PPP1R16B,DBN1,SLC12A6,SUGP2,MRNIP,PTK2B,KAT8,FGFR1,TRAF3IP2,STON1,LPAR4,CLASRP,MAP4,MAPKAP1,MBOAT7,POLG,RAD51D,RXRA,AMBRA1,NUBPL,SIRT2,SLC11A1,SMARCC2,MAPKBP1,KDM4B,TSPYL2,CEP68,PRRC2C,EXOC7,SYNE1,KAT6B" Drug 1836_DN Sulfaphenazole [526-08-9]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "CFLAR,CAPN3,CD86,HOMER3,SEC31B,HINFP,PPP1R16B,DCAF8,TM9SF4,KIAA0586,DBT,RCAN1,SUGP2,KMT5B,ING4,RASGRP2,CINP,PRRC2B,IPO5,NFYA,PDE4B,LRP12,POLG,MAPK3,SAMD9,C1orf109,RDX,REV3L,PCMTD2,DHX30,TLR4,TMPO,TSC2,XRCC4,SPHK2" Drug 2924_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ADORA1,AMPD3,SEMA4G,HIP1R,CBFA2T2,CHN2,SULT4A1,AKAP6,FAM169A,SPOCK2,KLHL3,EDIL3,AFF2,GNG4,ADAMTS13,GSN,LAMA2,MAPT,ADAM22,P2RY1,PDE4A,PPP2R2B,GTDC1,TCP11L1,KCNIP1,CNKSR2,SLC6A11,SP4,IZUMO4,ZC3H13,SPTB,TACR1,SZT2,CDK20,SLC17A7" Drug 7018_DN Glafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASPHD1,CDC42BPA,PPFIA3,NUMB,ADAM15,CFLAR,SPAG9,LHX2,RAB28,CREM,CSNK1E,PPP6R2,EIF5,MRNIP,ATP2C1,COPS8,DHX35,OPA1,POLG,PPP3CC,ZCWPW1,TRAPPC13,ATXN7,SGK1,AMBRA1,SYBU,TTC17,UHRF1BP1L,CDK19,CEP68,SATB2,TMPO,KLC2,ZNF45,URM1" Drug 3663_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABHD6,ACTN1,NDRG3,ADRA1D,PKP4,APBB2,APC,APOC1,CCNT1,DAPK3,SLC12A6,RCAN1,FEM1B,MBNL2,ERCC2,TRAF3IP2,CACFD1,ELOVL5,MBNL1,NF1,NFYA,SERPINI1,RAD51D,ENOX1,KIRREL1,ELMO2,TMCC1,SPTAN1,EXOC7,FBXW11,TRIM2,TMPO,LMF1,DPF3,RNF146" Drug 3001_UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ABHD6,C1QTNF1,APC,CDC14B,CAMK2B,HIP1R,PLEKHB1,AKAP5,NCOR2,RIPOR2,DAPK3,MFAP3L,DCTN2,GAA,POLL,GPD2,GRIN2C,ADAMTS6,IGF1,KCNN3,MMP16,MYO7A,P2RY13,NPY,NTRK3,PDE1C,BEND5,GAL3ST4,RYR3,SEMA6D,ASAP3,PREX2,SYT1,HIF3A,SSBP2" Drug 1732_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NDRG2,AMT,ARNTL,SLC4A4,SEC31B,PPP1R16B,DOCK4,CDKL3,ZMYND10,FGFR1,PCYOX1,INPP5K,NXPH3,NUCB2,SERPINI1,CCSER2,RETREG1,PLCD1,LRP12,PTX3,SATB1,SBF1,DOP1A,NXT2,RGL1,STXBP1,NSFL1C,VPS13A,TCF4,SZT2,R3HDM1,TNS1,NPDC1,MARCH8,SMIM8" Drug 6052_DN Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "C1QTNF3,LTBP4,APBB2,EPB41L5,CFLAR,CACNA1I,CAST,SYNGR3,STOML1,QKI,CREM,ENTPD4,AKAP12,CTH,GREB1,DTNA,KAT8,TXNL4A,HNMT,INPP5B,LMO2,CNOT4,FBXW7,SBF1,SEC14L1,FBXO11,ANKRD6,KDM4C,ELOVL4,PHLDB1,NSFL1C,TRIM2,ZKSCAN5,HPS4,ST7" Drug 4324_DN Acacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "BIN1,AMT,APC,APLP1,SLC4A4,ARHGAP33,FOXN3,B4GALT6,HAPLN1,SLITRK5,FAM131B,CHRDL1,TOM1,SEMA4D,SRCAP,AHDC1,POLL,GSTM5,TJAP1,NTRK2,PDE4A,FA2H,C1orf54,SLC4A3,SPTB,THSD1,ZEB1,CABIN1,WBP2,TRIO,VIPR2,LAT2,SPHK2,SEMA3B,NAV3" Drug 1539_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASIC1,ABHD6,AGT,APAF1,SCAPER,GYG2,USP2,DLGAP1,WHRN,CSF1R,FAM169A,GREB1,SEC14L5,INTS1,JAKMIP2,MFAP3L,RASGRP2,CDKL3,REEP2,OLFM1,BAIAP2,HPCAL4,ADAMTS13,TJAP1,IPO5,CDK18,CEP41,RGS3,SH3GL3,CNKSR2,TROVE2,TIAM1,TK2,RUNDC3B,KAT6A" Drug 6729_DN Erythromycin [114-07-8]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "RALGAPA1,BIN1,ATP1A3,SEPT7,STOML1,HOMER3,CSNK1E,VCAN,SPOCK3,ETV1,IQCG,B4GALNT1,ERAP1,INPP5K,MSL3,HNMT,IL6ST,LIG4,TAGLN3,WDR25,PTN,KIRREL1,MAPK12,SCN8A,FBXO11,TMCC1,ARHGAP26,SPTAN1,KIAA1107,DOCK9,HIRA,WIPF1,WNT7A,ZNF711,NT5M" Drug 7362_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "PPFIA3,MARCH3,NCOA1,MPDZ,ARHGEF1,HOMER3,AKAP7,ARMC8,TMCC2,HSD17B14,ZNF589,ATP2C1,DISC1,COPS8,FAM69A,MITF,ZNF671,TCP11L1,FNDC3A,SLC22A4,LIMCH1,SS18,ELOVL4,SYNE2,ARHGEF9,SYT1,KIAA0930,SYNE1,TK2,UBE3A,ZBTB14,SMIM8,PHTF2,ADAMTSL3,RNF170" Drug 7432_DN Fenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "APC,NCOA1,ARHGEF1,TAOK2,HOMER3,SIPA1L1,PDE4DIP,DTNA,EIF5,STX2,GPD2,SLC2A6,MAPT,MITF,MMP16,NEK1,RETREG1,SLC25A23,PLXNB1,PMP22,PRKAR1B,SAFB,MAPK12,FERMT1,PPP4R3A,EPN2,LHPP,ELOVL4,STX1A,KANK1,NSD1,NPL,LMF1,REEP1,ST7" Drug 3613_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NDRG2,SEMA6A,LTBP4,BIN1,GYG2,CACNA1I,HIP1R,USP2,NRXN3,SULT4A1,CSF1,TMCC2,EDIL3,AFF2,RASL10A,HPGDS,GNAO1,LILRA2,HNMT,SHISAL1,MGAT3,FXYD7,NF1,LRRN3,PRKCB,GDPD2,ELOVL2,C1orf54,STUM,SLC6A8,HECW1,PEG10,ZBTB43,SYN2,WSCD1" Drug 3812_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASPHD1,ADD2,EPB41L5,ALDH7A1,BACH1,CAMK2B,CACNA2D2,PICK1,IQCK,CNTNAP2,MFAP3L,SPOCK3,ECM2,DUSP9,EDN1,DENND4A,ETV1,PRELID3A,MSL3,GNG4,GRIK5,HSF2,JAK2,MATN3,MEF2C,MN1,PDE4D,ZCWPW1,KCTD17,RASA3,FAM214B,ZNF334,NXT2,SMIM8,PHTF2" Drug 866_UP ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "ASIC1,CDC14B,EIF4G3,GYG2,HOMER3,PDE4DIP,PPP6R2,ZNF337,DUSP9,CDKL3,F8,FAM198B,EFCAB2,FAM49B,FYB1,ERAP1,LPAR4,GRM8,HMGCR,LIG4,AFDN,LYRM9,PTPRB,KHDRBS2,KCTD17,FUZ,NLGN1,KANSL3,ELMO2,ZNF415,ZBTB43,PLCB1,TK2,REEP1,EMSY" Drug 7504_UP "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "CDC42BPA,NCOA1,ADGRB2,CA12,ARHGEF2,QKI,AKAP7,ABCG1,HDAC9,EDIL3,KAT8,ZNF589,DENND2A,SYT17,SLC2A6,INPP1,IPO5,NLE1,PPP5C,ZDHHC14,CLIP1,FNDC3A,SLC22A4,KDM4B,ELOVL4,SEPT8,VPS13A,SMG6,R3HDM1,TSC2,FAM155A,LMF1,ZBTB38,SEMA3B,PCBP4" Drug 5049_DN Indomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.10E-03 1.00E+00 2.50E-02 2.81E-01 35 195 "NME5,CHN2,TPP1,AKAP7,CSF1R,DBT,PARD6A,MBNL2,ING4,SPEG,B4GALNT1,GPR37,CNTRL,GUCY1B1,MEF2C,CNOT4,FA2H,ELOVL2,ZSCAN32,SUGCT,ATXN7,SCN8A,SH3BP2,DZIP1,BTBD7,PDZD2,POGZ,SS18,FBXW11,SYNE1,GPR161,BEX4,LMF1,SPHK2,EVI5" Drug CID004630073 AC1NDQQL Stitch 4.30E-03 1.00E+00 2.61E-02 2.94E-01 6 15 "CALCRL,POLL,PPP3CC,TACR1,CABIN1,NELFE" Drug CID005311375 "L-817,818" Stitch 4.30E-03 1.00E+00 2.61E-02 2.94E-01 6 15 "BOC,MCHR1,ABCB1,SST,SSTR1,SSTR2" Drug CID000007354 butyl methacrylate Stitch 4.30E-03 1.00E+00 2.61E-02 2.94E-01 6 15 "ADD1,BOC,F8,RNASE1,SAFB,TBL1X" Drug CID000031657 Vydate Stitch 4.30E-03 1.00E+00 2.61E-02 2.94E-01 6 15 "ACHE,BCHE,DDR1,FOLH1,HP,PLEC" Drug CID000005263 lysosphingomyelin Stitch 4.31E-03 1.00E+00 2.62E-02 2.95E-01 30 161 "CDR1,PLCXD3,ENPP6,GALC,GPR12,LPAR4,PLCD4,KCNJ5,KIT,ASPRV1,KITLG,MITF,P2RX7,ENPP2,PLCB2,PLCD1,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,FBXW7,RYR3,MAPK12,SMPD3,FNDC3A,PLCB1,TACR1,PLD4" Drug CID006102719 2gzl Stitch 4.34E-03 1.00E+00 2.64E-02 2.97E-01 12 46 "AMPH,CDR1,VCAN,CHRDL1,DNM1,DNM1L,HIPK3,GMPR2,MX1,PTPRN,GSTCD,DDN" Drug ctd:D003932 Heroin CTD 4.34E-03 1.00E+00 2.64E-02 2.97E-01 12 46 "AMPH,SYNGR3,PREPL,PDE4DIP,VTI1B,NTRK2,SLC25A23,SEPT4,SNAP25,STXBP1,SYT1,ENHO" Drug CID000023930 manganese Stitch 4.36E-03 1.00E+00 2.65E-02 2.99E-01 114 791 "METAP1D,ADCY5,ADCY6,ADCY8,BRAP,APOC1,APOC2,ATP2A2,ATP2B2,ALDH7A1,FUBP1,GYG2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CCK,KRIT1,RGN,CBFA2T2,ENTPD2,TIGD7,CACNA2D2,CHRNA4,B4GALT6,CNOT8,COL4A5,GAL3ST1,CPS1,ENTPD4,CSNK1E,CSNK1G3,DAPK3,B3GAT3,DNM1,DTNB,AASDH,IRAK4,CALCRL,TUBD1,ENO2,ERBB2,ERBB4,PIPOX,TUBA1B,PTK2B,TUBB3,FDFT1,PPP1R1B,FECH,FGF1,POLR1B,ATP2C1,FUT9,GABBR1,GCNT2,TUBA8,GHR,TTBK1,GLUL,POLL,GUCY1A1,GUCY1B1,HBA1,IDH3A,IDH3B,IL12A,INPP1,ITGA7,ITGAM,ITPKA,LAMA2,LIG4,MAP4,MBP,NBL1,NPR2,SLC11A2,P2RY1,PDE4B,PKD1,PKM,POLG,POLR2F,PPP3CA,PPP3CC,PPP5C,MAPK3,MAPK9,CNNM2,LAMA1,PTK2,NUDT11,NEK11,RYR3,GALNT10,FNDC3A,SLC11A1,SNCA,NMNAT2,ITPRID2,NUDT10,ACTR6,CABIN1,TUBB2A,TUBB1,UGT8,WRN,TUBA1A,GAL3ST3,MSRB3" Drug CID000096524 n-butyl carbamic acid methyl ester Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ABHD6,AMH,EDNRA,FGF1" Drug CID005311026 Bim23268 Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "MCHR1,SST,SSTR1,SSTR2" Drug CID000088290 4-mercapto-4-methylpentan-2-one Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "NFS1,KYAT1,CTH,PCYOX1" Drug CID000086079 Thfc Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "MBNL1,PRODH,CLSTN2,ADHFE1" Drug CID005321976 CID5321976 Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ACHE,CCK,SNAP25,TSN" Drug ctd:C040168 19-oxo-11-deoxycorticosterone acetate CTD 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "EDN1,EDNRA,EDNRB,MAPK3" Drug CID000068460 aureothricin Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "TAOK1,TAOK2,PTK2B,PTK2" Drug CID003080955 Mor-502 Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ARSE,CAPN3,GAA,UGT8" Drug CID000060714 gadoteridol Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "CASP8AP2,FICD,HNMT,TET1" Drug CID000032832 3-nitropropanol Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "AASS,GPD1,GPD2,ADHFE1" Drug CID000129517 MS-857 Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ALDH7A1,CALM1,KRIT1,PDE3A" Drug CID006102852 AC1O0V4Y Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "CASP8AP2,MRO,HNMT,TRIO" Drug CID005460582 nitroxide Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "CLTC,PAX6,SYNE1,ARHGAP9" Drug CID006449836 TZC-5665 Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ALDH7A1,CALM1,KRIT1,PDE3A" Drug DB01373 Calcium Drug Bank 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "CALM1,CAST,ATP2C1,S100B" Drug CID000012959 dimethyl phosphorodithioate Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "ACHE,BCHE,DMPK,PIK3C2A" Drug CID000092956 DPhP Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "DMPK,POLK,SCP2,TP53BP2" Drug CID000104788 gonyautoxin II Stitch 4.37E-03 1.00E+00 2.65E-02 2.99E-01 4 7 "CIT,KIT,TRERF1,ST8SIA2" Drug 1166_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.41E-03 1.00E+00 2.66E-02 3.00E-01 32 175 "NDRG2,TRMT9B,NCOA1,CFLAR,ST3GAL5,CD86,CREM,SIPA1L1,KIAA0753,SGSM2,FAM13A,MBNL2,OGA,LILRA2,NINJ2,PDE4B,PLCD1,PMP22,MBOAT7,PRKACB,PTPRN2,CEP97,HSPA4L,SNCA,RGL1,KIAA1107,SZT2,TK2,FLRT2,PARP11,PHTF2,FXR1" Drug 1057_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.41E-03 1.00E+00 2.66E-02 3.00E-01 32 175 "OSBPL1A,CDC42BPA,MADD,CAMK2G,ARMC8,GIT2,DBT,RCAN1,DTNA,DNAJB6,NOP56,ATP2C1,FYN,DIDO1,MUM1,HSF2,NFYA,STRN3,MBOAT7,KLK6,MORC4,HSPA4L,SGK1,SH3BGR,PPM1E,JMJD6,SYT1,TBL1X,UBE3A,LMF1,ZNF189,FXR1" Drug CID000133240 N-propanoylmannosamine Stitch 4.43E-03 1.00E+00 2.66E-02 3.00E-01 10 35 "ST3GAL5,ST3GAL6,ST6GALNAC3,CHL1,L1CAM,NCAM2,MAPK3,ST6GAL1,ST8SIA1,ST8SIA2" Drug CID000440311 beta-tyrosine Stitch 4.43E-03 1.00E+00 2.66E-02 3.00E-01 10 35 "C5,CSF1R,CSF2RA,EGFR,FGF1,FLT1,JAK2,KIT,MATN3,MAPK3" Drug ctd:D010672 Phenytoin CTD 4.43E-03 1.00E+00 2.66E-02 3.00E-01 62 392 "ACHE,CASKIN1,LTBP4,PARG,NCOA1,ADGRB3,PTBP2,ISPD,KYAT1,LDB2,KRIT1,SCARB1,LRBA,CDH2,ARMC8,ABCG1,SIPA1L1,VCAN,PHF14,EGR3,KCTD3,EMX2,SH3YL1,FGF12,PCYOX1,AGAP3,SMC2,ARFIP1,GLUL,ZNF638,PSIP1,HSPA1L,IGF1,IL6R,KCND2,KCNH2,LAMA2,NRCAM,ABCB1,PLCL1,PLEC,PLTP,MAPK3,PTCH1,KHDRBS2,RPE,FNDC3A,SLC4A3,RBM34,MESP1,KLHL7,SYPL1,ITGB3BP,TLR4,TP53BP2,FLRT2,XRCC4,ADAMTS9,AMN1,NLRP3,AAAS,SENP7" Drug 1280_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.66E-02 3.00E-01 33 182 "FAM131A,STX16,SLC25A14,CD86,CD38,CHN2,QKI,VCAN,SLITRK5,PPP1R16B,DOCK4,DBT,DTNA,FCF1,FAM13A,OGA,ARFIP1,TXNL4A,MEF2C,NFYA,SLC11A2,PDE4B,PDE4D,CCSER2,STRN3,PTK2,SLC12A2,NXT2,ANKRD12,FBXW11,FLRT2,ZNF45,NLRP3" Drug 3808_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.66E-02 3.00E-01 33 182 "ARRB2,ST3GAL5,CA12,CAMK2G,LHX2,ARHGAP32,TBC1D5,ABCC5,FAM13A,SCARA3,GPER1,SHISAL1,ITPKB,JAK2,ZNF862,SH3TC2,MAP6D1,FAM102A,ST6GAL1,ANKRD6,LIMS2,COA1,PDZD2,PHLDB1,TRIM2,GPR161,HEY1,CBX5,REEP1,MPPE1,PLSCR4,FZD3,PHTF2" Drug 6663_UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.66E-02 3.00E-01 33 182 "ADORA1,CDC14B,PDE8B,N4BP2L1,AZGP1,CFLAR,BMPR1B,IL33,HAP1,RUNX1T1,CREM,AKAP12,PDE4DIP,CTH,PYGO1,PITPNC1,STX2,ETV1,FGFR1,NSG1,PADI2,KCNN1,ADAM11,PFKFB4,SMOX,PMP22,SLA,RBM26,COBL,MCF2L,TBL1X,PRDM10,FAM13C" Drug 3887_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.44E-03 1.00E+00 2.66E-02 3.00E-01 33 182 "MAP4K3,ZBTB10,SYNJ1,ARHGEF7,PUM1,USP6NL,FBXL5,E2F5,RASGRP1,CHST15,SEC24B,KIF2A,NFE2L2,NFYA,CNOT4,PIK3R1,CCSER2,STRN3,PPM1B,QRICH1,REV3L,SETD5,ATXN7,SCAF8,CHD9,FBXO11,TMCC1,KDM3A,ZC3H4,FBXW11,PUM2,KAT6B,UBE3A" Drug 3072_UP Rolipram [61413-54-5]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 34 189 "AMPH,BIN1,KCNAB2,SEMA4G,PDE8B,DNAH17,CFAP410,CHN2,CREM,SIPA1L1,VCAN,PDE4DIP,TNK2,RASGRP2,NCALD,KCNMB4,GRIK5,VSIG4,KCND1,PCDH8,PDE4B,MASP1,RELN,PID1,GTDC1,NLGN1,SLC11A1,ZNF415,PDZD2,SEPT8,TNS2,TK2,R3HDM1,LMF1" Drug 6694_UP Loxapine succinate [27833-64-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 34 189 "ADCY6,APAF1,APC,GAS7,SLC4A4,SCAPER,CAPN3,CBS,TAOK2,QKI,PCYT1B,PDE4DIP,ECM2,HIPK3,SEMA3D,MBNL2,FER,CAMKK2,DISC1,SOX21,KITLG,NELL2,NF1,PDE4A,ZSCAN32,EMID1,SCN2B,OGDHL,ZC3H13,RPGRIP1L,AP4E1,ZNF24,REEP1,PRDM10" Drug 1307_UP Corticosterone [50-22-6]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 34 189 "ABHD6,APBB2,APC,BACH1,SYNJ1,C5,CD86,BAG4,CREM,VCAN,NR1D2,DMTF1,RCAN1,HIPK3,EGR3,ING4,ERAP1,COPS8,GLYR1,MSL3,MPP2,NF1,CNOT4,OGG1,PLCD1,MINDY2,PPM1B,SUPT20H,SPP1,SAMSN1,NXT2,DMXL2,MARCH8,UBE3B" Drug 5586_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 34 189 "ADORA2A,OSBPL1A,AMPD3,BIN1,BACH1,CA4,CBFA2T2,ABI3BP,NRG2,CPS1,PDE4DIP,SPOCK2,ELMO1,RCAN1,EDNRA,ING4,TNK2,SEPT9,GNAL,IL6R,KCNH2,KIFC3,AFDN,MYO7A,PCDH9,SERPINI1,PLXNB1,MAPK7,HSPA4L,SH3BGR,SOX15,PCDHGA10,TRPM2,VLDLR" Drug 3262_DN "Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 34 189 "GAS7,APOC1,CDK13,STX16,ADAM15,CFLAR,QKI,CSF1R,GREB1,DAPK3,RCAN1,FCF1,ING4,FER,FHL1,FAM49B,OGA,INPP5K,ZNF276,FERMT2,SPACA9,GSN,KITLG,CNOT4,PIK3R1,PLEC,RGS12,SLC25A36,EMID1,RASA3,SMARCD3,TRIM2,CABIN1,REEP1" Drug 6357_DN Condelphine [7633-69-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "BIN1,EP400,APLP1,APOC1,WHRN,HDAC9,GIT2,CNNM1,MRNIP,GPHN,EZH1,TRAF3IP2,DENND2A,ARFIP1,GNG4,GPER1,L1CAM,MAP4,MT1M,ZNF862,NLE1,PRPH,RAD51D,TRAPPC13,ASAP3,FUZ,PEX26,CDK5RAP2,DDN,CAMTA2,POGZ,ARHGEF9,SYN2,MPPE1,TIGD6" Drug 2560_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NDRG2,AGT,ADGRF5,DDO,AZGP1,CACNA1G,CA12,NCOR2,BRINP1,EGFR,AASS,ERBB2,DCTN2,FYB1,LYVE1,RUNDC3A,GLI2,PRUNE2,PCLO,GRIK5,HNMT,TJAP1,KCNJ5,MAPT,MSR1,OPRL1,PTPRG,EPN2,PKNOX2,SNCA,TACR1,WSCD1,SYNE1,ICAM5,TRO" Drug 6084_UP Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "LTBP4,ALK,BIN1,ARHGDIG,PLA2G4C,ATP2B2,CFAP410,ARHGEF2,SULT4A1,LY86,CNN3,CSF1,ARHGEF10,VCAN,RASSF2,BRINP1,SPEG,REEP2,FHL1,FYB1,RUNDC3A,GRIN2C,GSN,KHK,SAMD9,PTPRB,ZFP2,SH3BP2,ARHGEF40,SSTR2,ZEB1,FAM189A1,SLC30A3,PLSCR4,KAT6A" Drug 2935_DN Harpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABHD6,PPFIA4,ARRB1,CFLAR,MTMR3,SLC16A4,LHX2,CRY2,PDE4DIP,ECM2,RASGRP2,CD320,USP19,PCLO,MAN1B1,ELOVL5,SMAD1,GIT1,N6AMT1,NRCAM,PPP3CC,PTPRN2,ZNF493,RGS3,PLPPR3,SH3BGR,ANKRD6,TMCC1,KDM4B,JMJD6,VPS13A,AP4E1,TNS1,TPM1,GDPD5" Drug 6772_DN Piperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APC,EPB41L5,PPFIA3,BCL7A,SYNGR3,PLAA,QKI,NCOR1,MFAP3L,DTNA,VPS26C,FHL1,B4GALNT1,SRCAP,GFER,GRB10,KHK,MEIS1,LYRM9,NEK1,NFYA,CNOT4,RETREG1,RAD51D,SH3BP2,NXT2,TNS2,BEX4,PARD3,HIRA,WRN,EMSY,MFF,UBE3B,PHTF2" Drug 1338_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "CDK13,CFLAR,CAPN3,ARMC8,DBT,RHOBTB1,RCAN1,FEM1B,ZNF589,ANKFY1,PDLIM5,ERAP1,GLUL,HSF2,IL6R,ITGA7,JAK2,LIG4,LSS,LRP12,SAMD9,RGS3,FBXW7,DGLUCY,PEX26,LARP4,NXT2,WIPF1,LAT2,ZNF24,TFIP11,UPF3A,EMSY,NLRP3,RNF146" Drug 2670_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SYT13,PTCH2,ATP1A3,AZGP1,CRLF1,PICK1,HAPLN1,ARHGEF10,HS3ST2,DTNB,EDN1,EDN3,EDNRB,HSD17B14,OLFM1,GAD1,GNAO1,SPACA9,KCNQ3,MN1,NINJ2,PDE4D,PPARA,RGS4,RGS12,EMID1,ABLIM3,SLC11A1,BTBD7,PEG10,SMG6,RPGRIP1L,FAM189A1,TIMP4,ICAM5" Drug 7559_DN ST021200; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "RALGAPA1,NDRG3,ADCY6,BIN1,APC,APOC1,ALDH7A1,RIPK1,MTMR2,BAIAP3,CBS,KYAT1,MAMLD1,EDIL3,EDNRA,FCF1,EZH1,SCML2,BAIAP2,FHL1,DENND2A,INPP5K,SCIN,ITGA7,JAK2,NFYA,CNNM2,MAPK12,LIMS2,ELMO2,DDN,FBXW11,TCF4,DNAH7,MPPE1" Drug 341_DN sodium 4-phenylbutyrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "C1QTNF1,BIN1,ARNTL,CAMK2B,CREM,AATK,DNAH9,EDIL3,PLEKHA1,ZMYND10,FGFR1,FGFR3,FOLR2,SMC2,SRCAP,GPER1,DIDO1,SOX21,NXPH3,ADAM22,PCDH9,PDE1C,NLE1,PPP2R2B,RGS4,SAFB,RASA3,FUZ,SLC11A1,AGTPBP1,WSCD1,PARD3,TNS1,ZNF142,FIP1L1" Drug 5830_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,MTUS1,APC,ADAM15,TAOK2,WHRN,SNPH,DCAF8,ZNF337,SPOCK2,SGSM2,ACOT8,EDNRA,DCTN2,FAM49B,RNFT2,SLC2A6,RASSF8,INPP5B,KHK,LRP12,PRPH,SLC6A8,SMARCA4,SNCA,ZBTB43,DDN,TNS2,PARD3,CABIN1,HIRA,LMF1,ZNF23,MAP3K12,ST7" Drug 499_DN "novobiocin sodium, USP; Down 200; 100uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NDRG2,OGT,NCOA1,N4BP2L1,ATP6V0A1,RGS11,SLC25A14,MAP4K4,ARHGEF6,DAPK3,DRP2,DTNA,FEM1B,ERCC2,RASL10A,HPGDS,MAN1B1,SYNPO,MARK1,MATK,NLE1,PNMA3,MAPK7,NKAIN1,RNASE1,FAM192A,SNCA,TSNAXIP1,DBNDD2,CLASP2,ELOVL4,EXOC7,HIRA,GDPD5,MPPE1" Drug 5824_UP Meropenem [96036-03-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "C1QTNF1,SEMA7A,SEMA4G,CFLAR,CACNA1I,CAMK2B,ARHGEF2,FOXN3,CNOT8,QKI,PHF14,ARHGAP24,TRMO,KCNJ5,KIFC3,MAP2,TAGLN3,NPY,CDK18,BCAS3,SNRK,PTPRE,GSTCD,KIRREL1,NEK11,FBXW7,TCP11L1,FAM192A,SBF1,FNDC3A,TSNAXIP1,CEP68,KIAA1107,WIPF1,RNF146" Drug 6042_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SYN3,PLA2G4C,MARK4,ALDH7A1,CACNA2D1,WHRN,NCOR2,CNTNAP2,RUSC2,SRPK3,C3orf18,HSD17B14,VPS13B,GAD1,PCDH17,ITGA7,ITPKA,KIT,MTRF1L,NECAB2,MINDY2,PPP2R2B,GRAMD1C,SAMD9,FAT4,RGS12,RPS6KA2,PKNOX2,SMARCD3,ATP10B,TCF4,PCDHGA10,TLR4,TPM2,AMACR" Drug 5962_DN valinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADRB2,GAS7,ALDH7A1,KIF1A,SYNJ2,FOXN3,CHGB,TAOK2,PICK1,AKAP7,CRMP1,CSF1R,IPCEF1,HIPK3,CNNM1,MRNIP,FGFR1,GNAL,GPD2,HLF,SHISAL1,FAM69A,ADAM22,NDP,PRKAR1B,FBXW7,TCP11L1,CNKSR2,MCF2L,CRTC1,CHST8,TIAM1,OSBP2,TFIP11,KCNAB1" Drug 6707_DN Propofol [2078-54-8]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "OGT,PPFIA3,PDE8B,NRP2,ST3GAL5,ARHGEF7,MYRF,FOXN3,TAOK2,RAB28,WHRN,ENTPD4,CHRDL1,FCF1,IRAK4,COQ7,FGFR1,USP19,CNTRL,INPP5B,MAP4,SCAMP5,NF1,CNOT4,PDE4D,SH3TC2,FAT4,CCDC88A,KDM4C,CAMTA2,SS18,GPR161,TPM2,ZKSCAN5,PHTF2" Drug 2755_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "KCNAB2,APOC1,CDK10,ARNTL,SLC4A4,ATP6V0A1,KIF1A,SYNJ2,RUNX1T1,CACNA2D2,PLEKHB1,PPP6R2,SEMA4D,TRAF3IP2,SEPT9,ALDH1L1,SRCAP,GNG4,ICA1,KCNN1,ZNF862,NPTX1,NPTX2,PDE4A,PLXNB1,C1orf54,SLC6A8,SIRT2,ARHGAP26,TSPYL2,DMXL2,TK2,MAP3K12,DNALI1,GAN" Drug 3048_DN Propofol [2078-54-8]; Down 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "RALGAPA1,CDK13,MARK4,HIP1R,SLC16A4,CHRNA4,RAB33A,STOML1,NRG2,VCAN,PDE4DIP,ZNF337,DBT,PLXNC1,MRNIP,GCNT2,COPS8,ICA1,NPR2,PDE4A,PDE4D,SLC25A23,PPP3CC,ZCWPW1,RGS3,NEK11,ZNF821,SH3BGR,SH3BP2,MAPKBP1,TROVE2,KIAA1107,TCF4,ZNF225,ST7" Drug 4149_UP Dibucaine [85-79-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "RALGAPA1,AP2A2,AGT,MARK4,ATP2B2,CFLAR,SYNJ2,CACNA1I,RUNX1T1,USP2,AKAP7,DAPK1,DRP2,SNX29,CALCRL,ETV1,AGAP2,FAM49B,OGA,KCNB1,LIFR,NPR2,STRN3,PPP5C,SAMD9,GDPD2,RYR3,ST6GAL1,PKNOX2,RBM26,WIPF1,SLC30A3,SLC17A7,PHTF2,NLRP3" Drug 3530_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADD2,NME5,CDC42BPA,APBB2,APC,CFLAR,SCARB1,ARHGEF2,CACNA2D2,AKAP5,RIMS2,SEC14L5,DGKG,TMCC2,ING4,FHL1,RUNDC3A,GPD2,ICA1,SMAD1,MEF2C,ADAM22,PFKFB2,RIPOR1,RGS12,MRAS,FBXO11,SYBU,UNC5B,ARHGAP26,PLCB1,EXOC7,PCDHGB6,XRCC4,PARP11" Drug 3368_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SYN3,NDRG2,C1QTNF1,CACNA1I,KALRN,CBARP,TAOK2,COL9A3,DAPK3,KLHL3,EDN1,EGFR,PTK2B,ERAP1,DISC1,RUNDC3A,GNAO1,GPER1,GRIK5,HLF,MSR1,TAGLN3,NNAT,OPRL1,C19orf57,MAPK7,SAMD9,ZNF493,KDM4B,IZUMO4,DOCK9,FLRT2,LAT2,KCNAB1,PARP11" Drug 5418_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ALDH7A1,CFLAR,SYNJ2,PLEKHB1,RAB28,SH2B1,MFAP3L,ZNF589,DISC1,GPER1,ATXN2L,IL6ST,IPO5,MAP4,MBD1,MITF,RPS6KA2,SEC14L1,ASAP3,EPN2,BTBD7,COA1,LIMCH1,KIF13A,KDM4B,TTBK2,PLCB1,RPGRIP1L,TNS2,TMEM121,CHST8,HIRA,VLDLR,GDPD5,PHTF2" Drug 5857_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "BRAP,CASK,SLC4A4,SLC25A14,SPAG9,CCNT1,CDH2,CNOT8,DCAF8,DBN1,DBT,GPHN,ERCC2,ZNF589,FHL1,GAD1,DISC1,ARFIP1,PCLO,MAP4K5,AGFG1,FAM69A,INPP5B,MYO6,NCF2,SLC11A2,SUPT20H,ELMO2,LIMCH1,PEG10,NXT2,PARD3,ZNF32,URM1,ITM2C" Drug 4342_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ALK,BEGAIN,APOC1,CDC14B,CDK13,ZSCAN18,CFAP410,SCARB1,SYNGR3,ARMC8,SNCAIP,ARHGEF10,CNTNAP2,CYBB,DTNA,ELN,PRELID3A,RASSF8,IL6R,MAP4,TM6SF1,MT1M,PALM,CCDC40,TCP11L1,CXXC4,SP4,IQSEC2,DDN,LMO3,EXOC7,DMXL2,ZFPM2,THRA,NT5M" Drug 3331_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NME5,APBA2,APLP1,RASL11B,SLC4A4,N4BP2L1,BAIAP3,CFAP410,CRLF1,PICK1,GSDME,TMCC2,MTSS1L,ERCC2,SPEG,AGAP2,KHDRBS3,GNAO1,LILRA2,GRIK5,GRM8,TJAP1,ITGAM,MMP17,FXYD7,NF1,NOVA2,PDE4B,SAMD9,ZDHHC14,ST6GAL1,LIMCH1,KDM4B,CRTC1,VIPR2" Drug 6888_UP carmustine; Up 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,AK2,AMT,APOC1,BCAS1,MARK4,SLC2A11,RIPK1,SLC16A4,CNOT8,PICK1,BAG4,PHF14,RCAN1,DTNA,FCF1,STX2,ANKFY1,CGREF1,RUNDC3A,GLYR1,CACFD1,LSS,ADAM22,ZNF862,PDPK1,RGS12,TCP11L1,ZFP30,SH3BP2,COA1,FBXW11,DMXL2,LMF1,MPPE1" Drug 6007_DN Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APBA2,APBB2,APLP1,BCAS1,SLC2A11,KIF1A,SYNJ2,SCAPER,LDLRAD4,AP4M1,UBE2L6,QKI,CNTNAP2,ZNF589,FAM49B,SRCAP,MALT1,HSF2,JAK2,MMP16,NF1,CNOT4,SAMD9,ANKRD6,CXXC4,SNCA,KDM4B,CDK19,MCF2L,TK2,ZKSCAN5,PLPPR2,VIPR2,EMSY,KCNAB1" Drug 2102_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "RALGAPA1,ALK,DOC2A,APOC1,BCL7A,ST3GAL5,LARGE1,ARHGAP22,ABCG2,QKI,CSF1R,ARHGEF4,MFAP3L,HS3ST2,ZNF44,SPIN1,KCNMB4,SPACA9,RASSF8,SHISAL1,IL6ST,PTPRH,GAL3ST4,RGS4,KIRREL1,SLC9A5,CLASP2,TTBK2,TRIM2,HIF3A,TIAM1,EVI5,SLC17A7,PHTF2,DPF3" Drug 2390_DN "Glutethimide, para-amino [125-84-8]; Down 200; 17.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ALK,DOC2A,AMT,SYNJ2,CAPN3,CCNT1,CD86,ZNF337,KIAA0753,ANKMY1,FCGRT,ZNF589,FHL1,OGA,FYB1,ALDH1L1,SRCAP,SPIN1,LILRA2,ITPKB,NFYA,CNOT4,FAM184A,SH3BP2,KBTBD4,ARHGAP26,ZC4H2,TCF4,HIF3A,PIK3R5,HIRA,XRCC4,ZNF32,UPF3A,PHTF2" Drug 960_DN 5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASPHD1,ADCY6,AMPD2,CDC42BPA,NCOA1,MPDZ,AKAP7,KIAA0586,SUGP2,EGR3,CGREF1,GHR,GPER1,RNFT2,MIA2,MMP16,MPP2,GIT1,ADAM22,MYO9A,SLC11A2,PLEC,PLXNB1,WDR25,SYBU,ABLIM3,EPN2,LHPP,CLSTN2,DIP2A,EXOC7,AP4E1,TRIO,PCBP4,PHTF2" Drug 3705_UP Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "LTBP4,CDC14B,RASL11B,ADAM23,NRP2,P2RX6,TAOK2,EPS15L1,HOMER3,CNTFR,CSF1,IPCEF1,NCALD,ST3GAL6,NSG1,SRCAP,GNAL,GNAO1,GRM2,ICA1,TJAP1,IL6ST,AFDN,MMP16,ADAM22,NNAT,PRKAR1B,PTH1R,MAPK12,FUZ,SLC11A1,DOCK9,SLC44A1,ICAM5,REEP1" Drug 5411_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABHD6,APC,EPB41L5,CDC14B,CDK13,KYAT1,SCARB1,ARHGEF2,QKI,NCOR1,ZNF804A,MFAP3L,MED12,CNNM1,CELSR3,MBNL2,EIF5,FGFR1,CINP,GCNT2,MSL3,LSS,MATK,MIA2,SETD4,RGS12,PLCB1,CRTC1,PCDHA6,AP4E1,CABIN1,REEP1,GDPD5,HPS4,SMIM8" Drug 3568_DN Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,APBB2,APC,PPFIA3,MARK4,CFLAR,CA12,ENTPD4,SH2B1,PPP6R2,DTNA,EGR3,ANKFY1,TPK1,PRELID3A,AHDC1,USP19,CNTRL,BTN2A1,KHK,ADAM22,CNOT4,PDE4A,RETREG1,PRKAR1B,AMBRA1,SOX3,POGZ,EXOC7,IQCE,TRIM2,CRTC1,TMEM121,AP4E1,TPM1" Drug 3387_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "FZD9,NME5,GAS7,LDLRAD4,CA12,FRY,ERCC2,CAMKK2,ICA1,JAK2,KCNH2,LAMA2,MEF2C,MSR1,TAGLN3,NF1,NPTX2,PCDHGC3,PDE4B,CEP41,CARF,SH3GL3,FNDC3A,CXXC4,PEG10,ARHGAP26,ATP10B,HEY1,PARD3,PIK3R5,UBE3A,FLRT2,ZBTB14,PHTF2,SENP7" Drug 2510_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADD2,AGT,PPP4R4,PDE8B,LDLRAD4,CALB2,HIP1R,EPS15L1,CABP1,NRG2,CREM,DGKG,DTNB,PLXNC1,COQ7,DLC1,SIGLEC8,GFER,KCNMB4,GSN,GUCY1A1,KCNF1,KCNN1,CNOT4,MTRF1L,MAPK10,RIPOR1,BEND5,ASAP3,PKNOX2,LIMCH1,SYP,UBE3A,LMF1,WNT7A" Drug 4208_DN Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APC,LGR5,MTMR2,LHX2,CLCN3,RGS6,CHRDL1,MBNL2,MTSS1L,SEMA4D,FYB1,ZNF44,SEPT9,AHDC1,GPD2,GRM8,SOX21,KPNA5,PACRG,RETREG1,PTPRB,RGS4,ATXN7,FRMPD1,PPP4R3A,KANSL3,MYH15,SPATA7,TRIM2,CABIN1,TRIO,RUNDC3B,VIPR2,ZNF711,EVI5" Drug 3248_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "FAM131A,APOC1,MPDZ,SYNJ2,SCAPER,B4GALT6,PLAA,ZNF589,ATP2C1,TXNL4A,POLL,GPR37,TJAP1,ITPKB,IPO5,TM6SF1,NPTX1,SLC11A2,PLEC,PLXNB1,POLG,FAM184A,GTDC1,RGS12,SBF1,SH3BGR,ZHX3,GLT8D1,TSPYL2,NSFL1C,MTCL1,TIAM1,WIPF1,ZNF74,SEMA3B" Drug 2383_DN Norethindrone [68-22-4]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NCOA1,SCAPER,LDLRAD4,CAPN3,CAST,RAB28,CPS1,COQ7,ZNF589,ERAP1,SEPT9,ALDH1L1,COPS8,ELOVL5,TJAP1,INPP5B,ITGA7,KIF2A,MAP4,MIA2,MYO9A,CNOT4,PDE4A,ZNF426,TRHDE,DCUN1D2,TCP11L1,RPS6KA2,SH3BP2,FBXO11,ZNF667,DDN,EXOC7,KAT6B,TPM1" Drug 4281_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "C1QTNF3,PPFIA4,GAS7,MARK4,N4BP2L1,ADGRB2,ADGRB3,NRP2,KSR1,FUBP1,CACNA1I,TPP1,HOMER3,VCAN,PDE4DIP,LRRC17,F5,IQGAP2,USP19,RUNDC3A,GPR37,BTN2A1,MARK1,ADAM22,NPTX1,PCBP3,ELOVL2,KCTD17,ZFP2,SLC4A3,KDM4B,DDN,AP4E1,TIMP4,ZNF24" Drug 631_DN benserazide hydrochloride; Down 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ARRB2,ADAM15,AZGP1,NRP2,CACNA1I,CBFA2T2,ARHGAP33,CRMP1,DAPK3,DNAJB6,FAM13A,DCTN4,FGFR1,SPIN1,DIDO1,BTN2A1,STMN1,MAP4,NF1,POLG,FSD1,PPP3CA,MAPK7,RBBP6,MSANTD2,KDM4C,TEX2,PHLDB1,FRYL,CHST5,TRIO,TSN,UBE3A,UBTF,KLC2" Drug 4802_DN Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "BIN1,APBB2,APC,PLA2G4C,NCOA1,BCL7A,MTMR3,MTMR2,ARHGAP33,ABCG1,CSNK1E,GIT2,SGSM2,DTNA,FEM1B,CNNM1,TPK1,STON1,DHX35,INPP5B,LYRM9,PRKAB2,SH3BP2,SMARCA4,KDM4B,CAMTA2,PCDHGA10,TMEM121,CHST8,SLC44A1,THRA,TPM1,ZKSCAN5,EVI5,GDPD5" Drug 4974_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASPHD1,NDRG2,AP2A2,APBA2,MARK4,SYNJ2,CFAP410,ARHGAP33,SULT4A1,HOMER3,CNTN1,CPS1,PHF14,RIMS2,SEC14L5,EXOG,DMPK,ING4,ACSL4,STON1,GRM8,KCNH2,MAP4,RETREG1,ZSCAN32,ZNF493,ZFHX4,COA1,LIMCH1,PHLDB1,TNS2,TRIO,HIRA,CLDND1,SPHK2" Drug 5261_DN Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,NME5,SEMA6A,APBA2,PLA2G4C,ATP6V0A1,BCL7A,SYNJ1,HIP1R,TOM1,MBNL2,EZH1,FGFR1,OGA,GNG4,GPER1,CACFD1,RNFT2,PADI2,MAP4,MBD1,NF1,LRP12,MBOAT7,FA2H,FSD1,FUZ,LIMCH1,ARHGEF9,TNS2,BHLHB9,VLDLR,EVI5,UBE3B,PHTF2" Drug 6766_DN Dipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,FAM131A,PPFIA3,PLA2G4C,CDK13,KIF1A,PTBP2,MAGI1,SLIT2,RAB28,AKAP12,DZIP3,GIT2,MFAP3L,SGSM2,DTNA,EDNRA,FGFR1,ATP2C1,CGREF1,INPP5K,KHK,LIG4,NNAT,CNOT4,SMIM7,TRAPPC13,SBF1,SMARCC2,ARHGAP26,PHLDB1,KAT6B,HIRA,LMF1,ACTR3B" Drug 2717_UP Ebselen [60940-34-3]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADD2,BIN1,MPDZ,CFAP410,CACNA2D1,CDO1,RAB26,SIPA1L1,RIMS2,DBT,MFAP3L,MAMLD1,RASGRP2,FGFR1,PRELID3A,GALC,AP4S1,BACH2,MPP2,MSR1,MX1,OGG1,OXTR,CEP41,GAL3ST4,RNASE1,PKNOX2,LIMCH1,SYT5,DNMBP,IQCE,TCF4,DNAH7,BEX4,ST7" Drug 7228_DN Praziquantel [55268-74-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASPHD1,APC,BCAS1,SYNJ2,CCNT1,ARHGEF2,QKI,ARHGEF6,AKAP12,FAM169A,DZIP3,ZNF337,KIAA0586,GIT2,DBN1,DBT,SGSM2,INPP5B,MEIS1,MIA2,SMIM7,PTPN13,RGS3,CCDC25,SBF1,ZKSCAN3,PDZRN3,CAMTA2,ITPRID2,VPS13A,IQCE,BEX4,CABIN1,KLC2,REEP1" Drug 4083_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "RALGAPA1,BIN1,CDC42BPA,APBB2,ARRB2,KIF1A,ST3GAL5,SYNJ2,STOML1,WHRN,SLC4A8,NCOR2,SLITRK5,LYPD1,FGF1,POLR1B,GLYR1,PCLO,PDE1C,PIK3R1,RETREG1,NLE1,PRKAR1B,GRAMD1C,SH3TC2,SH3BP2,PPP4R3A,LHPP,CEP68,ASTN2,GPR161,TIAM1,TMPO,TNS1,LAT2" Drug 1728_UP DO 897/99; Up 200; 8.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "C1QTNF3,BMP7,CAST,ABCG2,AKAP7,SEC31B,CSF1R,ARHGAP32,DBT,KIAA0753,DPH1,RASGRP2,SEMA4D,NSG1,ALDH1L1,KCNH2,KCNN1,CNOT4,NTRK3,PALM,PFKFB2,SMOX,MBOAT7,DEF8,C12orf49,ATXN2,SH3BP2,TMCC1,KDM4B,SYT1,TK2,SSBP2,NPDC1,URM1,RNF170" Drug 4473_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "DOC2A,CDK10,CASK,MARK4,ADGRB2,CFLAR,MYRF,ARHGAP33,HAPLN1,ABCG1,VCAN,CNTNAP2,DBT,COQ7,FGF1,PDLIM5,FAM49B,SEPT9,GLYR1,SHISAL1,KCNJ5,LSS,LYRM9,PIK3R1,KLK6,PID1,GAL3ST4,TROVE2,NXT2,ASTN2,SZT2,SLC44A1,TPM2,PHTF2,AAAS" Drug 5799_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AGT,GAS7,RASL11B,KIF1A,ADGRB2,CACNA1I,SCARB1,CHN2,CRMP1,ARHGEF4,DTNA,ING4,EPHB1,PDLIM5,PRELID3A,FYB1,NEU3,GNAO1,GNG4,SPACA9,PCBP3,POU6F1,ZSCAN2,C1orf54,RGS12,TCP11L1,OGDHL,KIF13A,ZSWIM8,MCF2L,KIAA1107,TCF4,SZT2,DOCK9,BHLHB9" Drug 3255_DN Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APLP1,CDC14B,CFLAR,SYNJ2,SCAPER,SLC4A8,CRY2,PDE4DIP,GREB1,USP6NL,IRAK4,ZNF589,FGFR1,OGA,SEPT9,SRCAP,FERMT2,TJAP1,MBD1,TM6SF1,MITF,MPP2,ADAM22,CNOT4,WDR25,ELOVL2,FAM184A,SLC25A36,SH3BP2,EXOC7,KIAA0930,TNS2,TMEM121,BHLHB9,SEMA3B" Drug 6637_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASIC1,AP2A2,KIF1A,CACNA1A,TAOK2,AKAP7,CSF1,PDE4DIP,EDIL3,TNK2,HSD17B14,MTSS1L,DENND4A,EZH1,PDLIM5,FYN,ZNF44,GPD2,GPR37,GRM8,IDH3A,IL6ST,CNNM2,PTN,ZNF821,ANKRD6,LIMS2,DDN,TROVE2,PDLIM2,TK2,WIPF1,EMSY,EVI5,PHTF2" Drug 425_DN staurosporine; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NDRG2,BEGAIN,APAF1,STX16,CFLAR,HAP1,CNTFR,RASGRP1,EPB41L2,TAOK3,FGFR1,FGFR3,AMOTL2,TRMO,POMT1,NEU3,GHR,MCHR1,PTPRT,SCIN,KHK,MAN2A2,MAPT,MBD1,MYO6,CCSER2,RGS12,ZNF821,PPM1E,SNCA,NMNAT2,GLT8D1,SS18,PLCB1,NDRG4" Drug 3923_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "BEGAIN,TRMT9B,BIN1,CACNA1I,CACNA1G,CFAP410,KALRN,RUNX1T1,CD86,CHN2,RAB33A,VCAN,DOCK2,TNK2,FGF1,FGFR1,FHL1,IGF1,KCNB1,MID1,NTRK2,NTRK3,PRKCB,ENOX1,ST6GAL1,PKNOX2,NMNAT2,CDK19,SYN2,TAL1,HIF3A,CHST5,TRO,VSNL1,KCNAB1" Drug 7143_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SLC4A4,SCARB1,B4GALT6,ARHGEF10,HDAC4,KIAA0753,ACOT8,SUGP2,STX2,VPS26C,FGFR1,MPP6,GLYR1,FAM69A,CNOT4,PIK3R1,ING3,ELOVL2,ROGDI,KIRREL1,FAM102A,WDR37,ARFGAP1,ZNF415,ZHX3,CEP68,TTBK2,SIN3B,TRIM2,TK2,UBE3A,LMF1,ZNF45,HPS4,KAT6A" Drug 1344_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "MADD,NCOA1,ST3GAL5,ARHGAP33,STOML1,CLTB,DCTN1,TNK2,ERCC2,FGFR1,SEPT9,CLASRP,SLC2A6,MAP4,SLC11A2,RIPOR1,ZCWPW1,ZDHHC14,PLPPR3,DHX30,ARFGAP1,SMARCC2,MYH15,MAPKBP1,KDM4B,IZUMO4,PBLD,STX1A,SYN2,TBL1X,OBSL1,CRTC1,CBX5,TNS1,CLIP2" Drug 6648_DN "Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "MTUS1,APC,CFLAR,EPS15L1,HAPLN1,ABCG1,DBT,SPATA2,PARD6A,TENM1,DENND4A,ETV1,FGFR1,TRMO,GAD1,STON1,GRM8,HLF,DHX35,TJAP1,NF1,PCDH9,LRP12,CNNM2,GSTCD,ZNF671,AMBRA1,LHPP,TROVE2,JMJD6,SYT1,ZEB1,ZNF34,XRCC4,AAAS" Drug 253_UP cox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADORA1,BIN1,ARNTL,DNAH17,NRP2,CAMK2A,ASIC3,SH2B1,NCOR2,DYNC1I1,ING4,C3orf18,CYP46A1,GLI2,GNAL,GNAO1,GRM2,GRM8,FAM107A,IGF1,L1CAM,LAMA2,PNMA3,C19orf57,RIPOR1,PNMA8A,FAM192A,ABLIM3,CXXC4,SNCA,IZUMO4,SPTB,TEK,TNS1,LMF1" Drug 2770_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABHD6,FAM131A,ARHGDIG,CA12,CCNT1,FAM189A2,COQ7,BAIAP2,ALDH1L1,HTATSF1,CACFD1,INPP5B,IPO5,MMP16,PCDH9,PDE4A,SLC25A23,FSD1,MAPK7,TCP11L1,CCDC92,SLC6A8,SLC22A4,KDM4B,SOX3,CDK19,ELOVL4,CEP68,STX1A,AP4E1,KLC2,KCNK12,GDPD5,MPPE1,GAN" Drug 2098_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASIC1,AQP6,ADGRB2,NRP2,ARHGEF2,ARHGAP22,CPNE6,AKAP7,DBT,RGS17,ZNF589,FGF1,SEMA4D,SIGLEC8,NEU3,TDRKH,ADAMTS13,ELOVL5,MMP16,NEK1,PDE4D,SUGCT,SLC4A3,ZHX3,UNC5B,ZBTB43,LHPP,ELOVL4,SYNE1,DNAH7,TRO,LAT2,MAP3K12,SLC17A7,PLSCR4" Drug 1399_UP Isoniazid [54-85-3]; Up 200; 29.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NDRG2,PKP4,APAF1,KRIT1,ARHGEF2,CLCN3,SOCS5,TBC1D5,CELSR3,PDLIM5,ATP2C1,KTN1,MAP4,MBNL1,NELL2,ENPP2,RETREG1,PLCD1,ZNF426,PPM1B,PTX3,MSANTD2,ATXN7,CCDC88A,TSPYL2,TROVE2,ITPRID2,LARP4,TACC1,AGTPBP1,FBXW11,TSC2,PLPPR2,EVI5,AAAS" Drug 313_DN NU1025; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AMPH,KCNAB2,ADGRB2,RUNX1T1,RAB33A,RAB28,ARHGEF6,KLHL3,DTNB,EDNRA,OPTN,AMOTL2,RASL10A,TRAF3IP2,PTPRT,VSIG4,KIFC3,NOVA1,ELOVL2,PTPRD,RGS4,ANKRD6,SLC2A5,PPP4R3A,SLC8A1,CDK5RAP2,HECW1,PEG10,SPART,SSTR2,ZC4H2,ELOVL4,SYP,TEK,NPL" Drug 2344_DN Salbutamol [18559-94-9]; Down 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASIC1,ARNTL,BCL7A,SCAPER,CAST,SPAG9,SCARB1,SOCS6,OSBPL3,CSNK1G3,CTH,NR1D2,FEM1B,FRY,PCOLCE2,FGFR1,COPS8,IFI16,KIF2A,MAN2A2,MAP4,MATK,RETREG1,LRP12,ZDHHC14,SMARCA4,DDN,VPS13A,FBXW11,THRA,PARD3,HIRA,ATP6V0E2,FTSJ1,ACTR3B" Drug 1686_DN Acetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,CDC42BPA,ARRB1,CFLAR,HOMER3,DCAF8,GIT2,SUGP2,SCML2,MPP6,SEPT9,RAB40B,PRRC2B,GSN,IL6ST,MAP4,MAPT,MIA2,MITF,NPR2,PTK2,SH3BP2,FBXO11,EPN2,FNBP1,TROVE2,CEP68,IQCE,SIN3B,TNS2,BEX4,HIRA,SEMA3B,MPPE1,ST7" Drug 6846_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABHD6,ALCAM,DOC2A,BIN1,MARK4,CFAP410,CACNA2D2,SRSF11,ASIC3,TAOK2,CSF1R,GREB1,RIMS2,SLC12A6,EDNRA,HIPK3,FHL1,IQCG,INPP5K,POLL,GNG4,ITPKB,KCNH2,NF1,PCDH9,FSD1,MINDY2,PRODH,RELN,SLC9A5,MAPKBP1,TSPYL2,CRTC1,TK2,UBE3A" Drug 7512_UP CP-863187 [668981-07-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "LTBP4,KCNAB2,GAS7,SHROOM2,CDC14B,DNAH17,CFAP410,CA12,STOML1,PHF14,HEPH,EDIL3,FGFR1,SCARA3,TRAF3IP2,GALC,NXPH3,ITGA7,KCNJ5,MAPT,ZNF862,SLC11A2,PDE4A,PFKFB2,PIK3R1,PPP5C,PRKAR1B,MAPK7,CCDC40,ZDHHC14,AMBRA1,CLSTN2,TIAM1,VIPR2,WIPF1" Drug 3251_DN Carisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "KCNAB2,APLP1,FAM131A,APOC1,CDK10,ARRB1,MARK4,CA4,CSNK1E,PPP6R2,TBC1D5,GIT2,TNK2,HSD17B14,PDLIM5,SEPT9,AHDC1,GSN,MUM1,KCNF1,KIF2A,LSS,MAP4,ADAM22,NPTX1,PLEC,PLXNB1,TMEM104,TMEM231,RPS6KA2,ARFGAP1,LHPP,CEP68,REEP1,SEMA3B" Drug 5877_DN Azaperone [1649-18-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABHD6,ADD2,EP400,MADD,MARK4,SLC4A4,CFLAR,C5,ZMYM4,LARGE1,CSF1,DZIP3,TM9SF4,SGSM2,COQ7,BAIAP2,ZNF276,GPER1,MAPT,SCAMP5,PDPK1,TMEM104,FAM102A,SLC6A8,TMCC1,KDM4C,TTBK2,SYT1,IQCE,WSCD1,TCF4,TNS2,ZNF34,NAV3,ST7" Drug 1113_DN doxycycline; Down 200; 14.4uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "OSBPL1A,CDK13,EIF4G3,MPDZ,SYNJ1,CCNT1,SYNGR3,HINFP,APPL1,ZNF337,TM9SF4,KIAA0586,DBT,ZBTB24,DMTF1,SEZ6L2,BTN2A1,MARK3,MKLN1,CCSER2,SMIM7,ING3,ZDHHC4,RGS3,KBTBD4,MYCBP2,SS18,NXT2,DIP2A,TBL1X,UBE2H,UBTF,MTCH1,WRN,SMIM8" Drug 1001_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AP2A2,AK2,ATP6V0A1,SRSF11,B4GALT6,TAOK2,EPS15L1,HOMER3,FEM1B,EIF5,KAT8,FGFR3,NOP56,GRB10,MUM1,KHK,NEK1,OGG1,CCSER2,LRP12,FSD1,C1orf109,PPM1E,SYBU,EPN2,SPTAN1,STXBP1,JMJD6,VPS13A,MCF2L,EXOC7,PDLIM2,IQCE,PARD3,FTSJ1" Drug 1929_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APLP1,NCOA1,SLC25A14,CDH2,CLCN3,PICK1,SNPH,KIAA0586,KLHL3,DTNA,TNK2,FCGRT,FHL1,CAMKK2,GAD1,CNTRL,CACFD1,SLC2A6,SCAMP5,RETREG1,RGS3,GSTCD,ATXN2,SEC14L1,ZNF821,GALNT10,TRA2B,CDK5RAP2,FNBP1,PHLDB1,WSCD1,CRTC1,NACC2,PLPPR2,MPPE1" Drug 5103_DN Sulindac [38194-50-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NME5,MARCH3,MARK4,ATP1A3,ADGRB2,FUBP1,CACNA1A,ARHGEF1,TAOK2,RAB28,SLC4A8,SNPH,ARHGAP24,SPOCK3,CNNM1,ETV1,ST3GAL6,SEMA4D,POLL,TDRKH,BACH2,JAK2,MAPT,TM6SF1,TAGLN3,NPR2,P2RY1,SLC25A23,CNNM2,BCAS3,WDR25,MYH15,WSCD1,ZNF225,EVI5" Drug 7330_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,APAF1,KIF1A,CFLAR,SCAPER,USP2,B4GALT6,HOMER3,CSF1,FAM169A,TBC1D5,BRINP1,JAKMIP2,MFAP3L,DUSP9,RRAGB,EZH1,FAM49B,PRELID3A,ZNF44,TXNL4A,CACFD1,ADAM11,NF1,CNOT4,MTRF1L,PPP5C,RIPOR1,GTDC1,KCTD17,ERC1,SPTAN1,PCDHGB6,R3HDM1,TFIP11" Drug 5499_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SRPX,RIPK1,KIF1A,KYAT1,AP4M1,BAG4,CREM,PDE4DIP,RCAN1,DTNA,SUGP2,COQ7,STX2,FHL1,TRMO,CINP,FAM49B,INPP5K,FERMT2,ICA1,KHK,NF1,NTRK2,CCSER2,SLC25A23,MAPKBP1,NXT2,PHLDB1,ZNF34,CABIN1,CDK20,NPL,XRCC4,KAT6A,SMIM8" Drug 5486_UP Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADRA1D,NME5,SEMA4G,ARRB2,ALDH7A1,CALB2,RCBTB2,AATK,CSF1,EDN1,C3orf18,RASGRP2,BAIAP2,RUNDC3A,DHX35,KCNB1,KCNJ5,MID1,NTRK2,ENPP2,FAM184A,ZNF493,ZDHHC14,ZNF821,SH3GL3,PEG10,CLSTN2,TK2,RUNDC3B,VIPR2,ZNF24,SPHK2,EMSY,EVI5,MPPE1" Drug 4381_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,SRPX,LTBP4,ALK,BIN1,PPP4R4,PDE8B,DNAH17,SGCE,CACNA1I,CFAP410,SOCS6,SLIT2,AKAP7,EDNRA,FGFR3,KHDRBS3,TMEM8B,GRIK5,MID1,ADAM22,NNAT,PDE4B,PRKAR1B,ELOVL2,CCDC40,ZMAT4,KCTD17,RPS6KA2,SNCA,TSNAXIP1,DOCK9,PARD3,UBE3A,KAT6A" Drug 2019_DN Edrophonium chloride [116-38-1]; Down 200; 19.8uM; HL60; HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADRB2,KRIT1,RCBTB2,EPS15L1,QKI,PREPL,RUBCN,DCAF8,TBC1D5,MAML1,DBT,DMTF1,DTNA,FEM1B,PHF20L1,DENND4A,ZNF44,PRRC2B,DIDO1,NFE2L2,SETD4,TRHDE,POLG,PEX26,CCDC88A,SMARCC2,ERBIN,SYPL1,TACC1,MCF2L,EXOC7,AGTPBP1,CBX5,TSC1,HIRA" Drug 2315_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AMPD3,CDC42BPA,APOC1,CDK13,MARK4,SLC2A11,BMP7,SYNJ1,RAB28,QKI,SH2B1,RCAN1,MBNL2,ZNF589,EFCAB2,SEPT9,BTN2A1,DHX35,ITPKB,KCNN2,TM6SF1,RETREG1,PPP5C,ELOVL2,TCP11L1,SH3BP2,BTBD7,MAPKBP1,KIF13A,ST5,PLCB1,LMF1,REEP1,TFIP11,EMSY" Drug 1684_UP "Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,EP400,CAMK2G,MAGI1,QKI,BAG4,SH2B1,RNF14,GREB1,DCAF8,TBC1D5,DBT,E2F5,ZNF589,FECH,BAIAP2,ERAP1,GLYR1,MUM1,INPP5B,MBD1,ZNF862,NF1,WDR25,ELOVL2,FBXO11,PPP4R3A,SMARCD3,CDK19,CEP68,TBCEL,TRIM2,TK2,ZKSCAN5,NDRG4" Drug 1146_DN "ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APC,N4BP2L1,ADAM23,SOCS6,SEC31B,RNF14,CSF1R,RHOBTB1,NR1D2,FCF1,ING4,CINP,LILRA2,MUM1,HNMT,ICA1,TM6SF1,NFYA,ZNF426,SAMD9,ZSCAN32,RNASEL,AMBRA1,ARHGEF40,ARFGAP1,SMARCC2,MAPKBP1,TMCC1,PBLD,CAMTA2,EXOC7,THRA,ZNF32,EVI5,URM1" Drug 5318_UP Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASPHD1,ABHD6,LTBP4,APOC1,BCAS1,ARRB2,ATP6V0A1,MTMR3,HIP1R,USP2,PDE4DIP,GREB1,EGR3,NCALD,FGFR3,DIDO1,ITPKB,JAK2,KCNN1,KHK,LSS,MATK,MX1,NF1,LRP12,PPP5C,CNNM2,ZSCAN32,SYBU,ZHX3,NXT2,DNMBP,PDLIM2,FAM155A,LMF1" Drug 6238_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "OGT,C5,SCARB1,TAOK2,RAB26,CREM,SOCS5,GREB1,DCAF8,SGSM2,RCAN1,MAMLD1,CELSR3,SEMA4D,DISC1,INPP5K,GHR,MAP4K5,HSF2,PMP22,RETREG2,POLG,ROBO1,AMBRA1,KDM4B,SOX3,CLASP2,SIN3B,TIAM1,KAT6B,VAV1,XRCC4,NDRG4,UPF3A,GDPD5" Drug 7382_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "CDC42BPA,SYNJ2,CA12,CCNT1,CLCN3,BAG4,CSNK1E,PPP6R2,EDNRA,F8,AMOTL2,SCARA3,CINP,CAMKK2,SYNPO,SMAD1,SLC11A2,SETD4,LRP12,MAPK7,KIRREL1,AMBRA1,PEX26,ELMO2,TMCC1,FNBP1,NMNAT2,ELOVL4,SUPT5H,EXOC7,TCF4,PARD3,UGT8,ZNF189,SH3GLB2" Drug 3472_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,C1QTNF3,APAF1,SEMA4G,RASL11B,SLC4A4,ATP2A2,CFLAR,CACNA1I,CAMK2G,SLC4A8,ENTPD4,GREB1,ARHGEF4,RUSC2,C2CD2L,VPS13B,VPS26C,SEPT9,SRCAP,IL6ST,KCNH2,SETD4,SMARCD3,SPTAN1,CDK19,ZBTB43,POGZ,DIP2A,EXOC7,ZEB1,UBE3A,WIPF1,REEP1,PCBP4" Drug 2179_DN Graveoline [485-61-0]; Down 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADRA1D,APOC1,ARRB1,SGCE,KYAT1,SLC16A4,LARGE1,SOCS6,CSF1,PDE4DIP,DGKG,TNK2,FHL1,ANKFY1,MSL3,LILRA2,GRIK5,PADI2,CNOT4,PLCB2,MINDY2,RIPOR1,ZNF493,ZNF671,RXRA,SNCA,KDM4B,THSD1,PDLIM2,LMF1,ZNF142,REEP1,ZNF225,MPPE1,ST7" Drug 4370_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AGT,BIN1,CDC42BPA,APC,GAS7,APOC1,ARHGEF2,CLTB,SULT4A1,REEP2,FHL1,CSPG5,GABRG2,GNAO1,GRIN2C,KCNJ5,AFF1,TAGLN3,NPR2,OGG1,P2RX7,PCDHGC3,PCSK1,PLCB2,STRN3,RFX2,STUM,SLC2A5,SLC11A1,MYO16,PLCB1,DICER1,UCHL1,LAT2,EVI5" Drug 1276_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "FAM131A,CDK10,SLC4A4,AP4M1,VCAN,DBT,FCF1,SUGP2,PLXNC1,EIF5,COQ7,CDKL3,TRAF3IP2,SEPT9,ADAM28,MSL3,CACFD1,JAK2,N6AMT1,NEFH,NNAT,PDE4B,NECAB2,MAPK3,RGS12,ZNF671,SEC14L1,ZNF667,TMCC1,KANK1,IQCE,LAMP5,HPS4,EPM2A,UBE3B" Drug 1770_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "PDE8B,SLC4A4,ADGRB2,MYRF,CA12,CACNA1A,CALB2,SPAG9,CHN2,CNTFR,AKAP6,TMCC2,TRMO,SPACA9,CACFD1,KCNF1,LAMA2,MBP,GIT1,DUSP26,PPARA,PPP5C,CCDC40,RGS3,RNASE1,RXRA,LIMS2,SLC6A11,SLC11A1,IZUMO4,CRTC1,DNAH7,TRPM2,VGF,VIPR2" Drug 2837_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "NDRG2,NME5,SEMA6A,APBB2,APC,APLP1,ATP2A2,CFLAR,LDLRAD4,STX2,DLC1,FAM49B,INPP5B,KCNB1,AFDN,ZNF862,RETREG1,LRP12,PRKAR1B,MAPK10,ZNF821,RASA3,ST6GAL1,ABLIM3,KANSL3,PKNOX2,LIMCH1,KIF13A,ARHGAP26,PLCB1,DMXL2,SLC35G2,AP4E1,TRIO,TRO" Drug 4656_DN Dipyridamole [58-32-2]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ABCG2,NRG2,ENTPD4,ARHGEF10,DZIP3,TM9SF4,TBC1D5,DAPK3,RUSC2,CHRDL1,EDNRA,FEM1B,MBNL2,SCARA3,SRCAP,IFI16,SHISAL1,TJAP1,LSS,NF1,MAPK7,ELOVL2,PID1,RGS4,MCMBP,ZFP30,FRMPD1,FUZ,NLGN1,LIMCH1,TCF4,BHLHB9,CABIN1,UGT8,EVI5" Drug 6130_DN (R)-Propranolol hydrochloride [13071-11-9]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASIC1,CDC42BPA,APC,TPP1,DOCK4,TBC1D5,DBN1,RUSC2,FCF1,TNK2,STX2,ERCC2,FYB1,DISC1,ALDH1L1,TXNL4A,LILRA2,MAP4K5,NCKAP1L,MEF2C,AFF1,NFYA,PDE4B,PRKAB2,TMEM104,PEX26,SS18,SEPT8,TMPO,PARD3,TRPS1,HIRA,ZBTB14,MARCH8,NLRP3" Drug 6780_DN Pimozide [2062-78-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "APC,KIF1A,SLIT2,QKI,BAG4,ARHGEF10,CTH,HDAC4,TM9SF4,GIT2,TOM1,COQ7,ZNF589,FGFR1,CGREF1,SRCAP,MATK,GIT1,LRP12,POLG,PTPN13,GSTCD,CLIP1,SH3BP2,SOX3,TTBK2,NSFL1C,ZKSCAN5,HIRA,UBE3A,VGF,URM1,EPM2A,UBE3B,SMIM8" Drug 6745_DN Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "OGT,KIF1A,ADAM23,MTMR3,B4GALT6,RAB28,CPS1,SLITRK5,ARHGEF4,EPB41L2,MTSS1L,IQCG,TDRKH,HSF2,IL6ST,KHK,MIA2,CNOT4,SLC11A2,PLCD1,ZSCAN32,ZCWPW1,AMBRA1,CCDC88A,ARHGAP26,SPTAN1,SS18,STX1A,PLCB1,TNS1,TRIO,ZNF45,EVI5,MPPE1,PHTF2" Drug 4212_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ASIC1,CDC14B,CDK10,SYNJ1,RAB26,HOMER3,WHRN,NCOR2,ARHGEF10,IPCEF1,PDE4DIP,EDN3,TENM1,COQ7,CORO2B,PDLIM5,DISC1,MSTN,STON1,HLF,ICA1,LAMA2,MEF2C,MMP16,PPARA,PPP2R2B,SUSD4,SCN8A,SLC4A3,PREX2,SNCA,KIF13A,DOCK9,ADAMTS9,EPM2A" Drug 3178_DN Pimozide [2062-78-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,TRMT9B,MARK4,CFLAR,SCAPER,CAMK2G,MAGI1,ARHGEF6,ABCG1,SOCS5,GPRASP1,GIT2,HSD17B14,COQ7,VPS26C,FGFR1,ANKFY1,LMO2,NF1,NFYA,CNOT4,MBOAT7,PRKACB,PTPRG,RGS12,RPS6KA2,SBF1,ZNF821,KIF13A,SATB2,PCDHA6,THRA,REEP1,MPPE1,UBE3B" Drug 1487_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ADCY6,ADORA1,APBB2,PRX,ST3GAL5,SCAPER,HAP1,CNTFR,WHRN,GPRASP1,EDNRA,DLC1,SCARA3,HPCAL4,PCDH17,ADAMTS13,ELOVL5,INPP5B,KCNH2,KIF5A,ADAM22,ZNF862,SETD4,ENPP2,SLC2A5,FAM214B,SNCA,RBM34,DOK5,PLCB1,IQCE,BEX4,TRPM2,SPHK2,PARP11" Drug 3064_UP Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "SPARCL1,ATP2B2,BMP7,ABCG2,INTS1,HEPH,HEYL,FAM13A,EGFR,ERBB2,ABCA8,FGFR3,CHL1,GAD1,SIGLEC8,CSDC2,GUCY1A1,RASSF8,SCIN,KCNJ5,MAPT,ADAM22,NPY,ACSM5,RGS12,ZFHX4,SLC11A1,ARHGAP26,TACR1,TBCEL,RIMBP2,TRO,KCNK12,SLC30A3,SLC17A7" Drug 3095_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "MTUS1,AMPD3,BIN1,APBB2,ADAM23,NRP2,C5,MYRF,CACNA1A,SCARB1,DBT,OPTN,VPS13B,ERCC2,RRAGB,KAT8,ZNF44,ALDH1L1,GPD2,NF1,NINJ2,OGG1,PLTP,PRKAB2,ZSCAN32,BEND5,TCP11L1,KDM4B,DBNDD2,ADGRL3,SYNE1,ZKSCAN5,FLRT2,ZNF74,ST7" Drug 4728_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "ARHGDIG,CA4,ARHGEF1,SCARB1,MAGI1,RCBTB2,B4GALT6,PLAA,WHRN,CSF1R,MFAP3L,EDNRA,FCF1,STX2,PRKAG2,GLYR1,GPD2,MAP4K5,KCNF1,KITLG,STRN3,PRPH,AP1AR,ANKRD6,PEX26,BTBD7,SMARCD3,LIMCH1,PLCB1,PCDHA5,THRA,TMPO,TNS1,MPPE1,TIGD6" Drug 2764_DN Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-03 1.00E+00 2.66E-02 3.00E-01 35 196 "AK2,CFLAR,GYG2,CA4,RAB28,DZIP3,PPP6R2,TM9SF4,TBC1D5,DBT,DTNA,ZNF589,ANKFY1,ERAP1,DISC1,MSL3,GNG4,KPNA5,NF1,SLC25A23,NKAIN1,TCP11L1,SLC6A8,LIMCH1,TSPYL2,SS18,STX1A,SUPT5H,TRIM2,TRIO,VGF,DNALI1,HPS4,RNF170,SENP7" Drug CID000003053 diethylenetriaminepentaacetic acid Stitch 4.53E-03 1.00E+00 2.71E-02 3.05E-01 13 52 "CCK,ARHGAP32,CASP8AP2,EGFR,RASL12,DLL3,MCHR1,NACA,KCNIP1,SST,SSTR1,SSTR2,KAT6B" Drug CID000001136 M-HT Stitch 4.57E-03 1.00E+00 2.73E-02 3.08E-01 16 70 "ACHE,APLP1,APOC1,BCHE,RUNX1T1,CBFA2T2,CHN1,CNR1,CD320,GLUL,HNMT,MAPT,MAPK9,SYP,ZIC1,NETO1" Drug CID000003340 fenoldopam Stitch 4.57E-03 1.00E+00 2.73E-02 3.08E-01 16 70 "ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,ALDH7A1,CACNA2D1,EDNRA,EDNRB,PPP1R1B,CIT,PDE3A,PLCB2,PLCB1" Drug CID000005537 trequinsin Stitch 4.62E-03 1.00E+00 2.76E-02 3.11E-01 14 58 "ADCY5,ADCY6,ADCY8,ALDH7A1,CALM1,ABCC5,FGF1,HP,PDCD2,PDE1C,PDE3A,PDE4B,PDE4D,ABCB1" Drug CID000644241 nilotinib Stitch 4.62E-03 1.00E+00 2.76E-02 3.11E-01 14 58 "ABHD6,BRAP,ABCG2,CSF2RA,EPHB1,FGFR1,JAK2,KIT,KITLG,NTRK2,LAMA1,RET,TEK,FIP1L1" Drug CID000073665 prochloraz Stitch 4.66E-03 1.00E+00 2.78E-02 3.13E-01 29 155 "ADCY5,ADCY6,ADCY8,ADRB2,SEMA7A,APLP1,CACNB4,CCK,CDR1,HDAC9,ERBB4,PCYOX1,FOXO3,PPARGC1A,DCLK2,CIT,ACOT7,IFI16,IGF1,SCIN,MAPT,MYO7A,OPA1,DPF2,SPP1,TBL1X,ICAM5,NELFE,EPM2A" Drug CID000000934 nickel Stitch 4.67E-03 1.00E+00 2.78E-02 3.14E-01 83 552 "ASIC1,ADCY5,ADCY6,ADCY8,PITPNM2,APLP1,NT5C3B,NRP2,CACNA1I,CACNA1G,CA4,CA8,CA12,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,KRIT1,CD86,CDH2,CDO1,CACNA2D2,CLTC,CNR1,COL11A2,PLCXD3,DMPK,EDN1,EDN3,APH1A,TUBD1,EPB41L2,ERBB4,TUBB3,FGF1,SPSB4,POLK,TUBA8,GGT7,GRIA2,PLCD4,CIT,CLASRP,FAM107A,HBA1,FRMD3,TNFAIP8L3,KITLG,MID1,NBL1,SLC11A2,ENPP2,PKD1,PLCB2,PLCD1,POLG,PPP3CA,PPP3CC,PRODH,REV3L,RNASE1,RYR3,COPZ1,NLGN1,SLC8A1,SLC11A1,SLC14A1,PEG10,PLCB1,SMG6,TPCN2,ICAM5,CABIN1,NPL,AMACR,CA14,TUBB2A,TUBB1,SLC30A3,SLC30A4,TUBA1A,SLC17A7" Drug ctd:D012402 Rotenone CTD 4.78E-03 1.00E+00 2.83E-02 3.19E-01 138 983 "ACHE,ADORA2A,MTA3,AGT,TBC1D14,APAF1,GAS7,ARHGDIG,ARNTL,ATP2B2,KIF1A,BARD1,BID,PROM1,WASF1,CALB1,CALB2,CAMK2A,CAMK2B,CAMK2G,CBS,CCNH,CD38,ENTPD2,CPNE6,CNTN1,COX4I1,CRMP1,CRY2,SNCAIP,CSF1,CTH,PPP6R2,FAM131B,CYBB,DAPK1,HEPH,FBXL5,C2CD2L,SV2B,PDCD6IP,DNM1L,FIS1,EDN1,OPTN,PHF20L1,EGFR,CALCRL,TUBD1,RASGRP2,RPS6KC1,TUBA1B,TUBB3,TAOK3,CEP78,FGF1,SUCO,SYNCRIP,FLT1,USP21,CAMKK2,TUBA8,PPARGC1A,TTBK1,GRM8,HBA1,ZHX1,HMGCR,MSL1,IDH3A,IDH3B,IGF1,ITGAM,JAK2,KCNH2,KIF5A,LAMP2,MAPT,MBP,MSR1,NACA,HNRNPM,NFE2L2,ALDH1L2,NNAT,NPY,NTRK2,OPA1,CLDN11,CDK18,PGAM2,ABCB1,PPP2R2B,MAPK3,MAPK9,MAPK10,PTPRD,PTX3,RAD17,RET,SUGCT,GSTCD,FBXW7,MCMBP,LRRK2,AP1AR,TNFRSF19,CASC3,SGK1,AMBRA1,PREX2,SLC6A8,CXXC4,SNCA,CABCOCO1,FNBP1,SPP1,TEK,DNAH7,SIRT1,CHST8,THRA,TIAM1,TK2,CDK20,TRPM2,TUBB2A,RPL7L1,UCHL1,UGT8,PDIA2,VLDLR,WNT7A,NPDC1,TFIP11,TUBA1A,UBE3B,NLRP3" Drug 3464_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.78E-03 1.00E+00 2.83E-02 3.19E-01 31 169 "APAF1,APBB2,KIF1A,LHX2,TBC1D5,RHOBTB1,SACS,EGR3,EIF5,EVL,CAMKK2,B4GALNT1,GRB10,MAPT,MXI1,PIK3R1,ROBO1,FAM102A,TMCC1,CDK19,CAMTA2,PLCB1,ASTN2,TBL1X,ZMAT3,SMUG1,ZNF32,HPS4,UBE3B,PHTF2,NETO2" Drug CID000107831 AC1L32TU Stitch 4.79E-03 1.00E+00 2.83E-02 3.19E-01 9 30 "CALB1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,SST" Drug CID000167551 anacardic acid Stitch 4.79E-03 1.00E+00 2.83E-02 3.19E-01 9 30 "NCOA1,CFLAR,CACNA1I,CACNA1G,HDAC9,KAT7,KAT6B,TUBA1A,KAT6A" Drug CID000126757 GYKI 53655 Stitch 4.79E-03 1.00E+00 2.83E-02 3.19E-01 9 30 "STX2,GAD1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8" Drug CID000000784 H2O2 Stitch 4.81E-03 1.00E+00 2.83E-02 3.19E-01 163 1183 "ACHE,ADCY5,ADCY6,ADCY8,AMPH,APC,APLP1,MAGEE2,DDO,CDK10,PRX,ARHGDIA,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ALDH7A1,BARD1,BCS1L,CFLAR,BTK,CACNA1A,CALM1,CBS,CCK,CCNT1,SCARB1,LRBA,CDH2,CDO1,CACNA2D2,CLCN3,COL9A1,COL9A3,CREM,HAPLN1,GDA,CS,PLCXD3,CYBB,CHRDL1,DOCK2,ACOT8,RCAN1,DTNB,TOM1,DNM1L,AASDH,EDN1,EGFR,COQ7,ERBB2,ERBB4,PIPOX,TUBA1B,PTK2B,FCGR3A,FDFT1,FECH,FGFR1,POLK,SCARA3,PCYOX1,FOXO3,SMC2,ATP6V1H,SESN1,GFER,AIFM3,KCNMB4,LOXL3,GPD2,PLCD4,GRIN2C,HBA1,TNFAIP8L3,HMGCR,HP,IGF1,IL12A,ITGA7,ITGAM,KCNB1,KCND2,STMN1,LIG4,ASPRV1,MBP,MIA2,PPM1L,MSR1,NCF2,NDP,NFE2L2,NFIX,SLC11A2,NTRK2,OGG1,PAX6,ABCB1,PIK3C2A,PIK3R1,PLCB2,PLCD1,SMOX,FA2H,POLG,PPP2R2B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PRODH,NDUFS7,PTK2,PPP2R3C,RBBP8,REV3L,GSTCD,RPE,RYR3,S100B,MAPK12,SMPD3,HSPA4L,FNDC3A,SIRT2,SLC11A1,SLC12A4,ZNF667,SNCA,SST,ADHFE1,PLCB1,SYP,SYT1,MMS19,FBXW11,SMG6,CYB561A3,SIRT1,ACTR6,TMPO,CABIN1,PIK3R5,SMUG1,NEIL2,TRPM2,TSC2,TST,UBC,WRN,TUBA1A,PLD4,MSRB3,NETO1" Drug CID000388647 AC1L8WBM Stitch 4.81E-03 1.00E+00 2.83E-02 3.19E-01 26 135 "SYN3,ACTN1,ADRA1B,DYNLL1,CBFA2T2,CLTB,CNR1,SLC25A18,ERBB2,TLR7,GRIA2,MAP4K5,SYNPO,IL12A,KITLG,PIK3R1,SLC6A11,SLC14A1,ERC1,SSTR1,SYN1,SYN2,PJA1,THRA,TK2,FXR1" Drug 3902_UP Withaferin A [5119-48-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.82E-03 1.00E+00 2.83E-02 3.19E-01 32 176 "BEGAIN,AMPD3,BIN1,APAF1,PPFIA3,RGS20,NRP2,CAMK2B,CLCN3,CREM,BAIAP2,GATM,GRB10,IL6R,MBP,SERPINI1,PLTP,LRP12,NECAB2,MINDY2,CEP41,MAPK7,PTPRH,MORC4,RPS6KA2,CLIP1,JMJD6,TBCEL,OBSL1,VLDLR,SLC30A3,KCNAB1" Drug CID000000528 C05700 Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "CBS,CTH,GPD1,MAT2A,SHMT2" Drug CID000486048 Sm28 Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "SUMF2,NELFCD,MAP4,PPP2R2C,GSTCD" Drug CID003037006 4-iodotamoxifen Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "ALDH7A1,CALM1,FHL1,ABCB1,PDLIM2" Drug CID000031297 mesyl chloride Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "BOC,FGFR1,FLT1,PPARA,SYNE1" Drug CID000030814 DCDM Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "ADRA1B,ADRB2,STX2,FOLH1,STX1A" Drug CID005311185 iodoclonidine Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "ADRA1B,ADRB2,AGT,SST,TK2" Drug CID006603857 GW2974 Stitch 4.82E-03 1.00E+00 2.83E-02 3.19E-01 5 11 "EGFR,ERBB2,PTK2B,ASPRV1,RET" Drug 2053_UP Disulfiram [97-77-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-03 1.00E+00 2.83E-02 3.19E-01 33 183 "CDC42BPA,BACH1,HAP1,CARS,NRXN3,CLCN3,PICK1,CREM,CRY2,AATK,PDE4DIP,FCF1,MBNL2,MRNIP,ZNF589,IQCG,SRCAP,INPP5B,PCDH9,PTPRE,HSPA4L,SGK1,PEX26,PDZD2,KDM4C,TSPYL2,THSD1,ARC,CHST8,TK2,UBE2H,LAT2,ZFAND5" Drug 7389_DN 0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.84E-03 1.00E+00 2.83E-02 3.19E-01 33 183 "ACTN1,ADRB2,MTUS1,MYRF,PRC1,CDC25B,B4GALT6,HOMER3,ENTPD4,VCAN,SLITRK5,EGFR,ERBB2,SCML2,ZNF589,SCARA3,PDLIM5,FYN,DBF4,MBD1,NFYA,PDE1C,GPSM2,NLE1,FAM214B,LIMCH1,PBLD,SS18,VPS13A,PLPPR2,ZBTB14,VPS35L,PHTF2" Drug 2576_UP Alexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.84E-03 1.00E+00 2.83E-02 3.19E-01 33 183 "CDC42BPA,SLC16A4,CLGN,AKAP7,CREM,CRY2,ARHGEF10,CSNK1E,PDE4DIP,DZIP3,CTH,HDAC9,EGR3,EIF1,ST3GAL6,FYN,ZNF276,GRB10,MT1M,P2RX7,ENPP2,CNTLN,RPS6KA2,TRAPPC13,ATXN7,ERBIN,ARHGEF9,KIAA1107,SZT2,SIRT1,TRPS1,FLRT2,LAT2" Drug 5964_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,SEMA6A,TRMT9B,SEMA7A,APC,CFAP410,CAPN3,LHX2,RAB33A,CSF1,SPOCK2,JAKMIP2,OPTN,ELN,HSD17B14,EPHB1,FGFR3,ALDH1L1,STON1,GPER1,PCLO,NXPH3,CNOT4,NPY,LRP12,SEMA6D,ASAP3,SLC11A1,ARHGAP26,THSD1,TAL1,TNS2,TLR4,RPRM,PLSCR4" Drug 6229_DN Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BMP7,SYNJ2,RAB28,DCAF8,KIAA0753,USPL1,FKTN,CGREF1,SYT17,MALT1,DIDO1,AGBL5,MAP4,PMP22,STRN3,PPP3CC,RIPOR1,TMEM231,MSANTD2,PBRM1,CCDC25,TRAPPC13,SAFB,SGK1,KIF16B,ZNF430,ELMO2,INTS9,SP2,UHRF1BP1L,SS18,NSFL1C,DNMBP,VAV1,LMF1" Drug 2788_DN Xylazine [7361-61-7]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APC,APOC1,CFLAR,C5,CBR1,ENTPD4,LYPD1,DTNA,FEM1B,ANKMY1,KAT8,FER,BAIAP2,GLYR1,BTN2A1,SLC2A6,ATXN2L,IL6ST,KCNH2,LIG4,ADAM22,MYO9A,NLE1,MBOAT7,RAD51D,ZCWPW1,AMBRA1,ZKSCAN3,COA1,ZBTB43,MCF2L,PCDHA6,TRIO,HPS4,EPM2A" Drug 282_UP fludrocortisone acetate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "RALGAPA1,ABR,ATP2B2,CAMK2B,TAOK2,COL4A5,AATK,C2CD2L,RCAN1,MBNL2,FGFR1,SEC23B,RUNDC3A,GLYR1,NCKAP1L,NF1,NPR2,OPRL1,PLCD1,PLEC,C1orf54,SEMA6D,SH3BP2,ST6GAL1,SLC9A5,LMO3,NXT2,PHLDB1,PRRC2C,COBL,SZT2,CHST8,UBE3A,GDPD5,MPPE1" Drug 2541_UP Propidium iodide [25535-16-4]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APAF1,NCOA1,SYNJ1,PTBP2,CHN1,EPS15L1,HAPLN1,SLITRK5,GSDME,FAM13A,MBNL2,ING4,COQ7,REEP2,OLFM1,FHL1,FYB1,GFER,CRCP,GUCY1A1,ATXN2L,KCNN1,PCDH9,PFKFB2,PFKFB4,CCSER2,PPP5C,RIPOR1,FBXW7,ZNF821,PEX26,TMCC1,DOK5,ZBTB38,EMSY" Drug 2513_DN Delsoline [509-18-2]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,DNAH17,ADAM15,C5,LDLRAD4,CAMK2G,BAG4,DAPK3,RCAN1,DTNA,TOM1,MRNIP,RASGRP2,VPS26C,KAT8,EFCAB2,SEPT9,COPS8,LILRA2,CACFD1,SLC2A6,MAP4,CNOT4,PLTP,TMEM231,ZCWPW1,MRAS,SNCA,STX1A,ARHGEF9,EXOC7,HIRA,NT5M,UBE3B,ACTR3B" Drug 5771_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "RALGAPA1,TRMT9B,RASL11B,ADAM23,CACNA1I,CBFA2T2,ARHGAP22,HOMER3,CABP1,ENTPD4,SH2B1,CRMP1,NCOR2,ABCG1,DMPK,MBNL2,FYB1,DENND2A,GFER,HPGDS,POLL,GRIK5,CACFD1,ATXN2L,MMP16,NOVA2,SLC11A2,POLG,DCHS2,C1orf54,ASAP3,ZHX3,DICER1,TK2,SLC17A7" Drug 1441_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BRAP,APAF1,EIF4G3,MTMR2,WASF1,KRIT1,RCBTB2,SRSF11,OSBPL3,FBXL5,RCAN1,SUGP2,EGR3,KCTD3,ANKMY1,ACSL4,FECH,ATP2C1,ERAP1,MUM1,MBNL1,LRP12,C1orf109,ATXN7,CCDC88A,KBTBD4,ELMO2,MAPKBP1,CDK19,SAMSN1,SS18,PUM2,TSN,HIRA,FLRT2" Drug 1149_DN "estradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "C1QTNF3,ARRB2,NCOA1,CAST,CD86,PLAA,QKI,CSF1R,ARHGAP32,ZNF337,ERCC2,SEMA4D,PDLIM5,GALC,ARFIP1,DIDO1,MAP4K5,HNMT,INPP5B,AFF1,SLC11A2,RETREG1,PLTP,RNASEL,SEC14L1,FNDC3A,ZHX3,CLASP2,EXOC7,TBL1X,THRA,HIRA,UBTF,ZNF142,EVI5" Drug 1721_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,ADD2,AMT,APOC1,BACH1,BMP7,TAOK2,CLCN3,CRY2,CRYM,INTS1,STX2,POMT1,TDRKH,MYT1,NEFH,NTRK3,OCRL,OPRL1,CCSER2,GPSM2,PLEC,MBOAT7,MAPK10,DEF8,CCDC40,RNASEL,ATF7IP,DBNDD2,NXT2,PDLIM2,TK2,PARD3,ZNF32,MARCH8" Drug 5004_UP Luteolin [491-70-3]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SYN3,TRMT9B,APOC1,RGS20,ALDH7A1,ADAM23,BAIAP3,CACNA2D2,NRG2,TMCC2,DTNA,EGR3,CDKL3,DLC1,ZNF589,FGFR3,GSN,FICD,KCNH2,MGAT3,ZNF862,NF1,NNAT,SERPINI1,LRRN3,PPP5C,TTC13,KANSL3,COA1,ATP10B,SYN2,WSCD1,SLC35G2,SEMA3B,TIGD6" Drug 3445_UP Vidarabine [5536-17-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BIN1,RGS20,SLC2A11,CFLAR,RCBTB2,ENTPD4,CSF1R,GREB1,CDON,ANKMY1,REEP2,FGFR1,FHL1,PDLIM5,SEPT9,TXNL4A,ITPKB,KHK,MITF,ZNF862,C19orf57,PRKAR1B,GTDC1,EMID1,RXRA,ASAP3,FAM214B,KANSL3,SNCA,TMCC1,SPTAN1,TMEM121,SLC44A1,NDRG4,AP3B2" Drug 1536_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,PLA2G4C,NUMB,SLC2A11,SYNJ2,ARHGAP33,CACNA2D2,SRSF11,HOMER3,CNTN1,SLC4A8,HDAC4,SPOCK2,DTNA,MBNL2,RCAN2,BAIAP2,TRMO,PDLIM5,ATP2C1,GNAL,KCNJ5,MMP16,PDE4A,CEP41,ELOVL2,ROBO1,EMID1,SEMA6D,STUM,BTBD7,SPART,TTBK2,ZBTB14,RNF170" Drug 7512_DN CP-863187 [668981-07-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,ARNTL,ZBTB10,ADAM15,CFLAR,SYNJ1,CHN1,QKI,CNN3,ARHGAP32,E2F5,SEC24B,STAU2,TRAF3IP2,ATXN2L,KIF2A,IPO5,MBNL1,NCF2,NF1,OCRL,LRP12,RDX,HSPA4L,SH3GL3,FNDC3A,TTC17,LIMCH1,PDZD2,PEG10,FBXW11,FRYL,TRIO,TRPS1,CLDND1" Drug 508_UP staurosporine; Up 200; 0.01uM; SKMEL5; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMT,ATP2B2,CALB2,CAMK2G,CDH2,DLGAP1,CRHBP,TNK2,FGF1,BAIAP2,FAM107A,GUCY1A1,ICA1,KCNH2,LIG4,MBP,MIA2,NPY,NTRK2,PALM,PLCD1,CEP41,PRKAR1B,KLK6,RIPOR1,TMEM231,CCDC40,RBBP6,SH3GL3,KBTBD4,PLCB1,TACR1,PHF24,SLC17A7,KCNAB1" Drug 4766_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "FGD2,APBA2,ARSE,CDK13,RASL11B,ATP1A3,NRXN3,AKAP7,COL9A3,CRMP1,CSF1,ARHGAP24,HIPK3,HEYL,FGFR1,ADAM28,RUNDC3A,RAB30,GSN,GSTM5,IFI16,TJAP1,KCNJ5,ADAM22,MX1,MAPK10,C1orf54,SH3GL3,MAPKBP1,SNCA,ATP10B,PCDHGA10,SLC17A7,PLSCR4,JPH3" Drug 2334_UP Riluzole hydrochloride; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMH,ARRB1,MARK4,NCOA1,N4BP2L1,RIPK1,SYNJ2,CAMK2B,HIP1R,CD38,CREM,PPP1R16B,GSDME,EDN3,COQ7,ERBB2,FHL1,INPP5K,LILRA2,GRB10,ADAM22,NOVA2,GDPD2,KHDRBS2,RET,GSTCD,TRAPPC13,MRAS,FAM102A,KDM4C,WSCD1,TCF4,CDK20,FLRT2,SLC17A7" Drug 6934_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BRAP,MTUS1,RIPK1,CA12,CAMK2G,HOMER3,CREM,DCAF8,DAPK3,FBXL5,DNM1,DPH1,CELSR3,POLR1B,TRMO,ZNF276,GRM8,MAP4K5,HNMT,HSF2,NF1,ZCWPW1,GTDC1,SAFB,AMBRA1,BTBD7,TROVE2,PDLIM2,TIAM1,KAT6B,LMF1,XRCC4,FTSJ1,MPPE1,EPM2A" Drug 3350_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "C1QTNF3,AMPD3,APC,PPFIA3,CLGN,FOXN3,DCAF4,DOCK4,DCAF8,DAPK3,FBXL5,HSD17B14,STX2,RRAGB,PDLIM5,PRELID3A,ERAP1,SRCAP,ELOVL5,KCNJ5,MPP2,PDPK1,PLCD1,PPP5C,PRPH,ZCWPW1,RGS12,RPS6KA2,SEC14L1,PEX26,GLT8D1,EXOC7,KIAA1107,TK2,KLC2" Drug 5589_DN clozapine; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "LTBP4,APOC1,PDE8B,MARK4,SLC2A11,RIPK1,SYNJ2,GYG2,SGCE,CAMK2G,SLIT2,AKAP7,COQ7,EZH1,DISC1,SRCAP,MALT1,MSL3,GPER1,CNTRL,ADAMTS13,GRIK5,ELOVL5,NF1,LRRN3,TCP11L1,ABLIM3,SMARCD3,ZHX3,PHLDB1,SMG6,WSCD1,TNS1,PLSCR4,ADAMTSL3" Drug 2796_DN Bicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,AP2A2,CDC42BPA,PPFIA3,ARHGDIG,BMP7,CCNT1,USP2,HOMER3,ENTPD4,CTH,DBN1,EGFR,ERBB2,ZNF589,FGFR1,BAIAP2,SEMA4D,B4GALNT1,TXNL4A,CACFD1,GSN,DHX35,KPNA5,MATK,OGG1,POLG,FBXW7,TROVE2,KANK1,EXOC7,RPGRIP1L,PARD3,REEP1,SENP7" Drug 2804_DN Boldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,APOC1,ZBTB10,PLEKHB1,LHX2,PLAA,SLC4A8,BAG4,SIPA1L1,DCAF8,B3GAT3,SGSM2,DTNA,EDNRA,EZH1,FECH,BAIAP2,GHR,TXNL4A,KCNH2,SETD4,SLC25A23,FSD1,PTK2,RIPOR1,ZCWPW1,ABLIM3,EPN2,MAPKBP1,THSD1,ANKRD12,MCF2L,BEX4,MPPE1,SENP7" Drug 6664_UP Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "KCNAB2,APBB2,PPP4R4,N4BP2L1,BMPR1B,CFAP410,CBS,CSF1,BRINP1,MFAP3L,SV2B,DMPK,DUSP9,ERGIC3,IQGAP2,ALDH1L1,POLL,CACFD1,AFDN,MMP16,ADAM22,PDE4B,PTN,PTPRN2,KHDRBS2,ZNF334,SNCA,ZFPM2,AP4E1,TIMP4,R3HDM1,TPM1,ZNF74,ZNF225,KCNAB1" Drug 6050_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,APBB2,ST3GAL5,MTMR2,CACNA1I,LDLRAD4,CFAP410,CAMK2G,USP2,CBFA2T2,CACNA2D2,RAB28,CNTFR,VCAN,DZIP3,PHF20L1,FGF12,COPS8,GLYR1,MSL3,TDRKH,HLF,HNMT,INPP5B,KCNN2,ADAM22,ZNF862,PPP5C,ZFHX4,TCP11L1,SEMA6D,SPTAN1,RPGRIP1L,ZKSCAN5,ZNF45" Drug 5326_DN Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "EP400,APAF1,PPFIA3,NUMB,MPDZ,BMP7,SYNJ2,C5,KRIT1,ARHGEF2,HOMER3,PCOLCE2,EPB41L2,FGFR3,BAIAP2,PRKAG2,GAA,INPP5K,KHK,MBP,MEIS2,PTK2,AP1AR,FERMT1,FBXO11,RCOR3,SPATA7,ZSWIM8,TSPYL2,NXT2,KANK1,TRIM2,FRYL,KAT6B,TRIO" Drug 4127_DN Sulmazole [73384-60-8]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA2A,LTBP4,SEMA7A,PDE8B,MARK4,CAMK2B,CBFA2T2,SCARB1,CRMP1,ARHGEF10,CYBB,RASSF2,EDN1,ING4,ERCC2,VPS26C,ZNF589,FHL1,DISC1,GRIK5,GRM8,HLF,AFF1,NNAT,NLE1,CARF,TCP11L1,SH3GL3,BTBD7,SNAP25,SNCA,CLSTN2,TBCEL,ZEB1,PCDHGB6" Drug 2967_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "KCNAB2,SLC4A4,FUBP1,CA8,ARHGEF1,ENTPD6,CREM,CRMP1,GPRASP1,DBT,HIPK3,FCF1,TNK2,RASGRP2,ERCC2,TPK1,LAMA2,AFDN,N6AMT1,SETD4,PDE4B,CCSER2,POLG,CEP41,GALNT10,SNCA,RBM34,IQSEC2,SS18,EXOC7,PDLIM2,TBL1X,THRA,TK2,UBTF" Drug 5480_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA2A,AGT,NME5,GAS7,ATP2A2,GYG2,LDLRAD4,CHN2,CNTNAP2,SPOCK2,DOCK2,OLFM1,ANKFY1,GNAO1,CNTRL,GRIK5,HSF2,MMP16,ADAM22,PGAM2,RETREG1,PLEC,RGS12,RPS6KA2,ZNF821,ABLIM3,ELMO2,HECW1,ZC3H13,RPGRIP1L,AMACR,VIPR2,ZNF45,PARP11,FAM13C" Drug 3029_DN Dimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "MTUS1,BIN1,AZGP1,KSR1,SYNJ1,RUBCN,EXOG,CELSR3,PLXNC1,FCGRT,FHL1,SEPT9,INPP5K,LILRA2,TJAP1,JAK2,SMAD1,NEK1,NFYA,NINJ2,CNOT4,LRP12,POLG,TRAPPC13,MAPKBP1,DOP1A,NSFL1C,PLCB1,KIAA1107,DMXL2,TNS2,TRPS1,ZKSCAN5,ZNF225,KCNAB1" Drug 6957_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADCY6,APC,CDC14B,CDK10,CA12,SYNGR3,CRY2,ABCG1,GIT2,LYPD1,DPH1,IRAK4,MTSS1L,VPS26C,EZH1,FHL1,SPACA9,GRM8,HNMT,LYRM9,NF1,NFYA,RAD51D,RPS6KA2,EPN2,ZKSCAN3,VGF,VIPR2,LMF1,NDRG4,MAP3K12,HPS4,FIP1L1,RNF170,AAAS" Drug 1208_DN "estradiol, USP; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "C1QTNF1,BIN1,APAF1,KCNAB2,PPFIA3,BCHE,SCAPER,ABI3BP,APPL1,OPTN,MBNL2,C3orf18,FGFR1,IL6R,MATN3,SLC11A2,PIK3R1,STRN3,RETREG2,FSD1,PRPH,RIPOR1,NUDT11,MCMBP,SNCA,SPTAN1,SEPT8,STX1A,WSCD1,ZNF34,METTL3,SMUG1,HIRA,ZNF189,UBE3B" Drug 2868_DN Phenindione [83-12-5]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APOC1,CDK10,MPDZ,CFLAR,SCAPER,ASIC3,ENTPD4,ABCG1,DBN1,B3GAT3,CELSR3,VPS13B,FER,FGFR1,PDLIM5,SRCAP,TXNL4A,BTN2A1,INPP1,TM6SF1,MITF,GIT1,SLC11A2,PDPK1,PLCD1,SLC25A23,MINDY2,RGS3,SLC25A36,GSTCD,CCDC25,SLC22A4,SPTAN1,KAT6B,CIAPIN1" Drug 5905_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SEMA6A,LTBP4,APLP1,N4BP2L1,CRLF1,SULT4A1,RCHY1,RASSF2,HSD17B14,RASGRP2,FCGRT,CPLX2,RAB30,STON1,SHISAL1,KCNQ3,LSS,NTRK3,PALM,PCDHGC3,PLTP,MAPK10,GRAMD1C,RFX2,RFX3,KCTD17,ZFHX4,PNMA8A,SEMA6D,RASA3,NMNAT2,ZNF423,HEY1,KCNK12,SLC17A7" Drug 7553_DN CP-863187 [668981-07-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "FAM131A,BAIAP3,CAMK2B,MAGI1,CRLF1,RAB33A,QKI,HOMER3,NCOR2,DAPK3,EIF5,COQ7,KCNMB4,GNG4,NXPH3,ATXN2L,ELOVL5,KCNN1,MATK,MIA2,AFDN,MSI1,RETREG1,LRP12,PPP3CC,TCP11L1,SIRT2,ZKSCAN3,SMARCD3,SNCA,SP4,PBLD,ITPRID2,ZKSCAN5,REEP1" Drug 3242_UP Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,NDRG2,ADORA1,SEMA6A,SPOP,TRMT9B,AMH,BIN1,ARHGDIG,ATP6V0A1,TAOK2,QKI,ENTPD4,DTNA,MBNL2,EPB41L2,GLYR1,ICA1,LMO2,MAN2A2,MMP16,ZNF862,PALM,PLCD1,NECAB2,MAPK7,RPS6KA2,FAM214B,DOP1A,ZNF423,WSCD1,UPF3A,EVI5,KAT6A,PHTF2" Drug 203_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AK2,CDC42BPA,ARNTL,EIF4G3,CFAP410,TBRG4,CNTN1,AKAP7,DBT,C2CD2L,DRP2,ANKRD46,MBNL2,EPB41L2,ANKMY1,F5,PDLIM5,MALT1,RUNDC3A,GRIK5,AGBL5,IRF8,MMP17,OGG1,ZSCAN32,PTPRG,SUSD4,GAL3ST4,ZNF331,CHD9,POGZ,TRIM2,TSN,ZNF142,ZFAND5" Drug 4979_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SYN3,ASIC1,NME5,SPARCL1,APOC1,SYNJ2,GYG2,SGCE,ARHGAP33,DGKG,MFAP3L,EXOG,KHDRBS3,GAD1,SRCAP,LYVE1,GPER1,HLF,KCNH2,LAMA2,MX1,NF1,P2RY1,RETREG1,PRKCB,SAMD9,SEMA6D,LIMS2,SNCA,KIF13A,PLCB1,ASTN2,WSCD1,SIN3B,HIF3A" Drug 3171_DN Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "C1QTNF3,APBB2,APC,PPFIA3,SCAPER,CFAP410,GPRASP1,FCF1,CNNM1,OPTN,EIF5,ING4,COQ7,FECH,FGFR1,ANKFY1,PRELID3A,CGREF1,TDRKH,GRB10,IL6ST,NFYA,PRKAB2,PRKAR1B,ZNF821,FUZ,KIF13A,THSD1,TACC1,NSD1,ZNF34,TPM1,PLPPR2,VIPR2,EVI5" Drug 1401_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "EIF4G3,N4BP2L1,CA12,CNOT8,AKAP7,CRYM,EPB41L2,VPS26C,SEC23B,MAP4K5,KCNN2,LAMP2,MAP4,PLCD1,RETREG2,PPM1B,PRKACB,CLIP1,ATXN7,CHD9,KBTBD4,MAPKBP1,FNBP1,SPART,TROVE2,ITPRID2,ST5,STAU1,SEPT8,KLHL7,VPS13A,SIRT1,WIPF1,XRCC4,EVI5" Drug 3796_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SYN3,ADD2,AZGP1,ADGRB3,RGS9,MTMR3,RUNX1T1,SULT4A1,MBNL2,ABCA8,GATM,NEU3,GNAO1,GRM8,GUCY1B1,IGF1,MGAT3,MMP17,NOVA2,NPTX2,GPR85,DUSP26,C19orf57,PRKAR1B,WDR25,CNTLN,MARCH1,ZMAT4,RGS12,PNMA8A,CNKSR2,KANSL3,PKNOX2,DOP1A,PRDM10" Drug 7510_DN 0393-0188; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG3,ADAM15,CNOT8,QKI,ENTPD4,MATR3,SPOCK3,YAF2,EPB41L2,FHL1,OGA,COPS8,JAK2,NF1,NFYA,ZFYVE21,LRRN3,BCAS3,ZSCAN32,GTDC1,RGS4,SH3BP2,SH3GL3,WDR37,SLC4A3,KIF13A,LMBRD1,ZBTB43,FBXW11,TRIM2,NR2C2,HIRA,UBE2H,TRIM9,FZD3" Drug 3425_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AP2A2,EPB41L5,BMP7,GYG2,SCARB1,TAOK2,CREM,USP6NL,DTNA,PHF20L1,CDKL3,SCML2,ANKFY1,FAM49B,GRB10,MAN1B1,DHX35,POLG,PRPH,CNNM2,TMEM104,ZCWPW1,TRAPPC13,KIF16B,SPATA7,ERC1,TSPYL2,SS18,VPS13A,TNS2,TPM1,TSC1,HIRA,UBTF,WRN" Drug 1042_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "CDC42BPA,CDC14B,ARRB1,ARHGEF7,KYAT1,RAB28,QKI,ABCG1,DCAF8,GIT2,DBT,C2CD2L,LYPD1,SGSM2,CGREF1,GLYR1,GRB10,MAP4K5,HSF2,KHK,SETD4,CCSER2,STRN3,SLC25A36,TCP11L1,BTBD7,ZSWIM8,KDM4C,CDK19,ZBTB43,ELOVL4,TACC1,DNMBP,TRIM2,ZNF24" Drug 663_DN U0125; Down 200; 1uM; PC3; HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BIN1,PPFIA3,NRP2,CFLAR,SYNJ1,ST3GAL5,CRMP1,SGSM2,DTNA,MBNL2,EPB41L2,OLFM1,FGFR1,BAIAP2,CAMKK2,CELF1,SESN1,GLYR1,GNG4,PRRC2B,FAM107A,KCNH2,KIF5A,PAXBP1,MPP2,PIK3R1,MBOAT7,NUDT11,SEMA6D,SBF1,TCF4,SZT2,TRPM2,TRPS1,SSBP2" Drug 6830_UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SEMA7A,APBA2,GAS7,ALDH7A1,ARHGEF2,VCAN,PDE4DIP,SLITRK5,RUSC2,SPOCK3,CDON,TNK2,NCALD,PTK2B,ADAM28,RUNDC3A,STON1,KCNB1,ADAM22,PGAM2,SLC25A23,PTCH1,PTPRO,FAT4,RFX2,SEMA6D,ASAP3,SNCA,DMXL2,TNS2,FAM155A,VLDLR,XRCC4,SLC17A7,KAT6A" Drug 2985_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "PPFIA4,APBB2,BCL7A,SCAPER,CACNB4,SOCS6,TAOK2,HOMER3,IQCK,ARHGEF10,PDE4DIP,SLITRK5,RUBCN,RASGRP2,DLC1,ZNF589,INPP5K,AHDC1,ADAM28,RETREG1,PPARA,ZCWPW1,KHDRBS2,ZDHHC14,TCP11L1,FAM214B,SNCA,IZUMO4,SPTAN1,SLC44A1,TPM1,TRO,EVI5,PCBP4,PARP11" Drug 4618_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SLC4A4,NRP2,CA8,SEPT7,RAB28,FAM149A,NRG2,HAPLN1,CSF1,VCAN,SPOCK2,MFAP3L,EDNRA,APC2,HPGDS,GRM2,GRM8,KCNJ5,MAN2A2,MATN3,LYRM9,NEFM,NF1,OGG1,PDE4D,RETREG1,PPARA,SLC2A5,ZNF423,PHLDB1,SYN2,TBCEL,VIPR2,REEP1,SLC30A4" Drug 3_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABR,ALCAM,ANK2,DNAH17,SYNJ2,SCARB1,MAGI1,LHX2,ARHGEF6,GAPVD1,INTS1,DMPK,MBNL2,PLEKHA1,RCAN2,L1CAM,MBNL1,ADAM22,NF1,SMOX,C19orf57,CEP41,VPS13C,TTC13,RBBP6,STUM,ELMO2,SSTR2,LARP4,DIP2A,OBSL1,UCHL1,LMF1,CLDND1,GDPD5" Drug 4478_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ANK2,APC,CDK13,NRP2,KSR1,CACNA1G,LDLRAD4,TAOK2,NCOR2,ARHGEF10,VCAN,MFAP3L,CDON,EDNRA,NCALD,FYB1,FYN,SPACA9,GRM8,ITGA7,KCNF1,NOVA2,DCHS2,ZSCAN32,KHDRBS2,RGS12,SLC11A1,SNAP25,TSNAXIP1,KLHL4,TK2,LAT2,ZNF711,KCNAB1,TIGD6" Drug 1843_DN Benzonatate [104-31-4]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,ACTN1,BRAP,NCOA1,BCL7A,SCAPER,CAMK2G,CAST,CD86,SPATA2,PHF20L1,ENO2,PRRC2B,MUM1,DHX35,ZNF862,CNOT4,PPP5C,REV3L,MCMBP,CLIP1,MAPK12,ATXN7,FBXO11,SLC2A5,SLC6A8,KDM4B,ZNF302,PLCB1,DMXL2,KAT6B,TNS1,HIRA,UBTF,MAP3K12" Drug 4135_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ALDH7A1,N4BP2L1,CBFA2T2,WHRN,AATK,PDE4DIP,DTNB,SNX29,NRN1,PTK2B,SIGLEC8,NEU3,ATXN2L,ICA1,KCNH2,KCNJ5,KCNN1,MID1,ADAM22,CLDN11,GPR85,RASGRF1,RGS12,RPS6KA2,SALL1,ZFP2,SH3BP2,CNKSR2,DZIP1,SLC2A5,SMARCD3,NMNAT2,WSCD1,FAM155A,WIPF1" Drug 3985_DN Troleandomycin [2751-09-9]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "TRMT9B,BIN1,ATP2A2,CHN2,B4GALT6,RAB26,CREM,SH2B1,PARD6A,MBNL2,IRAK4,MRNIP,FAM49B,MSL3,MUM1,LMO2,MN1,NFYA,PPARA,SNRK,RIPOR1,RXRA,ASAP3,NLGN1,ELMO2,RBM34,DDN,THSD1,SS18,ASTN2,ZKSCAN5,LMF1,REEP1,SH3GLB2,MPPE1" Drug 3411_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AP2A2,ALCAM,NCOA1,NUMB,ATP2A2,BCL7A,CCNT1,FOXN3,TAOK2,CLCN3,QKI,LRIG1,SOCS5,PDE4DIP,GPRASP1,LYPD1,ZNF44,SYT17,INPP5K,PRRC2B,IL6ST,MAPT,PIK3R1,MBOAT7,PRKAR1B,PRPH,ZCWPW1,SLC25A36,FAM192A,SH3BP2,EPN2,PBLD,ELOVL4,UBE3A,UPF3A" Drug 2779_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "GAS7,MARK4,KSR1,CACNA1I,KALRN,CAMK2B,ARHGAP33,AKAP6,NCOR2,CSNK1E,DYNC1I1,SHANK1,DUSP9,IGSF6,FGFR3,HPGDS,TJAP1,MAP4,MEF2C,MID1,AFF1,CDK18,PLTP,PPP2R2B,PPP5C,KLHL11,SH3BP2,FRMPD1,CXXC4,SNCA,HECW1,SPP1,EXOC7,TBCEL,TNS1" Drug 4777_DN Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AK2,PPFIA3,STX16,KIF1A,GYG2,SLC25A14,KRIT1,HOMER3,AKAP7,CREM,ABCG1,CSNK1E,PDE4DIP,MFAP3L,FBXL5,SUGP2,FKTN,FGFR1,PDLIM5,MPP6,MAP4,ZNF862,PRKAB2,MSANTD2,SBF1,SGK1,SH3BP2,TMCC1,SPTAN1,TTBK2,EXOC7,TBL1X,DOCK9,VPS35L,KAT6A" Drug 2072_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,SEMA4G,SLC4A4,ADAM23,SCAPER,PLEKHB1,NRXN3,CLCN3,ABCG2,ABCG1,DCAF4,FCF1,COQ7,CDKL3,CINP,SIGLEC8,GCNT2,GRIK5,LMO2,MEIS1,MMP16,MX1,NEK1,PALM,APTX,GAL3ST4,EMID1,TRAPPC13,SH3BGR,CEP68,RGL1,KIAA0930,ZNF711,MAP3K12,EMSY" Drug 7149_DN Aconitine [302-27-2]; Down 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NME5,EP400,SLC4A4,CFLAR,QKI,HOMER3,HAPLN1,DCAF8,SGSM2,MFSD10,STX2,FGFR1,EFCAB2,B4GALNT1,POLL,RNFT2,GUCY1B1,HNMT,LIG4,MAP4,NLE1,KLK6,RGS3,RGS4,TRA2B,FNBP1,ERC1,PBLD,SIN3B,TMEM121,ZNF34,LMF1,NDRG4,SMIM8,ADAMTSL3" Drug 5387_DN Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SEMA6A,CDC42BPA,FAM131A,PPFIA3,PPP4R4,ADAM15,SIPA1L1,CNTNAP2,DBT,MFAP3L,ING4,MRNIP,HSD17B14,ACSL4,KAT8,SPACA9,HNMT,ITPKB,IPO5,KITLG,ADAM22,PLXNB1,STRN3,PRPH,SH3BP2,ASAP3,ANKRD6,ZHX3,LHPP,ST5,PLCB1,ASTN2,TNS2,PCDHA6,GDPD5" Drug 3026_UP Ioversol [87771-40-2]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,SEMA6A,ALK,DDO,APOC1,CDC14B,ATP1A3,RGS9,SOCS6,ZNF337,DGKB,TMCC2,HEYL,SRPK3,ELN,EPB41,KAT8,PRELID3A,ALDH1L1,GFER,ZNF276,GLI2,IL6ST,LAMA2,MMP16,NFIX,POU6F1,PTH1R,SEMA6D,UNC5B,ARHGAP26,PHF24,TIAM1,LMF1,KCNAB1" Drug 2275_DN Nimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMPD3,APBA2,APBB2,PPP4R4,DNAH17,GYG2,CAMK2B,PLEKHB1,SLIT2,HOMER3,CNTN1,DTNA,TRMO,SRCAP,POLL,CACFD1,ITPKB,KCNN2,ZNF862,SLC11A2,CDK18,PLCD1,ZDHHC14,RGS3,KLHDC8A,ZNF821,ABLIM3,SMARCD3,RBM34,VGF,SPHK2,REEP1,DNALI1,GDPD5,JPH3" Drug 3055_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "RALGAPA1,NDRG2,ATP2B2,LARGE1,NCOR2,CSF1,PDE4DIP,DCAF4,TM9SF4,MAML1,DGKG,KIAA0753,EXOG,SEZ6L2,MRNIP,AGAP2,OGA,GNG4,LILRA2,SPACA9,ATXN2L,OXTR,PDE4A,PDE4D,PPP2R2B,LRRN3,WDR25,ZNF821,FAM102A,SLC2A5,EPN2,TRIM2,KAT6B,TRPS1,XRCC4" Drug 6018_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AGT,AMH,CDC42BPA,APBB2,DNAH17,ADAM23,CFLAR,GYG2,CAMK2G,HOMER3,SIPA1L1,GPRASP1,DTNA,STX2,F5,HTATSF1,CACFD1,INPP5B,LIG4,TAGLN3,NF1,CNOT4,PDE4A,RETREG1,SAMD9,PTN,RGS3,IQSEC2,PHLDB1,ARC,MCF2L,PCDHA5,RIMBP2,XRCC4,HPS4" Drug 6494_DN Proxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,KIF1A,KRIT1,AP4M1,RAB28,AKAP7,FAM169A,DCAF8,DAPK3,DBT,JAKMIP2,ZNF804A,MED12,COQ7,FECH,TRMO,GPR37,GRIK5,MAP4K5,ICA1,MBNL1,MEIS1,LYRM9,TMEM104,ZNF331,FBXO11,SPART,CLASP2,ASTN2,BEX4,TPM1,CLDND1,ZFAND5,RNF170,RNF146" Drug 2958_DN Etomidate [33125-97-2]; Down 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA2A,CASK,MARK4,NUMB,SLC4A4,SCAPER,CD86,CLGN,RAB28,SH2B1,VCAN,SGSM2,EGR3,COQ7,SCML2,PDLIM5,SRCAP,ADAM28,LILRA2,STON1,ZNF862,SETD4,PPP3CC,CEP97,FAM184A,SLC2A5,BTBD3,SIRT2,ZNF667,NSD1,TPM1,SSBP2,UBE3A,EMSY,MARCH8" Drug 4488_UP Amrinone [60719-84-8]; Up 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "DNAH17,SCAPER,HAP1,LDB2,EPS15L1,ABCG2,HOMER3,CNTN1,COL9A3,SH2B1,PDE4DIP,OLFM1,SHISAL1,ITGA7,KHK,LAMA2,KITLG,NPR2,POU6F1,CEP41,PRKAR1B,PTCH1,ELOVL2,PTPRH,PTPRN2,ZSCAN2,FBXW7,ATP8B4,TCP11L1,SH3BP2,DMXL2,SZT2,UBE3A,WIPF1,KCNAB1" Drug 1803_DN Epirizole [18694-40-1]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "CDK10,SEMA4G,MARK4,SCAPER,SCARB1,PLEKHB1,CSF1,RUSC2,PARD6A,SLC12A6,FEM1B,COQ7,VPS26C,SCML2,FGFR1,CINP,CGREF1,SRCAP,FERMT2,GPER1,KIFC3,GIT1,MX1,ZNF862,FA2H,RPS6KA2,MAPK12,ASAP3,FUZ,KDM4D,SIRT2,CAMTA2,LMF1,UPF3A,URM1" Drug 3303_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NME5,ADAM23,ST3GAL5,USP2,CBFA2T2,RAB33A,STOML1,SULT4A1,AKAP7,BAG4,SPOCK2,JAKMIP2,EDNRB,EGFR,F5,ZNF589,GRM8,GSTM5,ICA1,KIFC3,NOVA2,TREM2,PLTP,CEP41,ASAP3,SNCA,KDM4B,ZNF423,ZC3H13,PCDHA6,SLC30A3,NT5M,DNALI1,EVI5,KCNAB1" Drug 6181_DN 2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG3,AGT,APOC1,CASK,NCOA1,BMP7,CAPN3,HIP1R,CD86,SCARB1,SOCS6,RAB33A,CPS1,C2CD2,OSBPL3,PPP1R16B,RASGRP2,CD320,INPP5K,SLC2A6,MUM1,ATXN2L,TJAP1,SMAD1,PTK2,RIPOR1,RET,SEC14L1,MRAS,ARFGAP1,DNMBP,KAT6B,TNS1,PLPPR2,ACTR3B" Drug 2435_UP Bisacodyl [603-50-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADD2,ARRB1,NRP2,SYNJ1,FUBP1,CACNA1I,LARGE1,CNN3,WHRN,NRG2,SEC14L5,SNPH,BRINP1,CDON,SEZ6L2,EIF1,ZNF391,SRCAP,POLL,LILRA2,STON1,KIFC3,AFF1,MMP16,PGAM2,STRN3,WDR25,RASGRF1,SOX15,SYN2,SYT1,TRIM2,LMF1,EVI5,KCNAB1" Drug 3710_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BRAP,APBB2,APC,CDK10,MARK4,EIF4G3,IL33,SRSF11,HOMER3,AKAP7,CRY2,OSBPL3,PDE4DIP,SLITRK5,FBXL5,LYPD1,DMPK,STX2,F8,SEC23B,GAD1,COPS8,GLYR1,GUCY1A1,HAS2,ATXN2L,NFYA,STRN3,PPP5C,CCDC88A,LIMCH1,EXOC7,KIAA1107,TCF4,SMIM8" Drug 3298_DN Cholecalciferol [67-97-0]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA2A,AP2A2,MTUS1,APBB2,BMP7,GYG2,CACNA2D2,PLEKHB1,PLAA,CREM,FAM169A,DTNA,ING4,F8,MSL3,HNMT,IPO5,LIG4,KITLG,NEK1,NF1,CNOT4,SLC11A2,SETD4,CDK18,RETREG1,WDR25,LIMCH1,TSPYL2,TROVE2,ELOVL4,FBXW11,TRIM2,TIAM1,UBE2H" Drug 5859_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASPHD1,NME5,C1QTNF3,DDO,PDE8B,ATP6V0A1,USP2,CBFA2T2,QKI,IPCEF1,TBC1D5,OPTN,PTK2B,DLC1,FGFR1,OGA,DISC1,GPR37,TJAP1,PLCD1,LRRN3,MAPK7,PTPRH,ENOX1,GAL3ST4,KLHDC8A,SEMA6D,ZFP30,ASAP3,DZIP1,CEP68,SLC19A3,HIF3A,RUNDC3B,WNT7A" Drug 6897_DN NS-398; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,AP2A2,BIN1,CDC42BPA,FAM131A,ARRB1,CAMK2B,CLGN,CRLF1,STOML1,LRIG1,DBN1,FBXL5,STX2,FGFR1,USP19,GLYR1,KCNF1,MAP4,NEK1,PLCD1,MINDY2,MAPK7,C1orf54,ZDHHC14,SH3BP2,FRMPD1,PREX2,LIMCH1,ARHGAP26,IQSEC2,SUPT5H,TRIM2,TK2,ZBTB14" Drug 7411_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APC,CDK10,BMP7,CAMK2G,ARHGEF1,STOML1,IQCK,COL4A5,PDE4DIP,DAPK3,FBXL5,PARD6A,DTNA,TRMO,CINP,CGREF1,MALT1,GRB10,MAP4,PLXNB1,SAFB,ANKRD6,PEX26,PPP4R3A,RCOR3,LHPP,SS18,COBL,ANKRD28,BEX4,METTL3,VAV1,NDRG4,SEMA3B,ST7" Drug 2285_DN Nifenazone [2139-47-1]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "RALGAPA1,PPP4R4,CDK13,SYNJ2,CA4,TPP1,CRY2,TBC1D5,ARMCX2,FBXL5,RCAN1,DTNA,PLXNC1,FGF12,FHL1,SRCAP,GLYR1,TDRKH,ICA1,IPO5,KITLG,NFYA,CNOT4,PPP2R2B,CCDC25,SBF1,SS18,PLCB1,PCDHA6,PARD3,ZNF24,TFIP11,SLC30A3,HPS4,EPM2A" Drug 5536_DN Scoulerine [6451-73-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AP2A2,APC,EPB41L5,NECTIN3,CSNK1E,PDE4DIP,DCAF8,ZNF337,GIT2,MFAP3L,DPH1,EGFR,IRAK4,ANKMY1,SEMA4D,TRMO,PRELID3A,TRAF3IP2,SPACA9,RNFT2,MIA2,GIT1,LRP12,POLG,RGS12,SBF1,PEX26,PPP4R3A,SLC22A4,RCOR3,SPART,EXOC7,SLC44A1,PIK3R5,CLDND1" Drug 6221_UP Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AK2,ADGRF5,PLA2G4C,CFAP410,ABI3BP,NCOR2,PDE4DIP,DBN1,DMPK,EPB41L2,VPS26C,PRELID3A,GAD1,HTATSF1,TDRKH,HSF2,KHK,PLTP,PPP2R2B,TMEM104,PTCH1,GSTCD,RCOR3,CDK19,ZBTB43,LHPP,CEP68,PHLDB1,KIAA0930,AP4E1,TK2,TMPO,CLDND1,MAP3K12,GDPD5" Drug 3621_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AGT,PPFIA3,MARK4,GYG2,CFAP410,CDH2,ABI3BP,CREM,AATK,SPOCK2,DBT,ZNF804A,PARD6A,EDN1,FAM13A,RASGRP2,ERCC2,PIPOX,AFF2,NPR2,NPTX1,SLC11A2,PLCD1,PPARA,RASGRF1,KLHL11,RASA3,FRMPD1,SLC11A1,LIMCH1,ARC,TRIM2,PCDHGA10,ZFPM2,TRO" Drug 1695_UP Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AP2A2,C1QTNF3,ALCAM,ATP6V0A1,CFAP410,CBFA2T2,ARHGAP33,TAOK2,PDE4DIP,GREB1,DCAF8,GIT2,TMCC2,DTNA,EIF4G2,SEMA4D,PRUNE2,TDRKH,TJAP1,IL6ST,MAP4,RETREG1,PLXNB1,PMP22,CARF,EMID1,NMNAT2,ZBTB43,TROVE2,ST5,EXOC7,TRIM2,KAT6B,VIPR2,EPM2A" Drug 3292_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,NME5,APBA2,SEMA4G,CBFA2T2,FOXN3,CNTN1,BAG4,HIPK3,PRRC2B,JAK2,LSS,MIA2,MID1,NPTX2,PLCD1,PPARA,RGS12,EMID1,SBF1,ASAP3,SNCA,KIF13A,TSNAXIP1,RPGRIP1L,SZT2,FAM189A1,AP4E1,HEY1,TNS1,CDK20,TRPM2,KCNK12,SPHK2,DNALI1" Drug 4571_DN Levodopa [59-92-7]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABR,APBB2,MARK4,ADAM15,SCARB1,SYNGR3,TPP1,DAPK3,FBXL5,EGFR,ZNF589,FHL1,ANKFY1,PDLIM5,SYT17,MAP4K5,AGFG1,FAM69A,LIG4,MT1M,LYRM9,NF1,LRP12,ASAP3,SS18,NXT2,SYPL1,ASTN2,PDLIM2,KIAA1107,TRIM2,TNS1,TSN,SSBP2,LAT2" Drug 6125_DN Leucomisine [17946-87-1]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,N4BP2L1,BACH1,SGCE,SH2B1,CSF1,PPP1R16B,SGSM2,ENO2,ZNF589,ANKFY1,ERAP1,INPP5K,ZNF276,GLYR1,LILRA2,IL6ST,LIG4,MIA2,PDE4D,CCSER2,RETREG1,STRN3,PILRA,PTPRO,MRPS18A,ZNF821,SUPT20H,FAM214B,SLC11A1,FBXW11,PARD3,KCNAB1,UBE3B,PHTF2" Drug 4266_DN Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "KRIT1,SRSF11,CREM,PDE4DIP,SPOCK3,ING4,ATP2C1,FYN,TRAF3IP2,CRCP,SPIN1,PCLO,AGFG1,IL6ST,MAP4,TM6SF1,NFIX,CNOT4,PDE1C,STRN3,PTN,RAD51D,SLC25A36,FBXO11,PBLD,THSD1,ZC3H4,TCF4,TRIM2,DICER1,TMPO,TFIP11,EVI5,MPPE1,FXR1" Drug 2267_DN Flufenamic acid [530-78-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BIN1,APBB2,BCAS1,ATP6V0A1,SYNJ1,RCBTB2,GREB1,TOM1,PHF20L1,PLXNC1,TPK1,DISC1,GCNT2,TXNL4A,GLYR1,GNG4,TDRKH,GRIK5,ELOVL5,DHX35,INPP1,ITPKB,PLCD1,POLG,PPP5C,PTN,ZDHHC14,RGS12,KLHDC8A,TCP11L1,ZNF821,EXOC7,THRA,KCNK12,SLC30A3" Drug 6240_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADD1,BRAP,MTUS1,CDC42BPA,PKP4,KRIT1,ZMYM4,DCAF8,ZNF337,INTS1,GIT2,RACK1,SEMA4D,PDLIM5,CGREF1,ZNF276,MIA2,PMP22,PPP5C,PRKACB,PTK2,REV3L,ROBO1,AMBRA1,PEX26,ELMO2,SMARCC2,KDM4B,SPATA7,SS18,AGTPBP1,ZNF106,TIAM1,VAV1,CLDND1" Drug 4766_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "SLC4A4,SCAPER,CA4,CAMK2G,ARHGEF2,TAOK2,STOML1,CRY2,CNTNAP2,RIMS2,CNNM1,EGFR,AGAP2,SEMA4D,SRCAP,USP19,PCLO,INPP1,KCNF1,MEF2C,MID1,SMIM7,KCTD17,ZFHX4,ZNF821,PEX26,FAM214B,CCDC88A,ZNF423,THSD1,ARHGEF9,PLCB1,DICER1,THRA,SEMA3B" Drug 141_UP chlorpropamide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,GYG2,CACNA1I,CHRNA4,TAOK2,IQCK,PCYT1B,AATK,RIMS2,DAPK3,PHF20L1,SUGP2,F8,AGAP2,AFF2,PCDH17,RUNDC3A,MCHR1,SOX21,NXPH3,KIF5A,MAN2A2,MYT1,PCDH9,PLEC,PRKAR1B,NEK11,SMARCC2,CLSTN2,HIF3A,THRA,TP53BP1,RPRM,GDPD5,MPPE1" Drug 2716_DN Hecogenin [467-55-0]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADRA1D,AMPD3,PPP4R4,LDLRAD4,TAOK2,NRG2,SUSD5,USP6NL,MFAP3L,DTNA,MTSS1L,PCYOX1,AGAP2,KHDRBS3,GPR75,GPD2,LPAR4,GRM8,LSS,MAP4,MEF2C,AFDN,CNOT4,PTN,GALNT10,FAM102A,ZNF667,KDM4B,SPTAN1,DDN,CRTC1,TK2,MAP3K12,KCNAB1,TIGD6" Drug 6483_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASPHD1,ADCY6,PDE8B,CFAP410,CBLN1,CLGN,WHRN,RIMS2,DAPK1,MFAP3L,RCAN1,EDNRB,FCF1,ELN,DLC1,ANKFY1,DCTN2,FYB1,ICA1,KIT,NFYA,PALM,SLC25A23,PRKAR1B,KCTD17,CCDC25,RPS6KA2,PPP4R3A,PLCB1,SYP,HIF3A,TLR4,XRCC4,SLC30A3,PHTF2" Drug 3336_DN Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "LTBP4,AMT,APBA2,CDK10,MARK4,MPDZ,SCARB1,HOMER3,CNTN1,CRY2,GREB1,DAPK3,DTNA,MRNIP,SRCAP,USP19,GRB10,KHK,CNOT4,CDK18,PLCD1,PRKAR1B,RGS12,GSTCD,SH3BP2,SYBU,ABLIM3,BTBD7,SPTAN1,MCF2L,CRTC1,CDK20,LMF1,KCNK12,HPS4" Drug 2170_DN Solasodine [126-17-0]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADRA1D,MTUS1,AMPD3,APAF1,APOC1,NCOA1,ATP2A2,KIF1A,AP4M1,LARGE1,FOXN3,ZNF337,DGKG,DBT,OPTN,EIF1,F5,FGFR1,SRCAP,GRIK5,IPO5,MYT1,CEP41,RIPOR1,FNDC3A,LIMS2,SLC11A1,BTBD7,IZUMO4,PCDHGA10,THRA,VSNL1,MKRN3,MPPE1,SENP7" Drug 3239_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,ADORA1,BIN1,APBB2,MARK4,CFAP410,KYAT1,TAOK2,QKI,WHRN,FEM1B,EIF4G2,IRAK4,BAIAP2,SEPT9,GRIK5,RNFT2,LMO2,MATK,MGAT3,SAMD9,C1orf54,EMID1,ZNF821,FNDC3A,NLGN1,PKNOX2,KDM4C,ZBTB43,STX1A,TNS2,TK2,ZKSCAN5,WIPF1,REEP1" Drug 3683_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMT,PKP4,APC,APOC1,CDK13,SLC4A4,CFLAR,HAP1,CCNT1,ARHGEF2,PICK1,IQCK,DAPK3,IRAK4,ZNF589,TPK1,INPP5K,LIG4,MBD1,SAMD9,RAD51D,NEK11,ZFP30,DZIP1,PREX2,PPP4R3A,ARHGEF40,CCDC88A,KDM4C,SPTAN1,NXT2,ASTN2,CHST8,RPRM,TFIP11" Drug 2204_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "BIN1,KCNAB2,BCAS1,BMP7,C5,SLC16A4,CBFA2T2,PLAA,RAB26,ABCG1,VCAN,PDE4DIP,SV2B,EXOG,ELN,VPS13B,NCALD,PDLIM5,MBP,MEF2C,OPRL1,SLC25A23,POU6F1,PRKAR1B,PRPH,PTPRN2,SNCA,ST5,CHST8,FLRT2,XRCC4,PRDM10,HPS4,SLC17A7,NLRP3" Drug 2366_UP Ethisterone [434-03-7]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,PPP4R4,KIF1A,MPDZ,BMP7,CDH2,NRG2,VCAN,ZFYVE16,ZNF337,RCAN1,SEZ6L2,HEYL,MTSS1L,ERAP1,SIGLEC8,POLL,GNAL,LPAR4,AFF1,NF1,NNAT,P2RX7,GPR173,FSD1,PPARA,MRAS,SLC11A1,KDM4C,EXOC7,SZT2,TK2,TPM1,SSBP2,VGF" Drug 4714_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APC,NCOA1,ARHGEF2,SOCS6,PDE4DIP,BRINP1,JAKMIP2,ZNF804A,DTNA,HSD17B14,ENO2,SCML2,ST3GAL6,ZNF589,FYB1,SEPT9,INPP5K,GRM8,HNMT,HSF2,KPNA5,MPP2,LRP12,SAMD9,ZSCAN32,PEX26,SPTAN1,TROVE2,NXT2,ZEB1,THRA,TRIO,FAM155A,EVI5,TIGD6" Drug 7405_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,BIN1,PPFIA3,MARK4,ADGRB2,CFLAR,TAOK2,BAG4,ENTPD4,SH2B1,CRY2,GIT2,ING4,MRNIP,RASGRP2,NCALD,ZNF589,SRCAP,GFER,KCNN1,KIF5A,MBD1,MSI1,ADAM22,SLC11A2,PALM,GPR85,TRIM68,EPN2,SLC11A1,LIMCH1,ARHGAP26,THSD1,PARD3,PIK3R5" Drug 3748_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AK2,DOC2A,GAS7,ARRB2,MYRF,TPP1,STOML1,DCTN1,TOM1,ZNF589,GCNT2,ZNF276,SCIN,INPP5B,MAP4,NEK1,PDE4D,NLE1,SLC25A23,SAMD9,ACSS3,FAM184A,FNDC3A,SLC4A3,CCDC88A,ELMO2,SMARCA4,ZEB1,RPGRIP1L,CHST8,TMPO,TRIO,VLDLR,SPHK2,NT5M" Drug 5752_DN Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,ALK,CRLF1,ENTPD4,MFAP3L,FGF1,BAIAP2,CGREF1,GPD2,TDRKH,HSF2,IFI16,NF1,CLDN11,RAD51D,KCTD17,SUGCT,RPS6KA2,SBF1,ATXN7,SH3BP2,KIF16B,KBTBD4,SLC14A1,BTBD7,IFT122,SNCA,ZNF415,ZBTB43,SS18,COBL,FBXW11,CHST8,VGF,PHTF2" Drug 5637_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABR,ASPHD1,NDRG2,GAS7,CDC14B,ARHGDIG,CDK13,ATP6V0A1,CAMK2B,KCNAB3,EPS15L1,ARHGAP24,SPOCK2,CHRDL1,DMPK,PLXNC1,FGF13,FOLR2,GAD1,KHK,TAGLN3,MYCN,PDE4A,PLCD1,SH3BP2,SLC6A8,SLC8A1,SNCA,IZUMO4,TBL1X,PDIA2,XRCC4,SLC30A3,EVI5,KCNAB1" Drug 4540_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "MTUS1,CDC14B,CDK10,ZSCAN18,GYG2,CACNA1G,RUNX1T1,SCARB1,CRLF1,ASIC3,CHN2,SULT4A1,CDON,EGFR,MBNL2,ING4,ETV1,REEP2,DCTN2,ERAP1,GFER,SHISAL1,KCNJ5,ENPP2,PPP2R2B,RASGRF1,BEND5,GAL3ST4,KCTD17,MRAS,ZSWIM8,RBM26,SYT1,TACR1,TRIM2" Drug 3723_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,CDK13,ALDH7A1,MYRF,RCBTB2,PLAA,QKI,CPS1,HAPLN1,NCOR2,DAPK3,DTNA,FCF1,ING4,TUBD1,ETV1,VPS26C,PTK2B,ERAP1,GLUL,INPP5B,MMP16,CNOT4,PFKFB2,MINDY2,CEP41,PRKAR1B,CLIP1,CSRNP3,ZHX3,TROVE2,ELOVL4,TMPO,TRIO,REEP1" Drug 1217_UP chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "PDE8B,CACNA1I,CACNA2D1,AKAP7,HAPLN1,PHF14,DAPK3,SPOCK3,DPH1,RCAN1,EGFR,STX2,AFF2,ALDH1L1,GNAO1,STON1,SOX21,SHISAL1,MAP4,GIT1,ZNF862,NF1,CNOT4,POLG,SH3TC2,RNASE1,NUDT11,FNDC3A,TSNAXIP1,ARHGAP26,NR2C2,TRIO,UGT8,XRCC4,SH3GLB2" Drug 3335_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA2A,KCNAB2,APLP1,CA4,CA12,FAM189A2,CREM,CRY2,FAM169A,USP6NL,TBC1D5,MAML1,ARMCX2,SGSM2,EIF5,STX2,SEMA4D,PDLIM5,GALC,SEPT9,GRB10,ICA1,INPP5B,ITPKB,IPO5,MAP4,SLC25A23,PRKAR1B,ZNF821,IQSEC2,PLCB1,SMG6,VIPR2,EVI5,HPS4" Drug 1515_DN Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "DOC2A,ARRB1,SLC4A4,CFLAR,RAB29,HOMER3,CRY2,DCAF8,DMPK,SUGP2,ACSL4,GLYR1,CNTRL,TJAP1,MPP2,SETD4,PIK3R1,NLE1,MBOAT7,PTPRE,MSANTD2,RNASEL,TCP11L1,SBF1,SEC14L1,FUZ,FBXO11,KDM4B,ELOVL4,ASTN2,TBL1X,AP4E1,PARD3,LMF1,ACTR3B" Drug 7491_UP CP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,CDC14B,C5,CBFA2T2,ASIC3,QKI,RAB26,AKAP7,ARMC8,CTH,CDKL3,BAIAP2,TRMO,CINP,CGREF1,DENND2A,MSL3,KCTD15,SAMD9,TMEM231,FAM184A,GSTCD,SBF1,KDM4C,SS18,SZT2,HIRA,UBE2H,UGT8,WIPF1,TRIM9,MAP3K12,EMSY,ST7,UBE3B" Drug 4693_DN Kawain [500-64-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,RGS20,KIF1A,ARHGEF2,LHX2,AKAP7,SLC4A8,ARHGEF4,PPP6R2,BRINP1,RUSC2,DNM1,DTNA,AASS,FHL1,SEPT9,MSL3,GNG4,GRM8,MAP4,NPTX1,MAPK7,TRAPPC13,SH3BP2,FUZ,KIF13A,TROVE2,ZEB1,THRA,TSC1,VGF,XRCC4,DNALI1,EVI5,KCNAB1" Drug 7066_UP SB 203580; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APBB2,CDK13,MARCH3,NCOA1,SCAPER,ENTPD4,SH2B1,VCAN,EDIL3,FAM13A,EGFR,FGFR1,SCARA3,OGA,FYB1,FYN,DENND2A,USP19,KCNMB4,FICD,SLC2A6,MIA2,SCAMP5,TAGLN3,PLXNB1,MAPK7,FAM184A,ZFP30,FUZ,KIF13A,SPTAN1,ZBTB43,DNMBP,TNS1,MAP3K12" Drug 6175_DN LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,ABHD6,APAF1,C5,EPS15L1,RCHY1,C2CD2,SH2B1,APPL1,B3GAT3,KIAA0753,SGSM2,NR1D2,DTNA,FAM13A,ING4,COQ7,ANKMY1,SRCAP,COPS8,GLYR1,PRRC2B,ATXN2L,TJAP1,RGS3,PLPPR3,FBXO11,DZIP1,SIRT2,TACC1,ZKSCAN5,HIRA,LAT2,ZNF32,FIP1L1" Drug 1408_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,APBB2,ARRB2,PDE8B,RGS11,BMP7,SYNJ2,CACNA1I,LDLRAD4,RUNX1T1,CD86,RAB26,CRYM,ARHGEF10,ING4,KAT8,PRKAG2,FHL1,FLNC,EFCAB2,ATP2C1,ALDH1L1,SRCAP,PCDH17,GPR12,NELL2,NF1,POLG,CRTAC1,TCP11L1,FBXO11,SLC2A5,SYT1,CDH22,TK2" Drug 7202_DN Glibenclamide [10238-21-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AP2A2,MAP4K3,PPFIA3,BACH1,CBFA2T2,SCARB1,TAOK2,QKI,ABCG1,PDE4DIP,DZIP3,PARD6A,SUGP2,EGR3,COQ7,VPS26C,EZH1,PRKAG2,TXNL4A,COPS8,MAP4,MBD1,SLC25A23,SMIM7,RIPOR1,FBXW7,CLASP2,CAMTA2,ELOVL4,EXOC7,METTL3,ZNF23,MAP3K12,MPPE1,EPM2A" Drug 7130_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AK2,APC,SLC4A4,B4GALT6,ARHGAP32,SPATA2,TNK2,HSD17B14,ERBB2,SCML2,POMT1,DENND2A,DISC1,COPS8,PRRC2B,HNMT,IL6R,MAN2A2,NFYA,CNOT4,RGS4,KIRREL1,SBF1,ATXN7,PBLD,DIP2A,STX1A,ARHGEF9,NSD1,FAM155A,UBE3A,BCL2L13,LMF1,MAP3K12,ACTR3B" Drug 7429_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADCY6,OSBPL1A,APOC1,MPDZ,BCL7A,C5,B4GALT6,CSNK1E,KIAA0586,DMPK,SEPT9,SRCAP,IPO5,PCDH9,PLEC,SMIM7,PLXNB1,CEP97,RGS3,MAP6D1,SH3BP2,EPN2,CDK5RAP2,RCOR3,PBLD,CEP68,MCF2L,EXOC7,ZKSCAN5,HIRA,PLPPR2,ZNF45,ZNF142,UBE3B,GAN" Drug 576_UP "novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMPD3,APAF1,APOC1,PRX,ADAM23,C5,KALRN,HAP1,KCNAB3,DLGAP1,CHN2,PICK1,OSBPL3,DMD,ETV1,PTK2B,NSG1,DISC1,GUCY1A1,KCNJ5,SAMD14,NCF2,NTRK3,OPRL1,PDE1C,PLCD1,LRRN3,C1orf54,BEND5,RNASE1,SNCA,SPART,PHF24,CLIP2,SLC17A7" Drug 5776_UP Hexestrol [84-16-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ASIC1,LTBP4,BEGAIN,EPB41L5,KIF1A,ADAM23,RGS11,NRP2,ST3GAL5,BAIAP3,DLGAP1,WHRN,CRY2,CSNK1E,RIPOR2,PDLIM5,ALDH1L1,PRUNE2,ADAMTS13,PADI2,ICA1,KCNB1,RETREG1,POU6F1,RASGRF1,KCTD17,STUM,HKDC1,SNCA,SPTB,ARC,DOCK9,CA14,WIPF1,MAP3K12" Drug 3180_DN Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "TRMT9B,CDC42BPA,FAM131A,MARCH3,MARK4,ATP2A2,ATP6V0A1,CFLAR,SCAPER,CFAP410,PLEKHB1,TAOK2,BAG4,TOM1,EDNRA,CDKL3,ZNF44,GALC,ERAP1,POLL,GNG4,FERMT2,HNMT,INPP5B,KCNF1,TMEM104,PTPRG,RGS12,RPS6KA2,SBF1,SOX3,THSD1,EXOC7,TRIM2,VIPR2" Drug 994_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "CDK10,CFLAR,NAE1,EPS15L1,RAB28,CLTB,CSNK1E,CTH,DBT,FBXL5,PARD6A,SGSM2,MED12,FEM1B,DENND4A,KAT8,SEC24B,ATP2C1,INPP5K,MUM1,DHX35,MKLN1,NLE1,PLEC,PMP22,RETREG2,PPP3CA,NKAIN1,MAPK12,ZFP30,ZBTB43,TACC1,KAT6B,UBTF,ST7" Drug 427_DN iloprost; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,ARRB1,PDE8B,ADAM23,ADAM15,ARHGEF7,HAP1,ARHGEF2,PICK1,CNTN1,DAPK1,TOM1,EPB41L2,NEU3,RUNDC3A,MCHR1,PTPRT,NXPH3,CCSER2,MAPK10,SH3BP2,SH3GL3,SLC2A5,PKNOX2,ELMO2,KDM4B,NMNAT2,CDK19,PLCB1,CHST5,TRIO,ZIC1,VPS35L,SLC17A7,EPM2A" Drug 4575_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "PKP4,APC,FAM131A,CACNA1A,PLAA,CSF1R,ARHGEF10,PDE4DIP,CDON,FEM1B,EZH1,FGFR1,SCARA3,FYB1,ERAP1,SYT17,SHISAL1,KHK,SCAMP5,LYRM9,NDP,FA2H,FNDC3A,ZNF334,BTBD7,SPTAN1,ARHGEF9,ASTN2,TCF4,CRTC1,ZNF32,NT5M,EVI5,KCNAB1,PHTF2" Drug 1013_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "APOC1,PPFIA3,ARHGDIG,PDE8B,SYNJ2,MTMR3,ARHGEF2,TAOK2,LRIG1,PDE4DIP,ARHGEF4,DBN1,LYPD1,VPS13B,ZNF589,AFF2,SEPT9,SRCAP,COPS8,KPNA5,MPP2,FA2H,PRKAR1B,TCP11L1,SCN8A,KDM4B,ZHX3,SPART,CLSTN2,THSD1,SMG6,WSCD1,ZNF34,CDK20,VGF" Drug 5814_DN (R)-Propranolol hydrochloride [13071-11-9]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "MADD,MPDZ,CAMK2G,CCNT1,LRRFIP1,RAB28,CSF1,SIPA1L1,DZIP3,PPP6R2,ZFYVE16,RHOBTB1,MAMLD1,ACSL4,GSN,DHX35,IL6R,MAP4,MEIS1,ZNF862,NFIX,PLCD1,MAPK7,SAMD9,MCMBP,PEX26,ZNF430,INTS9,POGZ,SEPT8,SLC35G2,ZNF34,BHLHB9,TRIM9,NAV3" Drug 6773_DN Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ABHD6,ALCAM,APC,BCAS1,NUMB,SLC4A4,BMP7,CBFA2T2,MAGI1,B4GALT6,NCOR1,PDE4DIP,GPRASP1,DCAF8,EDNRA,ANKMY1,ZNF589,SEMA4D,CGREF1,MATK,ADAM22,SLC11A2,RETREG1,SLC25A23,PRPH,ZNF821,EPN2,LIMCH1,UNC5B,KIAA0930,TPM1,CDK20,ZKSCAN5,EPM2A,UBE3B" Drug 6126_UP Natamycin [7681-93-8]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "FAM135A,APBB2,ADGRB2,PROM1,MYRF,LDLRAD4,HAP1,CCK,SOCS6,SLIT2,NRG2,ARHGEF10,RIMS2,HEYL,OPTN,SRPK3,EIF1,STON1,KCNB1,SMAD1,PPP2R2B,WDR25,RFX2,RGS4,PNMA8A,ASAP3,CXXC4,ARHGAP26,SPTAN1,ASTN2,MTCL1,EXOC7,TBCEL,SPHK2,SLC17A7" Drug 5447_UP Isradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,ALK,BIN1,MYRF,LDLRAD4,TAOK2,CLTB,PICK1,GREB1,SLC12A6,ING4,VPS26C,DLC1,ERAP1,ICA1,TJAP1,KCNB1,PACRG,MAP4,MAPT,LRP1B,NF1,PTPRH,RGS12,CNKSR2,ZHX3,SPTB,TROVE2,JMJD6,WSCD1,CRTC1,CHST8,CHST5,NT5M,AP3B2" Drug 2941_DN 3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,KIF1A,FUBP1,CFAP410,KRIT1,SLC16A4,FOXN3,SOCS6,LHX2,DGKG,B3GAT3,RASGRP2,SCML2,PADI2,MAP4,MEF2C,MX1,PDE4A,CCSER2,PLCL1,STRN3,ZSCAN32,ZNF493,ATXN2,GALNT10,ANKRD6,KBTBD4,ZNF667,KDM4C,TSPYL2,SEPT8,AP4E1,FLRT2,MAP3K12,FZD3" Drug 1385_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ALCAM,CFLAR,PCYT1B,PPP6R2,DCAF8,ZNF337,INTS1,DPYSL2,EGR3,RASGRP2,VPS26C,EZH1,FHL1,SRCAP,PADI2,IPO5,MBD1,NF1,ENPP2,TRHDE,LRP12,MBOAT7,CNNM2,PTK2,SLC25A36,FBXW7,SGK1,ARHGEF40,MAPKBP1,SPP1,ANKRD12,TBL1X,CBX5,CA14,MPPE1" Drug 3457_UP Hecogenin [467-55-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "ADORA1,AP2A2,AK2,ARHGDIG,MARK4,KSR1,MTMR7,COL9A3,SIPA1L1,ARHGEF4,KLHL3,EXOG,C3orf18,FGFR1,SCARA3,PCDH17,STON1,GSTM5,MAPT,LRRN3,PPP5C,PRODH,RGS3,RGS4,ROBO1,ASAP3,PREX2,SNCA,KDM4C,EXOC7,KIAA0930,DICER1,OSBP2,REEP1,EMSY" Drug 1658_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NCOA1,BMP7,SYNJ2,MTMR2,QKI,PPP6R2,GPRASP1,MAML1,GIT2,DTNA,MBNL2,IRAK4,COQ7,CDKL3,F8,FGFR1,ANKFY1,INPP5K,GPR37,KIF2A,MAP4,SETD4,SLC25A23,PRKACB,ZNF331,PEX26,EPN2,BTBD7,TSPYL2,PBLD,ANKRD12,SMUG1,WRN,XRCC4,MPPE1" Drug 3849_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NDRG2,ADRA1D,ARRB1,ATP6V0A1,BAIAP3,CALB2,HAP1,CAMK2B,CBFA2T2,TAOK2,BAG4,ARHGEF10,DAPK3,GIT2,DTNA,MBNL2,CDKL3,PCLO,IL6ST,NPR2,PCDH9,RETREG1,PLCD1,STRN3,MINDY2,PPP5C,CNNM2,SNRK,ZSCAN32,RGS12,BTBD7,SYN2,RUNDC3B,ZFP37,KCNAB1" Drug 5616_DN Enoxacin [74011-58-8]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "NME5,GAS7,BCAS1,GYG2,CFAP410,CBFA2T2,TPP1,HOMER3,AKAP7,ABI3BP,SH2B1,CSNK1E,PDE4DIP,MED12,RCAN1,ING4,MRNIP,GAA,RASSF8,ICA1,CNOT4,NPTX1,SETD4,PRODH,RPS6KA2,AMBRA1,BTBD7,KDM4B,ARHGAP26,ELOVL4,DMXL2,KIAA0930,TNS2,CABIN1,HPS4" Drug 4955_DN Carisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 35 197 "AMT,CDK10,KRIT1,FAM189A2,QKI,AKAP7,ARHGAP32,ARMCX2,DTNA,CDKL3,EZH1,OLFM1,HTATSF1,CACFD1,HNMT,MAP4,ZNF862,NEK1,NPR2,PIK3R1,PLCD1,STRN3,PRODH,PRPH,WDR25,ZCWPW1,TRAPPC13,SPTAN1,CEP68,PRRC2C,ARHGEF9,RPGRIP1L,KAT6B,REEP1,MPPE1" Drug 410_UP 2-propylpentanoic acid; Up 200; 10000uM; HL60; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "FAM131A,MARK4,ATP6V0A1,SYNJ1,SCAPER,WASF1,CLCN3,TMEM184B,RUBCN,SPATA2,C2CD2L,MRNIP,ENO2,FGFR1,PCYOX1,FYN,RAB40B,GRIK5,SERPINI1,CCSER2,GPSM2,MAPK9,RPS6KA2,ELMO2,ZSWIM8,TSPYL2,STX1A,STXBP1,PLPPR2,CLIP2,KLC2,REEP1,FIP1L1,MPPE1" Drug 1286_UP Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "NDRG3,MTUS1,CDK10,CLGN,SOCS6,QKI,SLITRK5,DBT,RCAN1,HIPK3,FCF1,FAM13A,EIF5,COQ7,ELOVL5,HSF2,NFYA,CCSER2,MINDY2,CNTLN,SH3BP2,PPP4R3A,NXT2,SYPL1,FBXW11,TLR4,ELP5,TSN,ZNF24,ZNF45,TFIP11,EMSY,RNF146,SENP7" Drug 4421_DN Lidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "AMPD3,APC,ATP2A2,CFLAR,HAP1,CAMK2B,CACNA2D2,SPOCK2,OPTN,HSD17B14,ERCC2,OGA,ALDH1L1,GCNT2,RUNDC3A,ICA1,IL6ST,ADAM22,CNOT4,ZNF821,FAM214B,PKNOX2,CCDC88A,SLC9A5,SLC11A1,KDM4B,PDZD2,IQSEC2,RBM26,TBL1X,R3HDM1,TPM2,TRIO,HIRA" Drug 3165_UP Retinoic acid [302-79-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "AMT,OGT,APBA2,GAS7,CDK13,ADAM23,CA4,CAST,RUNX1T1,LY86,SLC4A8,CSF1,KLHL3,C3orf18,FLT1,SOX21,PFKFB3,PTPRH,SCN2B,SLC8A1,SLC22A4,FAIM2,HECW1,PLCB1,TRIM2,PCDHGB6,TRIO,VSNL1,WIPF1,MKRN3,GDPD5,PRDM10,SEMA3B,HRASLS" Drug 460_UP deferoxamine mesylate salt; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "APAF1,AZGP1,BACH1,BAIAP3,SEPT7,KCNAB3,CRMP1,RASSF2,FAM13A,ENO2,STX2,ERCC2,BAIAP2,TMEM8B,INPP5K,LILRA2,GPER1,AFF1,NEK1,PFKFB3,PFKFB4,FXYD1,PTPRN2,PTX3,SLC11A1,SNAP25,KDM3A,TACC1,MCF2L,DMXL2,ZEB1,OBSL1,TNS1,TRPS1" Drug 6429_UP F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "BIN1,CDC42BPA,PPFIA3,MARCH3,ARHGEF7,BAIAP3,CA12,CDH2,CREM,CRY2,CSNK1E,TBC1D5,RRAGB,PRELID3A,FYN,ZNF276,MAP4K5,IL6ST,MBD1,MIA2,MMP16,NFE2L2,ELOVL2,GAL3ST4,HSPA4L,UNC5B,TSPYL2,SATB2,HIRA,UBE2H,MPPE1,EPM2A,ST7,PHTF2" Drug 7439_DN Disopyramide [3737-09-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.85E-03 1.00E+00 2.83E-02 3.19E-01 34 190 "MTUS1,NCOA1,STX16,RIPK1,SPAG9,SOCS6,TAOK2,QKI,DAPK3,DBT,DTNA,FCF1,GPHN,ANKFY1,GLYR1,HSF2,MBNL1,NF1,NFYA,PIK3R1,CCSER2,PLXNB1,PPP5C,TCP11L1,CLIP1,FERMT1,ELMO2,SS18,NXT2,CEP68,SYPL1,FBXW11,XRCC4,ZNF45" Drug CID000000051 alpha-ketoglutarate Stitch 4.88E-03 1.00E+00 2.85E-02 3.21E-01 43 254 "SEMA6A,BBOX1,ATP1A3,SLC25A14,KYAT1,CDO1,CS,PHC2,AASS,PRKAG2,ATP5PD,TPK1,DOT1L,GAD1,GATM,GCK,GPR162,GLUL,CBX1,GPT2,GPD1,GPD2,IDH3A,IDH3B,KCNK3,KHK,NPTX1,PKM,PSAT1,PRODH,APTX,TMLHE,OGDHL,KDM4B,KDM3A,CLSTN2,ADHFE1,JMJD6,SYT1,SLC19A3,TP53BP1,SLC17A7,JMJD1C" Drug CID000000923 sodium Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 133 944 "ASIC1,METAP1D,ADCY5,ADCY6,ADCY8,ADD1,SLC24A4,AGT,ANK2,PHF12,KCNAB2,ATP1A1,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B2,SLC2A11,ALDH7A1,BCHE,HCN2,BLM,NAE1,CA4,CA12,CACNA2D1,CALM1,KYAT1,CCK,KRIT1,P2RX6,ENTPD2,LRBA,ASIC3,CHN1,CHRNA4,CLCN3,SLC4A8,CRYM,CNTNAP2,PYGO1,DCTN1,SACS,DMPK,SLC29A4,SLC12A6,DTNB,EDN1,EDN3,SLC43A2,ERBB2,PIPOX,PTK2B,SCML2,SLC9B2,ATP6V1H,ATP2C1,GABRA3,GABRB3,GABRG1,GABRG2,GATM,GCK,DHRS4,POLL,KCNMB4,LNX1,MCHR1,GRIA2,GRIK4,GRIK5,CIT,KAT7,HMGCR,IGF1,IL12A,KCNB1,KCND2,KCNH2,KCNJ5,KCNJ16,KCNK3,KCNN1,KCNN2,KCNN3,LIG4,FXYD7,NBL1,P2RX7,ENPP2,PKD1,PKM,PLCB2,FXYD1,PRKACB,PRKCB,SLC26A11,GDPD1,PTPRB,PTPRG,RDX,RPL15,GLDN,RYR3,SCN2B,SCN7A,SGK1,SLC4A3,SLC2A5,SLC6A11,SLC8A1,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC22A4,HECW1,SPP1,PEG10,SST,TACR1,ACTR6,NPL,NR2C2,TRPM2,SGK3,UBE2H,KCNT2,SLC38A1,SLC17A7,KCNAB1,WNK3,ST8SIA2" Drug CID004346372 AC1N8N2J Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "GAD1,GRIA2,GRIK4,GRIK5,SYNPO,MAP4,PTCH1" Drug CID000004593 olprinone Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "ADRB2,ARHGDIG,ALDH7A1,EDN1,TNFAIP8L3,PDE3A,PDIA2" Drug CID000008346 DnOP Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "APC,APPL1,DMPK,POLK,DLL3,DDN,TP53BP2" Drug CID000064727 lovastatin acid Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "ABCG2,HMGCR,NBL1,ABCB1,PIK3C2A,SYNE2,NETO1" Drug CID004469991 AC1NBLOD Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "APPL1,GAD1,CIT,DDX19B,GPSM2,PTPRN,PTPRN2" Drug CID000148196 diquafosol Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "ADORA2A,P2RY13,P2RY1,PDE4B,PDE4D,S100B,P2RY12" Drug CID000073948 carbohydrazide Stitch 4.90E-03 1.00E+00 2.86E-02 3.22E-01 7 20 "SEMA6A,CHRDL1,SLC29A4,LOXL3,MAP4,P2RX7,RDX" Drug CID000001985 amoebal Stitch 4.92E-03 1.00E+00 2.87E-02 3.24E-01 11 41 "MYH7B,RUNX1T1,RGN,TUBD1,TUBB3,AGAP2,TUBA8,CRCP,TK2,TUBB1,TUBA1A" Drug CID000004426 AC1L1I54 Stitch 4.92E-03 1.00E+00 2.87E-02 3.24E-01 11 41 "ADCY5,ADCY6,ADCY8,CACNA1A,CACNA1B,CACNA2D1,SDCBP2,MCHR1,OPRL1,SSTR1,SSTR2" Drug CID000001927 9-HODE Stitch 4.94E-03 1.00E+00 2.88E-02 3.24E-01 27 142 "ADCY5,ADCY6,ADCY8,ADORA2A,AGT,APC,COL4A5,NCOR1,NCOR2,ABCG1,CSF1,HDAC9,HEPH,E2F5,E2F6,PIPOX,PPARGC1A,GPD1,GPD2,GRIA2,GRIK5,GRM2,PPARA,RXRA,TCF12,SIRT1,NETO1" Drug CID000002783 clenbuterol Stitch 4.94E-03 1.00E+00 2.88E-02 3.24E-01 27 142 "ASIC1,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,MYH7B,ARHGDIG,CAST,ASIC3,MYL6B,CS,GSDME,DMD,IGF1,MEF2C,AFDN,MYH3,MYO5A,MYO6,MYO9A,RPS6KA2,SAFB,SCN7A,MYO18A,PDIA2" Drug CID000444705 TR z Stitch 4.99E-03 1.00E+00 2.91E-02 3.28E-01 8 25 "CBS,AASS,ZMYND10,BVES,ABCB1,S100B,CASC3,TST" Drug CID000011598 diallyl Stitch 4.99E-03 1.00E+00 2.91E-02 3.28E-01 8 25 "SYN3,ADORA2A,CBS,ABCG2,MAPK3,MAPK9,FNDC3A,CLSTN2" Drug CID006918486 Luveniq Stitch 4.99E-03 1.00E+00 2.91E-02 3.28E-01 8 25 "CA4,EDIL3,FGF1,LSS,PPP3CA,PPP3CC,CABIN1,EPM2A" Drug CID000002396 GF109203X Stitch 4.99E-03 1.00E+00 2.91E-02 3.28E-01 55 342 "ADCY5,ADCY6,ADCY8,ADORA1,ADRA1B,AGT,BTK,CACNA1A,CACNA1B,CALM1,ARHGEF1,LRBA,CLCN3,PLCXD3,MAML1,DAPK3,EDN1,EDNRA,EDNRB,EGFR,ERBB4,PTK2B,FOXO3,PLCD4,GRM2,GRM8,MYLK2,KCNH2,STMN1,ASPRV1,NPY,P2RY1,PDPK1,PIK3C2A,PIK3R1,PLCB2,PLCD1,PRKACB,PRKCB,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,PSMA6,PTH1R,PTK2,RGS3,S100B,MAPK12,SLC2A5,PLCB1,TMPO,VLDLR,PLD4" Drug CID000001233 ibotenic acid Stitch 5.00E-03 1.00E+00 2.91E-02 3.28E-01 24 122 "ACHE,BCHE,CA4,CALB1,CCK,CLCN3,PPP1R1B,GAD1,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,MAP4K5,MAP4,KITLG,NPY,GPSM2,POU6F1,SST,SYP,VIPR2" Drug CID000000305 choline Stitch 5.04E-03 1.00E+00 2.93E-02 3.31E-01 52 320 "ACHE,ABHD6,APC,ATP1A1,ATP1A3,ATP1B3,BCHE,CA4,CA8,CA12,CACNA2D1,CALB2,SPAG9,CBS,CHRNA4,PCYT1B,ABCG1,PLCXD3,PNPLA8,HEPH,ENPP6,ST3GAL6,PSD2,GAD1,GPT2,GRIA2,PLCD4,TNFAIP8L3,KCNN1,MAT2A,AQP11,ENPP2,PLCB2,PLTP,PPARA,PTCH1,SMPD3,SEC14L1,SLC6A11,SLC12A4,SLC22A4,DDN,ADHFE1,VPS13A,PLCB1,SYT1,SLC44A1,SMUG1,CA14,SLC30A4,PLD4,GJC2" Drug CID000000948 nitrous oxide Stitch 5.11E-03 1.00E+00 2.98E-02 3.36E-01 20 96 "ATP2A2,ATP2B2,CACNA1I,CBS,AP4M1,TRIM69,APPL1,AASS,ATP2C1,GGT7,GGT5,GUCY1B1,MBP,NBL1,OPRL1,FXYD1,RDX,TNFRSF19,CLSTN2,UBE2H" Drug CID000000761 5'-GMP Na2 Stitch 5.12E-03 1.00E+00 2.98E-02 3.36E-01 54 335 "BRAP,APBB2,CASK,ALDH7A1,CALM1,CCNH,ENTPD6,MAGI1,DLGAP1,MAP4K4,ENTPD4,GDA,DNM1,ABCC5,DNM1L,EDN1,CELSR3,ELN,ERCC2,ETV1,GMPR2,NELFCD,MTHFD2,SEPT9,GRIN2C,GRIN2D,GUCY1A1,GUCY1B1,TNFAIP8L3,IRF8,SMAD1,NPR2,TBC1D25,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,POLR2F,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,RNASE1,S100B,MAPK12,CNKSR2,NMNAT2,SUPT5H,VPS13A,SYNE1,PRTFDC1" Drug CID005469591 NSC-690579 Stitch 5.14E-03 1.00E+00 2.99E-02 3.37E-01 17 77 "BLM,CCNH,CCNT1,CD86,SULT4A1,GDA,ERCC2,ZMYND10,LIG4,NBL1,NTRK3,RNASE1,RNH1,TK2,WRN,PRTFDC1,KAT6A" Drug CID000123395 EDSS Stitch 5.18E-03 1.00E+00 3.00E-02 3.38E-01 25 129 "ACHE,APLP1,APOC1,BCHE,PTBP2,RUNX1T1,CD86,CNR1,CST3,DAPK3,IL12A,LIFR,MAPT,MBP,MX1,NEFH,MAPK9,S100B,TRERF1,SPP1,SYP,TMEM121,NPL,ZIC1,NETO1" Drug CID000446186 1i32 Stitch 5.18E-03 1.00E+00 3.00E-02 3.38E-01 25 129 "CASKIN1,EIF4G3,SYNJ2,SCARB1,EDNRB,MRO,EIF4G1,EIF4G2,EIF1,SRRM1,ERBB2,ADGRV1,FECH,STAU2,RNPS1,TNRC6A,ACOT7,MITF,XRN1,CASC3,STAU1,SMG6,TSC1,TSC2,UPF3A" Drug CID000002519 caffeine Stitch 5.21E-03 1.00E+00 3.00E-02 3.38E-01 84 562 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,PDE8B,ATP2A2,ATP2B2,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CH25H,CCK,KRIT1,P2RX6,LRBA,CACNA2D2,CHRNA4,CNOT8,AKAP6,COX4I1,PHF14,PLCXD3,DMD,EIF1,ENPP6,ERCC2,PPP1R1B,ATP2C1,BRSK1,MSTN,GPR162,CYP46A1,KCNMB4,LPAR4,GRIA2,PLCD4,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,TNFAIP8L3,MYLK2,KCNH2,MARK1,N6AMT1,P2RY13,P2RX7,P2RY1,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PIK3C2A,PKD1,XRN1,PLCB2,PLCD1,PRKACB,GDPD2,QDPR,NEK11,RYR3,MAPK12,SMPD3,SLC4A3,PPP4R3A,NEK4,PLCB1,TPCN2,SYNE1,TK2,P2RY12,ZNF24" Drug CID000064735 LaCl3 Stitch 5.23E-03 1.00E+00 3.00E-02 3.38E-01 12 47 "ADRB2,AMT,ATP2B2,CACNA2D1,CALM1,CCK,KRIT1,RGN,PTK2B,MAP4K5,GSTCD,P2RY12" Drug CID000784625 5-(2-chlorophenyl)-2-furoic acid Stitch 5.23E-03 1.00E+00 3.00E-02 3.38E-01 12 47 "METAP1D,ABCG2,FKTN,GRIK4,NEFM,NEFH,NTRK2,RELN,RDX,SLC12A2,TSC1,TSC2" Drug 873_DN trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 32 177 "PTBP2,KIAA0753,RHOBTB1,EXOG,RASGRP1,EGR3,CHST15,KAT8,AMOTL2,SYNCRIP,TRMO,TRAF3IP2,SPIN1,PRRC2B,SMAD1,CLIP1,RXRA,SCAF8,FERMT1,PPP4R3A,ZC3H4,USP22,TMPO,KAT6B,TRPS1,UBE3A,UBTF,USP1,ZBTB14,ZIC1,PRDM10,ST7" Drug 985_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 32 177 "CDC42BPA,BARD1,CA12,QKI,TBC1D5,NR1D2,RASGRP1,EGR3,EIF4G1,PLEKHA1,DLC1,PCYOX1,CAMKK2,SPIN1,KTN1,MBP,MYO6,PIK3R1,TMEM260,RBBP6,SLC25A36,ZNF430,SMARCA4,MYCBP2,TROVE2,PRRC2C,TBL1X,DICER1,KAT6B,USP1,ZNF24,ZBTB38" Drug 4652_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 32 177 "APC,SHROOM2,NCOA1,BCL7A,SCAPER,QKI,NRG2,SLITRK5,ARHGAP32,TBC1D5,VPS13B,GPHN,SYNCRIP,ANKFY1,DENND2A,HAS2,SYNPO,JAK2,NDP,NFYA,PPP5C,PTK2,TCP11L1,EPN2,SS18,SYT1,MTCL1,DNMBP,FBXW11,NSD1,TK2,PARD3" Drug 5470_DN Roxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,APC,CFLAR,BMP7,AKAP7,PDE4DIP,ARHGAP32,DAPK3,GIT2,SGSM2,EDNRA,FEM1B,CELSR3,ENO2,SCML2,CGREF1,KCNMB4,GNG4,IL6R,JAK2,MAP4,NF1,NTRK2,PLEC,SLC25A23,MRPS18A,SMARCA4,RBM34,SPTAN1,NXT2,PHLDB1,CABIN1,PLPPR2,LMF1,KLC2" Drug 7200_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AP2A2,MTUS1,BIN1,EPB41L5,PPFIA3,ATP6V0A1,ST3GAL5,FOXN3,PICK1,SH2B1,CSNK1E,CTH,GREB1,C2CD2L,PARD6A,MED12,DTNA,EIF4G2,ZNF589,AFF2,OGA,GLYR1,MSL3,BTN2A1,INPP5B,GIT1,ADAM22,NF1,ASAP3,AMBRA1,PEX26,MAPKBP1,ZBTB43,TROVE2,GAN" Drug 6481_DN Nilutamide [63612-50-0]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "TRMT9B,AMH,AMPD3,APBA2,GAS7,PPFIA3,ATP6V0A1,BAIAP3,CAMK2G,CRLF1,B4GALT6,ENTPD4,PDE4DIP,TM9SF4,JAKMIP2,EGFR,MBNL2,PLXNC1,PRELID3A,IL6R,KCNF1,MITF,NFYA,P2RY1,WDR25,ZSCAN32,ZDHHC14,SH3BP2,SLC9A5,ARC,EXOC7,TRIM2,SLC44A1,VIPR2,MPPE1" Drug 5284_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADCY6,AGT,ALCAM,APC,BCAS1,MARK4,NCOA1,SYNJ2,SCAPER,CAMK2B,PDE4DIP,SPOCK2,EIF4G2,BAIAP2,AHDC1,GRIK5,BTN2A1,IL6R,MAP4,PTN,NKAIN1,ZNF821,SH3BP2,FNDC3A,SYBU,PREX2,SLC9A5,ZKSCAN3,SNCA,CEP68,TMEM121,CDK20,TRIO,PLPPR2,KLC2" Drug 5044_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,NRP2,BAIAP3,LDLRAD4,KALRN,CRLF1,CACNA2D2,VAX2,WHRN,RGS6,HS3ST2,HEYL,AGAP2,SIGLEC8,GNG4,FAM107A,IRAK3,IRF8,C2orf72,SMAD9,MAN2A2,MATK,MMP16,MYT1,PCBP3,NECAB2,SEPT4,SH3BP2,SLA,SLC8A1,SNCA,TNS1,TUBB1,VLDLR,VSNL1" Drug 5319_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "KSR1,LHX2,HOMER3,SMARCAL1,PDE4DIP,DZIP3,ZNF337,TBC1D5,GIT2,DTNA,EGFR,KAT8,FGFR1,FHL1,MPP6,MSL3,HNMT,JAK2,MAP4,NFYA,OXTR,SLC25A23,PLXNB1,RBBP6,TCP11L1,FNDC3A,SPTAN1,ZNF302,ANKRD28,MCF2L,R3HDM1,KCNK12,XRCC4,KCNAB1,MPPE1" Drug 4567_DN Cefixime [79350-37-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NME5,BIN1,CFLAR,SYNJ2,ARHGEF1,QKI,HOMER3,ENTPD4,TBC1D5,KIAA0753,FEM1B,FCF1,ZNF589,PRRC2B,MAP4K5,INPP5B,MPP2,GIT1,CNOT4,PCDH9,PDE1C,PLXNB1,RAD51D,LIMCH1,TMCC1,ZBTB43,POGZ,CEP68,DIP2A,KIAA0930,WIPF1,NDRG4,MPPE1,UBE3B,SMIM8" Drug 7414_DN Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,CDK10,MPDZ,SYNJ2,SYNGR3,EPS15L1,IQCK,PDE4DIP,LYPD1,DTNA,CELF1,MPP6,SRCAP,GLYR1,MUM1,CCSER2,PRKAR1B,PTPN13,TCP11L1,FERMT1,FNDC3A,ABLIM3,PEX26,FNBP1,ELOVL4,CEP68,TACC1,EXOC7,SIN3B,HIRA,LMF1,ZNF45,REEP1,GDPD5,SMIM8" Drug 6599_DN 5194442; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "EPB41L5,CDC14B,ARHGDIG,BMP7,SYNJ2,CACNA1I,CA4,SCARB1,VAX2,IQCK,BAG4,PDE4DIP,ARHGEF4,DGKG,DBN1,MFAP3L,LYPD1,EPB41L2,TDRKH,CNTRL,ELOVL5,NF1,CDK18,LIMCH1,KDM4B,SPART,ARC,PDLIM2,TBCEL,SMG6,TRIM2,SZT2,TMPO,HIRA,ZNF24" Drug 6608_DN Nifurtimox [23256-30-6]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDK10,ARRB2,DNAH17,SYNJ2,CBFA2T2,PLEKHB1,HOMER3,PDE4DIP,SPOCK3,STX2,BAIAP2,ANKFY1,PDLIM5,ZNF276,POLL,GPR37,MAPT,MMP16,LYRM9,GSTCD,FBXW7,SBF1,COA1,SNCA,PDZD2,ZBTB43,LHPP,CEP68,JMJD6,RPGRIP1L,GPR161,CABIN1,UBTF,EMSY,PHTF2" Drug 6482_DN Benserazide hydrochloride [14919-77-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABR,AK2,AMPD2,APC,CDC14B,CDK10,NUMB,C5,KRIT1,SLIT2,CREM,MATR3,DTNA,EZH1,FGFR1,PRELID3A,CSPG5,MSL3,RAB40B,TDRKH,GPER1,BTN2A1,NEK1,PTPRE,TROVE2,CEP68,KLHL7,PLCB1,MTCL1,SATB2,UBE3A,VGF,ZNF74,FZD3,ACTR3B" Drug 1934_UP Dipyridamole [58-32-2]; Up 200; 8uM; PC3; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,NME5,BEGAIN,RASL11B,CRY2,ARHGAP32,ARHGAP24,ZNF337,DAPK1,JAKMIP2,MED12,ZMYND10,SCARA3,AFF2,SRCAP,GFER,CRCP,PADI2,KCNN1,MIA2,MN1,MPP2,SLC25A23,DEF8,PTN,ZDHHC4,DCUN1D2,TCP11L1,SAFB,ZKSCAN3,MMS19,KIAA0930,BHLHB9,TMPO,PLPPR2" Drug 6027_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,C1QTNF3,DOC2A,ARHGDIG,CFLAR,ARHGEF1,FOXN3,PLAA,CREM,CSF1,FAM169A,ZFYVE16,GIT2,DTNA,BAIAP2,ANKFY1,HNMT,INPP5B,LIG4,ADAM22,NF1,MBOAT7,RIPOR1,ZDHHC14,GSTCD,ROBO1,ZNF821,FERMT1,UNC5B,TROVE2,EXOC7,TK2,CDK20,VGF,PHTF2" Drug 5361_UP Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,C1QTNF3,APC,LGR5,ARHGDIG,MARK4,SCAPER,CBR1,QKI,SIPA1L1,PDE4DIP,ARHGEF4,MFAP3L,CDON,FEM1B,NCALD,BAIAP2,FHL1,RASSF8,MAP4,MMP16,MPP2,ZNF862,NEK1,CNNM2,SEC14L1,PPP4R3A,BTBD7,LIMCH1,ZBTB43,EXOC7,CHST8,TRIO,TSC2,GDPD5" Drug 1907_UP Captopril [62571-86-2]; Up 200; 17.2uM; PC3; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,ZBTB10,NUMB,N4BP2L1,CLDN10,FOXN3,IQCK,CDC42BPB,AKAP12,DAPK1,SPOCK2,SPATA2,FBXL5,DTNA,FEM1B,STX2,ACSL4,SEC23B,ALDH1L1,CRCP,GNAO1,PRRC2B,RNFT2,KCTD15,NLE1,ZNF426,TRHDE,MAPK10,NUDT11,FAM192A,VPS13A,OBSL1,UBE3A,EVI5,GDPD5" Drug 6843_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADRA1D,CDC42BPA,PPFIA3,ATP6V0A1,MAGI1,SOCS6,CSF1R,ARHGEF4,FBXL5,DTNA,VPS26C,FGFR1,HSF2,MAPT,MMP16,NCAM2,CNOT4,MINDY2,PRODH,CNNM2,RGS12,RPS6KA2,SBF1,PEX26,SLC9A5,SLC22A4,SNCA,UNC5B,TTBK2,MCF2L,ZNF34,TK2,NPL,GDPD5,MPPE1" Drug 5731_DN Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "MTUS1,ARNTL,NCOA1,CFAP410,ASIC3,SPATA2,SGSM2,SPEG,ETV1,EZH1,CSPG5,SRCAP,GLYR1,GPER1,MAN2A2,SCAMP5,MX1,ZNF862,CNOT4,NPR2,RETREG1,PLCD1,GRAMD1C,RGS3,ZNF671,MCMBP,MAP6D1,KDM4D,COA1,CEP68,CABIN1,VGF,TRIM9,EVI5,AAAS" Drug 1328_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABR,STX16,N4BP2L1,RIPK1,CFLAR,SCAPER,CAPN3,QKI,SLITRK5,KIAA0586,DTNA,FRY,CELSR3,ERCC2,PDLIM5,VSIG4,NF1,NFYA,PDE4B,MAPK3,SAMD9,C1orf109,CEP97,RAD51D,SH3BP2,AMBRA1,NXT2,PJA1,NR2C2,XRCC4,ZNF142,LAMP5,MPPE1,ACTR3B,RNF146" Drug 632_UP "novobiocin sodium, USP; Up 200; 100uM; SKMEL5; HG-U133A" Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,ADD2,SPOP,BEGAIN,CDC42BPA,PKP4,MARK4,WASF1,SPAG9,CNTN1,LETMD1,DCAF8,B3GAT3,FGFR1,ATP2C1,GRM8,RBPJ,IL6R,MATK,MPP2,NFE2L2,NNAT,PALM,PDPK1,FAM102A,PEX26,FAM214B,CAMTA2,BEX4,TP53BP1,SMUG1,TRPM2,UBE3A,JMJD1C,RNF146" Drug 1859_UP Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,KCNAB2,CASK,ARNTL,MARCH3,NCOA1,STX16,CFLAR,SYNJ1,CFAP410,AP4M1,RAB33A,TPP1,FCF1,TUBD1,DISC1,INPP5K,ELOVL5,MAP4,N6AMT1,NF1,CNOT4,PFKFB4,RASA3,TMCC1,IQSEC2,DDN,ARHGEF9,R3HDM1,KAT6B,HIRA,LAT2,EMSY,EVI5,UBE3B" Drug 5531_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,ABHD6,APBB2,MARK4,CFLAR,EPS15L1,ABI3BP,ABCG1,MFAP3L,DPH1,ACOT8,EGFR,DLC1,SEMA4D,GAD1,SPACA9,RNFT2,HSF2,ICA1,KCNF1,MAPT,GIT1,NFYA,PDE4A,NKAIN1,RGS12,GSTCD,PREX2,CDK19,IQCE,CHST8,TK2,BHLHB9,PIK3R5,VAV1" Drug 3170_DN Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "TRMT9B,APOC1,SOCS6,FAM189A2,HOMER3,CRY2,ARHGEF10,SOCS5,FCF1,SUGP2,RGS17,ENO2,ZNF44,GALC,GRB10,LMO2,NFYA,SLC11A2,PMP22,ZCWPW1,RGS12,EMID1,TRAPPC13,KIF13A,KDM4B,THSD1,STX1A,TACC1,MTCL1,IQCE,KIAA0930,TNS2,PCDHA6,WBP2,ZKSCAN5" Drug 5905_UP estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "SEMA6A,SEMA7A,CAMK2B,SLC16A4,SCARB1,EPS15L1,WHRN,CPS1,DTNA,MBNL2,EGR3,SPEG,PIPOX,FHL1,GAD1,TDRKH,JAK2,MGAT3,ADAM22,OPRL1,PGAM2,RETREG1,PILRA,MINDY2,PPP5C,MASP1,RELN,CCDC40,RPS6KA2,CNKSR2,PLCB1,SYNE1,OBSL1,CRTC1,KCNAB1" Drug 2400_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,ADD2,SEMA4G,CACNA1I,MAGI1,CDO1,SLIT2,CREM,ENTPD4,DCAF4,SNPH,OLFM1,INPP5K,GLYR1,ATXN2L,ICA1,KCNJ5,KCNN1,SCAMP5,NELL2,FBXW7,KCNIP1,SH3BP2,PEX26,UNC5B,PEG10,SS18,PHLDB1,DNMBP,PDLIM2,CUX2,NSD1,CRTC1,TPM1,UGT8" Drug 4681_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ACHE,MARK4,ADAM23,ADGRB2,MPDZ,CAMK2B,CBS,USP2,TAOK2,FAM131B,C2CD2L,DPH1,DRP2,ZNF589,ANKFY1,USP21,FYB1,FYN,SIGLEC8,LYVE1,POLL,SPACA9,HLF,MATN3,P2RY13,NOVA2,ENOX1,TCP11L1,SCN2B,PCDHGB6,TMEM121,GPR161,R3HDM1,ZNF24,SEMA3B" Drug 6216_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADCY6,DNAH17,MARK4,BAIAP3,CACNA1A,QKI,PICK1,CSF1R,TBC1D5,DBN1,RUSC2,OPTN,F5,ZNF589,ERAP1,MSL3,RNFT2,ACOT7,HNMT,IGF1,KHK,MMP16,NPTX1,MAPK7,PRPH,SAMD9,NEK11,KCNIP1,ABLIM3,EPN2,ANKRD12,PCDHA5,TK2,SPHK2,MAP3K12" Drug 4603_UP Practolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADGRB1,CACNA1G,RUNX1T1,NRXN3,RGS6,HEPH,DRP2,EDNRB,PLXNC1,ZNF549,AGAP2,FLT1,DOT1L,FYB1,TOX3,IGF1,ITPKA,AFF1,MMP16,MYCN,MYT1,NF1,PDE4D,CCDC102B,KANSL3,ZHX3,DDN,LHPP,ARC,TACR1,TRIM2,TPM1,FLRT2,VIPR2,WIPF1" Drug 5230_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,NME5,SRPX,AMT,SEMA7A,APBB2,APC,APOC1,CACNA1I,CA4,HAP1,CRMP1,FAM169A,FHL1,GFER,POLL,KCNN2,ZNF862,PLCD1,KIF13A,KDM4C,SPTAN1,KIAA1107,R3HDM1,PARD3,TNS1,VLDLR,KCNK12,HPS4,SLC17A7,ITM2C,EPM2A,KAT6A,TIGD6,GAN" Drug 7278_UP Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,CFLAR,PTBP2,RUNX1T1,KRIT1,SCARB1,SRSF11,TAOK2,AKAP7,DBT,IRAK4,C3orf18,VPS13B,FGF13,FGFR1,TRMO,ATP2C1,SYT17,HSF2,IFI16,TJAP1,MIA2,MAPKAP1,MAPK3,FAT4,KDM4D,SLC14A1,TMCC1,ARHGAP26,CEP68,LMF1,EMSY,PLSCR4,PHTF2,RNF146" Drug 6292_UP Metolazone [17560-51-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "C1QTNF3,CDC14B,KIF1A,CAMK2B,CBFA2T2,CHN2,COL9A3,NCOR1,BRINP1,MFAP3L,RUSC2,DTNA,CELSR3,MBNL2,PLXNC1,STX2,SCIN,ITGA7,NELL2,NF1,PDE4B,LRRN3,SAMD9,PTCH1,TMEM231,RFX2,ZNF415,ARHGEF9,EXOC7,FBXW11,CHST8,CABIN1,TRIO,NDRG4,KCNAB1" Drug 6296_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "KIF1A,HAP1,CBFA2T2,QKI,HOMER3,KIAA0753,PLXNC1,DLC1,ZNF589,FGF1,FGFR1,SCARA3,USP19,ZNF276,IRF8,KCNJ5,KCNQ3,KIF5A,ADAM22,PFKFB4,GRAMD1C,WDR25,PTCH1,GSTCD,EMID1,RPS20,ZFP30,PEX26,SLC9A5,SNCA,KDM4B,ZHX3,CHST8,CABIN1,PIK3R5" Drug 443_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ARNTL,ARRB2,ARSE,CACNA1I,BAIAP3,CBFA2T2,ARHGEF2,TAOK2,CLTB,CNTN1,GREB1,ARHGAP32,HS3ST2,RCAN1,DTNA,SRPK3,TBC1D16,RUNDC3A,ADAMTS13,JAK2,NPY,NTRK3,CLDN11,RNASEL,SH3GL3,PKNOX2,ELMO2,CDK5RAP2,ZSWIM8,RGL1,EXOC7,TRPM2,NDRG4,REEP1,HPS4" Drug 833_DN 5255229; Down 200; 13uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CLK4,ARRB1,CLCN3,ARHGEF6,ZNF337,DTNA,PHF20L1,STX2,VPS26C,BAIAP2,TRMO,ERAP1,INPP5K,COPS8,SPIN1,SLC2A6,MATK,NFYA,SETD4,NLE1,PLEC,FA2H,PPP5C,PRKAB2,RGS12,NUBPL,SS18,CEP68,MTCL1,TRIM2,THRA,TMPO,UBE3A,MPPE1,PHTF2" Drug 1407_UP Etodolac [41340-25-4]; Up 200; 14uM; HL60; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "C1QTNF1,MADD,ARRB2,RCBTB2,SRSF11,SMARCAL1,SEC31B,PREPL,VCAN,PPP1R16B,FBXL5,DNM1,DYNC1I1,TOM1,EEF1D,APH1A,EIF5,CD320,FECH,UFM1,ATP2C1,GFER,MSL3,ITGA7,MAP4,NACA,OGG1,PALM,ENPP2,TCP11L1,ASAP3,ZSWIM8,TK2,HIRA,ZNF32" Drug 3236_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,APLP1,EPS15L1,CSF1R,DAPK3,CDON,DTNA,EGFR,EIF4G2,RASGRP2,SEPT9,GRIK5,GRM8,BTN2A1,ATXN2L,KCNQ3,MGAT3,MMP16,MSI1,MSR1,RETREG1,LRP12,SAMD9,RPS6KA2,SGK1,NLGN1,FAM214B,PKNOX2,IQSEC2,TROVE2,PHLDB1,KIAA0930,CRTC1,ZNF34,CABIN1" Drug 2458_DN Cefotiam hydrochloride; Down 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,ADRA1D,ALK,AMPH,CDC42BPA,FAM131A,SEMA4G,MYRF,LDLRAD4,AKAP7,RUBCN,CELSR3,RASGRP2,CDKL3,ZNF276,CRCP,MSL3,MPP2,NF1,NFYA,PDE1C,MAPK10,CNTLN,ZCWPW1,ZDHHC14,ZNF821,SNCA,KDM4B,SPTAN1,IQSEC2,TSPYL2,STX1A,LMF1,EVI5,GDPD5" Drug 5258_DN Clioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,AP2A2,APBA2,APC,ARRB1,PLA2G4C,BMP7,GYG2,CA12,BAG4,EPB41L2,EZH1,EFCAB2,MALT1,GPER1,CACFD1,JAK2,MAPT,NF1,PMP22,KLK6,RET,SBF1,DHX30,PDZRN3,ZC3H13,TROVE2,PLCB1,SYT1,CRTC1,PCDHA6,PCDHA5,CDK20,ZKSCAN5,GDPD5" Drug 5991_DN Phenindione [83-12-5]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,AK2,AMH,PPFIA3,PDE8B,CFLAR,MTMR3,MTMR2,GYG2,CREM,CNTNAP2,GREB1,SUGP2,ANKMY1,EZH1,KAT8,FGFR1,SEMA4D,FAM49B,GAD1,B4GALNT1,TXNL4A,MSL3,KCNMB4,SLC2A6,IL6R,MATK,SETD4,SUPT20H,IQSEC2,TMEM121,TPM1,VIPR2,ZFP37,MPPE1" Drug 3568_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADRA1B,TRMT9B,BIN1,APBA2,KCNAB2,CDK13,CAMK2G,ENTPD2,EPS15L1,TPP1,SNCAIP,SNPH,DUSP9,ERCC2,DLC1,FLT1,FYN,SPACA9,ITPKA,MYCN,NF1,NTRK2,PLCD1,ZCWPW1,RPS6KA2,COA1,SP4,HECW1,LMO3,PHLDB1,TBCEL,DOCK9,SLC44A1,TRO,PARP11" Drug 4233_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "GAS7,CDK13,MARK4,CAMK2B,ARHGAP33,CNTFR,MAML1,SPOCK2,EDN3,EDNRA,ABCA8,GATM,TOX3,SOX21,TJAP1,MMP16,NPTX1,SERPINI1,MAPK10,CNNM2,PTPRH,GAL3ST4,ZMAT4,RGS3,RTN1,CNKSR2,SLC12A4,DDN,ASTN2,MCF2L,DICER1,TNS1,NPL,TUBB1,DPF3" Drug 7430_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,KSR1,ST3GAL5,SCAPER,CFAP410,PLEKHB1,NECTIN3,TBC1D5,ARMCX2,JAKMIP2,C2CD2L,NR1D2,VPS13B,COQ7,VPS26C,FHL1,INPP5K,ICA1,KCNF1,KCNN1,ADAM22,RETREG1,ING3,FSD1,PTCH1,RGS12,GSTCD,SEC14L1,FAM214B,SNCA,SS18,LMF1,NDRG4,MAP3K12,UBE3B" Drug 1178_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APBB2,APOC1,ARNTL,NCOA1,CRY2,CSNK1E,PDE4DIP,CNTNAP2,KIAA0753,EIF4G2,EPB41L2,RASGRP2,ANKMY1,ANKFY1,INPP5K,PCDH17,IL6R,LSS,MEF2C,MX1,NINJ2,SLC11A2,NTRK2,P2RX7,STRN3,NECAB2,POLG,MINDY2,PTPRN2,KLHL11,SLC11A1,ZBTB43,RGL1,EXOC7,PHTF2" Drug 7302_DN Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RGS20,EIF4G3,ARHGEF1,FOXN3,CHN2,RAB28,ARMC8,ENTPD4,DBT,B3GAT3,C2CD2L,TAOK3,TRAF3IP2,INPP5K,GLI2,CNTRL,HNMT,FAM69A,MAPT,MPP2,SLC11A2,SERPINI1,RAD51D,DCUN1D2,KIRREL1,FBXW7,AP1AR,ZKSCAN3,ELOVL4,CEP68,NSD1,XRCC4,SH3GLB2,EVI5,SMIM8" Drug 915_UP topiramate; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APAF1,APBB2,APC,PPFIA3,GYG2,SRSF11,SH2B1,PPP6R2,GIT2,DBT,AASS,RGS17,CDKL3,RACK1,GNG4,PRUNE2,CNTRL,RNFT2,INPP5B,KCNH2,MAP4,NCAM2,FA2H,MINDY2,PPP5C,RGS12,RNASEL,TRAPPC13,EPN2,POGZ,THSD1,TTBK2,JMJD6,VLDLR,ITM2C" Drug 6459_DN S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,SEMA6A,AMH,CDC42BPA,FAM131A,CDK10,PLA2G4C,LDLRAD4,B4GALT6,RAB28,ENTPD4,GREB1,EGFR,OGA,DISC1,HNMT,KCNH2,KHK,PRODH,TMEM104,FAM184A,RGS3,EPN2,FAM214B,LIMCH1,IQSEC2,LHPP,POGZ,ARC,TMEM121,SLC44A1,XRCC4,MAP3K12,EVI5,MPPE1" Drug 1950_UP Josamycin [16846-24-5]; Up 200; 4.8uM; PC3; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BIN1,FUBP1,GYG2,CAMK2B,CLDN10,CCNT1,CRY2,CTH,RASSF2,E2F5,SPEG,ACSL4,FGFR1,PDLIM5,TRAF3IP2,DENND2A,B4GALNT1,TDRKH,INPP5B,NELL2,NTRK3,PLCD1,C19orf57,RGS4,SH3BP2,SMARCD3,TSPYL2,NXT2,WSCD1,NSD1,UCHL1,MAP3K12,EVI5,SLC17A7,DPF3" Drug 1969_DN Dibucaine [85-79-0]; Down 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "N4BP2L1,MTMR2,CD38,FOXN3,EPS15L1,QKI,SMARCAL1,NCOR1,TM9SF4,SGSM2,RCAN1,DTNA,DCTN4,SEC23B,STAU2,CRCP,INPP5B,ITGAM,MAP4,MBNL1,GIT1,NACA,PIK3R1,AP1AR,ZKSCAN3,SMARCC2,INTS9,CLASP2,STAU1,DIP2A,ZEB1,CHST5,ELP5,TSN,VPS35L" Drug 6346_UP Sulfasalazine [599-79-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,NDRG2,ADORA1,AMT,SCARB1,SEPT7,PICK1,CNTFR,AKAP7,HINFP,CSNK1E,DZIP3,DMPK,EDIL3,EZH1,CGREF1,DISC1,NEU3,GFER,GLYR1,PRRC2B,LPAR4,SCIN,ITPKA,PLCD1,FSD1,CNTLN,C1orf54,TCP11L1,STUM,DZIP1,IFT122,LHPP,CEP68,R3HDM1" Drug 161_UP (+/-)-verapamil hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "SEMA6A,ALCAM,SEMA7A,KCNAB2,PRX,AZGP1,SCAPER,CACNA1I,RAB29,AP4M1,FOXN3,EPS15L1,CNTFR,SH2B1,CRMP1,NCOR1,SUGP2,EGR3,ETV1,SRCAP,CRCP,BTN2A1,CLASRP,ATXN2L,CNOT4,NTRK3,OXTR,CNNM2,PTN,CRTAC1,ATP10B,POGZ,PHLDB1,VIPR2,ST7" Drug 4230_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDK10,SEMA4G,CFLAR,SCARB1,HOMER3,ENTPD4,VCAN,CNTNAP2,ZNF337,DBT,DMPK,DTNA,ERCC2,ST3GAL6,ANKFY1,RUNDC3A,ATXN2L,ITPKA,KCNN1,LIG4,MATN3,AFF1,OCRL,GRAMD1C,PTN,FBXW7,FRMPD1,ANKRD6,LIMCH1,ASTN2,TK2,BEX4,CABIN1,ZNF74,ACTR3B" Drug 7344_DN Oxamniquine [21738-42-1]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG3,PPFIA3,CDK13,MARK4,NUMB,CFLAR,SCAPER,MTMR2,CA12,ARHGEF1,PDE4DIP,DBN1,TMCC2,CELSR3,BAIAP2,FHL1,FAM49B,MSL3,LIG4,LMO2,MAP4,MPP2,SLC11A2,SETD4,PRKAR1B,SAFB,COA1,ZBTB43,THSD1,TRIM2,SZT2,CABIN1,LMF1,UBE3B,ACTR3B" Drug 6231_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AP2A2,SRPX,TRMT9B,AMT,APC,SHROOM2,TPP1,FAM189A2,MAP4K4,PPP6R2,MFAP3L,TMCC2,E2F5,ING4,F5,ACSL4,ZNF589,MALT1,TDRKH,DHX35,IL6R,PRODH,SAMD9,ZSCAN32,NEK11,SH3BP2,EPN2,ZBTB43,EXOC7,PCDHGA10,SLC44A1,CABIN1,VGF,VIPR2,MPPE1" Drug 2013_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "GAS7,NCOA1,RCBTB2,SRSF11,TAOK2,ZNF804A,PHF20L1,CD320,EZH1,FKTN,ATP2C1,FYN,TRAF3IP2,SEPT9,GRIK5,MAN2A2,MITF,NFYA,RDX,SH3BP2,CCDC88A,MAPKBP1,DOP1A,HECW1,MCF2L,EXOC7,SIRT1,TK2,TP53BP1,WBP2,CLDND1,ZNF32,ZNF142,SMIM8,DPF3" Drug 252_DN celecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,OGT,GAS7,SLC4A4,HIP1R,CD86,LHX2,SMARCAL1,DRP2,DTNB,EIF4G2,DISC1,BTN2A1,PTPRT,C2orf72,IGF1,KCNJ5,LAMP2,STMN1,LIMS1,NF1,NPR2,STRN3,PPP2R2B,KLHDC8A,ROBO1,SATB1,ATXN2,FNDC3A,SPART,SSTR2,PRRC2C,ANKRD12,UGT8,ZNF23" Drug 7488_DN ST021200; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,C1QTNF3,GAS7,SLC4A4,CAMK2G,CBFA2T2,SLIT2,HDAC4,GIT2,JAKMIP2,DTNA,ING4,STX2,PIPOX,TRAF3IP2,SYNPO,KIT,AFF1,ZNF862,PRKAR1B,MAPK7,PRPH,RAD51D,ZNF821,SMARCD3,RCOR3,KDM4B,KDM4C,VPS13A,PLCB1,WSCD1,RPGRIP1L,SLC44A1,UCHL1,REEP1" Drug 6336_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ACTN1,APLP1,CNOT8,ARHGAP32,C2CD2L,SGSM2,FER,FGFR1,BAIAP2,TRAF3IP2,TMEM8B,DISC1,CRCP,GPER1,GUCY1A1,MAP4K5,N6AMT1,SLC11A2,CLDN11,NLE1,MAPK3,ELOVL2,PTPRN2,TRAPPC13,FUZ,SLC6A8,ZBTB43,ARHGEF9,KIAA0930,PLPPR2,XRCC4,TRIM9,FTSJ1,TFIP11,ST7" Drug 5056_DN L(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,BRAP,ALDH7A1,MYRF,SLITRK5,ARHGAP24,EXOG,DPH1,HIPK3,MBNL2,ACSL4,ZNF589,BAIAP2,PDLIM5,CGREF1,USP19,CNTRL,RASSF8,MEF2C,SLC11A2,RGS4,TCP11L1,MAPK12,COA1,TMCC1,SP2,NXT2,TTBK2,GPR161,TK2,SSBP2,OSBP2,SPHK2,EVI5,UBE3B" Drug 1838_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,CDC42BPA,ATP1A3,SYNJ1,CBFA2T2,ZMYM4,TPP1,IQCK,DAPK3,PLXNC1,PIPOX,FLNC,AHDC1,CACFD1,KCNN1,MAP4,NEFH,CNOT4,PIK3R1,PTN,RIPOR1,TCP11L1,PLPPR3,FUZ,SLC6A8,ARHGEF40,SLC12A2,CDK19,RBM26,TROVE2,ADGRL3,PARD3,TRPS1,CLIP2,SPHK2" Drug 3626_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ALCAM,BIN1,GAS7,PPP4R4,RASL11B,ATP6V0A1,SYNJ2,BAIAP3,CLGN,TAOK2,CNTN1,GIT2,DBN1,ZNF589,ZNF276,POLL,GSN,IL6ST,KPNA5,MMP17,GIT1,LYRM9,NF1,PLCD1,TMEM104,ZSCAN2,ZFHX4,RXRA,FAM214B,SNCA,DOK5,THSD1,RGL1,PCDHA5,THRA" Drug 3088_DN Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,APOC1,LDLRAD4,CAMK2B,SCARB1,B4GALT6,CLOCK,CREM,ARHGEF10,DBT,HIPK3,OPTN,EIF4G2,TNK2,COQ7,CD320,KAT8,EFCAB2,ALDH1L1,LILRB4,LILRA2,IL6ST,PLCB2,PLTP,MAPK7,PTCH1,FBXW7,ZNF671,ARHGEF40,PLCB1,EXOC7,DNMBP,TRPS1,FLRT2,TIGD6" Drug 461_UP LY294002; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AMT,OGT,ARNTL,RUNX1T1,SRSF11,LY86,CRMP1,DAPK1,MBNL2,VPS13B,EXTL2,EZH1,NSG1,INPP5K,PCDH17,ZNF638,GNAO1,IRF8,AFF1,MN1,LYRM9,CCSER2,MINDY2,RET,SEMA6D,SBF1,PKNOX2,SNAP25,ZC3H13,CDK19,ATP10B,DMXL2,ZNF24,SLC17A7,PLSCR4" Drug 1411_UP Thalidomide [50-35-1]; Up 200; 15.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APOC1,ST3GAL5,ARHGEF1,ARHGAP33,PPP1R16B,ARHGAP32,ZNF337,SGSM2,MED12,DRP2,DTNA,ING4,SRPK3,EPB41L2,DLC1,FCGRT,PRKAG2,ERAP1,DISC1,RUNDC3A,LILRA2,MAN1B1,MAN2A2,NACA,PDE1C,CCSER2,MBOAT7,CNNM2,PTPRN2,EPN2,KBTBD4,ELMO2,PLCB1,SZT2,VIPR2" Drug 5262_DN Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,AP2A2,ALK,APC,SEMA4G,ALDH7A1,SYNJ2,CFAP410,CA4,HOMER3,ARHGEF4,RASSF2,MFAP3L,PARD6A,CNNM1,MRNIP,PIPOX,FGFR1,CACFD1,KIF5A,NPTX1,GPR85,PLEC,MBOAT7,ZFHX4,NEK11,FBXO11,EPN2,SLC9A5,CXXC4,COA1,PDLIM2,WSCD1,TRIM2,SIK3" Drug 1020_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APC,BCAS1,CDK10,CFLAR,SCARB1,USP6NL,DCAF8,DBT,ING4,COQ7,CDKL3,EZH1,KAT8,ZNF589,FGFR1,TRMO,OGA,TXNL4A,HNMT,HSF2,MBD1,NFYA,PLXNB1,PRKAR1B,GTDC1,NEK11,EPN2,KBTBD4,MCF2L,TIAM1,KAT6B,LMF1,EMSY,PRDM10,SEMA3B" Drug 7313_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AP2A2,NME5,APOC1,CDK10,KYAT1,RCBTB2,CHN2,VCAN,PARD6A,CDON,SPEG,VPS26C,RASSF8,MAN1B1,MIA2,MN1,MX1,SERPINI1,SH3TC2,SUGCT,FBXW7,SAFB,MAPK12,ASAP3,FUZ,EPN2,FAM214B,ZNF415,KDM4C,PHLDB1,ZNF34,R3HDM1,CABIN1,RUNDC3B,EVI5" Drug 6460_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,C1QTNF1,ALCAM,KSR1,SCAPER,SGCE,CBFA2T2,CSF1,RIMS2,F5,AGAP2,KHDRBS3,ERAP1,SRCAP,MSTN,GPR75,IL6R,KCNJ5,MARK1,MBD1,ADAM22,NF1,NKAIN1,RAD51D,ENOX1,ZNF493,RGS12,EMID1,KANSL3,SLC11A1,TSNAXIP1,PLCB1,TRIM2,KCNAB1,JPH3" Drug 7554_DN ST021200; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AK2,SYNJ2,BAIAP3,CBFA2T2,RAB33A,VAX2,HOMER3,CRY2,NCOR2,DTNA,ZNF589,FGF12,AHDC1,GNG4,MAP4K5,TJAP1,KCNN1,MIA2,AFDN,MSI1,ZNF862,LRP12,PRKAR1B,TCP11L1,SIRT2,BTBD7,ZKSCAN3,SNCA,SP4,ANKRD12,TPM1,HIRA,VIPR2,ZNF74,EVI5" Drug 7016_DN Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDC42BPA,EP400,APC,BCAS1,PPFIA3,ARRB2,MPDZ,ARHGEF7,MTMR2,C5,SPAG9,LHX2,RAB28,STOML1,SOCS5,DCAF8,KIAA0586,DCTN1,DPH1,IRAK4,VPS26C,SRCAP,ZNF276,COPS8,DHX35,MITF,SMIM7,STRN3,ZCWPW1,TRAPPC13,ZFP30,ANKRD6,CDK19,ARHGEF9,CABIN1" Drug 3610_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,NDRG2,ALCAM,GAS7,FAM131A,PPP4R4,ADAM15,CBFA2T2,SLIT2,RCHY1,NCOR1,DAPK3,HIPK3,EPB41L2,ZNF589,FGF13,ERAP1,TXNL4A,GLYR1,SPACA9,GSN,MAP4K5,IL6ST,KPNA5,NLE1,PLXNB1,RIC8B,FAM214B,IQSEC2,STX1A,KIAA1107,RPGRIP1L,MAP3K12,PCBP4,PHTF2" Drug 3417_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABR,AK2,LTBP4,AMPH,CDC42BPA,ALDH7A1,CFLAR,GYG2,CAMK2G,ZMYM4,ASIC3,TAOK2,AKAP7,DAPK3,ZNF804A,CDON,STX2,FAM49B,SIGLEC8,SEPT9,GNAO1,LSS,MIA2,ADAM22,ZDHHC14,GSTCD,EMID1,BTBD7,SPART,SS18,IQCE,PCDHA5,CABIN1,SPHK2,KCNAB1" Drug 3356_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,BRAP,SEMA6A,BIN1,ATP6V0A1,CAMK2B,HIP1R,RUNX1T1,CLGN,CHN2,CNR1,MFAP3L,VPS13B,ERCC2,DCTN2,TRAF3IP2,TDRKH,MAPT,ADAM22,PLXNB1,C19orf57,LRRN3,ZMAT4,TRIM68,EMID1,CXXC4,COA1,DOK5,ATP10B,DMXL2,SZT2,HIF3A,DNAH7,TRPM2,DNALI1" Drug 1073_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASPHD1,NCOA1,STX16,ATP6V0A1,FUBP1,C5,HIP1R,FOXN3,LHX2,NCOR1,LRIG1,ARHGAP32,GIT2,OPTN,ERBB2,GFER,GHR,HTATSF1,CLASRP,MAN1B1,MMP16,SLC11A2,OGG1,KCTD15,ROBO1,ATXN7,PDZRN3,SYT1,PARD3,KAT6B,SSBP2,UBE3A,UBTF,MTCH1,IFT88" Drug 2746_DN Tomatidine [77-59-8]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDC42BPA,APOC1,BCL7A,SPAG9,MAGI1,CNOT8,CREM,CSNK1E,LYPD1,PARD6A,DTNA,KAT8,ZNF589,FGFR1,BAIAP2,SEMA4D,AHDC1,MAN2A2,MBD1,MIA2,KITLG,NEK1,NPR2,PTK2,C1orf109,RIC8B,FBXO11,ZKSCAN3,CDK19,CLASP1,DOCK9,PCDHA6,HIRA,ZNF24,MAP3K12" Drug 3894_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,SEMA6A,AMPH,APAF1,CDC14B,PDE8B,ATP2B2,HAP1,RHBDL1,CDH2,LHX2,AKAP7,AATK,ARHGEF10,IPCEF1,TMCC2,C3orf18,DLC1,ADAMTS13,IGF1,KIT,LAMA2,MGAT3,MMP16,MYO7A,NPTX2,PDE4A,LRP12,NECAB2,MINDY2,KCNIP1,CLIP1,EPN2,KDM4B,DICER1" Drug 1743_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,ARNTL,ENTPD6,CLOCK,CRYM,TM9SF4,GIT2,KIAA0753,DPH1,EGR3,ING4,TRAF3IP2,ALDH1L1,SRCAP,RUNDC3A,ACOT7,JAK2,MYT1,OCRL,NLE1,PLCB2,PLCD1,RNASEL,SAFB,ATXN7,ZNF821,FNDC3A,KBTBD4,NXT2,PLCB1,PHF24,PARD3,XRCC4,ZNF24,GDPD5" Drug 6616_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ALK,AMPH,SEMA7A,EPB41L5,GAS7,ATP6V0A1,SYNJ1,MTMR3,CNTN1,AKAP5,ENTPD4,CSF1,ARHGEF4,EDNRA,HIPK3,ING4,FGF1,DCTN2,ALDH1L1,CYP46A1,PRUNE2,PADI2,C2orf72,PIK3R1,PRPH,VPS13C,PTN,PTPRD,CARF,KCNIP1,SNCA,TMCC1,THRA,EPM2A,DPF3" Drug 5526_DN Prednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "PPFIA3,BMP7,MTMR2,FAM169A,FEM1B,CELSR3,EGFR,MRNIP,FECH,FHL1,BTN2A1,SLC2A6,PADI2,ITPKB,MAPT,MIA2,OGG1,PCDH9,PRKAR1B,RNASEL,NUBPL,BTBD7,CDK5RAP2,RCOR3,TROVE2,TACC1,EXOC7,TRIM2,NSD1,CHST8,VAV1,XRCC4,TFIP11,EVI5,RNF170" Drug 7275_DN Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,PKP4,PPFIA3,CLTB,CSNK1E,KIAA0753,TMCC2,SUGP2,ING4,STX2,FHL1,ATP2C1,DISC1,TXNL4A,MEIS1,MYO6,ZNF862,NFIX,NFYA,PDE1C,PIK3R1,POLG,PRKAB2,BCAS3,ZDHHC14,PEX26,SMARCC2,CDK5RAP2,SP2,EXOC7,WSCD1,HIRA,PLSCR4,UBE3B,SMIM8" Drug 3276_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APBA2,CDC14B,PLA2G4C,ARHGAP33,WHRN,DZIP3,KIAA0586,CNNM1,ENO2,VPS13B,FHL1,GLYR1,STON1,GPER1,ICA1,KCNH2,KCNN2,LMO2,MYCN,ZNF862,NPR2,CEP41,MAPK7,PRPH,C1orf54,TRIM68,SUPT20H,ASAP3,LIMCH1,SMG6,THRA,CDK20,BCL2L13,VLDLR,EMSY" Drug 3044_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APBB2,NCOA1,AZGP1,CFAP410,HIP1R,SLC16A4,CLGN,PLAA,TPP1,ZNF337,TM9SF4,HIPK3,MTSS1L,DLC1,FHL1,EFCAB2,GCNT2,LILRA2,GSN,TJAP1,PDE4D,LRRN3,ZDHHC14,ZNF821,SH3BGR,PPM1E,CCDC88A,TMCC1,CEP68,ADGRL3,KIAA1107,TNS2,TRPS1,SSBP2,PHTF2" Drug 1810_DN Sulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "PPFIA3,SHROOM2,SEMA4G,ST3GAL5,CA12,LHX2,CSF1,SCML2,FGFR1,SCARA3,SYT17,GPER1,KIF2A,KIFC3,PDCD2,SLC25A23,PRKACB,SAMD9,ZSCAN32,PTPN13,ROGDI,CCDC25,MCMBP,SUPT20H,KIF16B,AMBRA1,LIMS2,IFT122,POGZ,STX1A,NDRG4,MAP3K12,VPS35L,PLSCR4,ACTR3B" Drug 1268_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,BIN1,CDC42BPA,APBB2,PPFIA3,ADAM23,ST3GAL5,SYNJ2,CFAP410,CD86,SEPT7,DZIP3,SPOCK3,EFCAB2,CINP,MAP4,MEF2C,GIT1,NEK1,RETREG1,PLCB2,PPP3CC,TMEM104,ZNF493,ARFGAP1,MAPKBP1,TMCC1,FNBP1,PLCB1,EXOC7,UBTF,PLPPR2,SPHK2,EVI5,HPS4" Drug 3145_DN Isometheptene mucate; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,MTUS1,AGT,APOC1,MARK4,CNTN1,IQCK,CREM,ABCG1,DGKG,SPOCK2,ERCC2,ETV1,DLC1,AGAP2,ZNF44,IL6ST,KCNJ5,CNOT4,OGG1,PFKFB4,PLCD1,ZFHX4,ST6GAL1,TSNAXIP1,SP4,ARHGAP26,IQSEC2,ST5,NSFL1C,SYN2,PCDHGA10,SYNE1,THRA,MAP3K12" Drug 5250_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,APBA2,GAS7,BCAS1,CDK10,SYNJ2,GYG2,SH2B1,RASSF2,EXOG,SLC12A6,ING4,FGFR1,FHL1,NOP56,PADI2,ELOVL5,AGFG1,ICA1,KCNF1,KCNH2,MPP2,LRP12,PTPRE,ZDHHC14,ZFHX4,TCP11L1,RPS6KA2,SEC14L1,RBM34,TBCEL,CDK20,KLC2,SMIM8,RNF146" Drug 4664_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,ASPHD1,BBOX1,MTMR7,STOML1,VAX2,HOMER3,ABCG1,C2CD2L,DRP2,HIPK3,EZH1,FYB1,SIGLEC8,GPR75,GNAL,GRM8,KCNN1,LSS,GIT1,MYO7A,P2RX7,NLE1,ZNF426,PTH1R,RAD51D,ARHGAP26,ZBTB43,TROVE2,KIAA1107,RPGRIP1L,UGT8,VIPR2,ZFP37,JPH3" Drug 1506_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "EPB41L5,GAS7,ARRB1,ATP6V0A1,CFLAR,CAMK2G,SULT4A1,ABCG1,PDE4DIP,ARHGEF4,GPRASP1,DTNA,DENND4A,FAM49B,FYN,RAB30,PADI2,INPP5B,NLE1,MBOAT7,PRKAR1B,GTDC1,RGS12,TCP11L1,SBF1,ZNF821,SUPT20H,AMBRA1,ANKRD6,PPP4R3A,BTBD7,MAPKBP1,CRTC1,CABIN1,ST7" Drug 6408_DN valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,ADRA1D,APBB2,SYNJ1,WASF1,MYRF,CAMK2B,CBFA2T2,CRLF1,SOCS6,STOML1,CSNK1E,PDE4DIP,CNTNAP2,DZIP3,CNNM1,DENND2A,GLYR1,INPP5B,NF1,PFKFB4,RGS12,SLC12A4,ZNF415,SPTB,MCF2L,KIAA0930,TRIM2,CHST8,GPR161,PIK3R5,CDK20,NT5M,SEMA3B,RNF146" Drug 3477_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "GAS7,APOC1,PPP4R4,RASL11B,ATP6V0A1,SYNJ1,GYG2,HAP1,CAMK2B,NECTIN3,SH2B1,ARHGEF4,C3orf18,TDRKH,INPP5B,KPNA5,MAP4,KITLG,ZNF862,PCDH9,PLEC,APTX,C1orf54,ZDHHC14,GTDC1,RGS12,RPS6KA2,PREX2,BTBD7,SPTAN1,KIAA0930,PCDHA5,ZNF34,EMSY,EPM2A" Drug 638_DN genistein; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NCOA1,ADAM23,SGCE,CD86,AP4M1,ARHGAP32,GAPVD1,GIT2,DRP2,SRPK3,BAIAP2,ANKFY1,MALT1,RUNDC3A,GLYR1,PDPK1,PLEC,PLXNB1,MAPK10,SUSD4,KCTD17,PPP4R3A,KBTBD4,ELMO2,KDM4B,FNBP1,GLT8D1,DBNDD2,TACC1,ANKRD12,PARD3,SSBP2,VIPR2,REEP1,UPF3A" Drug 3018_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADGRF5,BIN1,CDC42BPA,CACNA1I,MTMR7,DLGAP1,SLC4A8,RGS6,SUSD5,DZIP3,INTS1,EXOG,OPTN,PRELID3A,SIGLEC8,INPP5K,ADAM28,GPR37,HNMT,NPY,CLDN11,PCDH9,FSD1,BCAS3,ZSCAN32,SLC11A1,ZNF423,CDK19,ARHGEF9,SYT1,TACR1,AP4E1,RUNDC3B,FLRT2,ZNF225" Drug 4794_DN Diflunisal [22494-42-4]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDC42BPA,CDC14B,CFLAR,GYG2,CFAP410,HAP1,LRRFIP1,PPP6R2,GPRASP1,MFAP3L,RCAN1,ANKMY1,FECH,FGFR1,SPACA9,ELOVL5,MAP2,MID1,AFDN,SLC11A2,PPARA,RPS6KA2,SH3BP2,ANKRD6,KIF13A,IQSEC2,PCDHGA10,DOCK9,NSD1,THRA,PARD3,VLDLR,LMF1,XRCC4,KCNAB1" Drug 4441_DN chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AP2A2,C1QTNF1,C1QTNF3,AMT,ADAM23,ADGRB2,CFAP410,NRXN3,RAB26,AKAP7,COL9A3,CSF1R,RUSC2,CELSR3,PLXNC1,ING4,FGFR1,POMT1,PRELID3A,ICA1,SHISAL1,KITLG,PFKFB4,PLCB2,SLC25A23,TMEM231,FUZ,SNCA,SPTAN1,LHPP,SAMSN1,IQCE,ZEB1,GPR161,DPF3" Drug 3675_DN Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,AMPD3,APC,APOC1,ARNTL,NCOA1,RASL11B,HAP1,CBFA2T2,ARHGEF6,IQCK,VCAN,ZNF337,MAML1,DAPK3,RCAN1,SCML2,TRMO,OGA,MBD1,OCRL,CLDN11,SERPINI1,RETREG1,RAD51D,NEK11,DZIP1,SS18,ARHGEF9,ARC,XRCC4,ZNF45,NDRG4,MPPE1,GAN" Drug 4812_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APAF1,APBA2,APC,MARK4,HOMER3,PICK1,ENTPD4,NCOR2,ARMCX2,RCAN1,DTNA,GAD1,HPGDS,GNAL,GRB10,TJAP1,NF1,PCBP3,PCDH9,MINDY2,PRKAR1B,CCDC25,FBXW7,TCP11L1,EMID1,KANSL3,KIF13A,IZUMO4,TROVE2,PHLDB1,TNS1,CDK20,CHST5,TRIO,SLC30A3" Drug 7244_DN Asiaticoside [16830-15-2]; Down 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,BIN1,EP400,APBB2,MADD,KYAT1,CSNK1E,RCAN1,SUGP2,ING4,MFSD10,COQ7,ANKFY1,POMT1,SRCAP,CCSER2,KCTD15,PLCD1,SMIM7,SAMD9,SNRK,PTN,MAP6D1,SEC14L1,SUPT20H,DOP1A,PDZD2,ZBTB43,SS18,TCF4,TNS2,TRPM2,LMF1,ZBTB14,ACTR3B" Drug 7257_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BIN1,APC,PICK1,CSF1,GIT2,RUSC2,KLHL3,FEM1B,STX2,BAIAP2,COPS8,LIG4,MBD1,NF1,NOVA2,PALM,ZCWPW1,RGS4,AMBRA1,PPP4R3A,MYH15,ARHGAP26,SPTAN1,SPTB,SPART,CEP68,SYT1,TRIM2,ZNF34,R3HDM1,XRCC4,TFIP11,EMSY,KAT6A,RNF170" Drug 2126_DN Cloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADRA1D,APC,MARK4,SYNJ2,RAB29,CACNA2D2,HOMER3,IQCK,CSF1,PDE4DIP,DZIP3,ZFYVE16,TBC1D5,SPOCK3,CDON,SLC12A6,CNNM1,EGFR,ING4,TRAF3IP2,DISC1,GPER1,SLC2A6,SHISAL1,PDCD2,MCMBP,SH3BGR,CDK19,SS18,KIAA1107,ZEB1,TRIM2,TMPO,CABIN1,ACTR3B" Drug 1533_DN Loperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG3,AP2A2,AMPD2,PPFIA3,ARRB1,SOCS6,CLCN3,CLTB,CREM,CSNK1E,PARD6A,CNNM1,FER,MALT1,GLYR1,MSL3,GPR37,CACFD1,ITPKB,KCNH2,MAP4,MAPT,MMP16,MPP2,PLEC,TCP11L1,ZNF821,ANKRD6,CLSTN2,ASTN2,TNS2,ZMAT3,TPM1,LMF1,ST7" Drug 2822_DN Benzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AMPD3,GAS7,MARK4,BMP7,RUNX1T1,CBFA2T2,PICK1,CSF1,SIPA1L1,SPOCK2,CDON,EDNRB,EIF4G2,NCALD,DLC1,FHL1,ALDH1L1,KCNN2,KHK,MMP16,MX1,ZNF862,NEK1,RETREG1,WDR25,ZDHHC14,NEK11,LIMCH1,MAPKBP1,ARHGAP26,PHLDB1,SYNE1,VIPR2,SLC30A3,KCNAB1" Drug 6812_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ASIC1,ADORA1,BIN1,BAIAP3,CAMK2B,CDH2,CLGN,CNOT8,RAB33A,PDE4DIP,SEC14L5,DTNA,DUSP9,EDN3,NCALD,ACSL4,HPCAL4,FYN,GAD1,CRCP,RAB30,HNMT,IL6R,AFDN,CLDN11,PDE1C,ZSCAN2,EMID1,CAMTA2,SMG6,TK2,TRO,LAT2,SPHK2,SLC17A7" Drug 7243_DN Urosiol [128-13-2]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BRAP,APLP1,RAB28,IQCK,ABI3BP,PPP6R2,KIAA0753,PARD6A,SGSM2,SLC12A6,EIF5,SPEG,FECH,ANKFY1,TRAF3IP2,RNFT2,MITF,SETD4,SMIM7,POLG,CSRNP3,SMARCC2,PDZD2,NMNAT2,UHRF1BP1L,ZBTB43,DIP2A,DNMBP,TMEM121,METTL3,TRPM2,XRCC4,FIP1L1,TIGD6,AAAS" Drug 5645_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "BIN1,PRX,SLC4A4,KSR1,CACNA1I,CHN2,WHRN,CPS1,SPOCK2,ECM2,TENM1,EZH1,FUT9,SIGLEC8,KIF5A,MYCN,NOVA2,NTRK3,ZSCAN2,C1orf54,KLHDC8A,PNMA8A,EMID1,ZFP2,SLC2A5,LIMS2,SLC9A5,SLC11A1,TSNAXIP1,PEG10,EXOC7,ADGRL3,WSCD1,CHST5,WIPF1" Drug 3736_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADRA1D,NME5,ALK,APAF1,GAS7,PPP4R4,ALDH7A1,NRP2,SYNJ1,ARHGEF2,TAOK2,NCOR2,CNTNAP2,MFAP3L,EXOG,ECM2,EDNRA,SEMA3D,MBNL2,EPHB1,GPD1,GRM2,MAP4K5,KCNH2,LIG4,ADAM22,CNOT4,CLDN11,KHDRBS2,RPS20,ZNF334,RBM34,ATP10B,FLRT2,KCNAB1" Drug 6630_DN Fursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "KIF1A,CAMK2G,CBFA2T2,SCARB1,LARGE1,SOCS6,PLEKHB1,B4GALT6,PICK1,IQCK,VCAN,SLITRK5,DZIP3,FEM1B,EGFR,MBNL2,COQ7,ZNF549,FYN,GAD1,INPP5K,PPARA,WDR25,PID1,FBXW7,RPS6KA2,AMBRA1,DDN,ELOVL4,CRTC1,TMEM121,TK2,ZBTB14,MAP3K12,SEMA3B" Drug 1272_UP Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG3,MTUS1,APAF1,APBB2,NCOA1,CFAP410,CAPN3,CLGN,SIPA1L1,ARHGAP32,ZFYVE16,RCAN1,VPS26C,CELF1,GNAO1,GPD2,TJAP1,LSS,SLC11A2,SLC25A23,PPP3CC,PTPRO,PPM1E,DZIP1,ELMO2,ZKSCAN3,TMCC1,FNBP1,TROVE2,LARP4,DNMBP,ZEB1,CHST8,FLRT2,SENP7" Drug 6865_DN SC-560; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NME5,KIAA1324,APC,CDK10,SLC4A4,RGS11,SCAPER,CFAP410,ARHGAP33,NRXN3,CNTFR,AKAP7,AATK,ACOT8,CELSR3,MBNL2,EIF5,ING4,MRNIP,ERCC2,DCTN2,CGREF1,ERAP1,NPR2,PTPRE,CCDC40,ZNF671,CSRNP3,SH3BGR,SPTAN1,CEP68,MCF2L,THRA,TIMP4,CDK20" Drug 1571_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AK2,AMT,CFLAR,CA12,HIP1R,PLAA,RCAN1,DCTN4,VPS26C,UFM1,FAM49B,CELF1,OGA,GSN,NCKAP1L,PDPK1,ZNF426,LRP12,TTC13,CLIP1,ATXN7,SLC2A5,ZNF430,ARHGEF40,SLC11A1,SNAP25,POGZ,DIP2A,KANK1,NSFL1C,TBL1X,NSD1,TMPO,EIF4ENIF1,PHTF2" Drug 1978_DN Prednisone [53-03-2]; Down 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,MARK4,N4BP2L1,ATP6V0A1,CD38,CLOCK,ARHGAP32,GIT2,DBT,SGSM2,ACOT8,DTNA,ST3GAL6,CAMKK2,CLASRP,GSTM5,HNMT,AGFG1,INPP5B,MAP4,MITF,NEFH,NF1,MAPK3,MAPK10,C12orf49,PLPPR3,SBF1,SHMT2,ELMO2,MAPKBP1,KANK1,SZT2,KAT6B,CHST5" Drug 1529_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,MARK4,ATP1A3,CFLAR,CFAP410,RAB33A,PLAA,QKI,SNCAIP,CNTNAP2,SPOCK2,DBT,MFAP3L,CDON,STX2,PDLIM5,SRCAP,COPS8,KIFC3,TM6SF1,MIA2,AFDN,PCBP3,PDE1C,PFKFB2,VPS13C,KCTD17,KCNIP1,SYBU,SLC22A4,EXOC7,TIAM1,TRIO,HIRA,HPS4" Drug 3520_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "AP2A2,APBB2,ARRB1,PLA2G4C,MARK4,GYG2,CRLF1,B4GALT6,SH2B1,PPP6R2,MAML1,DAPK3,RUSC2,COPS8,TDRKH,INPP5B,KCNH2,MID1,NEK1,NF1,NFYA,GPSM2,PRKAR1B,RGS12,ZKSCAN3,KDM4C,CAMTA2,POGZ,CEP68,PHLDB1,ARHGEF9,IQCE,CHST8,BHLHB9,SPHK2" Drug 5684_DN Hymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "SRPX,AMH,AMT,APBB2,APLP1,PPP4R4,ARRB1,ADAM15,CA12,CLGN,HOMER3,PDE4DIP,FAM169A,ARMCX2,CDKL3,AHDC1,MSL3,CNTRL,INPP1,MAP4,AFF1,ADAM22,NF1,RIPOR1,NKAIN1,FBXO11,FNDC3A,BTBD7,ZKSCAN3,ZHX3,PBLD,THSD1,TBCEL,ZEB1,TIGD6" Drug 5881_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADCY6,BIN1,CDK10,CDK13,ATP1A3,CAMK2B,CHRNA4,RAB26,HDAC9,SPOCK2,MFAP3L,TOM1,EDN1,HSD17B14,TUBD1,FAM198B,IQCG,DCTN2,TMEM8B,GLUL,PADI2,KIF5A,MGAT3,AFDN,PILRA,ZSCAN2,ZCWPW1,RGS12,PKNOX2,SPP1,SYT1,SMG6,BEX4,TRIO,NT5M" Drug 2712_UP Sulfameter [651-06-9]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA1,PLA2G4C,ARSE,KIF1A,BMP7,CACNA1G,CDO1,RAB26,NCOR2,DZIP3,RIMS2,RIPOR2,EDNRA,VPS13B,RASGRP2,ERBB4,APC2,FHL1,AGAP2,PRELID3A,SCIN,SAMD14,NOVA2,P2RY1,PRPH,CNNM2,RGS12,KLHDC8A,FRMPD1,PKNOX2,IQSEC2,PLCB1,TACR1,ADGRL3,JPH3" Drug 7238_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDC42BPA,EPB41L5,CDC14B,BCL7A,CFLAR,SCARB1,HOMER3,ABCG1,LRIG1,SOCS5,FAM169A,GPRASP1,GIT2,DBN1,PHC2,EZH1,CGREF1,AHDC1,COPS8,HNMT,INPP5B,IPO5,MITF,PDE4A,PRKAR1B,SAMD9,NKAIN1,GTDC1,PPP4R3A,FNBP1,CAMTA2,ASTN2,MCF2L,SATB2,BEX4" Drug 342_UP "novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "CDC42BPA,AZGP1,CNOT8,CNTFR,ENTPD4,HINFP,SEC14L5,C2CD2L,F5,BAIAP2,SEC23B,NSG1,FERMT2,GRIK5,KCNQ3,MAN2A2,MAPT,NF1,PDE4B,GPR173,LRRN3,MAPK10,RMI1,SEMA6D,SH3BP2,SLA,SLC12A2,ZSWIM8,NMNAT2,ZBTB43,TRIM2,CLASP1,PHF24,ZNF24,SLC17A7" Drug 1553_UP Oxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "APBB2,ARNTL,N4BP2L1,BARD1,CCNT1,RIMS2,MED12,FEM1B,APH1A,PRKAG2,PDLIM5,MPP6,KIF5A,KTN1,MYT1,NTRK3,SETD4,SMIM7,CNNM2,PTK2,PTX3,RNASE1,SH3BP2,SLC6A8,KBTBD4,KDM4B,DOP1A,ZSWIM8,TSPYL2,SYN2,MCF2L,MGRN1,SMUG1,FIP1L1,AAAS" Drug 6197_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "MTUS1,SRPX,APC,KSR1,CALB2,THSD7A,CACNA2D2,SLIT2,SIPA1L1,DZIP3,TNK2,HSD17B14,VPS13B,OLFM1,TMEM8B,ALDH1L1,SPACA9,GRM8,GUCY1A1,KCNJ5,NTRK2,OPRL1,SERPINI1,RETREG1,ZSCAN32,PTPN13,RGS12,RYR3,SH3BP2,KDM4B,CLSTN2,ZEB1,ICAM5,VGF,EMSY" Drug 202_DN raloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA2A,ASPA,SYNJ2,WASF1,CALB2,KALRN,CBFA2T2,SCARB1,STOML1,LY86,NCOR2,GREB1,KIAA0586,SRPK3,ERCC2,OLFM1,RUNDC3A,SYNPO,AFF1,NF1,NPY,NTRK3,PLCD1,ZFHX4,RPS6KA2,SNCA,TMCC1,ZSWIM8,ZC3H13,SPTB,ST5,PHLDB1,COBL,EXOC7,SLC17A7" Drug 6261_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ABHD6,AK2,MTMR2,CBFA2T2,PLAA,SGSM2,DNM1,FEM1B,SUGP2,EGFR,EIF5,F8,MSL3,GRB10,MAP4,MBD1,MITF,PLXNB1,NKAIN1,ROBO1,RXRA,NCBP3,FUZ,SMARCA4,RCOR3,SOX3,FNBP1,ZBTB43,TROVE2,ELOVL4,FBXW11,TBL1X,HIRA,EIF4ENIF1,MAP3K12" Drug 1766_DN Cytisine (-) [485-35-8]; Down 200; 21uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG3,NDRG2,AK2,APBA2,CFLAR,BMP7,SYNJ2,CAST,CD86,CSF1,TM9SF4,SPOCK2,GIT2,PDLIM5,DISC1,LILRB4,MAN1B1,ELOVL5,MAP4,OCRL,PFKFB3,PLCD1,PRKAB2,QRICH1,SH3BP2,DZIP1,PEX26,POGZ,ITPRID2,MTMR14,CABIN1,CHST5,UBE3A,ZNF24,UBE3B" Drug 3004_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,MYRF,HAP1,KRIT1,QKI,HOMER3,CRMP1,NCOR2,SIPA1L1,PDE4DIP,HIPK3,EIF1,OLFM1,FHL1,PDLIM5,GPD2,LILRA2,IL6ST,KHK,SMAD1,CNOT4,CCSER2,STRN3,PRKAR1B,DCHS2,ZSCAN32,PTPRN2,NEK11,PEX26,SNCA,CDK19,SYN2,TRPS1,SSBP2,KCNAB1" Drug 4949_DN Naphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA2A,ADRA1D,CDC42BPA,KIF1A,TAOK2,AKAP7,EDNRA,FGFR1,FHL1,DISC1,POLL,PCLO,GRIK5,CACFD1,ITPKB,IPO5,MSI1,ADAM22,NEK1,SETD4,PDE4A,MBOAT7,MAPK7,PRPH,PREX2,SLC6A8,ZBTB43,EXOC7,TRIM2,RPGRIP1L,PCDHA6,SLC44A1,UBTF,VIPR2,ZNF74" Drug 4995_DN Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NME5,OGT,SLC4A4,QKI,PDE4DIP,PPP6R2,ZNF337,DAPK3,DTNA,FCF1,PDLIM5,SRCAP,ZNF276,MBD1,ADAM22,NF1,NFYA,CNOT4,CCSER2,PLEC,PPP5C,PRKAR1B,ZCWPW1,CCDC25,SAFB,EPN2,SMARCA4,SS18,STX1A,EXOC7,TRIM2,TMPO,VGF,LMF1,GAN" Drug 3024_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADORA2A,ADRA1D,TRMT9B,AMPD3,CDK10,AZGP1,CPS1,OSBPL3,EXOG,HIPK3,MRNIP,MTSS1L,ZNF44,ERAP1,SEPT9,SPACA9,GRM8,SLC2A6,NCKAP1L,SMAD1,NFYA,SLC25A23,PLTP,LRP12,PTN,TCP11L1,SCN2B,SEC14L1,FBXW11,TCF4,SYNE1,THRA,CABIN1,UBE3A,ZNF142" Drug 6838_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "RALGAPA1,BCAS1,ATP6V0A1,CFLAR,CAMK2G,KYAT1,PLEKHB1,CSNK1E,CTH,C2CD2L,PHF20L1,DENND4A,FGFR1,FHL1,OGA,ZNF276,CNTRL,IL6ST,MIA2,RETREG1,PRPH,APTX,RGS12,ERC1,TTBK2,DIP2A,AP4E1,BEX4,TRIO,PLPPR2,ZNF45,HPS4,MPPE1,PHTF2,JMJD1C" Drug 6202_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "OGT,CDC42BPA,PPFIA4,APBB2,SLC4A4,CALB2,CH25H,CHRNA4,CSNK1E,PDE4DIP,FAM169A,PLPPR4,TMCC2,HS3ST2,MRNIP,ARMCX1,FHL1,GPR162,GRM2,PRDM5,MMP16,MSI1,MX1,PCDHGC3,CNNM2,MARCH1,RASGRF1,SLC6A11,FAIM2,ZHX3,LHPP,GPR161,ICAM5,UBE3A,ST7" Drug 2381_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NDRG2,ADORA1,SEMA6A,CDC42BPA,APAF1,CDC14B,SPTBN4,ARRB1,ARRB2,GYG2,USP2,ARHGAP33,LARGE1,FAM149A,AATK,CDON,CDKL3,PIPOX,TRAF3IP2,INPP5K,GATM,PRUNE2,MEF2C,NF1,PPARA,CNNM2,GAL3ST4,RNASEL,FERMT1,KDM4B,WSCD1,ICAM5,SSBP2,CLIP2,LAMP5" Drug 3135_UP Alfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "ADCY6,KIF1A,BMP7,HIP1R,LARGE1,TAOK2,SLC4A8,NRG2,NCOR2,ABCG1,CRYM,ARHGEF10,RIMS2,E2F5,CNNM1,F5,DENND2A,ALDH1L1,C2orf72,KCNQ3,MAP4,MID1,MYO6,CNOT4,NECAB2,KLK6,PTPRN2,NEK11,TCP11L1,PREX2,SLC11A1,IZUMO4,DOCK9,VIPR2,SPHK2" Drug 2008_DN Glipizide [29094-61-9]; Down 200; 9uM; HL60; HG-U133A Broad Institute CMAP Down 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "PKP4,CAMK2G,CDC25B,SRSF11,CSNK1E,DCAF8,ZNF804A,TUBD1,OGA,TRAF3IP2,INPP5K,MAP4K5,KCNN1,KIF2A,MAP4,NFYA,PALM,MAPKAP1,PTN,RNASEL,DCUN1D2,NEK11,SAFB,SATB1,ATXN2,DOP1A,ZBTB43,ATP10B,CHST5,ELP5,TSC2,ZNF32,EVI5,ST7,AAAS" Drug 2802_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.26E-03 1.00E+00 3.00E-02 3.38E-01 35 198 "NME5,PLA2G4C,DNAH17,SCAPER,CACNA1I,CACNA2D2,AKAP7,ABI3BP,DCAF4,MBNL2,TNK2,HSD17B14,AFF2,GAD1,GDF9,GFER,PCLO,KCNF1,MAN2A2,MMP16,LYRM9,PALM,PFKFB2,PURG,PRODH,RELN,RPS6KA2,ASAP3,ST6GAL1,SNCA,KDM4B,CABIN1,UCHL1,UPF3A,DNALI1" Disease C0036341 Schizophrenia DisGeNET Curated 2.19E-14 2.31E-10 2.31E-10 2.27E-09 288 1561 "DGCR6,ABCF1,SYN3,ACHE,BRAP,ADORA1,ADORA2A,ADRA1D,C1QTNF3,ALK,APBA2,APC,DDO,ARRB2,PLA2G4C,ASPA,ATP2A2,ALDH7A1,BCHE,RGS9,BID,ARHGEF7,CACNA1B,DDR1,CALB1,CALB2,CALM1,KALRN,CAMK2B,SLC25A14,CBS,KYAT1,CCK,KRIT1,P2RX6,ARHGEF2,SEPT7,DCLK1,ARHGAP33,MAGI1,DLGAP2,DLGAP1,NUMBL,CHGB,CHRNA4,NDST3,NRXN3,PLAA,QKI,SULT4A1,CNR1,PICK1,AKAP5,TBPL1,CLOCK,CREM,ENTPD4,CRHBP,CRMP1,CRY2,CSF2RA,CSNK1E,CNTNAP2,RIMS2,DOCK4,HDAC9,ARHGAP32,HDAC4,DBI,DBN1,ZNF804A,KIAA0319,SNAP91,DLX1,GRIN3A,DMD,DNM1,MED12,SHANK1,SLC12A6,DPYSL2,DRP2,DTNB,EDNRA,SEMA3D,TMTC1,EBI3,EGFR,EGR3,EIF5,EMX2,ENO2,EPHB1,ERBB4,SIRPB1,NRN1,ACSL4,PTK2B,DLC1,KAT8,PPP1R1B,FGFR1,SUCO,AGAP3,FOLH1,PDLIM5,CAMKK2,CSPG5,FYN,MEGF10,GAA,GABBR1,CHL1,GABRB3,GABRG1,GABRG2,GAD1,RAPGEF6,DISC1,CPLX2,CPLX1,GFRA2,PCDH17,GGTA1P,GHR,PPARGC1A,NTNG2,HPGDS,GLUL,KDM2B,GNAL,GNAO1,MCHR1,PCLO,STMN2,GRB10,GRIA2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM8,CIT,GSN,GSTT2,PADI2,ELOVL5,SYNPO,HNMT,HP,HSPA1L,IGF1,IL6R,IL12A,LRRTM1,ITGAM,SLC35G1,KCNB1,KCNH2,KCNN3,KCNQ3,KIF2A,KIF5A,IPO5,LAMA2,LIFR,LIG4,LSAMP,MAP2,MAP6,MARK1,MBNL1,MBP,LRP1B,MPP2,MYO7A,NDP,NEFM,NPY,NPTX1,NRCAM,NTRK2,NTRK3,OPA1,CLDN11,OXTR,P2RX7,P2RY1,TREM2,PAX6,PCDH8,PDE4A,PDE4B,PDE4D,GPR85,ZDHHC8,ABCB1,SERPINI1,NALCN,FXYD1,PMP22,PSAT1,MAGEL2,RETREG2,PPARA,PPP2R2B,PPP3CC,MAPK3,PRODH,RELN,CNNM2,NDUFS7,PSD,LAMA1,BDNF-AS,EML5,RASGRF1,RGS4,RGS12,PBRM1,ALG9,CCDC25,LRRK2,S100B,SAFB,ATXN2,AMBRA1,NLGN1,PKNOX2,SLC6A11,SEPHS1,SLC12A2,TET1,SNAP25,MYO16,SP4,NFASC,LMO3,SST,NEK4,STX1A,STXBP1,PLCB1,SYN1,ARC,SYN2,SYP,ASTN2,TACR1,TAL1,TCF4,DICER1,SIRT1,ZFPM2,TIMP4,TLR4,NR2E1,CSMD1,CABIN1,RASD2,NPL,PDSS1,AMACR,TSC1,TSC2,UGT8,VGF,VIPR2,VLDLR,VSNL1,XRCC4,ZIC2,ZNF74,SLC30A3,SLC38A1,HPS4,SLC17A7,WNK3,NELFE,PLSCR4,FZD3,RTN4,HNRNPA3,ADAMTSL3,ADAMTS10,NETO1,ST8SIA2" Disease C0005586 Bipolar Disorder DisGeNET Curated 3.74E-12 3.94E-08 1.34E-08 1.32E-07 153 730 "SYN3,ADCY8,BRAP,ADRB2,AGT,SORCS2,DPP10,ARNTL,ARRB2,ATP1A1,ATP1A3,ATP2A2,BCHE,BID,SYNJ1,ARHGEF7,WASF1,CACNA1A,CACNA1B,CALB1,CAMK2A,HIP1R,CBS,CCK,P2RX6,DCLK1,MAGI1,NDST3,CNR1,WHRN,CLOCK,CREM,CRHBP,CRY2,NCOR2,ABCG1,SEC24C,ARHGEF10,CSNK1E,CNTNAP2,PLCXD3,DGKB,DBN1,ZNF804A,DLX1,GRIN3A,SLC12A6,DPYSL2,DRP2,TOM1,EDNRA,RASGRP1,EGFR,EGR3,EMX2,ERBB4,NRN1,ACSL4,PTK2B,RACK1,PPP1R1B,FGFR1,FOXO3,NBEA,PDLIM5,CAMKK2,FYN,GABRA3,CHL1,GABRB3,GABRG1,GAD1,DISC1,CPLX2,CPLX1,TUBA8,NTNG2,HPGDS,GNAL,MCHR1,PCLO,GRIA2,GRIK4,GRIK5,GRIN2C,IGF1,INPP1,ITGAM,KCNN3,KCNQ3,MAP2,MAPT,DBNL,NEFM,NFIX,NPTX1,NTRK2,P2RX7,P2RY1,PDE4A,PDE4B,PFKFB3,ZDHHC8,ABCB1,POLG,MINDY2,PPP2R2C,PPP3CC,MAPK3,PRODH,RELN,PSD,BDNF-AS,RASGRF1,RGS4,PRIMA1,PBRM1,RORB,S100B,SCN8A,FNDC3A,NLGN1,SNAP25,MBD5,DOK5,SP4,LMO3,SST,NEK4,PLCB1,SYN2,SYP,ASTN2,TACR1,TCF4,CUX2,RPGRIP1L,SYNE1,DOCK9,SIRT1,ZNF34,TLR4,NR2E1,CSMD1,NPL,TRPM2,UBC,VGF,VIPR2,SLC17A7,MPPE1,RTN4,ST8SIA2" Disease C3714756 Intellectual Disability DisGeNET Curated 3.82E-12 4.02E-08 1.34E-08 1.32E-07 215 1131 "DGCR6,PTCHD1,ADRB2,PCDH19,CC2D2A,AMH,AMT,CDC42BPA,KCNAB2,APC,CASK,ARHGDIA,ASPA,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,SCAPER,CACNA1G,WASF1,CA4,CA8,CACNA2D1,CAMK2A,RUNX1T1,CBS,CD38,AP4M1,ARHGEF2,LARGE1,NOG,NRXN3,ABCG2,ARHGEF6,CPS1,SH2B1,RGS6,CNTNAP2,RIMS2,RUBCN,HDAC4,KIAA0586,DBN1,DBT,ZBTB24,SACS,DLX1,RAB39B,DMD,DNM1,MED12,SHANK1,SLC12A6,DPH1,DPP6,RCAN1,WDPCP,FRY,AASS,ELN,EMX2,VPS13B,ERCC2,APC2,EYA1,ACSL4,TUBB3,FKTN,ZNF589,FGF13,FGFR1,FGFR3,MAD2L2,SEC23B,AFF2,COQ5,POMT1,AP4B1,CHL1,GABRB3,GAD1,DISC1,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,NTNG2,RNPS1,GPT2,GPD2,GRIA2,GRIK4,HBA1,MAN1B1,HNMT,ZDHHC15,AGFG1,IDH3B,IGF1,TMEM240,IL12A,SLC6A17,ITGA7,KCNQ3,L1CAM,LAMA2,LAMP2,LIG4,MAPT,MEF2C,MEIS2,MID1,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,NF1,NFIX,NRCAM,OCRL,CHAMP1,OPA1,PAX6,PDE4D,NLGN3,NALCN,MAGEL2,PPP2R2B,KANSL1,MAPK10,PRODH,MASP1,CNNM2,LAMA1,PIGG,PTCH1,PEX2,QDPR,RBBP8,RET,PRRT2,UBR7,KIF7,SETD5,TMLHE,CARF,ELP2,ZC3H14,CLIP1,SALL1,SCN8A,FOXRED1,ARX,CNKSR2,SLC6A8,SMARCA4,CDK5RAP2,SNAP25,MBD5,SNRPN,MYO16,SOX3,SOX11,ZNF423,ARHGAP26,SPTAN1,IQSEC2,POGZ,ZC4H2,KANK1,STXBP1,ARHGEF9,SYP,SYT1,CAMTA1,TAL1,TCF4,DMXL2,SATB2,RPGRIP1L,SZT2,NSD1,DICER1,AP4E1,THRA,ASXL3,KAT6B,TRIO,TRPS1,TSC1,TSC2,HIRA,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,ZNF711,FTSJ1,TUBA1A,NELFE,DOCK8,KAT6A,JMJD1C,NLRP3,SNX14,AAAS,FXR1,GAN" Disease C0004352 Autistic Disorder DisGeNET Curated 2.90E-10 3.06E-06 7.65E-07 7.52E-06 133 644 "DGCR6,ADORA2A,PTCHD1,ADRB2,PCDH19,AGT,PCDH10,APBA2,KCNAB2,APC,CASK,ATP2B2,DOCK11,MPDZ,NRP2,CACNA1G,CACNA1A,CBS,CD38,ARHGEF2,DLGAP2,CHRNA4,NRXN3,MAGED1,CLOCK,SH2B1,CS,CNTNAP2,DOCK4,ARHGAP32,KATNAL2,ZNF804A,FAM107B,DLX1,RAB39B,DMD,MED12,SHANK1,SLC12A6,DPYSL2,DRP2,SEZ6L2,ELN,VPS13B,ACSL4,AFF2,NBEA,GABBR1,GABRA3,CHL1,GABRB3,GABRG1,GAD1,DISC1,GATM,GHR,NTNG2,HPGDS,GLUL,GPR37,PCLO,GRIA2,GRIK4,GRM8,IGF1,INPP1,SLC35G1,KCND2,GPR155,MAP2,MARK1,MBD1,MBP,MEF2C,SCAMP5,NF1,NPTX2,NRCAM,NTRK2,OGG1,OXTR,CNTN3,PAX6,PCDH9,PDE4A,PDE4B,PDE4D,NLGN3,JAKMIP1,MAGEL2,POLG,PRKCB,MAPK3,HYDIN,PRODH,RELN,PSD,SH3TC2,RASGRF1,TMLHE,ROBO1,ROBO2,CLIP1,SCN7A,SCN8A,ARX,NLGN1,SLC6A8,SNAP25,MBD5,SNRPN,SST,STX1A,STXBP1,SYN1,SYN2,ASTN2,TCF4,NSD1,RNF216P1,TSC1,TSC2,UBE2H,UBE3A,VLDLR,CLIP2,XPO1,CADM2,WNK3,JMJD1C,FXR1,NETO1,ST8SIA2" Disease C0014544 Epilepsy DisGeNET Curated 5.38E-10 5.67E-06 1.13E-06 1.12E-05 181 962 "ACADM,ADRA1D,PCDH19,SPARCL1,SEMA6A,PCDH10,AMPD2,AMT,ANK2,APBA2,KCNAB2,CASK,ASPA,ATP1A3,ATP2A2,ADAM23,MPDZ,HCN2,BCS1L,NRP2,CFLAR,SYNJ1,ST3GAL5,SGCE,CA8,CACNA1A,CACNA2D1,CACNB4,CALM1,CBS,KRIT1,AP4M1,LARGE1,CHRNA4,SLIT2,TPP1,ABCG2,CNN3,CNR1,RTTN,SLC35F1,CPS1,PREPL,SH2B1,CNTNAP2,RUBCN,HDAC9,HDAC4,DBT,ZNF804A,DLX1,RAB39B,DMD,DNM1,MED12,SLC12A6,ABCC5,EGR3,AASS,TNK2,ELN,EMX2,GPHN,ERBB4,ERCC2,ADGRV1,FKTN,STRADA,FGF13,FGFR1,FGFR3,POMT1,STAMBP,AP4B1,GABBR1,GABRA3,GABRB3,GABRG2,GAD1,GALC,CPLX1,GCK,TUBGCP4,TUBA8,MMADHC,GLI2,GLUL,GNAO1,PCLO,GRIA2,GRIN2C,GRM2,GRM8,MAN1B1,HP,KCNB1,KCND2,KCNH2,KCNK3,KCNQ3,KIF2A,KIF5A,L1CAM,LAMA2,MAPT,MEF2C,ADAM22,MYH3,MYO5A,NDP,NFE2L2,NPY,OCRL,TREM2,PAX6,ABCB1,SERPINI1,PSAT1,POLG,PPM1B,RELN,CNNM2,PTCH1,PEX2,QDPR,RET,PRRT2,LGI2,STX1B,SCN2B,SCN7A,SCN8A,FOXRED1,SGK1,ARX,SLC4A3,PEX26,SLC6A8,CCDC88A,SLC12A2,NAPB,SMARCA4,MBD5,SNRPN,SOX3,SOX11,SPTAN1,IQSEC2,SSTR1,SSTR2,STX1A,STXBP1,ARHGEF9,VPS13A,PLCB1,SYN1,SYN2,TCF4,SATB2,SZT2,NSD1,AP4E1,TK2,TLR4,KAT6B,SMUG1,TRPM2,TSC1,TSC2,TUBB2A,UBE3A,UGT8,VLDLR,RBFOX3,ELFN1,CELF4,TUBA1A,SLC17A7,KCNAB1,EPM2A,AAAS" Disease C0036572 Seizures DisGeNET Curated 2.82E-09 2.97E-05 4.95E-06 4.88E-05 181 982 "ACADM,ACHE,ADORA2A,ADRA1B,ADRB2,PCDH19,AGT,CC2D2A,AMPD2,AMPH,AMT,KCNAB2,CASK,ASPA,ATP2A2,ALDH7A1,ADAM23,MPDZ,BCHE,BCS1L,NRP2,SYNJ1,ARHGEF7,SGCE,CA8,CACNA1A,CALB1,CBS,CCK,KRIT1,AP4M1,LARGE1,CHRNA4,SLIT2,TPP1,CNR1,RTTN,CPS1,PREPL,CREM,SH2B1,CRMP1,CNTNAP2,RUBCN,HDAC4,DBT,ZNF804A,DNM1,MED12,SLC12A6,DNM1L,SEZ6L2,EDN1,EDN3,EGFR,EGR3,AASS,EMX2,GPHN,ERCC2,ADGRV1,EYA1,NRN1,FCGR3A,FKTN,FGF13,FGFR1,FGFR3,BAIAP2,AFF2,POMT1,STAMBP,AP4B1,GABBR1,GABRG2,GAD1,GALC,CPLX1,GCK,TUBGCP4,TUBA8,MMADHC,GLI2,GLUL,GNAO1,PCLO,GRIA2,GRIN2C,GRM2,GRM8,AP4S1,MAN1B1,JAK2,KCND2,KCNH2,KCNQ3,KIF2A,L1CAM,LAMA2,MAPT,MBNL1,MEF2C,ADAM22,MYH3,MYO5A,NDP,NPY,OCRL,TREM2,ABCB1,SERPINI1,PSAT1,POLG,PPM1B,MAPK3,MAPK10,PRODH,RELN,CNNM2,PIGG,PTCH1,PEX2,QDPR,RET,PRRT2,STX1B,ATXN2,SCN8A,FOXRED1,ARX,CNKSR2,PEX26,SLC6A8,SLC8A1,CCDC88A,SLC12A2,SMARCA4,MBD5,SNRPN,MYO16,SOX3,SOX11,SPTAN1,IQSEC2,LMO3,SST,SSTR2,STXBP1,ARHGEF9,VPS13A,SYN1,SYN2,TCF4,SATB2,SZT2,SLC19A3,AP4E1,TIMP4,TK2,TLR4,KAT6B,CABIN1,TNS1,SMUG1,TSC1,TSC2,TUBB2A,UBE3A,UGT8,PDIA2,VLDLR,RBFOX3,ELFN1,ANKS1B,SLC30A3,MFF,DNALI1,TUBA1A,SLC17A7,SNX14,AAAS" Disease C0233514 Abnormal behavior DisGeNET Curated 3.64E-09 3.84E-05 5.48E-06 5.40E-05 84 365 "BRAP,ADRB2,SEMA6A,ARRB2,ALDH7A1,ARHGEF7,SGCE,CALB1,HAP1,CCK,DCLK1,MAGI1,CHRNA4,QKI,SULT4A1,CNR1,CLOCK,HDAC9,HDAC4,DBI,DCTN1,ZNF804A,PLPPR4,DMD,MED12,DPYSL2,TMTC1,EGR3,ERBB4,BAIAP2,MEGF10,GABRA3,GABRG2,DISC1,MMADHC,GRM2,LINGO1,SLC6A17,L1CAM,STMN1,MAP6,MAPT,MARK1,MBNL1,NRCAM,NTRK2,OXTR,TREM2,PDE4B,GPR85,NLGN3,MAGEL2,POLG,PPP2R2B,RELN,PSD,PEX2,LRRK2,S100B,LRFN5,SCN8A,PEX26,SMARCA4,SNAP25,SP4,GLT8D1,LMO3,POGZ,STX1A,STXBP1,VPS13A,SYN1,CAMTA1,NSD1,NR2E1,CSMD1,SMUG1,TSC1,TSC2,VGF,ZIC1,ZIC2,CELF4,ST8SIA2" Disease C0338656 Impaired cognition DisGeNET Curated 7.81E-09 8.23E-05 1.03E-05 1.01E-04 125 625 "ACHE,PCDH19,AMPH,BIN1,APBB2,APOC1,KIF1A,BCHE,SYNJ1,CACNA1A,CAMK2A,CAPN3,RUNX1T1,CBR1,CBS,DCLK1,LARGE1,CDR1,NOG,CRLF1,CHN1,CHRNA4,ARHGAP22,FBXO7,SULT4A1,CNR1,COL4A5,CLOCK,CRMP1,CSF1R,CNTNAP2,CYBB,HDAC9,DBN1,RAB39B,DMD,DNM1L,AASS,ENO2,ERCC2,NRN1,FKTN,FGF14,FGFR3,BAIAP2,PRKAG2,SEC23B,POMT1,CELF1,OGA,FYN,CHL1,GAD1,DISC1,CPLX2,CYP46A1,GLUL,GRIA2,ADAMTS13,GRM2,HP,AGFG1,IGF1,IL6R,TMEM240,ITGA7,LAMA2,LAMP2,MAP2,MAPT,MEF2C,MX1,NF1,NFE2L2,NFIX,NOVA2,SETD4,OCRL,OXTR,TREM2,PDE4A,PDE4D,ABCB1,PMP22,POLG,PRODH,RELN,VPS13C,APTX,PEX2,RBBP8,LRRK2,S100B,SCN8A,COPZ1,PEX26,SLC6A8,SNAP25,SNCA,NMNAT2,SPP1,SPART,CLSTN2,SST,SYP,ASTN2,TCF4,SATB2,CRTC1,SIRT1,TLR4,NR2E1,SMUG1,NEIL2,TSC1,VLDLR,VSNL1,RBFOX3,CLIP2,XRCC4,FTSJ1,EPM2A,GJC2,NLRP3,AP3B2" Disease C0025362 Mental Retardation DisGeNET Curated 5.58E-08 5.88E-04 6.32E-05 6.22E-04 161 885 "DGCR6,PCDH19,CC2D2A,AMH,AMT,CDC42BPA,KCNAB2,APC,CASK,ARHGDIA,ASPA,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,WASF1,CA4,CA8,RUNX1T1,CBS,CD38,LARGE1,ABCG2,ARHGEF6,CPS1,SH2B1,RGS6,CNTNAP2,RIMS2,RUBCN,HDAC4,KIAA0586,DBN1,DBT,ZBTB24,SACS,DLX1,RAB39B,DMD,DNM1,MED12,SLC12A6,DPP6,RCAN1,WDPCP,AASS,ELN,EMX2,VPS13B,ERCC2,APC2,EYA1,ACSL4,FKTN,FGF13,FGFR1,FGFR3,MAD2L2,SEC23B,AFF2,POMT1,CHL1,GABRB3,GAD1,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,RNPS1,GPD2,GRIK4,HBA1,AGFG1,IDH3B,IGF1,TMEM240,IL12A,ITGA7,L1CAM,LAMA2,LAMP2,LIG4,MAPT,MEIS2,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,NF1,NFIX,NRCAM,OCRL,OPA1,PAX6,PDE4D,NLGN3,MAGEL2,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,QDPR,RBBP8,RET,PRRT2,SETD5,SALL1,SCN8A,FOXRED1,ARX,CNKSR2,SLC6A8,SMARCA4,CDK5RAP2,SNAP25,SNRPN,SOX3,SOX11,ZNF423,ARHGAP26,IQSEC2,POGZ,KANK1,STXBP1,ARHGEF9,SYP,SYT1,TAL1,TCF4,DMXL2,SATB2,RPGRIP1L,NSD1,DICER1,THRA,KAT6B,TRPS1,TSC1,TSC2,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,ZNF711,FTSJ1,TUBA1A,NELFE,KAT6A,NLRP3,AAAS,FXR1,GAN" Disease C1510586 Autism Spectrum Disorders DisGeNET Curated 6.00E-08 6.32E-04 6.32E-05 6.22E-04 92 436 "DGCR6,ADORA2A,PTCHD1,PCDH19,AMT,DPP10,APBA2,APC,CASK,ATP2B2,MPDZ,CACNA1G,CACNA1A,CARS,CD38,CDH2,TAOK2,NRXN3,SH2B1,CNTNAP2,ARHGAP24,ZNF804A,KIAA0319,DLX1,RAB39B,DNM1,SHANK1,DPP6,SEZ6L2,KMT5B,VPS13B,GPHN,ERBB4,BAIAP2,AFF2,NBEA,GABRB3,GABRG1,GAD1,SRRM4,GPR37,GRIK4,GRM8,ICA1,L1CAM,LIG4,GPR155,MARK1,MEF2C,NEXMIF,ZNF713,OXTR,PAX6,PCDH9,NLGN3,JAKMIP1,MAGEL2,LRRN3,CEP41,PRKCB,MAPK10,RELN,PSD,BDNF-AS,PRRT2,TMLHE,ARX,NLGN1,SLC6A8,TET1,SNAP25,MBD5,MYO16,ZNF423,POGZ,PLCB1,SYN1,SYN2,ASTN2,TBL1X,TCF4,SATB2,SYNE1,HEY1,TRIO,TSC1,TSC2,UBE3A,XPO1,JMJD1C,ST8SIA2,GAN" Disease C0525045 Mood Disorders DisGeNET Curated 1.08E-07 1.13E-03 9.50E-05 9.35E-04 71 313 "ACHE,NDRG2,ADCY8,ADORA2A,ADRA1B,ADRB2,ARNTL,ARRB2,ATP2A2,DST,ARHGEF7,P2RX6,CBFA2T2,CDH2,CNR1,CLOCK,CRHBP,CRY2,ABCG1,RGS6,SEC24C,HDAC9,HDAC4,DCTN1,ZNF804A,DMD,EDN1,PPP1R1B,FOXO3,GABRA3,CHL1,GAD1,DISC1,RNPS1,HPGDS,GLI2,GLUL,MCHR1,PCLO,TPPP,GRM2,HP,MAP2,NPY,NTRK2,NTRK3,TBC1D25,P2RX7,P2RY1,PAX6,PFKFB3,PIK3R1,SMOX,MAGEL2,POLG,RELN,S100B,HES6,SIRT2,ATF7IP,SST,VPS13A,PLCB1,TACR1,CRTC1,SIRT1,ZNF34,VGF,VIPR2,FZD3,ST8SIA2" Disease C1263846 Attention deficit hyperactivity disorder DisGeNET Curated 1.08E-07 1.14E-03 9.50E-05 9.35E-04 76 343 "SYN3,AS3MT,ADORA2A,PTCHD1,ADRA1B,ARNTL,BCHE,NRP2,KALRN,KYAT1,DCLK1,CHRNA4,CNR1,CNTFR,CLOCK,SH2B1,SEC24C,CNTNAP2,ZNF804A,SPOCK3,DMD,MED12,SLC12A6,DPP6,EDNRA,ELN,EPHB1,ERBB2,PPP1R1B,BAIAP2,DISC1,CPLX2,GP1BB,GRM8,IGF1,KCNJ5,LIG4,MARK1,GIT1,MYCN,MYT1,NF1,NPY,NTRK2,NTRK3,OCRL,OXTR,PRTG,PDE4D,MAGEL2,DIRAS2,BDNF-AS,PTPRD,PTPRN2,S100B,SCN8A,SLC6A8,SNAP25,SNRPN,IQSEC2,LMO3,STX1A,VPS13A,SYP,ASTN2,TACR1,ADGRL3,NSD1,TSC1,TSC2,HIRA,UBE3A,VIPR2,CLIP2,ELFN1,MKRN3" Disease C0003467 Anxiety DisGeNET Curated 3.02E-07 3.18E-03 2.45E-04 2.41E-03 89 432 "DGCR6,ASIC1,ACHE,NDRG2,ADCY5,ADORA1,ADORA2A,ADRB2,AGT,SRPX,APC,ARRB2,ATP1A3,SGCE,BAIAP3,CACNA1A,CCK,CHRNA4,FBXO7,CNR1,MAGED1,CREM,CRHBP,SLITRK5,MATR3,DBI,DCTN1,ZNF804A,SHANK1,RCAN1,EDN1,OPTN,TENM1,ELN,GPHN,ERBB4,EYA1,F8,FGFR1,FOLH1,CAMKK2,FYN,GABRB3,GABRG2,GAD1,PPARGC1A,GLI2,MCHR1,GRIA2,GRM8,IGF1,STMN1,MAPT,NDP,NEFH,NFIX,NPY,NTRK2,NTRK3,NUCB2,OCRL,OXTR,TREM2,PDE4B,ABCB1,NLGN3,PMP22,PPP2R2B,PRODH,PRPH,BDNF-AS,LRRK2,S100B,ATXN2,ATF7IP,MBD5,SSPO,ARHGEF9,VPS13A,SYN1,TACR1,TAL1,SIRT1,TRPM2,TSC2,RBFOX3,CLIP2,SLC38A1,AAAS" Disease C0009241 Cognition Disorders DisGeNET Curated 4.37E-07 4.60E-03 3.29E-04 3.23E-03 56 235 "ACHE,AGT,AMPH,BCHE,SYNJ1,RUNX1T1,CBR1,CBS,CDR1,NOG,CHRNA4,CNR1,HDAC9,DBN1,DMD,ENO2,NRN1,FGF14,BAIAP2,CHL1,GAD1,DISC1,GLUL,AGFG1,IGF1,MAPT,NF1,NOVA2,SETD4,OXTR,MAPK10,RELN,LRRK2,S100B,SCN8A,SNAP25,SNCA,NMNAT2,SPP1,SPART,SST,SYP,ASTN2,TCF4,SATB2,TLR4,SMUG1,TSC1,UBE3A,VLDLR,VSNL1,RBFOX3,CLIP2,EPM2A,NLRP3,AP3B2" Disease C0278124 Absent tendon reflex DisGeNET Curated 9.46E-07 9.97E-03 5.87E-04 5.77E-03 29 93 "ADCY6,BIN1,ATP1A3,KIF1A,DST,LARGE1,CFL2,CNTN1,DCAF8,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,SBF1,SNAP25,VPS13A,TRIM2,PIK3R5,PDSS1,GAN" Disease C0234146 Absent reflex DisGeNET Curated 9.46E-07 9.97E-03 5.87E-04 5.77E-03 29 93 "ADCY6,BIN1,ATP1A3,KIF1A,DST,LARGE1,CFL2,CNTN1,DCAF8,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,SBF1,SNAP25,VPS13A,TRIM2,PIK3R5,PDSS1,GAN" Disease C0241772 "Reflex, Deep Tendon, Absent" DisGeNET Curated 9.46E-07 9.97E-03 5.87E-04 5.77E-03 29 93 "ADCY6,BIN1,ATP1A3,KIF1A,DST,LARGE1,CFL2,CNTN1,DCAF8,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,SBF1,SNAP25,VPS13A,TRIM2,PIK3R5,PDSS1,GAN" Disease C0003469 Anxiety Disorders DisGeNET Curated 2.31E-06 2.43E-02 1.35E-03 1.33E-02 78 382 "DGCR6,ASIC1,ACHE,NDRG2,ADORA1,ADORA2A,ADRB2,AGT,SRPX,APC,ARRB2,SGCE,BAIAP3,CALM1,CCK,CHRNA4,FBXO7,QKI,CNR1,MAGED1,CLOCK,CREM,CRHBP,CRY2,SLITRK5,DBI,ZNF804A,SHANK1,RCAN1,EDN1,TENM1,GPHN,ERBB4,EYA1,F8,FOLH1,CAMKK2,FYN,GABRB3,GABRG2,GAD1,DISC1,PPARGC1A,GLI2,MCHR1,GRIA2,GRM8,IGF1,STMN1,LSAMP,NPY,NTRK2,NTRK3,NUCB2,TBC1D25,OXTR,P2RX7,PDE4B,ABCB1,NLGN3,PMP22,PSAT1,PRODH,BDNF-AS,LRRK2,S100B,ATF7IP,MBD5,SSPO,ARHGEF9,SYN1,TACR1,TAL1,SIRT1,TRPM2,TSC2,RBFOX3,SLC38A1" Disease C0557874 Global developmental delay DisGeNET Curated 3.43E-06 3.61E-02 1.90E-03 1.87E-02 134 757 "ACADM,PCDH19,AMPD2,KCNAB2,APC,CASK,ARSE,ASPA,ATP1A3,ALDH7A1,KIF1A,BBS2,BCS1L,ST3GAL5,AP4M1,ZBED1,LARGE1,COL11A2,CPS1,PREPL,SH2B1,SEC24C,HDAC4,KIAA0586,DGKB,ZBTB24,DMD,MED12,CDON,SLC12A6,DPH1,EDNRB,EMX2,ERBB4,ERCC2,APC2,EYA1,F5,TUBB3,FKTN,FGFR1,FGFR3,MAD2L2,SEC23B,POMT1,AP4B1,GABRG2,GAD1,CPLX1,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,NFU1,GFER,MMADHC,GLI2,GNAO1,GP1BB,PCLO,CIT,AP4S1,MAN1B1,IGF1,KCNB1,KCNQ3,KIF2A,LAMP2,LIG4,MAPT,MBP,MEF2C,MEIS2,MID1,MYO5A,MYO7A,NF1,NTRK2,OCRL,PAX6,PCDH8,PDE4D,PMP22,PSAT1,MAGEL2,POLG,PPM1B,PRODH,CNNM2,PTCH1,PTK2,PEX2,QDPR,RET,SETD5,ALG9,SCN8A,FOXRED1,PUF60,PEX26,SLC6A8,SMARCA4,SNAP25,SNRPN,SOX3,SOX11,ZNF423,SPART,POGZ,NKAIN2,STXBP1,CAMTA1,TCF4,SATB2,RPGRIP1L,SZT2,DICER1,AP4E1,ASXL3,KAT6B,TSC1,TSC2,TUBB2A,HIRA,UBE3A,VLDLR,XRCC4,ZIC2,MKRN3,UBE3B,KAT6A,AAAS" GO: Molecular Function GO:0015267 channel activity 6.94E-13 1.02E-09 5.47E-10 4.30E-09 61 470 "TTYH1,ASIC1,KCNIP2,RYR1,TOMM40L,SCN3A,SCN4B,SCNN1D,ASIC4,RASA3,AQP4,SLC14A1,SNAP25,SCN3B,FXYD6,GJB1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,BEST1,KCNT2,TOMM20,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,ABCC9,CACNG7" GO: Molecular Function GO:0022803 passive transmembrane transporter activity 7.62E-13 1.12E-09 5.47E-10 4.30E-09 61 471 "TTYH1,ASIC1,KCNIP2,RYR1,TOMM40L,SCN3A,SCN4B,SCNN1D,ASIC4,RASA3,AQP4,SLC14A1,SNAP25,SCN3B,FXYD6,GJB1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,BEST1,KCNT2,TOMM20,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,ABCC9,CACNG7" GO: Molecular Function GO:0022838 substrate-specific channel activity 1.12E-12 1.64E-09 5.47E-10 4.30E-09 58 438 "TTYH1,ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,RASA3,AQP4,SLC14A1,SNAP25,SCN3B,FXYD6,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,BEST1,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,ABCC9,CACNG7" GO: Molecular Function GO:0005216 ion channel activity 3.09E-12 4.53E-09 1.13E-09 8.91E-09 56 424 "TTYH1,ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,RASA3,SNAP25,SCN3B,FXYD6,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,BEST1,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,ABCC9,CACNG7" GO: Molecular Function GO:0022836 gated channel activity 3.98E-12 5.84E-09 1.17E-09 9.18E-09 48 331 "ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,RASA3,SNAP25,SCN3B,ABCC8,ANO4,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,KCNK10,ANO5,ASIC3,CHRNB2,BEST1,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,CACNG7" GO: Molecular Function GO:0046873 metal ion transmembrane transporter activity 1.16E-10 1.70E-07 2.83E-08 2.23E-07 53 426 "TTYH1,ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,ABCC8,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIN1,TF,KCNK10,PDE2A,ASIC3,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9,SLC6A15,SLC39A12,CACNG7" GO: Molecular Function GO:0022857 transmembrane transporter activity 1.08E-09 1.58E-06 2.26E-07 1.77E-06 92 1014 "TTYH1,ASIC1,KCNIP2,RYR1,SLC44A5,TOMM40L,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC2A5,SLC6A9,SLC8A2,SLC8A3,SLC14A1,SLCO1A2,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,FXYD6,GJB1,SLCO1C1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,TF,MFSD2A,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,SLC22A6,BEST1,SLC36A4,KCNT2,SLC45A1,TOMM20,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,SV2A,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,SLC17A6,SLC25A18,ABCC9,SLC6A15,SFXN5,SLC39A12,SIDT2,CACNG7,SLC4A10" GO: Molecular Function GO:0008092 cytoskeletal protein binding 1.70E-09 2.49E-06 2.79E-07 2.19E-06 83 886 "EPS8,MAP6,MAPT,APC2,RCSD1,ACTN2,ADGRV1,CLIP1,ADD3,ERMN,SGIP1,ANK1,ANK2,ANK3,APBB1,APC,GAS7,SORBS1,SYBU,JAKMIP3,SHTN1,CLSTN1,PKNOX2,CCDC88A,SNAP25,SNCB,FYN,PALLD,MYBPC1,KIF21B,MYH7,NEK6,KIF1B,CLASP2,GNAS,CAMSAP2,CDK5R2,PSRC1,KLHL4,CACNB2,NUMA1,GRIA1,DAAM2,TNS1,TPM3,TPM4,MAGI1,PDE4B,HNRNPK,HPCA,ANLN,CCSER2,MICAL1,SPATA6,PACSIN1,ATCAY,CRMP1,FEZ1,MICAL2,PHACTR3,FMN2,MAPK8,DPYSL5,SPIRE1,JAKMIP2,LRP8,STMN4,BLOC1S6,KCNA2,KCNC1,KCNJ11,KCNMA1,KCNQ2,KIF2A,WIPF2,DNM2,ABI1,USH1C,TTLL7,ABI2,EPB41,EPB41L1,EPB41L2" GO: Molecular Function GO:0005261 cation channel activity 1.71E-09 2.51E-06 2.79E-07 2.19E-06 41 306 "ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,RASA3,SNAP25,SCN3B,ABCC8,CACNA1A,GPM6A,CACNA1E,CACNB2,GRIN1,P2RX7,KCNK10,PDE2A,ASIC3,CHRNB2,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9,CACNG7" GO: Molecular Function GO:0022843 voltage-gated cation channel activity 2.16E-09 3.16E-06 3.16E-07 2.49E-06 26 141 "KCNIP2,RYR1,SNAP25,ABCC8,CACNA1A,CACNA1E,CACNB2,GRIN1,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,CACNG7" GO: Molecular Function GO:0015075 ion transmembrane transporter activity 4.21E-09 6.17E-06 5.61E-07 4.42E-06 81 873 "TTYH1,ASIC1,KCNIP2,RYR1,SLC44A5,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,SLCO1A2,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,FXYD6,SLCO1C1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,TF,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,SLC22A6,BEST1,SLC36A4,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,SLC17A6,ABCC9,SLC6A15,SFXN5,SLC39A12,CACNG7,SLC4A10" GO: Molecular Function GO:0022832 voltage-gated channel activity 1.58E-08 2.32E-05 1.79E-06 1.41E-05 30 198 "KCNIP2,RYR1,SCN3A,SCN4B,SNAP25,SCN3B,ABCC8,CACNA1A,CACNA1E,CACNB2,GRIN1,KCNK10,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,CACNG7" GO: Molecular Function GO:0005244 voltage-gated ion channel activity 1.58E-08 2.32E-05 1.79E-06 1.41E-05 30 198 "KCNIP2,RYR1,SCN3A,SCN4B,SNAP25,SCN3B,ABCC8,CACNA1A,CACNA1E,CACNB2,GRIN1,KCNK10,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,CACNG7" GO: Molecular Function GO:0005249 voltage-gated potassium channel activity 3.91E-08 5.73E-05 4.09E-06 3.22E-05 19 91 "KCNIP2,SNAP25,ABCC8,KCNT2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2" GO: Molecular Function GO:0005267 potassium channel activity 5.61E-08 8.23E-05 5.48E-06 4.32E-05 22 122 "KCNIP2,SNAP25,ABCC8,KCNK10,KCNT2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9" GO: Molecular Function GO:0022890 inorganic cation transmembrane transporter activity 8.01E-08 1.18E-04 7.28E-06 5.73E-05 55 542 "TTYH1,ASIC1,KCNIP2,RYR1,SLC44A5,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,ABCC8,CACNA1A,GPM6A,CACNA1E,CACNB2,AZIN2,GRIN1,TF,KCNK10,PDE2A,ASIC3,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9,SLC6A15,SLC39A12,CACNG7" GO: Molecular Function GO:0005516 calmodulin binding 8.69E-08 1.28E-04 7.28E-06 5.73E-05 28 190 "MAP6,RYR1,ADD3,SCN3A,PLA2G6,SLC8A2,SLC8A3,ATP2B2,MYH7,ENKUR,ARPP21,CAMSAP2,CACNA1A,NRGN,CAMK2A,CAMK2G,GRIN1,TJP1,PDE1A,PDE1C,PHKG1,CAMKV,PPP3CB,KCNH1,KCNN3,KCNQ2,CAMK1G,EPB41" GO: Molecular Function GO:0015079 potassium ion transmembrane transporter activity 8.93E-08 1.31E-04 7.28E-06 5.73E-05 24 146 "KCNIP2,SNAP25,ATP1A2,ATP1A3,ABCC8,KCNK10,KCNT2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9" GO: Molecular Function GO:0044325 ion channel binding 1.18E-07 1.73E-04 9.11E-06 7.17E-05 22 127 "ACTN2,KCNIP2,SCN4B,FHL1,ANK2,ANK3,ASPH,SNAP25,FYN,SCN3B,ABCC8,HAP1,PDE4B,PIRT,RIMS4,RIMS3,KCNC1,KCND3,KCNH1,KCNJ11,GOPC,ABCC9" GO: Molecular Function GO:0008324 cation transmembrane transporter activity 8.04E-07 1.18E-03 5.89E-05 4.64E-04 59 642 "TTYH1,ASIC1,KCNIP2,RYR1,SLC44A5,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,ABCC8,CACNA1A,GPM6A,CACNA1E,CACNB2,AZIN2,GRIN1,ATP13A2,TF,P2RX7,KCNK10,PDE2A,ASIC3,CHRNB2,SLC36A4,KCNT2,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9,SLC6A15,SLC39A12,CACNG7" GO: Molecular Function GO:0005509 calcium ion binding 1.03E-06 1.50E-03 7.16E-05 5.63E-04 63 708 "TTYH1,CDHR1,SYT9,ACTN2,ADGRV1,KCNIP2,SLC25A25,RYR1,HPCAL4,ITSN1,ANXA7,CLSTN1,RPH3A,CADPS,CGREF1,SLIT1,DLL3,ASPH,SNCB,ATP2B2,CAB39,DNER,SMOC1,NELL1,RHBDL3,PCDH11X,SYT4,ADGRL3,CACNA1E,PCDHGA3,SYT6,NUCB1,GRIN1,VWCE,CRB1,TLL2,REPS2,PADI2,PCDH8,PCDH9,CDH8,CDH10,TPD52,TPM4,HPCA,NRXN1,CABP1,NECAB2,FAT3,PPP3CB,PLCH2,VCAN,NCAN,MASP1,SYTL2,LRP8,CDH20,PCDH15,CALN1,CRTAC1,RET,SYT15,RASGRP2" GO: Molecular Function GO:0004970 ionotropic glutamate receptor activity 1.15E-06 1.68E-03 7.64E-05 6.01E-04 8 19 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" GO: Molecular Function GO:0015077 monovalent inorganic cation transmembrane transporter activity 1.38E-06 2.03E-03 8.82E-05 6.94E-04 40 375 "ASIC1,KCNIP2,SLC44A5,SCN3A,SCN4B,SCNN1D,ASIC4,SLC1A2,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,SNAP25,ATP1A2,ATP1A3,SCN3B,ABCC8,AZIN2,KCNK10,ASIC3,KCNT2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9,SLC6A15" GO: Molecular Function GO:0022834 ligand-gated channel activity 1.78E-06 2.61E-03 1.03E-04 8.12E-04 22 148 "ASIC1,RYR1,SCNN1D,RASA3,ABCC8,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,ASIC3,CHRNB2,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,DLG3" GO: Molecular Function GO:0015276 ligand-gated ion channel activity 1.78E-06 2.61E-03 1.03E-04 8.12E-04 22 148 "ASIC1,RYR1,SCNN1D,RASA3,ABCC8,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,ASIC3,CHRNB2,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,DLG3" GO: Molecular Function GO:0005234 extracellularly glutamate-gated ion channel activity 1.83E-06 2.68E-03 1.03E-04 8.12E-04 8 20 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" GO: Molecular Function GO:0008066 glutamate receptor activity 2.45E-06 3.60E-03 1.33E-04 1.05E-03 9 27 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" GO: Molecular Function GO:0019904 protein domain specific binding 5.45E-06 8.00E-03 2.86E-04 2.25E-03 62 729 "MAPT,ACTN2,HPCAL4,SGIP1,TACC2,NLGN1,ARHGAP5,SHANK2,SNAP25,ATP2B2,SON,ENKUR,ADAM15,NFASC,NCAM1,BCL2L2,KIRREL3,GNAS,CACNB2,TCF7L2,TCF12,HAP1,GRIA1,GRIA2,GRIK2,TGFBR3,TJP1,PAX6,ZNF384,PDE2A,ASIC3,HNRNPK,DLGAP3,CADM1,TJP2,PLXNB3,MICAL1,PRRX1,ATCAY,POU3F2,MED1,RGS6,PRKCZ,ARHGEF4,CTNND1,PROX1,ZBTB16,SIRPA,DNAJC6,PMEPA1,ELMO1,KCNJ4,KCNJ9,DLG2,DLG3,DNM2,ATN1,DTNA,L1CAM,ABI2,OLIG2,EPB41L2" GO: Molecular Function GO:0005215 transporter activity 6.31E-06 9.25E-03 3.19E-04 2.51E-03 96 1294 "TTYH1,ASIC1,KCNIP2,RYR1,FABP7,SLC44A5,TOMM40L,SCN3A,SCN4B,SCNN1D,ASIC4,SLC30A10,RASA3,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC2A5,SLC6A9,SLC8A2,SLC8A3,SLC14A1,SLCO1A2,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,FXYD6,GJB1,SLCO1C1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,CACNB2,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,TF,MFSD2A,P2RX7,KCNK10,PDE2A,BEST3,ANO5,ASIC3,CHRNB2,SLC22A6,PMP2,BEST1,SLC36A4,KCNT2,SLC45A1,TOMM20,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,SV2A,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,SLC17A6,SLC25A18,ABCC9,SLC6A15,NUP214,RLBP1,SFXN5,SLC39A12,SIDT2,CACNG7,SLC4A10" GO: Molecular Function GO:0019894 kinesin binding 1.96E-05 2.87E-02 9.57E-04 7.53E-03 10 42 "SYBU,SHTN1,CLSTN1,NEK6,KIF1B,ATCAY,MAPK8,LRP8,KCNA2,KCNC1" GO: Molecular Function GO:0022835 transmitter-gated channel activity 3.22E-05 4.73E-02 1.48E-03 1.16E-02 8 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" GO: Molecular Function GO:0022824 transmitter-gated ion channel activity 3.22E-05 4.73E-02 1.48E-03 1.16E-02 8 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" GO: Biological Process GO:0022008 neurogenesis 2.03E-36 1.33E-32 1.33E-32 1.24E-31 197 1628 "MAG,ZFYVE27,MAP6,MAPT,ACHE,MBP,CEND1,ADGRV1,EYA1,ATAT1,KCNIP2,RTN1,DSCAML1,SLITRK1,FABP7,NLGN4X,DRAXIN,AGT,DISP3,LRRC7,SEMA6A,FOXG1,SOX6,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,TACC2,NLGN1,LRRC4C,SHTN1,LRRC55,SLC8A3,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,MTR,ASTN1,SMARCE1,SNAP25,NRG3,FYN,ATP2B2,PALLD,USP33,SOX1,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,SALL3,DNER,NAP1L2,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,NEUROD1,RND1,ARHGEF7,SYT4,DCLK2,NKX2-2,SEMA4A,ROBO3,CAMSAP2,MYRF,CDK5R2,UNC5D,MMD2,CNTN2,ADGRL3,CACNA1A,GPM6A,ACSL6,VWC2,DDR1,TCF7L2,ZEB1,TCF12,HAP1,CAMK2A,CECR2,BRSK2,GRIN1,TF,OMG,OPCML,CRB1,PTPN5,AIFM1,NEURL1,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,GPR37L1,ADGRG1,HMGB1,LRTM2,CHRNB2,HNRNPK,TLX1,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,ATCAY,POU3F2,POU3F4,MED1,CRMP1,TENM4,PPP3CB,RGS6,FEZ2,FEZ1,CHD5,VCAN,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,HES5,PROX1,BRINP3,KLK6,PSD,DPYSL5,PLPPR5,TUBB2B,PTCH1,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,KCNA1,OLFM3,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,KCNJ10,PCDH15,KCNMA1,PEX5,DLG2,OLIG1,DNM2,RAP1GAP,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,USH1C,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,SLC4A10,ELAVL4,ROM1,EN2,OLIG2,RPE65,SEZ6" GO: Biological Process GO:0048699 generation of neurons 4.27E-35 2.80E-31 1.40E-31 1.31E-30 187 1528 "MAG,ZFYVE27,MAP6,MAPT,ACHE,MBP,CEND1,ADGRV1,EYA1,ATAT1,KCNIP2,RTN1,DSCAML1,SLITRK1,NLGN4X,DRAXIN,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,MTR,ASTN1,SNAP25,NRG3,FYN,ATP2B2,PALLD,USP33,SOX1,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,SALL3,DNER,NAP1L2,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,NEUROD1,RND1,SYT4,DCLK2,NKX2-2,SEMA4A,ROBO3,CAMSAP2,CDK5R2,UNC5D,MMD2,CNTN2,ADGRL3,CACNA1A,GPM6A,ACSL6,VWC2,DDR1,TCF7L2,ZEB1,TCF12,HAP1,CAMK2A,CECR2,BRSK2,GRIN1,TF,OMG,OPCML,CRB1,PTPN5,AIFM1,NEURL1,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,GPR37L1,ADGRG1,HMGB1,LRTM2,CHRNB2,HNRNPK,TLX1,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,ATCAY,POU3F2,POU3F4,MED1,CRMP1,TENM4,PPP3CB,RGS6,FEZ2,FEZ1,CHD5,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,HES5,PROX1,BRINP3,KLK6,PSD,DPYSL5,PLPPR5,TUBB2B,PTCH1,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,KCNA1,OLFM3,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,PCDH15,KCNMA1,PEX5,DLG2,OLIG1,DNM2,RAP1GAP,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,USH1C,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,SLC4A10,ELAVL4,ROM1,EN2,OLIG2,RPE65,SEZ6" GO: Biological Process GO:0030182 neuron differentiation 6.56E-33 4.30E-29 1.43E-29 1.34E-28 173 1398 "MAG,ZFYVE27,MAP6,MAPT,ACHE,MBP,CEND1,ADGRV1,EYA1,ATAT1,KCNIP2,RTN1,DSCAML1,SLITRK1,NLGN4X,DRAXIN,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,CCDC88A,ASCL1,SLIT1,CAPRIN2,BRINP2,MTR,SNAP25,FYN,ATP2B2,PALLD,USP33,SOX1,TNIK,SOX5,NKX6-2,SALL3,NAP1L2,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,NEUROD1,RND1,SYT4,DCLK2,NKX2-2,SEMA4A,ROBO3,CAMSAP2,UNC5D,MMD2,CNTN2,CACNA1A,GPM6A,ACSL6,VWC2,DDR1,ZEB1,TCF12,HAP1,CAMK2A,CECR2,BRSK2,GRIN1,OMG,OPCML,CRB1,PTPN5,AIFM1,NEURL1,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,GPR37L1,HMGB1,LRTM2,CHRNB2,HNRNPK,TLX1,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,ATCAY,POU3F2,POU3F4,MED1,CRMP1,TENM4,PPP3CB,RGS6,FEZ2,FEZ1,CHD5,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,HES5,PROX1,BRINP3,KLK6,PSD,DPYSL5,PLPPR5,PTCH1,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,OLFM3,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,PCDH15,KCNMA1,PEX5,DLG2,OLIG1,DNM2,RAP1GAP,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,USH1C,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,SLC4A10,ELAVL4,ROM1,EN2,OLIG2,RPE65,SEZ6" GO: Biological Process GO:0099536 synaptic signaling 1.55E-29 1.02E-25 1.91E-26 1.79E-25 109 687 "ABAT,ASIC1,MAPT,ACHE,MBP,SYT9,RTN3,KCNIP2,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,AMPH,CNIH2,PPFIA1,APBA2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A6,RPH3A,SLC6A9,SLC8A2,SLC8A3,SHANK2,CADPS,CSPG5,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP2B2,GABBR1,GAD2,JPH4,KIF1B,CPLX2,NCAM1,GFAP,NCDN,GLS,SYT4,CNTN2,CACNA1A,GPM6B,CACNA1E,CACNB2,NRGN,HAP1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,P2RX7,NEURL1,TNR,PCDH8,CDH8,PTGDR2,HRH3,LGI1,PDYN,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCG,PRKCZ,CTNND2,RIMS3,SYTL2,CNIH3,LRP8,BLOC1S6,KCNA1,PTPRD,SV2A,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,RASGRF1,DTNA,RGS10,SYT15,CACNG7,SEZ6" GO: Biological Process GO:0098916 anterograde trans-synaptic signaling 2.04E-29 1.34E-25 1.91E-26 1.79E-25 108 678 "ABAT,ASIC1,MAPT,ACHE,MBP,SYT9,RTN3,KCNIP2,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,AMPH,CNIH2,PPFIA1,APBA2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A6,RPH3A,SLC6A9,SLC8A2,SLC8A3,SHANK2,CADPS,CSPG5,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP2B2,GABBR1,GAD2,JPH4,KIF1B,CPLX2,NCAM1,GFAP,NCDN,GLS,SYT4,CNTN2,CACNA1A,GPM6B,CACNA1E,CACNB2,NRGN,HAP1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,P2RX7,NEURL1,TNR,PCDH8,CDH8,PTGDR2,HRH3,LGI1,PDYN,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCG,PRKCZ,CTNND2,RIMS3,SYTL2,CNIH3,LRP8,BLOC1S6,KCNA1,PTPRD,SV2A,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,RASGRF1,DTNA,SYT15,CACNG7,SEZ6" GO: Biological Process GO:0007268 chemical synaptic transmission 2.04E-29 1.34E-25 1.91E-26 1.79E-25 108 678 "ABAT,ASIC1,MAPT,ACHE,MBP,SYT9,RTN3,KCNIP2,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,AMPH,CNIH2,PPFIA1,APBA2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A6,RPH3A,SLC6A9,SLC8A2,SLC8A3,SHANK2,CADPS,CSPG5,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP2B2,GABBR1,GAD2,JPH4,KIF1B,CPLX2,NCAM1,GFAP,NCDN,GLS,SYT4,CNTN2,CACNA1A,GPM6B,CACNA1E,CACNB2,NRGN,HAP1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,P2RX7,NEURL1,TNR,PCDH8,CDH8,PTGDR2,HRH3,LGI1,PDYN,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCG,PRKCZ,CTNND2,RIMS3,SYTL2,CNIH3,LRP8,BLOC1S6,KCNA1,PTPRD,SV2A,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,RASGRF1,DTNA,SYT15,CACNG7,SEZ6" GO: Biological Process GO:0099537 trans-synaptic signaling 2.04E-29 1.34E-25 1.91E-26 1.79E-25 108 678 "ABAT,ASIC1,MAPT,ACHE,MBP,SYT9,RTN3,KCNIP2,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,AMPH,CNIH2,PPFIA1,APBA2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A6,RPH3A,SLC6A9,SLC8A2,SLC8A3,SHANK2,CADPS,CSPG5,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP2B2,GABBR1,GAD2,JPH4,KIF1B,CPLX2,NCAM1,GFAP,NCDN,GLS,SYT4,CNTN2,CACNA1A,GPM6B,CACNA1E,CACNB2,NRGN,HAP1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,P2RX7,NEURL1,TNR,PCDH8,CDH8,PTGDR2,HRH3,LGI1,PDYN,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCG,PRKCZ,CTNND2,RIMS3,SYTL2,CNIH3,LRP8,BLOC1S6,KCNA1,PTPRD,SV2A,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,RASGRF1,DTNA,SYT15,CACNG7,SEZ6" GO: Biological Process GO:0048666 neuron development 1.32E-27 8.68E-24 1.09E-24 1.02E-23 141 1114 "MAG,ZFYVE27,MAP6,MAPT,ACHE,MBP,ADGRV1,ATAT1,KCNIP2,DSCAML1,SLITRK1,DRAXIN,LRRC7,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,CCDC88A,ASCL1,SLIT1,CAPRIN2,MTR,SNAP25,FYN,ATP2B2,PALLD,USP33,SOX1,TNIK,SALL3,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,NEUROD1,RND1,SYT4,DCLK2,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,CACNA1A,GPM6A,ACSL6,DDR1,HAP1,CAMK2A,CECR2,BRSK2,GRIN1,OMG,OPCML,CRB1,PTPN5,NEURL1,PAX6,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,HMGB1,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,ATCAY,POU3F2,CRMP1,TENM4,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,HES5,KLK6,DPYSL5,PLPPR5,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,OLFM3,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,PCDH15,DLG2,DNM2,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,USH1C,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,SLC4A10,ELAVL4,EN2,RPE65,SEZ6" GO: Biological Process GO:0051960 regulation of nervous system development 2.79E-26 1.83E-22 2.03E-23 1.90E-22 120 881 "MAG,MAPT,ACHE,MBP,SYNDIG1,CEND1,EYA1,SLITRK1,RXRG,DRAXIN,LRRTM4,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,APBB1,SLITRK3,NLGN1,LRRC4C,SHTN1,CLSTN1,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,SNAP25,NRG3,FYN,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,ADGRB2,NAP1L2,RAP1GAP2,SPART,CLASP2,GFAP,NEUROD1,SYT4,NKX2-2,SEMA4A,MYRF,UNC5D,MMD2,CNTN2,ADGRL3,CACNA1A,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,GRIN1,TF,OMG,PTPN5,NEURL1,PAX6,TNR,ZMYND8,GPR37L1,ADGRG1,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,POU3F2,MED1,CRMP1,TENM4,RGS6,FEZ1,RBPJ,PRKACB,DOCK7,HES5,PROX1,BRINP3,KLK6,PLPPR5,LRRTM3,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,RFX4,VANGL2,SLC39A12,EFNA3,CBLN2,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0007267 cell-cell signaling 1.12E-23 7.37E-20 7.37E-21 6.90E-20 142 1233 "ABAT,ASIC1,MAPT,ACHE,MBP,SYT9,LGR4,RTN3,WLS,KCNIP2,ADORA1,ADORA3,NLGN4X,AGT,SCN4B,PLA2G6,FGF14,AMPH,ANK2,CNIH2,PPFIA1,PKP4,APBA2,BCAN,SYBU,NLGN1,CLSTN1,SLC1A2,SLC1A6,RPH3A,MADD,SLC6A9,SLC8A2,SLC8A3,SHANK2,CADPS,PDE8B,CSPG5,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP2B2,GABBR1,SCN3B,ILDR2,GAD2,JPH4,KIF1B,CPLX2,NCAM1,GFAP,NCDN,FGF17,GJB1,NEUROD1,ARHGEF7,ABCC8,GLS,SYT4,GNAS,NODAL,CNTN2,CACNA1A,GPM6B,CACNA1E,CACNB2,TCF7L2,NRGN,HAP1,CAMK2A,CAMK2G,SYT6,BRSK2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,CRB1,PTPN5,P2RX7,TJP1,NEURL1,PAX6,CDC42,TNR,PCDH8,CDH8,PTGDR2,HRH3,LGI1,PDE1C,PDE3B,PDYN,ZMYND8,ADGRG1,CHRM1,CHRM4,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCG,PRKCZ,CTNND2,ECE2,RIMS3,SYTL2,PTHLH,CNIH3,LRP8,BLOC1S6,KCNA1,PTPRD,SV2A,KCNJ10,KCNJ11,KCNMA1,KCNQ2,DLG2,DLG3,RASGRF1,DTNA,RGS10,SYT15,SIDT2,CACNG7,EFNA3,SEZ6" GO: Biological Process GO:0031175 neuron projection development 9.41E-23 6.17E-19 5.61E-20 5.26E-19 119 953 "MAG,ZFYVE27,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,LRRC7,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,CCDC88A,SLIT1,CAPRIN2,MTR,SNAP25,FYN,PALLD,USP33,TNIK,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,SYT4,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,CACNA1A,GPM6A,ACSL6,DDR1,HAP1,CAMK2A,BRSK2,GRIN1,OMG,PTPN5,NEURL1,PAX6,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,HMGB1,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,ATCAY,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,KLK6,DPYSL5,PLPPR5,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,DNM2,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,ELAVL4,SEZ6" GO: Biological Process GO:0050804 modulation of chemical synaptic transmission 4.04E-21 2.65E-17 2.21E-18 2.07E-17 65 357 "ABAT,ASIC1,MAPT,ACHE,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,CNIH2,BCAN,NLGN1,CLSTN1,SLC8A2,SLC8A3,SHANK2,CSPG5,SORCS3,IGSF9B,SNAP25,ATP1A2,ATP2B2,GABBR1,JPH4,CPLX2,NCAM1,GFAP,NCDN,CNTN2,CACNA1A,GPM6B,NRGN,HAP1,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,NEURL1,TNR,LGI1,ZMYND8,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCZ,CTNND2,RIMS3,CNIH3,LRP8,KCNJ10,RASGRF1,CACNG7" GO: Biological Process GO:0050767 regulation of neurogenesis 7.32E-21 4.80E-17 3.69E-18 3.46E-17 102 784 "MAG,MAPT,ACHE,MBP,EYA1,DRAXIN,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,APBB1,NLGN1,LRRC4C,SHTN1,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,SNAP25,NRG3,FYN,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,NAP1L2,RAP1GAP2,SPART,CLASP2,GFAP,NEUROD1,SYT4,NKX2-2,SEMA4A,UNC5D,MMD2,CNTN2,CACNA1A,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,GRIN1,TF,OMG,PTPN5,NEURL1,PAX6,TNR,ZMYND8,GPR37L1,ADGRG1,CHRNB2,HNRNPK,NLGN3,SERPINE2,SEMA5B,NEGR1,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,POU3F2,MED1,CRMP1,TENM4,RGS6,FEZ1,RBPJ,DOCK7,HES5,PROX1,BRINP3,KLK6,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,SLC39A12,EFNA3,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0007417 central nervous system development 1.90E-20 1.25E-16 8.89E-18 8.33E-17 118 1002 "MAG,ABAT,MAPT,MBP,CEND1,ATAT1,ARID1A,WLS,NDRG2,DSCAML1,FABP7,NLGN4X,DRAXIN,AGT,ACTL6B,HPCAL4,FOXG1,MOG,SOX6,SH3GL2,BCAN,TACC2,SLC1A2,RPH3A,SLC8A3,MT3,ASCL1,SLIT1,TAGLN3,DLL3,ATM,NRG3,FYN,ATP2B2,SOX1,SOX5,SOX10,NKX6-2,SALL3,GART,DNER,NCAM1,GFAP,KIRREL3,NEUROD1,NHLH1,SYT4,DCLK2,NKX2-2,NODAL,MYRF,CDK5R2,UNC5D,CNTN2,CACNA1A,TCF7L2,ZEB1,NRGN,HAP1,PTBP2,GRIN1,OMG,INA,NEURL1,PAX6,CDC42,TNR,PADI2,PCDH9,DCLK1,RBFOX2,SEZ6L,GPR37L1,HAPLN2,ADGRG1,PFKFB3,CHRNB2,HNRNPK,TLX1,HPCA,NLGN3,SERPINE2,NRXN1,CNTN1,POU3F2,POU3F4,MED1,TENM4,CHD5,VCAN,NCAN,RBPJ,DOCK7,CTNND1,HES5,ECE2,PROX1,KLK6,ZBTB16,PTCH1,CA10,LRP8,KCNA1,KCNC1,PTPRZ1,KCNJ10,ARNT2,NAV2,PEX5,OLIG1,ATN1,RTN4,CRTAC1,RFX4,SLC4A10,EN2,OLIG2,SEZ6" GO: Biological Process GO:0045664 regulation of neuron differentiation 4.65E-20 3.05E-16 2.03E-17 1.90E-16 90 655 "MAG,MAPT,ACHE,MBP,EYA1,DRAXIN,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,APBB1,NLGN1,LRRC4C,SHTN1,MT3,CCDC88A,ASCL1,SLIT1,CAPRIN2,BRINP2,SNAP25,FYN,TNIK,SOX5,NAP1L2,RAP1GAP2,SPART,CLASP2,GFAP,NEUROD1,SYT4,NKX2-2,SEMA4A,MMD2,CNTN2,CACNA1A,ACSL6,VWC2,ZEB1,TCF12,HAP1,GRIN1,OMG,PTPN5,NEURL1,PAX6,TNR,ZMYND8,GPR37L1,CHRNB2,HNRNPK,NLGN3,SERPINE2,SEMA5B,NEGR1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,POU3F2,MED1,CRMP1,RGS6,FEZ1,RBPJ,HES5,PROX1,BRINP3,KLK6,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,SLC39A12,EFNA3,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0050803 regulation of synapse structure or activity 8.84E-19 5.79E-15 3.62E-16 3.39E-15 53 272 "MAPT,SYNDIG1,SLITRK1,ADORA1,AGT,LRRTM4,FGF14,SLITRK3,BCAN,NLGN1,CLSTN1,SLC8A2,SLC8A3,SHANK2,SLIT1,SORCS3,SNAP25,ATP2B2,JPH4,CPLX2,ADGRB2,NCAM1,GFAP,NCDN,CNTN2,ADGRL3,NRGN,CAMK2A,GRIA1,GRIK2,GRIN1,SHISA7,PTPN5,NEURL1,CDC42,TNR,ZMYND8,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,FLRT1,PPP3CB,NCAN,PRKCZ,CTNND2,LRRTM3,MAGI2,KCNJ10,RASGRF1,CBLN2" GO: Biological Process GO:0048812 neuron projection morphogenesis 5.89E-18 3.86E-14 2.27E-15 2.13E-14 84 630 "MAG,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,USP33,TNIK,SPART,NFASC,NCAM1,CLASP2,KIRREL3,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,GPM6A,DDR1,CAMK2A,BRSK2,GRIN1,OMG,PAX6,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,HNRNPK,NLGN3,NRXN1,SEMA5B,FLRT1,PLXNB3,PACSIN1,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,PRKCZ,CTNND2,MAPK8,DPYSL5,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,ATL1,VANGL2,EFNA3,ELAVL4" GO: Biological Process GO:0030030 cell projection organization 4.01E-17 2.63E-13 1.46E-14 1.37E-13 140 1423 "MAG,TTYH1,ZFYVE27,MAP6,MAPT,ACHE,MBP,ACTN2,ADGRV1,DSCAML1,SLITRK1,ERMN,TUBB4A,DRAXIN,LRRC7,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,CCDC88A,SLIT1,CAPRIN2,MTR,SNAP25,FYN,ATP2B2,PALLD,USP33,TNIK,RAP1GAP2,SPART,NFASC,NCAM1,CLASP2,GFAP,GFRA1,NCDN,KIRREL3,ARHGEF7,SYT4,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,CACNA1A,GPM6A,ACSL6,DDR1,HAP1,CAMK2A,CECR2,BRSK2,GRIN1,OMG,PTPN5,P2RX7,NEURL1,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,ZMYND8,HMGB1,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,FLRT1,VAV2,PLXNB3,CNTN1,PRRX1,SPATA6,P2RY12,PACSIN1,FAT3,ATCAY,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,PRKCZ,ARHGEF4,CTNND2,MAPK8,HES5,KLK6,DPYSL5,PLPPR5,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,PTPRD,PLPPR4,PTPRO,PTPRZ1,NTM,PCDH15,DNAH9,DNM2,RAP1GAP,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RET,USH1C,RFX4,ATL1,VANGL2,SLC39A12,EFNA3,ABI2,ELAVL4,PLEKHO1,SEZ6" GO: Biological Process GO:0060284 regulation of cell development 6.29E-17 4.12E-13 2.17E-14 2.03E-13 109 985 "MAG,MAPT,ACHE,MBP,EYA1,DRAXIN,DISP3,LRRC7,SEMA6A,FOXG1,SEMA6C,PI16,APBB1,NLGN1,LRRC4C,SHTN1,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,SNAP25,NRG3,FYN,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,NAP1L2,RAP1GAP2,SPART,CLASP2,GFAP,PHLDB1,NEUROD1,ARHGEF7,SYT4,NKX2-2,SEMA4A,NODAL,UNC5D,MMD2,CNTN2,CACNA1A,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,GRIN1,TF,OMG,PTPN5,TGFBR3,NEURL1,PAX6,CDC42,TNR,ZMYND8,GPR37L1,ADGRG1,CHRNB2,HNRNPK,NLGN3,SERPINE2,SEMA5B,NEGR1,TJP2,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,POU3F2,MED1,CRMP1,TENM4,RGS6,FEZ1,RBPJ,DOCK7,HES5,PROX1,BRINP3,KLK6,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,SLC39A12,EFNA3,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0048667 cell morphogenesis involved in neuron differentiation 5.19E-16 3.40E-12 1.70E-13 1.59E-12 77 590 "MAG,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,ATP2B2,USP33,TNIK,SPART,NFASC,NCAM1,CLASP2,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,CAMK2A,BRSK2,GRIN1,OMG,PAX6,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,NLGN3,NRXN1,SEMA5B,PLXNB3,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,CTNND2,MAPK8,DPYSL5,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,ATL1,VANGL2,EFNA3,ELAVL4" GO: Biological Process GO:0007610 behavior 8.38E-16 5.50E-12 2.62E-13 2.45E-12 83 671 "EPS8,ABAT,ASIC1,MAPT,CEND1,SLITRK1,ADORA1,NLGN4X,AGT,PLA2G6,FGF14,UNC79,AMPH,ANXA7,APBA2,APBB1,NLGN1,SLC1A2,SLC8A2,SLC8A3,SHANK2,PDE8B,SORCS3,ASTN1,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,JPH4,NPAS3,NCAM1,KIRREL3,GLS,DDHD2,CNTN2,ADGRL3,CACNA1A,CACNA1E,PRLHR,NRGN,GRIA1,GRID1,GRIK2,GRIN1,GPR88,CCKBR,PTPN5,USP2,KCNK10,TNR,HRH3,SEZ6L,PIRT,CIART,CHRNB2,NLGN3,SERPINE2,NRXN1,NRXN2,NEGR1,PPP3CB,PRKCG,PRKCZ,CTNND2,MAPK10,PUM1,KCNA2,PTPRZ1,KCNJ10,KCNK2,PCDH15,KCNMA1,NAV2,DSCAM,RASGRF1,PAK5,ABI2,FGFBP3,SLC4A10,ELAVL4,RCAN2,SEZ6" GO: Biological Process GO:0010975 regulation of neuron projection development 1.65E-15 1.08E-11 4.91E-13 4.60E-12 68 492 "MAG,MAPT,ACHE,MBP,DRAXIN,LRRC7,SEMA6A,SEMA6C,APBB1,NLGN1,LRRC4C,SHTN1,MT3,CCDC88A,SLIT1,CAPRIN2,SNAP25,FYN,TNIK,RAP1GAP2,SPART,CLASP2,GFAP,SYT4,SEMA4A,CNTN2,CACNA1A,ACSL6,HAP1,GRIN1,OMG,PTPN5,NEURL1,PAX6,TNR,ZMYND8,CHRNB2,HNRNPK,NLGN3,SERPINE2,SEMA5B,NEGR1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,POU3F2,CRMP1,FEZ1,RBPJ,KLK6,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,DSCAM,RTN4,L1CAM,RET,SLC39A12,ELAVL4,SEZ6" GO: Biological Process GO:0051962 positive regulation of nervous system development 2.18E-15 1.43E-11 6.20E-13 5.81E-12 71 531 "MAG,MAPT,ACHE,SYNDIG1,SLITRK1,LRRTM4,LRRC7,SEMA6A,FOXG1,APBB1,SLITRK3,NLGN1,SHTN1,CLSTN1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SOX10,NKX6-2,ADGRB2,NAP1L2,GFAP,NEUROD1,SYT4,NKX2-2,MYRF,MMD2,ADGRL3,ACSL6,VWC2,ZEB1,TCF12,HAP1,TF,PTPN5,NEURL1,PAX6,ZMYND8,GPR37L1,LRTM2,HNRNPK,NLGN3,SERPINE2,NRXN1,NEGR1,FLRT1,PLXNB3,CNTN1,PACSIN1,TENM4,RGS6,FEZ1,PROX1,BRINP3,PLPPR5,LRRTM3,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DSCAM,RTN4,L1CAM,RET,CBLN2,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0042391 regulation of membrane potential 2.50E-15 1.64E-11 6.82E-13 6.39E-12 59 391 "ABAT,ASIC1,ACTN2,KCNIP2,ADORA1,NLGN4X,AGT,SCN3A,SCN4B,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,SHTN1,SLC1A6,IGSF9B,ATP1A2,ATP1A3,SCN3B,SPART,STOX1,POPDC3,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIK2,GRIK3,GRIN1,GPR88,P2RX7,KCNK10,ZMYND8,NTSR2,CHRNB2,NLGN3,NRXN1,SLC25A27,RIMS4,PRKCZ,NOS1AP,RIMS3,CNIH3,KCNA1,KCNA2,KCND3,KCNH1,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,PID1,DPP6,SEZ6" GO: Biological Process GO:0007420 brain development 3.94E-15 2.59E-11 1.03E-12 9.69E-12 88 755 "MAG,ABAT,MAPT,MBP,CEND1,ATAT1,ARID1A,WLS,NDRG2,DSCAML1,FABP7,NLGN4X,DRAXIN,FOXG1,BCAN,TACC2,SLC1A2,RPH3A,SLC8A3,MT3,ASCL1,SLIT1,ATM,NRG3,FYN,ATP2B2,SOX1,SALL3,GART,NCAM1,KIRREL3,NEUROD1,SYT4,DCLK2,NKX2-2,NODAL,CDK5R2,CNTN2,CACNA1A,TCF7L2,NRGN,HAP1,PTBP2,GRIN1,INA,NEURL1,PAX6,CDC42,TNR,PADI2,PCDH9,DCLK1,RBFOX2,SEZ6L,GPR37L1,ADGRG1,PFKFB3,CHRNB2,HNRNPK,HPCA,SERPINE2,NRXN1,CNTN1,POU3F2,POU3F4,MED1,CHD5,RBPJ,DOCK7,CTNND1,HES5,ECE2,PROX1,PTCH1,CA10,LRP8,KCNA1,KCNC1,PTPRZ1,ARNT2,PEX5,RTN4,CRTAC1,RFX4,SLC4A10,EN2,OLIG2,SEZ6" GO: Biological Process GO:0050808 synapse organization 6.17E-15 4.05E-11 1.56E-12 1.46E-11 46 258 "ACHE,SYNDIG1,SLITRK1,NLGN4X,LRRTM4,ANK3,SLITRK3,NLGN1,CLSTN1,SHANK2,SLIT1,SNCB,ATP2B2,ADGRB2,DNER,NFASC,KIRREL3,NFIA,CNTN2,ADGRL3,CACNA1A,GPM6A,CACNB2,NRDC,GRIN1,NEURL1,CDC42,TNR,SEZ6L,ZMYND8,LRTM2,CHRNB2,HNRNPK,NLGN3,CADM1,NRXN1,NRXN2,FLRT1,NCAN,CTNND2,LRRTM3,MAGI2,PTPRD,DSCAM,CBLN2,SEZ6" GO: Biological Process GO:0034220 ion transmembrane transport 3.41E-14 2.23E-10 8.28E-12 7.75E-11 108 1064 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,RYR1,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,UNC79,SLC30A10,ANK2,ANK3,RASA3,CNIH2,NLGN1,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC6A9,SLC8A2,SLC8A3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,CAB39,AHCYL1,JPH4,FXYD6,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,P2RX7,KCNK10,PDE2A,PDE4B,PIRT,BEST3,ANO5,ASIC3,CHRNB2,SLC22A6,NLGN3,NRXN1,BEST1,P2RY12,SLC36A4,KCNT2,PRKAB2,NOS1AP,PTAFR,ITGAV,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,DNM2,SLC17A6,DPP6,RASGRF1,ABCC9,SLC6A15,SFXN5,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0051049 regulation of transport 3.57E-14 2.34E-10 8.35E-12 7.82E-11 167 1975 "TTYH1,ABAT,ASIC1,MAPT,ACHE,APC2,SYT9,LGR4,ACTN2,WLS,KCNIP2,ADCYAP1R1,ADORA1,ADORA3,FCGR1A,AGT,SCN3A,SCN4B,DISP3,PLA2G6,FGF14,FGR,FHL1,ELMOD1,SGIP1,ANK2,ANK3,CNIH2,SH3GL2,APBB1,GPAM,SORBS1,SYBU,NLGN1,SLC1A2,RPH3A,MADD,CADPS,PDE8B,LGI3,ARFGAP1,ASPH,SLN,SNAP25,ATP1A2,ATP2B2,GABBR1,SCN3B,MYBPC1,CAB39,AHCYL1,JPH4,CPLX2,NCAM1,CLASP2,GFAP,NEUROD1,MLC1,ARHGEF7,ABCC8,OS9,SYT4,GNAS,NODAL,CDK5R2,WWC1,CACNA1A,GPM6B,ACSL6,CACNA1E,NPPA,CACNB2,TCF7L2,CLEC9A,GPR26,HAP1,AZIN2,CAMK2A,CAMK2G,SYT6,NUCB1,BRSK2,GRIN1,ATP13A2,TF,CCKBR,SPX,PTPN5,P2RX7,KCNK10,PAX6,CDC42,HRH3,ZNF384,PDE1C,PDE2A,PDE3B,PDE4B,PIRT,BEST3,HMGB1,CHGA,CHRM1,TUB,CHRNB2,HNRNPK,HPCA,NLGN3,SERPINE2,CADM1,NRXN1,CNTN1,CABP1,SLC25A27,BEST1,P2RY12,PACSIN1,MED1,PNKD,SNCAIP,PPP3CB,NKAIN4,RIMS4,CALY,PRKCG,PRKCZ,MAPK8,NOS1AP,RIMS3,SYTL2,SIRPA,PTAFR,PTCH1,DNAJC6,ITGAV,CNIH3,MAGI2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,RABGAP1L,KCNJ10,KCNJ11,KCNMA1,KCNN3,KCNQ2,NKAIN1,RAB5B,PID1,DNM2,DPP6,C12orf4,RAP1GAP,GOPC,RASGRF1,RTN4,NUP214,SYT15,SIDT2,CACNG7,SH3GLB1" GO: Biological Process GO:0060322 head development 5.01E-14 3.29E-10 1.13E-11 1.06E-10 89 802 "MAG,ABAT,MAPT,MBP,CEND1,ATAT1,ARID1A,WLS,NDRG2,DSCAML1,FABP7,NLGN4X,DRAXIN,FOXG1,BCAN,TACC2,SLC1A2,RPH3A,SLC8A3,MT3,ASCL1,SLIT1,ASPH,ATM,NRG3,FYN,ATP2B2,SOX1,SALL3,GART,NCAM1,KIRREL3,NEUROD1,SYT4,DCLK2,NKX2-2,NODAL,CDK5R2,CNTN2,CACNA1A,TCF7L2,NRGN,HAP1,PTBP2,GRIN1,INA,NEURL1,PAX6,CDC42,TNR,PADI2,PCDH9,DCLK1,RBFOX2,SEZ6L,GPR37L1,ADGRG1,PFKFB3,CHRNB2,HNRNPK,HPCA,SERPINE2,NRXN1,CNTN1,POU3F2,POU3F4,MED1,CHD5,RBPJ,DOCK7,CTNND1,HES5,ECE2,PROX1,PTCH1,CA10,LRP8,KCNA1,KCNC1,PTPRZ1,ARNT2,PEX5,RTN4,CRTAC1,RFX4,SLC4A10,EN2,OLIG2,SEZ6" GO: Biological Process GO:0006811 ion transport 9.03E-14 5.92E-10 1.97E-11 1.85E-10 144 1627 "TTYH1,ABAT,ASIC1,ACTN2,KCNIP2,SLC25A25,ADCYAP1R1,RYR1,ADORA1,ADORA3,SLC44A5,TOMM40L,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,UNC79,SLC30A10,ANK1,ANK2,ANK3,RASA3,CNIH2,PPFIA1,CACHD1,NLGN1,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC1A7,LRRC55,SLC6A9,SLC8A2,SLC8A3,MT3,SLCO1A2,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SCN3B,CAB39,AHCYL1,JPH4,STARD10,FXYD6,SLCO1C1,MLC1,ABCC8,GLS,GNAS,ANO4,CACNA1A,GPM6A,GPM6B,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,AZIN2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,TF,CCKBR,SPX,MFSD2A,P2RX7,KCNK10,HRH3,PDE2A,PDE4B,PIRT,BEST3,CA14,ANO5,ASIC3,CHRM1,CHRNB2,SLC22A6,NLGN3,SERPINE2,NRXN1,CNTN1,SLC25A27,BEST1,P2RY12,SLC36A4,CP,NKAIN4,KCNT2,PRKAB2,NOS1AP,PTAFR,ITGAV,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,NKAIN1,DNM2,SLC17A6,DPP6,RASGRF1,RTN4,ABCC9,SLC6A15,SFXN5,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0000904 cell morphogenesis involved in differentiation 1.05E-13 6.91E-10 2.23E-11 2.09E-10 91 840 "MAG,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,ATP2B2,PALLD,USP33,TNIK,ADAM15,SPART,NFASC,NCAM1,CLASP2,PHLDB1,ARHGEF7,SEMA4A,ROBO3,NODAL,UNC5D,CNTN2,CACNA1A,TCF7L2,CAMK2A,BRSK2,GRIN1,OMG,TGFBR3,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,NLGN3,NRXN1,SEMA5B,PLXNB3,FAT3,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,CTNND2,MAPK8,PROX1,DPYSL5,ITGAV,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,JMJD1C,ATL1,VANGL2,EFNA3,ELAVL4,TMEM100" GO: Biological Process GO:0048167 regulation of synaptic plasticity 1.16E-13 7.58E-10 2.37E-11 2.22E-10 35 169 "MAPT,ADORA1,AGT,FGF14,BCAN,NLGN1,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,ATP2B2,JPH4,CPLX2,NCAM1,GFAP,NCDN,CNTN2,NRGN,CAMK2A,GRIA1,GRIK2,GRIN1,SHISA7,PTPN5,NEURL1,TNR,HNRNPK,NLGN3,SERPINE2,PPP3CB,PRKCZ,CTNND2,KCNJ10,RASGRF1" GO: Biological Process GO:0007409 axonogenesis 1.29E-13 8.43E-10 2.55E-11 2.39E-10 63 475 "MAG,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,SLITRK3,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,FYN,USP33,SPART,NFASC,NCAM1,CLASP2,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,BRSK2,GRIN1,OMG,PAX6,TNR,DCLK1,LGI1,LRTM2,CHRNB2,NLGN3,NRXN1,SEMA5B,PLXNB3,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,DPYSL5,RGMA,PLPPR4,PTPRO,PTPRZ1,DNM2,DSCAM,RTN4,L1CAM,RET,ATL1,VANGL2,EFNA3" GO: Biological Process GO:0061564 axon development 1.54E-13 1.01E-09 2.97E-11 2.78E-10 66 514 "MAG,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,SLITRK3,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,MTR,FYN,USP33,SPART,NFASC,NCAM1,CLASP2,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,DDR1,BRSK2,GRIN1,OMG,PAX6,TNR,DCLK1,LGI1,LRTM2,CHRNB2,NLGN3,NRXN1,SEMA5B,PLXNB3,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,DPYSL5,RGMA,PLPPR4,PTPRO,PTPRZ1,DNM2,DSCAM,RTN4,L1CAM,CRTAC1,RET,ATL1,VANGL2,EFNA3" GO: Biological Process GO:0031344 regulation of cell projection organization 1.75E-13 1.15E-09 3.28E-11 3.07E-10 77 657 "MAG,MAPT,ACHE,MBP,ERMN,DRAXIN,LRRC7,SEMA6A,SEMA6C,APBB1,APC,NLGN1,LRRC4C,SHTN1,MT3,CCDC88A,SLIT1,CAPRIN2,SNAP25,FYN,TNIK,RAP1GAP2,SPART,CLASP2,GFAP,ARHGEF7,SYT4,SEMA4A,CNTN2,CACNA1A,GPM6A,ACSL6,HAP1,GRIN1,OMG,PTPN5,P2RX7,NEURL1,PAX6,CDC42,TNR,ZMYND8,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,PLXNB3,CNTN1,PRRX1,PACSIN1,FAT3,POU3F2,CRMP1,FEZ1,RBPJ,KLK6,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRO,PTPRZ1,NTM,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,USH1C,SLC39A12,ELAVL4,SEZ6" GO: Biological Process GO:2000026 regulation of multicellular organismal development 6.11E-13 4.01E-09 1.11E-10 1.04E-09 158 1893 "MAG,MAPT,ACHE,MBP,LGR4,SYNDIG1,CEND1,EYA1,F3,SLITRK1,RXRG,DRAXIN,AGT,LRRTM4,KIAA1109,DISP3,FGF1,LRRC7,SEMA6A,FOXG1,SOX6,SEMA6C,PI16,APBB1,APC,SLITRK3,NLGN1,LRRC4C,SHTN1,CLSTN1,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,SNAP25,NRG3,FYN,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,ADGRB2,NAP1L2,RAP1GAP2,SPART,NCAM1,CLASP2,STOX1,GFAP,NELL1,PHLDB1,NEUROD1,C1QC,SYT4,NKX2-2,SEMA4A,GNAS,NODAL,MYRF,UNC5D,MMD2,CNTN2,ADGRL3,CACNA1A,GPM6B,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,DDR2,GRIN1,TF,OMG,PTPN5,TGFBR3,USP2,P2RX7,TIE1,TLL2,NEURL1,PAX6,CDC42,TNR,RBFOX2,PDE3B,ZMYND8,GPR37L1,ADGRG1,HMGB1,LRTM2,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,SEMA5B,NEGR1,TJP2,FLRT1,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,NSD2,FAT3,POU3F2,MED1,CRMP1,TENM4,RGS6,CSF3R,FEZ1,RBPJ,PRKACB,DOCK7,PRKCZ,MAPK8,HES5,PROX1,BRINP3,KLK6,ZBTB16,PLPPR5,LRRTM3,PSMD13,PTCH1,PTHLH,LRP8,RGMA,MAGI2,PTPRD,PARD6A,PTPRO,PTPRZ1,NTM,KCNK2,DNM2,RAP1GAP,DSCAM,RTN4,L1CAM,RET,RFX4,VANGL2,SLC39A12,EFNA3,CBLN2,ELAVL4,OLIG2,TMEM100,SEZ6" GO: Biological Process GO:0055085 transmembrane transport 6.83E-13 4.48E-09 1.21E-10 1.13E-09 124 1356 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,RYR1,ADD3,SLC44A5,TOMM40L,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,UNC79,SLC30A10,ANK2,ANK3,RASA3,CNIH2,NLGN1,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC2A5,SLC6A9,SLC8A2,SLC8A3,SLC14A1,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,CAB39,AHCYL1,JPH4,FXYD6,GJB1,MLC1,ABCC8,ANO4,CACNA1A,GPM6A,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,ATP13A2,MFSD2A,P2RX7,KCNK10,PDE2A,PDE4B,PIRT,BEST3,ANO5,ASIC3,CHRNB2,SLC22A6,NLGN3,NRXN1,BEST1,P2RY12,SLC36A4,MFSD4A,KCNT2,PRKAB2,SLC45A1,NOS1AP,TOMM20,PTAFR,ITGAV,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,SV2A,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,PEX5,KCNQ2,DLG3,SLC25A48,DNM2,SLC17A6,DPP6,SLC25A41,SLC25A18,RASGRF1,ABCC9,SLC6A15,SFXN5,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0035637 multicellular organismal signaling 2.65E-12 1.74E-08 4.57E-10 4.28E-09 36 197 "KCNIP2,RYR1,AGT,SCN3A,SCN4B,ANK2,ANK3,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,FXYD6,NFASC,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIK2,GPR88,TNR,KCNA1,KCNA2,KCND3,KCNJ4,KCNJ11,KCNK1,KCNMA1,KCNQ2,DPP6,ABCC9,CACNG7" GO: Biological Process GO:0071805 potassium ion transmembrane transport 4.81E-12 3.15E-08 7.89E-10 7.39E-09 34 181 "ACTN2,KCNIP2,FHL1,ANK2,ANK3,SNAP25,ATP1A2,ATP1A3,CAB39,ABCC8,NPPA,KCNK10,P2RY12,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9" GO: Biological Process GO:0071804 cellular potassium ion transport 4.81E-12 3.15E-08 7.89E-10 7.39E-09 34 181 "ACTN2,KCNIP2,FHL1,ANK2,ANK3,SNAP25,ATP1A2,ATP1A3,CAB39,ABCC8,NPPA,KCNK10,P2RY12,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9" GO: Biological Process GO:0048858 cell projection morphogenesis 6.91E-12 4.53E-08 1.11E-09 1.04E-08 91 904 "MAG,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,USP33,TNIK,SPART,NFASC,NCAM1,CLASP2,KIRREL3,ARHGEF7,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,GPM6A,DDR1,HAP1,CAMK2A,BRSK2,GRIN1,OMG,NEURL1,PAX6,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,HNRNPK,NLGN3,NRXN1,SEMA5B,FLRT1,PLXNB3,SPATA6,PACSIN1,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,PRKCZ,CTNND2,MAPK8,DPYSL5,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,RFX4,ATL1,VANGL2,EFNA3,ELAVL4,PLEKHO1" GO: Biological Process GO:0043269 regulation of ion transport 9.18E-12 6.02E-08 1.43E-09 1.34E-08 74 669 "TTYH1,ABAT,ACTN2,KCNIP2,ADCYAP1R1,ADORA1,AGT,SCN3A,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,ATP2B2,GABBR1,SCN3B,CAB39,AHCYL1,JPH4,ABCC8,GNAS,CACNA1A,GPM6B,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,CAMK2A,CAMK2G,GRIN1,P2RX7,KCNK10,HRH3,PDE4B,PIRT,BEST3,CHRM1,CHRNB2,NLGN3,SERPINE2,NRXN1,CNTN1,BEST1,P2RY12,NKAIN4,NOS1AP,PTAFR,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNMA1,KCNQ2,NKAIN1,DNM2,DPP6,RASGRF1,RTN4,CACNG7" GO: Biological Process GO:0032990 cell part morphogenesis 1.02E-11 6.71E-08 1.56E-09 1.46E-08 92 925 "MAG,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,USP33,TNIK,SPART,NFASC,NCAM1,CLASP2,KIRREL3,ARHGEF7,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,CACNA1A,GPM6A,DDR1,HAP1,CAMK2A,BRSK2,GRIN1,OMG,NEURL1,PAX6,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,HNRNPK,NLGN3,NRXN1,SEMA5B,FLRT1,PLXNB3,SPATA6,PACSIN1,POU3F2,CRMP1,PPP3CB,FEZ2,FEZ1,DOCK7,PRKCZ,CTNND2,MAPK8,DPYSL5,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,PID1,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,RFX4,ATL1,VANGL2,EFNA3,ELAVL4,PLEKHO1" GO: Biological Process GO:0015672 monovalent inorganic cation transport 1.08E-11 7.07E-08 1.61E-09 1.50E-08 70 617 "ABAT,ASIC1,ACTN2,KCNIP2,ADORA1,ADORA3,SLC44A5,AGT,SCN3A,SCN4B,SCNN1D,FGF14,ASIC4,FHL1,ANK1,ANK2,ANK3,SLC8A2,SLC8A3,SNAP25,ATP1A2,ATP1A3,GABBR1,SCN3B,CAB39,AHCYL1,ABCC8,GNAS,CACNA1A,GPM6B,NPPA,AZIN2,CCKBR,P2RX7,KCNK10,HRH3,ASIC3,CHRNB2,SERPINE2,CNTN1,SLC25A27,P2RY12,NKAIN4,KCNT2,PRKAB2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,NKAIN1,DNM2,SLC17A6,DPP6,RTN4,ABCC9,SLC6A15,SLC4A10" GO: Biological Process GO:0030001 metal ion transport 1.18E-11 7.73E-08 1.72E-09 1.61E-08 87 855 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,ADCYAP1R1,RYR1,ADORA1,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,SLC30A10,ANK2,ANK3,RASA3,CACHD1,SLC8A2,SLC8A3,MT3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,SCN3B,CAB39,AHCYL1,JPH4,ABCC8,GNAS,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,HAP1,CAMK2A,CAMK2G,GRIN1,TF,P2RX7,KCNK10,PDE2A,PDE4B,ASIC3,CHRNB2,SERPINE2,CNTN1,BEST1,P2RY12,CP,NKAIN4,KCNT2,NOS1AP,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,NKAIN1,DNM2,SLC17A6,DPP6,ABCC9,SLC6A15,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0000902 cell morphogenesis 1.28E-11 8.38E-08 1.82E-09 1.71E-08 119 1337 "MAG,EPS8,MAP6,MAPT,ACHE,MBP,DSCAML1,SLITRK1,CDC7,ERMN,DRAXIN,SEMA6A,FGR,FOXG1,SOX6,SEMA6C,ANK3,ANXA7,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,ATP2B2,PALLD,USP33,TNIK,ADAM15,SPART,NFASC,NCAM1,CLASP2,KIRREL3,PHLDB1,ARHGEF7,SYT4,SEMA4A,ROBO3,NODAL,UNC5D,CNTN2,CACNA1A,GPM6A,DDR1,TCF7L2,HAP1,CAMK2A,BRSK2,GRIN1,OMG,TGFBR3,P2RX7,NEURL1,MAEL,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,HNRNPK,NLGN3,CADM1,NRXN1,SEMA5B,FLRT1,PLXNB3,SPATA6,PACSIN1,FAT3,POU3F2,MED1,CRMP1,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,PROX1,DPYSL5,ITGAV,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,WIPF2,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,RFX4,JMJD1C,ATL1,VANGL2,SIDT2,EFNA3,ELAVL4,PLEKHO1,TMEM100,EPB41,EPB41L2" GO: Biological Process GO:0051961 negative regulation of nervous system development 1.88E-11 1.23E-07 2.63E-09 2.46E-08 45 309 "MAG,MBP,CEND1,DRAXIN,DISP3,SEMA6A,FOXG1,SEMA6C,APBB1,NLGN1,MT3,ASCL1,SLIT1,DLL3,NRG3,NKX6-2,RAP1GAP2,SPART,GFAP,NKX2-2,SEMA4A,CNTN2,OMG,PAX6,TNR,GPR37L1,ADGRG1,HNRNPK,NLGN3,SEMA5B,FAT3,MED1,CRMP1,RBPJ,PRKACB,HES5,RGMA,PTPRO,PTPRZ1,NTM,RAP1GAP,RTN4,RFX4,OLIG2,SEZ6" GO: Biological Process GO:0007626 locomotory behavior 2.71E-11 1.78E-07 3.70E-09 3.46E-08 38 234 "EPS8,ABAT,MAPT,CEND1,FGF14,APBA2,ASTN1,SNAP25,ATP1A2,ATP1A3,ATP2B2,NPAS3,DDHD2,CNTN2,ADGRL3,CACNA1A,CACNA1E,GRIN1,GPR88,USP2,TNR,SEZ6L,CIART,CHRNB2,NEGR1,PPP3CB,MAPK10,PUM1,KCNJ10,PCDH15,KCNMA1,NAV2,DSCAM,PAK5,SLC4A10,ELAVL4,RCAN2,SEZ6" GO: Biological Process GO:0006812 cation transport 3.38E-11 2.21E-07 4.52E-09 4.23E-08 103 1110 "TTYH1,ABAT,ASIC1,ACTN2,KCNIP2,SLC25A25,ADCYAP1R1,RYR1,ADORA1,ADORA3,SLC44A5,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,SLC30A10,ANK1,ANK2,ANK3,RASA3,CACHD1,SLC6A9,SLC8A2,SLC8A3,MT3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SCN3B,CAB39,AHCYL1,JPH4,ABCC8,GNAS,CACNA1A,GPM6A,GPM6B,CACNA1E,NPPA,CACNB2,HAP1,AZIN2,CAMK2A,CAMK2G,GRIN1,ATP13A2,TF,CCKBR,P2RX7,KCNK10,HRH3,PDE2A,PDE4B,PIRT,ASIC3,CHRNB2,SERPINE2,CNTN1,SLC25A27,BEST1,P2RY12,SLC36A4,CP,NKAIN4,KCNT2,PRKAB2,NOS1AP,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,NKAIN1,DNM2,SLC17A6,DPP6,RTN4,ABCC9,SLC6A15,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0045595 regulation of cell differentiation 4.23E-11 2.77E-07 5.55E-09 5.20E-08 140 1699 "MAG,MAPT,ACHE,APC2,MBP,ADGRV1,EYA1,ATAT1,DRAXIN,AGT,KIAA1109,DISP3,LRRC7,SEMA6A,FOXG1,SOX6,SEMA6C,PI16,APBB1,APC,NLGN1,LRRC4C,SHTN1,MSR1,MT3,CCDC88A,ASCL1,SLIT1,DLL3,CAPRIN2,BRINP2,SNAP25,NRG3,FYN,TNIK,SOX5,ZCCHC24,SOX10,NKX6-2,NAP1L2,RAP1GAP2,SPART,LMO3,CLASP2,SMOC1,GFAP,NELL1,PHLDB1,NEUROD1,ARHGEF7,C1QC,SYT4,NKX2-2,SEMA4A,GNAS,NODAL,UNC5D,MMD2,CNTN2,CACNA1A,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,DDR2,GRIN1,TF,OMG,PTPN5,TGFBR3,NEURL1,PAX6,CDC42,TNR,RBFOX2,ZMYND8,FNDC5,GPR37L1,ADGRG1,HMGB1,PLEKHB1,CHRNB2,HNRNPK,NLGN3,SERPINE2,SEMA5B,NEGR1,TJP2,FTO,PLXNB3,CNTN1,PRRX1,P2RY12,PACSIN1,FAT3,POU3F2,MED1,CRMP1,TENM4,RGS6,CSF3R,FEZ1,CHD5,RBPJ,DOCK7,CMTM5,PRKCZ,HES5,PROX1,BRINP3,KLK6,ZBTB16,PLPPR5,PTCH1,ITGAV,PTHLH,LRP8,RGMA,MAGI2,BLOC1S6,PTPRD,PTPRO,PTPRZ1,NTM,CCDC3,DNM2,FAM57B,RAP1GAP,DSCAM,RTN4,L1CAM,RET,SLC39A12,EFNA3,ELAVL4,OLIG2,TMEM100,SEZ6" GO: Biological Process GO:0045665 negative regulation of neuron differentiation 4.43E-11 2.90E-07 5.69E-09 5.33E-08 37 227 "MAG,MBP,DRAXIN,DISP3,SEMA6A,FOXG1,SEMA6C,APBB1,NLGN1,MT3,ASCL1,SLIT1,RAP1GAP2,SPART,GFAP,NKX2-2,SEMA4A,CNTN2,OMG,PAX6,TNR,GPR37L1,NLGN3,SEMA5B,FAT3,MED1,CRMP1,RBPJ,HES5,RGMA,PTPRO,PTPRZ1,NTM,RAP1GAP,RTN4,OLIG2,SEZ6" GO: Biological Process GO:0050769 positive regulation of neurogenesis 4.81E-11 3.16E-07 6.07E-09 5.69E-08 57 465 "MAG,MAPT,ACHE,LRRC7,SEMA6A,FOXG1,APBB1,NLGN1,SHTN1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SOX10,NKX6-2,NAP1L2,GFAP,NEUROD1,SYT4,NKX2-2,MMD2,ACSL6,VWC2,ZEB1,TCF12,HAP1,TF,PTPN5,NEURL1,PAX6,ZMYND8,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,TENM4,RGS6,FEZ1,PROX1,BRINP3,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DSCAM,RTN4,L1CAM,RET,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0032989 cellular component morphogenesis 5.24E-11 3.44E-07 6.49E-09 6.08E-08 123 1430 "MAG,EPS8,MAP6,MAPT,ACHE,MBP,ACTN2,DSCAML1,SLITRK1,CDC7,ERMN,DRAXIN,SEMA6A,FGR,FOXG1,SOX6,SEMA6C,ANK2,ANK3,ANXA7,APBB1,APC,NTNG1,GAS7,SLITRK3,NLGN1,LRRC4C,SHTN1,LRRC55,MT3,SLIT1,CAPRIN2,FYN,ATP2B2,PALLD,USP33,TNIK,ADAM15,SPART,NFASC,NCAM1,CLASP2,KIRREL3,PHLDB1,ARHGEF7,SYT4,SEMA4A,ROBO3,NODAL,UNC5D,CNTN2,CACNA1A,GPM6A,DDR1,TCF7L2,HAP1,CAMK2A,BRSK2,GRIN1,OMG,TGFBR3,P2RX7,NEURL1,MAEL,PAX6,CDC42,TNR,DCLK1,RBFOX2,LGI1,LRTM2,CHRNB2,HNRNPK,NLGN3,CADM1,NRXN1,SEMA5B,FLRT1,PLXNB3,SPATA6,PACSIN1,FAT3,POU3F2,MED1,CRMP1,TENM4,PPP3CB,FEZ2,FEZ1,RBPJ,DOCK7,PRKCZ,CTNND2,MAPK8,PROX1,DPYSL5,ITGAV,LRP8,RGMA,PTPRD,PLPPR4,PTPRO,PTPRZ1,PCDH15,WIPF2,PID1,DNM2,ABI1,DSCAM,RTN4,L1CAM,RET,RFX4,JMJD1C,ATL1,VANGL2,SIDT2,EFNA3,ELAVL4,PLEKHO1,TMEM100,EPB41,EPB41L2" GO: Biological Process GO:0007416 synapse assembly 6.16E-11 4.04E-07 7.48E-09 7.01E-08 29 148 "ACHE,SYNDIG1,SLITRK1,NLGN4X,LRRTM4,SLITRK3,NLGN1,CLSTN1,SHANK2,SLIT1,ADGRB2,DNER,KIRREL3,ADGRL3,CACNA1A,GPM6A,GRIN1,LRTM2,CHRNB2,NLGN3,CADM1,NRXN1,NRXN2,FLRT1,LRRTM3,MAGI2,PTPRD,DSCAM,CBLN2" GO: Biological Process GO:0050890 cognition 1.24E-10 8.11E-07 1.47E-08 1.37E-07 43 303 "ASIC1,ADORA1,NLGN4X,PLA2G6,AMPH,APBB1,SLC8A2,SLC8A3,SHANK2,PDE8B,SORCS3,SNAP25,ATP1A2,ATP1A3,FYN,JPH4,NCAM1,GNAS,DDHD2,CNTN2,CACNA1E,NRGN,GRIA1,GRIN1,KCNK10,TNR,HRH3,CHRM1,CHRNB2,NLGN3,NRXN1,NRXN2,PPP3CB,PRKCG,PRKCZ,CTNND2,PTPRZ1,KCNK2,RASGRF1,PAK5,ABI2,ELAVL4,RCAN2" GO: Biological Process GO:0007612 learning 1.25E-10 8.21E-07 1.47E-08 1.37E-07 30 162 "ASIC1,NLGN4X,AMPH,APBB1,SLC8A2,SLC8A3,SHANK2,PDE8B,SORCS3,SNAP25,ATP1A2,ATP1A3,FYN,JPH4,DDHD2,CNTN2,CACNA1E,NRGN,GRIN1,TNR,HRH3,CHRNB2,NLGN3,NRXN1,NRXN2,PPP3CB,CTNND2,PTPRZ1,PAK5,ELAVL4" GO: Biological Process GO:0007611 learning or memory 1.66E-10 1.09E-06 1.91E-08 1.79E-07 40 271 "ASIC1,NLGN4X,PLA2G6,AMPH,APBB1,SLC8A2,SLC8A3,SHANK2,PDE8B,SORCS3,SNAP25,ATP1A2,ATP1A3,FYN,JPH4,NCAM1,DDHD2,CNTN2,CACNA1E,NRGN,GRIA1,GRIN1,KCNK10,TNR,HRH3,CHRNB2,NLGN3,NRXN1,NRXN2,PPP3CB,PRKCG,PRKCZ,CTNND2,PTPRZ1,KCNK2,RASGRF1,PAK5,ABI2,ELAVL4,RCAN2" GO: Biological Process GO:0050768 negative regulation of neurogenesis 2.19E-10 1.44E-06 2.48E-08 2.32E-07 41 285 "MAG,MBP,DRAXIN,DISP3,SEMA6A,FOXG1,SEMA6C,APBB1,NLGN1,MT3,ASCL1,SLIT1,DLL3,NRG3,NKX6-2,RAP1GAP2,SPART,GFAP,NKX2-2,SEMA4A,CNTN2,OMG,PAX6,TNR,GPR37L1,ADGRG1,NLGN3,SEMA5B,FAT3,MED1,CRMP1,RBPJ,HES5,RGMA,PTPRO,PTPRZ1,NTM,RAP1GAP,RTN4,OLIG2,SEZ6" GO: Biological Process GO:0006813 potassium ion transport 3.79E-10 2.48E-06 4.21E-08 3.94E-07 35 222 "ACTN2,KCNIP2,ADORA1,FHL1,ANK2,ANK3,SNAP25,ATP1A2,ATP1A3,CAB39,ABCC8,NPPA,KCNK10,P2RY12,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9" GO: Biological Process GO:0030900 forebrain development 7.07E-10 4.64E-06 7.73E-08 7.24E-07 50 407 "ATAT1,ARID1A,FABP7,DRAXIN,FOXG1,BCAN,TACC2,SLC1A2,SLC8A3,ASCL1,SLIT1,NRG3,FYN,SOX1,SALL3,GART,NCAM1,KIRREL3,NEUROD1,DCLK2,CDK5R2,CNTN2,TCF7L2,NRGN,HAP1,GRIN1,PAX6,TNR,PCDH9,DCLK1,ADGRG1,CHRNB2,HNRNPK,POU3F2,POU3F4,CHD5,RBPJ,DOCK7,HES5,PROX1,LRP8,KCNA1,KCNC1,PTPRZ1,PEX5,RTN4,CRTAC1,RFX4,SLC4A10,OLIG2" GO: Biological Process GO:0098655 cation transmembrane transport 8.69E-10 5.70E-06 9.35E-08 8.75E-07 74 738 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,RYR1,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,SLC30A10,ANK2,ANK3,RASA3,SLC8A2,SLC8A3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,CAB39,JPH4,ABCC8,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,HAP1,GRIN1,ATP13A2,P2RX7,KCNK10,PDE2A,PDE4B,PIRT,ASIC3,CHRNB2,P2RY12,SLC36A4,KCNT2,PRKAB2,NOS1AP,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9,SLC6A15,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0098662 inorganic cation transmembrane transport 8.96E-10 5.88E-06 9.48E-08 8.88E-07 69 667 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,RYR1,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,SLC30A10,ANK2,ANK3,RASA3,SLC8A2,SLC8A3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,CAB39,JPH4,ABCC8,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,HAP1,GRIN1,P2RX7,KCNK10,PDE2A,PDE4B,ASIC3,P2RY12,KCNT2,PRKAB2,NOS1AP,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0098660 inorganic ion transmembrane transport 9.53E-10 6.25E-06 9.92E-08 9.29E-07 75 754 "TTYH1,ASIC1,ACTN2,KCNIP2,SLC25A25,RYR1,AGT,SCN3A,SCN4B,SCNN1D,PLA2G6,FGF14,ASIC4,FHL1,SLC30A10,ANK2,ANK3,RASA3,SLC8A2,SLC8A3,ASPH,SLN,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,CAB39,JPH4,ABCC8,ANO4,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,HAP1,GRIN1,ADAMTS8,P2RX7,KCNK10,PDE2A,PDE4B,BEST3,ANO5,ASIC3,BEST1,P2RY12,KCNT2,PRKAB2,NOS1AP,PTAFR,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DNM2,DPP6,ABCC9,SLC39A12,CACNG7,SLC4A10" GO: Biological Process GO:0006928 movement of cell or subcellular component 1.09E-09 7.16E-06 1.12E-07 1.05E-06 146 1882 "MAG,EPS8,PRR5L,MAPT,APC2,CEND1,ACTN2,F3,PLEKHG5,ADORA1,ADORA3,DRAXIN,AGT,SCN4B,FGF1,SEMA6A,FGR,FOXG1,SELL,SEMA6C,CDC42BPA,ANK2,ANK3,CNIH2,SH3GL2,APBB1,DOCK10,APC,CCDC80,DGKZ,SHTN1,ARHGAP5,CCDC88A,ASCL1,DNAH17,SLIT1,ASTN1,ATP1A2,NRG3,FYN,PALLD,SCN3B,USP33,MYBPC1,SOX1,KIF21B,SOX10,MYH7,ADAM15,KIF1B,DNER,NFASC,NCAM1,CLASP2,GFRA1,KIRREL3,ARHGEF7,SEMA4A,ROBO3,NODAL,CDK5R2,UNC5D,CNTN2,ADGRL3,WWC1,GPM6A,CACNA1E,DDR1,CACNB2,NRDC,HAP1,DDR2,RFFL,TF,OLR1,TGFBR3,TIE1,CELF3,NEURL1,CD81,PAX6,CDC42,TNR,PADI2,TNS1,DCLK1,RBFOX2,LGI1,TPM3,TPM4,PDE4B,ADGRG1,HMGB1,CHGA,TMEFF2,JAM2,SERPINE2,NRXN1,SEMA5B,ANLN,PIK3CD,VAV2,PLXNB3,P2RY12,FAT3,POU3F2,CRMP1,CSF3R,FEZ2,FEZ1,VCAN,RBPJ,DOCK7,SDC3,FMN2,PKN2,PRKCZ,MAPK8,NOS1AP,PROX1,DPYSL5,TUBB2B,SIRPA,PTAFR,ITGAV,ELMO1,LRP8,MAGI2,BLOC1S6,PTPRO,PTPRZ1,SRGAP3,PEX5,KIF2A,WIPF2,DNAH9,ABI1,DSCAM,RTN4,PAK5,L1CAM,RET,VANGL2,EFNA3,ABI2,PLEKHO1" GO: Biological Process GO:0035249 "synaptic transmission, glutamatergic" 1.31E-09 8.56E-06 1.32E-07 1.23E-06 20 83 "ADORA1,PLA2G6,CNIH2,NLGN1,SHANK2,ATP1A2,CACNA1A,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GRM3,CCKBR,TNR,CDH8,NLGN3,SERPINE2,NRXN1,CNIH3" GO: Biological Process GO:0032412 regulation of ion transmembrane transporter activity 1.67E-09 1.10E-05 1.66E-07 1.55E-06 32 201 "ACTN2,KCNIP2,AGT,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,SCN3B,CAB39,AHCYL1,JPH4,NPPA,CACNB2,HAP1,PDE4B,PIRT,NLGN3,NRXN1,NOS1AP,PTAFR,CNIH3,KCNJ11,DNM2,RASGRF1,CACNG7" GO: Biological Process GO:0010721 negative regulation of cell development 1.73E-09 1.13E-05 1.69E-07 1.58E-06 45 354 "MAG,MBP,DRAXIN,DISP3,SEMA6A,FOXG1,SEMA6C,PI16,APBB1,NLGN1,MT3,ASCL1,SLIT1,DLL3,NRG3,NKX6-2,RAP1GAP2,SPART,GFAP,NKX2-2,SEMA4A,NODAL,CNTN2,OMG,TGFBR3,PAX6,TNR,GPR37L1,ADGRG1,NLGN3,SEMA5B,TJP2,FAT3,MED1,CRMP1,RBPJ,HES5,RGMA,PTPRO,PTPRZ1,NTM,RAP1GAP,RTN4,OLIG2,SEZ6" GO: Biological Process GO:0099504 synaptic vesicle cycle 2.12E-09 1.39E-05 2.04E-07 1.91E-06 24 121 "SYT9,SYNDIG1,FGF14,AMPH,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,SYT4,CACNA1A,SYT6,P2RX7,NLGN3,NRXN1,PACSIN1,RIMS4,RIMS3,SYTL2,MAGI2,BLOC1S6,SYT15" GO: Biological Process GO:0001505 regulation of neurotransmitter levels 2.15E-09 1.41E-05 2.04E-07 1.91E-06 33 214 "ABAT,ASIC1,ACHE,SYT9,PPFIA1,NLGN1,RPH3A,SLC6A9,CADPS,SNAP25,ATP1A2,GAD2,CPLX2,GFAP,SYT4,CACNA1A,GPM6B,CAMK2A,SYT6,P2RX7,PAH,HRH3,NRXN1,NRXN2,PNKD,SNCAIP,RIMS4,RIMS3,SYTL2,BLOC1S6,KCNJ10,SLC17A6,SYT15" GO: Biological Process GO:0051094 positive regulation of developmental process 2.19E-09 1.44E-05 2.05E-07 1.92E-06 111 1323 "MAG,MAPT,ACHE,LGR4,SYNDIG1,F3,SLITRK1,AGT,LRRTM4,FGF1,LRRC7,SEMA6A,FOXG1,SOX6,APBB1,APC,GPAM,SLITRK3,NLGN1,SHTN1,CLSTN1,MSR1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SOX5,SOX10,NKX6-2,ADGRB2,NAP1L2,NCAM1,LMO3,CLASP2,STOX1,GFAP,NELL1,PHLDB1,NEUROD1,ARHGEF7,SYT4,NKX2-2,GNAS,DDHD2,NODAL,MYRF,MMD2,ADGRL3,GPM6B,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,DDR2,TF,PTPN5,USP2,P2RX7,NEURL1,PAX6,CDC42,ZMYND8,FNDC5,GPR37L1,HMGB1,LRTM2,HNRNPK,NLGN3,SERPINE2,NRXN1,NEGR1,FLRT1,PLXNB3,CNTN1,PACSIN1,NSD2,POU3F2,MED1,TENM4,RGS6,FEZ1,RBPJ,PRKCZ,MAPK8,PROX1,BRINP3,ZBTB16,PLPPR5,LRRTM3,PTCH1,LRP8,RGMA,MAGI2,BLOC1S6,PTPRD,PTPRZ1,CCDC3,PEX5,DNM2,DSCAM,RTN4,L1CAM,RET,CBLN2,ELAVL4,OLIG2,TMEM100,SEZ6" GO: Biological Process GO:0097479 synaptic vesicle localization 2.36E-09 1.55E-05 2.18E-07 2.04E-06 26 141 "SYT9,SYNDIG1,FGF14,AMPH,CNIH2,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,SYT4,CACNA1A,SYT6,P2RX7,NLGN3,NRXN1,PACSIN1,RIMS4,RIMS3,SYTL2,MAGI2,BLOC1S6,DNM2,SYT15" GO: Biological Process GO:0010720 positive regulation of cell development 2.77E-09 1.82E-05 2.53E-07 2.37E-06 61 572 "MAG,MAPT,ACHE,LRRC7,SEMA6A,FOXG1,APBB1,NLGN1,SHTN1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SOX10,NKX6-2,NAP1L2,GFAP,NEUROD1,ARHGEF7,SYT4,NKX2-2,MMD2,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,TF,PTPN5,NEURL1,PAX6,CDC42,ZMYND8,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,TENM4,RGS6,FEZ1,PROX1,BRINP3,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DNM2,DSCAM,RTN4,L1CAM,RET,ELAVL4,OLIG2,SEZ6" GO: Biological Process GO:0022898 regulation of transmembrane transporter activity 3.12E-09 2.05E-05 2.81E-07 2.63E-06 32 206 "ACTN2,KCNIP2,AGT,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,SCN3B,CAB39,AHCYL1,JPH4,NPPA,CACNB2,HAP1,PDE4B,PIRT,NLGN3,NRXN1,NOS1AP,PTAFR,CNIH3,KCNJ11,DNM2,RASGRF1,CACNG7" GO: Biological Process GO:0050806 positive regulation of synaptic transmission 3.18E-09 2.09E-05 2.82E-07 2.64E-06 27 153 "ABAT,ADORA1,NLGN1,CLSTN1,SLC8A2,SLC8A3,SHANK2,IGSF9B,SNAP25,GFAP,NRGN,HAP1,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,CCKBR,PTPN5,TNR,LGI1,CHRNB2,HNRNPK,NLGN3,SERPINE2,NRXN1,PRKCZ" GO: Biological Process GO:0045666 positive regulation of neuron differentiation 3.92E-09 2.57E-05 3.43E-07 3.21E-06 46 376 "MAPT,ACHE,LRRC7,FOXG1,APBB1,NLGN1,SHTN1,ASCL1,CAPRIN2,BRINP2,FYN,NAP1L2,NEUROD1,SYT4,NKX2-2,MMD2,ACSL6,VWC2,ZEB1,TCF12,HAP1,PTPN5,NEURL1,ZMYND8,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,RGS6,FEZ1,PROX1,BRINP3,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DSCAM,L1CAM,RET,ELAVL4,SEZ6" GO: Biological Process GO:0034765 regulation of ion transmembrane transport 4.12E-09 2.70E-05 3.56E-07 3.33E-06 52 455 "ACTN2,KCNIP2,AGT,SCN3A,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,SCN3B,CAB39,AHCYL1,JPH4,CACNA1A,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,GRIN1,P2RX7,KCNK10,PDE4B,PIRT,NLGN3,NRXN1,NOS1AP,PTAFR,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNMA1,KCNQ2,DNM2,DPP6,RASGRF1,CACNG7" GO: Biological Process GO:0051640 organelle localization 4.45E-09 2.92E-05 3.79E-07 3.55E-06 56 510 "MAP6,MAPT,SYT9,SYNDIG1,EYA1,ADORA3,KIAA1109,FGF14,SEMA6A,FGR,AMPH,CDC42BPA,CNIH2,ITSN1,SH3GL2,TACC2,NLGN1,RPH3A,CADPS,SLIT1,SNAP25,ATM,KIF1B,CPLX2,CLASP2,SYT4,PSRC1,CACNA1A,TCF7L2,HAP1,SYT6,NUMA1,GRIA1,P2RX7,PAX6,CDC42,CHGA,NLGN3,NRXN1,PIK3CD,PACSIN1,ATCAY,FEZ1,RIMS4,DOCK7,FMN2,PRKCZ,RIMS3,SYTL2,SPIRE1,CNIH3,MAGI2,BLOC1S6,DNM2,C12orf4,SYT15" GO: Biological Process GO:0042063 gliogenesis 4.79E-09 3.14E-05 4.02E-07 3.77E-06 38 279 "MAG,AGT,FOXG1,SOX6,SLC8A3,MT3,ASCL1,DLL3,SOX5,ZCCHC24,SOX10,NKX6-2,DNER,GFAP,ARHGEF7,NKX2-2,MYRF,CDK5R2,CNTN2,TCF7L2,TF,OMG,PAX6,GPR37L1,ADGRG1,NLGN3,SERPINE2,P2RY12,POU3F2,TENM4,VCAN,HES5,LRP8,PTPRZ1,KCNJ10,OLIG1,RTN4,OLIG2" GO: Biological Process GO:0034762 regulation of transmembrane transport 5.80E-09 3.81E-05 4.82E-07 4.51E-06 53 473 "ACTN2,KCNIP2,AGT,SCN3A,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,SCN3B,CAB39,AHCYL1,JPH4,CACNA1A,ACSL6,CACNA1E,NPPA,CACNB2,HAP1,AZIN2,GRIN1,P2RX7,KCNK10,PDE4B,PIRT,NLGN3,NRXN1,NOS1AP,PTAFR,CNIH3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNMA1,KCNQ2,DNM2,DPP6,RASGRF1,CACNG7" GO: Biological Process GO:0006836 neurotransmitter transport 6.43E-09 4.22E-05 5.27E-07 4.94E-06 32 212 "ASIC1,SYT9,PPFIA1,NLGN1,RPH3A,SLC6A9,CADPS,SNAP25,ATP1A2,GAD2,CPLX2,GFAP,SYT4,CACNA1A,GPM6B,CAMK2A,SYT6,P2RX7,HRH3,NRXN1,NRXN2,PNKD,SNCAIP,RIMS4,RIMS3,SYTL2,BLOC1S6,SV2A,KCNJ10,SLC17A6,SLC6A15,SYT15" GO: Biological Process GO:0044057 regulation of system process 6.97E-09 4.57E-05 5.64E-07 5.28E-06 61 586 "MAG,ABAT,MRVI1,MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,PLA2G6,ANK2,PI16,NLGN1,MADD,SLC8A2,SLC8A3,ASPH,SLN,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,NCAM1,NEUROD1,GLS,GNAS,MYRF,CACNA1E,NPPA,CACNB2,CAMK2G,GRM3,TF,CCKBR,SPX,GUCY1A1,TNR,PDE4B,CHGA,CHRM1,NLGN3,FTO,TENM4,NOS1AP,PTAFR,KCNA1,PTPRO,KCND3,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNMA1,RTN4,ABCC9,CACNG7,FGFBP3,TMEM100" GO: Biological Process GO:0040011 locomotion 8.00E-09 5.25E-05 6.40E-07 6.00E-06 134 1735 "MAG,EPS8,PRR5L,MAPT,APC2,CEND1,F3,PLEKHG5,ADORA1,ADORA3,DRAXIN,AGT,FGF1,PLA2G6,SEMA6A,FGR,FOXG1,MOG,SELL,SEMA6C,CDC42BPA,ANK3,APBB1,DOCK10,APC,CCDC80,DGKZ,SHTN1,ARHGAP5,CCDC88A,ASCL1,DNAH17,SLIT1,ASTN1,ATP1A2,NRG3,FYN,ATP2B2,PALLD,USP33,SOX1,SOX10,ADAM15,DNER,NFASC,NCAM1,CLASP2,GFRA1,KIRREL3,ARHGEF7,SEMA4A,ROBO3,NODAL,CDK5R2,UNC5D,CNTN2,ADGRL3,WWC1,GPM6A,CACNA1E,DDR1,NRDC,DDR2,RFFL,TF,OLR1,TGFBR3,TIE1,CELF3,NEURL1,CD81,PAX6,CDC42,TNR,PADI2,TNS1,DCLK1,PTGDR2,RBFOX2,LGI1,PDE4B,ADGRG1,HMGB1,CHGA,CHRM1,CHRM4,TMEFF2,JAM2,SERPINE2,NRXN1,SEMA5B,ANLN,PIK3CD,VAV2,PLXNB3,P2RY12,FAT3,POU3F2,CRMP1,PPP3CB,CSF3R,FEZ2,FEZ1,VCAN,RBPJ,DOCK7,SDC3,CMTM5,PKN2,PRKCZ,MAPK8,PROX1,DPYSL5,TUBB2B,SIRPA,PTAFR,ITGAV,ELMO1,LRP8,MAGI2,PTPRO,PTPRZ1,SRGAP3,PEX5,DSCAM,RTN4,PAK5,L1CAM,RET,VANGL2,EFNA3,ABI2,PLEKHO1,RCAN2" GO: Biological Process GO:0007215 glutamate receptor signaling pathway 9.34E-09 6.12E-05 7.38E-07 6.91E-06 18 75 "CNIH2,NLGN1,ATP1A3,CAMK2A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,NLGN3,NRXN1,CNIH3,RASGRF1,CACNG7" GO: Biological Process GO:0032409 regulation of transporter activity 1.80E-08 1.18E-04 1.40E-06 1.31E-05 32 221 "ACTN2,KCNIP2,AGT,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,CNIH2,NLGN1,ASPH,SLN,ATP1A2,SCN3B,CAB39,AHCYL1,JPH4,NPPA,CACNB2,HAP1,PDE4B,PIRT,NLGN3,NRXN1,NOS1AP,PTAFR,CNIH3,KCNJ11,DNM2,RASGRF1,CACNG7" GO: Biological Process GO:0050770 regulation of axonogenesis 2.00E-08 1.31E-04 1.54E-06 1.45E-05 29 188 "MAG,MAPT,ACHE,MBP,DRAXIN,SEMA6A,SEMA6C,LRRC4C,SHTN1,MT3,SLIT1,SPART,CLASP2,SEMA4A,CNTN2,CACNA1A,GRIN1,OMG,TNR,SEMA5B,PLXNB3,POU3F2,RGMA,PTPRO,DNM2,DSCAM,RTN4,L1CAM,RET" GO: Biological Process GO:0050807 regulation of synapse organization 2.40E-08 1.57E-04 1.83E-06 1.71E-05 23 126 "SYNDIG1,SLITRK1,LRRTM4,SLITRK3,NLGN1,CLSTN1,SLIT1,ADGRB2,ADGRL3,GRIN1,NEURL1,CDC42,ZMYND8,LRTM2,CHRNB2,HNRNPK,NLGN3,NRXN1,FLRT1,NCAN,LRRTM3,MAGI2,CBLN2" GO: Biological Process GO:0043270 positive regulation of ion transport 2.53E-08 1.66E-04 1.91E-06 1.79E-05 37 284 "ABAT,ACTN2,ADCYAP1R1,ADORA1,AGT,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,ASPH,ATP2B2,GABBR1,SCN3B,AHCYL1,ABCC8,GNAS,ACSL6,NPPA,CACNB2,HAP1,CAMK2A,P2RX7,PIRT,CHRM1,CHRNB2,NLGN3,CNTN1,P2RY12,NOS1AP,PTAFR,KCNC1,KCNJ11,DNM2,DPP6,RTN4" GO: Biological Process GO:0031345 negative regulation of cell projection organization 2.57E-08 1.69E-04 1.91E-06 1.79E-05 28 179 "MAG,MBP,DRAXIN,SEMA6A,SEMA6C,NLGN1,MT3,SLIT1,RAP1GAP2,SPART,GFAP,SEMA4A,OMG,TNR,NLGN3,NRXN1,SEMA5B,PLXNB3,FAT3,CRMP1,RBPJ,RGMA,PTPRO,PTPRZ1,NTM,RAP1GAP,RTN4,SEZ6" GO: Biological Process GO:0001764 neuron migration 3.64E-08 2.38E-04 2.68E-06 2.51E-05 26 160 "MAPT,SEMA6A,FOXG1,APBB1,SHTN1,ASCL1,ASTN1,NRG3,FYN,SOX1,DNER,KIRREL3,ROBO3,CDK5R2,UNC5D,CNTN2,ADGRL3,GPM6A,PAX6,DCLK1,ADGRG1,FAT3,MAPK8,TUBB2B,PTPRZ1,PEX5" GO: Biological Process GO:0048589 developmental growth 4.08E-08 2.67E-04 2.97E-06 2.78E-05 65 673 "MAPT,SLC25A25,SLITRK1,NLGN4X,DRAXIN,AGT,FGF1,SEMA6A,UNC79,SEMA6C,PI16,APBA2,GPAM,SHTN1,SLC1A2,MT3,SLIT1,WDTC1,SOX10,ADAM15,SPART,NCAM1,CLASP2,SYT4,SEMA4A,GNAS,WWC1,DDR1,NPPA,TCF7L2,DDR2,OMG,TGFBR3,TLL2,MAEL,CDC42,TNR,DCLK1,HNRNPK,NLGN3,CADM1,SEMA5B,FLRT1,FTO,POU3F2,MED1,TENM4,PPP3CB,RBPJ,PRKCZ,PROX1,KLK6,PTCH1,PTHLH,RGMA,MAGI2,KCNK2,PCDH15,PEX5,DNM2,DSCAM,RTN4,L1CAM,VANGL2,SLC4A10" GO: Biological Process GO:0050905 neuromuscular process 4.44E-08 2.91E-04 3.20E-06 3.00E-05 22 120 "FABP7,FGF14,PDE8B,ATP2B2,JPH4,NKX6-2,NPAS3,SPART,CAMTA1,CACNA1A,GRIN1,GPR88,TNR,RBFOX2,NRXN1,PNKD,KCNA1,KCNH1,PCDH15,KCNMA1,PEX5,USH1C" GO: Biological Process GO:0016477 cell migration 4.57E-08 2.99E-04 3.25E-06 3.05E-05 105 1300 "MAG,EPS8,PRR5L,MAPT,APC2,CEND1,F3,PLEKHG5,ADORA1,ADORA3,AGT,FGF1,SEMA6A,FGR,FOXG1,SELL,SEMA6C,CDC42BPA,APBB1,DOCK10,APC,DGKZ,SHTN1,ARHGAP5,CCDC88A,ASCL1,SLIT1,ASTN1,NRG3,FYN,PALLD,USP33,SOX1,SOX10,ADAM15,DNER,CLASP2,GFRA1,KIRREL3,ARHGEF7,SEMA4A,ROBO3,NODAL,CDK5R2,UNC5D,CNTN2,ADGRL3,WWC1,GPM6A,DDR1,NRDC,DDR2,RFFL,OLR1,TGFBR3,TIE1,PAX6,CDC42,TNR,PADI2,TNS1,DCLK1,RBFOX2,PDE4B,ADGRG1,HMGB1,CHGA,TMEFF2,JAM2,SERPINE2,SEMA5B,ANLN,PIK3CD,VAV2,PLXNB3,P2RY12,FAT3,POU3F2,CSF3R,VCAN,RBPJ,DOCK7,SDC3,PKN2,PRKCZ,MAPK8,PROX1,TUBB2B,SIRPA,PTAFR,ITGAV,ELMO1,LRP8,MAGI2,PTPRO,PTPRZ1,SRGAP3,PEX5,RTN4,PAK5,L1CAM,RET,VANGL2,ABI2,PLEKHO1" GO: Biological Process GO:0060341 regulation of cellular localization 4.71E-08 3.09E-04 3.32E-06 3.11E-05 112 1416 "ABAT,ASIC1,MAPT,ACHE,APC2,SYT9,LGR4,ACTN2,WLS,ADCYAP1R1,ADORA1,ADORA3,AGT,PLA2G6,FGF14,FGR,ELMOD1,ANK2,ANK3,CNIH2,PPFIA1,APBB1,APC,GPAM,SORBS1,SYBU,NLGN1,RPH3A,MADD,CADPS,PDE8B,LGI3,ASPH,SNAP25,ATP1A2,FYN,GABBR1,MYBPC1,JPH4,CPLX2,NCAM1,CLASP2,NEUROD1,MLC1,ARHGEF7,ABCC8,OS9,SYT4,ASTN2,DCLK2,GNAS,NODAL,CDK5R2,WWC1,CACNA1A,GPM6B,CACNA1E,TCF7L2,CLEC9A,GPR26,HAP1,CAMK2A,SYT6,NUCB1,BRSK2,ATP13A2,CCKBR,PTPN5,P2RX7,PAX6,CDC42,DCLK1,HRH3,ZNF384,PDE1C,PDE2A,PDE3B,ZMYND8,HMGB1,CHGA,CHRM1,CHRNB2,HNRNPK,HPCA,NLGN3,CADM1,NRXN1,CABP1,P2RY12,MED1,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCZ,MAPK8,RIMS3,SYTL2,PTAFR,MAGI2,KCNA2,PARD6A,KCNJ11,KCNN3,PID1,DPP6,C12orf4,GOPC,RTN4,SYT15,SIDT2,SH3GLB1" GO: Biological Process GO:0010977 negative regulation of neuron projection development 5.19E-08 3.41E-04 3.62E-06 3.39E-05 25 152 "MAG,MBP,DRAXIN,SEMA6A,SEMA6C,NLGN1,MT3,SLIT1,RAP1GAP2,SPART,GFAP,SEMA4A,OMG,TNR,NLGN3,SEMA5B,FAT3,CRMP1,RBPJ,RGMA,PTPRO,PTPRZ1,NTM,RTN4,SEZ6" GO: Biological Process GO:0050877 nervous system process 5.80E-08 3.80E-04 4.00E-06 3.75E-05 111 1405 "MAG,RPL38,ASIC1,MBP,ADGRV1,EYA1,FABP7,ADORA1,NLGN4X,AGT,SCN3A,SCNN1D,PLA2G6,FGF14,AMPH,ANK3,APBB1,NLGN1,AQP4,SLC8A2,SLC8A3,SHANK2,RTP5,PDE8B,SORCS3,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,SCN3B,JPH4,NKX6-2,NPAS3,SPART,NFASC,NCAM1,GLS,GNAS,DDHD2,CAMTA1,MYRF,CNTN2,CACNA1A,CACNA1E,CACNB2,NRGN,GRIA1,GRIK2,GRIN1,GPR88,GRM3,TF,CCKBR,SPX,P2RX7,TJP1,KCNK10,PAX6,TNR,RBFOX2,HRH3,PDE1C,PDYN,NTSR2,ASIC3,CHRM1,TUB,CHRNB2,NLGN3,SERPINE2,NRXN1,NRXN2,SEMA5B,BEST1,POU3F4,PNKD,TENM4,PPP3CB,PRKCG,PRKCZ,CTNND2,PTAFR,KCNA1,KCNA2,PTPRZ1,KCNH1,KCNJ10,KCNJ11,KCNK2,PCDH15,KCNMA1,NAV2,PEX5,KCNQ2,DLG2,DPP6,RASGRF1,RTN4,PAK5,USH1C,RGR,RLBP1,CACNG7,ABI2,FGFBP3,ELAVL4,ROM1,RPE65,TMEM100,RCAN2" GO: Biological Process GO:0007270 neuron-neuron synaptic transmission 6.77E-08 4.44E-04 4.63E-06 4.33E-05 25 154 "ADORA1,PLA2G6,CNIH2,NLGN1,SLC6A9,SHANK2,ATP1A2,KIF1B,CACNA1A,HAP1,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GRM3,CCKBR,TNR,CDH8,CHRNB2,NLGN3,SERPINE2,NRXN1,PNKD,CNIH3" GO: Biological Process GO:0051966 "regulation of synaptic transmission, glutamatergic" 6.99E-08 4.59E-04 4.73E-06 4.43E-05 15 59 "ADORA1,PLA2G6,NLGN1,SHANK2,ATP1A2,GRIA2,GRIA4,GRIK2,GRIK3,GRM3,CCKBR,TNR,NLGN3,SERPINE2,NRXN1" GO: Biological Process GO:0048709 oligodendrocyte differentiation 7.25E-08 4.76E-04 4.79E-06 4.48E-05 19 94 "SOX6,SLC8A3,ASCL1,SOX5,SOX10,NKX6-2,NKX2-2,MYRF,CNTN2,TCF7L2,OMG,PAX6,NLGN3,TENM4,HES5,PTPRZ1,KCNJ10,OLIG1,OLIG2" GO: Biological Process GO:0051674 localization of cell 7.35E-08 4.82E-04 4.79E-06 4.48E-05 112 1428 "MAG,EPS8,PRR5L,MAPT,APC2,CEND1,F3,PLEKHG5,ADORA1,ADORA3,AGT,FGF1,SEMA6A,FGR,FOXG1,SELL,SEMA6C,CDC42BPA,APBB1,DOCK10,APC,CCDC80,DGKZ,SHTN1,ARHGAP5,CCDC88A,ASCL1,DNAH17,SLIT1,ASTN1,NRG3,FYN,PALLD,USP33,SOX1,SOX10,ADAM15,DNER,CLASP2,GFRA1,KIRREL3,ARHGEF7,SEMA4A,ROBO3,NODAL,CDK5R2,UNC5D,CNTN2,ADGRL3,WWC1,GPM6A,CACNA1E,DDR1,NRDC,DDR2,RFFL,TF,OLR1,TGFBR3,TIE1,CELF3,NEURL1,CD81,PAX6,CDC42,TNR,PADI2,TNS1,DCLK1,RBFOX2,PDE4B,ADGRG1,HMGB1,CHGA,TMEFF2,JAM2,SERPINE2,SEMA5B,ANLN,PIK3CD,VAV2,PLXNB3,P2RY12,FAT3,POU3F2,CSF3R,VCAN,RBPJ,DOCK7,SDC3,PKN2,PRKCZ,MAPK8,PROX1,TUBB2B,SIRPA,PTAFR,ITGAV,ELMO1,LRP8,MAGI2,PTPRO,PTPRZ1,SRGAP3,PEX5,RTN4,PAK5,L1CAM,RET,VANGL2,ABI2,PLEKHO1" GO: Biological Process GO:0048870 cell motility 7.35E-08 4.82E-04 4.79E-06 4.48E-05 112 1428 "MAG,EPS8,PRR5L,MAPT,APC2,CEND1,F3,PLEKHG5,ADORA1,ADORA3,AGT,FGF1,SEMA6A,FGR,FOXG1,SELL,SEMA6C,CDC42BPA,APBB1,DOCK10,APC,CCDC80,DGKZ,SHTN1,ARHGAP5,CCDC88A,ASCL1,DNAH17,SLIT1,ASTN1,NRG3,FYN,PALLD,USP33,SOX1,SOX10,ADAM15,DNER,CLASP2,GFRA1,KIRREL3,ARHGEF7,SEMA4A,ROBO3,NODAL,CDK5R2,UNC5D,CNTN2,ADGRL3,WWC1,GPM6A,CACNA1E,DDR1,NRDC,DDR2,RFFL,TF,OLR1,TGFBR3,TIE1,CELF3,NEURL1,CD81,PAX6,CDC42,TNR,PADI2,TNS1,DCLK1,RBFOX2,PDE4B,ADGRG1,HMGB1,CHGA,TMEFF2,JAM2,SERPINE2,SEMA5B,ANLN,PIK3CD,VAV2,PLXNB3,P2RY12,FAT3,POU3F2,CSF3R,VCAN,RBPJ,DOCK7,SDC3,PKN2,PRKCZ,MAPK8,PROX1,TUBB2B,SIRPA,PTAFR,ITGAV,ELMO1,LRP8,MAGI2,PTPRO,PTPRZ1,SRGAP3,PEX5,RTN4,PAK5,L1CAM,RET,VANGL2,ABI2,PLEKHO1" GO: Biological Process GO:0050805 negative regulation of synaptic transmission 7.37E-08 4.83E-04 4.79E-06 4.48E-05 17 76 "ASIC1,MAPT,ACHE,ADORA1,NLGN4X,PLA2G6,CNIH2,SHANK2,SORCS3,GABBR1,GPM6B,GRIA1,GRIK2,GRIK3,TNR,NLGN3,PNKD" GO: Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway 9.41E-08 6.17E-04 6.05E-06 5.67E-05 10 25 "ATP1A3,CAMK2A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" GO: Biological Process GO:0022610 biological adhesion 1.19E-07 7.80E-04 7.53E-06 7.05E-05 118 1542 "MAG,TTYH1,ABAT,ACHE,CDHR1,CNTNAP3,ACTN2,ADGRV1,DSCAML1,NLGN4X,TESK2,AGT,MOG,SELL,ANK3,PPFIA1,PKP4,APC,CCDC80,GPAM,BCAN,SORBS1,NLGN1,CLSTN1,ARHGAP5,CGREF1,ASTN1,IGSF9B,FYN,MEGF11,MYBPC1,CADM3,ADAM15,NFASC,NCAM1,CLASP2,SMOC1,ERBIN,KIRREL3,RND1,AJAP1,ARHGEF7,PCDH11X,SEMA4A,GNAS,NODAL,UNC5D,CNTN2,ADGRL3,GPM6B,VWC2,DDR1,ZEB1,PCDHGA3,DDR2,OLR1,OMG,OPCML,P2RX7,CD81,CDC42,TNR,PCDH8,PCDH9,CDH8,CDH10,MAGI1,PDE3B,HAPLN2,ADGRG1,HMGB1,JAM2,HEPACAM,DUSP26,NLGN3,SERPINE2,CADM1,NRXN1,NRXN2,NEGR1,PIK3CD,FLRT1,PLXNB3,CNTN1,P2RY12,FAT3,PPP3CB,CSF3R,FEZ1,VCAN,NCAN,RBPJ,SDC3,PKN2,PRKCZ,CTNND1,CTNND2,HES5,ZBTB16,SIRPA,PTAFR,ITGAV,CADM2,CDH20,PTPRD,PTPRO,PTPRZ1,NTM,PCDH15,DNM2,RAP1GAP,DSCAM,GNE,L1CAM,RET,SSPN,LMO1,ROM1" GO: Biological Process GO:0097090 presynaptic membrane organization 1.19E-07 7.83E-04 7.53E-06 7.05E-05 8 15 "NLGN4X,LRRTM4,NLGN1,CNTN2,NLGN3,NRXN1,MAGI2,PTPRD" GO: Biological Process GO:0046903 secretion 1.26E-07 8.28E-04 7.83E-06 7.34E-05 99 1228 "RABEPK,SERPINA3,ABAT,ASIC1,ACHE,SYT9,LGR4,ACTN2,WLS,ADORA1,ADORA3,AGT,PLA2G6,FGR,ANK1,PPFIA1,APBB1,GPAM,SYBU,NLGN1,SLC1A2,SLC1A6,RPH3A,SLC1A7,MADD,SLC6A9,CADPS,PDE8B,SCG3,LGI3,SNAP25,ATP2B2,GABBR1,ILDR2,GAD2,STARD10,CPLX2,NCAM1,CLASP2,NEUROD1,ARHGEF7,ABCC8,GLS,VAMP1,SYT4,GNAS,CDK5R2,CACNA1A,CACNA1E,DDR1,TCF7L2,CLEC9A,HAP1,CAMK2A,CAMK2G,SYT6,BRSK2,ATP13A2,TF,CCKBR,SPX,LEFTY2,P2RX7,NEURL1,PAX6,HRH3,TPD52,ZNF384,PDE1C,PDE3B,HMGB1,CHGA,CHRM1,CHRNB2,SLC22A6,SERPINE2,CADM1,NRXN1,NRXN2,PIK3CD,P2RY12,MED1,PNKD,SNCAIP,PPP3CB,RIMS4,RBPJ,PRKCZ,RIMS3,SYTL2,PTAFR,BLOC1S6,KCNA2,KCNJ11,KCNMA1,C12orf4,RTN4,SYT15,SIDT2" GO: Biological Process GO:0030534 adult behavior 1.28E-07 8.38E-04 7.83E-06 7.34E-05 26 170 "EPS8,ABAT,MAPT,CEND1,SLITRK1,NLGN4X,FGF14,UNC79,SLC1A2,SHANK2,ATP1A2,ATP1A3,CNTN2,CACNA1A,GRIN1,SEZ6L,CHRNB2,NLGN3,NRXN1,NRXN2,PUM1,KCNJ10,PCDH15,KCNMA1,FGFBP3,SEZ6" GO: Biological Process GO:0030902 hindbrain development 1.28E-07 8.38E-04 7.83E-06 7.34E-05 26 170 "ABAT,CEND1,WLS,NLGN4X,ASCL1,ATP2B2,GART,NEUROD1,CDK5R2,CACNA1A,HAP1,PTBP2,GRIN1,PAX6,RBFOX2,SEZ6L,GPR37L1,HNRNPK,SERPINE2,NRXN1,CNTN1,PROX1,KCNC1,RFX4,EN2,SEZ6" GO: Biological Process GO:0007155 cell adhesion 1.41E-07 9.22E-04 8.54E-06 8.00E-05 117 1530 "MAG,TTYH1,ABAT,ACHE,CDHR1,CNTNAP3,ACTN2,ADGRV1,DSCAML1,NLGN4X,TESK2,AGT,MOG,SELL,ANK3,PPFIA1,PKP4,APC,CCDC80,GPAM,BCAN,SORBS1,NLGN1,CLSTN1,ARHGAP5,CGREF1,ASTN1,IGSF9B,FYN,MEGF11,MYBPC1,CADM3,ADAM15,NFASC,NCAM1,CLASP2,SMOC1,ERBIN,KIRREL3,RND1,AJAP1,ARHGEF7,PCDH11X,SEMA4A,GNAS,NODAL,UNC5D,CNTN2,ADGRL3,GPM6B,VWC2,DDR1,ZEB1,PCDHGA3,DDR2,OLR1,OMG,OPCML,P2RX7,CDC42,TNR,PCDH8,PCDH9,CDH8,CDH10,MAGI1,PDE3B,HAPLN2,ADGRG1,HMGB1,JAM2,HEPACAM,DUSP26,NLGN3,SERPINE2,CADM1,NRXN1,NRXN2,NEGR1,PIK3CD,FLRT1,PLXNB3,CNTN1,P2RY12,FAT3,PPP3CB,CSF3R,FEZ1,VCAN,NCAN,RBPJ,SDC3,PKN2,PRKCZ,CTNND1,CTNND2,HES5,ZBTB16,SIRPA,PTAFR,ITGAV,CADM2,CDH20,PTPRD,PTPRO,PTPRZ1,NTM,PCDH15,DNM2,RAP1GAP,DSCAM,GNE,L1CAM,RET,SSPN,LMO1,ROM1" GO: Biological Process GO:0060560 developmental growth involved in morphogenesis 1.57E-07 1.03E-03 9.42E-06 8.83E-05 32 242 "MAPT,DRAXIN,FGF1,SEMA6A,SEMA6C,SHTN1,MT3,SLIT1,SPART,CLASP2,SYT4,SEMA4A,DDR1,OMG,TNR,DCLK1,HNRNPK,NLGN3,CADM1,SEMA5B,FLRT1,MED1,PPP3CB,PRKCZ,PTHLH,RGMA,MAGI2,DNM2,DSCAM,RTN4,L1CAM,VANGL2" GO: Biological Process GO:0023061 signal release 2.05E-07 1.35E-03 1.22E-05 1.15E-04 51 498 "ABAT,ASIC1,SYT9,WLS,ADORA1,ADORA3,AGT,PLA2G6,PPFIA1,SYBU,NLGN1,RPH3A,MADD,SLC6A9,CADPS,PDE8B,SNAP25,GABBR1,ILDR2,GAD2,CPLX2,NEUROD1,ARHGEF7,ABCC8,SYT4,GNAS,CACNA1A,CACNA1E,TCF7L2,CAMK2A,CAMK2G,SYT6,BRSK2,CCKBR,P2RX7,PAX6,HRH3,PDE1C,PDE3B,NRXN1,NRXN2,PNKD,SNCAIP,PPP3CB,RIMS4,RIMS3,SYTL2,BLOC1S6,KCNJ11,SYT15,SIDT2" GO: Biological Process GO:0099643 signal release from synapse 2.10E-07 1.38E-03 1.22E-05 1.15E-04 25 163 "ASIC1,SYT9,PPFIA1,NLGN1,RPH3A,SLC6A9,CADPS,SNAP25,GAD2,CPLX2,SYT4,CACNA1A,CAMK2A,SYT6,P2RX7,HRH3,NRXN1,NRXN2,PNKD,SNCAIP,RIMS4,RIMS3,SYTL2,BLOC1S6,SYT15" GO: Biological Process GO:0007269 neurotransmitter secretion 2.10E-07 1.38E-03 1.22E-05 1.15E-04 25 163 "ASIC1,SYT9,PPFIA1,NLGN1,RPH3A,SLC6A9,CADPS,SNAP25,GAD2,CPLX2,SYT4,CACNA1A,CAMK2A,SYT6,P2RX7,HRH3,NRXN1,NRXN2,PNKD,SNCAIP,RIMS4,RIMS3,SYTL2,BLOC1S6,SYT15" GO: Biological Process GO:0010769 regulation of cell morphogenesis involved in differentiation 2.11E-07 1.38E-03 1.22E-05 1.15E-04 42 374 "MAG,MAPT,ACHE,MBP,DRAXIN,SEMA6A,SEMA6C,NLGN1,LRRC4C,SHTN1,MT3,SLIT1,CAPRIN2,TNIK,SPART,CLASP2,PHLDB1,ARHGEF7,SEMA4A,CNTN2,CACNA1A,TCF7L2,GRIN1,OMG,TGFBR3,CDC42,TNR,CHRNB2,NLGN3,SEMA5B,PLXNB3,POU3F2,LRP8,RGMA,PTPRD,PTPRO,PTPRZ1,DNM2,DSCAM,RTN4,L1CAM,RET" GO: Biological Process GO:0061337 cardiac conduction 2.23E-07 1.47E-03 1.29E-05 1.20E-04 22 131 "KCNIP2,RYR1,AGT,SCN4B,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,FXYD6,NPPA,CACNB2,KCND3,KCNJ4,KCNJ11,KCNK1,ABCC9,CACNG7" GO: Biological Process GO:0007158 neuron cell-cell adhesion 2.29E-07 1.50E-03 1.31E-05 1.22E-04 8 16 "NLGN4X,NLGN1,ASTN1,TNR,NLGN3,NRXN1,NRXN2,RET" GO: Biological Process GO:0010001 glial cell differentiation 2.35E-07 1.54E-03 1.33E-05 1.24E-04 29 210 "MAG,AGT,SOX6,SLC8A3,MT3,ASCL1,DLL3,SOX5,SOX10,NKX6-2,DNER,GFAP,NKX2-2,MYRF,CNTN2,TCF7L2,OMG,PAX6,GPR37L1,NLGN3,SERPINE2,POU3F2,TENM4,HES5,PTPRZ1,KCNJ10,OLIG1,RTN4,OLIG2" GO: Biological Process GO:0021779 oligodendrocyte cell fate commitment 2.51E-07 1.65E-03 1.38E-05 1.30E-04 5 5 "SOX6,ASCL1,NKX2-2,PAX6,OLIG2" GO: Biological Process GO:0021778 oligodendrocyte cell fate specification 2.51E-07 1.65E-03 1.38E-05 1.30E-04 5 5 "SOX6,ASCL1,NKX2-2,PAX6,OLIG2" GO: Biological Process GO:0021780 glial cell fate specification 2.51E-07 1.65E-03 1.38E-05 1.30E-04 5 5 "SOX6,ASCL1,NKX2-2,PAX6,OLIG2" GO: Biological Process GO:0008361 regulation of cell size 2.55E-07 1.67E-03 1.39E-05 1.31E-04 28 199 "MAPT,DRAXIN,SEMA6A,SEMA6C,ANXA7,SHTN1,AQP4,ARHGAP5,MT3,SLIT1,ATP2B2,WDTC1,RAP1GAP2,SPART,CLASP2,SEMA4A,OMG,P2RX7,TNR,SEMA5B,VAV2,RGMA,KCNMA1,DNM2,DSCAM,RTN4,L1CAM,RET" GO: Biological Process GO:0097480 establishment of synaptic vesicle localization 2.94E-07 1.93E-03 1.58E-05 1.48E-04 22 133 "SYT9,FGF14,AMPH,CNIH2,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,SYT4,CACNA1A,SYT6,P2RX7,PACSIN1,RIMS4,RIMS3,SYTL2,BLOC1S6,DNM2,SYT15" GO: Biological Process GO:0048489 synaptic vesicle transport 2.94E-07 1.93E-03 1.58E-05 1.48E-04 22 133 "SYT9,FGF14,AMPH,CNIH2,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,SYT4,CACNA1A,SYT6,P2RX7,PACSIN1,RIMS4,RIMS3,SYTL2,BLOC1S6,DNM2,SYT15" GO: Biological Process GO:0022037 metencephalon development 3.15E-07 2.07E-03 1.68E-05 1.57E-04 21 123 "ABAT,CEND1,NLGN4X,ASCL1,ATP2B2,GART,NEUROD1,CDK5R2,CACNA1A,HAP1,PTBP2,GRIN1,SEZ6L,HNRNPK,SERPINE2,NRXN1,CNTN1,PROX1,KCNC1,RFX4,SEZ6" GO: Biological Process GO:0032940 secretion by cell 3.34E-07 2.19E-03 1.77E-05 1.65E-04 89 1090 "RABEPK,SERPINA3,ABAT,ASIC1,ACHE,SYT9,LGR4,ACTN2,WLS,ADORA1,ADORA3,AGT,PLA2G6,FGR,ANK1,PPFIA1,APBB1,GPAM,SYBU,NLGN1,SLC1A2,SLC1A6,RPH3A,SLC1A7,MADD,SLC6A9,CADPS,PDE8B,SCG3,LGI3,SNAP25,GABBR1,ILDR2,GAD2,CPLX2,NCAM1,CLASP2,NEUROD1,ARHGEF7,ABCC8,GLS,VAMP1,SYT4,GNAS,CDK5R2,CACNA1A,CACNA1E,TCF7L2,CLEC9A,HAP1,CAMK2A,CAMK2G,SYT6,BRSK2,ATP13A2,TF,CCKBR,LEFTY2,P2RX7,PAX6,HRH3,ZNF384,PDE1C,PDE3B,HMGB1,CHGA,CHRNB2,SERPINE2,CADM1,NRXN1,NRXN2,PIK3CD,P2RY12,PNKD,SNCAIP,PPP3CB,RIMS4,RBPJ,PRKCZ,RIMS3,SYTL2,PTAFR,BLOC1S6,KCNA2,KCNJ11,C12orf4,RTN4,SYT15,SIDT2" GO: Biological Process GO:1903530 regulation of secretion by cell 3.49E-07 2.29E-03 1.83E-05 1.71E-04 67 744 "ABAT,ASIC1,ACHE,SYT9,LGR4,WLS,ADORA1,ADORA3,AGT,PLA2G6,FGR,APBB1,GPAM,SYBU,NLGN1,RPH3A,MADD,CADPS,PDE8B,LGI3,SNAP25,GABBR1,CPLX2,NCAM1,CLASP2,NEUROD1,ARHGEF7,ABCC8,SYT4,GNAS,CDK5R2,CACNA1A,CACNA1E,TCF7L2,CLEC9A,HAP1,CAMK2A,SYT6,BRSK2,ATP13A2,CCKBR,P2RX7,PAX6,HRH3,ZNF384,PDE1C,PDE3B,HMGB1,CHGA,CHRNB2,CADM1,NRXN1,P2RY12,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCZ,RIMS3,SYTL2,PTAFR,KCNA2,KCNJ11,C12orf4,RTN4,SYT15,SIDT2" GO: Biological Process GO:0051240 positive regulation of multicellular organismal process 6.45E-07 4.23E-03 3.36E-05 3.14E-04 119 1610 "MAG,ABAT,MAPT,ACHE,LGR4,SYNDIG1,F3,SLITRK1,ADORA3,AGT,LRRTM4,FGF1,PLA2G6,LRRC7,SEMA6A,FGR,FOXG1,SOX6,APBB1,GPAM,SLITRK3,NLGN1,SHTN1,CLSTN1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SCN3B,SOX5,SOX10,NKX6-2,ADGRB2,NAP1L2,NCAM1,CLASP2,STOX1,GFAP,NELL1,PHLDB1,NEUROD1,SYT4,NKX2-2,GNAS,NODAL,MYRF,MMD2,ADGRL3,GPM6B,ACSL6,VWC2,NPPA,TCF7L2,ZEB1,CLEC9A,TCF12,HAP1,DDR2,TF,PTPN5,USP2,P2RX7,NEURL1,PAX6,CDC42,TNR,PDE4B,ZMYND8,GPR37L1,HMGB1,LRTM2,CHGA,HNRNPK,NLGN3,SERPINE2,CADM1,NRXN1,NEGR1,FLRT1,PLXNB3,CNTN1,PACSIN1,NSD2,POU3F2,MED1,TENM4,RGS6,FEZ1,RBPJ,PRKCZ,MAPK8,PUM1,NOS1AP,PROX1,BRINP3,ZBTB16,SYTL2,PLPPR5,LRRTM3,PTAFR,PTCH1,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,KCNMA1,PEX5,DSCAM,RTN4,L1CAM,RET,FGFBP3,CBLN2,ELAVL4,OLIG2,TMEM100,SEZ6" GO: Biological Process GO:0040007 growth 6.58E-07 4.31E-03 3.40E-05 3.18E-04 88 1091 "MAPT,SLC25A25,SLITRK1,NLGN4X,DRAXIN,AGT,KIAA1109,FGF1,SEMA6A,FHL1,UNC79,FOXM1,SEMA6C,PI16,APBA2,APBB1,GPAM,DGKD,SHTN1,CLSTN1,SLC1A2,MT3,CGREF1,CSPG5,SLIT1,CAPRIN2,NRG3,WDTC1,SOX10,ADAM15,SPART,NCAM1,CLASP2,ERBIN,SYT4,SEMA4A,GNAS,GNG4,PSRC1,WWC1,CACNA1A,DDR1,NPPA,TCF7L2,DDR2,OMG,LEFTY2,TGFBR3,TLL2,CD81,MAEL,CDK11B,CDC42,TNR,DCLK1,LGI1,HNRNPK,HEPACAM,NLGN3,SERPINE2,CADM1,SEMA5B,FLRT1,FTO,POU3F2,MED1,TENM4,PPP3CB,RBPJ,PRKCZ,PROX1,KLK6,PTCH1,ITGAV,PTHLH,RGMA,MAGI2,KCNK2,PCDH15,PEX5,DNM2,DSCAM,RTN4,PAK5,L1CAM,VANGL2,SLC4A10,RASGRP2" GO: Biological Process GO:0099531 presynaptic process involved in chemical synaptic transmission 6.67E-07 4.38E-03 3.42E-05 3.20E-04 25 173 "ASIC1,SYT9,PPFIA1,NLGN1,RPH3A,SLC6A9,CADPS,SNAP25,GAD2,CPLX2,SYT4,CACNA1A,CAMK2A,SYT6,P2RX7,HRH3,NRXN1,NRXN2,PNKD,SNCAIP,RIMS4,RIMS3,SYTL2,BLOC1S6,SYT15" GO: Biological Process GO:0016049 cell growth 6.91E-07 4.53E-03 3.49E-05 3.27E-04 54 562 "MAPT,DRAXIN,AGT,KIAA1109,SEMA6A,FHL1,FOXM1,SEMA6C,PI16,APBB1,DGKD,SHTN1,CLSTN1,MT3,CGREF1,SLIT1,CAPRIN2,NRG3,ADAM15,SPART,CLASP2,ERBIN,SYT4,SEMA4A,GNG4,PSRC1,CACNA1A,DDR1,NPPA,OMG,LEFTY2,TGFBR3,CD81,CDK11B,CDC42,TNR,DCLK1,LGI1,HNRNPK,NLGN3,SERPINE2,CADM1,SEMA5B,FLRT1,PPP3CB,PRKCZ,ITGAV,RGMA,DNM2,DSCAM,RTN4,PAK5,L1CAM,RASGRP2" GO: Biological Process GO:0051963 regulation of synapse assembly 6.92E-07 4.54E-03 3.49E-05 3.27E-04 17 88 "SYNDIG1,SLITRK1,LRRTM4,SLITRK3,NLGN1,CLSTN1,SLIT1,ADGRB2,ADGRL3,GRIN1,LRTM2,CHRNB2,NLGN3,NRXN1,FLRT1,LRRTM3,CBLN2" GO: Biological Process GO:0051050 positive regulation of transport 7.26E-07 4.76E-03 3.64E-05 3.41E-04 86 1061 "ABAT,ACHE,SYT9,ACTN2,WLS,ADCYAP1R1,ADORA1,ADORA3,FCGR1A,AGT,SCN4B,PLA2G6,FGF14,FGR,FHL1,ELMOD1,SGIP1,ANK2,ANK3,APBB1,SORBS1,NLGN1,SLC1A2,CADPS,ASPH,SNAP25,ATP2B2,GABBR1,SCN3B,MYBPC1,AHCYL1,CLASP2,MLC1,ARHGEF7,ABCC8,GNAS,NODAL,CDK5R2,ACSL6,NPPA,CACNB2,TCF7L2,CLEC9A,GPR26,HAP1,AZIN2,CAMK2A,ATP13A2,TF,CCKBR,PTPN5,P2RX7,PAX6,CDC42,ZNF384,PIRT,HMGB1,CHRM1,TUB,CHRNB2,HNRNPK,HPCA,NLGN3,CADM1,CNTN1,P2RY12,MED1,PPP3CB,CALY,PRKCZ,MAPK8,NOS1AP,SYTL2,SIRPA,PTAFR,PTCH1,ITGAV,MAGI2,KCNC1,KCNJ11,KCNN3,DNM2,DPP6,RAP1GAP,RTN4,SH3GLB1" GO: Biological Process GO:0048588 developmental cell growth 7.66E-07 5.02E-03 3.80E-05 3.56E-04 29 222 "MAPT,DRAXIN,AGT,SEMA6A,SEMA6C,PI16,SHTN1,MT3,SLIT1,SPART,CLASP2,SYT4,SEMA4A,DDR1,NPPA,OMG,TNR,DCLK1,HNRNPK,NLGN3,SEMA5B,FLRT1,PPP3CB,PRKCZ,RGMA,DNM2,DSCAM,RTN4,L1CAM" GO: Biological Process GO:0045597 positive regulation of cell differentiation 7.83E-07 5.14E-03 3.86E-05 3.62E-04 80 966 "MAG,MAPT,ACHE,AGT,LRRC7,SEMA6A,FOXG1,SOX6,APBB1,APC,NLGN1,SHTN1,MSR1,ASCL1,DLL3,CAPRIN2,BRINP2,FYN,SOX5,SOX10,NKX6-2,NAP1L2,LMO3,GFAP,NELL1,NEUROD1,ARHGEF7,SYT4,NKX2-2,GNAS,MMD2,ACSL6,VWC2,TCF7L2,ZEB1,TCF12,HAP1,DDR2,TF,PTPN5,NEURL1,PAX6,CDC42,ZMYND8,FNDC5,HMGB1,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,MED1,TENM4,RGS6,FEZ1,RBPJ,PRKCZ,PROX1,BRINP3,ZBTB16,PLPPR5,PTCH1,LRP8,RGMA,MAGI2,BLOC1S6,PTPRD,PTPRZ1,CCDC3,DNM2,DSCAM,RTN4,L1CAM,RET,ELAVL4,OLIG2,TMEM100,SEZ6" GO: Biological Process GO:0021537 telencephalon development 8.03E-07 5.26E-03 3.93E-05 3.68E-04 32 260 "ATAT1,FOXG1,BCAN,TACC2,SLC1A2,SLC8A3,ASCL1,SLIT1,NRG3,SALL3,GART,KIRREL3,NEUROD1,DCLK2,CDK5R2,CNTN2,NRGN,GRIN1,PAX6,TNR,ADGRG1,HNRNPK,POU3F2,HES5,PROX1,LRP8,KCNA1,PTPRZ1,PEX5,RTN4,CRTAC1,RFX4" GO: Biological Process GO:0019226 transmission of nerve impulse 8.99E-07 5.90E-03 4.37E-05 4.09E-04 16 80 "AGT,SCN3A,ANK3,NFASC,CACNA1A,CACNA1E,GRIA1,GRIK2,GPR88,TNR,KCNA1,KCNA2,KCNMA1,KCNQ2,DPP6,CACNG7" GO: Biological Process GO:0021953 central nervous system neuron differentiation 9.56E-07 6.27E-03 4.61E-05 4.32E-04 27 200 "CEND1,DRAXIN,FOXG1,ASCL1,SLIT1,ATP2B2,SOX1,SOX5,NKX6-2,SALL3,DCLK2,NKX2-2,UNC5D,CNTN2,CACNA1A,PAX6,DCLK1,CHRNB2,NRXN1,POU3F4,CHD5,HES5,PROX1,PTCH1,PEX5,SLC4A10,OLIG2" GO: Biological Process GO:0051656 establishment of organelle localization 9.80E-07 6.42E-03 4.69E-05 4.39E-04 45 438 "MAPT,SYT9,EYA1,ADORA3,FGF14,FGR,AMPH,CDC42BPA,CNIH2,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SLIT1,SNAP25,ATM,KIF1B,CPLX2,CLASP2,SYT4,PSRC1,CACNA1A,HAP1,SYT6,NUMA1,GRIA1,P2RX7,PAX6,CDC42,CHGA,PIK3CD,PACSIN1,FEZ1,RIMS4,FMN2,PRKCZ,RIMS3,SYTL2,SPIRE1,CNIH3,BLOC1S6,DNM2,C12orf4,SYT15" GO: Biological Process GO:0042552 myelination 1.02E-06 6.69E-03 4.85E-05 4.54E-04 20 121 "MAG,MBP,RXRG,ANK2,SLC8A3,FYN,NKX6-2,NFASC,ACSBG1,MYRF,CNTN2,TCF7L2,TF,OMG,POU3F2,TENM4,HES5,KLK6,KCNJ10,OLIG2" GO: Biological Process GO:0021549 cerebellum development 1.10E-06 7.18E-03 5.16E-05 4.84E-04 19 111 "ABAT,CEND1,NLGN4X,ATP2B2,GART,NEUROD1,CDK5R2,CACNA1A,HAP1,PTBP2,SEZ6L,HNRNPK,SERPINE2,NRXN1,CNTN1,PROX1,KCNC1,RFX4,SEZ6" GO: Biological Process GO:0050771 negative regulation of axonogenesis 1.14E-06 7.46E-03 5.33E-05 4.99E-04 15 72 "MAG,MBP,DRAXIN,SEMA6A,SEMA6C,MT3,SLIT1,SPART,SEMA4A,OMG,TNR,SEMA5B,RGMA,PTPRO,RTN4" GO: Biological Process GO:0007411 axon guidance 1.27E-06 8.34E-03 5.92E-05 5.54E-04 30 240 "DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,SLIT1,FYN,USP33,NFASC,NCAM1,SEMA4A,ROBO3,UNC5D,CNTN2,PAX6,TNR,LGI1,NRXN1,SEMA5B,PLXNB3,CRMP1,FEZ2,FEZ1,DPYSL5,PTPRO,DSCAM,L1CAM,VANGL2,EFNA3" GO: Biological Process GO:0008366 axon ensheathment 1.33E-06 8.74E-03 6.11E-05 5.72E-04 20 123 "MAG,MBP,RXRG,ANK2,SLC8A3,FYN,NKX6-2,NFASC,ACSBG1,MYRF,CNTN2,TCF7L2,TF,OMG,POU3F2,TENM4,HES5,KLK6,KCNJ10,OLIG2" GO: Biological Process GO:0007272 ensheathment of neurons 1.33E-06 8.74E-03 6.11E-05 5.72E-04 20 123 "MAG,MBP,RXRG,ANK2,SLC8A3,FYN,NKX6-2,NFASC,ACSBG1,MYRF,CNTN2,TCF7L2,TF,OMG,POU3F2,TENM4,HES5,KLK6,KCNJ10,OLIG2" GO: Biological Process GO:0097485 neuron projection guidance 1.39E-06 9.10E-03 6.32E-05 5.92E-04 30 241 "DRAXIN,SEMA6A,FOXG1,SEMA6C,ANK3,APBB1,SLIT1,FYN,USP33,NFASC,NCAM1,SEMA4A,ROBO3,UNC5D,CNTN2,PAX6,TNR,LGI1,NRXN1,SEMA5B,PLXNB3,CRMP1,FEZ2,FEZ1,DPYSL5,PTPRO,DSCAM,L1CAM,VANGL2,EFNA3" GO: Biological Process GO:0051648 vesicle localization 1.44E-06 9.47E-03 6.53E-05 6.12E-04 32 267 "SYT9,SYNDIG1,FGF14,AMPH,CNIH2,ITSN1,SH3GL2,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,CLASP2,SYT4,CACNA1A,TCF7L2,HAP1,SYT6,GRIA1,P2RX7,NLGN3,NRXN1,PACSIN1,RIMS4,PRKCZ,RIMS3,SYTL2,CNIH3,MAGI2,BLOC1S6,DNM2,SYT15" GO: Biological Process GO:0008016 regulation of heart contraction 1.52E-06 9.93E-03 6.80E-05 6.37E-04 30 242 "MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,CACNA1E,NPPA,CACNB2,SPX,PDE4B,CHGA,NOS1AP,KCND3,KCNJ4,KCNJ11,KCNK1,ABCC9,CACNG7" GO: Biological Process GO:0019233 sensory perception of pain 1.54E-06 1.01E-02 6.86E-05 6.42E-04 21 135 "ADORA1,SCN3A,FYN,SCN3B,NCAM1,CACNA1A,CACNA1E,GRIN1,GRM3,CCKBR,SPX,P2RX7,ASIC3,CHRNB2,PTAFR,KCNA1,KCNA2,KCNJ10,DLG2,RTN4,TMEM100" GO: Biological Process GO:0022604 regulation of cell morphogenesis 1.72E-06 1.13E-02 7.63E-05 7.15E-04 56 609 "MAG,EPS8,MAPT,ACHE,MBP,CDC7,ERMN,DRAXIN,SEMA6A,FGR,SEMA6C,ANXA7,GAS7,NLGN1,LRRC4C,SHTN1,MT3,SLIT1,CAPRIN2,FYN,TNIK,SPART,CLASP2,PHLDB1,ARHGEF7,SYT4,SEMA4A,CNTN2,CACNA1A,TCF7L2,HAP1,GRIN1,OMG,TGFBR3,CDC42,TNR,CHRNB2,HNRNPK,NLGN3,SEMA5B,PLXNB3,POU3F2,LRP8,RGMA,PTPRD,PTPRO,PTPRZ1,WIPF2,DNM2,DSCAM,RTN4,L1CAM,RET,PLEKHO1,EPB41,EPB41L2" GO: Biological Process GO:0048640 negative regulation of developmental growth 1.77E-06 1.16E-02 7.79E-05 7.29E-04 18 104 "DRAXIN,SEMA6A,SEMA6C,PI16,MT3,SLIT1,SPART,SEMA4A,GNAS,WWC1,TCF7L2,TLL2,TNR,SEMA5B,PTCH1,RGMA,KCNK2,RTN4" GO: Biological Process GO:0051046 regulation of secretion 2.24E-06 1.47E-02 9.81E-05 9.19E-04 68 800 "ABAT,ASIC1,ACHE,SYT9,LGR4,WLS,ADORA1,ADORA3,AGT,PLA2G6,FGR,APBB1,GPAM,SYBU,NLGN1,RPH3A,MADD,CADPS,PDE8B,LGI3,SNAP25,GABBR1,CPLX2,NCAM1,CLASP2,NEUROD1,ARHGEF7,ABCC8,SYT4,GNAS,CDK5R2,CACNA1A,CACNA1E,TCF7L2,CLEC9A,HAP1,CAMK2A,SYT6,BRSK2,ATP13A2,CCKBR,SPX,P2RX7,PAX6,HRH3,ZNF384,PDE1C,PDE3B,HMGB1,CHGA,CHRNB2,CADM1,NRXN1,P2RY12,PNKD,SNCAIP,PPP3CB,RIMS4,PRKCZ,RIMS3,SYTL2,PTAFR,KCNA2,KCNJ11,C12orf4,RTN4,SYT15,SIDT2" GO: Biological Process GO:0031346 positive regulation of cell projection organization 2.27E-06 1.49E-02 9.88E-05 9.25E-04 39 367 "MAPT,ACHE,LRRC7,APBB1,APC,NLGN1,SHTN1,CAPRIN2,FYN,ARHGEF7,SYT4,GPM6A,ACSL6,HAP1,PTPN5,P2RX7,NEURL1,CDC42,ZMYND8,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,FEZ1,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DNM2,DSCAM,L1CAM,RET,ELAVL4,SEZ6" GO: Biological Process GO:0010976 positive regulation of neuron projection development 2.32E-06 1.52E-02 9.99E-05 9.36E-04 33 286 "MAPT,ACHE,LRRC7,APBB1,NLGN1,SHTN1,CAPRIN2,FYN,SYT4,ACSL6,HAP1,PTPN5,NEURL1,ZMYND8,HNRNPK,NLGN3,SERPINE2,NEGR1,PLXNB3,CNTN1,PACSIN1,FEZ1,PLPPR5,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,DSCAM,L1CAM,RET,ELAVL4,SEZ6" GO: Biological Process GO:0032291 axon ensheathment in central nervous system 2.44E-06 1.60E-02 1.04E-04 9.74E-04 7 15 "NKX6-2,MYRF,CNTN2,OMG,TENM4,HES5,KCNJ10" GO: Biological Process GO:0022010 central nervous system myelination 2.44E-06 1.60E-02 1.04E-04 9.74E-04 7 15 "NKX6-2,MYRF,CNTN2,OMG,TENM4,HES5,KCNJ10" GO: Biological Process GO:0031644 regulation of neurological system process 2.47E-06 1.62E-02 1.04E-04 9.78E-04 16 86 "MAG,ADORA1,AGT,NCAM1,MYRF,GRM3,TF,CCKBR,SPX,TNR,TENM4,PTAFR,KCNJ10,RTN4,FGFBP3,TMEM100" GO: Biological Process GO:1903779 regulation of cardiac conduction 2.48E-06 1.63E-02 1.04E-04 9.78E-04 14 67 "RYR1,AGT,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,AHCYL1,FXYD6,NPPA,KCNJ11,ABCC9" GO: Biological Process GO:0016358 dendrite development 3.47E-06 2.28E-02 1.45E-04 1.36E-03 29 239 "MAP6,ACHE,NLGN1,CAPRIN2,FYN,TNIK,CACNA1A,CAMK2A,GRIN1,NEURL1,DCLK1,RBFOX2,ZMYND8,CHRNB2,HNRNPK,NLGN3,FLRT1,PACSIN1,FAT3,CTNND2,MAPK8,LRP8,PTPRD,PTPRZ1,ABI1,DSCAM,ABI2,ELAVL4,SEZ6" GO: Biological Process GO:0048813 dendrite morphogenesis 3.54E-06 2.32E-02 1.47E-04 1.37E-03 21 142 "MAP6,ACHE,NLGN1,CAPRIN2,FYN,TNIK,CACNA1A,CAMK2A,GRIN1,DCLK1,RBFOX2,CHRNB2,NLGN3,CTNND2,MAPK8,LRP8,PTPRD,PTPRZ1,ABI1,DSCAM,ELAVL4" GO: Biological Process GO:0051965 positive regulation of synapse assembly 3.59E-06 2.36E-02 1.48E-04 1.39E-03 14 69 "SYNDIG1,SLITRK1,LRRTM4,SLITRK3,NLGN1,CLSTN1,ADGRB2,ADGRL3,LRTM2,NLGN3,NRXN1,FLRT1,LRRTM3,CBLN2" GO: Biological Process GO:1990138 neuron projection extension 4.27E-06 2.80E-02 1.75E-04 1.64E-03 23 167 "MAPT,DRAXIN,SEMA6A,SEMA6C,SHTN1,MT3,SLIT1,CLASP2,SYT4,SEMA4A,DDR1,TNR,DCLK1,HNRNPK,NLGN3,SEMA5B,FLRT1,PPP3CB,PRKCZ,DNM2,DSCAM,RTN4,L1CAM" GO: Biological Process GO:0051130 positive regulation of cellular component organization 4.79E-06 3.14E-02 1.95E-04 1.83E-03 95 1263 "MAPT,ACHE,SYNDIG1,ACTN2,ATAT1,CLIP1,SLITRK1,FCGR1A,AGT,LRRTM4,PLA2G6,LRRC7,ELMOD1,SFPQ,SGIP1,ANK1,ANK3,PPM1E,APBB1,APC,SLITRK3,SORBS1,NLGN1,SHTN1,CLSTN1,MIER1,CAPRIN2,SLN,ATM,EIF4G3,FYN,PALLD,MYBPC1,ADGRB2,NAP1L2,CLASP2,PHLDB1,ARHGEF7,SYT4,DDHD2,PSRC1,ADGRL3,GPM6A,ACSL6,TCF7L2,GPR26,HAP1,DDR2,TF,PTPN5,P2RX7,NEURL1,CDC42,ZMYND8,LRTM2,TUB,HNRNPK,HPCA,NLGN3,SERPINE2,NRXN1,NEGR1,FLRT1,PLXNB3,CNTN1,PACSIN1,CHD1L,FEZ1,FMN2,CALY,MAPK8,PROX1,SPIRE1,PLPPR5,LRRTM3,SIRPA,ITGAV,LRP8,RGMA,MAGI2,PTPRD,PTPRZ1,KCNN3,WIPF2,DNM2,DPP6,RAP1GAP,DSCAM,L1CAM,RET,SH3GLB1,ABI2,CBLN2,ELAVL4,SEZ6" GO: Biological Process GO:0014013 regulation of gliogenesis 5.29E-06 3.47E-02 2.14E-04 2.01E-03 18 112 "MAG,DLL3,ZCCHC24,SOX10,NKX6-2,GFAP,NKX2-2,CNTN2,TCF7L2,TF,GPR37L1,SERPINE2,P2RY12,TENM4,HES5,PTPRZ1,RTN4,OLIG2" GO: Biological Process GO:0006897 endocytosis 5.85E-06 3.84E-02 2.36E-04 2.21E-03 58 665 "RABEPK,ACHE,LDLRAD3,CDC7,ADORA1,SNX30,FCGR1A,FCGR1B,SNX32,PLA2G6,FGR,AMPH,SGIP1,ITSN1,SH3GL2,DGKD,NLGN1,MSR1,ARFGAP1,FYN,USP33,DNER,MLC1,CNTN2,CLEC9A,GRIA1,GRIA2,TF,OLR1,PTPN5,P2RX7,CD81,CDC42,HMGB1,TMPRSS5,TUB,HNRNPK,NLGN3,ZFYVE9,HPR,VAV2,PACSIN1,CALY,RAB39A,PRKCG,PLPP4,MASP1,SIRPA,DNAJC6,ITGAV,ELMO1,LRP8,MAGI2,WIPF2,RAB5B,DNM2,RAP1GAP,ABI1" GO: Biological Process GO:2001259 positive regulation of cation channel activity 5.96E-06 3.91E-02 2.37E-04 2.22E-03 11 45 "ACTN2,FGF14,ANK2,ANK3,ASPH,NPPA,CACNB2,HAP1,PIRT,NOS1AP,KCNJ11" GO: Biological Process GO:0008038 neuron recognition 5.97E-06 3.91E-02 2.37E-04 2.22E-03 10 37 "DSCAML1,FOXG1,ROBO3,CNTN2,OPCML,PTPRZ1,NTM,DSCAM,RTN4,CRTAC1" GO: Biological Process GO:0007613 memory 6.78E-06 4.45E-02 2.68E-04 2.51E-03 19 125 "ASIC1,PLA2G6,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,ATP1A3,GRIA1,GRIN1,KCNK10,HRH3,CHRNB2,PPP3CB,PRKCZ,KCNK2,RASGRF1,PAK5,RCAN2" GO: Biological Process GO:0090075 relaxation of muscle 6.82E-06 4.47E-02 2.68E-04 2.51E-03 9 30 "MRVI1,ADORA1,SLN,ATP1A2,CAMK2G,GUCY1A1,PDE4B,CHGA,KCNMA1" GO: Biological Process GO:0048638 regulation of developmental growth 7.32E-06 4.80E-02 2.86E-04 2.68E-03 36 343 "MAPT,DRAXIN,AGT,SEMA6A,SEMA6C,PI16,GPAM,SHTN1,MT3,SLIT1,SPART,NCAM1,CLASP2,SYT4,SEMA4A,GNAS,WWC1,TCF7L2,OMG,TLL2,MAEL,TNR,HNRNPK,SEMA5B,FTO,POU3F2,RBPJ,PROX1,PTCH1,RGMA,KCNK2,PEX5,DNM2,DSCAM,RTN4,L1CAM" GO: Biological Process GO:0014003 oligodendrocyte development 7.75E-06 5.09E-02 3.01E-04 2.82E-03 10 38 "ASCL1,NKX6-2,NKX2-2,MYRF,CNTN2,TCF7L2,OMG,TENM4,HES5,KCNJ10" GO: Biological Process GO:0060047 heart contraction 8.09E-06 5.31E-02 3.12E-04 2.92E-03 31 276 "MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,CACNA1E,NPPA,CACNB2,SPX,CDC42,PDE4B,CHGA,NOS1AP,KCND3,KCNJ4,KCNJ11,KCNK1,ABCC9,CACNG7" GO: Biological Process GO:0097120 receptor localization to synapse 8.12E-06 5.33E-02 3.12E-04 2.92E-03 6 12 "CNIH2,NLGN1,NRXN1,ANKS1B,DLG2,DLG3" GO: Biological Process GO:0051093 negative regulation of developmental process 8.75E-06 5.74E-02 3.32E-04 3.11E-03 73 914 "MAG,MBP,CEND1,ADGRV1,DRAXIN,AGT,DISP3,SEMA6A,FOXG1,FOXM1,SEMA6C,PI16,APBB1,APC,NLGN1,MT3,ASCL1,SLIT1,DLL3,NRG3,NKX6-2,ADGRB2,RAP1GAP2,SPART,CLASP2,GFAP,C1QC,NKX2-2,SEMA4A,GNAS,NODAL,CNTN2,WWC1,TCF7L2,ZEB1,OMG,TGFBR3,USP2,TIE1,TLL2,PAX6,TNR,PDE3B,GPR37L1,ADGRG1,HMGB1,HNRNPK,NLGN3,SEMA5B,TJP2,P2RY12,FAT3,MED1,CRMP1,RBPJ,PRKACB,CMTM5,HES5,ZBTB16,PTCH1,ITGAV,PTHLH,RGMA,PTPRO,PTPRZ1,NTM,KCNK2,FAM57B,RAP1GAP,RTN4,RFX4,OLIG2,SEZ6" GO: Biological Process GO:0010959 regulation of metal ion transport 8.76E-06 5.75E-02 3.32E-04 3.11E-03 38 374 "ACTN2,KCNIP2,ADCYAP1R1,ADORA1,AGT,SCN4B,PLA2G6,FGF14,FHL1,ANK2,ANK3,ASPH,SLN,ATP1A2,ATP2B2,SCN3B,CAB39,AHCYL1,JPH4,ABCC8,GNAS,NPPA,CACNB2,HAP1,CAMK2A,CAMK2G,P2RX7,PDE4B,SERPINE2,CNTN1,BEST1,P2RY12,NKAIN4,NOS1AP,KCNC1,NKAIN1,DNM2,DPP6" GO: Biological Process GO:0007009 plasma membrane organization 9.02E-06 5.92E-02 3.40E-04 3.19E-03 32 291 "ZFYVE27,ACTN2,CLIP1,GPR158,SGIP1,ANK1,ANK2,ANK3,PPFIA1,SORBS1,SCN3B,TNIK,NFASC,CLASP2,MYRF,ANO4,CACNB2,CRB1,P2RX7,ZDHHC22,TUB,TMEFF2,NRXN1,PACSIN1,PRKCZ,SYTL2,PTCH1,PID1,DNM2,DPP6,GOPC,SH3GLB1" GO: Biological Process GO:0060291 long-term synaptic potentiation 9.42E-06 6.18E-02 3.51E-04 3.29E-03 13 65 "NLGN1,SLC8A2,SLC8A3,SHANK2,SNAP25,GFAP,NRGN,PTPN5,TNR,HNRNPK,NLGN3,SERPINE2,PRKCZ" GO: Biological Process GO:0050885 neuromuscular process controlling balance 9.42E-06 6.18E-02 3.51E-04 3.29E-03 13 65 "PDE8B,ATP2B2,JPH4,NKX6-2,CAMTA1,CACNA1A,GPR88,TNR,RBFOX2,NRXN1,PCDH15,KCNMA1,USH1C" GO: Biological Process GO:0060627 regulation of vesicle-mediated transport 1.00E-05 6.56E-02 3.70E-04 3.47E-03 47 508 "SYT9,ACTN2,ADORA3,FCGR1A,PLA2G6,FGF14,FGR,SGIP1,CNIH2,SH3GL2,NLGN1,RPH3A,CADPS,LGI3,ARFGAP1,CPLX2,NCAM1,CLASP2,SYT4,CDK5R2,CACNA1A,HAP1,SYT6,ATP13A2,TF,PTPN5,HMGB1,TUB,HNRNPK,PACSIN1,RIMS4,CALY,PRKCG,RIMS3,SYTL2,SIRPA,PTAFR,DNAJC6,ITGAV,MAGI2,RABGAP1L,RAB5B,DNM2,C12orf4,RAP1GAP,GOPC,SYT15" GO: Biological Process GO:0003015 heart process 1.01E-05 6.60E-02 3.71E-04 3.48E-03 31 279 "MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,CACNA1E,NPPA,CACNB2,SPX,CDC42,PDE4B,CHGA,NOS1AP,KCND3,KCNJ4,KCNJ11,KCNK1,ABCC9,CACNG7" GO: Biological Process GO:0032535 regulation of cellular component size 1.05E-05 6.90E-02 3.86E-04 3.61E-03 38 377 "EPS8,MAPT,ACTN2,DRAXIN,SEMA6A,SEMA6C,ANXA7,SHTN1,AQP4,ARHGAP5,MT3,SLIT1,ATP2B2,WDTC1,RAP1GAP2,SPART,CLASP2,SEMA4A,CNTN2,ATP13A2,OMG,P2RX7,TNR,SEMA5B,VAV2,FMN2,SPIRE1,HP1BP3,RGMA,KCNMA1,WIPF2,DNM2,DSCAM,RTN4,L1CAM,RET,USH1C,ABI2" GO: Biological Process GO:0016192 vesicle-mediated transport 1.11E-05 7.30E-02 4.05E-04 3.80E-03 108 1514 "RABEPK,SERPINA3,ACHE,SYT9,RTN3,ACTN2,LDLRAD3,CDC7,ADORA1,SNX30,ADORA3,FCGR1A,FCGR1B,SNX32,PLA2G6,FGF14,FGR,AMPH,SGIP1,ANK1,ANK2,ANK3,CNIH2,ITSN1,SH3GL2,DGKD,NLGN1,RPH3A,MSR1,ARFGAP2,NSG2,CADPS,SCG3,LGI3,ARFGAP1,SNAP25,FYN,USP33,CPLX2,DNER,NCAM1,CLASP2,MLC1,VAMP1,SYT4,CDK5R2,CNTN2,GOLGB1,CACNA1A,CLEC9A,HAP1,CECR2,SYT6,BRSK2,GRIA1,GRIA2,ATP13A2,TF,OLR1,PTPN5,LEFTY2,MFSD2A,P2RX7,CD81,CDC42,HMGB1,TMPRSS5,CHGA,TUB,HNRNPK,NLGN3,ZFYVE9,NRXN1,PIK3CD,HPR,VAV2,PACSIN1,PPP3CB,RIMS4,FMN2,CALY,RAB39A,PRKCG,PLPP4,MASP1,RIMS3,SYTL2,SPIRE1,SIRPA,PTAFR,DNAJC6,ITGAV,ELMO1,CNIH3,LRP8,MAGI2,BLOC1S6,RABGAP1L,SNX27,KIF2A,WIPF2,RAB5B,DNM2,C12orf4,RAP1GAP,ABI1,GOPC,SYT15" GO: Biological Process GO:0061387 regulation of extent of cell growth 1.12E-05 7.34E-02 4.05E-04 3.80E-03 18 118 "MAPT,DRAXIN,SEMA6A,SEMA6C,SHTN1,MT3,SLIT1,SPART,CLASP2,SEMA4A,OMG,TNR,SEMA5B,RGMA,DNM2,DSCAM,RTN4,L1CAM" GO: Biological Process GO:0097104 postsynaptic membrane assembly 1.18E-05 7.76E-02 4.27E-04 4.00E-03 5 8 "NLGN1,NLGN3,NRXN1,NRXN2,MAGI2" GO: Biological Process GO:0044089 positive regulation of cellular component biogenesis 1.27E-05 8.35E-02 4.56E-04 4.27E-03 43 453 "MAPT,SYNDIG1,ATAT1,CLIP1,SLITRK1,AGT,LRRTM4,PPM1E,APC,SLITRK3,NLGN1,CLSTN1,ATM,PALLD,ADGRB2,CLASP2,PHLDB1,PSRC1,ADGRL3,GPM6A,HAP1,P2RX7,NEURL1,CDC42,ZMYND8,LRTM2,CHGA,NLGN3,NRXN1,FLRT1,CHD1L,FMN2,MAPK8,PROX1,SPIRE1,PLPPR5,LRRTM3,MAGI2,WIPF2,DNM2,SH3GLB1,ABI2,CBLN2" GO: Biological Process GO:0061024 membrane organization 1.31E-05 8.59E-02 4.67E-04 4.37E-03 83 1091 "RPL38,ZFYVE27,MBP,SYT9,ACTN2,KCNIP2,CLIP1,ADORA1,NLGN4X,FCGR1A,GPR158,LRRTM4,SGIP1,ANK1,ANK2,ANK3,CNIH2,PPFIA1,ANXA7,SORBS1,NLGN1,RPH3A,MT3,CCDC88A,RTP5,NSG2,SNAP25,SCN3B,TNIK,NEK6,NFASC,CLASP2,VAMP1,SYT4,MYRF,CNTN2,ANO4,CACNA1A,CACNB2,AZIN2,CAMK2A,SYT6,GRIA1,GRIK2,CRB1,P2RX7,TIE1,ZDHHC22,ATG4C,ZMYND8,TUB,TMEFF2,HPCA,NLGN3,NRXN1,NRXN2,PMP2,PACSIN1,CALY,RAB39A,PRKCZ,MAPK8,SYTL2,TOMM20,SIRPA,PTCH1,ELMO1,CNIH3,MAGI2,BLOC1S6,PTPRD,RABGAP1L,PEX5,DLG2,DLG3,PID1,DNM2,PARP11,DPP6,GOPC,NUP214,SYT15,SH3GLB1" GO: Biological Process GO:0090066 regulation of anatomical structure size 1.34E-05 8.75E-02 4.73E-04 4.43E-03 49 544 "EPS8,MAPT,ACTN2,MRVI1,ADORA1,DRAXIN,AGT,PLA2G6,SEMA6A,SEMA6C,ANXA7,SHTN1,AQP4,ARHGAP5,MT3,SLIT1,ATP1A2,ATP2B2,WDTC1,RAP1GAP2,SPART,CLASP2,SEMA4A,CNTN2,NPPA,ATP13A2,OMG,TGFBR3,P2RX7,GUCY1A1,TNR,CHGA,CHRM1,SEMA5B,VAV2,FMN2,SPIRE1,PTAFR,HP1BP3,RGMA,KCNMA1,WIPF2,DNM2,DSCAM,RTN4,L1CAM,RET,USH1C,ABI2" GO: Biological Process GO:0048505 regulation of timing of cell differentiation 1.45E-05 9.50E-02 5.11E-04 4.78E-03 6 13 "ASCL1,SOX5,NODAL,PAX6,SERPINE2,RBPJ" GO: Biological Process GO:0006814 sodium ion transport 1.49E-05 9.79E-02 5.24E-04 4.91E-03 26 218 "ASIC1,AGT,SCN3A,SCN4B,SCNN1D,FGF14,ASIC4,ANK3,SLC8A2,SLC8A3,ATP1A2,ATP1A3,SCN3B,AHCYL1,GNAS,P2RX7,ASIC3,SERPINE2,CNTN1,NKAIN4,KCNK1,NKAIN1,DNM2,SLC17A6,SLC6A15,SLC4A10" GO: Biological Process GO:0071709 membrane assembly 1.82E-05 1.19E-01 6.34E-04 5.94E-03 8 26 "NLGN4X,ANK3,NLGN1,NLGN3,NRXN1,NRXN2,MAGI2,PTPRD" GO: Biological Process GO:0060078 regulation of postsynaptic membrane potential 1.85E-05 1.21E-01 6.41E-04 6.00E-03 16 100 "ABAT,ADORA1,NLGN4X,SCN3A,SCN4B,FGF14,NLGN1,IGSF9B,SCN3B,GRIK2,GRIN1,ZMYND8,NLGN3,NRXN1,PRKCZ,SEZ6" GO: Biological Process GO:0032414 positive regulation of ion transmembrane transporter activity 1.86E-05 1.22E-01 6.42E-04 6.01E-03 14 79 "ACTN2,FGF14,ANK2,ANK3,ASPH,NPPA,CACNB2,HAP1,PIRT,NLGN3,NOS1AP,PTAFR,KCNJ11,DNM2" GO: Biological Process GO:0016079 synaptic vesicle exocytosis 2.03E-05 1.33E-01 6.97E-04 6.53E-03 15 90 "SYT9,NLGN1,RPH3A,CADPS,SNAP25,CPLX2,SYT4,CACNA1A,SYT6,P2RX7,RIMS4,RIMS3,SYTL2,BLOC1S6,SYT15" GO: Biological Process GO:0001709 cell fate determination 2.16E-05 1.41E-01 7.36E-04 6.89E-03 11 51 "DSCAML1,FOXG1,ASCL1,DLL3,NKX2-2,PAX6,CDC42,PRRX1,HES5,PROX1,PTCH1" GO: Biological Process GO:0040034 "regulation of development, heterochronic" 2.43E-05 1.60E-01 8.27E-04 7.74E-03 6 14 "ASCL1,SOX5,NODAL,PAX6,SERPINE2,RBPJ" GO: Biological Process GO:1903522 regulation of blood circulation 2.47E-05 1.62E-01 8.36E-04 7.83E-03 34 334 "MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,PLA2G6,ANK2,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,CACNA1E,NPPA,CACNB2,SPX,PDE4B,CHGA,CHRM1,NOS1AP,PTAFR,KCND3,KCNJ4,KCNJ11,KCNK1,KCNMA1,ABCC9,CACNG7" GO: Biological Process GO:0043268 positive regulation of potassium ion transport 2.54E-05 1.66E-01 8.48E-04 7.94E-03 10 43 "ACTN2,ADORA1,FHL1,ANK2,ABCC8,NPPA,NOS1AP,KCNC1,DNM2,DPP6" GO: Biological Process GO:0097091 synaptic vesicle clustering 2.56E-05 1.68E-01 8.48E-04 7.94E-03 5 9 "SYNDIG1,NLGN1,NLGN3,NRXN1,MAGI2" GO: Biological Process GO:0097105 presynaptic membrane assembly 2.56E-05 1.68E-01 8.48E-04 7.94E-03 5 9 "NLGN4X,NLGN1,NLGN3,NRXN1,PTPRD" GO: Biological Process GO:0048708 astrocyte differentiation 2.56E-05 1.68E-01 8.48E-04 7.94E-03 13 71 "MAG,AGT,SOX6,MT3,DLL3,GFAP,NKX2-2,CNTN2,PAX6,GPR37L1,SERPINE2,POU3F2,HES5" GO: Biological Process GO:0048168 regulation of neuronal synaptic plasticity 2.93E-05 1.92E-01 9.64E-04 9.03E-03 12 62 "AGT,BCAN,SLC8A2,NCDN,CNTN2,CAMK2A,GRIK2,GRIN1,SHISA7,NEURL1,KCNJ10,RASGRF1" GO: Biological Process GO:0035418 protein localization to synapse 3.32E-05 2.18E-01 1.09E-03 1.02E-02 8 28 "CNIH2,NLGN1,NLGN3,NRXN1,NRXN2,ANKS1B,DLG2,DLG3" GO: Biological Process GO:0098657 import into cell 3.80E-05 2.49E-01 1.24E-03 1.16E-02 11 54 "AGT,SLC2A5,SLC8A2,SLC8A3,SNAP25,ATP1A2,GFAP,GPM6B,TF,KCNJ10,SLC17A6" GO: Biological Process GO:0021781 glial cell fate commitment 3.89E-05 2.55E-01 1.26E-03 1.18E-02 6 15 "SOX6,ASCL1,NKX2-2,PAX6,HES5,OLIG2" GO: Biological Process GO:0045596 negative regulation of cell differentiation 3.99E-05 2.62E-01 1.29E-03 1.21E-02 57 694 "MAG,MBP,ADGRV1,DRAXIN,DISP3,SEMA6A,FOXG1,SEMA6C,PI16,APBB1,NLGN1,MT3,ASCL1,SLIT1,DLL3,NRG3,NKX6-2,RAP1GAP2,SPART,GFAP,C1QC,NKX2-2,SEMA4A,NODAL,CNTN2,TCF7L2,ZEB1,OMG,TGFBR3,PAX6,TNR,GPR37L1,ADGRG1,HMGB1,NLGN3,SEMA5B,TJP2,P2RY12,FAT3,MED1,CRMP1,RBPJ,CMTM5,HES5,ZBTB16,PTCH1,ITGAV,PTHLH,RGMA,PTPRO,PTPRZ1,NTM,FAM57B,RAP1GAP,RTN4,OLIG2,SEZ6" GO: Biological Process GO:0001558 regulation of cell growth 4.01E-05 2.63E-01 1.29E-03 1.21E-02 41 445 "MAPT,DRAXIN,AGT,KIAA1109,SEMA6A,FHL1,FOXM1,SEMA6C,PI16,APBB1,SHTN1,CLSTN1,MT3,CGREF1,SLIT1,CAPRIN2,NRG3,ADAM15,SPART,CLASP2,SYT4,SEMA4A,GNG4,PSRC1,DDR1,NPPA,OMG,CD81,CDK11B,CDC42,TNR,LGI1,HNRNPK,SERPINE2,SEMA5B,RGMA,DNM2,DSCAM,RTN4,L1CAM,RASGRP2" GO: Biological Process GO:0051241 negative regulation of multicellular organismal process 4.19E-05 2.75E-01 1.34E-03 1.26E-02 83 1127 "MAG,ABAT,MBP,LGR4,CEND1,MRVI1,NDRG2,ADORA1,DRAXIN,AGT,DISP3,SEMA6A,FOXG1,SEMA6C,PI16,APBB1,APC,NLGN1,AQP4,MADD,MT3,ASCL1,SLIT1,DLL3,ATP1A2,NRG3,NKX6-2,ADGRB2,RAP1GAP2,SPART,ERBIN,GFAP,C1QC,NKX2-2,SEMA4A,GNAS,NODAL,CNTN2,WWC1,NPPA,TCF7L2,OMG,SPX,TGFBR3,USP2,P2RX7,TIE1,GUCY1A1,TLL2,PAX6,TNR,PTGDR2,PDE3B,PDE4B,GPR37L1,ADGRG1,HMGB1,CHGA,HNRNPK,NLGN3,SERPINE2,SEMA5B,TJP2,FAT3,MED1,CRMP1,RBPJ,PRKACB,HES5,ZBTB16,PTCH1,PTHLH,RGMA,PTPRO,PTPRZ1,NTM,KCNK2,KCNMA1,RAP1GAP,RTN4,RFX4,OLIG2,SEZ6" GO: Biological Process GO:0010771 negative regulation of cell morphogenesis involved in differentiation 4.28E-05 2.80E-01 1.36E-03 1.28E-02 18 130 "MAG,MBP,DRAXIN,SEMA6A,SEMA6C,NLGN1,MT3,SLIT1,SPART,SEMA4A,OMG,TGFBR3,TNR,NLGN3,SEMA5B,RGMA,PTPRO,RTN4" GO: Biological Process GO:1901841 regulation of high voltage-gated calcium channel activity 4.92E-05 3.23E-01 1.56E-03 1.46E-02 5 10 "FGF14,NPPA,CACNB2,PDE4B,NOS1AP" GO: Biological Process GO:0008015 blood circulation 5.03E-05 3.30E-01 1.58E-03 1.48E-02 48 557 "ABAT,MRVI1,MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,PLA2G6,ANK2,SLC2A5,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,GNAS,CACNA1E,NPPA,CACNB2,OLR1,SPX,TGFBR3,GUCY1A1,CDC42,HRH3,PDE2A,PDE4B,CHGA,CHRM1,NOS1AP,PTAFR,PTPRO,KCND3,KCNJ4,KCNJ11,KCNK1,KCNMA1,NAV2,ABCC9,CACNG7,FGFBP3,EPB41" GO: Biological Process GO:0048675 axon extension 5.25E-05 3.44E-01 1.65E-03 1.54E-02 18 132 "MAPT,DRAXIN,SEMA6A,SEMA6C,SHTN1,MT3,SLIT1,CLASP2,SEMA4A,TNR,DCLK1,NLGN3,SEMA5B,PPP3CB,DNM2,DSCAM,RTN4,L1CAM" GO: Biological Process GO:0006936 muscle contraction 5.70E-05 3.74E-01 1.78E-03 1.67E-02 34 348 "ABAT,RCSD1,ACTN2,MRVI1,KCNIP2,RYR1,ADORA1,AGT,SCN4B,PLA2G6,ANK2,SORBS1,SLC8A3,ASPH,ATP1A2,ATP1A3,SCN3B,MYBPC1,MYH7,NPPA,CACNB2,GUCY1A1,TPM3,TPM4,PDE4B,CHGA,CHRM1,CHRNB2,NOS1AP,PTAFR,KCNA1,KCNMA1,DTNA,SSPN" GO: Biological Process GO:0003013 circulatory system process 5.74E-05 3.76E-01 1.78E-03 1.67E-02 48 560 "ABAT,MRVI1,MDM4,KCNIP2,RYR1,ADORA1,AGT,SCN4B,PLA2G6,ANK2,SLC2A5,SLC8A2,SLC8A3,ASPH,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,MYH7,FXYD6,GNAS,CACNA1E,NPPA,CACNB2,OLR1,SPX,TGFBR3,GUCY1A1,CDC42,HRH3,PDE2A,PDE4B,CHGA,CHRM1,NOS1AP,PTAFR,PTPRO,KCND3,KCNJ4,KCNJ11,KCNK1,KCNMA1,NAV2,ABCC9,CACNG7,FGFBP3,EPB41" GO: Biological Process GO:0044065 regulation of respiratory system process 5.98E-05 3.92E-01 1.85E-03 1.73E-02 6 16 "ADORA1,NLGN1,ATP1A2,GLS,NLGN3,FTO" GO: Biological Process GO:0002028 regulation of sodium ion transport 6.47E-05 4.25E-01 1.99E-03 1.87E-02 14 88 "AGT,SCN4B,FGF14,ANK3,ATP1A2,SCN3B,AHCYL1,GNAS,P2RX7,SERPINE2,CNTN1,NKAIN4,NKAIN1,DNM2" GO: Cellular Component GO:0097458 neuron part 3.07E-64 2.10E-61 2.10E-61 1.49E-60 236 1545 "DPF1,MAG,TTYH1,EPS8,ABAT,ZFYVE27,ASIC1,MAPT,ACHE,CDHR1,MBP,SYT9,SYNDIG1,ACTN2,ADGRV1,ATAT1,ARID1A,WLS,NDRG2,ADCY2,ADCYAP1R1,ADD3,FABP7,ERMN,ADORA1,TUBB4A,NLGN4X,SCN3A,LRRC7,SEMA6A,ACTL6B,AMPH,SGIP1,ANK1,ANK2,ANK3,CNIH2,PPFIA1,ITSN1,APBA2,APBB1,APC,BCAN,NLGN1,SHTN1,CLSTN1,SLC1A2,RPH3A,MADD,SLC6A9,SLC8A2,SLC8A3,MT3,SHANK2,CADPS,ASCL1,LGI3,ARFGAP1,BRINP2,SORCS3,SMARCE1,IGSF9B,SNAP25,SNCB,ATP1A2,ATP1A3,ATP2B2,PALLD,GABBR1,GAD2,NMNAT2,JPH4,KIF1B,CPLX2,DNER,RAP1GAP2,NFASC,NCAM1,CLASP2,GFRA1,NCDN,KIRREL3,SEPT3,ARHGEF7,ABCC8,VAMP1,SYT4,GNAS,ROBO3,GNG3,CNTN2,ADGRL3,CACNA1A,GPM6A,CACNA1E,NRGN,HAP1,AZIN2,PTBP2,CAMK2A,CAMK2G,SYT6,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,ATP13A2,PTPN5,P2RX7,NEURL1,TNFRSF1B,CDC42,PCDH8,PCDH9,CDH8,DCLK1,PTGDR2,HRH3,SEZ6L,TPM3,PCSK2,PDE1A,PDE1C,PDE2A,PDE4B,PDYN,ZMYND8,NTSR2,ACOT7,HMGB1,SCRG1,TMPRSS5,CHRM1,PLEKHB1,CHRM4,HNRNPK,HPCA,HEPACAM,NLGN3,DLGAP3,SERPINE2,CADM1,NRXN1,NRXN2,NEGR1,CPT1C,FLRT1,SLC25A27,PACSIN1,FAT3,ATCAY,CRMP1,SNCAIP,TENM4,NKAIN4,FEZ1,RIMS4,DOCK7,SDC3,PRKCG,PRKCZ,CTNND1,CTNND2,NRSN1,MAPK8,MAPK10,BRINP3,RIMS3,DPYSL5,ANKS1B,PTCH1,DNAJC6,CADM2,CNIH3,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,PARD6A,PTPRO,KCND3,PTPRZ1,KCNH1,SV2A,NTM,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,PCDH15,KCNMA1,KCNN3,KCNQ2,DLG2,DLG3,DNM2,SLC17A6,DPP6,RAP1GAP,ABI1,GOPC,DSCAM,RASGRF1,DTNA,RTN4,L1CAM,CRTAC1,CAMK1G,RET,USH1C,RGS7,RGS10,ATL1,TTLL7,EEF1A2,SYT15,ABI2,SLC4A10,ELAVL4,ROM1,TMEM100,EPB41L1,RASGRP2,SEZ6" GO: Cellular Component GO:0043005 neuron projection 8.10E-53 5.53E-50 2.77E-50 1.97E-49 189 1194 "MAG,TTYH1,EPS8,ABAT,ZFYVE27,ASIC1,MAPT,ACHE,MBP,SYNDIG1,ACTN2,ATAT1,WLS,NDRG2,ADCY2,ADCYAP1R1,ERMN,ADORA1,TUBB4A,NLGN4X,SCN3A,LRRC7,SEMA6A,AMPH,SGIP1,ANK1,ANK2,ANK3,CNIH2,ITSN1,APBB1,APC,BCAN,NLGN1,SHTN1,SLC1A2,RPH3A,SLC8A2,SLC8A3,MT3,SHANK2,LGI3,BRINP2,IGSF9B,SNAP25,SNCB,ATP1A2,ATP1A3,ATP2B2,PALLD,GABBR1,GAD2,JPH4,KIF1B,CPLX2,DNER,RAP1GAP2,NFASC,NCAM1,CLASP2,GFRA1,NCDN,KIRREL3,SEPT3,ARHGEF7,VAMP1,SYT4,GNAS,ROBO3,GNG3,CNTN2,ADGRL3,CACNA1A,GPM6A,NRGN,HAP1,AZIN2,PTBP2,CAMK2A,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,ATP13A2,PTPN5,NEURL1,TNFRSF1B,CDC42,PCDH8,PCDH9,CDH8,PTGDR2,HRH3,TPM3,PCSK2,PDE2A,PDE4B,PDYN,ZMYND8,NTSR2,ACOT7,HMGB1,SCRG1,CHRM1,CHRM4,HNRNPK,HPCA,HEPACAM,NLGN3,DLGAP3,CADM1,NRXN1,NEGR1,CPT1C,FLRT1,PACSIN1,FAT3,ATCAY,CRMP1,TENM4,FEZ1,DOCK7,SDC3,PRKCG,PRKCZ,CTNND1,CTNND2,NRSN1,MAPK8,MAPK10,BRINP3,DPYSL5,ANKS1B,PTCH1,CADM2,CNIH3,LRP8,RGMA,MAGI2,STMN4,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,PARD6A,PTPRO,KCND3,PTPRZ1,KCNH1,SV2A,NTM,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG2,DLG3,DNM2,SLC17A6,RAP1GAP,ABI1,GOPC,DSCAM,RASGRF1,DTNA,RTN4,L1CAM,CRTAC1,CAMK1G,RET,RGS7,RGS10,ATL1,TTLL7,ABI2,SLC4A10,ELAVL4,RASGRP2,SEZ6" GO: Cellular Component GO:0045202 synapse 3.63E-48 2.48E-45 8.27E-46 5.87E-45 153 870 "EPS8,ASIC1,MAPT,ACHE,SYT9,SYNDIG1,ACTN2,ADGRV1,DSCAML1,ADD3,ADORA1,NLGN4X,LRRTM4,LRRC7,AMPH,SGIP1,ANK1,ANK2,ANK3,CNIH2,PPFIA1,ITSN1,PKP4,APBA2,APBB1,APC,BCAN,NLGN1,LRRC4C,BCAS1,CLSTN1,SLC1A2,RPH3A,MADD,SLC6A9,SLC8A2,SLC8A3,MT3,SHANK2,CADPS,LGI3,ARFGAP1,SORCS3,IGSF9B,SNAP25,SNCB,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,GAD2,NMNAT2,CPLX2,SPART,SEPT3,ABCC8,VAMP1,SYT4,GNG3,CNTN2,CACNA1A,GPM6A,VWC2,NRGN,HAP1,CAMK2A,CAMK2G,SYT6,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,P2RX7,NEURL1,PCDH8,CDH8,DCLK1,HRH3,LGI1,PDE2A,PDE4B,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,HPCA,NLGN3,DLGAP3,SERPINE2,CADM1,NRXN1,NRXN2,CPT1C,CABP1,PACSIN1,ATCAY,SNCAIP,RIMS4,PRKCG,CTNND1,CTNND2,MAPK10,RIMS3,ANKS1B,SYNC,LRRTM3,PTCH1,DNAJC6,CADM2,CNIH3,LRP8,MAGI2,BLOC1S6,KCNA1,KCNA2,OLFM3,PTPRO,PTPRZ1,KCNH1,SV2A,NTM,KCNJ4,KCNJ10,KCNK1,PCDH15,KCNMA1,KCNN3,DLG2,DLG3,DNM2,SLC17A6,ABI1,GOPC,DSCAM,DTNA,RTN4,L1CAM,USH1C,RGS10,SYT15,SSPN,EPB41L1,RASGRP2,SEZ6" GO: Cellular Component GO:0036477 somatodendritic compartment 6.89E-45 4.70E-42 1.18E-42 8.35E-42 148 867 "ZFYVE27,ASIC1,MAPT,ACHE,MBP,SYNDIG1,ACTN2,WLS,ADCY2,FABP7,ERMN,ADORA1,TUBB4A,NLGN4X,SCN3A,LRRC7,ANK3,CNIH2,APBB1,APC,BCAN,NLGN1,SHTN1,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,ASCL1,BRINP2,IGSF9B,SNAP25,SNCB,ATP1A2,ATP1A3,ATP2B2,PALLD,GABBR1,JPH4,CPLX2,DNER,NCAM1,GFRA1,NCDN,KIRREL3,ARHGEF7,GNAS,GNG3,CNTN2,CACNA1A,GPM6A,CACNA1E,NRGN,HAP1,AZIN2,PTBP2,CAMK2A,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,ATP13A2,PTPN5,P2RX7,NEURL1,TNFRSF1B,CDC42,PCDH8,SEZ6L,PCSK2,PDE1A,PDE1C,PDE2A,PDE4B,PDYN,ZMYND8,NTSR2,TMPRSS5,CHRM1,CHRM4,HNRNPK,HPCA,NLGN3,DLGAP3,SERPINE2,CADM1,NRXN1,NEGR1,CPT1C,FLRT1,SLC25A27,FAT3,ATCAY,CRMP1,SNCAIP,FEZ1,PRKCG,PRKCZ,CTNND1,CTNND2,NRSN1,MAPK8,MAPK10,BRINP3,DPYSL5,ANKS1B,PTCH1,CADM2,CNIH3,LRP8,MAGI2,KCNA1,KCNA2,KCNC1,PARD6A,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,DLG2,DLG3,DPP6,RAP1GAP,GOPC,RASGRF1,RTN4,L1CAM,RET,RGS7,RGS10,TTLL7,EEF1A2,ABI2,SLC4A10,ELAVL4,TMEM100,SEZ6" GO: Cellular Component GO:0044456 synapse part 1.07E-40 7.28E-38 1.46E-38 1.03E-37 127 708 "EPS8,ASIC1,MAPT,ACHE,SYT9,SYNDIG1,ACTN2,ADD3,ADORA1,NLGN4X,LRRTM4,LRRC7,AMPH,SGIP1,ANK1,ANK2,ANK3,CNIH2,PPFIA1,ITSN1,PKP4,APBA2,APBB1,NLGN1,LRRC4C,BCAS1,CLSTN1,SLC1A2,RPH3A,MADD,SLC6A9,SLC8A2,SLC8A3,MT3,SHANK2,CADPS,LGI3,ARFGAP1,SORCS3,SNAP25,SNCB,ATP1A2,ATP1A3,FYN,GABBR1,GAD2,CPLX2,SEPT3,ABCC8,VAMP1,SYT4,GNG3,CACNA1A,GPM6A,NRGN,HAP1,CAMK2A,CAMK2G,SYT6,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,P2RX7,NEURL1,PCDH8,CDH8,DCLK1,HRH3,PDE2A,PDE4B,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,HPCA,NLGN3,DLGAP3,CADM1,NRXN1,NRXN2,CABP1,PACSIN1,SNCAIP,RIMS4,PRKCG,CTNND1,CTNND2,MAPK10,RIMS3,ANKS1B,LRRTM3,PTCH1,DNAJC6,CNIH3,LRP8,MAGI2,BLOC1S6,KCNA1,KCNA2,PTPRO,PTPRZ1,KCNH1,SV2A,KCNJ4,KCNJ10,KCNMA1,DLG2,DLG3,DNM2,SLC17A6,ABI1,GOPC,RTN4,L1CAM,RGS10,SYT15,SSPN,EPB41L1,SEZ6" GO: Cellular Component GO:0030425 dendrite 5.67E-34 3.87E-31 6.46E-32 4.59E-31 106 590 "ZFYVE27,ASIC1,MAPT,ACHE,SYNDIG1,ACTN2,WLS,ADCY2,ADORA1,NLGN4X,LRRC7,ANK3,CNIH2,APBB1,APC,BCAN,NLGN1,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,BRINP2,IGSF9B,ATP1A2,ATP1A3,ATP2B2,GABBR1,JPH4,CPLX2,DNER,NCDN,KIRREL3,GNAS,GNG3,CACNA1A,GPM6A,NRGN,HAP1,AZIN2,CAMK2A,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PTPN5,NEURL1,PCDH8,PCSK2,PDE2A,PDE4B,PDYN,ZMYND8,NTSR2,CHRM1,HNRNPK,HPCA,NLGN3,DLGAP3,CADM1,NEGR1,CPT1C,FAT3,ATCAY,CRMP1,FEZ1,PRKCG,CTNND1,CTNND2,MAPK8,BRINP3,DPYSL5,ANKS1B,PTCH1,CNIH3,LRP8,MAGI2,KCNA1,KCNA2,KCNC1,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNK1,KCNMA1,DLG2,DLG3,RAP1GAP,GOPC,RASGRF1,L1CAM,RET,RGS7,RGS10,TTLL7,ABI2,SLC4A10,ELAVL4,SEZ6" GO: Cellular Component GO:0030424 axon 1.94E-33 1.32E-30 1.89E-31 1.34E-30 103 567 "MAG,TTYH1,ZFYVE27,MAPT,ACHE,MBP,ATAT1,ERMN,ADORA1,TUBB4A,SCN3A,LRRC7,SEMA6A,AMPH,SGIP1,ANK1,ANK3,ITSN1,APBB1,APC,SHTN1,SLC1A2,MT3,SNAP25,SNCB,ATP1A3,PALLD,GABBR1,GAD2,KIF1B,CPLX2,NFASC,NCAM1,CLASP2,GFRA1,NCDN,KIRREL3,VAMP1,ROBO3,CNTN2,ADGRL3,GPM6A,NRGN,HAP1,AZIN2,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PTPN5,TNFRSF1B,CDH8,PDE2A,PDYN,CHRM1,CHRM4,HNRNPK,HPCA,HEPACAM,CADM1,NRXN1,CPT1C,PACSIN1,ATCAY,FEZ1,DOCK7,SDC3,PRKCZ,MAPK8,PTCH1,CADM2,LRP8,STMN4,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,PARD6A,PTPRO,PTPRZ1,KCNH1,SV2A,NTM,KCNJ11,KCNK2,KCNMA1,KCNQ2,DLG2,SLC17A6,RAP1GAP,DSCAM,DTNA,L1CAM,RET,RGS10,ATL1" GO: Cellular Component GO:0044297 cell body 2.57E-32 1.75E-29 2.19E-30 1.56E-29 113 691 "MAPT,ACHE,MBP,SYNDIG1,FABP7,ERMN,ADORA1,TUBB4A,SCN3A,APBB1,APC,SHTN1,SLC8A2,SLC8A3,SHANK2,ASCL1,BRINP2,IGSF9B,SNAP25,SNCB,ATP2B2,PALLD,GABBR1,USP33,CPLX2,DNER,NCAM1,GFAP,GFRA1,NCDN,ARHGEF7,GNAS,GNG3,CNTN2,CACNA1A,GPM6A,CACNA1E,NRGN,AZIN2,PTBP2,CAMK2A,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,ATP13A2,PTPN5,P2RX7,NEURL1,TNFRSF1B,CDC42,SEZ6L,PCSK2,PDE1A,PDE1C,PDYN,NTSR2,ACOT7,TMPRSS5,CHRM4,HPCA,NLGN3,DLGAP3,SERPINE2,NRXN1,NEGR1,FLRT1,SLC25A27,CRMP1,SNCAIP,PRKCZ,CTNND2,NRSN1,MAPK8,MAPK10,BRINP3,DPYSL5,CADM2,LRP8,KCNA1,KCNA2,KCNC1,PARD6A,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,DLG2,DLG3,DPP6,RAP1GAP,RASGRF1,RTN4,L1CAM,RET,RGS10,TTLL7,EEF1A2,RLBP1,SLC4A10,ELAVL4,RPE65,TMEM100,SEZ6" GO: Cellular Component GO:0043025 neuronal cell body 1.31E-31 8.96E-29 9.95E-30 7.07E-29 105 616 "ACHE,MBP,FABP7,ERMN,ADORA1,TUBB4A,SCN3A,APBB1,APC,SHTN1,SLC8A2,SLC8A3,SHANK2,ASCL1,BRINP2,IGSF9B,SNAP25,SNCB,ATP2B2,PALLD,GABBR1,CPLX2,DNER,NCAM1,GFRA1,NCDN,ARHGEF7,GNAS,CNTN2,CACNA1A,GPM6A,CACNA1E,NRGN,AZIN2,PTBP2,CAMK2A,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,ATP13A2,PTPN5,P2RX7,NEURL1,TNFRSF1B,CDC42,SEZ6L,PCSK2,PDE1A,PDE1C,PDYN,NTSR2,TMPRSS5,CHRM4,HPCA,NLGN3,DLGAP3,SERPINE2,NRXN1,NEGR1,FLRT1,SLC25A27,CRMP1,SNCAIP,PRKCZ,CTNND2,NRSN1,MAPK8,MAPK10,BRINP3,DPYSL5,CADM2,LRP8,KCNA1,KCNA2,KCNC1,PARD6A,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,DLG2,DLG3,DPP6,RAP1GAP,RASGRF1,RTN4,L1CAM,RET,RGS10,TTLL7,EEF1A2,SLC4A10,ELAVL4,TMEM100,SEZ6" GO: Cellular Component GO:0044463 cell projection part 7.85E-31 5.36E-28 5.36E-29 3.81E-28 148 1139 "MAG,TTYH1,EPS8,ZFYVE27,ASIC1,MAPT,CDHR1,APC2,MBP,SYNDIG1,ACTN2,ADGRV1,WLS,NDRG2,ADD3,ERMN,ADORA1,TUBB4A,LRRC7,FGR,AMPH,SGIP1,ANK1,ANK3,CNIH2,ITSN1,APBB1,APC,NLGN1,SHTN1,CLSTN1,AQP4,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,SLCO1A2,DNAH17,ARFGAP1,SORCS3,SNAP25,SNCB,ATP1A2,ATP1A3,PALLD,GABBR1,ENKUR,JPH4,KIF1B,CPLX2,NFASC,NCAM1,CLASP2,KIRREL3,ARHGEF7,VAMP1,GNG3,CNTN2,WWC1,GPM6A,NRGN,HAP1,PTBP2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PTPN5,NEURL1,TNFRSF1B,PCDH9,CDH8,DCLK1,TPM3,PDE4B,PDYN,ZMYND8,NTSR2,SCRG1,CHRM1,CHRM4,HNRNPK,HPCA,DLGAP3,CADM1,NRXN1,FLRT1,SPATA6,PACSIN1,OSBPL3,PRKACB,DOCK7,PRKCG,PRKCZ,ARHGEF4,CTNND1,NRSN1,MAPK8,MAPK10,ANKS1B,PTCH1,DNAJC6,ITGAV,CNIH3,STMN4,BLOC1S6,KCNA1,KCNA2,KCNA6,KCNC1,PARD6A,PTPRO,PTPRZ1,KCNH1,SV2A,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,KIF2A,DNAH9,DNM2,SLC17A6,ATG16L1,ABI1,DSCAM,RASGRF1,RTN4,L1CAM,CRTAC1,RGS7,RGS10,ELAVL4,ROM1,PLEKHO1,EPB41L1,RASGRP2,SEZ6" GO: Cellular Component GO:0098794 postsynapse 5.52E-29 3.77E-26 3.43E-27 2.43E-26 85 449 "EPS8,ASIC1,MAPT,ACHE,SYNDIG1,ACTN2,ADD3,ADORA1,NLGN4X,LRRTM4,LRRC7,ANK1,ANK2,ANK3,CNIH2,PKP4,APBB1,NLGN1,LRRC4C,BCAS1,CLSTN1,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,ARFGAP1,SORCS3,ATP1A2,ATP1A3,FYN,GABBR1,GNG3,GPM6A,NRGN,CAMK2A,CAMK2G,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,NEURL1,PCDH8,DCLK1,PDE4B,ZMYND8,CHRM1,CHRM4,CHRNB2,HNRNPK,HPCA,NLGN3,DLGAP3,CABP1,PRKCG,CTNND1,CTNND2,MAPK10,ANKS1B,LRRTM3,PTCH1,DNAJC6,CNIH3,LRP8,MAGI2,PTPRO,PTPRZ1,KCNJ4,KCNMA1,DLG2,DLG3,DNM2,ABI1,GOPC,RTN4,RGS10,SSPN,EPB41L1,SEZ6" GO: Cellular Component GO:0030054 cell junction 7.07E-29 4.83E-26 4.03E-27 2.86E-26 149 1200 "EPS8,RPL38,ACHE,SYT9,SYNDIG1,ACTN2,ATAT1,LDLRAD3,PLEKHG5,DSCAML1,ADCYAP1R1,ADD3,FABP7,NLGN4X,SCN4B,LRRTM4,LRRC7,FHL1,AMPH,CDC42BPA,ANK2,ANK3,CNIH2,PPFIA1,ITSN1,PKP4,APC,MAGI3,SORBS1,NLGN1,LRRC4C,CLSTN1,AQP4,RPH3A,SLC8A3,SHANK2,CADPS,LGI3,SNAP25,ATP1A2,ATP2B2,PALLD,GABBR1,USP33,CADM3,GAD2,ADAM15,STARD10,NFASC,NCAM1,CLASP2,ERBIN,GJB1,RND1,SEPT3,AJAP1,NFIA,MLC1,ARHGEF7,VAMP1,SYT4,KAZN,ADGRL3,VWC2,HAP1,CAMK2A,DDR2,SYT6,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,P2RX7,TJP1,NEURL1,CD81,CDC42,TNS1,PCDH8,PCDH9,LGI1,TPM4,MAGI1,ZNF384,CHRM1,CHRM4,CHRNB2,HNRNPK,JAM2,ARHGAP22,HEPACAM,NLGN3,DLGAP3,CADM1,NRXN1,CPT1C,OPALIN,TJP2,FLRT1,CABP1,PACSIN1,FAAP20,ATCAY,RIMS4,DOCK7,PRKCG,PKN2,PRKCZ,CTNND1,CTNND2,RIMS3,ANKS1B,LRRTM3,ITGAV,CADM2,CNIH3,MAGI2,KCNA1,KCNA2,OLFM3,PARD6A,SV2A,KCNJ4,KCNJ11,KCNK1,DLG2,DLG3,DNM2,SLC17A6,ABI1,ATN1,GOPC,DSCAM,DTNA,L1CAM,NUP214,VANGL2,SSPN,PIANP,ABI2,EPB41,EPB41L2,RASGRP2,SEZ6" GO: Cellular Component GO:0097060 synaptic membrane 6.97E-23 4.76E-20 3.66E-21 2.60E-20 61 298 "ACHE,SYNDIG1,ADORA1,NLGN4X,LRRTM4,LRRC7,ANK1,ANK2,ANK3,CNIH2,APBB1,NLGN1,LRRC4C,CLSTN1,SLC1A2,SHANK2,SNAP25,GABBR1,GAD2,SEPT3,CAMK2A,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,NEURL1,PCDH8,PDE2A,CHRM1,CHRM4,CHRNB2,DLGAP3,NRXN1,NRXN2,CABP1,SNCAIP,RIMS4,PRKCG,ANKS1B,LRRTM3,CNIH3,KCNA1,KCNA2,PTPRZ1,KCNH1,KCNJ4,KCNMA1,DLG2,DLG3,DNM2,ABI1,GOPC,L1CAM,SSPN,EPB41L1" GO: Cellular Component GO:0033267 axon part 9.29E-23 6.34E-20 4.53E-21 3.22E-20 62 309 "MAG,MAPT,MBP,ERMN,ADORA1,TUBB4A,LRRC7,AMPH,SGIP1,ANK1,ANK3,ITSN1,APBB1,APC,SHTN1,SLC1A2,SNAP25,SNCB,PALLD,GABBR1,KIF1B,CPLX2,NFASC,CLASP2,VAMP1,CNTN2,GPM6A,HAP1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,TNFRSF1B,CDH8,PDYN,CHRM1,CHRM4,HNRNPK,CADM1,NRXN1,PACSIN1,PRKCZ,PTCH1,BLOC1S6,KCNA1,KCNA2,KCNA6,KCNC1,PARD6A,KCNH1,SV2A,KCNJ11,KCNK2,KCNMA1,KCNQ2,DLG2,SLC17A6,L1CAM,RGS10" GO: Cellular Component GO:0060076 excitatory synapse 2.33E-21 1.59E-18 1.06E-19 7.54E-19 54 252 "EPS8,MAPT,SYNDIG1,ADD3,ADORA1,NLGN4X,LRRC7,CNIH2,PKP4,NLGN1,BCAS1,CLSTN1,MT3,SHANK2,ARFGAP1,SORCS3,FYN,GNG3,NRGN,CAMK2A,CAMK2G,PSD3,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,NEURL1,DCLK1,PDE4B,CHRM1,CHRM4,HNRNPK,NLGN3,DLGAP3,CABP1,PRKCG,CTNND2,MAPK10,ANKS1B,PTCH1,DNAJC6,LRP8,MAGI2,NTM,DLG2,DLG3,DNM2,SLC17A6,ABI1,GOPC,RTN4,EPB41L1" GO: Cellular Component GO:0098590 plasma membrane region 6.24E-21 4.26E-18 2.66E-19 1.89E-18 121 1041 "TTYH1,EPS8,ACHE,CDHR1,APC2,SYNDIG1,ADGRV1,WLS,ADCYAP1R1,ADORA1,NLGN4X,LRRTM4,LRRC7,FGR,ANK1,ANK2,ANK3,CNIH2,APBB1,APC,SORBS1,NLGN1,LRRC4C,CLSTN1,AQP4,SLC1A2,SLC2A5,SLC8A2,SHANK2,SLC14A1,SLCO1A2,SNAP25,ATP1A2,ATP2B2,MEGF11,GABBR1,TNIK,GAD2,AHCYL1,CLASP2,ERBIN,SEPT3,AJAP1,MLC1,WWC1,DDR1,CAMK2A,DDR2,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,TF,CRB1,TJP1,NEURL1,CD81,PCDH8,PDE2A,CHRM1,CHRM4,CHRNB2,HPCA,SLC22A6,DLGAP3,CADM1,NRXN1,NRXN2,CABP1,BEST1,P2RY12,PACSIN1,SNCAIP,RIMS4,PRKAB2,PRKCG,PRKCZ,ARHGEF4,CTNND1,NOS1AP,ACY3,ANKS1B,LRRTM3,PTCH1,ITGAV,CNIH3,LRP8,KCNA1,KCNA2,KCNC1,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,DLG2,DLG3,DNM2,ABI1,GOPC,RASGRF1,L1CAM,VANGL2,SSPN,PIANP,SLC4A10,ROM1,PLEKHO1,EPB41L1,RASGRP2" GO: Cellular Component GO:0014069 postsynaptic density 9.31E-21 6.36E-18 3.53E-19 2.51E-18 51 232 "EPS8,MAPT,SYNDIG1,ADD3,ADORA1,NLGN4X,LRRC7,CNIH2,PKP4,NLGN1,BCAS1,CLSTN1,MT3,SHANK2,ARFGAP1,SORCS3,FYN,GNG3,NRGN,CAMK2A,CAMK2G,PSD3,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,NEURL1,DCLK1,PDE4B,CHRM1,CHRM4,HNRNPK,DLGAP3,CABP1,PRKCG,CTNND2,MAPK10,ANKS1B,PTCH1,DNAJC6,LRP8,MAGI2,DLG2,DLG3,DNM2,ABI1,GOPC,RTN4,EPB41L1" GO: Cellular Component GO:0099572 postsynaptic specialization 9.31E-21 6.36E-18 3.53E-19 2.51E-18 51 232 "EPS8,MAPT,SYNDIG1,ADD3,ADORA1,NLGN4X,LRRC7,CNIH2,PKP4,NLGN1,BCAS1,CLSTN1,MT3,SHANK2,ARFGAP1,SORCS3,FYN,GNG3,NRGN,CAMK2A,CAMK2G,PSD3,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,NEURL1,DCLK1,PDE4B,CHRM1,CHRM4,HNRNPK,DLGAP3,CABP1,PRKCG,CTNND2,MAPK10,ANKS1B,PTCH1,DNAJC6,LRP8,MAGI2,DLG2,DLG3,DNM2,ABI1,GOPC,RTN4,EPB41L1" GO: Cellular Component GO:0098793 presynapse 1.95E-20 1.33E-17 7.01E-19 4.98E-18 62 341 "ACHE,SYT9,SYNDIG1,ADORA1,AMPH,SGIP1,PPFIA1,ITSN1,APBA2,APBB1,NLGN1,SLC1A2,RPH3A,MADD,SLC6A9,MT3,SHANK2,CADPS,LGI3,SNAP25,SNCB,GABBR1,GAD2,CPLX2,SEPT3,ABCC8,VAMP1,SYT4,CACNA1A,HAP1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,P2RX7,PCDH8,HRH3,PDE2A,PDE4B,CADM1,NRXN1,NRXN2,PACSIN1,SNCAIP,RIMS4,RIMS3,BLOC1S6,KCNA1,KCNA2,KCNH1,SV2A,KCNJ10,KCNMA1,SLC17A6,L1CAM,SYT15" GO: Cellular Component GO:0098589 membrane region 6.43E-20 4.39E-17 2.20E-18 1.56E-17 135 1267 "TTYH1,EPS8,ACHE,CDHR1,APC2,SYNDIG1,ADGRV1,ATAT1,WLS,ADCY2,ADCYAP1R1,ADORA1,NLGN4X,FCGR1A,LRRTM4,LRRC7,FGR,MOG,SGIP1,ANK1,ANK2,ANK3,CNIH2,ITSN1,APBB1,APC,SORBS1,NLGN1,LRRC4C,CLSTN1,AQP4,SLC1A2,SLC2A5,SLC8A2,SHANK2,SLC14A1,SLCO1A2,SNAP25,ATP1A2,FYN,ATP2B2,MEGF11,GABBR1,TNIK,GAD2,AHCYL1,CLASP2,ERBIN,SEPT3,AJAP1,MLC1,GNAS,WWC1,GPM6B,DDR1,CAMK2A,DDR2,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,TF,OLR1,CRB1,TJP1,NEURL1,CD81,TNFRSF1B,TNR,PCDH8,PDE2A,CHRM1,CHRM4,CHRNB2,HPCA,SLC22A6,DLGAP3,CADM1,NRXN1,NRXN2,CNTN1,CABP1,BEST1,P2RY12,PACSIN1,SNCAIP,RIMS4,PRKAB2,PRKCG,PRKCZ,ARHGEF4,CTNND1,NOS1AP,ACY3,ANKS1B,LRRTM3,PTCH1,ITGAV,CNIH3,LRP8,KCNA1,KCNA2,KCNC1,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,DLG2,DLG3,DNM2,ABI1,GOPC,RASGRF1,L1CAM,RET,VANGL2,SSPN,PIANP,SLC4A10,ROM1,PLEKHO1,EPB41L1,RASGRP2" GO: Cellular Component GO:0034702 ion channel complex 2.33E-18 1.59E-15 7.59E-17 5.39E-16 54 291 "TTYH1,EPS8,KCNIP2,SCN3A,SCN4B,LRRTM4,CNIH2,NLGN1,SHANK2,ASPH,SNAP25,SCN3B,ABCC8,CNTN2,CACNA1A,CACNA1E,VWC2,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,SHISA7,PDE4B,BEST3,CHRNB2,DLGAP3,CPT1C,BEST1,PTPA,KCNT2,NOS1AP,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,DPP6,ABCC9,CACNG7" GO: Cellular Component GO:1902495 transmembrane transporter complex 2.45E-17 1.67E-14 7.61E-16 5.40E-15 56 327 "TTYH1,EPS8,KCNIP2,SCN3A,SCN4B,LRRTM4,CNIH2,NLGN1,SHANK2,ASPH,SNAP25,ATP1A2,ATP1A3,SCN3B,ABCC8,CNTN2,CACNA1A,CACNA1E,VWC2,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,SHISA7,PDE4B,BEST3,CHRNB2,DLGAP3,CPT1C,BEST1,PTPA,KCNT2,NOS1AP,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,DPP6,ABCC9,CACNG7" GO: Cellular Component GO:1990351 transporter complex 5.71E-17 3.90E-14 1.70E-15 1.20E-14 56 333 "TTYH1,EPS8,KCNIP2,SCN3A,SCN4B,LRRTM4,CNIH2,NLGN1,SHANK2,ASPH,SNAP25,ATP1A2,ATP1A3,SCN3B,ABCC8,CNTN2,CACNA1A,CACNA1E,VWC2,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,SHISA7,PDE4B,BEST3,CHRNB2,DLGAP3,CPT1C,BEST1,PTPA,KCNT2,NOS1AP,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,DPP6,ABCC9,CACNG7" GO: Cellular Component GO:0045211 postsynaptic membrane 8.68E-17 5.93E-14 2.47E-15 1.76E-14 45 225 "ACHE,SYNDIG1,ADORA1,NLGN4X,LRRTM4,LRRC7,ANK1,ANK2,ANK3,CNIH2,APBB1,NLGN1,LRRC4C,CLSTN1,SHANK2,GABBR1,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,NEURL1,PCDH8,CHRM1,CHRM4,CHRNB2,DLGAP3,CABP1,ANKS1B,LRRTM3,CNIH3,PTPRZ1,KCNJ4,KCNMA1,DLG2,DLG3,DNM2,ABI1,GOPC,SSPN" GO: Cellular Component GO:0005887 integral component of plasma membrane 9.39E-16 6.42E-13 2.49E-14 1.77E-13 150 1651 "EPS8,ASIC1,CDHR1,LGR4,SYNDIG1,KCNIP2,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,NLGN4X,SCN3A,SCN4B,LRRTM4,SEMA6A,ASIC4,SELL,SEMA6C,FOLH1,CNIH2,SORBS1,NLGN1,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC2A5,MSR1,SLC6A9,SLC8A2,SLC8A3,SHANK2,SLC14A1,CSPG5,SLCO1A2,SNAP25,ATP1A2,NRG3,ATP1A3,ATP2B2,GABBR1,SCN3B,CADM3,SLCO1C1,ABCC8,VAMP1,PCDH11X,CNTN2,ADGRL3,VWC2,DDR1,CACNB2,PRLHR,GPR17,GPR19,DDR2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GPR88,GRM3,ATP13A2,OLR1,SHISA7,CCKBR,TGFBR3,MFSD2A,P2RX7,TIE1,KCNK10,CD81,TNFRSF1B,PCDH8,PCDH9,DCLK1,PTGDR2,HRH3,NTSR2,BEST3,ADGRG1,ASIC3,CHRM1,CHRM4,CHRNB2,JAM2,SLC22A6,NLGN3,DLGAP3,CADM1,NRXN1,CPT1C,FADS2,FLRT1,PLXNB3,BEST1,P2RY12,TENM4,KCNT2,CSF3R,CALY,PLPP4,NOS1AP,PLPPR5,SIRPA,PTAFR,PTCH1,ITGAV,PLPPR1,CADM2,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,PTPRD,KCNA6,PLPPR4,KCNC1,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,KLRC2,DPP6,DSCAM,ABCC9,SLC6A15,RET,RGR,SLC39A12,SSPN,CACNG7,EFNA3,SLC4A10,ROM1" GO: Cellular Component GO:0031226 intrinsic component of plasma membrane 9.49E-16 6.48E-13 2.49E-14 1.77E-13 154 1714 "EPS8,ASIC1,CDHR1,LGR4,SYNDIG1,KCNIP2,F3,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,NLGN4X,SCN3A,SCN4B,LRRTM4,SEMA6A,ASIC4,SELL,SEMA6C,RASA3,FOLH1,CNIH2,NTNG1,SORBS1,NLGN1,AQP4,SLC1A2,SLC7A14,SLC1A6,SLC2A5,MSR1,SLC6A9,SLC8A2,SLC8A3,SHANK2,SLC14A1,CSPG5,SLCO1A2,SNAP25,ATP1A2,NRG3,ATP1A3,ATP2B2,GABBR1,SCN3B,CADM3,SLCO1C1,ABCC8,VAMP1,PCDH11X,CNTN2,ADGRL3,VWC2,DDR1,CACNB2,PRLHR,GPR17,GPR19,DDR2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GPR88,GRM3,ATP13A2,OLR1,SHISA7,CCKBR,TGFBR3,MFSD2A,P2RX7,TIE1,KCNK10,CD81,TNFRSF1B,PCDH8,PCDH9,DCLK1,PTGDR2,HRH3,NTSR2,BEST3,ADGRG1,ASIC3,CHRM1,CHRM4,CHRNB2,JAM2,SLC22A6,NLGN3,DLGAP3,CADM1,NRXN1,CPT1C,FADS2,FLRT1,PLXNB3,BEST1,P2RY12,CP,TENM4,KCNT2,CSF3R,CALY,PLPP4,NOS1AP,PLPPR5,SIRPA,PTAFR,PTCH1,ITGAV,PLPPR1,CADM2,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,PTPRD,KCNA6,PLPPR4,KCNC1,PTPRO,KCND3,PTPRZ1,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,KLRC2,DPP6,DSCAM,ABCC9,SLC6A15,RET,RGR,SLC39A12,SSPN,CACNG7,EFNA3,SLC4A10,ROM1" GO: Cellular Component GO:0030426 growth cone 5.13E-15 3.50E-12 1.30E-13 9.21E-13 38 182 "EPS8,ZFYVE27,MAPT,NDRG2,APBB1,APC,SHTN1,SHANK2,SNAP25,SNCB,PALLD,NCAM1,CLASP2,ARHGEF7,GPM6A,HAP1,PTBP2,GRIA2,GRIN1,PCDH9,TPM3,NRXN1,DOCK7,CTNND1,NRSN1,PTCH1,STMN4,PARD6A,PTPRO,PTPRZ1,DLG3,DNM2,ABI1,DSCAM,RASGRF1,L1CAM,CRTAC1,ELAVL4" GO: Cellular Component GO:0030427 site of polarized growth 1.29E-14 8.83E-12 3.16E-13 2.24E-12 38 187 "EPS8,ZFYVE27,MAPT,NDRG2,APBB1,APC,SHTN1,SHANK2,SNAP25,SNCB,PALLD,NCAM1,CLASP2,ARHGEF7,GPM6A,HAP1,PTBP2,GRIA2,GRIN1,PCDH9,TPM3,NRXN1,DOCK7,CTNND1,NRSN1,PTCH1,STMN4,PARD6A,PTPRO,PTPRZ1,DLG3,DNM2,ABI1,DSCAM,RASGRF1,L1CAM,CRTAC1,ELAVL4" GO: Cellular Component GO:0043197 dendritic spine 1.34E-14 9.16E-12 3.16E-13 2.24E-12 34 151 "ASIC1,SYNDIG1,ACTN2,ADORA1,LRRC7,CNIH2,APBB1,NLGN1,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,ATP1A2,ATP1A3,GABBR1,GPM6A,NRGN,GRIA1,GRIA2,GRIN1,GRM3,NEURL1,PDE4B,ZMYND8,HNRNPK,HPCA,DLGAP3,CTNND1,ANKS1B,PTPRO,PTPRZ1,RGS10,SEZ6" GO: Cellular Component GO:0044309 neuron spine 2.03E-14 1.39E-11 4.62E-13 3.28E-12 34 153 "ASIC1,SYNDIG1,ACTN2,ADORA1,LRRC7,CNIH2,APBB1,NLGN1,SLC1A2,SLC8A2,SLC8A3,MT3,SHANK2,ATP1A2,ATP1A3,GABBR1,GPM6A,NRGN,GRIA1,GRIA2,GRIN1,GRM3,NEURL1,PDE4B,ZMYND8,HNRNPK,HPCA,DLGAP3,CTNND1,ANKS1B,PTPRO,PTPRZ1,RGS10,SEZ6" GO: Cellular Component GO:0008328 ionotropic glutamate receptor complex 2.62E-14 1.79E-11 5.76E-13 4.09E-12 20 50 "EPS8,LRRTM4,CNIH2,NLGN1,SHANK2,VWC2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,SHISA7,DLGAP3,CPT1C,CNIH3,OLFM3,DLG2,DLG3,CACNG7" GO: Cellular Component GO:0098797 plasma membrane protein complex 4.43E-14 3.03E-11 9.45E-13 6.72E-12 68 532 "EPS8,APC2,KCNIP2,SCN3A,SCN4B,LRRTM4,SGIP1,CNIH2,APC,SORBS1,NLGN1,SHANK2,SNAP25,ATP1A2,ATP1A3,GABBR1,SCN3B,GJB1,ABCC8,GNAS,GNG3,GNG4,CNTN2,CACNA1A,CACNA1E,VWC2,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,TF,SHISA7,TGFBR3,PDE4B,CHRNB2,DLGAP3,CPT1C,RGS6,KCNT2,CTNND1,NOS1AP,ITGAV,CNIH3,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DLG3,DPP6,DTNA,ABCC9,RGS7,SSPN,CACNG7" GO: Cellular Component GO:0044304 main axon 1.71E-13 1.17E-10 3.54E-12 2.52E-11 23 74 "MAG,MAPT,MBP,ERMN,ADORA1,TUBB4A,LRRC7,ANK1,ANK3,APBB1,SLC1A2,GABBR1,NFASC,CNTN2,TNFRSF1B,CADM1,KCNA1,KCNA2,KCNC1,KCNH1,KCNJ11,KCNQ2,DLG2" GO: Cellular Component GO:0042734 presynaptic membrane 3.24E-13 2.21E-10 6.50E-12 4.62E-11 23 76 "ACHE,ADORA1,APBB1,SLC1A2,SNAP25,GABBR1,GAD2,SEPT3,CAMK2A,GRIA2,GRIK2,GRIK4,GRM3,PCDH8,PDE2A,NRXN1,NRXN2,SNCAIP,KCNA1,KCNA2,KCNH1,KCNMA1,L1CAM" GO: Cellular Component GO:0034703 cation channel complex 3.59E-11 2.45E-08 7.01E-10 4.98E-09 32 176 "KCNIP2,SCN3A,SCN4B,ASPH,SNAP25,SCN3B,ABCC8,CNTN2,CACNA1A,CACNA1E,CACNB2,PDE4B,PTPA,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DPP6,ABCC9,CACNG7" GO: Cellular Component GO:0008076 voltage-gated potassium channel complex 1.80E-10 1.23E-07 3.41E-09 2.42E-08 22 92 "KCNIP2,SNAP25,ABCC8,CNTN2,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DPP6,ABCC9" GO: Cellular Component GO:0034705 potassium channel complex 2.25E-10 1.54E-07 4.16E-09 2.96E-08 22 93 "KCNIP2,SNAP25,ABCC8,CNTN2,KCNT2,NOS1AP,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,DLG2,DPP6,ABCC9" GO: Cellular Component GO:0031252 cell leading edge 2.89E-10 1.97E-07 5.19E-09 3.69E-08 49 389 "EPS8,APC2,WLS,CLIP1,PLEKHG5,ADORA1,FGR,AMPH,CDC42BPA,ANK1,ITSN1,APBB1,APC,GAS7,DGKZ,SHTN1,SLC1A2,CCDC88A,SNAP25,PALLD,GABBR1,CLASP2,ARHGEF7,GNAS,WWC1,GRIA1,GRIN1,CDC42,HPCA,PACSIN1,PKN2,PRKCZ,ARHGEF4,CTNND1,PSD,ITGAV,KCNA2,KCNC1,PARD6A,PTPRO,PTPRZ1,KCNH1,KCNJ11,DNM2,ABI1,ATN1,ABI2,PLEKHO1,RASGRP2" GO: Cellular Component GO:0044306 neuron projection terminus 9.42E-10 6.43E-07 1.65E-08 1.17E-07 32 199 "ADORA1,AMPH,SGIP1,ITSN1,APC,SNAP25,SNCB,CPLX2,VAMP1,HAP1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,CDH8,PDYN,SCRG1,CHRM1,CHRM4,HNRNPK,FLRT1,PACSIN1,KCNA1,KCNA2,KCNA6,SV2A,KCNK2,KCNMA1,L1CAM,RGS10" GO: Cellular Component GO:0031256 leading edge membrane 1.54E-09 1.05E-06 2.62E-08 1.86E-07 27 150 "EPS8,APC2,WLS,ADORA1,FGR,AMPH,ANK1,APC,SLC1A2,GABBR1,CLASP2,WWC1,GRIA1,GRIN1,CDC42,HPCA,PACSIN1,ARHGEF4,ITGAV,KCNA2,KCNC1,PTPRZ1,KCNH1,KCNJ11,DNM2,PLEKHO1,RASGRP2" GO: Cellular Component GO:0032281 AMPA glutamate receptor complex 4.12E-09 2.81E-06 6.85E-08 4.87E-07 12 30 "LRRTM4,CNIH2,VWC2,GRIA1,GRIA2,GRIA4,SHISA7,CPT1C,CNIH3,OLFM3,DLG3,CACNG7" GO: Cellular Component GO:0043679 axon terminus 1.18E-08 8.05E-06 1.92E-07 1.36E-06 29 186 "ADORA1,AMPH,SGIP1,ITSN1,SNAP25,SNCB,CPLX2,VAMP1,HAP1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,CDH8,PDYN,CHRM1,CHRM4,HNRNPK,PACSIN1,KCNA1,KCNA2,KCNA6,SV2A,KCNK2,KCNMA1,L1CAM,RGS10" GO: Cellular Component GO:0043235 receptor complex 2.68E-08 1.83E-05 4.26E-07 3.03E-06 41 339 "EPS8,ADGRV1,ADCYAP1R1,LRRTM4,CNIH2,SORBS1,NLGN1,SHANK2,CAPRIN2,GABBR1,GFRA1,VWC2,DDR1,GRIA1,GRIA2,GRIA4,RFFL,GRIK2,GRIK4,GRIN1,TF,OLR1,SHISA7,TGFBR3,GPR37L1,CHRNB2,DLGAP3,CPT1C,PLXNB3,NOS1AP,ITGAV,CNIH3,LRP8,OLFM3,KCNK1,DLG2,DLG3,KLRC2,RET,CACNG7,GPR61" GO: Cellular Component GO:0044295 axonal growth cone 3.57E-08 2.44E-05 5.55E-07 3.94E-06 11 29 "MAPT,APC,SHTN1,SNAP25,PALLD,CLASP2,GPM6A,NRXN1,PTCH1,PARD6A,L1CAM" GO: Cellular Component GO:0043198 dendritic shaft 7.53E-08 5.14E-05 1.14E-06 8.12E-06 15 60 "ASIC1,SYNDIG1,CNIH2,NLGN1,SLC1A2,GABBR1,JPH4,KIRREL3,GRIA1,GRIA2,ZMYND8,NTSR2,CNIH3,DLG3,SEZ6" GO: Cellular Component GO:0098802 plasma membrane receptor complex 8.54E-08 5.83E-05 1.27E-06 9.01E-06 27 180 "EPS8,LRRTM4,CNIH2,SORBS1,NLGN1,SHANK2,GABBR1,VWC2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,TF,SHISA7,CHRNB2,DLGAP3,CPT1C,NOS1AP,ITGAV,CNIH3,OLFM3,KCNK1,DLG2,DLG3,CACNG7" GO: Cellular Component GO:0005911 cell-cell junction 1.84E-07 1.26E-04 2.66E-06 1.89E-05 45 418 "PLEKHG5,ADCYAP1R1,ADD3,FABP7,SCN4B,CDC42BPA,ANK2,ANK3,PKP4,APC,MAGI3,SORBS1,AQP4,ATP1A2,CADM3,STARD10,NFASC,NCAM1,GJB1,MLC1,KAZN,ADGRL3,P2RX7,TJP1,CDC42,PCDH9,MAGI1,JAM2,HEPACAM,CADM1,OPALIN,TJP2,FLRT1,PRKCG,PKN2,PRKCZ,CTNND1,CADM2,MAGI2,PARD6A,SV2A,KCNJ11,DLG3,VANGL2,ABI2" GO: Cellular Component GO:0043204 perikaryon 1.87E-07 1.28E-04 2.66E-06 1.89E-05 23 142 "SHTN1,SLC8A2,SLC8A3,CACNA1A,CACNA1E,AZIN2,GRIA2,GRIK2,GRIK3,GRIK4,PTPN5,NEURL1,PCSK2,NTSR2,HPCA,CTNND2,MAPK8,MAPK10,KCNA1,KCNA2,KCNK1,TTLL7,TMEM100" GO: Cellular Component GO:0099568 cytoplasmic region 2.09E-07 1.43E-04 2.91E-06 2.07E-05 38 325 "EPS8,ACTN2,WLS,RYR1,ADD3,ERMN,FGF1,PDZD4,ANK1,APC,ASPH,KIF1B,CLASP2,STOX1,PHLDB1,ARHGEF7,HAP1,CAMK2A,NUMA1,GRIA2,GRIK2,GRIK3,USP2,TPM3,TPM4,HNRNPK,HPCA,ANLN,CABP1,FMN2,PRKCZ,MAPK8,SPIRE1,BLOC1S6,PARD6A,WIPF2,EPB41,EPB41L2" GO: Cellular Component GO:0048471 perinuclear region of cytoplasm 7.89E-07 5.39E-04 1.08E-05 7.65E-05 64 724 "MAP6,ACHE,APC2,ADGRV1,MRVI1,NDRG2,PLEKHG5,HHATL,MOBP,PKP4,APBB1,SHTN1,SLC8A3,MT3,SNAP25,USP33,TNIK,GAD2,RAP1GAP2,NELL1,MLC1,SYT4,GNAS,MMD2,WWC1,NPPA,HAP1,AZIN2,SYT6,BRSK2,TF,USP2,AIFM1,NEURL1,MAEL,TNFRSF1B,TPD52,PDE2A,PDE4B,CHGA,FLRT1,CABP1,PACSIN1,OSBPL3,PRKACB,FMN2,PRKCG,PKN2,PRKCZ,NOS1AP,SPIRE1,SYNC,PTCH1,MAGI2,KCND3,KCNH1,NTM,KCNMA1,CALN1,DNM2,ATN1,SLC39A12,TMEM100,SEZ6" GO: Cellular Component GO:0008021 synaptic vesicle 1.04E-06 7.11E-04 1.37E-05 9.75E-05 23 156 "SYT9,AMPH,APBA2,RPH3A,MADD,MT3,LGI3,SNAP25,GABBR1,GAD2,ABCC8,VAMP1,SYT4,HAP1,SYT6,GRIA1,GRIA2,GRIN1,PDE4B,CADM1,SNCAIP,SV2A,SLC17A6" GO: Cellular Component GO:0030133 transport vesicle 1.04E-06 7.13E-04 1.37E-05 9.75E-05 40 374 "RABEPK,SYT9,AMPH,CNIH2,APBA2,RPH3A,MADD,MT3,SCG3,LGI3,SNAP25,GABBR1,GAD2,ABCC8,VAMP1,SYT4,GNAS,NRGN,HAP1,AZIN2,SYT6,GRIA1,GRIA2,GRIN1,ATP13A2,SPX,PCSK2,PDE4B,CHGA,CADM1,SNCAIP,NRSN1,SYTL2,CNIH3,BLOC1S6,SV2A,SLC17A6,GOPC,VANGL2,SSPN" GO: Cellular Component GO:0070382 exocytic vesicle 1.68E-06 1.15E-03 2.16E-05 1.54E-04 24 172 "SYT9,AMPH,APBA2,RPH3A,MADD,MT3,LGI3,SNAP25,GABBR1,GAD2,ABCC8,VAMP1,SYT4,HAP1,SYT6,GRIA1,GRIA2,GRIN1,PDE4B,CADM1,SNCAIP,SYTL2,SV2A,SLC17A6" GO: Cellular Component GO:0098796 membrane protein complex 2.63E-06 1.79E-03 3.32E-05 2.36E-04 83 1059 "TTYH1,EPS8,APC2,KCNIP2,TOMM40L,SCN3A,SCN4B,LRRTM4,SGIP1,CNIH2,APC,SORBS1,NLGN1,SHANK2,ASPH,SNAP25,ATP1A2,ATP1A3,GABBR1,SCN3B,EMC1,CPLX2,NDUFA5,GJB1,ABCC8,VAMP1,OS9,GNAS,GNG3,GNG4,CNTN2,CACNA1A,CACNA1E,VWC2,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,TF,SHISA7,TGFBR3,PDE4B,BEST3,CHRNB2,DLGAP3,PIK3CD,CPT1C,BEST1,PTPA,RGS6,KCNT2,CTNND1,NOS1AP,TOMM20,ITGAV,CNIH3,BLOC1S6,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,SNX27,KCNQ2,DLG2,DLG3,DPP6,DTNA,ABCC9,RGS7,SSPN,CACNG7" GO: Cellular Component GO:0043209 myelin sheath 2.95E-06 2.01E-03 3.66E-05 2.60E-04 26 202 "MAG,MBP,ERMN,TUBB4A,MOBP,MOG,TAGLN3,SNAP25,ATP1A2,ATP1A3,NFASC,NCAM1,GFAP,CNTN2,OMG,INA,CDC42,HRH3,CNTN1,PMP2,PACSIN1,CNRIP1,PRKCZ,KCNJ11,RTN4,EEF1A2" GO: Cellular Component GO:0098858 actin-based cell projection 3.55E-06 2.42E-03 4.32E-05 3.07E-04 26 204 "TTYH1,EPS8,ACTN2,ADGRV1,ERMN,LRRC7,APBB1,NLGN1,SHTN1,SNAP25,PALLD,STARD10,NFASC,GPM6A,CRB1,CDC42,OSBPL3,FMN2,ITGAV,PTPRZ1,KCNJ10,PCDH15,KCNN3,ABI1,USH1C,ABI2" GO: Cellular Component GO:0043195 terminal bouton 4.42E-06 3.02E-03 5.30E-05 3.76E-04 18 112 "ADORA1,AMPH,SGIP1,ITSN1,SNAP25,SNCB,CPLX2,VAMP1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,PACSIN1,SV2A,KCNMA1,L1CAM" GO: Cellular Component GO:0030175 filopodium 4.89E-06 3.34E-03 5.75E-05 4.09E-04 17 102 "TTYH1,ACTN2,ERMN,LRRC7,APBB1,NLGN1,SHTN1,SNAP25,PALLD,GPM6A,CDC42,OSBPL3,ITGAV,PTPRZ1,KCNN3,ABI1,ABI2" GO: Cellular Component GO:0042383 sarcolemma 8.62E-06 5.89E-03 9.98E-05 7.09E-04 21 152 "RYR1,ANK1,ANK2,ANK3,AQP4,SLC2A5,SLC8A3,ATP1A2,ATP1A3,ABCC8,GNAS,CACNB2,CHRM4,PPP3CB,NOS1AP,SYNC,KCND3,KCNJ11,DTNA,ABCC9,SSPN" GO: Cellular Component GO:0097386 glial cell projection 9.78E-06 6.68E-03 1.11E-04 7.91E-04 7 18 "MT3,NFASC,GFAP,GRM3,ADGRG1,KCNJ10,KCNK2" GO: Cellular Component GO:0032589 neuron projection membrane 1.27E-05 8.69E-03 1.43E-04 1.01E-03 11 49 "WLS,ADORA1,ANK1,SLC1A2,GABBR1,GRIA1,GRIN1,HPCA,KCNC1,KCNH1,KCNJ11" GO: Cellular Component GO:0097449 astrocyte projection 1.34E-05 9.18E-03 1.48E-04 1.05E-03 6 13 "MT3,GFAP,GRM3,ADGRG1,KCNJ10,KCNK2" GO: Cellular Component GO:0030673 axolemma 1.49E-05 1.01E-02 1.61E-04 1.14E-03 7 19 "ADORA1,ANK1,SLC1A2,GABBR1,KCNC1,KCNH1,KCNJ11" GO: Cellular Component GO:0031253 cell projection membrane 1.68E-05 1.15E-02 1.79E-04 1.27E-03 34 332 "TTYH1,EPS8,CDHR1,APC2,ADGRV1,WLS,ADORA1,FGR,ANK1,APC,AQP4,SLC1A2,SHANK2,SLCO1A2,GABBR1,CLASP2,WWC1,GRIA1,GRIN1,HPCA,PACSIN1,ARHGEF4,PTCH1,ITGAV,KCNA2,KCNC1,PTPRZ1,KCNH1,KCNJ11,KCNK1,DNM2,ROM1,PLEKHO1,RASGRP2" GO: Cellular Component GO:0030659 cytoplasmic vesicle membrane 1.99E-05 1.36E-02 2.09E-04 1.48E-03 46 513 "SYT9,WLS,CLIP1,FCGR1A,FCGR1B,DISP3,AMPH,SGIP1,CNIH2,ANXA7,SH3GL2,RPH3A,MSR1,NSG2,CADPS,SCG3,CSPG5,GAD2,KIF1B,ABCC8,VAMP1,SYT4,NRGN,CAMK2A,CAMK2G,SYT6,GRIA1,GRIA2,GRIA4,TF,CHGA,CAMKV,FLRT1,PACSIN1,FMN2,CALY,RAB39A,ECE2,SPIRE1,PTCH1,CNIH3,SV2A,KCNJ4,DNM2,SLC17A6,GOPC" GO: Cellular Component GO:0012506 vesicle membrane 2.72E-05 1.86E-02 2.82E-04 2.00E-03 47 535 "SYT9,WLS,CLIP1,FCGR1A,FCGR1B,DISP3,AMPH,SGIP1,CNIH2,ANXA7,SH3GL2,RPH3A,MSR1,NSG2,CADPS,SCG3,CSPG5,GAD2,KIF1B,ABCC8,VAMP1,SYT4,NRGN,CAMK2A,CAMK2G,SYT6,GRIA1,GRIA2,GRIA4,ATP13A2,TF,CHGA,CAMKV,FLRT1,PACSIN1,FMN2,CALY,RAB39A,ECE2,SPIRE1,PTCH1,CNIH3,SV2A,KCNJ4,DNM2,SLC17A6,GOPC" GO: Cellular Component GO:0032839 dendrite cytoplasm 3.16E-05 2.16E-02 3.22E-04 2.29E-03 7 21 "WLS,CAMK2A,GRIA2,GRIK2,GRIK3,HPCA,MAPK8" GO: Cellular Component GO:0019898 extrinsic component of membrane 4.91E-05 3.36E-02 4.94E-04 3.51E-03 29 278 "APC2,RYR1,SNX30,SNX32,FGR,APC,RPH3A,FYN,SOX10,GFRA1,GNAS,GNG3,GNG4,SYT6,NUCB1,TF,OLR1,SERPINE2,PIK3CD,NMT2,RGS6,SYTL2,BLOC1S6,DTNA,RGS7,SYT15,EPB41,EPB41L1,EPB41L2" GO: Cellular Component GO:0005938 cell cortex 5.62E-05 3.84E-02 5.56E-04 3.95E-03 28 266 "EPS8,ACTN2,RYR1,ADD3,ERMN,FGF1,PDZD4,ANK1,APC,ASPH,CLASP2,STOX1,PHLDB1,ARHGEF7,NUMA1,USP2,TPM3,TPM4,HNRNPK,ANLN,CABP1,FMN2,PRKCZ,SPIRE1,PARD6A,WIPF2,EPB41,EPB41L2" GO: Cellular Component GO:0031410 cytoplasmic vesicle 7.60E-05 5.19E-02 7.41E-04 5.27E-03 94 1355 "RABEPK,SERPINA3,TMEM74,SYT9,ACTN2,WLS,CLIP1,PLEKHG5,FCGR1A,FCGR1B,DISP3,AMPH,SGIP1,CNIH2,ITSN1,ANXA7,SH3GL2,APBA2,DGKD,SYBU,RPH3A,MADD,MSR1,MT3,CCDC88A,NSG2,CADPS,SCG3,CSPG5,LGI3,SNAP25,ATM,GABBR1,GAD2,ENKUR,ADAM15,KIF1B,GANAB,ACSBG1,MLC1,ABCC8,VAMP1,SYT4,GNAS,NRGN,HAP1,AZIN2,CAMK2A,CAMK2G,SYT6,NUCB1,GRIA1,GRIA2,GRIA4,RFFL,GRIN1,ATP13A2,TF,SPX,LEFTY2,CDC42,PCSK2,PDE4B,CHGA,NLGN3,SERPINE2,CADM1,NRXN1,CAMKV,FLRT1,PACSIN1,SNCAIP,FMN2,CALY,RAB39A,NRSN1,ECE2,SYTL2,SPIRE1,PTCH1,ITGAV,CNIH3,BLOC1S6,KCNA1,SV2A,KCNJ4,KCNK1,RAB5B,DNM2,SLC17A6,GOPC,VANGL2,SSPN,SH3GLB1" GO: Cellular Component GO:0097708 intracellular vesicle 8.02E-05 5.48E-02 7.71E-04 5.48E-03 94 1357 "RABEPK,SERPINA3,TMEM74,SYT9,ACTN2,WLS,CLIP1,PLEKHG5,FCGR1A,FCGR1B,DISP3,AMPH,SGIP1,CNIH2,ITSN1,ANXA7,SH3GL2,APBA2,DGKD,SYBU,RPH3A,MADD,MSR1,MT3,CCDC88A,NSG2,CADPS,SCG3,CSPG5,LGI3,SNAP25,ATM,GABBR1,GAD2,ENKUR,ADAM15,KIF1B,GANAB,ACSBG1,MLC1,ABCC8,VAMP1,SYT4,GNAS,NRGN,HAP1,AZIN2,CAMK2A,CAMK2G,SYT6,NUCB1,GRIA1,GRIA2,GRIA4,RFFL,GRIN1,ATP13A2,TF,SPX,LEFTY2,CDC42,PCSK2,PDE4B,CHGA,NLGN3,SERPINE2,CADM1,NRXN1,CAMKV,FLRT1,PACSIN1,SNCAIP,FMN2,CALY,RAB39A,NRSN1,ECE2,SYTL2,SPIRE1,PTCH1,ITGAV,CNIH3,BLOC1S6,KCNA1,SV2A,KCNJ4,KCNK1,RAB5B,DNM2,SLC17A6,GOPC,VANGL2,SSPN,SH3GLB1" GO: Cellular Component GO:0016323 basolateral plasma membrane 8.35E-05 5.70E-02 7.92E-04 5.63E-03 26 244 "ADORA1,ANK1,ANK2,ANK3,AQP4,SLC8A2,SLC14A1,MEGF11,ERBIN,AJAP1,MLC1,DDR1,TF,TJP1,SLC22A6,CADM1,BEST1,P2RY12,KCNJ4,KCNJ10,DLG2,DLG3,RASGRF1,VANGL2,PIANP,SLC4A10" GO: Cellular Component GO:0099501 exocytic vesicle membrane 1.09E-04 7.47E-02 1.01E-03 7.17E-03 11 61 "SYT9,AMPH,RPH3A,GAD2,ABCC8,VAMP1,SYT4,SYT6,GRIA2,SV2A,SLC17A6" GO: Cellular Component GO:0030672 synaptic vesicle membrane 1.09E-04 7.47E-02 1.01E-03 7.17E-03 11 61 "SYT9,AMPH,RPH3A,GAD2,ABCC8,VAMP1,SYT4,SYT6,GRIA2,SV2A,SLC17A6" GO: Cellular Component GO:0044433 cytoplasmic vesicle part 1.30E-04 8.85E-02 1.18E-03 8.38E-03 50 619 "SERPINA3,SYT9,ACTN2,WLS,CLIP1,FCGR1A,FCGR1B,DISP3,AMPH,SGIP1,CNIH2,ANXA7,SH3GL2,RPH3A,MSR1,NSG2,CADPS,SCG3,CSPG5,GAD2,KIF1B,ABCC8,VAMP1,SYT4,NRGN,CAMK2A,CAMK2G,SYT6,GRIA1,GRIA2,GRIA4,TF,LEFTY2,PCSK2,CHGA,CAMKV,FLRT1,PACSIN1,FMN2,CALY,RAB39A,ECE2,SPIRE1,PTCH1,CNIH3,SV2A,KCNJ4,DNM2,SLC17A6,GOPC" GO: Cellular Component GO:0070161 anchoring junction 2.19E-04 1.50E-01 1.97E-03 1.40E-02 42 503 "RPL38,ACTN2,ATAT1,FHL1,PPFIA1,PKP4,APC,SORBS1,PALLD,USP33,CADM3,ADAM15,NFASC,CLASP2,RND1,AJAP1,ARHGEF7,KAZN,DDR2,TJP1,CD81,CDC42,TNS1,TPM4,MAGI1,ZNF384,HNRNPK,ARHGAP22,CADM1,TJP2,FLRT1,DOCK7,CTNND1,CTNND2,ITGAV,CADM2,DNM2,L1CAM,NUP214,PIANP,ABI2,EPB41L2" Mouse Phenotype MP:0003635 abnormal synaptic transmission 1.73E-27 9.10E-24 9.10E-24 8.32E-23 129 773 "MAG,EPS8,MAP6,ASIC1,MAPT,MBP,ADGRV1,DSCAML1,ADCYAP1R1,FABP7,ADORA1,GPR158,SCN4B,LRRTM4,LRRC7,FGF14,SEMA6A,ELMOD1,CNIH2,SH3GL2,APBA2,SLITRK3,BCAN,NLGN1,CLSTN1,MADD,SLC6A9,SLC8A2,SLC8A3,CCDC88A,SHANK2,CADPS,CSPG5,SORCS3,B3GAT1,TMEM108,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,TNIK,GAD2,JPH4,ARPP21,LHFPL4,STARD10,CPLX2,DNER,NPAS3,NCAM1,GFAP,GFRA1,NCDN,DCLK2,WWC1,CACNA1A,ATF7,CACNA1E,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,SHISA7,CCKBR,PTPN5,PAX6,TNFRSF1B,IGSF21,PCDH9,CDH8,HRH3,SEZ6L,LGI1,PRMT8,PDE4B,NTSR2,ACOT7,CHRM1,CHRM4,CHRNB2,NLGN3,DLGAP3,SERPINE2,NRXN1,NRXN2,PACSIN1,CRMP1,KCNT2,NCAN,PRKACB,CALY,PRKCG,CTNND2,DPYSL5,ANKS1B,SIRPA,CNIH3,LRP8,KCNA1,KCNA2,PTPRE,PLPPR4,PTPRZ1,SV2A,SRGAP3,KCNJ9,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,OLIG1,SLC17A6,DPP6,RASGRF1,L1CAM,RET,EEF1A2,CACNG7,EFNA3,EN2,OLIG2,SEZ6" Mouse Phenotype MP:0003633 abnormal nervous system physiology 8.22E-27 4.33E-23 2.16E-23 1.98E-22 233 1997 "MAG,EPS8,MAP6,ASIC1,MAPT,ACHE,APC2,MBP,CEND1,ADGRV1,NDRG2,F3,DSCAML1,SLITRK1,ADCYAP1R1,FABP7,ADORA1,GPR158,AGT,SCN4B,LRRTM4,PLA2G6,LRRC7,FGF14,SEMA6A,ACTL6B,ELMOD1,MOBP,FOXG1,MOG,AMPH,ANK3,CNIH2,ITSN1,ANXA7,SH3GL2,APBA2,GAS7,DGKD,SLITRK3,BCAN,NLGN1,ST8SIA1,CLSTN1,AQP4,SLC1A2,ZNF365,SLC1A6,MADD,SLC6A9,SLC8A2,SLC8A3,CCDC88A,SHANK2,CADPS,ASCL1,SCG3,CSPG5,SORCS3,ASTN1,B3GAT1,TMEM108,SNAP25,ATM,SNCB,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SOX1,TNIK,CADM3,SOX10,GAD2,JPH4,B4GALNT1,NKX6-2,ARPP21,LHFPL4,KIF1B,STARD10,CPLX2,DNER,NPAS3,NFASC,NCAM1,ERBIN,GFAP,GFRA1,NCDN,RCOR2,GJB1,NEUROD1,MLC1,NHLH1,DCLK2,ROBO3,GNG3,NODAL,MYRF,UNC5D,CNTN2,ADGRL3,WWC1,CACNA1A,GPM6B,ATF7,CACNA1E,GPR17,TCF12,NRDC,HAP1,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SHISA7,CCKBR,PTPN5,MFSD2A,INA,TJP1,AIFM1,PAH,CD81,PAX6,TNFRSF1B,IGSF21,TNR,PCDH9,CDH8,RBFOX2,HRH3,SEZ6L,LGI1,PRMT8,PDE4B,PIRT,PDYN,GPR37L1,HAPLN2,NTSR2,ACOT7,ADGRG1,ASIC3,CHRM1,CHRM4,CHRNB2,HPCA,HEPACAM,NLGN3,DLGAP3,SERPINE2,NRXN1,NRXN2,VAV2,PMP2,PACSIN1,ATCAY,CP,POU3F2,MED1,PNKD,CRMP1,TENM4,KCNT2,FEZ1,NCAN,PRKACB,CALY,PRKCG,CTNND2,MAPK8,MAPK10,DPYSL5,ANKS1B,TUBB2B,SIRPA,PTAFR,PTCH1,DNAJC6,ITGAV,CNIH3,LRP8,BLOC1S6,KCNA1,KCNA2,KCNA4,PTPRE,PLPPR4,KCNC1,PTPRO,PTPRZ1,SV2A,SRGAP3,KCNJ9,KCNJ10,KCNJ11,ARNT2,KCNK2,PCDH15,KCNMA1,KCNN3,PEX5,KCNQ2,DLG2,DLG3,KIF2A,OLIG1,SLC17A6,DPP6,DSCAM,RASGRF1,RTN4,L1CAM,RET,USH1C,RGS7,EEF1A2,CACNG7,EFNA3,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2,SEZ6" Mouse Phenotype MP:0002206 abnormal CNS synaptic transmission 2.18E-25 1.15E-21 3.82E-22 3.50E-21 116 681 "MAG,EPS8,MAP6,ASIC1,MAPT,MBP,ADGRV1,DSCAML1,ADCYAP1R1,FABP7,ADORA1,GPR158,SCN4B,LRRTM4,LRRC7,FGF14,SEMA6A,ELMOD1,CNIH2,SH3GL2,APBA2,SLITRK3,BCAN,NLGN1,CLSTN1,MADD,SLC6A9,SLC8A2,CCDC88A,SHANK2,CADPS,CSPG5,SORCS3,B3GAT1,TMEM108,SNAP25,ATP1A3,FYN,ATP2B2,GABBR1,TNIK,GAD2,JPH4,LHFPL4,STARD10,CPLX2,DNER,NPAS3,NCAM1,GFAP,NCDN,DCLK2,WWC1,CACNA1A,ATF7,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,SHISA7,CCKBR,PTPN5,PAX6,TNFRSF1B,IGSF21,PCDH9,CDH8,SEZ6L,LGI1,PDE4B,NTSR2,ACOT7,CHRM1,CHRM4,CHRNB2,NLGN3,DLGAP3,SERPINE2,NRXN1,NRXN2,PACSIN1,CRMP1,NCAN,PRKACB,CALY,PRKCG,CTNND2,DPYSL5,ANKS1B,SIRPA,CNIH3,LRP8,KCNA1,KCNA2,PLPPR4,PTPRZ1,SV2A,SRGAP3,KCNJ10,KCNMA1,KCNQ2,DLG2,DLG3,OLIG1,SLC17A6,DPP6,RASGRF1,L1CAM,CACNG7,EFNA3,OLIG2,SEZ6" Mouse Phenotype MP:0002882 abnormal neuron morphology 1.24E-16 6.54E-13 1.36E-13 1.24E-12 175 1581 "MAG,ACER3,MAP6,MAPT,APC2,MBP,LGR4,CEND1,ADGRV1,EYA1,MDM4,DSCAML1,GPR158,PLA2G6,LRRC7,FGF14,SEMA6A,ACTL6B,BCAR3,FOXG1,MOG,ANK1,ANK3,SH3GL2,APBB1,GAS7,SLITRK3,NLGN1,CLSTN1,SLC1A2,MADD,MSR1,CCDC88A,SHANK2,CADPS,ASCL1,SLIT1,ASTN1,TMEM108,ATM,ATP1A3,FYN,ATP2B2,MEGF11,GABBR1,SOX1,TNIK,KIF21B,SOX10,NMNAT2,B4GALNT1,NKX6-2,LHFPL4,KIF1B,NFASC,NCAM1,BCL2L2,SMOC1,ERBIN,GFAP,GFRA1,RCOR2,FGF17,KIRREL3,GJB1,NEUROD1,NFIA,MLC1,NHLH1,DCLK2,NKX2-2,SEMA4A,DDHD2,ROBO3,CAMTA1,CDK5R2,UNC5D,CNTN2,CACNA1A,GPM6A,GPM6B,CACNB2,ZEB1,NRDC,HAP1,PTBP2,CAMK2A,BRSK2,GRIA1,GRIA2,GRID1,GRIK4,GRIN1,ATP13A2,CRB1,MFSD2A,GUCY1A1,AIFM1,CD81,PAX6,IGSF21,TNR,PCDH9,CDH8,DCLK1,RBFOX2,PRMT8,PDE4B,GPR37L1,HAPLN2,ACOT7,ADGRG1,ASIC3,TUB,TLX1,JAM2,HPCA,HEPACAM,NLGN3,SEMA5B,CPT1C,VAV2,CNTN1,PMP2,PACSIN1,FAT3,ATCAY,CP,POU3F2,POU3F4,CRMP1,VCAN,RBPJ,PRKACB,CTNND1,HES5,PROX1,KLK6,DPYSL5,SPIRE1,SIRPA,PTCH1,DNAJC6,LRP8,MAGI2,SRGAP3,KCNJ10,PCDH15,KCNMA1,PEX5,DLG3,KIF2A,OLIG1,SLC17A6,DSCAM,DTNA,RTN4,PAK5,L1CAM,SLC6A15,CRTAC1,RET,USH1C,RFX4,EEF1A2,VANGL2,RLBP1,EFNA3,ABI2,ELAVL4,ROM1,EN2,OLIG2,RPE65,SEZ6" Mouse Phenotype MP:0002910 abnormal excitatory postsynaptic currents 1.29E-16 6.78E-13 1.36E-13 1.24E-12 40 143 "EPS8,DSCAML1,ADORA1,GPR158,SH3GL2,APBA2,NLGN1,CLSTN1,MADD,CCDC88A,CADPS,CSPG5,TMEM108,GABBR1,GAD2,CPLX2,DNER,CACNA1A,CAMK2A,GRIA2,GRIK4,GRIN1,SHISA7,CCKBR,SEZ6L,CHRM1,NLGN3,SERPINE2,NRXN1,NRXN2,PACSIN1,PRKCG,ANKS1B,PLPPR4,KCNJ10,DLG2,DLG3,SLC17A6,CACNG7,SEZ6" Mouse Phenotype MP:0002064 seizures 1.80E-15 9.46E-12 1.58E-12 1.44E-11 68 390 "MAG,MAPT,ACHE,APC2,MBP,ADGRV1,ADORA1,FGF14,AMPH,ANK3,SH3GL2,DGKD,SLITRK3,ST8SIA1,SLC1A2,SNAP25,ATP1A3,FYN,GABBR1,SOX1,SOX10,GAD2,B4GALNT1,GFAP,NCDN,GJB1,NEUROD1,DCLK2,GNG3,MYRF,CNTN2,CACNA1A,TCF12,CAMK2A,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,AIFM1,PAH,TNFRSF1B,LGI1,PDYN,CHRNB2,SERPINE2,PACSIN1,ATCAY,MAPK10,ITGAV,BLOC1S6,KCNA1,KCNA2,KCNA4,PLPPR4,KCNC1,PTPRO,SV2A,KCNJ9,KCNJ10,KCNJ11,KCNK2,KCNQ2,DSCAM,SLC4A10,ELAVL3,OLIG2,SEZ6" Mouse Phenotype MP:0002063 abnormal learning/memory/conditioning 1.26E-12 6.62E-09 8.00E-10 7.32E-09 92 703 "ASIC1,MAPT,MBP,CNTNAP3,ADCYAP1R1,FABP7,PLA2G6,LRRC7,FGF14,AMPH,ITSN1,APBA2,APBB1,SLC6A9,SLC8A2,CCDC88A,SHANK2,SORCS3,B3GAT1,TMEM108,SNAP25,ATM,ATP1A2,ATP1A3,FYN,GABBR1,TNIK,KIF21B,GAD2,JPH4,CPLX2,FXYD6,NPAS3,NCAM1,BCL2L2,GFAP,NCDN,SYT4,GNAS,DDHD2,WWC1,WSCD1,PRLHR,NRDC,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,ATP13A2,SHISA7,NEURL1,PAH,PCDH9,HRH3,PRMT8,PDE4B,PDYN,GPR37L1,CHRNB2,NLGN3,NRXN1,CPT1C,CRMP1,FEZ1,PRKACB,PRKCG,CTNND2,SPIRE1,SIRPA,LRP8,KCNC1,PTPRZ1,SRGAP3,KCNJ11,KCNMA1,NAV2,DLG3,OLIG1,SLC17A6,DSCAM,RASGRF1,PAK5,L1CAM,RGS7,EFNA3,ABI2,SLC4A10,EN2,RCAN2,SEZ6" Mouse Phenotype MP:0002886 abnormal glutamate-mediated receptor currents 1.35E-12 7.13E-09 8.00E-10 7.32E-09 24 70 "EPS8,FABP7,GPR158,CNIH2,CLSTN1,SLC6A9,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,SHISA7,TNFRSF1B,LGI1,NLGN3,DLGAP3,SERPINE2,NRXN1,NRXN2,CNIH3,SLC17A6,CACNG7,EFNA3" Mouse Phenotype MP:0014114 abnormal cognition 1.37E-12 7.20E-09 8.00E-10 7.32E-09 92 704 "ASIC1,MAPT,MBP,CNTNAP3,ADCYAP1R1,FABP7,PLA2G6,LRRC7,FGF14,AMPH,ITSN1,APBA2,APBB1,SLC6A9,SLC8A2,CCDC88A,SHANK2,SORCS3,B3GAT1,TMEM108,SNAP25,ATM,ATP1A2,ATP1A3,FYN,GABBR1,TNIK,KIF21B,GAD2,JPH4,CPLX2,FXYD6,NPAS3,NCAM1,BCL2L2,GFAP,NCDN,SYT4,GNAS,DDHD2,WWC1,WSCD1,PRLHR,NRDC,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,ATP13A2,SHISA7,NEURL1,PAH,PCDH9,HRH3,PRMT8,PDE4B,PDYN,GPR37L1,CHRNB2,NLGN3,NRXN1,CPT1C,CRMP1,FEZ1,PRKACB,PRKCG,CTNND2,SPIRE1,SIRPA,LRP8,KCNC1,PTPRZ1,SRGAP3,KCNJ11,KCNMA1,NAV2,DLG3,OLIG1,SLC17A6,DSCAM,RASGRF1,PAK5,L1CAM,RGS7,EFNA3,ABI2,SLC4A10,EN2,RCAN2,SEZ6" Mouse Phenotype MP:0009745 abnormal behavioral response to xenobiotic 8.79E-12 4.63E-08 4.63E-09 4.24E-08 52 303 "EPS8,MAP6,MAPT,MBP,RYR1,SCN4B,FGF14,UNC79,AMPH,SLITRK3,AQP4,SLC1A2,SLC6A9,ATP1A3,FYN,GAD2,NPAS3,GFAP,NCDN,GLS,GNAS,CNTN2,ADGRL3,CACNA1A,PRLHR,GPR26,GRIA1,GRIA4,GRIK2,GRIK4,GRIN1,CCKBR,AIFM1,CD81,LGI1,PDYN,CHRM4,CHRNB2,DLGAP3,SERPINE2,PRKCG,MAPK10,ANKS1B,KCNA1,KCNA2,KCNC1,PTPRO,KCNK2,KCNQ2,SLC17A6,SLC4A10,SEZ6" Mouse Phenotype MP:0001392 abnormal locomotor behavior 1.17E-11 6.17E-08 5.60E-09 5.13E-08 160 1581 "MAG,ACER3,MAP6,MAPT,ACHE,APC2,MBP,CEND1,F3,SLITRK1,ADCYAP1R1,RYR1,FABP7,AGT,SCN3A,PLA2G6,LRRC7,FGF14,ACTL6B,UNC79,ELMOD1,FOXG1,MOG,SGIP1,ANK3,SH3GL2,APBA2,APC,CLSTN1,SLC1A2,MSRA,SLC6A9,CCDC88A,SHANK2,SNAP25,ATM,ATP1A2,ATP1A3,FYN,ATP2B2,DKK3,GABBR1,SOX1,B3GALT2,TNIK,SOX10,GAD2,JPH4,B4GALNT1,KIF1B,STARD10,CPLX2,ADGRB2,NPAS3,NFASC,BCL2L2,NDUFA5,SMOC1,NCDN,FGF17,GJB1,NEUROD1,MLC1,GLS,VAMP1,GNAS,DDHD2,ROBO3,CAMTA1,MYRF,ADGRL3,CACNA1A,GPM6B,DDR1,TCF7L2,ZEB1,HAP1,CAMK2A,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,GRIN1,ATP13A2,CCKBR,USP2,MFSD2A,AIFM1,NEURL1,PAH,ATG4C,CD81,TNFRSF1B,PCDH9,RBFOX2,HRH3,SEZ6L,LGI1,PRMT8,PDE4B,PDYN,GPR37L1,NTSR2,ACOT7,ADGRG1,CHRM1,CHRM4,CHRNB2,NLGN3,NRXN1,NRXN2,NEGR1,FTO,CNTN1,ATCAY,CP,POU3F4,PPP3CB,FEZ1,RBPJ,PRKAB2,PROX1,ANKS1B,TUBB2B,PTCH1,ITGAV,PTHLH,LRP8,BLOC1S6,KCNA1,KCNA2,KCNC1,KCNH1,SRGAP3,KCNJ10,KCNJ11,PCDH15,KCNMA1,PEX5,DLG3,OLIG1,SLC17A6,ATN1,DSCAM,PAK5,L1CAM,RET,USH1C,RGS7,ATL1,VANGL2,CACNG7,EFNA3,BSCL2,EN2,OLIG2,RPE65,RCAN2,SEZ6" Mouse Phenotype MP:0008540 abnormal cerebral hemisphere morphology 1.82E-11 9.59E-08 7.80E-09 7.14E-08 84 645 "MAPT,ACHE,APC2,MBP,ATAT1,FABP7,DRAXIN,AGT,LRRTM4,FGF1,FGF14,SEMA6A,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,BCAN,SLC1A2,ARHGAP5,CCDC88A,CADPS,TMEM108,SNAP25,ATM,ATP1A3,FYN,ATP2B2,SOX1,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,RCOR2,NEUROD1,NFIA,MLC1,DCLK2,CDK5R2,CNTN2,GPM6B,NRDC,HAP1,PTBP2,CAMK2A,BRSK2,GRIA2,GRIN1,AIFM1,PAH,CD81,PAX6,TNR,PCDH9,DCLK1,LGI1,ADGRG1,CHRM1,HPCA,CADM1,PACSIN1,POU3F2,CRMP1,CTNND1,MAPK8,PROX1,TUBB2B,LRP8,KCNA1,KCNJ10,PEX5,KCNQ2,DLG3,KIF2A,OLIG1,DSCAM,L1CAM,RFX4,VANGL2,EFNA3,ABI2,OLIG2" Mouse Phenotype MP:0003491 abnormal voluntary movement 1.93E-11 1.01E-07 7.80E-09 7.14E-08 168 1698 "MAG,ACER3,MAP6,MAPT,ACHE,APC2,MBP,CEND1,EYA1,F3,SLITRK1,ADCYAP1R1,RYR1,FABP7,AGT,SCN3A,PLA2G6,LRRC7,FGF14,ACTL6B,UNC79,ELMOD1,FOXG1,MOG,SGIP1,ANK3,SH3GL2,APBA2,APC,CLSTN1,SLC1A2,MSRA,SLC6A9,CCDC88A,SHANK2,DLL3,SNAP25,ATM,ATP1A2,ATP1A3,FYN,ATP2B2,DKK3,GABBR1,SOX1,B3GALT2,TNIK,SOX10,GAD2,NMNAT2,JPH4,B4GALNT1,KIF1B,STARD10,CPLX2,ADGRB2,NPAS3,NFASC,BCL2L2,NDUFA5,SMOC1,NCDN,FGF17,GJB1,NEUROD1,MLC1,GLS,VAMP1,POPDC3,GNAS,DDHD2,ROBO3,CAMTA1,MYRF,ADGRL3,CACNA1A,GPM6B,DDR1,TCF7L2,ZEB1,HAP1,PTBP2,CAMK2A,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,GRIN1,ATP13A2,CCKBR,USP2,MFSD2A,AIFM1,NEURL1,PAH,ATG4C,CD81,TNFRSF1B,PCDH9,CDH8,RBFOX2,HRH3,SEZ6L,LGI1,PRMT8,PDE4B,PDYN,GPR37L1,NTSR2,ACOT7,ADGRG1,CHRM1,CHRM4,CHRNB2,NLGN3,CADM1,NRXN1,NRXN2,NEGR1,FTO,CNTN1,ATCAY,CP,POU3F4,TENM4,PPP3CB,FEZ1,RBPJ,PRKAB2,PROX1,ANKS1B,TUBB2B,PTCH1,ITGAV,PTHLH,LRP8,BLOC1S6,KCNA1,KCNA2,KCNC1,KCNH1,SRGAP3,KCNJ10,KCNJ11,PCDH15,KCNMA1,PEX5,DLG3,OLIG1,SLC17A6,ATN1,DSCAM,PAK5,L1CAM,RET,USH1C,RGS7,ATL1,VANGL2,CACNG7,EFNA3,BSCL2,EN2,OLIG2,RPE65,RCAN2,SEZ6" Mouse Phenotype MP:0002152 abnormal brain morphology 2.21E-11 1.17E-07 8.33E-09 7.62E-08 172 1755 "RPL38,ACER3,MAPT,ACHE,APC2,MBP,CEND1,EYA1,ATAT1,ARID1A,WLS,MDM4,F3,RXRG,FABP7,DRAXIN,AGT,LRRTM4,FGF1,PLA2G6,FGF14,SEMA6A,BBOX1,SLC30A10,FOXG1,ANK1,ANK3,ITSN1,SH3GL2,APBB1,APC,BCAN,SLC1A2,ZNF365,ARHGAP5,CCDC88A,SHANK2,CADPS,ASCL1,SLIT1,DLL3,ASTN1,TMEM108,SNAP25,ATM,SNCB,ATP1A2,ATP1A3,FYN,ATP2B2,PALLD,SOX1,TNIK,SOX10,NMNAT2,B4GALNT1,NKX6-2,KIF1B,CPLX2,DNER,NPAS3,NFASC,NCAM1,BCL2L2,GFAP,NCDN,RCOR2,FGF17,KIRREL3,NEUROD1,NFIA,MLC1,DCLK2,NKX2-2,GNAS,DDHD2,ROBO3,CAMTA1,NODAL,CDK5R2,CNTN2,CACNA1A,GPM6B,CACNB2,TCF7L2,ZEB1,TCF12,NRDC,HAP1,PTBP2,CAMK2A,CECR2,DDR2,BRSK2,GRIA2,GRIN1,TIE1,AIFM1,PAH,CD81,PAX6,TNR,PCDH9,DCLK1,RBFOX2,LGI1,PRMT8,PDE4B,PDYN,GPR37L1,ADGRG1,ASIC3,CHRM1,TUB,CHRNB2,HPCA,HEPACAM,NLGN3,DLGAP3,SERPINE2,CADM1,VAV2,CNTN1,PACSIN1,ATCAY,CP,POU3F2,MED1,CRMP1,ATRNL1,PRKACB,IGSF1,CTNND1,MAPK8,HES5,PROX1,DPYSL5,TUBB2B,PTCH1,ITGAV,PTHLH,LRP8,RGMA,KCNA1,PLPPR4,SRGAP3,KCNJ10,ARNT2,PEX5,KCNQ2,DLG3,KIF2A,OLIG1,DNM2,SLC17A6,ATG16L1,ABI1,DSCAM,L1CAM,CRTAC1,RET,RFX4,EEF1A2,VANGL2,EFNA3,ABI2,SLC4A10,EN2,OLIG2,TMEM100,EPB41L1,EPB41L2" Mouse Phenotype MP:0002915 abnormal synaptic depression 3.63E-11 1.91E-07 1.27E-08 1.17E-07 31 130 "MAPT,ADORA1,SCN4B,LRRC7,SH3GL2,SLC8A2,SHANK2,CSPG5,SORCS3,NCAM1,GFAP,NCDN,WWC1,CAMK2A,GRIA1,GRIA2,GRIN1,PDE4B,CHRM1,CHRM4,NLGN3,NRXN1,NRXN2,PACSIN1,PRKACB,CALY,DPYSL5,ANKS1B,SV2A,KCNMA1,SLC17A6" Mouse Phenotype MP:0000801 abnormal temporal lobe morphology 4.25E-11 2.24E-07 1.40E-08 1.28E-07 58 375 "MAPT,APC2,ATAT1,FABP7,AGT,LRRTM4,FGF14,SEMA6A,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,BCAN,SLC1A2,CCDC88A,CADPS,TMEM108,SNAP25,ATP1A3,FYN,ATP2B2,SOX1,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,NEUROD1,NFIA,DCLK2,CDK5R2,PTBP2,CAMK2A,BRSK2,GRIA2,CD81,PAX6,TNR,DCLK1,LGI1,CHRM1,HPCA,CADM1,PACSIN1,CRMP1,CTNND1,PROX1,LRP8,KCNA1,KCNQ2,KIF2A,DSCAM,L1CAM,VANGL2,EFNA3,ABI2" Mouse Phenotype MP:0001516 abnormal motor coordination/balance 5.58E-11 2.94E-07 1.73E-08 1.58E-07 101 858 "MAG,EPS8,ACER3,MAPT,ACHE,APC2,MBP,CEND1,F3,PLA2G6,FGF14,MOG,ANK1,ANK3,ITSN1,PKP4,SH3GL2,APBA2,GAS7,SLC8A3,SHANK2,ASTN1,SNAP25,ATM,ATP1A3,ATP2B2,B3GALT2,SOX10,B4GALNT1,NKX6-2,SALL3,KIF1B,CPLX2,DNER,NPAS3,NFASC,BCL2L2,NDUFA5,NCDN,GJB1,NEUROD1,MLC1,VAMP1,SYT4,GNAS,DDHD2,ROBO3,CAMTA1,MYRF,CACNA1A,GPM6B,NRDC,HAP1,CAMK2A,GRIA2,GRIA4,GRIN1,ATP13A2,CCKBR,MFSD2A,AIFM1,PAH,PCDH9,RBFOX2,SEZ6L,GPR37L1,ACOT7,CHRNB2,NLGN3,CNTN1,ATCAY,CP,POU3F4,CTNND2,MAPK10,PTCH1,ITGAV,LRP8,BLOC1S6,KCNA1,KCNA2,KCNC1,PTPRZ1,KCNJ10,KCNJ11,PCDH15,KCNMA1,PEX5,SLC17A6,DSCAM,DTNA,L1CAM,USH1C,EEF1A2,VANGL2,CACNG7,ELAVL3,ELAVL4,EN2,OLIG2,SEZ6" Mouse Phenotype MP:0008415 abnormal neurite morphology 6.83E-11 3.60E-07 2.00E-08 1.83E-07 65 452 "MAG,MAPT,MBP,CEND1,GPR158,PLA2G6,LRRC7,SEMA6A,ACTL6B,ANK3,SH3GL2,NLGN1,CLSTN1,CCDC88A,SHANK2,CADPS,SLIT1,TMEM108,ATM,GABBR1,KIF21B,SOX10,NMNAT2,NFASC,NCAM1,BCL2L2,ERBIN,GJB1,MLC1,CACNA1A,GPM6B,NRDC,HAP1,CAMK2A,GRIA1,GRIK4,PCDH9,DCLK1,PRMT8,PDE4B,HAPLN2,JAM2,HEPACAM,NLGN3,SEMA5B,CPT1C,CNTN1,PMP2,POU3F2,CRMP1,VCAN,DPYSL5,SPIRE1,SRGAP3,PEX5,DLG3,KIF2A,OLIG1,SLC17A6,DSCAM,PAK5,L1CAM,RET,OLIG2,SEZ6" Mouse Phenotype MP:0000787 abnormal telencephalon morphology 1.03E-10 5.41E-07 2.85E-08 2.60E-07 101 867 "RPL38,MAPT,ACHE,APC2,MBP,ATAT1,MDM4,RXRG,FABP7,DRAXIN,AGT,LRRTM4,FGF1,FGF14,SEMA6A,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,APC,BCAN,SLC1A2,ARHGAP5,CCDC88A,CADPS,ASCL1,SLIT1,TMEM108,SNAP25,ATM,SNCB,ATP1A2,ATP1A3,FYN,ATP2B2,SOX1,SOX10,NMNAT2,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,RCOR2,KIRREL3,NEUROD1,NFIA,MLC1,DCLK2,CDK5R2,CNTN2,GPM6B,ZEB1,NRDC,HAP1,PTBP2,CAMK2A,BRSK2,GRIA2,GRIN1,AIFM1,PAH,CD81,PAX6,TNR,PCDH9,DCLK1,LGI1,ADGRG1,CHRM1,HPCA,DLGAP3,CADM1,PACSIN1,POU3F2,MED1,CRMP1,CTNND1,MAPK8,HES5,PROX1,TUBB2B,PTCH1,LRP8,KCNA1,KCNJ10,PEX5,KCNQ2,DLG3,KIF2A,OLIG1,DSCAM,L1CAM,CRTAC1,RFX4,VANGL2,EFNA3,ABI2,OLIG2" Mouse Phenotype MP:0002207 abnormal long term potentiation 1.12E-10 5.88E-07 2.94E-08 2.69E-07 43 238 "ASIC1,MAPT,ADCYAP1R1,FGF14,CNIH2,BCAN,CLSTN1,SLC8A2,CCDC88A,SHANK2,B3GAT1,FYN,GABBR1,JPH4,CPLX2,NCAM1,GFAP,NCDN,WWC1,CAMK2A,GRIA1,GRIA2,GRIK2,GRIK3,GRIK4,GRIN1,SHISA7,PDE4B,SERPINE2,CRMP1,NCAN,PRKACB,PRKCG,CTNND2,SIRPA,CNIH3,LRP8,PTPRZ1,KCNJ10,DLG3,DPP6,RASGRF1,EFNA3" Mouse Phenotype MP:0004166 abnormal limbic system morphology 1.24E-10 6.52E-07 3.11E-08 2.84E-07 61 416 "MAPT,APC2,ATAT1,FABP7,AGT,LRRTM4,FGF14,SEMA6A,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,BCAN,SLC1A2,CCDC88A,CADPS,TMEM108,SNAP25,ATP1A2,ATP1A3,FYN,SOX1,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,NEUROD1,NFIA,DCLK2,CDK5R2,HAP1,PTBP2,CAMK2A,BRSK2,GRIA2,CD81,PAX6,TNR,DCLK1,LGI1,TUB,HPCA,CADM1,PACSIN1,POU3F2,CRMP1,CTNND1,PROX1,LRP8,KCNA1,ARNT2,KCNQ2,KIF2A,DSCAM,L1CAM,VANGL2,EFNA3,ABI2" Mouse Phenotype MP:0000783 abnormal forebrain morphology 1.47E-10 7.76E-07 3.53E-08 3.23E-07 119 1095 "RPL38,MAPT,ACHE,APC2,MBP,EYA1,ATAT1,ARID1A,WLS,MDM4,F3,RXRG,FABP7,DRAXIN,AGT,LRRTM4,FGF1,FGF14,SEMA6A,BBOX1,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,APC,BCAN,SLC1A2,ARHGAP5,CCDC88A,CADPS,ASCL1,SLIT1,TMEM108,SNAP25,ATM,SNCB,ATP1A2,ATP1A3,FYN,ATP2B2,SOX1,SOX10,NMNAT2,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,RCOR2,KIRREL3,NEUROD1,NFIA,MLC1,DCLK2,NODAL,CDK5R2,CNTN2,GPM6B,TCF7L2,ZEB1,NRDC,HAP1,PTBP2,CAMK2A,CECR2,DDR2,BRSK2,GRIA2,GRIN1,TIE1,AIFM1,PAH,CD81,PAX6,TNR,PCDH9,DCLK1,LGI1,ADGRG1,CHRM1,TUB,CHRNB2,HPCA,DLGAP3,CADM1,PACSIN1,ATCAY,POU3F2,MED1,CRMP1,IGSF1,CTNND1,MAPK8,HES5,PROX1,TUBB2B,PTCH1,PTHLH,LRP8,KCNA1,KCNJ10,ARNT2,PEX5,KCNQ2,DLG3,KIF2A,OLIG1,SLC17A6,DSCAM,L1CAM,CRTAC1,RFX4,VANGL2,EFNA3,ABI2,OLIG2,TMEM100" Mouse Phenotype MP:0002912 abnormal excitatory postsynaptic potential 1.72E-10 9.03E-07 3.93E-08 3.59E-07 27 107 "ASIC1,MAPT,ADORA1,LRRTM4,CLSTN1,SHANK2,FYN,TNIK,JPH4,GFAP,CACNA1A,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,CHRM1,NLGN3,DLGAP3,SERPINE2,SIRPA,PLPPR4,DLG2,RASGRF1,EFNA3,OLIG2,SEZ6" Mouse Phenotype MP:0000807 abnormal hippocampus morphology 2.00E-10 1.05E-06 4.38E-08 4.01E-07 56 369 "MAPT,APC2,ATAT1,FABP7,AGT,LRRTM4,FGF14,SEMA6A,FOXG1,ANK3,ITSN1,SH3GL2,APBB1,BCAN,SLC1A2,CCDC88A,CADPS,TMEM108,SNAP25,ATP1A3,FYN,SOX1,KIF1B,CPLX2,NPAS3,NCAM1,GFAP,NCDN,NEUROD1,NFIA,DCLK2,CDK5R2,PTBP2,CAMK2A,BRSK2,GRIA2,CD81,PAX6,TNR,DCLK1,LGI1,HPCA,CADM1,PACSIN1,CRMP1,CTNND1,PROX1,LRP8,KCNA1,KCNQ2,KIF2A,DSCAM,L1CAM,VANGL2,EFNA3,ABI2" Mouse Phenotype MP:0003313 abnormal locomotor activation 2.72E-10 1.43E-06 5.74E-08 5.25E-07 125 1182 "MAG,ACER3,MAP6,MAPT,MBP,SLITRK1,ADCYAP1R1,RYR1,FABP7,AGT,SCN3A,PLA2G6,LRRC7,FGF14,ACTL6B,UNC79,ELMOD1,FOXG1,MOG,SGIP1,ANK3,SH3GL2,APBA2,APC,CLSTN1,SLC1A2,SLC6A9,CCDC88A,SHANK2,SNAP25,ATM,ATP1A2,ATP1A3,ATP2B2,DKK3,GABBR1,SOX1,B3GALT2,TNIK,GAD2,JPH4,KIF1B,STARD10,CPLX2,ADGRB2,NPAS3,NFASC,BCL2L2,NDUFA5,NCDN,NEUROD1,GLS,VAMP1,GNAS,DDHD2,ADGRL3,CACNA1A,DDR1,TCF7L2,ZEB1,HAP1,CAMK2A,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,GRIN1,ATP13A2,CCKBR,USP2,MFSD2A,AIFM1,ATG4C,CD81,TNFRSF1B,PCDH9,RBFOX2,HRH3,SEZ6L,LGI1,PRMT8,PDE4B,PDYN,GPR37L1,ACOT7,CHRM1,CHRM4,CHRNB2,NLGN3,NRXN1,NRXN2,NEGR1,FTO,ATCAY,CP,PPP3CB,FEZ1,RBPJ,PRKAB2,PROX1,ANKS1B,TUBB2B,KCNC1,KCNH1,SRGAP3,KCNJ10,KCNJ11,PCDH15,DLG3,OLIG1,SLC17A6,PAK5,L1CAM,RET,USH1C,RGS7,VANGL2,EFNA3,BSCL2,EN2,OLIG2,RPE65,RCAN2,SEZ6" Mouse Phenotype MP:0002062 abnormal associative learning 1.24E-09 6.52E-06 2.51E-07 2.29E-06 49 315 "ASIC1,MAPT,ADCYAP1R1,FABP7,FGF14,AMPH,ITSN1,APBB1,SLC6A9,SLC8A2,CCDC88A,SORCS3,TMEM108,ATP1A3,FYN,GABBR1,KIF21B,GAD2,JPH4,FXYD6,NPAS3,GFAP,SYT4,WWC1,PRLHR,CAMK2A,GRIA1,GRIA2,GRIK2,GRIN1,SHISA7,PDE4B,PDYN,CHRNB2,NLGN3,FEZ1,PRKACB,PRKCG,CTNND2,SPIRE1,LRP8,PTPRZ1,SRGAP3,KCNMA1,SLC17A6,RASGRF1,PAK5,EFNA3,ABI2" Mouse Phenotype MP:0001463 abnormal spatial learning 1.47E-09 7.76E-06 2.87E-07 2.63E-06 42 248 "ASIC1,MAPT,MBP,FGF14,AMPH,ITSN1,APBB1,SLC6A9,SLC8A2,CCDC88A,SHANK2,SORCS3,B3GAT1,SNAP25,ATP1A2,ATP1A3,FYN,KIF21B,CPLX2,NCAM1,NCDN,DDHD2,WWC1,CAMK2A,GRIA2,GRIN1,ATP13A2,HRH3,CHRNB2,NLGN3,CPT1C,CRMP1,PRKCG,CTNND2,LRP8,PTPRZ1,DLG3,SLC17A6,RASGRF1,L1CAM,EN2,SEZ6" Mouse Phenotype MP:0000953 abnormal oligodendrocyte morphology 1.95E-09 1.03E-05 3.67E-07 3.36E-06 19 61 "MAG,MBP,MOG,ZNF365,SOX10,GFAP,GJB1,NKX2-2,MYRF,GPM6B,GPR17,TENM4,HES5,KLK6,PTPRZ1,KCNJ10,PEX5,OLIG1,OLIG2" Mouse Phenotype MP:0009357 abnormal seizure response to inducing agent 2.10E-09 1.10E-05 3.81E-07 3.48E-06 36 195 "MAPT,MBP,ADGRV1,ADORA1,FGF14,AMPH,SLITRK3,ST8SIA1,SLC1A2,ATP1A3,FYN,GABBR1,GAD2,B4GALNT1,GFAP,GNG3,CNTN2,CACNA1A,GRIA4,GRIK2,GRIK4,GRIN1,AIFM1,PAH,LGI1,PDYN,CHRNB2,SERPINE2,MAPK10,KCNA1,KCNA2,PTPRO,KCNK2,KCNQ2,SLC4A10,SEZ6" Mouse Phenotype MP:0002067 abnormal sensory capabilities/reflexes/nociception 2.84E-09 1.50E-05 4.99E-07 4.56E-06 104 957 "MAG,EPS8,ACER3,MAPT,ACHE,MBP,ADGRV1,SLITRK1,RYR1,ADORA1,ADORA3,KIAA1109,LRRC7,FGF14,ELMOD1,MOG,SEMA6C,SGIP1,PKP4,MADD,SLC6A9,SLC8A3,SHANK2,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SOX1,B3GALT2,SOX10,JPH4,B4GALNT1,SALL3,KIF1B,CPLX2,NPAS3,NDUFA5,SMOC1,ERBIN,NELL1,AJAP1,VAMP1,NHLH1,GNAS,ROBO3,CDK5R2,CACNA1A,ATF7,CACNA1E,PRLHR,ZEB1,NRDC,BRSK2,GRIA1,GRIA2,GRIA4,GRIK4,GRIN1,ATP13A2,CCKBR,USP2,P2RX7,PAH,PAX6,PCDH9,CDH8,PCSK2,PRMT8,PIRT,PDYN,NTSR2,ADGRG1,ASIC3,CHRNB2,NLGN3,SERPINE2,CPT1C,PMP2,ATCAY,POU3F4,KCNT2,PRKCG,ARHGEF4,DPYSL5,KCNA1,KCNA2,KCNA6,PTPRZ1,KCNJ10,PCDH15,KCNMA1,NAV2,DLG2,SLC17A6,ATN1,L1CAM,USH1C,EFNA3,ELAVL4,EN2,OLIG2,RPE65" Mouse Phenotype MP:0001405 impaired coordination 3.29E-09 1.73E-05 5.58E-07 5.11E-06 63 473 "MAG,ACER3,MAPT,APC2,MBP,CEND1,PLA2G6,FGF14,ITSN1,SH3GL2,GAS7,SLC8A3,SHANK2,ASTN1,SNAP25,ATM,ATP1A3,ATP2B2,B3GALT2,SOX10,B4GALNT1,NKX6-2,KIF1B,CPLX2,DNER,NPAS3,NFASC,NDUFA5,NCDN,GJB1,SYT4,DDHD2,ROBO3,CAMTA1,CACNA1A,NRDC,GRIA2,GRIN1,CCKBR,AIFM1,PCDH9,RBFOX2,SEZ6L,ACOT7,NLGN3,CP,CTNND2,MAPK10,ITGAV,KCNA2,KCNC1,PTPRZ1,KCNJ11,PCDH15,KCNMA1,SLC17A6,DTNA,L1CAM,EEF1A2,ELAVL3,ELAVL4,EN2,SEZ6" Mouse Phenotype MP:0003492 abnormal involuntary movement 4.93E-09 2.60E-05 8.11E-07 7.42E-06 103 954 "MAG,EPS8,ACER3,MAPT,ACHE,MBP,ADGRV1,SLITRK1,RYR1,KIAA1109,PLA2G6,LRRC7,FGF14,ELMOD1,MOG,SGIP1,ANK1,ANK3,PKP4,MIER1,MADD,SLC6A9,SLC8A3,SHANK2,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SOX1,B3GALT2,SOX10,JPH4,B4GALNT1,SALL3,KIF1B,CPLX2,NPAS3,NDUFA5,SMOC1,ERBIN,NELL1,GJB1,AJAP1,NFIA,VAMP1,NHLH1,GNAS,ROBO3,MYRF,CDK5R2,CACNA1A,GPM6B,ATF7,ZEB1,NRDC,BRSK2,GRIA2,GRIA4,GRIK4,GRIN1,ATP13A2,CCKBR,USP2,AIFM1,PAX6,PCSK2,PRMT8,PDYN,NTSR2,ASIC3,CHRNB2,NLGN3,NRXN1,CPT1C,PMP2,ATCAY,POU3F4,TENM4,ARHGEF4,DPYSL5,ITGAV,LRP8,KCNA1,KCNA2,KCNC1,KCNJ10,PCDH15,KCNMA1,NAV2,PEX5,DLG2,SLC17A6,ATN1,L1CAM,USH1C,EEF1A2,EFNA3,ELAVL4,EN2,OLIG2,RPE65" Mouse Phenotype MP:0000947 convulsive seizures 7.73E-09 4.07E-05 1.23E-06 1.13E-05 33 177 "MAG,MBP,ADGRV1,AMPH,ANK3,ST8SIA1,SLC1A2,SNAP25,ATP1A3,FYN,GABBR1,GAD2,B4GALNT1,GJB1,NEUROD1,DCLK2,GNG3,CACNA1A,GRIA2,GRIK4,GRIN1,PAH,LGI1,PACSIN1,ITGAV,BLOC1S6,KCNA1,KCNA2,PLPPR4,KCNC1,KCNJ10,KCNJ11,KCNQ2" Mouse Phenotype MP:0001399 hyperactivity 1.13E-08 5.95E-05 1.75E-06 1.60E-05 63 488 "MAP6,MAPT,ADCYAP1R1,FABP7,AGT,PLA2G6,LRRC7,FGF14,ACTL6B,UNC79,ELMOD1,FOXG1,SGIP1,SLC1A2,SHANK2,SNAP25,ATP1A3,DKK3,GABBR1,SOX1,B3GALT2,TNIK,KIF1B,CPLX2,ADGRB2,NPAS3,NCDN,NEUROD1,GNAS,ADGRL3,DDR1,ZEB1,CAMK2A,TMEM151B,GRIA1,GRIA2,GRIA4,GRIN1,CCKBR,USP2,MFSD2A,PCDH9,PRMT8,ACOT7,CHRM1,CHRM4,CHRNB2,NLGN3,FTO,PPP3CB,FEZ1,ANKS1B,TUBB2B,KCNC1,KCNH1,SRGAP3,PCDH15,OLIG1,L1CAM,USH1C,EN2,RPE65,RCAN2" Mouse Phenotype MP:0011270 decreased excitatory postsynaptic current amplitude 1.19E-08 6.26E-05 1.79E-06 1.64E-05 13 31 "SH3GL2,NLGN1,CADPS,TMEM108,CACNA1A,GRIN1,SEZ6L,NLGN3,NRXN1,NRXN2,PACSIN1,DLG3,SEZ6" Mouse Phenotype MP:0000813 abnormal hippocampus layer morphology 1.52E-08 7.99E-05 2.22E-06 2.03E-05 25 113 "MAPT,APC2,AGT,FGF14,FOXG1,SLC1A2,CADPS,TMEM108,ATP1A3,FYN,NCAM1,NEUROD1,DCLK2,CDK5R2,CAMK2A,CD81,TNR,DCLK1,CRMP1,CTNND1,PROX1,LRP8,KIF2A,EFNA3,ABI2" Mouse Phenotype MP:0002885 abnormal AMPA-mediated synaptic currents 1.58E-08 8.34E-05 2.23E-06 2.04E-05 14 37 "GPR158,CNIH2,GRIA1,GRIA2,GRIA4,GRIN1,SHISA7,LGI1,NLGN3,NRXN1,NRXN2,CNIH3,SLC17A6,CACNG7" Mouse Phenotype MP:0002065 abnormal fear/anxiety-related behavior 1.61E-08 8.48E-05 2.23E-06 2.04E-05 54 393 "MAP6,MAPT,ATAT1,SLITRK1,ADCYAP1R1,FABP7,ADORA1,GPR158,KIAA1109,LRRC7,FGF14,APBA2,SHANK2,SNAP25,ATP1A2,ATP1A3,FYN,GABBR1,B3GALT2,GAD2,CPLX2,NPAS3,ADGRL3,ATF7,CACNA1E,DDR1,GPR19,GPR26,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,SHISA7,CCKBR,HRH3,PDE4B,PDYN,CHRNB2,NLGN3,DLGAP3,NRXN2,PRKCG,PRKCZ,PTCH1,SRGAP3,KCNJ11,PAK5,L1CAM,EFNA3,FGFBP3,SLC4A10" Mouse Phenotype MP:0002572 abnormal emotion/affect behavior 1.86E-08 9.81E-05 2.52E-06 2.30E-05 77 657 "MAG,MAP6,MAPT,ATAT1,SLITRK1,ADCYAP1R1,FABP7,ADORA1,GPR158,KIAA1109,PLA2G6,LRRC7,FGF14,ELMOD1,APBA2,CCDC88A,SHANK2,SNAP25,ATP1A2,ATP1A3,FYN,GABBR1,SOX1,B3GALT2,GAD2,JPH4,CPLX2,ADGRB2,NPAS3,KIRREL3,GNAS,ADGRL3,WSCD1,ATF7,CACNA1E,DDR1,ZEB1,GPR19,GPR26,HAP1,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,ATP13A2,SHISA7,CCKBR,P2RX7,HRH3,PRMT8,PDE4B,PDYN,CHRNB2,NLGN3,DLGAP3,NRXN2,PRKCG,PRKCZ,SIRPA,PTCH1,KCNC1,KCNH1,SRGAP3,KCNJ11,NAV2,OLIG1,SLC17A6,PAK5,L1CAM,RGS7,EFNA3,FGFBP3,SLC4A10,EN2" Mouse Phenotype MP:0002272 abnormal nervous system electrophysiology 2.08E-08 1.10E-04 2.74E-06 2.51E-05 50 353 "MBP,ADORA1,SCN4B,FGF14,SEMA6A,ANK3,SLC1A2,SLC1A6,MADD,SLC6A9,ATP1A2,ATP1A3,ATP2B2,GABBR1,SOX10,GAD2,JPH4,NKX6-2,NFASC,ERBIN,GJB1,NEUROD1,GNG3,CACNA1A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,TNR,LGI1,ASIC3,CHRM1,CHRM4,CHRNB2,PMP2,PACSIN1,KCNT2,KCNA1,KCNA2,KCNJ10,KCNJ11,PCDH15,KCNMA1,KCNN3,KCNQ2,DPP6,RGS7,ELAVL3" Mouse Phenotype MP:0001961 abnormal reflex 2.70E-08 1.42E-04 3.47E-06 3.17E-05 87 784 "MAG,EPS8,ACER3,MAPT,ACHE,MBP,ADGRV1,SLITRK1,RYR1,KIAA1109,LRRC7,FGF14,ELMOD1,MOG,SGIP1,PKP4,MADD,SLC6A9,SLC8A3,SHANK2,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,GABBR1,SOX1,B3GALT2,SOX10,JPH4,B4GALNT1,SALL3,KIF1B,CPLX2,NPAS3,NDUFA5,SMOC1,ERBIN,NELL1,AJAP1,VAMP1,NHLH1,GNAS,ROBO3,CDK5R2,CACNA1A,ATF7,ZEB1,NRDC,BRSK2,GRIA2,GRIA4,GRIK4,GRIN1,ATP13A2,CCKBR,USP2,PAX6,PCSK2,PRMT8,PDYN,NTSR2,ASIC3,CHRNB2,NLGN3,CPT1C,PMP2,ATCAY,POU3F4,ARHGEF4,DPYSL5,KCNA1,KCNA2,KCNJ10,PCDH15,KCNMA1,NAV2,DLG2,SLC17A6,ATN1,L1CAM,USH1C,EFNA3,ELAVL4,EN2,OLIG2,RPE65" Mouse Phenotype MP:0011267 abnormal excitatory postsynaptic current amplitude 3.49E-08 1.84E-04 4.37E-06 4.00E-05 14 39 "SH3GL2,NLGN1,CADPS,TMEM108,GAD2,CACNA1A,GRIN1,SEZ6L,NLGN3,NRXN1,NRXN2,PACSIN1,DLG3,SEZ6" Mouse Phenotype MP:0000950 abnormal seizure response to pharmacological agent 6.40E-08 3.37E-04 7.83E-06 7.16E-05 27 138 "MAPT,MBP,FGF14,AMPH,SLITRK3,SLC1A2,ATP1A3,GAD2,GFAP,CNTN2,CACNA1A,GRIA4,GRIK2,GRIK4,GRIN1,AIFM1,LGI1,PDYN,SERPINE2,MAPK10,KCNA1,KCNA2,PTPRO,KCNK2,KCNQ2,SLC4A10,SEZ6" Mouse Phenotype MP:0001473 reduced long term potentiation 6.77E-08 3.57E-04 8.10E-06 7.41E-05 29 156 "MAPT,ADCYAP1R1,FGF14,CNIH2,CCDC88A,SHANK2,B3GAT1,FYN,GABBR1,JPH4,CPLX2,NCAM1,NCDN,WWC1,CAMK2A,GRIA1,GRIK2,GRIK3,GRIK4,GRIN1,SHISA7,SERPINE2,PRKACB,PRKCG,SIRPA,CNIH3,LRP8,RASGRF1,EFNA3" Mouse Phenotype MP:0001469 abnormal contextual conditioning behavior 1.82E-07 9.60E-04 2.13E-05 1.95E-04 29 163 "MAPT,ADCYAP1R1,FABP7,FGF14,AMPH,ITSN1,SLC8A2,CCDC88A,TMEM108,ATP1A3,GAD2,SYT4,WWC1,CAMK2A,GRIA2,GRIK2,GRIN1,SHISA7,NLGN3,FEZ1,PRKCG,CTNND2,SPIRE1,LRP8,PTPRZ1,SLC17A6,RASGRF1,EFNA3,ABI2" Mouse Phenotype MP:0001898 abnormal long term depression 2.20E-07 1.16E-03 2.52E-05 2.31E-04 21 95 "SCN4B,LRRC7,SLC8A2,SHANK2,CSPG5,SORCS3,NCAM1,GFAP,NCDN,WWC1,CAMK2A,GRIA1,GRIA2,GRIN1,CHRM1,NLGN3,PRKACB,CALY,DPYSL5,ANKS1B,SLC17A6" Mouse Phenotype MP:0001468 abnormal temporal memory 2.30E-07 1.21E-03 2.57E-05 2.35E-04 32 193 "MAPT,ADCYAP1R1,FABP7,FGF14,AMPH,ITSN1,SLC8A2,CCDC88A,TMEM108,ATP1A3,GAD2,JPH4,SYT4,WWC1,CAMK2A,GRIA2,GRIK2,GRIN1,SHISA7,PCDH9,NLGN3,FEZ1,PRKCG,CTNND2,SPIRE1,LRP8,PTPRZ1,SRGAP3,SLC17A6,RASGRF1,EFNA3,ABI2" Mouse Phenotype MP:0001362 abnormal anxiety-related response 3.72E-07 1.96E-03 4.08E-05 3.73E-04 47 353 "MAP6,MAPT,ATAT1,SLITRK1,ADCYAP1R1,FABP7,ADORA1,GPR158,KIAA1109,LRRC7,FGF14,APBA2,SHANK2,SNAP25,ATP1A2,ATP1A3,B3GALT2,GAD2,CPLX2,NPAS3,ADGRL3,ATF7,CACNA1E,DDR1,GPR19,GPR26,CAMK2A,GRIA1,GRIA2,GRIA4,GRIN1,GRM3,CCKBR,HRH3,PDE4B,PDYN,CHRNB2,NLGN3,DLGAP3,NRXN2,PRKCG,PRKCZ,KCNJ11,L1CAM,EFNA3,FGFBP3,SLC4A10" Mouse Phenotype MP:0000847 abnormal metencephalon morphology 5.07E-07 2.67E-03 5.45E-05 4.98E-04 60 505 "ACER3,APC2,MBP,CEND1,WLS,MDM4,SEMA6A,ANK1,ANK3,SHANK2,CADPS,ASCL1,ASTN1,ATM,ATP2B2,TNIK,NMNAT2,B4GALNT1,NKX6-2,DNER,NPAS3,NFASC,NCAM1,BCL2L2,FGF17,NEUROD1,NFIA,MLC1,GNAS,ROBO3,CAMTA1,CDK5R2,CACNA1A,AIFM1,PAX6,DCLK1,RBFOX2,LGI1,PRMT8,PDYN,GPR37L1,ADGRG1,SERPINE2,CNTN1,CP,POU3F2,DPYSL5,TUBB2B,PTCH1,LRP8,KIF2A,OLIG1,DSCAM,L1CAM,RET,EEF1A2,VANGL2,EN2,EPB41L1,EPB41L2" Mouse Phenotype MP:0004753 abnormal miniature excitatory postsynaptic currents 5.56E-07 2.93E-03 5.74E-05 5.25E-04 23 117 "MAPT,LRRTM4,CNIH2,SH3GL2,MADD,SHANK2,CADPS,TMEM108,SNAP25,TNIK,CPLX2,CACNA1A,GRIA1,GRIN1,SHISA7,CDH8,LGI1,CHRM1,NLGN3,NRXN1,PACSIN1,CNIH3,PLPPR4" Mouse Phenotype MP:0000812 abnormal dentate gyrus morphology 5.56E-07 2.93E-03 5.74E-05 5.25E-04 23 117 "MAPT,APC2,ATAT1,FABP7,LRRTM4,FGF14,FOXG1,APBB1,CCDC88A,CADPS,ATP1A3,FYN,SOX1,GFAP,NCDN,NEUROD1,DCLK2,CDK5R2,CAMK2A,DCLK1,PROX1,LRP8,ABI2" Mouse Phenotype MP:0011003 reduced AMPA-mediated synaptic currents 1.09E-06 5.76E-03 1.11E-04 1.01E-03 9 20 "CNIH2,GRIA1,GRIN1,SHISA7,NLGN3,NRXN1,NRXN2,CNIH3,CACNG7" Mouse Phenotype MP:0002888 abnormal NMDA-mediated synaptic currents 1.20E-06 6.34E-03 1.20E-04 1.09E-03 11 31 "EPS8,FABP7,CLSTN1,SLC6A9,GRIK4,GRIN1,LGI1,DLGAP3,SERPINE2,NRXN1,NRXN2" Mouse Phenotype MP:0001968 abnormal touch/ nociception 1.27E-06 6.71E-03 1.24E-04 1.14E-03 41 302 "RYR1,ADORA1,ADORA3,ELMOD1,SEMA6C,MADD,SLC6A9,SNAP25,ATP1A2,ATP1A3,GABBR1,SOX10,KIF1B,ERBIN,CDK5R2,CACNA1A,PRLHR,BRSK2,GRIA1,GRIA2,GRIA4,CCKBR,P2RX7,CDH8,PCSK2,PIRT,PDYN,NTSR2,ADGRG1,ASIC3,CHRNB2,KCNT2,PRKCG,ARHGEF4,KCNA1,KCNA6,PTPRZ1,NAV2,DLG2,SLC17A6,L1CAM" Mouse Phenotype MP:0008917 abnormal oligodendrocyte physiology 1.57E-06 8.29E-03 1.51E-04 1.38E-03 10 26 "MOG,SOX10,NFASC,GFAP,GJB1,MLC1,GPM6B,TNFRSF1B,HEPACAM,TENM4" Mouse Phenotype MP:0001363 increased anxiety-related response 1.97E-06 1.04E-02 1.85E-04 1.69E-03 32 212 "MAP6,MAPT,ATAT1,SLITRK1,FABP7,ADORA1,LRRC7,FGF14,APBA2,SHANK2,SNAP25,ATP1A2,ATP1A3,GAD2,CPLX2,ATF7,CACNA1E,GPR19,GPR26,GRIA1,GRIA2,GRIA4,GRIN1,CCKBR,HRH3,NLGN3,DLGAP3,NRXN2,KCNJ11,L1CAM,EFNA3,FGFBP3" Mouse Phenotype MP:0003088 abnormal prepulse inhibition 2.48E-06 1.31E-02 2.29E-04 2.10E-03 30 194 "MAG,MAP6,ADGRV1,FABP7,LRRC7,ELMOD1,CCDC88A,TMEM108,SNAP25,ATP1A3,ATP2B2,GABBR1,GAD2,STARD10,NPAS3,NCDN,ATF7,GRIA4,GRIN1,PTPN5,IGSF21,PCDH9,NTSR2,ACOT7,NRXN1,ANKS1B,SRGAP3,KCNQ2,OLIG1,EFNA3" Mouse Phenotype MP:0000920 abnormal myelination 2.74E-06 1.44E-02 2.49E-04 2.27E-03 31 205 "MAG,MBP,ACTL6B,MOBP,FOXG1,MOG,ZNF365,FYN,GABBR1,CADM3,SOX10,NKX6-2,ERBIN,GFAP,GJB1,MYRF,GPM6B,GPR17,NRDC,TNFRSF1B,CP,POU3F2,TENM4,ITGAV,PTPRE,PTPRZ1,KCNJ10,PEX5,OLIG1,EEF1A2,OLIG2" Mouse Phenotype MP:0003997 tonic-clonic seizures 3.20E-06 1.69E-02 2.86E-04 2.61E-03 17 77 "ST8SIA1,GABBR1,GAD2,B4GALNT1,NEUROD1,DCLK2,GNG3,GRIA2,GRIK4,GRIN1,LGI1,PACSIN1,KCNA1,PLPPR4,KCNJ10,KCNJ11,KCNQ2" Mouse Phenotype MP:0000841 abnormal hindbrain morphology 3.37E-06 1.77E-02 2.90E-04 2.66E-03 63 571 "ACER3,MAPT,APC2,MBP,CEND1,WLS,MDM4,SEMA6A,BBOX1,ANK1,ANK3,SHANK2,CADPS,ASCL1,ASTN1,ATM,ATP2B2,TNIK,NMNAT2,B4GALNT1,NKX6-2,DNER,NPAS3,NFASC,NCAM1,BCL2L2,FGF17,NEUROD1,NFIA,MLC1,GNAS,ROBO3,CAMTA1,CDK5R2,CACNA1A,AIFM1,PAX6,DCLK1,RBFOX2,LGI1,PRMT8,PDYN,GPR37L1,ADGRG1,SERPINE2,CNTN1,CP,POU3F2,DPYSL5,TUBB2B,PTCH1,LRP8,KIF2A,OLIG1,DSCAM,L1CAM,RET,RFX4,EEF1A2,VANGL2,EN2,EPB41L1,EPB41L2" Mouse Phenotype MP:0001393 ataxia 3.42E-06 1.80E-02 2.90E-04 2.66E-03 43 336 "MAPT,MBP,F3,PLA2G6,FGF14,ANK3,APBA2,SNAP25,ATM,ATP1A3,ATP2B2,B4GALNT1,NFASC,BCL2L2,GJB1,NEUROD1,MLC1,GNAS,ROBO3,CAMTA1,MYRF,CACNA1A,GPM6B,GRIA4,GRIN1,MFSD2A,AIFM1,RBFOX2,CNTN1,ATCAY,PTCH1,ITGAV,LRP8,BLOC1S6,KCNA1,KCNA2,KCNC1,KCNJ10,PCDH15,KCNMA1,PEX5,CACNG7,OLIG2" Mouse Phenotype MP:0000952 abnormal CNS glial cell morphology 3.42E-06 1.80E-02 2.90E-04 2.66E-03 43 336 "MAG,MAPT,MBP,NDRG2,FGF14,FOXG1,MOG,ZNF365,ASCL1,ATP1A3,SOX10,DNER,NCAM1,GFAP,NCDN,GJB1,NEUROD1,MLC1,GLS,NKX2-2,MYRF,GPM6B,GPR17,GRIA2,ATP13A2,CRB1,CD81,TNFRSF1B,ADGRG1,SERPINE2,CADM1,CP,POU3F2,TENM4,HES5,KLK6,KCNA1,PTPRZ1,KCNJ10,PEX5,OLIG1,VANGL2,OLIG2" Mouse Phenotype MP:0012079 abnormal spinal reflex 3.71E-06 1.96E-02 3.05E-04 2.79E-03 20 103 "RYR1,ELMOD1,MADD,SLC6A9,SNAP25,ATP1A2,GABBR1,SOX10,KIF1B,ERBIN,CDK5R2,CACNA1A,BRSK2,CCKBR,PCSK2,PDYN,ASIC3,ARHGEF4,DLG2,L1CAM" Mouse Phenotype MP:0005316 abnormal response to tactile stimuli 3.71E-06 1.96E-02 3.05E-04 2.79E-03 20 103 "RYR1,ELMOD1,MADD,SLC6A9,SNAP25,ATP1A2,GABBR1,SOX10,KIF1B,ERBIN,CDK5R2,CACNA1A,BRSK2,CCKBR,PCSK2,PDYN,ASIC3,ARHGEF4,DLG2,L1CAM" Mouse Phenotype MP:0003312 abnormal locomotor coordination 3.81E-06 2.01E-02 3.05E-04 2.79E-03 72 685 "MAG,MAPT,ACHE,APC2,MBP,CEND1,F3,PLA2G6,FGF14,ELMOD1,ANK3,APBA2,MSRA,SNAP25,ATM,ATP1A3,ATP2B2,GABBR1,SOX10,B4GALNT1,CPLX2,NPAS3,NFASC,BCL2L2,SMOC1,FGF17,GJB1,NEUROD1,MLC1,VAMP1,GNAS,DDHD2,ROBO3,CAMTA1,MYRF,CACNA1A,GPM6B,GRIA4,GRIN1,ATP13A2,MFSD2A,AIFM1,NEURL1,PAH,RBFOX2,SEZ6L,PRMT8,NTSR2,CNTN1,ATCAY,CP,POU3F4,PTCH1,ITGAV,PTHLH,LRP8,BLOC1S6,KCNA1,KCNA2,KCNC1,KCNJ10,PCDH15,KCNMA1,PEX5,ATN1,DSCAM,L1CAM,USH1C,ATL1,CACNG7,OLIG2,SEZ6" Mouse Phenotype MP:0012349 increased susceptibility to induction of seizure by inducing agent 3.83E-06 2.02E-02 3.05E-04 2.79E-03 21 112 "MBP,FGF14,AMPH,SLITRK3,SLC1A2,ATP1A3,GFAP,CNTN2,CACNA1A,GRIK2,GRIK4,GRIN1,LGI1,PDYN,CHRNB2,SERPINE2,KCNA1,KCNA2,PTPRO,KCNK2,KCNQ2" Mouse Phenotype MP:0002945 abnormal inhibitory postsynaptic currents 4.43E-06 2.33E-02 3.48E-04 3.19E-03 18 87 "SEMA6A,APBA2,NLGN1,SLC6A9,CSPG5,GABBR1,GAD2,CPLX2,DCLK2,CACNA1A,GRIK2,CHRM1,NLGN3,NRXN2,PACSIN1,KCNA1,KCNA2,SV2A" Mouse Phenotype MP:0001496 audiogenic seizures 4.50E-06 2.37E-02 3.48E-04 3.19E-03 9 23 "MBP,ADGRV1,ST8SIA1,FYN,GABBR1,B4GALNT1,GNG3,PAH,LGI1" Mouse Phenotype MP:0009142 decreased prepulse inhibition 5.32E-06 2.80E-02 4.06E-04 3.71E-03 24 142 "MAG,MAP6,ADGRV1,FABP7,LRRC7,ELMOD1,CCDC88A,TMEM108,SNAP25,ATP1A3,GAD2,STARD10,NCDN,ATF7,GRIA4,GRIN1,IGSF21,PCDH9,ACOT7,NRXN1,ANKS1B,SRGAP3,KCNQ2,OLIG1" Mouse Phenotype MP:0000849 abnormal cerebellum morphology 5.41E-06 2.85E-02 4.07E-04 3.72E-03 54 470 "ACER3,APC2,MBP,CEND1,WLS,MDM4,SEMA6A,ANK1,ANK3,SHANK2,CADPS,ASTN1,ATM,ATP2B2,TNIK,B4GALNT1,DNER,NPAS3,NFASC,NCAM1,BCL2L2,FGF17,NEUROD1,NFIA,MLC1,GNAS,CAMTA1,CDK5R2,CACNA1A,AIFM1,PAX6,DCLK1,RBFOX2,LGI1,PRMT8,PDYN,GPR37L1,ADGRG1,SERPINE2,CNTN1,CP,POU3F2,DPYSL5,TUBB2B,PTCH1,LRP8,KIF2A,OLIG1,DSCAM,L1CAM,EEF1A2,EN2,EPB41L1,EPB41L2" Mouse Phenotype MP:0002578 impaired ability to fire action potentials 6.81E-06 3.58E-02 5.05E-04 4.62E-03 9 24 "ANK3,MADD,GAD2,NFASC,NEUROD1,GRIA1,GRIA4,KCNA2,KCNMA1" Mouse Phenotype MP:0009939 abnormal hippocampus neuron morphology 7.62E-06 4.01E-02 5.57E-04 5.10E-03 22 126 "MAPT,APC2,FGF14,FOXG1,ANK3,SLC1A2,CADPS,TMEM108,ATP1A3,FYN,GFAP,NEUROD1,DCLK2,CAMK2A,GRIA2,CD81,HPCA,CRMP1,CTNND1,PROX1,EFNA3,ABI2" Mouse Phenotype MP:0004097 abnormal cerebellar cortex morphology 7.90E-06 4.16E-02 5.70E-04 5.21E-03 45 370 "ACER3,APC2,CEND1,MDM4,SEMA6A,ANK1,ANK3,SHANK2,CADPS,ASTN1,ATM,ATP2B2,TNIK,B4GALNT1,DNER,NPAS3,NFASC,BCL2L2,FGF17,NEUROD1,NFIA,GNAS,CAMTA1,CDK5R2,CACNA1A,AIFM1,PAX6,DCLK1,RBFOX2,LGI1,PRMT8,PDYN,GPR37L1,ADGRG1,SERPINE2,CNTN1,CP,POU3F2,DPYSL5,PTCH1,LRP8,DSCAM,L1CAM,EEF1A2,EN2" Mouse Phenotype MP:0005402 abnormal action potential 8.25E-06 4.35E-02 5.87E-04 5.37E-03 23 136 "MBP,SCN4B,ANK3,MADD,ATP1A2,ATP1A3,ATP2B2,GABBR1,SOX10,GAD2,NFASC,NEUROD1,CACNA1A,GRIA1,GRIA4,KCNT2,KCNA1,KCNA2,KCNJ11,PCDH15,KCNMA1,KCNN3,KCNQ2" Mouse Phenotype MP:0003634 abnormal glial cell morphology 8.78E-06 4.62E-02 6.16E-04 5.64E-03 50 430 "MAG,MAPT,MBP,NDRG2,FGF14,FOXG1,MOG,ZNF365,ASCL1,ATP1A3,SOX10,DNER,NCAM1,GFAP,NCDN,GJB1,NEUROD1,NFIA,MLC1,GLS,NKX2-2,MYRF,GPM6B,GPR17,GRIA2,ATP13A2,CRB1,CD81,TNFRSF1B,LGI1,ACOT7,ADGRG1,SERPINE2,CADM1,CNTN1,CP,POU3F2,TENM4,HES5,KLK6,ITGAV,KCNA1,PTPRZ1,KCNJ10,PEX5,OLIG1,L1CAM,EEF1A2,VANGL2,OLIG2" Mouse Phenotype MP:0002906 increased susceptibility to pharmacologically induced seizures 1.05E-05 5.55E-02 7.30E-04 6.68E-03 20 110 "MBP,FGF14,AMPH,SLITRK3,SLC1A2,ATP1A3,GFAP,CNTN2,CACNA1A,GRIK2,GRIK4,GRIN1,LGI1,PDYN,SERPINE2,KCNA1,KCNA2,PTPRO,KCNK2,KCNQ2" Mouse Phenotype MP:0008143 abnormal dendrite morphology 1.21E-05 6.35E-02 8.25E-04 7.54E-03 31 220 "MAPT,CEND1,GPR158,LRRC7,SEMA6A,ACTL6B,CLSTN1,CCDC88A,SHANK2,TMEM108,ATM,KIF21B,BCL2L2,CACNA1A,CAMK2A,GRIA1,GRIK4,PCDH9,PRMT8,PDE4B,JAM2,SEMA5B,CPT1C,CNTN1,CRMP1,DPYSL5,SPIRE1,SRGAP3,SLC17A6,OLIG2,SEZ6" Mouse Phenotype MP:0009748 abnormal behavioral response to addictive substance 1.63E-05 8.56E-02 1.10E-03 1.00E-02 19 104 "MAP6,SCN4B,UNC79,AQP4,SLC6A9,ATP1A3,FYN,GLS,ADGRL3,PRLHR,GRIA1,GRIN1,CCKBR,CD81,CHRM4,CHRNB2,PRKCG,KCNC1,SLC17A6" Mouse Phenotype MP:0008284 abnormal hippocampus pyramidal cell layer 1.81E-05 9.54E-02 1.21E-03 1.11E-02 17 87 "MAPT,APC2,FGF14,FOXG1,SLC1A2,CADPS,ATP1A3,FYN,NCAM1,DCLK2,CD81,TNR,CRMP1,CTNND1,LRP8,EFNA3,ABI2" Mouse Phenotype MP:0008285 abnormal hippocampus granule cell layer 2.06E-05 1.09E-01 1.36E-03 1.24E-02 9 27 "APC2,AGT,FOXG1,TMEM108,ATP1A3,NEUROD1,DCLK2,CAMK2A,PROX1" Mouse Phenotype MP:0009538 abnormal synapse morphology 2.34E-05 1.23E-01 1.52E-03 1.39E-02 29 206 "MAP6,MAPT,SH3GL2,GAS7,SLITRK3,NLGN1,MADD,SHANK2,CADPS,KIF21B,NKX6-2,LHFPL4,KIF1B,NFASC,CACNA1A,CAMK2A,GRIK4,IGSF21,TNR,NLGN3,PACSIN1,SIRPA,DNAJC6,DLG3,SLC17A6,DTNA,RET,EEF1A2,OLIG2" Mouse Phenotype MP:0009358 environmentally induced seizures 2.40E-05 1.26E-01 1.54E-03 1.41E-02 12 48 "MBP,ADGRV1,ADORA1,ST8SIA1,ATP1A3,FYN,GABBR1,B4GALNT1,GNG3,CACNA1A,PAH,LGI1" Mouse Phenotype MP:0002918 abnormal paired-pulse facilitation 2.53E-05 1.34E-01 1.61E-03 1.47E-02 15 72 "MAPT,APBA2,SLC8A2,CSPG5,SNAP25,TNIK,CACNA1A,CAMK2A,GRIA2,GRIK2,GRIK3,GRIK4,CHRM1,SIRPA,KCNA1" Domain SM00408 IGc2 SMART 2.05E-07 6.99E-04 2.34E-04 2.04E-03 31 235 "MAG,DSCAML1,FCGR1A,FCGR1B,LRRC4C,IGSF9B,PALLD,MYBPC1,CADM3,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,LILRA1,OPCML,LILRA4,IGFN1,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,IGSF1,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain IPR003598 Ig_sub2 InterPro 2.05E-07 6.99E-04 2.34E-04 2.04E-03 31 235 "MAG,DSCAML1,FCGR1A,FCGR1B,LRRC4C,IGSF9B,PALLD,MYBPC1,CADM3,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,LILRA1,OPCML,LILRA4,IGFN1,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,IGSF1,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain SM00079 PBPe SMART 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain SM00918 Lig_chan-Glu_bd SMART 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain IPR001320 Iontro_rcpt InterPro 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain IPR001508 Iono_rcpt_met InterPro 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain PF00060 Lig_chan Pfam 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain PF10613 Lig_chan-Glu_bd Pfam 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain IPR019594 Glu/Gly-bd InterPro 6.60E-07 2.25E-03 2.34E-04 2.04E-03 8 18 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1" Domain PS50026 EGF_3 PROSITE 7.17E-07 2.45E-03 2.34E-04 2.04E-03 30 236 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,ASTN2,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,MASP1,LRP8,CRTAC1" Domain IPR013783 Ig-like_fold InterPro 7.93E-07 2.71E-03 2.34E-04 2.04E-03 63 707 "MAG,F3,DSCAML1,FCGR1A,FCGR1B,SCN4B,MOG,TRIM46,BCAN,LRRC4C,SHANK2,ASTN1,IGSF9B,PHYHIPL,PALLD,SCN3B,MYBPC1,CADM3,ILDR2,NFASC,NCAM1,KIRREL3,ASTN2,SEMA4A,ROBO3,CAMTA1,UNC5D,CNTN2,LRIT2,LILRA1,VSTM2A,OPCML,TMEM25,TIE1,IGSF21,TNR,LILRA4,IGFN1,FNDC5,HAPLN2,JAM2,HEPACAM,CADM1,NOMO2,NEGR1,FLRT1,PLXNB3,CNTN1,CSF3R,VCAN,NCAN,RBPJ,PRKAB2,IGSF1,PHYHIP,SIRPA,CADM2,PTPRD,PTPRO,PTPRZ1,NTM,DSCAM,L1CAM" Domain 2.60.40.10 - Gene3D 8.80E-07 3.00E-03 2.34E-04 2.04E-03 60 663 "MAG,F3,DSCAML1,FCGR1A,FCGR1B,SCN4B,MOG,TRIM46,BCAN,LRRC4C,ASTN1,IGSF9B,PHYHIPL,PALLD,SCN3B,MYBPC1,CADM3,ILDR2,NFASC,NCAM1,KIRREL3,ASTN2,ROBO3,CAMTA1,UNC5D,CNTN2,LRIT2,LILRA1,VSTM2A,OPCML,TMEM25,TIE1,IGSF21,TNR,LILRA4,IGFN1,FNDC5,HAPLN2,JAM2,HEPACAM,CADM1,NOMO2,NEGR1,FLRT1,PLXNB3,CNTN1,CSF3R,VCAN,NCAN,RBPJ,IGSF1,PHYHIP,SIRPA,CADM2,PTPRD,PTPRO,PTPRZ1,NTM,DSCAM,L1CAM" Domain PF07679 I-set Pfam 9.59E-07 3.27E-03 2.34E-04 2.04E-03 26 190 "MAG,DSCAML1,LRRC4C,IGSF9B,PALLD,MYBPC1,CADM3,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,OPCML,IGFN1,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain IPR013098 Ig_I-set InterPro 9.59E-07 3.27E-03 2.34E-04 2.04E-03 26 190 "MAG,DSCAML1,LRRC4C,IGSF9B,PALLD,MYBPC1,CADM3,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,OPCML,IGFN1,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain IPR009071 HMG_box_dom InterPro 1.50E-06 5.10E-03 3.04E-04 2.65E-03 14 65 "SOX6,SH3GL2,SMARCE1,SOX1,SOX5,SOX10,TCF7L2,MAEL,HMGB1,UBTF,NSD2,CHD5,PROX1,TOX" Domain SM00409 IG SMART 1.52E-06 5.17E-03 3.04E-04 2.65E-03 43 421 "MAG,DSCAML1,FCGR1A,FCGR1B,SCN4B,MOG,BCAN,LRRC4C,IGSF9B,PALLD,SCN3B,MYBPC1,CADM3,ILDR2,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,LILRA1,VSTM2A,OPCML,TIE1,IGSF21,LILRA4,IGFN1,HAPLN2,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,VCAN,NCAN,IGSF1,SIRPA,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain IPR003599 Ig_sub InterPro 1.52E-06 5.17E-03 3.04E-04 2.65E-03 43 421 "MAG,DSCAML1,FCGR1A,FCGR1B,SCN4B,MOG,BCAN,LRRC4C,IGSF9B,PALLD,SCN3B,MYBPC1,CADM3,ILDR2,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,LILRA1,VSTM2A,OPCML,TIE1,IGSF21,LILRA4,IGFN1,HAPLN2,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,VCAN,NCAN,IGSF1,SIRPA,CADM2,PTPRD,NTM,DSCAM,L1CAM" Domain SM00060 FN3 SMART 1.95E-06 6.65E-03 3.70E-04 3.22E-03 25 185 "DSCAML1,TRIM46,ASTN1,IGSF9B,PHYHIPL,MYBPC1,NFASC,NCAM1,ASTN2,ROBO3,CNTN2,LRIT2,TIE1,TNR,IGFN1,FNDC5,FLRT1,CNTN1,CSF3R,PHYHIP,PTPRD,PTPRO,PTPRZ1,DSCAM,L1CAM" Domain SM00181 EGF SMART 2.19E-06 7.48E-03 3.94E-04 3.43E-03 29 236 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,BRINP2,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,BRINP3,LRP8" Domain PS00022 EGF_1 PROSITE 3.93E-06 1.34E-02 6.70E-04 5.84E-03 30 256 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,ASTN2,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,MASP1,LRP8,CRTAC1" Domain IPR001828 ANF_lig-bd_rcpt InterPro 5.44E-06 1.86E-02 8.43E-04 7.35E-03 10 37 "GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" Domain PF01094 ANF_receptor Pfam 5.44E-06 1.86E-02 8.43E-04 7.35E-03 10 37 "GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" Domain IPR003961 FN3_dom InterPro 5.80E-06 1.98E-02 8.60E-04 7.49E-03 26 209 "F3,DSCAML1,TRIM46,ASTN1,IGSF9B,PHYHIPL,MYBPC1,NFASC,NCAM1,ASTN2,ROBO3,CNTN2,LRIT2,TIE1,TNR,IGFN1,FNDC5,FLRT1,CNTN1,CSF3R,PHYHIP,PTPRD,PTPRO,PTPRZ1,DSCAM,L1CAM" Domain IPR000742 EGF-like_dom InterPro 6.92E-06 2.36E-02 9.26E-04 8.07E-03 29 250 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,MASP1,LRP8,CRTAC1" Domain 1.10.30.10 - Gene3D 7.25E-06 2.47E-02 9.26E-04 8.07E-03 12 55 "SOX6,SMARCE1,SOX1,SOX5,SOX10,TCF7L2,MAEL,HMGB1,UBTF,NSD2,CHD5,TOX" Domain PF00041 fn3 Pfam 7.32E-06 2.50E-02 9.26E-04 8.07E-03 22 162 "DSCAML1,TRIM46,IGSF9B,PHYHIPL,MYBPC1,NFASC,NCAM1,ROBO3,CNTN2,TIE1,TNR,IGFN1,FNDC5,FLRT1,CNTN1,CSF3R,PHYHIP,PTPRD,PTPRO,PTPRZ1,DSCAM,L1CAM" Domain PS50853 FN3 PROSITE 7.33E-06 2.50E-02 9.26E-04 8.07E-03 25 199 "DSCAML1,TRIM46,ASTN1,IGSF9B,PHYHIPL,MYBPC1,NFASC,NCAM1,ASTN2,ROBO3,CNTN2,LRIT2,TIE1,TNR,IGFN1,FNDC5,FLRT1,CNTN1,CSF3R,PHYHIP,PTPRD,PTPRO,PTPRZ1,DSCAM,L1CAM" Domain 2.30.29.30 - Gene3D 8.12E-06 2.77E-02 9.89E-04 8.62E-03 39 391 "EPS8,FAM43B,RTKN,PLEKHG5,CDC42BPA,RASA3,ITSN1,APBA2,APBB1,DOCK10,DGKD,CADPS,KIF1B,PHLDB1,ARHGEF7,PSD3,TNS1,PLEKHB1,ARHGAP22,ANLN,VAV2,OSBPL3,PLCH2,ARHGEF4,NOS1AP,PSD,ANKS1B,ELMO1,RABGAP1L,PID1,DNM2,PLEKHB2,RASGRF1,ARHGEF10L,ARHGAP12,PLEKHO1,EPB41,EPB41L1,EPB41L2" Domain PS01186 EGF_2 PROSITE 8.49E-06 2.90E-02 9.99E-04 8.70E-03 30 266 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,ASTN2,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,MASP1,LRP8,CRTAC1" Domain PS50923 SUSHI PROSITE 8.84E-06 3.02E-02 1.00E-03 8.73E-03 12 56 "CSMD2,CSMD3,SELL,BCAN,GABBR1,SEZ6L,HPR,VCAN,NCAN,MASP1,SUSD4,SEZ6" Domain IPR028082 Peripla_BP_I InterPro 9.11E-06 3.11E-02 1.00E-03 8.73E-03 10 39 "GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" Domain IPR000436 Sushi_SCR_CCP_dom InterPro 1.07E-05 3.66E-02 1.14E-03 9.96E-03 12 57 "CSMD2,CSMD3,SELL,BCAN,GABBR1,SEZ6L,HPR,VCAN,NCAN,MASP1,SUSD4,SEZ6" Domain IPR008145 GK/Ca_channel_bsu InterPro 1.68E-05 5.74E-02 1.58E-03 1.37E-02 8 26 "MAGI3,CACNB2,TJP1,MAGI1,TJP2,MAGI2,DLG2,DLG3" Domain PF00625 Guanylate_kin Pfam 1.68E-05 5.74E-02 1.58E-03 1.37E-02 8 26 "MAGI3,CACNB2,TJP1,MAGI1,TJP2,MAGI2,DLG2,DLG3" Domain SM00072 GuKc SMART 1.68E-05 5.74E-02 1.58E-03 1.37E-02 8 26 "MAGI3,CACNB2,TJP1,MAGI1,TJP2,MAGI2,DLG2,DLG3" Domain IPR008144 Guanylate_kin-like_dom InterPro 1.68E-05 5.74E-02 1.58E-03 1.37E-02 8 26 "MAGI3,CACNB2,TJP1,MAGI1,TJP2,MAGI2,DLG2,DLG3" Domain IPR013032 EGF-like_CS InterPro 1.71E-05 5.83E-02 1.58E-03 1.37E-02 29 262 "CNTNAP3,SELL,NTNG1,BCAN,CSPG5,SLIT1,DLL3,ASTN1,NRG3,MEGF11,ADAM15,DNER,NELL1,VWCE,CRB1,TIE1,TLL2,TNR,TMEFF2,NRXN1,NRXN2,FAT3,TENM4,ATRNL1,VCAN,NCAN,MASP1,LRP8,CRTAC1" Pathway 1268763 Neuronal System BioSystems: REACTOME 5.29E-24 1.07E-20 1.07E-20 8.80E-20 67 351 "ABAT,ACHE,SYT9,RTN3,ACTN2,ADCY2,NLGN4X,LRRTM4,PPFIA1,APBA2,NLGN1,SLC1A2,SLC1A6,SLC1A7,SHANK2,SNAP25,GABBR1,GAD2,ABCC8,GLS,GNG3,GNG4,CACNA1A,CACNA1E,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,KCNK10,CHRNB2,NLGN3,DLGAP3,NRXN1,NRXN2,PRKACB,PRKCG,LRRTM3,KCNA1,KCNA2,KCNA4,PTPRD,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG2,DLG3,RASGRF1,ABCC9,EPB41,EPB41L1,EPB41L2" Pathway P00037 Ionotropic glutamate receptor pathway PantherDB 5.75E-13 1.17E-09 5.84E-10 4.79E-09 18 46 "SLC1A2,SLC1A6,SLC1A7,SNAP25,VAMP1,CACNA1A,CACNA1E,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,SLC17A6" Pathway 1427849 Protein-protein interactions at synapses BioSystems: REACTOME 6.93E-12 1.41E-08 4.70E-09 3.85E-08 21 73 "SYT9,RTN3,NLGN4X,LRRTM4,APBA2,NLGN1,SHANK2,GRIA1,GRIA4,GRIN1,NLGN3,DLGAP3,NRXN1,NRXN2,LRRTM3,PTPRD,DLG2,DLG3,EPB41,EPB41L1,EPB41L2" Pathway 1268766 Transmission across Chemical Synapses BioSystems: REACTOME 8.53E-11 1.73E-07 4.33E-08 3.55E-07 35 218 "ABAT,ACHE,ACTN2,ADCY2,PPFIA1,SLC1A2,SLC1A6,SLC1A7,SNAP25,GABBR1,GAD2,GLS,GNG3,GNG4,CACNA1A,CACNA1E,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,CHRNB2,PRKACB,PRKCG,KCNJ4,KCNJ9,KCNJ10,DLG3,RASGRF1,EPB41L1" Pathway 1339115 Cardiac conduction BioSystems: REACTOME 2.65E-10 5.38E-07 1.08E-07 8.81E-07 27 142 "KCNIP2,RYR1,SCN3A,SCN4B,FGF14,SLC8A2,SLC8A3,ASPH,SLN,ATP1A2,ATP1A3,ATP2B2,SCN3B,AHCYL1,FXYD6,NPPA,CACNB2,CAMK2A,CAMK2G,KCNK10,KCND3,KCNJ4,KCNJ11,KCNK1,KCNK2,ABCC9,CACNG7" Pathway 1268821 Potassium Channels BioSystems: REACTOME 6.74E-10 1.37E-06 2.01E-07 1.65E-06 22 100 "GABBR1,ABCC8,GNG3,GNG4,KCNK10,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9" Pathway 1427850 Interactions of neurexins and neuroligins at synapses BioSystems: REACTOME 6.92E-10 1.41E-06 2.01E-07 1.65E-06 17 59 "SYT9,NLGN4X,LRRTM4,APBA2,NLGN1,SHANK2,GRIN1,NLGN3,DLGAP3,NRXN1,NRXN2,LRRTM3,DLG2,DLG3,EPB41,EPB41L1,EPB41L2" Pathway 1269868 Muscle contraction BioSystems: REACTOME 1.02E-09 2.07E-06 2.59E-07 2.13E-06 32 204 "ACTN2,KCNIP2,RYR1,SCN3A,SCN4B,FGF14,SORBS1,SLC8A2,SLC8A3,ASPH,SLN,ATP1A2,ATP1A3,ATP2B2,SCN3B,MYBPC1,AHCYL1,FXYD6,NPPA,CACNB2,CAMK2A,CAMK2G,KCNK10,TPM3,TPM4,KCND3,KCNJ4,KCNJ11,KCNK1,KCNK2,ABCC9,CACNG7" Pathway P00039 Metabotropic glutamate receptor group III pathway PantherDB 2.77E-09 5.64E-06 6.26E-07 5.13E-06 17 64 "SLC1A2,SLC1A6,SLC1A7,SNAP25,VAMP1,GNG3,GNG4,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,PRKACB" Pathway 213818 Glutamatergic synapse BioSystems: KEGG 9.12E-09 1.85E-05 1.85E-06 1.52E-05 22 114 "ADCY2,SLC1A2,SLC1A6,SLC1A7,SHANK2,GLS,GNAS,GNG3,GNG4,CACNA1A,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PPP3CB,PRKACB,PRKCG,SLC17A6" Pathway 1270303 Axon guidance BioSystems: REACTOME 5.48E-08 1.11E-04 1.01E-05 8.30E-05 55 554 "ACTN2,SCN3A,SCN4B,FGF1,SEMA6A,ANK1,ANK2,ANK3,RASA3,ITSN1,SH3GL2,SHTN1,SLIT1,NRG3,FYN,SCN3B,NFASC,NCAM1,CLASP2,GFRA1,FGF17,RND1,ARHGEF7,SEMA4A,ROBO3,UNC5D,CNTN2,CACNB2,CAMK2A,CAMK2G,GRIN1,CDC42,PIK3CD,VAV2,PLXNB3,CNTN1,COL9A2,CRMP1,PPP2R5C,NCAN,PRKACB,DPYSL5,PSMD13,ITGAV,RGMA,SRGAP3,KCNQ2,DLG3,DNM2,RAP1GAP,RASGRF1,PAK5,L1CAM,RET,EFNA3" Pathway 1339121 Ion homeostasis BioSystems: REACTOME 1.62E-07 3.29E-04 2.65E-05 2.17E-04 14 56 "RYR1,SLC8A2,SLC8A3,ASPH,SLN,ATP1A2,ATP1A3,ATP2B2,AHCYL1,FXYD6,CAMK2A,CAMK2G,KCNJ11,ABCC9" Pathway 1270323 L1CAM interactions BioSystems: REACTOME 1.69E-07 3.44E-04 2.65E-05 2.17E-04 19 102 "SCN3A,SCN4B,ANK1,ANK2,ANK3,SH3GL2,SHTN1,SCN3B,NFASC,NCAM1,CNTN2,VAV2,CNTN1,NCAN,ITGAV,KCNQ2,DLG3,DNM2,L1CAM" Pathway 1268786 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell BioSystems: REACTOME 2.46E-07 5.01E-04 3.58E-05 2.93E-04 23 147 "ACTN2,ADCY2,GABBR1,GNG3,GNG4,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,CHRNB2,PRKACB,PRKCG,KCNJ4,KCNJ9,KCNJ10,DLG3,RASGRF1,EPB41L1" Pathway 698773 Circadian entrainment BioSystems: KEGG 3.23E-07 6.56E-04 4.37E-05 3.58E-04 18 96 "ADCY2,ADCYAP1R1,RYR1,GNAS,GNG3,GNG4,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIN1,GUCY1A2,GUCY1A1,PRKACB,PRKCG,NOS1AP,KCNJ9" Pathway 83065 Axon guidance BioSystems: KEGG 4.46E-07 9.06E-04 5.66E-05 4.64E-04 25 175 "SEMA6A,SEMA6C,NTNG1,LRRC4C,SLIT1,FYN,RND1,SEMA4A,ROBO3,UNC5D,CAMK2A,CAMK2G,CDC42,SEMA5B,PIK3CD,PLXNB3,PPP3CB,PRKCZ,DPYSL5,PTCH1,PARD6A,SRGAP3,PAK5,L1CAM,EFNA3" Pathway 1269341 Platelet homeostasis BioSystems: REACTOME 7.24E-07 1.47E-03 8.65E-05 7.09E-04 17 91 "MRVI1,FGR,SLC8A2,SLC8A3,ATP2B2,GNAS,GNG3,GNG4,GUCY1A2,P2RX7,GUCY1A1,PDE1A,PDE2A,PDE3B,PPP2R5C,LRP8,KCNMA1" Pathway 83069 Cell adhesion molecules (CAMs) BioSystems: KEGG 2.97E-06 6.03E-03 3.35E-04 2.74E-03 21 145 "MAG,NLGN4X,SELL,NTNG1,NLGN1,LRRC4C,CADM3,NFASC,NCAM1,CNTN2,JAM2,NLGN3,CADM1,NRXN1,NRXN2,NEGR1,CNTN1,VCAN,SDC3,ITGAV,L1CAM" Pathway 552665 Morphine addiction BioSystems: KEGG 3.53E-06 7.17E-03 3.78E-04 3.09E-03 16 91 "ADCY2,ADORA1,PDE8B,GABBR1,GNAS,GNG3,GNG4,CACNA1A,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PRKACB,PRKCG,KCNJ9" Pathway 1270325 Interaction between L1 and Ankyrins BioSystems: REACTOME 5.30E-06 1.08E-02 5.36E-04 4.39E-03 9 30 "SCN3A,SCN4B,ANK1,ANK2,ANK3,SCN3B,NFASC,KCNQ2,L1CAM" Pathway 1268799 "Unblocking of NMDA receptor, glutamate binding and activation" BioSystems: REACTOME 5.54E-06 1.13E-02 5.36E-04 4.39E-03 7 17 "ACTN2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIN1" Pathway 1268824 Inwardly rectifying K+ channels BioSystems: REACTOME 7.16E-06 1.46E-02 6.61E-04 5.42E-03 9 31 "GABBR1,ABCC8,GNG3,GNG4,KCNJ4,KCNJ9,KCNJ10,KCNJ11,ABCC9" Pathway P00027 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway PantherDB 1.22E-05 2.47E-02 1.08E-03 8.81E-03 17 111 "ADORA1,ADORA3,GNG3,GNG4,CACNA1A,CACNA1E,GRM3,CHRM1,CHRM4,RGS6,PRKCG,PRKCZ,KCNJ9,RAP1GAP,RGS7,RGS10,RASGRP2" Pubmed 24952961 A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Pubmed 5.78E-62 4.15E-57 4.15E-57 4.88E-56 185 1835 "TTYH1,SERPINA3,ABAT,ASIC1,MAPT,ACHE,CDHR1,APC2,MBP,ADGRV1,KCNIP2,ADCY2,DSCAML1,RXRG,ADCYAP1R1,DRAXIN,AGT,SCN4B,FGF1,FGF14,SEMA6A,MOBP,FOXG1,MOG,SOX6,FOXM1,SEMA6C,ANK3,ITSN1,APBA2,APC,NTNG1,BCAN,SORBS1,CLSTN1,AQP4,SLC1A2,SLC1A6,PKNOX2,DACH2,ASCL1,SCG3,LGI3,SLIT1,DLL3,ASTN1,SMARCE1,ADGRA1,ALDH4A1,ATP1A2,NRG3,FYN,DKK3,GABBR1,MYBPC1,MYT1L,B3GALT2,SOX5,CADM3,SOX10,GAD2,NKX6-2,DNER,FXYD6,NPAS3,NFASC,NCAM1,GFAP,GFRA1,RCOR2,FGF17,NEUROD1,NFIA,GLS,VAMP1,PCDH11X,NHLH1,ASTN2,NKX2-2,SEMA4A,ROBO3,CAMTA1,NODAL,UNC5D,BTRC,CNTN2,TBX15,CACNA1A,DDR1,TCF7L2,ZEB1,TCF12,GPR26,HAP1,CAMK2A,DDR2,AKNA,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GPR88,GRM3,TF,CCKBR,LEFTY2,TGFBR3,P2RX7,TIE1,PAH,DAAM2,MAEL,PAX6,CDH8,CDH10,HRH3,PCSK2,PDE1A,PDE1C,IGFN1,PDYN,GPR37L1,NTSR2,ADGRG1,CHRM1,CHRM4,CHRNB2,TLX1,CADM1,NRXN1,SEMA5B,UBTF,VAV2,PLXNB3,CNTN1,PRRX1,NECAB2,NSD2,FAT3,POU3F2,POU3F4,FEZ1,RBPJ,CTNND1,MAPK8,MAPK10,HES5,PROX1,ZBTB16,PSD,TOX,DPYSL5,PTCH1,ITGAV,CA10,PTHLH,LRP8,BLOC1S6,KCNA1,KCNA2,CDH20,KCNC1,PTPRZ1,NTM,ARNT2,KCNK2,HS3ST4,OLIG1,SLC17A6,RASGRF1,DBX2,L1CAM,CRTAC1,RET,RGS10,CACNG7,EFNA3,LMO1,CBLN2,EN2,OLIG2" Pubmed 28671696 Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Pubmed 1.29E-50 9.28E-46 4.64E-46 5.45E-45 119 916 "MAP6,ASIC1,APC2,CLIP1,RTN1,GPR158,LRRC7,UNC79,FOXG1,TRIM46,SFPQ,SGIP1,ANK3,USP28,PPFIA1,ITSN1,PKP4,SH3GL2,APC,DGKZ,SORBS1,JAKMIP3,SHTN1,SLC1A2,RPH3A,CCDC88A,SHANK2,SPHKAP,TAGLN3,ADGRA1,TNIK,KIF21B,ADGRB2,NFASC,NCAM1,CLASP2,ERBIN,NCDN,RCOR2,SEPT3,ARHGEF7,CAMSAP2,GOLGB1,CACNA1A,GPM6A,CACNA1E,CACNB2,ZEB1,CAMK2A,CAMK2G,NUMA1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GRM3,SHISA7,INA,P2RX7,TJP1,TNR,TNS1,PCDH8,CDH10,DCLK1,LGI1,MAGI1,PDE2A,PDE4B,HNRNPK,NLGN3,DLGAP3,NRXN1,CAMKV,CNTN1,CNRIP1,CRMP1,PPP3CB,RGS6,OSBPL3,NCAN,PRKACB,DOCK7,DZIP3,PRKCG,CTNND1,CTNND2,PROX1,ANKS1B,TUBB2B,SIRPA,DNAJC6,JAKMIP2,CEP170,MAGI2,KCNA1,KCNA2,KCNA4,PLPPR4,SRGAP3,KCNJ4,KCNJ10,KCNMA1,PEX5,DLG2,DLG3,KIF2A,DNM2,ABI1,DSCAM,PAK5,EEF1A2,ABI2,ELAVL3,ELAVL4,EPB41L1,EPB41L2" Pubmed 16710414 The DNA sequence and biological annotation of human chromosome 1. Pubmed 3.41E-42 2.45E-37 8.16E-38 9.59E-37 115 1031 "RIMKLA,SRARP,EXTL1,FAM43B,CSMD2,ARID1A,WLS,MDM4,F3,RXRG,CDC7,ADORA3,DRAXIN,TOMM40L,SCNN1D,LRRC7,BCAR3,FGR,HPCAL4,SEMA6C,SGIP1,CDC42BPA,NTNG1,ZCCHC17,CLSTN1,MIER1,SCMH1,GPR153,BRINP2,ASTN1,RCOR3,ALDH4A1,B3GALT2,KIF21B,CADM3,ILDR2,AHCYL1,NMNAT2,EMC1,ADGRB2,NASP,NFASC,NFIA,C1QC,CAMTA1,PSRC1,CNTN2,TBX15,NPPA,NRDC,AZIN2,PTBP2,SYT6,ATP13A2,CRB1,TGFBR3,MFSD2A,MAEL,TNFRSF1B,CDC42,IGSF21,TNR,PADI2,TPM3,CIART,ACOT7,CA14,NEGR1,MEAF6,BTF3L4,COL9A2,PRRX1,SPATA6,CHD5,PRKAB2,PRKACB,DOCK7,SDC3,FMN2,PKN2,PRKCZ,SLC45A1,PUM1,HES5,NOS1AP,BRINP3,RIMS3,GON4L,TOMM20,DNAJC6,CNIH3,PRDM2,CEP170,CSDE1,SMG7,KCND3,SV2A,KCNJ9,KCNJ10,SNX27,NKAIN1,BSDC1,CAMK1G,RFX5,RGS7,PHC2,TTLL7,VANGL2,RNF220,EFNA3,SH3GLB1,GPR61,ELAVL4,YY1AP1,EPB41" Pubmed 27507650 Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Pubmed 1.18E-36 8.46E-32 2.12E-32 2.49E-31 55 241 "LRRC7,ANK3,DGKZ,SORBS1,SLC1A2,SHANK2,ADGRA1,TNIK,ADGRB2,NFASC,NCAM1,ERBIN,NCDN,SEPT3,ARHGEF7,GPM6A,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,INA,DCLK1,LGI1,PDE2A,PDE4B,NLGN3,DLGAP3,NRXN1,CNTN1,CNRIP1,PPP3CB,NCAN,PRKACB,PRKCG,CTNND1,CTNND2,ANKS1B,TUBB2B,SIRPA,DNAJC6,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ10,DLG2,DLG3,ABI1,EPB41L1,EPB41L2" Pubmed 24154525 Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Pubmed 1.73E-35 1.24E-30 2.48E-31 2.92E-30 63 348 "EPS8,ABAT,MBP,ADGRV1,ATAT1,WLS,ADARB2,FABP7,SEMA6A,MOBP,MOG,ANK1,BCAN,AQP4,SLC1A2,SLC14A1,CADPS,ASCL1,SCG3,CSPG5,ADGRA1,ATP1A2,MYBPC1,GAD2,DNER,FXYD6,GFAP,NEUROD1,ACSBG1,NFIA,MLC1,C1QC,KAZN,GNAS,SYT6,VSTM2A,GRIA4,DAAM2,CD81,PADI2,GPR37L1,ADGRG1,PLEKHB1,HEPACAM,SERPINE2,VAV2,NECAB2,NXPH1,NRSN1,HES5,RIMS3,DPYSL5,PTHLH,ELMO1,KCNC1,PTPRZ1,ARNT2,KCNK1,CAMK1G,RGS10,CBLN2,RCAN2,SEZ6" Pubmed 17114649 Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Pubmed 5.47E-33 3.93E-28 6.55E-29 7.70E-28 59 330 "MAPT,RTN3,RTN1,ADD3,AMER2,LRRC7,SGIP1,ITSN1,PKP4,APC,BCAN,SORBS1,BCAS1,SLC1A2,MADD,SHANK2,ARFGAP1,ATP1A2,EIF4G3,ATP2B2,GABBR1,NCAM1,ARHGEF7,GNG3,ADGRL3,CACNA1A,GPM6B,CACNA1E,CAMK2A,CAMK2G,BRSK2,GRIN1,DCLK1,GPR37L1,PRKACB,FMN2,PRKCG,CTNND1,CTNND2,MAPK10,RIMS3,SYTL2,TOMM20,DNAJC6,MAGI2,KCNA2,KCNA4,SV2A,SRGAP3,KCNMA1,KCNQ2,DLG2,ABI1,RASGRF1,RTN4,L1CAM,RGS7,SLC4A10,EPB41L1" Pubmed 12693553 Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 3.62E-32 2.60E-27 3.72E-28 4.37E-27 63 395 "RBM10,SLC25A25,CSMD3,KLHL32,ADCY2,GRAMD1B,CHST15,LRRC7,PPM1E,DOCK10,SORBS1,NLGN1,LRRC4C,ZNF365,MADD,CADPS,SPHKAP,SLIT1,BRINP2,MEGF11,USP33,SON,TNIK,KIF1B,RAP1GAP2,ERBIN,DCAF5,NCDN,KIRREL3,PHLDB1,GANAB,FAM168A,MLC1,CAMTA1,CAMSAP2,ADGRL3,ACSL6,CAMK2A,PSD3,DAAM2,SEZ6L,NEGR1,PLXNB3,TENM4,DOCK7,DZIP3,ARHGEF4,PUM1,KIAA0513,RIMS3,GON4L,DNAJC6,CSDE1,MAGI2,ZC3H11A,SV2A,SRGAP3,RABGAP1L,SNX27,DLG3,ZYG11B,NUP214,EPB41L1" Pubmed 16385451 A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Pubmed 5.74E-30 4.12E-25 5.16E-26 6.06E-25 62 416 "ZFYVE27,CDHR1,KCNIP2,ADARB2,ADD3,SORCS1,CHST15,GPR158,ANK3,ANXA7,GPAM,TACC2,SORBS1,JAKMIP3,SHTN1,ZNF365,RUFY2,SLIT1,SORCS3,ADGRA1,PHYHIPL,ZCCHC24,GAD2,ZSWIM8,GFRA1,NODAL,BTRC,CACNB2,TCF7L2,ZEB1,CAMK2G,INA,TLL2,NEURL1,ARHGAP19,LGI1,HPSE2,PFKFB3,ARHGAP22,CCSER2,DNAJC12,ACBD5,ATRNL1,CALY,USP54,PSD,WBP1L,ITIH2,PTPRE,PCDH15,KCNMA1,ABI1,FAM13C,CRTAC1,RET,RGR,JMJD1C,RGS10,ZNF248,SEC61A2,SLC39A12,ARHGAP12" Pubmed 28706196 Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. Pubmed 9.27E-30 6.65E-25 7.39E-26 8.69E-25 50 259 "MAP6,LRRC7,AMPH,ANK3,PPFIA1,PKP4,PPM1E,DGKZ,SORBS1,NLGN1,SHANK2,TNIK,ADGRB2,NCAM1,NCDN,GNAS,CACNA1E,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIN1,GRM3,SHISA7,INA,TNR,CDH10,DCLK1,PRMT8,NLGN3,DLGAP3,CNRIP1,CRMP1,PPP3CB,NCAN,PRKACB,PRKCG,PKN2,CTNND2,MAPK10,ANKS1B,KCNA4,SRGAP3,AK5,KCNJ10,DLG2,DLG3,EPB41L1,EPB41L2" Pubmed 28611215 Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Pubmed 1.01E-25 7.25E-21 7.25E-22 8.52E-21 112 1489 "ABAT,MAPT,MBP,RTN3,ADGRV1,ATAT1,ARID1A,MDM4,KCNIP2,SNX30,GPR158,KIAA1109,PLA2G6,LRRC7,SEMA6A,CDC42BPA,ANK3,RASA3,FOLH1,ANXA7,MAGI3,SLITRK3,ST3GAL3,STK32C,SHTN1,SFMBT2,NBPF1,MSRA,PKNOX2,SHANK2,NAXD,ASPH,RCOR3,IGSF9B,NRG3,EIF4G3,NMNAT2,NEK6,KIF1B,STARD10,NFASC,CLASP2,ERBIN,NCDN,INKA2,PHLDB1,FAM168A,NFIA,ABCC8,ZNF638,OS9,ASTN2,LUZP2,DCLK2,GNAS,CAMTA1,GNG4,GOLGB1,PRUNE2,ATF7,DDR1,CACNB2,TCF7L2,PTBP2,GRIK2,GUCY1A1,TJP1,HPS5,RBFOX2,MAGI1,PDE3B,ADGRG1,TMPRSS5,CASC2,TMEFF2,NLGN3,VAV2,BEST1,BTF3L4,SPATA6,NSD2,CHD1L,MICAL2,PRKACB,SDC3,PRKCZ,ARHGEF4,CTNND1,ZBTB16,DPYSL5,SPIRE1,ZNF385B,HP1BP3,LRP8,CEP170,CSDE1,ZC3H11A,SMG7,PTPRE,KCND3,C1orf109,KCNMA1,CAB39L,RAD52,DPP6,DTNA,JMJD1C,ZNF248,EEF1A2,BSCL2,EPB41,EPB41L1" Pubmed 15226823 Genomic analysis of mouse retinal development. Pubmed 3.31E-24 2.37E-19 2.16E-20 2.54E-19 85 961 "TTYH1,CDHR1,ATAT1,ADAR,RTN1,FABP7,GRAMD1B,KIAA1109,C1QTNF4,RASA3,APC,TACC2,CLSTN1,SLC1A7,SLC6A9,ARFGAP2,CADPS,SPHKAP,LGI3,SLIT1,SNAP25,SNCB,PHYHIPL,DKK3,GABBR1,USP33,ZSWIM8,SALL3,TTC9B,STARD10,CPLX2,ERBIN,RCOR2,NEUROD1,NHLH1,ROBO3,CDK5R2,TMEM136,DDR1,LRIT2,CACNB2,TCF7L2,TCF12,EML4,BRSK2,PSD3,RFFL,USP2,CELF3,CD81,PAX6,IGSF21,DCLK1,TPD52,ACOT7,ADGRG1,CHGA,CHRM1,DUSP26,CADM1,NRXN2,NOMO2,BTF3L4,PMS2,PRRX1,BTBD17,RBPJ,PUM1,HES5,ZNF385B,LRP8,MED24,SRGAP3,RABGAP1L,KCNK1,NKAIN1,FAM57B,RALGDS,ABI1,DTNA,SLC6A15,PHC2,EPB41,EPB41L2,SEZ6" Pubmed 18519826 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Pubmed 1.94E-19 1.39E-14 1.16E-15 1.36E-14 26 101 "ADCY2,DSCAML1,SORCS1,TACC2,SLC1A2,ASTN1,TMEM108,SNAP25,NRG3,TNIK,SOX5,NPAS3,NELL1,LUZP2,KAZN,CACNB2,GRIK2,MAGI1,NECAB2,OLFM3,PTPRD,KCNK2,PCDH15,KCNN3,DPP6,DSCAM" Pubmed 16713569 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Pubmed 5.28E-19 3.79E-14 2.92E-15 3.43E-14 59 608 "RBM10,MBP,CEND1,ACTN2,WAC,ADORA1,PDZD4,PPFIA1,SH3GL2,APBB1,GAS7,SYBU,SCMH1,SLIT1,ATP1A3,FYN,MEGF11,DKK3,ZSWIM8,LMO3,NELL1,KAZN,CAMSAP2,NPPA,HAP1,PTBP2,NUDT21,TMEM25,AIFM1,CELF3,C1orf94,PCDH8,RBFOX2,ARHGAP19,PRMT8,ZMYND8,ACOT7,HNRNPK,KIAA1549L,FADS2,CCDC136,C11orf49,NECAB2,IFFO1,DZIP3,PRKCG,USP54,PUM1,PMEPA1,ARNT2,ATN1,BEND5,DTNA,USH1C,PHC2,RNF220,YY1AP1,PLEKHO1,EPB41L2" Pubmed 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 9.12E-19 6.55E-14 4.68E-15 5.50E-14 41 301 "ACHE,ACTN2,ADCYAP1R1,ADORA3,AGT,NLGN1,SLC1A2,SLC1A6,SLC1A7,SLC6A9,ASTN1,SNAP25,NRG3,GABBR1,GAD2,NCAM1,NEUROD1,ASTN2,CNTN2,NPPA,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CCKBR,PAH,PDYN,NTSR2,CHRM1,CHRNB2,NRXN1,NRXN2,CNTN1,MAGI2,DLG2,DLG3,SLC17A6,L1CAM" Pubmed 16169070 A human protein-protein interaction network: a resource for annotating the proteome. Pubmed 8.81E-18 6.32E-13 4.22E-14 4.96E-13 104 1678 "DPF1,EPS8,RBM10,SYNDIG1,ACTN2,ECSIT,RXRG,DISP3,ACTL6B,BBOX1,FOXG1,TRIM46,SFPQ,ITSN1,PKP4,SH3GL2,DGKZ,DGKD,TACC2,SYBU,ST3GAL3,SLC1A6,NSG2,CADPS,SCMH1,ARFGAP1,SNAP25,SNCB,GABBR1,USP33,KIF1B,ADGRB2,FXYD6,NASP,RCOR2,SEPT3,ARHGEF7,OS9,GOLGB1,WWC1,DDR1,TCF12,HAP1,NUDT21,EML4,TF,TMEM9,AIFM1,CELF3,CD81,CDK11B,CDC42,IGSF21,CDH10,MAGI1,HMGB1,MS4A7,NRXN2,CAMKV,PIK3CD,UBTF,CCSER2,C11orf49,COL9A2,PACSIN1,CRMP1,SNCAIP,FEZ1,PHACTR3,MAPK10,ZBTB16,PSD,DPYSL5,PHYHIP,TOMM20,TUBB2B,ITIH2,COPS7A,RGMA,CSDE1,STMN4,BLOC1S6,KCNA4,SMG7,PLPPR4,PTPRO,AK5,TMCC2,PEX5,KCNQ2,DNM2,PLEKHB2,RAP1GAP,ATN1,BEND5,RTN4,L1CAM,BSDC1,FAM135B,ARHGEF10L,PHC2,EFNA3,RASGRP2,SEZ6" Pubmed 21900206 A directed protein interaction network for investigating intracellular signal transduction. Pubmed 1.05E-17 7.52E-13 4.70E-14 5.53E-13 81 1123 "RABEPK,EPS8,RXRG,ACTL6B,FHL1,HPCAL4,TRIM46,AMPH,ASRGL1,ITSN1,ANXA7,PKP4,SH3GL2,APBA2,APBB1,DGKZ,DGKD,PAAF1,RUFY2,NSG2,ARFGAP1,TMEM108,EIF4G3,FYN,KIF21B,NASP,SEPT3,ACSBG1,BTRC,PSRC1,WWC1,GPM6A,DDR1,HAP1,NUDT21,ATP13A2,FBXL16,CELF3,CDC42,IGSF21,TNS1,PCDH8,TPM3,ZMYND8,HMGB1,CHGA,NRXN2,SEMA5B,NOMO2,NMT2,CCSER2,CCDC136,CNTN1,C11orf49,MICAL1,CRMP1,SNCAIP,FEZ1,PHACTR3,RBPJ,DOCK7,PKN2,PRKCZ,CTNND2,MAPK8,EDRF1,KIAA0408,MASP1,ZBTB16,TUBB2B,MED24,PTPRO,PEX5,DNM2,RAP1GAP,RTN4,JMJD1C,PHC2,EEF1A2,YY1AP1,SEZ6" Pubmed 16985003 Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Pubmed 6.25E-16 4.48E-11 2.64E-12 3.10E-11 26 137 "KCNIP2,SCN3A,ATP1A2,SCN3B,ABCC8,CACNA1A,CACNA1E,CACNB2,P2RX7,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9" Pubmed 16452087 Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Pubmed 2.82E-15 2.02E-10 1.13E-11 1.32E-10 31 214 "RPL38,MAPT,MBP,RTN3,AMER2,LRRC7,SGIP1,ANK1,ITSN1,PKP4,SORBS1,BCAS1,SHANK2,GABBR1,NCAM1,CLASP2,GFAP,SEPT3,CACNA1E,CAMK2G,DCLK1,HNRNPK,TJP2,CTNND2,FAM131B,PTPRZ1,PAK5,EEF1A2,SLC4A10,EPB41L1,EPB41L2" Pubmed 23251661 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Pubmed 8.51E-15 6.11E-10 3.21E-11 3.78E-10 62 817 "ADGRV1,GALNT13,ADORA3,LRRC7,PKP4,SH3GL2,MAGI3,TACC2,SORBS1,PKNOX2,SHANK2,SLIT1,IGSF9B,WDR11-AS1,NRG3,NMNAT2,CPLX2,NELL1,ASTN2,CDK5R2,CACNB2,CAMK2A,SYT6,PSD3,GRIA1,GRIK2,GUCY1A2,DCLK1,PCSK2,HPSE2,CADM1,SLC36A4,NXPH1,POU3F2,TENM4,RIMS4,PLD5,NOS1AP,DPYSL5,ANKS1B,TOMM20,PLPPR5,PMEPA1,PRTFDC1,MAGI2,CDH20,PTPRD,PARD6A,NTM,NAV2,KCNN3,DLG2,HS3ST4,SLC25A48,DSCAM,PAK5,ABCC9,RGS7,ARHGEF10L,TTLL7,VWA5A,ELAVL4" Pubmed 8619474 "A ""double adaptor"" method for improved shotgun library construction." Pubmed 1.40E-14 1.01E-09 4.97E-11 5.84E-10 50 569 "MEG3,ADCY2,SEMA6C,ANK2,APBA2,APC,SLC1A2,SHANK2,BRINP2,B3GAT1,DKK3,AHCYL1,NFASC,AJAP1,ACSBG1,PCDH11X,KAZN,EML4,OPCML,TJP1,AIFM1,KCNK10,DCLK1,ARHGAP19,ARHGAP22,DLGAP3,CCSER2,FLRT1,FTO,MEAF6,NECAB2,MICAL2,CTNND2,MAPK10,KIAA0513,WBP1L,PLPPR5,TUBB2B,CNIH3,CSDE1,BLOC1S6,WIPF2,CALN1,FAM13C,FAM135B,ATL1,ARHGAP12,LINC00599,BSCL2,EPB41L2" Pubmed 19165527 Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Pubmed 1.45E-14 1.04E-09 4.97E-11 5.84E-10 20 84 "SERPINA3,MAP6,ERMN,MOG,PKP4,SH3GL2,SORBS1,CADM3,HNRNPK,ATCAY,PRKCG,CTNND2,TUBB2B,SIRPA,DNAJC6,HP1BP3,RTN4,L1CAM,RLBP1,EPB41L1" Pubmed 16959763 Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Pubmed 6.25E-14 4.49E-09 2.04E-10 2.40E-09 24 138 "MAP6,MBP,ARID1A,GRAMD1B,SFPQ,MADD,CCDC88A,ATP2B2,GFAP,ARHGEF7,CAMSAP2,CAMK2A,CAMK2G,PSD3,INA,PADI2,PDE1A,CAMKV,PPP3CB,PRKACB,DOCK7,RIMS3,AK5,KIF2A" Pubmed 9455484 Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. Pubmed 1.52E-13 1.09E-08 4.73E-10 5.56E-09 16 54 "CDC42BPA,KIF21B,NMNAT2,PLCH2,CHD5,SDC3,PRKCZ,NOS1AP,DNAJC6,CEP170,PLPPR4,RABGAP1L,TMCC2,SNX27,RAP1GAP,SH3GLB1" Pubmed 11544199 Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Pubmed 1.97E-13 1.41E-08 5.89E-10 6.92E-09 65 947 "PRR5L,MAP6,LGR4,WLS,KLHL32,KIAA1109,SFPQ,ANK3,PPFIA1,ITSN1,APC,DGKZ,TACC2,MIER1,MADD,ARHGAP5,ARFGAP1,MYT1L,SALL3,NASP,CLASP2,ERBIN,DCAF5,NCDN,NEUROD1,FAM168A,ZNF638,CAMTA1,GOLGB1,CACNB2,NRDC,PTBP2,P2RX7,DCLK1,PDE4B,TUB,HNRNPK,NLGN3,ANLN,PIK3CD,UBTF,CCSER2,TJP2,C11orf49,PMS2,CRMP1,FEZ2,OSBPL3,ATRNL1,VCAN,RBPJ,DZIP3,FMN2,PRKCZ,PUM1,SPIRE1,PTCH1,PRDM2,COPS7A,MED24,ZC3H11A,KCNH1,SNX27,KIF2A,DNM2" Pubmed 16632597 Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Pubmed 3.63E-13 2.61E-08 1.04E-09 1.23E-08 15 48 "MAPT,NSG2,ASCL1,SCG3,TAGLN3,SOX10,GFRA1,GNG3,TMEFF2,CADM1,CRMP1,MAPK10,L1CAM,RET,ELAVL4" Pubmed 9110174 Large-scale concatenation cDNA sequencing. Pubmed 5.62E-13 4.03E-08 1.55E-09 1.82E-08 47 563 "MEG3,ADCY2,SEMA6C,ANK2,APBA2,APC,SLC1A2,SHANK2,BRINP2,B3GAT1,DKK3,AHCYL1,NFASC,AJAP1,ACSBG1,PCDH11X,KAZN,EML4,OPCML,TJP1,AIFM1,KCNK10,DCLK1,ARHGAP19,DLGAP3,FLRT1,FTO,MEAF6,NECAB2,MICAL2,CTNND2,MAPK10,KIAA0513,WBP1L,PLPPR5,TUBB2B,CNIH3,CSDE1,BLOC1S6,CALN1,FAM13C,FAM135B,ATL1,ARHGAP12,LINC00599,BSCL2,EPB41L2" Pubmed 15146195 Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Pubmed 8.10E-13 5.81E-08 2.15E-09 2.53E-08 14 42 "MAG,MBP,MOG,APBB1,CLSTN1,ATP1A3,ATP2B2,CADM3,NCAM1,OPCML,CNTN1,NTM,DPP6,L1CAM" Pubmed 17953485 Regulatory pathway analysis by high-throughput in situ hybridization. Pubmed 8.43E-13 6.05E-08 2.16E-09 2.54E-08 19 91 "TTYH1,FGF14,BCAN,ARHGAP5,GAD2,NEUROD1,PRUNE2,TCF7L2,SYT6,GRIA1,GRIN1,GRM3,PAX6,CDH8,PDE1C,HEPACAM,POU3F4,NKAIN4,RASGRF1" Pubmed 25936505 Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Pubmed 1.07E-12 7.66E-08 2.64E-09 3.10E-08 13 35 "FABP7,ASCL1,SLIT1,SOX10,NFIA,NKX2-2,PAX6,RBPJ,PRKCZ,HES5,PTCH1,DBX2,OLIG2" Pubmed 16512683 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. Pubmed 1.16E-12 8.35E-08 2.78E-09 3.27E-08 24 157 "MAP6,MBP,RTN3,TUBB4A,TRIM46,AMPH,SH3GL2,BCAS1,RPH3A,KIF21B,CLASP2,SEPT3,ACSBG1,CAMK2A,DCLK1,TPD52,PDE1A,CAMKV,PPP3CB,PTPRE,SV2A,RAP1GAP,RTN4,EPB41L2" Pubmed 15572359 Proteomic analysis of in vivo phosphorylated synaptic proteins. Pubmed 1.36E-12 9.74E-08 3.14E-09 3.70E-08 15 52 "MAPT,MBP,RTN1,SGIP1,PKP4,AHCYL1,NFASC,NCAM1,ARHGEF7,CAMK2A,FMN2,CTNND2,FAM131B,ATL1,EPB41L1" Pubmed 23482494 Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord. Pubmed 1.72E-12 1.24E-07 3.87E-09 4.55E-08 12 29 "MBP,APC,ASCL1,SOX10,GFAP,NFIA,NKX2-2,MMD2,PAX6,PTCH1,FGFBP3,OLIG2" Pubmed 27149841 Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. Pubmed 2.06E-12 1.48E-07 4.49E-09 5.28E-08 11 23 "MAG,MBP,MOG,APC,GFAP,NKX2-2,MYRF,PAX6,OPALIN,OLIG1,OLIG2" Pubmed 15164054 The DNA sequence and comparative analysis of human chromosome 10. Pubmed 2.54E-12 1.82E-07 5.36E-09 6.30E-08 35 346 "ZFYVE27,ADARB2,WAC,SORCS1,CHST15,GPR158,HOGA1,GOLGA7B,GPAM,TACC2,JAKMIP3,STK32C,ZNF365,SFMBT2,RUFY2,SORCS3,ADGRA1,NRG3,ZCCHC24,ENKUR,STOX1,PRLHR,CAMK2G,TLL2,NEURL1,ARHGAP19,LGI1,HPSE2,NMT2,DNAJC12,USP54,WBP1L,KCNMA1,ABI1,FGFBP3" Pubmed 12168954 Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. Pubmed 2.81E-12 2.02E-07 5.77E-09 6.79E-08 28 225 "ADGRV1,DSCAML1,GPR158,DOCK10,CADPS,SLIT1,MYT1L,TNIK,NFASC,ERBIN,PHLDB1,MLC1,CAMTA1,PRUNE2,PSD3,HPS5,NRXN1,NRXN2,PACSIN1,TENM4,CHD5,ARHGEF4,TOX,SMG7,SRGAP3,TMCC2,NAV2,RBM12" Pubmed 19723505 SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch. Pubmed 4.48E-12 3.22E-07 8.93E-09 1.05E-07 12 31 "MBP,SOX6,ASCL1,DLL3,SOX1,SOX10,GFAP,NFIA,NKX2-2,PAX6,HES5,OLIG2" Pubmed 18455991 Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Pubmed 5.86E-12 4.21E-07 1.14E-08 1.34E-07 8 10 "SLIT1,NKX6-2,GFAP,NFIA,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 28558017 A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. Pubmed 7.99E-12 5.74E-07 1.51E-08 1.78E-07 17 79 "SEMA6A,NTNG1,CLSTN1,IGSF9B,DNER,GFRA1,KIRREL3,PCDH11X,ASTN2,CDH8,CDH10,CADM1,FAT3,TENM4,LRP8,RET,CBLN2" Pubmed 8125298 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Pubmed 8.41E-12 6.04E-07 1.55E-08 1.82E-07 97 1883 "MAG,ACHE,RBM10,RTN3,ATAT1,ARID1A,MDM4,ADD3,WAC,FOXRED2,AGT,KIAA1109,FHL1,TRIM46,SELL,ASRGL1,ANK1,ANXA7,GAS7,DGKZ,BCAS1,PAAF1,CLSTN1,USP16,AQP4,ARFGAP1,NAXD,ALDH4A1,SNAP25,CCDC181,ATP1A2,ATP1A3,EIF4G3,DKK3,GABBR1,USP33,SOX5,NASP,ALDH1L1,GFAP,POPDC3,GNAS,ROBO3,TCF7L2,CAMK2G,DDR2,NUCB1,GPR88,CYB561A3,TF,OMG,CCKBR,TMEM25,TGFBR3,P2RX7,TIE1,TPD52,ZMYND8,GPR37L1,CHGA,CHI3L2,TMEFF2,GDAP1L1,SERPINE2,NOMO2,MEAF6,MICAL1,PRRX1,CHD1L,PTPA,NKAIN4,IGSF1,NRSN1,MAPK10,PUM1,SYTL2,GON4L,PSMD13,PLPPR1,ITIH2,PRTFDC1,STMN4,PEX5,PLEKHB2,BSDC1,USH1C,RFX5,ATL1,TTLL7,RNF220,SH3GLB1,LPAR6,YY1AP1,BSCL2,PLEKHO1,LRRC23,SEZ6" Pubmed 24613359 Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Pubmed 1.20E-11 8.59E-07 2.15E-08 2.52E-07 14 50 "SLITRK1,LRRTM4,SLITRK3,NLGN1,CLSTN1,ADGRB2,ADGRL3,GRIA1,LRTM2,NRXN1,NRXN2,FLRT1,LRRTM3,DLG2" Pubmed 23055939 A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. Pubmed 1.23E-11 8.81E-07 2.15E-08 2.53E-07 17 81 "SGIP1,SORBS1,MADD,RUFY2,CADPS,SCG3,SNAP25,SCN3B,EMC1,KIF1B,CLASP2,CACNB2,PTBP2,PPP3CB,KCNQ2,DTNA,SH3GLB1" Pubmed 14621295 Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.33E-11 9.51E-07 2.27E-08 2.66E-07 42 508 "ADGRV1,PLEKHG5,SEMA6C,CDC42BPA,USP28,CACHD1,MIER1,KIAA1614,URGCP,CCDC88A,CAPRIN2,ATP1A2,KIF21B,NMNAT2,EMC1,NFASC,ACSBG1,ARHGEF7,CECR2,AKNA,HPS5,PADI2,NRXN2,SEMA5B,CCSER2,FTO,PACSIN1,NSD2,PLCH2,CHD5,SDC3,IGSF1,SPIRE1,TOMM20,SMG7,PLPPR4,NAV2,RALGDS,RTN4,ARHGEF10L,VANGL2,RBM12" Pubmed 24324551 Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. Pubmed 1.83E-11 1.31E-06 3.03E-08 3.57E-07 21 134 "SYT9,LOC101928524,ADARB2,GPR158,LRRC4C,NPAS3,RAP1GAP2,NCAM1,ALDH1L1,NELL1,KAZN,CAMTA1,DIRAS1,GRIA4,RGS6,CTNND2,MAGI2,PTPRD,DLG2,HS3ST4,WIPF2" Pubmed 19906978 Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. Pubmed 1.86E-11 1.34E-06 3.03E-08 3.57E-07 23 163 "SYT9,FABP7,FGF14,AQP4,LRRC55,NCAM1,SMOC1,GFAP,GFRA1,NEUROD1,ROBO3,SYT6,OPCML,SPX,CDH8,ADGRG1,VAV2,NECAB2,RGS6,PLCH2,KCNMA1,DPP6,RFX4" Pubmed 29031500 Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Pubmed 2.45E-11 1.76E-06 3.90E-08 4.59E-07 28 246 "SLITRK1,RXRG,FGF1,SEMA6A,SOX6,NTNG1,SLITRK3,ASCL1,CSPG5,SLIT1,MYT1L,SOX5,SOX10,GFRA1,UNC5D,TCF7L2,ZEB1,TCF12,FLRT1,PTCH1,LRP8,PTPRO,PTPRZ1,ARNT2,L1CAM,RET,ELAVL3,ELAVL4" Pubmed 19030180 Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. Pubmed 4.33E-11 3.11E-06 6.76E-08 7.95E-07 20 126 "RXRG,FOXG1,ASCL1,SLIT1,SOX1,SOX10,NKX6-2,SALL3,NKX2-2,GUCY1A1,PAX6,CDH8,POU3F2,POU3F4,HES5,PROX1,OLIG1,SLC17A6,LMO1,OLIG2" Pubmed 15345747 Phosphoproteomic analysis of the developing mouse brain. Pubmed 5.42E-11 3.89E-06 8.24E-08 9.69E-07 27 237 "MAPT,CLIP1,AMER2,AMPH,ITSN1,APBA2,SYBU,TNIK,KIF21B,NCAM1,CLASP2,CAMSAP2,PTBP2,CDK11B,DCLK1,CAMKV,CRMP1,FEZ1,CTNND2,MAPK8,ITIH2,PARD6A,TMCC2,KIF2A,RTN4,ARHGAP12,EPB41L1" Pubmed 17145500 PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Pubmed 5.51E-11 3.96E-06 8.24E-08 9.69E-07 19 114 "MAG,MBP,SLITRK1,SEMA6A,SEMA6C,NTNG1,SLITRK3,LRRC4C,CADM3,NCAM1,SEMA4A,TMPRSS5,CADM1,SEMA5B,PLXNB3,PRKCG,CADM2,L1CAM,EFNA3" Pubmed 12975309 "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Pubmed 8.32E-11 5.97E-06 1.22E-07 1.43E-06 61 987 "WLS,SLC25A25,SLITRK1,GRAMD1B,ADORA3,NLGN4X,DRAXIN,LRRTM4,BCAR3,PI16,NTNG1,BCAN,LRRC4C,SCG3,LGI3,TMEM108,IGSF9B,PHYHIPL,MEGF11,DKK3,CADM3,DNER,FXYD6,FGF17,KIRREL3,LUZP2,SEMA4A,UNC5D,CNDP1,VWC2,CLEC9A,TMEM25,MFSD2A,TMEM9,SEZ6L,LGI1,ADGRG1,SCRG1,CA14,TMEFF2,JAM2,CADM1,SEMA5B,NEGR1,FLRT1,SLC25A27,MFSD4A,PNKD,ECE2,LRRTM3,CA10,OLFM3,NTM,TMCC2,KCNQ2,ATG16L1,SUSD4,BSDC1,SIDT2,PIANP,CBLN2" Pubmed 19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Pubmed 1.02E-10 7.35E-06 1.47E-07 1.73E-06 19 118 "ACHE,ADCY2,SLC1A2,SLC1A6,SNAP25,GAD2,GLS,SYT4,CAMK2A,GRIA1,GRIA2,GRIA4,GRIN1,GRM3,HRH3,CHRM1,CHRM4,CHRNB2,SLC17A6" Pubmed 22357600 The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Pubmed 1.08E-10 7.74E-06 1.52E-07 1.78E-06 11 31 "ADD3,CADPS,SNAP25,DKK3,CAMTA1,RBFOX2,CHD5,LRP8,CSDE1,KCND3,KCNQ2" Pubmed 20936779 A human MAP kinase interactome. Pubmed 1.72E-10 1.23E-05 2.37E-07 2.79E-06 39 486 "SFPQ,CDC42BPA,ANK3,ITSN1,ANXA7,APC,GAS7,SORBS1,STK32C,SLC1A2,MADD,CCDC88A,RAP1GAP2,ERBIN,GFAP,RGL1,ARHGEF7,OS9,GOLGB1,CDC42,TNS1,RBFOX2,TPM4,MAGI1,HNRNPK,KIAA1549L,PACSIN1,PRKCZ,ARHGEF4,MAPK10,CSDE1,BLOC1S6,NAV2,WIPF2,RALGDS,PAK5,NUP214,YY1AP1,EPB41L2" Pubmed 16148239 Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression. Pubmed 1.91E-10 1.37E-05 2.59E-07 3.04E-06 7 9 "MBP,APC,ASCL1,SOX10,NKX2-2,OLIG1,OLIG2" Pubmed 16284245 Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Pubmed 2.14E-10 1.54E-05 2.85E-07 3.35E-06 19 123 "SYT9,SEMA6A,FOXG1,NTNG1,SLIT1,DKK3,SOX5,NEUROD1,NKX2-2,ROBO3,UNC5D,PAX6,CDH8,CDH10,SERPINE2,SEMA5B,PLXNB3,PTCH1,ARNT2" Pubmed 26182416 Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Pubmed 4.39E-10 3.15E-05 5.73E-07 6.73E-06 9 20 "GFAP,NEUROD1,UNC5D,PAX6,POU3F2,L1CAM,ELAVL3,ELAVL4,OLIG2" Pubmed 17081983 "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Pubmed 5.26E-10 3.78E-05 6.74E-07 7.93E-06 80 1546 "EPS8,ACLY,RBM10,MBP,RTN3,ARID1A,ADAR,CLIP1,ADD3,WAC,BCAR3,SFPQ,ANK2,PPFIA1,ITSN1,PKP4,SH3GL2,DOCK10,APC,DGKZ,API5,MIER1,SHANK2,SCMH1,RCOR3,EIF4G3,PALLD,SON,ZCCHC24,KIF1B,NASP,ERBIN,PHLDB1,NFIA,ARHGEF7,ZNF638,PRUNE2,ATF7,ZEB1,EML4,CAMK2G,NUMA1,TJP1,ZFP91,CDK11B,TNS1,TPD52,TPM3,ZMYND8,HNRNPK,ANLN,TJP2,MICAL1,NSD2,MED1,SF1,CHD5,CALY,PKN2,PRKCZ,CTNND1,PUM1,RIMS3,TOMM20,CA10,PRDM2,CEP170,CSDE1,MED24,ZC3H11A,SMG7,NAV2,ABI1,ATN1,RTN4,L1CAM,NUP214,SIDT2,RBM12,EPB41L1" Pubmed 27626380 High-throughput discovery of novel developmental phenotypes. Pubmed 5.71E-10 4.10E-05 7.20E-07 8.46E-06 83 1633 "MAG,MAPT,PAQR6,ADGRV1,ADAR,RTN1,SLITRK1,ADCYAP1R1,GPR158,ASIC4,BBOX1,ELMOD1,HPCAL4,SGIP1,PKP4,SH3GL2,CLSTN1,USP16,RPH3A,SLC2A5,SLC8A3,SLIT1,TMEM108,CCDC181,ATP1A3,GAD2,KIF1B,STARD10,GART,DNER,ALDH1L1,SMOC1,AJAP1,MLC1,RHBDL3,POPDC3,BTRC,ADGRL3,TMEM136,GPR17,TMEM151B,VXN,GRM3,USP2,MFSD2A,FBXL16,P2RX7,DAAM2,PC,PADI2,CDH10,SEZ6L,ARHGAP19,CHRNB2,ZBED5,JAM2,NRXN1,NEGR1,COL9A2,SPATA6,CP,PTPA,CSF3R,PRKAB2,RAB39A,PLD5,USP54,RIMS3,LRRTM3,SIRPA,KCNA1,KCNJ9,SNX27,CAB39L,PARP11,C12orf4,ATN1,RLBP1,FGFBP3,LPAR6,C2orf80,TMEM100,EPB41" Pubmed 21832049 "Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein." Pubmed 5.83E-10 4.19E-05 7.22E-07 8.49E-06 92 1891 "MAG,ZFYVE27,ACLY,SRARP,ATAT1,RTKN,MDM4,KLHL32,WAC,CDC7,ERMN,ACTL6B,BCAR3,MOBP,PDZD4,RASA3,SH3GL2,GPAM,ZCCHC17,ZNF365,MIER1,ARFGAP1,ASPH,RCOR3,ALDH4A1,SNAP25,SOX5,NMNAT2,STARD10,CPLX2,SPART,NDUFA5,GFAP,INKA2,RGL1,GJB1,ACSBG1,DDHD2,PSRC1,CNDP1,DIRAS1,SYT6,SPX,USP2,DCLK1,PDE1A,CIART,PDYN,SLC22A6,CAMKV,NMT2,CCSER2,DNAJC12,NSD2,ATCAY,ETNPPL,PNKD,PTPA,PPP2R5C,RIMS4,RBPJ,RAB39A,PRKCG,CTNND1,MAPK8,MAPK10,NOS1AP,KIAA0513,ANKS1B,HP1BP3,MED24,BLOC1S6,OLFM3,PTPRO,NTM,KCNJ10,TMCC2,ARNT2,KCNN3,TMEM255A,DNM2,ATG16L1,BEND5,RGS10,TTLL7,RLBP1,SH3GLB1,GPR61,VWA5A,EPB41L1,EPB41L2,RASGRP2" Pubmed 19208628 The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. Pubmed 7.16E-10 5.14E-05 8.71E-07 1.03E-05 10 28 "EPS8,LRRC7,SHANK2,ARHGEF7,CAMK2A,GRIA1,GRIN1,CTNND1,CTNND2,ABI1" Pubmed 10470851 Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 7.71E-10 5.53E-05 9.22E-07 1.09E-05 17 104 "ADCY2,KIAA1109,PPM1E,NLGN1,SLC8A2,SHANK2,SORCS3,IGSF9B,USP33,SON,WDTC1,MYT1L,RAP1GAP2,KAZN,CAMSAP2,NSD2,ARHGEF4" Pubmed 24948802 Stage-specific regulation of oligodendrocyte development by Wnt/?-catenin signaling. Pubmed 1.47E-09 1.05E-04 1.73E-06 2.03E-05 8 16 "MBP,FABP7,SOX10,GFAP,TCF7L2,PTCH1,OLIG1,OLIG2" Pubmed 20610746 NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. Pubmed 1.57E-09 1.13E-04 1.78E-06 2.10E-05 10 30 "ASCL1,SOX10,GFAP,NFIA,GRIK4,PAX6,HES5,PROX1,OLIG1,OLIG2" Pubmed 26928066 Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Pubmed 1.57E-09 1.13E-04 1.78E-06 2.10E-05 10 30 "MAG,ERMN,APC,SOX10,GFAP,MYRF,TCF7L2,HES5,OLIG1,OLIG2" Pubmed 16537572 Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Pubmed 1.59E-09 1.14E-04 1.78E-06 2.10E-05 23 203 "FABP7,CSPG5,DLL3,SCN3B,NCAM1,NCDN,NELL1,ADAMTS8,TLL2,PAX6,HAPLN2,SEMA5B,COL9A2,PACSIN1,MED1,PNKD,VCAN,NCAN,PRKCG,ZBTB16,PTHLH,CRTAC1,BAALC" Pubmed 15840001 Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Pubmed 1.69E-09 1.21E-04 1.87E-06 2.20E-05 38 504 "EPS8,RBM10,LGR4,ARID1A,PKP4,DGKD,ZCCHC17,TACC2,SORBS1,ERBIN,KAZN,CAMTA1,NODAL,WWC1,TCF12,ZFP91,CD81,CADM1,TJP2,FTO,MEAF6,CHD1L,TENM4,OSBPL3,RBPJ,CTNND1,PUM1,WBP1L,DNAJC6,PMEPA1,RABGAP1L,CAB39L,RALGDS,JMJD1C,RNF220,SIDT2,EPB41L1,EPB41L2" Pubmed 20201926 Human variation in alcohol response is influenced by variation in neuronal signaling genes. Pubmed 1.88E-09 1.35E-04 2.02E-06 2.38E-05 21 171 "ACTN2,DSCAML1,SORBS1,NLGN1,GAD2,ZNF638,GNAS,CACNB2,GRIK4,ADAMTS8,CCKBR,PDE4B,CHRM1,NRXN1,FEZ2,VCAN,PTPRD,PTPRE,PTPRZ1,KCNH1,PCDH15" Pubmed 10512203 Exchangeable gene trap using the Cre/mutated lox system. Pubmed 1.89E-09 1.36E-04 2.02E-06 2.38E-05 38 506 "EPS8,RBM10,LGR4,ARID1A,PKP4,DGKD,ZCCHC17,TACC2,SORBS1,ERBIN,KAZN,CAMTA1,NODAL,WWC1,TCF12,ZFP91,CD81,CADM1,TJP2,FTO,MEAF6,CHD1L,TENM4,OSBPL3,RBPJ,CTNND1,PUM1,WBP1L,DNAJC6,PMEPA1,RABGAP1L,CAB39L,RALGDS,JMJD1C,RNF220,SIDT2,EPB41L1,EPB41L2" Pubmed 27806288 Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Pubmed 2.26E-09 1.62E-04 2.39E-06 2.81E-05 10 31 "APC,SLIT1,SOX10,ALDH1L1,GFAP,NFIA,NKX2-2,ZEB1,PAX6,OLIG2" Pubmed 19240061 Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Pubmed 3.13E-09 2.25E-04 3.26E-06 3.83E-05 26 265 "EYA1,CSMD2,SLITRK1,BBOX1,SOX6,NTNG1,DNAH17,AJAP1,ACSBG1,MMD2,GUCY1A2,IGSF21,TNS1,PDE1C,PDE4B,TMEFF2,RBPJ,DOCK7,CTNND2,ZNF385B,CA10,PTHLH,MAGI2,PTPRD,PCDH15,DSCAM" Pubmed 20436479 A genomic atlas of mouse hypothalamic development. Pubmed 3.88E-09 2.79E-04 3.98E-06 4.68E-05 22 195 "ADGRV1,SEMA6A,FOXG1,YPEL4,TMEM151A,DKK3,GAD2,NKX6-2,GFRA1,NKX2-2,ROBO3,GPM6B,NCAN,IGSF1,HES5,PROX1,KIAA0513,KCNA2,SLC17A6,RASGRF1,OLIG2,SEZ6" Pubmed 15629701 Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Pubmed 3.94E-09 2.83E-04 3.98E-06 4.68E-05 7 12 "MBP,ASCL1,SOX10,NKX6-2,OLIG1,DBX2,OLIG2" Pubmed 18448566 Neurogenin 2 has an essential role in development of the dentate gyrus. Pubmed 4.78E-09 3.43E-04 4.70E-06 5.52E-05 8 18 "ASCL1,GFAP,NEUROD1,GRIK2,PROX1,ELAVL3,ELAVL4,OLIG2" Pubmed 26701169 "Prss56, a novel marker of adult neurogenesis in the mouse brain." Pubmed 4.78E-09 3.43E-04 4.70E-06 5.52E-05 8 18 "FABP7,APC,SOX10,GFAP,NEUROD1,PROX1,ELAVL3,ELAVL4" Pubmed 23382691 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. Pubmed 5.68E-09 4.07E-04 5.51E-06 6.47E-05 22 199 "SYT9,GPR158,LRRTM4,SORBS1,LRRC4C,SLC8A3,CADPS,SLIT1,NRG3,DNER,GFRA1,GPM6A,CACNA1E,GRM3,MAGI1,VAV2,CNTN1,PLD5,ELMO1,PEX5,DPP6,EPB41L2" Pubmed 21382552 Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch. Pubmed 6.05E-09 4.34E-04 5.71E-06 6.72E-05 6 8 "ASCL1,SOX10,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 26345464 Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain. Pubmed 6.05E-09 4.34E-04 5.71E-06 6.72E-05 6 8 "MBP,SOX6,APC,SOX5,SOX10,OLIG2" Pubmed 24448406 The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Pubmed 7.14E-09 5.13E-04 6.66E-06 7.83E-05 9 26 "NLGN1,KIF21B,CADM3,PTBP2,CAMK2A,GRIA2,MAGI1,KCNQ2,DNM2" Pubmed 25382142 Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle. Pubmed 8.07E-09 5.80E-04 7.31E-06 8.59E-05 8 19 "MBP,AQP4,GFAP,MLC1,TJP1,HEPACAM,KCNJ10,OLIG2" Pubmed 2137249 Diabetogenic response to streptozotocin varies among obese yellow and among lean agouti (BALB/c x VY)F1 hybrid mice. Pubmed 8.07E-09 5.80E-04 7.31E-06 8.59E-05 8 19 "FABP7,APC,SOX10,GFAP,NEUROD1,PROX1,ELAVL3,ELAVL4" Pubmed 26637354 Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. Pubmed 8.35E-09 5.99E-04 7.31E-06 8.59E-05 7 13 "MAG,MBP,SOX10,GFAP,NKX2-2,OLIG1,OLIG2" Pubmed 15601927 CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure. Pubmed 8.35E-09 5.99E-04 7.31E-06 8.59E-05 7 13 "MAG,MBP,NKX6-2,NFASC,CNTN2,CNTN1,KCNA2" Pubmed 27923395 Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain. Pubmed 8.35E-09 5.99E-04 7.31E-06 8.59E-05 7 13 "ASCL1,TAGLN3,NHLH1,CNTN2,PAX6,CHGA,RBPJ" Pubmed 25798587 Ion channel expression in the developing enteric nervous system. Pubmed 8.56E-09 6.15E-04 7.32E-06 8.61E-05 10 35 "ANK3,CACNA1A,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNN3,KCNQ2" Pubmed 21862448 Gene expression analysis of the embryonic subplate. Pubmed 8.56E-09 6.15E-04 7.32E-06 8.61E-05 10 35 "CSMD3,SLC8A2,SLIT1,NEUROD1,UNC5D,CDH10,KCNT2,LRRTM3,RASGRF1,RCAN2" Pubmed 19386638 Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Pubmed 9.51E-09 6.83E-04 8.03E-06 9.44E-05 17 122 "RXRG,FOXG1,ASCL1,SOX1,NKX6-2,SALL3,NKX2-2,GUCY1A1,PAX6,CDH8,NXPH1,POU3F2,POU3F4,HES5,PROX1,LMO1,OLIG2" Pubmed 22745667 Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. Pubmed 1.00E-08 7.21E-04 8.39E-06 9.86E-05 12 56 "SNX30,FGR,AMPH,ITSN1,SORBS1,FYN,TJP1,PACSIN1,ARHGEF4,DLG2,DLG3,ABI2" Pubmed 27611684 mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium. Pubmed 1.05E-08 7.52E-04 8.65E-06 1.02E-04 9 27 "DPF1,ACTL6B,FOXG1,ASCL1,NCAM1,NEUROD1,PAX6,ELAVL3,ELAVL4" Pubmed 15368895 Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.07E-08 7.68E-04 8.73E-06 1.03E-04 35 471 "NDRG2,SLITRK1,WAC,KIAA1109,DISP3,NTNG1,MAGI3,GAS7,GPAM,DGKD,CLSTN1,SLC7A14,RUFY2,DNAH17,PALLD,SCN3B,BCL2L2,RGL1,NFIA,GLS,ASTN2,KAZN,DDHD2,PRUNE2,BRSK2,NLGN3,PNKD,OSBPL3,ATRNL1,SYTL2,CEP170,TMCC2,RAP1GAP,JMJD1C,SH3GLB1" Pubmed 25921289 Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Pubmed 1.19E-08 8.52E-04 9.58E-06 1.13E-04 89 1922 "ACLY,ADAR,TRIM46,SFPQ,CDC42BPA,ANK2,PPFIA1,PPM1E,API5,SHTN1,RPH3A,URGCP,MADD,CCDC88A,MTR,ATP1A3,EIF4G3,PALLD,ZSWIM8,EMC1,GART,NASP,NCAM1,CLASP2,PHLDB1,GANAB,ARHGEF7,SYT4,GNAS,CAMSAP2,TCF12,NRDC,NUDT21,EML4,DDR2,NUMA1,INA,TJP1,AIFM1,CDK11B,PC,RBFOX2,TPM3,TPM4,PDE4B,ACOT7,HMGB1,CHGA,HNRNPK,UBTF,FADS2,VAV2,MICAL1,CHD1L,MED1,SF1,CRMP1,PRKACB,DOCK7,CTNND1,PUM1,PROX1,DPYSL5,TUBB2B,PSMD13,ITGAV,ELMO1,HP1BP3,CEP170,CSDE1,ZC3H11A,SV2A,SNX27,KIF2A,DNM2,GNE,RTN4,L1CAM,ZYG11B,NUP214,RET,ATL1,VANGL2,RBM12,ABI2,ELAVL3,ELAVL4,PRRT4,EPB41" Pubmed 27880917 Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Pubmed 1.38E-08 9.88E-04 1.10E-05 1.29E-04 58 1048 "EYA1,ARID1A,CDC42BPA,ANK3,PPFIA1,PKP4,PPM1E,CACHD1,PAAF1,MADD,ARHGAP5,CCDC88A,CSPG5,EMC1,CLASP2,ERBIN,GANAB,ZNF638,BTRC,PSD3,PTPN5,FBXL16,TJP1,AIFM1,PC,TNS1,TPD52,HMGB1,DUSP26,CADM1,ZFYVE9,UBTF,FTO,PMS2,NSD2,ACBD5,PTPA,PPP2R5C,PPP3CB,FMN2,CTNND1,MAPK8,PUM1,NOS1AP,PSMD13,OCIAD1,PTPRD,SMG7,PTPRE,PTPRZ1,KCNMA1,SNX27,GOPC,DTNA,SLC6A15,ZYG11B,ABI2,EPB41L1" Pubmed 29513653 Developmental diversification of cortical inhibitory interneurons. Pubmed 1.58E-08 1.14E-03 1.25E-05 1.47E-04 14 83 "TTYH1,ASCL1,GAD2,SALL3,NPAS3,NCAM1,NFIA,PAX6,POU3F4,HES5,PROX1,PTPRZ1,LMO1,OLIG2" Pubmed 9051806 Expression of glutamate receptor subunit genes during development of the mouse retina. Pubmed 1.78E-08 1.28E-03 1.39E-05 1.63E-04 6 9 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4" Pubmed 25053427 Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Pubmed 1.88E-08 1.35E-03 1.45E-05 1.71E-04 12 59 "FGF14,ERICH3,CDC42BPA,SCG3,SNAP25,MYT1L,NEUROD1,NHLH1,NKX2-2,CELF3,PAX6,CHGA" Pubmed 15328020 A screen for downstream effectors of Neurogenin2 in the embryonic neocortex. Pubmed 1.96E-08 1.41E-03 1.50E-05 1.76E-04 11 48 "NLGN1,ARHGAP5,UNC5D,GPM6B,PTBP2,GRIK2,PCDH9,NEGR1,SRGAP3,L1CAM,ELAVL4" Pubmed 16330018 Brg1 is required for murine neural stem cell maintenance and gliogenesis. Pubmed 2.08E-08 1.49E-03 1.56E-05 1.83E-04 8 21 "MBP,SOX1,GFAP,NKX2-2,PAX6,ELAVL3,ELAVL4,OLIG2" Pubmed 22726835 Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Pubmed 2.08E-08 1.49E-03 1.56E-05 1.83E-04 8 21 "FOXG1,NEUROD1,NHLH1,UNC5D,CDH8,CDH10,SLC17A6,DSCAM" Pubmed 15939374 eXPRESSION: an in silico tool to predict patterns of gene expression. Pubmed 2.99E-08 2.15E-03 2.15E-05 2.53E-04 9 30 "DGKD,B3GAT1,MYT1L,CADM3,NAP1L2,SEZ6L,PCSK2,OLIG1,OLIG2" Pubmed 9481670 Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+. Pubmed 3.00E-08 2.15E-03 2.15E-05 2.53E-04 7 15 "ACTN2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRIN1" Pubmed 18227507 Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Pubmed 3.00E-08 2.15E-03 2.15E-05 2.53E-04 7 15 "NLGN4X,NLGN1,SNAP25,VAMP1,GRIN1,NLGN3,SLC17A6" Pubmed 27213272 The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination. Pubmed 3.00E-08 2.15E-03 2.15E-05 2.53E-04 7 15 "MAG,MBP,APC,GFAP,NKX2-2,OLIG1,OLIG2" Pubmed 27889896 Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice. Pubmed 3.35E-08 2.40E-03 2.38E-05 2.80E-04 15 102 "NDRG2,PPFIA1,SPHKAP,PHLDB1,KAZN,GRIA2,HEPACAM,NRXN1,NOMO2,PRKCG,CTNND2,KCNJ10,DTNA,ATL1,VWA5A" Pubmed 28489004 Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Pubmed 4.10E-08 2.94E-03 2.87E-05 3.38E-04 12 63 "TTYH1,FABP7,SLC1A2,ATP1A2,ALDH1L1,GFAP,ACSBG1,GPM6B,PAX6,NKAIN4,TUBB2B,PTPRZ1" Pubmed 25179941 Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Pubmed 4.12E-08 2.96E-03 2.87E-05 3.38E-04 9 31 "RXRG,SLC6A9,ASCL1,SOX1,GAD2,GFAP,NKX2-2,PAX6,OLIG2" Pubmed 26525805 Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. Pubmed 4.35E-08 3.12E-03 3.00E-05 3.53E-04 6 10 "MBP,SOX6,SOX5,SOX10,MYRF,OLIG2" Pubmed 11076863 DNA cloning using in vitro site-specific recombination. Pubmed 4.66E-08 3.34E-03 3.19E-05 3.75E-04 47 794 "RBM10,KCNIP2,NDRG2,TOMM40L,HPCAL4,SOX6,SGIP1,APC,GPAM,SORBS1,CSPG5,KBTBD12,SNAP25,PHYHIPL,SCN3B,MYBPC1,FXYD6,SEPT3,C1QC,GPM6B,TCF12,NUDT21,TMEM9,TLL2,JAM2,OPALIN,TJP2,VAV2,C11orf49,PACSIN1,PNKD,NCAN,PRKACB,IGSF1,CTNND2,NOS1AP,RGMA,CSDE1,SV2A,CCDC3,ARNT2,RAB5B,FAM57B,RTN4,SSPN,YY1AP1,PLEKHO1" Pubmed 21238928 Rheb1 is required for mTORC1 and myelination in postnatal brain development. Pubmed 4.80E-08 3.44E-03 3.25E-05 3.82E-04 8 23 "MAG,MAPT,MBP,MOBP,MOG,APC,GFAP,OLIG2" Pubmed 22365546 Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Pubmed 5.22E-08 3.74E-03 3.44E-05 4.04E-04 7 16 "MBP,APC,SOX10,GFAP,MYRF,OLIG1,OLIG2" Pubmed 19258013 Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Pubmed 5.22E-08 3.74E-03 3.44E-05 4.04E-04 7 16 "SLIT1,GFAP,NKX2-2,PAX6,PTCH1,DBX2,OLIG2" Pubmed 20554876 MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord. Pubmed 5.22E-08 3.74E-03 3.44E-05 4.04E-04 7 16 "SLIT1,SOX10,GFAP,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 22632720 High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Pubmed 7.04E-08 5.05E-03 4.53E-05 5.32E-04 8 24 "LRRTM4,VWC2,GRIA1,GRIA2,GRIA4,CPT1C,OLFM3,DLG3" Pubmed 19088086 Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. Pubmed 7.04E-08 5.05E-03 4.53E-05 5.32E-04 8 24 "ASCL1,GAD2,NKX2-2,PAX6,SLC17A6,ELAVL3,ELAVL4,OLIG2" Pubmed 16987237 Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. Pubmed 7.06E-08 5.07E-03 4.53E-05 5.32E-04 12 66 "ACHE,GAD2,CNTN2,CACNA1A,GRIA1,GRIK2,GRIN1,PCSK2,PDYN,NRXN1,NRXN2,DSCAM" Pubmed 22723691 Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord. Pubmed 8.16E-08 5.85E-03 5.18E-05 6.09E-04 13 80 "ADCYAP1R1,GABBR1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,NTSR2,TLX1" Pubmed 23332759 Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Pubmed 8.68E-08 6.23E-03 5.42E-05 6.37E-04 7 17 "MBP,APC,SOX10,GFAP,MYRF,OLIG1,OLIG2" Pubmed 17678855 Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Pubmed 8.68E-08 6.23E-03 5.42E-05 6.37E-04 7 17 "MBP,ASCL1,SOX10,NKX2-2,PTCH1,OLIG1,OLIG2" Pubmed 14534257 "The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion." Pubmed 9.37E-08 6.72E-03 5.70E-05 6.70E-04 6 11 "MAG,MBP,MOG,OLIG1,RTN4,OLIG2" Pubmed 23637331 The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors. Pubmed 9.37E-08 6.72E-03 5.70E-05 6.70E-04 6 11 "MBP,FOXG1,ASCL1,SOX10,PAX6,OLIG2" Pubmed 22500632 Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Pubmed 9.37E-08 6.72E-03 5.70E-05 6.70E-04 6 11 "NDRG2,ZCCHC24,NFIA,MMD2,ARHGEF4,FGFBP3" Pubmed 23359859 NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Pubmed 1.01E-07 7.27E-03 6.11E-05 7.18E-04 8 25 "ACTL6B,SLC1A6,GABBR1,HNRNPK,DLG3,RASGRF1,SLC4A10,RASGRP2" Pubmed 11471062 High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Pubmed 1.08E-07 7.74E-03 6.45E-05 7.58E-04 11 56 "MAPT,ACLY,SNAP25,GFAP,PCSK2,PDYN,MED1,SIRPA,MED24,KCNJ4,RBM12" Pubmed 16944949 Identification of 14-3-3epsilon substrates from embryonic murine brain. Pubmed 1.36E-07 9.76E-03 8.07E-05 9.49E-04 16 129 "ACLY,ATAT1,SFPQ,CCDC88A,KIF21B,DCLK2,BRSK2,INA,DCLK1,DLGAP3,DOCK7,CTNND1,RIMS3,CEP170,SRGAP3,EEF1A2" Pubmed 15342556 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Pubmed 1.38E-07 9.91E-03 8.11E-05 9.54E-04 60 1177 "PAQR6,ATAT1,MDM4,RYR1,PLA2G6,ASRGL1,ANK3,APC,GAS7,MT3,SLN,RCOR3,SCN3B,MYBPC1,NEK6,KIF1B,BCL2L2,ERBIN,RGL1,ZNF638,PSRC1,GOLGB1,ATF7,CACNA1E,CACNB2,GRIA2,CYB561A3,OLR1,MFSD2A,ZFP91,ZNF384,BEST3,NLGN3,GDAP1L1,UBTF,CPT1C,OPALIN,SLC25A27,PMS2,ACBD5,MED1,CRLS1,NKAIN4,VCAN,CTNND1,KLK6,ANKS1B,DNAJC6,CEP170,CSDE1,SV2A,PLEKHB2,RAP1GAP,GNE,BSDC1,SEC61A2,SSPN,LMO1,BSCL2,RCAN2" Pubmed 11955448 Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Pubmed 1.39E-07 9.97E-03 8.11E-05 9.54E-04 7 18 "MBP,SOX10,GFAP,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 27789623 Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Pubmed 1.43E-07 1.03E-02 8.26E-05 9.72E-04 8 26 "ASCL1,SOX10,NKX6-2,NKX2-2,SLC17A6,ELAVL3,ELAVL4,OLIG2" Pubmed 16303743 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Pubmed 1.44E-07 1.03E-02 8.26E-05 9.72E-04 31 430 "RTN3,LDLRAD3,WLS,TUBB4A,DRAXIN,SEMA6A,PI16,SCG3,DLL3,EMC1,ADAM15,GPR19,CYB561A3,SPX,TMEM25,LEFTY2,MFSD2A,TMEM9,PAX6,IGSF21,ADGRG1,MS4A7,TMEFF2,NLGN3,CADM1,FADS2,SYTL2,RGMA,SV2A,SIDT2,FGFBP3" Pubmed 15123239 An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies. Pubmed 1.48E-07 1.06E-02 8.42E-05 9.91E-04 13 84 "ACTN2,APC,SLC1A7,ATP2B2,ADGRB2,ERBIN,ARHGEF7,PRLHR,GUCY1A2,KCNA4,KCNJ4,KCNJ10,LMO1" Pubmed 12421765 Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. Pubmed 1.52E-07 1.09E-02 8.57E-05 1.01E-03 16 130 "DSCAML1,SEMA6A,MAGI3,SORBS1,CACHD1,SHTN1,CLSTN1,MADD,CADPS,WDTC1,NRXN1,NRXN2,PLXNB3,IGSF1,MAGI2,RBM12" Pubmed 19274049 "A census of human transcription factors: function, expression and evolution." Pubmed 1.62E-07 1.16E-02 9.07E-05 1.07E-03 50 908 "RXRG,FOXG1,SOX6,FOXM1,MIER1,PKNOX2,DACH2,ASCL1,RCOR3,SOX1,MYT1L,SOX5,SOX10,NKX6-2,NPAS3,RCOR2,NEUROD1,NFIA,NHLH1,NKX2-2,CAMTA1,MYRF,TBX15,ATF7,TCF7L2,ZEB1,TCF12,AKNA,MAEL,PAX6,ZNF384,TLX1,UBTF,PRRX1,NSD2,POU3F2,POU3F4,RBPJ,HES5,PROX1,GON4L,PRDM2,ZC3H11A,ARNT2,OLIG1,DBX2,RFX4,RFX5,EN2,OLIG2" Pubmed 9651535 Glutamate receptors: brain function and signal transduction. Pubmed 1.85E-07 1.33E-02 1.00E-04 1.18E-03 5 7 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3" Pubmed 9016303 Glutamate receptors in cortical plasticity: molecular and cellular biology. Pubmed 1.85E-07 1.33E-02 1.00E-04 1.18E-03 5 7 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3" Pubmed 1310861 Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate. Pubmed 1.85E-07 1.33E-02 1.00E-04 1.18E-03 5 7 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3" Pubmed 27619418 Pore size matters for potassium channel conductance. Pubmed 1.85E-07 1.33E-02 1.00E-04 1.18E-03 5 7 "KCNA1,KCNA2,KCNA4,KCNA6,KCNMA1" Pubmed 19217427 AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Pubmed 2.15E-07 1.55E-02 1.15E-04 1.35E-03 7 19 "MBP,FABP7,APC,GFAP,PRKAB2,PRKCZ,OLIG2" Pubmed 23903190 GDNF is required for neural colonization of the pancreas. Pubmed 2.15E-07 1.55E-02 1.15E-04 1.35E-03 7 19 "SOX10,GFAP,GFRA1,NKX2-2,RET,ELAVL3,ELAVL4" Pubmed 17916349 A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Pubmed 2.15E-07 1.55E-02 1.15E-04 1.35E-03 7 19 "ACHE,GRIK4,TJP1,PAX6,POU3F2,HES5,PROX1" Pubmed 21192082 Dynamic spatiotemporal gene expression in embryonic mouse thalamus. Pubmed 2.23E-07 1.60E-02 1.18E-04 1.38E-03 9 37 "FABP7,ASCL1,GFRA1,NKX2-2,GRIA1,GRM3,PROX1,PTCH1,SLC17A6" Pubmed 17043677 Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Pubmed 2.31E-07 1.66E-02 1.21E-04 1.42E-03 17 151 "WAC,ANK2,PPM1E,SYBU,ZNF365,CCDC88A,SMARCE1,MYT1L,TNIK,WWC1,PDE4B,CCSER2,CCDC136,KIAA0408,CEP170,SRGAP3,ABI2" Pubmed 20195357 A comprehensive resource of interacting protein regions for refining human transcription factor networks. Pubmed 2.77E-07 1.99E-02 1.44E-04 1.69E-03 19 189 "TUBB4A,LINC00461,KIAA1109,ANK2,ANK3,ANXA7,CLSTN1,GABBR1,GNAS,CAMSAP2,ATF7,HMGB1,UBTF,CABP1,FEZ1,KIAA0408,SYTL2,OCIAD1,GOPC" Pubmed 10718198 Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. Pubmed 2.80E-07 2.01E-02 1.44E-04 1.70E-03 17 153 "SCN3A,KIAA1109,DISP3,LRRC7,SEMA6A,UNC79,SORBS1,RCOR3,NFIA,PCDH11X,SYT4,PACSIN1,TENM4,CHD5,NAV2,RALGDS,JMJD1C" Pubmed 22802532 Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Pubmed 2.86E-07 2.05E-02 1.46E-04 1.72E-03 9 38 "ANK3,SPHKAP,SNAP25,ATM,PTBP2,CAMK2G,PAX6,TPM3,PPP3CB" Pubmed 24722188 Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Pubmed 3.21E-07 2.30E-02 1.63E-04 1.91E-03 29 400 "ABAT,GALNT13,WAC,PPFIA1,NTNG1,NPAS3,FAM168A,TCF12,C1orf94,PCDH9,CDH10,PDE4B,NLGN3,CADM1,CCDC136,NECAB2,IFFO1,CHD1L,CRMP1,PRKAB2,CMTM5,RIMS3,BLOC1S6,ZC3H11A,ARNT2,DLG2,PYGM,GOPC,BEND5" Pubmed 20417196 Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Pubmed 3.24E-07 2.33E-02 1.63E-04 1.91E-03 7 20 "ASCL1,NKX2-2,PAX6,HES5,SLC17A6,ELAVL3,ELAVL4" Pubmed 27469598 Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Pubmed 3.24E-07 2.33E-02 1.63E-04 1.91E-03 7 20 "FABP7,APC,GFAP,PAX6,POU3F2,OLIG1,OLIG2" Pubmed 25680202 Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells. Pubmed 3.33E-07 2.39E-02 1.65E-04 1.94E-03 6 13 "MBP,SOX10,NKX2-2,MYRF,OLIG1,OLIG2" Pubmed 16880397 From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Pubmed 3.33E-07 2.39E-02 1.65E-04 1.94E-03 6 13 "SLC1A2,GRIA1,GRIA2,GRIA4,GRIN1,L1CAM" Pubmed 23431145 The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Pubmed 3.39E-07 2.43E-02 1.67E-04 1.96E-03 13 90 "BCAN,DNER,ALDH1L1,PAX6,CDH8,CDH10,FAT3,MICAL2,LRRTM3,PTPRO,NAV2,LMO1,FGFBP3" Pubmed 10574461 Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. Pubmed 3.55E-07 2.55E-02 1.73E-04 2.04E-03 12 76 "DSCAML1,HHATL,PNMA8B,ERMN,GPR158,CADPS,SCN3B,ZMYND8,CCSER2,PNKD,SPIRE1,SRGAP3" Pubmed 16186258 Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. Pubmed 3.68E-07 2.64E-02 1.76E-04 2.07E-03 8 29 "PPFIA1,NLGN1,SNAP25,GRIA2,GRIA4,NLGN3,NRXN1,RAB5B" Pubmed 25556712 Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Pubmed 3.68E-07 2.64E-02 1.76E-04 2.07E-03 8 29 "RXRG,ASCL1,GFAP,NEUROD1,PAX6,HES5,ELAVL3,ELAVL4" Pubmed 17500595 Huntingtin interacting proteins are genetic modifiers of neurodegeneration. Pubmed 3.70E-07 2.66E-02 1.76E-04 2.07E-03 18 174 "WAC,MOG,SORBS1,SLC1A2,ASPH,SNAP25,GFAP,GPM6A,OPCML,NEGR1,CNTN1,PACSIN1,FEZ1,SIRPA,SRGAP3,NTM,EPB41,EPB41L1" Pubmed 18940311 Recurrent CNVs disrupt three candidate genes in schizophrenia patients. Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "MYT1L,ASTN2,NRXN1,CTNND2" Pubmed 19150847 "Draxin, a repulsive guidance protein for spinal cord and forebrain commissures." Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "DRAXIN,GFAP,CNTN2,L1CAM" Pubmed 15707673 "Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system." Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "NCAM1,CNTN2,CADM1,L1CAM" Pubmed 24243019 Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "MAPT,ASCL1,MYT1L,POU3F2" Pubmed 15485773 "Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and biochemical study." Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "MAG,MBP,FYN,NCAM1" Pubmed 20573900 "Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration." Pubmed 3.82E-07 2.74E-02 1.76E-04 2.07E-03 4 4 "NLGN1,ASTN1,GFAP,ASTN2" Pubmed 28705898 Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Pubmed 4.16E-07 2.99E-02 1.90E-04 2.24E-03 15 123 "SEMA6A,CACHD1,FXYD6,NASP,GFRA1,PSRC1,B4GALNT4,MFSD2A,ACOT7,SERPINE2,CADM1,CTNND2,ARNT2,NKAIN1,RET" Pubmed 24194600 "The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data." Pubmed 4.48E-07 3.22E-02 1.99E-04 2.34E-03 54 1050 "DPF1,MAG,ADGRV1,ADAR,SLITRK1,ADCYAP1R1,GPR158,BBOX1,ELMOD1,HPCAL4,SGIP1,PKP4,SLC8A3,ATP1A3,GAD2,KIF1B,STARD10,ADGRB2,ALDH1L1,AJAP1,MLC1,RHBDL3,POPDC3,TMEM136,WSCD1,GPR17,GPR19,TMEM151B,GRM3,ATP13A2,PTPN5,USP2,FBXL16,P2RX7,PC,PADI2,CDH10,CHRNB2,JAM2,NRXN1,COL9A2,SPATA6,CP,PRKAB2,NRSN1,RIMS3,KCNJ9,KCNJ11,SNX27,CAB39L,PARP11,FGFBP3,LPAR6,TMEM100" Pubmed 22705452 PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Pubmed 4.76E-07 3.42E-02 1.99E-04 2.34E-03 7 21 "GFAP,PTBP2,TJP1,PAX6,POU3F2,PRKCZ,OLIG2" Pubmed 27076429 Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System. Pubmed 4.76E-07 3.42E-02 1.99E-04 2.34E-03 7 21 "FABP7,ASCL1,SOX10,NEUROD1,RET,ELAVL3,ELAVL4" Pubmed 26494785 FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Pubmed 4.76E-07 3.42E-02 1.99E-04 2.34E-03 7 21 "CNTNAP3,RYR1,SPHKAP,DNER,FBXL16,ELAVL4,RASGRP2" Pubmed 22998872 MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Pubmed 4.76E-07 3.42E-02 1.99E-04 2.34E-03 7 21 "MBP,FABP7,GFAP,ACSBG1,PAX6,L1CAM,OLIG2" Pubmed 22412988 Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "APC,ASCL1,CNTN2,PAX6,L1CAM" Pubmed 11239431 Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "FABP7,ASCL1,GFAP,NEUROD1,HES5" Pubmed 11526078 Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "MBP,GFAP,NKX2-2,OLIG1,OLIG2" Pubmed 16696976 Two mechanistically distinct forms of endocytosis in adrenal chromaffin cells: Differential effects of SH3 domains and amphiphysin antagonism. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "AMPH,ITSN1,SH3GL2,DNM2,SH3GLB1" Pubmed 24618891 Genome-wide association study reveals two new risk loci for bipolar disorder. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "ADCY2,ANK3,POU3F2,TENM4,NCAN" Pubmed 19125103 "Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia." Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "GAD2,GRIA4,GRIK3,GRIK4,GRM3" Pubmed 17131403 "Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development." Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "MAPT,CNTN2,CNTN1,FAT3,L1CAM" Pubmed 9184108 Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "NCAM1,VCAN,NCAN,PTPRZ1,L1CAM" Pubmed 16603319 Expression of discoidin domain receptor 1 during mouse brain development follows the progress of myelination. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "MBP,APC,GFAP,CNDP1,DDR1" Pubmed 18615557 Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "FABP7,CADM3,CADM1,CADM2,SLC17A6" Pubmed 10547923 A QTL for the genetic variance in free-running period and level of locomotor activity between inbred strains of mice. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "RXRG,NHLH1,DDR2,KCNJ10,VANGL2" Pubmed 18287202 Ascl1 is required for oligodendrocyte development in the spinal cord. Pubmed 4.82E-07 3.46E-02 1.99E-04 2.34E-03 5 8 "MAG,MBP,ASCL1,NKX2-2,OLIG2" Pubmed 19838179 Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Pubmed 4.91E-07 3.53E-02 2.01E-04 2.37E-03 8 30 "FABP7,SOX5,GFAP,POU3F2,MAPK8,ELAVL3,ELAVL4,OLIG2" Pubmed 19741146 A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. Pubmed 5.67E-07 4.07E-02 2.31E-04 2.72E-03 13 94 "MBP,FOXM1,SMARCE1,SOX10,GFAP,NFIA,NKX2-2,TCF7L2,TCF12,HES5,OLIG1,RFX4,OLIG2" Pubmed 16407399 Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Pubmed 5.71E-07 4.10E-02 2.32E-04 2.72E-03 6 14 "MBP,GFAP,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 17634366 Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. Pubmed 5.80E-07 4.16E-02 2.34E-04 2.75E-03 17 161 "MAG,MBP,TUBB4A,MOBP,MOG,TAGLN3,SNAP25,ATP1A2,ATP1A3,NFASC,NCAM1,GFAP,INA,CNTN1,PACSIN1,CNRIP1,EEF1A2" Pubmed 16919269 A global genomic transcriptional code associated with CNS-expressed genes. Pubmed 6.13E-07 4.40E-02 2.46E-04 2.89E-03 24 301 "ADCYAP1R1,SORCS1,GRAMD1B,NLGN1,ST8SIA1,ARHGAP5,SORCS3,SOX5,NPAS3,DCLK2,BTRC,TCF12,GRIA2,PAX6,CDH8,NRXN1,FTO,IGSF1,PROX1,PTCH1,KCNA1,PTPRE,SLC4A10,ELAVL4" Pubmed 15215207 Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord. Pubmed 6.83E-07 4.90E-02 2.72E-04 3.20E-03 7 22 "ASCL1,NKX6-2,NKX2-2,PAX6,PTCH1,DBX2,OLIG2" Pubmed 18725516 Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Pubmed 7.27E-07 5.22E-02 2.88E-04 3.39E-03 11 67 "TTYH1,NDRG2,CCDC80,SYBU,NSG2,DLL3,NEUROD1,SDC3,LRP8,SLC17A6,ELAVL4" Pubmed 22991445 Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Pubmed 8.45E-07 6.06E-02 3.31E-04 3.90E-03 8 32 "AQP4,SLC14A1,ALDH1L1,GFAP,KIRREL3,PAX6,POU3F2,CRTAC1" Pubmed 19286674 Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Pubmed 8.45E-07 6.06E-02 3.31E-04 3.90E-03 8 32 "SOX1,NKX2-2,PAX6,POU3F2,HES5,PTCH1,DBX2,OLIG2" Pubmed 16381901 The LIFEdb database in 2006. Pubmed 9.04E-07 6.49E-02 3.48E-04 4.10E-03 41 720 "RBM10,KCNIP2,NDRG2,TOMM40L,HPCAL4,SOX6,SGIP1,GPAM,SORBS1,KBTBD12,SNAP25,PHYHIPL,SCN3B,MYBPC1,FXYD6,SEPT3,C1QC,GPM6B,TCF12,NUDT21,TMEM9,JAM2,OPALIN,TJP2,VAV2,C11orf49,PACSIN1,PNKD,PRKACB,IGSF1,RGMA,CSDE1,SV2A,CCDC3,ARNT2,RAB5B,FAM57B,RTN4,SSPN,YY1AP1,PLEKHO1" Pubmed 15302935 Large-scale characterization of HeLa cell nuclear phosphoproteins. Pubmed 9.11E-07 6.54E-02 3.48E-04 4.10E-03 43 773 "MAPT,ACLY,RBM10,CLIP1,FOXM1,ITSN1,USP16,MIER1,URGCP,ARFGAP1,ASPH,ATM,SON,KIF1B,NASP,ERBIN,NFIA,ZNF638,UNC5D,ZEB1,EML4,NUMA1,RFFL,ZFP91,CDK11B,TPM3,ZMYND8,HNRNPK,ANLN,TJP2,MED1,SF1,PKN2,MAPK8,PRDM2,MED24,ZC3H11A,DNM2,ATN1,NUP214,PHC2,YY1AP1,EPB41L2" Pubmed 24257626 Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "MBP,SOX1,SOX10,GFAP,MYRF,OLIG2" Pubmed 22337526 Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "MAG,MBP,SOX10,GFAP,GJB1,OLIG2" Pubmed 20969845 Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "ASCL1,PAX6,HES5,PTCH1,ELAVL3,ELAVL4" Pubmed 15893981 Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "MBP,FABP7,SOX1,SOX10,NKX2-2,OLIG2" Pubmed 12490199 Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "MBP,SOX10,GFAP,NKX2-2,PAX6,OLIG2" Pubmed 15629702 Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "SOX10,NKX6-2,NKX2-2,OLIG1,DBX2,OLIG2" Pubmed 22956844 Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. Pubmed 9.32E-07 6.69E-02 3.48E-04 4.10E-03 6 15 "FABP7,ASCL1,NCAM1,GFAP,POU3F2,HES5" Pubmed 23223237 The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. Pubmed 9.61E-07 6.90E-02 3.56E-04 4.18E-03 7 23 "ASCL1,SOX1,ALDH1L1,GFAP,NFIA,HES5,OLIG2" Pubmed 22988430 A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Pubmed 9.61E-07 6.90E-02 3.56E-04 4.18E-03 7 23 "ACHE,NDRG2,TACC2,SOX10,KIF1B,RTN4,LMO1" Pubmed 15489336 From ORFeome to biology: a functional genomics pipeline. Pubmed 9.70E-07 6.96E-02 3.57E-04 4.20E-03 41 722 "RBM10,KCNIP2,NDRG2,TOMM40L,HPCAL4,SOX6,SGIP1,GPAM,SORBS1,KBTBD12,SNAP25,PHYHIPL,SCN3B,MYBPC1,FXYD6,SEPT3,C1QC,GPM6B,TCF12,NUDT21,TMEM9,JAM2,OPALIN,TJP2,VAV2,C11orf49,PACSIN1,PNKD,PRKACB,IGSF1,RGMA,CSDE1,SV2A,CCDC3,ARNT2,RAB5B,FAM57B,RTN4,SSPN,YY1AP1,PLEKHO1" Pubmed 29055695 Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Pubmed 1.04E-06 7.46E-02 3.69E-04 4.33E-03 10 56 "SFPQ,NPAS3,TCF12,PTBP2,PAX6,RBFOX2,HNRNPK,MED1,HES5,CSDE1" Pubmed 9278515 Binding of neuroligins to PSD-95. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "NLGN4X,NLGN1,NLGN3,DLG2,DLG3" Pubmed 18551627 Development of satellite glia in mouse sympathetic ganglia: GDNF and GFR alpha 1 are not essential. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "FABP7,SOX10,NCAM1,GFRA1,RET" Pubmed 24292102 Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "GRIA1,GRIA2,GRIA4,GRIN1,CHRM1" Pubmed 11799060 Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "MAG,MBP,SOX10,GFAP,OLIG2" Pubmed 19544586 In vitro and in vivo differentiation of human embryonic stem cells into retina-like organs and comparison with that from mouse pluripotent epiblast stem cells. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "GFAP,PAX6,ELAVL3,ELAVL4,RPE65" Pubmed 25653379 Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "ANK3,BCAN,NFASC,GFAP,KCNA1" Pubmed 11566099 Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "SOX10,NKX2-2,PAX6,OLIG1,OLIG2" Pubmed 18367611 Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "CNTN2,PIK3CD,PRKCZ,PARD6A,L1CAM" Pubmed 10512984 Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "MBP,TUBB4A,APC,NCAM1,GFAP" Pubmed 24449836 Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "MBP,SOX10,NKX2-2,OLIG1,OLIG2" Pubmed 27800545 Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. Pubmed 1.06E-06 7.63E-02 3.69E-04 4.33E-03 5 9 "SYNDIG1,GRIA1,GRIA2,GRIN1,DLG2" Pubmed 27565344 Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Pubmed 1.09E-06 7.83E-02 3.75E-04 4.41E-03 8 33 "CLIP1,CLASP2,DCLK2,EML4,PAX6,KIF2A,ABI1,EPB41L1" Pubmed 25631876 The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon. Pubmed 1.09E-06 7.83E-02 3.75E-04 4.41E-03 8 33 "SEMA6A,SLIT1,NKX6-2,NKX2-2,PAX6,SEMA5B,PTCH1,OLIG2" Pubmed 10997877 Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.31E-06 9.41E-02 4.48E-04 5.27E-03 13 101 "MAGI3,GPAM,CACHD1,LRRC4C,SHTN1,MIER1,SLC7A14,KIAA1614,SFMBT2,SYTL2,GON4L,ARHGEF10L,RAVER2" Pubmed 22365545 A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Pubmed 1.33E-06 9.54E-02 4.52E-04 5.32E-03 9 45 "FABP7,DRAXIN,SLIT1,GFAP,NFIA,CNTN2,PAX6,POU3F2,L1CAM" Pubmed 29229865 Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Pubmed 1.46E-06 1.05E-01 4.90E-04 5.76E-03 6 16 "FOXG1,CCDC88A,NUCB1,TJP1,PRKCZ,VANGL2" Pubmed 18184563 Members of the miRNA-200 family regulate olfactory neurogenesis. Pubmed 1.46E-06 1.05E-01 4.90E-04 5.76E-03 6 16 "FOXG1,ASCL1,NCAM1,NEUROD1,ELAVL3,ELAVL4" Pubmed 19838178 The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Pubmed 1.46E-06 1.05E-01 4.90E-04 5.76E-03 6 16 "MAG,MBP,GFAP,GPR17,OLIG1,OLIG2" Pubmed 27178982 Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. Pubmed 1.80E-06 1.30E-01 5.77E-04 6.78E-03 7 25 "CNTN2,ZEB1,PRKCZ,PTCH1,PARD6A,DLG2,OLIG2" Pubmed 16374509 Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome. Pubmed 1.80E-06 1.30E-01 5.77E-04 6.78E-03 7 25 "SNX30,SH3GL2,SORBS1,FYN,ADAM15,ARHGEF7,SH3GLB1" Pubmed 22334647 Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons. Pubmed 1.80E-06 1.30E-01 5.77E-04 6.78E-03 7 25 "DKK3,GFAP,PAX6,CDH10,L1CAM,ELAVL3,ELAVL4" Pubmed 26514267 Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. Pubmed 1.81E-06 1.30E-01 5.77E-04 6.78E-03 24 320 "TUBB4A,DISP3,TRIM46,USP28,ASCL1,SLIT1,SNAP25,ATP1A3,MYH7,NASP,GFAP,GNAS,DDHD2,GPM6B,COL9A2,CRMP1,PRKCG,PRKCZ,CTNND1,MAPK10,ECE2,STMN4,ZC3H11A,PTPRD" Pubmed 17722031 Differential expression of phosphacan/RPTPbeta isoforms in the developing mouse visual system. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "CNTN2,CNTN1,PTPRZ1,L1CAM" Pubmed 19855010 Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "MAG,APC,OLIG1,OLIG2" Pubmed 8288598 "Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies." Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "GRIA1,GRIA2,GRIK2,GRIK4" Pubmed 11807022 A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "NCAM1,CNTN2,CNTN1,L1CAM" Pubmed 9466455 Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "GRIA1,GRIA4,GRIK2,GRIK3" Pubmed 12827191 Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "CACNA1A,CACNA1E,NRXN1,NRXN2" Pubmed 9482932 "Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM." Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "NCAM1,GRIA1,GRIA2,GRIA4" Pubmed 9507007 "High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule." Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "TNR,HMGB1,NCAN,PTPRZ1" Pubmed 15620359 Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Pubmed 1.82E-06 1.31E-01 5.77E-04 6.78E-03 4 5 "NLGN4X,NLGN1,NLGN3,NRXN1" Pubmed 16189514 Towards a proteome-scale map of the human protein-protein interaction network. Pubmed 1.91E-06 1.37E-01 6.02E-04 7.07E-03 70 1573 "EPS8,RBM10,RTN3,RTN1,RXRG,WAC,AGT,ELMOD1,HPCAL4,PPFIA1,DOCK10,ZCCHC17,RCOR3,SNAP25,PHYHIPL,NEK6,ADAM15,NASP,LMO3,NDUFA5,GFAP,ZNF638,SYT4,BTRC,PRUNE2,NEU4,PTBP2,NUDT21,USP2,CDC42,C1orf94,RBFOX2,TPM3,PRMT8,HNRNPK,SLC22A6,C11orf49,MEAF6,NECAB2,PACSIN1,IFFO1,PNKD,SF1,PRKCZ,KIAA0408,ZBTB16,SIRPA,JAKMIP2,PRTFDC1,BLOC1S6,ZC3H11A,PARD6A,NAV2,PEX5,RAB3IL1,PARP11,GOPC,FAM13C,BEND5,RTN4,PAK5,ABCC9,RGR,PHC2,ABI2,ELAVL3,ELAVL4,YY1AP1,BSCL2,BAALC" Pubmed 22923088 The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Pubmed 2.01E-06 1.44E-01 6.31E-04 7.41E-03 10 60 "FOXG1,ASCL1,FGF17,GRIK4,PAX6,CDH8,HES5,PROX1,L1CAM,ELAVL4" Pubmed 10601035 The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "FOXG1,SLIT1,NKX2-2,PAX6,L1CAM" Pubmed 23862023 Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "FABP7,SOX10,NCAM1,ELAVL3,ELAVL4" Pubmed 20950796 Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "BCAN,B3GAT1,TNR,HAPLN2,NCAN" Pubmed 14602683 Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "MBP,SOX10,NKX2-2,OLIG1,OLIG2" Pubmed 1383027 Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "KCNA1,KCNA2,KCNA4,KCNA6,KCNC1" Pubmed 8901523 Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "SYT9,RPH3A,SYT4,SYT6,NRXN1" Pubmed 19071123 Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions. Pubmed 2.08E-06 1.50E-01 6.33E-04 7.45E-03 5 10 "MAGI3,TJP1,MAGI1,TJP2,GOPC" Pubmed 20110327 Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "FOXG1,NEUROD1,PAX6,PRKCG,RLBP1,OLIG2" Pubmed 16635246 Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "TTYH1,ACTN2,CAMK2A,GRIA1,GRIA2,GRIN1" Pubmed 19439493 "Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1." Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "GFAP,CAMK2A,PAX6,SLC17A6,ELAVL3,ELAVL4" Pubmed 15822905 Phosphoproteomic analysis of synaptosomes from human cerebral cortex. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "MAPT,SLC1A2,NCAM1,GPM6A,PKN2,SV2A" Pubmed 17721516 OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "NTNG1,ASCL1,SLIT1,CNTN2,PAX6,L1CAM" Pubmed 20861386 RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "ATP1A2,ATP1A3,GAD2,FXYD6,GRIA1,GRIN1" Pubmed 19004860 C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "MAPT,NKX2-2,NODAL,LEFTY2,PAX6,PTCH1" Pubmed 25568100 Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "MBP,SOX10,GFAP,NKX2-2,MYRF,OLIG2" Pubmed 23575864 Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "MBP,SOX10,NKX2-2,MYRF,GPR17,OLIG2" Pubmed 19503085 HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Pubmed 2.21E-06 1.59E-01 6.45E-04 7.58E-03 6 17 "MBP,APC,GFAP,TCF7L2,OLIG1,OLIG2" Pubmed 23341629 Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Pubmed 2.27E-06 1.63E-01 6.60E-04 7.76E-03 18 197 "ACHE,SNX30,BCAR3,MSRA,ASPH,ILDR2,GFAP,C1QC,KAZN,GPM6B,FADS2,CP,SDC3,PLPPR4,PYGM,PID1,LMO1,SEZ6" Pubmed 16712791 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Pubmed 2.28E-06 1.64E-01 6.61E-04 7.77E-03 30 465 "SERPINA3,SDE2,RPL38,ZFYVE27,MBP,ACTN2,NDRG2,WAC,SELL,CLSTN1,MT3,ASPH,ATP1A3,DKK3,GJB1,ADHFE1,MLC1,HAP1,PDE1C,HPR,DNAJC12,CHD1L,PRKAB2,PRKCZ,MASP1,WBP1L,ITIH2,RGS10,TMEM100,LRRC23" Pubmed 22939624 Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Pubmed 2.41E-06 1.73E-01 6.93E-04 8.15E-03 26 371 "MDM4,KLHL32,TESK2,FGR,FOXM1,STK32C,FYN,DCLK2,BTRC,DDR1,CAMK2A,CAMK2G,DDR2,TIE1,CDK11B,CAMKV,RGS6,PRKACB,PRKCG,PKN2,PRKCZ,HP1BP3,KCNA6,CAMK1G,RET,RGS7" Pubmed 25056061 Biological insights from 108 schizophrenia-associated genetic loci. Pubmed 2.41E-06 1.73E-01 6.93E-04 8.15E-03 23 303 "GRAMD1B,NLGN4X,YPEL4,IGSF9B,C11orf87,SEPT3,LUZP2,GPM6A,CACNB2,NRGN,GRIA1,GRM3,INA,CA14,RGS6,PLCH2,NCAN,CTNND1,WBP1L,PARD6A,FAM57B,SLC4A10,PLEKHO1" Pubmed 21386911 "Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways." Pubmed 2.54E-06 1.83E-01 7.28E-04 8.56E-03 17 179 "EYA1,CGREF1,ATP1A2,MYBPC1,ALDH1L1,GPM6A,GPM6B,GRIA4,VWCE,OPCML,SLC22A6,NXPH1,SNCAIP,MAGI2,PID1,ELAVL4,TMEM100" Pubmed 23144326 Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Pubmed 3.19E-06 2.29E-01 9.06E-04 1.07E-02 7 27 "EYA1,ASRGL1,JAKMIP3,KAZN,OPCML,P2RX7,NTM" Pubmed 24148613 Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation. Pubmed 3.19E-06 2.29E-01 9.06E-04 1.07E-02 7 27 "ASCL1,NEUROD1,NHLH1,PAX6,HES5,OLIG1,OLIG2" Pubmed 21068056 The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance. Pubmed 3.24E-06 2.33E-01 9.10E-04 1.07E-02 6 18 "SLIT1,NKX2-2,ROBO3,CNTN2,PAX6,OLIG2" Pubmed 28049845 REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Pubmed 3.24E-06 2.33E-01 9.10E-04 1.07E-02 6 18 "ASCL1,GAD2,RCOR2,CHRNB2,PROX1,OLIG2" Pubmed 12874134 Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Pubmed 3.24E-06 2.33E-01 9.10E-04 1.07E-02 6 18 "SOX10,NKX6-2,NKX2-2,PAX6,DBX2,OLIG2" Pubmed 23793025 Genome-wide meta-analysis identifies new susceptibility loci for migraine. Pubmed 3.44E-06 2.47E-01 9.60E-04 1.13E-02 11 78 "EYA1,MRVI1,ADARB2,SORBS1,GFRA1,AJAP1,ASTN2,ATF7,HPSE2,PTPRD,RABGAP1L" Pubmed 25201988 Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Pubmed 3.64E-06 2.61E-01 1.00E-03 1.18E-02 12 94 "MDM4,LINC00461,ITSN1,SNAP25,GART,GPM6A,NRXN1,NEGR1,POU3F2,CEP170,KCNMA1,JMJD1C" Pubmed 25826454 Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Pubmed 3.73E-06 2.68E-01 1.00E-03 1.18E-02 14 128 "DSCAML1,CADM3,CNTN2,LRIT2,VSTM2A,TIE1,JAM2,CADM1,NEGR1,CNTN1,CADM2,NTM,DSCAM,OLIG2" Pubmed 20648636 Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "MBP,APC,SOX10,OLIG1,OLIG2" Pubmed 29500351 Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "MBP,SOX10,NKX2-2,MYRF,OLIG2" Pubmed 20950430 RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "GFAP,PAX6,RBPJ,HES5,PTCH1" Pubmed 22461560 WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "FABP7,APC,SOX1,GFAP,PAX6" Pubmed 26520399 Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "SLIT1,NKX2-2,PAX6,PROX1,L1CAM" Pubmed 9102301 Conservation of the Notch signalling pathway in mammalian neurogenesis. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "ASCL1,NEUROD1,NHLH1,RBPJ,HES5" Pubmed 27452274 Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrn?3 in Cerebellar Granule Neuron progenitors during development. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "ASTN1,ASTN2,PAX6,NLGN3,NRXN1" Pubmed 26156989 Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "FABP7,SOX10,GFRA1,SV2A,RET" Pubmed 22627280 Olig2-dependent developmental fate switch of NG2 cells. Pubmed 3.74E-06 2.68E-01 1.00E-03 1.18E-02 5 11 "MBP,SOX10,ALDH1L1,GFAP,OLIG2" Pubmed 20798045 "Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex." Pubmed 4.00E-06 2.87E-01 1.06E-03 1.25E-02 9 51 "BCAN,SCN3B,B4GALNT1,GFAP,PAX6,POU3F2,CALN1,ST8SIA3,RGS10" Pubmed 21368052 MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. Pubmed 4.00E-06 2.87E-01 1.06E-03 1.25E-02 9 51 "FOXG1,ASCL1,SMARCE1,SOX5,NEUROD1,CNTN2,PAX6,POU3F2,L1CAM" Pubmed 27568567 "Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function." Pubmed 4.17E-06 2.99E-01 1.10E-03 1.30E-02 7 28 "MAG,MOBP,GFAP,GJB1,CCKBR,CHRM4,KCNJ10" Pubmed 16651659 SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Pubmed 4.64E-06 3.33E-01 1.21E-03 1.42E-02 6 19 "SOX1,GFAP,NEUROD1,PAX6,HES5,RLBP1" Pubmed 29285798 Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter. Pubmed 4.64E-06 3.33E-01 1.21E-03 1.42E-02 6 19 "MBP,GFAP,NFIA,NKX2-2,PAX6,OLIG2" Pubmed 17507395 Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia. Pubmed 4.64E-06 3.33E-01 1.21E-03 1.42E-02 6 19 "FABP7,ASCL1,SOX10,RET,ELAVL3,ELAVL4" Pubmed 20685999 A novel transient glutamatergic population migrating from the pallial-subpallial boundary contributes to neocortical development. Pubmed 4.64E-06 3.33E-01 1.21E-03 1.42E-02 6 19 "MAPT,ASCL1,GFAP,PAX6,SLC17A6,OLIG2" Pubmed 23303943 Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions. Pubmed 4.64E-06 3.33E-01 1.21E-03 1.42E-02 6 19 "SOX5,GFAP,CNTN2,CNTN1,POU3F2,L1CAM" Pubmed 16382104 International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pubmed 5.18E-06 3.72E-01 1.27E-03 1.49E-02 8 40 "KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNQ2" Pubmed 9185665 Molecular cloning of Fyn-associated molecules in the mouse central nervous system. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "FYN,SON,RBFOX2,HNRNPK" Pubmed 26516211 NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "APC2,NEUROD1,NHLH1,PCSK2" Pubmed 11746780 Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MAG,MBP,MOG,OMG" Pubmed 19576965 The distribution and characterization of endogenous protein arginine N-methyltransferase 8 in mouse CNS. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MAPT,APC,GFAP,PRMT8" Pubmed 20203209 Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ASCL1,GFAP,RBPJ,HES5" Pubmed 26613292 Multiple Src Homology 3 Binding to the Ubiquitin Ligase Itch Conserved Proline-Rich Region. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ITSN1,SH3GL2,ARHGEF7,PACSIN1" Pubmed 9096138 A hierarchy of Hu RNA binding proteins in developing and adult neurons. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "GFAP,PAH,ELAVL3,ELAVL4" Pubmed 10101124 Defects in thalamocortical axon pathfinding correlate with altered cell domains in Mash-1-deficient mice. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ASCL1,NKX2-2,PAX6,L1CAM" Pubmed 8576240 "Structures, alternative splicing, and neurexin binding of multiple neuroligins." Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "NLGN1,NLGN3,NRXN1,NRXN2" Pubmed 19036974 Disruption of Nectin-like 1 cell adhesion molecule leads to delayed axonal myelination in the CNS. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MBP,APC,CADM3,GFAP" Pubmed 17727731 Association analysis of chromosome 1 migraine candidate genes. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ATP1A2,CACNA1E,KCNJ9,KCNJ10" Pubmed 23522044 Cornichon proteins determine the subunit composition of synaptic AMPA receptors. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "CNIH2,GRIA1,GRIA2,CNIH3" Pubmed 16120608 "Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2." Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ACTN2,LRRC7,CAMK2A,CAMK2G" Pubmed 26586761 Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "NELL1,ROBO3,CNTN2,L1CAM" Pubmed 1332989 Expression of connexins in the developing olfactory system of the mouse. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "NCAM1,GFAP,GJB1,L1CAM" Pubmed 8201022 Expression of the tight junction protein ZO-1 in the olfactory system: presence of ZO-1 on olfactory sensory neurons and glial cells. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MBP,GFAP,TJP1,L1CAM" Pubmed 22529900 Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MAG,MBP,GFAP,OLIG2" Pubmed 11567616 Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "NKX6-2,NKX2-2,PAX6,OLIG2" Pubmed 14686897 "Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly." Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "KCNA1,KCNA2,KCNA4,KCNA6" Pubmed 26955760 Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "SOX10,TCF7L2,OLIG1,OLIG2" Pubmed 20610380 Ankyrin-B regulates Kir6.2 membrane expression and function in heart. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "ANK2,ABCC8,KCNJ11,ABCC9" Pubmed 18922769 Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "GRIA1,GRIA2,GRIA4,GRIK3" Pubmed 25866077 Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. Pubmed 5.36E-06 3.85E-01 1.27E-03 1.49E-02 4 6 "MAG,NCAM1,GFAP,CADM1" Pubmed 21829377 Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Pubmed 5.37E-06 3.86E-01 1.27E-03 1.49E-02 7 29 "FOXG1,NFIA,MYRF,FADS2,BEST1,LOC101926964,RAB3IL1" Pubmed 19409883 The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Pubmed 5.37E-06 3.86E-01 1.27E-03 1.49E-02 7 29 "SNCB,NEUROD1,UNC5D,GRIK4,PAX6,HES5,PROX1" Pubmed 24192035 A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Pubmed 5.37E-06 3.86E-01 1.27E-03 1.49E-02 7 29 "APC,GFAP,UNC5D,OMG,OPCML,PAX6,CA10" Pubmed 26839365 The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord. Pubmed 5.37E-06 3.86E-01 1.27E-03 1.49E-02 7 29 "GAD2,GFAP,NFIA,NKX2-2,PAX6,SLC17A6,OLIG2" Pubmed 20398908 Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Pubmed 5.66E-06 4.06E-01 1.33E-03 1.57E-02 10 67 "ACHE,ACTN2,NLGN1,SLC1A2,NRG3,GABBR1,GRIA1,GRIA2,NOS1AP,DLG2" Pubmed 15618518 Mouse brain organization revealed through direct genome-scale TF expression analysis. Pubmed 6.06E-06 4.35E-01 1.41E-03 1.66E-02 72 1689 "DPF1,SERPINA3,ZFYVE27,RBM10,RTN3,ARID1A,NDRG2,RXRG,FHL1,FOXG1,SOX6,FOXM1,TRIM46,TACC2,RUFY2,PKNOX2,ARFGAP2,ASCL1,SMARCE1,SOX1,MYT1L,SOX5,SOX10,NKX6-2,SALL3,KIF1B,NPAS3,RCOR2,NEUROD1,NFIA,ZNF638,NHLH1,NKX2-2,TBX15,ATF7,TCF7L2,ZEB1,TCF12,CECR2,AKNA,RFFL,ZFP91,MAEL,PAX6,ZMYND8,TLX1,UBTF,PRRX1,NSD2,BTBD17,POU3F2,POU3F4,MED1,RNF14,HES5,PROX1,ZBTB16,TOX,ZNF385B,PRDM2,ARNT2,OLIG1,DBX2,RTN4,RET,RFX4,JMJD1C,ZNF248,RNF220,LMO1,EN2,OLIG2" Pubmed 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 6.10E-06 4.38E-01 1.41E-03 1.66E-02 33 565 "NDRG2,ADD3,LRRC7,ANK3,PKP4,MAGI3,SORBS1,SHTN1,ARHGAP5,ARFGAP2,SHANK2,SNAP25,BCL2L2,ERBIN,GOLGB1,TJP1,TPD52,MAGI1,HNRNPK,ANLN,CCSER2,TJP2,PKN2,CTNND1,SIRPA,NAV2,WIPF2,ABI1,RTN4,NUP214,SH3GLB1,EPB41,EPB41L1" Pubmed 25285789 "Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor." Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "FABP7,SLIT1,SOX10,GFAP,OLIG2" Pubmed 16873704 Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "NEUROD1,ABCC8,NKX2-2,PAX6,KCNJ11" Pubmed 16225856 The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "NCAM1,ROBO3,CNTN2,PAX6,L1CAM" Pubmed 22318628 Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "FOXG1,PRKCZ,CTNND1,PCDH15,VANGL2" Pubmed 19318120 Fibroblast growth factor-2 increases the expression of neurogenic genes and promotes the migration and differentiation of neurons derived from transplanted neural stem/progenitor cells. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "ASCL1,NEUROD1,HES5,OLIG1,OLIG2" Pubmed 29106906 Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "AQP4,ALDH1L1,GFAP,NFIA,OLIG2" Pubmed 18590718 Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "NKX2-2,PAX6,HES5,PTCH1,OLIG2" Pubmed 28283561 Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "PDE4B,KCNA1,KCNA2,KCNA6,L1CAM" Pubmed 16723544 WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "MBP,APC,NFASC,KCNA1,OLIG2" Pubmed 22241839 Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "GRIA1,GRIK2,GRIK3,GRIN1,SLC17A6" Pubmed 26030886 "The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1." Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "NCAM1,GFAP,NEUROD1,PAX6,SLC17A6" Pubmed 16120638 Notch signaling coordinates the patterning of striatal compartments. Pubmed 6.28E-06 4.51E-01 1.41E-03 1.66E-02 5 12 "FOXG1,ASCL1,NEUROD1,GRIA1,HES5" Pubmed 19088125 Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome. Pubmed 6.49E-06 4.66E-01 1.44E-03 1.70E-02 6 20 "SLC6A9,NEUROD1,PAX6,PRKCG,PROX1,RLBP1" Pubmed 26659141 Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Pubmed 6.49E-06 4.66E-01 1.44E-03 1.70E-02 6 20 "DRAXIN,NTNG1,CNTN2,POU3F2,DSCAM,L1CAM" Pubmed 26798014 Oligodendrocyte precursors migrate along vasculature in the developing nervous system. Pubmed 6.49E-06 4.66E-01 1.44E-03 1.70E-02 6 20 "MBP,FABP7,APC,NKX2-2,OLIG1,OLIG2" Pubmed 25888505 Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Pubmed 6.49E-06 4.66E-01 1.44E-03 1.70E-02 6 20 "FABP7,ASCL1,SOX10,GFAP,PAX6,OLIG2" Pubmed 20080650 Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Pubmed 6.86E-06 4.92E-01 1.52E-03 1.79E-02 7 30 "MRVI1,RYR1,ANK2,PSD3,TUB,NXPH1,C2orf80" Pubmed 25640309 Systematic identification of molecular links between core and candidate genes in breast cancer. Pubmed 7.54E-06 5.41E-01 1.67E-03 1.96E-02 17 194 "TUBB4A,ACTL6B,BCAR3,APC,MADD,ATM,SNCB,ATP1A3,DKK3,TTC9B,CLASP2,GFAP,GNAS,SULT4A1,KLK6,EEF1A2,BAALC" Pubmed 26745185 The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Pubmed 7.65E-06 5.49E-01 1.68E-03 1.98E-02 9 55 "MBP,ASCL1,DLL3,SNAP25,ATM,GFAP,NKX2-2,PAX6,OLIG2" Pubmed 16000382 Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Pubmed 8.67E-06 6.22E-01 1.90E-03 2.24E-02 7 31 "DLL3,NEUROD1,NEURL1,RBPJ,HES5,ELAVL3,ELAVL4" Pubmed 18554416 Identification of transcripts with enriched expression in the developing and adult pancreas. Pubmed 8.76E-06 6.29E-01 1.90E-03 2.24E-02 33 575 "ACLY,ACTN2,SLC7A14,CADPS,SCG3,SPHKAP,SLIT1,SON,RAP1GAP2,NEUROD1,ABCC8,NKX2-2,NPPA,TCF7L2,HAP1,SYT6,TF,CELF3,PAX6,PCSK2,PDE1C,CHGA,GDAP1L1,DNAJC12,COL9A2,PRRX1,POU3F4,DNAJC6,CA10,ITIH2,KCNJ11,RAP1GAP,USH1C" Pubmed 17084361 SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "MBP,FABP7,SOX6,SOX5,SOX10,OLIG2" Pubmed 24167708 The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "ASCL1,NKX2-2,PAX6,SLC17A6,ELAVL3,ELAVL4" Pubmed 20562861 Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "NKX2-2,NODAL,LEFTY2,PAX6,VANGL2,OLIG2" Pubmed 17409257 Plexin-B2 controls the development of cerebellar granule cells. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "SEMA6A,GFAP,SEMA4A,CNTN2,PAX6,SLC17A6" Pubmed 19657336 SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "SOX6,ASCL1,SOX5,PAX6,SLC17A6,OLIG2" Pubmed 17321515 Activation of Class I transcription factors by low level Sonic hedgehog signaling is mediated by Gli2-dependent and independent mechanisms. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "ASCL1,NKX6-2,NKX2-2,PAX6,PTCH1,DBX2" Pubmed 17582329 Dlx transcription factors promote migration through repression of axon and dendrite growth. Pubmed 8.90E-06 6.39E-01 1.90E-03 2.24E-02 6 21 "MAPT,ASCL1,CADM1,HES5,ELMO1,DSCAM" Pubmed 27568519 Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Pubmed 8.91E-06 6.40E-01 1.90E-03 2.24E-02 9 56 "MEGF11,DKK3,SOX5,NKX6-2,PAX6,CDH8,CDH10,CDH20,OLIG2" Pubmed 21244100 Protein array based interactome analysis of amyloid-? indicates an inhibition of protein translation. Pubmed 8.95E-06 6.42E-01 1.91E-03 2.24E-02 22 305 "ATAT1,PDZD4,TRIM46,SGIP1,GPAM,ZCCHC17,ZNF365,ROBO3,PSRC1,SYT6,USP2,NSD2,PNKD,CTNND1,ZNF385B,HP1BP3,PARD6A,KCNN3,DNM2,RFX5,TTLL7,EPB41L2" Interaction int:DLG4 DLG4 interactions 1.26E-15 1.14E-11 1.14E-11 1.11E-10 48 272 "ACTN2,NLGN4X,LRRC7,ANK3,SORBS1,NLGN1,SLC1A2,SHANK2,ADGRA1,FYN,ATP2B2,TNIK,KIF1B,NCAM1,ERBIN,GPM6A,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRM3,PTPN5,INA,GUCY1A2,LGI1,PDE2A,ASIC3,NLGN3,DLGAP3,NRXN1,CNTN1,PPP3CB,PRKACB,PRKCG,ANKS1B,TUBB2B,LRP8,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ10,DLG2,DLG3,KIF2A,ABI1" Interaction int:AGAP2 AGAP2 interactions 3.35E-14 3.05E-10 1.52E-10 1.48E-09 38 193 "MAP6,LRRC7,ANK3,PPFIA1,PPM1E,SORBS1,NLGN1,SHANK2,TNIK,NCDN,GNAS,CACNA1E,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIN1,GRM3,INA,CDC42,TNR,DCLK1,PRMT8,NLGN3,DLGAP3,CRMP1,PPP3CB,PRKACB,PRKCG,PKN2,MAPK10,ANKS1B,SRGAP3,AK5,DLG2,DLG3,EPB41L1,EPB41L2" Interaction int:TNIK TNIK interactions 4.21E-13 3.83E-09 1.28E-09 1.24E-08 45 282 "LRRC7,TRIM46,ANK2,ANK3,SH3GL2,PPM1E,APC,SHANK2,SMARCE1,TNIK,RCOR2,SEPT3,WWC1,CACNA1A,CACNA1E,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIK2,GRIN1,SHISA7,INA,TJP1,TNR,PCDH8,CDH10,DCLK1,CAMKV,PPP3CB,PRKACB,DOCK7,PRKCG,CTNND1,CTNND2,CEP170,MAGI2,SRGAP3,KCNMA1,DLG2,DLG3,KIF2A,ABI1,PAK5,ABI2" Interaction int:DGUOK DGUOK interactions 5.81E-13 5.28E-09 1.32E-09 1.28E-08 22 71 "MAPT,HPCAL4,AMPH,ANK2,SNAP25,SNCB,ATP2B2,NCAM1,GPM6B,CAMK2A,GRIA2,DCLK1,HPCA,CAMKV,CNTN1,CRMP1,DPYSL5,NTM,L1CAM,EEF1A2,ELAVL4,EPB41L1" Interaction int:DLGAP1 DLGAP1 interactions 1.49E-12 1.35E-08 2.70E-09 2.62E-08 33 167 "LRRC7,ITSN1,APC,SORBS1,SHANK2,TNIK,ADGRB2,ERBIN,NCDN,SEPT3,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIN1,LGI1,PDE4B,DLGAP3,NRXN1,PPP3CB,PRKCG,CTNND1,CTNND2,DNAJC6,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ10,DLG2,DLG3,KIF2A,EPB41L1" Interaction int:DNAAF2 DNAAF2 interactions 1.81E-12 1.64E-08 2.73E-09 2.65E-08 23 82 "MAPT,HPCAL4,AMPH,ANK2,SNAP25,SNCB,PHYHIPL,ATP2B2,NCAM1,SEPT3,GPM6A,GPM6B,CAMK2A,GRIA2,DCLK1,HPCA,CAMKV,CNTN1,CRMP1,DPYSL5,DPP6,L1CAM,EPB41L1" Interaction int:NUFIP1 NUFIP1 interactions 1.81E-11 1.64E-07 2.35E-08 2.27E-07 26 116 "MAPT,HPCAL4,AMPH,ANK2,SNAP25,SNCB,ATP2B2,NCAM1,GLS,GPM6A,GPM6B,CAMK2A,GRIA2,DCLK1,PDE2A,HPCA,CAMKV,CNTN1,CRMP1,DPYSL5,CADM2,NTM,RAB5B,L1CAM,EEF1A2,EPB41L1" Interaction int:DLG1 DLG1 interactions 7.79E-10 7.08E-06 8.85E-07 8.58E-06 23 108 "ACTN2,ATP2B2,TNIK,KIF1B,BTRC,WWC1,CAMK2A,GRIA1,GRIK2,GRIN1,GUCY1A2,PAX6,DLGAP3,KCNA1,KCNA2,KCNA4,PTPRE,KCNC1,KCNJ4,KCNJ10,DLG2,DLG3,EPB41" Interaction int:SHANK3 SHANK3 interactions 3.28E-09 2.98E-05 3.31E-06 3.21E-05 28 166 "LRRC7,ANK3,SHANK2,TNIK,NFASC,NCDN,SEPT3,ARHGEF7,CAMK2A,CAMK2G,GRIN1,GRM3,INA,PAX6,TNR,DCLK1,DLGAP3,CNTN1,PPP3CB,NCAN,PRKCG,ANKS1B,SIRPA,DLG2,ABI1,RET,ABI2,EPB41L1" Interaction int:SYNGAP1 SYNGAP1 interactions 4.16E-08 3.78E-04 3.78E-05 3.66E-04 24 142 "LRRC7,AMPH,DGKZ,SORBS1,SHANK2,TNIK,ADGRB2,NCAM1,GNAS,CACNB2,CAMK2A,GRIA1,GRIA2,GRIN1,DLGAP3,CNRIP1,NCAN,PRKCG,ANKS1B,KCNA4,KCNJ10,DLG2,DLG3,EPB41L2" Interaction int:HAX1 HAX1 interactions 2.93E-07 2.66E-03 2.42E-04 2.34E-03 22 135 "MAPT,TUBB4A,AMPH,ANK2,DGKD,NCAM1,GPM6A,GPM6B,CAMK2A,GRIA2,DCLK1,HPCA,CAMKV,CNTN1,CRMP1,MAPK10,KIAA0513,DPYSL5,NTM,DPP6,L1CAM,EPB41L1" Interaction int:ARMC1 ARMC1 interactions 5.31E-07 4.83E-03 4.02E-04 3.90E-03 12 44 "EPS8,MAPT,SNCB,NCAM1,GPM6A,GPM6B,CAMK2A,CAMKV,CNTN1,CRMP1,DPYSL5,EPB41L1" Interaction int:NRXN1 NRXN1 interactions 1.10E-06 9.96E-03 7.66E-04 7.42E-03 11 39 "SYT9,APBA2,NLGN1,RPH3A,SYT4,SYT6,ATP13A2,NLGN3,NRXN1,NXPH1,SYTL2" Interaction int:DLG3 DLG3 interactions 1.45E-06 1.32E-02 9.42E-04 9.13E-03 16 84 "APC,NLGN1,ARFGAP1,ATP2B2,TNIK,KIF1B,CAMK2A,GRIK2,GRIN1,GUCY1A2,ZFP91,NLGN3,DLGAP3,KCNA4,DLG2,DLG3" Interaction int:NLGN1 NLGN1 interactions 1.83E-06 1.66E-02 1.11E-03 1.07E-02 6 10 "NLGN1,NLGN3,NRXN1,NRXN2,DLG2,DLG3" Transcription Factor Binding Site V$LBP1_Q6 V$LBP1_Q6 1.15E-14 6.99E-12 6.99E-12 4.89E-11 40 172 "ARID1A,KCNIP2,RXRG,FGR,TRIM46,SCN3B,B3GALT2,SOX5,KIF1B,C11orf87,PHLDB1,VAMP1,CACNB2,CAMK2G,SYT6,GRIK3,CRB1,TMEM25,CELF3,NEURL1,PCDH9,FNDC5,GPR37L1,HPSE2,HPCA,CABP1,SPATA6,PPP3CB,USP54,PSD,SYTL2,LRRTM3,KCNA2,KCNN3,DLG2,RAB5B,RGR,JMJD1C,VWA5A,BSCL2" Transcription Factor Binding Site CAGGTG_V$E12_Q6 CAGGTG_V$E12_Q6 1.41E-13 8.62E-11 4.31E-11 3.02E-10 184 1956 "TTYH1,EPS8,ASIC1,MAPT,ACLY,RTN3,ACTN2,EYA1,ARID1A,KCNIP2,RTN1,DSCAML1,RYR1,ADD3,GPR158,FGF1,PLA2G6,SEMA6A,C1QTNF4,ASIC4,FGR,HPCAL4,TRIM46,SELL,SEMA6C,ANK1,ANK2,ANK3,PKP4,SH3GL2,SESN3,DGKZ,DGKD,SLITRK3,TACC2,SORBS1,STK32C,RPH3A,SLC1A7,MADD,ARHGAP5,MT3,SHANK2,NSG2,SNAP25,ATM,FYN,SCN3B,WDTC1,SOX10,GAD2,AHCYL1,NKX6-2,ARPP21,ADGRB2,RAP1GAP2,NCAM1,LMO3,SMOC1,GFAP,GFRA1,NCDN,RCOR2,KIRREL3,GJB1,NEUROD1,SEPT3,NHLH1,SYT4,GNAS,ROBO3,GNG3,NODAL,CNTN2,GPM6B,CACNA1E,DDR1,NPPA,CACNB2,EML4,CAMK2A,CAMK2G,SYT6,GRIA1,GRIK3,GRIN1,ADAMTS8,OMG,SHISA7,CCKBR,USP2,FBXL16,GUCY1A1,TJP1,TLL2,CELF3,NEURL1,ZFP91,KCNK10,DAAM2,PAX6,PC,HRH3,TPM3,MAGI1,PDE1C,PDE2A,PDE4B,PDYN,CHRM1,PLEKHB1,CASC2,TMEFF2,SERPINE2,ZFYVE9,NRXN1,NEGR1,PIK3CD,UBTF,NMT2,FLRT1,FAM181B,NXPH1,POU3F2,POU3F4,CRMP1,PTPA,SNCAIP,RGS6,MICAL2,RIMS4,PHACTR3,RBPJ,CALY,PRKCG,PRKCZ,USP54,IGSF1,CTNND1,MAPK10,PROX1,MASP1,PSD,DPYSL5,PHYHIP,ZNF385B,CA10,PMEPA1,PTHLH,ELMO1,RGMA,STMN4,KCNA4,PTPRO,KCND3,SV2A,AK5,KCNJ4,KCNJ9,KCNJ11,KCNK1,PCDH15,KCNMA1,NAV2,KCNN3,DLG2,HS3ST4,RAB5B,CALN1,SLC17A6,DSCAM,RTN4,PAK5,JMJD1C,RGS7,PHC2,LMO1,SLC4A10,ELAVL3,ELAVL4,ROM1,BSCL2,EPB41,RASGRP2" Transcription Factor Binding Site V$LEF1_Q2 V$LEF1_Q2 1.03E-11 6.26E-09 2.09E-09 1.46E-08 36 174 "MRVI1,ARID1A,ADD3,SORCS1,SOX6,ANK3,SORBS1,SLC6A9,AHCYL1,ADGRB2,GFRA1,NCDN,RCOR2,RGL1,GNG3,NPPA,CACNB2,TCF7L2,DDR2,TMEM9,TLL2,PAX6,ZFYVE9,PRRX1,CTNND1,PROX1,LRRTM3,PRDM2,LRP8,SV2A,NAV2,SLC17A6,RET,LMO1,ELAVL4,BSCL2" Transcription Factor Binding Site V$NRSF_01 V$NRSF_01 3.25E-11 1.98E-08 4.26E-09 2.98E-08 23 78 "KCNIP2,APBB1,RPH3A,DDX25,SNAP25,PHYHIPL,ATP2B2,SCN3B,DNER,SYT4,SYT6,GRIN1,OMG,CELF3,PCSK2,CHGA,CHRNB2,GDAP1L1,SLC17A6,RASGRF1,L1CAM,ELAVL3,SEZ6" Transcription Factor Binding Site GGGAGGRR_V$MAZ_Q6 GGGAGGRR_V$MAZ_Q6 3.49E-11 2.13E-08 4.26E-09 2.98E-08 168 1838 "ASIC1,MAPT,APC2,RTN3,EYA1,ARID1A,RTKN,MDM4,KCNIP2,NDRG2,SLITRK1,RXRG,RYR1,ADD3,WAC,SORCS1,TUBB4A,FGF14,C1QTNF4,BCAR3,HPCAL4,TRIM46,AMPH,PKP4,PPM1E,APBB1,SESN3,DGKZ,SLITRK3,TACC2,SORBS1,NLGN1,SLC6A9,ARHGAP5,SHANK2,SLC14A1,CADPS,ASCL1,DLL3,ALDH4A1,SNAP25,SNCB,ATP1A2,ATP1A3,FYN,GABBR1,SCN3B,SON,SOX5,SOX10,NMNAT2,JPH4,ADAM15,KIF1B,GART,CPLX2,ADGRB2,NAP1L2,FXYD6,NCAM1,LMO3,BCL2L2,NCDN,RCOR2,FGF17,RGL1,KIRREL3,PHLDB1,PCDH11X,SYT4,NKX2-2,GNAS,ROBO3,NODAL,CNTN2,ADGRL3,KLHL4,GPM6B,ATF7,CACNB2,TCF7L2,GPR17,TCF12,CAMK2G,DDR2,GRIA1,GRIN1,PTPN5,USP2,CELF3,KCNK10,PAX6,REPS2,HPS5,PCDH9,RBFOX2,HRH3,TPM3,PCSK2,ZNF384,PDE2A,ADGRG1,CA14,CHRM1,PLEKHB1,CASC2,TUB,CHRNB2,HNRNPK,TLX1,HPCA,NLGN3,GDAP1L1,NRXN2,UBTF,FAM181B,CABP1,NXPH1,POU3F2,SF1,CRMP1,MICAL2,PHACTR3,RBPJ,PRKCG,USP54,IGSF1,CTNND1,CTNND2,MAPK10,PROX1,PSD,PHYHIP,PTAFR,CA10,PRTFDC1,COPS7A,RGMA,KCNC1,KCNJ4,KCNJ10,KCNJ11,KCNMA1,NAV2,DLG2,DLG3,RAB5B,CALN1,SLC17A6,RALGDS,DSCAM,CAMK1G,RFX4,RFX5,RGS7,ATL1,PHC2,SEC61A2,RPRD1A,ABI2,CBLN2,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2,EPB41L1,RASGRP2" Transcription Factor Binding Site CTTTGT_V$LEF1_Q2 CTTTGT_V$LEF1_Q2 1.19E-10 7.28E-08 1.21E-08 8.48E-08 146 1547 "DPF1,EPS8,MAPT,APC2,RTN3,EYA1,ARID1A,RTKN,CSMD3,NDRG2,RTN1,SLITRK1,ADD3,ADORA1,TUBB4A,SCN3A,SEMA6A,C1QTNF4,BCAR3,FHL1,BBOX1,SOX6,TRIM46,SEMA6C,SFPQ,ANK2,ANK3,SESN3,GAS7,DGKZ,TACC2,AQP4,LGI3,DLL3,SMARCE1,ATP1A3,FYN,B3GALT2,SOX5,SOX10,AHCYL1,ARPP21,SALL3,KIF1B,FXYD6,LMO3,ERBIN,GFRA1,RCOR2,GJB1,NEUROD1,GANAB,SEPT3,ARHGEF7,PCDH11X,SYT4,ASTN2,NKX2-2,BTRC,CNTN2,ADGRL3,KLHL4,ANO4,GPM6A,GPM6B,ATF7,CACNA1E,DDR1,TCF12,PTBP2,EML4,SYT6,GRIA1,GRIK2,GRIK3,GRIN1,GRM3,TF,OMG,OPCML,P2RX7,CELF3,ZFP91,KCNK10,PAX6,CDC42,PCDH9,RBFOX2,TPM3,PCSK2,PDYN,HMGB1,SCRG1,HPSE2,CA14,PFKFB3,CHRM1,HNRNPK,GDAP1L1,SEMA5B,PIK3CD,UBTF,CCSER2,FLRT1,VAV2,PLXNB3,COL9A2,PRRX1,P2RY12,ATCAY,NXPH1,SF1,CRMP1,ATRNL1,RIMS4,PHACTR3,RBPJ,DOCK7,USP54,ARHGEF4,PROX1,MASP1,PSD,DPYSL5,PRTFDC1,LRP8,RGMA,STMN4,PTPRO,DLG3,CAB39L,RALGDS,ABI1,FAM13C,RTN4,PAK5,L1CAM,USH1C,JMJD1C,PHC2,RLBP1,ARHGAP12,ELAVL3,ELAVL4,EN2,SEZ6" Transcription Factor Binding Site TGACCTY_V$ERR1_Q2 TGACCTY_V$ERR1_Q2 1.57E-10 9.59E-08 1.37E-08 9.58E-08 93 834 "ASIC1,RTN3,MRVI1,RTKN,KCNIP2,CSMD3,NDRG2,SLITRK1,SORCS1,TUBB4A,BCAR3,FHL1,HPCAL4,AMPH,CDC42BPA,ANK3,SH3GL2,PPM1E,APBA2,RPH3A,MADD,PKNOX2,SLC6A9,ARFGAP2,ATP1A3,SOX5,AHCYL1,ADAM15,DNER,RAP1GAP2,LMO3,NDUFA5,SMOC1,GFAP,NCDN,RCOR2,KIRREL3,VAMP1,ASTN2,CNTN2,ANO4,CACNB2,TCF7L2,DIRAS1,CAMK2G,GRIA4,GRIK3,TF,SHISA7,USP2,TLL2,NEURL1,ZFP91,PAX6,HRH3,TPM3,TPM4,PCSK2,PDE1A,FNDC5,CHGA,ZFYVE9,NRXN1,NRXN2,CCSER2,SLC25A27,PACSIN1,IFFO1,POU3F2,RNF14,PHACTR3,MASP1,LRRTM3,PMEPA1,COPS7A,CDH20,KCNC1,PARD6A,KCND3,SV2A,KCNK1,KCNN3,DLG2,PYGM,CRTAC1,RFX5,JMJD1C,RGS7,EEF1A2,ELAVL3,ELAVL4,RCAN2,RASGRP2" Transcription Factor Binding Site CAGCTG_V$AP4_Q5 CAGCTG_V$AP4_Q5 7.38E-10 4.50E-07 5.63E-08 3.93E-07 118 1192 "MBP,EXTL1,EYA1,MRVI1,ARID1A,RTKN,KCNIP2,CSMD3,RXRG,RYR1,TUBB4A,FGF1,FGF14,FGR,MOG,TRIM46,AMPH,ANK1,ANK2,ITSN1,PPM1E,APBA2,GAS7,SORBS1,SLC1A7,SLC8A3,NSG2,CADPS,LGI3,DLL3,ATP1A2,SCN3B,MYBPC1,WDTC1,B3GALT2,SOX5,SOX10,ZSWIM8,ARPP21,KIF1B,C11orf87,BCL2L2,NCDN,RCOR2,FGF17,PHLDB1,SEPT3,VAMP1,NKX2-2,SEMA4A,GNG3,CDK5R2,CNTN2,ADGRL3,GPM6B,DDR1,NPPA,CACNB2,GPR17,TCF12,CAMK2G,SYT6,GRIK3,ADAMTS8,OMG,OPCML,CRB1,TMEM25,CELF3,NEURL1,REPS2,PADI2,PCDH9,RBFOX2,LGI1,TPM3,ZNF384,PDE1A,FNDC5,GPR37L1,HAPLN2,HPSE2,HPCA,NLGN3,UBTF,PLXNB3,CABP1,SPATA6,RNF14,PPP2R5C,PPP3CB,RGS6,PRKCG,USP54,MASP1,PSD,SYTL2,LRRTM3,KCNA2,SV2A,KCNMA1,KCNN3,DLG2,PYGM,HS3ST4,RAB5B,DSCAM,PAK5,L1CAM,RGR,JMJD1C,RGS7,GPR61,ABI2,VWA5A,ELAVL3,BSCL2,SEZ6" Transcription Factor Binding Site GCANCTGNY_V$MYOD_Q6 GCANCTGNY_V$MYOD_Q6 2.07E-09 1.26E-06 1.40E-07 9.79E-07 81 721 "EYA1,RTKN,CSMD3,RXRG,TUBB4A,GPR158,FGR,TRIM46,ANK1,ANK2,PKP4,SLC8A3,NSG2,CADPS,DLL3,ATP1A3,FYN,SCN3B,B3GALT2,SOX5,NKX6-2,KIF1B,ADGRB2,NCAM1,LMO3,C11orf87,GFAP,GFRA1,FGF17,NEUROD1,VAMP1,NHLH1,SYT4,ROBO3,CDK5R2,ADGRL3,CACNB2,TCF12,NRGN,SYT6,GRIK3,ADAMTS8,SHISA7,OPCML,CRB1,USP2,GUCY1A1,TJP1,CELF3,NEURL1,ZFP91,REPS2,PCDH9,CDH10,PCSK2,PDE1A,FNDC5,GPR37L1,HPCA,NRXN2,NEGR1,CABP1,PPP3CB,PHACTR3,PRKCG,USP54,PROX1,MASP1,PSD,SYTL2,DPYSL5,LRRTM3,SV2A,PCDH15,KCNN3,DLG2,RAB5B,VWA5A,ELAVL3,ELAVL4,SEZ6" Transcription Factor Binding Site V$MAZ_Q6 V$MAZ_Q6 2.53E-09 1.54E-06 1.54E-07 1.08E-06 29 145 "ARID1A,MDM4,KCNIP2,WAC,TRIM46,APBB1,CLSTN1,ADGRB2,GFRA1,NCDN,RCOR2,NPPA,TCF7L2,CAMK2G,GRIK3,PTPN5,NEURL1,ZFP91,PAX6,HPS5,TPM3,CA14,TLX1,HPCA,CTNND1,PROX1,KCNC1,RFX5,PHC2" Transcription Factor Binding Site AACTTT_UNKNOWN AACTTT_UNKNOWN 3.02E-09 1.84E-06 1.68E-07 1.17E-06 140 1531 "EYA1,MRVI1,ARID1A,CSMD3,ADCY2,DSCAML1,SLITRK1,ADD3,SCN4B,LRRTM4,FGF14,SEMA6A,BCAR3,UNC79,SOX6,ANK3,ITSN1,SH3GL2,PPM1E,SESN3,DGKD,SLITRK3,SORBS1,NLGN1,SHANK2,NSG2,DACH2,CADPS,SORCS3,MYBPC1,SOX1,SOX5,ARPP21,SALL3,NEK6,ADGRB2,NPAS3,SPART,LMO3,C11orf87,SMOC1,GFRA1,NCDN,RCOR2,NELL1,KIRREL3,NEUROD1,NFIA,ARHGEF7,GLS,PCDH11X,NHLH1,NKX2-2,GNAS,GNG4,BTRC,ATF7,CACNA1E,CACNB2,TCF7L2,TCF12,PTBP2,CAMK2A,DDR2,SYT6,NUCB1,GRIK3,GRM3,CELF3,ZDHHC22,DAAM2,PAX6,REPS2,PCDH8,PCDH9,CDH10,HRH3,SEZ6L,TPM3,MAGI1,PDE1A,PDE2A,PDE4B,PDYN,HMGB1,HPSE2,TMEFF2,NLGN3,NRXN1,NMT2,CCSER2,CNTN1,CABP1,PRRX1,NSD2,NXPH1,ACBD5,CP,POU3F2,POU3F4,RNF14,SNCAIP,PHACTR3,PRKAB2,PRKACB,PRKCG,CTNND1,CTNND2,MAPK10,PROX1,FGFR1OP2,SYTL2,PHYHIP,LRRTM3,CA10,PMEPA1,PTHLH,ITIH2,ELMO1,LRP8,RGMA,STMN4,KCND3,NTM,KCNMA1,SNX27,DLG2,HS3ST4,CALN1,FAM13C,SLC6A15,CRTAC1,RFX4,RFX5,PHC2,SFXN5,GPR61,SLC4A10,ELAVL4,RCAN2" Transcription Factor Binding Site V$E2F_Q2 V$E2F_Q2 1.71E-08 1.04E-05 8.68E-07 6.07E-06 26 130 "WAC,SFPQ,CLSTN1,SCMH1,PHYHIPL,KIF1B,ADGRB2,NCDN,GNG4,CNTN2,SYT6,GRIK3,CDC42,TPM3,HPCA,ZFYVE9,NEGR1,PRKACB,PUM1,LRP8,KCND3,SNX27,FAM13C,RGS7,EFNA3,ARHGAP12" Transcription Factor Binding Site CTGCAGY_UNKNOWN CTGCAGY_UNKNOWN 2.35E-08 1.43E-05 1.10E-06 7.70E-06 69 607 "MAPT,APC2,RTKN,SLITRK1,ADD3,FGF1,FGF14,SEMA6A,FHL1,ANK3,SLITRK3,TACC2,ATP1A3,FYN,B3GALT2,SOX10,ZSWIM8,ADGRB2,NAP1L2,LMO3,C11orf87,NCDN,RCOR2,RGL1,GANAB,GNG3,CDK5R2,CNTN2,GPM6A,CACNB2,CAMK2G,GRIA4,GRIK2,OMG,SHISA7,OPCML,PAX6,PCDH9,DCLK1,RBFOX2,HRH3,FNDC5,HPSE2,CHGA,NLGN3,NRXN1,SEMA5B,IFFO1,PPP2R5C,PHACTR3,IGSF1,CTNND1,CTNND2,PSD,SYTL2,ELMO1,KCNN3,DLG2,DLG3,RAB5B,CALN1,DSCAM,RTN4,JMJD1C,GPR61,SLC4A10,ELAVL4,BSCL2,EPB41" Transcription Factor Binding Site V$TFIII_Q6 V$TFIII_Q6 3.75E-08 2.29E-05 1.63E-06 1.14E-05 30 172 "APC2,NDRG2,FGF14,FOXG1,TRIM46,DGKZ,ARHGAP5,SHANK2,ASCL1,ATP1A2,WDTC1,LMO3,BCL2L2,NCDN,RCOR2,NKX2-2,GNAS,NODAL,CNTN2,TCF12,PCDH9,CHRM1,UBTF,PRRX1,SF1,MICAL2,CA10,KCNJ10,RAB5B,ELAVL3" Transcription Factor Binding Site V$ETF_Q6 V$ETF_Q6 4.55E-08 2.78E-05 1.85E-06 1.29E-05 20 85 "ARID1A,RXRG,WAC,CDC7,HPCAL4,CLSTN1,ZSWIM8,EMC1,NFIA,CACNA1E,CAMK2G,GRIK3,ZFYVE9,SPATA6,PPP3CB,PRKACB,LRP8,KCND3,FAM13C,EFNA3" Transcription Factor Binding Site CAGNWMCNNNGAC_UNKNOWN CAGNWMCNNNGAC_UNKNOWN 6.28E-08 3.83E-05 2.39E-06 1.67E-05 18 71 "KCNIP2,CSMD3,RPH3A,PHYHIPL,SCN3B,DNER,SYT4,SYT6,GRIN1,OMG,CELF3,CHGA,CHRNB2,HPCA,SLC17A6,L1CAM,JMJD1C,ELAVL3" Transcription Factor Binding Site V$HEB_Q6 V$HEB_Q6 7.31E-08 4.46E-05 2.62E-06 1.83E-05 34 217 "RTN3,RTKN,CSMD3,RXRG,TRIM46,ITSN1,GAS7,SORBS1,SLC1A7,CADPS,SOX5,ZSWIM8,BCL2L2,RCOR2,CDK5R2,CNTN2,ADGRL3,CACNB2,SYT6,GRIK3,ADAMTS8,USP2,CELF3,FNDC5,GPR37L1,HPCA,UBTF,PLXNB3,PSD,SYTL2,DLG2,L1CAM,RGS7,SEZ6" Transcription Factor Binding Site V$AP4_Q6_01 V$AP4_Q6_01 8.40E-08 5.13E-05 2.85E-06 1.99E-05 33 208 "EYA1,RTKN,CSMD3,RXRG,TUBB4A,TRIM46,ANK1,GAS7,SORBS1,CADPS,ZSWIM8,BCL2L2,FGF17,CDK5R2,CNTN2,ADGRL3,SYT6,GRIK3,CELF3,NEURL1,FNDC5,GPR37L1,HPCA,PPP3CB,PRKCG,USP54,MASP1,PSD,SYTL2,DLG2,RAB5B,VWA5A,SEZ6" Transcription Factor Binding Site V$EFC_Q6 V$EFC_Q6 1.15E-07 7.03E-05 3.70E-06 2.59E-05 34 221 "ACER3,EYA1,ARID1A,B3GALT2,FXYD6,NPAS3,LMO3,BCL2L2,RGL1,ROBO3,BTRC,NRGN,CAMK2A,SYT6,PAX6,PDE1A,NLGN3,SEMA5B,FLRT1,PRRX1,PPP3CB,PSD,DPYSL5,STMN4,KCNA1,KCNA2,KCNN3,DNAH9,SLC17A6,RFX4,SLC39A12,ABI2,ELAVL4,EN2" Transcription Factor Binding Site V$AP4_Q6 V$AP4_Q6 2.27E-07 1.38E-04 6.91E-06 4.83E-05 29 176 "EYA1,ARID1A,RTKN,RXRG,AMPH,GAS7,SORBS1,CADPS,DLL3,WDTC1,ZSWIM8,BCL2L2,PHLDB1,GNG3,NPPA,CACNB2,GRIK3,CELF3,TPM3,FNDC5,HAPLN2,UBTF,PLXNB3,SYTL2,KCNMA1,HS3ST4,JMJD1C,RGS7,BSCL2" Transcription Factor Binding Site V$SRY_01 V$SRY_01 2.79E-07 1.70E-04 8.10E-06 5.66E-05 27 158 "SOX6,ANK3,SORBS1,CLSTN1,B3GALT2,SOX5,NMNAT2,NCAM1,LMO3,GFRA1,NFIA,ATF7,CACNA1E,TCF7L2,OPCML,PAX6,LGI1,PDE3B,CA14,PIK3CD,PRRX1,KCNA1,DLG2,RFX4,JMJD1C,SH3GLB1,ELAVL4" Transcription Factor Binding Site TGACATY_UNKNOWN TGACATY_UNKNOWN 3.17E-07 1.93E-04 8.79E-06 6.15E-05 60 534 "PRR5L,RBM10,EYA1,CSMD3,ADARB2,C1QTNF4,FOXG1,RASA3,SESN3,GAS7,TACC2,SORBS1,STK32C,MADD,SLN,FYN,SCN3B,WDTC1,ADGRB2,NPAS3,LMO3,NCDN,SYT4,NKX2-2,GNG3,DDR1,GRIA4,TJP1,CELF3,ZFP91,CDH10,TPM3,PCSK2,PDE1C,HAPLN2,GDAP1L1,CCSER2,NXPH1,POU3F4,RNF14,PPP2R5C,SNCAIP,RGS6,MICAL2,CTNND1,CTNND2,MAPK10,PTHLH,ELMO1,STMN4,PTPRD,KCNK1,DLG2,PYGM,RFX4,ARHGAP12,ELAVL4,BSCL2,OLIG2,RCAN2" Transcription Factor Binding Site V$TEF1_Q6 V$TEF1_Q6 3.70E-07 2.26E-04 9.82E-06 6.87E-05 29 180 "RTN3,PAQR6,ARID1A,KCNIP2,ADD3,BBOX1,ANK3,PPFIA1,SLC1A7,MADD,SLC6A9,KIF1B,FXYD6,KIRREL3,CACNA1E,USP2,CELF3,PADI2,ZNF384,CA14,TLX1,CCSER2,PRRX1,SYTL2,DLG2,SLC17A6,JMJD1C,ELAVL4,RASGRP2" Transcription Factor Binding Site V$USF2_Q6 V$USF2_Q6 1.12E-06 6.85E-04 2.85E-05 1.99E-04 30 200 "TESK2,HPCAL4,TRIM46,SLC1A7,B3GALT2,NMNAT2,EMC1,ADGRB2,FXYD6,RCOR2,RGL1,SLCO1C1,SYT6,USP2,GUCY1A2,ZFP91,PAX6,HPS5,CA14,PFKFB3,CHRM1,HPCA,MICAL2,LRP8,COPS7A,RAB3IL1,RFX5,ARHGAP12,EPB41,RASGRP2" Transcription Factor Binding Site TGCTGAY_UNKNOWN TGCTGAY_UNKNOWN 2.35E-06 1.43E-03 5.73E-05 4.01E-04 50 440 "ASIC1,ADARB2,SLITRK1,GALNT13,RYR1,LRRTM4,ANK3,PKP4,PPM1E,DGKZ,SLITRK3,USP16,MADD,SNAP25,SNCB,FYN,GABBR1,SON,GAD2,GART,ADGRB2,FXYD6,LMO3,NCDN,SLCO1C1,NHLH1,SYT4,GPM6B,CACNA1E,CAMK2A,OMG,USP2,CDH10,TPM4,ZNF384,PDE1C,PFKFB3,TUB,POU3F4,PPP2R5C,CTNND1,CA10,STMN4,KCNA1,KCND3,NAV2,RAB5B,JMJD1C,RLBP1,SEZ6" Transcription Factor Binding Site GGGTGGRR_V$PAX4_03 GGGTGGRR_V$PAX4_03 3.70E-06 2.26E-03 8.68E-05 6.07E-04 96 1068 "DPF1,ASIC1,MAPT,EMID1,RTN3,RTKN,NDRG2,ADD3,WAC,TUBB4A,LRRTM4,SEMA6A,BCAR3,FHL1,HPCAL4,TRIM46,SEMA6C,ANK2,ANXA7,SLITRK3,AQP4,ARHGAP5,ATP1A3,FYN,SCN3B,SOX10,ADGRB2,C11orf87,NCDN,RCOR2,FGF17,SEPT3,NHLH1,ROBO3,CDK5R2,CNTN2,CACNA1A,GPM6B,ATF7,CACNA1E,GPR17,SYT6,GRIK3,GRM3,USP2,FBXL16,ZFP91,KCNK10,PAX6,SEZ6L,TPM3,PCSK2,FNDC5,HPSE2,CHRM1,TUB,HNRNPK,NLGN3,NEGR1,PLXNB3,PRRX1,NXPH1,ACBD5,POU3F4,PHACTR3,DZIP3,PRKCG,IGSF1,CTNND1,CTNND2,FGFR1OP2,PSD,DPYSL5,PHYHIP,CA10,RGMA,STMN4,KCNA1,KCND3,KCNN3,DLG2,PYGM,DLG3,HS3ST4,ABI1,RTN4,CRTAC1,JMJD1C,EEF1A2,RPRD1A,ABI2,ELAVL3,ELAVL4,EN2,RASGRP2,SEZ6" Transcription Factor Binding Site V$MYC_Q2 V$MYC_Q2 4.27E-06 2.61E-03 9.65E-05 6.75E-04 24 150 "TESK2,HPCAL4,TRIM46,SLC1A7,B3GALT2,EMC1,FXYD6,RCOR2,SYT6,USP2,ZFP91,PAX6,HPS5,CA14,PFKFB3,CHRM1,HPCA,MICAL2,LRP8,COPS7A,RAB3IL1,SLC6A15,RFX5,EPB41" Transcription Factor Binding Site TGTTTGY_V$HNF3_Q6 TGTTTGY_V$HNF3_Q6 5.80E-06 3.54E-03 1.26E-04 8.84E-04 61 596 "EYA1,ADARB2,RTN1,FGF14,SEMA6A,SESN3,APC,BCAS1,SLC14A1,SCG3,SLCO1A2,SORCS3,SNAP25,SNCB,B3GALT2,SOX5,ZSWIM8,NMNAT2,JPH4,ARPP21,NEK6,ADAM15,ADGRB2,NCAM1,SMOC1,NCDN,KIRREL3,NEUROD1,NFIA,PCDH11X,NKX2-2,ROBO3,GOLGB1,GPM6A,TCF7L2,GRIK2,TF,OMG,TJP1,REPS2,CDH10,PCSK2,PDE3B,PDYN,HPSE2,CA14,CHRM1,SEMA5B,CCSER2,FLRT1,CNTN1,MAPK10,MASP1,DLG2,RAB5B,DSCAM,FAM13C,RFX4,ELAVL4,ROM1,RPE65" Transcription Factor Binding Site V$MYOD_Q6 V$MYOD_Q6 9.94E-06 6.07E-03 2.09E-04 1.46E-03 28 200 "DSCAML1,SELL,ANK2,PKP4,DGKD,NSG2,B3GALT2,NKX6-2,ARPP21,GFRA1,FGF17,RND1,NHLH1,SYT4,GNAS,USP2,GUCY1A1,TJP1,FNDC5,PTPA,PHACTR3,RBPJ,PRKCG,PROX1,KCNN3,DSCAM,ELAVL3,ELAVL4" Transcription Factor Binding Site V$FOXJ2_02 V$FOXJ2_02 1.08E-05 6.61E-03 2.20E-04 1.54E-03 27 190 "CSMD3,SLCO1A2,JPH4,ARPP21,LMO3,KIRREL3,NFIA,GPM6B,ATF7,SYT6,OLR1,USP2,PAX6,CDH10,PDE4B,HPSE2,NRXN1,IFFO1,POU3F4,FEZ1,ATRNL1,PHACTR3,LRRTM3,PTHLH,CDH20,PTPRO,RAB5B" Transcription Factor Binding Site GTTRYCATRR_UNKNOWN GTTRYCATRR_UNKNOWN 1.14E-05 6.94E-03 2.22E-04 1.55E-03 21 128 "KCNIP2,TUBB4A,HPCAL4,ANK2,PPM1E,ATP1A3,FYN,FXYD6,LMO3,NCDN,GPR17,CAMK2A,SYT6,NLGN3,SPATA6,CALY,PRKCG,MAPK10,PSD,ELMO1,RFX4" Transcription Factor Binding Site RYTGCNWTGGNR_UNKNOWN RYTGCNWTGGNR_UNKNOWN 1.16E-05 7.09E-03 2.22E-04 1.55E-03 17 90 "HPCAL4,ANK2,ITSN1,PPM1E,SLC8A3,FXYD6,NCDN,DDR1,CACNB2,CAMK2A,SYT6,NLGN3,CALY,MAPK10,LRRTM3,RFX4,SLC39A12" Transcription Factor Binding Site V$ZF5_01 V$ZF5_01 1.45E-05 8.85E-03 2.68E-04 1.87E-03 27 193 "ASIC1,DSCAML1,APBB1,SORCS3,KIF1B,KIRREL3,ARHGEF7,ABCC8,BTRC,CACNA1A,GRIK3,NEURL1,DCLK1,TLX1,HPCA,UBTF,CA10,LRP8,KCNC1,KCND3,DNM2,RASGRF1,FAM13C,RGS7,PHC2,ELAVL3,SEZ6" Transcription Factor Binding Site V$NKX61_01 V$NKX61_01 2.12E-05 1.29E-02 3.80E-04 2.65E-03 26 186 "EYA1,KCNIP2,FHL1,PPM1E,SESN3,SLITRK3,SOX5,GAD2,SALL3,LMO3,CDK11B,CDH10,SEZ6L,LGI1,PCSK2,CCSER2,PRRX1,POU3F4,PPP3CB,CTNND1,PTPRD,SV2A,KCNN3,RAB5B,SLC6A15,LMO1" Transcription Factor Binding Site V$MYOGENIN_Q6 V$MYOGENIN_Q6 2.32E-05 1.42E-02 4.04E-04 2.83E-03 27 198 "ARID1A,RTKN,KCNIP2,SORCS1,TUBB4A,FGR,DGKZ,WDTC1,NKX6-2,C11orf87,SMOC1,GFRA1,SYT4,SYT6,GRIK3,ADAMTS8,TJP1,ZFP91,GPR37L1,ZFYVE9,NEGR1,UBTF,FLRT1,CABP1,KCNA2,ELAVL3,SEZ6" Transcription Factor Binding Site V$RORA1_01 V$RORA1_01 2.79E-05 1.70E-02 4.72E-04 3.30E-03 27 200 "ABAT,CDHR1,RTN3,MRVI1,NDRG2,RYR1,SORCS1,URGCP,SLC8A3,SCMH1,ASPH,B3GALT2,LMO3,VAMP1,CNTN2,CACNA1A,CACNB2,GRIA1,GRIK3,TPM3,SLC22A6,SLC25A27,PACSIN1,RGS6,JMJD1C,EFNA3,ELAVL4" Transcription Factor Binding Site V$SOX5_01 V$SOX5_01 2.98E-05 1.82E-02 4.91E-04 3.44E-03 28 212 "TUBB4A,SEMA6A,SOX6,SEMA6C,ANK2,ANK3,ZNF365,SOX5,SALL3,NASP,NCAM1,LMO3,NFIA,TCF12,EML4,RBFOX2,PCSK2,HAPLN2,CASC2,POU3F4,ATRNL1,PUM1,ZNF385B,LRRTM3,DLG2,CAMK1G,ELAVL4,EN2" Transcription Factor Binding Site V$RFX1_02 V$RFX1_02 3.64E-05 2.22E-02 5.75E-04 4.02E-03 27 203 "KCNIP2,CSMD3,TUBB4A,HPCAL4,ANK2,ITSN1,PPM1E,GAS7,SLC8A3,ATP1A3,FXYD6,GPR17,CAMK2A,SYT6,TUB,RGS6,CALY,PRKCG,MAPK10,PUM1,PSD,ELMO1,KCNJ9,SLC17A6,RFX4,ATL1,ELAVL3" Transcription Factor Binding Site V$CREBP1_01 V$CREBP1_01 3.67E-05 2.24E-02 5.75E-04 4.02E-03 21 138 "EYA1,FGF14,CLSTN1,GPM6A,SYT6,USP2,CDC42,HRH3,PCSK2,SERPINE2,ZFYVE9,NEGR1,RGS6,LRRTM3,PMEPA1,PTHLH,KCNC1,CRTAC1,JMJD1C,ELAVL4,EPB41" Transcription Factor Binding Site V$E2A_Q2 V$E2A_Q2 4.06E-05 2.47E-02 6.18E-04 4.32E-03 26 193 "KCNIP2,DGKZ,DGKD,NSG2,LGI3,WDTC1,ADGRB2,C11orf87,GJB1,SEPT3,GNAS,CNTN2,CAMK2G,SYT6,GRIK3,GRIN1,USP2,FNDC5,PTPA,PHACTR3,MASP1,PSD,KCNMA1,DSCAM,ELAVL3,ELAVL4" Transcription Factor Binding Site V$MYOD_01 V$MYOD_01 4.34E-05 2.64E-02 6.45E-04 4.51E-03 27 205 "CSMD3,RXRG,ITSN1,DGKD,MT3,SHANK2,NSG2,NCDN,NHLH1,SYT4,GNAS,CACNB2,CAMK2A,OMG,SHISA7,HRH3,FNDC5,HPSE2,CALY,USP54,PSD,CA10,ELMO1,KCNN3,CALN1,DSCAM,ELAVL4" Transcription Factor Binding Site V$MYOD_Q6_01 V$MYOD_Q6_01 4.85E-05 2.96E-02 7.04E-04 4.92E-03 26 195 "KCNIP2,SELL,APBB1,DGKD,MT3,WDTC1,NHLH1,GNAS,CDK5R2,CAMK2A,GRIK3,GRIN1,NEURL1,HRH3,ZFYVE9,UBTF,PSD,ELMO1,KCNA4,KCND3,DSCAM,JMJD1C,ELAVL3,ELAVL4,RCAN2,SEZ6" Transcription Factor Binding Site V$FOXM1_01 V$FOXM1_01 5.60E-05 3.42E-02 7.95E-04 5.56E-03 27 208 "ASIC1,RTKN,SLITRK1,FABP7,FOXG1,MADD,SNAP25,SOX5,SALL3,NCAM1,LMO3,NCDN,NEUROD1,CNTN2,TCF12,GRM3,P2RX7,PAX6,PCDH9,CDH10,POU3F4,PUM1,KCNA2,RASGRF1,RTN4,SLC4A10,ELAVL4" Transcription Factor Binding Site TGATTTRY_V$GFI1_01 TGATTTRY_V$GFI1_01 6.17E-05 3.76E-02 8.54E-04 5.97E-03 30 244 "SLC25A25,RXRG,FGF14,ITSN1,MSR1,SNAP25,FYN,MYBPC1,SOX5,NMNAT2,JPH4,ROBO3,GPM6A,CACNA1E,GPR17,TCF12,CRB1,NRXN1,CCSER2,FLRT1,POU3F2,CTNND1,MAPK8,MAPK10,CAB39L,HS3ST4,CALN1,JMJD1C,PHC2,ELAVL4" Transcription Factor Binding Site V$MEF2_03 V$MEF2_03 6.30E-05 3.84E-02 8.54E-04 5.97E-03 26 198 "EXTL1,EYA1,NDRG2,ADCY2,LRRTM4,SLC8A3,SHANK2,ATP1A2,SOX5,ARPP21,MIR4697HG,DIRAS1,USP2,CNTN1,PRRX1,CTNND2,ZNF385B,PMEPA1,PTPRO,SV2A,KCNJ9,DLG2,RASGRF1,RFX4,SSPN,ELAVL4" Transcription Factor Binding Site V$AP1_Q2_01 V$AP1_Q2_01 6.53E-05 3.98E-02 8.66E-04 6.05E-03 29 233 "RTN3,EYA1,NDRG2,TUBB4A,GPR158,TRIM46,ANK3,SHANK2,SNCB,ADAM15,RAP1GAP2,GFAP,NCDN,TCF12,DIRAS1,DDR2,OLR1,OMG,KCNK10,PCDH9,HPSE2,CHRM1,NLGN3,RBPJ,ZNF385B,RTN4,SFXN5,ELAVL4,EPB41L1" Transcription Factor Binding Site V$ZIC3_01 V$ZIC3_01 8.47E-05 5.17E-02 1.10E-03 7.69E-03 27 213 "PAQR6,SLITRK3,SCN3B,ZSWIM8,BCL2L2,RCOR2,GJB1,NHLH1,NKX2-2,GNAS,CDK5R2,GRIK3,ZFP91,PAX6,ZNF384,CA14,HPCA,NLGN3,NRXN1,NEGR1,CTNND1,MAPK10,LRRTM3,CA10,LRP8,PYGM,RBM12" Transcription Factor Binding Site V$SF1_Q6 V$SF1_Q6 1.04E-04 6.36E-02 1.33E-03 9.27E-03 26 204 "ABAT,CDHR1,NDRG2,SLITRK1,TUBB4A,PPM1E,APBB1,RPH3A,MADD,ARFGAP2,NCDN,KIRREL3,CNTN2,CACNB2,DIRAS1,CAMK2G,PTPN5,FNDC5,CHGA,NRXN2,KCNC1,SV2A,KCNK1,RGS7,ELAVL3,RASGRP2" Transcription Factor Binding Site V$GATA_C V$GATA_C 1.08E-04 6.57E-02 1.34E-03 9.38E-03 27 216 "EYA1,ADORA3,FGF14,PPM1E,MSR1,SPHKAP,GABBR1,B3GALT2,SOX5,SOX10,ZSWIM8,CPLX2,SLCO1C1,PCDH11X,BTRC,GRIK3,LGI1,TPM3,HPSE2,CPT1C,CCSER2,P2RY12,CTNND1,MASP1,ZNF385B,HS3ST4,ELAVL4" Transcription Factor Binding Site V$OLF1_01 V$OLF1_01 1.26E-04 7.69E-02 1.54E-03 1.08E-02 27 218 "MRVI1,SCN4B,SLC6A9,ATP1A2,SOX5,GFRA1,ROBO3,CACNA1E,SYT6,CCKBR,HPSE2,CA14,NLGN3,UBTF,PPP3CB,PRKCG,IGSF1,PSD,DPYSL5,PTHLH,DLG3,HS3ST4,OLIG1,SLC17A6,RLBP1,GPR61,ELAVL3" Transcription Factor Binding Site TTANTCA_UNKNOWN TTANTCA_UNKNOWN 1.34E-04 8.17E-02 1.60E-03 1.12E-02 68 760 "RTN3,EYA1,KCNIP2,RTN1,SLITRK1,GPR158,PLA2G6,BCAR3,NLGN1,RPH3A,ARFGAP2,SLC8A3,SHANK2,NSG2,ASCL1,SCN3B,B3GALT2,SOX5,SOX10,ARPP21,KIF1B,LMO3,C11orf87,ERBIN,GFRA1,NCDN,RGL1,KIRREL3,PCDH11X,NHLH1,ROBO3,GPM6A,NUMA1,GPR88,OMG,USP2,ZFP91,PAX6,PCDH9,DCLK1,MAGI1,PDE1A,HPSE2,TMEFF2,SEMA5B,NMT2,TJP2,PRRX1,POU3F4,ATRNL1,DOCK7,CTNND2,MAPK8,PROX1,MASP1,SYTL2,ITIH2,STMN4,CDH20,PTPRO,DLG2,HS3ST4,SLC17A6,L1CAM,CRTAC1,RFX4,JMJD1C,SEZ6" Transcription Factor Binding Site CTTTGA_V$LEF1_Q2 CTTTGA_V$LEF1_Q2 1.61E-04 9.80E-02 1.88E-03 1.32E-02 83 981 "EMID1,MBP,EYA1,MRVI1,ARID1A,RTN1,ADD3,SORCS1,SCN3A,FGF14,SOX6,ANK3,SESN3,GAS7,SORBS1,URGCP,SLC6A9,SLC14A1,CADPS,SCG3,ASPH,SLN,SNAP25,SOX5,AHCYL1,ARPP21,ADGRB2,GFRA1,NCDN,RCOR2,FGF17,RGL1,NEUROD1,GNG3,GOLGB1,GPM6A,NPPA,TCF7L2,TCF12,EML4,DDR2,TF,OPCML,USP2,TLL2,PAX6,PCDH8,PDE1A,PDYN,SCRG1,CHGA,ZFYVE9,NRXN1,PMP2,PRRX1,NXPH1,POU3F4,RNF14,PPP2R5C,SNCAIP,CTNND1,MAPK10,PROX1,SYTL2,PHYHIP,LRRTM3,PMEPA1,PTHLH,ELMO1,PRDM2,LRP8,RGMA,PTPRO,SV2A,NAV2,SLC17A6,DSCAM,RET,RFX4,RLBP1,LMO1,ELAVL4,BSCL2" Gene Family 593 Fibronectin type III domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 2.24E-09 6.78E-07 6.78E-07 4.27E-06 23 161 "MAG,DSCAML1,LRRC4C,IGSF9B,PALLD,MYBPC1,NFASC,NCAM1,KIRREL3,ROBO3,UNC5D,CNTN2,LRIT2,OPCML,IGFN1,JAM2,NEGR1,CNTN1,CADM2,PTPRD,NTM,DSCAM,L1CAM" Gene Family 555 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 1.03E-08 3.12E-06 1.56E-06 9.81E-06 22 160 "DSCAML1,ASTN1,IGSF9B,PHYHIPL,MYBPC1,NFASC,NCAM1,ASTN2,ROBO3,CNTN2,TIE1,TNR,IGFN1,FNDC5,FLRT1,CNTN1,CSF3R,PTPRD,PTPRO,PTPRZ1,DSCAM,L1CAM" Gene Family 1179 Apolipoproteins|Sushi domain containing genenames.org 2.17E-07 6.59E-05 1.84E-05 1.16E-04 12 57 "CSMD2,CSMD3,SELL,BCAN,GABBR1,SEZ6L,HPR,VCAN,NCAN,MASP1,SUSD4,SEZ6" Gene Family 682 Zinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors genenames.org 2.42E-07 7.35E-05 1.84E-05 1.16E-04 23 206 "RTKN,PLEKHG5,RASA3,ITSN1,DOCK10,DGKD,CADPS,KIF1B,PHLDB1,ARHGEF7,PSD3,PLEKHB1,ARHGAP22,ANLN,VAV2,OSBPL3,ARHGEF4,PSD,DNM2,PLEKHB2,RASGRF1,ARHGAP12,PLEKHO1" Gene Family 904 Calcium voltage-gated channel subunits|Membrane associated guanylate kinases genenames.org 1.06E-06 3.21E-04 6.42E-05 4.04E-04 8 26 "MAGI3,CACNB2,TJP1,MAGI1,TJP2,MAGI2,DLG2,DLG3" Gene Family 590 Receptor Tyrosine Kinases|CD molecules|V-set domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 2.20E-05 6.66E-03 1.05E-03 6.62E-03 17 163 "ADORA3,SCN4B,MOG,BCAN,IGSF9B,SCN3B,CADM3,VSTM2A,IGSF21,HAPLN2,JAM2,HEPACAM,CADM1,VCAN,NCAN,SIRPA,CADM2" Gene Family 694 Protein phosphatase 1 regulatory subunits genenames.org 2.43E-05 7.36E-03 1.05E-03 6.62E-03 18 181 "MAPT,RYR1,SFPQ,APC,SLC7A14,AHCYL1,BCL2L2,PCDH11X,WWC1,KCNK10,TNS1,PHACTR3,DZIP3,SYTL2,KCNA6,DLG2,DLG3,SH3GLB1" Gene Family 1220 Membrane associated guanylate kinases|PDZ domain containing genenames.org 3.40E-05 1.03E-02 1.18E-03 7.41E-03 16 152 "LRRC7,PDZD4,APBA2,MAGI3,SHANK2,ERBIN,TJP1,MAGI1,TJP2,MAGI2,PARD6A,SNX27,DLG2,DLG3,GOPC,USH1C" Gene Family 274 Potassium voltage-gated channels genenames.org 3.50E-05 1.06E-02 1.18E-03 7.41E-03 8 40 "KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNQ2" Coexpression 18223198-TableS3 Human Brain_Chen-Plotkin08_747genes GeneSigDB 3.32E-40 3.37E-36 3.37E-36 3.30E-35 106 594 "EPS8,RTN3,ACTN2,RTN1,ADORA3,TUBB4A,NLGN4X,ACTL6B,FGR,HPCAL4,SELL,AMPH,ITSN1,PKP4,SH3GL2,APBA2,GAS7,DGKZ,CLSTN1,AQP4,ZNF365,RPH3A,PKNOX2,SLC8A2,SHANK2,ASCL1,SLCO1A2,TAGLN3,BRINP2,SNAP25,SNCB,ATP1A2,SCN3B,MYT1L,GAD2,NMNAT2,ARPP21,ADGRB2,NAP1L2,FXYD6,ERBIN,NCDN,NELL1,GLS,GNAS,GNG3,DDR1,TCF12,NRGN,CAMK2A,TMEM151B,PSD3,GRIA1,GRIN1,OPCML,TGFBR3,INA,TJP1,CDC42,TNS1,DCLK1,SEZ6L,PCSK2,ACOT7,CHGA,HPCA,GDAP1L1,NRXN1,CAMKV,TJP2,SULT4A1,CABP1,PPP3CB,MICAL2,VCAN,DZIP3,CALY,PRKCZ,KIAA0513,PHYHIP,TUBB2B,SYNC,PRDM2,STMN4,PTPRO,KCND3,SV2A,SRGAP3,AK5,KCNJ4,KCNK1,KCNQ2,DLG2,DLG3,DPP6,RAP1GAP,SUSD4,DTNA,L1CAM,CAMK1G,USH1C,RGS7,EEF1A2,SSPN,ELAVL4,BSCL2" Coexpression M10371 "Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells, as identified by ChIP on chip." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.03E-39 2.06E-35 1.03E-35 1.01E-34 147 1117 "TTYH1,C1orf194,MAP6,RIMKLA,ASIC1,MAPT,RCSD1,IL17D,FAM43B,CSMD2,KCNIP2,CSMD3,ADARB2,DSCAML1,SLITRK1,RXRG,SORCS1,AMER2,SCN4B,ACTL6B,ELMOD1,SLC30A10,HPCAL4,FOXG1,AMPH,SH3GL2,PPM1E,SLITRK3,BCAN,SLC1A2,PKNOX2,MT3,DACH2,ASCL1,PDE8B,LGI3,SLIT1,DDX25,BRINP2,SORCS3,ASTN1,TMEM151A,ATP1A3,PHYHIPL,ILDR2,GAD2,B4GALNT1,NKX6-2,TTLL9,ADAM15,ADGRB2,DNER,NCAM1,COLGALT2,NELL1,KIRREL3,PHLDB1,NEUROD1,NFIA,ARHGEF7,ABCC8,ASTN2,DCLK2,NKX2-2,ROBO3,CDK5R2,MMD2,CNTN2,ADGRL3,CACNA1A,PRUNE2,WSCD1,GPM6B,CACNA1E,PRLHR,GPR26,NRGN,AZIN2,SYT6,GRIA2,GRID1,GRIK3,GRIN1,GPR88,INA,GUCY1A1,NEURL1,PAX6,TNFRSF1B,REPS2,IGSF21,PADI2,C1orf94,PCDH8,DCLK1,PCSK2,CIART,FNDC5,HPSE2,TMEFF2,TLX1,NRXN1,NEGR1,ST8SIA5,SLC25A27,COL9A2,CNRIP1,MFSD4A,POU3F2,POU3F4,CRMP1,SNCAIP,FEZ1,CHD5,RIMS4,CTNND2,HES5,BRINP3,ZBTB16,DPYSL5,CA10,PLPPR1,PTHLH,KCNA1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK2,KCNMA1,NAV2,HS3ST4,SLC17A6,DPP6,SUSD4,RASGRF1,CRTAC1,RFX4,RGS10,TTLL7,EFNA3,LMO1,ELAVL3,EN2,OLIG2,SEZ6" Coexpression M2019 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.96E-38 3.00E-34 9.72E-35 9.53E-34 103 589 "TTYH1,RIMKLA,ACHE,PAQR6,ACTN2,DSCAML1,TUBB4A,DISP3,FGF14,ACTL6B,C1QTNF4,ASIC4,GOLGA7B,FOXG1,APBA2,SLITRK3,BCAN,SHTN1,SLC7A14,SLC8A2,CSPG5,SLIT1,DLL3,SORCS3,ASTN1,SNAP25,SNCB,NRG3,ATP1A3,ATP2B2,SCN3B,SOX1,CADM3,NKX6-2,LHFPL4,TTC9B,CPLX2,RAP1GAP2,FGF17,NELL1,NEUROD1,ABCC8,LUZP2,NKX2-2,CDK5R2,CNTN2,WSCD1,ACSL6,CACNA1E,VWC2,DIRAS1,GPR26,TMEM151B,VSTM2A,BRSK2,GRIA2,GRID1,GRIK3,CCKBR,LEFTY2,IGSF21,PADI2,PCDH8,CDH8,SEZ6L,PRMT8,FNDC5,LRTM2,CHGA,CHRNB2,TLX1,NRXN2,PIK3CD,NECAB2,PACSIN1,NXPH1,POU3F2,PHACTR3,PLPP4,PRKCZ,SLC45A1,HES5,PSD,DNAJC6,CA10,KCNA2,CDH20,KCNC1,KCND3,KCNH1,NTM,KCNJ10,KCNQ2,OLIG1,SLC17A6,DSCAM,CRTAC1,ST8SIA3,RFX4,EEF1A2,CBLN2,OLIG2,RASGRP2" Coexpression 19185848-TableS1 Mouse StemCell_Read09_438genes GeneSigDB 3.84E-38 3.89E-34 9.72E-35 9.53E-34 74 299 "ACER3,ASIC1,MAPT,APC2,ATAT1,KLHL32,RTN1,TUBB4A,SCN3A,SEMA6A,ACTL6B,SGIP1,CNIH2,PPM1E,APBB1,APC,SORBS1,YPEL4,CADPS,SPHKAP,SNAP25,GABBR1,MYT1L,TNIK,KIF21B,CADM3,JPH4,ARPP21,KIF1B,DNER,NAP1L2,NFASC,GPR162,NEUROD1,SEPT3,ARHGEF7,NHLH1,GNG3,CNTN2,ANO4,GPM6A,BRSK2,GRIA4,GRIK2,INA,CELF3,CDC42,DCLK1,TPM3,MAGI1,TUB,NRXN1,CNTN1,CELF5,PRKCZ,MAPK10,DNAJC6,CADM2,ELMO1,STMN4,SV2A,SRGAP3,RABGAP1L,KCNK2,KCNQ2,NKAIN1,PID1,SLC17A6,DTNA,PAK5,L1CAM,ATL1,ELAVL4,RCAN2" Coexpression 19621087-Table1e Mouse EmbryonicStemCell_Abranches09_919genes GeneSigDB 9.01E-34 9.14E-30 1.83E-30 1.79E-29 94 555 "TTYH1,ASIC1,MAPT,ACHE,APC2,MEG3,ATAT1,CSMD2,SNX32,SCN3A,ACTL6B,SGIP1,CNIH2,ITSN1,DOCK10,APC,NTNG1,SYBU,ST8SIA1,YPEL4,CCDC88A,SCMH1,ASCL1,TAGLN3,DLL3,SNAP25,GABBR1,SCN3B,MYT1L,TNIK,SOX5,KIF21B,DNER,NPAS3,DCAF5,GFRA1,FAM168A,NFIA,MLC1,ARHGEF7,GLS,PCDH11X,NHLH1,OS9,SYT4,ROBO3,CAMTA1,CNTN2,ADGRL3,GPM6B,ACSL6,HAP1,GRIA2,GRIK2,CDC42,IGSF21,PCDH9,DCLK1,MAGI1,ADGRG1,CHRNB2,TMEFF2,JAM2,NRXN1,CNTN1,SLC25A27,PRRX1,SLC36A4,POU3F2,POU3F4,NKAIN4,SDC3,CTNND2,MAPK10,TUBB2B,CADM2,HP1BP3,KCNC1,PTPRO,KCND3,SRGAP3,NTM,KCNK2,KCNQ2,OLIG1,SLC17A6,PAK5,L1CAM,RGS7,TTLL7,ELAVL3,ELAVL4,OLIG2,LRRC23" Coexpression M2115 Genes correlated with proneural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.82E-33 3.87E-29 6.45E-30 6.32E-29 54 177 "DPF1,TTYH1,ABAT,MAPT,ATAT1,KLRC4,CDC7,SCN3A,LRRTM4,C1orf61,PPM1E,BCAN,ASCL1,SCG3,CSPG5,DLL3,SORCS3,ATP1A3,KIF21B,SOX10,FXYD6,NCAM1,CLASP2,PCDH11X,NKX2-2,GNG4,CAMSAP2,ADGRL3,GPM6A,GPR17,GRIA2,CRB1,P2RX7,CELF3,SEZ6L,DUSP26,NLGN3,NRXN1,NRXN2,FLRT1,CNTN1,CRMP1,RBPJ,CA10,STMN4,SRGAP3,NKAIN1,KLRC3,DPP6,PAK5,ZNF248,SEC61A2,OLIG2,EPB41" Coexpression M9898 Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [GeneID=23512] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.43E-30 3.48E-26 4.97E-27 4.87E-26 126 1038 "TTYH1,EPS8,C1orf194,MAP6,RIMKLA,MAPT,RCSD1,FAM43B,WLS,CSMD3,ADARB2,DSCAML1,SLITRK1,RXRG,SORCS1,AMER2,GPR158,SCN4B,ELMOD1,SLC30A10,HPCAL4,FOXG1,PPM1E,GAS7,SLITRK3,ST8SIA1,SLC1A2,ZNF365,PKNOX2,SLC8A3,DACH2,ASCL1,PDE8B,LGI3,SLIT1,BRINP2,SORCS3,ASTN1,PHYHIPL,MEGF11,SOX1,CADM3,SOX10,ILDR2,GAD2,B4GALNT1,NKX6-2,ADGRB2,DNER,NCAM1,C11orf87,COLGALT2,ALDH1L1,GFRA1,NELL1,KIRREL3,PHLDB1,NEUROD1,NFIA,ARHGEF7,ABCC8,PCDH11X,ASTN2,DCLK2,NKX2-2,GNAS,ROBO3,CDK5R2,ADGRL3,CACNA1A,GPM6B,CACNA1E,PRLHR,HAP1,SYT6,GRIA2,GRID1,GRIK3,GPR88,INA,GUCY1A2,GUCY1A1,TLL2,CELF3,PAX6,TNFRSF1B,REPS2,IGSF21,PCDH8,PRMT8,HPSE2,TMEFF2,TLX1,COL9A2,CNRIP1,MFSD4A,POU3F4,CRMP1,FEZ1,CTNND2,BRINP3,ZBTB16,DPYSL5,CA10,PLPPR1,PTHLH,KCNA1,PLPPR4,KCND3,KCNH1,KCNK2,KCNMA1,NAV2,HS3ST4,OLIG1,TMEM255A,DPP6,SUSD4,RASGRF1,DBX2,CRTAC1,RGS10,EFNA3,ELAVL3,EN2,OLIG2" Coexpression 19621087-Table1d Mouse EmbryonicStemCell_Abranches09_1170genes GeneSigDB 5.13E-25 5.20E-21 6.50E-22 6.37E-21 89 651 "ABAT,RTN3,ADGRV1,EYA1,ATAT1,WLS,RTKN,CLIP1,RTN1,WAC,FABP7,SORCS1,AMER2,FOXG1,SOX6,ANK2,RASA3,ITSN1,PPM1E,APBA2,SLC1A2,DACH2,CADPS,ASCL1,ASTN1,SMARCE1,TMEM108,FYN,ILDR2,KIF1B,ADGRB2,NPAS3,NFASC,NCAM1,ERBIN,DCAF5,SEPT3,GNAS,ADGRL3,GPM6A,GPM6B,ZEB1,TCF12,PTBP2,BRSK2,MFSD2A,FBXL16,PAX6,PCDH8,DCLK1,MAGI1,CADM1,SEMA5B,NEGR1,FAM181B,PRRX1,NSD2,FAT3,POU3F4,SNCAIP,FEZ1,ATRNL1,NCAN,DOCK7,DZIP3,FMN2,CTNND2,MAPK10,HES5,PROX1,TOX,DPYSL5,JAKMIP2,LRP8,SHD,KCNA1,PTPRD,PTPRZ1,SRGAP3,TMCC2,ARNT2,NKAIN1,RFX4,PHC2,VANGL2,FGFBP3,ELAVL4,EN2,PLEKHO1" Coexpression M1884 Genes up-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.52E-23 5.60E-19 6.22E-20 6.10E-19 130 1305 "DPF1,MAG,ABAT,MAP6,MAPT,ACHE,SYT9,ADAR,RTN1,ADCYAP1R1,CDC7,ADORA3,HOGA1,AGT,SCN3A,LRRC7,FGF14,FGR,HPCAL4,MOBP,FOXG1,FOXM1,SELL,ANK3,SH3GL2,APBA2,APBB1,APC,GAS7,DGKZ,GPAM,BCAN,NLGN1,ST3GAL3,ST8SIA1,SLC1A2,SLC1A6,MADD,SLC6A9,SLC8A2,SLC8A3,MT3,SCG3,CSPG5,ARFGAP1,DLL3,ASPH,B3GAT1,SNAP25,ATP1A3,ATP2B2,GABBR1,MYT1L,SOX10,MYH7,CPLX2,NDUFA5,GFAP,FGF17,GJB1,ABCC8,C1QC,GNAS,CNTN2,CACNA1A,DDR1,NPPA,CLEC9A,GPR19,NRGN,HAP1,CAMK2A,CAMK2G,GRIA1,GRID1,GRIK4,GRIN1,GRM3,TF,TGFBR3,INA,CDK11B,TNR,PADI2,CDH8,PDE2A,PDE4B,ACOT7,PFKFB3,CHRM1,CHRM4,CHRNB2,PHKG1,NLGN3,DLGAP3,CADM1,CAMKV,PIK3CD,CNTN1,POU3F2,FEZ1,NCAN,PRKCG,PRKCZ,CTNND2,HES5,MASP1,SIRPA,KCNA1,KCNA2,KCNA4,KCNA6,PTPRE,KCND3,KCNJ4,KCNJ9,KCNJ10,KCNJ11,KCNK1,KCNN3,DLG2,PYGM,DPP6,RALGDS,L1CAM,ABCC9,RET,EEF1A2,ABI2,ELAVL4" Coexpression 15902281-TableS1b Human Leukemia_Schoch05_1693genes GeneSigDB 7.07E-23 7.17E-19 7.17E-20 7.03E-19 94 767 "PRR5L,LGR4,RTN3,MRVI1,GRAMD1B,C1QTNF4,BBOX1,SOX6,ASRGL1,FOLH1,USP28,PPFIA1,APBB1,DGKZ,API5,PAAF1,SLC1A2,MADD,ARFGAP2,SHANK2,SLN,DDX25,B3GAT1,IGSF9B,ATM,DKK3,SCN3B,STARD10,FXYD6,NCAM1,NELL1,PHLDB1,GANAB,FAM168A,ABCC8,ROBO3,GNG3,NRGN,NUMA1,BRSK2,GRIA4,GRIK4,ADAMTS8,OPCML,CCKBR,USP2,GUCY1A2,ZFP91,CD81,PAX6,HPS5,PC,PTGDR2,HRH3,PDE2A,PDE3B,TMPRSS5,CHRM1,PLEKHB1,TUB,MS4A7,CHRM4,ZBED5,SLC22A6,CADM1,NRXN2,FADS2,FLRT1,BEST1,SF1,TENM4,FEZ1,MICAL2,CTNND1,ZBTB16,SYTL2,PSMD13,KCNA4,KCNC1,NTM,KCNJ11,NAV2,DLG2,PYGM,RAB3IL1,SLC17A6,USH1C,SIDT2,LMO1,VWA5A,ROM1,BSCL2,RASGRP2,UEVLD" Coexpression M2369 Genes down-regulated during differentiation of Oli-Neu cells (oligodendroglial precursor) in response to PD174265 [PubChem=4709]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.10E-22 1.12E-18 1.02E-19 9.95E-19 115 1080 "TTYH1,EPS8,SERPINA3,ZFYVE27,MAP6,ASIC1,MAPT,MBP,ATAT1,LDLRAD3,WLS,DSCAML1,ADD3,WAC,SNX30,TUBB4A,ANK3,CNIH2,PKP4,APBA2,SESN3,GAS7,SORBS1,LRRC4C,ST8SIA1,BCAS1,ZNF365,ARHGAP5,MT3,CCDC88A,ASTN1,TMEM108,TMEM151A,FYN,PHYHIPL,MIR4697HG,KIF1B,DNER,NASP,NFASC,ERBIN,RCOR2,KIRREL3,PHLDB1,ACSBG1,SYT4,KAZN,CAMSAP2,MYRF,BTRC,ADGRL3,WSCD1,DDR1,TCF7L2,GPR17,TCF12,GRIA2,GRIA4,RFFL,ATP13A2,OMG,TGFBR3,CD81,REPS2,TNR,PADI2,TNS1,CDH10,DCLK1,PDE4B,ZMYND8,TMPRSS5,CA14,TMEFF2,JAM2,CADM1,SEMA5B,NEGR1,FAM181B,PLXNB3,IFFO1,NSD2,ACBD5,BTBD17,CNRIP1,NCAN,DOCK7,FMN2,ACY3,PLPPR5,CADM2,KCNA1,CDH20,KCNA6,PTPRE,PTPRZ1,SV2A,RABGAP1L,TMCC2,NAV2,PEX5,NKAIN1,RALGDS,ABI1,DSCAM,FAM13C,DTNA,RTN4,RFX5,ATL1,RBM12,VWA5A,ELAVL3,EPB41L1,EPB41L2" Coexpression M1954 Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.62E-19 2.66E-15 2.21E-16 2.17E-15 63 434 "ASIC1,ACHE,FAM43B,DRAXIN,SCN4B,DISP3,C1QTNF4,ASIC4,SLC30A10,ANK1,SLITRK3,BCAN,STK32C,SLC8A2,LGI3,SLIT1,DLL3,NRG3,PHYHIPL,ATP2B2,NKX6-2,TTC9B,ADGRB2,NPAS3,NELL1,NEUROD1,ABCC8,CNTN2,WSCD1,PRLHR,TMEM151B,SYT6,BRSK2,GRIA2,GRID1,SHISA7,CCKBR,PTPN5,IGSF21,SEZ6L,PRMT8,FNDC5,NTSR2,LRTM2,CHRNB2,NRXN2,COL9A2,NECAB2,PACSIN1,RIMS4,HES5,ZBTB16,PLPPR5,KCNA2,KCND3,KCNH1,AK5,KCNJ4,KCNMA1,KCNQ2,DSCAM,L1CAM,LMO1" Coexpression 18308945-Table3 Human StemCell_Huang08_60genes_NSCs GeneSigDB 4.45E-19 4.51E-15 3.44E-16 3.37E-15 23 52 "FABP7,AMER2,FOXG1,ANK2,AQP4,SLC1A2,ASCL1,CSPG5,ATP1A2,DNER,COLGALT2,GPM6A,GPM6B,GRIA2,PAX6,DCLK1,NRXN1,FAT3,NCAN,CTNND2,TUBB2B,PTPRZ1,RFX4" Coexpression M8448 Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [GeneID=23512] and EED [GeneID=8726] Polycomb proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.75E-19 4.82E-15 3.44E-16 3.37E-15 79 652 "TTYH1,C1orf194,RIMKLA,MAPT,FAM43B,CSMD3,ADARB2,DSCAML1,SLITRK1,SORCS1,SCN4B,ELMOD1,HPCAL4,FOXG1,PPM1E,SLITRK3,SLC1A2,PKNOX2,DACH2,ASCL1,SLIT1,BRINP2,SORCS3,ASTN1,ILDR2,GAD2,B4GALNT1,NKX6-2,NCAM1,COLGALT2,NELL1,KIRREL3,NEUROD1,ABCC8,ASTN2,DCLK2,NKX2-2,ROBO3,CDK5R2,ADGRL3,GPM6B,CACNA1E,PRLHR,GRIA2,GRID1,GRIK3,GPR88,INA,GUCY1A1,PAX6,REPS2,IGSF21,PCDH8,HPSE2,TMEFF2,TLX1,COL9A2,CNRIP1,POU3F4,FEZ1,CTNND2,BRINP3,ZBTB16,CA10,PLPPR1,PTHLH,KCNA1,KCND3,KCNH1,KCNK2,KCNMA1,NAV2,SUSD4,RASGRF1,CRTAC1,RGS10,EFNA3,EN2,OLIG2" Coexpression M14594 Genes with copy number losses in primary neuroblastoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.19E-19 6.28E-15 4.18E-16 4.10E-15 89 799 "ZFYVE27,ARID1A,ADD3,CHST15,FGR,GOLGA7B,HPCAL4,SFPQ,ASRGL1,USP28,GPAM,ZCCHC17,SORBS1,ST3GAL3,JAKMIP3,PAAF1,CLSTN1,MIER1,RUFY2,SCMH1,GPR153,ATM,EIF4G3,USP33,WDTC1,ZSWIM8,EMC1,KIF1B,ADGRB2,NASP,MIR100HG,CLASP2,NCDN,FAM168A,NFIA,CAMTA1,BTRC,TMEM136,NRDC,CAMK2G,NUMA1,CROCCP2,GRIA4,GRID1,ATP13A2,TMEM25,INA,TNFRSF1B,CDC42,FNDC5,ACOT7,CADM1,CCSER2,MEAF6,BTF3L4,COL9A2,SPATA6,NSD2,CRMP1,TENM4,PPP3CB,FEZ1,ATRNL1,CHD5,RBPJ,PRKACB,DOCK7,PRKCZ,PUM1,EDRF1,RIMS3,SYNC,PTAFR,DNAJC6,PRDM2,HP1BP3,NKAIN1,BEND5,BSDC1,ZYG11B,ARHGEF10L,PHC2,TTLL7,RNF220,SIDT2,SH3GLB1,FGFBP3,ELAVL4,EPB41" Coexpression M17728 Genes down-regulated in brain from patients with Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.99E-18 5.06E-14 3.16E-15 3.10E-14 115 1237 "RABEPK,ABAT,RPL38,ACHE,RTN3,MEG3,CLIP1,RTN1,ADCY2,FABP7,SCN3A,ACTL6B,FHL1,HPCAL4,FOXG1,SFPQ,ANK3,ANXA7,APBA2,APC,BCAN,TACC2,PKNOX2,SHANK2,CADPS,SCG3,CSPG5,TAGLN3,ASPH,SORCS3,ASTN1,SNAP25,ATP1A2,ATP2B2,GABBR1,SCN3B,USP33,SON,MYT1L,B3GALT2,CAB39,GAD2,NMNAT2,B4GALNT1,KIF1B,ADGRB2,NAP1L2,FXYD6,CLASP2,NDUFA5,NELL1,NEUROD1,SLCO1C1,GLS,VAMP1,GNAS,GNG3,ADGRL3,GPM6A,CACNB2,NRGN,CAMK2A,PSD3,GRIA1,GRIA2,ATP13A2,OMG,INA,CDC42,CDH8,CDH10,SEZ6L,PCSK2,PDE2A,PDE4B,ACOT7,SCRG1,CHGA,HNRNPK,HPCA,NRXN1,DNAJC12,SULT4A1,CABP1,CRMP1,RNF14,PPP2R5C,PPP3CB,NCAN,ARHGEF4,MAPK10,NOS1AP,TOX,TOMM20,DNAJC6,ELMO1,LRP8,COPS7A,PTPRE,SV2A,AK5,ARNT2,KCNK1,KCNQ2,DLG2,KIF2A,RTN4,L1CAM,CAMK1G,RFX5,RGS7,SEC61A2,ELAVL4,BSCL2,RCAN2" Coexpression M7617 Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [GeneID=8726] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-17 1.87E-13 1.10E-14 1.08E-13 103 1062 "TTYH1,EPS8,C1orf194,RIMKLA,MAPT,FAM43B,ARID1A,WLS,CSMD3,ADARB2,DSCAML1,SLITRK1,CDC7,SORCS1,SCN4B,ELMOD1,HPCAL4,FOXG1,PPM1E,SLITRK3,ST8SIA1,SLC1A2,ZNF365,PKNOX2,SLC8A3,DACH2,ASCL1,SLIT1,BRINP2,SORCS3,ASTN1,MEGF11,SOX1,SOX5,ILDR2,GAD2,B4GALNT1,NKX6-2,NCAM1,C11orf87,COLGALT2,GFRA1,NELL1,KIRREL3,NEUROD1,ABCC8,ASTN2,DCLK2,NKX2-2,ROBO3,CDK5R2,MMD2,ADGRL3,GPM6B,CACNA1E,PRLHR,HAP1,GRIA2,GRID1,GRIK3,GPR88,GRM3,INA,GUCY1A1,NEURL1,PAX6,REPS2,IGSF21,PCDH8,DCLK1,HPSE2,TMEFF2,TLX1,ST8SIA5,COL9A2,CNRIP1,POU3F2,POU3F4,RGS6,FEZ1,CTNND2,BRINP3,ZBTB16,CA10,PLPPR1,PTHLH,MAGI2,KCNA1,KCND3,KCNH1,KCNK2,KCNMA1,NAV2,OLIG1,SUSD4,RASGRF1,CRTAC1,JMJD1C,RGS10,EFNA3,LMO1,EN2,OLIG2" Coexpression 15374961-TableS2 Human Brain_Freije04_595genes GeneSigDB 9.15E-17 9.27E-13 5.15E-14 5.05E-13 62 474 "SERPINA3,MAPT,APC2,MEG3,NDRG2,ADCY2,DSCAML1,GALNT13,HHATL,AMER2,SCN3A,C1QTNF4,FOXM1,BCAN,SORBS1,PDE8B,SCG3,SPHKAP,DLL3,NRG3,ATP2B2,JPH4,ARPP21,TTC9B,CPLX2,NCAM1,STOX1,SMOC1,SYT4,CACNA1E,ZEB1,CRB1,PTPN5,ZDHHC22,DAAM2,REPS2,PDE1A,CHRM1,NEGR1,TJP2,FLRT1,P2RY12,PACSIN1,MFSD4A,CP,NKAIN4,MICAL2,VCAN,NRSN1,TOX,ANKS1B,KCNJ9,KCNN3,DLG2,HS3ST4,KLRC3,CALN1,DTNA,CRTAC1,CBLN2,TMEM100,RCAN2" Coexpression 19605494-TableS2 Mouse Skin_Driskell09_1477genes GeneSigDB 4.64E-16 4.70E-12 2.47E-13 2.43E-12 88 872 "MAG,TTYH1,MAPT,MBP,LGR4,RCSD1,GALNT13,ERMN,CHST15,SCN4B,LRRTM4,FGF1,FGF14,FOXM1,CDC42BPA,ANXA7,NTNG1,CCDC80,SORBS1,NLGN1,SLC8A3,ASPH,TMEM108,PALLD,TNIK,GART,DNER,NCAM1,STOX1,NELL1,RGL1,NFIA,ARHGEF7,PCDH11X,GNAS,MMD2,PSRC1,ADGRL3,GPM6B,BRSK2,GRIA2,GRIK2,P2RX7,ZFP91,REPS2,PCDH9,CDH10,DCLK1,LGI1,MAGI1,PDE1C,PDE2A,ADGRG1,PLEKHB1,DUSP26,SERPINE2,NRXN1,NEGR1,TJP2,VAV2,PLXNB3,CNTN1,PMP2,PRRX1,P2RY12,FAT3,CP,FEZ1,MICAL2,VCAN,ECE2,MASP1,ZBTB16,DNAJC6,CADM2,KCNA1,PTPRD,PTPRZ1,NTM,KCNJ10,ARNT2,NAV2,TMEM255A,BEND5,JMJD1C,RGS10,TTLL7,SSPN" Coexpression 19658189-TableS4 Human EmbryonicStemCell_Xu09_1801genes GeneSigDB 2.05E-15 2.08E-11 1.04E-12 1.02E-11 120 1430 "ACLY,EMID1,MBP,KCNIP2,SLC25A25,CSMD3,F3,ADARB2,RTN1,ADD3,CDC7,TUBB4A,NLGN4X,TESK2,SEMA6A,C1QTNF4,BCAR3,FGR,UNC79,HPCAL4,PDZD4,SOX6,TRIM46,ASRGL1,PPFIA1,SH3GL2,PPM1E,APBA2,SHTN1,SLC1A2,SLC1A6,BCO1,SLC8A2,MT3,SLCO1A2,SLIT1,DLL3,B3GAT1,TMEM108,GABBR1,SOX10,NMNAT2,JPH4,KIF1B,NFASC,RCOR2,RND1,ACSBG1,ABCC8,RHBDL3,SEMA4A,ROBO3,GNG3,GNG4,NODAL,PSRC1,CNTN2,WWC1,GPM6B,B4GALNT4,GPR17,GPR19,DIRAS1,SYT6,BRSK2,AKNA,ADAMTS8,VWCE,CCKBR,FBXL16,INA,TIE1,ZDHHC22,KCNK10,TNFRSF1B,IGSF21,PCDH8,TPD52,TPM4,PDE2A,PDYN,ACOT7,CHGA,JAM2,SERPINE2,NRXN1,CAMKV,SEMA5B,A2ML1,SULT4A1,PLXNB3,MICAL1,COL9A2,SPATA6,ATCAY,PRKCZ,ARHGEF4,HES5,KLK6,TUBB2B,ELMO1,CNIH3,LRP8,RGMA,KCNA1,PTPRE,PTPRZ1,KCNK1,KCNQ2,FAM57B,SLC6A15,RET,RGS7,RGS10,VANGL2,CACNG7,ABI2,OLIG2,EPB41L2,SEZ6" Coexpression M12135 Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.10E-15 8.21E-11 3.91E-12 3.83E-11 33 164 "TTYH1,APC2,ATAT1,MDM4,RTN1,FABP7,LINC00461,FOXG1,CADPS,ASCL1,SCG3,FYN,NAP1L2,GFRA1,NEUROD1,RHBDL3,GPM6B,NUDT21,BRSK2,INA,PRMT8,ADGRG1,JAM2,SPATA6,POU3F4,NCAN,FMN2,MAPK10,KIAA0408,JAKMIP2,SLC17A6,ELAVL3,ELAVL4" Coexpression 19168792-TableS3 Human Leukemia_Figueroa09_1035genes GeneSigDB 8.82E-15 8.94E-11 4.06E-12 3.98E-11 79 774 "MAP6,SORCS1,AMER2,FOXG1,CDC42BPA,SLITRK3,LRRC4C,AQP4,SLC1A6,SLC8A3,CADPS,SCG3,SORCS3,ADGRA1,DKK3,MYH7,B4GALNT1,SALL3,LHFPL4,KIF1B,CPLX2,NPAS3,GFRA1,FGF17,NELL1,NEUROD1,ARHGEF7,RHBDL3,NKX2-2,CDK5R2,CACNA1A,PRUNE2,CACNA1E,VWC2,PRLHR,GPR26,SYT6,VSTM2A,GRIA2,GRM3,TJP1,IGSF21,PCDH8,CDH8,MAGI1,PDYN,HPSE2,CA14,TUB,TMEFF2,DLGAP3,GDAP1L1,PRRX1,NXPH1,POU3F2,POU3F4,SNCAIP,RGS6,FEZ1,CHD5,VCAN,PRKCZ,PROX1,BRINP3,SPIRE1,CA10,PTHLH,RGMA,KCNA4,PTPRO,PTPRZ1,KCNJ9,RAB3IL1,ATN1,RASGRF1,DBX2,SLC6A15,ELAVL3,UEVLD" Coexpression M1941 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation at K4 (H3K4me2) and trimethylation at K27 (H3K27me3) in brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.21E-14 1.23E-10 5.34E-12 5.24E-11 97 1069 "ABAT,PRR5L,RCSD1,ADGRV1,EYA1,NDRG2,F3,SLC44A5,SCN4B,C1QTNF4,BCAR3,SLC30A10,BCAN,SFMBT2,ASCL1,DLL3,TMEM108,NRG3,MEGF11,SOX1,GAD2,NKX6-2,SALL3,ADGRB2,FXYD6,RAP1GAP2,SMOC1,ERBIN,GFRA1,NELL1,NEUROD1,POPDC3,NKX2-2,GNAS,NODAL,CNTN2,TBX15,FAM69C,VWC2,PRLHR,TCF7L2,GPR26,TMEM151B,SYT6,GRIK3,ADAMTS8,GPR88,CCKBR,PTPN5,MFSD2A,INA,TLL2,PAX6,IGSF21,PCDH8,HRH3,SEZ6L,NTSR2,ANO5,CHRNB2,SERPINE2,SEMA5B,ANLN,FAM181B,VAV2,POU3F2,SNCAIP,TENM4,RGS6,PLPP4,PLD5,PRKCZ,PROX1,DPYSL5,TUBB2B,CA10,PTHLH,CNIH3,PTPRO,KCNH1,KCNJ4,KCNJ10,CCDC3,KCNQ2,OLIG1,DPP6,RASGRF1,DBX2,CRTAC1,RET,RGS10,RNF220,LMO1,CBLN2,EN2,OLIG2,EPB41L1" Coexpression 19168792-TableS2 Human Leukemia_Figueroa09_567genes GeneSigDB 1.74E-14 1.77E-10 7.37E-12 7.22E-11 54 419 "MAP6,MBP,ACTN2,SORCS1,AMER2,SEMA6A,FOXG1,CDC42BPA,STK32C,CADPS,CSPG5,SORCS3,ADGRA1,SNAP25,DKK3,SCN3B,SALL3,LHFPL4,TTLL9,KIF1B,NPAS3,GFRA1,NELL1,NEUROD1,ACSBG1,NKX2-2,GNAS,CACNA1A,CACNA1E,VWC2,GRIK2,GRIK3,GUCY1A2,TJP1,IGSF21,PCDH8,CDH8,MAGI1,HPSE2,CHRNB2,TMEFF2,PRRX1,POU3F2,PRKCZ,BRINP3,SPIRE1,CA10,PTHLH,KCNJ9,RASGRF1,DBX2,SLC6A15,RET,ELAVL3" Coexpression M2892 Genes up-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.21E-14 4.26E-10 1.71E-11 1.67E-10 30 143 "RTN1,TUBB4A,HPCAL4,ANK2,ANK3,SORBS1,AQP4,NSG2,SCG3,SNAP25,ATP1A2,NMNAT2,ARPP21,NAP1L2,LMO3,WSCD1,GPM6A,GPR19,GRIA2,GRIK2,PCDH9,CHGA,NRXN1,PMP2,CP,AK5,CAB39L,SLC6A15,TMEM100,RCAN2" Coexpression 17880687-TableS3 Human Embryo_Heim07_1515genes GeneSigDB 9.32E-14 9.45E-10 3.64E-11 3.56E-10 89 971 "TMEM74,LGR4,CSMD2,RTKN,NDRG2,CLIP1,FABP7,AMER2,NLGN4X,PDZD4,ASRGL1,RASA3,APBA2,GAS7,TACC2,SLC1A6,URGCP,SHANK2,TAGLN3,DDX25,B3GAT1,TMEM108,GABBR1,KIF21B,CADM3,LHFPL4,CPLX2,FXYD6,NASP,NCAM1,LMO3,RND1,SEPT3,NFIA,RHBDL3,PCDH11X,KAZN,GNG3,GNG4,NODAL,CNTN2,KLHL4,PRUNE2,WSCD1,GPM6B,TCF12,PTBP2,AKNA,RFFL,CCKBR,LEFTY2,INA,TLL2,DCLK1,TPM4,ZMYND8,FNDC5,PLEKHB1,TJP2,CCDC136,MICAL1,SF1,TENM4,FEZ1,RBPJ,PLPP4,TOX,RIMS3,SYTL2,LRP8,SHD,MAGI2,PTPRO,PTPRZ1,NTM,KCNJ4,RABGAP1L,KCNQ2,OLIG1,DPP6,RTN4,L1CAM,RET,ST8SIA3,EPB41,EPB41L1,EPB41L2,RASGRP2,BAALC" Coexpression M16478 Genes down-regulated in medulloblastoma tumors from animals with inactivating mutations of one copy of PTCH1 or SUFU [GeneID=5727;51684] in conjunction with TP53 [GeneID=7157] loss. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.85E-13 6.95E-09 2.57E-10 2.52E-09 22 83 "CEND1,MEG3,C1QTNF4,ELMOD1,CNIH2,SLC1A6,ASPH,ATP2B2,NCAM1,C11orf87,GRIA1,GRM3,GUCY1A1,DCLK1,PRKCG,NRSN1,MASP1,LRP8,NTM,KCNK1,SLC4A10,RCAN2" Coexpression M2116 Genes correlated with neural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.34E-13 8.46E-09 3.02E-10 2.96E-09 27 129 "MBP,NDRG2,ADD3,SLC30A10,HPCAL4,ANXA7,SH3GL2,BCAS1,SHTN1,SLCO1A2,USP33,MYBPC1,RND1,POPDC3,CAMK2G,GRM3,REPS2,CDC42,TPM3,NTSR2,HPCA,BEST1,ETNPPL,ATRNL1,ANKS1B,KCNK1,RERGL" Coexpression 19861896-SuppTable1 Human Brain_Castells09_424gebes GeneSigDB 2.04E-12 2.07E-08 7.13E-10 6.99E-09 47 373 "SERPINA3,APC2,ACTN2,FABP7,TUBB4A,AGT,SCN3A,FOXM1,RASA3,GAS7,BCAS1,SLC1A2,MT3,GPR153,SCG3,ASTN1,FYN,NEK6,NCAM1,GFAP,PSRC1,GPM6A,GPM6B,GPR17,PSD3,GRIK3,TGFBR3,MFSD2A,GUCY1A1,PDE4B,PLEKHB1,JAM2,CNTN1,PRKACB,CTNND2,DNAJC6,ELMO1,PRDM2,PTPRZ1,TMCC2,KCNQ2,RALGDS,DSCAM,LPAR6,RAVER2,ELAVL4,BAALC" Coexpression M7184 Genes up-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.74E-12 2.78E-08 9.26E-10 9.08E-09 12 21 "CSPG5,DLL3,ADGRB2,ADGRL3,GRIA2,ADGRG1,CRMP1,HES5,PTPRZ1,OLIG1,VANGL2,OLIG2" Coexpression M2110 Genes whose expression significantly and positively correlated with the density of CALB1-positive [GeneID=793] GABAergic interneurons in the BA9 brain region across all subjects with psychiatric disorders. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.61E-12 8.73E-08 2.82E-09 2.76E-08 58 548 "MAPT,ADAR,RTN1,FHL1,FOXG1,AMPH,ANXA7,CLSTN1,ZNF365,MADD,NSG2,SNAP25,SNCB,ATP1A3,NMNAT2,ADGRB2,LMO3,NDUFA5,NCDN,NELL1,GNAS,DDHD2,CAMSAP2,CACNA1A,PRUNE2,GPM6A,NRGN,CAMK2G,GRIA2,OMG,OPCML,INA,PCDH8,DCLK1,PDE2A,ACOT7,CHGA,HNRNPK,HPCA,NRXN1,NECAB2,CRMP1,ATRNL1,PRKACB,PUM1,KIAA0513,TOMM20,ELMO1,COPS7A,CEP170,KCNK1,DLG3,DPP6,RTN4,SLC6A15,CAMK1G,RGS7,RCAN2" Coexpression M1951 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.76E-12 9.89E-08 3.09E-09 3.03E-08 54 490 "RIMKLA,ACHE,MBP,RCSD1,RTN1,SLC44A5,SNX32,GOLGA7B,ANK1,CNIH2,SLC1A6,SLC8A3,GPR153,DLL3,SNCB,NRG3,ATP1A3,GAD2,NKX6-2,LHFPL4,TTC9B,STARD10,CPLX2,POPDC3,FAM69C,TMEM151B,SYT6,BRSK2,GRIK2,GRIK4,SHISA7,USP2,MFSD2A,TLL2,NEURL1,LRTM2,CHRNB2,NECAB2,PACSIN1,MFSD4A,KIAA1755,PLPPR5,SYNC,DNAJC6,PTHLH,PTPRE,PLPPR4,KCNJ10,CCDC3,KCNK2,DPP6,RAP1GAP,RAVER2,RCAN2" Coexpression M2105 Genes whose expression was significantly and positively correlated with the number of perineuronal oligodendrocytes in the layer III of BA9 brain region. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.03E-11 3.08E-07 9.32E-09 9.13E-08 70 756 "RBM10,ECSIT,ADAR,RTN1,TUBB4A,CHST15,ACTL6B,FOXG1,MOG,C1orf61,APBA2,DGKZ,CLSTN1,ZNF365,MADD,ARFGAP2,NSG2,B3GAT1,SNCB,GABBR1,KIF21B,NMNAT2,ADGRB2,RAP1GAP2,CLASP2,GPR162,GFAP,NCDN,NELL1,GLS,OS9,GNAS,DDHD2,NRDC,NRGN,CAMK2G,TMEM151B,NUCB1,OMG,INA,CD81,PADI2,DCLK1,PDE2A,ACOT7,HPCA,FADS2,FTO,SULT4A1,CABP1,NECAB2,CRMP1,PTPA,FEZ1,MICAL2,ATRNL1,NCAN,KLK6,KIAA0513,RIMS3,ELMO1,COPS7A,SV2A,ARNT2,KCNK1,WIPF2,CAMK1G,RGS7,LINC00599,RCAN2" Coexpression M1551 Genes whose splicing in neocortex was most affected by knock out of NOVA2 [GeneID=4858]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.08E-11 4.14E-07 1.22E-08 1.19E-07 15 43 "ANK3,NTNG1,TACC2,CLSTN1,NCDN,CAMK2G,GRIK2,GRIN1,TPM3,CADM1,KCNMA1,KCNQ2,RAP1GAP,EPB41,EPB41L2" Coexpression 15665281-Table2 Human Brain_Wong05_96genes GeneSigDB 6.65E-11 6.74E-07 1.93E-08 1.89E-07 18 67 "SH3GL2,GAS7,ASCL1,TAGLN3,NEUROD1,CACNA1A,GRM3,CELF3,PAX6,DCLK1,SCRG1,NCAN,PTPRE,KCNC1,PTPRZ1,KCNK1,KCNQ2,L1CAM" Coexpression 14997935-Table1 Human Brain_Mukasa04_29genes GeneSigDB 7.50E-11 7.61E-07 2.11E-08 2.07E-07 12 26 "CDHR1,TUBB4A,ANK3,SNCB,MYT1L,MYH7,ABCC8,INA,PSD,KCNQ2,L1CAM,RGS7" Coexpression 19377508-SuppTable1 Human Lymphoma_Chin09_1201genes GeneSigDB 1.04E-10 1.06E-06 2.86E-08 2.80E-07 65 695 "EPS8,MAP6,LGR4,DUSP27,KCNIP2,RTN1,GPR158,SCN3A,LRRTM4,BCAR3,SELL,NTNG1,MAGI3,BCAN,NLGN1,BCAS1,MSR1,YPEL4,SHANK2,SLN,SORCS3,ARPP21,NPAS3,GFRA1,MLC1,ABCC8,SYT4,POPDC3,TCF7L2,GPR19,GRID1,RFFL,GRIK2,TF,OLR1,OMG,CRB1,P2RX7,GUCY1A1,PCDH9,ADGRG1,LRTM2,CHI3L2,JAM2,GDAP1L1,SERPINE2,NMT2,ATCAY,FEZ1,ARHGEF4,CTNND1,CTNND2,MAPK10,PROX1,SIRPA,TMCC2,KCNMA1,NAV2,KCNQ2,DLG2,SSPN,RAVER2,TMEM100,EPB41L1,UEVLD" Coexpression 17880687-TableS2 Human Embryo_Heim07_2325genes GeneSigDB 1.11E-10 1.12E-06 2.95E-08 2.90E-07 114 1565 "ACER3,TMEM74,RTN3,LDLRAD3,CSMD2,RTKN,MDM4,NDRG2,CLIP1,ADCYAP1R1,FABP7,AMER2,NLGN4X,SCN4B,SEMA6A,PDZD4,ASRGL1,CDC42BPA,RASA3,PKP4,TACC2,SORBS1,SLC1A6,URGCP,CCDC88A,SHANK2,CADPS,CSPG5,TAGLN3,DDX25,B3GAT1,PALLD,GABBR1,KIF21B,CADM3,AHCYL1,LHFPL4,NEK6,CPLX2,FXYD6,NASP,NCAM1,LMO3,RND1,NFIA,GLS,CASTOR3,ZNF638,KAZN,GNAS,GNG3,NODAL,CNTN2,KLHL4,PRUNE2,WSCD1,GPM6B,DDR1,PTBP2,NUDT21,EML4,PSD3,ADAMTS8,CCKBR,LEFTY2,INA,TLL2,CDC42,TPM4,PDE4B,FNDC5,PLEKHB1,JAM2,SEMA5B,TJP2,CCDC136,FAT3,SF1,CRLS1,SNCAIP,TENM4,KCNT2,FEZ1,RBPJ,PRKAB2,PLPP4,FGFR1OP2,TOX,SYTL2,GON4L,SYNC,PMEPA1,CNIH3,SHD,MAGI2,SMG7,PTPRZ1,KCNJ4,RABGAP1L,NAV2,DPP6,DTNA,RTN4,L1CAM,RET,ST8SIA3,JMJD1C,ATL1,SSPN,RPRD1A,EPB41,EPB41L1,EPB41L2,BAALC" Coexpression 15720813-TableS2b Human Brain_Hoelzinger05_117genes GeneSigDB 2.55E-10 2.59E-06 6.63E-08 6.50E-07 19 81 "MOBP,GPAM,MADD,SHANK2,TAGLN3,DKK3,BCL2L2,GFAP,ARHGEF7,GPR19,GRIA1,OPCML,INA,PDE1A,CNTN1,KLK6,KCNK1,RGS7,RCAN2" Coexpression M2013 Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.94E-10 2.98E-06 7.46E-08 7.31E-07 48 445 "EXTL1,SLITRK1,ADD3,TOMM40L,TRIM46,ANK2,LRRC4C,YPEL4,MT3,B3GALT2,SOX5,TTLL9,BCL2L2,RCOR2,ADHFE1,ACSBG1,GPM6A,DDR2,GRM3,P2RX7,PCDH9,CDH10,PDE1A,PDE1C,PDE4B,ZMYND8,SCRG1,NRXN1,CPT1C,DNAJC12,C11orf49,PPP2R5C,NCAN,CTNND1,MAPK10,KIAA0408,WBP1L,LRRTM3,MED24,KCNA4,SRGAP3,C12orf4,SUSD4,DTNA,RFX5,SSPN,LPAR6,TMEM100" Coexpression M11581 Genes up-regulated in pilocytic astrocytoma compared to glioblastoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.32E-10 3.36E-06 8.20E-08 8.04E-07 13 35 "SERPINA3,RTN3,GALNT13,ATP1A2,DKK3,SOX10,DNER,GFAP,TF,SCRG1,PLEKHB1,SERPINE2,OLIG2" Coexpression M9331 "Genes down-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.43E-10 3.48E-06 8.28E-08 8.11E-07 35 264 "ACTN2,EYA1,SOX6,ITSN1,RUFY2,ASCL1,SLN,ADGRA1,MYBPC1,ARPP21,NPAS3,NFIA,PSRC1,WWC1,PRUNE2,CECR2,SYT6,GRIA1,DAAM2,TNR,PCDH9,SCRG1,HEPACAM,SLC25A27,NXPH1,NCAN,NRSN1,FAM131B,PTAFR,CADM2,KCNC1,KCNK1,NAV2,PYGM,SLC25A41" Coexpression M1714 Genes enriched in oligodendrocytes in the adult mouse brain identified through correlation-based searches seeded with the oligodendrocyte cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.98E-10 4.03E-06 9.38E-08 9.20E-07 18 74 "MAG,MBP,ERMN,MOBP,MOG,SOX10,GJB1,MYRF,CNTN2,WSCD1,OMG,DAAM2,CD81,PLEKHB1,ANLN,OPALIN,OLIG1,OLIG2" Coexpression 18277965-Table4b Human Liver_Skawran08_272genes GeneSigDB 4.21E-10 4.27E-06 9.70E-08 9.50E-07 33 240 "MRVI1,SOX6,FOXM1,ASRGL1,APBB1,YPEL4,DKK3,NELL1,ABCC8,VAMP1,GPR19,OLR1,CCKBR,HPS5,ZNF384,PDE3B,CHRM1,TUB,MS4A7,SLC22A6,FADS2,CTNND1,PSMD13,KCNA1,KCNC1,NAV2,PEX5,RAB3IL1,RAD52,USH1C,LMO1,ROM1,BSCL2" Coexpression M2882 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.55E-10 4.61E-06 1.02E-07 1.00E-06 36 280 "CEND1,RTN1,ADCYAP1R1,TMEM156,ASIC4,MOBP,FOXG1,ANK3,SCG3,SLIT1,TAGLN3,ASTN1,SNAP25,ATP1A2,NMNAT2,IDI2-AS1,NAP1L2,LMO3,GFAP,ZEB1,GPR19,KCNK10,PCDH8,PCDH9,PDE2A,CHGA,KIAA1549L,CTNND2,MAPK10,PLPPR1,KCNC1,NTM,SLC6A15,USH1C,EN2,RCAN2" Coexpression M15472 Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.90E-10 5.98E-06 1.30E-07 1.27E-06 42 366 "ABAT,FHL1,SOX6,SH3GL2,AQP4,SLC1A2,ATP1A2,DNER,NAP1L2,SPART,NCAM1,ERBIN,SYT4,SEMA4A,UNC5D,ADGRL3,GPM6B,VSTM2A,INA,PCDH9,PTGDR2,CHGA,TMEFF2,JAM2,CNTN1,SLC36A4,MFSD4A,ETNPPL,PRKACB,RIMS3,ZNF385B,DNAJC6,MAGI2,PTPRZ1,PID1,SUSD4,BEND5,DTNA,TTLL7,SIDT2,TMEM100,RCAN2" Coexpression M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.80E-10 7.91E-06 1.68E-07 1.65E-06 46 428 "PRR5L,RIMKLA,IL17D,SLITRK1,AMPH,PKP4,NTNG1,CCDC80,CACHD1,SLC1A6,SLC14A1,DACH2,ADGRA1,PALLD,GAD2,ADGRB2,LMO3,RHBDL3,C1QC,KAZN,ADGRL3,GPM6B,DDR2,GRIA1,ADAMTS8,GUCY1A1,CDH10,PDE1A,MS4A7,CAMKV,SEMA5B,NEGR1,FAM181B,CNTN1,PRRX1,RBPJ,PROX1,GON4L,PMEPA1,PTHLH,KCNA4,CALN1,RALGDS,DBX2,ABCC9,ABI2" Coexpression M2506 "Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.85E-09 2.89E-05 6.02E-07 5.90E-06 24 146 "SCN3A,SORBS1,SCG3,SLIT1,TAGLN3,SLN,SNAP25,ATP1A2,ZCCHC24,SOX10,EMC1,NFASC,NHLH1,INA,CELF3,PCDH8,SCRG1,CHGA,NRXN1,STMN4,SLC17A6,L1CAM,EEF1A2,LPAR6" Coexpression M10952 "Genes up-regulated in the atria of healthy hearts, compared to venticles." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.25E-09 4.31E-05 8.80E-07 8.62E-06 32 249 "EPS8,ADORA1,ITSN1,DGKZ,ZNF365,CADPS,PDE8B,SLN,ATM,MYBPC1,NMNAT2,ABCC8,OS9,KAZN,PRUNE2,DDR1,NPPA,DDR2,NUCB1,NUMA1,TGFBR3,CD81,LILRA4,PDE2A,PDE4B,FEZ1,MICAL2,VCAN,RABGAP1L,KCNK1,RTN4,EPB41L1" Coexpression M2010 Genes with high-CpG-density promoters (HCP) bearing the bivalent histone H3 trimethylation mark at K4 and K27 (H3K4me3 and H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.34E-09 4.40E-05 8.80E-07 8.63E-06 29 210 "CDHR1,ADORA1,DISP3,SLC30A10,NTNG1,STK32C,SOX1,NMNAT2,CDK5R2,ADAMTS8,GPR88,PTPN5,INA,PCDH8,PCSK2,PRMT8,TUB,KIAA1549L,MFSD4A,TENM4,RGS6,KCNA1,AK5,KCNJ4,KCNK1,KCNMA1,RASGRF1,SLC6A15,RET" Coexpression M1963 Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.14E-08 1.16E-04 2.25E-06 2.20E-05 28 206 "KCNIP2,SLITRK1,RYR1,FGR,SYBU,NSG2,PDE8B,C11orf87,ANO4,GRM3,ZDHHC22,KCNK10,PDE1C,PDYN,CA14,GDAP1L1,PIK3CD,ATCAY,NCAN,KIAA0408,BRINP3,PHYHIP,ELMO1,KCNJ9,KCNN3,DLG2,SLC25A41,LRRC23" Coexpression 17880687-TableS1 Human Embryo_Heim07_1650genes GeneSigDB 1.15E-08 1.17E-04 2.25E-06 2.20E-05 84 1122 "RTN3,CSMD2,RTKN,NDRG2,CLIP1,ADCYAP1R1,FABP7,AMER2,NLGN4X,FHL1,PDZD4,ASRGL1,GAS7,TACC2,SORBS1,SLC1A6,URGCP,CCDC88A,SHANK2,TAGLN3,DDX25,EIF4G3,PALLD,GABBR1,CADM3,AHCYL1,LHFPL4,FXYD6,NASP,NCAM1,LMO3,RND1,SEPT3,NFIA,ARHGEF7,GLS,CASTOR3,ZNF638,KAZN,GNAS,GNG4,KLHL4,PRUNE2,WSCD1,GPM6B,PTBP2,EML4,CCKBR,LEFTY2,INA,CDC42,DCLK1,SEZ6L,TPD52,TPM4,FNDC5,PLEKHB1,SF1,CRLS1,TENM4,KCNT2,FEZ1,RBPJ,PLPP4,TOX,SYTL2,SHD,MAGI2,SMG7,PTPRZ1,KCNJ4,RABGAP1L,NAV2,PEX5,DPP6,RTN4,RET,JMJD1C,RPRD1A,OLIG2,EPB41,EPB41L2,LRRC23,BAALC" Coexpression M2012 Genes up-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.26E-08 1.28E-04 2.42E-06 2.37E-05 37 331 "ABAT,CLIP1,NLGN4X,ASRGL1,ANK2,PKP4,TAGLN3,B3GAT1,KIF1B,RAP1GAP2,CLASP2,NELL1,NHLH1,ASTN2,POPDC3,WSCD1,DDR1,PTBP2,ACOT7,FTO,MICAL1,CRMP1,RBPJ,DZIP3,ARHGEF4,PLPPR1,JAKMIP2,ELMO1,MAGI2,PTPRD,KCND3,KCNN3,NKAIN1,GNE,ZNF248,SH3GLB1,OLIG2" Coexpression 15720813-Table2 Human Brain_Hoelzinger05_59genes GeneSigDB 1.46E-08 1.48E-04 2.74E-06 2.68E-05 14 54 "TAGLN3,DKK3,BCL2L2,ARHGEF7,GPR19,NUCB1,OPCML,INA,PDE1A,KLK6,KIAA0513,KCNK1,RGS7,RCAN2" Coexpression M2107 Genes whose expression significantly and positively correlated with oligodendrocyte density in layer VI of BA9 brain region in patients with bipolar disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.25E-08 3.30E-04 6.00E-06 5.88E-05 58 681 "MAPT,ADAR,RTN1,FABP7,TUBB4A,CHST15,FHL1,FOXG1,C1orf61,CLSTN1,ARFGAP2,NSG2,SLIT1,B3GAT1,ATP1A3,GABBR1,NMNAT2,ADGRB2,LMO3,BCL2L2,NDUFA5,GPR162,NCDN,NELL1,OS9,GNAS,DDHD2,CAMSAP2,CACNA1A,PRUNE2,NRDC,CAMK2G,NUCB1,OMG,INA,CD81,PDE2A,HNRNPK,HPCA,SERPINE2,FTO,SULT4A1,NECAB2,CRMP1,FEZ1,ATRNL1,KIAA0513,RIMS3,ELMO1,COPS7A,SV2A,ARNT2,WIPF2,SLC6A15,CAMK1G,RGS7,LINC00599,RCAN2" Coexpression M9112 Age down-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.46E-08 3.51E-04 6.27E-06 6.14E-05 23 153 "MAPT,FOXG1,SFPQ,ANK2,PPM1E,TAGLN3,ATP2B2,KIF1B,VAMP1,CACNB2,NUDT21,CAMK2A,GRIA1,CCKBR,NRXN1,CNTN1,PRKCG,PRKCZ,PTPRO,KCNJ9,PLEKHB2,RASGRF1,ABI2" Coexpression M2018 Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.93E-08 3.99E-04 7.00E-06 6.86E-05 14 58 "DUSP27,FABP7,AGT,FGF1,CAB39,MLC1,DDR1,AKNA,BTBD17,CP,MASP1,SLC25A18,CAMK1G,VWA5A" Coexpression 19658189-TableS3 Human EmbryonicStemCell_Xu09_1311genes GeneSigDB 8.64E-08 8.76E-04 1.51E-05 1.48E-04 73 969 "ABAT,RCSD1,PAQR6,EXTL1,ACTN2,IL17D,NDRG2,RXRG,SORCS1,ADORA1,GPR158,AGT,SGIP1,ANK2,ANXA7,TACC2,SORBS1,USP16,MSRA,SLC6A9,SLC8A3,CADPS,SCMH1,ASPH,SORCS3,PALLD,DKK3,TNIK,MYH7,ADGRB2,NCAM1,LMO3,NDUFA5,NFIA,POPDC3,DCLK2,KLHL4,NPPA,CACNB2,CAMK2A,PSD3,TMEM25,USP2,GUCY1A2,TLL2,CDH10,MAGI1,DUSP26,NRXN1,NSD2,ETNPPL,PNKD,RNF14,MICAL2,PHACTR3,PROX1,MASP1,BRINP3,ITGAV,SHD,PTPRE,KCNJ11,CAB39L,TMEM255A,DTNA,ABCC9,EEF1A2,SEC61A2,SSPN,SH3GLB1,PLEKHO1,RPE65,LRRC23" Coexpression 18855877-TableS2 Human Sarcoma_Filion09_404genes GeneSigDB 1.32E-07 1.34E-03 2.26E-05 2.22E-04 33 302 "NDRG2,ADARB2,FGF14,FHL1,SYBU,SLC1A2,ZNF365,SLC14A1,USP33,B3GALT2,SOX5,GAD2,COLGALT2,GFAP,LEFTY2,CDH8,CDH10,PDE3B,SCRG1,HPSE2,PHKG1,FADS2,VCAN,PRKACB,IGSF1,CTNND2,BRINP3,KCNMA1,PID1,DTNA,RTN4,RET,RCAN2" Coexpression M1949 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.53E-07 1.55E-03 2.59E-05 2.54E-04 36 349 "FAM43B,DSCAML1,GALNT13,SCN4B,ACTL6B,SLC30A10,FOXG1,CADPS,SORCS3,TMEM151A,ATP2B2,CADM3,RAP1GAP2,GNAS,GNG4,CDK5R2,UNC5D,CNTN2,GRIK3,IGSF21,CDH8,HRH3,PRMT8,TLX1,SULT4A1,RGS6,PLD5,KCNA1,KCNH1,KCNK1,KCNQ2,DSCAM,RASGRF1,CRTAC1,RET,ELAVL3" Coexpression 18565887-TableA8 Human StemCell_Murat08_25genes GeneSigDB 1.73E-07 1.75E-03 2.87E-05 2.81E-04 8 18 "F3,BBOX1,AQP4,MLC1,PAX6,HEPACAM,SLC25A18,DTNA" Coexpression M17173 "Genes up-regulated in the nucleus accumbens (a major reward center in brain) 8 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.89E-07 1.92E-03 3.09E-05 3.03E-04 12 47 "ADAR,ADCYAP1R1,GAD2,KIF1B,CAMK2A,SYT6,GRIA2,GRIN1,USP2,CHRM1,KCNH1,ARNT2" Coexpression 16778177-Table3 Human Brain_Wang06_79genes GeneSigDB 2.43E-07 2.47E-03 3.91E-05 3.84E-04 12 48 "SCNN1D,CLSTN1,EIF4G3,ADGRB2,CAMTA1,TNFRSF1B,CDC42,PIK3CD,CHD5,SDC3,PUM1,PRDM2" Coexpression M11011 Genes down-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.04E-07 3.08E-03 4.82E-05 4.72E-04 22 159 "MAG,MAPT,MOBP,MOG,FOLH1,ATM,SOX10,KIF1B,NFASC,NKX2-2,MYRF,CNTN2,TF,P2RX7,LILRA4,PCSK2,SF1,MAPK8,KLK6,LRP8,RASGRF1,OLIG2" Coexpression M6338 Genes down-regulated in Vd2 gamma delta T cells: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.27E-07 3.31E-03 5.09E-05 4.99E-04 21 147 "EPS8,DUSP27,EXTL1,WLS,ANK3,ITSN1,STARD10,FXYD6,SMOC1,CDH10,CHRM4,ATCAY,OSBPL3,ATRNL1,RIMS3,NAV2,KLRC2,SLC17A6,PLEKHB2,DPP6,L1CAM" Coexpression M8426 Genes up-regulated in pre-B cells: STAT5 knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.54E-07 3.59E-03 5.44E-05 5.33E-04 25 200 "ADGRV1,GRAMD1B,C1orf61,ASCL1,DNAH17,ATP2B2,MYBPC1,B4GALNT1,CAMK2G,GRM3,P2RX7,PADI2,PCSK2,CHGA,HPCA,POU3F4,IGSF1,CTNND1,RIMS3,PTPRZ1,KCNN3,L1CAM,CAMK1G,USH1C,ZNF248" Coexpression M16407 Genes in the expression cluster 'LT-HSC Shared': up-regulated in long term hematopoietic stem cells (LT-HSC) from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.79E-07 3.85E-03 5.74E-05 5.63E-04 32 301 "MAG,MAPT,PAQR6,SGIP1,AQP4,URGCP,LGI3,STARD10,DNER,DCAF5,FAM168A,GLS,EML4,TIE1,TNS1,PCDH9,JAM2,CNTN1,PRRX1,SF1,FMN2,EDRF1,PROX1,ANKS1B,HP1BP3,PTPRZ1,SRGAP3,BEND5,SLC6A15,TTLL7,ELAVL4,EPB41L2" Coexpression 19192944-TableS4 Human Ovarian_Crijns09_2394Genes_17PathwayPredictor GeneSigDB 5.71E-07 5.79E-03 8.51E-05 8.34E-04 102 1584 "MAG,MAPT,APC2,ACTN2,ECSIT,ADCY2,RYR1,CDC7,FGF1,FGF14,SEMA6A,SELL,SEMA6C,APC,NTNG1,MAGI3,SORBS1,NLGN1,LRRC4C,ARHGAP5,SLC8A2,SLC8A3,PDE8B,FYN,ATP2B2,GART,NCAM1,NDUFA5,FGF17,GJB1,ARHGEF7,SEMA4A,GNAS,ROBO3,UNC5D,BTRC,CNTN2,CACNA1A,CACNA1E,CACNB2,TCF7L2,CAMK2A,CAMK2G,GRIN1,CCKBR,PTPN5,INA,GUCY1A2,P2RX7,GUCY1A1,TJP1,DAAM2,TNFRSF1B,CDC42,TNR,MAGI1,PDE1A,PDE1C,PDE2A,PDE3B,CHRM1,CHRM4,JAM2,PHKG1,NRXN2,SEMA5B,NEGR1,PIK3CD,TJP2,VAV2,PLXNB3,CNTN1,PTPA,PPP3CB,CSF3R,PRKAB2,PRKACB,SDC3,PRKCG,PRKCZ,ARHGEF4,MAPK8,MAPK10,DPYSL5,ITGAV,MAGI2,PARD6A,SRGAP3,AK5,PYGM,KLRC3,RASGRF1,PAK5,L1CAM,VANGL2,CACNG7,EFNA3,ABI2,EPB41,EPB41L1,EPB41L2,RASGRP2" Coexpression 19185848-TableS4 Mouse StemCell_Read09_300genes GeneSigDB 6.83E-07 6.92E-03 1.00E-04 9.83E-04 26 221 "MAPT,APC2,RTN1,PPM1E,APC,MADD,GABBR1,TNIK,DNER,NFASC,GPR162,ARHGEF7,FADS2,PACSIN1,RNF14,PPP3CB,MAPK10,DNAJC6,STMN4,SV2A,SRGAP3,KCNK2,KCNQ2,DLG2,PAK5,L1CAM" Coexpression M1935 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation marks at k4 (H3K4me3) and K27 ((H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.80E-07 7.91E-03 1.12E-04 1.10E-03 20 142 "ADORA1,DISP3,ELMOD1,NTNG1,STK32C,MEGF11,SOX1,NMNAT2,ADAMTS8,GPR88,PTPN5,INA,PCDH8,TUB,KIAA1549L,TENM4,AK5,KCNJ4,KCNMA1,EPB41L1" Coexpression 16288009-SuppTable2 Human StemCell_Moreno05_297genes GeneSigDB 7.87E-07 7.98E-03 1.12E-04 1.10E-03 29 266 "EPS8,MEG3,F3,BBOX1,SELL,NLGN1,SLC8A2,ASCL1,CSPG5,SNCB,CADM3,ADGRB2,NFASC,COLGALT2,NCDN,NEUROD1,AJAP1,ASTN2,ADGRL3,DCLK1,SEZ6L,FADS2,CABP1,VCAN,IGSF1,BRINP3,PAK5,BSCL2,RCAN2" Coexpression M10332 Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.46E-07 8.58E-03 1.19E-04 1.17E-03 13 63 "SH3GL2,APBB1,DGKZ,ATP1A2,SOX10,NRGN,GRIA1,GRIA2,NTSR2,KCNMA1,PYGM,RASGRF1,EEF1A2" Coexpression M2875 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 8.74E-07 8.86E-03 1.21E-04 1.19E-03 20 143 "RTN1,ASIC4,ANK3,SCG3,ASTN1,SNAP25,ATP1A2,NAP1L2,LMO3,GPR19,KCNK10,PCDH8,PDE2A,CHGA,KIAA1549L,MAPK10,NTM,SLC6A15,USH1C,RCAN2" Coexpression 20145155-TableS2 Human StemCell_Lottaz10_24genes GeneSigDB 1.10E-06 1.11E-02 1.50E-04 1.47E-03 8 22 "BCAN,ASCL1,CSPG5,DLL3,GRIA2,SEZ6L,KCNQ2,ELAVL4" Coexpression 16849537-SuppTable2 Human StemCell_Davicioni06_534genes GeneSigDB 1.54E-06 1.56E-02 2.08E-04 2.04E-03 43 500 "ABAT,WLS,CLIP1,NLGN4X,ASRGL1,ANK2,PKP4,TAGLN3,B3GAT1,KIF1B,RAP1GAP2,CLASP2,NELL1,RGL1,NHLH1,ASTN2,POPDC3,KAZN,WSCD1,DDR1,PTBP2,PSD3,ACOT7,NRXN2,FTO,MICAL1,CRMP1,SNCAIP,RBPJ,DZIP3,ARHGEF4,JAKMIP2,ELMO1,MAGI2,PTPRD,KCND3,KCNN3,NKAIN1,GNE,RGS10,ZNF248,SH3GLB1,OLIG2" Coexpression 12037678-Table2 Human Brain_Mukasa02_24genes GeneSigDB 1.62E-06 1.64E-02 2.15E-04 2.11E-03 8 23 "SLC1A2,RPH3A,SNAP25,SNCB,MYT1L,INA,MICAL2,RGS7" Coexpression M14791 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.66E-06 1.68E-02 2.15E-04 2.11E-03 30 291 "RTN1,ADCY2,SORCS1,NLGN4X,ANK2,DOCK10,ATP1A2,SOX10,NAP1L2,MIR100HG,NEUROD1,WSCD1,GPM6B,VSTM2A,USP2,TNS1,PCDH9,ANO5,CHGA,JAM2,NRXN1,MFSD4A,CP,FMN2,BRINP3,TMEM255A,FAM13C,BEND5,L1CAM,TMEM100" Coexpression M2242 Category A genes: p53-dependent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.66E-06 1.68E-02 2.15E-04 2.11E-03 65 896 "MAG,EMID1,MEG3,SLITRK1,RYR1,TUBB4A,ACTL6B,BCAR3,MOBP,ANK3,APBA2,ASCL1,DDX25,DKK3,MYT1L,CADM3,ILDR2,ARPP21,SALL3,LHFPL4,TTC9B,ADAM15,NPAS3,KIRREL3,SLCO1C1,GNG3,DDR1,NRGN,CECR2,VXN,BRSK2,ADAMTS8,PTPN5,MAGI1,FNDC5,CHGA,SEMA5B,CNTN1,C11orf49,NECAB2,POU3F2,MED1,PNKD,TENM4,NCAN,DOCK7,CALY,CMTM5,MAPK10,GON4L,PTCH1,PRDM2,CDH20,PTPRD,NTM,KCNJ11,KLRC2,SLC17A6,DSCAM,BEND5,EEF1A2,RNF220,ELAVL3,RASGRP2,SEZ6" Coexpression M1349 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.78E-06 1.81E-02 2.29E-04 2.24E-03 12 57 "RIMKLA,AMPH,RASA3,NSG2,TAGLN3,FXYD6,SYT4,PCDH8,PRRX1,CRMP1,ELAVL3,ELAVL4" Coexpression M2737 Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of EZH2 [Gene ID=2146] gene. MSigDB C6: Oncogenic Signatures (v6.0) 2.37E-06 2.41E-02 3.01E-04 2.95E-03 23 193 "CLIP1,SLC14A1,B4GALNT1,FXYD6,POPDC3,GPM6B,PTBP2,PCDH9,ADGRG1,TUB,DNAJC12,KIAA0513,PMEPA1,PTHLH,CNIH3,KCNA1,KCNA2,KCNJ10,L1CAM,SLC6A15,TTLL7,VWA5A,TMEM100" Coexpression M1712 Genes enriched in neurons in the adult mouse brain identified through correlation-based searches seeded with neuron cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.51E-06 2.55E-02 3.14E-04 3.08E-03 13 69 "MEG3,RTN1,SH3GL2,MADD,NSG2,SNAP25,GPR162,CAMK2A,GRIA2,GRIA4,REPS2,PACSIN1,DPP6" Coexpression 15888489-Table1 Mouse Brain_Chung05_134genes GeneSigDB 2.65E-06 2.69E-02 3.28E-04 3.22E-03 16 103 "CDHR1,CEND1,FGF1,SOX6,AQP4,SORCS3,ATP1A2,MYH7,FXYD6,CADM1,PPP2R5C,PTPRZ1,NTM,CALN1,SLC17A6,RASGRF1" Coexpression M7281 "Top 200 genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer), by ChIP-chip assay on an 88K microarray (all promoters)." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.09E-06 3.13E-02 3.78E-04 3.70E-03 23 196 "EYA1,CSMD3,AMER2,ELMOD1,MOBP,AQP4,SLC8A3,SLN,BRINP2,ASTN1,CCDC181,ARPP21,KIRREL3,GPM6B,GPR88,GRM3,TMEM257,ELMO1,CDH20,SLC17A6,ATL1,RNF220,EN2" Coexpression M6316 Genes up-regulated in macrophages: control versus Sendai virus infection. MSigDB C7: Immunologic Signatures (v6.0) 3.64E-06 3.69E-02 4.39E-04 4.30E-03 21 170 "ADD3,SNX30,CHST15,SEMA6A,BBOX1,SELL,USP28,ST8SIA1,TMEM108,SOX1,CLASP2,GNAS,TGFBR3,PACSIN1,TOX,PMEPA1,KCNA2,DPP6,JMJD1C,RGS10,PLEKHO1" Coexpression M4287 Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 2 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 3.68E-06 3.73E-02 4.39E-04 4.30E-03 23 198 "MAPT,ACHE,KCNIP2,LINC01354,CSPG5,SALL3,ANO4,FAM69C,VXN,LEFTY2,MAEL,PAX6,PDE1A,TUB,PLPPR5,RGMA,NTM,CCDC3,NAV2,DNAH9,KLRC3,DSCAM,FGFBP3" Coexpression M9933 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 6h. MSigDB C7: Immunologic Signatures (v6.0) 4.01E-06 4.06E-02 4.72E-04 4.63E-03 23 199 "ACHE,CEND1,FAM43B,DSCAML1,SCN4B,ASIC4,ANK2,CLSTN1,ADGRA1,DKK3,CADM3,ACSL6,GRIK2,GRIK3,TUB,RAB39A,PLPP4,OLFM3,OLIG1,TMEM255A,DBX2,INSYN2,LINC00599" Coexpression M9289 Genes up-regulated in CD11c+ monocytes: control versus HAdv5 infection. MSigDB C7: Immunologic Signatures (v6.0) 4.36E-06 4.42E-02 5.08E-04 4.98E-03 23 200 "SYNDIG1,RYR1,DRAXIN,BCO1,ATP1A3,PALLD,SCN3B,GAD2,ADAM15,FAM168A,DIRAS1,GRIK4,CELF3,CD81,IGSF21,CHRM1,CHRNB2,POU3F2,CALY,SRGAP3,DLG3,OLIG1,PID1" Coexpression 11559565-Table3 Human Brain_Rickman01_53genes GeneSigDB 4.57E-06 4.63E-02 5.26E-04 5.16E-03 11 52 "NCAM1,GPR17,GRIA2,OPCML,PDE4B,SERPINE2,VCAN,PRKACB,ZBTB16,KLRC3,DTNA" Coexpression M2616 Genes transiently induced only by the second pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.75E-06 4.82E-02 5.41E-04 5.31E-03 105 1723 "RIMKLA,MAPT,ACHE,EYA1,IL17D,DSCAML1,TUBB4A,GPR158,ACTL6B,FHL1,UNC79,SLC30A10,FOXG1,PDZD4,SGIP1,ANK1,PI16,DGKZ,SLC1A2,KIAA1614,RPH3A,SLC2A5,MSR1,ASCL1,SLCO1A2,NAXD,CAPRIN2,DDX25,BRINP2,SORCS3,SNAP25,CCDC181,PHYHIPL,SOX5,NMNAT2,JPH4,SALL3,BCL2L2,FGF17,GJB1,RND1,SEPT3,CDK5R2,CNTN2,CACNA1A,WSCD1,NEU4,ZEB1,DIRAS1,GPR26,VSTM2A,GRIA1,GRID1,GRIK2,SHISA7,CCKBR,MFSD2A,FBXL16,TLL2,KCNK10,PAX6,TNFRSF1B,PCDH9,CDH8,PDE3B,HAPLN2,NTSR2,ANO5,MS4A7,HPCA,HEPACAM,NRXN1,NEGR1,OPALIN,PMP2,COL9A2,IFFO1,ATCAY,POU3F4,RGS6,MICAL2,ATRNL1,CMTM5,PROX1,DPYSL5,ANKS1B,PHYHIP,MAGI2,KCNA6,KCNC1,NTM,KCNJ9,KCNJ10,FAM57B,ATG16L1,L1CAM,INSYN2,PHC2,SYT15,SLC39A12,SSPN,EFNA3,GPR61,RCAN2,UEVLD" Coexpression M2773 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of ALK [Gene ID=238] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 4.85E-06 4.92E-02 5.46E-04 5.36E-03 19 146 "NDRG2,ADCY2,RXRG,ADORA3,BCO1,NMNAT2,FXYD6,GPR162,KAZN,CAMK2A,PCDH8,CHRM4,VAV2,KIAA0408,ITIH2,PTPRZ1,KCNJ9,ST8SIA3,LINC00599" Coexpression 19286929-SuppTable2h Mouse Lung_Rangasamy09_98genes GeneSigDB 5.49E-06 5.57E-02 6.12E-04 6.00E-03 14 85 "SCN3A,AQP4,ATP1A2,ATP1A3,SCN3B,CACNB2,GRIA2,GRIA4,GRIK2,SLC25A27,KCNT2,KCND3,SLC6A15,CACNG7" Coexpression 18614019-TableS4b Mouse StemCell_Fazzio08_466genes GeneSigDB 5.61E-06 5.69E-02 6.15E-04 6.03E-03 30 309 "EPS8,MEG3,EYA1,RTKN,MDM4,BCAR3,PDZD4,CNIH2,APC,TACC2,ST8SIA1,SFMBT2,NCAM1,DCLK2,GNAS,PSRC1,WSCD1,B4GALNT4,PTBP2,P2RX7,CDC42,RBFOX2,TPM3,TPM4,MAGI1,CELF5,FEZ1,DNAJC6,DTNA,UEVLD" Coexpression M2009 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.65E-06 5.72E-02 6.15E-04 6.03E-03 32 341 "DSCAML1,RXRG,GALNT13,SCN4B,FGF14,C1QTNF4,HPCAL4,FOXG1,SLC7A14,SORCS3,TMEM151A,ATP2B2,CADM3,RAP1GAP2,NELL1,CNTN2,GRIK3,GRIN1,CCKBR,TNFRSF1B,IGSF21,CDH8,HRH3,TLX1,SULT4A1,PRKCZ,CA10,KCNH1,KCNQ2,SLC17A6,CRTAC1,ST8SIA3" Coexpression M7123 Genes up-regulated in peripheral blood monocytes (PMBC): healthy versus mixed infection sepsis. MSigDB C7: Immunologic Signatures (v6.0) 5.75E-06 5.83E-02 6.20E-04 6.07E-03 22 189 "ADORA1,LRRC4C,ATP2B2,ILDR2,TTC9B,CPLX2,RND1,DCLK2,WWC1,GRIK4,PAX6,PDE1A,HPCA,CABP1,PRRX1,RIMS4,PROX1,PARD6A,CRTAC1,RGS7,EEF1A2,EFNA3" Coexpression 17297478-SuppTable5 Human Intestine_Vecchi07_1024genes GeneSigDB 6.10E-06 6.18E-02 6.51E-04 6.38E-03 57 781 "ABAT,FHL1,SOX6,FOXM1,AMPH,SH3GL2,AQP4,SLC1A2,CSPG5,SMARCE1,ATP1A2,GABBR1,DNER,NAP1L2,NASP,SPART,NCAM1,ERBIN,SYT4,SEMA4A,UNC5D,ADGRL3,GPM6B,EML4,VSTM2A,INA,PCDH9,PTGDR2,HMGB1,CHGA,TMEFF2,JAM2,ANLN,CNTN1,SLC36A4,NSD2,MFSD4A,ETNPPL,PRKACB,PROX1,KLK6,RIMS3,ZNF385B,DNAJC6,PMEPA1,LRP8,MAGI2,PTPRZ1,PID1,ATG16L1,SUSD4,BEND5,DTNA,TTLL7,SIDT2,TMEM100,RCAN2" Coexpression M768 Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.53E-06 6.62E-02 6.89E-04 6.76E-03 15 98 "EYA1,NDRG2,RYR1,SEMA6A,PKP4,SCN3B,ARPP21,NCAM1,NHLH1,POPDC3,GNAS,PTBP2,PDE2A,TUBB2B,KCNN3" Coexpression M1796 The glioblastoma multiforme (GBM) plasticity signature: genes up-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.86E-06 6.95E-02 7.17E-04 7.03E-03 26 250 "MBP,F3,CNIH2,BCAS1,SCG3,TAGLN3,ASPH,CPLX2,NASP,ALDH1L1,SMOC1,NCDN,SYT4,GPM6A,VWC2,VXN,OMG,ACOT7,TMEFF2,ANLN,NXPH1,CP,PSD,CADM2,PTPRD,RLBP1" Coexpression M2577 "Top 50 marker genes for anaplastic oligodendroglioma (AO), a class of high grade glioma." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.76E-06 7.87E-02 8.03E-04 7.87E-03 10 45 "ASIC1,APC2,API5,PDE8B,NCAM1,ABCC8,GRIK2,FLRT1,ELMO1,OLIG2" Coexpression M2817 Genes up-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.53E-06 9.66E-02 9.76E-04 9.56E-03 22 195 "MEG3,LINC00461,DGKD,SLC1A2,B3GAT1,ATP1A3,ILDR2,CPLX2,NCDN,CAMK2A,GRIA1,OPCML,UBTF,PRKAB2,PRKCG,KIAA0513,PLPPR5,ZC3H11A,SMG7,NTM,PYGM,DNM2" Coexpression M1726 Transcripts showing subcellular localization only to proximal dendrites in the adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-05 1.02E-01 1.02E-03 1.00E-02 9 37 "ANK2,RPH3A,NSG2,NRGN,INA,HPCA,SULT4A1,NECAB2,DNAJC6" Coexpression 19286929-SuppTable2a Mouse Lung_Rangasamy09_168genes GeneSigDB 1.06E-05 1.08E-01 1.07E-03 1.05E-02 19 154 "CDC7,SELL,DOCK10,APC,NLGN1,CLASP2,NELL1,SEPT3,OPCML,PCDH9,CDH8,CDH10,ZMYND8,NEGR1,DOCK7,CADM2,PCDH15,SSPN,VWA5A" Coexpression M1962 Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.27E-05 1.29E-01 1.27E-03 1.24E-02 9 38 "EXTL1,SOX6,YPEL4,OPCML,CALY,LRRTM3,KCNA4,PAK5,TMEM100" Coexpression 19523942-Table2 Human Brain_Potter09_64genes GeneSigDB 1.39E-05 1.41E-01 1.37E-03 1.34E-02 11 58 "TTYH1,SERPINA3,FABP7,BBOX1,ASCL1,SNAP25,GFAP,GPM6A,PMP2,CRMP1,PTPRZ1" Coexpression M8082 Genes up-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 1.43E-05 1.45E-01 1.39E-03 1.36E-02 22 200 "SLITRK1,HOGA1,PLA2G6,FGF14,UNC79,NLGN1,SFMBT2,SOX1,ARPP21,C11orf87,GPR162,VWC2,GRIA2,PCDH8,CDH10,FAT3,PRKCG,PLPPR1,NTM,PCDH15,VANGL2,BAALC" Coexpression M2781 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.50E-05 1.52E-01 1.45E-03 1.42E-02 18 144 "NDRG2,RXRG,GAS7,API5,CAB39,NMNAT2,LMO3,GPR162,GPR88,PADI2,PCDH8,PDE4B,DNAJC12,PID1,SLC17A6,EEF1A2,SSPN,ARHGAP12" Coexpression M1914 Genes up-regulated in neural stem cells (NSC) at 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.53E-05 1.55E-01 1.46E-03 1.43E-02 28 293 "ABAT,ZFYVE27,AGT,FGF1,APBA2,SORBS1,PHYHIPL,MLC1,GRIA2,USP2,SEZ6L,PDE1C,PDE2A,TMEFF2,PRRX1,CP,SNCAIP,SIRPA,PTPRE,KCNC1,PTPRO,SRGAP3,PYGM,RALGDS,DTNA,RFX5,VWA5A,SEZ6" Coexpression 20599952-Table1 Human BoneMarrow_Maisel10_105genes GeneSigDB 1.54E-05 1.56E-01 1.46E-03 1.43E-02 15 105 "MAG,ABAT,MBP,TUBB4A,MOBP,MOG,NKX2-2,GPM6B,GPR17,TF,PCDH9,FEZ1,KLK6,PTCH1,BAALC" Coexpression M5547 Age up-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.58E-05 1.60E-01 1.48E-03 1.46E-02 26 262 "EYA1,RYR1,ADD3,AGT,FGF1,BBOX1,PPFIA1,SLC14A1,ASCL1,ALDH4A1,FYN,PALLD,ZCCHC24,AHCYL1,GFAP,ACSBG1,MLC1,NKX2-2,DDR1,VCAN,ITGAV,CEP170,GNE,SSPN,SH3GLB1,OLIG2" Coexpression 19185848-Table1 Mouse StemCell_Read09_41genes GeneSigDB 1.60E-05 1.62E-01 1.49E-03 1.46E-02 9 39 "SEMA6A,ACTL6B,NEUROD1,NHLH1,CNTN2,CELF5,MAPK10,L1CAM,ELAVL4" Coexpression 15750623-Table1 Mouse Brain_Johansson05_60genes GeneSigDB 1.65E-05 1.67E-01 1.52E-03 1.49E-02 11 59 "NDRG2,CLSTN1,NCDN,ACSBG1,GNAS,MMD2,CAMK2G,ACOT7,CALY,TMCC2,PLEKHB2" Coexpression M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.74E-05 1.77E-01 1.59E-03 1.56E-02 39 480 "MEG3,MRVI1,FHL1,ANK2,SORBS1,CACHD1,SLC14A1,ATP1A2,FYN,PALLD,DKK3,SALL3,FXYD6,NCAM1,MIR100HG,SMOC1,GPM6B,DDR2,TGFBR3,MFSD2A,TNS1,PCDH9,SCRG1,TUB,CCDC136,PRRX1,CNRIP1,FEZ1,MASP1,KCNMA1,NAV2,BEND5,DTNA,VANGL2,SSPN,SH3GLB1,RAVER2,TMEM100,RCAN2" Coexpression M2370 "Oligodendrocyte core differentiation genes: up-regulated in Oli-neo cells (oligodendroglial precursor) at 10 h after treatment with PD174265, dexamethasone or isotretinoin [PubChem=4709, 5743, 5282379]." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.99E-05 2.02E-01 1.80E-03 1.77E-02 9 40 "ABAT,MBP,DSCAML1,SORBS1,OPCML,SLC25A27,ELMO1,KCNA1,PAK5" Coexpression 19074870-SuppTable4a Human StemCell_Harris08_490genes GeneSigDB 2.16E-05 2.19E-01 1.93E-03 1.90E-02 34 398 "SERPINA3,ACHE,ACLY,MBP,SYT9,NDRG2,FGF1,FOXM1,SNAP25,SNCB,ATP1A2,FYN,DKK3,SOX10,GJB1,SYT4,NKX2-2,GRIA1,GRIA4,P2RX7,CDC42,TPD52,PCSK2,PLXNB3,CNTN1,MICAL1,COL9A2,PTPA,SYTL2,ANKS1B,KCNK1,NUP214,RET,RLBP1" Coexpression Atlas cerebral cortex cerebral cortex Human Protein Atlas 2.78E-283 1.23E-279 1.23E-279 1.11E-278 416 1431 "DPF1,MAG,TTYH1,ABAT,MAP6,RIMKLA,ASIC1,MAPT,APC2,TMEM74,MBP,SYT9,SYNDIG1,PAQR6,EXTL1,CEND1,IL17D,CSMD2,KCNIP2,CSMD3,ADARB2,KLHL32,RTN1,ADCY2,DSCAML1,SLITRK1,GALNT13,ADCYAP1R1,FABP7,SORCS1,ERMN,ADORA1,TUBB4A,AMER2,NLGN4X,DRAXIN,GPR158,SNX32,AGT,SCN3A,LRRTM4,DISP3,FGF1,LRRC7,FGF14,ACTL6B,C1QTNF4,ASIC4,GOLGA7B,UNC79,ELMOD1,HPCAL4,MOBP,FOXG1,C1orf61,PDZD4,TRIM46,AMPH,ERICH3,SGIP1,ANK2,CNIH2,SH3GL2,PPM1E,APBA2,APC,NTNG1,GAS7,SLITRK3,BCAN,SYBU,NLGN1,JAKMIP3,LRRC4C,BCAS1,SHTN1,AQP4,SLC1A2,ZNF365,SLC7A14,SLC1A6,RPH3A,LRRC55,SLC8A2,YPEL4,SLC8A3,MT3,SHANK2,RTP5,DACH2,CADPS,ASCL1,CGREF1,SCG3,CSPG5,SLCO1A2,SPHKAP,LGI3,SLIT1,TAGLN3,DLL3,DDX25,BRINP2,SORCS3,ASTN1,C10orf105,B3GAT1,TMEM108,ADGRA1,SNAP25,TMEM151A,SNCB,ATP1A2,NRG3,ATP1A3,PHYHIPL,ATP2B2,MEGF11,DKK3,GABBR1,SCN3B,SOX1,MYT1L,B3GALT2,KIF21B,CADM3,SOX10,ILDR2,GAD2,NMNAT2,JPH4,B4GALNT1,NKX6-2,ARPP21,SALL3,LHFPL4,TTC9B,CPLX2,ADGRB2,DNER,NAP1L2,NPAS3,NFASC,NCAM1,LMO3,C11orf87,CLASP2,COLGALT2,SMOC1,GPR162,GFAP,NCDN,RCOR2,HEPN1,NELL1,KIRREL3,NEUROD1,RND1,SEPT3,AJAP1,SLCO1C1,ACSBG1,MLC1,ABCC8,RHBDL3,PCDH11X,SYT4,POPDC3,LUZP2,DCLK2,NKX2-2,GNG3,GNG4,MYRF,CDK5R2,UNC5D,MMD2,PSRC1,CNTN2,ADGRL3,CNDP1,ANO4,CACNA1A,WSCD1,GPM6A,GPM6B,FAM69C,ACSL6,CACNA1E,LRIT2,NEU4,PRLHR,B4GALNT4,GPR19,DIRAS1,GPR26,NRGN,HAP1,CAMK2A,PCDHGA3,CECR2,TMEM151B,SYT6,VSTM2A,BRSK2,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GPR88,GRM3,OLR1,OMG,SHISA7,OPCML,CCKBR,CRB1,PTPN5,FBXL16,INA,TLL2,CELF3,TMEM257,ZDHHC22,KCNK10,PAX6,IGSF21,TNR,PADI2,PCDH8,PCDH9,CDH8,CDH10,DCLK1,HRH3,SEZ6L,LGI1,PCSK2,PDE2A,PRMT8,PIRT,PDYN,GPR37L1,HAPLN2,NTSR2,ACOT7,BEST3,SCRG1,TMPRSS5,CA14,LRTM2,CHRM1,PLEKHB1,CHRM4,CHRNB2,TMEFF2,HPCA,HEPACAM,DUSP26,NLGN3,DLGAP3,GDAP1L1,KIAA1549L,NRXN1,NRXN2,CAMKV,SEMA5B,NEGR1,ANLN,CPT1C,OPALIN,ST8SIA5,FLRT1,FAM181B,SULT4A1,PLXNB3,CNTN1,PMP2,CABP1,CELF5,NECAB2,P2RY12,PACSIN1,FAT3,ATCAY,NXPH1,BTBD17,CNRIP1,POU3F2,POU3F4,ETNPPL,CRMP1,RGS6,NKAIN4,FEZ1,ATRNL1,CHD5,NCAN,RIMS4,PHACTR3,PRKACB,FMN2,CALY,CMTM5,RAB39A,PRKCG,PLPP4,PRKCZ,ARHGEF4,SLC45A1,CTNND2,NRSN1,MAPK10,HES5,FAM131B,NOS1AP,KIAA0408,BRINP3,KLK6,PSD,KIAA0513,RIMS3,DPYSL5,ANKS1B,PHYHIP,PLPPR5,TUBB2B,LRRTM3,DNAJC6,CA10,PLPPR1,JAKMIP2,CADM2,CNIH3,LRP8,SHD,RGMA,MAGI2,STMN4,KCNA1,KCNA2,OLFM3,KCNA4,CDH20,PTPRD,PLPPR4,KCNC1,PTPRZ1,KCNH1,SV2A,SRGAP3,NTM,AK5,KCNJ4,KCNJ9,KCNJ10,TMCC2,ARNT2,PCDH15,KCNN3,KCNQ2,DLG2,NKAIN1,HS3ST4,OLIG1,KLRC2,KLRC3,SLC25A48,CALN1,SLC17A6,FAM57B,DPP6,SLC25A41,SLC25A18,RAP1GAP,DSCAM,RASGRF1,DBX2,DTNA,PAK5,L1CAM,SLC6A15,CRTAC1,CAMK1G,ST8SIA3,RFX4,RGR,RGS7,FAM135B,INSYN2,ATL1,TTLL7,EEF1A2,RLBP1,SEC61A2,SFXN5,SLC39A12,CACNG7,PIANP,GPR61,FGFBP3,CBLN2,SLC4A10,ELAVL3,ELAVL4,ROM1,C2orf80,OLIG2,RPE65,SEZ6,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.85E-64 8.21E-61 2.74E-61 2.46E-60 81 194 "TTYH1,MEG3,NDRG2,SLITRK1,ADCYAP1R1,FABP7,SCN3A,LINC00461,C1orf61,SOX6,DOCK10,BCAN,LRRC4C,ST8SIA1,SLC1A2,MT3,NSG2,ASCL1,SCG3,CSPG5,ASTN1,FYN,PHYHIPL,ZCCHC24,SOX10,SALL3,MIR4697HG,DNER,FXYD6,NPAS3,NCAM1,SMOC1,HEPN1,FAM168A,NFIA,LUZP2,DCLK2,NKX2-2,GNG4,ADGRL3,GPM6A,GPM6B,ZEB1,GPR17,VXN,GRIA2,GRIA4,OMG,SEZ6L,ADGRG1,SCRG1,NLGN3,SERPINE2,NRXN1,CNTN1,PMP2,SPATA6,ATCAY,NXPH1,NKAIN4,NCAN,SDC3,CTNND2,HES5,MASP1,BRINP3,ANKS1B,LRRTM3,PTCH1,PLPPR1,PTPRD,PTPRZ1,NTM,PCDH15,PANTR1,OLIG1,KLRC2,PID1,DPP6,FGFBP3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.85E-64 8.21E-61 2.74E-61 2.46E-60 81 194 "TTYH1,MEG3,NDRG2,SLITRK1,ADCYAP1R1,FABP7,SCN3A,LINC00461,C1orf61,SOX6,DOCK10,BCAN,LRRC4C,ST8SIA1,SLC1A2,MT3,NSG2,ASCL1,SCG3,CSPG5,ASTN1,FYN,PHYHIPL,ZCCHC24,SOX10,SALL3,MIR4697HG,DNER,FXYD6,NPAS3,NCAM1,SMOC1,HEPN1,FAM168A,NFIA,LUZP2,DCLK2,NKX2-2,GNG4,ADGRL3,GPM6A,GPM6B,ZEB1,GPR17,VXN,GRIA2,GRIA4,OMG,SEZ6L,ADGRG1,SCRG1,NLGN3,SERPINE2,NRXN1,CNTN1,PMP2,SPATA6,ATCAY,NXPH1,NKAIN4,NCAN,SDC3,CTNND2,HES5,MASP1,BRINP3,ANKS1B,LRRTM3,PTCH1,PLPPR1,PTPRD,PTPRZ1,NTM,PCDH15,PANTR1,OLIG1,KLRC2,PID1,DPP6,FGFBP3,OLIG2" Coexpression Atlas PCBC_EB_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_1000 PCBC 3.30E-59 1.46E-55 3.66E-56 3.29E-55 160 997 "C1orf194,MAP6,MAPT,APC2,ADGRV1,RTN1,SLITRK1,RXRG,GALNT13,FABP7,AMER2,AGT,LINC00461,DISP3,ACTL6B,HPCAL4,C1orf61,PDZD4,PPM1E,LRRC4C,ST8SIA1,SLC1A6,LRRC55,PKNOX2,SLC8A2,SLC8A3,NSG2,DACH2,ASCL1,SCG3,CSPG5,SLIT1,TAGLN3,DLL3,SLN,SORCS3,B3GAT1,SNAP25,TMEM151A,PHYHIPL,MYBPC1,SOX1,MYT1L,SOX5,KIF21B,SOX10,ILDR2,NMNAT2,ENKUR,NKX6-2,ARPP21,SALL3,TTC9B,CPLX2,DNER,NCAM1,LMO3,SMOC1,GFRA1,NELL1,NEUROD1,SEPT3,ABCC8,RHBDL3,NHLH1,SYT4,GNG3,MYRF,CDK5R2,CNTN2,ADGRL3,GPM6A,GPM6B,NPPA,CAMK2A,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,GRIK3,TF,OLR1,OMG,CRB1,GUCY1A1,CELF3,KCNK10,DAAM2,PAX6,PCDH8,CDH8,CDH10,SEZ6L,LGI1,PDE1A,FNDC5,SCRG1,HPSE2,CHGA,DUSP26,GDAP1L1,CAMKV,SEMA5B,FLRT1,FAM181B,SULT4A1,CELF5,PRRX1,NECAB2,FAT3,ATCAY,BTBD17,POU3F2,POU3F4,SNCAIP,TENM4,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,PHACTR3,FMN2,KIAA1755,RAB39A,PLD5,HES5,KLK6,PSD,RIMS3,DPYSL5,ITIH2,SHD,STMN4,KCNA2,CDH20,PTPRD,KCNA6,KCNC1,PTPRO,KCND3,KCNJ4,KCNK2,KCNMA1,KCNQ2,NKAIN1,HS3ST4,TMEM255A,SLC17A6,FAM57B,USH1C,RFX4,SLC39A12,CBLN2,LINC00599,ELAVL3,ELAVL4,RPE65,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.29E-53 4.13E-49 8.26E-50 7.41E-49 91 340 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,GRAMD1B,AMER2,SCN3A,LINC00461,ASIC4,GOLGA7B,UNC79,C1orf61,SOX6,SGIP1,ANK3,BCAN,LRRC4C,CCDC88A,NSG2,ASCL1,CSPG5,DLL3,SNAP25,ATP1A3,MYT1L,SOX10,JPH4,ARPP21,TTC9B,DNER,NPAS3,NCAM1,SMOC1,NELL1,NFIA,NKX2-2,GNG3,CACNA1A,GPM6A,GPM6B,CACNA1E,CAMK2G,VSTM2A,GRIA1,GRIA2,GRIA4,GRIK3,OPCML,PTPN5,INA,PCDH9,CDH8,ADGRG1,SCRG1,TMEFF2,SERPINE2,KIAA1549L,NRXN1,NRXN2,NEGR1,CNTN1,PMP2,NXPH1,CRMP1,NCAN,PHACTR3,PLPP4,CTNND2,BRINP3,ANKS1B,PTCH1,CA10,PLPPR1,STMN4,PTPRZ1,NTM,PCDH15,OLIG1,KLRC2,DPP6,PAK5,CRTAC1,FGFBP3,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.54E-49 6.86E-46 1.14E-46 1.03E-45 162 1198 "DPF1,ASIC1,SYNDIG1,MEG3,CSMD2,CSMD3,RTN1,SLITRK1,FABP7,GRAMD1B,AMER2,GPR158,SCN3A,LINC00461,KIAA1109,ASIC4,GOLGA7B,UNC79,MOBP,C1orf61,SOX6,TRIM46,SGIP1,ANK1,ANK3,PI16,SLITRK3,BCAN,SYBU,LRRC4C,SLC8A3,MT3,CCDC88A,SHANK2,NSG2,ASCL1,SCG3,CSPG5,DNAH17,DLL3,SNAP25,ATP1A3,FYN,SCN3B,USP33,MYT1L,KIF21B,SOX10,JPH4,ARPP21,TTC9B,GART,DNER,NAP1L2,NPAS3,NCAM1,C11orf87,CLASP2,SMOC1,FGF17,NELL1,SEPT3,NFIA,ABCC8,CASTOR3,NKX2-2,GNG3,CAMSAP2,CACNA1A,GPM6A,GPM6B,CACNA1E,B4GALNT4,GPR17,TCF12,CAMK2G,VSTM2A,GRIA1,GRIA2,GRIA4,GRIK3,OPCML,SPX,PTPN5,INA,CELF3,REPS2,TNS1,PCDH9,CDH8,PCSK2,ACOT7,ADGRG1,SCRG1,CHGA,TMEFF2,GDAP1L1,SERPINE2,KIAA1549L,NRXN1,NRXN2,NEGR1,UBTF,CCDC136,CNTN1,PMP2,CELF5,ATCAY,NXPH1,CRMP1,NKAIN4,NCAN,PHACTR3,PRKACB,PLPP4,PRKCZ,CTNND2,HES5,KIAA0408,MASP1,BRINP3,ANKS1B,PLPPR5,PTCH1,CA10,PLPPR1,PMEPA1,CADM2,COPS7A,CEP170,STMN4,PTPRZ1,NTM,KCNK2,PCDH15,KCNMA1,OLIG1,KLRC2,DPP6,RALGDS,RAP1GAP,ATN1,RASGRF1,RTN4,PAK5,L1CAM,BSDC1,CRTAC1,ZYG11B,JMJD1C,FAM135B,EEF1A2,CACNG7,VWA5A,FGFBP3,SLC4A10,ELAVL3,ELAVL4,C2orf80,EN2,OLIG2,SEZ6" Coexpression Atlas PCBC_EB_fibroblast_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 9.17E-45 4.07E-41 5.82E-42 5.22E-41 140 992 "C1orf194,MAP6,MAPT,APC2,ADGRV1,RTN1,RXRG,FABP7,AGT,LINC00461,ACTL6B,HPCAL4,C1orf61,PPM1E,GAS7,ST8SIA1,SLC1A6,LRRC55,SLC8A2,SLC8A3,NSG2,DACH2,ASCL1,SCG3,CSPG5,SLIT1,TAGLN3,DLL3,SLN,SORCS3,B3GAT1,IGSF9B,SNAP25,TMEM151A,PHYHIPL,MYBPC1,MYT1L,KIF21B,SOX10,ILDR2,NMNAT2,ENKUR,ARPP21,CPLX2,DNER,NCAM1,GFRA1,NELL1,GJB1,MLC1,NHLH1,SYT4,GNG3,MYRF,CDK5R2,CNTN2,ADGRL3,GPM6A,NPPA,CAMK2A,CECR2,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIN1,TF,OLR1,CRB1,INA,GUCY1A1,CELF3,PAH,KCNK10,PAX6,PCDH8,CDH8,CDH10,SEZ6L,LGI1,PDE1A,FNDC5,SCRG1,CHGA,GDAP1L1,NRXN1,NRXN2,SEMA5B,FLRT1,FAM181B,SULT4A1,CELF5,PRRX1,BTBD17,POU3F2,SNCAIP,TENM4,NKAIN4,KCNT2,CSF3R,ATRNL1,PLCH2,NCAN,RIMS4,PHACTR3,CALY,CTNND2,HES5,PSD,RIMS3,DPYSL5,ITIH2,SHD,STMN4,KCNA2,CDH20,PTPRD,KCNA6,PLPPR4,KCNC1,PTPRO,KCND3,SRGAP3,KCNJ4,KCNK2,KCNMA1,KCNQ2,HS3ST4,TMEM255A,SLC17A6,USH1C,RFX4,LINC00599,ELAVL3,ELAVL4,RPE65,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 3.76E-44 1.67E-40 2.09E-41 1.87E-40 113 662 "MAP6,ASIC1,MEG3,RTN1,DSCAML1,AMER2,SCN3A,LINC00461,FGF14,ASIC4,SOX6,CDC42BPA,ANK2,ANK3,APBA2,APC,SYBU,SHANK2,NSG2,DACH2,CADPS,ASCL1,SCG3,TAGLN3,DLL3,SMARCE1,B3GAT1,PHYHIPL,MYT1L,KIF21B,GAD2,NKX6-2,TTC9B,DNER,NCAM1,MIR100HG,CLASP2,GFRA1,NELL1,NEUROD1,SEPT3,ARHGEF7,PCDH11X,NHLH1,SYT4,DCLK2,NKX2-2,GNAS,ROBO3,GNG3,CNTN2,GPM6A,ZEB1,TCF12,PSD3,GRIA2,GRIA4,CRB1,TMEM25,INA,GUCY1A2,CELF3,PCDH9,DCLK1,RBFOX2,SEZ6L,FNDC5,ADGRG1,GDAP1L1,NRXN1,NRXN2,NEGR1,FTO,CELF5,ATCAY,POU3F2,CRMP1,PPP3CB,NCAN,PRKACB,FMN2,NRSN1,MAPK8,KIAA0408,ANKS1B,TUBB2B,DNAJC6,PLPPR1,JAKMIP2,ELMO1,PRDM2,SHD,CEP170,STMN4,PTPRD,SV2A,NTM,KCNMA1,PANTR1,PID1,SLC17A6,RALGDS,DSCAM,PAK5,L1CAM,LMO1,CBLN2,LINC00599,ELAVL3,ELAVL4,EN2,EPB41,SEZ6" Coexpression Atlas PCBC_ratio_EB amniotic fluid MSC_vs_EB blastocyst_cfr-2X-p05 EB amniotic fluid MSC_vs_EB blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.88E-44 3.06E-40 3.40E-41 3.05E-40 119 738 "DPF1,TTYH1,MAPT,APC2,CNTNAP3,SLC25A25,PLEKHG5,RTN1,ADCYAP1R1,TUBB4A,SLC44A5,CHST15,DRAXIN,LINC00461,DISP3,ACTL6B,TRIM46,SEMA6C,CNIH2,CACHD1,ST8SIA1,LRRC55,NSG2,DACH2,CADPS,GPR153,SCG3,CSPG5,SLIT1,ASTN1,B3GAT1,SNAP25,ATP1A2,ATP1A3,PHYHIPL,KIF21B,CADM3,NMNAT2,JPH4,CPLX2,ADGRB2,DNER,NFASC,NCAM1,COLGALT2,RCOR2,SEPT3,NFIA,RHBDL3,NHLH1,ROBO3,GNG4,CNTN2,WWC1,WSCD1,GPM6A,GPM6B,DDR1,DIRAS1,TMEM151B,BRSK2,CROCCP2,LEFTY2,INA,CELF3,ZDHHC22,PAX6,DCLK1,ARHGAP19,FNDC5,ADGRG1,TMEFF2,JAM2,DUSP26,GDAP1L1,NRXN2,SEMA5B,CPT1C,MICAL1,COL9A2,FAT3,ATCAY,POU3F2,CRMP1,NKAIN4,FEZ1,RIMS4,CTNND2,HES5,FAM131B,KIAA0408,MASP1,TOX,RIMS3,DPYSL5,TUBB2B,JAKMIP2,SHD,STMN4,CDH20,SRGAP3,TMCC2,KCNQ2,NKAIN1,SLC17A6,FAM57B,L1CAM,SLC6A15,RFX4,ATL1,EEF1A2,VANGL2,CACNG7,EFNA3,LINC00599,ELAVL3,ELAVL4,RCAN2,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.35E-43 2.38E-39 2.38E-40 2.13E-39 83 357 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,BCAN,LRRC4C,MT3,NSG2,ASCL1,SCG3,CSPG5,SNAP25,MYT1L,SOX10,JPH4,TTC9B,DNER,NCAM1,FGF17,NELL1,GNG3,CAMSAP2,CACNA1A,GPM6A,CACNA1E,GPR17,VSTM2A,GRIA1,GRIA2,GRIA4,OPCML,PTPN5,INA,REPS2,CDH8,PCSK2,ACOT7,SCRG1,TMEFF2,GDAP1L1,KIAA1549L,NRXN1,NRXN2,NEGR1,CNTN1,PMP2,NXPH1,CRMP1,NKAIN4,NCAN,PHACTR3,CTNND2,BRINP3,ANKS1B,PLPPR5,CA10,PLPPR1,COPS7A,STMN4,PTPRZ1,NTM,KCNK2,KCNMA1,OLIG1,DPP6,RAP1GAP,PAK5,BSDC1,JMJD1C,CACNG7,SLC4A10,ELAVL3,ELAVL4,C2orf80,EN2,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.55E-41 1.13E-37 1.03E-38 9.23E-38 81 355 "MAP6,ASIC1,MEG3,RTN1,AMER2,SCN3A,FGF14,ASIC4,CDC42BPA,ANK2,ANK3,APBA2,APC,SHANK2,NSG2,CADPS,ASCL1,SCG3,TAGLN3,PHYHIPL,MYT1L,KIF21B,GAD2,DNER,NCAM1,MIR100HG,CLASP2,NELL1,NEUROD1,SEPT3,ARHGEF7,NHLH1,DCLK2,NKX2-2,GNG3,CNTN2,GPM6A,GRIA2,GRIA4,INA,CELF3,PCDH9,DCLK1,RBFOX2,FNDC5,ADGRG1,NRXN1,NRXN2,FTO,CELF5,ATCAY,POU3F2,CRMP1,NCAN,PRKACB,FMN2,MAPK8,KIAA0408,ANKS1B,TUBB2B,DNAJC6,PLPPR1,JAKMIP2,PRDM2,CEP170,STMN4,PTPRD,SV2A,NTM,KCNMA1,PANTR1,RALGDS,DSCAM,PAK5,L1CAM,LMO1,LINC00599,ELAVL3,ELAVL4,EN2,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.07E-39 4.73E-36 3.94E-37 3.54E-36 78 343 "MAP6,MEG3,ADARB2,KLHL32,RTN1,FABP7,AMER2,SCN3A,ASRGL1,CDC42BPA,ANK2,ANK3,APC,SHTN1,RUFY2,CCDC88A,SHANK2,NSG2,CADPS,PHYHIPL,DKK3,SCN3B,MYT1L,B3GALT2,KIF21B,NMNAT2,JPH4,DNER,NAP1L2,NCAM1,LMO3,CLASP2,GFRA1,SEPT3,SYT4,GNG3,GPM6A,CACNA1E,PSD3,GRIA2,INA,CELF3,DCLK1,RBFOX2,SEZ6L,PCSK2,CHGA,TMEFF2,CADM1,NRXN1,NRXN2,NEGR1,CNTN1,FAT3,POU3F2,CRMP1,NCAN,PRKACB,SDC3,MAPK8,KIAA0408,RIMS3,DPYSL5,ANKS1B,DNAJC6,LRP8,CEP170,STMN4,PTPRD,NTM,ARNT2,DPP6,RALGDS,PAK5,L1CAM,ELAVL3,ELAVL4,EN2" Coexpression Atlas PCBC_EB_blastocyst_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 3.55E-39 1.58E-35 1.21E-36 1.09E-35 132 995 "SERPINA3,C1orf194,MAP6,MAPT,ADGRV1,RTN1,RXRG,FABP7,AMER2,AGT,LINC00461,ACTL6B,HPCAL4,C1orf61,PDZD4,SOX6,LRRC4C,ST8SIA1,SLC1A6,SLC2A5,LRRC55,PKNOX2,SLC8A3,NSG2,DACH2,ASCL1,SCG3,CSPG5,SLIT1,TAGLN3,SLN,SORCS3,B3GAT1,SNAP25,TMEM151A,PHYHIPL,SOX1,SOX5,SOX10,ILDR2,ENKUR,NKX6-2,SALL3,CPLX2,DNER,NCAM1,LMO3,GFRA1,NELL1,GJB1,SEPT3,NHLH1,SYT4,GNG3,MYRF,CNTN2,GPM6A,NPPA,CAMK2A,TMEM151B,BRSK2,GRIA1,GRIA2,GRIA4,TF,OLR1,GUCY1A1,CELF3,PAH,KCNK10,PAX6,PCDH8,CDH8,CDH10,LGI1,FNDC5,SCRG1,HPSE2,CHGA,GDAP1L1,SEMA5B,FLRT1,FAM181B,CELF5,COL9A2,PRRX1,NECAB2,BTBD17,POU3F2,POU3F4,SNCAIP,TENM4,NKAIN4,KCNT2,CSF3R,ATRNL1,NCAN,RIMS4,PHACTR3,KIAA1755,CTNND2,HES5,BRINP3,PSD,RIMS3,DPYSL5,ITIH2,SHD,STMN4,CDH20,PTPRD,PLPPR4,PTPRO,KCNQ2,NKAIN1,OLIG1,DNAH9,TMEM255A,SLC17A6,FAM57B,DPP6,CRTAC1,USH1C,RFX4,SYT15,SLC39A12,CBLN2,LINC00599,ELAVL3,ELAVL4,EN2,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.28E-38 5.68E-35 4.06E-36 3.64E-35 119 830 "TTYH1,EPS8,ABAT,MAP6,MEG3,ADGRV1,LDLRAD3,CSMD2,WLS,NDRG2,CLIP1,ADCY2,ADCYAP1R1,FABP7,SORCS1,ERMN,AGT,SCN3A,LINC00461,SEMA6A,C1orf61,ASRGL1,APC,BCAN,LRRC4C,CLSTN1,SLC1A2,ARHGAP5,MT3,ASCL1,PDE8B,SCG3,CSPG5,CCDC181,ATP1A2,PHYHIPL,DKK3,TNIK,SOX5,CADM3,ILDR2,ENKUR,MIR4697HG,DNER,FXYD6,NPAS3,NCAM1,SMOC1,GFAP,INKA2,HEPN1,NELL1,SEPT3,NFIA,MLC1,LUZP2,DCLK2,PSRC1,WWC1,WSCD1,GPM6A,GPM6B,CACNB2,ZEB1,TCF12,VXN,PSD3,GRID1,GRM3,OMG,OPCML,CD81,SEZ6L,LGI1,ADGRG1,SCRG1,JAM2,SERPINE2,CADM1,KIAA1549L,NRXN1,SEMA5B,TJP2,FAM181B,PMP2,FAT3,NXPH1,SNCAIP,TENM4,NKAIN4,NCAN,SDC3,IGSF1,CTNND2,HES5,MASP1,TOX,LRRTM3,PTCH1,ITGAV,PLPPR1,PRDM2,LRP8,RGMA,STMN4,PTPRZ1,SV2A,NTM,PCDH15,KCNN3,PANTR1,OLIG1,DPP6,DTNA,RTN4,RFX4,FGFBP3,C2orf80,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.97E-38 1.32E-34 8.79E-36 7.89E-35 69 274 "ASIC1,MEG3,CSMD2,CSMD3,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,LRRC4C,NSG2,ASCL1,SNAP25,SCN3B,MYT1L,JPH4,TTC9B,DNER,NCAM1,C11orf87,CLASP2,NELL1,SEPT3,GNG3,GPM6A,CACNA1E,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,CELF3,CDH8,CHGA,TMEFF2,GDAP1L1,KIAA1549L,NRXN1,NRXN2,NEGR1,CCDC136,CNTN1,CELF5,ATCAY,NXPH1,CRMP1,NCAN,PHACTR3,PRKACB,PRKCZ,KIAA0408,BRINP3,ANKS1B,CA10,PLPPR1,STMN4,OLIG1,DPP6,PAK5,EEF1A2,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 5.00E-38 2.22E-34 1.39E-35 1.25E-34 123 895 "DPF1,TTYH1,APC2,MEG3,ADGRV1,RTKN,CLIP1,KLHL32,RTN1,SLITRK1,ADCYAP1R1,FABP7,CHST15,LRRTM4,LINC00461,FOXG1,SOX6,ASRGL1,ANK2,PPM1E,NLGN1,LRRC4C,SHTN1,MADD,ASCL1,SCG3,TAGLN3,SORCS3,ASTN1,B3GAT1,SNAP25,NRG3,PHYHIPL,ATP2B2,SOX5,CADM3,ILDR2,LHFPL4,KIF1B,NPAS3,NASP,NCAM1,LMO3,GFRA1,FGF17,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,DCLK2,SEMA4A,GNG3,CACNA1A,GPM6A,GPM6B,FAM69C,ACSL6,TCF7L2,DIRAS1,HAP1,AZIN2,PTBP2,TMEM151B,VSTM2A,PSD3,GRIK2,MFSD2A,TJP1,CELF3,CDK11B,PCDH9,CDH8,MAGI1,PRMT8,ADGRG1,TUB,JAM2,HPCA,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SPATA6,SLC36A4,FAT3,ATCAY,ACBD5,CRMP1,FEZ1,NCAN,FMN2,IGSF1,CTNND2,MAPK10,HES5,PROX1,BRINP3,TOX,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,L1CAM,RFX4,RFX5,CACNG7,ELAVL3,ELAVL4,BSCL2,OLIG2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.29E-36 5.72E-33 3.37E-34 3.02E-33 100 624 "MAP6,MEG3,WLS,ADARB2,KLHL32,RTN1,FABP7,AMER2,GPR158,SCN3A,LINC00461,SOX6,ASRGL1,CDC42BPA,ANK2,ANK3,APC,SHTN1,CLSTN1,RUFY2,CCDC88A,SHANK2,NSG2,CADPS,TAGLN3,PHYHIPL,DKK3,SCN3B,MYT1L,B3GALT2,KIF21B,NMNAT2,JPH4,DNER,NAP1L2,NCAM1,LMO3,CLASP2,GFRA1,SEPT3,OS9,SYT4,GNG3,GPM6A,CACNA1E,PSD3,AKNA,GRIA2,INA,CELF3,ZDHHC22,DCLK1,RBFOX2,SEZ6L,PCSK2,ADGRG1,SCRG1,CHGA,TUB,TMEFF2,CADM1,NRXN1,NRXN2,NEGR1,CNTN1,CELF5,BTF3L4,IFFO1,FAT3,POU3F2,SF1,CRMP1,RGS6,NCAN,PRKACB,SDC3,MAPK8,KIAA0408,RIMS3,DPYSL5,ANKS1B,DNAJC6,LRP8,CEP170,STMN4,PTPRD,PTPRZ1,NTM,ARNT2,DPP6,RALGDS,PAK5,L1CAM,FAM135B,PIANP,LINC00599,ELAVL3,ELAVL4,EN2,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.43E-36 1.08E-32 6.00E-34 5.39E-33 73 330 "MAP6,MEG3,WLS,RTN1,FABP7,AMER2,GPR158,SCN3A,LINC00461,ANK2,ANK3,APC,NSG2,CADPS,TAGLN3,PHYHIPL,DKK3,SCN3B,MYT1L,B3GALT2,KIF21B,NMNAT2,JPH4,DNER,NCAM1,LMO3,CLASP2,GFRA1,SEPT3,OS9,SYT4,GNG3,GPM6A,CACNA1E,AKNA,GRIA2,INA,CELF3,ZDHHC22,DCLK1,RBFOX2,SEZ6L,PCSK2,ADGRG1,SCRG1,TUB,TMEFF2,NRXN1,NRXN2,NEGR1,CNTN1,CELF5,FAT3,POU3F2,SF1,CRMP1,NCAN,PRKACB,KIAA0408,DPYSL5,DNAJC6,CEP170,STMN4,NTM,DPP6,RALGDS,PAK5,L1CAM,LINC00599,ELAVL3,ELAVL4,EN2,RCAN2" Coexpression Atlas PCBC_ratio_EB_from-plasmid_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-method_plasmid_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.96E-36 2.65E-32 1.39E-33 1.25E-32 46 115 "DPF1,MAPT,APC2,RTN1,ADCYAP1R1,LINC00461,DISP3,ANK2,CNIH2,LRRC55,NSG2,GPR153,SCG3,SLIT1,SNAP25,ATP1A3,PHYHIPL,KIF21B,CADM3,NMNAT2,CPLX2,DNER,NFASC,NCAM1,SEPT3,NHLH1,ROBO3,CNTN2,GPM6B,BRSK2,INA,CELF3,DCLK1,ARHGAP19,FNDC5,ADGRG1,GDAP1L1,ATCAY,CTNND2,KIAA0408,STMN4,SLC17A6,FAM57B,LINC00599,ELAVL3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.33E-35 5.90E-32 2.95E-33 2.65E-32 73 338 "MAP6,ASIC1,MEG3,RTN1,DSCAML1,AMER2,SCN3A,LINC00461,SOX6,ANK2,ANK3,APC,NSG2,DACH2,CADPS,ASCL1,SCG3,TAGLN3,DLL3,B3GAT1,PHYHIPL,MYT1L,KIF21B,DNER,NCAM1,MIR100HG,CLASP2,GFRA1,NEUROD1,SEPT3,ARHGEF7,NHLH1,ROBO3,GNG3,CNTN2,GPM6A,ZEB1,TCF12,PSD3,GRIA2,CRB1,TMEM25,INA,CELF3,PCDH9,DCLK1,RBFOX2,FNDC5,ADGRG1,ATCAY,POU3F2,CRMP1,NCAN,PRKACB,FMN2,NRSN1,MAPK8,KIAA0408,TUBB2B,PLPPR1,JAKMIP2,CEP170,STMN4,PANTR1,PID1,RALGDS,PAK5,LINC00599,ELAVL3,ELAVL4,EN2,EPB41,SEZ6" Coexpression Atlas PCBC_EB_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500 PCBC 1.57E-35 6.99E-32 3.33E-33 2.99E-32 88 499 "C1orf194,MAP6,MAPT,ADGRV1,RTN1,RXRG,FABP7,AGT,LINC00461,ACTL6B,C1orf61,LRRC55,NSG2,DACH2,ASCL1,SCG3,CSPG5,SLIT1,TAGLN3,SLN,B3GAT1,SNAP25,TMEM151A,PHYHIPL,MYBPC1,SOX1,SOX10,ILDR2,ENKUR,CPLX2,DNER,NCAM1,GFRA1,NELL1,NHLH1,SYT4,GNG3,MYRF,CNTN2,GPM6A,CAMK2A,BRSK2,GRIA1,GRIA2,GRIA4,TF,OLR1,GUCY1A1,CELF3,KCNK10,PCDH8,SEZ6L,LGI1,FNDC5,SCRG1,CHGA,GDAP1L1,FAM181B,CELF5,PRRX1,NECAB2,BTBD17,POU3F2,POU3F4,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,PHACTR3,HES5,RIMS3,DPYSL5,ITIH2,SHD,STMN4,CDH20,PTPRD,PTPRO,KCNQ2,TMEM255A,SLC17A6,USH1C,RFX4,LINC00599,ELAVL3,ELAVL4,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.86E-35 8.26E-32 3.75E-33 3.37E-32 57 196 "MAP6,ASIC1,MEG3,RTN1,AMER2,SCN3A,ANK2,ANK3,APC,NSG2,CADPS,ASCL1,SCG3,TAGLN3,PHYHIPL,MYT1L,KIF21B,DNER,NCAM1,MIR100HG,CLASP2,NEUROD1,SEPT3,ARHGEF7,NHLH1,GNG3,CNTN2,GPM6A,GRIA2,INA,CELF3,PCDH9,DCLK1,RBFOX2,FNDC5,ADGRG1,ATCAY,POU3F2,CRMP1,NCAN,PRKACB,FMN2,MAPK8,KIAA0408,TUBB2B,PLPPR1,JAKMIP2,CEP170,STMN4,PANTR1,RALGDS,PAK5,LINC00599,ELAVL3,ELAVL4,EN2,EPB41" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.71E-34 2.09E-30 9.10E-32 8.17E-31 81 441 "MAP6,ACHE,CEND1,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,SORCS1,TUBB4A,SCN3A,UNC79,SGIP1,ANK2,APBA2,APBB1,SLC7A14,NSG2,CADPS,ASCL1,SCG3,TAGLN3,DDX25,SNAP25,ATP1A3,PHYHIPL,SCN3B,SOX10,TTC9B,NAP1L2,NFASC,NCAM1,GFRA1,SEPT3,ASTN2,DCLK2,GNG3,B4GALNT4,GPR17,GRIA2,GRIA4,GRIK2,INA,CELF3,TNR,PCDH9,DCLK1,LGI1,ACOT7,SCRG1,CHGA,TMEFF2,NLGN3,GDAP1L1,SERPINE2,CADM1,NRXN1,CNRIP1,CRMP1,KCNT2,FEZ1,NRSN1,MAPK10,PROX1,KIAA0408,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRZ1,DLG2,L1CAM,CRTAC1,RET,ST8SIA3,RGS7,ATL1,CACNG7,LMO1,ELAVL4,BSCL2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.38E-34 2.84E-30 1.18E-31 1.06E-30 72 347 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,AMER2,SCN3A,LINC00461,KIAA1109,ASIC4,MOBP,C1orf61,ANK1,ANK3,LRRC4C,SLC8A3,SHANK2,NSG2,ASCL1,DNAH17,SNAP25,USP33,MYT1L,KIF21B,JPH4,TTC9B,DNER,NAP1L2,NCAM1,NELL1,ABCC8,GNG3,GPM6A,CACNA1E,B4GALNT4,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,NXPH1,CRMP1,NCAN,PHACTR3,PRKACB,BRINP3,ANKS1B,CA10,PLPPR1,CADM2,CEP170,STMN4,OLIG1,DPP6,RASGRF1,RTN4,PAK5,L1CAM,ZYG11B,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_1000 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000 PCBC 6.84E-34 3.04E-30 1.22E-31 1.09E-30 124 998 "TTYH1,RIMKLA,MAPT,CDHR1,CEND1,FAM43B,CSMD2,ADCYAP1R1,RYR1,FABP7,TUBB4A,DRAXIN,SCN4B,ACTL6B,HPCAL4,ANK1,CNIH2,PPM1E,SESN3,BCAN,SORBS1,NLGN1,STK32C,LRRC55,CGREF1,GPR153,SCG3,CSPG5,ALDH4A1,IGSF9B,TMEM151A,SNCB,ATP1A2,ATP1A3,SOX1,CADM3,NMNAT2,JPH4,LHFPL4,CPLX2,DNER,NAP1L2,LMO3,ALDH1L1,SMOC1,INKA2,ACSBG1,ABCC8,RHBDL3,SYT4,GNG3,GNG4,CNTN2,CACNA1A,ACSL6,DIRAS1,TMEM151B,SYT6,VSTM2A,GRIA4,GRM3,SPX,FBXL16,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,DCLK1,HRH3,CHGA,CHRNB2,TMEFF2,GDAP1L1,NRXN1,NRXN2,CAMKV,NEGR1,TJP2,DNAJC12,ST8SIA5,CABP1,ATCAY,BTBD17,CP,POU3F4,CRMP1,SNCAIP,NKAIN4,RIMS4,SLC45A1,IGSF1,FAM131B,ECE2,KLK6,TOX,DPYSL5,PHYHIP,LRRTM3,JAKMIP2,OLFM3,PLPPR4,PARD6A,PTPRO,PTPRZ1,NTM,AK5,RABGAP1L,KCNMA1,KCNN3,KCNQ2,PYGM,FAM57B,SLC6A15,ST8SIA3,RGS7,ATL1,CACNG7,FGFBP3,LINC00599,C2orf80,RASGRP2,SEZ6,BAALC" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.32E-33 5.85E-30 2.25E-31 2.02E-30 113 849 "MAP6,MAPT,ACHE,APC2,CEND1,EYA1,CSMD3,NDRG2,RTN1,ADCYAP1R1,FABP7,PNMA8B,SORCS1,TUBB4A,SCN3A,DISP3,ACTL6B,UNC79,SGIP1,ANK2,CNIH2,APBA2,APBB1,SLC7A14,NSG2,CADPS,ASCL1,SCG3,TAGLN3,DDX25,ASTN1,SNAP25,ATP1A3,PHYHIPL,SCN3B,TNIK,CADM3,SOX10,TTC9B,NAP1L2,NFASC,NCAM1,GFRA1,SEPT3,SYT4,ASTN2,DCLK2,GNG3,CACNA1E,B4GALNT4,GPR17,HAP1,GRIA2,GRIA4,GRIK2,GRIK3,FBXL16,INA,CELF3,TNR,PCDH9,CDH10,DCLK1,LGI1,ACOT7,SCRG1,CHGA,CHRNB2,TMEFF2,NLGN3,GDAP1L1,SERPINE2,CADM1,NRXN1,SULT4A1,CNTN1,ATCAY,CNRIP1,CRMP1,KCNT2,FEZ1,PHACTR3,SDC3,CMTM5,NRSN1,MAPK10,PROX1,KIAA0408,DPYSL5,TUBB2B,DNAJC6,JAKMIP2,STMN4,KCNA4,PTPRZ1,SV2A,SRGAP3,KCNN3,DLG2,RALGDS,L1CAM,SLC6A15,CRTAC1,RET,ST8SIA3,RGS7,ATL1,CACNG7,LMO1,ELAVL3,ELAVL4,BSCL2,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.94E-33 8.61E-30 3.19E-31 2.86E-30 73 363 "MAP6,ASIC1,MEG3,RTN1,AMER2,SCN3A,ANK2,ANK3,APC,SYBU,NSG2,CADPS,ASCL1,SCG3,TAGLN3,SMARCE1,PHYHIPL,MYT1L,KIF21B,NKX6-2,TTC9B,DNER,NCAM1,MIR100HG,CLASP2,NEUROD1,SEPT3,ARHGEF7,PCDH11X,NHLH1,SYT4,GNAS,GNG3,CNTN2,GPM6A,GRIA2,INA,GUCY1A2,CELF3,PCDH9,DCLK1,RBFOX2,SEZ6L,FNDC5,ADGRG1,GDAP1L1,NEGR1,ATCAY,POU3F2,CRMP1,PPP3CB,NCAN,PRKACB,FMN2,MAPK8,KIAA0408,TUBB2B,PLPPR1,JAKMIP2,ELMO1,SHD,CEP170,STMN4,PANTR1,SLC17A6,RALGDS,PAK5,CBLN2,LINC00599,ELAVL3,ELAVL4,EN2,EPB41" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.46E-33 1.09E-29 3.90E-31 3.50E-30 104 733 "DPF1,TTYH1,ABAT,APC2,MEG3,ADGRV1,RTN1,SLITRK1,ADCYAP1R1,FABP7,CHST15,LRRTM4,SEMA6A,FHL1,FOXG1,ANK2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,PHYHIPL,CADM3,ILDR2,LHFPL4,NPAS3,NASP,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,RHBDL3,ASTN2,SEMA4A,GNG3,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,TCF7L2,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,GRIK2,MFSD2A,CELF3,PAX6,PCDH9,CDH8,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,CRMP1,FEZ1,NCAN,FMN2,IGSF1,MAPK10,HES5,BRINP3,TOX,DPYSL5,TUBB2B,JAKMIP2,LRP8,SHD,STMN4,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,ELAVL3,BSCL2,LRRC23" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.03E-33 1.34E-29 4.63E-31 4.16E-30 105 748 "DPF1,TTYH1,ABAT,APC2,CEND1,MEG3,RTN1,ADCYAP1R1,FABP7,ERMN,CHST15,LRRTM4,LINC00461,FOXG1,SEMA6C,ANK2,CNIH2,NTNG1,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,SNAP25,NRG3,SOX5,CADM3,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,CACNB2,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,GRIK2,MFSD2A,PAX6,PCDH9,CDH8,PRMT8,TUB,JAM2,HPCA,NLGN3,GDAP1L1,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,NKAIN4,FEZ1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,CA10,SHD,STMN4,CDH20,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,L1CAM,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.14E-33 2.73E-29 9.09E-31 8.16E-30 78 423 "MAP6,CEND1,EYA1,CSMD3,NDRG2,RTN1,ADCYAP1R1,FABP7,TUBB4A,SCN3A,UNC79,SGIP1,ANK2,APBA2,APBB1,SLC7A14,NSG2,CADPS,ASCL1,SCG3,TAGLN3,SNAP25,ATP1A3,PHYHIPL,SCN3B,CADM3,TTC9B,NAP1L2,NFASC,NCAM1,GFRA1,SEPT3,SYT4,ASTN2,GNG3,B4GALNT4,GPR19,HAP1,VSTM2A,GRIA2,GRIA4,INA,CELF3,TNR,PCDH9,DCLK1,ACOT7,CHGA,TMEFF2,GDAP1L1,SERPINE2,CADM1,NRXN1,SULT4A1,CRMP1,FEZ1,NRSN1,MAPK10,PROX1,KIAA0408,DPYSL5,TUBB2B,DNAJC6,JAKMIP2,STMN4,KCNA4,PTPRZ1,SV2A,SRGAP3,DLG2,RALGDS,L1CAM,RET,ST8SIA3,RGS7,ATL1,LMO1,ELAVL4" Coexpression Atlas PCBC_SC_1000 Progenitor-Cell-Biology-Consortium_StemCell_top-relative-expression-ranked_1000 PCBC 7.31E-33 3.25E-29 1.05E-30 9.40E-30 122 993 "CDHR1,TMEM74,SYT9,SYNDIG1,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,ACTL6B,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,SLC1A6,LRRC55,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,TMEM151A,SNCB,NMNAT2,JPH4,SALL3,LHFPL4,NAP1L2,NASP,RCOR2,SEPT3,ACSBG1,ABCC8,RHBDL3,PCDH11X,SYT4,GNG3,GNG4,NODAL,UNC5D,CNTN2,KLHL4,GPM6A,GPM6B,GPR19,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,ADAMTS8,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,PCDH8,CDH8,HRH3,TPD52,PCSK2,CA14,CHGA,CHRNB2,NLGN3,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,POU3F4,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,PLD5,IGSF1,FAM131B,RIMS3,DPYSL5,JAKMIP2,CADM2,PTPRD,KCNA6,PTPRO,PTPRZ1,KCNJ11,KCNN3,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,SLC25A18,RET,USH1C,ST8SIA3,RGS7,FGFBP3,LINC00599,RASGRP2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.08E-32 4.80E-29 1.46E-30 1.31E-29 54 193 "MAP6,ACLY,MEG3,EYA1,RTN1,ADCY2,SLITRK1,RXRG,SCN3A,ANK2,ANK3,APC,RUFY2,NSG2,TAGLN3,SNAP25,SCN3B,MYT1L,CADM3,DNER,NCAM1,LMO3,CLASP2,SEPT3,SYT4,GNG3,CAMSAP2,CNTN2,GPM6A,GRIA4,INA,CELF3,PCDH9,RBFOX2,FNDC5,ACOT7,TMEFF2,GDAP1L1,NRXN2,NEGR1,ATCAY,CRMP1,PRKACB,TUBB2B,DNAJC6,JAKMIP2,CEP170,STMN4,L1CAM,EEF1A2,ELAVL3,ELAVL4,BSCL2,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.08E-32 4.80E-29 1.46E-30 1.31E-29 54 193 "MAP6,ACLY,MEG3,EYA1,RTN1,ADCY2,SLITRK1,RXRG,SCN3A,ANK2,ANK3,APC,RUFY2,NSG2,TAGLN3,SNAP25,SCN3B,MYT1L,CADM3,DNER,NCAM1,LMO3,CLASP2,SEPT3,SYT4,GNG3,CAMSAP2,CNTN2,GPM6A,GRIA4,INA,CELF3,PCDH9,RBFOX2,FNDC5,ACOT7,TMEFF2,GDAP1L1,NRXN2,NEGR1,ATCAY,CRMP1,PRKACB,TUBB2B,DNAJC6,JAKMIP2,CEP170,STMN4,L1CAM,EEF1A2,ELAVL3,ELAVL4,BSCL2,EN2" Coexpression Atlas PCBC_ratio_EB_from-mRNA_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-method_mRNA_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.35E-32 5.99E-29 1.71E-30 1.54E-29 66 302 "DPF1,MAPT,APC2,RTN1,ADCYAP1R1,DRAXIN,LINC00461,DISP3,ACTL6B,SEMA6C,ANK2,CNIH2,LRRC55,NSG2,CADPS,GPR153,SCG3,SLIT1,SNAP25,TMEM151A,ATP1A3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,CPLX2,DNER,NFASC,NCAM1,NELL1,SEPT3,RHBDL3,NHLH1,ROBO3,CNTN2,NPPA,BRSK2,FBXL16,INA,CELF3,ZDHHC22,DCLK1,ARHGAP19,FNDC5,ADGRG1,TMEFF2,GDAP1L1,NRXN2,ATCAY,POU3F2,CRMP1,HES5,KIAA0408,TOX,SHD,STMN4,PID1,SLC17A6,FAM57B,L1CAM,ATL1,LINC00599,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas PCBC_ratio_EB_from-OSKM-L_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-reprogram_OSKM-L_vs_Embryoid Body Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.35E-32 5.99E-29 1.71E-30 1.54E-29 66 302 "DPF1,MAPT,APC2,RTN1,ADCYAP1R1,DRAXIN,LINC00461,DISP3,ACTL6B,SEMA6C,ANK2,CNIH2,LRRC55,NSG2,CADPS,GPR153,SCG3,SLIT1,SNAP25,TMEM151A,ATP1A3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,CPLX2,DNER,NFASC,NCAM1,NELL1,SEPT3,RHBDL3,NHLH1,ROBO3,CNTN2,NPPA,BRSK2,FBXL16,INA,CELF3,ZDHHC22,DCLK1,ARHGAP19,FNDC5,ADGRG1,TMEFF2,GDAP1L1,NRXN2,ATCAY,POU3F2,CRMP1,HES5,KIAA0408,TOX,SHD,STMN4,PID1,SLC17A6,FAM57B,L1CAM,ATL1,LINC00599,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.86E-32 8.25E-29 2.29E-30 2.06E-29 121 988 "TTYH1,APC2,MEG3,ADGRV1,IL17D,RTKN,CLIP1,KLHL32,RTN1,SLITRK1,FABP7,TUBB4A,LRRTM4,LINC00461,DISP3,FOXG1,SOX6,SEMA6C,ASRGL1,PPM1E,SHTN1,SLC1A2,MSR1,PKNOX2,ASCL1,PDE8B,SCG3,TAGLN3,DLL3,ASTN1,B3GAT1,SNAP25,ATM,ATP1A3,PHYHIPL,ATP2B2,SOX5,ILDR2,LHFPL4,KIF1B,NPAS3,NASP,FGF17,ACSBG1,RHBDL3,PCDH11X,ASTN2,DCLK2,SEMA4A,GNG3,GNG4,WWC1,CACNA1A,WSCD1,GPM6A,GPM6B,ACSL6,TCF7L2,DIRAS1,HAP1,PTBP2,CAMK2A,CECR2,VSTM2A,PSD3,GRIK2,MFSD2A,INA,TJP1,CELF3,CDK11B,MAGI1,PRMT8,ADGRG1,CA14,TUB,JAM2,NLGN3,SERPINE2,KIAA1549L,NRXN2,SEMA5B,TJP2,CELF5,COL9A2,PRRX1,SPATA6,FAT3,ATCAY,ACBD5,CRMP1,NKAIN4,NCAN,FMN2,IGSF1,CTNND2,MAPK10,HES5,PROX1,BRINP3,ZBTB16,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRD,SRGAP3,KCNN3,BEND5,DTNA,L1CAM,ABCC9,ST8SIA3,RFX4,EFNA3,ELAVL3,ELAVL4,OLIG2,EPB41,LRRC23,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.94E-32 8.60E-29 2.32E-30 2.09E-29 54 195 "MEG3,RTN1,FABP7,AMER2,SCN3A,ANK2,ANK3,APC,NSG2,CADPS,PHYHIPL,DKK3,SCN3B,MYT1L,KIF21B,NMNAT2,DNER,NCAM1,LMO3,GFRA1,SEPT3,SYT4,GNG3,GPM6A,CACNA1E,GRIA2,INA,CELF3,DCLK1,RBFOX2,SEZ6L,PCSK2,TMEFF2,NRXN1,NRXN2,NEGR1,CNTN1,FAT3,POU3F2,CRMP1,NCAN,PRKACB,KIAA0408,DPYSL5,CEP170,STMN4,NTM,DPP6,RALGDS,PAK5,L1CAM,ELAVL3,ELAVL4,EN2" Coexpression Atlas PCBC_EB_fibroblast_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 2.07E-32 9.21E-29 2.42E-30 2.18E-29 84 499 "C1orf194,MAP6,MAPT,ADGRV1,RTN1,RXRG,FABP7,AGT,LINC00461,ACTL6B,HPCAL4,C1orf61,LRRC55,NSG2,DACH2,ASCL1,SCG3,CSPG5,SLIT1,TAGLN3,SLN,B3GAT1,SNAP25,TMEM151A,PHYHIPL,MYT1L,SOX10,ILDR2,ENKUR,CPLX2,DNER,NCAM1,NELL1,NHLH1,SYT4,GNG3,MYRF,CDK5R2,CNTN2,GPM6A,NPPA,CAMK2A,BRSK2,GRIA2,GRIA4,TF,OLR1,GUCY1A1,CELF3,KCNK10,PCDH8,SEZ6L,LGI1,FNDC5,SCRG1,CHGA,GDAP1L1,SEMA5B,FAM181B,CELF5,PRRX1,BTBD17,POU3F2,NKAIN4,ATRNL1,NCAN,RIMS4,PHACTR3,RIMS3,DPYSL5,ITIH2,SHD,STMN4,PTPRD,PTPRO,KCNQ2,TMEM255A,SLC17A6,USH1C,RFX4,LINC00599,ELAVL3,ELAVL4,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 5.46E-32 2.43E-28 6.23E-30 5.59E-29 82 482 "DPF1,TTYH1,APC2,MBP,ADGRV1,RTN1,SLITRK1,ADCYAP1R1,FABP7,TUBB4A,LINC00461,FOXG1,SOX6,FOXM1,ASRGL1,PPM1E,SHTN1,SLC1A2,NSG2,ASCL1,SCG3,TAGLN3,DLL3,B3GAT1,SNAP25,ATP1A3,PHYHIPL,ATP2B2,ILDR2,GAD2,LHFPL4,KIF1B,NPAS3,ACSBG1,DCLK2,ROBO3,GNG3,WSCD1,GPM6A,GPM6B,ACSL6,DDR1,DIRAS1,HAP1,CECR2,GRIK2,GRIK3,MFSD2A,INA,CELF3,CDH8,ADGRG1,CA14,TUB,JAM2,GDAP1L1,NRXN2,SEMA5B,FAM181B,CELF5,ATCAY,POU3F4,CRMP1,NCAN,CTNND2,MAPK10,HES5,PROX1,DPYSL5,TUBB2B,JAKMIP2,ELMO1,STMN4,PTPRZ1,SRGAP3,DTNA,ST8SIA3,RFX4,ELAVL3,ELAVL4,OLIG2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.58E-32 2.92E-28 7.31E-30 6.56E-29 53 191 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,LRRC4C,NSG2,ASCL1,SNAP25,MYT1L,JPH4,TTC9B,DNER,NCAM1,NELL1,GNG3,GPM6A,CACNA1E,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,NXPH1,CRMP1,NCAN,PHACTR3,BRINP3,ANKS1B,CA10,PLPPR1,STMN4,OLIG1,DPP6,PAK5,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.73E-32 3.88E-28 9.24E-30 8.29E-29 62 272 "TTYH1,ABAT,MEG3,ADGRV1,WLS,NDRG2,ADCYAP1R1,FABP7,LINC00461,SEMA6A,C1orf61,APC,BCAN,LRRC4C,SLC1A2,MT3,ASCL1,SCG3,CSPG5,ATP1A2,PHYHIPL,ILDR2,FXYD6,NPAS3,NCAM1,SMOC1,GFAP,HEPN1,NFIA,MLC1,LUZP2,DCLK2,WWC1,GPM6A,GPM6B,CACNB2,GRID1,GRM3,CD81,SEZ6L,ADGRG1,SCRG1,SERPINE2,NRXN1,SEMA5B,FAM181B,PMP2,FAT3,SNCAIP,NKAIN4,NCAN,CTNND2,HES5,MASP1,PTCH1,RGMA,PTPRZ1,PANTR1,DPP6,DTNA,RFX4,FGFBP3" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 8.93E-32 3.97E-28 9.24E-30 8.29E-29 98 684 "DPF1,TTYH1,APC2,MBP,MEG3,ADGRV1,RTN1,FABP7,ERMN,CHST15,LRRTM4,LINC00461,FHL1,FOXG1,SEMA6C,NLGN1,LRRC4C,SHTN1,MADD,ASCL1,TAGLN3,SORCS3,ASTN1,NRG3,PHYHIPL,CADM3,ILDR2,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,WWC1,CACNA1A,WSCD1,GPM6B,FAM69C,ACSL6,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,MFSD2A,PAX6,PCDH9,CDH8,PDE1A,PRMT8,ADGRG1,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,NECAB2,SLC36A4,FAT3,ATCAY,FEZ1,FMN2,IGSF1,MAPK10,HES5,BRINP3,TOX,DPYSL5,TUBB2B,SHD,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX4,RFX5,CACNG7,ELAVL3,ELAVL4,BSCL2,LRRC23" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 8.94E-32 3.97E-28 9.24E-30 8.29E-29 83 497 "TTYH1,APC2,ADGRV1,KLHL32,RTN1,SLITRK1,FABP7,TUBB4A,LRRTM4,LINC00461,FOXG1,SOX6,ASRGL1,PPM1E,SHTN1,SLC1A2,ASCL1,SCG3,TAGLN3,DLL3,ASTN1,B3GAT1,SNAP25,PHYHIPL,ATP2B2,SOX5,ILDR2,LHFPL4,NPAS3,NASP,FGF17,ACSBG1,RHBDL3,PCDH11X,ASTN2,DCLK2,SEMA4A,GNG3,WWC1,WSCD1,GPM6A,GPM6B,ACSL6,TCF7L2,DIRAS1,HAP1,CAMK2A,CECR2,PSD3,GRIK2,INA,CELF3,CDK11B,MAGI1,PRMT8,ADGRG1,CA14,TUB,JAM2,KIAA1549L,NRXN2,SEMA5B,CELF5,FAT3,ATCAY,NCAN,FMN2,IGSF1,CTNND2,MAPK10,HES5,BRINP3,ZBTB16,DPYSL5,JAKMIP2,STMN4,SRGAP3,DTNA,ST8SIA3,RFX4,ELAVL3,ELAVL4,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.63E-31 7.25E-28 1.62E-29 1.46E-28 98 689 "DPF1,TTYH1,ABAT,APC2,CEND1,MEG3,RTN1,SLITRK1,ADCYAP1R1,FABP7,ERMN,CHST15,LRRTM4,FOXG1,SEMA6C,ANK2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,B3GAT1,NRG3,CADM3,LHFPL4,NPAS3,NASP,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,ROBO3,CACNA1A,GPM6B,FAM69C,ACSL6,DIRAS1,AZIN2,CECR2,TMEM151B,VSTM2A,PSD3,AKNA,MFSD2A,PCDH9,CDH8,PRMT8,ADGRG1,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,FEZ1,FMN2,IGSF1,MAPK10,NOS1AP,BRINP3,TOX,SPIRE1,TUBB2B,JAKMIP2,SHD,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas PCBC_SC_blastocyst_1000 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.64E-31 7.30E-28 1.62E-29 1.46E-28 120 996 "RIMKLA,CDHR1,TMEM74,SYT9,SYNDIG1,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,ACTL6B,C1orf61,PDZD4,SH3GL2,PPM1E,SLC1A6,LRRC55,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,ASTN1,B3GAT1,IGSF9B,SNCB,ATP1A2,ATP1A3,PHYHIPL,MEGF11,NMNAT2,JPH4,SALL3,LHFPL4,RCOR2,SEPT3,ACSBG1,ABCC8,RHBDL3,PCDH11X,SYT4,GNG3,GNG4,UNC5D,KLHL4,GPM6A,GPM6B,GPR19,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,GRM3,PTPN5,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,CDH8,HRH3,TPD52,CA14,CHGA,CHRNB2,NLGN3,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CNTN1,CABP1,CELF5,NECAB2,PACSIN1,FAT3,ATCAY,BTBD17,POU3F4,ETNPPL,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,PLD5,IGSF1,RIMS3,DPYSL5,PLPPR5,TUBB2B,ZNF385B,JAKMIP2,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,SLC25A48,CALN1,FAM57B,DPP6,SLC25A18,RET,USH1C,ST8SIA3,RGS7,LMO1,FGFBP3,LINC00599,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.77E-31 7.88E-28 1.71E-29 1.54E-28 72 377 "ZFYVE27,MAP6,RBM10,MEG3,RTN1,AMER2,SCN3A,SOX6,AMPH,ANK2,ANK3,SLC1A2,ARFGAP2,CCDC88A,SHANK2,NSG2,TMEM108,CCDC181,SCN3B,MYT1L,KIF21B,JPH4,DNER,NPAS3,NCAM1,NELL1,PHLDB1,SEPT3,CASTOR3,NKX2-2,CAMTA1,CAMSAP2,CACNA1A,GPM6A,CACNA1E,B4GALNT4,GRIA2,OPCML,INA,TMEM9,NEURL1,PCDH9,CDH8,DCLK1,RBFOX2,DLGAP3,CADM1,NRXN1,NRXN2,NEGR1,CPT1C,CELF5,ATCAY,ACBD5,CRMP1,TENM4,VCAN,NCAN,KIAA0408,LRRTM3,CEP170,STMN4,CDH20,NTM,ARNT2,DPP6,PAK5,L1CAM,SLC4A10,ELAVL3,ELAVL4,EPB41L1" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.00E-31 8.87E-28 1.89E-29 1.69E-28 102 744 "DPF1,TTYH1,APC2,CEND1,MEG3,ADGRV1,RTN1,ADCYAP1R1,FABP7,ERMN,TUBB4A,CHST15,LRRTM4,FOXG1,ANK2,CNIH2,NLGN1,LRRC4C,SHTN1,MADD,NSG2,SCMH1,TAGLN3,SORCS3,ASTN1,SNAP25,NRG3,CADM3,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,WSCD1,GPM6B,FAM69C,ACSL6,DDR1,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,MFSD2A,CELF3,PAX6,PCDH9,CDH8,PDE1A,PRMT8,ADGRG1,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,MFSD4A,POU3F4,FEZ1,FMN2,IGSF1,CTNND2,MAPK10,BRINP3,TOX,DPYSL5,TUBB2B,SHD,STMN4,PTPRD,SV2A,SRGAP3,NTM,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.25E-31 1.44E-27 3.00E-29 2.69E-28 70 359 "TTYH1,ABAT,MAP6,MEG3,ADGRV1,LDLRAD3,WLS,NDRG2,CLIP1,ADCYAP1R1,FABP7,ERMN,LINC00461,SEMA6A,C1orf61,ASRGL1,BCAN,LRRC4C,SLC1A2,ARHGAP5,MT3,ASCL1,CSPG5,CCDC181,ATP1A2,PHYHIPL,SOX5,ILDR2,NPAS3,NCAM1,SMOC1,HEPN1,NFIA,MLC1,DCLK2,WWC1,GPM6A,GPM6B,TCF12,PSD3,SEZ6L,LGI1,ADGRG1,SCRG1,JAM2,SERPINE2,KIAA1549L,PMP2,FAT3,NXPH1,SNCAIP,TENM4,NKAIN4,NCAN,IGSF1,CTNND2,HES5,MASP1,TOX,LRRTM3,PTCH1,LRP8,RGMA,PTPRZ1,PANTR1,DPP6,DTNA,RTN4,RFX4,FGFBP3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 3.30E-31 1.47E-27 3.00E-29 2.69E-28 82 494 "TTYH1,MBP,ADGRV1,KLHL32,RTN1,SLITRK1,FABP7,ERMN,TUBB4A,LINC00461,FOXG1,SOX6,PPM1E,NLGN1,SHTN1,ASCL1,SCG3,DLL3,ASTN1,B3GAT1,ADGRA1,SNAP25,ATP1A3,PHYHIPL,ATP2B2,ILDR2,GAD2,ARPP21,SALL3,LHFPL4,NPAS3,NASP,LMO3,C11orf87,AJAP1,ACSBG1,GNG3,WWC1,GPM6A,GPM6B,CLEC9A,DIRAS1,HAP1,PTBP2,CECR2,GRIK2,MFSD2A,INA,CELF3,CDK11B,PAX6,PCDH9,CDH8,MAGI1,ADGRG1,JAM2,KIAA1549L,NRXN2,SEMA5B,FAM181B,FAT3,ATCAY,POU3F4,NCAN,FMN2,IGSF1,CTNND2,MAPK10,HES5,ZBTB16,TOX,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRZ1,DTNA,RFX4,ELAVL3,ELAVL4,OLIG2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 8.42E-31 3.74E-27 7.49E-29 6.72E-28 79 465 "ZFYVE27,MAP6,RBM10,MEG3,RTN1,AMER2,SCN3A,LINC00461,SOX6,AMPH,ANK2,ANK3,SORBS1,JAKMIP3,SLC1A2,ARFGAP2,CCDC88A,SHANK2,NSG2,TMEM108,CCDC181,SCN3B,MYT1L,KIF21B,JPH4,DNER,NPAS3,NCAM1,NELL1,PHLDB1,SEPT3,CASTOR3,NKX2-2,CAMTA1,CAMSAP2,CACNA1A,GPM6A,CACNA1E,B4GALNT4,BRSK2,GRIA2,OPCML,INA,TMEM9,NEURL1,PCDH9,CDH8,DCLK1,RBFOX2,DLGAP3,CADM1,NRXN1,NRXN2,NEGR1,UBTF,CPT1C,CELF5,ATCAY,ACBD5,CRMP1,TENM4,VCAN,NCAN,KIAA0408,LRRTM3,CEP170,STMN4,CDH20,NTM,ARNT2,DPP6,RTN4,PAK5,L1CAM,BSDC1,SLC4A10,ELAVL3,ELAVL4,EPB41L1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.30E-30 5.80E-27 1.14E-28 1.02E-27 107 830 "MAP6,MAPT,ACHE,APC2,CEND1,EYA1,CSMD3,NDRG2,RTN1,ADCYAP1R1,FABP7,PNMA8B,TUBB4A,CHST15,SCN3A,UNC79,ASRGL1,SGIP1,ANK2,APBA2,APBB1,SLC7A14,NSG2,CADPS,ASCL1,SCG3,TAGLN3,DDX25,ASTN1,SNAP25,ATP1A3,PHYHIPL,SCN3B,CADM3,SOX10,TTC9B,KIF1B,NAP1L2,NFASC,NCAM1,CLASP2,GFRA1,SEPT3,FAM168A,SYT4,ASTN2,CAMTA1,GNG3,GPM6B,B4GALNT4,GPR17,GPR19,HAP1,VSTM2A,GRIA2,GRIA4,INA,CELF3,IGSF21,TNR,PCDH9,DCLK1,ARHGAP19,ACOT7,CHGA,TUB,CHRNB2,TMEFF2,GDAP1L1,SERPINE2,CADM1,NRXN1,SULT4A1,ATCAY,CRMP1,PTPA,FEZ1,SDC3,CMTM5,NRSN1,MAPK10,PROX1,KIAA0408,DPYSL5,TUBB2B,PSMD13,DNAJC6,JAKMIP2,STMN4,KCNA4,PTPRO,PTPRZ1,SV2A,SRGAP3,DLG2,DPP6,RALGDS,L1CAM,CRTAC1,RET,ST8SIA3,RGS7,ATL1,EEF1A2,LMO1,ELAVL4,BSCL2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.68E-30 7.46E-27 1.44E-28 1.29E-27 71 379 "ASIC1,ACLY,RTN3,RTN1,SCN3A,HPCAL4,ANK2,ANK3,SH3GL2,APBB1,APC,NLGN1,SLC1A2,ARHGAP5,NSG2,CADPS,SCG3,SNAP25,FYN,DKK3,SCN3B,B3GALT2,KIF21B,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,NRDC,GRIA2,ATP13A2,INA,CELF3,CDC42,CDH10,RBFOX2,ACOT7,TMEFF2,CADM1,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,FAT3,ATCAY,CRMP1,SDC3,CALY,KIAA0408,TUBB2B,LRRTM3,DNAJC6,JAKMIP2,BDNF-AS,RGMA,STMN4,SV2A,KCNN3,SUSD4,RTN4,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.74E-30 7.71E-27 1.46E-28 1.31E-27 68 347 "TTYH1,EPS8,ABAT,MEG3,ADGRV1,CSMD2,WLS,NDRG2,ADCYAP1R1,FABP7,SCN3A,LINC00461,SEMA6A,C1orf61,BCAN,LRRC4C,SLC1A2,MT3,ASCL1,SCG3,CSPG5,ATP1A2,PHYHIPL,ILDR2,DNER,NPAS3,NCAM1,SMOC1,HEPN1,NFIA,MLC1,LUZP2,DCLK2,PSRC1,WWC1,GPM6A,GPM6B,ZEB1,VXN,OMG,OPCML,SEZ6L,ADGRG1,SCRG1,SERPINE2,PMP2,FAT3,SNCAIP,NKAIN4,NCAN,SDC3,CTNND2,HES5,MASP1,PTCH1,ITGAV,RGMA,PTPRZ1,NTM,PCDH15,PANTR1,OLIG1,DPP6,DTNA,RFX4,FGFBP3,C2orf80,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.11E-30 9.35E-27 1.73E-28 1.56E-27 55 221 "ASIC1,MEG3,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,C1orf61,SGIP1,ANK3,BCAN,LRRC4C,NSG2,ASCL1,CSPG5,SNAP25,MYT1L,SOX10,DNER,NPAS3,NCAM1,GNG3,CACNA1A,GPM6A,TCF12,GRIA2,GRIA4,OPCML,INA,REPS2,PCDH9,CDH8,SCRG1,GDAP1L1,NRXN1,NRXN2,NEGR1,CNTN1,PMP2,NXPH1,CRMP1,PHACTR3,HES5,ANKS1B,STMN4,NTM,OLIG1,DPP6,PAK5,L1CAM,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.83E-30 3.04E-26 5.52E-28 4.95E-27 34 72 "MEG3,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,C1orf61,BCAN,NSG2,ASCL1,CSPG5,MYT1L,SOX10,NCAM1,CACNA1A,GPM6A,GRIA2,GRIA4,OPCML,INA,REPS2,CDH8,SCRG1,GDAP1L1,NRXN2,CNTN1,PMP2,NXPH1,PHACTR3,NTM,OLIG1,ELAVL4,EN2,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.67E-30 3.41E-26 6.08E-28 5.46E-27 69 366 "DPF1,ASIC1,SYNDIG1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,GPR158,SCN3A,LINC00461,ASIC4,C1orf61,TRIM46,SGIP1,ANK3,PI16,SYBU,LRRC4C,NSG2,ASCL1,SCG3,SNAP25,FYN,MYT1L,JPH4,TTC9B,DNER,NCAM1,NELL1,CASTOR3,GNG3,GPM6A,CACNA1E,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,TNS1,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,UBTF,NXPH1,CRMP1,NCAN,PHACTR3,CTNND2,HES5,BRINP3,ANKS1B,CA10,PLPPR1,STMN4,OLIG1,DPP6,ATN1,PAK5,FAM135B,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 8.37E-30 3.72E-26 6.52E-28 5.86E-27 98 723 "DPF1,TTYH1,APC2,CEND1,MEG3,RTN1,ADCYAP1R1,FABP7,ERMN,CHST15,LRRTM4,FOXG1,SEMA6C,ANK2,CNIH2,NTNG1,NLGN1,LRRC4C,SHTN1,MADD,MSR1,SCMH1,ASCL1,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,SOX5,CADM3,JPH4,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,DIRAS1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,GRIK2,MFSD2A,PCDH9,CDH8,PDE1A,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,MFSD4A,NKAIN4,FEZ1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,SHD,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.26E-29 5.60E-26 9.66E-28 8.67E-27 51 193 "MAP6,MEG3,RTN1,AMER2,SCN3A,ANK2,ANK3,SLC1A2,CCDC88A,SHANK2,NSG2,SCN3B,MYT1L,KIF21B,JPH4,DNER,NPAS3,NCAM1,SEPT3,CAMTA1,CAMSAP2,CACNA1A,GPM6A,CACNA1E,B4GALNT4,GRIA2,INA,PCDH9,DCLK1,RBFOX2,CADM1,NRXN1,NRXN2,NEGR1,CELF5,ATCAY,CRMP1,VCAN,NCAN,KIAA0408,CEP170,STMN4,NTM,ARNT2,DPP6,PAK5,L1CAM,SLC4A10,ELAVL3,ELAVL4,EPB41L1" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.32E-29 5.84E-26 9.90E-28 8.89E-27 93 660 "DPF1,TTYH1,ABAT,APC2,CEND1,MEG3,RTN1,FABP7,ERMN,CHST15,LRRTM4,FOXG1,SEMA6C,CDC42BPA,ANK2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,CCDC181,NRG3,CADM3,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,DIRAS1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,MFSD2A,PCDH9,CDH8,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,NECAB2,SLC36A4,FAT3,ATCAY,FEZ1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,SHD,STMN4,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.67E-29 7.40E-26 1.23E-27 1.11E-26 63 307 "MAP6,RTN1,AMER2,SCN3A,ANK2,ANK3,APC,SLC1A2,MADD,NSG2,GPR153,SCG3,TAGLN3,DLL3,SNAP25,DKK3,SCN3B,MYT1L,KIF21B,NMNAT2,DNER,NFASC,NCAM1,LMO3,CLASP2,ARHGEF7,NHLH1,SYT4,GNG3,CNTN2,ADGRL3,GPM6A,ZEB1,GRIA2,INA,CELF3,PAX6,PCDH9,DCLK1,RBFOX2,FNDC5,GDAP1L1,NRXN1,NECAB2,ATCAY,POU3F2,CRMP1,VCAN,CTNND2,MAPK8,KIAA0408,RIMS3,CADM2,STMN4,OLFM3,SV2A,SLC17A6,FAM57B,RALGDS,L1CAM,ELAVL3,ELAVL4,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.16E-29 9.59E-26 1.57E-27 1.41E-26 69 372 "ZFYVE27,MAP6,RBM10,MEG3,RTN1,AMER2,SCN3A,LINC00461,ANK2,ANK3,SORBS1,JAKMIP3,SLC1A2,CCDC88A,SHANK2,NSG2,TMEM108,SCN3B,MYT1L,KIF21B,JPH4,DNER,NPAS3,NCAM1,NELL1,SEPT3,NKX2-2,CAMTA1,CAMSAP2,CACNA1A,GPM6A,CACNA1E,B4GALNT4,BRSK2,GRIA2,OPCML,INA,NEURL1,PCDH9,CDH8,DCLK1,RBFOX2,CADM1,NRXN1,NRXN2,NEGR1,UBTF,CELF5,ATCAY,CRMP1,TENM4,VCAN,NCAN,KIAA0408,LRRTM3,CEP170,STMN4,CDH20,NTM,ARNT2,DPP6,RTN4,PAK5,L1CAM,BSDC1,SLC4A10,ELAVL3,ELAVL4,EPB41L1" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.25E-29 1.44E-25 2.33E-27 2.09E-26 99 749 "DPF1,TTYH1,APC2,CEND1,MEG3,ADGRV1,SLC25A25,RTN1,ADCYAP1R1,FABP7,ERMN,CHST15,LRRTM4,FOXG1,ANK2,NLGN1,LRRC4C,SHTN1,MADD,MSR1,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,SOX5,CADM3,JPH4,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DIRAS1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,GRIK2,MFSD2A,PAX6,PCDH9,CDH8,PDE1A,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,MFSD4A,POU3F4,NKAIN4,FEZ1,ATRNL1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,SHD,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 4.79E-29 2.13E-25 3.38E-27 3.03E-26 51 198 "RTN1,SCN3A,HPCAL4,ANK2,ANK3,APBB1,SLC1A2,NSG2,CADPS,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,DNER,FXYD6,NCAM1,LMO3,CLASP2,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,GRIA2,ATP13A2,INA,CELF3,CDC42,RBFOX2,ACOT7,CADM1,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,SDC3,CALY,KIAA0408,DNAJC6,BDNF-AS,STMN4,SV2A,RTN4,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.11E-28 4.95E-25 7.74E-27 6.94E-26 49 184 "TTYH1,ADGRV1,NDRG2,ADCY2,ADCYAP1R1,FABP7,LINC00461,C1orf61,BCAN,SLC1A2,MT3,SCG3,ATP1A2,DKK3,DNER,SMOC1,GFAP,INKA2,NFIA,MLC1,LUZP2,DCLK2,WWC1,WSCD1,GPM6B,ZEB1,TCF12,PSD3,SEZ6L,ADGRG1,SCRG1,JAM2,SERPINE2,PMP2,FAT3,TENM4,NKAIN4,NCAN,SDC3,HES5,LRP8,PTPRZ1,NTM,PANTR1,OLIG1,DPP6,RFX4,FGFBP3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 200 GSE76381_iPSMoleculeCountsPMLog2 1.23E-28 5.44E-25 8.38E-27 7.52E-26 96 720 "ASIC1,ACLY,RTN3,RTN1,SLITRK1,SCN3A,ACTL6B,HPCAL4,ANK2,ANK3,SH3GL2,APBB1,APC,NLGN1,SLC1A2,SLC7A14,URGCP,ARHGAP5,NSG2,DACH2,CADPS,SCG3,ASTN1,B3GAT1,SNAP25,FYN,DKK3,SCN3B,B3GALT2,KIF21B,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,GFRA1,SEPT3,ARHGEF7,SYT4,GNG3,GNG4,GPM6A,GPM6B,NRDC,GRIA2,ATP13A2,INA,CELF3,KCNK10,CDC42,CDH10,RBFOX2,ACOT7,CHGA,TUB,TMEFF2,CADM1,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,SLC36A4,FAT3,ATCAY,CRMP1,TENM4,SDC3,CALY,KIAA0408,PLPPR5,TUBB2B,LRRTM3,DNAJC6,JAKMIP2,BDNF-AS,CADM2,RGMA,STMN4,PLPPR4,SV2A,KCNN3,SLC17A6,PLEKHB2,ATG16L1,SUSD4,RTN4,BSDC1,RET,ELAVL3,PLEKHO1,PRRT4,EPB41L1,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.55E-28 6.89E-25 1.04E-26 9.37E-26 88 615 "DPF1,TTYH1,APC2,MEG3,ADGRV1,RTN1,ADCYAP1R1,FABP7,CHST15,LRRTM4,FOXG1,SEMA6C,NLGN1,LRRC4C,SHTN1,MADD,SCG3,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,ATP2B2,CADM3,NPAS3,NASP,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,AZIN2,PTBP2,TMEM151B,VSTM2A,PSD3,GRIK2,MFSD2A,CELF3,CDK11B,PCDH9,CDH8,PRMT8,TUB,HPCA,GDAP1L1,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,FEZ1,FMN2,IGSF1,MAPK10,HES5,BRINP3,TOX,TUBB2B,JAKMIP2,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,ELAVL3,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.12E-28 9.44E-25 1.41E-26 1.27E-25 50 195 "TTYH1,ABAT,MEG3,ADGRV1,WLS,NDRG2,ADCYAP1R1,FABP7,LINC00461,SEMA6A,C1orf61,BCAN,LRRC4C,SLC1A2,MT3,ASCL1,CSPG5,ATP1A2,PHYHIPL,ILDR2,NPAS3,NCAM1,SMOC1,HEPN1,NFIA,MLC1,DCLK2,WWC1,GPM6A,GPM6B,SEZ6L,ADGRG1,SCRG1,SERPINE2,PMP2,FAT3,SNCAIP,NKAIN4,NCAN,CTNND2,HES5,MASP1,PTCH1,RGMA,PTPRZ1,PANTR1,DPP6,DTNA,RFX4,FGFBP3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 200 GSE76381_ESMoleculeCountsPMLog2 2.92E-28 1.30E-24 1.91E-26 1.71E-25 96 728 "MAP6,RTN1,AMER2,SCN3A,DISP3,C1orf61,ANK2,ANK3,APBA2,APC,SLC1A2,MADD,RUFY2,NSG2,GPR153,SCG3,TAGLN3,DLL3,B3GAT1,SNAP25,DKK3,SCN3B,MYBPC1,MYT1L,KIF21B,NMNAT2,DNER,NFASC,NCAM1,LMO3,CLASP2,GFRA1,RCOR2,NELL1,NEUROD1,ARHGEF7,NHLH1,OS9,SYT4,GNG3,GNG4,CNTN2,ADGRL3,GPM6A,GPM6B,ZEB1,CECR2,NUMA1,BRSK2,GRIA2,INA,CELF3,PAX6,PCDH9,DCLK1,RBFOX2,FNDC5,ACOT7,ADGRG1,GDAP1L1,NRXN1,CAMKV,SULT4A1,VAV2,NECAB2,ATCAY,POU3F2,CRMP1,NKAIN4,VCAN,NCAN,FMN2,CTNND2,MAPK8,KIAA0408,RIMS3,PSMD13,PTCH1,CADM2,HP1BP3,STMN4,OLFM3,SV2A,AK5,NKAIN1,SLC17A6,FAM57B,RALGDS,L1CAM,CRTAC1,RGS10,CBLN2,ELAVL3,ELAVL4,BSCL2,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.17E-28 1.41E-24 2.04E-26 1.83E-25 65 344 "TTYH1,ABAT,MEG3,ADGRV1,WLS,NDRG2,ADCY2,ADCYAP1R1,FABP7,SORCS1,AGT,LINC00461,SEMA6A,C1orf61,BCAN,LRRC4C,CLSTN1,SLC1A2,ARHGAP5,MT3,ASCL1,PDE8B,CSPG5,ATP1A2,PHYHIPL,DKK3,TNIK,CADM3,ILDR2,ENKUR,NPAS3,NCAM1,SMOC1,HEPN1,NELL1,SEPT3,NFIA,MLC1,DCLK2,WWC1,GPM6A,GPM6B,SEZ6L,ADGRG1,SCRG1,JAM2,SERPINE2,PMP2,FAT3,SNCAIP,NKAIN4,NCAN,CTNND2,HES5,MASP1,PTCH1,PLPPR1,RGMA,PTPRZ1,KCNN3,PANTR1,DPP6,DTNA,RFX4,FGFBP3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.83E-28 1.70E-24 2.43E-26 2.18E-25 67 367 "RTN1,SLITRK1,SCN3A,ACTL6B,HPCAL4,ANK2,ANK3,APBB1,SLC1A2,SLC7A14,URGCP,NSG2,DACH2,CADPS,SCG3,ASTN1,B3GAT1,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,DNER,FXYD6,NCAM1,LMO3,CLASP2,SEPT3,ARHGEF7,SYT4,GNG3,GNG4,GPM6A,GRIA2,ATP13A2,INA,CELF3,KCNK10,CDC42,RBFOX2,ACOT7,CHGA,CADM1,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,TENM4,SDC3,CALY,KIAA0408,DNAJC6,BDNF-AS,CADM2,STMN4,SV2A,SLC17A6,ATG16L1,RTN4,BSDC1,ELAVL3,PLEKHO1,EPB41L1,RCAN2" Coexpression Atlas PCBC_ECTO_fibroblast_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 5.99E-28 2.66E-24 3.75E-26 3.36E-25 114 996 "MAP6,CDHR1,EMID1,TMEM74,ADGRV1,FABP7,ERMN,GRAMD1B,SLC30A10,C1orf61,SESN3,SLITRK3,NLGN1,SLC1A6,BCO1,LRRC55,PKNOX2,SLC8A2,SCG3,SLCO1A2,SLIT1,TAGLN3,DDX25,ASTN1,B3GAT1,ATP1A2,PHYHIPL,SOX1,SOX5,SOX10,ILDR2,SALL3,LHFPL4,LMO3,COLGALT2,STOX1,SMOC1,GPR162,RND1,PCDH11X,NHLH1,SYT4,UNC5D,CNTN2,ADGRL3,PRUNE2,GPM6A,FAM69C,GPR19,CAMK2A,CECR2,GRIA1,GRIA4,GRM3,PTPN5,CELF3,KCNK10,PAX6,IGSF21,PCDH8,CDH8,LGI1,IGFN1,PRMT8,HAPLN2,CA14,ANO5,HPCA,NLGN3,DLGAP3,SULT4A1,CELF5,COL9A2,NECAB2,FAT3,ATCAY,BTBD17,POU3F2,TENM4,NKAIN4,KCNT2,ATRNL1,NCAN,CMTM5,RAB39A,PLD5,USP54,IGSF1,CTNND2,MAPK10,HES5,ZBTB16,RIMS3,DPYSL5,ZNF385B,CA10,CADM2,KCNA1,OLFM3,CDH20,PTPRD,KCNJ4,KCNQ2,HS3ST4,TMEM255A,FAM57B,DPP6,USH1C,RFX4,RLBP1,LMO1,SLC4A10,ELAVL3,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 7.88E-28 3.50E-24 4.86E-26 4.37E-25 113 984 "TTYH1,ACLY,MBP,MEG3,ADGRV1,NDRG2,KLHL32,RTN1,SLITRK1,FABP7,ERMN,TUBB4A,LINC00461,FHL1,HPCAL4,FOXG1,SOX6,CDC42BPA,ANK2,PPM1E,NTNG1,NLGN1,SHTN1,MADD,ASCL1,SCG3,DLL3,ASTN1,B3GAT1,ADGRA1,SNAP25,ATP1A3,PHYHIPL,ATP2B2,SOX5,ILDR2,GAD2,ARPP21,SALL3,LHFPL4,STARD10,ADGRB2,NPAS3,NASP,LMO3,C11orf87,SEPT3,AJAP1,ACSBG1,NFIA,PCDH11X,C1QC,ROBO3,GNG3,WWC1,CACNA1A,GPM6A,GPM6B,CLEC9A,DIRAS1,HAP1,PTBP2,CECR2,GRIK2,TMEM25,MFSD2A,INA,CELF3,CDK11B,PAX6,PCDH9,CDH8,MAGI1,PDE3B,PRMT8,ADGRG1,TUB,JAM2,KIAA1549L,NRXN2,SEMA5B,FAM181B,CELF5,FAT3,ATCAY,POU3F4,CRLS1,FEZ1,NCAN,FMN2,IGSF1,CTNND2,MAPK10,HES5,ZBTB16,TOX,DPYSL5,SPIRE1,TUBB2B,JAKMIP2,PMEPA1,STMN4,PTPRZ1,SRGAP3,RABGAP1L,CCDC3,DTNA,RFX4,ELAVL3,ELAVL4,OLIG2,EPB41,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.57E-27 6.99E-24 9.57E-26 8.59E-25 49 194 "MAP6,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,TUBB4A,SGIP1,ANK2,SLC7A14,CADPS,ASCL1,SCG3,TAGLN3,SNAP25,PHYHIPL,SCN3B,SOX10,NAP1L2,GFRA1,SEPT3,GNG3,GRIA2,INA,CELF3,DCLK1,ACOT7,SCRG1,CHGA,TMEFF2,GDAP1L1,SERPINE2,CADM1,NRXN1,CRMP1,FEZ1,NRSN1,MAPK10,JAKMIP2,STMN4,PTPRZ1,DLG2,L1CAM,RET,RGS7,ATL1,CACNG7,LMO1,ELAVL4" Coexpression Atlas PCBC_SC_fibroblast_1000 Progenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 1.59E-27 7.08E-24 9.57E-26 8.59E-25 113 992 "RIMKLA,CDHR1,TMEM74,SYNDIG1,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,ACTL6B,C1orf61,PDZD4,CNIH2,SH3GL2,PPM1E,BCAN,JAKMIP3,SLC1A6,LRRC55,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,TMEM151A,SNCB,NMNAT2,JPH4,SALL3,LHFPL4,RCOR2,SEPT3,ACSBG1,RHBDL3,PCDH11X,LUZP2,GNG3,GNG4,NODAL,UNC5D,KLHL4,GPM6A,GPM6B,GPR19,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,ADAMTS8,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,CDH8,HRH3,CA14,CHGA,NLGN3,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PLD5,IGSF1,RIMS3,DPYSL5,TUBB2B,LRRTM3,JAKMIP2,CADM2,KCNA6,PTPRZ1,KCNJ11,KCNN3,KCNQ2,NKAIN1,HS3ST4,SLC25A48,CALN1,FAM57B,SLC25A18,RET,USH1C,ST8SIA3,FGFBP3,LINC00599,C2orf80,RASGRP2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.74E-27 7.72E-24 1.03E-25 9.25E-25 66 365 "RTN1,SORCS1,SCN3A,SEMA6A,ELMOD1,HPCAL4,ASRGL1,ANK2,ANK3,APBB1,NLGN1,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,ADGRB2,DNER,FXYD6,NCAM1,BCL2L2,SEPT3,ARHGEF7,SYT4,GNG4,GPM6A,EML4,GRIA2,ATP13A2,OPCML,FBXL16,INA,CELF3,CDC42,IGSF21,DCLK1,RBFOX2,PCSK2,CHGA,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,PRKACB,CTNND2,PROX1,KIAA0408,RIMS3,DPYSL5,DNAJC6,BDNF-AS,CADM2,COPS7A,RGMA,STMN4,PTPRE,SV2A,RTN4,ELAVL3,BSCL2,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 200 GSE76381_iPSMoleculeCountsPMLog2 2.06E-27 9.17E-24 1.21E-25 1.08E-24 80 533 "RBM10,RTN1,SORCS1,SCN3A,SEMA6A,ELMOD1,HPCAL4,ASRGL1,ANK2,ANK3,APBB1,NLGN1,NSG2,SCG3,MTR,RCOR3,SNAP25,FYN,DKK3,SCN3B,WDTC1,KIF21B,NMNAT2,JPH4,ADGRB2,DNER,FXYD6,NASP,NCAM1,BCL2L2,SEPT3,ARHGEF7,SYT4,GNG4,GPM6A,EML4,GRIA2,ATP13A2,OPCML,FBXL16,INA,CELF3,CDC42,IGSF21,PCDH9,DCLK1,RBFOX2,PCSK2,CHGA,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,FAT3,ATCAY,CRMP1,PRKACB,CTNND2,PROX1,KIAA0408,TOX,KIAA0513,RIMS3,DPYSL5,DNAJC6,BDNF-AS,CADM2,COPS7A,RGMA,STMN4,PTPRE,SV2A,NTM,RAD52,RTN4,ELAVL3,BSCL2,EPB41L1,RCAN2" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_500 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 2.88E-27 1.28E-23 1.66E-25 1.49E-24 77 498 "TTYH1,RIMKLA,CEND1,RYR1,FABP7,SCN4B,ACTL6B,HPCAL4,PPM1E,BCAN,NLGN1,LRRC55,SCG3,TMEM151A,SNCB,ATP1A2,ATP1A3,SOX1,NMNAT2,LHFPL4,DNER,NAP1L2,LMO3,ACSBG1,ABCC8,RHBDL3,GNG3,GNG4,CNTN2,ACSL6,TMEM151B,SYT6,GRIA4,GRM3,FBXL16,TLL2,ZDHHC22,PAH,C1orf94,DCLK1,HRH3,CHGA,TMEFF2,GDAP1L1,NRXN1,NRXN2,CAMKV,DNAJC12,ST8SIA5,CABP1,ATCAY,BTBD17,CP,RIMS4,IGSF1,FAM131B,KLK6,TOX,DPYSL5,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRO,PTPRZ1,NTM,AK5,RABGAP1L,KCNMA1,PYGM,FAM57B,RGS7,ATL1,CACNG7,FGFBP3,LINC00599,RASGRP2" Coexpression Atlas Arv_SC-LF_2500_K5 AravindRamakr_StemCell-LF_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 3.61E-27 1.60E-23 2.06E-25 1.85E-24 123 1157 "DPF1,RIMKLA,TMEM74,CEND1,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,DRAXIN,LRRTM4,SEMA6A,HPCAL4,C1orf61,PDZD4,CNIH2,SH3GL2,PPM1E,SLITRK3,JAKMIP3,SLC1A6,LRRC55,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,KIF21B,NMNAT2,JPH4,SALL3,LHFPL4,NAP1L2,NASP,RCOR2,RND1,SEPT3,PCDH11X,LUZP2,GNG3,GNG4,NODAL,UNC5D,WWC1,KLHL4,GPM6B,B4GALNT4,GPR19,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,ADAMTS8,GRM3,PTPN5,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,CDH8,HRH3,PCSK2,CA14,CHGA,PLEKHB1,CHRNB2,HPCA,NLGN3,DLGAP3,GDAP1L1,NRXN1,CAMKV,SEMA5B,SULT4A1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,POU3F4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,PLD5,IGSF1,RIMS3,DPYSL5,TUBB2B,LRRTM3,JAKMIP2,CADM2,PARD6A,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,RET,USH1C,ST8SIA3,JMJD1C,RGS7,ATL1,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas PCBC_ratio_EB UCB CD34+Z_vs_EB blastocyst_cfr-2X-p05 EB UCB CD34+Z_vs_EB blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.90E-27 1.73E-23 2.19E-25 1.97E-24 39 117 "DPF1,APC2,RTN1,CHST15,LINC00461,DISP3,CNIH2,LRRC55,NSG2,GPR153,SCG3,SLIT1,ATP1A3,PHYHIPL,NMNAT2,CPLX2,DNER,NFASC,NCAM1,SEPT3,NHLH1,ROBO3,GNG4,CNTN2,GPM6B,INA,CELF3,DCLK1,ARHGAP19,FNDC5,ADGRG1,GDAP1L1,ATCAY,CTNND2,KIAA0408,STMN4,ATL1,LINC00599,ELAVL3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.31E-27 1.92E-23 2.39E-25 2.15E-24 50 207 "MAP6,RIMKLA,MAPT,RTN1,SLITRK1,SORCS1,SCN3A,C1QTNF4,ANK2,ST8SIA1,SLC7A14,SLC8A3,ASCL1,LGI3,ASPH,ASTN1,SNAP25,SCN3B,TTC9B,DNER,NPAS3,C11orf87,GFRA1,ARHGEF7,PCDH11X,B4GALNT4,GRIA1,INA,CDH10,LGI1,PIRT,TMEFF2,DUSP26,NRXN2,NEGR1,CNTN1,CRMP1,NRSN1,MAPK10,TUBB2B,JAKMIP2,STMN4,PTPRO,KCNK2,KCNQ2,HS3ST4,CALN1,RET,ELAVL3,ELAVL4" Coexpression Atlas Arv_EB-LF_1000 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000 PCBC 5.03E-27 2.23E-23 2.76E-25 2.48E-24 112 990 "SERPINA3,MAPT,SYNDIG1,ADGRV1,CSMD2,RTN1,FABP7,ERMN,AMER2,NLGN4X,AGT,LINC00461,ACTL6B,HPCAL4,C1orf61,PDZD4,CNIH2,CCDC80,LRRC4C,LRRC55,PKNOX2,NSG2,DACH2,SCG3,SLIT1,SLN,B3GAT1,SNAP25,TMEM151A,PHYHIPL,ILDR2,GAD2,ENKUR,ARPP21,CPLX2,DNER,GFAP,NELL1,MLC1,C1QC,SYT4,MYRF,CNTN2,ANO4,GPM6A,CAMK2A,PCDHGA3,TMEM151B,VSTM2A,GRIA1,GRIA2,GRIA4,TF,OLR1,CRB1,SPX,GUCY1A1,CELF3,PAX6,PCDH8,SEZ6L,LGI1,SCRG1,HPSE2,GDAP1L1,FAM181B,CELF5,PRRX1,NECAB2,FAT3,BTBD17,POU3F2,TENM4,NKAIN4,KCNT2,CSF3R,ATRNL1,NCAN,RIMS4,PHACTR3,FMN2,KIAA1755,PLPP4,PLD5,BRINP3,KLK6,PSD,DPYSL5,CA10,PTHLH,SHD,STMN4,OLFM3,CDH20,PTPRO,KCNMA1,KCNQ2,TMEM255A,SLC17A6,FAM57B,DPP6,FAM13C,PAK5,USH1C,RFX4,LINC00599,SLC4A10,ELAVL3,ELAVL4,C2orf80,EN2,SEZ6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.24E-27 2.33E-23 2.84E-25 2.55E-24 101 827 "SERPINA3,PRR5L,MAPT,EYA1,IL17D,RTN1,SLITRK1,ADCYAP1R1,WAC,FABP7,SORCS1,SCN3A,SGIP1,ANK2,NTNG1,ZNF365,SLC7A14,SLC14A1,DACH2,CADPS,ASCL1,SCG3,ASPH,ASTN1,SNAP25,PHYHIPL,ATP2B2,MEGF11,SCN3B,GART,DNER,NAP1L2,NPAS3,C11orf87,GFRA1,ARHGEF7,PCDH11X,SYT4,UNC5D,ADGRL3,ACSL6,B4GALNT4,GPR17,PTBP2,DDR2,BRSK2,GRIA2,GRM3,GUCY1A1,CDC42,PCDH8,CDH10,DCLK1,LGI1,PDE1A,PDE4B,PIRT,TUB,TMEFF2,DUSP26,NLGN3,CADM1,NEGR1,CNTN1,CELF5,BTF3L4,PRRX1,CRMP1,PPP3CB,FEZ1,PHACTR3,FMN2,NRSN1,MAPK10,TOX,LRRTM3,DNAJC6,JAKMIP2,PTHLH,LRP8,CEP170,MAGI2,STMN4,KCNA1,PTPRO,PTPRZ1,KCNK2,KCNQ2,TMEM255A,CALN1,GOPC,FAM13C,ABCC9,SLC6A15,RET,ST8SIA3,ATL1,TTLL7,EFNA3,ABI2,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K2 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 6.04E-27 2.68E-23 3.23E-25 2.90E-24 89 660 "DPF1,TTYH1,APC2,MBP,MEG3,ADGRV1,RTN1,ADCYAP1R1,FABP7,CHST15,LINC00461,FOXG1,SEMA6C,ANK2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,ASCL1,SCG3,TAGLN3,SORCS3,ASTN1,RCOR3,SNAP25,NRG3,GAD2,LHFPL4,NPAS3,NCAM1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,GNG3,CACNA1A,GPM6A,GPM6B,FAM69C,ACSL6,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,GRIK2,MFSD2A,CELF3,PCDH9,CDH8,ADGRG1,TUB,JAM2,HPCA,GDAP1L1,KIAA1549L,SEMA5B,NEGR1,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,FEZ1,FMN2,IGSF1,MAPK10,HES5,BRINP3,TOX,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRD,SV2A,SRGAP3,ARNT2,DTNA,RFX5,ELAVL3,ELAVL4,BSCL2,OLIG2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 7.57E-27 3.36E-23 4.00E-25 3.59E-24 94 731 "DPF1,TTYH1,APC2,MEG3,RTN1,ADCYAP1R1,FABP7,ERMN,CHST15,LRRTM4,LINC00461,FOXG1,CDC42BPA,ANK2,CNIH2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,SOX5,CADM3,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,DIRAS1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,MFSD2A,PCDH9,CDH8,PDE1A,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,MFSD4A,FEZ1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,SHD,STMN4,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,EFNA3,ELAVL3,BSCL2,LRRC23" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.27E-26 5.64E-23 6.64E-25 5.96E-24 93 722 "DPF1,TTYH1,ABAT,APC2,MEG3,RTN1,ADCYAP1R1,FABP7,CHST15,LRRTM4,LINC00461,FOXG1,SEMA6C,ANK2,CNIH2,NLGN1,LRRC4C,SHTN1,MADD,SCMH1,TAGLN3,SORCS3,ASTN1,RCOR3,NRG3,SOX5,CADM3,LHFPL4,NPAS3,NCAM1,LMO3,GFRA1,SEPT3,FAM168A,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,FAM69C,ACSL6,DDR1,DIRAS1,AZIN2,TMEM151B,VSTM2A,PSD3,AKNA,MFSD2A,PCDH9,CDH8,PRMT8,TUB,JAM2,HPCA,NLGN3,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,CPT1C,FLRT1,CCDC136,CELF5,SLC25A27,SLC36A4,FAT3,ATCAY,MFSD4A,FEZ1,FMN2,IGSF1,MAPK10,BRINP3,TOX,TUBB2B,SHD,STMN4,PTPRD,PTPRZ1,SV2A,SRGAP3,ARNT2,KCNN3,DTNA,RFX5,CACNG7,PIANP,ELAVL3,BSCL2,LRRC23" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.31E-26 5.81E-23 6.76E-25 6.07E-24 70 424 "MAPT,EYA1,IL17D,RTN1,SLITRK1,WAC,FABP7,SORCS1,SCN3A,SGIP1,ANK2,NTNG1,ZNF365,SLC7A14,SLC14A1,DACH2,CADPS,ASCL1,ASPH,ASTN1,SNAP25,SCN3B,DNER,NAP1L2,NPAS3,C11orf87,GFRA1,ARHGEF7,PCDH11X,SYT4,UNC5D,ACSL6,GPR17,BRSK2,GRM3,CDH10,DCLK1,LGI1,PDE4B,PIRT,TMEFF2,DUSP26,NLGN3,NEGR1,CNTN1,PRRX1,CRMP1,FEZ1,FMN2,NRSN1,MAPK10,TOX,LRRTM3,DNAJC6,JAKMIP2,LRP8,MAGI2,STMN4,KCNA1,PTPRZ1,KCNK2,KCNQ2,CALN1,FAM13C,ABCC9,SLC6A15,RET,ST8SIA3,TTLL7,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 1.50E-26 6.65E-23 7.65E-25 6.86E-24 76 498 "TTYH1,RTN3,ADGRV1,CLIP1,KLHL32,RTN1,ADCYAP1R1,FABP7,TUBB4A,LINC00461,FHL1,FOXG1,SOX6,NLGN1,SLC1A2,ASCL1,SCG3,DLL3,B3GAT1,SNAP25,ATP1A3,PHYHIPL,ATP2B2,ILDR2,SALL3,NPAS3,NASP,LMO3,AJAP1,WWC1,WSCD1,GPM6A,GPM6B,HAP1,PTBP2,CECR2,GRIK2,GRIK4,INA,CELF3,CDK11B,PAX6,CDH8,PRMT8,ADGRG1,JAM2,HPCA,CADM1,KIAA1549L,NRXN2,SEMA5B,FAM181B,FAT3,ATCAY,POU3F4,PLCH2,FMN2,CTNND2,MAPK10,HES5,PROX1,MASP1,ZBTB16,DPYSL5,TUBB2B,JAKMIP2,STMN4,PTPRZ1,SRGAP3,KCNN3,RFX4,EFNA3,ELAVL3,ELAVL4,OLIG2,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 2.22E-26 9.86E-23 1.12E-24 1.01E-23 62 336 "MAP6,RTN1,SCN3A,DISP3,C1orf61,ANK2,ANK3,APBA2,GPR153,SCG3,TAGLN3,DLL3,B3GAT1,MYBPC1,KIF21B,NMNAT2,DNER,NFASC,NCAM1,CLASP2,RCOR2,NELL1,ARHGEF7,NHLH1,SYT4,GNG3,GNG4,CNTN2,GPM6B,ZEB1,CECR2,NUMA1,BRSK2,INA,CELF3,RBFOX2,FNDC5,ADGRG1,GDAP1L1,VAV2,NECAB2,ATCAY,POU3F2,CRMP1,NKAIN4,NCAN,FMN2,CTNND2,MAPK8,RIMS3,HP1BP3,STMN4,NKAIN1,SLC17A6,FAM57B,RALGDS,L1CAM,CRTAC1,CBLN2,ELAVL3,ELAVL4,EPB41" Coexpression Atlas ratio_EB_vs_SC_2500_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 2.45E-26 1.09E-22 1.22E-24 1.10E-23 118 1102 "EPS8,C1orf194,MAP6,ASIC1,APC2,WLS,RTN1,AMER2,SCN3A,LINC00461,ACTL6B,SOX6,SGIP1,CNIH2,NTNG1,MAGI3,CCDC80,LRRC4C,ST8SIA1,SLC1A2,PKNOX2,NSG2,DACH2,ASCL1,SLIT1,TAGLN3,SORCS3,ADGRA1,SNAP25,TMEM151A,PHYHIPL,SCN3B,MYT1L,SOX5,ZCCHC24,SOX10,ILDR2,ENKUR,NKX6-2,TTLL9,TTC9B,CPLX2,DNER,NPAS3,GFRA1,NELL1,RGL1,KIRREL3,GJB1,NEUROD1,NHLH1,SYT4,DCLK2,MYRF,CDK5R2,CNTN2,TBX15,GPM6A,ZEB1,AZIN2,DDR2,GRIA1,GRIA2,GRID1,GRIK2,TF,OLR1,OMG,CRB1,TGFBR3,CELF3,KCNK10,DAAM2,PAX6,PCDH8,CDH10,SEZ6L,LGI1,PDE1A,SCRG1,HPSE2,CASC2,TMEFF2,CADM1,NEGR1,FLRT1,FAM181B,COL9A2,PRRX1,POU3F2,TENM4,NKAIN4,FMN2,CALY,PLPP4,MAPK10,HES5,MASP1,PSD,DPYSL5,ITIH2,STMN4,KCNA2,CDH20,PTPRO,CCDC3,DNAH9,TMEM255A,SLC17A6,FAM13C,RFX4,SLC39A12,CBLN2,ELAVL3,ELAVL4,EN2,RPE65,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.53E-26 1.12E-22 1.25E-24 1.12E-23 64 359 "MEG3,RTN1,FABP7,AMER2,SCN3A,SOX6,ANK2,ANK3,APC,CLSTN1,NSG2,CADPS,PHYHIPL,DKK3,SCN3B,MYT1L,KIF21B,NMNAT2,DNER,NCAM1,LMO3,GFRA1,SEPT3,SYT4,GNG3,GPM6A,CACNA1E,GRIA2,INA,CELF3,DCLK1,RBFOX2,SEZ6L,PCSK2,TUB,TMEFF2,NRXN1,NRXN2,NEGR1,CNTN1,BTF3L4,IFFO1,FAT3,POU3F2,CRMP1,RGS6,NCAN,PRKACB,KIAA0408,DPYSL5,CEP170,STMN4,PTPRZ1,NTM,DPP6,RALGDS,PAK5,L1CAM,FAM135B,PIANP,ELAVL3,ELAVL4,EN2,RCAN2" Coexpression Atlas ratio_SC_vs_MESO_1000_K5 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.82E-26 1.25E-22 1.38E-24 1.24E-23 79 541 "TTYH1,RIMKLA,CEND1,CSMD2,ADCYAP1R1,RYR1,FABP7,TUBB4A,DRAXIN,ACTL6B,HPCAL4,CNIH2,PPM1E,BCAN,NLGN1,LRRC55,SCG3,CSPG5,IGSF9B,SNCB,SOX1,NMNAT2,JPH4,LHFPL4,NAP1L2,LMO3,RHBDL3,GNG3,GNG4,CACNA1A,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRM3,FBXL16,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,DCLK1,HRH3,CHGA,CHRNB2,GDAP1L1,NRXN1,NRXN2,CAMKV,ATCAY,BTBD17,POU3F4,CRMP1,RIMS4,IGSF1,FAM131B,ECE2,TOX,DPYSL5,PHYHIP,LRRTM3,JAKMIP2,OLFM3,PARD6A,PTPRZ1,NTM,RABGAP1L,KCNN3,KCNQ2,FAM57B,ST8SIA3,RGS7,ATL1,CACNG7,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.11E-26 1.38E-22 1.50E-24 1.35E-23 62 338 "TTYH1,ABAT,MEG3,ADGRV1,WLS,NDRG2,ADCYAP1R1,FABP7,LINC00461,SEMA6A,C1orf61,BCAN,LRRC4C,SLC1A2,MT3,ASCL1,CSPG5,ATP1A2,PHYHIPL,ILDR2,MIR4697HG,NPAS3,NCAM1,SMOC1,GFAP,INKA2,HEPN1,NFIA,MLC1,DCLK2,WWC1,WSCD1,GPM6A,GPM6B,SEZ6L,ADGRG1,SCRG1,SERPINE2,CADM1,TJP2,PMP2,FAT3,SNCAIP,NKAIN4,NCAN,SDC3,CTNND2,HES5,MASP1,PTCH1,PRDM2,RGMA,STMN4,PTPRZ1,SV2A,PANTR1,OLIG1,DPP6,DTNA,RFX4,FGFBP3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.93E-26 1.75E-22 1.86E-24 1.67E-23 48 198 "RTN1,SCN3A,ANK2,ANK3,APBB1,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,SEPT3,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,INA,CELF3,DCLK1,ACOT7,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,RIMS4,CALY,KIAA0408,RIMS3,DNAJC6,JAKMIP2,BDNF-AS,CEP170,STMN4,SV2A,RTN4,ELAVL3,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.93E-26 1.75E-22 1.86E-24 1.67E-23 48 198 "RTN1,SCN3A,HPCAL4,ANK2,ANK3,APBB1,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,DNER,FXYD6,NCAM1,SEPT3,ARHGEF7,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,FBXL16,INA,CELF3,CDC42,DCLK1,RBFOX2,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,PRKACB,CTNND2,KIAA0408,RIMS3,DPYSL5,DNAJC6,CADM2,STMN4,SV2A,RTN4,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas Arv_SC-HD_1000_K1 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 5.23E-26 2.33E-22 2.45E-24 2.20E-23 80 559 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SEMA6A,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,JPH4,SALL3,LHFPL4,SEPT3,PCDH11X,GNG3,GNG4,UNC5D,KLHL4,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CA14,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,KCNT2,ATRNL1,RIMS4,RAB39A,IGSF1,RIMS3,DPYSL5,TUBB2B,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,FAM57B,DPP6,RET,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.32E-26 2.81E-22 2.92E-24 2.62E-23 110 989 "DPF1,TTYH1,ACLY,APC2,RTN3,ACTN2,ADGRV1,CLIP1,KLHL32,RTN1,SLITRK1,ADCYAP1R1,FABP7,TUBB4A,LINC00461,FHL1,FOXG1,SOX6,PPM1E,NLGN1,SLC1A2,BCO1,PKNOX2,CCDC88A,NSG2,ASCL1,SCG3,SLCO1A2,TAGLN3,DLL3,ASTN1,B3GAT1,ADGRA1,SNAP25,CCDC181,ATP1A3,PHYHIPL,ATP2B2,ILDR2,SALL3,NPAS3,NASP,LMO3,AJAP1,ARHGEF7,PCDH11X,ROBO3,GNG3,WWC1,CACNA1A,WSCD1,GPM6A,GPM6B,ACSL6,TCF7L2,DIRAS1,HAP1,PTBP2,CECR2,RFFL,GRIK2,GRIK4,MFSD2A,INA,CELF3,CDK11B,PAX6,CDH8,MAGI1,PRMT8,ADGRG1,JAM2,HPCA,CADM1,KIAA1549L,NRXN2,SEMA5B,FLRT1,FAM181B,FAT3,ATCAY,POU3F4,CRMP1,PLCH2,NCAN,FMN2,CTNND2,MAPK10,HES5,PROX1,MASP1,ZBTB16,TOX,DPYSL5,TUBB2B,JAKMIP2,LRP8,STMN4,SMG7,PTPRZ1,SRGAP3,NAV2,KCNN3,KIF2A,RFX4,EFNA3,ELAVL3,ELAVL4,OLIG2,PRRT4" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 6.93E-26 3.08E-22 3.17E-24 2.85E-23 53 248 "APC2,ADGRV1,RTN1,SLITRK1,CHST15,LRRTM4,FHL1,FOXG1,NLGN1,SHTN1,TAGLN3,ASTN1,NRG3,PHYHIPL,ILDR2,NPAS3,NASP,LMO3,RHBDL3,ASTN2,SEMA4A,GNG3,ACSL6,TCF7L2,HAP1,VSTM2A,PSD3,GRIK2,MFSD2A,CELF3,PAX6,PCDH9,CDH8,PRMT8,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,ATCAY,CRMP1,FEZ1,NCAN,FMN2,MAPK10,HES5,BRINP3,TOX,DPYSL5,JAKMIP2,LRP8,PTPRZ1,DTNA" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 7.19E-26 3.19E-22 3.26E-24 2.93E-23 71 448 "TTYH1,ABAT,APC2,MBP,MEG3,ADGRV1,RTN1,SLITRK1,FABP7,CHST15,LRRTM4,LINC00461,FOXG1,SEMA6C,ANK2,SHTN1,ASCL1,TAGLN3,SORCS3,RCOR3,SNAP25,NRG3,ATP2B2,SOX5,CADM3,GAD2,LHFPL4,NPAS3,SEPT3,FAM168A,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,GPM6A,GPM6B,FAM69C,ACSL6,DIRAS1,HAP1,AZIN2,TMEM151B,VSTM2A,PSD3,GRIK2,MFSD2A,CELF3,ADGRG1,TUB,NLGN3,CPT1C,CELF5,SLC25A27,SLC36A4,ATCAY,POU3F4,NCAN,MAPK10,HES5,BRINP3,DPYSL5,SHD,STMN4,SV2A,SRGAP3,ARNT2,DTNA,RFX5,ELAVL3,OLIG2" Coexpression Atlas Arv_EB-LF_1000_K4 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 7.30E-26 3.25E-22 3.28E-24 2.94E-23 70 436 "ADGRV1,RTN1,AMER2,LINC00461,ACTL6B,HPCAL4,C1orf61,CNIH2,LRRC4C,LRRC55,PKNOX2,NSG2,DACH2,SLIT1,SNAP25,TMEM151A,PHYHIPL,ILDR2,GAD2,ENKUR,ARPP21,CPLX2,DNER,NELL1,SYT4,MYRF,CNTN2,ANO4,GPM6A,VSTM2A,GRIA2,TF,OLR1,CRB1,CELF3,PAX6,PCDH8,SEZ6L,LGI1,SCRG1,HPSE2,GDAP1L1,FAM181B,CELF5,NECAB2,POU3F2,TENM4,NKAIN4,ATRNL1,NCAN,PLPP4,BRINP3,PSD,DPYSL5,CA10,STMN4,OLFM3,CDH20,PTPRO,TMEM255A,SLC17A6,DPP6,FAM13C,PAK5,USH1C,RFX4,SLC4A10,ELAVL3,ELAVL4,EN2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.62E-26 4.28E-22 4.28E-24 3.84E-23 49 211 "MAP6,CEND1,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,SORCS1,CHST15,SCN3A,UNC79,SGIP1,ANK2,APBA2,SLC7A14,NSG2,CADPS,SCG3,SNAP25,SCN3B,CADM3,NMNAT2,NCAM1,GFRA1,SEPT3,SYT4,GPR19,GRIA2,GRIK2,INA,PCDH9,DCLK1,TMEFF2,SERPINE2,CADM1,NRXN1,CRMP1,FEZ1,NRSN1,MAPK10,PROX1,TUBB2B,DNAJC6,JAKMIP2,STMN4,DLG2,L1CAM,RET,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.24E-25 5.49E-22 5.44E-24 4.88E-23 64 369 "ASIC1,RTN1,PNMA8B,SCN3A,ANK2,ANK3,APBB1,SYBU,SHANK2,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,SEPT3,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,INA,CELF3,PCDH9,DCLK1,ACOT7,ADGRG1,TUB,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,RIMS4,PRKAB2,CALY,KIAA0408,FGFR1OP2,RIMS3,DNAJC6,JAKMIP2,BDNF-AS,CADM2,PRDM2,CEP170,STMN4,SV2A,NTM,SLC17A6,DSCAM,RTN4,PIANP,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 200 GSE76381_iPSMoleculeCountsPMLog2 1.78E-25 7.91E-22 7.75E-24 6.96E-23 86 650 "MAP6,CSMD2,RTN1,SNX30,TUBB4A,SCN3A,LRRTM4,ACTL6B,GOLGA7B,HPCAL4,ANK2,ANK3,APBB1,DGKD,ST8SIA1,NBPF1,CCDC88A,NSG2,SCG3,SNAP25,DKK3,SCN3B,MYT1L,KIF21B,CADM3,NMNAT2,KIF1B,DNER,FXYD6,NPAS3,NCAM1,CLASP2,SEPT3,ARHGEF7,CASTOR3,SYT4,DDHD2,GNG3,CAMSAP2,CACNA1A,GPM6A,VSTM2A,GRIA2,GRIA4,ATP13A2,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,NTSR2,ADGRG1,CHGA,NRXN1,NEGR1,DNAJC12,CNTN1,MEAF6,CELF5,CRMP1,PRKACB,PRKCZ,SLC45A1,CTNND2,KIAA0408,DPYSL5,DNAJC6,ELMO1,LRP8,MAGI2,STMN4,SV2A,RABGAP1L,RAB5B,RALGDS,C12orf4,RAP1GAP,RTN4,TTLL7,EEF1A2,EFNA3,CBLN2,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.92E-25 8.53E-22 8.28E-24 7.44E-23 40 136 "ASIC1,MEG3,RTN1,SCN3A,LINC00461,APC,SYBU,NSG2,SCG3,TAGLN3,MYT1L,KIF21B,GAD2,NKX6-2,DNER,NCAM1,NEUROD1,SEPT3,NHLH1,SYT4,CNTN2,GPM6A,ZEB1,TCF12,GRIA2,INA,PCDH9,RBFOX2,FNDC5,ADGRG1,GDAP1L1,NEGR1,CELF5,NCAN,PLPPR1,PANTR1,ELAVL3,ELAVL4,EN2,EPB41" Coexpression Atlas Arv_SC-LF_1000_K3 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 2.06E-25 9.16E-22 8.81E-24 7.91E-23 88 679 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,LRRTM4,SEMA6A,ACTL6B,C1orf61,PDZD4,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,SNCB,JPH4,SALL3,LHFPL4,SEPT3,PCDH11X,GNG3,GNG4,NODAL,UNC5D,KLHL4,GPM6A,GPM6B,GPR19,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,GRM3,PTPN5,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,PRMT8,CA14,CHGA,PLEKHB1,CHRNB2,DLGAP3,GDAP1L1,CAMKV,SEMA5B,CELF5,PACSIN1,ATCAY,BTBD17,POU3F4,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,IGSF1,RIMS3,TUBB2B,JAKMIP2,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.30E-25 1.02E-21 9.71E-24 8.72E-23 64 373 "ASIC1,ADGRV1,RTN1,SCN3A,ANK2,ANK3,APBB1,SYBU,SHANK2,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,DCAF5,SEPT3,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,INA,CELF3,PCDH9,DCLK1,ACOT7,ADGRG1,TUB,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,RIMS4,PRKAB2,CALY,KIAA0408,RIMS3,DNAJC6,JAKMIP2,BDNF-AS,CADM2,PRDM2,CEP170,STMN4,SV2A,NTM,DSCAM,RTN4,VANGL2,PIANP,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000_K2 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 5.46E-25 2.43E-21 2.27E-23 2.04E-22 55 279 "APC2,MBP,ADGRV1,RTN1,CHST15,LRRTM4,LINC00461,FOXG1,NLGN1,SHTN1,ASCL1,SCG3,TAGLN3,ASTN1,SNAP25,NRG3,PHYHIPL,ILDR2,NPAS3,RHBDL3,SEMA4A,GNG3,GPM6A,GPM6B,HAP1,VSTM2A,PSD3,GRIK2,MFSD2A,CELF3,PAX6,PCDH9,CDH8,ADGRG1,GDAP1L1,KIAA1549L,NRXN1,SEMA5B,NEGR1,FEZ1,FMN2,CTNND2,MAPK10,HES5,BRINP3,TOX,DPYSL5,JAKMIP2,LRP8,STMN4,DTNA,ELAVL3,ELAVL4,OLIG2,EPB41" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000 FaceBase_RNAseq 5.48E-25 2.43E-21 2.27E-23 2.04E-22 108 984 "APC2,EMID1,MBP,LGR4,ACTN2,ADGRV1,EYA1,IL17D,NDRG2,F3,RTN1,ADCY2,ERMN,TUBB4A,CHST15,LRRTM4,LINC00461,FOXG1,ANK3,DOCK10,NTNG1,CCDC80,NLGN1,SHTN1,SLC1A2,SLC6A9,ASCL1,SCG3,TAGLN3,ASTN1,SNAP25,NRG3,ATP1A3,PHYHIPL,ILDR2,GAD2,JPH4,ARPP21,STARD10,ADGRB2,NPAS3,FGF17,NFIA,RHBDL3,PCDH11X,C1QC,SEMA4A,GNG3,ADGRL3,WWC1,WSCD1,GPM6A,GPM6B,HAP1,CECR2,VSTM2A,PSD3,GRIK2,MFSD2A,INA,CELF3,PAX6,REPS2,PCDH9,CDH8,TPD52,PDE1A,ADGRG1,CA14,GDAP1L1,CADM1,KIAA1549L,NRXN1,SEMA5B,NEGR1,TJP2,FLRT1,NECAB2,NXPH1,FEZ1,PLCH2,FMN2,CTNND2,MAPK10,HES5,BRINP3,TOX,DPYSL5,JAKMIP2,PMEPA1,CADM2,LRP8,STMN4,CCDC3,KCNK1,PCDH15,NAV2,DLG2,SUSD4,DTNA,EFNA3,VWA5A,RAVER2,ELAVL3,ELAVL4,OLIG2,EPB41,EPB41L1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.12E-25 2.72E-21 2.52E-23 2.26E-22 97 819 "MAP6,RIMKLA,MAPT,MEG3,EYA1,CLIP1,RTN1,SLITRK1,SORCS1,SCN3A,KIAA1109,C1QTNF4,SGIP1,ANK2,ANK3,APC,NTNG1,DGKD,ST8SIA1,SHTN1,SLC7A14,SLC8A3,DACH2,ASCL1,CGREF1,LGI3,ASPH,ASTN1,SNAP25,DKK3,SCN3B,SON,AHCYL1,TTC9B,KIF1B,DNER,NPAS3,NASP,C11orf87,CLASP2,GFRA1,RGL1,NFIA,ARHGEF7,PCDH11X,CAMSAP2,ADGRL3,B4GALNT4,GRIA1,GRIA2,FBXL16,INA,ZFP91,CDH10,DCLK1,RBFOX2,LGI1,PIRT,TMEFF2,DUSP26,NRXN2,NEGR1,CNTN1,PRRX1,FAT3,CNRIP1,MED1,CRMP1,TENM4,VCAN,FMN2,NRSN1,MAPK8,MAPK10,PUM1,TUBB2B,LRRTM3,DNAJC6,JAKMIP2,PTHLH,STMN4,KCNA6,PTPRO,PTPRZ1,NTM,ARNT2,KCNK2,KCNMA1,KCNQ2,KIF2A,HS3ST4,CALN1,FAM13C,NUP214,RET,ELAVL3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 9.35E-25 4.15E-21 3.78E-23 3.39E-22 46 193 "MAP6,MEG3,RTN1,AMER2,SCN3A,ANK2,ANK3,APC,SYBU,SLC1A2,NSG2,CADPS,SCG3,TAGLN3,SORCS3,PHYHIPL,KIF21B,NMNAT2,NCAM1,CLASP2,SEPT3,GNG3,GPM6A,GRIA2,INA,DCLK1,RBFOX2,PCSK2,GDAP1L1,NRXN1,ATCAY,CRMP1,NCAN,MAPK8,KIAA0408,TOX,DPYSL5,TUBB2B,CEP170,STMN4,ARNT2,PANTR1,SLC17A6,L1CAM,ELAVL3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.35E-25 4.15E-21 3.78E-23 3.39E-22 46 193 "MAP6,MEG3,RTN1,AMER2,SCN3A,ANK2,ANK3,APC,SYBU,SLC1A2,NSG2,CADPS,SCG3,TAGLN3,SORCS3,PHYHIPL,KIF21B,NMNAT2,NCAM1,CLASP2,SEPT3,GNG3,GPM6A,GRIA2,INA,DCLK1,RBFOX2,PCSK2,GDAP1L1,NRXN1,ATCAY,CRMP1,NCAN,MAPK8,KIAA0408,TOX,DPYSL5,TUBB2B,CEP170,STMN4,ARNT2,PANTR1,SLC17A6,L1CAM,ELAVL3,ELAVL4" Coexpression Atlas PCBC_ratio_SC_vs_DE_500 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 2.16E-24 9.58E-21 8.63E-23 7.75E-22 73 499 "TTYH1,CEND1,RYR1,SCN4B,ACTL6B,ELMOD1,HPCAL4,SLITRK3,BCAN,LRRC55,CGREF1,TMEM151A,ATP1A2,ATP1A3,KIF21B,JPH4,CPLX2,DNER,LMO3,ALDH1L1,INKA2,RND1,SEPT3,SLCO1C1,ACSBG1,ABCC8,RHBDL3,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRIN1,TLL2,ZDHHC22,PAH,TNFRSF1B,HRH3,CHGA,CHRNB2,NLGN3,NRXN2,CAMKV,ST8SIA5,VAV2,CNTN1,CABP1,BTBD17,POU3F4,SNCAIP,NKAIN4,RIMS4,RAB39A,SLC45A1,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRO,NTM,AK5,KCNMA1,KCNN3,PYGM,SUSD4,ATL1,ARHGEF10L,CACNG7,FGFBP3,LINC00599,RASGRP2,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.45E-24 1.09E-20 9.74E-23 8.74E-22 43 170 "MAP6,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,TUBB4A,SGIP1,ANK2,SLC7A14,NSG2,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,TTC9B,NCAM1,GNG3,GRIA2,GRIA4,INA,CELF3,PCDH9,DCLK1,TMEFF2,GDAP1L1,CADM1,NRXN1,CRMP1,FEZ1,NRSN1,MAPK10,PROX1,DPYSL5,JAKMIP2,STMN4,PTPRZ1,DLG2,L1CAM,RET,ATL1,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.69E-24 1.19E-20 1.06E-22 9.48E-22 62 366 "RBM10,RTN1,SCN3A,HPCAL4,ANK2,ANK3,APBB1,NSG2,SCG3,MTR,RCOR3,SNAP25,FYN,DKK3,SCN3B,WDTC1,KIF21B,NMNAT2,JPH4,DNER,FXYD6,NASP,NCAM1,SEPT3,ARHGEF7,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,FBXL16,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,FAT3,ATCAY,CRMP1,PRKACB,CTNND2,KIAA0408,TOX,KIAA0513,RIMS3,DPYSL5,DNAJC6,CADM2,STMN4,SV2A,NTM,RAD52,RTN4,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.00E-24 1.33E-20 1.15E-22 1.03E-21 46 198 "MAP6,RTN1,SCN3A,ANK2,ANK3,APBB1,SHTN1,NSG2,SCG3,SNAP25,ATP1A3,DKK3,SCN3B,KIF21B,NMNAT2,DNER,NCAM1,CLASP2,SEPT3,ARHGEF7,SYT4,GPM6A,ATP13A2,INA,CELF3,CDC42,SEZ6L,ACOT7,GDAP1L1,NRXN1,CNTN1,CRMP1,PRKACB,CTNND2,KIAA0408,CADM2,CEP170,STMN4,KCNMA1,SLC17A6,FAM57B,BSDC1,CBLN2,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE76381_iPSMoleculeCountsPMLog2 3.00E-24 1.33E-20 1.15E-22 1.03E-21 46 198 "MAP6,RTN1,SCN3A,ANK2,ANK3,APBB1,SHTN1,NSG2,SCG3,SNAP25,ATP1A3,DKK3,SCN3B,KIF21B,NMNAT2,DNER,NCAM1,CLASP2,SEPT3,ARHGEF7,SYT4,GPM6A,ATP13A2,INA,CELF3,CDC42,SEZ6L,ACOT7,GDAP1L1,NRXN1,CNTN1,CRMP1,PRKACB,CTNND2,KIAA0408,CADM2,CEP170,STMN4,KCNMA1,SLC17A6,FAM57B,BSDC1,CBLN2,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k1_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.00E-24 1.33E-20 1.15E-22 1.03E-21 48 217 "MAPT,CSMD3,RTN1,SLITRK1,FABP7,SCN3A,ANK2,ST8SIA1,SLC7A14,NSG2,CADPS,ASCL1,SCG3,ASPH,ASTN1,SNAP25,SCN3B,KIF1B,DNER,NPAS3,C11orf87,ARHGEF7,SYT4,VSTM2A,BRSK2,GRIA1,INA,CDC42,CDH10,LGI1,TMEFF2,DUSP26,CADM1,NEGR1,CNTN1,CRMP1,NRSN1,MAPK10,JAKMIP2,CEP170,STMN4,PTPRO,KCNQ2,CALN1,SLC6A15,ST8SIA3,ELAVL3,ELAVL4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.74E-24 1.66E-20 1.42E-22 1.27E-21 54 279 "MAPT,EYA1,CSMD3,RTN1,FABP7,PNMA8B,CHST15,SCN3A,UNC79,SGIP1,ANK2,APBA2,CADPS,SCG3,DDX25,SNAP25,PHYHIPL,SCN3B,KIF1B,NAP1L2,NFASC,NCAM1,CLASP2,GFRA1,SEPT3,SYT4,CAMTA1,HAP1,GRIA2,GRIA4,INA,PCDH9,TUB,SERPINE2,CADM1,NRXN1,CRMP1,NRSN1,MAPK10,PROX1,KIAA0408,DNAJC6,JAKMIP2,STMN4,KCNA4,PTPRZ1,SV2A,SRGAP3,DLG2,L1CAM,RET,ST8SIA3,RGS7,ELAVL4" Coexpression Atlas Arv_SC_fibroblast_1000_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 3.81E-24 1.69E-20 1.44E-22 1.29E-21 77 556 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SEMA6A,PDZD4,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,JPH4,SALL3,LHFPL4,SEPT3,PCDH11X,GNG3,GNG4,UNC5D,KLHL4,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CA14,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,CELF5,PACSIN1,ATCAY,BTBD17,KCNT2,ATRNL1,RIMS4,RAB39A,IGSF1,RIMS3,TUBB2B,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,RET,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas BM Top 100 - subthalamic nucleus BM Top 100 - subthalamic nucleus Body Map 4.24E-24 1.88E-20 1.58E-22 1.42E-21 29 68 "MAG,MBP,PAQR6,ERMN,AMER2,FGF1,MOBP,MOG,BCAS1,AQP4,SLCO1A2,GFAP,NKX2-2,MYRF,CNTN2,CNDP1,VXN,TF,OLR1,SPX,HAPLN2,PLEKHB1,ANLN,PMP2,P2RY12,CMTM5,KLK6,OLIG1,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.39E-24 2.40E-20 1.98E-22 1.78E-21 61 359 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,LRRC4C,NSG2,ASCL1,SNAP25,MYT1L,JPH4,TTC9B,GART,DNER,NCAM1,NELL1,GNG3,GPM6A,CACNA1E,VSTM2A,GRIA2,GRIA4,OPCML,SPX,PTPN5,INA,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,NXPH1,CRMP1,NCAN,PHACTR3,MASP1,BRINP3,ANKS1B,PLPPR5,CA10,PLPPR1,PMEPA1,STMN4,OLIG1,DPP6,RALGDS,PAK5,L1CAM,VWA5A,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.40E-24 2.40E-20 1.98E-22 1.78E-21 38 131 "MAP6,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,SLC7A14,CADPS,SCG3,DDX25,SNAP25,PHYHIPL,SCN3B,CADM3,TTC9B,NCAM1,GFRA1,SEPT3,ASTN2,GRIA2,INA,DCLK1,LGI1,TMEFF2,GDAP1L1,SERPINE2,CADM1,CRMP1,FEZ1,NRSN1,MAPK10,DPYSL5,STMN4,SV2A,DLG2,L1CAM,RET,ELAVL4" Coexpression Atlas PCBC_SC_CD34+_1000 Progenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_1000 PCBC 8.81E-24 3.91E-20 3.21E-22 2.88E-21 106 987 "RIMKLA,CDHR1,TMEM74,SYNDIG1,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,TMEM151A,SNCB,KIF21B,NMNAT2,JPH4,SALL3,LHFPL4,DNER,RND1,SEPT3,ACSBG1,ABCC8,PCDH11X,SYT4,LUZP2,GNG4,NODAL,WWC1,GPM6A,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,TPD52,CA14,CHGA,CHRNB2,DLGAP3,GDAP1L1,NRXN1,CAMKV,SEMA5B,A2ML1,ST8SIA5,SULT4A1,CABP1,CELF5,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,CHD5,NCAN,RIMS4,RAB39A,PRKCG,PLD5,IGSF1,RIMS3,TUBB2B,JAKMIP2,CADM2,PLPPR4,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,RET,USH1C,ST8SIA3,FGFBP3,LINC00599,RASGRP2,SEZ6" Coexpression Atlas Arv_EB-LF_2500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.24E-23 5.51E-20 4.48E-22 4.02E-21 104 960 "MAP6,EXTL1,CSMD2,RTN1,AMER2,SCN3A,LINC00461,ACTL6B,HPCAL4,C1orf61,AMPH,CNIH2,CCDC80,LRRC4C,ZNF365,LRRC55,PKNOX2,NSG2,DACH2,ASCL1,SLIT1,TAGLN3,SNAP25,PHYHIPL,MYT1L,SOX5,ILDR2,GAD2,ENKUR,CPLX2,DNER,GFRA1,NELL1,GJB1,NHLH1,SYT4,GNG3,MYRF,CDK5R2,CNTN2,ADGRL3,GPM6A,DDR2,VSTM2A,GRIA1,GRIA2,GRIK2,TF,OLR1,CRB1,CELF3,KCNK10,DAAM2,PAX6,PCDH8,CDH8,CDH10,SEZ6L,LGI1,PDE1A,SCRG1,HPSE2,TMEFF2,GDAP1L1,CADM1,FLRT1,FAM181B,PRRX1,NECAB2,POU3F2,POU3F4,SNCAIP,TENM4,NKAIN4,MICAL2,ATRNL1,NCAN,FMN2,PLPP4,CTNND2,MASP1,PSD,SYTL2,DPYSL5,CA10,STMN4,OLFM3,CDH20,PTPRD,PLPPR4,PTPRO,KCNK2,KCNMA1,DNAH9,TMEM255A,SLC17A6,PAK5,USH1C,RFX4,SLC4A10,ELAVL3,ELAVL4,EN2,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.00E-23 8.90E-20 7.12E-22 6.39E-21 45 197 "DPF1,MEG3,RTN1,TUBB4A,SCN3A,HPCAL4,ANK2,NSG2,SCN3B,JPH4,FXYD6,NCAM1,SEPT3,GNG3,CACNA1A,GPM6A,B4GALNT4,GRIA1,GRIA2,GRIA4,INA,PCDH9,DCLK1,ACOT7,CADM1,NRXN1,NRXN2,NEGR1,DNAJC12,CNTN1,ATCAY,CRMP1,PRKACB,KIAA0408,PLPPR5,DNAJC6,STMN4,PTPRD,NTM,ARNT2,L1CAM,EEF1A2,ELAVL3,SEZ6,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.00E-23 8.90E-20 7.12E-22 6.39E-21 45 197 "DPF1,MEG3,RTN1,TUBB4A,SCN3A,HPCAL4,ANK2,NSG2,SCN3B,JPH4,FXYD6,NCAM1,SEPT3,GNG3,CACNA1A,GPM6A,B4GALNT4,GRIA1,GRIA2,GRIA4,INA,PCDH9,DCLK1,ACOT7,CADM1,NRXN1,NRXN2,NEGR1,DNAJC12,CNTN1,ATCAY,CRMP1,PRKACB,KIAA0408,PLPPR5,DNAJC6,STMN4,PTPRD,NTM,ARNT2,L1CAM,EEF1A2,ELAVL3,SEZ6,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.43E-23 1.08E-19 8.58E-22 7.71E-21 62 381 "MAP6,RTN1,SCN3A,GOLGA7B,HPCAL4,ANK2,ANK3,ST8SIA1,NBPF1,CCDC88A,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,CADM3,NMNAT2,DNER,NCAM1,CLASP2,SEPT3,ARHGEF7,SYT4,DDHD2,GNG3,CAMSAP2,GPM6A,VSTM2A,GRIA2,GRIA4,ATP13A2,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,CHGA,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,CRMP1,PRKACB,CTNND2,KIAA0408,DNAJC6,ELMO1,LRP8,STMN4,SV2A,RALGDS,C12orf4,RAP1GAP,RTN4,TTLL7,CBLN2,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500 facebase_RNAseq_e10.5_Emin_MedNas_2500 Gudmap RNAseq 2.71E-23 1.21E-19 9.49E-22 8.52E-21 131 1415 "DPF1,TTYH1,MAP6,RIMKLA,MAPT,ACHE,SYT9,EXTL1,CEND1,ADGRV1,MRVI1,ARID1A,CLIP1,RTN1,DSCAML1,WAC,FABP7,SORCS1,ADORA1,TUBB4A,LRRTM4,FHL1,ELMOD1,SOX6,SELL,SFPQ,ANK2,USP28,SH3GL2,PPM1E,APC,NLGN1,ST8SIA1,BCAS1,MADD,PKNOX2,ARHGAP5,CCDC88A,DACH2,CADPS,CSPG5,SLIT1,TAGLN3,CAPRIN2,ASTN1,SMARCE1,SNAP25,ATM,NRG3,PHYHIPL,SCN3B,SOX5,CADM3,ADGRB2,NASP,INKA2,RCOR2,SEPT3,ACSBG1,ARHGEF7,CAMTA1,GNG3,CACNA1A,WSCD1,GPM6A,GPM6B,ZEB1,CLEC9A,GPR19,TCF12,PTBP2,CAMK2A,CECR2,BRSK2,GRIK2,SHISA7,USP2,MFSD2A,GUCY1A2,CELF3,CDK11B,TNFRSF1B,PDE3B,PRMT8,ADGRG1,CA14,JAM2,HPCA,ARHGAP22,KIAA1549L,NRXN1,SEMA5B,PIK3CD,FAM181B,SPATA6,NSD2,FAT3,CP,CRMP1,CSF3R,FEZ1,PLCH2,DOCK7,CTNND2,MAPK8,PROX1,FGFR1OP2,MASP1,ZBTB16,TOX,DPYSL5,ANKS1B,TUBB2B,LRRTM3,PTCH1,DNAJC6,LRP8,KCNC1,PTPRO,PTPRZ1,SRGAP3,ARNT2,NKAIN1,KIF2A,DPP6,DTNA,L1CAM,SFXN5,LMO1,ELAVL4,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.01E-23 1.34E-19 1.05E-21 9.38E-21 56 313 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,SLITRK3,LRRC4C,NSG2,ASCL1,SNAP25,MYT1L,JPH4,TTC9B,DNER,NCAM1,NELL1,GNG3,GPM6A,CACNA1E,TCF12,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,NXPH1,CRMP1,NCAN,PHACTR3,HES5,BRINP3,ANKS1B,CA10,PLPPR1,STMN4,OLIG1,DPP6,PAK5,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas PCBC_SC_blastocyst_500 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 3.93E-23 1.75E-19 1.35E-21 1.21E-20 71 497 "RIMKLA,CDHR1,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,C1orf61,PDZD4,SH3GL2,PPM1E,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,SALL3,LHFPL4,SEPT3,ACSBG1,ABCC8,PCDH11X,SYT4,GNG4,UNC5D,GPM6A,GPM6B,CECR2,TMEM151B,SYT6,GRIA4,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CELF5,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,PTPRZ1,KCNQ2,NKAIN1,CALN1,FAM57B,DPP6,ST8SIA3,FGFBP3,LINC00599,SEZ6" Coexpression Atlas PCBC_EB_blastocyst_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 4.43E-23 1.97E-19 1.51E-21 1.36E-20 71 498 "C1orf194,MAPT,ADGRV1,RXRG,FABP7,AGT,LINC00461,SLC1A6,LRRC55,SLC8A3,NSG2,DACH2,ASCL1,SCG3,SLIT1,B3GAT1,SNAP25,TMEM151A,PHYHIPL,SOX1,SOX10,ILDR2,ENKUR,CPLX2,NCAM1,NELL1,GJB1,NHLH1,SYT4,MYRF,CNTN2,GPM6A,GRIA2,GRIA4,TF,OLR1,GUCY1A1,CELF3,PAH,KCNK10,PAX6,PCDH8,LGI1,SCRG1,GDAP1L1,FLRT1,FAM181B,CELF5,PRRX1,NECAB2,BTBD17,POU3F2,POU3F4,NKAIN4,KCNT2,ATRNL1,PHACTR3,DPYSL5,ITIH2,STMN4,PTPRD,PTPRO,KCNQ2,DNAH9,TMEM255A,DPP6,USH1C,RFX4,CBLN2,ELAVL3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 5.68E-23 2.52E-19 1.93E-21 1.73E-20 61 375 "MAP6,CSMD2,RTN1,SNX30,SCN3A,LRRTM4,ACTL6B,HPCAL4,ANK2,ANK3,APBB1,DGKD,NSG2,SCG3,SNAP25,DKK3,SCN3B,MYT1L,KIF21B,NMNAT2,DNER,FXYD6,NPAS3,NCAM1,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,GRIA2,ATP13A2,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,ADGRG1,NRXN1,NEGR1,DNAJC12,CNTN1,MEAF6,CELF5,CRMP1,PRKACB,PRKCZ,KIAA0408,DNAJC6,MAGI2,STMN4,SV2A,RAB5B,RALGDS,RTN4,EEF1A2,EFNA3,CBLN2,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas Arv_SC-HD_2500_K2 AravindRamakr_StemCell-HD_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 6.31E-23 2.80E-19 2.12E-21 1.91E-20 113 1125 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SEMA6A,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,JAKMIP3,SLC1A6,BCO1,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,TMEM108,IGSF9B,SNCB,MEGF11,KIF21B,NMNAT2,JPH4,SALL3,LHFPL4,NAP1L2,FXYD6,SEPT3,RHBDL3,PCDH11X,GNG3,GNG4,UNC5D,KLHL4,GPM6B,GPR19,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,ADAMTS8,GRM3,PTPN5,TLL2,ZDHHC22,PAH,KCNK10,IGSF21,PADI2,C1orf94,CDH8,HRH3,CA14,CHGA,HPCA,NLGN3,DLGAP3,GDAP1L1,NRXN1,CAMKV,SEMA5B,SULT4A1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,POU3F4,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,IGSF1,NOS1AP,RIMS3,DPYSL5,PLPPR5,TUBB2B,JAKMIP2,CADM2,PTPRD,KCNA6,PARD6A,PTPRZ1,KCNN3,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,RET,USH1C,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE76381_iPSMoleculeCountsPMLog2 7.59E-23 3.37E-19 2.54E-21 2.28E-20 67 451 "ASIC1,ADGRV1,RTN1,PNMA8B,SCN3A,ANK2,ANK3,APBB1,SYBU,SHANK2,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,CADM3,NMNAT2,JPH4,DNER,FXYD6,NCAM1,LMO3,CLASP2,DCAF5,SEPT3,SYT4,GNG4,GPM6A,GRIA2,ATP13A2,INA,CELF3,PCDH9,DCLK1,ACOT7,ADGRG1,TUB,NRXN1,DNAJC12,CNTN1,CELF5,ATCAY,CRMP1,RIMS4,PRKAB2,CALY,KIAA0408,FGFR1OP2,RIMS3,DNAJC6,JAKMIP2,BDNF-AS,CADM2,PRDM2,CEP170,STMN4,SV2A,NTM,SLC17A6,DSCAM,RTN4,VANGL2,PIANP,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.32E-22 5.84E-19 4.36E-21 3.91E-20 44 196 "RTN1,SCN3A,HPCAL4,ANK2,ANK3,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,DNER,NCAM1,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,GRIA2,ATP13A2,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,CRMP1,PRKACB,KIAA0408,DNAJC6,STMN4,SV2A,RALGDS,RTN4,CBLN2,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.53E-22 6.79E-19 5.02E-21 4.51E-20 60 370 "RTN1,SCN3A,HPCAL4,ANK2,ANK3,APBB1,SLC1A2,NSG2,CADPS,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,DNER,FXYD6,NCAM1,LMO3,CLASP2,GFRA1,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,GPM6B,GRIA2,ATP13A2,INA,CELF3,CDC42,RBFOX2,ACOT7,TUB,CADM1,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,SLC36A4,ATCAY,CRMP1,SDC3,CALY,KIAA0408,PLPPR5,DNAJC6,BDNF-AS,STMN4,PLPPR4,SV2A,PLEKHB2,RTN4,RET,ELAVL3,PRRT4,EPB41L1,RCAN2" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.54E-22 6.83E-19 5.02E-21 4.51E-20 103 976 "EPS8,APC2,EMID1,ACTN2,ADGRV1,IL17D,NDRG2,RTN1,ADCY2,SLITRK1,ERMN,TUBB4A,CHST15,LRRTM4,FHL1,MOBP,FOXG1,DOCK10,NTNG1,CCDC80,NLGN1,SHTN1,SLC1A2,SLC6A9,TAGLN3,ASTN1,TMEM108,NRG3,PHYHIPL,ILDR2,JPH4,ARPP21,SALL3,ADGRB2,NPAS3,NASP,LMO3,AJAP1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,ROBO3,GNG3,UNC5D,ADGRL3,WWC1,WSCD1,ACSL6,TCF7L2,HAP1,CECR2,VSTM2A,PSD3,GRIK2,MFSD2A,INA,CELF3,PAX6,REPS2,PCDH9,CDH8,PDE1A,PRMT8,CA14,CADM1,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,FLRT1,NECAB2,ATCAY,NXPH1,CRMP1,FEZ1,NCAN,FMN2,MAPK10,HES5,BRINP3,ZBTB16,TOX,DPYSL5,CA10,JAKMIP2,PMEPA1,CADM2,LRP8,CDH20,PTPRZ1,CCDC3,KCNK1,PCDH15,DLG2,DTNA,ST8SIA3,VWA5A,EPB41L1,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.74E-22 7.72E-19 5.64E-21 5.06E-20 59 359 "MAP6,RTN1,SNX30,TUBB4A,SCN3A,HPCAL4,ANK2,ANK3,NSG2,SCG3,SNAP25,DKK3,SCN3B,KIF21B,NMNAT2,KIF1B,DNER,FXYD6,NCAM1,SEPT3,ARHGEF7,CASTOR3,SYT4,GNG3,CACNA1A,GPM6A,VSTM2A,GRIA2,ATP13A2,INA,CELF3,CDC42,PCDH9,DCLK1,RBFOX2,NTSR2,CHGA,NRXN1,NEGR1,DNAJC12,CNTN1,CELF5,CRMP1,PRKACB,SLC45A1,CTNND2,KIAA0408,DPYSL5,DNAJC6,STMN4,SV2A,RABGAP1L,RALGDS,RAP1GAP,RTN4,CBLN2,ELAVL3,EPB41L1,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-22 9.69E-19 6.97E-21 6.26E-20 22 38 "FABP7,LINC00461,C1orf61,BCAN,MT3,SCG3,ZCCHC24,SOX10,LUZP2,GPM6A,ADGRG1,SCRG1,SERPINE2,CNTN1,PMP2,NKAIN4,HES5,PTPRZ1,NTM,PCDH15,OLIG1,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-22 9.69E-19 6.97E-21 6.26E-20 22 38 "FABP7,LINC00461,C1orf61,BCAN,MT3,SCG3,ZCCHC24,SOX10,LUZP2,GPM6A,ADGRG1,SCRG1,SERPINE2,CNTN1,PMP2,NKAIN4,HES5,PTPRZ1,NTM,PCDH15,OLIG1,OLIG2" Coexpression Atlas PCBC_ECTO_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_1000 PCBC 2.28E-22 1.01E-18 7.24E-21 6.50E-20 104 997 "SDE2,MAP6,EMID1,TMEM74,SYT9,ADGRV1,FAM43B,WLS,FABP7,C1QTNF4,SLC30A10,C1orf61,SESN3,SLITRK3,NLGN1,SLC1A6,BCO1,LRRC55,PKNOX2,SLC8A2,SCG3,SLCO1A2,SLIT1,TAGLN3,DDX25,ASTN1,KBTBD12,B3GAT1,ATP1A2,PHYHIPL,SOX1,SOX10,ILDR2,SALL3,LHFPL4,TTLL9,LMO3,COLGALT2,STOX1,SMOC1,GPR162,PCDH11X,NHLH1,DCLK2,UNC5D,CNTN2,ADGRL3,PRUNE2,GPM6A,FAM69C,CAMK2A,CECR2,VXN,GRIA1,GRIA4,GRM3,PTPN5,CELF3,KCNK10,PAX6,IGSF21,PCDH8,CDH8,LGI1,IGFN1,FNDC5,HAPLN2,CA14,ANO5,NLGN3,CELF5,COL9A2,NECAB2,FAT3,ATCAY,BTBD17,POU3F2,NKAIN4,KCNT2,NCAN,CMTM5,RAB39A,PLD5,ARHGEF4,CTNND2,MAPK10,HES5,RIMS3,DPYSL5,PLPPR5,TUBB2B,ZNF385B,CADM2,STMN4,KCNA1,OLFM3,PTPRD,KCNQ2,TMEM255A,FAM57B,RFX4,RLBP1,ELAVL3,ELAVL4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.01E-22 1.78E-18 1.26E-20 1.13E-19 45 211 "MAP6,MAPT,CEND1,CSMD3,RTN1,ADCYAP1R1,PNMA8B,ACTL6B,UNC79,APBA2,APBB1,SLC7A14,NSG2,DDX25,ASTN1,CADM3,TTC9B,NFASC,NCAM1,GFRA1,SEPT3,ASTN2,HAP1,FBXL16,INA,PCDH9,DCLK1,GDAP1L1,SERPINE2,SULT4A1,CRMP1,FEZ1,NRSN1,MAPK10,PROX1,DPYSL5,TUBB2B,DNAJC6,STMN4,KCNA4,SV2A,SRGAP3,RALGDS,L1CAM,RET" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.28E-22 1.90E-18 1.34E-20 1.20E-19 92 818 "MAPT,EYA1,CSMD3,RTN1,SLITRK1,FABP7,SORCS1,SCN3A,LRRTM4,KIAA1109,SGIP1,ANK2,APC,NTNG1,ST8SIA1,SHTN1,SLC7A14,RUFY2,NSG2,DACH2,CADPS,ASCL1,SCG3,ASPH,ASTN1,SNAP25,DKK3,SCN3B,SOX5,AHCYL1,KIF1B,DNER,NAP1L2,NPAS3,C11orf87,CLASP2,GFRA1,NFIA,ARHGEF7,PCDH11X,SYT4,CAMSAP2,ADGRL3,PTBP2,VSTM2A,BRSK2,GRIA1,GRIA2,GRM3,INA,ZFP91,CDC42,CDH10,DCLK1,RBFOX2,LGI1,TMEFF2,DUSP26,NLGN3,CADM1,NEGR1,CNTN1,CELF5,PRRX1,FAT3,CRMP1,VCAN,RBPJ,DZIP3,CTNND2,NRSN1,MAPK8,MAPK10,TOX,LRRTM3,DNAJC6,JAKMIP2,LRP8,CEP170,STMN4,PTPRO,ARNT2,KCNK2,KCNMA1,KCNQ2,CALN1,FAM13C,SLC6A15,RET,ST8SIA3,ELAVL3,ELAVL4" Coexpression Atlas Arv_SC-hpx_blastocyst_2500_K2 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 4.79E-22 2.13E-18 1.49E-20 1.34E-19 101 959 "RIMKLA,CDHR1,TMEM74,ADGRV1,CSMD2,ADCY2,SLITRK1,GALNT13,RYR1,FABP7,NLGN4X,LRRTM4,SEMA6A,UNC79,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,BCAN,JAKMIP3,SLC1A6,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,NMNAT2,JPH4,SALL3,LHFPL4,RCOR2,RND1,SEPT3,PCDH11X,GNG4,UNC5D,WWC1,KLHL4,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,TLL2,ZDHHC22,PAH,IGSF21,PADI2,C1orf94,HRH3,CA14,CHGA,NLGN3,DLGAP3,GDAP1L1,CAMKV,SEMA5B,SULT4A1,CABP1,CELF5,NECAB2,FAT3,ATCAY,BTBD17,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,DPYSL5,PLPPR5,TUBB2B,LRRTM3,JAKMIP2,CADM2,RABGAP1L,KCNQ2,NKAIN1,HS3ST4,SLC25A48,CALN1,FAM57B,DPP6,SLC25A18,RET,USH1C,FGFBP3,LINC00599,BSCL2,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.58E-22 2.92E-18 2.03E-20 1.82E-19 102 979 "DPF1,TTYH1,APC2,MBP,RTN3,ADGRV1,ECSIT,CLIP1,RTN1,SLITRK1,ADCYAP1R1,WAC,FABP7,TUBB4A,LINC00461,FOXG1,SOX6,FOXM1,ASRGL1,PKP4,PPM1E,APBB1,SHTN1,SLC1A2,MIER1,BCO1,NSG2,ASCL1,SCG3,TAGLN3,DLL3,B3GAT1,SNAP25,ATP1A3,FYN,PHYHIPL,ATP2B2,ILDR2,GAD2,SALL3,LHFPL4,ADAM15,KIF1B,NPAS3,ACSBG1,DCLK2,ROBO3,GNG3,GOLGB1,WWC1,WSCD1,GPM6A,GPM6B,ACSL6,DDR1,ZEB1,DIRAS1,HAP1,CECR2,GRIK2,GRIK3,MFSD2A,INA,CELF3,CD81,HPS5,CDH8,ADGRG1,CA14,TUB,JAM2,GDAP1L1,NRXN2,SEMA5B,FAM181B,CELF5,ATCAY,POU3F4,CRMP1,NCAN,CTNND2,MAPK10,HES5,PROX1,DPYSL5,TUBB2B,LRRTM3,JAKMIP2,ELMO1,STMN4,C1orf109,PTPRZ1,SRGAP3,DTNA,ZYG11B,ST8SIA3,RFX4,RBM12,ELAVL3,ELAVL4,OLIG2,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.87E-22 3.50E-18 2.41E-20 2.16E-19 86 735 "MAP6,CNTNAP3,CEND1,EYA1,CSMD3,NDRG2,RTN1,ADCYAP1R1,FABP7,SORCS1,TUBB4A,CHST15,SCN3A,KIAA1109,LRRC7,FGF14,UNC79,SGIP1,ANK2,APBA2,SLC7A14,NSG2,CADPS,ASCL1,SCG3,TAGLN3,SNAP25,PALLD,GABBR1,SCN3B,CADM3,NMNAT2,NCAM1,GFRA1,NELL1,SEPT3,C1QC,SYT4,ASTN2,GNG3,ADGRL3,CACNA1E,GPR19,DDR2,GRIA1,GRIA2,GRIK2,TF,INA,CELF3,TNR,PCDH9,DCLK1,ACOT7,HPSE2,TMEFF2,GDAP1L1,SERPINE2,CADM1,NRXN1,PRRX1,FAT3,CRMP1,NKAIN4,FEZ1,ATRNL1,VCAN,CMTM5,NRSN1,MAPK10,PROX1,MASP1,TUBB2B,DNAJC6,JAKMIP2,STMN4,KCNMA1,DLG2,TMEM255A,L1CAM,ABCC9,RET,INSYN2,ATL1,LMO1,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.80E-22 4.36E-18 2.96E-20 2.66E-19 27 67 "MEG3,RTN1,FABP7,SCN3A,C1orf61,BCAN,LRRC4C,NSG2,ASCL1,CSPG5,MYT1L,NPAS3,NCAM1,GPM6A,GRIA2,GRIA4,INA,PCDH9,NRXN1,NRXN2,ANKS1B,NTM,OLIG1,SLC4A10,ELAVL4,EN2,OLIG2" Coexpression Atlas BM Top 100 - corpus callosum BM Top 100 - corpus callosum Body Map 9.80E-22 4.36E-18 2.96E-20 2.66E-19 27 67 "MAG,MBP,PAQR6,ERMN,AMER2,FGF1,MOBP,FOXG1,MOG,FOLH1,AQP4,GFAP,NKX2-2,MYRF,CNTN2,CNDP1,VXN,GRM3,TF,SPX,ANLN,OPALIN,P2RY12,KLK6,ANKS1B,OLIG1,OLIG2" Coexpression Atlas PCBC_ECTO_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 1.08E-21 4.78E-18 3.23E-20 2.90E-19 69 499 "MAP6,TMEM74,ADGRV1,FABP7,SLC30A10,C1orf61,SESN3,SLC1A6,BCO1,PKNOX2,SCG3,SLCO1A2,TAGLN3,DDX25,ASTN1,B3GAT1,PHYHIPL,SOX1,ILDR2,SALL3,LHFPL4,LMO3,STOX1,SMOC1,GPR162,PCDH11X,NHLH1,UNC5D,PRUNE2,GPM6A,FAM69C,CAMK2A,CECR2,GRM3,CELF3,KCNK10,PAX6,IGSF21,CDH8,LGI1,PRMT8,HAPLN2,CA14,CELF5,NECAB2,BTBD17,POU3F2,NKAIN4,KCNT2,NCAN,RAB39A,PLD5,CTNND2,HES5,RIMS3,DPYSL5,ZNF385B,CA10,CADM2,KCNA1,OLFM3,PTPRD,KCNQ2,TMEM255A,FAM57B,RFX4,RLBP1,SLC4A10,ELAVL4" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500 facebase_RNAseq_e10.5_NeuroEpith_central_2500 Gudmap RNAseq 1.41E-21 6.26E-18 4.20E-20 3.77E-19 139 1622 "DPF1,TTYH1,ZFYVE27,MAP6,RIMKLA,MAPT,MBP,SYT9,RTN3,CEND1,MEG3,ADGRV1,ARID1A,RTKN,CLIP1,RTN1,WAC,FABP7,SORCS1,TUBB4A,LRRTM4,FHL1,SOX6,FOXM1,AMPH,ASRGL1,CDC42BPA,ANK2,USP28,PPM1E,APC,ST3GAL3,ST8SIA1,SHTN1,ZNF365,RUFY2,PKNOX2,YPEL4,CCDC88A,CADPS,SLIT1,TAGLN3,CAPRIN2,ASTN1,SNAP25,ATM,NRG3,PHYHIPL,MEGF11,SCN3B,SOX5,KIF21B,CADM3,KIF1B,NASP,INKA2,RCOR2,SEPT3,ACSBG1,ARHGEF7,DCLK2,SEMA4A,CAMTA1,GNG3,MYRF,PSRC1,WWC1,CACNA1A,WSCD1,GPM6A,GPM6B,CACNB2,TCF7L2,ZEB1,GPR19,TCF12,HAP1,AZIN2,PTBP2,CAMK2A,CECR2,BRSK2,PSD3,GRIK2,SHISA7,USP2,MFSD2A,GUCY1A2,CELF3,CDK11B,DCLK1,MAGI1,PDE1C,PRMT8,ADGRG1,CA14,TMEFF2,JAM2,ARHGAP22,NLGN3,CADM1,KIAA1549L,NRXN1,SEMA5B,SLC25A27,SPATA6,NSD2,FAT3,CRMP1,NKAIN4,KCNT2,FEZ1,DOCK7,CTNND2,PROX1,BRINP3,ZBTB16,DPYSL5,TUBB2B,PTCH1,LRP8,SHD,PTPRZ1,SRGAP3,ARNT2,NKAIN1,KIF2A,DTNA,L1CAM,RFX5,PHC2,VANGL2,RBM12,LMO1,ARHGAP12,ELAVL4,ROM1,PLEKHO1,EPB41" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.45E-21 6.45E-18 4.30E-20 3.86E-19 57 350 "TTYH1,APC2,ADGRV1,MDM4,SLC25A25,RTN1,SLITRK1,FABP7,LINC00461,FOXG1,ASRGL1,APBB1,SHTN1,NSG2,ASCL1,TAGLN3,DLL3,SNAP25,FYN,ATP2B2,AHCYL1,LHFPL4,KIF1B,NPAS3,DCLK2,GPM6A,GPM6B,ACSL6,DDR1,DIRAS1,HAP1,GRIK2,GRIK3,MFSD2A,CELF3,ADGRG1,TUB,GDAP1L1,CELF5,SPATA6,ATCAY,CRMP1,NCAN,MAPK10,HES5,PROX1,DPYSL5,ELMO1,STMN4,SRGAP3,NTM,SNX27,DTNA,ARHGEF10L,ARHGAP12,ELAVL3,OLIG2" Coexpression Atlas BM Top 100 - ventral tegmental area BM Top 100 - ventral tegmental area Body Map 1.57E-21 6.98E-18 4.62E-20 4.15E-19 27 68 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,C1orf61,AQP4,SLC1A2,NSG2,SNAP25,GFAP,CNDP1,VXN,TF,SPX,INA,ANLN,OPALIN,PMP2,P2RY12,CALY,OLIG1,TMEM255A,SLC17A6,RFX4,OLIG2" Coexpression Atlas Arv_SC-LF_1000 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000 PCBC 4.31E-21 1.92E-17 1.26E-19 1.13E-18 101 988 "RIMKLA,CDHR1,TMEM74,SYNDIG1,MEG3,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,LRRTM4,SEMA6A,ACTL6B,C1orf61,PDZD4,SLC1A6,SLC8A2,DACH2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,SNCB,JPH4,SALL3,LHFPL4,DNER,SEPT3,ACSBG1,PCDH11X,SYT4,GNG3,GNG4,NODAL,UNC5D,KLHL4,GPM6A,GPM6B,GPR19,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,GRM3,PTPN5,MFSD2A,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,PRMT8,CA14,CHGA,PLEKHB1,CHRNB2,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,PACSIN1,ATCAY,BTBD17,POU3F4,ETNPPL,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,IGSF1,RIMS3,TUBB2B,JAKMIP2,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,FGFBP3,LINC00599,C2orf80,RASGRP2,SEZ6" Coexpression Atlas Arv_SC_fibroblast_2500_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 4.63E-21 2.06E-17 1.35E-19 1.21E-18 109 1120 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SEMA6A,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,JAKMIP3,SLC1A6,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,TMEM108,IGSF9B,SNCB,MEGF11,KIF21B,NMNAT2,JPH4,SALL3,LHFPL4,NAP1L2,SEPT3,RHBDL3,PCDH11X,GNG3,GNG4,UNC5D,KLHL4,GPM6B,GPR19,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,ADAMTS8,GRM3,PTPN5,TLL2,ZDHHC22,PAH,IGSF21,PADI2,C1orf94,CDH8,HRH3,CA14,CHGA,HPCA,NLGN3,DLGAP3,GDAP1L1,NRXN1,CAMKV,SEMA5B,SULT4A1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,POU3F4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,PRKCG,IGSF1,NOS1AP,RIMS3,DPYSL5,PLPPR5,TUBB2B,JAKMIP2,CADM2,PTPRD,KCNA6,PARD6A,PTPRZ1,KCNN3,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,RET,USH1C,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Arv_SC-H9hpx_2500_K5 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 6.23E-21 2.77E-17 1.80E-19 1.61E-18 101 993 "RIMKLA,CDHR1,TMEM74,ADGRV1,CSMD2,ADCY2,SLITRK1,GALNT13,RYR1,FABP7,NLGN4X,LRRTM4,SEMA6A,UNC79,HPCAL4,C1orf61,PDZD4,SH3GL2,PPM1E,BCAN,JAKMIP3,SLC1A6,SLC8A2,SHANK2,SCG3,CSPG5,SLCO1A2,DLL3,DDX25,B3GAT1,IGSF9B,SNCB,NMNAT2,JPH4,SALL3,LHFPL4,RCOR2,RND1,SEPT3,AJAP1,PCDH11X,GNG4,UNC5D,WWC1,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ADAMTS8,TLL2,ZDHHC22,PAH,IGSF21,PADI2,C1orf94,HRH3,CA14,CHGA,NLGN3,DLGAP3,GDAP1L1,CAMKV,SEMA5B,SULT4A1,CELF5,NECAB2,FAT3,ATCAY,BTBD17,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,DPYSL5,PLPPR5,TUBB2B,LRRTM3,JAKMIP2,CADM2,RABGAP1L,KCNQ2,NKAIN1,HS3ST4,SLC25A48,CALN1,FAM57B,DPP6,SLC25A18,RET,USH1C,FGFBP3,LINC00599,BSCL2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.31E-21 2.80E-17 1.81E-19 1.62E-18 53 313 "ASIC1,MEG3,CSMD2,RTN1,SLITRK1,FABP7,SCN3A,LINC00461,ASIC4,C1orf61,ANK3,LRRC4C,NSG2,ASCL1,SNAP25,MYT1L,JPH4,TTC9B,DNER,NCAM1,NELL1,GNG3,GPM6A,CACNA1E,VSTM2A,GRIA2,GRIA4,OPCML,PTPN5,INA,CDH8,TMEFF2,KIAA1549L,NRXN1,NRXN2,NEGR1,NXPH1,CRMP1,NCAN,PHACTR3,BRINP3,ANKS1B,CA10,PLPPR1,STMN4,OLIG1,DPP6,PAK5,SLC4A10,ELAVL3,ELAVL4,EN2,OLIG2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K4 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 7.40E-21 3.29E-17 2.11E-19 1.89E-18 47 247 "TTYH1,APC2,CEND1,MEG3,CHST15,LRRTM4,NTNG1,NLGN1,LRRC4C,TAGLN3,ASTN1,NRG3,CADM3,NPAS3,NCAM1,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,CACNA1A,GPM6B,TMEM151B,VSTM2A,PSD3,MFSD2A,PCDH9,CDH8,PDE1A,TUB,NLGN3,KIAA1549L,NRXN1,SEMA5B,NEGR1,FAT3,FEZ1,FMN2,MAPK10,BRINP3,TOX,STMN4,PTPRD,KCNN3,DTNA,EFNA3,LRRC23" Coexpression Atlas PCBC_ratio_EB blastocyst_vs_EB bone marrow_cfr-2X-p05 EB blastocyst_vs_EB bone marrow-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.07E-21 4.03E-17 2.57E-19 2.30E-18 56 351 "TTYH1,ABAT,WLS,FABP7,TUBB4A,DRAXIN,SEMA6A,CNIH2,APBA2,CACHD1,SLIT1,ATP1A2,TNIK,ILDR2,DNER,GFRA1,RCOR2,RND1,SEPT3,CNTN2,ADGRL3,WSCD1,GPM6A,GPM6B,CECR2,INA,ARHGAP19,LGI1,ADGRG1,CA14,SEMA5B,CPT1C,FAM181B,COL9A2,PRRX1,ATCAY,POU3F2,CRMP1,FEZ1,FAM131B,RIMS3,DPYSL5,TUBB2B,LRP8,RGMA,PTPRZ1,PANTR1,KCNQ2,NKAIN1,BEND5,L1CAM,RFX4,VANGL2,CACNG7,FGFBP3,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 9.57E-21 4.25E-17 2.69E-19 2.42E-18 41 187 "MAP6,RTN1,SCN3A,ANK2,ANK3,GPR153,SCG3,TAGLN3,DLL3,KIF21B,NMNAT2,DNER,NFASC,NCAM1,CLASP2,ARHGEF7,NHLH1,SYT4,GNG3,CNTN2,ZEB1,INA,CELF3,RBFOX2,FNDC5,GDAP1L1,NECAB2,ATCAY,POU3F2,CRMP1,CTNND2,MAPK8,RIMS3,STMN4,SLC17A6,FAM57B,RALGDS,L1CAM,ELAVL3,ELAVL4,EPB41" Coexpression Atlas BM Top 100 - hippocampus BM Top 100 - hippocampus Body Map 1.09E-20 4.84E-17 3.05E-19 2.73E-18 28 79 "ERMN,MOBP,FOXG1,MOG,PPM1E,SLC1A2,SPHKAP,SCN3B,CPLX2,C11orf87,NCDN,GPM6A,CACNA1E,NRGN,CAMK2A,VXN,GRIA1,GRIA2,OPCML,FBXL16,PCDH8,PDE1A,HPCA,CELF5,PLPPR4,KCNQ2,OLIG1,C2orf80" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.45E-20 6.43E-17 4.02E-19 3.61E-18 27 73 "TTYH1,NDRG2,FABP7,LINC00461,C1orf61,BCAN,SLC1A2,MT3,SCG3,ATP1A2,DNER,NFIA,LUZP2,GPM6B,ZEB1,ADGRG1,SCRG1,SERPINE2,PMP2,NCAN,SDC3,HES5,PTPRZ1,NTM,OLIG1,FGFBP3,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.64E-20 1.17E-16 7.28E-19 6.54E-18 43 212 "TTYH1,MBP,MEG3,ADGRV1,NDRG2,RTN1,SLITRK1,FABP7,LINC00461,FOXG1,ANK2,SHTN1,ASCL1,SNAP25,ATP2B2,SOX5,GAD2,LHFPL4,NPAS3,SEPT3,NFIA,PCDH11X,GPM6A,GPM6B,DIRAS1,HAP1,GRIK2,MFSD2A,CELF3,ADGRG1,TUB,CELF5,ATCAY,POU3F4,NCAN,MAPK10,HES5,DPYSL5,STMN4,SRGAP3,DTNA,ELAVL3,OLIG2" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4 facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4 Gudmap RNAseq 2.87E-20 1.27E-16 7.86E-19 7.06E-18 122 1371 "DPF1,TTYH1,ZFYVE27,MAP6,RIMKLA,SYT9,RTN3,CEND1,MEG3,ADGRV1,ARID1A,RTKN,CLIP1,RTN1,WAC,FABP7,SORCS1,TUBB4A,FHL1,SOX6,FOXM1,AMPH,ASRGL1,CDC42BPA,ANK2,USP28,PPM1E,APC,ST3GAL3,ST8SIA1,ZNF365,RUFY2,PKNOX2,YPEL4,CCDC88A,CADPS,SLIT1,TAGLN3,CAPRIN2,ASTN1,SNAP25,ATM,NRG3,PHYHIPL,MEGF11,SCN3B,SOX5,KIF21B,CADM3,KIF1B,NASP,INKA2,RCOR2,SEPT3,ARHGEF7,DCLK2,CAMTA1,GNG3,MYRF,PSRC1,CACNA1A,WSCD1,GPM6A,GPM6B,CACNB2,TCF7L2,ZEB1,GPR19,TCF12,HAP1,AZIN2,PTBP2,CAMK2A,BRSK2,PSD3,GRIK2,SHISA7,USP2,MFSD2A,CELF3,CDK11B,DCLK1,MAGI1,PDE1C,PRMT8,ADGRG1,JAM2,NLGN3,CADM1,KIAA1549L,NRXN1,SEMA5B,SLC25A27,SPATA6,NSD2,FAT3,CRMP1,NKAIN4,KCNT2,FEZ1,DOCK7,PROX1,TUBB2B,PTCH1,LRP8,SHD,PTPRZ1,SRGAP3,ARNT2,NKAIN1,KIF2A,DTNA,L1CAM,RFX5,PHC2,VANGL2,RBM12,ARHGAP12,ELAVL4,ROM1,PLEKHO1,EPB41" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K1 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 2.94E-20 1.30E-16 8.00E-19 7.18E-18 47 255 "APC2,CHST15,LRRTM4,FOXG1,NTNG1,NLGN1,LRRC4C,MADD,SORCS3,ASTN1,SNAP25,NRG3,NPAS3,GFRA1,SEPT3,NFIA,RHBDL3,SEMA4A,CACNA1A,CACNB2,HAP1,AZIN2,PSD3,GRIK2,MFSD2A,PAX6,PCDH9,PRMT8,GDAP1L1,KIAA1549L,NRXN1,NRXN2,NEGR1,FLRT1,CCDC136,CELF5,ATCAY,FEZ1,ATRNL1,FMN2,IGSF1,TOX,SV2A,SRGAP3,ARNT2,L1CAM,CACNG7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 4.35E-20 1.93E-16 1.18E-18 1.06E-17 33 121 "TTYH1,MBP,ADGRV1,RTN1,SLITRK1,FABP7,LINC00461,FOXG1,SHTN1,ASCL1,SNAP25,ATP2B2,GAD2,LHFPL4,GPM6A,GPM6B,DIRAS1,HAP1,GRIK2,MFSD2A,CELF3,ADGRG1,NRXN2,ATCAY,POU3F4,NCAN,MAPK10,HES5,DPYSL5,STMN4,DTNA,ELAVL3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.84E-20 3.48E-16 2.11E-18 1.90E-17 23 52 "MEG3,RTN1,FABP7,SCN3A,C1orf61,NSG2,ASCL1,SNAP25,MYT1L,DNER,NCAM1,GNG3,GPM6A,GRIA2,GRIA4,INA,NRXN1,NRXN2,CRMP1,STMN4,DPP6,ELAVL4,EN2" Coexpression Atlas BM Top 100 - substantia nigra BM Top 100 - substantia nigra Body Map 7.92E-20 3.52E-16 2.12E-18 1.90E-17 25 64 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,C1orf61,AQP4,SLC1A2,MYBPC1,GFAP,NKX2-2,CNDP1,VXN,TF,SPX,ANLN,OPALIN,PMP2,P2RY12,ETNPPL,OLIG1,TMEM255A,SLC17A6,OLIG2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.30E-19 5.77E-16 3.46E-18 3.10E-17 97 970 "TTYH1,EPS8,APC2,EMID1,CEND1,ACTN2,MEG3,IL17D,NDRG2,ADCY2,CHST15,LRRTM4,SEMA6C,SH3GL2,DOCK10,NTNG1,CCDC80,NLGN1,LRRC4C,SLC1A2,MSR1,SLC6A9,PDE8B,TAGLN3,DLL3,ASTN1,NRG3,CADM3,SOX10,JPH4,ARPP21,ADGRB2,NPAS3,NCAM1,NELL1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,GNG4,UNC5D,ADGRL3,TBX15,CACNA1A,GPM6B,NRGN,CECR2,TMEM151B,VSTM2A,PSD3,GRIK4,MFSD2A,REPS2,PCDH9,CDH8,PDE1A,TUB,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,COL9A2,PRRX1,FAT3,NXPH1,SNCAIP,NKAIN4,FEZ1,FMN2,MAPK10,BRINP3,TOX,PMEPA1,CADM2,LRP8,STMN4,CDH20,PTPRD,CCDC3,KCNK1,PCDH15,KCNN3,DLG2,RAP1GAP,BEND5,DTNA,ABCC9,EFNA3,VWA5A,EPB41L1,LRRC23,BAALC" Coexpression Atlas BM Top 100 - spinal cord BM Top 100 - spinal cord Body Map 1.93E-19 8.59E-16 5.11E-18 4.59E-17 25 66 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,AQP4,GFAP,NKX2-2,VXN,TF,OLR1,SPX,DCLK1,ANLN,CNTN1,PMP2,P2RY12,KLK6,OLIG1,TMEM255A,CALN1,SLC17A6,RFX4,OLIG2" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 2.02E-19 8.98E-16 5.32E-18 4.77E-17 43 223 "TTYH1,APC2,MEG3,RTN1,CHST15,LRRTM4,FOXG1,NTNG1,NLGN1,MSR1,ASCL1,TAGLN3,ASTN1,NRG3,NPAS3,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,VSTM2A,PSD3,GRIK2,MFSD2A,PCDH9,CDH8,PDE1A,NLGN3,KIAA1549L,NRXN1,SEMA5B,NEGR1,FAT3,FEZ1,FMN2,MAPK10,BRINP3,TOX,LRP8,STMN4,PTPRD,KCNN3,DTNA" Coexpression Atlas BM Top 100 - amygdala BM Top 100 - amygdala Body Map 2.27E-19 1.01E-15 5.94E-18 5.33E-17 26 73 "HPCAL4,FOXG1,SLC1A2,SNAP25,SCN3B,ARPP21,GPM6A,CACNA1E,NRGN,VSTM2A,GRIA1,GRIA2,OPCML,PTPN5,FBXL16,PCDH8,PDE1A,CELF5,PACSIN1,NCAN,PLPPR4,AK5,KCNJ4,KCNQ2,SLC17A6,C2orf80" Coexpression Atlas BM Top 100 - nodose nucleus BM Top 100 - nodose nucleus Body Map 2.98E-19 1.32E-15 7.74E-18 6.95E-17 25 67 "MAG,MBP,PAQR6,ERMN,AMER2,MOBP,MOG,BCAS1,GFAP,NKX2-2,MYRF,CNTN2,CNDP1,VXN,GRM3,TF,HAPLN2,ANLN,PMP2,P2RY12,CMTM5,KLK6,ANKS1B,OLIG1,OLIG2" Coexpression Atlas BM Top 100 - hypothalamus BM Top 100 - hypothalamus Body Map 3.38E-19 1.50E-15 8.74E-18 7.84E-17 26 74 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,AQP4,NSG2,GFAP,NKX2-2,GNAS,CNDP1,TF,SPX,INA,SEZ6L,ANLN,OPALIN,CELF5,P2RY12,CALY,RIMS3,OLIG1,SLC17A6,C2orf80,OLIG2" Coexpression Atlas ratio_SC_vs_MESO_2500_K3 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 3.43E-19 1.53E-15 8.82E-18 7.92E-17 84 776 "TTYH1,RIMKLA,CSMD2,ADCYAP1R1,RYR1,FABP7,TUBB4A,NLGN4X,DRAXIN,SEMA6A,ACTL6B,HPCAL4,CNIH2,PPM1E,BCAN,NLGN1,LRRC55,SHANK2,SCG3,CSPG5,DDX25,IGSF9B,SNCB,NMNAT2,JPH4,SALL3,LHFPL4,NAP1L2,RND1,RHBDL3,PCDH11X,GNG3,GNG4,WWC1,CACNA1A,WSCD1,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRM3,FBXL16,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,DCLK1,HRH3,CHGA,CHRNB2,GDAP1L1,NRXN1,CAMKV,CELF5,ATCAY,BTBD17,POU3F4,CRMP1,ATRNL1,RIMS4,IGSF1,FAM131B,ECE2,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRZ1,RABGAP1L,KCNN3,KCNQ2,NKAIN1,FAM57B,PAK5,ST8SIA3,RGS7,CACNG7,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas Arv_SC-hpx_blastocyst_1000_K3 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 3.71E-19 1.65E-15 9.48E-18 8.51E-17 66 512 "RIMKLA,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,SEMA6A,C1orf61,PDZD4,SH3GL2,JAKMIP3,SLC1A6,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,SALL3,LHFPL4,RCOR2,SEPT3,PCDH11X,GNG4,UNC5D,KLHL4,GPM6B,HAP1,CECR2,SYT6,GRIA4,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,SULT4A1,CELF5,NECAB2,FAT3,BTBD17,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,TUBB2B,LRRTM3,CADM2,KCNQ2,NKAIN1,HS3ST4,DPP6,RET,USH1C,LINC00599,SEZ6" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000 FaceBase_RNAseq 5.87E-19 2.61E-15 1.49E-17 1.34E-16 96 975 "APC2,EMID1,LGR4,ACTN2,NDRG2,PLEKHG5,ADCY2,CHST15,TESK2,LRRTM4,MOBP,FOXG1,SGIP1,SH3GL2,DOCK10,NTNG1,CCDC80,NLGN1,LRRC4C,SLC1A2,MADD,SORCS3,ASTN1,SNAP25,TMEM151A,NRG3,ATP1A3,TNIK,GAD2,JPH4,ARPP21,ADGRB2,NPAS3,C11orf87,GFRA1,SEPT3,NFIA,RHBDL3,PCDH11X,C1QC,KAZN,SEMA4A,ADGRL3,CACNA1A,CACNB2,HAP1,AZIN2,PSD3,GRIK2,TMEM25,LEFTY2,MFSD2A,PAX6,REPS2,PCDH9,PDE1A,PRMT8,HPSE2,GDAP1L1,SERPINE2,KIAA1549L,NRXN1,NRXN2,NEGR1,FLRT1,CCDC136,CELF5,ATCAY,NXPH1,SNCAIP,FEZ1,ATRNL1,FMN2,IGSF1,MASP1,TOX,ZNF385B,PMEPA1,CADM2,LRP8,KCNA6,SV2A,SRGAP3,RABGAP1L,CCDC3,ARNT2,PCDH15,DLG2,RALGDS,RAP1GAP,L1CAM,CACNG7,VWA5A,ELAVL4,TMEM100,PRRT4" Coexpression Atlas Arv_SC-H9hpx_1000_K5 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 8.36E-19 3.71E-15 2.11E-17 1.89E-16 65 506 "RIMKLA,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,SEMA6A,C1orf61,PDZD4,SH3GL2,JAKMIP3,SLC1A6,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,SALL3,LHFPL4,RCOR2,SEPT3,PCDH11X,GNG4,UNC5D,GPM6B,HAP1,CECR2,SYT6,GRIA4,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,SULT4A1,CELF5,NECAB2,FAT3,BTBD17,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,TUBB2B,LRRTM3,CADM2,KCNQ2,NKAIN1,HS3ST4,DPP6,RET,USH1C,LINC00599,SEZ6" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000_K2 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 8.76E-19 3.89E-15 2.20E-17 1.97E-16 41 210 "APC2,MBP,ADGRV1,CHST15,LRRTM4,LINC00461,FHL1,FOXG1,NLGN1,SHTN1,ASCL1,ASTN1,NRG3,PHYHIPL,ILDR2,NPAS3,LMO3,SEMA4A,WSCD1,DIRAS1,HAP1,PSD3,MFSD2A,PAX6,PCDH9,ADGRG1,KIAA1549L,NRXN1,NEGR1,FLRT1,FEZ1,FMN2,HES5,TOX,DPYSL5,LRP8,DTNA,RFX4,ELAVL3,ELAVL4,EPB41" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.08E-18 4.81E-15 2.70E-17 2.43E-16 59 427 "MAPT,EYA1,CSMD3,RTN1,SLITRK1,FABP7,SORCS1,SCN3A,LRRTM4,KIAA1109,SGIP1,APC,NTNG1,ST8SIA1,SLC7A14,DACH2,CADPS,ASCL1,ASTN1,SNAP25,SCN3B,SOX5,AHCYL1,DNER,NAP1L2,NPAS3,C11orf87,CLASP2,GFRA1,NFIA,PCDH11X,SYT4,ADGRL3,GRIA1,GRIA2,INA,CDH10,DCLK1,RBFOX2,DUSP26,CADM1,CNTN1,PRRX1,FAT3,VCAN,DZIP3,NRSN1,MAPK10,DNAJC6,JAKMIP2,STMN4,PTPRO,KCNMA1,KCNQ2,CALN1,FAM13C,RET,ST8SIA3,ELAVL4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K1 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.15E-18 5.11E-15 2.86E-17 2.56E-16 43 233 "TTYH1,APC2,MEG3,CHST15,LRRTM4,SEMA6C,NLGN1,LRRC4C,TAGLN3,ASTN1,NRG3,NPAS3,NFIA,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,ACSL6,AZIN2,VSTM2A,PSD3,MFSD2A,PCDH9,CDH8,NLGN3,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,FAT3,FEZ1,FMN2,MAPK10,BRINP3,TOX,STMN4,PTPRD,SV2A,KCNN3,DTNA,LRRC23" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.39E-18 6.20E-15 3.44E-17 3.09E-16 95 971 "TTYH1,EPS8,PRR5L,APC2,EMID1,ACTN2,MEG3,IL17D,NDRG2,ADCY2,CHST15,LRRTM4,SEMA6C,SH3GL2,DOCK10,NTNG1,CCDC80,NLGN1,LRRC4C,SLC1A2,MSR1,SLC6A9,PDE8B,TAGLN3,ASTN1,NRG3,JPH4,ARPP21,TTLL9,ADGRB2,NPAS3,NELL1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,GNG4,UNC5D,ADGRL3,CACNA1A,GPM6B,ACSL6,NRGN,AZIN2,CAMK2A,VSTM2A,PSD3,GRIA1,GRIK4,MFSD2A,REPS2,PCDH9,CDH8,PDE1A,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,COL9A2,PRRX1,FAT3,NXPH1,NKAIN4,FEZ1,FMN2,MAPK10,MASP1,BRINP3,TOX,ZNF385B,PMEPA1,CADM2,LRP8,STMN4,PTPRD,SV2A,CCDC3,KCNK1,PCDH15,KCNN3,DLG2,RAP1GAP,BEND5,DTNA,ABCC9,EFNA3,VWA5A,EPB41L1,LRRC23,BAALC" Coexpression Atlas PCBC_ECTO_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500 PCBC 1.53E-18 6.80E-15 3.76E-17 3.37E-16 64 498 "MAP6,TMEM74,ADGRV1,FABP7,SLC30A10,C1orf61,SESN3,SLC1A6,BCO1,PKNOX2,SCG3,SLCO1A2,DDX25,ASTN1,B3GAT1,PHYHIPL,SOX1,ILDR2,SALL3,LHFPL4,LMO3,COLGALT2,STOX1,SMOC1,NHLH1,UNC5D,PRUNE2,GPM6A,FAM69C,CAMK2A,GRM3,PTPN5,CELF3,KCNK10,PAX6,IGSF21,CDH8,LGI1,HAPLN2,CA14,CELF5,NECAB2,ATCAY,BTBD17,POU3F2,NKAIN4,KCNT2,NCAN,CTNND2,HES5,RIMS3,DPYSL5,ZNF385B,CADM2,STMN4,KCNA1,OLFM3,PTPRD,KCNQ2,TMEM255A,FAM57B,RFX4,RLBP1,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.72E-18 7.63E-15 4.19E-17 3.76E-16 33 135 "MAPT,RTN1,SLITRK1,ADCYAP1R1,FABP7,ANK2,SLC7A14,ASCL1,SCG3,SNAP25,ATP2B2,SCN3B,C11orf87,ARHGEF7,SYT4,BRSK2,CDC42,LGI1,PIRT,TUB,TMEFF2,DUSP26,CNTN1,CRMP1,PHACTR3,NRSN1,MAPK10,STMN4,PTPRO,KCNQ2,RET,ATL1,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.14E-18 9.51E-15 5.20E-17 4.67E-16 32 127 "MEG3,RTN1,FABP7,AMER2,SCN3A,LINC00461,ANK3,NSG2,TAGLN3,DKK3,SCN3B,MYT1L,KIF21B,NCAM1,LMO3,CLASP2,GFRA1,GPM6A,INA,ZDHHC22,PCSK2,ADGRG1,TUB,TMEFF2,NEGR1,SF1,KIAA0408,NTM,LINC00599,ELAVL4,EN2,RCAN2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 2.58E-18 1.15E-14 6.22E-17 5.58E-16 44 249 "TTYH1,APC2,MEG3,ADGRV1,RTN1,CHST15,LRRTM4,NTNG1,NLGN1,TAGLN3,ASTN1,NRG3,NPAS3,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,CACNA1A,GPM6B,TMEM151B,VSTM2A,PSD3,MFSD2A,PAX6,PCDH9,CDH8,KIAA1549L,NRXN1,SEMA5B,NEGR1,FAT3,POU3F4,FEZ1,FMN2,CTNND2,MAPK10,BRINP3,TOX,DPYSL5,SHD,STMN4,NTM,DTNA" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.14E-18 1.39E-14 7.54E-17 6.77E-16 24 66 "MEG3,RTN1,SCN3A,LINC00461,SCG3,TAGLN3,NCAM1,NEUROD1,SEPT3,NHLH1,CNTN2,GPM6A,ZEB1,TCF12,GRIA2,INA,FNDC5,ADGRG1,NCAN,PANTR1,ELAVL3,ELAVL4,EN2,EPB41" Coexpression Atlas BM Top 100 - cerebral cortex BM Top 100 - cerebral cortex Body Map 3.36E-18 1.49E-14 8.02E-17 7.20E-16 25 73 "ERMN,MOBP,FOXG1,MOG,SLC1A2,SNAP25,ATP2B2,SCN3B,ARPP21,NRGN,VXN,VSTM2A,GRIA2,OPCML,PTPN5,PDE1A,ANLN,CABP1,CELF5,RIMS3,KCNJ4,KCNQ2,OLIG1,ELAVL4,C2orf80" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.08E-18 1.82E-14 9.70E-17 8.71E-16 37 177 "TTYH1,APC2,ADGRV1,SLITRK1,FABP7,LINC00461,FOXG1,NSG2,ASCL1,TAGLN3,SNAP25,ATP2B2,NPAS3,ARHGEF7,PCDH11X,WSCD1,GPM6A,GPM6B,ACSL6,DIRAS1,HAP1,GRIK2,MFSD2A,CELF3,ADGRG1,ATCAY,POU3F4,CRMP1,NCAN,MAPK10,HES5,PROX1,DPYSL5,STMN4,SRGAP3,ELAVL3,OLIG2" Coexpression Atlas Arv_EB-LF_500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 7.70E-18 3.42E-14 1.82E-16 1.63E-15 44 256 "FABP7,LINC00461,ACTL6B,HPCAL4,C1orf61,NSG2,SLIT1,B3GAT1,TMEM151A,PHYHIPL,GAD2,DNER,NELL1,SYT4,MYRF,CNTN2,GPM6A,GRIA2,GRIA4,TF,OLR1,CELF3,PAX6,PCDH8,LGI1,SCRG1,HPSE2,GDAP1L1,CELF5,POU3F2,NKAIN4,ATRNL1,NCAN,DPYSL5,STMN4,PTPRO,KCNQ2,SLC17A6,DPP6,RFX4,ELAVL3,ELAVL4,C2orf80,EN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.77E-18 4.34E-14 2.30E-16 2.06E-15 29 107 "MAPT,RTN1,SLITRK1,FABP7,ANK2,SLC7A14,ASCL1,ASPH,SNAP25,SCN3B,DNER,C11orf87,ARHGEF7,SYT4,BRSK2,LGI1,PIRT,TMEFF2,DUSP26,CNTN1,CRMP1,NRSN1,MAPK10,DNAJC6,STMN4,KCNQ2,RET,ST8SIA3,ELAVL4" Coexpression Atlas BM Top 100 - vestibular nuclei superior BM Top 100 - vestibular nuclei superior Body Map 1.05E-17 4.64E-14 2.44E-16 2.19E-15 24 69 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,AQP4,SNAP25,GFAP,VAMP1,GNAS,CNDP1,TF,SPX,INA,ANLN,PMP2,P2RY12,OLIG1,TMEM255A,SLC17A6,ELAVL4,C2orf80,OLIG2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.12E-17 4.96E-14 2.60E-16 2.33E-15 39 203 "EYA1,FABP7,SORCS1,SCN3A,DISP3,SGIP1,ANK2,CADPS,SCG3,SNAP25,PHYHIPL,SCN3B,TNIK,NAP1L2,SYT4,DCLK2,GRIA2,GRIA4,GRIK2,INA,PCDH9,CDH10,LGI1,CADM1,NRXN1,CNTN1,KCNT2,PHACTR3,KIAA0408,JAKMIP2,PTPRZ1,SRGAP3,DLG2,SLC6A15,ST8SIA3,RGS7,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_500 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.20E-17 5.32E-14 2.77E-16 2.49E-15 31 125 "EYA1,CSMD3,RTN1,FABP7,SCN3A,ANK2,SLC7A14,NSG2,CADPS,SCG3,SNAP25,SCN3B,NCAM1,GFRA1,SEPT3,GRIA2,INA,DCLK1,SERPINE2,CADM1,NRXN1,CRMP1,FEZ1,NRSN1,MAPK10,TUBB2B,STMN4,DLG2,L1CAM,RET,ELAVL4" Coexpression Atlas ratio_SC_vs_MESO_500_K5 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 1.52E-17 6.77E-14 3.51E-16 3.15E-15 47 296 "RIMKLA,RYR1,FABP7,PPM1E,BCAN,NLGN1,SCG3,SNCB,NMNAT2,LHFPL4,NAP1L2,RHBDL3,GNG3,GNG4,ACSL6,TMEM151B,SYT6,GRIA4,GRM3,FBXL16,TLL2,ZDHHC22,PAH,C1orf94,DCLK1,HRH3,CHGA,GDAP1L1,NRXN1,CAMKV,ATCAY,BTBD17,RIMS4,IGSF1,FAM131B,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRZ1,RABGAP1L,FAM57B,RGS7,CACNG7,FGFBP3,LINC00599" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.12E-17 9.43E-14 4.84E-16 4.34E-15 38 196 "ABAT,MEG3,ADGRV1,LINC00461,SFPQ,CADPS,ASCL1,TAGLN3,DLL3,GFRA1,RCOR2,NELL1,NEUROD1,SEPT3,RHBDL3,NHLH1,PSRC1,TCF12,PTBP2,VXN,BRSK2,PSD3,CRB1,CELF3,PCDH8,PCSK2,FNDC5,SEMA5B,BTBD17,POU3F2,PROX1,CEP170,PANTR1,KCNQ2,ELAVL4,EN2,PLEKHO1,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.12E-17 9.43E-14 4.84E-16 4.34E-15 38 196 "ABAT,MEG3,ADGRV1,LINC00461,SFPQ,CADPS,ASCL1,TAGLN3,DLL3,GFRA1,RCOR2,NELL1,NEUROD1,SEPT3,RHBDL3,NHLH1,PSRC1,TCF12,PTBP2,VXN,BRSK2,PSD3,CRB1,CELF3,PCDH8,PCSK2,FNDC5,SEMA5B,BTBD17,POU3F2,PROX1,CEP170,PANTR1,KCNQ2,ELAVL4,EN2,PLEKHO1,EPB41" Coexpression Atlas ratio_SC_vs_DE_500_K5 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 2.21E-17 9.83E-14 5.02E-16 4.50E-15 44 263 "TTYH1,CEND1,RYR1,ACTL6B,HPCAL4,SLITRK3,BCAN,LRRC55,KIF21B,JPH4,RND1,SEPT3,RHBDL3,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRIN1,TLL2,ZDHHC22,PAH,HRH3,CHGA,CHRNB2,NLGN3,NRXN2,CAMKV,BTBD17,POU3F4,RIMS4,RAB39A,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,NTM,KCNN3,ATL1,CACNG7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.91E-17 1.29E-13 6.57E-16 5.89E-15 29 111 "DPF1,APC2,MBP,RTN1,LINC00461,NSG2,ASCL1,SNAP25,ATP1A3,GAD2,LHFPL4,NPAS3,ACSBG1,DCLK2,GPM6A,GPM6B,DDR1,GRIK3,MFSD2A,CELF3,GDAP1L1,POU3F4,CRMP1,NCAN,HES5,PROX1,ELMO1,STMN4,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE76381_iPSMoleculeCountsPMLog2 3.42E-17 1.52E-13 7.67E-16 6.88E-15 33 148 "RTN1,SLITRK1,ACTL6B,ANK3,APC,NSG2,ASTN1,B3GAT1,FYN,SCN3B,JPH4,NCAM1,LMO3,GFRA1,SEPT3,ARHGEF7,GNG4,GPM6B,INA,CELF3,KCNK10,CHGA,NEGR1,CELF5,FAT3,TENM4,JAKMIP2,CADM2,SLC17A6,PLEKHB2,BSDC1,RET,ELAVL3" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500 FaceBase_ST1 4.77E-17 2.12E-13 1.07E-15 9.57E-15 50 342 "TTYH1,MAP6,CEND1,MEG3,NDRG2,KLHL32,FABP7,LINC00461,C1QTNF4,FOXG1,MT3,ASCL1,CGREF1,SCG3,CSPG5,TAGLN3,GAD2,NKX6-2,TTC9B,NPAS3,FGF17,NFIA,NRGN,USP2,MFSD2A,CELF3,KCNK10,TPD52,CHGA,JAM2,GDAP1L1,FAM181B,ATCAY,BTBD17,POU3F4,NKAIN4,FEZ1,NRSN1,HES5,TUBB2B,PMEPA1,SHD,STMN4,SRGAP3,OLIG1,RGS10,LMO1,FGFBP3,ELAVL3,OLIG2" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500 FaceBase_RNAseq 7.65E-17 3.40E-13 1.70E-15 1.53E-14 61 495 "TTYH1,APC2,CEND1,ADGRV1,ERMN,TUBB4A,FHL1,NTNG1,CCDC80,SHTN1,NSG2,DLL3,TMEM108,PHYHIPL,ATP2B2,SOX5,ILDR2,SALL3,TTLL9,LMO3,C11orf87,SEPT3,AJAP1,ROBO3,GNG3,WWC1,TCF7L2,DIRAS1,HAP1,CECR2,RFFL,GRIK2,INA,CELF3,CDK11B,PAX6,PRMT8,TUB,KIAA1549L,NRXN2,NXPH1,POU3F4,NKAIN4,NCAN,CTNND2,HES5,MASP1,ZBTB16,DPYSL5,CA10,JAKMIP2,SHD,CDH20,PTPRZ1,KCNK1,DTNA,ST8SIA3,RFX4,ELAVL3,OLIG2,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.82E-17 3.48E-13 1.73E-15 1.55E-14 52 372 "EYA1,CSMD3,NDRG2,RTN1,FABP7,TUBB4A,SCN3A,LRRC7,ANK2,SLC7A14,NSG2,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,NCAM1,GFRA1,SEPT3,C1QC,ASTN2,GNG3,CACNA1E,DDR2,GRIA2,INA,CELF3,TNR,DCLK1,HPSE2,TMEFF2,SERPINE2,CADM1,NRXN1,PRRX1,FAT3,CRMP1,NKAIN4,FEZ1,VCAN,NRSN1,MAPK10,MASP1,TUBB2B,STMN4,DLG2,TMEM255A,L1CAM,ABCC9,RET,ATL1,ELAVL4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.06E-16 4.72E-13 2.34E-15 2.10E-14 29 116 "MAP6,CEND1,RTN1,ADCYAP1R1,UNC79,APBA2,APBB1,SLC7A14,NSG2,TAGLN3,DDX25,TTC9B,NFASC,NCAM1,GFRA1,SEPT3,INA,DCLK1,GDAP1L1,SERPINE2,CRMP1,FEZ1,NRSN1,PROX1,DPYSL5,TUBB2B,STMN4,L1CAM,RET" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE76381_ESMoleculeCountsPMLog2 1.28E-16 5.67E-13 2.79E-15 2.51E-14 31 135 "MAP6,RTN1,SCN3A,ANK3,NSG2,SCG3,TAGLN3,DLL3,B3GAT1,DNER,NFASC,NCAM1,GFRA1,NEUROD1,NHLH1,SYT4,GNG3,CNTN2,GPM6A,ZEB1,INA,FNDC5,ADGRG1,POU3F2,STMN4,SLC17A6,RALGDS,L1CAM,RGS10,ELAVL3,EPB41" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.36E-16 6.03E-13 2.96E-15 2.65E-14 91 973 "APC2,EMID1,MBP,LGR4,ACTN2,ADGRV1,EYA1,IL17D,NDRG2,ADCY2,ERMN,CHST15,LRRTM4,LINC00461,FHL1,FOXG1,DOCK10,NTNG1,CCDC80,NLGN1,SHTN1,SLC1A2,ASCL1,DLL3,ASTN1,NRG3,PHYHIPL,ILDR2,GAD2,NMNAT2,JPH4,STARD10,ADGRB2,NPAS3,LMO3,SMOC1,FGF17,NFIA,PCDH11X,C1QC,SEMA4A,ADGRL3,WWC1,WSCD1,DIRAS1,HAP1,CECR2,PSD3,MFSD2A,PAX6,REPS2,PCDH9,TPD52,PDE1A,ADGRG1,CA14,CADM1,KIAA1549L,NRXN1,NEGR1,TJP2,FLRT1,NECAB2,NXPH1,FEZ1,OSBPL3,PLCH2,FMN2,HES5,ZBTB16,TOX,DPYSL5,PSMD13,PMEPA1,CADM2,LRP8,RABGAP1L,CCDC3,KCNK1,PCDH15,NAV2,DLG2,DLG3,SUSD4,DTNA,RFX4,VWA5A,RAVER2,ELAVL3,ELAVL4,EPB41" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.46E-16 6.48E-13 3.16E-15 2.84E-14 27 100 "TTYH1,ADGRV1,SLITRK1,FABP7,LINC00461,FOXG1,SOX6,ASCL1,SCG3,PHYHIPL,ILDR2,ACSBG1,GNG3,GPM6A,HAP1,CECR2,INA,PAX6,ADGRG1,JAM2,SEMA5B,CTNND2,HES5,JAKMIP2,PTPRZ1,ELAVL3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-16 9.69E-13 4.70E-15 4.22E-14 22 63 "MEG3,RTN1,FABP7,SCN3A,C1orf61,ANK3,NSG2,ASCL1,MYT1L,DNER,NCAM1,GPM6A,GRIA2,GRIA4,INA,NRXN1,NRXN2,NEGR1,CRMP1,ELAVL3,ELAVL4,EN2" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 2.19E-16 9.72E-13 4.70E-15 4.22E-14 40 232 "APC2,MEG3,ADGRV1,CHST15,LRRTM4,NTNG1,NLGN1,MSR1,TAGLN3,ASTN1,NRG3,NPAS3,RHBDL3,ASTN2,SEMA4A,CACNA1A,GPM6B,VSTM2A,PSD3,GRIK2,MFSD2A,PAX6,PCDH9,CDH8,PDE1A,NLGN3,KIAA1549L,NRXN1,SEMA5B,NEGR1,FAT3,FEZ1,FMN2,MAPK10,BRINP3,TOX,LRP8,STMN4,KCNN3,DTNA" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 2.27E-16 1.01E-12 4.86E-15 4.36E-14 50 355 "MAP6,RTN1,SCN3A,ANK2,ANK3,RUFY2,GPR153,SCG3,TAGLN3,DLL3,KIF21B,NMNAT2,DNER,NFASC,NCAM1,CLASP2,GFRA1,ARHGEF7,NHLH1,OS9,SYT4,GNG3,CNTN2,ZEB1,INA,CELF3,RBFOX2,FNDC5,ACOT7,GDAP1L1,SULT4A1,NECAB2,ATCAY,POU3F2,CRMP1,CTNND2,MAPK8,RIMS3,PSMD13,STMN4,AK5,SLC17A6,FAM57B,RALGDS,L1CAM,RGS10,ELAVL3,ELAVL4,BSCL2,EPB41" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-OSK-L-l-p53KD_cfr-2X-p05 Mesoderm Day 30-reprogram_NA_vs_Mesoderm Day 30-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.36E-16 1.05E-12 5.00E-15 4.49E-14 38 210 "TTYH1,SERPINA3,MAPT,RTN1,FABP7,NSG2,SLIT1,ATP1A3,KIF21B,DNER,NCAM1,GJB1,SEPT3,ROBO3,GNG4,ANO4,GPM6A,NPPA,INA,CELF3,SERPINE2,SEMA5B,ATCAY,CRMP1,FEZ1,HES5,DPYSL5,ITIH2,STMN4,PTPRZ1,CCDC3,PANTR1,NKAIN1,RAP1GAP,L1CAM,USH1C,CACNG7,ELAVL3" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-episomal_cfr-2X-p05 Mesoderm Day 30-method_NA_vs_Mesoderm Day 30-method_episomal-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.36E-16 1.05E-12 5.00E-15 4.49E-14 38 210 "TTYH1,SERPINA3,MAPT,RTN1,FABP7,NSG2,SLIT1,ATP1A3,KIF21B,DNER,NCAM1,GJB1,SEPT3,ROBO3,GNG4,ANO4,GPM6A,NPPA,INA,CELF3,SERPINE2,SEMA5B,ATCAY,CRMP1,FEZ1,HES5,DPYSL5,ITIH2,STMN4,PTPRZ1,CCDC3,PANTR1,NKAIN1,RAP1GAP,L1CAM,USH1C,CACNG7,ELAVL3" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.31E-16 1.47E-12 6.97E-15 6.25E-14 27 103 "APC2,CHST15,LRRTM4,NTNG1,NLGN1,ASTN1,NRG3,NPAS3,NFIA,RHBDL3,PCDH11X,SEMA4A,VSTM2A,PSD3,MFSD2A,PCDH9,CDH8,PDE1A,KIAA1549L,NRXN1,SEMA5B,NEGR1,FEZ1,FMN2,BRINP3,TOX,DTNA" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000 FaceBase_RNAseq 3.99E-16 1.77E-12 8.36E-15 7.50E-14 90 973 "TTYH1,EPS8,RPL38,APC2,EMID1,ACTN2,MEG3,ADGRV1,IL17D,NDRG2,RTN1,ADCY2,TUBB4A,CHST15,LRRTM4,SEMA6A,DOCK10,NTNG1,CCDC80,NLGN1,SLC1A2,MSR1,SLC6A9,TAGLN3,ASTN1,NRG3,DKK3,JPH4,ARPP21,ADGRB2,NPAS3,NELL1,ACSBG1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,UNC5D,ADGRL3,CACNA1A,WSCD1,GPM6B,TMEM151B,VSTM2A,PSD3,MFSD2A,PAX6,REPS2,PCDH9,CDH8,PDE1A,HPSE2,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,COL9A2,FAT3,NXPH1,POU3F4,SNCAIP,NKAIN4,FEZ1,FMN2,CTNND2,MAPK10,BRINP3,TOX,DPYSL5,PMEPA1,CADM2,LRP8,SHD,STMN4,NTM,CCDC3,PCDH15,DLG2,BEND5,DTNA,ABCC9,RGS10,PIANP,VWA5A,EPB41L1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.10E-16 1.82E-12 8.55E-15 7.68E-14 49 347 "TTYH1,MEG3,ADGRV1,FABP7,C1orf61,SFPQ,LRRC4C,ASCL1,SOX1,ILDR2,NMNAT2,NKX6-2,SALL3,NASP,RND1,ARHGEF7,NKX2-2,WWC1,ZEB1,TCF12,NUDT21,VXN,GRM3,PCDH8,SEZ6L,LINC01102,HMGB1,SCRG1,JAM2,NRXN1,FAT3,BTBD17,POU3F2,SF1,TENM4,NCAN,CTNND2,HES5,TOX,PTCH1,PMEPA1,RGMA,C1orf109,PTPRZ1,PANTR1,RALGDS,RFX4,FGFBP3,EN2" Coexpression Atlas BM Top 100 - midbrain BM Top 100 - midbrain Body Map 4.33E-16 1.93E-12 9.00E-15 8.08E-14 23 72 "MAG,MBP,PAQR6,ERMN,FGF1,MOBP,MOG,CADPS,SNAP25,GFAP,CNDP1,VXN,TF,SPX,INA,ANLN,P2RY12,KLK6,OLIG1,CALN1,SLC17A6,ELAVL4,OLIG2" Coexpression Atlas BM Top 100 - medulla BM Top 100 - medulla Body Map 4.69E-16 2.08E-12 9.69E-15 8.70E-14 22 65 "MAG,MBP,PAQR6,ERMN,MOBP,MOG,AQP4,GFAP,NKX2-2,CNDP1,VXN,TF,DCLK1,ANLN,CNTN1,PMP2,P2RY12,OLIG1,TMEM255A,SLC17A6,RFX4,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.57E-16 2.92E-12 1.35E-14 1.21E-13 90 981 "EPS8,ACTN2,ADGRV1,ARID1A,WAC,ERMN,HPCAL4,MOBP,FOXG1,SEMA6C,SH3GL2,DOCK10,GAS7,SLC1A2,BCO1,MSR1,SLC6A9,CCDC88A,PDE8B,SCG3,SLCO1A2,DLL3,ADGRA1,ATP1A3,ATP2B2,TNIK,ARPP21,TTLL9,NASP,C11orf87,ACSBG1,NFIA,ZNF638,GNG4,GOLGB1,TMEM136,CACNA1A,ACSL6,CLEC9A,PTBP2,CAMK2A,GRIA1,GRIK2,OPCML,TMEM25,LEFTY2,INA,CELF3,CDK11B,REPS2,PDE4B,HPSE2,TUB,NLGN3,GDAP1L1,SERPINE2,KIAA1549L,NRXN2,COL9A2,FAT3,ATCAY,NXPH1,NKAIN4,MICAL2,PLCH2,IGSF1,MAPK10,HES5,MASP1,ZBTB16,ZNF385B,ITGAV,JAKMIP2,PMEPA1,CADM2,LRP8,STMN4,KCNA6,PCDH15,DLG2,CAB39L,RAB3IL1,PID1,ABCC9,ST8SIA3,LPAR6,ELAVL3,PRRT4,RASGRP2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.96E-16 4.43E-12 2.04E-14 1.83E-13 21 60 "TTYH1,NDRG2,ADCYAP1R1,FABP7,LINC00461,C1orf61,BCAN,ATP1A2,SMOC1,NFIA,WWC1,GPM6B,SEZ6L,SCRG1,SERPINE2,PMP2,NCAN,HES5,PTPRZ1,PANTR1,FGFBP3" Coexpression Atlas Arv_SC-HD_1000 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000 PCBC 1.08E-15 4.78E-12 2.18E-14 1.96E-13 90 989 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,JPH4,SALL3,LHFPL4,SEPT3,ACSBG1,ABCC8,PCDH11X,C1QC,GNG3,GNG4,UNC5D,KLHL4,GPM6A,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CA14,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,RIMS4,RAB39A,IGSF1,RIMS3,DPYSL5,TUBB2B,ZNF385B,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,RET,USH1C,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Arv_SC_fibroblast_1000 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 1.08E-15 4.78E-12 2.18E-14 1.96E-13 90 989 "RIMKLA,TMEM74,ADGRV1,CSMD2,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SCN4B,SEMA6A,C1orf61,PDZD4,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,JPH4,SALL3,LHFPL4,SEPT3,ACSBG1,ABCC8,PCDH11X,C1QC,GNG3,GNG4,UNC5D,KLHL4,GPM6A,GPM6B,HAP1,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,GRIN1,GRM3,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CA14,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,RIMS4,RAB39A,IGSF1,RIMS3,DPYSL5,TUBB2B,ZNF385B,CADM2,PTPRZ1,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,DPP6,RET,USH1C,RGS7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.12E-15 4.95E-12 2.25E-14 2.02E-13 26 99 "ADGRV1,SLITRK1,FABP7,LINC00461,FOXG1,ASCL1,SCG3,ATP1A3,ILDR2,GAD2,ACSBG1,ROBO3,GPM6A,GPM6B,HAP1,INA,CELF3,ADGRG1,ATCAY,POU3F4,NCAN,HES5,DPYSL5,STMN4,ELAVL3,OLIG2" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K1 facebase_RNAseq_e10.5_Emin_MedNas_2500_K1 Gudmap RNAseq 1.19E-15 5.29E-12 2.39E-14 2.15E-13 94 1060 "DPF1,RIMKLA,SYT9,CEND1,ARID1A,CLIP1,RTN1,WAC,SORCS1,TUBB4A,LRRTM4,FHL1,ELMOD1,SOX6,SELL,SFPQ,ANK2,USP28,PPM1E,APC,NLGN1,ST8SIA1,MADD,PKNOX2,ARHGAP5,CCDC88A,DACH2,CADPS,CSPG5,TAGLN3,CAPRIN2,ASTN1,SMARCE1,ATM,NRG3,PHYHIPL,SCN3B,SOX5,CADM3,ADGRB2,NASP,RCOR2,SEPT3,ARHGEF7,CAMTA1,GNG3,CACNA1A,GPM6A,GPM6B,ZEB1,GPR19,TCF12,PTBP2,BRSK2,SHISA7,USP2,MFSD2A,CDK11B,PDE3B,PRMT8,ADGRG1,HPCA,KIAA1549L,NRXN1,SEMA5B,PIK3CD,FAM181B,SPATA6,NSD2,FAT3,CRMP1,CSF3R,DOCK7,CTNND2,MAPK8,PROX1,FGFR1OP2,TOX,TUBB2B,LRRTM3,PTCH1,DNAJC6,LRP8,KCNC1,PTPRO,PTPRZ1,SRGAP3,ARNT2,NKAIN1,KIF2A,DPP6,DTNA,SFXN5,EPB41" Coexpression Atlas BM Top 100 - temporal lobe BM Top 100 - temporal lobe Body Map 1.19E-15 5.30E-12 2.39E-14 2.15E-13 23 75 "ERMN,HPCAL4,MOBP,FOXG1,SLC1A2,SNAP25,SCN3B,ARPP21,C11orf87,GPM6A,NRGN,VXN,VSTM2A,GRIA2,OPCML,FBXL16,PCDH8,PDE1A,CELF5,PLPPR4,KCNQ2,ELAVL4,C2orf80" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.30E-15 5.76E-12 2.58E-14 2.32E-13 49 357 "RTN1,FABP7,SCN3A,SEMA6A,ANK3,MAGI3,CCDC80,NSG2,PDE8B,SCG3,B3GAT1,SNAP25,DKK3,SCN3B,NMNAT2,NCAM1,SEPT3,NFIA,ARHGEF7,OS9,SYT4,GNG3,GNG4,ANO4,GPM6A,GPM6B,GRIA2,CELF3,PCDH9,DCLK1,RBFOX2,SCRG1,NRXN1,NEGR1,CELF5,ATCAY,NXPH1,CRMP1,DNAJC6,CEP170,STMN4,PTPRZ1,KCNJ4,KCNQ2,RALGDS,RTN4,CBLN2,ELAVL3,RCAN2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.44E-15 6.40E-12 2.86E-14 2.57E-13 29 127 "MAPT,CSMD3,RTN1,SLITRK1,FABP7,SCN3A,SLC7A14,CADPS,ASCL1,ASTN1,SNAP25,SCN3B,C11orf87,SYT4,GRIA1,INA,CDH10,DUSP26,CADM1,CNTN1,NRSN1,MAPK10,JAKMIP2,STMN4,PTPRO,KCNQ2,CALN1,ST8SIA3,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.46E-15 6.47E-12 2.86E-14 2.57E-13 26 100 "TTYH1,ADGRV1,SLITRK1,FABP7,LINC00461,FOXG1,SHTN1,ASCL1,SCG3,DLL3,ILDR2,FGF17,DIRAS1,HAP1,INA,CELF3,ADGRG1,JAM2,ATCAY,HES5,DPYSL5,JAKMIP2,STMN4,RFX4,ELAVL3,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.46E-15 6.47E-12 2.86E-14 2.57E-13 26 100 "ADGRV1,FABP7,LINC00461,FOXG1,ASCL1,SCG3,ATP1A3,ILDR2,GPM6A,GPM6B,CECR2,INA,CELF3,PAX6,CDH8,PRMT8,ADGRG1,JAM2,SEMA5B,PLCH2,DPYSL5,JAKMIP2,PTPRZ1,RFX4,ELAVL4,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.54E-15 6.85E-12 3.02E-14 2.71E-13 28 118 "TTYH1,APC2,ADGRV1,RTN1,FABP7,LINC00461,FOXG1,ASCL1,TAGLN3,B3GAT1,SNAP25,LHFPL4,NPAS3,ACSBG1,DCLK2,GPM6A,GPM6B,HAP1,GRIK2,CELF3,ADGRG1,NCAN,HES5,DPYSL5,STMN4,SRGAP3,ELAVL3,OLIG2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.73E-15 7.69E-12 3.37E-14 3.03E-13 24 84 "EYA1,CSMD3,RTN1,FABP7,CADPS,SCG3,SNAP25,SCN3B,NCAM1,GFRA1,SEPT3,ASTN2,INA,DCLK1,SERPINE2,CADM1,CRMP1,FEZ1,NRSN1,MAPK10,STMN4,L1CAM,RET,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.96E-15 8.72E-12 3.81E-14 3.42E-13 42 271 "APC2,MEG3,SLITRK1,CHST15,LRRTM4,ZCCHC17,NLGN1,CCDC88A,TAGLN3,ASTN1,B3GAT1,NRG3,NPAS3,NASP,NFIA,RHBDL3,SEMA4A,DIRAS1,VSTM2A,PSD3,MFSD2A,CDK11B,PCDH9,CDH8,PDE1A,ADGRG1,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,FEZ1,FMN2,NOS1AP,BRINP3,TOX,SPIRE1,JAKMIP2,LRP8,DTNA,EPB41,EPB41L1" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.99E-15 8.84E-12 3.84E-14 3.45E-13 27 110 "FABP7,DRAXIN,LINC00461,NSG2,CADPS,ASCL1,TAGLN3,DLL3,SNAP25,SOX5,DNER,NAP1L2,NEUROD1,PCDH8,DCLK1,PRMT8,CADM1,CRMP1,MAPK10,HES5,KIAA0408,JAKMIP2,PTPRZ1,SLC17A6,VANGL2,ELAVL3,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 2.49E-15 1.11E-11 4.79E-14 4.30E-13 38 225 "DPF1,MBP,RTN3,RTN1,ADCYAP1R1,FABP7,LINC00461,SOX6,PPM1E,APBB1,ASCL1,SCG3,B3GAT1,SNAP25,ATP1A3,PHYHIPL,KIF1B,NPAS3,ACSBG1,GNG3,GPM6A,GPM6B,DDR1,ZEB1,HAP1,MFSD2A,CDH8,JAM2,NRXN2,SEMA5B,CTNND2,PROX1,TUBB2B,JAKMIP2,ELMO1,PTPRZ1,SRGAP3,ELAVL4" Coexpression Atlas PCBC_ECTO_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 2.56E-15 1.14E-11 4.90E-14 4.39E-13 89 986 "MAP6,CDHR1,TMEM74,ADGRV1,FABP7,ERMN,GRAMD1B,ADORA1,SLC30A10,SESN3,SLC1A6,BCO1,LRRC55,PKNOX2,ASCL1,SCG3,SLIT1,DDX25,ASTN1,B3GAT1,PHYHIPL,SOX10,ILDR2,NMNAT2,SALL3,LHFPL4,LMO3,COLGALT2,STOX1,NELL1,NHLH1,UNC5D,CNTN2,PRUNE2,GPM6A,VWC2,CAMK2A,GRIA1,GRIA4,GRM3,CELF3,KCNK10,PAX6,IGSF21,CDH8,LGI1,FNDC5,HAPLN2,CA14,TMEFF2,FAM181B,CELF5,COL9A2,NECAB2,ATCAY,BTBD17,POU3F2,NKAIN4,KCNT2,RAB39A,PLD5,IGSF1,CTNND2,HES5,PROX1,KLK6,RIMS3,DPYSL5,ANKS1B,TUBB2B,ZNF385B,CA10,CADM2,STMN4,KCNA1,OLFM3,PTPRD,KCND3,KCNJ4,KCNN3,KCNQ2,HS3ST4,DNAH9,TMEM255A,DPP6,RFX4,RGS7,RLBP1,LMO1" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.59E-15 1.15E-11 4.94E-14 4.44E-13 88 969 "TTYH1,EPS8,APC2,EMID1,ACTN2,MEG3,IL17D,NDRG2,F3,RTN1,ADCY2,CHST15,LRRTM4,FOXG1,ANK1,DOCK10,NTNG1,CCDC80,NLGN1,SLC1A2,MSR1,SLC6A9,ASCL1,TAGLN3,ASTN1,NRG3,TNIK,JPH4,ARPP21,ADGRB2,NPAS3,SMOC1,NELL1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,GNG4,UNC5D,ADGRL3,CACNA1A,GPM6B,CLEC9A,CECR2,VSTM2A,PSD3,GRIK2,MFSD2A,REPS2,PCDH9,CDH8,PDE1A,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,COL9A2,PRRX1,FAT3,NXPH1,NKAIN4,FEZ1,FMN2,MAPK10,BRINP3,ZBTB16,TOX,PMEPA1,CADM2,LRP8,STMN4,PTPRD,CCDC3,PCDH15,KCNN3,DLG2,BEND5,DTNA,ABCC9,EFNA3,VWA5A,EPB41L1,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 200 GSE76381_iPSMoleculeCountsPMLog2 3.17E-15 1.41E-11 6.02E-14 5.41E-13 54 434 "RTN1,FABP7,SCN3A,SEMA6A,ANK3,MAGI3,CCDC80,CCDC88A,NSG2,PDE8B,SCG3,B3GAT1,SNAP25,DKK3,SCN3B,NMNAT2,FXYD6,NCAM1,SEPT3,NFIA,ARHGEF7,OS9,SYT4,GNAS,GNG3,GNG4,ANO4,GPM6A,GPM6B,GRIA2,INA,CELF3,PCDH9,DCLK1,RBFOX2,SCRG1,NRXN1,NEGR1,CELF5,ATCAY,NXPH1,CRMP1,TUBB2B,DNAJC6,CEP170,STMN4,PTPRZ1,KCNJ4,KCNQ2,RALGDS,RTN4,CBLN2,ELAVL3,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 3.78E-15 1.68E-11 7.15E-14 6.42E-13 47 340 "TTYH1,APC2,MEG3,ADGRV1,RTKN,SLITRK1,FABP7,LRRTM4,FOXG1,SEMA6C,ASRGL1,SHTN1,ASCL1,TAGLN3,ATP2B2,SOX5,LHFPL4,KIF1B,NPAS3,RHBDL3,ASTN2,DCLK2,SEMA4A,GPM6B,ACSL6,DIRAS1,HAP1,VSTM2A,PSD3,GRIK2,CELF3,ADGRG1,TUB,CELF5,SPATA6,ATCAY,CRMP1,NCAN,MAPK10,HES5,BRINP3,DPYSL5,STMN4,DTNA,L1CAM,ELAVL3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.90E-15 1.73E-11 7.35E-14 6.60E-13 22 71 "TTYH1,ADGRV1,NDRG2,ADCY2,FABP7,LINC00461,C1orf61,BCAN,ATP1A2,DKK3,NFIA,MLC1,GPM6B,SCRG1,PMP2,NKAIN4,NCAN,HES5,PTPRZ1,DPP6,RFX4,FGFBP3" Coexpression Atlas PCBC_SC_500 Progenitor-Cell-Biology-Consortium_StemCell_top-relative-expression-ranked_500 PCBC 5.24E-15 2.33E-11 9.82E-14 8.81E-13 58 497 "TMEM74,SYNDIG1,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,PDZD4,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,SEPT3,ACSBG1,RHBDL3,GNG4,GPM6A,GPM6B,CECR2,TMEM151B,SYT6,GRIA4,GRM3,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,FGFBP3,LINC00599,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.43E-15 2.41E-11 1.01E-13 9.06E-13 22 72 "TTYH1,NDRG2,FABP7,LINC00461,C1orf61,BCAN,ATP1A2,GFAP,INKA2,NFIA,DCLK2,WSCD1,GPM6B,SCRG1,PMP2,NCAN,SDC3,HES5,PTPRZ1,OLIG1,FGFBP3,OLIG2" Coexpression Atlas BM Top 100 - frontal lobe BM Top 100 - frontal lobe Body Map 5.43E-15 2.41E-11 1.01E-13 9.06E-13 22 72 "FOXG1,SLC1A2,SNAP25,SCN3B,ARPP21,C11orf87,GPM6A,NRGN,VXN,VSTM2A,GRIA2,OPCML,FBXL16,PCDH8,KIAA1549L,CABP1,CELF5,RIMS3,KCNJ4,KCNQ2,ELAVL4,C2orf80" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 5.50E-15 2.44E-11 1.02E-13 9.13E-13 35 196 "TTYH1,APC2,ADGRV1,SLITRK1,FOXG1,ASRGL1,SHTN1,SLC1A2,NSG2,TAGLN3,DLL3,FYN,ATP2B2,LHFPL4,NPAS3,DCLK2,WSCD1,ACSL6,DIRAS1,GRIK2,CELF3,ADGRG1,TUB,GDAP1L1,CELF5,ATCAY,CRMP1,NCAN,MAPK10,HES5,DPYSL5,STMN4,DTNA,ELAVL3,OLIG2" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500 Gudmap RNAseq 6.71E-15 2.98E-11 1.24E-13 1.11E-12 126 1686 "TTYH1,EPS8,SERPINA3,ACER3,RIMKLA,ACHE,ACLY,MEG3,NDRG2,ADCY2,WAC,FABP7,SORCS1,GRAMD1B,SNX30,CHST15,LRRTM4,SEMA6C,SGIP1,CDC42BPA,CNIH2,PKP4,DOCK10,NTNG1,GAS7,CCDC80,CACHD1,NLGN1,ST8SIA1,CLSTN1,ZNF365,KIAA1614,SLC6A9,SLC14A1,CADPS,PDE8B,ASTN1,TMEM151A,NRG3,PALLD,DKK3,MYBPC1,TNIK,ZCCHC24,MYH7,B4GALNT1,ADAM15,ADGRB2,NCAM1,COLGALT2,INKA2,NELL1,ACSBG1,NFIA,C1QC,GNG3,ADGRL3,CACNA1A,GPM6A,CACNB2,GPR19,TCF12,AZIN2,DDR2,BRSK2,PSD3,GRIA4,USP2,P2RX7,TIE1,GUCY1A1,DAAM2,CDK11B,TNS1,DCLK1,TPM4,PDE1A,TMEFF2,JAM2,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,CPT1C,FTO,PRRX1,SLC36A4,IFFO1,FAT3,CP,SNCAIP,TENM4,NKAIN4,KCNT2,FEZ1,VCAN,BRINP3,TOX,ANKS1B,TUBB2B,LRRTM3,DNAJC6,ELMO1,LRP8,RGMA,PTPRD,KCNA6,PTPRE,KCNC1,KCND3,PTPRZ1,CCDC3,KCNK1,TMEM255A,ATN1,FAM13C,BEND5,SSPN,CACNG7,PIANP,EFNA3,VWA5A,ELAVL4,PLEKHO1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 9.04E-15 4.01E-11 1.66E-13 1.49E-12 21 66 "MAP6,RTN1,SCG3,TAGLN3,DLL3,B3GAT1,DNER,NFASC,NCAM1,NHLH1,SYT4,GNG3,CNTN2,ZEB1,INA,FNDC5,ADGRG1,POU3F2,SLC17A6,RALGDS,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.03E-14 4.59E-11 1.89E-13 1.69E-12 22 74 "TTYH1,ADGRV1,NDRG2,FABP7,LINC00461,C1orf61,BCAN,ATP1A2,NFIA,GPM6B,TCF12,PSD3,SCRG1,JAM2,PMP2,FAT3,TENM4,NCAN,HES5,LRP8,PTPRZ1,FGFBP3" Coexpression Atlas ratio_EB_vs_SC_1000_K5 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 1.05E-14 4.68E-11 1.92E-13 1.72E-12 52 418 "C1orf194,MAP6,RTN1,AMER2,LINC00461,SOX6,LRRC4C,NSG2,DACH2,ASCL1,SLIT1,TAGLN3,ADGRA1,SNAP25,PHYHIPL,SCN3B,ILDR2,ENKUR,TTLL9,TTC9B,CPLX2,NPAS3,NELL1,NHLH1,SYT4,MYRF,CDK5R2,CNTN2,GRIA2,TF,OLR1,GUCY1A1,CELF3,PAX6,LGI1,SCRG1,FAM181B,POU3F2,HES5,ITIH2,STMN4,KCNA2,CDH20,CCDC3,SLC17A6,FAM13C,RFX4,SLC39A12,ELAVL3,ELAVL4,RPE65,PRRT4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.16E-14 5.14E-11 2.10E-13 1.88E-12 28 127 "ADGRV1,RTN1,SLITRK1,FABP7,TUBB4A,DLL3,AHCYL1,FGF17,WSCD1,ACSL6,GPR19,HAP1,GRIK3,INA,CELF3,ADGRG1,NLGN3,NRXN2,CELF5,ATCAY,CRMP1,NCAN,MAPK10,HES5,PROX1,DPYSL5,SRGAP3,DTNA" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.23E-14 5.47E-11 2.22E-13 2.00E-12 43 298 "CLIP1,KLHL32,RTN1,LINC00461,SOX6,PPM1E,SCG3,ASTN1,B3GAT1,SNAP25,PHYHIPL,ILDR2,NPAS3,NASP,GNG3,CACNA1A,GPM6A,TCF7L2,PTBP2,MFSD2A,TJP1,CDK11B,MAGI1,PRMT8,JAM2,KIAA1549L,NRXN2,SEMA5B,FAT3,ACBD5,FMN2,CTNND2,PROX1,TUBB2B,JAKMIP2,PTPRD,SRGAP3,KCNN3,RFX4,EFNA3,ELAVL4,EPB41,LRRC23" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k3 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.60E-14 7.11E-11 2.88E-13 2.59E-12 39 250 "ABAT,CDHR1,MEG3,MRVI1,ADCY2,ANK2,ST8SIA1,RUFY2,SLC14A1,DACH2,GPR153,SORCS3,DKK3,NEK6,KIF1B,ADGRB2,DNER,NCAM1,SYT4,ADGRL3,ANO4,TBX15,DDR2,VSTM2A,GRIA1,GRIA4,GRM3,DCLK1,LGI1,PDE1C,TMEFF2,NEGR1,CNTN1,PRRX1,KCNA1,NTM,AK5,TTLL7,EFNA3" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K5 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.65E-14 7.34E-11 2.96E-13 2.66E-12 24 92 "MBP,ADGRV1,RTN1,LINC00461,FOXG1,SHTN1,ASCL1,SNAP25,ATP1A3,GAD2,GPM6A,HAP1,GRIK2,MFSD2A,CELF3,ADGRG1,GDAP1L1,MAPK10,HES5,DPYSL5,STMN4,DTNA,ELAVL3,OLIG2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.76E-14 7.83E-11 3.14E-13 2.82E-12 28 129 "EYA1,FABP7,SCN3A,UNC79,SGIP1,ANK2,CADPS,SCG3,SNAP25,PHYHIPL,SCN3B,NAP1L2,SYT4,GRIA2,GRIA4,INA,PCDH9,CADM1,NRXN1,KIAA0408,JAKMIP2,KCNA4,PTPRZ1,SRGAP3,DLG2,ST8SIA3,RGS7,ELAVL4" Coexpression Atlas PCBC_SC_CD34+_500 Progenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_500 PCBC 1.77E-14 7.86E-11 3.14E-13 2.82E-12 57 496 "ADGRV1,ADCY2,GALNT13,RYR1,FABP7,NLGN4X,SEMA6A,PDZD4,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,IGSF9B,SALL3,LHFPL4,SEPT3,ACSBG1,SYT4,GNG4,NODAL,GPM6B,CECR2,TMEM151B,SYT6,BRSK2,GRIA4,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,A2ML1,CABP1,CELF5,PACSIN1,ATCAY,BTBD17,KCNT2,ATRNL1,RIMS4,RAB39A,PLD5,IGSF1,CADM2,KCNQ2,NKAIN1,HS3ST4,CALN1,FAM57B,FGFBP3,LINC00599,SEZ6" Coexpression Atlas BM Top 100 - parietal lobe BM Top 100 - parietal lobe Body Map 1.92E-14 8.52E-11 3.40E-13 3.05E-12 22 76 "ERMN,MOBP,FOXG1,SLC1A2,SNAP25,SCN3B,C11orf87,NRGN,VSTM2A,GRIA2,OPCML,PCDH8,PDE1A,KIAA1549L,CABP1,CELF5,RIMS3,KCNJ4,KCNMA1,KCNQ2,ELAVL4,C2orf80" Coexpression Atlas PCBC_SC_fibroblast_500 Progenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 1.93E-14 8.57E-11 3.40E-13 3.05E-12 57 497 "TMEM74,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,PDZD4,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,SALL3,LHFPL4,SEPT3,ACSBG1,GNG4,UNC5D,GPM6A,GPM6B,CECR2,TMEM151B,SYT6,GRIA4,GRM3,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CA14,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CABP1,CELF5,PACSIN1,ATCAY,BTBD17,NKAIN4,KCNT2,ATRNL1,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,CALN1,FAM57B,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Arv_EB-LF_500 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500 PCBC 2.30E-14 1.02E-10 4.03E-13 3.62E-12 57 499 "SERPINA3,MAPT,FABP7,AGT,LINC00461,ACTL6B,HPCAL4,C1orf61,NSG2,SCG3,SLIT1,SLN,B3GAT1,TMEM151A,PHYHIPL,GAD2,DNER,GFAP,NELL1,MLC1,C1QC,SYT4,MYRF,CNTN2,GPM6A,CAMK2A,GRIA2,GRIA4,TF,OLR1,GUCY1A1,CELF3,PAX6,PCDH8,LGI1,SCRG1,HPSE2,GDAP1L1,CELF5,PRRX1,POU3F2,NKAIN4,ATRNL1,NCAN,KIAA1755,PLPP4,DPYSL5,STMN4,PTPRO,KCNQ2,SLC17A6,DPP6,RFX4,ELAVL3,ELAVL4,C2orf80,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 2.60E-14 1.15E-10 4.54E-13 4.07E-12 22 77 "RTN1,SLITRK1,ACTL6B,ANK3,NSG2,ASTN1,B3GAT1,SCN3B,NCAM1,LMO3,SEPT3,GNG4,INA,CELF3,KCNK10,CHGA,NEGR1,TENM4,CADM2,SLC17A6,BSDC1,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.80E-14 1.24E-10 4.87E-13 4.37E-12 34 195 "RTN1,SCN3A,ANK3,NSG2,SCG3,SNAP25,DKK3,SCN3B,NMNAT2,NCAM1,SEPT3,ARHGEF7,SYT4,GNG3,GNG4,GPM6A,GRIA2,CELF3,PCDH9,DCLK1,RBFOX2,NRXN1,NEGR1,CELF5,ATCAY,CRMP1,DNAJC6,CEP170,STMN4,RALGDS,RTN4,CBLN2,ELAVL3,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.05E-14 1.36E-10 5.30E-13 4.76E-12 16 36 "MEG3,RTN1,FABP7,SCN3A,C1orf61,NSG2,ASCL1,MYT1L,NCAM1,GPM6A,GRIA2,GRIA4,INA,NRXN2,ELAVL4,EN2" Coexpression Atlas BM Top 100 - accumbens BM Top 100 - accumbens Body Map 3.49E-14 1.55E-10 6.04E-13 5.42E-12 22 78 "MEG3,ELMOD1,FOXG1,SLC1A2,NSG2,GAD2,ARPP21,NCDN,CACNA1E,NRGN,GPR88,PTPN5,FBXL16,PCDH8,PDYN,HPCA,CELF5,PLPPR4,KCNJ4,KCNQ2,ST8SIA3,C2orf80" Coexpression Atlas PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.68E-14 1.63E-10 6.33E-13 5.68E-12 86 979 "TTYH1,TMEM74,CNTNAP3,WLS,FABP7,TESK2,FHL1,CNIH2,APBA2,APBB1,SESN3,CCDC80,DGKD,TACC2,NLGN1,ST3GAL3,BCO1,PKNOX2,GPR153,ASPH,ASTN1,ALDH4A1,ATP1A2,FYN,PALLD,WDTC1,SOX1,CADM3,ILDR2,ZSWIM8,ADAM15,NAP1L2,COLGALT2,STOX1,SMOC1,GPR162,RGL1,PHLDB1,RND1,VAMP1,UNC5D,ADGRL3,WSCD1,GPR19,TCF12,PCDHGA3,NUMA1,INA,KCNK10,PAX6,IGSF21,CDH8,LGI1,CIART,FNDC5,ADGRG1,TUB,NLGN3,CPT1C,TJP2,CCDC136,SLC25A27,MICAL1,ATCAY,POU3F2,CRMP1,NKAIN4,DZIP3,CTNND2,HES5,FAM131B,ZBTB16,RIMS3,DPYSL5,ZNF385B,OLFM3,PTPRZ1,SV2A,ARNT2,CAB39L,BEND5,RGS10,ARHGEF10L,CACNG7,PIANP,BAALC" Coexpression Atlas BM Top 100 - thalamus BM Top 100 - thalamus Body Map 4.13E-14 1.83E-10 7.08E-13 6.35E-12 20 63 "MAG,ERMN,MOBP,MOG,NTNG1,AQP4,C11orf87,GFAP,CNDP1,TCF7L2,TF,OPCML,INA,ANLN,CCDC136,P2RY12,RIMS3,OLIG1,SLC17A6,OLIG2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k1 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.65E-14 2.07E-10 7.94E-13 7.13E-12 24 96 "MAPT,RTN1,ASCL1,SNAP25,SCN3B,DNER,C11orf87,PCDH11X,GRIA1,INA,CDH10,PIRT,TMEFF2,DUSP26,MAPK10,TUBB2B,JAKMIP2,STMN4,PTPRO,KCNQ2,HS3ST4,CALN1,RET,ELAVL4" Coexpression Atlas ratio_SC_vs_ECTO_2500_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 5.64E-14 2.51E-10 9.60E-13 8.62E-12 79 865 "DPF1,RIMKLA,CSMD2,ADCY2,SLITRK1,GALNT13,ADCYAP1R1,RYR1,SORCS1,TUBB4A,NLGN4X,HPCAL4,PDZD4,BCAN,JAKMIP3,SHANK2,SCG3,CSPG5,DDX25,IGSF9B,SNCB,MEGF11,JPH4,LHFPL4,SEPT3,AJAP1,RHBDL3,GNG4,NODAL,KLHL4,GPM6B,ACSL6,TMEM151B,SYT6,VSTM2A,GRIN1,ADAMTS8,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,DCLK1,HRH3,CHGA,GDAP1L1,CAMKV,CPT1C,BTF3L4,SLC36A4,FAT3,ATCAY,POU3F4,VCAN,RIMS4,IGSF1,TOX,PHYHIP,PLPPR5,LRRTM3,JAKMIP2,MAGI2,PARD6A,PTPRZ1,RABGAP1L,NAV2,KCNQ2,NKAIN1,SLC25A48,CALN1,RET,ST8SIA3,SFXN5,CACNG7,FGFBP3,ARHGAP12,LINC00599,C2orf80,SEZ6" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 5.73E-14 2.55E-10 9.72E-13 8.72E-12 29 145 "ADGRV1,RTN1,SLITRK1,LRRTM4,FHL1,FOXG1,SHTN1,PHYHIPL,ILDR2,NASP,LMO3,GNG3,ACSL6,TCF7L2,HAP1,GRIK2,CELF3,PAX6,PRMT8,NRXN2,ATCAY,CRMP1,NCAN,MAPK10,HES5,DPYSL5,JAKMIP2,PTPRZ1,DTNA" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 6.99E-14 3.11E-10 1.18E-12 1.06E-11 49 395 "TTYH1,APC2,ADGRV1,FHL1,FOXM1,SHTN1,NSG2,DLL3,ATM,PHYHIPL,ATP2B2,SON,SOX5,ILDR2,LMO3,SEPT3,GNG3,WWC1,WSCD1,TCF7L2,DIRAS1,HAP1,GRIK2,CELF3,PAX6,PRMT8,TUB,KIAA1549L,NRXN2,NMT2,MEAF6,NSD2,CRMP1,NCAN,CTNND2,HES5,PROX1,DPYSL5,JAKMIP2,ELMO1,SMG7,PTPRZ1,DTNA,RTN4,L1CAM,RFX4,ABI2,ELAVL3,OLIG2" Coexpression Atlas ratio_SC_vs_DE_1000_K4 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 7.55E-14 3.35E-10 1.27E-12 1.14E-11 46 354 "TTYH1,CEND1,RYR1,ACTL6B,HPCAL4,SLITRK3,BCAN,LRRC55,KIF21B,JPH4,LMO3,RND1,SEPT3,RHBDL3,PCDH11X,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRIN1,ZDHHC22,PAH,HRH3,CHGA,CHRNB2,NLGN3,CAMKV,CNTN1,BTBD17,POU3F4,NKAIN4,RIMS4,RAB39A,PRKCG,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRZ1,KCNN3,CACNG7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_500 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_500 FaceBase_ST1 8.30E-14 3.69E-10 1.39E-12 1.25E-11 50 411 "TTYH1,ACER3,MAP6,FABP7,LINC00461,FOXG1,PKNOX2,MT3,NSG2,ASCL1,SCG3,TAGLN3,TTC9B,NAP1L2,NPAS3,SPART,GPR162,FGF17,NFIA,DCLK2,GPM6A,GPM6B,FAM69C,DDR1,TCF12,PTBP2,FBXL16,INA,IGSF21,ADGRG1,JAM2,DUSP26,GDAP1L1,SPATA6,ATCAY,ACBD5,CRMP1,NKAIN4,FEZ1,MAPK10,HES5,TUBB2B,JAKMIP2,SHD,OLIG1,ABI1,LMO1,ELAVL3,OLIG2,LRRC23" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 8.36E-14 3.71E-10 1.40E-12 1.25E-11 66 655 "DPF1,ACLY,KLHL32,SEMA6A,FHL1,SOX6,CDC42BPA,PPM1E,NLGN1,LRRC4C,MADD,MSR1,SCG3,ASTN1,B3GAT1,ADGRA1,PHYHIPL,ILDR2,NPAS3,NASP,NCAM1,LMO3,GFRA1,GNG3,CACNA1A,PTBP2,GRIK4,CDK11B,PAX6,PCDH9,CDH8,MAGI1,PDE1A,PDE3B,PRMT8,JAM2,HPCA,KIAA1549L,NRXN1,NRXN2,SEMA5B,NEGR1,FLRT1,FAM181B,FAT3,CRLS1,FEZ1,ATRNL1,FMN2,IGSF1,CTNND2,ZBTB16,TOX,SPIRE1,TUBB2B,JAKMIP2,LRP8,PTPRD,PTPRZ1,KCNN3,RFX4,CACNG7,EFNA3,ELAVL4,BSCL2,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.64E-14 3.84E-10 1.44E-12 1.29E-11 21 73 "ASIC1,MEG3,RTN1,SCN3A,APC,NSG2,TAGLN3,MYT1L,KIF21B,GAD2,DNER,NCAM1,SEPT3,GPM6A,GRIA2,INA,RBFOX2,CELF5,PANTR1,ELAVL3,ELAVL4" Coexpression Atlas PCBC_ratio_EB_vs_SC_1000 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000 PCBC 1.02E-13 4.54E-10 1.69E-12 1.52E-11 86 997 "SERPINA3,C1orf194,MAP6,MAPT,WLS,RTN1,RXRG,AMER2,AGT,SCN3A,LINC00461,SOX6,CCDC80,SYBU,LRRC4C,NSG2,DACH2,ASCL1,SLIT1,TAGLN3,SLN,ADGRA1,SNAP25,PHYHIPL,SCN3B,MYBPC1,ILDR2,ENKUR,TTLL9,TTC9B,CPLX2,NPAS3,NCAM1,GFRA1,NELL1,NHLH1,SYT4,DCLK2,MYRF,CDK5R2,CNTN2,NPPA,ZEB1,AZIN2,CAMK2A,DDR2,GRIA2,TF,OLR1,GUCY1A1,CELF3,PAX6,TNS1,LGI1,PDE1A,PDE1C,FNDC5,ADGRG1,SCRG1,FAM181B,PRRX1,POU3F2,CSF3R,PLCH2,PHACTR3,KIAA1755,PLPP4,HES5,ZBTB16,PTHLH,ITIH2,STMN4,KCNA2,CDH20,KCND3,CCDC3,SLC17A6,FAM13C,RFX4,SLC39A12,CBLN2,ELAVL3,ELAVL4,RPE65,TMEM100,PRRT4" Coexpression Atlas PCBC_ctl_geo-heart_1000 geo_heart_top-relative-expression-ranked_1000 PCBC 1.02E-13 4.54E-10 1.69E-12 1.52E-11 86 997 "SERPINA3,MAPT,DUSP27,RCSD1,SYNDIG1,ACTN2,KCNIP2,NDRG2,RXRG,HHATL,ADORA3,LCNL1,HOGA1,AGT,SCN4B,FGF1,FGR,ANK1,PI16,SORBS1,SLC1A7,MT3,SLC14A1,SPHKAP,SLN,KBTBD12,IGSF9B,ATP1A2,ATP1A3,DKK3,MYBPC1,B3GALT2,MYH7,IDI2-AS1,NCAM1,ALDH1L1,GFAP,ADHFE1,ABCC8,C1QC,FAM69C,VWC2,NPPA,CACNB2,GPR17,DIRAS1,CAMK2A,PCDHGA3,VXN,TF,USP2,GUCY1A1,TNS1,PDE1A,PDE1C,PDE2A,FNDC5,HAPLN2,ANO5,CHI3L2,MS4A7,DUSP26,PHKG1,HPR,CABP1,PRRX1,PACSIN1,ETNPPL,CSF3R,PHACTR3,KIAA1755,CMTM5,PROX1,MASP1,DKFZp779M0652,SHD,KCND3,KCNJ4,KCNJ11,PYGM,SUSD4,CRTAC1,EEF1A2,SSPN,RCAN2,RASGRP2" Coexpression Atlas ratio_SC_vs_MESO_500_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 1.33E-13 5.92E-10 2.19E-12 1.97E-11 19 59 "TTYH1,CEND1,ACTL6B,HPCAL4,LRRC55,TMEM151A,SOX1,DNER,LMO3,CNTN2,TMEFF2,NRXN2,KLK6,DPYSL5,PTPRO,NTM,AK5,KCNMA1,ATL1" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.54E-13 6.86E-10 2.52E-12 2.27E-11 84 969 "EPS8,APC2,EMID1,ACTN2,MEG3,ADGRV1,IL17D,SLC25A25,NDRG2,ADCY2,CHST15,LRRTM4,ANK1,DOCK10,NTNG1,CCDC80,NLGN1,SLC1A2,MSR1,SLC6A9,TAGLN3,ASTN1,NRG3,ZSWIM8,JPH4,ARPP21,ADGRB2,NPAS3,NELL1,ACSBG1,NFIA,RHBDL3,PCDH11X,C1QC,ASTN2,SEMA4A,UNC5D,ADGRL3,CACNA1A,GPM6B,CLEC9A,CECR2,VSTM2A,PSD3,GRIK2,MFSD2A,PAX6,REPS2,PCDH9,CDH8,PDE1A,CA14,NLGN3,SERPINE2,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,COL9A2,NECAB2,FAT3,NXPH1,POU3F4,NKAIN4,FEZ1,FMN2,MAPK10,BRINP3,ZBTB16,TOX,PMEPA1,CADM2,LRP8,STMN4,CCDC3,PCDH15,KCNN3,DLG2,DTNA,ABCC9,VWA5A,EPB41L1,BAALC" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.55E-13 6.86E-10 2.52E-12 2.27E-11 20 67 "MEG3,RTN1,AMER2,SCN3A,ANK3,NSG2,SCN3B,MYT1L,KIF21B,NCAM1,CLASP2,GFRA1,GPM6A,INA,PCSK2,TMEFF2,KIAA0408,NTM,ELAVL4,EN2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.57E-13 6.95E-10 2.55E-12 2.29E-11 21 75 "EYA1,RTN1,ADCYAP1R1,FABP7,TUBB4A,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,GNG3,INA,CELF3,TMEFF2,GDAP1L1,MAPK10,PROX1,STMN4,DLG2,L1CAM,ELAVL4" Coexpression Atlas PCBC_DE_fibroblast_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_1000 PCBC 1.57E-13 6.98E-10 2.55E-12 2.29E-11 85 987 "ACHE,TMEM74,ADGRV1,ADARB2,ADCY2,RXRG,GALNT13,FABP7,SORCS1,ERMN,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,SH3GL2,SLC7A14,SLC1A6,SLC8A2,SCG3,SLCO1A2,DDX25,B3GAT1,SOX5,SOX10,SALL3,LHFPL4,RCOR2,FGF17,CASTOR3,SYT4,NODAL,MYRF,KLHL4,GPM6A,GPM6B,CECR2,GRIA4,GRIK3,GRM3,CCKBR,LEFTY2,USP2,C1orf94,CDH8,CDH10,SEZ6L,LGI1,TPD52,PCSK2,CA14,CHGA,SERPINE2,SEMA5B,A2ML1,CELF5,COL9A2,PACSIN1,ETNPPL,TENM4,KCNT2,ATRNL1,NCAN,RIMS4,FMN2,PLPP4,PLD5,PRKCZ,IGSF1,MAPK10,RIMS3,ANKS1B,TUBB2B,CADM2,CDH20,PTPRD,KCNQ2,HS3ST4,SLC25A48,CALN1,RET,FGFBP3,ELAVL4,C2orf80" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.69E-13 7.49E-10 2.72E-12 2.45E-11 45 348 "MAP6,RTN1,SCN3A,ANK2,ANK3,GPR153,SCG3,TAGLN3,DLL3,KIF21B,NMNAT2,DNER,NFASC,NCAM1,CLASP2,NEUROD1,ARHGEF7,NHLH1,SYT4,GNG3,CNTN2,ZEB1,INA,CELF3,RBFOX2,FNDC5,GDAP1L1,CAMKV,NECAB2,ATCAY,POU3F2,CRMP1,CTNND2,MAPK8,RIMS3,PTCH1,STMN4,SLC17A6,FAM57B,RALGDS,L1CAM,RGS10,ELAVL3,ELAVL4,EPB41" Coexpression Atlas Arv_SC_fibroblast_500_K1 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 1.82E-13 8.08E-10 2.93E-12 2.63E-11 39 269 "RIMKLA,ADGRV1,FABP7,NLGN4X,PDZD4,PPM1E,SLC1A6,SCG3,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,PCDH11X,SYT6,GRIA4,GRM3,ZDHHC22,IGSF21,C1orf94,CHGA,GDAP1L1,CAMKV,CELF5,ATCAY,BTBD17,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,USH1C,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_100 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_100 FaceBase_ST1 1.88E-13 8.34E-10 3.01E-12 2.70E-11 22 84 "FABP7,LINC00461,FOXG1,MT3,ASCL1,SCG3,TAGLN3,TTC9B,NPAS3,NFIA,GPM6A,INA,JAM2,GDAP1L1,NKAIN4,HES5,TUBB2B,JAKMIP2,OLIG1,LMO1,ELAVL3,OLIG2" Coexpression Atlas PCBC_DE_1000 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000 PCBC 1.96E-13 8.72E-10 3.14E-12 2.81E-11 85 991 "CDHR1,TMEM74,ADGRV1,CSMD2,ADCY2,RXRG,GALNT13,FABP7,SORCS1,ERMN,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,CNIH2,CACHD1,SHTN1,SLC7A14,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,SOX10,SALL3,LHFPL4,STOX1,FGF17,SYT4,NODAL,KLHL4,GPM6A,GPM6B,CECR2,SYT6,BRSK2,CCKBR,LEFTY2,USP2,IGSF21,C1orf94,CDH10,DCLK1,SEZ6L,LGI1,CA14,ANO5,CHGA,PLEKHB1,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CELF5,PACSIN1,FAT3,ETNPPL,TENM4,KCNT2,ATRNL1,NCAN,RIMS4,FMN2,RAB39A,PLPP4,RIMS3,ANKS1B,TUBB2B,CADM2,SHD,RGMA,CDH20,PTPRD,KCNQ2,NKAIN1,HS3ST4,TMEM255A,SLC25A48,CALN1,SLC25A18,RET,FGFBP3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 40 GSE76381_iPSMoleculeCountsPMLog2 1.98E-13 8.80E-10 3.15E-12 2.83E-11 24 102 "RTN1,SEMA6A,ANK3,NLGN1,NSG2,SNAP25,FYN,DKK3,SCN3B,KIF21B,JPH4,SEPT3,SYT4,INA,CELF3,PCDH9,NEGR1,DNAJC12,CELF5,FAT3,TOX,KIAA0513,ELAVL3,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.11E-13 9.39E-10 3.34E-12 3.00E-11 20 68 "MEG3,RTN1,SCN3A,LINC00461,ANK3,NSG2,TAGLN3,MYT1L,NCAM1,GPM6A,INA,ZDHHC22,ADGRG1,NEGR1,SF1,KIAA0408,NTM,LINC00599,ELAVL4,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.11E-13 9.39E-10 3.34E-12 3.00E-11 20 68 "ASIC1,MEG3,RTN1,FABP7,SCN3A,C1orf61,SGIP1,NSG2,ASCL1,MYT1L,NCAM1,GPM6A,GRIA2,GRIA4,INA,NRXN2,HES5,PAK5,ELAVL4,EN2" Coexpression Atlas PCBC_ratio_ECTO UCB CD34+Z_vs_ECTO blastocyst_cfr-2X-p05 ECTO UCB CD34+Z_vs_ECTO blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.24E-13 9.95E-10 3.53E-12 3.17E-11 42 310 "TTYH1,EMID1,TMEM74,PLEKHG5,DRAXIN,C1QTNF4,GPR153,DDX25,PHYHIPL,SOX1,SALL3,NEK6,NCAM1,SMOC1,SEPT3,NHLH1,ROBO3,MYRF,GPM6A,CROCCP2,PTPN5,CELF3,HPSE2,CAMKV,SEMA5B,CCDC136,POU3F2,NKAIN4,FEZ1,ARHGEF4,HES5,ZNF385B,PTCH1,RGMA,CDH20,PTPRZ1,SRGAP3,KCNJ4,RAD52,FAM57B,RLBP1,CACNG7" Coexpression Atlas ratio_ECTO_vs_SC_2500_K3 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 2.32E-13 1.03E-09 3.65E-12 3.27E-11 77 854 "C1orf194,MAP6,CEND1,ECSIT,WLS,KCNIP2,ACTL6B,SLC30A10,HPCAL4,SOX6,SESN3,BCO1,PKNOX2,NSG2,ASCL1,SLIT1,TAGLN3,B3GAT1,SNAP25,PHYHIPL,SOX1,SOX5,SOX10,ILDR2,FXYD6,NCAM1,LMO3,COLGALT2,STOX1,SMOC1,GPR162,NEUROD1,PCDH11X,NHLH1,ADGRL3,FAM69C,CAMK2A,VXN,CELF3,KCNK10,MAEL,PAX6,PCDH8,CDH8,LGI1,PDE1C,IGFN1,FNDC5,HAPLN2,ST8SIA5,FLRT1,COL9A2,PACSIN1,POU3F2,TENM4,KIAA1755,CALY,SLC45A1,MAPK10,HES5,DPYSL5,ZNF385B,STMN4,KCNA1,OLFM3,CDH20,PTPRD,PTPRO,KCNJ4,CCDC3,TMEM255A,RFX4,FAM135B,RLBP1,SLC4A10,ELAVL3,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.70E-13 1.20E-09 4.22E-12 3.79E-11 84 979 "EPS8,APC2,EMID1,ACTN2,MEG3,IL17D,NDRG2,ADCY2,SLITRK1,CHST15,LRRTM4,DISP3,MOBP,SFPQ,ANK1,DOCK10,NTNG1,CCDC80,ZCCHC17,NLGN1,SLC1A2,SLC6A9,CCDC88A,TAGLN3,ASTN1,B3GAT1,NRG3,JPH4,ARPP21,ADGRB2,NPAS3,NASP,C11orf87,NFIA,RHBDL3,PCDH11X,ZNF638,C1QC,SEMA4A,ROBO3,UNC5D,ADGRL3,DIRAS1,NRGN,CECR2,VSTM2A,PSD3,MFSD2A,CDK11B,REPS2,PCDH9,CDH8,PDE1A,ADGRG1,CA14,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,PRRX1,NXPH1,CRLS1,FEZ1,PLCH2,DZIP3,FMN2,NOS1AP,BRINP3,TOX,SPIRE1,PSMD13,JAKMIP2,PMEPA1,CADM2,LRP8,CCDC3,PCDH15,DLG2,DTNA,SYT15,VWA5A,EPB41,EPB41L1" Coexpression Atlas Arv_EB-LF_2500_K4 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 2.89E-13 1.29E-09 4.51E-12 4.05E-11 41 299 "SYNDIG1,ADGRV1,FABP7,ERMN,NLGN4X,FGF1,FOXG1,PDZD4,SLITRK3,SCG3,CSPG5,SLN,B3GAT1,TMEM151A,DKK3,NMNAT2,GFAP,NPPA,BRSK2,GRIA4,CHGA,SEMA5B,CELF5,FAT3,BTBD17,KCNT2,RIMS4,KIAA1755,PLD5,BRINP3,RIMS3,SHD,KCNA6,KCND3,PTPRZ1,KCNQ2,FAM57B,LINC00599,BSCL2,C2orf80,SEZ6" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_250 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_250 FaceBase_ST1 3.00E-13 1.33E-09 4.66E-12 4.18E-11 34 211 "TTYH1,FABP7,LINC00461,FOXG1,MT3,ASCL1,SCG3,TAGLN3,TTC9B,NPAS3,SPART,FGF17,NFIA,GPM6A,GPM6B,TCF12,INA,ADGRG1,JAM2,GDAP1L1,SPATA6,ACBD5,CRMP1,NKAIN4,FEZ1,MAPK10,HES5,TUBB2B,JAKMIP2,SHD,OLIG1,LMO1,ELAVL3,OLIG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.67E-13 1.63E-09 5.68E-12 5.10E-11 21 78 "MEG3,RTN1,SCN3A,LINC00461,ANK3,SORBS1,NSG2,SCN3B,MYT1L,DNER,NCAM1,BRSK2,GRIA2,INA,NRXN1,UBTF,VCAN,KIAA0408,NTM,RTN4,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.68E-13 1.64E-09 5.68E-12 5.10E-11 19 62 "RTN1,ANK3,NSG2,SNAP25,SCN3B,NCAM1,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,CELF3,DCLK1,NRXN1,CELF5,CEP170,STMN4,RALGDS,ELAVL3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.13E-13 1.84E-09 6.35E-12 5.70E-11 72 778 "ACER3,LGR4,MEG3,EYA1,NDRG2,ADCY2,ADCYAP1R1,FABP7,PNMA8B,GRAMD1B,TUBB4A,SOX6,FOXM1,RASA3,NTNG1,GPAM,LRRC4C,LRRC55,PKNOX2,SORCS3,TMEM108,PALLD,ZCCHC24,NEK6,SPART,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6A,GPM6B,CACNB2,ZEB1,DDR2,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,REPS2,TNS1,PCDH9,DCLK1,LGI1,PDE1A,HPSE2,TMEFF2,ANLN,FADS2,PRRX1,FAT3,SNCAIP,TENM4,MICAL2,ATRNL1,VCAN,MASP1,SYTL2,LRRTM3,PTCH1,PMEPA1,PTPRD,KCND3,SV2A,SRGAP3,TMEM255A,ABCC9,CACNG7,RAVER2,EPB41L2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500 FaceBase_RNAseq 4.45E-13 1.98E-09 6.81E-12 6.11E-11 54 489 "APC2,EMID1,ACTN2,NDRG2,ADCY2,CHST15,LRRTM4,DOCK10,NTNG1,CCDC80,NLGN1,SLC1A2,SLC6A9,ASTN1,NRG3,SOX10,JPH4,ARPP21,ADGRB2,NPAS3,NFIA,RHBDL3,PCDH11X,C1QC,SEMA4A,UNC5D,ADGRL3,CECR2,VSTM2A,PSD3,MFSD2A,REPS2,PCDH9,CDH8,PDE1A,KIAA1549L,NRXN1,SEMA5B,NEGR1,FLRT1,NXPH1,FEZ1,FMN2,BRINP3,TOX,PMEPA1,CADM2,LRP8,CCDC3,PCDH15,DLG2,DTNA,VWA5A,EPB41L1" Coexpression Atlas PCBC_DE_blastocyst_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_1000 PCBC 5.20E-13 2.31E-09 7.95E-12 7.13E-11 84 991 "ACHE,CDHR1,TMEM74,CNTNAP3,ADGRV1,CSMD2,ADCY2,RXRG,GALNT13,FABP7,SORCS1,ERMN,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,GAS7,SLC7A14,SLC1A6,DACH2,SCG3,DDX25,B3GAT1,SOX10,SALL3,LHFPL4,NFASC,RCOR2,FGF17,SYT4,GNG4,NODAL,UNC5D,KLHL4,GPM6A,GPM6B,CECR2,CCKBR,LEFTY2,IGSF21,C1orf94,CDH10,DCLK1,SEZ6L,CA14,ANO5,CHGA,DLGAP3,GDAP1L1,CAMKV,SEMA5B,A2ML1,CELF5,PACSIN1,FAT3,ATCAY,ETNPPL,TENM4,KCNT2,ATRNL1,NCAN,RIMS4,FMN2,RAB39A,IGSF1,RIMS3,ANKS1B,TUBB2B,CADM2,SHD,PLPPR4,KCNQ2,NKAIN1,HS3ST4,SLC25A48,CALN1,DPP6,RET,ST8SIA3,FGFBP3,SLC4A10,C2orf80" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.28E-13 2.35E-09 8.03E-12 7.21E-11 23 97 "EYA1,RTN1,ADCYAP1R1,FABP7,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,GNG3,INA,CELF3,TMEFF2,GDAP1L1,CRMP1,MAPK10,STMN4,PTPRZ1,DLG2,L1CAM,RET,ATL1,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.51E-13 2.45E-09 8.35E-12 7.50E-11 49 417 "MAPT,RTN1,SORCS1,SCN3A,SGIP1,ANK3,APC,NTNG1,DACH2,ASCL1,SNAP25,DKK3,SCN3B,DNER,NPAS3,C11orf87,GFRA1,NFIA,PCDH11X,CAMSAP2,ADGRL3,GRIA1,INA,CDH10,RBFOX2,PIRT,TMEFF2,DUSP26,PRRX1,TENM4,VCAN,FMN2,MAPK8,MAPK10,TUBB2B,JAKMIP2,STMN4,PTPRO,NTM,ARNT2,KCNK2,KCNMA1,KCNQ2,KIF2A,HS3ST4,CALN1,NUP214,RET,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 5.63E-13 2.50E-09 8.51E-12 7.64E-11 41 305 "RTN1,SCN3A,ANK3,CCDC88A,NSG2,SCG3,B3GAT1,SNAP25,DKK3,SCN3B,NMNAT2,FXYD6,NCAM1,SEPT3,ARHGEF7,SYT4,GNAS,GNG3,GNG4,GPM6A,GRIA2,INA,CELF3,PCDH9,DCLK1,RBFOX2,NRXN1,NEGR1,CELF5,ATCAY,CRMP1,TUBB2B,DNAJC6,CEP170,STMN4,KCNJ4,RALGDS,RTN4,CBLN2,ELAVL3,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 6.59E-13 2.93E-09 9.93E-12 8.91E-11 49 419 "TTYH1,APC2,MBP,ADGRV1,ATAT1,RTN1,SLITRK1,FABP7,GRAMD1B,LINC00461,FOXG1,NSG2,ASCL1,ARFGAP1,TAGLN3,SNAP25,ATP2B2,NPAS3,PCDH11X,DCLK2,DDHD2,CAMTA1,GPM6A,GPM6B,ACSL6,DIRAS1,HAP1,GRIK2,MFSD2A,GUCY1A2,CELF3,DCLK1,ADGRG1,GDAP1L1,NRXN2,ATCAY,ACBD5,CRMP1,NCAN,MAPK10,HES5,PROX1,DPYSL5,HP1BP3,STMN4,SRGAP3,PARP11,ELAVL3,OLIG2" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K5 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 6.89E-13 3.06E-09 1.04E-11 9.29E-11 33 205 "ADGRV1,RTKN,RTN1,SLITRK1,FABP7,FOXM1,DLL3,AHCYL1,FGF17,WWC1,WSCD1,ACSL6,GPR19,HAP1,GRIK2,GRIK3,CELF3,ADGRG1,NLGN3,NRXN2,TJP2,CELF5,ATCAY,CRMP1,NCAN,MAPK10,HES5,NOS1AP,PROX1,DPYSL5,ELMO1,SRGAP3,DTNA" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.00E-13 3.11E-09 1.05E-11 9.40E-11 20 72 "RTN1,ANK3,NSG2,SNAP25,FYN,SCN3B,KIF21B,JPH4,SEPT3,SYT4,INA,CELF3,PCDH9,NEGR1,CELF5,FAT3,TOX,KIAA0513,ELAVL3,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500 FaceBase_RNAseq 7.25E-13 3.22E-09 1.08E-11 9.70E-11 54 495 "MBP,ADGRV1,EYA1,F3,RTN1,TUBB4A,LINC00461,FOXG1,ANK3,SHTN1,ASCL1,SCG3,SNAP25,ATP1A3,PHYHIPL,ILDR2,GAD2,STARD10,FGF17,PCDH11X,GNG3,WWC1,WSCD1,GPM6A,HAP1,CECR2,GRIK2,MFSD2A,INA,CELF3,PAX6,TPD52,ADGRG1,CA14,GDAP1L1,CADM1,KIAA1549L,TJP2,NECAB2,PLCH2,CTNND2,MAPK10,HES5,DPYSL5,STMN4,KCNK1,NAV2,SUSD4,DTNA,RAVER2,ELAVL3,ELAVL4,OLIG2,EPB41" Coexpression Atlas Arv_SC-HD_500_K3 AravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 7.54E-13 3.35E-09 1.12E-11 1.01E-10 38 268 "RIMKLA,ADGRV1,FABP7,NLGN4X,PDZD4,PPM1E,SLC1A6,SCG3,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,PCDH11X,SYT6,GRIA4,GRM3,ZDHHC22,IGSF21,C1orf94,CHGA,GDAP1L1,CAMKV,CELF5,ATCAY,BTBD17,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,FGFBP3,LINC00599,SEZ6" Coexpression Atlas PCBC_DE_500 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 8.52E-13 3.78E-09 1.26E-11 1.13E-10 54 497 "TMEM74,ADGRV1,ADCY2,RXRG,FABP7,SORCS1,ERMN,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,SLC7A14,SLC1A6,SCG3,DDX25,B3GAT1,SALL3,LHFPL4,FGF17,SYT4,NODAL,KLHL4,GPM6A,CECR2,CCKBR,LEFTY2,C1orf94,SEZ6L,LGI1,CA14,CHGA,GDAP1L1,SEMA5B,PACSIN1,FAT3,ETNPPL,TENM4,KCNT2,ATRNL1,NCAN,RIMS4,FMN2,RAB39A,RIMS3,ANKS1B,TUBB2B,CADM2,KCNQ2,HS3ST4,SLC25A48,CALN1,RET" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K4 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 8.68E-13 3.86E-09 1.28E-11 1.15E-10 22 90 "TTYH1,APC2,ADGRV1,SHTN1,NSG2,DLL3,ATP2B2,SOX5,SEPT3,DIRAS1,HAP1,GRIK2,CELF3,TUB,POU3F4,NCAN,HES5,DPYSL5,SHD,DTNA,ELAVL3,OLIG2" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2 Gudmap RNAseq 1.22E-12 5.40E-09 1.79E-11 1.61E-10 95 1209 "TTYH1,EPS8,SERPINA3,ACER3,RIMKLA,ACLY,MEG3,WAC,FABP7,SORCS1,GRAMD1B,SNX30,LRRTM4,SEMA6C,SGIP1,CDC42BPA,CNIH2,PKP4,GAS7,CACHD1,NLGN1,ST8SIA1,CLSTN1,ZNF365,KIAA1614,SLC6A9,CADPS,ASTN1,TMEM151A,NRG3,PALLD,DKK3,MYBPC1,TNIK,ADAM15,ADGRB2,NCAM1,COLGALT2,INKA2,NELL1,NFIA,GNG3,ADGRL3,CACNA1A,GPM6A,CACNB2,GPR19,TCF12,AZIN2,DDR2,BRSK2,PSD3,GRIA4,USP2,CDK11B,DCLK1,TPM4,JAM2,NLGN3,KIAA1549L,NRXN1,SEMA5B,NEGR1,CPT1C,FTO,PRRX1,SLC36A4,IFFO1,FAT3,SNCAIP,TENM4,NKAIN4,KCNT2,FEZ1,VCAN,BRINP3,TOX,ANKS1B,TUBB2B,DNAJC6,ELMO1,LRP8,RGMA,PTPRD,KCNA6,PTPRE,PTPRZ1,ATN1,BEND5,CACNG7,PIANP,EFNA3,VWA5A,ELAVL4,PLEKHO1" Coexpression Atlas BM Top 100 - occipital lobe BM Top 100 - occipital lobe Body Map 1.23E-12 5.48E-09 1.81E-11 1.62E-10 20 74 "ERMN,MOBP,FOXG1,SLC1A2,RPH3A,SNAP25,ATP2B2,ARPP21,C11orf87,GPM6A,NRGN,VSTM2A,GRIA2,OPCML,CABP1,CELF5,RIMS3,KCNQ2,ELAVL4,C2orf80" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500 FaceBase_RNAseq 1.53E-12 6.81E-09 2.24E-11 2.01E-10 53 489 "ADGRV1,IL17D,RTN1,SLITRK1,ERMN,TUBB4A,LRRTM4,FHL1,MOBP,FOXG1,SHTN1,TMEM108,PHYHIPL,ILDR2,JPH4,SALL3,NASP,LMO3,AJAP1,ROBO3,GNG3,WWC1,WSCD1,ACSL6,TCF7L2,HAP1,CECR2,GRIK2,INA,CELF3,PAX6,PDE1A,PRMT8,CA14,CADM1,NRXN2,NECAB2,ATCAY,CRMP1,NCAN,MAPK10,HES5,ZBTB16,DPYSL5,CA10,JAKMIP2,CDH20,PTPRZ1,KCNK1,PCDH15,DTNA,ST8SIA3,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.63E-12 7.26E-09 2.38E-11 2.14E-10 15 38 "TTYH1,NDRG2,FABP7,LINC00461,C1orf61,BCAN,ATP1A2,NFIA,GPM6B,SCRG1,PMP2,NCAN,HES5,PTPRZ1,FGFBP3" Coexpression Atlas BM Top 100 - putamen BM Top 100 - putamen Body Map 2.13E-12 9.47E-09 3.09E-11 2.78E-10 20 76 "ERMN,SCN4B,MOBP,FOXG1,SLC1A2,NSG2,GAD2,ARPP21,NCDN,CACNA1E,NRGN,GPR88,PTPN5,FBXL16,HPCA,CELF5,PLPPR4,KCNJ4,KCNQ2,ST8SIA3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.28E-12 1.01E-08 3.30E-11 2.97E-10 30 178 "EYA1,RTN1,SCN3A,SGIP1,ST8SIA1,SLC7A14,DACH2,CADPS,ASTN1,SNAP25,SCN3B,SOX5,DNER,NAP1L2,NPAS3,C11orf87,GFRA1,NFIA,PCDH11X,INA,CDH10,RBFOX2,CNTN1,PRRX1,FAT3,VCAN,MAPK10,DNAJC6,RET,ELAVL4" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.32E-12 1.03E-08 3.35E-11 3.01E-10 70 772 "SYNDIG1,IL17D,MRVI1,NDRG2,ADARB2,ADCY2,SORCS1,SCN3A,KIAA1109,FHL1,SGIP1,SH3GL2,APC,NTNG1,CCDC80,SORBS1,DACH2,CADPS,SCMH1,GPR153,ASPH,SORCS3,DKK3,TNIK,KIF1B,NPAS3,NCAM1,LMO3,CLASP2,SMOC1,NFIA,PCDH11X,ZNF638,CAMSAP2,PRUNE2,GPM6B,VWC2,TCF12,GRIA4,ADAMTS8,ZFP91,PCDH9,RBFOX2,PDE1C,TMEFF2,KIAA1549L,NEGR1,NMT2,CNTN1,MICAL1,PRRX1,CNRIP1,ATRNL1,VCAN,RBPJ,PRKAB2,DZIP3,FMN2,PKN2,IGSF1,PSD,KCND3,RABGAP1L,KCNK2,KCNMA1,KIF2A,PARP11,GOPC,FAM13C,EPB41L2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_100 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_100 FaceBase_ST1 2.35E-12 1.04E-08 3.37E-11 3.03E-10 19 68 "TTYH1,FABP7,LINC00461,FOXG1,MT3,ASCL1,TTC9B,NPAS3,FGF17,NFIA,JAM2,GDAP1L1,NKAIN4,FEZ1,HES5,SHD,OLIG1,LMO1,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.57E-12 1.14E-08 3.68E-11 3.30E-10 15 39 "MEG3,RTN1,SCN3A,ANK3,NSG2,SCN3B,MYT1L,DNER,NCAM1,GRIA2,INA,NRXN1,KIAA0408,NTM,ELAVL4" Coexpression Atlas ratio_SC_vs_ECTO_1000_K1 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 2.83E-12 1.26E-08 4.05E-11 3.64E-10 55 528 "RIMKLA,ADCY2,ADCYAP1R1,RYR1,NLGN4X,HPCAL4,PDZD4,BCAN,SHANK2,SCG3,CSPG5,SNCB,MEGF11,JPH4,LHFPL4,SEPT3,AJAP1,RHBDL3,GNG4,KLHL4,GPM6B,TMEM151B,SYT6,GRIN1,ADAMTS8,TLL2,ZDHHC22,PAH,C1orf94,DCLK1,HRH3,CHGA,GDAP1L1,CAMKV,FAT3,POU3F4,VCAN,RIMS4,IGSF1,LRRTM3,MAGI2,PTPRZ1,NTM,RABGAP1L,KCNQ2,NKAIN1,SLC25A48,CALN1,RET,ST8SIA3,CACNG7,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 3.22E-12 1.43E-08 4.59E-11 4.12E-10 24 115 "MEG3,RTN1,SCN3A,LINC00461,ANK3,SORBS1,NSG2,SCN3B,MYT1L,DNER,NCAM1,BRSK2,GRIA2,INA,PCDH9,CDH8,NRXN1,NRXN2,UBTF,VCAN,KIAA0408,NTM,RTN4,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K1 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.52E-12 1.57E-08 5.00E-11 4.49E-10 39 295 "EMID1,CEND1,ERMN,TUBB4A,FOXRED2,LRRTM4,NTNG1,CCDC80,CLSTN1,PHYHIPL,PALLD,CADM3,ILDR2,JPH4,LMO3,GFRA1,WWC1,WSCD1,CECR2,INA,PAX6,PDE1A,PRMT8,NLGN3,NRXN1,NRXN2,CPT1C,FLRT1,CCDC136,NKAIN4,CTNND2,CA10,SHD,CDH20,KCNN3,CACNG7,PIANP,EFNA3,LRRC23" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_1000 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000 PCBC 3.70E-12 1.64E-08 5.24E-11 4.70E-10 82 992 "RIMKLA,ADCY2,ADCYAP1R1,RYR1,NLGN4X,SCN4B,HPCAL4,PDZD4,BCAN,SHANK2,CGREF1,SCG3,CSPG5,SNCB,ATP1A3,MEGF11,TNIK,JPH4,LHFPL4,ALDH1L1,SEPT3,AJAP1,ACSBG1,RHBDL3,POPDC3,SEMA4A,GNG4,NODAL,KLHL4,GPM6B,DIRAS1,TMEM151B,SYT6,GRIK3,GRIN1,ADAMTS8,MFSD2A,TLL2,ZDHHC22,PAH,C1orf94,DCLK1,HRH3,TPD52,TPM3,TPM4,PDE4B,CHGA,GDAP1L1,CAMKV,NEGR1,PIK3CD,ST8SIA5,PLXNB3,CNTN1,FAT3,POU3F4,VCAN,RIMS4,IGSF1,LRRTM3,PTAFR,PMEPA1,SHD,MAGI2,PTPRZ1,NTM,RABGAP1L,KCNK1,KCNQ2,NKAIN1,SLC25A48,CALN1,RET,ST8SIA3,EEF1A2,CACNG7,FGFBP3,LINC00599,C2orf80,RASGRP2,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.19E-12 1.86E-08 5.91E-11 5.30E-10 31 194 "EYA1,RTN1,FABP7,TUBB4A,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,GFRA1,C1QC,GNG3,B4GALNT4,INA,CELF3,ACOT7,HPSE2,TMEFF2,GDAP1L1,PRRX1,FAT3,CRMP1,NKAIN4,FEZ1,MAPK10,MASP1,STMN4,TMEM255A,L1CAM,RET,CACNG7" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.32E-12 1.92E-08 6.07E-11 5.45E-10 18 62 "EYA1,FABP7,SGIP1,ANK2,CADPS,SCG3,SNAP25,SCN3B,GRIA2,GRIA4,INA,PCDH9,CADM1,NRXN1,JAKMIP2,PTPRZ1,DLG2,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 4.55E-12 2.02E-08 6.37E-11 5.72E-10 69 766 "TTYH1,MAP6,MEG3,ADGRV1,ADD3,FABP7,C1orf61,SFPQ,PPFIA1,CCDC80,LRRC4C,ARHGAP5,CADPS,ASCL1,SMARCE1,CCDC181,SOX1,ILDR2,NMNAT2,NKX6-2,SALL3,NASP,SPART,LMO3,RND1,ARHGEF7,SYT4,NKX2-2,WWC1,GPM6B,ZEB1,TCF12,NRDC,NUDT21,VXN,PSD3,GRM3,PCDH8,SEZ6L,LGI1,LINC01102,HMGB1,SCRG1,JAM2,NRXN1,ANLN,NSD2,FAT3,NXPH1,BTBD17,POU3F2,SF1,TENM4,NCAN,CTNND2,HES5,TOX,PTCH1,PMEPA1,RGMA,MAGI2,C1orf109,PTPRZ1,PANTR1,RALGDS,DTNA,RFX4,FGFBP3,EN2" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 5.47E-12 2.43E-08 7.64E-11 6.86E-10 19 71 "ADGRV1,RTN1,SLITRK1,FABP7,AHCYL1,FGF17,WSCD1,ACSL6,HAP1,GRIK3,INA,CELF3,ADGRG1,POU3F4,NCAN,MAPK10,HES5,PROX1,DPYSL5" Coexpression Atlas PCBC_ECTO_blastocyst_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 5.59E-12 2.49E-08 7.79E-11 6.99E-10 52 490 "MAP6,ADGRV1,FABP7,ADORA1,SLC30A10,SLC1A6,BCO1,ASCL1,SCG3,ASTN1,B3GAT1,PHYHIPL,SOX10,ILDR2,NMNAT2,COLGALT2,STOX1,NELL1,NHLH1,UNC5D,CNTN2,GPM6A,CAMK2A,GRIA4,CELF3,KCNK10,PAX6,IGSF21,CDH8,LGI1,CA14,TMEFF2,CELF5,COL9A2,NECAB2,POU3F2,NKAIN4,KCNT2,PLD5,HES5,RIMS3,DPYSL5,ZNF385B,CADM2,STMN4,KCNA1,OLFM3,PTPRD,DPP6,RFX4,RLBP1,LMO1" Coexpression Atlas adrenal gland adrenal gland Human Protein Atlas 6.96E-12 3.09E-08 9.67E-11 8.68E-10 35 248 "ADGRV1,FAM43B,GALNT13,GRAMD1B,TUBB4A,PPM1E,CADPS,BRINP2,ASTN1,ADGRA1,DNER,SYT4,LUZP2,KLHL4,ANO4,PRLHR,VSTM2A,CELF3,PCSK2,PIRT,DNAJC12,ST8SIA5,FLRT1,NXPH1,CALY,KCNA4,KCNK2,PCDH15,NKAIN1,CALN1,L1CAM,RGS7,FAM135B,GPR61,ELAVL4" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_500 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_500 FaceBase_ST1 7.14E-12 3.17E-08 9.89E-11 8.88E-10 43 358 "DPF1,TTYH1,MDM4,FABP7,ERMN,LINC00461,FOXG1,APBA2,MT3,ASCL1,SCG3,CSPG5,CCDC181,PHYHIPL,GAD2,TTC9B,NPAS3,ACSBG1,NFIA,GPM6A,GPM6B,GPR19,INA,PAX6,ADGRG1,JAM2,GDAP1L1,FAM181B,C11orf49,NKAIN4,FEZ1,HES5,TOX,TUBB2B,JAKMIP2,PMEPA1,STMN4,PTPRZ1,SRGAP3,PARP11,ATL1,LMO1,ELAVL3" Coexpression Atlas Arv_SC-LF_500_K3 AravindRamakr_StemCell-LF_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 7.36E-12 3.27E-08 1.02E-10 9.11E-10 42 344 "ADGRV1,ADCY2,FABP7,NLGN4X,PDZD4,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,PCDH11X,GPM6B,TMEM151B,SYT6,GRIA4,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,GDAP1L1,CAMKV,CELF5,BTBD17,POU3F4,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,DPP6,FGFBP3,LINC00599,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 7.63E-12 3.39E-08 1.05E-10 9.40E-10 17 56 "MAP6,RTN1,SCN3A,ANK3,NSG2,SCG3,TAGLN3,DNER,NCAM1,SYT4,GNG3,CNTN2,GPM6A,INA,SLC17A6,L1CAM,ELAVL3" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.64E-12 3.39E-08 1.05E-10 9.40E-10 75 880 "TTYH1,EPS8,ABAT,ACLY,SYT9,MEG3,EYA1,F3,FABP7,PNMA8B,GRAMD1B,ADORA1,BCAR3,FHL1,SOX6,SEMA6C,USP28,SH3GL2,DOCK10,GAS7,DGKD,ST8SIA1,SHTN1,KIAA1614,CADPS,PDE8B,CSPG5,FYN,TNIK,SOX10,FXYD6,SMOC1,NELL1,ADHFE1,PHLDB1,ACSBG1,NFIA,SEMA4A,GPM6B,DDR1,NRDC,VXN,MFSD2A,DAAM2,PADI2,TPD52,FNDC5,ADGRG1,JAM2,SERPINE2,SEMA5B,NMT2,FADS2,CP,FEZ2,MICAL2,VCAN,DOCK7,ARHGEF4,MASP1,TOX,TUBB2B,LRRTM3,PTCH1,JAKMIP2,ELMO1,PTPRD,PTPRE,PLPPR4,KCNH1,SRGAP3,NAV2,GNE,DTNA,SIDT2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_250 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_250 FaceBase_ST1 1.04E-11 4.62E-08 1.42E-10 1.28E-09 28 165 "TTYH1,CEND1,KLHL32,FABP7,LINC00461,C1QTNF4,FOXG1,MT3,ASCL1,TAGLN3,GAD2,TTC9B,NPAS3,FGF17,NFIA,CHGA,JAM2,GDAP1L1,NKAIN4,FEZ1,HES5,PMEPA1,SHD,STMN4,OLIG1,LMO1,ELAVL3,OLIG2" Coexpression Atlas PCBC_ratio_SC_vs_PulmonMicrovasc_cfr-2X-p05 Pluripotent Stem Cells_vs_Pulmonary Microvascular-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.04E-11 4.63E-08 1.42E-10 1.28E-09 117 1688 "TTYH1,LGR4,ARID1A,RTKN,NDRG2,ADCY2,CDC7,FABP7,TUBB4A,NLGN4X,DRAXIN,SEMA6A,USP28,CNIH2,SESN3,TACC2,SORBS1,CACHD1,SLC6A9,ARHGAP5,SCG3,CAPRIN2,DDX25,ALDH4A1,ATP1A2,ATP1A3,GABBR1,JPH4,MIR4697HG,ADGRB2,NAP1L2,FXYD6,RAP1GAP2,NASP,ZNF302,RCOR2,RND1,SEPT3,RHBDL3,ASTN2,GNG4,UNC5D,WWC1,WSCD1,GPM6B,DDR1,TCF7L2,B4GALNT4,GPR19,DIRAS1,PTBP2,EML4,CECR2,SYT6,MFSD2A,INA,TMEM9,ZDHHC22,DCLK1,MAGI1,CA14,PLEKHB1,TUB,ZBED5,SERPINE2,CADM1,CAMKV,SEMA5B,PIK3CD,CPT1C,CCDC136,MICAL1,BTF3L4,ATCAY,CRMP1,FEZ1,VCAN,RIMS4,RBPJ,PRKAB2,DZIP3,PRKCZ,USP54,IGSF1,FAM131B,ECE2,RIMS3,TUBB2B,JAKMIP2,RGMA,PTPRD,PTPRZ1,SV2A,RABGAP1L,KCNK1,SNX27,KCNQ2,DLG3,NKAIN1,FAM57B,L1CAM,ABCC9,JMJD1C,ARHGEF10L,EEF1A2,VANGL2,SEC61A2,CACNG7,RBM12,RPRD1A,FGFBP3,ARHGAP12,RAVER2,LINC00599,BSCL2,EPB41,EPB41L1" Coexpression Atlas PCBC_ratio_EB_vs_SC_500 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500 PCBC 1.11E-11 4.94E-08 1.51E-10 1.36E-09 52 499 "SERPINA3,C1orf194,WLS,RXRG,AGT,SCN3A,LINC00461,SOX6,CCDC80,NSG2,ASCL1,SLIT1,SNAP25,PHYHIPL,ILDR2,ENKUR,NCAM1,NELL1,NHLH1,DCLK2,MYRF,CDK5R2,CNTN2,ZEB1,DDR2,GRIA2,TF,OLR1,GUCY1A1,CELF3,PAX6,LGI1,PDE1A,FNDC5,ADGRG1,SCRG1,FAM181B,PRRX1,POU3F2,CSF3R,KIAA1755,PLPP4,HES5,ZBTB16,PTHLH,STMN4,CCDC3,SLC17A6,RFX4,SLC39A12,ELAVL3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.22E-11 5.42E-08 1.65E-10 1.48E-09 19 74 "MEG3,RTN1,SCN3A,SYBU,TAGLN3,NKX6-2,NCAM1,SEPT3,SYT4,GPM6A,GRIA2,INA,PCDH9,GDAP1L1,NEGR1,PLPPR1,PANTR1,ELAVL3,ELAVL4" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.22E-11 5.44E-08 1.65E-10 1.48E-09 24 122 "TTYH1,APC2,ADGRV1,FOXM1,SHTN1,NSG2,DLL3,ATP2B2,SOX5,SEPT3,DIRAS1,HAP1,GRIK2,CELF3,TUB,POU3F4,NCAN,HES5,DPYSL5,SHD,DTNA,ELAVL3,OLIG2,PLEKHO1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 1.84E-11 8.19E-08 2.48E-10 2.23E-09 51 490 "ACTN2,ADGRV1,ERMN,HPCAL4,MOBP,SH3GL2,GAS7,SLC1A2,BCO1,CCDC88A,SLCO1A2,DLL3,ADGRA1,ATP1A3,ATP2B2,ARPP21,TTLL9,C11orf87,ACSBG1,CLEC9A,CAMK2A,GRIA1,GRIK2,TMEM25,LEFTY2,INA,CELF3,REPS2,HPSE2,GDAP1L1,NRXN2,ATCAY,NXPH1,MICAL2,PLCH2,IGSF1,MAPK10,HES5,MASP1,ZNF385B,ITGAV,CADM2,STMN4,KCNA6,PCDH15,DLG2,ST8SIA3,ELAVL3,PRRT4,RASGRP2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.95E-11 8.66E-08 2.62E-10 2.35E-09 17 59 "MEG3,RTN1,FABP7,SCN3A,C1orf61,NSG2,ASCL1,MYT1L,NCAM1,GPM6A,TCF12,GRIA2,GRIA4,INA,NRXN2,ELAVL4,EN2" Coexpression Atlas PCBC_ratio_ECTO_vs_DE_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.02E-11 8.95E-08 2.70E-10 2.42E-09 86 1100 "TTYH1,EMID1,TMEM74,CNTNAP3,LGR4,PAQR6,ATAT1,WLS,FABP7,TESK2,PLA2G6,FHL1,ASRGL1,APBA2,APBB1,SESN3,CCDC80,DGKD,TACC2,NLGN1,ST3GAL3,NBPF1,BCO1,PKNOX2,SCMH1,GPR153,ASTN1,ATP1A2,PALLD,WDTC1,SOX1,CADM3,ILDR2,ADAM15,FXYD6,COLGALT2,STOX1,SMOC1,GPR162,RGL1,PHLDB1,RND1,VAMP1,DDHD2,UNC5D,ADGRL3,WSCD1,GPR19,PCDHGA3,NUMA1,CROCCP2,PTPN5,TGFBR3,KCNK10,PAX6,IGSF21,CDH8,LGI1,CIART,FNDC5,ADGRG1,CA14,TUB,NLGN3,CPT1C,CCDC136,SLC25A27,MICAL1,ATCAY,POU3F2,NKAIN4,ARHGEF4,CTNND2,HES5,FAM131B,ZBTB16,DPYSL5,ZNF385B,RGMA,OLFM3,PTPRD,SV2A,ARNT2,CAB39L,PIANP,BAALC" Coexpression Atlas PCBC_ratio_SC_vs_DE_cfr-2X-p05 Pluripotent Stem Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.18E-11 9.68E-08 2.91E-10 2.61E-09 46 415 "TTYH1,LGR4,FABP7,NLGN4X,FHL1,SESN3,TACC2,DDX25,ATP1A2,ATP1A3,JPH4,MIR4697HG,ADAM15,NAP1L2,RND1,SEPT3,RHBDL3,GNG4,UNC5D,WSCD1,GPM6B,GPR19,SYT6,MFSD2A,AIFM1,ZDHHC22,CAMKV,PIK3CD,CPT1C,TJP2,ATCAY,VCAN,RIMS4,IGSF1,FAM131B,ECE2,TOX,JAKMIP2,PTPRZ1,RABGAP1L,NKAIN1,FAM57B,ARHGEF10L,CACNG7,FGFBP3,LINC00599" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE76381_iPSMoleculeCountsPMLog2 2.28E-11 1.01E-07 3.04E-10 2.73E-09 21 95 "RTN1,ANK3,NSG2,B3GAT1,SNAP25,SCN3B,NCAM1,SEPT3,ARHGEF7,SYT4,GNG3,GPM6A,CELF3,DCLK1,SCRG1,NRXN1,CELF5,CEP170,STMN4,RALGDS,ELAVL3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.31E-11 1.03E-07 3.07E-10 2.75E-09 69 794 "EPS8,ACER3,LGR4,MEG3,EYA1,KLHL32,ADCYAP1R1,FABP7,PNMA8B,GRAMD1B,TUBB4A,SOX6,FOXM1,RASA3,DOCK10,NTNG1,GAS7,GPAM,ST8SIA1,PKNOX2,CADPS,DDX25,SORCS3,TMEM108,FYN,PALLD,TNIK,ZCCHC24,NEK6,SPART,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,PSRC1,ADGRL3,GPM6A,GPM6B,ZEB1,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,REPS2,PCDH9,CDH10,DCLK1,PDE1A,HPSE2,TMEFF2,SERPINE2,ANLN,FAT3,TENM4,MICAL2,VCAN,MASP1,LRRTM3,PTCH1,PTPRD,KCND3,KCNH1,SV2A,SRGAP3,TMEM255A,DTNA,RAVER2" Coexpression Atlas geo_heart_2500_K5 geo_heart_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 2.35E-11 1.04E-07 3.11E-10 2.79E-09 57 590 "DUSP27,SYNDIG1,RXRG,HHATL,LCNL1,HOGA1,FGF1,FHL1,MOG,SEMA6C,PI16,KIAA1614,SLC1A7,PKNOX2,MT3,NSG2,PDE8B,SLN,TMEM108,IGSF9B,DKK3,MYBPC1,NMNAT2,IDI2-AS1,NFASC,GFAP,ABCC8,PCDH11X,SYT4,POPDC3,GPM6A,FAM69C,ACSL6,VWC2,NPPA,GPR17,DIRAS1,VXN,USP2,MAEL,FNDC5,SCRG1,ANO5,JAM2,ST8SIA5,PACSIN1,KIAA1755,PROX1,ZNF385B,SHD,CDH20,KCND3,KCNJ4,RABGAP1L,KCNK1,DTNA,CRTAC1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.59E-11 1.15E-07 3.41E-10 3.06E-09 25 137 "ADCYAP1R1,FABP7,SOX6,PPM1E,SLC1A2,SCG3,B3GAT1,PHYHIPL,ILDR2,KIF1B,NPAS3,GNG3,HAP1,CDH8,JAM2,NRXN2,SEMA5B,FAM181B,CTNND2,TUBB2B,JAKMIP2,PTPRZ1,SRGAP3,RFX4,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.89E-11 1.29E-07 3.80E-10 3.41E-09 69 798 "ABAT,LGR4,MEG3,ADCYAP1R1,FABP7,PNMA8B,CHST15,SOX6,RASA3,SESN3,CCDC80,GPAM,CACHD1,LRRC4C,ST8SIA1,SHTN1,PKNOX2,SCMH1,PDE8B,CAPRIN2,MTR,TMEM108,PALLD,MYBPC1,TNIK,ZCCHC24,NEK6,NPAS3,NCAM1,SMOC1,NELL1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6B,CACNB2,ZEB1,TCF12,PSD3,GRIA4,GRIK3,GUCY1A2,GUCY1A1,DAAM2,REPS2,PCDH9,DCLK1,MAGI1,PDE1A,FNDC5,HPSE2,CHRM4,PRRX1,FAT3,SNCAIP,TENM4,ATRNL1,VCAN,PLD5,PMEPA1,MAGI2,SV2A,SRGAP3,NAV2,TMEM255A,ABCC9,RAVER2,EPB41L1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_250 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_250 FaceBase_ST1 3.34E-11 1.48E-07 4.38E-10 3.93E-09 28 173 "FABP7,ERMN,LINC00461,FOXG1,APBA2,MT3,ASCL1,SCG3,GAD2,TTC9B,NPAS3,NFIA,GPM6A,GPR19,INA,PAX6,JAM2,FAM181B,FEZ1,HES5,TOX,TUBB2B,JAKMIP2,PMEPA1,SRGAP3,PARP11,LMO1,ELAVL3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.47E-11 1.54E-07 4.54E-10 4.07E-09 16 53 "MAP6,CSMD3,RTN1,ADCYAP1R1,SLC7A14,NSG2,NCAM1,DCLK1,FEZ1,NRSN1,MAPK10,PROX1,DPYSL5,STMN4,L1CAM,RET" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 3.48E-11 1.55E-07 4.54E-10 4.07E-09 21 97 "RTN1,LINC00461,SOX6,ASCL1,SCG3,B3GAT1,SNAP25,PHYHIPL,GPM6A,GPM6B,HAP1,CDH8,NRXN2,FAM181B,FAT3,POU3F4,CTNND2,PROX1,TUBB2B,PTPRZ1,SRGAP3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.12E-11 1.83E-07 5.33E-10 4.79E-09 15 46 "EYA1,RTN1,FABP7,CADPS,SCG3,SNAP25,SCN3B,GFRA1,INA,TMEFF2,FEZ1,MAPK10,STMN4,L1CAM,RET" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.12E-11 1.83E-07 5.33E-10 4.79E-09 18 70 "MEG3,RTN1,FABP7,SCN3A,ANK3,NSG2,DKK3,MYT1L,NCAM1,LMO3,GPM6A,INA,TUB,KIAA0408,NTM,ELAVL4,EN2,RCAN2" Coexpression Atlas PCBC_MESO-5_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_1000 PCBC 4.13E-11 1.84E-07 5.34E-10 4.79E-09 79 985 "EMID1,TMEM74,SYNDIG1,ADGRV1,CSMD3,RXRG,GALNT13,SORCS1,ERMN,ADORA1,NLGN4X,C1QTNF4,UNC79,C1orf61,PDZD4,SH3GL2,SLC1A6,DACH2,SCG3,DDX25,RCOR3,B3GAT1,ADGRA1,PHYHIPL,SOX10,SALL3,LHFPL4,FGF17,AJAP1,CASTOR3,NODAL,MYRF,KLHL4,GPM6A,NPPA,CECR2,GRIK3,OLR1,CCKBR,PTPN5,LEFTY2,USP2,PAX6,IGSF21,PCDH8,CDH8,SEZ6L,PCSK2,CA14,PLEKHB1,DLGAP3,SEMA5B,A2ML1,CELF5,COL9A2,NECAB2,PACSIN1,ETNPPL,KCNT2,RIMS4,FMN2,RAB39A,PLPP4,ANKS1B,TUBB2B,ZNF385B,CADM2,SHD,RGMA,PTPRD,KCNQ2,HS3ST4,SLC25A48,CALN1,SLC25A18,DSCAM,USH1C,SLC4A10,ELAVL4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.77E-11 2.12E-07 6.14E-10 5.51E-09 16 54 "EYA1,RTN1,FABP7,ANK2,CADPS,SNAP25,SCN3B,NCAM1,INA,DCLK1,CADM1,FEZ1,MAPK10,STMN4,DLG2,L1CAM" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 40 GSE76381_iPSMoleculeCountsPMLog2 4.96E-11 2.21E-07 6.38E-10 5.72E-09 25 141 "MAP6,RTN1,SCN3A,ANK3,APBB1,NBPF1,NSG2,SNAP25,SCN3B,DNER,FXYD6,NCAM1,CLASP2,SYT4,GPM6A,CELF3,CHGA,CRMP1,SLC45A1,CTNND2,KIAA0408,ELMO1,STMN4,CBLN2,ELAVL3" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_100 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_100 PCBC 5.25E-11 2.33E-07 6.70E-10 6.02E-09 21 99 "CEND1,RYR1,SCN4B,PPM1E,ATP1A3,DNER,RHBDL3,TMEM151B,SYT6,GRIA4,FBXL16,ZDHHC22,C1orf94,DCLK1,HRH3,CHGA,CAMKV,CABP1,PHYHIP,FGFBP3,LINC00599" Coexpression Atlas PCBC_ratio_SC_vs_DE_100 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_100 PCBC 5.25E-11 2.33E-07 6.70E-10 6.02E-09 21 99 "CEND1,SCN4B,ACTL6B,HPCAL4,BCAN,LRRC55,ATP1A3,JPH4,ACSBG1,RHBDL3,TMEM151B,TLL2,ZDHHC22,PAH,HRH3,CAMKV,BTBD17,PHYHIP,LINC00599,RASGRP2,SEZ6" Coexpression Atlas PCBC_ratio_SC_vs_DE_1000 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000 PCBC 5.28E-11 2.34E-07 6.72E-10 6.03E-09 79 990 "TTYH1,CEND1,RYR1,SCN4B,ACTL6B,ELMOD1,HPCAL4,SLITRK3,BCAN,LRRC55,CGREF1,TMEM151A,ATP1A2,ATP1A3,KIF21B,JPH4,CPLX2,DNER,LMO3,ALDH1L1,INKA2,RND1,SEPT3,SLCO1C1,ACSBG1,ABCC8,RHBDL3,PCDH11X,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRIN1,TLL2,ZDHHC22,PAH,TNFRSF1B,HRH3,CHGA,CHRNB2,TMEFF2,NLGN3,NRXN2,CAMKV,ST8SIA5,VAV2,CNTN1,CABP1,BTBD17,POU3F4,SNCAIP,NKAIN4,RIMS4,RAB39A,PRKCG,SLC45A1,PSD,TOX,PHYHIP,LRRTM3,JAKMIP2,PARD6A,PTPRO,PTPRZ1,NTM,AK5,KCNMA1,KCNN3,PYGM,SUSD4,ATL1,ARHGEF10L,CACNG7,FGFBP3,LINC00599,RASGRP2,SEZ6,ATP6V1G2-DDX39B" Coexpression Atlas GSM605843_500 "Plasmacytoid, DC.pDC.8-.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 5.90E-11 2.62E-07 7.49E-10 6.72E-09 45 412 "EYA1,LDLRAD3,SNX30,FOXRED2,CHST15,SCN3A,FGR,PDZD4,SELL,ITSN1,PPM1E,GAS7,ST8SIA1,ARHGAP5,CCDC88A,ASPH,ATP1A3,FYN,ZCCHC24,NEK6,GPR162,RGL1,GPM6B,CACNA1E,DDR1,TCF7L2,CLEC9A,CYB561A3,ATP13A2,PADI2,TNS1,TPD52,FADS2,VAV2,P2RY12,PACSIN1,ATRNL1,CTNND2,TUBB2B,SIRPA,PTAFR,LRP8,SRGAP3,RABGAP1L,GNE" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.05E-11 2.69E-07 7.66E-10 6.88E-09 65 741 "ABAT,LGR4,MEG3,ADCY2,FABP7,KIAA1109,RASA3,SESN3,CCDC80,GPAM,LRRC4C,ST8SIA1,SHTN1,PKNOX2,SCMH1,PDE8B,CAPRIN2,MTR,PALLD,TNIK,SOX5,NPAS3,NCAM1,SMOC1,NELL1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6B,CACNB2,TCF12,PSD3,GRIK3,GUCY1A2,GUCY1A1,DAAM2,REPS2,PCDH9,DCLK1,LGI1,MAGI1,PDE1A,FNDC5,ADGRG1,HMGB1,HPSE2,CHRM4,NMT2,PRRX1,FAT3,PPP2R5C,TENM4,ATRNL1,VCAN,PRKACB,PLD5,MAGI2,PTPRD,PTPRO,SRGAP3,RABGAP1L,NAV2,TMEM255A,SSPN" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.50E-11 2.89E-07 8.20E-10 7.36E-09 16 55 "FABP7,SGIP1,ANK2,SCG3,SNAP25,PHYHIPL,NAP1L2,GRIA2,INA,CADM1,NRXN1,JAKMIP2,PTPRZ1,DLG2,RGS7,ELAVL4" Coexpression Atlas ratio_EB_vs_SC_500_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 7.85E-11 3.49E-07 9.87E-10 8.86E-09 30 204 "C1orf194,LINC00461,SOX6,NSG2,ASCL1,SLIT1,SNAP25,PHYHIPL,ILDR2,ENKUR,NELL1,NHLH1,MYRF,CDK5R2,CNTN2,GRIA2,TF,OLR1,CELF3,LGI1,SCRG1,FAM181B,POU3F2,STMN4,CCDC3,SLC17A6,RFX4,SLC39A12,ELAVL3,ELAVL4" Coexpression Atlas PCBC_DE_blastocyst_500 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_500 PCBC 7.93E-11 3.52E-07 9.95E-10 8.93E-09 50 494 "CDHR1,ADGRV1,ADCY2,RXRG,FABP7,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,SLC7A14,SLC1A6,SCG3,DDX25,B3GAT1,SOX10,SALL3,LHFPL4,FGF17,SYT4,NODAL,KLHL4,GPM6A,CECR2,CCKBR,LEFTY2,C1orf94,SEZ6L,CHGA,DLGAP3,GDAP1L1,SEMA5B,PACSIN1,FAT3,TENM4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,ANKS1B,TUBB2B,CADM2,KCNQ2,HS3ST4,SLC25A48,CALN1,DPP6,RET" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500 FaceBase_RNAseq 9.15E-11 4.07E-07 1.14E-09 1.03E-08 50 496 "ADGRV1,RTN1,SLITRK1,FABP7,TUBB4A,FHL1,ZCCHC17,PKNOX2,SCG3,PHYHIPL,ILDR2,AHCYL1,NMNAT2,TTLL9,NASP,FGF17,AJAP1,WWC1,WSCD1,ACSL6,GPR19,HAP1,CECR2,GRIK3,INA,CELF3,PRMT8,ADGRG1,CA14,CADM1,NRXN2,SEMA5B,FLRT1,FAM181B,POU3F4,KCNT2,NCAN,CTNND2,MAPK10,HES5,PROX1,ZBTB16,DPYSL5,JAKMIP2,CDH20,NAV2,ST8SIA3,RFX4,LPAR6,LRRC23" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.16E-11 4.07E-07 1.14E-09 1.03E-08 71 855 "ABAT,PRR5L,CDHR1,EMID1,SYT9,LGR4,MEG3,EYA1,MRVI1,ADCY2,SLC30A10,AMPH,ASRGL1,SGIP1,ANK2,ST8SIA1,RUFY2,MSR1,SLC14A1,DACH2,GPR153,SORCS3,ASTN1,EIF4G3,DKK3,NEK6,KIF1B,ADGRB2,DNER,FXYD6,NASP,NCAM1,C11orf87,SYT4,CAMTA1,ADGRL3,KLHL4,ANO4,TBX15,B4GALNT4,DDR2,VSTM2A,AKNA,GRIA1,GRIA4,GRM3,PCDH8,DCLK1,LGI1,TPD52,PDE1C,TMEFF2,NEGR1,CNTN1,PRRX1,CRMP1,SNCAIP,GON4L,ELMO1,LRP8,KCNA1,PTPRO,NTM,AK5,CCDC3,ARNT2,DNM2,ABCC9,CRTAC1,TTLL7,EFNA3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 9.24E-11 4.10E-07 1.15E-09 1.03E-08 39 328 "KLHL32,FHL1,SOX6,CDC42BPA,PPM1E,NLGN1,MADD,SCG3,ASTN1,B3GAT1,ADGRA1,PHYHIPL,ILDR2,NASP,LMO3,GNG3,CACNA1A,PTBP2,CDK11B,PAX6,PCDH9,CDH8,MAGI1,PRMT8,JAM2,KIAA1549L,NRXN2,SEMA5B,FAM181B,FAT3,FEZ1,FMN2,CTNND2,SPIRE1,TUBB2B,JAKMIP2,PTPRZ1,RFX4,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.07E-10 4.75E-07 1.33E-09 1.19E-08 17 65 "MEG3,RTN1,FABP7,SCN3A,C1orf61,NSG2,ASCL1,MYT1L,NCAM1,GPM6A,GRIA2,GRIA4,INA,NRXN2,L1CAM,ELAVL4,EN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.18E-10 5.24E-07 1.46E-09 1.31E-08 68 806 "PRR5L,MAPT,ACTN2,MEG3,EYA1,IL17D,RTN1,SLITRK1,FABP7,SORCS1,BBOX1,ELMOD1,SLC30A10,FOXG1,SOX6,ANK1,ANK2,BCAS1,MSR1,YPEL4,SLC14A1,SPHKAP,SLN,MTR,SNAP25,SCN3B,MYBPC1,MYH7,ARPP21,DNER,C11orf87,ALDH1L1,ADHFE1,NFIA,GNG4,MMD2,VWC2,GRIA1,GRIA4,GRM3,VWCE,TF,PAH,MAEL,PCDH8,DCLK1,TPM3,NEGR1,CNTN1,PRRX1,IFFO1,CRMP1,IGSF1,NRSN1,MAPK10,MASP1,SPIRE1,DNAJC6,ITIH2,RABGAP1L,TMCC2,KCNK2,FAM13C,ST8SIA3,EFNA3,SH3GLB1,ELAVL4,EPB41" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.18E-10 5.25E-07 1.46E-09 1.31E-08 16 57 "MEG3,RTN1,FABP7,SCN3A,C1orf61,NSG2,ASCL1,MYT1L,NCAM1,GPM6A,GRIA2,GRIA4,INA,NRXN2,ELAVL4,EN2" Coexpression Atlas GSM605840_500 "Plasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 1.58E-10 7.01E-07 1.94E-09 1.74E-08 44 409 "EYA1,LDLRAD3,SNX30,FOXRED2,CHST15,SCN3A,FGR,PDZD4,SELL,ITSN1,PPM1E,GAS7,ST8SIA1,ARHGAP5,CCDC88A,ASPH,ATP1A3,FYN,ZCCHC24,NEK6,GPR162,RGL1,GPM6B,CACNA1E,DDR1,TCF7L2,CLEC9A,CYB561A3,ATP13A2,PADI2,TNS1,TPD52,FADS2,VAV2,P2RY12,PACSIN1,ATRNL1,CTNND2,SIRPA,PTAFR,LRP8,SRGAP3,RABGAP1L,GNE" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.81E-10 8.04E-07 2.22E-09 1.99E-08 18 76 "MAP6,RTN1,SCN3A,ANK3,NBPF1,NSG2,SNAP25,SCN3B,NCAM1,CLASP2,SYT4,GPM6A,CELF3,CHGA,CTNND2,ELMO1,STMN4,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.81E-10 8.04E-07 2.22E-09 1.99E-08 18 76 "MEG3,RTN1,SCN3A,ANK3,NSG2,SCN3B,MYT1L,DNER,NCAM1,GRIA2,INA,PCDH9,CDH8,NRXN1,NRXN2,KIAA0408,NTM,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.22E-10 9.87E-07 2.71E-09 2.43E-08 69 836 "EPS8,PRR5L,ACER3,EYA1,GALNT13,SORCS1,SCN3A,LRRTM4,SFPQ,SGIP1,NTNG1,ZNF365,MIER1,CCDC88A,SLC14A1,DACH2,CADPS,ASPH,ASTN1,SON,ARPP21,SALL3,DNER,NAP1L2,NPAS3,LMO3,NFIA,GLS,GNG4,UNC5D,ADGRL3,TBX15,PTBP2,DDR2,PSD3,GRIA2,ZFP91,PCDH8,CDH10,DCLK1,NLGN3,NEGR1,BTF3L4,PRRX1,FAT3,PPP3CB,VCAN,FMN2,MAPK8,TOX,LRRTM3,DNAJC6,JAKMIP2,LRP8,CEP170,MAGI2,BLOC1S6,KCNA1,KCNA4,PTPRE,PTPRZ1,NTM,KCNK2,TMEM255A,PARP11,GOPC,FAM13C,EFNA3,CBLN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.29E-10 1.02E-06 2.78E-09 2.50E-08 25 151 "EYA1,SORCS1,SCN3A,SGIP1,NTNG1,DACH2,CADPS,ASTN1,NAP1L2,NPAS3,NFIA,ADGRL3,PTBP2,GRIA2,CDH10,DCLK1,NEGR1,PRRX1,FAT3,FMN2,LRRTM3,JAKMIP2,LRP8,KCNK2,EFNA3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K4 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.61E-10 1.16E-06 3.17E-09 2.85E-08 23 129 "APC2,FOXG1,MADD,SORCS3,SNAP25,SEPT3,CACNA1A,CACNB2,HAP1,GRIK2,PAX6,PRMT8,GDAP1L1,NRXN2,CCDC136,CELF5,ATCAY,ATRNL1,IGSF1,SV2A,SRGAP3,ARNT2,L1CAM" Coexpression Atlas Arv_SC-LF_500 AravindRamakr_StemCell-LF_top-relative-expression-ranked_500 PCBC 2.84E-10 1.26E-06 3.43E-09 3.08E-08 49 496 "ADGRV1,ADCY2,FABP7,NLGN4X,C1orf61,PDZD4,SLC1A6,SCG3,CSPG5,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,ACSBG1,PCDH11X,SYT4,NODAL,GPM6A,GPM6B,TMEM151B,SYT6,GRIA4,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,GDAP1L1,CAMKV,A2ML1,CABP1,CELF5,BTBD17,POU3F4,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,DPP6,FGFBP3,LINC00599,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.85E-10 1.26E-06 3.43E-09 3.08E-08 13 37 "MEG3,RTN1,SCN3A,ANK3,NSG2,TAGLN3,SEPT3,INA,PCDH9,CRMP1,STMN4,EEF1A2,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.85E-10 1.26E-06 3.43E-09 3.08E-08 13 37 "MEG3,RTN1,SCN3A,ANK3,NSG2,TAGLN3,SEPT3,INA,PCDH9,CRMP1,STMN4,EEF1A2,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 2.94E-10 1.31E-06 3.53E-09 3.17E-08 21 108 "TTYH1,ADGRV1,SLITRK1,FOXG1,ASRGL1,SHTN1,TAGLN3,DLL3,ATP2B2,WSCD1,ACSL6,DIRAS1,GRIK2,ADGRG1,TUB,CELF5,ATCAY,MAPK10,DPYSL5,DTNA,OLIG2" Coexpression Atlas PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05 MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.95E-10 1.31E-06 3.53E-09 3.17E-08 91 1257 "PRR5L,EMID1,LGR4,ECSIT,LDLRAD3,PLEKHG5,SORCS1,NLGN4X,CHST15,SEMA6A,ANK2,USP28,APBA2,MAGI3,CLSTN1,PKNOX2,CCDC88A,ASCL1,CSPG5,BRINP2,ASTN1,RCOR3,ALDH4A1,ATM,PHYHIPL,DKK3,ILDR2,FXYD6,COLGALT2,GPR162,GFRA1,RCOR2,ADHFE1,NEUROD1,ZNF638,KAZN,DDHD2,ADGRL3,GPM6A,GPM6B,FAM69C,B4GALNT4,TCF12,CECR2,NUMA1,CROCCP2,OPCML,CRB1,LEFTY2,ATG4C,PAX6,LGI1,CIART,FNDC5,CA14,TUB,DUSP26,CPT1C,DNAJC12,FLRT1,CCDC136,CNTN1,SLC25A27,COL9A2,FAT3,CP,TENM4,NKAIN4,RBPJ,ARHGEF4,ZBTB16,TOX,PTCH1,SHD,CDH20,PTPRD,SV2A,SRGAP3,KCNJ4,ARNT2,KCNK1,PYGM,RAD52,RALGDS,FAM13C,BEND5,PIANP,EFNA3,LMO1,FGFBP3,LRRC23" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 2.98E-10 1.32E-06 3.54E-09 3.17E-08 17 69 "RTN1,SEMA6A,ANK3,NLGN1,NSG2,SNAP25,DKK3,SCN3B,KIF21B,SEPT3,SYT4,INA,CELF3,DNAJC12,CELF5,ELAVL3,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 2.98E-10 1.32E-06 3.54E-09 3.17E-08 17 69 "MAP6,RTN1,SCG3,TAGLN3,DLL3,NCAM1,NEUROD1,NHLH1,SYT4,GNG3,CNTN2,INA,FNDC5,SLC17A6,RGS10,ELAVL3,EPB41" Coexpression Atlas BM Top 100 - cerebellum BM Top 100 - cerebellum Body Map 2.98E-10 1.32E-06 3.54E-09 3.17E-08 17 69 "SNAP25,MEGF11,NEUROD1,SYT4,CACNA1A,OPCML,PAX6,PDE1A,CELF5,MICAL2,CA10,KCNA1,KCNC1,KCNQ2,CALN1,LINC00599,EN2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k1 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.37E-10 1.50E-06 3.99E-09 3.59E-08 24 142 "ABAT,MEG3,MRVI1,ST8SIA1,SLC14A1,DACH2,SORCS3,DNER,NCAM1,SYT4,ANO4,DDR2,VSTM2A,GRIA1,GRIA4,GRM3,LGI1,PDE1C,TMEFF2,NEGR1,CNTN1,PRRX1,KCNA1,NTM" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.59E-10 1.60E-06 4.23E-09 3.80E-08 18 79 "SLITRK1,LINC00461,FOXG1,ASTN1,ATP2B2,LMO3,PCDH11X,ROBO3,HAP1,GRIK2,MFSD2A,PAX6,ADGRG1,TOX,JAKMIP2,STMN4,RFX4,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.59E-10 1.60E-06 4.23E-09 3.80E-08 18 79 "TTYH1,ADGRV1,FABP7,FOXG1,DLL3,ATP2B2,NPAS3,WSCD1,GRIK2,CELF3,ADGRG1,ATCAY,MAPK10,HES5,DPYSL5,STMN4,ELAVL3,OLIG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.98E-10 1.77E-06 4.68E-09 4.20E-08 31 231 "DPF1,RTN3,KLHL32,RTN1,FHL1,SOX6,PPM1E,NLGN1,SCG3,ASTN1,B3GAT1,CCDC181,PHYHIPL,ILDR2,NPAS3,LMO3,GNG3,RFFL,PAX6,CDH8,JAM2,CADM1,KIAA1549L,NRXN2,SEMA5B,FAT3,FMN2,CTNND2,TUBB2B,PTPRZ1,ELAVL4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K3 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 4.60E-10 2.04E-06 5.39E-09 4.84E-08 26 168 "MEG3,CHST15,LRRTM4,CDC42BPA,NLGN1,YPEL4,ASTN1,CCDC181,NRG3,NPAS3,NFIA,SEMA4A,DDR1,DIRAS1,PSD3,MFSD2A,PCDH9,NLGN3,KIAA1549L,NRXN1,CCDC136,CELF5,FEZ1,FMN2,TOX,PTPRZ1" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.98E-10 2.66E-06 6.99E-09 6.28E-08 36 305 "SYNDIG1,MRVI1,ADCY2,CCDC80,ST8SIA1,MSR1,DACH2,CADPS,PALLD,DKK3,ADGRB2,NCAM1,SYT4,ANO4,VWC2,NRDC,GRIA1,GRIA4,GUCY1A1,PCDH9,DCLK1,TMEFF2,NEGR1,CNTN1,PRRX1,CNRIP1,SNCAIP,NKAIN4,ATRNL1,VCAN,SPIRE1,KCND3,NTM,PID1,CBLN2,EPB41L2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.07E-10 2.70E-06 7.05E-09 6.33E-08 13 39 "MEG3,RTN1,SCN3A,ANK3,NSG2,MYT1L,NCAM1,GPM6A,INA,KIAA0408,NTM,ELAVL4,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 6.07E-10 2.70E-06 7.05E-09 6.33E-08 13 39 "RTN1,ANK3,NSG2,SNAP25,SCN3B,KIF21B,SEPT3,SYT4,INA,CELF3,CELF5,ELAVL3,RCAN2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 6.15E-10 2.73E-06 7.14E-09 6.41E-08 48 491 "APC2,PLEKHG5,TESK2,MOBP,FOXG1,SGIP1,NTNG1,MADD,SORCS3,SNAP25,TMEM151A,ATP1A3,TNIK,GAD2,ARPP21,C11orf87,GFRA1,SEPT3,PCDH11X,KAZN,CACNA1A,CACNB2,HAP1,GRIK2,LEFTY2,PAX6,PRMT8,HPSE2,GDAP1L1,SERPINE2,NRXN2,CCDC136,CELF5,ATCAY,ATRNL1,IGSF1,MASP1,ZNF385B,KCNA6,SV2A,SRGAP3,RABGAP1L,ARNT2,RALGDS,RAP1GAP,L1CAM,ELAVL4,TMEM100" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 6.55E-10 2.91E-06 7.57E-09 6.80E-08 36 306 "APC2,MEG3,NDRG2,SLITRK1,CHST15,LRRTM4,LINC00461,FOXG1,APBB1,TAGLN3,NRG3,FYN,ATP2B2,NPAS3,NFIA,RHBDL3,PCDH11X,ASTN2,SEMA4A,GPM6A,HAP1,VSTM2A,PSD3,GRIK2,MFSD2A,ADGRG1,NRXN1,NEGR1,TJP2,MEAF6,FEZ1,MAPK10,BRINP3,STMN4,DTNA,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K5 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 7.03E-10 3.12E-06 8.11E-09 7.28E-08 22 124 "ADGRV1,FOXG1,SEMA6C,SCG3,ATP2B2,NFIA,CACNA1A,ACSL6,GRIK2,CELF3,TUB,GDAP1L1,KIAA1549L,NRXN2,FAT3,ATCAY,IGSF1,MAPK10,HES5,JAKMIP2,STMN4,ELAVL3" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_100 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_100 FaceBase_ST1 7.69E-10 3.42E-06 8.85E-09 7.95E-08 17 73 "FABP7,ERMN,LINC00461,MT3,ASCL1,SCG3,NPAS3,INA,PAX6,JAM2,FAM181B,FEZ1,HES5,TUBB2B,JAKMIP2,LMO1,ELAVL3" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500 Gudmap RNAseq 7.81E-10 3.47E-06 8.97E-09 8.05E-08 103 1522 "DPF1,SERPINA3,ABAT,EXTL1,MEG3,NDRG2,ADCY2,FABP7,GRAMD1B,LRRTM4,SEMA6A,PDZD4,SOX6,TRIM46,SGIP1,CNIH2,DOCK10,NTNG1,GAS7,CCDC80,DGKZ,NLGN1,ST8SIA1,KIAA1614,RUFY2,CCDC88A,GPR153,SLIT1,TAGLN3,ASTN1,SNAP25,TMEM151A,NRG3,PHYHIPL,PALLD,DKK3,MYBPC1,TNIK,SOX5,ZCCHC24,KIF21B,CADM3,ADAM15,ADGRB2,NCAM1,COLGALT2,NELL1,NFIA,C1QC,ADGRL3,KLHL4,GPM6A,NRGN,DDR2,PSD3,GRIA4,TF,TIE1,GUCY1A1,DAAM2,TNFRSF1B,REPS2,DCLK1,PDE1A,TMEFF2,JAM2,NLGN3,SERPINE2,CADM1,NRXN1,NEGR1,CPT1C,CCDC136,MICAL1,PRRX1,SLC36A4,CNRIP1,SNCAIP,TENM4,KCNT2,CSF3R,FEZ1,ATRNL1,VCAN,MASP1,BRINP3,TOX,LRRTM3,SHD,PTPRD,KCNA6,PTPRE,KCND3,PTPRZ1,RABGAP1L,CCDC3,TMEM255A,FAM13C,BEND5,SSPN,EFNA3,VWA5A,EPB41L2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.08E-10 3.59E-06 9.24E-09 8.29E-08 24 148 "EYA1,RTN1,FABP7,ANK2,CADPS,TAGLN3,SNAP25,SCN3B,NCAM1,C1QC,GNG3,INA,DCLK1,HPSE2,TMEFF2,CADM1,PRRX1,FAT3,FEZ1,VCAN,MAPK10,STMN4,DLG2,L1CAM" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.11E-10 3.60E-06 9.24E-09 8.29E-08 66 807 "EYA1,IL17D,MRVI1,SORCS1,SCN3A,KIAA1109,SEMA6A,SGIP1,ANK3,APC,NTNG1,JAKMIP3,SLC8A3,DACH2,CADPS,ASTN1,SNAP25,MEGF11,DKK3,MYH7,KIF1B,NPAS3,C11orf87,CLASP2,SMOC1,GFRA1,RGL1,NFIA,PCDH11X,CAMTA1,CAMSAP2,ADGRL3,VWC2,B4GALNT4,GRIA2,GRM3,GUCY1A1,CDH10,RBFOX2,PRRX1,FAT3,CRMP1,SNCAIP,TENM4,NKAIN4,FEZ1,PLCH2,VCAN,FMN2,CTNND2,MAPK8,TOX,PTCH1,JAKMIP2,ELMO1,KCND3,AK5,ARNT2,HS3ST4,CALN1,DNM2,FAM13C,ZYG11B,NUP214,CACNG7,EPB41" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.11E-10 3.60E-06 9.24E-09 8.29E-08 66 807 "LGR4,EYA1,RTN1,SORCS1,SCN3A,LRRTM4,KIAA1109,SGIP1,ANK3,APC,NTNG1,ST8SIA1,RUFY2,DACH2,ASTN1,SNAP25,DKK3,AHCYL1,KIF1B,DNER,NAP1L2,NPAS3,NASP,CLASP2,SMOC1,GFRA1,NFIA,PCDH11X,CAMSAP2,ADGRL3,VSTM2A,GRIA2,GRM3,INA,GUCY1A1,CDH10,RBFOX2,NLGN3,CADM1,PRRX1,FAT3,CRMP1,TENM4,NKAIN4,VCAN,RBPJ,FMN2,CTNND2,MAPK10,TOX,LRRTM3,ITGAV,JAKMIP2,ELMO1,PTPRD,KCND3,PTPRZ1,ARNT2,KCNMA1,HS3ST4,TMEM255A,DNM2,FAM13C,ABCC9,NUP214,ZNF248" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 8.69E-10 3.86E-06 9.85E-09 8.84E-08 13 40 "MEG3,RTN1,SCN3A,ANK3,TAGLN3,KIF21B,NCAM1,GNG3,GPM6A,GRIA2,INA,KIAA0408,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.69E-10 3.86E-06 9.85E-09 8.84E-08 13 40 "MEG3,RTN1,SCN3A,ANK3,TAGLN3,KIF21B,NCAM1,GNG3,GPM6A,GRIA2,INA,KIAA0408,ELAVL4" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000 FaceBase_RNAseq 8.77E-10 3.90E-06 9.91E-09 8.90E-08 76 994 "TTYH1,APC2,CEND1,ADGRV1,CDC7,ERMN,TUBB4A,FHL1,FOXM1,NTNG1,CCDC80,SHTN1,NSG2,DLL3,TMEM108,PHYHIPL,ATP2B2,SOX5,ILDR2,SALL3,TTLL9,LMO3,C11orf87,RGL1,SEPT3,AJAP1,GLS,ZNF638,ROBO3,GNG3,WWC1,TCF7L2,DIRAS1,HAP1,PTBP2,CECR2,RFFL,GRIK2,INA,CELF3,CDK11B,PAX6,TPM3,PRMT8,ZMYND8,TUB,KIAA1549L,NRXN2,ANLN,NMT2,NXPH1,POU3F4,NKAIN4,NCAN,CTNND1,CTNND2,HES5,MASP1,ZBTB16,DPYSL5,CA10,JAKMIP2,SHD,RGMA,CDH20,PTPRZ1,KCNK1,CAB39L,DTNA,ST8SIA3,RFX4,ELAVL3,OLIG2,PLEKHO1,EPB41,SEZ6" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_cfr-2X-p05 Pluripotent Stem Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.43E-10 4.19E-06 1.06E-08 9.55E-08 66 810 "TTYH1,ECSIT,FABP7,NLGN4X,DRAXIN,SEMA6A,FHL1,CNIH2,SESN3,TACC2,SORBS1,CCDC88A,SCG3,DDX25,ALDH4A1,ATP1A2,ATP1A3,TNIK,JPH4,MIR4697HG,ADAM15,GART,NAP1L2,NASP,NCDN,PHLDB1,RND1,SEPT3,RHBDL3,GNG4,UNC5D,WWC1,WSCD1,GPR19,DIRAS1,PTBP2,SYT6,MFSD2A,ZDHHC22,DCLK1,MAGI1,ZMYND8,CAMKV,PIK3CD,CPT1C,TJP2,ATCAY,CRMP1,RIMS4,RBPJ,IGSF1,FAM131B,ECE2,TOX,JAKMIP2,PTPRZ1,SV2A,RABGAP1L,NAV2,KCNQ2,NKAIN1,FAM57B,ARHGEF10L,CACNG7,FGFBP3,LINC00599" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.72E-10 4.32E-06 1.09E-08 9.81E-08 70 884 "TTYH1,EPS8,ABAT,CEND1,MEG3,EYA1,F3,FABP7,PNMA8B,GRAMD1B,ADORA1,BCAR3,SOX6,SEMA6C,USP28,PPFIA1,SH3GL2,DOCK10,GAS7,DGKD,ST8SIA1,SHTN1,KIAA1614,CADPS,CSPG5,MTR,ATP1A2,FYN,TNIK,SOX5,SOX10,FXYD6,SMOC1,NELL1,ADHFE1,NFIA,OS9,SEMA4A,PSRC1,GPM6B,PADI2,TPD52,PDE2A,FNDC5,ADGRG1,JAM2,SERPINE2,FADS2,COL9A2,MICAL2,VCAN,DOCK7,MASP1,TOX,TUBB2B,LRRTM3,PTCH1,JAKMIP2,ELMO1,PTPRD,PTPRE,PLPPR4,KCNH1,SRGAP3,KCNK2,NAV2,GNE,DTNA,SIDT2,TMEM100" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_500 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_500 FaceBase_ST1 1.14E-09 5.04E-06 1.27E-08 1.14E-07 38 342 "SDE2,FABP7,TUBB4A,APBA2,MT3,CCDC88A,ASCL1,SCG3,ARFGAP1,PHYHIPL,NKX6-2,FGF17,SEPT3,WSCD1,TCF12,USP2,MFSD2A,INA,PAX6,IGSF21,PCDH9,JAM2,NMT2,FAM181B,NECAB2,FAT3,POU3F4,FEZ1,PRKCZ,HES5,ZBTB16,TUBB2B,JAKMIP2,SNX27,LMO1,ELAVL3,ROM1,EN2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.14E-09 5.05E-06 1.27E-08 1.14E-07 67 832 "DPF1,ACLY,RTN3,CLIP1,KLHL32,ADCYAP1R1,FHL1,SOX6,PPFIA1,PPM1E,SESN3,NLGN1,ST3GAL3,KIAA1614,YPEL4,CCDC88A,SCG3,ASTN1,B3GAT1,ADGRA1,CCDC181,PHYHIPL,GABBR1,ILDR2,NEK6,NPAS3,NASP,LMO3,ARHGEF7,GNG3,CACNA1A,CACNB2,TCF7L2,PTBP2,NUMA1,RFFL,GRIK4,CDK11B,PAX6,CDH8,MAGI1,PRMT8,JAM2,HPCA,KIAA1549L,SEMA5B,CCSER2,NECAB2,IFFO1,FAT3,RNF14,PPP2R5C,FMN2,CTNND2,TOX,GON4L,TUBB2B,JAKMIP2,LRP8,PTPRZ1,KCNN3,KIF2A,ATN1,RFX4,ZNF248,EFNA3,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.21E-09 5.36E-06 1.35E-08 1.21E-07 17 75 "MAP6,RTN1,SCN3A,ANK3,APBB1,NSG2,SNAP25,SCN3B,DNER,FXYD6,NCAM1,SYT4,GPM6A,CELF3,STMN4,CBLN2,ELAVL3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.21E-09 5.37E-06 1.35E-08 1.21E-07 23 139 "KLHL32,SOX6,PPM1E,SCG3,ASTN1,PHYHIPL,ILDR2,NASP,GNG3,TCF7L2,CDK11B,MAGI1,PRMT8,JAM2,KIAA1549L,NRXN2,SEMA5B,FAT3,FMN2,CTNND2,JAKMIP2,RFX4,ELAVL4" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.21E-09 5.38E-06 1.35E-08 1.21E-07 66 815 "MEG3,ARID1A,FABP7,PNMA8B,CHST15,DRAXIN,LINC00461,KIAA1109,SFPQ,ITSN1,PKP4,NSG2,DACH2,CADPS,SCMH1,ASCL1,SPHKAP,TAGLN3,DLL3,SNAP25,FYN,MYBPC1,SOX5,ZCCHC24,ILDR2,KIF1B,DNER,NAP1L2,NASP,RGL1,NEUROD1,PCDH11X,BTRC,KLHL4,PCDH8,PCDH9,CDH10,DCLK1,RBFOX2,PRMT8,CADM1,NMT2,PRRX1,NSD2,CRMP1,TENM4,DZIP3,MAPK8,MAPK10,PUM1,HES5,KIAA0408,FGFR1OP2,WBP1L,JAKMIP2,CEP170,ZC3H11A,PTPRZ1,SNX27,TMEM255A,SLC17A6,JMJD1C,VANGL2,ELAVL3,ELAVL4,EPB41L2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.53E-09 6.81E-06 1.70E-08 1.52E-07 22 129 "EYA1,WAC,SORCS1,SCN3A,SGIP1,NTNG1,CADPS,ASTN1,NAP1L2,NPAS3,PCDH11X,ACSL6,GPR17,GRM3,CDH10,DCLK1,NEGR1,FEZ1,JAKMIP2,LRP8,KCNK2,SLC6A15" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.57E-09 6.96E-06 1.73E-08 1.55E-07 18 86 "MRVI1,ADCY2,CCDC80,DACH2,CADPS,DKK3,ANO4,VWC2,GUCY1A1,TMEFF2,NEGR1,CNTN1,PRRX1,CNRIP1,NKAIN4,VCAN,KCND3,EPB41L2" Coexpression Atlas Arv_SC-hpx_blastocyst_1000 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.63E-09 7.26E-06 1.80E-08 1.61E-07 75 989 "RIMKLA,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,SEMA6A,C1orf61,PDZD4,SH3GL2,JAKMIP3,SLC1A6,SLC6A9,MT3,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,SALL3,LHFPL4,RCOR2,SEPT3,ACSBG1,ABCC8,PCDH11X,C1QC,GNG4,UNC5D,KLHL4,GPM6B,HAP1,CECR2,SYT6,GRIA4,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,A2ML1,SULT4A1,CELF5,PMS2,NECAB2,FAT3,BTBD17,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,TUBB2B,LRRTM3,CADM2,KCNQ2,NKAIN1,HS3ST4,DPP6,RET,USH1C,LINC00599,RASGRP2,SEZ6" Coexpression Atlas Arv_SC-H9hpx_1000 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000 PCBC 1.63E-09 7.26E-06 1.80E-08 1.61E-07 75 989 "RIMKLA,ADGRV1,ADCY2,RYR1,FABP7,NLGN4X,SEMA6A,C1orf61,PDZD4,SH3GL2,JAKMIP3,SLC1A6,SLC6A9,MT3,SCG3,CSPG5,SLCO1A2,DDX25,B3GAT1,IGSF9B,SNCB,SALL3,LHFPL4,RCOR2,SEPT3,ACSBG1,ABCC8,PCDH11X,C1QC,GNG4,UNC5D,KLHL4,GPM6B,HAP1,CECR2,SYT6,GRIA4,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CHGA,DLGAP3,GDAP1L1,CAMKV,A2ML1,SULT4A1,CELF5,PMS2,NECAB2,FAT3,BTBD17,NKAIN4,KCNT2,ATRNL1,NCAN,RIMS4,RAB39A,IGSF1,NOS1AP,RIMS3,TUBB2B,LRRTM3,CADM2,KCNQ2,NKAIN1,HS3ST4,DPP6,RET,USH1C,LINC00599,RASGRP2,SEZ6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.86E-09 8.27E-06 2.04E-08 1.83E-07 17 77 "RTN1,ANK3,APC,NSG2,FYN,SCN3B,JPH4,NCAM1,SEPT3,ARHGEF7,INA,CELF3,NEGR1,CELF5,FAT3,JAKMIP2,ELAVL3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.96E-09 8.71E-06 2.15E-08 1.93E-07 63 770 "PRR5L,EYA1,SORCS1,SCN3A,SGIP1,APC,NTNG1,CACHD1,ZNF365,MIER1,DACH2,CADPS,SCMH1,DKK3,TNIK,ILDR2,AHCYL1,SALL3,NPAS3,NASP,CLASP2,NFIA,SEMA4A,GNG4,CAMSAP2,UNC5D,ADGRL3,TCF7L2,B4GALNT4,DDR2,GRIA2,GRM3,TF,ZFP91,PAH,DCLK1,RBFOX2,CELF5,SLC25A27,PRRX1,VCAN,RBPJ,FMN2,CTNND2,MAPK8,TOX,LRRTM3,DNAJC6,PTHLH,ITIH2,LRP8,CEP170,MAGI2,KCNA4,PTPRO,PTPRZ1,NTM,CCDC3,TMEM255A,DNM2,FAM13C,NUP214,CACNG7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 2.08E-09 9.22E-06 2.27E-08 2.03E-07 30 233 "KLHL32,SOX6,PPM1E,NLGN1,SCG3,ASTN1,B3GAT1,ADGRA1,PHYHIPL,ILDR2,NPAS3,NASP,GNG3,PTBP2,CDK11B,PCDH9,CDH8,MAGI1,JAM2,KIAA1549L,SEMA5B,FAM181B,FAT3,FMN2,CTNND2,TOX,TUBB2B,JAKMIP2,PTPRZ1,RFX4" Coexpression Atlas geo_heart_1000_K5 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.13E-09 9.45E-06 2.31E-08 2.07E-07 43 428 "MAPT,DUSP27,SYNDIG1,ACTN2,RXRG,AGT,SCN4B,SORBS1,SLC1A7,MT3,SPHKAP,KBTBD12,IGSF9B,ATP1A3,B3GALT2,NCAM1,ADHFE1,FAM69C,VWC2,CACNB2,GPR17,DIRAS1,CAMK2A,PCDHGA3,TF,USP2,TNS1,PDE1C,FNDC5,ANO5,MS4A7,PRRX1,ETNPPL,PROX1,MASP1,DKFZp779M0652,KCND3,KCNJ11,PYGM,CRTAC1,EEF1A2,SSPN,RCAN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.13E-09 9.45E-06 2.31E-08 2.07E-07 27 193 "EYA1,SORCS1,SCN3A,SGIP1,ANK2,ZNF365,DACH2,CADPS,ASTN1,NAP1L2,NPAS3,CAMTA1,GPR17,GRIA2,GRM3,DCLK1,NEGR1,CELF5,PRRX1,TENM4,FMN2,LRRTM3,JAKMIP2,LRP8,ARNT2,KCNK2,EFNA3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 2.19E-09 9.71E-06 2.37E-08 2.13E-07 53 595 "DPF1,MBP,RTN3,ARID1A,CLIP1,ADCYAP1R1,WAC,SOX6,PKP4,PPM1E,APC,ST8SIA1,SLC1A2,BCO1,ARHGAP5,SCG3,B3GAT1,ATP1A3,PHYHIPL,SON,CAB39,ILDR2,NPAS3,ACSBG1,ARHGEF7,GNG3,GOLGB1,ZEB1,ZFP91,CDK11B,CDH8,HMGB1,JAM2,ZFYVE9,NRXN2,SEMA5B,FAM181B,MEAF6,KCNT2,MICAL2,CTNND2,EDRF1,TUBB2B,JAKMIP2,PRDM2,CEP170,PTPRZ1,NKAIN1,FAM13C,ZYG11B,RFX4,ELAVL4,SEZ6" Coexpression Atlas PCBC_DE_fibroblast_500 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_500 PCBC 2.25E-09 9.98E-06 2.43E-08 2.18E-07 47 494 "TMEM74,ADGRV1,ADCY2,RXRG,FABP7,SORCS1,ERMN,NLGN4X,SEMA6A,UNC79,MOBP,C1orf61,PDZD4,SLC7A14,SCG3,DDX25,B3GAT1,SALL3,LHFPL4,FGF17,SYT4,NODAL,KLHL4,GPM6A,CCKBR,LEFTY2,CDH8,SEZ6L,CHGA,SEMA5B,A2ML1,CELF5,PACSIN1,ETNPPL,TENM4,KCNT2,NCAN,RIMS4,FMN2,ANKS1B,TUBB2B,CADM2,KCNQ2,SLC25A48,CALN1,RET,ELAVL4" Coexpression Atlas ratio_SC_vs_MESO_1000_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 2.46E-09 1.09E-05 2.65E-08 2.38E-07 23 144 "MAPT,FAM43B,SCN4B,SORBS1,TMEM151A,ATP1A2,ATP1A3,CADM3,CPLX2,DNER,ALDH1L1,ABCC8,SYT4,CNTN2,DIRAS1,NEGR1,ST8SIA5,CABP1,CP,NKAIN4,SLC45A1,PTPRO,PYGM" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k4 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.61E-09 1.16E-05 2.81E-08 2.52E-07 35 307 "WAC,SORCS1,SCN3A,SGIP1,NTNG1,CADPS,ASPH,ASTN1,MEGF11,GART,NAP1L2,NPAS3,C11orf87,GFRA1,PCDH11X,ACSL6,B4GALNT4,GRM3,GUCY1A1,CDH10,DCLK1,PDE1A,CADM1,NEGR1,BTF3L4,FEZ1,JAKMIP2,LRP8,CEP170,KCNK2,GOPC,SLC6A15,ST8SIA3,ATL1,ABI2" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k4 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.68E-09 1.19E-05 2.87E-08 2.58E-07 27 195 "SYNDIG1,MRVI1,ADCY2,CCDC80,ST8SIA1,MSR1,DACH2,CADPS,DKK3,ADGRB2,ANO4,VWC2,GRIA1,GRIA4,GUCY1A1,PCDH9,TMEFF2,NEGR1,CNTN1,PRRX1,CNRIP1,NKAIN4,ATRNL1,SPIRE1,KCND3,NTM,EPB41L2" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k1_1000 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.81E-09 1.25E-05 3.01E-08 2.70E-07 18 89 "MAPT,ATAT1,FABP7,LINC00461,ASCL1,TAGLN3,DLL3,SNAP25,SOX5,NEUROD1,GNG3,INA,CRMP1,KIAA0408,TUBB2B,RFX4,VANGL2,ELAVL4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500 FaceBase_RNAseq 3.23E-09 1.43E-05 3.45E-08 3.09E-07 46 483 "PRR5L,EMID1,ACTN2,NDRG2,ADCY2,CHST15,DOCK10,NTNG1,CCDC80,NLGN1,SLC1A2,ASTN1,NRG3,JPH4,TTLL9,ADGRB2,NPAS3,NFIA,PCDH11X,C1QC,SEMA4A,ADGRL3,ACSL6,NRGN,AZIN2,CAMK2A,GRIA1,MFSD2A,REPS2,PCDH9,PDE1A,KIAA1549L,FLRT1,FEZ1,FMN2,MASP1,TOX,ZNF385B,PMEPA1,CADM2,SV2A,CCDC3,PCDH15,DLG2,VWA5A,BAALC" Coexpression Atlas JC_iEC_2500_K3 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 4.00E-09 1.78E-05 4.26E-08 3.82E-07 35 312 "FAM43B,RTN1,RXRG,SCN4B,PI16,ST8SIA1,SLC1A2,SLC1A7,CADPS,SLN,PALLD,MYBPC1,SOX10,NCAM1,ABCC8,SYT4,CNTN2,CACNA1E,VWC2,TF,TGFBR3,TLL2,MAEL,TNFRSF1B,TNS1,FNDC5,JAM2,PROX1,MASP1,PSD,PTPRO,KCND3,PYGM,RAB3IL1,RFX4" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k2_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.05E-09 1.80E-05 4.31E-08 3.87E-07 16 71 "RTN1,SORCS1,SCN3A,SNAP25,NAP1L2,NPAS3,GFRA1,PCDH11X,VSTM2A,GRM3,INA,GUCY1A1,CDH10,CRMP1,JAKMIP2,HS3ST4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000 FaceBase_RNAseq 4.09E-09 1.82E-05 4.34E-08 3.90E-07 74 991 "SDE2,ADGRV1,RTN1,SLITRK1,ADCYAP1R1,FABP7,TUBB4A,DISP3,FHL1,ZCCHC17,SORBS1,PKNOX2,GPR153,SCG3,SLCO1A2,DLL3,B3GAT1,ATM,PHYHIPL,ILDR2,AHCYL1,NMNAT2,TTLL9,GART,NASP,LMO3,RCOR2,FGF17,AJAP1,WWC1,WSCD1,ACSL6,GPR19,HAP1,CECR2,GRIK3,MFSD2A,INA,CELF3,PRMT8,ADGRG1,CA14,JAM2,NLGN3,CADM1,NRXN2,SEMA5B,FLRT1,FAM181B,CELF5,ATCAY,POU3F4,CRMP1,KCNT2,NCAN,CTNND2,MAPK10,HES5,PROX1,ZBTB16,DPYSL5,TOMM20,CA10,JAKMIP2,CDH20,SMG7,SRGAP3,NAV2,SUSD4,DTNA,ST8SIA3,RFX4,LPAR6,LRRC23" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k1 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.35E-09 1.93E-05 4.60E-08 4.13E-07 20 113 "MAPT,RTN1,SLITRK1,FABP7,SORCS1,ANK2,SPHKAP,SNAP25,SCN3B,C11orf87,NFIA,DCLK1,NEGR1,CNTN1,CRMP1,NRSN1,MAPK10,KCNK2,ST8SIA3,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.64E-09 2.51E-05 5.94E-08 5.33E-07 62 773 "EPS8,ACER3,LGR4,MEG3,NDRG2,ADCY2,ADCYAP1R1,FABP7,PNMA8B,GRAMD1B,KIAA1109,SEMA6A,NTNG1,CCDC80,GPAM,PKNOX2,ARFGAP1,SORCS3,ATP1A3,PALLD,ZCCHC24,NCAM1,SMOC1,ACSBG1,NFIA,PCDH11X,ADGRL3,GPM6B,CACNB2,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,REPS2,PCDH9,PDE1A,HPSE2,TMEFF2,JAM2,SERPINE2,ANLN,FADS2,FAT3,SNCAIP,TENM4,MICAL2,ATRNL1,VCAN,MASP1,SYTL2,LRRTM3,PTCH1,PMEPA1,KCND3,SRGAP3,TMEM255A,ABCC9,SLC6A15,CACNG7,EPB41L2,RASGRP2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k2_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.65E-09 2.51E-05 5.94E-08 5.33E-07 22 138 "RTN1,SORCS1,SCN3A,NTNG1,ST8SIA1,ASTN1,SNAP25,DNER,NAP1L2,NPAS3,GFRA1,PCDH11X,VSTM2A,GRM3,INA,GUCY1A1,CDH10,CADM1,CRMP1,MAPK10,JAKMIP2,HS3ST4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.66E-09 2.51E-05 5.94E-08 5.33E-07 12 38 "MEG3,RTN1,SCN3A,TAGLN3,NCAM1,SEPT3,GPM6A,GRIA2,INA,PANTR1,ELAVL3,ELAVL4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_1000 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.83E-09 2.59E-05 6.11E-08 5.48E-07 69 904 "MAP6,ACHE,CEND1,EYA1,CSMD3,RTN1,ADCYAP1R1,FABP7,TUBB4A,LRRC7,APBB1,CCDC80,SLC7A14,CADPS,SCG3,TAGLN3,DDX25,SNAP25,PHYHIPL,SCN3B,CADM3,TTC9B,NCAM1,GFRA1,SEPT3,C1QC,ASTN2,GNG3,ADGRL3,B4GALNT4,DDR2,GRIA2,TF,INA,TMEM9,CELF3,DCLK1,LGI1,ACOT7,HPSE2,TMEFF2,GDAP1L1,SERPINE2,CADM1,PRRX1,FAT3,PNKD,CRMP1,NKAIN4,FEZ1,VCAN,SDC3,NRSN1,MAPK10,ECE2,MASP1,TOX,DPYSL5,TUBB2B,STMN4,SV2A,DLG2,TMEM255A,DPP6,L1CAM,RET,CACNG7,ELAVL4,BSCL2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.79E-09 3.02E-05 7.10E-08 6.38E-07 66 851 "EPS8,PRR5L,ACER3,EYA1,GALNT13,SORCS1,TESK2,SCN3A,LRRTM4,SGIP1,ANK2,PPM1E,ZNF365,MIER1,YPEL4,CCDC88A,SLC14A1,DACH2,CADPS,ASPH,ASTN1,SON,KIF1B,DNER,NAP1L2,NPAS3,CAMTA1,GNG4,UNC5D,ADGRL3,TBX15,GPR17,DDR2,PSD3,GRIA2,GRM3,FBXL16,PCDH8,DCLK1,PFKFB3,NLGN3,NEGR1,CELF5,PRRX1,TENM4,VCAN,FMN2,TOX,LRRTM3,JAKMIP2,LRP8,MAGI2,BLOC1S6,KCNA4,PTPRE,NTM,RABGAP1L,ARNT2,KCNK2,TMEM255A,PARP11,FAM13C,PAK5,SEC61A2,EFNA3,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.69E-09 3.42E-05 8.02E-08 7.20E-07 16 74 "RTN1,ANK2,ANK3,NSG2,SNAP25,SCN3B,SYT4,GNG4,INA,NRXN1,DNAJC12,CELF5,PIANP,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.90E-09 3.51E-05 8.20E-08 7.36E-07 12 39 "RTN1,SCN3A,ANK3,NSG2,SNAP25,SCN3B,NCAM1,SYT4,GPM6A,CELF3,STMN4,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.90E-09 3.51E-05 8.20E-08 7.36E-07 12 39 "RTN1,ANK2,ANK3,NSG2,SNAP25,SCN3B,SYT4,GNG4,DNAJC12,CELF5,ELAVL3,RCAN2" Coexpression Atlas GSM854299_500 "Plasmacytoid, DC.pDC.8+.SLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-3" "Immgen.org, GSE15907" 8.17E-09 3.63E-05 8.46E-08 7.60E-07 41 415 "EYA1,LDLRAD3,SNX30,FOXRED2,SCN3A,FGR,PDZD4,SELL,ITSN1,PPM1E,GAS7,ST8SIA1,ARHGAP5,CCDC88A,ASPH,ATP1A3,FYN,ZCCHC24,NEK6,GPR162,RGL1,GPM6B,CACNA1E,DDR1,CLEC9A,CYB561A3,ATP13A2,PADI2,TNS1,TPD52,FADS2,VAV2,P2RY12,PACSIN1,CTNND2,SIRPA,PTAFR,LRP8,SRGAP3,RABGAP1L,GNE" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 9.27E-09 4.12E-05 9.58E-08 8.60E-07 23 154 "TTYH1,MEG3,ADGRV1,FABP7,C1orf61,ILDR2,RND1,SYT4,TCF12,PCDH8,LGI1,LINC01102,ANLN,POU3F2,HES5,TOX,PTCH1,RGMA,PTPRZ1,PANTR1,RFX4,FGFBP3,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.16E-08 5.14E-05 1.19E-07 1.07E-06 16 76 "TTYH1,MEG3,FABP7,C1orf61,ILDR2,PCDH8,LINC01102,POU3F2,HES5,PTCH1,RGMA,PTPRZ1,PANTR1,RFX4,FGFBP3,EN2" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.17E-08 5.21E-05 1.21E-07 1.08E-06 26 195 "SYNDIG1,MRVI1,ADCY2,SCN3A,NTNG1,DACH2,CADPS,GPR153,ASPH,PCDH11X,GPM6B,VWC2,TCF12,GRIA4,TMEFF2,NEGR1,CNTN1,MICAL1,PRRX1,CNRIP1,ATRNL1,VCAN,KCND3,KCNK2,FAM13C,EPB41L2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.34E-08 5.94E-05 1.37E-07 1.23E-06 62 791 "MEG3,ADGRV1,ADCY2,LRRTM4,ANK2,SESN3,NTNG1,ST8SIA1,NSG2,DACH2,CADPS,SLN,MTR,ASTN1,ZCCHC24,NEK6,ADGRB2,NAP1L2,FXYD6,NFIA,ADGRL3,KLHL4,ANO4,GPM6B,VWC2,TCF7L2,DDR2,GRIA1,GRIA4,GRM3,USP2,REPS2,PCDH8,CDH10,DCLK1,PDE1A,CADM1,NEGR1,CPT1C,FTO,BTF3L4,PRRX1,MED1,RNF14,RBPJ,PTCH1,PMEPA1,HP1BP3,RGMA,CEP170,PTPRD,SRGAP3,NTM,TMEM255A,RALGDS,FAM13C,RTN4,ATL1,ZNF248,SSPN,EFNA3,VWA5A" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_1000_J DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.44E-08 6.39E-05 1.47E-07 1.32E-06 61 774 "EPS8,SERPINA3,MBP,IL17D,MRVI1,NDRG2,RTN1,SCN3A,FHL1,ANK1,PI16,SH3GL2,APC,SORBS1,SLC14A1,DACH2,SNAP25,DKK3,SCN3B,TNIK,ILDR2,MYH7,DNER,RAP1GAP2,C11orf87,CLASP2,NFIA,POPDC3,SEMA4A,GNG4,CAMSAP2,PRUNE2,DDR2,TF,TGFBR3,REPS2,TNS1,RBFOX2,PDE4B,PIRT,CNTN1,PRRX1,MFSD4A,OSBPL3,CTNND2,MAPK10,ZBTB16,SYTL2,DNAJC6,PTHLH,KCND3,RABGAP1L,KCNK1,KCNMA1,DNM2,FAM13C,DTNA,ABCC9,RET,TTLL7,SH3GLB1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.54E-08 6.84E-05 1.57E-07 1.41E-06 40 408 "EYA1,IL17D,SCN3A,KIAA1109,SGIP1,ANK3,APC,NTNG1,JAKMIP3,DACH2,ASTN1,DKK3,MYH7,NPAS3,SMOC1,GFRA1,NFIA,PCDH11X,CAMSAP2,ADGRL3,B4GALNT4,GRIA2,GRM3,CDH10,RBFOX2,PRRX1,FAT3,SNCAIP,PLCH2,VCAN,FMN2,TOX,JAKMIP2,ELMO1,ARNT2,HS3ST4,CALN1,DNM2,NUP214,CACNG7" Coexpression Atlas PCBC_ratio_EB_vs_SC_cfr-2X-p05 Embryoid Body Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.59E-08 7.05E-05 1.62E-07 1.45E-06 113 1823 "TTYH1,EPS8,ABAT,ATAT1,WLS,NDRG2,F3,CLIP1,PLEKHG5,RTN1,CHST15,AGT,BCAR3,FHL1,SEMA6C,CNIH2,APBA2,APBB1,SESN3,GAS7,CCDC80,ST3GAL3,NBPF1,PKNOX2,NSG2,SCMH1,SLIT1,MTR,PALLD,DKK3,WDTC1,ZCCHC24,CADM3,ILDR2,ZSWIM8,NEK6,STARD10,DNER,FXYD6,NCAM1,GPR162,ERBIN,GFRA1,NELL1,RGL1,FAM168A,GLS,NHLH1,DDHD2,ROBO3,MYRF,CNTN2,ADGRL3,GPM6A,ATF7,TCF12,PCDHGA3,DDR2,PSD3,TF,OLR1,TGFBR3,INA,GUCY1A1,CELF3,DAAM2,TNS1,ARHGAP19,LGI1,FNDC5,ADGRG1,SCRG1,PFKFB3,JAM2,SERPINE2,CADM1,FAM181B,C11orf49,COL9A2,PRRX1,POU3F2,RNF14,SNCAIP,TENM4,NKAIN4,FEZ2,ATRNL1,SDC3,CTNND2,DPYSL5,SIRPA,PTCH1,ITGAV,PMEPA1,BDNF-AS,PRDM2,HP1BP3,STMN4,PTPRD,CCDC3,RAB3IL1,PID1,PARP11,RALGDS,GOPC,BEND5,RFX4,EEF1A2,SIDT2,SH3GLB1,ELAVL3,LRRC23,BAALC" Coexpression Atlas ratio_ECTO_vs_SC_1000_K3 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 1.73E-08 7.70E-05 1.76E-07 1.58E-06 44 476 "C1orf194,MAP6,WLS,SLC30A10,SOX6,SESN3,CCDC80,BCO1,PKNOX2,TAGLN3,PHYHIPL,SOX5,ILDR2,LMO3,COLGALT2,STOX1,SMOC1,GPR162,KIRREL3,NHLH1,DCLK2,AZIN2,CELF3,KCNK10,PAX6,LGI1,IGFN1,COL9A2,POU3F2,MAPK10,HES5,DPYSL5,ZNF385B,STMN4,KCNA1,OLFM3,CDH20,CCDC3,TMEM255A,CAMK1G,RFX4,RLBP1,SLC4A10,PRRT4" Coexpression Atlas GSM854297_500 "Plasmacytoid, DC.pDC.8+.MLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.77E-08 7.84E-05 1.79E-07 1.61E-06 40 410 "EYA1,LDLRAD3,SNX30,CHST15,SCN3A,FGR,PDZD4,SELL,ITSN1,PPM1E,GAS7,ST8SIA1,ARHGAP5,CCDC88A,ASPH,ATP1A3,FYN,ZCCHC24,NEK6,RGL1,GPM6B,CACNA1E,DDR1,CLEC9A,CYB561A3,ATP13A2,PADI2,TNS1,TPD52,FADS2,VAV2,P2RY12,PACSIN1,CTNND2,SIRPA,PTAFR,LRP8,SRGAP3,RABGAP1L,GNE" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE76381_iPSMoleculeCountsPMLog2 1.87E-08 8.29E-05 1.89E-07 1.69E-06 19 111 "RTN1,ANK2,ANK3,NSG2,SNAP25,SCN3B,LMO3,SYT4,GNG4,INA,NRXN1,DNAJC12,CELF5,BDNF-AS,SLC17A6,PIANP,ELAVL3,ELAVL4,RCAN2" Coexpression Atlas PCBC_EB_100 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_100 PCBC 1.95E-08 8.66E-05 1.97E-07 1.77E-06 18 100 "FABP7,NSG2,PHYHIPL,NELL1,SYT4,CNTN2,GPM6A,TF,CELF3,SCRG1,GDAP1L1,POU3F2,NKAIN4,STMN4,KCNQ2,RFX4,ELAVL3,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.17E-08 9.64E-05 2.19E-07 1.96E-06 29 243 "EYA1,SORCS1,SCN3A,SGIP1,NTNG1,JAKMIP3,CADPS,ASTN1,SNAP25,NPAS3,CAMTA1,ADGRL3,VWC2,B4GALNT4,GRIA2,GRM3,GUCY1A1,CDH10,PRRX1,CRMP1,SNCAIP,TENM4,FEZ1,FMN2,TOX,PTCH1,JAKMIP2,HS3ST4,CACNG7" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.20E-08 9.77E-05 2.21E-07 1.98E-06 43 463 "EYA1,CSMD3,RTN1,FABP7,TUBB4A,CCDC80,CADPS,SCG3,TAGLN3,SNAP25,SCN3B,NCAM1,GFRA1,SEPT3,C1QC,ASTN2,GNG3,B4GALNT4,INA,CELF3,DCLK1,ACOT7,HPSE2,TMEFF2,GDAP1L1,SERPINE2,CADM1,PRRX1,FAT3,CRMP1,NKAIN4,FEZ1,VCAN,NRSN1,MAPK10,MASP1,TUBB2B,STMN4,TMEM255A,L1CAM,RET,CACNG7,ELAVL4" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.31E-08 1.03E-04 2.32E-07 2.08E-06 47 532 "EPS8,ACTN2,ADCY2,MOBP,SGIP1,SH3GL2,DOCK10,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,DKK3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,GRIK4,ATP13A2,OPCML,TMEM25,DAAM2,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,PMEPA1,CADM2,LRP8,KCNA6,CCDC3,PCDH15,PEX5,DLG2,RALGDS,SSPN,PRRT4,EPB41L1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.55E-08 1.13E-04 2.55E-07 2.29E-06 21 137 "EYA1,SCN3A,SGIP1,NTNG1,JAKMIP3,DACH2,ASTN1,NPAS3,ADGRL3,B4GALNT4,GRIA2,GRM3,CDH10,PRRX1,SNCAIP,FMN2,TOX,JAKMIP2,HS3ST4,CALN1,CACNG7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 2.61E-08 1.16E-04 2.60E-07 2.34E-06 11 35 "MAP6,RTN1,SCG3,TAGLN3,NCAM1,SYT4,GNG3,CNTN2,INA,SLC17A6,ELAVL3" Coexpression Atlas ratio_SC_vs_DE_2500_K1 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_2500_k-means-cluster#1 PCBC 3.03E-08 1.35E-04 3.02E-07 2.71E-06 52 625 "TTYH1,RIMKLA,CEND1,RYR1,DRAXIN,ACTL6B,HPCAL4,SLITRK3,BCAN,LRRC55,KIF21B,JPH4,LHFPL4,LMO3,RND1,SEPT3,SLCO1C1,RHBDL3,PCDH11X,LUZP2,ACSL6,TMEM151B,SYT6,VSTM2A,GRIA4,GRIN1,ZDHHC22,PAH,HRH3,CHGA,CHRNB2,NLGN3,CAMKV,BTBD17,POU3F4,KCNT2,RIMS4,RAB39A,PRKCG,TOX,PHYHIP,TUBB2B,LRRTM3,JAKMIP2,PARD6A,PTPRZ1,KCNN3,ATL1,CACNG7,FGFBP3,LINC00599,SEZ6" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.12E-08 1.39E-04 3.10E-07 2.78E-06 23 164 "MRVI1,ADCY2,CCDC80,DACH2,CADPS,DKK3,NCAM1,NFIA,CAMSAP2,ANO4,VWC2,GUCY1A1,PCDH8,TMEFF2,NEGR1,CNTN1,PRRX1,CNRIP1,NKAIN4,VCAN,PTPRO,KCND3,EPB41L2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.15E-08 1.40E-04 3.11E-07 2.79E-06 15 71 "RTN1,SCN3A,ANK3,NSG2,SNAP25,SCN3B,NCAM1,SYT4,GPM6A,CELF3,CRMP1,SLC45A1,KIAA0408,STMN4,ELAVL3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 3.15E-08 1.40E-04 3.11E-07 2.79E-06 15 71 "FHL1,SLC1A2,ATP1A3,LMO3,GRIK4,PAX6,PRMT8,HPCA,PLCH2,MASP1,KCNN3,RFX4,EFNA3,ELAVL4,PRRT4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K4 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 3.21E-08 1.43E-04 3.17E-07 2.84E-06 17 92 "CHST15,NLGN1,ASTN1,NRG3,NPAS3,NFIA,SEMA4A,ACSL6,AZIN2,MFSD2A,PCDH9,KIAA1549L,FLRT1,FEZ1,FMN2,TOX,SV2A" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_1000 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.52E-08 1.56E-04 3.47E-07 3.11E-06 64 850 "SDE2,ABAT,LGR4,MEG3,F3,ADCY2,FABP7,TUBB4A,SOX6,RASA3,DOCK10,GAS7,CCDC80,CACHD1,LRRC4C,ST8SIA1,PKNOX2,CADPS,DDX25,MTR,TMEM108,FYN,PALLD,MYBPC1,TNIK,SOX5,ZCCHC24,NEK6,NCAM1,SMOC1,RGL1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6B,CACNB2,PSD3,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,PFKFB3,TMEFF2,PRRX1,TENM4,MICAL2,ATRNL1,VCAN,NOS1AP,SYTL2,TUBB2B,PTCH1,MAGI2,KCNH1,SV2A,SRGAP3,NAV2,TMEM255A,LPAR6" Coexpression Atlas PCBC_MESO-5_fibroblast_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 3.55E-08 1.58E-04 3.49E-07 3.13E-06 71 985 "TMEM74,SYNDIG1,ADGRV1,CSMD3,ADCY2,RXRG,GALNT13,FABP7,SORCS1,ADORA1,UNC79,C1orf61,PDZD4,SH3GL2,ST8SIA1,SLC1A6,SCG3,SLCO1A2,B3GAT1,SOX10,SALL3,NFASC,FGF17,NODAL,MYRF,GPM6A,GPM6B,NPPA,CECR2,GRIK3,ADAMTS8,CCKBR,PTPN5,LEFTY2,USP2,PAX6,PCDH8,CDH8,SEZ6L,PCSK2,CA14,CHGA,PLEKHB1,DLGAP3,SEMA5B,A2ML1,FAM181B,COL9A2,PACSIN1,ETNPPL,TENM4,KCNT2,NCAN,FMN2,RAB39A,PLPP4,ARHGEF4,ANKS1B,ZNF385B,CADM2,SHD,PTPRD,KCNH1,KCNQ2,HS3ST4,SLC25A48,CALN1,SLC25A18,DSCAM,USH1C,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.40E-08 1.96E-04 4.32E-07 3.88E-06 23 167 "EYA1,SORCS1,SCN3A,SGIP1,DACH2,CADPS,SNAP25,SCN3B,DNER,NAP1L2,C11orf87,ACSL6,BRSK2,CDH10,DCLK1,CNTN1,PRRX1,NRSN1,MAPK10,JAKMIP2,RET,ST8SIA3,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.18E-08 2.30E-04 5.07E-07 4.55E-06 37 377 "PRR5L,EYA1,SORCS1,SCN3A,SGIP1,NTNG1,CACHD1,ZNF365,MIER1,DACH2,CADPS,TNIK,SALL3,NPAS3,GNG4,UNC5D,ADGRL3,TCF7L2,B4GALNT4,DDR2,GRIA2,GRM3,DCLK1,CELF5,SLC25A27,PRRX1,VCAN,FMN2,TOX,LRRTM3,LRP8,CEP170,MAGI2,KCNA4,NTM,TMEM255A,CACNG7" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 Gudmap RNAseq 5.27E-08 2.34E-04 5.14E-07 4.62E-06 17 95 "MAP6,ADGRV1,RTN1,FABP7,TUBB4A,SLIT1,GPM6A,CAMK2A,CELF3,JAM2,ARHGAP22,FEZ1,CTNND2,DPYSL5,KCNK1,NKAIN1,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.61E-08 2.49E-04 5.47E-07 4.91E-06 36 362 "MEG3,EYA1,NDRG2,FABP7,GRAMD1B,NTNG1,PKNOX2,SORCS3,TMEM108,PALLD,NCAM1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6A,GPM6B,GRIA4,GUCY1A2,GUCY1A1,REPS2,PCDH9,LGI1,PDE1A,HPSE2,TMEFF2,PRRX1,FAT3,SNCAIP,TENM4,MICAL2,VCAN,MASP1,LRRTM3,PTCH1,TMEM255A" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 5.81E-08 2.58E-04 5.65E-07 5.07E-06 18 107 "ACTN2,ADCYAP1R1,SLC1A2,BCO1,SLCO1A2,DLL3,ATP1A3,CACNA1A,GRIK4,PRMT8,HPCA,PLCH2,MASP1,LRP8,KCNN3,RFX4,EFNA3,PRRT4" Coexpression Atlas PCBC_MESO-5_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 6.08E-08 2.70E-04 5.90E-07 5.30E-06 70 979 "TMEM74,ADGRV1,CSMD3,ADCY2,RXRG,SORCS1,UNC79,MOBP,C1orf61,PDZD4,SH3GL2,SLC1A6,MSR1,MT3,SCG3,DDX25,B3GAT1,SOX10,SALL3,LHFPL4,NFASC,FGF17,AJAP1,NODAL,MYRF,GPM6A,GPM6B,CECR2,GRIK3,ADAMTS8,CCKBR,PTPN5,LEFTY2,USP2,PAX6,PADI2,PCDH8,CDH8,SEZ6L,CA14,PLEKHB1,SEMA5B,A2ML1,SULT4A1,COL9A2,PACSIN1,ETNPPL,KCNT2,FMN2,PLPP4,ARHGEF4,RIMS3,ANKS1B,DNAJC6,CADM2,ELMO1,SHD,PTPRD,KCNH1,ARNT2,KCNQ2,HS3ST4,SLC25A48,CALN1,DPP6,DSCAM,USH1C,FAM135B,ELAVL4,RCAN2" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k5 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.22E-08 2.76E-04 6.02E-07 5.40E-06 12 46 "ADCY2,DACH2,CADPS,DKK3,NCAM1,ANO4,VWC2,TMEFF2,NEGR1,CNTN1,KCND3,EPB41L2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.80E-08 3.02E-04 6.55E-07 5.88E-06 11 38 "ABAT,ASCL1,TAGLN3,DLL3,NEUROD1,NHLH1,TCF12,CRB1,POU3F2,PANTR1,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 6.80E-08 3.02E-04 6.55E-07 5.88E-06 11 38 "ABAT,ASCL1,TAGLN3,DLL3,NEUROD1,NHLH1,TCF12,CRB1,POU3F2,PANTR1,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.12E-08 3.61E-04 7.81E-07 7.01E-06 25 200 "LGR4,MEG3,ADCY2,PNMA8B,TUBB4A,RASA3,LRRC4C,TMEM108,ZCCHC24,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,PSD3,GUCY1A2,REPS2,DCLK1,PDE1A,PRRX1,TENM4,ATRNL1,PTPRD,SV2A,SRGAP3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.25E-08 3.66E-04 7.91E-07 7.10E-06 15 76 "RTN1,ANK2,ANK3,NSG2,SNAP25,SCN3B,LMO3,SYT4,GNG4,DNAJC12,CELF5,BDNF-AS,SLC17A6,ELAVL3,RCAN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 8.57E-08 3.81E-04 8.20E-07 7.37E-06 14 66 "MAP6,RTN1,SCG3,TAGLN3,NCAM1,GFRA1,SYT4,GNG3,CNTN2,INA,STMN4,SLC17A6,RGS10,ELAVL3" Coexpression Atlas PCBC_ratio_Sex-Associated_Pluripotency-Differentiation-2X-p05 Sex-Associated_Pluripotency-Differentiation-fold2.0_adjp0.05 PCBC_AltAnalyze 8.87E-08 3.94E-04 8.47E-07 7.60E-06 48 574 "MAP6,ASIC1,SYT9,DUSP27,CEND1,MEG3,PNMA8B,FOXG1,C1orf61,PDZD4,SGIP1,BCAN,TAGLN3,DLL3,MYT1L,SOX5,LMO3,ALDH1L1,FGF17,AJAP1,SYT4,DCLK2,GNG3,NODAL,ZEB1,GRID1,GRIK2,CCKBR,PCDH8,SEZ6L,PDE1C,CHGA,CELF5,NECAB2,BTBD17,POU3F4,NCAN,CALY,MAPK10,ELMO1,HS3ST4,TMEM255A,DPP6,FAM135B,PHC2,ZNF248,LPAR6,EN2" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500 Gudmap RNAseq 9.58E-08 4.25E-04 9.13E-07 8.19E-06 96 1522 "DPF1,EPS8,RIMKLA,MEG3,ADCY2,WAC,FABP7,SORCS1,LRRTM4,FHL1,ELMOD1,PDZD4,SGIP1,ANK2,DOCK10,NTNG1,CCDC80,CACHD1,NLGN1,ARHGAP5,CCDC88A,PDE8B,GPR153,SLIT1,ASTN1,RCOR3,TMEM151A,PALLD,DKK3,SCN3B,MYBPC1,TNIK,ZCCHC24,MYH7,ADGRB2,RAP1GAP2,NCAM1,COLGALT2,NDUFA5,INKA2,NELL1,RGL1,NFIA,C1QC,ADGRL3,KLHL4,GPM6A,GPM6B,GPR19,DDR2,PSD3,GRIA4,TIE1,GUCY1A1,DAAM2,CDK11B,DCLK1,PDE1A,PRMT8,TMEFF2,JAM2,SEMA5B,NEGR1,PRRX1,SLC36A4,FAT3,CNRIP1,SNCAIP,TENM4,NKAIN4,KCNT2,FEZ1,VCAN,PROX1,MASP1,BRINP3,TOX,SYTL2,LRRTM3,PMEPA1,LRP8,PTPRD,KCNA6,PTPRE,KCNC1,PTPRZ1,NTM,RABGAP1L,CCDC3,PYGM,FAM13C,BEND5,ABCC9,RGS10,SSPN,VWA5A" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.00E-07 4.44E-04 9.52E-07 8.54E-06 60 798 "ABAT,LGR4,MEG3,F3,ADCY2,FABP7,PNMA8B,TUBB4A,SOX6,RASA3,SESN3,NTNG1,CCDC80,CACHD1,LRRC4C,ST8SIA1,PKNOX2,SCMH1,PDE8B,DDX25,MTR,TMEM108,PALLD,TNIK,ZCCHC24,NEK6,NPAS3,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,PSD3,GUCY1A2,GUCY1A1,DAAM2,REPS2,PCDH9,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,CHRM4,FTO,PRRX1,FAT3,TENM4,MICAL2,ATRNL1,VCAN,PLD5,MAGI2,SV2A,SRGAP3,NAV2,TMEM255A,EPB41L1" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K2 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.08E-07 4.80E-04 1.03E-06 9.21E-06 37 388 "LGR4,ERMN,NLGN4X,LRRTM4,DISP3,SEMA6A,UNC79,PDZD4,TRIM46,USP28,BCAN,CACHD1,SHTN1,TMEM108,CCDC181,SALL3,AJAP1,PTBP2,PLEKHB1,DLGAP3,GDAP1L1,CAMKV,CCDC136,CELF5,BTBD17,POU3F4,ANKS1B,RGMA,SNX27,NKAIN1,FAM57B,DPP6,VANGL2,SEC61A2,CACNG7,RPRD1A,SLC4A10" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.13E-07 5.01E-04 1.07E-06 9.59E-06 39 422 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,CAMK2A,GRIA1,ATP13A2,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,PEX5,DLG2,RALGDS,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.24E-07 5.51E-04 1.17E-06 1.05E-05 22 163 "SLITRK1,LRRTM4,ASRGL1,SHTN1,SLC1A2,DLL3,ATP2B2,SOX5,RHBDL3,ASTN2,SEMA4A,ACSL6,DIRAS1,CAMK2A,PSD3,TUB,CELF5,ATCAY,IGSF1,MAPK10,BRINP3,DTNA" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K1 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.28E-07 5.67E-04 1.20E-06 1.08E-05 44 510 "EPS8,ACTN2,ADCY2,MOBP,SGIP1,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,DKK3,TNIK,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,ATP13A2,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,PMEPA1,CADM2,LRP8,KCNA6,CCDC3,PCDH15,PEX5,DLG2,RALGDS,PRRT4,EPB41L1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.33E-07 5.92E-04 1.25E-06 1.12E-05 12 49 "ADGRV1,ATP2B2,GRIK2,CELF3,GDAP1L1,NRXN2,ATCAY,IGSF1,MAPK10,HES5,STMN4,ELAVL3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.33E-07 5.92E-04 1.25E-06 1.12E-05 12 49 "RTN1,SLC7A14,SNAP25,SCN3B,DNER,C11orf87,INA,CNTN1,MAPK10,DNAJC6,RET,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.35E-07 6.01E-04 1.27E-06 1.14E-05 41 459 "EPS8,ACTN2,ADCY2,MOBP,SEMA6C,SGIP1,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,DKK3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,CAMK2A,GRIA1,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,PMEPA1,CADM2,LRP8,KCNA6,CCDC3,PCDH15,DLG2,RALGDS,PRRT4" Coexpression Atlas ratio_SC_vs_ECTO_500_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 1.42E-07 6.29E-04 1.33E-06 1.19E-05 33 327 "RIMKLA,ADCY2,HPCAL4,PDZD4,BCAN,SCG3,SNCB,MEGF11,JPH4,KLHL4,TMEM151B,SYT6,ADAMTS8,ZDHHC22,C1orf94,DCLK1,HRH3,CHGA,GDAP1L1,CAMKV,RIMS4,LRRTM3,NTM,RABGAP1L,KCNQ2,SLC25A48,CALN1,RET,ST8SIA3,FGFBP3,LINC00599,C2orf80,SEZ6" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k4 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.42E-07 6.33E-04 1.33E-06 1.19E-05 16 90 "RTN1,SCN3A,DACH2,SNAP25,SCN3B,DNER,C11orf87,CLASP2,NFIA,GNG4,DDR2,RBFOX2,PIRT,CNTN1,PRRX1,MAPK10" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.48E-07 6.57E-04 1.38E-06 1.24E-05 58 769 "EPS8,ACER3,LGR4,MEG3,EYA1,ADCY2,FABP7,PNMA8B,GRAMD1B,SOX6,DOCK10,GAS7,GPAM,PKNOX2,CADPS,ARFGAP1,FYN,PALLD,TNIK,ZCCHC24,NCAM1,SMOC1,NFIA,PCDH11X,ADGRL3,KLHL4,GPM6A,GPM6B,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,REPS2,TNS1,PCDH9,PDE1A,ADGRG1,TMEFF2,SERPINE2,ANLN,FAT3,TENM4,MICAL2,ATRNL1,VCAN,DOCK7,DZIP3,MASP1,PTCH1,PTPRD,KCNH1,SRGAP3,PYGM,TMEM255A,DTNA,RAVER2,EPB41L2" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_500 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500 PCBC 1.55E-07 6.89E-04 1.44E-06 1.29E-05 43 496 "RIMKLA,ADCY2,HPCAL4,PDZD4,BCAN,CGREF1,SCG3,SNCB,ATP1A3,MEGF11,TNIK,JPH4,ALDH1L1,ACSBG1,KLHL4,TMEM151B,SYT6,ADAMTS8,MFSD2A,ZDHHC22,C1orf94,DCLK1,HRH3,CHGA,GDAP1L1,CAMKV,ST8SIA5,RIMS4,LRRTM3,PMEPA1,NTM,RABGAP1L,KCNQ2,SLC25A48,CALN1,RET,ST8SIA3,EEF1A2,FGFBP3,LINC00599,C2orf80,RASGRP2,SEZ6" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_250 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_250 FaceBase_ST1 1.60E-07 7.09E-04 1.48E-06 1.33E-05 21 152 "SDE2,FABP7,MT3,CCDC88A,ASCL1,SCG3,PHYHIPL,NKX6-2,FGF17,MFSD2A,PAX6,JAM2,FAM181B,POU3F4,FEZ1,HES5,ZBTB16,TUBB2B,JAKMIP2,ELAVL3,EN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.62E-07 7.21E-04 1.50E-06 1.35E-05 34 345 "TTYH1,WLS,DRAXIN,SCN3A,LINC00461,C1orf61,TAGLN3,PALLD,DNER,NPAS3,NFIA,GPM6B,ZEB1,TCF12,PAX6,PCDH9,PDE1A,ADGRG1,NECAB2,SLC36A4,CNRIP1,POU3F2,CRMP1,NKAIN4,MAPK10,KIAA0408,MASP1,TUBB2B,PRDM2,OLFM3,KCNQ2,TMEM255A,RFX4,ELAVL3" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.72E-07 7.66E-04 1.59E-06 1.43E-05 38 412 "SYNDIG1,MRVI1,ADCY2,CCDC80,DGKD,ST8SIA1,MSR1,DACH2,CADPS,DKK3,ADGRB2,NCAM1,NFIA,CAMSAP2,ANO4,VWC2,GRIA1,GRIA4,GUCY1A1,PCDH8,PCDH9,RBFOX2,TMEFF2,NEGR1,CNTN1,PRRX1,CNRIP1,NKAIN4,ATRNL1,VCAN,SPIRE1,TUBB2B,PTPRO,KCND3,NTM,ZYG11B,EPB41L2,RASGRP2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.73E-07 7.70E-04 1.60E-06 1.43E-05 39 429 "EPS8,PRR5L,EYA1,GALNT13,SORCS1,SCN3A,LRRTM4,SGIP1,NTNG1,ZNF365,SLC14A1,DACH2,CADPS,SON,DNER,NAP1L2,NPAS3,UNC5D,ADGRL3,TBX15,DDR2,PSD3,GRIA2,ZFP91,PCDH8,DCLK1,NLGN3,NEGR1,PRRX1,MAPK8,TOX,LRRTM3,MAGI2,KCNA4,NTM,TMEM255A,PARP11,FAM13C,CBLN2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K1 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.81E-07 8.05E-04 1.67E-06 1.50E-05 41 464 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,DKK3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,GRIK4,OPCML,TMEM25,REPS2,HPSE2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,CCDC3,PCDH15,PEX5,DLG2,RALGDS,PRRT4" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500 facebase_RNAseq_e10.5_Emin_LatNas_2500 Gudmap RNAseq 1.84E-07 8.16E-04 1.69E-06 1.51E-05 92 1459 "DPF1,TTYH1,MAP6,RIMKLA,ACLY,CEND1,ADGRV1,ARID1A,CLIP1,RTN1,WAC,FABP7,TUBB4A,SEMA6A,FHL1,SOX6,SFPQ,ANK2,PPM1E,APC,ZCCHC17,ST3GAL3,ST8SIA1,USP16,RUFY2,PKNOX2,ARHGAP5,YPEL4,CCDC88A,SHANK2,TAGLN3,ASTN1,SMARCE1,SNAP25,ATM,PHYHIPL,SOX5,GART,NASP,INKA2,SEPT3,ACSBG1,GNG3,WSCD1,GPM6A,GPM6B,CACNB2,ZEB1,CLEC9A,TCF12,NRDC,PTBP2,CECR2,GRIK2,USP2,MFSD2A,GUCY1A2,CELF3,CDK11B,TPM3,TPM4,PDE3B,CA14,JAM2,KIAA1549L,ANLN,BTF3L4,NSD2,CRMP1,CRLS1,KCNT2,FEZ1,DOCK7,DZIP3,MAPK8,FGFR1OP2,ZBTB16,TOX,ANKS1B,SPIRE1,TUBB2B,LRP8,KCNC1,PTPRZ1,NKAIN1,KIF2A,DTNA,SFXN5,LMO1,ELAVL4,PLEKHO1,EPB41" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.90E-07 8.43E-04 1.74E-06 1.56E-05 60 813 "PRR5L,EMID1,MBP,F3,SLITRK1,SORCS1,FOXRED2,SCN3A,SCN4B,SEMA6A,BCAR3,SOX6,SH3GL2,AQP4,PDE8B,SPHKAP,KIF21B,MYH7,STARD10,RAP1GAP2,GFRA1,KIRREL3,UNC5D,WWC1,CNDP1,WSCD1,B4GALNT4,AKNA,GRIK2,GRIK4,MFSD2A,PADI2,MAGI1,PRMT8,CA14,PFKFB3,KIAA1549L,SEMA5B,FADS2,MEAF6,NSD2,SF1,PLCH2,PHACTR3,FMN2,CTNND2,TOX,DPYSL5,LRP8,SMG7,PTPRZ1,KCNK1,NAV2,NKAIN1,SUSD4,L1CAM,CAMK1G,RET,VANGL2,C2orf80" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 Gudmap RNAseq 2.08E-07 9.23E-04 1.90E-06 1.70E-05 17 104 "TTYH1,MAP6,ADGRV1,RTN1,FABP7,TUBB4A,SNAP25,INKA2,GPM6A,GPM6B,GRIK2,GUCY1A2,CELF3,JAM2,ZBTB16,LRP8,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.40E-07 1.07E-03 2.19E-06 1.97E-05 61 838 "IL17D,MRVI1,ADD3,BCAR3,ELMOD1,ASRGL1,SGIP1,DOCK10,ZNF365,SLC1A6,SLC14A1,SPHKAP,DKK3,JPH4,NEK6,ADGRB2,NAP1L2,NPAS3,NASP,SPART,C11orf87,CLASP2,NFIA,PCDH11X,MYRF,ANO4,GPM6B,B4GALNT4,DDR2,GUCY1A1,NEURL1,PCDH8,CDH10,RBFOX2,ARHGAP19,MAGI1,PDE1A,PDE4B,PFKFB3,ZBED5,TMEFF2,NEGR1,NMT2,MICAL1,TENM4,FEZ2,VCAN,EDRF1,GON4L,PLPPR5,ITGAV,BLOC1S6,NTM,AK5,KCNK2,DNM2,GOPC,FAM13C,TTLL7,ELAVL4,EPB41L2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 2.70E-07 1.20E-03 2.46E-06 2.21E-05 14 72 "RTN1,ANK3,NSG2,SCN3B,NCAM1,GFRA1,SEPT3,GPM6B,INA,CELF3,NEGR1,PLEKHB2,RET,ELAVL3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.79E-07 1.24E-03 2.53E-06 2.27E-05 9 27 "EYA1,RTN1,FABP7,CADPS,SCG3,SCN3B,INA,TMEFF2,STMN4" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500 FaceBase_RNAseq 3.10E-07 1.38E-03 2.81E-06 2.52E-05 42 491 "MBP,LGR4,ADGRV1,EYA1,IL17D,ERMN,LINC00461,FOXG1,SHTN1,ASCL1,PHYHIPL,ILDR2,GAD2,NMNAT2,STARD10,SMOC1,FGF17,WWC1,WSCD1,HAP1,CECR2,PAX6,TPD52,ADGRG1,CA14,CADM1,TJP2,NECAB2,OSBPL3,HES5,ZBTB16,DPYSL5,PSMD13,KCNK1,NAV2,DLG3,SUSD4,DTNA,RFX4,RAVER2,ELAVL4,EPB41" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_500_1 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_500_1 FaceBase_ST1 3.22E-07 1.43E-03 2.91E-06 2.61E-05 20 145 "SDE2,FABP7,MT3,CCDC88A,ASCL1,SCG3,PHYHIPL,NKX6-2,FGF17,MFSD2A,PAX6,JAM2,FAM181B,POU3F4,HES5,ZBTB16,TUBB2B,JAKMIP2,ELAVL3,EN2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.24E-07 1.44E-03 2.93E-06 2.63E-05 49 618 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,GAS7,SLC1A2,BCO1,SLC6A9,PDE8B,SLCO1A2,DLL3,ADGRA1,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,GOLGB1,TMEM136,CAMK2A,GRIA1,OPCML,TMEM25,LEFTY2,REPS2,PDE4B,NXPH1,MICAL2,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,DLG2,RAB3IL1,PID1,RALGDS,PRRT4,RASGRP2,SEZ6" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.34E-07 1.48E-03 3.01E-06 2.70E-05 36 389 "LGR4,MEG3,ADCY2,FABP7,KIAA1109,RASA3,SESN3,CCDC80,LRRC4C,ST8SIA1,MTR,PALLD,NCAM1,SMOC1,NELL1,NFIA,PCDH11X,MYRF,ADGRL3,PSD3,GUCY1A2,GUCY1A1,DAAM2,REPS2,CDH10,DCLK1,MAGI1,PDE1A,PRRX1,TENM4,ATRNL1,VCAN,MAGI2,SV2A,SRGAP3,TMEM255A" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 200 GSE76381_ESMoleculeCountsPMLog2 3.59E-07 1.59E-03 3.23E-06 2.90E-05 69 1006 "TTYH1,LGR4,ADGRV1,WLS,F3,SLC44A5,DRAXIN,SCN3A,LINC00461,C1orf61,CCDC80,CACHD1,CADPS,TAGLN3,CCDC181,ATP1A2,PALLD,ENKUR,SALL3,DNER,NPAS3,MIR100HG,SLCO1C1,NFIA,CNTN2,ADGRL3,GOLGB1,ANO4,GPM6B,ZEB1,TCF12,NUCB1,PAX6,PCDH9,SEZ6L,ZNF384,PDE1A,PDE4B,ADGRG1,CA14,FAM181B,COL9A2,PRRX1,NECAB2,SLC36A4,CNRIP1,CP,POU3F2,CRMP1,NKAIN4,VCAN,DOCK7,MAPK10,KIAA0408,MASP1,TUBB2B,ITGAV,PMEPA1,PRDM2,OLFM3,KCNK1,KCNQ2,WIPF2,TMEM255A,FAM13C,RFX4,SSPN,ELAVL3,RPE65" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K0 facebase_RNAseq_e10.5_Emin_MedNas_2500_K0 Gudmap RNAseq 3.63E-07 1.61E-03 3.26E-06 2.93E-05 17 108 "TTYH1,MAP6,ADGRV1,FABP7,SNAP25,INKA2,WSCD1,CAMK2A,CECR2,GRIK2,CELF3,CA14,JAM2,FEZ1,ZBTB16,DPYSL5,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.78E-07 1.68E-03 3.39E-06 3.04E-05 36 391 "PRR5L,EYA1,SCN3A,SGIP1,APC,NTNG1,MIER1,DACH2,CADPS,DKK3,ILDR2,NPAS3,CLASP2,NFIA,GNG4,UNC5D,ADGRL3,DDR2,GRIA2,GRM3,ZFP91,PAH,DCLK1,RBFOX2,SLC25A27,PRRX1,VCAN,FMN2,TOX,MAGI2,KCNA4,PTPRO,PTPRZ1,NTM,FAM13C,NUP214" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 3.93E-07 1.75E-03 3.51E-06 3.15E-05 44 531 "EPS8,ACTN2,ADCY2,MOBP,SGIP1,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,DKK3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,OPCML,TMEM25,REPS2,PIRT,COL9A2,NXPH1,PLCH2,MASP1,ZNF385B,PMEPA1,CADM2,LRP8,KCNA6,CCDC3,PCDH15,DLG2,RALGDS,RAP1GAP,SSPN,PRRT4,EPB41L1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 3.97E-07 1.77E-03 3.54E-06 3.18E-05 9 28 "EYA1,FABP7,SCG3,SNAP25,SCN3B,INA,MAPK10,DLG2,ELAVL4" Coexpression Atlas Arv_EB-LF_1000_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 4.17E-07 1.85E-03 3.71E-06 3.33E-05 24 203 "CSMD2,FABP7,ERMN,NLGN4X,PDZD4,CCDC80,SCG3,B3GAT1,TMEM151B,GRIA1,GRIA4,PRRX1,FAT3,BTBD17,KCNT2,RIMS4,FMN2,PLD5,KCNMA1,KCNQ2,FAM57B,LINC00599,C2orf80,SEZ6" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.18E-07 1.86E-03 3.71E-06 3.33E-05 55 736 "SERPINA3,MBP,MRVI1,NDRG2,CLIP1,FGF1,FHL1,ANK1,PI16,SH3GL2,APC,SORBS1,BCAS1,SLC14A1,SNAP25,ATP1A2,PHYHIPL,DKK3,ILDR2,DNER,NFIA,POPDC3,SEMA4A,PRUNE2,GPM6A,DDR2,TF,TNS1,PLEKHB1,CCSER2,MFSD4A,CP,OSBPL3,PLCH2,PRKAB2,CTNND2,ZBTB16,SYTL2,DNAJC6,PTHLH,KCNA1,KCND3,PTPRZ1,RABGAP1L,CCDC3,KCNK1,KCNMA1,PLEKHB2,FAM13C,DTNA,ABCC9,TTLL7,SSPN,LMO1,RCAN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.36E-07 1.94E-03 3.86E-06 3.47E-05 22 175 "PRR5L,EYA1,SORCS1,SCN3A,LRRTM4,SGIP1,SLC14A1,DACH2,DNER,NAP1L2,NPAS3,UNC5D,ADGRL3,TBX15,GRIA2,PCDH8,DCLK1,PRRX1,TOX,KCNA4,TMEM255A,CBLN2" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.51E-07 2.00E-03 3.99E-06 3.58E-05 15 86 "ADCY2,DACH2,CADPS,DKK3,NCAM1,CAMSAP2,ANO4,VWC2,PCDH8,TMEFF2,NEGR1,CNTN1,PTPRO,KCND3,EPB41L2" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_100 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_100 FaceBase_RNAseq 4.79E-07 2.13E-03 4.23E-06 3.80E-05 16 98 "ADGRV1,ZCCHC17,PHYHIPL,ILDR2,FGF17,AJAP1,WWC1,CECR2,INA,FAM181B,HES5,ZBTB16,DPYSL5,NAV2,ST8SIA3,RFX4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 4.82E-07 2.14E-03 4.25E-06 3.82E-05 37 412 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,TMEM136,GRIA1,ATP13A2,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,PEX5,DLG2,RALGDS,PRRT4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K4 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 5.00E-07 2.22E-03 4.40E-06 3.95E-05 24 205 "ACTN2,ADCY2,MOBP,SH3GL2,DOCK10,SLC1A2,ATP1A3,ARPP21,ADGRB2,C11orf87,C1QC,TMEM25,REPS2,NXPH1,MASP1,ZNF385B,CADM2,LRP8,KCNA6,CCDC3,PCDH15,DLG2,RALGDS,PRRT4" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K1 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 5.12E-07 2.27E-03 4.49E-06 4.03E-05 40 465 "EPS8,ACTN2,ADCY2,HPCAL4,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,ATP13A2,OPCML,TMEM25,REPS2,TNS1,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,PEX5,DLG2,RALGDS,PRRT4" Coexpression Atlas ratio_SC_vs_DE_500_K2 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 5.43E-07 2.41E-03 4.76E-06 4.27E-05 14 76 "SCN4B,ATP1A2,ATP1A3,CPLX2,ALDH1L1,SLCO1C1,ABCC8,TNFRSF1B,ST8SIA5,CABP1,SLC45A1,PYGM,SUSD4,ARHGEF10L" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 5.75E-07 2.55E-03 5.03E-06 4.51E-05 18 124 "FHL1,ZCCHC17,SCG3,PHYHIPL,ILDR2,NASP,WWC1,GPR19,PRMT8,NRXN2,SEMA5B,FLRT1,FAM181B,KCNT2,CTNND2,JAKMIP2,RFX4,LRRC23" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K1 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 6.08E-07 2.70E-03 5.30E-06 4.76E-05 62 881 "EPS8,ACTN2,ADCY2,TESK2,MOBP,SGIP1,SH3GL2,DOCK10,NTNG1,SLC1A2,MSR1,SLC6A9,PDE8B,DLL3,TMEM151A,ATP1A3,DKK3,ARPP21,CPLX2,ADGRB2,C11orf87,NELL1,ACSBG1,NFIA,C1QC,KAZN,GNG4,UNC5D,ADGRL3,TMEM136,TBX15,CLEC9A,NRGN,GRIA1,GRIK4,OPCML,TMEM25,REPS2,PIRT,COL9A2,PRRX1,NXPH1,CRLS1,SNCAIP,ATRNL1,PLCH2,MASP1,ZNF385B,PMEPA1,CADM2,KCNA6,CCDC3,PCDH15,DLG2,RALGDS,RAP1GAP,BEND5,ABCC9,SSPN,VWA5A,PRRT4,EPB41L1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_100 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_100 FaceBase_ST1 6.41E-07 2.85E-03 5.59E-06 5.02E-05 14 77 "TTYH1,FABP7,LINC00461,SCG3,CSPG5,NPAS3,NEUROD1,GPM6A,MFSD2A,PAX6,JAM2,FAM181B,FEZ1,TUBB2B" Coexpression Atlas JC_iEC_2500_K2 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 6.69E-07 2.97E-03 5.81E-06 5.22E-05 31 317 "LGR4,ADCY2,GALNT13,RYR1,ITSN1,SH3GL2,PPM1E,SLC1A6,SLC8A2,SLCO1A2,TMEM108,SNCB,NMNAT2,RHBDL3,PCDH11X,GNG4,TCF7L2,HAP1,SYT6,ZDHHC22,DCLK1,TUB,CRMP1,PRKCG,LRRTM3,PTPRD,PTPRZ1,PCDH15,RET,RGS7,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K3 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 6.73E-07 2.99E-03 5.84E-06 5.25E-05 38 435 "EPS8,ACTN2,MOBP,SH3GL2,GAS7,SLC1A2,BCO1,SLC6A9,PDE8B,SLCO1A2,DLL3,ATP1A3,ARPP21,C11orf87,ACSBG1,GNG4,CAMK2A,GRIA1,OPCML,TMEM25,REPS2,PDE4B,NXPH1,MICAL2,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,DLG2,RAB3IL1,PID1,PRRT4,RASGRP2,SEZ6" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k5_500 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.29E-07 3.24E-03 6.32E-06 5.67E-05 11 47 "MAPT,FABP7,LINC00461,TAGLN3,DLL3,INA,CRMP1,TUBB2B,RFX4,VANGL2,ELAVL4" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.65E-07 3.40E-03 6.61E-06 5.93E-05 59 828 "LGR4,ADCY2,ADCYAP1R1,FABP7,SEMA6A,SOX6,RASA3,DOCK10,CCDC80,GPAM,CACHD1,LRRC4C,ST8SIA1,PKNOX2,ARFGAP1,MTR,SMARCE1,PALLD,MYBPC1,ZCCHC24,NCAM1,SMOC1,RGL1,SEPT3,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,GPM6B,B4GALNT4,PSD3,TGFBR3,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,ARHGAP19,MAGI1,PDE1A,HMGB1,TMEFF2,ANLN,PRRX1,FAT3,PPP2R5C,TENM4,MICAL2,ATRNL1,VCAN,SYTL2,PTCH1,MAGI2,PTPRD,SV2A,SRGAP3,TMEM255A,PLEKHO1" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4 Gudmap RNAseq 7.94E-07 3.53E-03 6.85E-06 6.15E-05 75 1151 "DPF1,SERPINA3,EXTL1,MEG3,NDRG2,GRAMD1B,LRRTM4,SEMA6A,PDZD4,SOX6,TRIM46,SGIP1,CNIH2,NTNG1,GAS7,NLGN1,ST8SIA1,KIAA1614,RUFY2,CCDC88A,GPR153,SLIT1,TAGLN3,ASTN1,SNAP25,TMEM151A,NRG3,PHYHIPL,PALLD,DKK3,MYBPC1,TNIK,SOX5,KIF21B,CADM3,ADGRB2,NCAM1,NELL1,NFIA,ADGRL3,DDR2,PSD3,GRIA4,TF,REPS2,DCLK1,NLGN3,CADM1,NRXN1,NEGR1,CPT1C,CCDC136,MICAL1,SLC36A4,CNRIP1,SNCAIP,TENM4,KCNT2,CSF3R,ATRNL1,VCAN,MASP1,BRINP3,TOX,LRRTM3,SHD,PTPRD,KCNA6,PTPRE,PTPRZ1,RABGAP1L,BEND5,EFNA3,VWA5A,EPB41L2" Coexpression Atlas Arv_SC-HD_500 AravindRamakr_StemCell-HD_top-relative-expression-ranked_500 PCBC 8.00E-07 3.55E-03 6.87E-06 6.17E-05 41 491 "RIMKLA,ADGRV1,FABP7,NLGN4X,PDZD4,PPM1E,SLC1A6,SCG3,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,PCDH11X,C1QC,SYT6,GRIA4,GRM3,ZDHHC22,IGSF21,C1orf94,CHGA,GDAP1L1,CAMKV,CABP1,CELF5,ATCAY,BTBD17,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,USH1C,FGFBP3,LINC00599,SEZ6" Coexpression Atlas Arv_SC_fibroblast_500 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 8.00E-07 3.55E-03 6.87E-06 6.17E-05 41 491 "RIMKLA,ADGRV1,FABP7,NLGN4X,PDZD4,PPM1E,SLC1A6,SCG3,DDX25,B3GAT1,SNCB,SALL3,LHFPL4,PCDH11X,C1QC,SYT6,GRIA4,GRM3,ZDHHC22,IGSF21,C1orf94,CHGA,GDAP1L1,CAMKV,CABP1,CELF5,ATCAY,BTBD17,KCNT2,RIMS4,RAB39A,IGSF1,RIMS3,CADM2,KCNQ2,NKAIN1,FAM57B,USH1C,FGFBP3,LINC00599,SEZ6" Coexpression Atlas skeletal muscle skeletal muscle Human Protein Atlas 8.19E-07 3.64E-03 7.02E-06 6.31E-05 31 320 "ACHE,DUSP27,ACTN2,IL17D,ADCY2,RXRG,RYR1,HHATL,SEMA6C,ANK1,SLC8A3,SLN,KBTBD12,ATP1A2,MYBPC1,MYH7,POPDC3,TBX15,NEURL1,PADI2,TPM3,IGFN1,FNDC5,BEST3,DUSP26,PHKG1,KCNJ11,PYGM,NKAIN1,EEF1A2,LMO1" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k2_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.28E-07 3.68E-03 7.08E-06 6.36E-05 15 90 "MAPT,ATAT1,FABP7,ASCL1,TAGLN3,DLL3,SNAP25,SOX5,GNG3,INA,CRMP1,TUBB2B,NKAIN1,VANGL2,ELAVL4" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.82E-07 3.92E-03 7.54E-06 6.77E-05 13 68 "FABP7,DRAXIN,LINC00461,NSG2,TAGLN3,SNAP25,DNER,NAP1L2,NEUROD1,PCDH8,DCLK1,CRMP1,ELAVL4" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.94E-07 3.97E-03 7.62E-06 6.84E-05 59 832 "SDE2,ABAT,LGR4,MEG3,F3,ADCY2,FABP7,SEMA6A,RASA3,DOCK10,SESN3,CCDC80,CACHD1,LRRC4C,ST8SIA1,PKNOX2,SCMH1,MTR,SMARCE1,TMEM108,PALLD,MYBPC1,ZCCHC24,NASP,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,GPM6B,B4GALNT4,TCF12,PTBP2,DDR2,PSD3,TGFBR3,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,HMGB1,TMEFF2,PRRX1,FAT3,TENM4,ATRNL1,VCAN,SYTL2,MAGI2,SV2A,SRGAP3,TMEM255A,PLEKHO1" Coexpression Atlas PCBC_MESO-5_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 9.35E-07 4.16E-03 7.95E-06 7.13E-05 41 494 "ADGRV1,CSMD3,RXRG,SORCS1,ADORA1,UNC79,C1orf61,PDZD4,SCG3,B3GAT1,SOX10,FGF17,AJAP1,NODAL,MYRF,GPM6A,GRIK3,CCKBR,PTPN5,LEFTY2,USP2,PCDH8,CDH8,SEZ6L,CA14,PLEKHB1,SEMA5B,A2ML1,COL9A2,PACSIN1,ETNPPL,KCNT2,FMN2,ANKS1B,CADM2,SHD,KCNQ2,SLC25A48,DSCAM,USH1C,ELAVL4" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 9.35E-07 4.16E-03 7.95E-06 7.13E-05 41 494 "ACTN2,EYA1,SLITRK1,LINC00461,HPCAL4,FOXG1,SLC1A2,BCO1,PDE8B,ASTN1,TMEM151A,ATP1A3,ATP2B2,ARPP21,LMO3,PCDH11X,ROBO3,CLEC9A,NRGN,HAP1,CECR2,GRIK2,LEFTY2,MFSD2A,GUCY1A2,PAX6,ADGRG1,HPSE2,PRRX1,SNCAIP,PLCH2,FGFR1OP2,TOX,ZNF385B,JAKMIP2,PMEPA1,STMN4,RAP1GAP,ABCC9,RFX4,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 9.41E-07 4.18E-03 7.97E-06 7.16E-05 10 39 "RTN1,ANK3,NSG2,SCN3B,NCAM1,SEPT3,INA,CELF3,NEGR1,ELAVL3" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.42E-07 4.19E-03 7.97E-06 7.16E-05 38 441 "EPS8,ABAT,GRAMD1B,ADORA1,BCAR3,SEMA6C,SH3GL2,DOCK10,GAS7,ST8SIA1,SHTN1,CADPS,CSPG5,TNIK,FXYD6,SMOC1,NELL1,ADHFE1,GPM6B,PADI2,TPD52,PDE2A,FNDC5,ADGRG1,SERPINE2,FADS2,VCAN,MASP1,PTCH1,JAKMIP2,ELMO1,PTPRE,PLPPR4,KCNH1,SRGAP3,KCNK2,DTNA,SIDT2" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_1000 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000 PCBC 9.83E-07 4.37E-03 8.31E-06 7.46E-05 67 994 "C1orf194,MAP6,EMID1,IL17D,WLS,SLC30A10,SOX6,SESN3,CCDC80,SYBU,BCO1,PKNOX2,TAGLN3,PHYHIPL,SOX5,ILDR2,LMO3,COLGALT2,STOX1,SMOC1,GPR162,KIRREL3,NHLH1,DCLK2,FAM69C,ZEB1,AZIN2,CAMK2A,VXN,GUCY1A1,CELF3,NEURL1,KCNK10,MAEL,PAX6,LGI1,PDE1C,IGFN1,FNDC5,HAPLN2,ADGRG1,COL9A2,POU3F2,PLCH2,KIAA1755,CMTM5,PLPP4,MAPK10,HES5,PROX1,ZBTB16,DPYSL5,ZNF385B,STMN4,KCNA1,OLFM3,CDH20,CCDC3,TMEM255A,CAMK1G,RFX4,ZNF248,RLBP1,SLC4A10,PRRT4,BAALC,ATP6V1G2-DDX39B" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.87E-07 4.38E-03 8.32E-06 7.47E-05 33 356 "ACER3,MEG3,NDRG2,ADCY2,ADCYAP1R1,FABP7,GRAMD1B,GPAM,PKNOX2,ATP1A3,NCAM1,SMOC1,ACSBG1,NFIA,PCDH11X,ADGRL3,GPM6B,GRIA4,TGFBR3,GUCY1A1,REPS2,PCDH9,PDE1A,TMEFF2,SERPINE2,FADS2,FAT3,MICAL2,VCAN,PTCH1,KCND3,TMEM255A,SLC6A15" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.12E-06 4.96E-03 9.40E-06 8.44E-05 33 358 "ABAT,LGR4,MEG3,ADCY2,CCDC80,GPAM,LRRC4C,SCMH1,MTR,PALLD,NPAS3,NCAM1,SMOC1,NELL1,NFIA,PCDH11X,ADGRL3,GPM6B,CACNB2,TCF12,PSD3,GUCY1A1,DAAM2,PCDH9,PDE1A,FNDC5,PRRX1,ATRNL1,VCAN,PLD5,MAGI2,SRGAP3,TMEM255A" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.19E-06 5.27E-03 9.96E-06 8.94E-05 35 393 "IL17D,MRVI1,SCN3A,KIAA1109,SH3GL2,SORBS1,DACH2,CADPS,SCMH1,SORCS3,DKK3,TNIK,KIF1B,NPAS3,SMOC1,NFIA,CAMSAP2,PRUNE2,GPM6B,VWC2,ZFP91,PCDH9,RBFOX2,KIAA1549L,NEGR1,CNTN1,PRRX1,CNRIP1,VCAN,RBPJ,KCND3,RABGAP1L,KCNK2,KCNMA1,EPB41L2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 1.19E-06 5.29E-03 9.98E-06 8.96E-05 29 293 "ACTN2,MOBP,SH3GL2,GAS7,SLC1A2,BCO1,SLCO1A2,DLL3,ATP1A3,ARPP21,C11orf87,ACSBG1,CAMK2A,GRIA1,TMEM25,REPS2,NXPH1,MICAL2,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,KCNA6,PCDH15,DLG2,PRRT4,RASGRP2,SEZ6" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K3 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.31E-06 5.83E-03 1.10E-05 9.85E-05 17 118 "FHL1,PHYHIPL,ILDR2,LMO3,GNG3,TCF7L2,RFFL,CDK11B,PAX6,PRMT8,KIAA1549L,NRXN2,CTNND2,MASP1,JAKMIP2,PTPRZ1,RFX4" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.34E-06 5.96E-03 1.12E-05 1.01E-04 30 311 "MEG3,EYA1,ADCY2,FABP7,PNMA8B,GPAM,PKNOX2,ARFGAP1,PALLD,ZCCHC24,NCAM1,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,REPS2,TNS1,PCDH9,TMEFF2,FAT3,TENM4,MICAL2,ATRNL1,VCAN,PTCH1,PTPRD,PYGM,RAVER2,EPB41L2" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.41E-06 6.28E-03 1.18E-05 1.06E-04 59 844 "MAPT,ACLY,MEG3,ATAT1,ARID1A,WAC,FABP7,FOXM1,SFPQ,ITSN1,SESN3,DGKZ,ASCL1,TAGLN3,DLL3,TMEM108,SNAP25,SON,SOX5,ZCCHC24,NEK6,GART,NASP,SPART,NCAM1,OS9,GNG3,MYRF,BTRC,KLHL4,GPM6B,DDR1,TCF12,CAMK2G,INA,TIE1,TMEM9,CDC42,TNS1,RBFOX2,ZMYND8,UBTF,FADS2,SF1,CRMP1,RNF14,PRKACB,CTNND1,PUM1,TUBB2B,BLOC1S6,PEX5,NKAIN1,KIF2A,RTN4,VANGL2,ELAVL4,PLEKHO1,EPB41L2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.43E-06 6.34E-03 1.19E-05 1.07E-04 37 431 "ABAT,PRR5L,CDHR1,MEG3,EYA1,MRVI1,ST8SIA1,SLC14A1,DACH2,SORCS3,ASTN1,DNER,NCAM1,SYT4,ANO4,DDR2,VSTM2A,GRIA1,GRIA4,GRM3,PCDH8,LGI1,PDE1C,TMEFF2,NEGR1,CNTN1,PRRX1,CRMP1,SNCAIP,LRP8,KCNA1,PTPRO,NTM,CCDC3,DNM2,ABCC9,EFNA3" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.59E-06 7.08E-03 1.32E-05 1.19E-04 37 433 "TTYH1,EPS8,GRAMD1B,ADORA1,BCAR3,SOX6,SEMA6C,USP28,SH3GL2,DOCK10,GAS7,SHTN1,CADPS,FYN,TNIK,SMOC1,ADHFE1,GPM6B,DAAM2,PADI2,TPD52,FNDC5,ADGRG1,JAM2,SERPINE2,FADS2,MASP1,TOX,JAKMIP2,ELMO1,PTPRE,PLPPR4,KCNH1,SRGAP3,GNE,DTNA,SIDT2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.03E-06 9.00E-03 1.68E-05 1.51E-04 34 385 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,TMEM136,GRIA1,OPCML,TMEM25,REPS2,NXPH1,PLCH2,VCAN,MASP1,ZNF385B,CADM2,LRP8,KCNA6,PCDH15,DLG2,RALGDS,PRRT4" Coexpression Atlas GSM605853_500 "Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3" "Immgen.org, GSE15907" 2.10E-06 9.35E-03 1.74E-05 1.56E-04 35 403 "ACER3,FCGR1A,SEMA6A,FGR,SGIP1,ITSN1,CCDC88A,RGL1,C1QC,ADGRL3,TCF7L2,CLEC9A,HAP1,PSD3,ATP13A2,TF,ATG4C,CD81,TNS1,MS4A7,CADM1,ZFYVE9,VAV2,CSF3R,DOCK7,SDC3,CTNND1,KIAA0513,RIMS3,SIRPA,KCNA2,KCNJ10,DLG2,RAB3IL1,PID1" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.16E-06 9.61E-03 1.79E-05 1.60E-04 36 421 "LGR4,ADGRV1,MRVI1,ADCY2,GALNT13,SORCS1,SCN3A,LRRTM4,DOCK10,NTNG1,ST8SIA1,SLCO1A2,DNER,KIRREL3,RHBDL3,PCDH11X,ADGRL3,ANO4,DDR2,GRIA1,GRIA4,GRM3,ZFP91,PCDH8,PDE4B,CADM1,NEGR1,ANLN,ITGAV,NTM,CCDC3,CALN1,FAM13C,CRTAC1,EFNA3,ABI2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.21E-06 9.81E-03 1.82E-05 1.63E-04 15 97 "EYA1,RTN1,FABP7,CADPS,SCG3,TAGLN3,SCN3B,GNG3,INA,HPSE2,TMEFF2,PRRX1,FAT3,STMN4,CACNG7" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_100 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100 FaceBase_RNAseq 2.21E-06 9.81E-03 1.82E-05 1.63E-04 15 97 "APC2,FOXG1,MADD,TMEM151A,ARPP21,PCDH11X,CACNA1A,HAP1,GRIK2,LEFTY2,PAX6,HPSE2,RAP1GAP,L1CAM,ELAVL4" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.28E-06 1.02E-02 1.88E-05 1.68E-04 58 837 "EPS8,ABAT,LGR4,SOX6,SEMA6C,RASA3,DOCK10,GAS7,CACHD1,ST8SIA1,SHTN1,KIAA1614,CADPS,MTR,ATP1A2,FYN,MYBPC1,TNIK,SOX5,GART,SMOC1,RCOR2,NELL1,ADHFE1,NFIA,PCDH11X,OS9,ADGRL3,GPM6B,CDH10,DCLK1,TPD52,MAGI1,PDE2A,FNDC5,ADGRG1,CHRM4,SERPINE2,FADS2,VAV2,FAT3,PPP2R5C,VCAN,CTNND1,NOS1AP,SPIRE1,TUBB2B,LRRTM3,PTCH1,ELMO1,PTPRE,KCNH1,KCNK2,NAV2,DTNA,SIDT2,LPAR6,EPB41L1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k3 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.41E-06 1.07E-02 1.98E-05 1.78E-04 12 63 "MRVI1,SCN3A,DACH2,CADPS,GPM6B,VWC2,NEGR1,CNTN1,PRRX1,CNRIP1,KCND3,EPB41L2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.52E-06 1.12E-02 2.06E-05 1.85E-04 23 209 "EPS8,ACTN2,ADCY2,SH3GL2,SLC1A2,SLC6A9,PDE8B,ARPP21,ADGRB2,NELL1,C1QC,GNG4,UNC5D,CAMK2A,GRIA1,REPS2,NXPH1,MASP1,ZNF385B,CADM2,LRP8,PCDH15,DLG2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.60E-06 1.16E-02 2.13E-05 1.91E-04 31 338 "ADCY2,ADCYAP1R1,FABP7,GPAM,LRRC4C,PKNOX2,ARFGAP1,SMARCE1,PALLD,ZCCHC24,NCAM1,SEPT3,NFIA,MYRF,B4GALNT4,PSD3,TGFBR3,GUCY1A2,GUCY1A1,CDH10,TMEFF2,PRRX1,FAT3,TENM4,MICAL2,ATRNL1,VCAN,SYTL2,PTPRD,SV2A,SRGAP3" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K5 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 2.62E-06 1.16E-02 2.13E-05 1.91E-04 11 53 "MBP,ADGRV1,LINC00461,FOXG1,SHTN1,ASCL1,HAP1,ADGRG1,HES5,DPYSL5,DTNA" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1 Gudmap RNAseq 2.63E-06 1.17E-02 2.14E-05 1.92E-04 74 1168 "DPF1,EPS8,RIMKLA,MEG3,ADCY2,WAC,FABP7,SORCS1,FHL1,ELMOD1,PDZD4,SGIP1,ANK2,NTNG1,CACHD1,NLGN1,ARHGAP5,CCDC88A,GPR153,SLIT1,ASTN1,RCOR3,TMEM151A,PALLD,DKK3,SCN3B,MYBPC1,TNIK,ADGRB2,RAP1GAP2,NCAM1,COLGALT2,NDUFA5,INKA2,NELL1,NFIA,ADGRL3,GPM6A,GPM6B,GPR19,DDR2,PSD3,GRIA4,CDK11B,DCLK1,PRMT8,JAM2,SEMA5B,NEGR1,PRRX1,SLC36A4,FAT3,CNRIP1,SNCAIP,TENM4,NKAIN4,KCNT2,FEZ1,VCAN,PROX1,MASP1,TOX,PMEPA1,LRP8,PTPRD,KCNA6,PTPRE,KCNC1,PTPRZ1,NTM,RABGAP1L,BEND5,RGS10,VWA5A" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.75E-06 1.22E-02 2.23E-05 2.00E-04 33 373 "LGR4,MEG3,FABP7,PNMA8B,RASA3,GPAM,LRRC4C,PKNOX2,PDE8B,MTR,TMEM108,PALLD,NPAS3,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,GUCY1A1,DAAM2,REPS2,PCDH9,DCLK1,MAGI1,PDE1A,FNDC5,PRRX1,ATRNL1,PLD5,MAGI2,SRGAP3,TMEM255A" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.81E-06 1.25E-02 2.28E-05 2.05E-04 20 166 "CDHR1,EYA1,FGF1,AMPH,SGIP1,DACH2,ATP1A2,MYBPC1,FXYD6,NELL1,CECR2,NEGR1,FAT3,NXPH1,SNCAIP,VCAN,PTHLH,ITIH2,DTNA,ELAVL4" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_100 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_100 FaceBase_RNAseq 2.87E-06 1.28E-02 2.32E-05 2.08E-04 15 99 "ADGRV1,ERMN,TUBB4A,ILDR2,SALL3,TTLL9,C11orf87,AJAP1,CECR2,INA,PAX6,DPYSL5,CA10,CDH20,ST8SIA3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.87E-06 1.28E-02 2.32E-05 2.08E-04 12 64 "EYA1,SORCS1,SCN3A,SGIP1,NTNG1,DACH2,CADPS,NAP1L2,NPAS3,GRIA2,NEGR1,LRRTM3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.99E-06 1.33E-02 2.41E-05 2.16E-04 22 196 "EYA1,SORCS1,LRRTM4,SGIP1,NTNG1,DACH2,DNER,NAP1L2,NPAS3,ADGRL3,PTBP2,GRM3,ZFP91,DCLK1,NLGN3,CELF5,PRRX1,TOX,LRRTM3,LRP8,CEP170,KCNK2" Coexpression Atlas PCBC_ECTO_100 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_100 PCBC 3.26E-06 1.45E-02 2.62E-05 2.35E-04 15 100 "FABP7,BCO1,B3GAT1,PHYHIPL,ILDR2,CELF3,KCNK10,PAX6,CDH8,LGI1,POU3F2,HES5,DPYSL5,ZNF385B,OLFM3" Coexpression Atlas PCBC_EB_fibroblast_100 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100 PCBC 3.26E-06 1.45E-02 2.62E-05 2.35E-04 15 100 "NSG2,NELL1,SYT4,CNTN2,GPM6A,TF,CELF3,SCRG1,GDAP1L1,POU3F2,NKAIN4,STMN4,KCNQ2,ELAVL3,ELAVL4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.26E-06 1.45E-02 2.62E-05 2.35E-04 15 100 "ADGRV1,RTN1,ASTN1,WSCD1,PAX6,PCDH9,KIAA1549L,SEMA5B,POU3F4,FEZ1,FMN2,CTNND2,TOX,DPYSL5,NTM" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.32E-06 1.48E-02 2.66E-05 2.39E-04 36 429 "PRR5L,EYA1,SORCS1,TESK2,SCN3A,SGIP1,ZNF365,SLC14A1,DACH2,CADPS,ASPH,ASTN1,SON,DNER,NAP1L2,CAMTA1,GNG4,UNC5D,ADGRL3,TBX15,DDR2,GRIA2,PCDH8,DCLK1,NLGN3,PRRX1,FMN2,TOX,JAKMIP2,MAGI2,KCNA4,PTPRE,NTM,TMEM255A,FAM13C,CBLN2" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.59E-06 1.59E-02 2.87E-05 2.57E-04 28 293 "NDRG2,ADORA1,TUBB4A,LRRC7,FHL1,PPM1E,NTNG1,SLC6A9,CPLX2,ARHGEF7,CACNB2,ADAMTS8,DCLK1,LGI1,PCSK2,HPSE2,CABP1,FAT3,VCAN,PLD5,MAPK10,SYTL2,LRRTM3,NTM,CCDC3,TMEM255A,LMO1,RERGL" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.71E-06 1.65E-02 2.96E-05 2.66E-04 37 449 "EPS8,ACTN2,ADCY2,HPCAL4,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,CADM2,KCNA6,RABGAP1L,CCDC3,PCDH15,DLG2,RALGDS,PRRT4,SEZ6" Coexpression Atlas geo_heart_2500_K2 geo_heart_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 3.78E-06 1.68E-02 3.01E-05 2.70E-04 72 1138 "SERPINA3,RIMKLA,MAPT,ACTN2,FAM43B,ECSIT,KCNIP2,NDRG2,ADORA1,ADORA3,AGT,SCN4B,ANK2,GAS7,TACC2,SORBS1,AQP4,SPHKAP,KBTBD12,ATP1A2,ATP1A3,PALLD,WDTC1,B3GALT2,ZCCHC24,MYH7,B4GALNT1,STARD10,NCAM1,ALDH1L1,GFRA1,ADHFE1,C1QC,TBX15,CACNB2,CAMK2A,PCDHGA3,GRID1,TF,PTPN5,TLL2,DAAM2,TNFRSF1B,TNS1,PDE1A,PDE1C,PDE2A,HAPLN2,CHI3L2,ASIC3,DUSP26,PHKG1,HPR,FLRT1,CABP1,BEST1,PRRX1,CP,ETNPPL,SLC45A1,MASP1,ZBTB16,DKFZp779M0652,KCNJ11,PYGM,RAB3IL1,SLC25A18,SUSD4,ABCC9,EEF1A2,SSPN,RCAN2" Coexpression Atlas geo_heart_500_K3 geo_heart_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 3.83E-06 1.70E-02 3.04E-05 2.73E-04 21 184 "SERPINA3,ACTN2,KCNIP2,AGT,SORBS1,MT3,SPHKAP,KBTBD12,ATP1A3,NCAM1,C1QC,CACNB2,GPR17,CAMK2A,CHI3L2,DUSP26,PHKG1,HPR,PYGM,EEF1A2,RCAN2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.89E-06 1.73E-02 3.09E-05 2.77E-04 14 89 "RTN1,SCN3A,DACH2,CADPS,SNAP25,SCN3B,DNER,C11orf87,GFRA1,CDH10,RBFOX2,PRRX1,MAPK10,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.03E-06 1.79E-02 3.19E-05 2.86E-04 12 66 "LRRTM4,DNER,ADGRL3,TBX15,GRIA2,PCDH8,DCLK1,PRRX1,TOX,KCNA4,TMEM255A,CBLN2" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_200 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.06E-06 1.81E-02 3.21E-05 2.88E-04 20 170 "EPS8,ADORA1,SEMA6C,SH3GL2,GAS7,SHTN1,CADPS,TNIK,SMOC1,GPM6B,DAAM2,ADGRG1,JAM2,SERPINE2,TOX,JAKMIP2,ELMO1,PLPPR4,KCNH1,DTNA" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.48E-06 1.99E-02 3.53E-05 3.17E-04 31 347 "MAP6,ADGRV1,ADD3,FABP7,SFPQ,CCDC80,LRRC4C,ARHGAP5,CADPS,ASCL1,CCDC181,NASP,SPART,RND1,GPM6B,TCF12,PSD3,HMGB1,JAM2,FAT3,NXPH1,POU3F2,SF1,TENM4,HES5,TOX,MAGI2,PANTR1,DTNA,RFX4,EN2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K1 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 4.55E-06 2.02E-02 3.58E-05 3.22E-04 36 435 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,ITGAV,CADM2,LRP8,KCNA6,PCDH15,DLG2,RALGDS,PRRT4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K4 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 4.75E-06 2.11E-02 3.73E-05 3.35E-04 12 67 "RTN1,FOXG1,NTNG1,CCDC80,ASCL1,NFIA,GRIK2,PCDH9,FEZ1,FMN2,TOX,LRP8" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.77E-06 2.12E-02 3.74E-05 3.36E-04 23 217 "PRR5L,EYA1,SCN3A,SGIP1,NTNG1,MIER1,DACH2,CADPS,NPAS3,GNG4,UNC5D,ADGRL3,DDR2,GRIA2,GRM3,DCLK1,SLC25A27,PRRX1,FMN2,TOX,MAGI2,KCNA4,NTM" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.01E-06 2.23E-02 3.93E-05 3.53E-04 35 419 "LGR4,FABP7,RASA3,DOCK10,CCDC80,CACHD1,LRRC4C,ST8SIA1,PKNOX2,PALLD,ZCCHC24,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,GPM6B,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,PDE1A,TMEFF2,PRRX1,FAT3,TENM4,MICAL2,ATRNL1,VCAN,SYTL2,SV2A,TMEM255A" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_500 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.04E-06 2.24E-02 3.94E-05 3.54E-04 36 437 "LGR4,MEG3,F3,FABP7,TUBB4A,RASA3,CCDC80,CACHD1,ST8SIA1,PKNOX2,MTR,TMEM108,PALLD,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,PFKFB3,TMEFF2,PRRX1,TENM4,ATRNL1,VCAN,SYTL2,TMEM255A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.09E-06 2.26E-02 3.97E-05 3.57E-04 14 91 "EYA1,SORCS1,SCN3A,SGIP1,DACH2,CADPS,SNAP25,SCN3B,DNER,C11orf87,CDH10,DCLK1,MAPK10,ELAVL4" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_1000 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.13E-06 2.28E-02 4.00E-05 3.59E-04 13 79 "MEG3,EYA1,FABP7,PNMA8B,GRAMD1B,SOX6,PSRC1,FADS2,MICAL2,VCAN,MASP1,PTCH1,PTPRD" Coexpression Atlas ratio_ECTO_vs_SC_500_K1 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 5.49E-06 2.44E-02 4.27E-05 3.83E-04 27 283 "MAP6,WLS,SLC30A10,BCO1,TAGLN3,PHYHIPL,SOX5,ILDR2,COLGALT2,STOX1,SMOC1,GPR162,NHLH1,CELF3,KCNK10,PAX6,LGI1,COL9A2,POU3F2,HES5,DPYSL5,ZNF385B,STMN4,KCNA1,OLFM3,RFX4,RLBP1" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K3 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 5.57E-06 2.47E-02 4.32E-05 3.88E-04 35 421 "EPS8,ACTN2,ADCY2,MOBP,SH3GL2,SLC1A2,SLC6A9,PDE8B,DLL3,ATP1A3,ARPP21,ADGRB2,C11orf87,NELL1,ACSBG1,C1QC,GNG4,UNC5D,ADGRL3,TMEM136,GRIA1,OPCML,TMEM25,REPS2,NXPH1,PLCH2,MASP1,ZNF385B,CADM2,LRP8,KCNA6,PCDH15,DLG2,RALGDS,PRRT4" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500 facebase_RNAseq_e10.5_OlfacPit_2500 Gudmap RNAseq 5.97E-06 2.65E-02 4.63E-05 4.15E-04 86 1453 "DPF1,TTYH1,MAP6,RIMKLA,MAPT,ACHE,MBP,LGR4,CEND1,ADGRV1,EYA1,RTN1,DSCAML1,GRAMD1B,TUBB4A,LRRTM4,BCAR3,TRIM46,AMPH,ANK3,CNIH2,APBB1,APC,DGKZ,SHTN1,CLSTN1,CADPS,TAGLN3,SNAP25,PHYHIPL,SCN3B,MYBPC1,KIF21B,CADM3,STARD10,RAP1GAP2,NASP,INKA2,RCOR2,GNG3,WWC1,WSCD1,GPM6A,GPM6B,CACNB2,B4GALNT4,HAP1,PTBP2,CECR2,BRSK2,GRIK2,SHISA7,USP2,MFSD2A,CELF3,TPD52,PDE1C,PRMT8,ADGRG1,CA14,TMEFF2,CADM1,KIAA1549L,NRXN1,FAM181B,MEAF6,CRMP1,NKAIN4,MICAL2,PLCH2,CTNND2,DPYSL5,TUBB2B,DNAJC6,ITIH2,SHD,KCNK1,NAV2,NKAIN1,SUSD4,DTNA,EFNA3,LMO1,RAVER2,ELAVL4,EPB41" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 6.06E-06 2.69E-02 4.69E-05 4.21E-04 15 105 "ACTN2,ADCY2,SLC1A2,ADGRB2,C1QC,ADGRL3,CAMK2A,GRIA1,REPS2,PDE1A,MASP1,ZNF385B,CADM2,PCDH15,DLG2" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 6.20E-06 2.76E-02 4.79E-05 4.30E-04 41 533 "ADCYAP1R1,DISP3,FHL1,SFPQ,MAGI3,ZCCHC17,USP16,SCG3,SLCO1A2,B3GAT1,ATM,PHYHIPL,ILDR2,NASP,LMO3,ZNF638,PTBP2,MFSD2A,TJP1,PAX6,TPM3,TPM4,PDE3B,PRMT8,JAM2,SEMA5B,ANLN,NMT2,FLRT1,KCNT2,CTNND2,MAPK8,SPIRE1,JAKMIP2,SMG7,RTN4,RFX4,ABI2,PLEKHO1,EPB41,LRRC23" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.36E-06 2.83E-02 4.91E-05 4.40E-04 33 388 "MEG3,ADCY2,NTNG1,CADPS,SLN,MTR,ADGRL3,KLHL4,ANO4,GPM6B,VWC2,DDR2,GRIA1,GRIA4,REPS2,PCDH8,CDH10,NEGR1,FTO,PRRX1,MED1,RNF14,PTCH1,HP1BP3,RGMA,PTPRD,SRGAP3,NTM,RTN4,ATL1,SSPN,EFNA3,VWA5A" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k2 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.89E-06 3.06E-02 5.31E-05 4.76E-04 26 270 "IL17D,NDRG2,ADARB2,SORCS1,SH3GL2,SORBS1,ASPH,DKK3,TNIK,LMO3,SMOC1,ZNF638,PRUNE2,ADAMTS8,PCDH9,KIAA1549L,CNTN1,PRRX1,VCAN,RBPJ,PRKAB2,IGSF1,PSD,RABGAP1L,KCNMA1,PARP11" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.94E-06 3.08E-02 5.34E-05 4.79E-04 18 147 "MEG3,ADCY2,FABP7,LRRC4C,PALLD,NCAM1,NFIA,MYRF,PSD3,GUCY1A2,GUCY1A1,CDH10,PRRX1,TENM4,ATRNL1,VCAN,SV2A,TMEM255A" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_500 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500 PCBC 7.19E-06 3.19E-02 5.52E-05 4.95E-04 39 499 "MAP6,EMID1,WLS,SLC30A10,CCDC80,BCO1,TAGLN3,PHYHIPL,SOX5,ILDR2,COLGALT2,STOX1,SMOC1,GPR162,NHLH1,FAM69C,ZEB1,AZIN2,CAMK2A,CELF3,KCNK10,PAX6,LGI1,PDE1C,FNDC5,HAPLN2,COL9A2,POU3F2,PLCH2,PLPP4,HES5,ZBTB16,DPYSL5,ZNF385B,STMN4,KCNA1,OLFM3,RFX4,RLBP1" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.28E-06 3.24E-02 5.58E-05 5.01E-04 55 809 "SYNDIG1,MRVI1,ADCY2,HOGA1,ASRGL1,CCDC80,DGKD,ST8SIA1,MSR1,DACH2,CADPS,CGREF1,PALLD,DKK3,ADGRB2,NCAM1,CLASP2,NFIA,SYT4,CAMSAP2,ANO4,VWC2,B4GALNT4,NRDC,GRIA1,GRIA4,GRIK2,GUCY1A1,PCDH8,PCDH9,DCLK1,RBFOX2,TMEFF2,NEGR1,CNTN1,PRRX1,FAT3,CNRIP1,SNCAIP,NKAIN4,ATRNL1,VCAN,PKN2,SPIRE1,TUBB2B,SMG7,PTPRO,KCND3,NTM,PID1,GOPC,ZYG11B,CBLN2,EPB41L2,RASGRP2" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.74E-06 3.44E-02 5.92E-05 5.31E-04 32 374 "ACER3,LGR4,MEG3,EYA1,FABP7,SOX6,DOCK10,PKNOX2,SORCS3,TMEM108,PALLD,TNIK,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,GRIA4,TGFBR3,GUCY1A1,PCDH9,PDE1A,HPSE2,SERPINE2,FAT3,TENM4,MICAL2,VCAN,PTCH1,SV2A,TMEM255A" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.84E-06 3.48E-02 5.98E-05 5.37E-04 54 791 "MEG3,NDRG2,ADD3,PNMA8B,LRRTM4,KIAA1109,FGF1,SEMA6C,SFPQ,PKP4,ARHGAP5,SCMH1,ARFGAP1,ASPH,SNAP25,ATP1A2,MYBPC1,ZCCHC24,ILDR2,KIF1B,NASP,NCAM1,NFIA,PCDH11X,BTRC,KLHL4,VSTM2A,TNS1,PCDH9,DCLK1,RBFOX2,UBTF,NMT2,FLRT1,COL9A2,PRRX1,FAT3,TENM4,FEZ1,DZIP3,MAPK8,PUM1,FGFR1OP2,PMEPA1,ZC3H11A,KCND3,NAV2,SNX27,TMEM255A,ABCC9,JMJD1C,CACNG7,VWA5A,EPB41L2" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000_k5 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.19E-06 3.64E-02 6.24E-05 5.60E-04 28 306 "MBP,SLITRK1,SORCS1,SCN4B,BCAR3,SOX6,SH3GL2,PDE8B,MYH7,RAP1GAP2,GFRA1,UNC5D,WSCD1,GRIK2,MFSD2A,PADI2,MAGI1,PRMT8,KIAA1549L,SEMA5B,PHACTR3,CTNND2,TOX,DPYSL5,PTPRZ1,SUSD4,L1CAM,RET" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE76381_iPSMoleculeCountsPMLog2 8.51E-06 3.78E-02 6.43E-05 5.77E-04 9 39 "RTN1,ANK3,NSG2,SNAP25,SCN3B,NCAM1,INA,PRKACB,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.51E-06 3.78E-02 6.43E-05 5.77E-04 9 39 "SNAP25,SCN3B,SEPT3,ARHGEF7,GPM6A,CELF3,CELF5,STMN4,ELAVL3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.51E-06 3.78E-02 6.43E-05 5.77E-04 9 39 "RTN1,ANK3,NSG2,SNAP25,SCN3B,NCAM1,INA,PRKACB,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.51E-06 3.78E-02 6.43E-05 5.77E-04 9 39 "MEG3,RTN1,SCN3A,NSG2,SCN3B,INA,CNTN1,PLPPR5,DNAJC6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 8.51E-06 3.78E-02 6.43E-05 5.77E-04 9 39 "MEG3,RTN1,SCN3A,NSG2,SCN3B,INA,CNTN1,PLPPR5,DNAJC6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 8.70E-06 3.87E-02 6.57E-05 5.89E-04 7 22 "FABP7,CADPS,SCG3,INA,PTPRZ1,DLG2,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 8.75E-06 3.89E-02 6.59E-05 5.91E-04 10 49 "SNAP25,SCN3B,DNER,C11orf87,BRSK2,CNTN1,NRSN1,MAPK10,RET,ELAVL4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k4 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.79E-06 3.91E-02 6.61E-05 5.93E-04 19 164 "RIMKLA,EYA1,FGF1,AMPH,SGIP1,SFMBT2,ATP1A2,MYBPC1,FXYD6,NELL1,CECR2,FAT3,NXPH1,SNCAIP,VCAN,PTHLH,ITIH2,DTNA,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_200 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.87E-06 3.94E-02 6.66E-05 5.97E-04 12 71 "EPS8,ADORA1,SEMA6C,SH3GL2,GPM6B,JAM2,SERPINE2,TOX,JAKMIP2,ELMO1,PLPPR4,DTNA" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.26E-06 4.12E-02 6.94E-05 6.23E-04 56 836 "ABAT,PRR5L,MAPT,CDHR1,EMID1,SYT9,LGR4,EYA1,MRVI1,ADORA1,FCGR1A,AMPH,SGIP1,PPM1E,DOCK10,ST8SIA1,MSR1,DACH2,DKK3,ILDR2,KIF1B,NCAM1,C11orf87,NELL1,C1QC,CAMTA1,ANO4,ACSL6,VWC2,DDR2,GRIA4,GRM3,TF,P2RX7,ZFP91,TPD52,MS4A7,NEGR1,NMT2,CNTN1,SNCAIP,VCAN,SIRPA,ELMO1,MAGI2,KCNA1,PTPRO,KCND3,CCDC3,KCNK2,DNM2,C12orf4,RASGRF1,FAM13C,DTNA,TTLL7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.32E-06 4.14E-02 6.97E-05 6.26E-04 11 60 "EYA1,SORCS1,SCN3A,SGIP1,CADPS,NAP1L2,ACSL6,CDH10,DCLK1,JAKMIP2,ST8SIA3" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K1 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 9.87E-06 4.39E-02 7.37E-05 6.62E-04 25 259 "FHL1,PHYHIPL,ILDR2,LMO3,ZNF638,GNG3,TCF7L2,PTBP2,RFFL,CDK11B,PAX6,TPM3,PRMT8,KIAA1549L,NRXN2,ANLN,NMT2,CTNND1,CTNND2,MASP1,JAKMIP2,PTPRZ1,CAB39L,RFX4,EPB41" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_500 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.03E-05 4.55E-02 7.64E-05 6.86E-04 35 433 "LGR4,MEG3,F3,FABP7,SOX6,RASA3,CACHD1,ST8SIA1,PKNOX2,MTR,TMEM108,PALLD,SOX5,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,GUCY1A1,DAAM2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,PFKFB3,TMEFF2,PRRX1,TENM4,MICAL2,ATRNL1,VCAN,TMEM255A" Coexpression Atlas gudmap_developingGonad_P2_testes_1000 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.04E-05 4.60E-02 7.71E-05 6.92E-04 55 819 "TTYH1,ACLY,MEG3,ARID1A,ADCYAP1R1,WAC,ADORA1,AGT,SFPQ,SH3GL2,DGKD,BCAN,SLC1A6,MT3,ATP1A2,FYN,SON,ZCCHC24,ACSBG1,NFIA,MMD2,BTRC,GPM6B,DDR1,CAMK2G,VXN,MAEL,CDC42,TNS1,RBFOX2,ADGRG1,JAM2,SEMA5B,UBTF,FADS2,FLRT1,CABP1,CP,PNKD,SF1,RNF14,PRKACB,ARHGEF4,CTNND1,PUM1,ZBTB16,TOX,TUBB2B,PTPRE,PLPPR4,PYGM,KIF2A,DTNA,RTN4,EPB41L2" Coexpression Atlas ratio_SC_vs_DE_1000_K5 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 1.05E-05 4.66E-02 7.77E-05 6.98E-04 19 166 "SCN4B,TMEM151A,ATP1A2,ATP1A3,CPLX2,DNER,ALDH1L1,SLCO1C1,ABCC8,TLL2,TNFRSF1B,ST8SIA5,CABP1,SLC45A1,PSD,PTPRO,PYGM,SUSD4,ARHGEF10L" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.05E-05 4.66E-02 7.77E-05 6.98E-04 19 166 "RTN1,SORCS1,SGIP1,APC,SNAP25,SCN3B,C11orf87,GFRA1,NFIA,CDH10,RBFOX2,PRRX1,TENM4,VCAN,MAPK10,PTPRO,KCNMA1,CALN1,NUP214" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_500_k1 DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.10E-05 4.89E-02 8.15E-05 7.31E-04 11 61 "TTYH1,CSMD3,SORCS1,SGIP1,DNER,C11orf87,MMD2,MAEL,JAM2,RASGRF1,CBLN2" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.14E-05 5.06E-02 8.42E-05 7.56E-04 34 417 "MEG3,FABP7,PNMA8B,DRAXIN,LINC00461,SFPQ,PKP4,NSG2,SCMH1,SPHKAP,TAGLN3,SNAP25,MYBPC1,KIF1B,DNER,NAP1L2,NASP,RGL1,NEUROD1,PCDH11X,KLHL4,PCDH8,CDH10,DCLK1,RBFOX2,PRRX1,NSD2,CRMP1,MAPK8,PUM1,FGFR1OP2,ZC3H11A,SNX27,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.16E-05 5.17E-02 8.59E-05 7.71E-04 23 229 "PRR5L,EYA1,SGIP1,ZNF365,DNER,UNC5D,ADGRL3,GPR17,PTBP2,DDR2,GRIA2,PCDH8,DCLK1,NLGN3,CELF5,PRRX1,PPP3CB,FMN2,TOX,LRRTM3,MAGI2,TMEM255A,EFNA3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.25E-05 5.54E-02 9.19E-05 8.25E-04 53 784 "LGR4,MEG3,ATAT1,ADCY2,FABP7,KIAA1109,RASA3,SESN3,CCDC80,GPAM,CACHD1,LRRC4C,ST8SIA1,SCMH1,MTR,PALLD,ZCCHC24,NPAS3,NCAM1,SMOC1,NELL1,NFIA,PCDH11X,MYRF,ADGRL3,GPM6B,CACNB2,TCF12,PSD3,GUCY1A2,GUCY1A1,ATG4C,DAAM2,REPS2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,CHRM4,VAV2,PRRX1,FAT3,TENM4,ATRNL1,VCAN,PRKACB,MAGI2,PTPRD,SV2A,SRGAP3,NAV2,TMEM255A" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.26E-05 5.60E-02 9.27E-05 8.32E-04 37 474 "EPS8,ACLY,EYA1,F3,ADORA1,BCAR3,FHL1,SOX6,SEMA6C,SH3GL2,DOCK10,GAS7,KIAA1614,CADPS,CSPG5,TNIK,SOX10,FXYD6,NELL1,ADHFE1,SEMA4A,GPM6B,DDR1,NRDC,MFSD2A,PADI2,ADGRG1,SERPINE2,CP,DOCK7,ARHGEF4,MASP1,JAKMIP2,PLPPR4,KCNH1,DTNA,SIDT2" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.26E-05 5.61E-02 9.27E-05 8.32E-04 33 401 "PRR5L,EMID1,SLITRK1,SORCS1,SCN3A,SCN4B,SEMA6A,AQP4,PDE8B,RAP1GAP2,GFRA1,KIRREL3,UNC5D,WWC1,CNDP1,WSCD1,B4GALNT4,GRIK2,MFSD2A,PADI2,PRMT8,CA14,PFKFB3,SEMA5B,SF1,PHACTR3,CTNND2,LRP8,KCNK1,NKAIN1,L1CAM,RET,C2orf80" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_1000 DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.29E-05 5.74E-02 9.48E-05 8.51E-04 53 785 "TTYH1,SERPINA3,MBP,PAQR6,CSMD3,NDRG2,FABP7,SORCS1,ADORA1,FHL1,SGIP1,PI16,SH3GL2,GAS7,AQP4,MSR1,SLC14A1,CGREF1,PDE8B,GPR153,SORCS3,ATP1A2,DKK3,SCN3B,ILDR2,CPLX2,DNER,C11orf87,ALDH1L1,ADHFE1,NFIA,PCDH11X,SEMA4A,MMD2,VXN,PAH,MAEL,TNFRSF1B,JAM2,CNTN1,MICAL1,MFSD4A,CP,NKAIN4,ZBTB16,ELMO1,RABGAP1L,RASGRF1,ABCC9,SH3GLB1,CBLN2,TMEM100,RCAN2" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.61E-05 7.16E-02 1.18E-04 1.06E-03 34 424 "LGR4,FABP7,DOCK10,SESN3,CCDC80,CACHD1,LRRC4C,MTR,TMEM108,PALLD,ZCCHC24,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,PSD3,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,PDE1A,TMEFF2,PRRX1,FAT3,TENM4,ATRNL1,VCAN,SYTL2,SV2A,TMEM255A" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.65E-05 7.33E-02 1.21E-04 1.08E-03 62 977 "EMID1,ACTN2,MEG3,NDRG2,ADCY2,CHST15,TESK2,LRRTM4,CDC42BPA,DOCK10,NTNG1,CCDC80,ZCCHC17,NLGN1,SLC1A2,YPEL4,ASTN1,TMEM151A,CCDC181,NRG3,JPH4,STARD10,ADGRB2,NPAS3,NDUFA5,NFIA,PCDH11X,C1QC,SEMA4A,ADGRL3,DDR1,DIRAS1,CAMK2G,PSD3,MFSD2A,TMEM9,REPS2,PCDH9,PDE1A,ACOT7,NLGN3,KIAA1549L,NRXN1,FLRT1,CCDC136,CELF5,NECAB2,NXPH1,NKAIN4,FEZ1,VCAN,FMN2,TOX,PMEPA1,CADM2,PTPRZ1,CCDC3,PCDH15,DLG2,RGS10,EFNA3,VWA5A" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.66E-05 7.36E-02 1.21E-04 1.09E-03 7 24 "MRVI1,DACH2,CADPS,VWC2,NEGR1,CNTN1,EPB41L2" Coexpression Atlas PCBC_ctl_geo-heart_500 geo_heart_top-relative-expression-ranked_500 PCBC 1.68E-05 7.47E-02 1.23E-04 1.10E-03 38 499 "SERPINA3,DUSP27,RCSD1,SYNDIG1,ACTN2,KCNIP2,HHATL,AGT,FGR,ANK1,PI16,SORBS1,MT3,SPHKAP,SLN,KBTBD12,ATP1A2,ATP1A3,MYH7,IDI2-AS1,NCAM1,ALDH1L1,C1QC,VWC2,NPPA,CACNB2,GPR17,CAMK2A,USP2,CHI3L2,DUSP26,PHKG1,HPR,DKFZp779M0652,KCND3,PYGM,EEF1A2,RCAN2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.73E-05 7.69E-02 1.26E-04 1.13E-03 29 336 "NDRG2,ADCY2,ADCYAP1R1,FABP7,NTNG1,GPAM,PKNOX2,ARFGAP1,SORCS3,PALLD,ZCCHC24,NCAM1,PSD3,GRIA4,TGFBR3,GUCY1A2,GUCY1A1,PCDH9,HPSE2,TMEFF2,FAT3,SNCAIP,TENM4,MICAL2,VCAN,SYTL2,PTCH1,KCND3,EPB41L2" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500_K0 facebase_RNAseq_e8.5_FloorPlate_2500_K0 Gudmap RNAseq 1.77E-05 7.87E-02 1.29E-04 1.16E-03 11 64 "TTYH1,MAP6,ADGRV1,TUBB4A,WSCD1,CAMK2A,CECR2,GRIK2,CELF3,ZBTB16,DPYSL5" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.80E-05 7.98E-02 1.30E-04 1.17E-03 33 408 "EYA1,RTN1,SORCS1,SCN3A,SGIP1,ANK3,APC,DACH2,SNAP25,NAP1L2,NPAS3,SMOC1,GFRA1,NFIA,PCDH11X,VSTM2A,GRIA2,GRM3,INA,GUCY1A1,CDH10,RBFOX2,PRRX1,FAT3,CRMP1,VCAN,TOX,JAKMIP2,KCND3,ARNT2,KCNMA1,HS3ST4,ABCC9" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.89E-05 8.42E-02 1.37E-04 1.23E-03 23 236 "EMID1,CEND1,ERMN,TUBB4A,CCDC80,PKNOX2,ATM,PALLD,JPH4,WWC1,WSCD1,CECR2,INA,PDE1A,NLGN3,FLRT1,NKAIN4,ZBTB16,CA10,SHD,CDH20,ST8SIA3,PIANP" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.01E-05 8.93E-02 1.45E-04 1.30E-03 86 1501 "TTYH1,EMID1,TMEM74,CNTNAP3,PAQR6,ATAT1,WLS,CLIP1,GRAMD1B,PLA2G6,BCAR3,SEMA6C,ASRGL1,ANK2,APBA2,APBB1,SESN3,CCDC80,DGKD,NLGN1,ST3GAL3,PAAF1,CLSTN1,NBPF1,BCO1,PKNOX2,SCMH1,GPR153,ASTN1,ATP1A2,PALLD,WDTC1,SOX1,CADM3,ILDR2,ZSWIM8,NEK6,FXYD6,COLGALT2,STOX1,SMOC1,GPR162,DCAF5,RGL1,VAMP1,DDHD2,ADGRL3,ATF7,PCDHGA3,NUMA1,CROCCP2,PTPN5,TGFBR3,KCNK10,PAX6,CDH8,LGI1,FNDC5,ADGRG1,CADM1,CPT1C,CCDC136,C11orf49,SLC25A27,MICAL1,COL9A2,SPATA6,POU3F2,NKAIN4,ARHGEF4,CTNND2,HES5,ZBTB16,DPYSL5,ZNF385B,HP1BP3,RGMA,OLFM3,PTPRD,CAB39L,RAB5B,PARP11,RALGDS,SIDT2,PIANP,BAALC" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.06E-05 9.17E-02 1.49E-04 1.34E-03 11 65 "EYA1,SORCS1,SCN3A,SGIP1,DACH2,CADPS,ASTN1,NAP1L2,DCLK1,FMN2,JAKMIP2" Coexpression Atlas gudmap_developingGonad_e12.5_testes_1000 DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.07E-05 9.19E-02 1.49E-04 1.34E-03 54 819 "ACLY,MEG3,ARID1A,KIAA1109,SFPQ,SESN3,DGKZ,DGKD,SCMH1,ATM,FYN,SON,SOX5,ZCCHC24,NEK6,GART,ADGRB2,NASP,SPART,NCAM1,OS9,MYRF,MMD2,BTRC,KLHL4,GPM6B,DDR1,CAMK2G,LEFTY2,MAEL,CDC42,TNS1,RBFOX2,ZMYND8,ADGRG1,SEMA5B,COL9A2,RNF14,PRKACB,CTNND1,MAPK8,PUM1,FGFR1OP2,TUBB2B,COPS7A,PTPRD,PTPRE,KCNH1,KIF2A,TMEM255A,DTNA,RTN4,VANGL2,EPB41L2" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.07E-05 9.19E-02 1.49E-04 1.34E-03 54 819 "PRR5L,LGR4,ADGRV1,MRVI1,ADCY2,GALNT13,SORCS1,SCN3A,LRRTM4,SEMA6A,SFPQ,ANK3,DOCK10,NTNG1,ST8SIA1,SLCO1A2,ASPH,KIF1B,DNER,RGL1,KIRREL3,RHBDL3,PCDH11X,ADGRL3,ANO4,ZEB1,DDR2,GRIA1,GRIA4,GRM3,ZFP91,REPS2,PCDH8,CDH10,ARHGAP19,PDE4B,CADM1,NEGR1,ANLN,ITGAV,PTPRD,NTM,AK5,CCDC3,KIF2A,CALN1,GOPC,FAM13C,ABCC9,CRTAC1,SEC61A2,EFNA3,ABI2,VWA5A" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_1000 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.07E-05 9.21E-02 1.49E-04 1.34E-03 56 860 "SDE2,ABAT,LGR4,MEG3,F3,CLIP1,ADCY2,SLITRK1,FABP7,TUBB4A,SOX6,RASA3,SESN3,CCDC80,CACHD1,LRRC4C,ST8SIA1,PKNOX2,MTR,TMEM108,PALLD,NEK6,NCAM1,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,CACNB2,PSD3,GUCY1A2,GUCY1A1,DAAM2,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,PFKFB3,CHRM4,TMEFF2,VAV2,PRRX1,TENM4,ATRNL1,VCAN,SYTL2,TUBB2B,MAGI2,KCNH1,SV2A,SRGAP3,NAV2,TMEM255A,EPB41L1" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K4 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 2.14E-05 9.52E-02 1.54E-04 1.38E-03 25 271 "SYNDIG1,NDRG2,DSCAML1,HHATL,PNMA8B,GRAMD1B,SOX6,GPAM,KIAA1614,PKNOX2,SPHKAP,CADM3,SLCO1C1,POPDC3,HAPLN2,JAM2,DUSP26,ETNPPL,SHD,CCDC3,SLC25A18,CRTAC1,ARHGEF10L,SYT15,TMEM100" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.15E-05 9.57E-02 1.54E-04 1.38E-03 26 288 "ADCY2,LRRTM4,ANK2,SESN3,NTNG1,ST8SIA1,ZCCHC24,NFIA,ADGRL3,KLHL4,ANO4,DDR2,GRIA1,GRIA4,GRM3,REPS2,CDH10,PDE1A,RNF14,CEP170,PTPRD,SRGAP3,NTM,FAM13C,SSPN,VWA5A" Coexpression Atlas gudmap_developingGonad_e11.5_testes_1000 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.33E-05 1.03E-01 1.66E-04 1.49E-03 55 843 "MAPT,ACLY,MEG3,ATAT1,ARID1A,FABP7,LINC00461,FOXM1,SFPQ,ITSN1,DGKZ,ASCL1,TAGLN3,DLL3,SNAP25,SON,SOX5,ZCCHC24,NEK6,GART,NASP,SPART,NCAM1,NEUROD1,OS9,GNG3,MYRF,BTRC,KLHL4,GPM6B,DDR1,CAMK2G,DDR2,INA,TMEM9,CDC42,TNS1,RBFOX2,ZMYND8,FADS2,SF1,CRMP1,RNF14,PRKACB,PUM1,KIAA0408,TUBB2B,BLOC1S6,PEX5,RTN4,RFX4,VANGL2,ELAVL4,PLEKHO1,EPB41L2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 2.38E-05 1.06E-01 1.70E-04 1.52E-03 37 488 "RPL38,ADGRV1,NDRG2,RTN1,ADCY2,TUBB4A,SEMA6A,DOCK10,NTNG1,CCDC80,ASTN1,DKK3,JPH4,ADGRB2,NFIA,PCDH11X,C1QC,ADGRL3,WSCD1,PAX6,REPS2,PCDH9,HPSE2,KIAA1549L,SEMA5B,POU3F4,FEZ1,FMN2,CTNND2,TOX,DPYSL5,PMEPA1,CADM2,NTM,CCDC3,PCDH15,RGS10" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.53E-05 1.12E-01 1.80E-04 1.62E-03 33 415 "PRR5L,MAPT,CDHR1,SYT9,EYA1,MRVI1,ADORA1,FCGR1A,SGIP1,ST8SIA1,MSR1,DACH2,DKK3,ILDR2,NCAM1,NELL1,ANO4,ACSL6,VWC2,GRM3,TF,ZFP91,MS4A7,NEGR1,CNTN1,SNCAIP,KCNA1,PTPRO,KCND3,CCDC3,DNM2,FAM13C,TTLL7" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500_k3 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.71E-05 1.20E-01 1.92E-04 1.73E-03 20 193 "SLITRK1,SORCS1,SCN4B,SEMA6A,PDE8B,RAP1GAP2,GFRA1,KIRREL3,UNC5D,WSCD1,GRIK2,MFSD2A,PADI2,PRMT8,PFKFB3,SEMA5B,PHACTR3,CTNND2,L1CAM,RET" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.92E-05 1.30E-01 2.07E-04 1.86E-03 8 35 "SCN3A,ST8SIA1,DACH2,CADPS,ASTN1,NAP1L2,NPAS3,CDH10" Coexpression Atlas PCBC_ratio_ECTO cord blood_vs_ECTO blastocyst_cfr-2X-p05 ECTO cord blood_vs_ECTO blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.11E-05 1.38E-01 2.20E-04 1.98E-03 15 120 "DRAXIN,SOX1,DNER,RGL1,RND1,ROBO3,KLHL4,GPM6B,GRIA1,KCNK10,LGI1,FAM13C,RFX4,CACNG7,FGFBP3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.12E-05 1.38E-01 2.21E-04 1.98E-03 32 401 "PRR5L,RIMKLA,CDHR1,EYA1,FGF1,AMPH,SGIP1,ANK3,APC,SFMBT2,DACH2,ATP1A2,MYBPC1,FXYD6,GFRA1,NELL1,CAMTA1,CAMSAP2,CECR2,ZFP91,NEGR1,FAT3,NXPH1,SNCAIP,VCAN,PTHLH,ITIH2,LRP8,DTNA,CRTAC1,NUP214,ELAVL4" Coexpression Atlas geo_heart_1000_K4 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 3.14E-05 1.40E-01 2.22E-04 1.99E-03 17 149 "HHATL,LCNL1,HOGA1,FGF1,PI16,SLN,DKK3,MYBPC1,IDI2-AS1,GFAP,ABCC8,NPPA,VXN,PACSIN1,KIAA1755,SHD,KCNJ4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.19E-05 1.42E-01 2.25E-04 2.02E-03 27 312 "KIAA1109,ANK3,APC,KIF1B,C11orf87,CLASP2,SMOC1,GFRA1,RGL1,NFIA,PCDH11X,CAMSAP2,GRIA2,GUCY1A1,RBFOX2,PRRX1,FAT3,NKAIN4,VCAN,MAPK8,TOX,ELMO1,AK5,ARNT2,ZYG11B,NUP214,EPB41" Coexpression Atlas GSM605808_500 "gamma delta T cells, Tgd.vg5-.act.IEL, CD8a+ CD8b- TCRd+ Vg5- CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 3.27E-05 1.45E-01 2.30E-04 2.07E-03 32 402 "PRR5L,EMID1,WLS,GRAMD1B,FGR,SESN3,STK32C,NSG2,FYN,TNIK,ACSBG1,B4GALNT4,AKNA,P2RX7,TNFRSF1B,PADI2,PDE3B,ACOT7,FADS2,PPP2R5C,OSBPL3,PRKACB,TOX,SYTL2,DNAJC6,ITGAV,PMEPA1,SRGAP3,RABGAP1L,KCNK1,SUSD4,EPB41" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000 DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.45E-05 1.53E-01 2.42E-04 2.18E-03 53 814 "TTYH1,MAPT,ACLY,MEG3,ARID1A,DSCAML1,ADCYAP1R1,ADORA1,AGT,SH3GL2,DGKD,SLC1A6,MT3,DDX25,FYN,SON,ZCCHC24,ACSBG1,NFIA,OS9,MMD2,BTRC,GPM6B,DDR1,CAMK2G,VXN,GUCY1A1,MAEL,PC,CDC42,TNS1,RBFOX2,ZMYND8,ADGRG1,JAM2,SEMA5B,UBTF,FADS2,FAM181B,RNF14,SNCAIP,PRKACB,ARHGEF4,CTNND1,PUM1,TUBB2B,PTPRE,PLPPR4,KCNH1,KIF2A,DTNA,RTN4,EPB41L2" Coexpression Atlas PCBC_ratio_MESO-30 fibroblast_vs_MESO-30 blastocyst_cfr-2X-p05 MESO-30 fibroblast_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.65E-05 1.62E-01 2.55E-04 2.29E-03 38 517 "RCSD1,ACTN2,IL17D,WLS,SLC44A5,FHL1,USP28,SESN3,CCDC80,CSPG5,SLN,PALLD,DKK3,ZCCHC24,MYH7,INKA2,C1QC,POPDC3,KLHL4,ANO4,NPPA,DDR2,PSD3,LEFTY2,GUCY1A1,DAAM2,TNS1,DUSP26,SERPINE2,PRRX1,ATRNL1,PLPP4,BRINP3,PTCH1,PTHLH,NTM,CCDC3,SSPN" Coexpression Atlas PCBC_ratio_MESO-30_from-OSKM - NLT_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-reprogram_OSKM - NLT_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.65E-05 1.62E-01 2.55E-04 2.29E-03 38 517 "RCSD1,ACTN2,IL17D,WLS,SLC44A5,FHL1,USP28,SESN3,CCDC80,CSPG5,SLN,PALLD,DKK3,ZCCHC24,MYH7,INKA2,C1QC,POPDC3,KLHL4,ANO4,NPPA,DDR2,PSD3,LEFTY2,GUCY1A1,DAAM2,TNS1,DUSP26,SERPINE2,PRRX1,ATRNL1,PLPP4,BRINP3,PTCH1,PTHLH,NTM,CCDC3,SSPN" Coexpression Atlas PCBC_ratio_MESO-30_from-plasmid_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-method_plasmid_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.65E-05 1.62E-01 2.55E-04 2.29E-03 38 517 "RCSD1,ACTN2,IL17D,WLS,SLC44A5,FHL1,USP28,SESN3,CCDC80,CSPG5,SLN,PALLD,DKK3,ZCCHC24,MYH7,INKA2,C1QC,POPDC3,KLHL4,ANO4,NPPA,DDR2,PSD3,LEFTY2,GUCY1A1,DAAM2,TNS1,DUSP26,SERPINE2,PRRX1,ATRNL1,PLPP4,BRINP3,PTCH1,PTHLH,NTM,CCDC3,SSPN" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.65E-05 1.62E-01 2.55E-04 2.29E-03 31 386 "LGR4,MEG3,FABP7,SOX6,RASA3,CCDC80,ST8SIA1,MTR,TMEM108,PALLD,SMOC1,NFIA,PCDH11X,MYRF,ADGRL3,CACNB2,GUCY1A2,GUCY1A1,DAAM2,PCDH9,CDH10,DCLK1,MAGI1,PDE1A,FNDC5,PRRX1,FAT3,ATRNL1,MAGI2,SRGAP3,TMEM255A" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 3.85E-05 1.71E-01 2.69E-04 2.41E-03 19 182 "EMID1,ERMN,TUBB4A,NTNG1,CCDC80,TMEM108,JPH4,SALL3,AJAP1,ROBO3,CECR2,INA,PDE1A,FLRT1,ZBTB16,CA10,CDH20,ST8SIA3,SEZ6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.87E-05 1.72E-01 2.69E-04 2.42E-03 7 27 "TUBB4A,TAGLN3,GNG3,CELF3,ACOT7,GDAP1L1,CRMP1" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000 DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.05E-05 1.80E-01 2.82E-04 2.53E-03 53 819 "TTYH1,MAPT,ACLY,ACTN2,MEG3,ARID1A,DSCAML1,AGT,SFPQ,DGKD,SLC1A6,DDX25,MTR,FYN,SON,ZCCHC24,ENKUR,SPART,NCAM1,ACSBG1,NFIA,OS9,MMD2,BTRC,GPM6B,DDR1,CAMK2G,LEFTY2,MAEL,PC,CDC42,TNS1,RBFOX2,ADGRG1,SEMA5B,PIK3CD,UBTF,FADS2,RNF14,SNCAIP,PRKACB,CTNND1,PUM1,TUBB2B,PMEPA1,PTPRE,PLPPR4,KCNH1,KIF2A,DTNA,RTN4,VANGL2,EPB41L2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.06E-05 1.80E-01 2.82E-04 2.53E-03 22 231 "LGR4,RASA3,CCDC80,CACHD1,ST8SIA1,MTR,MYBPC1,SOX5,SMOC1,NFIA,PCDH11X,ADGRL3,CACNB2,DAAM2,DCLK1,MAGI1,PDE1A,FNDC5,NOS1AP,MAGI2,SRGAP3,NAV2" Coexpression Atlas GSM538258_500 "Myeloid Cells, DC.8+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-2" "Immgen.org, GSE15907" 4.15E-05 1.85E-01 2.88E-04 2.59E-03 32 407 "EPS8,PRR5L,ACER3,RTN1,ADORA3,FGR,SHTN1,ARHGAP5,CCDC88A,NEK6,RGL1,SEPT3,ADGRL3,CACNA1E,CLEC9A,CYB561A3,CD81,HPS5,PFKFB3,ARHGAP22,CADM1,ZFYVE9,PRKAB2,DOCK7,SDC3,RAB39A,CTNND1,PTAFR,SRGAP3,PID1,PIANP,PLEKHO1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.21E-05 1.87E-01 2.92E-04 2.62E-03 9 47 "RTN1,SNAP25,SCN3B,C11orf87,CDH10,MAPK10,PTPRO,KCNMA1,CALN1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_100 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.23E-05 1.88E-01 2.92E-04 2.62E-03 11 70 "EYA1,RTN1,FABP7,CADPS,TAGLN3,SCN3B,GNG3,TMEFF2,FAT3,MAPK10,STMN4" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.33E-05 1.92E-01 2.99E-04 2.68E-03 18 168 "EPS8,ADORA1,BCAR3,SEMA6C,SH3GL2,CADPS,TNIK,GPM6B,PADI2,JAM2,SERPINE2,MASP1,TOX,JAKMIP2,ELMO1,PLPPR4,GNE,DTNA" Coexpression Atlas gudmap_developingGonad_P2_testes_500 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.36E-05 1.94E-01 3.00E-04 2.69E-03 32 408 "TTYH1,ACLY,MEG3,ARID1A,ADCYAP1R1,ADORA1,SH3GL2,SLC1A6,MT3,FYN,ZCCHC24,ACSBG1,MMD2,BTRC,GPM6B,DDR1,VXN,MAEL,ADGRG1,JAM2,SEMA5B,FADS2,RNF14,ARHGEF4,PUM1,TOX,TUBB2B,PTPRE,PLPPR4,DTNA,RTN4,EPB41L2" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 Gudmap RNAseq 4.51E-05 2.00E-01 3.10E-04 2.78E-03 54 843 "ABAT,MAP6,MAPT,ACHE,EMID1,RCSD1,PAQR6,MRVI1,WLS,NDRG2,ADORA1,CHST15,FGF1,BCAR3,FHL1,DOCK10,CCDC80,BCAS1,PDE8B,GPR153,ZCCHC24,RGL1,TMEM136,NRGN,TF,TGFBR3,GUCY1A2,P2RX7,GUCY1A1,DAAM2,TNFRSF1B,TNS1,PDE1A,TMEFF2,SERPINE2,PIK3CD,CP,FEZ2,MICAL2,PRKAB2,SDC3,ACY3,RGMA,KCND3,SV2A,PYGM,PLEKHB2,FAM13C,ABCC9,ARHGEF10L,SSPN,ROM1,RCAN2,RASGRP2" Coexpression Atlas gudmap_developingGonad_P2_testes_1000_k4 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.68E-05 2.08E-01 3.21E-04 2.89E-03 27 319 "TTYH1,MEG3,ADCYAP1R1,ADORA1,SH3GL2,BCAN,SLC1A6,MT3,ATP1A2,FYN,ACSBG1,MMD2,GPM6B,VXN,ADGRG1,JAM2,SEMA5B,UBTF,FLRT1,CABP1,PNKD,ARHGEF4,TOX,PTPRE,PLPPR4,PYGM,DTNA" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 4.83E-05 2.15E-01 3.32E-04 2.98E-03 26 302 "EMID1,CEND1,ERMN,TUBB4A,FOXRED2,NTNG1,CCDC80,CACHD1,TMEM108,PALLD,JPH4,SALL3,AJAP1,ROBO3,CECR2,INA,PDE1A,FLRT1,FTO,NKAIN4,ZBTB16,CA10,CDH20,ST8SIA3,PIANP,SEZ6" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K5 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 4.84E-05 2.15E-01 3.32E-04 2.98E-03 20 201 "EMID1,CEND1,ERMN,NTNG1,CCDC80,PALLD,JPH4,TTLL9,INA,PDE1A,NLGN3,FLRT1,NKAIN4,ZBTB16,CA10,SHD,CDH20,ST8SIA3,PIANP,LPAR6" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.01E-05 2.23E-01 3.42E-04 3.07E-03 23 251 "EPS8,SEMA6C,DOCK10,GAS7,SHTN1,CADPS,ATP1A2,TNIK,NELL1,ADHFE1,GPM6B,TPD52,ADGRG1,SERPINE2,FADS2,TUBB2B,LRRTM3,PTCH1,PTPRE,KCNH1,KCNK2,DTNA,SIDT2" Coexpression Atlas GSM605839_500 "Myeloid Cells, DC.8-4-11b-.Sp, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Spleen, avg-1" "Immgen.org, GSE15907" 5.25E-05 2.33E-01 3.58E-04 3.22E-03 32 412 "EPS8,PRR5L,ACER3,RTN1,SCN3A,FGR,ST8SIA1,STK32C,SHTN1,CCDC88A,SLC14A1,CADM3,NEK6,RGL1,ADGRL3,GPM6B,CACNA1E,DDR1,CLEC9A,CYB561A3,TNS1,PFKFB3,DOCK7,CTNND2,SIRPA,PTAFR,SRGAP3,DLG2,PID1,DSCAM,L1CAM,PLEKHO1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.51E-05 2.45E-01 3.75E-04 3.37E-03 8 38 "RTN1,CADPS,SNAP25,SCN3B,DNER,CDH10,MAPK10,ELAVL4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.53E-05 2.46E-01 3.76E-04 3.38E-03 11 72 "B3GAT1,SNAP25,SCN3B,SEPT3,ARHGEF7,GPM6A,CELF3,SCRG1,CELF5,STMN4,ELAVL3" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_200 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.54E-05 2.46E-01 3.76E-04 3.38E-03 13 98 "EYA1,AMPH,NCAM1,GFRA1,NELL1,CECR2,CADM1,NEGR1,FAT3,SNCAIP,VCAN,ELAVL4,TMEM100" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 5.97E-05 2.65E-01 4.05E-04 3.63E-03 20 204 "ADCYAP1R1,DISP3,FHL1,SCG3,SLCO1A2,B3GAT1,ATM,PHYHIPL,ILDR2,NASP,LMO3,MFSD2A,PRMT8,JAM2,SEMA5B,KCNT2,CTNND2,JAKMIP2,RFX4,LRRC23" Coexpression Atlas GSM605827_500 "Myeloid Cells, DC.8+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 6.19E-05 2.75E-01 4.19E-04 3.76E-03 31 397 "EPS8,PRR5L,ACER3,RTN1,TMEM156,ADORA3,SHTN1,ARHGAP5,CCDC88A,DKK3,NEK6,SEPT3,ADGRL3,CACNA1E,CLEC9A,CYB561A3,CD81,HPS5,TPD52,PFKFB3,CADM1,ZFYVE9,PRKAB2,DOCK7,SDC3,RAB39A,CTNND1,PTAFR,SRGAP3,PID1,PLEKHO1" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.32E-05 2.81E-01 4.27E-04 3.83E-03 30 379 "SERPINA3,MBP,MRVI1,NDRG2,FGF1,FHL1,ANK1,PI16,SH3GL2,SORBS1,SLC14A1,ATP1A2,DKK3,DNER,POPDC3,SEMA4A,TF,TNS1,MFSD4A,CP,OSBPL3,PLCH2,SYTL2,PTHLH,KCNA1,KCND3,FAM13C,DTNA,ABCC9,TTLL7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k4 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.32E-05 2.81E-01 4.27E-04 3.83E-03 30 379 "ACTN2,MEG3,ELMOD1,SLC30A10,FOXG1,SOX6,YPEL4,SLN,MTR,MYBPC1,MYH7,ARPP21,ALDH1L1,ADHFE1,MMD2,VWC2,GRIA1,GRIA4,VWCE,TF,PAH,MAEL,TPM3,IFFO1,IGSF1,MASP1,SPIRE1,ITIH2,TMCC2,EPB41" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.38E-05 2.83E-01 4.30E-04 3.86E-03 7 29 "TUBB4A,GNG3,CELF3,SCRG1,CHGA,TMEFF2,ATL1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.43E-05 2.86E-01 4.33E-04 3.89E-03 12 86 "EYA1,SORCS1,LRRTM4,SGIP1,NTNG1,DACH2,DNER,NAP1L2,NPAS3,ADGRL3,DCLK1,PRRX1" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k5_1000 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.64E-05 2.95E-01 4.46E-04 4.01E-03 17 158 "MEG3,DGKD,FYN,MMD2,GPM6B,DDR1,LEFTY2,MAEL,TNS1,ADGRG1,SEMA5B,COL9A2,PUM1,PTPRE,KCNH1,DTNA,EPB41L2" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k5 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.88E-05 3.06E-01 4.62E-04 4.15E-03 14 114 "DRAXIN,SLC30A10,SFMBT2,NSG2,DACH2,TAGLN3,C11orf87,ANO4,PCDH8,PRRX1,CRMP1,NRSN1,TMCC2,KCNK2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.33E-05 3.26E-01 4.91E-04 4.41E-03 16 144 "FABP7,LRRC4C,TMEM108,PALLD,SMOC1,NFIA,ADGRL3,GUCY1A1,PCDH9,DCLK1,PDE1A,FNDC5,PRRX1,PLD5,MAGI2,TMEM255A" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.42E-05 3.30E-01 4.96E-04 4.46E-03 29 364 "EPS8,ACER3,LGR4,FABP7,GRAMD1B,SOX6,DOCK10,CADPS,PALLD,NCAM1,SMOC1,NFIA,PCDH11X,ADGRL3,GPM6B,GRIA4,TGFBR3,GUCY1A1,PCDH9,PDE1A,TMEFF2,SERPINE2,FAT3,TENM4,MICAL2,VCAN,MASP1,PTCH1,TMEM255A" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k3 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.83E-05 3.48E-01 5.23E-04 4.70E-03 20 208 "MBP,MRVI1,CLIP1,APC,ATP1A2,PHYHIPL,DKK3,DNER,NFIA,PLEKHB1,CCSER2,OSBPL3,KCNA1,PTPRZ1,KCNMA1,FAM13C,ABCC9,TTLL7,SSPN,RCAN2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 7.87E-05 3.50E-01 5.25E-04 4.71E-03 26 311 "EMID1,LGR4,CEND1,IL17D,NDRG2,PLEKHG5,ERMN,TUBB4A,CCDC80,CLSTN1,PALLD,JPH4,SALL3,STARD10,INKA2,AJAP1,ROBO3,WWC1,CECR2,INA,CCDC136,NKAIN4,CA10,CDH20,KCNK1,PIANP" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.16E-05 3.62E-01 5.43E-04 4.88E-03 50 779 "ABAT,PRR5L,RIMKLA,CDHR1,RCSD1,ADGRV1,EYA1,FGF1,AMPH,SFPQ,ASRGL1,SGIP1,ANK3,PPM1E,APC,SFMBT2,DACH2,ATP1A2,MYBPC1,FXYD6,NASP,C11orf87,CLASP2,GFRA1,NELL1,CAMTA1,CAMSAP2,WSCD1,B4GALNT4,NRDC,CECR2,ZFP91,RBFOX2,NEGR1,NSD2,FAT3,NXPH1,SNCAIP,VCAN,RBPJ,MAPK8,PTHLH,ITIH2,LRP8,NKAIN1,DTNA,CRTAC1,NUP214,ABI2,ELAVL4" Coexpression Atlas JC_iEC_2500_K1 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#1 PCBC 8.28E-05 3.68E-01 5.50E-04 4.94E-03 45 677 "SLC44A5,SCN3A,BCAR3,BBOX1,FOXG1,CDC42BPA,NLGN1,SLC7A14,MSR1,LRRC55,SLIT1,DLL3,SNAP25,NRG3,SOX1,SOX5,ILDR2,DNER,NELL1,POPDC3,MYRF,ADGRL3,KLHL4,ANO4,TBX15,ZEB1,TCF12,OPCML,TIE1,PCDH9,CDH10,LGI1,TPM4,NMT2,CALY,PKN2,PTCH1,CNIH3,PTPRE,DPP6,RASGRF1,RLBP1,EN2,RPE65,TMEM100" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.37E-05 3.72E-01 5.56E-04 4.99E-03 20 209 "APC,MIER1,SCMH1,DKK3,AHCYL1,NASP,CLASP2,NFIA,CAMSAP2,ADGRL3,GRIA2,ZFP91,RBFOX2,PRRX1,VCAN,RBPJ,MAPK8,PTPRO,TMEM255A,NUP214" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.40E-05 3.73E-01 5.57E-04 5.00E-03 17 161 "LGR4,CCDC80,NCAM1,NFIA,PCDH11X,MYRF,ADGRL3,KLHL4,GUCY1A1,DAAM2,CDH10,DCLK1,PDE1A,PRRX1,ATRNL1,VCAN,TMEM255A" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.56E-05 3.80E-01 5.67E-04 5.09E-03 19 193 "ADGRV1,FABP7,SFPQ,LRRC4C,ASCL1,NASP,RND1,TCF12,HMGB1,JAM2,FAT3,POU3F2,SF1,TENM4,HES5,TOX,PANTR1,RFX4,EN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.88E-05 3.94E-01 5.87E-04 5.27E-03 49 761 "MBP,SYNDIG1,IL17D,MRVI1,NDRG2,F3,FABP7,SORCS1,FHL1,ANK1,PI16,SORBS1,KIAA1614,ATP1A2,DKK3,GABBR1,SCN3B,TNIK,ILDR2,MYH7,DNER,RAP1GAP2,INKA2,NFIA,POPDC3,CAMSAP2,PRUNE2,CAMK2G,ADAMTS8,NEURL1,TNS1,PDE4B,MICAL1,PRRX1,PRKAB2,PSD,PTHLH,KCND3,RABGAP1L,CCDC3,KCNMA1,FAM13C,DTNA,ABCC9,TTLL7,SSPN,SH3GLB1,PLEKHO1,RASGRP2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.93E-05 3.97E-01 5.90E-04 5.29E-03 31 405 "MEG3,ADD3,PNMA8B,FGF1,SFPQ,PKP4,ATP1A2,ZCCHC24,ILDR2,NASP,NFIA,CNDP1,VSTM2A,TNS1,PCDH9,DCLK1,UBTF,NMT2,PRRX1,FAT3,CP,MAPK8,PUM1,FGFR1OP2,PMEPA1,ZC3H11A,KCND3,SNX27,TMEM255A,ABCC9,EPB41L2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.04E-05 4.02E-01 5.96E-04 5.35E-03 12 89 "APC,MIER1,CLASP2,NFIA,ADGRL3,GRIA2,ZFP91,RBFOX2,PRRX1,VCAN,PTPRO,NUP214" Coexpression Atlas gudmap_developingGonad_P2_testes_500_k2 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.16E-05 4.07E-01 6.03E-04 5.41E-03 14 117 "TTYH1,ADCYAP1R1,ADORA1,SH3GL2,SLC1A6,MMD2,VXN,ADGRG1,JAM2,SEMA5B,ARHGEF4,TOX,PTPRE,PLPPR4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200_k5 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.59E-05 4.26E-01 6.30E-04 5.66E-03 5 14 "CDHR1,SGIP1,DACH2,NEGR1,SNCAIP" Coexpression Atlas GSM854326_500 "Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3" "Immgen.org, GSE15907" 9.77E-05 4.34E-01 6.41E-04 5.76E-03 31 407 "ACER3,CSMD3,RTN1,ADORA3,FCGR1A,SLC2A5,ARHGAP5,ASPH,NEK6,ADAM15,C1QC,TF,USP2,P2RX7,TJP1,CD81,ADGRG1,JAM2,ARHGAP22,SERPINE2,P2RY12,CSF3R,CTNND1,SIRPA,PTAFR,PMEPA1,RAB3IL1,RGS10,PLEKHO1,TMEM100,EPB41L2" Coexpression Atlas ratio_DE_vs_SC_1000_K5 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 9.88E-05 4.39E-01 6.48E-04 5.81E-03 38 542 "ACHE,WLS,RXRG,SORCS1,ERMN,BCAR3,MOBP,C1orf61,MAGI3,SLC7A14,SOX5,SOX10,NFASC,FGF17,CASTOR3,NODAL,GPM6A,CCKBR,LEFTY2,PAX6,CDH10,SEZ6L,LGI1,SERPINE2,CADM1,COL9A2,PACSIN1,TENM4,CSF3R,PLPP4,MAPK10,ANKS1B,ELMO1,CDH20,SLC25A48,DSCAM,FAM13C,FAM135B" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500_K2 facebase_RNAseq_e10.5_OlfacPit_2500_K2 Gudmap RNAseq 1.01E-04 4.48E-01 6.60E-04 5.93E-03 12 90 "MAP6,MAPT,ACHE,ADGRV1,SNAP25,INKA2,GRIK2,CELF3,CA14,TMEFF2,MICAL2,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.02E-04 4.52E-01 6.65E-04 5.97E-03 16 148 "MEG3,NDRG2,FABP7,PALLD,NCAM1,PCDH11X,ADGRL3,GRIA4,GUCY1A2,GUCY1A1,PCDH9,HPSE2,FAT3,VCAN,PTCH1,TMEM255A" Coexpression Atlas GSM605868_500 "Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4" "Immgen.org, GSE15907" 1.02E-04 4.54E-01 6.67E-04 5.98E-03 31 408 "EPS8,PRR5L,ACER3,LDLRAD3,RTN1,FCGR1A,FGR,MSR1,CCDC88A,ATP1A3,ZCCHC24,ADAM15,RAP1GAP2,TF,TNFRSF1B,TPD52,ZFYVE9,CSF3R,ATRNL1,VCAN,DOCK7,SDC3,CTNND1,KIAA0513,SIRPA,PTAFR,PTPRO,PID1,ARHGEF10L,VWA5A,PLEKHO1" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500 facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500 Gudmap RNAseq 1.04E-04 4.63E-01 6.79E-04 6.09E-03 89 1641 "RABEPK,TTYH1,SERPINA3,ABAT,PRR5L,EMID1,EXTL1,CEND1,RTKN,NDRG2,F3,ADCY2,FOXRED2,CHST15,TESK2,PDZD4,SOX6,TRIM46,SEMA6C,CNIH2,ANXA7,PPM1E,APBB1,DOCK10,NTNG1,CCDC80,KIAA1614,SLC6A9,YPEL4,GPR153,TAGLN3,NRG3,PALLD,DKK3,SOX5,ZCCHC24,CADM3,ADGRB2,NCAM1,COLGALT2,RCOR2,NELL1,PHLDB1,NFIA,C1QC,DCLK2,ATF7,B4GALNT4,NRGN,AZIN2,DDR2,TF,P2RX7,GUCY1A1,CELF3,DAAM2,REPS2,TNS1,DCLK1,NLGN3,SERPINE2,CADM1,NRXN1,NEGR1,PIK3CD,CPT1C,FTO,PRRX1,CNRIP1,SNCAIP,TENM4,FEZ1,SDC3,ECE2,ZBTB16,TOX,ZNF385B,LRRTM3,SHD,PTPRD,KCNA6,PTPRO,SV2A,RAB3IL1,RAP1GAP,SSPN,EFNA3,EPB41L2,RCAN2" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.06E-04 4.69E-01 6.87E-04 6.17E-03 53 850 "PRR5L,CDHR1,EYA1,RYR1,DRAXIN,SLC30A10,AMPH,ASRGL1,DOCK10,NTNG1,JAKMIP3,SFMBT2,PKNOX2,NSG2,DACH2,TAGLN3,ASTN1,ATP1A2,ATP2B2,GABBR1,KIF21B,EMC1,FXYD6,C11orf87,GFRA1,NELL1,ANO4,B4GALNT4,PTBP2,AKNA,GRM3,PADI2,PCDH8,CA14,CADM1,PMS2,PRRX1,NSD2,SF1,CRMP1,NRSN1,ECE2,ZBTB16,GON4L,LRP8,SMG7,TMCC2,KCNK2,NKAIN1,USH1C,VANGL2,EFNA3,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.10E-04 4.88E-01 7.14E-04 6.41E-03 22 247 "GALNT13,LRRTM4,ZNF365,SON,DNER,UNC5D,ADGRL3,TBX15,DDR2,PSD3,GRIA2,PCDH8,DCLK1,NLGN3,PRRX1,MAPK8,TOX,MAGI2,KCNA4,TMEM255A,PARP11,CBLN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.10E-04 4.90E-01 7.15E-04 6.42E-03 16 149 "KIAA1109,ANK3,APC,SMOC1,GFRA1,NFIA,PCDH11X,CAMSAP2,GRIA2,RBFOX2,PRRX1,FAT3,VCAN,ELMO1,ARNT2,NUP214" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.12E-04 4.99E-01 7.27E-04 6.53E-03 12 91 "EYA1,DNER,UNC5D,ADGRL3,TBX15,DDR2,GRIA2,PCDH8,DCLK1,PRRX1,TOX,MAGI2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K4 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.12E-04 5.00E-01 7.27E-04 6.53E-03 19 197 "EPS8,ACTN2,ADCY2,SLC1A2,SLC6A9,ARPP21,ADGRB2,NELL1,ACSBG1,C1QC,UNC5D,ADGRL3,REPS2,NXPH1,CADM2,LRP8,PCDH15,DLG2,EPB41L1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k1 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.13E-04 5.01E-01 7.27E-04 6.53E-03 9 53 "SMOC1,GFRA1,NFIA,CAMSAP2,GRIA2,RBFOX2,PRRX1,FAT3,NUP214" Coexpression Atlas ratio_DE_vs_SC_500_K5 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 1.13E-04 5.01E-01 7.27E-04 6.53E-03 25 300 "RXRG,SORCS1,ERMN,MOBP,C1orf61,SLC7A14,DKK3,SOX5,NFASC,FGF17,NODAL,CCKBR,LEFTY2,CDH10,SEZ6L,SERPINE2,CADM1,COL9A2,PACSIN1,TENM4,CSF3R,FMN2,PLPP4,ANKS1B,PMEPA1" Coexpression Atlas ratio_MESO_vs_SC_1000_K5 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 1.14E-04 5.06E-01 7.32E-04 6.57E-03 35 487 "WLS,CSMD3,RXRG,SORCS1,ADORA1,MOBP,C1orf61,ST8SIA1,SLC1A2,SOX10,NFASC,FGF17,CASTOR3,NODAL,MYRF,GPM6A,GRIK3,OLR1,CCKBR,LEFTY2,PAX6,PCDH8,SEZ6L,SERPINE2,COL9A2,TENM4,FMN2,PLPP4,MAPK10,ANKS1B,CDH20,KCNH1,DSCAM,FAM135B,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.14E-04 5.06E-01 7.32E-04 6.57E-03 17 165 "SCN3A,SGIP1,DACH2,MYH7,SMOC1,GFRA1,NFIA,CAMSAP2,GRIA2,GRM3,CDH10,RBFOX2,PRRX1,FAT3,JAKMIP2,CALN1,NUP214" Coexpression Atlas ratio_SC_vs_EB_2500_K5 ratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 1.17E-04 5.19E-01 7.50E-04 6.73E-03 59 981 "RIMKLA,ADCY2,RYR1,NLGN4X,DRAXIN,SEMA6A,CNIH2,BCAN,JAKMIP3,SHANK2,SCG3,SLCO1A2,DDX25,IGSF9B,SNCB,JPH4,SALL3,LHFPL4,NAP1L2,NASP,NCDN,RCOR2,LUZP2,GNG4,UNC5D,KLHL4,B4GALNT4,GPR19,SYT6,TLL2,ZDHHC22,PAH,IGSF21,C1orf94,HRH3,CIART,CHGA,DLGAP3,CAMKV,TJP2,PACSIN1,BTBD17,KCNT2,RIMS4,RAB39A,IGSF1,TUBB2B,LRRTM3,JAKMIP2,CADM2,PARD6A,PTPRZ1,RABGAP1L,SLC25A18,ST8SIA3,SFXN5,FGFBP3,C2orf80,SEZ6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.21E-04 5.36E-01 7.73E-04 6.94E-03 14 120 "EYA1,SGIP1,NTNG1,DACH2,NPAS3,FBXL16,ZFP91,DCLK1,TENM4,FMN2,LRRTM3,KCNA6,PTPRZ1,NTM" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.21E-04 5.38E-01 7.75E-04 6.96E-03 23 266 "MEG3,ADCY2,FABP7,GPAM,LRRC4C,PKNOX2,PALLD,NCAM1,NFIA,MYRF,PSD3,GUCY1A2,GUCY1A1,PCDH9,LGI1,HPSE2,PRRX1,FAT3,TENM4,ATRNL1,VCAN,PRKACB,TMEM255A" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Lungmap CCHMC 1.22E-04 5.42E-01 7.79E-04 6.99E-03 32 431 "ABAT,LGR4,MEG3,LDLRAD3,NDRG2,F3,ADCY2,AGT,APBB1,NLGN1,USP16,ATP1A2,PALLD,DKK3,SOX5,KIF1B,PHLDB1,CACNB2,DDR2,TGFBR3,GUCY1A1,NEURL1,DCLK1,HPSE2,SERPINE2,CPT1C,COL9A2,TENM4,PTCH1,PMEPA1,KCNMA1,TMEM100" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.22E-04 5.42E-01 7.79E-04 6.99E-03 32 431 "PRR5L,CDHR1,EYA1,RYR1,DRAXIN,AMPH,NSG2,DACH2,TAGLN3,ASTN1,ATP1A2,C11orf87,GFRA1,NELL1,ANO4,B4GALNT4,PTBP2,AKNA,GRM3,PCDH8,CA14,SF1,CRMP1,NRSN1,ECE2,LRP8,SMG7,KCNK2,NKAIN1,USH1C,EFNA3,ELAVL4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.23E-04 5.45E-01 7.82E-04 7.02E-03 18 182 "ACER3,NDRG2,ADCY2,ADCYAP1R1,FABP7,GPAM,PKNOX2,NCAM1,GRIA4,TGFBR3,GUCY1A1,PCDH9,TMEFF2,FAT3,MICAL2,VCAN,PTCH1,KCND3" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-OSKM - NLT_cfr-2X-p05 Mesoderm Day 30-reprogram_NA_vs_Mesoderm Day 30-reprogram_OSKM - NLT-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.25E-04 5.54E-01 7.90E-04 7.09E-03 29 375 "TTYH1,SERPINA3,MAPT,MBP,PAQR6,F3,RTN1,AGT,NSG2,SLIT1,ATP1A3,KIF21B,DNER,RAP1GAP2,GJB1,ROBO3,GPM6A,CELF3,GDAP1L1,COL9A2,ATCAY,CP,IGSF1,ITIH2,STMN4,PANTR1,RAP1GAP,USH1C,ELAVL3" Coexpression Atlas PCBC_ratio_MESO-30 blastocyst_vs_MESO-30 fibroblast_cfr-2X-p05 MESO-30 blastocyst_vs_MESO-30 fibroblast-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.25E-04 5.54E-01 7.90E-04 7.09E-03 29 375 "TTYH1,SERPINA3,MAPT,MBP,PAQR6,F3,RTN1,AGT,NSG2,SLIT1,ATP1A3,KIF21B,DNER,RAP1GAP2,GJB1,ROBO3,GPM6A,CELF3,GDAP1L1,COL9A2,ATCAY,CP,IGSF1,ITIH2,STMN4,PANTR1,RAP1GAP,USH1C,ELAVL3" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-plasmid_cfr-2X-p05 Mesoderm Day 30-method_NA_vs_Mesoderm Day 30-method_plasmid-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.25E-04 5.54E-01 7.90E-04 7.09E-03 29 375 "TTYH1,SERPINA3,MAPT,MBP,PAQR6,F3,RTN1,AGT,NSG2,SLIT1,ATP1A3,KIF21B,DNER,RAP1GAP2,GJB1,ROBO3,GPM6A,CELF3,GDAP1L1,COL9A2,ATCAY,CP,IGSF1,ITIH2,STMN4,PANTR1,RAP1GAP,USH1C,ELAVL3" Coexpression Atlas ratio_SC_vs_DE_500_K3 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 1.25E-04 5.55E-01 7.90E-04 7.09E-03 7 32 "ELMOD1,TMEM151A,DNER,LMO3,SNCAIP,NKAIN4,PTPRO" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.25E-04 5.56E-01 7.90E-04 7.09E-03 12 92 "SERPINA3,IL17D,SLC14A1,PHYHIPL,DNER,PDE4B,PTHLH,KCNA1,PTPRZ1,FAM13C,ABCC9,TTLL7" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.25E-04 5.56E-01 7.90E-04 7.09E-03 12 92 "ADGRV1,NDRG2,NTNG1,CCDC80,PCDH11X,GRIK2,PAX6,PCDH9,NECAB2,FEZ1,FMN2,TOX" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.28E-04 5.69E-01 8.08E-04 7.26E-03 42 629 "RTN3,ARID1A,CLIP1,WAC,KIAA1109,PKP4,APC,NTNG1,NLGN1,MSR1,ARHGAP5,PDE8B,ASTN1,SON,CAB39,NASP,LMO3,ARHGEF7,GOLGB1,ZEB1,PTBP2,GUCY1A2,CDK11B,PAX6,PCDH9,CDH8,PDE1A,HMGB1,ZFYVE9,KIAA1549L,SEMA5B,PLCH2,FMN2,TOX,JAKMIP2,LRP8,CEP170,ZC3H11A,NKAIN1,ZYG11B,RFX4,EPB41L1" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_100 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_100 FaceBase_ST1 1.31E-04 5.82E-01 8.26E-04 7.41E-03 9 54 "MT3,NKX6-2,FGF17,MFSD2A,JAM2,FAM181B,POU3F4,HES5,EN2" Coexpression Atlas Arv_SC-H9hpx_500_K1 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 1.32E-04 5.87E-01 8.30E-04 7.45E-03 21 233 "ADCY2,FABP7,NLGN4X,PDZD4,SCG3,DDX25,B3GAT1,SALL3,LHFPL4,PCDH11X,SYT6,GRIA4,CHGA,CAMKV,BTBD17,KCNT2,RIMS4,RAB39A,CADM2,KCNQ2,DPP6" Coexpression Atlas Arv_SC-hpx_blastocyst_500_K5 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 1.32E-04 5.87E-01 8.30E-04 7.45E-03 21 233 "ADCY2,FABP7,NLGN4X,PDZD4,SCG3,DDX25,B3GAT1,SALL3,LHFPL4,PCDH11X,SYT6,GRIA4,CHGA,CAMKV,BTBD17,KCNT2,RIMS4,RAB39A,CADM2,KCNQ2,DPP6" Coexpression Atlas GSM476678_500 "gamma delta T cells, Tgd.vg2+.act.Sp, TCRd+ Vg2+ CD44+, Spleen, avg-3" "Immgen.org, GSE15907" 1.32E-04 5.88E-01 8.30E-04 7.45E-03 30 395 "GRAMD1B,SELL,RASA3,PKP4,GAS7,NSG2,SLC14A1,FYN,TNIK,KIF21B,B4GALNT1,ACSBG1,SEMA4A,AKNA,PADI2,PDE2A,PDE3B,PIK3CD,OSBPL3,PRKCZ,TOX,SYTL2,KCNK1,NAV2,KLRC2,KLRC3,ATN1,RET,RAVER2,RASGRP2" Coexpression Atlas facebase_RNAseq_e10.5_MaxArch_2500 facebase_RNAseq_e10.5_MaxArch_2500 Gudmap RNAseq 1.35E-04 6.02E-01 8.49E-04 7.62E-03 87 1608 "ACER3,ACHE,ACLY,CEND1,EYA1,MRVI1,ARID1A,CLIP1,WAC,SEMA6A,SELL,SFPQ,SGIP1,SH3GL2,APC,ST3GAL3,ST8SIA1,BCAS1,RUFY2,PKNOX2,ARHGAP5,CCDC88A,SLC14A1,ASPH,SMARCE1,SNAP25,ATM,TMEM151A,TNIK,SOX5,MYH7,RAP1GAP2,NASP,INKA2,RND1,SEPT3,ACSBG1,ZNF638,CACNA1A,CACNB2,ZEB1,CLEC9A,TCF12,NRGN,HAP1,PTBP2,EML4,CECR2,GRIK2,MFSD2A,GUCY1A2,DAAM2,CDK11B,TPM4,PDE1C,PDE3B,ADGRG1,CA14,HPCA,ARHGAP22,CABP1,PRRX1,CP,SNCAIP,FEZ1,VCAN,DOCK7,DZIP3,MAPK8,FGFR1OP2,TOX,ZNF385B,DNAJC6,ITIH2,LRP8,KCNC1,NKAIN1,KIF2A,RAP1GAP,DTNA,L1CAM,ABCC9,SSPN,LPAR6,ELAVL4,PLEKHO1,EPB41" Coexpression Atlas JC_iEC_1000 JC_iEC_top-relative-expression-ranked_1000 PCBC 1.37E-04 6.11E-01 8.60E-04 7.72E-03 59 987 "CDHR1,EMID1,FAM43B,F3,PLEKHG5,ADCY2,GALNT13,SLC44A5,SCN3A,BBOX1,FOXG1,SELL,PI16,SLC7A14,MSR1,LRRC55,TMEM108,NRG3,SOX1,ILDR2,DNER,NCAM1,NELL1,RHBDL3,PCDH11X,POPDC3,GNG4,MYRF,KLHL4,ANO4,TBX15,CACNA1E,VWC2,HAP1,SYT6,VWCE,OPCML,TIE1,TLL2,NEURL1,ZDHHC22,MAEL,PCDH9,CDH10,LGI1,PDE3B,FNDC5,JAM2,LRRTM3,PTHLH,CNIH3,PTPRE,KCND3,PCDH15,DPP6,EN2,RPE65,TMEM100,SEZ6" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.39E-04 6.16E-01 8.66E-04 7.78E-03 22 251 "LGR4,RASA3,SESN3,CACHD1,SCMH1,PDE8B,MTR,PCDH11X,ADGRL3,CACNB2,TCF12,GRIK3,DAAM2,DCLK1,MAGI1,PDE1A,FNDC5,CHRM4,PLD5,MAGI2,NAV2,EPB41L1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.39E-04 6.18E-01 8.68E-04 7.79E-03 8 43 "IL17D,SLC14A1,PDE4B,KCNA1,PTPRZ1,FAM13C,ABCC9,TTLL7" Coexpression Atlas PCBC_MESO-5_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 1.44E-04 6.41E-01 8.99E-04 8.07E-03 35 493 "ADGRV1,RXRG,SORCS1,ADORA1,UNC79,C1orf61,PDZD4,SCG3,B3GAT1,SOX10,SALL3,FGF17,NODAL,MYRF,GPM6A,GRIK3,CCKBR,PTPN5,LEFTY2,USP2,CDH8,SEZ6L,CA14,SEMA5B,A2ML1,COL9A2,PACSIN1,ETNPPL,FMN2,ANKS1B,CADM2,KCNQ2,SLC25A48,USH1C,ELAVL4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.45E-04 6.46E-01 9.05E-04 8.12E-03 26 323 "ADD3,ELMOD1,ASRGL1,SLC1A6,SPHKAP,JPH4,NEK6,ADGRB2,NASP,SPART,C11orf87,PCDH11X,MYRF,GPM6B,B4GALNT4,RBFOX2,ARHGAP19,MAGI1,PDE1A,ZBED5,TMEFF2,NMT2,GON4L,PLPPR5,ITGAV,AK5" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.55E-04 6.91E-01 9.66E-04 8.67E-03 50 800 "MEG3,NDRG2,ADD3,PNMA8B,KIAA1109,FGF1,SEMA6C,SFPQ,PKP4,SCMH1,ARFGAP1,RCOR3,ATP1A2,TNIK,ZCCHC24,ILDR2,KIF1B,NASP,NFIA,BTRC,CNDP1,KLHL4,GPM6A,TCF7L2,VSTM2A,TNS1,PCDH9,DCLK1,RBFOX2,UBTF,NMT2,PRRX1,FAT3,CP,FEZ1,DZIP3,MAPK8,PUM1,FGFR1OP2,ZBTB16,ZNF385B,PMEPA1,ZC3H11A,KCND3,NAV2,SNX27,TMEM255A,ABCC9,JMJD1C,EPB41L2" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K5 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 1.56E-04 6.94E-01 9.69E-04 8.70E-03 15 138 "TTYH1,ATAT1,SLC30A10,LRRC4C,NPAS3,HPSE2,DPYSL5,CA10,STMN4,PCDH15,DNAH9,SLC17A6,BEND5,PAK5,EN2" Coexpression Atlas gudmap_developingGonad_e11.5_testes_500 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.57E-04 6.98E-01 9.73E-04 8.73E-03 32 437 "MAPT,ACLY,MEG3,ARID1A,FABP7,LINC00461,SFPQ,TAGLN3,DLL3,SON,ZCCHC24,NASP,SPART,NCAM1,OS9,BTRC,KLHL4,DDR1,CAMK2G,INA,ZMYND8,CRMP1,RNF14,PRKACB,PUM1,TUBB2B,BLOC1S6,RTN4,RFX4,VANGL2,ELAVL4,EPB41L2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.57E-04 6.98E-01 9.73E-04 8.73E-03 14 123 "MEG3,ADCY2,GPAM,LRRC4C,PALLD,NCAM1,NFIA,PSD3,GUCY1A1,PCDH9,PRRX1,ATRNL1,VCAN,TMEM255A" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K2 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.64E-04 7.27E-01 1.01E-03 9.08E-03 32 438 "MBP,ATAT1,GRAMD1B,LRRTM4,PPM1E,SESN3,NSG2,B3GAT1,SNAP25,CCDC181,NEK6,NFIA,DCLK2,DDHD2,CAMTA1,DIRAS1,HAP1,CAMK2A,MFSD2A,CELF3,ATG4C,DCLK1,ADGRG1,GDAP1L1,FADS2,ACBD5,NCAN,PRKCZ,RAB5B,PARP11,CAMK1G,OLIG2" Coexpression Atlas GSM605886_500 "Myeloid Cells, Mo.6C-IIint.Bl, CD115+ B220- CD43- Ly6C- MHCIIint, Blood, avg-5" "Immgen.org, GSE15907" 1.65E-04 7.32E-01 1.02E-03 9.13E-03 30 400 "EPS8,PRR5L,ACER3,LDLRAD3,RTN1,FCGR1A,FGR,MSR1,CCDC88A,ASPH,ATP1A3,RAP1GAP2,TCF7L2,TF,TGFBR3,ATG4C,TNFRSF1B,TPD52,ZFYVE9,CSF3R,DOCK7,SDC3,ZBTB16,KIAA0513,SIRPA,ITGAV,PTPRE,PID1,L1CAM,ARHGEF10L" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_200_k4 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.66E-04 7.37E-01 1.02E-03 9.18E-03 10 68 "ABAT,MRVI1,SLC14A1,DACH2,DNER,ANO4,GRIA1,LGI1,NEGR1,CNTN1" Coexpression Atlas facebase_RNAseq_e9.5_MandArch_2500_K2 facebase_RNAseq_e9.5_MandArch_2500_K2 Gudmap RNAseq 1.75E-04 7.77E-01 1.08E-03 9.66E-03 9 56 "SOX6,SLIT1,SOX5,NASP,ACSBG1,CAMK2A,CECR2,GRIK2,PDE3B" Coexpression Atlas GSM605883_500 "Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 1.80E-04 7.98E-01 1.10E-03 9.91E-03 30 402 "EPS8,ACER3,LDLRAD3,RTN1,FCGR1A,FGR,CCDC88A,ASPH,ATP1A3,RAP1GAP2,TCF7L2,TF,TGFBR3,ATG4C,TNFRSF1B,TPD52,ZFYVE9,CSF3R,PRKAB2,DOCK7,SDC3,CTNND1,ZBTB16,KIAA0513,SIRPA,ITGAV,PTPRE,PID1,L1CAM,ARHGEF10L" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.85E-04 8.21E-01 1.13E-03 1.02E-02 18 188 "MEG3,NTNG1,MTR,ADGRL3,KLHL4,DDR2,GRIA1,GRIA4,REPS2,CDH10,FTO,RNF14,PTPRD,SRGAP3,NTM,RTN4,SSPN,VWA5A" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_1000 DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.86E-04 8.25E-01 1.14E-03 1.02E-02 50 806 "ACTN2,MEG3,ARID1A,PNMA8B,CHST15,SOX6,SEMA6C,SFPQ,PKP4,GAS7,SYBU,PKNOX2,SCMH1,ASPH,MTR,FYN,SOX5,ZCCHC24,KIF1B,NASP,RGL1,ADHFE1,NFIA,ZNF638,NODAL,MMD2,BTRC,KLHL4,TCF7L2,LEFTY2,GUCY1A1,MAEL,TNS1,PCDH9,CDH10,UBTF,NMT2,TENM4,DZIP3,MAPK8,PUM1,FGFR1OP2,ZC3H11A,PTPRE,KCNH1,NAV2,SNX27,TMEM255A,DTNA,EPB41L2" Coexpression Atlas GSM538332_500 "alpha beta T cells, NKT.44+NK1.1+.Th, aGC CD1d tet CD3e CD44 NK1.1, Thymus, avg-3" "Immgen.org, GSE15907" 1.95E-04 8.68E-01 1.19E-03 1.07E-02 29 385 "GRAMD1B,SESN3,ST8SIA1,TNIK,B4GALNT1,ACSBG1,SEMA4A,B4GALNT4,TF,TJP1,PADI2,PDE2A,PDE3B,CIART,PACSIN1,CRMP1,OSBPL3,PRKCZ,ZBTB16,TOX,SYTL2,PMEPA1,SRGAP3,KLRC2,KLRC3,ATN1,L1CAM,LPAR6,RAVER2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.95E-04 8.68E-01 1.19E-03 1.07E-02 29 385 "MEG3,CLIP1,KIAA1109,ANK3,APC,DGKD,SON,AHCYL1,KIF1B,NASP,CLASP2,GFRA1,RGL1,NFIA,CAMSAP2,ADGRL3,GRIA2,RBFOX2,PRRX1,FAT3,CNRIP1,MED1,TENM4,VCAN,MAPK8,PUM1,ARNT2,KIF2A,NUP214" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.95E-04 8.68E-01 1.19E-03 1.07E-02 29 385 "EPS8,ACTN2,ADCY2,DOCK10,SLC1A2,SLC6A9,TNIK,ARPP21,ADGRB2,NELL1,NFIA,C1QC,GNG4,UNC5D,ADGRL3,CLEC9A,REPS2,COL9A2,PRRX1,NXPH1,PMEPA1,CADM2,CCDC3,PCDH15,DLG2,BEND5,ABCC9,VWA5A,EPB41L1" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 2.02E-04 8.99E-01 1.23E-03 1.11E-02 17 173 "SLITRK1,LINC00461,FOXG1,ASTN1,ATP2B2,LMO3,PCDH11X,GPM6A,HAP1,GRIK2,MFSD2A,PAX6,ADGRG1,TJP2,JAKMIP2,STMN4,ELAVL4" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.03E-04 9.02E-01 1.24E-03 1.11E-02 14 126 "MEG3,FABP7,PKNOX2,TMEM108,PALLD,NCAM1,MYRF,GUCY1A1,TMEFF2,PRRX1,TENM4,MICAL2,ATRNL1,VCAN" Coexpression Atlas GSM605811_500 "gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3" "Immgen.org, GSE15907" 2.04E-04 9.07E-01 1.24E-03 1.11E-02 30 405 "WLS,GRAMD1B,FGR,SESN3,STK32C,CLSTN1,FYN,TNIK,ACSBG1,OS9,B4GALNT4,PTPN5,P2RX7,TNFRSF1B,PADI2,PDE3B,ACOT7,ADGRG1,OSBPL3,PRKACB,TOX,SYTL2,DNAJC6,ITGAV,PMEPA1,SRGAP3,RABGAP1L,SUSD4,FAM135B,EPB41" Coexpression Atlas GSM538245_500 "Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 2.22E-04 9.88E-01 1.35E-03 1.21E-02 30 407 "EPS8,PRR5L,RTN1,SCN3A,FGR,ST8SIA1,STK32C,SHTN1,CCDC88A,ATP1A3,CADM3,RGL1,ADGRL3,CLEC9A,HAP1,TF,TNS1,PFKFB3,ATRNL1,DOCK7,SDC3,CTNND2,SPIRE1,SIRPA,PTAFR,PTPRO,PID1,DSCAM,JMJD1C,PLEKHO1" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.22E-04 9.88E-01 1.35E-03 1.21E-02 30 407 "MEG3,ADD3,PNMA8B,SFPQ,PKP4,SCMH1,MYBPC1,ZCCHC24,ILDR2,NASP,NFIA,PCDH11X,KLHL4,VSTM2A,TNS1,PCDH9,DCLK1,NMT2,PRRX1,FAT3,MAPK8,PUM1,FGFR1OP2,PMEPA1,ZC3H11A,KCND3,NAV2,SNX27,TMEM255A,EPB41L2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.23E-04 9.90E-01 1.35E-03 1.21E-02 29 388 "MBP,IL17D,MRVI1,NDRG2,FHL1,ANK1,PI16,SORBS1,ATP1A2,DKK3,SCN3B,TNIK,MYH7,DNER,POPDC3,PRUNE2,NEURL1,TNS1,MICAL1,PSD,PTHLH,KCND3,RABGAP1L,FAM13C,DTNA,ABCC9,TTLL7,SH3GLB1,PLEKHO1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500_2 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500_2 FaceBase_ST1 2.24E-04 9.93E-01 1.35E-03 1.21E-02 21 242 "APBA2,MT3,CCDC88A,PHYHIPL,SEPT3,WSCD1,TCF12,USP2,INA,PAX6,IGSF21,PCDH9,NMT2,FAT3,FEZ1,ZBTB16,TUBB2B,JAKMIP2,COPS7A,LMO1,ROM1" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.25E-04 1.00E+00 1.36E-03 1.22E-02 18 191 "ABAT,LGR4,RASA3,SESN3,CCDC80,ST8SIA1,SCMH1,SOX5,SMOC1,NFIA,PCDH11X,ADGRL3,CACNB2,DCLK1,MAGI1,FNDC5,CHRM4,NAV2" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.27E-04 1.00E+00 1.37E-03 1.23E-02 7 35 "MRVI1,DACH2,DKK3,ANO4,NEGR1,CNTN1,KCND3" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.28E-04 1.00E+00 1.37E-03 1.23E-02 19 208 "FABP7,LRRC4C,PKNOX2,PALLD,ZCCHC24,NCAM1,MYRF,GUCY1A2,GUCY1A1,CDH10,TMEFF2,PRRX1,FAT3,TENM4,MICAL2,ATRNL1,VCAN,SYTL2,SV2A" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_100 kidney_P2_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.29E-04 1.00E+00 1.38E-03 1.23E-02 11 84 "EYA1,AMPH,NCAM1,GFRA1,NELL1,CADM1,FAT3,SNCAIP,VCAN,ELAVL4,TMEM100" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.30E-04 1.00E+00 1.38E-03 1.24E-02 12 98 "SCG3,PHYHIPL,ILDR2,GNG3,WWC1,PAX6,KIAA1549L,NECAB2,PLCH2,CTNND2,ELAVL4,EPB41" Coexpression Atlas GSM605802_500 "gamma delta T cells, Tgd.vg5+.act.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 2.52E-04 1.00E+00 1.51E-03 1.36E-02 30 410 "PRR5L,WLS,GRAMD1B,FGR,SESN3,STK32C,CLSTN1,FYN,TNIK,ACSBG1,KLHL4,B4GALNT4,P2RX7,TNFRSF1B,PADI2,PDE3B,ACOT7,ADGRG1,FADS2,PPP2R5C,OSBPL3,PRKACB,TOX,SYTL2,DNAJC6,PMEPA1,SRGAP3,RABGAP1L,KCNK1,SUSD4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.53E-04 1.00E+00 1.51E-03 1.36E-02 16 160 "CDHR1,EYA1,FGF1,AMPH,SGIP1,DACH2,ATP1A2,GFRA1,NELL1,NEGR1,FAT3,NXPH1,SNCAIP,ITIH2,LRP8,ELAVL4" Coexpression Atlas JC_iEC_1000_K5 JC_iEC_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.53E-04 1.00E+00 1.51E-03 1.36E-02 28 372 "F3,PLEKHG5,SLC44A5,BBOX1,FOXG1,LRRC55,NRG3,SOX1,ILDR2,DNER,NELL1,POPDC3,MYRF,KLHL4,ANO4,TBX15,CACNA1E,OPCML,NEURL1,PCDH9,CDH10,LGI1,PTHLH,CNIH3,DPP6,EN2,RPE65,TMEM100" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 2.65E-04 1.00E+00 1.58E-03 1.42E-02 8 47 "DLL3,ATP1A3,ARPP21,C11orf87,ACSBG1,CLEC9A,IGSF1,SEZ6" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_k1_200 kidney_P4_CapMesRenVes_Crym_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.65E-04 1.00E+00 1.58E-03 1.42E-02 8 47 "EYA1,NCAM1,GFRA1,CECR2,CADM1,SNCAIP,VCAN,TMEM100" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K1 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 2.69E-04 1.00E+00 1.60E-03 1.44E-02 10 72 "ERMN,PHYHIPL,ILDR2,WWC1,WSCD1,PAX6,NECAB2,RFX4,ELAVL4,EPB41" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K1 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 2.70E-04 1.00E+00 1.60E-03 1.44E-02 15 145 "ERMN,TUBB4A,MOBP,TMEM108,JPH4,SALL3,AJAP1,CECR2,INA,PDE1A,ZBTB16,CA10,CDH20,ST8SIA3,SEZ6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.73E-04 1.00E+00 1.62E-03 1.46E-02 7 36 "EYA1,SORCS1,SCN3A,SGIP1,DACH2,NAP1L2,NPAS3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.75E-04 1.00E+00 1.63E-03 1.46E-02 27 355 "MEG3,ADCY2,FABP7,LRRC4C,PKNOX2,SMARCE1,TMEM108,PALLD,ZCCHC24,NCAM1,NFIA,MYRF,B4GALNT4,DDR2,PSD3,TGFBR3,GUCY1A2,GUCY1A1,CDH10,TMEFF2,PRRX1,FAT3,TENM4,ATRNL1,VCAN,SYTL2,SV2A" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_100 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_100 FaceBase_RNAseq 2.78E-04 1.00E+00 1.65E-03 1.48E-02 12 100 "RTN1,LINC00461,FOXG1,ASCL1,GAD2,FGF17,GPM6A,INA,PAX6,DPYSL5,ELAVL4,OLIG2" Coexpression Atlas GSM605878_500 "Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2" "Immgen.org, GSE15907" 2.85E-04 1.00E+00 1.69E-03 1.51E-02 30 413 "EPS8,PRR5L,ACER3,LDLRAD3,RTN1,FCGR1A,FGR,SHTN1,ATP1A3,ADAM15,RAP1GAP2,C1QC,DDR1,CLEC9A,TF,TNFRSF1B,PADI2,TPD52,ZFYVE9,CSF3R,DOCK7,SDC3,CTNND1,KIAA0513,SIRPA,PTAFR,PTPRO,PID1,L1CAM,PLEKHO1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.91E-04 1.00E+00 1.72E-03 1.54E-02 16 162 "LGR4,CCDC80,NCAM1,SMOC1,PCDH11X,MYRF,ADGRL3,KLHL4,GUCY1A1,CDH10,PDE1A,PRRX1,TENM4,ATRNL1,VCAN,TMEM255A" Coexpression Atlas gudmap_RNAseq_e15.5_Mesangium_2500_K3 gudmap_RNAseq_e15.5_Mesangium_2500_K3 Gudmap RNAseq 2.95E-04 1.00E+00 1.74E-03 1.56E-02 21 247 "ABAT,EMID1,RCSD1,MRVI1,PI16,DOCK10,CCDC80,SORBS1,ZCCHC24,RGL1,GUCY1A1,CD81,PDE1A,TMEFF2,MICAL2,SDC3,ACY3,KCND3,PYGM,ABCC9,RASGRP2" Coexpression Atlas GSM538265_500 "Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 3.00E-04 1.00E+00 1.77E-03 1.58E-02 29 395 "EPS8,RTN1,SCN3A,FGR,DOCK10,ST8SIA1,STK32C,SHTN1,CCDC88A,ATP1A3,CADM3,RGL1,ADGRL3,GPM6B,DDR1,CLEC9A,HAP1,CYB561A3,TNS1,ZFYVE9,DOCK7,SDC3,CTNND2,SPIRE1,SIRPA,PTAFR,PID1,DSCAM,PLEKHO1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_500 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_500 FaceBase_ST1 3.00E-04 1.00E+00 1.77E-03 1.58E-02 29 395 "DPF1,TTYH1,FABP7,LINC00461,SESN3,SCG3,CSPG5,TAGLN3,CAB39,NAP1L2,NPAS3,NEUROD1,GPM6A,PTBP2,MFSD2A,PAX6,PRMT8,ADGRG1,JAM2,FAM181B,NKAIN4,FEZ1,TUBB2B,PTPRZ1,SRGAP3,OLIG1,GOPC,ELAVL4,OLIG2" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.04E-04 1.00E+00 1.79E-03 1.61E-02 49 802 "MEG3,ADD3,PNMA8B,KIAA1109,SEMA6C,SFPQ,PKP4,SCMH1,ARFGAP1,ASPH,MYBPC1,ZCCHC24,ILDR2,KIF1B,NASP,NCAM1,RGL1,NFIA,PCDH11X,C1QC,BTRC,KLHL4,TCF7L2,VSTM2A,GUCY1A1,MAEL,TNS1,PCDH9,RBFOX2,UBTF,NMT2,FLRT1,PMS2,PRRX1,FAT3,TENM4,DZIP3,MAPK8,PUM1,FGFR1OP2,PMEPA1,ZC3H11A,KCND3,NAV2,SNX27,TMEM255A,SUSD4,JMJD1C,EPB41L2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_250 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_250 FaceBase_ST1 3.09E-04 1.00E+00 1.82E-03 1.63E-02 18 196 "TTYH1,FABP7,LINC00461,SCG3,CSPG5,NPAS3,NEUROD1,GPM6A,MFSD2A,PAX6,PRMT8,JAM2,FAM181B,FEZ1,TUBB2B,OLIG1,GOPC,ELAVL4" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_cfr-2X-p05 Pluripotent Stem Cells_vs_Ectoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.12E-04 1.00E+00 1.83E-03 1.64E-02 54 910 "RABEPK,NDRG2,ADCY2,NLGN4X,SEMA6A,RASA3,USP28,SORBS1,SLC6A9,SCG3,ATP1A3,TNIK,JPH4,MIR4697HG,GART,RAP1GAP2,NASP,SEPT3,RHBDL3,GNG4,WWC1,KLHL4,GPM6B,DIRAS1,SYT6,MFSD2A,ZDHHC22,DCLK1,ZMYND8,ACOT7,CAMKV,SEMA5B,PIK3CD,UBTF,FADS2,CRMP1,VCAN,RIMS4,IGSF1,ECE2,TOX,LRP8,PTPRZ1,RABGAP1L,KCNK1,NAV2,KCNQ2,NKAIN1,JMJD1C,EEF1A2,SFXN5,CACNG7,FGFBP3,LINC00599" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_500 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.13E-04 1.00E+00 1.83E-03 1.65E-02 15 147 "EPS8,ADORA1,BCAR3,SEMA6C,SH3GL2,CADPS,CSPG5,TNIK,GPM6B,PADI2,SERPINE2,MASP1,JAKMIP2,PLPPR4,DTNA" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.26E-04 1.00E+00 1.91E-03 1.71E-02 7 37 "FABP7,GRAMD1B,ACSBG1,FADS2,MICAL2,VCAN,PTCH1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.29E-04 1.00E+00 1.92E-03 1.72E-02 21 249 "ZNF365,ASPH,SON,DNER,CAMTA1,UNC5D,ADGRL3,TBX15,DDR2,GRIA2,PCDH8,DCLK1,NLGN3,PRRX1,TOX,MAGI2,KCNA4,PTPRE,TMEM255A,FAM13C,CBLN2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000_K2 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 3.29E-04 1.00E+00 1.92E-03 1.72E-02 18 197 "EPS8,ACTN2,ADCY2,MOBP,SLC1A2,SLC6A9,ARPP21,ADGRB2,C11orf87,C1QC,UNC5D,ADGRL3,REPS2,NXPH1,PLCH2,CADM2,PCDH15,DLG2" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_1000 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.37E-04 1.00E+00 1.96E-03 1.76E-02 15 148 "GRAMD1B,PPM1E,GPAM,ATP1A3,ALDH1L1,ACSBG1,TGFBR3,GUCY1A1,CD81,PCDH9,LGI1,FADS2,FAT3,ABCC9,SLC6A15" Computational M15730 MODULE_11 Genes in the cancer module 11. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.24E-27 8.63E-25 8.63E-25 6.15E-24 100 540 "SERPINA3,ABAT,MAPT,APC2,MBP,F3,RTN1,FABP7,CHST15,AGT,ACTL6B,FOXG1,AMPH,ANK3,APBA2,APBB1,NTNG1,TACC2,BCAS1,AQP4,SLC1A6,RPH3A,PDE8B,CSPG5,SLIT1,TAGLN3,ALDH4A1,SNAP25,SNCB,ATP2B2,GABBR1,KIF21B,SOX10,GAD2,KIF1B,NCAM1,LMO3,COLGALT2,GFAP,GJB1,RND1,MLC1,ABCC8,GNG4,MYRF,CACNA1A,GPM6A,ACSL6,NRGN,HAP1,GRIA2,GRIN1,OMG,NEURL1,PAX6,PCDH9,DCLK1,PDE2A,PDE4B,CHGA,PLEKHB1,CADM1,NRXN1,HPR,FADS2,SULT4A1,CABP1,COL9A2,CRMP1,TENM4,FEZ1,PLCH2,VCAN,NCAN,PRKACB,PRKCZ,ARHGEF4,MAPK10,KLK6,ZBTB16,PSD,RIMS3,PHYHIP,ELMO1,MAGI2,PTPRD,PARD6A,PTPRO,PTPRZ1,SV2A,KCNJ4,TMCC2,ARNT2,KCNK1,DPP6,L1CAM,RGS7,EEF1A2,ELAVL4,RCAN2" Computational M12065 MODULE_66 Genes in the cancer module 66. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.36E-24 1.64E-21 7.20E-22 5.13E-21 96 552 "SERPINA3,ABAT,ASIC1,MAPT,APC2,MBP,F3,RTN1,FABP7,CHST15,AGT,ACTL6B,FOXG1,AMPH,ANK3,APBA2,APBB1,TACC2,BCAS1,AQP4,SLC1A6,RPH3A,PDE8B,CSPG5,SLIT1,TAGLN3,ALDH4A1,SNAP25,SNCB,ATP2B2,GABBR1,KIF21B,SOX10,NCAM1,GFAP,GJB1,RND1,MLC1,ABCC8,GNG4,MYRF,CACNA1A,GPM6A,ACSL6,NRGN,GRIA2,GRIN1,TF,OMG,NEURL1,PAX6,PCDH9,DCLK1,PDE2A,PDE4B,CHGA,PLEKHB1,CADM1,NRXN1,HPR,FADS2,SULT4A1,CABP1,COL9A2,CRMP1,TENM4,FEZ1,PLCH2,VCAN,NCAN,PRKACB,PRKCZ,ARHGEF4,MAPK10,KLK6,ZBTB16,PSD,RIMS3,PHYHIP,ELMO1,MAGI2,PTPRD,PARD6A,PTPRO,PTPRZ1,SV2A,KCNJ4,TMCC2,ARNT2,KCNK1,DPP6,L1CAM,RGS7,EEF1A2,ELAVL4,RCAN2" Computational M19344 MODULE_100 Genes in the cancer module 100. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.10E-24 2.16E-21 7.20E-22 5.13E-21 95 544 "SERPINA3,ABAT,ASIC1,MAPT,APC2,MBP,F3,RTN1,FABP7,CHST15,AGT,ACTL6B,FOXG1,AMPH,ANK3,APBA2,APBB1,TACC2,BCAS1,AQP4,SLC1A6,RPH3A,PDE8B,CSPG5,SLIT1,TAGLN3,ALDH4A1,SNAP25,SNCB,ATP2B2,GABBR1,KIF21B,SOX10,NCAM1,GJB1,RND1,MLC1,ABCC8,GNG4,MYRF,CACNA1A,GPM6A,ACSL6,NRGN,GRIA2,GRIN1,TF,OMG,NEURL1,PAX6,PCDH9,DCLK1,PDE2A,PDE4B,CHGA,PLEKHB1,CADM1,NRXN1,HPR,FADS2,SULT4A1,CABP1,COL9A2,CRMP1,TENM4,FEZ1,PLCH2,VCAN,NCAN,PRKACB,PRKCZ,ARHGEF4,MAPK10,KLK6,ZBTB16,PSD,RIMS3,PHYHIP,ELMO1,MAGI2,PTPRD,PARD6A,PTPRO,PTPRZ1,SV2A,KCNJ4,TMCC2,ARNT2,KCNK1,DPP6,L1CAM,RGS7,EEF1A2,ELAVL4,RCAN2" Computational M2519 MODULE_137 CNS genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.66E-23 1.15E-20 2.88E-21 2.05E-20 94 546 "SERPINA3,ABAT,ASIC1,MAPT,APC2,MBP,F3,RTN1,FABP7,CHST15,AGT,ACTL6B,FOXG1,AMPH,ANK3,APBA2,APBB1,TACC2,BCAS1,AQP4,SLC1A6,RPH3A,ASCL1,CSPG5,SLIT1,TAGLN3,ALDH4A1,SNAP25,SNCB,ATP2B2,GABBR1,KIF21B,SOX10,NCAM1,GJB1,RND1,MLC1,ABCC8,GNG4,MYRF,CACNA1A,GPM6A,ACSL6,NRGN,GRIA2,GRIN1,TF,OMG,NEURL1,PAX6,PCDH9,DCLK1,PDE2A,PDE4B,CHGA,PLEKHB1,CADM1,NRXN1,HPR,FADS2,SULT4A1,CABP1,COL9A2,CRMP1,TENM4,FEZ1,PLCH2,VCAN,NCAN,PRKACB,PRKCZ,ARHGEF4,MAPK10,KLK6,ZBTB16,PSD,RIMS3,PHYHIP,ELMO1,MAGI2,PTPRD,PARD6A,PTPRO,SV2A,KCNJ4,TMCC2,ARNT2,KCNK1,DPP6,L1CAM,RGS7,EEF1A2,ELAVL4,RCAN2" Computational M10137 GNF2_RTN1 Neighborhood of RTN1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.29E-14 8.97E-12 1.79E-12 1.28E-11 22 52 "MAPT,RTN1,ANK2,CSPG5,ASTN1,SCN3B,MYT1L,NMNAT2,KIF1B,FXYD6,GPM6A,INA,DCLK1,NRXN1,NRXN2,NCAN,CTNND2,FAM131B,DNAJC6,STMN4,KCNQ2,RGS7" Computational M3373 GNF2_DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.04E-13 4.20E-10 7.00E-11 4.99E-10 24 73 "MAPT,AMPH,SH3GL2,ZNF365,RPH3A,TAGLN3,SNAP25,SNCB,ATP2B2,NMNAT2,NAP1L2,CAMTA1,GNG3,CAMK2A,PSD3,SULT4A1,CTNND2,PHYHIP,SV2A,ARNT2,KCNQ2,RGS7,EPB41L1,RCAN2" Computational M15252 GCM_MAPK10 Neighborhood of MAPK10 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.36E-12 9.48E-10 1.36E-10 9.65E-10 25 82 "MBP,IL17D,NDRG2,FGF1,ATP1A2,GABBR1,AHCYL1,NMNAT2,NFASC,LMO3,DDHD2,GPM6B,CAMK2A,CAMK2G,DCLK1,PLEKHB1,FEZ1,CTNND2,NRSN1,MAPK10,ANKS1B,DNAJC6,KCNJ10,ARNT2,DTNA" Computational M18929 MODULE_12 Spinal cord (neuro-development) genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.51E-12 1.75E-09 2.18E-10 1.56E-09 56 360 "SERPINA3,ABAT,MBP,F3,RTN1,FABP7,CHST15,AGT,FGF1,C1orf61,ANK3,APBA2,APBB1,BCAS1,AQP4,SNAP25,GABBR1,SOX10,NCAM1,LMO3,COLGALT2,GFAP,GJB1,MLC1,MYRF,GPM6A,ZEB1,GRIA2,GRIN1,OMG,INA,DAAM2,PAX6,TNFRSF1B,PCDH9,DCLK1,PDE4B,CADM1,TJP2,FADS2,CRMP1,FEZ1,VCAN,NCAN,ARHGEF4,KLK6,ZBTB16,KIAA0513,PTPRZ1,SV2A,ARNT2,DNM2,DPP6,L1CAM,EEF1A2,EPB41L2" Computational M8546 GNF2_MAPT Neighborhood of MAPT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.41E-10 1.67E-07 1.86E-08 1.33E-07 16 41 "MAPT,RTN1,ANK2,SH3GL2,SNCB,SCN3B,KIF1B,GPM6A,PSD3,GRIA2,NRXN1,SV2A,ARNT2,KCNQ2,RGS7,ELAVL4" Computational M3849 GNF2_AF1Q Neighborhood of AF1Q MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.67E-08 2.55E-05 2.55E-06 1.82E-05 11 25 "RTN1,ANK2,CSPG5,ASTN1,MYT1L,GPM6A,INA,DCLK1,NCAN,STMN4,PTPRD" Computational M16631 GCM_MAP1B Neighborhood of MAP1B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.25E-07 2.96E-04 2.69E-05 1.91E-04 16 65 "AMER2,CDC42BPA,PHYHIPL,KIF1B,NCAM1,CLASP2,BTRC,DIRAS1,CELF3,RBFOX2,DUSP26,SPIRE1,CEP170,PTPRD,RABGAP1L,ABI2" Computational M15601 GNF2_RAB3A Neighborhood of RAB3A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.74E-07 3.30E-04 2.75E-05 1.96E-04 12 37 "SH3GL2,TAGLN3,GABBR1,GRM3,SULT4A1,SV2A,ARNT2,KCNQ2,DPP6,RGS7,EPB41L1,RCAN2" Computational M4537 GCM_AQP4 Neighborhood of AQP4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.12E-07 4.96E-04 3.81E-05 2.72E-04 13 45 "TTYH1,IL17D,NDRG2,AGT,AQP4,PDE8B,AHCYL1,DNER,GPM6B,DAAM2,ARNT2,DTNA,EPB41L2" Computational M17046 GCM_PTK2 Neighborhood of PTK2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.75E-06 1.22E-03 8.68E-05 6.18E-04 24 145 "KIAA1109,PKP4,SESN3,SHTN1,CCDC88A,PHYHIPL,USP33,AHCYL1,KIF1B,CLASP2,DDHD2,BTRC,DIRAS1,CAMK2G,PLEKHB1,DZIP3,ANKS1B,SPIRE1,DNAJC6,OCIAD1,PTPRD,SNX27,RTN4,ABI2" Computational M10191 GCM_MAP4K4 Neighborhood of MAP4K4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.38E-06 2.35E-03 1.57E-04 1.12E-03 26 171 "APC2,IL17D,KIAA1109,SESN3,CCDC88A,TNIK,AHCYL1,KIF1B,CLASP2,ERBIN,DDHD2,BTRC,GPM6B,PLEKHB1,DZIP3,ANKS1B,SPIRE1,OCIAD1,PTPRD,ARNT2,SNX27,DTNA,RTN4,SH3GLB1,ABI2,EPB41L2" Computational M13367 GNF2_TM4SF2 Neighborhood of TM4SF2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.22E-06 5.03E-03 3.14E-04 2.24E-03 9 26 "HPCAL4,SH3GL2,TAGLN3,SNAP25,ATP2B2,NMNAT2,NAP1L2,PHYHIP,SV2A" Computational M2283 MODULE_41 Genes in the cancer module 41. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.43E-05 1.69E-02 9.96E-04 7.10E-03 56 566 "MAG,APC2,EMID1,ARID1A,NDRG2,ACTL6B,NTNG1,TACC2,SLC1A6,RPH3A,SLC6A9,TAGLN3,SNAP25,KIF21B,SOX10,GAD2,SPART,COLGALT2,MLC1,ABCC8,VAMP1,GNG4,CDK5R2,ADGRL3,GPR17,HAP1,GRIK2,TJP1,NEURL1,PAX6,REPS2,TNR,SEZ6L,LILRA4,MAGI1,NTSR2,ASIC3,TUB,PHKG1,SLC22A6,NRXN1,HPR,SULT4A1,VAV2,FAM131B,ECE2,PSD,PHYHIP,PTPRD,KCND3,KCNJ4,DNAH9,L1CAM,EFNA3,LMO1,RCAN2" MicroRNA hsa-miR-3175:mirSVR_lowEffct hsa-miR-3175:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-71 8.30E-68 8.30E-68 7.61E-67 148 1841 "DPF1,ABAT,ZFYVE27,ASIC1,CDHR1,RTN3,RCSD1,FAM43B,MRVI1,ATAT1,KCNIP2,GALNT13,FABP7,ERMN,GRAMD1B,HOGA1,SCN3A,SCN4B,LRRC7,ELMOD1,TRIM46,CNIH2,ITSN1,SLITRK3,BCAS1,SHTN1,PAAF1,MIER1,KIAA1614,SLC1A7,RUFY2,MSR1,MSRA,SLC8A2,SLC8A3,CCDC88A,DACH2,SPHKAP,SLIT1,TAGLN3,ASPH,ASTN1,RCOR3,C10orf105,B3GAT1,TMEM108,ATP1A3,EIF4G3,ATP2B2,GABBR1,SCN3B,WDTC1,MYT1L,JPH4,KIF1B,STARD10,ADGRB2,NPAS3,ALDH1L1,SMOC1,GPR162,GFAP,KIRREL3,PHLDB1,NEUROD1,NFIA,PCDH11X,NHLH1,SEMA4A,MYRF,CDK5R2,BTRC,GOLGB1,WWC1,KLHL4,TBX15,PRUNE2,DDR1,TCF7L2,CAMK2A,TMEM151B,NUMA1,AKNA,TF,DAAM2,TNFRSF1B,IGSF21,PADI2,C1orf94,SEZ6L,PCSK2,PRMT8,PLEKHB1,CASC2,HERC2P3,CCSER2,FADS2,FLRT1,PLXNB3,CELF5,BTF3L4,FAT3,MED1,CRMP1,PPP2R5C,MICAL2,ATRNL1,RIMS4,SDC3,KIAA1755,CMTM5,PRKCG,CTNND2,ECE2,MASP1,PLPPR5,SIRPA,PTAFR,PMEPA1,PRDM2,LRP8,CSDE1,KCNA6,PTPRE,KCNC1,PTPRO,SRGAP3,NAV2,PEX5,SNX27,DLG2,HS3ST4,RAB5B,KLRC2,SLC25A48,DNM2,FAM66C,DPP6,RALGDS,ZYG11B,ARHGEF10L,RNF220,SIDT2,CACNG7,EFNA3,SH3GLB1,VWA5A,EPB41L1" MicroRNA hsa-miR-324-3p:mirSVR_lowEffct hsa-miR-324-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-62 1.31E-58 6.53E-59 5.99E-58 140 1917 "MAG,TTYH1,MAP6,ASIC1,RBM10,RCSD1,MEG3,MRVI1,ATAT1,CSMD2,KCNIP2,NDRG2,ADCY2,FABP7,SORCS1,ADORA1,FCGR1A,SNX32,GOLGA7B,MOBP,SFPQ,PPM1E,DGKZ,GPAM,ZCCHC17,NLGN1,ST3GAL3,JAKMIP3,MADD,LRRC55,SLC6A9,TMEM249,GPR153,DLL3,KBTBD12,TMEM151A,CCDC181,PALLD,DKK3,USP33,WDTC1,KIF21B,CADM3,ZSWIM8,NMNAT2,ENKUR,JPH4,B4GALNT1,ARPP21,TTLL9,CPLX2,NCAM1,BCL2L2,ALDH1L1,SMOC1,GFAP,NCDN,INKA2,HEPN1,KIRREL3,RND1,AJAP1,VAMP1,PCDH11X,CAMTA1,WWC1,ANO4,TBX15,NEU4,CACNB2,NRGN,NUMA1,GRIA1,GRIN1,GPR88,CYB561A3,PTPN5,LEFTY2,FBXL16,TJP1,AIFM1,ZDHHC22,TNFRSF1B,PADI2,PTGDR2,LILRA4,PDE3B,IGFN1,PRMT8,PDE4B,FNDC5,BEST3,CHGA,ASIC3,PLEKHB1,TUB,DUSP26,NRXN1,UBTF,TJP2,ST8SIA5,NSD2,FAAP20,ATCAY,MFSD4A,POU3F2,CHD1L,MED1,SNCAIP,PPP3CB,FEZ1,MICAL2,PLCH2,SDC3,WBP1L,PHYHIP,TOMM20,PSMD13,COPS7A,CDH20,KCNA6,KCND3,KCNJ9,KCNJ10,KCNMA1,NKAIN1,RAB3IL1,RAB5B,PLEKHB2,RALGDS,SLC25A41,RAP1GAP,L1CAM,RFX5,PHC2,SFXN5,SIDT2,EFNA3,LRRC23,RASGRP2" MicroRNA hsa-miR-582-5p:mirSVR_highEffct hsa-miR-582-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.03E-61 3.27E-57 1.09E-57 9.99E-57 136 1847 "EPS8,RPL38,MAP6,SYT9,LGR4,RCSD1,ADGRV1,ARID1A,CSMD3,NDRG2,ADAR,ADD3,WAC,ERMN,GRAMD1B,LRRTM4,LRRC7,FGR,ELMOD1,FOXG1,SFPQ,SGIP1,ANK1,PPFIA1,ITSN1,APC,BCAS1,SHTN1,AQP4,ZNF365,MIER1,SLC1A6,SHANK2,SCG3,CAPRIN2,ASPH,SMARCE1,B3GAT1,SNAP25,ATM,EIF4G3,DKK3,MYT1L,B3GALT2,SOX5,KIF1B,GART,NPAS3,SPART,C11orf87,CLASP2,COLGALT2,ERBIN,ADHFE1,ABCC8,GLS,DDHD2,CAMSAP2,ADGRL3,GOLGB1,ANO4,CACNA1E,NPPA,CACNB2,TCF7L2,GPR17,TCF12,PTBP2,EML4,GRIA2,GRIA4,GRID1,GRIK2,CRB1,PTPN5,TLL2,CD81,LGI1,TPM4,MAGI1,BEST3,ADGRG1,HMGB1,CASC2,NEGR1,NMT2,CCSER2,P2RY12,POU3F2,ETNPPL,CHD1L,KCNT2,MICAL2,VCAN,RBPJ,PRKACB,DZIP3,PRKCZ,MAPK10,PUM1,MASP1,TOX,TOMM20,LRRTM3,ITGAV,BDNF-AS,PTHLH,PRDM2,RGMA,ZC3H11A,PLPPR4,KCNC1,PCDH15,KCNMA1,PEX5,TMEM255A,DPP6,RASGRF1,FAM13C,DTNA,RTN4,PAK5,ABCC9,JMJD1C,RGS7,ATL1,ZNF248,TTLL7,VANGL2,RLBP1,SSPN,FGFBP3,ARHGAP12,ELAVL3,TMEM100,EPB41L2" MicroRNA hsa-miR-642:mirSVR_lowEffct hsa-miR-642:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.78E-59 4.22E-55 1.05E-55 9.67E-55 138 1985 "TTYH1,PRR5L,ASIC1,MAPT,DUSP27,MEG3,ADGRV1,ATAT1,LDLRAD3,KCNIP2,HHATL,FABP7,PNMA8B,SORCS1,ERMN,AMER2,FOXRED2,NLGN4X,FGF1,PDZD4,SOX6,ASRGL1,ANK1,PPFIA1,ITSN1,ANXA7,SH3GL2,APBB1,MAGI3,GPAM,LRRC55,SLC14A1,DACH2,GPR153,SCG3,CAPRIN2,MTR,ASTN1,RCOR3,KBTBD12,SNCB,CCDC181,NRG3,ATP2B2,MEGF11,TNIK,AHCYL1,ENKUR,B4GALNT1,TTLL9,IDI2-AS1,KIF1B,FXYD6,NPAS3,NFASC,NCAM1,SMOC1,NCDN,HEPN1,GJB1,SEPT3,FAM168A,ARHGEF7,ABCC8,DDHD2,GNG3,TBX15,WSCD1,DDR1,PRLHR,PTBP2,CAMK2A,TMEM151B,GRIA2,GRID1,SPX,TMEM9,GUCY1A1,ZDHHC22,CDC42,DCLK1,MAGI1,ZNF384,PDE1C,PDE3B,PIRT,CIART,ZMYND8,ANO5,CASC2,SERPINE2,KIAA1549L,NRXN2,SEMA5B,CPT1C,FLRT1,BEST1,PRRX1,FAT3,MED1,ATRNL1,CHD5,NCAN,DZIP3,NOS1AP,MASP1,WBP1L,PHYHIP,TOMM20,PRTFDC1,ZC3H11A,CDH20,PTPRE,PLPPR4,PTPRO,KCNH1,SRGAP3,NTM,RABGAP1L,DLG2,DNAH9,RAB5B,PID1,PARP11,RAP1GAP,ATN1,RASGRF1,GNE,DTNA,PAK5,CAMK1G,RFX5,ARHGEF10L,VANGL2,SYT15,ABI2,ELAVL4,BAALC" MicroRNA hsa-miR-520f:mirSVR_lowEffct hsa-miR-520f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.87E-58 2.64E-54 5.27E-55 4.84E-54 131 1801 "ACER3,LGR4,DUSP27,LDLRAD3,MDM4,CSMD3,ADARB2,ADCY2,SORCS1,NLGN4X,GPR158,HOGA1,LRRC7,FGR,MOBP,MOG,PDZD4,SOX6,ERICH3,ANK3,PPFIA1,ITSN1,SESN3,GPAM,SLC1A6,LRRC55,SLC6A9,ARFGAP2,CCDC88A,DACH2,SCG3,SLCO1A2,CAPRIN2,MTR,SMARCE1,NRG3,EIF4G3,ATP2B2,DKK3,SON,SOX5,ENKUR,TTLL9,NPAS3,C11orf87,ALDH1L1,NDUFA5,NFIA,ARHGEF7,GLS,VAMP1,ZNF638,DCLK2,GNAS,DDHD2,MYRF,PRUNE2,GPM6A,CACNB2,NUDT21,DDR2,GRIA1,GRIA2,GRID1,GRIK2,OMG,OPCML,CRB1,MFSD2A,AIFM1,KCNK10,PAX6,HPS5,TNS1,PCDH8,DCLK1,PTGDR2,RBFOX2,ARHGAP19,PIRT,TUB,MS4A7,TMEFF2,BEST1,BTF3L4,SPATA6,IFFO1,FAT3,NXPH1,MFSD4A,CRLS1,PPP2R5C,SNCAIP,RGS6,OSBPL3,PRKACB,FMN2,PLD5,PRKCZ,USP54,NRSN1,MAPK10,BRINP3,ZBTB16,GON4L,SIRPA,CA10,JAKMIP2,PTHLH,CADM2,PTPRD,SRGAP3,CCDC3,KCNK2,DLG3,NKAIN1,WIPF2,SLC17A6,RAD52,ZYG11B,RFX4,JMJD1C,INSYN2,ATL1,ARHGEF10L,VANGL2,SH3GLB1,C2orf80,TMEM100,RCAN2,UEVLD" MicroRNA hsa-miR-383:mirSVR_lowEffct hsa-miR-383:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-57 1.31E-53 2.18E-54 2.00E-53 129 1766 "RABEPK,ACER3,MAPT,ACLY,MBP,SYT9,RTN3,RCSD1,FAM43B,ATAT1,ARID1A,CSMD3,ADAR,WAC,FABP7,SORCS1,TESK2,LRRTM4,PLA2G6,UNC79,SLC30A10,MOBP,PKP4,PPM1E,SESN3,SORBS1,BCAS1,SHTN1,SLC2A5,MSR1,LRRC55,CCDC88A,NSG2,SLCO1A2,SMARCE1,C10orf105,KBTBD12,TMEM108,ATM,PHYHIPL,SCN3B,MYT1L,ZSWIM8,B4GALNT1,ARPP21,KIF1B,DNER,NCAM1,NDUFA5,GPR162,NCDN,NELL1,KIRREL3,ADHFE1,AJAP1,NFIA,MLC1,ARHGEF7,PCDH11X,ZNF638,LUZP2,DCLK2,GPM6B,ACSL6,GPR17,TCF12,NRGN,RFFL,OMG,OPCML,TMEM9,AIFM1,CELF3,PAX6,CDC42,DCLK1,RBFOX2,PCSK2,MAGI1,PDE3B,PDE4B,CIART,FNDC5,DLGAP3,NEGR1,CCSER2,PRRX1,CNRIP1,MFSD4A,CHD1L,CRLS1,PPP3CB,OSBPL3,RBPJ,PRKACB,PRKCG,USP54,PUM1,NOS1AP,KIAA0408,ZBTB16,PLPPR5,LRRTM3,ELMO1,BLOC1S6,KCNA2,OCIAD1,PTPRE,PLPPR4,SV2A,NTM,CCDC3,PCDH15,DLG2,RAB5B,KLRC2,SLC25A48,PLEKHB2,FAM13C,NUP214,RGR,ZNF248,VANGL2,SEC61A2,FGFBP3,RPE65,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-107:mirSVR_lowEffct hsa-miR-107:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-56 1.24E-52 1.55E-53 1.42E-52 134 1955 "PRR5L,ACER3,MAP6,CDHR1,SYT9,RTN3,ADAR,SLITRK1,TMEM156,GPR158,LRRTM4,LRRC7,SEMA6A,SLC30A10,HPCAL4,SOX6,AMPH,APC,JAKMIP3,SHTN1,URGCP,MADD,MSR1,LRRC55,ARHGAP5,SLC8A2,CCDC88A,SLN,BRINP2,TMEM108,ATP2B2,MEGF11,SON,WDTC1,MYT1L,TNIK,CADM3,ADAM15,KIF1B,NFASC,ALDH1L1,NDUFA5,SMOC1,DCAF5,PHLDB1,NEUROD1,NFIA,GLS,VAMP1,ZNF638,NHLH1,SYT4,KAZN,CAMTA1,GNG4,CAMSAP2,MYRF,BTRC,TBX15,ATF7,VWC2,TCF7L2,EML4,PCDHGA3,SYT6,GRIA4,OMG,USP2,MFSD2A,TMEM9,NEURL1,ZFP91,PAH,PAX6,CDC42,PCDH9,ARHGAP19,TPD52,PDE4B,PIRT,PDYN,BEST3,ASIC3,MS4A7,HNRNPK,ARHGAP22,CAMKV,SEMA5B,DNAJC12,MEAF6,BEST1,IFFO1,NSD2,FAT3,POU3F2,SF1,CRLS1,PPP2R5C,PPP3CB,KCNT2,PRKAB2,DZIP3,RAB39A,NOS1AP,MASP1,WBP1L,RIMS3,DPYSL5,PTHLH,CADM2,ELMO1,PRDM2,COPS7A,PTPRE,SV2A,KCNMA1,NAV2,TMEM255A,FAM57B,C12orf4,ATN1,RASGRF1,BSDC1,ZYG11B,ATL1,ARHGEF10L,VANGL2,ABI2,VWA5A,SLC4A10,EN2,TMEM100,RCAN2,UEVLD" MicroRNA hsa-miR-103:mirSVR_lowEffct hsa-miR-103:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-56 1.24E-52 1.55E-53 1.42E-52 134 1955 "PRR5L,ACER3,MAP6,CDHR1,SYT9,RTN3,ADAR,SLITRK1,TMEM156,GPR158,LRRTM4,LRRC7,SEMA6A,SLC30A10,HPCAL4,SOX6,AMPH,APC,JAKMIP3,SHTN1,URGCP,MADD,MSR1,LRRC55,ARHGAP5,SLC8A2,CCDC88A,SLN,BRINP2,TMEM108,ATP2B2,MEGF11,SON,WDTC1,MYT1L,TNIK,CADM3,ADAM15,KIF1B,NFASC,ALDH1L1,NDUFA5,SMOC1,DCAF5,PHLDB1,NEUROD1,NFIA,GLS,VAMP1,ZNF638,NHLH1,SYT4,KAZN,CAMTA1,GNG4,CAMSAP2,MYRF,BTRC,TBX15,ATF7,VWC2,TCF7L2,EML4,PCDHGA3,SYT6,GRIA4,OMG,USP2,MFSD2A,TMEM9,NEURL1,ZFP91,PAH,PAX6,CDC42,PCDH9,ARHGAP19,TPD52,PDE4B,PIRT,PDYN,BEST3,ASIC3,MS4A7,HNRNPK,ARHGAP22,CAMKV,SEMA5B,DNAJC12,MEAF6,BEST1,IFFO1,NSD2,FAT3,POU3F2,SF1,CRLS1,PPP2R5C,PPP3CB,KCNT2,PRKAB2,DZIP3,RAB39A,NOS1AP,MASP1,WBP1L,RIMS3,DPYSL5,PTHLH,CADM2,ELMO1,PRDM2,COPS7A,PTPRE,SV2A,KCNMA1,NAV2,TMEM255A,FAM57B,C12orf4,ATN1,RASGRF1,BSDC1,ZYG11B,ATL1,ARHGEF10L,VANGL2,ABI2,VWA5A,SLC4A10,EN2,TMEM100,RCAN2,UEVLD" MicroRNA hsa-miR-342-3p:mirSVR_lowEffct hsa-miR-342-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.38E-56 3.46E-52 3.84E-53 3.52E-52 131 1879 "PRR5L,ACER3,MAPT,PAQR6,ADGRV1,ATAT1,CSMD2,ARID1A,KLHL32,ADCY2,WAC,FABP7,CHST15,LINC00461,LRRC7,ASIC4,BBOX1,GOLGA7B,FOXM1,TRIM46,SEMA6C,ANK2,CNIH2,ITSN1,DGKZ,NLGN1,SLC1A7,MADD,MSR1,MSRA,DACH2,CGREF1,SLCO1A2,DDX25,SCN3B,SON,CADM3,NMNAT2,SALL3,NEK6,TTLL9,KIF1B,ADGRB2,DNER,NASP,SPART,NFASC,LMO3,C11orf87,BCL2L2,STOX1,ADHFE1,SEPT3,MLC1,ZNF638,NHLH1,GNAS,CAMTA1,PRUNE2,ATF7,FAM69C,DDR1,TCF7L2,DIRAS1,AKNA,GRIA4,GRID1,ADAMTS8,GPR88,CRB1,MFSD2A,ZDHHC22,CDC42,PADI2,CDH8,CDH10,SEZ6L,LGI1,TPM3,PIRT,TMPRSS5,CHRM1,CASC2,MS4A7,HNRNPK,TMEFF2,HEPACAM,DUSP26,SERPINE2,CADM1,NEGR1,PIK3CD,UBTF,OPALIN,NSD2,TENM4,PPP3CB,FEZ2,OSBPL3,ATRNL1,NRSN1,PUM1,NOS1AP,MASP1,WBP1L,GON4L,PLPPR5,CADM2,ELMO1,PRDM2,RGMA,CSDE1,KCNA2,SMG7,KCNJ10,DLG3,CAB39L,DNAH9,SLC17A6,PLEKHB2,SUSD4,DTNA,PAK5,ABCC9,RFX4,JMJD1C,ARHGEF10L,ABI2,FGFBP3,SLC4A10,UEVLD" MicroRNA hsa-miR-532-3p:mirSVR_lowEffct hsa-miR-532-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.68E-56 4.16E-52 4.16E-53 3.82E-52 132 1913 "PRR5L,CDHR1,MBP,LGR4,MRVI1,RTKN,MDM4,KCNIP2,KLHL32,PNMA8B,ADORA1,TMEM156,ADORA3,FGF1,FGF14,ASIC4,MOBP,PDZD4,FOXM1,TRIM46,SEMA6C,ASRGL1,PPFIA1,ITSN1,ANXA7,GPAM,PAAF1,ZNF365,SLC1A6,SLC1A7,MADD,MSRA,PKNOX2,SLC6A9,YPEL4,MT3,NSG2,SLC14A1,CGREF1,SLCO1A2,C10orf105,ALDH4A1,GABBR1,WDTC1,AHCYL1,NMNAT2,ARPP21,TTLL9,SPART,NCAM1,STOX1,GFAP,HEPN1,POPDC3,GNAS,MYRF,TMEM136,FAM69C,DDR1,CACNB2,ZEB1,PTBP2,VXN,LINC00839,TMEM25,TMEM9,TLL2,ZDHHC22,ZFP91,HPS5,TNR,PADI2,CDH8,LGI1,MAGI1,ZNF384,PDE2A,PDYN,HMGB1,CHRM1,CASC2,HPCA,ZFYVE9,NRXN2,CAMKV,UBTF,CPT1C,NMT2,VAV2,PLXNB3,C11orf49,BEST1,NSD2,MFSD4A,MED1,RNF14,PTPA,SNCAIP,FEZ2,FEZ1,DOCK7,FMN2,CTNND2,NRSN1,ECE2,MASP1,RIMS3,GON4L,LRRTM3,BDNF-AS,CNIH3,COPS7A,OCIAD1,SRGAP3,KCNJ11,ARNT2,PEX5,HS3ST4,PID1,RAD52,PARP11,RALGDS,ATG16L1,RAP1GAP,DTNA,BSDC1,RFX4,ARHGEF10L,ZNF248,GPR61,TMEM100,PRRT4" MicroRNA hsa-miR-1913:mirSVR_lowEffct hsa-miR-1913:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-55 5.70E-52 5.18E-53 4.75E-52 126 1735 "MAG,TTYH1,MAP6,ASIC1,RBM10,MEG3,MRVI1,ATAT1,CSMD2,KCNIP2,NDRG2,ADCY2,FABP7,SORCS1,ERMN,ADORA1,SNX32,SEMA6A,MOBP,SFPQ,ITSN1,DGKZ,GPAM,NLGN1,ST3GAL3,JAKMIP3,MADD,SLC6A9,TMEM249,GPR153,DLL3,KBTBD12,TMEM151A,CCDC181,DKK3,USP33,WDTC1,KIF21B,CADM3,ZSWIM8,NMNAT2,ENKUR,B4GALNT1,TTLL9,CPLX2,FXYD6,NFASC,NCAM1,BCL2L2,ALDH1L1,GFAP,NCDN,RCOR2,KIRREL3,RND1,AJAP1,VAMP1,PCDH11X,ROBO3,CAMTA1,WWC1,ANO4,TBX15,NEU4,NUMA1,GRIA1,GRIN1,GPR88,PTPN5,LEFTY2,FBXL16,TJP1,ZDHHC22,TNFRSF1B,PTGDR2,LILRA4,PDE3B,IGFN1,PRMT8,PDE4B,FNDC5,BEST3,CHGA,ASIC3,PLEKHB1,TUB,UBTF,OPALIN,TJP2,ST8SIA5,C11orf49,ATCAY,MFSD4A,POU3F2,CHD1L,MED1,SNCAIP,PPP3CB,FEZ1,MICAL2,PLCH2,SDC3,USP54,ECE2,WBP1L,PHYHIP,TOMM20,PTAFR,COPS7A,CDH20,KCNA6,KCNJ10,KCNJ11,KCNMA1,NKAIN1,RAB5B,RALGDS,SLC25A41,RASGRF1,PHC2,RNF220,SFXN5,SIDT2,EFNA3,LRRC23,RASGRP2" MicroRNA hsa-miR-3184:mirSVR_lowEffct hsa-miR-3184:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-55 7.16E-52 5.96E-53 5.47E-52 131 1891 "DPF1,MAG,ACHE,EMID1,SYNDIG1,CEND1,ATAT1,LDLRAD3,CSMD2,WLS,KCNIP2,CLIP1,PLEKHG5,RYR1,ADD3,TOMM40L,SNX32,DISP3,PLA2G6,ASIC4,GOLGA7B,HPCAL4,MOG,AMPH,SGIP1,PI16,APBB1,NTNG1,SLITRK3,ST3GAL3,MIER1,RPH3A,BCO1,LRRC55,PKNOX2,SLC6A9,ARFGAP2,LGI3,NAXD,BRINP2,SORCS3,C10orf105,ADGRA1,ALDH4A1,TMEM151A,ATP2B2,GABBR1,SON,WDTC1,MYT1L,TNIK,CADM3,ZSWIM8,NMNAT2,JPH4,ADGRB2,ALDH1L1,GJB1,SEPT3,ROBO3,CDK5R2,CNTN2,GOLGB1,WWC1,TMEM136,DDR1,HAP1,AZIN2,TMEM151B,NUCB1,BRSK2,GRIA1,GRIK3,GRM3,TMEM25,TGFBR3,FBXL16,DAAM2,PADI2,PCDH8,HRH3,NTSR2,HPCA,GDAP1L1,KIAA1549L,NOMO2,OPALIN,CABP1,BEST1,IFFO1,ATCAY,MED1,PNKD,NKAIN4,MICAL2,NCAN,DZIP3,CMTM5,PRKCG,PLPP4,ARHGEF4,CTNND2,PUM1,NOS1AP,MASP1,WBP1L,PSMD13,SIRPA,PTCH1,BDNF-AS,RGMA,KCNA6,PARD6A,C1orf109,SV2A,RABGAP1L,KCNK2,DLG3,NKAIN1,WIPF2,DNAH9,DNM2,FAM57B,DTNA,CAMK1G,NUP214,JMJD1C,ARHGEF10L,SEC61A2,CACNG7,OLIG2" MicroRNA hsa-miR-218-5p:TargetScan hsa-miR-218-5p TargetScan 2.22E-55 1.20E-51 9.23E-53 8.47E-52 89 779 "DPF1,EPS8,ASIC1,LGR4,RTN3,MRVI1,CSMD3,GALNT13,LRRC7,PDZD4,CDC42BPA,ANK1,ITSN1,PKP4,GPAM,JAKMIP3,LRRC55,ARHGAP5,CCDC88A,PDE8B,GPR153,B3GAT1,DKK3,MYT1L,KIF21B,SALL3,LMO3,C11orf87,CLASP2,GFRA1,KIRREL3,AJAP1,NFIA,GNAS,GNG3,GNG4,ACSL6,DIRAS1,PSD3,GRIA2,RFFL,GRIK2,GRIK3,GRM3,GUCY1A2,REPS2,PCDH8,PCDH9,PDYN,HMGB1,NRXN1,NMT2,CNTN1,CELF5,FAT3,POU3F2,MED1,NCAN,RIMS4,RBPJ,DOCK7,PLD5,CTNND2,PUM1,PROX1,RIMS3,ANKS1B,JAKMIP2,CADM2,ELMO1,HP1BP3,MAGI2,KCNA1,KCNH1,RABGAP1L,KCNK2,KCNN3,DLG2,CAB39L,KIF2A,CALN1,RAD52,DPP6,RAP1GAP,RET,INSYN2,RNF220,ABI2,EPB41L1" MicroRNA hsa-miR-3161:mirSVR_lowEffct hsa-miR-3161:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.75E-55 2.03E-51 1.45E-52 1.33E-51 126 1755 "EPS8,ACER3,TMEM74,ACTN2,RTKN,ADCY2,KLRC4,GALNT13,FABP7,SLC44A5,CHST15,TOMM40L,TESK2,SCN4B,LINC00461,LRRC7,SEMA6A,HPCAL4,MOG,ANK2,USP28,PPFIA1,ANXA7,SH3GL2,PPM1E,APBA2,APC,ZCCHC17,BCAN,AQP4,SLC2A5,RUFY2,DACH2,CADPS,CAPRIN2,RCOR3,ATP1A3,ATP2B2,USP33,SON,MYT1L,TNIK,SALL3,IDI2-AS1,NPAS3,NCAM1,C11orf87,ERBIN,GFAP,NEUROD1,GLS,PCDH11X,DDHD2,UNC5D,TMEM136,CNDP1,KLHL4,TBX15,PRUNE2,GPM6B,ATF7,PTBP2,NUDT21,VSTM2A,GRIA2,GRIA4,GRIK2,LINC00839,TMEM9,TMEM257,PAH,CDH8,DCLK1,SEZ6L,PDE4B,PIRT,ZMYND8,CCSER2,OPALIN,TJP2,SLC25A27,PRRX1,SLC36A4,NSD2,NXPH1,ACBD5,MED1,SNCAIP,FEZ2,ATRNL1,PRKACB,DOCK7,FMN2,RAB39A,SYTL2,GON4L,TOMM20,PLPPR1,BDNF-AS,CADM2,PRDM2,CSDE1,MAGI2,KCNA1,KCNA4,OCIAD1,SMG7,PTPRZ1,NTM,WIPF2,RAD52,FAM13C,DTNA,PAK5,BSDC1,SLC6A15,ATL1,ZNF248,SYT15,SEC61A2,SLC39A12,SH3GLB1,FGFBP3,PRRT4,UEVLD,BAALC" MicroRNA hsa-miR-425:mirSVR_lowEffct hsa-miR-425:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.55E-55 5.17E-51 3.45E-52 3.16E-51 128 1831 "RABEPK,EPS8,SDE2,ABAT,RTN3,SYNDIG1,MRVI1,WLS,SLC25A25,ADD3,ERMN,TOMM40L,LRRTM4,LRRC7,TRIM46,USP28,PKP4,SESN3,NTNG1,DGKD,USP16,ZNF365,CADPS,SLCO1A2,LGI3,SORCS3,ALDH4A1,TMEM151A,PHYHIPL,DKK3,SCN3B,SON,MYT1L,GAD2,NMNAT2,ARPP21,IDI2-AS1,CPLX2,NAP1L2,NPAS3,SPART,NCAM1,C11orf87,ALDH1L1,GFAP,INKA2,ADHFE1,NEUROD1,SEPT3,LUZP2,DCLK2,UNC5D,GOLGB1,ANO4,ACSL6,TCF12,NUDT21,GRIA1,GRIA4,GRIK2,GPR88,OLR1,SHISA7,OPCML,LEFTY2,INA,P2RX7,AIFM1,PAX6,TNR,PCDH8,PCDH9,TPM3,ZNF384,PDE1A,BEST3,CASC2,GDAP1L1,ZFYVE9,KIAA1549L,ANLN,NMT2,SLC25A27,ETNPPL,SF1,RNF14,SNCAIP,PPP3CB,ATRNL1,RBPJ,PRKACB,DOCK7,KIAA1755,CTNND1,CTNND2,NRSN1,PUM1,TOX,SPIRE1,PLPPR5,LRRTM3,PLPPR1,PTHLH,OLFM3,PTPRZ1,SRGAP3,KCNJ10,KCNJ11,KCNMA1,DLG2,CAB39L,HS3ST4,WIPF2,KLRC2,KLRC3,FAM66C,DPP6,C12orf4,GOPC,DTNA,ABCC9,JMJD1C,RGS7,SIDT2,SH3GLB1,RAVER2,C2orf80,SEZ6" MicroRNA hsa-miR-505:mirSVR_lowEffct hsa-miR-505:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.84E-54 3.16E-50 1.98E-51 1.81E-50 123 1708 "RABEPK,SDE2,PRR5L,MBP,CNTNAP3,EYA1,ATAT1,LDLRAD3,KCNIP2,F3,ADCY2,ADD3,WAC,SNX30,TESK2,SCNN1D,KIAA1109,LRRC7,ELMOD1,MOBP,SOX6,ERICH3,ANK3,ANXA7,NTNG1,MAGI3,TACC2,SORBS1,JAKMIP3,AQP4,ZNF365,SLC7A14,SLC1A7,CCDC88A,NSG2,NAXD,DDX25,RCOR3,TMEM108,NRG3,SOX5,ZCCHC24,ZSWIM8,ARPP21,NPAS3,RAP1GAP2,NFASC,C11orf87,INKA2,NELL1,SLCO1C1,ARHGEF7,KAZN,GNAS,NODAL,BTRC,ADGRL3,GOLGB1,PRUNE2,ATF7,TCF7L2,ZEB1,HAP1,PTBP2,NUDT21,VSTM2A,GPR88,TMEM25,P2RX7,TMEM257,DAAM2,CDC42,PCDH8,CDH8,RBFOX2,LGI1,TPD52,PDE4B,TUB,NLGN3,GDAP1L1,NRXN1,NMT2,CCSER2,PMP2,NXPH1,MICAL2,ATRNL1,RBPJ,FMN2,HES5,ECE2,KIAA0408,WBP1L,ANKS1B,SYNC,PLPPR1,JAKMIP2,PMEPA1,PTHLH,CADM2,CEP170,KCNA1,KCNA2,PTPRE,KCNJ9,PEX5,DLG2,HS3ST4,PLEKHB2,PARP11,PAK5,JMJD1C,ZNF248,SYT15,SEC61A2,SH3GLB1,RPRD1A,VWA5A,ARHGAP12,ELAVL4,C2orf80,OLIG2" MicroRNA hsa-miR-330-3p:mirSVR_highEffct hsa-miR-330-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-53 5.76E-50 3.39E-51 3.11E-50 128 1871 "RABEPK,EPS8,LGR4,LDLRAD3,KCNIP2,KLHL32,RXRG,GALNT13,ADD3,SLC44A5,SCN3A,LRRTM4,LINC00461,FHL1,SLC30A10,FOXG1,AMPH,CCDC80,GPAM,CACHD1,SYBU,API5,USP16,ZNF365,SLC1A6,MADD,RUFY2,MSRA,ARFGAP2,CCDC88A,CADPS,SCG3,ASPH,TMEM108,NRG3,ATP2B2,USP33,SON,MYBPC1,ENKUR,KIF1B,SPART,ERBIN,NELL1,KIRREL3,SLCO1C1,LUZP2,MYRF,UNC5D,TBX15,GPM6A,LILRA1,TCF7L2,PTBP2,VXN,VSTM2A,GRID1,LINC00839,TGFBR3,USP2,INA,GUCY1A2,TJP1,ZFP91,PAH,TNR,PCDH9,MAGI1,PDE1A,CIART,ZMYND8,HPSE2,HNRNPK,JAM2,TJP2,MEAF6,BTF3L4,PRRX1,ACBD5,CNRIP1,POU3F2,CRLS1,PPP2R5C,PPP3CB,KCNT2,OSBPL3,RBPJ,PRKACB,PRKCZ,USP54,NRSN1,MAPK10,ZBTB16,TOX,ANKS1B,PSMD13,ELMO1,PRTFDC1,HP1BP3,LRP8,CEP170,BLOC1S6,KCNA4,OCIAD1,SMG7,C1orf109,RABGAP1L,KCNK2,PCDH15,PEX5,KIF2A,KLRC2,SLC17A6,PLEKHB2,DPP6,FAM13C,RFX4,RGS10,INSYN2,EFNA3,RBM12,RPRD1A,ARHGAP12,RAVER2,SLC4A10,EPB41L1,EPB41L2,RCAN2" MicroRNA hsa-miR-198:mirSVR_lowEffct hsa-miR-198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-53 8.99E-50 4.99E-51 4.58E-50 124 1755 "RIMKLA,LGR4,DUSP27,MEG3,MRVI1,ATAT1,LDLRAD3,CSMD3,RTN1,AMER2,CHST15,TOMM40L,KIAA1109,DISP3,LRRC7,HPCAL4,MOBP,SOX6,TRIM46,PPM1E,APBA2,NLGN1,API5,PAAF1,SFMBT2,PKNOX2,RTP5,NAXD,ASPH,ASTN1,TMEM108,ADGRA1,ATM,ATP2B2,SCN3B,SON,WDTC1,SOX5,ILDR2,ARPP21,NCAM1,COLGALT2,PHLDB1,PCDH11X,C1QC,OS9,KAZN,ROBO3,GNG4,CAMSAP2,MYRF,BTRC,CNDP1,KLHL4,TBX15,WSCD1,CACNA1E,LILRA1,TCF7L2,CAMK2G,BRSK2,GRIA4,OLR1,OMG,MFSD2A,TLL2,DAAM2,CDH8,SEZ6L,PDE3B,FNDC5,GPR37L1,PFKFB3,CASC2,HNRNPK,TMEFF2,TLX1,NLGN3,SULT4A1,VAV2,CELF5,COL9A2,NSD2,SF1,PPP3CB,NCAN,PRKAB2,DOCK7,CMTM5,PRKCG,PRKCZ,ARHGEF4,CTNND1,PSD,TOMM20,PTCH1,BDNF-AS,CADM2,ELMO1,DKFZp779M0652,COPS7A,CEP170,SRGAP3,DLG2,DLG3,KIF2A,TMEM255A,SLC17A6,RAD52,FAM66C,DPP6,RALGDS,ATG16L1,RAP1GAP,SUSD4,ZYG11B,RFX4,TTLL7,SEC61A2,RNF220,PIANP,ABI2,RAVER2,EPB41L2" MicroRNA hsa-miR-150:mirSVR_lowEffct hsa-miR-150:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-53 1.66E-49 8.72E-51 8.00E-50 130 1952 "TTYH1,ASIC1,RCSD1,MEG3,CLIP1,KLHL32,GRAMD1B,TOMM40L,HOGA1,TESK2,FGF14,TRIM46,ITSN1,PPM1E,APBA2,APBB1,NTNG1,GPAM,ZCCHC17,SORBS1,ARHGAP5,SLC8A3,SLC14A1,ASCL1,CAPRIN2,SORCS3,TNIK,SOX5,ZCCHC24,ZSWIM8,MYH7,ENKUR,ARPP21,TTLL9,ADAM15,KIF1B,CPLX2,NFASC,INKA2,HEPN1,PHLDB1,NEUROD1,AJAP1,ARHGEF7,ZNF638,POPDC3,LUZP2,NKX2-2,KAZN,UNC5D,TBX15,CAMK2G,VXN,AKNA,GRIA2,GRIA4,RFFL,ATP13A2,P2RX7,TMEM9,CELF3,ZDHHC22,MAEL,HPS5,MAGI1,PIRT,ZMYND8,FNDC5,TMPRSS5,PFKFB3,CASC2,MS4A7,HERC2P3,ZBED5,DUSP26,NLGN3,ZFYVE9,SEMA5B,NMT2,VAV2,NSD2,NXPH1,MFSD4A,POU3F2,CHD1L,PTPA,SNCAIP,RGS6,KCNT2,FEZ1,OSBPL3,CHD5,PKN2,PLD5,USP54,NRSN1,KIAA0513,RIMS3,PTCH1,ITGAV,ITIH2,PRDM2,BLOC1S6,OLFM3,OCIAD1,SV2A,SRGAP3,KCNJ10,KCNJ11,ARNT2,PCDH15,NAV2,KCNN3,PYGM,WIPF2,FAM66C,PARP11,RALGDS,SLC25A18,DSCAM,FAM13C,FAM135B,ARHGEF10L,ZNF248,RPRD1A,GPR61,SLC4A10,RPE65,LRRC23,SEZ6" MicroRNA hsa-miR-939:mirSVR_lowEffct hsa-miR-939:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.11E-53 3.31E-49 1.65E-50 1.52E-49 117 1566 "DPF1,TTYH1,SDE2,PRR5L,ZFYVE27,MAP6,CDHR1,EMID1,CSMD2,NDRG2,RXRG,GALNT13,ADCYAP1R1,GRAMD1B,TUBB4A,FCGR1A,FCGR1B,LRRTM4,GOLGA7B,MOBP,SOX6,SELL,CNIH2,NTNG1,DGKZ,BCAS1,API5,PAAF1,MIER1,PKNOX2,SLC8A2,LGI3,ARFGAP1,ASPH,BRINP2,ASTN1,SMARCE1,TMEM108,ATM,EIF4G3,GABBR1,SON,WDTC1,KIF21B,CADM3,ZSWIM8,CPLX2,FXYD6,C11orf87,ALDH1L1,GFAP,KIRREL3,RHBDL3,POPDC3,DCLK2,GNG3,GOLGB1,CACNA1E,PRLHR,TCF7L2,ZEB1,CAMK2A,PCDHGA3,TMEM151B,GRIK3,ATP13A2,PTPN5,TIE1,CELF3,DCLK1,ZNF384,PFKFB3,HEPACAM,GDAP1L1,NRXN2,CAMKV,UBTF,FTO,BTF3L4,MED1,SF1,NKAIN4,MICAL2,OSBPL3,ATRNL1,VCAN,RIMS4,ARHGEF4,NRSN1,EDRF1,ZNF385B,PTHLH,PRDM2,LRP8,COPS7A,CEP170,MAGI2,KCNA4,PTPRE,CCDC3,ARNT2,SNX27,CAB39L,RAB5B,DNM2,FAM66C,FAM57B,BSDC1,RFX4,RFX5,FAM135B,PHC2,RNF220,CACNG7,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-493*:mirSVR_highEffct hsa-miR-493*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-52 5.68E-49 2.71E-50 2.48E-49 128 1910 "ABAT,MAP6,EYA1,ARID1A,WLS,CSMD3,F3,CLIP1,GALNT13,GRAMD1B,FCGR1A,MOBP,ANK2,RASA3,PPFIA1,ANXA7,DOCK10,MAGI3,TACC2,CACHD1,NLGN1,ST3GAL3,API5,SHTN1,CLSTN1,USP16,MIER1,MADD,MSR1,LRRC55,YPEL4,CCDC88A,DACH2,CADPS,SORCS3,SMARCE1,MEGF11,SOX1,MYT1L,KIF21B,EMC1,SALL3,NEK6,KIF1B,GART,CPLX2,NAP1L2,NPAS3,RAP1GAP2,LMO3,ERBIN,SEPT3,ARHGEF7,PCDH11X,SYT4,CAMTA1,CAMSAP2,ADGRL3,CNDP1,ANO4,PRUNE2,GPM6A,GPM6B,CACNB2,TCF7L2,ZEB1,PTBP2,VSTM2A,GRIA4,TMEM25,LEFTY2,USP2,TLL2,PCDH9,CDH10,TPM3,ZNF384,ZMYND8,NLGN3,NRXN1,CAMKV,OPALIN,DNAJC12,SPATA6,SLC36A4,NXPH1,MFSD4A,MED1,PPP2R5C,PPP3CB,PRKCZ,IGSF1,CTNND2,KIAA0408,KLK6,TOX,PLPPR5,ZNF385B,LRRTM3,PTCH1,ITGAV,BDNF-AS,HP1BP3,CEP170,PTPRD,AK5,KCNJ10,KCNK1,KCNMA1,NAV2,DLG2,DNM2,C12orf4,SLC25A41,ABI1,FAM13C,L1CAM,RFX4,JMJD1C,RGS10,INSYN2,ATL1,ZNF248,EFNA3,RBM12,ARHGAP12,RPE65,BAALC" MicroRNA hsa-miR-616:mirSVR_lowEffct hsa-miR-616:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-52 7.52E-49 3.42E-50 3.14E-49 123 1759 "ABAT,PRR5L,ACER3,MAP6,CNTNAP3,MEG3,ADGRV1,ATAT1,KLHL32,GALNT13,SORCS1,ERMN,FCGR1A,KIAA1109,FGF14,SEMA6A,FGR,FHL1,SLC30A10,MOBP,SGIP1,ANK1,ANK3,ANXA7,SH3GL2,GPAM,NLGN1,LRRC4C,SLC7A14,MSR1,SLC8A3,CCDC88A,DACH2,PDE8B,SLCO1A2,CAPRIN2,ASPH,RCOR3,ATM,ATP1A2,PHYHIPL,MYT1L,SOX5,CPLX2,NPAS3,C11orf87,GPR162,ERBIN,SLCO1C1,NFIA,GLS,PCDH11X,ADGRL3,ANO4,ACSL6,PRLHR,PTBP2,NUDT21,CAMK2G,GRID1,MFSD2A,ZFP91,PAX6,CDC42,PCDH8,PTGDR2,PCSK2,PDE1C,PIRT,TMEFF2,KIAA1549L,DNAJC12,SLC25A27,COL9A2,SPATA6,SLC36A4,FAT3,CP,CRLS1,TENM4,FEZ2,OSBPL3,ATRNL1,VCAN,PHACTR3,PRKACB,DOCK7,DZIP3,SDC3,FMN2,PRKCZ,SLC45A1,IGSF1,PUM1,KIAA0408,WBP1L,ANKS1B,TOMM20,PSMD13,DNAJC6,CA10,JAKMIP2,PTHLH,STMN4,KCNC1,PTPRZ1,AK5,RABGAP1L,KCNK2,PCDH15,KLRC3,RALGDS,SUSD4,ATN1,PAK5,ABCC9,ZYG11B,RET,ABI2,VWA5A,ARHGAP12,SLC4A10,SEZ6" MicroRNA hsa-miR-587:mirSVR_highEffct hsa-miR-587:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-52 1.09E-48 4.76E-50 4.36E-49 124 1796 "RABEPK,ACER3,ACLY,SYT9,RTN3,SYNDIG1,SLITRK1,GALNT13,ADD3,SORCS1,SLC44A5,TOMM40L,TESK2,LRRC7,FGF14,ERICH3,ANK2,PPFIA1,ITSN1,PKP4,GPAM,NLGN1,API5,SLC1A6,RUFY2,MSR1,CCDC88A,SLC14A1,DACH2,CADPS,NAXD,CAPRIN2,ASPH,SORCS3,SMARCE1,CCDC181,PALLD,USP33,SON,WDTC1,MYT1L,NMNAT2,KIF1B,LMO3,CLASP2,COLGALT2,ERBIN,RGL1,AJAP1,PCDH11X,ZNF638,NHLH1,NKX2-2,GNAS,DDHD2,CAMTA1,ADGRL3,TMEM136,GPM6A,ACSL6,CACNB2,PTBP2,VXN,NUMA1,BRSK2,GRIA2,GRIA4,RFFL,GRIK2,GPR88,GRM3,AIFM1,HPS5,CDC42,PCDH9,CDH10,MAGI1,MS4A7,HNRNPK,TMEFF2,HEPACAM,CADM1,NRXN1,MEAF6,PMS2,P2RY12,NSD2,NXPH1,CP,MED1,RNF14,CRLS1,PPP2R5C,MICAL2,ATRNL1,DOCK7,FMN2,SLC45A1,CTNND1,CTNND2,TOX,SYTL2,ZNF385B,PTCH1,PTHLH,ZC3H11A,OLFM3,SMG7,NTM,AK5,PCDH15,CAB39L,RAB5B,KLRC2,PARP11,GOPC,FAM13C,DTNA,SLC6A15,RET,JMJD1C,FGFBP3,SLC4A10,EN2" MicroRNA hsa-miR-101:mirSVR_lowEffct hsa-miR-101:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.38E-52 1.29E-48 5.36E-50 4.92E-49 129 1956 "RABEPK,EPS8,PRR5L,ACER3,ASIC1,CNTNAP3,RCSD1,MEG3,ADGRV1,ATAT1,WLS,CSMD3,CLIP1,KLRC4,TOMM40L,FHL1,ELMOD1,AMPH,SFPQ,ITSN1,APBB1,APC,NTNG1,MAGI3,CCDC80,GPAM,ZCCHC17,TACC2,JAKMIP3,LRRC4C,PAAF1,CLSTN1,SHANK2,SMARCE1,RCOR3,ATM,EIF4G3,PHYHIPL,ATP2B2,DKK3,SCN3B,SOX1,CAB39,SALL3,KIF1B,GART,NPAS3,C11orf87,CLASP2,GFAP,RND1,NFIA,DDHD2,ANO4,PRUNE2,GPR19,PTBP2,NUDT21,CAMK2G,VXN,GRIA2,GRIK3,GRM3,OMG,CRB1,USP2,TJP1,SEZ6L,TPD52,PLEKHB1,CASC2,DLGAP3,KIAA1549L,FTO,CELF5,SLC25A27,PRRX1,P2RY12,ACBD5,MFSD4A,POU3F2,CRLS1,PTPA,MICAL2,ATRNL1,NCAN,RBPJ,DOCK7,FMN2,RAB39A,PKN2,USP54,PUM1,EDRF1,KIAA0408,TOX,PLPPR5,TUBB2B,LRRTM3,PTAFR,PTCH1,DNAJC6,CA10,BDNF-AS,CEP170,OLFM3,KCNA4,KCNA6,PTPRO,KCNK2,PCDH15,DLG3,KIF2A,ABI1,FAM13C,RTN4,PAK5,BSDC1,SLC6A15,RET,INSYN2,SYT15,SSPN,FGFBP3,ARHGAP12,SLC4A10,C2orf80,EPB41L1,EPB41L2" MicroRNA hsa-miR-548b-3p:mirSVR_lowEffct hsa-miR-548b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.52E-52 1.36E-48 5.45E-50 5.00E-49 129 1957 "EPS8,DUSP27,RCSD1,ADGRV1,MRVI1,CSMD2,PNMA8B,ADORA3,FCGR1A,TESK2,KIAA1109,UNC79,MOG,FOXM1,CDC42BPA,RASA3,PI16,PPFIA1,ITSN1,NLGN1,API5,MIER1,ARFGAP2,SLC8A3,DACH2,PDE8B,SLCO1A2,KBTBD12,SNAP25,CCDC181,ATP1A2,NRG3,DKK3,NMNAT2,ADAM15,DNER,NASP,LMO3,SMOC1,SLCO1C1,GLS,PCDH11X,KAZN,GNG3,GOLGB1,TMEM136,ANO4,WSCD1,GPM6A,TCF12,CAMK2A,NUMA1,GRIA2,GRIK2,GPR88,SPX,USP2,P2RX7,TIE1,TJP1,AIFM1,TLL2,ATG4C,DAAM2,MAEL,CDC42,IGSF21,PCDH9,TPD52,TPM3,ZNF384,PDE1C,ZMYND8,CHGA,CASC2,TUB,MS4A7,NLGN3,ANLN,UBTF,TJP2,FADS2,ST8SIA5,MEAF6,SLC25A27,NSD2,MFSD4A,POU3F2,MED1,CRMP1,SNCAIP,PPP3CB,ATRNL1,PHACTR3,PRKACB,DZIP3,USP54,CTNND2,NRSN1,MAPK10,PUM1,SYTL2,GON4L,CADM2,PRDM2,CSDE1,OCIAD1,RABGAP1L,PCDH15,NAV2,RAB5B,FAM57B,ATG16L1,ABI1,DSCAM,DTNA,ZYG11B,RFX5,FAM135B,INSYN2,ZNF248,VANGL2,PIANP,RPRD1A,FGFBP3,ELAVL3,ELAVL4,EN2,EPB41L1" MicroRNA hsa-miR-1197:mirSVR_lowEffct hsa-miR-1197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.86E-52 2.09E-48 8.05E-50 7.38E-49 125 1838 "TTYH1,PRR5L,ZFYVE27,MAP6,TMEM74,MBP,SYNDIG1,EXTL1,LDLRAD3,CSMD2,WLS,MDM4,SLC25A25,CSMD3,NDRG2,SORCS1,BCAR3,FOXG1,NTNG1,GPAM,DGKD,SLITRK3,ST3GAL3,LRRC4C,PAAF1,MIER1,SLCO1A2,NAXD,ASPH,SMARCE1,C10orf105,ALDH4A1,DKK3,NMNAT2,ENKUR,JPH4,ARPP21,LHFPL4,ADAM15,RAP1GAP2,NFASC,C11orf87,CLASP2,NDUFA5,GFAP,RCOR2,FAM168A,PCDH11X,DCLK2,GNAS,UNC5D,CNTN2,CACNA1A,FAM69C,TCF12,PTBP2,CAMK2G,VSTM2A,NUCB1,GRIA2,RFFL,GRIK3,CYB561A3,OPCML,TMEM25,LEFTY2,FBXL16,TMEM257,PAX6,REPS2,PCDH9,RBFOX2,LGI1,MAGI1,ZNF384,HMGB1,PFKFB3,CHRM1,HERC2P3,JAM2,HEPACAM,NLGN3,CADM1,KIAA1549L,CAMKV,NEGR1,PIK3CD,OPALIN,FTO,CNTN1,PMP2,PRRX1,SPATA6,NSD2,MFSD4A,CHD1L,CRLS1,PPP2R5C,OSBPL3,CHD5,PLPP4,CTNND1,MAPK10,MASP1,CSDE1,KCNJ10,TMCC2,ARNT2,CAB39L,SLC17A6,DPP6,RASGRF1,FAM13C,DTNA,BSDC1,ABCC9,SLC6A15,CRTAC1,VANGL2,RNF220,SLC39A12,RBM12,ARHGAP12,RCAN2,BAALC" MicroRNA hsa-miR-448:mirSVR_lowEffct hsa-miR-448:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-51 7.16E-48 2.65E-49 2.43E-48 125 1859 "ABAT,ACER3,CNTNAP3,SYT9,RTN3,ARID1A,RTKN,MDM4,CSMD3,NDRG2,CLIP1,GALNT13,TMEM156,SLC44A5,LRRC7,ASIC4,BCAR3,SOX6,TRIM46,AMPH,SFPQ,ANK1,ANK2,ANXA7,APC,NTNG1,SLITRK3,TACC2,BCAS1,SHTN1,SLC7A14,MSR1,LRRC55,ARHGAP5,SLC8A3,MT3,CGREF1,TAGLN3,B3GAT1,TMEM108,FYN,MEGF11,DKK3,USP33,SON,MYT1L,KIF1B,SPART,ALDH1L1,SMOC1,ERBIN,ADHFE1,NEUROD1,NFIA,ARHGEF7,GLS,ZNF638,GNG4,CAMSAP2,ADGRL3,VWC2,PRLHR,ZEB1,AZIN2,NUDT21,EML4,PCDHGA3,VSTM2A,GRIA1,GRIA4,GRIK3,ADAMTS8,OMG,REPS2,DCLK1,TPD52,MAGI1,CIART,PDYN,PFKFB3,HNRNPK,OPALIN,DNAJC12,CNTN1,PMP2,SLC25A27,BTF3L4,FAT3,PPP3CB,RGS6,FMN2,RAB39A,PRKCZ,KIAA0408,FGFR1OP2,TOMM20,SYNC,PTCH1,ITGAV,PLPPR1,JAKMIP2,PTHLH,HP1BP3,CEP170,MAGI2,KCNA1,PLPPR4,KCND3,AK5,KCNJ9,KCNK2,NAV2,DLG2,DLG3,FAM66C,PARP11,SUSD4,GOPC,RTN4,RFX5,FAM135B,ATL1,RERGL,RAVER2,YY1AP1" MicroRNA hsa-miR-3190-3p:mirSVR_lowEffct hsa-miR-3190-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-51 9.98E-48 3.57E-49 3.27E-48 123 1802 "EPS8,MAP6,DUSP27,MRVI1,ATAT1,LDLRAD3,SLC25A25,F3,DSCAML1,SLITRK1,GALNT13,TUBB4A,TOMM40L,TESK2,DISP3,FHL1,ELMOD1,FOXM1,SELL,ERICH3,ANK1,PPFIA1,ANXA7,APBB1,NTNG1,DGKZ,SHTN1,RPH3A,RUFY2,MSR1,PKNOX2,DACH2,SPHKAP,B3GAT1,ALDH4A1,ATP1A2,NRG3,SON,WDTC1,CAB39,ZSWIM8,NMNAT2,B4GALNT1,FXYD6,NFASC,LMO3,COLGALT2,NDUFA5,STOX1,GPR162,DCAF5,RCOR2,DCLK2,CAMTA1,ADGRL3,WWC1,CNDP1,WSCD1,CACNA1E,LRIT2,ZEB1,AZIN2,PTBP2,NUDT21,EML4,NUCB1,NUMA1,GRM3,OLR1,SHISA7,CRB1,TMEM9,CELF3,NEURL1,ZDHHC22,DAAM2,TNR,PADI2,TNS1,PCDH9,TPM4,PDE2A,DLGAP3,CAMKV,UBTF,CPT1C,SULT4A1,CNTN1,MFSD4A,PRKACB,FMN2,CTNND1,ECE2,MASP1,SYNC,PRDM2,COPS7A,KCNA6,PTPRE,PTPRZ1,SV2A,SRGAP3,AK5,KCNJ10,TMCC2,PCDH15,SNX27,OLIG1,SLC17A6,PARP11,RALGDS,SLC25A18,DTNA,RET,TTLL7,RNF220,PIANP,SH3GLB1,GPR61,VWA5A,ELAVL3,EPB41L1,RASGRP2" MicroRNA hsa-miR-3120:mirSVR_highEffct hsa-miR-3120:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-51 1.63E-47 5.62E-49 5.15E-48 128 1969 "EPS8,LOC100128239,MAPT,TMEM74,CNTNAP3,LGR4,ARID1A,AMER2,SLC44A5,CHST15,TESK2,AGT,SCN3A,KIAA1109,FHL1,SLC30A10,SELL,ERICH3,CDC42BPA,ANK1,ANK2,ANK3,PPFIA1,DOCK10,APC,MAGI3,GPAM,SORBS1,NLGN1,API5,SHTN1,RUFY2,MSR1,CCDC88A,PDE8B,CSPG5,SMARCE1,TMEM108,PALLD,SON,MYT1L,CAB39,KIF1B,GART,C11orf87,SMOC1,ERBIN,GJB1,SEPT3,ARHGEF7,DDHD2,CAMSAP2,MYRF,ADGRL3,GOLGB1,ANO4,CACNB2,TCF7L2,B4GALNT4,GRIA1,GRIA2,GRIA4,GRIK2,VWCE,LINC00839,LEFTY2,MFSD2A,INA,CDC42,PCDH9,PTGDR2,MAGI1,PDE1C,PDE3B,PDE4B,HMGB1,CA14,HNRNPK,SERPINE2,CADM1,NOMO2,TJP2,BTF3L4,PRRX1,P2RY12,NXPH1,PTPA,PPP3CB,MICAL2,ATRNL1,PRKACB,PLPP4,PKN2,PRKCZ,CTNND2,EDRF1,TOX,SPIRE1,TOMM20,ZNF385B,DNAJC6,ITGAV,CA10,PRDM2,ZC3H11A,OLFM3,OCIAD1,PTPRD,SMG7,C1orf109,SRGAP3,KCNK1,KCNK2,PCDH15,PEX5,KLRC2,TMEM255A,DNM2,SLC17A6,DPP6,RASGRF1,DTNA,FAM135B,ZNF248,SEC61A2,RBM12,ABI2,VWA5A" MicroRNA hsa-miR-491-5p:mirSVR_lowEffct hsa-miR-491-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.22E-51 4.99E-47 1.62E-48 1.49E-47 124 1861 "SERPINA3,ACER3,ACHE,CDHR1,SYT9,PAQR6,EXTL1,CEND1,FAM43B,MRVI1,CSMD2,KCNIP2,SLC25A25,PLEKHG5,RXRG,GRAMD1B,LCNL1,CHST15,TOMM40L,TESK2,SEMA6A,FGR,HPCAL4,MOBP,SELL,ERICH3,ANK1,GAS7,GPAM,MADD,MSRA,PDE8B,SPHKAP,NAXD,SLN,ASTN1,ADGRA1,IGSF9B,TMEM151A,ATP1A2,DKK3,SCN3B,KIF21B,ILDR2,ZSWIM8,B4GALNT1,TTLL9,ALDH1L1,SEPT3,SLCO1C1,ARHGEF7,VAMP1,NHLH1,C1QC,GNAS,CAMTA1,CDK5R2,BTRC,B4GALNT4,NUCB1,AKNA,GRIA4,CYB561A3,CRB1,TMEM25,FBXL16,PAH,TNFRSF1B,PADI2,TNS1,IGFN1,PIRT,PDYN,GPR37L1,ADGRG1,ASIC3,CHRNB2,DLGAP3,NRXN2,CPT1C,FADS2,CNTN1,CELF5,COL9A2,ACBD5,POU3F2,CRLS1,PPP2R5C,SNCAIP,PRKCZ,USP54,CTNND1,EDRF1,MASP1,WBP1L,ANKS1B,CNIH3,PRDM2,PRTFDC1,MAGI2,PLPPR4,SV2A,SRGAP3,KCNJ9,KCNK2,PCDH15,KCNN3,DLG2,NKAIN1,HS3ST4,RAB3IL1,SLC25A48,GOPC,GNE,L1CAM,BSDC1,SYT15,SIDT2,EFNA3,FGFBP3,ELAVL4,PRRT4,EPB41,BAALC" MicroRNA hsa-miR-147:mirSVR_lowEffct hsa-miR-147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.28E-51 5.02E-47 1.62E-48 1.49E-47 120 1736 "SERPINA3,ABAT,ZFYVE27,MAP6,ACHE,RTN3,EYA1,WLS,GALNT13,NLGN4X,TOMM40L,GPR158,LRRTM4,FGF1,FGF14,ACTL6B,ASIC4,HPCAL4,MOBP,FOXG1,NTNG1,SLITRK3,ZNF365,MIER1,URGCP,MADD,CCDC88A,CADPS,SLCO1A2,NAXD,ASTN1,SNAP25,ATP1A2,ATP2B2,SOX10,ZSWIM8,ENKUR,ARPP21,FXYD6,NFASC,NCAM1,BCL2L2,NDUFA5,NCDN,NELL1,ADHFE1,SEPT3,PCDH11X,UNC5D,MMD2,CACNA1A,CACNB2,GPR17,AZIN2,PCDHGA3,TMEM151B,GRID1,GRIK2,GRIK4,CRB1,GUCY1A2,TJP1,CDK11B,PCDH9,LGI1,PCSK2,MAGI1,TMPRSS5,CHGA,TLX1,JAM2,SLC22A6,CADM1,OPALIN,TJP2,FTO,CNTN1,CABP1,CELF5,SLC25A27,IFFO1,NSD2,FAAP20,NXPH1,ACBD5,MICAL2,OSBPL3,CHD5,NCAN,PRKAB2,RAB39A,PRKCG,CTNND2,FAM131B,BRINP3,SYNC,PTHLH,PRDM2,LRP8,PTPRO,SRGAP3,NTM,KCNMA1,DLG3,NKAIN1,HS3ST4,KLRC2,DNM2,DPP6,DSCAM,RASGRF1,GNE,DTNA,RGS7,SYT15,SEC61A2,ARHGAP12,EPB41,EPB41L2,UEVLD" MicroRNA hsa-miR-1226*:mirSVR_lowEffct hsa-miR-1226*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-50 6.28E-47 1.96E-48 1.80E-47 127 1961 "DPF1,MAG,ZFYVE27,ACER3,ACHE,SRARP,SYT9,CLIP1,CHST15,DRAXIN,TOMM40L,LRRTM4,FGF1,ASIC4,ELMOD1,FOXM1,SFPQ,ERICH3,CDC42BPA,APBA2,NTNG1,DGKZ,PAAF1,MIER1,PKNOX2,SLC6A9,SLC8A2,SLC8A3,NSG2,SLC14A1,DACH2,KBTBD12,TMEM108,PALLD,SCN3B,SON,ZSWIM8,B4GALNT1,ARPP21,NAP1L2,SPART,NFASC,NCAM1,BCL2L2,NDUFA5,GFAP,GFRA1,SEPT3,VAMP1,ZNF638,DCLK2,CAMTA1,BTRC,CNTN2,ADGRL3,GOLGB1,CACNA1A,GPM6A,NEU4,TCF12,CAMK2G,GRIA1,RFFL,CYB561A3,ATP13A2,TF,CRB1,PTPN5,ZDHHC22,TNS1,DCLK1,HRH3,BEST3,HPSE2,ASIC3,PLEKHB1,GDAP1L1,CAMKV,CPT1C,TJP2,FADS2,FLRT1,FTO,C11orf49,BEST1,NSD2,NXPH1,CNRIP1,MFSD4A,PNKD,CRLS1,TENM4,ATRNL1,NCAN,DZIP3,SDC3,PRKCZ,USP54,IGSF1,CTNND2,EDRF1,ECE2,WBP1L,TOMM20,BDNF-AS,PRDM2,HP1BP3,KCNA6,KCNC1,SV2A,PEX5,DLG2,KLRC3,SLC25A48,DNM2,SLC17A6,RAD52,SLC25A18,RASGRF1,GNE,L1CAM,RFX4,ZNF248,RNF220,SFXN5,RAVER2,PRRT4" MicroRNA hsa-miR-137:TargetScan hsa-miR-137 TargetScan 2.55E-50 1.38E-46 4.18E-48 3.83E-47 91 943 "EPS8,RIMKLA,CEND1,ACTN2,CSMD3,ADCY2,DSCAML1,AMER2,NLGN4X,GPR158,CDC42BPA,ANXA7,PPM1E,GPAM,ARHGAP5,CADPS,LGI3,ASPH,NRG3,ATP2B2,MEGF11,MYT1L,B3GALT2,GAD2,AHCYL1,FXYD6,NPAS3,NFASC,C11orf87,CLASP2,RCOR2,NEUROD1,FAM168A,NFIA,MLC1,LUZP2,DCLK2,ANO4,ACSL6,CACNB2,DIRAS1,GPR26,CAMK2A,GRIA1,GRIK3,GPR88,OPCML,PTPN5,GUCY1A2,REPS2,CDC42,FNDC5,HAPLN2,CHGA,NRXN1,NEGR1,FAT3,MED1,PPP2R5C,OSBPL3,RIMS4,RBPJ,PRKAB2,PKN2,PLD5,MAPK8,MAPK10,PROX1,RIMS3,JAKMIP2,PMEPA1,CADM2,KCNA1,KCNA2,CDH20,PTPRD,KCNC1,KCNH1,NKAIN1,CALN1,PLEKHB2,RASGRF1,ABCC9,FAM135B,EFNA3,RBM12,RAVER2,ELAVL3,EN2,PRRT4,RCAN2" MicroRNA hsa-miR-519c-3p:mirSVR_lowEffct hsa-miR-519c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-49 7.21E-46 2.12E-47 1.94E-46 120 1781 "EPS8,MAP6,MAPT,ACTN2,LDLRAD3,SLC25A25,CSMD3,CLIP1,WAC,SORCS1,AMER2,NLGN4X,TRIM46,SGIP1,CDC42BPA,PPM1E,DOCK10,MAGI3,GPAM,DGKD,TACC2,CLSTN1,MIER1,ARHGAP5,SHANK2,TAGLN3,MTR,SORCS3,SNAP25,USP33,TNIK,KIF21B,TTLL9,IDI2-AS1,GART,DNER,NAP1L2,NFASC,NCAM1,BCL2L2,NDUFA5,AJAP1,NFIA,MLC1,NHLH1,UNC5D,TMEM136,GPM6A,FAM69C,CACNA1E,CACNB2,ZEB1,AZIN2,NUDT21,CAMK2G,SYT6,GRIA1,SHISA7,CRB1,MFSD2A,GUCY1A1,ZFP91,KCNK10,PAX6,REPS2,PTGDR2,LGI1,PFKFB3,CASC2,TUB,MS4A7,DUSP26,CELF5,PRRX1,IFFO1,CNRIP1,MFSD4A,CHD1L,MED1,PNKD,KCNT2,FEZ2,ATRNL1,PRKCZ,NOS1AP,SYNC,PLPPR1,PRDM2,HP1BP3,CEP170,MAGI2,ZC3H11A,KCNA1,OCIAD1,PTPRD,KCNA6,PTPRE,SRGAP3,PCDH15,NAV2,DLG2,HS3ST4,C12orf4,SLC25A18,ABI1,GOPC,RASGRF1,FAM13C,DTNA,PAK5,BSDC1,TTLL7,SFXN5,SLC39A12,RPRD1A,BSCL2,C2orf80,TMEM100,EPB41,EPB41L1" MicroRNA hsa-miR-141:mirSVR_highEffct hsa-miR-141:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.37E-49 7.42E-46 2.12E-47 1.94E-46 115 1627 "EPS8,MAP6,LGR4,EYA1,ATAT1,MDM4,CSMD3,CLIP1,ADD3,ADORA3,SLC44A5,TESK2,LINC00461,ELMOD1,SLC30A10,SFPQ,ITSN1,DOCK10,SESN3,NTNG1,CCDC80,ST3GAL3,SHTN1,MIER1,SLC1A7,URGCP,CCDC88A,SLC14A1,ASPH,ASTN1,RCOR3,ATM,PHYHIPL,MEGF11,SON,MYT1L,SOX5,NEK6,NAP1L2,NPAS3,LMO3,CLASP2,ZNF302,AJAP1,GLS,PCDH11X,ZNF638,SYT4,CAMSAP2,ADGRL3,GPM6B,LILRA1,TCF7L2,ZEB1,TCF12,PTBP2,SYT6,BRSK2,GRIA2,GRIA4,ADAMTS8,PTPN5,ZFP91,HPS5,PCDH8,PCDH9,CDH10,TPD52,ACOT7,BEST3,HMGB1,PMP2,SPATA6,ACBD5,MED1,SF1,CRMP1,RNF14,KCNT2,ATRNL1,VCAN,NCAN,RBPJ,PRKACB,CTNND2,NRSN1,EDRF1,KIAA0408,ANKS1B,GON4L,SYNC,PTCH1,PTHLH,CEP170,PTPRD,PTPRE,KCNJ11,PEX5,SLC17A6,GOPC,GNE,FAM13C,DBX2,RTN4,SLC6A15,CAMK1G,NUP214,ATL1,ZNF248,TTLL7,SEC61A2,RBM12,RAVER2,ELAVL4,TMEM100" MicroRNA hsa-miR-630:mirSVR_lowEffct hsa-miR-630:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-49 9.79E-46 2.72E-47 2.50E-46 125 1946 "SYT9,CSMD2,ARID1A,CLIP1,PLEKHG5,GALNT13,FABP7,FCGR1A,GPR158,SCN3A,LRRTM4,LRRC7,UNC79,MOG,SOX6,SELL,RASA3,USP28,CNIH2,PPFIA1,ANXA7,APC,GPAM,ST8SIA1,SHTN1,ZNF365,RPH3A,SLC2A5,ARHGAP5,ARFGAP2,CCDC88A,ASPH,SORCS3,SMARCE1,RCOR3,ATM,ATP1A2,NRG3,PHYHIPL,DKK3,USP33,SON,IDI2-AS1,KIF1B,DNER,NPAS3,NCAM1,C11orf87,BCL2L2,STOX1,DCAF5,ADHFE1,ARHGEF7,POPDC3,LUZP2,ANO4,GPM6B,TCF7L2,ZEB1,PTBP2,VXN,VSTM2A,GRIA4,GRIK2,GRM3,CRB1,TMEM25,USP2,DAAM2,CDC42,PADI2,CDH8,PDE2A,PDE3B,PRMT8,PIRT,ANO5,TMEFF2,JAM2,HPCA,NLGN3,NRXN1,CNTN1,PRRX1,SLC36A4,NSD2,POU3F2,CRLS1,PPP2R5C,ATRNL1,RBPJ,PRKACB,KIAA1755,PKN2,FGFR1OP2,SYTL2,PLPPR5,ZNF385B,ITGAV,PLPPR1,PRTFDC1,CEP170,CSDE1,BLOC1S6,KCNA4,OCIAD1,KCNA6,PTPRE,RABGAP1L,KCNK1,KCNMA1,PEX5,DNAH9,PLEKHB2,RAD52,DBX2,DTNA,NUP214,RGS10,FAM135B,ATL1,SSPN,ARHGAP12,CBLN2,TMEM100" MicroRNA hsa-miR-671-5p:mirSVR_lowEffct hsa-miR-671-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.92E-49 1.04E-45 2.80E-47 2.57E-46 116 1663 "TTYH1,PRR5L,ZFYVE27,ACER3,EMID1,RTN3,CSMD2,SORCS1,ERMN,TOMM40L,SCN4B,FHL1,HPCAL4,PDZD4,FOXM1,SFPQ,ANK1,PI16,USP28,PPFIA1,ITSN1,DGKZ,ZCCHC17,ST3GAL3,URGCP,SLC2A5,SLC8A2,CADPS,SCMH1,ASCL1,CGREF1,SMARCE1,RCOR3,B3GAT1,TMEM151A,SNCB,ATP1A2,USP33,WDTC1,ZSWIM8,EMC1,ADAM15,KIF1B,FXYD6,NFASC,CLASP2,SMOC1,GFAP,INKA2,ADHFE1,NFIA,ROBO3,CAMTA1,GNG3,ANO4,TBX15,NEU4,CACNB2,HAP1,CAMK2G,NUCB1,GRIA1,GRIA2,GRIA4,CRB1,TMEM9,ZDHHC22,DAAM2,TNFRSF1B,IGSF21,HRH3,LGI1,ZMYND8,FNDC5,JAM2,A2ML1,C11orf49,MEAF6,CELF5,CRMP1,PTPA,SNCAIP,CSF3R,KIAA1755,CTNND1,MAPK10,EDRF1,KIAA0513,DPYSL5,GON4L,SPIRE1,ZNF385B,PRTFDC1,MED24,OCIAD1,KCNA6,PTPRE,NTM,RABGAP1L,DLG2,WIPF2,DNM2,PLEKHB2,FAM57B,ABI1,RASGRF1,DTNA,RTN4,RFX4,RGS7,ATL1,SYT15,CACNG7,EPB41L2,SEZ6,BAALC" MicroRNA hsa-miR-200a*:mirSVR_lowEffct hsa-miR-200a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-49 1.34E-45 3.52E-47 3.23E-46 117 1698 "EPS8,LOC100128239,MAPT,MBP,CSMD2,ARID1A,KCNIP2,CSMD3,F3,CLIP1,KLRC4,CDC7,SORCS1,NLGN4X,SLC44A5,FGF1,LRRC7,FGF14,SEMA6A,ELMOD1,SOX6,AMPH,SFPQ,ANK3,PPFIA1,PPM1E,SESN3,APC,CCDC80,DGKZ,SLITRK3,NLGN1,AQP4,LRRC55,CCDC88A,ASCL1,SLCO1A2,SLIT1,ASPH,SNAP25,ATM,ATP2B2,MYT1L,KIF21B,AHCYL1,NMNAT2,DNER,COLGALT2,BCL2L2,SEPT3,NFIA,ARHGEF7,PCDH11X,CNTN2,ADGRL3,GPM6A,GPM6B,CACNB2,PRLHR,ZEB1,TCF12,PTBP2,PCDHGA3,VXN,GRIA1,GRIA2,GRIK2,TLL2,DAAM2,PAX6,PCDH8,PCDH9,DCLK1,MAGI1,PDE3B,PDE4B,FNDC5,HERC2P3,HNRNPK,TMEFF2,NEGR1,ANLN,FTO,MEAF6,SNCAIP,ATRNL1,VCAN,PRKAB2,PRKACB,PUM1,KLK6,WBP1L,SYTL2,ZNF385B,CADM2,PRDM2,CEP170,BLOC1S6,KCNA4,PTPRE,PCDH15,DLG2,TMEM255A,ATN1,GOPC,FAM13C,DBX2,DTNA,ATL1,TTLL7,SSPN,ABI2,ARHGAP12,CBLN2,RAVER2,EPB41L1,BAALC" MicroRNA hsa-miR-636:mirSVR_lowEffct hsa-miR-636:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.18E-49 1.72E-45 4.32E-47 3.96E-46 112 1550 "EPS8,ACER3,LGR4,CSMD3,GALNT13,SORCS1,GPR158,LRRTM4,ASIC4,FGR,HPCAL4,MOG,ERICH3,PPFIA1,ITSN1,DGKZ,SLITRK3,API5,USP16,ZNF365,ARFGAP2,CCDC88A,SLCO1A2,DNAH17,SMARCE1,DKK3,USP33,SOX1,KIF21B,JPH4,LMO3,STOX1,NEUROD1,SEPT3,ARHGEF7,PCDH11X,ZNF638,SEMA4A,GNAS,GNG4,NODAL,UNC5D,PSRC1,TMEM136,LRIT2,TCF12,NRGN,VXN,GRIA1,RFFL,OPCML,TMEM25,LEFTY2,USP2,INA,TMEM257,PCDH8,DCLK1,MAGI1,PDYN,ADGRG1,CASC2,TUB,TMEFF2,HEPACAM,NRXN1,ANLN,CNTN1,PACSIN1,CNRIP1,POU3F2,SNCAIP,RGS6,MICAL2,OSBPL3,ATRNL1,DZIP3,RAB39A,PLD5,IGSF1,RIMS3,ANKS1B,JAKMIP2,CADM2,PRDM2,RGMA,CEP170,CSDE1,MAGI2,STMN4,ZC3H11A,SMG7,KCNK1,KCNK2,KCNN3,DLG3,KIF2A,HS3ST4,RAB3IL1,PID1,SLC17A6,DBX2,DTNA,PAK5,ZYG11B,JMJD1C,INSYN2,RNF220,SLC39A12,SSPN,EPB41L1,UEVLD" MicroRNA hsa-miR-33b:mirSVR_lowEffct hsa-miR-33b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.19E-49 1.73E-45 4.32E-47 3.96E-46 126 1989 "ABAT,MAP6,LGR4,MRVI1,MDM4,CSMD3,KLHL32,RTN1,KLRC4,SLITRK1,GALNT13,AMER2,CHST15,GPR158,LRRTM4,MOBP,SGIP1,ANK2,ANK3,ITSN1,PKP4,APBA2,APC,GPAM,CACHD1,NLGN1,API5,SFMBT2,SLC2A5,SHANK2,DACH2,TAGLN3,BRINP2,SMARCE1,RCOR3,EIF4G3,FYN,MYT1L,SOX5,CAB39,GAD2,AHCYL1,JPH4,NPAS3,NFASC,ERBIN,NELL1,NEUROD1,SEPT3,NFIA,GLS,SYT4,POPDC3,CAMSAP2,ADGRL3,WWC1,ANO4,TBX15,GPM6A,CACNB2,GPR19,TCF12,AZIN2,NUDT21,CAMK2G,GRIA1,GRIA2,GRIA4,OMG,OPCML,TMEM25,LEFTY2,TLL2,CDC42,TNS1,PCDH9,ZNF384,PDE4B,BEST3,CASC2,MS4A7,TMEFF2,NLGN3,KIAA1549L,NRXN1,SEMA5B,CELF5,PACSIN1,ACBD5,TENM4,KCNT2,DZIP3,SDC3,FMN2,RAB39A,IGSF1,FGFR1OP2,TOX,ANKS1B,SYNC,PRTFDC1,RGMA,CSDE1,PTPRO,NTM,KCNK1,KCNK2,PCDH15,KCNMA1,HS3ST4,WIPF2,DNAH9,PID1,KLRC3,FAM66C,SLC25A18,ABI1,GNE,DTNA,RTN4,RET,ATL1,ZNF248,SLC39A12,RPRD1A,RAVER2" MicroRNA hsa-miR-301a:mirSVR_highEffct hsa-miR-301a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.97E-49 3.77E-45 9.20E-47 8.44E-46 114 1623 "RABEPK,EPS8,SDE2,TMEM74,CNTNAP3,ACTN2,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,WAC,GPR158,TESK2,SCN3A,FGF14,MOG,ERICH3,USP28,APBB1,APC,SYBU,API5,AQP4,ZNF365,MIER1,BCO1,RUFY2,CCDC88A,SHANK2,SLC14A1,NAXD,CAPRIN2,MTR,TMEM108,SNAP25,NRG3,USP33,MYT1L,SOX5,B4GALNT1,TTLL9,TTC9B,SPART,CLASP2,NDUFA5,SMOC1,ERBIN,NEUROD1,NFIA,GLS,ZNF638,SYT4,LUZP2,DDHD2,CAMTA1,CAMSAP2,PRUNE2,GPM6A,CAMK2A,SYT6,GRIA2,GPR88,OMG,LINC00839,TGFBR3,TNFRSF1B,TNS1,PCDH9,TPM3,PDE1C,PDE3B,DUSP26,ZFYVE9,CCSER2,TJP2,ST8SIA5,CCDC136,BTF3L4,SLC36A4,ACBD5,POU3F2,CRLS1,PPP3CB,CHD5,USP54,ARHGEF4,NRSN1,FGFR1OP2,PSD,SYNC,SIRPA,PLPPR1,PMEPA1,PTHLH,LRP8,CEP170,CDH20,NTM,KCNJ11,KCNN3,CAB39L,RAB5B,PID1,ATG16L1,C12orf4,ABCC9,RET,SLC39A12,RBM12,RPRD1A,ARHGAP12,BAALC" MicroRNA hsa-miR-182:mirSVR_lowEffct hsa-miR-182:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-48 5.48E-45 1.31E-46 1.20E-45 124 1945 "EPS8,ACER3,CDHR1,PLEKHG5,GRAMD1B,SNX30,AMER2,FOXRED2,LRRTM4,SEMA6A,ASIC4,FHL1,SLC30A10,MOBP,ANK2,ITSN1,SESN3,SLITRK3,SYBU,ST3GAL3,ST8SIA1,BCAS1,AQP4,MIER1,MSR1,SLC6A9,ARHGAP5,SLC8A3,CCDC88A,ATM,FYN,ATP2B2,GABBR1,SON,ZCCHC24,NFASC,NCAM1,BCL2L2,NDUFA5,NEUROD1,AJAP1,GLS,PCDH11X,ZNF638,NKX2-2,KAZN,GNAS,DDHD2,MYRF,BTRC,ANO4,ACSL6,TCF12,AZIN2,PTBP2,GRIK2,CRB1,GUCY1A1,TMEM257,REPS2,PADI2,TNS1,PCDH9,PDE1C,PRMT8,PIRT,ANO5,TUB,TMEFF2,GDAP1L1,NRXN1,NMT2,CCSER2,VAV2,PRRX1,NSD2,FAT3,PNKD,CRLS1,TENM4,PPP3CB,ATRNL1,RBPJ,PKN2,MAPK10,TOX,KIAA0513,PLPPR5,COPS7A,KCNA6,PLPPR4,AK5,KCNJ10,PCDH15,NAV2,PEX5,SNX27,DLG3,NKAIN1,WIPF2,RAB5B,KLRC2,RALGDS,ATN1,RASGRF1,DTNA,NUP214,ZNF248,VANGL2,SYT15,SEC61A2,SFXN5,SSPN,SIDT2,RBM12,RERGL,VWA5A,FGFBP3,ARHGAP12,SLC4A10,ELAVL4,EPB41,EPB41L2,BAALC" MicroRNA hsa-miR-576-3p:mirSVR_lowEffct hsa-miR-576-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-48 5.89E-45 1.37E-46 1.26E-45 125 1979 "EPS8,ABAT,ACER3,CDHR1,RCSD1,ACTN2,ATAT1,KCNIP2,ADAR,ADCY2,RXRG,SORCS1,GRAMD1B,LRRTM4,LINC00461,LRRC7,ASIC4,BCAR3,FHL1,HPCAL4,MOBP,SOX6,TRIM46,ANK1,PPFIA1,ANXA7,PKP4,APBA2,SORBS1,ST3GAL3,JAKMIP3,USP16,MIER1,MSRA,ARHGAP5,SLC8A3,CGREF1,SCG3,ASPH,SORCS3,TMEM108,PHYHIPL,DKK3,SON,SOX5,AHCYL1,NMNAT2,MYH7,ADAM15,NCAM1,C11orf87,CASTOR3,SYT4,LUZP2,ANO4,LILRA1,TCF7L2,PTBP2,GRIA1,GRIA4,OMG,OPCML,TGFBR3,GUCY1A2,ZFP91,MAEL,CDH8,TPD52,PDE3B,LINC01102,PDYN,ASIC3,CASC2,PIK3CD,CCSER2,FADS2,FTO,IFFO1,PPP3CB,RGS6,MICAL2,ATRNL1,PRKACB,DZIP3,FMN2,PLPP4,PLD5,CTNND1,MAPK10,KIAA0408,TOX,SYTL2,ZNF385B,SYNC,DNAJC6,PTHLH,STMN4,BLOC1S6,OCIAD1,SMG7,PTPRE,PTPRO,C1orf109,SV2A,NTM,RABGAP1L,CCDC3,PEX5,KLRC3,DNM2,DPP6,DTNA,ABCC9,ZYG11B,RGS7,INSYN2,ARHGEF10L,SEC61A2,SLC39A12,SH3GLB1,ABI2,SLC4A10,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-376c:mirSVR_lowEffct hsa-miR-376c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-48 1.28E-44 2.91E-46 2.67E-45 116 1705 "RABEPK,SDE2,MAP6,ASIC1,ATAT1,LDLRAD3,CSMD3,F3,CLIP1,DSCAML1,SORCS1,FCGR1A,SCN3A,KIAA1109,SOX6,AMPH,SFPQ,ERICH3,ANK1,PPFIA1,PPM1E,APC,SLC1A2,ZNF365,LRRC55,SHANK2,SCG3,TMEM108,IGSF9B,FYN,SON,MYT1L,TTLL9,CPLX2,ALDH1L1,DCAF5,PCDH11X,NHLH1,LUZP2,KAZN,ROBO3,CAMSAP2,KLHL4,ANO4,FAM69C,ZEB1,CLEC9A,EML4,PSD3,RFFL,GRIK2,GRIN1,OMG,CRB1,AIFM1,CELF3,PAX6,REPS2,PCDH8,DCLK1,PTGDR2,RBFOX2,PDE4B,CIART,HMGB1,LRTM2,TLX1,SERPINE2,ZFYVE9,ANLN,A2ML1,CCSER2,BEST1,PRRX1,SPATA6,FAT3,ACBD5,POU3F2,MED1,PPP2R5C,NCAN,DZIP3,PLPP4,NOS1AP,KIAA0408,ZBTB16,RIMS3,TOMM20,ZNF385B,PTCH1,PTHLH,CADM2,PRDM2,HP1BP3,COPS7A,CEP170,KCNA2,KCNA4,PTPRD,PTPRZ1,SRGAP3,KCNJ10,PEX5,WIPF2,PID1,DBX2,RTN4,RET,RGS7,FAM135B,SSPN,PIANP,SH3GLB1,SLC4A10,TMEM100,EPB41L2" MicroRNA hsa-miR-18a*:mirSVR_lowEffct hsa-miR-18a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-48 1.86E-44 4.13E-46 3.79E-45 121 1870 "LOC100128239,CDHR1,SYT9,DUSP27,PAQR6,CEND1,MRVI1,CSMD2,RTKN,SLC25A25,ADAR,ADCY2,ADD3,FABP7,SNX32,ASIC4,HPCAL4,SFPQ,CDC42BPA,ANK1,ANK2,ANK3,PPFIA1,MAGI3,DGKD,ST3GAL3,SHTN1,URGCP,PKNOX2,ARFGAP2,SLC8A2,NSG2,SCMH1,CGREF1,SLCO1A2,SORCS3,ASTN1,ADGRA1,TMEM151A,CCDC181,PALLD,MEGF11,DKK3,GABBR1,ZSWIM8,NMNAT2,NEK6,ADAM15,NFASC,BCL2L2,SMOC1,GPR162,INKA2,RCOR2,HEPN1,KIRREL3,GJB1,ADHFE1,AJAP1,ARHGEF7,VAMP1,OS9,MYRF,UNC5D,ADGRL3,GOLGB1,PRUNE2,WSCD1,AZIN2,PTBP2,PCDHGA3,GRIK4,ADAMTS8,SPX,TGFBR3,P2RX7,ZDHHC22,DAAM2,TNS1,PTGDR2,PDE2A,PDE4B,TMEFF2,ZFYVE9,SEMA5B,OPALIN,FTO,CCDC136,SLC25A27,MFSD4A,CHD1L,PTPA,NKAIN4,RIMS4,RBPJ,PRKAB2,DOCK7,FMN2,USP54,NRSN1,WBP1L,PTAFR,PMEPA1,PLPPR4,PTPRO,SRGAP3,KCNJ9,CCDC3,KCNK1,PCDH15,WIPF2,TMEM255A,ABCC9,CAMK1G,RFX5,FAM135B,ZNF248,EFNA3,EPB41,RASGRP2,BAALC" MicroRNA hsa-miR-2116*:mirSVR_lowEffct hsa-miR-2116*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-48 2.23E-44 4.84E-46 4.44E-45 112 1591 "SDE2,LOC100128239,PRR5L,MAPT,MBP,PAQR6,CSMD3,F3,ERMN,FGF1,LRRC7,PDZD4,SOX6,AMPH,ASRGL1,ANK1,PKP4,APBB1,DOCK10,GPAM,DGKD,ZCCHC17,ZNF365,SLC1A7,NBPF1,SLC14A1,CAPRIN2,BRINP2,RCOR3,SNCB,MEGF11,B3GALT2,CAB39,ARPP21,NFASC,CLASP2,BCL2L2,STOX1,POPDC3,DCLK2,UNC5D,GOLGB1,LILRA1,ZEB1,PTBP2,CECR2,TMEM151B,VXN,GRIA4,RFFL,GPR88,INA,TMEM9,CELF3,ZDHHC22,ZFP91,TNFRSF1B,REPS2,HPS5,CDH8,PDE2A,IGFN1,PIRT,ZMYND8,BEST3,TMPRSS5,PFKFB3,ZFYVE9,UBTF,A2ML1,PMP2,MEAF6,SPATA6,POU3F2,SNCAIP,FEZ2,FEZ1,IGSF1,CTNND1,CTNND2,PUM1,NOS1AP,ZBTB16,PLPPR5,ITGAV,BDNF-AS,CNIH3,BLOC1S6,PTPRE,PTPRO,C1orf109,SRGAP3,NTM,RABGAP1L,WIPF2,FAM13C,ABCC9,ZYG11B,FAM135B,ARHGEF10L,ZNF248,RNF220,CACNG7,PIANP,RPRD1A,GPR61,LMO1,ABI2,VWA5A,ELAVL4,RPE65,TMEM100" MicroRNA hsa-miR-605:mirSVR_lowEffct hsa-miR-605:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.93E-48 3.21E-44 6.83E-46 6.27E-45 123 1945 "TTYH1,LGR4,SYNDIG1,EYA1,ATAT1,LDLRAD3,ADAR,RXRG,ERMN,ADORA3,NLGN4X,AGT,SCN3A,LRRC7,HPCAL4,MOBP,MOG,ERICH3,RASA3,PPFIA1,ITSN1,DOCK10,NTNG1,TACC2,NLGN1,JAKMIP3,API5,SHTN1,PAAF1,AQP4,MIER1,SLC1A6,SLC2A5,PKNOX2,ARHGAP5,ASPH,MTR,ALDH4A1,ATP2B2,MYBPC1,SOX5,AHCYL1,B4GALNT1,NAP1L2,SPART,LMO3,BCL2L2,NDUFA5,RCOR2,RGL1,SLCO1C1,NFIA,VAMP1,ZNF638,ROBO3,CAMTA1,CACNA1A,PRUNE2,CACNA1E,ZEB1,VSTM2A,NUMA1,GRID1,CRB1,TJP1,ZDHHC22,PCDH9,ZNF384,FNDC5,MS4A7,CADM1,TJP2,VAV2,BTF3L4,SPATA6,SLC36A4,ACBD5,MFSD4A,POU3F2,CRLS1,PTPA,PPP3CB,ATRNL1,VCAN,PRKAB2,PRKCG,PLD5,IGSF1,CTNND1,FAM131B,ECE2,TOMM20,LRRTM3,SIRPA,ITGAV,CEP170,OLFM3,OCIAD1,PLPPR4,PTPRO,NTM,RABGAP1L,TMCC2,KCNK1,RAB3IL1,SLC25A48,SLC17A6,RAD52,FAM66C,PARP11,ATG16L1,SLC25A18,DSCAM,BEND5,RTN4,ZYG11B,NUP214,RFX5,VANGL2,SEC61A2,CBLN2,EPB41,BAALC" MicroRNA hsa-miR-429:mirSVR_highEffct hsa-miR-429:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.15E-47 6.23E-44 1.30E-45 1.19E-44 121 1892 "EPS8,SDE2,ABAT,ACER3,ACHE,LDLRAD3,ARID1A,CSMD3,CLIP1,SLITRK1,ADD3,CDC7,ERMN,AMER2,NLGN4X,GPR158,TESK2,FHL1,ELMOD1,FOXG1,ERICH3,SGIP1,PPFIA1,ITSN1,PKP4,AQP4,ZNF365,SLC8A3,SLC14A1,SLIT1,CAPRIN2,ASPH,SORCS3,SMARCE1,SNAP25,FYN,SOX1,ZCCHC24,KIF21B,CAB39,ENKUR,ARPP21,KIF1B,GART,NAP1L2,SPART,C11orf87,CLASP2,ZNF302,RGL1,PHLDB1,GLS,VAMP1,CAMSAP2,MMD2,ADGRL3,TMEM136,GPM6A,CACNB2,ZEB1,PTBP2,CECR2,AKNA,GRIA2,GRIA4,PTPN5,TGFBR3,TLL2,HPS5,CDC42,PCDH8,ARHGAP19,PCSK2,PDE4B,HMGB1,HNRNPK,TMEFF2,SERPINE2,NRXN1,NEGR1,ANLN,A2ML1,TJP2,SLC25A27,BTF3L4,COL9A2,NXPH1,CSF3R,FEZ2,PHACTR3,PRKACB,IGSF1,CTNND2,BRINP3,WBP1L,SYNC,LRRTM3,SIRPA,PTCH1,PLPPR1,BDNF-AS,PTHLH,PRDM2,PRTFDC1,BLOC1S6,OCIAD1,PTPRD,PLPPR4,PTPRZ1,ARNT2,FAM13C,DTNA,PAK5,ABCC9,ATL1,ZNF248,RLBP1,SEC61A2,RPRD1A,RAVER2,SLC4A10" MicroRNA hsa-miR-33b*:mirSVR_lowEffct hsa-miR-33b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-47 8.24E-44 1.68E-45 1.54E-44 103 1345 "EMID1,SYT9,FAM43B,LDLRAD3,CSMD3,ADCY2,ADORA1,NLGN4X,DRAXIN,GPR158,HOGA1,TESK2,KIAA1109,FGF1,SLC30A10,FOLH1,PKP4,APBB1,APC,MAGI3,SORBS1,SHTN1,CLSTN1,SLC1A7,MSR1,LRRC55,ARFGAP2,YPEL4,SCMH1,PDE8B,NAXD,CAPRIN2,MTR,RCOR3,ADGRA1,NRG3,B3GALT2,TNIK,CAB39,NMNAT2,JPH4,EMC1,C11orf87,STOX1,DCAF5,ADHFE1,MLC1,CDK5R2,FAM69C,AZIN2,VXN,GRIA1,GRID1,GRIN1,LINC00839,CRB1,IGSF21,PADI2,PTGDR2,LGI1,MAGI1,PDYN,CHGA,ASIC3,CASC2,HERC2P3,HEPACAM,DLGAP3,CADM1,UBTF,TJP2,ST8SIA5,SLC36A4,FAT3,SNCAIP,PPP3CB,RGS6,FEZ2,FEZ1,VCAN,DOCK7,IGSF1,EDRF1,DPYSL5,GON4L,ELMO1,PRDM2,CEP170,CSDE1,KCNA1,OCIAD1,PTPRE,SV2A,NTM,KCNJ11,KCNK1,KCNK2,SNX27,TMEM255A,RTN4,BSDC1,NUP214,FGFBP3" MicroRNA hsa-miR-1229:mirSVR_lowEffct hsa-miR-1229:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-47 1.25E-43 2.50E-45 2.29E-44 109 1528 "ZFYVE27,MAP6,MAPT,CDHR1,SYT9,IL17D,LDLRAD3,KCNIP2,CLIP1,RTN1,ADD3,SORCS1,TOMM40L,LINC00461,SEMA6C,ASRGL1,PPFIA1,ITSN1,NTNG1,GPAM,RUFY2,SLCO1A2,ASPH,DDX25,TMEM108,TMEM151A,ATP2B2,TNIK,CADM3,ZSWIM8,ARPP21,SALL3,ADAM15,CPLX2,NAP1L2,FXYD6,SPART,NFASC,C11orf87,COLGALT2,SMOC1,DCAF5,AJAP1,RHBDL3,ZNF638,SYT4,DCLK2,CAMTA1,WWC1,DIRAS1,VXN,NUMA1,GRIA2,GRID1,GRIK3,TF,OPCML,FBXL16,KCNK10,SEZ6L,LGI1,PDE1C,PDE2A,PDE3B,IGFN1,ANO5,HEPACAM,ANLN,SULT4A1,ACBD5,POU3F2,CRLS1,NKAIN4,FEZ2,VCAN,FMN2,IGSF1,KIAA0513,TOMM20,CNIH3,LRP8,BLOC1S6,KCNA1,OCIAD1,SMG7,C1orf109,SV2A,KCNJ10,PCDH15,DLG2,DLG3,NKAIN1,RAB5B,SLC25A48,SLC17A6,ATG16L1,ATN1,GOPC,PAK5,JMJD1C,FAM135B,ARHGEF10L,SYT15,SEC61A2,RBM12,GPR61,ABI2,FGFBP3,YY1AP1" MicroRNA hsa-miR-129-5p:mirSVR_highEffct hsa-miR-129-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.79E-47 2.59E-43 5.08E-45 4.66E-44 116 1757 "ACER3,FAM43B,SLC25A25,CSMD3,F3,KLHL32,ADD3,ERMN,KIAA1109,SEMA6A,ASIC4,FHL1,MOBP,AMPH,CDC42BPA,ANK2,ANK3,PPFIA1,ITSN1,SESN3,APC,MAGI3,NLGN1,LRRC4C,MIER1,RPH3A,SLC8A3,CCDC88A,CSPG5,ASPH,SMARCE1,EIF4G3,ATP2B2,MEGF11,DKK3,MYT1L,CADM3,CAB39,NMNAT2,ENKUR,JPH4,TTLL9,ERBIN,NELL1,ADHFE1,GLS,VAMP1,PCDH11X,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,CACNB2,VXN,GRIK2,GRM3,CRB1,TMEM257,PAX6,PCDH9,CDH8,LGI1,PCSK2,MAGI1,PDE1A,FNDC5,BEST3,HMGB1,HNRNPK,CADM1,NRXN1,NRXN2,CCSER2,C11orf49,SLC25A27,FAT3,CHD1L,VCAN,RBPJ,DOCK7,FMN2,PLPP4,USP54,NOS1AP,MASP1,TOX,ANKS1B,SPIRE1,SYNC,PMEPA1,CEP170,ZC3H11A,PLPPR4,PTPRZ1,NTM,AK5,KCNK1,PCDH15,WIPF2,SLC17A6,RALGDS,SLC25A18,ABI1,DTNA,PAK5,ABCC9,RET,RGS7,FAM135B,ARHGEF10L,RBM12,RPRD1A,FGFBP3,ELAVL4,OLIG2" MicroRNA hsa-miR-135a-5p:TargetScan hsa-miR-135a-5p TargetScan 5.62E-47 3.04E-43 5.74E-45 5.27E-44 73 609 "DPF1,ABAT,RIMKLA,EYA1,MDM4,ADARB2,GALNT13,ADCYAP1R1,GPR158,ANK3,ANXA7,PPM1E,APC,NTNG1,GAS7,PDE8B,ASPH,ATP2B2,MEGF11,MYT1L,CADM3,ILDR2,AHCYL1,B4GALNT1,CPLX2,BCL2L2,RGL1,ARHGEF7,GNG3,BTRC,CNDP1,ANO4,PRUNE2,GPM6B,CACNA1E,PTBP2,PSD3,GRIK3,FBXL16,GUCY1A2,HPS5,PCDH9,DCLK1,RBFOX2,ARHGAP19,PDE1C,PDE3B,FNDC5,ANO5,GDAP1L1,CADM1,NEGR1,CCSER2,FTO,MED1,PPP2R5C,ATRNL1,ARHGEF4,NRSN1,MAPK10,NOS1AP,ITGAV,JAKMIP2,CEP170,PTPRD,KCNN3,DLG2,RAB5B,CALN1,DTNA,CAMK1G,ABI2,RAVER2" MicroRNA hsa-miR-135b-5p:TargetScan hsa-miR-135b-5p TargetScan 5.62E-47 3.04E-43 5.74E-45 5.27E-44 73 609 "DPF1,ABAT,RIMKLA,EYA1,MDM4,ADARB2,GALNT13,ADCYAP1R1,GPR158,ANK3,ANXA7,PPM1E,APC,NTNG1,GAS7,PDE8B,ASPH,ATP2B2,MEGF11,MYT1L,CADM3,ILDR2,AHCYL1,B4GALNT1,CPLX2,BCL2L2,RGL1,ARHGEF7,GNG3,BTRC,CNDP1,ANO4,PRUNE2,GPM6B,CACNA1E,PTBP2,PSD3,GRIK3,FBXL16,GUCY1A2,HPS5,PCDH9,DCLK1,RBFOX2,ARHGAP19,PDE1C,PDE3B,FNDC5,ANO5,GDAP1L1,CADM1,NEGR1,CCSER2,FTO,MED1,PPP2R5C,ATRNL1,ARHGEF4,NRSN1,MAPK10,NOS1AP,ITGAV,JAKMIP2,CEP170,PTPRD,KCNN3,DLG2,RAB5B,CALN1,DTNA,CAMK1G,ABI2,RAVER2" MicroRNA hsa-miR-377:mirSVR_highEffct hsa-miR-377:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.22E-47 3.37E-43 6.16E-45 5.65E-44 112 1636 "DPF1,SYT9,ARID1A,SORCS1,SLC30A10,ZCCHC17,NLGN1,BCAS1,PAAF1,ZNF365,MIER1,RPH3A,MADD,MSR1,MSRA,ARHGAP5,ASTN1,PALLD,SON,ILDR2,GAD2,ZSWIM8,AHCYL1,ARPP21,EMC1,SALL3,NPAS3,NCAM1,CLASP2,NELL1,AJAP1,GLS,PCDH11X,ZNF638,DCLK2,NKX2-2,GNAS,CAMTA1,UNC5D,ADGRL3,PRUNE2,GPM6B,CACNB2,TCF7L2,ZEB1,TCF12,PTBP2,GRIA1,GRIA4,GPR88,TF,INA,PADI2,PCDH8,TPM4,PCSK2,PRMT8,PDE4B,CIART,CASC2,HERC2P3,TMEFF2,DUSP26,GDAP1L1,CADM1,NEGR1,CCSER2,NSD2,ACBD5,POU3F2,RBPJ,DZIP3,CTNND2,PUM1,FGFR1OP2,TOX,PLPPR5,PTCH1,DNAJC6,ELMO1,HP1BP3,LRP8,MAGI2,STMN4,KCNA2,KCNA4,KCNA6,SMG7,PLPPR4,PTPRO,NTM,KCNJ11,KCNMA1,DLG2,CAB39L,KIF2A,WIPF2,KLRC2,C12orf4,GNE,DTNA,ABCC9,SLC6A15,CAMK1G,ARHGEF10L,TTLL7,SEC61A2,SFXN5,RBM12,VWA5A,SLC4A10,EPB41" MicroRNA hsa-miR-367*:mirSVR_lowEffct hsa-miR-367*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.25E-47 3.39E-43 6.16E-45 5.65E-44 115 1730 "RABEPK,TTYH1,EPS8,MAP6,TMEM74,MBP,SYT9,RCSD1,ADGRV1,EYA1,WLS,GALNT13,GRAMD1B,ADORA1,SNX30,ADORA3,LRRTM4,LINC00461,FGF1,ASRGL1,ANK3,ITSN1,PKP4,APC,NTNG1,DGKZ,ZCCHC17,ZNF365,SLC1A6,SLC1A7,RUFY2,NSG2,SLC14A1,SNAP25,NRG3,DKK3,KIF1B,NPAS3,NFASC,ADHFE1,VAMP1,POPDC3,WWC1,ANO4,VWC2,TCF7L2,GPR19,TCF12,NUDT21,CAMK2G,GRIA2,LINC00839,TMEM25,TNFRSF1B,TNR,PCDH9,PTGDR2,LGI1,PDE3B,HMGB1,HPSE2,CHRM1,CASC2,NLGN3,GDAP1L1,SEMA5B,NEGR1,TJP2,PLXNB3,PMP2,SLC36A4,POU3F2,PPP2R5C,SNCAIP,TENM4,RGS6,ATRNL1,PHACTR3,RBPJ,KIAA1755,NRSN1,MAPK8,MASP1,SYTL2,ANKS1B,PHYHIP,PTAFR,PTHLH,PRDM2,KCNA6,SMG7,PTPRE,KCNC1,PTPRO,SV2A,TMCC2,KCNK1,KCNMA1,KCNN3,SLC17A6,DPP6,C12orf4,FAM13C,DBX2,DTNA,ABCC9,NUP214,RET,INSYN2,SEC61A2,RBM12,RPRD1A,CBLN2,EPB41,UEVLD" MicroRNA hsa-miR-3125:mirSVR_highEffct hsa-miR-3125:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.86E-47 4.26E-43 7.60E-45 6.97E-44 115 1734 "TTYH1,SDE2,MEG3,ARID1A,CSMD3,ADCY2,SLITRK1,RXRG,FABP7,SORCS1,ERMN,AMER2,SLC44A5,LRRTM4,FGF14,FHL1,ELMOD1,FOXM1,ASRGL1,ANK2,SESN3,APC,SORBS1,API5,ZNF365,MIER1,RUFY2,SLC8A3,DLL3,ASPH,ASTN1,SON,TNIK,CADM3,AHCYL1,ARPP21,KIF1B,NPAS3,C11orf87,STOX1,NEUROD1,GANAB,SEPT3,GLS,ASTN2,ADGRL3,KLHL4,ANO4,LILRA1,PTBP2,LINC00839,CRB1,LEFTY2,MFSD2A,TLL2,TMEM257,CDC42,PCDH9,ZNF384,PDE1C,PRMT8,PDE4B,PDYN,ZMYND8,BEST3,HMGB1,CHGA,CHI3L2,PLEKHB1,HNRNPK,KIAA1549L,ST8SIA5,BTF3L4,NXPH1,ACBD5,MED1,SF1,CRMP1,RNF14,PPP2R5C,SNCAIP,PPP3CB,RBPJ,CMTM5,PKN2,IGSF1,FGFR1OP2,GON4L,PLPPR5,LRRTM3,PTCH1,PMEPA1,PRTFDC1,COPS7A,MED24,SMG7,PTPRE,PTPRZ1,KCNK2,DNAH9,DNM2,C12orf4,RASGRF1,GNE,FAM13C,ABCC9,RET,RGS7,RGS10,INSYN2,TTLL7,VWA5A,OLIG2,RPE65,EPB41L1" MicroRNA hsa-miR-764:mirSVR_lowEffct hsa-miR-764:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.31E-47 5.04E-43 8.84E-45 8.11E-44 120 1898 "MAG,RABEPK,MBP,MRVI1,LDLRAD3,ARID1A,CSMD3,ADAR,KLHL32,SORCS1,ADORA1,DRAXIN,LRRTM4,SCNN1D,HPCAL4,TRIM46,ANK2,RASA3,DGKZ,GPAM,NLGN1,KIAA1614,PKNOX2,SLC8A3,MT3,NSG2,DACH2,CGREF1,GPR153,SCG3,LGI3,DNAH17,TAGLN3,DLL3,SLN,BRINP2,SORCS3,ASTN1,B3GAT1,TMEM108,ADGRA1,ATM,EIF4G3,ZSWIM8,ADAM15,KIF1B,CLASP2,ALDH1L1,KIRREL3,SEPT3,FAM168A,KAZN,ROBO3,CAMTA1,CDK5R2,MMD2,PSRC1,ADGRL3,TMEM136,TBX15,GPM6A,ACSL6,DDR1,AKNA,GRIA2,GRM3,CRB1,TGFBR3,USP2,P2RX7,DAAM2,PAX6,TNFRSF1B,CDC42,HRH3,PRMT8,PIRT,HMGB1,ASIC3,CASC2,JAM2,CPT1C,SULT4A1,MEAF6,NXPH1,CP,CHD1L,PPP3CB,ATRNL1,PRKCG,PLD5,IGSF1,KLK6,PSD,SPIRE1,SYNC,DKFZp779M0652,MED24,BLOC1S6,KCNA2,KCNA4,SMG7,PTPRE,KCND3,KCNJ11,KCNK2,DLG2,DLG3,KIF2A,HS3ST4,TMEM255A,DNM2,RAD52,C12orf4,RAP1GAP,BSDC1,ABCC9,PHC2,ZNF248,EPB41L1" MicroRNA hsa-miR-802:mirSVR_highEffct hsa-miR-802:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.92E-47 5.37E-43 9.26E-45 8.50E-44 121 1932 "EPS8,ACER3,CNTNAP3,F3,KLHL32,RTN1,WAC,FABP7,SLC44A5,HOGA1,SCN3A,LINC00461,FGF1,FGF14,BCAR3,PPFIA1,APC,MAGI3,NLGN1,JAKMIP3,ZNF365,MIER1,RUFY2,ARHGAP5,CCDC88A,SLC14A1,DACH2,MTR,SORCS3,SMARCE1,TMEM108,ATP2B2,DKK3,SOX5,CAB39,ENKUR,NAP1L2,NPAS3,NFASC,NCAM1,CLASP2,COLGALT2,NDUFA5,NELL1,NEUROD1,SEPT3,GLS,ZNF638,SYT4,DDHD2,UNC5D,ADGRL3,WWC1,TMEM136,ANO4,PRUNE2,GPM6A,NPPA,LILRA1,TCF7L2,GPR19,PTBP2,CAMK2A,NUMA1,GRIA4,RFFL,GRIK2,TMEM25,TJP1,PCDH9,LGI1,PDE3B,JAM2,NLGN3,ZFYVE9,KIAA1549L,ANLN,UBTF,NMT2,SULT4A1,PMP2,BTF3L4,CP,SF1,CRMP1,PPP3CB,ATRNL1,RBPJ,PRKAB2,PRKACB,CTNND1,CTNND2,PUM1,EDRF1,LRRTM3,PTCH1,CA10,HP1BP3,MAGI2,BLOC1S6,KCNA4,PTPRE,PTPRO,PTPRZ1,SV2A,KCNJ11,KCNK1,PCDH15,TMEM255A,DPP6,RALGDS,GOPC,GNE,PAK5,SLC6A15,JMJD1C,FAM135B,SEC61A2,SSPN,RPRD1A,EPB41" MicroRNA hsa-miR-200a:mirSVR_highEffct hsa-miR-200a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.08E-46 5.86E-43 9.92E-45 9.10E-44 109 1553 "LGR4,EYA1,ATAT1,MDM4,CSMD3,CLIP1,ADD3,ADORA3,SLC44A5,TESK2,LINC00461,ELMOD1,SLC30A10,SFPQ,ITSN1,DOCK10,SESN3,NTNG1,CCDC80,ST3GAL3,SHTN1,MIER1,SLC1A7,URGCP,CCDC88A,SLC14A1,ASPH,ASTN1,RCOR3,ATM,PHYHIPL,MEGF11,SON,MYT1L,SOX5,NEK6,NAP1L2,NPAS3,LMO3,CLASP2,ZNF302,AJAP1,GLS,PCDH11X,ZNF638,SYT4,CAMSAP2,ADGRL3,LILRA1,TCF7L2,ZEB1,TCF12,PTBP2,SYT6,BRSK2,GRIA2,GRIA4,ADAMTS8,ZFP91,HPS5,PCDH8,PCDH9,CDH10,ACOT7,BEST3,HMGB1,CADM1,PMP2,SPATA6,ACBD5,MED1,SF1,CRMP1,KCNT2,ATRNL1,VCAN,NCAN,RBPJ,PRKACB,CTNND2,NRSN1,EDRF1,KIAA0408,SYTL2,ANKS1B,GON4L,SYNC,PTCH1,PTHLH,CEP170,PTPRD,PTPRE,KCNJ11,PEX5,SLC17A6,GNE,FAM13C,DBX2,SLC6A15,CAMK1G,NUP214,JMJD1C,ATL1,ZNF248,TTLL7,RBM12,RAVER2,ELAVL4,TMEM100" MicroRNA hsa-miR-520d-5p:PITA hsa-miR-520d-5p:PITA_TOP PITA 1.17E-46 6.31E-43 1.04E-44 9.50E-44 86 915 "MAPT,LGR4,CSMD3,NLGN4X,UNC79,SOX6,MAGI3,SLITRK3,TACC2,SORBS1,NLGN1,API5,SLC1A2,CCDC88A,ATP2B2,PALLD,SON,MYT1L,ZCCHC24,CAB39,NKX6-2,CPLX2,NCAM1,LMO3,ERBIN,NFIA,GPM6A,TCF7L2,GRIA2,GRID1,TJP1,ZFP91,CDC42,PCDH9,RBFOX2,TPM3,PDE2A,PFKFB3,HNRNPK,JAM2,HEPACAM,NLGN3,CADM1,NEGR1,TJP2,MEAF6,PRRX1,CNRIP1,CRMP1,OSBPL3,CHD5,PKN2,PUM1,HES5,KIAA0408,PSD,LRRTM3,DNAJC6,CA10,LRP8,CSDE1,KCNA1,PTPRD,SMG7,PTPRE,PTPRO,PEX5,KIF2A,RAB5B,SLC17A6,FAM13C,PAK5,BSDC1,JMJD1C,RGS7,FAM135B,INSYN2,RNF220,RBM12,SH3GLB1,ARHGAP12,SLC4A10,EPB41,EPB41L2,RCAN2,SEZ6" MicroRNA hsa-miR-524-5p:PITA hsa-miR-524-5p:PITA_TOP PITA 1.17E-46 6.31E-43 1.04E-44 9.50E-44 86 915 "MAPT,LGR4,CSMD3,NLGN4X,UNC79,SOX6,MAGI3,SLITRK3,TACC2,SORBS1,NLGN1,API5,SLC1A2,CCDC88A,ATP2B2,PALLD,SON,MYT1L,ZCCHC24,CAB39,NKX6-2,CPLX2,NCAM1,LMO3,ERBIN,NFIA,GPM6A,TCF7L2,GRIA2,GRID1,TJP1,ZFP91,CDC42,PCDH9,RBFOX2,TPM3,PDE2A,PFKFB3,HNRNPK,JAM2,HEPACAM,NLGN3,CADM1,NEGR1,TJP2,MEAF6,PRRX1,CNRIP1,CRMP1,OSBPL3,CHD5,PKN2,PUM1,HES5,KIAA0408,PSD,LRRTM3,DNAJC6,CA10,LRP8,CSDE1,KCNA1,PTPRD,SMG7,PTPRE,PTPRO,PEX5,KIF2A,RAB5B,SLC17A6,FAM13C,PAK5,BSDC1,JMJD1C,RGS7,FAM135B,INSYN2,RNF220,RBM12,SH3GLB1,ARHGAP12,SLC4A10,EPB41,EPB41L2,RCAN2,SEZ6" MicroRNA hsa-miR-493:mirSVR_lowEffct hsa-miR-493:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-46 8.16E-43 1.32E-44 1.21E-43 112 1651 "EPS8,SERPINA3,SDE2,PRR5L,RTN3,LDLRAD3,ADAR,ADD3,ADORA1,TUBB4A,NLGN4X,FCGR1A,TESK2,ASIC4,GOLGA7B,ELMOD1,SFPQ,ANXA7,APC,NLGN1,ST3GAL3,MIER1,BCO1,RUFY2,MSR1,CCDC88A,SCMH1,PDE8B,ASTN1,WDTC1,ILDR2,AHCYL1,NMNAT2,ARPP21,EMC1,TTLL9,DNER,NAP1L2,FXYD6,NCAM1,BCL2L2,NDUFA5,GPR162,DCAF5,SEPT3,FAM168A,OS9,ROBO3,GNG4,ANO4,PRUNE2,CACNA1E,LRIT2,PRLHR,PTBP2,EML4,VSTM2A,NUCB1,GRIA1,GRM3,TMEM25,LEFTY2,TMEM257,PAX6,CDC42,PADI2,PCDH9,PTGDR2,PDE3B,IGFN1,FNDC5,PFKFB3,CASC2,MS4A7,KIAA1549L,CPT1C,TJP2,FTO,SULT4A1,COL9A2,MFSD4A,PPP2R5C,PRKACB,KIAA1755,PLPP4,PLD5,SYTL2,PSMD13,JAKMIP2,CNIH3,COPS7A,CSDE1,KCNA6,KCNC1,SRGAP3,NTM,KCNJ10,NAV2,DLG3,WIPF2,SLC17A6,FAM66C,ATG16L1,SLC25A18,GNE,BSDC1,JMJD1C,VWA5A,SLC4A10,ELAVL4,RASGRP2,BAALC" MicroRNA hsa-miR-514:mirSVR_lowEffct hsa-miR-514:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-46 8.76E-43 1.39E-44 1.28E-43 114 1715 "ACER3,CNTNAP3,SYT9,ATAT1,CSMD3,KLRC4,PNMA8B,FCGR1A,SCNN1D,LRRC7,SEMA6A,BBOX1,UNC79,SLC30A10,SOX6,SGIP1,ANK3,PPFIA1,ITSN1,ANXA7,PKP4,PPM1E,ST3GAL3,AQP4,SLC8A3,CADPS,SCMH1,SLCO1A2,ASPH,TMEM108,SNAP25,DKK3,USP33,WDTC1,MYT1L,ZSWIM8,NAP1L2,NASP,NDUFA5,ERBIN,GFRA1,PHLDB1,ZNF638,KAZN,UNC5D,PRUNE2,GPM6A,ACSL6,LILRA1,VSTM2A,GRID1,RFFL,OMG,CRB1,MFSD2A,AIFM1,TMEM257,REPS2,PCDH8,CDH8,PTGDR2,HRH3,MAGI1,PDE1C,PDYN,BEST3,CASC2,MS4A7,TLX1,NOMO2,C11orf49,PRRX1,NXPH1,PNKD,CRLS1,SNCAIP,PPP3CB,RGS6,KCNT2,MICAL2,VCAN,RBPJ,PRKAB2,DOCK7,PRKCZ,MAPK8,PUM1,ECE2,FGFR1OP2,DPYSL5,CA10,PLPPR1,JAKMIP2,BDNF-AS,OLFM3,PTPRE,PTPRO,KCNMA1,RALGDS,C12orf4,DTNA,RTN4,RFX4,RGS7,INSYN2,ATL1,TTLL7,SFXN5,PIANP,SH3GLB1,ABI2,SLC4A10,RPE65,RCAN2" MicroRNA hsa-miR-127-5p:mirSVR_lowEffct hsa-miR-127-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-46 9.74E-43 1.52E-44 1.40E-43 118 1845 "TTYH1,SERPINA3,PRR5L,MAPT,CDHR1,MBP,RTN3,ACTN2,MEG3,LDLRAD3,F3,CLIP1,DSCAML1,GALNT13,ERMN,SNX30,KIAA1109,FGF1,PLA2G6,BCAR3,GOLGA7B,HPCAL4,TRIM46,PPFIA1,PPM1E,APC,ZNF365,RUFY2,LRRC55,PKNOX2,SLC8A3,NSG2,LGI3,NAXD,SMARCE1,TMEM108,USP33,CADM3,LHFPL4,ADAM15,NFASC,COLGALT2,BCL2L2,NCDN,GANAB,RND1,ARHGEF7,GLS,CASTOR3,LUZP2,DCLK2,MYRF,ANO4,CACNA1A,GPM6B,NEU4,ZEB1,GPR19,GRIA1,GRIA2,GRIN1,CYB561A3,LINC00839,TGFBR3,MFSD2A,ZDHHC22,DAAM2,REPS2,PCSK2,IGFN1,PRMT8,CASC2,GDAP1L1,PIK3CD,CNTN1,MEAF6,BEST1,PACSIN1,NSD2,NXPH1,ACBD5,CRMP1,MICAL2,ATRNL1,RIMS4,RBPJ,DZIP3,PRKCZ,CTNND2,MAPK10,KIAA0408,ZNF385B,PTCH1,CA10,BDNF-AS,PRDM2,OCIAD1,PTPRD,KCNA6,RABGAP1L,NAV2,DLG2,DNM2,RASGRF1,CAMK1G,NUP214,FAM135B,ARHGEF10L,SYT15,SEC61A2,PIANP,EFNA3,SH3GLB1,ABI2,YY1AP1,BSCL2,RPE65,EPB41" MicroRNA hsa-miR-641:mirSVR_highEffct hsa-miR-641:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-46 1.39E-42 2.14E-44 1.96E-43 121 1950 "SDE2,CSMD3,F3,CLIP1,KLHL32,RTN1,ADD3,GPR158,KIAA1109,ELMOD1,HPCAL4,MOBP,FOXG1,AMPH,SGIP1,PKP4,SH3GL2,APBA2,GPAM,MIER1,SLC14A1,CADPS,ASPH,SORCS3,SMARCE1,RCOR3,ATM,ATP1A2,ATP2B2,PALLD,USP33,SON,MYT1L,ZCCHC24,KIF1B,DNER,NPAS3,SPART,LMO3,NDUFA5,ERBIN,RGL1,ADHFE1,GLS,CAMTA1,CAMSAP2,ADGRL3,CNDP1,GPM6A,TCF7L2,ZEB1,PTBP2,EML4,CAMK2G,TMEM151B,OLR1,OMG,TGFBR3,MFSD2A,INA,TJP1,ZFP91,PCDH8,PCDH9,TPD52,TPM3,PCSK2,MAGI1,PDE3B,PDE4B,BEST3,CASC2,TMEFF2,CADM1,NRXN1,NMT2,CCSER2,DNAJC12,PLXNB3,CELF5,SLC25A27,SPATA6,CNRIP1,CHD1L,PPP2R5C,TENM4,PPP3CB,KCNT2,FEZ1,OSBPL3,PHACTR3,DZIP3,PKN2,USP54,MAPK10,EDRF1,BRINP3,TOX,GON4L,SYNC,DNAJC6,PTHLH,CNIH3,MAGI2,ZC3H11A,OLFM3,KCNA4,PLPPR4,KCNK1,KCNK2,PCDH15,ABI1,DSCAM,FAM13C,DTNA,RGS7,FAM135B,RPRD1A,VWA5A,LPAR6,BAALC" MicroRNA hsa-miR-1260b:mirSVR_lowEffct hsa-miR-1260b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.22E-46 1.74E-42 2.64E-44 2.42E-43 116 1791 "SDE2,LGR4,ECSIT,MDM4,RTN1,GALNT13,PNMA8B,TMEM156,ADORA3,FCGR1A,TOMM40L,LINC00461,FGF14,ASIC4,FHL1,UNC79,MOBP,PDZD4,SOX6,FOXM1,TRIM46,ASRGL1,PPM1E,GPAM,ST3GAL3,SLC1A6,RUFY2,SLC6A9,SLC14A1,DNAH17,ASPH,KBTBD12,TMEM108,ATP2B2,MEGF11,GABBR1,NMNAT2,JPH4,EMC1,IDI2-AS1,ALDH1L1,SMOC1,DCAF5,VAMP1,C1QC,DCLK2,CDK5R2,CACNB2,TMEM151B,NUMA1,GRIA1,GRIA2,CYB561A3,PTPN5,DAAM2,PADI2,DCLK1,LGI1,PDE1A,PDE2A,PRMT8,CHRM1,TUB,HNRNPK,ARHGAP22,GDAP1L1,ZFYVE9,CAMKV,UBTF,CELF5,PACSIN1,IFFO1,MFSD4A,PTPA,RGS6,MICAL2,OSBPL3,PLCH2,MAPK8,ECE2,MASP1,KIAA0513,SPIRE1,TOMM20,LRRTM3,ELMO1,CNIH3,PRDM2,STMN4,SRGAP3,RABGAP1L,TMCC2,KCNJ11,ARNT2,KCNMA1,PEX5,DLG2,HS3ST4,WIPF2,PID1,SLC17A6,PLEKHB2,FAM66C,ATG16L1,RAP1GAP,DTNA,PAK5,ABCC9,NUP214,RFX4,JMJD1C,ZNF248,GPR61,TMEM100,PRRT4,RASGRP2" MicroRNA hsa-miR-4289:mirSVR_lowEffct hsa-miR-4289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.39E-46 1.84E-42 2.74E-44 2.52E-43 114 1728 "EPS8,CDHR1,RTN3,EYA1,IL17D,MRVI1,ARID1A,CSMD3,NLGN4X,FCGR1A,CHST15,FGF1,LRRC7,BBOX1,MOBP,ERICH3,SGIP1,CCDC80,GPAM,DGKD,CACHD1,SYBU,ST3GAL3,BCAS1,SHTN1,MIER1,MSR1,LRRC55,CCDC88A,NSG2,SLCO1A2,SORCS3,EIF4G3,PHYHIPL,ATP2B2,WDTC1,MYT1L,B3GALT2,CAB39,ADAM15,KIF1B,CPLX2,LMO3,C11orf87,NELL1,RGL1,MLC1,GNAS,KLHL4,PRUNE2,GPM6B,ACSL6,DDR1,CACNB2,LILRA1,TCF7L2,ZEB1,TCF12,PTBP2,NUDT21,CAMK2G,CYB561A3,OLR1,INA,TLL2,C1orf94,PCDH8,LGI1,PDE1A,PRMT8,CASC2,DNAJC12,CNTN1,CELF5,BTF3L4,P2RY12,IFFO1,NSD2,FAT3,CP,POU3F2,MED1,CRLS1,PPP2R5C,SNCAIP,PPP3CB,KCNT2,MICAL2,OSBPL3,DOCK7,FMN2,PLPP4,MAPK10,ANKS1B,GON4L,ZNF385B,LRRTM3,DNAJC6,JAKMIP2,PRDM2,CSDE1,STMN4,PTPRD,PLPPR4,SRGAP3,KCNK2,DPP6,PAK5,RET,RFX4,FAM135B,ATL1,SLC4A10,UEVLD" MicroRNA hsa-miR-144:mirSVR_highEffct hsa-miR-144:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.66E-46 1.98E-42 2.91E-44 2.67E-43 122 1990 "RABEPK,EPS8,SDE2,LGR4,ARID1A,CSMD3,KLRC4,GRAMD1B,SLC44A5,GPR158,SLC30A10,FOXG1,ERICH3,SGIP1,ANK2,RASA3,ZCCHC17,CACHD1,BCAS1,MIER1,RUFY2,MSR1,ARHGAP5,CCDC88A,SHANK2,CADPS,ASCL1,SPHKAP,ASPH,SORCS3,SMARCE1,ATM,ATP2B2,PALLD,SON,SOX1,MYT1L,B3GALT2,ARPP21,GART,NPAS3,NDUFA5,ZNF302,RGL1,ARHGEF7,GLS,ZNF638,LUZP2,DDHD2,CAMSAP2,GPM6B,CACNB2,TCF7L2,ZEB1,TCF12,NUDT21,GRIA4,GRIK2,LINC00839,TJP1,TMEM257,ZFP91,TPD52,MAGI1,ZMYND8,CASC2,HNRNPK,JAM2,A2ML1,CCSER2,TJP2,DNAJC12,SLC25A27,PRRX1,SPATA6,ACBD5,POU3F2,KCNT2,OSBPL3,ATRNL1,NCAN,PHACTR3,RBPJ,PRKACB,FMN2,PKN2,USP54,PUM1,TOX,SYTL2,DPYSL5,SPIRE1,DNAJC6,ITGAV,PTHLH,CADM2,PRDM2,HP1BP3,RGMA,CEP170,ZC3H11A,KCNA4,C1orf109,KCNK2,SLC17A6,ABI1,RASGRF1,FAM13C,DBX2,DTNA,RTN4,PAK5,RET,RFX4,JMJD1C,RGS7,INSYN2,ZNF248,RPRD1A,RAVER2,SLC4A10,EPB41L2" MicroRNA hsa-miR-378c:mirSVR_lowEffct hsa-miR-378c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.35E-46 2.36E-42 3.41E-44 3.13E-43 119 1894 "SERPINA3,SYT9,SYNDIG1,MRVI1,ADAR,ADCY2,ADD3,ADORA1,CHST15,SNX32,FGR,SOX6,CDC42BPA,ITSN1,APBA2,NTNG1,MAGI3,CCDC80,ZCCHC17,PAAF1,SFMBT2,MSR1,LRRC55,PKNOX2,SLC8A2,SLC8A3,NSG2,SPHKAP,ASPH,KBTBD12,B3GAT1,NRG3,DKK3,WDTC1,ZCCHC24,CAB39,NMNAT2,IDI2-AS1,NFASC,NCAM1,SMOC1,GPR162,NELL1,ADHFE1,ZNF638,DCLK2,DDHD2,MMD2,ANO4,TBX15,GPM6B,TCF7L2,CLEC9A,TCF12,PTBP2,CAMK2A,CAMK2G,VXN,SYT6,NUMA1,AKNA,GRIK2,GPR88,FBXL16,DAAM2,TNFRSF1B,PCDH9,DCLK1,IGFN1,PIRT,LINC01102,GPR37L1,ANO5,CASC2,TUB,NLGN3,NMT2,CCSER2,TJP2,CNTN1,CELF5,MFSD4A,CHD1L,SF1,CRLS1,SNCAIP,TENM4,PPP3CB,KCNT2,ATRNL1,NCAN,EDRF1,WBP1L,ANKS1B,SYNC,SIRPA,KCNK1,KCNK2,NAV2,KCNN3,PEX5,DLG2,OLIG1,DNM2,SLC25A18,SUSD4,RASGRF1,L1CAM,NUP214,RFX5,FAM135B,VANGL2,RNF220,SSPN,SLC4A10,YY1AP1,EN2,EPB41,SEZ6" MicroRNA hsa-miR-1226:mirSVR_lowEffct hsa-miR-1226:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.59E-46 2.48E-42 3.55E-44 3.26E-43 119 1895 "SERPINA3,ABAT,PRR5L,MAP6,SYT9,ACTN2,WLS,MDM4,CSMD3,NDRG2,RTN1,CDC7,CHST15,TOMM40L,UNC79,ANK2,CNIH2,APBA2,MAGI3,DGKZ,SLITRK3,SORBS1,MIER1,RPH3A,PKNOX2,MT3,SLC14A1,ARFGAP1,ASPH,DKK3,WDTC1,B4GALNT1,ARPP21,IDI2-AS1,FXYD6,CLASP2,ERBIN,DCAF5,INKA2,RGL1,SEPT3,ARHGEF7,DCLK2,MMD2,CACNA1A,CACNA1E,CACNB2,HAP1,PTBP2,PCDHGA3,CECR2,NUCB1,AKNA,GRIA1,CRB1,SPX,MFSD2A,TMEM9,ZDHHC22,MAEL,CDC42,SEZ6L,TPD52,IGFN1,GPR37L1,LRTM2,CASC2,TLX1,GDAP1L1,UBTF,TJP2,FADS2,FTO,BTF3L4,PRRX1,FAT3,FAAP20,CHD1L,CRMP1,PTPA,SNCAIP,RGS6,FEZ1,OSBPL3,ECE2,NOS1AP,WBP1L,GON4L,PSMD13,PTCH1,PTHLH,CNIH3,PTPRD,KCNA6,PTPRO,SRGAP3,KCNJ10,TMCC2,KCNJ11,KCNK1,KCNMA1,PEX5,DLG2,WIPF2,TMEM255A,DNM2,FAM66C,DTNA,SLC6A15,ARHGEF10L,PHC2,ZNF248,SIDT2,GPR61,ABI2,SLC4A10,TMEM100,RASGRP2,SEZ6" MicroRNA hsa-miR-1259:mirSVR_highEffct hsa-miR-1259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.95E-46 2.68E-42 3.77E-44 3.46E-43 110 1609 "MEG3,EYA1,DSCAML1,KLRC4,ERMN,SLC44A5,KIAA1109,LRRC7,BBOX1,AMPH,ERICH3,SGIP1,ANK2,SH3GL2,PPM1E,MAGI3,GPAM,SLITRK3,JAKMIP3,AQP4,ZNF365,ARHGAP5,CADPS,SPHKAP,ASPH,RCOR3,SNAP25,ATP1A2,PHYHIPL,USP33,SOX5,KIF21B,AHCYL1,NPAS3,SPART,CLASP2,STOX1,ERBIN,KIRREL3,NEUROD1,GLS,DDHD2,CAMSAP2,ADGRL3,LILRA1,PTBP2,EML4,CECR2,DDR2,GPR88,OLR1,GUCY1A2,ZFP91,PAH,PAX6,HPS5,CDC42,PCDH9,PDE3B,HMGB1,SCRG1,CASC2,NEGR1,TJP2,PRRX1,P2RY12,NXPH1,ACBD5,POU3F2,ETNPPL,MED1,CRLS1,KCNT2,ATRNL1,VCAN,PRKACB,FMN2,CTNND1,PROX1,ZBTB16,ANKS1B,PLPPR5,SYNC,LRRTM3,SIRPA,PTHLH,CADM2,LRP8,CSDE1,KCNA2,PTPRD,PTPRE,C1orf109,RABGAP1L,PCDH15,DLG2,DLG3,PARP11,DPP6,RALGDS,C12orf4,FAM13C,SLC6A15,TTLL7,RPRD1A,ARHGAP12,CBLN2,SLC4A10,RCAN2,UEVLD" MicroRNA hsa-miR-508-5p:mirSVR_lowEffct hsa-miR-508-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.95E-46 3.77E-42 5.23E-44 4.80E-43 118 1870 "ACLY,SYT9,RCSD1,PAQR6,MEG3,ADGRV1,F3,RTN1,ADORA1,DRAXIN,GPR158,GOLGA7B,MOBP,RASA3,PI16,ITSN1,DOCK10,MAGI3,BCAN,NLGN1,JAKMIP3,BCAS1,PAAF1,ZNF365,SFMBT2,MSRA,ARFGAP2,NSG2,DACH2,ARFGAP1,DLL3,DDX25,RCOR3,ALDH4A1,ATM,WDTC1,TNIK,CADM3,ADAM15,NPAS3,NCAM1,ZNF302,GFAP,RCOR2,RGL1,GJB1,ADHFE1,CASTOR3,LUZP2,GNAS,CAMTA1,NODAL,UNC5D,MMD2,ADGRL3,TMEM136,DDR1,CACNB2,LILRA1,TCF7L2,TCF12,PTBP2,CAMK2G,CECR2,SYT6,USP2,MAEL,CDC42,CDH8,RBFOX2,SEZ6L,PDE3B,FNDC5,HMGB1,CCSER2,FTO,CELF5,BTF3L4,COL9A2,IFFO1,ATCAY,CP,POU3F2,CHD1L,RNF14,PTPA,ATRNL1,IGSF1,CTNND1,EDRF1,WBP1L,ANKS1B,PSMD13,CADM2,HP1BP3,CEP170,C1orf109,RABGAP1L,ARNT2,KCNK2,PCDH15,KCNMA1,PEX5,KCNQ2,PYGM,RAD52,FAM66C,DTNA,ZYG11B,USH1C,JMJD1C,FAM135B,INSYN2,PHC2,SSPN,RBM12,ABI2,RCAN2" MicroRNA hsa-miR-200b*:mirSVR_lowEffct hsa-miR-200b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.06E-46 3.82E-42 5.24E-44 4.81E-43 114 1741 "EPS8,LOC100128239,MAPT,SYT9,CSMD2,ARID1A,KCNIP2,CSMD3,CLIP1,KLRC4,CDC7,SORCS1,SLC44A5,LINC00461,FGF1,SEMA6A,ELMOD1,SOX6,AMPH,SFPQ,ANK3,PPFIA1,PPM1E,SESN3,APC,NTNG1,CCDC80,DGKZ,SLITRK3,NLGN1,AQP4,LRRC55,ARHGAP5,CCDC88A,ASCL1,SLCO1A2,SLIT1,ASPH,SNAP25,ATM,MYT1L,KIF21B,AHCYL1,NMNAT2,DNER,COLGALT2,BCL2L2,NELL1,SEPT3,NFIA,ARHGEF7,PCDH11X,GPM6A,GPM6B,CACNB2,PRLHR,ZEB1,TCF12,PTBP2,PCDHGA3,GRIA1,GRIA2,RFFL,GRIK2,TF,TLL2,TMEM257,PAX6,PCDH8,PCDH9,DCLK1,MAGI1,PDE3B,PDE4B,FNDC5,HERC2P3,HNRNPK,TMEFF2,CADM1,NEGR1,ANLN,FLRT1,FTO,MEAF6,SNCAIP,VCAN,PRKACB,PUM1,KLK6,WBP1L,SYTL2,ANKS1B,GON4L,ZNF385B,CADM2,CEP170,MAGI2,BLOC1S6,PTPRE,PCDH15,DLG2,DLG3,ATN1,GOPC,FAM13C,DBX2,DTNA,ATL1,SSPN,ABI2,ARHGAP12,CBLN2,RAVER2,BAALC" MicroRNA hsa-miR-505*:mirSVR_lowEffct hsa-miR-505*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.82E-46 5.32E-42 7.18E-44 6.59E-43 113 1715 "MAG,SERPINA3,LOC100128239,MAP6,RCSD1,PAQR6,RTKN,MDM4,F3,SLITRK1,GALNT13,WAC,SORCS1,GRAMD1B,FOXRED2,CHST15,FGF1,LRRC7,MOBP,MOG,SOX6,ANK3,ITSN1,APBA2,GPAM,PAAF1,SLC2A5,LRRC55,SLC8A3,SPHKAP,TAGLN3,ASTN1,C10orf105,MEGF11,GABBR1,WDTC1,SOX10,ZSWIM8,IDI2-AS1,NFASC,NCAM1,C11orf87,ALDH1L1,NCDN,SEPT3,NHLH1,DCLK2,KAZN,GNG4,BTRC,ATF7,PRLHR,GPR17,PTBP2,CAMK2A,VSTM2A,TF,LINC00839,MFSD2A,TMEM9,TLL2,CELF3,ZDHHC22,PADI2,TNS1,ZNF384,IGFN1,ZMYND8,ADGRG1,ASIC3,CASC2,TUB,CHRNB2,CCSER2,CNTN1,RGS6,ATRNL1,DZIP3,KIAA1755,CMTM5,PLPP4,PKN2,CTNND1,NRSN1,MAPK8,MAPK10,TOX,SIRPA,DNAJC6,ELMO1,PRDM2,PRTFDC1,COPS7A,MED24,KCNA6,PTPRO,KCNJ11,DLG2,KLRC3,RAD52,RALGDS,ATG16L1,ATN1,RASGRF1,RFX5,FAM135B,ZNF248,SEC61A2,SSPN,SIDT2,PIANP,C2orf80,UEVLD" MicroRNA hsa-miR-623:mirSVR_lowEffct hsa-miR-623:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.95E-46 5.39E-42 7.19E-44 6.59E-43 117 1844 "DPF1,TTYH1,SDE2,ABAT,CDHR1,RCSD1,SYNDIG1,ADGRV1,ARID1A,ADAR,WAC,ADORA3,SCN3A,KIAA1109,FGF14,SEMA6A,SLC30A10,HPCAL4,AMPH,ASRGL1,SGIP1,USP28,ITSN1,NTNG1,GPAM,SORBS1,API5,AQP4,MIER1,SLC1A7,SLC8A3,CCDC88A,SLC14A1,BRINP2,ASTN1,NRG3,SON,MYT1L,ENKUR,KIF1B,DNER,SPART,NFASC,NCAM1,C11orf87,BCL2L2,ERBIN,GFRA1,HEPN1,ADHFE1,RND1,SEPT3,VAMP1,ZNF638,LUZP2,CAMTA1,ANO4,CACNA1A,GPM6B,ZEB1,PTBP2,VXN,GUCY1A1,TMEM257,ZFP91,CDK11B,REPS2,PCDH9,IGFN1,PRMT8,ZMYND8,FNDC5,ANO5,TLX1,NLGN3,CADM1,CPT1C,A2ML1,OPALIN,C11orf49,SLC25A27,SLC36A4,NXPH1,SF1,CRLS1,MICAL2,ATRNL1,PRKAB2,DZIP3,FMN2,CTNND1,PROX1,MASP1,ZBTB16,TOX,ANKS1B,MED24,BLOC1S6,KCNA4,OCIAD1,KCNK2,DLG3,SLC25A18,FAM13C,BSDC1,FAM135B,INSYN2,ZNF248,EEF1A2,SEC61A2,RNF220,SSPN,SIDT2,EFNA3,FGFBP3,SLC4A10,RCAN2" MicroRNA hsa-miR-221*:mirSVR_lowEffct hsa-miR-221*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-45 6.09E-42 8.02E-44 7.36E-43 118 1879 "TTYH1,LOC100128239,ZFYVE27,SRARP,SYT9,ADGRV1,ATAT1,CSMD3,ADCY2,GRAMD1B,TESK2,KIAA1109,FGF1,HPCAL4,FOXM1,ERICH3,CDC42BPA,USP28,APC,SLITRK3,SYBU,NLGN1,ST3GAL3,USP16,ZNF365,RPH3A,SLC1A7,SLC2A5,RUFY2,SLC6A9,MT3,LGI3,SLN,ASTN1,EIF4G3,SON,ZSWIM8,B4GALNT1,ARPP21,ADAM15,FXYD6,NFASC,ADHFE1,SLCO1C1,SYT4,KAZN,GNAS,CAMTA1,GNG4,CDK5R2,BTRC,ADGRL3,PRUNE2,FAM69C,LILRA1,PCDHGA3,CECR2,NUMA1,GRIA1,GRIK3,CYB561A3,CRB1,TGFBR3,P2RX7,ZFP91,PCDH9,SEZ6L,CHI3L2,CASC2,HEPACAM,SEMA5B,A2ML1,CCSER2,PMP2,CABP1,BTF3L4,PRRX1,NSD2,ACBD5,MFSD4A,PLCH2,RBPJ,DZIP3,PLPP4,PRKCZ,USP54,IGSF1,CTNND1,ACY3,WBP1L,DPYSL5,LRRTM3,PTCH1,PLPPR1,JAKMIP2,PTHLH,ZC3H11A,KCNJ4,CCDC3,KCNK1,KCNMA1,KCNN3,WIPF2,FAM66C,RALGDS,GNE,L1CAM,CAMK1G,USH1C,JMJD1C,PHC2,SYT15,SSPN,ELAVL3,C2orf80,EPB41L2,RCAN2,BAALC" MicroRNA hsa-miR-1254:mirSVR_lowEffct hsa-miR-1254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-45 6.30E-42 8.18E-44 7.50E-43 121 1979 "SERPINA3,ZFYVE27,TMEM74,PAQR6,EXTL1,MEG3,MRVI1,KLHL32,ERMN,AMER2,CHST15,SNX32,PLA2G6,HPCAL4,MOBP,FOXG1,FOXM1,TRIM46,ANK1,RASA3,PI16,ITSN1,PKP4,APBB1,NTNG1,DGKD,ZCCHC17,JAKMIP3,SLC1A7,MADD,LRRC55,PKNOX2,SLC6A9,SLC8A2,SCMH1,LGI3,NAXD,SORCS3,ASTN1,WDTC1,CADM3,AHCYL1,ENKUR,JPH4,B4GALNT1,NEK6,IDI2-AS1,NCAM1,BCL2L2,SMOC1,GFAP,DCAF5,INKA2,PHLDB1,GANAB,SLCO1C1,ZNF638,SYT4,MYRF,MMD2,CNTN2,CACNA1E,DDR1,CACNB2,HAP1,NUDT21,PCDHGA3,GRID1,ADAMTS8,LINC00839,CRB1,TMEM25,TGFBR3,ZDHHC22,DAAM2,PADI2,RBFOX2,HRH3,LGI1,PRMT8,PIRT,CHGA,PFKFB3,CHI3L2,CHRM1,ARHGAP22,HEPACAM,NOMO2,CCSER2,CELF5,PRRX1,NSD2,PNKD,SNCAIP,MICAL2,OSBPL3,RBPJ,PRKAB2,KIAA1755,CMTM5,CTNND1,FAM131B,NOS1AP,MASP1,GON4L,SIRPA,STMN4,C1orf109,KCNJ10,TMCC2,SNX27,DLG2,SLC25A48,DNM2,FAM66C,RALGDS,RASGRF1,PAK5,PHC2,SIDT2,EPB41L1" MicroRNA hsa-miR-299-3p:mirSVR_lowEffct hsa-miR-299-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-45 6.45E-42 8.27E-44 7.59E-43 108 1562 "EPS8,ASIC1,SYT9,EYA1,MDM4,SLITRK1,GRAMD1B,ADORA1,SNX32,SCN4B,SEMA6A,HPCAL4,MOBP,ANK1,ANXA7,PKP4,NTNG1,ST3GAL3,JAKMIP3,SLC7A14,KIAA1614,SLC8A2,SLC8A3,CSPG5,SORCS3,ATP1A2,MEGF11,WDTC1,SOX1,B3GALT2,SOX10,NCAM1,STOX1,SMOC1,ACSBG1,GLS,VAMP1,ZNF638,GNAS,UNC5D,HAP1,NUMA1,GRIA2,GRIN1,CYB561A3,ATP13A2,OPCML,CRB1,TMEM25,LEFTY2,TMEM9,CELF3,CDC42,PADI2,CDH8,MAGI1,PDE1A,PRMT8,SCRG1,CHRM1,PLEKHB1,CASC2,CPT1C,SULT4A1,C11orf49,PRRX1,POU3F2,MED1,NKAIN4,FMN2,RAB39A,ARHGEF4,NRSN1,FAM131B,ECE2,MASP1,DPYSL5,PLPPR5,DNAJC6,ITGAV,BDNF-AS,ELMO1,PRDM2,OLFM3,KCNA6,PTPRO,SRGAP3,KCNJ9,KCNJ10,ARNT2,PCDH15,NAV2,DLG2,DLG3,HS3ST4,KLRC2,RAD52,PARP11,ATG16L1,ABI1,L1CAM,ABCC9,NUP214,SEC61A2,PIANP,VWA5A,ELAVL4,EPB41" MicroRNA hsa-miR-1244:mirSVR_lowEffct hsa-miR-1244:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-45 6.56E-42 8.30E-44 7.62E-43 112 1687 "ACER3,ACLY,CNTNAP3,SYT9,WLS,MDM4,SLC25A25,F3,ADCY2,ADD3,WAC,GRAMD1B,SLC44A5,TOMM40L,LRRTM4,KIAA1109,UNC79,SOX6,RASA3,USP28,ITSN1,GPAM,BCAN,TACC2,NLGN1,PAAF1,SLC1A2,SLC2A5,MSR1,SLC8A3,SLC14A1,CADPS,SLCO1A2,SMARCE1,CCDC181,NRG3,PALLD,DKK3,ZCCHC24,ILDR2,KIF1B,NAP1L2,LMO3,C11orf87,ADHFE1,NEUROD1,SEPT3,SLCO1C1,FAM168A,ACSBG1,NHLH1,PRUNE2,LILRA1,ZEB1,TCF12,PTBP2,EML4,VSTM2A,GRIA1,GRIK2,P2RX7,DCLK1,TPD52,TPM4,PDE3B,PRMT8,PDE4B,ANO5,PFKFB3,TUB,TMEFF2,JAM2,KIAA1549L,DNAJC12,FTO,BEST1,FAT3,NXPH1,RNF14,PPP2R5C,OSBPL3,ATRNL1,PHACTR3,PRKACB,DZIP3,EDRF1,ANKS1B,ITGAV,PRDM2,PTPRD,PTPRO,CCDC3,KCNK1,KCNMA1,NAV2,KIF2A,WIPF2,DNAH9,FAM13C,DTNA,PAK5,JMJD1C,INSYN2,ATL1,ARHGEF10L,SEC61A2,RNF220,RBM12,RERGL,VWA5A,ARHGAP12,CBLN2" MicroRNA hsa-miR-325-3p:TargetScan hsa-miR-325-3p TargetScan 1.93E-45 1.05E-41 1.31E-43 1.20E-42 113 1727 "EPS8,PRR5L,ACHE,EMID1,ACTN2,NDRG2,ADCY2,ADCYAP1R1,ERMN,ADORA3,AMER2,LCNL1,LRRTM4,LRRC7,C1QTNF4,GOLGA7B,MOBP,FOXM1,CDC42BPA,PPFIA1,ITSN1,CLSTN1,MT3,CADPS,CGREF1,GPR153,CAPRIN2,ALDH4A1,ATP1A2,ATP2B2,PALLD,GABBR1,SCN3B,NKX6-2,GART,RAP1GAP2,NASP,NFASC,NCAM1,C11orf87,GFRA1,NCDN,PHLDB1,GANAB,AJAP1,FAM168A,NFIA,MLC1,LUZP2,DCLK2,ROBO3,GNG4,DIRAS1,GPR26,NRGN,PTBP2,NUDT21,CAMK2A,CECR2,BRSK2,GRIK4,OPCML,PTPN5,GUCY1A2,KCNK10,REPS2,PC,PTGDR2,PRMT8,GPR37L1,HAPLN2,NTSR2,LRTM2,PFKFB3,HEPACAM,DLGAP3,GDAP1L1,KIAA1549L,NOMO2,NEGR1,HPR,NMT2,FTO,PMP2,PRRX1,IGSF1,PHYHIP,CA10,JAKMIP2,PMEPA1,KCNH1,KCNJ9,KCNJ11,CCDC3,ARNT2,NAV2,KCNN3,CALN1,RASGRF1,RTN4,FAM135B,EEF1A2,CACNG7,RBM12,RPRD1A,GPR61,FGFBP3,RAVER2,ROM1,C2orf80,PRRT4,EPB41,BAALC" MicroRNA hsa-miR-301a:mirSVR_lowEffct hsa-miR-301a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-45 1.06E-41 1.31E-43 1.20E-42 116 1824 "PRR5L,ASIC1,LGR4,LDLRAD3,CSMD2,FCGR1A,CHST15,SCN4B,LINC00461,LRRC7,BCAR3,MOBP,FOXG1,SOX6,SELL,PPFIA1,ITSN1,DOCK10,SLITRK3,SHTN1,ASCL1,SLCO1A2,RCOR3,KBTBD12,ATM,ATP1A2,DKK3,GABBR1,SON,B3GALT2,KIF21B,CAB39,JPH4,EMC1,NAP1L2,NPAS3,NCAM1,ADHFE1,AJAP1,MLC1,VAMP1,KAZN,TMEM136,ATF7,FAM69C,ZEB1,AZIN2,CAMK2G,CECR2,TMEM151B,VSTM2A,NUMA1,GRIA4,OLR1,OPCML,CRB1,USP2,GUCY1A1,CELF3,ZDHHC22,ZFP91,KCNK10,HPS5,CDC42,DCLK1,RBFOX2,MAGI1,PDE1A,PDE4B,SCRG1,ANO5,PFKFB3,MS4A7,NLGN3,VAV2,PMP2,SLC25A27,P2RY12,NSD2,FAT3,MED1,FEZ2,MICAL2,DZIP3,FMN2,SPIRE1,LRRTM3,CSDE1,MAGI2,KCNA4,PTPRD,PTPRE,AK5,KCNJ10,KCNK1,PCDH15,SNX27,DLG2,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,FAM13C,DTNA,RTN4,BSDC1,RFX5,JMJD1C,ZNF248,PIANP,SLC4A10,C2orf80,TMEM100,EPB41,UEVLD" MicroRNA hsa-miR-489:mirSVR_lowEffct hsa-miR-489:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.76E-45 1.49E-41 1.82E-43 1.67E-42 117 1863 "ACER3,MBP,SYT9,LGR4,SYNDIG1,MRVI1,ATAT1,LDLRAD3,MDM4,CSMD3,ADD3,SLC44A5,HOGA1,ASIC4,BCAR3,BBOX1,ELMOD1,MOG,SOX6,SFPQ,ITSN1,PPM1E,DOCK10,MIER1,SLC2A5,MSR1,SCMH1,ASCL1,SLCO1A2,ASPH,RCOR3,TMEM108,ATP1A2,MEGF11,USP33,GAD2,NMNAT2,NPAS3,NFASC,CLASP2,PHLDB1,PCDH11X,ZNF638,MMD2,LILRA1,TCF7L2,NUDT21,GRIA1,GRIA2,GRIA4,CRB1,MFSD2A,TMEM257,DAAM2,MAEL,TNFRSF1B,HPS5,TNS1,PCDH9,CDH8,CDH10,LGI1,PCSK2,FNDC5,GPR37L1,ASIC3,PLEKHB1,GDAP1L1,ZFYVE9,NRXN1,NEGR1,ANLN,SULT4A1,ATCAY,CP,ETNPPL,CHD1L,SF1,CRLS1,PPP3CB,VCAN,DOCK7,FMN2,RAB39A,PKN2,PUM1,FGFR1OP2,MASP1,BRINP3,TOX,ACY3,DPYSL5,DNAJC6,CADM2,RGMA,MAGI2,BLOC1S6,NTM,KCNK1,PCDH15,DLG3,GOPC,RASGRF1,BSDC1,RFX5,JMJD1C,FAM135B,INSYN2,PHC2,ZNF248,SEC61A2,SFXN5,RPRD1A,ABI2,VWA5A,ELAVL4,RPE65" MicroRNA hsa-miR-301b:mirSVR_highEffct hsa-miR-301b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.21E-45 3.36E-41 4.05E-43 3.71E-42 109 1621 "RABEPK,EPS8,TMEM74,CNTNAP3,ACTN2,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,GPR158,TESK2,SCN3A,FGF14,MOG,ERICH3,USP28,APBB1,APC,MAGI3,TACC2,SYBU,API5,ZNF365,MIER1,BCO1,RUFY2,CCDC88A,SHANK2,SLC14A1,NAXD,CAPRIN2,MTR,SNAP25,USP33,MYT1L,SOX5,B4GALNT1,TTLL9,TTC9B,SPART,CLASP2,NDUFA5,SMOC1,ERBIN,NEUROD1,GLS,SYT4,LUZP2,DDHD2,CAMTA1,CAMSAP2,PRUNE2,GPM6A,SYT6,GRIA2,GPR88,OMG,LINC00839,P2RX7,TNFRSF1B,TNS1,PCDH9,TPM3,PDE1C,PDE3B,DUSP26,ZFYVE9,CCSER2,ST8SIA5,PMP2,BTF3L4,ACBD5,POU3F2,RNF14,CRLS1,PPP3CB,CHD5,PRKACB,USP54,ARHGEF4,NRSN1,FGFR1OP2,PSD,SYNC,SIRPA,PLPPR1,PMEPA1,PTHLH,HP1BP3,LRP8,CEP170,CDH20,NTM,KCNN3,CAB39L,RAB5B,PID1,ATG16L1,C12orf4,ABCC9,RET,SLC39A12,RBM12,RPRD1A,ARHGAP12,RCAN2,BAALC" MicroRNA hsa-miR-890:mirSVR_lowEffct hsa-miR-890:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.97E-45 3.77E-41 4.44E-43 4.07E-42 109 1623 "MAPT,CNTNAP3,ADGRV1,LDLRAD3,WLS,KCNIP2,ADAR,DSCAML1,GALNT13,FCGR1A,SCN4B,SEMA6A,SLC30A10,HPCAL4,FOXM1,ANK1,PI16,PPFIA1,ITSN1,APC,MAGI3,TACC2,ST3GAL3,JAKMIP3,AQP4,LRRC55,ARHGAP5,NSG2,SORCS3,RCOR3,TMEM108,EIF4G3,MEGF11,SON,SOX5,B4GALNT1,ARPP21,EMC1,NEK6,C11orf87,BCL2L2,ZNF302,GPR162,INKA2,RHBDL3,DCLK2,CDK5R2,TBX15,WSCD1,CACNA1E,LRIT2,B4GALNT4,GPR19,HAP1,GRID1,CRB1,TMEM257,PAH,PAX6,PADI2,CDH10,ARHGAP19,MAGI1,PRMT8,CCSER2,CABP1,SLC36A4,NSD2,FAT3,NXPH1,ETNPPL,PTPA,OSBPL3,PLCH2,VCAN,NCAN,FMN2,RAB39A,PRKCZ,CTNND2,MAPK10,MASP1,TOX,WBP1L,HP1BP3,COPS7A,MAGI2,BLOC1S6,PTPRD,PLPPR4,PTPRO,PTPRZ1,RABGAP1L,PCDH15,DLG2,PID1,DNM2,RASGRF1,GNE,DBX2,L1CAM,SLC6A15,ZYG11B,NUP214,RFX4,VANGL2,SEC61A2,PIANP,SLC4A10" MicroRNA hsa-miR-514b-3p:mirSVR_lowEffct hsa-miR-514b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.97E-45 3.77E-41 4.44E-43 4.07E-42 109 1623 "CNTNAP3,SYT9,ATAT1,CSMD3,KLRC4,PNMA8B,SORCS1,FCGR1A,SCNN1D,LRRC7,SEMA6A,BBOX1,UNC79,SLC30A10,SOX6,SGIP1,ANK3,USP28,PPFIA1,ITSN1,ANXA7,PKP4,PPM1E,ST3GAL3,AQP4,CADPS,SCMH1,SLCO1A2,ASPH,TMEM108,SNAP25,DKK3,USP33,WDTC1,MYT1L,NAP1L2,NASP,NDUFA5,GFRA1,PHLDB1,ZNF638,CAMSAP2,UNC5D,PRUNE2,GPM6A,ACSL6,LILRA1,VSTM2A,GRID1,RFFL,OMG,CRB1,MFSD2A,TMEM257,MAEL,REPS2,PCDH8,CDH8,PTGDR2,HRH3,MAGI1,FNDC5,BEST3,CASC2,MS4A7,TLX1,NOMO2,C11orf49,PRRX1,NXPH1,PNKD,CRLS1,SNCAIP,PPP3CB,RGS6,KCNT2,MICAL2,VCAN,RBPJ,PRKAB2,DOCK7,PRKCZ,MAPK8,PUM1,ECE2,FGFR1OP2,DPYSL5,CA10,PLPPR1,JAKMIP2,OCIAD1,PTPRE,PTPRO,KCNMA1,RALGDS,C12orf4,DTNA,BSDC1,RFX4,RGS7,INSYN2,ATL1,TTLL7,SFXN5,SH3GLB1,ABI2,SLC4A10,RPE65,RCAN2" MicroRNA hsa-miR-935:mirSVR_lowEffct hsa-miR-935:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.33E-45 3.97E-41 4.61E-43 4.23E-42 111 1687 "TTYH1,TMEM74,MBP,CNTNAP3,LGR4,ACTN2,ARID1A,WLS,CLIP1,FCGR1A,TOMM40L,GPR158,KIAA1109,FGF14,BCAR3,SLC30A10,SOX6,ITSN1,SLITRK3,CACHD1,NLGN1,SHTN1,CLSTN1,DACH2,NAXD,CAPRIN2,SLN,MTR,ASTN1,B3GAT1,SNAP25,B3GALT2,ENKUR,ARPP21,KIF1B,DNER,FXYD6,NPAS3,GFAP,RND1,SLCO1C1,NFIA,ABCC8,SYT4,DDHD2,CNTN2,ADGRL3,ATF7,TCF12,VXN,RFFL,GRIK3,OMG,CRB1,P2RX7,ZFP91,TPM3,PDE3B,LINC01102,ZMYND8,SCRG1,TMPRSS5,ANO5,PFKFB3,CADM1,ZFYVE9,ANLN,MEAF6,SLC25A27,PRRX1,P2RY12,NSD2,FAT3,NXPH1,MFSD4A,SF1,RNF14,PPP3CB,ATRNL1,VCAN,PHACTR3,PRKACB,DOCK7,MAPK10,PUM1,FGFR1OP2,BRINP3,TOX,ANKS1B,TOMM20,PLPPR1,BDNF-AS,LRP8,CEP170,MAGI2,KCNA4,C1orf109,SRGAP3,AK5,KCNK1,DLG3,DPP6,C12orf4,FAM13C,JMJD1C,ZNF248,SEC61A2,FGFBP3,SLC4A10,RPE65,LRRC23" MicroRNA hsa-miR-301b:mirSVR_lowEffct hsa-miR-301b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.82E-45 4.23E-41 4.86E-43 4.46E-42 115 1817 "PRR5L,ASIC1,CDHR1,LGR4,LDLRAD3,CSMD2,WAC,FCGR1A,CHST15,SCN4B,LINC00461,LRRC7,BCAR3,MOBP,FOXG1,SELL,ITSN1,DOCK10,SLITRK3,SHTN1,ASCL1,SCG3,SLCO1A2,RCOR3,KBTBD12,ATP1A2,DKK3,SON,B3GALT2,KIF21B,CAB39,ZSWIM8,EMC1,NAP1L2,NCAM1,LMO3,ADHFE1,AJAP1,MLC1,VAMP1,KAZN,TMEM136,ATF7,ZEB1,AZIN2,CAMK2G,CECR2,TMEM151B,VSTM2A,NUMA1,GRIA4,OLR1,OPCML,CRB1,TMEM25,USP2,GUCY1A1,CELF3,ZFP91,KCNK10,DAAM2,REPS2,HPS5,CDC42,RBFOX2,MAGI1,PDE1A,PDE4B,SCRG1,ANO5,PFKFB3,CASC2,MS4A7,VAV2,SLC25A27,P2RY12,NSD2,FAT3,MED1,FEZ2,MICAL2,DOCK7,DZIP3,FMN2,SPIRE1,LRRTM3,CSDE1,MAGI2,KCNA4,PTPRD,PTPRE,KCNJ10,KCNK1,PCDH15,SNX27,DLG2,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,GNE,FAM13C,DTNA,RTN4,BSDC1,RFX5,JMJD1C,ZNF248,PIANP,SLC4A10,C2orf80,TMEM100,EPB41,UEVLD" MicroRNA hsa-miR-543:mirSVR_highEffct hsa-miR-543:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.03E-44 5.56E-41 6.32E-43 5.80E-42 111 1693 "EPS8,ACER3,CNTNAP3,ACTN2,ADGRV1,EYA1,MDM4,F3,CLIP1,RTN1,GALNT13,SLC44A5,KIAA1109,SLC30A10,MOBP,MOG,ASRGL1,DOCK10,MAGI3,TACC2,API5,RUFY2,MSR1,ASPH,SLN,SMARCE1,SNAP25,ATM,DKK3,SON,MYT1L,B3GALT2,CAB39,EMC1,NAP1L2,NPAS3,LMO3,RGL1,GLS,CASTOR3,PCDH11X,ZNF638,GNAS,UNC5D,GPM6A,CACNB2,TCF7L2,CAMK2G,TMEM151B,GRIK2,CRB1,PTPN5,MFSD2A,ZFP91,MAEL,HPS5,PCDH8,CDH10,PDE3B,ZMYND8,ANO5,NEGR1,NMT2,TJP2,SPATA6,NXPH1,CP,SF1,RNF14,PPP2R5C,PPP3CB,OSBPL3,ATRNL1,VCAN,DOCK7,PROX1,TOX,ANKS1B,GON4L,SIRPA,PTCH1,PLPPR1,PTHLH,CADM2,CSDE1,MAGI2,ZC3H11A,KCNA1,PTPRD,KCNA6,SMG7,SRGAP3,NTM,ARNT2,KCNK2,PCDH15,KCNMA1,PID1,TMEM255A,GOPC,DBX2,DTNA,PAK5,SLC39A12,SSPN,LMO1,ARHGAP12,ELAVL4,C2orf80,EN2,RPE65" MicroRNA hsa-miR-100*:mirSVR_lowEffct hsa-miR-100*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-44 6.50E-41 7.31E-43 6.70E-42 115 1825 "TTYH1,ACLY,CDHR1,EMID1,MBP,SYT9,MEG3,CSMD2,WLS,F3,KLHL32,ADCY2,KLRC4,ERMN,ADORA1,SCN3A,LRRTM4,KIAA1109,SLC30A10,FOXM1,TRIM46,ERICH3,SGIP1,RASA3,USP28,ITSN1,APBA2,APC,CCDC80,NLGN1,AQP4,ZNF365,SLC1A7,SLC14A1,DACH2,GPR153,CAPRIN2,ASPH,MTR,RCOR3,ATP1A2,NRG3,EIF4G3,MEGF11,USP33,SON,WDTC1,GAD2,ZSWIM8,NCAM1,COLGALT2,STOX1,ERBIN,AJAP1,SYT4,LUZP2,DCLK2,GNAS,CAMTA1,UNC5D,KLHL4,GPM6A,GPM6B,ZEB1,GPR19,VSTM2A,GRIK2,CYB561A3,LINC00839,ZDHHC22,PAX6,CDH10,TPD52,PDE1C,NTSR2,HNRNPK,DLGAP3,ZFYVE9,FTO,PMP2,BTF3L4,CP,CHD1L,CRLS1,TENM4,KCNT2,MICAL2,ATRNL1,NCAN,RBPJ,PRKACB,PKN2,PLD5,CTNND1,PUM1,TOX,TOMM20,LRRTM3,ITGAV,PLPPR1,PRTFDC1,RABGAP1L,PCDH15,DLG2,HS3ST4,PID1,C12orf4,GOPC,ZYG11B,JMJD1C,ATL1,VANGL2,SSPN,PLEKHO1,RPE65" MicroRNA hsa-miR-18a:mirSVR_lowEffct hsa-miR-18a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-44 7.12E-41 7.91E-43 7.25E-42 109 1634 "ASIC1,SYT9,F3,ADARB2,CLIP1,KLHL32,GALNT13,TUBB4A,FOXRED2,CHST15,SEMA6A,TRIM46,ERICH3,ANK2,PPFIA1,GPAM,JAKMIP3,CLSTN1,SLC2A5,LRRC55,ARHGAP5,CCDC88A,DACH2,SCG3,ARFGAP1,TAGLN3,NAXD,ASTN1,B3GAT1,IGSF9B,NRG3,EIF4G3,PALLD,WDTC1,ZCCHC24,ZSWIM8,NEK6,ADGRB2,FXYD6,NCAM1,CLASP2,ALDH1L1,NEUROD1,GLS,CAMSAP2,MYRF,KLHL4,GPM6A,CACNB2,LILRA1,TCF7L2,PTBP2,CAMK2G,NUMA1,GRIA4,GRIK3,OLR1,CRB1,TMEM25,TGFBR3,TJP1,NEURL1,PAX6,TNS1,PCDH9,PTGDR2,RBFOX2,TPM3,PIRT,HMGB1,SULT4A1,C11orf49,MFSD4A,CP,TENM4,RBPJ,PLPP4,IGSF1,CTNND2,KIAA0513,WBP1L,PLPPR5,BDNF-AS,PTHLH,CNIH3,RGMA,CSDE1,BLOC1S6,KCNA1,PTPRE,PLPPR4,PTPRO,PTPRZ1,SRGAP3,RAB5B,PID1,PARP11,ABI1,ABCC9,USH1C,RGS7,PHC2,TTLL7,PIANP,VWA5A,ARHGAP12,SLC4A10,PRRT4,BAALC" MicroRNA hsa-miR-200b:mirSVR_highEffct hsa-miR-200b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.38E-44 7.49E-41 8.23E-43 7.55E-42 114 1795 "EPS8,SDE2,ABAT,ACER3,ACHE,LDLRAD3,ARID1A,CSMD3,CLIP1,SLITRK1,ADD3,ERMN,AMER2,NLGN4X,GPR158,TESK2,FHL1,ELMOD1,FOXG1,ERICH3,SGIP1,ANK2,PPFIA1,ITSN1,PKP4,ZNF365,SLC8A3,SLC14A1,SLIT1,CAPRIN2,ASPH,SORCS3,SMARCE1,SNAP25,FYN,SOX1,ZCCHC24,KIF21B,CAB39,ENKUR,ARPP21,KIF1B,GART,NAP1L2,SPART,C11orf87,CLASP2,ZNF302,RGL1,PHLDB1,GLS,VAMP1,CAMSAP2,MMD2,ADGRL3,TMEM136,GPM6A,CACNB2,ZEB1,PTBP2,EML4,CECR2,AKNA,GRIA2,GRIA4,TGFBR3,TLL2,HPS5,PCDH8,ARHGAP19,PCSK2,HMGB1,HNRNPK,TMEFF2,SERPINE2,NRXN1,NEGR1,ANLN,A2ML1,TJP2,SLC25A27,BTF3L4,COL9A2,NXPH1,CSF3R,FEZ2,PHACTR3,PRKACB,IGSF1,CTNND2,WBP1L,SYNC,LRRTM3,SIRPA,PTCH1,PLPPR1,BDNF-AS,PTHLH,BLOC1S6,OCIAD1,PTPRD,PLPPR4,PTPRZ1,DNAH9,FAM13C,DTNA,PAK5,ABCC9,RET,ZNF248,SEC61A2,RPRD1A,RAVER2,SLC4A10" MicroRNA hsa-miR-573:mirSVR_highEffct hsa-miR-573:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-44 9.10E-41 9.89E-43 9.08E-42 97 1276 "LOC100128239,SYT9,RTN3,WLS,CSMD3,CDC7,ADORA3,SLC44A5,LRRTM4,FGF14,AMPH,ANK2,ITSN1,PKP4,SH3GL2,SESN3,APC,SLITRK3,SYBU,NLGN1,AQP4,RUFY2,MSR1,ARHGAP5,ASPH,SMARCE1,SNAP25,PHYHIPL,DKK3,B3GALT2,SOX5,B4GALNT1,ARPP21,ADGRB2,NPAS3,NASP,ERBIN,GFRA1,NELL1,ADHFE1,AJAP1,ANO4,GPM6B,ACSL6,CACNB2,NUMA1,GRIA4,GRIK2,TGFBR3,GUCY1A1,TLL2,MAEL,TNR,PCDH9,CDH10,PCSK2,PDE3B,HMGB1,A2ML1,CRLS1,PTPA,KCNT2,MICAL2,VCAN,NCAN,PKN2,PRKCZ,IGSF1,CTNND1,NRSN1,PROX1,TOX,ANKS1B,CA10,PTHLH,LRP8,CEP170,OCIAD1,PTPRD,PTPRE,KCNC1,PTPRO,PCDH15,CAB39L,KLRC2,PID1,SLC25A48,FAM13C,SLC6A15,RGR,JMJD1C,FAM135B,ZNF248,SYT15,SEC61A2,RBM12,ABI2" MicroRNA hsa-miR-31:mirSVR_lowEffct hsa-miR-31:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-44 1.06E-40 1.14E-42 1.05E-41 113 1769 "MAP6,ACHE,CDHR1,EMID1,TMEM74,LGR4,SYNDIG1,CSMD2,WLS,CSMD3,WAC,FABP7,LINC00461,UNC79,PDZD4,SFPQ,ERICH3,PI16,SH3GL2,MADD,LRRC55,SLC6A9,DACH2,CGREF1,SPHKAP,CAPRIN2,ASPH,SLN,SORCS3,NRG3,PALLD,SCN3B,WDTC1,SALL3,NEK6,SPART,NFASC,RGL1,ADHFE1,SEPT3,MLC1,RHBDL3,PCDH11X,C1QC,BTRC,GPM6B,CACNA1E,CACNB2,NUDT21,CAMK2G,TMEM151B,VXN,SYT6,VSTM2A,GRIA2,GRIA4,TGFBR3,USP2,TJP1,ATG4C,CD81,CDC42,PADI2,PCDH8,PCDH9,DCLK1,RBFOX2,TPM4,CASC2,DLGAP3,KIAA1549L,CAMKV,SEMA5B,ANLN,OPALIN,FADS2,BTF3L4,PRRX1,PPP2R5C,PPP3CB,ATRNL1,CHD5,PRKAB2,DZIP3,PRKCG,PLPP4,MAPK10,RIMS3,DPYSL5,PSMD13,PLPPR1,PRDM2,COPS7A,CSDE1,MAGI2,KCNA2,OLFM3,PTPRE,SRGAP3,NTM,KCNN3,CAB39L,ATG16L1,RASGRF1,RTN4,SLC6A15,ZYG11B,INSYN2,SYT15,SSPN,SIDT2,FGFBP3,EPB41" MicroRNA hsa-miR-148a*:mirSVR_lowEffct hsa-miR-148a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.05E-44 1.11E-40 1.18E-42 1.09E-41 119 1968 "ABAT,ACER3,RBM10,RTN3,ADGRV1,EYA1,LDLRAD3,CSMD3,F3,RTN1,DSCAML1,GALNT13,FOXRED2,FCGR1A,CHST15,TESK2,LRRTM4,FHL1,GOLGA7B,SLC30A10,FOXG1,MOG,SOX6,SFPQ,ANK2,PPFIA1,NTNG1,SORBS1,CACHD1,AQP4,PKNOX2,SHANK2,SLC14A1,SCG3,TMEM108,SNAP25,ATM,CCDC181,DKK3,SCN3B,MYT1L,ZCCHC24,NMNAT2,FXYD6,NFASC,ERBIN,DCAF5,SLCO1C1,GLS,ZNF638,GNAS,KLHL4,CACNA1A,ACSL6,PTBP2,NUDT21,TMEM151B,DDR2,GRIA2,GRIK2,LEFTY2,GUCY1A1,TJP1,TMEM257,PAH,TNS1,TPD52,PDE3B,CHGA,CASC2,HERC2P3,HNRNPK,KIAA1549L,SEMA5B,PIK3CD,TJP2,CNTN1,FAT3,CRLS1,KCNT2,FEZ1,MICAL2,RBPJ,PRKAB2,FMN2,KIAA0408,BRINP3,WBP1L,SYNC,LRRTM3,PTCH1,JAKMIP2,CADM2,CEP170,MAGI2,STMN4,KCNA4,KCNC1,SV2A,KCNMA1,KIF2A,HS3ST4,OLIG1,RAB5B,C12orf4,DTNA,ABCC9,RFX4,JMJD1C,RGS7,SSPN,SH3GLB1,LMO1,ABI2,LPAR6,C2orf80,EPB41,LRRC23,BAALC" MicroRNA hsa-miR-548c-3p:PITA hsa-miR-548c-3p:PITA_TOP PITA 2.44E-44 1.32E-40 1.39E-42 1.28E-41 94 1196 "SDE2,ACLY,EYA1,ARID1A,CLIP1,ADD3,TESK2,SCN3A,PDZD4,SOX6,ANK1,ANK3,PKP4,SH3GL2,NTNG1,MAGI3,DGKZ,GPAM,SLITRK3,SORBS1,NLGN1,PKNOX2,ARHGAP5,ASTN1,SMARCE1,RCOR3,SNAP25,ATP2B2,MEGF11,SOX5,ZCCHC24,CAB39,AHCYL1,SALL3,SPART,LMO3,ERBIN,FAM168A,NFIA,PCDH11X,ZNF638,NKX2-2,CAMSAP2,ADGRL3,WWC1,GPM6A,TCF12,PTBP2,PSD3,GRIA2,TJP1,CELF3,ZFP91,CDC42,C1orf94,PCSK2,LRTM2,HNRNPK,NLGN3,NEGR1,CNTN1,CRMP1,TENM4,CHD5,PRKAB2,CTNND1,CTNND2,MAPK8,KIAA0408,FGFR1OP2,LRRTM3,CNIH3,HP1BP3,CSDE1,KCNA1,PTPRD,PTPRZ1,KCNMA1,PEX5,DLG2,TMEM255A,DSCAM,RET,INSYN2,VANGL2,RBM12,SH3GLB1,ARHGAP12,EN2,TMEM100,EPB41,EPB41L1,EPB41L2,RCAN2" MicroRNA hsa-miR-1202:mirSVR_lowEffct hsa-miR-1202:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.31E-44 1.80E-40 1.87E-42 1.72E-41 111 1714 "DPF1,SERPINA3,ZFYVE27,MAPT,ACLY,SYT9,MEG3,CSMD3,ADD3,TESK2,SCN4B,LRRTM4,LINC00461,KIAA1109,PLA2G6,PDZD4,ERICH3,ANK1,ANK2,ANK3,CNIH2,BCAS1,SHTN1,SFMBT2,MSR1,ARHGAP5,DACH2,ASPH,B3GAT1,TMEM108,ALDH4A1,MEGF11,DKK3,WDTC1,KIF21B,ZSWIM8,NMNAT2,ENKUR,NFASC,NCAM1,CLASP2,GFAP,RGL1,GLS,CASTOR3,PCDH11X,DCLK2,KAZN,ADGRL3,ANO4,PRUNE2,ZEB1,DIRAS1,NUDT21,CECR2,BRSK2,RFFL,ATP13A2,TMEM25,ZDHHC22,ZFP91,PTGDR2,RBFOX2,PDE3B,FNDC5,CASC2,TLX1,DUSP26,SEMA5B,UBTF,TJP2,ST8SIA5,PLXNB3,MEAF6,PACSIN1,MFSD4A,POU3F2,NKAIN4,MICAL2,DOCK7,DZIP3,SDC3,PRKCZ,USP54,NRSN1,PUM1,MASP1,ZBTB16,SPIRE1,PTAFR,ELMO1,PRDM2,CSDE1,MED24,KCNA6,PTPRE,PLPPR4,C1orf109,KCNK1,NKAIN1,OLIG1,SLC25A48,RAD52,C12orf4,DTNA,PAK5,BSDC1,NUP214,PHC2,SYT15,RCAN2" MicroRNA hsa-miR-34a*:mirSVR_lowEffct hsa-miR-34a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.48E-44 1.88E-40 1.94E-42 1.78E-41 115 1845 "RPL38,ZFYVE27,MAPT,SYT9,DUSP27,RCSD1,ACTN2,MDM4,ADARB2,WAC,SORCS1,TOMM40L,HOGA1,LRRTM4,UNC79,SLC30A10,SOX6,PPFIA1,MAGI3,SYBU,ST3GAL3,BCAS1,PKNOX2,ARHGAP5,NSG2,DACH2,SCG3,SLCO1A2,SPHKAP,SLIT1,SNAP25,FYN,PHYHIPL,GABBR1,SON,WDTC1,SOX1,MYT1L,SOX5,ILDR2,ZSWIM8,EMC1,TTLL9,DNER,C11orf87,GFRA1,AJAP1,ARHGEF7,PCDH11X,ZNF638,BTRC,TMEM136,TBX15,PRUNE2,ACSL6,VWC2,TCF7L2,PCDHGA3,CRB1,PTPN5,AIFM1,TLL2,TMEM257,HPS5,PCDH9,RBFOX2,CIART,PDYN,CASC2,SEMA5B,NEGR1,PLXNB3,CNTN1,MEAF6,CELF5,PRRX1,IFFO1,NXPH1,ACBD5,ETNPPL,CHD1L,CRLS1,KCNT2,OSBPL3,IGSF1,NRSN1,PUM1,HES5,LRRTM3,PSMD13,ITGAV,CA10,PLPPR1,PRDM2,CEP170,CSDE1,KCNA1,SV2A,SRGAP3,NTM,TMCC2,PCDH15,DLG2,DSCAM,RASGRF1,JMJD1C,ATL1,SEC61A2,ABI2,FGFBP3,SLC4A10,ROM1,RPE65,TMEM100,BAALC" MicroRNA hsa-miR-625:mirSVR_highEffct hsa-miR-625:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.14E-44 2.24E-40 2.29E-42 2.10E-41 87 1012 "ACHE,ACLY,ACTN2,IL17D,ATAT1,ARID1A,KCNIP2,CSMD3,NDRG2,RTN1,DSCAML1,GRAMD1B,LINC00461,FGF1,SEMA6A,ANK2,PPFIA1,ITSN1,PPM1E,ST3GAL3,ZNF365,SLC8A3,SCG3,ASPH,GABBR1,GAD2,JPH4,NDUFA5,INKA2,RGL1,GANAB,CASTOR3,PCDH11X,KAZN,ADGRL3,DDR1,TCF7L2,TCF12,PCDHGA3,GRIA4,GRIK2,GRM3,LEFTY2,TGFBR3,INA,DCLK1,PTGDR2,ZMYND8,ACOT7,PLEKHB1,HNRNPK,SERPINE2,CADM1,ZFYVE9,FLRT1,CNTN1,BEST1,BTF3L4,POU3F2,CRMP1,SNCAIP,KCNT2,OSBPL3,USP54,CTNND1,CTNND2,EDRF1,MASP1,PLPPR5,DNAJC6,CA10,CADM2,CEP170,OCIAD1,PTPRO,CCDC3,KCNMA1,PEX5,RAB5B,FAM66C,ATG16L1,SUSD4,DTNA,BSDC1,INSYN2,PIANP,RCAN2" MicroRNA hsa-miR-3136:mirSVR_lowEffct hsa-miR-3136:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.35E-44 2.35E-40 2.38E-42 2.18E-41 109 1655 "MAPT,ACTN2,MRVI1,CSMD2,ARID1A,CSMD3,KLHL32,ERMN,FOXRED2,PLA2G6,LRRC7,SGIP1,CDC42BPA,PPM1E,NTNG1,SLITRK3,ST3GAL3,ZNF365,ARFGAP2,DACH2,RCOR3,TMEM108,ATP2B2,GABBR1,B3GALT2,CAB39,ILDR2,ENKUR,TTLL9,ADAM15,KIF1B,CPLX2,NFASC,ALDH1L1,ACSBG1,ARHGEF7,VAMP1,CASTOR3,LUZP2,GNAS,PSRC1,ADGRL3,KLHL4,ATF7,ZEB1,TCF12,DIRAS1,PTBP2,NUDT21,GRIK2,GRM3,OPCML,KCNK10,MAEL,IGSF21,CDH8,DCLK1,TPM4,MAGI1,PDE3B,ZMYND8,LRTM2,HNRNPK,ANLN,A2ML1,CCSER2,OPALIN,FTO,CCDC136,VAV2,ACBD5,MFSD4A,POU3F2,CRLS1,SNCAIP,PRKACB,PRKCZ,HES5,KIAA0408,FGFR1OP2,SPIRE1,LRRTM3,DNAJC6,ELMO1,CEP170,KCNA4,PTPRD,KCNA6,PTPRE,KCNC1,PTPRZ1,AK5,KCNK1,KCNK2,CAB39L,PID1,PARP11,FAM57B,SLC25A18,RASGRF1,GNE,SLC6A15,JMJD1C,ZNF248,ARHGAP12,RAVER2,SLC4A10,PLEKHO1,TMEM100" MicroRNA hsa-miR-654-3p:mirSVR_lowEffct hsa-miR-654-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.14E-44 3.33E-40 3.32E-42 3.04E-41 116 1889 "ZFYVE27,SYT9,EXTL1,LDLRAD3,MDM4,CLIP1,DSCAML1,SORCS1,CHST15,KIAA1109,FGF14,SLC30A10,HPCAL4,PPFIA1,ITSN1,SESN3,APC,CCDC80,NLGN1,SHTN1,ZNF365,SLC2A5,RUFY2,PKNOX2,SLC8A2,MT3,RCOR3,B3GAT1,ATM,PHYHIPL,MEGF11,SON,SOX5,CADM3,SALL3,NEK6,CPLX2,NFASC,C11orf87,ZNF302,SLCO1C1,SYT4,LUZP2,CAMTA1,MMD2,BTRC,ANO4,ATF7,ACSL6,EML4,VXN,GRIA4,GPR88,OPCML,CRB1,INA,P2RX7,CDH8,PCSK2,MAGI1,TUB,NRXN2,CCSER2,OPALIN,TJP2,FTO,PRRX1,FAT3,NXPH1,MFSD4A,MED1,SF1,SNCAIP,OSBPL3,PHACTR3,PRKAB2,PRKACB,DOCK7,FMN2,KIAA1755,RAB39A,IGSF1,NRSN1,MAPK10,ECE2,FGFR1OP2,MASP1,BRINP3,ZBTB16,TOX,SYTL2,ANKS1B,GON4L,TOMM20,PMEPA1,PRDM2,PRTFDC1,LRP8,PTPRD,C1orf109,CAB39L,KIF2A,FAM66C,GOPC,GNE,L1CAM,BSDC1,ABCC9,RFX4,JMJD1C,PHC2,VANGL2,SYT15,RNF220,RPRD1A,ELAVL3" MicroRNA hsa-miR-216b:mirSVR_lowEffct hsa-miR-216b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.19E-44 3.35E-40 3.32E-42 3.04E-41 114 1823 "RABEPK,SERPINA3,SDE2,MAP6,ARID1A,SORCS1,GRAMD1B,SNX30,NLGN4X,HOGA1,FGF1,UNC79,SLC30A10,PDZD4,AMPH,ERICH3,CDC42BPA,NTNG1,MAGI3,GPAM,SLITRK3,SORBS1,STK32C,SHTN1,DACH2,SLCO1A2,LGI3,CAPRIN2,SMARCE1,MEGF11,KIF1B,NCAM1,STOX1,ERBIN,RGL1,NEUROD1,NFIA,GLS,VAMP1,PCDH11X,POPDC3,CAMTA1,CAMSAP2,UNC5D,PSRC1,ADGRL3,KLHL4,LILRA1,PRLHR,DIRAS1,PTBP2,EML4,VSTM2A,GRIA1,GRIA2,GRIA4,GPR88,OPCML,LINC00839,CRB1,P2RX7,ZFP91,PCDH9,TPM4,MAGI1,PDE3B,IGFN1,PDE4B,GPR37L1,BEST3,HMGB1,PFKFB3,TMEFF2,CADM1,CCSER2,FAM181B,CELF5,CHD1L,FEZ2,ATRNL1,CHD5,PRKAB2,NOS1AP,TOX,RIMS3,DPYSL5,ANKS1B,SPIRE1,TOMM20,ZNF385B,PTHLH,ELMO1,HP1BP3,CEP170,MAGI2,ZC3H11A,KCNK1,KCNK2,PCDH15,SLC17A6,ABI1,DTNA,RTN4,ABCC9,ZYG11B,NUP214,RET,RGS10,FAM135B,SSPN,FGFBP3,CBLN2,OLIG2,EPB41" MicroRNA hsa-miR-485-3p:mirSVR_lowEffct hsa-miR-485-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.65E-44 4.14E-40 4.06E-42 3.73E-41 114 1827 "MBP,MEG3,CSMD3,CLIP1,RTN1,ADD3,GRAMD1B,SLC44A5,GPR158,ELMOD1,HPCAL4,SOX6,CDC42BPA,CNIH2,PPFIA1,PKP4,APBA2,DOCK10,APC,MAGI3,DGKD,BCAN,TACC2,SORBS1,NLGN1,ZNF365,CCDC88A,DACH2,CADPS,NAXD,NRG3,DKK3,SCN3B,SON,SOX1,TNIK,SOX5,NEK6,CPLX2,NPAS3,LMO3,NDUFA5,DCAF5,RGL1,NFIA,ARHGEF7,GLS,SYT4,DDHD2,ROBO3,UNC5D,TMEM136,ANO4,GPM6B,ATF7,PTBP2,CAMK2G,VSTM2A,GRIK3,OMG,MFSD2A,P2RX7,PAH,CD81,MAEL,TNS1,C1orf94,CDH8,PDE3B,PDE4B,ADGRG1,ANO5,PFKFB3,TUB,HNRNPK,ANLN,SULT4A1,CNTN1,P2RY12,ACBD5,MFSD4A,CP,PTPA,SNCAIP,PPP3CB,FEZ2,RBPJ,FMN2,CTNND2,NRSN1,MAPK10,KIAA0513,SYTL2,PLPPR5,BDNF-AS,ELMO1,LRP8,PTPRE,KCNK1,PCDH15,DLG2,SLC17A6,PLEKHB2,GOPC,DTNA,RTN4,RET,PHC2,ZNF248,TTLL7,RERGL,ABI2,ARHGAP12,LRRC23" MicroRNA hsa-miR-3162:mirSVR_lowEffct hsa-miR-3162:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-43 6.90E-40 6.70E-42 6.14E-41 105 1548 "LOC100128239,PRR5L,ZFYVE27,ASIC1,MBP,ADAR,ADARB2,GALNT13,CHST15,TOMM40L,ELMOD1,TRIM46,ERICH3,SGIP1,CDC42BPA,ITSN1,SORBS1,JAKMIP3,BCAS1,LRRC55,ARFGAP2,SLC8A3,CCDC88A,SMARCE1,ATM,ATP1A2,SCN3B,MYT1L,KIF21B,SOX10,ZSWIM8,NMNAT2,NPAS3,RAP1GAP2,NFASC,NDUFA5,STOX1,SEPT3,MLC1,GLS,RHBDL3,SYT4,GNG4,CNDP1,ATF7,DDR2,VSTM2A,NUMA1,GRIA1,OPCML,TGFBR3,USP2,FBXL16,INA,GUCY1A2,TJP1,CDH8,CDH10,PCSK2,ZNF384,PRMT8,LRTM2,ASIC3,PLEKHB1,CASC2,HEPACAM,BTF3L4,SPATA6,IFFO1,CRLS1,PTPA,MICAL2,OSBPL3,VCAN,PRKACB,RAB39A,CTNND2,NOS1AP,PHYHIP,BDNF-AS,ELMO1,CEP170,MAGI2,OCIAD1,KCNA6,PTPRE,KCNK1,KCNK2,NAV2,DLG2,DLG3,RAB5B,DPP6,GNE,DBX2,ZYG11B,INSYN2,TTLL7,VANGL2,SEC61A2,SLC39A12,PIANP,VWA5A,SLC4A10,EPB41" MicroRNA hsa-miR-424:mirSVR_highEffct hsa-miR-424:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.60E-43 8.64E-40 8.31E-42 7.62E-41 103 1490 "CDHR1,RTN3,SYNDIG1,EYA1,CSMD2,KCNIP2,GALNT13,TMEM156,SCN3A,LRRTM4,DISP3,LRRC7,ASIC4,FHL1,ELMOD1,SLC30A10,SELL,ANK2,SH3GL2,PPM1E,GPAM,NLGN1,ST3GAL3,BCAS1,ZNF365,CCDC88A,CSPG5,SLN,RCOR3,SNAP25,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,DNER,NPAS3,NFASC,BCL2L2,NELL1,ACSBG1,GLS,SYT4,KAZN,GNAS,UNC5D,BTRC,WWC1,PTBP2,VXN,VSTM2A,GRIA2,OMG,CRB1,TGFBR3,CDC42,PCDH9,BEST3,HMGB1,CADM1,NRXN1,OPALIN,PRRX1,NXPH1,ACBD5,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,FEZ1,MICAL2,RBPJ,DOCK7,MASP1,SYTL2,ANKS1B,JAKMIP2,PMEPA1,PTHLH,PRDM2,CSDE1,PTPRD,NTM,KCNJ11,KCNK1,KCNK2,PEX5,KIF2A,DNAH9,PID1,TMEM255A,RET,RFX4,SEC61A2,SIDT2,RBM12,ABI2,ARHGAP12,EN2,TMEM100,RCAN2" MicroRNA hsa-miR-1272:mirSVR_highEffct hsa-miR-1272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-43 9.63E-40 9.17E-42 8.41E-41 106 1585 "ABAT,ACER3,EYA1,ATAT1,KLRC4,ADD3,AMER2,GPR158,SCN3A,HPCAL4,ERICH3,ANK2,USP28,SH3GL2,APC,NTNG1,SLITRK3,AQP4,SLC1A6,RPH3A,MSR1,CCDC88A,PDE8B,SLCO1A2,ASPH,TMEM108,ATM,NRG3,PALLD,USP33,KIF1B,NAP1L2,NPAS3,CLASP2,NDUFA5,STOX1,RND1,SYT4,POPDC3,ANO4,PRUNE2,ACSL6,CACNB2,TCF7L2,TCF12,EML4,VXN,GRIA4,CRB1,INA,CDC42,PCDH9,CDH8,CDH10,LGI1,TPD52,MAGI1,PDE1C,PDE3B,BEST3,HNRNPK,TMEFF2,GDAP1L1,NEGR1,NMT2,NSD2,CP,MED1,PPP2R5C,PPP3CB,KCNT2,VCAN,NCAN,PRKACB,IGSF1,CTNND2,NRSN1,MAPK8,PROX1,WBP1L,DNAJC6,ITGAV,PTHLH,HP1BP3,LRP8,STMN4,OLFM3,OCIAD1,PTPRD,C1orf109,KCNK2,PCDH15,SLC25A48,RALGDS,FAM13C,RTN4,PAK5,ABCC9,RET,RLBP1,SEC61A2,SSPN,ABI2,SLC4A10,LRRC23,BAALC" MicroRNA hsa-miR-200c:mirSVR_highEffct hsa-miR-200c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.97E-43 1.07E-39 1.01E-41 9.24E-41 113 1812 "EPS8,ABAT,ACER3,ACHE,LDLRAD3,ARID1A,CSMD3,CLIP1,SLITRK1,ADD3,ERMN,AMER2,NLGN4X,GPR158,TESK2,FHL1,FOXG1,ERICH3,SGIP1,PPFIA1,ITSN1,PKP4,ZNF365,SLC8A3,SLC14A1,SLIT1,CAPRIN2,ASPH,SORCS3,SMARCE1,SNAP25,FYN,SOX1,ZCCHC24,KIF21B,CAB39,ENKUR,ARPP21,KIF1B,GART,NAP1L2,SPART,C11orf87,CLASP2,ZNF302,RGL1,PHLDB1,GLS,VAMP1,CAMSAP2,MMD2,ADGRL3,TMEM136,GPM6A,CACNB2,ZEB1,PTBP2,CECR2,AKNA,GRIA2,GRIA4,TGFBR3,TLL2,HPS5,PCDH8,ARHGAP19,TPD52,PCSK2,PDE4B,HMGB1,HNRNPK,TMEFF2,NRXN1,NEGR1,ANLN,A2ML1,TJP2,SLC25A27,BTF3L4,COL9A2,IFFO1,NXPH1,CSF3R,FEZ2,FEZ1,PHACTR3,PRKACB,IGSF1,CTNND2,WBP1L,SYNC,LRRTM3,SIRPA,PTCH1,PLPPR1,BDNF-AS,PTHLH,BLOC1S6,OCIAD1,PTPRD,PLPPR4,PTPRZ1,KIF2A,FAM13C,DTNA,PAK5,ABCC9,RET,RLBP1,SEC61A2,RPRD1A,RAVER2,SLC4A10" MicroRNA hsa-miR-29c:mirSVR_lowEffct hsa-miR-29c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-43 1.19E-39 1.10E-41 1.01E-40 108 1652 "PAQR6,KCNIP2,NDRG2,ADCY2,SLITRK1,WAC,SORCS1,HOGA1,LRRC7,SEMA6A,HPCAL4,MOG,ERICH3,CDC42BPA,ANK3,PPM1E,DOCK10,DGKZ,DGKD,ZCCHC17,ZNF365,RPH3A,PKNOX2,ARHGAP5,LGI3,NAXD,MTR,SORCS3,KBTBD12,ATM,SCN3B,SON,ZSWIM8,ADAM15,C11orf87,ZNF302,ERBIN,ADHFE1,NFIA,PCDH11X,GNAS,CAMSAP2,CACNA1A,FAM69C,CACNA1E,NPPA,PRLHR,CAMK2G,CECR2,BRSK2,GRIA2,GRIA4,GRIK2,ZFP91,KCNK10,DAAM2,CD81,PAX6,CDC42,DCLK1,ARHGAP19,LILRA4,PDE3B,ZMYND8,CASC2,CHRNB2,KIAA1549L,NEGR1,UBTF,NMT2,SULT4A1,BTF3L4,IFFO1,NSD2,MFSD4A,CP,OSBPL3,ATRNL1,FMN2,KIAA1755,CTNND1,NRSN1,FAM131B,WBP1L,TOMM20,TUBB2B,ZNF385B,SIRPA,CADM2,PRDM2,CSDE1,PLPPR4,PCDH15,PEX5,DLG2,NKAIN1,TMEM255A,SLC25A48,FAM66C,FAM57B,ABI1,ZYG11B,RET,SIDT2,VWA5A,LPAR6,YY1AP1,SEZ6" MicroRNA hsa-miR-4298:mirSVR_lowEffct hsa-miR-4298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-43 1.19E-39 1.10E-41 1.01E-40 109 1684 "SYT9,LGR4,ARID1A,WLS,MDM4,KCNIP2,SLC25A25,NDRG2,ADARB2,PNMA8B,NLGN4X,CHST15,HOGA1,SCN4B,KIAA1109,ASIC4,TRIM46,SFPQ,CDC42BPA,PPFIA1,SORBS1,API5,SHTN1,PAAF1,ZNF365,SLC2A5,SCMH1,CGREF1,NAXD,ASPH,SORCS3,RCOR3,TMEM151A,NRG3,FYN,GABBR1,SOX10,GAD2,ZSWIM8,FXYD6,NPAS3,ALDH1L1,GFAP,GFRA1,ADHFE1,FAM168A,MLC1,PCDH11X,NHLH1,CDK5R2,KLHL4,TBX15,WSCD1,CACNA1E,CACNB2,TCF12,NUCB1,NUMA1,RFFL,OLR1,CRB1,P2RX7,PC,CDC42,TNS1,LGI1,MAGI1,ADGRG1,PLEKHB1,HEPACAM,DLGAP3,GDAP1L1,FTO,BEST1,PRRX1,P2RY12,FAT3,MFSD4A,SNCAIP,OSBPL3,PLCH2,PRKCG,IGSF1,EDRF1,KIAA0408,MASP1,SPIRE1,SYNC,PRDM2,PRTFDC1,BLOC1S6,PTPRE,RABGAP1L,KCNMA1,DLG2,SLC17A6,ATG16L1,GOPC,SLC6A15,NUP214,JMJD1C,PHC2,ZNF248,VANGL2,SIDT2,YY1AP1,EPB41,EPB41L1,BAALC" MicroRNA hsa-miR-29b:mirSVR_lowEffct hsa-miR-29b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.84E-43 2.08E-39 1.91E-41 1.75E-40 111 1759 "PAQR6,KCNIP2,NDRG2,RTN1,ADCY2,SLITRK1,WAC,SORCS1,HOGA1,LRRC7,HPCAL4,MOG,ERICH3,CDC42BPA,ANK3,PPM1E,DOCK10,GAS7,DGKZ,DGKD,ZCCHC17,ZNF365,RPH3A,PKNOX2,ARHGAP5,LGI3,NAXD,MTR,SORCS3,KBTBD12,ATM,SCN3B,SON,ZCCHC24,ZSWIM8,ADAM15,FXYD6,C11orf87,ZNF302,ERBIN,NFIA,PCDH11X,GNAS,CAMSAP2,CACNA1A,FAM69C,CACNA1E,NPPA,NEU4,PRLHR,CAMK2G,CECR2,BRSK2,GRIA2,GRIA4,GRIK2,ZFP91,KCNK10,DAAM2,CD81,PAX6,CDC42,DCLK1,ARHGAP19,LILRA4,PDE3B,ZMYND8,CASC2,CHRNB2,KIAA1549L,NEGR1,UBTF,NMT2,SULT4A1,BTF3L4,IFFO1,NSD2,MFSD4A,MICAL2,ATRNL1,FMN2,KIAA1755,CTNND1,NRSN1,FAM131B,WBP1L,TOMM20,TUBB2B,ZNF385B,SIRPA,CADM2,CSDE1,PLPPR4,PCDH15,PEX5,DLG2,NKAIN1,TMEM255A,SLC25A48,FAM66C,PARP11,FAM57B,ABI1,ZYG11B,RET,SIDT2,VWA5A,LPAR6,YY1AP1,EPB41L1,SEZ6" MicroRNA hsa-miR-335:mirSVR_lowEffct hsa-miR-335:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-43 2.60E-39 2.36E-41 2.17E-40 117 1963 "TTYH1,LOC100128239,RBM10,APC2,MDM4,CSMD3,ADAR,ADD3,FABP7,FOXRED2,CHST15,TOMM40L,HOGA1,LRRTM4,UNC79,AMPH,ERICH3,RASA3,USP28,PPFIA1,ITSN1,PPM1E,DOCK10,SORBS1,API5,AQP4,MIER1,RUFY2,SLC8A3,GPR153,CSPG5,SPHKAP,LGI3,NAXD,MTR,SMARCE1,ALDH4A1,IGSF9B,NRG3,EIF4G3,MYT1L,AHCYL1,JPH4,FXYD6,NPAS3,NCAM1,C11orf87,BCL2L2,ALDH1L1,NEUROD1,RHBDL3,POPDC3,DCLK2,CAMTA1,GNG4,UNC5D,WWC1,GPM6B,TCF7L2,TCF12,NUDT21,CAMK2G,PSD3,GRIA4,GRID1,GRIK2,LINC00839,P2RX7,TJP1,ZFP91,TNR,PCDH8,ZMYND8,BEST3,PFKFB3,CASC2,MS4A7,CADM1,ANLN,FADS2,DNAJC12,MEAF6,IFFO1,FAT3,CRMP1,FEZ2,RAB39A,PUM1,ECE2,LRRTM3,BDNF-AS,PRTFDC1,COPS7A,STMN4,OLFM3,SRGAP3,NTM,RABGAP1L,WIPF2,DNM2,PLEKHB2,RASGRF1,DTNA,JMJD1C,ARHGEF10L,PHC2,TTLL7,SYT15,SEC61A2,SSPN,CACNG7,EFNA3,YY1AP1,PRRT4,EPB41L2,RCAN2,RASGRP2" MicroRNA hsa-miR-182:mirSVR_highEffct hsa-miR-182:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.34E-43 2.89E-39 2.59E-41 2.37E-40 107 1636 "SDE2,MAP6,SYNDIG1,ATAT1,ADCY2,ADD3,SLC44A5,GPR158,SNX32,FGF1,LRRC7,PDZD4,SOX6,CDC42BPA,ANK3,PPM1E,APBA2,DOCK10,APC,NTNG1,GPAM,SLC1A6,LRRC55,CADPS,TAGLN3,ASPH,ATP1A2,NRG3,PALLD,MEGF11,MYT1L,AHCYL1,NASP,LMO3,STOX1,NELL1,RGL1,ADHFE1,ARHGEF7,POPDC3,CAMTA1,CAMSAP2,ADGRL3,PRUNE2,ATF7,CACNA1E,CACNB2,LILRA1,PRLHR,NUDT21,EML4,SYT6,OMG,TGFBR3,PC,TNR,C1orf94,PCDH8,LGI1,MAGI1,PDE1A,ACOT7,BEST3,PFKFB3,CADM1,ANLN,A2ML1,TJP2,PMP2,MEAF6,SLC25A27,P2RY12,SLC36A4,CHD1L,MED1,MICAL2,PRKACB,DZIP3,NRSN1,FGFR1OP2,SPIRE1,TOMM20,PSMD13,PTCH1,CA10,PTHLH,CADM2,ELMO1,HP1BP3,OCIAD1,PTPRZ1,KCNK2,KCNMA1,KCNN3,DLG2,DNAH9,C12orf4,DSCAM,FAM13C,RTN4,L1CAM,SLC6A15,ZYG11B,RET,RFX4,JMJD1C,RPRD1A" MicroRNA hsa-miR-1224-3p:mirSVR_lowEffct hsa-miR-1224-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.35E-43 2.90E-39 2.59E-41 2.37E-40 108 1668 "DPF1,RABEPK,SDE2,LOC100128239,ASIC1,EXTL1,KCNIP2,SLC25A25,KLHL32,RTN1,GALNT13,FABP7,ERMN,TMEM156,ADORA3,FHL1,FOXM1,TRIM46,ASRGL1,ANK2,USP28,SHTN1,CLSTN1,SLC1A6,SLC1A7,MSR1,LRRC55,MT3,SCMH1,DNAH17,NAXD,CAPRIN2,SMARCE1,RCOR3,MEGF11,MYBPC1,TNIK,JPH4,ADAM15,KIF1B,FXYD6,SMOC1,RND1,SEPT3,VAMP1,RHBDL3,NHLH1,OS9,ASTN2,CDK5R2,UNC5D,WSCD1,GPM6B,AZIN2,GRIA1,GRIA2,CYB561A3,MFSD2A,ZDHHC22,TNR,TPD52,PDE2A,PRMT8,PIRT,FNDC5,CHRM1,HERC2P3,ARHGAP22,GDAP1L1,UBTF,PACSIN1,IFFO1,NSD2,ETNPPL,MICAL2,RBPJ,PLPP4,PLD5,CTNND1,ECE2,KIAA0408,ZBTB16,SPIRE1,TOMM20,DNAJC6,COPS7A,CEP170,STMN4,PTPRE,PLPPR4,KCND3,AK5,KCNJ10,KCNJ11,ARNT2,DLG3,WIPF2,ATG16L1,RAP1GAP,GOPC,DSCAM,RFX4,JMJD1C,ZNF248,SIDT2,ELAVL4,EN2,SEZ6" MicroRNA hsa-miR-3116:mirSVR_lowEffct hsa-miR-3116:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-43 2.96E-39 2.62E-41 2.41E-40 110 1733 "ZFYVE27,SYT9,PAQR6,EXTL1,MEG3,MRVI1,KLHL32,AMER2,CHST15,KIAA1109,PLA2G6,HPCAL4,MOBP,FOXG1,FOXM1,TRIM46,ASRGL1,ANK1,RASA3,PI16,ITSN1,PKP4,APBB1,NTNG1,DGKD,ZCCHC17,SLC1A7,MADD,LRRC55,SLC6A9,SLC8A2,SCMH1,LGI3,ASTN1,CADM3,AHCYL1,ENKUR,B4GALNT1,NCAM1,STOX1,SMOC1,INKA2,PHLDB1,GANAB,ZNF638,SYT4,MYRF,MMD2,CNTN2,ANO4,CACNA1E,DDR1,HAP1,NUDT21,GRID1,ADAMTS8,LINC00839,TGFBR3,GUCY1A1,ZDHHC22,DAAM2,IGSF21,PADI2,HRH3,LGI1,PIRT,TMPRSS5,CHRM1,ARHGAP22,NOMO2,CCSER2,C11orf49,PMP2,CELF5,BEST1,PRRX1,PNKD,PTPA,SNCAIP,OSBPL3,RBPJ,PRKAB2,CMTM5,CTNND1,FAM131B,NOS1AP,MASP1,SIRPA,MAGI2,STMN4,BLOC1S6,KCNA6,KCNC1,C1orf109,AK5,KCNJ10,TMCC2,KCNK1,SNX27,DLG2,SLC25A48,DNM2,FAM66C,SUSD4,RASGRF1,PAK5,PHC2,SIDT2,ELAVL3,EPB41L1" MicroRNA hsa-miR-455-5p:mirSVR_lowEffct hsa-miR-455-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.64E-43 3.60E-39 3.16E-41 2.90E-40 100 1422 "SYT9,SYNDIG1,ARID1A,MDM4,F3,ADARB2,ADCY2,GALNT13,HOGA1,SEMA6A,ASIC4,FHL1,ANXA7,DOCK10,DGKD,SLITRK3,CACHD1,NLGN1,ST8SIA1,AQP4,ZNF365,URGCP,SLC6A9,CAPRIN2,RCOR3,ATM,NRG3,SON,KIF21B,CAB39,ENKUR,IDI2-AS1,ADAM15,KIF1B,NAP1L2,NPAS3,NFASC,BCL2L2,RGL1,ARHGEF7,GLS,PCDH11X,MMD2,ADGRL3,TMEM136,CNDP1,ANO4,ACSL6,AZIN2,PTBP2,NUDT21,CAMK2A,GPR88,ATP13A2,OPCML,LINC00839,TGFBR3,TMEM257,CHGA,TUB,CADM1,CAMKV,NMT2,ACBD5,POU3F2,PPP2R5C,TENM4,RGS6,KCNT2,ATRNL1,VCAN,DOCK7,PLPP4,CTNND1,NRSN1,MAPK10,KIAA0408,BRINP3,ZBTB16,TOMM20,ZNF385B,SYNC,PTHLH,STMN4,KCNA4,PTPRE,CCDC3,KCNN3,PID1,SUSD4,ABCC9,SLC6A15,JMJD1C,ATL1,TTLL7,RNF220,SH3GLB1,LMO1,SLC4A10,BAALC" MicroRNA hsa-miR-1275:mirSVR_lowEffct hsa-miR-1275:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.29E-43 3.95E-39 3.43E-41 3.15E-40 113 1837 "PRR5L,ASIC1,SYT9,EXTL1,MRVI1,LDLRAD3,ADCY2,PNMA8B,ADORA3,AMER2,FOXRED2,PLA2G6,SEMA6A,ASIC4,UNC79,TRIM46,AMPH,USP28,CNIH2,ANXA7,PKP4,MAGI3,SORBS1,STK32C,PAAF1,ARHGAP5,ARFGAP2,SLC8A2,CGREF1,SLCO1A2,ASPH,TMEM151A,NRG3,SOX10,ZSWIM8,ENKUR,ARPP21,ADGRB2,FXYD6,NCAM1,ALDH1L1,GFRA1,NCDN,INKA2,SEPT3,NFIA,RHBDL3,CASTOR3,PCDH11X,GNAS,CAMTA1,GOLGB1,CNDP1,ANO4,WSCD1,TCF7L2,HAP1,BRSK2,GRIA1,GRIA4,CYB561A3,SHISA7,TIE1,CELF3,ZDHHC22,PAX6,PTGDR2,PCSK2,MAGI1,TUB,HNRNPK,JAM2,DLGAP3,GDAP1L1,NRXN2,UBTF,FADS2,FLRT1,FTO,C11orf49,COL9A2,PRRX1,NECAB2,NSD2,FAAP20,PNKD,SF1,NCAN,SDC3,IGSF1,CTNND1,PLPPR5,ZNF385B,PRDM2,HP1BP3,COPS7A,BLOC1S6,KCNJ4,CCDC3,NKAIN1,DNAH9,DNM2,FAM57B,ATG16L1,SUSD4,GNE,DTNA,SYT15,SEC61A2,EFNA3,ABI2,ELAVL4,EPB41L1" MicroRNA hsa-miR-29a:mirSVR_lowEffct hsa-miR-29a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.28E-43 4.48E-39 3.87E-41 3.55E-40 106 1612 "EMID1,PAQR6,KCNIP2,NDRG2,SLITRK1,WAC,SORCS1,HOGA1,LRRC7,SEMA6A,HPCAL4,MOG,CDC42BPA,ANK3,PPM1E,DOCK10,DGKZ,DGKD,ZCCHC17,ZNF365,RPH3A,PKNOX2,ARHGAP5,LGI3,SORCS3,KBTBD12,ATM,SCN3B,SON,ZSWIM8,ADAM15,FXYD6,C11orf87,ZNF302,ERBIN,DCAF5,ADHFE1,NFIA,PCDH11X,GNAS,CAMSAP2,CACNA1A,FAM69C,CACNA1E,NPPA,PRLHR,CAMK2G,CECR2,BRSK2,GRIA2,GRIA4,GRIK2,TMEM257,ZFP91,KCNK10,DAAM2,CD81,PAX6,CDC42,DCLK1,ARHGAP19,LILRA4,ZMYND8,CASC2,CHRNB2,NEGR1,UBTF,NMT2,SULT4A1,BEST1,BTF3L4,IFFO1,NSD2,MFSD4A,CP,ATRNL1,FMN2,KIAA1755,CTNND1,NRSN1,NOS1AP,WBP1L,TOMM20,TUBB2B,ZNF385B,SIRPA,CADM2,CSDE1,PLPPR4,PCDH15,PEX5,DLG2,NKAIN1,TMEM255A,SLC25A48,FAM66C,PARP11,FAM57B,ABI1,ZYG11B,RET,SIDT2,VWA5A,LPAR6,YY1AP1,SEZ6" MicroRNA hsa-miR-412:mirSVR_lowEffct hsa-miR-412:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.58E-43 4.65E-39 3.97E-41 3.64E-40 112 1807 "MAG,LOC100128239,PRR5L,MAP6,LGR4,PAQR6,AMER2,KIAA1109,LRRC7,GOLGA7B,SELL,ANK2,ANK3,PI16,GPAM,BCAN,ST3GAL3,ZNF365,ARFGAP2,SLC8A3,MT3,SCG3,SLCO1A2,ARFGAP1,CAPRIN2,ASPH,RCOR3,SNAP25,PALLD,CADM3,IDI2-AS1,KIF1B,ALDH1L1,ERBIN,RGL1,ADHFE1,VAMP1,LUZP2,DCLK2,GNAS,NODAL,CACNA1E,LILRA1,TCF7L2,PTBP2,CECR2,BRSK2,GRIA1,GRIA2,GRIA4,RFFL,CYB561A3,SPX,P2RX7,TJP1,TLL2,CDK11B,SEZ6L,LGI1,TPM3,PCSK2,PDE4B,FNDC5,CHGA,TUB,HERC2P3,HNRNPK,HEPACAM,CADM1,CPT1C,PLXNB3,CELF5,SLC25A27,PRRX1,P2RY12,IFFO1,RNF14,TENM4,PLCH2,PRKACB,KIAA0513,WBP1L,SYNC,LRRTM3,DKFZp779M0652,COPS7A,CSDE1,STMN4,ZC3H11A,SMG7,KCNJ9,KCNJ10,KCNJ11,CCDC3,KCNK1,KCNK2,KCNMA1,WIPF2,DNM2,PARP11,DBX2,ZYG11B,CAMK1G,NUP214,RFX5,RGR,RGS7,ARHGEF10L,SEC61A2,RPRD1A,EPB41,RCAN2" MicroRNA hsa-miR-30c:mirSVR_highEffct hsa-miR-30c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-42 6.67E-39 5.65E-41 5.19E-40 116 1948 "MAP6,CDHR1,CNTNAP3,SYT9,RCSD1,ARID1A,CSMD3,RTN1,GALNT13,CDC7,FABP7,SORCS1,ERMN,SCN3A,LINC00461,SLC30A10,FOXG1,ERICH3,SGIP1,ITSN1,DOCK10,MAGI3,SORBS1,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,SMARCE1,RCOR3,TMEM108,ATM,NRG3,ATP2B2,SON,JPH4,KIF1B,NAP1L2,NPAS3,SPART,CLASP2,ERBIN,RGL1,SEPT3,GLS,SYT4,GNAS,DDHD2,CAMTA1,ADGRL3,ANO4,PRUNE2,CACNB2,GPR19,EML4,CECR2,GRIA2,RFFL,GRM3,OMG,CRB1,USP2,TLL2,CELF3,PCDH9,LGI1,MAGI1,PIRT,ZMYND8,MS4A7,ZBED5,TMEFF2,NEGR1,PIK3CD,MICAL1,ACBD5,PNKD,OSBPL3,PRKACB,DOCK7,DZIP3,RAB39A,CTNND2,TOX,SPIRE1,TOMM20,LRRTM3,CA10,JAKMIP2,CEP170,CSDE1,MAGI2,BLOC1S6,PLPPR4,PTPRZ1,RABGAP1L,PARP11,RALGDS,PAK5,ABCC9,RGS7,FAM135B,INSYN2,TTLL7,SEC61A2,RNF220,RPRD1A,RAVER2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-653:mirSVR_highEffct hsa-miR-653:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.27E-42 6.86E-39 5.76E-41 5.29E-40 102 1494 "EPS8,PRR5L,ADGRV1,ARID1A,CLIP1,KLRC4,SLITRK1,ADD3,WAC,ERMN,FCGR1A,FCGR1B,SCN3A,LRRC7,HPCAL4,MOBP,MOG,SGIP1,CDC42BPA,ITSN1,APC,MAGI3,ZNF365,MIER1,RUFY2,MSRA,ARHGAP5,CCDC88A,DACH2,SCG3,SLCO1A2,ASPH,SORCS3,SMARCE1,RCOR3,FYN,PHYHIPL,B3GALT2,SOX5,CAB39,NCAM1,LMO3,NDUFA5,DCAF5,RCOR2,NELL1,NEUROD1,NFIA,PCDH11X,POPDC3,LUZP2,ANO4,GPM6A,LILRA1,TCF7L2,GRIA1,GRIK2,TMEM25,MFSD2A,AIFM1,CELF3,TMEM257,PADI2,PDE1A,CASC2,HNRNPK,JAM2,UBTF,A2ML1,SLC36A4,NXPH1,CP,POU3F2,ATRNL1,RBPJ,DOCK7,CTNND2,PROX1,MASP1,BDNF-AS,CADM2,OLFM3,OCIAD1,PTPRD,PLPPR4,PTPRO,PTPRZ1,KCNJ10,KCNMA1,DLG2,PARP11,SLC25A18,SUSD4,RTN4,SLC6A15,ZYG11B,JMJD1C,FAM135B,SLC39A12,GPR61,RERGL,RCAN2" MicroRNA hsa-miR-96:mirSVR_lowEffct hsa-miR-96:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-42 7.38E-39 6.15E-41 5.64E-40 110 1750 "EPS8,SYT9,MDM4,SLC25A25,AMER2,SLC44A5,LRRTM4,SEMA6A,FGR,SELL,CDC42BPA,ANK3,ANXA7,PKP4,APC,NTNG1,SLITRK3,SORBS1,ZNF365,SLC8A3,MT3,CCDC88A,SLC14A1,DACH2,CGREF1,MTR,SORCS3,ASTN1,SMARCE1,ATP1A2,PALLD,B3GALT2,NPAS3,SPART,NCAM1,STOX1,GFRA1,NELL1,GJB1,NEUROD1,LUZP2,CAMTA1,CAMSAP2,MYRF,CDK5R2,MMD2,ADGRL3,ANO4,PRUNE2,ATF7,CACNB2,PRLHR,TCF12,OLR1,MFSD2A,INA,ZDHHC22,PAH,TNR,PADI2,TNS1,PCDH8,ARHGAP19,ZNF384,PRMT8,HMGB1,CADM1,NRXN1,CCSER2,P2RY12,NSD2,SNCAIP,MICAL2,ATRNL1,RBPJ,PRKAB2,FMN2,NRSN1,MASP1,TOX,PLPPR5,PMEPA1,BDNF-AS,PTHLH,ELMO1,PRDM2,CEP170,PTPRZ1,KCNMA1,KCNN3,KIF2A,HS3ST4,SLC25A48,SLC17A6,PLEKHB2,RALGDS,ATG16L1,C12orf4,DTNA,RTN4,PAK5,RET,RFX4,INSYN2,ARHGEF10L,ZNF248,RNF220,RPRD1A,OLIG2,EPB41L2" MicroRNA hsa-miR-4303:mirSVR_lowEffct hsa-miR-4303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.79E-42 9.68E-39 8.00E-41 7.34E-40 111 1788 "TTYH1,ACER3,MAP6,ACHE,LGR4,MRVI1,MDM4,ADAR,CLIP1,ERMN,TMEM156,FCGR1A,TOMM40L,SEMA6A,ASIC4,CDC42BPA,APBA2,DOCK10,NTNG1,DGKD,TACC2,CACHD1,NLGN1,ST3GAL3,PAAF1,ZNF365,URGCP,LRRC55,CCDC88A,ASCL1,SLIT1,NAXD,SORCS3,SMARCE1,ALDH4A1,SNAP25,FYN,MEGF11,DKK3,MYT1L,KIF21B,SALL3,ADAM15,COLGALT2,GPR162,HEPN1,ARHGEF7,VAMP1,CASTOR3,KAZN,ROBO3,GNG3,NODAL,MYRF,ADGRL3,KLHL4,ATF7,NUDT21,EML4,GRIA2,CYB561A3,LEFTY2,MFSD2A,TJP1,ZFP91,PAX6,TNFRSF1B,PDE3B,PDYN,HMGB1,CASC2,HERC2P3,NSD2,FAT3,NXPH1,POU3F2,CHD1L,KCNT2,OSBPL3,NCAN,PHACTR3,PRKACB,DZIP3,RAB39A,TOX,SYTL2,SYNC,PSMD13,PTCH1,PMEPA1,CNIH3,CEP170,MAGI2,KCNMA1,DLG3,RAB5B,ATG16L1,RASGRF1,ABCC9,NUP214,ARHGEF10L,PHC2,VANGL2,SYT15,SFXN5,EFNA3,ELAVL4,RPE65,PRRT4,EPB41L1,RCAN2" MicroRNA hsa-miR-362-5p:mirSVR_lowEffct hsa-miR-362-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-42 1.15E-38 9.44E-41 8.66E-40 116 1959 "EPS8,PRR5L,MAP6,CNTNAP3,SYT9,RTN3,ACTN2,MRVI1,CSMD2,MDM4,GALNT13,FABP7,TESK2,FGF1,TRIM46,USP28,PPFIA1,SESN3,DGKZ,SORBS1,CACHD1,SHTN1,URGCP,LRRC55,PKNOX2,CCDC88A,NSG2,CADPS,CAPRIN2,SMARCE1,RCOR3,TMEM108,ATM,EIF4G3,PHYHIPL,DKK3,KIF21B,NMNAT2,ENKUR,IDI2-AS1,DNER,SPART,SMOC1,GJB1,GLS,DCLK2,KAZN,DDHD2,CAMTA1,CAMSAP2,UNC5D,CLEC9A,EML4,CAMK2A,VXN,VSTM2A,GRIA2,GRIA4,GRIK2,OLR1,CRB1,INA,MAEL,LGI1,TPD52,MAGI1,ZNF384,PDE1C,IGFN1,PRMT8,FNDC5,GPR37L1,HPSE2,CHGA,CASC2,MS4A7,CADM1,ZFYVE9,A2ML1,PMP2,PRRX1,SPATA6,FAT3,NXPH1,MFSD4A,PPP3CB,ATRNL1,RBPJ,FMN2,PKN2,PRKCZ,NOS1AP,FGFR1OP2,ANKS1B,PTAFR,DNAJC6,ELMO1,PTPRZ1,NTM,KCNK1,RAD52,FAM66C,FAM13C,DTNA,RET,USH1C,RFX5,RGR,ZNF248,VANGL2,EFNA3,RBM12,ABI2,TMEM100,RCAN2,UEVLD" MicroRNA hsa-miR-137:mirSVR_highEffct hsa-miR-137:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.15E-42 1.16E-38 9.44E-41 8.66E-40 106 1629 "SERPINA3,SRARP,LGR4,SYNDIG1,ADGRV1,MDM4,CSMD3,ADORA3,FCGR1A,FCGR1B,TOMM40L,LRRTM4,KIAA1109,UNC79,MOBP,ITSN1,ANXA7,NTNG1,BCAN,AQP4,ZNF365,SLC6A9,DACH2,CADPS,ASPH,SMARCE1,ATM,NRG3,PHYHIPL,ATP2B2,MEGF11,DKK3,USP33,SOX1,B3GALT2,AHCYL1,NMNAT2,ENKUR,TTLL9,GART,FXYD6,NCAM1,C11orf87,GPR162,ERBIN,RCOR2,KIRREL3,NEUROD1,SLCO1C1,ARHGEF7,GLS,ZNF638,LUZP2,GNAS,CAMTA1,KLHL4,ANO4,ACSL6,TCF12,GRIA4,GPR88,PTPN5,TJP1,TMEM257,MAEL,TNS1,DCLK1,FNDC5,HAPLN2,BEST3,NRXN1,TJP2,BTF3L4,SLC36A4,FAT3,FAAP20,MED1,PNKD,RGS6,KCNT2,NCAN,RBPJ,PRKACB,RAB39A,PKN2,PLD5,BRINP3,WBP1L,ANKS1B,ZNF385B,CA10,PRDM2,ZC3H11A,KCNA2,NKAIN1,SLC17A6,DTNA,RTN4,ABCC9,FAM135B,RBM12,CBLN2,RAVER2,RPE65,PRRT4,RCAN2" MicroRNA hsa-miR-579:mirSVR_highEffct hsa-miR-579:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.20E-42 1.19E-38 9.62E-41 8.82E-40 114 1892 "ACER3,MAPT,SYT9,SYNDIG1,ACTN2,IL17D,WLS,MDM4,CSMD3,ADARB2,RTN1,DSCAML1,ADD3,ERMN,FCGR1A,SCN3A,LRRTM4,FGF14,BCAR3,BBOX1,MOBP,PPFIA1,ANXA7,PKP4,APC,NTNG1,GPAM,SORBS1,NLGN1,LRRC4C,BCAS1,SHTN1,MSR1,ARHGAP5,CADPS,SLCO1A2,SMARCE1,RCOR3,SNAP25,EIF4G3,DKK3,TNIK,SOX5,ZCCHC24,ARPP21,NPAS3,NCAM1,CLASP2,ERBIN,ADHFE1,FAM168A,ARHGEF7,VAMP1,GNAS,CAMTA1,ANO4,GPM6B,VWC2,B4GALNT4,AKNA,GRIA4,GPR88,OMG,AIFM1,TMEM257,CDC42,CDH8,CDH10,LGI1,MAGI1,ANO5,CASC2,A2ML1,OPALIN,CNTN1,P2RY12,ACBD5,POU3F2,ATRNL1,NCAN,RBPJ,PRKACB,FMN2,PKN2,IGSF1,CTNND1,SPIRE1,TUBB2B,LRRTM3,BDNF-AS,PTHLH,CADM2,PRTFDC1,CEP170,BLOC1S6,KCNA4,PTPRD,PLPPR4,KCNH1,NTM,RABGAP1L,DLG2,KLRC3,TMEM255A,SLC17A6,DPP6,GOPC,FAM13C,DTNA,ABCC9,SSPN,SH3GLB1,VWA5A,EPB41L2" MicroRNA hsa-miR-4299:mirSVR_lowEffct hsa-miR-4299:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.68E-42 1.45E-38 1.15E-40 1.06E-39 109 1730 "TTYH1,EPS8,SERPINA3,MAPT,MBP,CNTNAP3,SYT9,LGR4,MRVI1,RTKN,CSMD3,PLEKHG5,ADCY2,GALNT13,ERMN,FCGR1B,TESK2,LRRTM4,BBOX1,ERICH3,CDC42BPA,ANK1,SH3GL2,CCDC80,ST3GAL3,ZNF365,RPH3A,SLC2A5,ARHGAP5,SCMH1,ARFGAP1,ATM,PALLD,SCN3B,USP33,WDTC1,GAD2,NMNAT2,ARPP21,SPART,NFASC,NCAM1,SMOC1,RGL1,ADHFE1,RND1,ARHGEF7,VAMP1,CASTOR3,NHLH1,DCLK2,KAZN,WWC1,ACSL6,AZIN2,PTBP2,CAMK2G,GRIA4,SHISA7,CCKBR,PTPN5,TMEM25,GUCY1A1,ZFP91,CDC42,PADI2,CDH8,RBFOX2,PDE3B,PRMT8,LRTM2,ASIC3,CHRM1,CASC2,CADM1,OPALIN,CELF5,PNKD,SF1,CSF3R,FEZ1,VCAN,NCAN,RBPJ,KIAA1755,RAB39A,PRKCZ,ECE2,FGFR1OP2,BRINP3,KIAA0513,CA10,PMEPA1,BDNF-AS,ELMO1,PRDM2,HP1BP3,CSDE1,PTPRE,TMCC2,KCNMA1,RALGDS,RASGRF1,BSDC1,RFX4,JMJD1C,SEC61A2,RBM12,FGFBP3" MicroRNA hsa-miR-877:mirSVR_lowEffct hsa-miR-877:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.68E-42 1.45E-38 1.15E-40 1.06E-39 103 1538 "DPF1,ASIC1,MEG3,ATAT1,CSMD2,WLS,CSMD3,RXRG,GALNT13,ADD3,SORCS1,NLGN4X,SLC44A5,SCN4B,FGF1,ELMOD1,SGIP1,DGKZ,BCAN,TACC2,MADD,RUFY2,CADPS,GPR153,SLCO1A2,SPHKAP,LGI3,TAGLN3,ASPH,ASTN1,TMEM108,ATM,SON,ARPP21,KIF1B,NPAS3,NFASC,NCAM1,BCL2L2,GJB1,NEUROD1,CAMSAP2,WWC1,TCF12,PTBP2,AKNA,GRIA1,CYB561A3,LINC00839,CRB1,TMEM25,TMEM9,AIFM1,CELF3,PAX6,ZNF384,PDE1C,PDYN,FNDC5,CA14,LRTM2,ASIC3,HNRNPK,NMT2,OPALIN,ST8SIA5,MEAF6,FAT3,PNKD,PPP2R5C,SNCAIP,MICAL2,ATRNL1,PRKACB,CMTM5,HES5,MASP1,LRRTM3,PLPPR1,PRDM2,PRTFDC1,PTPRD,KCNC1,KCNJ10,KCNK1,KCNK2,DLG2,NKAIN1,WIPF2,DNAH9,C12orf4,GNE,L1CAM,ABCC9,SLC6A15,ZYG11B,RFX5,TTLL7,SSPN,SIDT2,YY1AP1,EPB41L1,RCAN2" MicroRNA hsa-miR-624:mirSVR_lowEffct hsa-miR-624:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.02E-42 1.63E-38 1.29E-40 1.18E-39 111 1798 "EPS8,LOC100128239,EYA1,KCNIP2,CSMD3,CLIP1,ADORA3,FOXRED2,SLC44A5,TOMM40L,HOGA1,LRRC7,FGR,FHL1,GOLGA7B,ELMOD1,SFPQ,ANK1,CNIH2,BCAS1,PAAF1,LRRC55,DACH2,ASCL1,ASPH,BRINP2,SMARCE1,RCOR3,TMEM108,SNAP25,NRG3,CAB39,ARPP21,KIF1B,CPLX2,NAP1L2,NCAM1,C11orf87,HEPN1,ACSBG1,ARHGEF7,CASTOR3,CAMTA1,ATF7,ZEB1,DIRAS1,CAMK2G,PSD3,AKNA,OLR1,TMEM25,TGFBR3,MFSD2A,NEURL1,ZDHHC22,CD81,MAEL,PAX6,PCDH8,PTGDR2,TPD52,ZNF384,PDE1A,ASIC3,HNRNPK,TMEFF2,JAM2,ARHGAP22,NEGR1,CCDC136,MEAF6,NXPH1,ACBD5,CHD1L,CRMP1,SNCAIP,TENM4,NKAIN4,KCNT2,PKN2,CTNND2,TOX,TOMM20,SIRPA,ITGAV,CA10,BDNF-AS,CNIH3,PRDM2,COPS7A,KCNA4,KCNA6,AK5,RABGAP1L,KCNK2,KCNMA1,KCNN3,DLG2,DLG3,KIF2A,SUSD4,BSDC1,ABCC9,RFX4,RGR,ZNF248,SYT15,SSPN,PIANP,CBLN2,EN2" MicroRNA hsa-miR-500:mirSVR_lowEffct hsa-miR-500:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.14E-42 1.70E-38 1.33E-40 1.22E-39 114 1899 "EPS8,LOC100128239,MAPT,ACTN2,MDM4,ADAR,SLITRK1,CDC7,FOXRED2,TOMM40L,HOGA1,KIAA1109,SEMA6A,BCAR3,SOX6,SELL,FOLH1,NTNG1,SORBS1,NLGN1,SHTN1,ZNF365,SFMBT2,MSR1,ARHGAP5,SLC8A3,CCDC88A,SLC14A1,DACH2,PDE8B,SCG3,SLCO1A2,CAPRIN2,MTR,ASTN1,SMARCE1,B3GALT2,ZSWIM8,ENKUR,NEK6,TTLL9,IDI2-AS1,NPAS3,NASP,ALDH1L1,SMOC1,SEPT3,ZNF638,KAZN,CAMSAP2,UNC5D,BTRC,ZEB1,EML4,VXN,PSD3,GRIA2,GRIA4,CRB1,INA,TJP1,REPS2,PCDH9,TPD52,TPM4,MAGI1,ZNF384,IGFN1,GPR37L1,ANO5,MS4A7,JAM2,HPCA,CADM1,NRXN2,PIK3CD,CPT1C,A2ML1,CNTN1,MEAF6,PRRX1,FAT3,MFSD4A,POU3F2,SNCAIP,PPP3CB,NCAN,RAB39A,PKN2,HES5,FGFR1OP2,GON4L,ZNF385B,PTCH1,BDNF-AS,PTHLH,CEP170,PTPRD,NTM,RABGAP1L,KCNJ10,KCNMA1,PLEKHB2,ABI1,FAM13C,SLC6A15,RGR,INSYN2,VANGL2,SEC61A2,SLC4A10,ELAVL3,RPE65,UEVLD" MicroRNA hsa-miR-1260:mirSVR_lowEffct hsa-miR-1260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-42 1.81E-38 1.41E-40 1.29E-39 111 1800 "SDE2,LGR4,IL17D,MDM4,RTN1,GALNT13,PNMA8B,GRAMD1B,TMEM156,FCGR1A,LINC00461,FGF14,ASIC4,FHL1,UNC79,MOBP,PDZD4,SOX6,FOXM1,TRIM46,ASRGL1,GPAM,ST3GAL3,SLC1A6,RUFY2,SLC6A9,SLC14A1,KBTBD12,TMEM108,ATP2B2,MEGF11,GABBR1,NMNAT2,JPH4,EMC1,ALDH1L1,SMOC1,DCAF5,VAMP1,C1QC,DCLK2,CDK5R2,CACNB2,TMEM151B,NUMA1,GRIA1,GRIA2,GRIA4,CYB561A3,PTPN5,DAAM2,DCLK1,LGI1,PDE1A,PDE2A,PRMT8,CHRM1,PLEKHB1,TUB,HNRNPK,ARHGAP22,GDAP1L1,ZFYVE9,CAMKV,UBTF,CELF5,PACSIN1,IFFO1,MFSD4A,PTPA,RGS6,MICAL2,OSBPL3,PLCH2,MAPK8,MASP1,PHYHIP,SPIRE1,TOMM20,LRRTM3,ELMO1,CNIH3,PRDM2,STMN4,SRGAP3,RABGAP1L,TMCC2,KCNJ11,ARNT2,KCNMA1,PEX5,DLG2,HS3ST4,WIPF2,PID1,SLC17A6,PLEKHB2,FAM66C,ATG16L1,RAP1GAP,DTNA,PAK5,ABCC9,NUP214,RFX4,JMJD1C,ZNF248,GPR61,TMEM100,PRRT4,RASGRP2" MicroRNA hsa-miR-19a:mirSVR_highEffct hsa-miR-19a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.53E-42 1.91E-38 1.47E-40 1.34E-39 105 1606 "PRR5L,MDM4,CSMD3,F3,CLIP1,RTN1,WAC,GRAMD1B,GPR158,TESK2,SCN3A,MOG,SOX6,CDC42BPA,ITSN1,ANXA7,SH3GL2,DOCK10,SYBU,NLGN1,SHTN1,MIER1,BCO1,RUFY2,MSRA,CCDC88A,SLC14A1,SPHKAP,CAPRIN2,RCOR3,SNAP25,ATP1A2,GABBR1,USP33,SON,MYT1L,SOX5,CAB39,GAD2,NAP1L2,SPART,NDUFA5,SMOC1,RGL1,NEUROD1,FAM168A,GLS,KAZN,CAMTA1,CAMSAP2,PRUNE2,TCF12,SYT6,OMG,TGFBR3,MFSD2A,INA,TLL2,ZFP91,PDE1C,PDE3B,TUB,TMEFF2,ZFYVE9,NRXN1,CCSER2,BTF3L4,ACBD5,POU3F2,PPP3CB,KCNT2,MICAL2,ATRNL1,CHD5,PRKACB,PLPP4,PSD,ANKS1B,PLPPR5,ZNF385B,PLPPR1,PMEPA1,CEP170,MAGI2,ZC3H11A,KCNA4,PTPRD,KCNK2,PCDH15,TMEM255A,ATG16L1,DSCAM,FAM13C,DTNA,PAK5,ABCC9,RET,RFX4,INSYN2,SEC61A2,RPRD1A,ARHGAP12,CBLN2,ELAVL4,OLIG2" MicroRNA hsa-miR-4271:mirSVR_highEffct hsa-miR-4271:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.54E-42 1.92E-38 1.47E-40 1.34E-39 87 1071 "ASIC1,ACLY,CNTNAP3,LGR4,RTKN,RXRG,SNX32,TESK2,LINC00461,FHL1,ELMOD1,PI16,ITSN1,ST3GAL3,ZNF365,MIER1,RUFY2,ARFGAP2,ASPH,GABBR1,SON,WDTC1,KIF21B,JPH4,B4GALNT1,ARPP21,TTLL9,TTC9B,NFASC,C11orf87,NCDN,GANAB,SEPT3,DDHD2,PCDHGA3,VXN,NUMA1,GRIK3,AIFM1,CELF3,REPS2,IGSF21,SEZ6L,ZNF384,PRMT8,BEST3,PLEKHB1,CASC2,TJP2,FADS2,ST8SIA5,CELF5,BEST1,IFFO1,ACBD5,CP,SF1,RNF14,SNCAIP,CSF3R,RBPJ,PRKACB,DZIP3,PRKCG,MAPK10,PUM1,PHYHIP,GON4L,PTHLH,CSDE1,KCNJ10,KCNMA1,RAD52,DPP6,SLC25A18,RASGRF1,CAMK1G,NUP214,JMJD1C,FAM135B,PHC2,ZNF248,VANGL2,PIANP,EFNA3,BSCL2,PRRT4" MicroRNA hsa-miR-320e:mirSVR_lowEffct hsa-miR-320e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-42 1.99E-38 1.51E-40 1.38E-39 115 1936 "MBP,SYT9,LGR4,EYA1,MRVI1,ATAT1,ARID1A,CSMD3,ADAR,CLIP1,AMER2,FCGR1A,SEMA6A,BCAR3,MOG,SFPQ,APC,CCDC80,GPAM,TACC2,SHTN1,MIER1,SFMBT2,LRRC55,PKNOX2,ARHGAP5,SLC8A2,SLCO1A2,NAXD,CAPRIN2,BRINP2,ASTN1,KBTBD12,TMEM108,USP33,MYT1L,NMNAT2,DNER,NAP1L2,NFASC,NCAM1,LMO3,C11orf87,ALDH1L1,ZNF302,SMOC1,GFAP,NCDN,NEUROD1,GANAB,SEPT3,VAMP1,ZNF638,DCLK2,CNTN2,DDR1,PTBP2,CAMK2A,AKNA,GRIA2,GRIN1,GPR88,OPCML,CDC42,PCDH9,CDH10,DCLK1,RBFOX2,IGFN1,PIRT,HMGB1,NLGN3,OPALIN,CNTN1,MEAF6,SLC36A4,FAAP20,CHD1L,FEZ1,MICAL2,ATRNL1,DZIP3,PLPP4,USP54,FAM131B,MASP1,PSMD13,PLPPR1,PTHLH,PRTFDC1,ZC3H11A,PTPRD,KCNA6,PTPRO,KCNJ10,PCDH15,KCNMA1,HS3ST4,RAB5B,TMEM255A,PARP11,FAM57B,RAP1GAP,RASGRF1,DTNA,CAMK1G,JMJD1C,ZNF248,SSPN,SLC4A10,ELAVL4,YY1AP1,BSCL2,EPB41,EPB41L2" MicroRNA hsa-miR-628-5p:mirSVR_lowEffct hsa-miR-628-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.73E-42 2.02E-38 1.52E-40 1.40E-39 106 1639 "SYT9,PAQR6,ARID1A,KCNIP2,CSMD3,DSCAML1,WAC,NLGN4X,SNX32,ASIC4,ELMOD1,ASRGL1,PPFIA1,ITSN1,DGKZ,API5,AQP4,RPH3A,LRRC55,DACH2,SCMH1,ASPH,SLN,ASTN1,KBTBD12,IGSF9B,ATM,ATP1A2,SCN3B,ZCCHC24,KIF21B,SALL3,FXYD6,RAP1GAP2,SPART,DCAF5,PHLDB1,GNAS,UNC5D,ADGRL3,GPM6A,ATF7,DIRAS1,GRIA1,GRIA2,GRID1,GRIK2,GRIK3,GRM3,VWCE,OPCML,LEFTY2,TJP1,AIFM1,ZFP91,CDC42,PCDH8,DCLK1,TPM3,PDE1A,HERC2P3,FTO,PRRX1,PPP2R5C,SNCAIP,FEZ2,MICAL2,ATRNL1,PRKACB,DZIP3,USP54,CTNND2,NRSN1,MAPK8,FGFR1OP2,MASP1,ZBTB16,SPIRE1,PLPPR5,PLPPR1,JAKMIP2,BDNF-AS,ELMO1,STMN4,OCIAD1,PTPRE,PTPRZ1,SRGAP3,AK5,RABGAP1L,KCNK2,PCDH15,DLG2,C12orf4,SLC25A18,DTNA,NUP214,RET,FAM135B,PHC2,ZNF248,SEC61A2,SFXN5,RPRD1A,YY1AP1,BSCL2" MicroRNA hsa-miR-589:mirSVR_lowEffct hsa-miR-589:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.04E-42 2.73E-38 2.04E-40 1.87E-39 103 1549 "ABAT,ADGRV1,CSMD2,ADAR,F3,PLEKHG5,ADCY2,SCN3A,SEMA6A,MOG,SOX6,AMPH,ERICH3,ITSN1,ANXA7,APBB1,MAGI3,CACHD1,JAKMIP3,SHTN1,RUFY2,ARFGAP2,DNAH17,CAPRIN2,MTR,IGSF9B,CCDC181,ATP2B2,GABBR1,SCN3B,SON,GAD2,SALL3,DNER,NFASC,GFAP,KIRREL3,ADHFE1,C1QC,LUZP2,DCLK2,KAZN,CAMTA1,NODAL,UNC5D,KLHL4,GPM6B,ATF7,CACNA1E,GPR19,GRIA1,GRIA2,GRIA4,SPX,TMEM257,NEURL1,MAEL,PADI2,RBFOX2,MAGI1,PDE2A,BEST3,ADGRG1,ANO5,CHRM1,GDAP1L1,KIAA1549L,DNAJC12,MEAF6,NSD2,ACBD5,POU3F2,PRKAB2,CMTM5,PRKCZ,USP54,IGSF1,CTNND2,ECE2,MASP1,PTCH1,CADM2,PRDM2,CSDE1,PTPRD,PTPRE,KCNJ10,KCNK1,KCNK2,PCDH15,DLG2,NKAIN1,HS3ST4,PARP11,ATG16L1,SLC6A15,USH1C,RFX4,SYT15,RAVER2,C2orf80,EN2,TMEM100" MicroRNA hsa-miR-139-5p:mirSVR_lowEffct hsa-miR-139-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.25E-42 2.84E-38 2.11E-40 1.93E-39 112 1842 "LGR4,DUSP27,ARID1A,CSMD3,RTN1,GALNT13,SCN4B,LINC00461,FHL1,BBOX1,UNC79,FOXG1,SELL,SFPQ,ANK1,ANK3,ITSN1,APC,NTNG1,TACC2,JAKMIP3,SHTN1,SLC1A6,ARFGAP2,SCG3,CAPRIN2,SORCS3,RCOR3,B3GAT1,ATP2B2,SON,MYT1L,EMC1,LMO3,C11orf87,CLASP2,FGF17,ADHFE1,NEUROD1,SEPT3,NFIA,DDHD2,CAMSAP2,UNC5D,GOLGB1,GPM6B,TCF7L2,GPR19,NUDT21,GRIA2,GRIA4,GRID1,GRM3,VWCE,TGFBR3,FBXL16,INA,ZFP91,CD81,MAEL,TNS1,CDH8,CDH10,LGI1,HMGB1,CA14,SLC25A27,PRRX1,FAT3,CP,POU3F2,ETNPPL,MED1,CRLS1,PPP2R5C,SNCAIP,TENM4,MICAL2,PHACTR3,PRKACB,DZIP3,FMN2,KIAA1755,PLPP4,MAPK10,DPYSL5,GON4L,PLPPR5,LRRTM3,PLPPR1,PTHLH,CADM2,RGMA,MAGI2,ZC3H11A,KCNA1,KCNA4,PTPRO,RABGAP1L,CCDC3,KIF2A,HS3ST4,DNM2,DPP6,FAM13C,RET,RGS7,VANGL2,SSPN,GPR61,ABI2,TMEM100" MicroRNA hsa-miR-3174:mirSVR_lowEffct hsa-miR-3174:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.15E-42 3.33E-38 2.45E-40 2.25E-39 105 1616 "SERPINA3,LOC100128239,ACER3,SYT9,SLC25A25,ADAR,ADCY2,PNMA8B,SORCS1,TUBB4A,SLC44A5,FCGR1A,FHL1,UNC79,MOG,ANK2,ITSN1,DGKZ,GPAM,AQP4,LRRC55,CSPG5,SMARCE1,SNAP25,ATP1A2,ATP2B2,MEGF11,JPH4,B4GALNT1,SALL3,TTLL9,DNER,NCAM1,LMO3,C11orf87,ZNF638,NHLH1,CAMTA1,CDK5R2,ADGRL3,TMEM136,CACNB2,CAMK2G,VXN,GRIK2,OPCML,TMEM25,P2RX7,TJP1,CELF3,TMEM257,ZDHHC22,KCNK10,PAX6,REPS2,CDC42,PCDH9,RBFOX2,TPM3,PCSK2,TMEFF2,JAM2,GDAP1L1,KIAA1549L,PIK3CD,CPT1C,VAV2,CNTN1,SLC25A27,SLC36A4,MFSD4A,MED1,CRMP1,SNCAIP,PPP3CB,NCAN,RBPJ,DOCK7,IGSF1,NOS1AP,KIAA0408,TOX,SPIRE1,ZNF385B,ITGAV,HP1BP3,PTPRD,KCNA6,KCNK1,DLG2,NKAIN1,WIPF2,PID1,FAM66C,ATG16L1,DBX2,DTNA,RET,ZNF248,PIANP,RBM12,LPAR6,CBLN2,SLC4A10,ELAVL4" MicroRNA hsa-miR-519e:mirSVR_lowEffct hsa-miR-519e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.27E-42 3.40E-38 2.48E-40 2.27E-39 95 1308 "LDLRAD3,CSMD3,ADCY2,GALNT13,DRAXIN,HOGA1,KIAA1109,FGF1,SLC30A10,PKP4,APBB1,APC,MAGI3,SHTN1,PAAF1,MSR1,LRRC55,ARFGAP2,YPEL4,SLC8A3,PDE8B,NAXD,CAPRIN2,MTR,RCOR3,ADGRA1,NRG3,PHYHIPL,SCN3B,USP33,TNIK,CAB39,NMNAT2,JPH4,FXYD6,C11orf87,STOX1,DCAF5,KIRREL3,MLC1,FAM69C,TCF7L2,NUDT21,VXN,GRIA1,LINC00839,CRB1,P2RX7,ZFP91,C1orf94,PTGDR2,LGI1,MAGI1,PDYN,BEST3,ASIC3,CASC2,TLX1,HEPACAM,DUSP26,CADM1,TJP2,PMP2,BEST1,SLC36A4,FAT3,PPP3CB,RGS6,FEZ2,FEZ1,MICAL2,DOCK7,IGSF1,EDRF1,DPYSL5,GON4L,TOMM20,PTHLH,PRDM2,CEP170,KCNA1,OCIAD1,PTPRE,NTM,KCNJ11,KCNK2,TMEM255A,RALGDS,GOPC,DSCAM,RTN4,BSDC1,RFX5,SYT15,FGFBP3" MicroRNA hsa-miR-519b-3p:mirSVR_lowEffct hsa-miR-519b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.53E-42 3.53E-38 2.56E-40 2.35E-39 108 1714 "EPS8,MAP6,MAPT,ACTN2,LDLRAD3,SLC25A25,CSMD3,CLIP1,WAC,SORCS1,AMER2,TRIM46,SGIP1,CDC42BPA,MAGI3,GPAM,DGKD,TACC2,JAKMIP3,CLSTN1,MIER1,ARHGAP5,SHANK2,TAGLN3,MTR,SORCS3,SNAP25,TNIK,KIF21B,IDI2-AS1,GART,DNER,NAP1L2,NFASC,BCL2L2,NDUFA5,AJAP1,NFIA,MLC1,NHLH1,UNC5D,BTRC,TMEM136,GPM6A,FAM69C,CACNA1E,ZEB1,AZIN2,NUDT21,CAMK2G,SYT6,GRIA1,CRB1,MFSD2A,GUCY1A1,ZFP91,KCNK10,PAX6,REPS2,PTGDR2,LGI1,PFKFB3,CASC2,TUB,MS4A7,DUSP26,CELF5,PRRX1,IFFO1,CNRIP1,MFSD4A,MED1,PNKD,KCNT2,FEZ2,ATRNL1,PRKCZ,NOS1AP,SYNC,PRDM2,HP1BP3,CEP170,ZC3H11A,KCNA1,OCIAD1,PTPRD,KCNA6,PTPRE,SRGAP3,PCDH15,NAV2,DLG2,HS3ST4,C12orf4,SLC25A18,ABI1,GOPC,FAM13C,DTNA,PAK5,BSDC1,SFXN5,SLC39A12,RPRD1A,BSCL2,C2orf80,TMEM100,EPB41L1" MicroRNA hsa-miR-1178:mirSVR_lowEffct hsa-miR-1178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.88E-42 3.72E-38 2.68E-40 2.46E-39 105 1618 "MAG,LOC100128239,SYT9,RTN3,EYA1,KLHL32,ADCY2,WAC,ERMN,FCGR1B,TOMM40L,HOGA1,AGT,LRRC7,FHL1,TRIM46,ANK2,PPFIA1,DOCK10,PAAF1,LGI3,DKK3,SOX5,ZSWIM8,AHCYL1,B4GALNT1,KIF1B,DNER,SPART,ZNF302,INKA2,NEUROD1,AJAP1,NFIA,ARHGEF7,NHLH1,OS9,ASTN2,KAZN,CAMTA1,NODAL,UNC5D,ADGRL3,ANO4,GPM6B,FAM69C,ZEB1,NUDT21,VSTM2A,BRSK2,LINC00839,PTPN5,TJP1,AIFM1,ZFP91,CDK11B,CDH8,PDE2A,NTSR2,HERC2P3,CCSER2,FTO,COL9A2,CNRIP1,MED1,RGS6,RBPJ,PRKACB,DZIP3,ARHGEF4,IGSF1,ZBTB16,ANKS1B,TOMM20,PSMD13,DNAJC6,CA10,JAKMIP2,BDNF-AS,MED24,BLOC1S6,KCNA4,KCNA6,SMG7,PTPRO,C1orf109,SRGAP3,RABGAP1L,TMCC2,PEX5,DLG2,HS3ST4,WIPF2,TMEM255A,DNM2,C12orf4,RAP1GAP,RASGRF1,DTNA,CAMK1G,RGS7,FAM135B,ZNF248,CBLN2,RCAN2" MicroRNA hsa-miR-2115:mirSVR_lowEffct hsa-miR-2115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.11E-42 4.39E-38 3.14E-40 2.88E-39 114 1918 "EPS8,MBP,SYT9,LDLRAD3,GALNT13,ADD3,SORCS1,ADORA1,AMER2,FOXRED2,NLGN4X,KIAA1109,ASIC4,FOXG1,PDZD4,ERICH3,NTNG1,SLITRK3,RUFY2,ARFGAP2,YPEL4,ASCL1,NAXD,CAPRIN2,KBTBD12,B3GAT1,TMEM151A,MEGF11,USP33,KIF21B,ZSWIM8,KIF1B,SPART,COLGALT2,NFIA,GLS,BTRC,ANO4,CACNA1A,GPM6B,ATF7,CACNA1E,ZEB1,PTBP2,VXN,GRIA2,RFFL,TMEM25,TMEM9,CELF3,KCNK10,DAAM2,TNFRSF1B,PCDH9,DCLK1,ARHGAP19,PIRT,CHGA,PFKFB3,MS4A7,NLGN3,ZFYVE9,A2ML1,CCSER2,TJP2,FTO,SULT4A1,BEST1,SLC36A4,FAT3,CRLS1,KCNT2,PRKAB2,PRKACB,DZIP3,ARHGEF4,MAPK10,NOS1AP,KIAA0408,BRINP3,ZBTB16,TOX,WBP1L,SPIRE1,PLPPR5,ZNF385B,ITGAV,MAGI2,STMN4,KCNA1,PTPRD,AK5,RABGAP1L,TMCC2,KCNJ11,CCDC3,NAV2,WIPF2,SLC25A48,PLEKHB2,SLC25A18,RAP1GAP,SUSD4,DBX2,DTNA,BSDC1,SLC6A15,NUP214,RGS7,RGS10,RNF220,SH3GLB1,VWA5A,BAALC" MicroRNA hsa-miR-219-1-3p:mirSVR_lowEffct hsa-miR-219-1-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.80E-42 4.76E-38 3.38E-40 3.10E-39 107 1687 "TTYH1,EPS8,APC2,MBP,RTN3,SYNDIG1,ACTN2,ADGRV1,CSMD2,ARID1A,MDM4,KLRC4,GALNT13,SCN3A,BBOX1,SLC30A10,SOX6,TRIM46,AMPH,ANK3,ITSN1,NLGN1,ST3GAL3,MADD,ARHGAP5,SLC14A1,DACH2,CSPG5,TAGLN3,SLN,ATP2B2,DKK3,SCN3B,TNIK,NMNAT2,ARPP21,KIF1B,COLGALT2,ALDH1L1,ERBIN,NFIA,NHLH1,KAZN,CAMSAP2,CNTN2,GOLGB1,CACNA1A,WSCD1,GPM6A,TCF7L2,PTBP2,VXN,GRIA2,GRIA4,OPCML,CRB1,P2RX7,ZDHHC22,PADI2,CDH8,HMGB1,PFKFB3,CASC2,GDAP1L1,KIAA1549L,PIK3CD,CCSER2,TJP2,PMP2,BEST1,P2RY12,FAT3,CNRIP1,CRMP1,CRLS1,SNCAIP,KCNT2,ATRNL1,PHACTR3,PRKACB,PRKCZ,USP54,NOS1AP,PROX1,MASP1,GON4L,SYNC,LRRTM3,BDNF-AS,PRDM2,CEP170,OCIAD1,KCNH1,AK5,RABGAP1L,KCNJ10,WIPF2,PID1,RASGRF1,BSDC1,SLC6A15,FAM135B,PIANP,RPRD1A,FGFBP3,TMEM100,LRRC23" MicroRNA hsa-miR-30e:mirSVR_highEffct hsa-miR-30e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-41 5.52E-38 3.89E-40 3.56E-39 116 1991 "MAP6,CDHR1,MBP,SYT9,RCSD1,ARID1A,CSMD3,GALNT13,CDC7,FABP7,SORCS1,ERMN,SCN3A,LINC00461,SLC30A10,MOBP,FOXG1,ERICH3,ITSN1,DOCK10,APC,MAGI3,SORBS1,CACHD1,NLGN1,JAKMIP3,PAAF1,ZNF365,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,SMARCE1,RCOR3,NRG3,ATP2B2,SON,ILDR2,JPH4,KIF1B,NAP1L2,NPAS3,SPART,CLASP2,ERBIN,RGL1,ADHFE1,GLS,SYT4,GNAS,DDHD2,CAMTA1,ADGRL3,ANO4,PRUNE2,GPM6A,CACNB2,GPR19,EML4,CECR2,GRIA2,RFFL,GRM3,OMG,CRB1,USP2,TLL2,CELF3,PCDH9,LGI1,MAGI1,PIRT,ZMYND8,ANO5,MS4A7,ZBED5,NEGR1,PIK3CD,MICAL1,ACBD5,PNKD,OSBPL3,PHACTR3,PRKACB,DOCK7,CTNND2,TOX,SPIRE1,TOMM20,LRRTM3,CA10,JAKMIP2,PMEPA1,CEP170,CSDE1,MAGI2,BLOC1S6,KCNA2,PLPPR4,RABGAP1L,KCNMA1,PARP11,RALGDS,PAK5,ABCC9,RGS7,FAM135B,TTLL7,RNF220,RPRD1A,RAVER2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-10a*:mirSVR_lowEffct hsa-miR-10a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-41 5.75E-38 4.02E-40 3.69E-39 109 1756 "LOC100128239,ACER3,CNTNAP3,SYT9,LGR4,ADGRV1,WLS,CSMD3,ADD3,CDC7,ELMOD1,SFPQ,ANXA7,MAGI3,TACC2,CACHD1,NLGN1,MIER1,MSRA,CCDC88A,ASCL1,ASPH,SMARCE1,SNAP25,CCDC181,EIF4G3,SON,MYT1L,B3GALT2,TNIK,ILDR2,AHCYL1,ENKUR,NAP1L2,SPART,C11orf87,CLASP2,STOX1,DCAF5,NEUROD1,SLCO1C1,NFIA,ZNF638,NKX2-2,CAMSAP2,ANO4,GPM6B,CECR2,VSTM2A,GRIA4,OLR1,TGFBR3,USP2,TMEM257,PAX6,HPS5,MAGI1,ZNF384,PRMT8,PDE4B,CCSER2,FADS2,DNAJC12,CELF5,NXPH1,CRLS1,PPP2R5C,PPP3CB,FEZ1,ATRNL1,VCAN,PHACTR3,DOCK7,DZIP3,FMN2,RAB39A,USP54,FGFR1OP2,KLK6,ANKS1B,TUBB2B,LRRTM3,PTCH1,PLPPR1,PTHLH,CADM2,ELMO1,PRTFDC1,CEP170,MAGI2,OCIAD1,PTPRD,PTPRZ1,KCNK2,OLIG1,SLC17A6,FAM13C,DTNA,SLC6A15,FAM135B,ATL1,RLBP1,SLC39A12,SSPN,RBM12,LMO1,RERGL,ARHGAP12,UEVLD" MicroRNA hsa-miR-466:mirSVR_highEffct hsa-miR-466:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-41 5.91E-38 4.10E-40 3.77E-39 114 1924 "RABEPK,EPS8,PRR5L,MAPT,LDLRAD3,WLS,KLHL32,FABP7,ERMN,GPR158,LRRTM4,FOXG1,AMPH,ERICH3,ANK2,ANK3,USP28,ITSN1,DOCK10,SESN3,NTNG1,SYBU,API5,MIER1,ARHGAP5,CCDC88A,SLC14A1,ASCL1,BRINP2,RCOR3,PALLD,MEGF11,USP33,SON,WDTC1,MYT1L,ZCCHC24,GAD2,NPAS3,ERBIN,RGL1,SLCO1C1,ARHGEF7,GLS,RHBDL3,PCDH11X,ZNF638,SYT4,CAMSAP2,ADGRL3,KLHL4,ANO4,GPM6A,TCF7L2,ZEB1,NRDC,EML4,CECR2,GRIA2,GRID1,RFFL,GRM3,P2RX7,PCDH8,PCDH9,LGI1,PCSK2,PDE3B,PDE4B,CIART,ANO5,MS4A7,TMEFF2,UBTF,PRRX1,CNRIP1,KCNT2,OSBPL3,ATRNL1,VCAN,DZIP3,FMN2,PKN2,NRSN1,PUM1,PROX1,WBP1L,SYTL2,GON4L,PTCH1,JAKMIP2,LRP8,CEP170,KCNA2,PTPRD,C1orf109,SV2A,ARNT2,KCNK1,PEX5,WIPF2,PARP11,DPP6,RALGDS,RTN4,ABCC9,JMJD1C,ARHGEF10L,ZNF248,SSPN,RBM12,CBLN2,SLC4A10,OLIG2" MicroRNA hsa-miR-218:PITA hsa-miR-218:PITA_TOP PITA 1.16E-41 6.30E-38 4.32E-40 3.97E-39 63 506 "EPS8,ASIC1,LGR4,RTN3,MRVI1,CSMD3,GALNT13,LRRC7,SEMA6A,PKP4,SHTN1,SLC1A2,ARHGAP5,CCDC88A,B3GAT1,TMEM151A,MYT1L,SOX5,KIF21B,LMO3,GLS,GNAS,GNG3,ANO4,TBX15,GPM6A,TCF12,PSD3,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,GUCY1A2,ZFP91,PCDH8,DCLK1,TPD52,TUB,NRXN1,NMT2,FAT3,RIMS4,PLD5,CTNND2,PUM1,TOX,RIMS3,CADM2,ELMO1,MAGI2,SMG7,SV2A,DLG2,CAB39L,KIF2A,SLC17A6,RTN4,ZYG11B,RET,INSYN2,RNF220,EPB41L1" MicroRNA hsa-miR-135a:mirSVR_lowEffct hsa-miR-135a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-41 6.50E-38 4.32E-40 3.97E-39 113 1892 "DPF1,SERPINA3,ACER3,APC2,ADARB2,KLHL32,ADCY2,WAC,SLC44A5,GPR158,LINC00461,PLA2G6,SEMA6A,UNC79,ELMOD1,MOBP,CDC42BPA,ANK1,PPFIA1,ITSN1,APBA2,NLGN1,CLSTN1,SLC1A6,SLC8A2,SHANK2,NSG2,DACH2,CAPRIN2,SLN,SORCS3,RCOR3,ATP2B2,MEGF11,SCN3B,USP33,WDTC1,MYT1L,KIF21B,AHCYL1,NMNAT2,B4GALNT1,SALL3,KIF1B,C11orf87,NEUROD1,PCDH11X,ZNF638,DCLK2,DDHD2,CAMTA1,UNC5D,PRUNE2,CACNA1E,ZEB1,NUDT21,VXN,GRIA2,GRIN1,OMG,SHISA7,TLL2,TNS1,CDH8,RBFOX2,ARHGAP19,LGI1,MAGI1,PDE1A,PDE2A,PRMT8,PDYN,FNDC5,ANO5,CASC2,HNRNPK,JAM2,NEGR1,CCSER2,TJP2,ST8SIA5,PLXNB3,NSD2,FAT3,PNKD,RNF14,SNCAIP,RBPJ,ARHGEF4,TOX,SPIRE1,SYNC,BDNF-AS,PRDM2,CSDE1,PTPRE,KCNC1,NTM,RABGAP1L,DLG2,DNM2,SLC25A18,DTNA,BSDC1,ZYG11B,NUP214,ATL1,TTLL7,SEC61A2,LPAR6,CBLN2,RAVER2,EPB41" MicroRNA hsa-miR-30d-5p:TargetScan hsa-miR-30d-5p TargetScan 1.21E-41 6.53E-38 4.32E-40 3.97E-39 89 1144 "ARID1A,MDM4,CDC7,DRAXIN,SCN3A,FOXG1,CDC42BPA,ITSN1,PPM1E,NTNG1,MAGI3,DGKZ,DGKD,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,DNAH17,C10orf105,B3GAT1,NRG3,FYN,ATP2B2,KIF21B,ILDR2,JPH4,NCAM1,DCAF5,RGL1,NEUROD1,ACSBG1,NFIA,NKX2-2,CNTN2,ANO4,PRUNE2,GPR26,EML4,CECR2,PSD3,GRIA2,RFFL,GRM3,OMG,CELF3,LGI1,PIRT,JAM2,CADM1,NEGR1,PIK3CD,FTO,CELF5,MICAL1,PRRX1,CRMP1,PPP3CB,ATRNL1,CHD5,DOCK7,MAPK8,FAM131B,KIAA0408,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,KCNA4,CDH20,RABGAP1L,KCNN3,RALGDS,FAM13C,DTNA,ABCC9,SEC61A2,RNF220,EFNA3,RBM12,RPRD1A,RAVER2,ELAVL3,ELAVL4,EPB41" MicroRNA hsa-miR-30a-5p:TargetScan hsa-miR-30a-5p TargetScan 1.21E-41 6.53E-38 4.32E-40 3.97E-39 89 1144 "ARID1A,MDM4,CDC7,DRAXIN,SCN3A,FOXG1,CDC42BPA,ITSN1,PPM1E,NTNG1,MAGI3,DGKZ,DGKD,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,DNAH17,C10orf105,B3GAT1,NRG3,FYN,ATP2B2,KIF21B,ILDR2,JPH4,NCAM1,DCAF5,RGL1,NEUROD1,ACSBG1,NFIA,NKX2-2,CNTN2,ANO4,PRUNE2,GPR26,EML4,CECR2,PSD3,GRIA2,RFFL,GRM3,OMG,CELF3,LGI1,PIRT,JAM2,CADM1,NEGR1,PIK3CD,FTO,CELF5,MICAL1,PRRX1,CRMP1,PPP3CB,ATRNL1,CHD5,DOCK7,MAPK8,FAM131B,KIAA0408,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,KCNA4,CDH20,RABGAP1L,KCNN3,RALGDS,FAM13C,DTNA,ABCC9,SEC61A2,RNF220,EFNA3,RBM12,RPRD1A,RAVER2,ELAVL3,ELAVL4,EPB41" MicroRNA hsa-miR-30b-5p:TargetScan hsa-miR-30b-5p TargetScan 1.21E-41 6.53E-38 4.32E-40 3.97E-39 89 1144 "ARID1A,MDM4,CDC7,DRAXIN,SCN3A,FOXG1,CDC42BPA,ITSN1,PPM1E,NTNG1,MAGI3,DGKZ,DGKD,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,DNAH17,C10orf105,B3GAT1,NRG3,FYN,ATP2B2,KIF21B,ILDR2,JPH4,NCAM1,DCAF5,RGL1,NEUROD1,ACSBG1,NFIA,NKX2-2,CNTN2,ANO4,PRUNE2,GPR26,EML4,CECR2,PSD3,GRIA2,RFFL,GRM3,OMG,CELF3,LGI1,PIRT,JAM2,CADM1,NEGR1,PIK3CD,FTO,CELF5,MICAL1,PRRX1,CRMP1,PPP3CB,ATRNL1,CHD5,DOCK7,MAPK8,FAM131B,KIAA0408,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,KCNA4,CDH20,RABGAP1L,KCNN3,RALGDS,FAM13C,DTNA,ABCC9,SEC61A2,RNF220,EFNA3,RBM12,RPRD1A,RAVER2,ELAVL3,ELAVL4,EPB41" MicroRNA hsa-miR-30c-5p:TargetScan hsa-miR-30c-5p TargetScan 1.21E-41 6.53E-38 4.32E-40 3.97E-39 89 1144 "ARID1A,MDM4,CDC7,DRAXIN,SCN3A,FOXG1,CDC42BPA,ITSN1,PPM1E,NTNG1,MAGI3,DGKZ,DGKD,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,DNAH17,C10orf105,B3GAT1,NRG3,FYN,ATP2B2,KIF21B,ILDR2,JPH4,NCAM1,DCAF5,RGL1,NEUROD1,ACSBG1,NFIA,NKX2-2,CNTN2,ANO4,PRUNE2,GPR26,EML4,CECR2,PSD3,GRIA2,RFFL,GRM3,OMG,CELF3,LGI1,PIRT,JAM2,CADM1,NEGR1,PIK3CD,FTO,CELF5,MICAL1,PRRX1,CRMP1,PPP3CB,ATRNL1,CHD5,DOCK7,MAPK8,FAM131B,KIAA0408,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,KCNA4,CDH20,RABGAP1L,KCNN3,RALGDS,FAM13C,DTNA,ABCC9,SEC61A2,RNF220,EFNA3,RBM12,RPRD1A,RAVER2,ELAVL3,ELAVL4,EPB41" MicroRNA hsa-miR-30e-5p:TargetScan hsa-miR-30e-5p TargetScan 1.21E-41 6.53E-38 4.32E-40 3.97E-39 89 1144 "ARID1A,MDM4,CDC7,DRAXIN,SCN3A,FOXG1,CDC42BPA,ITSN1,PPM1E,NTNG1,MAGI3,DGKZ,DGKD,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,DNAH17,C10orf105,B3GAT1,NRG3,FYN,ATP2B2,KIF21B,ILDR2,JPH4,NCAM1,DCAF5,RGL1,NEUROD1,ACSBG1,NFIA,NKX2-2,CNTN2,ANO4,PRUNE2,GPR26,EML4,CECR2,PSD3,GRIA2,RFFL,GRM3,OMG,CELF3,LGI1,PIRT,JAM2,CADM1,NEGR1,PIK3CD,FTO,CELF5,MICAL1,PRRX1,CRMP1,PPP3CB,ATRNL1,CHD5,DOCK7,MAPK8,FAM131B,KIAA0408,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,KCNA4,CDH20,RABGAP1L,KCNN3,RALGDS,FAM13C,DTNA,ABCC9,SEC61A2,RNF220,EFNA3,RBM12,RPRD1A,RAVER2,ELAVL3,ELAVL4,EPB41" MicroRNA hsa-miR-3185:mirSVR_highEffct hsa-miR-3185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-41 6.68E-38 4.39E-40 4.03E-39 94 1289 "SERPINA3,PRR5L,ACLY,MEG3,IL17D,CSMD3,RTN1,DSCAML1,FABP7,SORCS1,FOXRED2,SLC44A5,GPR158,LRRC7,FGF14,CNIH2,ITSN1,MAGI3,PAAF1,ZNF365,MIER1,RUFY2,LRRC55,CADPS,CAPRIN2,RCOR3,DKK3,AHCYL1,JPH4,TTLL9,GART,DNER,NPAS3,LMO3,C11orf87,CLASP2,GLS,NHLH1,GNAS,DDHD2,PSRC1,ANO4,PTBP2,EML4,GRID1,ADAMTS8,GPR88,TF,CCKBR,MFSD2A,TMEM9,IGSF21,TNR,ZNF384,PDE1A,PDE1C,FNDC5,CASC2,GDAP1L1,NRXN1,NRXN2,ANLN,BEST1,PRRX1,CNRIP1,MFSD4A,CRLS1,KIAA1755,PLPP4,PKN2,USP54,CTNND1,MAPK10,TOX,PLPPR5,ZNF385B,ELMO1,LRP8,CEP170,PTPRE,PLPPR4,CCDC3,DLG2,DPP6,RASGRF1,DTNA,ZYG11B,PIANP,LMO1,ELAVL4,EN2,OLIG2,EPB41L2,UEVLD" MicroRNA hsa-miR-4325:mirSVR_lowEffct hsa-miR-4325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-41 7.15E-38 4.68E-40 4.29E-39 99 1441 "LOC100128239,ACER3,CDHR1,TMEM74,MBP,RTN3,CSMD3,FOXRED2,CHST15,SNX32,LINC00461,SEMA6A,BCAR3,FHL1,MOG,ANK2,ITSN1,PKP4,SH3GL2,PPM1E,SESN3,NTNG1,SLITRK3,AQP4,URGCP,CCDC88A,ASPH,SMARCE1,RCOR3,PALLD,SON,ZSWIM8,B4GALNT1,EMC1,IDI2-AS1,KIF1B,FXYD6,ZNF302,RGL1,KIRREL3,ADHFE1,PHLDB1,FAM168A,PCDH11X,GNAS,CAMTA1,GNG4,NODAL,UNC5D,PRUNE2,EML4,CAMK2A,GRIA4,OLR1,LEFTY2,TGFBR3,TJP1,DAAM2,TNS1,PTGDR2,PCSK2,PRMT8,PIRT,HMGB1,SCRG1,ANO5,TLX1,CADM1,NMT2,MEAF6,VCAN,DZIP3,CTNND1,CTNND2,MAPK10,ECE2,TOMM20,PSMD13,ITGAV,CADM2,PRDM2,MAGI2,BLOC1S6,KCNA4,PLPPR4,PTPRO,RABGAP1L,KCNK2,DPP6,GOPC,DTNA,ZYG11B,INSYN2,TTLL7,SFXN5,ABI2,VWA5A,RAVER2,OLIG2" MicroRNA hsa-miR-454:mirSVR_lowEffct hsa-miR-454:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-41 7.81E-38 5.07E-40 4.66E-39 110 1795 "PRR5L,ASIC1,LGR4,LDLRAD3,CSMD2,FCGR1A,CHST15,SCN4B,LINC00461,LRRC7,BCAR3,FOXG1,SELL,ITSN1,DOCK10,TACC2,SHTN1,ZNF365,ARHGAP5,ASCL1,SCG3,RCOR3,ATM,ATP1A2,DKK3,SON,B3GALT2,TNIK,KIF21B,CAB39,EMC1,KIF1B,NAP1L2,NPAS3,NCAM1,C11orf87,NDUFA5,AJAP1,MLC1,VAMP1,SYT4,KAZN,TMEM136,ATF7,ZEB1,AZIN2,CECR2,VSTM2A,NUMA1,GRIA2,GRIA4,OLR1,OPCML,USP2,GUCY1A1,CELF3,ZFP91,KCNK10,HPS5,CDC42,RBFOX2,MAGI1,PDE1A,PDE4B,SCRG1,PFKFB3,CASC2,MS4A7,VAV2,SLC25A27,P2RY12,NSD2,PNKD,PPP3CB,FEZ2,MICAL2,PRKAB2,DOCK7,DZIP3,SPIRE1,LRRTM3,CSDE1,MAGI2,KCNA4,PTPRD,PTPRE,AK5,KCNJ10,KCNK1,SNX27,DLG2,DLG3,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,GNE,FAM13C,DTNA,RTN4,BSDC1,RFX5,JMJD1C,ZNF248,PIANP,SLC4A10,C2orf80,TMEM100,UEVLD" MicroRNA hsa-miR-218:mirSVR_lowEffct hsa-miR-218:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-41 8.23E-38 5.31E-40 4.87E-39 110 1796 "LOC100128239,ASIC1,TMEM74,ATAT1,KLHL32,ADCY2,ERMN,AMER2,LRRTM4,LRRC7,FGF14,SEMA6A,BCAR3,HPCAL4,MOBP,SGIP1,CDC42BPA,ANK3,PPFIA1,DOCK10,MAGI3,GPAM,SLITRK3,SORBS1,LRRC4C,API5,USP16,RUFY2,ARHGAP5,SLC8A2,SLC8A3,NSG2,CGREF1,GPR153,CSPG5,SLCO1A2,TMEM151A,SNCB,ATP1A2,NRG3,PALLD,TNIK,KIF21B,ZSWIM8,NMNAT2,KIRREL3,NFIA,ARHGEF7,GLS,RHBDL3,PCDH11X,SEMA4A,GNG3,UNC5D,ADGRL3,TMEM136,TBX15,VWC2,CACNB2,NRGN,TF,TMEM25,GUCY1A1,ZFP91,PAX6,CDH10,MAGI1,PDE4B,FNDC5,BEST3,CASC2,TUB,DUSP26,GDAP1L1,CCSER2,BEST1,BTF3L4,IFFO1,FAT3,CNRIP1,PPP3CB,MICAL2,OSBPL3,NCAN,RBPJ,KIAA0408,LRRTM3,BDNF-AS,PRDM2,PRTFDC1,HP1BP3,BLOC1S6,ZC3H11A,KCNA6,SMG7,NTM,KCNK2,PCDH15,KCNN3,WIPF2,DPP6,C12orf4,RAP1GAP,DTNA,RET,FAM135B,SSPN,RAVER2,EPB41L1,BAALC" MicroRNA hsa-miR-449b*:mirSVR_lowEffct hsa-miR-449b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-41 8.66E-38 5.55E-40 5.09E-39 110 1797 "EMID1,CNTNAP3,WLS,CSMD3,ADAR,RTN1,WAC,SORCS1,GRAMD1B,TOMM40L,SCN3A,FGF1,MOBP,ANK1,ANK2,APBA2,APBB1,DGKZ,SHTN1,SLC2A5,RUFY2,MSRA,ARHGAP5,SLC8A3,MT3,SLCO1A2,DDX25,MTR,B3GAT1,GABBR1,WDTC1,CAB39,GAD2,ZSWIM8,JPH4,B4GALNT1,ADAM15,KIF1B,NPAS3,NASP,SPART,C11orf87,BCL2L2,RCOR2,NELL1,SEPT3,MLC1,ARHGEF7,NHLH1,OS9,SYT4,DCLK2,UNC5D,MMD2,WWC1,GPM6B,GPR17,AZIN2,TMEM151B,GRIA2,CYB561A3,LINC00839,CRB1,TMEM25,MFSD2A,TLL2,HPS5,ARHGAP19,PRMT8,DLGAP3,CCSER2,OPALIN,FTO,SULT4A1,BEST1,FAAP20,CHD1L,CRLS1,SNCAIP,KCNT2,MICAL2,ATRNL1,CMTM5,PKN2,ARHGEF4,NRSN1,EDRF1,TOX,WBP1L,SPIRE1,BDNF-AS,PRDM2,COPS7A,OLFM3,PTPRD,PTPRO,SRGAP3,DLG2,DLG3,HS3ST4,ATG16L1,ATN1,DTNA,CAMK1G,ARHGEF10L,SYT15,RBM12,CBLN2,EPB41,BAALC" MicroRNA hsa-miR-454:mirSVR_highEffct hsa-miR-454:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.66E-41 8.97E-38 5.70E-40 5.23E-39 103 1570 "RABEPK,SDE2,CNTNAP3,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,WAC,GPR158,TESK2,SCN3A,MOG,SOX6,ERICH3,SGIP1,USP28,APBB1,APC,SLITRK3,SYBU,API5,AQP4,MIER1,BCO1,RUFY2,YPEL4,CCDC88A,SHANK2,SLC14A1,NAXD,CAPRIN2,MTR,SNAP25,NRG3,USP33,MYT1L,SOX5,B4GALNT1,TTLL9,DNER,SPART,SMOC1,ERBIN,NEUROD1,NFIA,GLS,CAMTA1,CAMSAP2,PRUNE2,WSCD1,GPM6A,CAMK2A,SYT6,GPR88,OMG,LINC00839,TGFBR3,TNFRSF1B,TNS1,PCDH9,PDE1C,PDE3B,ANO5,ZFYVE9,KIAA1549L,CCSER2,TJP2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CRLS1,RGS6,CHD5,FMN2,USP54,ARHGEF4,NRSN1,FGFR1OP2,PSD,PLPPR1,PMEPA1,PTHLH,PRDM2,LRP8,CEP170,PCDH15,KCNN3,CAB39L,RAB5B,PID1,ATG16L1,C12orf4,ABCC9,RET,SEC61A2,SLC39A12,RBM12,RPRD1A,ARHGAP12" MicroRNA hsa-miR-18b:mirSVR_lowEffct hsa-miR-18b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.67E-41 9.04E-38 5.70E-40 5.23E-39 104 1602 "F3,ADARB2,CLIP1,KLHL32,GALNT13,TUBB4A,FOXRED2,CHST15,SCN4B,SEMA6A,TRIM46,ERICH3,ANK2,PPFIA1,GPAM,JAKMIP3,CLSTN1,LRRC55,ARHGAP5,CCDC88A,DACH2,SCG3,ARFGAP1,TAGLN3,NAXD,ASTN1,IGSF9B,NRG3,EIF4G3,PALLD,WDTC1,ZCCHC24,ZSWIM8,NEK6,ADGRB2,DNER,FXYD6,NCAM1,CLASP2,ALDH1L1,NEUROD1,GLS,C1QC,CAMSAP2,MYRF,KLHL4,CACNB2,LILRA1,TCF7L2,PTBP2,CAMK2G,NUMA1,GRIA2,GRIA4,GRIK3,OLR1,CRB1,TMEM25,TGFBR3,NEURL1,PAX6,TNS1,PCDH9,PTGDR2,RBFOX2,TPM3,MAGI1,HMGB1,SULT4A1,C11orf49,MFSD4A,CP,SNCAIP,TENM4,RBPJ,PLPP4,IGSF1,CTNND2,KIAA0513,WBP1L,PLPPR5,BDNF-AS,PTHLH,CNIH3,RGMA,CSDE1,BLOC1S6,KCNA1,PTPRE,PTPRO,PTPRZ1,SRGAP3,RAB5B,PID1,PARP11,ABCC9,USH1C,RGS7,PHC2,TTLL7,VWA5A,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-541*:mirSVR_highEffct hsa-miR-541*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-41 9.07E-38 5.70E-40 5.23E-39 99 1445 "ACER3,ACTN2,MDM4,RTN1,GALNT13,ERMN,ADORA3,KIAA1109,LRRC7,FGF14,MOG,SELL,ANK2,ANK3,SH3GL2,PPM1E,DOCK10,MAGI3,JAKMIP3,API5,ZNF365,RUFY2,MSR1,DACH2,SCG3,CAPRIN2,ASPH,SMARCE1,ATM,NRG3,DKK3,ZCCHC24,AHCYL1,ENKUR,TTLL9,NAP1L2,DCAF5,NELL1,GLS,ZNF638,GNAS,DDHD2,CAMSAP2,UNC5D,TBX15,GPM6A,VWC2,TCF12,GRIA4,GRID1,GRIK4,TJP1,PAH,PAX6,PCDH9,LGI1,TPM3,PDE1C,CIART,BEST3,JAM2,GDAP1L1,SPATA6,SLC36A4,ACBD5,PNKD,CHD5,VCAN,NCAN,FMN2,PLD5,CTNND1,FGFR1OP2,TOX,ANKS1B,LRRTM3,PTHLH,PRDM2,CEP170,STMN4,PTPRE,AK5,KCNK1,PCDH15,KCNN3,KIF2A,HS3ST4,TMEM255A,FAM66C,C12orf4,DBX2,DTNA,CAMK1G,SFXN5,ABI2,VWA5A,CBLN2,UEVLD,BAALC" MicroRNA hsa-miR-1915:mirSVR_lowEffct hsa-miR-1915:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-41 9.19E-38 5.74E-40 5.27E-39 108 1732 "TTYH1,ACTN2,MEG3,FAM43B,MRVI1,ATAT1,CSMD2,NDRG2,WAC,CDC7,PNMA8B,ERMN,DISP3,SLC30A10,HPCAL4,TRIM46,ERICH3,CNIH2,BCAN,SORBS1,JAKMIP3,BCAS1,RPH3A,MADD,PKNOX2,ARFGAP2,SLC8A2,YPEL4,SLC8A3,CGREF1,SORCS3,C10orf105,IGSF9B,TMEM151A,ATP1A3,GABBR1,JPH4,B4GALNT1,ADAM15,SMOC1,HEPN1,GANAB,NODAL,MYRF,TMEM136,NEU4,PTBP2,CAMK2A,PCDHGA3,SYT6,NUMA1,GRIA1,GPR88,CYB561A3,LINC00839,LEFTY2,MFSD2A,FBXL16,ZDHHC22,ZFP91,TNFRSF1B,GPR37L1,HAPLN2,PFKFB3,PLEKHB1,CASC2,TLX1,JAM2,DUSP26,NLGN3,NRXN2,PLXNB3,NSD2,FAT3,SNCAIP,PPP3CB,MICAL2,RIMS4,PLPP4,CTNND1,MAPK10,PUM1,ECE2,MASP1,ZBTB16,GON4L,COPS7A,MAGI2,OCIAD1,KCNC1,SV2A,KCNMA1,DLG3,NKAIN1,OLIG1,RAB5B,FAM57B,GNE,DTNA,ZYG11B,NUP214,PHC2,EFNA3,RPRD1A,RAVER2,PRRT4,SEZ6,BAALC" MicroRNA hsa-miR-193a-3p:mirSVR_lowEffct hsa-miR-193a-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-41 1.08E-37 6.71E-40 6.16E-39 93 1267 "ZFYVE27,ACER3,ASIC1,ACHE,SYT9,ADGRV1,IL17D,RTKN,CLIP1,SORCS1,HOGA1,TESK2,DISP3,FHL1,UNC79,SEMA6C,CDC42BPA,ANK3,ITSN1,APC,MAGI3,CCDC80,NLGN1,BCAS1,CLSTN1,ZNF365,RUFY2,LRRC55,YPEL4,NSG2,SORCS3,EIF4G3,GABBR1,SOX5,ZSWIM8,NPAS3,NFASC,NCAM1,CLASP2,BCL2L2,SLCO1C1,C1QC,NODAL,CNTN2,TMEM136,TBX15,NUDT21,NUMA1,GRIA4,RFFL,OMG,CRB1,TGFBR3,DAAM2,MAEL,PCDH9,PCSK2,FNDC5,HMGB1,LRTM2,CASC2,KIAA1549L,CAMKV,CCSER2,TJP2,C11orf49,NXPH1,CHD1L,FEZ1,PRKACB,PRKCZ,NRSN1,FAM131B,ECE2,NOS1AP,ZNF385B,PTCH1,RGMA,CSDE1,PTPRE,KCNJ9,KCNJ10,KCNMA1,PID1,FAM66C,ZYG11B,RBM12,GPR61,ABI2,BSCL2,C2orf80,EN2,EPB41" MicroRNA hsa-miR-1910:mirSVR_lowEffct hsa-miR-1910:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.02E-41 1.10E-37 6.77E-40 6.21E-39 111 1835 "ZFYVE27,MAPT,RBM10,MBP,SYT9,RTN3,RTKN,MDM4,CSMD3,GALNT13,FABP7,PNMA8B,SLC44A5,TESK2,SCN4B,ASIC4,FHL1,SOX6,TRIM46,PI16,CNIH2,PKP4,APBB1,MAGI3,ZCCHC17,SFMBT2,LRRC55,DACH2,GPR153,ASPH,DKK3,SCN3B,SOX5,NMNAT2,JPH4,ARPP21,EMC1,ADAM15,KIF1B,ADGRB2,C11orf87,SMOC1,GFAP,INKA2,FGF17,PCDH11X,DCLK2,CNTN2,ACSL6,HAP1,CAMK2G,CECR2,VXN,NUMA1,PSD3,GRIA1,CYB561A3,SHISA7,CCKBR,PAX6,TPM4,ZNF384,IGFN1,PRMT8,ADGRG1,CHGA,UBTF,CNTN1,BEST1,PRRX1,IFFO1,ACBD5,SF1,CRMP1,PTPA,RGS6,FMN2,ARHGEF4,NOS1AP,ANKS1B,PSMD13,LRP8,CEP170,BLOC1S6,ZC3H11A,KCNA6,PTPRE,C1orf109,SV2A,KCNJ11,PEX5,DLG3,CAB39L,DNAH9,RAB5B,DPP6,ABI1,DTNA,RTN4,BSDC1,ABCC9,RET,RFX5,JMJD1C,ARHGEF10L,RBM12,GPR61,CBLN2,RAVER2,SLC4A10,LRRC23" MicroRNA hsa-miR-382:mirSVR_lowEffct hsa-miR-382:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-41 1.26E-37 7.73E-40 7.09E-39 108 1738 "ATAT1,MDM4,CSMD3,NDRG2,RTN1,AMER2,SLC44A5,TOMM40L,GPR158,BBOX1,MOBP,SOX6,CDC42BPA,PPFIA1,ITSN1,APC,NLGN1,AQP4,ZNF365,RUFY2,ARHGAP5,SLC8A2,YPEL4,CCDC88A,DACH2,CADPS,ASCL1,GPR153,SLCO1A2,TAGLN3,SLN,ATM,MEGF11,USP33,SON,WDTC1,TNIK,ARPP21,ADAM15,NCAM1,CLASP2,SMOC1,ERBIN,DCAF5,HEPN1,SEPT3,VAMP1,OS9,POPDC3,CAMSAP2,UNC5D,ADGRL3,GOLGB1,KLHL4,GPM6A,TCF7L2,ZEB1,PTBP2,MFSD2A,TJP1,KCNK10,MAEL,PAX6,PCDH8,CDH8,ARHGAP19,LGI1,PCSK2,PDE1C,ANO5,CHGA,CASC2,TMEFF2,GDAP1L1,NRXN1,FAM181B,CNTN1,BTF3L4,FAT3,CRMP1,ATRNL1,DZIP3,FMN2,PRKCZ,PROX1,KIAA0513,TOMM20,SIRPA,DNAJC6,PTHLH,PRDM2,CEP170,PTPRZ1,NTM,PCDH15,KCNN3,SNX27,DLG2,TMEM255A,ABI1,RASGRF1,DBX2,DTNA,VANGL2,SYT15,RBM12,RPRD1A,C2orf80" MicroRNA hsa-miR-633:mirSVR_lowEffct hsa-miR-633:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-41 1.28E-37 7.78E-40 7.14E-39 111 1838 "ADGRV1,LDLRAD3,SLC25A25,CSMD3,ADARB2,SLITRK1,CDC7,SLC44A5,SCN3A,FGF1,FGF14,SOX6,SGIP1,PPFIA1,ITSN1,PKP4,DOCK10,MAGI3,SLITRK3,BCAN,CACHD1,JAKMIP3,AQP4,MIER1,SLCO1A2,CAPRIN2,BRINP2,MTR,ASTN1,TMEM108,SNAP25,ATM,CCDC181,PHYHIPL,DKK3,ARPP21,KIF1B,GART,NAP1L2,NFASC,C11orf87,ERBIN,GLS,BTRC,ADGRL3,CACNA1A,GPM6A,PRLHR,ZEB1,TCF12,PTBP2,NUMA1,GRID1,TF,TGFBR3,MFSD2A,GUCY1A1,TJP1,KCNK10,REPS2,IGSF21,PCDH9,DCLK1,MAGI1,PDE1A,ANO5,ZBED5,CADM1,NOMO2,NMT2,DNAJC12,CNTN1,PRRX1,MFSD4A,ETNPPL,PPP3CB,KCNT2,OSBPL3,ATRNL1,VCAN,DZIP3,IGSF1,PUM1,NOS1AP,MASP1,SYTL2,ANKS1B,PLPPR5,SYNC,ITGAV,PTHLH,MAGI2,OCIAD1,PTPRD,PTPRO,KCNK1,KCNK2,KCNMA1,DNM2,ABI1,FAM13C,RTN4,PAK5,NUP214,ZNF248,RBM12,SH3GLB1,RPRD1A,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-628-3p:mirSVR_lowEffct hsa-miR-628-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-41 1.43E-37 8.64E-40 7.92E-39 101 1515 "ABAT,LGR4,MRVI1,FABP7,HOGA1,LRRC7,BCAR3,FOXG1,SOX6,ANK3,PKP4,SESN3,GAS7,TACC2,SYBU,AQP4,SLC1A7,MSR1,LRRC55,SLCO1A2,ASPH,SORCS3,RCOR3,CCDC181,ATP2B2,SCN3B,MYT1L,TNIK,ILDR2,GAD2,NMNAT2,B4GALNT1,ARPP21,SALL3,GART,BCL2L2,ADHFE1,NEUROD1,AJAP1,ARHGEF7,GLS,VAMP1,ADGRL3,VWC2,LILRA1,TCF7L2,TCF12,EML4,SYT6,GRIA1,GRIA4,GRIK2,GPR88,LINC00839,CRB1,TGFBR3,TJP1,PAH,MAEL,RBFOX2,PCSK2,CIART,BEST3,HMGB1,TMEFF2,NRXN1,ANLN,CNTN1,NXPH1,CRMP1,SNCAIP,KCNT2,VCAN,PRKAB2,FMN2,EDRF1,MASP1,PLPPR5,ZNF385B,SYNC,PRDM2,CEP170,BLOC1S6,KCNA2,OLFM3,KCNA4,PTPRZ1,KCNK1,PCDH15,DLG2,TMEM255A,SLC17A6,CAMK1G,JMJD1C,FAM135B,ATL1,TTLL7,VWA5A,SLC4A10,ELAVL4,RPE65" MicroRNA hsa-miR-892a:mirSVR_lowEffct hsa-miR-892a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.01E-41 1.63E-37 9.82E-40 9.00E-39 109 1776 "SDE2,ACER3,TMEM74,MRVI1,ADD3,SNX30,FCGR1A,TOMM40L,PLA2G6,FHL1,ELMOD1,AMPH,ERICH3,CACHD1,NLGN1,API5,LRRC55,SLCO1A2,SLIT1,SORCS3,SMARCE1,SNAP25,ATM,CCDC181,ZSWIM8,ARPP21,NAP1L2,NCAM1,BCL2L2,STOX1,NELL1,SEPT3,FAM168A,CASTOR3,SYT4,LUZP2,DCLK2,SEMA4A,CAMTA1,TMEM136,PRUNE2,GPM6B,CACNB2,AZIN2,EML4,GRID1,GRIK3,OLR1,CCKBR,CRB1,TGFBR3,TMEM9,ZDHHC22,MAEL,REPS2,PADI2,PCDH9,RBFOX2,LGI1,PDE3B,PDYN,ZMYND8,TMEFF2,GDAP1L1,CADM1,KIAA1549L,TJP2,FTO,FAT3,PNKD,CRLS1,TENM4,MICAL2,OSBPL3,NCAN,RBPJ,PRKAB2,PRKCG,PRKCZ,USP54,NRSN1,KIAA0408,TOX,WBP1L,GON4L,SPIRE1,DNAJC6,PTHLH,CADM2,KCNA2,OCIAD1,PTPRD,PLPPR4,PTPRO,NTM,RABGAP1L,NKAIN1,PID1,SLC17A6,PAK5,SLC6A15,ZYG11B,ATL1,RBM12,VWA5A,ARHGAP12,C2orf80,EPB41L2,RCAN2" MicroRNA hsa-miR-2861:mirSVR_lowEffct hsa-miR-2861:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-41 1.66E-37 9.93E-40 9.11E-39 104 1613 "EPS8,LOC100128239,MAP6,MAPT,SRARP,EMID1,SYNDIG1,MEG3,FAM43B,MRVI1,CSMD2,MDM4,GRAMD1B,TUBB4A,DRAXIN,TOMM40L,SCNN1D,KIAA1109,ASIC4,HPCAL4,MOBP,TRIM46,ASRGL1,USP28,CNIH2,PPM1E,BCAN,ST3GAL3,SLC6A9,YPEL4,ASCL1,SLCO1A2,SORCS3,ALDH4A1,TMEM151A,ATP1A3,MYBPC1,WDTC1,SOX10,TTLL9,ADAM15,FXYD6,RND1,PCDH11X,MYRF,MMD2,CNTN2,KLHL4,CACNB2,AZIN2,NUMA1,BRSK2,ATP13A2,OPCML,CRB1,TMEM257,DAAM2,TNFRSF1B,PC,PADI2,DCLK1,LGI1,PDE2A,FNDC5,CHGA,ASIC3,CHRM1,HPCA,DUSP26,NLGN3,CAMKV,PIK3CD,CPT1C,CCSER2,ST8SIA5,PLXNB3,C11orf49,SF1,MICAL2,ATRNL1,PLCH2,DZIP3,PLPP4,FAM131B,NOS1AP,MASP1,TOMM20,PSMD13,PTPRE,TMCC2,KCNJ11,NKAIN1,RAB3IL1,RAB5B,SLC25A48,SLC25A41,RASGRF1,BSDC1,RNF220,SSPN,SIDT2,VWA5A,BSCL2,PRRT4" MicroRNA hsa-miR-205:mirSVR_lowEffct hsa-miR-205:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.32E-41 1.80E-37 1.07E-39 9.81E-39 115 1981 "MAP6,TMEM74,SYT9,MRVI1,ARID1A,KCNIP2,ERMN,ADORA1,GPR158,HOGA1,FGF1,FHL1,MOBP,SOX6,CDC42BPA,RASA3,PI16,PPM1E,APBA2,NTNG1,GPAM,DGKD,SHTN1,USP16,ZNF365,LRRC55,PKNOX2,DACH2,SCMH1,PDE8B,CAPRIN2,DDX25,SORCS3,SON,B3GALT2,CAB39,NEK6,KIF1B,ADGRB2,C11orf87,DCAF5,RND1,GLS,VAMP1,LUZP2,DDHD2,CAMTA1,NODAL,TMEM136,ANO4,TBX15,PRUNE2,TCF7L2,NRGN,GRIK3,GRM3,OMG,SPX,LEFTY2,P2RX7,TLL2,ZDHHC22,CDC42,PCDH9,CDH10,DCLK1,RBFOX2,PRMT8,PIRT,FNDC5,HMGB1,CAMKV,NEGR1,OPALIN,PMP2,BTF3L4,SPATA6,NSD2,NXPH1,CHD1L,MED1,PTPA,PPP2R5C,SNCAIP,FEZ1,PRKCZ,NRSN1,PUM1,BRINP3,PHYHIP,PLPPR5,PTCH1,JAKMIP2,BDNF-AS,PTHLH,CEP170,MAGI2,BLOC1S6,ZC3H11A,SMG7,KCND3,KCNJ10,KCNK2,DLG2,KIF2A,HS3ST4,DNAH9,RTN4,ZYG11B,NUP214,RFX5,INSYN2,ZNF248,ARHGAP12,EPB41L1" MicroRNA hsa-miR-3154:mirSVR_highEffct hsa-miR-3154:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.98E-41 2.16E-37 1.28E-39 1.17E-38 82 968 "PRR5L,RTN3,LDLRAD3,KLHL32,SORCS1,AMER2,FGR,FHL1,MOBP,MOG,ITSN1,AQP4,MIER1,CCDC88A,SLCO1A2,SLIT1,RCOR3,PHYHIPL,GABBR1,SON,AHCYL1,JPH4,NCAM1,CLASP2,NDUFA5,DCAF5,RCOR2,NEUROD1,ARHGEF7,GLS,VAMP1,PCDH11X,ZNF638,SEMA4A,TBX15,ZEB1,EML4,GRIA4,GRIK2,USP2,TMEM9,TMEM257,CDC42,TNR,PCDH9,HERC2P3,ZFYVE9,NRXN1,ST8SIA5,FAM181B,C11orf49,MEAF6,COL9A2,POU3F4,PNKD,SF1,PTPA,FEZ2,DOCK7,NRSN1,KLK6,PRDM2,HP1BP3,CEP170,ZC3H11A,OCIAD1,SMG7,RABGAP1L,TMCC2,PCDH15,PID1,RGR,RGS7,ZNF248,SEC61A2,CACNG7,PIANP,RPRD1A,ELAVL4,EPB41L1,EPB41L2,UEVLD" MicroRNA hsa-miR-4254:mirSVR_lowEffct hsa-miR-4254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.05E-41 3.28E-37 1.93E-39 1.77E-38 114 1959 "PRR5L,ACER3,APC2,TMEM74,EXTL1,MEG3,KLHL32,ADCY2,ADORA1,GPR158,LRRC7,BBOX1,HPCAL4,FOXG1,TRIM46,SFPQ,ANK1,ANK2,PPFIA1,MAGI3,DGKZ,MADD,SLC8A2,SLC8A3,NAXD,SORCS3,C10orf105,ALDH4A1,DKK3,SOX5,KIF21B,SOX10,AHCYL1,TTLL9,ADGRB2,COLGALT2,BCL2L2,ALDH1L1,STOX1,RCOR2,NELL1,GANAB,ACSBG1,CASTOR3,ZNF638,NHLH1,ADGRL3,ANO4,CACNB2,VXN,GRIA4,LINC00839,USP2,DAAM2,PDE2A,PIRT,BEST3,CHI3L2,TUB,SEMA5B,OPALIN,FADS2,FTO,CABP1,CELF5,PRRX1,MFSD4A,CHD1L,SF1,RNF14,PPP2R5C,PPP3CB,OSBPL3,RBPJ,CMTM5,PLPP4,PRKCZ,PUM1,NOS1AP,MASP1,WBP1L,PHYHIP,PSMD13,PLPPR1,PMEPA1,DKFZp779M0652,CSDE1,MED24,BLOC1S6,KCNA1,C1orf109,TMCC2,CAB39L,NKAIN1,HS3ST4,WIPF2,RAB3IL1,DNAH9,PLEKHB2,FAM66C,FAM57B,RASGRF1,GNE,DTNA,ABCC9,RET,RFX5,ABI2,VWA5A,ARHGAP12,CBLN2,SLC4A10,RPE65,EPB41L1" MicroRNA hsa-miR-329:mirSVR_lowEffct hsa-miR-329:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.29E-41 3.40E-37 1.99E-39 1.83E-38 107 1724 "SYT9,FAM43B,LDLRAD3,ARID1A,RTKN,CSMD3,SEMA6A,PKP4,APBA2,NTNG1,ZNF365,ARFGAP2,SLC8A3,NSG2,DACH2,CGREF1,SLCO1A2,SMARCE1,RCOR3,ATM,ATP2B2,WDTC1,SOX5,ZCCHC24,KIF21B,CADM3,GAD2,ZSWIM8,LHFPL4,ADAM15,KIF1B,CPLX2,NPAS3,NCAM1,AJAP1,VAMP1,PCDH11X,NHLH1,CAMTA1,ADGRL3,ANO4,TBX15,PRUNE2,CACNB2,AZIN2,NUMA1,GRIA2,GRIA4,GRIK2,CYB561A3,OPCML,CRB1,P2RX7,TIE1,TMEM9,CDC42,CDH10,ARHGAP19,TPM3,PCSK2,IGFN1,PRMT8,CADM1,KIAA1549L,CAMKV,OPALIN,FAT3,POU3F2,CRLS1,FEZ1,RBPJ,DOCK7,DZIP3,FMN2,CTNND1,NOS1AP,PROX1,TOMM20,PLPPR5,PTCH1,PRDM2,HP1BP3,COPS7A,MED24,PTPRD,PLPPR4,PTPRO,SV2A,SRGAP3,AK5,PCDH15,DLG2,CAB39L,KIF2A,WIPF2,ATG16L1,DTNA,ABCC9,CAMK1G,RGS7,VANGL2,RNF220,SLC39A12,RBM12,RPRD1A,EN2,EPB41L2" MicroRNA hsa-miR-1:mirSVR_lowEffct hsa-miR-1:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.21E-41 3.90E-37 2.27E-39 2.08E-38 109 1793 "MAP6,SYT9,CSMD3,KLHL32,WAC,SORCS1,ADORA3,FCGR1A,GPR158,HOGA1,TESK2,SCN3A,LINC00461,FGF14,SEMA6A,UNC79,MOBP,MOG,AMPH,SFPQ,CDC42BPA,DOCK10,SESN3,NTNG1,CACHD1,SYBU,SHTN1,SLC8A2,SLC8A3,SHANK2,SLCO1A2,DLL3,TMEM151A,TNIK,SOX10,NMNAT2,ENKUR,TTLL9,CPLX2,NFASC,NCAM1,C11orf87,BCL2L2,NDUFA5,SEPT3,FAM168A,ARHGEF7,VAMP1,GNAS,GNG4,MYRF,UNC5D,MMD2,BTRC,CACNA1A,CACNB2,LILRA1,TCF7L2,PTBP2,SYT6,GRIA2,GRIK2,CRB1,TGFBR3,ZDHHC22,PAX6,TNR,TPM4,ACOT7,CASC2,HEPACAM,CADM1,NRXN1,OPALIN,TJP2,FADS2,BEST1,CNRIP1,ATRNL1,NCAN,SDC3,RAB39A,BRINP3,TOX,WBP1L,ANKS1B,GON4L,PLPPR5,PRDM2,LRP8,MAGI2,SRGAP3,PCDH15,KCNMA1,HS3ST4,WIPF2,DNM2,RALGDS,C12orf4,GNE,ZYG11B,FAM135B,ZNF248,SH3GLB1,RERGL,ABI2,TMEM100,EPB41L1,RCAN2" MicroRNA hsa-miR-936:mirSVR_highEffct hsa-miR-936:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.91E-41 4.29E-37 2.48E-39 2.27E-38 88 1143 "MAP6,TMEM74,MEG3,ADGRV1,CLIP1,NLGN4X,HOGA1,SCN3A,LINC00461,BCAR3,ELMOD1,SELL,CNIH2,PKP4,APC,MAGI3,CCDC80,SLITRK3,CACHD1,NLGN1,LRRC4C,API5,MIER1,SLC2A5,MSR1,SLC8A3,CCDC88A,ASCL1,SORCS3,ATM,PHYHIPL,MEGF11,GABBR1,ENKUR,JPH4,GART,NCAM1,LMO3,CLASP2,NDUFA5,ERBIN,NELL1,RGL1,ZNF638,SYT4,CAMSAP2,UNC5D,GOLGB1,LILRA1,CRB1,LEFTY2,TGFBR3,LGI1,TPD52,LINC01102,ZMYND8,CASC2,CADM1,MEAF6,MFSD4A,POU3F2,ATRNL1,FMN2,IGSF1,PROX1,MASP1,TOX,ANKS1B,CA10,CNIH3,BLOC1S6,PTPRE,AK5,KCNK2,TMEM255A,ABI1,DSCAM,RASGRF1,GNE,RTN4,PAK5,L1CAM,ZNF248,SEC61A2,SH3GLB1,SLC4A10,EPB41L1,BAALC" MicroRNA hsa-miR-519b-3p:mirSVR_highEffct hsa-miR-519b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.12E-41 4.40E-37 2.53E-39 2.32E-38 97 1410 "CNTNAP3,MDM4,F3,RTN1,GALNT13,GPR158,HOGA1,TESK2,SCN3A,LINC00461,LRRC7,FGF14,FOXG1,MOG,ERICH3,USP28,ITSN1,SLITRK3,SYBU,API5,SHTN1,PAAF1,BCO1,RUFY2,MSR1,LRRC55,CCDC88A,NAXD,CAPRIN2,RCOR3,ATM,GABBR1,USP33,MYT1L,B3GALT2,SOX5,GAD2,B4GALNT1,ARPP21,SPART,C11orf87,CLASP2,SMOC1,ERBIN,NELL1,ADHFE1,NEUROD1,GANAB,GLS,ZNF638,LUZP2,CAMTA1,CAMSAP2,MYRF,ADAMTS8,GPR88,LINC00839,TGFBR3,HPS5,PDE3B,BEST3,TLX1,ZFYVE9,CCSER2,BTF3L4,PMS2,NSD2,CRLS1,PPP3CB,CHD5,DOCK7,NRSN1,MASP1,PSD,ANKS1B,CA10,PTHLH,CSDE1,MAGI2,PLPPR4,KCNJ10,KCNK1,CAB39L,RAB5B,PID1,SLC25A48,SLC17A6,ATG16L1,ABCC9,ZYG11B,RET,RFX5,SSPN,FGFBP3,ARHGAP12,RAVER2,UEVLD" MicroRNA hsa-miR-1231:mirSVR_lowEffct hsa-miR-1231:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.12E-41 4.94E-37 2.82E-39 2.59E-38 104 1633 "SERPINA3,SYT9,SYNDIG1,MRVI1,ECSIT,LDLRAD3,CSMD2,MDM4,CLIP1,DSCAML1,RXRG,CHST15,TOMM40L,LRRTM4,LRRC7,GOLGA7B,HPCAL4,FOXM1,TRIM46,ANK1,PPFIA1,SORBS1,JAKMIP3,RPH3A,CCDC88A,ARFGAP1,CAPRIN2,RCOR3,ADGRA1,NRG3,WDTC1,SOX5,ENKUR,SALL3,NEK6,ADGRB2,C11orf87,ZNF302,SMOC1,ERBIN,FAM168A,ARHGEF7,ZNF638,LUZP2,GNAS,CDK5R2,WWC1,TMEM136,ANO4,TBX15,CACNA1A,GPR17,GPR19,EML4,CAMK2A,VXN,GRIA4,GRIN1,OLR1,P2RX7,CDH10,MAGI1,TLX1,DUSP26,GDAP1L1,NRXN2,SULT4A1,PMP2,BEST1,COL9A2,MFSD4A,SF1,SNCAIP,RGS6,ATRNL1,VCAN,PRKACB,KIAA1755,MAPK10,EDRF1,MASP1,TOX,KIAA0513,SPIRE1,ELMO1,CNIH3,HP1BP3,MAGI2,KCNA1,PTPRD,PLPPR4,SRGAP3,NTM,KCNJ9,KCNN3,DNM2,FAM66C,PAK5,L1CAM,JMJD1C,ARHGEF10L,PHC2,SEC61A2,RNF220" MicroRNA hsa-miR-589*:mirSVR_highEffct hsa-miR-589*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.61E-41 5.20E-37 2.96E-39 2.71E-38 111 1866 "DPF1,RABEPK,ACLY,MEG3,EYA1,F3,CLIP1,GALNT13,SORCS1,AMER2,FCGR1A,TESK2,LINC00461,LRRC7,PPFIA1,PKP4,APC,DGKD,NLGN1,API5,USP16,SLC2A5,MADD,MTR,SMARCE1,RCOR3,TMEM108,NRG3,USP33,GAD2,ARPP21,EMC1,NAP1L2,NPAS3,NASP,DCAF5,GANAB,RND1,ZNF638,SYT4,LUZP2,DDHD2,CAMSAP2,ADGRL3,NPPA,CACNB2,B4GALNT4,PTBP2,EML4,CAMK2G,CECR2,SYT6,GRIA2,CRB1,TGFBR3,AIFM1,CD81,MAEL,CDC42,TNS1,PCDH9,CDH10,TPD52,TPM3,MAGI1,PDYN,HMGB1,CHGA,HNRNPK,JAM2,NLGN3,CADM1,CCSER2,OPALIN,BEST1,MED1,SNCAIP,PPP3CB,KCNT2,FEZ2,MICAL2,DOCK7,PRKCZ,EDRF1,FGFR1OP2,KIAA0513,WBP1L,GON4L,TOMM20,PTCH1,BDNF-AS,PRTFDC1,HP1BP3,CSDE1,ZC3H11A,PTPRO,NTM,KCNJ9,KCNMA1,RAP1GAP,SUSD4,GNE,FAM13C,PAK5,ABCC9,RFX4,ATL1,SEC61A2,FGFBP3,TMEM100,EPB41L1" MicroRNA hsa-miR-206:mirSVR_lowEffct hsa-miR-206:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.00E-40 5.41E-37 3.06E-39 2.81E-38 110 1833 "MAP6,SYT9,CSMD3,KLHL32,WAC,SORCS1,ADORA3,FCGR1A,GPR158,SNX32,TESK2,SCN3A,LINC00461,FGF14,UNC79,MOBP,MOG,AMPH,SFPQ,CDC42BPA,DOCK10,NTNG1,CACHD1,SYBU,SHTN1,SLC8A2,SLC8A3,SHANK2,SLCO1A2,DLL3,TMEM151A,TNIK,SOX10,NMNAT2,ENKUR,TTLL9,KIF1B,CPLX2,NFASC,NCAM1,BCL2L2,NDUFA5,SEPT3,FAM168A,ARHGEF7,VAMP1,GNAS,GNG4,UNC5D,MMD2,BTRC,CACNA1A,CACNB2,LILRA1,TCF7L2,PTBP2,SYT6,GRIA2,GRIK2,CRB1,TGFBR3,ZDHHC22,PAX6,TNR,PADI2,TPM4,ACOT7,CASC2,HEPACAM,CADM1,NRXN1,CAMKV,OPALIN,TJP2,BEST1,ATRNL1,NCAN,SDC3,FMN2,RAB39A,ARHGEF4,CTNND1,BRINP3,TOX,WBP1L,ANKS1B,GON4L,PLPPR5,PRDM2,LRP8,CEP170,MAGI2,SV2A,SRGAP3,PCDH15,KCNMA1,HS3ST4,WIPF2,DNM2,SUSD4,GNE,ZYG11B,FAM135B,ZNF248,SH3GLB1,RERGL,ABI2,TMEM100,EPB41L1,RCAN2" MicroRNA hsa-miR-515-3p:mirSVR_lowEffct hsa-miR-515-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-40 6.04E-37 3.39E-39 3.11E-38 94 1324 "EMID1,CSMD3,ADCY2,GALNT13,DRAXIN,HOGA1,KIAA1109,FGF1,SLC30A10,FOLH1,PKP4,APBB1,APC,MAGI3,SHTN1,PAAF1,MSR1,ARFGAP2,YPEL4,SLC8A3,PDE8B,CAPRIN2,MTR,ADGRA1,PHYHIPL,SCN3B,USP33,B3GALT2,TNIK,CAB39,NMNAT2,JPH4,TTLL9,FXYD6,SPART,C11orf87,STOX1,DCAF5,RGL1,KIRREL3,MLC1,CDK5R2,TMEM136,TCF7L2,HAP1,CAMK2G,VXN,GRIA1,CCKBR,LINC00839,CRB1,P2RX7,ZFP91,IGSF21,C1orf94,PTGDR2,LGI1,MAGI1,PDYN,ASIC3,CASC2,HEPACAM,DUSP26,CADM1,TJP2,SLC36A4,FAT3,PPP3CB,RGS6,FEZ2,FEZ1,DOCK7,IGSF1,EDRF1,DPYSL5,GON4L,PTHLH,PRDM2,CEP170,KCNA1,OCIAD1,PTPRE,NTM,KCNJ11,KCNK1,KCNK2,TMEM255A,GOPC,RTN4,BSDC1,PHC2,SYT15,PIANP,FGFBP3" MicroRNA hsa-miR-432*:mirSVR_lowEffct hsa-miR-432*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-40 6.61E-37 3.69E-39 3.39E-38 99 1479 "ZFYVE27,RTN3,ATAT1,CSMD2,CSMD3,ADCY2,KLRC4,WAC,CDC7,AMER2,FOXRED2,FCGR1B,CHST15,HOGA1,LRRC7,MOBP,PI16,CNIH2,PPM1E,APC,GPAM,JAKMIP3,MIER1,LRRC55,ASPH,RCOR3,GABBR1,SCN3B,SON,WDTC1,ZSWIM8,ENKUR,ARPP21,EMC1,CPLX2,NFASC,ALDH1L1,NEUROD1,VAMP1,PCDH11X,ZNF638,GNG4,WSCD1,CACNB2,ZEB1,HAP1,PTBP2,NUDT21,PCDHGA3,GRIA4,CRB1,LEFTY2,TIE1,TMEM9,DAAM2,CDC42,PADI2,LGI1,TPM4,ZMYND8,CASC2,TUB,CCSER2,VAV2,CNTN1,MEAF6,CELF5,BTF3L4,PACSIN1,FAAP20,MFSD4A,CHD1L,PTPA,RGS6,NKAIN4,CSF3R,PRKAB2,KIAA1755,CTNND2,MAPK8,MAPK10,NOS1AP,BDNF-AS,STMN4,OCIAD1,PTPRE,KCNN3,PEX5,NKAIN1,PID1,SLC6A15,RET,RFX4,ZNF248,RNF220,RPRD1A,FGFBP3,PRRT4,EPB41" MicroRNA hsa-miR-154:mirSVR_lowEffct hsa-miR-154:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-40 8.83E-37 4.91E-39 4.50E-38 96 1391 "SERPINA3,ACER3,MBP,LDLRAD3,SLC25A25,ADAR,ADARB2,CLIP1,RTN1,ADD3,SORCS1,ERMN,TESK2,KIAA1109,FOXG1,SOX6,CDC42BPA,PPFIA1,PPM1E,DOCK10,SORBS1,BCAS1,ZNF365,RPH3A,BCO1,LRRC55,ASCL1,GPR153,CAPRIN2,ATP1A2,SON,SOX10,NPAS3,NFASC,NCAM1,RND1,SEPT3,GLS,CASTOR3,LUZP2,DDHD2,ADGRL3,GPM6B,GRM3,MFSD2A,TMEM257,PAH,PCDH8,TPM4,PDE4B,FNDC5,HAPLN2,TMEFF2,KIAA1549L,NEGR1,CCSER2,PLXNB3,CNTN1,PMP2,MEAF6,SLC25A27,NSD2,RNF14,SNCAIP,RGS6,VCAN,PRKACB,FGFR1OP2,KIAA0513,PLPPR5,ZNF385B,DNAJC6,CA10,BDNF-AS,MAGI2,BLOC1S6,OLFM3,OCIAD1,PTPRE,ARNT2,DLG2,CAB39L,PLEKHB2,GNE,BSDC1,RGS10,PHC2,ZNF248,RBM12,SH3GLB1,RERGL,FGFBP3,ARHGAP12,PRRT4,EPB41L2,RASGRP2" MicroRNA hsa-miR-15b:mirSVR_highEffct hsa-miR-15b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.75E-40 9.47E-37 5.23E-39 4.80E-38 98 1454 "CDHR1,RTN3,SYNDIG1,EYA1,CSMD2,GALNT13,CDC7,TMEM156,SCN3A,DISP3,LRRC7,ELMOD1,SLC30A10,SELL,ANK2,SH3GL2,PPM1E,GPAM,NLGN1,ST3GAL3,BCAS1,MSR1,CSPG5,SLN,RCOR3,SNAP25,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,NAP1L2,NPAS3,NFASC,BCL2L2,ADHFE1,PHLDB1,ACSBG1,SYT4,KAZN,GNAS,BTRC,WWC1,CACNA1E,VSTM2A,OMG,TGFBR3,CDC42,PCDH9,PDE1A,PDE3B,BEST3,HMGB1,CADM1,NRXN1,OPALIN,BTF3L4,PRRX1,NXPH1,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,MICAL2,RBPJ,PRKCG,PKN2,MASP1,SYTL2,ANKS1B,PTCH1,JAKMIP2,PMEPA1,PTHLH,CSDE1,PTPRD,KCNJ11,KCNK1,KCNK2,PEX5,DLG2,KIF2A,DNAH9,PID1,TMEM255A,RET,RFX4,RFX5,SEC61A2,SIDT2,RBM12,ABI2,ARHGAP12,EN2,TMEM100,RCAN2" MicroRNA hsa-miR-4286:mirSVR_lowEffct hsa-miR-4286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-40 9.76E-37 5.37E-39 4.92E-38 90 1213 "TTYH1,SERPINA3,LOC100128239,CNTNAP3,MEG3,LDLRAD3,MDM4,CSMD3,SORCS1,FCGR1A,TESK2,KIAA1109,FGF1,ASIC4,MOBP,FOXG1,MOG,C1orf61,SOX6,SGIP1,PI16,PPM1E,APBB1,DGKD,SYBU,NLGN1,PAAF1,DACH2,SCMH1,ARFGAP1,ASPH,MTR,USP33,NFASC,NCAM1,COLGALT2,GFRA1,RCOR2,PHLDB1,SEPT3,GLS,NHLH1,C1QC,ROBO3,CDK5R2,KLHL4,CACNB2,PCDHGA3,GRIA4,OLR1,PTPN5,FBXL16,REPS2,CDC42,PADI2,FNDC5,PFKFB3,CHRM1,GDAP1L1,ZFYVE9,TJP2,CP,MED1,PTPA,RBPJ,PRKAB2,MASP1,ZBTB16,SPIRE1,SIRPA,LRP8,COPS7A,RGMA,PARD6A,KCNH1,SV2A,SRGAP3,KCNJ10,PCDH15,PID1,TMEM255A,SLC17A6,DPP6,ABI1,ABCC9,NUP214,RNF220,EFNA3,OLIG2,RCAN2" MicroRNA hsa-miR-570:PITA hsa-miR-570:PITA_TOP PITA 1.92E-40 1.04E-36 5.69E-39 5.22E-38 83 1016 "ABAT,LGR4,RTN3,ARID1A,SLITRK1,SORCS1,NLGN4X,SEMA6A,ELMOD1,AMPH,PPM1E,NTNG1,GAS7,SLITRK3,AQP4,SLC1A2,PKNOX2,BRINP2,PHYHIPL,ATP2B2,PALLD,MYBPC1,SOX1,MYT1L,ZCCHC24,SALL3,NCAM1,CLASP2,COLGALT2,DCAF5,VAMP1,PCDH11X,CAMTA1,CAMSAP2,GPM6A,VWC2,LRIT2,GPR19,TCF12,CAMK2A,CAMK2G,GPR88,ZFP91,REPS2,DCLK1,HRH3,SEZ6L,TLX1,CADM1,NRXN1,UBTF,MEAF6,PRRX1,FAT3,MED1,PPP3CB,FMN2,PLPP4,NRSN1,FAM131B,PROX1,TOX,WBP1L,RIMS3,SIRPA,PTCH1,CA10,PMEPA1,CADM2,PTPRD,SMG7,KCNK2,DLG3,NKAIN1,CALN1,SLC17A6,FAM13C,RTN4,RBM12,SH3GLB1,ABI2,TMEM100,EPB41L2" MicroRNA hsa-miR-647:mirSVR_lowEffct hsa-miR-647:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.98E-40 1.07E-36 5.81E-39 5.33E-38 106 1713 "LOC100128239,ZFYVE27,CDHR1,SLC25A25,SORCS1,GRAMD1B,TOMM40L,TRIM46,SEMA6C,PPFIA1,ITSN1,PKP4,BCAN,ST3GAL3,SLC1A7,LRRC55,SLC14A1,SCMH1,ASCL1,ARFGAP1,ASPH,SMARCE1,KBTBD12,ALDH4A1,DKK3,SON,WDTC1,CADM3,ZSWIM8,INKA2,NELL1,KIRREL3,PHLDB1,SEPT3,SLCO1C1,NFIA,GLS,RHBDL3,SYT4,KAZN,SEMA4A,CAMTA1,MMD2,TBX15,DIRAS1,HAP1,PTBP2,NUMA1,OPCML,LINC00839,CRB1,TMEM25,TMEM9,ZDHHC22,TNFRSF1B,CDC42,PADI2,MAGI1,PDE2A,LINC01102,NTSR2,BEST3,CHGA,ARHGAP22,GDAP1L1,CADM1,CAMKV,FTO,CELF5,BEST1,BTF3L4,SF1,SNCAIP,PPP3CB,RGS6,VCAN,USP54,IGSF1,MASP1,WBP1L,ANKS1B,PHYHIP,PLPPR5,ITGAV,COPS7A,CDH20,PTPRO,KCNK2,DLG2,NKAIN1,KIF2A,HS3ST4,RALGDS,L1CAM,USH1C,RFX4,INSYN2,ARHGEF10L,PHC2,RNF220,RPRD1A,ABI2,ELAVL4,PRRT4,EPB41L2,LRRC23" MicroRNA hsa-miR-145*:mirSVR_lowEffct hsa-miR-145*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.98E-40 1.07E-36 5.81E-39 5.33E-38 103 1615 "TTYH1,MAP6,SYT9,KLHL32,SORCS1,ADORA1,GPR158,LINC00461,FHL1,MOG,ERICH3,SGIP1,CDC42BPA,ANK2,USP28,SLITRK3,NLGN1,BCAS1,API5,SLC14A1,SLCO1A2,SMARCE1,B3GAT1,SNAP25,PALLD,MYT1L,TNIK,SOX10,NMNAT2,FXYD6,NFASC,COLGALT2,ALDH1L1,STOX1,ZNF302,ERBIN,AJAP1,RHBDL3,CASTOR3,ZNF638,ADGRL3,ANO4,TBX15,NEU4,LILRA1,PTBP2,NUDT21,EML4,CECR2,VSTM2A,GPR88,LEFTY2,TMEM9,TMEM257,KCNK10,MAEL,CDC42,SEZ6L,LGI1,PDE4B,PDYN,ANO5,CASC2,MS4A7,CHRNB2,TJP2,FADS2,MEAF6,NXPH1,MED1,SNCAIP,NKAIN4,KCNT2,VCAN,FMN2,KIAA1755,RAB39A,FGFR1OP2,WBP1L,ITGAV,CADM2,MAGI2,ZC3H11A,OCIAD1,C1orf109,PTPRZ1,KCNJ9,RABGAP1L,KCNJ10,DLG2,CAB39L,DNAH9,SLC25A48,ATN1,DTNA,ZYG11B,NUP214,USH1C,SYT15,RPRD1A,YY1AP1,PRRT4,SEZ6" MicroRNA hsa-miR-378*:mirSVR_lowEffct hsa-miR-378*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-40 1.14E-36 6.12E-39 5.61E-38 112 1916 "PRR5L,ACLY,MBP,ACTN2,ADGRV1,F3,ASIC4,HPCAL4,FOXG1,MOG,FOXM1,SFPQ,PI16,PPM1E,BCAN,SORBS1,RUFY2,LRRC55,NSG2,SLIT1,NAXD,ASPH,B3GAT1,ATP2B2,SOX5,AHCYL1,NMNAT2,ARPP21,ADAM15,KIF1B,ZNF638,GNAS,NODAL,CAMSAP2,UNC5D,MMD2,PRUNE2,CACNA1E,PRLHR,ZEB1,CAMK2G,CECR2,BRSK2,AKNA,GRIA1,GRIA2,ATP13A2,OLR1,OPCML,CRB1,GUCY1A2,P2RX7,TMEM9,TLL2,PAH,MAEL,CDH8,LGI1,ZNF384,PDYN,TMPRSS5,CHRM1,CASC2,SERPINE2,A2ML1,SULT4A1,PMP2,BEST1,NSD2,CRLS1,SNCAIP,KCNT2,FEZ1,ATRNL1,SDC3,RAB39A,PRKCG,PLPP4,MAPK10,NOS1AP,FGFR1OP2,ZBTB16,SYTL2,GON4L,PRDM2,LRP8,ZC3H11A,OLFM3,OCIAD1,KCNC1,PARD6A,SV2A,RABGAP1L,TMCC2,ARNT2,KCNK2,PCDH15,KCNMA1,SLC25A48,DPP6,SLC25A18,RASGRF1,FAM13C,L1CAM,NUP214,RFX5,ARHGEF10L,SSPN,RBM12,GPR61,SLC4A10,EPB41L1" MicroRNA hsa-miR-302e:mirSVR_lowEffct hsa-miR-302e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-40 1.32E-36 7.04E-39 6.46E-38 109 1817 "ABAT,ACER3,TMEM74,MBP,ACTN2,MEG3,MDM4,CSMD3,RTN1,SLITRK1,WAC,GRAMD1B,TMEM156,TOMM40L,HOGA1,TESK2,LRRTM4,LINC00461,PLA2G6,LRRC7,MOBP,SOX6,ERICH3,USP28,PPFIA1,ANXA7,SESN3,APC,SHTN1,AQP4,SLC1A6,URGCP,BCO1,SLC6A9,ARFGAP2,SLC8A3,CCDC88A,DACH2,CAPRIN2,MTR,ASTN1,SMARCE1,PHYHIPL,ATP2B2,PALLD,USP33,WDTC1,SOX1,ZCCHC24,FXYD6,NPAS3,ERBIN,ADHFE1,SEPT3,NFIA,ARHGEF7,LUZP2,DCLK2,KAZN,DDHD2,MYRF,ADGRL3,PRUNE2,FAM69C,PTBP2,GRIA2,RFFL,OPCML,DCLK1,PTGDR2,LGI1,PDE3B,PIRT,LINC01102,TMEFF2,HPCA,NLGN3,ZFYVE9,KIAA1549L,SLC25A27,IFFO1,NSD2,PTPA,RGS6,PRKCZ,DPYSL5,PLPPR5,SIRPA,CA10,CEP170,PLPPR4,CCDC3,KCNK2,PCDH15,WIPF2,SLC17A6,RAD52,PARP11,RALGDS,ATG16L1,C12orf4,RASGRF1,JMJD1C,ARHGEF10L,SH3GLB1,VWA5A,BSCL2,RCAN2,UEVLD" MicroRNA hsa-miR-3198:mirSVR_lowEffct hsa-miR-3198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.01E-40 1.63E-36 8.67E-39 7.95E-38 106 1721 "ADGRV1,RTKN,MDM4,CSMD3,ADAR,PLEKHG5,RXRG,GRAMD1B,DRAXIN,SNX32,LRRTM4,SCNN1D,KIAA1109,FHL1,MOG,ANK2,APBA2,NTNG1,ZNF365,MIER1,KIAA1614,MADD,PKNOX2,ARHGAP5,YPEL4,MT3,SLC14A1,DACH2,SCMH1,MTR,ATP1A2,EIF4G3,ATP2B2,GAD2,ZSWIM8,NMNAT2,ARPP21,EMC1,ADGRB2,C11orf87,STOX1,SLCO1C1,GLS,KAZN,PSRC1,KLHL4,PRUNE2,WSCD1,ACSL6,CACNB2,PRLHR,ZEB1,PTBP2,PCDHGA3,CAMK2G,VSTM2A,TGFBR3,MFSD2A,TLL2,NEURL1,PAH,CDK11B,REPS2,TPM4,PDE1A,PDE1C,PIRT,LINC01102,PDYN,ANO5,ZBED5,GDAP1L1,CADM1,NEGR1,CCSER2,PLXNB3,CABP1,PACSIN1,MFSD4A,CP,PPP3CB,DOCK7,PRKCG,CTNND1,SYTL2,DPYSL5,CADM2,CEP170,STMN4,PTPRE,PCDH15,KCNMA1,DLG2,HS3ST4,PLEKHB2,RALGDS,SLC25A41,RASGRF1,GNE,FAM13C,ARHGEF10L,PHC2,SFXN5,SLC4A10,ELAVL4,UEVLD" MicroRNA hsa-miR-561:PITA hsa-miR-561:PITA_TOP PITA 3.05E-40 1.65E-36 8.71E-39 7.99E-38 81 968 "MBP,ACTN2,CSMD3,SLITRK1,ADD3,SNX30,NLGN4X,GPR158,TESK2,SCN3A,SOX6,APC,CCDC80,SORBS1,API5,SLC7A14,ARHGAP5,SLC8A2,YPEL4,CCDC88A,DACH2,ASCL1,CSPG5,RCOR3,TMEM108,SNAP25,PHYHIPL,SOX1,MYT1L,SOX5,AHCYL1,NCAM1,RGL1,POPDC3,CAMTA1,CNTN2,ADGRL3,EML4,CAMK2A,CECR2,SYT6,BRSK2,PSD3,GRIA2,GRIA4,OMG,TJP1,TPM3,TUB,HNRNPK,HEPACAM,NRXN1,NRXN2,CCSER2,CNTN1,PRRX1,NSD2,FAT3,POU3F2,MED1,TENM4,RBPJ,PRKAB2,PKN2,CTNND2,LRRTM3,SIRPA,PTCH1,MAGI2,PTPRD,KCNK1,SNX27,DLG2,RAB5B,SLC17A6,ABI1,RBM12,SH3GLB1,SLC4A10,ELAVL4,RCAN2" MicroRNA hsa-miR-1246:mirSVR_lowEffct hsa-miR-1246:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-40 1.66E-36 8.71E-39 7.99E-38 103 1623 "ABAT,RCSD1,EYA1,ATAT1,LDLRAD3,SLC25A25,F3,KLRC4,SCN4B,UNC79,SLC30A10,MOBP,ASRGL1,ANK1,FOLH1,ITSN1,SH3GL2,SHTN1,SLC7A14,DACH2,PDE8B,SPHKAP,ASTN1,SNAP25,ATM,ATP1A2,ZCCHC24,ENKUR,KIF1B,FXYD6,NFASC,C11orf87,ADHFE1,NEUROD1,NFIA,ZNF638,GPM6B,ACSL6,CACNA1E,VWC2,LRIT2,GRID1,TGFBR3,KCNK10,REPS2,CDC42,CDH8,LGI1,PDE2A,PDE3B,PIRT,ZMYND8,BEST3,ANO5,PFKFB3,CHRM1,NLGN3,CCSER2,PLXNB3,PMP2,NECAB2,SPATA6,SNCAIP,PPP3CB,RGS6,VCAN,PRKACB,PKN2,USP54,CTNND2,NRSN1,MAPK8,TOX,ANKS1B,LRRTM3,PTHLH,CADM2,HP1BP3,CSDE1,ZC3H11A,PTPRD,KCNA6,RABGAP1L,KCNK1,KCNK2,KCNMA1,DLG3,RAB5B,TMEM255A,FAM66C,PARP11,RALGDS,DBX2,DTNA,PAK5,RFX5,RGR,SSPN,ARHGAP12,RAVER2,C2orf80,EN2,TMEM100" MicroRNA hsa-miR-4309:mirSVR_lowEffct hsa-miR-4309:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-40 1.69E-36 8.82E-39 8.09E-38 102 1591 "ADGRV1,RTKN,MDM4,ADAR,PLEKHG5,RXRG,GRAMD1B,DRAXIN,SNX32,HOGA1,LRRTM4,SCNN1D,KIAA1109,FHL1,MOG,ERICH3,ANK2,APBA2,ZNF365,MIER1,KIAA1614,MADD,PKNOX2,ARHGAP5,YPEL4,SLC14A1,SCMH1,MTR,ATP1A2,EIF4G3,ATP2B2,GAD2,ZSWIM8,NMNAT2,ARPP21,EMC1,ADAM15,ADGRB2,NFASC,STOX1,GLS,KAZN,PSRC1,KLHL4,PRUNE2,WSCD1,ACSL6,CACNB2,ZEB1,PTBP2,PCDHGA3,CAMK2G,VSTM2A,TGFBR3,MFSD2A,TLL2,NEURL1,PAH,REPS2,TPM4,PDE1A,PDE1C,PIRT,LINC01102,PDYN,ANO5,CHGA,ZBED5,CADM1,NEGR1,CCSER2,FTO,PACSIN1,MFSD4A,CP,PPP3CB,PRKCG,CTNND1,EDRF1,SYTL2,DPYSL5,CADM2,CEP170,STMN4,PTPRE,PCDH15,KCNMA1,DLG2,HS3ST4,PLEKHB2,RALGDS,SLC25A41,SLC25A18,RASGRF1,GNE,FAM13C,ARHGEF10L,PHC2,SFXN5,SLC4A10,ELAVL4,UEVLD" MicroRNA hsa-miR-410:mirSVR_highEffct hsa-miR-410:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.23E-40 1.75E-36 9.10E-39 8.35E-38 108 1789 "RABEPK,EPS8,SYT9,ARID1A,WLS,SLC25A25,CSMD3,SORCS1,GRAMD1B,HOGA1,LRRTM4,LRRC7,BCAR3,ELMOD1,AMPH,FOLH1,PPFIA1,NTNG1,GPAM,SLITRK3,NLGN1,SHTN1,ZNF365,MIER1,RUFY2,MSR1,LRRC55,ARHGAP5,SLC14A1,DACH2,ASPH,TMEM108,PHYHIPL,USP33,WDTC1,CADM3,NMNAT2,ARPP21,NAP1L2,SPART,NCAM1,C11orf87,NDUFA5,KIRREL3,NEUROD1,RND1,AJAP1,SLCO1C1,GLS,ZNF638,LUZP2,CAMTA1,ADGRL3,TCF12,PTBP2,NUDT21,GRIA1,GRIA2,GRIA4,LEFTY2,HPS5,PCDH8,CDH10,PCSK2,MAGI1,PDE3B,CIART,BEST3,HMGB1,TMEFF2,UBTF,CCSER2,VAV2,SPATA6,POU3F2,PPP2R5C,SNCAIP,OSBPL3,PHACTR3,FMN2,CTNND1,PROX1,FGFR1OP2,MASP1,PLPPR5,LRRTM3,PTCH1,DNAJC6,LRP8,CSDE1,ZC3H11A,OCIAD1,C1orf109,PTPRZ1,KCNMA1,DLG2,ATG16L1,DBX2,DTNA,RTN4,ABCC9,TTLL7,RLBP1,SEC61A2,ABI2,EN2,RPE65,TMEM100" MicroRNA hsa-miR-526b*:mirSVR_highEffct hsa-miR-526b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.29E-40 1.78E-36 9.22E-39 8.46E-38 102 1592 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASTN1,ATP1A2,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,SPART,LMO3,SMOC1,ERBIN,NELL1,RGL1,ADHFE1,GLS,DCLK2,CAMTA1,CAMSAP2,ADGRL3,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,BEST3,CHGA,JAM2,ZFYVE9,UBTF,CCSER2,SLC25A27,BTF3L4,PRRX1,ACBD5,CNRIP1,CRLS1,PPP3CB,FEZ2,CHD5,PRKACB,DOCK7,PKN2,NRSN1,PSD,ANKS1B,SIRPA,ITGAV,CA10,PTHLH,CADM2,PRTFDC1,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PLPPR4,PTPRO,KCNJ10,KCNK1,PCDH15,KCNMA1,OLIG1,RAB5B,TMEM255A,ATG16L1,FAM13C,DTNA,PAK5,ABCC9,ZYG11B,SFXN5,SLC39A12,ARHGAP12,RAVER2,TMEM100,UEVLD" MicroRNA hsa-miR-16-1*:mirSVR_lowEffct hsa-miR-16-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.33E-40 1.80E-36 9.30E-39 8.53E-38 113 1960 "RPL38,APC2,LGR4,ATAT1,WLS,RTKN,CSMD3,KLHL32,RTN1,KLRC4,AMER2,LRRC7,SEMA6A,BCAR3,SLC30A10,MOBP,SELL,ANK3,ITSN1,PPM1E,DOCK10,CCDC80,SLITRK3,CLSTN1,RUFY2,MSR1,ARHGAP5,SLC8A3,CCDC88A,SHANK2,DACH2,CSPG5,SLCO1A2,MTR,CCDC181,PHYHIPL,PALLD,SON,MYBPC1,TNIK,KIF21B,TTLL9,KIF1B,LMO3,C11orf87,ALDH1L1,SMOC1,DCAF5,ADHFE1,PCDH11X,SYT4,DCLK2,DDHD2,ADGRL3,ANO4,AZIN2,GRIA1,GRIA2,GRIK2,LINC00839,SPX,AIFM1,DAAM2,TPM3,PCSK2,MAGI1,PDE3B,HMGB1,PFKFB3,CASC2,TMEFF2,KIAA1549L,NMT2,CCSER2,OPALIN,DNAJC12,SLC25A27,PRRX1,SLC36A4,ACBD5,MFSD4A,TENM4,MICAL2,OSBPL3,VCAN,NCAN,USP54,PUM1,TOX,PLPPR5,PSMD13,PRDM2,PRTFDC1,CSDE1,AK5,CAB39L,TMEM255A,FAM66C,PARP11,C12orf4,RASGRF1,FAM13C,NUP214,JMJD1C,INSYN2,SSPN,RBM12,SH3GLB1,VWA5A,RAVER2,TMEM100,EPB41L1,EPB41L2" MicroRNA hsa-miR-3157:mirSVR_lowEffct hsa-miR-3157:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.63E-40 1.97E-36 1.01E-38 9.25E-38 111 1893 "SDE2,ZFYVE27,MBP,CNTNAP3,SYT9,IL17D,CSMD2,MDM4,RTN1,ADCY2,SORCS1,DRAXIN,TOMM40L,HOGA1,LINC00461,KIAA1109,FGF14,SH3GL2,NTNG1,MAGI3,GPAM,SORBS1,BCAS1,ZNF365,BCO1,LRRC55,SLC6A9,ARHGAP5,MT3,TMEM108,ATP1A2,ATP2B2,WDTC1,AHCYL1,JPH4,LHFPL4,ADAM15,DNER,NPAS3,SPART,NFASC,LMO3,ACSBG1,NFIA,LUZP2,DCLK2,ANO4,PRUNE2,DDR1,CACNB2,ZEB1,AZIN2,TMEM151B,OPCML,LINC00839,CRB1,P2RX7,GUCY1A1,AIFM1,PCDH9,DCLK1,SEZ6L,LGI1,TPM3,HMGB1,CAMKV,SEMA5B,NEGR1,A2ML1,FLRT1,BEST1,BTF3L4,IFFO1,NXPH1,RGS6,KCNT2,OSBPL3,ATRNL1,NCAN,RIMS4,RBPJ,PRKAB2,FMN2,CMTM5,CTNND2,MAPK10,PROX1,TOX,SPIRE1,SYNC,PSMD13,PMEPA1,BDNF-AS,PTHLH,CADM2,CNIH3,COPS7A,PTPRE,PTPRO,SRGAP3,KCNJ9,KCNK2,PEX5,PARP11,ATN1,SLC6A15,ARHGEF10L,PHC2,RPRD1A,SLC4A10,SEZ6" MicroRNA hsa-miR-618:mirSVR_lowEffct hsa-miR-618:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-40 1.98E-36 1.01E-38 9.29E-38 102 1594 "SDE2,ABAT,PRR5L,CNTNAP3,SYT9,IL17D,ECSIT,LDLRAD3,ADAR,F3,GALNT13,BCAR3,UNC79,HPCAL4,SOX6,CDC42BPA,PPFIA1,MAGI3,SHTN1,ZNF365,SLC1A7,RUFY2,MSR1,LRRC55,DACH2,SLCO1A2,ASPH,MTR,RCOR3,EIF4G3,MYT1L,CAB39,NMNAT2,EMC1,NFASC,NDUFA5,ABCC8,VAMP1,ZNF638,LUZP2,DCLK2,KAZN,UNC5D,ADGRL3,TMEM136,KLHL4,ATF7,CACNA1E,ZEB1,TCF12,AZIN2,PTBP2,SYT6,GRIA2,GRID1,GPR88,TGFBR3,CELF3,ZFP91,REPS2,CDC42,TNR,PADI2,CDH8,LGI1,TPD52,PCSK2,PIRT,DUSP26,ANLN,NMT2,PACSIN1,POU3F2,CHD1L,PNKD,PPP2R5C,SNCAIP,FMN2,ECE2,NOS1AP,ANKS1B,SPIRE1,SYNC,SIRPA,PTCH1,HP1BP3,COPS7A,OLFM3,CDH20,PTPRZ1,KCNJ10,DLG2,TMEM255A,FAM66C,FAM13C,ARHGEF10L,SSPN,SH3GLB1,ABI2,FGFBP3,YY1AP1,C2orf80" MicroRNA hsa-miR-190:mirSVR_lowEffct hsa-miR-190:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-40 2.01E-36 1.02E-38 9.35E-38 105 1692 "RABEPK,EPS8,PRR5L,SYT9,ADGRV1,EYA1,CSMD3,ADCY2,KLRC4,GPR158,BBOX1,SLC30A10,MOBP,ANK3,ANXA7,DOCK10,NTNG1,MAGI3,SLITRK3,ST3GAL3,JAKMIP3,SLC8A3,SHANK2,SLCO1A2,SPHKAP,SLIT1,ASPH,SORCS3,SMARCE1,TMEM108,MEGF11,SOX5,KIF1B,NAP1L2,NCAM1,C11orf87,CLASP2,STOX1,DCAF5,AJAP1,SLCO1C1,NFIA,NHLH1,ADGRL3,LILRA1,ZEB1,GPR19,CECR2,GRIA1,GRIN1,GPR88,OLR1,OMG,GUCY1A1,MAEL,DCLK1,LGI1,PIRT,HMGB1,CHGA,CHRM1,TUB,TMEFF2,PIK3CD,A2ML1,CNTN1,MEAF6,NXPH1,POU3F2,SF1,SNCAIP,RGS6,KCNT2,SDC3,PUM1,ZNF385B,PLPPR1,JAKMIP2,CADM2,HP1BP3,LRP8,BLOC1S6,PTPRE,PLPPR4,NTM,KCNJ10,KCNK1,KCNMA1,PEX5,KIF2A,KLRC2,DNM2,PLEKHB2,GNE,RTN4,ABCC9,SLC6A15,JMJD1C,RGS7,FAM135B,TTLL7,SYT15,SLC39A12,SLC4A10,EPB41" MicroRNA hsa-miR-105:mirSVR_highEffct hsa-miR-105:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.98E-40 2.15E-36 1.09E-38 9.97E-38 97 1437 "ACER3,LDLRAD3,WLS,CLIP1,SLITRK1,WAC,SORCS1,SLC44A5,TESK2,FHL1,SELL,SFPQ,PPFIA1,APBA2,GPAM,TACC2,API5,PAAF1,MSR1,SLC8A3,CCDC88A,ASPH,MTR,CAB39,KIF1B,NASP,NDUFA5,ZNF302,RND1,ARHGEF7,GLS,DCLK2,GNAS,CAMTA1,CAMSAP2,MMD2,ZEB1,CAMK2G,VSTM2A,GRIA2,GRIA4,GRID1,LINC00839,PTPN5,USP2,INA,TJP1,TLL2,ATG4C,MAEL,HPS5,PCDH9,CDH8,MAGI1,PDE1A,CIART,BEST3,HMGB1,HNRNPK,TMEFF2,NRXN1,A2ML1,TJP2,ST8SIA5,BTF3L4,CP,CHD1L,CRLS1,PPP3CB,PKN2,ARHGEF4,NRSN1,BRINP3,ZBTB16,TOX,SYTL2,PLPPR5,LRRTM3,DNAJC6,CA10,JAKMIP2,PTHLH,PRDM2,HP1BP3,LRP8,KCNMA1,DLG2,KIF2A,RAB5B,SLC17A6,PAK5,FAM135B,SSPN,RBM12,RPRD1A,FGFBP3,CBLN2" MicroRNA hsa-miR-3169:mirSVR_lowEffct hsa-miR-3169:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-40 2.22E-36 1.12E-38 1.03E-37 106 1727 "TMEM74,MBP,CNTNAP3,SYT9,SYNDIG1,ACTN2,ARID1A,GALNT13,SORCS1,FCGR1A,CHST15,TOMM40L,LRRTM4,LINC00461,FGF14,ASIC4,MOBP,MOG,ERICH3,ITSN1,SORBS1,ZNF365,SLC2A5,MSR1,MSRA,SLC6A9,SLC8A3,SPHKAP,ASPH,SCN3B,B4GALNT1,NPAS3,NCAM1,BCL2L2,ALDH1L1,STOX1,NCDN,NEUROD1,SEPT3,FAM168A,GNG4,MYRF,ADGRL3,WWC1,ANO4,ATF7,AZIN2,NUDT21,PCDHGA3,CAMK2G,TMEM151B,DDR2,GRIA4,GPR88,INA,P2RX7,TMEM257,DAAM2,MAEL,REPS2,TNS1,CDH10,ZMYND8,TMPRSS5,PFKFB3,ASIC3,PLEKHB1,CASC2,HNRNPK,TMEFF2,NEGR1,NMT2,FTO,C11orf49,MEAF6,CELF5,MFSD4A,FEZ1,NCAN,PRKAB2,FMN2,USP54,CTNND1,NOS1AP,GON4L,PLPPR5,HP1BP3,PTPRE,RABGAP1L,KCNK1,NAV2,CAB39L,DNM2,SLC17A6,ABI1,RASGRF1,DBX2,VANGL2,SIDT2,RBM12,SH3GLB1,CBLN2,SLC4A10,RPE65,RCAN2,BAALC" MicroRNA hsa-miR-188-3p:mirSVR_lowEffct hsa-miR-188-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.41E-40 2.39E-36 1.19E-38 1.09E-37 111 1897 "DPF1,RABEPK,MBP,RCSD1,MDM4,NDRG2,CLIP1,WAC,TUBB4A,FCGR1A,TOMM40L,SNX32,LINC00461,ASIC4,MOBP,FOXG1,SOX6,FOXM1,CNIH2,PPM1E,DGKZ,GPAM,NLGN1,PAAF1,SLC1A7,YPEL4,SLC8A3,MT3,SCMH1,CAPRIN2,ASPH,ALDH4A1,GABBR1,ZCCHC24,ZSWIM8,EMC1,ADAM15,GART,SPART,HEPN1,RGL1,GANAB,ARHGEF7,VAMP1,ASTN2,GNAS,CDK5R2,UNC5D,DDR1,CACNB2,TCF12,AZIN2,CECR2,AKNA,CYB561A3,PTPN5,TMEM25,INA,TLL2,KCNK10,MAEL,REPS2,HPS5,PADI2,ARHGAP19,TPM4,PDE2A,PDE3B,PIRT,TMPRSS5,CHI3L2,NLGN3,NMT2,TJP2,ST8SIA5,IFFO1,NSD2,MFSD4A,CRLS1,PTPA,RGS6,MICAL2,ATRNL1,PRKAB2,PSD,SPIRE1,PTCH1,PMEPA1,CNIH3,PLPPR4,SRGAP3,KCNJ9,KCNJ11,PCDH15,NKAIN1,HS3ST4,WIPF2,PID1,FAM66C,C12orf4,RAP1GAP,ABI1,DTNA,RFX5,INSYN2,ARHGEF10L,PHC2,TTLL7,GPR61,EPB41,SEZ6" MicroRNA hsa-miR-106a*:mirSVR_lowEffct hsa-miR-106a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.41E-40 2.39E-36 1.19E-38 1.09E-37 111 1897 "MBP,CNTNAP3,SYT9,LGR4,RCSD1,ATAT1,CSMD3,GRAMD1B,SLC44A5,SCN3A,LRRTM4,LRRC7,ASIC4,FOXG1,ANK3,PPFIA1,ITSN1,ANXA7,PPM1E,DOCK10,APC,CACHD1,SHTN1,MT3,SLC14A1,GPR153,SORCS3,KBTBD12,MYBPC1,SOX5,GAD2,ZSWIM8,NAP1L2,NPAS3,ADHFE1,NEUROD1,SEPT3,LUZP2,UNC5D,TMEM136,ANO4,GPM6B,TCF12,NUDT21,EML4,OMG,USP2,CELF3,TMEM257,REPS2,PCDH9,LGI1,PCSK2,PDE1C,ANO5,CASC2,NRXN1,NOMO2,ANLN,SULT4A1,PMP2,P2RY12,SLC36A4,MFSD4A,POU3F2,CHD1L,SF1,RNF14,SNCAIP,OSBPL3,VCAN,PHACTR3,RBPJ,FMN2,PLPP4,NOS1AP,ANKS1B,ZNF385B,PTAFR,PTCH1,ITGAV,PTHLH,HP1BP3,COPS7A,KCNA1,KCNA4,PTPRD,PTPRZ1,KCNK2,KCNMA1,SNX27,DLG2,DLG3,KIF2A,KLRC2,PID1,SLC17A6,PARP11,GOPC,DSCAM,RASGRF1,DTNA,PAK5,ZYG11B,RET,RGS7,ABI2,ARHGAP12,CBLN2,C2orf80,RPE65" MicroRNA hsa-miR-219-2-3p:mirSVR_lowEffct hsa-miR-219-2-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.66E-40 2.52E-36 1.25E-38 1.15E-37 109 1830 "RABEPK,EPS8,EYA1,ARID1A,CSMD3,RTN1,CDC7,AMER2,FOXRED2,SLC44A5,SEMA6A,UNC79,MOBP,TRIM46,SGIP1,ANK3,SESN3,MAGI3,SORBS1,ST3GAL3,AQP4,SLC1A7,ARHGAP5,CAPRIN2,ATM,SNCB,NRG3,EIF4G3,SCN3B,SOX5,SOX10,GAD2,NEK6,KIF1B,NFASC,DCAF5,NELL1,NEUROD1,SEPT3,ACSBG1,LUZP2,GNAS,CAMTA1,ADGRL3,CNDP1,KLHL4,CACNA1A,WSCD1,GPM6B,ACSL6,LILRA1,VXN,VSTM2A,AKNA,GRIA2,CRB1,P2RX7,TJP1,TLL2,TMEM257,CDC42,TNR,PCDH9,DCLK1,SEZ6L,LGI1,HMGB1,CASC2,NRXN1,CAMKV,CNTN1,MICAL1,P2RY12,CP,POU3F2,CRLS1,PPP2R5C,PPP3CB,MICAL2,OSBPL3,ATRNL1,USP54,CTNND2,FGFR1OP2,ANKS1B,ZNF385B,DNAJC6,CA10,PRDM2,PRTFDC1,BLOC1S6,OCIAD1,KCNA6,KCNJ10,KCNK2,DLG2,PID1,SLC17A6,FAM13C,JMJD1C,INSYN2,ATL1,ZNF248,TTLL7,SFXN5,SLC39A12,CBLN2,ELAVL4,RPE65" MicroRNA hsa-miR-3126-5p:mirSVR_lowEffct hsa-miR-3126-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.35E-40 2.90E-36 1.43E-38 1.31E-37 105 1699 "ZFYVE27,CDHR1,MEG3,FAM43B,ATAT1,WLS,MDM4,ADAR,PLEKHG5,ADCY2,ADORA1,TUBB4A,HOGA1,SCN4B,KIAA1109,ASIC4,FHL1,GOLGA7B,ELMOD1,MOBP,ERICH3,ITSN1,PPM1E,GPAM,DGKD,NLGN1,MADD,LRRC55,ARFGAP2,DACH2,SLIT1,BRINP2,ASTN1,ALDH4A1,NRG3,EIF4G3,DKK3,WDTC1,KIF1B,SPART,NFASC,NCAM1,BCL2L2,GANAB,GLS,NHLH1,KAZN,UNC5D,ADGRL3,GPM6A,TCF7L2,DIRAS1,CAMK2A,CAMK2G,VXN,NUCB1,TMEM25,ZDHHC22,CD81,CDK11B,TNS1,RBFOX2,PDE3B,FNDC5,HMGB1,ANO5,CHRM1,CASC2,HEPACAM,UBTF,FADS2,PLXNB3,CELF5,SLC25A27,PACSIN1,NXPH1,CNRIP1,CRMP1,CRLS1,MICAL2,OSBPL3,ATRNL1,VCAN,PLPP4,PRKCZ,MAPK10,FGFR1OP2,PHYHIP,PRDM2,CEP170,CSDE1,SRGAP3,KCNJ10,DNAH9,KLRC3,FAM57B,DPP6,RASGRF1,ABCC9,SFXN5,SSPN,CACNG7,VWA5A,YY1AP1,EPB41L1" MicroRNA hsa-miR-146a:mirSVR_lowEffct hsa-miR-146a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.63E-40 3.05E-36 1.49E-38 1.36E-37 111 1902 "RABEPK,EPS8,ZFYVE27,ACER3,MAP6,CDHR1,DUSP27,RCSD1,ADGRV1,MRVI1,ATAT1,CSMD2,ARID1A,ADCY2,CHST15,GPR158,SNX32,LRRTM4,CDC42BPA,ANK2,ANXA7,MAGI3,DGKD,SHTN1,CLSTN1,RPH3A,BCO1,RUFY2,DNAH17,ASPH,RCOR3,ATM,NRG3,SCN3B,SOX10,GAD2,ZSWIM8,ENKUR,ADAM15,GART,NPAS3,SPART,SMOC1,GLS,NHLH1,DCLK2,NODAL,UNC5D,MMD2,TMEM136,GPM6A,GPM6B,B4GALNT4,GPR19,PCDHGA3,GRIA1,VWCE,TMEM257,DAAM2,PADI2,PCDH9,CDH8,DCLK1,SEZ6L,TPD52,PCSK2,PIRT,FNDC5,GPR37L1,ANO5,PFKFB3,CHRNB2,NLGN3,SERPINE2,CADM1,ANLN,OPALIN,CNTN1,MEAF6,CELF5,PRRX1,SLC36A4,NXPH1,CHD1L,SF1,RNF14,PPP2R5C,PPP3CB,OSBPL3,ATRNL1,PRKACB,ARHGEF4,ECE2,SYNC,PTAFR,CNIH3,PRDM2,LRP8,OLFM3,KCNA6,NAV2,DLG2,TMEM255A,RALGDS,C12orf4,DSCAM,ZNF248,VANGL2,SEC61A2,FGFBP3,SEZ6" MicroRNA hsa-miR-17:mirSVR_highEffct hsa-miR-17:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.66E-40 3.06E-36 1.49E-38 1.36E-37 102 1602 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASPH,ASTN1,ATP1A2,EIF4G3,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,NPAS3,SPART,LMO3,SMOC1,ERBIN,NELL1,RGL1,ADHFE1,FAM168A,ARHGEF7,DCLK2,CAMTA1,CAMSAP2,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,PRMT8,BEST3,CASC2,MS4A7,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,SPATA6,ACBD5,CNRIP1,PPP3CB,FEZ2,CHD5,PRKACB,PKN2,NRSN1,PSD,ANKS1B,TOMM20,SIRPA,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PTPRO,RABGAP1L,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,TMEM255A,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,SFXN5,EFNA3,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-106a:mirSVR_highEffct hsa-miR-106a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.66E-40 3.06E-36 1.49E-38 1.36E-37 102 1602 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASPH,ASTN1,ATP1A2,EIF4G3,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,NPAS3,SPART,LMO3,SMOC1,ERBIN,NELL1,RGL1,ADHFE1,FAM168A,ARHGEF7,DCLK2,CAMTA1,CAMSAP2,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,PRMT8,BEST3,CASC2,MS4A7,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,SPATA6,ACBD5,CNRIP1,PPP3CB,FEZ2,CHD5,PRKACB,PKN2,NRSN1,PSD,ANKS1B,TOMM20,SIRPA,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PTPRO,RABGAP1L,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,TMEM255A,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,SFXN5,EFNA3,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-297:mirSVR_highEffct hsa-miR-297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.31E-40 3.42E-36 1.65E-38 1.51E-37 93 1322 "ACLY,SYNDIG1,MEG3,CSMD3,CLIP1,KLHL32,ADD3,CDC7,LRRTM4,LINC00461,KIAA1109,LRRC7,ERICH3,CDC42BPA,ANK3,ANXA7,NTNG1,API5,ZNF365,MIER1,MSR1,MSRA,CCDC88A,SCG3,SMARCE1,RCOR3,SNAP25,EIF4G3,SOX5,KIF21B,CADM3,ILDR2,NPAS3,NELL1,ADHFE1,NEUROD1,ARHGEF7,ADGRL3,ANO4,GPM6A,GPM6B,ATF7,TCF7L2,TCF12,GRIA4,GRIK2,OLR1,CCKBR,CRB1,GUCY1A2,PCSK2,PDE3B,PRMT8,BEST3,CASC2,NRXN1,A2ML1,SLC25A27,BEST1,SPATA6,NSD2,CNRIP1,CP,PPP2R5C,NKAIN4,OSBPL3,ATRNL1,NCAN,DOCK7,PLD5,CTNND2,ANKS1B,TOMM20,PLPPR5,SYNC,PTAFR,CA10,BDNF-AS,CADM2,CNIH3,PRDM2,OLFM3,PTPRE,PCDH15,KIF2A,C12orf4,DBX2,SLC6A15,NUP214,RFX4,INSYN2,RNF220,ABI2" MicroRNA hsa-miR-19b:mirSVR_highEffct hsa-miR-19b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.35E-40 3.44E-36 1.65E-38 1.52E-37 99 1508 "PRR5L,MDM4,CSMD3,F3,CLIP1,RTN1,WAC,GRAMD1B,GPR158,TESK2,SCN3A,MOG,SOX6,CDC42BPA,ITSN1,ANXA7,SH3GL2,APBA2,DOCK10,SYBU,SHTN1,MIER1,BCO1,RUFY2,MSRA,CCDC88A,SLC14A1,SPHKAP,CAPRIN2,RCOR3,SNAP25,ATP1A2,GABBR1,USP33,SON,MYT1L,SOX5,CAB39,GAD2,NAP1L2,SPART,NDUFA5,SMOC1,RGL1,NEUROD1,FAM168A,GLS,KAZN,CAMTA1,CAMSAP2,PRUNE2,TCF12,SYT6,OMG,TGFBR3,MFSD2A,TLL2,ZFP91,PDE1C,PDE3B,TUB,TMEFF2,ZFYVE9,CCSER2,BTF3L4,ACBD5,POU3F2,SNCAIP,PPP3CB,MICAL2,ATRNL1,PRKACB,FMN2,PLPP4,PSD,ANKS1B,ZNF385B,PLPPR1,PMEPA1,CEP170,MAGI2,KCNA4,PTPRD,KCNK2,PCDH15,ATG16L1,DSCAM,FAM13C,DTNA,PAK5,ABCC9,RET,RFX4,INSYN2,SEC61A2,RPRD1A,ARHGAP12,CBLN2,ELAVL4" MicroRNA hsa-miR-590-3p:PITA hsa-miR-590-3p:PITA_TOP PITA 6.56E-40 3.55E-36 1.70E-38 1.56E-37 98 1477 "ABAT,ACER3,RTN3,EYA1,MDM4,CLIP1,KLHL32,GALNT13,ADD3,WAC,CDC7,LRRC7,FOXG1,SFPQ,SGIP1,ANK3,USP28,ITSN1,PPM1E,APC,GAS7,SLITRK3,TACC2,CACHD1,NLGN1,CLSTN1,AQP4,ARHGAP5,CCDC88A,SLN,RCOR3,SNAP25,FYN,PHYHIPL,ZCCHC24,SOX10,CAB39,SPART,ERBIN,SLCO1C1,PCDH11X,SYT4,CAMTA1,CAMSAP2,ADGRL3,GOLGB1,ANO4,TBX15,WSCD1,PTBP2,NUDT21,PSD3,GRIA2,GRIA4,INA,GUCY1A1,CDC42,PCDH9,ARHGAP19,PCSK2,MAGI1,HNRNPK,SERPINE2,PMP2,MEAF6,NSD2,FAT3,POU3F2,MED1,KCNT2,OSBPL3,FMN2,RAB39A,PKN2,CTNND2,KIAA0408,BRINP3,SYTL2,LRRTM3,DNAJC6,ITGAV,CADM2,CEP170,ARNT2,KCNMA1,SNX27,DLG2,TMEM255A,SLC17A6,DBX2,PAK5,SLC6A15,RET,JMJD1C,TTLL7,RBM12,SH3GLB1,EPB41L1" MicroRNA hsa-miR-21:mirSVR_highEffct hsa-miR-21:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.71E-40 3.63E-36 1.73E-38 1.59E-37 84 1061 "ABAT,PRR5L,F3,ADCY2,NLGN4X,TESK2,LINC00461,KIAA1109,FGF1,SLC30A10,MOBP,SGIP1,ANK3,ITSN1,SORBS1,ZNF365,MIER1,ARFGAP2,SLC8A3,NSG2,RCOR3,SNAP25,MEGF11,USP33,B3GALT2,SOX5,ARPP21,SALL3,NEK6,CLASP2,ARHGEF7,VAMP1,CAMTA1,PSRC1,FAM69C,PTBP2,GRIA4,RFFL,CYB561A3,TIE1,RBFOX2,PDE4B,BEST3,HPSE2,ANO5,CASC2,HNRNPK,CADM1,NEGR1,DNAJC12,CNTN1,CELF5,BTF3L4,PACSIN1,SNCAIP,KCNT2,FEZ2,OSBPL3,ATRNL1,RBPJ,DZIP3,MAPK10,ZBTB16,ANKS1B,DNAJC6,PRTFDC1,COPS7A,MAGI2,KCNA2,OLFM3,C1orf109,CAB39L,HS3ST4,DNM2,DTNA,RTN4,ABCC9,NUP214,SLC39A12,SSPN,RPRD1A,RAVER2,SLC4A10,RCAN2" MicroRNA hsa-miR-4302:mirSVR_lowEffct hsa-miR-4302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.13E-40 3.86E-36 1.83E-38 1.68E-37 113 1976 "ACHE,CDHR1,SYT9,CEND1,LDLRAD3,MDM4,CSMD3,NDRG2,CLIP1,SLITRK1,SORCS1,HOGA1,TESK2,SCN3A,DISP3,SEMA6A,ASIC4,BCAR3,MOG,SOX6,TRIM46,ERICH3,ANK3,PPFIA1,NTNG1,CCDC80,GPAM,TACC2,ST3GAL3,ARFGAP2,DACH2,SCMH1,ASCL1,ASPH,BRINP2,SORCS3,ASTN1,RCOR3,NRG3,ATP2B2,PALLD,GABBR1,SOX5,SOX10,ZSWIM8,ARPP21,ADGRB2,LMO3,BCL2L2,ALDH1L1,ADHFE1,AJAP1,CAMTA1,CAMSAP2,MYRF,GOLGB1,KLHL4,ANO4,DDR1,ZEB1,TMEM151B,GRIA2,GRID1,GPR88,OMG,CRB1,LEFTY2,TJP1,HPS5,TNR,LGI1,TPD52,PIRT,PFKFB3,CASC2,CADM1,A2ML1,CCDC136,NECAB2,NSD2,CRLS1,RGS6,MICAL2,PLD5,CTNND2,PUM1,RIMS3,GON4L,SYNC,PTCH1,BDNF-AS,PTHLH,MAGI2,OLFM3,PLPPR4,PARD6A,RABGAP1L,DLG3,RAB5B,TMEM255A,SLC25A48,FAM57B,RALGDS,DTNA,ABCC9,SLC6A15,FAM135B,ARHGEF10L,SYT15,RNF220,SLC4A10,EN2,EPB41" MicroRNA hsa-miR-190b:mirSVR_lowEffct hsa-miR-190b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.20E-40 3.90E-36 1.84E-38 1.69E-37 103 1639 "EPS8,PRR5L,ACER3,ADGRV1,EYA1,CSMD3,ADAR,ADCY2,KLRC4,GPR158,BBOX1,ELMOD1,SLC30A10,MOBP,ANK3,ANXA7,DOCK10,NTNG1,MAGI3,SLITRK3,ST3GAL3,JAKMIP3,RUFY2,SLC8A3,SHANK2,SLCO1A2,SLIT1,ASPH,SORCS3,SMARCE1,TMEM108,ATM,MEGF11,SOX5,KIF1B,NAP1L2,NCAM1,C11orf87,CLASP2,STOX1,DCAF5,AJAP1,SLCO1C1,NHLH1,ADGRL3,VWC2,LILRA1,GPR19,CECR2,GRIA1,GRIN1,GPR88,OLR1,OMG,SHISA7,P2RX7,GUCY1A1,MAEL,DCLK1,LGI1,PIRT,CHGA,TUB,TMEFF2,PIK3CD,NMT2,FTO,CNTN1,MEAF6,NXPH1,POU3F2,SF1,SNCAIP,PPP3CB,RGS6,KCNT2,ATRNL1,SDC3,PUM1,ZNF385B,PLPPR1,JAKMIP2,CADM2,HP1BP3,LRP8,CEP170,PTPRE,NTM,KCNJ10,KCNK1,PEX5,DNM2,PLEKHB2,RTN4,SLC6A15,JMJD1C,RGS7,FAM135B,TTLL7,SYT15,SLC39A12,SLC4A10,EPB41" MicroRNA hsa-miR-485-3p:mirSVR_highEffct hsa-miR-485-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.58E-40 4.10E-36 1.93E-38 1.77E-37 93 1325 "SDE2,LGR4,CSMD2,ARID1A,WLS,MDM4,KLHL32,WAC,SORCS1,AGT,LINC00461,FGF1,LRRC7,ASRGL1,SGIP1,ANK3,ITSN1,NTNG1,CCDC80,GPAM,API5,MIER1,RUFY2,MSR1,LRRC55,YPEL4,LGI3,ASTN1,SMARCE1,TMEM108,MEGF11,KIF21B,GAD2,KIF1B,C11orf87,ZNF302,ZNF638,GNAS,TBX15,GPM6A,FAM69C,TCF7L2,ZEB1,CECR2,GRIA2,GRIA4,GRID1,GRIK2,AIFM1,REPS2,MAGI1,ZNF384,CHGA,TMEFF2,NRXN1,NEGR1,ST8SIA5,PMP2,PRRX1,SPATA6,PACSIN1,NSD2,NXPH1,ATRNL1,VCAN,PRKAB2,DOCK7,PROX1,ANKS1B,PLPPR1,PRDM2,CEP170,MAGI2,BLOC1S6,ZC3H11A,PTPRD,SMG7,KCNC1,NTM,RABGAP1L,KCNK2,KCNMA1,PEX5,HS3ST4,TMEM255A,DBX2,SLC6A15,RGS7,ARHGEF10L,RNF220,SSPN,EPB41L2,BAALC" MicroRNA hsa-miR-431:mirSVR_lowEffct hsa-miR-431:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.40E-40 4.55E-36 2.13E-38 1.95E-37 101 1577 "C1orf194,SYNDIG1,FAM43B,MDM4,KLHL32,TMEM156,SNX32,TESK2,FGF14,ELMOD1,MOBP,PDZD4,ITSN1,PKP4,APC,SORBS1,MADD,SLC14A1,CGREF1,DDX25,ASTN1,SMARCE1,ADGRA1,ATM,NRG3,CAB39,SALL3,NFASC,ALDH1L1,NCDN,INKA2,GLS,PCDH11X,ZNF638,POPDC3,ANO4,TBX15,WSCD1,ACSL6,CLEC9A,TCF12,DIRAS1,CAMK2G,VSTM2A,BRSK2,GRIA1,GRIA2,GRIA4,GRIK2,OLR1,GUCY1A1,TJP1,ZFP91,REPS2,PCDH8,IGFN1,HMGB1,PLEKHB1,HNRNPK,NLGN3,A2ML1,CCSER2,DNAJC12,VAV2,POU3F2,CHD1L,KCNT2,FEZ1,PRKACB,USP54,ANKS1B,GON4L,BDNF-AS,ELMO1,CEP170,OLFM3,KCNA4,SMG7,SV2A,NTM,KCNJ10,TMCC2,CCDC3,DLG2,DNAH9,TMEM255A,RALGDS,SUSD4,ATN1,DSCAM,DBX2,PAK5,ABCC9,ZYG11B,NUP214,RFX4,ABI2,RPE65,EPB41,EPB41L1,BAALC" MicroRNA hsa-miR-20b:mirSVR_highEffct hsa-miR-20b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.70E-40 5.25E-36 2.44E-38 2.24E-37 102 1612 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASPH,BRINP2,ASTN1,ATP1A2,EIF4G3,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,SPART,LMO3,SMOC1,ERBIN,RGL1,ADHFE1,ARHGEF7,DCLK2,CAMTA1,CAMSAP2,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,PRMT8,BEST3,CASC2,MS4A7,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,ACBD5,CNRIP1,PPP3CB,FEZ2,CHD5,PRKACB,DOCK7,PKN2,USP54,NRSN1,PSD,ANKS1B,TOMM20,SIRPA,ITGAV,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PTPRO,RABGAP1L,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,TMEM255A,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,RFX4,SFXN5,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-338-3p:mirSVR_lowEffct hsa-miR-338-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-39 5.44E-36 2.52E-38 2.31E-37 111 1914 "MAP6,RBM10,SYT9,RCSD1,GALNT13,SEMA6A,PDZD4,ITSN1,SH3GL2,PPM1E,APBA2,APC,NTNG1,ST3GAL3,SHTN1,ZNF365,SFMBT2,MSR1,CCDC88A,CGREF1,SPHKAP,ASPH,ASTN1,SON,CADM3,CAB39,NMNAT2,ARPP21,NEK6,KIF1B,GART,NPAS3,NFASC,SMOC1,NELL1,ASTN2,KAZN,CAMTA1,GNG4,CAMSAP2,UNC5D,TMEM136,ANO4,PRUNE2,WSCD1,GPM6A,GPM6B,CACNA1E,VWC2,TCF7L2,PTBP2,VXN,RFFL,GRIK2,CRB1,LEFTY2,TGFBR3,MFSD2A,TLL2,TNFRSF1B,REPS2,CDC42,TPM3,ZNF384,PDE1A,PDE1C,FNDC5,ASIC3,HNRNPK,TMEFF2,CADM1,KIAA1549L,NRXN1,NEGR1,SULT4A1,BTF3L4,PRRX1,MFSD4A,CRMP1,MICAL2,RBPJ,DZIP3,RAB39A,FAM131B,MASP1,TOX,PSMD13,PMEPA1,ELMO1,CNIH3,BLOC1S6,OCIAD1,PTPRE,PLPPR4,PTPRO,SV2A,KCNJ10,KCNMA1,NKAIN1,TMEM255A,RAD52,RALGDS,C12orf4,SUSD4,NUP214,RET,ATL1,RBM12,VWA5A,SLC4A10,RCAN2" MicroRNA hsa-miR-4295:mirSVR_lowEffct hsa-miR-4295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-39 5.84E-36 2.69E-38 2.47E-37 102 1614 "RABEPK,PRR5L,ASIC1,LGR4,LDLRAD3,CSMD2,FCGR1A,CHST15,SCN4B,LRRC7,BCAR3,FOXG1,SELL,ITSN1,DOCK10,TACC2,SHTN1,ASCL1,SCG3,RCOR3,ATM,ATP1A2,SON,B3GALT2,KIF21B,CAB39,EMC1,DNER,NAP1L2,NDUFA5,RGL1,AJAP1,MLC1,VAMP1,SYT4,KAZN,TMEM136,ATF7,AZIN2,CECR2,TMEM151B,VSTM2A,NUMA1,GRIA2,GRIA4,OPCML,USP2,GUCY1A1,CELF3,KCNK10,DAAM2,TNFRSF1B,REPS2,HPS5,CDC42,RBFOX2,MAGI1,PDE1A,PDE4B,SCRG1,PFKFB3,MS4A7,TLX1,VAV2,SLC25A27,P2RY12,NSD2,FAT3,FEZ2,MICAL2,DZIP3,FMN2,SPIRE1,ZNF385B,LRRTM3,CSDE1,MAGI2,KCNA4,PTPRD,PTPRE,PTPRO,NTM,KCNJ10,KCNK1,PCDH15,SNX27,DLG2,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,FAM13C,DTNA,RTN4,BSDC1,RFX5,PIANP,SLC4A10,C2orf80,TMEM100,UEVLD" MicroRNA hsa-miR-497*:mirSVR_highEffct hsa-miR-497*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-39 6.17E-36 2.83E-38 2.60E-37 95 1393 "CNTNAP3,LGR4,RTN3,ARID1A,WLS,MDM4,KLHL32,RTN1,NLGN4X,GPR158,LINC00461,PDZD4,ANK2,ITSN1,BCAS1,USP16,ASCL1,SLCO1A2,SPHKAP,ASPH,SORCS3,SMARCE1,RCOR3,TMEM108,SNAP25,NRG3,ATP2B2,WDTC1,CAB39,ENKUR,SALL3,NPAS3,NELL1,KIRREL3,NEUROD1,GANAB,GLS,ZNF638,DDHD2,PSRC1,GPM6A,GPM6B,NPPA,ZEB1,SYT6,BRSK2,GRIA4,CYB561A3,GUCY1A2,NEURL1,PAH,CDH8,MAGI1,HMGB1,ANO5,HNRNPK,HPR,NMT2,A2ML1,PMP2,BTF3L4,MFSD4A,CP,MED1,SF1,ATRNL1,RBPJ,PRKACB,FMN2,PKN2,NRSN1,MASP1,PTHLH,ITIH2,CADM2,CEP170,OLFM3,OCIAD1,PTPRD,KCNA6,SMG7,PTPRE,PLPPR4,C1orf109,KLRC2,C12orf4,ABI1,GOPC,FAM13C,DBX2,DTNA,RTN4,SLC6A15,SSPN,RCAN2" MicroRNA hsa-miR-378:mirSVR_lowEffct hsa-miR-378:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-39 6.99E-36 3.19E-38 2.93E-37 103 1650 "SERPINA3,SYT9,SYNDIG1,MRVI1,ADAR,ADCY2,ADD3,ADORA1,SNX32,FGR,SOX6,CDC42BPA,APBA2,NTNG1,MAGI3,CCDC80,ZCCHC17,PAAF1,MSR1,LRRC55,PKNOX2,SLC8A2,SLC8A3,NSG2,SPHKAP,ASPH,KBTBD12,B3GAT1,NRG3,DKK3,WDTC1,ZCCHC24,CAB39,NMNAT2,NFASC,SMOC1,NELL1,ADHFE1,ZNF638,DCLK2,DDHD2,MMD2,ANO4,TBX15,GPM6B,TCF7L2,CLEC9A,TCF12,PTBP2,CAMK2A,VXN,SYT6,NUMA1,AKNA,GRIK2,GPR88,DAAM2,TNFRSF1B,PCDH9,DCLK1,IGFN1,LINC01102,GPR37L1,ANO5,CASC2,TUB,NLGN3,NMT2,CCSER2,CELF5,MFSD4A,CHD1L,SF1,CRLS1,SNCAIP,TENM4,PPP3CB,KCNT2,ATRNL1,NCAN,EDRF1,SIRPA,DNAJC6,KCNJ10,KCNK1,KCNN3,PEX5,DLG2,OLIG1,DNM2,SUSD4,RASGRF1,L1CAM,NUP214,RFX5,FAM135B,VANGL2,RNF220,SSPN,SLC4A10,EN2,EPB41,SEZ6" MicroRNA hsa-miR-20a:mirSVR_highEffct hsa-miR-20a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.37E-39 7.40E-36 3.36E-38 3.09E-37 104 1684 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,FOXG1,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASPH,ASTN1,ATP1A2,EIF4G3,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,SPART,LMO3,SMOC1,ERBIN,RGL1,ADHFE1,FAM168A,ARHGEF7,DCLK2,CAMTA1,CAMSAP2,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,PRMT8,BEST3,CHGA,CASC2,MS4A7,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,SPATA6,ACBD5,CNRIP1,PPP3CB,FEZ2,CHD5,PRKACB,PKN2,NRSN1,PSD,ANKS1B,SIRPA,ITGAV,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PTPRO,RABGAP1L,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,TMEM255A,ATG16L1,FAM13C,DTNA,PAK5,ABCC9,ZYG11B,RFX4,SFXN5,FGFBP3,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-193b:mirSVR_lowEffct hsa-miR-193b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-39 7.57E-36 3.42E-38 3.14E-37 88 1186 "ZFYVE27,ACER3,ASIC1,ACHE,ADGRV1,IL17D,RTKN,CLIP1,SORCS1,TESK2,DISP3,UNC79,SEMA6C,ANK3,ITSN1,APC,CCDC80,NLGN1,BCAS1,CLSTN1,ZNF365,RUFY2,LRRC55,YPEL4,CCDC88A,NSG2,EIF4G3,GABBR1,USP33,WDTC1,SOX5,ZSWIM8,NPAS3,NFASC,NCAM1,CLASP2,BCL2L2,SLCO1C1,C1QC,NODAL,CNTN2,TMEM136,TBX15,NUDT21,NUMA1,RFFL,OMG,CRB1,TGFBR3,DAAM2,MAEL,PADI2,PCDH9,PCSK2,PDYN,FNDC5,HMGB1,LRTM2,CASC2,KIAA1549L,CAMKV,CCSER2,TJP2,C11orf49,NXPH1,CHD1L,FEZ1,PRKACB,PRKCZ,NRSN1,FAM131B,ECE2,NOS1AP,ZNF385B,PTCH1,PTHLH,RGMA,CSDE1,PTPRE,KCNJ9,FAM66C,ZYG11B,RBM12,GPR61,ABI2,BSCL2,C2orf80,EN2" MicroRNA hsa-miR-3152:mirSVR_lowEffct hsa-miR-3152:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-39 8.70E-36 3.92E-38 3.59E-37 94 1368 "ACLY,PAQR6,MRVI1,SLITRK1,GALNT13,SORCS1,SEMA6A,FOXG1,ERICH3,PPFIA1,SESN3,APC,NTNG1,GPAM,SLITRK3,ZNF365,BCO1,RUFY2,LRRC55,PKNOX2,CCDC88A,DACH2,SCMH1,ASCL1,FYN,PHYHIPL,MEGF11,MYT1L,ENKUR,ARPP21,TTLL9,DNER,NPAS3,NCAM1,C11orf87,STOX1,NELL1,MLC1,ARHGEF7,VAMP1,PCDH11X,UNC5D,ADGRL3,GOLGB1,KLHL4,GPM6B,PTBP2,CAMK2G,VXN,GRIA4,OPCML,LEFTY2,INA,DAAM2,CDC42,C1orf94,PCDH9,PCSK2,PDE4B,ANO5,PFKFB3,TUB,NRXN1,NEGR1,PRRX1,NXPH1,MFSD4A,PNKD,SNCAIP,NCAN,PRKAB2,PRKACB,PLPP4,PLD5,ARHGEF4,ANKS1B,PTCH1,JAKMIP2,CSDE1,MAGI2,OLFM3,PTPRZ1,SRGAP3,KCNK2,TMEM255A,DNM2,FAM13C,DBX2,BSDC1,RGS10,VANGL2,RPRD1A,LPAR6,CBLN2" MicroRNA hsa-miR-519a:mirSVR_highEffct hsa-miR-519a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-39 8.73E-36 3.92E-38 3.59E-37 96 1430 "CNTNAP3,MDM4,F3,RTN1,GALNT13,GPR158,HOGA1,TESK2,SCN3A,LRRC7,FOXG1,MOG,ERICH3,USP28,ITSN1,SLITRK3,SYBU,API5,SHTN1,PAAF1,BCO1,RUFY2,MSR1,LRRC55,CCDC88A,NAXD,CAPRIN2,RCOR3,ATM,GABBR1,USP33,MYT1L,B3GALT2,SOX5,GAD2,B4GALNT1,ARPP21,SPART,C11orf87,CLASP2,SMOC1,ERBIN,NELL1,ADHFE1,NEUROD1,GLS,ZNF638,LUZP2,CAMTA1,CAMSAP2,MYRF,GRIA4,ADAMTS8,LINC00839,TGFBR3,MAEL,HPS5,PDE3B,BEST3,TLX1,ZFYVE9,CCSER2,BTF3L4,PMS2,NSD2,CRLS1,PPP3CB,CHD5,DOCK7,NRSN1,MASP1,PSD,ANKS1B,CA10,PTHLH,CSDE1,PLPPR4,KCNJ10,KCNK1,SNX27,CAB39L,RAB5B,PID1,SLC25A48,SLC17A6,ATG16L1,ABCC9,ZYG11B,RET,RFX5,SSPN,FGFBP3,ARHGAP12,RAVER2,C2orf80,UEVLD" MicroRNA hsa-miR-4287:mirSVR_lowEffct hsa-miR-4287:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-39 8.85E-36 3.95E-38 3.63E-37 106 1754 "TTYH1,SDE2,MAP6,MAPT,FAM43B,MRVI1,RTKN,KCNIP2,CLIP1,TOMM40L,HOGA1,SCN3A,SEMA6A,PDZD4,SGIP1,ANK1,USP28,ITSN1,APBA2,APBB1,TACC2,CACHD1,ST3GAL3,USP16,ZNF365,SLC1A7,SLC8A2,YPEL4,SLC14A1,ASTN1,KBTBD12,B3GAT1,ATM,ATP1A2,NRG3,SCN3B,WDTC1,JPH4,TTLL9,KIF1B,NFASC,BCL2L2,PHLDB1,GANAB,RND1,ZNF638,GNAS,CAMTA1,KLHL4,WSCD1,CACNA1E,CACNB2,GPR19,TCF12,NUMA1,OPCML,TMEM25,ZDHHC22,ZFP91,CDC42,PCDH9,RBFOX2,SEZ6L,ZNF384,IGFN1,PIRT,PDYN,ZMYND8,LRTM2,PFKFB3,CASC2,TMEFF2,TLX1,PIK3CD,CPT1C,MEAF6,SLC36A4,IFFO1,SF1,PTPA,FEZ1,PRKACB,DZIP3,NOS1AP,ZBTB16,ITGAV,JAKMIP2,PMEPA1,BDNF-AS,PRDM2,COPS7A,BLOC1S6,KCNA4,KCNJ9,KCNJ10,KCNMA1,DLG2,DLG3,DNAH9,RAB5B,BSDC1,USH1C,FAM135B,SEC61A2,VWA5A,ARHGAP12" MicroRNA hsa-miR-1303:mirSVR_highEffct hsa-miR-1303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-39 9.03E-36 4.01E-38 3.68E-37 93 1338 "SYT9,RCSD1,ACTN2,GALNT13,SORCS1,ADORA3,LRRTM4,FGF1,HPCAL4,FOXG1,ANK2,ANK3,PPM1E,NTNG1,MAGI3,TACC2,SYBU,API5,SHTN1,MIER1,KIAA1614,SLC8A3,CCDC88A,SPHKAP,DLL3,RCOR3,TMEM108,ATM,SON,WDTC1,SOX1,MYT1L,GAD2,NMNAT2,DNER,NCAM1,NDUFA5,DCAF5,SLCO1C1,ZNF638,DDHD2,CAMSAP2,UNC5D,KLHL4,ANO4,VWC2,DDR1,ZEB1,TCF12,PTBP2,TMEM151B,ATP13A2,LEFTY2,INA,P2RX7,TJP1,PCDH9,CDH10,RBFOX2,MAGI1,PDE1C,PDE2A,ST8SIA5,CNTN1,BTF3L4,POU3F2,RNF14,PPP3CB,MICAL2,ATRNL1,PRKACB,CALY,IGSF1,CTNND1,PUM1,WBP1L,SYTL2,ANKS1B,PTCH1,ITGAV,CADM2,ELMO1,PRDM2,MAGI2,STMN4,TMCC2,KCNMA1,DLG2,FAM13C,INSYN2,SEC61A2,EPB41L2,SEZ6" MicroRNA hsa-miR-1304:mirSVR_lowEffct hsa-miR-1304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-39 9.97E-36 4.41E-38 4.05E-37 102 1624 "SERPINA3,ZFYVE27,LDLRAD3,WLS,ADCY2,SLITRK1,SORCS1,ERMN,SNX30,FGF1,BCAR3,ELMOD1,HPCAL4,SOX6,SFPQ,CNIH2,SESN3,MAGI3,CCDC80,DGKD,BCAN,ST3GAL3,ZNF365,NSG2,DACH2,CGREF1,MTR,ASTN1,KBTBD12,B3GAT1,ATM,PHYHIPL,ATP2B2,SON,WDTC1,AHCYL1,NPAS3,BCL2L2,ABCC8,CAMTA1,UNC5D,PTBP2,EML4,CAMK2A,AKNA,GRIK3,TF,CRB1,CDC42,PCDH9,TPD52,ZMYND8,BEST3,PFKFB3,ASIC3,NRXN2,ANLN,A2ML1,OPALIN,PMP2,SLC25A27,BTF3L4,CHD1L,MED1,PNKD,PTPA,SNCAIP,OSBPL3,PLPP4,USP54,NRSN1,ZBTB16,ACY3,WBP1L,DPYSL5,SPIRE1,TOMM20,PSMD13,PTAFR,PTHLH,MAGI2,BLOC1S6,KCNA1,OLFM3,SV2A,SRGAP3,TMCC2,KCNK2,PEX5,WIPF2,RAB5B,TMEM255A,PLEKHB2,ATN1,DBX2,SLC6A15,CAMK1G,ARHGEF10L,SEC61A2,SH3GLB1,RAVER2,PLEKHO1" MicroRNA hsa-miR-323-3p:mirSVR_highEffct hsa-miR-323-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.94E-39 1.05E-35 4.64E-38 4.25E-37 91 1280 "LGR4,SORCS1,NLGN4X,SLC44A5,LRRTM4,CDC42BPA,ANK2,SESN3,APC,GPAM,SLITRK3,SHTN1,ZNF365,MIER1,MADD,RUFY2,SPHKAP,PHYHIPL,PALLD,USP33,MYT1L,GAD2,ARPP21,NEK6,KIF1B,NAP1L2,NPAS3,RAP1GAP2,LMO3,ZNF302,ERBIN,SLCO1C1,ARHGEF7,PCDH11X,SYT4,GNAS,CAMTA1,MMD2,ADGRL3,PTBP2,GRIA4,TMEM25,TJP1,ZFP91,PCDH8,CDH10,ARHGAP19,LGI1,PDE4B,PIRT,HNRNPK,TMEFF2,JAM2,NRXN1,PMP2,MED1,CRMP1,CRLS1,ATRNL1,RBPJ,PKN2,NRSN1,PUM1,TOX,ANKS1B,PLPPR5,ZNF385B,DNAJC6,HP1BP3,OLFM3,OCIAD1,PTPRZ1,NTM,PEX5,KIF2A,SLC25A48,SLC17A6,SUSD4,ABI1,RASGRF1,FAM13C,DTNA,SLC6A15,JMJD1C,ZNF248,LMO1,VWA5A,LPAR6,ELAVL4,SEZ6,BAALC" MicroRNA hsa-miR-30b:mirSVR_highEffct hsa-miR-30b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.11E-39 1.14E-35 5.01E-38 4.60E-37 110 1895 "MAP6,CDHR1,CNTNAP3,SYT9,RCSD1,ARID1A,CSMD3,RTN1,GALNT13,CDC7,FABP7,SORCS1,ERMN,FCGR1A,SCN3A,LINC00461,SLC30A10,FOXG1,ERICH3,SGIP1,ITSN1,DOCK10,APC,MAGI3,SORBS1,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,SMARCE1,RCOR3,NRG3,ATP2B2,SON,JPH4,KIF1B,NAP1L2,NPAS3,SPART,CLASP2,ERBIN,RGL1,GLS,SYT4,GNAS,DDHD2,CAMTA1,ADGRL3,ANO4,PRUNE2,CACNB2,GPR19,EML4,CECR2,GRIA2,RFFL,GRM3,OMG,CRB1,USP2,TMEM9,TLL2,CELF3,PCDH9,LGI1,MAGI1,PIRT,ZMYND8,MS4A7,NEGR1,PIK3CD,MICAL1,ACBD5,PNKD,OSBPL3,PRKACB,DOCK7,CTNND2,TOX,SPIRE1,TOMM20,LRRTM3,CA10,JAKMIP2,CEP170,CSDE1,MAGI2,BLOC1S6,PLPPR4,RABGAP1L,PARP11,RALGDS,PAK5,ABCC9,RGS7,ARHGEF10L,TTLL7,SEC61A2,RNF220,RPRD1A,RAVER2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-362-3p:mirSVR_lowEffct hsa-miR-362-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-39 1.28E-35 5.59E-38 5.13E-37 107 1795 "MEG3,FAM43B,ARID1A,RTKN,CSMD3,SEMA6A,MOBP,PKP4,APBA2,NTNG1,MAGI3,JAKMIP3,SHTN1,ARFGAP2,SLC8A3,NSG2,DACH2,CGREF1,SLCO1A2,SMARCE1,ATM,NRG3,PALLD,TNIK,SOX5,ZCCHC24,KIF21B,CADM3,GAD2,ZSWIM8,ADAM15,KIF1B,CPLX2,ADGRB2,NPAS3,NFASC,NCAM1,SMOC1,AJAP1,NFIA,NHLH1,CAMTA1,ADGRL3,ANO4,TBX15,PRUNE2,AZIN2,NUDT21,VXN,NUMA1,GRIA2,RFFL,GRIK2,CYB561A3,OPCML,MFSD2A,TIE1,TMEM9,ZFP91,CD81,CDH10,DCLK1,ARHGAP19,LGI1,PRMT8,CADM1,KIAA1549L,CAMKV,FAT3,NXPH1,POU3F2,CRLS1,RBPJ,DOCK7,DZIP3,FMN2,CTNND1,NOS1AP,PROX1,TOX,PLPPR5,PTCH1,PRDM2,HP1BP3,MED24,PTPRD,PLPPR4,SRGAP3,AK5,PCDH15,PEX5,CAB39L,KIF2A,WIPF2,PLEKHB2,FAM66C,DTNA,ABCC9,RGS7,VANGL2,RNF220,SLC39A12,RBM12,RPRD1A,EN2,EPB41L2,BAALC" MicroRNA hsa-miR-770-5p:mirSVR_lowEffct hsa-miR-770-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.56E-39 1.38E-35 6.02E-38 5.52E-37 96 1438 "ACER3,EYA1,CSMD2,MDM4,PLEKHG5,KLHL32,ADD3,TOMM40L,SNX32,FGF14,ASIC4,UNC79,ELMOD1,MOG,FOXM1,RASA3,PPFIA1,ITSN1,CCDC80,BCAN,PAAF1,ARHGAP5,SPHKAP,RCOR3,USP33,GAD2,SALL3,FXYD6,STOX1,ERBIN,RCOR2,NEUROD1,AJAP1,ZNF638,PSRC1,TMEM136,ANO4,GPM6B,CACNB2,ZEB1,PTBP2,CRB1,SPX,AIFM1,TMEM257,CDH8,LGI1,TPM3,FNDC5,CASC2,SEMA5B,NMT2,SULT4A1,BEST1,BTF3L4,NSD2,ACBD5,CNRIP1,MFSD4A,PPP3CB,NKAIN4,MICAL2,ATRNL1,NCAN,RBPJ,PRKCZ,CTNND1,CTNND2,ECE2,TOX,SPIRE1,LRRTM3,PTCH1,ELMO1,COPS7A,KCNA6,PTPRE,PLPPR4,NTM,AK5,RABGAP1L,KCNJ11,PYGM,TMEM255A,FAM57B,ATN1,GOPC,FAM13C,RTN4,ZYG11B,NUP214,RFX4,RFX5,ATL1,LMO1,ABI2" MicroRNA hsa-miR-4292:mirSVR_lowEffct hsa-miR-4292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.67E-39 1.44E-35 6.25E-38 5.74E-37 102 1631 "LOC100128239,ACER3,MAP6,ASIC1,SRARP,RTN3,ADAR,SORCS1,ERMN,GRAMD1B,SNX32,SEMA6A,FHL1,MOG,TRIM46,PPFIA1,SH3GL2,APBB1,DGKZ,GPAM,PAAF1,RPH3A,URGCP,MADD,SLC8A2,SLC8A3,DNAH17,RCOR3,C10orf105,TMEM151A,ATP1A2,PALLD,SCN3B,NMNAT2,ARPP21,ADGRB2,FXYD6,ALDH1L1,NCDN,HEPN1,RND1,AJAP1,ARHGEF7,KAZN,SEMA4A,PSRC1,ADGRL3,DDR1,NEU4,CACNB2,TMEM151B,BRSK2,GRIA4,CYB561A3,TGFBR3,PC,PTGDR2,RBFOX2,TPM3,MAGI1,IGFN1,PRMT8,ZMYND8,FNDC5,BEST3,CASC2,HPCA,SLC22A6,DLGAP3,GDAP1L1,KIAA1549L,OPALIN,TJP2,BEST1,MFSD4A,PTPA,RGS6,OSBPL3,PRKCG,ECE2,NOS1AP,PHYHIP,GON4L,PRDM2,COPS7A,MAGI2,KCNJ11,KCNMA1,DLG3,DNAH9,RALGDS,SLC25A18,PAK5,L1CAM,BSDC1,CRTAC1,VANGL2,RNF220,SFXN5,VWA5A,RPE65,SEZ6" MicroRNA hsa-miR-224*:mirSVR_highEffct hsa-miR-224*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.30E-39 1.78E-35 7.69E-38 7.06E-37 102 1635 "SDE2,ACER3,RTN3,MEG3,ADGRV1,SLC25A25,CLIP1,CHST15,GPR158,BCAR3,CDC42BPA,RASA3,CNIH2,PKP4,PPM1E,DOCK10,DGKD,SORBS1,SHTN1,RPH3A,RUFY2,ARHGAP5,CCDC88A,ASCL1,CSPG5,SMARCE1,RCOR3,SNAP25,NRG3,PHYHIPL,WDTC1,B3GALT2,AHCYL1,NMNAT2,DNER,NAP1L2,NCAM1,LMO3,NDUFA5,NEUROD1,GLS,ZNF638,CAMTA1,PRUNE2,GPM6A,GPM6B,ZEB1,CECR2,VXN,GRIA1,GPR88,TJP1,TMEM257,ZFP91,LGI1,TPM3,ZNF384,PDE3B,LINC01102,BEST3,HNRNPK,TLX1,CADM1,A2ML1,FLRT1,CNTN1,CELF5,PRRX1,SPATA6,ACBD5,SNCAIP,KCNT2,VCAN,RBPJ,PRKACB,DOCK7,RAB39A,USP54,FGFR1OP2,SYNC,LRP8,CSDE1,ZC3H11A,PTPRE,KCNK2,KCNN3,DLG2,CAB39L,KLRC3,ABI1,RASGRF1,FAM13C,DTNA,PAK5,ABCC9,SLC6A15,JMJD1C,RBM12,ABI2,RAVER2,SLC4A10,EPB41L2" MicroRNA hsa-miR-556-3p:mirSVR_lowEffct hsa-miR-556-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.52E-39 1.91E-35 8.18E-38 7.50E-37 108 1837 "RBM10,APC2,TMEM74,MBP,CNTNAP3,LGR4,ADGRV1,EYA1,CSMD2,ARID1A,RTN1,WAC,NLGN4X,FCGR1A,LRRTM4,BCAR3,SOX6,ANXA7,DOCK10,APC,NTNG1,GPAM,SLITRK3,NLGN1,SHTN1,CLSTN1,AQP4,RUFY2,MSR1,CCDC88A,ASPH,DDX25,SMARCE1,RCOR3,SNAP25,ATM,CADM3,B4GALNT1,SALL3,NCAM1,LMO3,BCL2L2,NEUROD1,LUZP2,CNDP1,GPM6A,ATF7,ACSL6,TCF12,PTBP2,TMEM151B,AKNA,CYB561A3,CRB1,ZFP91,DAAM2,REPS2,PCDH8,CDH8,TPM3,TPM4,MAGI1,PDE3B,LINC01102,SCRG1,PFKFB3,MS4A7,TMEFF2,TJP2,POU3F2,ETNPPL,SNCAIP,FEZ1,MICAL2,OSBPL3,RBPJ,DOCK7,ARHGEF4,MAPK10,TOX,ANKS1B,PLPPR5,TUBB2B,PTCH1,DNAJC6,BDNF-AS,HP1BP3,BLOC1S6,OLFM3,PTPRD,SMG7,SRGAP3,NTM,RABGAP1L,KCNMA1,SLC17A6,SLC6A15,RFX5,FAM135B,TTLL7,RLBP1,SLC39A12,SH3GLB1,ARHGAP12,ELAVL3,TMEM100,EPB41L2,UEVLD" MicroRNA hsa-miR-1182:mirSVR_lowEffct hsa-miR-1182:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.69E-39 2.00E-35 8.51E-38 7.81E-37 100 1572 "ZFYVE27,LDLRAD3,GALNT13,FOXRED2,SNX32,SCN3A,PLA2G6,ASIC4,MOBP,CNIH2,PPFIA1,ITSN1,PKP4,DOCK10,BCAS1,PAAF1,RPH3A,SFMBT2,CGREF1,SLCO1A2,B3GAT1,NRG3,MYT1L,KIF21B,NMNAT2,B4GALNT1,ARPP21,LHFPL4,ADGRB2,BCL2L2,ALDH1L1,RHBDL3,CASTOR3,PCDH11X,CAMTA1,CAMSAP2,MMD2,PSRC1,TBX15,CACNA1E,GPR17,TCF12,HAP1,SYT6,VSTM2A,BRSK2,TF,CRB1,SPX,USP2,MFSD2A,CELF3,ZDHHC22,PAH,CDK11B,TNFRSF1B,PADI2,PDE1C,PFKFB3,GDAP1L1,UBTF,CCSER2,FAAP20,ATCAY,RNF14,PPP3CB,KCNT2,FEZ1,PRKAB2,CTNND2,MAPK10,ECE2,NOS1AP,PHYHIP,LRP8,OCIAD1,PTPRE,KCNH1,SV2A,SRGAP3,AK5,KCNJ10,KCNJ11,CCDC3,PCDH15,PYGM,KIF2A,HS3ST4,SLC17A6,FAM66C,SLC25A41,DTNA,ABCC9,CRTAC1,RFX5,FAM135B,SEC61A2,SFXN5,SLC4A10,EPB41L2" MicroRNA hsa-miR-578:mirSVR_highEffct hsa-miR-578:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.69E-39 2.00E-35 8.51E-38 7.81E-37 108 1838 "RABEPK,CNTNAP3,SYT9,ATAT1,MDM4,ADAR,DSCAML1,ADD3,WAC,NLGN4X,KIAA1109,ELMOD1,MOBP,FOXG1,ANK3,PPFIA1,ITSN1,PPM1E,MAGI3,GPAM,TACC2,SORBS1,SHTN1,PAAF1,ZNF365,RUFY2,DACH2,SMARCE1,NRG3,SON,TTLL9,IDI2-AS1,KIF1B,NASP,NCAM1,GFAP,RGL1,PCDH11X,KAZN,ADGRL3,ANO4,GPM6A,VWC2,PTBP2,CAMK2G,AKNA,GRIA2,GRIA4,GRID1,GRIK2,TGFBR3,PAX6,PADI2,LGI1,PCSK2,MAGI1,ZNF384,PDE1A,PRMT8,ZMYND8,ADGRG1,TMPRSS5,CASC2,JAM2,ZFYVE9,KIAA1549L,NRXN1,NEGR1,PMP2,PRRX1,ACBD5,CP,ETNPPL,CHD1L,CRMP1,PPP2R5C,KCNT2,VCAN,RAB39A,ARHGEF4,NRSN1,PTCH1,BDNF-AS,PRTFDC1,HP1BP3,BLOC1S6,OCIAD1,PTPRE,PLPPR4,KCNJ10,KCNK2,PCDH15,CAB39L,SLC17A6,PLEKHB2,ABI1,ATN1,DBX2,RTN4,ABCC9,ZYG11B,ZNF248,RLBP1,RPRD1A,VWA5A,EPB41L2,RCAN2,BAALC" MicroRNA hsa-miR-297:mirSVR_lowEffct hsa-miR-297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.80E-39 2.06E-35 8.72E-38 8.00E-37 101 1605 "RABEPK,EPS8,ABAT,ACER3,SYT9,EYA1,MRVI1,ARID1A,GALNT13,WAC,PNMA8B,GRAMD1B,SLC44A5,TOMM40L,ASIC4,FHL1,MOBP,TRIM46,ITSN1,PKP4,PPM1E,SORBS1,PAAF1,ARHGAP5,DACH2,CSPG5,SLIT1,ASPH,SORCS3,KBTBD12,TMEM108,ATM,SON,B3GALT2,ENKUR,ARPP21,KIF1B,NCAM1,C11orf87,AJAP1,ACSBG1,NFIA,GLS,NHLH1,KAZN,DDHD2,CAMTA1,UNC5D,WWC1,TBX15,ZEB1,PTBP2,NUDT21,GRIA1,GRIA2,GRID1,CYB561A3,OPCML,TMEM25,P2RX7,ZFP91,MAEL,CDC42,TPM3,TMEFF2,DUSP26,TJP2,PMP2,BTF3L4,FAT3,NXPH1,MFSD4A,MED1,RBPJ,PRKAB2,PLPP4,USP54,PUM1,PROX1,KIAA0408,KLK6,SPIRE1,LRRTM3,ITGAV,HP1BP3,MAGI2,KCNA4,SRGAP3,NTM,KCNK1,DLG2,RAP1GAP,GOPC,DTNA,JMJD1C,TTLL7,SYT15,RBM12,RPRD1A,ELAVL4,EPB41L2" MicroRNA hsa-miR-124-3p.1:TargetScan hsa-miR-124-3p.1 TargetScan 3.83E-39 2.07E-35 8.75E-38 8.03E-37 91 1291 "EPS8,ACHE,EYA1,CLIP1,GALNT13,RYR1,NLGN4X,DRAXIN,SCN4B,LRRC7,FGF14,ANXA7,GPAM,JAKMIP3,RUFY2,MSRA,CCDC88A,CADPS,GPR153,MTR,PALLD,KIF21B,ILDR2,RAP1GAP2,NFASC,LMO3,C11orf87,DCAF5,PHLDB1,NEUROD1,NFIA,RHBDL3,NHLH1,MYRF,MMD2,GPM6B,CACNA1E,CACNB2,GPR26,PTBP2,NUMA1,GRIA2,GRID1,RFFL,P2RX7,KCNK10,DAAM2,PADI2,PCDH8,ARHGAP19,PDE2A,PDE4B,ANO5,JAM2,GDAP1L1,CADM1,NEGR1,CNTN1,PRRX1,ATCAY,OSBPL3,PKN2,PLD5,ARHGEF4,CTNND1,MAPK10,PROX1,DPYSL5,ANKS1B,PMEPA1,PRDM2,CSDE1,BLOC1S6,KCNA1,OLFM3,PTPRD,KCNA6,PTPRZ1,KCNK2,NAV2,KCNN3,KIF2A,DNM2,RALGDS,DTNA,RFX4,FAM135B,SEC61A2,RBM12,RAVER2,EN2" MicroRNA hsa-miR-361-3p:mirSVR_lowEffct hsa-miR-361-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.63E-39 2.51E-35 1.05E-37 9.66E-37 97 1480 "MAG,SERPINA3,MAPT,SYT9,RTN3,MRVI1,RYR1,WAC,ASIC4,HPCAL4,MOBP,PKP4,DGKZ,NLGN1,LRRC55,GPR153,LGI3,B3GAT1,ATP1A3,WDTC1,B3GALT2,KIF21B,ZSWIM8,TTLL9,ADAM15,ADGRB2,ZNF302,KIRREL3,PHLDB1,SEPT3,ZNF638,ASTN2,POPDC3,DDHD2,CAMSAP2,MYRF,BTRC,WWC1,DIRAS1,NUDT21,TMEM151B,VXN,AKNA,GRID1,ADAMTS8,CRB1,FBXL16,DAAM2,PC,CDC42,PADI2,RBFOX2,ARHGAP19,PDE1A,PDE2A,PDE3B,FNDC5,ADGRG1,LRTM2,HEPACAM,NLGN3,NRXN2,PRRX1,NSD2,NXPH1,CP,CHD1L,OSBPL3,KIAA1755,PRKCG,ECE2,MASP1,PHYHIP,SIRPA,PTAFR,CNIH3,LRP8,ZC3H11A,PTPRE,KCNC1,PTPRO,SV2A,NKAIN1,OLIG1,RAB5B,DPP6,RAP1GAP,SUSD4,BSDC1,USH1C,RFX4,VANGL2,RNF220,EFNA3,YY1AP1,BSCL2,RASGRP2" MicroRNA hsa-miR-141:PITA hsa-miR-141:PITA_TOP PITA 4.85E-39 2.62E-35 1.09E-37 1.00E-36 66 626 "CSMD3,ADD3,TESK2,SEMA6A,ELMOD1,SFPQ,ITSN1,PPM1E,DOCK10,CCDC80,ST3GAL3,MIER1,SLC6A9,ASTN1,RCOR3,IGSF9B,PHYHIPL,MYT1L,SOX5,ZCCHC24,KIF1B,NFASC,NCAM1,LMO3,CLASP2,GLS,SYT4,CAMSAP2,TCF12,AZIN2,SYT6,ADAMTS8,TJP1,ZFP91,TNS1,PCDH8,PCDH9,CDH10,ACOT7,HMGB1,CADM1,NRXN1,CCSER2,NSD2,FAT3,POU3F2,MED1,ATRNL1,NCAN,CTNND2,KIAA0408,LRRTM3,PTCH1,CEP170,PTPRD,SMG7,SNX27,DLG3,SLC17A6,ZYG11B,ATL1,ZNF248,TTLL7,RBM12,RAVER2,ELAVL4" MicroRNA hsa-miR-200a:PITA hsa-miR-200a:PITA_TOP PITA 4.85E-39 2.62E-35 1.09E-37 1.00E-36 66 626 "CSMD3,ADD3,TESK2,SEMA6A,ELMOD1,SFPQ,ITSN1,PPM1E,DOCK10,CCDC80,ST3GAL3,MIER1,SLC6A9,ASTN1,RCOR3,IGSF9B,PHYHIPL,MYT1L,SOX5,ZCCHC24,KIF1B,NFASC,NCAM1,LMO3,CLASP2,GLS,SYT4,CAMSAP2,TCF12,AZIN2,SYT6,ADAMTS8,TJP1,ZFP91,TNS1,PCDH8,PCDH9,CDH10,ACOT7,HMGB1,CADM1,NRXN1,CCSER2,NSD2,FAT3,POU3F2,MED1,ATRNL1,NCAN,CTNND2,KIAA0408,LRRTM3,PTCH1,CEP170,PTPRD,SMG7,SNX27,DLG3,SLC17A6,ZYG11B,ATL1,ZNF248,TTLL7,RBM12,RAVER2,ELAVL4" MicroRNA hsa-miR-644:mirSVR_lowEffct hsa-miR-644:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-39 2.80E-35 1.16E-37 1.07E-36 95 1419 "LOC100128239,ZFYVE27,ACER3,MAP6,CDHR1,SYT9,ATAT1,ADORA3,FOXRED2,SNX32,ASIC4,FHL1,PPFIA1,DGKZ,SYBU,ZNF365,SLC1A7,BCO1,MSR1,SLC8A2,MT3,CCDC88A,CADPS,CGREF1,ARFGAP1,SLN,ALDH4A1,ATP1A2,WDTC1,CADM3,CAB39,ADAM15,FXYD6,NPAS3,LMO3,ALDH1L1,GFAP,NHLH1,KAZN,ANO4,GPR17,PCDHGA3,VXN,GRIA4,GRIK2,OPCML,GUCY1A1,CELF3,PADI2,PCDH9,ZNF384,PDE1A,PRMT8,LRTM2,KIAA1549L,NEGR1,OPALIN,TJP2,ST8SIA5,SULT4A1,PRRX1,NSD2,ATCAY,SNCAIP,CHD5,RBPJ,PRKAB2,RAB39A,NRSN1,MASP1,PRDM2,COPS7A,RGMA,PLPPR4,AK5,TMCC2,KCNJ11,ARNT2,KCNK1,KCNK2,PCDH15,NKAIN1,DNM2,SLC17A6,GNE,DBX2,ABCC9,CAMK1G,USH1C,ARHGEF10L,RPRD1A,ELAVL4,EN2,UEVLD,BAALC" MicroRNA hsa-miR-195:mirSVR_highEffct hsa-miR-195:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.48E-39 2.97E-35 1.23E-37 1.13E-36 95 1420 "MAP6,CDHR1,RTN3,SYNDIG1,EYA1,CSMD2,GALNT13,CDC7,SCN3A,DISP3,LRRC7,ELMOD1,SLC30A10,SGIP1,ANK2,SH3GL2,PPM1E,NLGN1,ST3GAL3,BCAS1,API5,ARFGAP2,CSPG5,SLN,RCOR3,SNAP25,PHYHIPL,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,NAP1L2,NPAS3,NFASC,LMO3,BCL2L2,RGL1,ACSBG1,SYT4,KAZN,BTRC,WWC1,PTBP2,CAMK2G,VSTM2A,OMG,PTPN5,TGFBR3,TMEM9,CDC42,PCDH9,PDE3B,BEST3,CADM1,PLXNB3,BTF3L4,PRRX1,NXPH1,ACBD5,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,MICAL2,RBPJ,PKN2,MASP1,PTCH1,JAKMIP2,PMEPA1,PTHLH,CSDE1,PTPRD,SMG7,KCNJ11,KCNK1,KCNK2,PEX5,DLG2,KIF2A,DNAH9,PID1,TMEM255A,RET,RFX4,SEC61A2,SIDT2,RBM12,ABI2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-541:mirSVR_lowEffct hsa-miR-541:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.09E-39 3.30E-35 1.36E-37 1.24E-36 104 1713 "RABEPK,CDHR1,WLS,ADARB2,TUBB4A,CHST15,MOBP,TRIM46,ANK1,ITSN1,MAGI3,DGKZ,DGKD,ZNF365,RPH3A,MADD,SLC8A3,MT3,ASPH,B3GAT1,TMEM108,SNAP25,ATP1A2,KIF21B,CADM3,SOX10,ZSWIM8,B4GALNT1,IDI2-AS1,FXYD6,NFASC,KIRREL3,PCDH11X,C1QC,OS9,GNAS,GNG3,MYRF,ADGRL3,TMEM136,CACNA1A,PRUNE2,GPM6B,DDR1,CACNB2,NRGN,HAP1,AZIN2,TMEM151B,GRIA1,GRIA4,GRID1,RFFL,GRIN1,GPR88,CYB561A3,SHISA7,USP2,HPS5,PADI2,HRH3,PDE4B,HAPLN2,BEST3,CHGA,ASIC3,CASC2,DLGAP3,PLXNB3,C11orf49,MEAF6,CELF5,PRRX1,NECAB2,FAT3,CP,PNKD,SNCAIP,NKAIN4,FEZ1,MICAL2,RBPJ,KIAA1755,RAB39A,MASP1,WBP1L,PHYHIP,CEP170,KCNA6,NTM,TMCC2,KCNJ11,KCNK1,KCNMA1,WIPF2,DNM2,RAP1GAP,ABI1,RASGRF1,DBX2,CAMK1G,RFX4,LMO1,EN2" MicroRNA hsa-miR-101*:mirSVR_lowEffct hsa-miR-101*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.40E-39 3.47E-35 1.42E-37 1.30E-36 104 1714 "LGR4,RCSD1,ARID1A,WLS,CSMD3,RTN1,ADD3,NLGN4X,SLC44A5,FCGR1B,LINC00461,KIAA1109,SLC30A10,FOXG1,SOX6,RASA3,ITSN1,DOCK10,NTNG1,MAGI3,CCDC80,ZCCHC17,NLGN1,SHTN1,DACH2,RCOR3,SNAP25,ATM,PHYHIPL,SON,B3GALT2,TNIK,NMNAT2,NPAS3,NDUFA5,SMOC1,ADHFE1,NEUROD1,AJAP1,SLCO1C1,PCDH11X,POPDC3,LUZP2,ADGRL3,KLHL4,TCF7L2,GRIA4,RFFL,GRIK2,USP2,MFSD2A,TLL2,CDK11B,REPS2,PADI2,PCDH8,PCDH9,DCLK1,TPD52,TPM3,LINC01102,ZFYVE9,TJP2,CNTN1,CABP1,CELF5,NSD2,CHD1L,SNCAIP,TENM4,KCNT2,OSBPL3,VCAN,PHACTR3,DZIP3,PLD5,NRSN1,EDRF1,NOS1AP,FGFR1OP2,TOX,DNAJC6,BDNF-AS,CADM2,PRTFDC1,PTPRD,KCNA6,PTPRE,PTPRZ1,KCNK2,WIPF2,SLC17A6,FAM13C,DBX2,ABCC9,ZYG11B,RGS10,TTLL7,SEC61A2,SSPN,ABI2,ARHGAP12,SLC4A10,TMEM100" MicroRNA hsa-miR-376a*:mirSVR_lowEffct hsa-miR-376a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.03E-39 4.35E-35 1.77E-37 1.63E-36 105 1752 "SDE2,LGR4,ADGRV1,CSMD2,GRAMD1B,TMEM156,TESK2,LRRC7,ELMOD1,SOX6,ANK1,ANK3,PPM1E,APBB1,LRRC4C,API5,CCDC88A,SLC14A1,DACH2,ASCL1,SLCO1A2,ATP1A2,ZCCHC24,GAD2,ENKUR,NKX6-2,KIF1B,NPAS3,NCAM1,LMO3,C11orf87,BCL2L2,ALDH1L1,ERBIN,SEPT3,PCDH11X,KAZN,UNC5D,BTRC,WWC1,CACNA1A,CAMK2A,CAMK2G,GRIA4,OLR1,OMG,CRB1,TJP1,ATG4C,REPS2,PC,TNS1,PCDH9,RBFOX2,PDE2A,PDE3B,PRMT8,BEST3,SCRG1,ANO5,PFKFB3,HEPACAM,CADM1,ANLN,P2RY12,CNRIP1,PPP2R5C,FEZ2,MICAL2,VCAN,PRKACB,PKN2,PUM1,FAM131B,MASP1,ZBTB16,LRRTM3,PTAFR,DNAJC6,JAKMIP2,CADM2,PRTFDC1,COPS7A,CSDE1,MAGI2,KCNA4,SMG7,KCNJ9,RABGAP1L,PCDH15,NAV2,PID1,KLRC3,PARP11,FAM13C,PAK5,ABCC9,SLC6A15,RET,USH1C,JMJD1C,ZNF248,TTLL7,SEC61A2,RBM12" MicroRNA hsa-miR-497:mirSVR_highEffct hsa-miR-497:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.31E-39 4.50E-35 1.83E-37 1.68E-36 93 1365 "ZFYVE27,CDHR1,RTN3,SYNDIG1,EYA1,ATAT1,CSMD2,SLITRK1,GALNT13,SCN3A,LINC00461,DISP3,LRRC7,ELMOD1,SLC30A10,ANK2,SH3GL2,PPM1E,NLGN1,ST3GAL3,BCAS1,CCDC88A,CSPG5,SLN,RCOR3,SNAP25,PHYHIPL,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,NAP1L2,NPAS3,NFASC,BCL2L2,PHLDB1,ACSBG1,SYT4,KAZN,GNAS,UNC5D,BTRC,WWC1,VSTM2A,GRIA2,OMG,TGFBR3,CDC42,PCDH9,PDE3B,BEST3,CADM1,BTF3L4,PRRX1,NXPH1,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,MICAL2,RBPJ,MASP1,TOX,SYTL2,ANKS1B,JAKMIP2,PTHLH,CSDE1,PTPRD,KCNJ11,KCNK1,KCNK2,PEX5,DLG2,NKAIN1,KIF2A,DNAH9,PID1,TMEM255A,RET,RFX4,RFX5,SEC61A2,SIDT2,RBM12,ABI2,ARHGAP12,EN2,TMEM100,RCAN2" MicroRNA hsa-miR-130b:mirSVR_lowEffct hsa-miR-130b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.44E-39 4.57E-35 1.84E-37 1.69E-36 105 1753 "PRR5L,ASIC1,LGR4,LDLRAD3,CSMD2,WAC,FCGR1A,CHST15,SCN4B,LRRC7,BCAR3,MOBP,FOXG1,SELL,ITSN1,DOCK10,APC,SLITRK3,SHTN1,ARHGAP5,ASCL1,RCOR3,ATP1A2,SCN3B,B3GALT2,KIF21B,CAB39,EMC1,DNER,NAP1L2,LMO3,ALDH1L1,NDUFA5,AJAP1,MLC1,VAMP1,SYT4,KAZN,BTRC,TMEM136,ATF7,ZEB1,AZIN2,CAMK2G,CECR2,TMEM151B,VSTM2A,OPCML,TGFBR3,USP2,GUCY1A1,CELF3,ZFP91,KCNK10,REPS2,HPS5,CDC42,DCLK1,RBFOX2,TPD52,MAGI1,PDE1A,PDE4B,PIRT,SCRG1,PFKFB3,MS4A7,SEMA5B,VAV2,SLC25A27,P2RY12,NSD2,FAT3,FEZ2,MICAL2,DZIP3,FMN2,SPIRE1,ZNF385B,LRRTM3,ELMO1,MAGI2,KCNA4,PTPRD,PTPRZ1,NTM,KCNJ10,KCNK1,SNX27,DLG2,DLG3,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,FAM13C,DTNA,BSDC1,RFX5,PIANP,SLC4A10,C2orf80,TMEM100,UEVLD" MicroRNA hsa-miR-146b-5p:mirSVR_lowEffct hsa-miR-146b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.44E-39 4.57E-35 1.84E-37 1.69E-36 108 1855 "RABEPK,EPS8,ZFYVE27,ACER3,MAP6,CDHR1,DUSP27,RCSD1,ADGRV1,MRVI1,CSMD2,ARID1A,ADCY2,CHST15,GPR158,SNX32,LRRTM4,ANK2,ANXA7,MAGI3,SORBS1,SHTN1,CLSTN1,ZNF365,BCO1,RUFY2,DNAH17,ASPH,RCOR3,IGSF9B,ATM,NRG3,SCN3B,SOX10,GAD2,ZSWIM8,ADAM15,GART,NPAS3,SPART,SMOC1,GLS,NHLH1,DCLK2,NODAL,UNC5D,MMD2,TMEM136,GPM6A,GPM6B,B4GALNT4,GPR19,GRIA1,VWCE,TMEM257,DAAM2,REPS2,PADI2,PCDH9,CDH8,DCLK1,SEZ6L,TPD52,PCSK2,FNDC5,GPR37L1,ANO5,CHRNB2,SERPINE2,CADM1,ANLN,OPALIN,CNTN1,MEAF6,CELF5,PRRX1,SLC36A4,NXPH1,CHD1L,SF1,RNF14,PPP2R5C,PPP3CB,OSBPL3,ATRNL1,PRKACB,ARHGEF4,ECE2,SYNC,PTAFR,PTCH1,CNIH3,PRDM2,LRP8,KCNA6,PTPRZ1,NAV2,DLG2,TMEM255A,RALGDS,C12orf4,DSCAM,FAM135B,ZNF248,SEC61A2,FGFBP3,C2orf80,SEZ6" MicroRNA hsa-miR-1262:mirSVR_lowEffct hsa-miR-1262:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.56E-39 4.63E-35 1.86E-37 1.71E-36 98 1523 "RABEPK,ABAT,SYNDIG1,CEND1,EYA1,LDLRAD3,CSMD2,MDM4,CSMD3,ADCY2,DSCAML1,SLC44A5,GPR158,SNX32,HOGA1,LRRTM4,ASIC4,MOBP,TRIM46,ANK3,ITSN1,SFMBT2,SLCO1A2,DLL3,SORCS3,B3GAT1,TMEM151A,MEGF11,MYT1L,KIF21B,B4GALNT1,EMC1,LMO3,ZNF302,DCAF5,ADHFE1,KAZN,GPM6B,ZEB1,NRGN,AZIN2,VSTM2A,GRIA1,GRIK2,USP2,TNFRSF1B,HPS5,MAGI1,PDE3B,LINC01102,ZMYND8,ASIC3,CASC2,HNRNPK,DUSP26,GDAP1L1,CAMKV,ST8SIA5,SULT4A1,CCDC136,PRRX1,FAT3,CHD1L,CRLS1,SNCAIP,PPP3CB,OSBPL3,ATRNL1,PRKACB,KIAA1755,PRKCG,USP54,MASP1,TOX,GON4L,PLPPR5,SYNC,PTCH1,PTHLH,PRDM2,MAGI2,PTPRD,PTPRE,KCNC1,PTPRZ1,KCNK1,PCDH15,NKAIN1,RAB3IL1,FAM66C,PARP11,BSDC1,NUP214,USH1C,RFX5,RGR,ABI2,TMEM100" MicroRNA hsa-miR-330-3p:PITA hsa-miR-330-3p:PITA_TOP PITA 9.09E-39 4.92E-35 1.97E-37 1.81E-36 69 703 "KCNIP2,KLHL32,ADD3,SORCS1,SCN3A,HPCAL4,FOXG1,AMPH,SH3GL2,PPM1E,APC,GPAM,API5,AQP4,CADPS,RCOR3,IGSF9B,ATP2B2,ZCCHC24,CADM3,ERBIN,UNC5D,BTRC,GPM6A,PTBP2,CAMK2G,PSD3,GRID1,TGFBR3,GUCY1A2,TJP1,CELF3,TNS1,PCDH9,DCLK1,TPM3,PDE3B,HNRNPK,JAM2,PRRX1,NSD2,ACBD5,PPP2R5C,OSBPL3,PRKAB2,MAPK10,KIAA0408,TOX,CADM2,ELMO1,LRP8,KCNA1,OCIAD1,PTPRD,SMG7,PTPRO,DLG2,NKAIN1,KIF2A,SLC17A6,ST8SIA3,PHC2,EFNA3,RBM12,ARHGAP12,RAVER2,SLC4A10,EPB41L1,EPB41L2" MicroRNA hsa-miR-374b:PITA hsa-miR-374b:PITA_TOP PITA 1.02E-38 5.54E-35 2.20E-37 2.02E-36 72 778 "ABAT,ACLY,EYA1,MRVI1,CSMD2,MDM4,SLITRK1,ADD3,GRAMD1B,KIAA1109,SLC30A10,FOXG1,APC,GAS7,NLGN1,ARHGAP5,ASCL1,TMEM108,ATP2B2,MYT1L,ZCCHC24,NEUROD1,ARHGEF7,NKX2-2,CAMSAP2,ANO4,GPM6A,ACSL6,VWC2,CACNB2,TCF12,PSD3,TJP1,REPS2,TNS1,RBFOX2,SEZ6L,ZNF384,PDE4B,TMEFF2,JAM2,NEGR1,ANLN,SLC25A27,SF1,PHACTR3,RBPJ,PRKAB2,FMN2,FAM131B,BRINP3,TOX,DNAJC6,PMEPA1,CADM2,KCNA1,DLG2,DLG3,RAB5B,RALGDS,GOPC,PAK5,BSDC1,JMJD1C,FAM135B,INSYN2,ARHGEF10L,TTLL7,SLC4A10,EN2,EPB41L2,SEZ6" MicroRNA hsa-miR-374a:PITA hsa-miR-374a:PITA_TOP PITA 1.02E-38 5.54E-35 2.20E-37 2.02E-36 72 778 "ABAT,ACLY,EYA1,MRVI1,CSMD2,MDM4,SLITRK1,ADD3,GRAMD1B,KIAA1109,SLC30A10,FOXG1,APC,GAS7,NLGN1,ARHGAP5,ASCL1,TMEM108,ATP2B2,MYT1L,ZCCHC24,NEUROD1,ARHGEF7,NKX2-2,CAMSAP2,ANO4,GPM6A,ACSL6,VWC2,CACNB2,TCF12,PSD3,TJP1,REPS2,TNS1,RBFOX2,SEZ6L,ZNF384,PDE4B,TMEFF2,JAM2,NEGR1,ANLN,SLC25A27,SF1,PHACTR3,RBPJ,PRKAB2,FMN2,FAM131B,BRINP3,TOX,DNAJC6,PMEPA1,CADM2,KCNA1,DLG2,DLG3,RAB5B,RALGDS,GOPC,PAK5,BSDC1,JMJD1C,FAM135B,INSYN2,ARHGEF10L,TTLL7,SLC4A10,EN2,EPB41L2,SEZ6" MicroRNA hsa-miR-448:mirSVR_highEffct hsa-miR-448:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.04E-38 5.62E-35 2.22E-37 2.04E-36 101 1624 "WLS,KLHL32,ADD3,SORCS1,AMER2,CHST15,KIAA1109,MOBP,ANK3,USP28,PPFIA1,ITSN1,SH3GL2,GPAM,NLGN1,API5,MIER1,SFMBT2,RUFY2,ASPH,ATM,NRG3,PHYHIPL,ATP2B2,PALLD,SOX1,ZCCHC24,ENKUR,ARPP21,EMC1,NEK6,NPAS3,LMO3,C11orf87,ZNF302,DCAF5,RGL1,AJAP1,SYT4,ANO4,GPM6A,PTBP2,GRIK2,CRB1,INA,GUCY1A1,TJP1,PAX6,CDC42,PCDH8,PCDH9,CDH10,LGI1,LINC01102,SCRG1,ANO5,CASC2,SERPINE2,ANLN,SULT4A1,CELF5,SPATA6,RNF14,CRLS1,PPP2R5C,FEZ2,OSBPL3,ATRNL1,PRKAB2,DZIP3,PKN2,PLD5,CTNND1,CTNND2,TOX,GON4L,SPIRE1,DNAJC6,BDNF-AS,CADM2,COPS7A,CSDE1,BLOC1S6,KCNA4,PTPRD,PTPRE,PCDH15,RAB5B,C12orf4,ABI1,FAM13C,DTNA,ABCC9,SLC6A15,RFX4,JMJD1C,ZNF248,TTLL7,SSPN,SLC4A10,UEVLD" MicroRNA hsa-miR-1914*:mirSVR_lowEffct hsa-miR-1914*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-38 5.78E-35 2.28E-37 2.09E-36 97 1495 "DPF1,TTYH1,ZFYVE27,ACER3,ASIC1,MAPT,MBP,MEG3,ECSIT,ADAR,CLIP1,GALNT13,ERMN,TUBB4A,CHST15,SNX32,PLA2G6,GOLGA7B,ANK1,CNIH2,ITSN1,GPAM,BCAN,CACHD1,AQP4,PKNOX2,YPEL4,MT3,CGREF1,SLIT1,ATP1A3,PHYHIPL,SON,WDTC1,TNIK,ZCCHC24,NFASC,C11orf87,COLGALT2,BCL2L2,NCDN,CAMTA1,CDK5R2,UNC5D,GOLGB1,WWC1,VWC2,ZEB1,NRGN,NUDT21,EML4,BRSK2,GRIA1,ADAMTS8,USP2,FBXL16,PTGDR2,HRH3,SEZ6L,TPM4,NTSR2,HMGB1,TMPRSS5,PLEKHB1,TLX1,GDAP1L1,NOMO2,FADS2,FTO,FAM181B,CNTN1,BEST1,COL9A2,PRRX1,NECAB2,CHD1L,DZIP3,ARHGEF4,CTNND2,MASP1,ANKS1B,PTAFR,RGMA,TMCC2,KCNK2,PCDH15,DNAH9,PARP11,RALGDS,SLC25A18,RASGRF1,CAMK1G,VANGL2,RPRD1A,LMO1,ABI2,EPB41L2" MicroRNA hsa-miR-378b:mirSVR_lowEffct hsa-miR-378b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-38 7.17E-35 2.81E-37 2.58E-36 98 1531 "SERPINA3,SYT9,SYNDIG1,MRVI1,ADAR,ADCY2,ADD3,ADORA1,SNX32,FGR,SOX6,CDC42BPA,APBA2,NTNG1,MAGI3,CCDC80,ZCCHC17,PAAF1,MSR1,MSRA,LRRC55,PKNOX2,SLC8A2,SLC8A3,SPHKAP,CAPRIN2,ASPH,KBTBD12,B3GAT1,NRG3,DKK3,WDTC1,ZCCHC24,CAB39,NMNAT2,NFASC,SMOC1,GPR162,NELL1,ADHFE1,ZNF638,DCLK2,MMD2,ANO4,TBX15,GPM6B,TCF7L2,CLEC9A,TCF12,PTBP2,CAMK2A,VXN,SYT6,NUMA1,AKNA,GRIK2,GPR88,FBXL16,TNFRSF1B,PCDH9,DCLK1,TPM4,LINC01102,GPR37L1,ANO5,CASC2,NLGN3,NMT2,CCSER2,FTO,CELF5,MFSD4A,CHD1L,SF1,CRLS1,SNCAIP,KCNT2,ATRNL1,NCAN,EDRF1,SIRPA,DNAJC6,PRDM2,KCNJ10,KCNN3,PEX5,DLG2,OLIG1,RASGRF1,L1CAM,NUP214,FAM135B,VANGL2,RNF220,SSPN,SLC4A10,EN2,SEZ6" MicroRNA hsa-miR-502-5p:mirSVR_lowEffct hsa-miR-502-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-38 9.20E-35 3.60E-37 3.30E-36 106 1801 "EPS8,ABAT,LOC100128239,ZFYVE27,CDHR1,MBP,MEG3,ADGRV1,ATAT1,CSMD2,WLS,NLGN4X,GPR158,TESK2,FGF1,GOLGA7B,TRIM46,ITSN1,SESN3,DGKZ,JAKMIP3,AQP4,MIER1,SLC1A7,ARFGAP2,SLC14A1,DLL3,MTR,KBTBD12,EIF4G3,MEGF11,USP33,SOX1,MYT1L,CADM3,ZSWIM8,ARPP21,IDI2-AS1,DNER,FXYD6,SPART,C11orf87,ALDH1L1,ADHFE1,OS9,SYT4,KAZN,GNAS,NODAL,UNC5D,CNTN2,GOLGB1,WSCD1,CACNB2,VXN,VSTM2A,GRIA1,GRIA2,GRIK2,LINC00839,TGFBR3,P2RX7,TIE1,TMEM9,TMEM257,ZDHHC22,MAEL,SEZ6L,TPD52,TPM3,PCSK2,PDE1A,PRMT8,ZMYND8,CHRNB2,NRXN1,PLXNB3,PRRX1,PACSIN1,ATCAY,PNKD,RGS6,RBPJ,PRKAB2,CTNND1,NOS1AP,TOMM20,SYNC,BDNF-AS,PRDM2,KCNA1,KCNA6,C1orf109,PTPRZ1,NKAIN1,OLIG1,WIPF2,DNM2,SLC25A41,ZNF248,VANGL2,RLBP1,GPR61,ABI2,EPB41,EPB41L1" MicroRNA hsa-miR-328:mirSVR_lowEffct hsa-miR-328:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-38 9.43E-35 3.67E-37 3.37E-36 91 1316 "EPS8,ZFYVE27,MBP,PAQR6,MEG3,CSMD2,SLC25A25,GALNT13,SORCS1,GRAMD1B,SNX30,TOMM40L,HOGA1,FHL1,MOBP,TRIM46,APBA2,DGKZ,ZCCHC17,ZNF365,RUFY2,LRRC55,CCDC88A,SCG3,NAXD,RCOR3,WDTC1,B3GALT2,ZSWIM8,NFASC,C11orf87,ALDH1L1,GJB1,PHLDB1,SEPT3,ARHGEF7,GLS,OS9,GNAS,GNG3,ANO4,ZEB1,HAP1,SYT6,VSTM2A,NUMA1,GRIA1,GRIA2,TF,LINC00839,LEFTY2,DAAM2,MAGI1,PDE1A,PRMT8,HMGB1,ANO5,CHGA,GDAP1L1,KIAA1549L,NEGR1,CPT1C,OPALIN,CCDC136,PLXNB3,CABP1,BEST1,PNKD,SNCAIP,ATRNL1,CTNND2,PHYHIP,SPIRE1,LRRTM3,DNAJC6,ITGAV,PLPPR1,PTPRO,KCND3,KCNJ9,CCDC3,KCNMA1,HS3ST4,SLC25A48,FAM66C,NUP214,USH1C,ARHGEF10L,RNF220,GPR61,BAALC" MicroRNA hsa-miR-16:mirSVR_highEffct hsa-miR-16:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.81E-38 9.82E-35 3.81E-37 3.49E-36 95 1441 "CDHR1,RTN3,SYNDIG1,EYA1,CSMD2,GALNT13,CDC7,SCN3A,DISP3,LRRC7,ELMOD1,SLC30A10,ANK2,SH3GL2,PPM1E,NLGN1,ST3GAL3,BCAS1,API5,CSPG5,SLN,RCOR3,SNAP25,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,NAP1L2,NPAS3,NFASC,BCL2L2,RGL1,ACSBG1,GLS,SYT4,KAZN,BTRC,WWC1,CACNA1E,PTBP2,VSTM2A,OMG,CRB1,TGFBR3,CDC42,C1orf94,PCDH9,PDE3B,BEST3,CADM1,PLXNB3,PRRX1,NXPH1,ACBD5,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,MICAL2,VCAN,RBPJ,PKN2,ARHGEF4,MASP1,PTCH1,JAKMIP2,PMEPA1,PTHLH,LRP8,CSDE1,PTPRD,SMG7,KCNJ11,KCNK1,KCNK2,PEX5,DLG2,KIF2A,DNAH9,PID1,TMEM255A,ZYG11B,RET,RFX4,RFX5,SEC61A2,SIDT2,RBM12,ABI2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-19b-3p:TargetScan hsa-miR-19b-3p TargetScan 1.99E-38 1.08E-34 4.14E-37 3.80E-36 79 970 "PRR5L,RIMKLA,EYA1,ARID1A,MDM4,F3,CLIP1,RTN1,ADD3,GRAMD1B,SCN3A,SCN4B,ASIC4,CDC42BPA,ITSN1,ANXA7,DOCK10,MIER1,ARHGAP5,CCDC88A,GPR153,CAPRIN2,RCOR3,ATP1A2,ATP2B2,DKK3,MYT1L,CAB39,KIF1B,NPAS3,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,KAZN,CAMSAP2,PRUNE2,CECR2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CHRNB2,NMT2,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CRMP1,MICAL2,CHD5,PRKACB,MAPK8,PROX1,PSD,DPYSL5,PMEPA1,CADM2,CEP170,MAGI2,KCNA4,CDH20,PTPRD,KCNH1,KCNK2,CAB39L,RAB5B,ATG16L1,DSCAM,DTNA,RFX4,SEC61A2,PIANP,ABI2,ARHGAP12,CBLN2" MicroRNA hsa-miR-19a-3p:TargetScan hsa-miR-19a-3p TargetScan 1.99E-38 1.08E-34 4.14E-37 3.80E-36 79 970 "PRR5L,RIMKLA,EYA1,ARID1A,MDM4,F3,CLIP1,RTN1,ADD3,GRAMD1B,SCN3A,SCN4B,ASIC4,CDC42BPA,ITSN1,ANXA7,DOCK10,MIER1,ARHGAP5,CCDC88A,GPR153,CAPRIN2,RCOR3,ATP1A2,ATP2B2,DKK3,MYT1L,CAB39,KIF1B,NPAS3,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,KAZN,CAMSAP2,PRUNE2,CECR2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CHRNB2,NMT2,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CRMP1,MICAL2,CHD5,PRKACB,MAPK8,PROX1,PSD,DPYSL5,PMEPA1,CADM2,CEP170,MAGI2,KCNA4,CDH20,PTPRD,KCNH1,KCNK2,CAB39L,RAB5B,ATG16L1,DSCAM,DTNA,RFX4,SEC61A2,PIANP,ABI2,ARHGAP12,CBLN2" MicroRNA hsa-miR-3137:mirSVR_lowEffct hsa-miR-3137:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-38 1.13E-34 4.33E-37 3.97E-36 94 1412 "ACER3,EXTL1,MDM4,F3,FABP7,SORCS1,ADORA3,FOXRED2,GPR158,SCN3A,LRRTM4,KIAA1109,UNC79,ANK3,PPFIA1,ITSN1,NTNG1,DGKD,SORBS1,CACHD1,ST3GAL3,API5,AQP4,RUFY2,MSRA,LRRC55,PDE8B,SLIT1,TMEM108,PHYHIPL,MEGF11,SON,WDTC1,SOX5,ZSWIM8,EMC1,C11orf87,NDUFA5,DCAF5,PCDH11X,POPDC3,BTRC,GPR17,PTBP2,NUDT21,CAMK2G,TMEM151B,OPCML,P2RX7,TMEM257,MAEL,SEZ6L,TPM3,PDE1A,HPSE2,ASIC3,CHRM1,NEGR1,NMT2,FADS2,C11orf49,COL9A2,PRRX1,SPATA6,IFFO1,FAT3,MFSD4A,RNF14,SNCAIP,KCNT2,FEZ1,PKN2,MAPK10,ZNF385B,PSMD13,CA10,PRDM2,PRTFDC1,COPS7A,MAGI2,PTPRZ1,KCNH1,SRGAP3,RABGAP1L,KCNK1,WIPF2,PLEKHB2,FAM66C,PAK5,ABCC9,SLC6A15,RFX4,TTLL7,BAALC" MicroRNA hsa-miR-376b:mirSVR_lowEffct hsa-miR-376b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-38 1.17E-34 4.46E-37 4.09E-36 101 1638 "MBP,CNTNAP3,RTN3,MEG3,ATAT1,GALNT13,ERMN,TUBB4A,NLGN4X,AGT,FGF1,PLA2G6,FGF14,FOXG1,SFPQ,ANK3,PPFIA1,ANXA7,PKP4,PPM1E,DGKD,NLGN1,MSR1,MSRA,ARHGAP5,SLC8A3,DACH2,MTR,ASTN1,TMEM108,ATM,PALLD,SON,WDTC1,ENKUR,C11orf87,CLASP2,STOX1,ADHFE1,NEUROD1,SEPT3,GLS,LUZP2,GNAS,UNC5D,WWC1,TMEM136,ATF7,CACNA1E,CACNB2,PTBP2,GRIA2,GRIK3,GRM3,TGFBR3,TLL2,CELF3,ZFP91,PAH,MAEL,PAX6,C1orf94,PCDH8,DCLK1,PDYN,PFKFB3,TUB,ZFYVE9,NEGR1,A2ML1,OPALIN,ST8SIA5,SLC36A4,FAT3,PTPA,MICAL2,RBPJ,DZIP3,FMN2,CMTM5,PLD5,PUM1,HES5,FAM131B,JAKMIP2,CADM2,LRP8,CEP170,MAGI2,BLOC1S6,SRGAP3,ARNT2,KCNK2,PEX5,DLG2,TMEM255A,GNE,FAM13C,ABI2,SLC4A10,EN2" MicroRNA hsa-miR-4260:mirSVR_lowEffct hsa-miR-4260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-38 1.30E-34 4.92E-37 4.51E-36 95 1446 "PRR5L,ZFYVE27,ACER3,ASIC1,CSMD2,ARID1A,KCNIP2,CSMD3,DSCAML1,SLITRK1,GALNT13,GRAMD1B,ASIC4,FGR,MOG,AMPH,ITSN1,MAGI3,DGKZ,GPAM,BCAS1,MADD,PKNOX2,SLC8A2,CGREF1,PDE8B,NAXD,SLN,NRG3,DKK3,WDTC1,ZCCHC24,GAD2,ZSWIM8,TTLL9,ADAM15,KIF1B,NCAM1,COLGALT2,SMOC1,DCAF5,SLCO1C1,MLC1,GLS,VAMP1,GNAS,UNC5D,TCF12,NRGN,CECR2,TMEM151B,GRID1,ATP13A2,CRB1,SPX,LEFTY2,NEURL1,ZFP91,DAAM2,LINC01102,PFKFB3,ASIC3,HEPACAM,NMT2,C11orf49,CRLS1,TENM4,PPP3CB,MICAL2,PRKCG,PKN2,IGSF1,CTNND2,ECE2,PHYHIP,DNAJC6,CNIH3,PRDM2,SV2A,SRGAP3,TMCC2,PCDH15,KCNMA1,DLG2,KLRC2,DNM2,RAD52,SLC25A41,RAP1GAP,DBX2,SLC6A15,ST8SIA3,SFXN5,ARHGAP12,SEZ6" MicroRNA hsa-miR-27b-3p:TargetScan hsa-miR-27b-3p TargetScan 2.41E-38 1.30E-34 4.92E-37 4.51E-36 81 1028 "EPS8,ABAT,ASIC1,MAPT,ACLY,LGR4,EYA1,MDM4,F3,ADD3,KIAA1109,FGF1,FGF14,ANK1,ANK2,ANK3,PPM1E,APBA2,APC,MAGI3,GPAM,PKNOX2,PDE8B,CAPRIN2,RCOR3,ALDH4A1,ATP1A2,SCN3B,KIF21B,CAB39,NEK6,NPAS3,NFASC,NCAM1,C11orf87,COLGALT2,FAM168A,ACSBG1,NFIA,KLHL4,CACNA1A,CACNB2,B4GALNT4,DIRAS1,CAMK2A,CECR2,BRSK2,GRIK3,MFSD2A,PAX6,REPS2,PCDH9,PDE3B,PRMT8,DLGAP3,CADM1,NRXN1,CABP1,POU3F2,RIMS4,MAPK10,KIAA0513,RIMS3,CA10,ELMO1,MAGI2,KCNA4,KCNA6,KCNK2,NAV2,KCNN3,NKAIN1,RASGRF1,DTNA,RET,JMJD1C,LPAR6,EN2,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-27a-3p:TargetScan hsa-miR-27a-3p TargetScan 2.41E-38 1.30E-34 4.92E-37 4.51E-36 81 1028 "EPS8,ABAT,ASIC1,MAPT,ACLY,LGR4,EYA1,MDM4,F3,ADD3,KIAA1109,FGF1,FGF14,ANK1,ANK2,ANK3,PPM1E,APBA2,APC,MAGI3,GPAM,PKNOX2,PDE8B,CAPRIN2,RCOR3,ALDH4A1,ATP1A2,SCN3B,KIF21B,CAB39,NEK6,NPAS3,NFASC,NCAM1,C11orf87,COLGALT2,FAM168A,ACSBG1,NFIA,KLHL4,CACNA1A,CACNB2,B4GALNT4,DIRAS1,CAMK2A,CECR2,BRSK2,GRIK3,MFSD2A,PAX6,REPS2,PCDH9,PDE3B,PRMT8,DLGAP3,CADM1,NRXN1,CABP1,POU3F2,RIMS4,MAPK10,KIAA0513,RIMS3,CA10,ELMO1,MAGI2,KCNA4,KCNA6,KCNK2,NAV2,KCNN3,NKAIN1,RASGRF1,DTNA,RET,JMJD1C,LPAR6,EN2,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-130a:mirSVR_lowEffct hsa-miR-130a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.90E-38 1.57E-34 5.90E-37 5.42E-36 104 1744 "RABEPK,PRR5L,ACER3,ASIC1,LGR4,LDLRAD3,CSMD2,WAC,ERMN,FCGR1A,CHST15,SCN4B,LRRC7,BCAR3,FOXG1,SELL,ITSN1,SHTN1,ASCL1,RCOR3,ATP1A2,DKK3,SON,B3GALT2,KIF21B,CAB39,ZSWIM8,EMC1,DNER,NAP1L2,C11orf87,AJAP1,MLC1,VAMP1,SYT4,KAZN,TMEM136,ATF7,ZEB1,AZIN2,CAMK2G,CECR2,TMEM151B,VSTM2A,NUMA1,GRIA2,GRIA4,CYB561A3,OPCML,TGFBR3,USP2,GUCY1A1,CELF3,ZFP91,KCNK10,REPS2,HPS5,CDC42,RBFOX2,MAGI1,PDE1A,PDE4B,SCRG1,PFKFB3,MS4A7,VAV2,CELF5,SLC25A27,P2RY12,NSD2,FAT3,FEZ2,MICAL2,DZIP3,FMN2,SPIRE1,ZNF385B,SYNC,LRRTM3,ELMO1,MAGI2,KCNA4,PTPRD,PTPRZ1,NTM,KCNJ10,KCNK1,SNX27,DLG2,DLG3,DNAH9,DNM2,SLC17A6,PLEKHB2,SLC25A18,FAM13C,DTNA,BSDC1,RFX5,PIANP,SLC4A10,C2orf80,TMEM100,UEVLD" MicroRNA hsa-miR-2113:mirSVR_lowEffct hsa-miR-2113:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.93E-38 1.59E-34 5.95E-37 5.46E-36 108 1881 "MAP6,ACLY,TMEM74,LGR4,ARID1A,CSMD3,CLIP1,RTN1,DSCAML1,ADD3,ERMN,GPR158,KIAA1109,LRRC7,ASIC4,FHL1,CDC42BPA,ANK2,ANK3,PPFIA1,ITSN1,DGKZ,SLITRK3,LRRC4C,ZNF365,MSR1,LRRC55,SLC8A3,NSG2,DACH2,SPHKAP,SLIT1,NAXD,RCOR3,PHYHIPL,SOX5,KIF21B,ILDR2,ZSWIM8,B4GALNT1,ADAM15,NCAM1,CLASP2,NELL1,KIRREL3,NEUROD1,GNAS,WWC1,TBX15,VWC2,PTBP2,NUDT21,GRIA2,GRID1,RFFL,ADAMTS8,TMEM25,GUCY1A1,ATG4C,REPS2,CDC42,PADI2,PCDH9,RBFOX2,PDE1C,PDE4B,PDYN,ANO5,CASC2,TUB,TLX1,KIAA1549L,ST8SIA5,CELF5,BTF3L4,CHD1L,PPP2R5C,RGS6,MICAL2,PLD5,MASP1,BRINP3,ZBTB16,RIMS3,PLPPR5,PLPPR1,CADM2,LRP8,BLOC1S6,ZC3H11A,KCNA1,PTPRE,SV2A,RABGAP1L,ARNT2,KCNK2,KCNQ2,FAM13C,DTNA,ABCC9,TTLL7,SEC61A2,SSPN,ABI2,FGFBP3,ELAVL3,ELAVL4,UEVLD" MicroRNA hsa-miR-888:mirSVR_lowEffct hsa-miR-888:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.96E-38 1.60E-34 5.98E-37 5.49E-36 111 1986 "RTN3,ACTN2,ECSIT,ARID1A,ADAR,SLITRK1,WAC,NLGN4X,LRRTM4,KIAA1109,SEMA6A,SLC30A10,SELL,SGIP1,ANXA7,PKP4,PPM1E,DOCK10,NTNG1,GAS7,CACHD1,AQP4,ZNF365,PKNOX2,ARHGAP5,YPEL4,GPR153,SLCO1A2,TMEM108,SNAP25,SOX1,B3GALT2,SOX5,NAP1L2,NFASC,COLGALT2,STOX1,DCAF5,NEUROD1,ZNF638,OS9,WSCD1,GPM6A,CACNA1E,DDR1,PTBP2,SYT6,GRIA4,RFFL,GPR88,CYB561A3,GRM3,CRB1,PTPN5,ATG4C,PAX6,REPS2,PADI2,PCDH8,DCLK1,TPM3,PDE3B,ZMYND8,HMGB1,CASC2,TMEFF2,CADM1,NRXN1,ANLN,CCSER2,ST8SIA5,NXPH1,CHD1L,PNKD,MICAL2,OSBPL3,PRKAB2,DZIP3,RAB39A,USP54,KIAA0408,WBP1L,ANKS1B,SPIRE1,TUBB2B,PTCH1,ITGAV,PMEPA1,CADM2,SHD,KCNA1,OLFM3,PCDH15,DLG2,KIF2A,PLEKHB2,FAM66C,PARP11,RASGRF1,GNE,DBX2,ZYG11B,INSYN2,PHC2,SH3GLB1,RERGL,ARHGAP12,CBLN2,SLC4A10,YY1AP1,EPB41L2" MicroRNA hsa-miR-376a:mirSVR_lowEffct hsa-miR-376a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.44E-38 1.86E-34 6.92E-37 6.35E-36 100 1614 "MBP,CNTNAP3,RTN3,MEG3,ATAT1,ADAR,GALNT13,ERMN,TUBB4A,NLGN4X,AGT,FGF1,PLA2G6,FGF14,BCAR3,FOXG1,SFPQ,ANK3,PPFIA1,ANXA7,PKP4,PPM1E,DGKD,NLGN1,MSR1,MSRA,ARHGAP5,SLC8A3,DACH2,MTR,ASTN1,TMEM108,ATM,PALLD,SON,WDTC1,ENKUR,C11orf87,CLASP2,STOX1,ADHFE1,NEUROD1,SEPT3,GLS,LUZP2,GNAS,UNC5D,WWC1,TMEM136,ATF7,CACNA1E,CACNB2,PTBP2,GRIA2,GRIK3,GRM3,TGFBR3,CELF3,ZFP91,PAH,MAEL,PAX6,C1orf94,PCDH8,DCLK1,PDYN,TUB,ZFYVE9,NEGR1,A2ML1,OPALIN,ST8SIA5,SLC36A4,FAT3,PTPA,MICAL2,RBPJ,DZIP3,FMN2,CMTM5,PLD5,PUM1,HES5,FAM131B,PTCH1,JAKMIP2,CADM2,LRP8,CEP170,MAGI2,SRGAP3,ARNT2,KCNK2,PEX5,DLG2,TMEM255A,FAM13C,ABI2,SLC4A10,EN2" MicroRNA hsa-miR-548u:mirSVR_highEffct hsa-miR-548u:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-38 2.01E-34 7.46E-37 6.84E-36 104 1749 "SYT9,LGR4,RTN3,MEG3,EYA1,IL17D,CLIP1,RTN1,ADD3,FABP7,SORCS1,AMER2,TOMM40L,SNX32,LRRC7,FOXM1,AMPH,PPFIA1,ITSN1,APBA2,MAGI3,SLITRK3,NLGN1,LRRC4C,MIER1,YPEL4,CCDC88A,SPHKAP,SLIT1,CAPRIN2,ASPH,SLN,NRG3,USP33,TNIK,NAP1L2,NPAS3,SPART,NCAM1,SMOC1,ERBIN,NELL1,NEUROD1,AJAP1,FAM168A,GLS,CAMSAP2,PRUNE2,GPM6A,ACSL6,CACNA1E,TCF7L2,TCF12,SYT6,GRIA4,GPR88,OLR1,TGFBR3,TMEM257,RBFOX2,MAGI1,PDE4B,ZMYND8,CASC2,MS4A7,NLGN3,MEAF6,PRRX1,POU3F2,CRLS1,PPP3CB,KCNT2,OSBPL3,ATRNL1,RIMS4,CTNND2,NOS1AP,PTCH1,DNAJC6,PLPPR1,CNIH3,PRTFDC1,MAGI2,ZC3H11A,KCNA2,OLFM3,KCNA4,PTPRD,PTPRE,PLPPR4,PTPRO,RABGAP1L,DLG2,TMEM255A,ABI1,DTNA,RTN4,SLC6A15,SYT15,RBM12,LPAR6,SLC4A10,EPB41L2,UEVLD" MicroRNA hsa-miR-20a*:mirSVR_highEffct hsa-miR-20a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.76E-38 2.04E-34 7.52E-37 6.90E-36 97 1518 "ACER3,ACLY,CNTNAP3,SYT9,ATAT1,ADD3,WAC,FCGR1A,CHST15,LRRC7,SFPQ,CDC42BPA,ANK3,APC,GPAM,CACHD1,JAKMIP3,ZNF365,MIER1,SFMBT2,RUFY2,DACH2,PDE8B,SLCO1A2,SPHKAP,SORCS3,SMARCE1,ATM,TMEM151A,EIF4G3,B3GALT2,SALL3,DNER,NAP1L2,NPAS3,COLGALT2,NDUFA5,ZNF302,DCAF5,RGL1,NEUROD1,AJAP1,PCDH11X,CAMSAP2,WWC1,GPM6A,VWC2,GRID1,GRIK2,AIFM1,CDC42,HMGB1,CA14,CASC2,TLX1,NRXN2,FTO,SPATA6,NSD2,MFSD4A,POU3F2,CHD1L,SF1,TENM4,RGS6,NKAIN4,ATRNL1,RBPJ,DOCK7,MAPK10,MASP1,TOX,KIAA0513,TOMM20,PTCH1,DNAJC6,PTHLH,CADM2,CNIH3,PRTFDC1,KCNA2,PTPRE,SV2A,KCNK2,PCDH15,DLG2,KLRC3,FAM66C,GOPC,ABCC9,RET,RGS7,SLC39A12,SSPN,RPRD1A,FGFBP3,SLC4A10" MicroRNA hsa-miR-526a:mirSVR_lowEffct hsa-miR-526a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-38 2.16E-34 7.84E-37 7.20E-36 99 1584 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,NTNG1,SORBS1,ST3GAL3,SHTN1,AQP4,MIER1,LRRC55,SLC8A3,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,ACBD5,RNF14,PPP2R5C,PRKAB2,MAPK10,FAM131B,NOS1AP,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,RABGAP1L,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,TTLL7,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-518d-5p:mirSVR_lowEffct hsa-miR-518d-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-38 2.16E-34 7.84E-37 7.20E-36 99 1584 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,NTNG1,SORBS1,ST3GAL3,SHTN1,AQP4,MIER1,LRRC55,SLC8A3,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,ACBD5,RNF14,PPP2R5C,PRKAB2,MAPK10,FAM131B,NOS1AP,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,RABGAP1L,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,TTLL7,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-520c-5p:mirSVR_lowEffct hsa-miR-520c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-38 2.16E-34 7.84E-37 7.20E-36 99 1584 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,NTNG1,SORBS1,ST3GAL3,SHTN1,AQP4,MIER1,LRRC55,SLC8A3,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,ACBD5,RNF14,PPP2R5C,PRKAB2,MAPK10,FAM131B,NOS1AP,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,RABGAP1L,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,TTLL7,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-518f*:mirSVR_lowEffct hsa-miR-518f*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-38 2.16E-34 7.84E-37 7.20E-36 99 1584 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,NTNG1,SORBS1,ST3GAL3,SHTN1,AQP4,MIER1,LRRC55,SLC8A3,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,ACBD5,RNF14,PPP2R5C,PRKAB2,MAPK10,FAM131B,NOS1AP,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,RABGAP1L,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,TTLL7,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-640:mirSVR_lowEffct hsa-miR-640:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.42E-38 2.39E-34 8.67E-37 7.96E-36 90 1301 "ABAT,SYT9,RCSD1,LDLRAD3,CSMD3,ADAR,KLHL32,SORCS1,TMEM156,SNX30,SCN3A,LRRC7,FHL1,GOLGA7B,MOBP,SOX6,NTNG1,DGKD,SLITRK3,PAAF1,MIER1,SLC1A6,MSR1,ARFGAP2,NSG2,SLIT1,ASPH,DKK3,MYT1L,SOX5,NMNAT2,ARPP21,TTLL9,NPAS3,ALDH1L1,GJB1,ADHFE1,ARHGEF7,GLS,PCDH11X,ZNF638,LUZP2,DCLK2,CAMTA1,BTRC,ATF7,CACNB2,PTBP2,GRIA1,SPX,MFSD2A,REPS2,DCLK1,TPM3,PIRT,BEST3,CASC2,MS4A7,JAM2,KIAA1549L,OPALIN,NXPH1,MFSD4A,CHD1L,ATRNL1,NCAN,PRKACB,CMTM5,NRSN1,EDRF1,ECE2,MASP1,ZNF385B,PTHLH,LRP8,CDH20,SMG7,TMCC2,DLG3,CAB39L,WIPF2,PLEKHB2,FAM66C,SLC25A18,ABCC9,CRTAC1,NUP214,RET,FAM135B,SLC4A10" MicroRNA hsa-miR-519a:mirSVR_lowEffct hsa-miR-519a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.95E-38 2.68E-34 9.68E-37 8.88E-36 103 1721 "EPS8,MAP6,ACTN2,LDLRAD3,SLC25A25,CLIP1,WAC,SORCS1,AMER2,TRIM46,SGIP1,CDC42BPA,MAGI3,GPAM,TACC2,CLSTN1,MIER1,ARHGAP5,SHANK2,TAGLN3,MTR,SORCS3,SNAP25,TNIK,KIF21B,IDI2-AS1,GART,DNER,NAP1L2,NFASC,BCL2L2,NDUFA5,AJAP1,NFIA,MLC1,NHLH1,UNC5D,BTRC,TMEM136,GPM6A,FAM69C,CACNA1E,ZEB1,AZIN2,NUDT21,CAMK2G,SYT6,GRIA1,CRB1,MFSD2A,GUCY1A1,ZFP91,KCNK10,PAX6,REPS2,PTGDR2,LGI1,PFKFB3,CASC2,TUB,MS4A7,DUSP26,PIK3CD,CELF5,PRRX1,IFFO1,CNRIP1,MFSD4A,PNKD,KCNT2,FEZ2,ATRNL1,PRKCZ,SYNC,PRDM2,HP1BP3,CEP170,MAGI2,ZC3H11A,KCNA1,OCIAD1,PTPRD,KCNA6,PTPRE,SRGAP3,PCDH15,NAV2,DLG2,HS3ST4,C12orf4,SLC25A18,ABI1,GOPC,FAM13C,DTNA,PAK5,BSDC1,SFXN5,SLC39A12,RPRD1A,BSCL2,TMEM100,EPB41L1" MicroRNA hsa-miR-574-5p:mirSVR_lowEffct hsa-miR-574-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-38 2.71E-34 9.75E-37 8.94E-36 104 1755 "RABEPK,SERPINA3,ABAT,MAP6,SYT9,MEG3,ADGRV1,MRVI1,CSMD2,WLS,ADAR,GALNT13,SCN4B,FGF1,BCAR3,SOX6,ANK1,ANK2,PPM1E,GPAM,ST3GAL3,JAKMIP3,RPH3A,CADPS,CGREF1,SCG3,ASPH,MEGF11,KIF21B,NMNAT2,ARPP21,DNER,NCDN,SEPT3,AJAP1,ARHGEF7,GLS,CASTOR3,PCDH11X,ASTN2,LUZP2,KAZN,GPM6B,DDR1,TCF12,DIRAS1,CECR2,BRSK2,GRID1,GRIK2,GUCY1A1,CELF3,TMEM257,ZDHHC22,ZFP91,PAX6,PTGDR2,LGI1,PDE1A,PDE1C,GPR37L1,ANO5,LRTM2,TUB,DLGAP3,NEGR1,A2ML1,P2RY12,IFFO1,ATCAY,ACBD5,PNKD,CRMP1,SNCAIP,PHACTR3,PRKACB,FMN2,PLD5,NRSN1,PUM1,PROX1,PTHLH,COPS7A,BLOC1S6,PTPRZ1,AK5,KCNK1,PCDH15,DLG2,DLG3,NKAIN1,KIF2A,WIPF2,SLC25A48,ATN1,DSCAM,DTNA,RGR,JMJD1C,INSYN2,PIANP,PRRT4,EPB41L2,UEVLD" MicroRNA hsa-miR-106b:mirSVR_highEffct hsa-miR-106b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.50E-38 2.98E-34 1.07E-36 9.79E-36 97 1525 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASTN1,ATP1A2,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,NPAS3,SPART,LMO3,SMOC1,ERBIN,RGL1,ADHFE1,ARHGEF7,DCLK2,CAMTA1,LINC00839,TMEM25,ZFP91,HPS5,TNS1,CDH10,LGI1,PDE3B,BEST3,ZFYVE9,UBTF,CCSER2,SULT4A1,SLC25A27,PRRX1,SPATA6,ACBD5,CNRIP1,PPP3CB,FEZ2,CHD5,PRKACB,DOCK7,PKN2,CTNND1,NRSN1,PSD,ANKS1B,TOMM20,SIRPA,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,PTPRO,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,SFXN5,EFNA3,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-874:mirSVR_lowEffct hsa-miR-874:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.56E-38 3.01E-34 1.08E-36 9.87E-36 96 1493 "EPS8,ABAT,ZFYVE27,CDHR1,SRARP,DUSP27,WLS,RTKN,DSCAML1,GRAMD1B,TOMM40L,SNX32,FGF1,HPCAL4,MOBP,ANK2,ANK3,APBB1,NTNG1,DGKD,SHTN1,LRRC55,DACH2,LGI3,NAXD,ASTN1,B3GAT1,ZSWIM8,AHCYL1,ENKUR,ADAM15,NPAS3,C11orf87,GFAP,HEPN1,KIRREL3,ADHFE1,AJAP1,ACSBG1,KAZN,NODAL,MYRF,UNC5D,PSRC1,CNTN2,TBX15,CACNA1E,ZEB1,CAMK2G,TMEM151B,CCKBR,USP2,ZDHHC22,PADI2,LILRA4,PFKFB3,SEMA5B,UBTF,NMT2,CCSER2,CABP1,CELF5,PRRX1,ATCAY,MFSD4A,POU3F2,MED1,PTPA,SNCAIP,NCAN,FMN2,KIAA1755,PRKCG,PKN2,USP54,CTNND2,SYTL2,PRDM2,HP1BP3,CDH20,PTPRD,SV2A,KCNJ9,KCNJ10,CCDC3,PCDH15,RAB3IL1,DNM2,RASGRF1,BSDC1,ZNF248,SYT15,RNF220,PIANP,VWA5A,BAALC" MicroRNA hsa-miR-4330:mirSVR_lowEffct hsa-miR-4330:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.42E-38 4.02E-34 1.43E-36 1.31E-35 104 1763 "MAG,TTYH1,ACLY,DUSP27,RCSD1,KCNIP2,KLHL32,ADD3,FABP7,LINC00461,LRRC7,ASIC4,BCAR3,MOBP,ANK1,APC,NTNG1,API5,AQP4,CCDC88A,NSG2,SORCS3,RCOR3,C10orf105,ADGRA1,ALDH4A1,ATM,ATP1A2,B4GALNT1,ARPP21,NCAM1,CLASP2,ALDH1L1,ADHFE1,AJAP1,MLC1,ARHGEF7,CASTOR3,PCDH11X,SEMA4A,GNAS,DDHD2,UNC5D,TMEM136,ANO4,LILRA1,DIRAS1,NUDT21,SYT6,GRIA4,GRID1,OPCML,CRB1,LEFTY2,ZFP91,PAH,ATG4C,PCDH9,CDH8,DCLK1,RBFOX2,TPM3,MAGI1,PDE2A,PDE3B,PIRT,BEST3,HMGB1,CASC2,JAM2,A2ML1,CCSER2,ST8SIA5,CNTN1,MEAF6,NSD2,PPP3CB,KCNT2,MICAL2,CHD5,PHACTR3,NRSN1,PUM1,EDRF1,RIMS3,GON4L,PRDM2,COPS7A,SRGAP3,RAB5B,KLRC2,TMEM255A,DNM2,ABCC9,ZNF248,VANGL2,SEC61A2,SFXN5,ABI2,LPAR6,SLC4A10,EN2,EPB41,EPB41L1" MicroRNA hsa-miR-1979:mirSVR_lowEffct hsa-miR-1979:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.84E-38 4.25E-34 1.51E-36 1.38E-35 110 1972 "RABEPK,SYT9,LGR4,RTN3,MEG3,ATAT1,CSMD2,RTKN,NDRG2,ADAR,FABP7,GRAMD1B,DRAXIN,TOMM40L,FGF1,SEMA6A,ASIC4,BCAR3,MOBP,MOG,PDZD4,SGIP1,ANXA7,GPAM,SORBS1,ST3GAL3,LRRC55,PKNOX2,SLC8A2,NSG2,SLC14A1,KBTBD12,ATP1A2,EIF4G3,PALLD,MEGF11,USP33,SON,WDTC1,ZCCHC24,KIF21B,ENKUR,TTLL9,FXYD6,BCL2L2,ALDH1L1,DCAF5,GJB1,PHLDB1,SEPT3,TBX15,ATF7,CACNA1E,DDR1,CACNB2,TCF7L2,HAP1,CAMK2A,CAMK2G,BRSK2,GRIK3,CYB561A3,TGFBR3,ZDHHC22,CD81,TNR,RBFOX2,LGI1,PDE1C,HMGB1,ANO5,CHRM1,CASC2,CHRNB2,CADM1,CPT1C,CCSER2,OPALIN,C11orf49,NSD2,MFSD4A,CHD1L,FMN2,KIAA1755,NRSN1,MASP1,SPIRE1,TOMM20,COPS7A,MED24,KCNA1,OCIAD1,PLPPR4,PTPRO,KCNJ10,DLG2,CAB39L,HS3ST4,RALGDS,GOPC,RASGRF1,ABCC9,CRTAC1,RFX4,ZNF248,SH3GLB1,GPR61,ABI2,FGFBP3,C2orf80" MicroRNA hsa-miR-516b*:mirSVR_lowEffct hsa-miR-516b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.08E-38 4.92E-34 1.73E-36 1.59E-35 109 1940 "SERPINA3,ABAT,PRR5L,ASIC1,ACLY,SYNDIG1,CEND1,ATAT1,CSMD3,ADCY2,AMER2,FCGR1A,TOMM40L,TESK2,FGF14,GOLGA7B,FOXM1,CDC42BPA,CNIH2,ITSN1,APBB1,NTNG1,SORBS1,CACHD1,URGCP,LRRC55,SLC8A2,NSG2,CGREF1,PDE8B,CSPG5,NAXD,SLN,RCOR3,SNCB,MEGF11,GABBR1,SCN3B,MYH7,NEK6,SPART,RCOR2,NELL1,ADHFE1,PHLDB1,SEPT3,AJAP1,PCDH11X,GNAS,NODAL,UNC5D,WWC1,TMEM136,ATF7,TCF7L2,TCF12,DIRAS1,AZIN2,PTBP2,EML4,PCDHGA3,GRIA1,CYB561A3,TNFRSF1B,PCDH8,PCDH9,LGI1,PCSK2,CA14,ANO5,PFKFB3,TUB,MS4A7,GDAP1L1,OPALIN,MEAF6,FAT3,CP,POU3F4,CHD1L,RNF14,PPP3CB,OSBPL3,PLD5,ECE2,MASP1,ZBTB16,TOX,WBP1L,PLPPR5,PTCH1,BDNF-AS,CADM2,ELMO1,ZC3H11A,PTPRD,KCNA6,SMG7,SV2A,SRGAP3,KCNN3,WIPF2,PID1,GNE,FAM13C,BSDC1,RFX4,EN2,RPE65" MicroRNA hsa-miR-516a-3p:mirSVR_lowEffct hsa-miR-516a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.08E-38 4.92E-34 1.73E-36 1.59E-35 109 1940 "SERPINA3,ABAT,PRR5L,ASIC1,ACLY,SYNDIG1,CEND1,ATAT1,CSMD3,ADCY2,AMER2,FCGR1A,TOMM40L,TESK2,FGF14,GOLGA7B,FOXM1,CDC42BPA,CNIH2,ITSN1,APBB1,NTNG1,SORBS1,CACHD1,URGCP,LRRC55,SLC8A2,NSG2,CGREF1,PDE8B,CSPG5,NAXD,SLN,RCOR3,SNCB,MEGF11,GABBR1,SCN3B,MYH7,NEK6,SPART,RCOR2,NELL1,ADHFE1,PHLDB1,SEPT3,AJAP1,PCDH11X,GNAS,NODAL,UNC5D,WWC1,TMEM136,ATF7,TCF7L2,TCF12,DIRAS1,AZIN2,PTBP2,EML4,PCDHGA3,GRIA1,CYB561A3,TNFRSF1B,PCDH8,PCDH9,LGI1,PCSK2,CA14,ANO5,PFKFB3,TUB,MS4A7,GDAP1L1,OPALIN,MEAF6,FAT3,CP,POU3F4,CHD1L,RNF14,PPP3CB,OSBPL3,PLD5,ECE2,MASP1,ZBTB16,TOX,WBP1L,PLPPR5,PTCH1,BDNF-AS,CADM2,ELMO1,ZC3H11A,PTPRD,KCNA6,SMG7,SV2A,SRGAP3,KCNN3,WIPF2,PID1,GNE,FAM13C,BSDC1,RFX4,EN2,RPE65" MicroRNA hsa-miR-27b:mirSVR_highEffct hsa-miR-27b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.93E-38 5.38E-34 1.89E-36 1.73E-35 97 1536 "SYT9,MEG3,EYA1,SLITRK1,ADD3,GRAMD1B,ADORA1,ADORA3,TOMM40L,TESK2,KIAA1109,FGF1,FGF14,SEMA6A,MOBP,TRIM46,ERICH3,ANK2,ANK3,PKP4,APBA2,MAGI3,GPAM,PAAF1,ARFGAP2,DACH2,ASPH,RCOR3,SNAP25,ATP1A2,TNIK,CAB39,NEK6,TTC9B,KIF1B,NAP1L2,NCAM1,COLGALT2,STOX1,ZNF302,ERBIN,GLS,ZNF638,DDHD2,CAMTA1,CACNA1A,GPM6A,NPPA,CACNB2,ZEB1,VSTM2A,GRIA4,TF,CRB1,TGFBR3,INA,MAEL,PCDH9,MAGI1,ZNF384,PRMT8,CIART,ADGRG1,CASC2,MS4A7,CADM1,NRXN1,DNAJC12,BEST1,POU3F2,CHD1L,PNKD,CRMP1,VCAN,PKN2,EDRF1,TOX,PTAFR,DNAJC6,CA10,PLPPR1,LRP8,KCNK2,CAB39L,KLRC2,DTNA,RET,JMJD1C,FAM135B,VANGL2,LPAR6,ARHGAP12,SLC4A10,C2orf80,EN2,EPB41,RCAN2" MicroRNA hsa-miR-25:mirSVR_lowEffct hsa-miR-25:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-37 6.24E-34 2.18E-36 2.00E-35 103 1738 "EPS8,C1orf194,ACER3,LGR4,SYNDIG1,ADARB2,ADD3,NLGN4X,GPR158,TESK2,LINC00461,FGF1,BCAR3,UNC79,FOXG1,AMPH,ANK2,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,SORCS3,ASTN1,TMEM108,ADGRA1,ATP1A2,GABBR1,MYT1L,AHCYL1,NMNAT2,ENKUR,NAP1L2,ERBIN,NEUROD1,NFIA,GLS,VAMP1,ZNF638,DCLK2,NKX2-2,DDHD2,CDK5R2,BTRC,KLHL4,TBX15,GPM6B,ZEB1,EML4,VSTM2A,GRIA4,GRIK2,TMEM257,CDC42,PCDH8,PCDH9,PTGDR2,LGI1,TPD52,PIRT,PDYN,HMGB1,ANO5,CHGA,CASC2,JAM2,CADM1,KIAA1549L,BTF3L4,SPATA6,CHD1L,CRLS1,PPP2R5C,NKAIN4,NCAN,PHACTR3,PRKAB2,PRKACB,DZIP3,PRKCG,PKN2,ECE2,NOS1AP,ZNF385B,SIRPA,DNAJC6,HP1BP3,KCNA1,OCIAD1,NTM,KCNMA1,SLC25A48,C12orf4,ABI1,JMJD1C,INSYN2,RLBP1,RERGL,ABI2,FGFBP3" MicroRNA hsa-miR-3128:mirSVR_lowEffct hsa-miR-3128:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-37 6.46E-34 2.25E-36 2.07E-35 107 1876 "SDE2,ZFYVE27,MAP6,PAQR6,MEG3,ADGRV1,IL17D,KCNIP2,ADCY2,NLGN4X,TOMM40L,GPR158,KIAA1109,DISP3,HPCAL4,SOX6,FOXM1,ERICH3,ANK3,CNIH2,ANXA7,APBA2,APC,GPAM,JAKMIP3,USP16,KIAA1614,RPH3A,MSR1,SLC8A3,CGREF1,NAXD,SLN,ASTN1,EIF4G3,ATP2B2,PALLD,SOX5,ZSWIM8,AHCYL1,IDI2-AS1,ADAM15,KIF1B,SPART,ZNF302,GFAP,ARHGEF7,RHBDL3,ZNF638,ASTN2,ADGRL3,ANO4,PRUNE2,GPM6B,TCF12,PTBP2,NUDT21,CAMK2A,TMEM151B,VXN,CYB561A3,CRB1,ZDHHC22,REPS2,PADI2,PCDH8,PTGDR2,LGI1,PDE1C,PIRT,HMGB1,ASIC3,NMT2,OPALIN,DNAJC12,PRRX1,NSD2,MFSD4A,PNKD,SF1,FEZ1,PLCH2,NCAN,IGSF1,NRSN1,WBP1L,ANKS1B,PSMD13,PTHLH,ELMO1,HP1BP3,KCNA1,PLPPR4,KCNK2,DLG2,RASGRF1,RTN4,NUP214,RET,RFX5,EEF1A2,SEC61A2,SIDT2,RBM12,ELAVL3,EPB41L2,RASGRP2" MicroRNA hsa-miR-1909:mirSVR_lowEffct hsa-miR-1909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-37 6.50E-34 2.26E-36 2.07E-35 108 1911 "TTYH1,ASIC1,ACHE,RTN3,CEND1,ATAT1,MDM4,ADARB2,ERMN,GRAMD1B,TUBB4A,FOXRED2,FCGR1B,TOMM40L,HOGA1,PLA2G6,ASIC4,PDZD4,TRIM46,SELL,ERICH3,CNIH2,PPFIA1,ITSN1,APBB1,ZNF365,KIAA1614,URGCP,MADD,YPEL4,MT3,ASCL1,LGI3,ARFGAP1,RCOR3,TMEM108,ADGRA1,IGSF9B,ATP1A3,DKK3,GABBR1,ZCCHC24,SOX10,ZSWIM8,B4GALNT1,LHFPL4,COLGALT2,BCL2L2,NCDN,HEPN1,ADHFE1,PHLDB1,FAM168A,VAMP1,RHBDL3,KAZN,CAMTA1,MMD2,WWC1,PRUNE2,NEU4,DIRAS1,NRGN,HAP1,CAMK2G,GRIA1,GRIA4,GPR88,LEFTY2,CD81,RBFOX2,HRH3,SEZ6L,LGI1,PIRT,NTSR2,HPSE2,CHRM1,PLEKHB1,HPCA,DLGAP3,CADM1,CAMKV,UBTF,PLXNB3,BEST1,MED1,PNKD,PPP2R5C,PLCH2,RBPJ,IGSF1,PUM1,MASP1,DPYSL5,PMEPA1,RGMA,SMG7,PARD6A,KCNJ10,SLC25A48,RAP1GAP,ATN1,VANGL2,CACNG7,ELAVL3,OLIG2,EPB41L2" MicroRNA hsa-miR-367:mirSVR_lowEffct hsa-miR-367:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-37 7.96E-34 2.76E-36 2.53E-35 104 1777 "EPS8,C1orf194,ACER3,LGR4,SYNDIG1,EYA1,ADARB2,SLITRK1,ADD3,ERMN,FCGR1A,TESK2,LINC00461,FGF1,BCAR3,UNC79,FOXG1,AMPH,ANK2,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,ARHGAP5,SORCS3,ASTN1,ALDH4A1,GABBR1,MYT1L,AHCYL1,ENKUR,ERBIN,NFIA,GLS,DCLK2,NKX2-2,DDHD2,CDK5R2,BTRC,KLHL4,TBX15,GPM6B,ZEB1,TCF12,EML4,GRIK2,TMEM257,CDC42,PCDH8,PCDH9,TPD52,PIRT,PDYN,CHGA,CASC2,TMEFF2,JAM2,CADM1,KIAA1549L,NEGR1,BTF3L4,SPATA6,CHD1L,PPP2R5C,PPP3CB,RGS6,MICAL2,PHACTR3,PRKAB2,PRKACB,DZIP3,PRKCG,PKN2,PRKCZ,NOS1AP,ZNF385B,LRRTM3,SIRPA,PRDM2,HP1BP3,KCNA1,OCIAD1,NTM,KCNK1,KCNMA1,SLC25A48,DPP6,C12orf4,ABI1,SLC6A15,RET,JMJD1C,INSYN2,RLBP1,SH3GLB1,RPRD1A,RERGL,ABI2,FGFBP3,RCAN2" MicroRNA hsa-miR-422a:mirSVR_lowEffct hsa-miR-422a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.54E-37 8.32E-34 2.87E-36 2.63E-35 102 1710 "SERPINA3,SYNDIG1,MRVI1,ADAR,ADCY2,ADD3,ADORA1,SNX32,FGR,SOX6,CDC42BPA,ITSN1,APBA2,NTNG1,MAGI3,CCDC80,DGKZ,ZCCHC17,PAAF1,ZNF365,MSR1,MSRA,LRRC55,PKNOX2,SLC8A2,SLC8A3,SPHKAP,ASPH,KBTBD12,B3GAT1,NRG3,DKK3,WDTC1,ZCCHC24,CAB39,NMNAT2,B4GALNT1,NFASC,SMOC1,ADHFE1,ARHGEF7,ZNF638,DCLK2,DDHD2,MMD2,ANO4,TBX15,WSCD1,GPM6B,TCF7L2,CLEC9A,TCF12,PTBP2,CAMK2A,VXN,SYT6,NUMA1,AKNA,GPR88,FBXL16,DAAM2,TNFRSF1B,PCDH9,DCLK1,LINC01102,GPR37L1,HMGB1,ANO5,CASC2,TUB,GDAP1L1,NMT2,CCSER2,OPALIN,CELF5,MFSD4A,CHD1L,SF1,CRLS1,TENM4,KCNT2,ATRNL1,NCAN,EDRF1,SIRPA,DNAJC6,KCNK2,KCNN3,PEX5,DLG2,OLIG1,DNM2,RASGRF1,L1CAM,NUP214,FAM135B,VANGL2,RNF220,SSPN,SLC4A10,EN2,SEZ6" MicroRNA hsa-miR-3155:mirSVR_lowEffct hsa-miR-3155:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-37 8.79E-34 3.02E-36 2.77E-35 110 1988 "LOC100128239,ACLY,SYT9,ATAT1,LDLRAD3,ARID1A,MDM4,KCNIP2,ADD3,GRAMD1B,ADORA1,SCN3A,LRRTM4,LINC00461,ASIC4,MOG,ERICH3,ITSN1,SLITRK3,BCAN,SORBS1,BCAS1,SLC8A3,DACH2,CADPS,SNCB,ATP1A2,USP33,MYT1L,CADM3,MYH7,ARPP21,NFASC,BCL2L2,GFAP,KIRREL3,NEUROD1,AJAP1,ARHGEF7,VAMP1,DCLK2,WWC1,ANO4,AZIN2,NUCB1,TF,CCKBR,INA,P2RX7,TNR,CDH8,LINC01102,ZMYND8,CHGA,PFKFB3,PLEKHB1,HERC2P3,CAMKV,SEMA5B,PIK3CD,NMT2,CCSER2,TJP2,FADS2,MEAF6,SLC25A27,BEST1,PRRX1,NSD2,NXPH1,CHD1L,PTPA,NKAIN4,ATRNL1,PLCH2,CMTM5,PLPP4,ECE2,NOS1AP,WBP1L,PHYHIP,SIRPA,PRDM2,COPS7A,CSDE1,BLOC1S6,SV2A,KCNMA1,PEX5,DLG2,HS3ST4,DNAH9,DPP6,SUSD4,GOPC,DBX2,DTNA,SLC6A15,ZYG11B,CAMK1G,NUP214,RET,FAM135B,PHC2,SSPN,RBM12,BSCL2,RPE65,PRRT4,EPB41L2" MicroRNA hsa-miR-659:mirSVR_lowEffct hsa-miR-659:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-37 8.97E-34 3.07E-36 2.82E-35 107 1883 "RABEPK,TTYH1,SERPINA3,SDE2,LDLRAD3,ARID1A,SLC25A25,CSMD3,ADCY2,FOXRED2,CHST15,TESK2,LRRTM4,FHL1,HPCAL4,SOX6,SGIP1,ANK1,USP28,NTNG1,MAGI3,GPAM,DGKD,SORBS1,API5,ZNF365,MSR1,LRRC55,ARHGAP5,CCDC88A,SLC14A1,DACH2,BRINP2,MTR,NRG3,EIF4G3,PHYHIPL,PALLD,MEGF11,SON,WDTC1,SOX1,IDI2-AS1,ADHFE1,ZNF638,LUZP2,DCLK2,UNC5D,CACNA1A,VWC2,RFFL,GRIK2,CRB1,TGFBR3,TNR,PCDH9,ARHGAP19,TPD52,PIRT,ZMYND8,OPALIN,SULT4A1,BEST1,PRRX1,NXPH1,ETNPPL,MED1,CRMP1,SNCAIP,RGS6,OSBPL3,VCAN,RBPJ,DOCK7,FMN2,PKN2,TOX,KIAA0513,ANKS1B,SYNC,LRRTM3,PLPPR1,BDNF-AS,ITIH2,CADM2,PRDM2,HP1BP3,BLOC1S6,ZC3H11A,PTPRD,PLPPR4,PTPRZ1,SV2A,SRGAP3,KCNJ10,CCDC3,KCNK2,NAV2,SLC17A6,SLC25A18,SUSD4,GNE,USH1C,SSPN,CBLN2,RPE65,EPB41" MicroRNA hsa-miR-377*:mirSVR_lowEffct hsa-miR-377*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-37 1.09E-33 3.71E-36 3.40E-35 99 1615 "MAP6,ACHE,MBP,SYT9,MEG3,CSMD3,CHST15,FGF14,BCAR3,MOBP,FOXG1,CNIH2,ITSN1,ANXA7,MAGI3,CCDC80,BCAN,CACHD1,ST3GAL3,AQP4,SFMBT2,LRRC55,SLC8A3,NSG2,SLC14A1,EIF4G3,PHYHIPL,DKK3,SCN3B,ZCCHC24,SOX10,ENKUR,NCAM1,NDUFA5,RGL1,NFIA,ZNF638,LUZP2,KAZN,GNAS,CAMTA1,CDK5R2,UNC5D,ADGRL3,KLHL4,NPPA,TCF7L2,EML4,BRSK2,GRIA2,GRIA4,GRIN1,SPX,FBXL16,PADI2,PCDH8,CDH8,PDE1C,GPR37L1,NTSR2,PLXNB3,PMP2,SLC25A27,SPATA6,ACBD5,MFSD4A,CRLS1,SNCAIP,PPP3CB,NKAIN4,OSBPL3,NCAN,DZIP3,SDC3,USP54,ACY3,WBP1L,PLPPR5,TUBB2B,RGMA,OLFM3,OCIAD1,PLPPR4,KCNC1,KCNH1,NTM,PCDH15,PID1,RAD52,GNE,CAMK1G,JMJD1C,ATL1,SEC61A2,RPRD1A,CBLN2,YY1AP1,EPB41L2,BAALC" MicroRNA hsa-miR-370:mirSVR_lowEffct hsa-miR-370:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-37 1.15E-33 3.92E-36 3.60E-35 110 1994 "ASIC1,CDHR1,SYT9,ACTN2,FAM43B,RTKN,CHST15,TOMM40L,FGF14,TRIM46,CDC42BPA,USP28,APBA2,CACHD1,ST3GAL3,SFMBT2,MT3,NSG2,SLCO1A2,MTR,SORCS3,TMEM108,ATP1A2,WDTC1,B3GALT2,ILDR2,ZSWIM8,ENKUR,NEK6,ADAM15,KIF1B,FXYD6,CLASP2,ALDH1L1,NDUFA5,DCAF5,INKA2,PHLDB1,NEUROD1,MLC1,PCDH11X,ZNF638,KAZN,SEMA4A,GNAS,PSRC1,GOLGB1,ANO4,CACNB2,TCF7L2,TCF12,EML4,TMEM151B,VXN,NUMA1,CYB561A3,PTPN5,TMEM25,TJP1,TLL2,KCNK10,CDH8,TPM4,PDE1C,HMGB1,TMPRSS5,ASIC3,HNRNPK,HEPACAM,UBTF,VAV2,BEST1,MICAL2,VCAN,RBPJ,RAB39A,CTNND2,EDRF1,ECE2,BRINP3,WBP1L,TOMM20,PLPPR5,STMN4,PTPRE,KCNC1,KCNJ9,RABGAP1L,TMCC2,CCDC3,KCNK1,PCDH15,DLG2,CAB39L,NKAIN1,WIPF2,DNM2,ATN1,DTNA,RTN4,BSDC1,NUP214,PHC2,SYT15,RNF220,EN2,RPE65,EPB41L2,SEZ6,BAALC" MicroRNA hsa-miR-196a*:mirSVR_lowEffct hsa-miR-196a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-37 1.17E-33 3.98E-36 3.65E-35 104 1785 "RABEPK,SDE2,ZFYVE27,MBP,CNTNAP3,SYT9,MDM4,RTN1,FABP7,SLC44A5,LRRC7,UNC79,FOXG1,SOX6,TRIM46,CDC42BPA,ANK3,APBA2,NTNG1,JAKMIP3,SLC7A14,RUFY2,ARHGAP5,SLC8A2,SHANK2,IGSF9B,ATM,NRG3,ATP2B2,SCN3B,WDTC1,MYT1L,ZCCHC24,KIF21B,ZSWIM8,NMNAT2,ENKUR,EMC1,KIF1B,GART,DNER,NFASC,NCAM1,ERBIN,GFAP,GJB1,ADHFE1,NHLH1,DDHD2,KLHL4,TCF7L2,EML4,CCKBR,INA,P2RX7,GUCY1A1,DAAM2,TPM3,PDE3B,PRMT8,PIRT,GPR37L1,BEST3,CASC2,CADM1,KIAA1549L,NEGR1,PIK3CD,A2ML1,OPALIN,MEAF6,BEST1,IFFO1,NXPH1,POU3F2,PNKD,PPP2R5C,FEZ1,MICAL2,NCAN,DOCK7,KIAA1755,PLPP4,EDRF1,NOS1AP,WBP1L,TUBB2B,CNIH3,LRP8,ZC3H11A,OCIAD1,SRGAP3,RAB5B,PID1,RAD52,FAM66C,DPP6,GOPC,RASGRF1,FAM13C,BSDC1,ABCC9,ZNF248,RBM12" MicroRNA hsa-miR-3153:mirSVR_highEffct hsa-miR-3153:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-37 1.29E-33 4.36E-36 4.00E-35 92 1392 "ASIC1,RTN3,MRVI1,ATAT1,ARID1A,RTN1,SORCS1,TESK2,SFPQ,ITSN1,SH3GL2,MAGI3,SLITRK3,ST3GAL3,MIER1,RPH3A,CADPS,ASPH,ATP1A2,PHYHIPL,GABBR1,TNIK,SOX5,JPH4,KIF1B,NPAS3,LMO3,C11orf87,ADHFE1,PHLDB1,NEUROD1,GANAB,AJAP1,GNAS,BTRC,TMEM136,TBX15,CACNA1A,VXN,NUMA1,GRIA2,OLR1,LEFTY2,GUCY1A2,CDC42,IGSF21,TNR,PDE2A,PDE3B,PDE4B,ZMYND8,GPR37L1,TMEFF2,GDAP1L1,CADM1,KIAA1549L,NEGR1,FTO,CNTN1,CNRIP1,POU3F4,SF1,CRMP1,NCAN,PRKACB,DZIP3,FMN2,CTNND1,NRSN1,CA10,ITIH2,HP1BP3,CEP170,PTPRO,NTM,AK5,KCNK2,PCDH15,KCNMA1,RAB5B,PID1,DPP6,GOPC,DSCAM,ZYG11B,RET,VANGL2,RNF220,RPRD1A,FGFBP3,RAVER2,BSCL2" MicroRNA hsa-miR-30a:mirSVR_highEffct hsa-miR-30a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.50E-37 1.36E-33 4.56E-36 4.19E-35 106 1857 "MAP6,CDHR1,SYT9,RCSD1,ARID1A,CSMD3,GALNT13,CDC7,FABP7,SORCS1,ERMN,SCN3A,LINC00461,SLC30A10,FOXG1,ERICH3,ITSN1,DOCK10,APC,MAGI3,SORBS1,CACHD1,NLGN1,JAKMIP3,PAAF1,ZNF365,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,SMARCE1,RCOR3,NRG3,ATP2B2,SON,JPH4,KIF1B,NAP1L2,NPAS3,SPART,CLASP2,BCL2L2,RGL1,GLS,SYT4,GNAS,DDHD2,CAMTA1,ADGRL3,ANO4,PRUNE2,GPM6A,CACNB2,GPR19,EML4,CECR2,GRIA2,RFFL,GRM3,OMG,CRB1,USP2,TLL2,CELF3,PCDH9,LGI1,MAGI1,PIRT,ZMYND8,MS4A7,TMEFF2,PIK3CD,MICAL1,ACBD5,PNKD,OSBPL3,PRKACB,DOCK7,CTNND2,TOX,SPIRE1,TOMM20,LRRTM3,CA10,JAKMIP2,CEP170,CSDE1,MAGI2,BLOC1S6,KCNA2,PLPPR4,RABGAP1L,PARP11,RALGDS,PAK5,ABCC9,RGS7,TTLL7,RNF220,RPRD1A,RAVER2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-519c-3p:mirSVR_highEffct hsa-miR-519c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.72E-37 1.47E-33 4.94E-36 4.54E-35 97 1555 "CNTNAP3,MDM4,F3,RTN1,GALNT13,GPR158,HOGA1,TESK2,SCN3A,LINC00461,LRRC7,FGF14,FOXG1,MOG,ERICH3,USP28,ITSN1,SLITRK3,SYBU,API5,SHTN1,PAAF1,BCO1,RUFY2,MSR1,LRRC55,CCDC88A,NAXD,CAPRIN2,RCOR3,ATM,GABBR1,MYT1L,B3GALT2,SOX5,GAD2,B4GALNT1,ARPP21,SPART,C11orf87,CLASP2,SMOC1,ERBIN,NELL1,ADHFE1,NEUROD1,GANAB,GLS,ZNF638,SYT4,LUZP2,CAMTA1,CAMSAP2,MYRF,GRIA4,ADAMTS8,LINC00839,TGFBR3,HPS5,PDE3B,BEST3,TLX1,ZFYVE9,CCSER2,BTF3L4,PMS2,NSD2,CRLS1,PPP3CB,CHD5,DOCK7,NRSN1,PSD,ANKS1B,SIRPA,CA10,PTHLH,CSDE1,PLPPR4,KCNJ10,KCNK1,CAB39L,RAB5B,PID1,SLC25A48,SLC17A6,ATG16L1,ABCC9,SLC6A15,ZYG11B,RET,RFX5,SSPN,FGFBP3,ARHGAP12,RAVER2,UEVLD" MicroRNA hsa-miR-556-5p:mirSVR_lowEffct hsa-miR-556-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.30E-37 1.79E-33 5.97E-36 5.48E-35 96 1526 "SERPINA3,MBP,RCSD1,ATAT1,GRAMD1B,TESK2,LRRTM4,FGF1,PLA2G6,HPCAL4,PPFIA1,ITSN1,SORBS1,NLGN1,ST3GAL3,SHTN1,MIER1,RUFY2,DACH2,PDE8B,SPHKAP,NAXD,ASPH,NRG3,PHYHIPL,DKK3,GABBR1,SCN3B,USP33,MYT1L,KIF21B,CAB39,NMNAT2,CPLX2,NFASC,CLASP2,NDUFA5,GFRA1,RGL1,GNAS,BTRC,PRUNE2,CACNA1E,LRIT2,ZEB1,TCF12,DIRAS1,NUDT21,VXN,BRSK2,NEURL1,RBFOX2,SEZ6L,PDE2A,PRMT8,ADGRG1,CASC2,TUB,GDAP1L1,CADM1,KIAA1549L,PLXNB3,CELF5,BEST1,COL9A2,IFFO1,NXPH1,POU3F2,PPP2R5C,SNCAIP,TENM4,KCNT2,ATRNL1,NCAN,PHACTR3,RBPJ,DZIP3,PKN2,PLD5,MAPK10,TUBB2B,LRRTM3,CA10,PTPRE,PLPPR4,CCDC3,DLG3,RAB5B,SUSD4,DSCAM,DTNA,RTN4,ABCC9,ATL1,RPRD1A,ELAVL4" MicroRNA hsa-miR-502-3p:mirSVR_lowEffct hsa-miR-502-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-37 1.99E-33 6.63E-36 6.08E-35 89 1306 "ZFYVE27,LGR4,PAQR6,ADGRV1,RTN1,ADCY2,ADD3,ERMN,NLGN4X,TOMM40L,GPR158,SCN3A,LINC00461,ASIC4,MOBP,SOX6,USP28,ITSN1,MAGI3,SYBU,NLGN1,PAAF1,CLSTN1,SLC7A14,NSG2,SMARCE1,SNAP25,ATP1A2,DKK3,SON,WDTC1,MYT1L,JPH4,B4GALNT1,TTLL9,NFASC,ALDH1L1,NFIA,CAMTA1,CAMSAP2,MYRF,WWC1,ANO4,GPM6A,GPM6B,AZIN2,TMEM151B,VSTM2A,GRIA1,TGFBR3,TJP1,PAX6,DCLK1,PTGDR2,PFKFB3,DUSP26,ANLN,ST8SIA5,FLRT1,BTF3L4,MED1,SF1,MICAL2,OSBPL3,CHD5,RAB39A,USP54,CTNND2,NOS1AP,KIAA0408,ZBTB16,PHYHIP,TOMM20,LRRTM3,CADM2,CNIH3,KCNA1,OLFM3,PTPRO,SRGAP3,ARNT2,KIF2A,KLRC2,TMEM255A,DTNA,ATL1,ARHGEF10L,RPRD1A,OLIG2" MicroRNA hsa-miR-130b:mirSVR_highEffct hsa-miR-130b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.96E-37 2.14E-33 7.12E-36 6.53E-35 92 1401 "MAG,RABEPK,EPS8,CNTNAP3,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,GPR158,TESK2,SCN3A,FGF14,MOG,SOX6,ERICH3,USP28,MAGI3,TACC2,SYBU,API5,MIER1,BCO1,RUFY2,CCDC88A,SHANK2,CAPRIN2,MTR,SNAP25,USP33,SON,MYT1L,SOX5,B4GALNT1,TTLL9,SPART,CLASP2,STOX1,SMOC1,ERBIN,NEUROD1,GLS,LUZP2,CAMTA1,CAMSAP2,UNC5D,PRUNE2,SYT6,GRIA4,OMG,LINC00839,TNFRSF1B,TNS1,TPM4,PDE1C,PDE3B,ANO5,ZFYVE9,NEGR1,CCSER2,FADS2,ST8SIA5,BTF3L4,ACBD5,POU3F2,CRLS1,PPP3CB,CHD5,PKN2,USP54,ARHGEF4,NRSN1,PSD,PLPPR1,PMEPA1,PTHLH,LRP8,CEP170,CSDE1,PCDH15,CAB39L,RAB5B,PID1,ATG16L1,C12orf4,ABCC9,RET,SLC39A12,RPRD1A,VWA5A,ARHGAP12" MicroRNA hsa-miR-891b:mirSVR_lowEffct hsa-miR-891b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.78E-37 2.59E-33 8.57E-36 7.87E-35 96 1533 "ACLY,LGR4,ACTN2,ADGRV1,ATAT1,WLS,MDM4,GALNT13,ADD3,SLC44A5,LRRTM4,KIAA1109,LRRC7,SEMA6A,BCAR3,UNC79,MOBP,ARHGAP5,SCG3,SLCO1A2,DLL3,TMEM108,EIF4G3,PALLD,USP33,GAD2,ENKUR,KIF1B,COLGALT2,ERBIN,NEUROD1,NFIA,ZNF638,LUZP2,NODAL,UNC5D,BTRC,CACNA1A,NEU4,ZEB1,TCF12,VSTM2A,GRID1,TMEM257,ZFP91,PAX6,PADI2,TNS1,MAGI1,PDE2A,ZMYND8,CA14,MS4A7,GDAP1L1,CADM1,DNAJC12,MEAF6,SPATA6,SF1,RNF14,CRLS1,SNCAIP,RBPJ,RIMS3,DPYSL5,TOMM20,PLPPR5,SYNC,SIRPA,PTCH1,ITGAV,PRDM2,HP1BP3,CEP170,CSDE1,KCNA4,KCNK1,PCDH15,KCNMA1,SNX27,DLG2,SLC25A48,DNM2,FAM66C,DSCAM,FAM13C,RTN4,ZYG11B,JMJD1C,RGS7,PIANP,RBM12,VWA5A,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-376c:mirSVR_highEffct hsa-miR-376c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.01E-37 2.71E-33 8.95E-36 8.21E-35 93 1437 "PRR5L,CDHR1,TMEM74,LGR4,MEG3,FAM43B,GALNT13,SLC44A5,TESK2,LRRC7,FGF14,ELMOD1,ANK2,CNIH2,NTNG1,MSR1,PKNOX2,DACH2,SPHKAP,ASPH,SORCS3,SMARCE1,RCOR3,SNCB,PALLD,KIF21B,CAB39,SALL3,KIF1B,NCAM1,ERBIN,NEUROD1,SLCO1C1,GLS,SYT4,DDHD2,ADGRL3,GPM6A,GPM6B,CACNA1E,CACNB2,PTBP2,NUDT21,VXN,GRIA2,GRIA4,GRM3,OPCML,TGFBR3,MFSD2A,INA,LGI1,PDE3B,PIRT,ZMYND8,HNRNPK,PIK3CD,ST8SIA5,PMP2,P2RY12,NXPH1,MFSD4A,ETNPPL,PPP3CB,FEZ1,MICAL2,FMN2,PKN2,NRSN1,TOX,SYTL2,LRRTM3,LRP8,BLOC1S6,ZC3H11A,OCIAD1,C1orf109,RABGAP1L,CCDC3,KCNK1,DLG2,OLIG1,TMEM255A,GNE,FAM13C,DTNA,ABCC9,SLC6A15,JMJD1C,ZNF248,SFXN5,RAVER2,EN2" MicroRNA hsa-miR-1271:mirSVR_lowEffct hsa-miR-1271:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.37E-37 2.91E-33 9.57E-36 8.78E-35 98 1601 "EPS8,SYT9,MDM4,SLC25A25,AMER2,SLC44A5,LRRTM4,SEMA6A,FGR,SELL,ANK3,ANXA7,PKP4,APC,NTNG1,SLITRK3,ZNF365,SLC8A3,MT3,CCDC88A,SLC14A1,CGREF1,MTR,SORCS3,ATP1A2,PALLD,B3GALT2,NPAS3,NCAM1,CLASP2,STOX1,NELL1,NEUROD1,LUZP2,CAMTA1,MYRF,CDK5R2,MMD2,ADGRL3,ANO4,PRUNE2,ATF7,PRLHR,TCF12,OLR1,MFSD2A,INA,ZDHHC22,PAH,TNR,PCDH8,PCDH9,ARHGAP19,TPD52,PRMT8,HMGB1,CADM1,NRXN1,CCSER2,P2RY12,MICAL2,ATRNL1,RBPJ,PRKAB2,FMN2,NRSN1,MASP1,TOX,PHYHIP,PLPPR5,PMEPA1,BDNF-AS,PTHLH,CADM2,ELMO1,PRDM2,CEP170,PTPRZ1,KCNK2,KCNMA1,KCNN3,KIF2A,HS3ST4,SLC25A48,SLC17A6,RALGDS,ATG16L1,C12orf4,DTNA,RTN4,RET,RFX4,ARHGEF10L,ZNF248,RNF220,ABI2,OLIG2,EPB41L2" MicroRNA hsa-miR-506-3p:TargetScan hsa-miR-506-3p TargetScan 5.53E-37 3.00E-33 9.79E-36 8.98E-35 77 961 "ASIC1,RTN3,EYA1,GALNT13,RYR1,AMER2,NLGN4X,SCN4B,LRRC7,CDC42BPA,ANK1,ANXA7,JAKMIP3,RUFY2,MSRA,CCDC88A,CADPS,PALLD,KIF21B,AHCYL1,NEK6,DNER,RAP1GAP2,NFASC,C11orf87,PHLDB1,NEUROD1,NFIA,ARHGEF7,RHBDL3,MYRF,MMD2,GPM6B,CACNB2,PTBP2,GRIA2,GRID1,RFFL,P2RX7,KCNK10,PCDH8,PDE2A,PDE3B,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,PRRX1,OSBPL3,PLD5,ARHGEF4,MAPK10,PROX1,KIAA0408,DPYSL5,PMEPA1,CADM2,CSDE1,MAGI2,BLOC1S6,OLFM3,PTPRD,KCNH1,KCNK2,NAV2,KIF2A,PID1,RALGDS,DTNA,RFX4,FAM135B,PHC2,SEC61A2,CBLN2,RAVER2,EN2" MicroRNA hsa-miR-124-3p.2:TargetScan hsa-miR-124-3p.2 TargetScan 5.53E-37 3.00E-33 9.79E-36 8.98E-35 77 961 "ASIC1,RTN3,EYA1,GALNT13,RYR1,AMER2,NLGN4X,SCN4B,LRRC7,CDC42BPA,ANK1,ANXA7,JAKMIP3,RUFY2,MSRA,CCDC88A,CADPS,PALLD,KIF21B,AHCYL1,NEK6,DNER,RAP1GAP2,NFASC,C11orf87,PHLDB1,NEUROD1,NFIA,ARHGEF7,RHBDL3,MYRF,MMD2,GPM6B,CACNB2,PTBP2,GRIA2,GRID1,RFFL,P2RX7,KCNK10,PCDH8,PDE2A,PDE3B,JAM2,HEPACAM,CADM1,NEGR1,CNTN1,PRRX1,OSBPL3,PLD5,ARHGEF4,MAPK10,PROX1,KIAA0408,DPYSL5,PMEPA1,CADM2,CSDE1,MAGI2,BLOC1S6,OLFM3,PTPRD,KCNH1,KCNK2,NAV2,KIF2A,PID1,RALGDS,DTNA,RFX4,FAM135B,PHC2,SEC61A2,CBLN2,RAVER2,EN2" MicroRNA hsa-miR-519d:mirSVR_highEffct hsa-miR-519d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.91E-37 3.20E-33 1.04E-35 9.56E-35 93 1440 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,SCN3A,MOG,USP28,MAGI3,SLITRK3,TACC2,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASTN1,ATP1A2,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,SPART,LMO3,SMOC1,ERBIN,NELL1,RGL1,ADHFE1,DCLK2,CAMTA1,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,BEST3,CHGA,JAM2,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,ACBD5,CNRIP1,CRLS1,PPP3CB,FEZ2,CHD5,PRKACB,DOCK7,PKN2,NRSN1,PSD,ANKS1B,SIRPA,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,ZC3H11A,OLFM3,PTPRD,PLPPR4,PTPRO,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,SFXN5,ARHGAP12,RAVER2,TMEM100,UEVLD" MicroRNA hsa-miR-204:mirSVR_highEffct hsa-miR-204:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.95E-37 3.22E-33 1.05E-35 9.60E-35 98 1603 "DPF1,MAG,RABEPK,TTYH1,SDE2,LOC100128239,ZFYVE27,CSMD2,ARID1A,KLHL32,SLITRK1,RXRG,GALNT13,ADD3,WAC,CDC7,TMEM156,AMER2,SLC44A5,LRRTM4,KIAA1109,SEMA6A,ELMOD1,SELL,ERICH3,ASRGL1,SGIP1,USP28,USP16,YPEL4,SLC8A3,NSG2,SORCS3,SMARCE1,RCOR3,B3GAT1,ATM,MYT1L,ZCCHC24,AHCYL1,ARPP21,NEK6,TTLL9,SMOC1,ERBIN,FGF17,RGL1,GANAB,ZNF638,CAMTA1,CACNA1E,LRIT2,CACNB2,ZEB1,TCF12,SYT6,GRIA2,GRIA4,TIE1,ZFP91,CDC42,PCDH9,LGI1,TPM3,PDE4B,ZMYND8,BEST3,HMGB1,ANO5,CASC2,MS4A7,OPALIN,SLC25A27,PRRX1,SLC36A4,POU3F2,RNF14,FEZ1,DZIP3,NRSN1,TOX,SIRPA,PRDM2,OLFM3,OCIAD1,PTPRD,PTPRE,PLPPR4,C1orf109,RABGAP1L,KCNK2,PID1,TMEM255A,DNM2,DTNA,SEC61A2,ELAVL3,UEVLD" MicroRNA hsa-miR-182-5p:TargetScan hsa-miR-182-5p TargetScan 6.38E-37 3.46E-33 1.12E-35 1.03E-34 77 963 "ACER3,RIMKLA,ADCY2,ADD3,GRAMD1B,FOXRED2,GPR158,SCN3A,LRRC7,FGF14,FHL1,PDZD4,CDC42BPA,ANK3,APBA2,NTNG1,RPH3A,CCDC88A,NSG2,ASTN1,PHYHIPL,PALLD,GABBR1,MYT1L,GAD2,AHCYL1,B4GALNT1,NFASC,PHLDB1,FAM168A,NKX2-2,CAMSAP2,PRUNE2,NUDT21,GRIA1,GRID1,GRIK3,GRIK4,GUCY1A2,KCNK10,PAX6,REPS2,PC,PCDH8,LGI1,MAGI1,PIRT,CADM1,ANLN,NMT2,CNTN1,PRRX1,FAT3,MED1,PRKACB,PKN2,NRSN1,KIAA0513,RIMS3,CA10,JAKMIP2,CADM2,ELMO1,KCNA2,CDH20,AK5,KCNN3,CALN1,RALGDS,ATG16L1,DSCAM,GNE,RTN4,L1CAM,JMJD1C,RAVER2,ELAVL4" MicroRNA hsa-miR-586:PITA hsa-miR-586:PITA_TOP PITA 6.40E-37 3.47E-33 1.12E-35 1.03E-34 60 539 "LDLRAD3,CSMD3,KLHL32,RTN1,AMER2,GPR158,SCN3A,SFPQ,CDC42BPA,ANK3,GPAM,TACC2,PKNOX2,CCDC88A,SORCS3,FYN,SOX1,ERBIN,NEUROD1,SYT4,CAMTA1,ADGRL3,GPM6A,TCF12,CAMK2G,TLL2,TMEM257,REPS2,TNS1,RBFOX2,LGI1,TPM3,ZNF384,PDE4B,SERPINE2,CADM1,NEGR1,NSD2,PPP3CB,ATRNL1,IGSF1,CTNND2,RIMS3,DPYSL5,CA10,KCNA1,KCNA4,KCNK1,DLG2,DLG3,HS3ST4,PID1,SLC17A6,GOPC,RTN4,BSDC1,SLC6A15,RBM12,RAVER2,SLC4A10" MicroRNA hsa-miR-657:mirSVR_lowEffct hsa-miR-657:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.55E-37 3.55E-33 1.14E-35 1.05E-34 94 1474 "SERPINA3,RIMKLA,MAPT,CDHR1,MBP,LGR4,FAM43B,ECSIT,LDLRAD3,ARID1A,WLS,KLHL32,WAC,SORCS1,ADORA3,SCN3A,LINC00461,SEMA6A,MOBP,SLITRK3,CACHD1,SHANK2,ASCL1,CSPG5,LGI3,ASPH,MTR,SORCS3,ASTN1,ATP1A2,CAB39,KIF1B,NDUFA5,ARHGEF7,ZNF638,NHLH1,SEMA4A,CAMTA1,WWC1,PRUNE2,TCF12,PTBP2,CAMK2A,VSTM2A,GRIA1,GRIA2,RFFL,TMEM25,CDK11B,PCDH8,CDH8,LGI1,MAGI1,PDE3B,HAPLN2,PFKFB3,NRXN1,FTO,VAV2,PLXNB3,SLC25A27,BEST1,RGS6,FEZ1,MICAL2,OSBPL3,CHD5,NCAN,PRKACB,DOCK7,FMN2,PUM1,ECE2,SPIRE1,ZNF385B,CA10,BDNF-AS,CADM2,KCNA4,KCNA6,PTPRO,SRGAP3,RABGAP1L,SNX27,WIPF2,TMEM255A,GOPC,GNE,DTNA,RTN4,L1CAM,ZNF248,EPB41,SEZ6" MicroRNA hsa-miR-128-3p:TargetScan hsa-miR-128-3p TargetScan 6.71E-37 3.63E-33 1.16E-35 1.07E-34 74 882 "EYA1,LDLRAD3,MDM4,F3,ADCY2,AMER2,KIAA1109,FGF14,ANK2,PPM1E,APBA2,MAGI3,GPAM,CCDC88A,PDE8B,RCOR3,ALDH4A1,MEGF11,SCN3B,ILDR2,ARPP21,NEK6,NPAS3,NFASC,NCAM1,C11orf87,COLGALT2,NFIA,CNTN2,CACNA1A,DIRAS1,PTBP2,CECR2,BRSK2,GRIA1,GRIK3,PTPN5,KCNK10,PAX6,PCDH9,PDE3B,PRMT8,DLGAP3,CADM1,KIAA1549L,NRXN1,CABP1,MED1,NCAN,MAPK10,RIMS3,DPYSL5,CA10,ELMO1,KCNA1,KCNA4,KCNA6,KCND3,KCNK2,NAV2,KCNN3,DLG2,CALN1,DTNA,RET,JMJD1C,PHC2,GPR61,ARHGAP12,EN2,EPB41,EPB41L1,EPB41L2,RCAN2" MicroRNA hsa-miR-4262:mirSVR_highEffct hsa-miR-4262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.18E-37 3.89E-33 1.24E-35 1.14E-34 104 1810 "ACER3,CNTNAP3,ACTN2,CLIP1,SLITRK1,ERMN,AGT,KIAA1109,CDC42BPA,PPFIA1,ITSN1,DOCK10,SESN3,MAGI3,API5,MADD,MSR1,PKNOX2,CCDC88A,SLCO1A2,CAPRIN2,ASPH,SMARCE1,SNAP25,ATM,PALLD,USP33,MYBPC1,CAB39,GAD2,KIF1B,DNER,NPAS3,LMO3,C11orf87,GPR162,SEPT3,GLS,PCDH11X,GNAS,CAMTA1,CAMSAP2,PSRC1,ADGRL3,ANO4,CACNB2,TCF7L2,PTBP2,NUDT21,CAMK2G,CECR2,TMEM151B,GRIA2,GRIA4,GRIK2,GRIK3,GPR88,LEFTY2,CDH8,PDE3B,CASC2,NRXN1,NEGR1,NMT2,CNTN1,MEAF6,SLC25A27,FAT3,SF1,PPP2R5C,PPP3CB,FEZ1,OSBPL3,ATRNL1,VCAN,DOCK7,PUM1,PROX1,TOX,SPIRE1,PLPPR5,SYNC,BDNF-AS,PTHLH,BLOC1S6,OCIAD1,C1orf109,KCNJ10,ARNT2,PCDH15,KCNMA1,DLG2,PARP11,ABI1,GOPC,PAK5,ZNF248,TTLL7,LMO1,ARHGAP12,SLC4A10,ELAVL4,EN2,RPE65" MicroRNA hsa-miR-4261:mirSVR_highEffct hsa-miR-4261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.95E-37 4.30E-33 1.37E-35 1.25E-34 99 1642 "SDE2,ABAT,PRR5L,ACTN2,MEG3,MDM4,KCNIP2,CSMD3,ADAR,RXRG,WAC,SORCS1,TMEM156,SLC44A5,LRRTM4,LINC00461,UNC79,MOBP,ERICH3,ANK2,ITSN1,MAGI3,ZCCHC17,CACHD1,SYBU,SHTN1,SLC2A5,NSG2,SPHKAP,CAPRIN2,ASPH,SORCS3,PHYHIPL,B3GALT2,JPH4,EMC1,FXYD6,NCAM1,CLASP2,NELL1,RGL1,ADHFE1,NEUROD1,GLS,VAMP1,UNC5D,MMD2,PSRC1,PRUNE2,DDR1,TCF7L2,ZEB1,EML4,VXN,BRSK2,AKNA,GRIA2,GRIK2,PTPN5,MFSD2A,MAGI1,PRMT8,SCRG1,HPSE2,HERC2P3,JAM2,GDAP1L1,NEGR1,TJP2,CNTN1,CNRIP1,CP,CRMP1,CRLS1,SNCAIP,PPP3CB,CSF3R,PRKACB,DZIP3,NRSN1,PLPPR5,JAKMIP2,CEP170,MAGI2,STMN4,SRGAP3,KCNMA1,NAV2,OLIG1,GOPC,RASGRF1,ABCC9,FAM135B,INSYN2,SLC39A12,RPRD1A,LMO1,RAVER2,SEZ6" MicroRNA hsa-miR-222*:mirSVR_lowEffct hsa-miR-222*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.95E-37 4.30E-33 1.37E-35 1.25E-34 99 1642 "TMEM74,MBP,KLHL32,RTN1,SORCS1,AMER2,CHST15,TOMM40L,GPR158,SCN3A,FGF1,FHL1,GOLGA7B,ELMOD1,SOX6,PPFIA1,SH3GL2,SESN3,APC,NTNG1,MAGI3,CCDC80,TACC2,LRRC4C,DACH2,SPHKAP,DLL3,SMARCE1,KBTBD12,B3GAT1,ATM,SNCB,B3GALT2,GAD2,TTLL9,NPAS3,C11orf87,SMOC1,RGL1,SLCO1C1,NFIA,ARHGEF7,UNC5D,ANO4,GPM6B,CACNA1E,ZEB1,EML4,GRIA4,GRM3,SHISA7,OPCML,CRB1,TJP1,HPS5,LGI1,TPM3,MAGI1,PDE1C,PDE3B,PDE4B,BEST3,ANO5,PFKFB3,CASC2,CAMKV,CPT1C,CCSER2,CNRIP1,CHD1L,PPP3CB,RBPJ,IGSF1,MASP1,BRINP3,SPIRE1,DNAJC6,CA10,PTHLH,PRDM2,CSDE1,AK5,KCNJ10,PCDH15,TMEM255A,SLC17A6,FAM57B,DSCAM,GNE,DTNA,RTN4,ZYG11B,JMJD1C,ATL1,SH3GLB1,RPRD1A,GPR61,ARHGAP12,BAALC" MicroRNA hsa-miR-29b-1*:mirSVR_highEffct hsa-miR-29b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.60E-37 4.66E-33 1.47E-35 1.35E-34 101 1711 "CNTNAP3,SYT9,LGR4,RTN3,MEG3,DSCAML1,ADD3,SCN3A,LINC00461,UNC79,MOBP,USP28,ITSN1,PKP4,GPAM,API5,SHTN1,PAAF1,MIER1,SFMBT2,ARHGAP5,SHANK2,SCMH1,SCG3,SPHKAP,GABBR1,SCN3B,CAB39,NEK6,STOX1,SMOC1,NEUROD1,AJAP1,DCLK2,GNAS,UNC5D,WWC1,ATF7,TCF7L2,TCF12,EML4,CECR2,TMEM151B,VXN,SYT6,GRIA2,GRIA4,GPR88,SPX,CDH10,LGI1,TPM3,PCSK2,MAGI1,ZNF384,PRMT8,PDYN,CADM1,NEGR1,ST8SIA5,FAM181B,SLC25A27,BTF3L4,PMS2,PRRX1,CNRIP1,SNCAIP,TENM4,FEZ2,FMN2,NRSN1,MAPK10,PUM1,ZBTB16,SPIRE1,LRRTM3,PRTFDC1,HP1BP3,BLOC1S6,OLFM3,OCIAD1,KCNC1,AK5,KCNK1,KCNMA1,KCNN3,KIF2A,HS3ST4,PID1,TMEM255A,RAD52,RASGRF1,PAK5,ZYG11B,RET,ATL1,RNF220,CBLN2,ROM1,RPE65,RCAN2" MicroRNA hsa-miR-1270:mirSVR_lowEffct hsa-miR-1270:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.68E-37 4.70E-33 1.48E-35 1.36E-34 104 1814 "SERPINA3,MAP6,DUSP27,MRVI1,WLS,MDM4,CHST15,SCN4B,LINC00461,SEMA6A,MOBP,MOG,SOX6,SORBS1,CACHD1,JAKMIP3,SHTN1,SFMBT2,ARHGAP5,SLC8A3,GPR153,NAXD,ASPH,ASTN1,RCOR3,ATM,EIF4G3,ATP2B2,SCN3B,CAB39,ADAM15,KIF1B,SPART,NCAM1,C11orf87,ALDH1L1,NDUFA5,INKA2,RGL1,NEUROD1,ACSBG1,GLS,CDK5R2,BTRC,WWC1,KLHL4,PRUNE2,LRIT2,CACNB2,NUDT21,TMEM151B,VXN,GRID1,TMEM257,KCNK10,DAAM2,MAEL,REPS2,IGSF21,TPM4,LINC01102,FNDC5,PFKFB3,CHRM1,TMEFF2,HEPACAM,NLGN3,CCSER2,TJP2,SF1,PTPA,PPP2R5C,SNCAIP,CSF3R,ATRNL1,FMN2,CTNND1,KIAA0408,MASP1,JAKMIP2,CEP170,CSDE1,BLOC1S6,CDH20,OCIAD1,SMG7,PLPPR4,NTM,KCNJ9,CCDC3,ARNT2,DLG2,RAB5B,TMEM255A,FAM66C,RALGDS,NUP214,FAM135B,INSYN2,ARHGEF10L,PHC2,VANGL2,RPRD1A,UEVLD" MicroRNA hsa-miR-3188:mirSVR_lowEffct hsa-miR-3188:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.97E-37 4.85E-33 1.53E-35 1.40E-34 100 1678 "TTYH1,WLS,CSMD3,KLHL32,FOXRED2,TESK2,BBOX1,USP28,DGKD,SHTN1,ZNF365,KIAA1614,SLC1A7,CADPS,NAXD,ASPH,KBTBD12,IGSF9B,ATP2B2,MEGF11,TNIK,SOX5,KIF21B,SALL3,TTLL9,FXYD6,NPAS3,NFASC,ALDH1L1,GFRA1,INKA2,HEPN1,SYT4,POPDC3,GNAS,PRUNE2,GPM6B,PCDHGA3,VXN,GRIA1,OMG,CRB1,TLL2,MAEL,TNFRSF1B,TNS1,RBFOX2,HRH3,ZNF384,PDE3B,PDYN,FNDC5,CA14,PFKFB3,CHRM1,PLEKHB1,CASC2,CAMKV,NEGR1,PIK3CD,CPT1C,FAM181B,VAV2,CABP1,SPATA6,FAT3,NXPH1,CP,CHD1L,PLPP4,PRKCZ,CTNND1,MAPK10,MASP1,GON4L,SPIRE1,ITGAV,CNIH3,PRDM2,HP1BP3,SHD,SV2A,SRGAP3,KCNJ10,KCNJ11,ARNT2,KCNMA1,KCNN3,NKAIN1,PLEKHB2,GOPC,DTNA,CAMK1G,USH1C,INSYN2,PIANP,FGFBP3,EPB41L2,RCAN2,BAALC" MicroRNA hsa-miR-490-5p:mirSVR_lowEffct hsa-miR-490-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.99E-37 4.87E-33 1.53E-35 1.40E-34 96 1545 "EPS8,SRARP,MRVI1,F3,DSCAML1,WAC,SORCS1,ADORA1,NLGN4X,LRRC7,SEMA6A,BCAR3,HPCAL4,MOBP,SOX6,ERICH3,SGIP1,ANK1,PPM1E,ZNF365,LRRC55,SHANK2,DACH2,SPHKAP,ASPH,BRINP2,ASTN1,SMARCE1,TMEM108,SNAP25,TMEM151A,JPH4,EMC1,FXYD6,SPART,NFASC,NCAM1,BCL2L2,ALDH1L1,SMOC1,GFAP,NEUROD1,GNAS,ADGRL3,PRUNE2,ACSL6,TCF12,PTBP2,VXN,SYT6,BRSK2,RFFL,CRB1,GUCY1A2,KCNK10,CDC42,PADI2,PCDH9,PTGDR2,LGI1,PCSK2,PDE2A,PIRT,LINC01102,HEPACAM,ZFYVE9,DNAJC12,MFSD4A,PPP3CB,RGS6,RBPJ,PRKACB,DZIP3,CTNND2,MAPK8,NOS1AP,GON4L,MAGI2,KCNA1,SMG7,KCNC1,PTPRZ1,SRGAP3,RABGAP1L,SNX27,OLIG1,DNM2,DPP6,SUSD4,DBX2,ABCC9,CRTAC1,RFX4,ATL1,SYT15,EPB41L1" MicroRNA hsa-miR-1243:mirSVR_lowEffct hsa-miR-1243:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.43E-37 5.11E-33 1.60E-35 1.46E-34 98 1612 "SYT9,RTN3,LDLRAD3,SLC25A25,CSMD3,KLHL32,GALNT13,PNMA8B,SORCS1,AMER2,NLGN4X,SEMA6A,ELMOD1,SFPQ,ERICH3,SGIP1,PPFIA1,ITSN1,PPM1E,DOCK10,NTNG1,ARHGAP5,SLC8A3,SHANK2,SLC14A1,DACH2,SLCO1A2,ASPH,BRINP2,SORCS3,SMARCE1,ATM,FYN,SOX5,C11orf87,COLGALT2,STOX1,ARHGEF7,ZNF638,NHLH1,CAMTA1,GNG4,ANO4,GPM6A,VXN,SYT6,GRIA4,OPCML,PAH,REPS2,IGSF21,ARHGAP19,LGI1,PDE3B,ACOT7,ANO5,CHI3L2,CASC2,TJP2,DNAJC12,BEST1,P2RY12,CNRIP1,OSBPL3,FMN2,KIAA0408,ZBTB16,PSMD13,CA10,BDNF-AS,CADM2,ELMO1,CEP170,CSDE1,OCIAD1,PTPRD,KCNC1,SRGAP3,NTM,KCNK1,DLG2,CAB39L,HS3ST4,OLIG1,KLRC2,TMEM255A,FAM66C,GOPC,DSCAM,BSDC1,ABCC9,JMJD1C,ZNF248,SYT15,RNF220,ARHGAP12,EN2,BAALC" MicroRNA hsa-miR-421:mirSVR_highEffct hsa-miR-421:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.51E-37 5.15E-33 1.60E-35 1.47E-34 91 1385 "EPS8,SDE2,ACER3,SYT9,LGR4,ACTN2,RTKN,KCNIP2,ADD3,CHST15,TESK2,AGT,FGF14,FHL1,ELMOD1,PPFIA1,ITSN1,MAGI3,SHTN1,MIER1,TAGLN3,ASPH,SORCS3,SMARCE1,SNAP25,ATM,DKK3,MYBPC1,WDTC1,MYT1L,B3GALT2,SOX5,ARPP21,GART,NCAM1,C11orf87,COLGALT2,ERBIN,NEUROD1,ZNF638,CAMTA1,ADGRL3,KLHL4,PRUNE2,ZEB1,PTBP2,GRIA4,GRIK4,FBXL16,PAH,ARHGAP19,LGI1,PRMT8,PDE4B,CA14,ANO5,PFKFB3,CHI3L2,CASC2,CADM1,CNTN1,NSD2,POU3F4,SF1,CRLS1,MICAL2,PLD5,SPIRE1,JAKMIP2,CADM2,BLOC1S6,PTPRD,PTPRO,PTPRZ1,SV2A,RABGAP1L,KCNJ10,DLG2,DPP6,GOPC,DSCAM,FAM13C,ZYG11B,RFX4,PHC2,ZNF248,SYT15,SEC61A2,ARHGAP12,SLC4A10,RCAN2" MicroRNA hsa-miR-130a:mirSVR_highEffct hsa-miR-130a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.51E-37 5.15E-33 1.60E-35 1.47E-34 91 1385 "MAG,EPS8,CNTNAP3,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,GPR158,TESK2,SCN3A,FGF14,MOG,ERICH3,USP28,DOCK10,MAGI3,CCDC80,SLITRK3,TACC2,SYBU,API5,AQP4,MIER1,BCO1,RUFY2,CCDC88A,SHANK2,NAXD,CAPRIN2,MTR,SNAP25,USP33,MYT1L,SOX5,B4GALNT1,TTLL9,SPART,NDUFA5,STOX1,SMOC1,ERBIN,NEUROD1,GLS,CAMTA1,CAMSAP2,PRUNE2,SYT6,GPR88,OMG,LINC00839,TNFRSF1B,TNS1,PDE1C,PDE3B,TLX1,DUSP26,ZFYVE9,NEGR1,CCSER2,ST8SIA5,CCDC136,BTF3L4,ACBD5,POU3F2,CRLS1,CHD5,PKN2,ARHGEF4,NRSN1,PSD,PLPPR1,PMEPA1,PTHLH,LRP8,CEP170,CSDE1,PCDH15,KCNN3,CAB39L,RAB5B,PID1,ATG16L1,RTN4,ABCC9,RET,SLC39A12,RPRD1A,VWA5A,ARHGAP12" MicroRNA hsa-miR-3142:mirSVR_lowEffct hsa-miR-3142:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.76E-37 5.29E-33 1.64E-35 1.50E-34 90 1354 "ABAT,ASIC1,SYT9,LGR4,ACTN2,MEG3,MDM4,ADCY2,SORCS1,FCGR1A,FCGR1B,GPR158,MOBP,SOX6,USP28,ITSN1,SLC1A7,ARFGAP2,SLC8A3,ASPH,KBTBD12,TMEM108,EIF4G3,FYN,ATP2B2,JPH4,B4GALNT1,C11orf87,GFAP,FGF17,HEPN1,GJB1,GLS,DCLK2,SEMA4A,UNC5D,NUDT21,PCDHGA3,CECR2,SYT6,NUMA1,AKNA,GRID1,RFFL,OMG,CCKBR,P2RX7,PCSK2,PRMT8,FNDC5,PFKFB3,ASIC3,MS4A7,TMEFF2,PLXNB3,SLC25A27,BEST1,SPATA6,NXPH1,CNRIP1,MFSD4A,SNCAIP,CSF3R,FEZ1,FMN2,CMTM5,ECE2,MASP1,DPYSL5,PMEPA1,PTHLH,CEP170,KCNA1,CDH20,KCNJ11,KCNK1,RAB3IL1,FAM66C,ATN1,PAK5,CRTAC1,CAMK1G,RET,RGS10,INSYN2,ARHGEF10L,SSPN,SIDT2,ELAVL4,ROM1" MicroRNA hsa-miR-373:mirSVR_highEffct hsa-miR-373:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-36 5.46E-33 1.69E-35 1.55E-34 94 1482 "EPS8,SYT9,LGR4,MDM4,FABP7,AMER2,GPR158,SCN3A,ANK2,MAGI3,SLITRK3,TACC2,API5,SHTN1,CLSTN1,USP16,SLC1A6,SLC14A1,ASPH,RCOR3,MYT1L,TNIK,ENKUR,ARPP21,LMO3,CLASP2,DCAF5,RGL1,NEUROD1,SLCO1C1,ARHGEF7,ZNF638,CAMTA1,CAMSAP2,UNC5D,GPM6A,CACNA1E,TCF7L2,ZEB1,CECR2,NUMA1,GRIA1,RFFL,CRB1,TMEM25,LEFTY2,TGFBR3,AIFM1,HPS5,TNS1,C1orf94,PCDH9,PCSK2,MAGI1,PRMT8,BEST3,NRXN1,FAM181B,PRRX1,SPATA6,ACBD5,CNRIP1,PPP3CB,KCNT2,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,ITGAV,PTHLH,CADM2,PRTFDC1,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRD,RABGAP1L,PCDH15,KCNMA1,HS3ST4,TMEM255A,SLC17A6,FAM13C,DTNA,PAK5,ABCC9,SLC6A15,ZYG11B,TMEM100" MicroRNA hsa-miR-93:mirSVR_highEffct hsa-miR-93:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.04E-36 5.65E-33 1.74E-35 1.60E-34 98 1614 "MAP6,CNTNAP3,MDM4,F3,WAC,SORCS1,AMER2,HOGA1,SCN3A,MOG,SOX6,USP28,MAGI3,CCDC80,SLITRK3,SYBU,SHTN1,USP16,AQP4,RUFY2,MSR1,LRRC55,CCDC88A,CAPRIN2,ASTN1,ATM,ATP1A2,GABBR1,USP33,MYT1L,B3GALT2,B4GALNT1,ARPP21,NPAS3,SPART,LMO3,SMOC1,ERBIN,RGL1,ADHFE1,DCLK2,CAMTA1,LINC00839,TMEM25,ZFP91,HPS5,TNS1,PDE3B,PRMT8,BEST3,CHGA,MS4A7,HNRNPK,ZFYVE9,UBTF,CCSER2,SLC25A27,PRRX1,ACBD5,CNRIP1,CRLS1,PPP3CB,FEZ2,CHD5,PRKACB,DOCK7,PKN2,NRSN1,PSD,ANKS1B,SIRPA,ITGAV,CA10,PTHLH,CADM2,HP1BP3,RGMA,CEP170,CSDE1,OLFM3,PTPRD,KCNJ10,PCDH15,KCNMA1,OLIG1,RAB5B,ATG16L1,FAM13C,PAK5,ABCC9,ZYG11B,SFXN5,EFNA3,ARHGAP12,RAVER2,SLC4A10,TMEM100,UEVLD" MicroRNA hsa-miR-4268:mirSVR_lowEffct hsa-miR-4268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-36 6.56E-33 2.01E-35 1.85E-34 101 1718 "MAG,TTYH1,SDE2,ABAT,ATAT1,ARID1A,GRAMD1B,ADORA1,TESK2,PPFIA1,ITSN1,DGKZ,NLGN1,PAAF1,RPH3A,LRRC55,SLC8A3,CCDC88A,NSG2,DACH2,CGREF1,SCG3,MTR,ADGRA1,NRG3,ATP1A3,USP33,MYT1L,CADM3,SOX10,ZSWIM8,ADAM15,KIF1B,SPART,BCL2L2,ALDH1L1,PHLDB1,RND1,ZNF638,SEMA4A,MYRF,PSRC1,PRUNE2,SYT6,NUMA1,BRSK2,GRIA1,RFFL,LEFTY2,MFSD2A,AIFM1,PAH,CDH10,RBFOX2,TPM3,PDE1A,TMPRSS5,PFKFB3,ASIC3,CASC2,TLX1,DUSP26,GDAP1L1,KIAA1549L,NRXN2,CPT1C,CNTN1,CABP1,SLC25A27,BTF3L4,NSD2,MFSD4A,CHD1L,CRMP1,PTPA,PPP3CB,NKAIN4,PLD5,PRKCZ,CTNND1,NRSN1,MAPK10,ECE2,ZBTB16,WBP1L,TOMM20,PSMD13,DNAJC6,CA10,PRDM2,CSDE1,KCNC1,PTPRO,SRGAP3,KCNJ11,NKAIN1,PID1,C12orf4,NUP214,VANGL2,SEZ6" MicroRNA hsa-miR-708:mirSVR_lowEffct hsa-miR-708:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-36 6.87E-33 2.10E-35 1.93E-34 100 1685 "LDLRAD3,NDRG2,ADCY2,SLITRK1,WAC,SORCS1,TUBB4A,NLGN4X,GPR158,MOG,C1orf61,SOX6,SELL,CDC42BPA,ANK2,SH3GL2,DOCK10,NTNG1,SYBU,SLC1A7,URGCP,LRRC55,SLC8A2,SLC8A3,NSG2,TAGLN3,NAXD,ASPH,BRINP2,RCOR3,DKK3,GABBR1,MYH7,ARPP21,IDI2-AS1,ADAM15,NCAM1,CLASP2,COLGALT2,ALDH1L1,KIRREL3,NEUROD1,SEPT3,CASTOR3,ZNF638,POPDC3,ROBO3,BTRC,PRUNE2,VXN,GRIA4,GPR88,PTGDR2,TPM3,MAGI1,PDE3B,BEST3,PFKFB3,PLEKHB1,CASC2,HNRNPK,JAM2,GDAP1L1,KIAA1549L,UBTF,DNAJC12,ST8SIA5,MFSD4A,SF1,CRMP1,CRLS1,PTPA,MICAL2,ATRNL1,VCAN,PRKAB2,DOCK7,SDC3,CMTM5,PLD5,IGSF1,ECE2,NOS1AP,MASP1,PLPPR5,LRRTM3,HP1BP3,KCNA6,KCNK1,WIPF2,L1CAM,RFX4,RFX5,FAM135B,PHC2,RNF220,CACNG7,SH3GLB1,RCAN2,SEZ6" MicroRNA hsa-miR-24:mirSVR_lowEffct hsa-miR-24:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-36 7.43E-33 2.27E-35 2.08E-34 109 2000 "LOC100128239,ZFYVE27,ACER3,ACHE,PNMA8B,SORCS1,ADORA1,SNX30,HOGA1,SCN3A,ASIC4,SELL,ANK3,SORBS1,CACHD1,ST3GAL3,JAKMIP3,SLC8A2,ARFGAP1,NAXD,ASPH,B3GAT1,ADGRA1,SNCB,WDTC1,KIF21B,CADM3,SOX10,ZSWIM8,AHCYL1,B4GALNT1,ARPP21,TTLL9,ADAM15,NFASC,BCL2L2,DCAF5,SEPT3,CASTOR3,PCDH11X,MYRF,GOLGB1,TMEM136,TBX15,DDR1,PTBP2,NUDT21,CAMK2G,CECR2,TMEM151B,SYT6,AKNA,GRIA1,GRIA2,GRIN1,CYB561A3,ATP13A2,OPCML,CCKBR,LINC00839,LEFTY2,INA,TMEM9,CDK11B,PCDH9,CDH8,RBFOX2,PDE1A,PDE2A,ANO5,PFKFB3,KIAA1549L,NRXN1,NOMO2,TJP2,FLRT1,PLXNB3,C11orf49,IFFO1,ATCAY,CHD1L,MED1,PTPA,RGS6,PLCH2,WBP1L,PRDM2,COPS7A,ZC3H11A,KCNA4,OCIAD1,PTPRZ1,SV2A,RABGAP1L,DLG2,NKAIN1,RAB3IL1,RAB5B,TMEM255A,RASGRF1,PAK5,USH1C,ZNF248,PIANP,EFNA3,FGFBP3,RAVER2,SEZ6,BAALC" MicroRNA hsa-miR-4283:mirSVR_lowEffct hsa-miR-4283:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-36 8.99E-33 2.73E-35 2.51E-34 89 1332 "MAG,ZFYVE27,ASIC1,EMID1,SYNDIG1,LDLRAD3,KCNIP2,RTN1,SLITRK1,ADD3,ADORA1,TUBB4A,LCNL1,SNX32,HOGA1,SCN4B,PLA2G6,ASIC4,PDZD4,SGIP1,ITSN1,NTNG1,ST3GAL3,RPH3A,SLC1A7,PKNOX2,SLC6A9,SLC8A3,CCDC88A,NAXD,SCN3B,IDI2-AS1,ALDH1L1,NDUFA5,NCDN,ADHFE1,ACSBG1,MLC1,C1QC,GNAS,NODAL,MYRF,WWC1,DDR1,NRGN,PTBP2,NUCB1,GRIA4,GRID1,GRIN1,SPX,AIFM1,MAGI1,IGFN1,GDAP1L1,KIAA1549L,NOMO2,MFSD4A,CHD1L,PPP3CB,OSBPL3,NCAN,RIMS4,DOCK7,IGSF1,NRSN1,PUM1,HES5,ECE2,BDNF-AS,PRDM2,OCIAD1,SMG7,PTPRE,SV2A,KCNJ11,CAB39L,WIPF2,DNM2,RAP1GAP,BSDC1,RGR,VANGL2,PIANP,ABI2,CBLN2,SLC4A10,SEZ6,BAALC" MicroRNA hsa-miR-15a:mirSVR_highEffct hsa-miR-15a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.76E-36 9.51E-33 2.88E-35 2.64E-34 93 1460 "CDHR1,RTN3,SYNDIG1,EYA1,CSMD2,GALNT13,CDC7,SCN3A,DISP3,LRRC7,ELMOD1,SLC30A10,ANK2,SH3GL2,PPM1E,GPAM,NLGN1,ST3GAL3,BCAS1,MSR1,ARFGAP2,CSPG5,SLN,RCOR3,SNAP25,SON,MYBPC1,MYT1L,ARPP21,TTLL9,KIF1B,NAP1L2,NPAS3,NFASC,BCL2L2,PHLDB1,ACSBG1,SYT4,KAZN,GNAS,BTRC,ADGRL3,WWC1,CACNA1E,PTBP2,VSTM2A,OMG,TGFBR3,CDC42,PCDH9,BEST3,CADM1,PLXNB3,BTF3L4,PRRX1,NXPH1,MFSD4A,MED1,PPP2R5C,PPP3CB,FEZ2,MICAL2,RBPJ,PRKCG,PKN2,MASP1,SYTL2,ANKS1B,JAKMIP2,PTHLH,CSDE1,PTPRD,SMG7,NTM,KCNJ11,KCNK1,KCNK2,PEX5,DLG2,KIF2A,DNAH9,PID1,TMEM255A,SLC6A15,RET,RFX4,SEC61A2,SIDT2,RBM12,ARHGAP12,EN2,TMEM100,RCAN2" MicroRNA hsa-miR-1278:mirSVR_lowEffct hsa-miR-1278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.82E-36 9.83E-33 2.97E-35 2.73E-34 94 1493 "ACER3,MRVI1,CSMD2,CSMD3,SLITRK1,ADD3,SCN3A,LRRTM4,BBOX1,ELMOD1,PPFIA1,ANXA7,SESN3,NTNG1,MAGI3,CCDC80,DGKD,SHTN1,RUFY2,MSR1,MSRA,PKNOX2,SCMH1,SPHKAP,SMARCE1,C10orf105,SNAP25,MYT1L,ENKUR,B4GALNT1,NFASC,NCAM1,C11orf87,AJAP1,ARHGEF7,CASTOR3,GNAS,CAMTA1,UNC5D,CNDP1,ANO4,ACSL6,ZEB1,NUDT21,CECR2,GRIA4,ADAMTS8,CRB1,P2RX7,TIE1,TMEM9,PCDH8,PCDH9,CDH8,TPD52,PDYN,HNRNPK,TMEFF2,CADM1,KIAA1549L,NEGR1,CCSER2,TJP2,DNAJC12,SULT4A1,PPP2R5C,SNCAIP,PPP3CB,MICAL2,USP54,ARHGEF4,ECE2,KIAA0408,GON4L,TOMM20,PLPPR1,PTHLH,CEP170,KCNA4,KCNA6,PTPRE,PLPPR4,RABGAP1L,KCNK2,DLG2,WIPF2,KLRC2,FAM13C,SLC6A15,RPRD1A,SLC4A10,RPE65,RCAN2,BAALC" MicroRNA hsa-miR-4267:mirSVR_lowEffct hsa-miR-4267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-36 1.00E-32 3.01E-35 2.76E-34 105 1865 "DPF1,EPS8,LOC100128239,ZFYVE27,ASIC1,SYT9,EXTL1,MDM4,SLITRK1,GALNT13,ADD3,WAC,FCGR1A,TOMM40L,TESK2,DISP3,FGF1,C1orf61,ANK1,ZCCHC17,JAKMIP3,SHTN1,SLC1A6,MSRA,LRRC55,PKNOX2,SLC8A2,NSG2,PDE8B,GPR153,SPHKAP,CAPRIN2,ASPH,SMARCE1,TMEM151A,TNIK,NMNAT2,JPH4,ARPP21,FXYD6,NFASC,RGL1,GJB1,RND1,ARHGEF7,GLS,DCLK2,KAZN,GNAS,LILRA1,CAMK2G,CYB561A3,OPCML,MFSD2A,FBXL16,INA,KCNK10,TNS1,PDE1A,IGFN1,LINC01102,FNDC5,BEST3,NLGN3,CAMKV,FAM181B,CELF5,BEST1,PACSIN1,ATCAY,NXPH1,CP,PPP3CB,MICAL2,ATRNL1,DZIP3,CMTM5,ECE2,NOS1AP,PROX1,PSD,SPIRE1,TOMM20,LRRTM3,PTAFR,PLPPR1,BDNF-AS,CNIH3,COPS7A,SV2A,NTM,KCNJ9,KCNK1,SLC25A48,DNM2,ATG16L1,SLC25A41,SLC25A18,JMJD1C,ARHGEF10L,SIDT2,ROM1,OLIG2,EPB41,EPB41L1" MicroRNA hsa-miR-221:mirSVR_lowEffct hsa-miR-221:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-36 1.00E-32 3.01E-35 2.76E-34 95 1526 "MAP6,LGR4,RTN3,MDM4,F3,RTN1,ADD3,LRRC7,FGF14,ASIC4,BBOX1,MOBP,FOXG1,SELL,ERICH3,USP28,ITSN1,PKP4,GPAM,SLITRK3,ST8SIA1,SHTN1,PAAF1,ZNF365,RPH3A,CGREF1,SCG3,SLN,ASTN1,SMARCE1,SNAP25,SNCB,USP33,SOX1,IDI2-AS1,NCAM1,CLASP2,RGL1,AJAP1,SLCO1C1,ARHGEF7,PCDH11X,ZNF638,BTRC,ADGRL3,KLHL4,PRUNE2,ATF7,TCF7L2,NUDT21,NUMA1,CRB1,TMEM25,AIFM1,PCDH8,PCDH9,FNDC5,CASC2,TUB,HNRNPK,NRXN1,NEGR1,CCSER2,OPALIN,NSD2,CNRIP1,MFSD4A,CP,POU3F2,PPP2R5C,OSBPL3,ATRNL1,PRKAB2,DOCK7,USP54,CTNND2,NRSN1,RIMS3,ANKS1B,SPIRE1,PLPPR5,ZNF385B,PMEPA1,LRP8,CEP170,OCIAD1,C1orf109,PTPRZ1,PCDH15,KCNMA1,DLG2,PID1,ATN1,BSDC1,SLC6A15" MicroRNA hsa-miR-922:mirSVR_highEffct hsa-miR-922:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-36 1.00E-32 3.01E-35 2.76E-34 93 1461 "MAPT,CDHR1,CNTNAP3,RCSD1,ADGRV1,SLITRK1,SLC44A5,GPR158,SCN3A,LINC00461,ELMOD1,AMPH,ERICH3,ASRGL1,ANK3,SH3GL2,APBB1,GPAM,NLGN1,ST3GAL3,API5,MIER1,ARHGAP5,CCDC88A,CGREF1,CSPG5,SON,MYBPC1,WDTC1,KIF21B,CAB39,ARPP21,EMC1,SPART,NCAM1,LMO3,C11orf87,GJB1,SEPT3,ARHGEF7,GLS,PCDH11X,GNAS,CAMTA1,ADGRL3,GPM6B,CACNB2,PTBP2,EML4,SYT6,NUMA1,GRIA2,TGFBR3,CDC42,CDH10,DCLK1,PDE3B,BEST3,MS4A7,TMEFF2,CADM1,NOMO2,P2RY12,NSD2,MED1,SF1,MICAL2,DZIP3,PLD5,NRSN1,FGFR1OP2,PSD,WBP1L,SYTL2,ANKS1B,SYNC,DNAJC6,PTHLH,PRDM2,OCIAD1,PTPRD,KCND3,TMCC2,KCNK1,KCNK2,KCNMA1,CAB39L,DSCAM,GNE,BSDC1,SEC61A2,SLC39A12,EN2" MicroRNA hsa-miR-924:mirSVR_lowEffct hsa-miR-924:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-36 1.02E-32 3.04E-35 2.79E-34 101 1727 "TTYH1,SDE2,ZFYVE27,IL17D,ATAT1,ARID1A,MDM4,KCNIP2,CSMD3,F3,KLHL32,CDC7,GPR158,LRRC7,ELMOD1,MOG,CDC42BPA,PPFIA1,ITSN1,APC,NTNG1,MAGI3,CCDC80,SLITRK3,CACHD1,API5,USP16,AQP4,ARFGAP2,YPEL4,MT3,SLC14A1,TAGLN3,B3GAT1,ADGRA1,NRG3,EIF4G3,SCN3B,SON,NEK6,FXYD6,NFASC,NCAM1,C11orf87,CLASP2,GFRA1,NELL1,CAMTA1,UNC5D,TMEM136,TCF7L2,CAMK2G,VXN,SYT6,CYB561A3,MFSD2A,GUCY1A2,DAAM2,RBFOX2,SEZ6L,PDE3B,CHGA,ASIC3,TMEFF2,TLX1,HEPACAM,CADM1,CPT1C,FTO,CNTN1,PPP2R5C,KCNT2,FEZ1,ATRNL1,VCAN,RBPJ,PRKACB,PLD5,TOX,RIMS3,PRDM2,PRTFDC1,LRP8,CEP170,PTPRZ1,TMCC2,NAV2,OLIG1,WIPF2,ZYG11B,FAM135B,TTLL7,SLC39A12,RBM12,GPR61,ARHGAP12,SLC4A10,ROM1,EPB41,RCAN2,RASGRP2" MicroRNA hsa-miR-885-5p:mirSVR_lowEffct hsa-miR-885-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-36 1.17E-32 3.49E-35 3.21E-34 95 1529 "ZFYVE27,MBP,CNTNAP3,ACTN2,ARID1A,KLHL32,RTN1,SLITRK1,ADD3,CDC7,SORCS1,SLC44A5,TESK2,FGF14,FHL1,UNC79,SOX6,SELL,SFPQ,ASRGL1,ANK2,PPFIA1,PKP4,SLITRK3,NLGN1,DACH2,ASCL1,SPHKAP,DLL3,ASPH,RCOR3,MEGF11,USP33,SOX5,CAB39,NMNAT2,KIF1B,FXYD6,SLCO1C1,FAM168A,ARHGEF7,PCDH11X,DCLK2,BTRC,ADGRL3,ANO4,GPM6A,GPM6B,ATF7,ACSL6,VWC2,TCF7L2,VXN,GRIK2,ADAMTS8,OPCML,TMEM25,INA,HPS5,PCDH8,LGI1,PDE4B,HMGB1,LRTM2,CASC2,DUSP26,SULT4A1,BEST1,BTF3L4,MED1,RNF14,DOCK7,PUM1,DPYSL5,PLPPR5,DNAJC6,ITGAV,CA10,BDNF-AS,PRDM2,RGMA,CEP170,KCNA4,KCNA6,C1orf109,NTM,CALN1,DPP6,C12orf4,FAM13C,SLC6A15,SH3GLB1,ELAVL3,YY1AP1,SEZ6" MicroRNA hsa-miR-19b:PITA hsa-miR-19b:PITA_TOP PITA 2.20E-36 1.19E-32 3.53E-35 3.23E-34 68 741 "RIMKLA,ASIC1,CLIP1,RTN1,WAC,GPR158,TESK2,SCN3A,SCN4B,SOX6,CDC42BPA,ITSN1,ANXA7,DOCK10,API5,SHTN1,ARHGAP5,CCDC88A,CAPRIN2,RCOR3,ATP2B2,MYT1L,SOX5,CAB39,GAD2,SMOC1,RGL1,NEUROD1,FAM168A,CAMTA1,CAMSAP2,ZFP91,TNFRSF1B,RBFOX2,PDE1C,PFKFB3,TUB,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CRMP1,PTPA,MICAL2,CHD5,PSD,WBP1L,DPYSL5,PMEPA1,CEP170,MAGI2,KCNA4,PTPRD,SV2A,SRGAP3,KCNK2,SNX27,DLG2,RAB5B,ATG16L1,DSCAM,ZYG11B,ST8SIA3,INSYN2,SEC61A2,ARHGAP12,CBLN2" MicroRNA hsa-miR-19a:PITA hsa-miR-19a:PITA_TOP PITA 2.20E-36 1.19E-32 3.53E-35 3.23E-34 68 741 "RIMKLA,ASIC1,CLIP1,RTN1,WAC,GPR158,TESK2,SCN3A,SCN4B,SOX6,CDC42BPA,ITSN1,ANXA7,DOCK10,API5,SHTN1,ARHGAP5,CCDC88A,CAPRIN2,RCOR3,ATP2B2,MYT1L,SOX5,CAB39,GAD2,SMOC1,RGL1,NEUROD1,FAM168A,CAMTA1,CAMSAP2,ZFP91,TNFRSF1B,RBFOX2,PDE1C,PFKFB3,TUB,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CRMP1,PTPA,MICAL2,CHD5,PSD,WBP1L,DPYSL5,PMEPA1,CEP170,MAGI2,KCNA4,PTPRD,SV2A,SRGAP3,KCNK2,SNX27,DLG2,RAB5B,ATG16L1,DSCAM,ZYG11B,ST8SIA3,INSYN2,SEC61A2,ARHGAP12,CBLN2" MicroRNA hsa-miR-1183:mirSVR_highEffct hsa-miR-1183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-36 1.20E-32 3.55E-35 3.25E-34 80 1066 "MBP,CSMD3,F3,GALNT13,SLC44A5,KIAA1109,MOBP,SGIP1,CDC42BPA,ANK3,CNIH2,APC,SHTN1,MSRA,ARFGAP2,CADPS,ASPH,SMARCE1,TNIK,ARHGEF7,PCDH11X,NHLH1,PSRC1,TMEM136,ANO4,GPM6B,TCF7L2,ZEB1,CAMK2A,VXN,GRIA2,MFSD2A,TJP1,CD81,MAEL,HPS5,CDH8,CDH10,LGI1,PDE4B,BEST3,HMGB1,TMEFF2,NEGR1,ANLN,NSD2,CNRIP1,RNF14,KCNT2,FEZ2,ATRNL1,PRKACB,PKN2,NRSN1,MASP1,PLPPR5,PTAFR,PTCH1,DNAJC6,ITGAV,CA10,PMEPA1,CADM2,COPS7A,KCNA2,PTPRD,PLPPR4,PTPRZ1,NTM,KCNJ10,KCNJ11,DLG2,GOPC,SLC6A15,VANGL2,SEC61A2,RPRD1A,YY1AP1,TMEM100,EPB41L2" MicroRNA hsa-miR-555:mirSVR_lowEffct hsa-miR-555:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.23E-36 1.21E-32 3.56E-35 3.26E-34 83 1154 "SDE2,MRVI1,MDM4,KCNIP2,GALNT13,TUBB4A,SNX32,TRIM46,CNIH2,ITSN1,PPM1E,NTNG1,ST3GAL3,API5,MIER1,CCDC88A,SLCO1A2,CAPRIN2,MTR,USP33,WDTC1,TNIK,CADM3,SOX10,B4GALNT1,TTLL9,NASP,SPART,C11orf87,ALDH1L1,MLC1,ZNF638,KAZN,CAMTA1,CDK5R2,ANO4,TBX15,ZEB1,CAMK2G,SYT6,GRIA1,INA,TJP1,ZFP91,PCDH9,TPM4,MAGI1,PDE2A,PRMT8,TMEFF2,ARHGAP22,KIAA1549L,ANLN,FTO,FAM181B,CCDC136,CELF5,CHD1L,PTPA,OSBPL3,USP54,MASP1,KLK6,LRRTM3,CA10,PRDM2,OLFM3,PTPRD,KCNA6,KCNC1,PTPRZ1,RABGAP1L,KCNJ10,PCDH15,KCNN3,DNM2,SLC17A6,FAM57B,RASGRF1,SLC6A15,JMJD1C,EPB41L2,UEVLD" MicroRNA hsa-miR-433:mirSVR_lowEffct hsa-miR-433:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.25E-36 1.22E-32 3.57E-35 3.28E-34 102 1765 "PRR5L,MBP,LGR4,EYA1,WLS,ADAR,FABP7,SORCS1,FGF1,PLA2G6,LRRC7,SEMA6A,MOBP,FOXG1,SOX6,CNIH2,PPFIA1,DOCK10,CCDC80,SORBS1,ST3GAL3,BCAS1,USP16,ZNF365,SLC14A1,CADPS,CAPRIN2,SLN,BRINP2,SMARCE1,KBTBD12,NRG3,NMNAT2,ARPP21,NEK6,C11orf87,NELL1,GJB1,AJAP1,PCDH11X,CAMSAP2,BTRC,PRUNE2,ACSL6,SYT6,RFFL,ATP13A2,CRB1,NEURL1,KCNK10,CD81,PAX6,HPS5,CDC42,MAGI1,PDE1A,LINC01102,ANO5,ASIC3,CASC2,ZBED5,TMEFF2,JAM2,DUSP26,NEGR1,ANLN,PIK3CD,VAV2,PLXNB3,MEAF6,CELF5,PRRX1,SF1,CRLS1,MICAL2,OSBPL3,ATRNL1,USP54,IGSF1,KIAA0408,TOMM20,LRRTM3,CADM2,PRDM2,PTPRD,PLPPR4,KCNC1,PTPRO,SRGAP3,KCNK1,SNX27,NKAIN1,HS3ST4,SLC25A48,SUSD4,FAM13C,SLC6A15,ATL1,SH3GLB1,RPRD1A,SLC4A10,ELAVL4" MicroRNA hsa-miR-549:mirSVR_lowEffct hsa-miR-549:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-36 1.31E-32 3.84E-35 3.53E-34 93 1466 "PRR5L,ACER3,ACLY,CNTNAP3,ADGRV1,EYA1,IL17D,MDM4,KLHL32,WAC,SORCS1,TUBB4A,NLGN4X,SLC44A5,SEMA6A,UNC79,MOBP,SOX6,SGIP1,ITSN1,ANXA7,GAS7,SLITRK3,AQP4,ZNF365,RPH3A,SLC1A7,SPHKAP,DLL3,ATM,SON,SALL3,KIF1B,NPAS3,C11orf87,RGL1,NEUROD1,CAMTA1,UNC5D,TMEM136,GPM6B,FAM69C,CACNA1E,TCF7L2,PTBP2,CAMK2G,GRIA1,GRIA4,GRID1,GRIK2,TJP1,TNS1,CDH10,MAGI1,ZNF384,PDE1C,CA14,CADM1,ANLN,ST8SIA5,CNTN1,PRRX1,POU3F2,MED1,ATRNL1,DOCK7,EDRF1,BRINP3,PLPPR5,PMEPA1,PRDM2,RGMA,CSDE1,KCNA1,OLFM3,KCNA4,SMG7,PLPPR4,KCNC1,PTPRO,KCNH1,PCDH15,NAV2,DLG2,DLG3,ABI1,L1CAM,JMJD1C,FAM135B,SSPN,RBM12,ABI2,EN2" MicroRNA hsa-miR-21*:mirSVR_lowEffct hsa-miR-21*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.77E-36 1.50E-32 4.38E-35 4.01E-34 99 1667 "RABEPK,ATAT1,RTKN,CSMD3,RTN1,SORCS1,LINC00461,SEMA6A,MOBP,SGIP1,ANK3,PKP4,PPM1E,NTNG1,SLC8A3,NSG2,SLC14A1,TMEM108,EIF4G3,TNIK,ZCCHC24,EMC1,TTLL9,NCAM1,COLGALT2,GFRA1,NEUROD1,MLC1,ZNF638,LUZP2,MYRF,MMD2,BTRC,TMEM136,KLHL4,TBX15,PRUNE2,CACNA1E,TCF12,DIRAS1,AZIN2,CAMK2A,GRIA1,SHISA7,TMEM25,TGFBR3,ZFP91,KCNK10,MAEL,HRH3,LGI1,TPM3,ACOT7,BEST3,HMGB1,TUB,TMEFF2,TLX1,NOMO2,CCSER2,OPALIN,CELF5,BTF3L4,FAAP20,ACBD5,CRMP1,ATRNL1,PRKACB,PRKCG,PRKCZ,PUM1,EDRF1,NOS1AP,MASP1,TOX,ANKS1B,SYNC,DNAJC6,CNIH3,DKFZp779M0652,PRDM2,PTPRE,SRGAP3,KCNMA1,KIF2A,DPP6,ATG16L1,GOPC,RASGRF1,RET,ARHGEF10L,ZNF248,SSPN,SH3GLB1,ABI2,CBLN2,RAVER2,EPB41,EPB41L1" MicroRNA hsa-miR-1225-3p:mirSVR_lowEffct hsa-miR-1225-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.87E-36 1.55E-32 4.52E-35 4.14E-34 83 1158 "DPF1,SERPINA3,ABAT,PAQR6,FAM43B,RTKN,KCNIP2,SLC25A25,NDRG2,ADARB2,LRRTM4,DISP3,FGF14,SLC30A10,TRIM46,ASRGL1,CNIH2,PKP4,NTNG1,BCAS1,KIAA1614,SLC2A5,MADD,LRRC55,ARHGAP5,YPEL4,SLC8A3,MT3,SCMH1,ASCL1,ASPH,MTR,MYT1L,SOX5,SOX10,ZSWIM8,TTLL9,NPAS3,RAP1GAP2,NFASC,ALDH1L1,NHLH1,ANO4,GRIA1,LINC00839,PTPN5,DAAM2,TNS1,PCSK2,PLEKHB1,DLGAP3,NRXN2,CAMKV,TJP2,FADS2,FTO,C11orf49,SLC25A27,IFFO1,PTPA,TENM4,NKAIN4,PRKAB2,PRKACB,PRKCG,HES5,PHYHIP,GON4L,PRTFDC1,COPS7A,KCNC1,SV2A,KCNJ9,KCNK1,DLG2,KLRC2,DNM2,BSDC1,SEC61A2,CACNG7,ELAVL4,YY1AP1,EPB41" MicroRNA hsa-miR-130b*:mirSVR_highEffct hsa-miR-130b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-36 1.59E-32 4.59E-35 4.22E-34 94 1502 "RABEPK,CSMD2,MDM4,CSMD3,KLHL32,GALNT13,ADD3,WAC,SORCS1,GRAMD1B,NLGN4X,SLC44A5,FCGR1A,TOMM40L,SCN3A,ASIC4,HPCAL4,SELL,ASRGL1,CDC42BPA,ANK2,PPFIA1,ITSN1,ANXA7,NTNG1,GPAM,ST3GAL3,ZNF365,SLC8A3,ASCL1,CAPRIN2,ASPH,SMARCE1,NRG3,EIF4G3,SOX1,ILDR2,JPH4,EMC1,KIF1B,NPAS3,LMO3,SMOC1,GLS,GNAS,ANO4,CACNB2,ZEB1,GRIA1,GRIN1,OPCML,FBXL16,TMEM9,TMEM257,PCDH9,TPM3,PDYN,CASC2,HEPACAM,NRXN1,PIK3CD,PMP2,P2RY12,CP,CHD1L,PPP2R5C,SNCAIP,FEZ1,PRKACB,DOCK7,DZIP3,PLPP4,PRKCZ,USP54,ZBTB16,TOX,WBP1L,DPYSL5,BDNF-AS,ZC3H11A,PTPRE,NTM,RABGAP1L,DLG2,SLC17A6,C12orf4,DSCAM,DTNA,SLC6A15,TTLL7,SSPN,SLC4A10,ELAVL4,EPB41L2" MicroRNA hsa-miR-380:mirSVR_highEffct hsa-miR-380:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.98E-36 1.61E-32 4.66E-35 4.27E-34 107 1946 "SERPINA3,ACER3,ADGRV1,CSMD2,F3,DSCAML1,ADD3,GRAMD1B,FCGR1A,LINC00461,LRRC7,FHL1,ELMOD1,CDC42BPA,ANK3,ITSN1,SH3GL2,APC,NLGN1,API5,SHTN1,ZNF365,ARHGAP5,SLC8A3,CCDC88A,DACH2,SCG3,SPHKAP,SORCS3,ASTN1,SMARCE1,RCOR3,SNAP25,ATP1A2,ENKUR,NAP1L2,LMO3,CLASP2,NDUFA5,ZNF302,ERBIN,RGL1,RND1,NHLH1,SYT4,KAZN,ADGRL3,KLHL4,GPM6A,LILRA1,TCF7L2,ZEB1,TCF12,P2RX7,KCNK10,PCDH8,CDH10,TPD52,TPM4,PCSK2,MAGI1,ZMYND8,MS4A7,TMEFF2,HEPACAM,CADM1,NRXN1,PMP2,MFSD4A,SNCAIP,KCNT2,PRKACB,RAB39A,PUM1,GON4L,SPIRE1,SYNC,LRRTM3,ITGAV,PTHLH,PRDM2,HP1BP3,LRP8,CSDE1,KCNA4,OCIAD1,PTPRD,PTPRE,SRGAP3,RABGAP1L,KIF2A,TMEM255A,ABI1,GNE,FAM13C,DBX2,DTNA,RTN4,ABCC9,SLC6A15,ZYG11B,JMJD1C,SSPN,RPRD1A,ELAVL4,TMEM100,EPB41L1" MicroRNA hsa-let-7f-2*:mirSVR_highEffct hsa-let-7f-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.05E-36 1.65E-32 4.76E-35 4.36E-34 101 1737 "ASIC1,ACHE,EYA1,LDLRAD3,CSMD2,SORCS1,NLGN4X,LRRTM4,ELMOD1,SFPQ,ANK3,APBA2,NTNG1,MAGI3,JAKMIP3,MIER1,SLC1A6,SLC14A1,ASPH,SMARCE1,ATP1A2,SON,MYBPC1,B3GALT2,ZCCHC24,NASP,LMO3,C11orf87,NDUFA5,SMOC1,ERBIN,RGL1,NEUROD1,RHBDL3,ZNF638,LUZP2,DDHD2,CAMTA1,NODAL,PRUNE2,CACNB2,TCF7L2,PTBP2,EML4,GRIA4,GRM3,FBXL16,TLL2,TMEM257,PAH,PCDH8,TPD52,PCSK2,PDE2A,PRMT8,LINC01102,BEST3,TMEFF2,NLGN3,CADM1,CCSER2,FTO,PRRX1,MFSD4A,ETNPPL,CRLS1,SNCAIP,PPP3CB,VCAN,PHACTR3,RBPJ,PRKACB,FMN2,NRSN1,MAPK10,MASP1,TOX,BDNF-AS,CADM2,KCNC1,NTM,PCDH15,DLG3,TMEM255A,SLC17A6,GOPC,FAM13C,DBX2,DTNA,RTN4,SLC6A15,RET,RFX4,FAM135B,ARHGEF10L,ZNF248,RNF220,PIANP,RBM12,RPRD1A,LMO1" MicroRNA hsa-miR-519e*:mirSVR_highEffct hsa-miR-519e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.09E-36 1.67E-32 4.80E-35 4.41E-34 94 1503 "ADGRV1,RTKN,KLHL32,ADD3,CDC7,SORCS1,GPR158,KIAA1109,SGIP1,ITSN1,SLITRK3,ST3GAL3,API5,SHTN1,ZNF365,RUFY2,SLC8A3,ASCL1,ASPH,SMARCE1,RCOR3,ATM,ATP1A2,NRG3,MEGF11,CAB39,ARPP21,ADAM15,KIF1B,C11orf87,NDUFA5,NEUROD1,GANAB,AJAP1,ARHGEF7,ZNF638,LUZP2,DDHD2,CACNA1A,TCF12,PTBP2,GRIA1,GRIA2,GRIA4,MAEL,CDC42,PTGDR2,SEZ6L,LGI1,TPM3,PDE1A,PDE3B,LINC01102,ZMYND8,SEMA5B,BTF3L4,CHD1L,MED1,CRLS1,FEZ2,DZIP3,PKN2,PLD5,USP54,PUM1,NOS1AP,BRINP3,ZNF385B,PSMD13,DNAJC6,CADM2,PRDM2,HP1BP3,COPS7A,CEP170,KCNA4,OCIAD1,PTPRD,SMG7,RABGAP1L,CCDC3,KCNK2,KIF2A,SUSD4,PAK5,ABCC9,RFX4,ZNF248,SEC61A2,EFNA3,RERGL,RAVER2,RASGRP2,BAALC" MicroRNA hsa-miR-588:mirSVR_lowEffct hsa-miR-588:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.22E-36 1.75E-32 5.00E-35 4.59E-34 100 1704 "ZFYVE27,MAP6,TMEM74,CLIP1,SORCS1,GPR158,HOGA1,AGT,KIAA1109,ASIC4,MOBP,FOXG1,FOXM1,CDC42BPA,RASA3,PI16,GPAM,ST3GAL3,CLSTN1,AQP4,ZNF365,RPH3A,SLC1A7,PKNOX2,SLC6A9,CCDC88A,SHANK2,LGI3,MTR,KBTBD12,NRG3,SON,WDTC1,KIF21B,NEK6,IDI2-AS1,NFASC,GJB1,ABCC8,CASTOR3,ZNF638,NKX2-2,GNAS,TMEM136,KLHL4,ANO4,TBX15,DDR1,DIRAS1,NUDT21,PCDHGA3,CECR2,GRIA1,TGFBR3,FBXL16,C1orf94,TPD52,PCSK2,PDE1A,PRMT8,ZMYND8,HPSE2,ASIC3,GDAP1L1,CPT1C,CCDC136,PLXNB3,CNTN1,MEAF6,MFSD4A,PPP2R5C,PPP3CB,RGS6,MICAL2,ATRNL1,PLCH2,KIAA0408,WBP1L,RGMA,CSDE1,STMN4,KCNJ9,TMCC2,ARNT2,KCNK1,SNX27,HS3ST4,RAB3IL1,DPP6,ATG16L1,DBX2,DTNA,SLC6A15,RFX5,RGR,ARHGEF10L,TTLL7,ABI2,PRRT4,BAALC" MicroRNA hsa-miR-32:mirSVR_lowEffct hsa-miR-32:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.86E-36 2.09E-32 5.97E-35 5.48E-34 103 1811 "EPS8,C1orf194,ACER3,SYNDIG1,EYA1,ADARB2,ADD3,ERMN,GPR158,TESK2,LINC00461,FGF1,LRRC7,BCAR3,UNC79,FOXG1,AMPH,ANK2,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,ARHGAP5,SORCS3,ASTN1,ALDH4A1,GABBR1,MYT1L,AHCYL1,ENKUR,C11orf87,ERBIN,NEUROD1,NFIA,GLS,NKX2-2,DDHD2,BTRC,KLHL4,TBX15,GPM6B,EML4,VSTM2A,GRIA4,GRIK2,PTPN5,TMEM257,REPS2,CDC42,PCDH8,PCDH9,DCLK1,LGI1,TPD52,PIRT,PDYN,CHGA,CASC2,TMEFF2,JAM2,CADM1,KIAA1549L,CAMKV,BTF3L4,SPATA6,CHD1L,CRLS1,PPP2R5C,PPP3CB,RGS6,PHACTR3,PRKAB2,PRKACB,DZIP3,PRKCG,PKN2,NOS1AP,ZNF385B,SIRPA,PMEPA1,PRDM2,HP1BP3,KCNA1,OCIAD1,NTM,KCNK1,KCNMA1,SNX27,C12orf4,ABI1,SLC6A15,JMJD1C,INSYN2,RLBP1,SH3GLB1,RERGL,ABI2,FGFBP3,RCAN2" MicroRNA hsa-miR-484:mirSVR_lowEffct hsa-miR-484:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.88E-36 2.10E-32 5.99E-35 5.49E-34 104 1846 "LOC100128239,ACLY,SYT9,ATAT1,LDLRAD3,MDM4,KCNIP2,ADD3,SCN3A,LINC00461,ASIC4,MOG,ERICH3,SORBS1,BCAS1,SLC8A3,DACH2,CADPS,SNCB,ATP1A2,USP33,MYH7,ARPP21,KIRREL3,NEUROD1,AJAP1,ARHGEF7,WWC1,ANO4,ZEB1,CAMK2A,NUCB1,AKNA,RFFL,TF,CCKBR,P2RX7,TMEM9,TNR,PCDH9,CDH8,IGFN1,LINC01102,ZMYND8,CHGA,PFKFB3,PLEKHB1,CAMKV,SEMA5B,PIK3CD,NMT2,CCSER2,TJP2,FADS2,SLC25A27,BEST1,PRRX1,CHD1L,SF1,CRMP1,PTPA,NKAIN4,ATRNL1,PLCH2,CMTM5,PLPP4,IGSF1,MAPK10,NOS1AP,MASP1,WBP1L,PHYHIP,GON4L,CNIH3,PRDM2,COPS7A,CSDE1,BLOC1S6,C1orf109,PTPRZ1,SV2A,KCNMA1,PEX5,DLG2,HS3ST4,DNAH9,DPP6,RALGDS,SUSD4,GOPC,RASGRF1,DBX2,DTNA,SLC6A15,ZYG11B,CAMK1G,RET,PHC2,SLC39A12,RBM12,SLC4A10,BSCL2,RPE65,EPB41L2" MicroRNA hsa-miR-21*:mirSVR_highEffct hsa-miR-21*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.91E-36 2.12E-32 6.02E-35 5.52E-34 84 1193 "RTN3,DUSP27,EYA1,F3,CLIP1,ADD3,NLGN4X,SLC44A5,LRRTM4,FGF14,SLC30A10,PPFIA1,ITSN1,ANXA7,DOCK10,MAGI3,SHTN1,AQP4,MSR1,CAPRIN2,ASPH,SMARCE1,RCOR3,NRG3,PHYHIPL,SON,GAD2,AHCYL1,IDI2-AS1,ZNF302,ERBIN,KIRREL3,ADHFE1,ARHGEF7,GLS,VAMP1,CAMTA1,CAMSAP2,UNC5D,WWC1,GPM6A,TCF7L2,EML4,VSTM2A,GRIA2,GRIA4,GRID1,AIFM1,PAX6,CDC42,PDE4B,CADM1,NMT2,FTO,FAT3,CNRIP1,CRLS1,PPP3CB,VCAN,PLPP4,SYTL2,SIRPA,ELMO1,STMN4,OLFM3,OCIAD1,SMG7,PTPRO,DLG2,NKAIN1,TMEM255A,C12orf4,FAM13C,DTNA,ABCC9,SLC6A15,ZYG11B,TTLL7,RNF220,RBM12,SLC4A10,OLIG2,SEZ6,BAALC" MicroRNA hsa-miR-4308:mirSVR_lowEffct hsa-miR-4308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.22E-36 2.29E-32 6.47E-35 5.94E-34 90 1380 "ZFYVE27,ACER3,EMID1,EXTL1,MEG3,ECSIT,CSMD3,KLHL32,SORCS1,FOXRED2,TOMM40L,LINC00461,FOXG1,SOX6,TRIM46,ANK2,PPFIA1,DGKZ,KIAA1614,RPH3A,CCDC88A,SLC14A1,NAXD,ALDH4A1,ATP1A2,SON,KIF21B,AHCYL1,TTLL9,TTC9B,NCAM1,SMOC1,GFAP,NCDN,NELL1,KIRREL3,ADHFE1,FAM168A,C1QC,SEMA4A,MMD2,GOLGB1,ANO4,TMEM151B,AKNA,CYB561A3,OPCML,MFSD2A,P2RX7,ZFP91,RBFOX2,LGI1,PDE1C,PDE2A,IGFN1,PRMT8,FNDC5,ST8SIA5,POU3F2,CHD1L,PPP2R5C,TENM4,MICAL2,OSBPL3,RBPJ,CMTM5,PLPP4,NOS1AP,WBP1L,GON4L,COPS7A,PTPRE,C1orf109,KCNJ11,PEX5,WIPF2,FAM57B,DTNA,NUP214,RET,PHC2,VANGL2,SSPN,SH3GLB1,ABI2,RPE65,PRRT4,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-146b-3p:mirSVR_lowEffct hsa-miR-146b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.71E-36 2.55E-32 7.20E-35 6.61E-34 92 1446 "ZFYVE27,ACHE,MBP,MEG3,ADGRV1,CSMD2,F3,GALNT13,FABP7,NLGN4X,TOMM40L,SNX32,HOGA1,LRRTM4,FGF14,ELMOD1,MOG,ANK3,ITSN1,MAGI3,BCAN,MSR1,YPEL4,DACH2,CAPRIN2,ASTN1,SCN3B,ZCCHC24,SOX10,ADAM15,NPAS3,NFASC,C11orf87,ERBIN,RCOR2,RGL1,GANAB,CASTOR3,PCDH11X,PSRC1,PRUNE2,PTBP2,NUDT21,NUMA1,AKNA,GRIA4,CRB1,LEFTY2,USP2,MAEL,TPM3,TPM4,GPR37L1,MS4A7,GDAP1L1,CPT1C,NMT2,OPALIN,CELF5,COL9A2,PRRX1,NXPH1,MFSD4A,CHD1L,MED1,PNKD,CRMP1,CRLS1,PPP3CB,PLCH2,RIMS4,SDC3,FMN2,FAM131B,WBP1L,LRRTM3,PRDM2,HP1BP3,KCNA1,KCNA4,PTPRD,PARD6A,KCNJ10,RAB3IL1,RAB5B,DNM2,FAM66C,PARP11,SLC6A15,FAM135B,SEC61A2,GPR61" MicroRNA hsa-miR-4255:mirSVR_lowEffct hsa-miR-4255:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.38E-36 2.91E-32 8.20E-35 7.52E-34 97 1613 "SERPINA3,LGR4,DUSP27,FAM43B,KLHL32,KLRC4,SLITRK1,GRAMD1B,ADORA1,CHST15,UNC79,ELMOD1,MOBP,FOXG1,SOX6,TRIM46,CDC42BPA,ANK2,ANK3,PPFIA1,GPAM,API5,MIER1,SLC8A3,SORCS3,PALLD,DKK3,NMNAT2,ARPP21,NEK6,NAP1L2,NPAS3,NFASC,COLGALT2,KIRREL3,VAMP1,SYT4,DCLK2,UNC5D,TMEM136,KLHL4,GPM6B,DDR1,ZEB1,PTBP2,CAMK2A,VSTM2A,GRIA2,RFFL,CRB1,TLL2,REPS2,CDC42,DCLK1,TPD52,MAGI1,CHGA,NLGN3,GDAP1L1,SERPINE2,ZFYVE9,NEGR1,ANLN,BEST1,PNKD,CRLS1,PPP3CB,PKN2,PLD5,CTNND1,PUM1,NOS1AP,MASP1,KIAA0513,PTCH1,ITGAV,JAKMIP2,CADM2,LRP8,MAGI2,PTPRZ1,SRGAP3,KCNJ10,KCNK2,NKAIN1,KIF2A,SLC25A18,DTNA,RFX4,ZNF248,SEC61A2,RBM12,RPRD1A,ABI2,VWA5A,ELAVL3,BAALC" MicroRNA hsa-miR-4264:mirSVR_lowEffct hsa-miR-4264:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-36 2.97E-32 8.34E-35 7.65E-34 96 1580 "TTYH1,ABAT,ACER3,CDHR1,RTN3,MEG3,ADGRV1,EYA1,KCNIP2,RTN1,PNMA8B,ERMN,FCGR1A,SCN4B,SEMA6A,SH3GL2,SESN3,APC,NTNG1,ST3GAL3,LRRC4C,MADD,PKNOX2,SLC8A2,DACH2,SCMH1,DLL3,ASPH,PALLD,SON,B3GALT2,ARPP21,ADAM15,FXYD6,SPART,GFAP,PHLDB1,CASTOR3,ZNF638,KAZN,CDK5R2,MMD2,ADGRL3,ATF7,TCF7L2,AZIN2,SYT6,AKNA,GRIA1,GRIA4,CRB1,LEFTY2,MFSD2A,TLL2,TNFRSF1B,CDH8,LGI1,PDE3B,FNDC5,ADGRG1,ANO5,CASC2,SLC22A6,PIK3CD,A2ML1,COL9A2,NSD2,CHD1L,SF1,CRMP1,SNCAIP,PRKACB,FMN2,CMTM5,PLD5,IGSF1,CTNND1,TOX,WBP1L,PTAFR,ITGAV,HP1BP3,COPS7A,CEP170,OCIAD1,PTPRD,PTPRZ1,NTM,PCDH15,RAD52,ATG16L1,DBX2,JMJD1C,RGS10,ZNF248,UEVLD" MicroRNA hsa-miR-613:mirSVR_lowEffct hsa-miR-613:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.45E-36 3.49E-32 9.78E-35 8.97E-34 103 1822 "MAP6,SYT9,MRVI1,CSMD3,KLHL32,WAC,SORCS1,ADORA3,FCGR1A,DRAXIN,GPR158,TESK2,SCN3A,LINC00461,FGF14,SEMA6A,UNC79,MOBP,MOG,AMPH,SFPQ,CDC42BPA,DOCK10,NTNG1,CACHD1,SYBU,SHTN1,LRRC55,SLC8A2,SLC8A3,SHANK2,NSG2,DLL3,TMEM151A,EIF4G3,TNIK,SOX10,ENKUR,TTLL9,CPLX2,NFASC,NCAM1,BCL2L2,NDUFA5,GFRA1,NCDN,SEPT3,FAM168A,VAMP1,GNAS,UNC5D,MMD2,BTRC,CACNA1A,CACNB2,LILRA1,PTBP2,SYT6,GRIA2,GRIA4,GRIK2,OPCML,CRB1,TGFBR3,ZDHHC22,PAX6,TNR,ACOT7,CASC2,HEPACAM,CADM1,NRXN1,OPALIN,TJP2,ATRNL1,NCAN,CTNND1,CTNND2,BRINP3,TOX,WBP1L,ANKS1B,GON4L,PLPPR5,PRDM2,LRP8,CEP170,MAGI2,SRGAP3,PCDH15,KCNMA1,HS3ST4,WIPF2,SUSD4,GNE,ZYG11B,FAM135B,SH3GLB1,RERGL,ABI2,TMEM100,EPB41L1,RCAN2" MicroRNA hsa-miR-1259:mirSVR_lowEffct hsa-miR-1259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.54E-36 3.54E-32 9.89E-35 9.08E-34 106 1928 "EPS8,ACER3,LGR4,ADGRV1,IL17D,CSMD3,ADD3,SORCS1,GRAMD1B,SNX30,TESK2,FGF1,SLC30A10,ANXA7,NTNG1,CCDC80,ST8SIA1,PAAF1,MSR1,SLC8A3,CCDC88A,SLIT1,SORCS3,TMEM108,ATM,NRG3,SON,MYT1L,B4GALNT1,ARPP21,KIF1B,ADGRB2,NAP1L2,ZNF302,AJAP1,SLCO1C1,NFIA,PCDH11X,ZNF638,LUZP2,CAMTA1,UNC5D,BTRC,KLHL4,GPM6A,ATF7,VXN,GRIA2,GRIA4,RFFL,GRIK2,GRIK3,CRB1,KCNK10,DAAM2,MAEL,PCDH8,MAGI1,ZNF384,PDE1C,BEST3,TMEFF2,HEPACAM,NLGN3,FTO,PMP2,MEAF6,FAT3,CNRIP1,RNF14,PHACTR3,PRKAB2,DOCK7,DZIP3,PLD5,NRSN1,PUM1,EDRF1,NOS1AP,TOX,SYTL2,GON4L,SPIRE1,ZNF385B,PTCH1,PLPPR1,JAKMIP2,PRDM2,HP1BP3,COPS7A,OCIAD1,PLPPR4,SRGAP3,NTM,KCNK1,KCNK2,KIF2A,GNE,DTNA,RTN4,SLC39A12,ABI2,VWA5A,C2orf80,TMEM100,EPB41L1" MicroRNA hsa-miR-381:mirSVR_highEffct hsa-miR-381:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.14E-36 3.87E-32 1.08E-34 9.88E-34 94 1519 "DPF1,EPS8,SYNDIG1,WLS,CSMD3,ADORA3,NLGN4X,GPR158,TESK2,FGF1,FOXG1,SFPQ,ERICH3,ANK3,PPFIA1,PPM1E,DGKD,SORBS1,SYBU,SHTN1,PAAF1,MIER1,RUFY2,MSR1,ASPH,EIF4G3,PHYHIPL,KIF21B,B4GALNT1,ARPP21,NEK6,KIF1B,NAP1L2,NCAM1,LMO3,NEUROD1,GANAB,VAMP1,PCDH11X,POPDC3,ANO4,TBX15,CACNB2,LILRA1,ZEB1,CECR2,GRIA1,GRIA2,RFFL,GRM3,TGFBR3,AIFM1,PCDH8,CDH10,PCSK2,MAGI1,PDE1C,HMGB1,NRXN1,A2ML1,CCSER2,BEST1,BTF3L4,ACBD5,MFSD4A,POU3F2,FEZ2,OSBPL3,RBPJ,PRKACB,FMN2,ANKS1B,TOMM20,PTCH1,ITGAV,LRP8,BLOC1S6,ZC3H11A,KCNA4,OCIAD1,RABGAP1L,PCDH15,SNX27,DNM2,SLC17A6,DPP6,FAM13C,SLC6A15,ZNF248,RPRD1A,VWA5A,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-217:mirSVR_lowEffct hsa-miR-217:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.70E-36 4.17E-32 1.16E-34 1.06E-33 102 1791 "RABEPK,LGR4,CSMD2,ARID1A,KLHL32,WAC,PNMA8B,SORCS1,GPR158,HOGA1,SCN4B,FGF1,SEMA6A,UNC79,FOXG1,USP28,ITSN1,PPM1E,NLGN1,API5,SHTN1,SLC2A5,SPHKAP,DDX25,SMARCE1,SNAP25,NRG3,EIF4G3,PALLD,USP33,ZSWIM8,ENKUR,JPH4,B4GALNT1,SALL3,ADAM15,NCAM1,C11orf87,ALDH1L1,RGL1,ADHFE1,SEPT3,NFIA,PCDH11X,POPDC3,CAMTA1,ANO4,ATF7,ACSL6,VWC2,TCF7L2,PTBP2,GRIN1,OPCML,GUCY1A1,TLL2,NEURL1,DCLK1,ARHGAP19,LGI1,TPD52,PDE3B,ANO5,KIAA1549L,CCSER2,OPALIN,DNAJC12,FTO,SULT4A1,NSD2,FAT3,ATCAY,ACBD5,POU3F2,PNKD,CRLS1,TENM4,VCAN,RBPJ,PRKAB2,CTNND1,TOX,ZNF385B,LRRTM3,PRDM2,KCNA4,PTPRD,PLPPR4,PTPRZ1,KCNK2,DLG2,KLRC3,PLEKHB2,FAM66C,ZYG11B,RET,RFX4,SSPN,SH3GLB1,ARHGAP12,SLC4A10,EN2" MicroRNA hsa-miR-1208:mirSVR_lowEffct hsa-miR-1208:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.36E-36 5.07E-32 1.40E-34 1.29E-33 106 1936 "EPS8,SYT9,LGR4,SYNDIG1,MDM4,ADORA3,KIAA1109,FGF1,LRRC7,GPAM,DGKD,CACHD1,API5,ZNF365,URGCP,SHANK2,SORCS3,SMARCE1,B3GAT1,NRG3,GABBR1,ZSWIM8,AHCYL1,JPH4,SALL3,TTLL9,GART,CPLX2,NAP1L2,FXYD6,NFASC,LMO3,C11orf87,BCL2L2,SEPT3,FAM168A,ZNF638,CAMTA1,UNC5D,CNTN2,TMEM136,VWC2,TCF12,PTBP2,CAMK2G,SYT6,GRIK2,GRM3,OLR1,TMEM25,USP2,P2RX7,AIFM1,TMEM257,NEURL1,ZFP91,ATG4C,CDC42,DCLK1,TPM3,NLGN3,GDAP1L1,CADM1,DNAJC12,SLC36A4,NSD2,CRLS1,PPP3CB,FEZ2,PRKACB,PKN2,CTNND2,HES5,KIAA0408,BRINP3,KIAA0513,GON4L,TOMM20,PSMD13,OLFM3,KCNA4,PTPRE,PTPRO,NTM,RABGAP1L,KCNJ10,KCNK2,PCDH15,KCNMA1,KIF2A,PID1,PLEKHB2,DSCAM,RET,INSYN2,ZNF248,RLBP1,SEC61A2,RNF220,RPRD1A,ABI2,ARHGAP12,RAVER2,SLC4A10,C2orf80,UEVLD" MicroRNA hsa-miR-4318:mirSVR_lowEffct hsa-miR-4318:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.91E-36 5.37E-32 1.48E-34 1.36E-33 98 1659 "RABEPK,ADCY2,ADD3,TMEM156,FOXRED2,KIAA1109,BCAR3,ERICH3,PKP4,DOCK10,SORBS1,SYBU,NLGN1,ZNF365,RPH3A,ARFGAP2,SLC8A3,CCDC88A,SHANK2,SCG3,TMEM108,CCDC181,NMNAT2,ARPP21,NAP1L2,BCL2L2,NELL1,FAM168A,MLC1,SYT4,LUZP2,KAZN,KLHL4,TCF12,HAP1,PTBP2,SYT6,GRIA4,GPR88,OLR1,USP2,TMEM9,DAAM2,REPS2,CDH8,RBFOX2,LGI1,TPD52,PCSK2,ZNF384,PDE4B,ZMYND8,HMGB1,TMEFF2,NLGN3,DLGAP3,BTF3L4,FAT3,CRLS1,OSBPL3,ATRNL1,VCAN,CTNND2,NOS1AP,KIAA0408,ZBTB16,TOX,SYTL2,DPYSL5,PLPPR5,CA10,HP1BP3,CSDE1,MAGI2,KCNA6,C1orf109,SV2A,RABGAP1L,KCNK2,KCNMA1,NAV2,RAB3IL1,PID1,DNM2,SUSD4,DSCAM,RTN4,ZYG11B,RFX5,RGS7,FAM135B,ARHGEF10L,ELAVL4,C2orf80,EN2,EPB41L1,EPB41L2,SEZ6" MicroRNA hsa-miR-199a-5p:mirSVR_lowEffct hsa-miR-199a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-35 5.81E-32 1.60E-34 1.47E-33 103 1833 "TTYH1,ACHE,MBP,SYT9,ACTN2,FAM43B,LDLRAD3,CSMD3,ERMN,FCGR1A,TOMM40L,HOGA1,SCN3A,SEMA6A,ASIC4,ANK2,DACH2,CADPS,SCMH1,NAXD,ASPH,BRINP2,SMARCE1,NRG3,PALLD,SOX5,GAD2,ARPP21,TTLL9,ADAM15,ADGRB2,NAP1L2,BCL2L2,ALDH1L1,STOX1,SMOC1,NEUROD1,GANAB,MLC1,ARHGEF7,GNAS,MYRF,BTRC,TMEM136,KLHL4,CACNB2,PTBP2,NUDT21,TMEM151B,VSTM2A,AKNA,GRID1,ATP13A2,OMG,CCKBR,LINC00839,TMEM9,AIFM1,ZDHHC22,HPS5,CDC42,TNR,CDH8,CHRM1,CHRNB2,CADM1,NEGR1,A2ML1,SULT4A1,NSD2,PNKD,TENM4,NRSN1,PUM1,GON4L,BDNF-AS,PTHLH,PRDM2,RGMA,OLFM3,PTPRD,PTPRE,PLPPR4,KCNC1,SRGAP3,TMCC2,ARNT2,DNAH9,TMEM255A,SLC17A6,FAM66C,DPP6,RASGRF1,GNE,DBX2,BSDC1,NUP214,RFX4,JMJD1C,ELAVL4,TMEM100,EPB41L1,UEVLD" MicroRNA hsa-miR-194*:mirSVR_lowEffct hsa-miR-194*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-35 5.85E-32 1.61E-34 1.47E-33 107 1975 "PRR5L,MAP6,ATAT1,MDM4,ADAR,SLITRK1,NLGN4X,TOMM40L,HOGA1,PLA2G6,FGF14,SEMA6A,ASIC4,FHL1,MOG,C1orf61,TRIM46,SFPQ,SGIP1,PI16,PPFIA1,APBB1,ZNF365,KIAA1614,LRRC55,NSG2,CADPS,CAPRIN2,ASPH,ASTN1,B3GAT1,ADGRA1,NRG3,DKK3,GABBR1,NMNAT2,ENKUR,ARPP21,KIF1B,NFASC,STOX1,ERBIN,ADHFE1,NEUROD1,SLCO1C1,LUZP2,CDK5R2,BTRC,PSRC1,WWC1,CNDP1,KLHL4,ANO4,DDR1,CACNB2,GPR17,GRIA4,RFFL,CYB561A3,OPCML,TGFBR3,FBXL16,TIE1,TMEM257,REPS2,SEZ6L,ARHGAP19,TPM3,ZNF384,PDE1C,PRMT8,ASIC3,TUB,CHRNB2,NSD2,PNKD,PPP3CB,OSBPL3,ATRNL1,CTNND1,FGFR1OP2,KLK6,SYTL2,LRRTM3,BDNF-AS,ELMO1,MAGI2,ZC3H11A,PLPPR4,NTM,KCNJ4,KCNJ10,KCNN3,RAB3IL1,RALGDS,BSDC1,ZYG11B,NUP214,RET,USH1C,FAM135B,INSYN2,PIANP,RBM12,GPR61,BSCL2,BAALC" MicroRNA hsa-miR-646:PITA hsa-miR-646:PITA_TOP PITA 1.10E-35 5.93E-32 1.63E-34 1.49E-33 54 437 "ASIC1,MAPT,CCDC80,CACHD1,CLSTN1,ARHGAP5,WDTC1,MYT1L,SOX5,KIF21B,CAB39,ZSWIM8,AHCYL1,SALL3,DNER,CLASP2,RGL1,NEUROD1,GANAB,FAM168A,CAMTA1,CAMSAP2,WSCD1,CAMK2A,SYT6,GPR88,CDC42,TNS1,DCLK1,RBFOX2,HRH3,TPM3,ACOT7,ANLN,BTF3L4,NXPH1,ACBD5,ATRNL1,PRKCG,PKN2,USP54,CTNND1,CADM2,CEP170,ZC3H11A,SMG7,SRGAP3,DLG3,KIF2A,RTN4,FAM135B,INSYN2,RBM12,RCAN2" MicroRNA hsa-miR-148b:mirSVR_lowEffct hsa-miR-148b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-35 6.37E-32 1.74E-34 1.60E-33 103 1835 "ZFYVE27,ASIC1,ACHE,MBP,CSMD2,MDM4,ADARB2,CLIP1,RTN1,ADCY2,GRAMD1B,SCNN1D,LRRC7,GOLGA7B,SELL,ERICH3,ANK2,RASA3,APC,SLITRK3,TACC2,SYBU,SHTN1,SFMBT2,PKNOX2,CCDC88A,SHANK2,CAPRIN2,MTR,ASTN1,RCOR3,SNAP25,NRG3,EMC1,NCAM1,CLASP2,BCL2L2,ALDH1L1,ERBIN,INKA2,RCOR2,NELL1,AJAP1,GLS,TMEM136,DDR1,AZIN2,CAMK2A,NUMA1,OPCML,PTPN5,TMEM25,LEFTY2,USP2,MFSD2A,ZDHHC22,RBFOX2,PDE2A,PDE3B,PDE4B,PIRT,ZMYND8,TLX1,ZFYVE9,KIAA1549L,NRXN1,TJP2,FADS2,FTO,VAV2,IFFO1,CHD1L,MED1,MASP1,DPYSL5,LRRTM3,CADM2,ELMO1,PRDM2,HP1BP3,RGMA,CEP170,PTPRE,KCNH1,KCNK1,PCDH15,SNX27,WIPF2,DNAH9,KLRC2,SLC17A6,PLEKHB2,PARP11,ATG16L1,ZNF248,SEC61A2,SLC39A12,VWA5A,SLC4A10,EPB41,EPB41L2,UEVLD,BAALC" MicroRNA hsa-let-7a-2*:mirSVR_highEffct hsa-let-7a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-35 6.47E-32 1.76E-34 1.61E-33 85 1242 "LGR4,RTN3,MEG3,EYA1,ARID1A,KLHL32,DSCAML1,LRRC7,UNC79,ANK1,CNIH2,ITSN1,SH3GL2,DOCK10,NTNG1,SLITRK3,SORBS1,BCAS1,CSPG5,MEGF11,SON,MYT1L,SOX10,SALL3,NEK6,ADGRB2,CLASP2,ZNF302,ERBIN,GFAP,DCAF5,KIRREL3,GLS,DDHD2,CAMTA1,NODAL,ADGRL3,GPM6B,TCF7L2,ZEB1,PTBP2,GRIK3,PTPN5,LEFTY2,TJP1,PCDH8,CDH10,SEZ6L,LGI1,TPM3,MAGI1,HMGB1,NLGN3,CAMKV,A2ML1,DNAJC12,FLRT1,NXPH1,PPP2R5C,MICAL2,PLCH2,WBP1L,TOMM20,LRRTM3,ITGAV,COPS7A,CEP170,MAGI2,SMG7,KCNK1,KCNK2,PCDH15,DNAH9,RASGRF1,FAM13C,DTNA,RFX4,JMJD1C,RGS7,INSYN2,ARHGEF10L,VANGL2,VWA5A,ARHGAP12,TMEM100" MicroRNA hsa-miR-3156:mirSVR_lowEffct hsa-miR-3156:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-35 6.47E-32 1.76E-34 1.61E-33 97 1629 "RABEPK,SDE2,RTN3,MEG3,ADGRV1,ATAT1,MDM4,KCNIP2,ADAR,CLIP1,KLHL32,CDC7,MOG,TRIM46,SFPQ,ASRGL1,ANK2,PPFIA1,PKP4,MAGI3,GPAM,SORBS1,RPH3A,SLC2A5,MSR1,LRRC55,ARHGAP5,SLC8A3,SLCO1A2,CAPRIN2,SMARCE1,B3GAT1,ATM,SNCB,ZSWIM8,ENKUR,NASP,NFASC,C11orf87,NDUFA5,NCDN,NEUROD1,ZNF638,NHLH1,SYT4,UNC5D,BTRC,TMEM136,GPM6B,VWC2,ZEB1,PTBP2,VSTM2A,AKNA,GRIA2,ADAMTS8,OPCML,CRB1,PCDH9,RBFOX2,PDE1A,HMGB1,ASIC3,MS4A7,CADM1,KIAA1549L,BTF3L4,NSD2,RGS6,DZIP3,PUM1,EDRF1,NOS1AP,KIAA0408,PMEPA1,BLOC1S6,PTPRE,PTPRO,C1orf109,PTPRZ1,NTM,KCNJ9,KCNJ10,KCNMA1,NAV2,FAM66C,PARP11,SUSD4,DSCAM,ZYG11B,RFX4,INSYN2,TTLL7,SEC61A2,SLC39A12,RBM12,ELAVL4" MicroRNA hsa-miR-1305:mirSVR_highEffct hsa-miR-1305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-35 6.62E-32 1.79E-34 1.65E-33 104 1871 "CNTNAP3,MEG3,ADGRV1,ATAT1,CSMD2,ARID1A,CLIP1,KLHL32,GALNT13,GPR158,LRRTM4,ACTL6B,MOBP,USP28,PPFIA1,ITSN1,PPM1E,NTNG1,MAGI3,ST3GAL3,MIER1,ASPH,SORCS3,RCOR3,NRG3,PALLD,DKK3,USP33,SON,MYBPC1,B3GALT2,SOX5,CAB39,ARPP21,NEK6,NPAS3,COLGALT2,ALDH1L1,ARHGEF7,GLS,PCDH11X,ZNF638,SYT4,POPDC3,DDHD2,CAMSAP2,PTBP2,EML4,CAMK2A,GRIA1,GRIA4,CRB1,TMEM257,ZFP91,PADI2,PCDH9,CDH8,LGI1,MAGI1,FNDC5,HNRNPK,TMEFF2,CADM1,SPATA6,P2RY12,NXPH1,ACBD5,CNRIP1,MFSD4A,CRLS1,PPP3CB,PRKACB,PUM1,FGFR1OP2,TOX,PLPPR5,TUBB2B,SYNC,LRRTM3,JAKMIP2,BDNF-AS,CADM2,PRDM2,CEP170,BLOC1S6,ZC3H11A,SMG7,KCNC1,PTPRO,PCDH15,DLG3,TMEM255A,SLC17A6,PARP11,DPP6,ATG16L1,JMJD1C,FAM135B,SEC61A2,SSPN,RBM12,RPRD1A,SLC4A10,EN2" MicroRNA hsa-miR-1289:mirSVR_lowEffct hsa-miR-1289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-35 7.28E-32 1.97E-34 1.80E-33 85 1244 "DPF1,ACLY,FAM43B,MRVI1,ATAT1,LDLRAD3,RTN1,FHL1,UNC79,TRIM46,ANK1,ANK2,RUFY2,MSR1,DACH2,SCMH1,SPHKAP,ASPH,TMEM108,ATP1A2,EIF4G3,WDTC1,SOX1,B3GALT2,ARPP21,TTLL9,KIF1B,ADGRB2,NFASC,CLASP2,FGF17,ADHFE1,ARHGEF7,DCLK2,SEMA4A,PTBP2,CAMK2A,VXN,NUMA1,BRSK2,GRIA1,TF,TLL2,TNS1,SEZ6L,TPM4,PDE1A,PRMT8,BEST3,TMPRSS5,CHGA,ASIC3,CHRM1,TLX1,JAM2,CADM1,NEGR1,CPT1C,CCSER2,BEST1,PPP2R5C,CMTM5,PLPP4,CTNND1,NRSN1,PHYHIP,ZNF385B,CEP170,STMN4,KCNA1,PTPRD,NTM,TMCC2,KCNMA1,HS3ST4,KLRC2,DNM2,L1CAM,BSDC1,USH1C,ARHGEF10L,ZNF248,PIANP,CBLN2,PRRT4" MicroRNA hsa-miR-200c:PITA hsa-miR-200c:PITA_TOP PITA 1.36E-35 7.36E-32 1.98E-34 1.82E-33 70 815 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,SLITRK1,ADD3,NLGN4X,GPR158,TESK2,SCN3A,LRRTM4,FOXG1,ERICH3,SGIP1,ANK3,ITSN1,PPM1E,SLC1A2,RUFY2,SNAP25,MEGF11,SOX1,ZCCHC24,CAB39,NAP1L2,NFASC,NCAM1,CLASP2,RGL1,PHLDB1,NFIA,CAMSAP2,WWC1,GPM6A,CACNB2,ZEB1,CECR2,PSD3,TLL2,CDC42,PCDH8,RBFOX2,ARHGAP19,PCSK2,HMGB1,TMEFF2,NEGR1,ANLN,CCSER2,SLC25A27,BTF3L4,COL9A2,NSD2,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,CTNND2,WBP1L,RIMS3,LRRTM3,PTCH1,ZC3H11A,PTPRZ1,KCNK2,GOPC,PAK5" MicroRNA hsa-miR-200b:PITA hsa-miR-200b:PITA_TOP PITA 1.36E-35 7.36E-32 1.98E-34 1.82E-33 70 815 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,SLITRK1,ADD3,NLGN4X,GPR158,TESK2,SCN3A,LRRTM4,FOXG1,ERICH3,SGIP1,ANK3,ITSN1,PPM1E,SLC1A2,RUFY2,SNAP25,MEGF11,SOX1,ZCCHC24,CAB39,NAP1L2,NFASC,NCAM1,CLASP2,RGL1,PHLDB1,NFIA,CAMSAP2,WWC1,GPM6A,CACNB2,ZEB1,CECR2,PSD3,TLL2,CDC42,PCDH8,RBFOX2,ARHGAP19,PCSK2,HMGB1,TMEFF2,NEGR1,ANLN,CCSER2,SLC25A27,BTF3L4,COL9A2,NSD2,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,CTNND2,WBP1L,RIMS3,LRRTM3,PTCH1,ZC3H11A,PTPRZ1,KCNK2,GOPC,PAK5" MicroRNA hsa-miR-660:mirSVR_lowEffct hsa-miR-660:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-35 7.76E-32 2.08E-34 1.91E-33 86 1276 "ACER3,F3,CLIP1,KLHL32,ADD3,CHST15,SCN4B,PLA2G6,DOCK10,APC,PAAF1,ZNF365,SLC7A14,CCDC88A,DACH2,B3GAT1,ATM,MYT1L,SOX5,KIF21B,ENKUR,NKX6-2,KIF1B,ADGRB2,C11orf87,ADHFE1,NEUROD1,ARHGEF7,ZNF638,LUZP2,BTRC,TBX15,GPM6A,NEU4,LILRA1,ZEB1,DIRAS1,NRDC,EML4,GRIA1,GPR88,P2RX7,TLL2,KCNK10,MAEL,DCLK1,TPM3,PRMT8,PDYN,GDAP1L1,CADM1,VAV2,MEAF6,CELF5,BTF3L4,SPATA6,POU3F2,PPP2R5C,ATRNL1,RBPJ,PRKAB2,PRKACB,DZIP3,FMN2,IGSF1,NRSN1,EDRF1,MASP1,ANKS1B,ITGAV,CNIH3,PRDM2,KCNA4,PTPRE,WIPF2,ATG16L1,BSDC1,RFX4,FAM135B,SEC61A2,GPR61,LMO1,VWA5A,RAVER2,ELAVL4,RCAN2" MicroRNA hsa-miR-140-5p:mirSVR_lowEffct hsa-miR-140-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-35 8.39E-32 2.24E-34 2.05E-33 93 1501 "TTYH1,PRR5L,ACER3,WLS,TOMM40L,FGR,BBOX1,SGIP1,ANK3,ITSN1,SH3GL2,MAGI3,API5,LRRC55,NSG2,SCMH1,SLCO1A2,MTR,ASTN1,RCOR3,SNCB,NRG3,TNIK,CADM3,ARPP21,KIF1B,NFASC,BCL2L2,NDUFA5,ERBIN,NELL1,NEUROD1,SEPT3,ZNF638,KAZN,GNAS,CAMTA1,CAMSAP2,UNC5D,CNDP1,PRUNE2,ACSL6,VSTM2A,GRIA4,RFFL,GRIK4,LINC00839,TJP1,MAEL,PAX6,CDH8,ARHGAP19,ZMYND8,HMGB1,TMEFF2,TLX1,PIK3CD,SLC25A27,BTF3L4,POU3F2,PPP3CB,VCAN,RBPJ,ARHGEF4,NRSN1,FGFR1OP2,MASP1,WBP1L,DPYSL5,LRRTM3,CADM2,PRTFDC1,CSDE1,MAGI2,ZC3H11A,OLFM3,PTPRE,KCNC1,RABGAP1L,SNX27,DLG2,KLRC2,FAM66C,DBX2,DTNA,ZYG11B,RFX4,SYT15,RNF220,RBM12,OLIG2,EPB41L1,UEVLD" MicroRNA hsa-miR-27a:mirSVR_highEffct hsa-miR-27a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.55E-35 8.39E-32 2.24E-34 2.05E-33 93 1501 "SYT9,MEG3,EYA1,SLITRK1,GRAMD1B,ADORA1,ADORA3,TOMM40L,TESK2,KIAA1109,FGF1,FGF14,SEMA6A,MOBP,TRIM46,ERICH3,ANK2,ANK3,PKP4,APBA2,MAGI3,GPAM,PAAF1,ARFGAP2,DACH2,ASPH,RCOR3,SNAP25,ATP1A2,TNIK,CAB39,NEK6,TTC9B,KIF1B,NAP1L2,NCAM1,COLGALT2,STOX1,ERBIN,GLS,ZNF638,DDHD2,CAMTA1,CACNA1A,GPM6A,CACNB2,ZEB1,VSTM2A,GRIA4,TF,CRB1,TGFBR3,INA,MAEL,PCDH9,MAGI1,PDE3B,PRMT8,CIART,ADGRG1,CASC2,MS4A7,CADM1,NRXN1,DNAJC12,BEST1,POU3F2,CHD1L,PNKD,CRMP1,VCAN,PKN2,EDRF1,TOX,PTAFR,DNAJC6,CA10,PLPPR1,LRP8,KCNK2,CAB39L,KLRC2,DTNA,RET,JMJD1C,FAM135B,VANGL2,LPAR6,ARHGAP12,C2orf80,EN2,EPB41,RCAN2" MicroRNA hsa-miR-3170:mirSVR_lowEffct hsa-miR-3170:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-35 8.71E-32 2.32E-34 2.13E-33 97 1635 "RABEPK,TTYH1,MAP6,ACLY,MBP,KCNIP2,ADCY2,DSCAML1,SORCS1,SCN4B,FGF1,ASIC4,FGR,FHL1,SELL,ANK1,CNIH2,PPFIA1,CACHD1,AQP4,SLC8A3,ASCL1,CGREF1,DLL3,ATP1A2,PALLD,SCN3B,GAD2,B4GALNT1,ADGRB2,NFASC,NCAM1,BCL2L2,GFAP,ADHFE1,ARHGEF7,PCDH11X,GNAS,BTRC,GPR17,HAP1,SYT6,CRB1,TMEM25,FBXL16,ZDHHC22,MAEL,TNFRSF1B,TNS1,ARHGAP19,TPM3,HMGB1,ASIC3,DUSP26,UBTF,CPT1C,NMT2,FTO,PLXNB3,PACSIN1,ATCAY,PPP3CB,NKAIN4,PLCH2,NCAN,CMTM5,NRSN1,PUM1,PROX1,DPYSL5,TOMM20,ZNF385B,SIRPA,JAKMIP2,ELMO1,PRDM2,RGMA,BLOC1S6,PTPRD,KCNJ10,ARNT2,PCDH15,DLG3,WIPF2,PLEKHB2,C12orf4,ATN1,DBX2,DTNA,ABCC9,SIDT2,PIANP,SH3GLB1,CBLN2,ELAVL4,ROM1,EPB41" MicroRNA hsa-miR-222:mirSVR_lowEffct hsa-miR-222:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.67E-35 9.04E-32 2.40E-34 2.20E-33 90 1405 "MAP6,LGR4,MDM4,F3,RTN1,ADD3,KIAA1109,LRRC7,FGF14,ASIC4,BBOX1,MOBP,FOXG1,ERICH3,ASRGL1,USP28,ITSN1,PKP4,NTNG1,GPAM,SLITRK3,ST8SIA1,SHTN1,PAAF1,RPH3A,CGREF1,SLN,ASTN1,SMARCE1,SNAP25,SNCB,USP33,SOX1,IDI2-AS1,NCAM1,RGL1,AJAP1,SLCO1C1,ARHGEF7,PCDH11X,ZNF638,ADGRL3,KLHL4,ANO4,PRUNE2,GPM6B,ATF7,TCF7L2,PTBP2,NUDT21,NUMA1,CRB1,TMEM25,AIFM1,PCDH8,PCDH9,TPM3,TUB,HNRNPK,NRXN1,NEGR1,OPALIN,CNRIP1,MFSD4A,CP,POU3F2,PTPA,PPP2R5C,OSBPL3,ATRNL1,PRKAB2,DOCK7,USP54,CTNND2,NRSN1,RIMS3,ANKS1B,ZNF385B,PMEPA1,LRP8,CEP170,OCIAD1,C1orf109,PTPRZ1,PCDH15,KCNMA1,DLG2,DTNA,SLC6A15,RCAN2" MicroRNA hsa-miR-648:mirSVR_lowEffct hsa-miR-648:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-35 9.23E-32 2.44E-34 2.24E-33 86 1279 "RPL38,MAP6,SYT9,EXTL1,EYA1,WLS,FGF14,ERICH3,PPFIA1,APC,GPAM,TACC2,ST3GAL3,RUFY2,MSR1,ARHGAP5,DACH2,CADPS,ASPH,ASTN1,SNAP25,PALLD,WDTC1,SOX5,CAB39,ZSWIM8,ARPP21,IDI2-AS1,ADAM15,ADGRB2,NFASC,NCAM1,NEUROD1,AJAP1,SEMA4A,TBX15,ATF7,VWC2,CACNB2,GRIA4,GRIK2,OPCML,TGFBR3,TJP1,ZFP91,ARHGAP19,LGI1,TPM4,PCSK2,FNDC5,ACOT7,HPSE2,JAM2,ZFYVE9,NEGR1,FAT3,ACBD5,MED1,MICAL2,FMN2,CTNND1,CTNND2,MASP1,RIMS3,BDNF-AS,PTHLH,PRDM2,PRTFDC1,RGMA,CSDE1,KCNA4,SV2A,RAB5B,KLRC2,RAP1GAP,DSCAM,FAM13C,SLC6A15,CAMK1G,RFX4,SEC61A2,PIANP,RBM12,VWA5A,YY1AP1,UEVLD" MicroRNA hsa-miR-429:PITA hsa-miR-429:PITA_TOP PITA 1.72E-35 9.29E-32 2.45E-34 2.25E-33 70 818 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,SLITRK1,ADD3,NLGN4X,GPR158,TESK2,SCN3A,LRRTM4,FOXG1,ERICH3,SGIP1,ANK3,ITSN1,PPM1E,SLC1A2,RUFY2,SNAP25,MEGF11,SOX1,ZCCHC24,CAB39,NAP1L2,NFASC,NCAM1,CLASP2,RGL1,PHLDB1,NFIA,CAMSAP2,WWC1,GPM6A,CACNB2,ZEB1,CECR2,PSD3,TLL2,CDC42,PCDH8,RBFOX2,ARHGAP19,PCSK2,HMGB1,TMEFF2,NEGR1,ANLN,CCSER2,SLC25A27,BTF3L4,COL9A2,NSD2,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,CTNND2,WBP1L,RIMS3,LRRTM3,PTCH1,ZC3H11A,PTPRZ1,KCNK2,GOPC,PAK5" MicroRNA hsa-miR-30d:mirSVR_highEffct hsa-miR-30d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.77E-35 9.58E-32 2.52E-34 2.31E-33 101 1774 "MAP6,CDHR1,SYT9,RCSD1,ARID1A,CSMD3,GALNT13,CDC7,SORCS1,ERMN,SCN3A,LINC00461,SLC30A10,FOXG1,ERICH3,ITSN1,DOCK10,MAGI3,SORBS1,CACHD1,NLGN1,JAKMIP3,PAAF1,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,SMARCE1,RCOR3,NRG3,ATP2B2,SON,JPH4,KIF1B,NAP1L2,NPAS3,SPART,CLASP2,BCL2L2,RGL1,GLS,GNAS,DDHD2,CAMTA1,ADGRL3,ANO4,PRUNE2,GPM6A,CACNB2,GPR19,EML4,CECR2,GRIA2,RFFL,GRM3,OMG,CRB1,USP2,TLL2,CELF3,PCDH9,LGI1,MAGI1,PIRT,ZMYND8,MS4A7,PIK3CD,MICAL1,ACBD5,PNKD,OSBPL3,PRKACB,DOCK7,CTNND2,TOX,SPIRE1,TOMM20,LRRTM3,CA10,JAKMIP2,CEP170,CSDE1,MAGI2,BLOC1S6,KCNA2,PLPPR4,RABGAP1L,PARP11,RALGDS,PAK5,ABCC9,RGS7,TTLL7,RNF220,RPRD1A,RAVER2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-499-5p:mirSVR_lowEffct hsa-miR-499-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-35 9.62E-32 2.52E-34 2.32E-33 97 1637 "SDE2,ABAT,MBP,LGR4,RTN3,MEG3,ADAR,F3,KLHL32,ADCY2,SLITRK1,ADD3,CDC7,NLGN4X,SOX6,PPFIA1,PPM1E,APC,AQP4,CCDC88A,ASCL1,SPHKAP,ASPH,KBTBD12,MEGF11,SCN3B,USP33,B4GALNT1,SPART,NCAM1,DCAF5,GFRA1,RGL1,NEUROD1,AJAP1,ARHGEF7,ZNF638,CAMTA1,PSRC1,WWC1,TMEM136,PRUNE2,DDR1,TCF12,NUDT21,GRIA2,RFFL,INA,PAX6,IGSF21,PCDH9,DCLK1,PDE1A,PDE3B,ZMYND8,NLGN3,KIAA1549L,NRXN1,SEMA5B,PIK3CD,CCSER2,FTO,CELF5,NXPH1,PPP3CB,RGS6,DZIP3,FMN2,MAPK8,MAPK10,BRINP3,ZBTB16,ANKS1B,SPIRE1,CA10,PTHLH,HP1BP3,MED24,ZC3H11A,KCNA1,OCIAD1,PTPRO,NAV2,DLG2,SLC17A6,DPP6,ABI1,GOPC,DTNA,BSDC1,ZNF248,VANGL2,SEC61A2,LPAR6,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-4290:mirSVR_lowEffct hsa-miR-4290:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-35 1.02E-31 2.67E-34 2.45E-33 92 1472 "CSMD2,HHATL,SORCS1,HOGA1,LRRTM4,SEMA6A,ASIC4,SLC30A10,PDZD4,TRIM46,ANK2,PPFIA1,APBA2,GPAM,ST3GAL3,STK32C,BCO1,SCMH1,NAXD,B3GAT1,NRG3,GABBR1,MYBPC1,WDTC1,CADM3,ADAM15,ALDH1L1,INKA2,KIRREL3,PHLDB1,RND1,FAM168A,ARHGEF7,VAMP1,LUZP2,MYRF,ADGRL3,FAM69C,PCDHGA3,BRSK2,AKNA,GRID1,CRB1,PTPN5,LEFTY2,INA,CD81,TNFRSF1B,TNR,RBFOX2,MAGI1,PIRT,FNDC5,ANO5,LRTM2,CHGA,TLX1,ARHGAP22,NLGN3,SERPINE2,TJP2,FADS2,FLRT1,FTO,MEAF6,CNRIP1,MICAL2,PRKAB2,FMN2,PLPP4,PKN2,USP54,ARHGEF4,WBP1L,PRTFDC1,CDH20,SV2A,KCNJ9,TMCC2,KCNJ11,KCNK2,KCNQ2,WIPF2,ABI1,DTNA,BSDC1,RFX5,PHC2,SH3GLB1,ABI2,EPB41,UEVLD" MicroRNA hsa-miR-544:mirSVR_highEffct hsa-miR-544:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.08E-35 1.13E-31 2.94E-34 2.70E-33 106 1954 "ACER3,MAP6,ACLY,CNTNAP3,ATAT1,CSMD2,SORCS1,AMER2,SLC44A5,KIAA1109,SEMA6A,MOBP,PPFIA1,ITSN1,ANXA7,NTNG1,GPAM,SORBS1,RUFY2,LRRC55,SLCO1A2,ASPH,SMARCE1,ATM,DKK3,MYT1L,TNIK,EMC1,SALL3,NPAS3,RAP1GAP2,NASP,NFASC,CLASP2,RGL1,ARHGEF7,PCDH11X,CAMSAP2,ADGRL3,ANO4,CACNA1A,GPM6B,ZEB1,CAMK2G,GRIA1,GRID1,GPR88,OLR1,CRB1,HPS5,PCDH9,TPD52,PDE1A,PDE3B,CASC2,SERPINE2,CADM1,CAMKV,FLRT1,CCDC136,MEAF6,SPATA6,NSD2,POU3F2,CHD1L,SF1,CRLS1,TENM4,RGS6,KCNT2,ATRNL1,NCAN,RBPJ,PRKACB,DOCK7,DZIP3,FMN2,KIAA1755,CTNND1,TOX,SYTL2,SPIRE1,TOMM20,PLPPR5,ITGAV,BDNF-AS,COPS7A,CSDE1,OLFM3,KCNA4,SMG7,RABGAP1L,KCNK2,KCNMA1,FAM66C,ABI1,DTNA,PAK5,ABCC9,SLC6A15,ZYG11B,RET,RGS7,TTLL7,SYT15,FGFBP3" MicroRNA hsa-miR-3151:mirSVR_lowEffct hsa-miR-3151:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-35 1.16E-31 3.01E-34 2.76E-33 103 1848 "ACER3,ASIC1,SYT9,DUSP27,RCSD1,FAM43B,MRVI1,ATAT1,KCNIP2,SLC25A25,DSCAML1,TUBB4A,FCGR1A,TOMM40L,TESK2,LRRTM4,PLA2G6,SEMA6A,ASIC4,GOLGA7B,HPCAL4,PI16,SH3GL2,PPM1E,ST3GAL3,ZNF365,SLC2A5,PKNOX2,SLC6A9,YPEL4,MT3,SCMH1,TMEM249,GPR153,CSPG5,ASPH,ASTN1,TMEM108,ADGRA1,NRG3,ATP1A3,FYN,MYT1L,SOX10,B4GALNT1,SMOC1,GFAP,ARHGEF7,C1QC,GNAS,NODAL,MYRF,WWC1,TBX15,DDR1,CAMK2A,PCDHGA3,SYT6,NUMA1,GRIK3,CYB561A3,CRB1,TNFRSF1B,ARHGAP19,PCSK2,PDE2A,CHRM1,CASC2,DLGAP3,NRXN2,SEMA5B,NEGR1,CCDC136,COL9A2,PPP3CB,KCNT2,CSF3R,DOCK7,SDC3,KIAA1755,PRKCG,MASP1,WBP1L,DPYSL5,PRTFDC1,ZC3H11A,RABGAP1L,TMCC2,NKAIN1,PLEKHB2,PARP11,DTNA,L1CAM,NUP214,ARHGEF10L,SYT15,SFXN5,SIDT2,PIANP,SLC4A10,ELAVL4,BSCL2,EPB41L2" MicroRNA hsa-miR-4297:mirSVR_lowEffct hsa-miR-4297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-35 1.25E-31 3.24E-34 2.97E-33 95 1575 "RABEPK,MAPT,ACHE,LGR4,ECSIT,KLHL32,GRAMD1B,FCGR1A,DISP3,FGF1,HPCAL4,ERICH3,RASA3,ITSN1,PKP4,NTNG1,ST3GAL3,JAKMIP3,LRRC55,PKNOX2,MT3,NSG2,SCMH1,NAXD,ASPH,PALLD,SON,ILDR2,NMNAT2,KIF1B,NFASC,ALDH1L1,STOX1,NHLH1,DCLK2,NODAL,UNC5D,BTRC,CNTN2,CACNA1E,LRIT2,TCF12,CAMK2A,NUMA1,OPCML,TMEM9,ZDHHC22,PTGDR2,MAGI1,PDE3B,FNDC5,BEST3,PFKFB3,ZBED5,GDAP1L1,NRXN2,UBTF,CPT1C,A2ML1,PLXNB3,BTF3L4,SPATA6,ATCAY,NXPH1,CP,MED1,PNKD,PTPA,SNCAIP,TENM4,FEZ1,MICAL2,ATRNL1,CHD5,PRKAB2,PRKACB,SDC3,PRKCZ,MASP1,ZBTB16,PRDM2,COPS7A,PTPRD,SV2A,KCNJ9,CCDC3,KCNK1,DLG2,NKAIN1,DPP6,DTNA,CAMK1G,ARHGEF10L,ZNF248,PIANP" MicroRNA hsa-miR-1291:mirSVR_lowEffct hsa-miR-1291:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.42E-35 1.31E-31 3.40E-34 3.12E-33 95 1576 "ASIC1,MRVI1,ECSIT,GRAMD1B,NLGN4X,TOMM40L,UNC79,ELMOD1,HPCAL4,MOBP,MOG,SEMA6C,AMPH,ASRGL1,PI16,ITSN1,APBA2,MAGI3,DGKD,BCAN,SORBS1,API5,RPH3A,URGCP,RUFY2,MSR1,ARFGAP2,NSG2,CGREF1,GPR153,SPHKAP,NAXD,BRINP2,TMEM151A,PALLD,WDTC1,NMNAT2,B4GALNT1,TTLL9,ADGRB2,FXYD6,NFASC,BCL2L2,DCAF5,GANAB,SEPT3,ACSBG1,GLS,PCDH11X,UNC5D,KLHL4,LRIT2,TCF7L2,CECR2,BRSK2,CYB561A3,CRB1,LEFTY2,PAX6,TNR,GPR37L1,ADGRG1,GDAP1L1,CAMKV,PACSIN1,PNKD,CRLS1,PTPA,SNCAIP,NKAIN4,FEZ1,RBPJ,SDC3,ARHGEF4,HES5,NOS1AP,KLK6,PHYHIP,PLPPR1,PRDM2,PTPRD,PTPRE,PTPRO,TMCC2,CCDC3,KCNN3,SLC25A48,USH1C,RGR,ARHGEF10L,VANGL2,SIDT2,RBM12,GPR61,RASGRP2" MicroRNA hsa-miR-181a-2*:mirSVR_lowEffct hsa-miR-181a-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-35 1.40E-31 3.61E-34 3.31E-33 102 1817 "PRR5L,MAP6,MAPT,LGR4,ADGRV1,LDLRAD3,ARID1A,WLS,F3,CLIP1,KLHL32,SLITRK1,ADD3,FHL1,SOX6,AMPH,PPFIA1,GPAM,SHTN1,MIER1,SLC1A7,PKNOX2,SLC8A3,SLC14A1,ASCL1,CGREF1,SCG3,NAXD,ASPH,SORCS3,SMARCE1,TMEM108,CCDC181,EIF4G3,FYN,USP33,SON,KIF21B,ZSWIM8,ARPP21,TTLL9,RAP1GAP2,NASP,NCAM1,CLASP2,GLS,VAMP1,DDHD2,CAMTA1,NODAL,MMD2,BTRC,ADGRL3,TBX15,GPM6A,GPM6B,CACNB2,TCF7L2,HAP1,CAMK2A,CRB1,USP2,INA,AIFM1,PCDH8,PCDH9,DCLK1,TPD52,FNDC5,ASIC3,HPCA,SERPINE2,CADM1,NMT2,CCSER2,BEST1,PRRX1,CNRIP1,RGS6,DOCK7,DZIP3,FMN2,MAPK10,CA10,PRDM2,CSDE1,KCNA4,PTPRO,KCNJ10,KCNK2,PCDH15,PARP11,RAP1GAP,ABCC9,SLC6A15,NUP214,RFX4,ATL1,VANGL2,PIANP,ABI2,YY1AP1" MicroRNA hsa-miR-194:mirSVR_lowEffct hsa-miR-194:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.93E-35 1.59E-31 4.09E-34 3.76E-33 105 1926 "ACER3,CDHR1,MBP,LGR4,EYA1,ADCY2,ERMN,AMER2,SLC44A5,GPR158,HOGA1,LINC00461,SOX6,SELL,ERICH3,SH3GL2,SYBU,ST3GAL3,ARHGAP5,SLC8A3,SHANK2,SLC14A1,SLIT1,CAPRIN2,ASPH,MEGF11,DKK3,KIF21B,KIF1B,CPLX2,NPAS3,C11orf87,NDUFA5,GJB1,RND1,MLC1,ZNF638,KAZN,MMD2,GPM6B,LILRA1,TCF7L2,ZEB1,PTBP2,EML4,CAMK2G,AKNA,GRIK2,GRM3,OLR1,TGFBR3,TJP1,TMEM257,MAEL,PCSK2,PDE3B,HMGB1,CASC2,JAM2,CADM1,KIAA1549L,NEGR1,ANLN,OPALIN,CELF5,COL9A2,NSD2,NXPH1,CHD1L,MED1,SF1,CRLS1,KCNT2,OSBPL3,PHACTR3,DZIP3,RAB39A,TOX,WBP1L,PLPPR5,PTCH1,DNAJC6,ITGAV,CA10,PMEPA1,PRDM2,KCNA4,PTPRO,C1orf109,RABGAP1L,KCNJ10,KCNK1,KCNK2,DNM2,SLC17A6,PLEKHB2,RALGDS,ATG16L1,ABI1,BSDC1,JMJD1C,ATL1,RBM12,RPRD1A,EPB41L2" MicroRNA hsa-miR-920:mirSVR_lowEffct hsa-miR-920:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-35 1.66E-31 4.27E-34 3.92E-33 105 1927 "ABAT,ASIC1,ACHE,MRVI1,ATAT1,CSMD2,MDM4,F3,KLHL32,SLITRK1,RXRG,SORCS1,GRAMD1B,HOGA1,LRRTM4,ASIC4,SOX6,FOXM1,TRIM46,USP28,NTNG1,SORBS1,SYBU,ST3GAL3,ST8SIA1,SHTN1,SLC7A14,RPH3A,SFMBT2,SLC2A5,RUFY2,SLC8A2,NSG2,ADGRA1,WDTC1,SOX10,ARPP21,IDI2-AS1,ADAM15,CPLX2,LMO3,ALDH1L1,NELL1,KIRREL3,RHBDL3,CASTOR3,GPM6A,ATF7,NEU4,TCF7L2,ZEB1,NRGN,HAP1,CAMK2A,PCDHGA3,TMEM151B,BRSK2,GRIA2,ATP13A2,TIE1,TMEM9,TLL2,PTGDR2,TPM3,PIRT,CHRM1,PLEKHB1,CASC2,NLGN3,ST8SIA5,FLRT1,FTO,PLXNB3,CABP1,MFSD4A,CHD1L,SNCAIP,NKAIN4,PRKCZ,NRSN1,WBP1L,ZNF385B,PTCH1,HP1BP3,KCNA6,KCNJ9,DLG2,KLRC2,SLC25A48,SUSD4,L1CAM,FAM135B,SFXN5,SIDT2,CACNG7,PIANP,RBM12,RPRD1A,ABI2,VWA5A,YY1AP1,EN2,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-155:mirSVR_highEffct hsa-miR-155:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.13E-35 1.69E-31 4.34E-34 3.98E-33 91 1449 "SDE2,ABAT,ACTN2,EYA1,CSMD3,ADD3,ERMN,SCN3A,LRRTM4,KIAA1109,LRRC7,FGF14,FHL1,ELMOD1,SGIP1,ANK3,PPFIA1,ITSN1,SH3GL2,MAGI3,NLGN1,SHTN1,PAAF1,MIER1,RUFY2,NSG2,ASPH,SNAP25,NRG3,PALLD,SOX1,B3GALT2,KIF21B,CAB39,ARPP21,NAP1L2,SPART,NCAM1,STOX1,RGL1,CASTOR3,ZNF638,DCLK2,GNAS,CAMTA1,ADGRL3,WWC1,KLHL4,GPM6A,GPM6B,TCF7L2,TCF12,PTBP2,INA,PCDH9,HPSE2,CASC2,NRXN1,NEGR1,NMT2,CNTN1,PRRX1,MFSD4A,CRLS1,MICAL2,PRKACB,PKN2,CTNND1,PUM1,TOX,PRTFDC1,CSDE1,OLFM3,PTPRD,KCNMA1,DLG2,KLRC3,PLEKHB2,DTNA,PAK5,L1CAM,BSDC1,ABCC9,SLC6A15,ZYG11B,RNF220,SSPN,LPAR6,SLC4A10,C2orf80,EN2" MicroRNA hsa-miR-625:mirSVR_lowEffct hsa-miR-625:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.34E-35 1.81E-31 4.63E-34 4.25E-33 94 1549 "TTYH1,ACER3,MAPT,MRVI1,CSMD2,ADAR,AMER2,NLGN4X,CHST15,TOMM40L,UNC79,MOBP,SOX6,SEMA6C,SORBS1,ARHGAP5,ARFGAP2,DACH2,SLCO1A2,SLIT1,SLN,SORCS3,RCOR3,B3GAT1,PHYHIPL,MYT1L,SOX10,ZSWIM8,TTC9B,CPLX2,NFIA,ARHGEF7,VAMP1,RHBDL3,DCLK2,GNAS,ROBO3,CDK5R2,WSCD1,ATF7,AZIN2,PTBP2,VSTM2A,AKNA,GRIA1,ADAMTS8,CYB561A3,LINC00839,USP2,ZDHHC22,ZFP91,PAX6,IGSF21,RBFOX2,LGI1,FNDC5,PFKFB3,CASC2,DLGAP3,NRXN1,NEGR1,FTO,PLXNB3,MEAF6,PRRX1,NSD2,PNKD,CSF3R,ATRNL1,SDC3,IGSF1,KIAA0513,WBP1L,PHYHIP,PMEPA1,PTHLH,CNIH3,PRDM2,PRTFDC1,LRP8,CSDE1,BLOC1S6,KCNA1,KCNJ4,ARNT2,KCNK2,PCDH15,NAV2,RAB3IL1,DPP6,PHC2,ABI2,CBLN2,EPB41L1" MicroRNA hsa-miR-125a-5p:mirSVR_lowEffct hsa-miR-125a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.55E-35 1.92E-31 4.90E-34 4.50E-33 93 1517 "ABAT,MAP6,ACHE,EMID1,MEG3,PLEKHG5,ERMN,FCGR1A,SNX32,ASIC4,MOBP,PI16,ITSN1,PKP4,APC,MAGI3,DGKZ,API5,ARFGAP2,DACH2,GPR153,SLCO1A2,LGI3,C10orf105,NRG3,WDTC1,MYT1L,KIF21B,ENKUR,B4GALNT1,NFASC,NCDN,ADHFE1,FAM168A,GLS,ZNF638,GNAS,GOLGB1,TMEM136,CACNA1E,DDR1,DIRAS1,CECR2,GRIA2,TF,CRB1,PADI2,DCLK1,PTGDR2,HRH3,PDE3B,CASC2,KIAA1549L,NRXN1,CAMKV,OPALIN,FADS2,MFSD4A,POU3F2,PTPA,PPP2R5C,TENM4,NCAN,CMTM5,PRKCZ,MAPK10,FAM131B,ECE2,NOS1AP,PROX1,PSMD13,CNIH3,PRDM2,COPS7A,CSDE1,ZC3H11A,KCNA1,PTPRD,PTPRE,C1orf109,SV2A,PCDH15,CAB39L,WIPF2,PARP11,GOPC,DTNA,SLC6A15,RET,FAM135B,PHC2,ZNF248,SYT15" MicroRNA hsa-miR-4300:mirSVR_lowEffct hsa-miR-4300:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.63E-35 1.96E-31 5.00E-34 4.59E-33 85 1261 "ASIC1,ACHE,ATAT1,KLHL32,SLITRK1,SORCS1,GRAMD1B,LRRTM4,ASIC4,SOX6,FOXM1,TRIM46,USP28,NTNG1,SORBS1,SYBU,ST3GAL3,ST8SIA1,MIER1,SLC7A14,RPH3A,SFMBT2,SLC8A2,CGREF1,WDTC1,SOX10,ARPP21,IDI2-AS1,ADAM15,CPLX2,LMO3,BCL2L2,ALDH1L1,NELL1,RHBDL3,CASTOR3,LUZP2,GPM6A,NEU4,TCF7L2,ZEB1,HAP1,PCDHGA3,BRSK2,GRIA2,ATP13A2,PTPN5,TIE1,TMEM9,TLL2,PTGDR2,PIRT,CHRM1,PLEKHB1,CASC2,NLGN3,ST8SIA5,FLRT1,PLXNB3,CABP1,MFSD4A,CHD1L,SNCAIP,NKAIN4,NCAN,PRKCZ,WBP1L,ZNF385B,KCNA6,DLG2,KLRC2,SLC25A48,PLEKHB2,SUSD4,SIDT2,CACNG7,RBM12,RPRD1A,ABI2,VWA5A,YY1AP1,EN2,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-493-5p:TargetScan hsa-miR-493-5p TargetScan 4.09E-35 2.21E-31 5.62E-34 5.15E-33 60 580 "ADARB2,GRAMD1B,ANK2,DGKD,NLGN1,CLSTN1,MADD,LRRC55,ARHGAP5,NSG2,IGSF9B,MYT1L,NMNAT2,KIF1B,GART,CPLX2,NPAS3,LMO3,KAZN,CAMSAP2,ANO4,CACNB2,NUDT21,PSD3,OPCML,PDE1C,GPR37L1,NLGN3,NEGR1,FTO,FAT3,MED1,PPP2R5C,PPP3CB,IGSF1,CTNND1,CTNND2,KIAA0408,RIMS3,LRRTM3,PTCH1,JAKMIP2,CADM2,ELMO1,HP1BP3,PTPRD,KCND3,AK5,KCNJ10,KCNK1,NAV2,DLG2,KIF2A,RAD52,L1CAM,RGS10,EFNA3,RBM12,ABI2,ARHGAP12" MicroRNA hsa-miR-548k:mirSVR_highEffct hsa-miR-548k:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-35 2.30E-31 5.83E-34 5.35E-33 98 1689 "RBM10,SYT9,RTN3,MEG3,F3,RTN1,ADCY2,CHST15,LRRC7,MOG,AMPH,PPFIA1,ANXA7,MAGI3,API5,PAAF1,USP16,ZNF365,MIER1,LRRC55,CCDC88A,CSPG5,ASPH,SMARCE1,RCOR3,SNAP25,CCDC181,PALLD,MYT1L,ARPP21,NEK6,FXYD6,NPAS3,C11orf87,CLASP2,DCAF5,ARHGEF7,ZNF638,SYT4,LUZP2,CAMTA1,CAMSAP2,ADGRL3,PRUNE2,GPM6A,VWC2,ZEB1,GRIA2,GRIA4,CRB1,TMEM257,MAEL,LGI1,PDE3B,PDE4B,JAM2,NRXN1,CCSER2,TJP2,CNTN1,CELF5,SLC25A27,IFFO1,NXPH1,CP,SF1,PPP2R5C,TENM4,PPP3CB,FEZ2,VCAN,RBPJ,PRKACB,CTNND1,PROX1,MASP1,PLPPR5,COPS7A,ZC3H11A,PLPPR4,PTPRZ1,KCNK2,NAV2,DLG2,PLEKHB2,SLC25A18,FAM13C,PAK5,SLC6A15,RFX4,JMJD1C,INSYN2,RPRD1A,FGFBP3,ARHGAP12,CBLN2,ELAVL3,TMEM100" MicroRNA hsa-miR-137:mirSVR_lowEffct hsa-miR-137:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.49E-35 2.43E-31 6.14E-34 5.63E-33 96 1622 "ACTN2,CSMD2,NLGN4X,GPR158,TESK2,FGF1,SOX6,SGIP1,ANK3,USP28,PPM1E,DOCK10,MAGI3,GPAM,NLGN1,ST3GAL3,API5,ARHGAP5,SCG3,LGI3,CAPRIN2,SORCS3,RCOR3,FYN,SON,SOX5,NAP1L2,NPAS3,NFASC,DCAF5,HEPN1,SEPT3,FAM168A,MLC1,POPDC3,DDHD2,TBX15,PRUNE2,CACNB2,TCF7L2,NRDC,VSTM2A,GRM3,OPCML,CRB1,GUCY1A2,GUCY1A1,PAH,CDC42,PCDH8,PCDH9,PDE3B,TMEFF2,NEGR1,NMT2,CCSER2,DNAJC12,POU3F2,PPP2R5C,OSBPL3,ATRNL1,RIMS4,FMN2,CTNND1,NRSN1,FGFR1OP2,RIMS3,GON4L,ITGAV,JAKMIP2,LRP8,KCNA1,OLFM3,CDH20,PTPRO,SV2A,SRGAP3,KCNK1,KCNK2,PCDH15,PID1,RAD52,FAM66C,C12orf4,ABI1,RASGRF1,SLC6A15,RGS7,INSYN2,ATL1,TTLL7,RLBP1,EFNA3,ABI2,SLC4A10,ELAVL4" MicroRNA hsa-miR-92b:mirSVR_lowEffct hsa-miR-92b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.72E-35 2.55E-31 6.43E-34 5.90E-33 96 1623 "EPS8,C1orf194,ACER3,RBM10,LGR4,SYNDIG1,ADARB2,ADD3,GPR158,TESK2,LINC00461,FGF1,BCAR3,UNC79,FOXG1,AMPH,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,SORCS3,ASTN1,ATP1A2,GABBR1,MYT1L,AHCYL1,ENKUR,NAP1L2,ERBIN,NEUROD1,NFIA,GLS,ZNF638,NKX2-2,DDHD2,NODAL,CDK5R2,BTRC,KLHL4,TBX15,GPM6B,ZEB1,EML4,VSTM2A,GRIA4,GRIK2,TMEM257,CDC42,PCDH8,PCDH9,LGI1,PIRT,PDYN,CHGA,CASC2,JAM2,CADM1,KIAA1549L,BTF3L4,SPATA6,CHD1L,CRLS1,PPP2R5C,PPP3CB,NKAIN4,MICAL2,PHACTR3,PRKACB,DZIP3,PRKCG,PKN2,ECE2,NOS1AP,ZNF385B,SIRPA,PMEPA1,PRDM2,HP1BP3,KCNA1,OCIAD1,NTM,KCNMA1,SLC25A48,C12orf4,ABI1,SLC6A15,JMJD1C,INSYN2,RLBP1,RERGL,ABI2,FGFBP3" MicroRNA hsa-miR-15b:PITA hsa-miR-15b:PITA_TOP PITA 5.27E-35 2.85E-31 7.10E-34 6.51E-33 67 754 "RTN3,SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-497:PITA hsa-miR-497:PITA_TOP PITA 5.27E-35 2.85E-31 7.10E-34 6.51E-33 67 754 "RTN3,SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-195:PITA hsa-miR-195:PITA_TOP PITA 5.27E-35 2.85E-31 7.10E-34 6.51E-33 67 754 "RTN3,SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-15a:PITA hsa-miR-15a:PITA_TOP PITA 5.27E-35 2.85E-31 7.10E-34 6.51E-33 67 754 "RTN3,SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-16:PITA hsa-miR-16:PITA_TOP PITA 5.27E-35 2.85E-31 7.10E-34 6.51E-33 67 754 "RTN3,SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-92a:mirSVR_lowEffct hsa-miR-92a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-35 2.96E-31 7.35E-34 6.74E-33 97 1660 "EPS8,C1orf194,ACER3,RBM10,LGR4,SYNDIG1,ADARB2,ADD3,GPR158,TESK2,LINC00461,FGF1,BCAR3,UNC79,FOXG1,AMPH,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,SORCS3,ASTN1,GABBR1,MYT1L,AHCYL1,ENKUR,NAP1L2,ERBIN,NEUROD1,NFIA,GLS,ZNF638,NKX2-2,DDHD2,NODAL,CDK5R2,BTRC,KLHL4,TBX15,GPM6B,ZEB1,EML4,GRIA4,GRIK2,TMEM257,CDC42,PCDH8,PCDH9,LGI1,PIRT,PDYN,HMGB1,CHGA,CASC2,JAM2,CADM1,KIAA1549L,BTF3L4,SPATA6,CHD1L,CRLS1,PPP2R5C,PPP3CB,NKAIN4,PHACTR3,PRKAB2,PRKACB,DZIP3,PRKCG,PKN2,ECE2,NOS1AP,ZNF385B,SIRPA,PMEPA1,PRDM2,HP1BP3,KCNA1,OCIAD1,NTM,KCNMA1,SLC25A48,C12orf4,ABI1,SLC6A15,RET,JMJD1C,INSYN2,RLBP1,RERGL,ABI2,FGFBP3,EPB41L2" MicroRNA hsa-miR-1245:mirSVR_lowEffct hsa-miR-1245:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.85E-35 3.17E-31 7.85E-34 7.20E-33 89 1396 "SYT9,EYA1,FABP7,FCGR1A,CHST15,HOGA1,FGF1,SEMA6A,MOG,SOX6,ERICH3,PPFIA1,APBB1,GPAM,SLITRK3,NLGN1,SHTN1,ZNF365,SLC8A3,SHANK2,CGREF1,SPHKAP,SMARCE1,RCOR3,ATM,B3GALT2,KIF21B,ZSWIM8,JPH4,B4GALNT1,ARPP21,ADAM15,CLASP2,DCAF5,SLCO1C1,ARHGEF7,ABCC8,PCDH11X,C1QC,NODAL,CDK5R2,UNC5D,CACNB2,ZEB1,DIRAS1,PTBP2,NUDT21,VSTM2A,AKNA,GRIA1,GRIA4,KCNK10,MAEL,PAX6,PCDH9,CDH8,CDH10,TPM4,CA14,NLGN3,OPALIN,PRRX1,ATCAY,NXPH1,CRMP1,PTPA,SNCAIP,TENM4,OSBPL3,MASP1,TOMM20,KCNA1,KCNK2,PCDH15,WIPF2,SLC17A6,PARP11,RASGRF1,PAK5,ABCC9,ZYG11B,NUP214,RFX4,ATL1,SSPN,RBM12,SH3GLB1,EN2,TMEM100" MicroRNA hsa-miR-550:mirSVR_lowEffct hsa-miR-550:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.79E-35 3.68E-31 9.08E-34 8.33E-33 101 1803 "ZFYVE27,MAPT,ACLY,EYA1,MRVI1,LDLRAD3,DSCAML1,DRAXIN,BCAR3,ANK1,USP28,ITSN1,APBA2,APBB1,DGKD,ST3GAL3,SHTN1,SFMBT2,LRRC55,SLC6A9,YPEL4,MT3,NSG2,DACH2,CGREF1,NAXD,B3GAT1,NRG3,USP33,B3GALT2,ZSWIM8,NMNAT2,SALL3,TTLL9,IDI2-AS1,ADAM15,NAP1L2,FXYD6,NPAS3,NFASC,CLASP2,NDUFA5,STOX1,DCAF5,INKA2,KIRREL3,ACSBG1,ZNF638,SEMA4A,CAMTA1,CNDP1,NRGN,AZIN2,TMEM151B,GRIA4,OPCML,LINC00839,TGFBR3,MFSD2A,PTGDR2,MAGI1,PDE2A,LINC01102,PDYN,CHGA,MS4A7,UBTF,CPT1C,A2ML1,FADS2,BEST1,NSD2,NXPH1,NCAN,IGSF1,WBP1L,DPYSL5,PHYHIP,BDNF-AS,ELMO1,LRP8,STMN4,SMG7,PTPRE,NTM,AK5,KCNJ11,PCDH15,CAB39L,RAB5B,TMEM255A,RALGDS,C12orf4,GNE,L1CAM,SLC6A15,SSPN,RBM12,ABI2,ARHGAP12,EPB41L2" MicroRNA hsa-miR-620:mirSVR_lowEffct hsa-miR-620:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.67E-35 4.15E-31 1.02E-33 9.38E-33 97 1667 "SERPINA3,DUSP27,MRVI1,WLS,MDM4,SCN4B,LINC00461,SEMA6A,MOG,SOX6,ANK2,SORBS1,CACHD1,JAKMIP3,SHTN1,PAAF1,SFMBT2,ARHGAP5,SLC8A3,ASPH,ASTN1,ATM,EIF4G3,ATP2B2,KIF21B,CAB39,ADAM15,KIF1B,NCAM1,NDUFA5,INKA2,RGL1,NEUROD1,ACSBG1,GLS,DCLK2,CDK5R2,WWC1,KLHL4,PRUNE2,LRIT2,CACNB2,PTBP2,TMEM151B,VXN,OLR1,GUCY1A1,TMEM257,KCNK10,DAAM2,MAEL,REPS2,IGSF21,PDE1C,PDE3B,LINC01102,FNDC5,PFKFB3,TMEFF2,HEPACAM,NLGN3,CCSER2,VAV2,SF1,PTPA,PPP2R5C,SNCAIP,CSF3R,ATRNL1,FMN2,KIAA1755,CTNND1,MASP1,SPIRE1,PSMD13,CEP170,CSDE1,MAGI2,BLOC1S6,CDH20,OCIAD1,SMG7,NTM,KCNJ9,ARNT2,SNX27,DLG2,RAB5B,FAM66C,RALGDS,NUP214,FAM135B,INSYN2,ARHGEF10L,PHC2,VANGL2,UEVLD" MicroRNA hsa-miR-218-2*:mirSVR_lowEffct hsa-miR-218-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.55E-35 4.63E-31 1.14E-33 1.04E-32 100 1773 "ASIC1,SRARP,SYT9,DUSP27,ADGRV1,MRVI1,CSMD2,RTKN,SORCS1,AGT,LRRC7,ELMOD1,MOBP,ANK3,ITSN1,PPM1E,NLGN1,BCAS1,PKNOX2,SLC8A3,DACH2,CADPS,CSPG5,ATM,PALLD,SON,TTLL9,KIF1B,SPART,DCAF5,NEUROD1,GANAB,SEPT3,RHBDL3,ZNF638,DDHD2,CAMTA1,TBX15,ATF7,TCF12,HAP1,PCDHGA3,VSTM2A,GRIA4,GRID1,GRIK3,TJP1,TMEM257,CDK11B,PAX6,CDC42,ARHGAP19,TPD52,ZNF384,LINC01102,NTSR2,PFKFB3,CASC2,TLX1,NRXN1,PLXNB3,PMP2,SPATA6,NSD2,KCNT2,FEZ2,FEZ1,ATRNL1,RBPJ,PRKACB,FMN2,PKN2,USP54,PUM1,KIAA0408,PLPPR1,JAKMIP2,PMEPA1,ITIH2,CEP170,CSDE1,PTPRD,KCNJ10,CCDC3,KCNK1,KCNK2,DLG2,PARP11,RALGDS,ABI1,DTNA,PAK5,FAM135B,TTLL7,RNF220,SLC4A10,ELAVL3,ELAVL4,TMEM100,EPB41L1" MicroRNA hsa-miR-183*:mirSVR_highEffct hsa-miR-183*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.86E-35 4.80E-31 1.18E-33 1.08E-32 97 1670 "ACER3,SYT9,LGR4,ARID1A,ADCY2,ADD3,SLC44A5,SCN3A,KIAA1109,LRRC7,ELMOD1,HPCAL4,MOBP,AMPH,ANK2,TACC2,NLGN1,BCAS1,SHTN1,AQP4,MIER1,RUFY2,MSR1,ARHGAP5,CCDC88A,DACH2,SLCO1A2,ASPH,SLN,SMARCE1,RCOR3,PHYHIPL,B3GALT2,SOX5,CAB39,ENKUR,CLASP2,STOX1,ADHFE1,NEUROD1,ACSBG1,PCDH11X,ZNF638,LUZP2,CAMTA1,ADGRL3,TMEM136,TBX15,PRUNE2,LILRA1,VSTM2A,GRIA1,GRIA4,GRIK3,TMEM25,TJP1,HPS5,CDC42,LGI1,PDE4B,HMGB1,SCRG1,ANO5,CASC2,NRXN1,DNAJC12,SLC25A27,SPATA6,NSD2,PPP2R5C,SNCAIP,PPP3CB,KCNT2,ATRNL1,VCAN,NCAN,PKN2,IGSF1,ZBTB16,LRRTM3,DNAJC6,CADM2,HP1BP3,CEP170,MAGI2,OLFM3,PTPRO,RABGAP1L,KCNK2,PCDH15,RAB5B,PID1,DPP6,RFX5,INSYN2,SLC4A10,ELAVL4" MicroRNA hsa-miR-103-2*:mirSVR_highEffct hsa-miR-103-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.28E-35 5.02E-31 1.23E-33 1.13E-32 90 1437 "EPS8,ACER3,ACLY,LGR4,ATAT1,ADAR,KLHL32,TMEM156,LINC00461,FGF1,FHL1,UNC79,MOBP,ANK2,ANK3,PPFIA1,ITSN1,SH3GL2,APBA2,MAGI3,SORBS1,SYBU,API5,ARHGAP5,CCDC88A,DACH2,SLCO1A2,RCOR3,TMEM108,SON,CAB39,SALL3,NAP1L2,SPART,CLASP2,RGL1,GLS,ZNF638,KAZN,ANO4,VXN,NUMA1,GRIA2,GRIN1,ZFP91,HPS5,CDH8,CDH10,RBFOX2,SEZ6L,LGI1,MAGI1,PFKFB3,NRXN1,NEGR1,TJP2,P2RY12,CHD1L,PPP2R5C,FEZ2,OSBPL3,PLCH2,DZIP3,CTNND2,RIMS3,SYTL2,PLPPR5,TUBB2B,LRRTM3,PRTFDC1,HP1BP3,CEP170,MAGI2,STMN4,KCNA1,PTPRE,KCNC1,RABGAP1L,KCNK1,KCNK2,PCDH15,SLC17A6,FAM13C,DTNA,ABCC9,RFX4,ZNF248,RBM12,SLC4A10,EPB41" MicroRNA hsa-miR-217:mirSVR_highEffct hsa-miR-217:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.63E-35 5.22E-31 1.27E-33 1.17E-32 85 1278 "ACER3,ADGRV1,ATAT1,CSMD3,RTN1,GALNT13,CHST15,TOMM40L,LRRTM4,LRRC7,ELMOD1,SFPQ,CDC42BPA,ANK3,PKP4,DOCK10,NTNG1,CCDC80,SLITRK3,TACC2,SORBS1,CACHD1,ZNF365,SFMBT2,BCO1,RUFY2,SLC14A1,DACH2,ASPH,SORCS3,ATM,TMEM151A,B3GALT2,NAP1L2,NPAS3,ZNF302,NEUROD1,AJAP1,GLS,UNC5D,ADGRL3,GPM6A,CACNA1E,ZEB1,AKNA,GRIA2,GRIK2,PCDH8,PCDH9,PDE4B,BEST3,TMPRSS5,CASC2,NEGR1,ANLN,TJP2,MEAF6,SLC25A27,SPATA6,MFSD4A,MED1,SF1,ATRNL1,DOCK7,PKN2,NRSN1,EDRF1,KIAA0408,TOMM20,PTCH1,ITGAV,CNIH3,COPS7A,SV2A,RABGAP1L,PCDH15,KCNMA1,SNX27,C12orf4,GOPC,ABCC9,SYT15,SEC61A2,SLC39A12,RPRD1A" MicroRNA hsa-miR-374a*:mirSVR_highEffct hsa-miR-374a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.85E-35 5.33E-31 1.30E-33 1.19E-32 93 1537 "ACER3,LGR4,RTN3,ADGRV1,ATAT1,ARID1A,MDM4,ERMN,AMER2,SCN3A,LRRC7,SEMA6A,ELMOD1,ERICH3,ANK3,APC,NTNG1,NLGN1,BCAS1,API5,CCDC88A,SHANK2,DACH2,SLCO1A2,SPHKAP,ASPH,SMARCE1,SNAP25,PALLD,SON,SOX5,CAB39,ENKUR,C11orf87,DCAF5,RGL1,SLCO1C1,PCDH11X,ZNF638,GNAS,DDHD2,TCF7L2,ZEB1,NUDT21,VSTM2A,GRIA1,GPR88,TF,P2RX7,TJP1,ZDHHC22,PAH,MAEL,PAX6,HPS5,CDC42,C1orf94,MAGI1,PDE3B,PDE4B,ZBED5,SPATA6,ACBD5,CRLS1,SNCAIP,PPP3CB,RBPJ,PLD5,CTNND1,WBP1L,ANKS1B,PLPPR5,ITGAV,JAKMIP2,PTHLH,CADM2,PRDM2,PLPPR4,PTPRO,AK5,PCDH15,CAB39L,TMEM255A,SLC17A6,DPP6,GOPC,L1CAM,TTLL7,SYT15,ABI2,RAVER2,EN2,RCAN2" MicroRNA hsa-miR-3140:mirSVR_highEffct hsa-miR-3140:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-34 5.49E-31 1.33E-33 1.22E-32 88 1374 "MBP,SYT9,EYA1,ATAT1,RTKN,CLIP1,ADD3,FGF1,ELMOD1,PPM1E,DOCK10,ZCCHC17,AQP4,ZNF365,MIER1,NAXD,SMARCE1,NRG3,PALLD,USP33,SON,MYT1L,ARPP21,EMC1,TTLL9,NCAM1,ALDH1L1,NEUROD1,ARHGEF7,CASTOR3,ZNF638,GNAS,CAMTA1,ADGRL3,ANO4,TCF7L2,PTBP2,CAMK2G,GRIA2,GRM3,OPCML,TJP1,AIFM1,TMEM257,ZFP91,REPS2,C1orf94,PCDH9,LGI1,MAGI1,PDE1A,PDE3B,PDE4B,CASC2,HERC2P3,TMEFF2,NEGR1,TJP2,MEAF6,CELF5,BEST1,P2RY12,FAT3,CRMP1,CRLS1,OSBPL3,ATRNL1,VCAN,RBPJ,SDC3,PKN2,DNAJC6,JAKMIP2,PRTFDC1,MAGI2,KCNK1,KCNK2,KCNMA1,CAB39L,HS3ST4,DNAH9,SLC17A6,C12orf4,PAK5,INSYN2,RBM12,RPRD1A,EPB41L1" MicroRNA hsa-miR-888:mirSVR_highEffct hsa-miR-888:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-34 5.57E-31 1.35E-33 1.24E-32 95 1605 "ACER3,DUSP27,RCSD1,ADGRV1,CSMD2,WLS,RTN1,RXRG,ADD3,CDC7,SORCS1,ERMN,ADORA3,SLC44A5,TESK2,FGF14,ELMOD1,FOXG1,CDC42BPA,FOLH1,ITSN1,SESN3,GPAM,SYBU,API5,PAAF1,MIER1,RUFY2,ASPH,SMARCE1,DKK3,USP33,ZCCHC24,AHCYL1,NMNAT2,ARPP21,KIF1B,DNER,SPART,LMO3,CLASP2,NDUFA5,ERBIN,GLS,VAMP1,SYT4,DCLK2,CAMTA1,ADGRL3,LILRA1,VSTM2A,GRIA2,OLR1,CDC42,LGI1,MAGI1,MEAF6,CELF5,SLC25A27,CP,MED1,PPP2R5C,KCNT2,FEZ1,RBPJ,PRKACB,DOCK7,PKN2,PRKCZ,IGSF1,EDRF1,LRRTM3,HP1BP3,LRP8,MAGI2,KCNA4,PLPPR4,PTPRO,KCNK2,NAV2,GOPC,FAM13C,PAK5,SLC6A15,RGR,JMJD1C,FAM135B,ZNF248,SEC61A2,SLC39A12,SSPN,RPRD1A,C2orf80,EN2,UEVLD" MicroRNA hsa-miR-1255a:mirSVR_lowEffct hsa-miR-1255a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-34 5.98E-31 1.44E-33 1.32E-32 98 1709 "ABAT,ASIC1,MAPT,CDHR1,SYT9,RCSD1,ACTN2,ADGRV1,ATAT1,LDLRAD3,KCNIP2,KLRC4,CDC7,GRAMD1B,TOMM40L,LRRC7,FGR,SOX6,USP28,PKP4,DGKZ,LRRC55,DLL3,NAXD,MTR,SORCS3,SNAP25,ATM,WDTC1,B3GALT2,ZCCHC24,SOX10,ENKUR,JPH4,TTLL9,KIF1B,FXYD6,RAP1GAP2,C11orf87,STOX1,GPR162,GFAP,NEUROD1,ARHGEF7,GNG3,ANO4,GPM6A,CACNA1E,ZEB1,NUDT21,CRB1,ZFP91,DAAM2,PCDH9,HMGB1,TLX1,JAM2,HEPACAM,SEMA5B,CPT1C,OPALIN,TJP2,VAV2,BEST1,BTF3L4,IFFO1,NSD2,CNRIP1,CHD1L,PTPA,PPP2R5C,PRKACB,CMTM5,PRKCZ,USP54,NRSN1,FAM131B,MASP1,PTHLH,LRP8,OCIAD1,PTPRD,KCNJ11,KCNK1,PCDH15,PEX5,RALGDS,C12orf4,FAM13C,DTNA,ABCC9,INSYN2,ARHGEF10L,SYT15,RPRD1A,ABI2,OLIG2,EPB41L1" MicroRNA hsa-miR-522:mirSVR_highEffct hsa-miR-522:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-34 6.10E-31 1.47E-33 1.35E-32 97 1675 "SDE2,ACER3,CDHR1,RTN3,ADGRV1,SLC25A25,CLIP1,CHST15,GPR158,BCAR3,CDC42BPA,RASA3,PKP4,PPM1E,DOCK10,DGKD,BCAS1,RPH3A,RUFY2,ARHGAP5,CCDC88A,ASCL1,CSPG5,SMARCE1,RCOR3,SNAP25,NRG3,PHYHIPL,WDTC1,B3GALT2,AHCYL1,NMNAT2,NAP1L2,NCAM1,LMO3,NDUFA5,NEUROD1,RND1,GLS,ZNF638,CAMTA1,PRUNE2,GPM6A,GPM6B,CECR2,VXN,GRIA1,GPR88,TJP1,TMEM257,ZFP91,PADI2,LGI1,TPM3,ZNF384,PDE3B,LINC01102,BEST3,HNRNPK,TLX1,CADM1,A2ML1,FLRT1,CNTN1,CELF5,PRRX1,SPATA6,ACBD5,SNCAIP,KCNT2,VCAN,RBPJ,PRKACB,DOCK7,USP54,FGFR1OP2,SYNC,LRP8,CSDE1,ZC3H11A,PTPRE,KCNK2,KCNN3,DLG2,KLRC3,ABI1,RASGRF1,FAM13C,DTNA,PAK5,ABCC9,SLC6A15,JMJD1C,RBM12,ABI2,RAVER2,EPB41L2" MicroRNA hsa-miR-575:mirSVR_lowEffct hsa-miR-575:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-34 6.12E-31 1.47E-33 1.35E-32 88 1376 "TTYH1,ACER3,CDHR1,RTN3,MRVI1,LDLRAD3,RTKN,ADCY2,CDC7,SORCS1,SCN3A,HPCAL4,SELL,RASA3,CNIH2,MAGI3,CACHD1,SLC2A5,NSG2,SPHKAP,SMARCE1,RCOR3,IGSF9B,DKK3,SON,B4GALNT1,CLASP2,ACSBG1,MLC1,DCLK2,DDHD2,MYRF,TBX15,NEU4,CACNB2,HAP1,CAMK2A,CECR2,GRIA1,ATP13A2,OPCML,LINC00839,MAEL,FNDC5,PFKFB3,JAM2,HEPACAM,NEGR1,PLXNB3,MEAF6,IFFO1,CP,CHD1L,CRMP1,PPP2R5C,NCAN,RIMS4,FMN2,SLC45A1,IGSF1,CTNND1,PUM1,MASP1,KLK6,RIMS3,SYTL2,ANKS1B,TOMM20,ZNF385B,DNAJC6,ITGAV,CA10,PRDM2,KCNA1,PTPRE,PLPPR4,KCNJ11,KCNK2,OLIG1,RAB5B,DTNA,ZYG11B,NUP214,PHC2,LMO1,FGFBP3,SLC4A10,BAALC" MicroRNA hsa-miR-504:mirSVR_lowEffct hsa-miR-504:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-34 6.20E-31 1.49E-33 1.37E-32 90 1441 "ZFYVE27,EMID1,MBP,ATAT1,LDLRAD3,SLC25A25,ADD3,HOGA1,LRRC7,SEMA6A,HPCAL4,MOBP,SOX6,ANK3,ITSN1,ANXA7,PKP4,SH3GL2,NTNG1,BCAN,BCAS1,SFMBT2,ARFGAP2,SLC14A1,GPR153,TMEM108,IGSF9B,SON,WDTC1,ADAM15,NPAS3,SPART,C11orf87,NCDN,RND1,NHLH1,SEMA4A,ACSL6,CACNB2,TMEM151B,GRIK4,VWCE,SHISA7,USP2,FBXL16,GUCY1A2,TMEM257,ZFP91,DAAM2,PTGDR2,IGFN1,PRMT8,PIRT,FNDC5,GDAP1L1,NMT2,A2ML1,CCSER2,MEAF6,IFFO1,NSD2,PTPA,SNCAIP,ATRNL1,EDRF1,PSMD13,PTAFR,ITIH2,HP1BP3,COPS7A,RGMA,CSDE1,ZC3H11A,PTPRE,KCNK1,DNAH9,DNM2,PLEKHB2,FAM57B,RALGDS,GNE,ABCC9,FAM135B,PHC2,ZNF248,RLBP1,SIDT2,EPB41,EPB41L1,SEZ6" MicroRNA hsa-miR-363:mirSVR_lowEffct hsa-miR-363:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-34 6.40E-31 1.53E-33 1.40E-32 97 1676 "EPS8,C1orf194,ACER3,SYNDIG1,ADARB2,ADD3,GPR158,TESK2,LINC00461,FGF1,BCAR3,UNC79,FOXG1,AMPH,ANK2,RASA3,ITSN1,ANXA7,PKP4,NTNG1,SYBU,AQP4,ZNF365,SORCS3,ASTN1,MEGF11,GABBR1,MYT1L,AHCYL1,ENKUR,NAP1L2,ERBIN,NEUROD1,NFIA,GLS,ZNF638,NKX2-2,DDHD2,UNC5D,BTRC,KLHL4,TBX15,GPM6B,ZEB1,EML4,VXN,VSTM2A,GRIA4,GRIK2,TMEM257,REPS2,CDC42,PCDH8,PCDH9,LGI1,TPD52,PRMT8,PIRT,PDYN,CHGA,CASC2,JAM2,KIAA1549L,BTF3L4,SPATA6,CHD1L,CRLS1,PPP2R5C,PHACTR3,PRKACB,DZIP3,PRKCG,PKN2,NOS1AP,ZNF385B,SIRPA,DNAJC6,PMEPA1,PTHLH,PRDM2,HP1BP3,KCNA1,OCIAD1,SRGAP3,NTM,KCNMA1,SNX27,DLG2,SLC25A48,C12orf4,ABI1,JMJD1C,INSYN2,RLBP1,RERGL,ABI2,FGFBP3" MicroRNA hsa-miR-1911*:mirSVR_lowEffct hsa-miR-1911*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-34 6.53E-31 1.56E-33 1.43E-32 93 1541 "TMEM74,LGR4,EYA1,LDLRAD3,WAC,TUBB4A,FOXRED2,SNX32,LRRTM4,SEMA6A,MOBP,MOG,FOXM1,CDC42BPA,SH3GL2,SORBS1,ST3GAL3,SHTN1,MSR1,LRRC55,SCMH1,ASCL1,PDE8B,LGI3,ATM,USP33,JPH4,TTLL9,ADAM15,ALDH1L1,GPR162,RGL1,ADHFE1,DCLK2,DDHD2,GNG4,MYRF,UNC5D,ADGRL3,TBX15,DDR1,GPR17,PCDHGA3,VXN,GRIA4,GRID1,TF,LEFTY2,TGFBR3,P2RX7,REPS2,PADI2,CDH10,MAGI1,PDE3B,CASC2,HEPACAM,NMT2,OPALIN,TJP2,SULT4A1,C11orf49,BTF3L4,IFFO1,MFSD4A,CHD1L,CRLS1,PPP3CB,FEZ1,MICAL2,PRKACB,CMTM5,IGSF1,PUM1,ECE2,TOX,GON4L,SPIRE1,LRRTM3,PRDM2,PTPRE,KCNJ10,KCNMA1,PID1,RAD52,FAM66C,DPP6,DBX2,BSDC1,FAM135B,SLC4A10,EPB41L1,BAALC" MicroRNA hsa-miR-625*:mirSVR_lowEffct hsa-miR-625*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-34 6.82E-31 1.62E-33 1.49E-32 88 1378 "ACLY,MRVI1,ARID1A,CSMD3,F3,SLITRK1,ADD3,ERMN,NLGN4X,SLC30A10,FOXG1,PPFIA1,SLITRK3,TACC2,SYBU,NLGN1,LRRC4C,SHTN1,ARHGAP5,SLC8A3,SHANK2,USP33,B3GALT2,SOX5,EMC1,NAP1L2,SPART,NDUFA5,ERBIN,LUZP2,DCLK2,MYRF,UNC5D,ADGRL3,KLHL4,ANO4,GPM6A,ACSL6,PRLHR,PTBP2,CECR2,VXN,VSTM2A,GPR88,GRM3,TMEM25,INA,ZFP91,PAH,REPS2,DCLK1,PDE4B,LINC01102,HMGB1,TUB,PRRX1,SPATA6,NSD2,MFSD4A,MED1,CRLS1,SNCAIP,KCNT2,ATRNL1,VCAN,RBPJ,RAB39A,PUM1,PTHLH,OCIAD1,KCNC1,KCNJ10,CCDC3,KCNK1,PCDH15,CAB39L,FAM13C,DTNA,RTN4,PAK5,BSDC1,ABCC9,JMJD1C,TTLL7,SLC39A12,RBM12,RPRD1A,SLC4A10" MicroRNA hsa-miR-4322:mirSVR_lowEffct hsa-miR-4322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-34 6.97E-31 1.66E-33 1.52E-32 91 1476 "ZFYVE27,MBP,EYA1,FAM43B,MRVI1,WLS,ADCY2,DSCAML1,SLITRK1,ERMN,ADORA1,ADORA3,GPR158,FGF1,ASIC4,SELL,ANK3,RASA3,CNIH2,APBB1,KIAA1614,URGCP,MADD,BCO1,PKNOX2,SLC6A9,LGI3,SMARCE1,KBTBD12,ATM,ATP1A2,B4GALNT1,ADGRB2,FXYD6,NCAM1,ALDH1L1,SMOC1,KIRREL3,SEPT3,ZNF638,GNAS,TBX15,PRUNE2,NUCB1,GRID1,CYB561A3,OPCML,TMEM9,TNFRSF1B,TPM4,MAGI1,PRMT8,SCRG1,TLX1,KIAA1549L,PIK3CD,UBTF,NMT2,CCSER2,OPALIN,VAV2,CELF5,PRRX1,SPATA6,NSD2,FAT3,PNKD,RGS6,KCNT2,ATRNL1,SDC3,PLPP4,USP54,NRSN1,ECE2,MASP1,DPYSL5,COPS7A,SMG7,KCNMA1,WIPF2,RALGDS,RASGRF1,GNE,ZNF248,SEC61A2,SFXN5,CACNG7,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-142-3p:mirSVR_lowEffct hsa-miR-142-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-34 7.12E-31 1.69E-33 1.55E-32 80 1130 "ZFYVE27,SYT9,ATAT1,MDM4,SORCS1,AMER2,MOG,AMPH,SGIP1,ANK2,PPFIA1,SESN3,MAGI3,TACC2,MIER1,MSR1,ASPH,BRINP2,SMARCE1,KBTBD12,ILDR2,NAP1L2,NPAS3,RAP1GAP2,NCAM1,LMO3,LUZP2,PRUNE2,VWC2,DDR1,ZEB1,VSTM2A,GRIA1,GRIA2,GPR88,GRM3,INA,TJP1,ZFP91,MAEL,RBFOX2,LGI1,TPD52,TPM3,TPM4,MAGI1,LINC01102,ZMYND8,SCRG1,ANLN,NMT2,SLC36A4,FAT3,ACBD5,POU3F4,OSBPL3,NCAN,DOCK7,DZIP3,PLD5,CTNND1,TOX,KIAA0513,ANKS1B,BDNF-AS,PRDM2,OLFM3,KCNA4,AK5,KCNJ10,PCDH15,KLRC2,FAM13C,DTNA,USH1C,JMJD1C,SEC61A2,SH3GLB1,RPRD1A,ARHGAP12" MicroRNA hsa-miR-4323:mirSVR_lowEffct hsa-miR-4323:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-34 7.66E-31 1.81E-33 1.66E-32 90 1445 "EPS8,SERPINA3,ZFYVE27,MAP6,ACHE,SYNDIG1,MEG3,FAM43B,LDLRAD3,RTKN,MDM4,NDRG2,NLGN4X,TESK2,FGF1,ASIC4,SLC30A10,MOBP,ASRGL1,ANK3,RASA3,ITSN1,PPM1E,SORBS1,ST3GAL3,PAAF1,AQP4,ZNF365,BCO1,ARHGAP5,SORCS3,GABBR1,SON,ARPP21,KIF1B,NASP,NFASC,NCAM1,BCL2L2,SMOC1,GPR162,INKA2,RGL1,PHLDB1,SEPT3,PCDH11X,ZNF638,ROBO3,ADGRL3,ATF7,PCDHGA3,OPCML,LINC00839,TMEM25,P2RX7,ZFP91,MAEL,PADI2,TNS1,PTGDR2,PRMT8,FNDC5,ASIC3,GDAP1L1,CAMKV,PIK3CD,A2ML1,OPALIN,CELF5,IFFO1,MFSD4A,RGS6,MICAL2,PRKCZ,ECE2,PSD,KIAA0513,PSMD13,COPS7A,KCNC1,KCNK1,KCNK2,TMEM255A,PLEKHB2,PARP11,DPP6,GNE,ARHGEF10L,YY1AP1,EPB41" MicroRNA hsa-miR-590-5p:mirSVR_highEffct hsa-miR-590-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.43E-34 7.76E-31 1.83E-33 1.68E-32 85 1285 "SDE2,ABAT,PRR5L,TMEM74,ADCY2,TESK2,SCN3A,KIAA1109,FGF1,SLC30A10,MOBP,SGIP1,SORBS1,ZNF365,ARHGAP5,ARFGAP2,SLC8A3,SMARCE1,RCOR3,SNCB,MEGF11,USP33,SOX5,ARPP21,SALL3,NEK6,NPAS3,STOX1,ARHGEF7,LUZP2,CAMTA1,PSRC1,GPM6B,FAM69C,ZEB1,PTBP2,GRIA2,GRIA4,RFFL,OLR1,INA,TIE1,HPS5,RBFOX2,PDE4B,BEST3,HPSE2,ANO5,CASC2,HNRNPK,CADM1,NEGR1,CCSER2,CNTN1,CELF5,BTF3L4,SNCAIP,KCNT2,OSBPL3,ATRNL1,RBPJ,PRKACB,MAPK10,EDRF1,ANKS1B,PRTFDC1,COPS7A,MED24,OLFM3,C1orf109,KCNN3,CAB39L,HS3ST4,PID1,DNM2,RTN4,ABCC9,NUP214,SSPN,RPRD1A,RAVER2,PLEKHO1,RPE65,EPB41L1,RCAN2" MicroRNA hsa-miR-619:mirSVR_lowEffct hsa-miR-619:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-34 8.93E-31 2.10E-33 1.93E-32 97 1683 "ZFYVE27,TMEM74,ARID1A,PNMA8B,SNX30,TOMM40L,SCN4B,DISP3,SEMA6A,FGR,SOX6,PPFIA1,ITSN1,BCAN,ZNF365,SFMBT2,SLC8A3,MT3,SHANK2,SLC14A1,SMARCE1,RCOR3,TMEM108,ATP2B2,DKK3,SON,CAB39,GAD2,AHCYL1,NMNAT2,ARPP21,COLGALT2,ALDH1L1,RGL1,PHLDB1,ARHGEF7,GLS,GNAS,CDK5R2,TMEM136,ANO4,CACNA1E,CACNB2,VXN,BRSK2,GRIA1,GRIK2,CYB561A3,OPCML,TGFBR3,TMEM9,REPS2,PC,PADI2,DCLK1,LGI1,PCSK2,ZNF384,PDE1A,LRTM2,PFKFB3,ASIC3,CELF5,CHD1L,SF1,PPP2R5C,OSBPL3,VCAN,NCAN,ARHGEF4,WBP1L,LRRTM3,PTCH1,CA10,BDNF-AS,COPS7A,MAGI2,KCNA1,CDH20,SMG7,PTPRE,C1orf109,SV2A,KCNJ9,KCNK1,WIPF2,PLEKHB2,GNE,ABCC9,RET,RFX5,PHC2,VWA5A,FGFBP3,SLC4A10,YY1AP1,EPB41" MicroRNA hsa-miR-1290:mirSVR_highEffct hsa-miR-1290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.66E-34 9.01E-31 2.12E-33 1.94E-32 94 1581 "SERPINA3,RPL38,ACER3,LGR4,CSMD2,MDM4,F3,RTN1,GALNT13,FABP7,PNMA8B,NLGN4X,TOMM40L,SCN3A,LRRC7,UNC79,AMPH,JAKMIP3,BCAS1,MSR1,ARHGAP5,CCDC88A,ASPH,BRINP2,SMARCE1,NRG3,PHYHIPL,DKK3,ENKUR,ARPP21,TTLL9,NPAS3,NDUFA5,RCOR2,ARHGEF7,PCDH11X,ZNF638,NKX2-2,DDHD2,UNC5D,MMD2,ANO4,VWC2,CAMK2A,GRIA2,GRIA4,ADAMTS8,LGI1,TPM4,MAGI1,PDE3B,PRMT8,PDYN,BEST3,JAM2,NLGN3,CADM1,NRXN1,A2ML1,DNAJC12,PMP2,BEST1,SLC36A4,PACSIN1,FAT3,CP,POU3F2,CHD5,VCAN,RBPJ,FMN2,PLPP4,CTNND1,PUM1,FAM131B,WBP1L,LRRTM3,DNAJC6,ITGAV,CADM2,PRDM2,PRTFDC1,STMN4,BLOC1S6,OCIAD1,SMG7,KCNK2,PCDH15,DLG2,TMEM255A,RALGDS,RFX4,EN2,UEVLD" MicroRNA hsa-miR-548m:mirSVR_highEffct hsa-miR-548m:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-34 9.24E-31 2.16E-33 1.99E-32 100 1788 "ACER3,MDM4,CSMD3,CLIP1,KLHL32,DSCAML1,SLITRK1,CDC7,ERMN,AMER2,SCN3A,HPCAL4,MOG,PPFIA1,SH3GL2,MAGI3,API5,SHTN1,MSR1,CCDC88A,SCMH1,SORCS3,SMARCE1,RCOR3,TMEM108,ATP1A2,PALLD,USP33,SON,TNIK,ILDR2,FXYD6,NPAS3,NFASC,C11orf87,RGL1,NEUROD1,PCDH11X,ZNF638,CAMSAP2,ADGRL3,ANO4,TBX15,PRUNE2,GPM6A,GPM6B,LRIT2,ZEB1,CAMK2G,VSTM2A,NUCB1,GRM3,OLR1,CRB1,INA,TJP1,ZFP91,CD81,PCDH9,LGI1,TPM3,MAGI1,HMGB1,CADM1,ANLN,SPATA6,P2RY12,CNRIP1,MFSD4A,KCNT2,RBPJ,PLD5,KIAA0408,ANKS1B,GON4L,TUBB2B,ZNF385B,DNAJC6,ITGAV,CEP170,CDH20,PTPRD,SMG7,C1orf109,PTPRZ1,PCDH15,KIF2A,PLEKHB2,FAM66C,DSCAM,GNE,PAK5,ABCC9,RFX4,ZNF248,RBM12,RPRD1A,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-135b:mirSVR_lowEffct hsa-miR-135b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-34 1.03E-30 2.40E-33 2.20E-32 102 1861 "DPF1,ACER3,APC2,ADARB2,KLHL32,ADCY2,WAC,SLC44A5,GPR158,LINC00461,PLA2G6,SEMA6A,UNC79,ELMOD1,CDC42BPA,ANK1,PPFIA1,ITSN1,NLGN1,CLSTN1,SLC1A6,SHANK2,NSG2,DACH2,CAPRIN2,SLN,SORCS3,RCOR3,ATP2B2,SCN3B,WDTC1,MYT1L,KIF21B,AHCYL1,NMNAT2,B4GALNT1,SALL3,KIF1B,NFASC,ALDH1L1,PCDH11X,ZNF638,DCLK2,DDHD2,CAMTA1,PRUNE2,CACNA1E,ZEB1,NUDT21,VXN,GRIA2,GRIN1,OMG,SHISA7,TLL2,TNS1,CDH8,RBFOX2,ARHGAP19,LGI1,MAGI1,PDE1A,PDE2A,PRMT8,PDYN,FNDC5,ANO5,CASC2,HNRNPK,JAM2,NEGR1,CCSER2,TJP2,ST8SIA5,PLXNB3,NSD2,PNKD,RNF14,SNCAIP,RBPJ,ARHGEF4,TOX,SPIRE1,SYNC,BDNF-AS,PRDM2,PTPRE,NTM,RABGAP1L,DLG2,DNM2,SLC25A18,DTNA,BSDC1,ZYG11B,NUP214,ATL1,TTLL7,SEC61A2,LPAR6,CBLN2,EPB41" MicroRNA hsa-miR-654-5p:mirSVR_lowEffct hsa-miR-654-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-34 1.05E-30 2.45E-33 2.25E-32 95 1618 "RABEPK,WLS,ADARB2,CHST15,MOBP,TRIM46,ANK1,ITSN1,DOCK10,MAGI3,DGKZ,DGKD,SORBS1,ZNF365,RPH3A,MADD,SLC8A3,MT3,SPHKAP,B3GAT1,SNAP25,SNCB,ATP1A2,KIF21B,CADM3,SOX10,ZSWIM8,B4GALNT1,IDI2-AS1,FXYD6,NFASC,LMO3,KIRREL3,PCDH11X,C1QC,OS9,GNAS,GNG3,MYRF,CACNA1A,PRUNE2,GPM6B,DDR1,CACNB2,NRGN,HAP1,AZIN2,TMEM151B,GRIA1,GRIA4,GRID1,RFFL,GRIN1,GPR88,CYB561A3,USP2,HPS5,PADI2,HRH3,PDE4B,HAPLN2,BEST3,CHGA,ASIC3,CASC2,DLGAP3,PLXNB3,C11orf49,MEAF6,PRRX1,NECAB2,FAT3,CP,SNCAIP,NKAIN4,RBPJ,MASP1,WBP1L,PHYHIP,KCNA6,NTM,TMCC2,KCNJ11,KCNK1,KCNMA1,DNM2,RAP1GAP,ABI1,RASGRF1,DBX2,CAMK1G,USH1C,RFX4,LMO1,EN2" MicroRNA hsa-miR-3138:mirSVR_lowEffct hsa-miR-3138:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-34 1.09E-30 2.53E-33 2.32E-32 103 1898 "RABEPK,ASIC1,SYT9,MEG3,MRVI1,LDLRAD3,F3,GALNT13,ADD3,SNX30,NLGN4X,CHST15,LRRTM4,SCNN1D,SLC30A10,ANK3,RASA3,PPFIA1,ITSN1,MAGI3,DGKZ,DGKD,PAAF1,MIER1,MADD,PKNOX2,SLC8A3,CCDC88A,ASPH,ASTN1,RCOR3,TMEM108,USP33,SOX1,NMNAT2,SALL3,KIF1B,SPART,NFASC,ALDH1L1,DCAF5,FGF17,SEPT3,VAMP1,CASTOR3,CAMSAP2,UNC5D,MMD2,CNDP1,KLHL4,ACSL6,TCF7L2,BRSK2,GRID1,OMG,SHISA7,TGFBR3,GUCY1A1,TLL2,ZFP91,PC,CDH10,LGI1,PCSK2,PRMT8,ASIC3,PLEKHB1,FADS2,IFFO1,SNCAIP,MICAL2,OSBPL3,ATRNL1,PRKACB,RAB39A,PRKCZ,CTNND2,NRSN1,NOS1AP,PHYHIP,GON4L,SPIRE1,SIRPA,MAGI2,OCIAD1,PTPRD,SMG7,PTPRE,KCNH1,PEX5,DLG2,NKAIN1,PID1,DPP6,RAP1GAP,BSDC1,RFX5,JMJD1C,SYT15,ELAVL4,EPB41L1,SEZ6,UEVLD" MicroRNA hsa-miR-4327:mirSVR_lowEffct hsa-miR-4327:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.04E-34 1.11E-30 2.57E-33 2.35E-32 82 1198 "SERPINA3,ABAT,RCSD1,MDM4,ADARB2,WAC,NLGN4X,CHST15,GPR158,HOGA1,ASIC4,FHL1,ELMOD1,SGIP1,NTNG1,ST3GAL3,JAKMIP3,MIER1,KIAA1614,SLC14A1,ASPH,SMARCE1,ALDH4A1,SALL3,STOX1,FAM168A,VAMP1,PCDH11X,POPDC3,DCLK2,PSRC1,ANO4,CLEC9A,TCF12,HAP1,AZIN2,NUDT21,NUMA1,GRIA2,GRIK2,TNFRSF1B,TNR,PADI2,PCDH9,ARHGAP19,LGI1,PRMT8,PIRT,FNDC5,HMGB1,PFKFB3,TUB,HEPACAM,BEST1,P2RY12,ACBD5,SF1,KCNT2,VCAN,RBPJ,PRKAB2,CTNND1,ECE2,NOS1AP,ELMO1,RGMA,CEP170,ZC3H11A,KCNA4,PTPRE,PTPRZ1,KCNH1,PARP11,JMJD1C,FAM135B,ZNF248,PIANP,ABI2,RAVER2,OLIG2,RPE65,EPB41L1" MicroRNA hsa-miR-512-5p:mirSVR_lowEffct hsa-miR-512-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.05E-34 1.11E-30 2.57E-33 2.36E-32 99 1757 "SERPINA3,SDE2,ZFYVE27,SYNDIG1,CEND1,ACTN2,MDM4,CSMD3,ADAR,SORCS1,FCGR1A,TOMM40L,SEMA6A,HPCAL4,ITSN1,PPM1E,DGKZ,ZCCHC17,ZNF365,BCO1,MT3,DACH2,GPR153,DDX25,RCOR3,ADGRA1,ALDH4A1,SNAP25,ATM,GABBR1,SOX1,B3GALT2,ZSWIM8,ARPP21,SPART,LMO3,ZNF302,ARHGEF7,PCDH11X,SYT4,CAMTA1,GNG4,UNC5D,PRUNE2,PRLHR,VXN,VSTM2A,NUMA1,GRIK2,GRIK3,CRB1,PTPN5,CD81,TNS1,PCDH9,RBFOX2,MAGI1,PDE3B,GPR37L1,MS4A7,SEMA5B,NOMO2,NMT2,A2ML1,TJP2,CCDC136,NXPH1,SNCAIP,PKN2,USP54,CTNND1,ANKS1B,SPIRE1,TUBB2B,PRDM2,HP1BP3,BLOC1S6,ZC3H11A,OCIAD1,SMG7,PTPRO,SRGAP3,RABGAP1L,KCNJ10,TMCC2,KCNK2,KCNN3,WIPF2,PARP11,RALGDS,RET,RFX5,SYT15,RNF220,ABI2,SLC4A10,YY1AP1,OLIG2,PRRT4" MicroRNA hsa-miR-138-2*:mirSVR_highEffct hsa-miR-138-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.11E-34 1.14E-30 2.64E-33 2.42E-32 89 1420 "ABAT,LOC100128239,ACER3,SYT9,EYA1,CSMD2,ADD3,CDC7,FCGR1A,GPR158,SCN3A,LRRC7,FOXG1,SOX6,FOXM1,SFPQ,APBA2,DGKZ,MIER1,ARFGAP2,YPEL4,CCDC88A,SCG3,CSPG5,TAGLN3,SNAP25,FYN,PHYHIPL,DKK3,USP33,TNIK,ILDR2,AHCYL1,ARPP21,LMO3,CLASP2,RGL1,ABCC8,GLS,POPDC3,CAMTA1,ADGRL3,GPM6B,TCF12,GRIA2,GRIA4,RFFL,OPCML,AIFM1,TMEM257,CDH8,LGI1,TPD52,PDE3B,TMEFF2,GDAP1L1,PIK3CD,A2ML1,TJP2,MEAF6,NSD2,POU3F2,CHD1L,KCNT2,FEZ1,VCAN,DZIP3,PKN2,PLD5,CTNND2,PROX1,ZBTB16,TOX,ZNF385B,DNAJC6,PLPPR4,SV2A,KCNK1,KCNK2,KLRC2,SLC17A6,GOPC,DTNA,RFX4,ZNF248,RPRD1A,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-593:mirSVR_lowEffct hsa-miR-593:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-34 1.19E-30 2.75E-33 2.52E-32 104 1936 "ASIC1,MBP,MEG3,CSMD2,KCNIP2,CSMD3,RTN1,FABP7,ERMN,KIAA1109,BCAR3,GOLGA7B,ELMOD1,ANK3,PPFIA1,ITSN1,PKP4,PPM1E,CACHD1,ST3GAL3,LRRC55,SLC8A2,NSG2,DACH2,CAPRIN2,ASPH,BRINP2,B3GAT1,TMEM108,ATM,NRG3,EIF4G3,PHYHIPL,MEGF11,DKK3,TNIK,SOX5,ENKUR,ADGRB2,SPART,PHLDB1,VAMP1,ZNF638,NKX2-2,GNAS,GNG4,BTRC,WWC1,GPM6A,GPR19,BRSK2,GRIA4,GRID1,SHISA7,OPCML,CELF3,NEURL1,CDH8,RBFOX2,HRH3,TPM3,PDE4B,PFKFB3,CASC2,TUB,GDAP1L1,NEGR1,UBTF,FTO,CNTN1,PACSIN1,POU3F2,SNCAIP,FEZ2,OSBPL3,PRKCG,KIAA0408,PSD,KIAA0513,DPYSL5,ANKS1B,SYNC,SIRPA,DNAJC6,BDNF-AS,RGMA,MAGI2,PTPRE,C1orf109,KCNH1,KCNMA1,PEX5,DLG3,PLEKHB2,DPP6,RASGRF1,BSDC1,FAM135B,SH3GLB1,VWA5A,RAVER2,SLC4A10,EPB41L2,BAALC" MicroRNA hsa-miR-548d-3p:PITA hsa-miR-548d-3p:PITA_TOP PITA 2.32E-34 1.26E-30 2.89E-33 2.65E-32 65 721 "RIMKLA,ARID1A,RTN1,SORCS1,SNX30,GPR158,SCN3A,UNC79,ELMOD1,PDZD4,AMPH,CDC42BPA,DOCK10,APC,NLGN1,ST8SIA1,CCDC88A,MYT1L,ZCCHC24,CAB39,COLGALT2,ERBIN,FAM168A,CAMTA1,CAMSAP2,UNC5D,BTRC,CNTN2,SYT6,NUMA1,BRSK2,PSD3,GRIA2,GRIA4,GRIK2,GPR88,PCDH9,RBFOX2,NLGN3,DLGAP3,NRXN1,NEGR1,VAV2,MEAF6,PRRX1,MED1,RBPJ,TOX,LRRTM3,CADM2,RGMA,CSDE1,KCNA1,PTPRD,SMG7,PTPRZ1,NKAIN1,PID1,PARP11,ABI1,BSDC1,RBM12,ELAVL3,EPB41,RCAN2" MicroRNA hsa-miR-515-5p:mirSVR_highEffct hsa-miR-515-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-34 1.27E-30 2.91E-33 2.67E-32 96 1656 "ADGRV1,RTKN,ADD3,CDC7,SORCS1,GPR158,SCN4B,KIAA1109,SGIP1,PPFIA1,ITSN1,SLITRK3,ST3GAL3,API5,SHTN1,ZNF365,RUFY2,SLC8A3,ASCL1,ASPH,SMARCE1,RCOR3,ATM,ATP1A2,NRG3,MEGF11,B3GALT2,CAB39,ARPP21,ADAM15,KIF1B,SPART,C11orf87,NDUFA5,AJAP1,ARHGEF7,ZNF638,LUZP2,DDHD2,CAMSAP2,CACNA1A,TCF12,PTBP2,GRIA1,GRIA2,GRIA4,MAEL,CDC42,PTGDR2,LGI1,TPM3,PDE1A,PDE3B,LINC01102,ZMYND8,SEMA5B,CHD1L,MED1,CRLS1,PPP2R5C,SNCAIP,FEZ2,DZIP3,PKN2,PLD5,USP54,PUM1,NOS1AP,BRINP3,ZNF385B,PSMD13,DNAJC6,CADM2,PRDM2,HP1BP3,COPS7A,CEP170,KCNA4,OCIAD1,PTPRD,RABGAP1L,CCDC3,KCNK2,KIF2A,SUSD4,PAK5,ABCC9,SLC6A15,RFX4,ZNF248,SEC61A2,SSPN,EFNA3,RERGL,RAVER2,RASGRP2" MicroRNA hsa-miR-143*:mirSVR_lowEffct hsa-miR-143*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.35E-34 1.27E-30 2.91E-33 2.67E-32 94 1588 "ZFYVE27,ACER3,CNTNAP3,WLS,RTN1,GALNT13,DRAXIN,ELMOD1,HPCAL4,SOX6,TRIM46,SGIP1,ANK2,ANK3,USP28,CNIH2,PPM1E,SLITRK3,NLGN1,ST3GAL3,MT3,GPR153,ASTN1,ALDH4A1,MEGF11,NMNAT2,SALL3,ADAM15,KIF1B,ADGRB2,DNER,NAP1L2,NFASC,ALDH1L1,RGL1,NEUROD1,ARHGEF7,PCDH11X,ZNF638,DDHD2,GNG4,BTRC,ADGRL3,CNDP1,CACNB2,ZEB1,VSTM2A,GRIA2,OLR1,OMG,TMEM25,CDK11B,CDC42,PCDH9,ARHGAP19,IGFN1,PIRT,TUB,PIK3CD,TJP2,FLRT1,PLXNB3,SLC25A27,BEST1,FAT3,CNRIP1,PPP3CB,ATRNL1,PRKACB,DZIP3,PRKCG,PRKCZ,CTNND1,NRSN1,TOX,PLPPR1,CEP170,CSDE1,PTPRD,PTPRZ1,NTM,NAV2,DNM2,RALGDS,ABI1,DTNA,SLC6A15,CRTAC1,JMJD1C,INSYN2,ZNF248,TMEM100,EPB41L1,SEZ6" MicroRNA hsa-miR-519b-5p:mirSVR_lowEffct hsa-miR-519b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-519c-5p:mirSVR_lowEffct hsa-miR-519c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-519a*:mirSVR_lowEffct hsa-miR-519a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-522*:mirSVR_lowEffct hsa-miR-522*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-518e*:mirSVR_lowEffct hsa-miR-518e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-523*:mirSVR_lowEffct hsa-miR-523*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-34 1.32E-30 2.97E-33 2.73E-32 93 1555 "EPS8,PRR5L,ASIC1,CDHR1,CSMD3,CLIP1,ADCY2,GALNT13,TUBB4A,AMER2,NLGN4X,LRRC7,FHL1,ELMOD1,HPCAL4,ASRGL1,ANXA7,APBA2,SESN3,APC,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,SHANK2,ASCL1,PDE8B,SLIT1,RCOR3,C10orf105,TMEM108,SON,SOX5,CAB39,GAD2,EMC1,TTLL9,BCL2L2,NDUFA5,PCDH11X,KAZN,CAMSAP2,BTRC,ADGRL3,TBX15,PRUNE2,VWC2,GPR17,TCF12,PTBP2,NUDT21,EML4,SYT6,GRIA2,RFFL,CRB1,TJP1,CELF3,CDH8,DCLK1,ARHGAP19,JAM2,CADM1,A2ML1,FAT3,ATCAY,RNF14,PPP2R5C,PRKAB2,FAM131B,PROX1,ANKS1B,PHYHIP,PLPPR5,ITGAV,CA10,PTHLH,BLOC1S6,ZC3H11A,PLPPR4,KCNC1,NTM,ARNT2,PCDH15,DPP6,RASGRF1,PAK5,ABCC9,SSPN,SH3GLB1,ABI2,ARHGAP12" MicroRNA hsa-miR-626:mirSVR_lowEffct hsa-miR-626:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.65E-34 1.43E-30 3.23E-33 2.96E-32 91 1490 "ACLY,SYT9,LDLRAD3,KCNIP2,PLEKHG5,CDC7,SEMA6A,FOLH1,USP28,SH3GL2,PPM1E,ZCCHC17,LRRC4C,CLSTN1,RPH3A,SFMBT2,SLCO1A2,ARFGAP1,SORCS3,SMARCE1,MEGF11,MYT1L,ARPP21,ADAM15,NPAS3,NFASC,ALDH1L1,STOX1,DCAF5,NCDN,ADHFE1,ARHGEF7,ZNF638,DDHD2,PSRC1,CACNA1A,GPM6B,ATF7,ZEB1,EML4,VXN,VSTM2A,CCKBR,TMEM25,LEFTY2,TIE1,ZDHHC22,MS4A7,HNRNPK,DUSP26,CADM1,CCSER2,OPALIN,FAT3,FAAP20,NXPH1,CHD1L,SF1,TENM4,RGS6,OSBPL3,RBPJ,FMN2,KIAA1755,NRSN1,BRINP3,TOX,WBP1L,DPYSL5,SPIRE1,SIRPA,BDNF-AS,CNIH3,HP1BP3,LRP8,SMG7,PTPRO,SRGAP3,NTM,KCNMA1,OLIG1,DNAH9,DPP6,RALGDS,C12orf4,RAP1GAP,SLC6A15,ZYG11B,RFX5,RLBP1,BAALC" MicroRNA hsa-miR-3149:mirSVR_highEffct hsa-miR-3149:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-34 1.48E-30 3.33E-33 3.06E-32 80 1142 "RABEPK,MEG3,CSMD3,ADORA3,LRRTM4,LINC00461,KIAA1109,LRRC7,ITSN1,ANXA7,NLGN1,PAAF1,AQP4,ZNF365,MSR1,CCDC88A,SPHKAP,ASPH,SMARCE1,RCOR3,NRG3,MYT1L,B3GALT2,ARPP21,KIF1B,NPAS3,C11orf87,NELL1,NEUROD1,ARHGEF7,VAMP1,PCDH11X,NHLH1,LUZP2,CAMTA1,ANO4,ATF7,TCF7L2,ZEB1,PTBP2,GRIA4,OLR1,OPCML,GUCY1A2,TJP1,MAEL,PAX6,MAGI1,PDE3B,PDE4B,CASC2,CADM1,NRXN1,ANLN,NSD2,CNRIP1,MFSD4A,CP,POU3F2,NKAIN4,ATRNL1,NCAN,PLD5,PRKCZ,ANKS1B,TOMM20,PTAFR,DNAJC6,CA10,PTHLH,PRDM2,HP1BP3,OLFM3,KCNA4,PTPRE,KIF2A,C12orf4,ABCC9,RFX4,VWA5A" MicroRNA hsa-miR-509-3p:mirSVR_lowEffct hsa-miR-509-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.91E-34 1.58E-30 3.53E-33 3.24E-32 80 1143 "SERPINA3,ATAT1,ARID1A,MDM4,GALNT13,WAC,SLC44A5,MOBP,ANK3,DOCK10,MAGI3,GAS7,SORBS1,ZNF365,PKNOX2,MT3,ASCL1,SCG3,CAPRIN2,ATP1A3,NCAM1,PCDH11X,DDHD2,GNG4,ADGRL3,ZEB1,GRIA1,GRIA2,GRIA4,RFFL,GPR88,OLR1,CRB1,GUCY1A2,NEURL1,DAAM2,PADI2,PCDH8,DCLK1,LGI1,TPM3,MAGI1,LINC01102,ANO5,ASIC3,NLGN3,NEGR1,NMT2,A2ML1,CABP1,PRRX1,CP,RBPJ,DZIP3,FMN2,KIAA1755,CTNND1,FGFR1OP2,ANKS1B,ITGAV,BDNF-AS,CADM2,PRDM2,PTPRD,KCNC1,KCNJ10,NKAIN1,DNM2,PARP11,ATN1,GOPC,DTNA,PAK5,ST8SIA3,RFX5,SSPN,ABI2,ELAVL4,EN2,OLIG2" MicroRNA hsa-miR-3171:mirSVR_lowEffct hsa-miR-3171:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.96E-34 1.60E-30 3.58E-33 3.29E-32 102 1871 "EPS8,ACLY,LGR4,EYA1,CSMD2,MDM4,KLRC4,ADD3,FABP7,SLC44A5,LRRC7,ANXA7,PPM1E,NLGN1,BCAS1,USP16,SLC7A14,RUFY2,SORCS3,RCOR3,EIF4G3,WDTC1,B3GALT2,AHCYL1,NAP1L2,STOX1,NEUROD1,AJAP1,NFIA,GLS,NHLH1,C1QC,SYT4,LUZP2,BTRC,ADGRL3,ANO4,ATF7,VWC2,LILRA1,TCF7L2,ZEB1,TCF12,PTBP2,VXN,GRIA1,ATP13A2,LINC00839,CRB1,MFSD2A,TJP1,PAH,PADI2,PCDH9,PCSK2,CASC2,MS4A7,TMEFF2,SERPINE2,KIAA1549L,ANLN,PMP2,P2RY12,SLC36A4,ATRNL1,PLCH2,NCAN,PRKACB,PLD5,USP54,EDRF1,FAM131B,BRINP3,LRRTM3,CA10,JAKMIP2,CADM2,ELMO1,CEP170,MAGI2,OCIAD1,SRGAP3,NTM,DLG2,HS3ST4,DNAH9,FAM66C,FAM13C,DBX2,ZYG11B,RFX5,JMJD1C,FAM135B,ATL1,VANGL2,SEC61A2,EFNA3,RPRD1A,ELAVL4,EN2,TMEM100,EPB41L2" MicroRNA hsa-miR-26b:mirSVR_highEffct hsa-miR-26b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.01E-34 1.63E-30 3.64E-33 3.34E-32 95 1627 "SDE2,PRR5L,CNTNAP3,LGR4,ACTN2,MEG3,RTN1,SORCS1,ERMN,KIAA1109,FGF14,SEMA6A,SLC30A10,MOG,SEMA6C,SFPQ,SGIP1,ANK1,APC,NLGN1,SHTN1,MIER1,SLC1A6,RUFY2,CCDC88A,DACH2,SLCO1A2,SORCS3,SMARCE1,ATP1A2,PALLD,USP33,MYT1L,ZCCHC24,CAB39,ARPP21,NEK6,NPAS3,CLASP2,STOX1,ERBIN,GLS,VAMP1,ZNF638,SYT4,POPDC3,ADGRL3,KLHL4,CACNB2,TCF7L2,VXN,NUMA1,GRIA4,RFFL,PCDH8,PCDH9,LGI1,PDE3B,LINC01102,BEST3,PFKFB3,NRXN1,TJP2,PMP2,CELF5,SPATA6,ACBD5,CRLS1,PPP2R5C,SNCAIP,PPP3CB,KCNT2,RBPJ,DZIP3,CTNND2,ANKS1B,TUBB2B,LRRTM3,JAKMIP2,PRTFDC1,PTPRD,PLPPR4,KCNK1,DLG2,OLIG1,TMEM255A,RALGDS,FAM13C,DTNA,SLC6A15,ZYG11B,JMJD1C,VANGL2,RBM12,RPRD1A" MicroRNA hsa-miR-1302:mirSVR_lowEffct hsa-miR-1302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.05E-34 1.65E-30 3.67E-33 3.37E-32 92 1526 "LGR4,FAM43B,ARID1A,WLS,SLC25A25,NDRG2,ADARB2,NLGN4X,CHST15,HOGA1,SCN4B,KIAA1109,FGF14,ASIC4,TRIM46,SFPQ,PPFIA1,SORBS1,API5,SHTN1,AQP4,SFMBT2,NAXD,ASPH,BRINP2,SORCS3,NRG3,FYN,CADM3,GAD2,ZSWIM8,FXYD6,NPAS3,ALDH1L1,GFAP,ADHFE1,NHLH1,SEMA4A,DDHD2,TBX15,GPM6A,FAM69C,CACNA1E,CACNB2,LILRA1,TCF12,NUCB1,CYB561A3,OLR1,P2RX7,PAX6,PC,CDC42,PADI2,TNS1,ADGRG1,PLEKHB1,FTO,PRRX1,P2RY12,NSD2,FAT3,MFSD4A,SNCAIP,OSBPL3,PRKCG,USP54,IGSF1,EDRF1,KIAA0408,SPIRE1,SYNC,PTCH1,PRDM2,PRTFDC1,BLOC1S6,PTPRD,SMG7,PTPRE,KCNMA1,KCNN3,DLG2,WIPF2,SLC17A6,FAM66C,ATG16L1,GOPC,NUP214,JMJD1C,PHC2,ZNF248,EPB41L1" MicroRNA hsa-miR-339-5p:mirSVR_lowEffct hsa-miR-339-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.20E-34 1.73E-30 3.85E-33 3.54E-32 92 1527 "RABEPK,ZFYVE27,CSMD2,SLITRK1,GRAMD1B,FOXRED2,SNX32,TESK2,LRRTM4,FHL1,MOBP,PDZD4,CDC42BPA,SESN3,DGKD,CACHD1,ZNF365,MSR1,SLC8A3,NSG2,CGREF1,SLCO1A2,ARFGAP1,SORCS3,ATM,PALLD,SON,ZSWIM8,AHCYL1,ARPP21,LHFPL4,KIF1B,NPAS3,ERBIN,GFAP,NCDN,PHLDB1,VAMP1,LUZP2,BTRC,ADGRL3,PRUNE2,ACSL6,AKNA,CYB561A3,LEFTY2,TGFBR3,USP2,TMEM257,ZDHHC22,ZFP91,C1orf94,SEZ6L,TPM3,TPM4,IGFN1,LINC01102,ADGRG1,PFKFB3,ASIC3,CHRM1,TUB,HNRNPK,NLGN3,NMT2,TJP2,CHD1L,SNCAIP,RGS6,FEZ2,ATRNL1,PRKACB,RAB39A,PRKCZ,EDRF1,TOX,BDNF-AS,PRDM2,ZC3H11A,PTPRO,AK5,KCNMA1,GOPC,GNE,SLC6A15,NUP214,GPR61,FGFBP3,ARHGAP12,ELAVL3,EN2,EPB41L2" MicroRNA hsa-miR-135a*:mirSVR_lowEffct hsa-miR-135a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.67E-34 1.99E-30 4.41E-33 4.05E-32 82 1208 "MAP6,CDHR1,EYA1,MRVI1,MDM4,KLHL32,ADCY2,GALNT13,SORCS1,TOMM40L,HOGA1,PDZD4,SFPQ,ERICH3,BCAN,TACC2,SORBS1,JAKMIP3,BCAS1,DLL3,ASPH,SMARCE1,RCOR3,ATP1A2,KIF21B,NMNAT2,ARPP21,TTLL9,IDI2-AS1,RAP1GAP2,NFASC,ALDH1L1,GFAP,ASTN2,DDHD2,GNG4,ATF7,NRGN,HAP1,TMEM151B,VXN,GRM3,SHISA7,LEFTY2,FBXL16,INA,P2RX7,HPS5,SEZ6L,ASIC3,CASC2,RGS6,KCNT2,OSBPL3,NCAN,FMN2,RAB39A,WBP1L,PTCH1,PRTFDC1,HP1BP3,RGMA,MAGI2,OCIAD1,SRGAP3,KCNK1,KCNK2,KCNMA1,PEX5,DLG2,FAM13C,DTNA,ZYG11B,RFX4,INSYN2,SEC61A2,SLC39A12,ABI2,VWA5A,EPB41,EPB41L2,RCAN2" MicroRNA hsa-miR-3122:mirSVR_lowEffct hsa-miR-3122:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.69E-34 2.00E-30 4.41E-33 4.05E-32 88 1398 "PRR5L,MAPT,MBP,RTN3,ADCY2,CHST15,TESK2,KIAA1109,LRRC7,SEMA6A,TRIM46,ANK3,DGKD,SORBS1,ST3GAL3,SHTN1,YPEL4,ASPH,SORCS3,ASTN1,SMARCE1,PHYHIPL,B3GALT2,CADM3,GAD2,ZSWIM8,ADGRB2,NCAM1,CLASP2,BCL2L2,NDUFA5,ADHFE1,ARHGEF7,VAMP1,NHLH1,KLHL4,PRUNE2,GPM6A,ATF7,CACNA1E,TCF7L2,ZEB1,AZIN2,NUCB1,GRID1,GRIK2,CYB561A3,OLR1,CRB1,ZDHHC22,LGI1,PCSK2,PRMT8,PDYN,ZMYND8,DNAJC12,FTO,BTF3L4,SPATA6,SLC36A4,MED1,SF1,CRMP1,PTPA,SNCAIP,NKAIN4,PRKACB,SDC3,KIAA0408,TOX,ELMO1,OCIAD1,KCNC1,C1orf109,KCNJ9,KCNK2,PCDH15,SLC17A6,ATG16L1,SUSD4,DTNA,BSDC1,ABCC9,NUP214,RFX4,FAM135B,SFXN5,CBLN2" MicroRNA hsa-miR-1324:mirSVR_highEffct hsa-miR-1324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.83E-34 2.08E-30 4.58E-33 4.20E-32 81 1178 "EPS8,SDE2,MAPT,ACLY,DUSP27,ACTN2,LDLRAD3,SLITRK1,ADD3,WAC,NLGN4X,LRRTM4,FHL1,AMPH,CNIH2,ITSN1,APBB1,MIER1,CSPG5,SLCO1A2,ASPH,MTR,SNCB,MEGF11,MYT1L,TNIK,ARPP21,NPAS3,NASP,SPART,VAMP1,PCDH11X,ZNF638,GPM6B,B4GALNT4,ZEB1,EML4,VSTM2A,GRIA2,CRB1,PTPN5,MFSD2A,CELF3,CDC42,PCDH8,CDH10,HRH3,MAGI1,PDE2A,PDE3B,PRMT8,CHGA,PFKFB3,MS4A7,SERPINE2,PIK3CD,BEST1,NSD2,NXPH1,MFSD4A,PPP3CB,OSBPL3,PRKACB,DOCK7,IGSF1,BRINP3,ANKS1B,PTHLH,PTPRE,RABGAP1L,TMCC2,DNAH9,KLRC2,PID1,SLC17A6,PLEKHB2,DSCAM,RFX4,JMJD1C,PHC2,SEC61A2" MicroRNA hsa-miR-96*:mirSVR_lowEffct hsa-miR-96*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.91E-34 2.12E-30 4.66E-33 4.28E-32 99 1771 "ACER3,MAP6,MBP,SYT9,LDLRAD3,RTN1,SLITRK1,ADD3,WAC,AMER2,GPR158,KIAA1109,BBOX1,FOXG1,SELL,ERICH3,APC,NTNG1,DGKD,SYBU,SHTN1,CCDC88A,DACH2,SLN,ASTN1,ZSWIM8,B4GALNT1,EMC1,SPART,NCAM1,ERBIN,NEUROD1,ZNF638,MYRF,BTRC,KLHL4,ANO4,CACNA1A,PRUNE2,PCDHGA3,VSTM2A,AKNA,GRIA1,GRIA2,GRID1,ATP13A2,INA,TMEM257,KCNK10,REPS2,C1orf94,DCLK1,LGI1,TPM4,PDE2A,PDE4B,PFKFB3,ZBED5,GDAP1L1,CADM1,NMT2,SULT4A1,PMP2,SPATA6,NSD2,FAT3,MFSD4A,POU3F2,CHD1L,CRLS1,SNCAIP,PPP3CB,KCNT2,ATRNL1,VCAN,PLPP4,HES5,EDRF1,KIAA0408,BRINP3,RIMS3,PTCH1,CNIH3,KCNA1,PCDH15,PEX5,GNE,FAM13C,DBX2,ST8SIA3,RGS10,ZNF248,TTLL7,SEC61A2,RNF220,RBM12,VWA5A,ARHGAP12,SLC4A10" MicroRNA hsa-miR-424:PITA hsa-miR-424:PITA_TOP PITA 4.19E-34 2.27E-30 4.99E-33 4.58E-32 66 754 "SYNDIG1,EYA1,SLITRK1,GALNT13,SCN3A,SCN4B,LRRC7,ELMOD1,CNIH2,SH3GL2,PPM1E,NLGN1,AQP4,SLC1A2,ARHGAP5,ARFGAP2,CSPG5,RCOR3,SNAP25,ATP2B2,SON,WDTC1,MYT1L,CAB39,LHFPL4,BCL2L2,DCAF5,VAMP1,SYT4,BTRC,WWC1,CACNA1E,CAMK2G,GRIN1,OMG,TGFBR3,PCDH9,DCLK1,PDE3B,ACOT7,CADM1,CAMKV,NSD2,FAT3,NXPH1,POU3F2,MED1,PPP2R5C,PPP3CB,OSBPL3,PTCH1,CSDE1,PTPRD,PEX5,PID1,TMEM255A,PAK5,BSDC1,ST8SIA3,SIDT2,PIANP,RBM12,ARHGAP12,EN2,TMEM100,EPB41L1" MicroRNA hsa-miR-302a:mirSVR_highEffct hsa-miR-302a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.21E-34 2.28E-30 5.01E-33 4.59E-32 90 1466 "EPS8,LGR4,MDM4,RTN1,WAC,AMER2,GPR158,SCN3A,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,ASPH,RCOR3,MEGF11,MYT1L,B3GALT2,TNIK,CAB39,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,SLCO1C1,ARHGEF7,ZNF638,CAMTA1,UNC5D,ADGRL3,GPM6A,CACNA1E,TCF7L2,ZEB1,SYT6,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,TGFBR3,P2RX7,AIFM1,HPS5,TNS1,C1orf94,PCDH9,PCSK2,MAGI1,PRMT8,BEST3,HMGB1,FAM181B,PRRX1,SPATA6,ACBD5,CNRIP1,SNCAIP,PPP3CB,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRDM2,PRTFDC1,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRO,RABGAP1L,PCDH15,KCNMA1,HS3ST4,FAM13C,DTNA,PAK5,SLC6A15,CRTAC1,TMEM100" MicroRNA hsa-miR-501-3p:mirSVR_lowEffct hsa-miR-501-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.31E-34 2.34E-30 5.11E-33 4.69E-32 81 1180 "ZFYVE27,LGR4,PAQR6,ADGRV1,MRVI1,RTN1,ADCY2,ADD3,ERMN,NLGN4X,TOMM40L,SCN3A,LINC00461,ASIC4,MOBP,SOX6,USP28,ITSN1,SYBU,NLGN1,CLSTN1,SLC7A14,NSG2,SMARCE1,SNAP25,ATP1A2,SON,WDTC1,MYT1L,JPH4,B4GALNT1,TTLL9,NFIA,CAMTA1,CAMSAP2,MYRF,WWC1,ANO4,GPM6A,GPM6B,AZIN2,TMEM151B,VSTM2A,GRIA1,TGFBR3,TJP1,DCLK1,PTGDR2,PFKFB3,DUSP26,ANLN,ST8SIA5,FLRT1,BTF3L4,MED1,MICAL2,OSBPL3,CHD5,RAB39A,USP54,NOS1AP,KIAA0408,PHYHIP,TOMM20,LRRTM3,CADM2,CNIH3,KCNA1,OLFM3,PTPRO,SRGAP3,ARNT2,KIF2A,KLRC2,TMEM255A,DTNA,ATL1,ARHGEF10L,RPRD1A,OLIG2,UEVLD" MicroRNA hsa-miR-802:mirSVR_lowEffct hsa-miR-802:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.43E-34 2.40E-30 5.24E-33 4.81E-32 100 1809 "TMEM74,MBP,RTN3,ARID1A,MDM4,CSMD3,SNX30,ADORA3,NLGN4X,FCGR1A,GPR158,LRRTM4,SEMA6A,SLC30A10,FOXG1,SOX6,CDC42BPA,PPM1E,SESN3,NTNG1,SHTN1,AQP4,ARFGAP2,SHANK2,ASCL1,SLCO1A2,SLIT1,NAXD,ASPH,ALDH4A1,ATM,SON,KIF21B,ZSWIM8,NMNAT2,SALL3,CPLX2,DNER,BCL2L2,ARHGEF7,PCDH11X,KAZN,CAMSAP2,BTRC,GOLGB1,KLHL4,GPM6B,VWC2,TCF12,NUDT21,EML4,CAMK2G,OPCML,TGFBR3,MFSD2A,REPS2,CDC42,PCDH8,RBFOX2,CIART,ADGRG1,CASC2,TMEFF2,CADM1,NRXN1,NEGR1,CCSER2,TJP2,FADS2,CHD1L,PPP2R5C,SNCAIP,MICAL2,OSBPL3,NCAN,DZIP3,FMN2,ECE2,TOX,TOMM20,PLPPR5,DNAJC6,ITGAV,PRDM2,PRTFDC1,CEP170,CSDE1,ZC3H11A,KCNA1,PTPRD,C1orf109,SRGAP3,DLG2,DLG3,KLRC3,SLC17A6,PLEKHB2,DTNA,ELAVL3,UEVLD" MicroRNA hsa-miR-1256:mirSVR_lowEffct hsa-miR-1256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.88E-34 2.64E-30 5.76E-33 5.28E-32 91 1502 "TTYH1,EPS8,ZFYVE27,ACER3,CDHR1,CEND1,MEG3,EYA1,SLC25A25,KLHL32,GRAMD1B,AMER2,CHST15,FGF1,BBOX1,UNC79,HPCAL4,MOBP,PKP4,PPM1E,APC,CCDC80,SORBS1,NLGN1,MIER1,RPH3A,LRRC55,NSG2,SLC14A1,PDE8B,SPHKAP,ASPH,EIF4G3,PALLD,SON,WDTC1,B3GALT2,SOX10,SALL3,NCAM1,RGL1,NEUROD1,ARHGEF7,LUZP2,DCLK2,KLHL4,TCF12,VXN,GRIA2,GRIA4,GPR88,CYB561A3,CRB1,TMEM25,TNFRSF1B,TNS1,LGI1,MAGI1,ZNF384,LINC01102,TUB,CADM1,KIAA1549L,SEMA5B,CNTN1,BEST1,IFFO1,NSD2,FAT3,CRLS1,FEZ2,ATRNL1,FMN2,CTNND2,ECE2,PLPPR5,CA10,PRDM2,KCNA4,SRGAP3,NTM,PCDH15,KCNMA1,NKAIN1,PID1,SLC25A48,DNM2,JMJD1C,SLC4A10,EPB41L2,RCAN2" MicroRNA hsa-miR-1826:mirSVR_highEffct hsa-miR-1826:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.21E-34 2.82E-30 6.13E-33 5.63E-32 82 1214 "RABEPK,EPS8,ADARB2,RTN1,GALNT13,CDC7,FABP7,NLGN4X,AGT,SCN3A,SCN4B,LRRC7,ERICH3,ANK3,ANXA7,DOCK10,CACHD1,ST3GAL3,API5,MSR1,DACH2,SPHKAP,SORCS3,SMARCE1,RCOR3,TMEM108,PHYHIPL,MEGF11,SON,MYT1L,KIF1B,GART,DNER,NPAS3,SPART,CLASP2,GANAB,ARHGEF7,DCLK2,CAMTA1,CACNB2,ZEB1,PTBP2,NUDT21,AKNA,GRIA1,GRIA2,GPR88,SPX,AIFM1,CDC42,PDYN,CA14,CASC2,NEGR1,TJP2,ST8SIA5,SLC25A27,SPATA6,NCAN,RBPJ,PRKAB2,PRKACB,DOCK7,EDRF1,ANKS1B,TUBB2B,HP1BP3,CSDE1,MAGI2,OCIAD1,KCNJ10,KCNMA1,NAV2,SNX27,DPP6,RFX4,JMJD1C,SSPN,SLC4A10,EPB41L2,RASGRP2" MicroRNA hsa-miR-595:mirSVR_lowEffct hsa-miR-595:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.38E-34 2.91E-30 6.32E-33 5.80E-32 99 1778 "EXTL1,MEG3,CLIP1,ADCY2,SLITRK1,WAC,CDC7,TOMM40L,HOGA1,ERICH3,CDC42BPA,ANK1,PKP4,PPM1E,APC,MAGI3,CCDC80,MIER1,URGCP,BCO1,RUFY2,ARHGAP5,CADPS,CGREF1,SCG3,SPHKAP,ASPH,TMEM108,EIF4G3,WDTC1,MYT1L,ENKUR,ADAM15,CPLX2,ADGRB2,NPAS3,NFASC,CLASP2,COLGALT2,ALDH1L1,ADHFE1,SEPT3,VAMP1,PCDH11X,ZNF638,KAZN,DDHD2,TMEM136,CACNA1E,PTBP2,CECR2,DDR2,NUMA1,GRIA1,GRIA2,GRIA4,CRB1,TMEM25,REPS2,CDC42,LINC01102,ZMYND8,FNDC5,CHGA,CASC2,PLXNB3,DOCK7,KIAA1755,PKN2,CTNND2,FAM131B,PROX1,KIAA0408,ZBTB16,TOMM20,CA10,BDNF-AS,PRDM2,LRP8,CEP170,PTPRE,SRGAP3,AK5,KCNJ9,KCNK1,DLG2,NKAIN1,KLRC2,TMEM255A,DNM2,RAP1GAP,RFX4,JMJD1C,ARHGEF10L,PHC2,SEC61A2,PIANP,ABI2,UEVLD" MicroRNA hsa-miR-567:mirSVR_highEffct hsa-miR-567:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.39E-34 2.92E-30 6.32E-33 5.80E-32 78 1093 "ACLY,CNTNAP3,ARID1A,RTKN,MDM4,CSMD3,CLIP1,GALNT13,LINC00461,KIAA1109,FGF1,LRRC7,MOBP,GPAM,SORBS1,MIER1,RUFY2,CCDC88A,SPHKAP,SMARCE1,RCOR3,ATP1A2,EIF4G3,PALLD,USP33,TNIK,DNER,NDUFA5,NEUROD1,DDHD2,GPM6B,ATF7,GRIA4,GRIK2,OLR1,CRB1,CDC42,PDE3B,BEST3,CASC2,TMEFF2,DUSP26,A2ML1,CNTN1,BEST1,BTF3L4,SPATA6,NKAIN4,OSBPL3,ATRNL1,RBPJ,DOCK7,PLD5,USP54,CTNND2,PUM1,ECE2,ANKS1B,TOMM20,SYNC,PTAFR,PTCH1,CA10,CADM2,CNIH3,MAGI2,KCNK2,DLG2,KIF2A,PLEKHB2,C12orf4,DBX2,JMJD1C,INSYN2,TTLL7,ARHGAP12,CBLN2,EPB41L2" MicroRNA hsa-miR-331-3p:mirSVR_lowEffct hsa-miR-331-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.74E-34 3.11E-30 6.71E-33 6.16E-32 78 1094 "DPF1,MAP6,ASIC1,FAM43B,SLITRK1,WAC,PNMA8B,NLGN4X,CHST15,TOMM40L,LRRTM4,LINC00461,SEMA6A,TRIM46,CNIH2,PPFIA1,SH3GL2,DGKZ,RPH3A,BCO1,PKNOX2,SLC6A9,TMEM151A,ZCCHC24,KIF21B,CADM3,ZSWIM8,NMNAT2,JPH4,ARPP21,EMC1,TTC9B,NFASC,ERBIN,NCDN,HEPN1,AJAP1,RHBDL3,PCDH11X,KAZN,ROBO3,MMD2,ADGRL3,DDR1,NUMA1,GRIA4,GRIK3,TMEM25,TGFBR3,USP2,PC,IGFN1,ZMYND8,FNDC5,HPCA,SLC22A6,TJP2,PLXNB3,C11orf49,NSD2,POU3F2,MICAL2,ECE2,PHYHIP,ZNF385B,LRRTM3,PTPRD,KCNA6,C1orf109,SV2A,RAB5B,SLC25A18,PHC2,SIDT2,EFNA3,ABI2,RPE65,PRRT4" MicroRNA "AAGCACA,MIR-218:MSigDB" "AAGCACA,MIR-218:MSigDB" MSigDB 6.31E-34 3.41E-30 7.36E-33 6.75E-32 49 370 "ASIC1,LGR4,RTN3,ATAT1,CSMD3,GALNT13,SORCS1,LRRC7,SEMA6A,PKP4,GPAM,SHTN1,SLC1A2,ARHGAP5,CCDC88A,SHANK2,B3GAT1,SOX5,KIF21B,LMO3,GNG3,ANO4,TBX15,GPM6A,GRIA2,GRIK2,GRIK3,TMEM25,GUCY1A2,ZFP91,PCDH8,NRXN1,NMT2,PTPA,RIMS4,PLD5,PUM1,BRINP3,RIMS3,ELMO1,CSDE1,MAGI2,OLFM3,PLPPR4,SV2A,RTN4,RET,RNF220,EPB41L1" MicroRNA hsa-miR-649:mirSVR_lowEffct hsa-miR-649:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.69E-34 3.62E-30 7.79E-33 7.15E-32 90 1475 "TTYH1,SYT9,LGR4,MEG3,ADGRV1,CSMD3,ERMN,TOMM40L,SEMA6A,MOBP,FOXG1,ITSN1,PPM1E,TACC2,BCAS1,ZNF365,SLC2A5,LRRC55,SLC8A2,DACH2,SLCO1A2,SPHKAP,NAXD,SMARCE1,ADGRA1,ATP2B2,SCN3B,USP33,SON,ZSWIM8,NMNAT2,TTLL9,NFASC,C11orf87,COLGALT2,DCAF5,NEUROD1,RND1,SEPT3,ARHGEF7,LUZP2,SEMA4A,MMD2,GOLGB1,KLHL4,TBX15,PRUNE2,PTBP2,NUDT21,CAMK2G,VSTM2A,GRIA1,GRIA2,OPCML,AIFM1,NEURL1,TPD52,TPM3,BEST3,CASC2,TLX1,ZFYVE9,KIAA1549L,NEGR1,A2ML1,ACBD5,POU3F2,CHD1L,MED1,CRMP1,CHD5,VCAN,NCAN,RBPJ,LRRTM3,PMEPA1,RGMA,PCDH15,NAV2,NKAIN1,GNE,DBX2,RET,FAM135B,RNF220,SIDT2,RPRD1A,EN2,TMEM100,EPB41L2" MicroRNA hsa-miR-218:mirSVR_highEffct hsa-miR-218:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.73E-34 3.64E-30 7.81E-33 7.17E-32 84 1281 "EPS8,LGR4,RTN3,MRVI1,CSMD3,ADARB2,GALNT13,SORCS1,MOG,ERICH3,PKP4,APBA2,SHTN1,LRRC55,CCDC88A,SHANK2,SPHKAP,NAXD,SLN,SORCS3,SMARCE1,B3GAT1,MYT1L,SOX5,LMO3,C11orf87,ERBIN,ZNF638,GNAS,NODAL,ANO4,GPM6A,TCF12,VXN,GRIA2,GRIA4,GRIK2,GPR88,GRM3,INA,GUCY1A2,TMEM257,PCDH8,PCDH9,TPD52,PDYN,HMGB1,JAM2,NRXN1,ANLN,NMT2,TJP2,ST8SIA5,SNCAIP,RGS6,ATRNL1,PKN2,PLD5,CTNND2,PUM1,EDRF1,MASP1,BRINP3,SPIRE1,CADM2,ELMO1,CSDE1,MAGI2,OLFM3,PLPPR4,KCNH1,SV2A,RABGAP1L,DLG2,CAB39L,KIF2A,SLC17A6,RTN4,INSYN2,ATL1,ZNF248,RNF220,OLIG2,UEVLD" MicroRNA hsa-miR-518c*:mirSVR_highEffct hsa-miR-518c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.76E-34 3.66E-30 7.83E-33 7.19E-32 80 1157 "SYT9,ACTN2,ATAT1,KCNIP2,CSMD3,TMEM156,NLGN4X,FCGR1A,TOMM40L,KIAA1109,LRRC7,BCAR3,MOBP,FOXM1,PPFIA1,MAGI3,CCDC80,CAPRIN2,ASPH,TMEM108,DKK3,KIF21B,ZSWIM8,AHCYL1,JPH4,TTLL9,NPAS3,COLGALT2,ERBIN,ARHGEF7,CASTOR3,PCDH11X,MMD2,BTRC,PSRC1,CNDP1,TBX15,CACNB2,ZEB1,TCF12,CRB1,USP2,FBXL16,TMEM257,PCDH9,SEZ6L,PRMT8,ZMYND8,NEGR1,ST8SIA5,FLRT1,CELF5,POU3F2,ETNPPL,SF1,DOCK7,PRKCG,PKN2,CTNND1,PUM1,EDRF1,ZNF385B,LRRTM3,CADM2,PRDM2,CSDE1,C1orf109,KCNK1,DLG2,OLIG1,RALGDS,BSDC1,ZYG11B,CAMK1G,RGS7,ZNF248,CBLN2,SLC4A10,RPE65,BAALC" MicroRNA hsa-miR-302b:mirSVR_highEffct hsa-miR-302b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.95E-34 3.76E-30 8.04E-33 7.38E-32 91 1509 "EPS8,LGR4,MDM4,RTN1,WAC,AMER2,GPR158,SCN3A,SGIP1,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,YPEL4,SLC14A1,ASPH,RCOR3,MEGF11,MYT1L,B3GALT2,TNIK,CAB39,ARPP21,LMO3,CLASP2,DCAF5,RGL1,NEUROD1,SLCO1C1,ARHGEF7,ZNF638,CAMTA1,UNC5D,ADGRL3,GPM6A,ZEB1,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,TGFBR3,AIFM1,HPS5,TNS1,C1orf94,PCDH9,PCSK2,MAGI1,PRMT8,HMGB1,ST8SIA5,FAM181B,PRRX1,SPATA6,ACBD5,CNRIP1,SNCAIP,PPP3CB,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRDM2,PRTFDC1,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRO,RABGAP1L,PCDH15,KCNMA1,HS3ST4,SLC17A6,FAM13C,DTNA,PAK5,SLC6A15,CRTAC1,RET,TMEM100" MicroRNA hsa-miR-936:mirSVR_lowEffct hsa-miR-936:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.09E-34 3.84E-30 8.19E-33 7.51E-32 97 1714 "ASIC1,EYA1,ATAT1,CSMD3,CDC7,SLC44A5,LRRTM4,FGF1,FGF14,FHL1,GOLGA7B,MOG,SOX6,ANK2,ANK3,APBA2,NTNG1,TACC2,AQP4,MADD,LRRC55,SHANK2,DACH2,SPHKAP,SLIT1,KBTBD12,ALDH4A1,NRG3,WDTC1,EMC1,TTLL9,DNER,NPAS3,C11orf87,COLGALT2,PCDH11X,LUZP2,NODAL,MMD2,PSRC1,ATF7,ACSL6,CACNB2,EML4,CAMK2A,GRID1,GRM3,P2RX7,TJP1,MAEL,PAX6,REPS2,HPS5,CDC42,PDYN,ADGRG1,HMGB1,PFKFB3,MS4A7,HEPACAM,SERPINE2,NEGR1,ANLN,PIK3CD,CCSER2,CNRIP1,PPP2R5C,SNCAIP,FEZ2,OSBPL3,RBPJ,PLPP4,BRINP3,PHYHIP,TOMM20,PLPPR5,PTAFR,PTCH1,STMN4,ZC3H11A,KCNA1,PLPPR4,KCND3,KCNJ11,KCNK1,NKAIN1,FAM57B,RALGDS,DTNA,ZYG11B,RET,RFX4,RNF220,SSPN,PIANP,RPRD1A,EPB41L2" MicroRNA hsa-miR-323b-3p:mirSVR_lowEffct hsa-miR-323b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.31E-34 3.96E-30 8.42E-33 7.73E-32 91 1510 "RABEPK,TTYH1,CNTNAP3,IL17D,CSMD3,SLITRK1,ADD3,ERMN,KIAA1109,FGF1,FGF14,SFPQ,ERICH3,ANK3,FOLH1,ANXA7,PPM1E,TACC2,SORBS1,SYBU,SHTN1,AQP4,ZNF365,SLC1A6,BCO1,CCDC88A,PDE8B,ASPH,PHYHIPL,MYT1L,AHCYL1,ARPP21,NCAM1,LMO3,NEUROD1,SLCO1C1,VAMP1,DCLK2,KAZN,CAMSAP2,TMEM136,CACNB2,ZEB1,PTBP2,GRIA2,GRIA4,GRIK2,TJP1,CELF3,CDC42,ARHGAP19,PDE3B,PDE4B,TMEFF2,SERPINE2,ST8SIA5,NSD2,NXPH1,POU3F2,PPP2R5C,SNCAIP,CSF3R,RBPJ,DOCK7,RAB39A,NRSN1,NOS1AP,KIAA0408,WBP1L,SPIRE1,PTCH1,PLPPR1,BDNF-AS,PRDM2,LRP8,ZC3H11A,PTPRD,PLPPR4,C1orf109,PTPRZ1,KCNK2,ABI1,RTN4,RFX4,ZNF248,SEC61A2,GPR61,ABI2,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-302d:mirSVR_highEffct hsa-miR-302d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.20E-34 4.44E-30 9.43E-33 8.65E-32 90 1479 "EPS8,SYT9,LGR4,MDM4,RTN1,WAC,AMER2,GPR158,SCN3A,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,ASPH,RCOR3,MEGF11,MYT1L,B3GALT2,TNIK,CAB39,ARPP21,LMO3,CLASP2,DCAF5,RGL1,NEUROD1,SLCO1C1,ARHGEF7,ZNF638,CAMTA1,UNC5D,ADGRL3,GPM6A,CACNA1E,ZEB1,SYT6,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,TGFBR3,AIFM1,HPS5,TNS1,PCDH9,PCSK2,MAGI1,PRMT8,BEST3,HMGB1,FAM181B,PRRX1,SPATA6,ACBD5,CNRIP1,PPP2R5C,SNCAIP,PPP3CB,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRDM2,PRTFDC1,HP1BP3,RGMA,MAGI2,BLOC1S6,ZC3H11A,OLFM3,PTPRO,RABGAP1L,KCNMA1,HS3ST4,FAM13C,DTNA,PAK5,SLC6A15,CRTAC1,TMEM100" MicroRNA hsa-miR-4320:mirSVR_lowEffct hsa-miR-4320:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.37E-34 4.53E-30 9.61E-33 8.81E-32 87 1381 "LGR4,RTN3,RCSD1,ADGRV1,ATAT1,ADAR,ADCY2,ADD3,SCN3A,ASRGL1,ITSN1,APC,MAGI3,GPAM,ST3GAL3,SHTN1,AQP4,MIER1,DACH2,TAGLN3,B3GAT1,ALDH4A1,SNAP25,NRG3,GABBR1,SOX10,CLASP2,COLGALT2,STOX1,NCDN,SLCO1C1,GLS,CASTOR3,PCDH11X,SYT4,KAZN,ADGRL3,TMEM136,TBX15,CACNA1A,CACNB2,EML4,CAMK2G,NUMA1,BRSK2,GRIK2,OLR1,TLL2,PADI2,DCLK1,TPM3,TPM4,PDE3B,ANO5,ZBED5,HEPACAM,NLGN3,NRXN1,CCSER2,FTO,VAV2,NSD2,FAAP20,POU3F2,MED1,SNCAIP,RGS6,FEZ2,RBPJ,FMN2,NOS1AP,ZNF385B,SIRPA,BDNF-AS,PTPRD,SMG7,ARNT2,PCDH15,NAV2,SNX27,TMEM255A,SLC25A48,SLC17A6,DTNA,BSDC1,RGS7,EN2" MicroRNA hsa-miR-1914:mirSVR_lowEffct hsa-miR-1914:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.31E-34 5.04E-30 1.07E-32 9.78E-32 87 1383 "TTYH1,MAP6,PAQR6,CEND1,MEG3,ADGRV1,NDRG2,KLHL32,SORCS1,NLGN4X,ASIC4,BCAR3,ERICH3,SH3GL2,CCDC80,ZCCHC17,NLGN1,ST3GAL3,SHTN1,MSR1,ARHGAP5,NSG2,DACH2,GPR153,BRINP2,SORCS3,ASTN1,PALLD,DKK3,NMNAT2,TTLL9,FXYD6,BCL2L2,GPR162,ERBIN,FAM168A,ARHGEF7,GLS,LUZP2,GNAS,PRUNE2,WSCD1,FAM69C,VXN,TJP1,PCSK2,PDE2A,PDE4B,HMGB1,TLX1,HEPACAM,CPT1C,MEAF6,PRRX1,VCAN,KIAA1755,CTNND2,DPYSL5,ANKS1B,PLPPR1,LRP8,ZC3H11A,SV2A,KCNJ9,RABGAP1L,KCNJ10,CCDC3,KCNN3,DLG2,DLG3,KIF2A,RAB5B,DPP6,DSCAM,DTNA,CRTAC1,NUP214,RGS7,FAM135B,INSYN2,ZNF248,ARHGAP12,RAVER2,SLC4A10,EPB41,EPB41L2,RCAN2" MicroRNA hsa-miR-2113:mirSVR_highEffct hsa-miR-2113:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.33E-34 5.05E-30 1.07E-32 9.78E-32 79 1132 "EPS8,CNTNAP3,RTN3,EYA1,MRVI1,ADARB2,KLRC4,SLITRK1,SORCS1,SCN3A,SOX6,PKP4,GPAM,SORBS1,RUFY2,MSRA,ARHGAP5,CCDC88A,SLN,SORCS3,TMEM151A,ATP1A2,EIF4G3,MYT1L,B3GALT2,TNIK,TTLL9,KIF1B,LMO3,STOX1,ERBIN,RGL1,PCDH11X,ZNF638,KAZN,SEMA4A,CAMTA1,ADGRL3,TMEM136,PRUNE2,CACNA1E,TCF12,CAMK2G,GRIK2,GRM3,OMG,LINC00839,GUCY1A2,TPD52,MAGI1,ZMYND8,FNDC5,HMGB1,TMEFF2,NLGN3,CCSER2,TJP2,PMP2,POU3F2,RBPJ,PKN2,USP54,LRRTM3,PMEPA1,BDNF-AS,ELMO1,CEP170,CSDE1,MAGI2,KCNH1,NTM,CAB39L,WIPF2,SLC17A6,C12orf4,CRTAC1,ATL1,RPRD1A,OLIG2" MicroRNA hsa-miR-4295:mirSVR_highEffct hsa-miR-4295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-33 5.55E-30 1.17E-32 1.07E-31 80 1164 "CNTNAP3,MDM4,CSMD3,F3,CLIP1,RTN1,GALNT13,WAC,GPR158,TESK2,SCN3A,MOG,ERICH3,USP28,APC,NTNG1,SLITRK3,SYBU,API5,AQP4,MIER1,BCO1,RUFY2,CCDC88A,SHANK2,NAXD,CAPRIN2,MTR,SNAP25,USP33,MYT1L,SOX5,B4GALNT1,TTLL9,TTC9B,SPART,SMOC1,ERBIN,NEUROD1,GLS,CAMTA1,CAMSAP2,PRUNE2,ZEB1,SYT6,OMG,LINC00839,ZFP91,TNS1,PDE1C,PDE3B,HMGB1,ZFYVE9,KIAA1549L,CCSER2,ST8SIA5,BTF3L4,ACBD5,POU3F2,CRLS1,CHD5,ARHGEF4,NRSN1,PSD,PLPPR1,PMEPA1,PTHLH,LRP8,CEP170,KCNN3,CAB39L,RAB5B,PID1,ATG16L1,C12orf4,ABCC9,RET,SLC39A12,RPRD1A,ARHGAP12" MicroRNA hsa-miR-4293:mirSVR_lowEffct hsa-miR-4293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-33 5.64E-30 1.18E-32 1.09E-31 82 1226 "TTYH1,ACTN2,ADGRV1,IL17D,ATAT1,KLHL32,RXRG,NLGN4X,LRRTM4,TRIM46,SFPQ,ASRGL1,RASA3,USP28,SESN3,MAGI3,AQP4,ZNF365,SFMBT2,SLC6A9,ARFGAP2,NSG2,SNAP25,SON,ENKUR,NEK6,IDI2-AS1,NAP1L2,NPAS3,DCAF5,INKA2,ARHGEF7,ZNF638,LUZP2,NODAL,CNTN2,GPR17,PTBP2,CECR2,TMEM151B,VXN,GRIK2,ADAMTS8,LEFTY2,GUCY1A2,LGI1,TPM3,ZNF384,ANO5,PLEKHB1,SEMA5B,CCSER2,FLRT1,FTO,C11orf49,MEAF6,BTF3L4,PTPA,SNCAIP,PHACTR3,PRKAB2,CMTM5,CTNND1,MASP1,SIRPA,ITGAV,CNIH3,KCNA1,PTPRD,KCNA6,RABGAP1L,DLG2,RALGDS,SUSD4,DSCAM,DBX2,BSDC1,CBLN2,BSCL2,EPB41L1,EPB41L2,SEZ6" MicroRNA hsa-miR-296-3p:mirSVR_lowEffct hsa-miR-296-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-33 5.76E-30 1.21E-32 1.11E-31 89 1451 "ZFYVE27,ARID1A,WAC,TOMM40L,SNX32,TESK2,SEMA6A,FGR,FHL1,ITSN1,BCAN,NLGN1,JAKMIP3,PAAF1,MIER1,LRRC55,ASCL1,CGREF1,NAXD,B3GAT1,GABBR1,SON,KIF21B,CAB39,NMNAT2,ENKUR,ADGRB2,CLASP2,KIRREL3,ADHFE1,ARHGEF7,ZNF638,KAZN,PSRC1,KLHL4,ANO4,CACNA1E,LRIT2,TCF12,NUMA1,AKNA,GRIA1,GRIA2,RFFL,OLR1,OPCML,FBXL16,P2RX7,DAAM2,HPS5,CDC42,PADI2,DCLK1,SEZ6L,TPM3,PDE1A,LINC01102,ZMYND8,BEST3,HMGB1,PLEKHB1,NLGN3,NRXN2,SULT4A1,SLC25A27,BTF3L4,ATCAY,MED1,PNKD,SDC3,PKN2,BRINP3,KLK6,SYTL2,SYNC,PRDM2,COPS7A,STMN4,PTPRE,SV2A,TMCC2,DLG2,SLC25A48,FAM66C,ARHGEF10L,ARHGAP12,YY1AP1,OLIG2,EPB41L1" MicroRNA hsa-miR-606:mirSVR_lowEffct hsa-miR-606:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-33 6.36E-30 1.33E-32 1.22E-31 86 1355 "ACER3,CNTNAP3,LGR4,LDLRAD3,CSMD3,RTN1,FABP7,LRRTM4,LRRC7,ERICH3,USP28,PPM1E,NTNG1,GPAM,CACHD1,AQP4,LRRC55,ARHGAP5,DACH2,RCOR3,IGSF9B,ATM,ZCCHC24,GAD2,DNER,NAP1L2,NPAS3,C11orf87,NEUROD1,ARHGEF7,GLS,VAMP1,LUZP2,PRUNE2,GPM6B,CACNB2,ZEB1,AZIN2,GRIA2,GRIA4,GRID1,GPR88,CRB1,TMEM9,AIFM1,REPS2,DCLK1,RBFOX2,LGI1,PCSK2,BEST3,HMGB1,SCRG1,JAM2,SERPINE2,CCSER2,ACBD5,RNF14,CRLS1,SNCAIP,OSBPL3,PRKACB,FMN2,PKN2,FGFR1OP2,DPYSL5,ANKS1B,SPIRE1,SYNC,DNAJC6,ITGAV,CADM2,PRDM2,HP1BP3,LRP8,MAGI2,KCNA4,SMG7,DLG3,FAM135B,SEC61A2,RBM12,SH3GLB1,ABI2,SLC4A10,RPE65" MicroRNA hsa-miR-134:mirSVR_lowEffct hsa-miR-134:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-33 6.36E-30 1.33E-32 1.22E-31 93 1587 "ACER3,ASIC1,LDLRAD3,KLHL32,RXRG,AMER2,TOMM40L,HOGA1,TESK2,LRRTM4,FGF1,BBOX1,ELMOD1,FOXM1,CNIH2,PPM1E,GPAM,BCAS1,CCDC88A,SLIT1,KBTBD12,PALLD,DKK3,ENKUR,TTLL9,ADAM15,SPART,NCAM1,NDUFA5,STOX1,NEUROD1,FAM168A,ARHGEF7,ADGRL3,NUDT21,NUMA1,GRIA1,GRIA2,GPR88,OPCML,TGFBR3,INA,TMEM257,KCNK10,DAAM2,TNFRSF1B,PCDH9,CDH8,SEZ6L,PCSK2,PDE4B,ACOT7,TMPRSS5,HPSE2,ANO5,KIAA1549L,CAMKV,NEGR1,ANLN,OPALIN,FTO,CCDC136,IFFO1,NSD2,CSF3R,VCAN,SDC3,PLD5,ARHGEF4,HES5,KIAA0408,BRINP3,SYTL2,PHYHIP,SYNC,DNAJC6,MAGI2,KCNA4,KCNA6,DLG2,NKAIN1,PID1,SLC25A48,FAM66C,RALGDS,RASGRF1,DTNA,NUP214,RFX5,RGS7,ARHGEF10L,ARHGAP12,ELAVL3" MicroRNA hsa-miR-592:mirSVR_highEffct hsa-miR-592:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.28E-33 6.92E-30 1.44E-32 1.32E-31 78 1107 "TTYH1,WLS,CLIP1,FABP7,SORCS1,ERMN,GPR158,LINC00461,PLA2G6,LRRC7,ELMOD1,SLC30A10,ANK3,PPM1E,MAGI3,LRRC4C,SPHKAP,SMARCE1,RCOR3,SNAP25,ZCCHC24,TTLL9,KIF1B,LMO3,C11orf87,NDUFA5,KIRREL3,ARHGEF7,RHBDL3,LUZP2,UNC5D,ADGRL3,ANO4,PRUNE2,GPM6B,ACSL6,CCKBR,TJP1,TMEM257,PAX6,C1orf94,PCDH9,TPM3,MAGI1,PDE1C,PDE3B,PRMT8,CASC2,A2ML1,TJP2,CNRIP1,CP,CRMP1,CRLS1,KCNT2,FEZ2,MICAL2,NCAN,FMN2,PKN2,ARHGEF4,NRSN1,ANKS1B,PLPPR5,PTHLH,STMN4,BLOC1S6,KCNA2,PTPRD,RABGAP1L,PEX5,SLC25A18,SUSD4,FAM13C,ABCC9,SLC6A15,SEC61A2,RNF220" MicroRNA hsa-miR-4265:mirSVR_lowEffct hsa-miR-4265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-33 7.43E-30 1.54E-32 1.42E-31 88 1423 "PRR5L,ZFYVE27,MBP,EYA1,FAM43B,ATAT1,WLS,DSCAML1,SLITRK1,ADORA1,ADORA3,GPR158,FGF1,ASIC4,SELL,ANK3,RASA3,CNIH2,APBB1,ST3GAL3,KIAA1614,MADD,PKNOX2,SLC6A9,LGI3,SMARCE1,KBTBD12,B4GALNT1,ADGRB2,NCAM1,ALDH1L1,SMOC1,KIRREL3,SEPT3,ZNF638,GNAS,TBX15,PRUNE2,NUCB1,GRID1,CYB561A3,OPCML,TMEM9,TNFRSF1B,TPM4,MAGI1,PRMT8,SCRG1,TLX1,KIAA1549L,PIK3CD,UBTF,NMT2,CCSER2,OPALIN,VAV2,CELF5,PRRX1,SPATA6,PACSIN1,NSD2,FAT3,PNKD,RGS6,KCNT2,ATRNL1,SDC3,PLPP4,USP54,ARHGEF4,NRSN1,ECE2,MASP1,DPYSL5,PHYHIP,SMG7,KCNMA1,RALGDS,RASGRF1,GNE,ZNF248,SEC61A2,SFXN5,SSPN,CACNG7,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-125b:mirSVR_lowEffct hsa-miR-125b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.38E-33 7.45E-30 1.55E-32 1.42E-31 89 1456 "ABAT,MAP6,ACHE,EMID1,SYT9,MEG3,PLEKHG5,ERMN,FCGR1A,SNX32,ASIC4,MOBP,PI16,ITSN1,PKP4,APC,MAGI3,DGKZ,API5,ARFGAP2,DACH2,GPR153,SLCO1A2,LGI3,C10orf105,NRG3,WDTC1,ENKUR,B4GALNT1,NFASC,NCDN,ADHFE1,GLS,ZNF638,GNAS,GOLGB1,TMEM136,CACNA1E,DDR1,DIRAS1,CECR2,GRIA2,TF,CRB1,PADI2,CDH8,PTGDR2,HRH3,PDE3B,CASC2,KIAA1549L,NRXN1,CAMKV,OPALIN,FADS2,MFSD4A,POU3F2,PTPA,PPP2R5C,TENM4,NCAN,PRKCZ,MAPK10,FAM131B,ECE2,NOS1AP,PROX1,PSMD13,PRDM2,CSDE1,ZC3H11A,KCNA1,PTPRD,PTPRE,C1orf109,SV2A,PCDH15,CAB39L,WIPF2,PARP11,GOPC,DTNA,SLC6A15,RET,FAM135B,PHC2,ZNF248,SYT15,VWA5A" MicroRNA hsa-miR-2053:mirSVR_highEffct hsa-miR-2053:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-33 7.67E-30 1.59E-32 1.46E-31 103 1943 "ABAT,LOC100128239,SYT9,LGR4,ACTN2,CSMD2,MDM4,CLIP1,KLHL32,SLITRK1,WAC,CDC7,FABP7,ERMN,TMEM156,SCN3A,LINC00461,KIAA1109,FHL1,SLC30A10,PPFIA1,APC,NTNG1,MAGI3,SLITRK3,NLGN1,LRRC4C,SHTN1,ZNF365,RUFY2,MSR1,ASPH,NRG3,PHYHIPL,B3GALT2,GAD2,AHCYL1,JPH4,ARPP21,EMC1,C11orf87,CLASP2,LUZP2,GNAS,CAMSAP2,ADGRL3,KLHL4,GPM6B,LRIT2,TCF7L2,ZEB1,PTBP2,NUMA1,GRIA2,GRM3,OLR1,ZFP91,HPS5,PCDH9,TPD52,PDE4B,CASC2,PMP2,SLC36A4,CP,PPP3CB,FEZ2,DZIP3,RAB39A,CTNND2,PUM1,SYTL2,GON4L,SPIRE1,ZNF385B,LRRTM3,PSMD13,PLPPR1,JAKMIP2,PRDM2,LRP8,BLOC1S6,ZC3H11A,PTPRO,PTPRZ1,SRGAP3,KCNK1,TMEM255A,RAD52,FAM66C,SUSD4,ABI1,FAM13C,DBX2,DTNA,INSYN2,RPRD1A,LPAR6,SLC4A10,ELAVL4,RPE65,RCAN2,BAALC" MicroRNA hsa-miR-29c-3p:TargetScan hsa-miR-29c-3p TargetScan 1.49E-33 8.06E-30 1.66E-32 1.52E-31 71 906 "ASIC1,PAQR6,ACTN2,LDLRAD3,KCNIP2,ADCYAP1R1,CDC7,GRAMD1B,MOG,CDC42BPA,ANK1,ANK3,PPM1E,APC,GAS7,GPAM,DGKD,AQP4,CCDC88A,LGI3,ATP2B2,SCN3B,ILDR2,NPAS3,NASP,C11orf87,BCL2L2,NFIA,CAMSAP2,MMD2,CACNA1A,DIRAS1,EML4,CAMK2G,INA,KCNK10,DAAM2,REPS2,CDC42,PCDH9,RBFOX2,FNDC5,HEPACAM,NLGN3,KIAA1549L,NEGR1,CCSER2,IFFO1,OSBPL3,PRKAB2,ARHGEF4,IGSF1,CTNND1,NRSN1,MAPK8,MAPK10,FAM131B,DPYSL5,PTHLH,PTPRD,NAV2,PEX5,DLG2,NKAIN1,FAM57B,GOPC,BSDC1,JMJD1C,ELAVL4,PRRT4,EPB41L1" MicroRNA hsa-miR-29a-3p:TargetScan hsa-miR-29a-3p TargetScan 1.49E-33 8.06E-30 1.66E-32 1.52E-31 71 906 "ASIC1,PAQR6,ACTN2,LDLRAD3,KCNIP2,ADCYAP1R1,CDC7,GRAMD1B,MOG,CDC42BPA,ANK1,ANK3,PPM1E,APC,GAS7,GPAM,DGKD,AQP4,CCDC88A,LGI3,ATP2B2,SCN3B,ILDR2,NPAS3,NASP,C11orf87,BCL2L2,NFIA,CAMSAP2,MMD2,CACNA1A,DIRAS1,EML4,CAMK2G,INA,KCNK10,DAAM2,REPS2,CDC42,PCDH9,RBFOX2,FNDC5,HEPACAM,NLGN3,KIAA1549L,NEGR1,CCSER2,IFFO1,OSBPL3,PRKAB2,ARHGEF4,IGSF1,CTNND1,NRSN1,MAPK8,MAPK10,FAM131B,DPYSL5,PTHLH,PTPRD,NAV2,PEX5,DLG2,NKAIN1,FAM57B,GOPC,BSDC1,JMJD1C,ELAVL4,PRRT4,EPB41L1" MicroRNA hsa-miR-29b-3p:TargetScan hsa-miR-29b-3p TargetScan 1.49E-33 8.06E-30 1.66E-32 1.52E-31 71 906 "ASIC1,PAQR6,ACTN2,LDLRAD3,KCNIP2,ADCYAP1R1,CDC7,GRAMD1B,MOG,CDC42BPA,ANK1,ANK3,PPM1E,APC,GAS7,GPAM,DGKD,AQP4,CCDC88A,LGI3,ATP2B2,SCN3B,ILDR2,NPAS3,NASP,C11orf87,BCL2L2,NFIA,CAMSAP2,MMD2,CACNA1A,DIRAS1,EML4,CAMK2G,INA,KCNK10,DAAM2,REPS2,CDC42,PCDH9,RBFOX2,FNDC5,HEPACAM,NLGN3,KIAA1549L,NEGR1,CCSER2,IFFO1,OSBPL3,PRKAB2,ARHGEF4,IGSF1,CTNND1,NRSN1,MAPK8,MAPK10,FAM131B,DPYSL5,PTHLH,PTPRD,NAV2,PEX5,DLG2,NKAIN1,FAM57B,GOPC,BSDC1,JMJD1C,ELAVL4,PRRT4,EPB41L1" MicroRNA hsa-miR-122:mirSVR_lowEffct hsa-miR-122:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-33 8.22E-30 1.69E-32 1.55E-31 83 1264 "ASIC1,SYNDIG1,ATAT1,CSMD2,SORCS1,HOGA1,MOBP,SOX6,ANK2,PPM1E,APBA2,NTNG1,GPAM,SLC7A14,SLC1A7,YPEL4,MTR,KBTBD12,ATP1A2,SCN3B,NMNAT2,MYH7,ENKUR,ARPP21,KIF1B,DNER,NASP,NCAM1,SEPT3,GLS,RHBDL3,PCDH11X,KAZN,SEMA4A,DDR1,CACNB2,AZIN2,CECR2,DDR2,AKNA,ATP13A2,OLR1,OPCML,FBXL16,GUCY1A1,CELF3,TMEM257,ZDHHC22,KCNK10,TNFRSF1B,PDE1A,PDE1C,BEST3,HMGB1,HPSE2,CHGA,ARHGAP22,NLGN3,NEGR1,ST8SIA5,P2RY12,SLC36A4,RGS6,PRKCZ,CA10,PMEPA1,ELMO1,PTPRO,PTPRZ1,SRGAP3,KCNJ10,ARNT2,DLG2,DLG3,PLEKHB2,ATN1,DSCAM,ZYG11B,RFX4,INSYN2,LPAR6,EPB41L2,RCAN2" MicroRNA hsa-miR-196a*:mirSVR_highEffct hsa-miR-196a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-33 9.27E-30 1.90E-32 1.74E-31 71 908 "ATAT1,LDLRAD3,ARID1A,NDRG2,WAC,ERMN,ADORA3,LRRTM4,FHL1,PDZD4,ERICH3,ASRGL1,ANK2,PKP4,APC,MIER1,CCDC88A,SORCS3,SMARCE1,DKK3,ARPP21,NPAS3,NDUFA5,GPR162,NEUROD1,NKX2-2,GPM6B,ATF7,NPPA,CACNB2,ZEB1,TCF12,CECR2,TMEM151B,GRIK2,TF,CELF3,PADI2,DCLK1,MAGI1,ZMYND8,NTSR2,CHI3L2,TMEFF2,NRXN1,PMP2,ACBD5,PPP3CB,KCNT2,NRSN1,SYTL2,SPIRE1,TOMM20,LRRTM3,PTHLH,HP1BP3,STMN4,PLPPR4,AK5,RABGAP1L,KCNMA1,DLG2,ATN1,CRTAC1,JMJD1C,SEC61A2,PIANP,RPRD1A,ABI2,SLC4A10,ELAVL4" MicroRNA hsa-miR-19b-1*:mirSVR_highEffct hsa-miR-19b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-33 9.35E-30 1.91E-32 1.76E-31 84 1298 "ACER3,SYT9,RTN3,ARID1A,CSMD3,RTN1,SORCS1,TOMM40L,SEMA6A,MOG,ERICH3,ANK3,USP28,SH3GL2,GPAM,API5,SHTN1,RCOR3,EIF4G3,PHYHIPL,PALLD,B3GALT2,SOX5,CAB39,GAD2,NAP1L2,NPAS3,RGL1,ZNF638,CAMTA1,ADGRL3,ZEB1,PTBP2,CAMK2G,VSTM2A,GRIK2,CRB1,PTPN5,P2RX7,CDH8,TPM4,PDE1C,CHGA,CASC2,TUB,TMEFF2,JAM2,NLGN3,NRXN1,NEGR1,CCSER2,P2RY12,SLC36A4,NSD2,MFSD4A,CP,POU3F2,KCNT2,FEZ2,MICAL2,PLCH2,CTNND1,MAPK10,ANKS1B,SPIRE1,CA10,PRDM2,CEP170,CSDE1,MAGI2,PTPRD,AK5,KCNK2,KCNN3,TMEM255A,SLC17A6,ABI1,DTNA,RNF220,SSPN,VWA5A,SLC4A10,ELAVL4,RPE65" MicroRNA hsa-miR-3130-3p:mirSVR_lowEffct hsa-miR-3130-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.73E-33 9.37E-30 1.91E-32 1.76E-31 93 1595 "LOC100128239,APC2,CNTNAP3,SYT9,CSMD2,RTKN,TMEM156,HOGA1,FGF1,MOBP,FOXG1,CDC42BPA,CNIH2,SH3GL2,PPM1E,SLITRK3,API5,AQP4,LRRC55,ARFGAP2,MT3,SMARCE1,ADGRA1,WDTC1,TNIK,ZSWIM8,NMNAT2,IDI2-AS1,KIF1B,GART,DNER,RAP1GAP2,PHLDB1,RND1,PCDH11X,POPDC3,GNAS,BTRC,CNTN2,GPM6A,GPM6B,HAP1,PTBP2,BRSK2,GRIA1,ADAMTS8,ATP13A2,OPCML,SPX,HPS5,PCDH8,LILRA4,HMGB1,HERC2P3,PIK3CD,CCSER2,MED1,CRLS1,PTPA,SNCAIP,PPP3CB,FEZ1,ATRNL1,VCAN,PRKACB,DZIP3,DPYSL5,GON4L,TOMM20,PSMD13,SIRPA,PTAFR,KCNA4,CDH20,KCNA6,SMG7,C1orf109,ARNT2,NKAIN1,OLIG1,RAB5B,SLC25A48,RET,RGS7,TTLL7,SEC61A2,RNF220,PIANP,SH3GLB1,RPRD1A,ELAVL4,EPB41L1,LRRC23" MicroRNA hsa-miR-4329:mirSVR_lowEffct hsa-miR-4329:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.03E-33 1.10E-29 2.24E-32 2.05E-31 98 1772 "EPS8,ZFYVE27,ASIC1,ACHE,LDLRAD3,NDRG2,KLHL32,ERMN,FCGR1A,LINC00461,SLC30A10,MOBP,ERICH3,SGIP1,CDC42BPA,NLGN1,ST3GAL3,LRRC55,SLC8A2,YPEL4,ASCL1,ASPH,SORCS3,ATM,FYN,ENKUR,KIF1B,ADGRB2,NFASC,NCAM1,C11orf87,BCL2L2,GFAP,ADHFE1,ARHGEF7,ZNF638,DDHD2,CAMSAP2,BTRC,ADGRL3,KLHL4,WSCD1,CACNA1E,PTBP2,EML4,PCDHGA3,TMEM151B,VXN,NUMA1,BRSK2,GRM3,CRB1,INA,TMEM9,CDC42,CDH10,PDE2A,PRMT8,LINC01102,PDYN,HMGB1,CA14,ZBED5,HPCA,HEPACAM,A2ML1,FTO,SULT4A1,MEAF6,SLC36A4,PACSIN1,PPP3CB,KCNT2,MICAL2,PKN2,NRSN1,SPIRE1,TOMM20,PLPPR1,PRDM2,PRTFDC1,MAGI2,OCIAD1,SMG7,PTPRO,NTM,KCNJ10,KCNJ11,PCDH15,NAV2,NKAIN1,RAB5B,KLRC2,DNM2,FAM66C,ZYG11B,RET,JMJD1C" MicroRNA hsa-miR-3182:mirSVR_highEffct hsa-miR-3182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.04E-33 1.10E-29 2.24E-32 2.06E-31 84 1301 "RABEPK,ACER3,CDHR1,RTN3,RCSD1,MRVI1,MDM4,CSMD3,GRAMD1B,FCGR1A,CHST15,USP28,PKP4,APC,MAGI3,BCAS1,ZNF365,MIER1,ASPH,SORCS3,SMARCE1,EIF4G3,MEGF11,ILDR2,AHCYL1,NMNAT2,JPH4,ZNF302,ADHFE1,GLS,ZNF638,NODAL,PRUNE2,VWC2,NPPA,CLEC9A,GPR19,TCF12,EML4,VSTM2A,GRIA2,GRIK2,TMEM25,ZFP91,TPM4,ZMYND8,TMPRSS5,LRTM2,A2ML1,CELF5,P2RY12,CHD1L,MED1,TENM4,KCNT2,PHACTR3,PRKACB,ARHGEF4,CTNND2,PUM1,PROX1,ZBTB16,ZNF385B,PTCH1,LRP8,SMG7,KCNK2,PCDH15,DLG2,HS3ST4,DNAH9,C12orf4,DBX2,DTNA,ABCC9,SLC6A15,ZYG11B,INSYN2,PHC2,RBM12,RPRD1A,RAVER2,ELAVL3,RCAN2" MicroRNA hsa-miR-500*:mirSVR_lowEffct hsa-miR-500*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.12E-33 1.15E-29 2.33E-32 2.14E-31 83 1270 "SERPINA3,LOC100128239,ZFYVE27,ACER3,SYT9,RCSD1,CSMD2,SORCS1,ADORA3,GPR158,TESK2,LRRC7,ASIC4,FHL1,MOG,ANK1,RASA3,USP28,ITSN1,NTNG1,MAGI3,GPAM,BCAN,BCAS1,RPH3A,SLC14A1,SORCS3,ADGRA1,WDTC1,B3GALT2,KIF1B,NPAS3,NFASC,ALDH1L1,PCDH11X,KLHL4,TBX15,PRUNE2,VWC2,CACNB2,PTBP2,NUDT21,SYT6,BRSK2,GRIA1,GRIA2,INA,KCNK10,TNR,LILRA4,MAGI1,PDE3B,ZMYND8,DUSP26,CCSER2,ST8SIA5,FTO,MFSD4A,CRMP1,VCAN,PRKCZ,CTNND2,KIAA0408,WBP1L,LRRTM3,CA10,JAKMIP2,CNIH3,CSDE1,MED24,KCNA1,OLFM3,CDH20,PTPRD,CCDC3,KCNK1,KCNK2,PCDH15,DLG3,RAB5B,C12orf4,RET,EPB41L1" MicroRNA hsa-miR-145:mirSVR_lowEffct hsa-miR-145:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.21E-33 1.20E-29 2.43E-32 2.23E-31 101 1881 "DPF1,TTYH1,EPS8,SERPINA3,ACER3,MAP6,MBP,SYT9,MEG3,TMEM156,FCGR1A,FCGR1B,SCN3A,ASRGL1,ANK3,PPFIA1,ITSN1,CCDC80,SORBS1,ARHGAP5,CCDC88A,SLIT1,MTR,SORCS3,SMARCE1,RCOR3,KBTBD12,MEGF11,SCN3B,SOX1,CAB39,NMNAT2,KIF1B,GFAP,NEUROD1,GANAB,MLC1,GLS,ZNF638,MYRF,TBX15,NUDT21,EML4,VXN,NUMA1,GRIA2,LINC00839,CRB1,SPX,AIFM1,TLL2,NEURL1,KCNK10,DAAM2,HPS5,CDH8,LGI1,TPD52,PDE4B,ZMYND8,PFKFB3,NEGR1,FLRT1,SULT4A1,CABP1,CELF5,NXPH1,ACBD5,CNRIP1,CP,RNF14,PRKACB,DZIP3,PRKCZ,CTNND1,KIAA0513,ZNF385B,ITGAV,ELMO1,CSDE1,KCNA6,PTPRE,ARNT2,PCDH15,CAB39L,NKAIN1,KIF2A,DNAH9,RAB5B,SLC17A6,DPP6,ATN1,DSCAM,RASGRF1,SLC6A15,RFX5,JMJD1C,GPR61,FGFBP3,ARHGAP12,LRRC23" MicroRNA hsa-miR-1272:mirSVR_lowEffct hsa-miR-1272:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-33 1.30E-29 2.62E-32 2.41E-31 102 1919 "EPS8,PRR5L,ZFYVE27,ACTN2,ADGRV1,LDLRAD3,CSMD3,KLHL32,SORCS1,GRAMD1B,FOXRED2,TOMM40L,FGF14,SEMA6A,PPFIA1,PPM1E,DGKZ,ST3GAL3,JAKMIP3,LRRC55,SHANK2,DACH2,NAXD,SORCS3,RCOR3,ATP1A2,SCN3B,B3GALT2,SOX5,ARPP21,IDI2-AS1,CPLX2,FXYD6,C11orf87,BCL2L2,GPR162,RCOR2,NEUROD1,ARHGEF7,RHBDL3,PCDH11X,ZNF638,CAMSAP2,BTRC,KLHL4,TBX15,DDR1,ZEB1,NUDT21,VSTM2A,GRIA1,TMEM25,TGFBR3,GUCY1A1,PAH,DCLK1,PRMT8,PDYN,CASC2,CPT1C,ST8SIA5,FTO,VAV2,PMP2,PRRX1,NXPH1,MFSD4A,CRLS1,SNCAIP,RGS6,CHD5,RIMS4,SDC3,FMN2,KIAA0408,JAKMIP2,BLOC1S6,KCNA2,PTPRE,KCNC1,AK5,RABGAP1L,KCNK1,PEX5,DLG2,DLG3,CAB39L,NKAIN1,HS3ST4,WIPF2,KLRC2,PLEKHB2,PARP11,DPP6,SLC6A15,FAM135B,ATL1,SH3GLB1,RAVER2,C2orf80,EN2,RCAN2" MicroRNA hsa-miR-769-5p:mirSVR_lowEffct hsa-miR-769-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.55E-33 1.38E-29 2.79E-32 2.56E-31 88 1435 "ZFYVE27,ASIC1,EMID1,SYT9,MDM4,ADAR,KLHL32,TOMM40L,SEMA6A,ASIC4,PI16,SH3GL2,DOCK10,MAGI3,DGKZ,LRRC55,PKNOX2,SLC8A2,ASTN1,MYT1L,LHFPL4,IDI2-AS1,FXYD6,CLASP2,GPR162,NELL1,SEPT3,FAM168A,GLS,VAMP1,UNC5D,MMD2,ADGRL3,TBX15,PRUNE2,TCF12,HAP1,CECR2,VXN,NUCB1,BRSK2,PSD3,RFFL,GRIN1,OPCML,ARHGAP19,PCSK2,PDE1A,PDE2A,HMGB1,TMPRSS5,CASC2,NLGN3,CAMKV,SEMA5B,ANLN,UBTF,CCSER2,FADS2,BEST1,SF1,NCAN,PRKAB2,FMN2,CTNND1,PROX1,KIAA0408,MASP1,DPYSL5,PHYHIP,GON4L,CEP170,SMG7,TMCC2,CCDC3,DLG2,NKAIN1,DNM2,SLC17A6,DPP6,ATG16L1,ABI1,RASGRF1,ZNF248,RNF220,SFXN5,SH3GLB1,SEZ6" MicroRNA hsa-miR-2052:mirSVR_highEffct hsa-miR-2052:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-33 1.38E-29 2.79E-32 2.56E-31 92 1569 "ASIC1,MBP,RCSD1,CSMD2,ARID1A,F3,ADARB2,CLIP1,RTN1,ERMN,GPR158,BBOX1,HPCAL4,MOG,AMPH,ERICH3,ANK3,USP28,PPFIA1,ANXA7,SH3GL2,AQP4,ZNF365,MIER1,RUFY2,CADPS,SPHKAP,EIF4G3,PALLD,DKK3,SON,GAD2,ARPP21,EMC1,GART,NASP,SPART,NDUFA5,NEUROD1,GLS,PCDH11X,ZNF638,POPDC3,GNAS,UNC5D,VWC2,PTBP2,GRIA1,GRIK2,GPR88,ZFP91,TPM3,BEST3,MS4A7,SERPINE2,CADM1,NRXN1,CELF5,PACSIN1,POU3F2,PPP2R5C,KCNT2,MICAL2,PRKACB,USP54,ZBTB16,ANKS1B,LRRTM3,PTCH1,DNAJC6,PLPPR1,JAKMIP2,BDNF-AS,PRDM2,HP1BP3,LRP8,BLOC1S6,RABGAP1L,SNX27,TMEM255A,C12orf4,FAM13C,ZYG11B,NUP214,SEC61A2,SSPN,RPRD1A,VWA5A,ARHGAP12,SLC4A10,RCAN2,UEVLD" MicroRNA hsa-miR-183:mirSVR_lowEffct hsa-miR-183:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-33 1.60E-29 3.20E-32 2.94E-31 97 1745 "ACER3,MRVI1,LDLRAD3,CSMD2,PLEKHG5,KLHL32,GALNT13,CDC7,SCN3A,MOBP,USP28,ANXA7,PPM1E,DOCK10,ST3GAL3,SHTN1,ZNF365,ARFGAP2,CADPS,CGREF1,SPHKAP,LGI3,NAXD,SNCB,FYN,CAB39,NMNAT2,KIF1B,BCL2L2,PHLDB1,ARHGEF7,DCLK2,GNG4,GOLGB1,ANO4,PRUNE2,CACNA1E,LILRA1,HAP1,PTBP2,CECR2,NUMA1,GRIA1,GRIA4,CYB561A3,TMEM25,REPS2,HPS5,PADI2,PCDH8,PCDH9,LGI1,MAGI1,PRMT8,PIRT,ZMYND8,HMGB1,MS4A7,HERC2P3,CADM1,A2ML1,IFFO1,MFSD4A,MED1,SF1,CRLS1,NCAN,RBPJ,PRKAB2,FAM131B,NOS1AP,PLPPR5,PTCH1,ITGAV,BDNF-AS,PRDM2,COPS7A,RGMA,MAGI2,SV2A,KCNMA1,DNM2,SLC17A6,PLEKHB2,PARP11,RALGDS,JMJD1C,ARHGEF10L,SFXN5,SIDT2,PIANP,SH3GLB1,ABI2,VWA5A,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-3123:mirSVR_highEffct hsa-miR-3123:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.04E-33 1.65E-29 3.30E-32 3.03E-31 90 1505 "TTYH1,MDM4,GALNT13,SORCS1,LRRC7,ASIC4,FGR,UNC79,MOBP,PPM1E,SESN3,BCAN,TACC2,AQP4,ZNF365,MIER1,SLC6A9,ASPH,SORCS3,ATM,NAP1L2,NPAS3,NFASC,NCAM1,C11orf87,CLASP2,SMOC1,GNAS,CAMSAP2,UNC5D,PSRC1,ADGRL3,GOLGB1,GPM6B,PTBP2,VXN,SPX,USP2,INA,TMEM9,TJP1,TMEM257,MAEL,PCDH9,TPM4,MAGI1,PRMT8,LINC01102,ZMYND8,BEST3,CASC2,MS4A7,KIAA1549L,NRXN1,MEAF6,POU3F2,PPP2R5C,KCNT2,ATRNL1,PRKACB,RAB39A,PKN2,PLD5,NRSN1,ZNF385B,SYNC,LRRTM3,STMN4,BLOC1S6,KCNA1,OLFM3,KCNK2,PCDH15,NAV2,PEX5,DLG2,ABI1,FAM13C,DBX2,ABCC9,SLC6A15,JMJD1C,ZNF248,SH3GLB1,RERGL,FGFBP3,CBLN2,SLC4A10,EPB41L2,UEVLD" MicroRNA hsa-miR-610:mirSVR_lowEffct hsa-miR-610:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-33 1.66E-29 3.32E-32 3.04E-31 82 1245 "LOC100128239,ACER3,KLHL32,WAC,GRAMD1B,FOXRED2,LRRTM4,KIAA1109,FGF1,PLA2G6,LRRC7,FHL1,ELMOD1,ANK3,ITSN1,PPM1E,DOCK10,SORBS1,SYBU,NLGN1,RUFY2,PKNOX2,NAXD,ASPH,ATM,PHYHIPL,SOX5,ZCCHC24,ILDR2,ARPP21,KIF1B,CPLX2,NASP,NCAM1,COLGALT2,BCL2L2,NEUROD1,AJAP1,PCDH11X,SYT4,LUZP2,CAMSAP2,BTRC,TMEM136,PRUNE2,TCF7L2,ZEB1,PTBP2,LEFTY2,TNFRSF1B,C1orf94,PLEKHB1,CASC2,GDAP1L1,ZFYVE9,KIAA1549L,NOMO2,CCSER2,ST8SIA5,BEST1,NSD2,FAT3,SNCAIP,PPP3CB,MICAL2,RBPJ,IGSF1,PLPPR4,C1orf109,PTPRZ1,KCNJ11,PCDH15,CAB39L,DPP6,GNE,DBX2,CAMK1G,RGS7,SYT15,SSPN,CACNG7,FGFBP3" MicroRNA hsa-miR-181b-5p:TargetScan hsa-miR-181b-5p TargetScan 3.17E-33 1.72E-29 3.41E-32 3.13E-31 73 974 "ACER3,ASIC1,MAPT,NDRG2,ADARB2,CLIP1,ERMN,AMER2,CDC42BPA,ANK1,PPFIA1,ITSN1,DOCK10,GAS7,MADD,PKNOX2,CAPRIN2,ASTN1,ATM,ATP2B2,GAD2,NMNAT2,EMC1,SALL3,LMO3,CAMSAP2,ACSL6,PTBP2,NUDT21,CAMK2G,CECR2,PSD3,GRIA2,GRID1,GRIK2,GRIK3,GUCY1A2,KCNK10,CDH8,DCLK1,HMGB1,HNRNPK,KIAA1549L,NRXN1,NEGR1,NMT2,FTO,OSBPL3,ATRNL1,DOCK7,PKN2,CTNND1,MAPK8,PUM1,PROX1,RGMA,BLOC1S6,KCNA4,PTPRE,KCNH1,KCNJ10,ARNT2,KCNN3,DLG2,RAB3IL1,DPP6,ABI1,DTNA,L1CAM,LMO1,ELAVL4,EN2,EPB41" MicroRNA hsa-miR-181d-5p:TargetScan hsa-miR-181d-5p TargetScan 3.17E-33 1.72E-29 3.41E-32 3.13E-31 73 974 "ACER3,ASIC1,MAPT,NDRG2,ADARB2,CLIP1,ERMN,AMER2,CDC42BPA,ANK1,PPFIA1,ITSN1,DOCK10,GAS7,MADD,PKNOX2,CAPRIN2,ASTN1,ATM,ATP2B2,GAD2,NMNAT2,EMC1,SALL3,LMO3,CAMSAP2,ACSL6,PTBP2,NUDT21,CAMK2G,CECR2,PSD3,GRIA2,GRID1,GRIK2,GRIK3,GUCY1A2,KCNK10,CDH8,DCLK1,HMGB1,HNRNPK,KIAA1549L,NRXN1,NEGR1,NMT2,FTO,OSBPL3,ATRNL1,DOCK7,PKN2,CTNND1,MAPK8,PUM1,PROX1,RGMA,BLOC1S6,KCNA4,PTPRE,KCNH1,KCNJ10,ARNT2,KCNN3,DLG2,RAB3IL1,DPP6,ABI1,DTNA,L1CAM,LMO1,ELAVL4,EN2,EPB41" MicroRNA hsa-miR-181a-5p:TargetScan hsa-miR-181a-5p TargetScan 3.17E-33 1.72E-29 3.41E-32 3.13E-31 73 974 "ACER3,ASIC1,MAPT,NDRG2,ADARB2,CLIP1,ERMN,AMER2,CDC42BPA,ANK1,PPFIA1,ITSN1,DOCK10,GAS7,MADD,PKNOX2,CAPRIN2,ASTN1,ATM,ATP2B2,GAD2,NMNAT2,EMC1,SALL3,LMO3,CAMSAP2,ACSL6,PTBP2,NUDT21,CAMK2G,CECR2,PSD3,GRIA2,GRID1,GRIK2,GRIK3,GUCY1A2,KCNK10,CDH8,DCLK1,HMGB1,HNRNPK,KIAA1549L,NRXN1,NEGR1,NMT2,FTO,OSBPL3,ATRNL1,DOCK7,PKN2,CTNND1,MAPK8,PUM1,PROX1,RGMA,BLOC1S6,KCNA4,PTPRE,KCNH1,KCNJ10,ARNT2,KCNN3,DLG2,RAB3IL1,DPP6,ABI1,DTNA,L1CAM,LMO1,ELAVL4,EN2,EPB41" MicroRNA hsa-miR-181c-5p:TargetScan hsa-miR-181c-5p TargetScan 3.17E-33 1.72E-29 3.41E-32 3.13E-31 73 974 "ACER3,ASIC1,MAPT,NDRG2,ADARB2,CLIP1,ERMN,AMER2,CDC42BPA,ANK1,PPFIA1,ITSN1,DOCK10,GAS7,MADD,PKNOX2,CAPRIN2,ASTN1,ATM,ATP2B2,GAD2,NMNAT2,EMC1,SALL3,LMO3,CAMSAP2,ACSL6,PTBP2,NUDT21,CAMK2G,CECR2,PSD3,GRIA2,GRID1,GRIK2,GRIK3,GUCY1A2,KCNK10,CDH8,DCLK1,HMGB1,HNRNPK,KIAA1549L,NRXN1,NEGR1,NMT2,FTO,OSBPL3,ATRNL1,DOCK7,PKN2,CTNND1,MAPK8,PUM1,PROX1,RGMA,BLOC1S6,KCNA4,PTPRE,KCNH1,KCNJ10,ARNT2,KCNN3,DLG2,RAB3IL1,DPP6,ABI1,DTNA,L1CAM,LMO1,ELAVL4,EN2,EPB41" MicroRNA hsa-miR-4316:mirSVR_lowEffct hsa-miR-4316:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.78E-33 2.05E-29 4.06E-32 3.72E-31 86 1377 "ACER3,ASIC1,CDHR1,MBP,ATAT1,RTKN,CLIP1,ADCY2,ADD3,TUBB4A,TOMM40L,TESK2,SCN4B,LRRTM4,PLA2G6,LRRC7,ELMOD1,RPH3A,CGREF1,SPHKAP,DNAH17,CAPRIN2,SMARCE1,B3GAT1,ADGRA1,ATP1A2,NRG3,GABBR1,WDTC1,ZSWIM8,KIF1B,GART,RAP1GAP2,C11orf87,ERBIN,RND1,SEPT3,ARHGEF7,SYT4,GNAS,CAMTA1,CAMSAP2,ADGRL3,KLHL4,NUMA1,SHISA7,OPCML,CCKBR,TNFRSF1B,CDC42,TNS1,CDH10,ARHGAP19,PDE3B,TLX1,ANLN,PLXNB3,CABP1,BEST1,ACBD5,CNRIP1,MFSD4A,CHD1L,VCAN,DZIP3,KIAA1755,RAB39A,PRKCG,FAM131B,MASP1,SYTL2,PHYHIP,MED24,KCNA6,PTPRO,SRGAP3,SLC17A6,RALGDS,RASGRF1,NUP214,RGS7,ARHGEF10L,SSPN,PIANP,ABI2,EPB41L2" MicroRNA hsa-miR-664:PITA hsa-miR-664:PITA_TOP PITA 3.91E-33 2.12E-29 4.18E-32 3.84E-31 62 679 "LGR4,SYNDIG1,ARID1A,CSMD3,RTN1,ADD3,BCAR3,ELMOD1,HPCAL4,CDC42BPA,PKP4,NLGN1,AQP4,SLC1A2,PKNOX2,CCDC88A,CADPS,SNAP25,MEGF11,MYT1L,SOX5,CAB39,AHCYL1,SEPT3,NFIA,ACSL6,ZEB1,EML4,AKNA,GRIA2,GRIA4,KCNK10,CDC42,DCLK1,LGI1,CADM1,NEGR1,CCSER2,SLC25A27,FAT3,POU3F2,PNKD,TENM4,FMN2,PKN2,CTNND2,BRINP3,LRRTM3,CEP170,CSDE1,BLOC1S6,KCNA4,PTPRD,KCNK2,KCNMA1,SNX27,TMEM255A,PAK5,SIDT2,RBM12,EN2,RCAN2" MicroRNA hsa-miR-4324:mirSVR_lowEffct hsa-miR-4324:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.05E-33 2.19E-29 4.32E-32 3.96E-31 97 1752 "ACER3,MAP6,ERMN,LRRC7,CDC42BPA,RASA3,PPFIA1,PPM1E,NTNG1,MAGI3,DGKZ,BCAN,SORBS1,CACHD1,ZNF365,MSR1,SLC8A2,LGI3,NAXD,SORCS3,FYN,USP33,SOX1,ARPP21,ADAM15,NFASC,C11orf87,BCL2L2,ALDH1L1,SMOC1,ADHFE1,KAZN,CAMTA1,CNTN2,ADGRL3,TMEM136,PRUNE2,GPM6A,DIRAS1,PTBP2,NUDT21,CECR2,NUMA1,BRSK2,ADAMTS8,CYB561A3,GRM3,PTPN5,USP2,TMEM9,PCDH9,TPM3,PDE2A,PDE3B,BEST3,PLEKHB1,UBTF,CCSER2,OPALIN,SLC36A4,CRLS1,PTPA,PPP2R5C,PPP3CB,MICAL2,RBPJ,PRKAB2,DOCK7,RAB39A,PRKCZ,CTNND1,MAPK10,NOS1AP,MASP1,PLPPR1,COPS7A,KCNA1,SMG7,PTPRO,SV2A,KCNJ10,KCNMA1,RAB5B,KLRC2,DPP6,RALGDS,C12orf4,SUSD4,DTNA,ABCC9,SLC6A15,RET,ZNF248,PIANP,ABI2,EPB41,EPB41L1" MicroRNA hsa-miR-581:mirSVR_lowEffct hsa-miR-581:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.67E-33 2.53E-29 4.98E-32 4.57E-31 95 1685 "EPS8,PRR5L,ZFYVE27,TMEM74,MEG3,KCNIP2,RTN1,GRAMD1B,TOMM40L,HOGA1,TESK2,LRRC7,ANK3,SH3GL2,NTNG1,MAGI3,GPAM,SLITRK3,BCAS1,API5,LRRC55,ADGRA1,NRG3,WDTC1,IDI2-AS1,SPART,NCAM1,C11orf87,DCAF5,NEUROD1,ZNF638,DCLK2,DDHD2,ANO4,CACNA1A,WSCD1,GPM6B,VWC2,ZEB1,CLEC9A,TCF12,CECR2,GRIA2,GRIA4,GRID1,OPCML,ZDHHC22,KCNK10,MAEL,CDC42,PADI2,RBFOX2,TPM3,PDE1C,PRMT8,ZMYND8,ANO5,TLX1,SLC22A6,BEST1,ATCAY,NXPH1,MED1,PPP2R5C,SNCAIP,PPP3CB,RGS6,ATRNL1,SDC3,PLPP4,USP54,FAM131B,TOX,DPYSL5,SIRPA,CA10,PLPPR1,JAKMIP2,BDNF-AS,PTHLH,CNIH3,PRDM2,ZC3H11A,KCNA1,SRGAP3,PCDH15,PARP11,C12orf4,FAM13C,DTNA,FAM135B,TTLL7,SYT15,ELAVL4,BAALC" MicroRNA hsa-miR-875-5p:mirSVR_lowEffct hsa-miR-875-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-33 2.60E-29 5.10E-32 4.68E-31 82 1253 "RABEPK,CSMD2,KLHL32,SLC44A5,TESK2,LRRC7,BCAR3,FOXG1,MOG,SGIP1,CNIH2,PKP4,SH3GL2,APC,PAAF1,SLC1A7,MSR1,ARHGAP5,SLC8A3,DACH2,TMEM151A,NRG3,SCN3B,SON,KIF1B,DNER,NDUFA5,SMOC1,GFRA1,NELL1,NFIA,ARHGEF7,SYT4,LUZP2,GNG3,ANO4,CACNA1E,TCF12,EML4,CECR2,GRIA4,GRID1,TMEM257,ZFP91,MAEL,PCDH9,SEZ6L,MAGI1,JAM2,SERPINE2,NOMO2,NMT2,PACSIN1,MED1,CRLS1,VCAN,NCAN,DOCK7,PRKCZ,CTNND1,EDRF1,ZBTB16,ANKS1B,SPIRE1,PLPPR5,CADM2,ZC3H11A,KCNA1,SRGAP3,RABGAP1L,KCNJ11,CCDC3,KCNK2,NAV2,DLG2,KLRC2,FAM13C,DBX2,SLC6A15,RET,JMJD1C,INSYN2" MicroRNA hsa-miR-211:mirSVR_highEffct hsa-miR-211:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.28E-33 2.86E-29 5.60E-32 5.14E-31 92 1584 "DPF1,MAG,RABEPK,TTYH1,SDE2,LOC100128239,ZFYVE27,ARID1A,KLHL32,SLITRK1,RXRG,GALNT13,ADD3,WAC,CDC7,TMEM156,AMER2,SLC44A5,KIAA1109,SEMA6A,ELMOD1,SELL,ERICH3,ASRGL1,SGIP1,USP28,USP16,YPEL4,SLC8A3,NSG2,SORCS3,SMARCE1,RCOR3,B3GAT1,ATM,MYT1L,ZCCHC24,AHCYL1,ARPP21,NEK6,TTLL9,SMOC1,FGF17,RGL1,GANAB,ZNF638,CAMTA1,ATF7,CACNA1E,LRIT2,ZEB1,TCF12,SYT6,GRIA2,GRIA4,TIE1,ZFP91,CDC42,PCDH9,LGI1,TPM3,PDE4B,ZMYND8,BEST3,HMGB1,ANO5,OPALIN,SLC25A27,PRRX1,SLC36A4,POU3F2,RNF14,FEZ1,DZIP3,NRSN1,TOX,SIRPA,PRDM2,OLFM3,PTPRD,PTPRE,PLPPR4,C1orf109,RABGAP1L,KCNK2,PID1,TMEM255A,DNM2,DTNA,SEC61A2,ELAVL3,UEVLD" MicroRNA hsa-miR-22:mirSVR_lowEffct hsa-miR-22:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.31E-33 2.88E-29 5.63E-32 5.17E-31 94 1653 "ACLY,CNTNAP3,SYT9,MRVI1,CSMD2,ADCY2,SORCS1,ADORA1,CHST15,HOGA1,TESK2,SCN4B,MOBP,TRIM46,ANK2,FOLH1,PKP4,DOCK10,MAGI3,SORBS1,BCAS1,SHTN1,PAAF1,LRRC55,ARFGAP2,MT3,ASCL1,CGREF1,MEGF11,USP33,WDTC1,CAB39,ZSWIM8,NEUROD1,CASTOR3,DCLK2,SEMA4A,UNC5D,ANO4,TCF7L2,DIRAS1,AZIN2,EML4,CECR2,ZFP91,DAAM2,PAX6,TNFRSF1B,REPS2,PADI2,PCDH9,PTGDR2,TPM3,PDE2A,IGFN1,PRMT8,HMGB1,HNRNPK,JAM2,ZFYVE9,NEGR1,OPALIN,PRRX1,CRLS1,SNCAIP,RIMS4,NRSN1,MAPK10,PHYHIP,TOMM20,CADM2,PRTFDC1,COPS7A,STMN4,SMG7,PTPRE,KCNC1,SV2A,SRGAP3,RABGAP1L,TMCC2,KCNK1,KCNMA1,DNM2,DTNA,RET,RGS10,FAM135B,ARHGEF10L,PHC2,GPR61,VWA5A,BSCL2,EPB41" MicroRNA hsa-miR-152:mirSVR_lowEffct hsa-miR-152:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.43E-33 2.94E-29 5.74E-32 5.26E-31 98 1794 "ZFYVE27,ASIC1,ACHE,EMID1,MBP,SYT9,CSMD2,RTKN,MDM4,ADARB2,CLIP1,RTN1,ADCY2,PNMA8B,GRAMD1B,LRRC7,GOLGA7B,SELL,ERICH3,ANK2,RASA3,USP28,SLITRK3,TACC2,SYBU,SHTN1,SLC7A14,MSR1,PKNOX2,CCDC88A,CGREF1,CAPRIN2,ASTN1,RCOR3,SNAP25,EMC1,NCAM1,CLASP2,BCL2L2,ALDH1L1,ERBIN,INKA2,AJAP1,GLS,CAMTA1,TMEM136,CAMK2A,NUMA1,OPCML,TMEM25,USP2,P2RX7,ZDHHC22,CD81,RBFOX2,ARHGAP19,PDE2A,PDE3B,PDE4B,ZMYND8,TLX1,ZFYVE9,KIAA1549L,CCSER2,TJP2,FADS2,FTO,VAV2,PMP2,MED1,MASP1,DPYSL5,ELMO1,PRDM2,HP1BP3,RGMA,CEP170,PTPRE,KCNH1,KCNK1,SNX27,WIPF2,DNAH9,KLRC2,SLC17A6,PLEKHB2,PARP11,ATG16L1,ZNF248,SEC61A2,SLC39A12,VWA5A,SLC4A10,EPB41,EPB41L2,RASGRP2,UEVLD,BAALC" MicroRNA hsa-miR-135b:mirSVR_highEffct hsa-miR-135b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.26E-33 3.39E-29 6.61E-32 6.06E-31 85 1354 "ABAT,TMEM74,SYT9,EYA1,MRVI1,ATAT1,MDM4,ADAR,GALNT13,TMEM156,LRRC7,HPCAL4,MOBP,ANK3,ANXA7,PKP4,PPM1E,APC,NTNG1,ST3GAL3,API5,ZNF365,SLC6A9,CCDC88A,PDE8B,SPHKAP,ASPH,SMARCE1,ATP1A2,PALLD,ZCCHC24,CADM3,CPLX2,NAP1L2,STOX1,ZNF302,HEPN1,RGL1,ARHGEF7,POPDC3,GNG3,NODAL,CNTN2,TMEM136,KLHL4,ANO4,GPM6B,TCF7L2,PTBP2,CAMK2G,GRIA4,CRB1,TMEM9,HPS5,PCDH9,PDE3B,GDAP1L1,ANLN,OPALIN,DNAJC12,CNTN1,PRRX1,CRLS1,PPP2R5C,RGS6,MICAL2,ATRNL1,VCAN,FMN2,PKN2,USP54,CTNND1,NRSN1,MASP1,ZNF385B,ITGAV,JAKMIP2,CEP170,STMN4,KCNMA1,RTN4,PAK5,CAMK1G,RFX5,SLC4A10" MicroRNA hsa-miR-632:mirSVR_lowEffct hsa-miR-632:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.71E-33 3.63E-29 7.07E-32 6.49E-31 94 1658 "ZFYVE27,TMEM74,EXTL1,CSMD2,MDM4,PLEKHG5,DSCAML1,FOXRED2,FCGR1A,CHST15,DISP3,GOLGA7B,PPFIA1,NTNG1,AQP4,SLC1A2,MT3,SLC14A1,DACH2,SPHKAP,NAXD,ATP1A2,EIF4G3,SOX5,CADM3,SALL3,KIF1B,NCAM1,ALDH1L1,FGF17,ADHFE1,ARHGEF7,GNAS,MMD2,WWC1,ANO4,CACNA1A,TCF7L2,BRSK2,GRIA2,GRIA4,ADAMTS8,OLR1,OPCML,CRB1,MFSD2A,INA,TMEM9,PADI2,CDH8,CDH10,RBFOX2,PIRT,PLEKHB1,CASC2,NLGN3,KIAA1549L,NRXN2,CELF5,MFSD4A,CHD1L,PNKD,SF1,PPP2R5C,PPP3CB,NCAN,PRKAB2,PRKACB,DZIP3,PKN2,PRKCZ,BRINP3,TOX,BDNF-AS,BLOC1S6,PTPRD,KCNH1,SRGAP3,PCDH15,PEX5,KLRC3,SLC25A48,PARP11,FAM57B,GNE,PAK5,L1CAM,ABCC9,CAMK1G,RET,JMJD1C,SEC61A2,SEZ6,BAALC" MicroRNA hsa-miR-19b-2*:mirSVR_highEffct hsa-miR-19b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.09E-33 3.84E-29 7.46E-32 6.84E-31 84 1324 "ACER3,SYT9,RTN3,ARID1A,CSMD3,RTN1,SORCS1,TOMM40L,SEMA6A,MOG,ANK3,USP28,SH3GL2,NTNG1,GPAM,API5,SHTN1,RCOR3,EIF4G3,PHYHIPL,PALLD,B3GALT2,SOX5,CAB39,GAD2,NAP1L2,RGL1,ARHGEF7,ZNF638,CAMTA1,ADGRL3,ZEB1,PTBP2,CAMK2G,VSTM2A,GRIK2,CRB1,PTPN5,P2RX7,CDH8,TPM4,PDE1C,CHGA,CASC2,TUB,TMEFF2,JAM2,NLGN3,NRXN1,NEGR1,CCSER2,P2RY12,SLC36A4,NSD2,MFSD4A,CP,POU3F2,KCNT2,FEZ2,MICAL2,PLCH2,CTNND1,MAPK10,ANKS1B,SPIRE1,CA10,PRDM2,CEP170,CSDE1,MAGI2,PTPRD,AK5,KCNK2,KCNN3,TMEM255A,SLC17A6,ABI1,DTNA,RNF220,VWA5A,SLC4A10,ELAVL4,RPE65,TMEM100" MicroRNA hsa-miR-3139:mirSVR_lowEffct hsa-miR-3139:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.37E-33 3.99E-29 7.73E-32 7.09E-31 96 1730 "LDLRAD3,NDRG2,ADAR,ADCY2,SLITRK1,WAC,SORCS1,TUBB4A,GPR158,MOG,C1orf61,SOX6,SELL,ANK2,SH3GL2,NTNG1,SYBU,SLC1A7,URGCP,NSG2,TAGLN3,NAXD,BRINP2,ATM,SNCB,DKK3,GABBR1,MYH7,ARPP21,IDI2-AS1,ADAM15,NPAS3,NCAM1,CLASP2,ALDH1L1,KIRREL3,NEUROD1,SEPT3,CASTOR3,ZNF638,NHLH1,POPDC3,ROBO3,BTRC,PRUNE2,VXN,NUCB1,GRIA4,GPR88,PTGDR2,TPD52,MAGI1,PDE3B,PFKFB3,PLEKHB1,CASC2,HNRNPK,JAM2,GDAP1L1,KIAA1549L,UBTF,DNAJC12,ST8SIA5,BEST1,MFSD4A,PTPA,TENM4,MICAL2,ATRNL1,PRKAB2,DOCK7,SDC3,CMTM5,PLD5,ECE2,NOS1AP,MASP1,KIAA0513,PLPPR5,LRRTM3,HP1BP3,KCNK1,WIPF2,PLEKHB2,L1CAM,NUP214,RFX4,RFX5,FAM135B,PHC2,RNF220,SFXN5,CACNG7,PIANP,SH3GLB1,SEZ6" MicroRNA hsa-miR-363:mirSVR_highEffct hsa-miR-363:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.42E-33 4.02E-29 7.77E-32 7.13E-31 73 987 "RBM10,TMEM74,LGR4,CSMD2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,MOBP,ERICH3,ANK3,USP28,SESN3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,SON,B3GALT2,ARPP21,KIF1B,NPAS3,RGL1,AJAP1,PCDH11X,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,CAMK2A,GRIA1,RFFL,GRM3,OLR1,P2RX7,AIFM1,CDH10,TPM4,PDE1A,SCRG1,CADM1,CCSER2,CNRIP1,PPP3CB,KCNT2,ATRNL1,RBPJ,FMN2,RAB39A,EDRF1,ECE2,BRINP3,GON4L,ITGAV,CADM2,LRP8,PTPRD,PLPPR4,PTPRO,PTPRZ1,KCNK1,PEX5,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65" MicroRNA hsa-miR-875-3p:mirSVR_highEffct hsa-miR-875-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.14E-33 4.41E-29 8.51E-32 7.81E-31 99 1839 "ACER3,TMEM74,RCSD1,ACTN2,ADAR,CLIP1,KLRC4,SLITRK1,FABP7,SORCS1,ERMN,AMER2,NLGN4X,TOMM40L,GPR158,LRRC7,SEMA6A,ERICH3,SGIP1,ANK2,PKP4,PPM1E,APBA2,NTNG1,MAGI3,GPAM,NLGN1,BCAS1,PAAF1,ZNF365,MIER1,SLC2A5,RUFY2,LRRC55,SLC8A3,CCDC88A,NAXD,CAPRIN2,SORCS3,SNAP25,FYN,SOX5,CAB39,ARPP21,FXYD6,NCAM1,LMO3,C11orf87,CLASP2,ERBIN,INKA2,RGL1,NEUROD1,AJAP1,ARHGEF7,GLS,GNAS,BTRC,ADGRL3,GPM6B,GPR88,TGFBR3,IGSF21,PCSK2,PRMT8,ZMYND8,ANLN,A2ML1,P2RY12,NSD2,FAT3,NXPH1,CNRIP1,POU3F2,CRMP1,CRLS1,SNCAIP,PPP3CB,MICAL2,VCAN,CTNND2,PUM1,LRRTM3,DNAJC6,ELMO1,CEP170,PTPRD,C1orf109,RABGAP1L,KCNK2,PCDH15,DLG2,FAM66C,ABCC9,USH1C,SEC61A2,ABI2,RCAN2,RASGRP2" MicroRNA hsa-miR-1283:mirSVR_highEffct hsa-miR-1283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.53E-33 5.16E-29 9.94E-32 9.12E-31 101 1915 "SDE2,DUSP27,ADAR,KLRC4,WAC,CDC7,FABP7,SORCS1,ADORA3,SCN3A,KIAA1109,LRRC7,FGF14,BBOX1,UNC79,CDC42BPA,SESN3,SLITRK3,SHTN1,NSG2,ASPH,RCOR3,SNAP25,ATM,USP33,SON,SOX1,TNIK,GAD2,SALL3,TTLL9,NPAS3,SMOC1,VAMP1,ZNF638,UNC5D,MMD2,ADGRL3,KLHL4,GPM6B,TCF7L2,GRIK2,GRM3,OLR1,HPS5,PCDH8,CDH10,TPM3,GPR37L1,TMEFF2,CADM1,NRXN1,CAMKV,UBTF,FLRT1,SULT4A1,CNTN1,BTF3L4,NSD2,FAT3,SNCAIP,PPP3CB,KCNT2,FEZ2,RBPJ,FMN2,KIAA1755,PKN2,USP54,PUM1,BRINP3,TOX,GON4L,TOMM20,ZNF385B,PTCH1,DNAJC6,PTHLH,PRDM2,HP1BP3,MAGI2,OCIAD1,PLPPR4,PTPRZ1,NTM,RABGAP1L,KCNK1,KIF2A,ABI1,GNE,BSDC1,SLC6A15,ZYG11B,RFX4,JMJD1C,RGS10,PHC2,ZNF248,SLC39A12,SLC4A10,YY1AP1" MicroRNA hsa-miR-145:mirSVR_highEffct hsa-miR-145:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-32 5.52E-29 1.06E-31 9.74E-31 86 1396 "ADGRV1,RTKN,SLC25A25,CSMD3,CLIP1,ADD3,SORCS1,ERMN,KIAA1109,FGF14,SEMA6A,SGIP1,PKP4,NTNG1,GPAM,CACHD1,NLGN1,SHTN1,RUFY2,MSRA,SLC8A3,SLN,SNAP25,ATM,USP33,SON,ENKUR,ARPP21,IDI2-AS1,NCAM1,CLASP2,ZNF302,ERBIN,RGL1,PCDH11X,OS9,SYT4,LUZP2,CAMSAP2,PRUNE2,CACNB2,GRIA4,GRIK2,TF,TMEM25,TJP1,TPM3,TPM4,MAGI1,PDE3B,JAM2,ZFYVE9,TJP2,BEST1,BTF3L4,CHD1L,KCNT2,DOCK7,EDRF1,SIRPA,DNAJC6,BDNF-AS,PRDM2,MAGI2,BLOC1S6,ZC3H11A,KCNA4,KCNC1,KCNK1,KCNMA1,NAV2,SNX27,HS3ST4,TMEM255A,GOPC,DBX2,DTNA,PAK5,BSDC1,RFX4,RGS7,ATL1,EFNA3,VWA5A,SLC4A10,RPE65" MicroRNA hsa-miR-1274a:mirSVR_lowEffct hsa-miR-1274a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-32 5.74E-29 1.10E-31 1.01E-30 85 1364 "PAQR6,ADGRV1,CSMD3,WAC,AMER2,NLGN4X,CHST15,SCN3A,FGF1,PPFIA1,ITSN1,PKP4,SH3GL2,APC,NTNG1,DGKZ,GPAM,TACC2,SORBS1,SHTN1,ZNF365,LRRC55,SCG3,BRINP2,NRG3,SON,SOX1,MYT1L,SOX10,ZSWIM8,NMNAT2,NPAS3,SMOC1,ERBIN,PHLDB1,GLS,CNDP1,GPR26,BRSK2,AKNA,GRIA4,CRB1,LEFTY2,MFSD2A,ZDHHC22,CDK11B,PC,SEZ6L,LINC01102,FNDC5,BEST3,ASIC3,HNRNPK,CPT1C,C11orf49,BEST1,MFSD4A,POU3F2,MED1,SNCAIP,PPP3CB,FMN2,PRKCZ,ECE2,PROX1,RIMS3,PTCH1,DNAJC6,KCNA1,PTPRD,PTPRE,SV2A,SRGAP3,NTM,RABGAP1L,KCNJ10,KCNK1,PCDH15,BSDC1,ABCC9,ARHGEF10L,RPRD1A,SLC4A10,ELAVL4,RPE65" MicroRNA hsa-miR-558:mirSVR_lowEffct hsa-miR-558:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-32 6.43E-29 1.23E-31 1.13E-30 92 1601 "PLEKHG5,KLHL32,FCGR1A,AMPH,ANK2,PKP4,PPM1E,TACC2,SHTN1,AQP4,KIAA1614,SLIT1,ALDH4A1,ATM,CCDC181,ZSWIM8,NMNAT2,TTLL9,IDI2-AS1,DNER,NCAM1,GPR162,GFAP,NELL1,PHLDB1,NEUROD1,RND1,LRIT2,CACNB2,ZEB1,NRGN,AZIN2,CAMK2G,NUMA1,SPX,MFSD2A,INA,ZFP91,DAAM2,TNFRSF1B,TNS1,PCDH9,CDH8,RBFOX2,ZMYND8,FNDC5,HMGB1,TMPRSS5,NEGR1,OPALIN,ST8SIA5,PLXNB3,CNTN1,MEAF6,BEST1,MFSD4A,CRLS1,OSBPL3,RBPJ,PRKACB,KIAA1755,MAPK10,ZBTB16,KIAA0513,DPYSL5,GON4L,TOMM20,SYNC,PTHLH,PRDM2,STMN4,ZC3H11A,KCNA1,SV2A,SRGAP3,NTM,TMCC2,PCDH15,KCNMA1,NAV2,DLG2,DLG3,TMEM255A,DTNA,NUP214,RET,PHC2,GPR61,VWA5A,FGFBP3,BSCL2,RCAN2" MicroRNA hsa-miR-1267:mirSVR_lowEffct hsa-miR-1267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-32 6.88E-29 1.32E-31 1.21E-30 93 1637 "EPS8,SERPINA3,ABAT,MRVI1,ARID1A,CSMD3,GALNT13,WAC,ADORA3,TESK2,SCN3A,ZNF365,URGCP,LRRC55,SLC14A1,SCG3,SLCO1A2,NAXD,TMEM108,SNAP25,PHYHIPL,SOX5,SALL3,NFASC,RCOR2,RGL1,ADHFE1,NEUROD1,SEPT3,PCDH11X,LUZP2,ANO4,VWC2,CACNB2,LILRA1,TCF12,NUDT21,TMEM151B,GRID1,GRIK2,TMEM25,FBXL16,GUCY1A1,MAEL,PAX6,DCLK1,IGFN1,PFKFB3,TMEFF2,GDAP1L1,SEMA5B,PIK3CD,TJP2,CCDC136,PLXNB3,FAT3,PPP2R5C,MICAL2,ATRNL1,PRKAB2,CTNND1,NRSN1,WBP1L,SPIRE1,TOMM20,DNAJC6,CADM2,OCIAD1,PTPRD,KCNC1,PTPRZ1,KCNK2,PCDH15,OLIG1,SLC25A48,SLC17A6,DPP6,ATG16L1,GOPC,DTNA,PAK5,ZYG11B,CAMK1G,NUP214,FAM135B,ATL1,SEC61A2,SLC39A12,RAVER2,EPB41,RASGRP2,SEZ6,UEVLD" MicroRNA hsa-miR-1201:mirSVR_lowEffct hsa-miR-1201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-32 7.40E-29 1.41E-31 1.30E-30 77 1116 "GALNT13,AMER2,NLGN4X,LRRTM4,MOBP,USP28,ITSN1,APC,NTNG1,SORBS1,SHTN1,PAAF1,ZNF365,SLC1A6,SFMBT2,MSR1,YPEL4,NSG2,SLC14A1,SCMH1,CAPRIN2,TMEM108,IGSF9B,ENKUR,TTLL9,IDI2-AS1,ADAM15,NAP1L2,NPAS3,NFASC,GPR162,NEUROD1,LUZP2,DDHD2,CAMSAP2,TBX15,ACSL6,ZEB1,NUDT21,PCDHGA3,GRID1,GRIN1,CYB561A3,CRB1,GUCY1A2,NEURL1,CDH8,LGI1,MAGI1,LINC01102,TUB,TLX1,PIK3CD,COL9A2,POU3F2,KCNT2,ATRNL1,RAB39A,PUM1,FAM131B,NOS1AP,KIAA0408,BRINP3,RIMS3,BLOC1S6,SMG7,KCNJ9,CCDC3,KCNK2,PCDH15,SLC25A48,C12orf4,DBX2,BSDC1,NUP214,SLC4A10,EPB41L2" MicroRNA hsa-miR-374b*:mirSVR_lowEffct hsa-miR-374b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-32 7.74E-29 1.48E-31 1.35E-30 98 1816 "RABEPK,SDE2,PRR5L,CDHR1,TMEM74,SYNDIG1,ADGRV1,MDM4,NDRG2,RTN1,GALNT13,ADD3,GPR158,SCN3A,LRRC7,SLC30A10,HPCAL4,MOG,ERICH3,SGIP1,ANK3,PPFIA1,PPM1E,SESN3,GPAM,NLGN1,BCAS1,SHTN1,ARFGAP2,DACH2,RCOR3,TMEM108,ATM,CCDC181,ATP2B2,DKK3,B3GALT2,GAD2,ENKUR,ARPP21,ADAM15,DNER,NASP,NCAM1,ADHFE1,RHBDL3,NKX2-2,KAZN,NODAL,UNC5D,KLHL4,GPM6B,NPPA,TCF7L2,ZEB1,VSTM2A,BRSK2,GRIA1,GRIA4,RFFL,CRB1,AIFM1,TLL2,LGI1,ANO5,PFKFB3,CASC2,HERC2P3,ANLN,CELF5,PMS2,NXPH1,ACBD5,PPP3CB,FEZ2,FMN2,RAB39A,CTNND2,NOS1AP,KIAA0408,SYTL2,ANKS1B,GON4L,PSMD13,BDNF-AS,PTHLH,OLFM3,ARNT2,PCDH15,PEX5,DBX2,RTN4,SLC6A15,PHC2,TTLL7,RBM12,ARHGAP12,YY1AP1" MicroRNA hsa-miR-220b:mirSVR_lowEffct hsa-miR-220b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-32 8.09E-29 1.54E-31 1.41E-30 99 1853 "DPF1,SDE2,MAPT,SYT9,MRVI1,MDM4,ADORA1,TMEM156,HOGA1,FGF1,SEMA6A,ASIC4,MOBP,ANK3,ITSN1,APBA2,NLGN1,ZNF365,MIER1,SLC1A6,URGCP,SLC2A5,CCDC88A,NSG2,LGI3,DLL3,CAPRIN2,RCOR3,B3GAT1,IGSF9B,ATP2B2,GABBR1,SON,WDTC1,CADM3,GAD2,ZSWIM8,AHCYL1,IDI2-AS1,KIF1B,CPLX2,BCL2L2,NDUFA5,ERBIN,ADHFE1,NEUROD1,RND1,AJAP1,ZNF638,KAZN,UNC5D,FAM69C,ACSL6,CACNB2,ZEB1,NUDT21,PCDHGA3,CAMK2G,VXN,BRSK2,OPCML,CCKBR,ZDHHC22,DAAM2,CDC42,DCLK1,PRMT8,LRTM2,MS4A7,TLX1,HEPACAM,NMT2,ST8SIA5,MEAF6,BEST1,MFSD4A,SNCAIP,PPP3CB,RBPJ,DZIP3,SDC3,USP54,HES5,NOS1AP,FGFR1OP2,KIAA0513,LRRTM3,PLPPR4,C1orf109,SRGAP3,KCNJ9,ATG16L1,SLC25A41,PHC2,ZNF248,VANGL2,PIANP,TMEM100,EPB41L2" MicroRNA hsa-miR-603:mirSVR_highEffct hsa-miR-603:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-32 9.73E-29 1.85E-31 1.69E-30 86 1407 "LGR4,LDLRAD3,ADD3,LINC00461,FGR,SELL,AMPH,ANK2,ANXA7,PKP4,SH3GL2,CACHD1,NLGN1,BCAS1,AQP4,ZNF365,MADD,MSR1,ARHGAP5,NSG2,DACH2,ASTN1,SMARCE1,TMEM108,SNAP25,ATM,PALLD,USP33,DNER,SPART,NCAM1,ERBIN,GLS,ZNF638,CAMSAP2,TMEM136,LRIT2,CACNB2,ZEB1,NUDT21,VXN,SYT6,GRIA1,INA,MAEL,CDH10,PCSK2,MAGI1,ZNF384,NRXN1,ETNPPL,SF1,PTPA,PPP2R5C,FEZ2,FEZ1,RBPJ,FMN2,CTNND1,NRSN1,TOMM20,PLPPR5,ITGAV,PMEPA1,PTHLH,CADM2,HP1BP3,LRP8,MED24,KCNA2,PTPRD,NTM,KCNK1,PCDH15,PEX5,TMEM255A,PLEKHB2,PARP11,L1CAM,RET,INSYN2,ZNF248,SEC61A2,SLC39A12,RAVER2,EN2" MicroRNA hsa-miR-193b*:mirSVR_lowEffct hsa-miR-193b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-32 1.05E-28 1.99E-31 1.83E-30 98 1823 "TTYH1,ADARB2,ADCY2,WAC,SLC44A5,CHST15,ASIC4,ELMOD1,ANK2,USP28,ITSN1,BCAS1,SHTN1,AQP4,ARFGAP2,SLC8A3,DACH2,ASCL1,EIF4G3,SCN3B,SON,WDTC1,SOX1,GAD2,ZSWIM8,EMC1,C11orf87,CLASP2,BCL2L2,NDUFA5,INKA2,ADHFE1,ARHGEF7,GLS,GNAS,ROBO3,BTRC,KLHL4,ANO4,EML4,VXN,NUMA1,GRIA2,RFFL,CRB1,FBXL16,TIE1,AIFM1,MAEL,CDC42,ARHGAP19,LGI1,PDYN,HMGB1,TLX1,DUSP26,KIAA1549L,NRXN2,NMT2,SULT4A1,CNTN1,PMP2,MEAF6,SPATA6,PACSIN1,ATCAY,CRLS1,TENM4,PPP3CB,RGS6,MICAL2,CMTM5,USP54,NRSN1,MAPK10,ZBTB16,SYTL2,ANKS1B,GON4L,ZNF385B,ELMO1,PRDM2,COPS7A,ZC3H11A,PLPPR4,ARNT2,DLG3,HS3ST4,WIPF2,PID1,PLEKHB2,SLC25A18,ATN1,GNE,RFX4,SIDT2,ARHGAP12,ELAVL3" MicroRNA hsa-miR-483-3p:mirSVR_lowEffct hsa-miR-483-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-32 1.06E-28 2.01E-31 1.84E-30 90 1543 "LOC100128239,ACER3,MBP,RTN3,MRVI1,MDM4,ADCY2,TESK2,APBA2,APC,GPAM,AQP4,MIER1,MADD,PKNOX2,ARFGAP2,YPEL4,SLC8A3,CCDC88A,SLCO1A2,MTR,ALDH4A1,ATP1A2,MEGF11,DKK3,SCN3B,SON,ZSWIM8,KIF1B,NFASC,COLGALT2,ALDH1L1,DCAF5,GLS,GNAS,ROBO3,MYRF,MMD2,CACNA1E,CACNB2,PTBP2,NUDT21,NUMA1,LINC00839,ZFP91,TNS1,CDH8,ARHGAP19,MAGI1,BEST3,ANO5,CHGA,HEPACAM,CAMKV,HPR,PTPA,RGS6,MICAL2,PHACTR3,DZIP3,FMN2,CTNND1,NOS1AP,BRINP3,ZBTB16,CSDE1,BLOC1S6,OCIAD1,KCNK2,KCNMA1,NAV2,PEX5,HS3ST4,RAB5B,TMEM255A,FAM66C,FAM57B,DPP6,ATG16L1,DTNA,L1CAM,ABCC9,SLC6A15,FAM135B,ARHGEF10L,SEC61A2,SLC4A10,RCAN2,LRRC23,UEVLD" MicroRNA hsa-miR-150*:mirSVR_lowEffct hsa-miR-150*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-32 1.12E-28 2.12E-31 1.94E-30 87 1443 "SDE2,MEG3,CSMD2,KCNIP2,KLHL32,RTN1,SORCS1,DRAXIN,LRRC7,SLC30A10,MOBP,ANK2,USP28,DOCK10,DGKZ,GPAM,SYBU,API5,RPH3A,SLC2A5,BCO1,ARHGAP5,SLC8A3,SPHKAP,TMEM108,PALLD,USP33,AHCYL1,SPART,C11orf87,VAMP1,PCDH11X,MMD2,BTRC,ANO4,PRUNE2,LILRA1,ZEB1,NUDT21,NUMA1,GRIA4,OPCML,TGFBR3,TMEM9,PAH,CD81,TNFRSF1B,REPS2,ARHGAP19,PDE3B,ZMYND8,ADGRG1,ANO5,MS4A7,TMEFF2,CCSER2,PMP2,ACBD5,CNRIP1,MFSD4A,PTPA,RGS6,OSBPL3,PLCH2,PRKACB,PUM1,GON4L,MAGI2,KCNA1,PTPRD,PTPRE,C1orf109,SV2A,PCDH15,KCNMA1,NAV2,WIPF2,RAB5B,DNM2,SLC25A18,RAP1GAP,RASGRF1,DTNA,RGR,CBLN2,EPB41,BAALC" MicroRNA hsa-miR-3168:mirSVR_lowEffct hsa-miR-3168:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-32 1.23E-28 2.31E-31 2.12E-30 89 1512 "ACER3,ASIC1,TMEM74,LGR4,CEND1,SLITRK1,WAC,SORCS1,ERMN,HOGA1,SLC30A10,FOXG1,ANK2,PPFIA1,NTNG1,SORBS1,NLGN1,AQP4,RUFY2,MSR1,ARHGAP5,SHANK2,SPHKAP,CAPRIN2,DDX25,SMARCE1,SNAP25,ATM,CCDC181,CAB39,KIF1B,SPART,C11orf87,NDUFA5,ERBIN,NEUROD1,SEPT3,SLCO1C1,NFIA,ARHGEF7,ZNF638,KAZN,DDHD2,UNC5D,GPM6B,ACSL6,DDR1,PTBP2,TMEM151B,DDR2,GUCY1A2,PDE1C,CASC2,HNRNPK,NMT2,FTO,NSD2,CRLS1,PTPA,FEZ2,PRKAB2,USP54,MASP1,TOX,TOMM20,ZNF385B,PTCH1,PLPPR1,JAKMIP2,PTHLH,KCNA4,PTPRD,PTPRO,RABGAP1L,KCNJ11,KCNMA1,PEX5,KIF2A,OLIG1,ATG16L1,BSDC1,ABCC9,RGS7,RBM12,SH3GLB1,LMO1,RAVER2,OLIG2,RCAN2" MicroRNA hsa-miR-526b:mirSVR_highEffct hsa-miR-526b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-32 1.31E-28 2.46E-31 2.26E-30 74 1035 "EPS8,SDE2,ACLY,ACTN2,FAM43B,ATAT1,CSMD2,CLIP1,ADORA3,CHST15,TOMM40L,PDZD4,FOXM1,ERICH3,ANK2,USP28,SH3GL2,NLGN1,ZNF365,PDE8B,SCG3,SMARCE1,TNIK,IDI2-AS1,DNER,CLASP2,POPDC3,DCLK2,KAZN,CAMSAP2,PRUNE2,GPM6A,ACSL6,CECR2,VXN,GRIA4,USP2,ZFP91,PAH,MAEL,PAX6,DCLK1,LGI1,TPM4,ANO5,HEPACAM,ZFYVE9,PMP2,SPATA6,NXPH1,ACBD5,RNF14,PHACTR3,DOCK7,CTNND1,FGFR1OP2,SYNC,PLPPR1,PRTFDC1,LRP8,PTPRE,PTPRO,KCNJ11,KCNK1,KLRC3,GOPC,RASGRF1,ABCC9,SLC6A15,SEC61A2,RPRD1A,ARHGAP12,CBLN2,EPB41" MicroRNA hsa-miR-487a:mirSVR_lowEffct hsa-miR-487a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-32 1.32E-28 2.47E-31 2.27E-30 93 1651 "RPL38,TMEM74,ARID1A,MDM4,WAC,BCAR3,ELMOD1,ANK3,CNIH2,APC,GPAM,CACHD1,ST3GAL3,API5,SHTN1,AQP4,ZNF365,RUFY2,CADPS,SLCO1A2,LGI3,ASPH,SMARCE1,TMEM108,USP33,KIF1B,CPLX2,DNER,SPART,RGL1,PCDH11X,LUZP2,KAZN,NODAL,CNTN2,TMEM136,TBX15,PRUNE2,ADAMTS8,MAEL,CDC42,TPD52,PCSK2,ZMYND8,CHGA,HNRNPK,CADM1,P2RY12,NXPH1,ACBD5,MFSD4A,ETNPPL,PTPA,PRKAB2,DOCK7,PKN2,PLD5,CTNND2,PUM1,PROX1,KIAA0408,WBP1L,SYTL2,SPIRE1,ZNF385B,PTCH1,CADM2,CNIH3,PRTFDC1,CEP170,STMN4,KCNA2,RABGAP1L,PEX5,DLG2,RAB5B,TMEM255A,SLC17A6,FAM66C,PARP11,DSCAM,PAK5,SLC6A15,RFX4,RGS7,ATL1,SYT15,RPRD1A,GPR61,ABI2,SLC4A10,EPB41L2,LRRC23" MicroRNA hsa-miR-16-1*:mirSVR_highEffct hsa-miR-16-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.70E-32 1.46E-28 2.74E-31 2.51E-30 96 1759 "ACER3,MBP,MDM4,F3,CLIP1,SLITRK1,SLC44A5,LINC00461,KIAA1109,FHL1,ERICH3,ANK2,RASA3,SESN3,NTNG1,MAGI3,BCAS1,API5,SHTN1,MIER1,CADPS,ASCL1,SPHKAP,SMARCE1,RCOR3,ATM,USP33,SOX5,CAB39,ILDR2,ARPP21,GART,NPAS3,SPART,NCAM1,RGL1,SLCO1C1,ZNF638,LUZP2,GNAS,CAMTA1,CAMSAP2,MYRF,GPM6B,LRIT2,CACNB2,ZEB1,TCF12,NUDT21,EML4,GRIA4,GRM3,LEFTY2,TMEM257,ZDHHC22,PAH,REPS2,DCLK1,ZNF384,BEST3,ANO5,PLEKHB1,JAM2,TJP2,POU3F2,CRLS1,PPP3CB,ATRNL1,FMN2,IGSF1,BRINP3,DPYSL5,ANKS1B,SPIRE1,LRRTM3,DNAJC6,ITGAV,PTHLH,HP1BP3,CEP170,KCNA4,C1orf109,PTPRZ1,DPP6,ABI1,DSCAM,DBX2,DTNA,PAK5,RET,RFX4,ZNF248,RPRD1A,ARHGAP12,CBLN2,SLC4A10" MicroRNA hsa-miR-1244:mirSVR_highEffct hsa-miR-1244:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.85E-32 1.54E-28 2.88E-31 2.64E-30 85 1383 "MAP6,LGR4,RCSD1,EYA1,ARID1A,CSMD3,KLRC4,GALNT13,SORCS1,FCGR1A,FCGR1B,FGF1,BCAR3,MOBP,MOG,FOXM1,SGIP1,ANK2,CNIH2,APC,NTNG1,USP16,SLC1A6,CCDC88A,ASPH,ATM,PHYHIPL,MEGF11,USP33,B3GALT2,TNIK,CADM3,ENKUR,EMC1,CLASP2,ERBIN,GLS,PCDH11X,KLHL4,GPM6A,PRLHR,NUDT21,GRIA4,SPX,MAEL,CDC42,MAGI1,HMGB1,MS4A7,SERPINE2,NRXN1,CCSER2,CNTN1,CELF5,NSD2,CRLS1,PPP3CB,KCNT2,MICAL2,PRKAB2,FMN2,RAB39A,USP54,MAPK8,PUM1,FGFR1OP2,TOX,WBP1L,SYTL2,GON4L,PSMD13,PTPRZ1,NTM,RABGAP1L,KCNJ10,PCDH15,KCNN3,TMEM255A,RAD52,ABI1,SLC6A15,RET,ZNF248,SYT15,SH3GLB1" MicroRNA hsa-miR-9*:mirSVR_highEffct hsa-miR-9*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-32 1.59E-28 2.96E-31 2.71E-30 93 1655 "EPS8,ACER3,WLS,CLIP1,KLHL32,RTN1,SORCS1,ERMN,AMER2,GPR158,FGF14,FHL1,PKP4,APBA2,JAKMIP3,ZNF365,MIER1,ARHGAP5,SHANK2,DACH2,ASPH,SORCS3,SMARCE1,SON,SOX1,AHCYL1,EMC1,TTLL9,DNER,NAP1L2,LMO3,C11orf87,CLASP2,DCAF5,PHLDB1,SEPT3,GLS,DDHD2,GPM6B,GPR17,GPR19,TCF12,EML4,SYT6,GRIA2,OLR1,USP2,TLL2,REPS2,TPD52,TPM3,TPM4,MAGI1,PDE3B,ACOT7,HMGB1,ANO5,CASC2,NRXN1,TJP2,MEAF6,SPATA6,POU3F2,MED1,MICAL2,OSBPL3,RBPJ,DOCK7,FMN2,PKN2,PRKCZ,PUM1,SIRPA,ITGAV,PLPPR1,CADM2,HP1BP3,CSDE1,ZC3H11A,OLFM3,OCIAD1,PID1,TMEM255A,PARP11,DTNA,PAK5,ABCC9,RGS10,FAM135B,RLBP1,SEC61A2,RPRD1A,CBLN2" MicroRNA hsa-miR-3164:mirSVR_lowEffct hsa-miR-3164:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-32 1.65E-28 3.06E-31 2.81E-30 92 1621 "SERPINA3,ACER3,TMEM74,MBP,SYT9,ACTN2,CSMD2,WLS,CLIP1,RXRG,ADD3,PNMA8B,ERMN,NLGN4X,CHST15,HOGA1,BBOX1,FOXG1,PDZD4,ERICH3,ITSN1,CCDC80,JAKMIP3,BCO1,SLN,SMARCE1,ATM,KIF21B,ILDR2,KIF1B,CLASP2,NDUFA5,SMOC1,NEUROD1,FAM168A,NFIA,PCDH11X,SYT4,DDHD2,NODAL,MYRF,PRUNE2,GPM6A,TCF7L2,NRDC,GRIA2,GRID1,GRM3,LINC00839,P2RX7,TLL2,PAH,REPS2,ARHGAP19,PCSK2,PDE1A,IGFN1,CADM1,CCSER2,OPALIN,FTO,IFFO1,KCNT2,NCAN,DOCK7,DZIP3,IGSF1,TOX,SYTL2,GON4L,SPIRE1,PLPPR5,ITGAV,MAGI2,STMN4,KCNA1,PTPRE,AK5,KCNK2,WIPF2,FAM66C,ATN1,GOPC,RET,VANGL2,SFXN5,SSPN,CBLN2,SLC4A10,TMEM100,EPB41L1,BAALC" MicroRNA hsa-miR-3166:mirSVR_lowEffct hsa-miR-3166:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-32 1.68E-28 3.12E-31 2.86E-30 99 1870 "EPS8,ASIC1,RBM10,SYT9,RTN3,ATAT1,F3,GRAMD1B,FOXRED2,GPR158,SEMA6A,SEMA6C,PPM1E,GAS7,NLGN1,PAAF1,MADD,RUFY2,LRRC55,ARFGAP2,NSG2,MTR,RCOR3,KBTBD12,SNAP25,TMEM151A,SNCB,NRG3,WDTC1,GAD2,ADAM15,ALDH1L1,SEPT3,KAZN,MYRF,CDK5R2,ADGRL3,GOLGB1,FAM69C,LILRA1,AZIN2,PTBP2,CAMK2A,CECR2,VSTM2A,BRSK2,RFFL,CYB561A3,LINC00839,PTPN5,MFSD2A,FBXL16,TLL2,DCLK1,LILRA4,FNDC5,JAM2,KIAA1549L,CCSER2,OPALIN,ST8SIA5,FLRT1,FTO,CELF5,IFFO1,NXPH1,CNRIP1,MFSD4A,PNKD,SF1,CRLS1,PPP3CB,NCAN,PRKAB2,PKN2,PLD5,CTNND1,NRSN1,ECE2,TOX,WBP1L,DPYSL5,ZNF385B,ITGAV,CADM2,PTPRE,AK5,RABGAP1L,KCNK2,DLG2,NKAIN1,HS3ST4,SLC17A6,RAP1GAP,NUP214,RET,EEF1A2,RERGL,RPE65" MicroRNA hsa-miR-1271-5p:TargetScan hsa-miR-1271-5p TargetScan 3.17E-32 1.72E-28 3.18E-31 2.92E-30 68 866 "ABAT,RIMKLA,ADD3,FOXRED2,SCN3A,LRRC7,FGF14,FHL1,CDC42BPA,MAGI3,RPH3A,CCDC88A,NSG2,PDE8B,BRINP2,ASTN1,FYN,PHYHIPL,B3GALT2,GAD2,AHCYL1,B4GALNT1,NPAS3,RAP1GAP2,CLASP2,GFRA1,PHLDB1,AJAP1,FAM168A,CAMSAP2,CDK5R2,GPM6A,GPM6B,GRIA1,GRID1,GRIK4,INA,KCNK10,PAX6,REPS2,PC,PCDH8,LGI1,MAGI1,CADM1,PRRX1,FAT3,MED1,RIMS4,PKN2,CTNND1,KIAA0513,RIMS3,PMEPA1,CADM2,ELMO1,CEP170,CDH20,KCNN3,ATG16L1,DSCAM,GNE,L1CAM,BSDC1,JMJD1C,ABI2,RAVER2,ELAVL4" MicroRNA hsa-miR-96-5p:TargetScan hsa-miR-96-5p TargetScan 3.17E-32 1.72E-28 3.18E-31 2.92E-30 68 866 "ABAT,RIMKLA,ADD3,FOXRED2,SCN3A,LRRC7,FGF14,FHL1,CDC42BPA,MAGI3,RPH3A,CCDC88A,NSG2,PDE8B,BRINP2,ASTN1,FYN,PHYHIPL,B3GALT2,GAD2,AHCYL1,B4GALNT1,NPAS3,RAP1GAP2,CLASP2,GFRA1,PHLDB1,AJAP1,FAM168A,CAMSAP2,CDK5R2,GPM6A,GPM6B,GRIA1,GRID1,GRIK4,INA,KCNK10,PAX6,REPS2,PC,PCDH8,LGI1,MAGI1,CADM1,PRRX1,FAT3,MED1,RIMS4,PKN2,CTNND1,KIAA0513,RIMS3,PMEPA1,CADM2,ELMO1,CEP170,CDH20,KCNN3,ATG16L1,DSCAM,GNE,L1CAM,BSDC1,JMJD1C,ABI2,RAVER2,ELAVL4" MicroRNA hsa-miR-488*:mirSVR_lowEffct hsa-miR-488*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.33E-32 1.80E-28 3.33E-31 3.05E-30 90 1554 "RABEPK,EPS8,RTKN,ADD3,TUBB4A,FCGR1A,MOBP,ANK3,CNIH2,APC,GPAM,NLGN1,ZNF365,BCO1,PKNOX2,CCDC88A,CADPS,NAXD,ASPH,SMARCE1,ATM,MEGF11,MYBPC1,B3GALT2,GAD2,ENKUR,B4GALNT1,NEK6,TTLL9,NFASC,COLGALT2,STOX1,ARHGEF7,PCDH11X,SYT4,LUZP2,DCLK2,KAZN,TBX15,GPM6B,LILRA1,TCF7L2,GRIA4,OMG,TGFBR3,FBXL16,ATG4C,REPS2,LGI1,CA14,ANO5,CASC2,TUB,HNRNPK,JAM2,CADM1,A2ML1,CCSER2,CNTN1,SPATA6,FAT3,POU3F2,RNF14,PTPA,PPP2R5C,SNCAIP,ATRNL1,VCAN,BRINP3,ZNF385B,PTHLH,CNIH3,CSDE1,PTPRE,KCNH1,KCNMA1,KIF2A,SLC17A6,RALGDS,ZYG11B,RFX4,JMJD1C,ARHGEF10L,SYT15,RBM12,RPRD1A,RAVER2,EN2,OLIG2,SEZ6" MicroRNA hsa-miR-592:mirSVR_lowEffct hsa-miR-592:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-32 1.89E-28 3.49E-31 3.20E-30 92 1624 "MAP6,MBP,ADCY2,GALNT13,SEMA6A,FHL1,MOBP,SOX6,ASRGL1,CCDC80,DGKD,TACC2,SLC1A7,LRRC55,ARHGAP5,NSG2,DNAH17,SLIT1,ASPH,MTR,KBTBD12,GABBR1,KIF21B,NMNAT2,CPLX2,NCAM1,CLASP2,BCL2L2,NFIA,CASTOR3,PCDH11X,ZNF638,CAMSAP2,CNDP1,LRIT2,CACNB2,ZEB1,DIRAS1,PCDHGA3,CECR2,VXN,GRIA4,LINC00839,CRB1,ZDHHC22,TPD52,FNDC5,PLEKHB1,TMEFF2,TLX1,NEGR1,CPT1C,C11orf49,BEST1,FAT3,MFSD4A,POU3F2,SNCAIP,OSBPL3,ATRNL1,RBPJ,PRKCZ,MAPK10,PROX1,KIAA0408,BRINP3,WBP1L,BDNF-AS,PRDM2,HP1BP3,CSDE1,MAGI2,KCNA6,NTM,SNX27,DLG2,HS3ST4,PID1,KLRC3,DNM2,DTNA,JMJD1C,FAM135B,ZNF248,SH3GLB1,RPRD1A,ABI2,VWA5A,RAVER2,EN2,RCAN2,BAALC" MicroRNA hsa-miR-3118:mirSVR_lowEffct hsa-miR-3118:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.66E-32 1.98E-28 3.65E-31 3.35E-30 92 1625 "SDE2,ACER3,ASIC1,KLHL32,RXRG,AMER2,FOXRED2,HOGA1,LRRTM4,FGF1,LRRC7,BBOX1,MOG,FOXM1,CNIH2,PPM1E,DGKZ,GPAM,BCAS1,CCDC88A,SLIT1,KBTBD12,ATM,PALLD,DKK3,WDTC1,SOX5,ENKUR,TTLL9,ADAM15,NCAM1,NDUFA5,STOX1,NEUROD1,FAM168A,CAMTA1,GNG4,ADGRL3,NUDT21,GRIA1,GRIA2,OPCML,INA,TMEM257,KCNK10,MAEL,PADI2,CDH8,PCSK2,PDE4B,ACOT7,TMPRSS5,HPSE2,ANO5,KIAA1549L,NEGR1,ANLN,UBTF,FTO,CCDC136,PMP2,CHD1L,CSF3R,ATRNL1,VCAN,NCAN,SDC3,PLD5,ARHGEF4,HES5,KIAA0408,BRINP3,SYTL2,DNAJC6,CADM2,ELMO1,MAGI2,BLOC1S6,KCNA4,KCNA6,DLG2,NKAIN1,PID1,SLC25A48,FAM66C,RASGRF1,DTNA,JMJD1C,RGS7,INSYN2,ARHGAP12,ELAVL3" MicroRNA hsa-miR-3172:mirSVR_lowEffct hsa-miR-3172:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.82E-32 2.61E-28 4.80E-31 4.40E-30 97 1808 "TTYH1,ADARB2,WAC,SLC44A5,CHST15,ASIC4,ELMOD1,ANK2,USP28,ITSN1,BCAS1,SHTN1,AQP4,ARFGAP2,SLC8A3,DACH2,ASCL1,EIF4G3,SCN3B,SON,WDTC1,SOX1,GAD2,ZSWIM8,EMC1,C11orf87,CLASP2,BCL2L2,NDUFA5,INKA2,ADHFE1,PHLDB1,ARHGEF7,GLS,GNAS,ROBO3,BTRC,KLHL4,ANO4,EML4,VXN,NUMA1,GRIA2,RFFL,CRB1,FBXL16,TIE1,AIFM1,MAEL,CDC42,ARHGAP19,LGI1,PDYN,HMGB1,TLX1,DUSP26,KIAA1549L,NRXN2,NMT2,SULT4A1,PMP2,MEAF6,SPATA6,PACSIN1,ATCAY,CRLS1,TENM4,PPP3CB,RGS6,MICAL2,CMTM5,USP54,NRSN1,ZBTB16,SYTL2,ANKS1B,GON4L,ZNF385B,ELMO1,PRDM2,COPS7A,ZC3H11A,PLPPR4,ARNT2,DLG3,HS3ST4,WIPF2,PID1,PLEKHB2,SLC25A18,ATN1,GNE,RFX4,SIDT2,ARHGAP12,ELAVL3,EN2" MicroRNA hsa-miR-584:mirSVR_lowEffct hsa-miR-584:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.09E-32 2.76E-28 5.06E-31 4.64E-30 87 1461 "EPS8,ABAT,PRR5L,ADGRV1,RTKN,CSMD3,ADD3,WAC,GRAMD1B,TESK2,FGF1,BBOX1,UNC79,ELMOD1,SOX6,GPAM,NLGN1,JAKMIP3,DACH2,CSPG5,SLIT1,ASPH,BRINP2,TMEM108,ATM,USP33,NAP1L2,LMO3,NDUFA5,NEUROD1,ZNF638,LUZP2,DDHD2,CAMTA1,CACNB2,TCF12,PTBP2,VXN,AKNA,GRIA4,GRM3,OPCML,MFSD2A,TMEM257,ZDHHC22,CDC42,ARHGAP19,TPM3,MAGI1,ZNF384,PRMT8,TLX1,HEPACAM,NRXN1,NEGR1,SF1,SNCAIP,FEZ2,FEZ1,ATRNL1,RBPJ,DOCK7,DZIP3,SDC3,PKN2,PLD5,ECE2,ITGAV,PMEPA1,BDNF-AS,CADM2,HP1BP3,COPS7A,CEP170,CSDE1,BLOC1S6,SMG7,PTPRE,RABGAP1L,CAB39L,ABI1,GOPC,ZYG11B,FAM135B,TTLL7,SYT15,ELAVL4" MicroRNA hsa-miR-520g:mirSVR_highEffct hsa-miR-520g:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.27E-32 2.85E-28 5.23E-31 4.79E-30 85 1395 "ZFYVE27,ACER3,MAP6,EYA1,ATAT1,CSMD3,F3,KLHL32,RTN1,WAC,NLGN4X,HOGA1,FOXG1,ERICH3,APC,MAGI3,NLGN1,ZNF365,SORCS3,EIF4G3,ADGRB2,NPAS3,NCAM1,C11orf87,CLASP2,GLS,ZNF638,DCLK2,DDHD2,CAMSAP2,GOLGB1,GPM6B,TCF12,GPR88,OLR1,PTPN5,ZFP91,PAH,MAEL,HPS5,PCDH8,ARHGAP19,TPM3,TPM4,MAGI1,ZNF384,PRMT8,HERC2P3,TLX1,ANLN,OPALIN,C11orf49,ACBD5,PPP3CB,OSBPL3,PKN2,IGSF1,CTNND2,TOX,WBP1L,LRRTM3,ITGAV,CA10,PLPPR1,PTHLH,OLFM3,KCNC1,PTPRO,PCDH15,DLG2,RAB5B,DBX2,RTN4,ABCC9,SLC6A15,ZYG11B,RFX4,JMJD1C,RGS7,FAM135B,ATL1,SEC61A2,SLC4A10,TMEM100,EPB41L2" MicroRNA hsa-miR-3176:mirSVR_lowEffct hsa-miR-3176:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.49E-32 2.97E-28 5.44E-31 4.99E-30 97 1811 "SDE2,LOC100128239,MAP6,LGR4,FAM43B,PNMA8B,GRAMD1B,TMEM156,DRAXIN,TOMM40L,AGT,MOG,ITSN1,APBB1,MAGI3,ST3GAL3,ZNF365,MIER1,MSRA,LRRC55,CCDC88A,B3GAT1,ALDH4A1,TMEM151A,FYN,PALLD,GABBR1,USP33,TNIK,ZSWIM8,B4GALNT1,TTLL9,ADAM15,GART,FXYD6,NCAM1,COLGALT2,BCL2L2,ALDH1L1,PHLDB1,SEPT3,ARHGEF7,RHBDL3,GNAS,MMD2,CNTN2,TMEM136,TBX15,DDR1,CACNB2,NUDT21,CAMK2G,AKNA,GRIA2,GRIA4,GRID1,TMEM9,TNFRSF1B,HPS5,PADI2,PCSK2,PRMT8,ZMYND8,BEST3,SEMA5B,PIK3CD,CPT1C,C11orf49,BEST1,SLC36A4,NSD2,NXPH1,MED1,SNCAIP,PRKAB2,CMTM5,PRKCZ,USP54,CTNND1,NRSN1,GON4L,ZNF385B,ELMO1,COPS7A,PTPRE,KCNH1,SRGAP3,KCNMA1,PLEKHB2,FAM57B,RAP1GAP,CRTAC1,ZYG11B,ZNF248,SFXN5,RBM12,EPB41" MicroRNA hsa-miR-758:mirSVR_lowEffct hsa-miR-758:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.90E-32 3.20E-28 5.83E-31 5.35E-30 87 1464 "ZFYVE27,SYT9,CLIP1,KLRC4,GPR158,KIAA1109,LRRC7,FHL1,ERICH3,ANK2,MAGI3,DGKZ,SORBS1,LRRC4C,MSR1,SLCO1A2,SPHKAP,MTR,TMEM108,EIF4G3,SON,SOX1,MYT1L,B3GALT2,SALL3,KIF1B,NAP1L2,NPAS3,RAP1GAP2,SPART,SEPT3,FAM168A,ACSBG1,GLS,PCDH11X,CAMTA1,WWC1,ACSL6,ZEB1,GRIA2,GRIK3,OLR1,OPCML,INA,ATG4C,DAAM2,REPS2,PCDH9,HRH3,TPM3,PDE4B,LINC01102,CASC2,GDAP1L1,CADM1,KIAA1549L,CNTN1,P2RY12,POU3F2,TENM4,PPP3CB,MICAL2,ATRNL1,NCAN,RBPJ,PRKACB,PKN2,PLD5,FAM131B,KIAA0408,CA10,CADM2,PRDM2,MAGI2,RABGAP1L,DLG2,DNM2,RAD52,RASGRF1,FAM13C,RTN4,PAK5,RGS7,INSYN2,ATL1,RPRD1A,ABI2" MicroRNA hsa-miR-1255b:mirSVR_lowEffct hsa-miR-1255b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.67E-32 3.61E-28 6.58E-31 6.03E-30 92 1638 "ABAT,ASIC1,MAPT,CDHR1,SYT9,RCSD1,ACTN2,ADGRV1,ATAT1,LDLRAD3,KCNIP2,KLRC4,CDC7,GRAMD1B,TOMM40L,LRRC7,FGR,SOX6,USP28,PKP4,DGKZ,LRRC55,DLL3,NAXD,MTR,SORCS3,SNAP25,WDTC1,B3GALT2,ZCCHC24,SOX10,ENKUR,TTLL9,KIF1B,FXYD6,RAP1GAP2,C11orf87,STOX1,GPR162,GFAP,NEUROD1,ARHGEF7,GNG3,GPM6A,CACNA1E,ZEB1,HAP1,NUDT21,CRB1,ZFP91,DAAM2,PCDH9,HMGB1,TLX1,JAM2,HEPACAM,SEMA5B,CPT1C,OPALIN,TJP2,VAV2,BEST1,BTF3L4,IFFO1,NSD2,CHD1L,PTPA,PPP2R5C,PRKACB,CMTM5,PRKCZ,USP54,NRSN1,FAM131B,MASP1,LRP8,OCIAD1,PTPRD,KCNJ11,KCNK1,PCDH15,PEX5,RALGDS,C12orf4,FAM13C,ABCC9,INSYN2,ARHGEF10L,SYT15,RPRD1A,OLIG2,EPB41L1" MicroRNA hsa-miR-498:mirSVR_highEffct hsa-miR-498:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.68E-32 3.62E-28 6.58E-31 6.03E-30 72 992 "RTN3,EYA1,ADAR,SORCS1,LRRTM4,KIAA1109,FGF1,LRRC7,ELMOD1,SLC30A10,MOBP,ITSN1,PKP4,NLGN1,ST3GAL3,BCAS1,PKNOX2,CSPG5,SNAP25,PALLD,DKK3,MYBPC1,KIF1B,LMO3,C11orf87,ZNF302,CAMTA1,CACNA1A,CACNA1E,CACNB2,EML4,VXN,GRIA2,OLR1,TMEM257,PAH,PCDH9,SEZ6L,PRMT8,PDE4B,CCSER2,BTF3L4,MFSD4A,CHD1L,RNF14,CRLS1,PPP2R5C,KCNT2,RBPJ,PRKACB,DOCK7,DZIP3,NRSN1,ANKS1B,TOMM20,LRRTM3,ITGAV,CADM2,PRDM2,HP1BP3,PTPRE,PLPPR4,ARNT2,RAD52,GNE,DTNA,SLC6A15,ZYG11B,FAM135B,ATL1,VWA5A,ELAVL4" MicroRNA hsa-miR-363*:mirSVR_lowEffct hsa-miR-363*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.32E-32 3.96E-28 7.19E-31 6.60E-30 92 1640 "SDE2,ASIC1,SYT9,EXTL1,ADAR,F3,PNMA8B,HPCAL4,MOBP,TRIM46,AMPH,CNIH2,ITSN1,NTNG1,MAGI3,CACHD1,JAKMIP3,SLC7A14,MSR1,PKNOX2,SLC8A3,MT3,SCMH1,GPR153,ADGRA1,SNAP25,ATP1A2,ATP2B2,PALLD,GABBR1,SCN3B,USP33,KIF21B,ENKUR,JPH4,B4GALNT1,NPAS3,NFASC,C11orf87,SMOC1,GFAP,RHBDL3,NHLH1,NKX2-2,GNG3,GNG4,WWC1,PRUNE2,NRGN,CECR2,SYT6,GRIN1,ATP13A2,OPCML,CELF3,ZDHHC22,TNFRSF1B,PFKFB3,CAMKV,NMT2,FADS2,FTO,PMP2,NSD2,ATCAY,POU3F2,RGS6,RIMS4,RBPJ,USP54,ECE2,KIAA0408,PSD,ANKS1B,LRRTM3,CA10,STMN4,PTPRE,SV2A,RABGAP1L,KCNK1,PCDH15,KCNMA1,SNX27,NKAIN1,PID1,DPP6,FAM13C,CAMK1G,RFX5,ABI2,EPB41L1" MicroRNA hsa-miR-1975:mirSVR_lowEffct hsa-miR-1975:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.78E-32 4.21E-28 7.63E-31 7.00E-30 86 1436 "ABAT,MAPT,PAQR6,WLS,ADARB2,CLIP1,SORCS1,SNX32,ASIC4,HPCAL4,ASRGL1,RASA3,CNIH2,NTNG1,JAKMIP3,SLC1A6,LRRC55,SLC8A2,SLCO1A2,SMARCE1,ATP1A2,ATP1A3,WDTC1,ZSWIM8,EMC1,CPLX2,NASP,LMO3,NELL1,NEUROD1,GANAB,RND1,C1QC,WWC1,TMEM136,TBX15,TCF12,PTBP2,TMEM151B,VSTM2A,GRIA4,GRID1,CELF3,ZDHHC22,ZFP91,KCNK10,CDC42,TNS1,ARHGAP19,LGI1,MAGI1,PDE2A,PDE4B,MS4A7,ARHGAP22,SLC22A6,NRXN2,FADS2,CELF5,RNF14,CRLS1,NKAIN4,ATRNL1,PRKAB2,SDC3,CTNND2,MASP1,DPYSL5,SYNC,CSDE1,BLOC1S6,SRGAP3,RABGAP1L,KCNK2,PCDH15,HS3ST4,SLC17A6,FAM66C,FAM57B,DPP6,RAP1GAP,SFXN5,SIDT2,SH3GLB1,RPRD1A,FGFBP3" MicroRNA hsa-miR-196a:mirSVR_lowEffct hsa-miR-196a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.79E-32 4.22E-28 7.63E-31 7.00E-30 81 1272 "RABEPK,ACER3,CNTNAP3,LGR4,FAM43B,WLS,CLIP1,GALNT13,SLC44A5,CHST15,ELMOD1,AQP4,SLC1A7,ASCL1,SLCO1A2,B3GAT1,TMEM108,TNIK,ARPP21,TTLL9,NDUFA5,STOX1,NCDN,ADHFE1,ACSBG1,PRUNE2,AZIN2,AKNA,RFFL,ADAMTS8,CCKBR,CRB1,TGFBR3,P2RX7,MAEL,PCDH8,CDH8,PDE2A,ADGRG1,HMGB1,PFKFB3,ASIC3,TUB,CCSER2,DNAJC12,FLRT1,CELF5,NSD2,MFSD4A,ETNPPL,RGS6,KCNT2,DZIP3,FMN2,PRKCZ,CTNND2,NRSN1,MASP1,TOMM20,PLPPR5,LRRTM3,ITGAV,BDNF-AS,PRDM2,COPS7A,CSDE1,BLOC1S6,KCNA1,SRGAP3,PCDH15,DLG2,PARP11,DSCAM,BSDC1,ZYG11B,RET,RFX4,FAM135B,ZNF248,ABI2,UEVLD" MicroRNA hsa-miR-9-5p:TargetScan hsa-miR-9-5p TargetScan 9.16E-32 4.96E-28 8.95E-31 8.21E-30 72 997 "ABAT,ASIC1,ACTN2,FAM43B,LDLRAD3,ARID1A,ADARB2,AMER2,FOXRED2,NLGN4X,CHST15,FGF14,FOXG1,ANK2,PKP4,NTNG1,GPAM,KIAA1614,RPH3A,CCDC88A,GPR153,ILDR2,B4GALNT1,ARPP21,NFASC,COLGALT2,GFAP,PHLDB1,NFIA,DDHD2,MYRF,CACNA1E,CACNB2,GPR26,PTBP2,CECR2,PSD3,GRIK3,OPCML,FBXL16,GUCY1A2,KCNK10,PCDH9,RBFOX2,PCSK2,PDE3B,PIRT,GPR37L1,ACOT7,BEST3,KIAA1549L,NMT2,CCSER2,PRRX1,PACSIN1,MICAL2,OSBPL3,RIMS3,PTCH1,JAKMIP2,KCNA1,KCNN3,RAB3IL1,RAB5B,RALGDS,ABI1,GOPC,FAM13C,FAM135B,ELAVL4,EN2,RCAN2" MicroRNA hsa-miR-185:mirSVR_highEffct hsa-miR-185:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-31 5.53E-28 9.96E-31 9.14E-30 83 1342 "ATAT1,ARID1A,WLS,MDM4,DSCAML1,SLITRK1,HOGA1,ASIC4,FGR,MOG,USP28,MIER1,MSRA,SORCS3,SNAP25,ATP1A3,SOX5,CADM3,AHCYL1,TTLL9,ADGRB2,CLASP2,NDUFA5,SMOC1,INKA2,PHLDB1,ZNF638,ASTN2,DCLK2,GOLGB1,PRUNE2,TCF12,PTBP2,VXN,GRIA2,GRIA4,USP2,TJP1,TMEM257,MAEL,CDC42,TNR,PCDH9,PTGDR2,LGI1,ZNF384,PDE1C,ACOT7,CA14,CASC2,JAM2,CCSER2,BEST1,SLC36A4,FAAP20,SF1,PPP2R5C,FEZ1,OSBPL3,NCAN,PRKACB,CTNND1,NRSN1,PSMD13,CA10,HP1BP3,ZC3H11A,SMG7,PTPRE,NAV2,KCNN3,FAM66C,PARP11,DTNA,ABCC9,CAMK1G,FAM135B,INSYN2,RBM12,RPRD1A,GPR61,RPE65,EPB41L1" MicroRNA hsa-miR-93:PITA hsa-miR-93:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-106b:PITA hsa-miR-106b:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-106a:PITA hsa-miR-106a:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-20b:PITA hsa-miR-20b:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-20a:PITA hsa-miR-20a:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-17:PITA hsa-miR-17:PITA_TOP PITA 1.05E-31 5.69E-28 1.01E-30 9.30E-30 65 800 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-106a*:mirSVR_highEffct hsa-miR-106a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-31 5.70E-28 1.01E-30 9.31E-30 74 1059 "EYA1,ARID1A,CLIP1,ADD3,WAC,SORCS1,TOMM40L,LINC00461,KIAA1109,ERICH3,CDC42BPA,USP28,SESN3,NTNG1,SORBS1,BCAS1,MIER1,CCDC88A,CADPS,SPHKAP,ASTN1,RCOR3,SNAP25,ATM,ATP1A2,EIF4G3,PALLD,GABBR1,SOX1,KIF1B,NASP,NCAM1,C11orf87,NDUFA5,RGL1,FAM168A,ZNF638,CAMTA1,ADGRL3,GOLGB1,TBX15,CLEC9A,PTBP2,GRIA2,GRIA4,TGFBR3,TPM3,MAGI1,PDE1A,HMGB1,CADM1,TJP2,C11orf49,PPP3CB,ATRNL1,PROX1,GON4L,PLPPR5,TUBB2B,CADM2,PRDM2,STMN4,PCDH15,KCNN3,C12orf4,RTN4,ABCC9,RFX4,INSYN2,SLC39A12,SLC4A10,ELAVL4,EN2,BAALC" MicroRNA hsa-miR-2114:mirSVR_lowEffct hsa-miR-2114:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-31 6.48E-28 1.15E-30 1.06E-29 84 1378 "TTYH1,LOC100128239,LGR4,RTN3,ADGRV1,ATAT1,RTKN,ADAR,ADD3,CDC7,ERMN,FCGR1A,CHST15,HOGA1,SCN4B,LRRTM4,SEMA6A,SEMA6C,CDC42BPA,ANK1,ANK2,ANXA7,SH3GL2,APBB1,MAGI3,ST3GAL3,SHTN1,ZNF365,URGCP,SLC2A5,BCO1,ARFGAP2,ASTN1,PALLD,SON,TNIK,KIF21B,ARPP21,NCDN,RCOR2,PHLDB1,NFIA,CASTOR3,CAMTA1,CDK5R2,TMEM136,GPM6A,PTBP2,VXN,SYT6,NUMA1,RFFL,CRB1,TMEM25,P2RX7,PTGDR2,SEZ6L,LGI1,LRTM2,NMT2,ST8SIA5,BEST1,NSD2,PPP3CB,FEZ1,KIAA0408,RIMS3,ANKS1B,HP1BP3,BLOC1S6,PTPRE,PARD6A,SV2A,PEX5,SNX27,FAM66C,DPP6,RALGDS,NUP214,RFX5,FAM135B,PIANP,SLC4A10,EPB41" MicroRNA hsa-miR-519d:PITA hsa-miR-519d:PITA_TOP PITA 1.21E-31 6.57E-28 1.17E-30 1.07E-29 65 802 "F3,WAC,AMER2,GPR158,SCN3A,USP28,MAGI3,SLITRK3,SHTN1,SLC1A2,RUFY2,YPEL4,CAPRIN2,ATP2B2,PALLD,MYT1L,B3GALT2,NPAS3,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,ARHGEF7,NHLH1,CAMTA1,ZFP91,REPS2,HPS5,TNS1,RBFOX2,PDE3B,PFKFB3,CCSER2,SLC25A27,PRRX1,ACBD5,POU3F2,PNKD,CHD5,PKN2,NRSN1,PSD,DPYSL5,CA10,CADM2,HP1BP3,RGMA,CEP170,CSDE1,MAGI2,KCNA1,PTPRD,PTPRO,KCNJ10,WIPF2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,SFXN5,ARHGAP12,TMEM100,EPB41" MicroRNA hsa-miR-302c:mirSVR_highEffct hsa-miR-302c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.36E-31 7.36E-28 1.30E-30 1.20E-29 87 1481 "EPS8,LGR4,MDM4,RTN1,AMER2,GPR158,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,ASPH,RCOR3,EIF4G3,MEGF11,MYT1L,TNIK,CAB39,ARPP21,LMO3,CLASP2,DCAF5,RGL1,NEUROD1,SLCO1C1,ARHGEF7,ZNF638,CAMTA1,UNC5D,ADGRL3,GPM6A,TCF7L2,ZEB1,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,TGFBR3,AIFM1,MAEL,HPS5,TNS1,PCDH9,PCSK2,MAGI1,PRMT8,HMGB1,FAM181B,PRRX1,SPATA6,ACBD5,CNRIP1,SNCAIP,PPP3CB,KCNT2,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRDM2,PRTFDC1,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRO,RABGAP1L,KCNMA1,HS3ST4,RAB5B,DNM2,FAM13C,DTNA,PAK5,SLC6A15,CRTAC1,TMEM100" MicroRNA hsa-miR-367:mirSVR_highEffct hsa-miR-367:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.42E-31 7.71E-28 1.36E-30 1.25E-29 74 1064 "ABAT,RBM10,TMEM74,ACTN2,CSMD2,CSMD3,KLHL32,DSCAML1,GRAMD1B,GPR158,SCN3A,KIAA1109,ANK3,USP28,SESN3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,B3GALT2,IDI2-AS1,KIF1B,NPAS3,RGL1,NEUROD1,AJAP1,PCDH11X,ZNF638,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,LILRA1,CAMK2A,VSTM2A,GRIA1,GRIA4,RFFL,CRB1,P2RX7,AIFM1,CDH10,TPM4,PDE1A,SCRG1,CCSER2,CNRIP1,CRLS1,KCNT2,ATRNL1,VCAN,FMN2,USP54,EDRF1,GON4L,ITGAV,PMEPA1,CADM2,LRP8,PTPRD,PLPPR4,PTPRO,PEX5,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65,BAALC" MicroRNA hsa-miR-571:mirSVR_lowEffct hsa-miR-571:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-31 9.27E-28 1.63E-30 1.50E-29 83 1352 "EPS8,MAP6,SYT9,SYNDIG1,MRVI1,ADCY2,GRAMD1B,SNX30,CHST15,LRRTM4,FHL1,MOBP,SOX6,AMPH,ITSN1,BCAS1,AQP4,CCDC88A,SCMH1,ASPH,TMEM108,IGSF9B,SCN3B,SON,NMNAT2,RAP1GAP2,COLGALT2,ALDH1L1,ERBIN,CASTOR3,NKX2-2,KAZN,WWC1,TCF7L2,HAP1,GRIA1,GRIA4,PADI2,HRH3,PDE4B,PIRT,HMGB1,PFKFB3,ASIC3,TJP2,PMP2,SLC25A27,NSD2,MFSD4A,SF1,CRMP1,SNCAIP,MICAL2,PRKAB2,PRKCG,CTNND1,NRSN1,HES5,FAM131B,PROX1,WBP1L,DPYSL5,SYNC,CA10,PRDM2,COPS7A,CEP170,MAGI2,PTPRE,KCNC1,KCNJ11,DLG2,RALGDS,C12orf4,DTNA,SLC6A15,ZYG11B,RFX5,VANGL2,PIANP,FGFBP3,EPB41,EPB41L1" MicroRNA hsa-miR-22*:mirSVR_highEffct hsa-miR-22*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-31 9.27E-28 1.63E-30 1.50E-29 83 1352 "ACLY,RTKN,MDM4,ADD3,GRAMD1B,NLGN4X,FCGR1A,SCN3A,ELMOD1,TRIM46,SGIP1,ANK2,PPFIA1,ITSN1,NLGN1,BCAS1,MIER1,LRRC55,CCDC88A,ASCL1,RCOR3,SNCB,EIF4G3,PHYHIPL,DKK3,AHCYL1,TTLL9,KIF1B,NPAS3,ERBIN,SLCO1C1,GLS,ZNF638,SYT4,SEMA4A,CAMTA1,UNC5D,KLHL4,ANO4,TCF7L2,ZEB1,NUDT21,VSTM2A,BRSK2,GRIA4,GPR88,ZDHHC22,ATG4C,PADI2,PDE1A,PDE4B,LINC01102,HNRNPK,NLGN3,FAM181B,CNTN1,SLC25A27,BEST1,BTF3L4,CP,SNCAIP,RGS6,RBPJ,PRKAB2,RAB39A,PKN2,MAPK8,ECE2,MASP1,PLPPR1,JAKMIP2,MAGI2,BLOC1S6,C1orf109,RABGAP1L,KCNK2,PCDH15,DLG2,DTNA,RGS7,RLBP1,SEC61A2,ELAVL4" MicroRNA hsa-miR-30a:PITA hsa-miR-30a:PITA_TOP PITA 1.80E-31 9.72E-28 1.70E-30 1.56E-29 67 863 "ARID1A,CSMD3,SNX30,SCN3A,SEMA6A,FOXG1,ITSN1,PPM1E,DOCK10,MAGI3,DGKZ,DGKD,NLGN1,SLC1A2,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,ATP2B2,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,CECR2,GRIA2,GRM3,OMG,TLL2,CELF3,PCDH9,LGI1,ZMYND8,PIK3CD,MICAL1,PNKD,OSBPL3,ATRNL1,DOCK7,CTNND2,FAM131B,TOX,WBP1L,TOMM20,CA10,JAKMIP2,CEP170,MAGI2,PTPRD,SRGAP3,RALGDS,PAK5,TTLL7,RNF220,EFNA3,RBM12,ELAVL3,EPB41,EPB41L2" MicroRNA hsa-miR-30d:PITA hsa-miR-30d:PITA_TOP PITA 1.80E-31 9.72E-28 1.70E-30 1.56E-29 67 863 "ARID1A,CSMD3,SNX30,SCN3A,SEMA6A,FOXG1,ITSN1,PPM1E,DOCK10,MAGI3,DGKZ,DGKD,NLGN1,SLC1A2,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,ATP2B2,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,CECR2,GRIA2,GRM3,OMG,TLL2,CELF3,PCDH9,LGI1,ZMYND8,PIK3CD,MICAL1,PNKD,OSBPL3,ATRNL1,DOCK7,CTNND2,FAM131B,TOX,WBP1L,TOMM20,CA10,JAKMIP2,CEP170,MAGI2,PTPRD,SRGAP3,RALGDS,PAK5,TTLL7,RNF220,EFNA3,RBM12,ELAVL3,EPB41,EPB41L2" MicroRNA hsa-miR-30b:PITA hsa-miR-30b:PITA_TOP PITA 1.80E-31 9.72E-28 1.70E-30 1.56E-29 67 863 "ARID1A,CSMD3,SNX30,SCN3A,SEMA6A,FOXG1,ITSN1,PPM1E,DOCK10,MAGI3,DGKZ,DGKD,NLGN1,SLC1A2,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,ATP2B2,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,CECR2,GRIA2,GRM3,OMG,TLL2,CELF3,PCDH9,LGI1,ZMYND8,PIK3CD,MICAL1,PNKD,OSBPL3,ATRNL1,DOCK7,CTNND2,FAM131B,TOX,WBP1L,TOMM20,CA10,JAKMIP2,CEP170,MAGI2,PTPRD,SRGAP3,RALGDS,PAK5,TTLL7,RNF220,EFNA3,RBM12,ELAVL3,EPB41,EPB41L2" MicroRNA hsa-miR-30e:PITA hsa-miR-30e:PITA_TOP PITA 1.80E-31 9.72E-28 1.70E-30 1.56E-29 67 863 "ARID1A,CSMD3,SNX30,SCN3A,SEMA6A,FOXG1,ITSN1,PPM1E,DOCK10,MAGI3,DGKZ,DGKD,NLGN1,SLC1A2,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,ATP2B2,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,CECR2,GRIA2,GRM3,OMG,TLL2,CELF3,PCDH9,LGI1,ZMYND8,PIK3CD,MICAL1,PNKD,OSBPL3,ATRNL1,DOCK7,CTNND2,FAM131B,TOX,WBP1L,TOMM20,CA10,JAKMIP2,CEP170,MAGI2,PTPRD,SRGAP3,RALGDS,PAK5,TTLL7,RNF220,EFNA3,RBM12,ELAVL3,EPB41,EPB41L2" MicroRNA hsa-miR-30c:PITA hsa-miR-30c:PITA_TOP PITA 1.80E-31 9.72E-28 1.70E-30 1.56E-29 67 863 "ARID1A,CSMD3,SNX30,SCN3A,SEMA6A,FOXG1,ITSN1,PPM1E,DOCK10,MAGI3,DGKZ,DGKD,NLGN1,SLC1A2,PKNOX2,SLC6A9,DACH2,CADPS,SPHKAP,SORCS3,ATP2B2,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,CECR2,GRIA2,GRM3,OMG,TLL2,CELF3,PCDH9,LGI1,ZMYND8,PIK3CD,MICAL1,PNKD,OSBPL3,ATRNL1,DOCK7,CTNND2,FAM131B,TOX,WBP1L,TOMM20,CA10,JAKMIP2,CEP170,MAGI2,PTPRD,SRGAP3,RALGDS,PAK5,TTLL7,RNF220,EFNA3,RBM12,ELAVL3,EPB41,EPB41L2" MicroRNA hsa-miR-149*:mirSVR_highEffct hsa-miR-149*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-31 1.05E-27 1.82E-30 1.67E-29 70 950 "RABEPK,MAP6,ASIC1,SYT9,FAM43B,ATAT1,KCNIP2,CSMD3,ADAR,SORCS1,HOGA1,FOXG1,AMPH,GPAM,SYBU,BCAS1,API5,ZNF365,SLC2A5,BCO1,PKNOX2,MT3,BRINP2,EIF4G3,PHYHIPL,TNIK,KIF21B,JPH4,NFASC,COLGALT2,GANAB,ARHGEF7,VAMP1,NHLH1,SEMA4A,GNAS,ANO4,TBX15,TCF7L2,NRGN,GRID1,RFFL,ZDHHC22,PADI2,HPSE2,GDAP1L1,A2ML1,FAM181B,CCDC136,BEST1,BTF3L4,SPATA6,NSD2,MICAL2,NCAN,PRKCG,FGFR1OP2,PRDM2,LRP8,COPS7A,CSDE1,NTM,CAB39L,RAB5B,KLRC3,FAM66C,DTNA,PAK5,NUP214,RGR" MicroRNA hsa-miR-190:mirSVR_highEffct hsa-miR-190:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-31 1.10E-27 1.92E-30 1.76E-29 78 1194 "ACER3,CNTNAP3,KLHL32,SLITRK1,LINC00461,FGF14,FHL1,SH3GL2,GPAM,NLGN1,MIER1,BCO1,RUFY2,SLC14A1,DACH2,ASTN1,RCOR3,C10orf105,NRG3,PHYHIPL,TNIK,CAB39,ARPP21,SALL3,RGL1,NEUROD1,RND1,PCDH11X,SYT4,DCLK2,ANO4,PRUNE2,LRIT2,TCF12,GRIA4,GRIK3,CRB1,PAH,PAX6,CDC42,PCDH9,TPD52,PDE3B,PRMT8,ZMYND8,BEST3,CASC2,CADM1,NRXN1,NEGR1,BTF3L4,COL9A2,P2RY12,MED1,PPP2R5C,PPP3CB,ATRNL1,PLD5,ZBTB16,PLPPR5,CA10,BDNF-AS,PTHLH,PRDM2,CEP170,CSDE1,MAGI2,KCNA4,AK5,PCDH15,C12orf4,SUSD4,DTNA,ZYG11B,SSPN,RBM12,RPRD1A,BAALC" MicroRNA hsa-miR-384:mirSVR_lowEffct hsa-miR-384:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-31 1.24E-27 2.15E-30 1.98E-29 95 1772 "MAP6,CDHR1,ATAT1,WLS,ADAR,DSCAML1,SLITRK1,SORCS1,ERMN,GPR158,LINC00461,FGF14,GOLGA7B,MOBP,ITSN1,PPM1E,SLITRK3,ST3GAL3,AQP4,ZNF365,MIER1,SLC2A5,PKNOX2,NSG2,DACH2,SCMH1,PDE8B,CAPRIN2,BRINP2,ASTN1,SMARCE1,RCOR3,ATP1A2,NRG3,NMNAT2,NASP,SPART,CLASP2,SEPT3,CASTOR3,ZNF638,CAMTA1,ADGRL3,TCF12,PTBP2,CAMK2G,CECR2,LINC00839,INA,TJP1,PAX6,RBFOX2,PDE3B,CASC2,MS4A7,HNRNPK,NLGN3,FTO,ATCAY,POU3F2,SNCAIP,KCNT2,FEZ1,DOCK7,PRKCZ,CTNND2,NRSN1,MASP1,RIMS3,GON4L,ZNF385B,LRRTM3,HP1BP3,CEP170,MAGI2,ZC3H11A,OCIAD1,SRGAP3,KCNJ9,RABGAP1L,TMCC2,PCDH15,PEX5,ATN1,DBX2,ABCC9,SLC6A15,RGS10,RLBP1,SSPN,ABI2,SLC4A10,RPE65,TMEM100,PRRT4" MicroRNA hsa-miR-491-3p:mirSVR_lowEffct hsa-miR-491-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-31 1.30E-27 2.26E-30 2.07E-29 88 1527 "TTYH1,SDE2,ZFYVE27,ACER3,LGR4,ARID1A,WLS,MDM4,CSMD3,KLHL32,WAC,SORCS1,AMER2,FOXRED2,FOXG1,USP28,ITSN1,ANXA7,PKP4,MIER1,SLC7A14,SLC8A3,CCDC88A,SHANK2,CSPG5,RCOR3,MEGF11,DKK3,SCN3B,SOX1,ENKUR,B4GALNT1,LHFPL4,ADGRB2,DNER,NASP,LMO3,NEUROD1,AJAP1,GLS,ADGRL3,GOLGB1,VWC2,TCF7L2,ZEB1,NUMA1,RFFL,GPR88,CRB1,HRH3,MAGI1,LINC01102,ZMYND8,ANLN,DNAJC12,CNTN1,MEAF6,NXPH1,MED1,SNCAIP,PPP3CB,RBPJ,RAB39A,PLPP4,PLD5,NRSN1,PUM1,EDRF1,SYTL2,GON4L,CADM2,COPS7A,KCNA4,PTPRD,KCNA6,KCNH1,RABGAP1L,KCNK1,PCDH15,DLG3,PID1,PLEKHB2,RAD52,C12orf4,DBX2,PAK5,ARHGEF10L,SH3GLB1" MicroRNA hsa-miR-26b:mirSVR_lowEffct hsa-miR-26b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-31 1.31E-27 2.26E-30 2.08E-29 99 1919 "ACER3,TMEM74,EYA1,MRVI1,ARID1A,WLS,F3,KLHL32,WAC,NLGN4X,SLC44A5,FCGR1B,LRRC7,MOBP,SELL,AMPH,ASRGL1,ANK2,PPFIA1,ITSN1,PKP4,NTNG1,MAGI3,GPAM,SLITRK3,ST3GAL3,API5,MSRA,LRRC55,ARHGAP5,SHANK2,SLIT1,ASPH,ATM,PHYHIPL,KIF21B,ADHFE1,NEUROD1,SEPT3,PCDH11X,DDHD2,CAMTA1,ANO4,GPM6B,TCF12,NUDT21,CECR2,PSD3,GRIA2,GRIK2,OPCML,TMEM25,GUCY1A1,KCNK10,C1orf94,SEZ6L,TPD52,PDE4B,PDYN,SCRG1,CHRNB2,HNRNPK,TMEFF2,GDAP1L1,PIK3CD,A2ML1,VAV2,BEST1,NSD2,CP,ATRNL1,PRKAB2,PRKACB,DOCK7,FMN2,PUM1,EDRF1,KIAA0408,TOX,ZNF385B,PTCH1,BDNF-AS,ELMO1,OCIAD1,PTPRE,KCNH1,RABGAP1L,PCDH15,CAB39L,PID1,SLC17A6,ATG16L1,ABI1,ABCC9,RET,SEC61A2,SSPN,RPE65,SEZ6" MicroRNA hsa-miR-599:mirSVR_lowEffct hsa-miR-599:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.80E-31 1.51E-27 2.62E-30 2.40E-29 93 1705 "EPS8,RPL38,MAP6,TMEM74,LGR4,MRVI1,CSMD2,ARID1A,CSMD3,CLIP1,GALNT13,LRRC7,FGF14,SOX6,ANK1,ANK3,NTNG1,SLITRK3,MIER1,SLC8A3,NSG2,ASPH,MTR,SMARCE1,SNAP25,ATM,PHYHIPL,WDTC1,ZCCHC24,NMNAT2,KIF1B,C11orf87,NDUFA5,NEUROD1,SEPT3,NFIA,PCDH11X,KAZN,GNAS,GNG4,CNTN2,ADGRL3,GPM6B,VWC2,DDR1,GRIA1,GRID1,OPCML,CCKBR,CRB1,INA,TLL2,DAAM2,PAX6,CDC42,PADI2,RBFOX2,TPM3,ZMYND8,ANO5,PLEKHB1,JAM2,A2ML1,VAV2,BTF3L4,NXPH1,MFSD4A,PPP3CB,RGS6,KCNT2,MICAL2,OSBPL3,ATRNL1,PRKCZ,KIAA0408,PLPPR1,NTM,PCDH15,KCNMA1,PEX5,SNX27,DLG2,KIF2A,DNAH9,KLRC3,PARP11,RGS7,ARHGEF10L,ABI2,VWA5A,ELAVL3,ELAVL4,RPE65" MicroRNA hsa-miR-1826:mirSVR_lowEffct hsa-miR-1826:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.83E-31 1.53E-27 2.64E-30 2.42E-29 84 1395 "SERPINA3,ACER3,MBP,CNTNAP3,MEG3,MRVI1,ARID1A,CSMD3,WAC,ERMN,TMEM156,SLC44A5,TESK2,LINC00461,SEMA6A,MOBP,ITSN1,SESN3,SORBS1,SHTN1,PAAF1,AQP4,RUFY2,SLCO1A2,DLL3,ASPH,NRG3,CAB39,ARPP21,NAP1L2,NASP,NCAM1,C11orf87,NELL1,KIRREL3,GJB1,AJAP1,GLS,PCDH11X,LUZP2,ROBO3,CDK5R2,ADGRL3,TMEM136,GPM6B,AZIN2,VSTM2A,NUMA1,GRIK2,ZFP91,MAEL,PAX6,DCLK1,TPM4,PCSK2,PDE3B,HMGB1,ANO5,JAM2,GDAP1L1,PRRX1,NXPH1,ACBD5,TENM4,ATRNL1,TOX,WBP1L,JAKMIP2,BDNF-AS,CNIH3,CEP170,BLOC1S6,KCNA6,SRGAP3,DLG2,CAB39L,WIPF2,C12orf4,SUSD4,BSDC1,ABCC9,SLC6A15,ZYG11B,RNF220" MicroRNA hsa-miR-342-5p:mirSVR_lowEffct hsa-miR-342-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.16E-31 1.71E-27 2.95E-30 2.70E-29 73 1047 "MAG,RABEPK,APC2,SYT9,LDLRAD3,ADARB2,GALNT13,WAC,FOXRED2,FGF14,FOXM1,TRIM46,CNIH2,ITSN1,NTNG1,GPAM,ST3GAL3,SLC1A7,MT3,SCMH1,DLL3,TMEM151A,SNCB,PALLD,KIF21B,ZSWIM8,NMNAT2,B4GALNT1,ADAM15,CPLX2,NCAM1,LMO3,ALDH1L1,INKA2,FGF17,ARHGEF7,C1QC,GNAS,GNG4,AZIN2,VSTM2A,BRSK2,GRIN1,ATP13A2,AIFM1,PADI2,PTGDR2,ANO5,ASIC3,HPCA,NLGN3,NOMO2,CPT1C,FTO,CELF5,PPP3CB,RGS6,MICAL2,OSBPL3,NRSN1,WBP1L,DPYSL5,JAKMIP2,SV2A,SNX27,PARP11,RALGDS,L1CAM,TTLL7,VANGL2,SIDT2,EFNA3,RASGRP2" MicroRNA hsa-miR-181a:PITA hsa-miR-181a:PITA_TOP PITA 3.56E-31 1.93E-27 3.30E-30 3.03E-29 65 817 "EPS8,MAPT,SLC25A25,CLIP1,SLITRK1,ERMN,SOX6,CDC42BPA,ANK1,ITSN1,DOCK10,GAS7,API5,MADD,PKNOX2,CAPRIN2,SNAP25,ATP2B2,PALLD,MEGF11,SOX5,NMNAT2,LMO3,DCAF5,SEPT3,UNC5D,PTBP2,CAMK2G,CECR2,PSD3,GRIA2,GRIK2,GPR88,KCNK10,TNS1,DCLK1,PDE3B,KIAA1549L,NRXN1,NEGR1,NMT2,CCSER2,FAT3,POU3F2,SF1,TENM4,OSBPL3,ATRNL1,DOCK7,PUM1,PROX1,TOX,BLOC1S6,ZC3H11A,PTPRE,ARNT2,KCNMA1,DPP6,ABI1,PAK5,ST8SIA3,TTLL7,LMO1,SLC4A10,EN2" MicroRNA hsa-miR-181c:PITA hsa-miR-181c:PITA_TOP PITA 3.56E-31 1.93E-27 3.30E-30 3.03E-29 65 817 "EPS8,MAPT,SLC25A25,CLIP1,SLITRK1,ERMN,SOX6,CDC42BPA,ANK1,ITSN1,DOCK10,GAS7,API5,MADD,PKNOX2,CAPRIN2,SNAP25,ATP2B2,PALLD,MEGF11,SOX5,NMNAT2,LMO3,DCAF5,SEPT3,UNC5D,PTBP2,CAMK2G,CECR2,PSD3,GRIA2,GRIK2,GPR88,KCNK10,TNS1,DCLK1,PDE3B,KIAA1549L,NRXN1,NEGR1,NMT2,CCSER2,FAT3,POU3F2,SF1,TENM4,OSBPL3,ATRNL1,DOCK7,PUM1,PROX1,TOX,BLOC1S6,ZC3H11A,PTPRE,ARNT2,KCNMA1,DPP6,ABI1,PAK5,ST8SIA3,TTLL7,LMO1,SLC4A10,EN2" MicroRNA hsa-miR-892b:mirSVR_lowEffct hsa-miR-892b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-31 2.05E-27 3.52E-30 3.23E-29 90 1606 "ABAT,MAP6,CEND1,ADGRV1,LDLRAD3,AMER2,FOXRED2,TOMM40L,HOGA1,TESK2,DISP3,LRRC7,GOLGA7B,ERICH3,ANK3,PPFIA1,MAGI3,NLGN1,LRRC55,ASCL1,CGREF1,DNAH17,SORCS3,TMEM108,ATP1A2,EIF4G3,PALLD,MEGF11,DKK3,SON,SOX5,KIF21B,B4GALNT1,KIF1B,NFASC,CLASP2,ZNF302,NELL1,PCDH11X,KAZN,ROBO3,TMEM136,ANO4,CACNA1E,DDR1,CACNB2,TCF12,NUDT21,GRIA1,GRIA4,GRID1,GRIK2,CRB1,TLL2,REPS2,PADI2,PCDH9,DCLK1,PTGDR2,RBFOX2,ARHGAP19,PDE2A,HMGB1,MS4A7,CADM1,SEMA5B,TJP2,C11orf49,PRRX1,PTPA,PPP2R5C,TOX,SPIRE1,PTCH1,JAKMIP2,PMEPA1,COPS7A,KCNA1,SMG7,PTPRE,KCNH1,RABGAP1L,KCNJ10,KCNN3,OLIG1,RALGDS,ZYG11B,NUP214,YY1AP1,C2orf80" MicroRNA hsa-miR-20b*:mirSVR_lowEffct hsa-miR-20b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.91E-31 2.12E-27 3.62E-30 3.32E-29 85 1435 "ABAT,ACHE,RCSD1,ATAT1,SNX30,SNX32,LINC00461,BCAR3,GOLGA7B,MOBP,TRIM46,ERICH3,ITSN1,PPM1E,APBA2,SORBS1,CACHD1,PAAF1,MSR1,MSRA,CCDC88A,SLC14A1,ZSWIM8,NMNAT2,TTLL9,KIF1B,DNER,NAP1L2,SPART,LMO3,CLASP2,NDUFA5,STOX1,SEPT3,LUZP2,GNAS,PSRC1,TMEM136,TBX15,ACSL6,VWC2,LILRA1,CLEC9A,TCF12,PTBP2,CAMK2G,VXN,VSTM2A,GRIA1,TMEM25,P2RX7,REPS2,PTGDR2,ARHGAP19,BEST3,ANO5,PFKFB3,NRXN1,SPATA6,NSD2,SNCAIP,PPP3CB,KCNT2,FEZ2,MICAL2,OSBPL3,VCAN,PLPP4,PKN2,ANKS1B,GON4L,RABGAP1L,NAV2,DLG2,KIF2A,DNM2,ATG16L1,ZYG11B,RFX4,JMJD1C,SEC61A2,ARHGAP12,RCAN2,UEVLD,BAALC" MicroRNA hsa-miR-223:mirSVR_lowEffct hsa-miR-223:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.16E-31 2.25E-27 3.84E-30 3.53E-29 90 1608 "EPS8,LGR4,MEG3,CSMD2,WLS,RTKN,CSMD3,CDC7,ERMN,TOMM40L,LRRC7,MOBP,PPFIA1,NTNG1,SLC1A6,RPH3A,DACH2,SLN,ASTN1,TMEM108,ADGRA1,SON,B3GALT2,SOX5,NMNAT2,ARPP21,TTLL9,C11orf87,CLASP2,ALDH1L1,NDUFA5,NELL1,ADHFE1,SLCO1C1,ACSBG1,NFIA,DDHD2,CAMTA1,MYRF,ADGRL3,ZEB1,GPR17,EML4,CAMK2G,PSD3,GRIA1,GRIA2,OLR1,OPCML,LINC00839,CRB1,GUCY1A1,TLL2,PCDH9,CDH8,TPM3,PIRT,PDYN,HAPLN2,CADM1,ZFYVE9,CNTN1,MEAF6,BEST1,SPATA6,MFSD4A,SNCAIP,KCNT2,ATRNL1,PHACTR3,PRKACB,KIAA1755,USP54,CTNND2,NRSN1,KIAA0408,BRINP3,WBP1L,SPIRE1,DNAJC6,PLPPR4,SRGAP3,NTM,PCDH15,RAD52,FAM66C,DTNA,PAK5,JMJD1C,BAALC" MicroRNA hsa-let-7g:mirSVR_lowEffct hsa-let-7g:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.46E-31 2.41E-27 4.11E-30 3.77E-29 98 1897 "RABEPK,ACER3,CDHR1,MEG3,RTKN,GALNT13,SORCS1,ERMN,TUBB4A,TOMM40L,SNX32,HOGA1,SCN4B,ASIC4,HPCAL4,CDC42BPA,ANK1,ANK2,ANK3,PPFIA1,ITSN1,PPM1E,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,RUFY2,MSR1,SLC8A2,SLCO1A2,USP33,B3GALT2,TNIK,ZSWIM8,ADAM15,NPAS3,NDUFA5,MLC1,GOLGB1,ATF7,TCF12,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,PTPN5,TMEM25,FBXL16,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,GPR37L1,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,PRKACB,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,MED24,BLOC1S6,CDH20,PTPRD,KCNC1,RABGAP1L,TMCC2,FAM57B,DSCAM,RASGRF1,BSDC1,ABCC9,SLC6A15,NUP214,RBM12,ELAVL4,EPB41L2,UEVLD" MicroRNA hsa-miR-4252:mirSVR_lowEffct hsa-miR-4252:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.60E-31 2.49E-27 4.23E-30 3.88E-29 97 1861 "ZFYVE27,ASIC1,RTN3,ADGRV1,LDLRAD3,MDM4,ADCY2,GALNT13,HOGA1,KIAA1109,DISP3,FGF1,BCAR3,MOBP,ITSN1,API5,MSR1,PKNOX2,SLC8A3,ASCL1,SCG3,SPHKAP,CAPRIN2,DDX25,SORCS3,ASTN1,ATM,ATP1A2,ATP1A3,FYN,PALLD,SON,WDTC1,SOX5,KIF21B,ADAM15,NCAM1,SMOC1,NELL1,CASTOR3,MMD2,ADGRL3,TBX15,ACSL6,HAP1,NUDT21,CAMK2A,AKNA,GRM3,USP2,NEURL1,ZDHHC22,ZFP91,HPS5,CDH8,DCLK1,ARHGAP19,ZMYND8,FNDC5,DLGAP3,GDAP1L1,CAMKV,NMT2,CCDC136,PRRX1,IFFO1,NSD2,CNRIP1,MED1,PNKD,PPP2R5C,SNCAIP,ATRNL1,MAPK8,MAPK10,ECE2,KLK6,WBP1L,SPIRE1,DNAJC6,MAGI2,OLFM3,KCNJ10,KCNJ11,RAB5B,PLEKHB2,FAM66C,RASGRF1,DBX2,ABCC9,NUP214,RGR,INSYN2,VANGL2,SEC61A2,EN2,EPB41L1" MicroRNA "ACTGTGA,MIR-27A:MSigDB" "ACTGTGA,MIR-27A:MSigDB" MSigDB 4.70E-31 2.55E-27 4.31E-30 3.96E-29 50 447 "EYA1,SLITRK1,SEMA6A,ANK1,ANK2,PPM1E,APBA2,GPAM,SLC1A2,URGCP,SNAP25,WDTC1,ZCCHC24,CAB39,NEK6,NFASC,COLGALT2,SEPT3,CAMTA1,UNC5D,KLHL4,CACNB2,DIRAS1,TMEM25,MFSD2A,CDC42,NRXN1,CABP1,IFFO1,POU3F2,RGS6,EDRF1,ECE2,RIMS3,PLPPR5,CA10,ELMO1,KCNA6,SV2A,KCNK2,NAV2,NKAIN1,JMJD1C,VANGL2,LPAR6,ARHGAP12,EN2,EPB41,EPB41L1,RCAN2" MicroRNA "ACTGTGA,MIR-27B:MSigDB" "ACTGTGA,MIR-27B:MSigDB" MSigDB 4.70E-31 2.55E-27 4.31E-30 3.96E-29 50 447 "EYA1,SLITRK1,SEMA6A,ANK1,ANK2,PPM1E,APBA2,GPAM,SLC1A2,URGCP,SNAP25,WDTC1,ZCCHC24,CAB39,NEK6,NFASC,COLGALT2,SEPT3,CAMTA1,UNC5D,KLHL4,CACNB2,DIRAS1,TMEM25,MFSD2A,CDC42,NRXN1,CABP1,IFFO1,POU3F2,RGS6,EDRF1,ECE2,RIMS3,PLPPR5,CA10,ELMO1,KCNA6,SV2A,KCNK2,NAV2,NKAIN1,JMJD1C,VANGL2,LPAR6,ARHGAP12,EN2,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-300:mirSVR_highEffct hsa-miR-300:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.22E-31 2.83E-27 4.79E-30 4.39E-29 87 1509 "EPS8,ACLY,SYT9,WLS,CSMD3,ADORA3,NLGN4X,GPR158,TESK2,FGF1,ELMOD1,FOXG1,SFPQ,ERICH3,ANK3,PPFIA1,PPM1E,DGKD,SORBS1,SYBU,SHTN1,PAAF1,RUFY2,MSR1,ASPH,EIF4G3,PHYHIPL,ARPP21,NEK6,KIF1B,NAP1L2,LMO3,NEUROD1,GANAB,VAMP1,PCDH11X,POPDC3,ANO4,TBX15,CACNB2,LILRA1,ZEB1,CECR2,GRIA1,GRIA2,RFFL,GRM3,AIFM1,PCDH8,CDH10,PCSK2,MAGI1,PDE1C,HMGB1,NRXN1,CCSER2,BEST1,BTF3L4,ACBD5,FEZ2,OSBPL3,RBPJ,PRKACB,FMN2,ANKS1B,TOMM20,PTCH1,ITGAV,LRP8,BLOC1S6,ZC3H11A,KCNA4,OCIAD1,RABGAP1L,PCDH15,SNX27,DNM2,SLC17A6,DPP6,FAM13C,SLC6A15,ZNF248,RPRD1A,VWA5A,EPB41,EPB41L1,EPB41L2" MicroRNA hsa-miR-1253:mirSVR_highEffct hsa-miR-1253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.43E-31 2.94E-27 4.96E-30 4.55E-29 91 1649 "EPS8,MAP6,ACLY,ATAT1,WLS,RTN1,DSCAML1,NLGN4X,LRRC7,FGF14,ERICH3,ANK2,PPM1E,NLGN1,MIER1,SLC1A7,MADD,LRRC55,CCDC88A,DACH2,CADPS,DNAH17,DLL3,MTR,GABBR1,SCN3B,WDTC1,CAB39,AHCYL1,FXYD6,CLASP2,ERBIN,ZNF638,CDK5R2,ADGRL3,ANO4,ACSL6,HAP1,EML4,VSTM2A,GRIA4,OLR1,TMEM25,MFSD2A,INA,MAEL,PCDH9,TPM4,PDE1C,PDE4B,FNDC5,TMEFF2,CADM1,ANLN,BTF3L4,MFSD4A,MED1,RNF14,KCNT2,MICAL2,NCAN,PRKACB,KIAA1755,PKN2,PLD5,IGSF1,NRSN1,FGFR1OP2,PLPPR5,SYNC,DNAJC6,PLPPR1,CEP170,AK5,KCNMA1,PEX5,DLG2,NKAIN1,HS3ST4,C12orf4,FAM13C,DBX2,RFX4,RFX5,FAM135B,SEC61A2,RNF220,SIDT2,RPRD1A,FGFBP3,ARHGAP12" MicroRNA hsa-miR-583:mirSVR_highEffct hsa-miR-583:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.50E-31 2.98E-27 5.03E-30 4.61E-29 85 1442 "SDE2,PRR5L,CDHR1,ARID1A,KLHL32,WAC,SORCS1,GRAMD1B,AMER2,LRRTM4,FHL1,MOG,TRIM46,AMPH,ERICH3,ASRGL1,ANK2,USP28,APC,NTNG1,SORBS1,NLGN1,ST3GAL3,PAAF1,MIER1,DACH2,TAGLN3,SMARCE1,B3GAT1,NRG3,FYN,SON,TNIK,KIF1B,STOX1,ERBIN,RCOR2,RGL1,VAMP1,SYT4,CACNB2,TCF7L2,EML4,GRIA4,CRB1,MFSD2A,CDC42,PCDH9,PDE1C,SERPINE2,CADM1,CPT1C,ST8SIA5,SLC25A27,BEST1,FAAP20,PPP2R5C,SNCAIP,MICAL2,OSBPL3,NCAN,PHACTR3,NRSN1,NOS1AP,CA10,CEP170,PTPRD,SMG7,DLG2,DNAH9,DSCAM,RASGRF1,DTNA,PAK5,JMJD1C,FAM135B,SYT15,SEC61A2,EFNA3,VWA5A,CBLN2,SLC4A10,EN2,EPB41L2,RCAN2" MicroRNA hsa-miR-508-3p:mirSVR_lowEffct hsa-miR-508-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.32E-31 3.42E-27 5.76E-30 5.28E-29 87 1513 "EYA1,RTN1,ADCY2,NLGN4X,KIAA1109,LRRC7,SEMA6A,BBOX1,NTNG1,GPAM,NLGN1,LRRC4C,MIER1,SLC7A14,SLC8A3,CCDC88A,SMARCE1,ATM,ATP1A2,B3GALT2,SOX5,CAB39,ENKUR,SALL3,KIF1B,NFASC,ALDH1L1,DCAF5,RCOR2,SLCO1C1,NFIA,PCDH11X,OS9,DCLK2,GNAS,WWC1,GPM6B,FAM69C,TCF7L2,TCF12,AZIN2,PTBP2,CAMK2G,CDC42,PCDH8,PCDH9,RBFOX2,LGI1,PCSK2,PDYN,HMGB1,PFKFB3,HNRNPK,CAMKV,DNAJC12,MICAL1,NSD2,CNRIP1,NCAN,DOCK7,DZIP3,CTNND2,ANKS1B,PHYHIP,PLPPR5,LRRTM3,DNAJC6,BDNF-AS,PTHLH,CADM2,PRDM2,CEP170,CSDE1,KCNJ10,KCNK2,NAV2,DLG2,NKAIN1,PID1,SLC17A6,DSCAM,DTNA,PAK5,JMJD1C,ATL1,RBM12,ABI2" MicroRNA hsa-miR-3158:mirSVR_lowEffct hsa-miR-3158:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.70E-31 3.63E-27 6.09E-30 5.59E-29 86 1480 "SYT9,SYNDIG1,MEG3,RTKN,ADD3,FABP7,CHST15,GPR158,ERICH3,PKP4,APBA2,LRRC55,CGREF1,NAXD,ASPH,SLN,SORCS3,MEGF11,USP33,AHCYL1,JPH4,B4GALNT1,SALL3,NASP,BCL2L2,SEPT3,ARHGEF7,VAMP1,ROBO3,LRIT2,CACNB2,PTBP2,AKNA,USP2,NEURL1,CDK11B,PDE3B,LINC01102,PLEKHB1,GDAP1L1,NRXN2,NEGR1,NMT2,ST8SIA5,FLRT1,MICAL1,FAT3,MED1,SNCAIP,PPP3CB,RGS6,FEZ1,CHD5,NCAN,FMN2,PLPP4,MASP1,WBP1L,ZNF385B,SIRPA,BDNF-AS,PRDM2,SHD,RGMA,CEP170,BLOC1S6,OCIAD1,KCNA6,SMG7,SRGAP3,TMCC2,NAV2,DLG2,NKAIN1,WIPF2,SLC25A48,SLC17A6,RALGDS,SLC25A18,RFX4,INSYN2,PHC2,SYT15,RPRD1A,ABI2,SEZ6" MicroRNA hsa-miR-767-5p:mirSVR_lowEffct hsa-miR-767-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.78E-31 3.67E-27 6.16E-30 5.65E-29 88 1549 "ABAT,ZFYVE27,ACHE,CDHR1,KCNIP2,ADCY2,CDC7,SORCS1,GRAMD1B,TOMM40L,ASIC4,ANK3,PPM1E,DOCK10,AQP4,RUFY2,BRINP2,PHYHIPL,WDTC1,ZSWIM8,ADAM15,KIF1B,SPART,NCAM1,CLASP2,BCL2L2,ZNF302,ADHFE1,NEUROD1,GANAB,NFIA,PCDH11X,UNC5D,TBX15,AZIN2,NUDT21,GRIA2,GRIA4,OPCML,CCKBR,TMEM25,INA,ZFP91,KCNK10,CD81,CDH8,DCLK1,HRH3,PCSK2,ANO5,NLGN3,PIK3CD,UBTF,TJP2,FTO,BTF3L4,MFSD4A,VCAN,FMN2,PRKCZ,NOS1AP,DPYSL5,LRRTM3,SIRPA,JAKMIP2,PTHLH,ELMO1,LRP8,COPS7A,MED24,SRGAP3,RABGAP1L,KCNJ10,PCDH15,KCNMA1,NKAIN1,SLC25A48,DTNA,ABCC9,SLC6A15,RFX4,FAM135B,RNF220,SLC39A12,SH3GLB1,LPAR6,YY1AP1,SEZ6" MicroRNA hsa-miR-34c-3p:mirSVR_lowEffct hsa-miR-34c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.10E-31 3.84E-27 6.44E-30 5.91E-29 83 1380 "SDE2,ACER3,LGR4,SYNDIG1,WLS,KLHL32,GALNT13,NLGN4X,LRRTM4,KIAA1109,FOXG1,SOX6,SGIP1,CDC42BPA,PPFIA1,GPAM,ZCCHC17,CACHD1,API5,MADD,SLC8A3,PDE8B,DNAH17,ATM,PALLD,DKK3,KIF21B,ARPP21,ADGRB2,LMO3,NDUFA5,NEUROD1,NFIA,GLS,PCDH11X,ZNF638,CAMTA1,ANO4,PRUNE2,FAM69C,VSTM2A,AIFM1,TMEM257,KCNK10,CDC42,C1orf94,PCDH9,DCLK1,PCSK2,MAGI1,HMGB1,HPSE2,HNRNPK,TMEFF2,CCSER2,SLC25A27,MFSD4A,ETNPPL,PPP2R5C,MICAL2,FMN2,PLPP4,PKN2,FGFR1OP2,TOX,DNAJC6,PLPPR1,PTHLH,PTPRD,PTPRE,C1orf109,PCDH15,DLG2,PLEKHB2,C12orf4,RASGRF1,BSDC1,ABCC9,ZYG11B,ZNF248,SYT15,SLC4A10,EN2" MicroRNA hsa-miR-4256:mirSVR_lowEffct hsa-miR-4256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.41E-31 4.01E-27 6.71E-30 6.16E-29 80 1282 "MBP,MDM4,CSMD3,KLHL32,SORCS1,BCAR3,CDC42BPA,CNIH2,ITSN1,DGKZ,BCAS1,ZNF365,SLC8A3,SLC14A1,DLL3,ASPH,USP33,B3GALT2,TNIK,B4GALNT1,ARPP21,EMC1,NEK6,KIF1B,COLGALT2,ALDH1L1,HEPN1,RND1,ABCC8,CASTOR3,ZNF638,GNG4,NODAL,BTRC,TBX15,GRIA2,GPR88,OPCML,INA,PAH,DAAM2,CDC42,PDE1A,IGFN1,LINC01102,ZMYND8,PFKFB3,TUB,CHRNB2,ARHGAP22,CADM1,SEMA5B,PIK3CD,FAM181B,NSD2,FEZ1,RIMS4,FMN2,PKN2,USP54,EDRF1,ECE2,WBP1L,SYNC,CA10,PLPPR1,KCNA6,PTPRE,NTM,KCNK2,DLG3,HS3ST4,SLC25A41,DTNA,RGS7,INSYN2,PHC2,ZNF248,TMEM100,EPB41" MicroRNA hsa-miR-1286:mirSVR_lowEffct hsa-miR-1286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.52E-31 4.07E-27 6.80E-30 6.24E-29 89 1586 "TTYH1,ZFYVE27,MEG3,CSMD2,SLC25A25,HOGA1,SCNN1D,KIAA1109,LRRC7,GOLGA7B,TRIM46,SELL,PI16,APBB1,GAS7,CCDC80,ST3GAL3,CLSTN1,USP16,AQP4,SLC1A7,ARFGAP2,CCDC88A,GPR153,SPHKAP,WDTC1,ZCCHC24,LHFPL4,ADAM15,BCL2L2,NDUFA5,SMOC1,ADGRL3,ANO4,ZEB1,DIRAS1,AZIN2,CAMK2A,TMEM151B,BRSK2,AKNA,GRIK3,TMEM9,GUCY1A1,TJP1,CDC42,PADI2,CDH8,ARHGAP19,ZMYND8,ACOT7,TMPRSS5,PFKFB3,CASC2,HPCA,SERPINE2,KIAA1549L,CAMKV,PLXNB3,CNTN1,C11orf49,IFFO1,CNRIP1,MICAL2,PLPP4,CTNND2,NOS1AP,MASP1,WBP1L,JAKMIP2,PMEPA1,PTHLH,PTPRE,KCNH1,RABGAP1L,PCDH15,DLG2,CAB39L,WIPF2,DNM2,PLEKHB2,FAM66C,RALGDS,SUSD4,DSCAM,RASGRF1,DBX2,BSDC1,RNF220" MicroRNA hsa-miR-379*:mirSVR_highEffct hsa-miR-379*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.53E-31 4.08E-27 6.80E-30 6.24E-29 81 1315 "ACER3,IL17D,ERMN,CHST15,HOGA1,SCN3A,LINC00461,KIAA1109,ELMOD1,ITSN1,GPAM,DGKD,NLGN1,BCAS1,CLSTN1,MIER1,BCO1,RUFY2,SHANK2,DACH2,SLCO1A2,SPHKAP,CAPRIN2,ASPH,TMEM108,PHYHIPL,CAB39,ENKUR,PHLDB1,GLS,ZNF638,CAMTA1,TMEM136,ANO4,CACNB2,TCF7L2,ZEB1,CLEC9A,GRM3,TJP1,TLL2,CDC42,TPM4,MAGI1,HMGB1,CADM1,NRXN1,SLC25A27,ACBD5,CRLS1,KCNT2,FEZ1,ATRNL1,DZIP3,CTNND1,ANKS1B,TOMM20,PLPPR5,LRRTM3,PSMD13,BDNF-AS,CADM2,PRDM2,HP1BP3,RGMA,CEP170,OCIAD1,PTPRD,C1orf109,RABGAP1L,KCNK1,PID1,GOPC,ABCC9,SLC6A15,JMJD1C,ARHGEF10L,SEC61A2,SSPN,RAVER2,EN2" MicroRNA hsa-miR-4253:mirSVR_lowEffct hsa-miR-4253:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.13E-31 4.40E-27 7.32E-30 6.72E-29 85 1450 "MAG,SDE2,ATAT1,CSMD2,WLS,GALNT13,SORCS1,SNX32,PLA2G6,ASIC4,GOLGA7B,SLC30A10,FOXG1,MOG,TRIM46,ANK3,PAAF1,USP16,MSR1,SLC6A9,SLC8A3,SPHKAP,LGI3,NAXD,ASTN1,RCOR3,ATM,NRG3,ATP1A3,USP33,KIF21B,SOX10,LHFPL4,ADAM15,COLGALT2,BCL2L2,ADHFE1,NHLH1,DCLK2,WSCD1,GPM6B,TJP1,AIFM1,DAAM2,BEST3,ASIC3,HPCA,HEPACAM,CADM1,CPT1C,OPALIN,MEAF6,PRRX1,NECAB2,ACBD5,SNCAIP,NKAIN4,FEZ2,FEZ1,RAB39A,NRSN1,WBP1L,ZNF385B,PTCH1,CA10,PTHLH,ELMO1,CNIH3,PRDM2,PTPRD,KCND3,KCNJ10,KCNK1,NAV2,DLG2,RALGDS,SUSD4,FAM135B,ZNF248,TTLL7,SFXN5,SIDT2,EPB41L2,SEZ6,BAALC" MicroRNA hsa-miR-1299:mirSVR_highEffct hsa-miR-1299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.25E-31 4.47E-27 7.42E-30 6.81E-29 98 1912 "RABEPK,ABAT,MAP6,TMEM74,SYT9,RCSD1,ACTN2,ADGRV1,MDM4,ERMN,GPR158,LRRTM4,PLA2G6,LRRC7,FHL1,BBOX1,ELMOD1,MOBP,ITSN1,APBA2,MAGI3,GPAM,SORBS1,NLGN1,PAAF1,ZNF365,MIER1,SLC2A5,RUFY2,CCDC88A,NAXD,ASPH,SMARCE1,RCOR3,SNAP25,ENKUR,C11orf87,CLASP2,BCL2L2,ALDH1L1,SMOC1,ADHFE1,NEUROD1,ARHGEF7,ZNF638,LUZP2,GNAS,ANO4,GPM6B,CACNB2,TCF7L2,B4GALNT4,TCF12,GRIA2,RFFL,CRB1,TGFBR3,MFSD2A,TMEM257,CDC42,LGI1,TPD52,MAGI1,BEST3,SERPINE2,CCSER2,BEST1,BTF3L4,NSD2,POU3F2,MED1,CRMP1,PTPA,SNCAIP,CTNND1,PUM1,EDRF1,MASP1,TOX,KIAA0513,PLPPR5,LRRTM3,CEP170,CSDE1,C1orf109,KCNJ10,KCNK2,PCDH15,KCNMA1,DNAH9,SLC25A48,FAM66C,ZYG11B,SLC4A10,RPE65,EPB41L2,RCAN2,RASGRP2" MicroRNA hsa-miR-582-5p:PITA hsa-miR-582-5p:PITA_TOP PITA 8.27E-31 4.48E-27 7.43E-30 6.81E-29 54 544 "EPS8,LGR4,NDRG2,WAC,ERMN,SCN4B,LRRC7,FOXG1,SFPQ,SGIP1,ANK1,ITSN1,APC,AQP4,CAPRIN2,B3GAT1,MYT1L,SOX5,CLASP2,ABCC8,PCDH11X,CAMTA1,CAMSAP2,ADGRL3,GOLGB1,TCF12,PSD3,GRID1,CD81,RBFOX2,ADGRG1,HMGB1,NEGR1,CCSER2,VAV2,POU3F2,PRKCZ,MAPK10,PUM1,TOX,TOMM20,LRRTM3,PMEPA1,HP1BP3,KCNA1,SRGAP3,PEX5,DLG2,TMEM255A,RTN4,PAK5,RGS7,VANGL2,ELAVL3" MicroRNA hsa-miR-499-3p:mirSVR_highEffct hsa-miR-499-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.42E-31 4.56E-27 7.55E-30 6.93E-29 79 1252 "EYA1,SLITRK1,WAC,FGF14,SEMA6A,ACTL6B,FHL1,FOXG1,SOX6,DOCK10,NTNG1,CACHD1,MADD,DACH2,CAPRIN2,ASPH,SLN,SNAP25,SON,MYT1L,SOX5,GAD2,ARPP21,EMC1,C11orf87,FAM168A,GLS,ADGRL3,ANO4,LRIT2,CACNB2,TCF7L2,PTBP2,EML4,SYT6,GRM3,OPCML,CCKBR,MFSD2A,CDC42,CDH10,LGI1,TPM3,TPM4,PCSK2,MAGI1,ANO5,HNRNPK,TMEFF2,NEGR1,PACSIN1,FAAP20,CNRIP1,SNCAIP,ATRNL1,EDRF1,PROX1,DNAJC6,PLPPR1,BDNF-AS,PTHLH,LRP8,PTPRD,KCNA6,C1orf109,NTM,RABGAP1L,KCNMA1,TMEM255A,SLC17A6,PLEKHB2,DPP6,SLC25A18,FAM13C,RFX4,JMJD1C,FGFBP3,CBLN2,UEVLD" MicroRNA hsa-miR-367-3p:TargetScan hsa-miR-367-3p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-32-5p:TargetScan hsa-miR-32-5p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-25-3p:TargetScan hsa-miR-25-3p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-92a-3p:TargetScan hsa-miR-92a-3p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-363-3p:TargetScan hsa-miR-363-3p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-92b-3p:TargetScan hsa-miR-92b-3p TargetScan 9.67E-31 5.24E-27 8.58E-30 7.87E-29 63 776 "EPS8,CEND1,CSMD3,DSCAML1,GRAMD1B,GPR158,KIAA1109,FOXG1,CDC42BPA,ANK3,ASPH,ASTN1,PALLD,DKK3,MYT1L,B3GALT2,AHCYL1,KIF1B,CPLX2,NPAS3,C11orf87,RGL1,NFIA,PCDH11X,DCLK2,DDHD2,ANO4,GPM6A,DIRAS1,CAMK2A,GRIA1,GRIK3,AIFM1,KCNK10,CDC42,RBFOX2,PDE3B,SCRG1,CHGA,KIAA1549L,NOMO2,NEGR1,CCSER2,RBPJ,PRKAB2,SDC3,FMN2,MAPK8,PROX1,ITGAV,PMEPA1,CADM2,KCNA1,PTPRD,KCNH1,RABGAP1L,KCNN3,CALN1,PLEKHB2,BSDC1,INSYN2,ABI2,EN2" MicroRNA hsa-miR-199b-5p:mirSVR_lowEffct hsa-miR-199b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-30 5.65E-27 9.24E-30 8.48E-29 96 1844 "TTYH1,ACHE,ACLY,SYT9,FAM43B,LDLRAD3,CSMD3,ERMN,FCGR1A,TOMM40L,HOGA1,SCN3A,SEMA6A,ASIC4,ANK2,SLC2A5,DACH2,CADPS,SCMH1,NAXD,ASPH,SLN,BRINP2,NRG3,PALLD,SOX5,GAD2,ARPP21,TTLL9,ADAM15,ADGRB2,NAP1L2,BCL2L2,ALDH1L1,STOX1,NEUROD1,GANAB,MLC1,ARHGEF7,GNAS,MYRF,BTRC,KLHL4,CACNB2,PTBP2,NUDT21,TMEM151B,VSTM2A,GRID1,ATP13A2,OMG,CCKBR,LINC00839,TMEM9,HPS5,TNR,CDH8,CHRNB2,SERPINE2,CADM1,NEGR1,A2ML1,SULT4A1,NSD2,PNKD,TENM4,NRSN1,PUM1,GON4L,PTHLH,PRDM2,RGMA,ZC3H11A,OLFM3,PTPRD,PTPRE,PLPPR4,KCNC1,SRGAP3,ARNT2,DNAH9,TMEM255A,SLC17A6,FAM66C,DPP6,RASGRF1,GNE,DBX2,BSDC1,NUP214,RFX4,JMJD1C,ELAVL4,TMEM100,EPB41L1,UEVLD" MicroRNA hsa-miR-580:mirSVR_highEffct hsa-miR-580:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-30 5.78E-27 9.44E-30 8.66E-29 95 1808 "MAG,SERPINA3,ABAT,CDHR1,TMEM74,ATAT1,ARID1A,ADAR,RYR1,ERMN,SLC44A5,GPR158,LRRTM4,LINC00461,LRRC7,FGF14,SLC30A10,MOBP,CNIH2,PPFIA1,TACC2,CACHD1,NLGN1,AQP4,ZNF365,SLC1A6,MSR1,SPHKAP,TMEM108,DKK3,SOX5,ENKUR,ARPP21,NPAS3,SPART,NFASC,NCAM1,CLASP2,RGL1,ADHFE1,ARHGEF7,PCDH11X,CAMSAP2,UNC5D,BTRC,ADGRL3,ANO4,PRUNE2,CACNA1E,NPPA,TCF7L2,ZEB1,EML4,AKNA,GPR88,TMEM257,CDC42,C1orf94,LGI1,PDE1A,PDE4B,BEST3,TMEFF2,CADM1,ANLN,MEAF6,NSD2,ACBD5,MFSD4A,MED1,PPP2R5C,KCNT2,ATRNL1,FMN2,RAB39A,NRSN1,PUM1,MASP1,LRRTM3,ITGAV,PRTFDC1,PTPRD,RABGAP1L,NKAIN1,ABI1,GOPC,SLC6A15,ZYG11B,TTLL7,SYT15,SEC61A2,SLC4A10,EPB41,EPB41L2,UEVLD" MicroRNA hsa-miR-152:mirSVR_highEffct hsa-miR-152:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.11E-30 6.01E-27 9.81E-30 9.00E-29 77 1193 "PRR5L,RTN3,FAM43B,F3,FCGR1A,LRRTM4,KIAA1109,FGF14,APBB1,NTNG1,CCDC80,MIER1,SLC1A7,RUFY2,YPEL4,SPHKAP,ASPH,ATP1A2,DKK3,USP33,SOX5,ENKUR,DNER,SMOC1,NCDN,RGL1,NEUROD1,SYT4,DDHD2,UNC5D,GPM6A,ZEB1,TCF12,SYT6,GRIA1,CCKBR,PAH,TNFRSF1B,HPS5,TNS1,MAGI1,PDE1A,PDE1C,PDYN,CHI3L2,GDAP1L1,CADM1,UBTF,P2RY12,CNRIP1,POU3F2,CHD1L,PTPA,FEZ2,ATRNL1,RAB39A,PRKCZ,IGSF1,CTNND1,MAPK10,SPIRE1,SYNC,CA10,PTHLH,CADM2,PTPRD,NTM,KCNN3,DLG2,DLG3,TMEM255A,DNM2,RALGDS,C12orf4,SLC25A18,RTN4,C2orf80" MicroRNA hsa-miR-302f:mirSVR_highEffct hsa-miR-302f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-30 6.15E-27 1.00E-29 9.19E-29 72 1038 "LGR4,ACTN2,CSMD2,DSCAML1,SLITRK1,ADD3,SORCS1,CHST15,LRRTM4,LINC00461,SGIP1,ANK3,PPFIA1,PKP4,DOCK10,NLGN1,MSR1,SHANK2,CAPRIN2,ASPH,SMARCE1,RCOR3,ATP2B2,SOX5,MYH7,NPAS3,RAP1GAP2,NDUFA5,NEUROD1,SEPT3,AJAP1,SYT4,POPDC3,UNC5D,ADGRL3,TMEM136,PRUNE2,GPM6B,TCF7L2,PTBP2,GRIA1,CRB1,LEFTY2,BEST3,TJP2,ST8SIA5,SPATA6,P2RY12,CRLS1,KCNT2,FEZ1,ATRNL1,CTNND1,NRSN1,FGFR1OP2,SYNC,LRRTM3,PRDM2,MAGI2,PTPRZ1,AK5,CAB39L,PID1,ABI1,GOPC,FAM13C,L1CAM,SLC6A15,RFX4,TTLL7,CBLN2,RPE65" MicroRNA hsa-let-7c*:mirSVR_lowEffct hsa-let-7c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-30 6.41E-27 1.04E-29 9.56E-29 88 1561 "PRR5L,WLS,KLHL32,RTN1,DSCAML1,SLITRK1,FOXRED2,KIAA1109,BCAR3,SOX6,SGIP1,ANXA7,MSR1,ARFGAP2,DACH2,GPR153,CSPG5,SLCO1A2,MTR,TMEM108,ATP2B2,SON,TNIK,NMNAT2,KIF1B,ALDH1L1,STOX1,DCAF5,KIRREL3,NFIA,PCDH11X,ZNF638,DCLK2,TMEM136,PRUNE2,LRIT2,PRLHR,TCF7L2,ZEB1,NUDT21,PSD3,CRB1,TJP1,MAEL,REPS2,PADI2,PCDH9,ARHGAP19,TPD52,PDE1A,ZMYND8,ANO5,ASIC3,CASC2,JAM2,NRXN1,SEMA5B,CCSER2,CNTN1,CELF5,CNRIP1,CRLS1,PPP2R5C,PRKAB2,FAM131B,PROX1,MASP1,SPIRE1,SYNC,SIRPA,PLPPR1,CADM2,PRDM2,LRP8,BLOC1S6,RABGAP1L,KCNJ10,PCDH15,SNX27,KLRC2,SLC17A6,GNE,DTNA,ZYG11B,PHC2,RERGL,RPE65,BAALC" MicroRNA hsa-miR-21:mirSVR_lowEffct hsa-miR-21:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-30 6.48E-27 1.05E-29 9.65E-29 85 1458 "ACLY,MBP,SORCS1,SNX30,FCGR1A,GPR158,FOXG1,MOG,SOX6,FOXM1,USP28,PKP4,PPM1E,GPAM,NLGN1,MSR1,LRRC55,DACH2,ASCL1,CSPG5,ASPH,SMARCE1,TMEM108,TTLL9,NPAS3,NCAM1,LMO3,DCAF5,PHLDB1,NFIA,PCDH11X,ZNF638,DDHD2,CNTN2,TMEM136,ANO4,CACNA1E,NUMA1,OLR1,CRB1,TGFBR3,TMEM9,ZFP91,KCNK10,HPS5,PCDH8,LGI1,PCSK2,ACOT7,ZFYVE9,CCSER2,ACBD5,CHD1L,RNF14,PRKAB2,SDC3,FMN2,PKN2,USP54,NRSN1,EDRF1,NOS1AP,KIAA0408,CADM2,HP1BP3,SHD,CDH20,OCIAD1,SMG7,SV2A,KCNJ10,KCNK1,KCNK2,PCDH15,DLG2,PID1,FAM66C,BSDC1,RET,JMJD1C,RGS10,FAM135B,ATL1,SEC61A2,VWA5A" MicroRNA hsa-miR-197:mirSVR_lowEffct hsa-miR-197:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-30 6.68E-27 1.08E-29 9.93E-29 90 1632 "RABEPK,SERPINA3,MAPT,CDHR1,LGR4,RCSD1,SYNDIG1,IL17D,MDM4,F3,ADORA3,TOMM40L,SEMA6A,MOBP,CDC42BPA,ANK2,ANK3,CNIH2,PPM1E,NTNG1,DGKZ,SORBS1,PAAF1,LRRC55,SLC8A3,MT3,NSG2,DACH2,SORCS3,EIF4G3,SON,TNIK,GAD2,EMC1,NEK6,FXYD6,NPAS3,GFAP,DCLK2,DDHD2,NODAL,MMD2,TMEM136,GPM6B,ACSL6,TCF12,AZIN2,NUDT21,NUMA1,ADAMTS8,CYB561A3,SPX,TJP1,ZDHHC22,PADI2,CDH8,ARHGAP19,FNDC5,CHGA,PFKFB3,TMEFF2,JAM2,CAMKV,A2ML1,SULT4A1,P2RY12,MFSD4A,CHD1L,PPP3CB,FEZ2,DZIP3,TOMM20,LRRTM3,PTCH1,ITGAV,BDNF-AS,PRDM2,RGMA,SMG7,SV2A,SRGAP3,KCNJ9,KCNK2,KCNMA1,DNAH9,ATN1,GOPC,ZYG11B,RFX4,LPAR6" MicroRNA hsa-miR-452:mirSVR_highEffct hsa-miR-452:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-30 6.99E-27 1.13E-29 1.04E-28 93 1740 "EPS8,MAP6,SYNDIG1,ACTN2,ADGRV1,IL17D,LDLRAD3,CSMD3,ADD3,FABP7,NLGN4X,SLC44A5,LINC00461,LRRC7,SEMA6A,ANK2,USP28,PPFIA1,SH3GL2,API5,CLSTN1,PKNOX2,SLC8A3,CCDC88A,DACH2,ASCL1,SMARCE1,RCOR3,PHYHIPL,DKK3,SON,MYT1L,B3GALT2,CAB39,SALL3,SPART,ERBIN,GLS,PCDH11X,KLHL4,GPM6A,CACNA1E,ZEB1,CAMK2G,GRIA4,GRM3,TLL2,MAEL,CDC42,IGSF21,SERPINE2,CADM1,ZFYVE9,CCSER2,FAM181B,CNTN1,BTF3L4,MED1,PPP2R5C,PPP3CB,RBPJ,FMN2,PKN2,USP54,FGFR1OP2,SYTL2,ANKS1B,ZNF385B,PTHLH,CADM2,HP1BP3,NTM,RABGAP1L,KCNK2,PID1,TMEM255A,SLC17A6,FAM66C,ABI1,FAM13C,DTNA,SLC6A15,ZYG11B,NUP214,ZNF248,SEC61A2,RNF220,VWA5A,FGFBP3,ARHGAP12,SLC4A10,ELAVL4,EPB41L1" MicroRNA hsa-miR-28-3p:mirSVR_lowEffct hsa-miR-28-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-30 7.08E-27 1.14E-29 1.05E-28 78 1228 "EPS8,SYT9,CLIP1,ADCY2,GALNT13,AMER2,LINC00461,UNC79,SOX6,ASRGL1,ITSN1,ANXA7,DOCK10,SESN3,MAGI3,SORBS1,LRRC4C,AQP4,SLC7A14,SHANK2,ASPH,RCOR3,ATM,ATP1A2,WDTC1,CAB39,NMNAT2,ENKUR,EMC1,C11orf87,SEPT3,VAMP1,PCDH11X,DDHD2,UNC5D,ADGRL3,PRLHR,ZEB1,NUDT21,SYT6,CRB1,TJP1,PAX6,TPM4,PDE1A,PIRT,BEST3,SCRG1,TUB,TMEFF2,NEGR1,CCSER2,ACBD5,POU3F4,PPP2R5C,CSF3R,OSBPL3,PRKAB2,PRKACB,FMN2,CTNND2,ZBTB16,SPIRE1,PLPPR5,DNAJC6,CADM2,MAGI2,BLOC1S6,PLPPR4,PTPRZ1,KCNJ9,ARNT2,KCNMA1,NAV2,PLEKHB2,ABCC9,SSPN,VWA5A" MicroRNA hsa-miR-1265:mirSVR_lowEffct hsa-miR-1265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-30 7.27E-27 1.17E-29 1.07E-28 92 1705 "RABEPK,ASIC1,CNTNAP3,SYT9,ADGRV1,KLHL32,WAC,SORCS1,GRAMD1B,ADORA3,FCGR1B,LRRC7,MOBP,TRIM46,ERICH3,DOCK10,ST8SIA1,SFMBT2,SLC2A5,MSR1,LRRC55,SCMH1,DLL3,ASPH,SMARCE1,ADGRA1,SNAP25,MEGF11,SOX5,KIF21B,ZSWIM8,AHCYL1,TTLL9,SPART,NFASC,CLASP2,COLGALT2,ALDH1L1,SEPT3,GLS,GNG4,NODAL,BTRC,CNTN2,KLHL4,WSCD1,LILRA1,PCDHGA3,ATP13A2,CRB1,P2RX7,GUCY1A1,DAAM2,PAX6,CDC42,TNR,CDH8,ARHGAP19,LGI1,PDE1C,PDE2A,CHGA,ASIC3,CASC2,NLGN3,SEMA5B,ST8SIA5,CNTN1,PMP2,BEST1,NXPH1,SNCAIP,PRKAB2,MAPK10,WBP1L,PSMD13,SIRPA,ELMO1,STMN4,SRGAP3,KCNMA1,PEX5,SLC25A48,SLC17A6,RALGDS,GOPC,DTNA,RET,INSYN2,ZNF248,SYT15,EPB41L2" MicroRNA hsa-miR-455-3p:mirSVR_lowEffct hsa-miR-455-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-30 7.27E-27 1.17E-29 1.07E-28 92 1705 "RABEPK,TTYH1,LDLRAD3,MDM4,SLC25A25,CSMD3,SNX30,TESK2,LRRTM4,SEMA6A,GOLGA7B,MOBP,ANK3,APBA2,GPAM,SORBS1,STK32C,ZNF365,SLC7A14,SHANK2,PDE8B,SMARCE1,B3GAT1,TMEM108,EIF4G3,ILDR2,TTLL9,ADAM15,FXYD6,COLGALT2,BCL2L2,ALDH1L1,STOX1,GFAP,ARHGEF7,LUZP2,GNAS,CACNB2,LILRA1,PTBP2,NUDT21,CAMK2A,PCDHGA3,NUMA1,PSD3,GRIA4,ADAMTS8,GRM3,CCKBR,CRB1,MFSD2A,REPS2,PCDH9,PRMT8,PIRT,ZMYND8,HMGB1,ASIC3,JAM2,KIAA1549L,NRXN1,NEGR1,CNTN1,BTF3L4,PRRX1,ETNPPL,PPP2R5C,TENM4,PPP3CB,NKAIN4,FEZ1,MICAL2,PRKAB2,PRKCG,ZBTB16,PLPPR5,PLPPR1,PTHLH,OCIAD1,PTPRD,SMG7,KCNJ9,KCNK2,CAB39L,DNAH9,RASGRF1,ZYG11B,RGS10,SEC61A2,RBM12,ELAVL4,RPE65" MicroRNA hsa-miR-532-5p:mirSVR_lowEffct hsa-miR-532-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-30 7.59E-27 1.22E-29 1.12E-28 92 1706 "ACER3,TMEM74,MBP,RTN1,SLITRK1,NLGN4X,MOG,SOX6,ANK2,ITSN1,PPM1E,CCDC80,SHTN1,AQP4,MIER1,ARHGAP5,NSG2,SCG3,ASPH,DDX25,NRG3,MEGF11,WDTC1,B3GALT2,ARPP21,TTLL9,IDI2-AS1,KIF1B,COLGALT2,STOX1,ADHFE1,GLS,SYT4,POPDC3,LUZP2,KAZN,DDHD2,UNC5D,BTRC,CNTN2,KLHL4,CACNA1A,TCF7L2,PTBP2,CECR2,NUMA1,AKNA,GRIA4,GRID1,LINC00839,KCNK10,MAEL,TNFRSF1B,TPD52,TPM3,MAGI1,PDE1C,PDE2A,FNDC5,BEST3,LRTM2,FLRT1,PRRX1,CNRIP1,PPP2R5C,RGS6,DZIP3,RAB39A,PRKCG,KIAA0408,MASP1,TOX,WBP1L,ANKS1B,DNAJC6,PLPPR1,COPS7A,STMN4,KCNJ9,KCNK2,KCNMA1,RAB3IL1,TMEM255A,DNM2,PLEKHB2,RALGDS,DTNA,ZYG11B,ARHGEF10L,TTLL7,SFXN5,SSPN" MicroRNA hsa-miR-4319:mirSVR_lowEffct hsa-miR-4319:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-30 7.72E-27 1.24E-29 1.14E-28 83 1394 "ABAT,MAP6,ACHE,EMID1,MEG3,FAM43B,PLEKHG5,ERMN,FCGR1A,SNX32,ASIC4,MOBP,PI16,ITSN1,PKP4,APC,MAGI3,DGKZ,API5,ARFGAP2,DACH2,GPR153,LGI3,C10orf105,NRG3,WDTC1,ENKUR,B4GALNT1,NFASC,ADHFE1,SEPT3,GLS,ZNF638,GNAS,TMEM136,CACNA1E,DDR1,DIRAS1,CECR2,GRIA2,TF,CRB1,PADI2,CDH8,PTGDR2,HRH3,PDE3B,CASC2,KIAA1549L,NRXN1,CAMKV,OPALIN,FADS2,MFSD4A,POU3F2,PTPA,PPP2R5C,TENM4,NCAN,PRKCZ,MAPK10,FAM131B,ECE2,PROX1,PSMD13,PRDM2,CSDE1,ZC3H11A,KCNA1,PTPRE,C1orf109,PCDH15,CAB39L,WIPF2,PARP11,GOPC,DTNA,ZYG11B,RET,FAM135B,PHC2,ZNF248,SYT15" MicroRNA hsa-miR-520d-3p:mirSVR_highEffct hsa-miR-520d-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.97E-30 1.07E-26 1.71E-29 1.57E-28 82 1367 "EPS8,LGR4,MDM4,AMER2,GPR158,SGIP1,ANK2,MAGI3,SLITRK3,TACC2,API5,CLSTN1,USP16,SLC1A6,SLC14A1,ASPH,RCOR3,MEGF11,MYT1L,TNIK,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,GPM6A,CACNA1E,TCF7L2,ZEB1,SYT6,VSTM2A,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,TNFRSF1B,HPS5,TNS1,C1orf94,PCDH9,MAGI1,PRMT8,FAM181B,BTF3L4,PRRX1,SPATA6,ACBD5,CNRIP1,MED1,PPP3CB,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,PLPPR5,SYNC,ITGAV,PTHLH,CADM2,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRD,KCNMA1,HS3ST4,SLC17A6,FAM13C,DTNA,PAK5,SLC6A15,TMEM100" MicroRNA hsa-miR-196b:mirSVR_lowEffct hsa-miR-196b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-30 1.09E-26 1.74E-29 1.59E-28 78 1236 "RABEPK,ZFYVE27,ACER3,CNTNAP3,LGR4,WLS,CLIP1,GALNT13,SLC44A5,CHST15,ELMOD1,AMPH,AQP4,ARFGAP2,ASCL1,SLCO1A2,TMEM108,TNIK,ARPP21,TTLL9,LMO3,NDUFA5,STOX1,NCDN,ADHFE1,ACSBG1,PRUNE2,AZIN2,AKNA,RFFL,ADAMTS8,CCKBR,CRB1,TGFBR3,MAEL,PCDH8,PDE2A,ADGRG1,HMGB1,PFKFB3,ASIC3,TUB,CCSER2,DNAJC12,FLRT1,CELF5,NSD2,MFSD4A,ETNPPL,RGS6,KCNT2,FMN2,PRKCZ,CTNND2,NRSN1,MASP1,PLPPR5,LRRTM3,ITGAV,BDNF-AS,PRDM2,COPS7A,CSDE1,BLOC1S6,KCNA1,PCDH15,DLG2,PARP11,DSCAM,DTNA,BSDC1,ZYG11B,RET,RFX4,FAM135B,ABI2,EPB41,UEVLD" MicroRNA hsa-miR-944:PITA hsa-miR-944:PITA_TOP PITA 2.08E-30 1.13E-26 1.80E-29 1.65E-28 69 958 "LGR4,EYA1,CLIP1,KLHL32,RTN1,ERMN,GPR158,KIAA1109,SEMA6A,BCAR3,SOX6,ERICH3,ANK3,APC,GPAM,SORBS1,NLGN1,SHTN1,ARHGAP5,SLC8A3,CCDC88A,SORCS3,ASTN1,PHYHIPL,ATP2B2,PALLD,NPAS3,BCL2L2,ERBIN,NEUROD1,DCLK2,CAMSAP2,CAMK2G,CECR2,GRIA2,GRIA4,OPCML,TLL2,TMEM257,DCLK1,PCSK2,MAGI1,HMGB1,HPCA,NEGR1,PMP2,PRRX1,FAT3,KCNT2,PRKAB2,DZIP3,PKN2,PTCH1,ITGAV,LRP8,ZC3H11A,PTPRO,KCNK2,DLG2,ATN1,SLC6A15,ST8SIA3,JMJD1C,SSPN,GPR61,SLC4A10,ELAVL3,EN2,EPB41L1" MicroRNA hsa-miR-646:mirSVR_highEffct hsa-miR-646:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-30 1.17E-26 1.87E-29 1.72E-28 65 843 "ATAT1,MDM4,CDC7,SLC44A5,HOGA1,PPFIA1,ITSN1,CCDC80,CACHD1,DACH2,SNCB,CCDC181,GABBR1,MYT1L,SOX5,ZSWIM8,AHCYL1,SALL3,DNER,NPAS3,KIRREL3,NEUROD1,GANAB,FAM168A,ACSBG1,ZNF638,GNAS,CAMTA1,CAMSAP2,ZEB1,SYT6,GPR88,OLR1,CRB1,SPX,AIFM1,TPM3,ACOT7,CADM1,ANLN,CNTN1,PMP2,BEST1,BTF3L4,NXPH1,ACBD5,PPP2R5C,PPP3CB,ATRNL1,RBPJ,DZIP3,PKN2,CTNND1,ZC3H11A,AK5,DLG3,KIF2A,RTN4,ABCC9,INSYN2,SEC61A2,YY1AP1,C2orf80,TMEM100,RCAN2" MicroRNA hsa-miR-424-5p:TargetScan hsa-miR-424-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-15b-5p:TargetScan hsa-miR-15b-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-195-5p:TargetScan hsa-miR-195-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-16-5p:TargetScan hsa-miR-16-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-15a-5p:TargetScan hsa-miR-15a-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-497-5p:TargetScan hsa-miR-497-5p TargetScan 2.23E-30 1.21E-26 1.90E-29 1.75E-28 73 1080 "EYA1,GALNT13,SCN3A,SCN4B,FGF1,ELMOD1,HPCAL4,CNIH2,PPM1E,APC,NLGN1,ARHGAP5,ARFGAP2,GPR153,RCOR3,ATP2B2,GABBR1,MYT1L,CAB39,NMNAT2,ARPP21,SALL3,LHFPL4,KIF1B,NPAS3,NFASC,COLGALT2,BCL2L2,DCAF5,ACSBG1,OS9,BTRC,CACNA1E,DDR1,RFFL,GRIN1,OMG,AIFM1,KCNK10,PDE3B,HPSE2,CADM1,CAMKV,ANLN,FAT3,NXPH1,POU3F2,MED1,RNF14,PPP2R5C,CHD5,RBPJ,PRKAB2,MAPK8,KIAA0513,RIMS3,PTCH1,PTHLH,CNIH3,RGMA,CSDE1,PTPRD,PEX5,PID1,FAM57B,RTN4,BSDC1,RET,JMJD1C,RBM12,ABI2,EN2,EPB41L1" MicroRNA hsa-miR-29b-2*:mirSVR_highEffct hsa-miR-29b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-30 1.21E-26 1.91E-29 1.76E-28 84 1437 "SDE2,TMEM74,SYT9,WLS,RTKN,ADARB2,FCGR1A,LRRC7,UNC79,SGIP1,PPFIA1,ITSN1,MAGI3,NLGN1,AQP4,SCMH1,C10orf105,NRG3,PHYHIPL,ARPP21,DNER,FXYD6,NPAS3,NCAM1,STOX1,ERBIN,NEUROD1,PCDH11X,SYT4,GNAS,DDHD2,ADGRL3,PTBP2,EML4,CECR2,TMEM151B,GRIA4,GRIK2,CCKBR,CRB1,TMEM25,LEFTY2,INA,CDH8,CDH10,TPD52,MAGI1,ZNF384,PRMT8,CASC2,TMEFF2,SERPINE2,ANLN,A2ML1,FAM181B,CNTN1,CP,PPP3CB,KCNT2,ATRNL1,PRKACB,PKN2,ARHGEF4,NRSN1,PROX1,SYNC,PRTFDC1,OLFM3,PTPRO,KCNN3,DNAH9,SLC17A6,RAD52,C12orf4,DSCAM,RASGRF1,SLC6A15,NUP214,USH1C,FAM135B,EFNA3,RBM12,ABI2,ARHGAP12" MicroRNA hsa-miR-449b*:mirSVR_highEffct hsa-miR-449b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-30 1.26E-26 1.98E-29 1.82E-28 65 844 "CDHR1,LGR4,RTN3,CLIP1,ERMN,KIAA1109,PPFIA1,ITSN1,APC,SLITRK3,NSG2,CADPS,SORCS3,TMEM108,SON,ARPP21,TTLL9,DNER,NAP1L2,FXYD6,NCAM1,NEUROD1,PCDH11X,NKX2-2,ADGRL3,KLHL4,CACNA1E,TCF7L2,ZEB1,PTBP2,EML4,CAMK2A,GRIK2,TMEM257,CDH8,LGI1,PDE4B,CAMKV,TJP2,CCDC136,PRRX1,CRMP1,PPP2R5C,PPP3CB,RBPJ,PRKACB,PRKCZ,CTNND1,ZBTB16,PLPPR5,ZNF385B,PSMD13,PLPPR1,PTHLH,LRP8,C1orf109,KCNK2,PCDH15,TMEM255A,ABCC9,RFX5,RGS7,SLC4A10,EN2,RPE65" MicroRNA hsa-miR-181d:PITA hsa-miR-181d:PITA_TOP PITA 2.33E-30 1.26E-26 1.98E-29 1.82E-28 64 816 "EPS8,MAPT,SLC25A25,CLIP1,SLITRK1,ERMN,SOX6,CDC42BPA,ANK1,ITSN1,DOCK10,API5,MADD,PKNOX2,CAPRIN2,SNAP25,ATP2B2,PALLD,MEGF11,SOX5,NMNAT2,LMO3,DCAF5,SEPT3,UNC5D,PTBP2,CAMK2G,CECR2,PSD3,GRIA2,GRIK2,GPR88,KCNK10,TNS1,DCLK1,PDE3B,KIAA1549L,NRXN1,NEGR1,NMT2,CCSER2,FAT3,POU3F2,SF1,TENM4,OSBPL3,ATRNL1,DOCK7,PUM1,PROX1,TOX,BLOC1S6,ZC3H11A,PTPRE,ARNT2,KCNMA1,DPP6,ABI1,PAK5,ST8SIA3,TTLL7,LMO1,SLC4A10,EN2" MicroRNA hsa-miR-181b:PITA hsa-miR-181b:PITA_TOP PITA 2.33E-30 1.26E-26 1.98E-29 1.82E-28 64 816 "EPS8,MAPT,SLC25A25,CLIP1,SLITRK1,ERMN,SOX6,CDC42BPA,ANK1,ITSN1,DOCK10,API5,MADD,PKNOX2,CAPRIN2,SNAP25,ATP2B2,PALLD,MEGF11,SOX5,NMNAT2,LMO3,DCAF5,SEPT3,UNC5D,PTBP2,CAMK2G,CECR2,PSD3,GRIA2,GRIK2,GPR88,KCNK10,TNS1,DCLK1,PDE3B,KIAA1549L,NRXN1,NEGR1,NMT2,CCSER2,FAT3,POU3F2,SF1,TENM4,OSBPL3,ATRNL1,DOCK7,PUM1,PROX1,TOX,BLOC1S6,ZC3H11A,PTPRE,ARNT2,KCNMA1,DPP6,ABI1,PAK5,ST8SIA3,TTLL7,LMO1,SLC4A10,EN2" MicroRNA hsa-miR-135a:mirSVR_highEffct hsa-miR-135a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.35E-30 1.27E-26 2.00E-29 1.83E-28 84 1438 "ABAT,TMEM74,SYT9,EYA1,MRVI1,ATAT1,MDM4,ADAR,GALNT13,FABP7,TMEM156,LRRC7,HPCAL4,SELL,ANK3,ANXA7,PKP4,PPM1E,APC,NTNG1,ST3GAL3,API5,ZNF365,SLC6A9,CCDC88A,PDE8B,SPHKAP,ASPH,SMARCE1,ATP1A2,ZCCHC24,CADM3,CPLX2,NAP1L2,ZNF302,HEPN1,RGL1,ARHGEF7,POPDC3,GNG3,NODAL,CNTN2,TMEM136,KLHL4,ANO4,GPM6B,TCF7L2,TCF12,PTBP2,CAMK2G,GRIA4,CRB1,TMEM9,HPS5,PCDH9,PDE3B,GDAP1L1,ANLN,OPALIN,CNTN1,PRRX1,CRLS1,PPP2R5C,RGS6,MICAL2,ATRNL1,VCAN,FMN2,PKN2,USP54,NRSN1,MASP1,ZNF385B,ITGAV,JAKMIP2,CEP170,STMN4,KCNMA1,CAB39L,RTN4,PAK5,CAMK1G,RFX5,SLC4A10" MicroRNA hsa-let-7g*:mirSVR_highEffct hsa-let-7g*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-30 1.29E-26 2.01E-29 1.85E-28 77 1207 "LGR4,RTN3,MEG3,EYA1,ARID1A,KLHL32,DSCAML1,LRRC7,UNC79,ANK1,CNIH2,ITSN1,SH3GL2,DOCK10,NTNG1,SLITRK3,SORBS1,SYBU,BCAS1,CSPG5,MEGF11,MYT1L,SOX10,SALL3,NEK6,ADGRB2,CLASP2,ZNF302,ERBIN,GFAP,DCAF5,KIRREL3,DDHD2,CAMTA1,NODAL,ADGRL3,GPM6B,TCF7L2,ZEB1,PTBP2,GRIK3,PTPN5,TJP1,PCDH8,CDH10,SEZ6L,TPM3,MAGI1,HMGB1,NLGN3,CAMKV,DNAJC12,FLRT1,NXPH1,PPP2R5C,MICAL2,PLCH2,TOMM20,LRRTM3,ITGAV,CEP170,MAGI2,SMG7,KCNK1,KCNK2,DNAH9,RASGRF1,FAM13C,DTNA,RFX4,JMJD1C,RGS7,ARHGEF10L,VANGL2,VWA5A,ARHGAP12,TMEM100" MicroRNA hsa-miR-597:mirSVR_lowEffct hsa-miR-597:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.59E-30 1.40E-26 2.19E-29 2.01E-28 84 1440 "TTYH1,CDHR1,MBP,WLS,MDM4,ADAR,HOGA1,ANK3,CNIH2,CCDC80,AQP4,RUFY2,NSG2,GPR153,SLCO1A2,SPHKAP,ADGRA1,ALDH4A1,MYT1L,ARPP21,C11orf87,NDUFA5,KAZN,GNG4,MYRF,WWC1,ANO4,PRUNE2,ACSL6,DDR1,HAP1,AZIN2,GRIA1,OPCML,TJP1,TLL2,C1orf94,CDH8,SEZ6L,PDE3B,PRMT8,JAM2,SERPINE2,A2ML1,ST8SIA5,C11orf49,NSD2,CNRIP1,CP,MED1,PPP2R5C,RGS6,KCNT2,NCAN,PRKACB,FMN2,PRKCZ,CTNND2,KIAA0408,BRINP3,KLK6,PLPPR5,PTCH1,BDNF-AS,PTHLH,PRDM2,CEP170,BLOC1S6,PTPRO,RABGAP1L,KCNJ10,ARNT2,KCNK1,PID1,PLEKHB2,FAM13C,SLC6A15,RET,ARHGEF10L,SLC39A12,GPR61,ABI2,RAVER2,PRRT4" MicroRNA hsa-miR-3201:mirSVR_lowEffct hsa-miR-3201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.65E-30 1.43E-26 2.24E-29 2.05E-28 77 1209 "ACER3,MBP,SYT9,WLS,GALNT13,GOLGA7B,MOG,PPFIA1,MAGI3,CACHD1,NLGN1,PAAF1,YPEL4,CCDC88A,GPR153,SPHKAP,DLL3,SORCS3,ASTN1,RCOR3,MYT1L,ARPP21,ADAM15,NFASC,BCL2L2,STOX1,NEUROD1,AJAP1,GLS,RHBDL3,NHLH1,CNTN2,ANO4,GPM6A,CACNA1E,PTBP2,GRIA2,GRIK2,CRB1,PADI2,CDH10,DCLK1,TPM4,PDE2A,CASC2,GDAP1L1,TJP2,NXPH1,MFSD4A,POU3F2,MED1,SNCAIP,ATRNL1,DZIP3,PLPP4,EDRF1,ANKS1B,CADM2,HP1BP3,CSDE1,PTPRD,PLPPR4,SRGAP3,KCNJ10,TMCC2,PCDH15,NAV2,DLG2,KLRC2,PLEKHB2,DPP6,RASGRF1,DBX2,RFX4,EPB41,EPB41L1,UEVLD" MicroRNA hsa-miR-591:mirSVR_lowEffct hsa-miR-591:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.76E-30 1.49E-26 2.33E-29 2.13E-28 78 1242 "MRVI1,WLS,CSMD3,HOGA1,MOBP,TRIM46,ANK2,ITSN1,SH3GL2,DOCK10,SLITRK3,CLSTN1,URGCP,TAGLN3,NAXD,SLN,ATP1A2,ATP2B2,GABBR1,AHCYL1,B4GALNT1,NPAS3,NDUFA5,GPR162,DCAF5,INKA2,NELL1,SLCO1C1,GLS,LUZP2,KAZN,MMD2,TBX15,PRUNE2,LRIT2,PTBP2,CECR2,GRIA2,GRIA4,TJP1,PCSK2,FNDC5,ANO5,TMEFF2,NEGR1,NMT2,SLC25A27,ATCAY,POU3F2,PPP2R5C,SNCAIP,DOCK7,FMN2,PLPP4,PUM1,FGFR1OP2,MASP1,TUBB2B,CA10,PLPPR1,CEP170,OCIAD1,PTPRE,KCNC1,PCDH15,PID1,DNM2,FAM66C,ATN1,DTNA,BSDC1,NUP214,ATL1,ARHGEF10L,ZNF248,RNF220,PIANP,LPAR6" MicroRNA hsa-miR-411*:mirSVR_highEffct hsa-miR-411*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-30 1.51E-26 2.35E-29 2.16E-28 77 1210 "ACER3,IL17D,HOGA1,SCN3A,LINC00461,KIAA1109,ELMOD1,ITSN1,GPAM,NLGN1,BCAS1,CLSTN1,MIER1,BCO1,RUFY2,SHANK2,DACH2,SLCO1A2,SPHKAP,CAPRIN2,ASPH,TMEM108,PHYHIPL,CAB39,ENKUR,LMO3,PHLDB1,GLS,ZNF638,CAMTA1,TMEM136,ANO4,CACNB2,TCF7L2,ZEB1,CLEC9A,GRM3,TJP1,TLL2,CDC42,TPM4,MAGI1,HMGB1,CADM1,NRXN1,SLC25A27,ACBD5,CRLS1,KCNT2,FEZ1,ATRNL1,CTNND1,ANKS1B,TOMM20,PLPPR5,LRRTM3,PSMD13,BDNF-AS,CADM2,PRDM2,HP1BP3,RGMA,CEP170,OCIAD1,PTPRD,C1orf109,RABGAP1L,KCNK1,PID1,GOPC,ABCC9,SLC6A15,JMJD1C,ARHGEF10L,SEC61A2,SSPN,EN2" MicroRNA hsa-miR-1264:mirSVR_highEffct hsa-miR-1264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.18E-30 1.72E-26 2.68E-29 2.46E-28 91 1689 "ACER3,MEG3,ARID1A,MDM4,CSMD3,CLIP1,PLEKHG5,HHATL,CDC7,FABP7,TESK2,KIAA1109,LRRC7,ELMOD1,CDC42BPA,MAGI3,NLGN1,BCAS1,PAAF1,MIER1,RUFY2,MSR1,CAPRIN2,ASPH,RCOR3,ATM,ATP2B2,MEGF11,MYT1L,ARPP21,SPART,COLGALT2,SMOC1,ERBIN,GLS,ZNF638,DCLK2,CAMSAP2,PSRC1,KLHL4,VWC2,TCF7L2,TCF12,CAMK2G,GRIA1,GRIA4,RFFL,GPR88,INA,PCDH9,MAGI1,PDE1A,PDE1C,CASC2,HNRNPK,TMEFF2,ZFYVE9,NRXN1,TJP2,ST8SIA5,CNTN1,SPATA6,NSD2,CNRIP1,MFSD4A,SF1,PPP2R5C,PPP3CB,KCNT2,ATRNL1,NCAN,PRKACB,PKN2,PLD5,TOX,SPIRE1,SYNC,ITGAV,CEP170,OLFM3,PTPRZ1,RABGAP1L,DLG2,FAM13C,DTNA,RTN4,SLC6A15,RFX4,TTLL7,GPR61,ARHGAP12" MicroRNA hsa-miR-182*:mirSVR_lowEffct hsa-miR-182*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.29E-30 1.78E-26 2.76E-29 2.53E-28 76 1181 "DPF1,ABAT,LGR4,DSCAML1,GALNT13,GPR158,FGF1,SEMA6A,BCAR3,FGR,GOLGA7B,PKP4,SESN3,CACHD1,MADD,MSR1,LRRC55,MT3,DACH2,NAXD,BRINP2,TMEM108,CCDC181,PHYHIPL,B3GALT2,EMC1,KIF1B,C11orf87,NEUROD1,ARHGEF7,NHLH1,LUZP2,GPM6B,ZEB1,VSTM2A,AKNA,RFFL,TGFBR3,PADI2,TPD52,TPM3,PDE3B,PRMT8,TUB,OPALIN,TJP2,PMP2,CABP1,BEST1,SPATA6,RNF14,SNCAIP,PRKACB,DOCK7,FMN2,PLD5,CTNND1,CTNND2,EDRF1,ANKS1B,ZNF385B,PLPPR1,MAGI2,SRGAP3,KCNJ10,PCDH15,CAB39L,PID1,RASGRF1,PAK5,ABCC9,RGS7,INSYN2,EFNA3,RBM12,SLC4A10" MicroRNA hsa-miR-496:mirSVR_lowEffct hsa-miR-496:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-30 1.82E-26 2.81E-29 2.58E-28 89 1619 "RABEPK,EPS8,RPL38,LDLRAD3,WLS,SORCS1,TOMM40L,KIAA1109,LRRC7,FGF14,MOBP,SELL,SGIP1,RASA3,CNIH2,DOCK10,SESN3,NTNG1,CCDC80,GPAM,NLGN1,SHTN1,RPH3A,ARHGAP5,CCDC88A,DACH2,SCMH1,ASCL1,GPR153,CSPG5,SLCO1A2,MTR,CCDC181,USP33,TNIK,ENKUR,NPAS3,LMO3,C11orf87,ADHFE1,PCDH11X,ZNF638,DDHD2,GPM6B,ZEB1,PTBP2,PCDHGA3,GRIK2,LEFTY2,DAAM2,CDC42,PCSK2,MAGI1,ZNF384,PIRT,PFKFB3,KIAA1549L,OPALIN,DNAJC12,SLC36A4,NSD2,FAAP20,CRLS1,FEZ1,PRKAB2,DOCK7,MASP1,BRINP3,PLPPR5,DNAJC6,CA10,BDNF-AS,PTHLH,CEP170,CSDE1,PTPRZ1,KCNH1,KCNK2,KCNN3,KCNQ2,PID1,ABI1,DSCAM,ABCC9,PHC2,ABI2,ARHGAP12,TMEM100,EPB41L2" MicroRNA hsa-let-7i:mirSVR_lowEffct hsa-let-7i:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.39E-30 1.83E-26 2.83E-29 2.60E-28 98 1947 "RABEPK,PRR5L,ACER3,CDHR1,MEG3,RTKN,F3,GALNT13,SORCS1,ERMN,TUBB4A,TOMM40L,SNX32,HOGA1,SCN4B,ASIC4,HPCAL4,CDC42BPA,ANK1,ANK2,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,MSR1,SLC8A2,SLCO1A2,USP33,B3GALT2,TNIK,ZSWIM8,NMNAT2,ADAM15,NPAS3,NDUFA5,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,GPR37L1,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,LRP8,CSDE1,MED24,BLOC1S6,CDH20,PTPRD,PLPPR4,KCNC1,RABGAP1L,KCNJ10,TMCC2,FAM57B,DSCAM,RASGRF1,DTNA,BSDC1,ABCC9,SLC6A15,NUP214,ELAVL4,EPB41L2,UEVLD" MicroRNA hsa-miR-1236:mirSVR_highEffct hsa-miR-1236:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.48E-30 1.88E-26 2.91E-29 2.67E-28 79 1279 "LOC100128239,NDRG2,SLITRK1,TMEM156,NLGN4X,CHST15,TOMM40L,SNX32,TESK2,MOG,SELL,PPFIA1,DOCK10,CACHD1,SYBU,API5,RUFY2,CGREF1,ASPH,BRINP2,SMARCE1,RCOR3,ZSWIM8,ARPP21,NFASC,NCAM1,DCAF5,PCDH11X,ZNF638,UNC5D,PSRC1,GPM6B,DDR1,ZEB1,CAMK2G,GRIA1,GRIA2,GRIK2,LINC00839,FBXL16,CELF3,PAX6,PCSK2,MAGI1,ZNF384,PRMT8,HMGB1,CASC2,HERC2P3,JAM2,NLGN3,CADM1,KIAA1549L,UBTF,FLRT1,PRRX1,NSD2,CHD1L,PPP2R5C,MICAL2,NRSN1,BRINP3,SYNC,BDNF-AS,ELMO1,STMN4,ZC3H11A,OLFM3,CDH20,SMG7,PCDH15,PAK5,RFX4,RFX5,FAM135B,ZNF248,RBM12,ABI2,EPB41L2" MicroRNA hsa-miR-3128:mirSVR_highEffct hsa-miR-3128:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.50E-30 1.90E-26 2.92E-29 2.68E-28 72 1057 "ACTN2,ATAT1,ARID1A,MDM4,ADD3,SORCS1,TESK2,SCN3A,ITSN1,NTNG1,SLITRK3,NLGN1,PAAF1,ZNF365,SLC2A5,CCDC88A,TAGLN3,CAPRIN2,SON,CAB39,NPAS3,CLASP2,COLGALT2,BCL2L2,ALDH1L1,SEPT3,FAM168A,GLS,SYT4,DDHD2,BTRC,CACNA1E,GRIA2,GRIK2,CCKBR,DAAM2,PCDH9,PRMT8,PFKFB3,SERPINE2,NRXN1,PMP2,ACBD5,CNRIP1,MED1,PPP3CB,RBPJ,DZIP3,CTNND1,MAPK10,EDRF1,DPYSL5,LRRTM3,PLPPR1,PRDM2,BLOC1S6,ZC3H11A,PTPRD,PTPRZ1,KCNJ11,ARNT2,KCNMA1,PEX5,PLEKHB2,DSCAM,ABCC9,SLC6A15,ZYG11B,JMJD1C,SLC4A10,ELAVL4,C2orf80" MicroRNA hsa-miR-148a:mirSVR_highEffct hsa-miR-148a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.82E-30 2.07E-26 3.18E-29 2.92E-28 75 1152 "PRR5L,RTN3,FAM43B,F3,FCGR1A,LRRTM4,FGF14,SELL,USP28,APBB1,MIER1,SLC1A7,RUFY2,SPHKAP,ASPH,ATP1A2,DKK3,USP33,SON,SOX5,DNER,SMOC1,NCDN,RGL1,NEUROD1,SYT4,DDHD2,UNC5D,GPM6A,ZEB1,TCF12,SYT6,GRIA1,CCKBR,MFSD2A,FBXL16,TJP1,TNFRSF1B,HPS5,TNS1,PCDH9,TPM3,MAGI1,PDE1A,PDE1C,PDYN,HPSE2,GDAP1L1,CADM1,P2RY12,POU3F2,CHD1L,PTPA,FEZ2,ATRNL1,RAB39A,IGSF1,CTNND1,MAPK10,SPIRE1,SYNC,PTHLH,PTPRD,SMG7,NTM,KCNK2,PCDH15,KCNN3,DLG2,DLG3,TMEM255A,DNM2,C12orf4,RTN4,C2orf80" MicroRNA hsa-miR-154*:mirSVR_lowEffct hsa-miR-154*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.19E-30 2.27E-26 3.49E-29 3.20E-28 89 1624 "TMEM74,LGR4,ARID1A,WAC,ADORA3,LRRC7,BCAR3,ELMOD1,ANK3,CNIH2,PKP4,APC,GPAM,CACHD1,ST3GAL3,SHTN1,AQP4,ZNF365,RUFY2,CCDC88A,DACH2,SLCO1A2,ASPH,TMEM108,USP33,SON,KIF1B,CPLX2,DNER,COLGALT2,PCDH11X,KAZN,TMEM136,TBX15,PRUNE2,CACNB2,GRIA1,ADAMTS8,MAEL,CDC42,C1orf94,PCSK2,MAGI1,ZMYND8,CHGA,ZBED5,HNRNPK,NEGR1,NXPH1,ACBD5,MFSD4A,ETNPPL,PTPA,DOCK7,PKN2,PLD5,CTNND2,PUM1,PROX1,WBP1L,SYTL2,ZNF385B,PTCH1,CNIH3,PRTFDC1,CEP170,STMN4,KCNA2,KCNA6,PTPRZ1,RABGAP1L,PEX5,DLG2,RAB5B,TMEM255A,SLC17A6,FAM66C,DSCAM,PAK5,SLC6A15,RFX4,RGS7,ATL1,RPRD1A,GPR61,ABI2,SLC4A10,EPB41L2,LRRC23" MicroRNA hsa-miR-146a*:mirSVR_highEffct hsa-miR-146a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-30 2.37E-26 3.64E-29 3.34E-28 89 1625 "ACER3,MAP6,WLS,SCN3A,LRRC7,ELMOD1,SOX6,CDC42BPA,USP28,SH3GL2,DOCK10,CACHD1,ST3GAL3,STK32C,ZNF365,SFMBT2,MSR1,NAXD,USP33,SON,AHCYL1,KIF1B,CPLX2,DNER,NPAS3,NCAM1,ALDH1L1,DCAF5,NEUROD1,SEMA4A,GNAS,DDHD2,ANO4,ACSL6,CACNA1E,TCF12,VXN,AKNA,GRID1,CRB1,TMEM257,LGI1,TPM3,PCSK2,MAGI1,ZNF384,TMEFF2,TLX1,CADM1,A2ML1,TJP2,BTF3L4,PRRX1,CP,POU3F2,PTPA,PPP2R5C,FEZ2,OSBPL3,PRKAB2,DZIP3,FMN2,RAB39A,NRSN1,PUM1,LRRTM3,PTCH1,PLPPR1,PRDM2,PTPRD,KCNC1,KCNJ10,KCNK1,SNX27,CAB39L,KLRC2,TMEM255A,RAP1GAP,FAM13C,DTNA,RTN4,PAK5,SLC6A15,ZYG11B,INSYN2,ARHGEF10L,YY1AP1,OLIG2,PRRT4" MicroRNA hsa-miR-634:mirSVR_lowEffct hsa-miR-634:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-30 2.75E-26 4.21E-29 3.86E-28 86 1523 "ACER3,MAP6,TMEM74,MBP,SYT9,ADGRV1,RTKN,MDM4,NDRG2,CDC7,SNX30,TESK2,LRRC7,MOG,SFPQ,ERICH3,ANK2,PPFIA1,ITSN1,PKP4,CLSTN1,SLC2A5,MSRA,SPHKAP,SLIT1,CADM3,GAD2,IDI2-AS1,NFASC,ALDH1L1,ASTN2,DCLK2,GNAS,CAMTA1,ADGRL3,CACNA1E,CECR2,VXN,VSTM2A,GRIK2,TF,MFSD2A,CELF3,TMEM257,ZDHHC22,C1orf94,SEZ6L,ZNF384,PDE1A,CASC2,ARHGAP22,KIAA1549L,A2ML1,OPALIN,BTF3L4,FAT3,MFSD4A,RGS6,FEZ1,NCAN,RBPJ,USP54,NRSN1,NOS1AP,PROX1,TOX,SYNC,PSMD13,CA10,RGMA,BLOC1S6,OCIAD1,PTPRE,PTPRO,KCNJ10,TMCC2,KCNN3,NKAIN1,TMEM255A,DNM2,RAP1GAP,ABI1,ZNF248,RBM12,SLC4A10,EPB41" MicroRNA hsa-miR-372:mirSVR_highEffct hsa-miR-372:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.18E-30 2.80E-26 4.29E-29 3.93E-28 81 1353 "EPS8,SYT9,LGR4,MDM4,AMER2,GPR158,HPCAL4,ANK2,MAGI3,CCDC80,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,RCOR3,MYT1L,TNIK,ARPP21,LMO3,CLASP2,DCAF5,RGL1,NEUROD1,ARHGEF7,CAMTA1,UNC5D,CNDP1,GPM6A,ZEB1,SYT6,VSTM2A,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,TGFBR3,AIFM1,HPS5,TNS1,PCDH9,MAGI1,ACOT7,BEST3,HMGB1,TMEFF2,NRXN1,PRRX1,SPATA6,FAAP20,ACBD5,CNRIP1,PPP3CB,FEZ2,PRKACB,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRDM2,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,RABGAP1L,PCDH15,KCNMA1,HS3ST4,SLC17A6,FAM13C,PAK5,SLC6A15,CRTAC1,RET,TMEM100,UEVLD" MicroRNA hsa-miR-3129:mirSVR_highEffct hsa-miR-3129:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.19E-30 2.81E-26 4.29E-29 3.94E-28 74 1126 "ARID1A,RTKN,MDM4,CLIP1,ADD3,WAC,SORCS1,SLC44A5,TESK2,LRRTM4,LINC00461,BCAR3,ELMOD1,MOBP,MOG,ERICH3,ANK2,CNIH2,NTNG1,ZCCHC17,TACC2,RUFY2,SLC8A3,SHANK2,CADPS,CAPRIN2,ASTN1,ATM,PHYHIPL,DKK3,USP33,SOX5,EMC1,NPAS3,LMO3,CLASP2,PCDH11X,ZNF638,KAZN,GPM6A,CACNB2,EML4,VSTM2A,TMEM25,INA,MAEL,DCLK1,PCSK2,PDE3B,PDE4B,ANO5,MS4A7,SERPINE2,SLC25A27,NXPH1,RNF14,KCNT2,OSBPL3,USP54,FGFR1OP2,SYTL2,SPIRE1,BDNF-AS,HP1BP3,PTPRE,C1orf109,PTPRZ1,NTM,DLG2,KIF2A,DTNA,JMJD1C,ATL1,SH3GLB1" MicroRNA hsa-miR-518a-5p:mirSVR_highEffct hsa-miR-518a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.53E-30 2.99E-26 4.55E-29 4.18E-28 80 1321 "ACLY,EYA1,ATAT1,WLS,KCNIP2,CLIP1,TOMM40L,SCN4B,FGF14,MOG,SH3GL2,APBA2,DOCK10,SESN3,ZCCHC17,ZNF365,MIER1,SLC1A6,RUFY2,SLC8A3,ASCL1,DLL3,NAXD,RCOR3,ATM,ATP1A2,PALLD,DKK3,SOX5,ZCCHC24,KIF1B,RAP1GAP2,NCAM1,ZNF302,NEUROD1,RND1,AJAP1,VAMP1,TBX15,GPM6B,LRIT2,ZEB1,TCF12,OLR1,LGI1,MAGI1,HMGB1,HERC2P3,NRXN1,NOMO2,A2ML1,P2RY12,ACBD5,CNRIP1,RNF14,PPP3CB,PRKACB,PUM1,PLPPR5,DNAJC6,CA10,BLOC1S6,OCIAD1,RABGAP1L,KCNK2,KCNMA1,KCNN3,TMEM255A,SLC25A48,DSCAM,FAM13C,ZYG11B,RET,INSYN2,ARHGEF10L,PIANP,RPRD1A,SLC4A10,ELAVL4,BAALC" MicroRNA hsa-miR-527:mirSVR_highEffct hsa-miR-527:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.53E-30 2.99E-26 4.55E-29 4.18E-28 80 1321 "ACLY,EYA1,ATAT1,WLS,KCNIP2,CLIP1,TOMM40L,SCN4B,FGF14,MOG,SH3GL2,APBA2,DOCK10,SESN3,ZCCHC17,ZNF365,MIER1,SLC1A6,RUFY2,SLC8A3,ASCL1,DLL3,NAXD,RCOR3,ATM,ATP1A2,PALLD,DKK3,SOX5,ZCCHC24,KIF1B,RAP1GAP2,NCAM1,ZNF302,NEUROD1,RND1,AJAP1,VAMP1,TBX15,GPM6B,LRIT2,ZEB1,TCF12,OLR1,LGI1,MAGI1,HMGB1,HERC2P3,NRXN1,NOMO2,A2ML1,P2RY12,ACBD5,CNRIP1,RNF14,PPP3CB,PRKACB,PUM1,PLPPR5,DNAJC6,CA10,BLOC1S6,OCIAD1,RABGAP1L,KCNK2,KCNMA1,KCNN3,TMEM255A,SLC25A48,DSCAM,FAM13C,ZYG11B,RET,INSYN2,ARHGEF10L,PIANP,RPRD1A,SLC4A10,ELAVL4,BAALC" MicroRNA hsa-miR-338-5p:PITA hsa-miR-338-5p:PITA_TOP PITA 5.60E-30 3.04E-26 4.61E-29 4.23E-28 62 773 "EYA1,F3,CLIP1,GPR158,KIAA1109,LRRC7,SEMA6A,ELMOD1,SOX6,SGIP1,CDC42BPA,SH3GL2,PPM1E,MAGI3,API5,SLC1A2,ARHGAP5,CAPRIN2,RCOR3,PALLD,MYT1L,ZCCHC24,DNER,SPART,CLASP2,PCDH11X,NKX2-2,GNAS,CAMTA1,CAMSAP2,ACSL6,PSD3,GRIA2,GRIA4,DAAM2,PCDH9,RBFOX2,MAGI1,PDE4B,NEGR1,NXPH1,POU3F2,PPP2R5C,MICAL2,ATRNL1,RBPJ,PKN2,PUM1,KIAA0408,LRRTM3,PTCH1,DNAJC6,JAKMIP2,PTPRD,TMEM255A,SLC17A6,GOPC,FAM13C,JMJD1C,RGS7,SLC4A10,EN2" MicroRNA hsa-miR-635:mirSVR_lowEffct hsa-miR-635:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.83E-30 3.16E-26 4.79E-29 4.40E-28 86 1526 "RABEPK,ZFYVE27,CNTNAP3,ACTN2,FAM43B,WLS,WAC,FABP7,TESK2,FGF1,HPCAL4,PDZD4,SORBS1,ST3GAL3,AQP4,MSR1,DACH2,SORCS3,PALLD,DKK3,USP33,SON,GART,ADGRB2,RAP1GAP2,C11orf87,BCL2L2,RGL1,SLCO1C1,ARHGEF7,GLS,VAMP1,ZNF638,KAZN,GNG4,GOLGB1,TMEM136,CAMK2G,GRIK2,TF,LEFTY2,USP2,TLL2,TMEM257,ZFP91,REPS2,PADI2,ARHGAP19,MAGI1,PIRT,FNDC5,CHGA,NEGR1,NMT2,FTO,VAV2,PLXNB3,SLC25A27,BEST1,RNF14,SNCAIP,RGS6,ATRNL1,NCAN,RBPJ,PLPP4,FAM131B,ECE2,TOX,WBP1L,SYTL2,SYNC,BDNF-AS,CNIH3,COPS7A,KCNC1,KCNH1,KCNJ10,KCNJ11,KCNK1,RAD52,FAM66C,RALGDS,C12orf4,RTN4,PIANP" MicroRNA hsa-miR-28-5p:mirSVR_lowEffct hsa-miR-28-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.62E-30 3.58E-26 5.43E-29 4.98E-28 90 1670 "LDLRAD3,NDRG2,ADCY2,SLITRK1,WAC,SORCS1,TUBB4A,GPR158,MOG,C1orf61,SOX6,SELL,ANK2,SH3GL2,NTNG1,SYBU,SLC1A7,URGCP,NSG2,LGI3,TAGLN3,NAXD,BRINP2,DKK3,GABBR1,MYH7,ARPP21,IDI2-AS1,ADAM15,NCAM1,CLASP2,ALDH1L1,KIRREL3,NEUROD1,SEPT3,CASTOR3,ZNF638,POPDC3,ROBO3,BTRC,PRUNE2,VXN,GRIA4,GPR88,TIE1,PTGDR2,MAGI1,BEST3,PFKFB3,PLEKHB1,CASC2,JAM2,GDAP1L1,KIAA1549L,UBTF,DNAJC12,ST8SIA5,C11orf49,MFSD4A,CHD1L,SF1,PTPA,ATRNL1,VCAN,RIMS4,PRKAB2,DOCK7,SDC3,CMTM5,PLD5,IGSF1,ECE2,NOS1AP,MASP1,RIMS3,PLPPR5,SYNC,LRRTM3,HP1BP3,KCNK1,NKAIN1,WIPF2,RFX4,RFX5,FAM135B,PHC2,RNF220,SSPN,CACNG7,SH3GLB1" MicroRNA hsa-miR-675*:mirSVR_lowEffct hsa-miR-675*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.01E-30 3.80E-26 5.74E-29 5.27E-28 73 1100 "RABEPK,ACLY,SYT9,LGR4,CLIP1,FCGR1A,LRRTM4,KIAA1109,LRRC7,MOBP,SOX6,ERICH3,ITSN1,ANXA7,SLITRK3,PAAF1,ZNF365,RUFY2,SCG3,LGI3,EIF4G3,DKK3,SON,B3GALT2,ZSWIM8,ADGRB2,ALDH1L1,GFAP,NEUROD1,PCDH11X,NHLH1,ANO4,GRID1,TGFBR3,P2RX7,TJP1,PDE3B,CIART,HMGB1,ANO5,CASC2,NRXN1,PMP2,BTF3L4,NSD2,MFSD4A,POU3F2,SNCAIP,NKAIN4,NCAN,FMN2,CTNND2,PROX1,KIAA0408,MASP1,ANKS1B,LRRTM3,PTAFR,DNAJC6,CA10,CADM2,PRDM2,OLFM3,PTPRD,PTPRE,KCNK2,DNAH9,C12orf4,RASGRF1,DTNA,RFX5,JMJD1C,INSYN2" MicroRNA hsa-miR-216a:mirSVR_lowEffct hsa-miR-216a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.06E-30 3.82E-26 5.77E-29 5.30E-28 97 1928 "ACER3,CDHR1,MBP,ATAT1,CSMD2,ADAR,WAC,NLGN4X,CHST15,TOMM40L,GOLGA7B,SOX6,SELL,AMPH,ASRGL1,USP28,PPFIA1,PKP4,MAGI3,NLGN1,ST8SIA1,API5,RUFY2,MSR1,SLC8A2,CCDC88A,DACH2,SPHKAP,CAPRIN2,BRINP2,ASTN1,SMARCE1,MEGF11,SOX1,SOX5,KIF1B,NAP1L2,STOX1,GFRA1,NFIA,PCDH11X,OS9,LUZP2,WWC1,NEU4,AZIN2,PTBP2,CAMK2G,GRIA1,RFFL,TMEM25,INA,TLL2,PAX6,TNR,DCLK1,RBFOX2,TPM3,PCSK2,PDE3B,ZMYND8,HMGB1,ANO5,MS4A7,NMT2,CCSER2,VAV2,PLXNB3,SPATA6,ACBD5,CRLS1,SNCAIP,RGS6,OSBPL3,ATRNL1,DZIP3,NRSN1,NOS1AP,TUBB2B,PRDM2,HP1BP3,CEP170,STMN4,DLG2,CAB39L,DNAH9,RAB5B,SLC25A18,GOPC,INSYN2,ARHGEF10L,ZNF248,VANGL2,SIDT2,RBM12,ELAVL4,RPE65" MicroRNA hsa-miR-548v:mirSVR_lowEffct hsa-miR-548v:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.34E-30 3.98E-26 6.00E-29 5.50E-28 86 1531 "PRR5L,ACER3,MAP6,ASIC1,MBP,ARID1A,MDM4,CSMD3,SLITRK1,SORCS1,ERMN,NLGN4X,LINC00461,FGF14,SEMA6A,FGR,BBOX1,MOBP,SELL,AMPH,ERICH3,ITSN1,ST3GAL3,DACH2,SCG3,LGI3,ASPH,SNAP25,SON,WDTC1,SOX5,SALL3,TTLL9,KIF1B,NAP1L2,SPART,C11orf87,CLASP2,NEUROD1,SLCO1C1,GLS,CAMTA1,GPM6A,ZEB1,AKNA,RFFL,TLL2,TNFRSF1B,CDC42,PADI2,CDH10,RBFOX2,TPM3,NMT2,A2ML1,CCSER2,FTO,FAM181B,NSD2,NXPH1,ACBD5,MFSD4A,PTPA,TENM4,RGS6,FMN2,KIAA1755,PLPP4,PHYHIP,TOMM20,ZNF385B,CA10,PLPPR1,ZC3H11A,KCNA4,KCNA6,PTPRZ1,KCNH1,SV2A,RABGAP1L,KCNK2,SLC17A6,ATG16L1,FAM13C,NUP214,RFX5" MicroRNA hsa-miR-888*:mirSVR_highEffct hsa-miR-888*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.68E-30 4.16E-26 6.26E-29 5.74E-28 74 1133 "RABEPK,PRR5L,LGR4,EYA1,LDLRAD3,ARID1A,WLS,F3,SORCS1,SLC44A5,LRRTM4,ELMOD1,DOCK10,DGKD,NLGN1,SLC1A7,BCO1,ARHGAP5,NSG2,SPHKAP,RCOR3,SNAP25,ATP1A3,PHYHIPL,USP33,ARPP21,SALL3,NPAS3,NDUFA5,ZNF302,PCDH11X,ZNF638,SYT4,DCLK2,UNC5D,ZEB1,PTBP2,GRIK2,INA,TLL2,CDC42,PCDH8,PDE4B,HMGB1,SULT4A1,SLC25A27,SPATA6,ETNPPL,MED1,SF1,CRMP1,CRLS1,KCNT2,FEZ2,RAB39A,PKN2,PMEPA1,CADM2,ZC3H11A,KCNA2,PTPRD,PTPRO,KCNK2,PCDH15,KIF2A,SLC6A15,RET,JMJD1C,FAM135B,RBM12,RPRD1A,SLC4A10,EPB41,RCAN2" MicroRNA hsa-miR-600:mirSVR_highEffct hsa-miR-600:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.02E-30 4.35E-26 6.53E-29 6.00E-28 68 950 "EPS8,RCSD1,MDM4,FGR,MOBP,FOXG1,ANXA7,NTNG1,SHTN1,CCDC88A,SLIT1,RCOR3,MYT1L,ZSWIM8,AHCYL1,ARPP21,NASP,C11orf87,CLASP2,ERBIN,SEPT3,ZNF638,UNC5D,KLHL4,TCF7L2,TCF12,PTBP2,NUMA1,GRIA2,VWCE,OLR1,INA,MAEL,TNS1,PCDH8,TPD52,MAGI1,ZBED5,TMEFF2,ST8SIA5,FTO,MEAF6,PRRX1,CRLS1,SNCAIP,PPP3CB,RGS6,MICAL2,RBPJ,DZIP3,KLK6,ANKS1B,ZNF385B,PRDM2,MAGI2,KCNA4,PTPRD,SMG7,RABGAP1L,PCDH15,PEX5,ABI1,DTNA,RFX4,RPRD1A,CBLN2,SLC4A10,EPB41" MicroRNA hsa-miR-4296:mirSVR_lowEffct hsa-miR-4296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.38E-30 5.08E-26 7.63E-29 7.00E-28 81 1365 "ZFYVE27,MBP,EYA1,FAM43B,WLS,DSCAML1,SLITRK1,ADORA1,ADORA3,GPR158,FGF1,ASIC4,SELL,ANK3,RASA3,CNIH2,APBB1,KIAA1614,MADD,PKNOX2,SLC6A9,LGI3,SMARCE1,KBTBD12,ATM,TTLL9,ADGRB2,NCAM1,ALDH1L1,SMOC1,KIRREL3,SEPT3,ZNF638,GNAS,TBX15,PRUNE2,NUCB1,GRID1,CYB561A3,OPCML,TNFRSF1B,TPM4,MAGI1,PRMT8,SCRG1,TLX1,KIAA1549L,PIK3CD,UBTF,NMT2,CCSER2,OPALIN,VAV2,CELF5,PRRX1,SPATA6,NSD2,FAT3,RGS6,KCNT2,ATRNL1,SDC3,PLPP4,USP54,ARHGEF4,NRSN1,ECE2,MASP1,DPYSL5,SMG7,KCNMA1,WIPF2,RALGDS,RASGRF1,GNE,ZNF248,SEC61A2,CACNG7,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-4288:mirSVR_lowEffct hsa-miR-4288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.66E-30 5.23E-26 7.85E-29 7.20E-28 86 1537 "ZFYVE27,TMEM74,EXTL1,CSMD2,MDM4,CLIP1,PLEKHG5,DSCAML1,SORCS1,SNX30,FOXRED2,DISP3,GOLGA7B,PPFIA1,NTNG1,AQP4,MT3,DACH2,SCMH1,SPHKAP,NAXD,C10orf105,ATP1A2,SOX5,CADM3,SALL3,KIF1B,NCAM1,ALDH1L1,DCAF5,FGF17,ADHFE1,ARHGEF7,MMD2,WWC1,ANO4,CACNA1A,TCF7L2,BRSK2,GRIA2,GRIA4,ADAMTS8,OPCML,CRB1,MFSD2A,P2RX7,TMEM9,TLL2,PADI2,CDH8,CDH10,RBFOX2,CASC2,NLGN3,KIAA1549L,NRXN2,TJP2,CELF5,MFSD4A,SF1,PPP2R5C,PPP3CB,NCAN,PRKAB2,PRKACB,DZIP3,PKN2,BRINP3,TOX,BLOC1S6,KCNH1,PCDH15,PEX5,KLRC3,SLC25A48,PARP11,GNE,DTNA,PAK5,L1CAM,ABCC9,RET,JMJD1C,TTLL7,SEC61A2,BAALC" MicroRNA hsa-miR-186:PITA hsa-miR-186:PITA_TOP PITA 9.99E-30 5.41E-26 8.10E-29 7.43E-28 63 809 "EYA1,ADAR,KLHL32,SCN3A,BCAR3,ERICH3,CDC42BPA,ANK3,RASA3,NTNG1,SLC1A2,ARHGAP5,CADPS,BRINP2,SNAP25,MYT1L,ZCCHC24,CAB39,NPAS3,NASP,LMO3,CLASP2,CAMTA1,BTRC,ACSL6,EML4,VXN,SYT6,PSD3,GRIA2,GRIA4,TMEM257,ZFP91,CDC42,CDH10,RBFOX2,PCSK2,PDE3B,ADGRG1,HMGB1,SERPINE2,NEGR1,MEAF6,BEST1,NXPH1,ATRNL1,PKN2,KIAA0408,RIMS3,SYNC,LRRTM3,PMEPA1,CADM2,CSDE1,ZC3H11A,KCNA1,PTPRO,KCNK2,SNX27,PID1,SLC17A6,PAK5,SLC6A15" MicroRNA hsa-miR-214*:mirSVR_lowEffct hsa-miR-214*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-29 5.47E-26 8.17E-29 7.50E-28 80 1333 "ASIC1,ACLY,ECSIT,ATAT1,RXRG,TOMM40L,SNX32,TRIM46,PPFIA1,ITSN1,PKP4,PPM1E,SLC1A6,NSG2,ASTN1,SNAP25,GABBR1,ARPP21,STARD10,NFASC,NDUFA5,PHLDB1,FAM168A,GLS,PCDH11X,BTRC,ADGRL3,WWC1,ANO4,AZIN2,TMEM151B,VXN,SYT6,AKNA,GRID1,RFFL,ATP13A2,CELF3,MAEL,CDC42,PTGDR2,RBFOX2,TPM3,ZNF384,PDE3B,ZMYND8,MS4A7,CHRNB2,CPT1C,A2ML1,CCSER2,PMP2,MEAF6,PRRX1,PACSIN1,SF1,SNCAIP,PRKACB,KIAA1755,PRKCZ,ARHGEF4,CTNND2,MASP1,ZBTB16,TOX,WBP1L,TOMM20,CNIH3,PRDM2,MAGI2,PTPRO,AK5,DLG2,CAB39L,RAB3IL1,DSCAM,DTNA,CAMK1G,RET,ARHGAP12" MicroRNA hsa-miR-520c-3p:mirSVR_highEffct hsa-miR-520c-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.09E-29 5.89E-26 8.79E-29 8.06E-28 81 1368 "EPS8,LGR4,MDM4,AMER2,GPR158,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,RCOR3,MEGF11,MYT1L,TNIK,CAB39,ENKUR,ARPP21,SALL3,LMO3,DCAF5,RGL1,NEUROD1,SLCO1C1,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,GPM6A,CACNA1E,TCF7L2,ZEB1,VSTM2A,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,HPS5,TNS1,C1orf94,PCDH9,LGI1,PCSK2,MAGI1,CASC2,PRRX1,SPATA6,ACBD5,CNRIP1,FEZ2,PRKACB,FMN2,PKN2,IGSF1,MASP1,TOX,SYNC,ITGAV,PTHLH,CADM2,HP1BP3,RGMA,CSDE1,BLOC1S6,ZC3H11A,OLFM3,PTPRD,KCNMA1,HS3ST4,OLIG1,RAB5B,FAM13C,PAK5,ABCC9,SLC6A15,TMEM100" MicroRNA hsa-miR-153-3p:TargetScan hsa-miR-153-3p TargetScan 1.11E-29 5.98E-26 8.92E-29 8.18E-28 56 623 "ABAT,ARID1A,KCNIP2,CHST15,GPR158,SCN3A,ANK1,ANK3,APC,JAKMIP3,PKNOX2,FYN,ATP2B2,CADM3,NMNAT2,NFASC,CLASP2,DCAF5,NEUROD1,FAM168A,NFIA,PCDHGA3,CAMK2G,RFFL,GRIK2,GRIK3,GRIK4,ADAMTS8,KCNK10,PCDH8,DCLK1,MAGI1,PDE3B,HNRNPK,NMT2,CCSER2,FAT3,CRMP1,PRKAB2,PRKACB,PKN2,PROX1,DPYSL5,PTCH1,CADM2,PRDM2,KCNA1,KCNA4,PTPRD,KCNA6,NAV2,DLG2,CALN1,FAM135B,EFNA3,ELAVL4" MicroRNA hsa-miR-200c*:mirSVR_lowEffct hsa-miR-200c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-29 6.12E-26 9.11E-29 8.36E-28 79 1302 "EPS8,CSMD2,WLS,RTKN,KCNIP2,CSMD3,ADAR,F3,KLHL32,ADD3,NLGN4X,TESK2,LRRC7,SEMA6A,ELMOD1,MOG,C1orf61,AMPH,ANK3,CCDC80,NSG2,LGI3,DDX25,ADGRA1,DKK3,SON,KIF21B,ARPP21,DNER,RCOR2,ARHGEF7,CASTOR3,GNAS,DDHD2,CAMTA1,UNC5D,GPM6A,CACNA1E,CACNB2,TCF12,PTBP2,VXN,GRIA2,GRIA4,MFSD2A,GUCY1A1,ZFP91,PCDH9,TPM3,MAGI1,ZNF384,PDE2A,PDE4B,HMGB1,SCRG1,HNRNPK,CADM1,ANLN,CNTN1,BTF3L4,PRRX1,PPP3CB,FEZ1,DOCK7,PLD5,PRKCZ,USP54,PUM1,EDRF1,ZNF385B,PRTFDC1,KCNA4,KCNK1,PCDH15,KCNMA1,JMJD1C,FAM135B,VWA5A,ARHGAP12" MicroRNA hsa-miR-548q:mirSVR_lowEffct hsa-miR-548q:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-29 6.22E-26 9.24E-29 8.48E-28 83 1437 "ASIC1,CNTNAP3,SYT9,ATAT1,GALNT13,FCGR1B,LRRTM4,LRRC7,SEMA6A,ASIC4,HPCAL4,ANK1,PPFIA1,BCAN,NLGN1,RPH3A,SMARCE1,RCOR3,B3GAT1,ATM,NRG3,PALLD,SCN3B,B3GALT2,CAB39,NMNAT2,ARPP21,LHFPL4,TTLL9,ALDH1L1,SMOC1,RGL1,ARHGEF7,ASTN2,WWC1,VXN,VSTM2A,SPX,TMEM9,TLL2,TMEM257,CDC42,PDE3B,PIRT,ANO5,CHI3L2,HNRNPK,CPT1C,FTO,MEAF6,BEST1,BTF3L4,SLC36A4,CNRIP1,FEZ1,ATRNL1,PLCH2,RBPJ,NRSN1,FGFR1OP2,ANKS1B,PTCH1,BDNF-AS,CSDE1,STMN4,PTPRE,C1orf109,SRGAP3,KCNJ10,KCNK1,SNX27,SLC25A48,DTNA,ABCC9,ZYG11B,RFX4,JMJD1C,RGS10,INSYN2,SH3GLB1,ELAVL3,EPB41,SEZ6" MicroRNA hsa-miR-1294:mirSVR_lowEffct hsa-miR-1294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-29 6.30E-26 9.34E-29 8.57E-28 90 1683 "TTYH1,SERPINA3,ACER3,ASIC1,CDHR1,MEG3,EYA1,MRVI1,CLIP1,ADD3,PNMA8B,SORCS1,GRAMD1B,SNX30,CHST15,SCN4B,SOX6,SGIP1,CCDC80,TACC2,BCAS1,AQP4,RPH3A,SFMBT2,URGCP,RUFY2,SLC8A3,MT3,CCDC88A,CGREF1,CAPRIN2,MTR,ALDH4A1,ATM,NRG3,SCN3B,SON,WDTC1,ZCCHC24,TTC9B,NPAS3,NCAM1,OS9,GNAS,CAMTA1,CDK5R2,ADGRL3,PRUNE2,CACNB2,ZEB1,EML4,VXN,NUMA1,BRSK2,GRIA4,MFSD2A,DAAM2,PDE1C,PDE2A,IGFN1,CASC2,ANLN,CCSER2,MICAL1,BEST1,BTF3L4,SPATA6,CNRIP1,MFSD4A,SF1,RGS6,VCAN,FAM131B,ECE2,KIAA0408,PTAFR,PRTFDC1,HP1BP3,OLFM3,PTPRD,PTPRO,PCDH15,SLC25A48,ATG16L1,BSDC1,SLC6A15,JMJD1C,RGS10,FAM135B,PLEKHO1" MicroRNA hsa-miR-411:mirSVR_lowEffct hsa-miR-411:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-29 6.44E-26 9.53E-29 8.75E-28 78 1270 "SDE2,PRR5L,CDHR1,TMEM74,EYA1,MRVI1,ATAT1,CLIP1,SORCS1,FCGR1A,LRRC7,BBOX1,GOLGA7B,ELMOD1,FOXG1,MOG,APBA2,APC,SYBU,LRRC4C,API5,ARHGAP5,DACH2,SORCS3,SMARCE1,TMEM108,ATM,ATP1A2,NRG3,PHYHIPL,PALLD,SON,NCAM1,C11orf87,CLASP2,NDUFA5,STOX1,SEPT3,LUZP2,CAMSAP2,MYRF,TMEM136,ACSL6,CAMK2G,NUMA1,DAAM2,PAX6,MAGI1,ZNF384,PDE3B,ADGRG1,CADM1,KIAA1549L,NEGR1,PMP2,CNRIP1,SNCAIP,FEZ2,BRINP3,PTAFR,HP1BP3,ZC3H11A,PTPRE,PLPPR4,RABGAP1L,CCDC3,KIF2A,KLRC3,C12orf4,L1CAM,ABCC9,RFX4,RFX5,JMJD1C,ATL1,ZNF248,EPB41L2,RCAN2" MicroRNA hsa-miR-593:mirSVR_highEffct hsa-miR-593:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-29 6.98E-26 1.03E-28 9.47E-28 64 841 "LOC100128239,SYT9,DUSP27,EYA1,DSCAML1,ADORA3,LRRC7,FOXM1,FOLH1,SH3GL2,GPAM,ZCCHC17,SLC8A3,SOX10,ADAM15,CPLX2,DNER,NDUFA5,ERBIN,HEPN1,GLS,ASTN2,LUZP2,DCLK2,SEMA4A,CAMTA1,MMD2,ANO4,CACNA1E,LILRA1,TCF12,GPR88,CYB561A3,PTPN5,TNR,SEZ6L,PRMT8,CADM1,OPALIN,PLXNB3,SLC25A27,CP,PPP2R5C,KCNT2,FMN2,IGSF1,GON4L,PTHLH,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNC1,NTM,KCNJ10,PCDH15,DLG2,HS3ST4,FAM66C,DTNA,RPRD1A,EPB41,RCAN2,UEVLD" MicroRNA hsa-miR-765:mirSVR_highEffct hsa-miR-765:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-29 7.14E-26 1.06E-28 9.68E-28 71 1049 "TTYH1,ACHE,SYT9,RCSD1,ARID1A,WLS,MDM4,NDRG2,DSCAML1,ASIC4,MOG,ITSN1,SYBU,ZNF365,BCO1,MSR1,CCDC88A,SCMH1,DLL3,SNAP25,NCAM1,C11orf87,COLGALT2,SEPT3,SLCO1C1,C1QC,KAZN,ROBO3,CAMTA1,GNG3,TMEM136,DDR1,CACNB2,PCDHGA3,GRIA2,GRIA4,OMG,TMEM25,GUCY1A2,C1orf94,TPM3,PRMT8,PDYN,HPSE2,PFKFB3,FTO,BTF3L4,SF1,CSF3R,FEZ1,MICAL2,PLCH2,PKN2,IGSF1,MAPK10,PUM1,PLPPR1,ELMO1,MAGI2,KCNA1,SMG7,NTM,KCNJ10,NKAIN1,DTNA,RFX5,SEC61A2,SSPN,ABI2,OLIG2,SEZ6" MicroRNA hsa-miR-216b:mirSVR_highEffct hsa-miR-216b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.33E-29 7.17E-26 1.06E-28 9.71E-28 83 1440 "CDHR1,CSMD2,MDM4,CSMD3,KLHL32,SLITRK1,FCGR1A,CHST15,KIAA1109,FOXM1,USP28,PKP4,MIER1,BCO1,MSR1,LRRC55,SLC8A3,SLC14A1,CADPS,SPHKAP,BRINP2,SORCS3,ASTN1,ATP1A2,SOX1,SOX5,KIF21B,CAB39,SPART,C11orf87,ALDH1L1,SMOC1,DDHD2,ANO4,GPM6A,CACNA1E,CACNB2,TCF7L2,ZEB1,GPR19,VXN,GRIK2,INA,GUCY1A2,MAEL,TPM3,PRMT8,LRTM2,CASC2,FTO,VAV2,PMP2,BTF3L4,SPATA6,FAT3,ACBD5,CRLS1,PPP2R5C,PPP3CB,KCNT2,PRKACB,DZIP3,FAM131B,GON4L,PRDM2,BLOC1S6,OLFM3,KCNC1,PTPRO,KCNMA1,PEX5,PARP11,C12orf4,BSDC1,RFX4,RFX5,JMJD1C,INSYN2,ARHGAP12,SLC4A10,ELAVL3,EN2,RPE65" MicroRNA hsa-miR-513b:mirSVR_highEffct hsa-miR-513b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-29 7.41E-26 1.09E-28 1.00E-27 77 1240 "CNTNAP3,SYT9,ADGRV1,KLHL32,WAC,AGT,KIAA1109,FGF1,SLC30A10,ITSN1,LRRC4C,AQP4,RUFY2,DACH2,ASPH,DDX25,SNAP25,CCDC181,FYN,MYT1L,SOX5,ZCCHC24,GAD2,JPH4,SALL3,C11orf87,RGL1,ARHGEF7,GLS,SYT4,ROBO3,CAMTA1,ADGRL3,TCF7L2,PTBP2,EML4,GRIA4,GRID1,CRB1,TMEM257,ZFP91,MAEL,SEZ6L,PDE1A,PDE3B,PRMT8,CASC2,TMEFF2,CADM1,NEGR1,P2RY12,PACSIN1,NSD2,MED1,CRMP1,ATRNL1,DZIP3,FAM131B,TOMM20,SIRPA,ITGAV,CADM2,COPS7A,KCNA2,PLPPR4,KCNMA1,TMEM255A,FAM66C,RASGRF1,DTNA,FAM135B,SEC61A2,SFXN5,RAVER2,SLC4A10,EN2,RASGRP2" MicroRNA hsa-miR-651:mirSVR_lowEffct hsa-miR-651:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-29 7.50E-26 1.10E-28 1.01E-27 85 1510 "PRR5L,LDLRAD3,CSMD3,WAC,FABP7,SLC44A5,HOGA1,KIAA1109,SEMA6A,ITSN1,ANXA7,BCAS1,SLC7A14,PKNOX2,SLC14A1,CADPS,SLIT1,DLL3,DDX25,FYN,USP33,ARPP21,DNER,NASP,NCAM1,ALDH1L1,GFRA1,GLS,LUZP2,UNC5D,ADGRL3,PRUNE2,GPM6A,ATF7,TCF7L2,TCF12,VSTM2A,NUMA1,GRIA2,LEFTY2,INA,CDH8,DCLK1,PCSK2,LINC01102,NTSR2,ANO5,PFKFB3,KIAA1549L,SPATA6,NSD2,FAT3,NXPH1,CNRIP1,MFSD4A,SNCAIP,OSBPL3,ATRNL1,PHACTR3,DZIP3,EDRF1,WBP1L,PLPPR5,ZNF385B,PSMD13,SIRPA,DNAJC6,ITGAV,PTHLH,CADM2,CEP170,MAGI2,PLPPR4,SRGAP3,PCDH15,DLG2,TMEM255A,SLC17A6,RASGRF1,ABCC9,JMJD1C,ATL1,SYT15,RPRD1A,SEZ6" MicroRNA hsa-miR-3165:mirSVR_lowEffct hsa-miR-3165:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-29 7.60E-26 1.12E-28 1.02E-27 76 1208 "SERPINA3,ABAT,PRR5L,ACER3,ACTN2,WLS,SLC25A25,SLITRK1,PNMA8B,SNX32,BCAR3,GOLGA7B,UNC79,AMPH,ERICH3,ANK3,NTNG1,BCAN,SYBU,JAKMIP3,BCAS1,MIER1,SLCO1A2,SLIT1,ASTN1,SMARCE1,RCOR3,TMEM108,SNAP25,SOX10,ZSWIM8,NFASC,GJB1,ZNF638,NHLH1,DDHD2,NODAL,UNC5D,BTRC,WWC1,CACNB2,HAP1,CAMK2A,GRIA4,SHISA7,DAAM2,MAEL,TNS1,PDE2A,NLGN3,CADM1,ZFYVE9,SEMA5B,PLXNB3,MEAF6,COL9A2,CRMP1,TENM4,ATRNL1,RBPJ,PRKACB,PLPP4,CTNND1,MAPK8,ITGAV,HP1BP3,CSDE1,SV2A,RABGAP1L,KCNK1,NKAIN1,KLRC2,NUP214,RNF220,RPRD1A,UEVLD" MicroRNA hsa-miR-202:mirSVR_lowEffct hsa-miR-202:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-29 7.88E-26 1.16E-28 1.06E-27 79 1307 "ASIC1,LGR4,MEG3,LDLRAD3,ARID1A,RTKN,MDM4,KCNIP2,ADAR,ADARB2,CLIP1,DSCAML1,WAC,NLGN4X,TOMM40L,GPR158,KIAA1109,FOXG1,SGIP1,USP28,PPFIA1,ITSN1,BCAS1,USP16,URGCP,MSR1,MTR,PHYHIPL,B3GALT2,C11orf87,CLASP2,GLS,OS9,ACSL6,CACNB2,EML4,GRID1,GRIK2,GRIK3,ADAMTS8,GPR88,TGFBR3,TJP1,REPS2,PCDH9,ARHGAP19,ANO5,ARHGAP22,HEPACAM,NEGR1,ANLN,OPALIN,ST8SIA5,CNTN1,CELF5,BTF3L4,MFSD4A,MICAL2,RBPJ,PRKAB2,RAB39A,PKN2,PLD5,TUBB2B,LRRTM3,PRDM2,PTPRZ1,KCNJ10,PCDH15,SNX27,RAD52,DPP6,ATG16L1,ABCC9,SLC6A15,TTLL7,SEC61A2,ELAVL4,PRRT4" MicroRNA hsa-miR-1224-5p:mirSVR_lowEffct hsa-miR-1224-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-29 8.49E-26 1.24E-28 1.14E-27 89 1654 "DPF1,ZFYVE27,CDHR1,CEND1,CSMD2,ARID1A,NDRG2,KLHL32,ADCY2,GALNT13,SORCS1,ADORA1,SCN4B,FGR,GOLGA7B,ANK1,CNIH2,BCAN,SORBS1,ST3GAL3,STK32C,SHTN1,AQP4,ZNF365,SLC2A5,MSR1,SLC8A3,CADPS,CGREF1,ARFGAP1,KBTBD12,TMEM108,ATP1A2,NRG3,ZSWIM8,B4GALNT1,KIF1B,NFASC,C11orf87,FGF17,PCDH11X,ZNF638,SYT4,CAMTA1,MYRF,MMD2,ANO4,DDR1,CECR2,GRIA2,TF,CRB1,ZFP91,TNS1,PCDH9,DCLK1,LGI1,PIRT,FNDC5,CHRM1,CASC2,HEPACAM,KIAA1549L,NRXN2,NMT2,OPALIN,TJP2,PMP2,FAT3,NXPH1,PNKD,NKAIN4,RAB39A,IGSF1,ECE2,MASP1,DPYSL5,PRDM2,LRP8,COPS7A,KCNA1,OLFM3,KCNJ9,KCNK2,ATG16L1,PIANP,FGFBP3,RPE65,PRRT4" MicroRNA hsa-miR-1248:mirSVR_highEffct hsa-miR-1248:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-29 8.49E-26 1.24E-28 1.14E-27 84 1478 "TTYH1,ACER3,SYT9,EYA1,MDM4,NDRG2,SORCS1,FCGR1A,FGF1,AMPH,USP28,ITSN1,NTNG1,NLGN1,API5,RUFY2,LRRC55,SLC8A3,SLC14A1,SCG3,ASPH,ATP1A2,SON,GAD2,AHCYL1,JPH4,NPAS3,NDUFA5,CAMTA1,ANO4,TBX15,DDR1,CACNB2,PTBP2,VXN,ADAMTS8,GPR88,OLR1,CRB1,TMEM25,ZFP91,CD81,MAEL,CDC42,PDE3B,PDYN,HMGB1,MS4A7,ZBED5,JAM2,NRXN1,NEGR1,SLC25A27,PRRX1,NXPH1,MFSD4A,MED1,CRLS1,PPP2R5C,SNCAIP,RGS6,FEZ2,FEZ1,PRKCZ,ECE2,PROX1,FGFR1OP2,BDNF-AS,LRP8,SMG7,KCNK1,KCNK2,DLG2,CAB39L,FAM13C,DBX2,DTNA,ABCC9,RFX5,JMJD1C,INSYN2,SYT15,EN2,RCAN2" MicroRNA hsa-miR-15a*:mirSVR_lowEffct hsa-miR-15a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-29 8.71E-26 1.27E-28 1.17E-27 81 1376 "ACER3,SYT9,MRVI1,LDLRAD3,CSMD3,ADCY2,GRAMD1B,TOMM40L,LINC00461,GOLGA7B,PI16,PKP4,ST3GAL3,STK32C,ZNF365,MIER1,MSR1,PKNOX2,MT3,DACH2,NAXD,JPH4,KIF1B,SPART,NFASC,BCL2L2,DCAF5,RGL1,KIRREL3,ARHGEF7,SYT4,ASTN2,LUZP2,DCLK2,UNC5D,ANO4,PCDHGA3,CAMK2G,VSTM2A,GRIA2,TJP1,ZDHHC22,MAGI1,PDE3B,IGFN1,MS4A7,TLX1,NOMO2,CCSER2,OPALIN,CNTN1,PMP2,BTF3L4,NSD2,CHD1L,MED1,CRLS1,ATRNL1,USP54,MAPK8,EDRF1,NOS1AP,SYNC,LRRTM3,PRDM2,SHD,CEP170,CSDE1,CCDC3,DNAH9,RAB5B,TMEM255A,DPP6,ATG16L1,RASGRF1,RGR,SSPN,SH3GLB1,ARHGAP12,RCAN2,SEZ6" MicroRNA hsa-miR-34b:mirSVR_lowEffct hsa-miR-34b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-29 8.80E-26 1.28E-28 1.18E-27 94 1837 "ACER3,CNTNAP3,LGR4,RTN3,ACTN2,ADGRV1,ARID1A,ADCY2,SLITRK1,GALNT13,SNX30,FOXRED2,SLC44A5,LRRTM4,LRRC7,BCAR3,ELMOD1,ERICH3,USP28,PPM1E,MAGI3,GPAM,DGKD,SORBS1,CACHD1,SHTN1,MIER1,SFMBT2,SLC2A5,LRRC55,DACH2,SCG3,TMEM108,FYN,SCN3B,B3GALT2,JPH4,NAP1L2,NPAS3,ALDH1L1,NDUFA5,DCAF5,NCDN,RGL1,NEUROD1,GLS,SYT4,GNAS,CAMTA1,ACSL6,EML4,CECR2,VXN,VSTM2A,AKNA,GRIA2,GRIK2,GPR88,TJP1,AIFM1,TLL2,NEURL1,PCDH9,DCLK1,TPD52,PRMT8,BEST3,ANO5,TMEFF2,JAM2,DNAJC12,CNTN1,ETNPPL,ATRNL1,PLPP4,MAPK8,NOS1AP,MASP1,DPYSL5,DNAJC6,ITGAV,PLPPR1,PRDM2,CEP170,OCIAD1,SLC17A6,ABI1,RFX4,SH3GLB1,ABI2,FGFBP3,CBLN2,SLC4A10,OLIG2" MicroRNA hsa-miR-655:PITA hsa-miR-655:PITA_TOP PITA 1.74E-29 9.40E-26 1.37E-28 1.26E-27 62 789 "ACLY,EYA1,WLS,RTN1,SLITRK1,ADD3,LRRC7,SFPQ,APC,NTNG1,GAS7,CCDC80,SLITRK3,ST3GAL3,BCAS1,AQP4,SLC1A2,ARHGAP5,ASCL1,CAPRIN2,SMARCE1,EIF4G3,SOX1,B3GALT2,ZCCHC24,GPR162,DCAF5,NEUROD1,ARHGEF7,PCDH11X,SYT4,CAMSAP2,ADGRL3,CACNB2,GRIA4,RFFL,GRM3,PTPN5,GUCY1A2,CDC42,RBFOX2,PDE4B,ZMYND8,HEPACAM,PHACTR3,PTCH1,PMEPA1,CADM2,COPS7A,MAGI2,ZC3H11A,KCNA4,RAB5B,GOPC,FAM13C,JMJD1C,RGS7,PIANP,EN2,EPB41,EPB41L2,SEZ6" MicroRNA hsa-miR-892a:mirSVR_highEffct hsa-miR-892a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-29 9.69E-26 1.41E-28 1.29E-27 68 963 "CNTNAP3,MDM4,ADCY2,ERMN,NLGN4X,KIAA1109,MOBP,FOXG1,PPFIA1,PKP4,SH3GL2,DOCK10,NTNG1,SHTN1,ZNF365,MIER1,SLC8A3,CCDC88A,DACH2,RCOR3,TMEM108,PALLD,SOX5,ARHGEF7,ZNF638,UNC5D,PSRC1,KLHL4,TBX15,CACNA1E,ZEB1,TCF12,GRIK2,GPR88,PCDH8,PDE1C,ACOT7,NLGN3,MEAF6,BEST1,BTF3L4,SPATA6,NSD2,ACBD5,KCNT2,VCAN,PRKACB,PKN2,PLD5,CTNND2,SYTL2,ANKS1B,SYNC,LRRTM3,PLPPR1,LRP8,CEP170,MAGI2,KCNA6,C1orf109,SRGAP3,KCNMA1,TMEM255A,GOPC,FAM13C,ABCC9,RET,RGS7" MicroRNA hsa-miR-490-3p:mirSVR_lowEffct hsa-miR-490-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.87E-29 1.01E-25 1.47E-28 1.35E-27 82 1413 "ZFYVE27,SYT9,LGR4,RCSD1,ADGRV1,ATAT1,MDM4,FOXRED2,SCN4B,FGF1,SEMA6A,ELMOD1,FOXG1,SGIP1,PPFIA1,BCAS1,API5,LRRC55,ARFGAP1,MTR,SORCS3,RCOR3,MEGF11,SON,CAB39,TTLL9,FXYD6,NFASC,NCAM1,COLGALT2,BCL2L2,RGL1,NEUROD1,OS9,CAMTA1,GNG3,KLHL4,ANO4,PRUNE2,CACNA1E,SYT6,BRSK2,GRIK2,P2RX7,TMEM9,TMEM257,ZDHHC22,TNR,PDE4B,PIRT,BEST3,HMGB1,LRTM2,CCSER2,OPALIN,TJP2,ST8SIA5,MEAF6,NSD2,MED1,SF1,PPP2R5C,FEZ1,VCAN,PRKCZ,KIAA0408,LRRTM3,PMEPA1,KCNK1,DLG3,NKAIN1,WIPF2,DNAH9,RAB5B,SLC25A48,DPP6,RASGRF1,DBX2,ABCC9,VWA5A,SLC4A10,EPB41L1" MicroRNA hsa-miR-607:PITA hsa-miR-607:PITA_TOP PITA 1.88E-29 1.02E-25 1.48E-28 1.35E-27 67 934 "EPS8,SYT9,LDLRAD3,CSMD2,SLC25A25,CLIP1,KLHL32,ADD3,CDC7,FABP7,ERMN,NLGN4X,GPR158,KIAA1109,SFPQ,PKP4,DOCK10,GPAM,NLGN1,API5,SLC1A2,MYT1L,SOX10,NEK6,LMO3,CLASP2,ERBIN,ACSBG1,NFIA,CAMTA1,GNG3,CAMSAP2,UNC5D,CACNA1A,GPM6A,TCF12,PTBP2,GRIA2,TJP1,ZFP91,ATG4C,TMEFF2,NRXN1,NEGR1,NMT2,CCSER2,BEST1,FAT3,KCNT2,FEZ2,PHACTR3,RBPJ,CTNND2,MAPK10,KIAA0408,TOX,JAKMIP2,ZC3H11A,PTPRD,PCDH15,KIF2A,FAM13C,SLC6A15,FAM135B,RBM12,SLC4A10,EPB41L2" MicroRNA hsa-miR-3199:mirSVR_lowEffct hsa-miR-3199:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-29 1.06E-25 1.53E-28 1.41E-27 82 1414 "CDHR1,RTN3,SYNDIG1,CEND1,MEG3,PLEKHG5,ADD3,SORCS1,ERMN,TUBB4A,SNX32,LRRC7,UNC79,HPCAL4,ITSN1,PKP4,PPM1E,DOCK10,CLSTN1,MIER1,SFMBT2,LRRC55,SLC8A2,PDE8B,SMARCE1,B3GAT1,NRG3,ATP1A3,MEGF11,SCN3B,WDTC1,ADAM15,FXYD6,C11orf87,COLGALT2,GPR162,ADHFE1,NEUROD1,VAMP1,GNAS,CDK5R2,CNTN2,CACNA1E,PTBP2,NUCB1,GRIA1,LINC00839,TMEM9,ZFP91,CD81,PCSK2,ZNF384,PDYN,ASIC3,CHRM1,PLEKHB1,DUSP26,CCDC136,C11orf49,BEST1,CRMP1,TENM4,NKAIN4,VCAN,SDC3,PSD,ZNF385B,PRTFDC1,RGMA,SMG7,KCNMA1,DLG2,WIPF2,RAB5B,TMEM255A,RALGDS,ATG16L1,DTNA,RET,SEC61A2,GPR61,SLC4A10" MicroRNA hsa-miR-148a:mirSVR_lowEffct hsa-miR-148a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-29 1.12E-25 1.62E-28 1.49E-27 94 1843 "ZFYVE27,ACER3,ASIC1,ACHE,MBP,CSMD2,RTKN,MDM4,ADARB2,CLIP1,RTN1,ADCY2,GRAMD1B,LRRC7,ERICH3,ANK2,RASA3,NTNG1,SLITRK3,TACC2,SYBU,SHTN1,PKNOX2,MT3,CCDC88A,CAPRIN2,MTR,ASTN1,RCOR3,SNAP25,NRG3,EMC1,NCAM1,CLASP2,BCL2L2,ALDH1L1,ERBIN,RCOR2,HEPN1,AJAP1,GLS,TMEM136,DDR1,CAMK2A,NUMA1,OPCML,PTPN5,LEFTY2,USP2,ZDHHC22,RBFOX2,PDE2A,PDE3B,PDE4B,ZMYND8,TLX1,ZFYVE9,KIAA1549L,NRXN1,TJP2,FADS2,FTO,VAV2,PLXNB3,IFFO1,MED1,PRKCZ,MASP1,DPYSL5,LRRTM3,CADM2,ELMO1,PRDM2,HP1BP3,RGMA,CEP170,PTPRE,KCNH1,KCNK1,SNX27,DNAH9,SLC17A6,PLEKHB2,PARP11,ATG16L1,ZNF248,SEC61A2,SLC39A12,VWA5A,SLC4A10,EPB41,EPB41L2,UEVLD,BAALC" MicroRNA hsa-miR-1273d:mirSVR_lowEffct hsa-miR-1273d:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-29 1.42E-25 2.06E-28 1.89E-27 85 1524 "MEG3,ARID1A,WLS,CSMD3,ADAR,ADARB2,NLGN4X,HOGA1,AGT,ACTL6B,MOBP,SGIP1,ANK3,FOLH1,ITSN1,PKP4,DOCK10,ZNF365,MIER1,SLC7A14,MSR1,CSPG5,SLCO1A2,ASTN1,KBTBD12,SOX5,CADM3,KIF1B,LMO3,SMOC1,GFRA1,MLC1,KAZN,ADGRL3,CACNA1E,DIRAS1,CECR2,GRIK2,CRB1,KCNK10,RBFOX2,IGFN1,PRMT8,CASC2,JAM2,ARHGAP22,KIAA1549L,A2ML1,MEAF6,CELF5,PACSIN1,FAT3,NXPH1,MFSD4A,CHD1L,MED1,CRMP1,RGS6,MICAL2,DOCK7,FMN2,PKN2,NRSN1,TOX,ANKS1B,TOMM20,SYNC,ITGAV,ELMO1,PTPRE,NTM,NAV2,C12orf4,RASGRF1,ZYG11B,RFX4,FAM135B,ATL1,ARHGEF10L,PIANP,RBM12,SH3GLB1,ARHGAP12,RAVER2,YY1AP1" MicroRNA hsa-miR-365:mirSVR_lowEffct hsa-miR-365:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.78E-29 1.51E-25 2.17E-28 1.99E-27 76 1221 "EPS8,SERPINA3,ABAT,ADGRV1,ATAT1,ADAR,F3,GALNT13,FCGR1A,ELMOD1,MOBP,SOX6,ANK2,MIER1,SLC2A5,RUFY2,SLC8A2,NAXD,SORCS3,ATP1A2,SCN3B,KIF21B,ZSWIM8,ARPP21,KIF1B,NCAM1,C11orf87,COLGALT2,ERBIN,FAM168A,NFIA,LUZP2,GNAS,ROBO3,MMD2,ADGRL3,TMEM136,TBX15,VWC2,PTBP2,OPCML,ZDHHC22,KCNK10,DCLK1,IGFN1,PDYN,HAPLN2,HPSE2,LRTM2,SEMA5B,NMT2,SLC25A27,ACBD5,POU3F2,FEZ2,PRKACB,TOX,SPIRE1,JAKMIP2,BDNF-AS,KCNA1,KCNA4,KCNK2,PCDH15,TMEM255A,PLEKHB2,C12orf4,GNE,SLC6A15,ZYG11B,RET,RFX4,ARHGEF10L,ZNF248,EFNA3,RBM12" MicroRNA hsa-miR-877*:mirSVR_highEffct hsa-miR-877*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.26E-29 1.77E-25 2.54E-28 2.33E-27 72 1096 "LOC100128239,SYT9,TOMM40L,GPR158,TESK2,LRRTM4,MOG,ANK1,ANK3,PPFIA1,BCO1,RUFY2,YPEL4,SPHKAP,CAPRIN2,RCOR3,MEGF11,MYT1L,ARPP21,FGF17,NELL1,GJB1,ADHFE1,ARHGEF7,CASTOR3,PCDH11X,ZNF638,NODAL,ADGRL3,CACNA1E,PRLHR,TCF7L2,ZEB1,PTBP2,VSTM2A,GRIA1,GRIA2,GRIK2,LINC00839,TGFBR3,CELF3,TNS1,PCDH9,RBFOX2,ZNF384,HMGB1,PFKFB3,CASC2,JAM2,SLC22A6,NRXN2,CAMKV,NMT2,CHD1L,PMEPA1,BDNF-AS,PRDM2,BLOC1S6,ZC3H11A,KCNA4,CDH20,SMG7,KCNK2,PCDH15,RALGDS,PAK5,FAM135B,ABI2,SLC4A10,ELAVL3,ELAVL4,BSCL2" MicroRNA hsa-miR-223:mirSVR_highEffct hsa-miR-223:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.49E-29 1.89E-25 2.72E-28 2.49E-27 68 974 "ACER3,ARID1A,F3,DSCAML1,KLRC4,FABP7,GRAMD1B,FCGR1A,FCGR1B,GPR158,SCN3A,FHL1,FOXG1,SOX6,ASRGL1,USP28,PKP4,APC,SORBS1,API5,CLSTN1,USP16,ZNF365,MSR1,CSPG5,CAPRIN2,ASPH,SORCS3,CAB39,RAP1GAP2,PCDH11X,UNC5D,ANO4,PTBP2,GRIA4,CCKBR,TMEM25,TGFBR3,AIFM1,MAEL,PAX6,C1orf94,LGI1,MAGI1,SCRG1,A2ML1,CELF5,P2RY12,PPP2R5C,PPP3CB,RGS6,FEZ2,RBPJ,PKN2,PLD5,CTNND1,TOX,ANKS1B,KCNC1,KCNJ9,RABGAP1L,PYGM,TMEM255A,FAM13C,ABCC9,ABI2,YY1AP1,C2orf80" MicroRNA hsa-miR-324-5p:mirSVR_lowEffct hsa-miR-324-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.93E-29 2.13E-25 3.05E-28 2.80E-27 71 1068 "RABEPK,ASIC1,ARID1A,ADORA3,AMER2,HOGA1,PLA2G6,MOBP,ANK3,DOCK10,GPAM,SFMBT2,MSRA,NRG3,WDTC1,SOX1,LHFPL4,TTLL9,NAP1L2,FXYD6,ALDH1L1,GJB1,GANAB,MLC1,PCDH11X,KAZN,SEMA4A,GNAS,GNG4,ANO4,TCF7L2,ZEB1,CECR2,USP2,MFSD2A,FBXL16,P2RX7,TJP1,ZFP91,REPS2,PDE1A,NLGN3,PIK3CD,CELF5,BEST1,IFFO1,POU3F2,SNCAIP,NKAIN4,NCAN,RBPJ,PRKAB2,USP54,NRSN1,FAM131B,KIAA0408,WBP1L,GON4L,SIRPA,PRDM2,SRGAP3,KCNJ4,KLRC2,PID1,SLC25A48,PARP11,DTNA,ABCC9,ZYG11B,RFX4,FGFBP3" MicroRNA hsa-miR-3166:mirSVR_highEffct hsa-miR-3166:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.68E-29 2.53E-25 3.63E-28 3.33E-27 66 919 "CNTNAP3,MEG3,ADGRV1,EYA1,CSMD2,WAC,FABP7,KIAA1109,FHL1,APBB1,NTNG1,API5,SHTN1,ZNF365,MIER1,SLC8A3,SORCS3,ATP2B2,GABBR1,MYT1L,B3GALT2,TNIK,CADM3,AHCYL1,ARPP21,KIF1B,ERBIN,ARHGEF7,GLS,POPDC3,DCLK2,CAMTA1,UNC5D,ZEB1,CCKBR,CRB1,MAEL,CDH10,PDE4B,MS4A7,SULT4A1,ACBD5,RNF14,PPP2R5C,SNCAIP,OSBPL3,ATRNL1,DOCK7,PRKCZ,IGSF1,ZBTB16,CA10,BDNF-AS,PTHLH,DLG3,WIPF2,DSCAM,DTNA,SLC6A15,ZYG11B,CAMK1G,RFX4,RGS7,ATL1,SEC61A2,EN2" MicroRNA hsa-miR-500b:mirSVR_lowEffct hsa-miR-500b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.98E-29 2.70E-25 3.86E-28 3.54E-27 87 1609 "PRR5L,CNTNAP3,SYT9,RTN3,MEG3,MRVI1,CSMD2,GALNT13,FABP7,FGF1,TRIM46,PPFIA1,SESN3,DGKZ,SORBS1,CACHD1,SHTN1,URGCP,PKNOX2,ARFGAP2,SMARCE1,TMEM108,ATM,EIF4G3,PHYHIPL,DKK3,ENKUR,IDI2-AS1,DNER,SPART,GJB1,ADHFE1,GLS,ZNF638,KAZN,CAMTA1,CAMSAP2,UNC5D,CLEC9A,EML4,CAMK2A,VSTM2A,GRIA2,GRIA4,GRIK2,CRB1,INA,MAEL,MAGI1,IGFN1,PRMT8,FNDC5,HPSE2,CHGA,CASC2,MS4A7,CADM1,ZFYVE9,PMP2,PRRX1,SPATA6,FAT3,NXPH1,PPP3CB,ATRNL1,RBPJ,NOS1AP,FGFR1OP2,ANKS1B,ZNF385B,DNAJC6,PTPRZ1,NTM,KCNK1,FAM66C,FAM13C,DTNA,RET,USH1C,RFX5,ZNF248,VANGL2,EFNA3,RBM12,ABI2,TMEM100,RCAN2" MicroRNA hsa-miR-124*:mirSVR_lowEffct hsa-miR-124*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.37E-29 2.91E-25 4.16E-28 3.81E-27 90 1719 "ASIC1,LGR4,EYA1,LDLRAD3,SLC25A25,KLHL32,ADCY2,GALNT13,SORCS1,FCGR1A,CHST15,BBOX1,SOX6,AMPH,CDC42BPA,ANK3,ITSN1,TACC2,BCAS1,API5,AQP4,RPH3A,BCO1,PDE8B,CSPG5,SLCO1A2,CAPRIN2,PHYHIPL,WDTC1,GAD2,B4GALNT1,KIF1B,SEPT3,VAMP1,UNC5D,PSRC1,WWC1,KLHL4,CAMK2A,VXN,GRIA2,GRIA4,GRIK2,TF,OLR1,TMEM25,TGFBR3,ZFP91,MAEL,HPS5,CDH10,PTGDR2,LGI1,TPD52,MAGI1,TLX1,GDAP1L1,NEGR1,CRMP1,RNF14,ATRNL1,CHD5,DZIP3,PLD5,KIAA0408,BRINP3,TOX,KIAA0513,PTCH1,PMEPA1,PTHLH,PRDM2,LRP8,KCNA1,KCNJ10,KCNK1,KCNN3,NKAIN1,RFX4,FAM135B,SSPN,PIANP,SH3GLB1,RPRD1A,VWA5A,SLC4A10,EN2,OLIG2,EPB41L1,BAALC" MicroRNA hsa-miR-137:PITA hsa-miR-137:PITA_TOP PITA 5.40E-29 2.92E-25 4.17E-28 3.83E-27 51 518 "SYNDIG1,NLGN4X,UNC79,SOX6,PPM1E,ST3GAL3,SLC6A9,ARHGAP5,CADPS,MEGF11,AHCYL1,NFASC,GPR162,ERBIN,RCOR2,NEUROD1,SEPT3,ARHGEF7,GLS,LUZP2,ACSL6,CACNB2,TCF12,GPR26,GPR88,PTPN5,TJP1,DCLK1,FNDC5,HAPLN2,FAT3,MED1,PNKD,RGS6,RIMS4,PKN2,WBP1L,RIMS3,ZC3H11A,KCNA1,KCNA2,SV2A,SRGAP3,NKAIN1,SLC17A6,SLC6A15,EFNA3,RBM12,RAVER2,ELAVL3,RCAN2" MicroRNA hsa-miR-1825:mirSVR_lowEffct hsa-miR-1825:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.49E-29 3.52E-25 5.00E-28 4.59E-27 83 1474 "ZFYVE27,MDM4,KCNIP2,CLIP1,PLEKHG5,KLHL32,ADCY2,ADD3,ADORA1,FCGR1A,HOGA1,TESK2,KIAA1109,LRRC7,SOX6,TRIM46,ASRGL1,ANK3,PPFIA1,DGKZ,GPAM,SORBS1,PAAF1,MIER1,BRINP2,RCOR3,TMEM108,USP33,JPH4,EMC1,IDI2-AS1,DNER,STOX1,INKA2,NELL1,NEUROD1,ACSBG1,ABCC8,SYT4,MMD2,DDR1,ZEB1,HAP1,CAMK2A,SYT6,CRB1,USP2,TMEM9,CDH8,PDE2A,IGFN1,PDYN,FNDC5,BEST3,PIK3CD,UBTF,CPT1C,OPALIN,SULT4A1,C11orf49,IFFO1,KIAA1755,PRKCZ,NRSN1,GON4L,SPIRE1,PTHLH,CADM2,PRDM2,MAGI2,OCIAD1,PLPPR4,TMCC2,PLEKHB2,C12orf4,GOPC,FAM13C,SFXN5,SIDT2,ARHGAP12,C2orf80,TMEM100,BAALC" MicroRNA hsa-miR-3180-5p:mirSVR_highEffct hsa-miR-3180-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-29 3.52E-25 5.00E-28 4.59E-27 83 1474 "RABEPK,ABAT,ACER3,PAQR6,MEG3,ADCY2,SLITRK1,WAC,TOMM40L,KIAA1109,SOX6,ASRGL1,PKP4,CACHD1,ST3GAL3,USP16,ZNF365,CCDC88A,NAXD,SMARCE1,DKK3,SON,C11orf87,ERBIN,GNAS,DDHD2,KLHL4,ANO4,GPM6B,CACNB2,SYT6,VSTM2A,NUCB1,GRIA2,OLR1,OMG,CRB1,TLL2,TMEM257,PADI2,PDE4B,ANO5,CASC2,HNRNPK,JAM2,NRXN1,NEGR1,UBTF,SLC25A27,NXPH1,CP,POU3F2,PPP3CB,RGS6,ATRNL1,DOCK7,RAB39A,SLC45A1,KIAA0408,KIAA0513,TOMM20,PSMD13,PLPPR1,BDNF-AS,CEP170,CSDE1,KCNA2,CCDC3,KCNK1,KCNK2,KIF2A,DPP6,SUSD4,DTNA,PAK5,SLC6A15,RFX4,ZNF248,TTLL7,SEC61A2,ABI2,FGFBP3,BAALC" MicroRNA hsa-miR-577:PITA hsa-miR-577:PITA_TOP PITA 6.86E-29 3.72E-25 5.28E-28 4.84E-27 57 672 "EPS8,LGR4,EYA1,CSMD2,CLIP1,WAC,LRRC7,SOX6,ANK3,ITSN1,SH3GL2,PPM1E,APC,SLC6A9,YPEL4,DACH2,ATM,ATP2B2,SOX5,SOX10,GAD2,AHCYL1,DNER,LMO3,SYT4,UNC5D,WWC1,ZEB1,TMEM257,REPS2,PCDH8,MAGI1,HMGB1,CHGA,HNRNPK,CADM1,NRXN1,NEGR1,MEAF6,MED1,SF1,ATRNL1,USP54,NRSN1,LRRTM3,DNAJC6,CADM2,CSDE1,PTPRD,SMG7,PTPRO,SNX27,WIPF2,RGS7,SFXN5,RBM12,TMEM100" MicroRNA hsa-miR-4306:mirSVR_highEffct hsa-miR-4306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.12E-29 3.86E-25 5.47E-28 5.02E-27 74 1174 "ATAT1,ARID1A,WLS,MDM4,SLITRK1,ASIC4,FGR,MOG,USP28,MIER1,MSRA,SORCS3,SNAP25,ATP1A3,SOX5,CADM3,AHCYL1,ADGRB2,CLASP2,NDUFA5,SMOC1,INKA2,PHLDB1,GLS,ZNF638,ASTN2,GOLGB1,PRUNE2,TCF12,PTBP2,VXN,GRIA2,GRIA4,USP2,TJP1,TMEM257,MAEL,CDC42,TNR,PCDH9,PTGDR2,LGI1,TPM3,ZNF384,ACOT7,CASC2,CCSER2,BEST1,SLC36A4,SF1,PPP2R5C,OSBPL3,NCAN,PRKACB,CTNND1,NRSN1,PSMD13,CA10,HP1BP3,ZC3H11A,SMG7,PTPRE,NAV2,KCNN3,FAM66C,PARP11,DTNA,ABCC9,CAMK1G,FAM135B,INSYN2,RPRD1A,GPR61,EPB41L1" MicroRNA hsa-miR-129-3p:mirSVR_lowEffct hsa-miR-129-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.31E-29 3.96E-25 5.61E-28 5.14E-27 71 1079 "SDE2,SYT9,ATAT1,ADCY2,TOMM40L,ANK3,PPFIA1,PKP4,SHTN1,PAAF1,AQP4,ZNF365,MSR1,ARFGAP2,SLC14A1,SPHKAP,SLN,MTR,SCN3B,WDTC1,SOX5,SOX10,AHCYL1,NMNAT2,B4GALNT1,NEK6,TTLL9,BCL2L2,PHLDB1,SEPT3,ACSBG1,VAMP1,MYRF,KLHL4,GPM6B,CACNB2,TCF7L2,NUMA1,GRIA4,CYB561A3,SHISA7,CCKBR,LEFTY2,TGFBR3,PDE3B,FNDC5,HMGB1,CADM1,SEMA5B,MED1,SF1,FEZ1,OSBPL3,CTNND2,PSD,RIMS3,PTPRO,PEX5,DLG2,C12orf4,GNE,BSDC1,ABCC9,CAMK1G,NUP214,RFX4,PHC2,VANGL2,RLBP1,SIDT2,GPR61" MicroRNA hsa-miR-96:mirSVR_highEffct hsa-miR-96:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.69E-29 4.17E-25 5.89E-28 5.40E-27 66 927 "ABAT,KLHL32,ADD3,LRRC7,FHL1,SOX6,TRIM46,MAGI3,SYBU,SLC6A9,TAGLN3,BRINP2,RCOR3,FYN,SOX5,SOX10,GAD2,B4GALNT1,KIF1B,CLASP2,ADHFE1,AJAP1,ARHGEF7,GLS,PCDH11X,TBX15,GPM6A,GPM6B,CACNA1E,LILRA1,TCF7L2,ZEB1,GRIA1,GRID1,RFFL,TF,CCKBR,PCDH9,LGI1,MAGI1,PDE1A,ZMYND8,ANO5,PFKFB3,ANLN,OPALIN,PRRX1,MED1,CRLS1,DOCK7,CTNND1,ECE2,HP1BP3,ZC3H11A,PLPPR4,AK5,KCNK2,DLG2,DSCAM,GNE,BSDC1,JMJD1C,LPAR6,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-1228:mirSVR_lowEffct hsa-miR-1228:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.70E-29 4.17E-25 5.89E-28 5.40E-27 87 1619 "DPF1,ABAT,ZFYVE27,ACER3,PAQR6,MRVI1,CSMD2,KLHL32,GRAMD1B,CHST15,FOXM1,AMPH,SGIP1,ANXA7,GPAM,JAKMIP3,ZNF365,SLC1A6,PKNOX2,MT3,CGREF1,IGSF9B,ATM,SNCB,EIF4G3,GABBR1,WDTC1,MYT1L,SOX5,AHCYL1,ADAM15,ADGRB2,NPAS3,NFASC,NDUFA5,PCDH11X,UNC5D,KLHL4,ANO4,TBX15,PRUNE2,ZEB1,TCF12,NUMA1,GRIA2,GRID1,CYB561A3,CRB1,P2RX7,TIE1,PCSK2,PDE2A,PIRT,GPR37L1,TLX1,CAMKV,OPALIN,TJP2,FTO,SULT4A1,NSD2,POU3F2,FMN2,NRSN1,MAPK10,NOS1AP,FGFR1OP2,MASP1,TOX,ANKS1B,GON4L,TUBB2B,DNAJC6,HP1BP3,PTPRD,SMG7,SRGAP3,KCNJ9,KCNJ11,PCDH15,WIPF2,RAD52,DPP6,DTNA,ABCC9,CAMK1G,RBM12" MicroRNA hsa-miR-144*:mirSVR_highEffct hsa-miR-144*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.29E-29 4.49E-25 6.33E-28 5.81E-27 70 1050 "MBP,LGR4,ADGRV1,MDM4,SLITRK1,NLGN4X,SLC44A5,LRRC7,BBOX1,GOLGA7B,CDC42BPA,APBB1,CCDC88A,MTR,SMARCE1,RCOR3,NRG3,SON,MYT1L,ENKUR,ARPP21,CLASP2,PCDH11X,SYT4,UNC5D,PTBP2,EML4,GRIA2,GPR88,CRB1,PCDH8,PCSK2,ZMYND8,FNDC5,MS4A7,TMEFF2,SEMA5B,CCSER2,BTF3L4,SPATA6,NSD2,CP,SF1,SNCAIP,PPP3CB,KCNT2,PRKACB,NRSN1,ANKS1B,ZNF385B,LRRTM3,ITGAV,HP1BP3,MAGI2,OCIAD1,DLG2,RAB5B,PID1,SLC25A48,SLC17A6,PARP11,DTNA,SLC6A15,ZYG11B,RET,RFX5,FAM135B,ZNF248,PIANP,SH3GLB1" MicroRNA hsa-miR-125b-2*:mirSVR_highEffct hsa-miR-125b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-29 4.53E-25 6.39E-28 5.86E-27 72 1113 "CNTNAP3,CLIP1,RTN1,SORCS1,ERMN,NLGN4X,KIAA1109,FGF1,HPCAL4,SGIP1,CDC42BPA,ITSN1,ZCCHC17,ST3GAL3,MSR1,SPHKAP,DLL3,ASPH,TNIK,ZCCHC24,GAD2,NPAS3,NCAM1,C11orf87,ERBIN,ACSBG1,GPM6A,GPM6B,PTBP2,EML4,NUMA1,GRID1,CRB1,USP2,TMEM257,HPS5,PCDH8,PCDH9,SEZ6L,PDE3B,MS4A7,TMEFF2,TLX1,CADM1,OPALIN,SLC36A4,MED1,CRMP1,CRLS1,RGS6,ATRNL1,RBPJ,DOCK7,DZIP3,USP54,NRSN1,EDRF1,ZNF385B,LRRTM3,ITGAV,CA10,PLPPR1,CADM2,PRDM2,CEP170,PTPRO,SLC17A6,FAM13C,FAM135B,PHC2,RAVER2,SLC4A10" MicroRNA hsa-miR-450b-5p:PITA hsa-miR-450b-5p:PITA_TOP PITA 9.21E-29 4.99E-25 7.01E-28 6.43E-27 54 598 "GPR158,FOXG1,ANK3,ITSN1,SESN3,ARHGAP5,SPHKAP,RCOR3,PALLD,MYT1L,B3GALT2,CAB39,NELL1,RHBDL3,CAMTA1,ADGRL3,GPM6A,EML4,ADAMTS8,TJP1,TMEM257,PADI2,PCDH8,CDH10,LGI1,PCSK2,ZNF384,PDE4B,HMGB1,TUB,HNRNPK,CADM1,KIAA1549L,VAV2,CELF5,FAT3,TENM4,PPP3CB,CTNND1,WBP1L,SIRPA,PMEPA1,KCNA1,PTPRZ1,KCNK2,DLG3,TMEM255A,SLC17A6,RTN4,PAK5,FAM135B,INSYN2,ARHGAP12,OLIG2" MicroRNA hsa-miR-567:mirSVR_lowEffct hsa-miR-567:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.63E-29 5.21E-25 7.32E-28 6.72E-27 90 1733 "RABEPK,EPS8,C1orf194,ACER3,MEG3,IL17D,F3,KLHL32,ADD3,SLC44A5,GPR158,SCN4B,LRRTM4,BCAR3,ERICH3,ANK2,ANXA7,DOCK10,ZNF365,MSRA,SLC14A1,SCG3,SORCS3,TMEM108,ATM,DKK3,B3GALT2,CAB39,GAD2,JPH4,KIF1B,NAP1L2,NPAS3,SPART,C11orf87,CLASP2,NELL1,RGL1,SLCO1C1,DCLK2,ANO4,ACSL6,DIRAS1,NUDT21,CAMK2G,GRIA1,TMEM25,LEFTY2,GUCY1A2,TPM3,PDE1A,PDYN,ZMYND8,TUB,PMP2,MEAF6,SLC25A27,NSD2,CP,CRLS1,PPP2R5C,PPP3CB,PRKAB2,BRINP3,SPIRE1,PLPPR5,ZNF385B,JAKMIP2,BDNF-AS,PTHLH,PRDM2,HP1BP3,LRP8,CEP170,CSDE1,BLOC1S6,OLFM3,KCNJ10,KCNMA1,NAV2,SLC17A6,ATG16L1,PAK5,BSDC1,RGS10,VANGL2,SLC39A12,RPRD1A,ABI2,ELAVL4" MicroRNA hsa-miR-488:mirSVR_highEffct hsa-miR-488:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.05E-28 5.70E-25 7.99E-28 7.33E-27 79 1347 "TTYH1,PRR5L,SYT9,LGR4,ATAT1,CSMD3,ADARB2,CDC7,FABP7,SORCS1,ERMN,GPR158,LINC00461,LRRC7,ANK3,PPFIA1,ANXA7,APBA2,SESN3,TACC2,AQP4,SLC14A1,CADPS,TMEM249,TAGLN3,DKK3,MYT1L,SOX5,NEK6,NPAS3,ERBIN,RGL1,GANAB,SLCO1C1,ARHGEF7,POPDC3,CAMTA1,CAMSAP2,GOLGB1,WWC1,ANO4,PTBP2,NUMA1,GPR88,CRB1,INA,GUCY1A2,ZFP91,CDC42,PCDH9,LGI1,PDE1C,PDYN,HMGB1,PFKFB3,CHRM1,HEPACAM,CADM1,MEAF6,POU3F4,MED1,PPP2R5C,PPP3CB,PHACTR3,PLD5,ANKS1B,SYNC,LRRTM3,BDNF-AS,CEP170,PTPRE,KCNJ10,SNX27,CAB39L,RFX4,RGS7,PIANP,RERGL,RAVER2" MicroRNA hsa-miR-4280:mirSVR_lowEffct hsa-miR-4280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-28 5.98E-25 8.37E-28 7.68E-27 79 1348 "RABEPK,RCSD1,ACTN2,MEG3,WLS,ADAR,KLHL32,RXRG,GALNT13,GRAMD1B,NLGN4X,TOMM40L,FHL1,UNC79,AMPH,ANK2,PPM1E,APC,GPAM,API5,AQP4,ZNF365,MSR1,SLCO1A2,NRG3,MEGF11,USP33,MYT1L,SOX5,NMNAT2,NAP1L2,C11orf87,CLASP2,SEMA4A,TMEM136,ANO4,CACNA1E,DDR1,TMEM151B,VXN,DDR2,VSTM2A,GRIA4,ATP13A2,OMG,OPCML,TMEM25,SEZ6L,LRTM2,CASC2,TMEFF2,P2RY12,SLC36A4,NSD2,FAT3,CP,VCAN,NCAN,PRKAB2,DOCK7,PLD5,ZBTB16,PLPPR5,PTCH1,LRP8,MAGI2,OLFM3,PTPRD,PTPRE,ARNT2,DLG3,NKAIN1,KIF2A,KLRC2,PARP11,SLC25A18,ABI2,VWA5A,RCAN2" MicroRNA hsa-miR-876-3p:mirSVR_lowEffct hsa-miR-876-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-28 6.03E-25 8.43E-28 7.73E-27 75 1215 "PRR5L,ACER3,CNTNAP3,SYT9,F3,KLHL32,RTN1,SCNN1D,RPH3A,MT3,SLCO1A2,NAXD,SMARCE1,RCOR3,ATP1A2,DKK3,SON,WDTC1,SOX1,B3GALT2,ZSWIM8,KIF1B,ADGRB2,STOX1,NELL1,PHLDB1,NEUROD1,SEPT3,VAMP1,WWC1,CAMK2A,CECR2,VXN,SYT6,VSTM2A,GRIA1,CRB1,TMEM9,GUCY1A1,REPS2,CDC42,CDH8,FNDC5,LRTM2,KIAA1549L,CNTN1,MEAF6,MED1,TENM4,RGS6,OSBPL3,ATRNL1,ARHGEF4,NRSN1,ECE2,PROX1,TOX,KIAA0513,PLPPR1,CADM2,SRGAP3,AK5,KCNMA1,NAV2,SNX27,SLC25A48,ATN1,DBX2,ZYG11B,VANGL2,SH3GLB1,ABI2,ROM1,EPB41L2,UEVLD" MicroRNA hsa-miR-361-5p:mirSVR_lowEffct hsa-miR-361-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-28 6.67E-25 9.31E-28 8.54E-27 88 1666 "MAPT,ACLY,TMEM74,MBP,DUSP27,ARID1A,CSMD3,ADCY2,WAC,LRRTM4,GOLGA7B,UNC79,MOBP,CDC42BPA,PPM1E,SORBS1,NLGN1,MSR1,PKNOX2,CSPG5,ASPH,ASTN1,SMARCE1,SNAP25,PHYHIPL,SOX5,ENKUR,IDI2-AS1,DNER,C11orf87,AJAP1,SLCO1C1,NHLH1,ROBO3,PRUNE2,ACSL6,CACNA1E,HAP1,AZIN2,VXN,VSTM2A,BRSK2,GRID1,OMG,TGFBR3,INA,P2RX7,AIFM1,MAEL,CDC42,C1orf94,TPD52,PDE3B,CIART,KIAA1549L,FADS2,MEAF6,NSD2,NXPH1,ACBD5,CNRIP1,CSF3R,PRKCZ,IGSF1,PUM1,KIAA0408,TOX,DPYSL5,PTCH1,JAKMIP2,BDNF-AS,KCNA1,PTPRE,PLPPR4,PTPRO,SV2A,KCNJ10,NAV2,SNX27,DLG2,PLEKHB2,RET,ZNF248,SH3GLB1,RPRD1A,ELAVL3,RPE65,EPB41" MicroRNA hsa-miR-4278:mirSVR_lowEffct hsa-miR-4278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-28 7.98E-25 1.11E-27 1.02E-26 61 792 "TTYH1,ABAT,ACHE,RYR1,ERMN,CHST15,SNX32,TESK2,UNC79,SOX6,SFPQ,SGIP1,PPFIA1,DGKZ,BCAN,JAKMIP3,SLC14A1,SLCO1A2,ATP2B2,MEGF11,GAD2,ZSWIM8,ADAM15,SPART,GLS,KAZN,GNAS,MYRF,GRM3,FBXL16,CELF3,TMEM257,ZDHHC22,PCDH8,CHGA,CASC2,HNRNPK,ZFYVE9,UBTF,NSD2,PTPA,SNCAIP,TENM4,ATRNL1,SDC3,NOS1AP,MASP1,PTHLH,COPS7A,SMG7,KCNH1,SRGAP3,KCNJ10,RAB5B,FAM57B,GNE,FAM13C,ZYG11B,PHC2,CBLN2,RAVER2" MicroRNA hsa-miR-1233:mirSVR_lowEffct hsa-miR-1233:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.54E-28 8.34E-25 1.16E-27 1.07E-26 80 1389 "ZFYVE27,KCNIP2,SORCS1,FCGR1A,TESK2,LRRTM4,LINC00461,ELMOD1,PDZD4,SOX6,DOCK10,NTNG1,BCAN,PAAF1,ZNF365,KIAA1614,MADD,LRRC55,DACH2,GPR153,ARFGAP1,ASPH,B3GAT1,DKK3,SCN3B,WDTC1,KIF21B,AHCYL1,TTLL9,FXYD6,NFASC,C11orf87,GPR162,RCOR2,NODAL,CAMSAP2,UNC5D,BTRC,TMEM136,HAP1,PCDHGA3,AKNA,GRIK4,TMEM257,ZFP91,TNR,PCDH9,IGFN1,NMT2,TJP2,NSD2,CHD1L,SNCAIP,MICAL2,VCAN,PRKCZ,CTNND2,MAPK10,EDRF1,FAM131B,PSD,DPYSL5,ANKS1B,GON4L,KCNA6,PTPRE,NTM,KCNJ11,CCDC3,PEX5,RAB3IL1,KLRC2,PARP11,RASGRF1,RET,PHC2,RNF220,SH3GLB1,VWA5A,BAALC" MicroRNA hsa-miR-4277:mirSVR_highEffct hsa-miR-4277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-28 8.38E-25 1.17E-27 1.07E-26 79 1355 "ARID1A,ADD3,WAC,ERMN,FCGR1A,ELMOD1,FOXG1,SGIP1,CDC42BPA,ITSN1,GPAM,SORBS1,CCDC88A,CGREF1,ASPH,SMARCE1,SON,B3GALT2,ENKUR,GART,DNER,FXYD6,SPART,NCAM1,NDUFA5,ACSBG1,SYT4,SEMA4A,DDHD2,UNC5D,PRUNE2,ACSL6,ZEB1,GPR17,GRIA4,GRID1,LEFTY2,PDE3B,PDYN,NTSR2,CASC2,HNRNPK,DLGAP3,CNTN1,P2RY12,CHD1L,MED1,RNF14,PTPA,PRKAB2,PKN2,PLD5,NRSN1,MASP1,LRRTM3,MAGI2,OCIAD1,PTPRD,RABGAP1L,KCNK1,PCDH15,KCNMA1,PEX5,KIF2A,PARP11,SUSD4,ABI1,DBX2,DTNA,RFX4,RGS7,SEC61A2,SSPN,SH3GLB1,RPRD1A,FGFBP3,SLC4A10,EPB41L1,BAALC" MicroRNA hsa-miR-330-3p:TargetScan hsa-miR-330-3p TargetScan 1.55E-28 8.40E-25 1.17E-27 1.07E-26 59 737 "EPS8,RIMKLA,RCSD1,KCNIP2,KLHL32,ADCYAP1R1,ADD3,HPCAL4,CDC42BPA,PPM1E,APC,GPAM,KIAA1614,SCG3,NRG3,ATP2B2,DKK3,SCN3B,CADM3,KIF1B,NFIA,GLS,MYRF,BTRC,PRUNE2,GPM6A,ACSL6,PSD3,GRID1,CELF3,PDE3B,HPSE2,PFKFB3,HNRNPK,JAM2,PRRX1,ACBD5,PRKAB2,MAPK10,NOS1AP,PROX1,RIMS3,DPYSL5,JAKMIP2,ELMO1,PRTFDC1,LRP8,CEP170,OCIAD1,KCNH1,RABGAP1L,NKAIN1,PARP11,L1CAM,PHC2,EFNA3,RBM12,RAVER2,RCAN2" MicroRNA hsa-miR-103-as:mirSVR_lowEffct hsa-miR-103-as:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-28 8.50E-25 1.18E-27 1.08E-26 74 1189 "CNTNAP3,CSMD3,NDRG2,GALNT13,HOGA1,KIAA1109,UNC79,SOX6,CDC42BPA,ANK1,ANK3,USP28,PPFIA1,PKP4,APC,API5,BCO1,MSRA,CCDC88A,SLC14A1,DLL3,CAPRIN2,PALLD,SON,SOX5,ZSWIM8,IDI2-AS1,SPART,NFASC,NCAM1,LUZP2,DCLK2,GNAS,UNC5D,TMEM136,PRUNE2,GPM6B,ATF7,DDR1,ZEB1,CAMK2A,CAMK2G,VSTM2A,AKNA,GRIA1,OLR1,OPCML,LINC00839,INA,CELF3,TMEM257,CDH10,TPM3,PDE2A,HMGB1,JAM2,GDAP1L1,ST8SIA5,PLXNB3,MICAL2,ATRNL1,FMN2,CTNND1,FGFR1OP2,TOMM20,SRGAP3,SNX27,WIPF2,DSCAM,ABCC9,ZYG11B,RFX4,ZNF248,SYT15" MicroRNA hsa-miR-10b*:mirSVR_highEffct hsa-miR-10b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.59E-28 8.62E-25 1.19E-27 1.10E-26 71 1093 "ADAR,KLHL32,SORCS1,ADORA3,MOBP,ANK1,SESN3,NTNG1,ST3GAL3,API5,SHTN1,MSR1,NAXD,NRG3,TNIK,CAB39,NMNAT2,ARPP21,ADGRB2,NASP,LMO3,C11orf87,NEUROD1,PCDH11X,ZNF638,GNAS,MMD2,ANO4,TBX15,WSCD1,VXN,GRIA2,PAH,TNS1,TPD52,ZMYND8,BEST3,NLGN3,NRXN1,CCSER2,IFFO1,CHD1L,SNCAIP,RBPJ,DOCK7,PRKCG,PUM1,MASP1,SYTL2,GON4L,DNAJC6,ITGAV,MAGI2,KCNA1,KCNA4,OCIAD1,PLPPR4,PCDH15,CAB39L,PAK5,SLC6A15,ZYG11B,JMJD1C,FAM135B,INSYN2,PHC2,ZNF248,TTLL7,SEC61A2,RPRD1A,SLC4A10" MicroRNA hsa-miR-223*:mirSVR_highEffct hsa-miR-223*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-28 9.10E-25 1.26E-27 1.16E-26 76 1256 "RCSD1,EYA1,WLS,GALNT13,PNMA8B,HOGA1,KIAA1109,FGF1,ERICH3,PPFIA1,ITSN1,GPAM,LRRC4C,MIER1,ARHGAP5,SPHKAP,SMARCE1,RCOR3,NRG3,EIF4G3,PALLD,MYT1L,NEUROD1,RND1,AJAP1,DDHD2,CAMSAP2,ANO4,TBX15,GPM6A,GPM6B,CLEC9A,CECR2,VXN,TJP1,LGI1,TPM3,TPM4,PDE1A,ANO5,LRTM2,JAM2,GDAP1L1,ANLN,NMT2,PMP2,PMS2,SPATA6,P2RY12,NSD2,FAT3,NXPH1,POU3F2,PPP2R5C,KCNT2,OSBPL3,VCAN,RBPJ,DZIP3,CTNND2,TOMM20,SYNC,BDNF-AS,PTHLH,CNIH3,OLFM3,SMG7,SNX27,DLG2,KLRC2,PID1,TMEM255A,C12orf4,SLC6A15,ABI2,RCAN2" MicroRNA hsa-miR-1303:mirSVR_lowEffct hsa-miR-1303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-28 9.47E-25 1.31E-27 1.20E-26 93 1859 "MAG,ADGRV1,EYA1,ATAT1,SLITRK1,GRAMD1B,LRRC7,UNC79,ELMOD1,SOX6,FOXM1,ERICH3,PPFIA1,ANXA7,APBA2,DOCK10,SESN3,GAS7,SORBS1,RPH3A,SHANK2,DACH2,GPR153,SCG3,ASPH,SORCS3,FYN,SCN3B,KIF21B,ENKUR,KIF1B,ADGRB2,RAP1GAP2,SEPT3,ARHGEF7,PCDH11X,ASTN2,ADGRL3,PRUNE2,ACSL6,LRIT2,LILRA1,PCDHGA3,VSTM2A,GRIK2,OPCML,LINC00839,CRB1,TLL2,ATG4C,PADI2,DCLK1,PCSK2,ZNF384,GDAP1L1,KIAA1549L,NEGR1,CCSER2,DNAJC12,FLRT1,FTO,MEAF6,P2RY12,ATCAY,PPP2R5C,PLD5,GON4L,PSMD13,PTHLH,KCNA1,PTPRD,PLPPR4,KCNJ9,ARNT2,PYGM,DLG3,NKAIN1,KLRC3,SLC17A6,FAM66C,GOPC,BSDC1,ABCC9,SLC6A15,ZYG11B,NUP214,RFX5,EFNA3,SH3GLB1,RPRD1A,OLIG2,EPB41,EPB41L1" MicroRNA hsa-miR-520h:mirSVR_highEffct hsa-miR-520h:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-28 9.62E-25 1.33E-27 1.22E-26 78 1324 "ZFYVE27,ACER3,MAP6,EYA1,ATAT1,CSMD3,F3,KLHL32,WAC,NLGN4X,HOGA1,FOXG1,ERICH3,APC,MAGI3,NLGN1,ZNF365,SORCS3,EIF4G3,ADGRB2,NPAS3,NCAM1,ZNF638,DCLK2,DDHD2,CAMSAP2,GOLGB1,GPM6B,TCF12,OLR1,PTPN5,ZFP91,PAH,MAEL,HPS5,PCDH8,ARHGAP19,TPM3,TPM4,MAGI1,ZNF384,PRMT8,HERC2P3,TLX1,ANLN,OPALIN,C11orf49,ACBD5,PPP3CB,OSBPL3,PKN2,IGSF1,CTNND2,WBP1L,LRRTM3,ITGAV,CA10,PLPPR1,PTHLH,OLFM3,KCNC1,PTPRO,PCDH15,DLG2,RAB5B,DBX2,RTN4,ABCC9,ZYG11B,RFX4,JMJD1C,RGS7,FAM135B,ATL1,SEC61A2,SLC4A10,TMEM100,EPB41L2" MicroRNA hsa-miR-599:mirSVR_highEffct hsa-miR-599:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.80E-28 9.75E-25 1.34E-27 1.23E-26 65 911 "MBP,KLHL32,RTN1,SORCS1,ERMN,TOMM40L,GPR158,LRRTM4,SLC30A10,HPCAL4,MOBP,MOG,PPFIA1,SH3GL2,LRRC4C,SORCS3,EIF4G3,CAB39,ILDR2,GAD2,ARPP21,TTLL9,CLASP2,FAM168A,ZNF638,LUZP2,UNC5D,ANO4,PRUNE2,ZEB1,TCF12,RFFL,C1orf94,MAGI1,PDE1C,PDE4B,CASC2,TMEFF2,PMP2,CNRIP1,CP,CRMP1,RBPJ,FMN2,CMTM5,USP54,MAPK10,ANKS1B,BDNF-AS,PTHLH,PRTFDC1,CEP170,KCNA2,PTPRD,RABGAP1L,KCNK2,KLRC2,FAM13C,BSDC1,CAMK1G,JMJD1C,FAM135B,TTLL7,EPB41,RCAN2" MicroRNA hsa-miR-495:PITA hsa-miR-495:PITA_TOP PITA 1.92E-28 1.04E-24 1.43E-27 1.31E-26 59 740 "LDLRAD3,ERMN,GPR158,SCN3A,FOXG1,SOX6,AMPH,SFPQ,SESN3,ARHGAP5,SPHKAP,SNAP25,EIF4G3,ATP2B2,WDTC1,MYT1L,SOX5,ZCCHC24,DNER,CLASP2,NFIA,RHBDL3,CAMTA1,CAMSAP2,BTRC,GPM6A,EML4,CAMK2A,CAMK2G,SYT6,TJP1,PCDH9,RBFOX2,ARHGAP19,TPM3,MAGI1,LRTM2,HNRNPK,CADM1,NEGR1,VAV2,BTF3L4,MED1,RIMS4,CTNND2,MAPK10,PTCH1,HP1BP3,PTPRD,PTPRE,PTPRZ1,DLG3,NKAIN1,SLC17A6,ABI1,GOPC,RTN4,RET,EPB41L2" MicroRNA hsa-miR-129*:mirSVR_lowEffct hsa-miR-129*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.98E-28 1.07E-24 1.48E-27 1.35E-26 71 1097 "SDE2,SYT9,ATAT1,ADCY2,TOMM40L,ANK3,PPFIA1,PKP4,SHTN1,PAAF1,AQP4,ZNF365,MSR1,ARFGAP2,SLC14A1,SPHKAP,SLN,MTR,SCN3B,WDTC1,SOX5,SOX10,AHCYL1,NMNAT2,B4GALNT1,NEK6,TTLL9,BCL2L2,DCAF5,PHLDB1,SEPT3,ACSBG1,VAMP1,MYRF,KLHL4,GPM6B,CACNB2,TCF7L2,NUMA1,GRIA4,CYB561A3,SHISA7,CCKBR,LEFTY2,TGFBR3,PDE3B,FNDC5,CADM1,SEMA5B,MED1,SF1,PPP3CB,FEZ1,OSBPL3,PSD,RIMS3,PTPRO,PEX5,DLG2,C12orf4,GNE,BSDC1,ABCC9,CAMK1G,NUP214,RFX4,PHC2,VANGL2,RLBP1,SIDT2,GPR61" MicroRNA hsa-miR-155*:mirSVR_lowEffct hsa-miR-155*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-28 1.14E-24 1.56E-27 1.43E-26 81 1430 "ACER3,MAP6,ASIC1,MBP,SYT9,MEG3,FAM43B,KCNIP2,CSMD3,ADAR,SNX30,NLGN4X,LINC00461,LRRC7,GOLGA7B,MOBP,PKP4,PPM1E,MAGI3,DGKD,PAAF1,ZNF365,LRRC55,SLC8A3,SMARCE1,RCOR3,CAB39,ARPP21,TTLL9,KIF1B,INKA2,FGF17,RGL1,SLCO1C1,NFIA,GLS,PCDH11X,GNAS,UNC5D,CNTN2,TCF12,AZIN2,CECR2,GRM3,LEFTY2,FBXL16,TJP1,AIFM1,ZDHHC22,PAH,ARHGAP19,TMPRSS5,CA14,HEPACAM,NRXN1,NSD2,CRLS1,TENM4,MICAL2,PHACTR3,RBPJ,DOCK7,PUM1,NOS1AP,KIAA0408,SPIRE1,SYNC,PTCH1,PRDM2,CEP170,OCIAD1,SMG7,PTPRZ1,SRGAP3,KCNMA1,SLC25A48,DPP6,SLC6A15,RFX5,RPRD1A,SLC4A10" MicroRNA hsa-miR-107:TargetScan hsa-miR-107 TargetScan 2.34E-28 1.27E-24 1.74E-27 1.59E-26 53 584 "ACER3,ASIC1,CLIP1,GALNT13,FOXG1,ANK1,ANK3,ITSN1,PPM1E,LRRC4C,LRRC55,ARHGAP5,PDE8B,PHYHIPL,CAB39,KIF1B,NPAS3,BCL2L2,DCAF5,NFIA,KAZN,BTRC,CNDP1,CAMK2G,CECR2,AIFM1,ARHGAP19,PDE3B,PRMT8,HMGB1,HPSE2,CHRM1,CAMKV,NMT2,PACSIN1,IFFO1,POU3F2,PPP2R5C,PRKAB2,CTNND1,MAPK8,RIMS3,JAKMIP2,KCNA2,KCNH1,NAV2,KCNN3,FAM57B,GOPC,PIANP,ABI2,ELAVL3,EN2" MicroRNA hsa-miR-103a-3p:TargetScan hsa-miR-103a-3p TargetScan 2.34E-28 1.27E-24 1.74E-27 1.59E-26 53 584 "ACER3,ASIC1,CLIP1,GALNT13,FOXG1,ANK1,ANK3,ITSN1,PPM1E,LRRC4C,LRRC55,ARHGAP5,PDE8B,PHYHIPL,CAB39,KIF1B,NPAS3,BCL2L2,DCAF5,NFIA,KAZN,BTRC,CNDP1,CAMK2G,CECR2,AIFM1,ARHGAP19,PDE3B,PRMT8,HMGB1,HPSE2,CHRM1,CAMKV,NMT2,PACSIN1,IFFO1,POU3F2,PPP2R5C,PRKAB2,CTNND1,MAPK8,RIMS3,JAKMIP2,KCNA2,KCNH1,NAV2,KCNN3,FAM57B,GOPC,PIANP,ABI2,ELAVL3,EN2" MicroRNA hsa-miR-298:mirSVR_highEffct hsa-miR-298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-28 1.29E-24 1.76E-27 1.62E-26 74 1197 "RABEPK,ACER3,SYNDIG1,ADGRV1,WLS,CSMD3,NDRG2,SLC44A5,TESK2,KIAA1109,LRRC7,FHL1,ANK2,SH3GL2,NTNG1,MAGI3,PAAF1,ZNF365,MIER1,SLC1A6,MADD,CSPG5,SORCS3,SMARCE1,RCOR3,PHYHIPL,MYBPC1,WDTC1,CAB39,C11orf87,CLASP2,RGL1,GANAB,ARHGEF7,SEMA4A,CDK5R2,TBX15,FAM69C,ZEB1,TCF12,PTBP2,AKNA,GRIA2,INA,TMEM257,REPS2,PCDH9,CDH8,PDE4B,HERC2P3,OPALIN,CNTN1,SPATA6,MED1,SF1,RGS6,MICAL2,OSBPL3,ATRNL1,PLPP4,IGSF1,CTNND1,PLPPR5,ZNF385B,LRP8,KCNA2,PLPPR4,KCNC1,CCDC3,HS3ST4,FAM66C,DTNA,RTN4,FGFBP3" MicroRNA hsa-miR-1185:mirSVR_lowEffct hsa-miR-1185:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.48E-28 1.34E-24 1.83E-27 1.68E-26 72 1133 "PRR5L,SYT9,RCSD1,SYNDIG1,KCNIP2,SLITRK1,CDC7,FOXRED2,SCN3A,SCN4B,LRRTM4,FGR,GOLGA7B,ANK2,PPFIA1,NTNG1,BCAS1,MSR1,DLL3,DDX25,NRG3,MEGF11,SCN3B,SON,AHCYL1,ARPP21,SPART,NELL1,AJAP1,PCDH11X,DDHD2,CNTN2,DDR1,VXN,GRIA2,PCDH9,CDH10,DCLK1,RBFOX2,ARHGAP19,BEST3,HMGB1,ANO5,PLEKHB1,CASC2,KIAA1549L,NEGR1,A2ML1,NXPH1,RGS6,PHACTR3,PRKACB,SDC3,NRSN1,EDRF1,HP1BP3,LRP8,SV2A,PCDH15,KCNMA1,DLG2,RAB5B,KLRC2,TMEM255A,SLC17A6,PAK5,ARHGAP12,SLC4A10,ELAVL4,EPB41L2,SEZ6,UEVLD" MicroRNA hsa-miR-3173:mirSVR_highEffct hsa-miR-3173:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.61E-28 1.41E-24 1.92E-27 1.77E-26 71 1102 "MAG,TTYH1,ABAT,ZFYVE27,EYA1,ARID1A,ADARB2,SORCS1,LINC00461,CCDC80,SHTN1,ZNF365,SLC1A7,BCO1,PKNOX2,CCDC88A,ASPH,SMARCE1,TMEM108,NRG3,GAD2,ZSWIM8,KIF1B,NDUFA5,SLCO1C1,GLS,VAMP1,PCDH11X,KAZN,GNAS,ROBO3,CDK5R2,UNC5D,CACNA1E,PTBP2,NUMA1,GRIA4,GRIK2,TGFBR3,MFSD2A,INA,TMEM9,TNR,LGI1,MAGI1,ZNF384,PRMT8,HEPACAM,CCDC136,BTF3L4,SPATA6,CNRIP1,POU3F4,VCAN,ARHGEF4,IGSF1,TOMM20,PTCH1,HP1BP3,CEP170,CCDC3,KCNMA1,PYGM,NKAIN1,WIPF2,DTNA,ZYG11B,SEC61A2,YY1AP1,RASGRP2,BAALC" MicroRNA hsa-miR-670:mirSVR_highEffct hsa-miR-670:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-28 1.47E-24 2.00E-27 1.83E-26 67 978 "MDM4,ADCY2,AMER2,FCGR1A,SCN3A,LINC00461,FGF14,SLC30A10,ASRGL1,CNIH2,PKP4,APC,MAGI3,TACC2,BCAS1,SHTN1,ZNF365,LRRC55,ASPH,MTR,RCOR3,NRG3,PHYHIPL,TNIK,TTLL9,KIF1B,NCAM1,NDUFA5,GPR162,ARHGEF7,GLS,ZNF638,GNAS,GNG4,GOLGB1,CACNA1E,CACNB2,CECR2,GRIA4,GRID1,TPM4,PRMT8,JAM2,KIAA1549L,NEGR1,CNRIP1,CP,PPP3CB,PHACTR3,PROX1,TOX,SPIRE1,PRDM2,PTPRE,NTM,KCNJ9,TMCC2,KCNK2,PCDH15,RALGDS,GNE,RFX5,FAM135B,ZNF248,SEC61A2,SSPN,SLC4A10" MicroRNA hsa-miR-519b-3p:PITA hsa-miR-519b-3p:PITA_TOP PITA 3.03E-28 1.64E-24 2.23E-27 2.04E-26 56 665 "F3,RTN1,GPR158,TESK2,SCN3A,FOXG1,SGIP1,CDC42BPA,USP28,SLITRK3,API5,SHTN1,SLC1A2,RUFY2,CCDC88A,CAPRIN2,MYT1L,B3GALT2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,CAMTA1,CAMSAP2,UNC5D,ADAMTS8,NEURL1,ZFP91,REPS2,HPS5,PDE3B,PFKFB3,TLX1,CCSER2,BTF3L4,FAT3,PNKD,CHD5,NRSN1,PSD,CA10,CSDE1,MAGI2,KCNA1,PTPRD,KCNJ10,DLG2,RAB5B,DNM2,SLC17A6,ATG16L1,GOPC,SFXN5,ARHGAP12" MicroRNA hsa-miR-519a:PITA hsa-miR-519a:PITA_TOP PITA 3.03E-28 1.64E-24 2.23E-27 2.04E-26 56 665 "F3,RTN1,GPR158,TESK2,SCN3A,FOXG1,SGIP1,CDC42BPA,USP28,SLITRK3,API5,SHTN1,SLC1A2,RUFY2,CCDC88A,CAPRIN2,MYT1L,B3GALT2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,CAMTA1,CAMSAP2,UNC5D,ADAMTS8,NEURL1,ZFP91,REPS2,HPS5,PDE3B,PFKFB3,TLX1,CCSER2,BTF3L4,FAT3,PNKD,CHD5,NRSN1,PSD,CA10,CSDE1,MAGI2,KCNA1,PTPRD,KCNJ10,DLG2,RAB5B,DNM2,SLC17A6,ATG16L1,GOPC,SFXN5,ARHGAP12" MicroRNA hsa-miR-519c-3p:PITA hsa-miR-519c-3p:PITA_TOP PITA 3.03E-28 1.64E-24 2.23E-27 2.04E-26 56 665 "F3,RTN1,GPR158,TESK2,SCN3A,FOXG1,SGIP1,CDC42BPA,USP28,SLITRK3,API5,SHTN1,SLC1A2,RUFY2,CCDC88A,CAPRIN2,MYT1L,B3GALT2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,CAMTA1,CAMSAP2,UNC5D,ADAMTS8,NEURL1,ZFP91,REPS2,HPS5,PDE3B,PFKFB3,TLX1,CCSER2,BTF3L4,FAT3,PNKD,CHD5,NRSN1,PSD,CA10,CSDE1,MAGI2,KCNA1,PTPRD,KCNJ10,DLG2,RAB5B,DNM2,SLC17A6,ATG16L1,GOPC,SFXN5,ARHGAP12" MicroRNA hsa-miR-593*:mirSVR_lowEffct hsa-miR-593*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-28 1.65E-24 2.23E-27 2.04E-26 90 1761 "ZFYVE27,ACER3,APC2,ATAT1,NDRG2,TUBB4A,LINC00461,FOXG1,CDC42BPA,ANK3,APC,SHTN1,SLC7A14,RPH3A,SLC2A5,PDE8B,LGI3,SLIT1,DLL3,ASPH,ATP1A2,DKK3,GAD2,JPH4,ARPP21,TTLL9,IDI2-AS1,ADAM15,NFASC,BCL2L2,ALDH1L1,SMOC1,NCDN,MLC1,VAMP1,RHBDL3,PCDH11X,DDHD2,BTRC,CNTN2,PRUNE2,AZIN2,PTBP2,NUDT21,PCDHGA3,GRIA1,OPCML,TMEM257,NEURL1,ZDHHC22,PADI2,CDH8,HRH3,ARHGAP19,FNDC5,GPR37L1,PLEKHB1,JAM2,ST8SIA5,CHD1L,SNCAIP,FEZ1,MICAL2,OSBPL3,PLCH2,RIMS4,PRKAB2,PLPP4,EDRF1,ZBTB16,PHYHIP,JAKMIP2,PTHLH,CNIH3,RGMA,CSDE1,KCNA6,PTPRO,SV2A,KCNJ9,PCDH15,WIPF2,DPP6,RALGDS,GNE,ZYG11B,NUP214,ARHGEF10L,SIDT2,ABI2" MicroRNA hsa-miR-26a:mirSVR_highEffct hsa-miR-26a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.06E-28 1.65E-24 2.24E-27 2.05E-26 82 1473 "SDE2,CNTNAP3,LGR4,ACTN2,RTN1,ERMN,KIAA1109,FGF14,MOG,SEMA6C,SFPQ,SGIP1,ANK1,APC,NLGN1,SHTN1,MIER1,SLC1A6,RUFY2,CCDC88A,DACH2,SLCO1A2,SORCS3,ATP1A2,PALLD,USP33,ZCCHC24,CAB39,ARPP21,NEK6,KIF1B,NPAS3,CLASP2,STOX1,GLS,VAMP1,ZNF638,SYT4,POPDC3,KLHL4,CACNB2,TCF7L2,VXN,NUMA1,GRIA4,RFFL,PCDH8,PCDH9,LGI1,PDE3B,LINC01102,BEST3,PFKFB3,MS4A7,NRXN1,TJP2,PMP2,CELF5,ACBD5,CRLS1,PPP2R5C,PPP3CB,KCNT2,DZIP3,CTNND2,MAPK10,ANKS1B,TUBB2B,JAKMIP2,PTPRD,PLPPR4,KCNK1,DLG2,OLIG1,TMEM255A,RALGDS,DTNA,SLC6A15,ZYG11B,JMJD1C,VANGL2,RPRD1A" MicroRNA hsa-miR-548n:PITA hsa-miR-548n:PITA_TOP PITA 3.10E-28 1.68E-24 2.26E-27 2.08E-26 68 1011 "LGR4,RTN3,EYA1,CLIP1,RTN1,NLGN4X,SCN3A,FOXG1,SOX6,ERICH3,PPM1E,NLGN1,API5,CCDC88A,CAPRIN2,BRINP2,SMARCE1,MEGF11,SON,CAB39,LHFPL4,CLASP2,BCL2L2,RGL1,NEUROD1,VAMP1,PCDH11X,CAMTA1,CAMSAP2,GPM6A,CACNB2,TCF12,PTBP2,GRIA2,CELF3,REPS2,RBFOX2,LGI1,PDE4B,SERPINE2,NRXN1,NEGR1,MEAF6,BTF3L4,SNCAIP,TENM4,PRKACB,DZIP3,PKN2,CTNND1,PUM1,BRINP3,PTCH1,ITGAV,KCNA1,KCNK1,KCNK2,PCDH15,DLG3,KIF2A,PID1,RAD52,PARP11,ATG16L1,GNE,PAK5,SH3GLB1,ELAVL3" MicroRNA hsa-miR-4284:mirSVR_lowEffct hsa-miR-4284:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.63E-28 1.97E-24 2.65E-27 2.43E-26 92 1840 "RABEPK,TTYH1,SDE2,PRR5L,ACER3,SYT9,ADCY2,TOMM40L,HOGA1,SCN3A,ELMOD1,MOG,SEMA6C,ASRGL1,ANK3,PKP4,APBA2,GPAM,CACHD1,BCAS1,SLC7A14,KIAA1614,SFMBT2,CCDC88A,TMEM108,ATM,PALLD,USP33,SOX1,ADAM15,LMO3,COLGALT2,GFAP,NEUROD1,SEPT3,ARHGEF7,GLS,PCDH11X,LUZP2,KAZN,CAMTA1,GNG3,GOLGB1,ACSL6,PTBP2,NUDT21,EML4,CAMK2G,CRB1,P2RX7,AIFM1,REPS2,PADI2,TPM3,TPM4,MAGI1,PDE1A,PFKFB3,PLEKHB1,CASC2,MS4A7,CHRNB2,FTO,P2RY12,ATCAY,POU3F2,CHD1L,CRLS1,PPP3CB,NKAIN4,PRKACB,USP54,ECE2,FGFR1OP2,ZBTB16,SYTL2,DPYSL5,PTHLH,HP1BP3,OCIAD1,PLPPR4,C1orf109,SV2A,ARNT2,SNX27,CAB39L,PLEKHB2,GNE,PAK5,RFX4,JMJD1C,LPAR6" MicroRNA hsa-miR-155:mirSVR_lowEffct hsa-miR-155:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.78E-28 2.05E-24 2.75E-27 2.53E-26 92 1841 "TTYH1,ACER3,RTN3,MEG3,ADGRV1,F3,KLHL32,ADCY2,GALNT13,SORCS1,AMER2,NLGN4X,GPR158,HOGA1,FOXG1,ERICH3,DOCK10,SESN3,ARHGAP5,DACH2,ASTN1,FYN,KIF1B,C11orf87,SMOC1,NEUROD1,PCDH11X,ASTN2,LUZP2,NPPA,NUDT21,CECR2,GRID1,TMEM257,ZFP91,PAH,PAX6,REPS2,PCSK2,ZNF384,PDE1A,PDE3B,PDE4B,ANO5,MS4A7,TMEFF2,ZFYVE9,SEMA5B,CCSER2,NSD2,NXPH1,PPP2R5C,FEZ2,OSBPL3,ATRNL1,PRKAB2,DOCK7,RAB39A,PRKCZ,NOS1AP,ZBTB16,WBP1L,SYTL2,DPYSL5,SPIRE1,TOMM20,PLPPR5,PTHLH,CADM2,PRDM2,BLOC1S6,KCNA1,KCNA6,PTPRE,KCNC1,RABGAP1L,PCDH15,KCNN3,KIF2A,WIPF2,PID1,ABI1,DBX2,RET,PHC2,ZNF248,SEC61A2,RPRD1A,ABI2,ELAVL4,TMEM100,UEVLD" MicroRNA hsa-miR-302a*:mirSVR_highEffct hsa-miR-302a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.83E-28 2.07E-24 2.79E-27 2.56E-26 82 1478 "CDHR1,LGR4,EYA1,ARID1A,F3,CDC7,ADORA3,LRRC7,FGF14,SEMA6A,UNC79,ELMOD1,HPCAL4,MOBP,ERICH3,SGIP1,PPFIA1,SH3GL2,MAGI3,SMARCE1,RCOR3,SNAP25,CCDC181,PALLD,SON,MYT1L,B3GALT2,EMC1,DNER,SPART,NFASC,COLGALT2,ACSBG1,GLS,NKX2-2,ANO4,PRUNE2,GPM6B,CACNB2,ZEB1,PTBP2,CECR2,VSTM2A,AKNA,GRIA1,GRIA2,CDH8,PDE3B,ZMYND8,CASC2,ANLN,PIK3CD,PRRX1,IFFO1,NXPH1,RBPJ,FMN2,FGFR1OP2,WBP1L,PLPPR5,CA10,PTHLH,CADM2,HP1BP3,CEP170,CSDE1,MAGI2,OLFM3,PTPRE,KCNMA1,SNX27,OLIG1,DNM2,FAM66C,FAM13C,RTN4,RET,RBM12,LPAR6,RAVER2,OLIG2,TMEM100" MicroRNA hsa-miR-1321:mirSVR_highEffct hsa-miR-1321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.85E-28 2.08E-24 2.80E-27 2.57E-26 62 835 "ACER3,CDHR1,RTKN,ADAR,ADARB2,SORCS1,LRRTM4,KIAA1109,FGR,ITSN1,ZNF365,LRRC55,SLC6A9,CCDC88A,NSG2,TMEM108,KIF21B,ILDR2,NFASC,NCAM1,ZNF302,GNAS,ROBO3,DDR2,GRIA4,RFFL,GRIK2,CYB561A3,OMG,MAEL,TNR,C1orf94,TPM3,MAGI1,HMGB1,SLC22A6,GDAP1L1,NRXN2,DNAJC12,ST8SIA5,BTF3L4,SPATA6,NSD2,ACBD5,MED1,SNCAIP,MICAL2,OSBPL3,NCAN,RAB39A,IGSF1,GON4L,ELMO1,CEP170,KCNC1,PTPRO,KCNJ10,RAB5B,KLRC3,SLC25A48,RPRD1A,PRRT4" MicroRNA hsa-miR-513a-3p:PITA hsa-miR-513a-3p:PITA_TOP PITA 3.88E-28 2.10E-24 2.82E-27 2.59E-26 60 778 "CSMD3,SLITRK1,NLGN4X,LRRTM4,HPCAL4,SOX6,PKP4,PPM1E,NLGN1,LRRC4C,SLC1A2,SLC6A9,ARHGAP5,SON,SOX1,SOX5,JPH4,KIF1B,DNER,NCAM1,ERBIN,DCAF5,PCDH11X,ZNF638,SYT4,CAMTA1,GPM6A,CACNB2,ZEB1,TCF12,EML4,GRIA4,OPCML,TMEM257,ZFP91,PCDH8,PCSK2,CIART,HMGB1,PFKFB3,HNRNPK,NRXN1,SULT4A1,MEAF6,SF1,PPP3CB,PKN2,TOX,HP1BP3,OLFM3,PTPRD,KCNK2,PEX5,HS3ST4,SLC17A6,SUSD4,ABI1,FAM13C,PAK5,ZYG11B" MicroRNA hsa-miR-183-5p.2:TargetScan hsa-miR-183-5p.2 TargetScan 3.91E-28 2.12E-24 2.84E-27 2.60E-26 52 565 "ABAT,RIMKLA,KLHL32,LRRC7,FHL1,PKP4,PPM1E,MAGI3,GPAM,PDE8B,BRINP2,FYN,B3GALT2,GAD2,B4GALNT1,NPAS3,RAP1GAP2,NFASC,LMO3,GFRA1,AJAP1,CDK5R2,GPM6A,GPM6B,CACNA1E,GRIA1,GRID1,KCNK10,REPS2,HMGB1,PRRX1,POU3F2,MED1,CHD5,RIMS4,CTNND1,PMEPA1,CADM2,CDH20,PTPRD,RABGAP1L,KCNN3,DLG2,HS3ST4,CALN1,RALGDS,ATG16L1,GNE,BSDC1,JMJD1C,ABI2,PRRT4" MicroRNA hsa-miR-144-3p:TargetScan hsa-miR-144-3p TargetScan 4.16E-28 2.26E-24 3.02E-27 2.77E-26 59 751 "EPS8,LGR4,ARID1A,MDM4,GPR158,FOXG1,ANK2,ANK3,PPFIA1,APC,MAGI3,JAKMIP3,CCDC88A,ATP2B2,ARPP21,LMO3,RGL1,NEUROD1,AJAP1,FAM168A,NFIA,CAMSAP2,GPM6B,CACNB2,BRSK2,GRIK2,GRIK3,PTPN5,CDH8,PDE3B,DLGAP3,CADM1,KIAA1549L,PRRX1,FAT3,ACBD5,FMN2,PLD5,PUM1,PROX1,DPYSL5,PTCH1,DNAJC6,JAKMIP2,PTHLH,RGMA,CEP170,MAGI2,KCNA1,CDH20,KCND3,KCNN3,KIF2A,RASGRF1,DTNA,INSYN2,RBM12,ABI2,EPB41" MicroRNA hsa-miR-34a*:mirSVR_highEffct hsa-miR-34a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.21E-28 2.28E-24 3.04E-27 2.79E-26 70 1079 "SDE2,ACLY,RTN1,DSCAML1,TMEM156,LINC00461,LRRC7,FGF14,BCAR3,ERICH3,ANK2,ANK3,ITSN1,PKP4,GPAM,TACC2,NLGN1,MIER1,MSR1,ASPH,SORCS3,SMARCE1,RCOR3,B3GAT1,PALLD,USP33,CAB39,KIF1B,LMO3,CLASP2,ADHFE1,NEUROD1,SYT4,GNAS,CAMTA1,CAMSAP2,UNC5D,ADGRL3,ZEB1,EML4,VSTM2A,RFFL,GRIK2,LEFTY2,CDC42,TPM3,HMGB1,TMEFF2,CADM1,NMT2,SULT4A1,P2RY12,BTBD17,MFSD4A,PPP3CB,FEZ2,RBPJ,DOCK7,EDRF1,FGFR1OP2,JAKMIP2,STMN4,BLOC1S6,PLPPR4,KCNK2,RAB5B,SLC25A18,SLC6A15,ZNF248,SH3GLB1" MicroRNA hsa-miR-1308:mirSVR_lowEffct hsa-miR-1308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.65E-28 2.52E-24 3.36E-27 3.08E-26 74 1210 "SDE2,MAP6,WLS,RTKN,GRAMD1B,CHST15,SCN4B,LRRTM4,SCNN1D,LRRC7,BCAR3,HPCAL4,TRIM46,ANK2,PKP4,ST3GAL3,ZNF365,MIER1,SLC7A14,KIAA1614,MT3,NSG2,CADPS,TAGLN3,C10orf105,WDTC1,KIF21B,ALDH1L1,ADHFE1,PHLDB1,NEUROD1,VAMP1,KAZN,WWC1,ANO4,LRIT2,DDR2,GRIA2,ZDHHC22,TNFRSF1B,PADI2,PDE3B,BEST3,ANO5,CHRM1,HEPACAM,CCSER2,DNAJC12,SPATA6,CRLS1,PPP2R5C,RGS6,DOCK7,PRKCZ,LRRTM3,DNAJC6,JAKMIP2,KCNC1,KCNJ10,PCDH15,KCNMA1,NAV2,NKAIN1,PID1,TMEM255A,ATN1,BSDC1,VANGL2,SEC61A2,TMEM100,EPB41,EPB41L2,RCAN2,LRRC23" MicroRNA hsa-miR-664*:mirSVR_lowEffct hsa-miR-664*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.74E-28 2.57E-24 3.42E-27 3.14E-26 90 1772 "ACER3,SYT9,CLIP1,SORCS1,FOXRED2,SNX32,FGR,UNC79,MOG,TRIM46,ANK3,PPFIA1,DOCK10,SORBS1,BCAS1,MIER1,BCO1,SLC8A3,CCDC88A,SHANK2,DACH2,CADPS,SMARCE1,ATP1A2,DKK3,B4GALNT1,KIF1B,COLGALT2,BCL2L2,INKA2,RHBDL3,CASTOR3,DCLK2,GOLGB1,GPM6B,DDR1,CACNB2,PRLHR,PTBP2,NUDT21,PCDHGA3,CAMK2G,ATP13A2,OMG,CRB1,INA,TMEM9,TLL2,TMEM257,TNS1,PCDH9,DCLK1,PTGDR2,PDE1A,PDE2A,PRMT8,PLEKHB1,CCSER2,COL9A2,SLC36A4,FAT3,ATCAY,MFSD4A,PTPA,PPP2R5C,SNCAIP,NCAN,PRKAB2,FMN2,PKN2,USP54,KIAA0513,GON4L,LRRTM3,CA10,CADM2,PRDM2,HP1BP3,NTM,RABGAP1L,KCNJ10,PCDH15,SNX27,WIPF2,RALGDS,DTNA,BSDC1,ATL1,TTLL7,ELAVL4" MicroRNA hsa-miR-4259:mirSVR_lowEffct hsa-miR-4259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.80E-28 2.60E-24 3.46E-27 3.17E-26 82 1483 "RABEPK,TTYH1,MAP6,ASIC1,LGR4,MRVI1,SLC25A25,ADCY2,GRAMD1B,TUBB4A,TESK2,SLC30A10,MOBP,PI16,GPAM,ST3GAL3,MSR1,ARHGAP5,SLC8A2,SLC8A3,SPHKAP,ASPH,TMEM108,IGSF9B,SCN3B,SON,SOX10,GAD2,ZSWIM8,TTLL9,ADAM15,KIF1B,RAP1GAP2,COLGALT2,BCL2L2,ALDH1L1,DCAF5,FGF17,FAM168A,CASTOR3,POPDC3,KAZN,GNAS,WWC1,GPM6A,GPM6B,CAMK2G,CRB1,TGFBR3,INA,REPS2,TPM4,MAGI1,LINC01102,ASIC3,CCSER2,PLXNB3,BEST1,NECAB2,CRMP1,TENM4,NKAIN4,SDC3,PRKCG,NRSN1,FAM131B,ITGAV,MAGI2,OCIAD1,KCNC1,RABGAP1L,KCNJ10,ARNT2,WIPF2,FAM57B,C12orf4,GNE,SLC6A15,RFX4,RFX5,PHC2,SH3GLB1" MicroRNA hsa-miR-345:mirSVR_lowEffct hsa-miR-345:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.87E-28 2.64E-24 3.50E-27 3.21E-26 86 1626 "ABAT,ACER3,RCSD1,LDLRAD3,CSMD2,RXRG,WAC,FGF1,ASIC4,CNIH2,ZCCHC17,BCAN,ZNF365,KIAA1614,SLC1A7,MADD,ARFGAP2,SLCO1A2,TMEM108,SCN3B,USP33,LHFPL4,ADAM15,C11orf87,COLGALT2,GPR162,DCAF5,INKA2,FAM168A,CASTOR3,PCDH11X,NKX2-2,DDHD2,UNC5D,ACSL6,SYT6,GRIA2,GRID1,INA,AIFM1,TLL2,CELF3,PAH,TNFRSF1B,RBFOX2,MAGI1,PDE1A,PDE1C,LINC01102,ADGRG1,TMPRSS5,TUB,NOMO2,A2ML1,CCSER2,PMP2,BTF3L4,NSD2,FAT3,CHD1L,MED1,PNKD,RBPJ,PKN2,PLD5,NRSN1,SYTL2,PHYHIP,LRRTM3,PTCH1,RGMA,PTPRD,PTPRO,PTPRZ1,ARNT2,KCNK2,SLC17A6,FAM57B,SLC25A18,SLC6A15,ZYG11B,NUP214,JMJD1C,RGS7,CBLN2,SLC4A10" MicroRNA hsa-miR-411*:mirSVR_lowEffct hsa-miR-411*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.92E-28 2.66E-24 3.53E-27 3.24E-26 96 2000 "RABEPK,MBP,EYA1,FABP7,PLA2G6,LRRC7,BBOX1,UNC79,HPCAL4,SFPQ,APC,NTNG1,SORBS1,JAKMIP3,LRRC4C,AQP4,CCDC88A,SLIT1,MTR,SNAP25,MYT1L,TTLL9,KIF1B,DNER,NAP1L2,NDUFA5,ZNF302,DCAF5,GJB1,AJAP1,SYT4,KAZN,GPM6B,LRIT2,LILRA1,GPR19,TCF12,AZIN2,PTBP2,NUDT21,DDR2,PSD3,GRIA2,OPCML,P2RX7,MAEL,PC,PCDH8,CDH10,LGI1,PCSK2,PDE3B,ANO5,TUB,MS4A7,TMEFF2,JAM2,OPALIN,TJP2,BTF3L4,POU3F2,MED1,TENM4,OSBPL3,VCAN,PRKACB,DZIP3,NOS1AP,PROX1,KIAA0408,TOX,PTCH1,DNAJC6,PTHLH,STMN4,OLFM3,KCNA4,PLPPR4,NTM,PCDH15,KCNMA1,KCNN3,PEX5,DLG2,RAP1GAP,ABI1,GNE,RET,RGR,ATL1,RPRD1A,SLC4A10,EPB41L1,EPB41L2,UEVLD,BAALC" MicroRNA hsa-miR-3187:mirSVR_lowEffct hsa-miR-3187:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.04E-28 2.73E-24 3.61E-27 3.31E-26 76 1278 "RABEPK,MAPT,ATAT1,CLIP1,WAC,FHL1,HPCAL4,FOXG1,RASA3,PPM1E,NTNG1,ST3GAL3,DACH2,ASPH,WDTC1,SOX5,KIF21B,ZSWIM8,JPH4,NCAM1,COLGALT2,RND1,ABCC8,SYT4,UNC5D,MMD2,BTRC,CACNB2,CRB1,TMEM25,MAEL,TNR,C1orf94,PCDH9,MAGI1,PDE1C,ANO5,TLX1,ARHGAP22,GDAP1L1,KIAA1549L,NOMO2,TJP2,FLRT1,CHD1L,MED1,SNCAIP,MICAL2,ATRNL1,PRKAB2,DOCK7,DZIP3,NRSN1,ECE2,NOS1AP,TUBB2B,SYNC,PLPPR1,BDNF-AS,DKFZp779M0652,PTPRE,PTPRO,KCNK1,KCNMA1,DLG3,NKAIN1,HS3ST4,RALGDS,ATG16L1,GOPC,DBX2,ABCC9,INSYN2,VANGL2,SYT15,RBM12" MicroRNA hsa-miR-203a-3p.2:TargetScan hsa-miR-203a-3p.2 TargetScan 5.09E-28 2.76E-24 3.65E-27 3.35E-26 60 782 "RIMKLA,MRVI1,ADARB2,AMER2,ELMOD1,DOCK10,APC,DGKZ,JAKMIP3,CCDC88A,PDE8B,ATM,FYN,MEGF11,CAB39,GAD2,NMNAT2,NKX6-2,BCL2L2,AJAP1,FAM168A,GLS,KAZN,CAMTA1,GNG4,CACNA1E,NUDT21,PSD3,RFFL,ADAMTS8,INA,GUCY1A2,KCNK10,PADI2,PCDH8,PCDH9,CDH10,PCSK2,PDE3B,NEGR1,FAT3,MICAL2,MAPK8,MAPK10,PUM1,PROX1,PTCH1,KCNC1,KCNN3,KIF2A,C12orf4,RASGRF1,GNE,JMJD1C,RGS7,FAM135B,CACNG7,RAVER2,C2orf80,EN2" MicroRNA hsa-miR-668:mirSVR_lowEffct hsa-miR-668:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.12E-28 2.77E-24 3.66E-27 3.36E-26 77 1312 "ACER3,MAPT,MBP,MEG3,WLS,MDM4,ADD3,NLGN4X,CHST15,LRRC7,FOXG1,MOG,SOX6,GPAM,ST3GAL3,AQP4,NSG2,GPR153,DNAH17,ARFGAP1,NAXD,USP33,SOX10,ARPP21,NEK6,KIF1B,FXYD6,COLGALT2,NCDN,ZNF638,DCLK2,NKX2-2,CAMTA1,MMD2,ANO4,CACNA1A,GPM6A,CACNB2,DIRAS1,CAMK2G,P2RX7,TMEM257,C1orf94,CDH8,SEZ6L,TPD52,PCSK2,PDE3B,PRMT8,NRXN1,TJP2,FLRT1,NSD2,FAT3,MED1,CRLS1,PPP2R5C,RGS6,NCAN,RIMS4,PRKAB2,FMN2,USP54,COPS7A,OCIAD1,KCNJ10,PCDH15,KCNN3,ABI1,ZYG11B,RLBP1,SEC61A2,SLC39A12,GPR61,ABI2,RPE65,EPB41" MicroRNA hsa-miR-501-5p:mirSVR_highEffct hsa-miR-501-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.21E-28 2.82E-24 3.72E-27 3.41E-26 80 1415 "LGR4,FABP7,FCGR1A,SCN3A,PPFIA1,PKP4,APBA2,CACHD1,SHTN1,MIER1,RUFY2,CADPS,NAXD,CAPRIN2,ASPH,SORCS3,RCOR3,B3GALT2,ENKUR,COLGALT2,RGL1,ADHFE1,PCDH11X,ZNF638,KAZN,CAMTA1,CAMSAP2,CACNA1A,GPM6B,CACNB2,PTBP2,GRIA2,GRIA4,GRIK2,INA,TJP1,MAEL,DCLK1,LGI1,MAGI1,PDE4B,HPSE2,MS4A7,ZFYVE9,CCSER2,CNTN1,PMP2,PMS2,SPATA6,NXPH1,PPP3CB,KCNT2,DOCK7,PRKCZ,NRSN1,EDRF1,GON4L,LRRTM3,DNAJC6,PRDM2,MAGI2,NTM,KCNK1,DLG2,KIF2A,WIPF2,FAM66C,SLC25A41,FAM13C,NUP214,RET,RFX5,JMJD1C,SEC61A2,CACNG7,RBM12,GPR61,ELAVL4,TMEM100,BAALC" MicroRNA hsa-miR-299-5p:mirSVR_lowEffct hsa-miR-299-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.41E-28 2.93E-24 3.86E-27 3.54E-26 83 1521 "RABEPK,PRR5L,ACER3,TMEM74,ARID1A,WLS,SLITRK1,CDC7,CHST15,GPR158,LRRTM4,KIAA1109,FGF1,SEMA6A,FHL1,MOBP,AMPH,SGIP1,ANK3,USP28,PPFIA1,APC,GAS7,BCAN,CACHD1,NLGN1,SHTN1,PAAF1,ARHGAP5,CSPG5,BRINP2,RCOR3,ATM,DKK3,GAD2,ALDH1L1,NDUFA5,NEUROD1,GANAB,ACSBG1,ASTN2,ADGRL3,TBX15,GPM6B,LILRA1,TCF7L2,PTBP2,OMG,TMEM257,ZDHHC22,LGI1,TPM3,PCSK2,MAGI1,HMGB1,ANLN,CELF5,SPATA6,P2RY12,NSD2,ETNPPL,RNF14,SNCAIP,CSF3R,DOCK7,ANKS1B,PTHLH,CADM2,CEP170,KCNA1,SMG7,KCNJ10,PCDH15,ABI1,GOPC,FAM13C,RTN4,PAK5,RFX4,ATL1,TTLL7,RNF220,SLC39A12" MicroRNA hsa-miR-138-1*:mirSVR_lowEffct hsa-miR-138-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.28E-28 3.40E-24 4.47E-27 4.10E-26 86 1632 "EPS8,ACER3,ADGRV1,EYA1,MRVI1,CSMD3,ADCY2,WAC,SLC44A5,TOMM40L,GPR158,ACTL6B,MOBP,AMPH,ERICH3,USP28,PPM1E,DGKZ,MIER1,MSRA,ASPH,ASTN1,PALLD,B3GALT2,GAD2,NMNAT2,NEK6,NAP1L2,INKA2,ARHGEF7,POPDC3,UNC5D,ADGRL3,GPM6B,ATF7,ZEB1,VSTM2A,GRIA1,OMG,GUCY1A1,HPS5,TNR,C1orf94,PCDH9,SCRG1,JAM2,CADM1,CAMKV,NOMO2,ANLN,TJP2,NSD2,CNRIP1,MED1,CRLS1,FEZ2,RBPJ,PLD5,PUM1,KIAA0513,WBP1L,ANKS1B,PTCH1,CADM2,PRDM2,RGMA,KCNA4,OCIAD1,PTPRZ1,KCNK1,PCDH15,KCNMA1,KCNN3,PEX5,SLC17A6,PARP11,L1CAM,SLC6A15,RET,RGS7,INSYN2,VWA5A,ARHGAP12,TMEM100,EPB41L1,RCAN2" MicroRNA hsa-miR-921:mirSVR_lowEffct hsa-miR-921:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.56E-28 3.55E-24 4.67E-27 4.28E-26 80 1420 "ACER3,ATAT1,F3,FGF1,LRRC7,HPCAL4,MOBP,FOXG1,ITSN1,APBB1,GPAM,ZNF365,SFMBT2,ASPH,ATM,ATP1A2,NRG3,ATP2B2,B3GALT2,TNIK,ZCCHC24,ZSWIM8,KIF1B,NCAM1,DCAF5,AJAP1,ARHGEF7,RHBDL3,ZNF638,CAMTA1,GNG4,KLHL4,PRUNE2,ATF7,LRIT2,NRGN,PTBP2,EML4,VSTM2A,GRIA4,GRIK2,OPCML,ZDHHC22,KCNK10,MAEL,REPS2,DCLK1,LGI1,ZNF384,PDE3B,HMGB1,ANO5,ASIC3,SERPINE2,NRXN1,SEMA5B,PIK3CD,CNTN1,BTF3L4,SNCAIP,KCNT2,DZIP3,FMN2,NRSN1,HES5,KLK6,PLPPR5,CA10,KCNC1,C1orf109,RABGAP1L,KCNK1,KIF2A,FAM13C,BSDC1,JMJD1C,VANGL2,CBLN2,OLIG2,UEVLD" MicroRNA hsa-miR-136:mirSVR_highEffct hsa-miR-136:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.87E-28 3.72E-24 4.85E-27 4.45E-26 82 1491 "IL17D,MRVI1,CSMD3,ADD3,SORCS1,CHST15,LRRTM4,AMPH,SGIP1,PPFIA1,ITSN1,PKP4,GPAM,ZNF365,CCDC88A,SLC14A1,CADPS,CGREF1,RCOR3,SON,TNIK,JPH4,ARPP21,NEK6,C11orf87,NDUFA5,ZNF302,DCAF5,GLS,ZNF638,GNAS,CAMTA1,CAMSAP2,ADGRL3,ANO4,CACNA1E,TCF7L2,ZEB1,CAMK2G,GRIA1,GRID1,OLR1,TMEM25,INA,TPD52,TPM3,PDE3B,PRMT8,TMEFF2,CADM1,SEMA5B,CNTN1,SPATA6,ACBD5,SNCAIP,RGS6,OSBPL3,VCAN,ARHGEF4,IGSF1,NOS1AP,MASP1,SPIRE1,SYNC,DNAJC6,PRDM2,PRTFDC1,PTPRE,NTM,KCNJ4,RABGAP1L,CCDC3,PCDH15,HS3ST4,FAM66C,DTNA,PAK5,JMJD1C,ZNF248,EFNA3,EPB41,UEVLD" MicroRNA hsa-miR-548b-5p:PITA hsa-miR-548b-5p:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548c-5p:PITA hsa-miR-548c-5p:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548d-5p:PITA hsa-miR-548d-5p:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548j:PITA hsa-miR-548j:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548a-5p:PITA hsa-miR-548a-5p:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548i:PITA hsa-miR-548i:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-548h:PITA hsa-miR-548h:PITA_TOP PITA 6.89E-28 3.73E-24 4.85E-27 4.45E-26 62 844 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA hsa-miR-429:TargetScan hsa-miR-429 TargetScan 7.19E-28 3.90E-24 5.05E-27 4.63E-26 63 874 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,ADD3,NLGN4X,GPR158,FOXG1,ANK3,PPFIA1,ITSN1,CACHD1,JAKMIP3,FYN,SCN3B,CAB39,GAD2,NFASC,NCAM1,C11orf87,CLASP2,DCAF5,RGL1,PHLDB1,NFIA,CAMSAP2,MMD2,GPM6A,CECR2,FBXL16,PCDH8,RBFOX2,ARHGAP19,PCSK2,ANO5,HNRNPK,CADM1,NEGR1,ANLN,BTF3L4,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,PROX1,RIMS3,LRRTM3,PTCH1,JAKMIP2,PTHLH,CDH20,KCND3,DTNA,ABCC9,SEC61A2,RPRD1A,ABI2,ELAVL4" MicroRNA hsa-miR-200b-3p:TargetScan hsa-miR-200b-3p TargetScan 7.19E-28 3.90E-24 5.05E-27 4.63E-26 63 874 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,ADD3,NLGN4X,GPR158,FOXG1,ANK3,PPFIA1,ITSN1,CACHD1,JAKMIP3,FYN,SCN3B,CAB39,GAD2,NFASC,NCAM1,C11orf87,CLASP2,DCAF5,RGL1,PHLDB1,NFIA,CAMSAP2,MMD2,GPM6A,CECR2,FBXL16,PCDH8,RBFOX2,ARHGAP19,PCSK2,ANO5,HNRNPK,CADM1,NEGR1,ANLN,BTF3L4,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,PROX1,RIMS3,LRRTM3,PTCH1,JAKMIP2,PTHLH,CDH20,KCND3,DTNA,ABCC9,SEC61A2,RPRD1A,ABI2,ELAVL4" MicroRNA hsa-miR-200c-3p:TargetScan hsa-miR-200c-3p TargetScan 7.19E-28 3.90E-24 5.05E-27 4.63E-26 63 874 "EPS8,ABAT,CSMD3,CLIP1,ADCY2,ADD3,NLGN4X,GPR158,FOXG1,ANK3,PPFIA1,ITSN1,CACHD1,JAKMIP3,FYN,SCN3B,CAB39,GAD2,NFASC,NCAM1,C11orf87,CLASP2,DCAF5,RGL1,PHLDB1,NFIA,CAMSAP2,MMD2,GPM6A,CECR2,FBXL16,PCDH8,RBFOX2,ARHGAP19,PCSK2,ANO5,HNRNPK,CADM1,NEGR1,ANLN,BTF3L4,FAT3,NXPH1,MED1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,PROX1,RIMS3,LRRTM3,PTCH1,JAKMIP2,PTHLH,CDH20,KCND3,DTNA,ABCC9,SEC61A2,RPRD1A,ABI2,ELAVL4" MicroRNA hsa-miR-449a:TargetScan hsa-miR-449a TargetScan 8.34E-28 4.52E-24 5.82E-27 5.34E-26 51 549 "MAPT,LGR4,MDM4,AMER2,GPR158,LRRC7,ELMOD1,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,DGKZ,LRRC55,CCDC88A,B3GAT1,ATP1A2,PALLD,CPLX2,GFRA1,CNTN2,CACNA1E,GPR26,PSD3,GRID1,INA,CELF3,LGI1,PDE4B,HMGB1,GDAP1L1,NRXN2,NMT2,FAT3,PRKACB,IGSF1,CTNND1,CTNND2,FAM131B,NOS1AP,PROX1,RIMS3,PTPRD,KCND3,KCNN3,CALN1,RALGDS,RAP1GAP,RET,JMJD1C" MicroRNA hsa-miR-34c-5p:TargetScan hsa-miR-34c-5p TargetScan 8.34E-28 4.52E-24 5.82E-27 5.34E-26 51 549 "MAPT,LGR4,MDM4,AMER2,GPR158,LRRC7,ELMOD1,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,DGKZ,LRRC55,CCDC88A,B3GAT1,ATP1A2,PALLD,CPLX2,GFRA1,CNTN2,CACNA1E,GPR26,PSD3,GRID1,INA,CELF3,LGI1,PDE4B,HMGB1,GDAP1L1,NRXN2,NMT2,FAT3,PRKACB,IGSF1,CTNND1,CTNND2,FAM131B,NOS1AP,PROX1,RIMS3,PTPRD,KCND3,KCNN3,CALN1,RALGDS,RAP1GAP,RET,JMJD1C" MicroRNA hsa-miR-34a-5p:TargetScan hsa-miR-34a-5p TargetScan 8.34E-28 4.52E-24 5.82E-27 5.34E-26 51 549 "MAPT,LGR4,MDM4,AMER2,GPR158,LRRC7,ELMOD1,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,DGKZ,LRRC55,CCDC88A,B3GAT1,ATP1A2,PALLD,CPLX2,GFRA1,CNTN2,CACNA1E,GPR26,PSD3,GRID1,INA,CELF3,LGI1,PDE4B,HMGB1,GDAP1L1,NRXN2,NMT2,FAT3,PRKACB,IGSF1,CTNND1,CTNND2,FAM131B,NOS1AP,PROX1,RIMS3,PTPRD,KCND3,KCNN3,CALN1,RALGDS,RAP1GAP,RET,JMJD1C" MicroRNA hsa-miR-449b-5p:TargetScan hsa-miR-449b-5p TargetScan 8.34E-28 4.52E-24 5.82E-27 5.34E-26 51 549 "MAPT,LGR4,MDM4,AMER2,GPR158,LRRC7,ELMOD1,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,DGKZ,LRRC55,CCDC88A,B3GAT1,ATP1A2,PALLD,CPLX2,GFRA1,CNTN2,CACNA1E,GPR26,PSD3,GRID1,INA,CELF3,LGI1,PDE4B,HMGB1,GDAP1L1,NRXN2,NMT2,FAT3,PRKACB,IGSF1,CTNND1,CTNND2,FAM131B,NOS1AP,PROX1,RIMS3,PTPRD,KCND3,KCNN3,CALN1,RALGDS,RAP1GAP,RET,JMJD1C" MicroRNA hsa-miR-32:mirSVR_highEffct hsa-miR-32:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.39E-28 4.54E-24 5.84E-27 5.36E-26 72 1156 "RBM10,TMEM74,LGR4,CSMD2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,ERICH3,ANK3,USP28,SESN3,SLITRK3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,SON,B3GALT2,ARPP21,KIF1B,NPAS3,CLASP2,RGL1,AJAP1,ARHGEF7,PCDH11X,ZNF638,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,LILRA1,ZEB1,TCF12,CAMK2A,GRIA1,RFFL,P2RX7,AIFM1,CDH10,TPM4,PDE1A,ZMYND8,SCRG1,CCSER2,CNRIP1,MED1,KCNT2,ATRNL1,FMN2,RAB39A,USP54,EDRF1,ITGAV,CA10,LRP8,PTPRD,PLPPR4,PTPRO,PEX5,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65" MicroRNA hsa-miR-3134:mirSVR_lowEffct hsa-miR-3134:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.71E-28 4.72E-24 6.06E-27 5.56E-26 77 1323 "TTYH1,SYT9,MRVI1,ATAT1,WAC,GRAMD1B,FOXRED2,KIAA1109,MOBP,ERICH3,APC,NTNG1,BCAS1,MIER1,SLC7A14,RPH3A,ASPH,TMEM108,ATP2B2,B3GALT2,AHCYL1,EMC1,BCL2L2,ALDH1L1,HEPN1,RGL1,CASTOR3,NHLH1,KAZN,UNC5D,ADGRL3,VWC2,LRIT2,ZEB1,GRIA1,LINC00839,NEURL1,ZDHHC22,CDC42,IGSF21,PADI2,TNS1,CDH8,CDH10,LGI1,PIRT,HPSE2,CCSER2,OPALIN,DNAJC12,PMP2,COL9A2,SPATA6,MED1,PPP3CB,RGS6,ATRNL1,CTNND2,SPIRE1,ZNF385B,COPS7A,PTPRD,KCNA6,PTPRO,SRGAP3,SNX27,DLG3,KIF2A,DNAH9,TMEM255A,SLC17A6,PARP11,ATN1,FAM13C,DBX2,RFX4,RGR" MicroRNA hsa-miR-559:PITA hsa-miR-559:PITA_TOP PITA 8.90E-28 4.82E-24 6.19E-27 5.67E-26 62 848 "EYA1,CLIP1,RTN1,GPR158,SCN3A,FOXG1,SOX6,ERICH3,DOCK10,CCDC88A,ASCL1,CAPRIN2,BRINP2,MEGF11,SON,SOX5,CAB39,LMO3,CLASP2,BCL2L2,DCAF5,RGL1,NEUROD1,PCDH11X,CAMTA1,CAMSAP2,TCF12,NUDT21,CECR2,GRIA4,INA,CELF3,TMEM257,CD81,PCDH9,PDE4B,SERPINE2,CADM1,NRXN1,NEGR1,MEAF6,BTF3L4,MED1,PPP3CB,CHD5,PRKACB,DZIP3,RAB39A,CTNND2,EDRF1,TOMM20,LRRTM3,PTCH1,ITGAV,PTPRD,PTPRE,PCDH15,DLG3,KIF2A,TMEM255A,EPB41L2,RCAN2" MicroRNA "CTTTGTA,MIR-524:MSigDB" "CTTTGTA,MIR-524:MSigDB" MSigDB 9.11E-28 4.93E-24 6.33E-27 5.80E-26 45 409 "CNTNAP3,LGR4,CSMD3,UNC79,SLITRK3,API5,MIER1,ATP2B2,USP33,SON,CPLX2,LMO3,ERBIN,NFIA,ASTN2,MYRF,GPM6A,TCF7L2,GRIA2,GRID1,TJP1,ZFP91,PAX6,CDC42,PCDH9,DCLK1,TPM3,PDE2A,HNRNPK,NLGN3,PRRX1,CNRIP1,CRMP1,PUM1,PSD,LRRTM3,CSDE1,PTPRE,PEX5,SLC17A6,BSDC1,JMJD1C,RNF220,EPB41,RCAN2" MicroRNA hsa-miR-3175:mirSVR_highEffct hsa-miR-3175:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.31E-28 5.04E-24 6.46E-27 5.92E-26 65 938 "SERPINA3,CLIP1,ADCY2,ADORA3,SNX32,FGF1,SEMA6A,ASIC4,MOBP,SOX6,PPM1E,NTNG1,PKNOX2,MT3,NSG2,SORCS3,SNCB,MEGF11,SON,ZSWIM8,B4GALNT1,C11orf87,GANAB,FAM168A,C1QC,SYT4,UNC5D,MMD2,WSCD1,PRLHR,SYT6,INA,ZNF384,GDAP1L1,NRXN1,UBTF,CNTN1,MEAF6,COL9A2,NSD2,POU3F2,PNKD,SF1,VCAN,PRKACB,DZIP3,FMN2,CTNND1,NRSN1,KLK6,SYNC,PTHLH,MAGI2,SMG7,SV2A,KCNK2,KCNN3,PLEKHB2,DTNA,BSDC1,PHC2,SEC61A2,PIANP,RPRD1A,BSCL2" MicroRNA hsa-miR-934:mirSVR_lowEffct hsa-miR-934:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.73E-28 5.27E-24 6.73E-27 6.18E-26 67 1000 "MAP6,PAQR6,EYA1,FAM43B,CSMD3,RTN1,FABP7,SLC44A5,TOMM40L,FGF14,ERICH3,PKP4,NLGN1,SHTN1,MSR1,SLC8A3,ASTN1,PALLD,GAD2,ENKUR,EMC1,DNER,NCAM1,DCAF5,NEUROD1,POPDC3,CAMTA1,CAMSAP2,ADGRL3,VWC2,ZEB1,PTBP2,TJP1,KCNK10,PADI2,PCDH9,DCLK1,ANO5,CASC2,TMEFF2,NEGR1,BTF3L4,NSD2,FAT3,MFSD4A,MED1,PPP2R5C,ATRNL1,RBPJ,PRKCZ,PUM1,BRINP3,ZBTB16,LRRTM3,PMEPA1,BDNF-AS,CADM2,PRDM2,BLOC1S6,KCNA1,PTPRE,PTPRZ1,KCNJ9,NAV2,ZYG11B,RBM12,OLIG2" MicroRNA hsa-let-7f:mirSVR_lowEffct hsa-let-7f:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.74E-28 5.27E-24 6.73E-27 6.18E-26 90 1790 "RABEPK,ACER3,CDHR1,MEG3,RTKN,CSMD3,GALNT13,SORCS1,ADORA3,TUBB4A,TOMM40L,SCN4B,ASIC4,ANK1,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,RUFY2,MSR1,SLC8A2,SLCO1A2,C10orf105,USP33,B3GALT2,ZSWIM8,ADAM15,NPAS3,NDUFA5,STOX1,MLC1,BTRC,GOLGB1,ATF7,GPR26,PTBP2,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,MAEL,PAX6,TNFRSF1B,PCDH9,TPM3,LINC01102,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,CELF5,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,PRKACB,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,LRP8,CSDE1,BLOC1S6,PTPRD,KCNC1,RABGAP1L,KCNJ10,TMCC2,NKAIN1,DSCAM,RASGRF1,BSDC1,SLC6A15,NUP214,RBM12,ELAVL4,EPB41L2" MicroRNA hsa-miR-151-3p:mirSVR_lowEffct hsa-miR-151-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.95E-28 5.39E-24 6.88E-27 6.31E-26 74 1225 "PRR5L,MRVI1,ATAT1,CSMD3,DSCAML1,ERMN,HOGA1,LRRC7,ASIC4,HPCAL4,SOX6,ANXA7,CCDC80,MSRA,YPEL4,CGREF1,CSPG5,SORCS3,SMARCE1,MEGF11,SON,TNIK,CAB39,GART,DNER,SPART,NCAM1,NDUFA5,GFAP,RGL1,SEPT3,SLCO1C1,VAMP1,SYT4,PRUNE2,LILRA1,NRGN,PTBP2,NUMA1,OMG,OPCML,LEFTY2,INA,PAX6,IGSF21,PDE1C,SCRG1,FADS2,SPATA6,NXPH1,MFSD4A,POU3F2,NCAN,CTNND1,MASP1,TOX,SYNC,ELMO1,PRDM2,ZC3H11A,KCNA2,KCNC1,SRGAP3,NTM,DNM2,ABI1,PAK5,ABCC9,RET,RFX5,INSYN2,EFNA3,SH3GLB1,SEZ6" MicroRNA hsa-miR-4314:mirSVR_lowEffct hsa-miR-4314:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-27 6.10E-24 7.77E-27 7.13E-26 92 1869 "ZFYVE27,MBP,SYT9,CEND1,ADGRV1,ADARB2,ADORA1,FOXRED2,SNX32,HOGA1,TESK2,HPCAL4,MOBP,CDC42BPA,PI16,CNIH2,PPFIA1,MAGI3,SHTN1,AQP4,KIAA1614,MADD,ARHGAP5,SCMH1,SORCS3,B3GAT1,NRG3,MYBPC1,SOX5,NMNAT2,NPAS3,NCAM1,COLGALT2,GFAP,SEPT3,AJAP1,FAM168A,KLHL4,ANO4,TBX15,PRUNE2,VWC2,TCF12,NRGN,AZIN2,VXN,GRIA4,GRM3,OLR1,OPCML,LINC00839,SEZ6L,LGI1,TPM3,ZNF384,PDE3B,HPSE2,ANO5,HPCA,DLGAP3,CNTN1,MEAF6,CRLS1,SNCAIP,RGS6,OSBPL3,PRKAB2,SDC3,CTNND2,EDRF1,NOS1AP,MASP1,WBP1L,SIRPA,PTCH1,PRDM2,BLOC1S6,C1orf109,NAV2,DLG2,DLG3,CAB39L,WIPF2,RASGRF1,L1CAM,BSDC1,ZYG11B,NUP214,RET,ZNF248,SIDT2,VWA5A" MicroRNA hsa-miR-432:mirSVR_highEffct hsa-miR-432:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.15E-27 6.22E-24 7.91E-27 7.26E-26 62 852 "SYT9,FAM43B,ATAT1,MDM4,RXRG,GALNT13,FABP7,FCGR1A,LRRTM4,SGIP1,PPFIA1,GPAM,ST3GAL3,SHTN1,CCDC88A,ASPH,EIF4G3,MEGF11,GABBR1,NASP,INKA2,ADHFE1,NEUROD1,GLS,ADGRL3,PTBP2,NUDT21,EML4,VSTM2A,GRIA2,GRIA4,CRB1,USP2,TJP1,TLL2,TMEM257,MAEL,LGI1,TPM3,PCSK2,KIAA1549L,CHD1L,RNF14,FEZ2,PRKCG,PKN2,PLD5,ARHGEF4,CTNND1,MASP1,TOX,ANKS1B,DNAJC6,BDNF-AS,CEP170,C12orf4,RASGRF1,DBX2,DTNA,RGS7,ARHGEF10L,CACNG7" MicroRNA hsa-miR-3146:mirSVR_lowEffct hsa-miR-3146:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.28E-27 6.90E-24 8.77E-27 8.05E-26 76 1297 "PRR5L,MRVI1,MDM4,RTN1,ERMN,CHST15,LINC00461,KIAA1109,LRRC7,FGR,SELL,ANK2,ANK3,SESN3,NLGN1,BCAS1,CCDC88A,SLCO1A2,SLIT1,ASPH,SMARCE1,RCOR3,SNAP25,ATM,MEGF11,DKK3,GABBR1,ENKUR,DNER,NPAS3,SPART,NCAM1,NDUFA5,GLS,PCDH11X,LUZP2,TMEM136,ACSL6,CACNA1E,TCF7L2,TJP1,ZDHHC22,PCDH9,ARHGAP19,CASC2,HEPACAM,DUSP26,NRXN1,BTF3L4,SPATA6,CP,CHD1L,PPP3CB,OSBPL3,PRKACB,DOCK7,DZIP3,FMN2,PLPP4,USP54,NRSN1,TOX,GON4L,TOMM20,PTCH1,ELMO1,TMCC2,PCDH15,KCNMA1,DLG2,KIF2A,RAB5B,PID1,SLC17A6,RGS10,BAALC" MicroRNA hsa-miR-26a:mirSVR_lowEffct hsa-miR-26a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-27 7.11E-24 9.02E-27 8.27E-26 93 1911 "PRR5L,ACER3,EYA1,ARID1A,KLHL32,SORCS1,NLGN4X,SLC44A5,FCGR1B,LRRC7,MOBP,SELL,AMPH,ASRGL1,ANK2,PPFIA1,ITSN1,PKP4,NTNG1,MAGI3,GPAM,SLITRK3,ST3GAL3,API5,MSRA,LRRC55,ARHGAP5,SHANK2,SLIT1,SMARCE1,ATM,PHYHIPL,KIF21B,BCL2L2,ADHFE1,NEUROD1,SEPT3,PCDH11X,DDHD2,CAMTA1,ANO4,GPM6B,TCF12,NUDT21,CECR2,PSD3,GRIK2,OPCML,TMEM25,GUCY1A1,KCNK10,C1orf94,SEZ6L,TPD52,PDE4B,PDYN,SCRG1,CASC2,CHRNB2,HNRNPK,TMEFF2,GDAP1L1,PIK3CD,A2ML1,VAV2,NSD2,CP,ATRNL1,PRKACB,DOCK7,PUM1,EDRF1,KIAA0408,TOX,ZNF385B,PTCH1,ITGAV,BDNF-AS,ELMO1,OCIAD1,PTPRE,KCNH1,RABGAP1L,CAB39L,PID1,SLC17A6,ATG16L1,RET,SEC61A2,SSPN,RBM12,RPE65,SEZ6" MicroRNA hsa-miR-660:mirSVR_highEffct hsa-miR-660:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-27 7.26E-24 9.20E-27 8.44E-26 59 768 "ABAT,MEG3,LDLRAD3,SCN3A,LRRTM4,KIAA1109,LRRC7,UNC79,SFPQ,FOLH1,USP28,ITSN1,PKP4,NTNG1,MAGI3,GPAM,SLITRK3,MIER1,ARFGAP2,SCG3,ASPH,SON,JPH4,NPAS3,SPART,ALDH1L1,SMOC1,GLS,GNAS,CAMSAP2,CECR2,AIFM1,CELF3,PCDH9,PCSK2,MAGI1,MS4A7,DUSP26,ZFYVE9,KIAA1549L,A2ML1,FAAP20,PPP3CB,DOCK7,TOX,KIAA0513,ZNF385B,HP1BP3,LRP8,NTM,DPP6,DTNA,PAK5,ABCC9,SLC6A15,INSYN2,RBM12,CBLN2,YY1AP1" MicroRNA hsa-miR-183:mirSVR_highEffct hsa-miR-183:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.39E-27 7.52E-24 9.51E-27 8.73E-26 62 855 "ABAT,RCSD1,MDM4,CSMD3,CLIP1,SLITRK1,WAC,LRRC7,PKP4,NTNG1,MAGI3,GPAM,SLITRK3,MIER1,SLCO1A2,ASPH,SORCS3,ASTN1,SMARCE1,RCOR3,ATM,PALLD,ARPP21,GART,NPAS3,NFASC,NCAM1,LMO3,ERBIN,ADHFE1,AJAP1,SLCO1C1,ABCC8,PCDH11X,GPM6A,TCF7L2,ZEB1,TCF12,EML4,GRIK2,P2RX7,KCNK10,TPM3,PDE3B,CNRIP1,CP,PPP2R5C,PRKACB,SIRPA,PTPRE,PTPRZ1,KCNK2,PEX5,KIF2A,FAM13C,DTNA,PAK5,FAM135B,ZNF248,TTLL7,SEC61A2,RAVER2" MicroRNA hsa-miR-548e:PITA hsa-miR-548e:PITA_TOP PITA 1.50E-27 8.12E-24 1.03E-26 9.42E-26 61 827 "CSMD3,RTN1,ADCY2,NLGN4X,LRRC7,AMPH,CDC42BPA,NLGN1,CCDC88A,DACH2,B3GAT1,WDTC1,SOX1,MYT1L,ZCCHC24,LMO3,CLASP2,ERBIN,RGL1,NFIA,ARHGEF7,GLS,SYT4,DCLK2,CAMTA1,CAMSAP2,WWC1,ZEB1,PTBP2,PTPN5,TGFBR3,CDH10,TUB,NRXN2,NEGR1,CCSER2,NSD2,ACBD5,POU3F2,CRMP1,ATRNL1,CTNND2,BRINP3,TOMM20,LRRTM3,PTCH1,CA10,PMEPA1,CSDE1,ZC3H11A,SNX27,KIF2A,RAB5B,PID1,GOPC,DSCAM,PAK5,ZYG11B,RBM12,ABI2,EPB41L1" MicroRNA hsa-miR-335:mirSVR_highEffct hsa-miR-335:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.52E-27 8.22E-24 1.04E-26 9.52E-26 63 886 "PRR5L,MAP6,TMEM74,RCSD1,CDC7,SORCS1,C1orf61,SELL,SYBU,PAAF1,ASPH,ATM,DKK3,SON,ZSWIM8,NAP1L2,GFAP,RND1,AJAP1,SLCO1C1,DDHD2,TMEM136,KLHL4,PRUNE2,GUCY1A1,TMEM257,CDC42,PCDH9,RBFOX2,LGI1,NRXN1,A2ML1,TJP2,BTF3L4,NXPH1,CNRIP1,MFSD4A,MED1,CRLS1,PPP2R5C,MICAL2,OSBPL3,DZIP3,FMN2,ARHGEF4,MAPK10,FAM131B,ZBTB16,SYNC,PRDM2,HP1BP3,OCIAD1,KCNC1,FAM66C,GOPC,ATL1,ZNF248,SLC39A12,ARHGAP12,SLC4A10,ELAVL3,C2orf80,EPB41" MicroRNA hsa-miR-219-5p:mirSVR_lowEffct hsa-miR-219-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-27 8.53E-24 1.08E-26 9.87E-26 73 1201 "CSMD3,GALNT13,SORCS1,GRAMD1B,LRRC7,FHL1,SOX6,ITSN1,ANXA7,LRRC4C,SHTN1,SLC8A2,CCDC88A,CAPRIN2,SMARCE1,ATP1A2,NRG3,PHYHIPL,B3GALT2,AHCYL1,ENKUR,NEK6,KIF1B,RAP1GAP2,NFASC,C11orf87,DCAF5,RGL1,VAMP1,PCDH11X,NHLH1,OS9,NODAL,WWC1,LILRA1,ZEB1,PTBP2,CAMK2G,GRIA4,TF,SHISA7,CRB1,TJP1,REPS2,PDE2A,PFKFB3,CASC2,A2ML1,FADS2,NSD2,SF1,CRLS1,PPP2R5C,SNCAIP,DZIP3,CTNND2,HES5,BRINP3,ANKS1B,ZNF385B,SYNC,LRRTM3,CSDE1,MAGI2,KCNK2,KCNMA1,PID1,SLC17A6,PAK5,SLC6A15,ATL1,SEC61A2,GPR61" MicroRNA hsa-miR-3130-5p:mirSVR_lowEffct hsa-miR-3130-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-27 8.89E-24 1.12E-26 1.03E-25 74 1235 "SDE2,CDHR1,LGR4,RTN3,ARID1A,WLS,F3,TOMM40L,GPR158,TESK2,KIAA1109,ASIC4,ELMOD1,MOG,SOX6,ANK3,ITSN1,APC,GPAM,ST3GAL3,JAKMIP3,LRRC4C,LRRC55,PKNOX2,DACH2,SCMH1,NAXD,SON,SOX1,KIF1B,ALDH1L1,ZNF302,RGL1,GJB1,POPDC3,ROBO3,CNTN2,ANO4,TBX15,PRUNE2,AKNA,LINC00839,LEFTY2,TIE1,REPS2,HPS5,TPM3,JAM2,NLGN3,CAMKV,TJP2,VAV2,IFFO1,CNRIP1,MFSD4A,PRKAB2,FMN2,WBP1L,SPIRE1,SYNC,BDNF-AS,OCIAD1,SMG7,PTPRE,RABGAP1L,CCDC3,KCNK2,PLEKHB2,SLC25A18,RASGRF1,RLBP1,GPR61,EPB41,RCAN2" MicroRNA hsa-miR-511:PITA hsa-miR-511:PITA_TOP PITA 1.68E-27 9.11E-24 1.15E-26 1.05E-25 49 508 "DPF1,RIMKLA,EYA1,MRVI1,CSMD2,ARID1A,ERMN,NLGN4X,SEMA6A,CCDC80,TACC2,LRRC4C,SORCS3,EIF4G3,ATP2B2,ZCCHC24,GAD2,CLASP2,ERBIN,GFAP,GFRA1,RGL1,PHLDB1,CAMTA1,EML4,TGFBR3,FNDC5,NRXN1,NEGR1,CCSER2,NXPH1,PPP2R5C,TENM4,ATRNL1,PHACTR3,PKN2,DNAJC6,PMEPA1,CADM2,KCNA1,SMG7,SRGAP3,DLG2,DLG3,PARP11,FAM135B,VANGL2,ABI2,ELAVL3" MicroRNA hsa-miR-27b*:mirSVR_lowEffct hsa-miR-27b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-27 9.22E-24 1.16E-26 1.06E-25 76 1303 "MRVI1,ATAT1,SORCS1,GRAMD1B,MOBP,FOXM1,ITSN1,SLITRK3,SHTN1,LRRC55,SLC8A3,SLC14A1,SPHKAP,ASPH,RCOR3,MEGF11,DKK3,SCN3B,ZSWIM8,CPLX2,NPAS3,BCL2L2,STOX1,DCAF5,ARHGEF7,GLS,GNAS,DDHD2,BTRC,WSCD1,GPM6A,FAM69C,CACNB2,NUDT21,CRB1,TMEM9,TMEM257,REPS2,HPS5,PDE3B,PLEKHB1,CASC2,TUB,ZFYVE9,DNAJC12,PRRX1,MFSD4A,TENM4,KCNT2,MICAL2,RBPJ,PRKAB2,DZIP3,SDC3,PLD5,ANKS1B,GON4L,TUBB2B,PRTFDC1,MAGI2,OLFM3,OCIAD1,AK5,CCDC3,KCNK2,PEX5,WIPF2,RALGDS,ATN1,BSDC1,ABCC9,RFX4,RNF220,RAVER2,SLC4A10,EN2" MicroRNA hsa-miR-448:TargetScan hsa-miR-448 TargetScan 1.84E-27 9.96E-24 1.25E-26 1.15E-25 49 509 "ABAT,RIMKLA,SCN4B,ANK1,ANK3,APC,NLGN1,JAKMIP3,PKNOX2,NRG3,ATP2B2,NMNAT2,NPAS3,NFASC,C11orf87,DCAF5,FAM168A,NFIA,ACSL6,PCDHGA3,PSD3,RFFL,GRIK2,GRIK3,GRIK4,ADAMTS8,INA,GUCY1A2,KCNK10,PCDH8,CDH10,DCLK1,HNRNPK,NMT2,CCSER2,FAT3,PRKAB2,PROX1,CADM2,KCNA4,KCNA6,PTPRE,KIF2A,RAB5B,CALN1,DTNA,PIANP,EFNA3,RAVER2" MicroRNA hsa-miR-633:mirSVR_highEffct hsa-miR-633:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.92E-27 1.04E-23 1.30E-26 1.20E-25 83 1550 "SDE2,KLHL32,GALNT13,WAC,SORCS1,ERMN,FCGR1A,GPR158,LRRTM4,KIAA1109,SLC30A10,GPAM,NLGN1,SHTN1,RUFY2,MSR1,CCDC88A,SLC14A1,DACH2,DLL3,NAXD,ASPH,SORCS3,SON,MYT1L,B3GALT2,CAB39,ILDR2,DNER,LMO3,STOX1,NEUROD1,AJAP1,SLCO1C1,CAMTA1,GPM6B,ACSL6,VWC2,NUDT21,CAMK2G,VXN,GRIA2,GRIA4,INA,CIART,BEST3,HMGB1,TMEFF2,JAM2,ZFYVE9,PMP2,P2RY12,CP,POU3F2,FEZ2,RBPJ,DOCK7,RAB39A,USP54,NRSN1,EDRF1,TOX,CADM2,PRDM2,CEP170,BLOC1S6,OLFM3,KCNA4,C1orf109,PCDH15,SLC17A6,PLEKHB2,RAD52,FAM66C,C12orf4,DBX2,DTNA,ABCC9,ATL1,CBLN2,RPE65,EPB41,EPB41L2" MicroRNA hsa-miR-25:mirSVR_highEffct hsa-miR-25:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-27 1.10E-23 1.38E-26 1.27E-25 67 1013 "RBM10,TMEM74,SYT9,CSMD2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FHL1,MOBP,MOG,ANK3,USP28,SESN3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,B3GALT2,B4GALNT1,KIF1B,NPAS3,RGL1,PCDH11X,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,CAMK2A,GRIA1,RFFL,P2RX7,AIFM1,CDH10,TPM4,PDE1A,SCRG1,CCSER2,CNRIP1,PPP3CB,KCNT2,ATRNL1,FMN2,USP54,EDRF1,ITGAV,PMEPA1,BDNF-AS,PRDM2,LRP8,PTPRD,PLPPR4,PTPRO,KCNK1,PEX5,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65" MicroRNA hsa-miR-760:mirSVR_highEffct hsa-miR-760:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-27 1.13E-23 1.41E-26 1.29E-25 56 691 "LOC100128239,ARID1A,MOBP,ERICH3,PPFIA1,ITSN1,APBB1,BCAN,SORBS1,SHTN1,ZNF365,MIER1,MSR1,CAPRIN2,RCOR3,GABBR1,CADM3,NMNAT2,FXYD6,RND1,ABCC8,GNG3,NUDT21,NUMA1,GRIA4,GRIN1,GPR88,CYB561A3,MFSD2A,TMEM257,CDC42,CDH8,LINC01102,CAMKV,PIK3CD,TJP2,PNKD,VCAN,NCAN,PUM1,KIAA0513,PRDM2,AK5,KCNJ10,DLG3,CAB39L,KIF2A,DNAH9,SLC25A48,FAM13C,SLC6A15,FAM135B,ARHGEF10L,GPR61,ABI2,SLC4A10" MicroRNA hsa-miR-510:mirSVR_lowEffct hsa-miR-510:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.25E-27 1.22E-23 1.52E-26 1.39E-25 91 1849 "SDE2,ABAT,ACER3,MAP6,TMEM74,CEND1,ACTN2,MRVI1,MDM4,KCNIP2,CSMD3,KLHL32,PNMA8B,SNX30,HOGA1,SEMA6A,FHL1,ASRGL1,ANK2,DGKD,SORBS1,ST8SIA1,PAAF1,ZNF365,MADD,MSR1,CCDC88A,NSG2,ASCL1,LGI3,NAXD,CAPRIN2,EIF4G3,FYN,SCN3B,MYBPC1,B3GALT2,NMNAT2,NFASC,GPR162,GFAP,PCDH11X,DCLK2,SEMA4A,NODAL,MYRF,TMEM136,FAM69C,GPR17,PTBP2,AKNA,USP2,MFSD2A,REPS2,ARHGAP19,GPR37L1,HEPACAM,NOMO2,NEGR1,CPT1C,A2ML1,DNAJC12,BEST1,COL9A2,NECAB2,NXPH1,PTPA,TENM4,PHACTR3,SDC3,RAB39A,PRKCG,PKN2,USP54,PUM1,WBP1L,RIMS3,C1orf109,TMCC2,FAM66C,RASGRF1,DBX2,DTNA,BSDC1,CRTAC1,ZNF248,CBLN2,SLC4A10,ELAVL4,YY1AP1,OLIG2" MicroRNA hsa-miR-4294:mirSVR_lowEffct hsa-miR-4294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.54E-27 1.37E-23 1.71E-26 1.57E-25 78 1380 "MDM4,TOMM40L,UNC79,TRIM46,CDC42BPA,PPFIA1,PKP4,GPAM,ZCCHC17,CACHD1,ST3GAL3,AQP4,ZNF365,SLC1A7,BCO1,RUFY2,DACH2,CAPRIN2,ASPH,TMEM108,ATP1A2,MYBPC1,SOX1,B3GALT2,ZSWIM8,ADAM15,NFASC,CASTOR3,POPDC3,KAZN,GNAS,ACSL6,CACNB2,PCDHGA3,CYB561A3,OLR1,MFSD2A,P2RX7,TMEM9,TLL2,ZFP91,SEZ6L,ARHGAP19,TPM4,PDE1A,PIRT,LINC01102,PLEKHB1,HEPACAM,FTO,BEST1,PPP2R5C,SNCAIP,ATRNL1,VCAN,PRKCG,NRSN1,RIMS3,DPYSL5,ANKS1B,DNAJC6,STMN4,PTPRE,C1orf109,SV2A,SRGAP3,PCDH15,KCNMA1,RALGDS,CAMK1G,VANGL2,RLBP1,SYT15,CACNG7,BSCL2,EPB41,LRRC23,RASGRP2" MicroRNA hsa-miR-15b*:mirSVR_highEffct hsa-miR-15b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-27 1.39E-23 1.73E-26 1.59E-25 80 1450 "EPS8,CSMD3,KLHL32,RTN1,SORCS1,ERMN,LINC00461,LRRC7,GOLGA7B,USP28,PPFIA1,ITSN1,SESN3,MAGI3,BCAS1,SHTN1,PAAF1,AQP4,SLC1A6,RUFY2,ASPH,CCDC181,MYBPC1,DCAF5,RGL1,PCDH11X,DDHD2,NODAL,UNC5D,ADGRL3,GPM6A,GPM6B,TCF7L2,PTBP2,CECR2,SYT6,CRB1,INA,GUCY1A2,PAH,CDC42,TPD52,MAGI1,SCRG1,CASC2,ZBED5,TMEFF2,JAM2,CADM1,CCSER2,ST8SIA5,PMP2,CP,MED1,FEZ2,PKN2,ANKS1B,CA10,PLPPR1,BDNF-AS,PRTFDC1,STMN4,OCIAD1,PTPRZ1,KCNMA1,NAV2,PEX5,DLG2,CAB39L,PID1,FAM66C,ABI1,GOPC,PAK5,SLC6A15,JMJD1C,ATL1,SEC61A2,LPAR6,EPB41L2" MicroRNA hsa-miR-376a:mirSVR_highEffct hsa-miR-376a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.72E-27 1.47E-23 1.83E-26 1.68E-25 71 1146 "RABEPK,MDM4,DSCAML1,SLC30A10,ANK2,DOCK10,APC,ASPH,SORCS3,RCOR3,PHYHIPL,MEGF11,IDI2-AS1,ADGRB2,SPART,DCAF5,SYT4,PSRC1,VXN,SYT6,GRIA4,GRIK2,INA,TJP1,KCNK10,CDC42,RBFOX2,TPD52,PDE3B,PRMT8,PDE4B,ZMYND8,TMEFF2,NRXN1,CCSER2,PMP2,BTF3L4,SPATA6,MFSD4A,CP,MED1,PPP3CB,KCNT2,ATRNL1,PRKACB,DOCK7,PKN2,EDRF1,MASP1,ANKS1B,PSMD13,PTHLH,COPS7A,CSDE1,OLFM3,OCIAD1,DNAH9,RAB5B,SLC17A6,PARP11,DPP6,PAK5,ABCC9,SLC6A15,ZYG11B,RFX4,JMJD1C,FAM135B,SIDT2,TMEM100,EPB41" MicroRNA hsa-miR-582-3p:mirSVR_highEffct hsa-miR-582-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.72E-27 1.48E-23 1.83E-26 1.68E-25 66 987 "SDE2,CNTNAP3,CLIP1,MAGI3,NLGN1,SHTN1,PAAF1,MIER1,ARHGAP5,DACH2,ASCL1,CSPG5,TMEM108,DKK3,GABBR1,CAB39,NMNAT2,ARPP21,C11orf87,CLASP2,DCAF5,RGL1,ARHGEF7,GPM6B,PTBP2,SYT6,NUMA1,GRIK2,GRIK4,GPR88,CDH10,TPM4,PCSK2,ZNF384,PDE4B,PDYN,CADM1,CAMKV,A2ML1,SPATA6,NSD2,CP,KCNT2,MICAL2,RBPJ,IGSF1,CTNND2,SPIRE1,SYNC,CA10,ELMO1,PRDM2,HP1BP3,CEP170,CSDE1,KCNA6,C1orf109,PTPRZ1,DLG2,KIF2A,KLRC2,GOPC,RGS7,ABI2,SLC4A10,EPB41L1" MicroRNA hsa-miR-651:mirSVR_highEffct hsa-miR-651:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-27 1.52E-23 1.88E-26 1.73E-25 69 1082 "CNTNAP3,RCSD1,ACTN2,MEG3,SLC25A25,SLITRK1,SORCS1,SCN3A,LRRTM4,LRRC7,FOXG1,PPFIA1,APBA2,NTNG1,MAGI3,GPAM,SLITRK3,AQP4,SLC2A5,CCDC88A,ASCL1,SPHKAP,BRINP2,SORCS3,DKK3,EMC1,SPART,CLASP2,AJAP1,NODAL,ZEB1,TMEM151B,VXN,GPR88,RBFOX2,TPM4,MAGI1,PDE1A,PDYN,BEST3,CADM1,VAV2,CNTN1,ATCAY,MED1,PPP3CB,RBPJ,FMN2,KIAA1755,PKN2,CTNND2,PUM1,MASP1,ANKS1B,SYNC,LRRTM3,ELMO1,PRDM2,OLFM3,KCNK2,GOPC,GNE,PAK5,SLC6A15,INSYN2,ARHGAP12,SLC4A10,ELAVL3,UEVLD" MicroRNA hsa-miR-562:mirSVR_lowEffct hsa-miR-562:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.81E-27 1.52E-23 1.89E-26 1.73E-25 84 1595 "ACER3,EYA1,IL17D,WLS,CLIP1,SORCS1,TUBB4A,FGF14,HPCAL4,SOX6,USP28,ANXA7,NTNG1,SORBS1,NLGN1,PAAF1,ZNF365,SNAP25,NRG3,SON,GAD2,JPH4,B4GALNT1,FXYD6,NPAS3,NCAM1,STOX1,INKA2,GJB1,NEUROD1,SLCO1C1,SYT4,CAMTA1,UNC5D,KLHL4,PRUNE2,GPM6A,ACSL6,NUDT21,PAH,HPS5,CDC42,CDH8,PDE4B,CASC2,TMEFF2,ARHGAP22,CAMKV,NOMO2,CCSER2,DNAJC12,FTO,NXPH1,CNRIP1,CHD1L,SF1,SNCAIP,PPP3CB,KCNT2,FEZ1,PHACTR3,RAB39A,USP54,BRINP3,DPYSL5,SPIRE1,ZC3H11A,PTPRO,KCNK1,DLG2,KLRC3,PLEKHB2,DPP6,SLC25A18,DTNA,SLC6A15,ZYG11B,RFX4,FAM135B,RPRD1A,ABI2,TMEM100,EPB41L1,LRRC23" MicroRNA hsa-let-7c*:mirSVR_highEffct hsa-let-7c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.21E-27 1.74E-23 2.15E-26 1.97E-25 65 959 "DPF1,TMEM74,MDM4,CSMD3,GALNT13,ADD3,FCGR1A,FCGR1B,GPR158,LRRC7,FGF14,SEMA6A,PPFIA1,ITSN1,SH3GL2,MIER1,ASPH,SORCS3,ATM,FYN,CADM3,SOX10,ARPP21,IDI2-AS1,NCAM1,CLASP2,SMOC1,ERBIN,GLS,CAMSAP2,KLHL4,CACNB2,GRIA1,GRID1,OMG,ZFP91,CDH10,BEST3,HMGB1,MS4A7,SULT4A1,SPATA6,SLC36A4,POU3F2,OSBPL3,NCAN,PHACTR3,PRKACB,PUM1,NOS1AP,KIAA0408,ZNF385B,PTHLH,CEP170,MAGI2,ZC3H11A,OLFM3,OCIAD1,PTPRD,SV2A,FAM13C,SLC6A15,SEC61A2,SH3GLB1,VWA5A" MicroRNA hsa-miR-33a:mirSVR_highEffct hsa-miR-33a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.23E-27 1.75E-23 2.16E-26 1.98E-25 66 990 "SLC25A25,LINC00461,FGF14,UNC79,AMPH,ERICH3,CDC42BPA,USP28,SH3GL2,SLITRK3,ZNF365,SLC1A6,MSR1,SLC14A1,ASCL1,SLCO1A2,SORCS3,DKK3,B3GALT2,ENKUR,SALL3,KIF1B,NAP1L2,NCAM1,COLGALT2,NDUFA5,ZNF302,TBX15,ZEB1,PTBP2,GRIK2,GPR88,CRB1,AIFM1,LGI1,TPM3,PDE3B,LINC01102,GDAP1L1,CADM1,NOMO2,SPATA6,PPP3CB,RGS6,MICAL2,VCAN,DZIP3,FMN2,NRSN1,PROX1,MASP1,PTHLH,PRDM2,PRTFDC1,KCNA4,PLPPR4,PTPRZ1,SLC17A6,ABI1,GOPC,FAM13C,DTNA,SLC6A15,RBM12,SLC4A10,EN2" MicroRNA hsa-miR-708*:mirSVR_lowEffct hsa-miR-708*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.50E-27 1.90E-23 2.34E-26 2.15E-25 78 1387 "ZFYVE27,ASIC1,ACTN2,ATAT1,CSMD3,TESK2,LRRTM4,FGF1,SOX6,USP28,ITSN1,ANXA7,SH3GL2,DOCK10,CACHD1,ST3GAL3,API5,ZNF365,ARHGAP5,ARFGAP2,SLC14A1,ARFGAP1,ATM,ATP2B2,SCN3B,MYT1L,TNIK,ZCCHC24,JPH4,EMC1,DNER,C11orf87,HEPN1,ZNF638,NODAL,CAMSAP2,ADGRL3,CACNB2,PTBP2,OPCML,TIE1,TPD52,TPM3,PDE3B,HEPACAM,SERPINE2,NEGR1,TJP2,PMP2,RGS6,VCAN,DZIP3,FMN2,PUM1,EDRF1,WBP1L,DNAJC6,PMEPA1,MAGI2,OCIAD1,KCNA6,PLPPR4,KCNJ10,CCDC3,ARNT2,KCNMA1,NAV2,DLG2,KIF2A,HS3ST4,ABCC9,SLC6A15,RET,SEC61A2,SLC39A12,SLC4A10,BSCL2,SEZ6" MicroRNA hsa-miR-31:mirSVR_highEffct hsa-miR-31:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.55E-27 1.92E-23 2.37E-26 2.17E-25 62 870 "ATAT1,ARID1A,FCGR1A,TESK2,AGT,ASIC4,ELMOD1,MOBP,TRIM46,USP28,TACC2,ST3GAL3,RPH3A,SLC8A3,B3GAT1,GABBR1,MYT1L,TNIK,CAB39,AHCYL1,DNER,LMO3,C11orf87,CLASP2,ZNF302,PHLDB1,POPDC3,KAZN,FAM69C,TCF12,GPR88,CRB1,PTPN5,INA,PC,TNS1,ZNF384,LINC01102,FNDC5,BEST3,ASIC3,GDAP1L1,A2ML1,TJP2,SLC25A27,TENM4,MICAL2,PRKACB,CTNND2,EDRF1,SYNC,ITGAV,OCIAD1,KCNA6,KCNK2,PEX5,RAB5B,DPP6,RET,FAM135B,ZNF248,C2orf80" MicroRNA hsa-miR-382:mirSVR_highEffct hsa-miR-382:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.67E-27 1.99E-23 2.45E-26 2.24E-25 78 1388 "PRR5L,ZFYVE27,LGR4,RCSD1,EYA1,ARID1A,KLHL32,GALNT13,SORCS1,ERMN,SNX32,SCN3A,KIAA1109,BCAR3,PKP4,MAGI3,GPAM,SYBU,BCAS1,API5,SHTN1,MIER1,PDE8B,SPHKAP,CAPRIN2,SORCS3,ATP1A2,EIF4G3,SOX5,ENKUR,KIF1B,NPAS3,ARHGEF7,SYT4,DCLK2,CAMTA1,TMEM136,ANO4,TMEM151B,GRIA2,CRB1,TGFBR3,USP2,PCDH9,CDH10,BEST3,CADM1,NEGR1,UBTF,A2ML1,OPALIN,PMP2,CELF5,SLC25A27,NXPH1,CNRIP1,CP,CHD1L,CTNND2,PUM1,TOX,PLPPR5,SYNC,LRRTM3,OLFM3,PTPRD,PTPRE,SLC17A6,FAM66C,GOPC,SLC6A15,ZYG11B,INSYN2,SEC61A2,SLC4A10,EN2,RCAN2,SEZ6" MicroRNA hsa-miR-128:mirSVR_highEffct hsa-miR-128:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.87E-27 2.09E-23 2.58E-26 2.36E-25 69 1088 "MDM4,F3,AMER2,FCGR1A,FGF1,SFPQ,ITSN1,PPM1E,APBA2,NTNG1,GPAM,CCDC88A,PDE8B,ASPH,RCOR3,ALDH4A1,SNAP25,MEGF11,WDTC1,KIF21B,GAD2,ENKUR,ARPP21,TTLL9,NAP1L2,NPAS3,CLASP2,COLGALT2,ADHFE1,SEPT3,ZNF638,CAMTA1,UNC5D,ZEB1,PTBP2,CECR2,GRIA1,GRIK3,CRB1,TMEM25,PAH,PCDH9,MAGI1,CIART,TLX1,TJP2,CABP1,BEST1,RNF14,VCAN,NCAN,PLPP4,ECE2,PTCH1,CA10,MAGI2,CDH20,SMG7,SRGAP3,KCNK2,KCNMA1,NAV2,FAM66C,DTNA,RTN4,RET,ZNF248,VANGL2,ARHGAP12" MicroRNA hsa-miR-486-5p:mirSVR_lowEffct hsa-miR-486-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.95E-27 2.14E-23 2.63E-26 2.41E-25 77 1355 "ZFYVE27,MAP6,ACTN2,EYA1,ATAT1,CSMD2,ARID1A,WAC,SORCS1,ELMOD1,SOX6,CDC42BPA,ANK1,PPFIA1,ITSN1,PKP4,APC,MAGI3,TACC2,CACHD1,ST3GAL3,JAKMIP3,MADD,MSR1,CCDC88A,CAPRIN2,SON,CAB39,ALDH1L1,GLS,ADGRL3,ANO4,ATF7,ACSL6,TCF7L2,ZEB1,PTBP2,EML4,GRIA4,CRB1,USP2,ZDHHC22,LGI1,TPM3,MAGI1,ZMYND8,HMGB1,ZFYVE9,UBTF,DNAJC12,CNTN1,C11orf49,PRRX1,SLC36A4,FAT3,NXPH1,PPP2R5C,RGS6,ATRNL1,PRKCG,USP54,PSD,ZNF385B,LRRTM3,PMEPA1,HP1BP3,CEP170,PTPRD,PLPPR4,KCNMA1,ABI1,DTNA,ZYG11B,JMJD1C,EFNA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-127-5p:mirSVR_highEffct hsa-miR-127-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-27 2.16E-23 2.65E-26 2.43E-25 67 1025 "ACLY,RBM10,SYT9,ADGRV1,CSMD3,SLITRK1,FCGR1A,DRAXIN,LINC00461,SFPQ,SGIP1,ITSN1,DOCK10,DGKZ,PAAF1,CADPS,PDE8B,SPHKAP,ASPH,SLN,RCOR3,ILDR2,AHCYL1,B4GALNT1,NEK6,FXYD6,NPAS3,SPART,RGL1,ADHFE1,NEUROD1,ACSBG1,PCDH11X,ZNF638,SYT4,CAMSAP2,PSRC1,CAMK2G,OMG,TLL2,PAH,TNR,PDE3B,LINC01102,BEST3,CAMKV,UBTF,BTF3L4,CP,CHD1L,PUM1,EDRF1,PTHLH,CADM2,COPS7A,MAGI2,STMN4,BLOC1S6,PTPRE,PTPRO,KCNK2,PCDH15,PID1,JMJD1C,RGS7,GPR61,RAVER2" MicroRNA hsa-miR-3189:mirSVR_lowEffct hsa-miR-3189:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.71E-27 2.55E-23 3.13E-26 2.87E-25 83 1571 "ABAT,MAP6,SYT9,ADGRV1,LDLRAD3,WLS,ADAR,KLHL32,TOMM40L,TESK2,FGF1,FGF14,ASIC4,SLC30A10,MOBP,FOXG1,TRIM46,SELL,ITSN1,PPM1E,SORBS1,ST3GAL3,AQP4,MIER1,LRRC55,ASPH,SLN,BRINP2,TMEM108,EIF4G3,WDTC1,EMC1,TTLL9,ADGRB2,GJB1,SEPT3,ARHGEF7,CASTOR3,ANO4,GPR19,TCF12,VXN,NUMA1,GRIK2,VWCE,CRB1,USP2,ZDHHC22,ZFP91,PADI2,PCDH9,LGI1,ZNF384,HPCA,CCSER2,ST8SIA5,PRRX1,NECAB2,PNKD,TENM4,NKAIN4,MICAL2,RBPJ,FAM131B,MASP1,PSD,TOX,WBP1L,SYTL2,BDNF-AS,CEP170,PTPRZ1,SRGAP3,PID1,FAM66C,DTNA,BSDC1,NUP214,RLBP1,SEC61A2,RNF220,CBLN2,TMEM100" MicroRNA hsa-miR-190b:mirSVR_highEffct hsa-miR-190b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.06E-27 2.74E-23 3.35E-26 3.08E-25 68 1061 "CNTNAP3,KLHL32,SLITRK1,LINC00461,FGF14,GPAM,SORBS1,NLGN1,ZNF365,MIER1,SLC14A1,ASTN1,RCOR3,C10orf105,NRG3,PHYHIPL,TNIK,CAB39,ARPP21,SALL3,DNER,RGL1,NEUROD1,RND1,PCDH11X,DCLK2,ANO4,PRUNE2,ZEB1,GRIA4,GRIK3,CRB1,PAX6,CDC42,PCDH9,PDE3B,ZMYND8,CHRM1,CADM1,NRXN1,NEGR1,BTF3L4,COL9A2,MED1,PPP2R5C,RBPJ,DZIP3,PLD5,PLPPR5,CA10,BDNF-AS,PTHLH,PRDM2,CSDE1,MAGI2,BLOC1S6,KCNA4,PLPPR4,AK5,PCDH15,C12orf4,SUSD4,DTNA,ABCC9,ZYG11B,RBM12,RPRD1A,BAALC" MicroRNA hsa-miR-1284:mirSVR_highEffct hsa-miR-1284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.31E-27 2.88E-23 3.52E-26 3.23E-25 71 1159 "EPS8,MAP6,ADGRV1,LDLRAD3,CSMD3,F3,ANK1,ITSN1,NTNG1,SLITRK3,SORBS1,MSR1,LRRC55,ARFGAP2,SMARCE1,ATP2B2,USP33,B3GALT2,NASP,SPART,NCAM1,SMOC1,ERBIN,AJAP1,VAMP1,ZNF638,CAMTA1,NODAL,UNC5D,WWC1,CNDP1,ANO4,ACSL6,CACNB2,TGFBR3,CDC42,PCDH8,TPD52,PCSK2,ZNF384,PDE1C,PDE4B,HMGB1,HPSE2,PLEKHB1,CASC2,TMEFF2,NRXN1,SLC25A27,ACBD5,CRLS1,PPP2R5C,PPP3CB,FEZ1,VCAN,PTCH1,PTHLH,CSDE1,ZC3H11A,KCNC1,NTM,AK5,DLG2,RTN4,SLC6A15,FAM135B,RPRD1A,ARHGAP12,ROM1,TMEM100,EPB41L2" MicroRNA hsa-miR-361-5p:mirSVR_highEffct hsa-miR-361-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.92E-27 3.20E-23 3.91E-26 3.59E-25 75 1295 "LGR4,RTN3,ADGRV1,MDM4,NDRG2,ADD3,SORCS1,ERMN,ADORA1,LINC00461,FGF1,ELMOD1,FOXM1,ASRGL1,PKP4,NTNG1,BCAS1,CCDC88A,DACH2,SON,MYT1L,DCAF5,RGL1,ADHFE1,ARHGEF7,GLS,RHBDL3,PCDH11X,ZNF638,GOLGB1,GPM6A,CACNB2,ZEB1,GRIA4,CRB1,PCDH9,RBFOX2,MAGI1,PDE4B,SERPINE2,PMP2,CRLS1,SNCAIP,PPP3CB,RGS6,ATRNL1,RBPJ,PRKACB,FMN2,USP54,CTNND1,CTNND2,MAPK8,WBP1L,SYTL2,PLPPR5,ITGAV,PRDM2,MAGI2,KCNA2,NTM,AK5,PCDH15,PEX5,CAB39L,KLRC2,PARP11,FAM13C,ZYG11B,JMJD1C,SYT15,SEC61A2,ABI2,ROM1,RCAN2" MicroRNA hsa-miR-3115:mirSVR_lowEffct hsa-miR-3115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.42E-27 3.47E-23 4.24E-26 3.89E-25 65 971 "EPS8,ACER3,MBP,ATAT1,SLITRK1,FABP7,CHST15,SCN3A,BBOX1,GOLGA7B,ELMOD1,MOBP,ERICH3,SYBU,ZNF365,MADD,NSG2,SLC14A1,CADPS,SCMH1,SMARCE1,ATM,ATP1A2,GAD2,ARPP21,SALL3,NAP1L2,RGL1,KAZN,NUDT21,CAMK2G,GRIA2,GRID1,INA,NEURL1,PAH,TPM3,PDYN,TUB,HNRNPK,TLX1,NLGN3,FADS2,FTO,PRRX1,FAT3,CHD1L,SNCAIP,DOCK7,DZIP3,PRKCZ,MAPK10,SYNC,SIRPA,OLFM3,PTPRE,KCNJ10,PCDH15,KCNMA1,KCNN3,FAM13C,RFX4,VANGL2,TMEM100,RCAN2" MicroRNA hsa-miR-3194:mirSVR_lowEffct hsa-miR-3194:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.51E-27 3.52E-23 4.29E-26 3.94E-25 80 1471 "TTYH1,CDHR1,SYT9,SYNDIG1,ADGRV1,KCNIP2,NDRG2,RTN1,FABP7,FCGR1A,HOGA1,SCN4B,FGF1,ASIC4,FGR,HPCAL4,USP28,CNIH2,SH3GL2,NTNG1,NLGN1,ST8SIA1,RPH3A,ARFGAP2,DACH2,SCMH1,KBTBD12,TMEM108,ATP1A3,TNIK,ZSWIM8,ADAM15,NASP,NCDN,KIRREL3,RND1,MMD2,CACNA1E,AKNA,VWCE,OPCML,AIFM1,TLL2,TPM3,ZNF384,TMPRSS5,CHI3L2,PHKG1,PLXNB3,C11orf49,MFSD4A,CRLS1,PTPA,SNCAIP,RGS6,NKAIN4,ATRNL1,RBPJ,PRKACB,SDC3,ARHGEF4,NRSN1,NOS1AP,MASP1,TOX,LRRTM3,KCNJ10,KCNJ11,KCNMA1,NKAIN1,WIPF2,RALGDS,SLC25A18,SUSD4,CAMK1G,NUP214,ARHGEF10L,SYT15,SIDT2,LMO1" MicroRNA hsa-miR-545:PITA hsa-miR-545:PITA_TOP PITA 6.79E-27 3.68E-23 4.47E-26 4.11E-25 54 653 "EPS8,GALNT13,LRRC7,CDC42BPA,ANK3,PPM1E,DOCK10,NTNG1,SLITRK3,TACC2,SORBS1,SNAP25,PALLD,SON,MYT1L,KIF21B,CAB39,ILDR2,BCL2L2,CAMTA1,CDK5R2,ADGRL3,CACNA1E,HAP1,CAMK2A,CAMK2G,GRIA4,TMEM25,INA,ZFP91,DCLK1,TPM4,PDE3B,HNRNPK,SERPINE2,CADM1,PPP3CB,NCAN,CTNND2,TOX,KIAA0513,PTCH1,CA10,CEP170,OLFM3,PTPRD,KCNA6,SMG7,TMEM255A,DBX2,TTLL7,ARHGAP12,ELAVL3,RCAN2" MicroRNA hsa-miR-1246:mirSVR_highEffct hsa-miR-1246:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.15E-27 3.87E-23 4.71E-26 4.32E-25 74 1265 "RTN3,WLS,ADAR,RTN1,WAC,SCN3A,FGF14,SEMA6A,ERICH3,ANK2,APC,NTNG1,BCAS1,MIER1,MSR1,CCDC88A,SLCO1A2,SMARCE1,PHYHIPL,KIF21B,CPLX2,NCAM1,CLASP2,BCL2L2,NDUFA5,ZNF302,AJAP1,ARHGEF7,GLS,VAMP1,LUZP2,ADGRL3,GOLGB1,ANO4,ZEB1,CAMK2G,GRIA1,GRIA4,RFFL,GRIK2,ADAMTS8,CCKBR,TMEM257,PCDH9,TPD52,PDYN,CADM1,NRXN1,DNAJC12,MEAF6,SLC25A27,PRRX1,DOCK7,CTNND1,MASP1,WBP1L,ZNF385B,PTCH1,ITGAV,CEP170,MAGI2,OCIAD1,SMG7,DNAH9,SLC25A48,PLEKHB2,ABI1,FAM13C,ZYG11B,RFX4,JMJD1C,FAM135B,SEC61A2,ABI2" MicroRNA hsa-miR-653:mirSVR_lowEffct hsa-miR-653:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.34E-27 3.98E-23 4.83E-26 4.43E-25 91 1880 "SERPINA3,RCSD1,WLS,MDM4,CSMD3,TOMM40L,TESK2,BCAR3,AMPH,ANXA7,NTNG1,ST3GAL3,LRRC4C,SHTN1,SLC7A14,CSPG5,TAGLN3,BRINP2,TMEM108,NRG3,ATP2B2,SON,KIF21B,GAD2,NMNAT2,JPH4,ARPP21,KIF1B,NAP1L2,NFASC,ZNF302,SEPT3,GLS,ZNF638,UNC5D,WWC1,TMEM136,VWC2,CACNB2,PTBP2,NUDT21,CRB1,TLL2,MAEL,PAX6,PC,PCDH9,CDH8,DCLK1,TPD52,PDE3B,HMGB1,ANO5,TMEFF2,CAMKV,ST8SIA5,CNTN1,NSD2,SF1,KCNT2,MICAL2,PLD5,IGSF1,PUM1,ANKS1B,GON4L,SPIRE1,TOMM20,PLPPR5,ZNF385B,PSMD13,CA10,PTPRE,KCNK2,NAV2,OLIG1,SLC17A6,PLEKHB2,GNE,FAM13C,DTNA,RGS10,INSYN2,SH3GLB1,RPRD1A,ELAVL4,C2orf80,OLIG2,EPB41,UEVLD,BAALC" MicroRNA hsa-miR-3200:mirSVR_lowEffct hsa-miR-3200:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.38E-27 4.00E-23 4.85E-26 4.45E-25 68 1068 "ABAT,ZFYVE27,SYT9,MDM4,KLHL32,NLGN4X,FCGR1A,KIAA1109,FGF1,LRRC7,HPCAL4,PPFIA1,BCAS1,SHTN1,MIER1,MSRA,ARFGAP2,SLCO1A2,EIF4G3,MYT1L,ARPP21,TTLL9,GLS,PRUNE2,FAM69C,CACNA1E,CACNB2,TCF7L2,CLEC9A,TCF12,EML4,GRIA2,GRIA4,RFFL,GRM3,ATP13A2,TF,PTPN5,USP2,AIFM1,REPS2,PDE1A,ZMYND8,CASC2,HEPACAM,NRXN1,NMT2,PMP2,NSD2,CP,CRLS1,RGS6,ECE2,ANKS1B,JAKMIP2,PRDM2,OCIAD1,PTPRD,KCNJ9,KCNJ10,TMCC2,KCNK2,HS3ST4,PARP11,SUSD4,DTNA,EEF1A2,SYT15" MicroRNA hsa-miR-4310:mirSVR_highEffct hsa-miR-4310:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.41E-27 4.01E-23 4.86E-26 4.45E-25 76 1334 "PRR5L,SYNDIG1,GALNT13,WAC,ERMN,LRRTM4,LRRC7,CDC42BPA,CNIH2,PPM1E,MAGI3,GPAM,NLGN1,BCAS1,SHTN1,PAAF1,CCDC88A,ASPH,RCOR3,EIF4G3,MEGF11,SON,SOX1,MYT1L,CAB39,AHCYL1,CPLX2,NPAS3,LMO3,CLASP2,NDUFA5,DCAF5,ADHFE1,OS9,KAZN,CAMTA1,CAMSAP2,ADGRL3,GPM6A,VWC2,TCF7L2,VSTM2A,GRIA2,GRIA4,TJP1,CDC42,TPM3,PRMT8,CASC2,HNRNPK,BTF3L4,SNCAIP,OSBPL3,VCAN,RBPJ,PRKAB2,PRKACB,DOCK7,DZIP3,MASP1,JAKMIP2,CADM2,CEP170,PTPRO,KCNJ11,PARP11,ABI1,BSDC1,ZYG11B,RET,RFX4,FAM135B,ATL1,RBM12,SLC4A10,RCAN2" MicroRNA hsa-miR-4305:mirSVR_lowEffct hsa-miR-4305:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.71E-27 4.18E-23 5.05E-26 4.63E-25 69 1101 "EYA1,PNMA8B,AMER2,SLC44A5,TESK2,BCAR3,BBOX1,GOLGA7B,SFPQ,ANK3,ITSN1,ST3GAL3,AQP4,SLC1A7,SLC2A5,MSR1,SORCS3,SMARCE1,EIF4G3,FYN,GABBR1,NPAS3,C11orf87,COLGALT2,RCOR2,RGL1,ADHFE1,KAZN,ZEB1,PTBP2,CELF3,TNFRSF1B,TPD52,PRMT8,GPR37L1,HMGB1,SCRG1,SERPINE2,TJP2,BEST1,PRRX1,MED1,CRLS1,MICAL2,ATRNL1,PRKACB,DZIP3,FMN2,CTNND2,PUM1,KIAA0408,BRINP3,DPYSL5,LRP8,ZC3H11A,KCNA1,PTPRE,NTM,KCNJ11,KIF2A,PLEKHB2,ABI1,ATN1,DSCAM,PAK5,ATL1,ARHGAP12,TMEM100,EPB41L2" MicroRNA hsa-miR-3190-5p:mirSVR_highEffct hsa-miR-3190-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.99E-27 4.87E-23 5.88E-26 5.39E-25 64 946 "CDHR1,SRARP,ATAT1,ARID1A,TMEM156,ADORA3,TESK2,MOBP,MOG,TRIM46,SELL,ANK3,CNIH2,ITSN1,CCDC80,NLGN1,STK32C,MSR1,SCG3,NAXD,SORCS3,TMEM108,ATP2B2,DKK3,GAD2,KIF1B,NPAS3,NFASC,ADHFE1,RND1,VAMP1,PCDH11X,ZNF638,GNAS,GNG3,ANO4,LRIT2,NPPA,CACNB2,ZEB1,CLEC9A,VSTM2A,P2RX7,TNR,PCDH8,LGI1,PDE1C,PRMT8,GDAP1L1,BTF3L4,IFFO1,CHD1L,MED1,KCNT2,OSBPL3,EDRF1,PRDM2,MAGI2,SV2A,AK5,KCNK1,RERGL,VWA5A,SLC4A10" MicroRNA hsa-let-7d:mirSVR_lowEffct hsa-let-7d:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.94E-27 5.38E-23 6.49E-26 5.96E-25 88 1774 "RABEPK,ACER3,CDHR1,DUSP27,MEG3,GALNT13,SORCS1,TUBB4A,CHST15,TOMM40L,SNX32,SCN4B,ASIC4,ANK1,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,RPH3A,RUFY2,MSR1,SLC8A2,SLCO1A2,C10orf105,USP33,B3GALT2,ZSWIM8,ADAM15,NPAS3,NFASC,NDUFA5,STOX1,NELL1,MLC1,GOLGB1,ATF7,GPR26,PTBP2,NUMA1,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,TPM3,LINC01102,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,BLOC1S6,PTPRD,KCNC1,RABGAP1L,KCNJ10,TMCC2,ATG16L1,DSCAM,RASGRF1,BSDC1,SLC6A15,NUP214,ELAVL4,EPB41L2" MicroRNA hsa-miR-548a-3p:PITA hsa-miR-548a-3p:PITA_TOP PITA 1.03E-26 5.58E-23 6.73E-26 6.17E-25 60 828 "CSMD3,RTN1,ADCY2,NLGN4X,LRRC7,AMPH,CDC42BPA,NLGN1,CCDC88A,DACH2,B3GAT1,WDTC1,SOX1,MYT1L,ZCCHC24,LMO3,CLASP2,ERBIN,RGL1,NFIA,ARHGEF7,GLS,SYT4,DCLK2,CAMTA1,CAMSAP2,WWC1,ZEB1,PTBP2,PTPN5,TGFBR3,CDH10,TUB,NRXN2,NEGR1,CCSER2,NSD2,ACBD5,POU3F2,CRMP1,ATRNL1,CTNND2,BRINP3,TOMM20,LRRTM3,PTCH1,CA10,PMEPA1,CSDE1,ZC3H11A,SNX27,KIF2A,RAB5B,PID1,GOPC,DSCAM,ZYG11B,RBM12,ABI2,EPB41L1" MicroRNA hsa-miR-301a:PITA hsa-miR-301a:PITA_TOP PITA 1.13E-26 6.10E-23 7.30E-26 6.70E-25 53 633 "ASIC1,CLIP1,RTN1,ADCY2,GPR158,TESK2,SCN3A,USP28,API5,MIER1,CCDC88A,CAPRIN2,SNAP25,ATP2B2,MYT1L,SOX5,SMOC1,ERBIN,NEUROD1,CAMTA1,CAMSAP2,NUMA1,ZFP91,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,PFKFB3,CCSER2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,ARHGEF4,NRSN1,PSD,PMEPA1,LRP8,CEP170,MAGI2,PTPRD,KCNJ10,SNX27,DLG2,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-301b:PITA hsa-miR-301b:PITA_TOP PITA 1.13E-26 6.10E-23 7.30E-26 6.70E-25 53 633 "ASIC1,CLIP1,RTN1,ADCY2,GPR158,TESK2,SCN3A,USP28,API5,MIER1,CCDC88A,CAPRIN2,SNAP25,ATP2B2,MYT1L,SOX5,SMOC1,ERBIN,NEUROD1,CAMTA1,CAMSAP2,NUMA1,ZFP91,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,PFKFB3,CCSER2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,ARHGEF4,NRSN1,PSD,PMEPA1,LRP8,CEP170,MAGI2,PTPRD,KCNJ10,SNX27,DLG2,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-130a:PITA hsa-miR-130a:PITA_TOP PITA 1.13E-26 6.10E-23 7.30E-26 6.70E-25 53 633 "ASIC1,CLIP1,RTN1,ADCY2,GPR158,TESK2,SCN3A,USP28,API5,MIER1,CCDC88A,CAPRIN2,SNAP25,ATP2B2,MYT1L,SOX5,SMOC1,ERBIN,NEUROD1,CAMTA1,CAMSAP2,NUMA1,ZFP91,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,PFKFB3,CCSER2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,ARHGEF4,NRSN1,PSD,PMEPA1,LRP8,CEP170,MAGI2,PTPRD,KCNJ10,SNX27,DLG2,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-130b:PITA hsa-miR-130b:PITA_TOP PITA 1.13E-26 6.10E-23 7.30E-26 6.70E-25 53 633 "ASIC1,CLIP1,RTN1,ADCY2,GPR158,TESK2,SCN3A,USP28,API5,MIER1,CCDC88A,CAPRIN2,SNAP25,ATP2B2,MYT1L,SOX5,SMOC1,ERBIN,NEUROD1,CAMTA1,CAMSAP2,NUMA1,ZFP91,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,PFKFB3,CCSER2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,ARHGEF4,NRSN1,PSD,PMEPA1,LRP8,CEP170,MAGI2,PTPRD,KCNJ10,SNX27,DLG2,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-454:PITA hsa-miR-454:PITA_TOP PITA 1.13E-26 6.10E-23 7.30E-26 6.70E-25 53 633 "ASIC1,CLIP1,RTN1,ADCY2,GPR158,TESK2,SCN3A,USP28,API5,MIER1,CCDC88A,CAPRIN2,SNAP25,ATP2B2,MYT1L,SOX5,SMOC1,ERBIN,NEUROD1,CAMTA1,CAMSAP2,NUMA1,ZFP91,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,PFKFB3,CCSER2,ST8SIA5,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,ARHGEF4,NRSN1,PSD,PMEPA1,LRP8,CEP170,MAGI2,PTPRD,KCNJ10,SNX27,DLG2,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12,EPB41L1" MicroRNA hsa-miR-548f:PITA hsa-miR-548f:PITA_TOP PITA 1.17E-26 6.33E-23 7.58E-26 6.95E-25 60 830 "CSMD3,RTN1,ADCY2,NLGN4X,LRRC7,AMPH,CDC42BPA,NLGN1,CCDC88A,DACH2,B3GAT1,WDTC1,SOX1,MYT1L,ZCCHC24,LMO3,CLASP2,ERBIN,RGL1,NFIA,ARHGEF7,GLS,SYT4,DCLK2,CAMTA1,CAMSAP2,WWC1,ZEB1,PTBP2,PTPN5,TGFBR3,CDH10,TUB,NRXN2,NEGR1,CCSER2,NSD2,ACBD5,POU3F2,CRMP1,ATRNL1,CTNND2,BRINP3,TOMM20,LRRTM3,PTCH1,CA10,PMEPA1,CSDE1,ZC3H11A,SNX27,KIF2A,RAB5B,PID1,GOPC,DSCAM,ZYG11B,RBM12,ABI2,EPB41L1" MicroRNA hsa-miR-101-3p.2:TargetScan hsa-miR-101-3p.2 TargetScan 1.19E-26 6.43E-23 7.68E-26 7.05E-25 59 801 "EPS8,ACER3,ARID1A,FOXG1,ANK3,PPFIA1,ITSN1,APC,NTNG1,MAGI3,JAKMIP3,MIER1,ATP2B2,ARPP21,NPAS3,NFASC,LMO3,GFRA1,RGL1,NEUROD1,AJAP1,FAM168A,CAMSAP2,GOLGB1,ACSL6,CACNB2,CECR2,BRSK2,GRIA2,GRIK2,PTPN5,INA,CD81,CDH8,MAGI1,HNRNPK,DLGAP3,CADM1,PRRX1,FAT3,NXPH1,FMN2,PKN2,MAPK8,PROX1,PTCH1,JAKMIP2,PTHLH,RGMA,MAGI2,KCNA1,CDH20,KCND3,KCNN3,PEX5,KIF2A,RASGRF1,ABI2,PRRT4" MicroRNA hsa-miR-346:mirSVR_lowEffct hsa-miR-346:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-26 6.81E-23 8.13E-26 7.46E-25 70 1143 "MAP6,MEG3,EYA1,MRVI1,FABP7,SNX32,DISP3,FGF14,PDZD4,PPFIA1,SLITRK3,ST3GAL3,BCAS1,PKNOX2,MT3,CGREF1,ALDH4A1,DKK3,SPART,NFASC,NCDN,NELL1,ZNF638,SEMA4A,GNAS,NODAL,MMD2,ADGRL3,KLHL4,ATF7,NEU4,TCF7L2,PTBP2,EML4,VXN,BRSK2,RFFL,ADAMTS8,CRB1,REPS2,PFKFB3,CASC2,MS4A7,HEPACAM,UBTF,OPALIN,TJP2,ETNPPL,VCAN,PRKAB2,DOCK7,RAB39A,NRSN1,HES5,FAM131B,MASP1,BDNF-AS,CEP170,CDH20,KCNJ9,PCDH15,DLG2,KLRC3,RAP1GAP,SUSD4,DTNA,SLC6A15,RET,INSYN2,BSCL2" MicroRNA "TTTGCAC,MIR-19B:MSigDB" "TTTGCAC,MIR-19B:MSigDB" MSigDB 1.35E-26 7.33E-23 8.73E-26 8.00E-25 47 483 "PRR5L,RIMKLA,F3,RTN1,TESK2,SOX6,ITSN1,ANXA7,SYBU,SHTN1,MIER1,ARHGAP5,CCDC88A,SHANK2,ATP2B2,USP33,SOX5,CAB39,SPART,SMOC1,RGL1,NEUROD1,CAMTA1,ZFP91,PFKFB3,ZFYVE9,CCSER2,BTF3L4,ACBD5,POU3F2,PSD,WBP1L,DPYSL5,SPIRE1,PMEPA1,CEP170,MAGI2,KCNA4,SV2A,SRGAP3,SNX27,RAB5B,ATG16L1,ST8SIA3,RFX4,ARHGAP12,CBLN2" MicroRNA "TTTGCAC,MIR-19A:MSigDB" "TTTGCAC,MIR-19A:MSigDB" MSigDB 1.35E-26 7.33E-23 8.73E-26 8.00E-25 47 483 "PRR5L,RIMKLA,F3,RTN1,TESK2,SOX6,ITSN1,ANXA7,SYBU,SHTN1,MIER1,ARHGAP5,CCDC88A,SHANK2,ATP2B2,USP33,SOX5,CAB39,SPART,SMOC1,RGL1,NEUROD1,CAMTA1,ZFP91,PFKFB3,ZFYVE9,CCSER2,BTF3L4,ACBD5,POU3F2,PSD,WBP1L,DPYSL5,SPIRE1,PMEPA1,CEP170,MAGI2,KCNA4,SV2A,SRGAP3,SNX27,RAB5B,ATG16L1,ST8SIA3,RFX4,ARHGAP12,CBLN2" MicroRNA hsa-miR-148b:mirSVR_highEffct hsa-miR-148b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.46E-26 7.92E-23 9.42E-26 8.64E-25 71 1179 "PRR5L,RTN3,FAM43B,RTKN,F3,FCGR1A,LRRTM4,FGF14,SFPQ,USP28,APBB1,NTNG1,MIER1,SLC1A7,RUFY2,ASPH,ATP1A2,DKK3,USP33,SOX5,DNER,SMOC1,RGL1,NEUROD1,SYT4,DDHD2,UNC5D,GPM6A,ZEB1,TCF12,SYT6,GRIA1,CCKBR,FBXL16,TJP1,TNFRSF1B,HPS5,TNS1,PCDH9,MAGI1,PDE1A,PDE1C,PDYN,GDAP1L1,CADM1,P2RY12,CNRIP1,POU3F2,PTPA,FEZ2,OSBPL3,ATRNL1,RAB39A,PRKCZ,IGSF1,CTNND1,MAPK10,SPIRE1,SYNC,PTHLH,PTPRD,NTM,KCNK2,KCNN3,DLG2,DLG3,TMEM255A,DNM2,C12orf4,RTN4,C2orf80" MicroRNA hsa-miR-1184:mirSVR_highEffct hsa-miR-1184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.58E-26 8.55E-23 1.02E-25 9.32E-25 63 925 "ADGRV1,EYA1,ARID1A,CSMD3,KLHL32,GRAMD1B,TOMM40L,SCN3A,FGF1,SEMA6C,FOLH1,DOCK10,NTNG1,NLGN1,MADD,ARHGAP5,CADPS,SORCS3,SMARCE1,RCOR3,ZSWIM8,NEK6,DNER,NPAS3,NELL1,PHLDB1,ARHGEF7,CASTOR3,PCDH11X,GNAS,DDHD2,NPPA,CACNB2,PTBP2,CAMK2G,VXN,VSTM2A,GRIA2,GRIA4,LINC00839,CRB1,LGI1,PRMT8,ST8SIA5,MFSD4A,CRLS1,SNCAIP,FEZ1,VCAN,CTNND1,DNAJC6,PLPPR1,JAKMIP2,KCNJ9,KCNMA1,KCNN3,SLC25A48,RALGDS,RFX4,RFX5,ZNF248,TTLL7,ABI2" MicroRNA hsa-miR-490-5p:mirSVR_highEffct hsa-miR-490-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-26 8.73E-23 1.04E-25 9.50E-25 56 720 "ACER3,ATAT1,WLS,SLC25A25,FGF14,ASRGL1,CDC42BPA,ANK2,PPFIA1,APBA2,NTNG1,SHTN1,CCDC88A,CADPS,PDE8B,SLCO1A2,GABBR1,CLASP2,ERBIN,ARHGEF7,CACNA1E,LRIT2,LILRA1,ZEB1,GRIA1,GRIA2,GRIN1,TF,TMEM257,HPS5,DCLK1,MAGI1,PDE3B,PRMT8,HMGB1,CA14,CASC2,NRXN1,PMP2,SLC25A27,BEST1,SPATA6,USP54,NRSN1,TOX,WBP1L,ZNF385B,HP1BP3,OCIAD1,PTPRD,DNAH9,RAB5B,RALGDS,DTNA,RGR,SLC4A10" MicroRNA hsa-miR-33b:mirSVR_highEffct hsa-miR-33b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.63E-26 8.82E-23 1.05E-25 9.59E-25 61 865 "EYA1,SLC25A25,CDC7,SCN3A,LINC00461,FGF14,UNC79,ERICH3,CDC42BPA,SH3GL2,SLITRK3,SORBS1,ZNF365,SLC1A6,MSR1,SLC14A1,SLCO1A2,SORCS3,DKK3,B3GALT2,ENKUR,SALL3,KIF1B,NAP1L2,NCAM1,COLGALT2,NDUFA5,ZNF638,KLHL4,ZEB1,PTBP2,GRIK2,GPR88,CRB1,AIFM1,LGI1,TPM3,PDE3B,LINC01102,GDAP1L1,CADM1,NRXN2,NOMO2,PPP3CB,RGS6,MICAL2,VCAN,MASP1,LRRTM3,PTHLH,PRDM2,KCNA4,PLPPR4,SLC17A6,GOPC,FAM13C,SLC6A15,RBM12,ARHGAP12,SLC4A10,EN2" MicroRNA hsa-miR-27a:PITA hsa-miR-27a:PITA_TOP PITA 1.64E-26 8.87E-23 1.05E-25 9.62E-25 54 665 "LGR4,EYA1,SLITRK1,KIAA1109,SEMA6A,TRIM46,ERICH3,ANK1,PPM1E,APBA2,MAGI3,GPAM,SLC1A2,PDE8B,RCOR3,SNAP25,ZCCHC24,CAB39,NEK6,NCAM1,COLGALT2,CAMTA1,CACNA1A,CACNB2,GRIA4,TMEM25,MFSD2A,CDC42,MAGI1,PDE3B,PRMT8,DLGAP3,CADM1,NRXN1,CABP1,POU3F2,PNKD,RGS6,EDRF1,WBP1L,CA10,KCNA6,SV2A,KCNK2,WIPF2,RET,JMJD1C,VANGL2,LPAR6,ARHGAP12,EN2,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-27b:PITA hsa-miR-27b:PITA_TOP PITA 1.64E-26 8.87E-23 1.05E-25 9.62E-25 54 665 "LGR4,EYA1,SLITRK1,KIAA1109,SEMA6A,TRIM46,ERICH3,ANK1,PPM1E,APBA2,MAGI3,GPAM,SLC1A2,PDE8B,RCOR3,SNAP25,ZCCHC24,CAB39,NEK6,NCAM1,COLGALT2,CAMTA1,CACNA1A,CACNB2,GRIA4,TMEM25,MFSD2A,CDC42,MAGI1,PDE3B,PRMT8,DLGAP3,CADM1,NRXN1,CABP1,POU3F2,PNKD,RGS6,EDRF1,WBP1L,CA10,KCNA6,SV2A,KCNK2,WIPF2,RET,JMJD1C,VANGL2,LPAR6,ARHGAP12,EN2,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-1273d:mirSVR_highEffct hsa-miR-1273d:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-26 9.31E-23 1.10E-25 1.01E-24 62 896 "ACER3,LDLRAD3,GALNT13,ADD3,AMER2,FCGR1A,SCN3A,LRRC7,FHL1,UNC79,USP28,GPAM,ARFGAP2,ASCL1,SORCS3,SON,MYT1L,TNIK,JPH4,NPAS3,GLS,ZNF638,NKX2-2,GNAS,DDHD2,CAMSAP2,TMEM136,ANO4,TCF7L2,VXN,GRID1,CDC42,PADI2,TPD52,MAGI1,PDE3B,MS4A7,NLGN3,ST8SIA5,VAV2,FAAP20,ACBD5,CRLS1,PPP2R5C,TENM4,ATRNL1,PLPP4,IGSF1,PRDM2,LRP8,OCIAD1,SMG7,KCNJ11,SLC17A6,DPP6,DTNA,ABCC9,INSYN2,ZNF248,VWA5A,CBLN2,EN2" MicroRNA hsa-miR-3156:mirSVR_highEffct hsa-miR-3156:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-26 9.48E-23 1.12E-25 1.03E-24 75 1318 "ACLY,SYT9,CSMD3,DSCAML1,FABP7,ERMN,ADORA3,SLC44A5,SCN3A,SOX6,ERICH3,CDC42BPA,SH3GL2,ZNF365,MIER1,SCMH1,NAXD,ASPH,TMEM108,NRG3,JPH4,KIF1B,NPAS3,NCAM1,ERBIN,DCAF5,AJAP1,ARHGEF7,GLS,KLHL4,GPM6A,ACSL6,DDR1,CACNB2,SYT6,GRIA4,TMEM25,TGFBR3,GUCY1A2,CDC42,SEZ6L,TPM4,MAGI1,PDE3B,ZMYND8,CASC2,TMEFF2,JAM2,NRXN1,FLRT1,SPATA6,POU3F2,RNF14,CRLS1,PPP3CB,FEZ2,OSBPL3,PRKCG,NRSN1,FGFR1OP2,SYNC,PLPPR1,CADM2,CEP170,MAGI2,KCNA6,RABGAP1L,SNX27,DLG2,DTNA,RTN4,PAK5,ABCC9,SLC6A15,RPRD1A" MicroRNA hsa-miR-942:mirSVR_highEffct hsa-miR-942:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-26 1.00E-22 1.18E-25 1.08E-24 89 1828 "ZFYVE27,LGR4,RTN3,ACTN2,ATAT1,MDM4,GALNT13,SLC44A5,GPR158,LRRTM4,FGF1,BCAR3,UNC79,MOG,SOX6,PPFIA1,APC,SLITRK3,ST3GAL3,LRRC4C,BCAS1,ZNF365,BCO1,ASCL1,ASPH,RCOR3,TNIK,IDI2-AS1,NCAM1,HEPN1,NEUROD1,SYT4,UNC5D,GOLGB1,ANO4,WSCD1,GPM6B,CACNA1E,LILRA1,PRLHR,TCF7L2,ZEB1,NUDT21,SYT6,NUMA1,GRIA2,GRIA4,GRIK2,SPX,PCDH9,MAGI1,PRMT8,ANO5,CHGA,ZFYVE9,NRXN1,A2ML1,DNAJC12,CELF5,SLC25A27,MFSD4A,PPP2R5C,SNCAIP,PRKACB,USP54,CTNND1,NRSN1,MAPK10,ANKS1B,PLPPR1,JAKMIP2,BDNF-AS,HP1BP3,LRP8,PTPRD,PTPRE,NTM,KCNK2,PCDH15,KCNMA1,NAV2,HS3ST4,PLEKHB2,DSCAM,FAM13C,VWA5A,FGFBP3,SLC4A10,YY1AP1" MicroRNA hsa-miR-34b:mirSVR_highEffct hsa-miR-34b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-26 1.05E-22 1.23E-25 1.13E-24 72 1218 "SDE2,EYA1,CSMD3,WAC,NLGN4X,GPR158,FGF14,FOXG1,ASRGL1,PPFIA1,APBA2,NTNG1,SLITRK3,ZCCHC17,NLGN1,ZNF365,SLC1A6,MSR1,ASPH,BRINP2,RCOR3,SNAP25,PALLD,DKK3,SON,SOX1,MYT1L,SOX5,SPART,LMO3,PCDH11X,ZNF638,DDHD2,ADGRL3,PTBP2,GRID1,OMG,ATG4C,MAEL,CDC42,C1orf94,LGI1,MAGI1,HNRNPK,PIK3CD,CCSER2,FAM181B,PRRX1,CNRIP1,SF1,VCAN,RBPJ,PRKACB,PKN2,FGFR1OP2,TOX,PTPRD,PTPRE,PCDH15,KCNMA1,CAB39L,KIF2A,DNAH9,SLC25A48,DTNA,BSDC1,SLC6A15,ZYG11B,FAM135B,RLBP1,RPRD1A,RCAN2" MicroRNA hsa-miR-624:mirSVR_highEffct hsa-miR-624:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.96E-26 1.06E-22 1.24E-25 1.14E-24 73 1252 "ADGRV1,KLHL32,SORCS1,TESK2,AGT,MOBP,FOXG1,ITSN1,PKP4,SORBS1,MIER1,RUFY2,MSR1,CCDC88A,PDE8B,FYN,PALLD,MEGF11,GABBR1,SON,MYT1L,ILDR2,SPART,PCDH11X,SYT4,CAMSAP2,ADGRL3,CACNA1A,GPM6A,TCF7L2,PTBP2,SYT6,VSTM2A,GRIA2,GRIA4,GRIK3,VWCE,CRB1,USP2,PCDH9,ARHGAP19,PCSK2,LINC01102,ZMYND8,NRXN1,PRRX1,PPP2R5C,PPP3CB,RGS6,PHACTR3,RBPJ,PRKACB,DOCK7,DZIP3,PUM1,KIAA0513,ANKS1B,LRRTM3,PMEPA1,CEP170,OLFM3,PTPRD,PCDH15,CAB39L,OLIG1,TMEM255A,RASGRF1,FAM13C,RTN4,PAK5,ZYG11B,JMJD1C,VWA5A" MicroRNA hsa-miR-147:mirSVR_highEffct hsa-miR-147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-26 1.07E-22 1.26E-25 1.16E-24 56 723 "RABEPK,ACER3,ACLY,SYT9,MRVI1,SLITRK1,TESK2,AMPH,ANK2,ANK3,PKP4,SYBU,MSR1,SLC8A3,SLN,SORCS3,ADGRA1,SCN3B,WDTC1,AHCYL1,JPH4,KIF1B,C11orf87,RND1,AJAP1,ZNF638,CAMTA1,KLHL4,PRUNE2,GRIA4,GPR88,MAEL,PCDH8,PDE1C,TMEFF2,BEST1,BTF3L4,SNCAIP,PPP3CB,FEZ1,ATRNL1,NRSN1,MASP1,CNIH3,CDH20,PTPRD,SV2A,FAM66C,DBX2,RTN4,L1CAM,RFX4,RFX5,FAM135B,RPRD1A,ELAVL4" MicroRNA hsa-miR-4251:mirSVR_highEffct hsa-miR-4251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.05E-26 1.11E-22 1.30E-25 1.19E-24 76 1356 "CDHR1,FABP7,SLC44A5,FCGR1A,GPR158,SCN3A,LRRC7,FGF14,SLC30A10,NTNG1,NLGN1,BCAS1,API5,MIER1,ARHGAP5,SLC8A2,SLC14A1,DACH2,RCOR3,FYN,NMNAT2,B4GALNT1,ADGRB2,NPAS3,ALDH1L1,ARHGEF7,GLS,ZNF638,CAMSAP2,GPM6A,CACNA1E,LRIT2,TCF7L2,ZEB1,TCF12,EML4,AKNA,GRIA4,RFFL,GRM3,TGFBR3,TMEM257,NEURL1,DCLK1,TPM4,PCSK2,MAGI1,BEST3,CA14,CASC2,TMEFF2,TLX1,NSD2,NXPH1,MED1,RBPJ,DOCK7,NRSN1,EDRF1,PLPPR5,LRRTM3,PLPPR1,HP1BP3,MAGI2,PTPRE,NTM,KCNJ10,DLG2,CAB39L,ZNF248,RLBP1,SYT15,SSPN,SIDT2,RPRD1A,EPB41L2" MicroRNA hsa-miR-629:mirSVR_lowEffct hsa-miR-629:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-26 1.14E-22 1.33E-25 1.22E-24 81 1534 "RABEPK,TTYH1,EPS8,MRVI1,CSMD2,WLS,RTKN,RTN1,KLRC4,SLITRK1,TMEM156,CHST15,SCN4B,LRRTM4,KIAA1109,SGIP1,ANK3,NTNG1,GPAM,PAAF1,AQP4,ARFGAP2,CCDC88A,CSPG5,PHYHIPL,WDTC1,SOX1,ZSWIM8,KIF1B,NDUFA5,ERBIN,NEUROD1,ACSBG1,GLS,CASTOR3,ASTN2,GNAS,CNTN2,KLHL4,SYT6,NUMA1,RFFL,CRB1,SEZ6L,LGI1,LINC01102,ANO5,MS4A7,NLGN3,NMT2,SULT4A1,PRRX1,NECAB2,SPATA6,ETNPPL,MICAL2,RAB39A,GON4L,PLPPR1,CADM2,CDH20,SV2A,KCNJ10,PCDH15,WIPF2,SLC17A6,ABI1,GOPC,FAM13C,RTN4,PAK5,BSDC1,FAM135B,ATL1,TTLL7,RNF220,RAVER2,ELAVL4,YY1AP1,OLIG2,TMEM100" MicroRNA hsa-miR-890:mirSVR_highEffct hsa-miR-890:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.14E-26 1.16E-22 1.35E-25 1.24E-24 68 1088 "ABAT,ZFYVE27,CSMD2,MDM4,F3,SORCS1,MOBP,MOG,APBA2,BCAS1,API5,SHTN1,MIER1,RUFY2,CCDC88A,ASPH,SMARCE1,SNAP25,PALLD,USP33,GAD2,AHCYL1,KIF1B,SPART,RGL1,GLS,LUZP2,DDHD2,GNG4,NODAL,TCF7L2,NRGN,PTBP2,NUDT21,EML4,GRIA2,GRIA4,USP2,TJP1,PCDH8,LGI1,PCSK2,HMGB1,ANO5,TMEFF2,NRXN1,BTF3L4,PRRX1,SPATA6,ACBD5,CNRIP1,PPP2R5C,PPP3CB,ATRNL1,PROX1,GON4L,CADM2,ELMO1,PRDM2,KCNC1,RAB5B,FAM66C,C12orf4,ABCC9,JMJD1C,ZNF248,FGFBP3,EPB41L2" MicroRNA hsa-miR-548b-3p:mirSVR_highEffct hsa-miR-548b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-26 1.22E-22 1.42E-25 1.31E-24 64 962 "WLS,F3,PLEKHG5,SLITRK1,WAC,FOXRED2,LRRTM4,LRRC7,SOX6,FOLH1,SH3GL2,APBA2,MAGI3,CACHD1,SYBU,ST3GAL3,SHTN1,PAAF1,ZNF365,RPH3A,MSR1,CSPG5,ASPH,BRINP2,SORCS3,RCOR3,ALDH4A1,SON,MYT1L,ENKUR,CPLX2,NPAS3,C11orf87,ZNF638,CAMSAP2,VXN,GRIA1,GRIA4,CCKBR,CRB1,INA,TMEM9,TNR,HMGB1,ANO5,A2ML1,FAM181B,FAT3,ACBD5,PPP2R5C,MICAL2,RBPJ,MASP1,LRRTM3,HP1BP3,KCNJ10,DLG2,PID1,TMEM255A,SLC6A15,RET,RFX4,SLC4A10,UEVLD" MicroRNA hsa-miR-210:mirSVR_lowEffct hsa-miR-210:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-26 1.25E-22 1.46E-25 1.34E-24 47 489 "MAPT,CEND1,MRVI1,CSMD2,ITSN1,SLITRK3,SORBS1,AQP4,NSG2,ASCL1,TMEM108,ADGRA1,MYT1L,LHFPL4,ADAM15,ALDH1L1,DCAF5,NEUROD1,MLC1,DCLK2,GNAS,CAMTA1,GPR17,NUDT21,GRIK2,CCKBR,PCDH8,ZMYND8,TMPRSS5,TLX1,NSD2,MFSD4A,POU3F2,TENM4,NOS1AP,DNAJC6,PTPRD,SUSD4,CRTAC1,RGS7,INSYN2,ATL1,ZNF248,SEC61A2,RPE65,EPB41L1,RCAN2" MicroRNA hsa-miR-3190-3p:mirSVR_highEffct hsa-miR-3190-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-26 1.26E-22 1.47E-25 1.35E-24 60 841 "RABEPK,SYT9,RTN3,KLHL32,FCGR1A,LRRTM4,MOBP,TRIM46,SGIP1,ZNF365,ASTN1,SMARCE1,TMEM108,ATM,MEGF11,MYT1L,TNIK,NEK6,GJB1,ARHGEF7,PCDH11X,DDHD2,ROBO3,CAMSAP2,PSRC1,PRUNE2,GPM6B,CACNB2,GRIA4,P2RX7,PAH,CDC42,LGI1,ZMYND8,BEST3,TMEFF2,HPCA,TJP2,ST8SIA5,C11orf49,BEST1,NSD2,TENM4,FEZ1,PRKCG,PLPP4,PKN2,PSMD13,PTHLH,CSDE1,DLG2,RAB5B,ATG16L1,GOPC,RTN4,FAM135B,PHC2,ELAVL4,PRRT4,EPB41" MicroRNA hsa-miR-622:mirSVR_highEffct hsa-miR-622:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-26 1.31E-22 1.52E-25 1.40E-24 58 783 "SDE2,PRR5L,LGR4,SYNDIG1,EYA1,MDM4,SORCS1,FCGR1B,TESK2,DISP3,FOXG1,MOG,AMPH,PPFIA1,NTNG1,SORBS1,API5,SHTN1,MIER1,PKNOX2,SLC14A1,NAXD,ZSWIM8,B4GALNT1,KIF1B,RCOR2,NELL1,ACSBG1,CAMTA1,KLHL4,ANO4,PTBP2,EML4,GRIA2,CYB561A3,CRB1,USP2,BTF3L4,PRRX1,ACBD5,MFSD4A,RGS6,RBPJ,MASP1,SPIRE1,ZNF385B,PSMD13,PCDH15,KCNN3,TMEM255A,SUSD4,DTNA,RTN4,RGS7,FAM135B,ZNF248,RNF220,SLC39A12" MicroRNA hsa-miR-1912:mirSVR_lowEffct hsa-miR-1912:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.66E-26 1.44E-22 1.68E-25 1.54E-24 86 1724 "SDE2,ZFYVE27,SYT9,RTN3,RCSD1,PAQR6,CSMD2,WLS,CSMD3,F3,KLHL32,FABP7,GRAMD1B,FCGR1A,FGF1,SEMA6A,SLC30A10,TRIM46,SEMA6C,GPAM,SLITRK3,BCAN,SORBS1,ZNF365,SFMBT2,SLC6A9,ARFGAP2,SLC8A2,MTR,SORCS3,ADGRA1,IGSF9B,ATP1A2,PALLD,GAD2,NMNAT2,LHFPL4,ADAM15,ALDH1L1,RCOR2,RGL1,KIRREL3,ROBO3,PSRC1,PRUNE2,DIRAS1,AZIN2,PTBP2,CECR2,CCKBR,LILRA4,MAGI1,PDE3B,CHGA,CAMKV,FADS2,BEST1,BTF3L4,COL9A2,CHD1L,PNKD,FEZ2,FEZ1,MICAL2,PLPP4,NRSN1,SYNC,PRDM2,OCIAD1,KCNA6,KCNC1,CCDC3,NAV2,PEX5,RAD52,FAM66C,ABCC9,RFX4,JMJD1C,ATL1,ZNF248,RPRD1A,EPB41,RCAN2,SEZ6,BAALC" MicroRNA hsa-miR-532-5p:mirSVR_highEffct hsa-miR-532-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-26 1.45E-22 1.68E-25 1.54E-24 66 1028 "KLHL32,SORCS1,TMEM156,LINC00461,ANK3,USP28,PPFIA1,CACHD1,SYBU,BCAS1,CCDC88A,RCOR3,PALLD,SON,TNIK,ENKUR,NPAS3,C11orf87,DCAF5,ARHGEF7,VAMP1,ZNF638,GNAS,CAMK2G,GRIA2,MFSD2A,TJP1,TLL2,ZFP91,PAH,CDC42,PCDH9,LGI1,HPSE2,CASC2,HNRNPK,NEGR1,ANLN,CCSER2,TJP2,SLC25A27,ACBD5,CHD1L,MED1,FEZ2,RBPJ,PRKACB,PKN2,CTNND2,NRSN1,GON4L,SPIRE1,HP1BP3,KCNA1,PLPPR4,PCDH15,RAD52,DPP6,C12orf4,DSCAM,PAK5,RFX4,RFX5,RAVER2,SLC4A10,RPE65" MicroRNA hsa-miR-520b:mirSVR_highEffct hsa-miR-520b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.35E-26 1.81E-22 2.10E-25 1.93E-24 75 1332 "EPS8,LGR4,MDM4,AMER2,GPR158,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,SLC14A1,RCOR3,MEGF11,MYT1L,TNIK,CAB39,ENKUR,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,SLCO1C1,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,GPM6A,ZEB1,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,HPS5,TNS1,C1orf94,PCDH9,LGI1,PCSK2,MAGI1,CASC2,PRRX1,SPATA6,ACBD5,CNRIP1,FEZ2,PRKACB,PKN2,IGSF1,MASP1,TOX,SYNC,PTHLH,CADM2,HP1BP3,RGMA,CSDE1,BLOC1S6,ZC3H11A,OLFM3,PTPRD,KCNMA1,HS3ST4,OLIG1,RAB5B,FAM13C,PAK5,ABCC9,SLC6A15,TMEM100" MicroRNA hsa-miR-516b:mirSVR_highEffct hsa-miR-516b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.49E-26 1.89E-22 2.19E-25 2.01E-24 67 1065 "ACER3,MBP,SYT9,ACTN2,DSCAML1,ADD3,TMEM156,ASIC4,BCAR3,BBOX1,AMPH,CDC42BPA,ITSN1,MAGI3,SORBS1,JAKMIP3,RUFY2,CCDC88A,CAPRIN2,MTR,ATM,SON,CAB39,ILDR2,JPH4,LMO3,COLGALT2,GFAP,ADGRL3,TMEM136,GPM6B,CACNB2,TCF7L2,CLEC9A,GRIA2,GRIA4,GRM3,OLR1,TMEM25,USP2,MAEL,PCDH9,LGI1,PRMT8,PDYN,FNDC5,TLX1,JAM2,NLGN3,SLC36A4,RGS6,MICAL2,OSBPL3,KIAA0408,PLPPR1,PTHLH,BLOC1S6,PTPRO,KCNN3,SLC6A15,ZYG11B,INSYN2,ARHGEF10L,SYT15,ARHGAP12,SLC4A10,PRRT4" MicroRNA hsa-miR-520e:mirSVR_highEffct hsa-miR-520e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.50E-26 1.90E-22 2.20E-25 2.01E-24 75 1333 "EPS8,LGR4,MDM4,WAC,AMER2,GPR158,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC1A6,YPEL4,SLC14A1,RCOR3,MYT1L,TNIK,ENKUR,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,GPM6A,ZEB1,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,HPS5,TNS1,C1orf94,PCDH9,PCSK2,MAGI1,CASC2,NRXN1,PRRX1,SPATA6,ACBD5,CNRIP1,SNCAIP,PPP3CB,FEZ2,PRKACB,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,PRTFDC1,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRD,KCNMA1,HS3ST4,SLC17A6,FAM13C,DTNA,PAK5,ABCC9,SLC6A15,TMEM100" MicroRNA hsa-miR-3160:mirSVR_highEffct hsa-miR-3160:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.71E-26 2.01E-22 2.32E-25 2.13E-24 62 909 "FABP7,FOXRED2,PLA2G6,LRRC7,BCAR3,ASRGL1,PPFIA1,NTNG1,MIER1,RPH3A,RUFY2,MSR1,CGREF1,PDE8B,SLIT1,CAPRIN2,PHYHIPL,ENKUR,IDI2-AS1,KIF1B,DNER,NELL1,ACSBG1,PCDH11X,GNG3,GNG4,NODAL,LRIT2,EML4,GRIK3,INA,ZFP91,MAEL,PCDH9,LGI1,TPM4,PCSK2,PDE3B,HERC2P3,HNRNPK,CADM1,ST8SIA5,PMP2,POU3F2,ETNPPL,CHD1L,MED1,PHACTR3,PRKAB2,PLPP4,PLD5,IGSF1,EDRF1,ANKS1B,CA10,PRDM2,LRP8,NTM,KCNK1,TMEM255A,DPP6,SLC6A15" MicroRNA hsa-let-7c:mirSVR_lowEffct hsa-let-7c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.82E-26 2.07E-22 2.39E-25 2.19E-24 88 1809 "RABEPK,ACER3,CDHR1,MEG3,GALNT13,SORCS1,TUBB4A,CHST15,TOMM40L,SNX32,SCN4B,ASIC4,CDC42BPA,ANK1,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,RUFY2,MSR1,SLC8A2,C10orf105,USP33,B3GALT2,ZSWIM8,ADAM15,NPAS3,NFASC,NDUFA5,NELL1,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,P2RX7,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,NTSR2,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,CELF5,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,BLOC1S6,PTPRD,KCNC1,RABGAP1L,TMCC2,DSCAM,RASGRF1,BSDC1,SLC6A15,NUP214,RBM12,ELAVL4,EPB41L2" MicroRNA hsa-miR-1271:mirSVR_highEffct hsa-miR-1271:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.97E-26 2.15E-22 2.48E-25 2.27E-24 59 820 "ABAT,KLHL32,ADD3,LRRC7,FHL1,SOX6,TRIM46,MAGI3,SYBU,SLC6A9,TAGLN3,BRINP2,FYN,SOX5,SOX10,GAD2,B4GALNT1,KIF1B,ADHFE1,AJAP1,ARHGEF7,GLS,PCDH11X,TBX15,GPM6A,GPM6B,CACNA1E,LILRA1,TCF7L2,ZEB1,PTBP2,GRIA1,GRID1,TF,CCKBR,LGI1,MAGI1,PDE1A,ANO5,PFKFB3,ANLN,OPALIN,PRRX1,MED1,CRLS1,CTNND1,ECE2,HP1BP3,PLPPR4,PTPRO,DSCAM,GNE,BSDC1,JMJD1C,FGFBP3,LPAR6,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-125a-3p:mirSVR_highEffct hsa-miR-125a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.99E-26 2.16E-22 2.49E-25 2.29E-24 68 1100 "RABEPK,ADGRV1,RTKN,ADD3,ADORA3,KIAA1109,BBOX1,MOBP,MAGI3,SLITRK3,NLGN1,RUFY2,NSG2,CADPS,SMARCE1,ATM,FYN,PALLD,ZSWIM8,B4GALNT1,EMC1,TTLL9,ADGRB2,NPAS3,LMO3,RGL1,GANAB,POPDC3,GNAS,GPM6A,DDR1,NPPA,ZEB1,CECR2,NUMA1,P2RX7,PCDH8,SEZ6L,LINC01102,HPSE2,JAM2,SEMA5B,A2ML1,CCSER2,MEAF6,BTF3L4,PRRX1,SNCAIP,RAB39A,IGSF1,KLK6,ANKS1B,PTCH1,ITGAV,CA10,CADM2,BLOC1S6,OCIAD1,PTPRE,PTPRZ1,NTM,PCDH15,KIF2A,SLC25A18,DTNA,ABCC9,SLC6A15,SLC4A10" MicroRNA hsa-miR-4276:mirSVR_lowEffct hsa-miR-4276:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.01E-26 2.17E-22 2.50E-25 2.29E-24 90 1887 "EPS8,PRR5L,WLS,MDM4,GRAMD1B,NLGN4X,SLC44A5,LRRTM4,KIAA1109,SOX6,SFPQ,SYBU,ST3GAL3,JAKMIP3,ZNF365,SPHKAP,ATM,PALLD,SON,WDTC1,SOX5,ARPP21,NEK6,TTLL9,GART,NAP1L2,SPART,C11orf87,NDUFA5,NHLH1,SEMA4A,UNC5D,ATF7,CACNB2,ZEB1,TCF12,TMEM151B,AKNA,GRIA4,GRIK2,OPCML,P2RX7,TMEM9,HPS5,CDH8,CASC2,SERPINE2,PIK3CD,UBTF,FADS2,ST8SIA5,SULT4A1,PTPA,RGS6,FEZ1,MICAL2,OSBPL3,PHACTR3,CTNND2,NRSN1,ECE2,WBP1L,ZNF385B,ITGAV,CA10,ZC3H11A,SRGAP3,KCNJ9,PCDH15,DLG2,NKAIN1,WIPF2,SLC25A48,C12orf4,DBX2,PAK5,ABCC9,ZYG11B,INSYN2,ATL1,ZNF248,VANGL2,SH3GLB1,RPRD1A,GPR61,ABI2,C2orf80,TMEM100,EPB41L1,UEVLD" MicroRNA hsa-miR-188-5p:mirSVR_lowEffct hsa-miR-188-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-26 2.23E-22 2.56E-25 2.35E-24 78 1442 "TTYH1,SDE2,RCSD1,ADGRV1,WAC,TMEM156,ADORA3,CHST15,SEMA6A,TRIM46,ASRGL1,SGIP1,ANXA7,GPAM,SORBS1,SHTN1,USP16,MSR1,PKNOX2,ARFGAP2,YPEL4,NSG2,SCG3,ARFGAP1,ATM,NRG3,SON,ILDR2,KIF1B,NFASC,NCAM1,LMO3,BCL2L2,GPR162,ERBIN,VAMP1,PCDH11X,CACNA1A,GPM6B,CACNB2,GPR19,TCF12,GRIA4,P2RX7,TLL2,REPS2,CDC42,RBFOX2,LGI1,TPM3,ZMYND8,BEST3,HMGB1,A2ML1,CCSER2,VAV2,SLC25A27,SLC36A4,NSD2,ACBD5,SF1,PPP3CB,MICAL2,VCAN,DZIP3,MASP1,ZBTB16,SYTL2,LRRTM3,PTCH1,KCNA1,FAM66C,RASGRF1,BSDC1,ZYG11B,JMJD1C,EPB41,EPB41L2" MicroRNA hsa-miR-30c-1*:mirSVR_highEffct hsa-miR-30c-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.23E-26 2.29E-22 2.63E-25 2.41E-24 70 1167 "MAG,RTN3,KCNIP2,NDRG2,SLITRK1,ADORA3,GPR158,SCN3A,KIAA1109,LRRC7,FHL1,MOBP,CDC42BPA,ITSN1,BCAN,NLGN1,SHTN1,PAAF1,MIER1,SLC8A3,SHANK2,SCMH1,SPHKAP,ASPH,GABBR1,ZSWIM8,AHCYL1,ADAM15,FXYD6,NASP,CLASP2,SLCO1C1,ARHGEF7,KLHL4,PRUNE2,CACNB2,VXN,SYT6,CYB561A3,CRB1,TMEM257,CDH10,LGI1,TPM3,PCSK2,CASC2,NLGN3,KIAA1549L,BTF3L4,CHD1L,PPP2R5C,RGS6,CTNND1,CTNND2,SPIRE1,LRRTM3,ZC3H11A,PTPRO,SV2A,AK5,KCNK2,RAB5B,DBX2,DTNA,RFX4,RNF220,SIDT2,GPR61,VWA5A,EPB41" MicroRNA hsa-miR-135a:PITA hsa-miR-135a:PITA_TOP PITA 4.71E-26 2.55E-22 2.92E-25 2.68E-24 45 449 "DPF1,EYA1,WAC,GPR158,ANK3,ANXA7,PPM1E,APC,NTNG1,GAS7,API5,PDE8B,SMARCE1,ATP2B2,MYT1L,ZCCHC24,AHCYL1,B4GALNT1,CPLX2,RGL1,ARHGEF7,CAMTA1,GNG3,NODAL,ANO4,PTBP2,PSD3,FBXL16,TMEM9,RBFOX2,FNDC5,NEGR1,PPP2R5C,ARHGEF4,NRSN1,NOS1AP,JAKMIP2,CEP170,STMN4,PTPRD,DLG2,RAB5B,PAK5,CAMK1G,EPB41" MicroRNA hsa-miR-135b:PITA hsa-miR-135b:PITA_TOP PITA 4.71E-26 2.55E-22 2.92E-25 2.68E-24 45 449 "DPF1,EYA1,WAC,GPR158,ANK3,ANXA7,PPM1E,APC,NTNG1,GAS7,API5,PDE8B,SMARCE1,ATP2B2,MYT1L,ZCCHC24,AHCYL1,B4GALNT1,CPLX2,RGL1,ARHGEF7,CAMTA1,GNG3,NODAL,ANO4,PTBP2,PSD3,FBXL16,TMEM9,RBFOX2,FNDC5,NEGR1,PPP2R5C,ARHGEF4,NRSN1,NOS1AP,JAKMIP2,CEP170,STMN4,PTPRD,DLG2,RAB5B,PAK5,CAMK1G,EPB41" MicroRNA hsa-miR-1322:mirSVR_highEffct hsa-miR-1322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.11E-26 2.77E-22 3.17E-25 2.91E-24 56 737 "CSMD3,NTNG1,MAGI3,MIER1,CCDC88A,SMARCE1,ATM,SON,B3GALT2,ARPP21,IDI2-AS1,KIF1B,LUZP2,DDHD2,CAMTA1,UNC5D,GPM6A,CACNA1E,NUDT21,VSTM2A,RFFL,GRIK2,TMEM25,CDC42,CDH8,LGI1,PDE1A,PDE1C,BEST3,TMEFF2,JAM2,ZFYVE9,FTO,CNTN1,PMP2,CHD1L,RBPJ,PKN2,NRSN1,TOX,PTHLH,CADM2,CNIH3,PRTFDC1,OLFM3,KCNK1,KCNK2,HS3ST4,TMEM255A,DTNA,RFX4,JMJD1C,ATL1,ZNF248,SLC4A10,C2orf80" MicroRNA hsa-miR-19a*:mirSVR_highEffct hsa-miR-19a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.57E-26 3.01E-22 3.44E-25 3.16E-24 73 1274 "SYT9,RTN3,CEND1,ADGRV1,ARID1A,RTN1,SORCS1,TOMM40L,SEMA6A,MOG,ANK3,USP28,SH3GL2,GPAM,API5,SHTN1,RCOR3,EIF4G3,PHYHIPL,PALLD,B3GALT2,SOX5,CAB39,GAD2,NAP1L2,RGL1,ZNF638,CAMTA1,ADGRL3,ZEB1,PTBP2,VSTM2A,GRIK2,PTPN5,P2RX7,CDH8,TPM4,PDE1C,CASC2,TUB,TMEFF2,JAM2,NRXN1,NEGR1,CCSER2,P2RY12,NSD2,MFSD4A,CP,POU3F2,KCNT2,FEZ2,MICAL2,PLCH2,CTNND1,MAPK10,ANKS1B,SPIRE1,PLPPR5,CA10,PRDM2,CEP170,CSDE1,PTPRD,AK5,KCNK2,TMEM255A,ABI1,DTNA,VWA5A,SLC4A10,ELAVL4,RPE65" MicroRNA hsa-miR-617:mirSVR_lowEffct hsa-miR-617:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.82E-26 3.15E-22 3.60E-25 3.30E-24 78 1450 "TTYH1,TMEM74,RTN3,PAQR6,LDLRAD3,SNX30,LINC00461,MOBP,SEMA6C,SLC1A7,DACH2,CAPRIN2,DKK3,SCN3B,SON,MYBPC1,WDTC1,NMNAT2,NEK6,DNER,NAP1L2,ZNF302,RGL1,AJAP1,VAMP1,RHBDL3,ZNF638,SYT4,SEMA4A,MYRF,UNC5D,ADGRL3,PRUNE2,TCF7L2,PTBP2,NUDT21,VXN,GRIA2,GRID1,FBXL16,CDC42,PADI2,PCDH8,CDH8,LGI1,TPM4,PDE4B,GPR37L1,CHRM1,SEMA5B,SLC36A4,PACSIN1,MED1,CRMP1,CRLS1,PPP2R5C,PPP3CB,NKAIN4,PKN2,FAM131B,WBP1L,PLPPR1,HP1BP3,LRP8,KCNH1,KCNJ9,KCNJ11,WIPF2,DNM2,DPP6,FAM13C,PAK5,NUP214,RET,RGR,RGS10,GPR61,SLC4A10" MicroRNA hsa-miR-216a:mirSVR_highEffct hsa-miR-216a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.92E-26 3.75E-22 4.27E-25 3.92E-24 76 1383 "SDE2,ADGRV1,ARID1A,CSMD3,F3,CDC7,SORCS1,LINC00461,FGF1,FGF14,SGIP1,GPAM,AQP4,ZNF365,SLC14A1,ASCL1,SCG3,SNAP25,NRG3,ZCCHC24,KIF21B,NEK6,NCAM1,DCAF5,GLS,ZNF638,DDHD2,UNC5D,ADGRL3,GOLGB1,ZEB1,GPR19,NRGN,EML4,VXN,GPR88,GRM3,OLR1,CRB1,ZFP91,MAGI1,PDE1C,BEST3,CADM1,ST8SIA5,NSD2,FAT3,CHD1L,VCAN,NCAN,CTNND1,CTNND2,TOX,ANKS1B,SYNC,LRRTM3,PMEPA1,PTHLH,CNIH3,MAGI2,KCNK2,PID1,TMEM255A,DPP6,SUSD4,DTNA,SLC6A15,RFX4,FAM135B,RPRD1A,ABI2,ARHGAP12,SLC4A10,EN2,OLIG2,RCAN2" MicroRNA hsa-let-7b:mirSVR_lowEffct hsa-let-7b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.79E-26 4.22E-22 4.80E-25 4.41E-24 91 1944 "RABEPK,CDHR1,MEG3,RTKN,GALNT13,SORCS1,TUBB4A,TOMM40L,SNX32,SCN4B,FGF1,ASIC4,HPCAL4,TRIM46,CDC42BPA,ANK1,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,MSR1,SLC8A2,C10orf105,USP33,B3GALT2,ZSWIM8,ADAM15,NPAS3,NFASC,NDUFA5,NELL1,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,NTSR2,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,CELF5,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,PRKACB,CMTM5,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,BLOC1S6,PTPRD,KCNC1,RABGAP1L,KCNJ10,TMCC2,ARNT2,DSCAM,RASGRF1,BSDC1,ABCC9,SLC6A15,NUP214,ELAVL4,EPB41L2,UEVLD" MicroRNA hsa-miR-1915*:mirSVR_lowEffct hsa-miR-1915*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.91E-26 4.28E-22 4.87E-25 4.47E-24 76 1386 "ABAT,SYT9,DUSP27,CSMD2,ADAR,TOMM40L,FGF1,SEMA6A,TRIM46,SGIP1,ITSN1,SORBS1,JAKMIP3,BCAS1,ZNF365,MIER1,SLCO1A2,DLL3,DDX25,ASTN1,PALLD,SOX1,ILDR2,JPH4,IDI2-AS1,BCL2L2,ALDH1L1,STOX1,ARHGEF7,OS9,KAZN,UNC5D,CLEC9A,CAMK2G,VXN,GRIN1,LINC00839,PTPN5,TMEM25,INA,AIFM1,RBFOX2,TPD52,ZMYND8,FNDC5,NRXN2,PMP2,BEST1,BTF3L4,MFSD4A,CP,CHD1L,SF1,TENM4,NKAIN4,RBPJ,PKN2,PRKCZ,CTNND2,ECE2,NOS1AP,PRDM2,PTPRD,SRGAP3,PEX5,WIPF2,RAB5B,SLC25A48,DNM2,DSCAM,CAMK1G,ZNF248,EEF1A2,SYT15,EFNA3,ELAVL4" MicroRNA hsa-miR-655-3p:TargetScan hsa-miR-655-3p TargetScan 8.14E-26 4.41E-22 5.01E-25 4.59E-24 51 606 "DPF1,RPL38,ACLY,RTN3,ADD3,ANK2,APC,GAS7,AQP4,ASCL1,CAPRIN2,B3GALT2,BCL2L2,GPR162,DCAF5,NFIA,PCDH11X,CAMTA1,CECR2,DDR2,GRIA1,GRM3,FBXL16,PAX6,CDC42,DCLK1,RBFOX2,PDE3B,HPSE2,HEPACAM,FEZ2,RBPJ,PROX1,DPYSL5,ANKS1B,JAKMIP2,PMEPA1,CADM2,MAGI2,RABGAP1L,RAB5B,GOPC,ABCC9,RFX4,RGS7,PIANP,RPRD1A,ABI2,EN2,EPB41,EPB41L2" MicroRNA hsa-miR-98:mirSVR_lowEffct hsa-miR-98:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.30E-26 4.50E-22 5.10E-25 4.68E-24 84 1678 "RABEPK,ACER3,CDHR1,MEG3,RTKN,CSMD3,GALNT13,SORCS1,TUBB4A,CHST15,TOMM40L,SCN4B,ASIC4,CDC42BPA,ANK1,PPFIA1,ITSN1,GPAM,SHTN1,MIER1,RPH3A,SLC1A7,RUFY2,MSR1,SLC8A2,C10orf105,B3GALT2,ZSWIM8,ADAM15,NPAS3,NDUFA5,STOX1,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,BTF3L4,ETNPPL,PNKD,RGS6,PRKACB,CMTM5,RAB39A,PKN2,KLK6,ZBTB16,ANKS1B,ZNF385B,PTAFR,LRP8,CSDE1,BLOC1S6,PTPRD,KCNC1,TMCC2,DSCAM,RASGRF1,BSDC1,ABCC9,SLC6A15,NUP214,RBM12,ELAVL4,EPB41L2,UEVLD" MicroRNA hsa-let-7e:mirSVR_lowEffct hsa-let-7e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.31E-26 4.50E-22 5.10E-25 4.68E-24 92 1985 "RABEPK,TTYH1,ACER3,CDHR1,RTKN,GALNT13,SORCS1,TUBB4A,CHST15,TOMM40L,SNX32,HOGA1,SCN4B,FGF1,ASIC4,TRIM46,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,RUFY2,MSR1,SLC8A2,C10orf105,USP33,B3GALT2,ADAM15,NPAS3,NFASC,NDUFA5,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,TPM3,LINC01102,GPR37L1,NTSR2,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,CELF5,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,CMTM5,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,MED24,BLOC1S6,PTPRD,KCNC1,PTPRO,TMCC2,NKAIN1,PARP11,DSCAM,RASGRF1,BSDC1,SLC6A15,NUP214,SIDT2,ELAVL4,EPB41L2,UEVLD" MicroRNA hsa-miR-1296:mirSVR_lowEffct hsa-miR-1296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.79E-26 4.76E-22 5.39E-25 4.95E-24 57 774 "MBP,MDM4,ERMN,KIAA1109,SOX6,ITSN1,DOCK10,SLC14A1,NAXD,ALDH4A1,FYN,SON,SOX10,TTLL9,NAP1L2,ZNF638,NHLH1,LUZP2,ATF7,DDR1,CACNB2,CAMK2G,CECR2,VXN,CCKBR,LINC00839,CRB1,MFSD2A,TJP1,NEURL1,CDC42,TPM3,PDE2A,PLEKHB1,CASC2,C11orf49,BTF3L4,IFFO1,CP,RGS6,ATRNL1,CMTM5,PROX1,LRRTM3,PTCH1,BDNF-AS,PTPRZ1,KCNJ11,PEX5,TMEM255A,DNM2,RALGDS,ATN1,RASGRF1,GNE,RGS7,ARHGEF10L" MicroRNA hsa-let-7a:mirSVR_lowEffct hsa-let-7a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.85E-26 4.79E-22 5.42E-25 4.97E-24 87 1793 "RABEPK,ACER3,CDHR1,RTKN,GALNT13,SORCS1,TUBB4A,CHST15,TOMM40L,SNX32,SCN4B,ASIC4,ANK1,ANK3,PPFIA1,ITSN1,GPAM,CACHD1,SHTN1,MIER1,SLC1A7,RUFY2,MSR1,SLC8A2,SLCO1A2,C10orf105,USP33,B3GALT2,ZSWIM8,ADAM15,NPAS3,NFASC,NDUFA5,STOX1,NELL1,MLC1,GOLGB1,ATF7,GPR26,PTBP2,SYT6,AKNA,GRIA2,GRIA4,GRIK2,GRIK3,TMEM25,FBXL16,DAAM2,MAEL,PAX6,TNFRSF1B,PCDH9,LINC01102,ANO5,PFKFB3,ASIC3,MS4A7,GDAP1L1,OPALIN,C11orf49,CELF5,BTF3L4,IFFO1,ETNPPL,PNKD,RGS6,RAB39A,PKN2,KLK6,ZBTB16,ZNF385B,PTAFR,CSDE1,BLOC1S6,PTPRD,KCNC1,RABGAP1L,TMCC2,DSCAM,RASGRF1,BSDC1,SLC6A15,NUP214,RBM12,ELAVL4,EPB41L2" MicroRNA hsa-miR-596:mirSVR_lowEffct hsa-miR-596:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.01E-26 4.88E-22 5.51E-25 5.06E-24 71 1216 "ZFYVE27,TMEM74,SYT9,LDLRAD3,RTKN,CLIP1,KLHL32,RXRG,AMER2,GPR158,TESK2,FGF1,GOLGA7B,SOX6,TRIM46,CNIH2,ITSN1,APBB1,DGKZ,PAAF1,MADD,LRRC55,CAPRIN2,ATP1A2,SON,SALL3,ADAM15,FXYD6,NFASC,BCL2L2,NDUFA5,NCDN,SEPT3,PCDH11X,DCLK2,GNAS,DDHD2,ATF7,CACNA1E,DDR1,GRID1,CYB561A3,CRB1,SPX,TGFBR3,MS4A7,SEMA5B,NEGR1,PIK3CD,UBTF,FADS2,ST8SIA5,MEAF6,BEST1,SNCAIP,OSBPL3,PHACTR3,ARHGEF4,ANKS1B,PLPPR5,CNIH3,PRDM2,SMG7,SV2A,KCNK2,PARP11,RALGDS,SLC25A41,DSCAM,NUP214,SYT15" MicroRNA hsa-miR-219-2-3p:mirSVR_highEffct hsa-miR-219-2-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.04E-26 4.90E-22 5.53E-25 5.07E-24 69 1149 "ABAT,ZFYVE27,ERMN,SNX32,SCN3A,KIAA1109,FGF1,LRRC7,AMPH,PPFIA1,GPAM,NLGN1,SHTN1,MSR1,SHANK2,ASPH,SLN,SNAP25,B3GALT2,IDI2-AS1,CLASP2,ALDH1L1,ARHGEF7,PCDH11X,CAMSAP2,TBX15,PRUNE2,GPM6A,PTBP2,CAMK2G,GRIA4,GRIK3,GRM3,OLR1,LINC00839,MAEL,HPS5,TPM4,MAGI1,LINC01102,HNRNPK,A2ML1,OPALIN,SPATA6,MFSD4A,FEZ2,RBPJ,PRKACB,FMN2,MAPK8,SYTL2,PLPPR1,PMEPA1,BDNF-AS,OLFM3,PCDH15,PEX5,DNAH9,GOPC,DSCAM,RASGRF1,SLC6A15,RET,RFX4,SEC61A2,RBM12,ABI2,SLC4A10,UEVLD" MicroRNA hsa-miR-3202:mirSVR_highEffct hsa-miR-3202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.44E-26 5.11E-22 5.76E-25 5.29E-24 67 1084 "CDHR1,ATAT1,RTKN,RXRG,NLGN4X,TESK2,FHL1,PPFIA1,SH3GL2,NTNG1,GPAM,ZNF365,MIER1,RPH3A,CCDC88A,GABBR1,SON,JPH4,LMO3,COLGALT2,NDUFA5,STOX1,VAMP1,PCDH11X,GNAS,CNDP1,TCF12,NRGN,CECR2,TMEM151B,GRIK2,TF,OLR1,CCKBR,ZFP91,CDC42,TNR,TPM3,ZMYND8,BEST3,CHGA,PLEKHB1,GDAP1L1,CADM1,NRXN2,PMP2,BEST1,CP,POU3F4,SF1,CRMP1,KLK6,PHYHIP,HP1BP3,OLFM3,PTPRD,SMG7,SV2A,PCDH15,SNX27,HS3ST4,DNAH9,RAB5B,VANGL2,RNF220,EFNA3,FGFBP3" MicroRNA hsa-miR-337-3p:mirSVR_highEffct hsa-miR-337-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-25 5.44E-22 6.13E-25 5.62E-24 68 1118 "RABEPK,ACER3,LDLRAD3,SLITRK1,CDC7,SORCS1,HOGA1,LRRC7,SFPQ,ERICH3,SH3GL2,NTNG1,GPAM,SLITRK3,API5,SLC1A7,CCDC88A,MTR,SORCS3,SMARCE1,DKK3,KIF21B,ARPP21,NCAM1,LMO3,ZNF302,SYT4,GOLGB1,GPM6A,DDR1,PTBP2,VXN,GRIA4,GRIK2,GPR88,CRB1,LEFTY2,TJP1,ZDHHC22,PCDH9,PDE3B,CNTN1,ACBD5,CHD1L,MED1,SNCAIP,ATRNL1,RBPJ,PRKAB2,RAB39A,CTNND2,PUM1,FGFR1OP2,GON4L,SPIRE1,PTCH1,CNIH3,HP1BP3,OCIAD1,KLRC2,PID1,SLC17A6,ABI1,GOPC,SLC6A15,INSYN2,SSPN,BAALC" MicroRNA hsa-miR-4275:mirSVR_highEffct hsa-miR-4275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-25 5.65E-22 6.35E-25 5.83E-24 63 958 "ACER3,ACTN2,CSMD3,ADAR,KLHL32,WAC,TESK2,LRRTM4,KIAA1109,FGF1,MOG,PPFIA1,MAGI3,SYBU,JAKMIP3,MIER1,SLC1A7,MSR1,ARHGAP5,RCOR3,ATM,CAB39,NAP1L2,BCL2L2,NDUFA5,SEPT3,ZNF638,SYT4,GNAS,DDHD2,CAMTA1,GRIA4,CDC42,ARHGAP19,PDE1C,PDE3B,HMGB1,CCSER2,SLC25A27,SPATA6,PPP3CB,RBPJ,IGSF1,MASP1,TOX,ITGAV,CSDE1,MAGI2,BLOC1S6,OLFM3,KCNA4,OCIAD1,SMG7,PTPRZ1,NTM,CCDC3,PCDH15,C12orf4,GNE,SLC6A15,RET,JMJD1C,RAVER2" MicroRNA hsa-miR-27a*:mirSVR_lowEffct hsa-miR-27a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-25 5.97E-22 6.71E-25 6.15E-24 67 1087 "ABAT,SYT9,MEG3,CSMD2,RTKN,ADCY2,ADD3,FABP7,CHST15,HOGA1,DISP3,BBOX1,ELMOD1,TRIM46,SFPQ,ANK3,PKP4,GPAM,NBPF1,LRRC55,MT3,NSG2,CGREF1,BRINP2,USP33,WDTC1,GAD2,SALL3,ADGRB2,BCL2L2,RGL1,PHLDB1,VAMP1,ROBO3,UNC5D,ZEB1,SPX,USP2,TIE1,NEURL1,PAH,PRMT8,ZMYND8,ASIC3,CASC2,NEGR1,OPALIN,CNTN1,MEAF6,BEST1,RNF14,PPP3CB,RGS6,WBP1L,GON4L,SPIRE1,ZNF385B,CA10,BDNF-AS,PTHLH,RGMA,KCNJ9,KCNMA1,PYGM,WIPF2,RALGDS,RTN4" MicroRNA hsa-miR-744*:mirSVR_lowEffct hsa-miR-744*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-25 6.04E-22 6.78E-25 6.22E-24 82 1611 "SYNDIG1,MEG3,CSMD2,CSMD3,GALNT13,ADORA1,TOMM40L,LINC00461,MOG,PDZD4,ANK3,ITSN1,PKP4,DGKZ,ZNF365,KIAA1614,SLC1A6,MSRA,ARFGAP2,MTR,SMARCE1,SNAP25,ATP1A2,PHYHIPL,SOX5,GAD2,AHCYL1,BCL2L2,FAM168A,ARHGEF7,CASTOR3,CNTN2,PRLHR,AZIN2,PSD3,GRIA2,CYB561A3,GRM3,OPCML,TMEM25,TGFBR3,HPS5,PCDH9,LGI1,TPM3,PCSK2,PDE3B,MS4A7,TJP2,NSD2,FAT3,BTBD17,SNCAIP,MICAL2,PHACTR3,PRKAB2,PUM1,WBP1L,SYTL2,ANKS1B,GON4L,SPIRE1,PTAFR,DNAJC6,PTHLH,CDH20,OCIAD1,PTPRD,PTPRO,SV2A,NTM,KCNK1,DLG2,DNAH9,SLC17A6,ATN1,FAM13C,ABCC9,RFX4,ZNF248,RBM12,EPB41" MicroRNA hsa-miR-92a-1*:mirSVR_lowEffct hsa-miR-92a-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-25 6.23E-22 6.98E-25 6.40E-24 77 1430 "ACHE,CEND1,ECSIT,MDM4,DSCAML1,SORCS1,GRAMD1B,ADORA3,TOMM40L,SNX32,MOBP,MOG,ANK1,CNIH2,ITSN1,APBB1,SFMBT2,SLC8A2,NSG2,CAPRIN2,SLN,B3GAT1,ATP2B2,B3GALT2,ZSWIM8,NMNAT2,KIF1B,KIRREL3,SEPT3,RHBDL3,MYRF,MMD2,KLHL4,WSCD1,ZEB1,GPR17,NRGN,HAP1,PTBP2,PCDHGA3,TMEM151B,RFFL,OLR1,TGFBR3,USP2,FBXL16,TMEM9,ZDHHC22,ZFP91,HPS5,CDH8,ZNF384,PDE2A,ANO5,CHRNB2,NRXN2,SULT4A1,CNTN1,SLC25A27,NECAB2,ACBD5,MICAL2,PLCH2,IGSF1,KLK6,ACY3,ANKS1B,KCNC1,SV2A,SNX27,DLG3,WIPF2,FAM66C,PAK5,ARHGEF10L,PHC2,ABI2" MicroRNA hsa-miR-1276:mirSVR_highEffct hsa-miR-1276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-25 6.28E-22 7.03E-25 6.45E-24 69 1154 "SDE2,ABAT,TMEM74,ATAT1,LDLRAD3,CLIP1,LRRTM4,LRRC7,SEMA6A,FHL1,MOBP,SELL,AMPH,ERICH3,RASA3,USP28,ITSN1,APC,MAGI3,GPAM,SORBS1,SYBU,MIER1,SLIT1,SMARCE1,PHYHIPL,SON,MYBPC1,DNER,NCAM1,LMO3,KIRREL3,ARHGEF7,GLS,DCLK2,UNC5D,PRUNE2,GPM6B,GRIA1,GRID1,ZFP91,MAGI1,PDYN,HNRNPK,SERPINE2,ST8SIA5,NXPH1,CNRIP1,PPP2R5C,MICAL2,ATRNL1,VCAN,PHACTR3,PRKACB,CTNND2,SYTL2,TOMM20,PLPPR5,ITGAV,PLPPR1,CADM2,LRP8,PTPRD,SMG7,KCNK2,WIPF2,DTNA,VANGL2,RNF220" MicroRNA hsa-miR-454-3p:TargetScan hsa-miR-454-3p TargetScan 1.17E-25 6.36E-22 7.08E-25 6.50E-24 55 721 "PRR5L,MDM4,NDRG2,F3,ADARB2,CLIP1,RTN1,ADCY2,GPR158,MIER1,CCDC88A,CAPRIN2,FYN,ATP2B2,MYT1L,SALL3,NEUROD1,AJAP1,NFIA,CAMSAP2,PRUNE2,PTBP2,GRIK2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,PRKACB,ARHGEF4,PROX1,PSD,PMEPA1,CADM2,LRP8,CEP170,KCNA4,CDH20,PTPRD,KCNJ10,NAV2,KCNN3,DLG2,RAB5B,DNM2,ATG16L1,RPRD1A,ARHGAP12,EPB41L1" MicroRNA hsa-miR-130b-3p:TargetScan hsa-miR-130b-3p TargetScan 1.17E-25 6.36E-22 7.08E-25 6.50E-24 55 721 "PRR5L,MDM4,NDRG2,F3,ADARB2,CLIP1,RTN1,ADCY2,GPR158,MIER1,CCDC88A,CAPRIN2,FYN,ATP2B2,MYT1L,SALL3,NEUROD1,AJAP1,NFIA,CAMSAP2,PRUNE2,PTBP2,GRIK2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,PRKACB,ARHGEF4,PROX1,PSD,PMEPA1,CADM2,LRP8,CEP170,KCNA4,CDH20,PTPRD,KCNJ10,NAV2,KCNN3,DLG2,RAB5B,DNM2,ATG16L1,RPRD1A,ARHGAP12,EPB41L1" MicroRNA hsa-miR-130a-3p:TargetScan hsa-miR-130a-3p TargetScan 1.17E-25 6.36E-22 7.08E-25 6.50E-24 55 721 "PRR5L,MDM4,NDRG2,F3,ADARB2,CLIP1,RTN1,ADCY2,GPR158,MIER1,CCDC88A,CAPRIN2,FYN,ATP2B2,MYT1L,SALL3,NEUROD1,AJAP1,NFIA,CAMSAP2,PRUNE2,PTBP2,GRIK2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,PRKACB,ARHGEF4,PROX1,PSD,PMEPA1,CADM2,LRP8,CEP170,KCNA4,CDH20,PTPRD,KCNJ10,NAV2,KCNN3,DLG2,RAB5B,DNM2,ATG16L1,RPRD1A,ARHGAP12,EPB41L1" MicroRNA hsa-miR-301a-3p:TargetScan hsa-miR-301a-3p TargetScan 1.17E-25 6.36E-22 7.08E-25 6.50E-24 55 721 "PRR5L,MDM4,NDRG2,F3,ADARB2,CLIP1,RTN1,ADCY2,GPR158,MIER1,CCDC88A,CAPRIN2,FYN,ATP2B2,MYT1L,SALL3,NEUROD1,AJAP1,NFIA,CAMSAP2,PRUNE2,PTBP2,GRIK2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,PRKACB,ARHGEF4,PROX1,PSD,PMEPA1,CADM2,LRP8,CEP170,KCNA4,CDH20,PTPRD,KCNJ10,NAV2,KCNN3,DLG2,RAB5B,DNM2,ATG16L1,RPRD1A,ARHGAP12,EPB41L1" MicroRNA hsa-miR-301b-3p:TargetScan hsa-miR-301b-3p TargetScan 1.17E-25 6.36E-22 7.08E-25 6.50E-24 55 721 "PRR5L,MDM4,NDRG2,F3,ADARB2,CLIP1,RTN1,ADCY2,GPR158,MIER1,CCDC88A,CAPRIN2,FYN,ATP2B2,MYT1L,SALL3,NEUROD1,AJAP1,NFIA,CAMSAP2,PRUNE2,PTBP2,GRIK2,KCNK10,PAX6,RBFOX2,PDE3B,PFKFB3,CCSER2,BTF3L4,FAT3,ACBD5,POU3F2,CHD5,PRKACB,ARHGEF4,PROX1,PSD,PMEPA1,CADM2,LRP8,CEP170,KCNA4,CDH20,PTPRD,KCNJ10,NAV2,KCNN3,DLG2,RAB5B,DNM2,ATG16L1,RPRD1A,ARHGAP12,EPB41L1" MicroRNA hsa-miR-1208:mirSVR_highEffct hsa-miR-1208:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-25 7.96E-22 8.86E-25 8.13E-24 66 1060 "CNTNAP3,ADGRV1,LDLRAD3,CSMD3,ADAR,ADCY2,SLITRK1,ADD3,SORCS1,SLC44A5,FHL1,TRIM46,ANK3,DGKZ,SHTN1,MIER1,RUFY2,SLC8A3,CCDC88A,DACH2,CAPRIN2,ASTN1,RCOR3,SNAP25,CCDC181,SON,MYT1L,RGL1,GLS,VAMP1,CAMSAP2,ADGRL3,GPM6B,ZEB1,GRIA4,GRIK4,TLL2,PTGDR2,CASC2,ANLN,FLRT1,FAM181B,BTF3L4,FAAP20,CP,PPP2R5C,ATRNL1,USP54,NRSN1,ANKS1B,ZNF385B,PTCH1,PTHLH,CADM2,DPP6,ABI1,FAM13C,DTNA,SLC6A15,USH1C,RFX4,TTLL7,RBM12,FGFBP3,EPB41L1,BAALC" MicroRNA hsa-miR-10a:mirSVR_lowEffct hsa-miR-10a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-25 8.58E-22 9.53E-25 8.74E-24 80 1546 "RABEPK,ZFYVE27,MBP,CSMD2,SORCS1,GRAMD1B,FOXRED2,NLGN4X,LRRTM4,DISP3,SEMA6A,ANK1,ANK3,SFMBT2,URGCP,MSR1,LRRC55,SLC8A3,CGREF1,BRINP2,MYT1L,LHFPL4,KIF1B,SPART,ALDH1L1,ERBIN,RGL1,SEPT3,GNAS,DDHD2,UNC5D,ATF7,ACSL6,NEU4,AZIN2,CAMK2G,AKNA,GRIK3,GRIK4,GRM3,TGFBR3,ZDHHC22,DAAM2,PRMT8,GPR37L1,HNRNPK,NEGR1,PIK3CD,NMT2,A2ML1,OPALIN,TJP2,FTO,PLXNB3,ATCAY,MED1,FEZ1,NRSN1,EDRF1,PSD,GON4L,SPIRE1,BDNF-AS,ITIH2,CSDE1,PTPRO,SRGAP3,PCDH15,FAM57B,GOPC,GNE,FAM135B,INSYN2,ZNF248,SSPN,RBM12,GPR61,FGFBP3,RAVER2,UEVLD" MicroRNA hsa-miR-3138:mirSVR_highEffct hsa-miR-3138:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-25 9.47E-22 1.05E-24 9.64E-24 61 905 "ARID1A,TOMM40L,SNX32,KIAA1109,SEMA6A,ASIC4,MOBP,TRIM46,SH3GL2,PPM1E,ZNF365,CGREF1,SORCS3,PALLD,GAD2,LMO3,CLASP2,NDUFA5,SLCO1C1,PCDH11X,POPDC3,DCLK2,DDR1,PCDHGA3,CECR2,CYB561A3,CRB1,GUCY1A2,TIE1,CDC42,CDH8,PDE3B,CIART,FNDC5,CHRM1,CASC2,HERC2P3,ZFYVE9,NRXN2,BEST1,RNF14,RGS6,FEZ1,PKN2,USP54,MAPK10,EDRF1,MASP1,SYTL2,PTHLH,KCNA2,KCNK1,CAB39L,TMEM255A,DTNA,PAK5,RGR,FAM135B,ZNF248,RBM12,EPB41" MicroRNA hsa-miR-141*:mirSVR_highEffct hsa-miR-141*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.04E-25 1.10E-21 1.22E-24 1.12E-23 73 1302 "ACER3,MRVI1,WLS,ADD3,SORCS1,AMER2,CHST15,KIAA1109,MOBP,MOG,AMPH,ERICH3,PPFIA1,NTNG1,SHTN1,PAAF1,MADD,MSR1,SPHKAP,RCOR3,PALLD,SON,ILDR2,ERBIN,AJAP1,SLCO1C1,ARHGEF7,PCDH11X,ZNF638,LUZP2,DDHD2,CAMSAP2,UNC5D,ANO4,PTBP2,NUDT21,GRIA4,CRB1,FBXL16,TMEM9,AIFM1,CDC42,PRMT8,CIART,PDYN,HMGB1,JAM2,ZFYVE9,NRXN1,MEAF6,BTF3L4,SLC36A4,NSD2,CP,CHD1L,CRMP1,KCNT2,PRKAB2,PRKCG,MASP1,KLK6,ACY3,ZNF385B,SIRPA,PRDM2,KCNK2,DLG2,TMEM255A,FAM13C,TTLL7,RPRD1A,SLC4A10,BAALC" MicroRNA hsa-miR-424*:mirSVR_lowEffct hsa-miR-424*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.15E-25 1.16E-21 1.29E-24 1.18E-23 63 971 "PAQR6,MRVI1,CSMD3,CLIP1,WAC,SORCS1,SLC44A5,CHST15,FHL1,SELL,PPFIA1,SYBU,NLGN1,PKNOX2,SLC8A3,DACH2,ASPH,DNER,ALDH1L1,SMOC1,GANAB,MLC1,GNG4,UNC5D,PRLHR,TCF7L2,TCF12,CAMK2A,CECR2,BRSK2,GRIA4,TJP1,ZFP91,CDC42,CDH10,MAGI1,BEST3,NEGR1,BTF3L4,CHD1L,MED1,CRLS1,PPP2R5C,PPP3CB,PLD5,TOMM20,ZNF385B,CA10,PLPPR1,PRTFDC1,PLPPR4,KCNK2,PCDH15,PID1,C12orf4,SUSD4,SLC6A15,ZYG11B,ZNF248,SSPN,SLC4A10,TMEM100,EPB41" MicroRNA hsa-miR-1297:mirSVR_lowEffct hsa-miR-1297:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-25 1.24E-21 1.37E-24 1.26E-23 86 1780 "SDE2,PRR5L,ACER3,ARID1A,KLHL32,ERMN,NLGN4X,SLC44A5,FCGR1B,LRRC7,MOBP,SELL,AMPH,ASRGL1,PPFIA1,ITSN1,PKP4,NTNG1,MAGI3,GPAM,SLITRK3,ST3GAL3,MSRA,LRRC55,SHANK2,ASPH,SMARCE1,ATM,PHYHIPL,KIF21B,ADHFE1,NEUROD1,SEPT3,PCDH11X,DDHD2,ANO4,GPM6B,PRLHR,TCF7L2,TCF12,NUDT21,CECR2,PSD3,GRIA2,GRIK2,OPCML,TMEM25,GUCY1A1,KCNK10,C1orf94,SEZ6L,TPD52,PDE4B,PDYN,SCRG1,CHRNB2,HNRNPK,TMEFF2,GDAP1L1,PIK3CD,A2ML1,VAV2,NSD2,CP,KCNT2,ATRNL1,PRKACB,DOCK7,PUM1,EDRF1,KIAA0408,TOX,ZNF385B,PTCH1,BDNF-AS,OCIAD1,PTPRE,KCNH1,RABGAP1L,CAB39L,PID1,SLC17A6,ATG16L1,SSPN,RPE65,SEZ6" MicroRNA hsa-miR-3074:mirSVR_lowEffct hsa-miR-3074:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.39E-25 1.29E-21 1.43E-24 1.31E-23 89 1897 "RABEPK,LGR4,RCSD1,EYA1,ADCY2,SORCS1,SNX30,FOXRED2,LRRTM4,KIAA1109,SOX6,FOXM1,ERICH3,ITSN1,PKP4,SESN3,APC,CCDC80,NLGN1,CCDC88A,SLC14A1,SLCO1A2,SLIT1,SORCS3,SNAP25,SCN3B,USP33,CAB39,DNER,C11orf87,NDUFA5,RGL1,ADHFE1,NEUROD1,SLCO1C1,NFIA,GLS,PCDH11X,ADGRL3,ANO4,CACNB2,VXN,VSTM2A,GRID1,GRIN1,GPR88,OMG,CRB1,TLL2,CDC42,PCDH9,PDE3B,BEST3,HMGB1,CASC2,NLGN3,CADM1,CNTN1,NSD2,FAAP20,CNRIP1,CRLS1,SNCAIP,KCNT2,OSBPL3,PRKCZ,NRSN1,KIAA0408,TOX,PLPPR5,PLPPR1,HP1BP3,MAGI2,ZC3H11A,KCNA1,PLPPR4,PTPRZ1,SRGAP3,KCNK2,KLRC2,FAM13C,RTN4,ABCC9,ZYG11B,RFX5,ABI2,SLC4A10,EPB41,EPB41L2" MicroRNA hsa-miR-124*:mirSVR_highEffct hsa-miR-124*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-25 1.31E-21 1.45E-24 1.33E-23 64 1005 "IL17D,CDC7,AMER2,FOXG1,PPFIA1,APC,MAGI3,GPAM,SORBS1,MIER1,RUFY2,MSR1,SHANK2,DACH2,ASPH,MTR,SMARCE1,SNAP25,MEGF11,KIF21B,JPH4,TTLL9,IDI2-AS1,NCAM1,KIRREL3,ADHFE1,ARHGEF7,SEMA4A,ADGRL3,GPM6A,CACNA1E,DDR1,ZEB1,TCF12,PTBP2,TMEM257,PCDH9,DCLK1,PDE3B,PDE4B,CHGA,CASC2,HNRNPK,OPALIN,SLC25A27,BEST1,PPP3CB,MICAL2,OSBPL3,RBPJ,PRKCZ,PLPPR5,TUBB2B,ZNF385B,CAB39L,PID1,TMEM255A,SLC25A48,DTNA,BSDC1,ABCC9,USH1C,RNF220,EPB41L2" MicroRNA hsa-miR-376b:mirSVR_highEffct hsa-miR-376b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.58E-25 1.40E-21 1.54E-24 1.41E-23 70 1204 "RABEPK,MDM4,DSCAML1,SLC30A10,ANK2,DOCK10,APC,CCDC88A,ASPH,SORCS3,RCOR3,PHYHIPL,MEGF11,IDI2-AS1,ADGRB2,SPART,DCAF5,SYT4,PSRC1,VXN,SYT6,GRIA4,GRIK2,INA,TJP1,CDC42,RBFOX2,TPD52,PDE3B,PRMT8,PDE4B,ZMYND8,TMEFF2,NRXN1,CCSER2,PMP2,BTF3L4,SPATA6,MFSD4A,CP,MED1,PPP3CB,KCNT2,ATRNL1,PRKACB,PKN2,EDRF1,MASP1,ANKS1B,PSMD13,PTHLH,COPS7A,CSDE1,OLFM3,OCIAD1,DNAH9,RAB5B,SLC17A6,PARP11,DPP6,PAK5,ABCC9,SLC6A15,ZYG11B,RFX4,JMJD1C,FAM135B,SIDT2,TMEM100,EPB41" MicroRNA hsa-miR-670:mirSVR_lowEffct hsa-miR-670:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-25 1.40E-21 1.54E-24 1.41E-23 85 1745 "SERPINA3,ACER3,MAP6,SYT9,ATAT1,LDLRAD3,CSMD2,RTKN,WAC,SORCS1,SNX32,SCN4B,ASIC4,MOBP,FOXM1,ANK3,PPFIA1,ITSN1,GPAM,DGKD,BCAN,JAKMIP3,RPH3A,SFMBT2,PKNOX2,YPEL4,NSG2,SLC14A1,CGREF1,SORCS3,DKK3,WDTC1,KIF21B,AHCYL1,ADGRB2,BCL2L2,RGL1,DCLK2,ROBO3,MYRF,UNC5D,MMD2,BRSK2,USP2,GUCY1A1,AIFM1,TNFRSF1B,LGI1,TPD52,TPM3,PDE3B,HPSE2,DUSP26,NRXN1,PIK3CD,CPT1C,A2ML1,NSD2,POU3F2,MED1,PTPA,MICAL2,EDRF1,MASP1,ZBTB16,PTCH1,COPS7A,PTPRO,KCNJ10,DLG2,RAB5B,KLRC2,FAM66C,RAP1GAP,RTN4,BSDC1,SLC6A15,NUP214,RET,RFX4,SH3GLB1,GPR61,ABI2,ELAVL4,RPE65" MicroRNA hsa-miR-2115:mirSVR_highEffct hsa-miR-2115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-25 1.45E-21 1.59E-24 1.46E-23 63 975 "ACER3,ACLY,CSMD2,MDM4,WAC,TOMM40L,SNX32,FHL1,PPFIA1,ITSN1,PKP4,APC,ST3GAL3,SHTN1,PAAF1,SLC8A3,RCOR3,ATP2B2,PALLD,SON,SOX5,AHCYL1,ENKUR,JPH4,TTLL9,NPAS3,NASP,NCAM1,ERBIN,ADHFE1,PCDH11X,ZNF638,CAMTA1,CACNB2,TCF7L2,VSTM2A,GRIA4,ZFP91,PCDH8,PDE1A,PDE2A,PRMT8,ZMYND8,NRXN1,ST8SIA5,CCDC136,MEAF6,BTF3L4,CP,CHD1L,SNCAIP,PPP3CB,USP54,NRSN1,CADM2,CEP170,CSDE1,KCNA2,PCDH15,FAM13C,SEC61A2,CBLN2,ROM1" MicroRNA "TGTTTAC,MIR-30A-5P:MSigDB" "TGTTTAC,MIR-30A-5P:MSigDB" MSigDB 2.69E-25 1.46E-21 1.59E-24 1.46E-23 48 543 "MAP6,SCN3A,SEMA6A,FOXG1,ITSN1,DGKZ,NLGN1,SLC1A2,SLC6A9,CADPS,SPHKAP,SORCS3,ATP2B2,SON,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,GRIA2,GRM3,OMG,TLL2,CELF3,LGI1,PIK3CD,MICAL1,DOCK7,CTNND2,FAM131B,KIAA0408,WBP1L,CA10,MAGI2,PLPPR4,SRGAP3,PAK5,TTLL7,RNF220,EFNA3,ELAVL3,EPB41" MicroRNA "TGTTTAC,MIR-30B:MSigDB" "TGTTTAC,MIR-30B:MSigDB" MSigDB 2.69E-25 1.46E-21 1.59E-24 1.46E-23 48 543 "MAP6,SCN3A,SEMA6A,FOXG1,ITSN1,DGKZ,NLGN1,SLC1A2,SLC6A9,CADPS,SPHKAP,SORCS3,ATP2B2,SON,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,GRIA2,GRM3,OMG,TLL2,CELF3,LGI1,PIK3CD,MICAL1,DOCK7,CTNND2,FAM131B,KIAA0408,WBP1L,CA10,MAGI2,PLPPR4,SRGAP3,PAK5,TTLL7,RNF220,EFNA3,ELAVL3,EPB41" MicroRNA "TGTTTAC,MIR-30C:MSigDB" "TGTTTAC,MIR-30C:MSigDB" MSigDB 2.69E-25 1.46E-21 1.59E-24 1.46E-23 48 543 "MAP6,SCN3A,SEMA6A,FOXG1,ITSN1,DGKZ,NLGN1,SLC1A2,SLC6A9,CADPS,SPHKAP,SORCS3,ATP2B2,SON,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,GRIA2,GRM3,OMG,TLL2,CELF3,LGI1,PIK3CD,MICAL1,DOCK7,CTNND2,FAM131B,KIAA0408,WBP1L,CA10,MAGI2,PLPPR4,SRGAP3,PAK5,TTLL7,RNF220,EFNA3,ELAVL3,EPB41" MicroRNA "TGTTTAC,MIR-30D:MSigDB" "TGTTTAC,MIR-30D:MSigDB" MSigDB 2.69E-25 1.46E-21 1.59E-24 1.46E-23 48 543 "MAP6,SCN3A,SEMA6A,FOXG1,ITSN1,DGKZ,NLGN1,SLC1A2,SLC6A9,CADPS,SPHKAP,SORCS3,ATP2B2,SON,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,GRIA2,GRM3,OMG,TLL2,CELF3,LGI1,PIK3CD,MICAL1,DOCK7,CTNND2,FAM131B,KIAA0408,WBP1L,CA10,MAGI2,PLPPR4,SRGAP3,PAK5,TTLL7,RNF220,EFNA3,ELAVL3,EPB41" MicroRNA "TGTTTAC,MIR-30E-5P:MSigDB" "TGTTTAC,MIR-30E-5P:MSigDB" MSigDB 2.69E-25 1.46E-21 1.59E-24 1.46E-23 48 543 "MAP6,SCN3A,SEMA6A,FOXG1,ITSN1,DGKZ,NLGN1,SLC1A2,SLC6A9,CADPS,SPHKAP,SORCS3,ATP2B2,SON,ZCCHC24,JPH4,NCAM1,RGL1,NEUROD1,NKX2-2,CAMTA1,ADGRL3,ANO4,CACNB2,EML4,GRIA2,GRM3,OMG,TLL2,CELF3,LGI1,PIK3CD,MICAL1,DOCK7,CTNND2,FAM131B,KIAA0408,WBP1L,CA10,MAGI2,PLPPR4,SRGAP3,PAK5,TTLL7,RNF220,EFNA3,ELAVL3,EPB41" MicroRNA "TGCTGCT,MIR-15B:MSigDB" "TGCTGCT,MIR-15B:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA "TGCTGCT,MIR-195:MSigDB" "TGCTGCT,MIR-195:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA "TGCTGCT,MIR-424:MSigDB" "TGCTGCT,MIR-424:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA "TGCTGCT,MIR-497:MSigDB" "TGCTGCT,MIR-497:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA "TGCTGCT,MIR-15A:MSigDB" "TGCTGCT,MIR-15A:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA "TGCTGCT,MIR-16:MSigDB" "TGCTGCT,MIR-16:MSigDB" MSigDB 2.71E-25 1.47E-21 1.60E-24 1.46E-23 49 569 "SYNDIG1,EYA1,ARID1A,SLITRK1,SCN4B,ANK2,CNIH2,SH3GL2,PPM1E,NLGN1,LRRC55,ARHGAP5,ARFGAP2,ASPH,ATP2B2,GABBR1,SON,WDTC1,MYT1L,CAB39,ARPP21,KIF1B,BCL2L2,DCAF5,ACSBG1,VAMP1,BTRC,PSD3,GRIN1,OMG,TGFBR3,CDC42,PCDH9,DCLK1,CAMKV,VAV2,NXPH1,POU3F2,PPP2R5C,PPP3CB,PTHLH,COPS7A,CSDE1,PEX5,TMEM255A,PAK5,RET,SFXN5,ARHGAP12" MicroRNA hsa-miR-1275:mirSVR_highEffct hsa-miR-1275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-25 1.48E-21 1.61E-24 1.47E-23 60 882 "ACHE,ACLY,ATAT1,ARID1A,KCNIP2,CSMD3,NDRG2,ADAR,DSCAML1,GRAMD1B,FGF1,ANK2,ITSN1,PPM1E,GPAM,PKNOX2,NSG2,GAD2,JPH4,GANAB,VAMP1,SYT4,ROBO3,TCF12,EML4,PCDHGA3,NUMA1,GRIK2,GRM3,OLR1,LEFTY2,TGFBR3,INA,P2RX7,DCLK1,ZMYND8,SERPINE2,MEAF6,BEST1,POU3F2,CSF3R,FEZ1,OSBPL3,CTNND2,WBP1L,DNAJC6,CA10,PTHLH,CADM2,LRP8,PTPRO,KCNJ10,KCNMA1,PEX5,FAM66C,RALGDS,BSDC1,RFX4,INSYN2,PHC2" MicroRNA hsa-miR-143*:mirSVR_highEffct hsa-miR-143*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-25 1.56E-21 1.69E-24 1.55E-23 54 706 "SRARP,EYA1,FGF1,SLC30A10,ERICH3,APC,BCAS1,API5,RUFY2,CCDC88A,CADPS,ASPH,SORCS3,RCOR3,MYT1L,B3GALT2,ZSWIM8,ARPP21,IDI2-AS1,NPAS3,CLASP2,GLS,KAZN,CAMTA1,ANO4,GRIA1,ADAMTS8,CRB1,AIFM1,SEZ6L,TPM3,ADGRG1,SCRG1,TMPRSS5,ANO5,NLGN3,P2RY12,NSD2,CP,CHD1L,FEZ2,RBPJ,FMN2,CA10,PTHLH,HP1BP3,MAGI2,PLPPR4,PYGM,C12orf4,ZYG11B,RGS7,RAVER2,C2orf80" MicroRNA hsa-miR-199b-5p:mirSVR_highEffct hsa-miR-199b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.90E-25 1.57E-21 1.70E-24 1.56E-23 60 883 "ZFYVE27,MBP,RCSD1,ACTN2,CLIP1,KLHL32,ADD3,CDC7,TESK2,LRRTM4,KIAA1109,ERICH3,ASRGL1,ANK3,ITSN1,APBB1,NTNG1,NLGN1,SLC1A6,NSG2,SORCS3,SMARCE1,RCOR3,ATM,WDTC1,ENKUR,KIF1B,ADHFE1,RND1,CAMSAP2,ANO4,DDR1,ZEB1,GRIA2,GRIA4,CRB1,LGI1,PDE4B,TMPRSS5,CHRM1,CASC2,JAM2,PIK3CD,POU3F2,CHD1L,CRLS1,RGS6,PRKAB2,SYTL2,LRRTM3,LRP8,MAGI2,BLOC1S6,KCNK2,SUSD4,ABI1,FAM13C,RGS10,SEC61A2,ARHGAP12" MicroRNA hsa-miR-520a-5p:mirSVR_highEffct hsa-miR-520a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-25 1.69E-21 1.83E-24 1.68E-23 65 1042 "ACER3,RTN1,TUBB4A,ELMOD1,MOBP,SOX6,ASRGL1,STK32C,SHTN1,PAAF1,CAPRIN2,ASPH,RCOR3,SON,ILDR2,TTLL9,KIF1B,HEPN1,ACSBG1,PCDH11X,CAMTA1,NODAL,MMD2,KLHL4,GPM6B,CACNB2,GRIA2,GRIA4,OLR1,CRB1,CDC42,ZNF384,PDE3B,HERC2P3,JAM2,OPALIN,SULT4A1,PLXNB3,BTF3L4,NXPH1,CHD1L,RNF14,ATRNL1,FMN2,RAB39A,PKN2,USP54,ARHGEF4,NRSN1,TOX,SIRPA,CADM2,OCIAD1,TMCC2,KCNK2,PCDH15,KIF2A,TMEM255A,DPP6,RALGDS,SUSD4,PAK5,ZYG11B,EPB41L1,EPB41L2" MicroRNA hsa-miR-3132:mirSVR_lowEffct hsa-miR-3132:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-25 1.82E-21 1.97E-24 1.80E-23 73 1313 "ASIC1,WLS,RTKN,CSMD3,NDRG2,CLIP1,PLEKHG5,SORCS1,TUBB4A,CHST15,SNX32,FGF14,HPCAL4,MOBP,SOX6,CDC42BPA,SFMBT2,MSR1,PKNOX2,ADGRA1,EIF4G3,SCN3B,SOX5,CADM3,TTLL9,C11orf87,NDUFA5,GFAP,RGL1,ARHGEF7,ZNF638,NHLH1,CDK5R2,UNC5D,PSRC1,LRIT2,TCF7L2,PTBP2,ADAMTS8,GPR88,TF,OPCML,TGFBR3,TMEM257,DAAM2,TPD52,TPM3,PDE2A,CA14,GDAP1L1,POU3F2,FMN2,WBP1L,RIMS3,SPIRE1,LRRTM3,PRDM2,COPS7A,CSDE1,OLFM3,OCIAD1,PTPRD,PLPPR4,KCNC1,PTPRO,KCNH1,SRGAP3,KCNMA1,RASGRF1,JMJD1C,PIANP,EFNA3,UEVLD" MicroRNA hsa-miR-3126-3p:mirSVR_lowEffct hsa-miR-3126-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.66E-25 1.98E-21 2.14E-24 1.96E-23 74 1350 "RABEPK,TTYH1,SORCS1,LRRTM4,LRRC7,MOBP,MOG,SOX6,FOXM1,PI16,NLGN1,USP16,ZNF365,SLC7A14,SLC2A5,SLC6A9,DACH2,NAXD,ASPH,BRINP2,SORCS3,KBTBD12,NRG3,DKK3,MYBPC1,KIF21B,DNER,NFASC,DCAF5,PCDH11X,ANO4,ATF7,DDR1,NUDT21,GRIA1,CYB561A3,LINC00839,TGFBR3,ZDHHC22,DAAM2,REPS2,PADI2,TPD52,PIRT,ZMYND8,CHRM1,HNRNPK,FAM181B,CELF5,CHD1L,PPP3CB,FEZ1,OSBPL3,RBPJ,DZIP3,CMTM5,PLPPR1,RGMA,BLOC1S6,PTPRD,PTPRO,C1orf109,SRGAP3,RABGAP1L,KCNK2,KCNMA1,ZYG11B,CAMK1G,USH1C,RFX5,RGR,ATL1,ELAVL3,RASGRP2" MicroRNA hsa-miR-590-5p:mirSVR_lowEffct hsa-miR-590-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-25 2.13E-21 2.30E-24 2.11E-23 78 1495 "ACLY,MBP,RCSD1,GALNT13,FCGR1A,FOXG1,MOG,SOX6,FOXM1,USP28,PKP4,GPAM,NLGN1,MIER1,SLC7A14,MSR1,LRRC55,DACH2,TMEM249,ASCL1,CSPG5,ASPH,B3GAT1,TMEM108,SOX1,TTLL9,NCAM1,DCAF5,PHLDB1,NFIA,ZNF638,DDHD2,CNTN2,TMEM136,ANO4,CACNA1E,CRB1,TGFBR3,KCNK10,PC,PCDH8,LGI1,PCSK2,TMEFF2,ZFYVE9,PMP2,ACBD5,POU3F2,CHD1L,RNF14,PRKAB2,SDC3,FMN2,PKN2,USP54,NRSN1,NOS1AP,CADM2,SHD,MAGI2,CDH20,OCIAD1,SV2A,KCNJ10,KCNK1,KCNK2,DLG2,FAM66C,BSDC1,RET,RGS10,FAM135B,ATL1,SEC61A2,SLC39A12,RBM12,VWA5A,SLC4A10" MicroRNA hsa-miR-142-5p:PITA hsa-miR-142-5p:PITA_TOP PITA 4.40E-25 2.39E-21 2.57E-24 2.36E-23 55 741 "RTN1,GPR158,SCN3A,CDC42BPA,GAS7,SORBS1,ASCL1,CAPRIN2,PHYHIPL,SOX1,MYT1L,SOX5,RGL1,SEPT3,FAM168A,GLS,LUZP2,CAMTA1,CAMSAP2,ADGRL3,TCF12,CAMK2A,CECR2,PSD3,REPS2,TNS1,CHGA,CADM1,PIK3CD,TJP2,CELF5,SLC25A27,FAT3,TENM4,PKN2,FAM131B,TOX,ITGAV,RGMA,MAGI2,PTPRD,DLG2,DLG3,TMEM255A,ATG16L1,ABI1,GOPC,L1CAM,JMJD1C,SFXN5,RBM12,ABI2,ELAVL4,TMEM100,BAALC" MicroRNA hsa-miR-1908:mirSVR_lowEffct hsa-miR-1908:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.57E-25 2.47E-21 2.66E-24 2.44E-23 58 830 "DPF1,RABEPK,ACHE,SYT9,EXTL1,ATAT1,CLIP1,SLITRK1,ADORA1,AMER2,DISP3,PLA2G6,TRIM46,CNIH2,ITSN1,DGKZ,DGKD,BCAN,CLSTN1,MIER1,SLC1A7,MADD,SLC6A9,KBTBD12,ADGRA1,ALDH4A1,SNCB,WDTC1,SOX1,KIF21B,SOX10,TTLL9,CPLX2,RAP1GAP2,C11orf87,ALDH1L1,NCDN,RCOR2,PHLDB1,ARHGEF7,TBX15,ATF7,CACNA1E,CYB561A3,FBXL16,HRH3,HPSE2,ASIC3,GDAP1L1,CAMKV,VAV2,MICAL2,SDC3,PRKCG,DPYSL5,KCNJ11,SUSD4,RNF220" MicroRNA hsa-miR-26b*:mirSVR_highEffct hsa-miR-26b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.77E-25 2.59E-21 2.78E-24 2.55E-23 74 1356 "LOC100128239,ACER3,SYT9,LGR4,ACTN2,ADGRV1,LDLRAD3,MDM4,KLHL32,WAC,FGF1,SGIP1,PPFIA1,PKP4,GPAM,SYBU,NLGN1,API5,SHTN1,PAAF1,ARHGAP5,ASPH,RCOR3,NRG3,EIF4G3,TNIK,CAB39,ZSWIM8,NMNAT2,NPAS3,C11orf87,BCL2L2,GLS,CASTOR3,PCDH11X,GNAS,NODAL,PRUNE2,GPM6A,ZEB1,CLEC9A,NUDT21,SYT6,VSTM2A,CYB561A3,ZFP91,MAEL,PCDH9,ZNF384,PLEKHB1,CASC2,CADM1,PRRX1,P2RY12,SLC36A4,SF1,SNCAIP,TENM4,PPP3CB,NRSN1,MAPK10,EDRF1,ECE2,PLPPR5,CEP170,PCDH15,KCNN3,KLRC2,DTNA,SEC61A2,SLC4A10,ROM1,EPB41L1,LRRC23" MicroRNA hsa-miR-624*:mirSVR_highEffct hsa-miR-624*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-25 2.78E-21 2.98E-24 2.74E-23 57 802 "CSMD2,CSMD3,F3,ADD3,WAC,ERMN,ADORA3,NLGN4X,UNC79,ANK3,USP28,ST3GAL3,CCDC88A,NAXD,ASPH,CCDC181,PALLD,SON,SOX5,ARPP21,GART,NCAM1,NDUFA5,RGL1,GNAS,ADGRL3,PRUNE2,GPM6A,VWC2,DDR1,OMG,ZFP91,MAEL,PCDH8,LGI1,MAGI1,PRMT8,NSD2,CNRIP1,POU3F2,CHD1L,CRMP1,RNF14,MICAL2,DOCK7,SPIRE1,ZNF385B,CADM2,COPS7A,MAGI2,PTPRE,DLG3,C12orf4,SLC25A18,SH3GLB1,ARHGAP12,TMEM100" MicroRNA hsa-miR-3180-3p:mirSVR_lowEffct hsa-miR-3180-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.16E-25 2.80E-21 3.00E-24 2.75E-23 51 631 "DPF1,RTN3,SYNDIG1,EXTL1,FAM43B,ATAT1,FOXRED2,SEMA6C,ITSN1,NTNG1,DGKZ,MADD,SLC6A9,ATP1A3,SOX10,FXYD6,C11orf87,ALDH1L1,NCDN,SLCO1C1,CDK5R2,TBX15,ATF7,NEU4,NRGN,CAMK2G,BRSK2,GRIN1,PTPN5,USP2,FBXL16,ZDHHC22,IGSF21,HPSE2,PFKFB3,HPCA,NLGN3,CCSER2,PLCH2,FMN2,SIRPA,SMG7,AK5,KLRC3,SUSD4,L1CAM,ARHGEF10L,EEF1A2,CACNG7,EFNA3,OLIG2" MicroRNA hsa-miR-135b*:mirSVR_lowEffct hsa-miR-135b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.33E-25 2.88E-21 3.09E-24 2.84E-23 66 1085 "RABEPK,SERPINA3,LDLRAD3,CSMD3,SORCS1,ADORA1,NLGN4X,SEMA6A,FGR,UNC79,MOBP,SOX6,SESN3,AQP4,MIER1,BCO1,CADPS,ASCL1,TMEM108,TMEM151A,ATP2B2,ZCCHC24,ILDR2,SPART,NDUFA5,ZNF302,ARHGEF7,RHBDL3,GNG4,CACNA1A,PRUNE2,VWC2,NRGN,CECR2,CYB561A3,LINC00839,CRB1,TJP1,PADI2,HRH3,SEZ6L,TPM3,ZNF384,PRMT8,PFKFB3,NLGN3,NEGR1,ANLN,UBTF,ST8SIA5,SNCAIP,RGS6,ATRNL1,CMTM5,KIAA0408,PHYHIP,ITGAV,JAKMIP2,PRTFDC1,CEP170,CCDC3,SLC17A6,DTNA,ABCC9,RGR,PHC2" MicroRNA hsa-miR-3142:mirSVR_highEffct hsa-miR-3142:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.55E-25 3.00E-21 3.22E-24 2.95E-23 51 632 "SERPINA3,ZFYVE27,RCSD1,EYA1,HOGA1,TESK2,LRRTM4,FGF1,SEMA6C,ANK2,PPFIA1,PKP4,NTNG1,RUFY2,MT3,DKK3,SON,ILDR2,AHCYL1,DNER,LMO3,DCAF5,CAMSAP2,GOLGB1,TCF12,GRIA2,GRIA4,LGI1,CASC2,JAM2,SEMA5B,ANLN,PMP2,NSD2,SF1,MICAL2,VCAN,DNAJC6,BDNF-AS,OLFM3,PTPRE,KCNK2,KCNMA1,DLG2,DTNA,SLC6A15,SEC61A2,RPRD1A,SLC4A10,YY1AP1,RASGRP2" MicroRNA hsa-miR-1274b:mirSVR_lowEffct hsa-miR-1274b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.85E-25 3.17E-21 3.39E-24 3.11E-23 67 1120 "ZFYVE27,MBP,CSMD3,RXRG,WAC,FABP7,SLC44A5,TESK2,SCN3A,FGF1,ASIC4,ELMOD1,SFPQ,CNIH2,ITSN1,ANXA7,BCAN,CACHD1,ZNF365,RUFY2,LRRC55,SLCO1A2,BRINP2,SNAP25,SON,NMNAT2,KIF1B,ERBIN,GJB1,SEPT3,AJAP1,GLS,LUZP2,UNC5D,ADGRL3,GRIK2,GRIK3,CRB1,ZFP91,PCDH9,PRMT8,PLEKHB1,CADM1,NRXN1,VAV2,C11orf49,BEST1,SNCAIP,ATRNL1,DOCK7,KIAA1755,NRSN1,EDRF1,ZNF385B,LRRTM3,BDNF-AS,ZC3H11A,SRGAP3,KCNK1,NAV2,PAK5,L1CAM,BSDC1,USH1C,ARHGAP12,EPB41L1,EPB41L2" MicroRNA hsa-miR-3159:mirSVR_highEffct hsa-miR-3159:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.47E-25 3.50E-21 3.74E-24 3.43E-23 65 1056 "EPS8,SDE2,RPL38,SORCS1,ERMN,FCGR1A,LRRC7,FGF14,SOX6,NTNG1,MAGI3,CAPRIN2,ASPH,BRINP2,SMARCE1,ATM,DKK3,AHCYL1,NAP1L2,CLASP2,DCAF5,NEUROD1,DDHD2,NODAL,CAMSAP2,CNTN2,TCF12,PTBP2,VSTM2A,GUCY1A2,TMEM257,ZFP91,PDE3B,LINC01102,ANO5,CNTN1,PMP2,MEAF6,CHD1L,CRMP1,ATRNL1,VCAN,IGSF1,CTNND1,PUM1,TOX,ELMO1,PRDM2,HP1BP3,COPS7A,CEP170,PTPRD,NTM,KIF2A,HS3ST4,TMEM255A,RALGDS,ABCC9,SLC6A15,FAM135B,VANGL2,SSPN,SLC4A10,TMEM100,BAALC" MicroRNA hsa-miR-609:mirSVR_lowEffct hsa-miR-609:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.64E-25 3.60E-21 3.84E-24 3.52E-23 64 1024 "MBP,LDLRAD3,CLIP1,LRRC7,TRIM46,SGIP1,NTNG1,ZNF365,RUFY2,SLC8A3,DLL3,ASPH,TMEM108,NRG3,PALLD,GABBR1,MYT1L,ARPP21,TTLL9,KIF1B,FXYD6,C11orf87,CLASP2,SMOC1,NCDN,UNC5D,CACNB2,LILRA1,PRLHR,GRIA2,OPCML,TGFBR3,TMEM257,MAEL,CDC42,RBFOX2,PRMT8,FNDC5,LRTM2,CHGA,CHRNB2,FTO,PLXNB3,BTF3L4,PMS2,PPP3CB,MASP1,PTCH1,CEP170,PTPRD,PTPRZ1,KCNJ9,KCNK2,RAB3IL1,FAM66C,ATG16L1,C12orf4,GNE,DTNA,NUP214,RGS7,PIANP,EN2,EPB41L2" MicroRNA hsa-miR-182:PITA hsa-miR-182:PITA_TOP PITA 6.97E-25 3.78E-21 4.03E-24 3.69E-23 45 479 "ADCY2,ADD3,SNX30,GPR158,LRRC7,PDZD4,CDC42BPA,ANK3,PPM1E,DOCK10,NTNG1,SLC1A2,ARHGAP5,TAGLN3,PALLD,MYT1L,ZCCHC24,AHCYL1,NELL1,NKX2-2,CAMTA1,CAMSAP2,ADGRL3,PC,TNS1,PCDH8,ANLN,NMT2,VAV2,FAT3,MED1,TENM4,PKN2,RIMS3,PTCH1,CA10,CADM2,ELMO1,DLG2,DLG3,WIPF2,RALGDS,DSCAM,RTN4,L1CAM" MicroRNA hsa-miR-487a:mirSVR_highEffct hsa-miR-487a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.00E-25 3.79E-21 4.04E-24 3.70E-23 64 1025 "LGR4,WLS,CSMD3,AGT,LRRC7,CDC42BPA,PPFIA1,ITSN1,PKP4,MAGI3,RPH3A,ARFGAP2,YPEL4,CCDC88A,ASTN1,SON,SOX5,KIF21B,GAD2,NPAS3,ERBIN,ZNF638,SYT4,ADGRL3,GPM6A,CACNB2,ZEB1,PTBP2,GRIA4,MFSD2A,REPS2,C1orf94,LGI1,MAGI1,ANO5,TMEFF2,ST8SIA5,SULT4A1,SLC25A27,SPATA6,PPP3CB,KCNT2,ATRNL1,PRKACB,IGSF1,TOX,ANKS1B,MAGI2,ZC3H11A,SMG7,PLPPR4,KCNC1,PTPRZ1,PCDH15,KCNMA1,GOPC,FAM13C,DTNA,RFX5,JMJD1C,ZNF248,SEC61A2,RNF220,SSPN" MicroRNA hsa-miR-548s:mirSVR_lowEffct hsa-miR-548s:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.37E-25 4.53E-21 4.82E-24 4.43E-23 84 1738 "TTYH1,LOC100128239,MBP,ADGRV1,WLS,RTKN,KCNIP2,ADD3,ERMN,GPR158,HOGA1,DISP3,RASA3,USP28,JAKMIP3,MSR1,PKNOX2,SLC8A3,SHANK2,SLC14A1,DACH2,CGREF1,ATM,SON,CPLX2,NCAM1,BCL2L2,ALDH1L1,KIRREL3,ZNF638,NKX2-2,GNAS,MMD2,BTRC,GOLGB1,TMEM136,ANO4,ADAMTS8,OPCML,LINC00839,CRB1,LEFTY2,GUCY1A1,TLL2,KCNK10,MAEL,PCDH9,LGI1,TPD52,TPM4,IGFN1,ZMYND8,FNDC5,PLEKHB1,GDAP1L1,CAMKV,CCDC136,CNTN1,FAT3,ATCAY,SF1,PTPA,DOCK7,SDC3,PRKCG,PRKCZ,ITGAV,PTHLH,CEP170,PTPRD,RABGAP1L,KCNJ10,KCNK1,PCDH15,DPP6,SLC6A15,CAMK1G,NUP214,ARHGEF10L,ZNF248,VANGL2,SEC61A2,SIDT2,UEVLD" MicroRNA hsa-miR-582-5p:TargetScan hsa-miR-582-5p TargetScan 8.61E-25 4.66E-21 4.96E-24 4.55E-23 44 457 "EPS8,RIMKLA,LGR4,MRVI1,ERMN,GRAMD1B,SCN4B,LRRC7,FOXG1,ANK1,ITSN1,APC,AQP4,MIER1,B3GAT1,MYT1L,NPAS3,NFASC,C11orf87,FAM168A,NFIA,ABCC8,CAMSAP2,GOLGB1,ACSL6,BRSK2,GRID1,CD81,RBFOX2,HMGB1,HNRNPK,PRKACB,DPYSL5,LRRTM3,JAKMIP2,PMEPA1,RGMA,KCND3,KCNN3,PEX5,RTN4,ABI2,ELAVL3,PRRT4" MicroRNA hsa-miR-505*:mirSVR_highEffct hsa-miR-505*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.82E-25 5.32E-21 5.65E-24 5.18E-23 51 640 "TTYH1,SYT9,CSMD3,PKP4,APC,RUFY2,MSR1,NSG2,SORCS3,RCOR3,TNIK,ENKUR,JPH4,TTLL9,FXYD6,NELL1,ZNF638,MMD2,GRIA2,GRIA4,SPX,CDH8,PRMT8,BEST3,JAM2,SEMA5B,A2ML1,C11orf49,SLC36A4,FAAP20,MFSD4A,SF1,CRMP1,PPP2R5C,MICAL2,EDRF1,FGFR1OP2,SYTL2,ZNF385B,CA10,BDNF-AS,HP1BP3,BLOC1S6,ZC3H11A,KCNK2,DNAH9,SLC25A18,SUSD4,PHC2,SYT15,FGFBP3" MicroRNA hsa-miR-145*:mirSVR_highEffct hsa-miR-145*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-24 5.87E-21 6.22E-24 5.71E-23 62 969 "CSMD2,NDRG2,FABP7,CHST15,SNX32,MOBP,FOLH1,ITSN1,PKP4,NTNG1,MAGI3,GPAM,SLC1A7,SLC2A5,RUFY2,MSR1,SLC8A3,CCDC88A,RCOR3,NRG3,USP33,B4GALNT1,ARPP21,TTLL9,KIF1B,SPART,CLASP2,NELL1,NEUROD1,GANAB,GLS,VAMP1,DDHD2,CAMTA1,CAMK2G,GRIA1,GRIA2,GRIK2,OLR1,ZFP91,PIRT,BEST3,RNF14,RBPJ,CTNND1,PUM1,MASP1,ZNF385B,SYNC,PLPPR1,BLOC1S6,PTPRD,SMG7,PLPPR4,NTM,PCDH15,RAD52,FAM57B,FAM13C,ELAVL4,RCAN2,BAALC" MicroRNA hsa-miR-18b:mirSVR_highEffct hsa-miR-18b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.08E-24 5.87E-21 6.22E-24 5.71E-23 54 726 "SLC25A25,ADD3,AMER2,GPR158,LINC00461,FGF1,BCAR3,ANK3,FOLH1,ITSN1,ANXA7,MAGI3,ZNF365,B3GAT1,ATM,SON,CAB39,IDI2-AS1,SPART,C11orf87,GNAS,GPM6A,GPM6B,GPR88,TJP1,TLL2,DAAM2,MAEL,CDC42,PDE1A,CASC2,NRXN1,SLC25A27,COL9A2,PRRX1,RNF14,PPP3CB,RGS6,ATRNL1,PRKACB,DZIP3,NRSN1,PUM1,MASP1,TOMM20,SYNC,CADM2,HP1BP3,TMCC2,INSYN2,ARHGEF10L,SYT15,CBLN2,EPB41L1" MicroRNA hsa-miR-649:mirSVR_highEffct hsa-miR-649:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-24 6.20E-21 6.56E-24 6.02E-23 62 970 "ACER3,ACTN2,FAM43B,WAC,SORCS1,AMPH,SGIP1,CDC42BPA,SORBS1,API5,SHTN1,CCDC88A,TMEM108,ATM,NRG3,PALLD,DKK3,MYT1L,SOX5,NCAM1,LMO3,NDUFA5,SLCO1C1,SYT4,CAMSAP2,ADGRL3,ANO4,GPM6B,ZEB1,CECR2,NUMA1,GRIK2,TMEM257,CDH10,HMGB1,JAM2,SERPINE2,CADM1,ANLN,SLC25A27,CP,KCNT2,ATRNL1,PRKAB2,CTNND2,NRSN1,EDRF1,ANKS1B,GON4L,PSMD13,CEP170,BLOC1S6,KCNK1,RAD52,DPP6,RASGRF1,SLC6A15,ZYG11B,ARHGEF10L,ZNF248,TTLL7,ELAVL3" MicroRNA hsa-miR-331-5p:mirSVR_lowEffct hsa-miR-331-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-24 6.29E-21 6.65E-24 6.10E-23 70 1236 "ABAT,ACER3,ASIC1,SYT9,RTN3,CLIP1,DSCAML1,ADD3,SORCS1,SNX30,GPR158,KIAA1109,GOLGA7B,BCAN,SORBS1,BCAS1,SLC14A1,SPHKAP,ASTN1,CAB39,ILDR2,ENKUR,NEUROD1,CAMTA1,GNG4,CNTN2,ZEB1,AZIN2,GRIA4,LEFTY2,GUCY1A1,TJP1,PAH,PAX6,PCDH9,PLEKHB1,MS4A7,SEMA5B,ANLN,SULT4A1,PMP2,CELF5,PPP3CB,RBPJ,KIAA1755,TUBB2B,ITGAV,CA10,PTHLH,HP1BP3,COPS7A,PTPRO,PTPRZ1,SRGAP3,KCNK2,PCDH15,PEX5,SLC17A6,RAD52,ABI1,RASGRF1,FAM13C,TTLL7,SEC61A2,SIDT2,ARHGAP12,SLC4A10,ELAVL4,EN2,UEVLD" MicroRNA hsa-miR-627:mirSVR_lowEffct hsa-miR-627:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-24 6.52E-21 6.88E-24 6.31E-23 75 1413 "ABAT,KLHL32,FABP7,TESK2,KIAA1109,SLITRK3,NLGN1,ST3GAL3,AQP4,MSR1,YPEL4,CCDC88A,NAXD,SORCS3,B3GAT1,EIF4G3,DKK3,SCN3B,CADM3,NMNAT2,SALL3,NPAS3,ALDH1L1,GFAP,DCAF5,PHLDB1,RHBDL3,NHLH1,NUDT21,CAMK2G,TMEM151B,VXN,GRIA4,TGFBR3,P2RX7,REPS2,PC,SEZ6L,PDE3B,HMGB1,TUB,TMEFF2,JAM2,NRXN1,CPT1C,A2ML1,DNAJC12,ST8SIA5,FTO,CHD1L,PPP2R5C,SNCAIP,TENM4,FEZ1,MICAL2,DOCK7,ANKS1B,LRRTM3,COPS7A,CEP170,STMN4,OCIAD1,PCDH15,KCNMA1,NAV2,WIPF2,DNM2,SUSD4,DBX2,DTNA,ZNF248,RLBP1,SIDT2,EPB41L2,RASGRP2" MicroRNA hsa-miR-520f:mirSVR_highEffct hsa-miR-520f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-24 6.59E-21 6.95E-24 6.38E-23 70 1237 "EPS8,TMEM74,ATAT1,RTKN,F3,SLITRK1,ERMN,AMER2,LRRTM4,LINC00461,ANK1,ANK2,MAGI3,SLITRK3,API5,USP16,AQP4,MIER1,SLC1A7,RCOR3,TMEM108,AHCYL1,KIF1B,LMO3,NELL1,RGL1,CAMSAP2,UNC5D,ADGRL3,LILRA1,TCF7L2,ZEB1,PTBP2,VXN,NUMA1,OLR1,LEFTY2,TMEM257,C1orf94,PCDH9,LGI1,MAGI1,CCSER2,PRRX1,ACBD5,CNRIP1,POU3F2,ATRNL1,RBPJ,PKN2,TOX,SYNC,PRDM2,PRTFDC1,HP1BP3,RGMA,ZC3H11A,OLFM3,PTPRE,PCDH15,KCNMA1,KCNN3,HS3ST4,C12orf4,FAM13C,DTNA,PAK5,RET,SLC4A10,RPE65" MicroRNA hsa-miR-708*:mirSVR_highEffct hsa-miR-708*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-24 7.05E-21 7.43E-24 6.81E-23 68 1170 "LDLRAD3,ADD3,SORCS1,ADORA3,KIAA1109,LRRC7,FGF14,FGR,UNC79,ERICH3,MAGI3,AQP4,MIER1,DACH2,SMARCE1,SNAP25,PHYHIPL,GABBR1,NMNAT2,CLASP2,ERBIN,GLS,DDHD2,UNC5D,GPM6A,ATF7,ZEB1,CLEC9A,EML4,CAMK2A,GRIA2,LINC00839,TJP1,DAAM2,CDC42,LGI1,PRMT8,HMGB1,SCRG1,TMEFF2,CADM1,KIAA1549L,FTO,MEAF6,SLC25A27,BTF3L4,PPP2R5C,PRKACB,PLD5,IGSF1,MAPK10,LRRTM3,ITGAV,PLPPR1,CADM2,COPS7A,BLOC1S6,OLFM3,KCNC1,PTPRO,PTPRZ1,PCDH15,PEX5,DPP6,GOPC,DBX2,DTNA,EPB41" MicroRNA hsa-miR-3136:mirSVR_highEffct hsa-miR-3136:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-24 8.30E-21 8.74E-24 8.02E-23 70 1242 "LGR4,ATAT1,MDM4,ADAR,FABP7,SORCS1,ADORA3,AMER2,CHST15,KIAA1109,FGF1,ANK2,ANK3,ITSN1,PKP4,SH3GL2,RUFY2,MSR1,LRRC55,SMARCE1,DKK3,SCN3B,SOX1,NCAM1,STOX1,KIRREL3,AJAP1,PCDH11X,ZNF638,DCLK2,VWC2,CACNB2,EML4,CECR2,GRIA4,GPR88,CRB1,TGFBR3,AIFM1,CDC42,PCDH9,TPM3,PDYN,BEST3,CADM1,NEGR1,NXPH1,SF1,PPP2R5C,ATRNL1,VCAN,PHACTR3,DZIP3,PKN2,USP54,CTNND1,BRINP3,TOX,CADM2,PRDM2,KCNMA1,DLG2,SLC17A6,ABI1,DSCAM,DTNA,RTN4,RGS7,RLBP1,RCAN2" MicroRNA hsa-miR-4313:mirSVR_lowEffct hsa-miR-4313:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-24 8.69E-21 9.14E-24 8.38E-23 70 1243 "TTYH1,EMID1,MEG3,MRVI1,ADARB2,SNX32,KIAA1109,GOLGA7B,TRIM46,RASA3,CNIH2,SLITRK3,ST3GAL3,BCAS1,MADD,SLC14A1,CADPS,PDE8B,SCG3,WDTC1,SOX10,TTLL9,NPAS3,RND1,HAP1,NUMA1,GRIA2,GRID1,PTPN5,USP2,MFSD2A,P2RX7,TLL2,TNR,PDE4B,ZMYND8,TMEFF2,PHKG1,CADM1,NRXN2,CAMKV,UBTF,A2ML1,TJP2,ST8SIA5,BEST1,NECAB2,MED1,CRLS1,NKAIN4,MICAL2,CMTM5,MAPK10,WBP1L,COPS7A,CCDC3,PEX5,SLC25A18,RASGRF1,L1CAM,BSDC1,NUP214,RET,FAM135B,INSYN2,RNF220,CACNG7,LMO1,EN2,SEZ6" MicroRNA hsa-miR-3150:mirSVR_highEffct hsa-miR-3150:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-24 8.80E-21 9.24E-24 8.48E-23 57 821 "RABEPK,SERPINA3,ADCY2,GRAMD1B,ADORA3,NLGN4X,SNX32,TESK2,ACTL6B,TRIM46,ITSN1,NTNG1,BCAS1,API5,SLC1A7,ARFGAP2,MT3,NSG2,SORCS3,SNCB,B4GALNT1,ARPP21,C11orf87,BCL2L2,ALDH1L1,NCDN,FAM168A,UNC5D,PRLHR,SYT6,PADI2,ZNF384,BEST3,HPSE2,BTF3L4,COL9A2,POU3F2,SF1,MICAL2,VCAN,PRKACB,KLK6,ACY3,PLPPR5,MAGI2,SMG7,KCNC1,SV2A,TMCC2,PEX5,RAB5B,KLRC2,RASGRF1,BSDC1,SEC61A2,PIANP,RPRD1A" MicroRNA hsa-miR-550*:mirSVR_lowEffct hsa-miR-550*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-24 9.10E-21 9.55E-24 8.76E-23 70 1244 "EPS8,CSMD2,WLS,RTKN,KCNIP2,CSMD3,F3,ADD3,NLGN4X,TESK2,LRRC7,SEMA6A,ELMOD1,MOBP,MOG,AMPH,ANK1,CCDC80,NSG2,DDX25,SON,KIF21B,DNER,NCAM1,RCOR2,ARHGEF7,CASTOR3,GNAS,DDHD2,UNC5D,CACNA1E,CACNB2,TCF12,PTBP2,GRIA1,GRIA2,GUCY1A1,ZFP91,PCDH9,TPM3,MAGI1,ZNF384,PDE2A,HMGB1,SCRG1,HNRNPK,CADM1,ANLN,BTF3L4,PRRX1,PPP3CB,FEZ1,PHACTR3,DOCK7,PLD5,PRKCZ,USP54,PUM1,EDRF1,ZNF385B,PSMD13,PRTFDC1,KCNA4,KCNK1,PCDH15,ABI1,JMJD1C,EFNA3,VWA5A,ARHGAP12" MicroRNA hsa-miR-1288:mirSVR_lowEffct hsa-miR-1288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-24 9.21E-21 9.65E-24 8.86E-23 65 1075 "MBP,SYT9,SYNDIG1,EXTL1,ADAR,RTN1,SORCS1,ADORA1,DOCK10,SFMBT2,BCO1,MSRA,SORCS3,ASTN1,B3GAT1,USP33,SON,B4GALNT1,IDI2-AS1,BCL2L2,STOX1,VAMP1,CAMTA1,CDK5R2,ADGRL3,WWC1,PRUNE2,CACNB2,CAMK2G,GRID1,CYB561A3,VWCE,INA,TMEM257,CD81,PCDH9,LGI1,TPD52,PCSK2,PRMT8,LINC01102,PDYN,PLEKHB1,CASC2,CCDC136,C11orf49,BEST1,CRMP1,NCAN,RIMS4,MAPK8,FAM131B,TOX,WBP1L,GON4L,KCNA4,SV2A,KCNJ9,DNM2,RASGRF1,DBX2,JMJD1C,ZNF248,SEC61A2,SLC4A10" MicroRNA hsa-miR-2117:mirSVR_highEffct hsa-miR-2117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-24 9.32E-21 9.76E-24 8.96E-23 67 1142 "ACER3,MAP6,LGR4,MDM4,KLHL32,SLITRK1,BCAR3,UNC79,PPFIA1,ITSN1,PKP4,SH3GL2,DOCK10,NLGN1,SLCO1A2,SORCS3,TNIK,SOX5,GAD2,TTLL9,NFASC,NDUFA5,RGL1,SLCO1C1,GLS,ZNF638,KAZN,DDHD2,TMEM136,KLHL4,TBX15,GPM6B,DDR1,TCF12,GRIA4,GRIK2,GPR88,LINC00839,LEFTY2,FBXL16,PDE4B,CA14,HERC2P3,MEAF6,SPATA6,POU3F2,SNCAIP,OSBPL3,PRKACB,DOCK7,RAB39A,USP54,CTNND1,EDRF1,MASP1,TOMM20,DNAJC6,JAKMIP2,AK5,KCNMA1,RAB5B,SLC17A6,GOPC,DSCAM,PAK5,ABI2,EN2" MicroRNA hsa-miR-26b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-24 9.38E-21 9.81E-24 9.00E-23 87 1874 "SDE2,PRR5L,PAQR6,CEND1,ATAT1,WLS,F3,KLRC4,TMEM156,NLGN4X,FCGR1B,CHST15,AGT,LRRTM4,SLC30A10,FOXG1,FOXM1,SFPQ,FOLH1,SH3GL2,DOCK10,NTNG1,DGKZ,CLSTN1,SLC1A6,MADD,SLC6A9,CSPG5,TAGLN3,DDX25,SORCS3,SMARCE1,CCDC181,ATP1A3,GABBR1,MYBPC1,MYT1L,SOX5,KIF21B,KIF1B,NDUFA5,ERBIN,INKA2,ASTN2,NKX2-2,CACNB2,GPR17,TCF12,NRDC,BRSK2,GRIK2,AIFM1,LILRA4,TPM3,PDE4B,HMGB1,PFKFB3,TUB,TLX1,JAM2,CADM1,CCSER2,FADS2,DNAJC12,MEAF6,SPATA6,ACBD5,PLCH2,SDC3,KIAA0408,TOX,DNAJC6,PTPRO,RABGAP1L,TMCC2,ARNT2,KCNQ2,CAB39L,KLRC2,SLC17A6,PARP11,RASGRF1,L1CAM,VANGL2,SEC61A2,ELAVL3,ROM1" MicroRNA hsa-miR-192*:mirSVR_lowEffct hsa-miR-192*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-24 9.53E-21 9.96E-24 9.14E-23 74 1386 "CDHR1,TMEM74,DUSP27,ACTN2,RTKN,CSMD3,ADCY2,SORCS1,ERMN,ADORA3,AMER2,TOMM40L,LRRC7,UNC79,AMPH,PPFIA1,PPM1E,CCDC80,CACHD1,PAAF1,MIER1,ARHGAP5,SLC8A3,TNIK,SOX5,KIF21B,ENKUR,B4GALNT1,BCL2L2,SMOC1,GLS,DDHD2,ADGRL3,CNDP1,CACNA1E,VSTM2A,GRIA2,GRIK2,CRB1,REPS2,C1orf94,PCSK2,PDE3B,CADM1,A2ML1,PTPA,SNCAIP,PRKACB,CTNND1,ITGAV,HP1BP3,CEP170,KCNA4,PTPRD,SV2A,KCNJ10,KCNK1,PCDH15,KCNMA1,DLG2,PID1,KLRC3,PARP11,RTN4,ABCC9,RFX4,JMJD1C,TTLL7,SYT15,SSPN,CBLN2,RAVER2,EPB41,BAALC" MicroRNA hsa-miR-107:mirSVR_highEffct hsa-miR-107:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.81E-24 9.78E-21 1.02E-23 9.36E-23 67 1143 "SYNDIG1,MDM4,KCNIP2,CSMD3,CLIP1,GALNT13,ERMN,FCGR1A,SCN3A,KIAA1109,BBOX1,ANK1,ANK3,USP28,ITSN1,SH3GL2,PPM1E,GPAM,NLGN1,BCAS1,PAAF1,ZNF365,ASPH,SMARCE1,PHYHIPL,CAB39,ENKUR,ARPP21,NPAS3,NCAM1,GFAP,NELL1,ACSBG1,OS9,ADGRL3,CACNA1E,PTBP2,VSTM2A,TF,CRB1,TGFBR3,TJP1,AIFM1,PCDH8,PDE3B,PRMT8,CASC2,SULT4A1,P2RY12,MICAL2,ATRNL1,VCAN,CTNND1,JAKMIP2,CNIH3,PTPRD,KCNK1,KCNK2,PEX5,WIPF2,PID1,GOPC,DTNA,RET,RFX4,TTLL7,RBM12" MicroRNA hsa-miR-103:mirSVR_highEffct hsa-miR-103:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.81E-24 9.78E-21 1.02E-23 9.36E-23 67 1143 "SYNDIG1,MDM4,KCNIP2,CSMD3,CLIP1,GALNT13,ERMN,FCGR1A,SCN3A,KIAA1109,BBOX1,ANK1,ANK3,USP28,ITSN1,SH3GL2,PPM1E,GPAM,NLGN1,BCAS1,PAAF1,ZNF365,ASPH,SMARCE1,PHYHIPL,CAB39,ENKUR,ARPP21,NPAS3,NCAM1,GFAP,NELL1,ACSBG1,OS9,ADGRL3,CACNA1E,PTBP2,VSTM2A,TF,CRB1,TGFBR3,TJP1,AIFM1,PCDH8,PDE3B,PRMT8,CASC2,SULT4A1,P2RY12,MICAL2,ATRNL1,VCAN,CTNND1,JAKMIP2,CNIH3,PTPRD,KCNK1,KCNK2,PEX5,WIPF2,PID1,GOPC,DTNA,RET,RFX4,TTLL7,RBM12" MicroRNA hsa-miR-302e:mirSVR_highEffct hsa-miR-302e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.98E-24 1.07E-20 1.12E-23 1.02E-22 65 1078 "EPS8,LGR4,AMER2,GPR158,ANK2,MAGI3,SLITRK3,API5,CLSTN1,USP16,SLC14A1,ASPH,RCOR3,MYT1L,TNIK,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,SLCO1C1,CAMTA1,UNC5D,GPM6A,ZEB1,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,HPS5,TNS1,PCDH9,MAGI1,TLX1,PRRX1,SPATA6,ACBD5,CNRIP1,PPP2R5C,FEZ2,PRKACB,FMN2,PKN2,MASP1,TOX,SYNC,PTHLH,CADM2,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,PTPRD,PTPRO,KCNMA1,HS3ST4,FAM13C,PAK5,ABCC9,SLC6A15,CRTAC1,TMEM100" MicroRNA hsa-miR-153:mirSVR_lowEffct hsa-miR-153:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-24 1.12E-20 1.16E-23 1.07E-22 80 1610 "CNTNAP3,ATAT1,ARID1A,KCNIP2,CSMD3,ADCY2,DSCAML1,AMER2,CHST15,UNC79,SLC30A10,AMPH,ANK3,DOCK10,TACC2,SORBS1,ST3GAL3,SHTN1,AQP4,ZNF365,MIER1,ARHGAP5,DACH2,SLIT1,SORCS3,PALLD,MEGF11,USP33,NEK6,NPAS3,NDUFA5,NFIA,SYT4,PRUNE2,GPM6B,DDR1,AZIN2,CAMK2G,GRIA2,ADAMTS8,OMG,TMEM25,MFSD2A,CELF3,PCDH8,ARHGAP19,LGI1,PDE3B,PDYN,MS4A7,HNRNPK,ANLN,PRRX1,MFSD4A,CRLS1,PPP2R5C,PPP3CB,RGS6,RBPJ,PRKAB2,PRKACB,KIAA1755,MASP1,LRP8,COPS7A,CEP170,KCNA4,KCNA6,PLPPR4,KCNK1,WIPF2,RTN4,ABCC9,FAM135B,TTLL7,RERGL,ABI2,SLC4A10,UEVLD,BAALC" MicroRNA hsa-miR-302f:mirSVR_lowEffct hsa-miR-302f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-24 1.13E-20 1.18E-23 1.08E-22 81 1648 "ACER3,ADGRV1,EYA1,CSMD3,F3,ERMN,HOGA1,TESK2,UNC79,ITSN1,NTNG1,MAGI3,SORBS1,SYBU,STK32C,RUFY2,SLC8A3,DACH2,PDE8B,BRINP2,NRG3,PHYHIPL,SON,SOX1,NCAM1,C11orf87,NFIA,PCDH11X,ZNF638,CAMTA1,NODAL,TBX15,ACSL6,CACNA1E,TCF12,NRDC,NUDT21,CAMK2G,VXN,VSTM2A,GRIK2,GUCY1A1,PAX6,CDC42,CDH10,LGI1,PDYN,CADM1,NEGR1,NMT2,DNAJC12,PLXNB3,PMP2,SLC36A4,MICAL2,RBPJ,PRKACB,PRKCG,BRINP3,RIMS3,GON4L,PLPPR5,ZNF385B,PSMD13,JAKMIP2,PTHLH,HP1BP3,COPS7A,NTM,DLG2,RAB5B,RAD52,DTNA,RTN4,FAM135B,PHC2,SLC39A12,SH3GLB1,RERGL,SLC4A10,EPB41" MicroRNA hsa-miR-133a:mirSVR_lowEffct hsa-miR-133a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-24 1.19E-20 1.23E-23 1.13E-22 67 1147 "CNTNAP3,DUSP27,IL17D,FAM43B,CSMD3,CDC7,SNX32,FGF1,FOXG1,SFPQ,RASA3,NTNG1,PAAF1,ZNF365,SLC8A2,CAPRIN2,ATM,NRG3,ATP2B2,LHFPL4,KIF1B,BCL2L2,NELL1,NEUROD1,VAMP1,ZNF638,OS9,DCLK2,TCF7L2,PCDHGA3,GRIA2,DAAM2,CDH8,PDE1A,PDE3B,PFKFB3,DLGAP3,SEMA5B,FADS2,CELF5,BTF3L4,COL9A2,NSD2,FAT3,TENM4,FMN2,PRKCZ,SLC45A1,IGSF1,NRSN1,ANKS1B,GON4L,DNAJC6,MAGI2,STMN4,KCNA4,KCNA6,AK5,KCNJ9,KCNK2,WIPF2,FAM66C,RET,SFXN5,EFNA3,CBLN2,SLC4A10" MicroRNA hsa-miR-133b:mirSVR_lowEffct hsa-miR-133b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-24 1.19E-20 1.23E-23 1.13E-22 67 1147 "CNTNAP3,DUSP27,IL17D,FAM43B,CSMD3,CDC7,SNX32,FGF1,FOXG1,SFPQ,RASA3,NTNG1,PAAF1,ZNF365,SLC8A2,CAPRIN2,ATM,NRG3,ATP2B2,LHFPL4,KIF1B,BCL2L2,NELL1,NEUROD1,VAMP1,ZNF638,OS9,DCLK2,TCF7L2,PCDHGA3,GRIA2,DAAM2,CDH8,PDE1A,PDE3B,PFKFB3,DLGAP3,SEMA5B,FADS2,CELF5,BTF3L4,COL9A2,NSD2,FAT3,TENM4,FMN2,PRKCZ,SLC45A1,IGSF1,NRSN1,ANKS1B,GON4L,DNAJC6,MAGI2,STMN4,KCNA4,KCNA6,AK5,KCNJ9,KCNK2,WIPF2,FAM66C,RET,SFXN5,EFNA3,CBLN2,SLC4A10" MicroRNA hsa-miR-124:PITA hsa-miR-124:PITA_TOP PITA 2.19E-24 1.19E-20 1.23E-23 1.13E-22 53 708 "EPS8,ACHE,CLIP1,RYR1,SORCS1,SCN4B,SEMA6A,GPAM,SLITRK3,SLIT1,MTR,PALLD,ZCCHC24,LMO3,DCAF5,PHLDB1,NHLH1,CAMTA1,PTBP2,NUMA1,GRIA2,GRIA4,GRID1,RFFL,TMEM257,KCNK10,PCDH8,PCDH9,ARHGAP19,PDE4B,TUB,GDAP1L1,CADM1,NEGR1,TJP2,PRRX1,PNKD,PKN2,CTNND1,EDRF1,PMEPA1,PRDM2,BLOC1S6,KCNA1,PTPRD,KCNA6,PTPRZ1,KCNK2,KIF2A,WIPF2,RALGDS,ZYG11B,RBM12" MicroRNA hsa-miR-3126-5p:mirSVR_highEffct hsa-miR-3126-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.21E-24 1.20E-20 1.24E-23 1.14E-22 48 570 "MAP6,SYT9,SORCS1,TRIM46,SFPQ,BCAN,SLC2A5,BCO1,SLC8A3,SCMH1,NAXD,AHCYL1,IDI2-AS1,NELL1,SEPT3,VAMP1,CASTOR3,ZNF638,VWC2,LRIT2,ZEB1,EML4,NUMA1,GRIA4,SEZ6L,TPM3,PRMT8,NRXN2,NMT2,FTO,FAM181B,C11orf49,BTF3L4,ACBD5,MFSD4A,FMN2,PSMD13,MAGI2,SV2A,NTM,KCNMA1,DLG2,DLG3,RAB5B,C12orf4,DTNA,SLC4A10,SEZ6" MicroRNA hsa-miR-1258:mirSVR_lowEffct hsa-miR-1258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.22E-24 1.20E-20 1.24E-23 1.14E-22 71 1285 "EPS8,ACLY,ATAT1,NDRG2,RTN1,GALNT13,WAC,FOXRED2,SLC44A5,SCN3A,MOBP,TRIM46,USP28,GPAM,SLITRK3,BCAS1,ARHGAP5,SLC14A1,DACH2,CADPS,SPHKAP,BRINP2,TMEM108,ATM,ARPP21,EMC1,NCAM1,CLASP2,ALDH1L1,GLS,SEMA4A,MYRF,GPM6B,ATF7,CACNA1E,ZEB1,VSTM2A,GRIK2,CRB1,INA,CDH8,TPM3,PCSK2,BEST3,HMGB1,TUB,PIK3CD,CNTN1,MFSD4A,RNF14,PPP3CB,NKAIN4,PRKACB,EDRF1,ZBTB16,WBP1L,RIMS3,CEP170,KCNH1,SRGAP3,DLG2,DLG3,WIPF2,SLC17A6,RASGRF1,DBX2,DTNA,ABCC9,CAMK1G,ATL1,UEVLD" MicroRNA hsa-miR-92a:mirSVR_highEffct hsa-miR-92a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.50E-24 1.36E-20 1.40E-23 1.29E-22 60 921 "TMEM74,CSMD2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FHL1,ANK3,USP28,SESN3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,B3GALT2,KIF1B,NPAS3,RGL1,PCDH11X,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,CAMK2A,VSTM2A,GRIA1,RFFL,AIFM1,CDH10,TPM4,PDE1A,SCRG1,CCSER2,CNRIP1,KCNT2,ATRNL1,VCAN,RBPJ,FMN2,USP54,EDRF1,ITGAV,LRP8,PTPRD,PLPPR4,PTPRO,KCNK1,PEX5,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65" MicroRNA hsa-miR-4257:mirSVR_highEffct hsa-miR-4257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.64E-24 1.43E-20 1.48E-23 1.36E-22 56 799 "ATAT1,MDM4,ADD3,UNC79,C1orf61,DOCK10,STK32C,PAAF1,MIER1,URGCP,RUFY2,ASCL1,ADGRA1,FYN,WDTC1,ILDR2,NEK6,CLASP2,LUZP2,GPM6A,CACNB2,BRSK2,GRIA1,GRIA4,CCKBR,TJP1,TMEM257,CDC42,TPM3,PCSK2,FNDC5,GDAP1L1,OPALIN,MFSD4A,RNF14,PPP3CB,PHACTR3,PRKACB,DZIP3,PLD5,MASP1,SYNC,ITGAV,PRDM2,MED24,ZC3H11A,PLPPR4,RAB5B,SLC25A48,L1CAM,ABCC9,USH1C,ATL1,ZNF248,RAVER2,SEZ6" MicroRNA hsa-miR-624*:mirSVR_lowEffct hsa-miR-624*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.78E-24 1.50E-20 1.55E-23 1.42E-22 70 1255 "ZFYVE27,KLHL32,RTN1,ADCY2,SLC44A5,FCGR1A,SCN3A,SLC30A10,ANK2,APBB1,ZNF365,MIER1,PKNOX2,SHANK2,NSG2,DACH2,CADPS,CGREF1,RCOR3,EIF4G3,NMNAT2,C11orf87,ERBIN,DCAF5,SEPT3,C1QC,CAMTA1,UNC5D,KLHL4,TCF12,PCDHGA3,GRIA2,GRIA4,CRB1,TMEM257,CDC42,PCDH9,PDE3B,ZMYND8,FNDC5,BEST3,SEMA5B,NMT2,FTO,BTF3L4,PRRX1,FAT3,CRLS1,PPP2R5C,PPP3CB,KCNT2,ATRNL1,RIMS4,USP54,TOMM20,RGMA,CEP170,BLOC1S6,KCNA4,KCNA6,PLPPR4,DLG2,PLEKHB2,FAM13C,ABCC9,ZYG11B,ATL1,RNF220,RBM12,ABI2" MicroRNA hsa-miR-20b*:mirSVR_highEffct hsa-miR-20b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-24 1.73E-20 1.78E-23 1.63E-22 58 863 "SYT9,MDM4,CSMD3,F3,SCN3A,KIAA1109,CDC42BPA,ANK3,APC,NTNG1,API5,SHTN1,MIER1,ASPH,RCOR3,PHYHIPL,TNIK,ARPP21,NPAS3,ADHFE1,ARHGEF7,GLS,PCDH11X,ZNF638,ANO4,GPM6A,CACNB2,GRIA4,GRID1,CRB1,TGFBR3,TJP1,MAEL,HPS5,PDE4B,HMGB1,TMEFF2,PRRX1,NXPH1,CHD1L,RNF14,ATRNL1,NRSN1,MAPK10,PTAFR,DNAJC6,ITGAV,COPS7A,KCNA2,PTPRZ1,ARNT2,PCDH15,FAM13C,ATL1,PHC2,RNF220,RPRD1A,VWA5A" MicroRNA hsa-miR-4266:mirSVR_lowEffct hsa-miR-4266:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.20E-24 1.73E-20 1.78E-23 1.63E-22 74 1400 "ASIC1,MAPT,MEG3,KCNIP2,FABP7,CHST15,GPR158,MOBP,SELL,BCAN,RPH3A,ASPH,SORCS3,KBTBD12,SNAP25,KIF21B,ARPP21,CLASP2,STOX1,KIRREL3,FAM168A,MLC1,PSRC1,ADGRL3,TMEM136,LRIT2,NEU4,PCDHGA3,VSTM2A,GRIA1,RFFL,GRIK2,GPR88,SHISA7,USP2,CELF3,MAEL,TNR,CDH8,LGI1,TPD52,LINC01102,GPR37L1,BEST3,TMPRSS5,PFKFB3,CASC2,CAMKV,ANLN,CCSER2,BTF3L4,CNRIP1,MFSD4A,PNKD,KIAA1755,PLPP4,PUM1,PROX1,KIAA0408,WBP1L,SYNC,BDNF-AS,MAGI2,SRGAP3,PYGM,RAP1GAP,ABI1,NUP214,RET,RPRD1A,ABI2,RAVER2,RCAN2,BAALC" MicroRNA hsa-miR-3196:mirSVR_lowEffct hsa-miR-3196:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.25E-24 1.76E-20 1.81E-23 1.66E-22 49 602 "DPF1,RTN3,SYNDIG1,EXTL1,FAM43B,ATAT1,FOXRED2,SEMA6C,ITSN1,DGKZ,MADD,SLC6A9,ATP1A3,SOX10,FXYD6,C11orf87,ALDH1L1,NCDN,SLCO1C1,TBX15,ATF7,NEU4,NRGN,BRSK2,GRIN1,FBXL16,TMEM9,IGSF21,HPSE2,PFKFB3,JAM2,HPCA,NLGN3,CCSER2,FADS2,PLCH2,FMN2,SIRPA,PRDM2,SMG7,AK5,KLRC3,SUSD4,L1CAM,ARHGEF10L,EEF1A2,CACNG7,EFNA3,OLIG2" MicroRNA hsa-miR-199a-3p:mirSVR_highEffct hsa-miR-199a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.34E-24 1.81E-20 1.86E-23 1.70E-22 61 958 "ARID1A,RTKN,MDM4,ADD3,SLC44A5,TESK2,LRRTM4,LINC00461,BCAR3,ELMOD1,MOBP,MOG,ERICH3,ANK2,CNIH2,NTNG1,MAGI3,ZCCHC17,TACC2,SLC8A3,CCDC88A,CADPS,ASTN1,ATM,PHYHIPL,DKK3,USP33,EMC1,LMO3,CLASP2,PCDH11X,ZNF638,KAZN,GPM6B,CACNB2,EML4,TMEM25,MAEL,DCLK1,PDE4B,ANO5,MS4A7,SERPINE2,SLC25A27,NXPH1,RNF14,OSBPL3,USP54,FGFR1OP2,SYTL2,SPIRE1,BDNF-AS,PTPRE,PTPRZ1,DLG2,KIF2A,DTNA,RTN4,ATL1,SH3GLB1,EPB41L2" MicroRNA hsa-miR-199b-3p:mirSVR_highEffct hsa-miR-199b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.34E-24 1.81E-20 1.86E-23 1.70E-22 61 958 "ARID1A,RTKN,MDM4,ADD3,SLC44A5,TESK2,LRRTM4,LINC00461,BCAR3,ELMOD1,MOBP,MOG,ERICH3,ANK2,CNIH2,NTNG1,MAGI3,ZCCHC17,TACC2,SLC8A3,CCDC88A,CADPS,ASTN1,ATM,PHYHIPL,DKK3,USP33,EMC1,LMO3,CLASP2,PCDH11X,ZNF638,KAZN,GPM6B,CACNB2,EML4,TMEM25,MAEL,DCLK1,PDE4B,ANO5,MS4A7,SERPINE2,SLC25A27,NXPH1,RNF14,OSBPL3,USP54,FGFR1OP2,SYTL2,SPIRE1,BDNF-AS,PTPRE,PTPRZ1,DLG2,KIF2A,DTNA,RTN4,ATL1,SH3GLB1,EPB41L2" MicroRNA hsa-miR-548p:PITA hsa-miR-548p:PITA_TOP PITA 3.37E-24 1.83E-20 1.87E-23 1.72E-22 59 895 "EPS8,ADD3,SCN3A,LRRTM4,SOX6,ANK3,APC,MAGI3,GAS7,API5,CADPS,ATP1A2,PALLD,SOX1,MYT1L,KIF21B,NCAM1,LMO3,CLASP2,ERBIN,NFIA,CAMTA1,BTRC,GPM6A,PTBP2,CAMK2A,CAMK2G,PSD3,GRIA2,GRIA4,TMEM25,ZFP91,MAGI1,HMGB1,CAMKV,ANLN,NSD2,KCNT2,OSBPL3,ATRNL1,NCAN,RBPJ,PKN2,TOX,CSDE1,ZC3H11A,OLFM3,KCNA6,DLG2,SLC17A6,GOPC,PAK5,SLC6A15,ST8SIA3,TTLL7,VANGL2,GPR61,ELAVL3,EPB41L2" MicroRNA hsa-miR-433:mirSVR_highEffct hsa-miR-433:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.45E-24 1.87E-20 1.91E-23 1.75E-22 64 1056 "RABEPK,ACER3,CSMD3,CLIP1,KLHL32,DSCAML1,ADD3,BCAR3,SELL,USP28,SESN3,MAGI3,MIER1,MSR1,ASPH,TMEM108,B3GALT2,EMC1,SALL3,TTLL9,KIF1B,ZNF302,C1QC,CAMTA1,ADGRL3,ZEB1,EML4,GRIA2,TJP1,REPS2,LGI1,PRMT8,ZMYND8,MS4A7,NRXN1,NMT2,SLC36A4,NXPH1,CNRIP1,CP,MED1,PPP3CB,FEZ2,PRKACB,NRSN1,DNAJC6,ITGAV,PTHLH,HP1BP3,CEP170,STMN4,PCDH15,KCNMA1,CAB39L,KIF2A,TMEM255A,PARP11,ABI1,ABCC9,RET,SEC61A2,SSPN,RBM12,VWA5A" MicroRNA hsa-miR-92a-2*:mirSVR_highEffct hsa-miR-92a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.79E-24 2.05E-20 2.10E-23 1.93E-22 56 805 "RABEPK,ZFYVE27,EYA1,FOXRED2,FGR,SELL,ERICH3,PI16,ITSN1,SH3GL2,SNCB,ATP1A2,ATP2B2,WDTC1,MYT1L,ZSWIM8,B4GALNT1,HEPN1,SEPT3,ARHGEF7,C1QC,GNAS,CAMTA1,DIRAS1,NRGN,INA,TPM4,PDE2A,PRMT8,SLC22A6,FADS2,CNTN1,COL9A2,ACBD5,CP,POU3F2,RBPJ,PKN2,USP54,IGSF1,PUM1,KLK6,ANKS1B,PRTFDC1,KCNA2,KCNJ10,HS3ST4,DPP6,L1CAM,ABCC9,USH1C,INSYN2,PHC2,SEC61A2,EFNA3,OLIG2" MicroRNA hsa-miR-302d*:mirSVR_highEffct hsa-miR-302d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.89E-24 2.11E-20 2.15E-23 1.98E-22 72 1333 "MDM4,KLHL32,SLITRK1,GALNT13,ERMN,SCN3A,LRRC7,FGF14,SFPQ,CDC42BPA,ANK1,ANK2,USP28,PPFIA1,PKP4,DOCK10,SESN3,MAGI3,CCDC80,BCAS1,SHANK2,DACH2,SLIT1,ATP1A2,NRG3,SON,EMC1,SALL3,NCAM1,NDUFA5,ZNF638,DDHD2,NODAL,LRIT2,PTBP2,EML4,GRIA2,TLL2,ATG4C,PAX6,REPS2,TNS1,PCDH9,CIART,ANLN,SLC25A27,PRRX1,P2RY12,CNRIP1,CP,POU3F2,CHD1L,PPP2R5C,SNCAIP,OSBPL3,CTNND2,PROX1,FGFR1OP2,DNAJC6,PLPPR4,KCNC1,KCNK2,PCDH15,KCNMA1,DLG2,DSCAM,ABCC9,JMJD1C,RGS7,CBLN2,RAVER2,EN2" MicroRNA hsa-miR-450b-3p:mirSVR_lowEffct hsa-miR-450b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.07E-24 2.20E-20 2.25E-23 2.06E-22 72 1334 "ABAT,C1orf194,SYNDIG1,MEG3,ATAT1,GALNT13,SORCS1,ADORA1,LRRTM4,FGF1,HPCAL4,ERICH3,CDC42BPA,BCAN,CACHD1,NLGN1,SLC8A3,DACH2,TMEM249,SPHKAP,ASTN1,B3GAT1,TMEM108,MEGF11,USP33,ZSWIM8,ARPP21,STARD10,FXYD6,NCAM1,COLGALT2,SMOC1,SEPT3,ARHGEF7,CASTOR3,ZNF638,NHLH1,CAMTA1,PCDHGA3,OPCML,MAGI1,PDYN,ZBED5,DLGAP3,GDAP1L1,MEAF6,BEST1,COL9A2,NSD2,MFSD4A,SF1,NCAN,PRKAB2,FMN2,ZBTB16,DPYSL5,TOMM20,MAGI2,OLFM3,OCIAD1,KCNK2,DLG2,CAB39L,KIF2A,C12orf4,CRTAC1,RGS7,ZNF248,VANGL2,RERGL,VWA5A,FGFBP3" MicroRNA hsa-miR-3159:mirSVR_lowEffct hsa-miR-3159:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.24E-24 2.30E-20 2.34E-23 2.15E-22 75 1443 "ACER3,LGR4,SYNDIG1,ACTN2,MDM4,CSMD3,ADARB2,ADORA3,TOMM40L,KIAA1109,ERICH3,USP28,PPFIA1,ANXA7,ZNF365,RUFY2,LRRC55,SLC6A9,SCG3,ASTN1,NRG3,FYN,SCN3B,EMC1,NPAS3,RGL1,SEPT3,SYT4,LUZP2,NKX2-2,CAMTA1,WWC1,KLHL4,VWC2,AZIN2,GRIA4,GRIK4,CRB1,PAX6,TPM3,ZMYND8,JAM2,KIAA1549L,CCSER2,SPATA6,ATCAY,ACBD5,MED1,SF1,SNCAIP,PPP3CB,NCAN,RBPJ,ARHGEF4,KIAA0408,TOMM20,PLPPR5,PTCH1,ITGAV,PTHLH,CSDE1,OLFM3,SV2A,RABGAP1L,PCDH15,DLG2,PLEKHB2,RASGRF1,GNE,CAMK1G,RERGL,ARHGAP12,C2orf80,PRRT4,EPB41L2" MicroRNA hsa-miR-409-3p:mirSVR_highEffct hsa-miR-409-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.96E-24 2.69E-20 2.74E-23 2.51E-22 69 1233 "PRR5L,CSMD3,KLHL32,ANK3,API5,DACH2,SMARCE1,RCOR3,ADGRA1,TNIK,SOX5,ILDR2,GAD2,AHCYL1,SALL3,NPAS3,NCAM1,LMO3,ERBIN,RCOR2,RGL1,NKX2-2,CAMSAP2,UNC5D,MMD2,GPM6A,ZEB1,PTBP2,NUDT21,EML4,VXN,GRIA4,GRIK2,OLR1,AIFM1,LGI1,TPM3,MAGI1,HMGB1,HNRNPK,NXPH1,MFSD4A,ATRNL1,PLCH2,VCAN,PHACTR3,RAB39A,PKN2,PLD5,PUM1,TOX,BDNF-AS,CEP170,MAGI2,OCIAD1,PTPRD,KCNC1,PTPRZ1,KCNJ10,KCNK2,SLC17A6,ABI1,GNE,FAM13C,ABCC9,SEC61A2,SSPN,CBLN2,YY1AP1" MicroRNA hsa-miR-517*:mirSVR_lowEffct hsa-miR-517*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-24 2.71E-20 2.75E-23 2.53E-22 75 1447 "EPS8,ACER3,MBP,MRVI1,CSMD3,CLIP1,ADCY2,GALNT13,TOMM40L,FGF1,PLA2G6,FHL1,SOX6,CDC42BPA,ANXA7,APBB1,GPAM,SLITRK3,SORBS1,NLGN1,CCDC88A,ASPH,ASTN1,WDTC1,TNIK,SOX5,CADM3,GAD2,AHCYL1,ENKUR,NFASC,COLGALT2,BCL2L2,DCAF5,KIRREL3,SLCO1C1,GLS,CASTOR3,PCDH11X,CAMSAP2,ADGRL3,KLHL4,TCF12,SHISA7,OPCML,TGFBR3,PAX6,CDC42,FNDC5,JAM2,CCSER2,SLC25A27,NSD2,MICAL2,ATRNL1,FMN2,TOX,ANKS1B,PHYHIP,PLPPR5,SYNC,PLPPR1,PRDM2,PLPPR4,SNX27,WIPF2,PLEKHB2,RASGRF1,PAK5,SLC6A15,ZYG11B,TTLL7,RPRD1A,ABI2,ARHGAP12" MicroRNA hsa-miR-623:mirSVR_highEffct hsa-miR-623:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.10E-24 2.76E-20 2.81E-23 2.57E-22 53 721 "SYT9,RTN3,MDM4,NDRG2,TMEM156,SLC44A5,CHST15,TOMM40L,GPR158,PPFIA1,BCAN,TACC2,NLGN1,ST3GAL3,USP16,ZNF365,YPEL4,SMARCE1,ATM,ILDR2,TTLL9,NASP,GANAB,GLS,CAMSAP2,CACNB2,GPR19,TCF12,CRB1,DCLK1,LGI1,ZNF384,CASC2,JAM2,ZFYVE9,PIK3CD,SNCAIP,KCNT2,PHACTR3,PRKACB,DOCK7,PLPP4,MAPK10,SYTL2,LRRTM3,PSMD13,ITGAV,PTHLH,PTPRD,NTM,PID1,RGS10,ARHGAP12" MicroRNA hsa-miR-885-5p:mirSVR_highEffct hsa-miR-885-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.18E-24 2.80E-20 2.85E-23 2.61E-22 50 636 "TMEM74,RTN3,EYA1,MDM4,AMER2,TOMM40L,SCN3A,LRRTM4,KIAA1109,SEMA6A,ERICH3,SGIP1,FOLH1,USP28,SH3GL2,NTNG1,JAKMIP3,API5,SHTN1,SMARCE1,ENKUR,ARPP21,ERBIN,NEUROD1,GLS,PTBP2,NUDT21,EML4,ZFP91,CDC42,PCDH9,HNRNPK,TMEFF2,JAM2,KIAA1549L,VCAN,PHACTR3,NRSN1,TOX,TUBB2B,DLG2,KIF2A,HS3ST4,ABI1,GOPC,PAK5,RET,LMO1,CBLN2,ELAVL4" MicroRNA hsa-miR-1912:mirSVR_highEffct hsa-miR-1912:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.34E-24 2.89E-20 2.94E-23 2.69E-22 54 751 "PRR5L,ACER3,ARID1A,SLITRK1,ADD3,LRRTM4,ACTL6B,MOBP,CNIH2,ITSN1,SYBU,BCAS1,USP16,PKNOX2,SON,SOX1,SOX5,NPAS3,GANAB,CAMSAP2,ZEB1,GRIK2,AIFM1,TLL2,CDH8,HRH3,SEZ6L,TPM3,NLGN3,A2ML1,IFFO1,MFSD4A,MED1,RNF14,PPP3CB,EDRF1,FGFR1OP2,GON4L,TOMM20,PSMD13,SIRPA,CSDE1,SMG7,NTM,KCNN3,CAB39L,DNAH9,GOPC,SLC6A15,RET,SYT15,SLC4A10,OLIG2,EPB41L1" MicroRNA hsa-miR-3161:mirSVR_highEffct hsa-miR-3161:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.60E-24 3.03E-20 3.07E-23 2.82E-22 57 842 "ATAT1,CSMD3,CLIP1,RTN1,ADORA3,LRRTM4,ITSN1,SLITRK3,SHTN1,ZNF365,MIER1,SPHKAP,ASPH,PHYHIPL,SOX5,CAB39,NEK6,LMO3,NDUFA5,NELL1,ZNF638,GOLGB1,ZEB1,GRIA1,GPR88,OPCML,CRB1,AIFM1,ZFP91,TNFRSF1B,LGI1,PCSK2,LINC01102,HMGB1,ANO5,MS4A7,CADM1,NRXN1,SPATA6,CNRIP1,PNKD,RNF14,CRLS1,DZIP3,MASP1,SYNC,PTCH1,PTHLH,PTPRE,PTPRO,KCNMA1,DNAH9,DBX2,RET,RBM12,VWA5A,EN2" MicroRNA hsa-miR-1193:mirSVR_lowEffct hsa-miR-1193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.23E-24 3.37E-20 3.41E-23 3.13E-22 69 1238 "LOC100128239,ASIC1,ADGRV1,CSMD2,KLRC4,GALNT13,FOXRED2,TOMM40L,SELL,PI16,APC,GPAM,BCAS1,MSR1,RCOR3,PHYHIPL,WDTC1,SOX10,KIF1B,NFASC,NCAM1,DCAF5,RGL1,FAM168A,NFIA,PCDH11X,OS9,LUZP2,CNDP1,PTBP2,NUDT21,PCDHGA3,OPCML,PCDH9,SEZ6L,LGI1,ASIC3,CASC2,HERC2P3,GDAP1L1,NEGR1,BEST1,PNKD,SNCAIP,TENM4,OSBPL3,PRKCG,PRKCZ,CTNND2,NRSN1,TOX,TOMM20,PTAFR,STMN4,OCIAD1,KCNA6,PTPRE,PLPPR4,ARNT2,FAM66C,DPP6,RALGDS,SLC25A18,CRTAC1,RFX4,CACNG7,RPRD1A,ABI2,ELAVL3" MicroRNA hsa-miR-519d-3p:TargetScan hsa-miR-519d-3p TargetScan 6.68E-24 3.62E-20 3.66E-23 3.35E-22 61 971 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,OPCML,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-605:mirSVR_highEffct hsa-miR-605:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.80E-24 3.68E-20 3.72E-23 3.41E-22 65 1103 "ACER3,WLS,F3,SLITRK1,ADD3,FABP7,FCGR1A,CHST15,LINC00461,FGF14,ASIC4,SLC30A10,SOX6,ANXA7,GPAM,ST3GAL3,CCDC88A,PALLD,DKK3,MYT1L,TTLL9,NEUROD1,ARHGEF7,GLS,PCDH11X,OS9,DDHD2,CAMSAP2,ADGRL3,TMEM136,GPM6B,PRLHR,CECR2,VXN,GRIA2,MAEL,CDC42,TPM4,MAGI1,PDE3B,CASC2,ZBED5,HNRNPK,MED1,MICAL2,RBPJ,USP54,MASP1,SYTL2,PTCH1,PRDM2,PRTFDC1,KCNA2,KCNC1,KCNK2,PCDH15,CAB39L,DPP6,FAM13C,DTNA,JMJD1C,SFXN5,SLC4A10,ELAVL4,EPB41L1" MicroRNA hsa-miR-520a-3p:mirSVR_highEffct hsa-miR-520a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.13E-24 3.86E-20 3.90E-23 3.58E-22 69 1241 "EPS8,LGR4,MDM4,AMER2,GPR158,ANK2,MAGI3,SLITRK3,TACC2,API5,CLSTN1,USP16,SLC1A6,YPEL4,SLC14A1,RCOR3,MEGF11,MYT1L,TNIK,ARPP21,LMO3,DCAF5,RGL1,NEUROD1,ZNF638,CAMTA1,CAMSAP2,UNC5D,ADGRL3,GPM6A,ZEB1,SYT6,NUMA1,GRIA1,CRB1,TMEM25,LEFTY2,AIFM1,HPS5,TNS1,C1orf94,PCDH9,MAGI1,PRRX1,SPATA6,ACBD5,CNRIP1,MED1,PPP3CB,FEZ2,PRKACB,PKN2,IGSF1,MASP1,TOX,SYNC,PTHLH,CADM2,HP1BP3,RGMA,BLOC1S6,ZC3H11A,OLFM3,KCNMA1,HS3ST4,FAM13C,PAK5,SLC6A15,TMEM100" MicroRNA hsa-miR-2114*:mirSVR_lowEffct hsa-miR-2114*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.33E-24 3.97E-20 4.00E-23 3.67E-22 71 1312 "ABAT,FAM43B,WAC,PNMA8B,CHST15,HPCAL4,SOX6,CNIH2,MIER1,MSR1,CGREF1,SLIT1,ARFGAP1,ALDH4A1,ATM,ATP2B2,DKK3,WDTC1,B3GALT2,ZSWIM8,AHCYL1,ARPP21,TTLL9,KIF1B,NFASC,NCAM1,PHLDB1,RHBDL3,ZNF638,DCLK2,GNAS,NODAL,MMD2,CNTN2,NPPA,ZEB1,GPR17,HAP1,PTBP2,ZFP91,KCNK10,TNFRSF1B,CDC42,PCDH9,LGI1,PIRT,FNDC5,TMPRSS5,LRTM2,PRRX1,NSD2,MFSD4A,PPP2R5C,PRKCG,PRKCZ,PLPPR5,BDNF-AS,C1orf109,SV2A,DLG3,HS3ST4,WIPF2,DNM2,RAD52,RASGRF1,FAM13C,ABCC9,SLC6A15,CRTAC1,ARHGEF10L,PHC2" MicroRNA hsa-miR-940:PITA hsa-miR-940:PITA_TOP PITA 7.39E-24 4.00E-20 4.03E-23 3.70E-22 35 278 "SDE2,ELMOD1,HPCAL4,MOBP,ANK1,CCDC80,SORCS3,RCOR3,EIF4G3,KIF21B,NMNAT2,JPH4,CPLX2,FAM168A,VAMP1,ASTN2,CAMSAP2,PSD3,TPM3,PDE2A,TUB,DLGAP3,NRXN2,POU3F2,MED1,PNKD,MAPK10,CADM2,KCNA1,SRGAP3,KCNMA1,DLG2,ST8SIA3,VANGL2,RASGRP2" MicroRNA "CAGTATT,MIR-200B:MSigDB" "CAGTATT,MIR-200B:MSigDB" MSigDB 8.24E-24 4.46E-20 4.48E-23 4.11E-22 42 434 "EPS8,CSMD3,ADCY2,SLITRK1,FHL1,FOXG1,SGIP1,ANK3,PPM1E,JAKMIP3,SLC1A2,SLC14A1,SNAP25,SCN3B,SOX1,ZCCHC24,CAB39,ARPP21,CLASP2,RGL1,PHLDB1,NFIA,MMD2,GPM6A,PCDH8,HNRNPK,TMEFF2,NEGR1,ANLN,BTF3L4,NXPH1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,WBP1L,LRRTM3,PTHLH,PTPRZ1,KCNK2,PAK5" MicroRNA "CAGTATT,MIR-200C:MSigDB" "CAGTATT,MIR-200C:MSigDB" MSigDB 8.24E-24 4.46E-20 4.48E-23 4.11E-22 42 434 "EPS8,CSMD3,ADCY2,SLITRK1,FHL1,FOXG1,SGIP1,ANK3,PPM1E,JAKMIP3,SLC1A2,SLC14A1,SNAP25,SCN3B,SOX1,ZCCHC24,CAB39,ARPP21,CLASP2,RGL1,PHLDB1,NFIA,MMD2,GPM6A,PCDH8,HNRNPK,TMEFF2,NEGR1,ANLN,BTF3L4,NXPH1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,WBP1L,LRRTM3,PTHLH,PTPRZ1,KCNK2,PAK5" MicroRNA "CAGTATT,MIR-429:MSigDB" "CAGTATT,MIR-429:MSigDB" MSigDB 8.24E-24 4.46E-20 4.48E-23 4.11E-22 42 434 "EPS8,CSMD3,ADCY2,SLITRK1,FHL1,FOXG1,SGIP1,ANK3,PPM1E,JAKMIP3,SLC1A2,SLC14A1,SNAP25,SCN3B,SOX1,ZCCHC24,CAB39,ARPP21,CLASP2,RGL1,PHLDB1,NFIA,MMD2,GPM6A,PCDH8,HNRNPK,TMEFF2,NEGR1,ANLN,BTF3L4,NXPH1,PPP2R5C,FEZ2,PHACTR3,PRKACB,CTNND2,WBP1L,LRRTM3,PTHLH,PTPRZ1,KCNK2,PAK5" MicroRNA hsa-miR-4260:mirSVR_highEffct hsa-miR-4260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.98E-24 4.86E-20 4.88E-23 4.47E-22 47 562 "MAG,SYT9,RXRG,TESK2,CNIH2,PPFIA1,SORBS1,ZNF365,SFMBT2,MSR1,ARFGAP2,ATP1A3,MEGF11,STARD10,ALDH1L1,SEPT3,NKX2-2,MYRF,TGFBR3,USP2,INA,PCSK2,ZNF384,CHRM1,JAM2,GDAP1L1,SEMA5B,BEST1,P2RY12,CSF3R,ATRNL1,VCAN,DOCK7,CTNND1,GON4L,ZC3H11A,PTPRZ1,KCNJ9,KCNJ10,NKAIN1,RAB3IL1,SLC25A48,DPP6,SUSD4,GNE,RCAN2,LRRC23" MicroRNA hsa-miR-155*:mirSVR_highEffct hsa-miR-155*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.78E-24 5.29E-20 5.31E-23 4.87E-22 69 1248 "CSMD2,F3,SLITRK1,FABP7,FOXRED2,FCGR1A,FHL1,FOXG1,ANK2,USP28,ITSN1,SLITRK3,CCDC88A,DACH2,SLN,BRINP2,NRG3,PALLD,USP33,B4GALNT1,NEK6,LMO3,NDUFA5,ZNF302,ADHFE1,SEPT3,ZNF638,DDHD2,ADGRL3,GPM6A,CACNA1E,GPR17,PTBP2,GRIA2,CRB1,INA,MAEL,CDH8,CDH10,RBFOX2,ADGRG1,ANO5,HNRNPK,TMEFF2,CADM1,UBTF,SULT4A1,NXPH1,MED1,FEZ1,ATRNL1,USP54,CTNND1,ZNF385B,DNAJC6,ITGAV,MAGI2,ZC3H11A,KCNK1,PCDH15,PEX5,GOPC,FAM13C,RTN4,PAK5,ABCC9,RFX4,VANGL2,GPR61" MicroRNA hsa-miR-222:mirSVR_highEffct hsa-miR-222:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.04E-23 5.62E-20 5.63E-23 5.16E-22 56 822 "ARID1A,CSMD3,KLHL32,ERMN,PPFIA1,SYBU,CCDC88A,SHANK2,CAPRIN2,ASPH,SON,SOX10,NAP1L2,SPART,C11orf87,CLASP2,ZNF302,ADHFE1,GLS,LUZP2,DDHD2,CAMTA1,UNC5D,GPM6A,TCF12,DIRAS1,GRIA4,GPR88,CYB561A3,INA,MAGI1,PDE4B,FNDC5,CADM1,A2ML1,NXPH1,MED1,CRLS1,PPP3CB,RGS6,PLD5,MAPK10,BRINP3,TOX,DNAJC6,PLPPR1,PRDM2,KCNA1,KCNK2,SLC17A6,PAK5,ABCC9,ZYG11B,SEC61A2,SLC4A10,BAALC" MicroRNA hsa-miR-188-5p:mirSVR_highEffct hsa-miR-188-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-23 5.74E-20 5.74E-23 5.26E-22 55 792 "RABEPK,CNTNAP3,ATAT1,GPR158,KIAA1109,FGF14,USP28,DOCK10,CCDC80,API5,SLC8A3,CCDC88A,MYT1L,B3GALT2,ARPP21,NEK6,TTLL9,NPAS3,ALDH1L1,GANAB,ARHGEF7,GLS,ZNF638,CAMTA1,GOLGB1,PTBP2,VXN,GRIA2,LINC00839,CRB1,TIE1,ZFP91,PCDH9,MAGI1,PDE3B,C11orf49,MEAF6,RNF14,FEZ1,PRKAB2,PTAFR,ITGAV,PRDM2,PTPRD,NTM,RABGAP1L,KCNK2,PCDH15,DLG3,PARP11,ABI1,FAM13C,RGS10,SEC61A2,ELAVL4" MicroRNA hsa-miR-513c:mirSVR_highEffct hsa-miR-513c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-23 5.99E-20 5.98E-23 5.49E-22 66 1147 "SDE2,ADGRV1,ATAT1,MDM4,F3,SLITRK1,WAC,GPR158,FGF1,FOXG1,SLITRK3,RUFY2,CCDC88A,ASPH,SMARCE1,ATM,NRG3,EIF4G3,MEGF11,CAB39,DCAF5,GLS,VAMP1,DCLK2,DDHD2,ADGRL3,KLHL4,GPM6B,VXN,GRIA4,LEFTY2,RBFOX2,SEZ6L,ZNF384,PDE3B,GPR37L1,CHGA,CADM1,CCSER2,BTF3L4,PMS2,SLC36A4,RNF14,PPP2R5C,FEZ2,DOCK7,PLPP4,MAPK10,NOS1AP,FGFR1OP2,MASP1,SYTL2,ANKS1B,ITGAV,HP1BP3,NTM,KCNK1,DLG2,PID1,SLC6A15,ZYG11B,RET,JMJD1C,SEC61A2,ELAVL3,UEVLD" MicroRNA hsa-miR-485-5p:mirSVR_highEffct hsa-miR-485-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.18E-23 6.40E-20 6.38E-23 5.85E-22 57 855 "SYT9,LDLRAD3,FABP7,LRRTM4,LRRC7,ASIC4,BCAR3,ST3GAL3,MSRA,PDE8B,ASPH,RCOR3,ATP2B2,SOX5,ZSWIM8,SPART,ANO4,CACNB2,TMEM151B,GRIK3,GPR88,CRB1,USP2,TIE1,LGI1,ZNF384,TLX1,SERPINE2,OPALIN,CCDC136,PRRX1,MFSD4A,CHD1L,MED1,PNKD,SF1,FEZ1,MICAL2,PRKACB,PRKCG,PLPP4,PLPPR1,CADM2,PTPRE,NTM,KCNK2,PEX5,PARP11,DTNA,SLC6A15,FAM135B,ARHGEF10L,PHC2,RPRD1A,RAVER2,SLC4A10,EPB41L2" MicroRNA hsa-miR-380*:mirSVR_lowEffct hsa-miR-380*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-23 6.40E-20 6.38E-23 5.85E-22 57 855 "ABAT,ADGRV1,WLS,RTKN,GRAMD1B,BBOX1,SLC30A10,SOX6,ANXA7,NTNG1,SHTN1,SLC2A5,MSR1,SLN,TMEM108,NFASC,NDUFA5,PHLDB1,NEUROD1,ZNF638,LUZP2,CAMSAP2,UNC5D,BTRC,KLHL4,PTBP2,VXN,BRSK2,GRIA1,LINC00839,CRB1,TIE1,TLL2,TMEM257,PCDH9,CDH8,ZFYVE9,TJP2,MEAF6,VCAN,RBPJ,PRKCZ,IGSF1,CTNND2,PUM1,ZBTB16,DPYSL5,GON4L,TOMM20,LRRTM3,JAKMIP2,OCIAD1,PTPRE,KCNMA1,DPP6,DTNA,TMEM100" MicroRNA hsa-miR-4272:mirSVR_highEffct hsa-miR-4272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-23 6.68E-20 6.65E-23 6.10E-22 71 1324 "TMEM74,ACTN2,CLIP1,GALNT13,WAC,FABP7,ADORA3,FGF14,FHL1,ELMOD1,SGIP1,FOLH1,USP28,DOCK10,APC,MAGI3,GPAM,SORBS1,SHTN1,MSR1,SLC8A3,SLC14A1,ASPH,SORCS3,USP33,DNER,NCAM1,LMO3,PCDH11X,SYT4,DDHD2,ADGRL3,KLHL4,CACNA1A,GRIA2,GRIA4,GRIK2,OLR1,MAEL,HPS5,CDH8,PDE4B,PIRT,ADGRG1,CASC2,NEGR1,NMT2,FAAP20,NXPH1,MFSD4A,PNKD,PPP3CB,RBPJ,FMN2,IGSF1,EDRF1,TUBB2B,ZNF385B,CADM2,PRTFDC1,BLOC1S6,OCIAD1,PTPRE,PTPRO,RABGAP1L,DLG2,SLC17A6,RALGDS,SYT15,ELAVL4,EN2" MicroRNA hsa-miR-506:PITA hsa-miR-506:PITA_TOP PITA 1.26E-23 6.80E-20 6.76E-23 6.21E-22 52 706 "EPS8,ACHE,CLIP1,RYR1,SORCS1,SCN4B,SEMA6A,GPAM,SLITRK3,SLIT1,PALLD,ZCCHC24,LMO3,DCAF5,PHLDB1,NHLH1,CAMTA1,PTBP2,NUMA1,GRIA2,GRIA4,GRID1,RFFL,TMEM257,KCNK10,PCDH8,PCDH9,ARHGAP19,PDE4B,TUB,GDAP1L1,CADM1,NEGR1,TJP2,PRRX1,PNKD,PKN2,CTNND1,EDRF1,PMEPA1,PRDM2,BLOC1S6,KCNA1,PTPRD,KCNA6,PTPRZ1,KCNK2,KIF2A,WIPF2,RALGDS,ZYG11B,RBM12" MicroRNA hsa-miR-1269:mirSVR_lowEffct hsa-miR-1269:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-23 6.84E-20 6.80E-23 6.24E-22 70 1289 "SERPINA3,ASIC1,CNTNAP3,ADAR,SLC44A5,LINC00461,GOLGA7B,MOBP,FOXG1,SOX6,TRIM46,DOCK10,DGKZ,NLGN1,MIER1,LRRC55,SPHKAP,ASPH,SORCS3,ASTN1,RCOR3,B3GAT1,EIF4G3,PALLD,MEGF11,DKK3,SOX1,ZCCHC24,AHCYL1,NFASC,GPR162,GFAP,INKA2,CASTOR3,PCDH11X,ADGRL3,ANO4,EML4,VXN,GRIA1,GRM3,OPCML,CRB1,PADI2,DCLK1,RBFOX2,IGFN1,PDE4B,ZMYND8,GDAP1L1,KIAA1549L,MFSD4A,SF1,CRLS1,KCNT2,ATRNL1,PRKACB,DNAJC6,ITGAV,KCNA1,OLFM3,C1orf109,OLIG1,DPP6,DSCAM,DTNA,BSDC1,SYT15,EN2,SEZ6" MicroRNA hsa-miR-759:mirSVR_highEffct hsa-miR-759:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-23 7.48E-20 7.43E-23 6.82E-22 58 889 "RABEPK,SDE2,ACER3,LGR4,RTN3,CSMD3,SLITRK1,SORCS1,TOMM40L,UNC79,ELMOD1,MOG,ITSN1,APC,TACC2,NLGN1,BCAS1,STK32C,MIER1,RUFY2,CADPS,SLIT1,CAPRIN2,MTR,MYBPC1,ADGRB2,CLASP2,PCDH11X,ASTN2,KAZN,GNAS,ADGRL3,GPM6A,GPM6B,BRSK2,INA,HMGB1,HERC2P3,JAM2,NOMO2,SPATA6,P2RY12,NXPH1,PNKD,PPP2R5C,VCAN,MASP1,SYNC,PLPPR1,BDNF-AS,PRDM2,CEP170,PTPRE,PCDH15,DNM2,SLC25A18,ATL1,RPRD1A" MicroRNA hsa-miR-26a-2*:mirSVR_highEffct hsa-miR-26a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-23 8.44E-20 8.37E-23 7.68E-22 76 1512 "RABEPK,LOC100128239,SYT9,RTN3,EXTL1,ACTN2,MEG3,ADGRV1,MDM4,SLITRK1,ADD3,SORCS1,GRAMD1B,SCN3A,LRRC7,SLC30A10,USP28,ITSN1,NTNG1,MAGI3,SCG3,ASPH,SMARCE1,ATM,MYT1L,NAP1L2,NCAM1,LMO3,CLASP2,PCDH11X,ZNF638,CAMSAP2,TBX15,WSCD1,CACNA1E,PRLHR,ZEB1,NUDT21,GRIA4,OLR1,INA,DAAM2,TNS1,PCDH9,TPD52,BEST3,ANO5,GDAP1L1,FLRT1,PRRX1,SLC36A4,CHD1L,KCNT2,ATRNL1,DOCK7,DZIP3,USP54,CTNND1,CTNND2,ANKS1B,PLPPR5,BDNF-AS,BLOC1S6,OCIAD1,PCDH15,DLG2,KLRC2,FAM66C,DPP6,SLC6A15,CRTAC1,ZYG11B,JMJD1C,RPRD1A,SLC4A10,EPB41L1" MicroRNA hsa-miR-23b:PITA hsa-miR-23b:PITA_TOP PITA 1.61E-23 8.70E-20 8.61E-23 7.90E-22 55 799 "RIMKLA,LGR4,EYA1,KLHL32,ADD3,NLGN4X,KIAA1109,PKP4,MAGI3,MIER1,MADD,RUFY2,SPHKAP,PHYHIPL,PALLD,B3GALT2,CAB39,NEK6,DNER,ERBIN,SEPT3,GLS,SYT4,CAMTA1,CAMSAP2,ANO4,ZEB1,NRGN,NUDT21,PSD3,GPR88,TGFBR3,TJP1,REPS2,DCLK1,TPM3,PDE4B,FNDC5,CADM1,NRXN1,NEGR1,TJP2,DNAJC12,TENM4,TOX,SIRPA,DNAJC6,SRGAP3,SNX27,DLG2,WIPF2,SLC17A6,JMJD1C,INSYN2,SLC4A10" MicroRNA hsa-miR-23a:PITA hsa-miR-23a:PITA_TOP PITA 1.61E-23 8.70E-20 8.61E-23 7.90E-22 55 799 "RIMKLA,LGR4,EYA1,KLHL32,ADD3,NLGN4X,KIAA1109,PKP4,MAGI3,MIER1,MADD,RUFY2,SPHKAP,PHYHIPL,PALLD,B3GALT2,CAB39,NEK6,DNER,ERBIN,SEPT3,GLS,SYT4,CAMTA1,CAMSAP2,ANO4,ZEB1,NRGN,NUDT21,PSD3,GPR88,TGFBR3,TJP1,REPS2,DCLK1,TPM3,PDE4B,FNDC5,CADM1,NRXN1,NEGR1,TJP2,DNAJC12,TENM4,TOX,SIRPA,DNAJC6,SRGAP3,SNX27,DLG2,WIPF2,SLC17A6,JMJD1C,INSYN2,SLC4A10" MicroRNA hsa-miR-203:PITA hsa-miR-203:PITA_TOP PITA 1.67E-23 9.01E-20 8.92E-23 8.18E-22 49 625 "ARID1A,SCN3A,SEMA6A,BCAR3,ELMOD1,FOXG1,DOCK10,APC,API5,SLC1A2,SLC7A14,ARHGAP5,YPEL4,DACH2,CAB39,NMNAT2,CLASP2,BCL2L2,PHLDB1,NEUROD1,GLS,CAMSAP2,CACNA1E,TCF12,NUDT21,ADAMTS8,INA,TLL2,CDH10,PCSK2,MAGI1,HPCA,NEGR1,FAT3,NXPH1,MAPK10,EDRF1,FGFR1OP2,LRRTM3,PTCH1,KCNMA1,KIF2A,SLC17A6,C12orf4,RGS7,FAM135B,RAVER2,EN2,TMEM100" MicroRNA hsa-miR-2909:mirSVR_lowEffct hsa-miR-2909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-23 9.25E-20 9.14E-23 8.38E-22 61 989 "CDHR1,SLC25A25,NDRG2,TOMM40L,MOBP,SOX6,SFPQ,USP28,PPFIA1,ANXA7,DOCK10,NTNG1,BCAS1,SLC14A1,RCOR3,TMEM108,SOX5,ARPP21,TTLL9,NAP1L2,LMO3,CLASP2,BCL2L2,NEUROD1,SLCO1C1,PCDH11X,ATF7,CAMK2G,CECR2,VSTM2A,FBXL16,NEURL1,PCDH8,MS4A7,TMEFF2,CAMKV,CCSER2,PMP2,SF1,SNCAIP,MICAL2,ATRNL1,RAB39A,SPIRE1,PRDM2,ZC3H11A,OCIAD1,PTPRE,PTPRZ1,KCNK1,KCNK2,SLC17A6,FAM13C,DTNA,ABCC9,INSYN2,TTLL7,SEC61A2,SLC39A12,ABI2,EPB41" MicroRNA hsa-miR-198:mirSVR_highEffct hsa-miR-198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-23 9.47E-20 9.35E-23 8.58E-22 56 831 "SORCS1,FCGR1B,FGF14,USP28,CNIH2,PPFIA1,ST3GAL3,AQP4,MSR1,ARFGAP2,SCMH1,CAPRIN2,ATP1A3,DKK3,ENKUR,JPH4,ADAM15,KIF1B,FXYD6,AJAP1,CASTOR3,ASTN2,DDHD2,CACNB2,DDR2,SYT6,GRIA2,LEFTY2,INA,TMEM257,HPS5,CDC42,ARHGAP19,CHGA,JAM2,GDAP1L1,NRXN1,A2ML1,NXPH1,CNRIP1,CP,SNCAIP,OSBPL3,NRSN1,DNAJC6,HP1BP3,PTPRE,KCNK2,PCDH15,PEX5,DBX2,RFX5,FAM135B,ARHGEF10L,RCAN2,SEZ6" MicroRNA hsa-miR-138:mirSVR_highEffct hsa-miR-138:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.76E-23 9.50E-20 9.37E-23 8.60E-22 57 862 "CLIP1,GPR158,BCAR3,SELL,ITSN1,PKP4,SH3GL2,GPAM,RPH3A,CCDC88A,SCG3,ATM,SNCB,ATP2B2,USP33,NFASC,NEUROD1,ZNF638,KAZN,WWC1,CACNB2,GRIA4,GRIK3,CRB1,TPM4,BEST3,HERC2P3,OPALIN,FTO,BEST1,NXPH1,MFSD4A,CHD1L,SNCAIP,CSF3R,RBPJ,PRKCG,PLPP4,ELMO1,OCIAD1,TMCC2,CCDC3,KCNK1,PCDH15,NKAIN1,PID1,RALGDS,C12orf4,DTNA,ZYG11B,RFX4,JMJD1C,SSPN,SLC4A10,YY1AP1,PRRT4,RCAN2" MicroRNA hsa-miR-548v:mirSVR_highEffct hsa-miR-548v:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.83E-23 9.89E-20 9.75E-23 8.94E-22 54 771 "RTN3,WLS,RTN1,RXRG,HOGA1,KIAA1109,LRRC7,PKP4,NTNG1,SLC6A9,CGREF1,IGSF9B,ATP2B2,PALLD,SOX1,AJAP1,ZNF638,UNC5D,ANO4,GPM6B,TCF7L2,B4GALNT4,GPR17,TCF12,PTBP2,NUDT21,CRB1,TGFBR3,INA,MAGI1,SULT4A1,P2RY12,CP,POU3F2,MED1,SNCAIP,PRKACB,DZIP3,USP54,CTNND1,BRINP3,TOX,KIAA0513,DPYSL5,SYNC,JAKMIP2,PRDM2,HP1BP3,MAGI2,PTPRO,FAM66C,DPP6,PAK5,RFX4" MicroRNA hsa-miR-148a*:mirSVR_highEffct hsa-miR-148a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-23 1.01E-19 9.95E-23 9.13E-22 77 1554 "TMEM74,CNTNAP3,RCSD1,ARID1A,CLIP1,AMER2,GPR158,LINC00461,KIAA1109,SGIP1,PKP4,DOCK10,GPAM,NLGN1,ST3GAL3,MIER1,CCDC88A,CGREF1,DDX25,SMARCE1,RCOR3,EIF4G3,ATP2B2,TNIK,CAB39,KIF1B,DNER,PCDH11X,UNC5D,ADGRL3,PRUNE2,VWC2,DDR1,ZEB1,TCF12,GRIA1,GRIA4,GPR88,GRM3,CRB1,INA,ZDHHC22,PDYN,BEST3,HMGB1,ANLN,OPALIN,CELF5,BTF3L4,SPATA6,CHD1L,SNCAIP,DOCK7,PRKCG,PLD5,USP54,PUM1,EDRF1,TOX,SPIRE1,TOMM20,BDNF-AS,PTHLH,PTPRD,NTM,RABGAP1L,KCNK1,PCDH15,DLG2,DNAH9,DPP6,ATG16L1,GNE,BSDC1,SEC61A2,RBM12,RCAN2" MicroRNA hsa-miR-563:mirSVR_lowEffct hsa-miR-563:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-23 1.06E-19 1.05E-22 9.59E-22 56 833 "ABAT,ADGRV1,WLS,RTKN,ERMN,BBOX1,SLC30A10,SOX6,PPFIA1,ANXA7,NTNG1,SHTN1,SLC2A5,MSR1,CADPS,SLN,TMEM108,NDUFA5,PHLDB1,NEUROD1,PCDH11X,ZNF638,CAMSAP2,UNC5D,BTRC,ADGRL3,KLHL4,PTBP2,BRSK2,GRIA1,LINC00839,CRB1,TLL2,TMEM257,PCDH9,CDH8,CADM1,TJP2,VCAN,RBPJ,PRKCZ,IGSF1,CTNND2,PUM1,ZBTB16,DPYSL5,GON4L,TOMM20,LRRTM3,JAKMIP2,PTPRE,KCNMA1,DPP6,C12orf4,DTNA,TMEM100" MicroRNA hsa-miR-548l:PITA hsa-miR-548l:PITA_TOP PITA 2.17E-23 1.18E-19 1.16E-22 1.06E-21 50 657 "LGR4,F3,ADCY2,CDC42BPA,APC,GAS7,NLGN1,ARHGAP5,ASCL1,SMARCE1,SNAP25,MEGF11,CAB39,LHFPL4,KIF1B,CPLX2,NCAM1,CLASP2,NFIA,PCDH11X,GPM6A,CACNB2,PTBP2,EML4,ZFP91,TNS1,RBFOX2,JAM2,NEGR1,ANLN,CNTN1,MEAF6,POU3F2,MED1,PHACTR3,PKN2,PUM1,TOX,WBP1L,DNAJC6,KCNA1,KCNK1,DLG2,TMEM255A,ATG16L1,GOPC,FAM13C,DTNA,PAK5,SFXN5" MicroRNA hsa-miR-96*:mirSVR_highEffct hsa-miR-96*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-23 1.18E-19 1.16E-22 1.06E-21 67 1196 "PRR5L,CNTNAP3,WLS,MDM4,CDC7,ERMN,SCN3A,LRRTM4,LINC00461,LRRC7,ELMOD1,AMPH,ANXA7,SLITRK3,NLGN1,API5,ZNF365,SPHKAP,ASPH,DKK3,WDTC1,KIF1B,NELL1,SLCO1C1,FAM168A,NODAL,CAMSAP2,UNC5D,GOLGB1,ACSL6,DDR1,ZEB1,PTBP2,VXN,GRIA4,GPR88,TGFBR3,AIFM1,PCDH9,BEST3,CASC2,NEGR1,TJP2,CNTN1,PACSIN1,CNRIP1,PRKACB,DOCK7,MASP1,GON4L,DNAJC6,ITGAV,BDNF-AS,HP1BP3,LRP8,STMN4,ZC3H11A,OCIAD1,PTPRD,PTPRO,NTM,AK5,DTNA,SLC6A15,RERGL,C2orf80,RCAN2" MicroRNA hsa-miR-505:mirSVR_highEffct hsa-miR-505:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.33E-23 1.26E-19 1.23E-22 1.13E-21 61 995 "ABAT,C1orf194,ACER3,ACTN2,KLHL32,PPFIA1,ITSN1,BCAS1,SHTN1,MIER1,SLC8A3,SPHKAP,SLN,SORCS3,SNAP25,PHYHIPL,SON,MYT1L,GART,NCAM1,CLASP2,NEUROD1,SEPT3,AJAP1,GLS,ZNF638,GPM6A,LILRA1,VXN,GRIA2,GRIA4,CRB1,INA,PAH,MAGI1,LINC01102,HMGB1,CHI3L2,CADM1,UBTF,VAV2,CP,POU3F4,CHD1L,SF1,PPP3CB,KCNT2,VCAN,DZIP3,ZNF385B,PSMD13,BDNF-AS,PRDM2,PTPRO,KCNMA1,SLC6A15,RET,RFX4,SLC4A10,RCAN2,LRRC23" MicroRNA hsa-miR-499-5p:mirSVR_highEffct hsa-miR-499-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.51E-23 1.36E-19 1.33E-22 1.22E-21 68 1234 "EPS8,SYT9,RTKN,MDM4,CSMD3,ADORA3,SLC44A5,TESK2,SCN3A,KIAA1109,FOXG1,SGIP1,ITSN1,SYBU,MIER1,SLC8A3,RCOR3,SON,SOX5,AHCYL1,GART,COLGALT2,NDUFA5,FAM168A,GLS,VAMP1,DCLK2,CACNB2,ZEB1,AZIN2,PTBP2,EML4,NUMA1,OMG,CDC42,MAGI1,BEST3,CASC2,MS4A7,CADM1,A2ML1,BEST1,ACBD5,RNF14,KCNT2,FEZ1,OSBPL3,ATRNL1,VCAN,RBPJ,PTCH1,DNAJC6,CADM2,KCNK1,PCDH15,KCNMA1,RASGRF1,ABCC9,SLC6A15,ZYG11B,RET,RGS7,SYT15,RNF220,SLC39A12,SLC4A10,TMEM100,EPB41L2" MicroRNA hsa-miR-323b-5p:mirSVR_lowEffct hsa-miR-323b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.60E-23 1.41E-19 1.38E-22 1.26E-21 64 1097 "ABAT,PRR5L,PAQR6,ECSIT,LDLRAD3,LRRTM4,PPM1E,AQP4,ZNF365,SHANK2,CADPS,CAPRIN2,SORCS3,DKK3,SON,MYT1L,KIF1B,NFASC,NCAM1,COLGALT2,FGF17,RND1,SEPT3,PCDH11X,ZNF638,UNC5D,TBX15,GRIA1,GPR88,GRM3,CCKBR,CRB1,P2RX7,PADI2,PCDH8,PCDH9,CDH8,LGI1,MAGI1,PDYN,PFKFB3,ZBED5,TJP2,PMP2,CNRIP1,CRMP1,NCAN,PRKCZ,CTNND2,BRINP3,JAKMIP2,BDNF-AS,CADM2,PRDM2,KCNC1,KCNJ9,CCDC3,KCNK2,DLG2,DNM2,PARP11,C12orf4,FAM135B,RAVER2" MicroRNA hsa-miR-1297:mirSVR_highEffct hsa-miR-1297:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.09E-23 1.67E-19 1.64E-22 1.50E-21 69 1274 "CNTNAP3,LGR4,ACTN2,RTN1,SORCS1,FGF14,MOG,SEMA6C,SFPQ,SGIP1,ANK1,ANK2,APC,NLGN1,SHTN1,MIER1,RUFY2,CCDC88A,DACH2,SLCO1A2,SORCS3,ATP1A2,PALLD,USP33,MYT1L,ZCCHC24,ARPP21,NEK6,NPAS3,CLASP2,STOX1,GLS,VAMP1,ZNF638,SYT4,POPDC3,KLHL4,CACNB2,NUMA1,GRIA4,RFFL,PCDH9,LGI1,PDE3B,LINC01102,BEST3,PFKFB3,NRXN1,TJP2,PMP2,CELF5,ACBD5,PPP2R5C,SNCAIP,PPP3CB,DZIP3,CTNND2,ANKS1B,TUBB2B,JAKMIP2,PTPRD,PLPPR4,KCNK1,DLG2,RALGDS,SLC6A15,ZYG11B,VANGL2,RBM12" MicroRNA hsa-miR-20a-5p:TargetScan hsa-miR-20a-5p TargetScan 3.10E-23 1.68E-19 1.64E-22 1.50E-21 60 968 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-93-5p:TargetScan hsa-miR-93-5p TargetScan 3.10E-23 1.68E-19 1.64E-22 1.50E-21 60 968 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-20b-5p:TargetScan hsa-miR-20b-5p TargetScan 3.10E-23 1.68E-19 1.64E-22 1.50E-21 60 968 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-193a-5p:mirSVR_lowEffct hsa-miR-193a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-23 1.70E-19 1.65E-22 1.51E-21 68 1239 "TMEM74,F3,GALNT13,FOXRED2,NLGN4X,TESK2,FGF14,SLC30A10,SFPQ,DOCK10,MAGI3,JAKMIP3,MSR1,SLC14A1,SLIT1,RCOR3,SCN3B,SON,SOX1,TNIK,AHCYL1,NMNAT2,ARPP21,LHFPL4,DNER,ALDH1L1,PHLDB1,SEPT3,GPR17,TCF12,CAMK2G,NUMA1,GRIA2,VWCE,CRB1,TJP1,ZDHHC22,CDK11B,HPS5,PADI2,LRTM2,TUB,NLGN3,NRXN1,NEGR1,A2ML1,ST8SIA5,SULT4A1,SPATA6,NSD2,ATCAY,CHD1L,CRLS1,FEZ1,PRKACB,FAM131B,SYTL2,DPYSL5,PRDM2,KCNH1,KCNJ10,RAB3IL1,SLC17A6,SUSD4,ABCC9,JMJD1C,TTLL7,RASGRP2" MicroRNA hsa-miR-106a-5p:TargetScan hsa-miR-106a-5p TargetScan 3.27E-23 1.77E-19 1.72E-22 1.58E-21 60 969 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-17-5p:TargetScan hsa-miR-17-5p TargetScan 3.27E-23 1.77E-19 1.72E-22 1.58E-21 60 969 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-106b-5p:TargetScan hsa-miR-106b-5p TargetScan 3.27E-23 1.77E-19 1.72E-22 1.58E-21 60 969 "RIMKLA,LDLRAD3,ADAR,F3,AMER2,NTNG1,RUFY2,LRRC55,CAPRIN2,ATP1A2,FYN,ATP2B2,PALLD,MYT1L,B3GALT2,GAD2,SALL3,KIF1B,NPAS3,LMO3,BCL2L2,RGL1,AJAP1,FAM168A,ARHGEF7,NHLH1,NKX2-2,KCNK10,REPS2,HPS5,PDE3B,GPR37L1,PFKFB3,CCSER2,PRRX1,FAT3,ACBD5,CHD5,PRKACB,PKN2,NRSN1,FAM131B,PSD,KIAA0513,DPYSL5,PTHLH,CADM2,HP1BP3,LRP8,RGMA,CEP170,PTPRD,KCNJ10,NAV2,RAB5B,DNM2,ATG16L1,ABI1,FAM13C,ARHGAP12" MicroRNA hsa-miR-3065-3p:mirSVR_highEffct hsa-miR-3065-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.28E-23 1.78E-19 1.72E-22 1.58E-21 56 842 "SDE2,RTN3,RCSD1,MDM4,KLHL32,SLITRK1,WAC,CDC7,HOGA1,NLGN1,SHTN1,SMARCE1,WDTC1,SOX5,ZSWIM8,KIF1B,NCAM1,C11orf87,GNAS,MMD2,ACSL6,DDR1,PTBP2,CAMK2G,GRIA1,GRID1,GRIK2,TMEM9,HRH3,ZMYND8,BEST3,NRXN1,MFSD4A,CRMP1,PPP2R5C,PRKACB,PRKCG,PRKCZ,NRSN1,MASP1,PTHLH,CADM2,PLPPR4,C1orf109,PCDH15,PEX5,ABI1,DTNA,RET,RFX4,ATL1,VWA5A,SLC4A10,PRRT4,EPB41L2,RCAN2" MicroRNA hsa-miR-1257:mirSVR_highEffct hsa-miR-1257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.49E-23 1.89E-19 1.83E-22 1.68E-21 61 1003 "ABAT,CSMD2,ARID1A,GALNT13,PKP4,ZCCHC17,SORBS1,NLGN1,API5,MIER1,SLC1A6,CCDC88A,SHANK2,CADPS,ASCL1,SPHKAP,ASPH,RCOR3,NRG3,SON,KIF1B,NPAS3,NCAM1,LMO3,CLASP2,ADHFE1,RND1,ADGRL3,PRUNE2,NUDT21,CCKBR,CRB1,LGI1,CADM1,NRXN1,PLXNB3,BTF3L4,SPATA6,RNF14,SNCAIP,KCNT2,FEZ2,MICAL2,NCAN,USP54,IGSF1,CTNND2,NRSN1,SPIRE1,PLPPR5,DNAJC6,CA10,PLPPR1,PTHLH,ZC3H11A,PTPRO,KCNK2,RGS7,RERGL,TMEM100,UEVLD" MicroRNA hsa-miR-876-5p:mirSVR_highEffct hsa-miR-876-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.54E-23 1.92E-19 1.86E-22 1.70E-21 66 1172 "RPL38,ARID1A,RTN1,WAC,SORCS1,NLGN4X,TOMM40L,TESK2,SEMA6A,FOXM1,ANK1,ANK2,ANK3,FOLH1,ITSN1,PPM1E,APBA2,MAGI3,USP16,RUFY2,MSR1,MSRA,SMARCE1,ATP2B2,PALLD,SOX5,EMC1,SPART,ZNF302,GANAB,CASTOR3,SYT4,GNAS,DDHD2,GPM6A,LRIT2,SYT6,GRIA4,PAH,PAX6,TPM4,PDYN,HMGB1,MS4A7,CADM1,KIAA1549L,NEGR1,DNAJC12,PMP2,MED1,SNCAIP,FEZ1,PRKACB,NRSN1,DNAJC6,MAGI2,OLFM3,PTPRE,KCNN3,DLG2,SLC25A48,RALGDS,RFX5,JMJD1C,EPB41,UEVLD" MicroRNA hsa-miR-3179:mirSVR_highEffct hsa-miR-3179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.62E-23 1.96E-19 1.90E-22 1.74E-21 57 875 "RABEPK,ACLY,ATAT1,SLITRK1,SORCS1,FGF1,APC,CACHD1,CCDC88A,ASPH,SORCS3,ATP1A3,EIF4G3,SON,WDTC1,JPH4,KIF1B,STOX1,DCAF5,GANAB,VAMP1,PCDH11X,SEMA4A,ADGRL3,CACNB2,HAP1,SYT6,INA,PCDH9,TPD52,TLX1,ZFYVE9,FAM181B,CNTN1,POU3F4,PNKD,PPP3CB,PRKACB,FMN2,KIAA1755,NRSN1,PTAFR,CA10,ITIH2,OLFM3,SMG7,SNX27,RAB5B,PID1,SLC25A18,L1CAM,PHC2,ZNF248,SSPN,PIANP,EFNA3,EPB41" MicroRNA hsa-miR-3144-5p:mirSVR_lowEffct hsa-miR-3144-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.68E-23 1.99E-19 1.92E-22 1.76E-21 61 1004 "MAP6,NLGN4X,LINC00461,PLA2G6,ASIC4,UNC79,FOXM1,API5,ZNF365,MIER1,RPH3A,SLC6A9,ARFGAP2,MT3,PDE8B,NAXD,KBTBD12,TMEM151A,ATP1A2,FYN,WDTC1,CADM3,JPH4,KIF1B,NPAS3,NCAM1,KIRREL3,AJAP1,KAZN,PCDHGA3,AKNA,CYB561A3,SHISA7,CRB1,SPX,PC,ZNF384,CASC2,HPCA,GDAP1L1,PLXNB3,C11orf49,COL9A2,NSD2,MED1,PLCH2,MASP1,ZBTB16,PLPPR5,SYNC,ZC3H11A,PTPRE,KCNJ11,KCNMA1,DLG2,PYGM,WIPF2,L1CAM,ABCC9,VANGL2,RLBP1" MicroRNA hsa-miR-486-3p:mirSVR_highEffct hsa-miR-486-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.75E-23 2.03E-19 1.96E-22 1.80E-21 51 694 "RTN3,MDM4,CDC7,SLC44A5,SNX32,TESK2,CNIH2,ITSN1,CACHD1,ST3GAL3,MSR1,LRRC55,YPEL4,MT3,TAGLN3,ASPH,ATP1A3,MEGF11,SOX10,INKA2,ADHFE1,PHLDB1,SEPT3,SLCO1C1,CDK5R2,ANO4,TCF12,VXN,RFFL,INA,HRH3,PDE2A,FNDC5,CASC2,JAM2,KIAA1549L,SEMA5B,BEST1,POU3F2,PNKD,MICAL2,PRKCG,ECE2,SYTL2,SIRPA,KCNA2,KCND3,KCNJ10,RNF220,BSCL2,BAALC" MicroRNA hsa-miR-1284:PITA hsa-miR-1284:PITA_TOP PITA 3.81E-23 2.06E-19 1.99E-22 1.82E-21 41 427 "EPS8,ABAT,LDLRAD3,ANK1,ITSN1,SLITRK3,SORBS1,SLC1A2,ATP2B2,B3GALT2,NASP,NFASC,NCAM1,SMOC1,ERBIN,GFRA1,VAMP1,CAMTA1,WWC1,ANO4,CACNB2,PSD3,RBFOX2,ZNF384,PDE4B,HMGB1,NRXN1,PPP3CB,FEZ1,PUM1,PTCH1,CSDE1,KCNMA1,DLG2,RTN4,SLC6A15,RBM12,ARHGAP12,CBLN2,EPB41L2,RCAN2" MicroRNA hsa-miR-4274:mirSVR_highEffct hsa-miR-4274:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.22E-23 2.28E-19 2.20E-22 2.02E-21 46 556 "RABEPK,ARID1A,KCNIP2,WAC,ERMN,LRRTM4,DISP3,LRRC7,ELMOD1,MOBP,FOXG1,API5,PHYHIPL,PALLD,GABBR1,KIF21B,ILDR2,PHLDB1,DCLK2,KAZN,ANO4,ACSL6,CACNA1E,CACNB2,VXN,VSTM2A,GRIA2,PCDH9,LGI1,CASC2,A2ML1,FTO,CNTN1,SPATA6,VCAN,NCAN,PKN2,ANKS1B,SIRPA,PEX5,RAB5B,TMEM255A,SLC6A15,SEC61A2,GPR61,C2orf80" MicroRNA hsa-miR-337-3p:mirSVR_lowEffct hsa-miR-337-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.27E-23 2.31E-19 2.22E-22 2.04E-21 68 1246 "SDE2,ZFYVE27,IL17D,ATAT1,CSMD3,KLHL32,HPCAL4,MOBP,FOXG1,ASRGL1,PKP4,SORBS1,NLGN1,JAKMIP3,MSRA,SLC8A3,ASCL1,SCG3,SNAP25,EIF4G3,SOX5,C11orf87,ERBIN,PCDH11X,ZNF638,LUZP2,UNC5D,WWC1,KLHL4,ACSL6,TCF12,CECR2,LINC00839,TGFBR3,CASC2,GDAP1L1,NMT2,SF1,PPP2R5C,FMN2,NRSN1,HES5,ECE2,TOX,ANKS1B,TOMM20,PLPPR5,PRDM2,CEP170,CSDE1,PTPRD,SMG7,PLPPR4,KCNC1,C1orf109,KCNJ9,PCDH15,DNM2,DBX2,DTNA,CRTAC1,RET,RFX4,VANGL2,SYT15,ARHGAP12,RPE65,TMEM100" MicroRNA "TGCTTTG,MIR-330:MSigDB" "TGCTTTG,MIR-330:MSigDB" MSigDB 4.31E-23 2.33E-19 2.24E-22 2.06E-21 36 314 "KCNIP2,ADD3,SORCS1,FOXG1,AMPH,SH3GL2,PPM1E,APC,GPAM,SYBU,API5,SLC8A3,ATP2B2,ZCCHC24,ARPP21,KIF1B,PCDH11X,BTRC,GPM6A,TCF12,GRID1,TGFBR3,TJP1,CELF3,DCLK1,TPM3,TOX,PRTFDC1,LRP8,CEP170,KCNA6,SLC17A6,PHC2,EFNA3,RBM12,SLC4A10" MicroRNA hsa-miR-576-3p:mirSVR_highEffct hsa-miR-576-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.69E-23 2.54E-19 2.44E-22 2.24E-21 60 976 "SYT9,LGR4,RTKN,KLHL32,SLITRK1,GALNT13,ADD3,CDC7,ERMN,MOG,AMPH,ERICH3,ITSN1,GPAM,CACHD1,BCAS1,RPH3A,CCDC88A,CAPRIN2,ATP2B2,MYT1L,CAB39,GAD2,ARPP21,TTLL9,IDI2-AS1,CLASP2,STOX1,ZNF638,ADGRL3,LRIT2,NPPA,BRSK2,GRIA2,INA,LGI1,PRMT8,BEST3,ANO5,PLEKHB1,TMEFF2,NXPH1,NCAN,USP54,LRP8,OLFM3,PTPRZ1,KCNK2,KCNMA1,DLG2,DNAH9,KLRC2,ATG16L1,RTN4,PAK5,SLC6A15,RFX4,JMJD1C,FGFBP3,RCAN2" MicroRNA hsa-miR-1909*:mirSVR_lowEffct hsa-miR-1909*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.69E-23 2.54E-19 2.44E-22 2.24E-21 60 976 "ACER3,MBP,CEND1,ACTN2,F3,SLITRK1,WAC,DRAXIN,TOMM40L,HOGA1,LINC00461,CDC42BPA,STK32C,URGCP,LRRC55,SLC8A3,SCG3,CAPRIN2,MTR,C10orf105,KBTBD12,ADGRA1,ATM,TNIK,TTLL9,ADAM15,ADGRB2,CLASP2,DCAF5,RND1,ACSBG1,CDK5R2,CCKBR,TGFBR3,CD81,PDYN,ADGRG1,ASIC3,TLX1,NLGN3,PLXNB3,PTPA,RGS6,OSBPL3,ATRNL1,SDC3,FAM131B,TOMM20,PRDM2,CEP170,PTPRO,KCNJ11,CCDC3,C12orf4,ABCC9,PHC2,ZNF248,SLC39A12,RAVER2,SEZ6" MicroRNA hsa-miR-1227:mirSVR_lowEffct hsa-miR-1227:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.99E-23 2.70E-19 2.59E-22 2.38E-21 74 1467 "ACER3,ACTN2,ADGRV1,WLS,MDM4,F3,ADD3,WAC,ERMN,BCAR3,BBOX1,MOBP,SELL,SGIP1,USP28,BCAS1,PAAF1,MIER1,SFMBT2,LRRC55,ARHGAP5,DACH2,CGREF1,CAPRIN2,ATM,ATP1A2,B3GALT2,TNIK,KIF21B,GAD2,KIF1B,NASP,INKA2,VAMP1,UNC5D,PRUNE2,FAM69C,NUDT21,NUCB1,GRIA4,GRM3,TJP1,TLL2,NEURL1,KCNK10,HPS5,TPM3,CASC2,MS4A7,GDAP1L1,CPT1C,NMT2,NSD2,CRMP1,OSBPL3,RBPJ,PRKAB2,DOCK7,USP54,NRSN1,MASP1,GON4L,PTAFR,PRDM2,CEP170,KCNJ10,KCNK2,ATG16L1,SUSD4,DTNA,SEC61A2,ARHGAP12,RAVER2,PRRT4" MicroRNA hsa-miR-203a-3p.1:TargetScan hsa-miR-203a-3p.1 TargetScan 5.14E-23 2.78E-19 2.67E-22 2.45E-21 50 670 "ACER3,RIMKLA,MAPT,MRVI1,ARID1A,BCAR3,ELMOD1,DOCK10,APC,CCDC88A,ATM,FYN,MEGF11,SCN3B,KIF21B,CAB39,GAD2,NMNAT2,RAP1GAP2,FAM168A,GLS,KAZN,CAMTA1,GNG4,CAMSAP2,BTRC,PTBP2,NUDT21,GUCY1A2,KCNK10,CDH10,NEGR1,FAT3,NXPH1,MICAL2,RIMS4,MAPK8,MAPK10,LRRTM3,PTCH1,CADM2,KCNN3,KIF2A,C12orf4,FAM135B,ARHGAP12,RAVER2,EN2,EPB41,EPB41L1" MicroRNA hsa-miR-202*:mirSVR_lowEffct hsa-miR-202*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.79E-23 3.14E-19 3.00E-22 2.76E-21 72 1397 "ABAT,ACER3,MAP6,MBP,DUSP27,ATAT1,RTKN,SLITRK1,SORCS1,HOGA1,LRRC7,FHL1,MOBP,TRIM46,DOCK10,APC,TACC2,ST3GAL3,API5,SLC2A5,LRRC55,SLCO1A2,EIF4G3,PALLD,SOX5,AHCYL1,NMNAT2,KIF1B,NFIA,PCDH11X,KAZN,GNG4,MYRF,UNC5D,GOLGB1,ANO4,TCF7L2,NUDT21,GRIA1,GRIN1,ZDHHC22,RBFOX2,LGI1,LINC01102,HEPACAM,ANLN,DNAJC12,PMP2,NSD2,ACBD5,PPP3CB,PRKCZ,CTNND2,ECE2,ZBTB16,ZNF385B,PTHLH,HP1BP3,KCNA2,OCIAD1,SMG7,KCNK2,PCDH15,NAV2,DBX2,PAK5,INSYN2,ATL1,ZNF248,RBM12,RPE65,BAALC" MicroRNA hsa-miR-556-3p:mirSVR_highEffct hsa-miR-556-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.81E-23 3.15E-19 3.01E-22 2.76E-21 63 1080 "EPS8,WLS,CSMD3,F3,ADARB2,SORCS1,FCGR1B,SCN3A,KIAA1109,FGF1,USP28,MIER1,NSG2,ASCL1,SLCO1A2,ENKUR,KIF1B,ALDH1L1,NDUFA5,SLCO1C1,GLS,PCDH11X,ZNF638,DDHD2,ADGRL3,DDR1,CACNB2,TCF7L2,ZEB1,EML4,GRIA2,GRIA4,GRIK2,TMEM257,PAH,TNR,PCDH9,PCSK2,CASC2,C11orf49,BTF3L4,PACSIN1,FAT3,NXPH1,MFSD4A,CP,MED1,PPP2R5C,IGSF1,SIRPA,PTHLH,CADM2,PRTFDC1,LRP8,C1orf109,KCNH1,KCNK2,KLRC2,PID1,ABCC9,NUP214,ZNF248,RAVER2" MicroRNA hsa-miR-769-3p:mirSVR_lowEffct hsa-miR-769-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.91E-23 3.20E-19 3.05E-22 2.80E-21 71 1361 "ABAT,C1orf194,SYNDIG1,MEG3,ATAT1,GALNT13,SORCS1,ERMN,ADORA1,LRRTM4,HPCAL4,ERICH3,DOCK10,BCAN,CACHD1,NLGN1,ST3GAL3,SLC8A3,SPHKAP,ASTN1,B3GAT1,SNCB,MEGF11,USP33,ZSWIM8,STARD10,FXYD6,NCAM1,NCDN,ZNF638,NHLH1,CAMTA1,PRUNE2,GPR17,SHISA7,CRB1,MAGI1,PDYN,ZBED5,DLGAP3,GDAP1L1,MEAF6,BEST1,COL9A2,NSD2,SF1,NCAN,PRKAB2,FMN2,ZBTB16,DPYSL5,TOMM20,DNAJC6,PRDM2,MAGI2,OLFM3,OCIAD1,SRGAP3,NTM,KCNJ10,KCNK2,PCDH15,DLG2,CAB39L,RALGDS,CRTAC1,RFX4,RGS7,ZNF248,VANGL2,RERGL" MicroRNA hsa-miR-105:PITA hsa-miR-105:PITA_TOP PITA 6.45E-23 3.49E-19 3.33E-22 3.06E-21 41 433 "LDLRAD3,CLIP1,SLITRK1,SOX6,GPAM,TACC2,API5,CCDC88A,SNAP25,SOX1,CADM3,CAB39,RND1,CAMTA1,CAMK2G,GRIA2,GRIA4,GRID1,INA,TJP1,MAEL,PCDH9,CIART,HMGB1,HNRNPK,TMEFF2,NRXN1,BTF3L4,PACSIN1,MED1,PRKAB2,PKN2,CA10,HP1BP3,PTPRE,DLG2,RAB5B,PAK5,ST8SIA3,SSPN,RBM12" MicroRNA hsa-miR-449c:mirSVR_highEffct hsa-miR-449c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-23 3.58E-19 3.41E-22 3.13E-21 62 1049 "MBP,ATAT1,MDM4,GPR158,SCN3A,LRRC7,FGF14,FHL1,ELMOD1,SLC30A10,ANK2,ANK3,ITSN1,ST3GAL3,API5,ASCL1,SCG3,CAPRIN2,ATM,PALLD,SON,MYT1L,TNIK,ARPP21,KIF1B,NPAS3,RAP1GAP2,CLASP2,ERBIN,ADHFE1,NEUROD1,GLS,GNAS,GOLGB1,CACNA1A,GPM6B,ZEB1,PTBP2,TMEM25,LGI1,MAGI1,PDE3B,UBTF,SULT4A1,NSD2,SF1,CTNND2,PUM1,MASP1,TOX,ANKS1B,CA10,CADM2,KCNA1,RABGAP1L,ARNT2,KCNMA1,DPP6,RAP1GAP,DTNA,JMJD1C,C2orf80" MicroRNA hsa-miR-1322:mirSVR_lowEffct hsa-miR-1322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.41E-23 4.01E-19 3.82E-22 3.51E-21 74 1477 "ACER3,KLHL32,ADD3,SNX32,FGF1,SESN3,APC,SORBS1,ZNF365,BCO1,MSR1,LRRC55,CGREF1,SLCO1A2,LGI3,ASPH,USP33,TNIK,ZSWIM8,ENKUR,CPLX2,NAP1L2,FXYD6,NFASC,CLASP2,NDUFA5,STOX1,NEUROD1,SEPT3,AJAP1,KLHL4,ANO4,TCF7L2,ZEB1,AZIN2,PCDHGA3,GRIA1,GRIA4,PTPN5,TMEM9,GUCY1A1,TLL2,CELF3,KCNK10,PCSK2,PDE3B,ZMYND8,ASIC3,HNRNPK,TJP2,BEST1,COL9A2,SLC36A4,NSD2,ACBD5,PPP2R5C,OSBPL3,CMTM5,GON4L,PLPPR5,DNAJC6,JAKMIP2,MAGI2,KCNA2,OCIAD1,PTPRD,PTPRO,RABGAP1L,KLRC2,FAM13C,RTN4,PAK5,SEC61A2,RAVER2" MicroRNA hsa-miR-30c-2*:mirSVR_highEffct hsa-miR-30c-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.72E-23 4.18E-19 3.98E-22 3.65E-21 64 1120 "MAG,RTN3,SLITRK1,ADORA3,GPR158,TESK2,SCN3A,KIAA1109,LRRC7,FHL1,MOBP,CDC42BPA,ITSN1,BCAN,SHTN1,MIER1,SLC8A3,SHANK2,SPHKAP,ASPH,GABBR1,MYT1L,ZSWIM8,AHCYL1,ADAM15,CLASP2,ALDH1L1,KIRREL3,SLCO1C1,ARHGEF7,SYT4,KAZN,KLHL4,CACNB2,VXN,SYT6,GRIA2,CYB561A3,CRB1,TMEM257,TPM3,PCSK2,NLGN3,KIAA1549L,BTF3L4,CHD1L,MED1,PPP2R5C,CTNND1,CTNND2,SPIRE1,LRRTM3,PRTFDC1,ZC3H11A,PTPRO,SV2A,KCNK2,RAB5B,DBX2,DTNA,RFX4,RNF220,SIDT2,EPB41" MicroRNA hsa-miR-190b:TargetScan hsa-miR-190b TargetScan 7.91E-23 4.28E-19 4.07E-22 3.73E-21 28 167 "RIMKLA,FGF14,ITSN1,ANXA7,NLGN1,NRG3,CPLX2,NFASC,NEUROD1,NFIA,CACNB2,GPR26,HAP1,GUCY1A2,PAX6,DCLK1,NEGR1,POU3F2,PTCH1,CA10,PTHLH,CEP170,MAGI2,BLOC1S6,KCNA4,KIF2A,ELAVL4,RCAN2" MicroRNA hsa-miR-190a-5p:TargetScan hsa-miR-190a-5p TargetScan 7.91E-23 4.28E-19 4.07E-22 3.73E-21 28 167 "RIMKLA,FGF14,ITSN1,ANXA7,NLGN1,NRG3,CPLX2,NFASC,NEUROD1,NFIA,CACNB2,GPR26,HAP1,GUCY1A2,PAX6,DCLK1,NEGR1,POU3F2,PTCH1,CA10,PTHLH,CEP170,MAGI2,BLOC1S6,KCNA4,KIF2A,ELAVL4,RCAN2" MicroRNA hsa-miR-943:mirSVR_lowEffct hsa-miR-943:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.22E-23 4.45E-19 4.23E-22 3.88E-21 71 1369 "TTYH1,MBP,SYNDIG1,WLS,AMER2,AMPH,ANK2,PPFIA1,PPM1E,DOCK10,MAGI3,CACHD1,BCAS1,CLSTN1,AQP4,ZNF365,MSRA,SLC14A1,SLCO1A2,KBTBD12,B3GAT1,ZSWIM8,ADAM15,SPART,NCAM1,CLASP2,COLGALT2,STOX1,ACSBG1,LUZP2,UNC5D,ADGRL3,CACNB2,EML4,CAMK2G,TMEM9,ATG4C,DAAM2,CDH8,TPM4,ZNF384,IGFN1,PDE4B,TMPRSS5,ARHGAP22,KIAA1549L,TJP2,C11orf49,NXPH1,RGS6,OSBPL3,PRKACB,PRKCG,PKN2,ARHGEF4,CTNND2,KIAA0408,SYNC,ITGAV,CADM2,KCNA4,PARD6A,KCNMA1,FAM66C,ABI1,GNE,SLC6A15,JMJD1C,ZNF248,ARHGAP12,EPB41L1" MicroRNA hsa-miR-548g:PITA hsa-miR-548g:PITA_TOP PITA 8.49E-23 4.60E-19 4.36E-22 4.00E-21 49 649 "ACER3,ARID1A,CSMD3,CDC42BPA,ANK3,GPAM,LRRC4C,ARHGAP5,CCDC88A,B3GAT1,SON,WDTC1,MYT1L,NCAM1,LMO3,CAMSAP2,GPM6A,CACNB2,TCF12,CECR2,PSD3,GRIA2,GPR88,TJP1,ZFP91,RBFOX2,NEGR1,NSD2,CRMP1,PPP2R5C,ATRNL1,PKN2,BRINP3,TOX,PTCH1,DNAJC6,ITGAV,PMEPA1,HP1BP3,CEP170,MAGI2,PTPRD,RAB5B,TMEM255A,ZYG11B,JMJD1C,VANGL2,RBM12,ABI2" MicroRNA hsa-miR-492:mirSVR_lowEffct hsa-miR-492:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.52E-23 4.61E-19 4.37E-22 4.01E-21 63 1088 "EMID1,HOGA1,FHL1,HPCAL4,FOXG1,FOXM1,CDC42BPA,ITSN1,SLC1A7,SLC8A3,SCG3,SORCS3,SCN3B,SOX1,IDI2-AS1,ALDH1L1,DCAF5,RND1,ARHGEF7,RHBDL3,GNAS,WWC1,DDR1,LILRA1,PTBP2,TMEM151B,VXN,DDR2,NUCB1,CYB561A3,CRB1,AIFM1,TLL2,ZFP91,PC,CHGA,CASC2,CHRNB2,CAMKV,SEMA5B,PMP2,BTF3L4,PRRX1,MED1,SNCAIP,PPP3CB,MICAL2,VCAN,PLPP4,HES5,SPIRE1,PSMD13,ELMO1,PRDM2,HP1BP3,C1orf109,RABGAP1L,NAV2,NKAIN1,DNAH9,ZNF248,RPRD1A,EPB41" MicroRNA hsa-miR-500:mirSVR_highEffct hsa-miR-500:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.69E-23 4.71E-19 4.45E-22 4.09E-21 69 1298 "CNTNAP3,LGR4,EYA1,CSMD2,CSMD3,GALNT13,SCN3A,SGIP1,USP28,PPFIA1,GPAM,CACHD1,PAAF1,MIER1,PKNOX2,CADPS,SORCS3,RCOR3,SNAP25,AHCYL1,C11orf87,COLGALT2,ZNF302,ERBIN,ADHFE1,ARHGEF7,GLS,PCDH11X,DDHD2,GOLGB1,KLHL4,ANO4,GPM6B,PTBP2,PCDHGA3,GRIA1,GUCY1A2,MAEL,DCLK1,LGI1,HMGB1,CCSER2,NXPH1,CNRIP1,RNF14,KCNT2,PRKACB,PRKCZ,EDRF1,SPIRE1,SYNC,LRRTM3,DNAJC6,PRDM2,MAGI2,BLOC1S6,OLFM3,OCIAD1,KCNK1,DLG2,FAM66C,NUP214,RFX4,RFX5,JMJD1C,RBM12,ELAVL4,TMEM100,BAALC" MicroRNA hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA_TOP PITA 8.92E-23 4.83E-19 4.56E-22 4.19E-21 43 487 "SLC25A25,KLHL32,ADD3,ANK3,ITSN1,SESN3,APC,SLC1A2,CCDC88A,EIF4G3,MEGF11,MYT1L,CADM3,CAB39,ENKUR,VAMP1,CAMTA1,UNC5D,BTRC,ADGRL3,PSD3,OPCML,TMEM257,PCSK2,FNDC5,HMGB1,HNRNPK,CADM1,NRXN2,RBPJ,CTNND1,TOX,ANKS1B,SYNC,PMEPA1,CEP170,ZC3H11A,PTPRZ1,SLC17A6,ABI1,PAK5,ARHGEF10L,OLIG2" MicroRNA hsa-miR-643:mirSVR_highEffct hsa-miR-643:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.28E-23 5.03E-19 4.75E-22 4.36E-21 62 1056 "ACER3,CNTNAP3,SYT9,LGR4,ATAT1,WAC,GPR158,LINC00461,BCAR3,FOXG1,MOG,ANK3,NTNG1,RUFY2,CCDC88A,MTR,SMARCE1,NRG3,B3GALT2,TTLL9,RGL1,NEUROD1,ZNF638,GNAS,MMD2,ANO4,CACNA1E,DDR1,ZEB1,TCF12,GRID1,OLR1,GUCY1A2,ZFP91,MAEL,LGI1,PDE1A,HMGB1,HNRNPK,NEGR1,PRRX1,ACBD5,CNRIP1,ATRNL1,PHACTR3,RBPJ,DZIP3,PRKCZ,CTNND1,TOX,ANKS1B,SYNC,PTHLH,CNIH3,OCIAD1,ABI1,FAM13C,RFX4,FAM135B,INSYN2,SLC4A10,UEVLD" MicroRNA hsa-miR-141-3p:TargetScan hsa-miR-141-3p TargetScan 9.69E-23 5.25E-19 4.95E-22 4.54E-21 49 651 "ADD3,ELMOD1,ANK2,ITSN1,PPM1E,CCDC80,MIER1,DNAH17,RCOR3,PHYHIPL,MYT1L,GAD2,NEK6,NPAS3,NFASC,NCAM1,LMO3,CLASP2,FAM168A,NFIA,CAMSAP2,GPM6B,CACNA1E,CDC42,PCDH8,CDH10,ACOT7,HMGB1,PLEKHB1,CADM1,KIAA1549L,NRXN1,CNTN1,NXPH1,POU3F2,CRMP1,NCAN,PRKACB,CTNND2,KIAA0408,PTCH1,CADM2,CEP170,MAGI2,PTPRD,PEX5,DLG3,JMJD1C,ELAVL4" MicroRNA hsa-miR-200a-3p:TargetScan hsa-miR-200a-3p TargetScan 9.69E-23 5.25E-19 4.95E-22 4.54E-21 49 651 "ADD3,ELMOD1,ANK2,ITSN1,PPM1E,CCDC80,MIER1,DNAH17,RCOR3,PHYHIPL,MYT1L,GAD2,NEK6,NPAS3,NFASC,NCAM1,LMO3,CLASP2,FAM168A,NFIA,CAMSAP2,GPM6B,CACNA1E,CDC42,PCDH8,CDH10,ACOT7,HMGB1,PLEKHB1,CADM1,KIAA1549L,NRXN1,CNTN1,NXPH1,POU3F2,CRMP1,NCAN,PRKACB,CTNND2,KIAA0408,PTCH1,CADM2,CEP170,MAGI2,PTPRD,PEX5,DLG3,JMJD1C,ELAVL4" MicroRNA "TGCCTTA,MIR-124A:MSigDB" "TGCCTTA,MIR-124A:MSigDB" MSigDB 9.70E-23 5.25E-19 4.95E-22 4.54E-21 44 514 "RTN3,EYA1,SCN4B,SEMA6A,SEMA6C,ANXA7,TACC2,JAKMIP3,CADPS,PALLD,ZCCHC24,NFASC,NEUROD1,ARHGEF7,MYRF,MMD2,GPM6B,CACNB2,PTBP2,GRIA2,GRID1,RFFL,KCNK10,PCDH8,PDE2A,NEGR1,CNTN1,PRRX1,SNCAIP,OSBPL3,ARHGEF4,KIAA0408,TOX,SYNC,PMEPA1,BLOC1S6,PTPRE,SRGAP3,KCNK2,NAV2,KCNQ2,SEC61A2,RAVER2,EN2" MicroRNA hsa-miR-383:mirSVR_highEffct hsa-miR-383:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.75E-23 5.28E-19 4.96E-22 4.55E-21 62 1057 "SERPINA3,SDE2,LOC100128239,LGR4,GALNT13,ADD3,ADORA3,TUBB4A,HOGA1,GOLGA7B,ELMOD1,NTNG1,ST3GAL3,MIER1,CSPG5,SPHKAP,ASPH,SON,SOX5,IDI2-AS1,SPART,C11orf87,CLASP2,RGL1,NEUROD1,GLS,ROBO3,ADGRL3,KLHL4,PRUNE2,VSTM2A,GRIA4,CYB561A3,SHISA7,CRB1,MFSD2A,TPD52,ZMYND8,HMGB1,MS4A7,NOMO2,A2ML1,TJP2,MEAF6,SLC36A4,NXPH1,PHACTR3,PRKCZ,IGSF1,SYTL2,PLPPR1,HP1BP3,KCNC1,KCNJ10,KCNK1,KCNK2,RAD52,SUSD4,DTNA,SLC6A15,RPRD1A,SLC4A10" MicroRNA hsa-miR-448:PITA hsa-miR-448:PITA_TOP PITA 9.94E-23 5.39E-19 5.06E-22 4.64E-21 41 438 "ABAT,SYT9,WLS,ADD3,ANK3,SH3GL2,GPAM,NLGN1,API5,KBTBD12,PHYHIPL,MYT1L,ZCCHC24,DCAF5,GLS,SYT4,GPM6A,ZEB1,PTBP2,PSD3,GRIK2,INA,CDC42,PCDH8,PCDH9,CDH10,SULT4A1,PRKAB2,PRKCZ,KIAA0408,TOX,DNAJC6,COPS7A,BLOC1S6,KCNA1,KCNA4,PTPRD,PTPRE,RAB5B,TTLL7,RAVER2" MicroRNA hsa-miR-199a-5p:mirSVR_highEffct hsa-miR-199a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-22 5.49E-19 5.16E-22 4.73E-21 54 800 "ZFYVE27,RCSD1,CLIP1,KLHL32,ADD3,CDC7,TESK2,LRRTM4,KIAA1109,ERICH3,ASRGL1,ANK3,ITSN1,APBB1,NTNG1,NLGN1,SORCS3,RCOR3,WDTC1,ENKUR,KIF1B,CLASP2,ADHFE1,RND1,DDHD2,CAMSAP2,ANO4,DDR1,ZEB1,GRIA2,GRIA4,CRB1,TMPRSS5,CASC2,JAM2,PIK3CD,POU3F2,CHD1L,CRLS1,RGS6,PRKAB2,SYTL2,LRP8,MAGI2,BLOC1S6,KCNK2,KCNMA1,SUSD4,ABI1,FAM13C,RGS10,INSYN2,SEC61A2,ARHGAP12" MicroRNA hsa-miR-92b:mirSVR_highEffct hsa-miR-92b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.06E-22 5.74E-19 5.38E-22 4.94E-21 56 863 "TMEM74,CSMD2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,ANK3,USP28,SESN3,TACC2,MIER1,MSR1,ASPH,PALLD,DKK3,B3GALT2,B4GALNT1,KIF1B,NPAS3,RGL1,PCDH11X,SYT4,CAMTA1,CNDP1,ANO4,GPM6A,CAMK2A,GRIA1,RFFL,AIFM1,CDH10,TPM4,PDE1A,SCRG1,CCSER2,CNRIP1,KCNT2,ATRNL1,RBPJ,FMN2,EDRF1,ITGAV,LRP8,PTPRD,PLPPR4,PTPRO,KCNK1,PEX5,TMEM255A,SLC17A6,PLEKHB2,BSDC1,SLC39A12,SLC4A10,RPE65" MicroRNA hsa-miR-3064-5p:TargetScan hsa-miR-3064-5p TargetScan 1.13E-22 6.09E-19 5.71E-22 5.24E-21 40 415 "RABEPK,PRR5L,RBM10,ADCYAP1R1,GRAMD1B,LCNL1,GOLGA7B,CCDC80,KIAA1614,CAPRIN2,C10orf105,DKK3,GABBR1,CADM3,B4GALNT1,CPLX2,BCL2L2,PHLDB1,FAM168A,MMD2,CNTN2,DIRAS1,CAMK2G,GRIK3,GUCY1A2,REPS2,PDE2A,IGFN1,CADM1,KIAA1755,CMTM5,JAKMIP2,RGMA,KCND3,KCNN3,KIF2A,RNF220,ELAVL3,PLEKHO1,EPB41L1" MicroRNA hsa-miR-153:mirSVR_highEffct hsa-miR-153:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.14E-22 6.15E-19 5.76E-22 5.29E-21 57 896 "F3,GALNT13,TMEM156,TOMM40L,TESK2,SCN3A,MOBP,SFPQ,ANK1,USP28,PPFIA1,ITSN1,PKP4,APC,SLC1A6,SLC14A1,TAGLN3,ASPH,SNAP25,NRG3,ATP2B2,ENKUR,NELL1,NEUROD1,GLS,RFFL,TJP1,CDC42,MAGI1,ZMYND8,HMGB1,TMEFF2,ZFYVE9,CCSER2,CCDC136,PMP2,TENM4,ATRNL1,DZIP3,PKN2,SYTL2,GON4L,ZNF385B,PTCH1,BDNF-AS,CADM2,PRDM2,KCNA1,PTPRD,NAV2,DLG2,FAM66C,DBX2,DTNA,SLC6A15,JMJD1C,EFNA3" MicroRNA hsa-miR-4326:mirSVR_highEffct hsa-miR-4326:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-22 6.39E-19 5.98E-22 5.49E-21 49 654 "LOC100128239,ZFYVE27,ACER3,SYT9,TMEM156,CHST15,FHL1,SLC30A10,ANXA7,PKP4,MAGI3,SLC2A5,RUFY2,LRRC55,ASPH,MEGF11,GABBR1,CAB39,GAD2,ARPP21,NCAM1,ALDH1L1,EML4,CAMK2G,GRIA2,DAAM2,MAEL,PADI2,MAGI1,NRXN1,CAMKV,BTF3L4,PRRX1,CNRIP1,ATRNL1,PKN2,ECE2,ZBTB16,GON4L,SYNC,MED24,SLC25A48,ZYG11B,RFX4,SEC61A2,GPR61,ARHGAP12,SLC4A10,ELAVL4" MicroRNA hsa-miR-1827:PITA hsa-miR-1827:PITA_TOP PITA 1.24E-22 6.72E-19 6.28E-22 5.76E-21 33 261 "SDE2,ASIC1,SYT9,LRRC7,SEMA6A,ELMOD1,ANK1,ANK3,CAPRIN2,RCOR3,EIF4G3,KIF21B,NMNAT2,GPR162,NCDN,FAM168A,ASTN2,CACNA1E,NRGN,CAMK2A,CAMK2G,PSD3,TIE1,CELF3,REPS2,TPM3,NRXN2,CCDC136,POU3F2,CTNND1,RAB5B,ST8SIA3,PIANP" MicroRNA hsa-miR-181a-2*:mirSVR_highEffct hsa-miR-181a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-22 6.75E-19 6.30E-22 5.78E-21 53 773 "SYT9,MDM4,CSMD3,GPR158,SCN3A,LRRC7,GOLGA7B,ELMOD1,SH3GL2,NTNG1,SLITRK3,ST3GAL3,BCAS1,ZNF365,SPHKAP,DDX25,RCOR3,ATM,ATP1A3,FXYD6,C11orf87,ZNF638,GNG4,SYT6,VSTM2A,GRIA1,GRIA2,ADAMTS8,TMEM257,REPS2,CDH8,PTGDR2,LGI1,UBTF,TJP2,SNCAIP,FEZ1,PRKAB2,MAPK8,EDRF1,NOS1AP,KIAA0513,GON4L,SPIRE1,MAGI2,KCNC1,NTM,TMEM255A,DPP6,ZYG11B,ZNF248,SEC61A2,RNF220" MicroRNA hsa-miR-379:mirSVR_lowEffct hsa-miR-379:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-22 6.79E-19 6.34E-22 5.81E-21 58 930 "TTYH1,TMEM74,CSMD3,KLHL32,GRAMD1B,AGT,SCN3A,LINC00461,FGF1,BBOX1,SFPQ,PPFIA1,ST8SIA1,SHANK2,ASCL1,ASTN1,ALDH4A1,SON,LMO3,SLCO1C1,NFIA,GLS,SYT4,CAMTA1,GPM6A,ACSL6,TCF7L2,GRM3,MFSD2A,KCNK10,PDE1C,PDE2A,CNRIP1,POU3F2,PPP2R5C,ATRNL1,MASP1,ZBTB16,CA10,PTHLH,PRDM2,LRP8,CSDE1,OLFM3,PLPPR4,KCNC1,DLG3,KIF2A,RALGDS,SLC25A18,DTNA,RET,RFX4,JMJD1C,PIANP,SH3GLB1,RAVER2,EPB41L2" MicroRNA hsa-miR-302b*:mirSVR_highEffct hsa-miR-302b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-22 7.06E-19 6.58E-22 6.03E-21 72 1417 "MDM4,KLHL32,SLITRK1,GALNT13,ERMN,SCN3A,LRRC7,SFPQ,CDC42BPA,ANK1,ANK2,ANK3,USP28,PPFIA1,DOCK10,SESN3,MAGI3,CCDC80,RUFY2,SHANK2,DACH2,SLIT1,ATP1A2,NRG3,PALLD,SON,AHCYL1,EMC1,SALL3,NCAM1,NDUFA5,ZNF638,DDHD2,NODAL,LRIT2,PTBP2,EML4,GRIA2,GRIA4,TLL2,ATG4C,PAX6,REPS2,TNS1,PCDH9,CIART,SLC25A27,PRRX1,CNRIP1,CP,POU3F2,CHD1L,PPP2R5C,SNCAIP,OSBPL3,VCAN,CTNND2,PROX1,DNAJC6,CADM2,PLPPR4,KCNK2,PCDH15,KCNMA1,DLG2,ABI1,DSCAM,ABCC9,JMJD1C,RGS7,CBLN2,RAVER2" MicroRNA hsa-miR-325:mirSVR_lowEffct hsa-miR-325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-22 7.06E-19 6.58E-22 6.03E-21 63 1097 "ACER3,FAM43B,MRVI1,F3,CLIP1,KLHL32,SLC44A5,FCGR1A,LINC00461,FGF14,ANXA7,APBA2,CACHD1,NLGN1,API5,DACH2,SLCO1A2,ASPH,SMARCE1,RCOR3,CCDC181,WDTC1,MYT1L,SOX5,B4GALNT1,FXYD6,GPR162,GLS,CASTOR3,PCDH11X,DDHD2,UNC5D,GPM6A,PTBP2,EML4,GRM3,SPX,TMEM25,P2RX7,TPD52,HMGB1,JAM2,CCSER2,CNTN1,CNRIP1,CHD1L,CRLS1,MICAL2,PRKACB,NRSN1,TOX,GON4L,PLPPR5,BLOC1S6,OLFM3,PCDH15,RALGDS,ATG16L1,ABCC9,ATL1,RPRD1A,OLIG2,LRRC23" MicroRNA hsa-miR-10b:mirSVR_lowEffct hsa-miR-10b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-22 7.92E-19 7.37E-22 6.76E-21 73 1457 "RABEPK,ZFYVE27,MBP,CSMD2,SORCS1,GRAMD1B,FOXRED2,NLGN4X,LRRTM4,DISP3,ANK1,ANK3,ZNF365,SFMBT2,URGCP,MSR1,LRRC55,SLC14A1,CGREF1,BRINP2,MYT1L,LHFPL4,KIF1B,SPART,ALDH1L1,ERBIN,RGL1,SEPT3,DDHD2,UNC5D,ATF7,ACSL6,NEU4,CAMK2G,AKNA,GRIK3,GRIK4,GRM3,TGFBR3,ZDHHC22,DAAM2,PRMT8,GPR37L1,HNRNPK,NEGR1,NMT2,A2ML1,OPALIN,TJP2,FTO,PLXNB3,ATCAY,MED1,FEZ1,EDRF1,PSD,GON4L,SPIRE1,BDNF-AS,ITIH2,CSDE1,CDH20,PTPRO,SRGAP3,FAM57B,GOPC,GNE,FAM135B,INSYN2,SSPN,GPR61,FGFBP3,UEVLD" MicroRNA hsa-miR-220c:mirSVR_highEffct hsa-miR-220c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-22 8.05E-19 7.48E-22 6.87E-21 53 776 "SYT9,ARID1A,MDM4,NLGN4X,LRRC7,FHL1,SH3GL2,BCAN,ST8SIA1,PAAF1,SLC8A3,MT3,NAXD,SORCS3,SNAP25,GABBR1,GJB1,SYT4,NKX2-2,KLHL4,ANO4,GPM6A,ZEB1,GRID1,GRIK2,TGFBR3,SEZ6L,PCSK2,PDE4B,GDAP1L1,A2ML1,FTO,SLC36A4,PTPA,RGS6,ATRNL1,RBPJ,USP54,CTNND1,PUM1,PTCH1,HP1BP3,OCIAD1,SMG7,KCND3,PTPRZ1,PEX5,DPP6,RFX5,SLC39A12,RPRD1A,ARHGAP12,SLC4A10" MicroRNA hsa-miR-205-5p:TargetScan hsa-miR-205-5p TargetScan 1.60E-22 8.68E-19 8.06E-22 7.39E-21 40 419 "RTN3,LDLRAD3,ARID1A,MDM4,FGF14,ANK2,PI16,NTNG1,MAGI3,SCMH1,PHYHIPL,JPH4,NEK6,KIF1B,FAM168A,NFIA,KAZN,PSD3,MAGI1,PDE3B,HMGB1,PFKFB3,HNRNPK,CADM1,ACBD5,MED1,CRMP1,MICAL2,PROX1,MAGI2,PTPRD,KCND3,DLG2,PHC2,RBM12,GPR61,ABI2,ELAVL4,EPB41,EPB41L1" MicroRNA hsa-miR-514:mirSVR_highEffct hsa-miR-514:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-22 9.14E-19 8.48E-22 7.78E-21 55 840 "EPS8,SLC25A25,RTN1,FABP7,SORCS1,ERMN,SCN3A,LRRTM4,TRIM46,USP28,DOCK10,SESN3,NTNG1,ZNF365,ARFGAP2,DACH2,NAXD,PHYHIPL,SON,GAD2,B4GALNT1,NPAS3,DCLK2,CAMSAP2,TCF12,GRIA2,GRIK2,GRIK4,PDE3B,ANO5,CADM1,CELF5,BTF3L4,SPATA6,FAAP20,ETNPPL,ATRNL1,NRSN1,PLPPR5,SYNC,LRRTM3,PTHLH,MAGI2,OCIAD1,SMG7,PTPRZ1,RABGAP1L,KCNJ11,KCNK2,SUSD4,ABI1,GNE,ABCC9,ELAVL4,BAALC" MicroRNA hsa-miR-208b:mirSVR_lowEffct hsa-miR-208b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-22 9.66E-19 8.95E-22 8.21E-21 55 841 "MEG3,ARID1A,F3,KLHL32,TESK2,SOX6,SH3GL2,APC,MAGI3,SYBU,PAAF1,ZNF365,RPH3A,ASCL1,SPHKAP,SMARCE1,ATP1A2,SON,SOX5,B4GALNT1,KIF1B,ADGRB2,NDUFA5,RGL1,PCDH11X,KAZN,PRUNE2,TCF12,PTBP2,VSTM2A,OMG,RBFOX2,PDE1A,CASC2,DNAJC12,MEAF6,NXPH1,ACBD5,RNF14,PPP3CB,RGS6,MAPK8,MAPK10,FAM131B,BRINP3,ANKS1B,CA10,CADM2,HP1BP3,PTPRO,KCNN3,SLC17A6,ABI1,SLC39A12,TMEM100" MicroRNA hsa-miR-3119:mirSVR_highEffct hsa-miR-3119:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.94E-22 1.05E-18 9.72E-22 8.91E-21 71 1390 "ACHE,TMEM74,FAM43B,ADARB2,PPM1E,APC,MAGI3,SHTN1,AQP4,MIER1,CCDC88A,PDE8B,SCG3,SMARCE1,RCOR3,ATM,MEGF11,USP33,SOX1,KIF1B,ZNF302,DCAF5,RGL1,ZNF638,GNAS,TCF7L2,CECR2,RFFL,TGFBR3,USP2,INA,GUCY1A2,ZFP91,ARHGAP19,TPD52,PCSK2,PDE1C,PIRT,PDYN,CASC2,HNRNPK,TLX1,GDAP1L1,CADM1,NRXN1,NOMO2,ANLN,PIK3CD,OPALIN,MED1,PPP3CB,PRKAB2,PUM1,ZNF385B,ITGAV,JAKMIP2,ITIH2,HP1BP3,LRP8,KCNMA1,DNAH9,RTN4,PAK5,RFX4,RGS7,SEC61A2,SSPN,PIANP,RPRD1A,SLC4A10,EPB41L2" MicroRNA hsa-miR-934:mirSVR_highEffct hsa-miR-934:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.07E-22 1.12E-18 1.04E-21 9.53E-21 46 578 "ACER3,MBP,WAC,SORCS1,TMEM156,LINC00461,KIAA1109,SLC30A10,CDC42BPA,ITSN1,BCAS1,ZNF365,SCG3,SPHKAP,ASPH,RCOR3,ZCCHC24,C11orf87,ZNF638,SYT4,DCLK2,PRLHR,MAGI1,PRMT8,GDAP1L1,SLC25A27,SPATA6,CRLS1,SNCAIP,VCAN,NCAN,RAB39A,GON4L,SYNC,PSMD13,CEP170,KCNJ10,KCNMA1,DLG3,GNE,DBX2,JMJD1C,INSYN2,SEC61A2,EFNA3,EPB41L1" MicroRNA hsa-miR-369-3p:PITA hsa-miR-369-3p:PITA_TOP PITA 2.45E-22 1.33E-18 1.22E-21 1.12E-20 45 553 "ACLY,EYA1,SLITRK1,GPR158,ELMOD1,FOXG1,NTNG1,CACHD1,ST3GAL3,BCAS1,SLC1A2,ARHGAP5,SNAP25,EIF4G3,FYN,SOX1,NEUROD1,ARHGEF7,GPM6A,CACNB2,ZEB1,TCF12,RFFL,PTPN5,GUCY1A2,TJP1,TLL2,RBFOX2,PDE4B,ZMYND8,TMEFF2,ANLN,PHACTR3,RBPJ,PRKAB2,FMN2,PTCH1,DNAJC6,RAB5B,GOPC,JMJD1C,PIANP,SLC4A10,EPB41,SEZ6" MicroRNA hsa-miR-4326:mirSVR_lowEffct hsa-miR-4326:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.46E-22 1.33E-18 1.23E-21 1.13E-20 79 1700 "RABEPK,SYNDIG1,KLRC4,SLC44A5,TOMM40L,SNX32,UNC79,MOBP,AMPH,APBA2,SESN3,NLGN1,ZNF365,MSR1,SLCO1A2,MTR,SORCS3,TMEM108,NRG3,EIF4G3,WDTC1,SLCO1C1,CASTOR3,ZNF638,DCLK2,TBX15,CACNA1A,VWC2,PRLHR,ZEB1,MFSD2A,TJP1,CELF3,CDC42,PCDH8,DCLK1,RBFOX2,ZNF384,IGFN1,PDYN,HMGB1,TMPRSS5,PFKFB3,HEPACAM,CADM1,KIAA1549L,C11orf49,NXPH1,CP,POU3F2,PPP2R5C,MICAL2,VCAN,PRKACB,DOCK7,RAB39A,PRKCZ,NOS1AP,MASP1,PHYHIP,DNAJC6,PRDM2,OCIAD1,SMG7,KCNH1,SRGAP3,KCNJ10,PCDH15,DLG2,WIPF2,FAM13C,RTN4,PAK5,SLC6A15,ARHGEF10L,SFXN5,ABI2,TMEM100,EPB41L1" MicroRNA hsa-miR-711:mirSVR_lowEffct hsa-miR-711:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-22 1.39E-18 1.28E-21 1.18E-20 65 1181 "TTYH1,RTN3,CSMD2,SLC25A25,ADARB2,NLGN4X,LRRC7,ASIC4,APBB1,ST3GAL3,ARFGAP2,ARFGAP1,NAXD,MTR,RCOR3,IGSF9B,WDTC1,KIF21B,ZSWIM8,ADAM15,NPAS3,NFASC,ERBIN,NELL1,PHLDB1,VAMP1,NKX2-2,MYRF,BTRC,CNDP1,CACNA1E,PRLHR,NUMA1,GRIA1,RFFL,GRIN1,TLL2,CELF3,ZDHHC22,PDYN,GPR37L1,GDAP1L1,CAMKV,NSD2,RGS6,FEZ1,NCAN,KLK6,ACY3,BDNF-AS,ELMO1,PRDM2,COPS7A,KCNA6,RABGAP1L,KCNMA1,CAB39L,OLIG1,DNM2,SLC25A18,RASGRF1,DTNA,RET,VANGL2,RAVER2" MicroRNA hsa-miR-1283:PITA hsa-miR-1283:PITA_TOP PITA 2.71E-22 1.47E-18 1.35E-21 1.24E-20 48 638 "WAC,SORCS1,NLGN4X,TESK2,SCN3A,LRRC7,UNC79,SOX6,PPM1E,SESN3,SLITRK3,CCDC88A,SNAP25,SOX1,MYT1L,SALL3,NCAM1,SMOC1,NFIA,CNTN2,GPM6A,TCF7L2,GRM3,RBFOX2,TPM3,CADM1,NEGR1,UBTF,PRRX1,FAT3,FMN2,PKN2,PUM1,KIAA0408,BRINP3,TOX,PTCH1,DNAJC6,HP1BP3,KCNA1,PTPRZ1,KCNK1,KCNMA1,DLG2,BSDC1,JMJD1C,RGS7,PHC2" MicroRNA hsa-miR-3129:mirSVR_lowEffct hsa-miR-3129:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.77E-22 1.50E-18 1.38E-21 1.27E-20 74 1511 "ZFYVE27,MAPT,SYT9,LGR4,FABP7,FCGR1A,SEMA6A,FHL1,FOXM1,TRIM46,ITSN1,NLGN1,LRRC4C,API5,PAAF1,MIER1,BCO1,CCDC88A,SLIT1,SORCS3,TNIK,ILDR2,TTLL9,SPART,NFASC,ALDH1L1,STOX1,ADHFE1,NEUROD1,SLCO1C1,GLS,SYT4,GNAS,ADGRL3,GOLGB1,PRUNE2,ZEB1,VXN,GRIA1,ATP13A2,TJP1,CELF3,REPS2,CDC42,ARHGAP19,PRMT8,TMPRSS5,CHRNB2,JAM2,HEPACAM,CCSER2,DNAJC12,BEST1,SPATA6,ACBD5,PPP3CB,MICAL2,PHACTR3,PRKACB,TOX,TOMM20,PRDM2,PLPPR4,PTPRO,KCNH1,AK5,KCNK1,PCDH15,NAV2,ABI1,PAK5,RFX4,ARHGEF10L,PIANP" MicroRNA hsa-miR-583:PITA hsa-miR-583:PITA_TOP PITA 2.97E-22 1.61E-18 1.48E-21 1.36E-20 38 378 "ASIC1,ARID1A,WAC,SORCS1,AMPH,APC,NTNG1,SLITRK3,SORBS1,NLGN1,FYN,SON,KIF21B,NPAS3,ERBIN,VAMP1,CACNA1E,REPS2,CDC42,RBFOX2,MAGI1,FNDC5,CADM1,NEGR1,ST8SIA5,SLC25A27,RIMS4,CA10,CEP170,KCNA1,SMG7,FAM135B,PHC2,EFNA3,ABI2,CBLN2,EN2,EPB41L2" MicroRNA hsa-miR-1237:mirSVR_highEffct hsa-miR-1237:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.99E-22 1.62E-18 1.49E-21 1.37E-20 54 819 "RABEPK,SYT9,ACTN2,ATAT1,LRRTM4,FGF1,BCAR3,FOXG1,SGIP1,ANK3,CNIH2,SORBS1,PAAF1,SLC8A3,SLC14A1,SPHKAP,SLN,SORCS3,ASTN1,EIF4G3,PHYHIPL,TNIK,ZCCHC24,KIF21B,JPH4,TTLL9,GLS,ZNF638,GNAS,DDHD2,CAMSAP2,ANO4,VWC2,CACNB2,TCF7L2,GRIK2,LGI1,FNDC5,CRLS1,TENM4,ZBTB16,PRDM2,CDH20,SMG7,PTPRE,PLPPR4,PTPRO,KCNK2,PCDH15,SUSD4,PAK5,SEC61A2,RBM12,ARHGAP12" MicroRNA hsa-miR-1:mirSVR_highEffct hsa-miR-1:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.03E-22 1.64E-18 1.51E-21 1.38E-20 66 1220 "RABEPK,ACER3,ADGRV1,ADAR,SLITRK1,CHST15,ASRGL1,ITSN1,APC,API5,ZNF365,MIER1,SLC6A9,DACH2,SCG3,ASPH,SORCS3,TMEM108,SNAP25,USP33,SOX5,ILDR2,GAD2,DNER,NPAS3,FGF17,NEUROD1,GLS,POPDC3,WWC1,ANO4,GPR17,GRM3,CDC42,SEZ6L,LGI1,TPM3,MAGI1,PIRT,HNRNPK,TMEFF2,GDAP1L1,CCSER2,C11orf49,NSD2,MED1,RNF14,PRKACB,PLPPR1,JAKMIP2,ELMO1,OCIAD1,SMG7,PLPPR4,KCNK2,KIF2A,SLC17A6,PARP11,SUSD4,SLC6A15,CRTAC1,RGS7,SYT15,SLC4A10,BSCL2,EN2" MicroRNA hsa-miR-1278:mirSVR_highEffct hsa-miR-1278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.16E-22 1.71E-18 1.57E-21 1.44E-20 54 820 "RTN3,EYA1,RTN1,WAC,SORCS1,SLC44A5,GPR158,MOBP,USP28,DOCK10,TACC2,PAAF1,CCDC88A,DACH2,CADPS,EIF4G3,PALLD,DKK3,NPAS3,CLASP2,ERBIN,NEUROD1,GLS,PCDH11X,SYT4,POPDC3,ADGRL3,TCF12,PTBP2,GRIA2,GRM3,TMEM257,CDC42,PDE3B,PDE4B,CELF5,SLC25A27,NSD2,POU3F2,RNF14,OSBPL3,RBPJ,PRKACB,CTNND2,EDRF1,ANKS1B,PLPPR5,LRRTM3,DNAJC6,ZC3H11A,KCNMA1,DTNA,ZNF248,CBLN2" MicroRNA hsa-miR-194*:mirSVR_highEffct hsa-miR-194*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-22 1.72E-18 1.58E-21 1.45E-20 47 612 "SERPINA3,ACLY,LGR4,MEG3,WLS,GRAMD1B,GPR158,ITSN1,CACHD1,PAAF1,CCDC88A,SPHKAP,SLN,ADGRB2,ZNF638,LRIT2,VSTM2A,GRIN1,AIFM1,ZFP91,CDC42,TPD52,JAM2,SEMA5B,PMP2,BEST1,ACBD5,CRMP1,SNCAIP,PRKACB,DZIP3,PLPP4,PRKCZ,IGSF1,ECE2,PRDM2,STMN4,OCIAD1,SV2A,HS3ST4,WIPF2,RAB5B,RFX4,SEC61A2,SLC4A10,YY1AP1,EPB41" MicroRNA hsa-miR-767-3p:mirSVR_highEffct hsa-miR-767-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.09E-22 2.21E-18 2.03E-21 1.86E-20 56 888 "ZFYVE27,SYT9,CSMD3,ADAR,ADORA3,AMER2,SNX32,LRRTM4,C1orf61,PPFIA1,DOCK10,TACC2,API5,PAAF1,CCDC88A,ASPH,ARPP21,NCAM1,ZNF302,ADHFE1,AJAP1,GLS,SYT4,CAMTA1,ANO4,CACNB2,ZEB1,PTBP2,CAMK2G,CECR2,GRIA4,GRID1,ATP13A2,PDE1A,PRMT8,PDYN,HPSE2,TJP2,ST8SIA5,SULT4A1,MICAL2,PROX1,TOX,PTCH1,DNAJC6,STMN4,KCNA4,SRGAP3,KIF2A,KLRC2,TMEM255A,ABCC9,SLC6A15,RBM12,EPB41L2,BAALC" MicroRNA hsa-miR-134:mirSVR_highEffct hsa-miR-134:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.72E-22 2.56E-18 2.34E-21 2.15E-20 50 705 "TMEM74,WLS,SORCS1,KIAA1109,FOXG1,AMPH,ITSN1,MAGI3,CACHD1,ST3GAL3,SLC8A3,SLC14A1,SMARCE1,GABBR1,ILDR2,KIF1B,NFASC,AJAP1,ACSBG1,PCDH11X,ANO4,NRDC,EML4,CECR2,GRIK2,TMEM9,MAEL,MAGI1,ZMYND8,JAM2,CADM1,A2ML1,BEST1,MFSD4A,SNCAIP,PRKCG,PLPP4,NRSN1,CADM2,CEP170,AK5,KCNK2,KCNMA1,DNAH9,SLC25A41,SUSD4,DSCAM,GNE,CRTAC1,SEC61A2" MicroRNA hsa-miR-409-5p:mirSVR_lowEffct hsa-miR-409-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.03E-22 2.73E-18 2.49E-21 2.28E-20 51 736 "SDE2,ACER3,SRARP,SYT9,KLHL32,RTN1,BCAR3,ELMOD1,FOXG1,SOX6,ANK3,SH3GL2,NTNG1,CCDC80,SYBU,RUFY2,DACH2,CADPS,TMEM249,CSPG5,SPHKAP,SMARCE1,SON,AHCYL1,KIF1B,NFASC,DCLK2,GPM6B,PTBP2,GPR88,GRM3,PAH,ZNF384,LRTM2,CASC2,TUB,TLX1,NRXN1,A2ML1,SLC36A4,MFSD4A,PTPA,OSBPL3,PKN2,TOX,ITGAV,PRDM2,KCNA1,SNX27,DBX2,CBLN2" MicroRNA hsa-miR-539:PITA hsa-miR-539:PITA_TOP PITA 5.03E-22 2.73E-18 2.49E-21 2.28E-20 42 483 "DSCAML1,ERMN,LRRC7,ELMOD1,AMPH,PPM1E,NTNG1,PKNOX2,FYN,MEGF11,SOX5,DNER,NCAM1,CLASP2,NFIA,PCDH11X,POPDC3,NKX2-2,CAMSAP2,BTRC,GPM6A,TCF7L2,TCF12,NUDT21,GRIA2,CELF3,HNRNPK,NLGN3,NMT2,SPATA6,MED1,SF1,CTNND1,CADM2,HP1BP3,OLFM3,SRGAP3,KCNK1,HS3ST4,SFXN5,RBM12,RCAN2" MicroRNA hsa-miR-452*:mirSVR_highEffct hsa-miR-452*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.22E-22 2.83E-18 2.58E-21 2.37E-20 69 1341 "C1orf194,ZFYVE27,SYNDIG1,MEG3,EYA1,MDM4,FABP7,TMEM156,MOBP,AMPH,ANK2,USP28,PPFIA1,PKP4,DOCK10,DGKD,NLGN1,BCAS1,SLC1A6,LRRC55,CGREF1,ASPH,TMEM108,AHCYL1,TTLL9,NCAM1,LMO3,SLCO1C1,ARHGEF7,ZNF638,ASTN2,GNAS,DDHD2,ANO4,GPM6B,CACNB2,B4GALNT4,ZEB1,NUMA1,INA,TMEM257,PAX6,PCDH9,PDE4B,BEST3,ZBED5,TMEFF2,PIK3CD,A2ML1,P2RY12,ATRNL1,PROX1,PLPPR5,SYNC,PSMD13,ITGAV,PTHLH,LRP8,PTPRD,PLPPR4,PCDH15,SLC25A48,RAD52,SUSD4,RTN4,ZYG11B,SEC61A2,ARHGAP12,RASGRP2" MicroRNA hsa-miR-205:mirSVR_highEffct hsa-miR-205:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.28E-22 2.86E-18 2.60E-21 2.39E-20 58 958 "RTN3,MDM4,CLIP1,TESK2,SCN3A,CCDC80,SORBS1,SLC2A5,ASPH,PHYHIPL,PALLD,JPH4,ARPP21,ZNF302,ZNF638,CAMSAP2,GOLGB1,WWC1,GPM6A,LILRA1,ZEB1,EML4,GRIA2,GRIA4,TPM4,MAGI1,ZNF384,PDE1C,PDE3B,MS4A7,HNRNPK,CADM1,C11orf49,PPP3CB,RGS6,KCNT2,MICAL2,ATRNL1,NCAN,PRKACB,PROX1,FGFR1OP2,ZBTB16,PSMD13,HP1BP3,OCIAD1,C1orf109,KCNMA1,CAB39L,SLC25A48,GNE,SLC6A15,PHC2,RBM12,ABI2,RAVER2,EPB41,RCAN2" MicroRNA hsa-miR-581:mirSVR_highEffct hsa-miR-581:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.32E-22 2.88E-18 2.62E-21 2.41E-20 56 893 "LGR4,CSMD2,ADCY2,FABP7,LRRTM4,LINC00461,PPFIA1,DGKD,TACC2,SHTN1,ZNF365,MIER1,DACH2,ASPH,BRINP2,ATM,EIF4G3,PALLD,SON,MYT1L,TTLL9,NDUFA5,KIRREL3,BTRC,CACNB2,VSTM2A,GRIA1,CCKBR,PAH,PCDH9,BEST3,TMEFF2,JAM2,OPALIN,MEAF6,TENM4,NCAN,RAB39A,MAPK10,KIAA0513,ZNF385B,KCNA2,PTPRD,KCNC1,PTPRO,RABGAP1L,KCNJ10,TMCC2,KCNK1,KCNMA1,CAB39L,DSCAM,INSYN2,VWA5A,ELAVL3,RCAN2" MicroRNA hsa-miR-3117:mirSVR_lowEffct hsa-miR-3117:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.37E-22 2.91E-18 2.65E-21 2.43E-20 60 1025 "ACER3,MBP,ACTN2,SLC25A25,CSMD3,FABP7,SNX32,FGR,SELL,ERICH3,SGIP1,CDC42BPA,ST8SIA1,MSR1,CCDC88A,CADPS,ASPH,B3GAT1,DKK3,USP33,ARPP21,KIF1B,NPAS3,NDUFA5,SMOC1,ARHGEF7,UNC5D,ANO4,ATF7,SYT6,GPR88,CRB1,TGFBR3,DCLK1,RBFOX2,MAGI1,PDE3B,LINC01102,HNRNPK,CADM1,CCSER2,FTO,CNTN1,COL9A2,ACBD5,PRKAB2,DOCK7,MASP1,TOX,JAKMIP2,CEP170,OCIAD1,RAB5B,SLC25A18,L1CAM,RBM12,CBLN2,SLC4A10,ELAVL3,SEZ6" MicroRNA hsa-miR-374b*:mirSVR_highEffct hsa-miR-374b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.51E-22 2.98E-18 2.71E-21 2.49E-20 59 992 "ACER3,SYT9,WLS,CSMD3,BCAR3,ELMOD1,APC,NTNG1,CCDC80,PAAF1,CCDC88A,SCG3,KBTBD12,NRG3,SON,CAB39,ILDR2,NEK6,GART,NPAS3,ALDH1L1,SLCO1C1,GNAS,CAMTA1,CAMSAP2,ADGRL3,ACSL6,CACNA1E,CACNB2,PTBP2,EML4,VXN,PAX6,HPS5,CDH10,MAGI1,CCSER2,CP,DOCK7,PLD5,PROX1,CADM2,COPS7A,STMN4,PTPRD,PTPRE,PLPPR4,CAB39L,KIF2A,TMEM255A,RASGRF1,DTNA,PAK5,INSYN2,PIANP,RPRD1A,OLIG2,TMEM100,BAALC" MicroRNA hsa-miR-18a*:mirSVR_highEffct hsa-miR-18a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.52E-22 2.99E-18 2.71E-21 2.49E-20 49 678 "RCSD1,ACTN2,NDRG2,HOGA1,SOX6,ITSN1,NTNG1,DGKZ,SORBS1,RCOR3,B3GAT1,ATM,SON,B3GALT2,ENKUR,ALDH1L1,DCAF5,ASTN2,ANO4,GRIA4,RFFL,LINC00839,INA,AIFM1,PADI2,LILRA4,FNDC5,HEPACAM,GDAP1L1,CADM1,CAMKV,PRRX1,SNCAIP,PPP3CB,MICAL2,NCAN,MASP1,BDNF-AS,COPS7A,CDH20,KCNC1,KCNK2,CAB39L,PID1,SLC6A15,ARHGEF10L,PHC2,ABI2,RAVER2" MicroRNA hsa-miR-139-5p:mirSVR_highEffct hsa-miR-139-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.91E-22 3.20E-18 2.90E-21 2.67E-20 56 895 "ACLY,SYT9,MRVI1,WLS,NDRG2,KLHL32,ERMN,SCN3A,KIAA1109,LRRC7,ANK2,RASA3,PKP4,WDTC1,SOX1,SOX5,KIF1B,DNER,ZNF302,ERBIN,AJAP1,PCDH11X,ZNF638,SYT4,GPM6A,NPPA,ZEB1,GPR17,TCF12,PCDHGA3,AKNA,GRIK2,CDC42,TPD52,MAGI1,ADGRG1,A2ML1,P2RY12,NXPH1,PPP3CB,TOX,ANKS1B,SPIRE1,HP1BP3,PTPRD,PTPRZ1,PCDH15,KCNMA1,PEX5,RASGRF1,RTN4,PAK5,NUP214,JMJD1C,RLBP1,RPRD1A" MicroRNA hsa-miR-340-5p:TargetScan hsa-miR-340-5p TargetScan 6.07E-22 3.29E-18 2.98E-21 2.74E-20 59 994 "ABAT,CSMD3,F3,PLEKHG5,GALNT13,AMER2,FGR,CDC42BPA,MAGI3,GAS7,DGKD,LRRC55,PKNOX2,NSG2,SCMH1,B3GAT1,CADM3,NEK6,BCL2L2,DCAF5,NHLH1,POPDC3,LUZP2,DDHD2,CAMSAP2,CAMK2A,DDR2,BRSK2,PSD3,GRID1,RFFL,PTPN5,FBXL16,DAAM2,RBFOX2,HMGB1,NEGR1,FTO,FAT3,MICAL2,SDC3,PLD5,PUM1,FAM131B,PROX1,KIAA0408,JAKMIP2,LRP8,KCNA4,KCNK1,NKAIN1,KIF2A,CALN1,GOPC,DSCAM,RPRD1A,ELAVL3,ELAVL4,EN2" MicroRNA hsa-miR-579:PITA hsa-miR-579:PITA_TOP PITA 6.36E-22 3.44E-18 3.12E-21 2.86E-20 40 435 "MAPT,CSMD3,ADARB2,DSCAML1,SNX30,SCN3A,SOX6,PKP4,APC,NTNG1,GPAM,NLGN1,LRRC4C,CADPS,SOX5,ZCCHC24,NPAS3,ERBIN,GNAS,TMEM257,KCNK10,CDC42,CDH10,LGI1,FAT3,POU3F2,MED1,PKN2,CTNND1,CADM2,CSDE1,KCNA1,KCNA4,PTPRD,DLG2,TMEM255A,CALN1,GOPC,ABI2,EPB41L2" MicroRNA hsa-miR-2278:mirSVR_highEffct hsa-miR-2278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.83E-22 3.70E-18 3.34E-21 3.07E-20 60 1030 "RABEPK,LDLRAD3,CSMD2,HOGA1,SCN3A,KIAA1109,DISP3,LRRC7,FHL1,BBOX1,SLC30A10,CNIH2,PPM1E,APC,DACH2,CAPRIN2,ASPH,DKK3,NFASC,GFAP,ADHFE1,NHLH1,DCLK2,GNAS,CNTN2,ADGRL3,GOLGB1,ZEB1,PTBP2,GRIA2,CYB561A3,ZFP91,PAX6,TNR,HERC2P3,TMEFF2,NRXN1,CAMKV,PRRX1,NXPH1,PPP2R5C,SNCAIP,RGS6,MICAL2,RBPJ,PRKACB,USP54,FAM131B,PSD,SYNC,CSDE1,PTPRE,KCNC1,WIPF2,SLC17A6,ZYG11B,RET,USH1C,EFNA3,RPRD1A" MicroRNA hsa-miR-221:mirSVR_highEffct hsa-miR-221:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.83E-22 3.70E-18 3.34E-21 3.07E-20 60 1030 "ARID1A,CSMD3,ERMN,KIAA1109,ANK3,PPFIA1,NTNG1,SYBU,MIER1,LRRC55,CCDC88A,SHANK2,CAPRIN2,ASPH,MYT1L,SOX10,NAP1L2,SPART,C11orf87,ZNF302,ADHFE1,GLS,LUZP2,DDHD2,CAMTA1,GPM6A,CACNB2,GPR17,TCF12,DIRAS1,PTBP2,GRIA4,INA,MAEL,TPM3,MAGI1,PDE4B,CADM1,NXPH1,MED1,PPP3CB,RGS6,PLD5,PRKCZ,MAPK10,BRINP3,TOX,DNAJC6,PLPPR1,CADM2,PRDM2,KCNK2,SLC17A6,GOPC,PAK5,ABCC9,ATL1,SEC61A2,SLC4A10,BAALC" MicroRNA hsa-miR-214:mirSVR_highEffct hsa-miR-214:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.68E-22 4.16E-18 3.76E-21 3.45E-20 56 900 "ACER3,MAP6,ACLY,RCSD1,KLHL32,WAC,SORCS1,SCN3A,FGF1,LRRC7,FGF14,FHL1,ANK3,NTNG1,ST3GAL3,CLSTN1,ZNF365,MT3,ASTN1,ATM,MYT1L,ARPP21,NPAS3,GPR162,RGL1,ZNF638,DDR1,CACNB2,PTBP2,GRIK2,PTPN5,PAH,MAEL,TPM3,NOMO2,FTO,MEAF6,P2RY12,MFSD4A,ATRNL1,PHACTR3,CMTM5,PUM1,EDRF1,ANKS1B,SPIRE1,JAKMIP2,BDNF-AS,PTHLH,PRDM2,SRGAP3,KLRC2,PID1,TMEM255A,ZNF248,SLC4A10" MicroRNA hsa-miR-659:mirSVR_highEffct hsa-miR-659:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.88E-22 4.27E-18 3.85E-21 3.54E-20 60 1033 "SYT9,IL17D,RTKN,KLHL32,SLITRK1,TMEM156,FGF14,UNC79,MOBP,ANK3,NLGN1,SCMH1,SLN,DDX25,B3GALT2,ARPP21,TTLL9,KIF1B,SPART,NFASC,GANAB,SLCO1C1,PCDH11X,GNAS,ADGRL3,TCF7L2,TCF12,GRIA4,GPR88,CYB561A3,CDC42,CDH8,LGI1,TPM3,PRMT8,BEST3,ZBED5,NEGR1,CABP1,CELF5,SPATA6,PPP3CB,KCNT2,FEZ2,PRKACB,CTNND1,ECE2,TUBB2B,DNAJC6,JAKMIP2,MAGI2,RABGAP1L,KCNMA1,KCNN3,ABI1,GOPC,DTNA,PAK5,SLC4A10,UEVLD" MicroRNA hsa-miR-218-1*:mirSVR_lowEffct hsa-miR-218-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.10E-22 4.38E-18 3.95E-21 3.63E-20 71 1426 "PAQR6,ATAT1,LDLRAD3,SLC25A25,KLHL32,SLITRK1,SNX30,AGT,SLC30A10,ITSN1,DGKD,ST3GAL3,PKNOX2,DNAH17,BRINP2,NRG3,WDTC1,AHCYL1,CPLX2,BCL2L2,DCAF5,PHLDB1,ARHGEF7,CASTOR3,PCDH11X,KAZN,UNC5D,CNTN2,TMEM136,CACNA1A,PRUNE2,TCF7L2,ZEB1,VXN,NUCB1,GRIA4,CYB561A3,TGFBR3,P2RX7,CDK11B,CDC42,TPD52,TPM3,PRMT8,PDYN,NTSR2,CASC2,OPALIN,PMP2,CABP1,PRRX1,CRLS1,KCNT2,FEZ2,VCAN,PRKACB,FMN2,PKN2,USP54,ECE2,SIRPA,ITIH2,PLEKHB2,RALGDS,ABI1,DTNA,SYT15,EFNA3,RPRD1A,ABI2,YY1AP1" MicroRNA hsa-miR-889:mirSVR_highEffct hsa-miR-889:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.72E-22 4.72E-18 4.25E-21 3.90E-20 68 1317 "SDE2,RPL38,ADGRV1,ADORA3,LINC00461,KIAA1109,BCAR3,MOBP,SELL,ERICH3,DOCK10,NTNG1,MAGI3,CCDC80,MSR1,CCDC88A,SLC14A1,DACH2,SORCS3,USP33,B3GALT2,JPH4,ARPP21,C11orf87,DCAF5,GLS,ASTN2,LUZP2,CAMSAP2,TBX15,PTBP2,TGFBR3,TNS1,PCDH9,LGI1,ADGRG1,TMEFF2,CADM1,NEGR1,BTF3L4,SLC36A4,POU3F2,PPP3CB,OSBPL3,ATRNL1,PRKACB,PRKCZ,NRSN1,KIAA0408,FGFR1OP2,ITGAV,PTHLH,HP1BP3,BLOC1S6,PTPRD,PCDH15,KCNMA1,NAV2,DLG2,SLC17A6,PLEKHB2,ABI1,DSCAM,FAM13C,ABCC9,JMJD1C,TTLL7,ARHGAP12" MicroRNA "TGAATGT,MIR-181A:MSigDB" "TGAATGT,MIR-181A:MSigDB" MSigDB 9.34E-22 5.06E-18 4.54E-21 4.17E-20 41 465 "MAPT,CNTNAP3,SLC25A25,SLITRK1,SOX6,CDC42BPA,DOCK10,PKNOX2,ATP2B2,PALLD,USP33,MYBPC1,SOX5,MIR4697HG,LMO3,SEPT3,ARHGEF7,GLS,CACNB2,CAMK2G,GRIA2,GRIK2,KCNK10,NRXN1,NEGR1,NMT2,CCSER2,MEAF6,OSBPL3,DOCK7,PUM1,TOX,SPIRE1,RGMA,ZC3H11A,PLPPR4,ARNT2,KCNMA1,PAK5,LMO1,EN2" MicroRNA "TGAATGT,MIR-181C:MSigDB" "TGAATGT,MIR-181C:MSigDB" MSigDB 9.34E-22 5.06E-18 4.54E-21 4.17E-20 41 465 "MAPT,CNTNAP3,SLC25A25,SLITRK1,SOX6,CDC42BPA,DOCK10,PKNOX2,ATP2B2,PALLD,USP33,MYBPC1,SOX5,MIR4697HG,LMO3,SEPT3,ARHGEF7,GLS,CACNB2,CAMK2G,GRIA2,GRIK2,KCNK10,NRXN1,NEGR1,NMT2,CCSER2,MEAF6,OSBPL3,DOCK7,PUM1,TOX,SPIRE1,RGMA,ZC3H11A,PLPPR4,ARNT2,KCNMA1,PAK5,LMO1,EN2" MicroRNA "TGAATGT,MIR-181B:MSigDB" "TGAATGT,MIR-181B:MSigDB" MSigDB 9.34E-22 5.06E-18 4.54E-21 4.17E-20 41 465 "MAPT,CNTNAP3,SLC25A25,SLITRK1,SOX6,CDC42BPA,DOCK10,PKNOX2,ATP2B2,PALLD,USP33,MYBPC1,SOX5,MIR4697HG,LMO3,SEPT3,ARHGEF7,GLS,CACNB2,CAMK2G,GRIA2,GRIK2,KCNK10,NRXN1,NEGR1,NMT2,CCSER2,MEAF6,OSBPL3,DOCK7,PUM1,TOX,SPIRE1,RGMA,ZC3H11A,PLPPR4,ARNT2,KCNMA1,PAK5,LMO1,EN2" MicroRNA "TGAATGT,MIR-181D:MSigDB" "TGAATGT,MIR-181D:MSigDB" MSigDB 9.34E-22 5.06E-18 4.54E-21 4.17E-20 41 465 "MAPT,CNTNAP3,SLC25A25,SLITRK1,SOX6,CDC42BPA,DOCK10,PKNOX2,ATP2B2,PALLD,USP33,MYBPC1,SOX5,MIR4697HG,LMO3,SEPT3,ARHGEF7,GLS,CACNB2,CAMK2G,GRIA2,GRIK2,KCNK10,NRXN1,NEGR1,NMT2,CCSER2,MEAF6,OSBPL3,DOCK7,PUM1,TOX,SPIRE1,RGMA,ZC3H11A,PLPPR4,ARNT2,KCNMA1,PAK5,LMO1,EN2" MicroRNA hsa-miR-1261:mirSVR_highEffct hsa-miR-1261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.89E-22 5.36E-18 4.80E-21 4.41E-20 59 1004 "ACER3,TMEM74,ACTN2,EYA1,ADAR,WAC,AMER2,FOXM1,SELL,SGIP1,NTNG1,MIER1,MSR1,ARHGAP5,CCDC88A,ASTN1,TMEM108,EIF4G3,AHCYL1,KIF1B,ERBIN,SEPT3,GLS,SYT4,CDK5R2,KLHL4,ZEB1,PTBP2,GRIA4,CRB1,P2RX7,PAH,DAAM2,RBFOX2,FNDC5,CASC2,NRXN1,NEGR1,TJP2,PMP2,SLC36A4,NSD2,OSBPL3,VCAN,PRKAB2,USP54,EDRF1,GON4L,PTHLH,MAGI2,PTPRD,PTPRZ1,RABGAP1L,PCDH15,SLC6A15,SEC61A2,RPRD1A,CBLN2,C2orf80" MicroRNA hsa-miR-4280:mirSVR_highEffct hsa-miR-4280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-21 5.50E-18 4.92E-21 4.52E-20 46 601 "TTYH1,SYT9,AMER2,LRRTM4,MOBP,MOG,ST3GAL3,BCAS1,CCDC88A,ASPH,ASTN1,SMARCE1,ALDH4A1,GABBR1,AHCYL1,DNER,RAP1GAP2,NELL1,ARHGEF7,OS9,GNAS,ADGRL3,ATF7,VWC2,CACNB2,TCF12,GRIA1,PTPN5,PLEKHB1,NEGR1,SLC25A27,BEST1,NXPH1,FEZ2,PRKACB,DZIP3,WBP1L,ANKS1B,TOMM20,LRRTM3,JAKMIP2,KCNA4,DBX2,DTNA,ZNF248,RPE65" MicroRNA hsa-miR-2116:mirSVR_highEffct hsa-miR-2116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-21 5.77E-18 5.17E-21 4.74E-20 64 1178 "CNTNAP3,ARID1A,CLIP1,GALNT13,ADD3,ERMN,GRAMD1B,AGT,KIAA1109,FGF14,UNC79,PPFIA1,ANXA7,CCDC88A,DACH2,PDE8B,ASPH,SMARCE1,EIF4G3,PALLD,MYT1L,B3GALT2,TNIK,CAB39,GAD2,EMC1,IDI2-AS1,DNER,ARHGEF7,SEMA4A,CAMSAP2,ADGRL3,ZEB1,CLEC9A,GRIA2,OLR1,TMEM25,LEFTY2,TMEM257,ATG4C,PADI2,HMGB1,CASC2,A2ML1,CCDC136,SLC25A27,SLC36A4,ACBD5,CHD1L,MED1,FEZ2,OSBPL3,FMN2,RAB39A,TOX,JAKMIP2,KCNA4,PTPRO,C1orf109,PCDH15,DNM2,SLC17A6,RBM12,RPRD1A" MicroRNA hsa-miR-1282:mirSVR_lowEffct hsa-miR-1282:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-21 6.30E-18 5.64E-21 5.17E-20 49 690 "GALNT13,ANK1,ANK3,NTNG1,CCDC80,NSG2,SLIT1,ADGRA1,EIF4G3,SON,SOX5,GAD2,GFRA1,PHLDB1,SLCO1C1,GNAS,ADGRL3,PRUNE2,NRGN,VSTM2A,GRIA2,GRIK4,ADAMTS8,CRB1,TGFBR3,PAH,PCDH8,PCDH9,LGI1,ZNF384,ZBED5,CPT1C,CELF5,SLC36A4,NXPH1,ACBD5,ETNPPL,RGS6,RAB39A,IGSF1,TOX,CSDE1,KCNA4,KCNN3,DTNA,PAK5,SLC6A15,RFX4,SLC39A12" MicroRNA hsa-miR-943:mirSVR_highEffct hsa-miR-943:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-21 6.34E-18 5.67E-21 5.20E-20 50 720 "CSMD2,LRRC7,HPCAL4,USP28,NTNG1,ASCL1,SMARCE1,B3GALT2,ILDR2,RGL1,PCDH11X,ZNF638,PSRC1,TCF12,GRIK2,GPR88,CRB1,ZFP91,MAEL,MAGI1,HNRNPK,JAM2,NEGR1,A2ML1,ST8SIA5,PMP2,PRRX1,ACBD5,PLD5,PUM1,FGFR1OP2,BRINP3,TOX,PSMD13,DNAJC6,PRTFDC1,COPS7A,CEP170,OLFM3,PLPPR4,KLRC2,PID1,SLC25A18,DTNA,CAMK1G,RFX4,RGS7,INSYN2,RPRD1A,SLC4A10" MicroRNA hsa-miR-1226*:mirSVR_highEffct hsa-miR-1226*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-21 7.58E-18 6.77E-21 6.21E-20 50 723 "RTN3,ATAT1,ADD3,SORCS1,ADORA3,TESK2,TRIM46,AMPH,ITSN1,SH3GL2,ZNF365,LRRC55,CGREF1,CAPRIN2,BRINP2,SORCS3,SMARCE1,RCOR3,NRG3,EIF4G3,FYN,KIF21B,GAD2,NPAS3,COLGALT2,ADHFE1,GLS,UNC5D,DDR1,NUMA1,GRIA2,GRIA4,CCKBR,C1orf94,PDYN,FNDC5,DUSP26,SEMA5B,CP,SNCAIP,FEZ1,PLPP4,BLOC1S6,OCIAD1,KCNK1,KCNMA1,DTNA,VWA5A,ARHGAP12,SEZ6" MicroRNA hsa-miR-93*:mirSVR_highEffct hsa-miR-93*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-21 7.72E-18 6.88E-21 6.32E-20 58 978 "TTYH1,MBP,ACTN2,ATAT1,ARID1A,MDM4,KLHL32,ADD3,NLGN4X,FCGR1A,MOBP,ANK3,ITSN1,NTNG1,ZCCHC17,CACHD1,MIER1,NAXD,CAPRIN2,SORCS3,ASTN1,SMARCE1,USP33,SOX5,ZSWIM8,ALDH1L1,RGL1,PHLDB1,NEUROD1,ARHGEF7,ZNF638,DDHD2,CACNA1E,CACNB2,ZEB1,PTBP2,GRIA2,GRIA4,AIFM1,CELF3,TNS1,ZMYND8,CHGA,A2ML1,CTNND2,FGFR1OP2,ANKS1B,TOMM20,PLPPR5,PTHLH,CADM2,KCNJ10,KCNK2,DLG2,TMEM255A,ZYG11B,ATL1,ZNF248" MicroRNA hsa-miR-663:mirSVR_lowEffct hsa-miR-663:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-21 7.80E-18 6.95E-21 6.38E-20 53 816 "DPF1,RABEPK,ACHE,SYT9,EXTL1,ATAT1,CLIP1,SLITRK1,ADORA1,AMER2,PLA2G6,TRIM46,CNIH2,ITSN1,DGKD,BCAN,CLSTN1,MIER1,SLC1A7,MADD,SLC6A9,KBTBD12,ADGRA1,SNCB,SOX1,KIF21B,SOX10,ADAM15,ADGRB2,RAP1GAP2,C11orf87,ALDH1L1,NCDN,RCOR2,TBX15,ATF7,CACNA1E,PTBP2,NUCB1,CYB561A3,SPX,TMEM25,FBXL16,HRH3,HPSE2,ASIC3,GDAP1L1,MICAL2,PRKCG,DPYSL5,KCNJ11,SUSD4,RNF220" MicroRNA hsa-miR-1261:mirSVR_lowEffct hsa-miR-1261:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-21 8.38E-18 7.45E-21 6.84E-20 69 1368 "TTYH1,RTN3,SYNDIG1,LDLRAD3,CSMD3,SLITRK1,GALNT13,CDC7,ADORA3,TOMM40L,FGF14,BCAR3,ANK3,PPFIA1,MAGI3,GPAM,CACHD1,AQP4,ZNF365,DACH2,ATM,PHYHIPL,ATP2B2,GABBR1,USP33,SON,ILDR2,ARPP21,COLGALT2,ALDH1L1,SMOC1,PSRC1,CNTN2,LRIT2,PTPN5,KCNK10,HPS5,PCDH9,PDE3B,BEST3,CHGA,KIAA1549L,A2ML1,CCSER2,FTO,PRRX1,POU3F2,CRLS1,PPP2R5C,ATRNL1,NCAN,PHACTR3,NRSN1,KIAA0408,CEP170,BLOC1S6,OLFM3,C1orf109,KCNJ10,KLRC2,PID1,TMEM255A,SLC17A6,DPP6,FAM13C,DBX2,SSPN,SLC4A10,YY1AP1" MicroRNA hsa-miR-595:mirSVR_highEffct hsa-miR-595:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-21 8.38E-18 7.45E-21 6.84E-20 52 786 "SYT9,ADGRV1,CSMD3,BCAR3,MOBP,MOG,SH3GL2,CACHD1,SYBU,SLC1A6,CCDC88A,SORCS3,SMARCE1,B3GALT2,ARPP21,NCAM1,AJAP1,GLS,CACNB2,GPR88,TGFBR3,INA,ZFP91,PAH,C1orf94,LGI1,TPM4,PRMT8,ANLN,UBTF,A2ML1,ST8SIA5,PRRX1,NSD2,NXPH1,RGS6,MICAL2,PHACTR3,PLD5,MAPK10,PUM1,PTHLH,KCNC1,SLC25A48,FAM66C,ATG16L1,ABCC9,ZYG11B,RGS7,ZNF248,RBM12,SLC4A10" MicroRNA hsa-miR-381-3p:TargetScan hsa-miR-381-3p TargetScan 1.62E-21 8.78E-18 7.81E-21 7.16E-20 46 608 "EPS8,F3,AMER2,FGF1,CDC42BPA,ANK3,APC,DGKD,EIF4G3,FYN,DKK3,KIF1B,NASP,NFASC,LMO3,GFRA1,NEUROD1,NFIA,GLS,ANO4,CECR2,DDR2,PSD3,AKNA,GRIA1,RFFL,PCDH8,RBFOX2,PCSK2,MAGI1,PDE1C,HMGB1,PFKFB3,CADM1,NRXN1,BTF3L4,FAT3,ACBD5,OSBPL3,RBPJ,KIAA0408,KCNH1,RPRD1A,EPB41,EPB41L1,RCAN2" MicroRNA hsa-miR-513a-5p:mirSVR_highEffct hsa-miR-513a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-21 9.52E-18 8.46E-21 7.76E-20 57 949 "EPS8,ADGRV1,EYA1,ADD3,TESK2,LRRC7,FGF14,MOBP,ERICH3,ANK3,PPFIA1,SFMBT2,SNAP25,NPAS3,ARHGEF7,ZNF638,NKX2-2,NODAL,UNC5D,PSRC1,ADGRL3,KLHL4,LILRA1,USP2,TIE1,PCDH9,PRMT8,JAM2,GDAP1L1,NRXN1,A2ML1,DNAJC12,C11orf49,MEAF6,SLC36A4,NSD2,POU3F2,ATRNL1,CTNND1,NRSN1,MASP1,WBP1L,DPYSL5,PLPPR5,JAKMIP2,CNIH3,MAGI2,PEX5,DLG2,C12orf4,GNE,DTNA,JMJD1C,CBLN2,PRRT4,EPB41L2,BAALC" MicroRNA hsa-miR-296-5p:mirSVR_lowEffct hsa-miR-296-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-21 1.00E-17 8.88E-21 8.15E-20 59 1017 "SERPINA3,ACER3,MEG3,PLEKHG5,SNX32,DISP3,APBB1,SLC1A7,SLC2A5,SLC6A9,SCMH1,IGSF9B,WDTC1,B3GALT2,KIF21B,ZSWIM8,TTLL9,ADGRB2,NCAM1,C11orf87,ALDH1L1,AJAP1,LUZP2,GNAS,WSCD1,CACNA1E,LRIT2,DIRAS1,NUMA1,GRIA1,GRIN1,TMEM25,TGFBR3,GUCY1A1,NEURL1,ZFP91,HRH3,PRMT8,GPR37L1,ST8SIA5,PLXNB3,NSD2,PTPA,ARHGEF4,MASP1,SIRPA,PRDM2,RGMA,KCNA1,KCNA6,SV2A,SRGAP3,NKAIN1,FAM57B,RASGRF1,ARHGEF10L,SIDT2,ELAVL3,SEZ6" MicroRNA hsa-miR-574-5p:mirSVR_highEffct hsa-miR-574-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-21 1.17E-17 1.04E-20 9.55E-20 51 761 "ATAT1,MOG,ERICH3,SLITRK3,SLC1A6,SLC1A7,MSR1,ARFGAP2,SLC14A1,LGI3,SMARCE1,SNAP25,ATM,GABBR1,AHCYL1,TTLL9,ADAM15,ADGRB2,NCAM1,RGL1,GNAS,ANO4,CACNA1A,CACNB2,NRGN,PTBP2,OLR1,HPSE2,CASC2,MS4A7,SEMA5B,DNAJC12,NSD2,MICAL2,CTNND2,MASP1,KIAA0513,CA10,BDNF-AS,PRTFDC1,ZC3H11A,KCNA2,PYGM,RAB5B,PID1,CAMK1G,RFX4,RERGL,CBLN2,RAVER2,EPB41L1" MicroRNA hsa-miR-3118:mirSVR_highEffct hsa-miR-3118:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.23E-21 1.21E-17 1.07E-20 9.82E-20 53 824 "TMEM74,WLS,SORCS1,KIAA1109,AMPH,ITSN1,MAGI3,CACHD1,ST3GAL3,SLC14A1,CAPRIN2,ASPH,SMARCE1,GABBR1,CAB39,ILDR2,KIF1B,NPAS3,NFASC,AJAP1,ACSBG1,PCDH11X,ANO4,NRDC,EML4,CECR2,GRIK2,TMEM9,PCDH9,MAGI1,ZMYND8,TMEFF2,JAM2,CADM1,A2ML1,BEST1,MFSD4A,SNCAIP,FMN2,PRKCG,LRP8,CEP170,KCNC1,AK5,KCNK2,KCNMA1,DNAH9,SUSD4,DSCAM,GNE,CRTAC1,ATL1,SEC61A2" MicroRNA hsa-miR-516b*:mirSVR_highEffct hsa-miR-516b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-21 1.28E-17 1.14E-20 1.04E-19 54 857 "RABEPK,ACER3,SYT9,LDLRAD3,F3,KLHL32,SLITRK1,GALNT13,SORCS1,HOGA1,SFPQ,PPFIA1,SH3GL2,MAGI3,SLITRK3,ZNF365,CCDC88A,SMARCE1,ATP1A2,MYT1L,KIF1B,NFASC,NCAM1,STOX1,HEPN1,ZNF638,SYT4,ASTN2,MMD2,GOLGB1,GPM6B,PRLHR,ZEB1,VSTM2A,GRIA2,GRIA4,OLR1,TMEM9,TNR,PDE1A,PDE4B,LINC01102,CRLS1,PPP2R5C,KCNT2,DZIP3,USP54,ZNF385B,PTPRE,PCDH15,PLEKHB2,PARP11,DPP6,DTNA" MicroRNA hsa-miR-516a-3p:mirSVR_highEffct hsa-miR-516a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-21 1.28E-17 1.14E-20 1.04E-19 54 857 "RABEPK,ACER3,SYT9,LDLRAD3,F3,KLHL32,SLITRK1,GALNT13,SORCS1,HOGA1,SFPQ,PPFIA1,SH3GL2,MAGI3,SLITRK3,ZNF365,CCDC88A,SMARCE1,ATP1A2,MYT1L,KIF1B,NFASC,NCAM1,STOX1,HEPN1,ZNF638,SYT4,ASTN2,MMD2,GOLGB1,GPM6B,PRLHR,ZEB1,VSTM2A,GRIA2,GRIA4,OLR1,TMEM9,TNR,PDE1A,PDE4B,LINC01102,CRLS1,PPP2R5C,KCNT2,DZIP3,USP54,ZNF385B,PTPRE,PCDH15,PLEKHB2,PARP11,DPP6,DTNA" MicroRNA hsa-miR-106b-5p:Functional MTI Functional MTI miRTarbase 2.38E-21 1.29E-17 1.14E-20 1.04E-19 61 1091 "ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,APC,GPAM,DGKD,SHTN1,USP16,RUFY2,CAPRIN2,MTR,FYN,GABBR1,SON,EMC1,SALL3,BCL2L2,SMOC1,ARHGEF7,SYT4,LUZP2,GNAS,CAMTA1,CDK5R2,WWC1,GPM6A,TCF7L2,MFSD2A,CDC42,TPM4,HMGB1,ZFYVE9,CCSER2,BTF3L4,PRRX1,NSD2,ACBD5,FEZ2,PRKACB,KIAA0513,GON4L,CADM2,CEP170,CSDE1,OCIAD1,SMG7,KCND3,RABGAP1L,WIPF2,RAB5B,ATG16L1,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100" MicroRNA "GTGCCTT,MIR-506:MSigDB" "GTGCCTT,MIR-506:MSigDB" MSigDB 2.38E-21 1.29E-17 1.14E-20 1.04E-19 48 672 "EPS8,EYA1,RYR1,SORCS1,SCN4B,SEMA6A,GPAM,SLITRK3,JAKMIP3,SFMBT2,SHANK2,SLIT1,MTR,PALLD,ZCCHC24,KIF21B,LMO3,DCAF5,PHLDB1,NHLH1,CAMTA1,MYRF,PTBP2,NUMA1,GRIA2,GRID1,RFFL,TMEM257,KCNK10,PCDH8,PCDH9,PDE4B,GDAP1L1,NEGR1,TJP2,PRRX1,CTNND1,EDRF1,SPIRE1,PRDM2,BLOC1S6,PTPRZ1,SRGAP3,KCNK2,DNM2,RALGDS,RFX4,RBM12" MicroRNA hsa-miR-1225-5p:mirSVR_lowEffct hsa-miR-1225-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-21 1.32E-17 1.16E-20 1.07E-19 58 989 "ATAT1,LDLRAD3,CSMD2,WLS,CHST15,SCNN1D,LRRC7,TRIM46,ITSN1,DGKD,BCAS1,API5,SLC8A2,MT3,CCDC88A,ASPH,NRG3,TNIK,CADM3,ADAM15,FXYD6,NFASC,BCL2L2,VAMP1,SYT4,CACNA1E,ZEB1,PCDHGA3,RFFL,GRIN1,GPR88,CRB1,TGFBR3,TMEM257,PADI2,TPD52,TPM4,PLEKHB1,ZFYVE9,CHD1L,USP54,PUM1,NTM,RABGAP1L,KCNN3,RAB5B,PID1,PARP11,FAM57B,DPP6,DTNA,L1CAM,NUP214,VANGL2,SYT15,SEC61A2,YY1AP1,EPB41L2" MicroRNA hsa-miR-550:mirSVR_highEffct hsa-miR-550:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-21 1.43E-17 1.26E-20 1.16E-19 45 587 "ADCY2,WAC,SORCS1,HOGA1,FGF1,TRIM46,MAGI3,SLITRK3,ARHGAP5,SLC8A3,RCOR3,ATM,ATP1A2,CAB39,GART,NCAM1,BCL2L2,ERBIN,RND1,GLS,ADGRL3,KLHL4,ACSL6,CACNA1E,CACNB2,GRIK3,TMEM25,IGSF21,TNR,C1orf94,LGI1,CASC2,TLX1,NLGN3,CADM1,TJP2,PLXNB3,SNCAIP,USP54,GON4L,SV2A,KCNJ9,CCDC3,FAM66C,NUP214" MicroRNA hsa-miR-4289:mirSVR_highEffct hsa-miR-4289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.70E-21 1.46E-17 1.29E-20 1.18E-19 52 796 "ABAT,SYT9,KCNIP2,CLIP1,KLHL32,ERMN,FGF14,SELL,ANXA7,PPM1E,NTNG1,ZNF365,RUFY2,ASCL1,SMARCE1,RCOR3,SON,HEPN1,FAM168A,VXN,GRIA2,GRIA4,GRIK2,OMG,MFSD2A,TMEM257,HPS5,TPM3,PDE4B,BEST3,TMEFF2,JAM2,CADM1,TENM4,ATRNL1,VCAN,MASP1,BRINP3,PTHLH,CADM2,CNIH3,CEP170,AK5,RABGAP1L,PCDH15,PARP11,FAM13C,DTNA,SLC6A15,ARHGAP12,CBLN2,RCAN2" MicroRNA hsa-miR-3144-3p:mirSVR_highEffct hsa-miR-3144-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-21 1.57E-17 1.38E-20 1.27E-19 56 926 "RABEPK,CNTNAP3,CEND1,EYA1,MDM4,CSMD3,KLHL32,SORCS1,SLC44A5,GPR158,KIAA1109,LRRC7,SLC30A10,SGIP1,PKP4,SH3GL2,NTNG1,NLGN1,SLC1A7,SCG3,ASTN1,EIF4G3,DNER,NAP1L2,DDHD2,ATF7,CACNA1E,TCF7L2,CECR2,GRID1,GPR88,TLL2,TMEM257,NRXN1,NEGR1,PMP2,PACSIN1,NSD2,MFSD4A,PRKACB,NRSN1,EDRF1,ZBTB16,PRTFDC1,COPS7A,MAGI2,OCIAD1,RABGAP1L,PCDH15,CAB39L,KLRC2,PARP11,DPP6,SH3GLB1,YY1AP1,RCAN2" MicroRNA hsa-miR-518a-5p:PITA hsa-miR-518a-5p:PITA_TOP PITA 2.93E-21 1.59E-17 1.39E-20 1.28E-19 42 506 "ASIC1,KCNIP2,AMER2,TOMM40L,ITSN1,SESN3,API5,MIER1,RCOR3,IGSF9B,PALLD,SOX5,ZCCHC24,NPAS3,RAP1GAP2,NCAM1,NEUROD1,RND1,TBX15,CACNA1E,TCF12,HAP1,CAMK2A,TNS1,RBFOX2,LGI1,ACBD5,POU3F2,CRMP1,RIMS4,PUM1,DNAJC6,KCNA1,PTPRD,SV2A,SRGAP3,KCNK2,SNX27,DSCAM,INSYN2,PIANP,EPB41L1" MicroRNA hsa-miR-527:PITA hsa-miR-527:PITA_TOP PITA 2.93E-21 1.59E-17 1.39E-20 1.28E-19 42 506 "ASIC1,KCNIP2,AMER2,TOMM40L,ITSN1,SESN3,API5,MIER1,RCOR3,IGSF9B,PALLD,SOX5,ZCCHC24,NPAS3,RAP1GAP2,NCAM1,NEUROD1,RND1,TBX15,CACNA1E,TCF12,HAP1,CAMK2A,TNS1,RBFOX2,LGI1,ACBD5,POU3F2,CRMP1,RIMS4,PUM1,DNAJC6,KCNA1,PTPRD,SV2A,SRGAP3,KCNK2,SNX27,DSCAM,INSYN2,PIANP,EPB41L1" MicroRNA hsa-miR-140-3p.1:TargetScan hsa-miR-140-3p.1 TargetScan 3.03E-21 1.64E-17 1.44E-20 1.32E-19 41 480 "ADD3,SCN3A,MOBP,ITSN1,ARHGAP5,CAPRIN2,MYT1L,KIF1B,CACNA1E,HAP1,CAMK2G,GRIA1,GRIA4,GRIK2,KCNK10,CDH8,SCRG1,HNRNPK,DLGAP3,KIAA1549L,CAMKV,PACSIN1,ACBD5,NCAN,PRKAB2,MAPK8,ANKS1B,PTCH1,CADM2,ELMO1,HP1BP3,CEP170,KCNJ9,ARNT2,KIF2A,RAB5B,RTN4,RFX5,RBM12,ARHGAP12,ELAVL3" MicroRNA hsa-miR-597:mirSVR_highEffct hsa-miR-597:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.03E-21 1.64E-17 1.44E-20 1.32E-19 41 480 "GPR158,LINC00461,PLA2G6,LRRC7,FGF14,ASRGL1,ANK2,SLITRK3,LRRC4C,DNAH17,SMARCE1,RCOR3,NAP1L2,NCAM1,RGL1,GANAB,GLS,CNDP1,GPM6A,CACNA1E,CACNB2,PTBP2,VXN,GRIA4,GRIK2,MAEL,PDE1C,FNDC5,TLX1,NEGR1,BEST1,ARHGEF4,FGFR1OP2,MASP1,WBP1L,KCNA2,KCNK2,PEX5,FAM135B,SH3GLB1,VWA5A" MicroRNA hsa-miR-142-3p.2:TargetScan hsa-miR-142-3p.2 TargetScan 3.12E-21 1.69E-17 1.48E-20 1.36E-19 39 429 "CDC7,ANK2,ANK3,APC,RUFY2,ARHGAP5,CCDC88A,ASPH,ATP2B2,RAP1GAP2,NFASC,PHLDB1,NFIA,CAMSAP2,CACNA1E,GRIA1,GPR88,MFSD2A,DCLK1,RBFOX2,MAGI1,HNRNPK,NLGN3,NEGR1,ANLN,OSBPL3,RBPJ,DOCK7,PKN2,CTNND1,PUM1,PROX1,ANKS1B,JAKMIP2,CADM2,CEP170,RABGAP1L,ATG16L1,ABI2" MicroRNA hsa-miR-636:mirSVR_highEffct hsa-miR-636:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-21 1.70E-17 1.48E-20 1.36E-19 46 618 "RTN3,ADARB2,AMER2,AGT,SEMA6A,ANK1,SHTN1,LRRC55,DACH2,CGREF1,SORCS3,SOX5,TTLL9,KIRREL3,TBX15,VSTM2A,GRIK2,AIFM1,HPS5,TNS1,PCDH9,LGI1,TPD52,PRMT8,FNDC5,JAM2,DUSP26,GDAP1L1,IFFO1,RBPJ,PRKACB,PKN2,PUM1,MASP1,BRINP3,SYNC,LRRTM3,CA10,PRTFDC1,HP1BP3,OCIAD1,KCNH1,RABGAP1L,KCNMA1,RFX4,ATL1" MicroRNA hsa-miR-6835-3p:TargetScan hsa-miR-6835-3p TargetScan 3.24E-21 1.76E-17 1.53E-20 1.41E-19 48 677 "RIMKLA,RTN3,CSMD3,ADCYAP1R1,GRAMD1B,SCN4B,FHL1,CDC42BPA,PPM1E,APC,NTNG1,GPAM,BRINP2,FYN,NPAS3,NFIA,GPM6B,CAMK2A,PSD3,RFFL,OPCML,KCNK10,RBFOX2,PDE1C,NRXN1,ANLN,CNTN1,PRRX1,FAT3,ACBD5,MED1,PPP2R5C,PRKAB2,CTNND2,BRINP3,DPYSL5,JAKMIP2,KCNA4,PTPRD,KCNN3,NKAIN1,FAM57B,PHC2,EFNA3,ABI2,CBLN2,EPB41L1,RCAN2" MicroRNA hsa-miR-495-3p:TargetScan hsa-miR-495-3p TargetScan 3.34E-21 1.81E-17 1.58E-20 1.45E-19 46 619 "DPF1,LDLRAD3,GPR158,FOXG1,APC,NTNG1,CCDC88A,NSG2,PDE8B,B3GAT1,ATP2B2,GAD2,NPAS3,RAP1GAP2,AJAP1,RHBDL3,DDHD2,CNTN2,ACSL6,CAMK2G,RFFL,PCDH8,RBFOX2,GPR37L1,HMGB1,LRTM2,CADM1,KIAA1549L,NRXN2,NEGR1,NMT2,FTO,BTF3L4,POU3F2,CRLS1,RIMS4,CTNND2,MAPK10,LRRTM3,HP1BP3,KCNN3,RFX4,RBM12,RPRD1A,RAVER2,ELAVL3" MicroRNA hsa-miR-491-3p:mirSVR_highEffct hsa-miR-491-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.42E-21 1.85E-17 1.61E-20 1.48E-19 64 1205 "EPS8,CLIP1,RTN1,ADD3,FABP7,KIAA1109,LRRC7,SEMA6A,SLC30A10,MOBP,SOX6,ANK3,APBA2,SLITRK3,SYBU,RUFY2,LRRC55,ARHGAP5,SCG3,ASPH,SORCS3,SMARCE1,MYT1L,B3GALT2,EMC1,KIF1B,NAP1L2,C11orf87,ERBIN,RGL1,ARHGEF7,PCDH11X,LUZP2,GPM6B,GRIA1,GRIA4,GRIK3,OLR1,TGFBR3,TMEM257,PCDH9,RBFOX2,TPM3,POU3F2,CHD1L,FMN2,PKN2,FGFR1OP2,LRRTM3,PTHLH,MAGI2,KCNA2,PLPPR4,DLG2,KLRC2,TMEM255A,SLC17A6,ABI1,GOPC,ABCC9,SLC6A15,ZYG11B,RBM12,RPE65" MicroRNA hsa-miR-658:mirSVR_lowEffct hsa-miR-658:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.42E-21 1.85E-17 1.61E-20 1.48E-19 59 1030 "RABEPK,ACHE,MEG3,CSMD2,PNMA8B,CHST15,FHL1,SEMA6C,ANK3,PKP4,ST3GAL3,SFMBT2,SLC8A3,ASPH,SORCS3,RCOR3,TNIK,ZSWIM8,NFASC,C11orf87,GPR162,SEMA4A,CDK5R2,TCF7L2,NRGN,GRID1,PAH,CD81,HRH3,ARHGAP19,TPM3,MAGI1,PRMT8,GPR37L1,UBTF,FTO,CABP1,MFSD4A,FEZ1,MICAL2,PRKCG,PKN2,CTNND1,EDRF1,RIMS3,PTHLH,PRDM2,MAGI2,SMG7,NTM,PID1,ATN1,BSDC1,CAMK1G,NUP214,ARHGEF10L,EEF1A2,SFXN5,EN2" MicroRNA hsa-miR-144:PITA hsa-miR-144:PITA_TOP PITA 3.71E-21 2.01E-17 1.75E-20 1.60E-19 45 592 "LGR4,ARID1A,GPR158,SEMA6A,FOXG1,CACHD1,CLSTN1,ARHGAP5,CCDC88A,CADPS,ASCL1,SORCS3,ATP2B2,SOX1,MYT1L,RGL1,LUZP2,CAMSAP2,CACNB2,TJP1,TMEM257,PDE3B,KIAA1549L,PRRX1,ACBD5,PRKACB,FMN2,USP54,PUM1,TOX,SYTL2,CADM2,RGMA,CEP170,KCNA4,SRGAP3,ABI1,PAK5,INSYN2,RBM12,SH3GLB1,ABI2,SLC4A10,EPB41,EPB41L1" MicroRNA hsa-miR-331-5p:mirSVR_highEffct hsa-miR-331-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.83E-21 2.07E-17 1.80E-20 1.65E-19 53 834 "RABEPK,EPS8,LGR4,IL17D,KLHL32,ADCY2,WAC,GRAMD1B,FOXG1,ASRGL1,USP28,PPFIA1,ANXA7,GPAM,USP16,AQP4,RUFY2,LRRC55,ARHGAP5,PHYHIPL,MYT1L,SPART,NDUFA5,SYT4,UNC5D,CACNB2,TCF12,PTBP2,EML4,CECR2,CRB1,INA,ARHGAP19,PCSK2,CIART,PFKFB3,CASC2,A2ML1,PRRX1,CNRIP1,MFSD4A,FEZ2,PLD5,KIAA0408,KIAA0513,SYNC,LRRTM3,JAKMIP2,BDNF-AS,RABGAP1L,DPP6,ABCC9,RET" MicroRNA hsa-miR-3144-3p:mirSVR_lowEffct hsa-miR-3144-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.00E-21 2.17E-17 1.89E-20 1.73E-19 63 1173 "ACER3,SYT9,CSMD2,CDC7,LINC00461,BCAR3,HPCAL4,FOXG1,SFPQ,ANK3,FOLH1,USP28,PPM1E,ARHGAP5,SLC8A3,SLCO1A2,SLIT1,C10orf105,TMEM151A,ATP2B2,DKK3,FXYD6,NCAM1,C11orf87,CLASP2,GLS,PCDH11X,SYT4,TCF12,HAP1,NUDT21,GRIA1,GRIA4,MAEL,REPS2,MAGI1,PDE1C,ANO5,TMEFF2,KIAA1549L,PRRX1,MED1,CRLS1,SNCAIP,TENM4,RBPJ,DOCK7,CTNND1,ANKS1B,TOMM20,ITGAV,CADM2,ZC3H11A,C1orf109,DLG2,DTNA,SLC6A15,JMJD1C,INSYN2,ABI2,ELAVL4,RPE65,BAALC" MicroRNA hsa-miR-9:PITA hsa-miR-9:PITA_TOP PITA 4.24E-21 2.29E-17 1.99E-20 1.83E-19 45 594 "ASIC1,SYT9,ARID1A,TESK2,LRRTM4,FOXG1,NTNG1,GPAM,ST3GAL3,SHTN1,CCDC88A,SMARCE1,WDTC1,SPART,NFASC,ERBIN,GLS,VAMP1,UNC5D,CACNA1E,CACNB2,PTBP2,PSD3,GPR88,OPCML,RBFOX2,PCSK2,MAGI1,ACOT7,CCSER2,PRRX1,PACSIN1,POU3F2,PTPA,MICAL2,TOMM20,JAKMIP2,KCNA1,SRGAP3,WIPF2,ABI1,GOPC,FAM13C,RPE65,SEZ6" MicroRNA hsa-miR-208a:mirSVR_lowEffct hsa-miR-208a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.26E-21 2.31E-17 2.00E-20 1.84E-19 53 836 "MEG3,F3,KLHL32,TESK2,SH3GL2,APC,MAGI3,SYBU,PAAF1,ZNF365,ASCL1,SPHKAP,SMARCE1,ATP1A2,SON,SOX5,B4GALNT1,KIF1B,ADGRB2,NDUFA5,RGL1,PCDH11X,KAZN,PRUNE2,TCF12,PTBP2,VSTM2A,OMG,RBFOX2,PDE1A,PDE2A,HMGB1,CASC2,DNAJC12,NXPH1,ACBD5,RNF14,PPP3CB,RGS6,MAPK8,MAPK10,BRINP3,ANKS1B,CA10,CADM2,HP1BP3,PTPRO,PCDH15,KCNN3,SLC17A6,ABI1,SLC39A12,TMEM100" MicroRNA hsa-miR-503:mirSVR_lowEffct hsa-miR-503:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-21 2.35E-17 2.04E-20 1.87E-19 56 934 "SYNDIG1,FAM43B,CSMD3,GALNT13,LRRC7,PPFIA1,ITSN1,APC,NTNG1,ZNF365,SLC2A5,CCDC181,SON,ARPP21,SALL3,TTLL9,DNER,NCAM1,ADHFE1,NEUROD1,FAM168A,VAMP1,SYT4,CAMTA1,LRIT2,GPR88,OMG,CRB1,LEFTY2,USP2,MAGI1,ANLN,PLXNB3,BTF3L4,NSD2,NXPH1,PPP3CB,KLK6,WBP1L,PTHLH,PTPRD,RABGAP1L,TMCC2,KCNK2,KIF2A,TMEM255A,DNM2,RAD52,RALGDS,RTN4,L1CAM,ZYG11B,RET,RFX4,ARHGEF10L,SLC4A10" MicroRNA hsa-miR-4318:mirSVR_highEffct hsa-miR-4318:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.40E-21 2.38E-17 2.06E-20 1.89E-19 48 682 "ACER3,TMEM74,ATAT1,ARID1A,NLGN4X,SCN3A,TRIM46,PPFIA1,ITSN1,MAGI3,CACHD1,API5,SHTN1,NBPF1,RUFY2,B3GAT1,SNAP25,KIF1B,NCAM1,SMOC1,ZNF638,CAMSAP2,ANO4,VWC2,ZEB1,CYB561A3,TGFBR3,P2RX7,AIFM1,MAEL,PCDH8,PCDH9,TPM3,BEST3,NRXN1,MED1,CRMP1,RBPJ,ANKS1B,PLPPR1,CADM2,CEP170,KCNA2,DTNA,PAK5,RFX4,EPB41,UEVLD" MicroRNA hsa-miR-124:mirSVR_highEffct hsa-miR-124:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.48E-21 2.42E-17 2.10E-20 1.93E-19 61 1105 "EPS8,RYR1,ERMN,SLC44A5,SEMA6A,ANXA7,NTNG1,SLITRK3,BCO1,MSRA,SMARCE1,ATP2B2,PALLD,TNIK,ZCCHC24,GAD2,NEK6,NEUROD1,MYRF,ANO4,PTBP2,CECR2,NUMA1,GRIA2,GRIA4,GRID1,LINC00839,USP2,TMEM257,KCNK10,CD81,PCDH8,PCDH9,PCSK2,PDE4B,TUB,GDAP1L1,NRXN1,TJP2,CNTN1,PRRX1,ETNPPL,SF1,SNCAIP,PPP3CB,VCAN,PKN2,CTNND1,EDRF1,CSDE1,OCIAD1,PTPRD,C1orf109,PTPRZ1,KCNK2,KIF2A,ZYG11B,RFX4,JMJD1C,VWA5A,ARHGAP12" MicroRNA hsa-miR-6867-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.50E-21 2.43E-17 2.11E-20 1.93E-19 40 459 "NLGN4X,FGF14,FOXG1,SLITRK3,BCAS1,RPH3A,SON,SOX5,NMNAT2,KIF1B,GFRA1,NCDN,PCDH11X,ASTN2,FAM69C,ZEB1,TMEM151B,OLR1,KCNK10,TNR,LRTM2,TUB,NLGN3,KIAA1549L,NRXN1,CCSER2,SPATA6,NCAN,DOCK7,MAPK10,PROX1,DPYSL5,DNAJC6,JAKMIP2,KCNN3,GNE,TTLL7,SSPN,ABI2,EN2" MicroRNA hsa-miR-663b:mirSVR_lowEffct hsa-miR-663b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-21 2.59E-17 2.24E-20 2.06E-19 64 1213 "MAP6,ASIC1,IL17D,SLC25A25,NDRG2,PNMA8B,ADORA1,SCN4B,GOLGA7B,PKP4,APBA2,MAGI3,CCDC80,DGKD,LRRC55,CCDC88A,SHANK2,ARFGAP1,KBTBD12,B3GAT1,PHYHIPL,ATP2B2,TNIK,ADAM15,NCAM1,NEUROD1,ARHGEF7,RHBDL3,NHLH1,KAZN,GNAS,CACNA1A,NEU4,TCF7L2,HAP1,AZIN2,TMEM151B,RFFL,MAGI1,PDE1A,PDE4B,ASIC3,OPALIN,FADS2,ST8SIA5,C11orf49,MFSD4A,MICAL2,PRKAB2,PRKCZ,SPIRE1,PLPPR1,SRGAP3,KCNK2,KCNMA1,FAM66C,ATN1,RASGRF1,USH1C,ZNF248,SEC61A2,PIANP,OLIG2,EPB41L1" MicroRNA hsa-miR-125b-5p:TargetScan hsa-miR-125b-5p TargetScan 4.86E-21 2.63E-17 2.27E-20 2.09E-19 47 654 "ABAT,RIMKLA,ASIC1,ACHE,EMID1,FAM43B,AMER2,SCN4B,FGF14,PKP4,APC,CGREF1,GPR153,C10orf105,NRG3,BCL2L2,ACSL6,DIRAS1,CECR2,BRSK2,RFFL,AIFM1,KCNK10,DAAM2,RBFOX2,NRXN1,OPALIN,IFFO1,PPP2R5C,NCAN,PHACTR3,MAPK10,FAM131B,PROX1,PHYHIP,KCNA1,C1orf109,KCNH1,KCNJ9,PARP11,GOPC,RASGRF1,RFX5,FAM135B,PHC2,ABI2,ELAVL4" MicroRNA hsa-miR-125a-5p:TargetScan hsa-miR-125a-5p TargetScan 4.86E-21 2.63E-17 2.27E-20 2.09E-19 47 654 "ABAT,RIMKLA,ASIC1,ACHE,EMID1,FAM43B,AMER2,SCN4B,FGF14,PKP4,APC,CGREF1,GPR153,C10orf105,NRG3,BCL2L2,ACSL6,DIRAS1,CECR2,BRSK2,RFFL,AIFM1,KCNK10,DAAM2,RBFOX2,NRXN1,OPALIN,IFFO1,PPP2R5C,NCAN,PHACTR3,MAPK10,FAM131B,PROX1,PHYHIP,KCNA1,C1orf109,KCNH1,KCNJ9,PARP11,GOPC,RASGRF1,RFX5,FAM135B,PHC2,ABI2,ELAVL4" MicroRNA hsa-miR-199b-3p:mirSVR_lowEffct hsa-miR-199b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-21 2.65E-17 2.28E-20 2.09E-19 68 1360 "ZFYVE27,MAPT,WAC,FABP7,SORCS1,FCGR1A,FHL1,FOXM1,TRIM46,ITSN1,PKP4,SORBS1,NLGN1,LRRC4C,API5,PAAF1,SLIT1,SORCS3,TNIK,ILDR2,ALDH1L1,STOX1,RGL1,ADHFE1,NEUROD1,SLCO1C1,GLS,SYT4,GNAS,ADGRL3,PRUNE2,ZEB1,CAMK2G,VXN,GRIA1,ATP13A2,TJP1,REPS2,CDC42,LGI1,PDE3B,PRMT8,TMPRSS5,TMEFF2,JAM2,HEPACAM,SEMA5B,CCSER2,DNAJC12,BEST1,ACBD5,MED1,PPP3CB,PHACTR3,PRKACB,RAB39A,TOX,PRDM2,HP1BP3,PTPRO,KCNK1,PCDH15,FAM66C,ABI1,PAK5,RFX4,JMJD1C,EPB41L1" MicroRNA hsa-miR-199a-3p:mirSVR_lowEffct hsa-miR-199a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-21 2.65E-17 2.28E-20 2.09E-19 68 1360 "ZFYVE27,MAPT,WAC,FABP7,SORCS1,FCGR1A,FHL1,FOXM1,TRIM46,ITSN1,PKP4,SORBS1,NLGN1,LRRC4C,API5,PAAF1,SLIT1,SORCS3,TNIK,ILDR2,ALDH1L1,STOX1,RGL1,ADHFE1,NEUROD1,SLCO1C1,GLS,SYT4,GNAS,ADGRL3,PRUNE2,ZEB1,CAMK2G,VXN,GRIA1,ATP13A2,TJP1,REPS2,CDC42,LGI1,PDE3B,PRMT8,TMPRSS5,TMEFF2,JAM2,HEPACAM,SEMA5B,CCSER2,DNAJC12,BEST1,ACBD5,MED1,PPP3CB,PHACTR3,PRKACB,RAB39A,TOX,PRDM2,HP1BP3,PTPRO,KCNK1,PCDH15,FAM66C,ABI1,PAK5,RFX4,JMJD1C,EPB41L1" MicroRNA hsa-miR-1293:mirSVR_lowEffct hsa-miR-1293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.20E-21 2.82E-17 2.42E-20 2.22E-19 69 1399 "PRR5L,CNTNAP3,CEND1,MRVI1,CSMD2,ADARB2,KLHL32,AMER2,ASIC4,SEMA6C,APBA2,JAKMIP3,LRRC55,ARFGAP2,MT3,SHANK2,SORCS3,SOX10,B4GALNT1,ARPP21,NFASC,NCAM1,CLASP2,GPR162,ADHFE1,PHLDB1,GANAB,DCLK2,CAMSAP2,DDR1,AZIN2,HPS5,CDH8,TPM3,TPM4,ZMYND8,BEST3,LRTM2,KIAA1549L,UBTF,A2ML1,ST8SIA5,CCDC136,RGS6,PRKCG,CTNND1,NRSN1,FGFR1OP2,BRINP3,KLK6,PSD,RIMS3,GON4L,ZNF385B,PRDM2,SRGAP3,KCNJ4,TMCC2,KCNK1,NAV2,SNX27,NKAIN1,WIPF2,DNM2,L1CAM,CAMK1G,SYT15,RAVER2,ELAVL3" MicroRNA hsa-miR-601:mirSVR_lowEffct hsa-miR-601:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-21 2.87E-17 2.46E-20 2.26E-19 55 905 "ACER3,ATAT1,CSMD2,CSMD3,ADCY2,GRAMD1B,GPR158,FGR,GOLGA7B,FOXG1,NTNG1,MIER1,LRRC55,ARHGAP5,MT3,CADPS,CAPRIN2,CCDC181,B4GALNT1,TTLL9,NFASC,COLGALT2,GLS,PCDH11X,ZNF638,C1QC,KLHL4,ANO4,CAMK2A,TNFRSF1B,PCDH9,PCSK2,PDE2A,BEST3,PFKFB3,ASIC3,KIAA1549L,ST8SIA5,CRLS1,PPP3CB,KLK6,SIRPA,DNAJC6,CNIH3,LRP8,CEP170,AK5,KCNJ10,DBX2,ZYG11B,RFX5,FAM135B,SEC61A2,RNF220,EPB41" MicroRNA hsa-miR-17-5p:Functional MTI Functional MTI miRTarbase 5.64E-21 3.06E-17 2.63E-20 2.41E-19 63 1181 "RTN3,SYNDIG1,ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,GPAM,USP16,RUFY2,ARHGAP5,CAPRIN2,EIF4G3,GABBR1,SON,EMC1,SALL3,NPAS3,BCL2L2,SMOC1,GANAB,ARHGEF7,LUZP2,GNAS,CAMTA1,WWC1,GPM6A,TCF7L2,PSD3,MFSD2A,TMEM9,TJP1,TPM4,HMGB1,ZFYVE9,CCSER2,BTF3L4,NSD2,ACBD5,FEZ2,PRKACB,KIAA0513,SIRPA,CADM2,CEP170,CSDE1,OCIAD1,PTPRO,KCND3,RABGAP1L,KCNMA1,WIPF2,RAB5B,ATG16L1,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100,EPB41L2" MicroRNA hsa-miR-4255:mirSVR_highEffct hsa-miR-4255:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.86E-21 3.17E-17 2.72E-20 2.50E-19 53 842 "ACER3,DSCAML1,CDC7,AMER2,SLC44A5,FCGR1A,SEMA6A,MOG,FOXM1,AMPH,APC,NTNG1,AQP4,RUFY2,ARHGAP5,CCDC88A,CAPRIN2,ASPH,MTR,SMARCE1,IDI2-AS1,ADHFE1,ARHGEF7,NKX2-2,CAMTA1,CECR2,GRIA1,GPR88,TMEM25,MFSD2A,HPS5,TPM3,PDE4B,LINC01102,BEST3,CASC2,A2ML1,TJP2,NSD2,NXPH1,CP,CHD1L,MICAL2,RBPJ,DOCK7,PLPPR5,CEP170,CSDE1,PCDH15,ABCC9,SSPN,SLC4A10,EPB41L2" MicroRNA hsa-miR-323-5p:mirSVR_lowEffct hsa-miR-323-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.04E-21 3.27E-17 2.81E-20 2.57E-19 62 1147 "CNTNAP3,RCSD1,MEG3,ECSIT,WLS,RTKN,MDM4,KLHL32,SORCS1,ANK3,ITSN1,PKP4,ST3GAL3,ZNF365,LRRC55,PKNOX2,ARFGAP2,GPR153,SMARCE1,WDTC1,B3GALT2,NCAM1,GANAB,AJAP1,RHBDL3,C1QC,OS9,CAMSAP2,UNC5D,CNTN2,PRUNE2,WSCD1,CACNA1E,DDR1,AZIN2,VXN,VSTM2A,GRID1,ATP13A2,TJP1,CDC42,TNS1,SEZ6L,GDAP1L1,UBTF,CNTN1,BEST1,CHD1L,RGS6,VCAN,FGFR1OP2,PSD,OLFM3,KCNC1,KCNMA1,KLRC2,RAD52,ABCC9,RET,ARHGEF10L,GPR61,ABI2" MicroRNA hsa-miR-144*:mirSVR_lowEffct hsa-miR-144*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.57E-21 3.56E-17 3.05E-20 2.80E-19 71 1481 "RABEPK,SDE2,ACER3,CDHR1,TMEM74,WLS,CSMD3,GALNT13,SORCS1,ADORA3,SCN3A,LRRTM4,KIAA1109,BCAR3,SH3GL2,CCDC80,GPAM,CACHD1,SHTN1,SLC14A1,SLCO1A2,SPHKAP,ASPH,SORCS3,DKK3,USP33,CAB39,KIF1B,DNER,NCDN,NEUROD1,GLS,ZNF638,C1QC,ACSL6,CACNB2,BRSK2,GRIA4,GRIN1,LINC00839,TMEM25,KCNK10,DCLK1,PDE3B,ADGRG1,HMGB1,ZBED5,NLGN3,KIAA1549L,FTO,FAT3,CNRIP1,PRKAB2,CTNND2,GON4L,BLOC1S6,KCNA2,PLPPR4,PTPRZ1,SRGAP3,NTM,KCNJ10,KCNK2,PCDH15,FAM13C,JMJD1C,TTLL7,SEC61A2,ABI2,RAVER2,SLC4A10" MicroRNA hsa-miR-18a:mirSVR_highEffct hsa-miR-18a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.62E-21 3.58E-17 3.07E-20 2.81E-19 49 719 "SLC25A25,ADD3,AMER2,GPR158,LINC00461,FGF1,BCAR3,BBOX1,ANK3,ITSN1,ANXA7,MAGI3,ZNF365,ATM,SON,CAB39,IDI2-AS1,SPART,C11orf87,GNAS,ANO4,GPR88,TLL2,DAAM2,CDC42,PDE1A,CASC2,NRXN1,SLC25A27,COL9A2,PRRX1,RNF14,PPP3CB,RGS6,ATRNL1,PRKACB,DZIP3,NRSN1,MASP1,TOMM20,SYNC,CADM2,HP1BP3,TMCC2,INSYN2,ARHGEF10L,SYT15,CBLN2,EPB41L1" MicroRNA hsa-miR-374b-5p:TargetScan hsa-miR-374b-5p TargetScan 6.86E-21 3.72E-17 3.18E-20 2.91E-19 43 545 "ABAT,CSMD2,GRAMD1B,FOXG1,ANK3,APC,GAS7,ARHGAP5,ASCL1,PDE8B,ATP2B2,MYT1L,C11orf87,NEUROD1,NFIA,NKX2-2,CAMSAP2,ACSL6,PAX6,DCLK1,RBFOX2,JAM2,ANLN,RNF14,PLD5,KIAA0408,BRINP3,DNAJC6,PMEPA1,CADM2,BLOC1S6,KCNN3,DLG3,RAB5B,RALGDS,GOPC,FAM13C,L1CAM,BSDC1,RFX4,ELAVL4,EN2,EPB41L1" MicroRNA hsa-miR-374a-5p:TargetScan hsa-miR-374a-5p TargetScan 6.86E-21 3.72E-17 3.18E-20 2.91E-19 43 545 "ABAT,CSMD2,GRAMD1B,FOXG1,ANK3,APC,GAS7,ARHGAP5,ASCL1,PDE8B,ATP2B2,MYT1L,C11orf87,NEUROD1,NFIA,NKX2-2,CAMSAP2,ACSL6,PAX6,DCLK1,RBFOX2,JAM2,ANLN,RNF14,PLD5,KIAA0408,BRINP3,DNAJC6,PMEPA1,CADM2,BLOC1S6,KCNN3,DLG3,RAB5B,RALGDS,GOPC,FAM13C,L1CAM,BSDC1,RFX4,ELAVL4,EN2,EPB41L1" MicroRNA hsa-miR-140-3p:mirSVR_highEffct hsa-miR-140-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.08E-21 3.84E-17 3.28E-20 3.01E-19 54 878 "PRR5L,LGR4,CLIP1,DSCAML1,SLC44A5,GPR158,LRRC7,MOBP,FOXG1,ERICH3,SGIP1,AQP4,ASPH,SNAP25,NRG3,SON,ARPP21,KIF1B,DNER,NAP1L2,VAMP1,PCDH11X,ZNF638,DCLK2,GOLGB1,ZEB1,INA,TLL2,PCDH8,RBFOX2,LILRA4,MAGI1,HMGB1,SCRG1,JAM2,NOMO2,P2RY12,PPP3CB,CHD5,NCAN,PLPP4,GON4L,SYNC,SIRPA,HP1BP3,SRGAP3,KCNK1,ABI1,GOPC,FAM13C,ZNF248,VANGL2,CBLN2,YY1AP1" MicroRNA hsa-miR-876-3p:mirSVR_highEffct hsa-miR-876-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.13E-21 3.86E-17 3.29E-20 3.02E-19 50 751 "TMEM74,ARID1A,MDM4,CDC7,SORCS1,SCN3A,LRRTM4,ANK3,ITSN1,MAGI3,PAAF1,ZNF365,ARHGAP5,ARFGAP2,SLC14A1,SCG3,BRINP2,SORCS3,SNAP25,PALLD,NFASC,FAM168A,GNAS,GPM6B,CAMK2G,OLR1,INA,GDAP1L1,UBTF,PACSIN1,PNKD,PRKACB,PRKCZ,FGFR1OP2,MASP1,WBP1L,PHYHIP,PTAFR,DNAJC6,ITIH2,ZC3H11A,OLFM3,PTPRD,KCNJ10,PCDH15,DLG2,WIPF2,SLC25A18,BSDC1,RFX4" MicroRNA hsa-miR-494:PITA hsa-miR-494:PITA_TOP PITA 7.39E-21 4.00E-17 3.41E-20 3.13E-19 44 574 "LGR4,CSMD3,DSCAML1,GPR158,ACTL6B,FHL1,ELMOD1,RASA3,TACC2,API5,SHTN1,ARHGAP5,SLC8A2,SMARCE1,PHYHIPL,B3GALT2,NMNAT2,NELL1,NEUROD1,ARHGEF7,CAMTA1,GRIK2,TMEM257,PDE4B,CADM1,KIAA1549L,NXPH1,POU3F2,DZIP3,IGSF1,CTNND2,JAKMIP2,ZC3H11A,KCNA1,DLG2,WIPF2,RAB5B,TMEM255A,ABI1,RGS7,INSYN2,LMO1,EN2,RCAN2" MicroRNA hsa-miR-1255a:mirSVR_highEffct hsa-miR-1255a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.04E-21 4.35E-17 3.71E-20 3.40E-19 48 692 "RTN3,WLS,KLHL32,SCN3A,PLA2G6,MOG,SGIP1,ITSN1,GPAM,ZCCHC17,NLGN1,PAAF1,PDE8B,SCG3,ASPH,NMNAT2,ADAM15,CASTOR3,CAMTA1,NODAL,CAMK2G,VXN,GRIA4,GRIK4,MFSD2A,INA,ZDHHC22,FNDC5,CHGA,PLEKHB1,DNAJC12,CNTN1,MICAL2,OSBPL3,DZIP3,IGSF1,CTNND2,LRRTM3,BDNF-AS,COPS7A,AK5,NAV2,HS3ST4,SLC17A6,SLC25A18,SLC6A15,RGR,SSPN" MicroRNA hsa-miR-620:mirSVR_highEffct hsa-miR-620:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-21 4.53E-17 3.86E-20 3.54E-19 57 981 "MEG3,CSMD3,ADARB2,ADCY2,FCGR1A,LRRTM4,BBOX1,FOXM1,ERICH3,NTNG1,GPAM,MIER1,MSR1,SPHKAP,KBTBD12,GABBR1,SON,B3GALT2,DNER,LMO3,PCDH11X,ZNF638,UNC5D,MMD2,TMEM136,CNDP1,TBX15,TCF12,TJP1,LGI1,MAGI1,ANO5,CASC2,PMP2,CELF5,NECAB2,NXPH1,VCAN,PRKACB,NRSN1,LRRTM3,BDNF-AS,ELMO1,KCNA4,PTPRD,PTPRO,C1orf109,AK5,HS3ST4,GOPC,DBX2,DTNA,ABCC9,SLC6A15,ZYG11B,RFX4,RGS7" MicroRNA hsa-miR-548s:mirSVR_highEffct hsa-miR-548s:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-21 4.67E-17 3.97E-20 3.65E-19 56 948 "RTN3,CLIP1,KIAA1109,FGF1,FOXG1,SH3GL2,NTNG1,MAGI3,CCDC80,NLGN1,ASPH,SORCS3,RCOR3,PHYHIPL,PALLD,SCN3B,SOX5,ERBIN,ARHGEF7,SYT4,GPM6A,ZEB1,PTBP2,NUDT21,VXN,NUMA1,AIFM1,PAX6,C1orf94,PDE1A,ACOT7,CASC2,MS4A7,OPALIN,DNAJC12,PMP2,CHD1L,MED1,MICAL2,VCAN,RBPJ,IGSF1,CTNND1,NRSN1,BDNF-AS,CSDE1,C1orf109,KCNN3,DLG2,PLEKHB2,ATG16L1,DBX2,ABCC9,JMJD1C,ABI2,ARHGAP12" MicroRNA hsa-miR-1323:PITA hsa-miR-1323:PITA_TOP PITA 9.59E-21 5.20E-17 4.41E-20 4.05E-19 47 665 "RIMKLA,CLIP1,RTN1,ADCY2,NLGN4X,GPR158,SCN4B,LRRC7,SEMA6A,AMPH,CDC42BPA,ANK1,ANK3,SESN3,GPAM,SHTN1,DACH2,ASCL1,MYT1L,SOX5,LHFPL4,CLASP2,NFIA,CAMTA1,GPM6A,NUDT21,OLR1,TLL2,PCSK2,PRMT8,UBTF,NSD2,MED1,CRMP1,KIAA0408,BRINP3,TOMM20,LRRTM3,PMEPA1,HP1BP3,ZC3H11A,OLFM3,PTPRD,DLG2,PAK5,ABI2,ELAVL3" MicroRNA hsa-miR-548o:PITA hsa-miR-548o:PITA_TOP PITA 9.59E-21 5.20E-17 4.41E-20 4.05E-19 47 665 "RIMKLA,CLIP1,RTN1,ADCY2,NLGN4X,GPR158,SCN4B,LRRC7,SEMA6A,AMPH,CDC42BPA,ANK1,ANK3,SESN3,GPAM,SHTN1,DACH2,ASCL1,MYT1L,SOX5,LHFPL4,CLASP2,NFIA,CAMTA1,GPM6A,NUDT21,OLR1,TLL2,PCSK2,PRMT8,UBTF,NSD2,MED1,CRMP1,KIAA0408,BRINP3,TOMM20,LRRTM3,PMEPA1,HP1BP3,ZC3H11A,OLFM3,PTPRD,DLG2,PAK5,ABI2,ELAVL3" MicroRNA hsa-miR-449a:mirSVR_highEffct hsa-miR-449a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.62E-21 5.21E-17 4.42E-20 4.05E-19 54 884 "ACER3,LGR4,MDM4,GPR158,LINC00461,LRRC7,ELMOD1,HPCAL4,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,RUFY2,CADPS,SORCS3,PHYHIPL,PALLD,SON,B3GALT2,ARPP21,KIF1B,CLASP2,ARHGEF7,GNAS,CAMTA1,GOLGB1,ANO4,CACNB2,GRID1,INA,TNR,LGI1,TPD52,GDAP1L1,CADM1,ST8SIA5,SULT4A1,SLC25A27,IGSF1,CTNND2,NOS1AP,SYNC,LRRTM3,CADM2,MAGI2,KCNA2,PTPRD,TMEM255A,SLC6A15,JMJD1C,SYT15,VWA5A" MicroRNA hsa-miR-449b:mirSVR_highEffct hsa-miR-449b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.62E-21 5.21E-17 4.42E-20 4.05E-19 54 884 "ACER3,LGR4,MDM4,GPR158,LINC00461,LRRC7,ELMOD1,HPCAL4,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,RUFY2,CADPS,SORCS3,PHYHIPL,PALLD,SON,B3GALT2,ARPP21,KIF1B,CLASP2,ARHGEF7,GNAS,CAMTA1,GOLGB1,ANO4,CACNB2,GRID1,INA,TNR,LGI1,TPD52,GDAP1L1,CADM1,ST8SIA5,SULT4A1,SLC25A27,IGSF1,CTNND2,NOS1AP,SYNC,LRRTM3,CADM2,MAGI2,KCNA2,PTPRD,TMEM255A,SLC6A15,JMJD1C,SYT15,VWA5A" MicroRNA hsa-miR-761:mirSVR_highEffct hsa-miR-761:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.66E-21 5.23E-17 4.43E-20 4.06E-19 55 917 "ACER3,MAP6,ACLY,RCSD1,KLHL32,WAC,SORCS1,SCN3A,FGF1,LRRC7,FGF14,FHL1,ANK3,NTNG1,ST3GAL3,CLSTN1,ZNF365,MT3,ASTN1,ATM,MYT1L,ARPP21,NPAS3,GPR162,RGL1,PCDH11X,CDK5R2,DDR1,CACNB2,PTBP2,GRIK2,PTPN5,PAH,TPM3,NOMO2,FTO,MEAF6,MFSD4A,PHACTR3,CMTM5,PUM1,EDRF1,ANKS1B,SPIRE1,JAKMIP2,BDNF-AS,PTHLH,COPS7A,SRGAP3,KLRC2,PID1,TMEM255A,RAD52,ZNF248,SLC4A10" MicroRNA hsa-miR-150*:mirSVR_highEffct hsa-miR-150*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-20 5.68E-17 4.79E-20 4.39E-19 56 952 "GRAMD1B,TOMM40L,SCN3A,LRRTM4,SFPQ,SGIP1,JAKMIP3,CCDC88A,CADPS,ASPH,SON,ARPP21,NPAS3,NCAM1,GANAB,SEPT3,ARHGEF7,ZNF638,GNAS,KLHL4,ACSL6,GPR88,OLR1,GUCY1A2,MAEL,CDH8,LGI1,PRMT8,HNRNPK,CNTN1,CP,PPP2R5C,SNCAIP,KCNT2,FGFR1OP2,ANKS1B,ZNF385B,LRRTM3,PTHLH,CADM2,PLPPR4,PTPRO,NTM,DLG2,KLRC3,SLC17A6,ABI1,FAM13C,PAK5,RFX5,JMJD1C,INSYN2,ZNF248,SLC4A10,ELAVL4,C2orf80" MicroRNA hsa-miR-520d-3p:TargetScan hsa-miR-520d-3p TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-302e:TargetScan hsa-miR-302e TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-18b*:mirSVR_lowEffct hsa-miR-18b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "SDE2,EYA1,CSMD2,FCGR1A,TOMM40L,TESK2,PPFIA1,APC,ST3GAL3,YPEL4,ASPH,EIF4G3,SON,B4GALNT1,ADAM15,FXYD6,BCL2L2,GANAB,ZNF638,TMEM136,PRUNE2,CRB1,TGFBR3,CELF3,ZFP91,DAAM2,MAEL,PADI2,RBFOX2,BEST3,TJP2,BEST1,FEZ1,NCAN,RBPJ,SDC3,FMN2,PLD5,ECE2,PTHLH,BLOC1S6,PARD6A,CCDC3,KCNMA1,NAV2,SLC6A15,NUP214,ZNF248,EPB41" MicroRNA hsa-miR-302c-3p.1:TargetScan hsa-miR-302c-3p.1 TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-520c-3p:TargetScan hsa-miR-520c-3p TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-520b:TargetScan hsa-miR-520b TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-373-3p:TargetScan hsa-miR-373-3p TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-520a-3p:TargetScan hsa-miR-520a-3p TargetScan 1.05E-20 5.70E-17 4.79E-20 4.39E-19 49 727 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-302d-3p:TargetScan hsa-miR-302d-3p TargetScan 1.11E-20 6.03E-17 5.05E-20 4.63E-19 49 728 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-302a-3p:TargetScan hsa-miR-302a-3p TargetScan 1.11E-20 6.03E-17 5.05E-20 4.63E-19 49 728 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-520e:TargetScan hsa-miR-520e TargetScan 1.11E-20 6.03E-17 5.05E-20 4.63E-19 49 728 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-372-3p:TargetScan hsa-miR-372-3p TargetScan 1.11E-20 6.03E-17 5.05E-20 4.63E-19 49 728 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA hsa-miR-302b-3p:TargetScan hsa-miR-302b-3p TargetScan 1.11E-20 6.03E-17 5.05E-20 4.63E-19 49 728 "EPS8,RIMKLA,LGR4,RTN1,AMER2,APC,LRRC4C,CCDC88A,PHYHIPL,ATP2B2,PALLD,MYT1L,KIF1B,NPAS3,LMO3,DCAF5,RGL1,NEUROD1,FAM168A,ACSBG1,NFIA,ARHGEF7,MYRF,GPM6A,CECR2,PSD3,OPCML,LEFTY2,RBFOX2,PRRX1,IFFO1,ACBD5,PRKACB,PKN2,NOS1AP,PROX1,KIAA0513,DPYSL5,CADM2,HP1BP3,LRP8,RGMA,KCNA1,CDH20,PTPRD,HS3ST4,RALGDS,FAM13C,ABI2" MicroRNA "ACCAAAG,MIR-9:MSigDB" "ACCAAAG,MIR-9:MSigDB" MSigDB 1.14E-20 6.18E-17 5.17E-20 4.74E-19 40 471 "ASIC1,SYT9,ARID1A,CHST15,TESK2,LRRTM4,FOXG1,ANK2,NTNG1,GPAM,SHTN1,ZNF365,SON,WDTC1,ARPP21,SPART,NFASC,ERBIN,VAMP1,MYRF,PTBP2,OPCML,RBFOX2,PCSK2,ACOT7,CCSER2,PRRX1,PACSIN1,NSD2,POU3F2,OSBPL3,RIMS4,RIMS3,SRGAP3,KCNMA1,RALGDS,GOPC,FAM13C,RET,SEZ6" MicroRNA hsa-miR-3147:mirSVR_lowEffct hsa-miR-3147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-20 6.34E-17 5.30E-20 4.86E-19 65 1271 "ABAT,ZFYVE27,LDLRAD3,MDM4,WAC,SNX30,TOMM40L,MOBP,FOXG1,ITSN1,APBB1,SHTN1,MSR1,SLN,USP33,SON,WDTC1,TNIK,KIF21B,GAD2,INKA2,RGL1,KIRREL3,SLCO1C1,RHBDL3,LUZP2,NEU4,ZEB1,TMEM151B,ADAMTS8,CYB561A3,GUCY1A1,DAAM2,PADI2,TPM4,PDE2A,ZMYND8,ADGRG1,ASIC3,BEST1,NECAB2,ATRNL1,SDC3,KIAA1755,USP54,EDRF1,NOS1AP,DNAJC6,KCNC1,SV2A,KCNK2,PEX5,SNX27,DLG3,PID1,FAM66C,C12orf4,RASGRF1,DTNA,RTN4,NUP214,RFX4,VANGL2,RAVER2,EPB41" MicroRNA hsa-miR-103:PITA hsa-miR-103:PITA_TOP PITA 1.18E-20 6.41E-17 5.34E-20 4.90E-19 37 395 "ASIC1,SYNDIG1,CLIP1,SLITRK1,GALNT13,SCN3A,SEMA6A,ANK1,ITSN1,SH3GL2,PPM1E,NLGN1,SLC1A2,ARHGAP5,SLC8A2,SMARCE1,PHYHIPL,DCAF5,NFIA,VAMP1,ADGRL3,TGFBR3,DCLK1,TPD52,PDE3B,PRMT8,CHRM1,CAMKV,NSD2,FAT3,POU3F2,PPP2R5C,JAKMIP2,PID1,GOPC,BSDC1,ST8SIA3" MicroRNA hsa-miR-107:PITA hsa-miR-107:PITA_TOP PITA 1.18E-20 6.41E-17 5.34E-20 4.90E-19 37 395 "ASIC1,SYNDIG1,CLIP1,SLITRK1,GALNT13,SCN3A,SEMA6A,ANK1,ITSN1,SH3GL2,PPM1E,NLGN1,SLC1A2,ARHGAP5,SLC8A2,SMARCE1,PHYHIPL,DCAF5,NFIA,VAMP1,ADGRL3,TGFBR3,DCLK1,TPD52,PDE3B,PRMT8,CHRM1,CAMKV,NSD2,FAT3,POU3F2,PPP2R5C,JAKMIP2,PID1,GOPC,BSDC1,ST8SIA3" MicroRNA hsa-miR-3137:mirSVR_highEffct hsa-miR-3137:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-20 6.63E-17 5.52E-20 5.07E-19 47 669 "ADAR,FCGR1A,SNX32,ASIC4,HPCAL4,ERICH3,PKP4,APC,ZNF365,SORCS3,DKK3,MYT1L,KIF21B,ADAM15,GNAS,CAMTA1,ANO4,CACNB2,CLEC9A,VSTM2A,GRIA2,GRIA4,TGFBR3,INA,GUCY1A2,TPD52,CIART,TMEFF2,SEMA5B,ANLN,A2ML1,NXPH1,CHD1L,CRLS1,ATRNL1,PLPP4,IGSF1,PTHLH,KCNA4,PTPRD,PLPPR4,KCNJ10,PEX5,TMEM255A,ABI1,ATL1,SEC61A2" MicroRNA hsa-miR-4315:mirSVR_lowEffct hsa-miR-4315:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-20 6.68E-17 5.56E-20 5.10E-19 52 824 "PAQR6,CSMD2,WLS,SLITRK1,ADD3,WAC,GOLGA7B,ELMOD1,SFPQ,SGIP1,DOCK10,CAPRIN2,RCOR3,NCAM1,BCL2L2,INKA2,NEUROD1,POPDC3,TBX15,NPPA,CACNB2,TCF7L2,GRIA2,GRIA4,GRIN1,OMG,LINC00839,LGI1,LRTM2,MS4A7,TMEFF2,NXPH1,CRMP1,SNCAIP,KCNT2,ATRNL1,PRKACB,CTNND2,MAPK10,DPYSL5,TUBB2B,ZNF385B,PRDM2,KCNC1,RABGAP1L,KCNK1,CAB39L,FAM13C,SLC6A15,SSPN,SLC4A10,UEVLD" MicroRNA hsa-miR-494-3p:TargetScan hsa-miR-494-3p TargetScan 1.24E-20 6.72E-17 5.59E-20 5.12E-19 39 446 "MDM4,ADARB2,DSCAML1,KLRC4,GPR158,APC,LRRC4C,ARHGAP5,NSG2,NRG3,B3GALT2,NMNAT2,NPAS3,PSD3,GRIK2,GRIK3,OPCML,LEFTY2,GUCY1A2,DCLK1,ARHGAP19,LRTM2,CADM1,NEGR1,PRKAB2,MAPK10,ANKS1B,JAKMIP2,AK5,KCNK1,KIF2A,RAB5B,RASGRF1,DBX2,RPRD1A,LMO1,ABI2,EN2,RCAN2" MicroRNA hsa-miR-7:mirSVR_highEffct hsa-miR-7:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.24E-20 6.72E-17 5.59E-20 5.12E-19 59 1058 "SDE2,ACER3,MEG3,CSMD3,WAC,TOMM40L,SEMA6A,MOG,SGIP1,ITSN1,GPAM,PAAF1,ARHGAP5,SPHKAP,SLIT1,NAXD,CAPRIN2,ASTN1,RCOR3,PHYHIPL,ATP2B2,KIF1B,CLASP2,GLS,VAMP1,ASTN2,ROBO3,GOLGB1,ANO4,LRIT2,TCF12,SYT6,P2RX7,PAX6,LGI1,MAGI1,PDE4B,MS4A7,A2ML1,ST8SIA5,SPATA6,CRLS1,KCNT2,ATRNL1,FMN2,CMTM5,USP54,CTNND1,NRSN1,EDRF1,ZBTB16,MAGI2,KCNMA1,RAB5B,FAM66C,DTNA,ABCC9,SLC6A15,ATL1" MicroRNA hsa-miR-873:mirSVR_highEffct hsa-miR-873:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-20 6.95E-17 5.77E-20 5.30E-19 57 990 "SDE2,MBP,RTN3,MEG3,NLGN4X,TOMM40L,LRRTM4,LRRC7,FHL1,ELMOD1,BCAN,TACC2,MSR1,SLC8A3,ATM,NRG3,ZSWIM8,NASP,NDUFA5,RGL1,NEUROD1,ARHGEF7,GLS,ZNF638,ADGRL3,CACNB2,ZEB1,GRIK2,ZFP91,PAH,HRH3,CASC2,HNRNPK,CADM1,ZFYVE9,ST8SIA5,COL9A2,ACBD5,CNRIP1,CHD1L,KCNT2,ATRNL1,PLPP4,USP54,NRSN1,MASP1,CA10,ELMO1,PRDM2,KCNA2,DLG2,DNAH9,BSDC1,NUP214,RGS7,SEC61A2,BSCL2" MicroRNA hsa-miR-365*:mirSVR_lowEffct hsa-miR-365*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-20 7.23E-17 6.00E-20 5.50E-19 56 957 "ZFYVE27,MAP6,MBP,ACTN2,GALNT13,ADD3,PNMA8B,SORCS1,TUBB4A,AMER2,NLGN4X,LINC00461,FHL1,FOXG1,TRIM46,ERICH3,RASA3,ASPH,SORCS3,NRG3,WDTC1,CPLX2,NFASC,PHLDB1,ARHGEF7,KLHL4,NRGN,AZIN2,GRIA4,GPR88,P2RX7,TLL2,PAH,PTGDR2,PDYN,BEST3,ASIC3,CHRM1,FLRT1,PTPA,SNCAIP,TENM4,OSBPL3,PROX1,TOX,SIRPA,HP1BP3,KCNJ9,DLG3,SLC17A6,SLC25A18,RASGRF1,DTNA,BSDC1,SSPN,CBLN2" MicroRNA hsa-miR-30b*:mirSVR_highEffct hsa-miR-30b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-20 7.96E-17 6.60E-20 6.06E-19 56 959 "MAG,FAM43B,ATAT1,FOXG1,ERICH3,SH3GL2,GPAM,SYBU,ZNF365,MIER1,SLC1A7,BCO1,LRRC55,SCMH1,CGREF1,SOX5,TTLL9,NPAS3,NASP,GFAP,ARHGEF7,VAMP1,ACSL6,CACNB2,LINC00839,AIFM1,FNDC5,CADM1,A2ML1,PMP2,BTF3L4,NECAB2,CNRIP1,SNCAIP,CSF3R,MICAL2,CMTM5,PRKCG,PLPP4,PRKCZ,USP54,FGFR1OP2,ANKS1B,ELMO1,NTM,KCNJ11,DLG2,KLRC3,TMEM255A,DTNA,NUP214,RFX4,PHC2,ABI2,VWA5A,SLC4A10" MicroRNA hsa-miR-136*:mirSVR_lowEffct hsa-miR-136*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.69E-20 9.16E-17 7.59E-20 6.96E-19 51 798 "SRARP,MBP,ADGRV1,CLIP1,RXRG,KIAA1109,LRRC7,ANK2,PKP4,SH3GL2,BCAS1,ASPH,SLN,SORCS3,ATP2B2,NDUFA5,SLCO1C1,ARHGEF7,KAZN,ADGRL3,CACNA1A,ZEB1,VXN,VSTM2A,PCDH9,MAGI1,PDE4B,HMGB1,ZBED5,TMEFF2,SEMA5B,CNTN1,IFFO1,RNF14,VCAN,PHACTR3,PRKCZ,CTNND2,WBP1L,CADM2,KCNC1,C1orf109,NTM,KLRC3,FAM13C,DTNA,SLC6A15,TTLL7,ABI2,CBLN2,EPB41L1" MicroRNA hsa-miR-4298:mirSVR_highEffct hsa-miR-4298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-20 9.45E-17 7.82E-20 7.18E-19 50 767 "RTN3,KLHL32,GALNT13,ADD3,LRRTM4,LINC00461,ACTL6B,MOBP,NTNG1,MAGI3,SLITRK3,SYBU,ATM,ATP2B2,AHCYL1,ARPP21,KIF1B,ADGRB2,NELL1,GANAB,SEPT3,ARHGEF7,VAMP1,ZNF638,LUZP2,PRUNE2,ACSL6,GRIA2,CYB561A3,MAEL,PCDH9,TPM3,BEST3,TMEFF2,DUSP26,COL9A2,SLC36A4,CHD1L,MED1,SDC3,KIAA1755,LRRTM3,OCIAD1,SNX27,PYGM,C12orf4,ABI1,GNE,DTNA,ABCC9" MicroRNA hsa-miR-4263:mirSVR_highEffct hsa-miR-4263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-20 9.76E-17 8.07E-20 7.41E-19 64 1245 "LGR4,RTN3,ADGRV1,ARID1A,RTKN,ERMN,LINC00461,LRRC7,ELMOD1,MOBP,ERICH3,ANK2,ANK3,SH3GL2,NTNG1,MAGI3,MSR1,MSRA,CCDC88A,PDE8B,NRG3,CAB39,NEK6,CLASP2,ZNF302,NEUROD1,GLS,DCLK2,CAMTA1,PRUNE2,ZEB1,PTBP2,CAMK2G,SYT6,RFFL,GPR88,KCNK10,HPS5,C1orf94,TPD52,BEST3,CASC2,NRXN1,MEAF6,BTF3L4,NSD2,MFSD4A,SNCAIP,KCNT2,NCAN,DZIP3,USP54,SYTL2,CA10,PTHLH,OLFM3,OLIG1,PID1,TMEM255A,FAM66C,PARP11,SEC61A2,ARHGAP12,ELAVL4" MicroRNA hsa-miR-452:PITA hsa-miR-452:PITA_TOP PITA 1.84E-20 9.95E-17 8.23E-20 7.55E-19 39 451 "EPS8,LDLRAD3,CSMD3,ADD3,NLGN4X,HPCAL4,MIER1,SLC8A3,SNAP25,PHYHIPL,SON,MYT1L,CAB39,SALL3,ERBIN,GFRA1,GPM6A,CAMK2G,GRM3,MAEL,C11orf49,BTF3L4,NSD2,FAT3,MED1,PPP2R5C,FMN2,PKN2,CADM2,HP1BP3,KCNK2,TMEM255A,SLC17A6,ABI1,ZYG11B,RBM12,RAVER2,SLC4A10,EPB41L1" MicroRNA hsa-miR-1265:mirSVR_highEffct hsa-miR-1265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-20 1.00E-16 8.29E-20 7.60E-19 54 897 "ABAT,ACER3,RCSD1,FAM43B,ATAT1,WLS,RTKN,CSMD3,SCN3A,MOG,ITSN1,PKP4,NLGN1,RUFY2,SLC8A3,SORCS3,NRG3,SON,NELL1,GANAB,GNAS,ADGRL3,GOLGB1,ANO4,DDR1,PTBP2,NUDT21,CAMK2A,CECR2,VXN,GRIA2,CD81,TPM3,PDE1A,HPSE2,SERPINE2,MEAF6,MED1,TENM4,ATRNL1,RIMS4,PLPP4,BRINP3,LRRTM3,CA10,PTHLH,PTPRE,KCNN3,KLRC2,PID1,ATN1,ZYG11B,EPB41L1,BAALC" MicroRNA hsa-miR-3169:mirSVR_highEffct hsa-miR-3169:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-20 1.07E-16 8.85E-20 8.12E-19 47 677 "RBM10,ADGRV1,MDM4,SCN3A,HPCAL4,SGIP1,USP28,PPFIA1,ANXA7,DOCK10,PAAF1,BCO1,CCDC88A,CADPS,SORCS3,RCOR3,B3GAT1,CAB39,NDUFA5,DCAF5,RGL1,ARHGEF7,UNC5D,PTBP2,GRIA2,TGFBR3,HPS5,TPM3,PDE2A,PDYN,BEST1,CHD1L,RNF14,ATRNL1,VCAN,RBPJ,NRSN1,TOX,LRP8,SMG7,DPP6,PAK5,CRTAC1,FGFBP3,ELAVL3,YY1AP1,EPB41L2" MicroRNA hsa-miR-619:mirSVR_highEffct hsa-miR-619:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-20 1.08E-16 8.87E-20 8.14E-19 51 801 "SYT9,ACTN2,MDM4,NDRG2,KLHL32,FOXG1,APC,MAGI3,API5,MIER1,SLC1A7,SCG3,ASPH,SORCS3,EIF4G3,SOX5,NCAM1,LMO3,ERBIN,ACSBG1,TNR,PCDH9,MAGI1,PDE3B,PLEKHB1,CASC2,TLX1,CADM1,A2ML1,CCSER2,BEST1,POU3F2,ETNPPL,SNCAIP,RBPJ,PRKACB,PRKCG,MASP1,PRTFDC1,LRP8,STMN4,ZC3H11A,PTPRD,RABGAP1L,PCDH15,PARP11,C12orf4,GOPC,RBM12,RPRD1A,RAVER2" MicroRNA hsa-miR-20a-5p:Functional MTI Functional MTI miRTarbase 2.23E-20 1.21E-16 9.92E-20 9.11E-19 59 1071 "RBM10,ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,GPAM,USP16,RUFY2,CAPRIN2,GABBR1,SON,EMC1,SALL3,BCL2L2,SMOC1,ARHGEF7,LUZP2,GNAS,CAMTA1,ADGRL3,WWC1,TCF7L2,NUDT21,PSD3,MFSD2A,TPM4,HMGB1,ZFYVE9,CCSER2,BTF3L4,NSD2,ACBD5,FEZ2,PRKACB,KIAA0513,TOMM20,SIRPA,CADM2,CEP170,CSDE1,OCIAD1,PTPRO,KCND3,RABGAP1L,WIPF2,RAB5B,ATG16L1,NUP214,SH3GLB1,RPRD1A,ABI2,ARHGAP12,BSCL2,TMEM100,UEVLD" MicroRNA hsa-miR-502-5p:mirSVR_highEffct hsa-miR-502-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-20 1.22E-16 1.00E-19 9.20E-19 53 868 "SYT9,ADD3,SEMA6A,SGIP1,PAAF1,ZNF365,RUFY2,BRINP2,SMARCE1,ATP1A2,PHYHIPL,KIF1B,NFASC,SLCO1C1,PCDH11X,ADGRL3,ANO4,TBX15,ZEB1,CLEC9A,GRIA4,RFFL,GPR88,CYB561A3,INA,TJP1,AIFM1,MAGI1,ZNF384,LINC01102,CASC2,KIAA1549L,A2ML1,FLRT1,MED1,RNF14,SNCAIP,PRKCZ,PTCH1,PTPRD,SMG7,PTPRE,KCNK1,PCDH15,FAM66C,PARP11,DTNA,CAMK1G,JMJD1C,RGS10,FAM135B,PHC2,ELAVL3" MicroRNA "TGGTGCT,MIR-29C:MSigDB" "TGGTGCT,MIR-29C:MSigDB" MSigDB 2.26E-20 1.22E-16 1.00E-19 9.20E-19 40 480 "DPF1,MAP6,ASIC1,KCNIP2,SFPQ,ANK3,PPM1E,GPAM,DGKD,SLC1A2,ASPH,MIR4697HG,NASP,NFASC,C11orf87,RND1,NFIA,CAMTA1,EML4,CAMK2G,ZFP91,CDC42,NLGN3,CCSER2,IFFO1,NSD2,PRKAB2,CTNND1,FAM131B,PLPPR5,TUBB2B,PTHLH,SRGAP3,KCNMA1,NAV2,PEX5,TMEM255A,FAM57B,GOPC,RET" MicroRNA "TGGTGCT,MIR-29B:MSigDB" "TGGTGCT,MIR-29B:MSigDB" MSigDB 2.26E-20 1.22E-16 1.00E-19 9.20E-19 40 480 "DPF1,MAP6,ASIC1,KCNIP2,SFPQ,ANK3,PPM1E,GPAM,DGKD,SLC1A2,ASPH,MIR4697HG,NASP,NFASC,C11orf87,RND1,NFIA,CAMTA1,EML4,CAMK2G,ZFP91,CDC42,NLGN3,CCSER2,IFFO1,NSD2,PRKAB2,CTNND1,FAM131B,PLPPR5,TUBB2B,PTHLH,SRGAP3,KCNMA1,NAV2,PEX5,TMEM255A,FAM57B,GOPC,RET" MicroRNA "TGGTGCT,MIR-29A:MSigDB" "TGGTGCT,MIR-29A:MSigDB" MSigDB 2.26E-20 1.22E-16 1.00E-19 9.20E-19 40 480 "DPF1,MAP6,ASIC1,KCNIP2,SFPQ,ANK3,PPM1E,GPAM,DGKD,SLC1A2,ASPH,MIR4697HG,NASP,NFASC,C11orf87,RND1,NFIA,CAMTA1,EML4,CAMK2G,ZFP91,CDC42,NLGN3,CCSER2,IFFO1,NSD2,PRKAB2,CTNND1,FAM131B,PLPPR5,TUBB2B,PTHLH,SRGAP3,KCNMA1,NAV2,PEX5,TMEM255A,FAM57B,GOPC,RET" MicroRNA hsa-miR-520g:PITA hsa-miR-520g:PITA_TOP PITA 2.27E-20 1.23E-16 1.01E-19 9.23E-19 41 507 "SDE2,CSMD3,NLGN4X,MAGI3,SLC1A2,MIER1,EIF4G3,ATP2B2,ADGRB2,NPAS3,NCAM1,NELL1,RGL1,NHLH1,CAMSAP2,TCF12,ZFP91,RBFOX2,ANLN,C11orf49,PRRX1,ACBD5,POU3F2,PNKD,PKN2,CTNND2,DPYSL5,LRRTM3,CA10,CSDE1,MAGI2,KCNJ10,DLG2,WIPF2,RAB5B,DNM2,DBX2,RGS7,SEC61A2,EN2,EPB41" MicroRNA hsa-miR-520h:PITA hsa-miR-520h:PITA_TOP PITA 2.27E-20 1.23E-16 1.01E-19 9.23E-19 41 507 "SDE2,CSMD3,NLGN4X,MAGI3,SLC1A2,MIER1,EIF4G3,ATP2B2,ADGRB2,NPAS3,NCAM1,NELL1,RGL1,NHLH1,CAMSAP2,TCF12,ZFP91,RBFOX2,ANLN,C11orf49,PRRX1,ACBD5,POU3F2,PNKD,PKN2,CTNND2,DPYSL5,LRRTM3,CA10,CSDE1,MAGI2,KCNJ10,DLG2,WIPF2,RAB5B,DNM2,DBX2,RGS7,SEC61A2,EN2,EPB41" MicroRNA hsa-miR-128:PITA hsa-miR-128:PITA_TOP PITA 2.27E-20 1.23E-16 1.01E-19 9.23E-19 41 507 "SDE2,SYNDIG1,ADCY2,AMER2,PPM1E,APBA2,NTNG1,GPAM,CCDC88A,PDE8B,RCOR3,MEGF11,GAD2,NCAM1,NEUROD1,VAMP1,PTPN5,TMEM25,MFSD2A,KCNK10,TUB,DLGAP3,KIAA1549L,CCDC136,CABP1,MED1,RGS6,NCAN,CTNND2,WBP1L,DPYSL5,CA10,KCNA1,SV2A,KCNK2,DLG2,RTN4,RET,VANGL2,ARHGAP12,RCAN2" MicroRNA hsa-miR-888*:mirSVR_lowEffct hsa-miR-888*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-20 1.27E-16 1.04E-19 9.53E-19 73 1594 "ACER3,MAP6,MBP,MDM4,ADAR,KLHL32,GALNT13,CDC7,ERMN,TESK2,SCN3A,BCAR3,NTNG1,GPAM,SORBS1,ST3GAL3,JAKMIP3,AQP4,ZNF365,MADD,ARFGAP2,SLC8A3,DACH2,ASCL1,CAPRIN2,ASPH,SLN,MYT1L,ALDH1L1,NELL1,ADHFE1,MMD2,DDR1,TCF12,HAP1,DDR2,NUCB1,GRIA2,GRID1,GPR88,ATP13A2,TF,MFSD2A,GUCY1A2,P2RX7,HPS5,DCLK1,PTGDR2,ZMYND8,FNDC5,ANO5,FAM181B,NSD2,CHD5,NCAN,RBPJ,PRKAB2,CMTM5,MAPK10,NOS1AP,TOX,KIAA0513,WBP1L,ANKS1B,DNAJC6,ITGAV,PTPRE,NTM,AK5,OLIG1,GOPC,ABI2,UEVLD" MicroRNA hsa-miR-639:mirSVR_lowEffct hsa-miR-639:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-20 1.32E-16 1.08E-19 9.90E-19 41 508 "SERPINA3,ZFYVE27,RCSD1,ECSIT,LDLRAD3,LRRTM4,FGF14,SEMA6A,ST3GAL3,ZNF365,KIAA1614,SFMBT2,SLCO1A2,LGI3,ARFGAP1,ATP1A2,ZSWIM8,LMO3,GNAS,DDHD2,SYT6,CYB561A3,LINC00839,SEZ6L,MAGI1,ASIC3,CASC2,NLGN3,PLXNB3,PPP2R5C,SNCAIP,NOS1AP,KLK6,PRDM2,PTPRE,SRGAP3,GPR61,ABI2,PRRT4,EPB41L2,RCAN2" MicroRNA hsa-miR-187*:mirSVR_highEffct hsa-miR-187*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-20 1.47E-16 1.20E-19 1.10E-18 52 839 "ATAT1,WAC,LINC00461,KIAA1109,LRRC7,FGF14,BBOX1,AMPH,ANXA7,SHTN1,MIER1,ASPH,SNAP25,ATM,MYT1L,SALL3,LMO3,SMOC1,PCDH11X,MMD2,GPM6A,DDR1,TCF7L2,GRIA2,PCDH9,DCLK1,TPM3,CASC2,NOMO2,PIK3CD,BTF3L4,CP,PPP2R5C,PPP3CB,FEZ2,RBPJ,PUM1,BRINP3,TOX,ZNF385B,CADM2,PRDM2,MAGI2,PTPRZ1,BSDC1,SLC6A15,RGS7,RGS10,PHC2,ARHGAP12,RAVER2,C2orf80" MicroRNA hsa-miR-3168:mirSVR_highEffct hsa-miR-3168:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-20 1.48E-16 1.21E-19 1.11E-18 56 972 "RTN3,ARID1A,DSCAML1,GALNT13,ADD3,SLC44A5,SGIP1,GPAM,CGREF1,TAGLN3,ASPH,EIF4G3,SCN3B,B3GALT2,SALL3,DNER,NCAM1,LMO3,PCDH11X,ADGRL3,PRUNE2,EML4,VSTM2A,GRIA4,GPR88,GRM3,CRB1,LEFTY2,PDYN,GPR37L1,BEST3,TJP2,ATRNL1,NCAN,PLD5,MAPK8,EDRF1,LRRTM3,DNAJC6,MAGI2,PTPRE,PLPPR4,NTM,KCNK1,PCDH15,DLG2,WIPF2,GNE,FAM13C,RTN4,ZYG11B,RPRD1A,GPR61,CBLN2,YY1AP1,EPB41L2" MicroRNA hsa-miR-375:mirSVR_lowEffct hsa-miR-375:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.86E-20 1.55E-16 1.26E-19 1.16E-18 56 973 "RABEPK,SYT9,KLHL32,SORCS1,GRAMD1B,AGT,KIAA1109,ITSN1,PKP4,CCDC80,AQP4,RUFY2,PDE8B,CAPRIN2,CCDC181,PHYHIPL,WDTC1,NCAM1,C11orf87,ERBIN,NEUROD1,VAMP1,PCDH11X,CAMTA1,PSRC1,ANO4,GPM6B,ZEB1,TCF12,GRIA2,GRIA4,GRIK2,GRIK3,TF,ZFP91,MAEL,IGSF21,MAGI1,NTSR2,NLGN3,NRXN1,CNRIP1,CP,DZIP3,RAB39A,PLD5,PUM1,PLPPR5,ZNF385B,PTCH1,PTPRE,SLC17A6,ZYG11B,RGS7,RPRD1A,VWA5A" MicroRNA hsa-miR-204:PITA hsa-miR-204:PITA_TOP PITA 2.91E-20 1.58E-16 1.29E-19 1.18E-18 38 431 "TTYH1,LGR4,CLIP1,SEMA6A,SGIP1,PPM1E,ST3GAL3,ARHGAP5,YPEL4,RCOR3,MYT1L,ZCCHC24,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,CAMTA1,GPM6A,TCF12,OPCML,ZFP91,PCDH9,RBFOX2,PRRX1,ACBD5,POU3F2,CHD5,PTCH1,PRDM2,KCNA1,PTPRD,KCNMA1,PID1,TMEM255A,DNM2,SEC61A2,ELAVL3" MicroRNA hsa-miR-211:PITA hsa-miR-211:PITA_TOP PITA 2.91E-20 1.58E-16 1.29E-19 1.18E-18 38 431 "TTYH1,LGR4,CLIP1,SEMA6A,SGIP1,PPM1E,ST3GAL3,ARHGAP5,YPEL4,RCOR3,MYT1L,ZCCHC24,LMO3,BCL2L2,SMOC1,ERBIN,RGL1,CAMTA1,GPM6A,TCF12,OPCML,ZFP91,PCDH9,RBFOX2,PRRX1,ACBD5,POU3F2,CHD5,PTCH1,PRDM2,KCNA1,PTPRD,KCNMA1,PID1,TMEM255A,DNM2,SEC61A2,ELAVL3" MicroRNA hsa-miR-548m:PITA hsa-miR-548m:PITA_TOP PITA 2.93E-20 1.59E-16 1.29E-19 1.18E-18 39 457 "ACER3,SYT9,CLIP1,DSCAML1,SLITRK1,SOX6,PPM1E,MAGI3,API5,SHTN1,AQP4,CCDC88A,SORCS3,RCOR3,PALLD,SON,RGL1,NEUROD1,CAMSAP2,ANO4,GPM6A,ATF7,GRM3,TJP1,LGI1,TPM3,MAGI1,PDE2A,CADM1,RBPJ,KIAA0408,DNAJC6,CEP170,PTPRD,SNX27,KIF2A,DSCAM,PAK5,RBM12" MicroRNA hsa-miR-151-5p:mirSVR_lowEffct hsa-miR-151-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-20 1.69E-16 1.38E-19 1.26E-18 45 625 "RTN3,KCNIP2,CSMD3,TOMM40L,SCN3A,SEMA6A,UNC79,MOG,AMPH,ITSN1,NTNG1,ST3GAL3,CADPS,ASCL1,TAGLN3,SORCS3,ATM,DKK3,WDTC1,NMNAT2,GNAS,LILRA1,GRIA2,PTGDR2,NTSR2,ASIC3,FAAP20,RAB39A,PLPP4,IGSF1,MAPK10,PLPPR5,PTCH1,ELMO1,PRDM2,CSDE1,MED24,PTPRD,PTPRE,KCNC1,NAV2,HS3ST4,DNM2,VANGL2,CACNG7" MicroRNA hsa-miR-454*:mirSVR_lowEffct hsa-miR-454*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-20 1.74E-16 1.41E-19 1.30E-18 51 810 "SDE2,ASIC1,CDHR1,IL17D,KCNIP2,CSMD3,ADAR,HOGA1,ASIC4,UNC79,DOCK10,ST3GAL3,ARHGAP5,GPR153,SCG3,SNAP25,MYT1L,NMNAT2,BCL2L2,RCOR2,ZNF638,CAMTA1,MYRF,PTBP2,GRIK2,OPCML,TMEM9,CDC42,PDE4B,LINC01102,FNDC5,PFKFB3,CASC2,FTO,PMP2,BTF3L4,PRRX1,CHD1L,PPP2R5C,FMN2,EDRF1,MASP1,RIMS3,DPYSL5,PCDH15,SLC6A15,CAMK1G,RET,JMJD1C,ELAVL4,BAALC" MicroRNA hsa-miR-24-3p:TargetScan hsa-miR-24-3p TargetScan 3.52E-20 1.91E-16 1.55E-19 1.42E-18 43 569 "ADCYAP1R1,ADD3,GRAMD1B,SCN3A,ANK3,GAS7,CACHD1,KIAA1614,KIF21B,NEK6,NFASC,BCL2L2,NEUROD1,ACSBG1,SEMA4A,ACSL6,CACNA1E,HAP1,NUDT21,EML4,GRIK3,REPS2,ARHGAP19,MAGI1,IGFN1,FNDC5,KIAA1549L,CHD5,PROX1,PMEPA1,PTPRD,KCNK2,NAV2,KIF2A,RAB3IL1,RAB5B,GNE,DTNA,PIANP,GPR61,ABI2,FGFBP3,EPB41L1" MicroRNA hsa-miR-654-3p:mirSVR_highEffct hsa-miR-654-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-20 1.91E-16 1.55E-19 1.42E-18 54 910 "TMEM74,SYNDIG1,ADCY2,SLITRK1,FCGR1A,MOBP,SORBS1,MIER1,MSR1,SLC8A3,SCG3,CAPRIN2,ASPH,ILDR2,AHCYL1,KIF1B,NCAM1,STOX1,RCOR2,NELL1,GLS,ZNF638,UNC5D,ADGRL3,ZEB1,RFFL,GRIK2,OLR1,CCKBR,TJP1,CDC42,CDH10,HPSE2,NRXN1,BTF3L4,PACSIN1,CP,USP54,PLPPR5,ITGAV,CA10,CADM2,ELMO1,BLOC1S6,NTM,PCDH15,KCNMA1,SNX27,WIPF2,KLRC2,PARP11,ZYG11B,TTLL7,SLC4A10" MicroRNA hsa-miR-4273:mirSVR_highEffct hsa-miR-4273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-20 2.01E-16 1.63E-19 1.50E-18 60 1118 "MBP,SYT9,ATAT1,MDM4,WAC,TOMM40L,AGT,MOBP,FOXG1,FOXM1,PKP4,SLITRK3,SORBS1,SLC8A3,ASPH,SORCS3,ATM,EIF4G3,PALLD,ILDR2,GAD2,AHCYL1,TTLL9,RGL1,NEUROD1,PCDH11X,NKX2-2,CAMTA1,TMEM136,TBX15,TCF12,CRB1,GUCY1A2,CDH8,PDE3B,CA14,JAM2,NRXN1,NEGR1,BTF3L4,SLC36A4,ACBD5,CNRIP1,SNCAIP,DOCK7,PKN2,MASP1,BDNF-AS,OLFM3,AK5,KCNMA1,KCNN3,SLC17A6,PAK5,RGR,INSYN2,RBM12,ABI2,CBLN2,SEZ6" MicroRNA hsa-miR-629*:mirSVR_highEffct hsa-miR-629*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-20 2.02E-16 1.63E-19 1.50E-18 64 1263 "RABEPK,LOC100128239,ARID1A,MDM4,KCNIP2,KLHL32,GALNT13,ERMN,NLGN4X,TOMM40L,SLC30A10,HPCAL4,FOXG1,CDC42BPA,ITSN1,GPAM,PAAF1,ZNF365,RPH3A,SLC14A1,DACH2,SORCS3,TMEM108,NRG3,ZSWIM8,ARPP21,EMC1,FXYD6,GLS,PCDH11X,ZNF638,POPDC3,GOLGB1,KLHL4,TBX15,CACNA1A,WSCD1,ZEB1,TCF12,RFFL,TIE1,TPM3,PDYN,ZMYND8,NLGN3,NEGR1,DNAJC12,POU3F2,CHD1L,RGS6,PRKACB,FMN2,PKN2,ECE2,ZBTB16,PTHLH,SMG7,SLC6A15,ZYG11B,RET,USH1C,RFX4,SLC4A10,OLIG2" MicroRNA hsa-miR-298:PITA hsa-miR-298:PITA_TOP PITA 3.83E-20 2.07E-16 1.68E-19 1.54E-18 31 269 "CSMD3,NDRG2,SCN3A,SEMA6A,FHL1,ANK1,CCDC88A,CSPG5,LGI3,MYBPC1,AHCYL1,LHFPL4,NCAM1,BCL2L2,ADGRL3,ZEB1,TCF12,HAP1,HRH3,PDE4B,MED1,SF1,RIMS3,KCNA1,HS3ST4,WIPF2,RAB5B,RALGDS,ELAVL3,EN2,RCAN2" MicroRNA "CAGTGTT,MIR-200A:MSigDB" "CAGTGTT,MIR-200A:MSigDB" MSigDB 3.96E-20 2.14E-16 1.73E-19 1.59E-18 32 291 "ATAT1,SEMA6A,ELMOD1,SFPQ,ITSN1,PPM1E,ST3GAL3,SLC6A9,PHYHIPL,SON,MYT1L,SOX5,ZCCHC24,NMNAT2,NFASC,CLASP2,SYT4,CAMSAP2,GPM6B,TCF12,PCDH8,PCDH9,ACOT7,NRXN1,NSD2,PRKACB,CTNND2,KIAA0408,PEX5,SNX27,SLC17A6,ATL1" MicroRNA "CAGTGTT,MIR-141:MSigDB" "CAGTGTT,MIR-141:MSigDB" MSigDB 3.96E-20 2.14E-16 1.73E-19 1.59E-18 32 291 "ATAT1,SEMA6A,ELMOD1,SFPQ,ITSN1,PPM1E,ST3GAL3,SLC6A9,PHYHIPL,SON,MYT1L,SOX5,ZCCHC24,NMNAT2,NFASC,CLASP2,SYT4,CAMSAP2,GPM6B,TCF12,PCDH8,PCDH9,ACOT7,NRXN1,NSD2,PRKACB,CTNND2,KIAA0408,PEX5,SNX27,SLC17A6,ATL1" MicroRNA hsa-miR-557:mirSVR_highEffct hsa-miR-557:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.17E-20 2.26E-16 1.82E-19 1.67E-18 56 981 "FAM43B,ERMN,SCN3A,LRRTM4,BCAR3,FHL1,UNC79,MOG,SELL,AMPH,ANK2,USP28,CNIH2,PPFIA1,SESN3,SLC1A6,SMARCE1,RCOR3,ATP2B2,B3GALT2,TTLL9,NEUROD1,GLS,NKX2-2,ANO4,CACNB2,GRIK2,TMEM257,PAX6,PCDH9,RBFOX2,PCSK2,MAGI1,HNRNPK,NRXN1,MEAF6,BTF3L4,DZIP3,FMN2,PRKCZ,LRRTM3,OLFM3,PTPRD,PTPRO,KCNJ9,KCNK1,PLEKHB2,ABI1,ATN1,DSCAM,DBX2,ABCC9,GPR61,FGFBP3,SLC4A10,ELAVL4" MicroRNA hsa-miR-129-5p:TargetScan hsa-miR-129-5p TargetScan 4.31E-20 2.33E-16 1.88E-19 1.73E-18 41 516 "CSMD2,KLHL32,ANK3,ITSN1,APC,JAKMIP3,LRRC4C,RPH3A,CCDC88A,EIF4G3,MYT1L,CAB39,JPH4,ADHFE1,FAM168A,ACSBG1,NFIA,CACNA1A,PSD3,OPCML,PAX6,PCDH8,RBFOX2,FNDC5,GPR37L1,HMGB1,HNRNPK,CADM1,NRXN1,NRXN2,ANKS1B,PMEPA1,PTPRZ1,KCNK1,FAM135B,ARHGEF10L,FGFBP3,ELAVL3,ELAVL4,OLIG2,PLEKHO1" MicroRNA hsa-miR-922:PITA hsa-miR-922:PITA_TOP PITA 4.53E-20 2.46E-16 1.98E-19 1.82E-18 36 386 "ASIC1,SLITRK1,SCN3A,SCN4B,SEMA6A,ANK3,API5,CSPG5,LGI3,CAB39,LHFPL4,LMO3,DCAF5,CAMTA1,HAP1,CAMK2G,GRIA2,TIE1,CELF3,CADM1,SEMA5B,NOMO2,PRRX1,MED1,SF1,OSBPL3,PKN2,PSD,SRGAP3,KCNK2,RAB5B,VANGL2,RAVER2,ELAVL3,EN2,EPB41" MicroRNA hsa-miR-3192:mirSVR_highEffct hsa-miR-3192:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.77E-20 2.58E-16 2.08E-19 1.91E-18 52 850 "RTN3,RTKN,ADORA3,FGF14,CDC42BPA,PI16,API5,MADD,LRRC55,ARFGAP2,SOX5,AHCYL1,LMO3,ALDH1L1,KIRREL3,AJAP1,MYRF,PRUNE2,CACNB2,GRIA2,OLR1,LINC00839,TMEM257,LGI1,ZNF384,PDYN,FNDC5,HPSE2,KIAA1549L,CNTN1,MEAF6,BTF3L4,NXPH1,MED1,SNCAIP,PRKCZ,CTNND2,FGFR1OP2,TOMM20,PSMD13,PLPPR1,SMG7,KCNMA1,WIPF2,DBX2,L1CAM,RFX4,ZNF248,RNF220,SIDT2,ABI2,PRRT4" MicroRNA hsa-miR-206:TargetScan hsa-miR-206 TargetScan 4.83E-20 2.62E-16 2.10E-19 1.93E-18 45 632 "RABEPK,RTN3,ADAR,GPR158,MOG,DGKZ,MIER1,ASPH,CPLX2,NPAS3,BCL2L2,FGF17,FAM168A,GLS,MMD2,NUDT21,EML4,RFFL,GUCY1A2,PAX6,CDC42,PIRT,HNRNPK,GDAP1L1,NMT2,MED1,RNF14,RIMS4,PRKACB,CTNND2,ELMO1,HP1BP3,MAGI2,PTPRD,KCND3,RABGAP1L,DLG2,KIF2A,GNE,PHC2,ABI2,BSCL2,EPB41L1,EPB41L2,RCAN2" MicroRNA hsa-miR-1-3p:TargetScan hsa-miR-1-3p TargetScan 4.83E-20 2.62E-16 2.10E-19 1.93E-18 45 632 "RABEPK,RTN3,ADAR,GPR158,MOG,DGKZ,MIER1,ASPH,CPLX2,NPAS3,BCL2L2,FGF17,FAM168A,GLS,MMD2,NUDT21,EML4,RFFL,GUCY1A2,PAX6,CDC42,PIRT,HNRNPK,GDAP1L1,NMT2,MED1,RNF14,RIMS4,PRKACB,CTNND2,ELMO1,HP1BP3,MAGI2,PTPRD,KCND3,RABGAP1L,DLG2,KIF2A,GNE,PHC2,ABI2,BSCL2,EPB41L1,EPB41L2,RCAN2" MicroRNA hsa-miR-2355:mirSVR_highEffct hsa-miR-2355:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.08E-20 2.75E-16 2.21E-19 2.03E-18 49 755 "MAG,ZFYVE27,LGR4,EYA1,WAC,MOBP,SLITRK3,BCAS1,AQP4,BCO1,NAXD,ASPH,RCOR3,AHCYL1,ARPP21,SALL3,ZNF302,FAM168A,RHBDL3,ROBO3,LRIT2,PTBP2,CECR2,AKNA,LEFTY2,TIE1,SEZ6L,MAGI1,PDE1A,LINC01102,HAPLN2,LRTM2,HNRNPK,PIK3CD,PMP2,RNF14,SPIRE1,SYNC,PRTFDC1,KCNA2,PARD6A,SV2A,DTNA,ZYG11B,RET,RFX4,RLBP1,ELAVL3,TMEM100" MicroRNA hsa-miR-145-5p:TargetScan hsa-miR-145-5p TargetScan 5.18E-20 2.81E-16 2.25E-19 2.07E-18 46 663 "ACHE,LDLRAD3,RTKN,CSMD3,CLIP1,ADD3,FGF14,NTNG1,CCDC80,CACHD1,NLGN1,ATP1A2,FYN,GFRA1,NFIA,OS9,CAMSAP2,MYRF,CACNB2,NUDT21,CECR2,PSD3,MFSD2A,AIFM1,PCDH9,CADM1,NEGR1,FLRT1,CABP1,BTF3L4,PKN2,CTNND1,ELMO1,MAGI2,BLOC1S6,KCNA1,KCNA4,KCNH1,KCNN3,GOPC,DSCAM,RGS7,EFNA3,ABI2,ARHGAP12,ELAVL4" MicroRNA hsa-miR-9:mirSVR_highEffct hsa-miR-9:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.21E-20 2.82E-16 2.26E-19 2.08E-18 67 1384 "CNTNAP3,ARID1A,MDM4,ADD3,SLC44A5,CHST15,TESK2,LRRTM4,UNC79,FOXG1,ERICH3,ANK2,PKP4,APBA2,DOCK10,NTNG1,GPAM,NLGN1,SHTN1,CCDC88A,SLC14A1,ADGRA1,DKK3,WDTC1,ARPP21,TTLL9,KIF1B,NCAM1,GLS,DDHD2,ANO4,CACNB2,PTBP2,GPR88,HPS5,CDH8,LGI1,PCSK2,MAGI1,PIRT,ACOT7,BEST3,JAM2,GDAP1L1,CCSER2,BEST1,PRRX1,FAAP20,POU3F2,PPP2R5C,MICAL2,VCAN,DOCK7,USP54,NRSN1,TOMM20,PLPPR5,JAKMIP2,PCDH15,KCNMA1,KCNN3,ABI1,FAM13C,RET,ABI2,RPE65,EPB41" MicroRNA hsa-miR-187*:mirSVR_lowEffct hsa-miR-187*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.38E-20 2.91E-16 2.33E-19 2.14E-18 68 1423 "PRR5L,ACER3,MBP,RCSD1,IL17D,ARID1A,RTN1,ADCY2,KLRC4,SNX32,UNC79,ELMOD1,FOXG1,CDC42BPA,ITSN1,NTNG1,AQP4,RUFY2,CCDC88A,CGREF1,SMARCE1,KBTBD12,SON,SOX1,ZCCHC24,CAB39,GAD2,NMNAT2,ARPP21,NAP1L2,RAP1GAP2,SPART,C11orf87,AJAP1,SLCO1C1,ARHGEF7,GLS,LUZP2,KAZN,TBX15,GPM6B,TCF12,PTBP2,RFFL,TLL2,PADI2,PLEKHB1,NEGR1,FTO,CNTN1,PRRX1,POU3F2,KCNT2,ARHGEF4,GON4L,PTCH1,PLPPR1,ZC3H11A,OLFM3,KCNK1,SLC17A6,GOPC,PAK5,NUP214,RET,RFX4,JMJD1C,SLC39A12" MicroRNA hsa-miR-194:mirSVR_highEffct hsa-miR-194:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.54E-20 3.00E-16 2.40E-19 2.20E-18 55 953 "ACHE,ACTN2,IL17D,RTN1,ITSN1,PPM1E,APC,NTNG1,JAKMIP3,ZNF365,RUFY2,DACH2,TMEM108,ALDH4A1,ATM,SOX5,NCAM1,LMO3,CLASP2,ADHFE1,NEUROD1,ARHGEF7,SYT4,CAMSAP2,TMEM136,KLHL4,TBX15,NPPA,VSTM2A,GRIA2,GRIA4,ZFP91,CD81,CDC42,LGI1,SERPINE2,ZFYVE9,TJP2,SLC25A27,MICAL1,BTF3L4,PPP3CB,ATRNL1,NCAN,CEP170,MAGI2,PTPRD,PTPRZ1,PCDH15,PARP11,DPP6,RTN4,SLC6A15,CBLN2,ELAVL3" MicroRNA hsa-miR-101*:mirSVR_highEffct hsa-miR-101*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.74E-20 3.11E-16 2.49E-19 2.28E-18 54 920 "ACER3,MAP6,ATAT1,FABP7,PPFIA1,ANXA7,SLITRK3,RUFY2,ARHGAP5,CCDC88A,SLCO1A2,SPHKAP,LGI3,ASPH,SMARCE1,CCDC181,AHCYL1,LMO3,ARHGEF7,GLS,CAMSAP2,UNC5D,PSRC1,GOLGB1,ACSL6,LILRA1,ZEB1,GRID1,INA,ZMYND8,BEST3,MS4A7,ZBED5,MEAF6,SLC36A4,ACBD5,FEZ2,NCAN,PRKACB,DOCK7,CTNND1,GON4L,TOMM20,PLPPR5,PRDM2,LRP8,CEP170,OLFM3,OCIAD1,C1orf109,KCNMA1,DTNA,SLC6A15,YY1AP1" MicroRNA hsa-miR-549:mirSVR_highEffct hsa-miR-549:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.84E-20 3.16E-16 2.53E-19 2.32E-18 52 854 "SDE2,ABAT,MAP6,WLS,SLC25A25,NDRG2,ADD3,FHL1,SLC30A10,FOXG1,AMPH,ASRGL1,MAGI3,DGKD,BCAS1,MIER1,ARHGAP5,SLC8A3,NSG2,ATP1A2,KIF21B,GAD2,ARPP21,SMOC1,GLS,LUZP2,DDHD2,ADGRL3,PRUNE2,SYT6,OLR1,LINC00839,MFSD2A,FBXL16,ZFP91,PAX6,PCDH9,PCSK2,HMGB1,FAAP20,DZIP3,PUM1,SYNC,ITGAV,HP1BP3,COPS7A,PTPRD,KCNMA1,HS3ST4,FAM13C,SLC39A12,RPRD1A" MicroRNA hsa-miR-122:mirSVR_highEffct hsa-miR-122:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.36E-20 3.45E-16 2.75E-19 2.53E-18 44 607 "SYT9,RCSD1,MDM4,KLHL32,RXRG,GALNT13,AMPH,ERICH3,ITSN1,SH3GL2,SLITRK3,BCAN,ZNF365,ARFGAP2,GABBR1,ADGRB2,NPAS3,NDUFA5,NCDN,INKA2,RGL1,LUZP2,DCLK2,UNC5D,GPM6B,LRIT2,GRIA2,LGI1,PCSK2,PLEKHB1,GDAP1L1,CCSER2,TJP2,DNAJC12,CRMP1,CTNND2,MASP1,PTHLH,CNIH3,PRTFDC1,KCNK2,RGR,JMJD1C,RAVER2" MicroRNA hsa-miR-484:mirSVR_highEffct hsa-miR-484:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.79E-20 3.68E-16 2.93E-19 2.69E-18 43 579 "TTYH1,ACHE,RTN3,ERMN,ADORA3,TOMM40L,FGF1,FHL1,TRIM46,ANK1,ST3GAL3,SOX5,ZCCHC24,INKA2,GOLGB1,NUMA1,GRIA4,GRIN1,CYB561A3,CRB1,TGFBR3,MFSD2A,CDK11B,PADI2,MAGI1,FNDC5,DNAJC12,PLXNB3,COL9A2,NXPH1,ACBD5,SNCAIP,NCAN,DOCK7,PRKCG,PKN2,PSMD13,BDNF-AS,PTPRE,RABGAP1L,DNM2,BSDC1,ARHGEF10L" MicroRNA hsa-miR-744:mirSVR_lowEffct hsa-miR-744:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.82E-20 3.69E-16 2.94E-19 2.70E-18 48 729 "ASIC1,SYNDIG1,CEND1,FAM43B,ATAT1,LDLRAD3,TUBB4A,FCGR1A,DRAXIN,TOMM40L,TRIM46,SEMA6C,MAGI3,BCAN,GPR153,NAXD,SNCB,WDTC1,CADM3,SOX10,SALL3,FXYD6,C11orf87,ALDH1L1,RCOR2,CASTOR3,CACNA1E,DDR1,NRGN,GRIA1,USP2,FBXL16,HPSE2,ASIC3,CAMKV,OPALIN,FADS2,PLXNB3,NKAIN4,MICAL2,PRKAB2,CALY,MASP1,KCNK2,PYGM,DNM2,BSDC1,ARHGEF10L" MicroRNA hsa-miR-520c-3p:PITA hsa-miR-520c-3p:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-302a:PITA hsa-miR-302a:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-520d-3p:PITA hsa-miR-520d-3p:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-302b:PITA hsa-miR-302b:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-302c:PITA hsa-miR-302c:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-373:PITA hsa-miR-373:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-520a-3p:PITA hsa-miR-520a-3p:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-302d:PITA hsa-miR-302d:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-302e:PITA hsa-miR-302e:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-520e:PITA hsa-miR-520e:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-372:PITA hsa-miR-372:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-520b:PITA hsa-miR-520b:PITA_TOP PITA 7.03E-20 3.81E-16 3.01E-19 2.76E-18 42 551 "LGR4,SNX30,AMER2,GPR158,MAGI3,SLITRK3,RCOR3,PHYHIPL,ATP2B2,PALLD,MYT1L,NPAS3,LMO3,ERBIN,RGL1,NEUROD1,ARHGEF7,CAMTA1,GPM6A,OPCML,ZFP91,TNS1,PCDH9,DCLK1,SLC25A27,PRRX1,ACBD5,PKN2,TOX,SYNC,SIRPA,CADM2,HP1BP3,RGMA,ZC3H11A,PTPRD,KCNK2,HS3ST4,WIPF2,FAM13C,PAK5,TMEM100" MicroRNA hsa-miR-3188:mirSVR_highEffct hsa-miR-3188:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.15E-20 3.87E-16 3.06E-19 2.80E-18 52 858 "EPS8,SERPINA3,MRVI1,CLIP1,SLC44A5,AGT,ELMOD1,ANK2,ITSN1,GPAM,ST3GAL3,SCG3,SORCS3,SMARCE1,RCOR3,NRG3,PHYHIPL,CAB39,B4GALNT1,KIF1B,ERBIN,ADHFE1,ARHGEF7,KLHL4,PTBP2,NUMA1,GRIA2,GRIA4,TF,INA,CDC42,PDE4B,BEST3,TLX1,GDAP1L1,ANLN,OPALIN,SLC36A4,PTPA,SNCAIP,MICAL2,OSBPL3,NRSN1,SYTL2,CA10,BDNF-AS,COPS7A,MAGI2,PEX5,PAK5,SLC6A15,RBM12" MicroRNA hsa-miR-185*:mirSVR_highEffct hsa-miR-185*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.22E-20 3.91E-16 3.08E-19 2.83E-18 44 609 "ASIC1,EXTL1,ATAT1,TRIM46,PI16,ITSN1,SH3GL2,NTNG1,DGKZ,MADD,SLC14A1,NAXD,SORCS3,RCOR3,PHYHIPL,MEGF11,WDTC1,NFASC,CAMTA1,PSRC1,GOLGB1,MFSD2A,PAH,PRMT8,CHGA,HEPACAM,CCSER2,FTO,C11orf49,BEST1,CSF3R,MICAL2,PKN2,IGSF1,CTNND1,HES5,KCNA2,SMG7,PTPRO,SRGAP3,KCNJ9,NKAIN1,SUSD4,NUP214" MicroRNA hsa-miR-31*:mirSVR_lowEffct hsa-miR-31*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.30E-20 3.96E-16 3.12E-19 2.86E-18 54 925 "TTYH1,EPS8,ACLY,SYT9,EYA1,KCNIP2,KLHL32,LRRTM4,KIAA1109,LRRC7,ANK3,ANXA7,NTNG1,TACC2,MIER1,SLC2A5,SLC8A3,PALLD,MYT1L,KIF1B,SPART,C11orf87,BCL2L2,ALDH1L1,NFIA,DDHD2,TMEM136,KLHL4,MFSD2A,HPS5,PCDH9,MAGI1,SCRG1,CCSER2,OPALIN,MFSD4A,DOCK7,TOX,ZNF385B,PSMD13,PTCH1,BLOC1S6,KCNA4,KCNA6,PTPRE,KCNK1,KCNK2,NAV2,HS3ST4,PLEKHB2,PARP11,SH3GLB1,ELAVL4,BAALC" MicroRNA hsa-miR-3167:mirSVR_highEffct hsa-miR-3167:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.36E-20 3.98E-16 3.14E-19 2.88E-18 60 1134 "SERPINA3,CDHR1,ARID1A,RTN1,WAC,SORCS1,NLGN4X,TOMM40L,TESK2,LINC00461,SEMA6A,FOXM1,ANK1,ANK2,ANK3,APBA2,MAGI3,USP16,SLC2A5,RUFY2,MSRA,SMARCE1,ATP2B2,PALLD,SOX5,EMC1,TTLL9,SPART,ZNF302,ADHFE1,SYT4,GNAS,DDHD2,GPM6A,LRIT2,TCF12,SYT6,GRIA4,TMEM257,PAX6,ZNF384,PDYN,KIAA1549L,NEGR1,DNAJC12,PMP2,MED1,SNCAIP,FEZ1,PRKACB,NRSN1,DNAJC6,MAGI2,OLFM3,PTPRE,KCNN3,SLC25A48,RALGDS,JMJD1C,EPB41" MicroRNA hsa-miR-648:mirSVR_highEffct hsa-miR-648:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.54E-20 4.08E-16 3.21E-19 2.95E-18 41 524 "ADGRV1,ATAT1,CSMD3,GRAMD1B,TOMM40L,FGF1,BCAR3,MOG,ITSN1,NTNG1,SLC14A1,SORCS3,GLS,DDHD2,ANO4,GPM6A,NRGN,PTBP2,GRIA2,GPR88,LINC00839,CDC42,TPD52,PDE3B,CASC2,PRRX1,PPP3CB,NCAN,PKN2,PLD5,USP54,PUM1,TOMM20,COPS7A,RABGAP1L,JMJD1C,TTLL7,ARHGAP12,RAVER2,TMEM100,PRRT4" MicroRNA hsa-miR-320c:mirSVR_highEffct hsa-miR-320c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.57E-20 4.10E-16 3.22E-19 2.96E-18 67 1394 "ADGRV1,EYA1,WLS,WAC,ERMN,SLC44A5,SEMA6A,SELL,AMPH,ITSN1,SESN3,MAGI3,SLITRK3,TACC2,SHTN1,MIER1,CSPG5,ASPH,SORCS3,TMEM108,NRG3,PALLD,SON,WDTC1,CAB39,B4GALNT1,DNER,LMO3,CAMSAP2,KLHL4,CACNA1E,PTBP2,VXN,GRIA4,GPR88,INA,ZFP91,MAEL,PCDH9,TPM3,PCSK2,PDE3B,PRMT8,HMGB1,ARHGAP22,NEGR1,CNTN1,PRRX1,CNRIP1,PPP3CB,PRKCG,IGSF1,PUM1,ANKS1B,PLPPR1,PRTFDC1,CDH20,TMEM255A,SLC17A6,GOPC,GNE,DTNA,PAK5,RFX4,RGS10,SSPN,TMEM100" MicroRNA hsa-miR-24-1*:mirSVR_lowEffct hsa-miR-24-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.92E-20 4.29E-16 3.37E-19 3.09E-18 50 795 "MDM4,SORCS1,BCAR3,CDC42BPA,APC,CCDC80,ARHGAP5,SLC8A3,CCDC88A,SLCO1A2,ASTN1,WDTC1,SOX1,NFASC,DCAF5,NEUROD1,PCDH11X,CAMTA1,UNC5D,MMD2,GPM6A,CACNA1E,PTBP2,CAMK2A,NUMA1,TMEM25,CDH10,IGFN1,PRMT8,PRRX1,SNCAIP,PRKAB2,DZIP3,PKN2,FGFR1OP2,ZBTB16,RGMA,PTPRE,KCNH1,KCNJ10,KCNMA1,DNAH9,SLC17A6,SUSD4,ABI1,ATN1,ZYG11B,RFX4,VWA5A,RCAN2" MicroRNA hsa-miR-326:TargetScan hsa-miR-326 TargetScan 8.71E-20 4.72E-16 3.70E-19 3.39E-18 35 369 "APC2,KCNIP2,FGF1,GOLGA7B,ITSN1,JAKMIP3,SCMH1,GPR153,ATP2B2,CPLX2,NPAS3,BCL2L2,FAM168A,RHBDL3,BTRC,NRGN,GRIN1,KCNK10,PADI2,RBFOX2,CHRM1,DLGAP3,PPP3CB,NCAN,SDC3,KIAA0513,KCNC1,KCND3,KCNH1,DLG3,NKAIN1,BSDC1,EFNA3,ABI2,EPB41L1" MicroRNA hsa-miR-330-5p:TargetScan hsa-miR-330-5p TargetScan 8.71E-20 4.72E-16 3.70E-19 3.39E-18 35 369 "APC2,KCNIP2,FGF1,GOLGA7B,ITSN1,JAKMIP3,SCMH1,GPR153,ATP2B2,CPLX2,NPAS3,BCL2L2,FAM168A,RHBDL3,BTRC,NRGN,GRIN1,KCNK10,PADI2,RBFOX2,CHRM1,DLGAP3,PPP3CB,NCAN,SDC3,KIAA0513,KCNC1,KCND3,KCNH1,DLG3,NKAIN1,BSDC1,EFNA3,ABI2,EPB41L1" MicroRNA hsa-miR-154:mirSVR_highEffct hsa-miR-154:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.74E-20 4.73E-16 3.71E-19 3.40E-18 52 862 "TTYH1,RTN3,MDM4,KLHL32,WAC,GPR158,SCN3A,FGF14,FHL1,SLC30A10,MOBP,ANK3,PKNOX2,SORCS3,TMEM108,EMC1,ARHGEF7,ZNF638,SYT4,KAZN,GNAS,GOLGB1,ANO4,TCF12,PTBP2,CAMK2G,CECR2,SYT6,CRB1,FBXL16,PCSK2,ZBED5,OPALIN,PRRX1,MED1,KCNT2,MASP1,WBP1L,PTHLH,CADM2,RABGAP1L,KCNK2,PCDH15,RAB5B,TMEM255A,ABI1,DTNA,ABCC9,RET,TTLL7,TMEM100,RCAN2" MicroRNA hsa-miR-582-3p:mirSVR_lowEffct hsa-miR-582-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.77E-20 4.75E-16 3.72E-19 3.41E-18 69 1475 "PRR5L,ACHE,LGR4,CSMD3,AMER2,SLC44A5,SFPQ,CDC42BPA,ITSN1,SH3GL2,NTNG1,SFMBT2,RUFY2,CCDC88A,CADPS,SLCO1A2,SPHKAP,ASPH,MEGF11,ZCCHC24,ZSWIM8,DNER,NDUFA5,STOX1,NEUROD1,ZNF638,KAZN,GNAS,CAMTA1,BTRC,GOLGB1,ATF7,ZEB1,AZIN2,OMG,FBXL16,TMEM257,PCDH9,CDH8,LGI1,BEST3,JAM2,NLGN3,KIAA1549L,NRXN1,CRLS1,RGS6,OSBPL3,ATRNL1,DOCK7,BRINP3,TOX,PTCH1,ITGAV,CADM2,STMN4,PTPRE,KCNMA1,OLIG1,DSCAM,ABCC9,RGS10,ZNF248,SYT15,RNF220,RPRD1A,ARHGAP12,ELAVL3,TMEM100" MicroRNA hsa-miR-1207-3p:mirSVR_highEffct hsa-miR-1207-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.83E-20 4.78E-16 3.74E-19 3.43E-18 46 672 "MRVI1,CSMD3,SORCS1,TMEM156,AMER2,SCN3A,PLA2G6,BCAS1,PAAF1,BRINP2,NMNAT2,C11orf87,DCAF5,NELL1,GANAB,ARHGEF7,GNAS,ANO4,FAM69C,DDR1,PRLHR,TCF7L2,AZIN2,GRIA4,INA,P2RX7,PRMT8,TJP2,CELF5,PTPA,SNCAIP,MICAL2,NRSN1,GON4L,CA10,RABGAP1L,KCNMA1,OLIG1,PID1,SLC25A48,PARP11,DBX2,FAM135B,ZNF248,RLBP1,SLC4A10" MicroRNA hsa-miR-100*:mirSVR_highEffct hsa-miR-100*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.10E-20 4.93E-16 3.85E-19 3.53E-18 53 896 "ZFYVE27,RTN3,ACTN2,CSMD3,FGF14,BCAR3,SOX6,PPFIA1,SH3GL2,API5,PDE8B,SPHKAP,MYT1L,B3GALT2,TNIK,SOX5,ENKUR,DNER,NDUFA5,ADHFE1,NEUROD1,KAZN,CACNB2,TCF12,PTBP2,SYT6,GRIA2,GRIA4,OLR1,MFSD2A,PAH,PCDH9,PDE2A,ST8SIA5,PRRX1,PACSIN1,CNRIP1,CRMP1,RNF14,PRKCZ,PTCH1,PTHLH,PRDM2,CEP170,OCIAD1,PTPRD,KCNC1,TMEM255A,RASGRF1,DTNA,RTN4,SH3GLB1,BAALC" MicroRNA hsa-miR-23b*:mirSVR_lowEffct hsa-miR-23b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-19 5.55E-16 4.33E-19 3.98E-18 59 1106 "ZFYVE27,SRARP,MEG3,ATAT1,SLC25A25,TMEM156,TOMM40L,FGF1,LRRC7,FOXM1,CNIH2,ITSN1,ZCCHC17,NLGN1,CCDC88A,ASTN1,SMARCE1,TMEM108,PALLD,WDTC1,CADM3,ENKUR,EMC1,ADGRB2,SPART,COLGALT2,ALDH1L1,GLS,PCDH11X,OS9,TBX15,ZEB1,CLEC9A,PSD3,GRIA1,GRIA2,GRIA4,HPS5,BEST3,CPT1C,A2ML1,BEST1,ATCAY,PNKD,PPP3CB,DOCK7,KIAA1755,PRKCZ,TOX,JAKMIP2,PTPRD,SMG7,PLPPR4,SV2A,KCNJ10,CAB39L,PARP11,L1CAM,EPB41L1" MicroRNA hsa-miR-101:mirSVR_highEffct hsa-miR-101:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.06E-19 5.75E-16 4.49E-19 4.12E-18 66 1365 "ACLY,EYA1,ARID1A,MDM4,ERMN,AMER2,KIAA1109,LRRC7,UNC79,PPFIA1,SHTN1,ARHGAP5,CCDC88A,ASCL1,SORCS3,SON,B3GALT2,ERBIN,DCAF5,NEUROD1,AJAP1,GLS,ZNF638,SYT4,CAMTA1,CAMSAP2,GPM6A,CACNB2,TCF7L2,ZEB1,TCF12,CECR2,GRIK2,TGFBR3,TMEM257,CDC42,PCDH8,CDH8,MAGI1,TMEFF2,CADM1,NRXN1,NEGR1,TJP2,SULT4A1,CNTN1,FAT3,NXPH1,SF1,PPP3CB,PHACTR3,CTNND2,ZNF385B,PTHLH,CADM2,CNIH3,MAGI2,BLOC1S6,ZC3H11A,KCNA1,PLPPR4,NTM,RABGAP1L,SLC17A6,RFX4,JMJD1C" MicroRNA hsa-miR-1258:mirSVR_highEffct hsa-miR-1258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-19 5.80E-16 4.53E-19 4.15E-18 47 706 "TMEM74,MBP,CNTNAP3,ACTN2,SLC25A25,KLHL32,LRRTM4,FGF1,SOX6,ZCCHC17,ST3GAL3,SLC1A6,ASCL1,CAPRIN2,ASPH,SORCS3,WDTC1,AHCYL1,DNER,FXYD6,SPART,VAMP1,GNAS,TCF7L2,TCF12,PTBP2,GRIA2,GRIA4,LEFTY2,TJP1,LGI1,PDYN,ANO5,ATRNL1,VCAN,RBPJ,FMN2,PRDM2,MAGI2,OLFM3,PTPRE,PLPPR4,TMEM255A,PAK5,SLC6A15,ZYG11B,SLC4A10" MicroRNA hsa-miR-510:mirSVR_highEffct hsa-miR-510:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-19 6.14E-16 4.79E-19 4.39E-18 47 707 "EPS8,CSMD2,ADD3,KIAA1109,LRRC7,SLC30A10,MAGI3,GPAM,BCAS1,CADPS,SORCS3,RCOR3,DKK3,NPAS3,ADHFE1,FAM168A,GNAS,ANO4,GPM6A,PRLHR,NUDT21,GRIA4,LGI1,MAGI1,PDE1C,PLEKHB1,CASC2,CADM1,CCDC136,VAV2,MEAF6,CHD1L,SF1,TOX,GON4L,TUBB2B,LRRTM3,PTAFR,MAGI2,STMN4,ZC3H11A,PTPRZ1,RABGAP1L,RET,PHC2,SEC61A2,RCAN2" MicroRNA hsa-miR-4303:mirSVR_highEffct hsa-miR-4303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-19 6.43E-16 5.01E-19 4.59E-18 48 739 "ACTN2,EYA1,LDLRAD3,SORCS1,LRRC7,FGR,ANK2,APC,SORBS1,ASPH,ATM,GABBR1,SOX5,ZSWIM8,ARPP21,KIF1B,NPAS3,NCAM1,ALDH1L1,ADHFE1,RHBDL3,PCDH11X,LUZP2,DDHD2,PRUNE2,PTBP2,GRIA1,GRIA4,GRID1,TF,INA,TMEM257,CDC42,JAM2,ZFYVE9,CNTN1,BTBD17,RNF14,NKAIN4,MICAL2,PLD5,LRP8,COPS7A,KCNK1,KCNK2,SLC25A48,RAD52,SSPN" MicroRNA hsa-miR-508-3p:mirSVR_highEffct hsa-miR-508-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-19 6.60E-16 5.13E-19 4.71E-18 53 902 "RTN3,ATAT1,F3,CLIP1,SORCS1,FCGR1A,MOBP,ERICH3,ANXA7,CAPRIN2,SORCS3,ASTN1,PHYHIPL,PALLD,IDI2-AS1,LMO3,C11orf87,UNC5D,ADGRL3,CACNB2,ZEB1,CECR2,GRIA2,GRIA4,GRIK2,OLR1,CRB1,MAEL,TPM3,PMS2,KCNT2,ATRNL1,PUM1,ECE2,MASP1,BRINP3,JAKMIP2,HP1BP3,MAGI2,PTPRD,KCNA6,AK5,KCNK1,TMEM255A,RAD52,C12orf4,RASGRF1,DBX2,RPRD1A,CBLN2,RAVER2,RPE65,UEVLD" MicroRNA hsa-miR-320d:mirSVR_highEffct hsa-miR-320d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-19 6.68E-16 5.19E-19 4.77E-18 66 1369 "ADGRV1,EYA1,WLS,WAC,ERMN,SLC44A5,SEMA6A,SELL,AMPH,ITSN1,SESN3,MAGI3,SLITRK3,TACC2,SHTN1,MIER1,CSPG5,ASPH,SORCS3,TMEM108,NRG3,PALLD,SON,WDTC1,CAB39,B4GALNT1,DNER,LMO3,CAMSAP2,CACNA1E,PTBP2,VXN,GRIA4,GPR88,INA,ZFP91,MAEL,PCDH9,TPM3,PCSK2,PDE3B,PRMT8,HMGB1,ARHGAP22,NEGR1,CNTN1,PRRX1,CNRIP1,PPP3CB,PRKCG,IGSF1,PUM1,ANKS1B,PLPPR1,PRTFDC1,CDH20,TMEM255A,SLC17A6,GOPC,GNE,DTNA,PAK5,RFX4,RGS10,SSPN,TMEM100" MicroRNA hsa-miR-212-5p:TargetScan hsa-miR-212-5p TargetScan 1.34E-19 7.26E-16 5.64E-19 5.17E-18 33 326 "RIMKLA,MRVI1,AMER2,DRAXIN,PKP4,KIAA1614,LRRC55,C10orf105,GABBR1,RAP1GAP2,CLASP2,BCL2L2,ALDH1L1,NFIA,CNTN2,GPM6B,CACNA1E,DDR1,GRIK3,GRIN1,MFSD2A,PIRT,FNDC5,FTO,PRRX1,RBPJ,PROX1,LRRTM3,DLG3,CALN1,RALGDS,PIANP,CBLN2" MicroRNA hsa-miR-4274:mirSVR_lowEffct hsa-miR-4274:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-19 7.67E-16 5.96E-19 5.47E-18 67 1411 "SYT9,ADGRV1,CSMD3,NDRG2,FOXRED2,KIAA1109,BCAR3,FHL1,ANK3,SH3GL2,APBB1,APC,SHTN1,CLSTN1,MIER1,RPH3A,ARHGAP5,NSG2,CAPRIN2,SMARCE1,ATM,NRG3,EIF4G3,USP33,SOX5,GART,C11orf87,ARHGEF7,PCDH11X,CAMTA1,BTRC,WWC1,PTBP2,CAMK2G,GPR88,CYB561A3,TJP1,PAH,TNFRSF1B,TPD52,ZNF384,LINC01102,ZMYND8,BEST3,HMGB1,COL9A2,P2RY12,FAT3,PPP3CB,PRKACB,PROX1,MASP1,ZNF385B,BDNF-AS,CSDE1,PTPRD,SMG7,RABGAP1L,CCDC3,PID1,DTNA,RTN4,PAK5,RET,ATL1,CBLN2,SLC4A10" MicroRNA hsa-miR-224:mirSVR_highEffct hsa-miR-224:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.50E-19 8.12E-16 6.29E-19 5.77E-18 60 1151 "ACLY,RBM10,SYT9,ATAT1,ADAR,KLHL32,SLC44A5,GPR158,FGF14,ITSN1,APBA2,ZCCHC17,API5,ZNF365,RUFY2,MSRA,SCG3,DNAH17,ASPH,MYT1L,ARPP21,TTLL9,CLASP2,NELL1,AJAP1,GLS,ZNF638,GPM6A,TCF12,EML4,VSTM2A,GRIA4,GRIK4,TMEM257,CDC42,CIART,LINC01102,BEST3,PFKFB3,MEAF6,POU3F2,CHD1L,RBPJ,MASP1,WBP1L,SYTL2,GON4L,HP1BP3,COPS7A,KCNMA1,SLC17A6,DTNA,RTN4,SLC6A15,RFX4,FAM135B,ZNF248,EFNA3,SLC4A10,EPB41L2" MicroRNA hsa-miR-1179:mirSVR_highEffct hsa-miR-1179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-19 8.13E-16 6.29E-19 5.77E-18 59 1115 "RBM10,SYNDIG1,ADD3,CDC7,ERMN,TOMM40L,SCN3A,SCN4B,KIAA1109,LRRC7,CNIH2,ITSN1,NTNG1,ARHGAP5,ASCL1,SCG3,SPHKAP,RCOR3,SNAP25,MYT1L,CAB39,NCAM1,CLASP2,STOX1,OS9,CAMTA1,PRUNE2,GPM6A,ZEB1,LINC00839,PCDH9,SEZ6L,LGI1,TPM4,MAGI1,PDYN,HMGB1,SPATA6,SNCAIP,KCNT2,VCAN,DZIP3,PKN2,GON4L,SPIRE1,PTCH1,PTHLH,BLOC1S6,KCNA4,PLPPR4,PTPRO,C1orf109,RABGAP1L,KCNK2,PID1,BSDC1,SYT15,VWA5A,CBLN2" MicroRNA hsa-let-7g-5p:TargetScan hsa-let-7g-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7f-5p:TargetScan hsa-let-7f-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7a-5p:TargetScan hsa-let-7a-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7c-5p:TargetScan hsa-let-7c-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7e-5p:TargetScan hsa-let-7e-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-miR-98-5p:TargetScan hsa-miR-98-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7b-5p:TargetScan hsa-let-7b-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7i-5p:TargetScan hsa-let-7i-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-let-7d-5p:TargetScan hsa-let-7d-5p TargetScan 1.51E-19 8.17E-16 6.29E-19 5.77E-18 52 873 "ACER3,RIMKLA,APC2,LGR4,RCSD1,MDM4,GRAMD1B,SCN4B,ITSN1,GAS7,B3GAT1,MEGF11,DKK3,KIF21B,SALL3,ADAM15,CLASP2,ARHGEF7,ACSL6,CACNA1E,GPR26,CECR2,GRIK2,ADAMTS8,OLR1,AIFM1,RBFOX2,BTF3L4,PRRX1,OSBPL3,RBPJ,PRKAB2,PKN2,PLD5,IGSF1,MAPK8,RIMS3,PTAFR,CADM2,RGMA,BLOC1S6,PTPRD,KCNA6,KCNC1,KCNJ11,KIF2A,CALN1,ATG16L1,GOPC,GPR61,RAVER2,PLEKHO1" MicroRNA hsa-miR-206:mirSVR_highEffct hsa-miR-206:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.54E-19 8.32E-16 6.40E-19 5.87E-18 61 1188 "RABEPK,ACER3,ADGRV1,ADAR,CHST15,ASRGL1,ITSN1,API5,ZNF365,MIER1,DACH2,CGREF1,SCG3,ASPH,SORCS3,TMEM108,SNAP25,USP33,SOX5,ILDR2,GAD2,NPAS3,FGF17,NEUROD1,ACSBG1,GLS,WWC1,ANO4,GPR17,MAEL,CDC42,SEZ6L,LGI1,TPM3,MAGI1,PIRT,HNRNPK,GDAP1L1,MED1,RNF14,PRKACB,DZIP3,PLPPR1,JAKMIP2,ELMO1,HP1BP3,OCIAD1,SMG7,PLPPR4,KCNK2,KIF2A,SLC17A6,PARP11,SLC6A15,CRTAC1,RGS7,SYT15,RNF220,SLC4A10,BSCL2,EN2" MicroRNA hsa-miR-2110:mirSVR_highEffct hsa-miR-2110:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-19 8.48E-16 6.52E-19 5.98E-18 59 1116 "ASIC1,CNTNAP3,LGR4,GRAMD1B,ADORA3,FGF14,BCAR3,TRIM46,SFPQ,ITSN1,RPH3A,SCG3,SLN,DKK3,GABBR1,MYT1L,ARPP21,TTLL9,SPART,NCDN,ADHFE1,GLS,POPDC3,LUZP2,CNDP1,PTBP2,VXN,NUMA1,CRB1,USP2,CDC42,PADI2,BEST3,HMGB1,CASC2,TJP2,RNF14,SNCAIP,KCNT2,PRKACB,RAB39A,PRKCG,IGSF1,MASP1,ANKS1B,CNIH3,CEP170,KCND3,SV2A,PCDH15,KCNMA1,PYGM,OLIG1,RFX5,PHC2,SLC4A10,YY1AP1,PRRT4,EPB41L1" MicroRNA "GTGCCAA,MIR-96:MSigDB" "GTGCCAA,MIR-96:MSigDB" MSigDB 1.71E-19 9.24E-16 7.09E-19 6.51E-18 31 283 "ABAT,SLC25A25,SEMA6A,SOX6,TRIM46,ST3GAL3,SLC1A2,SLC6A9,BRINP2,FYN,SOX5,B4GALNT1,RAP1GAP2,CAMTA1,CDK5R2,TBX15,GPM6A,GPM6B,GRID1,MAGI1,NRXN1,CABP1,PRRX1,RIMS4,CTNND1,PMEPA1,CEP170,PLPPR4,ATG16L1,BSDC1,JMJD1C" MicroRNA hsa-miR-514b-3p:mirSVR_highEffct hsa-miR-514b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-19 9.42E-16 7.23E-19 6.64E-18 48 746 "EPS8,RTN1,FABP7,ERMN,SCN3A,LRRTM4,TRIM46,SESN3,NTNG1,ZNF365,ARFGAP2,DACH2,NAXD,PHYHIPL,SON,GAD2,B4GALNT1,NPAS3,ERBIN,DCLK2,TCF12,GRIA2,GRIK2,PDE3B,ANO5,CADM1,CELF5,BTF3L4,SPATA6,FAAP20,ETNPPL,USP54,PLPPR5,SYNC,LRRTM3,BDNF-AS,PTHLH,MAGI2,OLFM3,PLPPR4,PTPRZ1,RABGAP1L,KCNK2,ABI1,GNE,ABCC9,ELAVL4,BAALC" MicroRNA hsa-miR-138-1*:mirSVR_highEffct hsa-miR-138-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-19 9.51E-16 7.29E-19 6.69E-18 49 778 "MDM4,CDC7,LRRC7,SFPQ,FOLH1,NTNG1,SLITRK3,BCAS1,SHTN1,ZNF365,CAPRIN2,CCDC181,PHYHIPL,USP33,DCAF5,ADHFE1,NEUROD1,GLS,CASTOR3,ZNF638,CAMSAP2,KLHL4,ANO4,PTBP2,GRIA4,INA,AIFM1,ZNF384,GDAP1L1,NMT2,SLC25A27,CHD1L,SNCAIP,KCNT2,OSBPL3,ATRNL1,NCAN,PRKACB,DZIP3,BDNF-AS,CEP170,SMG7,DNAH9,DPP6,C12orf4,ABI1,PAK5,JMJD1C,SFXN5" MicroRNA "TTGCCAA,MIR-182:MSigDB" "TTGCCAA,MIR-182:MSigDB" MSigDB 1.80E-19 9.76E-16 7.48E-19 6.86E-18 32 306 "ATAT1,ADCY2,ADD3,PDZD4,ANK2,ANK3,PPM1E,NTNG1,SLC1A2,PALLD,GABBR1,NFASC,ARHGEF7,NKX2-2,CAMTA1,CAMSAP2,PC,PCDH8,MAGI1,VAV2,PRRX1,NSD2,PRKACB,RIMS3,PTHLH,ELMO1,PLPPR4,RALGDS,DSCAM,RTN4,L1CAM,RET" MicroRNA hsa-miR-1290:PITA hsa-miR-1290:PITA_TOP PITA 1.81E-19 9.78E-16 7.49E-19 6.87E-18 34 353 "DSCAML1,GALNT13,SORCS1,NLGN4X,SEMA6A,UNC79,AMPH,ARHGAP5,CCDC88A,NKX2-2,CAMTA1,UNC5D,MAGI1,PDE3B,NLGN3,CADM1,NRXN1,PACSIN1,POU3F2,MED1,CTNND1,FAM131B,WBP1L,LRRTM3,CADM2,SMG7,KCNK2,DLG3,TMEM255A,RALGDS,ABI2,ELAVL3,EN2,RCAN2" MicroRNA hsa-miR-4317:mirSVR_lowEffct hsa-miR-4317:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-19 9.78E-16 7.49E-19 6.87E-18 61 1192 "DPF1,RABEPK,ACER3,CSMD3,ADCY2,SORCS1,DRAXIN,MOBP,RASA3,ITSN1,ANXA7,PKP4,DOCK10,SESN3,SLITRK3,ST3GAL3,RPH3A,SHANK2,LGI3,ASPH,SMARCE1,KBTBD12,ALDH4A1,SON,SOX5,ENKUR,NFASC,NCAM1,PHLDB1,GANAB,SEPT3,ZNF638,KAZN,DDHD2,GOLGB1,TBX15,NRDC,EML4,GRIK2,GRM3,ZDHHC22,ZFP91,DAAM2,REPS2,CDC42,MAGI1,PDE4B,CHRM1,ANLN,PLXNB3,POU3F2,RGS6,RBPJ,CA10,JAKMIP2,MAGI2,OCIAD1,PLPPR4,KCNJ10,DLG3,PIANP" MicroRNA hsa-miR-708:mirSVR_highEffct hsa-miR-708:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.84E-19 9.95E-16 7.61E-19 6.98E-18 48 747 "SDE2,ACHE,FABP7,SLC44A5,SCN3A,FGF1,AMPH,PPFIA1,ITSN1,PKP4,PKNOX2,SHANK2,SMARCE1,SNAP25,GAD2,FXYD6,NELL1,RGL1,ADHFE1,SLCO1C1,GNG4,GPM6A,PTBP2,NUMA1,OLR1,CRB1,GUCY1A2,TIE1,TMEM9,MAEL,SERPINE2,TJP2,ETNPPL,SNCAIP,OSBPL3,NCAN,PRKCZ,GON4L,PRDM2,MED24,SMG7,C1orf109,NTM,PCDH15,JMJD1C,RPRD1A,YY1AP1,EN2" MicroRNA hsa-miR-320a:mirSVR_highEffct hsa-miR-320a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-19 1.10E-15 8.43E-19 7.73E-18 67 1421 "ADGRV1,EYA1,WLS,WAC,ERMN,SLC44A5,SEMA6A,SELL,AMPH,ITSN1,SESN3,MAGI3,SLITRK3,TACC2,SHTN1,MIER1,CSPG5,ASPH,SORCS3,TMEM108,NRG3,PALLD,SON,WDTC1,CAB39,B4GALNT1,DNER,LMO3,ARHGEF7,CAMSAP2,KLHL4,CACNA1E,PTBP2,VXN,GRIA4,GPR88,INA,ZFP91,MAEL,PCDH9,TPM3,PCSK2,PDE3B,PRMT8,HMGB1,ARHGAP22,CNTN1,PRRX1,PPP3CB,PRKCG,IGSF1,PUM1,ANKS1B,PLPPR1,PRTFDC1,CDH20,TMEM255A,SLC17A6,FAM66C,GOPC,GNE,DTNA,PAK5,RFX4,RGS10,SSPN,TMEM100" MicroRNA hsa-miR-320b:mirSVR_highEffct hsa-miR-320b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-19 1.10E-15 8.43E-19 7.73E-18 67 1421 "ADGRV1,EYA1,WLS,WAC,ERMN,SLC44A5,SEMA6A,SELL,AMPH,ITSN1,SESN3,MAGI3,SLITRK3,TACC2,SHTN1,MIER1,CSPG5,ASPH,SORCS3,TMEM108,NRG3,PALLD,SON,WDTC1,CAB39,B4GALNT1,DNER,LMO3,ARHGEF7,CAMSAP2,KLHL4,CACNA1E,PTBP2,VXN,GRIA4,GPR88,INA,ZFP91,MAEL,PCDH9,TPM3,PCSK2,PDE3B,PRMT8,HMGB1,ARHGAP22,CNTN1,PRRX1,PPP3CB,PRKCG,IGSF1,PUM1,ANKS1B,PLPPR1,PRTFDC1,CDH20,TMEM255A,SLC17A6,FAM66C,GOPC,GNE,DTNA,PAK5,RFX4,RGS10,SSPN,TMEM100" MicroRNA hsa-miR-575:mirSVR_highEffct hsa-miR-575:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.11E-19 1.14E-15 8.69E-19 7.98E-18 46 687 "ZFYVE27,RBM10,SYT9,RCSD1,CSMD3,FABP7,SLC44A5,TOMM40L,LRRTM4,MOG,ANK3,PKP4,AQP4,MADD,DACH2,GABBR1,TNIK,ZSWIM8,ARPP21,TTLL9,STOX1,ROBO3,ANO4,PTBP2,EML4,GRIA2,MFSD2A,DCLK1,MAGI1,PDE1C,PRMT8,CELF5,BTF3L4,NXPH1,RNF14,PTPA,TOX,SYNC,BDNF-AS,CADM2,PARP11,FAM13C,DBX2,RFX5,FAM135B,EN2" MicroRNA hsa-miR-4309:mirSVR_highEffct hsa-miR-4309:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.19E-19 1.19E-15 9.04E-19 8.29E-18 44 627 "DUSP27,ATAT1,WAC,FABP7,ERMN,TUBB4A,ELMOD1,PKP4,APC,NTNG1,CACHD1,ST3GAL3,RUFY2,MT3,DACH2,ASCL1,ASPH,SNAP25,SOX1,B3GALT2,ILDR2,ROBO3,CAMTA1,TBX15,GRIA2,GRIA4,CRB1,LGI1,PCSK2,HMGB1,JAM2,P2RY12,SNCAIP,RGS6,VCAN,PLPP4,USP54,DNAJC6,WIPF2,DNM2,SUSD4,DTNA,RFX4,RGS7" MicroRNA hsa-miR-185-5p:TargetScan hsa-miR-185-5p TargetScan 2.30E-19 1.24E-15 9.48E-19 8.70E-18 30 264 "ASIC1,CSMD2,MDM4,DNAH17,ATP1A3,NMNAT2,KIF1B,BCL2L2,PHLDB1,FAM168A,CNTN2,GPR26,CDC42,PADI2,FNDC5,GPR37L1,DLGAP3,CADM1,RIMS4,NRSN1,PHYHIP,CA10,HP1BP3,KCND3,KCNN3,DLG2,CALN1,CAMK1G,GPR61,ELAVL3" MicroRNA hsa-miR-569:mirSVR_highEffct hsa-miR-569:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-19 1.26E-15 9.60E-19 8.80E-18 55 984 "LGR4,CSMD3,CLIP1,SEMA6A,MAGI3,AQP4,ZNF365,SPHKAP,SMARCE1,SOX5,GART,NPAS3,MMD2,BTRC,PRUNE2,CACNB2,TCF7L2,GRIA2,GRIA4,GPR88,CDC42,LGI1,CASC2,A2ML1,CNTN1,SPATA6,SLC36A4,MFSD4A,CP,CRLS1,FEZ2,FMN2,RAB39A,PKN2,USP54,LRRTM3,ITGAV,KCNA4,OCIAD1,PTPRD,PTPRZ1,KCNK1,SNX27,DLG2,TMEM255A,PLEKHB2,FAM13C,ABCC9,SYT15,SEC61A2,SLC39A12,SH3GLB1,FGFBP3,LPAR6,ELAVL4" MicroRNA hsa-miR-17*:mirSVR_highEffct hsa-miR-17*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-19 1.27E-15 9.67E-19 8.87E-18 56 1019 "SERPINA3,ACLY,CNTNAP3,MDM4,CSMD3,SLITRK1,SLC30A10,SOX6,ANK2,ANK3,ITSN1,NLGN1,BCAS1,API5,RUFY2,ASTN1,USP33,JPH4,ARPP21,SALL3,DNER,CLASP2,RGL1,ZNF638,GNAS,CACNB2,ZEB1,TCF12,NRDC,AKNA,GRM3,INA,HPS5,LINC01102,TMEFF2,MEAF6,SF1,FEZ2,RAB39A,KLK6,TOX,KIAA0513,ANKS1B,SYNC,PTHLH,BLOC1S6,KCNC1,PTPRO,PTPRZ1,KCNMA1,PHC2,TTLL7,FGFBP3,SLC4A10,RPE65,UEVLD" MicroRNA hsa-miR-606:mirSVR_highEffct hsa-miR-606:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-19 1.29E-15 9.80E-19 8.99E-18 59 1126 "EPS8,SDE2,RCSD1,EYA1,IL17D,ARID1A,ERMN,SLC44A5,FHL1,SFPQ,SGIP1,APC,NLGN1,API5,SHTN1,RUFY2,MSR1,CCDC88A,SCG3,ASPH,SMARCE1,SNAP25,NRG3,ENKUR,TTLL9,NDUFA5,DCAF5,PCDH11X,KAZN,CAMTA1,TCF7L2,NRGN,VXN,TMEM257,PAH,PAX6,PCDH8,ANO5,ANLN,MEAF6,PPP2R5C,RBPJ,PLD5,USP54,CTNND2,PLPPR5,PSMD13,CEP170,OCIAD1,PTPRZ1,PCDH15,SLC17A6,FAM13C,SLC6A15,SLC39A12,SSPN,RPRD1A,EPB41,EPB41L2" MicroRNA "TTTGTAG,MIR-520D:MSigDB" "TTTGTAG,MIR-520D:MSigDB" MSigDB 2.66E-19 1.44E-15 1.09E-18 1.00E-17 32 310 "SORCS1,SCN3A,UNC79,PPM1E,SLITRK3,MIER1,SNAP25,USP33,SON,SOX1,SALL3,NCAM1,SMOC1,GPM6A,GPM6B,TCF7L2,GRM3,DCLK1,FMN2,PUM1,HES5,BRINP3,TOX,ZNF385B,DNAJC6,PRDM2,PTPRZ1,KCNK1,KCNMA1,BSDC1,RFX4,JMJD1C" MicroRNA hsa-miR-562:mirSVR_highEffct hsa-miR-562:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.82E-19 1.53E-15 1.16E-18 1.06E-17 49 787 "MAG,ADD3,WAC,GPR158,PPFIA1,SH3GL2,PPM1E,RUFY2,SLC14A1,ASPH,ATM,SOX5,KIF21B,SPART,CLASP2,SEPT3,ARHGEF7,VAMP1,GOLGB1,GRIA4,MAEL,C1orf94,PCSK2,BEST3,JAM2,CADM1,NRXN1,OPALIN,PMS2,PRRX1,BTBD17,RNF14,PPP2R5C,FEZ2,RBPJ,PLPP4,PROX1,SYNC,MAGI2,PTPRD,PLPPR4,PCDH15,SLC17A6,FAM13C,ABCC9,FGFBP3,C2orf80,UEVLD,BAALC" MicroRNA hsa-miR-1470:mirSVR_lowEffct hsa-miR-1470:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-19 1.58E-15 1.20E-18 1.10E-17 38 461 "MAG,CSMD2,PLEKHG5,ADORA1,SEMA6C,SLC1A6,CGREF1,ARFGAP1,SMARCE1,RCOR3,ATM,NRG3,SON,ZSWIM8,ARPP21,GANAB,VAMP1,CDK5R2,MMD2,ADGRL3,BRSK2,TNR,MAGI1,PDE2A,PRMT8,SERPINE2,SULT4A1,VAV2,MICAL2,NRSN1,WBP1L,PRTFDC1,SMG7,SRGAP3,DNM2,RALGDS,EPB41,UEVLD" MicroRNA hsa-miR-554:mirSVR_lowEffct hsa-miR-554:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.99E-19 1.62E-15 1.23E-18 1.12E-17 52 887 "MAG,SERPINA3,SYT9,RTKN,CSMD3,KLHL32,GRAMD1B,FCGR1A,CNIH2,PPFIA1,ST3GAL3,KIAA1614,SON,TNIK,KIF21B,ARPP21,FXYD6,STOX1,KIRREL3,BTRC,CAMK2A,TMEM9,TLL2,C1orf94,ARHGAP19,PDE2A,TMEFF2,JAM2,GDAP1L1,KIAA1549L,A2ML1,TJP2,FLRT1,ACBD5,PPP2R5C,PPP3CB,USP54,NOS1AP,JAKMIP2,PTHLH,PRDM2,SV2A,KCNMA1,PEX5,KIF2A,FAM66C,RASGRF1,ABCC9,RFX5,SLC39A12,EFNA3,SLC4A10" MicroRNA hsa-miR-3074:mirSVR_highEffct hsa-miR-3074:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-19 1.73E-15 1.31E-18 1.20E-17 58 1097 "ACHE,TMEM74,CNTNAP3,ADGRV1,MDM4,ADD3,ADORA1,LINC00461,ELMOD1,PPM1E,GPAM,CACHD1,PKNOX2,ASPH,ATM,MEGF11,SON,KIF1B,NAP1L2,LMO3,CLASP2,ARHGEF7,SEMA4A,PRUNE2,GPM6A,ACSL6,EML4,GRIA2,GRIA4,CELF3,TNS1,MAGI1,ANO5,NRXN1,ANLN,PMP2,MEAF6,SLC25A27,FEZ2,PRKACB,CTNND2,PTCH1,ITGAV,KCNA2,OCIAD1,PTPRE,NTM,KCNJ10,PCDH15,NAV2,DLG2,DBX2,SLC6A15,JMJD1C,TTLL7,SEC61A2,RNF220,ROM1" MicroRNA hsa-miR-641:PITA hsa-miR-641:PITA_TOP PITA 3.34E-19 1.81E-15 1.37E-18 1.25E-17 39 490 "CLIP1,HPCAL4,SOX6,ANK1,PKP4,MAGI3,GPAM,SLC8A2,RCOR3,PALLD,MYT1L,NPAS3,ERBIN,RGL1,CAMTA1,BTRC,PTBP2,OMG,INA,PCDH9,TPM3,PCSK2,PDE3B,PDE4B,NMT2,CCSER2,MED1,PPP3CB,OSBPL3,PKN2,MAPK10,TOX,SYNC,ZC3H11A,KCNA1,OLFM3,KCNA4,RAB5B,FAM135B" MicroRNA hsa-miR-1270:mirSVR_highEffct hsa-miR-1270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.44E-19 1.86E-15 1.41E-18 1.29E-17 57 1063 "ACTN2,MEG3,CSMD3,ADCY2,FCGR1A,SCN3A,LRRTM4,BBOX1,FOXM1,ERICH3,NTNG1,GPAM,MIER1,MSR1,SPHKAP,KBTBD12,GABBR1,SON,B3GALT2,TTLL9,DNER,LMO3,CLASP2,PCDH11X,ZNF638,DCLK2,NODAL,UNC5D,MMD2,TMEM136,CNDP1,TBX15,PTBP2,GRIA4,TJP1,LGI1,MAGI1,ACOT7,ANO5,CASC2,NECAB2,NXPH1,CHD1L,VCAN,NRSN1,CA10,BDNF-AS,PRDM2,KCNA4,HS3ST4,GOPC,DBX2,DTNA,SLC6A15,ZYG11B,RFX4,RGS7" MicroRNA hsa-miR-1251:mirSVR_lowEffct hsa-miR-1251:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-19 1.96E-15 1.48E-18 1.36E-17 58 1100 "MAP6,MDM4,ADCY2,GALNT13,SORCS1,CHST15,UNC79,SOX6,PKP4,SLITRK3,ZCCHC17,SORBS1,AQP4,ASPH,TMEM108,ATP1A2,TNIK,ARPP21,NFASC,CLASP2,GJB1,GLS,UNC5D,PTBP2,NUDT21,CECR2,TMEM151B,GRIA1,GRIA2,GRIA4,GRM3,CRB1,TJP1,CELF3,LGI1,A2ML1,CCSER2,CABP1,CP,SNCAIP,FEZ2,FMN2,CTNND1,NOS1AP,TOX,GON4L,PLPPR5,BDNF-AS,PRDM2,PTPRZ1,AK5,CAB39L,RALGDS,RTN4,RFX4,VANGL2,SEC61A2,SSPN" MicroRNA hsa-miR-938:mirSVR_lowEffct hsa-miR-938:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-19 2.01E-15 1.52E-18 1.39E-17 50 825 "LOC100128239,SYT9,RTN3,DUSP27,IL17D,ATAT1,FGF14,ERICH3,ANK3,NLGN1,AQP4,NRG3,SCN3B,WDTC1,AHCYL1,JPH4,NEK6,BCL2L2,ALDH1L1,ZNF638,UNC5D,TMEM136,KLHL4,PRUNE2,NUDT21,RFFL,GRIK4,FBXL16,TMEM257,TNR,LGI1,PRMT8,FNDC5,VAV2,PPP3CB,OSBPL3,RIMS4,SPIRE1,PMEPA1,OCIAD1,SMG7,C1orf109,KCNK1,KIF2A,RAB5B,FAM13C,CAMK1G,SSPN,FGFBP3,SLC4A10" MicroRNA hsa-miR-4299:mirSVR_highEffct hsa-miR-4299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.85E-19 2.08E-15 1.57E-18 1.44E-17 47 729 "WLS,CLIP1,LRRC7,FGF14,FOLH1,ITSN1,PKP4,NLGN1,MIER1,SFMBT2,MSR1,SLC8A3,SCG3,PHYHIPL,B3GALT2,NDUFA5,KIRREL3,ZNF638,UNC5D,ADGRL3,ANO4,GPR19,SPX,LEFTY2,INA,TPD52,MAGI1,HPSE2,HERC2P3,HNRNPK,CAMKV,FTO,CCDC136,MFSD4A,SNCAIP,ATRNL1,PLCH2,PLPP4,PTHLH,KCNK1,NKAIN1,ZYG11B,RGS10,RERGL,PRRT4,EPB41,RCAN2" MicroRNA hsa-miR-877:mirSVR_highEffct hsa-miR-877:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.91E-19 2.12E-15 1.60E-18 1.46E-17 50 826 "ADARB2,ADCY2,ERMN,ADORA3,SCN3A,FGF14,FGR,FOXM1,AMPH,ANK2,PKP4,MAGI3,BCAS1,ZNF365,SLC8A3,SLC14A1,AHCYL1,NMNAT2,C11orf87,NDUFA5,DCAF5,ROBO3,CAMTA1,ADGRL3,LILRA1,GRIA2,TLL2,NEURL1,DAAM2,ZMYND8,HMGB1,PLEKHB1,GDAP1L1,KIAA1549L,TJP2,MED1,PPP3CB,IGSF1,BRINP3,PTCH1,OLFM3,C1orf109,SV2A,TMCC2,RFX4,RGS7,VWA5A,OLIG2,RPE65,EPB41L2" MicroRNA hsa-miR-222*:mirSVR_highEffct hsa-miR-222*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-19 2.16E-15 1.63E-18 1.49E-17 52 893 "MEG3,ADGRV1,SLC44A5,TESK2,LINC00461,BCAR3,UNC79,MOBP,CNIH2,PKP4,SLITRK3,API5,MIER1,MSR1,SLC8A3,CCDC88A,SORCS3,SNAP25,PHYHIPL,MEGF11,EMC1,NCAM1,LMO3,NDUFA5,PCDH11X,ZNF638,SYT4,TGFBR3,DCLK1,MS4A7,SERPINE2,MFSD4A,RNF14,OSBPL3,ATRNL1,FMN2,FGFR1OP2,LRRTM3,BDNF-AS,BLOC1S6,SMG7,PTPRE,PTPRZ1,DLG2,KIF2A,ABI1,ATN1,RASGRF1,FAM13C,PAK5,L1CAM,RFX4" MicroRNA hsa-miR-525-5p:mirSVR_highEffct hsa-miR-525-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.00E-19 2.17E-15 1.63E-18 1.49E-17 55 996 "ACER3,RTN1,TUBB4A,MOBP,MOG,SOX6,ASRGL1,PAAF1,CAPRIN2,ASPH,SON,ILDR2,KIF1B,HEPN1,ACSBG1,PCDH11X,NODAL,MMD2,KLHL4,GPM6B,GRIA2,GRIA4,OLR1,CRB1,ZNF384,PDE3B,HERC2P3,JAM2,OPALIN,SULT4A1,BTF3L4,NXPH1,CHD1L,ATRNL1,FMN2,RAB39A,USP54,ARHGEF4,NRSN1,TOX,PSMD13,SIRPA,CADM2,TMCC2,KCNK2,PCDH15,KIF2A,DPP6,RALGDS,SUSD4,PAK5,ABCC9,ZYG11B,EPB41L1,EPB41L2" MicroRNA "AAGCCAT,MIR-135A:MSigDB" "AAGCCAT,MIR-135A:MSigDB" MSigDB 4.29E-19 2.32E-15 1.75E-18 1.60E-17 32 315 "DPF1,WAC,ANK3,ANXA7,GAS7,API5,PDE8B,ATP2B2,SON,MYT1L,B4GALNT1,CPLX2,RGL1,ARHGEF7,ANO4,GPM6B,CACNA1E,FBXL16,TMEM9,NEURL1,HPS5,FNDC5,NEGR1,PPP2R5C,ARHGEF4,ZNF385B,STMN4,SRGAP3,KCNMA1,DLG2,CALN1,PAK5" MicroRNA "AAGCCAT,MIR-135B:MSigDB" "AAGCCAT,MIR-135B:MSigDB" MSigDB 4.29E-19 2.32E-15 1.75E-18 1.60E-17 32 315 "DPF1,WAC,ANK3,ANXA7,GAS7,API5,PDE8B,ATP2B2,SON,MYT1L,B4GALNT1,CPLX2,RGL1,ARHGEF7,ANO4,GPM6B,CACNA1E,FBXL16,TMEM9,NEURL1,HPS5,FNDC5,NEGR1,PPP2R5C,ARHGEF4,ZNF385B,STMN4,SRGAP3,KCNMA1,DLG2,CALN1,PAK5" MicroRNA hsa-miR-587:PITA hsa-miR-587:PITA_TOP PITA 4.88E-19 2.64E-15 1.99E-18 1.82E-17 36 415 "ASIC1,ACLY,SYNDIG1,SLITRK1,GALNT13,SNX30,PKP4,GPAM,API5,CADPS,SORCS3,MYT1L,NMNAT2,ERBIN,GFAP,RGL1,NKX2-2,CAMTA1,EML4,GRIA2,GRM3,PCDH9,CDH10,HNRNPK,CADM1,MEAF6,NSD2,NXPH1,MED1,CHD5,CTNND2,TOX,MAGI2,ZC3H11A,SMG7,ABI2" MicroRNA hsa-miR-515-5p:PITA hsa-miR-515-5p:PITA_TOP PITA 5.18E-19 2.81E-15 2.11E-18 1.93E-17 32 317 "GPR158,DGKD,SLITRK3,ST3GAL3,API5,SHTN1,PKNOX2,ASCL1,SMARCE1,SNAP25,MEGF11,CAB39,NMNAT2,BCL2L2,CACNA1A,TCF12,GRIA4,MAEL,MED1,PUM1,HP1BP3,CEP170,KCNA4,PTPRD,PTPRE,DLG2,KIF2A,EFNA3,RBM12,GPR61,ABI2,RASGRP2" MicroRNA hsa-miR-1255b:mirSVR_highEffct hsa-miR-1255b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.19E-19 2.81E-15 2.11E-18 1.93E-17 45 672 "RTN3,WLS,KLHL32,SCN3A,PLA2G6,MOG,SGIP1,ITSN1,GPAM,ZCCHC17,NLGN1,PAAF1,PDE8B,SCG3,ASPH,NMNAT2,ADAM15,CASTOR3,CAMTA1,NODAL,CAMK2G,VXN,GRIA4,MFSD2A,INA,ZDHHC22,FNDC5,CHGA,PLEKHB1,CNTN1,MICAL2,OSBPL3,DZIP3,IGSF1,CTNND2,LRRTM3,BDNF-AS,COPS7A,AK5,NAV2,HS3ST4,SLC17A6,SLC25A18,SLC6A15,RGR" MicroRNA hsa-miR-188-3p:mirSVR_highEffct hsa-miR-188-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.40E-19 2.93E-15 2.19E-18 2.01E-17 56 1038 "SYT9,LGR4,MEG3,ARID1A,FGF14,ITSN1,NTNG1,CCDC88A,SORCS3,RCOR3,NRG3,CAB39,AHCYL1,ARPP21,KIF1B,ZNF302,GFAP,PCDH11X,DDHD2,ZEB1,PTBP2,VXN,GRIA2,GRIA4,CRB1,LGI1,TPD52,TPM3,MAGI1,PDE1C,PRMT8,CASC2,GDAP1L1,CADM1,NRXN2,CAMKV,MED1,SNCAIP,RBPJ,PRKACB,ECE2,MASP1,SYTL2,PRTFDC1,PTPRD,PTPRO,C1orf109,RABGAP1L,NAV2,RTN4,ABCC9,ZYG11B,RFX4,PIANP,FGFBP3,SLC4A10" MicroRNA hsa-miR-34c-5p:mirSVR_highEffct hsa-miR-34c-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.56E-19 3.01E-15 2.25E-18 2.07E-17 52 900 "LGR4,MDM4,GPR158,LRRC7,ELMOD1,HPCAL4,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,ZCCHC17,RUFY2,SORCS3,PALLD,B3GALT2,ARPP21,KIF1B,NCAM1,ARHGEF7,GNAS,DDHD2,CAMTA1,GOLGB1,ANO4,GRID1,INA,TNR,LGI1,TPD52,GDAP1L1,CADM1,CCSER2,ST8SIA5,SULT4A1,SLC25A27,IGSF1,CTNND2,NOS1AP,SYNC,LRRTM3,PTHLH,MAGI2,KCNA2,PTPRD,PEX5,TMEM255A,SLC6A15,JMJD1C,SYT15,VWA5A" MicroRNA hsa-miR-29a:PITA hsa-miR-29a:PITA_TOP PITA 5.58E-19 3.02E-15 2.26E-18 2.07E-17 42 583 "ASIC1,KCNIP2,SLITRK1,ANK3,PPM1E,GPAM,ZCCHC17,SCN3B,ERBIN,RND1,NFIA,CAMTA1,CAMSAP2,CACNA1A,EML4,CAMK2G,ZFP91,CDC42,RBFOX2,FNDC5,NLGN3,NEGR1,UBTF,CCSER2,CRMP1,OSBPL3,PRKAB2,ARHGEF4,CTNND1,NRSN1,FAM131B,WBP1L,TUBB2B,KCNMA1,PEX5,DLG2,NKAIN1,TMEM255A,FAM57B,ABI1,BSDC1,SH3GLB1" MicroRNA hsa-miR-29c:PITA hsa-miR-29c:PITA_TOP PITA 5.58E-19 3.02E-15 2.26E-18 2.07E-17 42 583 "ASIC1,KCNIP2,SLITRK1,ANK3,PPM1E,GPAM,ZCCHC17,SCN3B,ERBIN,RND1,NFIA,CAMTA1,CAMSAP2,CACNA1A,EML4,CAMK2G,ZFP91,CDC42,RBFOX2,FNDC5,NLGN3,NEGR1,UBTF,CCSER2,CRMP1,OSBPL3,PRKAB2,ARHGEF4,CTNND1,NRSN1,FAM131B,WBP1L,TUBB2B,KCNMA1,PEX5,DLG2,NKAIN1,TMEM255A,FAM57B,ABI1,BSDC1,SH3GLB1" MicroRNA hsa-miR-29b:PITA hsa-miR-29b:PITA_TOP PITA 5.58E-19 3.02E-15 2.26E-18 2.07E-17 42 583 "ASIC1,KCNIP2,SLITRK1,ANK3,PPM1E,GPAM,ZCCHC17,SCN3B,ERBIN,RND1,NFIA,CAMTA1,CAMSAP2,CACNA1A,EML4,CAMK2G,ZFP91,CDC42,RBFOX2,FNDC5,NLGN3,NEGR1,UBTF,CCSER2,CRMP1,OSBPL3,PRKAB2,ARHGEF4,CTNND1,NRSN1,FAM131B,WBP1L,TUBB2B,KCNMA1,PEX5,DLG2,NKAIN1,TMEM255A,FAM57B,ABI1,BSDC1,SH3GLB1" MicroRNA hsa-miR-142-5p:TargetScan hsa-miR-142-5p TargetScan 5.81E-19 3.15E-15 2.35E-18 2.16E-17 45 674 "RIMKLA,ARID1A,CSMD3,RTN1,MAGI3,GAS7,NSG2,ASCL1,MYT1L,CADM3,C11orf87,DCAF5,FAM168A,NFIA,LUZP2,CAMSAP2,GPR26,CAMK2A,RFFL,PAX6,REPS2,HEPACAM,CADM1,CNTN1,CELF5,PUM1,FAM131B,PROX1,ITGAV,CADM2,LRP8,RGMA,CEP170,MAGI2,KCNA4,PTPRD,KCNJ10,KCNK1,DLG2,CALN1,ATG16L1,GOPC,JMJD1C,CACNG7,ELAVL4" MicroRNA hsa-miR-34c-3p:mirSVR_highEffct hsa-miR-34c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.44E-19 3.49E-15 2.60E-18 2.39E-17 50 836 "RTN3,ADGRV1,LDLRAD3,ARID1A,LINC00461,FGF14,FHL1,MOBP,APC,NTNG1,MAGI3,SLITRK3,MIER1,CCDC88A,RCOR3,GABBR1,SON,MYT1L,SOX5,CAB39,NCAM1,ADGRL3,GPM6A,GPM6B,ACSL6,TCF7L2,GRIK2,GRM3,JAM2,CADM1,DNAJC12,MEAF6,PRRX1,CHD1L,RNF14,SNCAIP,ATRNL1,PRKACB,NRSN1,PSMD13,CEP170,SRGAP3,CAB39L,KIF2A,DPP6,ABI1,RFX4,FAM135B,RPRD1A,RCAN2" MicroRNA hsa-miR-154*:mirSVR_highEffct hsa-miR-154*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.51E-19 3.53E-15 2.63E-18 2.41E-17 55 1007 "WLS,CSMD3,AGT,KIAA1109,CDC42BPA,ITSN1,SH3GL2,MAGI3,API5,BCO1,ARFGAP2,YPEL4,ASTN1,MYT1L,KIF21B,GAD2,NPAS3,SPART,ERBIN,GLS,ZNF638,SYT4,GPM6A,ZEB1,EML4,GRIA4,REPS2,ANO5,TMEFF2,ST8SIA5,SPATA6,POU3F2,PPP3CB,KCNT2,ATRNL1,PRKACB,TOX,ANKS1B,CADM2,MAGI2,ZC3H11A,SMG7,PLPPR4,KCNC1,PCDH15,KCNMA1,FAM13C,DTNA,RFX5,JMJD1C,ZNF248,SEC61A2,RNF220,SSPN,TMEM100" MicroRNA hsa-miR-507:mirSVR_highEffct hsa-miR-507:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.80E-19 3.68E-15 2.74E-18 2.52E-17 55 1008 "FAM43B,SLC25A25,ERMN,SCN3A,LRRTM4,KIAA1109,BCAR3,FHL1,UNC79,MOG,SELL,AMPH,ANK2,PPFIA1,SESN3,ARFGAP2,SMARCE1,RCOR3,ATP2B2,B3GALT2,TTLL9,NEUROD1,GLS,NKX2-2,ANO4,PRUNE2,CACNB2,GRIA2,GRIK2,TMEM257,PAX6,PCDH9,RBFOX2,MAGI1,HNRNPK,KIAA1549L,NRXN1,MEAF6,BTF3L4,DZIP3,FMN2,PRKCZ,LRRTM3,OLFM3,PTPRD,PTPRO,KCNJ9,ABI1,DSCAM,DBX2,ABCC9,GPR61,FGFBP3,SLC4A10,ELAVL4" MicroRNA hsa-miR-4276:mirSVR_highEffct hsa-miR-4276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.08E-19 3.84E-15 2.85E-18 2.62E-17 57 1080 "ACER3,ADGRV1,EYA1,FAM43B,CSMD3,CDC7,FABP7,ERMN,LRRC7,SEMA6A,MOG,SELL,ANK3,PKP4,GPAM,CACHD1,NLGN1,PAAF1,MIER1,SLC1A6,ASPH,NASP,ZNF302,RGL1,GLS,DDHD2,GPM6A,GPM6B,NUDT21,VSTM2A,NUMA1,CRB1,LEFTY2,PAH,PAX6,CDC42,LGI1,PDE4B,TMEFF2,CADM1,NRXN1,ATCAY,CRLS1,SNCAIP,PLPP4,PKN2,USP54,TOMM20,OLFM3,SMG7,PTPRE,HS3ST4,RAP1GAP,ABI1,RGS7,SEC61A2,EPB41L2" MicroRNA hsa-miR-1298:mirSVR_lowEffct hsa-miR-1298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.96E-19 4.31E-15 3.21E-18 2.94E-17 56 1047 "EPS8,ATAT1,WAC,FABP7,SORCS1,TOMM40L,LRRTM4,ERICH3,SGIP1,PKP4,PPM1E,APC,TACC2,NLGN1,BCAS1,API5,PAAF1,CCDC88A,CAPRIN2,ASPH,ATP2B2,AHCYL1,KIF1B,ZNF302,ARHGEF7,LUZP2,B4GALNT4,ZEB1,EML4,GRIA4,GRID1,SEZ6L,CADM1,PRRX1,SPATA6,CP,VCAN,RBPJ,FMN2,NRSN1,FGFR1OP2,BRINP3,KLK6,ANKS1B,CA10,MAGI2,OLFM3,OCIAD1,SRGAP3,PID1,SLC17A6,FAM13C,DTNA,PAK5,VWA5A,EN2" MicroRNA hsa-miR-522:PITA hsa-miR-522:PITA_TOP PITA 8.24E-19 4.46E-15 3.31E-18 3.04E-17 39 503 "RTN3,BCAR3,PPM1E,RUFY2,ARHGAP5,ASCL1,CSPG5,RCOR3,SNAP25,PHYHIPL,WDTC1,AHCYL1,NMNAT2,NCAM1,LMO3,FGF17,NEUROD1,CECR2,PSD3,TMEM257,RBFOX2,TPM3,ZNF384,HNRNPK,TLX1,CADM1,NSD2,KCNT2,DOCK7,FGFR1OP2,TOX,CSDE1,ZC3H11A,KCNA1,KCNK2,DLG2,ST8SIA3,RBM12,ABI2" MicroRNA hsa-miR-550*:mirSVR_highEffct hsa-miR-550*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.24E-19 4.46E-15 3.31E-18 3.04E-17 39 503 "MAP6,TMEM74,ARID1A,KLRC4,GALNT13,SFPQ,CDC42BPA,SH3GL2,NTNG1,DGKZ,ZNF365,ATP1A2,MYT1L,ARPP21,NPAS3,SYT4,CAMSAP2,LILRA1,PRLHR,CRB1,INA,C1orf94,PCDH8,LGI1,ZBED5,TMEFF2,OPALIN,MEAF6,VCAN,PRDM2,PTPRE,KIF2A,DTNA,CRTAC1,FAM135B,TTLL7,SLC4A10,EPB41,RASGRP2" MicroRNA hsa-miR-1302:mirSVR_highEffct hsa-miR-1302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.98E-19 4.86E-15 3.61E-18 3.31E-17 48 777 "SYT9,GALNT13,ADD3,LRRTM4,LRRC7,MOBP,NTNG1,MAGI3,SLITRK3,SYBU,ZNF365,RCOR3,ATM,ATP2B2,ARPP21,KIF1B,ADGRB2,NELL1,SEPT3,FAM168A,NFIA,ARHGEF7,GLS,VAMP1,ZNF638,LUZP2,PRUNE2,ACSL6,INA,MAEL,PCDH9,TPM3,BEST3,TMEFF2,SLC36A4,CHD1L,MED1,FEZ1,KIAA1755,ZNF385B,HP1BP3,OCIAD1,SNX27,PYGM,C12orf4,ABI1,GNE,RGR" MicroRNA hsa-miR-2114:mirSVR_highEffct hsa-miR-2114:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.90E-19 5.36E-15 3.97E-18 3.65E-17 40 534 "SERPINA3,ZFYVE27,EXTL1,LDLRAD3,CSMD3,F3,TESK2,TACC2,NAXD,ASPH,WDTC1,KIF1B,BCL2L2,FGF17,RGL1,CACNB2,ZEB1,CECR2,GRIA4,MFSD2A,TPM3,PDYN,PRRX1,SLC36A4,CNRIP1,CHD1L,SNCAIP,KCNT2,CTNND1,SPIRE1,DNAJC6,PRDM2,C1orf109,RAB3IL1,RAD52,DBX2,RPRD1A,YY1AP1,RPE65,EPB41L2" MicroRNA hsa-miR-3134:mirSVR_highEffct hsa-miR-3134:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-18 5.47E-15 4.05E-18 3.72E-17 49 812 "ABAT,RTN3,ACTN2,CSMD3,ADORA3,ASIC4,MOG,SH3GL2,SLITRK3,NLGN1,ZNF365,BCO1,MSR1,SLC8A3,CADPS,SPHKAP,SLIT1,SMARCE1,NFASC,NCAM1,VAMP1,ANO4,NPPA,CACNB2,NUMA1,GRIA2,GRIA4,ADAMTS8,OLR1,LEFTY2,PCDH9,NRXN1,NECAB2,KIAA1755,PKN2,MAPK8,KIAA0408,TOX,ANKS1B,LRP8,ZC3H11A,SMG7,C1orf109,RABGAP1L,DLG2,CAB39L,DTNA,JMJD1C,LPAR6" MicroRNA hsa-miR-891b:mirSVR_highEffct hsa-miR-891b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-18 5.54E-15 4.10E-18 3.76E-17 52 913 "EPS8,FABP7,GPR158,ELMOD1,MOG,ANK2,FOLH1,PPFIA1,PPM1E,NTNG1,GPAM,NLGN1,BCAS1,API5,ZNF365,RUFY2,SLC8A2,CCDC88A,SMARCE1,DKK3,MYT1L,NMNAT2,NEK6,NELL1,GNAS,CAMSAP2,ANO4,TCF7L2,NUDT21,EML4,VXN,FBXL16,CDC42,HMGB1,ZFYVE9,TJP2,BTF3L4,P2RY12,NXPH1,PPP3CB,OSBPL3,ARHGEF4,NRSN1,TOX,SYTL2,PTPRD,KCNJ10,KLRC2,RFX4,SH3GLB1,ABI2,RPE65" MicroRNA hsa-miR-33a-5p:TargetScan hsa-miR-33a-5p TargetScan 1.06E-18 5.74E-15 4.25E-18 3.90E-17 35 399 "CEND1,MDM4,ADD3,FGF14,CDC42BPA,ANK3,NLGN1,LRRC4C,FYN,MYT1L,AHCYL1,KIF1B,NFIA,ANO4,CACNA1E,CAMK2G,GRIK2,GPR88,PDE3B,KIAA1549L,NRXN1,NOMO2,FTO,PACSIN1,SDC3,PLD5,MAPK8,CADM2,RGMA,KCND3,KCNK1,HS3ST4,CALN1,ABI2,EN2" MicroRNA hsa-miR-33b-5p:TargetScan hsa-miR-33b-5p TargetScan 1.06E-18 5.74E-15 4.25E-18 3.90E-17 35 399 "CEND1,MDM4,ADD3,FGF14,CDC42BPA,ANK3,NLGN1,LRRC4C,FYN,MYT1L,AHCYL1,KIF1B,NFIA,ANO4,CACNA1E,CAMK2G,GRIK2,GPR88,PDE3B,KIAA1549L,NRXN1,NOMO2,FTO,PACSIN1,SDC3,PLD5,MAPK8,CADM2,RGMA,KCND3,KCNK1,HS3ST4,CALN1,ABI2,EN2" MicroRNA hsa-miR-520f:PITA hsa-miR-520f:PITA_TOP PITA 1.09E-18 5.88E-15 4.34E-18 3.98E-17 37 452 "LGR4,SLITRK1,AMER2,LRRTM4,ANK1,ITSN1,MAGI3,SLITRK3,RCOR3,ATP2B2,SOX5,LMO3,RGL1,ARHGEF7,CAMSAP2,OMG,OPCML,TNS1,PCDH9,RBFOX2,LGI1,FAT3,ACBD5,PKN2,TOX,SYNC,SIRPA,RGMA,ZC3H11A,OLFM3,PTPRD,HS3ST4,WIPF2,FAM13C,PAK5,RET,VANGL2" MicroRNA hsa-miR-92b*:mirSVR_lowEffct hsa-miR-92b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-18 5.88E-15 4.34E-18 3.98E-17 37 452 "ADORA1,FCGR1A,FCGR1B,SNX32,PKP4,BCAN,ST3GAL3,BCAS1,CLSTN1,ARFGAP2,ARFGAP1,ASPH,ZSWIM8,ADGRB2,NKX2-2,KAZN,CAMTA1,CNTN2,TCF7L2,CLEC9A,ZDHHC22,HRH3,TMPRSS5,PFKFB3,JAM2,CABP1,PACSIN1,PTPA,MICAL2,ATRNL1,PRKCG,PLPP4,SMG7,KCNMA1,PYGM,DNM2,RASGRF1" MicroRNA hsa-miR-506:mirSVR_highEffct hsa-miR-506:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.12E-18 6.08E-15 4.48E-18 4.11E-17 57 1091 "EPS8,PRR5L,ADGRV1,RYR1,ERMN,SLC44A5,SEMA6A,ANXA7,NTNG1,MAGI3,SLITRK3,BCO1,MSRA,CAPRIN2,SMARCE1,ATP2B2,PALLD,ZCCHC24,NEK6,MYRF,ANO4,PTBP2,CECR2,NUMA1,GRIA2,GRIA4,GRID1,LINC00839,USP2,TMEM257,KCNK10,PCDH8,PCDH9,PDE4B,TUB,GDAP1L1,TJP2,CNTN1,PRRX1,ETNPPL,CHD1L,SNCAIP,PPP3CB,VCAN,PKN2,CTNND1,EDRF1,OCIAD1,PTPRD,C1orf109,PTPRZ1,KCNK2,KIF2A,DTNA,RFX4,JMJD1C,VWA5A" MicroRNA hsa-miR-32:PITA hsa-miR-32:PITA_TOP PITA 1.15E-18 6.21E-15 4.57E-18 4.20E-17 38 480 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-212:mirSVR_highEffct hsa-miR-212:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.15E-18 6.24E-15 4.59E-18 4.21E-17 53 950 "PRR5L,CNTNAP3,LGR4,ARID1A,RTKN,KCNIP2,SCN3A,LRRTM4,SEMA6A,NTNG1,MAGI3,BCAN,API5,SHTN1,MIER1,ARFGAP2,PDE8B,CAPRIN2,RCOR3,DKK3,SON,SOX5,ILDR2,IDI2-AS1,C11orf87,NDUFA5,ERBIN,SEMA4A,CAMSAP2,ADGRL3,TMEM136,PTBP2,GRIA2,GRM3,JAM2,SERPINE2,CCSER2,ETNPPL,PPP2R5C,LRRTM3,CSDE1,PTPRD,SV2A,KCNK2,PCDH15,GNE,FAM13C,DTNA,RTN4,RFX4,CBLN2,RAVER2,EPB41" MicroRNA hsa-miR-1305:PITA hsa-miR-1305:PITA_TOP PITA 1.17E-18 6.33E-15 4.66E-18 4.27E-17 37 453 "CLIP1,ACTL6B,PPM1E,NTNG1,SORCS3,ATP2B2,PALLD,SON,MYBPC1,NFIA,CAMSAP2,CAMK2A,GRIA4,TMEM257,ZFP91,REPS2,PCDH9,PFKFB3,CCSER2,BTF3L4,NXPH1,PPP3CB,RIMS4,KIAA0408,TOX,JAKMIP2,CADM2,CEP170,KCNA1,SMG7,KCNMA1,TMEM255A,JMJD1C,SEC61A2,RBM12,EN2,RCAN2" MicroRNA hsa-miR-488:PITA hsa-miR-488:PITA_TOP PITA 1.19E-18 6.45E-15 4.75E-18 4.35E-17 32 326 "ARID1A,CSMD3,ANK3,CCDC88A,TMEM151A,MYT1L,CPLX2,ERBIN,NFIA,POPDC3,CAMTA1,CAMSAP2,PTBP2,CELF3,ZFP91,REPS2,CDC42,RBFOX2,LGI1,PDE4B,HMGB1,PFKFB3,HEPACAM,CADM1,TENM4,PKN2,PLD5,CEP170,PEX5,SNX27,DLG2,PHC2" MicroRNA hsa-miR-23a*:mirSVR_lowEffct hsa-miR-23a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-18 6.60E-15 4.85E-18 4.45E-17 57 1093 "ZFYVE27,SRARP,MEG3,ATAT1,RTKN,SLC25A25,TMEM156,TOMM40L,FGF1,FOXM1,CNIH2,ITSN1,ZCCHC17,NLGN1,CCDC88A,ASTN1,TMEM108,SNCB,WDTC1,CADM3,ENKUR,EMC1,ADGRB2,SPART,ALDH1L1,GLS,OS9,TBX15,ZEB1,PSD3,GRIA1,GRIA2,GRIA4,HPS5,BEST3,CPT1C,CELF5,BEST1,ATCAY,PNKD,PPP3CB,DOCK7,KIAA1755,PRKCZ,TOX,SPIRE1,PSMD13,JAKMIP2,PTPRD,PLPPR4,SV2A,KCNJ10,CAB39L,PARP11,DTNA,L1CAM,EPB41L1" MicroRNA hsa-miR-320a:PITA hsa-miR-320a:PITA_TOP PITA 1.23E-18 6.66E-15 4.88E-18 4.47E-17 38 481 "EYA1,WLS,ERMN,SEMA6A,SLITRK3,TACC2,SHTN1,ARHGAP5,TMEM108,PALLD,MYT1L,CAB39,DNER,LMO3,NCDN,CAMTA1,CAMSAP2,BTRC,VXN,GPR88,ZFP91,TPM3,TPM4,CHGA,NEGR1,MED1,RIMS4,FAM131B,TOX,PRTFDC1,CDH20,SMG7,DLG2,TMEM255A,CALN1,SLC17A6,PAK5,GPR61" MicroRNA hsa-miR-320d:PITA hsa-miR-320d:PITA_TOP PITA 1.23E-18 6.66E-15 4.88E-18 4.47E-17 38 481 "EYA1,WLS,ERMN,SEMA6A,SLITRK3,TACC2,SHTN1,ARHGAP5,TMEM108,PALLD,MYT1L,CAB39,DNER,LMO3,NCDN,CAMTA1,CAMSAP2,BTRC,VXN,GPR88,ZFP91,TPM3,TPM4,CHGA,NEGR1,MED1,RIMS4,FAM131B,TOX,PRTFDC1,CDH20,SMG7,DLG2,TMEM255A,CALN1,SLC17A6,PAK5,GPR61" MicroRNA hsa-miR-320c:PITA hsa-miR-320c:PITA_TOP PITA 1.23E-18 6.66E-15 4.88E-18 4.47E-17 38 481 "EYA1,WLS,ERMN,SEMA6A,SLITRK3,TACC2,SHTN1,ARHGAP5,TMEM108,PALLD,MYT1L,CAB39,DNER,LMO3,NCDN,CAMTA1,CAMSAP2,BTRC,VXN,GPR88,ZFP91,TPM3,TPM4,CHGA,NEGR1,MED1,RIMS4,FAM131B,TOX,PRTFDC1,CDH20,SMG7,DLG2,TMEM255A,CALN1,SLC17A6,PAK5,GPR61" MicroRNA hsa-miR-320b:PITA hsa-miR-320b:PITA_TOP PITA 1.23E-18 6.66E-15 4.88E-18 4.47E-17 38 481 "EYA1,WLS,ERMN,SEMA6A,SLITRK3,TACC2,SHTN1,ARHGAP5,TMEM108,PALLD,MYT1L,CAB39,DNER,LMO3,NCDN,CAMTA1,CAMSAP2,BTRC,VXN,GPR88,ZFP91,TPM3,TPM4,CHGA,NEGR1,MED1,RIMS4,FAM131B,TOX,PRTFDC1,CDH20,SMG7,DLG2,TMEM255A,CALN1,SLC17A6,PAK5,GPR61" MicroRNA hsa-miR-145:PITA hsa-miR-145:PITA_TOP PITA 1.24E-18 6.73E-15 4.93E-18 4.52E-17 35 401 "RTKN,CSMD3,ADD3,TOMM40L,SCN3A,SEMA6A,NLGN1,SLC1A2,ARHGAP5,SLN,SON,AHCYL1,GFRA1,GANAB,CAMSAP2,TBX15,PSD3,TJP1,TPM3,UBTF,CABP1,CTNND1,ELMO1,MAGI2,ZC3H11A,KCNA1,KCNA4,KCNK1,SNX27,HS3ST4,TMEM255A,PAK5,RGS7,EFNA3,SLC4A10" MicroRNA hsa-miR-602:mirSVR_lowEffct hsa-miR-602:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-18 6.96E-15 5.09E-18 4.67E-17 40 538 "ADGRV1,ATAT1,KCNIP2,ASIC4,FHL1,PDZD4,FOXM1,TRIM46,ITSN1,PKP4,SORBS1,SLC1A7,LGI3,ADGRA1,EIF4G3,USP33,CADM3,TTLL9,ALDH1L1,ARHGEF7,DCLK2,NKX2-2,GPM6A,TCF12,SYT6,TMEM9,PCDH8,SEZ6L,PDE4B,CCSER2,SPATA6,PTPA,TENM4,PRKACB,PUM1,SPIRE1,SV2A,HS3ST4,RNF220,RCAN2" MicroRNA hsa-miR-509-3p:mirSVR_highEffct hsa-miR-509-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-18 7.16E-15 5.24E-18 4.80E-17 42 597 "WLS,CLIP1,CDC7,GPR158,SFPQ,JAKMIP3,SLC1A6,SLC2A5,MSRA,SCMH1,SORCS3,ATM,AHCYL1,ARPP21,CLASP2,GANAB,MMD2,TCF7L2,PTBP2,CAMK2A,GRIK2,ZFP91,PCDH9,TMEFF2,SEMA5B,ST8SIA5,NXPH1,PPP2R5C,ATRNL1,PRKACB,IGSF1,MASP1,BRINP3,SPIRE1,TUBB2B,ZC3H11A,NTM,RABGAP1L,PCDH15,KCNMA1,ZYG11B,SEC61A2" MicroRNA hsa-miR-656:PITA hsa-miR-656:PITA_TOP PITA 1.43E-18 7.76E-15 5.67E-18 5.20E-17 44 659 "EYA1,WLS,SCN3A,LRRC7,SOX6,SFPQ,SGIP1,PPM1E,SLITRK3,API5,AQP4,CCDC88A,SCG3,SNAP25,PALLD,CLASP2,CACNB2,PSD3,TLL2,TNR,TNS1,PCDH9,PCSK2,MAGI1,KIAA1549L,NRXN1,NEGR1,CCSER2,BTF3L4,PRRX1,PTCH1,CADM2,COPS7A,MAGI2,PTPRD,KCNJ10,DLG3,CAB39L,SLC17A6,PLEKHB2,ABI1,RFX5,OLIG2,RCAN2" MicroRNA hsa-miR-1279:mirSVR_highEffct hsa-miR-1279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-18 8.48E-15 6.19E-18 5.68E-17 51 888 "SDE2,LGR4,RTN3,CSMD3,KLHL32,LINC00461,FGR,ZCCHC17,TACC2,NLGN1,ARHGAP5,DACH2,SLCO1A2,SMARCE1,ATM,ILDR2,GPR162,SEPT3,ADGRL3,ANO4,PRLHR,TCF12,GPR88,HPS5,PCDH9,LGI1,TPD52,MAGI1,BEST3,MS4A7,OPALIN,CNTN1,SLC25A27,ETNPPL,KCNT2,ATRNL1,RBPJ,PRKACB,PLD5,USP54,ZNF385B,PTCH1,STMN4,OCIAD1,SMG7,PCDH15,TMEM255A,ABI1,DBX2,JMJD1C,FAM135B" MicroRNA hsa-miR-363:PITA hsa-miR-363:PITA_TOP PITA 1.74E-18 9.43E-15 6.88E-18 6.31E-17 38 486 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-92b:PITA hsa-miR-92b:PITA_TOP PITA 1.87E-18 1.01E-14 7.35E-18 6.74E-17 38 487 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-92a:PITA hsa-miR-92a:PITA_TOP PITA 1.87E-18 1.01E-14 7.35E-18 6.74E-17 38 487 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-25:PITA hsa-miR-25:PITA_TOP PITA 1.87E-18 1.01E-14 7.35E-18 6.74E-17 38 487 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-367:PITA hsa-miR-367:PITA_TOP PITA 1.87E-18 1.01E-14 7.35E-18 6.74E-17 38 487 "SDE2,CSMD3,DSCAML1,GRAMD1B,SCN3A,KIAA1109,FOXG1,ANK3,USP28,SESN3,TACC2,PALLD,DKK3,MYT1L,B3GALT2,RGL1,NFIA,PCDH11X,CAMTA1,GPM6A,CAMK2A,GRIA1,KCNK10,CDH10,CCSER2,FMN2,SIRPA,ITGAV,KCNA1,PTPRD,PTPRO,DLG2,TMEM255A,SLC17A6,PLEKHB2,BSDC1,INSYN2,SLC4A10" MicroRNA hsa-miR-1244:PITA hsa-miR-1244:PITA_TOP PITA 1.88E-18 1.02E-14 7.41E-18 6.79E-17 29 262 "EYA1,GALNT13,ADD3,SORCS1,BCAR3,FOXM1,CNIH2,NTNG1,PHYHIPL,CADM3,CLASP2,FAM168A,NFIA,BTRC,EML4,GRIA4,MAEL,REPS2,DCLK1,SERPINE2,RAB39A,MAPK8,FGFR1OP2,TOX,PTPRD,KCNMA1,RAD52,RBM12,SH3GLB1" MicroRNA hsa-miR-1243:mirSVR_highEffct hsa-miR-1243:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.94E-18 1.05E-14 7.61E-18 6.98E-17 56 1068 "EYA1,ARID1A,RTKN,NDRG2,BCO1,CCDC88A,CADPS,RCOR3,NRG3,TNIK,SOX10,GAD2,AHCYL1,B4GALNT1,RGL1,NEUROD1,SYT4,LUZP2,NODAL,KLHL4,PRUNE2,CACNB2,ZEB1,PTBP2,GRIA2,GRIK4,CRB1,TMEM9,TMEM257,CDC42,PCDH9,NLGN3,NRXN1,SEMA5B,A2ML1,CCSER2,CNTN1,PMP2,SLC36A4,SNCAIP,KCNT2,ATRNL1,DOCK7,CTNND2,GON4L,PLPPR5,PTCH1,DNAJC6,MAGI2,PTPRE,KCNMA1,PLEKHB2,DTNA,RET,SEC61A2,SSPN" MicroRNA hsa-miR-1271:PITA hsa-miR-1271:PITA_TOP PITA 1.97E-18 1.07E-14 7.73E-18 7.09E-17 33 356 "ABAT,SLC25A25,SNX30,LRRC7,SEMA6A,SOX6,TRIM46,MAGI3,BRINP2,FYN,B3GALT2,SOX5,B4GALNT1,RAP1GAP2,CAMTA1,CDK5R2,TBX15,GPM6A,GRIA1,GRID1,MAGI1,NRXN1,ANLN,CABP1,MED1,RIMS4,CTNND1,PMEPA1,CEP170,ATG16L1,BSDC1,JMJD1C,SLC4A10" MicroRNA hsa-miR-496:mirSVR_highEffct hsa-miR-496:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-18 1.11E-14 8.01E-18 7.35E-17 52 928 "RTN3,ACTN2,TMEM156,FCGR1A,SCN3A,BCAR3,SLC30A10,ANK3,ITSN1,MAGI3,ZNF365,SLC1A6,SLC14A1,ASPH,SMARCE1,EIF4G3,PHYHIPL,MYT1L,ARPP21,GART,SMOC1,NEUROD1,FAM168A,CNDP1,EML4,GRIA4,PAH,PAX6,PCDH9,PDE1A,HMGB1,MS4A7,TMEFF2,NRXN1,NRXN2,MEAF6,BEST1,P2RY12,MFSD4A,CRMP1,PRKACB,ITGAV,PRTFDC1,PTPRE,RABGAP1L,TMEM255A,DTNA,RET,ZNF248,RNF220,RBM12,SLC4A10" MicroRNA hsa-miR-576-5p:PITA hsa-miR-576-5p:PITA_TOP PITA 2.08E-18 1.13E-14 8.17E-18 7.50E-17 36 434 "FABP7,FGF1,SOX6,DGKD,ARHGAP5,SCG3,PHYHIPL,MEGF11,MYT1L,KIF1B,DCAF5,NEUROD1,CAMSAP2,ZEB1,PCSK2,KIAA1549L,NRXN1,NEGR1,CCSER2,FAT3,PKN2,KIAA0408,TOX,SYTL2,PTCH1,ITGAV,PMEPA1,PRTFDC1,KCNA4,PTPRE,KCNMA1,DLG2,SLC17A6,DSCAM,RGS7,ARHGAP12" MicroRNA hsa-miR-543:PITA hsa-miR-543:PITA_TOP PITA 2.12E-18 1.15E-14 8.30E-18 7.61E-17 41 575 "EPS8,EYA1,DOCK10,SLITRK3,API5,SNAP25,MEGF11,CAB39,NPAS3,LMO3,RGL1,SEPT3,NKX2-2,CAMTA1,CAMK2G,GRIK2,DCLK1,MAGI1,NEGR1,NMT2,FAT3,NXPH1,SF1,OSBPL3,DOCK7,PROX1,TOX,SIRPA,PTCH1,ZC3H11A,KCNA1,PTPRD,SMG7,PTPRE,ARNT2,KCNMA1,PID1,PAK5,SH3GLB1,LMO1,EN2" MicroRNA hsa-miR-3155:mirSVR_highEffct hsa-miR-3155:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.13E-18 1.15E-14 8.34E-18 7.65E-17 44 666 "TTYH1,ACHE,RTN3,ERMN,ADORA3,TOMM40L,FGF1,FHL1,TRIM46,ANK1,TNIK,SOX5,ZCCHC24,INKA2,GANAB,GOLGB1,NUMA1,GRIA4,RFFL,GRIN1,CYB561A3,CRB1,TGFBR3,MFSD2A,CDK11B,PADI2,MAGI1,FNDC5,DNAJC12,PLXNB3,ACBD5,SNCAIP,NCAN,DOCK7,PKN2,MAPK10,BDNF-AS,PTPRE,PTPRZ1,RABGAP1L,DNM2,BSDC1,ARHGEF10L,SLC4A10" MicroRNA hsa-miR-367*:mirSVR_highEffct hsa-miR-367*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-18 1.23E-14 8.91E-18 8.17E-17 50 862 "RTN3,DRAXIN,TOMM40L,TRIM46,PPFIA1,NLGN1,MIER1,SLC8A3,SMARCE1,RCOR3,PHYHIPL,SON,TNIK,FXYD6,ERBIN,DCAF5,NELL1,SEPT3,FAM168A,CASTOR3,GNAS,ADGRL3,ZEB1,DIRAS1,AZIN2,PTBP2,CRB1,TPM3,PCSK2,PDE4B,ZFYVE9,SULT4A1,CHD1L,MED1,RNF14,MICAL2,NOS1AP,TOMM20,LRRTM3,PSMD13,OCIAD1,PCDH15,DLG2,SLC25A48,ATG16L1,ZYG11B,PHC2,RNF220,SSPN,RAVER2" MicroRNA hsa-miR-96:PITA hsa-miR-96:PITA_TOP PITA 2.33E-18 1.26E-14 9.11E-18 8.36E-17 33 358 "ABAT,SLC25A25,SNX30,LRRC7,SEMA6A,SOX6,TRIM46,MAGI3,BRINP2,FYN,B3GALT2,SOX5,B4GALNT1,RAP1GAP2,CAMTA1,CDK5R2,TBX15,GPM6A,GRIA1,GRID1,MAGI1,NRXN1,ANLN,CABP1,MED1,RIMS4,CTNND1,PMEPA1,CEP170,ATG16L1,BSDC1,JMJD1C,SLC4A10" MicroRNA hsa-miR-93-5p:Functional MTI Functional MTI miRTarbase 2.34E-18 1.27E-14 9.16E-18 8.40E-17 60 1220 "CDHR1,ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,GPAM,SYBU,USP16,RUFY2,CAPRIN2,GABBR1,SON,EMC1,SALL3,BCL2L2,SMOC1,ARHGEF7,LUZP2,GNAS,CAMTA1,WWC1,PRUNE2,TCF7L2,MFSD2A,ZFP91,TPM4,ZNF384,PDE3B,HMGB1,ZFYVE9,CCSER2,BTF3L4,NSD2,ACBD5,FEZ2,PRKACB,DZIP3,KIAA0513,CADM2,CEP170,CSDE1,OCIAD1,SMG7,KCND3,RABGAP1L,WIPF2,RAB5B,ATG16L1,RNF220,SFXN5,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100,ATP6V1G2-DDX39B" MicroRNA hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 2.44E-18 1.32E-14 9.54E-18 8.75E-17 32 334 "MAPT,APC2,EYA1,GRAMD1B,ANXA7,NTNG1,ATP1A2,PHYHIPL,ILDR2,NEK6,NPAS3,LMO3,NFIA,NHLH1,OS9,CACNA1E,GPR26,CAMK2G,CECR2,GRIK3,REPS2,HEPACAM,FADS2,FTO,PPP2R5C,HES5,DNAJC6,CADM2,KCNA4,DLG2,GPR61,ABI2" MicroRNA hsa-miR-520f-3p:TargetScan hsa-miR-520f-3p TargetScan 2.63E-18 1.42E-14 1.03E-17 9.41E-17 38 492 "RIMKLA,LGR4,AMER2,ANK2,MIER1,EIF4G3,ATP2B2,LMO3,RGL1,ACSBG1,NFIA,ARHGEF7,LUZP2,CAMSAP2,MYRF,PTBP2,OPCML,LEFTY2,KCNK10,RBFOX2,LGI1,MAGI1,CCSER2,IFFO1,FAT3,ACBD5,CRLS1,RBPJ,PKN2,KIAA0513,CADM2,LRP8,RGMA,OLFM3,PTPRD,DLG3,HS3ST4,FAM13C" MicroRNA hsa-miR-302c-3p.2:TargetScan hsa-miR-302c-3p.2 TargetScan 2.63E-18 1.42E-14 1.03E-17 9.41E-17 38 492 "RIMKLA,LGR4,AMER2,ANK2,MIER1,EIF4G3,ATP2B2,LMO3,RGL1,ACSBG1,NFIA,ARHGEF7,LUZP2,CAMSAP2,MYRF,PTBP2,OPCML,LEFTY2,KCNK10,RBFOX2,LGI1,MAGI1,CCSER2,IFFO1,FAT3,ACBD5,CRLS1,RBPJ,PKN2,KIAA0513,CADM2,LRP8,RGMA,OLFM3,PTPRD,DLG3,HS3ST4,FAM13C" MicroRNA hsa-miR-502-3p:mirSVR_highEffct hsa-miR-502-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-18 1.49E-14 1.07E-17 9.85E-17 39 521 "NDRG2,F3,FCGR1A,NTNG1,GPAM,SLITRK3,TACC2,ST3GAL3,JAKMIP3,ASPH,RCOR3,AHCYL1,ARPP21,NPAS3,PCDH11X,DDHD2,CACNB2,PTBP2,GRIA2,INA,PCDH9,PDE3B,GDAP1L1,CADM1,RNF14,KCNT2,RBPJ,PRKCZ,ECE2,SIRPA,BDNF-AS,PTHLH,HP1BP3,CSDE1,CCDC3,PCDH15,DBX2,SLC6A15,UEVLD" MicroRNA hsa-miR-101-3p.1:TargetScan hsa-miR-101-3p.1 TargetScan 2.81E-18 1.52E-14 1.10E-17 1.01E-16 44 671 "ASIC1,EYA1,ARID1A,MDM4,ANK3,PPFIA1,APC,MAGI3,JAKMIP3,ATP2B2,SCN3B,ARPP21,LMO3,C11orf87,GFRA1,NEUROD1,AJAP1,FAM168A,CAMSAP2,CACNB2,CAMK2G,BRSK2,PSD3,PTPN5,PCDH8,CDH8,MAGI1,DLGAP3,CADM1,NEGR1,PRRX1,FAT3,PROX1,PTCH1,JAKMIP2,RGMA,MAGI2,KCNA1,KCND3,KCNN3,KIF2A,RASGRF1,ABI2,EPB41L1" MicroRNA "TATTATA,MIR-374:MSigDB" "TATTATA,MIR-374:MSigDB" MSigDB 2.85E-18 1.54E-14 1.11E-17 1.02E-16 29 266 "ABAT,EYA1,CSMD2,SLITRK1,FOXG1,SYBU,NLGN1,ARHGAP5,ASCL1,TMEM108,ZCCHC24,C11orf87,NKX2-2,CAMSAP2,GPM6A,TCF12,PDE4B,ANLN,SF1,BRINP3,PMEPA1,PLPPR4,NTM,RALGDS,GOPC,PAK5,BSDC1,RFX4,SEZ6" MicroRNA hsa-miR-675*:mirSVR_highEffct hsa-miR-675*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.96E-18 1.60E-14 1.15E-17 1.06E-16 40 551 "MBP,MDM4,CSMD3,ADAR,KLHL32,GALNT13,TOMM40L,CDC42BPA,USP28,PKP4,APC,SHTN1,CSPG5,SPHKAP,ASPH,SMARCE1,RCOR3,LMO3,NDUFA5,AJAP1,FAM69C,ZEB1,TCF12,PTBP2,MAGI1,TMEFF2,NXPH1,CP,ATRNL1,VCAN,PLPP4,PLD5,KCNA4,PTPRO,SLC17A6,DBX2,ABCC9,SLC6A15,ZYG11B,VWA5A" MicroRNA hsa-miR-218-2*:mirSVR_highEffct hsa-miR-218-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.03E-18 1.64E-14 1.18E-17 1.08E-16 48 801 "RABEPK,ACER3,MDM4,WAC,FABP7,TMEM156,LINC00461,FGF1,PPFIA1,PKP4,CACHD1,RUFY2,SPHKAP,BRINP2,PHYHIPL,WDTC1,CADM3,DNER,RND1,FAM168A,SYT4,DCLK2,CACNA1E,ZEB1,PTBP2,AKNA,SPX,PAH,CDH8,TPM3,CA14,CADM1,A2ML1,BEST1,NXPH1,SNCAIP,PPP3CB,VCAN,DOCK7,STMN4,ZC3H11A,CAB39L,KIF2A,DNAH9,SUSD4,SLC6A15,RBM12,RCAN2" MicroRNA hsa-miR-1178:mirSVR_highEffct hsa-miR-1178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.06E-18 1.66E-14 1.19E-17 1.09E-16 45 704 "EPS8,MEG3,ATAT1,ADD3,LRRTM4,ANK3,PKP4,NTNG1,GPAM,TACC2,API5,EIF4G3,SON,WDTC1,ARPP21,GLS,PCDH11X,GNAS,TBX15,GPM6A,GRIA2,GRIA4,GRIN1,LEFTY2,MFSD2A,TPM3,PRMT8,ZMYND8,A2ML1,ACBD5,POU3F2,RNF14,PPP3CB,NOS1AP,PROX1,LRRTM3,PMEPA1,RGMA,MAGI2,PAK5,SLC6A15,ZYG11B,RFX4,INSYN2,SLC4A10" MicroRNA "CACTGCC,MIR-449:MSigDB" "CACTGCC,MIR-449:MSigDB" MSigDB 3.16E-18 1.71E-14 1.23E-17 1.12E-16 29 267 "MAPT,LGR4,PLEKHG5,ELMOD1,FOXG1,ANK2,PPFIA1,ITSN1,PKP4,DGKZ,ZCCHC17,LRRC55,SPHKAP,CPLX2,SEPT3,SYT4,CAMTA1,CNTN2,TCF12,GRID1,CELF3,TPD52,GDAP1L1,NRXN2,SEMA5B,RIMS4,CTNND2,TMEM255A,RALGDS" MicroRNA "CACTGCC,MIR-34C:MSigDB" "CACTGCC,MIR-34C:MSigDB" MSigDB 3.16E-18 1.71E-14 1.23E-17 1.12E-16 29 267 "MAPT,LGR4,PLEKHG5,ELMOD1,FOXG1,ANK2,PPFIA1,ITSN1,PKP4,DGKZ,ZCCHC17,LRRC55,SPHKAP,CPLX2,SEPT3,SYT4,CAMTA1,CNTN2,TCF12,GRID1,CELF3,TPD52,GDAP1L1,NRXN2,SEMA5B,RIMS4,CTNND2,TMEM255A,RALGDS" MicroRNA "CACTGCC,MIR-34A:MSigDB" "CACTGCC,MIR-34A:MSigDB" MSigDB 3.16E-18 1.71E-14 1.23E-17 1.12E-16 29 267 "MAPT,LGR4,PLEKHG5,ELMOD1,FOXG1,ANK2,PPFIA1,ITSN1,PKP4,DGKZ,ZCCHC17,LRRC55,SPHKAP,CPLX2,SEPT3,SYT4,CAMTA1,CNTN2,TCF12,GRID1,CELF3,TPD52,GDAP1L1,NRXN2,SEMA5B,RIMS4,CTNND2,TMEM255A,RALGDS" MicroRNA hsa-miR-140-5p:mirSVR_highEffct hsa-miR-140-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.17E-18 1.72E-14 1.23E-17 1.13E-16 50 869 "RABEPK,MEG3,ATAT1,RTKN,CSMD3,RTN1,SORCS1,AMER2,CHST15,LINC00461,KIAA1109,ELMOD1,ANK2,NLGN1,ZNF365,MIER1,CADPS,DKK3,SOX1,TTLL9,STOX1,PCDH11X,DDHD2,PSRC1,ADGRL3,GPM6A,PRLHR,ZEB1,INA,CELF3,C1orf94,SEZ6L,PRMT8,FNDC5,NMT2,A2ML1,CNTN1,MEAF6,CP,SNCAIP,OSBPL3,PKN2,PROX1,ANKS1B,BDNF-AS,CEP170,PTPRO,ABCC9,SLC6A15,EPB41L2" MicroRNA hsa-miR-924:mirSVR_highEffct hsa-miR-924:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-18 1.72E-14 1.23E-17 1.13E-16 50 869 "ASIC1,DSCAML1,ERMN,C1orf61,APBA2,GPAM,ZCCHC17,CCDC88A,NAXD,SMARCE1,TMEM108,SNAP25,ARPP21,GART,NPAS3,DCAF5,SEPT3,SLCO1C1,ZNF638,POPDC3,ADGRL3,KLHL4,NUMA1,GRIA4,P2RX7,CDC42,PADI2,PDYN,BEST3,JAM2,GDAP1L1,SERPINE2,NRXN1,P2RY12,POU3F2,SNCAIP,TENM4,RGS6,DOCK7,CTNND1,SPIRE1,PSMD13,PTHLH,PTPRE,PCDH15,SUSD4,DSCAM,RFX4,RLBP1,SSPN" MicroRNA hsa-miR-25*:mirSVR_lowEffct hsa-miR-25*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-18 1.94E-14 1.39E-17 1.27E-16 46 739 "DPF1,MAG,SERPINA3,RTN3,SORCS1,MOG,ANK3,NTNG1,ST3GAL3,BCAS1,SFMBT2,DLL3,CAPRIN2,SORCS3,RCOR3,ATP2B2,TNIK,ZSWIM8,C11orf87,NHLH1,KAZN,GNAS,TCF7L2,GPR17,NUMA1,LINC00839,LEFTY2,TPM3,PFKFB3,ASIC3,DLGAP3,KIAA1549L,CCSER2,FTO,TENM4,NKAIN4,MICAL2,PLCH2,FMN2,PKN2,PRKCZ,CTNND1,HP1BP3,YY1AP1,EPB41,BAALC" MicroRNA hsa-miR-618:mirSVR_highEffct hsa-miR-618:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.60E-18 1.95E-14 1.39E-17 1.28E-16 56 1083 "LOC100128239,SLC25A25,CSMD3,CDC7,NLGN4X,SLC44A5,LRRC7,PKP4,LRRC4C,MIER1,CCDC88A,PHYHIPL,USP33,GAD2,ARPP21,DNER,FXYD6,ZNF302,HEPN1,GLS,GPM6A,CECR2,GRIA4,TMEM9,TJP1,MAEL,PAX6,MAGI1,PDYN,HMGB1,CASC2,GDAP1L1,NEGR1,A2ML1,CCSER2,SLC25A27,BTF3L4,MED1,PPP3CB,RAB39A,PRKCZ,NRSN1,DNAJC6,PMEPA1,PTHLH,MAGI2,PLPPR4,NTM,PCDH15,PLEKHB2,RTN4,SLC6A15,INSYN2,ATL1,RPRD1A,EPB41" MicroRNA "AAGCAAT,MIR-137:MSigDB" "AAGCAAT,MIR-137:MSigDB" MSigDB 3.65E-18 1.98E-14 1.41E-17 1.29E-16 26 205 "CSMD2,PPM1E,ST3GAL3,SHANK2,CADPS,ASPH,SON,MYBPC1,NFASC,NEUROD1,ARHGEF7,GPR88,CDC42,MED1,PPP3CB,RIMS4,RIMS3,SYNC,KCNA2,SRGAP3,NKAIN1,SLC17A6,RFX4,RBM12,CBLN2,RAVER2" MicroRNA hsa-miR-574-5p:Functional MTI Functional MTI miRTarbase 3.67E-18 1.99E-14 1.42E-17 1.30E-16 35 415 "NLGN4X,FGF14,SLITRK3,BCAS1,RPH3A,SON,SOX5,NMNAT2,KIF1B,GFRA1,NCDN,PCDH11X,FAM69C,ZEB1,TMEM151B,OLR1,KCNK10,TNR,GPR37L1,LRTM2,NLGN3,KIAA1549L,NRXN1,SPATA6,NCAN,MAPK10,PROX1,DPYSL5,DNAJC6,JAKMIP2,GNE,TTLL7,SSPN,ABI2,EN2" MicroRNA hsa-miR-3139:mirSVR_highEffct hsa-miR-3139:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.71E-18 2.01E-14 1.43E-17 1.31E-16 44 676 "SDE2,ACHE,FABP7,SLC44A5,SCN3A,FGF1,AMPH,PPFIA1,ITSN1,ZCCHC17,PKNOX2,SHANK2,DLL3,SNAP25,GAD2,NELL1,RGL1,ADHFE1,SLCO1C1,GPM6A,GPM6B,GRIA2,LINC00839,CRB1,TIE1,TMEM9,BEST3,TJP2,SF1,SNCAIP,OSBPL3,NCAN,GON4L,PRDM2,MED24,SMG7,C1orf109,NTM,PCDH15,PEX5,JMJD1C,RPRD1A,YY1AP1,EN2" MicroRNA "GCACTTT,MIR-106A:MSigDB" "GCACTTT,MIR-106A:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA "GCACTTT,MIR-106B:MSigDB" "GCACTTT,MIR-106B:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA "GCACTTT,MIR-20B:MSigDB" "GCACTTT,MIR-20B:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA "GCACTTT,MIR-519D:MSigDB" "GCACTTT,MIR-519D:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA "GCACTTT,MIR-17-5P:MSigDB" "GCACTTT,MIR-17-5P:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA "GCACTTT,MIR-20A:MSigDB" "GCACTTT,MIR-20A:MSigDB" MSigDB 3.80E-18 2.06E-14 1.46E-17 1.34E-16 40 555 "F3,WAC,ANK2,SLITRK3,SYBU,SLC1A2,SLC6A9,YPEL4,ATP1A2,ATP2B2,MYT1L,NPAS3,LMO3,BCL2L2,SMOC1,RGL1,NHLH1,CAMTA1,ZFP91,ZFYVE9,CCSER2,PRRX1,PSD,KIAA0513,DPYSL5,CA10,PTHLH,RGMA,OLFM3,PTPRO,SRGAP3,KCNJ10,KCNMA1,KCNQ2,RAB5B,DNM2,ATG16L1,FAM13C,PAK5,ARHGAP12" MicroRNA hsa-miR-873-5p.2:TargetScan hsa-miR-873-5p.2 TargetScan 3.85E-18 2.08E-14 1.48E-17 1.35E-16 33 364 "RTN3,CSMD2,KIAA1109,FGF1,FHL1,ELMOD1,MOG,FOXM1,ANK3,CCDC80,ASPH,CADM3,NPAS3,FGF17,DDHD2,DIRAS1,DDR2,BRSK2,PSD3,REPS2,HNRNPK,JAM2,CADM1,FTO,RIMS4,NOS1AP,RIMS3,PHYHIP,GON4L,PTAFR,KCNA1,DLG3,EPB41L1" MicroRNA hsa-miR-589:mirSVR_highEffct hsa-miR-589:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.10E-18 2.22E-14 1.57E-17 1.44E-16 42 616 "ZFYVE27,ACER3,TMEM74,SYT9,RTN3,RCSD1,ACTN2,MRVI1,NDRG2,SORCS1,AMER2,FCGR1A,GPR158,SESN3,ST3GAL3,BCAS1,AQP4,CADPS,ASPH,TMEM108,CLASP2,COLGALT2,PRUNE2,ZEB1,GRIK3,TNR,GPR37L1,SEMA5B,MFSD4A,CHD1L,RGS6,PKN2,TOX,DNAJC6,CEP170,PLPPR4,AK5,DSCAM,DTNA,L1CAM,RPRD1A,FGFBP3" MicroRNA hsa-miR-1238:mirSVR_lowEffct hsa-miR-1238:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-18 2.22E-14 1.57E-17 1.44E-16 55 1050 "SDE2,CEND1,MRVI1,CSMD2,KLRC4,SLC30A10,TRIM46,AMPH,RASA3,PPFIA1,ITSN1,PKP4,APBA2,CACHD1,NLGN1,BCAS1,PAAF1,NRG3,EIF4G3,ATP2B2,ARPP21,EMC1,ALDH1L1,RND1,ZNF638,DCLK2,CACNB2,PRLHR,ZEB1,TCF12,PTBP2,GRIA4,FBXL16,TNR,ZNF384,PDYN,MS4A7,PRRX1,NXPH1,CNRIP1,MASP1,WBP1L,BLOC1S6,PTPRE,HS3ST4,PID1,RASGRF1,FAM13C,DTNA,RFX4,SEC61A2,GPR61,ABI2,RAVER2,SLC4A10" MicroRNA hsa-miR-653-5p:TargetScan hsa-miR-653-5p TargetScan 4.34E-18 2.35E-14 1.66E-17 1.52E-16 36 444 "MDM4,KLRC4,SCN3A,APC,LRRC4C,ARHGAP5,PHYHIPL,MYT1L,B3GALT2,NMNAT2,NKX6-2,RND1,LUZP2,CECR2,PSD3,RFFL,OPCML,GUCY1A2,REPS2,ARHGAP19,LRTM2,CADM1,NEGR1,MED1,PRKAB2,DOCK7,KIAA0513,LRRTM3,AK5,KIF2A,RTN4,PIANP,RBM12,RPRD1A,EPB41L1,RCAN2" MicroRNA hsa-miR-28-5p:mirSVR_highEffct hsa-miR-28-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.42E-18 2.40E-14 1.69E-17 1.55E-16 43 648 "SDE2,ACHE,FABP7,SLC44A5,FGF1,AMPH,PPFIA1,ITSN1,PKNOX2,SHANK2,DLL3,SNAP25,TNIK,GAD2,NELL1,RGL1,ADHFE1,SLCO1C1,GPM6A,GPM6B,PTBP2,GRIA2,CCKBR,LINC00839,TMEM9,HNRNPK,TJP2,SNCAIP,OSBPL3,NCAN,ANKS1B,GON4L,PRDM2,MED24,SMG7,C1orf109,NTM,PCDH15,JMJD1C,RPRD1A,YY1AP1,EN2,LRRC23" MicroRNA hsa-miR-489:mirSVR_highEffct hsa-miR-489:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.53E-18 2.46E-14 1.73E-17 1.59E-16 51 911 "CNTNAP3,EYA1,KLHL32,TOMM40L,LRRC7,SEMA6A,MOBP,SELL,ERICH3,ANXA7,PKP4,MAGI3,NLGN1,ST3GAL3,SLC8A3,SCG3,SMARCE1,ATM,SON,ZSWIM8,EMC1,KIF1B,C11orf87,ANO4,CACNA1E,PTBP2,GRIK2,P2RX7,TLL2,TPM3,PDE1C,PDE4B,ZMYND8,PFKFB3,JAM2,NOMO2,PMP2,SLC25A27,MED1,OSBPL3,CTNND2,JAKMIP2,BDNF-AS,RABGAP1L,SLC17A6,PLEKHB2,C12orf4,FAM13C,PAK5,RFX4,SLC4A10" MicroRNA hsa-miR-514b-5p:mirSVR_highEffct hsa-miR-514b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.60E-18 2.49E-14 1.76E-17 1.61E-16 56 1089 "SDE2,ATAT1,MDM4,F3,CLIP1,SLITRK1,GPR158,FOXG1,SLITRK3,CCDC88A,NRG3,EIF4G3,MEGF11,CAB39,DCAF5,GLS,VAMP1,DCLK2,DDHD2,ADGRL3,KLHL4,GPM6B,ZEB1,VXN,CDC42,SEZ6L,PDE3B,PRMT8,GPR37L1,CHGA,CCSER2,TJP2,BTF3L4,PMS2,SLC36A4,RNF14,PPP2R5C,NCAN,DOCK7,PKN2,NOS1AP,FGFR1OP2,MASP1,SYTL2,ANKS1B,ITGAV,HP1BP3,KCNK1,DLG2,PID1,SLC6A15,ZYG11B,RET,SEC61A2,ELAVL3,UEVLD" MicroRNA hsa-let-7b:mirSVR_highEffct hsa-let-7b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.74E-18 2.56E-14 1.81E-17 1.66E-16 47 777 "ACER3,LGR4,ARID1A,MDM4,KLHL32,ERMN,MOBP,SESN3,PAAF1,RUFY2,GABBR1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,GNAS,ACSL6,CACNB2,ADAMTS8,GPR88,CRB1,TGFBR3,AIFM1,SLC25A27,BEST1,PRRX1,MFSD4A,MICAL2,OSBPL3,RBPJ,PLPP4,IGSF1,MASP1,SYNC,PRDM2,PTPRO,KCNJ11,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-634:PITA hsa-miR-634:PITA_TOP PITA 5.25E-18 2.84E-14 2.00E-17 1.84E-16 29 272 "RTN1,SLITRK1,SNX30,PALLD,LMO3,CLASP2,ERBIN,DCAF5,NEUROD1,ADGRL3,CAMK2A,CAMK2G,PSD3,CELF3,RBFOX2,KIAA1549L,FAT3,MED1,RGS6,OSBPL3,SYNC,PRDM2,SRGAP3,KCNK2,KCNMA1,DLG2,TMEM255A,ABI1,EPB41L1" MicroRNA hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA_TOP PITA 5.31E-18 2.88E-14 2.02E-17 1.85E-16 30 295 "LGR4,GPR158,LRRC7,ELMOD1,FOXG1,ANK3,ITSN1,PKP4,ZCCHC17,SOX10,CPLX2,SEPT3,CAMTA1,CNTN2,CACNA1E,TCF12,GRID1,INA,CELF3,TPD52,PDE4B,FNDC5,NRXN2,SLC25A27,CTNND2,SYNC,PTPRD,TMEM255A,RALGDS,RET" MicroRNA hsa-miR-449a:PITA hsa-miR-449a:PITA_TOP PITA 5.31E-18 2.88E-14 2.02E-17 1.85E-16 30 295 "LGR4,GPR158,LRRC7,ELMOD1,FOXG1,ANK3,ITSN1,PKP4,ZCCHC17,SOX10,CPLX2,SEPT3,CAMTA1,CNTN2,CACNA1E,TCF12,GRID1,INA,CELF3,TPD52,PDE4B,FNDC5,NRXN2,SLC25A27,CTNND2,SYNC,PTPRD,TMEM255A,RALGDS,RET" MicroRNA hsa-miR-34a:PITA hsa-miR-34a:PITA_TOP PITA 5.31E-18 2.88E-14 2.02E-17 1.85E-16 30 295 "LGR4,GPR158,LRRC7,ELMOD1,FOXG1,ANK3,ITSN1,PKP4,ZCCHC17,SOX10,CPLX2,SEPT3,CAMTA1,CNTN2,CACNA1E,TCF12,GRID1,INA,CELF3,TPD52,PDE4B,FNDC5,NRXN2,SLC25A27,CTNND2,SYNC,PTPRD,TMEM255A,RALGDS,RET" MicroRNA hsa-miR-449b:PITA hsa-miR-449b:PITA_TOP PITA 5.31E-18 2.88E-14 2.02E-17 1.85E-16 30 295 "LGR4,GPR158,LRRC7,ELMOD1,FOXG1,ANK3,ITSN1,PKP4,ZCCHC17,SOX10,CPLX2,SEPT3,CAMTA1,CNTN2,CACNA1E,TCF12,GRID1,INA,CELF3,TPD52,PDE4B,FNDC5,NRXN2,SLC25A27,CTNND2,SYNC,PTPRD,TMEM255A,RALGDS,RET" MicroRNA hsa-miR-1304:mirSVR_highEffct hsa-miR-1304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.50E-18 2.98E-14 2.09E-17 1.92E-16 47 780 "ACER3,ACLY,RTN3,MEG3,KLHL32,SCN3A,LRRTM4,LINC00461,LRRC7,ANK2,GPAM,CAPRIN2,SMARCE1,SOX5,JPH4,ADAM15,DNER,NFASC,AJAP1,GLS,PCDH11X,PRUNE2,CACNA1E,CACNB2,ZEB1,NUCB1,GRIA4,TIE1,CD81,ZNF384,JAM2,GDAP1L1,CCSER2,PRRX1,POU3F2,FEZ1,MICAL2,RAB39A,PLD5,SYTL2,COPS7A,KCNA2,KCNA6,KCNN3,SLC17A6,GOPC,EPB41L2" MicroRNA hsa-miR-584:mirSVR_highEffct hsa-miR-584:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.72E-18 3.10E-14 2.17E-17 1.99E-16 52 951 "DPF1,RABEPK,SYT9,ADARB2,AMER2,CHST15,GPR158,LRRC7,ANK1,ANK3,PPFIA1,MAGI3,AQP4,MSR1,CCDC88A,SHANK2,CADPS,PALLD,SON,DNER,NPAS3,SPART,GANAB,PCDH11X,PSRC1,ZEB1,GRIA1,GRIK3,TNR,PCDH9,CDH8,TMEFF2,PRRX1,PACSIN1,MICAL2,VCAN,PUM1,ANKS1B,PLPPR5,LRRTM3,DNAJC6,PTHLH,PLPPR4,KCNK1,KCNK2,NAV2,KCNN3,KIF2A,SUSD4,SLC6A15,NUP214,RGS7" MicroRNA hsa-miR-15a*:mirSVR_highEffct hsa-miR-15a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.81E-18 3.15E-14 2.21E-17 2.02E-16 42 622 "ACLY,WLS,KLHL32,WAC,SCN3A,FGF14,MOBP,ANK2,NTNG1,NLGN1,MTR,TMEM108,FYN,CAB39,ARPP21,NCAM1,ADHFE1,DDR1,PTBP2,GPR88,TMEM257,RBFOX2,TPD52,CASC2,FAT3,CNRIP1,SNCAIP,CSF3R,PLPPR1,CADM2,ELMO1,KCNA1,KCNA2,SV2A,KCNK1,PCDH15,ABI1,DTNA,ARHGEF10L,ZNF248,RAVER2,EPB41L1" MicroRNA hsa-miR-1224-3p:mirSVR_highEffct hsa-miR-1224-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.95E-18 3.22E-14 2.26E-17 2.07E-16 37 476 "NDRG2,CDC7,LINC00461,ASIC4,PDZD4,CDC42BPA,ZNF365,MIER1,RUFY2,SLC8A3,SPHKAP,MYT1L,ARPP21,NDUFA5,GFAP,ADHFE1,CAMTA1,NODAL,PTBP2,CAMK2G,RBFOX2,PDE1A,TMPRSS5,PLEKHB1,HNRNPK,CADM1,CHD1L,PRKACB,LRRTM3,BDNF-AS,KCNK2,KCNN3,SLC17A6,ABI1,L1CAM,ABI2,EPB41" MicroRNA hsa-miR-218-5p:Non-Functional MTI Non-Functional MTI miRTarbase 6.31E-18 3.42E-14 2.39E-17 2.20E-16 48 816 "LGR4,ARID1A,SFPQ,CDC42BPA,ANK3,PKP4,DOCK10,APC,CCDC80,DGKZ,CLSTN1,MTR,ATM,EIF4G3,PALLD,KIF21B,SALL3,DCAF5,KIRREL3,GNAS,CAMTA1,GOLGB1,GPM6A,PSD3,TGFBR3,ZFP91,TPD52,TPM3,HMGB1,FADS2,VAV2,BTF3L4,VCAN,RBPJ,SDC3,SPIRE1,PTCH1,ITGAV,HP1BP3,BLOC1S6,KCNMA1,WIPF2,SUSD4,NUP214,RET,RFX5,PHC2,OLIG2" MicroRNA hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA_TOP PITA 6.34E-18 3.43E-14 2.40E-17 2.20E-16 32 345 "EYA1,SLITRK1,ADD3,SEMA6A,ACTL6B,FHL1,PPM1E,CACHD1,ARHGAP5,CAPRIN2,SNAP25,FAM168A,GLS,BTRC,WSCD1,SYT6,GRM3,CDH10,LGI1,TPM3,MED1,SNCAIP,TENM4,PMEPA1,CADM2,KCNA6,KCNMA1,DLG2,WIPF2,TMEM255A,SLC17A6,UEVLD" MicroRNA hsa-miR-1197:TargetScan hsa-miR-1197 TargetScan 6.55E-18 3.55E-14 2.48E-17 2.27E-16 24 171 "EXTL1,ADD3,CLSTN1,MADD,ARFGAP2,CCDC88A,PDE8B,ATP2B2,NMNAT2,LHFPL4,CACNA1A,GRIK3,OPCML,PTPN5,DAAM2,PAX6,REPS2,RBFOX2,KIAA1549L,CHD5,MAPK10,CA10,ABI2,EPB41L1" MicroRNA hsa-miR-501-3p:TargetScan hsa-miR-501-3p TargetScan 6.63E-18 3.59E-14 2.51E-17 2.30E-16 23 153 "RIMKLA,ADCY2,AMER2,APC,RPH3A,PDE8B,AHCYL1,ARPP21,CACNA1E,PTBP2,PSD3,GRIA1,OLR1,DCLK1,PDE3B,CADM1,OSBPL3,FAM131B,KIAA0408,CSDE1,KCNA1,KCND3,ABI2" MicroRNA hsa-miR-502-3p:TargetScan hsa-miR-502-3p TargetScan 6.63E-18 3.59E-14 2.51E-17 2.30E-16 23 153 "RIMKLA,ADCY2,AMER2,APC,RPH3A,PDE8B,AHCYL1,ARPP21,CACNA1E,PTBP2,PSD3,GRIA1,OLR1,DCLK1,PDE3B,CADM1,OSBPL3,FAM131B,KIAA0408,CSDE1,KCNA1,KCND3,ABI2" MicroRNA hsa-miR-613:mirSVR_highEffct hsa-miR-613:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.75E-18 3.65E-14 2.55E-17 2.34E-16 55 1062 "RABEPK,ACER3,ADGRV1,ADAR,ERMN,ASRGL1,ITSN1,API5,ZNF365,MIER1,DACH2,ASPH,SORCS3,SNAP25,USP33,SOX5,ILDR2,GAD2,NPAS3,FGF17,NEUROD1,GLS,WWC1,KLHL4,ANO4,TCF7L2,OLR1,CDC42,LGI1,TPM3,TPM4,MAGI1,PIRT,HNRNPK,GDAP1L1,BEST1,MED1,RNF14,RBPJ,PRKACB,KIAA0513,ELMO1,OCIAD1,SMG7,PLPPR4,KCNK2,KIF2A,FAM66C,PARP11,SLC6A15,CRTAC1,RGS7,SYT15,SLC4A10,BSCL2" MicroRNA hsa-miR-33b:PITA hsa-miR-33b:PITA_TOP PITA 6.94E-18 3.76E-14 2.62E-17 2.40E-16 27 231 "SLC25A25,GPR158,UNC79,CDC42BPA,ANK3,SLITRK3,B3GALT2,ENKUR,SALL3,NAP1L2,CAMK2G,GPR88,TNS1,LGI1,TPM3,KIAA1549L,PACSIN1,PPP3CB,DPYSL5,KCNA4,KCNMA1,WIPF2,SLC17A6,GOPC,SLC6A15,SLC4A10,EN2" MicroRNA hsa-miR-376c:PITA hsa-miR-376c:PITA_TOP PITA 7.05E-18 3.82E-14 2.66E-17 2.44E-16 30 298 "FAM43B,SCN3A,AMPH,ANK1,CNIH2,SLC1A2,DACH2,SPHKAP,RCOR3,SNCB,NCAM1,ERBIN,ADGRL3,GPM6A,CACNB2,PTBP2,GRIA2,GRM3,OPCML,HNRNPK,PKN2,TOX,RIMS3,LRP8,PTPRD,DLG2,TMEM255A,SFXN5,RAVER2,EN2" MicroRNA hsa-miR-3171:mirSVR_highEffct hsa-miR-3171:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.13E-18 3.86E-14 2.69E-17 2.47E-16 58 1174 "ACER3,SYT9,WLS,CSMD3,SCN3A,LINC00461,BCAR3,ERICH3,ITSN1,PKP4,APC,MAGI3,ST3GAL3,SLC2A5,MSR1,SLIT1,ASPH,SMARCE1,PHYHIPL,MEGF11,SOX5,KIF21B,ARPP21,SALL3,TTLL9,LMO3,NDUFA5,DCAF5,RND1,PCDH11X,GNAS,CACNB2,NUDT21,GRIA2,DAAM2,PDE3B,SCRG1,NRXN1,A2ML1,PRRX1,CP,CRLS1,VCAN,CTNND2,SYNC,PTHLH,ITIH2,HP1BP3,LRP8,KCNA4,PLPPR4,DLG3,SLC25A48,SUSD4,DTNA,SLC6A15,VWA5A,SLC4A10" MicroRNA hsa-miR-615-5p:mirSVR_lowEffct hsa-miR-615-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.31E-18 3.96E-14 2.75E-17 2.53E-16 53 992 "ACHE,APC2,MEG3,RXRG,CDC7,PNMA8B,ADORA1,CHST15,LRRTM4,LRRC7,SEMA6A,FGR,PDZD4,ANK1,ANK3,PPFIA1,ITSN1,BCAS1,ZNF365,MSRA,NAXD,RAP1GAP2,RCOR2,ARHGEF7,PCDH11X,ASTN2,ZEB1,NUCB1,ATP13A2,LINC00839,TMEM25,ARHGAP22,NLGN3,FADS2,CELF5,PPP2R5C,RGS6,NRSN1,PUM1,NOS1AP,PTCH1,ITGAV,PMEPA1,PRDM2,KCNH1,SV2A,SRGAP3,PYGM,DNAH9,RAB5B,SLC17A6,L1CAM,EPB41L2" MicroRNA hsa-let-7i:mirSVR_highEffct hsa-let-7i:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.42E-18 4.02E-14 2.79E-17 2.56E-16 47 786 "LGR4,MDM4,CLIP1,KLHL32,RUFY2,GABBR1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,GNAS,GPM6B,ACSL6,CACNB2,ADAMTS8,GPR88,CRB1,TGFBR3,AIFM1,HERC2P3,SERPINE2,SLC25A27,BEST1,PRRX1,MFSD4A,MICAL2,OSBPL3,PLPP4,IGSF1,MASP1,SYNC,BDNF-AS,CADM2,PRDM2,PTPRO,KCNJ11,KCNK1,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-628-5p:mirSVR_highEffct hsa-miR-628-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.73E-18 4.19E-14 2.91E-17 2.67E-16 49 854 "CNTNAP3,MEG3,MDM4,SLITRK1,SLC44A5,SCN3A,KIAA1109,FGF1,BCAR3,MOG,ANK3,NTNG1,SLCO1A2,RCOR3,PHYHIPL,USP33,CAB39,RGL1,SLCO1C1,CASTOR3,ZNF638,SYT4,KAZN,ANO4,ACSL6,CACNB2,PTBP2,CAMK2G,GRIA4,GPR88,GUCY1A2,CDH10,TPM4,FNDC5,CHD1L,MED1,KCNT2,VCAN,KIAA1755,PLD5,CTNND1,ANKS1B,HP1BP3,MAGI2,HS3ST4,PID1,SLC6A15,RFX4,RCAN2" MicroRNA hsa-miR-635:mirSVR_highEffct hsa-miR-635:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.74E-18 4.19E-14 2.91E-17 2.67E-16 43 658 "RBM10,LDLRAD3,MDM4,KLHL32,RTN1,GALNT13,SLC30A10,MOBP,FOXG1,PKP4,SHTN1,SLC8A3,MTR,MEGF11,TTLL9,DCAF5,ABCC8,DCLK2,ANO4,PCDHGA3,GRIA4,OLR1,LINC00839,PAH,PCDH9,LGI1,PRMT8,MS4A7,DUSP26,GDAP1L1,TJP2,PMP2,MED1,PROX1,KIAA0513,PSMD13,LRP8,CEP170,PTPRE,DPP6,JMJD1C,SIDT2,EPB41L2" MicroRNA hsa-miR-1287:mirSVR_highEffct hsa-miR-1287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.76E-18 4.20E-14 2.92E-17 2.68E-16 46 754 "SYT9,LGR4,AMER2,SLC44A5,TESK2,UNC79,ELMOD1,ERICH3,SGIP1,CAPRIN2,SORCS3,ATM,PALLD,DKK3,SOX5,ARPP21,KIF1B,C11orf87,DDHD2,PSRC1,GPM6A,LRIT2,TCF12,GRIA4,INA,P2RX7,MAEL,BEST3,JAM2,DUSP26,KCNT2,FEZ1,PLD5,IGSF1,KIAA0408,MASP1,PTAFR,ELMO1,OCIAD1,PID1,DBX2,DTNA,PAK5,ZYG11B,RFX5,RCAN2" MicroRNA hsa-miR-382:PITA hsa-miR-382:PITA_TOP PITA 7.82E-18 4.23E-14 2.93E-17 2.69E-16 29 276 "LGR4,NDRG2,GPR158,SCN3A,PKP4,GPAM,MIER1,SORCS3,EIF4G3,WDTC1,SOX5,NCAM1,SMOC1,SEPT3,NFIA,SYT4,CAMTA1,KLHL4,ANO4,OPCML,PCDH9,PDE1C,NEGR1,UBTF,BEST1,TOX,SYNC,SLC17A6,EN2" MicroRNA hsa-miR-1253:PITA hsa-miR-1253:PITA_TOP PITA 7.82E-18 4.23E-14 2.93E-17 2.69E-16 29 276 "ACLY,RTN1,DSCAML1,SORCS1,LRRC7,PPM1E,NLGN1,WDTC1,AHCYL1,JPH4,NEK6,CPLX2,NPAS3,VAMP1,CAMTA1,ADGRL3,CACNA1E,EML4,RBFOX2,PDE1C,CADM1,ANLN,MED1,PLD5,SYNC,DLG2,NKAIN1,SIDT2,EPB41L1" MicroRNA hsa-miR-196b:mirSVR_highEffct hsa-miR-196b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.95E-18 4.30E-14 2.98E-17 2.73E-16 45 722 "SYT9,FAM43B,RTKN,WAC,SORCS1,ERMN,FHL1,ERICH3,MIER1,SLC14A1,ATP1A2,PALLD,DNER,CAMTA1,KLHL4,ANO4,GPM6B,ACSL6,CACNA1E,CACNB2,ZEB1,PTBP2,GRIA2,OPCML,TMEM25,PDE3B,TMEFF2,A2ML1,BEST1,CHD1L,PPP3CB,ATRNL1,DZIP3,CTNND1,ANKS1B,ZNF385B,CA10,HP1BP3,SMG7,KCNJ10,FAM13C,ZNF248,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-1264:PITA hsa-miR-1264:PITA_TOP PITA 8.25E-18 4.47E-14 3.09E-17 2.84E-16 36 453 "ARID1A,GPR158,TESK2,LRRC7,SEMA6A,ELMOD1,APBA2,MAGI3,NLGN1,AQP4,MYT1L,NFASC,GLS,CAMSAP2,TCF12,PSD3,GRIA2,OPCML,ADGRG1,NRXN1,PPP3CB,KCNT2,ATRNL1,CHD5,PLPP4,PLD5,TOX,ITGAV,KCNA1,PTPRO,PTPRZ1,RABGAP1L,TTLL7,RBM12,GPR61,ARHGAP12" MicroRNA hsa-miR-4279:mirSVR_highEffct hsa-miR-4279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.48E-18 4.59E-14 3.18E-17 2.91E-16 52 960 "ZFYVE27,FAM43B,ARID1A,ADCY2,SCN3A,FGF1,SELL,PPFIA1,ITSN1,SH3GL2,MSR1,MTR,SMARCE1,RCOR3,MEGF11,ARPP21,NPAS3,C11orf87,CLASP2,GPR162,ASTN2,UNC5D,MMD2,ANO4,CACNA1E,GRIA2,LINC00839,P2RX7,TNR,PRMT8,NMT2,A2ML1,BTF3L4,CHD1L,MED1,CSF3R,FEZ1,PLD5,TOX,WBP1L,DNAJC6,CA10,PRDM2,STMN4,SMG7,KCNK1,KCNMA1,KCNN3,RFX4,CBLN2,SLC4A10,RCAN2" MicroRNA hsa-miR-640:mirSVR_highEffct hsa-miR-640:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.59E-18 4.65E-14 3.21E-17 2.95E-16 46 756 "ATAT1,WLS,ITSN1,ANXA7,SH3GL2,SORBS1,USP16,ZNF365,CAPRIN2,SCN3B,NFASC,NCAM1,NELL1,GANAB,CNDP1,ANO4,WSCD1,GPM6B,NUDT21,GRID1,GRIK2,ZFP91,C1orf94,PDYN,ZMYND8,ANO5,HERC2P3,SLC25A27,PRRX1,ACBD5,PKN2,BDNF-AS,CADM2,CEP170,MAGI2,ZC3H11A,PTPRD,RABGAP1L,ARNT2,PCDH15,KCNMA1,DTNA,JMJD1C,RPRD1A,VWA5A,RASGRP2" MicroRNA "TTGCACT,MIR-130A:MSigDB" "TTGCACT,MIR-130A:MSigDB" MSigDB 8.68E-18 4.70E-14 3.24E-17 2.97E-16 33 374 "PRR5L,RTN1,ADCY2,TESK2,SYBU,MIER1,CCDC88A,SHANK2,SNAP25,ATP2B2,USP33,SOX5,SPART,SMOC1,ERBIN,NEUROD1,CAMTA1,ZFP91,PFKFB3,ZFYVE9,BTF3L4,ACBD5,POU3F2,PSD,PMEPA1,LRP8,CEP170,SNX27,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12" MicroRNA "TTGCACT,MIR-130B:MSigDB" "TTGCACT,MIR-130B:MSigDB" MSigDB 8.68E-18 4.70E-14 3.24E-17 2.97E-16 33 374 "PRR5L,RTN1,ADCY2,TESK2,SYBU,MIER1,CCDC88A,SHANK2,SNAP25,ATP2B2,USP33,SOX5,SPART,SMOC1,ERBIN,NEUROD1,CAMTA1,ZFP91,PFKFB3,ZFYVE9,BTF3L4,ACBD5,POU3F2,PSD,PMEPA1,LRP8,CEP170,SNX27,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12" MicroRNA "TTGCACT,MIR-301:MSigDB" "TTGCACT,MIR-301:MSigDB" MSigDB 8.68E-18 4.70E-14 3.24E-17 2.97E-16 33 374 "PRR5L,RTN1,ADCY2,TESK2,SYBU,MIER1,CCDC88A,SHANK2,SNAP25,ATP2B2,USP33,SOX5,SPART,SMOC1,ERBIN,NEUROD1,CAMTA1,ZFP91,PFKFB3,ZFYVE9,BTF3L4,ACBD5,POU3F2,PSD,PMEPA1,LRP8,CEP170,SNX27,RAB5B,DNM2,ATG16L1,ST8SIA3,ARHGAP12" MicroRNA hsa-miR-1285:mirSVR_highEffct hsa-miR-1285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.78E-18 4.76E-14 3.28E-17 3.01E-16 50 891 "SDE2,SRARP,ATAT1,RTKN,KCNIP2,ADARB2,ADCY2,SORCS1,NLGN4X,SNX32,FGF1,MOG,ITSN1,SH3GL2,NTNG1,SLITRK3,ARFGAP2,SPHKAP,CAPRIN2,MYBPC1,B4GALNT1,LMO3,COLGALT2,GFAP,SEPT3,GPR19,TCF12,PTBP2,INA,DAAM2,PRMT8,GPR37L1,KIAA1549L,NRXN1,FAT3,NXPH1,SF1,PPP3CB,OSBPL3,DZIP3,IGSF1,EDRF1,ECE2,LRRTM3,MAGI2,ZC3H11A,KCNK2,C12orf4,RET,SLC4A10" MicroRNA hsa-miR-1207-5p:mirSVR_highEffct hsa-miR-1207-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.03E-18 4.89E-14 3.37E-17 3.09E-16 47 790 "ZFYVE27,SORCS1,SNX32,TESK2,FOXM1,SGIP1,ITSN1,APC,ZCCHC17,SYBU,SLC1A7,SLC6A9,B4GALNT1,ADAM15,NELL1,ADHFE1,OS9,CDK5R2,GOLGB1,AZIN2,DDR2,OLR1,CRB1,INA,SEZ6L,LGI1,ZMYND8,CHRM1,PLEKHB1,DLGAP3,CADM1,ZFYVE9,CCSER2,FLRT1,COL9A2,ACBD5,MED1,PNKD,SNCAIP,NRSN1,MASP1,SV2A,DNM2,SLC25A18,RAP1GAP,CACNG7,VWA5A" MicroRNA hsa-miR-568:PITA hsa-miR-568:PITA_TOP PITA 9.94E-18 5.38E-14 3.70E-17 3.40E-16 38 512 "CSMD2,GPR158,LRRC7,GAS7,SORBS1,NLGN1,ARHGAP5,ASCL1,SOX1,ZCCHC24,NEUROD1,SYT4,CAMSAP2,GPM6A,TCF12,EML4,TJP1,MED1,PPP3CB,ATRNL1,PHACTR3,PRKAB2,PUM1,BRINP3,PMEPA1,CADM2,CNIH3,LRP8,KCNA4,DLG2,DLG3,RAB5B,TMEM255A,SLC17A6,ABI1,GOPC,FAM13C,SLC6A15" MicroRNA hsa-miR-3191:mirSVR_lowEffct hsa-miR-3191:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-17 5.72E-14 3.93E-17 3.61E-16 39 542 "DPF1,CDHR1,AMER2,FCGR1B,SCN3A,UNC79,MOBP,FOXM1,PKP4,BCAN,API5,SFMBT2,PDE8B,FYN,FXYD6,NPAS3,C11orf87,KAZN,WWC1,PRLHR,TCF7L2,NRGN,BRSK2,CYB561A3,ZDHHC22,TNS1,PFKFB3,FEZ1,PRKCZ,PTPRE,KCNJ9,KCNMA1,DLG2,SLC25A48,DNM2,RAP1GAP,VANGL2,RNF220,GPR61" MicroRNA hsa-miR-935:mirSVR_highEffct hsa-miR-935:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-17 5.97E-14 4.10E-17 3.76E-16 50 896 "PRR5L,ACLY,RTN3,ADGRV1,GALNT13,ADD3,FGF1,LRRC7,FHL1,APC,NTNG1,ZNF365,LRRC55,CCDC88A,CADPS,MYT1L,CAB39,NAP1L2,RGL1,ADHFE1,PCDH11X,ZNF638,UNC5D,ANO4,GPM6A,ACSL6,GPR88,GRM3,TMEM257,PCDH9,LGI1,HMGB1,A2ML1,POU3F2,FEZ2,DZIP3,PRKCZ,NRSN1,PTAFR,ZC3H11A,KCNC1,ARNT2,PEX5,KCNQ2,DLG2,GOPC,ABCC9,INSYN2,SSPN,RAVER2" MicroRNA hsa-miR-1226:mirSVR_highEffct hsa-miR-1226:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-17 6.14E-14 4.22E-17 3.87E-16 41 603 "FCGR1A,TESK2,MOG,SFPQ,PPFIA1,ITSN1,PKP4,SH3GL2,NTNG1,ST3GAL3,ARFGAP2,CGREF1,NAXD,PALLD,SOX5,SALL3,TTLL9,ADAM15,NPAS3,NCAM1,LMO3,NDUFA5,ADHFE1,NODAL,EML4,CAMK2G,GRIA2,GRIA4,CCKBR,TMEM257,ACOT7,MFSD4A,MED1,PRKCG,PRKCZ,SYNC,PTPRE,KCNK2,ATG16L1,ABI1,ELAVL3" MicroRNA hsa-miR-4301:mirSVR_lowEffct hsa-miR-4301:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-17 6.22E-14 4.27E-17 3.92E-16 52 967 "WLS,FCGR1A,TOMM40L,MOBP,SOX6,ITSN1,GPAM,BCAS1,USP16,SLC2A5,LRRC55,CSPG5,NAXD,DDX25,SMARCE1,ATP1A3,CPLX2,NFASC,NCAM1,NDUFA5,SMOC1,GLS,ADGRL3,CACNB2,GRIA4,GRID1,MAEL,RBFOX2,PDYN,TJP2,CHD1L,PPP3CB,DOCK7,TOMM20,PTCH1,COPS7A,PTPRO,KCND3,DLG3,CAB39L,HS3ST4,PID1,GNE,L1CAM,ABCC9,ZNF248,SYT15,SEC61A2,EFNA3,SH3GLB1,FGFBP3,ELAVL4" MicroRNA hsa-miR-518f*:mirSVR_highEffct hsa-miR-518f*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-17 6.29E-14 4.30E-17 3.95E-16 46 762 "ADGRV1,EYA1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,BCAS1,STK32C,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,GFAP,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SPATA6,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-526a:mirSVR_highEffct hsa-miR-526a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-17 6.29E-14 4.30E-17 3.95E-16 46 762 "ADGRV1,EYA1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,BCAS1,STK32C,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,GFAP,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SPATA6,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-518d-5p:mirSVR_highEffct hsa-miR-518d-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-17 6.29E-14 4.30E-17 3.95E-16 46 762 "ADGRV1,EYA1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,BCAS1,STK32C,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,GFAP,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SPATA6,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-520c-5p:mirSVR_highEffct hsa-miR-520c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-17 6.29E-14 4.30E-17 3.95E-16 46 762 "ADGRV1,EYA1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,BCAS1,STK32C,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,GFAP,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SPATA6,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-let-7f:mirSVR_highEffct hsa-let-7f:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.18E-17 6.38E-14 4.36E-17 4.00E-16 48 829 "LGR4,MDM4,KLHL32,ERMN,FGR,MOBP,SESN3,GABBR1,CAB39,KIF1B,DNER,FXYD6,CLASP2,ADHFE1,GANAB,ACSL6,CACNB2,TCF12,ADAMTS8,CRB1,TGFBR3,AIFM1,SERPINE2,PMP2,SLC25A27,PRRX1,SPATA6,MFSD4A,MICAL2,OSBPL3,IGSF1,MASP1,SYNC,BDNF-AS,PRDM2,PTPRO,KCNJ11,KCNK1,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,DTNA,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-3152:mirSVR_highEffct hsa-miR-3152:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-17 6.50E-14 4.45E-17 4.08E-16 43 666 "TTYH1,SYT9,ATAT1,AMER2,LRRTM4,FHL1,ANK2,ANK3,ASPH,SORCS3,B3GAT1,SNAP25,ATP1A2,TNIK,KIF1B,FXYD6,COLGALT2,CAMTA1,BRSK2,CD81,CHGA,HNRNPK,KIAA1549L,CCSER2,PPP2R5C,TENM4,PHACTR3,RBPJ,USP54,IGSF1,GON4L,PLPPR5,TUBB2B,LRRTM3,HP1BP3,PTPRD,PTPRE,KCNJ10,DTNA,ZYG11B,SFXN5,VWA5A,OLIG2" MicroRNA hsa-miR-3174:mirSVR_highEffct hsa-miR-3174:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-17 6.78E-14 4.63E-17 4.25E-16 52 969 "RTN3,ATAT1,KLHL32,GALNT13,ERMN,FGF1,ERICH3,APC,MAGI3,SLITRK3,SLC1A6,YPEL4,ASPH,ENKUR,GART,ADGRB2,NASP,CLASP2,NDUFA5,ERBIN,LILRA1,NRGN,PTBP2,GRIA1,TMEM9,MAEL,PADI2,ZNF384,PDE4B,BEST3,HMGB1,CASC2,P2RY12,NSD2,FEZ2,USP54,WBP1L,ANKS1B,SYNC,PSMD13,CA10,BDNF-AS,PTHLH,RABGAP1L,KCNJ10,PCDH15,SUSD4,ABCC9,ZYG11B,RFX4,EPB41L1,EPB41L2" MicroRNA hsa-miR-3127:mirSVR_highEffct hsa-miR-3127:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-17 7.22E-14 4.93E-17 4.52E-16 45 732 "ACER3,RXRG,WAC,AMER2,TOMM40L,SNX32,TESK2,AGT,DGKZ,RUFY2,MSR1,CGREF1,SLN,RCOR3,ATM,PHYHIPL,MEGF11,USP33,WDTC1,NAP1L2,BCL2L2,GANAB,ZNF638,DDHD2,ADGRL3,GOLGB1,CACNA1E,PRLHR,ZEB1,AKNA,CHI3L2,PRRX1,CP,SNCAIP,CSF3R,NCAN,PKN2,PLPPR1,ZC3H11A,OLFM3,SV2A,KCNMA1,FAM13C,PHC2,RLBP1" MicroRNA hsa-let-7c:mirSVR_highEffct hsa-let-7c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.34E-17 7.23E-14 4.93E-17 4.52E-16 47 798 "LGR4,ARID1A,RTKN,MDM4,KLHL32,ERMN,SESN3,PAAF1,GABBR1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,GNAS,ACSL6,CACNB2,ADAMTS8,GPR88,CRB1,TGFBR3,AIFM1,SERPINE2,SLC25A27,BEST1,PRRX1,MFSD4A,MICAL2,OSBPL3,PLPP4,IGSF1,MASP1,SYNC,BDNF-AS,PRDM2,PTPRO,KCNJ11,KCNK1,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-1229:mirSVR_highEffct hsa-miR-1229:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-17 7.38E-14 5.03E-17 4.62E-16 42 637 "EXTL1,GALNT13,KIAA1109,SLC30A10,MOBP,APC,ZCCHC17,ST3GAL3,ZNF365,SLC2A5,LRRC55,ASCL1,SPHKAP,NAXD,SMARCE1,SNAP25,SOX5,ZCCHC24,KIF1B,NELL1,GNAS,TMEM136,DDR1,PRLHR,ZEB1,RFFL,CRB1,TGFBR3,ZDHHC22,RBFOX2,CASC2,DUSP26,CADM1,KIAA1549L,TJP2,CELF5,NXPH1,PRKCG,PRKCZ,PLPPR1,PTPRD,WIPF2" MicroRNA hsa-miR-519b-5p:mirSVR_highEffct hsa-miR-519b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-518e*:mirSVR_highEffct hsa-miR-518e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-519c-5p:mirSVR_highEffct hsa-miR-519c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-519a*:mirSVR_highEffct hsa-miR-519a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-522*:mirSVR_highEffct hsa-miR-522*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-523*:mirSVR_highEffct hsa-miR-523*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-17 8.41E-14 5.71E-17 5.24E-16 45 735 "ADGRV1,KCNIP2,KLHL32,SORCS1,SCN3A,SEMA6A,MOBP,ANK2,ANK3,BCAS1,MSR1,SLC14A1,SCG3,DLL3,NRG3,JPH4,IDI2-AS1,NPAS3,SPART,LMO3,ZNF638,DDHD2,INA,TPM3,ZNF384,PDE3B,PIRT,NRXN1,NRXN2,SNCAIP,PRKACB,BRINP3,PLPPR1,ELMO1,PRDM2,HP1BP3,OLFM3,OCIAD1,KCNJ11,ATN1,RFX4,TTLL7,SEC61A2,SLC4A10,EPB41" MicroRNA hsa-miR-24-2*:mirSVR_lowEffct hsa-miR-24-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-17 8.48E-14 5.75E-17 5.28E-16 46 768 "MDM4,SORCS1,BCAR3,APC,CCDC80,ARHGAP5,SLC8A3,CCDC88A,SLCO1A2,ASTN1,WDTC1,NFASC,DCAF5,NEUROD1,PCDH11X,MMD2,GPM6A,GPM6B,CACNA1E,PTBP2,CAMK2A,NUMA1,TMEM25,CDH10,TPM3,PDE3B,PRMT8,PRRX1,SNCAIP,PRKAB2,DZIP3,PKN2,FGFR1OP2,ZBTB16,OCIAD1,PTPRE,KCNJ10,KCNMA1,DNAH9,SLC17A6,ABI1,ATN1,ZYG11B,RFX4,VWA5A,RCAN2" MicroRNA hsa-miR-627:mirSVR_highEffct hsa-miR-627:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-17 9.35E-14 6.34E-17 5.82E-16 50 906 "SRARP,DSCAML1,SLITRK1,GALNT13,LINC00461,ITSN1,APBA2,ZCCHC17,CACHD1,API5,SMARCE1,SNAP25,JPH4,B4GALNT1,GART,NDUFA5,NELL1,SEPT3,POPDC3,DCLK2,LRIT2,MFSD2A,AIFM1,PAH,PADI2,TPM3,ZMYND8,TMPRSS5,CHGA,CASC2,HNRNPK,GDAP1L1,BTF3L4,CRLS1,PPP3CB,NCAN,CTNND1,PTHLH,KCNA1,PTPRE,CCDC3,DLG2,FAM13C,JMJD1C,FAM135B,INSYN2,RBM12,ROM1,EN2,EPB41" MicroRNA hsa-miR-664*:mirSVR_highEffct hsa-miR-664*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-17 1.02E-13 6.89E-17 6.32E-16 51 943 "PRR5L,TMEM74,LGR4,ERMN,ADORA3,LRRC7,FGF14,ERICH3,SH3GL2,APC,DGKZ,NLGN1,ZNF365,SLC14A1,RCOR3,TMEM108,KIF21B,ZSWIM8,NCAM1,NELL1,ACSBG1,GLS,PCDH11X,LUZP2,DDHD2,ANO4,SYT6,AKNA,GRIA1,GRIK2,GPR88,TGFBR3,MAGI1,PDE3B,HMGB1,MS4A7,CADM1,CP,MICAL2,PRKACB,PUM1,NOS1AP,JAKMIP2,SLC25A48,PLEKHB2,RASGRF1,SLC6A15,ZYG11B,SSPN,SLC4A10,TMEM100" MicroRNA hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA_TOP PITA 1.91E-17 1.03E-13 7.00E-17 6.42E-16 33 384 "SORCS1,NLGN4X,ANXA7,SESN3,SLITRK3,SHTN1,PALLD,MYT1L,NEK6,LMO3,ERBIN,PCDH11X,CAMTA1,ADGRL3,PTBP2,ZFP91,PCDH8,MAGI1,PDE4B,HNRNPK,TMEFF2,BEST1,MED1,PKN2,PUM1,DNAJC6,SNX27,SLC17A6,ABI1,FAM13C,EFNA3,ABI2,SEZ6" MicroRNA hsa-miR-146b-5p:mirSVR_highEffct hsa-miR-146b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.98E-17 1.07E-13 7.26E-17 6.66E-16 54 1052 "SYT9,LDLRAD3,KIAA1109,LRRC7,FHL1,AMPH,ITSN1,SH3GL2,SESN3,CCDC88A,DACH2,CSPG5,CAPRIN2,PHYHIPL,USP33,B3GALT2,CLASP2,COLGALT2,DCAF5,DDHD2,CAMSAP2,ADGRL3,KLHL4,EML4,GRID1,USP2,MFSD2A,TJP1,CELF3,CDH10,NLGN3,DNAJC12,SLC25A27,BTF3L4,POU3F2,MED1,USP54,IGSF1,MAPK10,PUM1,TOX,PLPPR5,ZNF385B,LRRTM3,CADM2,HP1BP3,PTPRE,SRGAP3,KCNK2,PID1,DTNA,SLC6A15,INSYN2,TMEM100" MicroRNA hsa-miR-3116:mirSVR_highEffct hsa-miR-3116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-17 1.11E-13 7.53E-17 6.91E-16 44 708 "RABEPK,PRR5L,KCNIP2,CLIP1,SORCS1,GRAMD1B,SOX6,PPFIA1,APC,ST3GAL3,MIER1,ARHGAP5,CAPRIN2,SORCS3,B3GAT1,SON,ADHFE1,SLCO1C1,CAMTA1,CACNB2,CYB561A3,TJP1,PDE3B,FNDC5,BEST3,ANO5,MS4A7,CPT1C,OPALIN,MEAF6,FAT3,MFSD4A,SF1,PPP3CB,RGS6,VCAN,USP54,PTAFR,SRGAP3,RAD52,DSCAM,RPRD1A,ABI2,UEVLD" MicroRNA hsa-miR-342-3p:mirSVR_highEffct hsa-miR-342-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.17E-17 1.17E-13 7.92E-17 7.27E-16 44 709 "WLS,FOXG1,SOX6,AQP4,MT3,SPHKAP,ASTN1,SNAP25,DKK3,ILDR2,EMC1,NPAS3,GLS,VAMP1,SYT4,NKX2-2,TBX15,GPM6A,ZEB1,TCF12,SYT6,PDE1A,CIART,CAMKV,NOMO2,ANLN,CPT1C,TJP2,FMN2,CTNND1,CTNND2,LRP8,OCIAD1,PLPPR4,NTM,AK5,KIF2A,RAD52,GOPC,DSCAM,SLC6A15,ZYG11B,TTLL7,SEC61A2" MicroRNA hsa-miR-642:mirSVR_highEffct hsa-miR-642:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-17 1.18E-13 7.97E-17 7.31E-16 52 982 "RTN3,CSMD3,FCGR1A,DRAXIN,KIAA1109,SEMA6C,DGKZ,SORBS1,ST3GAL3,BCAS1,ZNF365,MSR1,ASPH,SMARCE1,ATM,SOX5,ERBIN,RGL1,RND1,CASTOR3,PCDH11X,UNC5D,MMD2,CACNA1E,LILRA1,CRB1,TMEM25,INA,TNS1,PCDH9,CDH8,NLGN3,NEGR1,CCSER2,TJP2,MFSD4A,CP,SNCAIP,DOCK7,BRINP3,SYTL2,LRRTM3,JAKMIP2,KCNA4,WIPF2,FAM13C,FAM135B,INSYN2,PIANP,RPRD1A,VWA5A,EPB41" MicroRNA hsa-miR-1294:mirSVR_highEffct hsa-miR-1294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.21E-17 1.20E-13 8.08E-17 7.41E-16 46 775 "ADGRV1,ATAT1,ARID1A,KLHL32,FCGR1A,UNC79,MOBP,TRIM46,MAGI3,MSR1,SCMH1,ASTN1,RCOR3,TTLL9,KIF1B,GART,ARHGEF7,SYT4,NPPA,ADAMTS8,CCKBR,CDH10,RBFOX2,LGI1,PRMT8,ACOT7,HERC2P3,NLGN3,FTO,PMP2,MEAF6,PRRX1,SNCAIP,DZIP3,IGSF1,KIAA0513,PLPPR5,CA10,PRDM2,KCNC1,DTNA,ZYG11B,ARHGEF10L,VANGL2,RAVER2,ROM1" MicroRNA hsa-miR-8485:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-17 1.21E-13 8.16E-17 7.48E-16 49 877 "ATAT1,CSMD2,ADCYAP1R1,PNMA8B,CHST15,GOLGA7B,MOBP,PDZD4,SGIP1,ANK3,JAKMIP3,CADPS,ATP1A3,WDTC1,CADM3,LHFPL4,FXYD6,NDUFA5,INKA2,SEPT3,AJAP1,RHBDL3,ASTN2,TCF7L2,TCF12,EML4,GRID1,GRIK3,ZDHHC22,KCNK10,DAAM2,PADI2,PRMT8,UBTF,FAT3,SF1,CRLS1,NOS1AP,KIAA0408,RIMS3,PTCH1,LRP8,MED24,KCNA4,KCNJ10,KCNK1,DTNA,FGFBP3,ARHGAP12" MicroRNA hsa-miR-617:mirSVR_highEffct hsa-miR-617:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-17 1.29E-13 8.66E-17 7.95E-16 42 647 "EPS8,ACTN2,ADGRV1,ATAT1,AMER2,CHST15,FGF1,FOXG1,C1orf61,PPFIA1,ITSN1,SORBS1,SYBU,SHTN1,SLC14A1,SPHKAP,ASPH,SLN,SOX1,SOX5,SLCO1C1,KAZN,DDHD2,ANO4,ZEB1,VWCE,ZFP91,PCDH9,HNRNPK,MEAF6,BTF3L4,GON4L,SYNC,CA10,PCDH15,FAM66C,DTNA,ZYG11B,RFX5,TTLL7,ARHGAP12,SEZ6" MicroRNA hsa-miR-621:mirSVR_lowEffct hsa-miR-621:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-17 1.32E-13 8.89E-17 8.16E-16 46 777 "PRR5L,MAP6,DUSP27,ACTN2,MRVI1,KLHL32,NLGN4X,MOBP,PPFIA1,GPAM,SLITRK3,ST3GAL3,SLC14A1,DACH2,ASPH,DKK3,SCN3B,C11orf87,ALDH1L1,ACSBG1,PCDH11X,TCF12,AZIN2,EML4,TMEM151B,BRSK2,CRB1,TMEM25,LEFTY2,USP2,PADI2,NRXN1,PLXNB3,PTPA,KIAA1755,GON4L,PLPPR5,PTPRD,PTPRE,PTPRZ1,DPP6,RALGDS,ATN1,TTLL7,SEC61A2,OLIG2" MicroRNA hsa-miR-183:PITA hsa-miR-183:PITA_TOP PITA 2.49E-17 1.35E-13 9.06E-17 8.31E-16 28 265 "MRVI1,CLIP1,SLITRK1,SOX6,ANK1,PKP4,PPM1E,GPAM,SLITRK3,ARFGAP2,NCAM1,LMO3,ERBIN,NCDN,GNG4,TCF7L2,TCF12,EML4,GRIK2,KCNK10,REPS2,TPM3,MED1,PPP2R5C,SIRPA,KCNK2,KIF2A,ABI2" MicroRNA hsa-miR-1231:mirSVR_highEffct hsa-miR-1231:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-17 1.37E-13 9.22E-17 8.45E-16 41 617 "RPL38,TMEM74,MBP,ATAT1,ERMN,FGF14,AMPH,PPM1E,NTNG1,GPAM,ZCCHC17,AQP4,RUFY2,MTR,JPH4,ARPP21,NCAM1,COLGALT2,GLS,BTRC,ZEB1,PTBP2,GPR88,CCKBR,INA,TMEM257,CDH8,LGI1,PDYN,HPSE2,PACSIN1,IGSF1,SYNC,OLFM3,KCNMA1,DNAH9,DPP6,SUSD4,GOPC,ZYG11B,RFX4" MicroRNA hsa-miR-132:mirSVR_highEffct hsa-miR-132:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.57E-17 1.39E-13 9.36E-17 8.58E-16 53 1022 "PRR5L,CNTNAP3,LGR4,ARID1A,RTKN,KCNIP2,SCN3A,LRRTM4,SEMA6A,NTNG1,MAGI3,BCAN,API5,SHTN1,MIER1,ARFGAP2,PDE8B,CAPRIN2,RCOR3,DKK3,SON,SOX5,ILDR2,IDI2-AS1,C11orf87,NDUFA5,ERBIN,SEMA4A,CAMSAP2,ADGRL3,TMEM136,PTBP2,GRIA2,GPR88,GRM3,RBFOX2,JAM2,SERPINE2,CCSER2,ETNPPL,CRLS1,PPP2R5C,LRRTM3,CSDE1,PTPRD,SV2A,KCNK2,PCDH15,GNE,FAM13C,RTN4,RFX4,EPB41" MicroRNA hsa-miR-616:mirSVR_highEffct hsa-miR-616:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.61E-17 1.42E-13 9.50E-17 8.72E-16 47 812 "SYT9,MDM4,CDC7,FGF1,BBOX1,ANK2,ITSN1,NTNG1,API5,ZNF365,SLC2A5,BCO1,CAB39,ILDR2,KIF1B,NFASC,NEUROD1,ZNF638,KLHL4,GPM6A,CACNB2,VSTM2A,GRIA2,GRIK2,GPR88,CCKBR,TJP1,MAEL,PCDH9,LGI1,TMPRSS5,CHRM1,CASC2,A2ML1,NRSN1,MAPK10,FAM131B,PROX1,BRINP3,CEP170,PTPRE,FAM66C,RAP1GAP,DTNA,SLC6A15,YY1AP1,EPB41L2" MicroRNA hsa-miR-483-5p:mirSVR_lowEffct hsa-miR-483-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.73E-17 1.48E-13 9.94E-17 9.12E-16 48 847 "TTYH1,ACHE,KCNIP2,NDRG2,CLIP1,WAC,CHST15,ELMOD1,SEMA6C,ITSN1,SORBS1,BCAS1,ARFGAP2,SLC8A3,ASPH,KBTBD12,IGSF9B,SOX5,CADM3,ZSWIM8,KIF1B,ADGRB2,NDUFA5,INKA2,RGL1,NKX2-2,CDK5R2,CACNB2,PTBP2,BRSK2,MFSD2A,PTGDR2,PRMT8,ADGRG1,DLGAP3,NRXN1,BEST1,RBPJ,USP54,ZBTB16,SYTL2,GON4L,CEP170,KCNK2,SLC17A6,PLEKHB2,GNE,LMO1" MicroRNA hsa-miR-20b-5p:Functional MTI Functional MTI miRTarbase 2.81E-17 1.52E-13 1.02E-16 9.36E-16 50 917 "ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,GPAM,USP16,RUFY2,CAPRIN2,GABBR1,SON,EMC1,SALL3,BCL2L2,SMOC1,ARHGEF7,LUZP2,GNAS,CAMTA1,WWC1,TCF7L2,PSD3,MFSD2A,TPM4,HMGB1,ZFYVE9,CCSER2,BTF3L4,NSD2,ACBD5,FEZ2,PRKACB,KIAA0513,CADM2,CEP170,CSDE1,OCIAD1,KCND3,RABGAP1L,WIPF2,RAB5B,ATG16L1,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100" MicroRNA hsa-miR-192*:mirSVR_highEffct hsa-miR-192*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.81E-17 1.52E-13 1.02E-16 9.36E-16 50 917 "RABEPK,ADAR,F3,KLHL32,BBOX1,MOBP,ITSN1,PKP4,NLGN1,SHTN1,AQP4,ZNF365,DACH2,SORCS3,SMARCE1,RCOR3,SON,CAB39,ZSWIM8,KIF1B,SPART,NDUFA5,ADHFE1,VAMP1,GNAS,CAMTA1,GNG4,MMD2,GRIA4,AIFM1,BEST3,HMGB1,PLEKHB1,HNRNPK,ST8SIA5,NSD2,CNRIP1,ETNPPL,OSBPL3,VCAN,DZIP3,PKN2,PRKCZ,NRSN1,TOX,SPIRE1,PTHLH,OLFM3,PAK5,SLC4A10" MicroRNA hsa-miR-132:PITA hsa-miR-132:PITA_TOP PITA 2.86E-17 1.55E-13 1.04E-16 9.52E-16 31 338 "MAPT,LGR4,ARID1A,SCN3A,LRRTM4,SEMA6A,SOX6,RPH3A,ARFGAP2,CCDC88A,DKK3,SOX5,SALL3,COLGALT2,NFIA,SEMA4A,CAMTA1,CAMSAP2,ADGRL3,PTBP2,GRM3,DCLK1,MED1,PPP2R5C,LRRTM3,CSDE1,KCNA6,SRGAP3,KCNK2,RBM12,EPB41" MicroRNA hsa-miR-212:PITA hsa-miR-212:PITA_TOP PITA 2.86E-17 1.55E-13 1.04E-16 9.52E-16 31 338 "MAPT,LGR4,ARID1A,SCN3A,LRRTM4,SEMA6A,SOX6,RPH3A,ARFGAP2,CCDC88A,DKK3,SOX5,SALL3,COLGALT2,NFIA,SEMA4A,CAMTA1,CAMSAP2,ADGRL3,PTBP2,GRM3,DCLK1,MED1,PPP2R5C,LRRTM3,CSDE1,KCNA6,SRGAP3,KCNK2,RBM12,EPB41" MicroRNA hsa-miR-187:mirSVR_lowEffct hsa-miR-187:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-17 1.60E-13 1.07E-16 9.81E-16 44 715 "SYT9,ADGRV1,GALNT13,SORCS1,TMEM156,AMER2,ANK2,ANK3,PPFIA1,TACC2,SORBS1,JAKMIP3,AQP4,IDI2-AS1,FXYD6,GFAP,ARHGEF7,ZNF638,GRIA4,RFFL,GRIN1,LGI1,TMEFF2,CP,CRMP1,RGS6,ATRNL1,PLCH2,RBPJ,MAPK10,EDRF1,PRDM2,PRTFDC1,CSDE1,PLPPR4,AK5,TMCC2,DPP6,DSCAM,DTNA,JMJD1C,RPRD1A,EPB41,EPB41L1" MicroRNA hsa-miR-151-3p:mirSVR_highEffct hsa-miR-151-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.95E-17 1.60E-13 1.07E-16 9.81E-16 40 589 "SDE2,TMEM74,PPFIA1,API5,PAAF1,AQP4,CCDC88A,SLCO1A2,DLL3,GABBR1,USP33,NPAS3,CLASP2,ERBIN,MLC1,GLS,BTRC,KLHL4,GPM6B,ZEB1,GRM3,TPD52,A2ML1,SULT4A1,CP,RNF14,RGS6,FEZ1,OSBPL3,PRKACB,FMN2,PKN2,NRSN1,MAPK8,BRINP3,SPIRE1,CEP170,PTPRZ1,WIPF2,PLEKHB2" MicroRNA hsa-miR-1268:mirSVR_lowEffct hsa-miR-1268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-17 1.68E-13 1.12E-16 1.03E-15 44 716 "MAG,SYT9,MEG3,FAM43B,LDLRAD3,FOXRED2,HOGA1,PLA2G6,TRIM46,ANK3,APBB1,CLSTN1,PKNOX2,SLC8A2,SCG3,LGI3,TMEM151A,ATP1A3,ZSWIM8,JPH4,GFAP,INKA2,SLCO1C1,CAMK2G,BRSK2,MFSD2A,PADI2,PDE2A,GPR37L1,JAM2,KIAA1549L,FTO,C11orf49,CELF5,PPP2R5C,FAM131B,HP1BP3,KCNJ4,RTN4,SYT15,SIDT2,LMO1,BSCL2,BAALC" MicroRNA hsa-miR-455-5p:mirSVR_highEffct hsa-miR-455-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.32E-17 1.80E-13 1.20E-16 1.10E-15 43 685 "ADGRV1,ADD3,CDC7,BBOX1,TRIM46,AMPH,USP28,CNIH2,JAKMIP3,MIER1,DACH2,ASPH,SORCS3,TNIK,B4GALNT1,STOX1,ERBIN,DCAF5,NELL1,CAMSAP2,GRIA4,TMEM25,TJP1,LGI1,PDE3B,MS4A7,PRRX1,NSD2,NXPH1,DZIP3,PRKCZ,PUM1,MASP1,GON4L,LRP8,AK5,KCNK2,DNM2,ATG16L1,DTNA,CRTAC1,RFX4,ARHGAP12" MicroRNA hsa-miR-1301:mirSVR_highEffct hsa-miR-1301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.35E-17 1.81E-13 1.21E-16 1.11E-15 49 886 "RTN3,ARID1A,MDM4,WAC,TOMM40L,TESK2,FGF1,ELMOD1,TRIM46,SELL,SEMA6C,ANK2,ANK3,RASA3,PPFIA1,ITSN1,MAGI3,ST3GAL3,SLC8A3,DACH2,SMARCE1,RCOR3,B3GAT1,MYT1L,CPLX2,CLASP2,ZNF302,ZNF638,SYT4,CDK5R2,KLHL4,ANO4,GPM6B,TPM3,FNDC5,MFSD4A,PHACTR3,PLPPR1,JAKMIP2,PMEPA1,PRDM2,SNX27,SLC25A48,DBX2,DTNA,ABCC9,SLC6A15,PRRT4,BAALC" MicroRNA hsa-miR-499-5p:PITA hsa-miR-499-5p:PITA_TOP PITA 3.36E-17 1.82E-13 1.21E-16 1.11E-15 26 224 "SDE2,ABAT,TESK2,SCN3A,SOX6,SOX5,AHCYL1,FAM168A,CACNB2,AZIN2,PTBP2,EML4,OMG,MS4A7,ACBD5,RNF14,RBPJ,FAM131B,PTCH1,DPP6,RET,RNF220,RBM12,ARHGAP12,SLC4A10,EPB41L2" MicroRNA hsa-miR-758:mirSVR_highEffct hsa-miR-758:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.84E-17 2.08E-13 1.38E-16 1.27E-15 45 753 "TTYH1,ABAT,ACLY,TMEM74,ADD3,FCGR1A,LRRTM4,CDC42BPA,RASA3,PAAF1,ZNF365,MIER1,SLC14A1,SORCS3,ATP2B2,GAD2,CLASP2,COLGALT2,NEUROD1,SYT4,UNC5D,PTBP2,EML4,GRIK2,CRB1,TMEM257,MAEL,MAGI1,BEST1,VCAN,SYTL2,PTCH1,DNAJC6,PLPPR1,CSDE1,OLFM3,NTM,SLC25A18,GOPC,GNE,DTNA,SLC6A15,GPR61,FGFBP3,SLC4A10" MicroRNA hsa-miR-612:mirSVR_highEffct hsa-miR-612:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.91E-17 2.12E-13 1.41E-16 1.30E-15 52 996 "ATAT1,RTKN,CLIP1,SORCS1,NLGN4X,SLC44A5,SNX32,FGF1,MOG,ITSN1,NTNG1,ARFGAP2,SPHKAP,CAPRIN2,SNCB,ATP2B2,MYBPC1,TNIK,B4GALNT1,NAP1L2,LMO3,GFAP,FAM168A,TMEM136,CACNB2,TCF12,PTBP2,INA,DAAM2,MAGI1,PRMT8,GPR37L1,GDAP1L1,P2RY12,FAT3,NXPH1,CHD1L,MED1,SF1,PPP3CB,ATRNL1,DZIP3,ECE2,LRRTM3,MAGI2,ZC3H11A,KCNK2,KCNMA1,RAD52,C12orf4,RET,ABI2" MicroRNA hsa-miR-455-3p:mirSVR_highEffct hsa-miR-455-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.00E-17 2.17E-13 1.44E-16 1.32E-15 49 890 "SDE2,RTN3,NLGN4X,LRRC7,PPFIA1,PKP4,NLGN1,ARFGAP2,SCG3,ASPH,RCOR3,MEGF11,DKK3,KIF1B,ADGRB2,SMOC1,ACSL6,ZEB1,NRGN,CECR2,GRIA2,GRIK2,PAX6,MAGI1,ANO5,CASC2,HERC2P3,TJP2,SLC25A27,CNRIP1,PNKD,PKN2,MASP1,SYTL2,SPIRE1,PTAFR,BDNF-AS,CSDE1,SLC17A6,C12orf4,RTN4,RET,RFX4,PHC2,ARHGAP12,CBLN2,SLC4A10,YY1AP1,EPB41L2" MicroRNA hsa-miR-1306-5p:TargetScan hsa-miR-1306-5p TargetScan 4.15E-17 2.25E-13 1.49E-16 1.37E-15 25 205 "RIMKLA,APC2,RCSD1,NDRG2,GOLGA7B,MOBP,APC,KIAA1614,ATP1A2,MYT1L,RAP1GAP2,COLGALT2,BCL2L2,DDR1,KCNK10,GPR37L1,PFKFB3,GDAP1L1,PTAFR,KCND3,CAB39L,FAM57B,PIANP,ABI2,ELAVL3" MicroRNA hsa-miR-552:mirSVR_highEffct hsa-miR-552:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.18E-17 2.27E-13 1.51E-16 1.38E-15 47 822 "ADGRV1,SORCS1,ADORA3,BBOX1,MOG,PKP4,NLGN1,API5,SLC8A3,NSG2,CADPS,CGREF1,SCG3,NEK6,TTLL9,ADHFE1,GANAB,NPPA,ZEB1,FBXL16,PDE1A,PRMT8,LINC01102,HPSE2,HNRNPK,BTF3L4,SPATA6,PACSIN1,NXPH1,POU3F2,PTPA,PPP3CB,PRKCZ,MAPK10,EDRF1,KLK6,PLPPR1,HP1BP3,CEP170,BLOC1S6,OCIAD1,PTPRE,PCDH15,WIPF2,RAD52,RASGRF1,ARHGAP12" MicroRNA hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA_TOP PITA 4.32E-17 2.34E-13 1.55E-16 1.43E-15 29 294 "CSMD3,SOX6,RCOR3,SOX5,SALL3,LMO3,DCAF5,RCOR2,CAMSAP2,GPM6A,PTBP2,NUDT21,EML4,GRIA4,DCLK1,TPM3,HNRNPK,NXPH1,PHACTR3,RAB39A,CTNND1,RIMS3,CEP170,SMG7,PTPRZ1,KCNMA1,SLC17A6,RBM12,RCAN2" MicroRNA hsa-miR-4267:mirSVR_highEffct hsa-miR-4267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.42E-17 2.39E-13 1.59E-16 1.46E-15 40 596 "MAG,SRARP,LGR4,SNX32,AGT,SEMA6A,TRIM46,ITSN1,APBB1,ZNF365,MSR1,DDX25,ADAM15,ADGRB2,VAMP1,PSRC1,ANO4,CECR2,LEFTY2,PIRT,ACOT7,TMPRSS5,CHGA,CPT1C,A2ML1,ST8SIA5,CHD1L,MED1,CRLS1,FEZ2,FMN2,PRKCZ,IGSF1,SMG7,PTPRO,KCNK2,FAM66C,BSDC1,ZYG11B,RFX4" MicroRNA hsa-miR-24:mirSVR_highEffct hsa-miR-24:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.55E-17 2.47E-13 1.64E-16 1.50E-15 42 659 "TTYH1,KIAA1109,LRRC7,FHL1,ITSN1,AQP4,ARFGAP2,EMC1,SALL3,NEK6,NEUROD1,SEMA4A,GPM6B,ACSL6,CACNA1E,VXN,USP2,MFSD2A,AIFM1,MAGI1,SERPINE2,BEST1,P2RY12,ACBD5,SNCAIP,NCAN,USP54,FGFR1OP2,SIRPA,PTHLH,PTPRD,PTPRE,PLPPR4,KCNK2,PCDH15,DNM2,GNE,VANGL2,SFXN5,LPAR6,SLC4A10,YY1AP1" MicroRNA hsa-miR-1182:mirSVR_highEffct hsa-miR-1182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.68E-17 2.54E-13 1.68E-16 1.54E-15 41 628 "SYT9,RCSD1,ARID1A,F3,HOGA1,LINC00461,HPCAL4,API5,LRRC55,SLC14A1,RCOR3,ATM,DKK3,TNIK,ZNF638,SEMA4A,ANO4,CACNB2,CAMK2G,LINC00839,HPS5,CDC42,DCLK1,ZNF384,ANO5,CASC2,CAMKV,NEGR1,A2ML1,ST8SIA5,FTO,SLC25A27,SPATA6,MED1,CRLS1,RBPJ,LRRTM3,PTPRO,FAM13C,RCAN2,BAALC" MicroRNA hsa-miR-558:mirSVR_highEffct hsa-miR-558:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.68E-17 2.54E-13 1.68E-16 1.54E-15 40 597 "ZFYVE27,MAP6,SYT9,TOMM40L,ASIC4,ELMOD1,PPFIA1,ITSN1,ZCCHC17,LRRC55,CGREF1,SPHKAP,NAXD,NPAS3,NDUFA5,ADHFE1,GLS,CAMTA1,CYB561A3,GRM3,LEFTY2,CDC42,LGI1,MAGI1,PDE1A,PDE4B,GDAP1L1,CADM1,FTO,CHD1L,SF1,PPP3CB,PROX1,CA10,PTPRE,KCNC1,DNM2,C12orf4,SLC4A10,EPB41L2" MicroRNA hsa-miR-362-5p:mirSVR_highEffct hsa-miR-362-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.91E-17 2.66E-13 1.76E-16 1.61E-15 45 758 "ADGRV1,ATAT1,LRRTM4,KIAA1109,LRRC7,BCAR3,ERICH3,SGIP1,ANK3,ITSN1,PAAF1,AQP4,ZNF365,ALDH4A1,NRG3,USP33,NAP1L2,ADHFE1,NEUROD1,CASTOR3,ZNF638,ANO4,LILRA1,AKNA,GPR88,NMT2,RNF14,KCNT2,PRKACB,ZNF385B,SYNC,PSMD13,BDNF-AS,PTHLH,OLFM3,OCIAD1,PTPRD,PTPRE,RABGAP1L,KCNMA1,DNM2,ABCC9,RFX4,SEC61A2,BAALC" MicroRNA hsa-miR-4269:mirSVR_highEffct hsa-miR-4269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.91E-17 2.66E-13 1.76E-16 1.61E-15 44 725 "RTN3,ADGRV1,CSMD2,ADCY2,SCN3A,LINC00461,FOXM1,PPFIA1,MAGI3,SLITRK3,SORBS1,ST3GAL3,PAAF1,ZNF365,SLC8A3,NAP1L2,ALDH1L1,NELL1,ADHFE1,GNAS,GOLGB1,DDR1,CACNB2,TMEM9,MAGI1,PRMT8,CCSER2,MEAF6,NXPH1,ATRNL1,IGSF1,WBP1L,DNAJC6,ITGAV,CSDE1,ZC3H11A,PTPRO,KCND3,KCNJ11,KCNK1,DLG2,DNM2,DTNA,RTN4" MicroRNA hsa-miR-324-3p:mirSVR_highEffct hsa-miR-324-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.10E-17 2.76E-13 1.83E-16 1.68E-15 38 538 "DUSP27,TOMM40L,CDC42BPA,PI16,CNIH2,ITSN1,APBB1,NTNG1,CACHD1,CGREF1,DNAH17,MTR,SORCS3,GABBR1,GANAB,ARHGEF7,DCLK2,NKX2-2,SEMA4A,ADAMTS8,TPM3,LINC01102,ZMYND8,CADM1,CAMKV,SLC25A27,CRMP1,ECE2,PRDM2,MAGI2,SV2A,RABGAP1L,DPP6,DSCAM,RPRD1A,ELAVL4,BSCL2,SEZ6" MicroRNA hsa-miR-760:TargetScan hsa-miR-760 TargetScan 5.13E-17 2.78E-13 1.84E-16 1.69E-15 34 424 "ABAT,CDHR1,MRVI1,ADARB2,ADCYAP1R1,GRAMD1B,FGF1,GOLGA7B,GPR153,ATP2B2,LHFPL4,BCL2L2,PHLDB1,CAMK2G,PSD3,REPS2,CDH8,RBFOX2,PDE2A,FNDC5,GPR37L1,PFKFB3,KIAA1549L,COL9A2,PRKAB2,DOCK7,PUM1,KIAA0513,KCNA6,PHC2,PIANP,GPR61,PLEKHO1,EPB41" MicroRNA hsa-miR-302f:PITA hsa-miR-302f:PITA_TOP PITA 5.42E-17 2.94E-13 1.94E-16 1.78E-15 28 273 "CSMD2,DSCAML1,SLITRK1,ERMN,LRRTM4,SGIP1,ANK3,NLGN1,SLC1A2,RCOR3,SOX5,MYH7,NEUROD1,ADGRL3,CACNA1E,CAMK2G,NEGR1,ST8SIA5,KIAA0408,RIMS3,SYNC,MAGI2,PTPRZ1,PID1,ABI1,GOPC,TTLL7,CBLN2" MicroRNA hsa-miR-361-3p:mirSVR_highEffct hsa-miR-361-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.55E-17 3.01E-13 1.98E-16 1.82E-15 31 346 "MEG3,SLC1A6,MSR1,SLC6A9,YPEL4,DLL3,JPH4,NCAM1,DCAF5,AJAP1,GNAS,DDR1,PTBP2,TGFBR3,TJP1,PCDH9,ZNF384,PDE1C,ZBED5,POU3F2,MED1,TOMM20,KCNA2,KCNJ4,KCNK1,KCNMA1,HS3ST4,ABI1,SLC6A15,FAM135B,EPB41" MicroRNA hsa-miR-648:PITA hsa-miR-648:PITA_TOP PITA 5.59E-17 3.03E-13 2.00E-16 1.83E-15 23 168 "CSMD3,BCAR3,TACC2,CAB39,NCAM1,ANO4,TBX15,GPM6A,PTBP2,GRIA2,GPR88,NEGR1,PRRX1,PLD5,USP54,CTNND1,PUM1,RIMS3,SV2A,RAB5B,JMJD1C,PIANP,ARHGAP12" MicroRNA hsa-miR-33a:PITA hsa-miR-33a:PITA_TOP PITA 6.47E-17 3.50E-13 2.31E-16 2.12E-15 26 230 "SLC25A25,GPR158,UNC79,CDC42BPA,ANK3,SLITRK3,B3GALT2,ENKUR,SALL3,CAMK2G,GPR88,TNS1,LGI1,TPM3,KIAA1549L,PACSIN1,PPP3CB,DPYSL5,KCNA4,KCNMA1,WIPF2,SLC17A6,GOPC,SLC6A15,SLC4A10,EN2" MicroRNA hsa-let-7a:mirSVR_highEffct hsa-let-7a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.68E-17 3.62E-13 2.38E-16 2.19E-15 46 798 "LGR4,MEG3,ARID1A,MDM4,KLHL32,ERMN,FGR,SESN3,PAAF1,GABBR1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,PCDH11X,ACSL6,CACNB2,ADAMTS8,CRB1,TGFBR3,AIFM1,PDE3B,SERPINE2,SLC25A27,PRRX1,MFSD4A,OSBPL3,IGSF1,MASP1,SYNC,PRDM2,PTPRO,KCNJ11,KCNK1,DLG2,KIF2A,TMEM255A,DPP6,C12orf4,SLC25A18,DTNA,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-4291:mirSVR_highEffct hsa-miR-4291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.74E-17 3.65E-13 2.40E-16 2.20E-15 51 973 "CNTNAP3,RCSD1,EYA1,ATAT1,ARID1A,MDM4,SLITRK1,CDC7,ADORA3,ANK3,NLGN1,ST3GAL3,API5,SHTN1,SMARCE1,SNCB,MYT1L,KIF21B,AHCYL1,ARPP21,CLASP2,BCL2L2,GPR162,GLS,ZNF638,CACNA1A,GPM6B,CACNB2,GRIA2,RFFL,TGFBR3,PDE3B,PRMT8,CASC2,CADM1,NOMO2,MEAF6,P2RY12,VCAN,PLD5,PTHLH,LRP8,PTPRD,SMG7,KCNJ11,HS3ST4,RAB5B,DPP6,ATG16L1,BSDC1,SEC61A2" MicroRNA hsa-miR-361-3p:PITA hsa-miR-361-3p:PITA_TOP PITA 6.86E-17 3.72E-13 2.44E-16 2.24E-15 22 151 "PDZD4,YPEL4,ATP1A3,WDTC1,ZSWIM8,CPLX2,NCAM1,AJAP1,BTRC,FBXL16,ZNF384,NRXN2,PRRX1,POU3F2,MED1,FAM131B,ZC3H11A,SV2A,DLG2,ABI1,ELAVL3,RASGRP2" MicroRNA hsa-miR-223:PITA hsa-miR-223:PITA_TOP PITA 7.20E-17 3.90E-13 2.56E-16 2.35E-15 26 231 "ARID1A,F3,DSCAML1,SCN3A,PKP4,APC,CLSTN1,CSPG5,CAPRIN2,NFASC,NFIA,CAMTA1,BTRC,PTBP2,GRIA4,OPCML,HAPLN2,RBPJ,PKN2,CTNND1,TOX,WBP1L,SRGAP3,TMEM255A,FAM13C,PAK5" MicroRNA hsa-miR-571:mirSVR_highEffct hsa-miR-571:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.26E-17 3.93E-13 2.58E-16 2.37E-15 39 574 "RABEPK,ATAT1,RTKN,DSCAML1,FCGR1A,DOCK10,MAGI3,SHTN1,SLC1A6,ARHGAP5,SLN,ATP1A2,NPAS3,LMO3,ADHFE1,GANAB,ROBO3,CAMSAP2,GOLGB1,PTBP2,VSTM2A,GRID1,ZNF384,CASC2,NLGN3,CADM1,OPALIN,PRKACB,FMN2,PUM1,OCIAD1,SV2A,RABGAP1L,RAB5B,RTN4,ZNF248,RPRD1A,ABI2,BAALC" MicroRNA hsa-let-7g:mirSVR_highEffct hsa-let-7g:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.34E-17 3.98E-13 2.61E-16 2.39E-15 46 800 "LGR4,MDM4,CLIP1,KLHL32,SESN3,PAAF1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,PCDH11X,GNAS,ACSL6,CACNB2,ADAMTS8,CRB1,TGFBR3,AIFM1,PDE3B,SERPINE2,PMP2,SLC25A27,PRRX1,MFSD4A,OSBPL3,PLPP4,IGSF1,MASP1,SYNC,BDNF-AS,PRDM2,PTPRO,KCNJ11,DLG2,KIF2A,TMEM255A,DPP6,C12orf4,SLC25A18,DTNA,RTN4,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-138-5p:TargetScan hsa-miR-138-5p TargetScan 7.66E-17 4.15E-13 2.72E-16 2.50E-15 36 486 "RIMKLA,CLIP1,ADCYAP1R1,GPR158,ANK1,GAS7,MEGF11,SCN3B,KIF21B,ILDR2,NEUROD1,NFIA,RHBDL3,CACNA1A,HAP1,GRID1,DAAM2,CADM1,CELF5,ATCAY,PLCH2,RIMS4,RBPJ,SDC3,PROX1,RIMS3,RGMA,KCNH1,NTM,DLG3,NKAIN1,CALN1,JMJD1C,EN2,PRRT4,RCAN2" MicroRNA hsa-miR-328:mirSVR_highEffct hsa-miR-328:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.99E-17 4.32E-13 2.83E-16 2.60E-15 33 403 "LGR4,LDLRAD3,TESK2,LRRTM4,ERICH3,ITSN1,SLITRK3,PAAF1,SLIT1,MTR,TTLL9,FXYD6,NDUFA5,NELL1,NEUROD1,GPM6A,TCF7L2,INA,P2RX7,TNR,PADI2,HEPACAM,DUSP26,PMP2,CHD1L,MED1,PLPPR5,PTHLH,PCDH15,KIF2A,RALGDS,VWA5A,EN2" MicroRNA hsa-miR-519d-3p:Functional MTI Functional MTI miRTarbase 8.09E-17 4.38E-13 2.87E-16 2.63E-15 49 906 "ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,USP28,SESN3,GPAM,USP16,RUFY2,CAPRIN2,GABBR1,SON,EMC1,SALL3,BCL2L2,SMOC1,ARHGEF7,LUZP2,GNAS,CAMTA1,WWC1,TCF7L2,MFSD2A,TPM4,HMGB1,ZFYVE9,CCSER2,BTF3L4,NSD2,ACBD5,FEZ2,PRKACB,KIAA0513,CADM2,CEP170,CSDE1,OCIAD1,KCND3,RABGAP1L,WIPF2,RAB5B,ATG16L1,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100" MicroRNA hsa-miR-629:mirSVR_highEffct hsa-miR-629:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-17 4.53E-13 2.97E-16 2.72E-15 45 769 "SYT9,ATAT1,WAC,SORCS1,ERMN,SNX30,GPR158,FGF1,USP28,SLC14A1,CADPS,ASPH,RCOR3,ATM,SOX5,GAD2,NCAM1,ALDH1L1,NCDN,GANAB,LUZP2,TCF7L2,GPR88,PAX6,CDH10,SLC22A6,TJP2,CNTN1,MEAF6,MED1,ATRNL1,RBPJ,PLPP4,USP54,MAPK10,MASP1,SYTL2,PSMD13,MAGI2,PTPRD,SMG7,KCNK2,RFX4,ARHGEF10L,BAALC" MicroRNA hsa-miR-1262:mirSVR_highEffct hsa-miR-1262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.28E-17 5.03E-13 3.29E-16 3.02E-15 46 805 "WLS,ADD3,NLGN4X,AGT,CNIH2,PKP4,SESN3,NTNG1,CCDC80,ZCCHC17,BCAN,MSR1,SLC8A3,SMARCE1,RCOR3,NRG3,ENKUR,SALL3,KIF1B,NCAM1,C11orf87,COLGALT2,ARHGEF7,VAMP1,GNAS,ADGRL3,KLHL4,CACNB2,DDR2,LEFTY2,TJP1,FNDC5,PLXNB3,BEST1,SF1,DOCK7,ZNF385B,LRRTM3,CA10,CADM2,LRP8,AK5,DLG2,FAM13C,RFX4,YY1AP1" MicroRNA hsa-miR-921:mirSVR_highEffct hsa-miR-921:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.55E-17 5.17E-13 3.38E-16 3.10E-15 42 673 "LOC100128239,ADGRV1,EYA1,NDRG2,ADD3,SLC44A5,CNIH2,MAGI3,SLITRK3,MIER1,SLC1A6,CCDC88A,DKK3,SON,ENKUR,GART,LMO3,CLASP2,NDUFA5,BTRC,ADGRL3,LILRA1,RBFOX2,TMPRSS5,MS4A7,CADM1,ANLN,A2ML1,CNRIP1,POU3F2,USP54,IGSF1,PUM1,SYNC,BDNF-AS,COPS7A,PCDH15,KCNN3,PID1,DTNA,ABCC9,ELAVL4" MicroRNA hsa-miR-369-3p:TargetScan hsa-miR-369-3p TargetScan 9.68E-17 5.24E-13 3.42E-16 3.14E-15 35 461 "ABAT,ACLY,EYA1,CSMD2,GRAMD1B,AMER2,FOXG1,GAS7,ARHGAP5,PDE8B,FYN,SCN3B,NFIA,GRIA1,PAX6,DCLK1,RBFOX2,PDE3B,PHACTR3,RBPJ,PRKAB2,PLD5,DNAJC6,CDH20,OCIAD1,RABGAP1L,KCNN3,DLG3,RAB5B,GOPC,BSDC1,RFX4,JMJD1C,PIANP,EPB41" MicroRNA hsa-let-7d:mirSVR_highEffct hsa-let-7d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-16 5.49E-13 3.58E-16 3.29E-15 45 773 "LGR4,RTKN,MDM4,KLHL32,ERMN,SESN3,PAAF1,GABBR1,KIF1B,CLASP2,ADHFE1,GANAB,ACSL6,CACNB2,TCF12,ADAMTS8,GPR88,CRB1,TGFBR3,AIFM1,SERPINE2,A2ML1,PMP2,SLC25A27,PRRX1,MFSD4A,OSBPL3,RBPJ,IGSF1,MASP1,SYNC,PRDM2,PTPRO,KCNJ11,DLG2,KIF2A,TMEM255A,DPP6,C12orf4,SLC25A18,DTNA,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-507:PITA hsa-miR-507:PITA_TOP PITA 1.06E-16 5.74E-13 3.74E-16 3.43E-15 29 304 "SORCS1,NLGN4X,SCN3A,UNC79,AMPH,ARHGAP5,RCOR3,ATP2B2,B3GALT2,B4GALNT1,NEUROD1,NKX2-2,ADGRL3,ANO4,HAP1,GRIK2,TMEM257,PCDH9,HNRNPK,BTF3L4,DZIP3,FMN2,PRDM2,KCNA1,PTPRD,DLG2,DLG3,ABI1,DSCAM" MicroRNA hsa-miR-557:PITA hsa-miR-557:PITA_TOP PITA 1.06E-16 5.74E-13 3.74E-16 3.43E-15 29 304 "SORCS1,NLGN4X,SCN3A,UNC79,AMPH,ARHGAP5,RCOR3,ATP2B2,B3GALT2,B4GALNT1,NEUROD1,NKX2-2,ADGRL3,ANO4,HAP1,GRIK2,TMEM257,PCDH9,HNRNPK,BTF3L4,DZIP3,FMN2,PRDM2,KCNA1,PTPRD,DLG2,DLG3,ABI1,DSCAM" MicroRNA hsa-miR-155:PITA hsa-miR-155:PITA_TOP PITA 1.06E-16 5.74E-13 3.74E-16 3.43E-15 29 304 "ADD3,SORCS1,ELMOD1,SGIP1,ASTN1,PALLD,SOX1,CAB39,RGL1,NFIA,GNAS,CAMTA1,WWC1,TCF12,REPS2,PCDH9,CCSER2,PKN2,TOMM20,KCNA1,PTPRD,KCNN3,PLEKHB2,PAK5,SLC6A15,SEC61A2,LPAR6,SLC4A10,EN2" MicroRNA hsa-miR-892b:mirSVR_highEffct hsa-miR-892b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-16 5.95E-13 3.87E-16 3.55E-15 47 843 "PRR5L,ACHE,TMEM74,SYT9,CLIP1,SORCS1,TMEM156,ADORA3,UNC79,HPCAL4,AMPH,SH3GL2,APC,NTNG1,CCDC80,ATM,TTLL9,IDI2-AS1,NCAM1,ZNF638,MMD2,TBX15,ZEB1,PCDHGA3,GRIA2,GPR88,OMG,TJP1,NRXN1,PRKACB,DOCK7,DZIP3,PRKCZ,IGSF1,MAPK10,CA10,CADM2,KCNMA1,DNAH9,DSCAM,SLC6A15,JMJD1C,ZNF248,SSPN,SLC4A10,ELAVL4,TMEM100" MicroRNA hsa-miR-186*:mirSVR_highEffct hsa-miR-186*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-16 6.54E-13 4.26E-16 3.91E-15 48 880 "PAQR6,CSMD2,TESK2,KIAA1109,BCAR3,MOBP,ANXA7,PKP4,NTNG1,CACHD1,NLGN1,PAAF1,MSR1,LRRC55,ASPH,SORCS3,KIF1B,CLASP2,ADHFE1,GLS,SYT4,CAMTA1,ADGRL3,CACNA1A,GPM6B,VWC2,VSTM2A,TPM4,MAGI1,PRMT8,GPR37L1,CNTN1,MEAF6,CELF5,NSD2,MED1,CHD5,NCAN,PRKACB,USP54,BDNF-AS,PTHLH,SMG7,SV2A,NTM,KCNK1,PCDH15,ABCC9" MicroRNA hsa-miR-485-5p:PITA hsa-miR-485-5p:PITA_TOP PITA 1.26E-16 6.84E-13 4.45E-16 4.08E-15 24 194 "SDE2,LRRC7,CNIH2,ATP2B2,SOX5,LHFPL4,RND1,NRGN,GRIN1,ZFP91,MAGI1,ZNF384,MED1,SF1,FEZ1,ATRNL1,PSD,CADM2,KCNA1,TMCC2,SNX27,PHC2,RNF220,EPB41L2" MicroRNA hsa-miR-1303:PITA hsa-miR-1303:PITA_TOP PITA 1.29E-16 7.01E-13 4.55E-16 4.18E-15 27 259 "MAG,SORCS1,LRRTM4,FGF1,PPM1E,TACC2,API5,SHTN1,GAD2,DNER,CAMSAP2,VWC2,TCF12,OPCML,TJP1,PCDH9,RBFOX2,MAGI1,POU3F2,PUM1,PTCH1,CADM2,ELMO1,KCNA1,PTPRD,ZYG11B,INSYN2" MicroRNA hsa-miR-1910:mirSVR_highEffct hsa-miR-1910:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-16 7.20E-13 4.68E-16 4.29E-15 43 712 "SDE2,ACER3,MEG3,SORCS1,GPR158,ANK3,ITSN1,ST3GAL3,RPH3A,MT3,SCMH1,SORCS3,EIF4G3,TNIK,COLGALT2,BCL2L2,RND1,KAZN,ANO4,PTBP2,GRM3,CRB1,MFSD2A,AIFM1,TPM3,PDE1A,PDE3B,FNDC5,TJP2,MED1,SNCAIP,RBPJ,PUM1,SPIRE1,LRRTM3,COPS7A,SMG7,PCDH15,GOPC,CAMK1G,RGS10,SEC61A2,YY1AP1" MicroRNA hsa-miR-106a-5p:Functional MTI Functional MTI miRTarbase 1.47E-16 7.96E-13 5.16E-16 4.74E-15 43 714 "RTN3,ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,SESN3,APC,RPH3A,RUFY2,ARHGAP5,CAPRIN2,ATM,SON,EMC1,SALL3,BCL2L2,SMOC1,LUZP2,WWC1,TCF7L2,MFSD2A,TPM4,HMGB1,ZFYVE9,BTF3L4,PRKACB,KIAA0513,SIRPA,CADM2,CEP170,CSDE1,OCIAD1,KCND3,RABGAP1L,WIPF2,RAB5B,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100" MicroRNA hsa-miR-338-3p:PITA hsa-miR-338-3p:PITA_TOP PITA 1.62E-16 8.79E-13 5.70E-16 5.23E-15 25 217 "SNX30,SEMA6A,MYT1L,CPLX2,LMO3,CLASP2,DCAF5,NEUROD1,CDK5R2,EML4,GRIA2,TNFRSF1B,CADM1,KIAA1549L,RGS6,CADM2,SV2A,SRGAP3,KCNMA1,DLG2,TMEM255A,ABI1,RGS7,ARHGEF10L,SEC61A2" MicroRNA hsa-miR-184:mirSVR_lowEffct hsa-miR-184:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-16 9.08E-13 5.89E-16 5.40E-15 34 441 "MAP6,SNX32,GOLGA7B,PKP4,SLC6A9,NAXD,ALDH4A1,WDTC1,SOX1,KIF21B,ADGRB2,ARHGEF7,GLS,VAMP1,CAMTA1,ATF7,CYB561A3,CRB1,ZDHHC22,CDC42,TNS1,DCLK1,ZMYND8,PLEKHB1,POU3F2,MICAL2,SIRPA,ATG16L1,ABCC9,PIANP,RBM12,LMO1,EPB41L1,BAALC" MicroRNA hsa-miR-1197:mirSVR_highEffct hsa-miR-1197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.77E-16 9.57E-13 6.20E-16 5.69E-15 44 751 "ADGRV1,FAM43B,ADD3,FABP7,GPR158,FHL1,PKP4,CLSTN1,MADD,CCDC88A,DDX25,SORCS3,SNAP25,ATM,PHYHIPL,USP33,TNIK,CAB39,NPAS3,RGL1,ZNF638,CACNB2,ZEB1,CECR2,PTPN5,P2RX7,DAAM2,DCLK1,PDYN,FAM181B,FEZ2,USP54,GON4L,TUBB2B,CA10,CEP170,BLOC1S6,ZC3H11A,PTPRO,PTPRZ1,KCNK1,SUSD4,PIANP,VWA5A" MicroRNA hsa-miR-1260b:mirSVR_highEffct hsa-miR-1260b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-16 9.66E-13 6.25E-16 5.74E-15 40 621 "RABEPK,RTKN,LRRTM4,CDC42BPA,ITSN1,SORBS1,ZNF365,MIER1,MSRA,SLC8A3,CAPRIN2,ARPP21,GFAP,ADHFE1,AJAP1,ZNF638,NODAL,PTBP2,GRIA4,TNR,ZNF384,NRXN2,CHD1L,RNF14,CTNND1,NRSN1,GON4L,ITGAV,BDNF-AS,PTPRD,KCNK2,PCDH15,KCNN3,C12orf4,DSCAM,BSDC1,RET,EPB41,EPB41L1,SEZ6" MicroRNA hsa-miR-512-3p:mirSVR_highEffct hsa-miR-512-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-16 9.68E-13 6.26E-16 5.75E-15 45 785 "SYT9,RTN3,SYNDIG1,KLHL32,APC,MAGI3,DACH2,MTR,PHYHIPL,SON,MYT1L,ILDR2,CLASP2,ADHFE1,DCLK2,KAZN,GNAS,CAMTA1,ZEB1,PTBP2,GRIK3,CCKBR,LINC00839,CRB1,LINC01102,TJP2,PLXNB3,MFSD4A,FMN2,PLPP4,MAPK10,TOX,ANKS1B,PLPPR5,CADM2,HP1BP3,PTPRO,PCDH15,SLC6A15,RFX4,JMJD1C,ZNF248,EFNA3,RPRD1A,SLC4A10" MicroRNA hsa-miR-34b*:mirSVR_highEffct hsa-miR-34b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.96E-16 1.06E-12 6.85E-16 6.28E-15 53 1073 "MBP,ATAT1,MDM4,GPR158,SCN3A,LRRC7,ELMOD1,SLC30A10,ANK2,ANK3,ITSN1,ST3GAL3,API5,ASCL1,SCG3,CAPRIN2,ATM,PALLD,SON,B3GALT2,TNIK,ARPP21,KIF1B,NPAS3,RAP1GAP2,ERBIN,NEUROD1,GNAS,GOLGB1,CACNA1A,GPM6B,PTBP2,TMEM25,DCLK1,LGI1,MAGI1,UBTF,SULT4A1,NSD2,CTNND2,PUM1,MASP1,TOX,ANKS1B,GON4L,PTHLH,CADM2,KCNA1,RABGAP1L,ARNT2,KCNMA1,DPP6,JMJD1C" MicroRNA hsa-miR-1183:PITA hsa-miR-1183:PITA_TOP PITA 2.03E-16 1.10E-12 7.08E-16 6.50E-15 24 198 "HPCAL4,SGIP1,CDC42BPA,ANK3,APC,CADPS,NELL1,PSD3,GRIA2,TJP1,DAAM2,MAEL,LGI1,PDE4B,NEGR1,PTCH1,DNAJC6,ITGAV,KCNA2,PTPRD,PTPRO,DLG2,ZYG11B,VANGL2" MicroRNA hsa-miR-146a:mirSVR_highEffct hsa-miR-146a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.05E-16 1.11E-12 7.16E-16 6.57E-15 52 1037 "SYT9,LDLRAD3,KIAA1109,LRRC7,FHL1,AMPH,ITSN1,SH3GL2,SESN3,ZNF365,CCDC88A,DACH2,CSPG5,CAPRIN2,PHYHIPL,USP33,B3GALT2,CLASP2,COLGALT2,DCAF5,DDHD2,CAMSAP2,ADGRL3,KLHL4,EML4,GRID1,USP2,MFSD2A,CELF3,CDH10,DNAJC12,SLC25A27,BTF3L4,POU3F2,MED1,USP54,IGSF1,PUM1,TOX,PLPPR5,ZNF385B,LRRTM3,CADM2,HP1BP3,PTPRE,KCNK2,PID1,DTNA,SLC6A15,INSYN2,C2orf80,TMEM100" MicroRNA hsa-miR-432*:mirSVR_highEffct hsa-miR-432*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.14E-16 1.16E-12 7.48E-16 6.86E-15 39 593 "SYT9,SCN3A,ASIC4,ITSN1,MAGI3,BCAS1,SORCS3,TMEM108,PHYHIPL,GPR162,HEPN1,NELL1,FAM168A,CAMTA1,CNDP1,GPM6A,LRIT2,NUCB1,GRIK3,OPCML,PTPN5,PTGDR2,SEZ6L,PDE3B,PLEKHB1,CADM1,SLC25A27,SPATA6,OSBPL3,TOX,PLPPR5,ITGAV,CADM2,PTPRO,SLC17A6,RASGRF1,CRTAC1,SSPN,VWA5A" MicroRNA hsa-miR-1979:mirSVR_highEffct hsa-miR-1979:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-16 1.26E-12 8.09E-16 7.42E-15 48 895 "MDM4,ERMN,NLGN4X,FCGR1A,FHL1,SOX6,PPFIA1,ITSN1,MADD,SLC8A3,CAPRIN2,SMARCE1,RCOR3,SNAP25,TNIK,KIF1B,COLGALT2,SMOC1,NKX2-2,BTRC,ZEB1,CECR2,GRIA2,GRIA4,CCKBR,TMEM25,TLL2,TMEM257,MAGI1,MS4A7,NLGN3,NRXN1,RGS6,NCAN,DOCK7,GON4L,PTPRD,SMG7,NTM,PCDH15,PEX5,KLRC2,SLC25A48,DTNA,L1CAM,SLC6A15,JMJD1C,SLC4A10" MicroRNA hsa-miR-34a:mirSVR_highEffct hsa-miR-34a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.33E-16 1.26E-12 8.11E-16 7.44E-15 46 825 "LGR4,MDM4,GPR158,LRRC7,ELMOD1,HPCAL4,FOXG1,ANK2,ANK3,PPFIA1,ITSN1,PKP4,ZCCHC17,RUFY2,SORCS3,PALLD,KIF1B,ARHGEF7,GNAS,DDHD2,CAMTA1,GOLGB1,ANO4,GRID1,INA,TNR,LGI1,TPD52,GDAP1L1,CADM1,ST8SIA5,SULT4A1,SLC25A27,CRLS1,IGSF1,CTNND2,NOS1AP,SYNC,MAGI2,KCNA2,PTPRD,TMEM255A,SLC6A15,JMJD1C,SYT15,VWA5A" MicroRNA hsa-miR-340:PITA hsa-miR-340:PITA_TOP PITA 2.34E-16 1.27E-12 8.15E-16 7.48E-15 40 626 "ARID1A,CSMD3,LRRC7,MAGI3,GAS7,API5,SLC1A2,ASCL1,CAPRIN2,RCOR3,TMEM108,PALLD,MYT1L,NEK6,DCAF5,LUZP2,CAMTA1,CAMSAP2,ADGRL3,CAMK2A,SYT6,RFFL,TNS1,MAGI1,POU3F2,MICAL2,RIMS4,PKN2,PUM1,ITGAV,CADM2,MAGI2,KCNA4,PTPRE,KCNK1,TMEM255A,CALN1,GOPC,RNF220,ELAVL4" MicroRNA hsa-miR-4320:mirSVR_highEffct hsa-miR-4320:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-16 1.28E-12 8.21E-16 7.54E-15 44 757 "ACER3,SYT9,IL17D,ARID1A,ADARB2,FOLH1,SCG3,SOX5,KIF1B,C11orf87,NELL1,ZNF638,LUZP2,GOLGB1,PRUNE2,GRIA1,GRIA2,GRIA4,INA,P2RX7,TNS1,PCDH9,ARHGAP19,CHGA,DLGAP3,PRKAB2,PRKACB,MAPK10,WBP1L,ANKS1B,CA10,ELMO1,COPS7A,CSDE1,PTPRE,KCNK1,DLG2,DLG3,KLRC2,JMJD1C,FAM135B,INSYN2,SFXN5,CBLN2" MicroRNA hsa-miR-3132:mirSVR_highEffct hsa-miR-3132:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.41E-16 1.30E-12 8.38E-16 7.69E-15 42 691 "RABEPK,LDLRAD3,KCNIP2,ADAR,DSCAML1,AGT,FGR,AMPH,APC,BCAN,CAPRIN2,GAD2,DCAF5,GANAB,NFIA,GLS,VAMP1,KAZN,GNAS,EML4,GRID1,MFSD2A,PAX6,TNR,CDH10,PDE1A,HMGB1,SEMA5B,SULT4A1,SPATA6,ATRNL1,NRSN1,CA10,AK5,KCNK1,DLG3,DTNA,CAMK1G,RFX4,RFX5,RPRD1A,VWA5A" MicroRNA hsa-miR-493:mirSVR_highEffct hsa-miR-493:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.60E-16 1.41E-12 9.05E-16 8.30E-15 41 660 "RABEPK,ACTN2,MRVI1,ADORA3,TRIM46,PKP4,JAKMIP3,PAAF1,PKNOX2,DACH2,CADPS,TAGLN3,ASPH,SMARCE1,RCOR3,TMEM108,B3GALT2,ZNF302,ZNF638,NKX2-2,CACNB2,NUDT21,PCDHGA3,CAMK2G,CECR2,CCKBR,INA,CELF3,LGI1,PCSK2,ST8SIA5,CELF5,KCNT2,FEZ1,ECE2,GON4L,PTHLH,PTPRZ1,KCNJ9,SUSD4,PAK5" MicroRNA hsa-miR-888:PITA hsa-miR-888:PITA_TOP PITA 2.69E-16 1.45E-12 9.34E-16 8.57E-15 33 420 "RIMKLA,DUSP27,RTN1,ADD3,TESK2,ELMOD1,FOXG1,ITSN1,PPM1E,GPAM,SNAP25,DKK3,ZCCHC24,NMNAT2,DNER,CLASP2,COLGALT2,SYT4,ADGRL3,GRIA2,CDC42,MAGI1,CADM1,CELF5,SLC25A27,WBP1L,LRRTM3,ITGAV,PMEPA1,DLG2,CALN1,GOPC,ZYG11B" MicroRNA hsa-miR-139-5p:TargetScan hsa-miR-139-5p TargetScan 2.73E-16 1.48E-12 9.49E-16 8.71E-15 29 315 "MRVI1,NDRG2,GALNT13,ADCYAP1R1,SCN3A,SCN4B,ANK1,ANK2,ATP2B2,AJAP1,FAM168A,NFIA,CECR2,FBXL16,PCDH9,CDH8,RBFOX2,CADM1,NEGR1,FAT3,NXPH1,MAPK8,DPYSL5,JAKMIP2,CDH20,PTPRD,KCND3,DPP6,RASGRF1" MicroRNA hsa-miR-553:mirSVR_lowEffct hsa-miR-553:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-16 1.49E-12 9.54E-16 8.75E-15 40 629 "MBP,ADCY2,ADD3,LRRTM4,DOCK10,SESN3,GPAM,CACHD1,SYBU,LRRC4C,ARHGAP5,ARFGAP2,SHANK2,WDTC1,SPART,CLASP2,NEUROD1,ARHGEF7,DDHD2,LRIT2,TCF7L2,GRIA4,TJP1,TPD52,PRMT8,JAM2,VAV2,SNCAIP,DOCK7,USP54,EDRF1,WBP1L,ANKS1B,ZNF385B,PLPPR4,NTM,RASGRF1,GNE,SH3GLB1,RPE65" MicroRNA hsa-miR-3164:mirSVR_highEffct hsa-miR-3164:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-16 1.52E-12 9.72E-16 8.92E-15 51 1008 "SRARP,ADAR,WAC,AMER2,FCGR1A,LRRTM4,KIAA1109,ELMOD1,MAGI3,GPAM,SLITRK3,MSRA,LRRC55,DACH2,SPHKAP,DKK3,NCAM1,SLCO1C1,ARHGEF7,CAMSAP2,ADGRL3,WWC1,VWC2,PTBP2,NUMA1,GRIA4,GRIK2,OLR1,TGFBR3,INA,TJP1,TMEM257,PCDH9,MAGI1,FNDC5,NRXN1,ANLN,TJP2,MEAF6,BEST1,RNF14,PPP3CB,VCAN,LRRTM3,PLPPR1,OCIAD1,NTM,DTNA,PAK5,ABCC9,FAM135B" MicroRNA "TGCACTT,MIR-519C:MSigDB" "TGCACTT,MIR-519C:MSigDB" MSigDB 2.88E-16 1.56E-12 9.97E-16 9.15E-15 33 421 "RTN1,TESK2,FOXG1,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,MYRF,ZFP91,HPS5,ZFYVE9,BTF3L4,NSD2,PSD,KIAA0513,CA10,PTHLH,SRGAP3,KCNJ10,KCNQ2,RAB5B,DNM2,RAD52,ATG16L1,GOPC,ARHGAP12" MicroRNA "TGCACTT,MIR-519A:MSigDB" "TGCACTT,MIR-519A:MSigDB" MSigDB 2.88E-16 1.56E-12 9.97E-16 9.15E-15 33 421 "RTN1,TESK2,FOXG1,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,MYRF,ZFP91,HPS5,ZFYVE9,BTF3L4,NSD2,PSD,KIAA0513,CA10,PTHLH,SRGAP3,KCNJ10,KCNQ2,RAB5B,DNM2,RAD52,ATG16L1,GOPC,ARHGAP12" MicroRNA "TGCACTT,MIR-519B:MSigDB" "TGCACTT,MIR-519B:MSigDB" MSigDB 2.88E-16 1.56E-12 9.97E-16 9.15E-15 33 421 "RTN1,TESK2,FOXG1,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,SOX5,BCL2L2,SMOC1,ERBIN,NFIA,NHLH1,MYRF,ZFP91,HPS5,ZFYVE9,BTF3L4,NSD2,PSD,KIAA0513,CA10,PTHLH,SRGAP3,KCNJ10,KCNQ2,RAB5B,DNM2,RAD52,ATG16L1,GOPC,ARHGAP12" MicroRNA hsa-miR-548q:mirSVR_highEffct hsa-miR-548q:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-16 1.57E-12 1.00E-15 9.22E-15 37 537 "SYNDIG1,CLIP1,GRAMD1B,TMEM156,ADORA3,GPAM,ST3GAL3,PAAF1,ZSWIM8,B4GALNT1,C11orf87,ADHFE1,GLS,NHLH1,CAMTA1,PRLHR,GPR19,CDH8,TPM4,BEST3,KIAA1549L,ACBD5,POU3F2,CHD1L,SNCAIP,KCNT2,MICAL2,OSBPL3,PKN2,BRINP3,TOMM20,CA10,DNAH9,RET,SEC61A2,RBM12,EPB41L2" MicroRNA hsa-miR-1228:PITA hsa-miR-1228:PITA_TOP PITA 2.99E-16 1.62E-12 1.03E-15 9.48E-15 23 181 "SDE2,EYA1,ARID1A,FOXG1,PKP4,MYT1L,NPAS3,RGL1,NFIA,CAMTA1,TJP1,CDH10,HRH3,PCSK2,CADM1,NRXN1,MAPK10,PTPRD,SMG7,SRGAP3,WIPF2,RBM12,EN2" MicroRNA hsa-miR-647:mirSVR_highEffct hsa-miR-647:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.04E-16 1.65E-12 1.05E-15 9.64E-15 41 663 "RABEPK,MEG3,ARID1A,WLS,ADORA3,ANK2,CCDC80,PAAF1,MIER1,SLCO1A2,CAPRIN2,RCOR3,TTLL9,FXYD6,NFASC,PCDH11X,DCLK2,ANO4,ZEB1,CAMK2G,SYT6,GRIA2,TMEM257,TNR,PDE3B,HPCA,PRRX1,MFSD4A,CHD1L,MED1,DZIP3,PSMD13,CA10,PLPPR1,KCNK1,ABCC9,ZYG11B,NUP214,SEC61A2,PIANP,FGFBP3" MicroRNA hsa-miR-1260:mirSVR_highEffct hsa-miR-1260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.06E-16 1.65E-12 1.06E-15 9.69E-15 40 631 "RABEPK,RTKN,ADORA3,LRRTM4,CDC42BPA,ITSN1,SORBS1,ZNF365,MIER1,MSRA,SLC8A3,CAPRIN2,ARPP21,GFAP,ADHFE1,AJAP1,ZNF638,NODAL,PTBP2,TNR,ZNF384,NRXN2,CHD1L,RNF14,CTNND1,NRSN1,ECE2,GON4L,ITGAV,BDNF-AS,KCNK2,PCDH15,KCNN3,C12orf4,DSCAM,BSDC1,RET,EPB41,EPB41L1,SEZ6" MicroRNA hsa-miR-183-5p.1:TargetScan hsa-miR-183-5p.1 TargetScan 3.13E-16 1.69E-12 1.08E-15 9.90E-15 31 368 "MRVI1,MDM4,SCN3A,PKP4,PPM1E,NTNG1,GPAM,LRRC4C,PKNOX2,ARFGAP2,CAB39,NPAS3,LMO3,AJAP1,FAM168A,PRUNE2,CACNA1E,EML4,PSD3,KCNK10,REPS2,MED1,PPP2R5C,PRKACB,PTCH1,RABGAP1L,KCNK2,KIF2A,CALN1,DTNA,ABI2" MicroRNA hsa-miR-196a:mirSVR_highEffct hsa-miR-196a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.27E-16 1.77E-12 1.13E-15 1.03E-14 45 798 "SYT9,WAC,SORCS1,ERMN,FHL1,HPCAL4,ERICH3,MIER1,RUFY2,ARHGAP5,SLC14A1,ATP1A2,PALLD,DNER,RAP1GAP2,LMO3,KLHL4,ANO4,GPM6B,ACSL6,CACNA1E,CACNB2,ZEB1,PTBP2,GRIA2,OPCML,PDE3B,TMEFF2,A2ML1,BEST1,CHD1L,PPP3CB,ATRNL1,CTNND1,ANKS1B,ZNF385B,CA10,HP1BP3,SMG7,KCNJ10,FAM13C,RERGL,RAVER2,ELAVL4,EPB41L2" MicroRNA hsa-miR-191*:mirSVR_lowEffct hsa-miR-191*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-16 1.82E-12 1.16E-15 1.06E-14 38 570 "ACTN2,ECSIT,TUBB4A,AGT,FGF1,ANK1,GPAM,ST3GAL3,URGCP,MTR,WDTC1,ZSWIM8,ARPP21,NCAM1,C11orf87,ADHFE1,MYRF,GOLGB1,TCF7L2,VXN,GRIA4,LGI1,SEMA5B,CNTN1,NSD2,CNRIP1,SNCAIP,TENM4,PRKCG,TOX,PRDM2,COPS7A,SRGAP3,KCNMA1,DLG3,FAM57B,PHC2,ABI2" MicroRNA hsa-miR-196b*:mirSVR_lowEffct hsa-miR-196b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.46E-16 1.88E-12 1.19E-15 1.10E-14 37 540 "EPS8,SYT9,LDLRAD3,FHL1,DOCK10,GPAM,DGKD,CACHD1,CSPG5,LGI3,SNAP25,NEK6,TTLL9,NPAS3,C11orf87,ADHFE1,CAMTA1,CAMSAP2,ZEB1,PTBP2,GPR88,CRB1,SPX,P2RX7,PAH,JAM2,CADM1,CELF5,BTF3L4,OSBPL3,KCNA6,PTPRO,RABGAP1L,PCDH15,ABI1,DTNA,VWA5A" MicroRNA hsa-miR-1180:mirSVR_lowEffct hsa-miR-1180:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.68E-16 1.99E-12 1.27E-15 1.16E-14 36 511 "SERPINA3,MDM4,PPM1E,ST3GAL3,RPH3A,NSG2,SCMH1,CAPRIN2,SOX1,JPH4,CAMTA1,CACNB2,GPR17,VSTM2A,LINC00839,SPX,MFSD2A,P2RX7,LGI1,CHGA,PFKFB3,PLEKHB1,SEMA5B,PLXNB3,CRLS1,RGS6,ATRNL1,PLCH2,MAPK10,SYNC,KCNA1,KCNA6,KCNK1,OLIG1,SEC61A2,SEZ6" MicroRNA hsa-miR-139-5p:PITA hsa-miR-139-5p:PITA_TOP PITA 3.82E-16 2.07E-12 1.31E-15 1.21E-14 29 319 "NDRG2,SCN3A,SCN4B,LRRC7,ANK1,ATP2B2,SOX1,SOX5,ERBIN,SEPT3,PCDH11X,UNC5D,TCF12,PSD3,FBXL16,RBFOX2,ADGRG1,FAT3,NXPH1,PPP3CB,KIAA0408,TOX,MAGI2,KCNA1,SV2A,DPP6,RTN4,PAK5,ST8SIA3" MicroRNA hsa-miR-380:PITA hsa-miR-380:PITA_TOP PITA 3.95E-16 2.14E-12 1.36E-15 1.25E-14 32 398 "SNX30,LRRC7,ELMOD1,SOX6,ARHGAP5,CCDC88A,SNAP25,B3GALT2,ENKUR,CLASP2,SYT4,OPCML,KCNK10,PCDH8,CDH10,CADM1,NRXN1,ACBD5,BRINP3,LRRTM3,ITGAV,HP1BP3,KCNA4,PTPRE,DLG2,KIF2A,TMEM255A,ABI1,FAM13C,SLC6A15,SSPN,EPB41L1" MicroRNA hsa-miR-371-5p:mirSVR_highEffct hsa-miR-371-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.00E-16 2.16E-12 1.37E-15 1.26E-14 51 1017 "TMEM74,RTN3,SORCS1,LRRTM4,LINC00461,CDC42BPA,ITSN1,PKP4,SHTN1,MIER1,ASPH,SNAP25,USP33,ILDR2,LMO3,C11orf87,NEUROD1,GLS,AZIN2,PTBP2,EML4,CAMK2G,VSTM2A,GRIA1,GRIA2,GRIA4,PCDH8,SEZ6L,MAGI1,BEST3,FTO,BEST1,BTF3L4,NXPH1,MFSD4A,CRLS1,MICAL2,DZIP3,FGFR1OP2,ANKS1B,BDNF-AS,BLOC1S6,SMG7,PTPRZ1,TMEM255A,SLC25A18,RAP1GAP,RTN4,ABI2,RCAN2,UEVLD" MicroRNA hsa-miR-124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-16 2.17E-12 1.38E-15 1.26E-14 62 1446 "SDE2,F3,DSCAML1,ADD3,TMEM156,TUBB4A,FOXRED2,SCN3A,FGF1,UNC79,MOBP,MSRA,CAPRIN2,ADGRA1,PALLD,ZCCHC24,ARPP21,NEK6,ADAM15,KIF1B,NASP,DCAF5,NFIA,ROBO3,CAMTA1,UNC5D,GPM6B,NEU4,GRIA1,GRIA2,RFFL,CRB1,INA,PDE3B,IGFN1,PLEKHB1,TUB,TMEFF2,ARHGAP22,TJP2,CABP1,MICAL1,PRRX1,ETNPPL,MICAL2,RBPJ,CTNND1,ECE2,ANKS1B,TUBB2B,SYNC,BLOC1S6,PTPRZ1,CCDC3,KCNK1,KCNK2,RAB3IL1,DNM2,L1CAM,PHC2,RAVER2,ROM1" MicroRNA hsa-miR-299-5p:mirSVR_highEffct hsa-miR-299-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.20E-16 2.27E-12 1.44E-15 1.32E-14 40 637 "CSMD3,WAC,FGF14,FOXG1,ANXA7,GPAM,CCDC88A,SLC14A1,EIF4G3,PHYHIPL,CAB39,KIF1B,GLS,DDHD2,CAMSAP2,CLEC9A,CECR2,GRIA4,PCDH8,CDH10,TPD52,PDE3B,NLGN3,NRXN1,SULT4A1,CNTN1,SLC36A4,CHD1L,SF1,RBPJ,USP54,NRSN1,LRRTM3,SIRPA,BLOC1S6,PTPRD,DLG2,RFX5,FAM135B,EN2" MicroRNA hsa-miR-412:mirSVR_highEffct hsa-miR-412:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-16 2.37E-12 1.50E-15 1.38E-14 42 703 "RABEPK,EPS8,ZFYVE27,MDM4,CDC7,SOX6,SFPQ,ASRGL1,PPFIA1,PKP4,NLGN1,SHTN1,PDE8B,MTR,SORCS3,SMARCE1,WDTC1,TTLL9,NAP1L2,NPAS3,NASP,NCAM1,ZNF638,KLHL4,TBX15,VSTM2A,GRIK2,TF,MFSD2A,TMEM257,CDH10,GDAP1L1,A2ML1,ACBD5,MFSD4A,SNCAIP,ATRNL1,PRKCZ,NTM,RABGAP1L,PCDH15,ELAVL3" MicroRNA hsa-miR-202*:mirSVR_highEffct hsa-miR-202*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.75E-16 2.57E-12 1.63E-15 1.49E-14 43 738 "PRR5L,RTN3,KLHL32,ERMN,LRRTM4,DISP3,PKP4,NTNG1,CCDC88A,SPHKAP,MYT1L,CAB39,NFASC,ZNF302,ERBIN,CAMSAP2,GPM6B,ZEB1,TCF12,CECR2,INA,TJP1,TMEFF2,PRRX1,MED1,CRLS1,PPP2R5C,SNCAIP,FEZ1,ATRNL1,PLCH2,USP54,HES5,PRDM2,CEP170,KCNA4,C1orf109,PTPRZ1,KCNK1,SLC17A6,ABI1,FAM13C,VANGL2" MicroRNA hsa-miR-4312:mirSVR_highEffct hsa-miR-4312:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.98E-16 2.69E-12 1.71E-15 1.56E-14 36 516 "PAQR6,WLS,SCN3A,PPFIA1,BCAS1,PAAF1,ZNF365,MIER1,SLC8A3,KIF1B,ERBIN,ADHFE1,ZNF638,NODAL,ANO4,GRIA2,GRIA4,PLXNB3,CNRIP1,CP,CHD1L,NCAN,PRKACB,CTNND2,NRSN1,SYTL2,ANKS1B,CNIH3,BLOC1S6,OLFM3,KCNJ11,PLEKHB2,FAM13C,NUP214,RET,SLC4A10" MicroRNA hsa-miR-142-3p:mirSVR_highEffct hsa-miR-142-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.00E-16 2.71E-12 1.71E-15 1.57E-14 44 773 "CNTNAP3,LGR4,ECSIT,ANK3,USP28,APC,NTNG1,CCDC88A,ATP1A2,PHYHIPL,USP33,SOX5,SPART,OS9,GNAS,PSRC1,ADGRL3,CACNA1E,PRLHR,EML4,GRIA4,PAX6,PRMT8,PDE4B,HMGB1,TLX1,A2ML1,SLC25A27,BEST1,NSD2,CP,FEZ2,PRKAB2,RAB39A,PUM1,ITGAV,COPS7A,CCDC3,DLG2,ATG16L1,PAK5,ZYG11B,SSPN,RCAN2" MicroRNA hsa-miR-1267:mirSVR_highEffct hsa-miR-1267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.25E-16 2.85E-12 1.80E-15 1.65E-14 51 1024 "ADGRV1,ERMN,AMPH,ERICH3,ITSN1,PKP4,APC,NTNG1,BCAN,ST3GAL3,RUFY2,MSR1,ARHGAP5,CCDC88A,RCOR3,NRG3,USP33,MYT1L,NPAS3,ZNF302,AJAP1,SYT4,TCF7L2,GRIA1,GRIK3,TLL2,CELF3,PC,JAM2,NXPH1,MFSD4A,CP,MAPK8,PUM1,ANKS1B,PLPPR5,PSMD13,PLPPR1,PRDM2,LRP8,PTPRE,PTPRO,KCNMA1,SNX27,CAB39L,FAM13C,DBX2,INSYN2,RPRD1A,OLIG2,EPB41L2" MicroRNA hsa-miR-22:mirSVR_highEffct hsa-miR-22:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.46E-16 2.95E-12 1.87E-15 1.71E-14 40 642 "ACER3,RTN3,GRAMD1B,TOMM40L,AMPH,ITSN1,NTNG1,CCDC80,TACC2,RUFY2,ATM,CCDC181,TTLL9,KIF1B,DNER,NPAS3,NDUFA5,KIRREL3,ADHFE1,ZNF638,CAMSAP2,VXN,AIFM1,MAEL,PDE1A,CHGA,DUSP26,GDAP1L1,CADM1,MFSD4A,VCAN,PLPPR1,MAGI2,OLFM3,RAB5B,TMEM255A,CAMK1G,ZNF248,ABI2,EPB41L2" MicroRNA hsa-miR-185:PITA hsa-miR-185:PITA_TOP PITA 5.64E-16 3.05E-12 1.93E-15 1.77E-14 24 207 "ASIC1,ARID1A,ARHGAP5,SNAP25,ATP1A3,SOX5,NMNAT2,TCF12,RFFL,TJP1,CDC42,PCDH9,CCSER2,NSD2,SF1,CA10,HP1BP3,SMG7,KCNN3,DLG2,PAK5,GPR61,ELAVL3,RCAN2" MicroRNA hsa-miR-31:PITA hsa-miR-31:PITA_TOP PITA 5.83E-16 3.16E-12 1.99E-15 1.83E-14 25 229 "ARID1A,TESK2,ELMOD1,TACC2,SLC1A2,AHCYL1,CLASP2,CACNB2,TCF12,CAMK2G,SYT6,PC,TNS1,ZNF384,FNDC5,GDAP1L1,TENM4,CTNND2,RIMS3,SYNC,SRGAP3,PEX5,RTN4,FAM135B,RBM12" MicroRNA hsa-miR-98:mirSVR_highEffct hsa-miR-98:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.89E-16 3.19E-12 2.01E-15 1.85E-14 45 811 "LGR4,ARID1A,MDM4,KLHL32,ERMN,SESN3,PAAF1,GABBR1,CAB39,AHCYL1,KIF1B,DNER,CLASP2,ADHFE1,GANAB,ACSL6,CACNB2,GRIA2,ADAMTS8,GPR88,CRB1,TGFBR3,AIFM1,PDE3B,SLC25A27,BEST1,PRRX1,MFSD4A,OSBPL3,IGSF1,MASP1,SYNC,PRDM2,PTPRO,KCNJ11,KCNK1,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-1206:mirSVR_highEffct hsa-miR-1206:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.90E-16 3.20E-12 2.01E-15 1.85E-14 51 1027 "KLHL32,DSCAML1,ADD3,SCN3A,LRRC7,SEMA6A,BBOX1,PPFIA1,APC,SHTN1,MT3,NSG2,SMARCE1,ADGRA1,KIF21B,TTLL9,CLASP2,ZNF302,HEPN1,CAMSAP2,ADGRL3,CACNA1E,LRIT2,CACNB2,NUMA1,GRIA2,SPX,MFSD2A,TLL2,PCDH9,CDH10,ZMYND8,GDAP1L1,CADM1,ANLN,PPP3CB,KCNT2,PHACTR3,PKN2,PRKCZ,PUM1,BRINP3,HP1BP3,NTM,BSDC1,PHC2,SEC61A2,VWA5A,YY1AP1,EPB41,EPB41L2" MicroRNA hsa-miR-335:PITA hsa-miR-335:PITA_TOP PITA 6.18E-16 3.34E-12 2.11E-15 1.93E-14 23 187 "CDC7,SORCS1,PPM1E,ZSWIM8,NMNAT2,BCL2L2,CAMTA1,PSD3,TMEM257,PCDH9,RBFOX2,NRXN1,FAT3,NXPH1,POU3F2,PPP2R5C,OSBPL3,MAPK10,FAM131B,GOPC,RBM12,ARHGAP12,ELAVL3" MicroRNA hsa-miR-423-5p:mirSVR_highEffct hsa-miR-423-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.20E-16 3.36E-12 2.11E-15 1.94E-14 41 677 "TTYH1,ACLY,DUSP27,ARID1A,RTKN,MDM4,ERMN,FCGR1A,FOXM1,TRIM46,SELL,ITSN1,BCO1,MT3,SLC14A1,CGREF1,TAGLN3,B4GALNT1,ADAM15,C11orf87,RGL1,TCF12,RFFL,USP2,INA,CDC42,PDYN,FADS2,SLC25A27,FEZ1,MICAL2,ECE2,SYNC,CNIH3,MAGI2,KCNC1,TMCC2,PYGM,ATN1,EFNA3,YY1AP1" MicroRNA hsa-miR-4312:mirSVR_lowEffct hsa-miR-4312:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.23E-16 3.92E-12 2.46E-15 2.26E-14 54 1146 "PRR5L,CDHR1,EMID1,ACTN2,CSMD2,SORCS1,GRAMD1B,TUBB4A,FCGR1A,TOMM40L,LRRC7,SEMA6A,FHL1,HPCAL4,ANK1,SORBS1,SCG3,SLCO1A2,EIF4G3,SEMA4A,GNG3,TMEM136,CACNA1E,TCF7L2,TCF12,PCDHGA3,VXN,VSTM2A,P2RX7,CDC42,CDH8,TPD52,PDE1A,PRMT8,FNDC5,ZFYVE9,TJP2,PMP2,SLC25A27,BEST1,PPP2R5C,TENM4,CMTM5,KIAA0408,PTHLH,KCNA6,NTM,PCDH15,TMEM255A,SLC25A41,GOPC,SSPN,RBM12,ELAVL4" MicroRNA hsa-miR-3146:mirSVR_highEffct hsa-miR-3146:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.57E-16 4.10E-12 2.58E-15 2.36E-14 41 681 "ADD3,GPR158,SFPQ,APC,MIER1,SLC1A6,RUFY2,NSG2,PHYHIPL,PALLD,ARPP21,COLGALT2,SLCO1C1,UNC5D,ADGRL3,ZEB1,TCF12,NUMA1,ZFP91,REPS2,MAGI1,TMEFF2,ZFYVE9,TJP2,MFSD4A,KCNT2,DPYSL5,PLPPR1,BDNF-AS,HP1BP3,OLFM3,KCNC1,NTM,KCNK2,DNAH9,KLRC2,TMEM255A,DTNA,ABCC9,RPRD1A,RAVER2" MicroRNA hsa-miR-1324:PITA hsa-miR-1324:PITA_TOP PITA 7.96E-16 4.31E-12 2.71E-15 2.48E-14 29 328 "MAG,EPS8,ASIC1,MAPT,WAC,NLGN4X,LRRTM4,SEMA6A,APBB1,CSPG5,SNCB,ATP2B2,MYT1L,ZSWIM8,NCAM1,CDK5R2,CAMK2A,PTPN5,FBXL16,PCDH8,MAGI1,PDE1C,FNDC5,NXPH1,SIRPA,CEP170,SLC17A6,DSCAM,FAM135B" MicroRNA hsa-miR-148b*:mirSVR_highEffct hsa-miR-148b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.06E-16 4.36E-12 2.74E-15 2.51E-14 54 1149 "CNTNAP3,SYT9,EYA1,LDLRAD3,MDM4,WAC,AMER2,FCGR1B,FHL1,ELMOD1,CNIH2,APC,MAGI3,SORBS1,NLGN1,MIER1,RUFY2,SPHKAP,SMARCE1,TTLL9,DNER,AJAP1,ACSBG1,DDHD2,ACSL6,ZEB1,TCF12,PTBP2,EML4,TMEM25,LEFTY2,GUCY1A2,DLGAP3,A2ML1,MEAF6,P2RY12,SNCAIP,MICAL2,DOCK7,PUM1,PTPRD,SMG7,RABGAP1L,KCNMA1,ATG16L1,ABI1,FAM13C,DBX2,FAM135B,SYT15,SEC61A2,LPAR6,SLC4A10,BAALC" MicroRNA hsa-miR-381:PITA hsa-miR-381:PITA_TOP PITA 8.50E-16 4.60E-12 2.88E-15 2.65E-14 36 525 "EPS8,SNX30,GPR158,SFPQ,CDC42BPA,ANK3,PPM1E,DGKD,SORBS1,SLC1A2,EIF4G3,NAP1L2,GFRA1,NEUROD1,NFIA,VAMP1,PCDH11X,POPDC3,ANO4,CACNB2,PCDH8,PCSK2,NRXN1,PRRX1,ACBD5,OSBPL3,RBPJ,PTCH1,ZC3H11A,KCNA4,SNX27,DPP6,ST8SIA3,FAM135B,EPB41,EPB41L1" MicroRNA hsa-miR-300:PITA hsa-miR-300:PITA_TOP PITA 8.50E-16 4.60E-12 2.88E-15 2.65E-14 36 525 "EPS8,SNX30,GPR158,SFPQ,CDC42BPA,ANK3,PPM1E,DGKD,SORBS1,SLC1A2,EIF4G3,NAP1L2,GFRA1,NEUROD1,NFIA,VAMP1,PCDH11X,POPDC3,ANO4,CACNB2,PCDH8,PCSK2,NRXN1,PRRX1,ACBD5,OSBPL3,RBPJ,PTCH1,ZC3H11A,KCNA4,SNX27,DPP6,ST8SIA3,FAM135B,EPB41,EPB41L1" MicroRNA hsa-miR-3198:mirSVR_highEffct hsa-miR-3198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.68E-16 4.70E-12 2.95E-15 2.70E-14 40 651 "DUSP27,ATAT1,FABP7,ERMN,TUBB4A,ELMOD1,FOXM1,PKP4,APC,ST3GAL3,RUFY2,ASPH,SNAP25,SOX1,B3GALT2,ILDR2,ROBO3,CAMTA1,TBX15,GRIA2,GRIA4,CRB1,LGI1,PCSK2,CHGA,JAM2,P2RY12,SNCAIP,RGS6,VCAN,PLPP4,USP54,DNAJC6,WIPF2,DNM2,SLC25A18,SUSD4,DTNA,RFX4,RGS7" MicroRNA hsa-miR-3135:mirSVR_lowEffct hsa-miR-3135:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.72E-16 4.72E-12 2.96E-15 2.71E-14 49 963 "PAQR6,FCGR1A,BCAR3,APBB1,MAGI3,BCAS1,MIER1,KIAA1614,CADPS,ASTN1,RCOR3,ALDH4A1,ATM,PALLD,WDTC1,NDUFA5,DCAF5,ACSL6,TF,LEFTY2,P2RX7,TNFRSF1B,HPS5,PTGDR2,HRH3,MAGI1,BEST3,CAMKV,SEMA5B,A2ML1,FTO,CRLS1,MICAL2,PRKACB,CMTM5,SIRPA,BDNF-AS,PTHLH,KCNA1,KCNK2,DPP6,SLC25A41,GNE,ABCC9,RGR,FAM135B,EEF1A2,VANGL2,LRRC23" MicroRNA hsa-miR-186-5p:TargetScan hsa-miR-186-5p TargetScan 9.24E-16 5.00E-12 3.13E-15 2.87E-14 41 685 "BCAR3,CDC42BPA,ANK3,CCDC80,MIER1,KIAA1614,ARHGAP5,NSG2,CADPS,BRINP2,ATP1A2,MYT1L,NASP,LMO3,GFRA1,FAM168A,ACSBG1,KAZN,BTRC,DDR2,PSD3,GRIA2,CELF3,CDC42,RBFOX2,PDE3B,HMGB1,ARHGAP22,CADM1,NEGR1,FTO,NXPH1,OSBPL3,KIAA0408,LRRTM3,PMEPA1,CADM2,CAB39L,PID1,ATL1,ABI2" MicroRNA hsa-miR-129-1-3p:TargetScan hsa-miR-129-1-3p TargetScan 1.00E-15 5.44E-12 3.40E-15 3.12E-14 30 357 "MAPT,GRAMD1B,AMER2,ARFGAP2,SCN3B,ILDR2,AHCYL1,NMNAT2,JPH4,BCL2L2,NFIA,CAMSAP2,MYRF,CNTN2,GPM6B,CACNA1E,GUCY1A2,FNDC5,FTO,MED1,MAPK10,RIMS3,NAV2,DLG2,RAB5B,CALN1,FAM135B,ELAVL3,RCAN2,BAALC" MicroRNA hsa-miR-129-2-3p:TargetScan hsa-miR-129-2-3p TargetScan 1.00E-15 5.44E-12 3.40E-15 3.12E-14 30 357 "MAPT,GRAMD1B,AMER2,ARFGAP2,SCN3B,ILDR2,AHCYL1,NMNAT2,JPH4,BCL2L2,NFIA,CAMSAP2,MYRF,CNTN2,GPM6B,CACNA1E,GUCY1A2,FNDC5,FTO,MED1,MAPK10,RIMS3,NAV2,DLG2,RAB5B,CALN1,FAM135B,ELAVL3,RCAN2,BAALC" MicroRNA hsa-miR-197:mirSVR_highEffct hsa-miR-197:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-15 5.48E-12 3.42E-15 3.14E-14 40 654 "RBM10,EYA1,FCGR1A,ITSN1,PKP4,ZCCHC17,NLGN1,ST3GAL3,SLC2A5,CCDC88A,NAXD,CAPRIN2,IDI2-AS1,NCAM1,ZNF302,NELL1,SYT4,NKX2-2,GOLGB1,CECR2,GRIA2,GRIN1,INA,PDE3B,PRMT8,MEAF6,POU3F2,SNCAIP,PRKCZ,CTNND1,FGFR1OP2,GON4L,RAB5B,KLRC2,SUSD4,RGR,ARHGEF10L,PIANP,RPRD1A,EPB41" MicroRNA hsa-miR-653:PITA hsa-miR-653:PITA_TOP PITA 1.04E-15 5.63E-12 3.52E-15 3.23E-14 28 306 "EPS8,ARID1A,SLITRK1,ADD3,SCN3A,CDC42BPA,CCDC88A,DACH2,RCOR3,PHYHIPL,SON,B3GALT2,SOX5,CAB39,NCAM1,RCOR2,NEUROD1,NFIA,POPDC3,GPM6A,GRIA1,REPS2,UBTF,SF1,CADM2,OCIAD1,PTPRZ1,DLG2" MicroRNA hsa-miR-132-3p:TargetScan hsa-miR-132-3p TargetScan 1.17E-15 6.32E-12 3.94E-15 3.61E-14 30 359 "MAPT,ARID1A,SCN3A,CDC42BPA,NTNG1,RPH3A,ARFGAP2,CCDC88A,DKK3,KIF21B,NMNAT2,SALL3,C11orf87,NFIA,CAMSAP2,PTBP2,GRM3,CDH8,GPR37L1,NMT2,PPP2R5C,LRRTM3,PTCH1,CSDE1,PTPRD,KCNA6,KCNK2,KCNN3,KIF2A,RBM12" MicroRNA hsa-miR-212-3p:TargetScan hsa-miR-212-3p TargetScan 1.17E-15 6.32E-12 3.94E-15 3.61E-14 30 359 "MAPT,ARID1A,SCN3A,CDC42BPA,NTNG1,RPH3A,ARFGAP2,CCDC88A,DKK3,KIF21B,NMNAT2,SALL3,C11orf87,NFIA,CAMSAP2,PTBP2,GRM3,CDH8,GPR37L1,NMT2,PPP2R5C,LRRTM3,PTCH1,CSDE1,PTPRD,KCNA6,KCNK2,KCNN3,KIF2A,RBM12" MicroRNA hsa-miR-500*:mirSVR_highEffct hsa-miR-500*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-15 6.49E-12 4.04E-15 3.71E-14 38 593 "SLC25A25,NDRG2,CLIP1,ELMOD1,FOXG1,TACC2,JAKMIP3,NSG2,ARPP21,TTLL9,IDI2-AS1,ACSBG1,ZNF638,DDHD2,CAMSAP2,GPM6A,DDR1,GPR17,CAMK2G,GRIK2,MAEL,CADM1,BTF3L4,RNF14,PHACTR3,RBPJ,USP54,PLPPR1,BDNF-AS,PLPPR4,DLG2,RALGDS,PAK5,ABCC9,JMJD1C,ATL1,RPRD1A,UEVLD" MicroRNA hsa-miR-491-5p:mirSVR_highEffct hsa-miR-491-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.40E-15 7.57E-12 4.72E-15 4.33E-14 42 727 "ASIC1,ARID1A,MDM4,SCN4B,ACTL6B,MOG,SGIP1,PI16,SH3GL2,SLC1A7,SLC8A3,SORCS3,ATP2B2,WDTC1,MYT1L,NFASC,BCL2L2,DIRAS1,INA,CELF3,PRMT8,PLEKHB1,TJP2,CP,PNKD,KCNT2,MICAL2,RBPJ,PRKCG,IGSF1,PUM1,DNAJC6,KCNA6,KCND3,KCNMA1,PYGM,ATN1,RASGRF1,NUP214,PHC2,SEC61A2,EPB41L1" MicroRNA hsa-miR-634:mirSVR_highEffct hsa-miR-634:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-15 7.81E-12 4.86E-15 4.46E-14 40 661 "ZFYVE27,RTN1,SLITRK1,ERMN,PLA2G6,NTNG1,ASPH,PALLD,DKK3,ARPP21,TTLL9,NPAS3,NASP,NCAM1,LMO3,CLASP2,DCAF5,ADHFE1,NEUROD1,MMD2,TMEM136,DDR1,NUDT21,SYT6,GRIA2,GRIA4,CCKBR,TGFBR3,CADM1,CCSER2,MEAF6,MED1,FEZ2,KCNJ11,KCNK2,DLG2,ZYG11B,SEC61A2,RNF220,EPB41L1" MicroRNA hsa-miR-509-3-5p:mirSVR_highEffct hsa-miR-509-3-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-15 7.83E-12 4.87E-15 4.47E-14 48 939 "ACLY,CNTNAP3,CSMD2,MDM4,TOMM40L,LRRC7,ASIC4,FHL1,ITSN1,SH3GL2,ZCCHC17,NLGN1,RCOR3,SNAP25,USP33,B3GALT2,CLASP2,ARHGEF7,PCDH11X,GPM6B,ZEB1,NRDC,NRGN,PTBP2,GRIA2,GRIA4,INA,TLL2,PCDH8,LINC01102,HMGB1,ANO5,TMEFF2,CCSER2,CNTN1,SF1,PPP3CB,PHACTR3,PRKACB,FMN2,CTNND1,PTPRD,PTPRE,PTPRZ1,SNX27,NKAIN1,HS3ST4,UEVLD" MicroRNA hsa-miR-154:PITA hsa-miR-154:PITA_TOP PITA 1.75E-15 9.46E-12 5.88E-15 5.39E-14 23 196 "RTN3,WAC,ANK3,PPM1E,SLC1A2,PKNOX2,TMEM108,B4GALNT1,NFIA,SYT4,LUZP2,TCF12,CAMK2G,FBXL16,NEGR1,PRRX1,MED1,CADM2,MAGI2,RAB5B,TMEM255A,ABI1,RBM12" MicroRNA hsa-miR-216b:PITA hsa-miR-216b:PITA_TOP PITA 1.75E-15 9.48E-12 5.89E-15 5.40E-14 29 338 "SLITRK1,SNX30,PKP4,NTNG1,SLC1A2,SPHKAP,SOX5,SMOC1,ERBIN,NFIA,GPM6A,GPR19,EML4,VXN,PFKFB3,VAV2,PMP2,FAT3,PPP3CB,KCNT2,CHD5,PRKAB2,FAM131B,HP1BP3,OLFM3,PEX5,INSYN2,ELAVL3,EPB41" MicroRNA hsa-miR-3126-3p:mirSVR_highEffct hsa-miR-3126-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-15 9.87E-12 6.13E-15 5.62E-14 39 633 "ZFYVE27,TMEM74,MEG3,ARID1A,RTKN,KCNIP2,FOXG1,ITSN1,SLITRK3,TMEM108,ATM,USP33,CAB39,ARHGEF7,CASTOR3,SYT4,DDHD2,MMD2,GPM6B,CACNA1E,TCF12,GRIA4,SEZ6L,LGI1,PDE1A,PRMT8,SLC25A27,NCAN,MASP1,WBP1L,CA10,PRDM2,PEX5,KIF2A,DTNA,SLC6A15,JMJD1C,ELAVL4,EPB41L2" MicroRNA hsa-miR-1277:mirSVR_highEffct hsa-miR-1277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-15 1.01E-11 6.25E-15 5.74E-14 33 449 "MBP,HOGA1,FHL1,ELMOD1,MOBP,SH3GL2,APBA2,SHTN1,CAPRIN2,SORCS3,SMARCE1,RCOR3,NEK6,PCDH11X,LUZP2,DDHD2,CAMSAP2,GOLGB1,ACSL6,LRIT2,PAX6,PCDH9,TPD52,MAGI1,CASC2,PIK3CD,MEAF6,IGSF1,EDRF1,PMEPA1,HP1BP3,BLOC1S6,RFX5" MicroRNA "CATTTCA,MIR-203:MSigDB" "CATTTCA,MIR-203:MSigDB" MSigDB 1.88E-15 1.02E-11 6.30E-15 5.78E-14 26 264 "ARID1A,FOXG1,APC,DGKZ,API5,SLC1A2,SLC7A14,YPEL4,ATM,ATP2B2,CAB39,NMNAT2,CLASP2,SEPT3,TCF12,CDH10,PCSK2,MAGI1,NEGR1,NXPH1,SPIRE1,SLC17A6,C12orf4,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-645:mirSVR_lowEffct hsa-miR-645:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-15 1.03E-11 6.37E-15 5.84E-14 50 1020 "SERPINA3,GALNT13,HOGA1,TESK2,PLA2G6,ANXA7,PPM1E,APC,ST3GAL3,BCAS1,MIER1,SLC8A2,DACH2,CADPS,ATM,ZSWIM8,SPART,COLGALT2,INKA2,ADHFE1,NEUROD1,NFIA,POPDC3,PRUNE2,LRIT2,GRID1,OPCML,MFSD2A,INA,ZFP91,TNFRSF1B,CASC2,CCSER2,FAM181B,PMP2,MEAF6,ATCAY,CNRIP1,MED1,SNCAIP,MAPK10,PLPPR5,SHD,KCNJ10,SLC25A18,BSDC1,SH3GLB1,YY1AP1,PRRT4,EPB41" MicroRNA hsa-miR-4728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-15 1.05E-11 6.47E-15 5.94E-14 45 838 "EMID1,ADAR,WAC,CCDC80,JAKMIP3,CLSTN1,SLC1A2,PKNOX2,DNAH17,ASPH,KBTBD12,ZCCHC24,NKX6-2,TTLL9,ADGRB2,NDUFA5,GNG4,NRGN,HAP1,CAMK2A,PADI2,BEST3,SCRG1,TMPRSS5,PFKFB3,DLGAP3,CCSER2,BTF3L4,FAT3,MFSD4A,PTPA,DOCK7,DPYSL5,PHYHIP,TOMM20,BDNF-AS,PTPRE,NAV2,SNX27,DNAH9,RAB5B,PLEKHB2,PARP11,PHC2,ABI2" MicroRNA hsa-miR-1263:mirSVR_lowEffct hsa-miR-1263:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.95E-15 1.06E-11 6.55E-15 6.00E-14 47 910 "CSMD2,RTN1,ERMN,HOGA1,LRRTM4,SLC30A10,SFPQ,RUFY2,ARHGAP5,ADGRA1,SON,KIF21B,ARPP21,ALDH1L1,ACSL6,MFSD2A,GUCY1A2,TLL2,PCDH9,LGI1,ADGRG1,LRTM2,ASIC3,CHRNB2,ARHGAP22,PPP2R5C,RBPJ,PRKACB,DOCK7,MAPK10,TOX,WBP1L,TOMM20,PTHLH,LRP8,MAGI2,KCNA1,PLPPR4,PTPRO,KCNJ10,KCNK2,PCDH15,SLC17A6,ABI1,RFX4,JMJD1C,INSYN2" MicroRNA hsa-miR-4270:mirSVR_highEffct hsa-miR-4270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-15 1.09E-11 6.75E-15 6.19E-14 45 839 "ACER3,RTN3,RTKN,KCNIP2,GPR158,LRRC7,ERICH3,ITSN1,BCAN,ST3GAL3,PKNOX2,CCDC88A,CGREF1,KBTBD12,SNAP25,TNIK,CADM3,RAP1GAP2,STOX1,GFAP,ROBO3,ZEB1,OMG,SEZ6L,PCSK2,MAGI1,BEST3,KIAA1549L,NRXN1,CAMKV,DNAJC12,BTF3L4,MED1,RBPJ,PRKCG,ECE2,KLK6,CEP170,OLFM3,TMCC2,DLG2,DPP6,DBX2,SYT15,VWA5A" MicroRNA hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA_TOP PITA 2.07E-15 1.12E-11 6.92E-15 6.35E-14 32 422 "ARID1A,SGIP1,ANK3,SORBS1,API5,YPEL4,ASTN1,KIF21B,GAD2,CPLX2,SYT4,TBX15,GPM6A,GRID1,REPS2,CHGA,NRXN1,NEGR1,PRRX1,PACSIN1,NXPH1,PROX1,CEP170,MAGI2,ZC3H11A,PTPRD,SMG7,PEX5,DLG2,HS3ST4,PHC2,RNF220" MicroRNA hsa-miR-376a*:mirSVR_highEffct hsa-miR-376a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.16E-15 1.17E-11 7.22E-15 6.62E-14 49 986 "RABEPK,MAP6,CLIP1,SLITRK1,GALNT13,ADD3,LINC00461,PPFIA1,GPAM,RUFY2,MSR1,ARHGAP5,SMARCE1,NRG3,MEGF11,B4GALNT1,DNER,SPART,DDHD2,CAMSAP2,ADGRL3,PRUNE2,CACNB2,ZEB1,TCF12,PTBP2,LINC00839,MFSD2A,ZFP91,ARHGAP19,ZMYND8,CASC2,TMEFF2,COL9A2,FEZ1,RBPJ,USP54,ANKS1B,SYNC,PLPPR1,PTHLH,CEP170,KCNK1,SLC17A6,RASGRF1,GNE,DTNA,RTN4,BAALC" MicroRNA "CACTGTG,MIR-128B:MSigDB" "CACTGTG,MIR-128B:MSigDB" MSigDB 2.18E-15 1.18E-11 7.28E-15 6.68E-14 28 315 "SYNDIG1,ARID1A,ADCY2,PPM1E,APBA2,GPAM,CCDC88A,MEGF11,WDTC1,GAD2,ARPP21,C11orf87,NEUROD1,SEPT3,SYT4,UNC5D,DIRAS1,PTPN5,TMEM25,KCNK10,CABP1,RGS6,RIMS3,CA10,ELMO1,SV2A,VANGL2,ARHGAP12" MicroRNA "CACTGTG,MIR-128A:MSigDB" "CACTGTG,MIR-128A:MSigDB" MSigDB 2.18E-15 1.18E-11 7.28E-15 6.68E-14 28 315 "SYNDIG1,ARID1A,ADCY2,PPM1E,APBA2,GPAM,CCDC88A,MEGF11,WDTC1,GAD2,ARPP21,C11orf87,NEUROD1,SEPT3,SYT4,UNC5D,DIRAS1,PTPN5,TMEM25,KCNK10,CABP1,RGS6,RIMS3,CA10,ELMO1,SV2A,VANGL2,ARHGAP12" MicroRNA hsa-miR-4753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-15 1.39E-11 8.55E-15 7.84E-14 28 317 "FAM43B,NLGN4X,FGF1,CDC42BPA,DGKD,ASCL1,IGSF9B,MYBPC1,GFRA1,CAMK2G,TGFBR3,FBXL16,P2RX7,TNS1,GDAP1L1,NEGR1,FAM181B,PNKD,RIMS4,RIMS3,CADM2,ZC3H11A,KCNK2,NAV2,SH3GLB1,ABI2,CBLN2,ELAVL3" MicroRNA hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 2.59E-15 1.40E-11 8.63E-15 7.92E-14 25 244 "SCN3A,ANK1,ANK3,ITSN1,ANXA7,CCDC88A,MYT1L,LHFPL4,NPAS3,NFASC,CLASP2,BCL2L2,BTRC,CAMK2G,HNRNPK,CADM1,ATCAY,MED1,IGSF1,CADM2,KCNA6,INSYN2,RPRD1A,GPR61,ELAVL3" MicroRNA hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 2.59E-15 1.40E-11 8.63E-15 7.92E-14 25 244 "SCN3A,ANK1,ANK3,ITSN1,ANXA7,CCDC88A,MYT1L,LHFPL4,NPAS3,NFASC,CLASP2,BCL2L2,BTRC,CAMK2G,HNRNPK,CADM1,ATCAY,MED1,IGSF1,CADM2,KCNA6,INSYN2,RPRD1A,GPR61,ELAVL3" MicroRNA hsa-miR-631:mirSVR_lowEffct hsa-miR-631:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.68E-15 1.45E-11 8.92E-15 8.19E-14 53 1144 "KCNIP2,DRAXIN,TOMM40L,TESK2,FOXG1,ANK1,ITSN1,MAGI3,ZNF365,SLC8A3,TAGLN3,NCAM1,CLASP2,HEPN1,ARHGEF7,MMD2,DDR1,PTBP2,PCDHGA3,NUMA1,CYB561A3,CRB1,TNFRSF1B,PC,TPD52,IGFN1,PIRT,LINC01102,ZMYND8,CASC2,CHRNB2,SEMA5B,NMT2,BEST1,CHD1L,PPP2R5C,NCAN,RBPJ,FAM131B,MASP1,WBP1L,PHYHIP,PLPPR5,ZNF385B,C1orf109,KCNJ9,NKAIN1,RAB5B,DNM2,ATN1,RPRD1A,ELAVL3,PRRT4" MicroRNA hsa-miR-3151:mirSVR_highEffct hsa-miR-3151:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.68E-15 1.45E-11 8.92E-15 8.19E-14 36 545 "RTN3,SNX32,BCAN,CACHD1,JAKMIP3,URGCP,MADD,GANAB,SEPT3,SLCO1C1,VAMP1,CAMTA1,HAP1,CAMK2G,CECR2,MFSD2A,TIE1,AIFM1,SEZ6L,TPM4,ZMYND8,CHGA,CADM1,KIAA1549L,BEST1,PNKD,CRMP1,PRKAB2,PKN2,KCNA2,PYGM,HS3ST4,CAMK1G,USH1C,RFX4,SEC61A2" MicroRNA hsa-miR-215:mirSVR_lowEffct hsa-miR-215:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-15 1.48E-11 9.10E-15 8.35E-14 48 955 "SDE2,SYT9,MRVI1,KLHL32,TOMM40L,FOXG1,ARFGAP2,ASPH,SLN,B3GAT1,ATP1A2,NMNAT2,ENKUR,KIF1B,SPART,NCAM1,CAMTA1,GNG3,PTBP2,EML4,SYT6,GRIA1,CRB1,INA,AIFM1,HRH3,ARHGAP19,TUB,CAMKV,CPT1C,PMP2,BEST1,MICAL2,VCAN,PRKACB,NOS1AP,SYTL2,ANKS1B,CA10,JAKMIP2,COPS7A,BLOC1S6,KCNA1,KCNA2,PTPRE,DLG3,PAK5,ABI2" MicroRNA hsa-miR-192:mirSVR_lowEffct hsa-miR-192:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-15 1.48E-11 9.10E-15 8.35E-14 48 955 "SDE2,SYT9,MRVI1,KLHL32,TOMM40L,FOXG1,ARFGAP2,ASPH,SLN,B3GAT1,ATP1A2,NMNAT2,ENKUR,KIF1B,SPART,NCAM1,CAMTA1,GNG3,PTBP2,EML4,SYT6,GRIA1,CRB1,INA,AIFM1,HRH3,ARHGAP19,TUB,CAMKV,CPT1C,PMP2,BEST1,MICAL2,VCAN,PRKACB,NOS1AP,SYTL2,ANKS1B,CA10,JAKMIP2,COPS7A,BLOC1S6,KCNA1,KCNA2,PTPRE,DLG3,PAK5,ABI2" MicroRNA hsa-miR-148b-3p:TargetScan hsa-miR-148b-3p TargetScan 2.79E-15 1.51E-11 9.25E-15 8.48E-14 37 577 "PRR5L,ACHE,MDM4,F3,ADCY2,GRAMD1B,ANK2,MIER1,ASPH,NCAM1,BCL2L2,NEUROD1,CAMSAP2,GPM6A,CAMK2A,RBFOX2,PDE4B,CHRNB2,CADM1,BEST1,POU3F2,MED1,FEZ2,DPYSL5,ELMO1,LRP8,RGMA,CDH20,PTPRD,KCND3,KCNH1,KCNN3,DLG2,RTN4,JMJD1C,ELAVL4,EPB41L1" MicroRNA hsa-miR-148a-3p:TargetScan hsa-miR-148a-3p TargetScan 2.79E-15 1.51E-11 9.25E-15 8.48E-14 37 577 "PRR5L,ACHE,MDM4,F3,ADCY2,GRAMD1B,ANK2,MIER1,ASPH,NCAM1,BCL2L2,NEUROD1,CAMSAP2,GPM6A,CAMK2A,RBFOX2,PDE4B,CHRNB2,CADM1,BEST1,POU3F2,MED1,FEZ2,DPYSL5,ELMO1,LRP8,RGMA,CDH20,PTPRD,KCND3,KCNH1,KCNN3,DLG2,RTN4,JMJD1C,ELAVL4,EPB41L1" MicroRNA hsa-miR-152-3p:TargetScan hsa-miR-152-3p TargetScan 2.79E-15 1.51E-11 9.25E-15 8.48E-14 37 577 "PRR5L,ACHE,MDM4,F3,ADCY2,GRAMD1B,ANK2,MIER1,ASPH,NCAM1,BCL2L2,NEUROD1,CAMSAP2,GPM6A,CAMK2A,RBFOX2,PDE4B,CHRNB2,CADM1,BEST1,POU3F2,MED1,FEZ2,DPYSL5,ELMO1,LRP8,RGMA,CDH20,PTPRD,KCND3,KCNH1,KCNN3,DLG2,RTN4,JMJD1C,ELAVL4,EPB41L1" MicroRNA hsa-miR-1252:PITA hsa-miR-1252:PITA_TOP PITA 2.82E-15 1.53E-11 9.35E-15 8.58E-14 30 371 "WAC,SEMA6A,SOX6,AQP4,CADPS,TMEM151A,SON,MYT1L,SOX5,CAMTA1,ADGRL3,TCF12,AZIN2,MAEL,PDE4B,FNDC5,TUB,CADM1,NRXN2,CNTN1,NSD2,PHYHIP,CA10,ZC3H11A,KCNMA1,CALN1,ABI1,TTLL7,EFNA3,RCAN2" MicroRNA hsa-miR-509-5p:mirSVR_highEffct hsa-miR-509-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-15 1.54E-11 9.43E-15 8.65E-14 48 956 "RABEPK,ACLY,CNTNAP3,CSMD2,MDM4,TOMM40L,ASIC4,FHL1,ERICH3,ITSN1,SH3GL2,ZCCHC17,NLGN1,RCOR3,USP33,B3GALT2,CLASP2,ARHGEF7,ZNF638,GPM6B,ZEB1,NRDC,NRGN,GRIA2,TGFBR3,INA,TLL2,PCDH8,LGI1,LINC01102,ANO5,TMEFF2,CCSER2,CNTN1,MEAF6,SF1,FEZ2,OSBPL3,PHACTR3,FMN2,CTNND1,PTPRD,PTPRE,PTPRZ1,SNX27,NKAIN1,HS3ST4,UEVLD" MicroRNA hsa-miR-3186-5p:mirSVR_lowEffct hsa-miR-3186-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-15 1.81E-11 1.11E-14 1.02E-13 31 401 "CHST15,LINC00461,TRIM46,ANK2,CNIH2,MADD,SLC8A3,ASPH,RCOR3,SON,KIF21B,ADGRB2,CNTN2,BRSK2,GRIA4,CYB561A3,TPM4,PDE1A,PFKFB3,NEGR1,ANLN,CELF5,BEST1,SF1,PRKCG,PSMD13,SIRPA,PRDM2,KCNN3,RALGDS,PHC2" MicroRNA hsa-miR-4268:mirSVR_highEffct hsa-miR-4268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.35E-15 1.81E-11 1.11E-14 1.02E-13 36 549 "ADGRV1,CSMD3,RXRG,SORCS1,ADORA3,APBB1,SESN3,SPHKAP,SMARCE1,RCOR3,NPAS3,ZNF302,DCAF5,GJB1,ARHGEF7,OS9,CAMTA1,DDR1,ZEB1,CAMK2G,GRIA4,OLR1,HRH3,HMGB1,PRRX1,SNCAIP,RBPJ,DZIP3,MASP1,BDNF-AS,COPS7A,MED24,PTPRE,PCDH15,RALGDS,BSCL2" MicroRNA hsa-miR-636:PITA hsa-miR-636:PITA_TOP PITA 3.39E-15 1.84E-11 1.12E-14 1.03E-13 22 181 "RTN3,AMER2,SEMA6A,ANK1,SHTN1,SOX5,TBX15,VSTM2A,GRIK2,OPCML,TMEM25,TNS1,PCDH9,DCLK1,LGI1,TPD52,TUB,PKN2,PUM1,RIMS3,ZYG11B,EPB41L1" MicroRNA hsa-miR-4325:mirSVR_highEffct hsa-miR-4325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.58E-15 1.94E-11 1.18E-14 1.09E-13 47 925 "SYNDIG1,CSMD2,MDM4,F3,RTN1,SORCS1,SCN3A,MOBP,SOX6,SELL,PPFIA1,SORBS1,SHTN1,MSRA,ASCL1,SNAP25,C11orf87,NEUROD1,NFIA,GLS,SYT4,VSTM2A,ADAMTS8,RBFOX2,HNRNPK,BTF3L4,MED1,TENM4,PPP3CB,KCNT2,OSBPL3,FMN2,PKN2,NOS1AP,GON4L,DNAJC6,KCNA1,KCNMA1,PEX5,KLRC2,TMEM255A,SLC17A6,DSCAM,JMJD1C,FAM135B,SLC4A10,RCAN2" MicroRNA hsa-miR-378c:mirSVR_highEffct hsa-miR-378c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.70E-15 2.00E-11 1.22E-14 1.12E-13 49 1000 "MAP6,KCNIP2,RXRG,FABP7,SORCS1,SLC44A5,FCGR1A,KIAA1109,FOXG1,CAPRIN2,SORCS3,EIF4G3,BCL2L2,NEUROD1,ACSBG1,ARHGEF7,GLS,SYT4,GNAS,CAMTA1,GRIA4,TMEM25,CDH8,SEZ6L,LGI1,HMGB1,KIAA1549L,CAMKV,C11orf49,BEST1,RNF14,PRKACB,RAB39A,PLPP4,DNAJC6,CADM2,PRTFDC1,PTPRD,KCNJ10,KIF2A,HS3ST4,DSCAM,CAMK1G,RFX4,ZNF248,RBM12,SH3GLB1,UEVLD,BAALC" MicroRNA hsa-miR-23b-3p:TargetScan hsa-miR-23b-3p TargetScan 3.73E-15 2.02E-11 1.23E-14 1.13E-13 47 926 "RIMKLA,ACTN2,EYA1,RXRG,NLGN4X,CHST15,KIAA1109,FGF14,PKP4,NLGN1,MADD,RUFY2,PDE8B,PHYHIPL,PALLD,B3GALT2,CADM3,NEK6,NDUFA5,NFIA,CAMSAP2,ANO4,NRGN,NUDT21,EML4,PSD3,RFFL,REPS2,MAGI1,PDE3B,PDE4B,SCRG1,CADM1,NRXN1,NEGR1,FTO,DOCK7,CTNND2,DNAJC6,CADM2,KCNH1,ARNT2,KCNK1,DLG2,DTNA,JMJD1C,ELAVL4" MicroRNA hsa-miR-23c:TargetScan hsa-miR-23c TargetScan 3.73E-15 2.02E-11 1.23E-14 1.13E-13 47 926 "RIMKLA,ACTN2,EYA1,RXRG,NLGN4X,CHST15,KIAA1109,FGF14,PKP4,NLGN1,MADD,RUFY2,PDE8B,PHYHIPL,PALLD,B3GALT2,CADM3,NEK6,NDUFA5,NFIA,CAMSAP2,ANO4,NRGN,NUDT21,EML4,PSD3,RFFL,REPS2,MAGI1,PDE3B,PDE4B,SCRG1,CADM1,NRXN1,NEGR1,FTO,DOCK7,CTNND2,DNAJC6,CADM2,KCNH1,ARNT2,KCNK1,DLG2,DTNA,JMJD1C,ELAVL4" MicroRNA hsa-miR-23a-3p:TargetScan hsa-miR-23a-3p TargetScan 3.73E-15 2.02E-11 1.23E-14 1.13E-13 47 926 "RIMKLA,ACTN2,EYA1,RXRG,NLGN4X,CHST15,KIAA1109,FGF14,PKP4,NLGN1,MADD,RUFY2,PDE8B,PHYHIPL,PALLD,B3GALT2,CADM3,NEK6,NDUFA5,NFIA,CAMSAP2,ANO4,NRGN,NUDT21,EML4,PSD3,RFFL,REPS2,MAGI1,PDE3B,PDE4B,SCRG1,CADM1,NRXN1,NEGR1,FTO,DOCK7,CTNND2,DNAJC6,CADM2,KCNH1,ARNT2,KCNK1,DLG2,DTNA,JMJD1C,ELAVL4" MicroRNA hsa-miR-7110-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.03E-15 2.18E-11 1.33E-14 1.22E-13 29 349 "ACTN2,GRAMD1B,NLGN4X,ASCL1,SMARCE1,IGSF9B,ATP1A3,GJB1,SEPT3,TMEM151B,DDR2,GRID1,TGFBR3,FBXL16,ZDHHC22,TNS1,CDH8,PTGDR2,GPR37L1,TMPRSS5,GDAP1L1,RIMS4,DPYSL5,CADM2,SMG7,TMCC2,NAV2,ZYG11B,ELAVL3" MicroRNA hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.12E-15 2.23E-11 1.36E-14 1.25E-13 28 323 "SERPINA3,ACTN2,GRAMD1B,NLGN4X,ASCL1,IGSF9B,ATP1A3,GJB1,SEPT3,GPR26,TMEM151B,DDR2,GRID1,TGFBR3,FBXL16,ZDHHC22,TNS1,CDH8,PTGDR2,GPR37L1,GDAP1L1,CRLS1,KIAA0408,CADM2,SMG7,NAV2,ZYG11B,ELAVL3" MicroRNA hsa-miR-766:mirSVR_highEffct hsa-miR-766:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.25E-15 2.30E-11 1.40E-14 1.28E-13 42 751 "ZFYVE27,ASIC1,LINC00461,APBB1,NSG2,DNAH17,DDX25,NRG3,INKA2,RND1,SEPT3,GNAS,PSRC1,GRIA2,AIFM1,TPM3,TMPRSS5,CHGA,DUSP26,NLGN3,PLXNB3,BEST1,BTF3L4,POU3F2,CSF3R,PRKCG,WBP1L,PSMD13,PTHLH,CADM2,HP1BP3,CDH20,KCNK2,SLC25A48,DTNA,RET,ARHGEF10L,PHC2,SEC61A2,EFNA3,C2orf80,SEZ6" MicroRNA hsa-miR-875-5p:mirSVR_highEffct hsa-miR-875-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.25E-15 2.30E-11 1.40E-14 1.28E-13 40 683 "SYT9,LGR4,EYA1,MDM4,CDC7,SORCS1,CHST15,MOBP,PPM1E,SYBU,LRRC55,SCG3,SMARCE1,RCOR3,MEGF11,NAP1L2,GLS,DDHD2,TCF7L2,GPR88,TLL2,HPS5,PDE1A,PDYN,ANO5,NEGR1,PMP2,BTF3L4,ACBD5,TENM4,PRKACB,NRSN1,MASP1,ITGAV,LRP8,COPS7A,OCIAD1,DTNA,RAVER2,RPE65" MicroRNA hsa-miR-7-5p:TargetScan hsa-miR-7-5p TargetScan 4.39E-15 2.38E-11 1.44E-14 1.32E-13 31 405 "RIMKLA,ECSIT,CSMD3,HPCAL4,CCDC80,DGKD,ATP2B2,GABBR1,CADM3,CLASP2,FAM168A,NFIA,GOLGB1,DIRAS1,HAP1,PAX6,PDE4B,LRTM2,CADM1,PIK3CD,CCSER2,CRLS1,MAPK10,FAM131B,CDH20,KCNA6,RAB5B,CALN1,CACNG7,GPR61,ABI2" MicroRNA hsa-miR-524-3p:mirSVR_lowEffct hsa-miR-524-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-15 2.38E-11 1.44E-14 1.32E-13 31 405 "SYT9,ADD3,TOMM40L,LRRC7,PDZD4,SEMA6C,ANK3,SORCS3,B3GAT1,ILDR2,ZSWIM8,AHCYL1,SPART,AJAP1,CACNB2,EML4,VXN,GRID1,CCKBR,LINC00839,CHGA,CHRM1,ANLN,PLXNB3,PPP2R5C,TOX,MAGI2,C1orf109,SRGAP3,KCNJ10,SLC25A48" MicroRNA hsa-miR-769-5p:mirSVR_highEffct hsa-miR-769-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.67E-15 2.53E-11 1.53E-14 1.41E-13 36 555 "CNTNAP3,ARID1A,SLITRK1,MOBP,MOG,ITSN1,ZNF365,SLC1A7,TAGLN3,ADHFE1,PCDH11X,GOLGB1,WSCD1,VSTM2A,NUMA1,GRIA2,PCDH9,LGI1,TPD52,FNDC5,BEST3,HERC2P3,DUSP26,GDAP1L1,CRLS1,RGS6,SYTL2,HP1BP3,BLOC1S6,KCNK2,PCDH15,HS3ST4,ABCC9,FAM135B,SIDT2,EN2" MicroRNA hsa-miR-556-5p:mirSVR_highEffct hsa-miR-556-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.82E-15 2.61E-11 1.58E-14 1.45E-13 49 1007 "ABAT,SYT9,LDLRAD3,SORCS1,SLC44A5,MOBP,SGIP1,PKP4,APC,MAGI3,SLC14A1,SMARCE1,KIF1B,STOX1,NEUROD1,AJAP1,GLS,CNTN2,INA,TJP1,LGI1,PDE1A,BEST3,JAM2,HEPACAM,NEGR1,A2ML1,TJP2,DNAJC12,CNTN1,PMP2,MEAF6,PRRX1,ACBD5,MFSD4A,PPP3CB,MICAL2,USP54,IGSF1,PUM1,PTHLH,MAGI2,OLFM3,KCNK1,OLIG1,RET,USH1C,FAM135B,RNF220" MicroRNA hsa-miR-450b-3p:mirSVR_highEffct hsa-miR-450b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.93E-15 2.67E-11 1.62E-14 1.48E-13 36 556 "FABP7,SLC30A10,PKP4,NTNG1,SMARCE1,RCOR3,AHCYL1,B4GALNT1,RAP1GAP2,SPART,INKA2,GLS,GPM6B,GRIA1,GRIA4,RFFL,AIFM1,TNFRSF1B,LGI1,TPM3,CP,CHD1L,SNCAIP,MAPK10,BRINP3,CA10,JAKMIP2,ELMO1,HP1BP3,COPS7A,PTPRE,PCDH15,KCNMA1,RFX4,FAM135B,SEC61A2" MicroRNA hsa-miR-4287:mirSVR_highEffct hsa-miR-4287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-15 2.78E-11 1.68E-14 1.54E-13 43 790 "ASIC1,MEG3,KLHL32,GALNT13,WAC,SLC30A10,HPCAL4,ASRGL1,CDC42BPA,MAGI3,GPAM,SORBS1,BCAS1,BCO1,SORCS3,SMARCE1,GABBR1,SON,MYT1L,ILDR2,ZSWIM8,AHCYL1,ARPP21,FGF17,RGL1,ADHFE1,CASTOR3,TBX15,CRB1,TIE1,CDH8,LGI1,HMGB1,SLC25A27,POU3F2,MAPK10,PTHLH,STMN4,SMG7,PAK5,PHC2,SLC4A10,SEZ6" MicroRNA hsa-miR-2276:mirSVR_highEffct hsa-miR-2276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.84E-15 3.16E-11 1.92E-14 1.76E-13 43 793 "SDE2,EYA1,ARID1A,SLC30A10,SELL,AMPH,ITSN1,MAGI3,PAAF1,ZNF365,LRRC55,SORCS3,SOX1,MYT1L,AHCYL1,JPH4,GFAP,KIRREL3,ADHFE1,RND1,ASTN2,GOLGB1,WSCD1,ZEB1,GRIA2,TJP1,MAGI1,PIRT,DUSP26,CADM1,ZFYVE9,ACBD5,CNRIP1,PHACTR3,RBPJ,PLPPR4,NTM,CAB39L,SLC17A6,C12orf4,SSPN,ABI2,RPE65" MicroRNA hsa-miR-1179:PITA hsa-miR-1179:PITA_TOP PITA 6.02E-15 3.26E-11 1.97E-14 1.81E-13 25 253 "SYNDIG1,ADD3,CDC7,TOMM40L,ANK1,ITSN1,MAGI3,ARHGAP5,ASCL1,SNAP25,MYT1L,CAB39,CLASP2,CAMTA1,GPM6A,GRIA2,PDYN,HMGB1,MED1,DZIP3,PTCH1,PMEPA1,CADM2,KCNA1,PTPRO" MicroRNA hsa-miR-129-3p:mirSVR_highEffct hsa-miR-129-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.57E-15 3.56E-11 2.15E-14 1.97E-13 35 530 "ACLY,RTN3,MEG3,IL17D,RTKN,NDRG2,LINC00461,LRRC7,CACHD1,SLC8A3,SON,JPH4,CLASP2,COLGALT2,ERBIN,SYT4,CAMSAP2,TMEM136,PTBP2,CECR2,GRIK4,CRB1,TMEM257,TNR,TPD52,PDYN,DOCK7,PKN2,CTNND1,TOMM20,PRDM2,FAM135B,TMEM100,RCAN2,BAALC" MicroRNA hsa-miR-542-3p:mirSVR_highEffct hsa-miR-542-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.70E-15 3.63E-11 2.19E-14 2.01E-13 46 904 "TTYH1,RTN3,MRVI1,MDM4,KLHL32,FCGR1A,ASRGL1,PPFIA1,ZCCHC17,SYBU,ASPH,DDX25,SORCS3,NRG3,PHYHIPL,AHCYL1,NCAM1,COLGALT2,NDUFA5,DDR1,TCF12,CECR2,GPR88,HPS5,TPM3,HPSE2,PFKFB3,ANLN,TJP2,BEST1,PRRX1,DOCK7,TOMM20,TUBB2B,ITIH2,COPS7A,MAGI2,KCNA1,SMG7,PLPPR4,KCNMA1,DTNA,ABCC9,RFX4,JMJD1C,VWA5A" MicroRNA hsa-miR-517b:mirSVR_lowEffct hsa-miR-517b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.70E-15 3.63E-11 2.19E-14 2.01E-13 38 626 "KLRC4,HOGA1,PPFIA1,APBB1,TACC2,SHTN1,TAGLN3,CAPRIN2,SORCS3,RCOR3,WDTC1,AJAP1,NFIA,CACNB2,GPR19,GRIA2,GRIN1,GPR88,OMG,CRB1,TJP1,CDC42,PRMT8,SEMA5B,FLRT1,POU3F2,PPP3CB,ATRNL1,VCAN,PKN2,CSDE1,AK5,SLC17A6,RFX4,ATL1,TTLL7,CBLN2,UEVLD" MicroRNA hsa-miR-1193:mirSVR_highEffct hsa-miR-1193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.83E-15 3.70E-11 2.23E-14 2.05E-13 36 562 "RABEPK,ACER3,SYT9,CSMD3,LRRC7,ASIC4,SH3GL2,RUFY2,SMARCE1,KIF21B,NMNAT2,NELL1,VAMP1,ZNF638,CAMTA1,GPM6A,CACNB2,GRIK3,GRIN1,DAAM2,CDC42,PTGDR2,TPD52,ZNF384,PDE3B,PLEKHB1,SPATA6,RBPJ,PLPPR5,ITGAV,CADM2,ZC3H11A,PTPRD,PTPRO,PAK5,VWA5A" MicroRNA hsa-miR-1972:mirSVR_highEffct hsa-miR-1972:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.97E-15 3.77E-11 2.28E-14 2.09E-13 42 762 "RTN3,MOBP,ERICH3,NTNG1,NAXD,RCOR3,ZSWIM8,JPH4,KIF1B,GART,NPAS3,RGL1,SEPT3,ABCC8,GOLGB1,CACNB2,NRDC,VSTM2A,GRIA4,USP2,AIFM1,PDE1C,HPSE2,HERC2P3,CCDC136,BTBD17,POU3F2,PPP3CB,ATRNL1,PRKACB,PKN2,EDRF1,NOS1AP,MASP1,CEP170,PLPPR4,PTPRO,KCND3,KCNK2,DPP6,EPB41L1,BAALC" MicroRNA hsa-miR-4290:mirSVR_highEffct hsa-miR-4290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.05E-15 3.82E-11 2.30E-14 2.11E-13 30 384 "SERPINA3,SYT9,ADGRV1,MDM4,BCAS1,ATP1A2,USP33,ZCCHC24,NELL1,SEPT3,OS9,CAMTA1,UNC5D,ZEB1,CAMK2G,IGFN1,PRMT8,HEPACAM,ZFYVE9,CAMKV,A2ML1,OPALIN,PLXNB3,PPP3CB,PHACTR3,CAB39L,NKAIN1,C12orf4,SLC6A15,PIANP" MicroRNA hsa-miR-384:mirSVR_highEffct hsa-miR-384:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.29E-15 3.95E-11 2.38E-14 2.18E-13 47 943 "PRR5L,ACTN2,MDM4,CLIP1,FABP7,AMER2,SLC44A5,TOMM40L,LRRC7,SOX6,NTNG1,API5,SLC8A3,CCDC88A,SHANK2,ASPH,SCN3B,NCAM1,ZNF302,ERBIN,PCDH11X,SYT4,DDHD2,UNC5D,GPM6B,CACNB2,GRIA2,GRIA4,GRID1,MAGI1,SERPINE2,CADM1,CNTN1,P2RY12,CRLS1,PRKACB,FMN2,USP54,SYTL2,PSMD13,PTHLH,PRTFDC1,KCNMA1,NAV2,FAM135B,SEC61A2,RCAN2" MicroRNA hsa-miR-4302:mirSVR_highEffct hsa-miR-4302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.29E-15 3.95E-11 2.38E-14 2.18E-13 42 763 "RPL38,MEG3,GPR158,ITSN1,SH3GL2,SORBS1,CADPS,SMARCE1,TTLL9,SEPT3,TBX15,CACNB2,PTBP2,CECR2,VSTM2A,GRIA4,KCNK10,PDE3B,BEST3,ZFYVE9,BEST1,MED1,PNKD,PPP2R5C,NCAN,PKN2,MASP1,BLOC1S6,SMG7,NTM,KCNJ10,PCDH15,RASGRF1,FAM13C,RFX4,RFX5,JMJD1C,TTLL7,RERGL,ABI2,PRRT4,UEVLD" MicroRNA hsa-miR-205:PITA hsa-miR-205:PITA_TOP PITA 7.69E-15 4.16E-11 2.51E-14 2.30E-13 26 280 "SYT9,RTN3,CLIP1,PI16,MAGI3,SORBS1,PHYHIPL,JPH4,CAMSAP2,WWC1,GPM6A,GRIA4,RBFOX2,PDE3B,CADM1,MED1,MAGI2,OCIAD1,SMG7,SNX27,DLG2,PHC2,RBM12,ABI2,EPB41,EPB41L1" MicroRNA hsa-miR-133a-3p.1:TargetScan hsa-miR-133a-3p.1 TargetScan 7.98E-15 4.32E-11 2.60E-14 2.39E-13 31 414 "FGF1,LRRC7,HPCAL4,BCL2L2,GANAB,MYRF,GPM6A,DDR1,PTBP2,PCDHGA3,CAMK2G,NUMA1,GRIK3,DAAM2,CDC42,BEST3,PFKFB3,DLGAP3,CELF5,PRRX1,PACSIN1,RBPJ,CTNND1,NOS1AP,PTPRD,KCND3,PTPRZ1,DNM2,ABCC9,ARHGAP12,CBLN2" MicroRNA hsa-miR-204-5p:TargetScan hsa-miR-204-5p TargetScan 8.03E-15 4.35E-11 2.61E-14 2.39E-13 36 565 "DPF1,EPS8,RIMKLA,LGR4,ADARB2,ADD3,GRAMD1B,PPM1E,LRRC55,ARHGAP5,NRG3,MYT1L,NEK6,NPAS3,RAP1GAP2,BCL2L2,NFIA,GPM6A,OPCML,P2RX7,HMGB1,FTO,PRRX1,FAT3,POU3F2,CHD5,NOS1AP,LRP8,KCNA1,PTPRD,KCND3,RABGAP1L,DNM2,SEC61A2,ELAVL3,ELAVL4" MicroRNA hsa-miR-211-5p:TargetScan hsa-miR-211-5p TargetScan 8.03E-15 4.35E-11 2.61E-14 2.39E-13 36 565 "DPF1,EPS8,RIMKLA,LGR4,ADARB2,ADD3,GRAMD1B,PPM1E,LRRC55,ARHGAP5,NRG3,MYT1L,NEK6,NPAS3,RAP1GAP2,BCL2L2,NFIA,GPM6A,OPCML,P2RX7,HMGB1,FTO,PRRX1,FAT3,POU3F2,CHD5,NOS1AP,LRP8,KCNA1,PTPRD,KCND3,RABGAP1L,DNM2,SEC61A2,ELAVL3,ELAVL4" MicroRNA hsa-miR-768-3p:PITA hsa-miR-768-3p:PITA_TOP PITA 8.39E-15 4.54E-11 2.73E-14 2.50E-13 29 359 "ERMN,NLGN4X,PPM1E,NTNG1,NLGN1,SNAP25,SOX1,SOX5,CLASP2,GLS,ADGRL3,GPM6A,PTBP2,PSD3,GRIA4,ZFP91,PCDH8,PCDH9,PDE4B,NEGR1,POU3F2,PPP3CB,RIMS4,TOX,LRRTM3,CA10,OLFM3,SLC17A6,RTN4" MicroRNA hsa-miR-630:mirSVR_highEffct hsa-miR-630:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.47E-15 4.59E-11 2.75E-14 2.52E-13 54 1217 "CDHR1,F3,CDC7,GRAMD1B,TMEM156,FGF14,FOXG1,ANK3,ITSN1,APBA2,NTNG1,SLITRK3,MIER1,MSR1,CADPS,SPHKAP,SLIT1,KIF21B,SALL3,GART,NAP1L2,LMO3,NDUFA5,GLS,GNAS,CAMTA1,UNC5D,ADGRL3,EML4,GRIA2,TGFBR3,INA,PCDH9,RBFOX2,LGI1,TPM4,TJP2,ACBD5,RGS6,KCNT2,DZIP3,PRKCZ,USP54,KLK6,DNAJC6,PTPRZ1,NTM,PCDH15,KIF2A,PID1,RASGRF1,FAM13C,PAK5,RFX4" MicroRNA hsa-miR-338-3p:TargetScan hsa-miR-338-3p TargetScan 8.89E-15 4.82E-11 2.89E-14 2.65E-13 28 333 "MAPT,ADORA1,LRRC7,MOG,RPH3A,MYT1L,CPLX2,BCL2L2,NEUROD1,FAM168A,NFIA,PCDH11X,CAMK2A,CAMK2G,GRIN1,PIRT,HPSE2,CADM1,KIAA1549L,OSBPL3,KCNA4,DLG2,KIF2A,C12orf4,JMJD1C,ARHGEF10L,SEC61A2,ABI2" MicroRNA hsa-miR-3162:mirSVR_highEffct hsa-miR-3162:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.05E-15 4.90E-11 2.94E-14 2.70E-13 38 632 "CDHR1,EYA1,ATAT1,RTKN,NDRG2,SORCS1,PLA2G6,MOBP,SOX6,ZNF365,SPHKAP,SORCS3,RCOR3,B3GAT1,WDTC1,ARPP21,TTLL9,NEUROD1,SLCO1C1,CASTOR3,PCDH11X,POPDC3,GOLGB1,TMEM9,NEURL1,UBTF,KCNT2,ZNF385B,CADM2,HP1BP3,COPS7A,SV2A,PCDH15,PYGM,KLRC3,FAM13C,DTNA,RLBP1" MicroRNA hsa-miR-4314:mirSVR_highEffct hsa-miR-4314:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-15 4.92E-11 2.95E-14 2.70E-13 49 1024 "ASIC1,SORCS1,TOMM40L,LRRTM4,FGF1,LRRC7,ITSN1,NLGN1,PAAF1,CCDC88A,SPHKAP,CAPRIN2,ASPH,RCOR3,ZSWIM8,ARPP21,KIF1B,BCL2L2,GLS,CACNB2,PTPN5,DAAM2,CA14,CASC2,TLX1,JAM2,HEPACAM,BEST1,MED1,PPP3CB,ATRNL1,USP54,FGFR1OP2,TOMM20,LRRTM3,PRTFDC1,PCDH15,KCNMA1,RAB5B,PARP11,GOPC,FAM13C,DTNA,RFX4,ARHGEF10L,VANGL2,SEC61A2,RNF220,RAVER2" MicroRNA hsa-miR-1911:mirSVR_lowEffct hsa-miR-1911:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.09E-15 4.92E-11 2.95E-14 2.70E-13 42 768 "TTYH1,ZFYVE27,SRARP,F3,ADORA3,FCGR1A,BBOX1,SOX6,SGIP1,ARHGAP5,SMARCE1,EIF4G3,SOX5,TTLL9,KIF1B,GART,NDUFA5,DCAF5,KIRREL3,PCDH11X,GNG4,GPR17,PTBP2,VSTM2A,CRB1,TMEM257,PCDH8,PCDH9,BEST3,PPP2R5C,PPP3CB,KCNT2,DOCK7,USP54,GON4L,PRDM2,HP1BP3,CEP170,SEC61A2,RNF220,ARHGAP12,SEZ6" MicroRNA hsa-miR-223-3p:TargetScan hsa-miR-223-3p TargetScan 9.11E-15 4.93E-11 2.95E-14 2.71E-13 26 282 "ARID1A,F3,SCN3A,PKP4,APC,CLSTN1,CSPG5,NFASC,FAM168A,NFIA,CNDP1,GPM6B,PTBP2,PSD3,OPCML,AIFM1,PAX6,PDE3B,PFKFB3,RBPJ,PRKACB,KIAA1755,BRINP3,RIMS3,DNAJC6,ABI2" MicroRNA hsa-miR-671-5p:mirSVR_highEffct hsa-miR-671-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.36E-15 5.07E-11 3.03E-14 2.78E-13 37 600 "SYT9,MOBP,APC,GPAM,SORBS1,PAAF1,DKK3,SEPT3,CASTOR3,WSCD1,GPM6A,GPM6B,VXN,GRIN1,CYB561A3,OMG,CCKBR,MFSD2A,AIFM1,HPS5,HPCA,HEPACAM,SERPINE2,ST8SIA5,SF1,PPP2R5C,ATRNL1,IGSF1,PLPPR5,HP1BP3,PTPRD,SV2A,KCNJ10,KCNK1,RAD52,PHC2,SEC61A2" MicroRNA hsa-miR-582-3p:PITA hsa-miR-582-3p:PITA_TOP PITA 9.46E-15 5.12E-11 3.06E-14 2.81E-13 25 258 "MAPT,ADCY2,NLGN1,ARHGAP5,DACH2,ASCL1,ZCCHC24,NPAS3,NCAM1,CLASP2,DCAF5,RGL1,BTRC,FBXL16,CDH10,TPM4,PCSK2,ZNF384,PDYN,CAMKV,KCNT2,CTNND2,CA10,CSDE1,ELAVL3" MicroRNA hsa-miR-200c*:mirSVR_highEffct hsa-miR-200c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.70E-15 5.25E-11 3.14E-14 2.88E-13 35 537 "TMEM74,EYA1,ARID1A,KLRC4,GALNT13,SFPQ,CDC42BPA,SH3GL2,NTNG1,DGKZ,ZNF365,ATP1A2,MYT1L,SYT4,CAMSAP2,LILRA1,PRLHR,CRB1,INA,C1orf94,PCDH8,LGI1,ZBED5,TMEFF2,OPALIN,MEAF6,VCAN,PRDM2,KIF2A,ABI1,DTNA,CRTAC1,TTLL7,SLC4A10,EPB41" MicroRNA hsa-let-7e:mirSVR_highEffct hsa-let-7e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.80E-15 5.31E-11 3.17E-14 2.91E-13 43 805 "LGR4,MEG3,ARID1A,MDM4,CLIP1,KLHL32,ERMN,FGR,MOBP,PAAF1,GABBR1,KIF1B,FXYD6,CLASP2,ADHFE1,GANAB,ACSL6,CACNB2,TCF12,ADAMTS8,CRB1,TGFBR3,AIFM1,SERPINE2,SLC25A27,PRRX1,MFSD4A,OSBPL3,IGSF1,MASP1,SYNC,PRDM2,KCNJ11,KCNK1,DLG2,TMEM255A,DPP6,C12orf4,SLC25A18,RFX5,ZNF248,SYT15,PLEKHO1" MicroRNA hsa-miR-200b*:mirSVR_highEffct hsa-miR-200b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-14 5.59E-11 3.33E-14 3.06E-13 47 952 "SDE2,TMEM74,WLS,NLGN4X,LRRC7,MOBP,RUFY2,MSR1,NSG2,SPHKAP,ASTN1,SMARCE1,ENKUR,ARPP21,KIF1B,C11orf87,GLS,DDHD2,PRUNE2,GRIA4,C1orf94,LGI1,TPM4,HMGB1,ZBED5,NLGN3,ST8SIA5,BTF3L4,NSD2,NXPH1,CRLS1,KCNT2,ATRNL1,RBPJ,PRKAB2,NRSN1,EDRF1,LRRTM3,ITGAV,KCNA4,PLPPR4,KLRC2,DPP6,ABI1,ABCC9,VWA5A,TMEM100" MicroRNA hsa-miR-767-5p:mirSVR_highEffct hsa-miR-767-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-14 5.83E-11 3.47E-14 3.19E-13 41 737 "SLITRK1,GALNT13,WAC,SCN3A,LRRC7,FOXG1,AMPH,USP28,CACHD1,ST3GAL3,CAPRIN2,ASPH,CAB39,ARPP21,NPAS3,NASP,ARHGEF7,KAZN,GNAS,DDHD2,CAMTA1,NODAL,CAMSAP2,TCF7L2,PTBP2,CYB561A3,TF,CRB1,TJP1,PCDH9,FNDC5,GDAP1L1,A2ML1,PRKAB2,CTNND2,BDNF-AS,CSDE1,PTPRZ1,KCNJ11,NAV2,ARHGEF10L" MicroRNA hsa-miR-4259:mirSVR_highEffct hsa-miR-4259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-14 5.91E-11 3.52E-14 3.23E-13 37 603 "DSCAML1,CHST15,SNX32,ANK3,ITSN1,APC,ZCCHC17,MIER1,SLN,NPAS3,ADHFE1,SLCO1C1,PRLHR,ZEB1,GRIA1,GRIA4,GRID1,RFFL,GRIK2,SPX,USP2,P2RX7,MAEL,PCSK2,CHD1L,SF1,FMN2,USP54,CTNND1,HP1BP3,SV2A,PCDH15,TMEM255A,ATN1,ZYG11B,INSYN2,EPB41" MicroRNA hsa-miR-591:mirSVR_highEffct hsa-miR-591:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-14 6.32E-11 3.76E-14 3.45E-13 32 449 "ADAR,SLITRK1,TESK2,SCN3A,PPM1E,ZNF365,SPHKAP,ASPH,MEGF11,GANAB,PCDH11X,ASTN2,GNAS,ZEB1,GRM3,MFSD2A,INA,MS4A7,SLC36A4,PPP3CB,ATRNL1,DZIP3,MAPK10,EDRF1,KCNK2,KCNN3,PEX5,DNAH9,SUSD4,ZYG11B,RET,ARHGAP12" MicroRNA hsa-miR-1285:PITA hsa-miR-1285:PITA_TOP PITA 1.19E-14 6.45E-11 3.84E-14 3.52E-13 23 214 "SDE2,CSMD2,NLGN4X,ITSN1,MYBPC1,JPH4,LHFPL4,CPLX2,PCDH11X,BTRC,WWC1,TCF12,RBFOX2,GDAP1L1,FAT3,NXPH1,PPP3CB,RIMS4,LRRTM3,ZC3H11A,KCNK2,DLG2,WIPF2" MicroRNA hsa-miR-612:PITA hsa-miR-612:PITA_TOP PITA 1.19E-14 6.45E-11 3.84E-14 3.52E-13 23 214 "SDE2,CSMD2,NLGN4X,ITSN1,MYBPC1,JPH4,LHFPL4,CPLX2,PCDH11X,BTRC,WWC1,TCF12,PSD3,RBFOX2,GDAP1L1,NXPH1,PPP3CB,RIMS4,LRRTM3,ZC3H11A,KCNK2,DLG2,WIPF2" MicroRNA hsa-miR-449c*:mirSVR_lowEffct hsa-miR-449c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-14 6.57E-11 3.90E-14 3.58E-13 46 919 "CDHR1,MRVI1,CLIP1,SORCS1,FOXRED2,DRAXIN,LRRC7,FOXM1,ANK3,ZNF365,NSG2,SLC14A1,DACH2,PDE8B,CAPRIN2,BRINP2,ATP1A2,USP33,CADM3,ARPP21,NCAM1,INKA2,UNC5D,ACSL6,TCF12,SHISA7,CRB1,ARHGAP19,CHD1L,PPP3CB,OSBPL3,DOCK7,KIAA0408,DPYSL5,CADM2,CCDC3,FAM66C,RAP1GAP,SLC6A15,JMJD1C,FAM135B,ZNF248,ABI2,RAVER2,TMEM100,BAALC" MicroRNA hsa-miR-129-3p:PITA hsa-miR-129-3p:PITA_TOP PITA 1.33E-14 7.20E-11 4.27E-14 3.92E-13 24 238 "AQP4,SCN3B,AHCYL1,NMNAT2,JPH4,ERBIN,SYT4,CAMSAP2,CACNA1E,FNDC5,CADM1,SEMA5B,MED1,RIMS3,TOMM20,DLG2,RAB5B,CALN1,FAM135B,VANGL2,ELAVL3,TMEM100,RCAN2,BAALC" MicroRNA hsa-miR-129*:mirSVR_highEffct hsa-miR-129*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-14 7.30E-11 4.33E-14 3.97E-13 35 543 "ACLY,RTN3,MEG3,IL17D,RTKN,NDRG2,LINC00461,LRRC7,CACHD1,SLC8A3,SON,JPH4,COLGALT2,ERBIN,SYT4,CAMSAP2,TMEM136,PTBP2,CECR2,GRIK4,CRB1,TMEM257,TNR,TPD52,PDYN,DOCK7,PKN2,CTNND1,TOMM20,PRDM2,FAM135B,SSPN,TMEM100,RCAN2,BAALC" MicroRNA hsa-miR-802:PITA hsa-miR-802:PITA_TOP PITA 1.40E-14 7.60E-11 4.51E-14 4.14E-13 32 452 "RTN1,APC,NLGN1,SOX5,CAB39,CLASP2,NEUROD1,GLS,UNC5D,ADGRL3,CAMK2A,RFFL,PCDH9,RBFOX2,LGI1,KIAA1549L,NMT2,CCSER2,BTF3L4,SF1,CRMP1,EDRF1,LRRTM3,PTCH1,KCNA4,PTPRD,PTPRZ1,TMEM255A,GOPC,GNE,JMJD1C,ELAVL3" MicroRNA hsa-miR-431:mirSVR_highEffct hsa-miR-431:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.41E-14 7.62E-11 4.52E-14 4.15E-13 37 608 "SDE2,SORCS1,CHST15,HPCAL4,TRIM46,FOLH1,API5,PAAF1,MIER1,SON,LMO3,DCLK2,CAMTA1,CAMSAP2,PSRC1,GPM6A,LILRA1,ZEB1,DAAM2,C1orf94,LGI1,PDE2A,PDE3B,PDE4B,CHRM1,BTF3L4,PNKD,RGS6,VCAN,PRDM2,KCNC1,PTPRZ1,SRGAP3,KCNMA1,RTN4,PIANP,YY1AP1" MicroRNA hsa-miR-517*:mirSVR_highEffct hsa-miR-517*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-14 7.95E-11 4.71E-14 4.32E-13 42 779 "ATAT1,MDM4,NDRG2,KLHL32,RTN1,CDC7,FCGR1A,SLC30A10,MOBP,ITSN1,STK32C,LRRC55,RCOR3,SNAP25,JPH4,NPAS3,DIRAS1,GRID1,CYB561A3,P2RX7,TMEM9,TLL2,LGI1,TPM4,PDE3B,PIRT,ZMYND8,NEGR1,A2ML1,ST8SIA5,FEZ2,VCAN,PRKACB,DOCK7,MASP1,BRINP3,C1orf109,PCDH15,PID1,PARP11,FAM13C,SSPN" MicroRNA hsa-miR-380*:mirSVR_highEffct hsa-miR-380*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-14 8.01E-11 4.75E-14 4.35E-13 29 367 "ACHE,LGR4,RTN1,TESK2,LRRC55,ASCL1,CAPRIN2,ASPH,SORCS3,ASTN1,EIF4G3,KIF21B,NPAS3,STOX1,GPM6B,VWC2,GRIK2,TLX1,CADM1,MICAL2,OSBPL3,PRKACB,PLPPR5,ITGAV,DBX2,FAM135B,SSPN,ELAVL4,EPB41L1" MicroRNA hsa-miR-598:mirSVR_lowEffct hsa-miR-598:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-14 8.08E-11 4.78E-14 4.39E-13 32 453 "RABEPK,ACER3,SEMA6A,MOBP,MIER1,ASPH,B3GALT2,TTLL9,RAP1GAP2,GNAS,KLHL4,ANO4,AZIN2,CAMK2A,GRIA4,TMEM9,GUCY1A1,ZFP91,CHD1L,PPP3CB,CHD5,CTNND2,WBP1L,PLPPR1,COPS7A,CEP170,KCNA1,NTM,DLG2,DTNA,JMJD1C,FAM135B" MicroRNA hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA_TOP PITA 1.50E-14 8.12E-11 4.80E-14 4.40E-13 28 340 "MDM4,SCN3A,APBA2,CACHD1,ARHGAP5,CCDC88A,RCOR3,MYT1L,B3GALT2,NFASC,RGL1,CAMTA1,CAMSAP2,GPM6B,TJP1,MAGI1,NXPH1,POU3F2,PPP3CB,HES5,RIMS3,SYNC,LRRTM3,DNAJC6,LRP8,WIPF2,RBM12,ELAVL4" MicroRNA hsa-miR-499a-5p:TargetScan hsa-miR-499a-5p TargetScan 1.55E-14 8.38E-11 4.95E-14 4.55E-13 27 314 "ABAT,FOXG1,APC,KIAA1614,FYN,AHCYL1,FAM168A,CACNB2,PTBP2,EML4,PSD3,PDE3B,SCRG1,ACBD5,PPP3CB,PRKAB2,FAM131B,ANKS1B,HP1BP3,LRP8,NAV2,KCNN3,ABI1,RNF220,RBM12,ELAVL4,EPB41L2" MicroRNA hsa-miR-3197:mirSVR_lowEffct hsa-miR-3197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.56E-14 8.43E-11 4.98E-14 4.57E-13 38 643 "EMID1,MBP,ECSIT,LDLRAD3,ADARB2,CNIH2,ITSN1,NTNG1,LRRC55,CAPRIN2,BRINP2,USP33,B4GALNT1,ADAM15,GFAP,KIRREL3,SEPT3,PSRC1,HAP1,TMEM151B,NUMA1,LINC00839,FBXL16,TMEM9,DAAM2,LGI1,UBTF,CELF5,NKAIN4,PLCH2,TOX,WBP1L,PEX5,DLG2,PARP11,L1CAM,ARHGEF10L,SEC61A2" MicroRNA hsa-miR-3183:mirSVR_highEffct hsa-miR-3183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-14 8.46E-11 4.99E-14 4.58E-13 43 816 "CSMD3,LRRTM4,PAAF1,SFMBT2,RUFY2,CSPG5,TAGLN3,MTR,RCOR3,NRG3,ZCCHC24,B4GALNT1,FGF17,AJAP1,ARHGEF7,CAMTA1,UNC5D,PTBP2,GRIA2,ADAMTS8,TGFBR3,FBXL16,CHGA,GDAP1L1,NRXN1,CRLS1,MICAL2,KIAA1755,PLD5,IGSF1,ANKS1B,PLPPR5,CA10,BDNF-AS,PRDM2,RABGAP1L,SLC25A48,GNE,ABCC9,SLC6A15,RGS7,RLBP1,SLC4A10" MicroRNA hsa-miR-657:mirSVR_highEffct hsa-miR-657:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-14 9.38E-11 5.53E-14 5.08E-13 40 713 "SDE2,ABAT,RTN3,ATAT1,SLC44A5,FHL1,ITSN1,LRRC55,SLC8A2,CCDC88A,SLIT1,SLN,ATM,EIF4G3,DKK3,MYT1L,B3GALT2,PCDH11X,DCLK2,DDHD2,GNG4,TCF7L2,GRIA4,TPD52,ZMYND8,ST8SIA5,SULT4A1,CNTN1,PMS2,MED1,DZIP3,FGFR1OP2,TOX,KCNC1,DLG2,KLRC2,PID1,SLC6A15,CBLN2,YY1AP1" MicroRNA hsa-miR-566:mirSVR_lowEffct hsa-miR-566:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-14 9.79E-11 5.77E-14 5.29E-13 27 316 "MAG,ABAT,PLEKHG5,LCNL1,DISP3,FGF1,FHL1,ANK3,SMARCE1,CADM3,ILDR2,SEPT3,CNTN2,RFFL,GRIN1,LEFTY2,TPM4,CHGA,ARHGAP22,DLGAP3,CABP1,CELF5,NECAB2,KCNJ11,DNAH9,ARHGEF10L,EEF1A2" MicroRNA hsa-miR-592:PITA hsa-miR-592:PITA_TOP PITA 1.81E-14 9.82E-11 5.79E-14 5.31E-13 22 196 "WLS,GPR158,ANK3,LRRC4C,RCOR3,SNAP25,ZCCHC24,CPLX2,NCAM1,LMO3,NFIA,UNC5D,ADGRL3,ACSL6,CACNB2,TJP1,PCDH9,NEGR1,KCNT2,MAGI2,PTPRD,SUSD4" MicroRNA hsa-miR-423-3p:mirSVR_lowEffct hsa-miR-423-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.82E-14 9.84E-11 5.79E-14 5.31E-13 30 398 "LOC100128239,IL17D,ATAT1,TMEM156,PLA2G6,PKNOX2,SLC14A1,ARFGAP1,ATP1A2,CADM3,GFAP,ZNF638,KAZN,PRLHR,CCKBR,SPX,CDH8,CHGA,HERC2P3,FTO,FEZ2,PSMD13,SIRPA,PRDM2,KCNJ10,NKAIN1,DNAH9,ARHGEF10L,SEC61A2,RNF220" MicroRNA hsa-miR-153:PITA hsa-miR-153:PITA_TOP PITA 1.87E-14 1.01E-10 5.95E-14 5.46E-13 28 343 "TESK2,SFPQ,ANK1,USP28,APC,AQP4,SLC1A2,TAGLN3,SNAP25,PALLD,NEUROD1,GLS,CAMK2G,TJP1,ARHGAP19,PDE3B,CCSER2,PKN2,DPYSL5,PTCH1,CADM2,PRDM2,KCNA1,PTPRD,KCNA6,DLG2,WIPF2,EFNA3" MicroRNA hsa-miR-133b:TargetScan hsa-miR-133b TargetScan 1.88E-14 1.02E-10 6.00E-14 5.50E-13 33 487 "EYA1,FAM43B,ADARB2,FGF1,LRRC7,FOXG1,ANK2,NTNG1,PDE8B,NRG3,CPLX2,BCL2L2,NFIA,MYRF,GPM6A,PTBP2,PSD3,GRIA2,RFFL,PDE1C,PFKFB3,DLGAP3,CELF5,NCAN,RBPJ,PROX1,ELMO1,PTPRD,KCNA6,KCND3,PTPRZ1,DLG2,ARHGAP12" MicroRNA hsa-miR-133a-3p.2:TargetScan hsa-miR-133a-3p.2 TargetScan 1.88E-14 1.02E-10 6.00E-14 5.50E-13 33 487 "EYA1,FAM43B,ADARB2,FGF1,LRRC7,FOXG1,ANK2,NTNG1,PDE8B,NRG3,CPLX2,BCL2L2,NFIA,MYRF,GPM6A,PTBP2,PSD3,GRIA2,RFFL,PDE1C,PFKFB3,DLGAP3,CELF5,NCAN,RBPJ,PROX1,ELMO1,PTPRD,KCNA6,KCND3,PTPRZ1,DLG2,ARHGAP12" MicroRNA hsa-miR-299-3p:mirSVR_highEffct hsa-miR-299-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.90E-14 1.03E-10 6.06E-14 5.56E-13 37 614 "RABEPK,RTKN,KLHL32,ERMN,GPR158,C1orf61,ANK3,USP28,ITSN1,APC,CLSTN1,SLC1A7,MADD,MSR1,TMEM108,MYT1L,SOX5,COLGALT2,ABCC8,TBX15,CACNB2,LINC00839,P2RX7,TPM4,HMGB1,DLGAP3,NRXN1,BTF3L4,USP54,HP1BP3,KCNMA1,PLEKHB2,FAM13C,RFX4,SYT15,EPB41L2,BAALC" MicroRNA hsa-miR-4317:mirSVR_highEffct hsa-miR-4317:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-14 1.07E-10 6.25E-14 5.74E-13 35 550 "ABAT,SYT9,DUSP27,KLHL32,KIAA1109,ASIC4,UNC79,FOXM1,SH3GL2,MSRA,DACH2,SLCO1A2,SORCS3,ARHGEF7,PCDH11X,CAMTA1,ACSL6,CAMK2G,GRIA1,GRIA2,GRIA4,LINC01102,CAMKV,DNAJC12,MFSD4A,ATRNL1,BRINP3,SYTL2,PMEPA1,PTPRO,PCDH15,DTNA,SLC6A15,SYT15,FGFBP3" MicroRNA hsa-miR-1826:PITA hsa-miR-1826:PITA_TOP PITA 2.02E-14 1.09E-10 6.41E-14 5.88E-13 22 197 "GALNT13,WAC,NLGN4X,SCN3A,SEMA6A,DOCK10,AQP4,MYT1L,DNER,NPAS3,GANAB,DCLK1,PDYN,NEGR1,SPATA6,EDRF1,CSDE1,MAGI2,SNX27,DLG2,JMJD1C,EPB41L2" MicroRNA hsa-miR-133a:PITA hsa-miR-133a:PITA_TOP PITA 2.11E-14 1.14E-10 6.70E-14 6.15E-13 24 243 "SNX30,FGF1,LRRC7,SH3GL2,NTNG1,ST3GAL3,SLC8A2,BCL2L2,NKX2-2,GPM6A,PTBP2,RFFL,DLGAP3,RIMS4,RBPJ,ZC3H11A,KCNA1,PTPRD,PTPRO,PTPRZ1,DLG2,WIPF2,SFXN5,ARHGAP12" MicroRNA hsa-miR-452-5p:TargetScan hsa-miR-452-5p TargetScan 2.11E-14 1.14E-10 6.70E-14 6.15E-13 24 243 "EPS8,RIMKLA,LDLRAD3,ADARB2,GALNT13,ADD3,HPCAL4,ANK2,C11orf87,CNTN2,CAMK2G,GRM3,DCLK1,BTF3L4,PPP3CB,PKN2,ANKS1B,HP1BP3,KCNN3,RAD52,C12orf4,SEC61A2,ABI2,EPB41L1" MicroRNA hsa-miR-892c-3p:TargetScan hsa-miR-892c-3p TargetScan 2.11E-14 1.14E-10 6.70E-14 6.15E-13 24 243 "EPS8,RIMKLA,LDLRAD3,ADARB2,GALNT13,ADD3,HPCAL4,ANK2,C11orf87,CNTN2,CAMK2G,GRM3,DCLK1,BTF3L4,PPP3CB,PKN2,ANKS1B,HP1BP3,KCNN3,RAD52,C12orf4,SEC61A2,ABI2,EPB41L1" MicroRNA hsa-miR-133b:PITA hsa-miR-133b:PITA_TOP PITA 2.11E-14 1.14E-10 6.70E-14 6.15E-13 24 243 "SNX30,FGF1,LRRC7,SH3GL2,NTNG1,ST3GAL3,SLC8A2,BCL2L2,NKX2-2,GPM6A,PTBP2,RFFL,DLGAP3,RIMS4,RBPJ,ZC3H11A,KCNA1,PTPRD,PTPRO,PTPRZ1,DLG2,WIPF2,SFXN5,ARHGAP12" MicroRNA hsa-miR-143:mirSVR_highEffct hsa-miR-143:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.14E-14 1.16E-10 6.77E-14 6.21E-13 53 1205 "ACTN2,ADD3,HOGA1,FGF1,ELMOD1,FOXG1,SELL,ERICH3,PKP4,SLC6A9,GABBR1,AHCYL1,NCAM1,ZNF638,NODAL,CACNA1A,PRUNE2,PTBP2,VSTM2A,INA,MAEL,PC,DCLK1,TPM3,PDE1C,PDYN,BEST3,CASC2,ZBED5,DNAJC12,MEAF6,COL9A2,NSD2,CHD1L,RNF14,PPP2R5C,OSBPL3,ATRNL1,PLD5,USP54,CTNND1,NRSN1,DNAJC6,BDNF-AS,CADM2,ELMO1,PTPRD,KCNC1,KCNK2,KCNMA1,CAMK1G,RFX4,INSYN2" MicroRNA hsa-miR-1256:mirSVR_highEffct hsa-miR-1256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.21E-14 1.20E-10 7.00E-14 6.42E-13 37 617 "LRRC7,FOXG1,ITSN1,API5,AQP4,CCDC88A,CAPRIN2,MTR,SMARCE1,SOX5,CAB39,ARPP21,STOX1,C1QC,UNC5D,ANO4,PRUNE2,NUMA1,RFFL,GRIK2,PCDH9,PCSK2,PDE1C,PRMT8,HMGB1,SNCAIP,VCAN,RBPJ,CTNND1,MASP1,PTHLH,AK5,TMEM255A,DPP6,DTNA,SLC6A15,RGS7" MicroRNA hsa-miR-525-3p:mirSVR_lowEffct hsa-miR-525-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.23E-14 1.21E-10 7.04E-14 6.46E-13 31 430 "PRR5L,ADD3,TOMM40L,LRRC7,PDZD4,SEMA6C,ANK3,URGCP,SORCS3,B3GAT1,ILDR2,ZSWIM8,AHCYL1,AJAP1,CACNB2,EML4,VXN,GRID1,CCKBR,LINC00839,PADI2,CHGA,CHRM1,ANLN,PLXNB3,PPP2R5C,TOX,MAGI2,SRGAP3,KCNJ10,SLC25A48" MicroRNA hsa-miR-431*:mirSVR_lowEffct hsa-miR-431*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.24E-14 1.22E-10 7.10E-14 6.51E-13 29 373 "TTYH1,ATAT1,ADAR,SLC44A5,NTNG1,CACHD1,ST3GAL3,BCL2L2,NDUFA5,GPR162,GLS,NHLH1,NUDT21,CECR2,VXN,DAAM2,CDK11B,ADGRG1,ASIC3,FADS2,SNCAIP,FAM131B,PSMD13,PTPRE,RAP1GAP,RFX4,ZNF248,ABI2,RAVER2" MicroRNA hsa-miR-548k:PITA hsa-miR-548k:PITA_TOP PITA 2.25E-14 1.22E-10 7.12E-14 6.53E-13 34 521 "RTN3,EYA1,CSMD2,RTN1,ADCY2,PKP4,MAGI3,CCDC88A,CSPG5,PALLD,MYT1L,CLASP2,SYT4,CAMTA1,CAMSAP2,GPM6A,GRIA2,TMEM257,ZFP91,LGI1,TPD52,KIAA1549L,TJP2,CELF5,TENM4,PPP3CB,CTNND1,PTPRD,KCNK2,GNE,FAM13C,PAK5,ELAVL3,TMEM100" MicroRNA hsa-miR-891b:PITA hsa-miR-891b:PITA_TOP PITA 2.27E-14 1.23E-10 7.18E-14 6.58E-13 25 268 "NLGN1,API5,RUFY2,SLC8A2,CCDC88A,DKK3,MYT1L,NMNAT2,KIF1B,NELL1,CAMSAP2,BTRC,TCF12,CDC42,HMGB1,BTF3L4,PPP3CB,OSBPL3,TOX,SYTL2,PTPRD,KCNJ10,DLG2,RBM12,SH3GLB1" MicroRNA hsa-miR-4324:mirSVR_highEffct hsa-miR-4324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.29E-14 1.24E-10 7.23E-14 6.63E-13 38 651 "LGR4,MEG3,NDRG2,TOMM40L,ASIC4,SELL,ERICH3,SH3GL2,APBA2,BCAS1,API5,MIER1,SLC14A1,ATM,B3GALT2,SOX5,ZNF638,CAMSAP2,UNC5D,CACNA1E,EML4,GRIA2,CDH8,MAGI1,CASC2,CADM1,SULT4A1,TENM4,MAPK8,PLPPR5,OCIAD1,RABGAP1L,PCDH15,KCNN3,WIPF2,FAM66C,RASGRF1,RGS10" MicroRNA hsa-miR-224:PITA hsa-miR-224:PITA_TOP PITA 2.32E-14 1.26E-10 7.33E-14 6.72E-13 28 346 "ACLY,RBM10,ADAR,GPR158,FGF14,ANK3,ITSN1,APBA2,RUFY2,MYT1L,SEPT3,BTRC,GPM6A,REPS2,CDC42,TPM3,FNDC5,PFKFB3,PRRX1,POU3F2,MED1,WBP1L,KCNK2,KCNMA1,SLC17A6,RTN4,EFNA3,SLC4A10" MicroRNA hsa-miR-378*:mirSVR_highEffct hsa-miR-378*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.41E-14 1.31E-10 7.60E-14 6.98E-13 36 586 "SYT9,SORCS1,ERMN,FCGR1A,GPR158,LINC00461,FGR,MOBP,CCDC80,GPAM,NLGN1,SLC1A6,CCDC88A,B4GALNT1,NPAS3,LMO3,COLGALT2,NDUFA5,KIRREL3,AIFM1,DAAM2,PDE1C,RGS6,DZIP3,USP54,KCNJ9,DNAH9,FAM66C,ATG16L1,C12orf4,DTNA,ABCC9,INSYN2,VANGL2,RPE65,TMEM100" MicroRNA hsa-miR-1915*:mirSVR_highEffct hsa-miR-1915*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-14 1.31E-10 7.62E-14 6.99E-13 32 461 "TMEM74,ATAT1,SORCS1,PPFIA1,SHTN1,PAAF1,MSR1,BRINP2,SMARCE1,USP33,KIF1B,NFASC,ADHFE1,SLCO1C1,SYT4,CAMTA1,NODAL,ADGRL3,AZIN2,GRIA2,ZDHHC22,TLX1,ZFYVE9,KIAA1549L,PRRX1,MED1,ATRNL1,KCNJ9,PCDH15,HS3ST4,RLBP1,FGFBP3" MicroRNA "ATGTACA,MIR-493:MSigDB" "ATGTACA,MIR-493:MSigDB" MSigDB 2.45E-14 1.33E-10 7.71E-14 7.07E-13 26 294 "EYA1,ARID1A,NLGN1,MADD,ARHGAP5,SORCS3,KIF1B,ADGRL3,ANO4,TJP1,NLGN3,NXPH1,PPP2R5C,PPP3CB,CTNND1,CTNND2,RIMS3,PLPPR5,ZNF385B,LRRTM3,AK5,KCNMA1,NAV2,DLG2,EFNA3,RBM12" MicroRNA hsa-miR-485-3p:TargetScan hsa-miR-485-3p TargetScan 2.45E-14 1.33E-10 7.72E-14 7.08E-13 27 320 "ARID1A,KLHL32,GRAMD1B,ANK3,GAS7,KIF21B,CPLX2,FAM168A,NFIA,GRID1,GRIK3,AIFM1,REPS2,HPSE2,NRXN1,FTO,NXPH1,PROX1,ANKS1B,CEP170,MAGI2,PTPRD,NTM,PEX5,HS3ST4,RNF220,EPB41L1" MicroRNA hsa-miR-539-3p:TargetScan hsa-miR-539-3p TargetScan 2.45E-14 1.33E-10 7.72E-14 7.08E-13 27 320 "ARID1A,KLHL32,GRAMD1B,ANK3,GAS7,KIF21B,CPLX2,FAM168A,NFIA,GRID1,GRIK3,AIFM1,REPS2,HPSE2,NRXN1,FTO,NXPH1,PROX1,ANKS1B,CEP170,MAGI2,PTPRD,NTM,PEX5,HS3ST4,RNF220,EPB41L1" MicroRNA hsa-miR-3201:mirSVR_highEffct hsa-miR-3201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.54E-14 1.37E-10 7.98E-14 7.32E-13 36 587 "PRR5L,SLITRK1,LRRTM4,LRRC7,C1orf61,SLITRK3,ST3GAL3,SLC8A3,CADPS,NRG3,DKK3,AHCYL1,C11orf87,OLR1,PCDH9,ARHGAP19,LGI1,PRMT8,HMGB1,TMEFF2,CADM1,OPALIN,FTO,PPP3CB,PTHLH,MAGI2,KCNA4,NTM,RABGAP1L,KCNK2,RAB5B,SUSD4,FAM135B,RAVER2,SLC4A10,OLIG2" MicroRNA hsa-miR-26a-1*:mirSVR_highEffct hsa-miR-26a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-14 1.51E-10 8.76E-14 8.04E-13 57 1377 "RABEPK,LOC100128239,RTN3,EXTL1,ACTN2,MEG3,ADGRV1,MDM4,SORCS1,GRAMD1B,SCN3A,SOX6,USP28,NTNG1,MAGI3,SCG3,SLCO1A2,SMARCE1,ATM,MYT1L,NAP1L2,NCAM1,LMO3,PCDH11X,ZNF638,CAMSAP2,TBX15,WSCD1,CACNA1E,PRLHR,GRIA4,OLR1,OPCML,TNS1,TPD52,ANO5,FLRT1,PRRX1,SLC36A4,CHD1L,CRLS1,ATRNL1,NCAN,DOCK7,DZIP3,USP54,CTNND2,PUM1,ANKS1B,DLG2,KLRC2,SLC17A6,FAM66C,C12orf4,CRTAC1,JMJD1C,RPRD1A" MicroRNA hsa-miR-125b-1*:mirSVR_lowEffct hsa-miR-125b-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-14 1.60E-10 9.26E-14 8.49E-13 29 377 "SDE2,SRARP,NTNG1,NLGN1,CLSTN1,ASCL1,KIF1B,SEPT3,GNG4,ZEB1,GRIA2,PCDH8,BEST3,PFKFB3,CASC2,MEAF6,CELF5,MED1,ZNF385B,SYNC,PRDM2,COPS7A,OLFM3,RABGAP1L,PARP11,DTNA,RLBP1,ARHGAP12,YY1AP1" MicroRNA hsa-miR-2116*:mirSVR_highEffct hsa-miR-2116*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.05E-14 1.65E-10 9.57E-14 8.78E-13 38 657 "MDM4,NDRG2,KLHL32,GALNT13,KIAA1109,ITSN1,PAAF1,SPHKAP,SORCS3,ENKUR,KIF1B,FXYD6,NPAS3,ZNF302,ADGRL3,TMEM136,NUMA1,GRIA2,MAEL,MAGI1,PLEKHB1,TLX1,NRXN1,CRLS1,PPP3CB,MICAL2,RBPJ,PRKACB,DZIP3,NRSN1,PROX1,GON4L,PLPPR1,CADM2,SMG7,PLPPR4,JMJD1C,SLC4A10" MicroRNA hsa-miR-217:TargetScan hsa-miR-217 TargetScan 3.08E-14 1.67E-10 9.65E-14 8.85E-13 27 323 "ACER3,RIMKLA,CSMD2,ARID1A,ELMOD1,FOXG1,ANK3,PPM1E,CACHD1,NLGN1,DACH2,NPAS3,NCAM1,NEUROD1,GPM6A,GRIK2,PCDH8,ANLN,FTO,ATCAY,MED1,PROX1,LRRTM3,KIF2A,ABCC9,JMJD1C,ARHGAP12" MicroRNA hsa-miR-765:Functional MTI Functional MTI miRTarbase 3.09E-14 1.67E-10 9.69E-14 8.89E-13 28 350 "DPF1,ARID1A,RPH3A,RAP1GAP2,FAM168A,ASTN2,GNG3,BTRC,PSD3,ZFP91,TPM3,BEST3,PFKFB3,NEGR1,SPATA6,PACSIN1,CRMP1,RGS6,KIAA0513,KCND3,NAV2,RAB5B,DNM2,PARP11,SSPN,CACNG7,EFNA3,EPB41L1" MicroRNA hsa-miR-500b:mirSVR_highEffct hsa-miR-500b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.12E-14 1.69E-10 9.78E-14 8.97E-13 37 624 "ADGRV1,ATAT1,NLGN4X,LRRTM4,ERICH3,SGIP1,ANK3,ITSN1,PAAF1,AQP4,ZNF365,ALDH4A1,NRG3,USP33,CASTOR3,ANO4,AKNA,RFFL,GPR88,NMT2,RNF14,KCNT2,PRKACB,SYNC,PSMD13,BDNF-AS,PTHLH,OCIAD1,PTPRD,PTPRE,RABGAP1L,KCNMA1,DNM2,ABCC9,RFX4,SEC61A2,BAALC" MicroRNA hsa-miR-4294:mirSVR_highEffct hsa-miR-4294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.27E-14 1.77E-10 1.02E-13 9.40E-13 36 592 "DUSP27,ADGRV1,ATAT1,KCNIP2,PLEKHG5,ERMN,GRAMD1B,ELMOD1,MOG,MT3,SLC14A1,TAGLN3,SNAP25,SNCB,TNIK,NELL1,KLHL4,ZEB1,CAMK2G,GUCY1A2,JAM2,SERPINE2,CADM1,P2RY12,SF1,RGS6,PLPP4,USP54,CTNND1,SPIRE1,ELMO1,WIPF2,SUSD4,RASGRF1,GNE,RCAN2" MicroRNA hsa-miR-338-3p:mirSVR_highEffct hsa-miR-338-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.29E-14 1.78E-10 1.03E-13 9.44E-13 43 834 "RTN1,ERMN,LRRTM4,LRRC7,ERICH3,SLITRK3,LRRC4C,ARFGAP1,MYT1L,LMO3,CLASP2,DCAF5,ADHFE1,NEUROD1,SLCO1C1,DCLK2,GNAS,CACNB2,EML4,GRIA2,GRIA4,LINC00839,SEZ6L,MAGI1,HMGB1,C11orf49,MEAF6,CP,LRRTM3,PTCH1,JAKMIP2,CADM2,SRGAP3,ABI1,DTNA,ZYG11B,RFX4,RGS7,FAM135B,ARHGEF10L,SEC61A2,ABI2,CBLN2" MicroRNA hsa-miR-1293:mirSVR_highEffct hsa-miR-1293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.30E-14 1.79E-10 1.03E-13 9.48E-13 34 528 "SERPINA3,MDM4,SORCS1,ANK3,ITSN1,SLITRK3,ZNF365,RPH3A,SLC1A7,PALLD,WDTC1,SOX5,TTLL9,NELL1,VAMP1,SYT4,GNAS,TBX15,PRUNE2,VSTM2A,INA,CELF3,MAEL,REPS2,CDC42,NLGN3,PLD5,KCNJ10,DLG2,SLC25A48,ZYG11B,RERGL,ABI2,SEZ6" MicroRNA hsa-miR-324-5p:mirSVR_highEffct hsa-miR-324-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.56E-14 1.93E-10 1.11E-13 1.02E-12 28 352 "SYT9,CDC42BPA,ITSN1,PKP4,API5,MIER1,MT3,RCOR3,ATM,NELL1,SEPT3,GRIA2,CCKBR,CRB1,TMEM257,LGI1,TMEFF2,CAMKV,CCSER2,CNTN1,CNRIP1,PRKCG,PTPRD,PTPRE,RABGAP1L,DNAH9,RAD52,CBLN2" MicroRNA hsa-miR-650:mirSVR_highEffct hsa-miR-650:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.71E-14 2.01E-10 1.16E-13 1.06E-12 40 730 "SYT9,WLS,ADCY2,FCGR1A,SLC8A3,EIF4G3,SOX10,JPH4,B4GALNT1,BCL2L2,ABCC8,GLS,VAMP1,GNAS,CDK5R2,CACNA1E,NUMA1,USP2,HEPACAM,NMT2,CCSER2,MICAL2,VCAN,DZIP3,IGSF1,PLPPR1,PRDM2,ZC3H11A,PTPRE,SV2A,DPP6,DTNA,PAK5,SLC6A15,ZYG11B,JMJD1C,RGS7,VANGL2,SLC4A10,TMEM100" MicroRNA hsa-miR-133a:mirSVR_highEffct hsa-miR-133a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.79E-14 2.05E-10 1.18E-13 1.09E-12 37 628 "CSMD2,SNX30,LRRC7,SH3GL2,ST3GAL3,PDE8B,ARPP21,TTLL9,ALDH1L1,GPM6A,PTBP2,VXN,GRIA4,RFFL,TPM3,TPM4,PDE1C,HMGB1,BEST1,CNRIP1,NCAN,RBPJ,CMTM5,ZC3H11A,PTPRD,PTPRO,PTPRZ1,SV2A,PCDH15,KCNMA1,DLG2,DPP6,RALGDS,C12orf4,DBX2,VWA5A,ARHGAP12" MicroRNA hsa-miR-133b:mirSVR_highEffct hsa-miR-133b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.79E-14 2.05E-10 1.18E-13 1.09E-12 37 628 "CSMD2,SNX30,LRRC7,SH3GL2,ST3GAL3,PDE8B,ARPP21,TTLL9,ALDH1L1,GPM6A,PTBP2,VXN,GRIA4,RFFL,TPM3,TPM4,PDE1C,HMGB1,BEST1,CNRIP1,NCAN,RBPJ,CMTM5,ZC3H11A,PTPRD,PTPRO,PTPRZ1,SV2A,PCDH15,KCNMA1,DLG2,DPP6,RALGDS,C12orf4,DBX2,VWA5A,ARHGAP12" MicroRNA hsa-miR-3172:mirSVR_highEffct hsa-miR-3172:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.87E-14 2.09E-10 1.21E-13 1.11E-12 43 838 "RABEPK,ACER3,MAP6,ATAT1,CLIP1,ADCY2,DSCAML1,SORCS1,FGF1,FHL1,MOG,MAGI3,DGKZ,CACHD1,MSRA,CCDC88A,SLC14A1,B4GALNT1,SEPT3,PCDH11X,CAMK2G,VSTM2A,ATP13A2,TNFRSF1B,SEZ6L,PCSK2,ZMYND8,CASC2,JAM2,SLC22A6,NSD2,NKAIN4,RBPJ,EDRF1,TOMM20,PSMD13,PTAFR,CNIH3,PTPRD,KCNJ10,BSDC1,ELAVL4,YY1AP1" MicroRNA hsa-miR-876-3p:PITA hsa-miR-876-3p:PITA_TOP PITA 4.12E-14 2.23E-10 1.29E-13 1.18E-12 18 123 "ARID1A,LRRTM4,SEMA6A,SNAP25,FAM168A,VAMP1,CAMK2G,SYT6,GRIA1,GDAP1L1,UBTF,PRKCZ,PHYHIP,OLFM3,PTPRD,DLG2,WIPF2,ABI2" MicroRNA hsa-miR-1185:mirSVR_highEffct hsa-miR-1185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.19E-14 2.27E-10 1.31E-13 1.20E-12 39 698 "TTYH1,SDE2,ACTN2,CSMD3,SLC44A5,FGF14,FOXM1,SH3GL2,SYBU,NLGN1,CGREF1,ASPH,B3GAT1,ENKUR,FXYD6,CLASP2,LUZP2,CAMTA1,CACNB2,TCF12,ZNF384,HPSE2,PMP2,BTF3L4,MFSD4A,SNCAIP,PLPP4,HES5,SYTL2,GON4L,PRDM2,CEP170,MAGI2,OLFM3,C1orf109,TMCC2,PARP11,DPP6,FGFBP3" MicroRNA hsa-miR-3158:mirSVR_highEffct hsa-miR-3158:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.24E-14 2.29E-10 1.32E-13 1.21E-12 38 664 "MDM4,F3,LRRTM4,SFPQ,ANK3,ITSN1,ARFGAP2,SLC8A3,SLC14A1,SLIT1,BRINP2,SMARCE1,ATM,NRG3,SOX5,NPAS3,NFASC,NELL1,GRIA2,GPR88,PAX6,HPS5,LGI1,PDYN,FNDC5,A2ML1,BEST1,SPATA6,CHD1L,CA10,HP1BP3,PTPRE,KCNC1,KCNMA1,SNX27,RTN4,L1CAM,RFX5" MicroRNA hsa-miR-608:mirSVR_highEffct hsa-miR-608:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.24E-14 2.29E-10 1.32E-13 1.21E-12 38 664 "DSCAML1,TRIM46,ERICH3,ITSN1,ZCCHC17,SLC8A3,ASCL1,B3GAT1,SNAP25,SNCB,PALLD,GABBR1,B4GALNT1,GPR162,VAMP1,GNAS,PSRC1,PRUNE2,NPPA,NRGN,INA,SEZ6L,ZNF384,PRMT8,ZMYND8,PFKFB3,HNRNPK,FADS2,PMP2,NRSN1,KLK6,PSD,COPS7A,PCDH15,KCNMA1,NAV2,RTN4,PRRT4" MicroRNA hsa-miR-1228:mirSVR_highEffct hsa-miR-1228:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.42E-14 2.39E-10 1.38E-13 1.26E-12 33 502 "EYA1,ARID1A,CLIP1,LRRTM4,LRRC7,FOXG1,PKP4,BCAS1,SLC2A5,MSRA,DKK3,GAD2,DCAF5,RGL1,OS9,SYT4,DCLK2,CACNA1E,TJP1,PAX6,HPS5,PCDH9,CDH10,PFKFB3,CADM1,NRXN1,RNF14,PRKACB,EDRF1,KCNA4,ZYG11B,JMJD1C,EN2" MicroRNA hsa-miR-765:PITA hsa-miR-765:PITA_TOP PITA 4.57E-14 2.47E-10 1.42E-13 1.30E-12 21 183 "ASIC1,ARID1A,SEMA6A,SEPT3,VAMP1,BTRC,CAMK2G,OMG,GUCY1A2,CELF3,DCLK1,TPM3,CADM1,PRRX1,PNKD,CTNND1,MAPK10,KCNA1,KCNJ11,DLG3,EFNA3" MicroRNA hsa-miR-340*:mirSVR_lowEffct hsa-miR-340*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.60E-14 2.49E-10 1.43E-13 1.31E-12 42 806 "LOC100128239,SYT9,ADORA1,ITSN1,PKP4,KBTBD12,ATM,ARPP21,FXYD6,NELL1,LUZP2,CAMTA1,GNG4,TMEM136,PRLHR,GRIA4,RFFL,GRIN1,CD81,TPM3,CADM1,ZFYVE9,PIK3CD,CPT1C,A2ML1,TJP2,FAM181B,CELF5,ACBD5,PHACTR3,PUM1,TUBB2B,CNIH3,PRDM2,HP1BP3,PTPRE,SRGAP3,GNE,PHC2,SEC61A2,GPR61,EPB41" MicroRNA hsa-miR-609:mirSVR_highEffct hsa-miR-609:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.65E-14 2.52E-10 1.45E-13 1.33E-12 31 442 "ACLY,MRVI1,ARID1A,SORCS1,LCNL1,GPR158,ITSN1,CCDC88A,SMARCE1,ARHGEF7,GRIK2,CCKBR,GUCY1A1,HPS5,TPD52,HNRNPK,NRXN2,TJP2,BEST1,PLD5,PLPPR5,DNAJC6,OLFM3,SLC25A48,GOPC,BSDC1,RFX4,ZNF248,SSPN,CBLN2,OLIG2" MicroRNA hsa-miR-188-3p:PITA hsa-miR-188-3p:PITA_TOP PITA 4.67E-14 2.53E-10 1.45E-13 1.33E-12 23 228 "LGR4,WAC,RCOR3,PCDH11X,ASTN2,PTBP2,CAMK2G,GRIA4,LGI1,ZNF384,NRXN2,CAMKV,MED1,TENM4,PSD,KCNA1,PTPRD,SRGAP3,WIPF2,ABI1,INSYN2,PHC2,PIANP" MicroRNA hsa-miR-422a:mirSVR_highEffct hsa-miR-422a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.99E-14 2.70E-10 1.55E-13 1.42E-12 42 808 "KCNIP2,RXRG,FABP7,SORCS1,SLC44A5,FCGR1A,FOXG1,CAPRIN2,SORCS3,EIF4G3,NCAM1,BCL2L2,NELL1,NEUROD1,GLS,GNAS,CAMTA1,GRIA4,GRIK2,TF,CDH8,LGI1,KIAA1549L,CAMKV,C11orf49,BEST1,PACSIN1,PRKACB,RAB39A,CADM2,PRTFDC1,STMN4,KCNJ10,KIF2A,DSCAM,CAMK1G,RFX4,ZNF248,RBM12,SH3GLB1,UEVLD,BAALC" MicroRNA hsa-miR-2277:mirSVR_lowEffct hsa-miR-2277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.31E-14 2.88E-10 1.65E-13 1.51E-12 37 635 "EPS8,ACER3,ACHE,SYT9,LDLRAD3,RTKN,SGIP1,ANK3,PPM1E,DOCK10,NTNG1,GPAM,SLC8A2,USP33,ADAM15,SYT4,ASTN2,CAMTA1,CAMSAP2,TCF7L2,ZEB1,AZIN2,GRIA2,GPR88,OLR1,CADM1,PLXNB3,CELF5,IFFO1,PTPRO,KCNK1,PCDH15,CAB39L,DTNA,RET,VWA5A,ELAVL4" MicroRNA hsa-miR-191:mirSVR_lowEffct hsa-miR-191:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.65E-14 3.06E-10 1.75E-13 1.61E-12 34 538 "CDHR1,RCSD1,LINC00461,SEMA6A,ITSN1,CACHD1,MIER1,TAGLN3,EIF4G3,ATP2B2,ZCCHC24,AJAP1,NFIA,ZNF638,MYRF,CDK5R2,PTBP2,GRIK2,MAEL,PCDH8,RBFOX2,CELF5,P2RY12,BRINP3,PSMD13,OLFM3,SRGAP3,RABGAP1L,ATG16L1,RASGRF1,FAM13C,PHC2,ABI2,ARHGAP12" MicroRNA hsa-miR-22:PITA hsa-miR-22:PITA_TOP PITA 6.15E-14 3.33E-10 1.91E-13 1.75E-12 24 255 "ACER3,ACLY,SYT9,SORCS1,TESK2,PDZD4,NTNG1,MEGF11,WDTC1,GPR162,CAMK2G,VXN,BRSK2,ZFP91,KCNK10,RBFOX2,CHGA,TUB,RIMS4,SMG7,SV2A,SNX27,RAB5B,EPB41L2" MicroRNA hsa-miR-330-5p:mirSVR_highEffct hsa-miR-330-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.55E-14 3.55E-10 2.03E-13 1.86E-12 40 743 "SYT9,KCNIP2,ADARB2,TOMM40L,FGF1,CDC42BPA,ITSN1,PKP4,MAGI3,CACHD1,PAAF1,ARFGAP2,TMEM108,ZSWIM8,ARPP21,NPAS3,ERBIN,ZNF638,PSRC1,TCF12,CRB1,CDH8,TPM3,PRMT8,SLC25A27,CHD1L,PPP3CB,MICAL2,OSBPL3,NCAN,BDNF-AS,C1orf109,NAV2,DLG3,NKAIN1,SLC25A48,SLC17A6,DBX2,BSDC1,ZNF248" MicroRNA hsa-miR-526b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-14 3.65E-10 2.08E-13 1.91E-12 37 640 "ATAT1,ADAR,F3,WAC,FOXRED2,DRAXIN,SESN3,RUFY2,CAPRIN2,SON,EMC1,SALL3,BCL2L2,SMOC1,LUZP2,WWC1,TCF7L2,MFSD2A,TPM4,HMGB1,ZFYVE9,BTF3L4,PRKACB,KIAA0513,CADM2,CEP170,CSDE1,OCIAD1,KCND3,RABGAP1L,WIPF2,RAB5B,SH3GLB1,ABI2,ARHGAP12,BSCL2,TMEM100" MicroRNA hsa-miR-211-5p:Functional MTI Functional MTI miRTarbase 6.91E-14 3.74E-10 2.13E-13 1.96E-12 27 334 "SRARP,ADCYAP1R1,TMEM156,ADORA3,ASIC4,BCAN,CACHD1,LRRC55,ZCCHC24,SMOC1,MYRF,TCF7L2,TCF12,CAMK2G,SYT6,PADI2,CDH8,SEZ6L,TMEFF2,PHKG1,SLC22A6,POU3F2,CHD5,PRDM2,KCNMA1,RAB5B,ZYG11B" MicroRNA hsa-miR-3157:mirSVR_highEffct hsa-miR-3157:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.31E-14 3.96E-10 2.26E-13 2.07E-12 44 891 "CDHR1,RTN3,ATAT1,WAC,FABP7,ERMN,TRIM46,SELL,ANK2,ITSN1,USP16,SLC8A3,SNAP25,ARPP21,NASP,ZNF638,SYT4,ROBO3,NRDC,PTBP2,VXN,VSTM2A,GRIK2,ZDHHC22,PCSK2,PDE1C,PDE3B,PRMT8,HNRNPK,CP,MICAL2,DOCK7,CTNND1,FGFR1OP2,HP1BP3,C1orf109,PCDH15,DLG2,PID1,PLEKHB2,GNE,FAM13C,ZYG11B,EPB41L1" MicroRNA hsa-miR-885-3p:mirSVR_lowEffct hsa-miR-885-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.56E-14 4.09E-10 2.33E-13 2.14E-12 41 782 "LGR4,MEG3,ADORA1,TMEM156,LINC00461,ASIC4,TRIM46,PKP4,ARFGAP1,RCOR3,GABBR1,ADAM15,ADGRB2,ADHFE1,ARHGEF7,GNAS,CAMK2A,LINC00839,LEFTY2,CELF3,CDC42,TNS1,PCDH9,LGI1,PFKFB3,CASC2,C11orf49,ATCAY,PPP2R5C,MICAL2,PLCH2,NRSN1,COPS7A,PEX5,RALGDS,L1CAM,CRTAC1,RFX4,EEF1A2,RNF220,ELAVL3" MicroRNA hsa-miR-615-3p:Functional MTI Functional MTI miRTarbase 7.90E-14 4.28E-10 2.44E-13 2.24E-12 44 893 "SDE2,ZFYVE27,RBM10,PLEKHG5,CDC7,CHST15,KIAA1109,SFPQ,USP28,APBA2,NMNAT2,SALL3,GART,GANAB,RHBDL3,GNAS,NRDC,ATP13A2,TJP1,ARHGAP19,TPM3,HNRNPK,ARHGAP22,ZFYVE9,CPT1C,NSD2,CHD5,PRKAB2,CTNND1,WBP1L,TUBB2B,PSMD13,SIRPA,RGMA,DLG3,KIF2A,RAB5B,DNM2,PLEKHB2,RALGDS,ATN1,BSDC1,FAM135B,RAVER2" MicroRNA hsa-miR-6785-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.96E-14 5.39E-10 3.07E-13 2.82E-12 42 825 "EMID1,ADAR,WAC,CCDC80,JAKMIP3,CLSTN1,SLC1A2,PKNOX2,DNAH17,KBTBD12,ZCCHC24,NKX6-2,TTLL9,NDUFA5,GNG4,NRGN,HAP1,CAMK2A,BEST3,SCRG1,TMPRSS5,PFKFB3,DLGAP3,CCSER2,BTF3L4,FAT3,MFSD4A,PTPA,DOCK7,DPYSL5,PHYHIP,TOMM20,BDNF-AS,PTPRE,NAV2,SNX27,DNAH9,RAB5B,PLEKHB2,PARP11,PHC2,ABI2" MicroRNA hsa-miR-6883-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.96E-14 5.39E-10 3.07E-13 2.82E-12 42 825 "EMID1,ADAR,WAC,CCDC80,JAKMIP3,CLSTN1,SLC1A2,PKNOX2,DNAH17,KBTBD12,ZCCHC24,NKX6-2,TTLL9,NDUFA5,GNG4,NRGN,HAP1,CAMK2A,BEST3,SCRG1,TMPRSS5,PFKFB3,DLGAP3,CCSER2,BTF3L4,FAT3,MFSD4A,PTPA,DOCK7,DPYSL5,PHYHIP,TOMM20,BDNF-AS,PTPRE,NAV2,SNX27,DNAH9,RAB5B,PLEKHB2,PARP11,PHC2,ABI2" MicroRNA hsa-miR-106b*:mirSVR_lowEffct hsa-miR-106b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-13 5.45E-10 3.10E-13 2.84E-12 34 549 "TMEM74,CSMD3,F3,AMPH,NTNG1,SLC8A3,SMARCE1,RCOR3,FYN,NCAM1,NCDN,GPM6B,CACNB2,TCF7L2,NRGN,CAMK2A,GRIA1,CYB561A3,HPCA,KIAA1549L,TJP2,BTF3L4,CRLS1,MICAL2,DZIP3,ECE2,BRINP3,KCNA4,PTPRO,KCNK2,KCNMA1,DPP6,DSCAM,JMJD1C" MicroRNA hsa-miR-202:mirSVR_highEffct hsa-miR-202:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-13 5.49E-10 3.12E-13 2.86E-12 38 683 "RABEPK,SDE2,ACER3,AMER2,FHL1,MOBP,DGKZ,AQP4,NAXD,SOX10,ILDR2,KIF1B,NPAS3,CASTOR3,CACNA1E,GRIA2,GRIA4,CCKBR,AIFM1,RBFOX2,ZNF384,CIART,HMGB1,MS4A7,ETNPPL,VCAN,SPIRE1,ZC3H11A,PTPRD,PTPRO,KIF2A,PLEKHB2,RASGRF1,NUP214,VANGL2,RBM12,RAVER2,PLEKHO1" MicroRNA hsa-miR-502-3p:PITA hsa-miR-502-3p:PITA_TOP PITA 1.01E-13 5.49E-10 3.12E-13 2.86E-12 20 169 "ADCY2,NLGN4X,SCN3A,NTNG1,SLC8A2,PTBP2,PSD3,GRIA2,TJP1,PCDH9,DCLK1,PDE3B,CADM1,CHD5,CTNND1,FAM131B,KIAA0408,CSDE1,KCNA1,ATL1" MicroRNA hsa-miR-3187:mirSVR_highEffct hsa-miR-3187:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-13 5.50E-10 3.13E-13 2.87E-12 36 615 "MAP6,TMEM74,CNTNAP3,FGF1,SH3GL2,APBA2,BCAS1,RUFY2,ERBIN,PCDH11X,ZNF638,NKX2-2,ANO4,VXN,VSTM2A,LINC00839,TLL2,RBFOX2,PDE1A,PRMT8,HPSE2,CASC2,CCSER2,OPALIN,CNTN1,PRRX1,VCAN,SDC3,CTNND2,CSDE1,PTPRZ1,SV2A,PCDH15,ZYG11B,ZNF248,SEZ6" MicroRNA hsa-let-7d*:mirSVR_lowEffct hsa-let-7d*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-13 5.57E-10 3.16E-13 2.90E-12 29 396 "PRR5L,MAP6,SYT9,EYA1,MDM4,SLITRK1,DOCK10,TACC2,RCOR3,BCL2L2,RGL1,NEUROD1,LRIT2,GRIA2,TGFBR3,CDC42,PCDH8,PDE2A,PDE3B,ACOT7,CCSER2,MEAF6,ATRNL1,DOCK7,MASP1,SYTL2,SRGAP3,SNX27,DTNA" MicroRNA hsa-miR-517c:mirSVR_lowEffct hsa-miR-517c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-13 5.93E-10 3.37E-13 3.09E-12 29 397 "CDHR1,RTN3,MOBP,TRIM46,PKP4,DGKZ,DACH2,RCOR3,NRG3,EIF4G3,WDTC1,NEUROD1,CACNB2,GPR19,BRSK2,LINC00839,CDK11B,SEMA5B,FTO,SLC36A4,POU3F2,PRKCZ,DNAJC6,JAKMIP2,PTPRO,PEX5,DTNA,ZYG11B,ATL1" MicroRNA hsa-miR-136-5p:TargetScan hsa-miR-136-5p TargetScan 1.12E-13 6.05E-10 3.43E-13 3.14E-12 24 262 "RIMKLA,MRVI1,ADCYAP1R1,LRRC55,NPAS3,GANAB,GNAS,GNG3,CNDP1,GPR26,PSD3,GRID1,KCNK10,PAX6,FAT3,OSBPL3,PLD5,ARHGEF4,OCIAD1,RABGAP1L,DLG3,RET,RPRD1A,PLEKHO1" MicroRNA hsa-miR-501-3p:PITA hsa-miR-501-3p:PITA_TOP PITA 1.14E-13 6.15E-10 3.48E-13 3.20E-12 20 170 "ADCY2,NLGN4X,SCN3A,NTNG1,SLC8A2,PTBP2,PSD3,GRIA2,TJP1,PCDH9,DCLK1,PDE3B,CADM1,CHD5,CTNND1,FAM131B,KIAA0408,CSDE1,KCNA1,ATL1" MicroRNA hsa-miR-378:mirSVR_highEffct hsa-miR-378:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.14E-13 6.19E-10 3.50E-13 3.21E-12 41 792 "KCNIP2,RXRG,FABP7,SORCS1,SLC44A5,FCGR1A,FOXG1,CAPRIN2,SORCS3,EIF4G3,NCAM1,BCL2L2,NEUROD1,ACSBG1,ARHGEF7,GLS,GNAS,CAMTA1,GRIA4,CDH8,SEZ6L,LGI1,HMGB1,KIAA1549L,CAMKV,C11orf49,BEST1,PRKACB,PLPP4,CTNND1,CADM2,PRTFDC1,PTPRD,KIF2A,HS3ST4,DSCAM,CAMK1G,ZNF248,RBM12,SH3GLB1,BAALC" MicroRNA hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA_TOP PITA 1.20E-13 6.49E-10 3.67E-13 3.37E-12 31 458 "SYT9,CLIP1,SLITRK1,SORCS1,NLGN4X,SOX6,SNAP25,NCAM1,LMO3,NEUROD1,BTRC,ATF7,CACNA1E,FBXL16,IGSF21,NRXN2,FAT3,NXPH1,POU3F2,PPP3CB,CHD5,CTNND2,PUM1,CEP170,STMN4,SNX27,RAB5B,PHC2,RBM12,EPB41L2,RASGRP2" MicroRNA hsa-miR-204-5p:Functional MTI Functional MTI miRTarbase 1.24E-13 6.74E-10 3.81E-13 3.50E-12 29 399 "SRARP,ADCYAP1R1,TMEM156,ADORA3,ASIC4,FOXM1,BCAN,CACHD1,LRRC55,ZCCHC24,BCL2L2,SMOC1,MYRF,TCF7L2,TCF12,CAMK2G,SYT6,CDC42,PADI2,CDH8,SEZ6L,TMEFF2,PHKG1,SLC22A6,CHD5,PRDM2,CSDE1,RAB5B,ZYG11B" MicroRNA hsa-miR-764:mirSVR_highEffct hsa-miR-764:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-13 7.04E-10 3.98E-13 3.65E-12 34 554 "ATAT1,CLIP1,WAC,SLC44A5,TOMM40L,AGT,ITSN1,RUFY2,FYN,MEGF11,SOX5,GAD2,ZNF302,ARHGEF7,ZEB1,TJP1,AIFM1,CD81,PCDH8,PDYN,P2RY12,PACSIN1,PTPA,SNCAIP,NCAN,MAPK10,PRDM2,SRGAP3,PEX5,DTNA,JMJD1C,RPRD1A,RCAN2,BAALC" MicroRNA hsa-miR-1276:PITA hsa-miR-1276:PITA_TOP PITA 1.31E-13 7.08E-10 4.00E-13 3.67E-12 27 343 "LRRTM4,LRRC7,SEMA6A,AMPH,PPM1E,APC,SORBS1,ATP1A3,AHCYL1,NFASC,CAMTA1,GRID1,ZFP91,HNRNPK,NXPH1,PPP2R5C,CTNND1,CTNND2,ITGAV,CADM2,PTPRD,SMG7,KCNK2,WIPF2,ST8SIA3,RNF220,EN2" MicroRNA hsa-miR-29b:mirSVR_highEffct hsa-miR-29b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.35E-13 7.31E-10 4.13E-13 3.79E-12 52 1222 "MAP6,RBM10,RTN3,ATAT1,ADD3,CDC7,GRAMD1B,LINC00461,SFPQ,APC,GPAM,BCAS1,SHTN1,CAPRIN2,ASPH,BRINP2,DKK3,ARPP21,KIF1B,ADGRB2,NAP1L2,NPAS3,NASP,NCAM1,ADHFE1,MMD2,PTBP2,EML4,VSTM2A,TF,HRH3,FNDC5,MS4A7,HNRNPK,CCSER2,BEST1,POU3F2,CRMP1,PRKAB2,IGSF1,MASP1,DPYSL5,PLPPR5,LRRTM3,DNAJC6,PTHLH,SV2A,KCNJ11,NAV2,SH3GLB1,ABI2,FGFBP3" MicroRNA hsa-miR-4288:mirSVR_highEffct hsa-miR-4288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-13 7.50E-10 4.23E-13 3.88E-12 38 690 "SERPINA3,SYT9,CHST15,LRRTM4,ERICH3,ANK2,USP28,ITSN1,SORBS1,CACHD1,LRRC4C,SORCS3,LMO3,RCOR2,PHLDB1,ZNF638,ADGRL3,PTPN5,MAGI1,CHRM1,NXPH1,SNCAIP,VCAN,RAB39A,MAPK10,MASP1,PLPPR5,PTHLH,OCIAD1,PTPRE,NTM,FAM66C,FAM13C,SLC6A15,ZYG11B,RFX4,RPRD1A,EPB41L1" MicroRNA hsa-miR-1280:mirSVR_lowEffct hsa-miR-1280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-13 7.56E-10 4.26E-13 3.91E-12 28 372 "RABEPK,RTN1,PNMA8B,STK32C,PAAF1,MIER1,CAPRIN2,ARPP21,ADAM15,KIF1B,ALDH1L1,KIRREL3,AJAP1,MLC1,TMEM151B,ZDHHC22,TNR,NRXN2,UBTF,CPT1C,SLC25A27,CTNND1,HES5,TOMM20,PSMD13,PRDM2,STMN4,DNAH9" MicroRNA hsa-miR-149-3p:Functional MTI Functional MTI miRTarbase 1.42E-13 7.71E-10 4.35E-13 3.99E-12 42 834 "EMID1,ADAR,WAC,CCDC80,JAKMIP3,CLSTN1,SLC1A2,PKNOX2,DNAH17,KBTBD12,ZCCHC24,NKX6-2,TTLL9,NDUFA5,GNG4,NRGN,HAP1,CAMK2A,BEST3,SCRG1,TMPRSS5,PFKFB3,DLGAP3,CCSER2,BTF3L4,FAT3,MFSD4A,PTPA,DOCK7,DPYSL5,PHYHIP,TOMM20,BDNF-AS,PTPRE,NAV2,SNX27,DNAH9,RAB5B,PLEKHB2,PARP11,PHC2,ABI2" MicroRNA "CTTTGCA,MIR-527:MSigDB" "CTTTGCA,MIR-527:MSigDB" MSigDB 1.49E-13 8.08E-10 4.55E-13 4.18E-12 22 217 "KCNIP2,ZCCHC17,API5,KIF1B,RAP1GAP2,NFASC,TBX15,CACNA1E,TCF12,HAP1,CAMK2A,PAX6,DCLK1,LGI1,PUM1,PMEPA1,SV2A,SRGAP3,KCNMA1,DSCAM,PIANP,EPB41L1" MicroRNA hsa-miR-2861:mirSVR_highEffct hsa-miR-2861:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-13 8.14E-10 4.58E-13 4.20E-12 29 402 "SERPINA3,ATAT1,SORCS1,ITSN1,SHTN1,ZNF365,SLC1A7,SMARCE1,SON,ILDR2,SALL3,ALDH1L1,ADHFE1,ABCC8,PCDHGA3,AKNA,GRIK2,LINC00839,MAEL,SLC25A27,COL9A2,KIAA1755,WBP1L,SIRPA,PTPRD,HS3ST4,DPP6,RASGRP2,UEVLD" MicroRNA hsa-miR-670-3p:TargetScan hsa-miR-670-3p TargetScan 1.50E-13 8.14E-10 4.58E-13 4.20E-12 29 402 "MDM4,AMER2,MOG,ANK3,PKP4,NRG3,DCAF5,FAM168A,NFIA,OS9,CNTN2,FBXL16,CELF3,RBFOX2,MAGI1,HMGB1,HNRNPK,NRXN2,PRRX1,FAT3,RBPJ,PRKACB,SDC3,LRRTM3,LRP8,KCND3,KCNK1,KCNN3,RTN4" MicroRNA "TCTCTCC,MIR-185:MSigDB" "TCTCTCC,MIR-185:MSigDB" MSigDB 1.52E-13 8.25E-10 4.64E-13 4.25E-12 17 114 "ATAT1,ARID1A,ATP1A3,KIF1B,NFASC,PHLDB1,ASTN2,TCF12,TJP1,CDC42,MAGI1,SF1,PHYHIP,CA10,PTPRE,KCNN3,PAK5" MicroRNA hsa-miR-512-3p:PITA hsa-miR-512-3p:PITA_TOP PITA 1.56E-13 8.43E-10 4.74E-13 4.35E-12 24 266 "SYT9,SYNDIG1,SLITRK1,NTNG1,PHYHIPL,ATP2B2,PALLD,MYT1L,ERBIN,CAMTA1,CACNA1A,PTBP2,ZFP91,SLC25A27,PRRX1,MAPK10,TOX,CADM2,HP1BP3,STMN4,KCNK2,DLG2,SLC6A15,GPR61" MicroRNA hsa-miR-193b*:mirSVR_highEffct hsa-miR-193b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-13 8.68E-10 4.88E-13 4.47E-12 42 837 "RABEPK,ACER3,MAP6,ATAT1,CLIP1,DSCAML1,SORCS1,FGF1,FHL1,MOG,MAGI3,DGKZ,CACHD1,MSRA,CCDC88A,SLC14A1,B4GALNT1,SEPT3,PCDH11X,CAMK2G,VSTM2A,ATP13A2,TNFRSF1B,SEZ6L,PCSK2,ZMYND8,CASC2,JAM2,SLC22A6,NSD2,NKAIN4,RBPJ,EDRF1,TOMM20,PSMD13,PTAFR,CNIH3,PTPRD,KCNJ10,BSDC1,ELAVL4,YY1AP1" MicroRNA hsa-miR-129-5p:Functional MTI Functional MTI miRTarbase 1.64E-13 8.86E-10 4.97E-13 4.56E-12 36 625 "EPS8,GALNT13,ADD3,SEMA6A,SLC30A10,SOX6,USP28,SESN3,APC,NTNG1,MAGI3,LRRC55,IGSF9B,TMEM151A,CAMTA1,UNC5D,CNDP1,GRM3,ZNF384,HMGB1,COL9A2,RNF14,VCAN,KIAA0408,JAKMIP2,ZC3H11A,NKAIN1,WIPF2,DNAH9,PAK5,L1CAM,ZYG11B,RET,ST8SIA3,PLEKHO1,EPB41L1" MicroRNA hsa-miR-1468:mirSVR_lowEffct hsa-miR-1468:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-13 9.08E-10 5.09E-13 4.67E-12 34 559 "PRR5L,TOMM40L,TESK2,LINC00461,NTNG1,PHYHIPL,SCN3B,KIF1B,CLASP2,BCL2L2,KAZN,CACNA1A,NUDT21,P2RX7,LGI1,NLGN3,DLGAP3,CNTN1,PPP2R5C,FEZ2,MICAL2,KIAA1755,RAB39A,MASP1,CA10,KCNA1,RABGAP1L,KCNK1,KIF2A,GOPC,BSDC1,ZYG11B,TTLL7,GPR61" MicroRNA hsa-miR-543:TargetScan hsa-miR-543 TargetScan 1.68E-13 9.08E-10 5.09E-13 4.67E-12 34 559 "EPS8,ADARB2,AMER2,PKNOX2,CAB39,EMC1,NPAS3,LMO3,GFRA1,GJB1,NUDT21,CAMK2G,NUMA1,GRIK2,MFSD2A,KCNK10,REPS2,PCDH8,DCLK1,CADM1,NEGR1,NMT2,OSBPL3,DOCK7,PROX1,KCNA1,KCNA4,PTPRD,KCND3,ARNT2,LMO1,ELAVL4,EN2,EPB41" MicroRNA hsa-miR-191:mirSVR_highEffct hsa-miR-191:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.98E-13 1.07E-09 6.00E-13 5.50E-12 27 349 "MDM4,DACH2,NPAS3,RGL1,CAMSAP2,GPM6B,CACNA1E,TCF7L2,ZEB1,GRIA4,TJP1,LGI1,TPM3,JAM2,NXPH1,PHACTR3,CNIH3,PTPRD,PARP11,DPP6,C12orf4,RGS7,SEC61A2,SIDT2,FGFBP3,SLC4A10,RPE65" MicroRNA hsa-miR-604:mirSVR_lowEffct hsa-miR-604:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-13 1.14E-09 6.39E-13 5.86E-12 33 531 "PLEKHG5,SLITRK1,DRAXIN,TRIM46,FOLH1,PPFIA1,NTNG1,MIER1,CAPRIN2,RCOR3,ARPP21,KAZN,CAMTA1,NRGN,CAMK2G,GRIA4,GRIK3,MFSD2A,TNFRSF1B,DCLK1,PFKFB3,A2ML1,MFSD4A,PLCH2,DZIP3,ANKS1B,CA10,COPS7A,KCNK2,RAB5B,FAM66C,PIANP,EPB41L2" MicroRNA hsa-miR-563:mirSVR_highEffct hsa-miR-563:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-13 1.15E-09 6.42E-13 5.89E-12 27 350 "ACHE,LGR4,RTN1,LRRC55,SLC8A3,ASCL1,CAPRIN2,ASPH,SORCS3,ASTN1,KIF21B,JPH4,NPAS3,STOX1,VWC2,TLX1,MICAL2,PRKACB,PLPPR5,ITGAV,ZC3H11A,AK5,KCNK2,DBX2,SSPN,ELAVL4,EPB41L1" MicroRNA hsa-miR-34b:PITA hsa-miR-34b:PITA_TOP PITA 2.20E-13 1.19E-09 6.68E-13 6.12E-12 28 379 "WAC,FGF14,ELMOD1,FOXG1,SOX6,MAGI3,SLITRK3,BRINP2,RCOR3,SNAP25,MYT1L,DCAF5,PCDH11X,ADGRL3,PTBP2,OMG,NEURL1,CDC42,C1orf94,PIK3CD,SF1,TOX,PTPRD,PTPRE,KCNMA1,KIF2A,SLC6A15,RCAN2" MicroRNA hsa-miR-942:PITA hsa-miR-942:PITA_TOP PITA 2.21E-13 1.20E-09 6.68E-13 6.13E-12 26 323 "GPR158,LRRTM4,ANK1,AHCYL1,NCAM1,CLASP2,BTRC,WSCD1,TCF7L2,ZEB1,OPCML,TLL2,TNS1,PCDH9,RBFOX2,NRXN1,MAPK10,JAKMIP2,LRP8,PTPRD,KCNMA1,PHC2,RBM12,CBLN2,SLC4A10,EPB41L1" MicroRNA hsa-miR-513b:PITA hsa-miR-513b:PITA_TOP PITA 2.21E-13 1.20E-09 6.68E-13 6.13E-12 26 323 "SORCS1,NLGN4X,APC,DACH2,MYT1L,SOX5,ZCCHC24,AHCYL1,GFRA1,CAMTA1,EML4,GRID1,TMEM257,RBFOX2,FNDC5,NEGR1,PACSIN1,MED1,CRMP1,FAM131B,ITGAV,CADM2,DLG3,GOPC,ZYG11B,RASGRP2" MicroRNA hsa-miR-645:mirSVR_highEffct hsa-miR-645:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-13 1.26E-09 7.01E-13 6.43E-12 29 409 "ACER3,RXRG,FCGR1A,DOCK10,SFMBT2,SCMH1,MTR,PHYHIPL,NEK6,ARHGEF7,PCDH11X,DCLK2,TCF12,PTBP2,TLL2,TMEM257,BEST3,HPSE2,CP,PPP3CB,PUM1,LRRTM3,CADM2,STMN4,KCNK2,DLG2,WIPF2,DNAH9,PARP11" MicroRNA hsa-miR-127-3p:mirSVR_lowEffct hsa-miR-127-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.35E-13 1.27E-09 7.10E-13 6.52E-12 28 380 "LRRTM4,ITSN1,SLITRK3,SHTN1,DACH2,NPAS3,CLASP2,GLS,PCDH11X,CAMTA1,NRGN,PTBP2,GRIA1,GRIA2,P2RX7,MAGI1,ASIC3,CSF3R,RAB39A,USP54,MAPK8,PTPRD,SV2A,NTM,ARNT2,KCNQ2,RAD52,FAM66C" MicroRNA hsa-miR-1299:PITA hsa-miR-1299:PITA_TOP PITA 2.62E-13 1.42E-09 7.92E-13 7.26E-12 29 411 "SYT9,TOMM40L,GPR158,SEMA6A,SOX6,MYT1L,ERBIN,NEUROD1,LUZP2,BTRC,TBX15,ATF7,CACNA1E,GPR88,FBXL16,RBFOX2,NRXN2,PACSIN1,POU3F2,CTNND1,PUM1,LRRTM3,CADM2,CEP170,CSDE1,SRGAP3,SNX27,EPB41L2,RASGRP2" MicroRNA hsa-miR-544:PITA hsa-miR-544:PITA_TOP PITA 2.77E-13 1.50E-09 8.37E-13 7.68E-12 30 442 "ACLY,AMER2,KIAA1109,AMPH,ASTN1,SMARCE1,MYT1L,SALL3,NPAS3,RAP1GAP2,CLASP2,NFIA,PCDH11X,CAMSAP2,CACNA1A,CAMK2G,HNRNPK,CADM1,FAT3,POU3F2,SF1,TENM4,RBPJ,TOX,CSDE1,ABI1,PAK5,RET,RGS7,ABI2" MicroRNA hsa-miR-1308:mirSVR_highEffct hsa-miR-1308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-13 1.57E-09 8.76E-13 8.04E-12 34 570 "EPS8,SYNDIG1,KLRC4,SLITRK1,TMEM156,ELMOD1,C1orf61,SELL,PPFIA1,SHTN1,CCDC88A,ASPH,CACNB2,GRIK2,TGFBR3,CDH10,RBFOX2,LINC01102,PLEKHB1,HNRNPK,TMEFF2,NLGN3,DZIP3,MAPK10,PROX1,LRP8,MAGI2,AK5,ARNT2,DLG3,KLRC2,SLC17A6,FAM13C,ZYG11B" MicroRNA hsa-miR-659:PITA hsa-miR-659:PITA_TOP PITA 3.04E-13 1.64E-09 9.16E-13 8.40E-12 23 249 "SDE2,RTKN,HPCAL4,ANK1,NLGN1,ARHGAP5,PALLD,PCDH11X,UNC5D,TCF12,GPR88,CDC42,CDH8,LGI1,NEGR1,CABP1,RGS6,CTNND1,DNAJC6,JAKMIP2,MAGI2,ABI1,PAK5" MicroRNA "AACTGGA,MIR-145:MSigDB" "AACTGGA,MIR-145:MSigDB" MSigDB 3.13E-13 1.70E-09 9.44E-13 8.66E-12 22 225 "RTKN,SLC25A25,CSMD3,ADD3,SCN3A,SEMA6A,CACHD1,SLC1A2,KIF1B,MYRF,PSD3,ZFYVE9,CABP1,CTNND1,ELMO1,ZC3H11A,SRGAP3,SNX27,PAK5,SLC6A15,RGS7,EFNA3" MicroRNA hsa-miR-345:mirSVR_highEffct hsa-miR-345:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.34E-13 1.81E-09 1.01E-12 9.24E-12 33 540 "EPS8,ADGRV1,MDM4,SLC30A10,MOBP,PPFIA1,SORBS1,ST3GAL3,SLC2A5,DLL3,MLC1,ZNF638,SYT4,ADGRL3,ZEB1,TF,MAEL,HPS5,PDE4B,CADM1,TJP2,CCDC136,CRMP1,USP54,GON4L,PRDM2,OLFM3,PCDH15,KLRC2,C12orf4,RTN4,RAVER2,EPB41L2" MicroRNA hsa-miR-1226:PITA hsa-miR-1226:PITA_TOP PITA 3.38E-13 1.83E-09 1.02E-12 9.33E-12 20 180 "SOX6,PALLD,SOX5,LMO3,ERBIN,SEPT3,HAP1,CAMK2G,CDC42,ACOT7,FAT3,MED1,OSBPL3,SYNC,KCNMA1,DLG2,TMEM255A,ABI1,GPR61,ELAVL3" MicroRNA hsa-miR-1254:mirSVR_highEffct hsa-miR-1254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-13 1.87E-09 1.04E-12 9.55E-12 38 711 "PRR5L,KCNIP2,CLIP1,SORCS1,GRAMD1B,SOX6,PPFIA1,ST3GAL3,ARHGAP5,CAPRIN2,B3GAT1,FYN,SON,ERBIN,ADHFE1,ANO4,FNDC5,BEST3,ANO5,CASC2,CPT1C,FLRT1,MEAF6,BEST1,FAT3,MFSD4A,SF1,PPP3CB,RGS6,USP54,PTAFR,CADM2,SRGAP3,RAD52,DSCAM,PIANP,ABI2,UEVLD" MicroRNA hsa-miR-22-3p:TargetScan hsa-miR-22-3p TargetScan 3.49E-13 1.89E-09 1.05E-12 9.64E-12 30 446 "ACER3,ACLY,PDZD4,NTNG1,ASCL1,MEGF11,CADM3,NPAS3,GFRA1,KIRREL3,CAMK2G,CECR2,BRSK2,AIFM1,KCNK10,PAX6,PADI2,RBFOX2,GPR37L1,CADM1,FTO,RIMS4,MAPK10,PROX1,MAGI2,KCNH1,RAB5B,CAMK1G,PIANP,EPB41L2" MicroRNA "ATGCTGC,MIR-107:MSigDB" "ATGCTGC,MIR-107:MSigDB" MSigDB 3.58E-13 1.94E-09 1.08E-12 9.86E-12 21 203 "SYNDIG1,SLITRK1,ANK1,LRRC55,SLC8A2,PHYHIPL,CAB39,NFIA,BTRC,ADGRL3,SYT6,PSD3,TGFBR3,TPD52,PDE4B,CHRM1,CAMKV,PACSIN1,BSDC1,RET,ST8SIA3" MicroRNA "ATGCTGC,MIR-103:MSigDB" "ATGCTGC,MIR-103:MSigDB" MSigDB 3.58E-13 1.94E-09 1.08E-12 9.86E-12 21 203 "SYNDIG1,SLITRK1,ANK1,LRRC55,SLC8A2,PHYHIPL,CAB39,NFIA,BTRC,ADGRL3,SYT6,PSD3,TGFBR3,TPD52,PDE4B,CHRM1,CAMKV,PACSIN1,BSDC1,RET,ST8SIA3" MicroRNA hsa-miR-520a-5p:PITA hsa-miR-520a-5p:PITA_TOP PITA 3.59E-13 1.95E-09 1.08E-12 9.89E-12 23 251 "RTN1,ASRGL1,SCN3B,CAMK2A,CAMK2G,NUMA1,ZFP91,CDC42,NLGN3,PSD,TOX,CADM2,LRP8,CDH20,SV2A,TMCC2,KCNMA1,SNX27,DLG3,WIPF2,PAK5,BSDC1,RNF220" MicroRNA hsa-miR-525-5p:PITA hsa-miR-525-5p:PITA_TOP PITA 3.59E-13 1.95E-09 1.08E-12 9.89E-12 23 251 "RTN1,ASRGL1,SCN3B,CAMK2A,CAMK2G,NUMA1,ZFP91,CDC42,NLGN3,PSD,TOX,CADM2,LRP8,CDH20,SV2A,TMCC2,KCNMA1,SNX27,DLG3,WIPF2,PAK5,BSDC1,RNF220" MicroRNA hsa-miR-626:PITA hsa-miR-626:PITA_TOP PITA 3.60E-13 1.95E-09 1.08E-12 9.90E-12 18 139 "SEMA6A,PPM1E,SHTN1,SHANK2,ZCCHC24,ZSWIM8,NCDN,HAP1,MAGI1,SF1,TENM4,OSBPL3,CEP170,MAGI2,ZC3H11A,DLG2,KIF2A,RAB5B" MicroRNA hsa-miR-3189:mirSVR_highEffct hsa-miR-3189:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.76E-13 2.04E-09 1.13E-12 1.04E-11 32 510 "ATAT1,CSMD2,GALNT13,GPR158,LRRTM4,PKP4,SESN3,SHTN1,PAAF1,SCG3,NAP1L2,NASP,NELL1,GANAB,GLS,LUZP2,EML4,SYT6,GRIA4,PAH,IGFN1,CASC2,MED1,PROX1,ANKS1B,SPIRE1,PSMD13,PTHLH,LRP8,PTPRD,OLIG1,SSPN" MicroRNA hsa-miR-644:mirSVR_highEffct hsa-miR-644:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.89E-13 2.11E-09 1.17E-12 1.07E-11 34 576 "TMEM74,RTN3,NLGN4X,TOMM40L,FGF1,LRRC7,PKP4,MIER1,URGCP,SLC8A3,TMEM151A,NEK6,NFASC,NCAM1,BCL2L2,GLS,ASTN2,LUZP2,DDHD2,PRUNE2,GPR88,LGI1,PDE1C,TLX1,SLC25A27,BEST1,CNRIP1,MICAL2,PTPRO,DLG2,RTN4,RET,RFX4,EPB41L2" MicroRNA hsa-miR-16-5p:Functional MTI Functional MTI miRTarbase 4.02E-13 2.17E-09 1.20E-12 1.10E-11 59 1557 "ADORA3,SOX6,CCDC80,GPAM,ASPH,EIF4G3,SON,SOX5,AHCYL1,KIF1B,GANAB,FAM168A,ZNF638,DDHD2,BTRC,ATF7,CACNB2,EML4,CAMK2G,CYB561A3,TGFBR3,TPM3,ZNF384,PDE3B,DLGAP3,SERPINE2,CADM1,NRXN1,CAMKV,NEGR1,VAV2,FAT3,ACBD5,PPP2R5C,OSBPL3,RBPJ,PRKAB2,IGSF1,PUM1,ZBTB16,RIMS3,PHYHIP,CSDE1,MED24,ZC3H11A,PTPRD,KCND3,NAV2,KIF2A,TMEM255A,PLEKHB2,RTN4,L1CAM,SEC61A2,SIDT2,ARHGAP12,YY1AP1,EN2,TMEM100" MicroRNA hsa-miR-3184:mirSVR_highEffct hsa-miR-3184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.09E-13 2.21E-09 1.22E-12 1.12E-11 34 577 "TTYH1,ACLY,ARID1A,RTKN,MDM4,ERMN,FOXM1,TRIM46,SELL,ITSN1,MT3,SLC14A1,CGREF1,B4GALNT1,ADAM15,SPART,C11orf87,RGL1,RFFL,USP2,CDC42,PDYN,FADS2,SLC25A27,FEZ1,MAPK10,ECE2,MAGI2,KCNC1,TMCC2,PYGM,ATN1,EFNA3,YY1AP1" MicroRNA hsa-miR-335-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-13 2.30E-09 1.27E-12 1.17E-11 25 305 "ACER3,RTN3,SLC30A10,CADPS,ZCCHC24,GFRA1,AJAP1,NFIA,KLHL4,CACNA1A,CACNA1E,NUCB1,ADAMTS8,PAX6,PCSK2,NEGR1,POU3F2,KCNT2,VCAN,PUM1,STMN4,KCND3,NAV2,KCNN3,BSDC1" MicroRNA hsa-miR-501-3p:mirSVR_highEffct hsa-miR-501-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.39E-13 2.38E-09 1.31E-12 1.20E-11 30 450 "F3,FCGR1A,NTNG1,GPAM,SLITRK3,ST3GAL3,JAKMIP3,ASPH,RCOR3,AHCYL1,ARPP21,NPAS3,PCDH11X,DDHD2,CACNB2,PTBP2,GRIA2,PCDH9,PDE3B,GDAP1L1,CADM1,RNF14,KCNT2,PRKCZ,SIRPA,BDNF-AS,PTHLH,CSDE1,CCDC3,SLC6A15" MicroRNA hsa-miR-215:mirSVR_highEffct hsa-miR-215:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.50E-13 2.44E-09 1.35E-12 1.23E-11 34 579 "MDM4,CSMD3,CDC7,SCN3A,USP28,PKP4,DOCK10,SESN3,CLSTN1,ARHGAP5,SCG3,ATM,KIF21B,NDUFA5,DDHD2,ADGRL3,VXN,LEFTY2,PCDH9,CDH8,CASC2,ZFYVE9,NSD2,PLPPR5,ITGAV,BDNF-AS,HP1BP3,PTPRZ1,KCNK1,PCDH15,DNAH9,RAB5B,PID1,SLC17A6" MicroRNA hsa-miR-192:mirSVR_highEffct hsa-miR-192:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.50E-13 2.44E-09 1.35E-12 1.23E-11 34 579 "MDM4,CSMD3,CDC7,SCN3A,USP28,PKP4,DOCK10,SESN3,CLSTN1,ARHGAP5,SCG3,ATM,KIF21B,NDUFA5,DDHD2,ADGRL3,VXN,LEFTY2,PCDH9,CDH8,CASC2,ZFYVE9,NSD2,PLPPR5,ITGAV,BDNF-AS,HP1BP3,PTPRZ1,KCNK1,PCDH15,DNAH9,RAB5B,PID1,SLC17A6" MicroRNA hsa-miR-181c*:mirSVR_lowEffct hsa-miR-181c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.86E-13 2.63E-09 1.45E-12 1.33E-11 31 483 "SLITRK1,AMPH,ANK2,PDE8B,NAXD,CAPRIN2,ASPH,SMARCE1,GABBR1,ADGRB2,FXYD6,NASP,GNAS,TF,MAEL,CDH8,TPM4,HMGB1,MS4A7,CADM1,SLC25A27,CNRIP1,NRSN1,MASP1,OCIAD1,PTPRE,NKAIN1,PID1,DNM2,SLC17A6,DTNA" MicroRNA hsa-miR-155-5p:Functional MTI Functional MTI miRTarbase 4.90E-13 2.65E-09 1.46E-12 1.34E-11 43 904 "RTN3,ADD3,SOX6,APC,GPAM,SHANK2,ASPH,SMARCE1,PALLD,CAB39,NASP,ERBIN,RGL1,GANAB,GNAS,CAMTA1,WWC1,TMEM136,GPM6B,TCF12,OLR1,INA,TJP1,AIFM1,CD81,PCDH9,TPD52,ZNF384,ACOT7,VAV2,FEZ2,RBPJ,PKN2,WBP1L,TOMM20,KCNN3,CAB39L,PHC2,ZNF248,EEF1A2,RPRD1A,ABI2,EPB41L2" MicroRNA hsa-miR-190a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-13 2.67E-09 1.47E-12 1.35E-11 36 649 "ACER3,GRAMD1B,NLGN4X,KIAA1109,CCDC80,MIER1,LRRC55,MYBPC1,WDTC1,SOX5,AJAP1,NFIA,GRID1,GRIK3,OPCML,CD81,CADM1,NEGR1,SLC25A27,PRRX1,ACBD5,DOCK7,PUM1,PROX1,ZBTB16,PMEPA1,LRP8,PTPRD,KCNK1,KCNN3,RAB5B,L1CAM,SSPN,ABI2,FGFBP3,RCAN2" MicroRNA hsa-miR-6873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.01E-13 2.71E-09 1.49E-12 1.37E-11 28 392 "ACTN2,MDM4,GRAMD1B,TUBB4A,NLGN4X,ASCL1,IGSF9B,ATP1A3,GJB1,SEPT3,GPR26,TMEM151B,DDR2,GRID1,TGFBR3,FBXL16,ZDHHC22,TNS1,CDH8,PTGDR2,GPR37L1,GDAP1L1,RIMS4,CADM2,SMG7,NAV2,ZYG11B,ELAVL3" MicroRNA hsa-miR-3170:mirSVR_highEffct hsa-miR-3170:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.26E-13 2.85E-09 1.57E-12 1.44E-11 42 868 "ACER3,ATAT1,HPCAL4,MOBP,MOG,ITSN1,MAGI3,DGKZ,SHTN1,MSRA,CCDC88A,SLC14A1,DACH2,SORCS3,SON,EMC1,GLS,CAMK2G,GRIA2,GRIK2,CCKBR,AIFM1,SEZ6L,PCSK2,ZMYND8,JAM2,SLC22A6,NSD2,EDRF1,FGFR1OP2,MASP1,PTAFR,CNIH3,COPS7A,PID1,TMEM255A,GNE,FAM13C,BSDC1,RFX4,ARHGAP12,YY1AP1" MicroRNA hsa-miR-588:mirSVR_highEffct hsa-miR-588:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.40E-13 2.92E-09 1.61E-12 1.47E-11 37 686 "RCSD1,LDLRAD3,CSMD2,KLHL32,FCGR1B,FHL1,ANK3,CCDC80,SHTN1,SMARCE1,FYN,SOX5,ARPP21,DCLK2,GPM6A,CLEC9A,TF,P2RX7,TMEM257,DAAM2,MAEL,TNR,PCDH9,ZNF384,PDE3B,PDYN,CASC2,TJP2,PTPA,DOCK7,PKN2,COPS7A,ZC3H11A,PTPRO,PAK5,FAM135B,SEC61A2" MicroRNA hsa-miR-31-5p:TargetScan hsa-miR-31-5p TargetScan 5.48E-13 2.97E-09 1.63E-12 1.50E-11 26 336 "ARID1A,PDZD4,RPH3A,LRRC55,GABBR1,AHCYL1,C11orf87,CLASP2,RHBDL3,CACNB2,CAMK2G,GRIK3,PC,PCDH8,FNDC5,GDAP1L1,FTO,PKN2,CTNND2,RIMS3,DPYSL5,KCNN3,PEX5,RAB5B,FAM135B,RBM12" MicroRNA hsa-miR-1827:mirSVR_highEffct hsa-miR-1827:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.53E-13 2.99E-09 1.64E-12 1.51E-11 46 1024 "ASIC1,SYT9,ADCY2,GALNT13,LRRC7,FGF14,ELMOD1,ANK3,ST3GAL3,TMEM249,CAPRIN2,WDTC1,B3GALT2,TNIK,ADAM15,NDUFA5,GFAP,NELL1,ADHFE1,FAM168A,GLS,ANO4,CACNB2,NUMA1,LINC00839,TIE1,MAGI1,ZMYND8,TMPRSS5,GDAP1L1,SERPINE2,CCDC136,POU3F2,SF1,PPP2R5C,CSF3R,RBPJ,IGSF1,CTNND2,ITGAV,PLPPR1,HP1BP3,SV2A,TMCC2,PEX5,CAMK1G" MicroRNA hsa-miR-593:PITA hsa-miR-593:PITA_TOP PITA 5.77E-13 3.12E-09 1.71E-12 1.57E-11 21 208 "EYA1,DSCAML1,LHFPL4,CPLX2,BCL2L2,ERBIN,NCDN,SEMA4A,CAMTA1,TCF12,GRID1,PTPN5,CELF3,RBFOX2,SEZ6L,SLC25A27,SYNC,OLFM3,SRGAP3,DLG2,DLG3" MicroRNA hsa-miR-99a*:mirSVR_lowEffct hsa-miR-99a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.81E-13 3.14E-09 1.72E-12 1.58E-11 33 551 "LOC100128239,GRAMD1B,GPR158,ITSN1,SORBS1,API5,MSR1,PKNOX2,PDE8B,KIF1B,ZNF638,CAMTA1,VWC2,PTBP2,GRID1,OMG,PDYN,HMGB1,HERC2P3,JAM2,HPR,MEAF6,OSBPL3,PUM1,ZNF385B,CSDE1,KCNJ10,KCNN3,ZNF248,SEC61A2,RPRD1A,RAVER2,C2orf80" MicroRNA hsa-miR-4327:mirSVR_highEffct hsa-miR-4327:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.60E-13 3.58E-09 1.96E-12 1.80E-11 34 587 "ADGRV1,TESK2,AGT,SCN3A,ITSN1,APC,RCOR3,EIF4G3,NCAM1,SYT4,TBX15,VSTM2A,GRIA4,CDC42,LINC01102,NOMO2,PRRX1,CNRIP1,CHD1L,RGS6,MICAL2,PKN2,PUM1,DNAJC6,PTPRD,NKAIN1,PID1,SLC17A6,C12orf4,FAM13C,DTNA,RTN4,EFNA3,SLC4A10" MicroRNA hsa-miR-451:mirSVR_lowEffct hsa-miR-451:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.94E-13 3.76E-09 2.06E-12 1.89E-11 27 368 "CLIP1,SEMA6A,DOCK10,CACHD1,BCAS1,SLCO1A2,DLL3,SALL3,NPAS3,NDUFA5,STOX1,ASTN2,LUZP2,WWC1,TPM3,SERPINE2,PPP2R5C,SDC3,KIAA1755,EDRF1,ANKS1B,KCNA4,KCNK1,KCNMA1,KIF2A,ATN1,RPRD1A" MicroRNA hsa-miR-5006-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-13 3.76E-09 2.06E-12 1.89E-11 23 259 "ADCYAP1R1,TMEM156,ASIC4,BCAN,CACHD1,LRRC55,ZCCHC24,SMOC1,ACSBG1,NFIA,MYRF,TCF7L2,CAMK2G,SYT6,PADI2,SEZ6L,TMEFF2,PHKG1,NEGR1,RGS6,CHD5,ZYG11B,VANGL2" MicroRNA hsa-miR-29c*:mirSVR_lowEffct hsa-miR-29c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.94E-13 3.76E-09 2.06E-12 1.89E-11 22 234 "SORCS1,ITSN1,PPM1E,SHANK2,CGREF1,SEPT3,MLC1,ATF7,PCDH9,OPALIN,SLC25A27,BTF3L4,PPP2R5C,NKAIN4,MASP1,PTAFR,MAGI2,KCNMA1,NKAIN1,FAM135B,PHC2,PIANP" MicroRNA hsa-miR-483-3p:mirSVR_highEffct hsa-miR-483-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.24E-13 3.92E-09 2.15E-12 1.97E-11 35 623 "RCSD1,ADAR,FHL1,SOX6,ANK3,TACC2,ST3GAL3,MSRA,ASPH,RCOR3,JPH4,NELL1,PHLDB1,GANAB,RND1,ZNF638,WWC1,PRUNE2,GPM6B,DDR1,ZEB1,GRIA2,GRID1,FBXL16,PAH,PDE1A,HNRNPK,UBTF,ACBD5,MED1,SNCAIP,NCAN,KCNA4,KCNN3,ABI2" MicroRNA hsa-miR-3122:mirSVR_highEffct hsa-miR-3122:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.26E-13 3.93E-09 2.15E-12 1.97E-11 34 589 "GALNT13,ADD3,NTNG1,MAGI3,ZNF365,RCOR3,ATM,NRG3,JPH4,NEK6,SEPT3,ZNF638,ANO4,ACSL6,TCF12,GRIA4,VWCE,P2RX7,MAEL,PCDH9,TMEFF2,DUSP26,NEGR1,PMP2,USP54,SYNC,PRTFDC1,PTPRE,RABGAP1L,ABI1,GNE,INSYN2,PHC2,SLC4A10" MicroRNA hsa-miR-370:mirSVR_highEffct hsa-miR-370:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.26E-13 3.93E-09 2.15E-12 1.97E-11 34 589 "TTYH1,ATAT1,MDM4,ADD3,NLGN4X,FCGR1A,ASIC4,ANK3,PPM1E,DGKZ,ZCCHC17,SCG3,CAB39,ARPP21,ADGRB2,NCAM1,AJAP1,ARHGEF7,DDHD2,HPS5,MAGI1,LRTM2,HERC2P3,A2ML1,CCDC136,BTF3L4,PRKACB,PSMD13,PRTFDC1,KCNJ11,DBX2,ATL1,ZNF248,UEVLD" MicroRNA hsa-miR-377:PITA hsa-miR-377:PITA_TOP PITA 7.27E-13 3.93E-09 2.15E-12 1.97E-11 30 459 "ARID1A,NLGN1,MADD,SALL3,PCDH11X,SYT4,NKX2-2,CAMTA1,CACNB2,TCF12,EML4,PFKFB3,GDAP1L1,CAMKV,NEGR1,NSD2,DZIP3,PUM1,WBP1L,DNAJC6,ELMO1,KIF2A,SLC6A15,RET,PHC2,VANGL2,LMO1,ABI2,SLC4A10,EPB41" MicroRNA hsa-miR-92a-1*:mirSVR_highEffct hsa-miR-92a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.45E-13 4.04E-09 2.20E-12 2.02E-11 31 491 "ATAT1,TRIM46,USP28,PKNOX2,SPHKAP,NAXD,SMARCE1,PALLD,JPH4,B4GALNT1,DNER,FXYD6,INKA2,LUZP2,DCLK2,ADGRL3,GRIA4,MAEL,MAGI1,HNRNPK,BEST1,RGS6,PRKAB2,KCNJ11,KCNK2,KCNMA1,ATN1,DTNA,RFX4,SLC4A10,EPB41" MicroRNA "ATGAAGG,MIR-205:MSigDB" "ATGAAGG,MIR-205:MSigDB" MSigDB 7.53E-13 4.08E-09 2.22E-12 2.04E-11 18 145 "RTN3,SORBS1,SCMH1,PHYHIPL,JPH4,KIF1B,GANAB,SEPT3,CAMSAP2,GPM6A,MAGI1,PDE3B,ACOT7,MED1,SNX27,DLG2,PHC2,EPB41" MicroRNA hsa-miR-3131:mirSVR_lowEffct hsa-miR-3131:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.86E-13 4.25E-09 2.32E-12 2.13E-11 31 492 "RTN3,ADAR,MOBP,ASRGL1,ST3GAL3,MADD,TAGLN3,LHFPL4,ADAM15,NCAM1,SYT4,KAZN,ANO4,CECR2,GRIA2,TNFRSF1B,LGI1,ACOT7,CPT1C,TJP2,PLXNB3,PPP2R5C,RAB39A,ANKS1B,CSDE1,NTM,TMCC2,SLC17A6,LMO1,OLIG2,RPE65" MicroRNA hsa-miR-1913:mirSVR_highEffct hsa-miR-1913:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.11E-13 4.39E-09 2.39E-12 2.20E-11 30 461 "DUSP27,TOMM40L,CDC42BPA,PI16,CNIH2,APBB1,CACHD1,CGREF1,DNAH17,MTR,SORCS3,GABBR1,GANAB,ARHGEF7,DCLK2,SEMA4A,ADAMTS8,TPM3,ZMYND8,CADM1,CAMKV,SLC25A27,CRMP1,PRDM2,SV2A,DPP6,L1CAM,RPRD1A,BSCL2,SEZ6" MicroRNA hsa-miR-4755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.15E-13 4.41E-09 2.40E-12 2.20E-11 23 261 "ADCYAP1R1,TMEM156,ASIC4,BCAN,CACHD1,LRRC55,ZCCHC24,SMOC1,ACSBG1,NFIA,MYRF,TCF7L2,CAMK2G,SYT6,PADI2,SEZ6L,TMEFF2,PHKG1,NEGR1,RGS6,CHD5,ZYG11B,VANGL2" MicroRNA hsa-miR-621:mirSVR_highEffct hsa-miR-621:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.16E-13 4.42E-09 2.41E-12 2.21E-11 28 400 "MEG3,RTKN,SEMA6A,ELMOD1,TRIM46,SELL,ASRGL1,ANK2,ANK3,PAAF1,MIER1,CAPRIN2,SMARCE1,PHYHIPL,CAB39,DNER,ARHGEF7,GLS,FNDC5,PFKFB3,CAMKV,SLC25A27,CP,RBPJ,DZIP3,HP1BP3,PAK5,VWA5A" MicroRNA hsa-miR-328:PITA hsa-miR-328:PITA_TOP PITA 8.19E-13 4.44E-09 2.41E-12 2.21E-11 17 126 "ASIC1,LGR4,TESK2,LRRTM4,SLITRK3,ST3GAL3,WDTC1,UNC5D,GPM6A,HAP1,PDE4B,CABP1,MED1,FAM131B,KIF2A,WIPF2,EN2" MicroRNA hsa-miR-516a-3p:PITA hsa-miR-516a-3p:PITA_TOP PITA 8.36E-13 4.53E-09 2.46E-12 2.26E-11 21 212 "ASIC1,SLITRK1,SORCS1,SH3GL2,SLITRK3,KIF1B,NCAM1,SYT4,UNC5D,ZEB1,TCF12,EML4,GRIK3,OPCML,TNR,TUB,USP54,KCNN3,WIPF2,DPP6,EN2" MicroRNA hsa-miR-892a:PITA hsa-miR-892a:PITA_TOP PITA 8.82E-13 4.78E-09 2.60E-12 2.38E-11 23 262 "ADCY2,ELMOD1,AMPH,DOCK10,RCOR3,SOX5,CAMTA1,BTRC,ZEB1,RBFOX2,NLGN3,BTF3L4,ACBD5,PNKD,KCNT2,PKN2,SYNC,CEP170,SMG7,TMEM255A,FAM13C,ST8SIA3,RGS7" MicroRNA hsa-miR-1975:mirSVR_highEffct hsa-miR-1975:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.03E-13 4.89E-09 2.65E-12 2.44E-11 33 560 "SDE2,CNTNAP3,LGR4,NDRG2,MOBP,FOXG1,SGIP1,NLGN1,ST3GAL3,BCAS1,CCDC88A,SLC14A1,NCAM1,FAM168A,VAMP1,CACNA1E,ZEB1,PRMT8,CADM1,A2ML1,CCDC136,CNTN1,CP,POU3F2,CTNND1,ZBTB16,WBP1L,DNAJC6,HP1BP3,LRP8,COPS7A,RFX5,ABI2" MicroRNA hsa-miR-219-2-3p:PITA hsa-miR-219-2-3p:PITA_TOP PITA 9.37E-13 5.07E-09 2.75E-12 2.53E-11 20 190 "ABAT,ERMN,SCN3A,KIAA1109,NLGN1,SNAP25,NFIA,PTBP2,CAMK2G,GRIA4,MAGI1,HNRNPK,FAT3,OSBPL3,MAPK8,PMEPA1,OLFM3,GOPC,DSCAM,CBLN2" MicroRNA hsa-miR-130b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.38E-13 5.08E-09 2.76E-12 2.53E-11 26 344 "ACER3,GALNT13,NLGN4X,FGF1,CDC42BPA,ASCL1,IGSF9B,MYBPC1,EMC1,PSD3,TGFBR3,FBXL16,P2RX7,TNS1,GDAP1L1,FAM181B,RGS6,RIMS4,DZIP3,RIMS3,DPYSL5,ZC3H11A,NAV2,ABI2,CBLN2,ELAVL3" MicroRNA hsa-miR-99b*:mirSVR_lowEffct hsa-miR-99b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.62E-13 5.21E-09 2.83E-12 2.59E-11 34 595 "LOC100128239,GRAMD1B,ITSN1,SORBS1,API5,ZNF365,RUFY2,MSR1,PKNOX2,PDE8B,USP33,KIF1B,NFASC,ZNF638,VWC2,GRID1,OMG,PDYN,HMGB1,ASIC3,HERC2P3,JAM2,HPR,MEAF6,OSBPL3,PUM1,ZNF385B,CSDE1,KCNJ10,KCNN3,ZNF248,SEC61A2,RPRD1A,C2orf80" MicroRNA hsa-miR-1250:mirSVR_lowEffct hsa-miR-1250:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.98E-13 5.41E-09 2.93E-12 2.69E-11 32 529 "ACLY,CSMD3,KLHL32,PLA2G6,LRRC55,PKNOX2,SMARCE1,NRG3,PALLD,ARHGEF7,CASTOR3,CAMTA1,ADGRL3,MFSD2A,AIFM1,TNFRSF1B,PCDH8,CDH8,FTO,BTF3L4,RGS6,MICAL2,NCAN,IGSF1,WBP1L,SPIRE1,PTPRO,SLC25A48,DNM2,ATN1,DTNA,SFXN5" MicroRNA hsa-miR-488*:mirSVR_highEffct hsa-miR-488*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-12 5.65E-09 3.06E-12 2.81E-11 39 774 "ABAT,PRR5L,CNTNAP3,WAC,TOMM40L,BCAR3,ANK2,ITSN1,USP16,MIER1,BRINP2,SON,CADM3,CAB39,C11orf87,NDUFA5,GLS,CNDP1,KLHL4,ADAMTS8,CDH10,PDE1C,HPCA,MEAF6,CP,CHD1L,USP54,NRSN1,SYNC,BDNF-AS,PRDM2,KCNA2,C1orf109,KCNK2,SLC25A48,DPP6,DTNA,ZNF248,RCAN2" MicroRNA hsa-miR-610:mirSVR_highEffct hsa-miR-610:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-12 6.28E-09 3.40E-12 3.12E-11 37 704 "MRVI1,KCNIP2,F3,ADD3,FABP7,SLC44A5,FGF14,SOX6,RASA3,APC,CACHD1,ST3GAL3,SMARCE1,RCOR3,PALLD,USP33,NMNAT2,TJP1,TMEM257,CDC42,TPM3,MS4A7,HEPACAM,TJP2,CNTN1,PLD5,PUM1,PTHLH,MAGI2,PTPRD,SMG7,KCNC1,RET,RGR,INSYN2,RNF220,RPRD1A" MicroRNA hsa-miR-1224-5p:mirSVR_highEffct hsa-miR-1224-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-12 6.43E-09 3.48E-12 3.19E-11 36 669 "EMID1,MBP,ACTL6B,USP28,ITSN1,MADD,RUFY2,DACH2,RCOR3,MEGF11,SON,ARHGEF7,NODAL,UNC5D,CNDP1,KLHL4,GPM6B,SYT6,SEZ6L,PDYN,HMGB1,PRRX1,ACBD5,PRKACB,PRKCZ,USP54,MAPK10,FGFR1OP2,KIAA0513,ITGAV,BDNF-AS,BLOC1S6,SV2A,SLC17A6,DBX2,RBM12" MicroRNA hsa-miR-4330:mirSVR_highEffct hsa-miR-4330:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-12 6.52E-09 3.53E-12 3.23E-11 38 741 "LGR4,ACTN2,EYA1,MDM4,CSMD3,NDRG2,CLIP1,ANK2,ITSN1,SH3GL2,SOX1,GART,NEUROD1,GOLGB1,PTBP2,VXN,RFFL,ZNF384,NRXN1,NOMO2,PMP2,CHD1L,FEZ1,PRKACB,PKN2,USP54,SYTL2,CSDE1,KCNA4,PLPPR4,PTPRZ1,KCNK1,PCDH15,RTN4,INSYN2,RBM12,RPRD1A,RCAN2" MicroRNA hsa-miR-516b:PITA hsa-miR-516b:PITA_TOP PITA 1.26E-12 6.80E-09 3.68E-12 3.37E-11 20 193 "SYT9,ADD3,AMPH,BCL2L2,GPR162,ADGRL3,GPM6B,CACNB2,GRIA2,GRIA4,GRM3,PCDH9,DCLK1,RBFOX2,PDYN,NLGN3,CADM1,SRGAP3,ABI2,ARHGAP12" MicroRNA hsa-miR-3186-3p:mirSVR_lowEffct hsa-miR-3186-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-12 7.88E-09 4.26E-12 3.91E-11 19 172 "SYT9,ARID1A,DRAXIN,FHL1,AMPH,ITSN1,APBB1,ST3GAL3,DACH2,ADGRA1,VWCE,ASIC3,CHRNB2,CPT1C,BTF3L4,WBP1L,DLG3,C12orf4,RNF220" MicroRNA hsa-miR-601:mirSVR_highEffct hsa-miR-601:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-12 7.97E-09 4.30E-12 3.95E-11 27 380 "CDHR1,TUBB4A,FGF14,ANK2,PPFIA1,NLGN1,SFMBT2,RCOR3,NRG3,BCL2L2,DDHD2,ADGRL3,GRM3,TPM3,HEPACAM,CAMKV,CCSER2,CNTN1,ACBD5,PRKACB,FMN2,ANKS1B,CSDE1,RAD52,PAK5,INSYN2,ARHGAP12" MicroRNA hsa-miR-377-3p:TargetScan hsa-miR-377-3p TargetScan 1.55E-12 8.42E-09 4.54E-12 4.17E-11 30 473 "ARID1A,MADD,GAD2,NPAS3,NKX2-2,KAZN,CAMTA1,GRIA1,AIFM1,HNRNPK,HEPACAM,GDAP1L1,CADM1,CAMKV,NEGR1,DPYSL5,DNAJC6,HP1BP3,LRP8,RGMA,KCNA6,RABGAP1L,KCNK1,KCNN3,KIF2A,PLEKHB2,JMJD1C,ARHGEF10L,GPR61,EPB41" MicroRNA hsa-miR-671-5p:PITA hsa-miR-671-5p:PITA_TOP PITA 1.56E-12 8.47E-09 4.57E-12 4.19E-11 17 131 "CSMD2,SORCS1,SLC1A2,CAMTA1,TBX15,WSCD1,GPM6A,FNDC5,DLGAP3,ST8SIA5,PACSIN1,PPP2R5C,PTPRD,CALN1,FAM57B,PHC2,EEF1A2" MicroRNA hsa-miR-4283:mirSVR_highEffct hsa-miR-4283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.58E-12 8.57E-09 4.62E-12 4.24E-11 26 352 "TTYH1,ACHE,SYT9,TRIM46,ERICH3,DGKZ,MADD,SNCB,ADAM15,KIF1B,STARD10,FXYD6,NFASC,SEPT3,CASTOR3,GNG3,CECR2,FBXL16,ZNF384,PDE2A,HPCA,SF1,PSD,PTAFR,DLG2,SLC25A18" MicroRNA hsa-miR-1200:mirSVR_highEffct hsa-miR-1200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-12 8.94E-09 4.82E-12 4.42E-11 41 861 "LGR4,TOMM40L,ASIC4,ERICH3,PPM1E,APBA2,NTNG1,BCAS1,PAAF1,SLC14A1,SCG3,MTR,SMARCE1,USP33,ADHFE1,PCDH11X,POPDC3,CAMSAP2,CACNA1E,ZEB1,EML4,VSTM2A,GRIA2,CRB1,INA,P2RX7,TIE1,CDH10,MAGI1,PDE3B,DUSP26,FEZ1,CTNND2,EDRF1,PLPPR5,OCIAD1,KCNMA1,FAM13C,DTNA,ABCC9,SYT15" MicroRNA hsa-miR-6825-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-12 9.01E-09 4.85E-12 4.45E-11 27 382 "EMID1,WAC,ANK1,CLSTN1,PKNOX2,NKX6-2,LHFPL4,RAP1GAP2,NFASC,NDUFA5,FAM168A,NRGN,CAMK2A,JAM2,DLGAP3,UBTF,SPATA6,PACSIN1,CRMP1,PTPA,RGS6,NOS1AP,PHYHIP,BDNF-AS,NAV2,EFNA3,EPB41L1" MicroRNA hsa-miR-1245:mirSVR_highEffct hsa-miR-1245:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-12 9.05E-09 4.87E-12 4.47E-11 34 607 "ACER3,ADGRV1,CSMD3,RTN1,LRRTM4,MOBP,ANK3,ITSN1,SLC2A5,NAP1L2,LMO3,SEPT3,AJAP1,CASTOR3,ANO4,GRIA2,INA,TPM3,CADM1,VCAN,SYNC,PTHLH,PRDM2,CSDE1,RABGAP1L,TMEM255A,GOPC,FAM13C,RET,SYT15,VWA5A,RAVER2,EPB41L2,RCAN2" MicroRNA hsa-miR-218-1*:mirSVR_highEffct hsa-miR-218-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-12 9.12E-09 4.91E-12 4.50E-11 37 713 "RTKN,TMEM156,FGF1,SGIP1,NLGN1,ZNF365,SHANK2,SMARCE1,GABBR1,TTLL9,IDI2-AS1,SPART,CLASP2,ADHFE1,AJAP1,DCLK2,GNAS,ADGRL3,CACNB2,PTBP2,TMEM25,TJP1,CDH8,PIRT,BEST3,PFKFB3,CP,PPP3CB,DOCK7,MAPK10,TOX,LRRTM3,JAKMIP2,LRP8,KCNN3,ZYG11B,UEVLD" MicroRNA hsa-miR-1272:PITA hsa-miR-1272:PITA_TOP PITA 1.72E-12 9.30E-09 5.00E-12 4.59E-11 21 220 "HPCAL4,SLITRK3,SLC8A2,CCDC88A,CLASP2,RHBDL3,POPDC3,CAMSAP2,EML4,MAGI1,NEGR1,NMT2,MED1,DNAJC6,LRP8,STMN4,PTPRD,PEX5,DLG3,RTN4,PAK5" MicroRNA hsa-miR-19b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-12 9.50E-09 5.11E-12 4.69E-11 37 714 "SDE2,CLIP1,WAC,SOX6,SESN3,CCDC80,GPAM,SYBU,MIER1,CAPRIN2,ATM,PALLD,SON,CAB39,SPART,SMOC1,RGL1,NFIA,VAMP1,CAMTA1,CAMSAP2,PRUNE2,PTBP2,DAAM2,TNFRSF1B,ZFYVE9,CCSER2,BTF3L4,FAT3,ACBD5,PRKACB,WBP1L,LRP8,CEP170,RAB5B,ATG16L1,ARHGAP12" MicroRNA hsa-miR-1204:mirSVR_lowEffct hsa-miR-1204:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-12 9.54E-09 5.12E-12 4.70E-11 33 574 "MAP6,IL17D,CDC42BPA,ANK2,ITSN1,APBA2,MAGI3,SLC14A1,ASCL1,TNIK,SALL3,TTLL9,ALDH1L1,SEPT3,ARHGEF7,GNAS,WSCD1,MAGI1,DUSP26,GDAP1L1,SEMA5B,NMT2,FADS2,CCDC136,NECAB2,PLCH2,GON4L,KCNC1,DPP6,ATN1,GNE,SFXN5,EPB41" MicroRNA hsa-miR-324-3p:PITA hsa-miR-324-3p:PITA_TOP PITA 1.99E-12 1.08E-08 5.77E-12 5.30E-11 19 175 "CSMD2,SORCS1,SEMA6C,CNIH2,SORCS3,WDTC1,GANAB,RND1,AJAP1,CAMTA1,CADM1,SLC25A27,RIMS4,FAM131B,RAB5B,PHC2,EFNA3,ELAVL3,RASGRP2" MicroRNA hsa-miR-665:TargetScan hsa-miR-665 TargetScan 2.05E-12 1.11E-08 5.94E-12 5.45E-11 26 356 "ADCYAP1R1,DRAXIN,KIAA1614,PKNOX2,NSG2,KIF21B,JPH4,B4GALNT1,AJAP1,SEMA4A,NODAL,NRGN,HAP1,GRIK3,OPCML,IGFN1,FNDC5,HMGB1,DLGAP3,GDAP1L1,COL9A2,RIMS4,ECE2,KCNN3,PHC2,BSCL2" MicroRNA hsa-miR-892b:PITA hsa-miR-892b:PITA_TOP PITA 2.05E-12 1.11E-08 5.94E-12 5.45E-11 21 222 "SYT9,UNC79,NTNG1,ASCL1,PALLD,B4GALNT1,CLASP2,CACNA1E,CAMK2G,OMG,FBXL16,TJP1,RBFOX2,ARHGAP19,TUB,MED1,KIAA1755,WBP1L,CA10,CADM2,ELAVL4" MicroRNA hsa-miR-339-3p:mirSVR_lowEffct hsa-miR-339-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.12E-12 1.15E-08 6.15E-12 5.65E-11 27 386 "PAAF1,SLC6A9,ARFGAP2,SLC14A1,ARFGAP1,WDTC1,SALL3,ADAM15,NCAM1,ZNF638,PTBP2,TMEM151B,NUMA1,DAAM2,PFKFB3,ARHGAP22,SULT4A1,MFSD4A,SNCAIP,PRKCZ,CTNND2,WBP1L,TOMM20,KCNMA1,FAM66C,RPRD1A,SLC4A10" MicroRNA hsa-miR-219-5p:mirSVR_highEffct hsa-miR-219-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.14E-12 1.16E-08 6.19E-12 5.68E-11 30 479 "EYA1,LINC00461,HPCAL4,PPFIA1,NTNG1,ST3GAL3,ZNF365,SCG3,SORCS3,SOX5,ILDR2,GAD2,SYT4,GNAS,ADGRL3,ACSL6,CACNA1E,GRIK2,TGFBR3,INA,LGI1,BEST1,CNRIP1,CP,RAB39A,DNAJC6,PCDH15,C12orf4,SSPN,SLC4A10" MicroRNA hsa-miR-101:PITA hsa-miR-101:PITA_TOP PITA 2.14E-12 1.16E-08 6.19E-12 5.68E-11 30 479 "ASIC1,ACLY,EYA1,ARID1A,UNC79,AMPH,CCDC88A,ATP2B2,ERBIN,NEUROD1,SYT4,CAMTA1,CACNB2,TMEM257,PCDH8,MAGI1,CADM1,NEGR1,SULT4A1,FAT3,POU3F2,CTNND2,KIAA0408,PTCH1,MAGI2,KCNA1,KCNA6,RABGAP1L,SLC17A6,EPB41L1" MicroRNA hsa-miR-127-5p:PITA hsa-miR-127-5p:PITA_TOP PITA 2.23E-12 1.21E-08 6.46E-12 5.93E-11 22 248 "ACLY,SLITRK1,SGIP1,DOCK10,RCOR3,CADM3,LHFPL4,NCAM1,RGL1,NEUROD1,RND1,CAMSAP2,CAMK2G,CAMKV,NXPH1,PTCH1,CADM2,OCIAD1,JMJD1C,RGS7,EFNA3,GPR61" MicroRNA hsa-miR-455-3p.2:TargetScan hsa-miR-455-3p.2 TargetScan 2.23E-12 1.21E-08 6.46E-12 5.93E-11 22 248 "CSMD3,ADCY2,DRAXIN,ANK3,CCDC88A,B3GAT1,EIF4G3,MYT1L,CPLX2,NFASC,LMO3,NFIA,GRIA1,GRID1,OPCML,GUCY1A2,CHGA,POU3F2,PPP3CB,LRP8,ABI2,RCAN2" MicroRNA hsa-miR-626:mirSVR_highEffct hsa-miR-626:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-12 1.21E-08 6.49E-12 5.95E-11 37 720 "EYA1,ATAT1,FGF14,SYBU,SHTN1,SLC14A1,ASPH,ATM,TNIK,ZCCHC24,GAD2,IDI2-AS1,ERBIN,PTBP2,AKNA,PCDH9,MAGI1,TMEFF2,BEST1,CNRIP1,VCAN,PLPP4,USP54,MAPK8,CEP170,MAGI2,ZC3H11A,AK5,KCNJ9,PCDH15,KIF2A,RAB5B,PARP11,SLC25A18,DSCAM,DTNA,ABCC9" MicroRNA hsa-miR-140-3p:PITA hsa-miR-140-3p:PITA_TOP PITA 2.28E-12 1.23E-08 6.58E-12 6.04E-11 25 329 "GPR158,SCN3A,LRRC7,FOXG1,SGIP1,PPM1E,GPAM,SNAP25,DNER,FXYD6,NCDN,PCDH11X,TLL2,PCDH8,RBFOX2,PACSIN1,NCAN,WBP1L,SYNC,SIRPA,PTCH1,SRGAP3,KCNMA1,GOPC,VANGL2" MicroRNA hsa-miR-1269:mirSVR_highEffct hsa-miR-1269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.30E-12 1.25E-08 6.66E-12 6.11E-11 32 546 "ACLY,SYNDIG1,WLS,SLITRK1,SORCS1,PPFIA1,MAGI3,MSR1,MSRA,SNAP25,TNIK,CAB39,NEUROD1,TBX15,TCF12,PCDHGA3,GRIK2,LINC00839,TMEM257,LGI1,TPM4,PDE1A,NRXN1,C11orf49,VCAN,ECE2,ELMO1,PRDM2,LRP8,NTM,DLG2,SLC4A10" MicroRNA hsa-miR-4256:mirSVR_highEffct hsa-miR-4256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-12 1.31E-08 6.98E-12 6.41E-11 32 547 "SDE2,CDC7,GRAMD1B,TESK2,MOG,SOX6,ST3GAL3,CLSTN1,ALDH4A1,ATP1A2,KIF21B,NDUFA5,DCAF5,GLS,PCDH11X,GPM6A,PTBP2,SYT6,P2RX7,TLL2,HPSE2,POU3F2,MASP1,ZNF385B,ZC3H11A,OLFM3,PTPRO,PCDH15,NAV2,PID1,SUSD4,ABI1" MicroRNA hsa-miR-371-3p:mirSVR_lowEffct hsa-miR-371-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-12 1.34E-08 7.14E-12 6.55E-11 29 450 "EYA1,MRVI1,KLHL32,WAC,FCGR1A,CAPRIN2,ATM,MEGF11,USP33,TNIK,ARPP21,ADGRB2,CLASP2,GLS,ROBO3,PTBP2,PCDH9,MAGI1,CASC2,HERC2P3,CAMKV,C11orf49,RGS6,FEZ2,IGSF1,TOMM20,PRDM2,CEP170,OCIAD1" MicroRNA hsa-miR-1292:mirSVR_lowEffct hsa-miR-1292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-12 1.48E-08 7.91E-12 7.25E-11 34 618 "RTN3,RCSD1,CHST15,TESK2,FGF14,SEMA6C,ANXA7,SORBS1,STK32C,NSG2,ASCL1,ARFGAP1,SOX1,NEK6,ADGRB2,NCAM1,C11orf87,PHLDB1,NRGN,AZIN2,SHISA7,CCKBR,NEURL1,ZDHHC22,PADI2,TMEFF2,CADM1,CPT1C,MICAL1,MFSD4A,RAB39A,KCNA6,PLEKHB2,RNF220" MicroRNA hsa-miR-1208:PITA hsa-miR-1208:PITA_TOP PITA 2.78E-12 1.50E-08 8.01E-12 7.35E-11 24 304 "LGR4,LDLRAD3,CSMD3,ADAR,ADD3,SLC1A2,MIER1,SLC8A3,CCDC88A,ASTN1,SNAP25,MYT1L,AHCYL1,JPH4,CAMTA1,CAMSAP2,BTF3L4,FAT3,PTCH1,CADM2,KCNK2,RBM12,RAVER2,EPB41L1" MicroRNA hsa-miR-192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.88E-12 1.56E-08 8.31E-12 7.62E-11 44 994 "EPS8,RIMKLA,CNTNAP3,MDM4,CDC7,ASRGL1,PKP4,APC,CLSTN1,SCMH1,ASPH,EMC1,LHFPL4,PSRC1,TMEM136,GPR19,PTBP2,VXN,GRIA1,ARHGAP19,TPM4,PDE2A,CADM1,ANLN,TJP2,BTF3L4,NSD2,FAAP20,PNKD,ATRNL1,USP54,EDRF1,ZNF385B,ITGAV,LRP8,COPS7A,BLOC1S6,PTPRE,CAB39L,RAP1GAP,RET,PHC2,ZNF248,EEF1A2" MicroRNA hsa-miR-199a-5p:TargetScan hsa-miR-199a-5p TargetScan 2.95E-12 1.60E-08 8.49E-12 7.79E-11 28 422 "ACHE,CLIP1,ADD3,KIAA1109,ASRGL1,ANK3,NTNG1,ATP1A2,ATP2B2,GANAB,MYRF,BTRC,DDR1,CACNB2,CECR2,RFFL,GRIK3,ATP13A2,P2RX7,CDH8,ARHGAP19,PKN2,MAPK8,RGMA,KCND3,RGS10,ARHGAP12,EPB41L1" MicroRNA hsa-miR-199b-5p:TargetScan hsa-miR-199b-5p TargetScan 2.95E-12 1.60E-08 8.49E-12 7.79E-11 28 422 "ACHE,CLIP1,ADD3,KIAA1109,ASRGL1,ANK3,NTNG1,ATP1A2,ATP2B2,GANAB,MYRF,BTRC,DDR1,CACNB2,CECR2,RFFL,GRIK3,ATP13A2,P2RX7,CDH8,ARHGAP19,PKN2,MAPK8,RGMA,KCND3,RGS10,ARHGAP12,EPB41L1" MicroRNA hsa-miR-323a-3p:TargetScan hsa-miR-323a-3p TargetScan 2.98E-12 1.62E-08 8.59E-12 7.88E-11 26 362 "GRAMD1B,MYT1L,SALL3,NEK6,RAP1GAP2,NASP,LMO3,NFIA,MFSD2A,PCDH8,PDE4B,HNRNPK,CRLS1,NCAN,PLD5,PUM1,LRRTM3,DNAJC6,JAKMIP2,HP1BP3,KCND3,ARNT2,RAB5B,GNE,EFNA3,ABI2" MicroRNA hsa-miR-186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-12 1.66E-08 8.83E-12 8.10E-11 29 454 "ECSIT,FOXRED2,DRAXIN,FGF1,SLC8A3,ATM,BCL2L2,WWC1,CACNA1A,CACNB2,VXN,OLR1,MFSD2A,P2RX7,PAH,KCNK10,HMGB1,OPALIN,COL9A2,ATCAY,NCAN,ZBTB16,PTAFR,OCIAD1,KCND3,RABGAP1L,GNE,VANGL2,SFXN5" MicroRNA hsa-miR-450b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-12 1.75E-08 9.27E-12 8.50E-11 20 203 "ACER3,ARID1A,WAC,SEMA6A,SLC30A10,SESN3,GAS7,MIER1,SLC7A14,LRRC55,SALL3,UNC5D,HMGB1,UBTF,COL9A2,VCAN,RBPJ,MAPK8,KIAA0408,ST8SIA3" MicroRNA hsa-miR-326:mirSVR_highEffct hsa-miR-326:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.27E-12 1.77E-08 9.38E-12 8.61E-11 36 693 "SYT9,KCNIP2,ADARB2,TOMM40L,FGF1,CDC42BPA,ITSN1,MAGI3,CACHD1,PAAF1,ARFGAP2,TMEM108,ZSWIM8,ARPP21,NPAS3,ERBIN,ZNF638,PSRC1,CRB1,CDH8,TPM3,PRMT8,PLXNB3,CHD1L,PPP3CB,MICAL2,OSBPL3,NCAN,C1orf109,NAV2,DLG3,NKAIN1,SLC25A48,DBX2,BSDC1,ZNF248" MicroRNA hsa-miR-532-3p:mirSVR_highEffct hsa-miR-532-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.27E-12 1.77E-08 9.39E-12 8.62E-11 34 622 "ARID1A,WAC,ERMN,DRAXIN,ST3GAL3,CAPRIN2,ATP1A2,EIF4G3,DKK3,ENKUR,GART,ACSBG1,DDHD2,CAMK2G,GRIA4,CRB1,PRMT8,FNDC5,NLGN3,CHD1L,MICAL2,PRKACB,MAPK8,PSD,SPIRE1,STMN4,KCNK2,FAM66C,GOPC,CRTAC1,PHC2,ABI2,SLC4A10,C2orf80" MicroRNA hsa-miR-410:PITA hsa-miR-410:PITA_TOP PITA 3.38E-12 1.83E-08 9.70E-12 8.90E-11 26 364 "EPS8,BCAR3,ELMOD1,AQP4,ARHGAP5,DACH2,PHYHIPL,ATP2B2,NDUFA5,GFRA1,RND1,CAMSAP2,WWC1,TCF12,PTBP2,NUDT21,GRIA2,PCDH8,RBFOX2,HMGB1,TMEFF2,VAV2,PTCH1,CSDE1,SNX27,RTN4" MicroRNA hsa-miR-220c:PITA hsa-miR-220c:PITA_TOP PITA 3.53E-12 1.91E-08 1.01E-11 9.29E-11 20 204 "ARID1A,SLITRK1,LRRC7,PPM1E,SNAP25,SOX5,CPLX2,GJB1,CACNA1A,CAMK2G,PCSK2,CHD5,PUM1,PHYHIP,PTCH1,PMEPA1,HP1BP3,PEX5,PLEKHB2,ARHGAP12" MicroRNA hsa-miR-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.53E-12 1.91E-08 1.01E-11 9.29E-11 42 921 "RABEPK,ARID1A,WLS,ADAR,ERMN,SCN3A,MOBP,SOX6,ERICH3,ANK1,PI16,API5,SHTN1,MIER1,ASPH,USP33,SOX5,RCOR2,ZNF638,PTBP2,NUDT21,EML4,CAMK2G,CDC42,TPM3,TPM4,ZNF384,UBTF,RIMS4,EDRF1,SYTL2,TUBB2B,HP1BP3,ZC3H11A,PTPRD,RABGAP1L,KIF2A,PLEKHB2,L1CAM,ABI2,BSCL2,EPB41L2" MicroRNA hsa-miR-1202:PITA hsa-miR-1202:PITA_TOP PITA 3.70E-12 2.00E-08 1.06E-11 9.72E-11 18 159 "SLITRK1,SNX30,PDZD4,NTNG1,SLC1A2,RGL1,RND1,GLS,DCLK2,EML4,TPM3,MEAF6,BTF3L4,ARHGEF4,TOX,RIMS3,PTCH1,PHC2" MicroRNA hsa-miR-376a:PITA hsa-miR-376a:PITA_TOP PITA 3.86E-12 2.09E-08 1.11E-11 1.02E-10 20 205 "DSCAML1,NLGN4X,PPM1E,ARHGAP5,DCAF5,SYT4,GRIK2,TJP1,PDE4B,MED1,FAM131B,COPS7A,SRGAP3,ARNT2,SLC17A6,PAK5,SLC6A15,SIDT2,SLC4A10,EN2" MicroRNA hsa-miR-376b:PITA hsa-miR-376b:PITA_TOP PITA 3.86E-12 2.09E-08 1.11E-11 1.02E-10 20 205 "DSCAML1,NLGN4X,PPM1E,ARHGAP5,DCAF5,SYT4,GRIK2,TJP1,PDE4B,MED1,FAM131B,COPS7A,SRGAP3,ARNT2,SLC17A6,PAK5,SLC6A15,SIDT2,SLC4A10,EN2" MicroRNA hsa-miR-455-3p:PITA hsa-miR-455-3p:PITA_TOP PITA 4.20E-12 2.28E-08 1.20E-11 1.10E-10 22 256 "RTN3,NLGN4X,SEMA6A,SLC1A2,ARFGAP2,B3GAT1,DKK3,ACSL6,PCDH9,MAGI1,PRMT8,FNDC5,NRXN1,PNKD,TENM4,PRKAB2,KCNA1,KCNJ4,SNX27,SLC17A6,C12orf4,RBM12" MicroRNA hsa-miR-498:PITA hsa-miR-498:PITA_TOP PITA 4.20E-12 2.28E-08 1.20E-11 1.10E-10 22 256 "EYA1,ADAR,FGF1,ITSN1,NLGN1,PKNOX2,NCDN,CACNA1A,EML4,CAMK2G,GRIA2,TMEM257,KCNK10,PDE4B,CCSER2,PRRX1,PPP2R5C,PTCH1,CADM2,DLG2,DLG3,ATL1" MicroRNA hsa-miR-489-3p:TargetScan hsa-miR-489-3p TargetScan 4.40E-12 2.38E-08 1.26E-11 1.15E-10 21 231 "EYA1,MRVI1,KLHL32,ADCYAP1R1,CDC7,PKP4,MAGI3,GRIA4,GRIK2,OPCML,GUCY1A2,PAX6,CDH8,HPSE2,MAPK8,PROX1,DNAJC6,JAKMIP2,CADM2,KCND3,ELAVL4" MicroRNA hsa-miR-24-1*:mirSVR_highEffct hsa-miR-24-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-12 2.47E-08 1.31E-11 1.20E-10 27 399 "SYT9,LGR4,KLHL32,CDC7,DRAXIN,HOGA1,MOBP,SGIP1,ASPH,ARPP21,ERBIN,GLS,TCF7L2,TCF12,CECR2,GRIA4,OLR1,PCDH9,CADM1,NSD2,NXPH1,PPP2R5C,IGSF1,NRSN1,TOMM20,KCNK2,SLC6A15" MicroRNA hsa-miR-1263:mirSVR_highEffct hsa-miR-1263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.59E-12 2.49E-08 1.31E-11 1.20E-10 26 369 "ACER3,DUSP27,CLIP1,KLHL32,PPM1E,API5,CADPS,PHYHIPL,C11orf87,PHLDB1,NEUROD1,TMEM136,GRIA2,CDH8,TPM3,ZMYND8,A2ML1,ACBD5,ANKS1B,BDNF-AS,C1orf109,KCNK1,CAB39L,FAM13C,EFNA3,ELAVL4" MicroRNA "ATGTTAA,MIR-302C:MSigDB" "ATGTTAA,MIR-302C:MSigDB" MSigDB 4.78E-12 2.59E-08 1.36E-11 1.25E-10 21 232 "CSMD3,ADD3,LRRTM4,FOXG1,USP33,SON,WDTC1,ZCCHC24,SALL3,UNC5D,ADGRL3,PCDH9,TPD52,MAGI1,POU3F2,FMN2,CTNND2,PLPPR5,PTPRE,PAK5,CBLN2" MicroRNA hsa-miR-3117:mirSVR_highEffct hsa-miR-3117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.05E-12 2.74E-08 1.44E-11 1.32E-10 34 632 "LRRTM4,PPFIA1,DOCK10,NTNG1,SORBS1,SHTN1,BCO1,RCOR3,COLGALT2,PCDH11X,ZNF638,LUZP2,DDHD2,GRID1,ZFP91,MAEL,PDE1C,ZMYND8,BEST3,ASIC3,HEPACAM,NEGR1,MFSD4A,RNF14,ATRNL1,VCAN,NRSN1,HP1BP3,SLC17A6,RASGRF1,PAK5,SLC6A15,RFX5,VWA5A" MicroRNA hsa-miR-1538:mirSVR_lowEffct hsa-miR-1538:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.22E-12 2.83E-08 1.49E-11 1.37E-10 29 464 "DISP3,PI16,JAKMIP3,SCMH1,ATP2B2,STARD10,GLS,OS9,GNAS,DDR1,CECR2,NUCB1,BRSK2,SPX,AIFM1,TNFRSF1B,PLXNB3,MFSD4A,SF1,PPP2R5C,PHYHIP,PSMD13,ELMO1,OCIAD1,DNM2,RAP1GAP,ATN1,ZYG11B,LMO1" MicroRNA hsa-miR-637:mirSVR_highEffct hsa-miR-637:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-12 2.86E-08 1.51E-11 1.38E-10 33 598 "PRR5L,ATAT1,ARID1A,NDRG2,KLHL32,DSCAML1,FGF14,SELL,ANXA7,PKP4,TTLL9,INKA2,GANAB,SEPT3,CASTOR3,SYT4,CAMTA1,ANO4,PCDHGA3,BRSK2,GRM3,LGI1,NLGN3,NRXN2,CRLS1,FEZ1,NRSN1,AK5,KCNJ9,PCDH15,PEX5,RFX4,EFNA3" MicroRNA hsa-miR-1193:TargetScan hsa-miR-1193 TargetScan 5.63E-12 3.05E-08 1.60E-11 1.47E-10 21 234 "ACER3,ATP1A2,KIF21B,AJAP1,NHLH1,KLHL4,DIRAS1,GPR26,FBXL16,DAAM2,REPS2,PDE3B,KIAA1549L,NEGR1,PRKACB,DNAJC6,CEP170,RAB5B,GNE,ABI2,PLEKHO1" MicroRNA "GCATTTG,MIR-105:MSigDB" "GCATTTG,MIR-105:MSigDB" MSigDB 5.65E-12 3.06E-08 1.61E-11 1.48E-10 18 163 "LDLRAD3,SOX6,SON,ARHGEF7,CAMK2G,GRID1,TJP1,ZDHHC22,TPM3,HNRNPK,NRXN1,KIAA0408,CA10,PRDM2,CCDC3,RAD52,ST8SIA3,SSPN" MicroRNA hsa-miR-513a-5p:PITA hsa-miR-513a-5p:PITA_TOP PITA 5.71E-12 3.09E-08 1.63E-11 1.49E-10 22 260 "EPS8,EYA1,ADD3,SORCS1,LRRC7,ERICH3,PPM1E,SLC1A2,NPAS3,UNC5D,PSRC1,CACNA1A,PCSK2,POU3F2,CTNND1,WBP1L,MAGI2,SMG7,SRGAP3,PEX5,JMJD1C,CBLN2" MicroRNA hsa-miR-760:PITA hsa-miR-760:PITA_TOP PITA 6.03E-12 3.27E-08 1.72E-11 1.57E-10 20 210 "FGF1,ANK1,CCDC88A,SMARCE1,SNCB,BCL2L2,RND1,CAMK2G,GRIN1,MFSD2A,TMEM257,TPM3,TJP2,RIMS4,PRKAB2,PUM1,KIAA0513,DPYSL5,KCNMA1,DLG3" MicroRNA hsa-miR-221*:mirSVR_highEffct hsa-miR-221*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.07E-12 3.29E-08 1.73E-11 1.58E-10 35 672 "EMID1,SORCS1,TOMM40L,HOGA1,LINC00461,LRRC7,TRIM46,ITSN1,BCO1,DACH2,ASPH,TTLL9,IDI2-AS1,SPART,NCAM1,ALDH1L1,CACNA1E,PTBP2,TMEM151B,GRIK2,TMEM25,PRMT8,HMGB1,HERC2P3,PPP2R5C,SNCAIP,NCAN,MAPK10,ANKS1B,COPS7A,MAGI2,ARNT2,KCNK2,SLC6A15,RFX4" MicroRNA hsa-miR-26a-5p:TargetScan hsa-miR-26a-5p TargetScan 6.28E-12 3.40E-08 1.78E-11 1.64E-10 37 746 "PRR5L,ACER3,RIMKLA,RCSD1,RTN1,ANK2,APC,NLGN1,ATP1A2,KIF21B,GAD2,LHFPL4,NEK6,CLASP2,KAZN,CAMSAP2,CAMK2A,DDR2,PSD3,DCLK1,PDE3B,PDE4B,PFKFB3,KIAA1549L,CCSER2,ACBD5,PPP3CB,CHD5,CTNND2,ANKS1B,JAKMIP2,CDH20,PTPRD,KCNK1,KCNN3,ABI2,ELAVL3" MicroRNA hsa-miR-26b-5p:TargetScan hsa-miR-26b-5p TargetScan 6.28E-12 3.40E-08 1.78E-11 1.64E-10 37 746 "PRR5L,ACER3,RIMKLA,RCSD1,RTN1,ANK2,APC,NLGN1,ATP1A2,KIF21B,GAD2,LHFPL4,NEK6,CLASP2,KAZN,CAMSAP2,CAMK2A,DDR2,PSD3,DCLK1,PDE3B,PDE4B,PFKFB3,KIAA1549L,CCSER2,ACBD5,PPP3CB,CHD5,CTNND2,ANKS1B,JAKMIP2,CDH20,PTPRD,KCNK1,KCNN3,ABI2,ELAVL3" MicroRNA hsa-miR-625*:mirSVR_highEffct hsa-miR-625*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.31E-12 3.42E-08 1.79E-11 1.64E-10 33 602 "SDE2,LGR4,SLC44A5,GPR158,LRRC7,PKP4,API5,SLC2A5,ASPH,ATM,SON,DNER,C11orf87,CLASP2,NEUROD1,SLCO1C1,GRIA4,RFFL,LGI1,TMEFF2,CADM1,PPP3CB,PLPPR5,CADM2,HP1BP3,PTPRD,PLPPR4,DLG2,RALGDS,RAVER2,RPE65,TMEM100,BAALC" MicroRNA hsa-miR-7106-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.42E-12 3.48E-08 1.82E-11 1.67E-10 38 784 "DPF1,MAG,EMID1,ADAR,ANK1,CLSTN1,SLC1A2,RPH3A,DNAH17,KBTBD12,ZCCHC24,TTLL9,RAP1GAP2,GNG3,GNG4,TPM3,BEST3,SCRG1,PFKFB3,BTF3L4,SPATA6,PACSIN1,FAT3,MFSD4A,CRMP1,RGS6,DOCK7,DPYSL5,TOMM20,NAV2,SNX27,DNAH9,PLEKHB2,PARP11,PHC2,EFNA3,ABI2,EPB41L1" MicroRNA hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 6.42E-12 3.48E-08 1.82E-11 1.67E-10 25 345 "EPS8,MRVI1,ADCYAP1R1,ADD3,FGF1,PPM1E,CACHD1,KIAA1614,AHCYL1,CLASP2,ALDH1L1,PHLDB1,FAM168A,CACNA1A,PSD3,KCNK10,PC,PDE3B,FNDC5,SDC3,CTNND1,RIMS3,JAKMIP2,KCNC1,DLG3" MicroRNA hsa-miR-193a-3p:PITA hsa-miR-193a-3p:PITA_TOP PITA 6.61E-12 3.58E-08 1.87E-11 1.72E-10 17 143 "FGF1,CLSTN1,YPEL4,BCL2L2,ERBIN,CAMTA1,PCSK2,CADM1,KIAA1549L,CAMKV,CCSER2,PPP2R5C,CTNND2,FAM131B,ZC3H11A,RBM12,EN2" MicroRNA hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA_TOP PITA 6.96E-12 3.77E-08 1.97E-11 1.81E-10 18 165 "LRRTM4,KIAA1109,SHTN1,ERBIN,NEUROD1,PCDH11X,ATF7,ZFP91,PCDH9,HMGB1,MED1,TOX,TUBB2B,DLG3,ABI1,GOPC,PAK5,RET" MicroRNA "TTTTGAG,MIR-373:MSigDB" "TTTTGAG,MIR-373:MSigDB" MSigDB 7.18E-12 3.89E-08 2.03E-11 1.87E-10 20 212 "MBP,KCNIP2,DSCAML1,WAC,PKP4,PPM1E,PKNOX2,ARHGAP5,ZCCHC24,NMNAT2,SYT4,GRM3,PTPN5,IFFO1,PPP2R5C,PMEPA1,CSDE1,GOPC,SH3GLB1,EN2" MicroRNA hsa-miR-193b:PITA hsa-miR-193b:PITA_TOP PITA 7.40E-12 4.01E-08 2.09E-11 1.92E-10 17 144 "FGF1,CLSTN1,YPEL4,BCL2L2,ERBIN,CAMTA1,PCSK2,CADM1,KIAA1549L,CAMKV,CCSER2,PPP2R5C,CTNND2,FAM131B,ZC3H11A,RBM12,EN2" MicroRNA hsa-miR-1537:mirSVR_lowEffct hsa-miR-1537:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.44E-12 4.03E-08 2.11E-11 1.93E-10 31 537 "MBP,PNMA8B,KIAA1109,ELMOD1,MOBP,LRRC4C,MIER1,ATP2B2,SON,ZCCHC24,NMNAT2,KIF1B,NPAS3,ARHGEF7,ASTN2,LUZP2,WWC1,ATF7,IGSF21,PCDH8,HMGB1,TUB,POU3F2,PPP2R5C,KIAA0408,LRRTM3,PRDM2,CSDE1,PTPRE,TMCC2,ABCC9" MicroRNA hsa-miR-217:PITA hsa-miR-217:PITA_TOP PITA 7.69E-12 4.17E-08 2.17E-11 2.00E-10 24 319 "CSMD3,RTN1,SEMA6A,ELMOD1,SFPQ,ANK3,PPM1E,SLITRK3,TACC2,SLC1A2,DACH2,NAP1L2,NEUROD1,NFIA,GLS,ADGRL3,GPM6A,ZEB1,GRIK2,ANLN,DOCK7,KIAA0408,LRRTM3,ARHGAP12" MicroRNA hsa-miR-191*:mirSVR_highEffct hsa-miR-191*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.78E-12 4.21E-08 2.20E-11 2.02E-10 21 238 "MEG3,WAC,SEMA6C,SGIP1,RCOR3,ARHGEF7,DDHD2,CAMTA1,NPPA,ZEB1,GPR17,ZFP91,PDYN,HMGB1,CHD1L,DZIP3,MAPK8,PSMD13,OCIAD1,RABGAP1L,ZNF248" MicroRNA hsa-miR-1202:mirSVR_highEffct hsa-miR-1202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.80E-12 4.23E-08 2.20E-11 2.02E-10 31 538 "ADGRV1,RTKN,SLITRK1,NTNG1,GPAM,SYBU,PAAF1,ZNF365,CAPRIN2,TTLL9,KIF1B,ADHFE1,RND1,ZNF638,EML4,LEFTY2,FBXL16,NTSR2,SULT4A1,BTF3L4,KCNT2,PRKAB2,TOX,LRRTM3,SIRPA,ZC3H11A,RABGAP1L,KCNK2,KLRC2,ARHGEF10L,EPB41L2" MicroRNA hsa-miR-628-3p:mirSVR_highEffct hsa-miR-628-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.30E-12 4.49E-08 2.34E-11 2.15E-10 39 829 "SYT9,RTN3,ACTN2,ATAT1,KLHL32,RTN1,ADD3,ANXA7,EMC1,NPAS3,NDUFA5,SEPT3,PCDH11X,SYT4,GNAS,DDHD2,GPM6A,PTBP2,NUDT21,PCDH9,HEPACAM,SERPINE2,NEGR1,SLC25A27,BTF3L4,ACBD5,CRLS1,PPP3CB,PRKACB,USP54,MAPK10,SPIRE1,TOMM20,OCIAD1,KLRC3,PAK5,ZYG11B,RET,SEC61A2" MicroRNA hsa-miR-886-3p:mirSVR_lowEffct hsa-miR-886-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.31E-12 4.50E-08 2.34E-11 2.15E-10 29 473 "RABEPK,MBP,EXTL1,GOLGA7B,MOBP,TRIM46,ZNF365,ASPH,MTR,CADM3,NFASC,NELL1,ADHFE1,ACSBG1,GLS,HAP1,PTPN5,LEFTY2,FBXL16,P2RX7,IGSF21,CABP1,PPP2R5C,PRKCG,WBP1L,PLPPR4,DNM2,RAP1GAP,RAVER2" MicroRNA hsa-miR-940:mirSVR_highEffct hsa-miR-940:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.33E-12 4.51E-08 2.35E-11 2.16E-10 38 791 "MAG,GALNT13,SORCS1,CNIH2,CCDC80,PKNOX2,SLIT1,RCOR3,JPH4,FAM168A,SEMA4A,CAMSAP2,AKNA,PAH,LGI1,TPM3,DLGAP3,GDAP1L1,ZFYVE9,NRXN2,CAMKV,TJP2,CCDC136,POU3F2,CSF3R,RBPJ,BDNF-AS,CADM2,HP1BP3,PTPRE,NTM,DLG2,RAP1GAP,CAMK1G,RFX4,RNF220,CACNG7,RASGRP2" MicroRNA hsa-miR-4305:mirSVR_highEffct hsa-miR-4305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.38E-12 4.54E-08 2.36E-11 2.17E-10 30 506 "ATAT1,PLEKHG5,ERMN,FGR,NRG3,TTLL9,SLCO1C1,GNAS,NODAL,ACSL6,CACNB2,GRIA4,ATP13A2,CDH8,ARHGAP19,LGI1,MAGI1,TMPRSS5,ANLN,CRMP1,PPP2R5C,KCNT2,PHACTR3,PROX1,PTHLH,PCDH15,PID1,FAM13C,TTLL7,FGFBP3" MicroRNA hsa-miR-411:mirSVR_highEffct hsa-miR-411:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.57E-12 4.64E-08 2.41E-11 2.22E-10 31 540 "SLC44A5,LINC00461,BCAR3,PPFIA1,CACHD1,KIAA1614,ENKUR,SLCO1C1,VAMP1,SYT4,DDHD2,PTBP2,EML4,GRM3,ATP13A2,TPD52,JAM2,SULT4A1,SLC25A27,ACBD5,RNF14,PPP2R5C,VCAN,PLPP4,PUM1,TUBB2B,SYNC,C1orf109,RALGDS,RET,SLC39A12" MicroRNA "AAAGACA,MIR-511:MSigDB" "AAAGACA,MIR-511:MSigDB" MSigDB 8.59E-12 4.65E-08 2.42E-11 2.22E-10 19 190 "EYA1,SLITRK1,SCN4B,SORCS3,SMARCE1,ATP2B2,ZCCHC24,GAD2,GFAP,RGL1,CAMTA1,EML4,FNDC5,NXPH1,PMEPA1,SRGAP3,KCNMA1,VANGL2,ELAVL3" MicroRNA hsa-miR-6809-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.78E-12 4.75E-08 2.47E-11 2.26E-10 24 321 "FAM43B,TUBB4A,NLGN4X,DGKD,ASCL1,IGSF9B,MYBPC1,GFRA1,GPR26,CAMK2G,FBXL16,P2RX7,TNS1,CDH8,TLX1,GDAP1L1,NEGR1,PNKD,CADM2,KCNK2,NAV2,SH3GLB1,ABI2,ELAVL3" MicroRNA "CAGCTTT,MIR-320:MSigDB" "CAGCTTT,MIR-320:MSigDB" MSigDB 9.13E-12 4.94E-08 2.57E-11 2.35E-10 21 240 "SLITRK3,MIER1,TMEM108,PALLD,SON,CAB39,DNER,LMO3,NCDN,CAMTA1,CAMSAP2,CACNA1E,ZFP91,TPM3,NEGR1,NSD2,CDH20,TMEM255A,CALN1,DSCAM,PAK5" MicroRNA hsa-miR-1236:PITA hsa-miR-1236:PITA_TOP PITA 9.13E-12 4.94E-08 2.57E-11 2.35E-10 21 240 "NLGN4X,DOCK10,RCOR3,NCAM1,CACNA1E,CAMK2A,CAMK2G,FBXL16,CELF3,RBFOX2,NRXN1,NSD2,FAM131B,BRINP3,SRGAP3,KCNN3,DLG3,WIPF2,SLC17A6,PAK5,RBM12" MicroRNA hsa-miR-2909:mirSVR_highEffct hsa-miR-2909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.81E-12 5.31E-08 2.75E-11 2.53E-10 28 444 "ACER3,KLHL32,TUBB4A,NRG3,MEGF11,SON,ZNF638,DCLK2,UNC5D,CACNB2,SYT6,TJP1,TLL2,PDE3B,PIRT,BEST3,CASC2,CADM1,BEST1,RGS6,CTNND1,PTPRD,PCDH15,PEX5,SNX27,DLG2,RFX5,CBLN2" MicroRNA hsa-miR-623:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.88E-12 5.35E-08 2.77E-11 2.54E-10 21 241 "ADCYAP1R1,TMEM156,ASIC4,BCAN,CACHD1,LRRC55,ZCCHC24,SMOC1,ACSBG1,MYRF,CACNA1A,TCF7L2,CAMK2G,SYT6,PADI2,SEZ6L,TMEFF2,TLX1,PHKG1,CHD5,ZYG11B" MicroRNA hsa-miR-3180-3p:mirSVR_highEffct hsa-miR-3180-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.90E-12 5.36E-08 2.78E-11 2.55E-10 16 126 "SLITRK1,ST3GAL3,LGI3,TNIK,NKX2-2,KAZN,DDR1,INA,FNDC5,DLGAP3,KIAA1549L,CABP1,NSD2,ANKS1B,RFX4,RNF220" MicroRNA hsa-miR-150:mirSVR_highEffct hsa-miR-150:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.00E-11 5.43E-08 2.81E-11 2.58E-10 38 796 "ACER3,MDM4,WAC,CNIH2,PPFIA1,PKP4,APC,API5,SLC1A6,DACH2,SMARCE1,TMEM108,GABBR1,B3GALT2,NCAM1,STOX1,GLS,DDHD2,ZEB1,PTBP2,TPM3,ZNF384,NEGR1,FTO,FEZ2,MICAL2,PRKACB,IGSF1,PROX1,MASP1,GON4L,PTPRE,USH1C,PHC2,VWA5A,CBLN2,OLIG2,EPB41" MicroRNA hsa-miR-346:mirSVR_highEffct hsa-miR-346:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-11 5.46E-08 2.83E-11 2.60E-10 27 413 "SYT9,EXTL1,CHST15,TOMM40L,GOLGA7B,ERICH3,PKP4,LRRC4C,SORCS3,ATP1A2,CADM3,KIF1B,ALDH1L1,ERBIN,ADHFE1,ANO4,CACNB2,PTPN5,JAM2,CCDC136,NXPH1,SF1,SNCAIP,NTM,ABCC9,ZNF248,RPRD1A" MicroRNA hsa-miR-580:PITA hsa-miR-580:PITA_TOP PITA 1.07E-11 5.78E-08 2.99E-11 2.74E-10 24 324 "TMEM74,NLGN4X,GPR158,LRRC7,SOX6,GPAM,CACHD1,SPHKAP,SOX5,NCAM1,RGL1,CAMTA1,CAMSAP2,ANO4,CAMK2A,PSD3,OPCML,MAGI1,MED1,PPP2R5C,ATRNL1,FMN2,PUM1,GOPC" MicroRNA hsa-miR-569:PITA hsa-miR-569:PITA_TOP PITA 1.07E-11 5.79E-08 2.99E-11 2.74E-10 21 242 "EYA1,ADD3,SEMA6A,SOX5,NFASC,NCAM1,CLASP2,GNG4,BTRC,CDC42,RAB39A,LRRTM3,KCNA4,PTPRZ1,KCNK1,SNX27,TMEM255A,PLEKHB2,SLC39A12,SH3GLB1,LPAR6" MicroRNA hsa-miR-505:PITA hsa-miR-505:PITA_TOP PITA 1.07E-11 5.79E-08 2.99E-11 2.74E-10 21 242 "ABAT,ACTN2,EYA1,SNX30,SOX6,SLC8A3,MYT1L,SOX5,SEPT3,ARHGEF7,ADGRL3,GPM6A,DAAM2,HMGB1,CADM1,POU3F4,SF1,PPP3CB,KIAA0408,KCNMA1,SLC4A10" MicroRNA hsa-miR-1274a:PITA hsa-miR-1274a:PITA_TOP PITA 1.16E-11 6.26E-08 3.23E-11 2.97E-10 17 148 "SNX30,SCN3A,LRRTM4,MYT1L,RGL1,CACNB2,RFFL,HNRNPK,NRXN1,MED1,FEZ1,KCNA1,PTPRD,SNX27,FAM135B,ARHGAP12,SLC4A10" MicroRNA hsa-miR-939:PITA hsa-miR-939:PITA_TOP PITA 1.17E-11 6.36E-08 3.28E-11 3.01E-10 14 90 "CSMD2,CNIH2,WDTC1,CADM3,CPLX2,NFASC,BCL2L2,NCDN,CACNA1A,GRIA1,DCLK1,NRXN2,MED1,PHC2" MicroRNA hsa-miR-1266:mirSVR_highEffct hsa-miR-1266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-11 6.55E-08 3.38E-11 3.10E-10 33 617 "ZFYVE27,SYT9,ARID1A,SORCS1,AMER2,LRRTM4,BCAS1,NSG2,CADPS,ASTN1,EIF4G3,GFAP,CAMSAP2,ANO4,PTBP2,NUDT21,AIFM1,PAH,PDE1C,P2RY12,MED1,KIAA0513,ANKS1B,PRDM2,COPS7A,KCNA6,KCNK1,NKAIN1,SLC25A48,DTNA,BSDC1,OLIG2,SEZ6" MicroRNA hsa-miR-5011-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-11 6.63E-08 3.42E-11 3.14E-10 34 653 "ACER3,GRAMD1B,NLGN4X,CCDC80,LRRC55,MYBPC1,WDTC1,SOX5,NFIA,GRID1,GRIK3,OPCML,CADM1,NEGR1,MEAF6,SLC25A27,PRRX1,ACBD5,PPP2R5C,DOCK7,PUM1,PROX1,ZBTB16,PMEPA1,LRP8,PTPRD,KCNK1,KCNN3,RAB5B,L1CAM,SSPN,ABI2,FGFBP3,RCAN2" MicroRNA hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA_TOP PITA 1.25E-11 6.75E-08 3.48E-11 3.19E-10 23 298 "ADD3,BCAR3,ELMOD1,CNIH2,NTNG1,TACC2,SLC1A2,CCDC88A,PHYHIPL,NEUROD1,NFIA,BTRC,ZEB1,EML4,REPS2,DCLK1,PDE4B,SERPINE2,FAT3,NXPH1,PTPRZ1,ATL1,SH3GLB1" MicroRNA hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA_TOP PITA 1.25E-11 6.75E-08 3.48E-11 3.19E-10 23 298 "ADD3,BCAR3,ELMOD1,CNIH2,NTNG1,TACC2,SLC1A2,CCDC88A,PHYHIPL,NEUROD1,NFIA,BTRC,ZEB1,EML4,REPS2,DCLK1,PDE4B,SERPINE2,FAT3,NXPH1,PTPRZ1,ATL1,SH3GLB1" MicroRNA hsa-miR-532-3p:TargetScan hsa-miR-532-3p TargetScan 1.25E-11 6.77E-08 3.48E-11 3.20E-10 21 244 "MDM4,ADCYAP1R1,HPCAL4,PDZD4,BCAS1,LRRC55,EIF4G3,SCN3B,CADM3,NMNAT2,NFASC,GFRA1,NRXN2,CAMKV,NEGR1,LRRTM3,KCND3,BSDC1,PIANP,ABI2,ELAVL3" MicroRNA hsa-miR-325:mirSVR_highEffct hsa-miR-325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-11 6.81E-08 3.50E-11 3.21E-10 27 417 "LGR4,WAC,USP28,ITSN1,NRG3,TNIK,ILDR2,DNER,NDUFA5,KLHL4,ANO4,CECR2,GRIA4,MAEL,BEST3,PFKFB3,CADM1,SULT4A1,ACBD5,PRKAB2,RAB39A,DNAH9,PAK5,RET,ZNF248,TTLL7,SYT15" MicroRNA hsa-miR-874:mirSVR_highEffct hsa-miR-874:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.26E-11 6.81E-08 3.50E-11 3.21E-10 27 417 "GALNT13,SORCS1,MOG,SESN3,PAAF1,YPEL4,PHYHIPL,MEGF11,PCDH11X,BTRC,ADGRL3,CACNB2,GRIA4,RFFL,GRIK2,AIFM1,CIART,PLEKHB1,BEST1,COL9A2,PPP3CB,COPS7A,MAGI2,PLEKHB2,ATG16L1,PAK5,ARHGAP12" MicroRNA hsa-miR-1274a:mirSVR_highEffct hsa-miR-1274a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-11 6.88E-08 3.54E-11 3.25E-10 32 583 "ATAT1,CSMD2,KLHL32,TESK2,LRRTM4,SFPQ,CACHD1,ASPH,KIF1B,SPART,RGL1,ZNF638,TBX15,CACNB2,LGI1,CASC2,NRXN1,FEZ1,MICAL2,ATRNL1,CTNND1,ZNF385B,BLOC1S6,ZC3H11A,KCNJ9,SNX27,HS3ST4,RAD52,FAM135B,GPR61,ARHGAP12,EPB41L2" MicroRNA hsa-miR-198:PITA hsa-miR-198:PITA_TOP PITA 1.29E-11 6.98E-08 3.59E-11 3.29E-10 17 149 "RIMKLA,PKNOX2,ARFGAP2,SCMH1,ATP1A3,JPH4,CAMK2G,DDR2,NRXN1,PRKAB2,PSD,DNAJC6,SRGAP3,DLG3,DPP6,DBX2,FAM135B" MicroRNA hsa-miR-654-3p:PITA hsa-miR-654-3p:PITA_TOP PITA 1.30E-11 7.06E-08 3.62E-11 3.32E-10 20 219 "SYNDIG1,FGF14,SORBS1,SLC1A2,SLC8A2,RCOR3,CADM3,AHCYL1,CPLX2,OPCML,TJP1,TUB,PACSIN1,NXPH1,MED1,SF1,CA10,CADM2,ELMO1,SNX27" MicroRNA hsa-miR-299-3p:PITA hsa-miR-299-3p:PITA_TOP PITA 1.35E-11 7.30E-08 3.75E-11 3.44E-10 15 109 "SLC25A25,SEMA6A,ANK1,MADD,MYT1L,SOX5,CACNB2,OPCML,CDC42,HMGB1,DLGAP3,PRRX1,ITGAV,KCNMA1,DLG2" MicroRNA hsa-miR-544b:mirSVR_highEffct hsa-miR-544b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-11 7.38E-08 3.79E-11 3.47E-10 31 550 "EMID1,NDRG2,KLHL32,SORCS1,ITSN1,JAKMIP3,MSRA,B3GAT1,SON,RGL1,ADHFE1,GNG3,MYRF,GRIA2,CRB1,AIFM1,HEPACAM,CAMKV,PNKD,SNCAIP,PPP3CB,PKN2,EDRF1,CADM2,SLC25A48,DPP6,DTNA,SLC6A15,PHC2,SSPN,EN2" MicroRNA hsa-miR-220b:mirSVR_highEffct hsa-miR-220b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-11 7.77E-08 3.99E-11 3.66E-10 33 621 "RBM10,IL17D,KCNIP2,GRAMD1B,ADORA3,LRRC7,PPM1E,DACH2,DNAH17,NRG3,ZNF302,SMOC1,GFAP,NKX2-2,GOLGB1,CECR2,GRIA2,GRIA4,PDE4B,HNRNPK,OPALIN,P2RY12,NKAIN4,FEZ2,CTNND1,PRDM2,SMG7,SV2A,GOPC,RFX4,ARHGEF10L,SSPN,GPR61" MicroRNA "TTTGCAG,MIR-518A-2:MSigDB" "TTTGCAG,MIR-518A-2:MSigDB" MSigDB 1.63E-11 8.80E-08 4.51E-11 4.14E-10 19 197 "DSCAML1,ANK2,DOCK10,SORBS1,EIF4G3,SPART,DCAF5,CAMTA1,TCF12,HMGB1,PACSIN1,SF1,PRKAB2,CA10,PMEPA1,PLPPR4,PLEKHB2,FAM135B,EPB41L1" MicroRNA hsa-miR-1225-5p:mirSVR_highEffct hsa-miR-1225-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-11 9.04E-08 4.63E-11 4.25E-10 26 391 "CSMD3,SLITRK1,MOBP,PKP4,BCAN,NLGN1,SALL3,SPART,GFAP,GLS,PCDH11X,MMD2,GRIA4,LINC01102,BEST1,DZIP3,PTCH1,CA10,PTHLH,PTPRD,KCNK1,KCNMA1,RAP1GAP,RGR,INSYN2,ABI2" MicroRNA hsa-miR-370:PITA hsa-miR-370:PITA_TOP PITA 1.71E-11 9.26E-08 4.74E-11 4.35E-10 18 174 "ASIC1,ANK3,CNIH2,ST3GAL3,AQP4,B3GALT2,NFASC,CLASP2,DCAF5,NCDN,PCDH11X,MAGI1,CCDC136,RIMS4,ARHGEF4,SMG7,KCNJ11,PHC2" MicroRNA "GCAAAAA,MIR-129:MSigDB" "GCAAAAA,MIR-129:MSigDB" MSigDB 1.71E-11 9.26E-08 4.74E-11 4.35E-10 18 174 "APC,JAKMIP3,EIF4G3,MYT1L,CAMTA1,ADGRL3,PSD3,PAX6,FNDC5,HMGB1,HNRNPK,NRXN2,SLC25A27,CTNND1,TOX,PMEPA1,PTPRZ1,SLC17A6" MicroRNA hsa-miR-149-5p:TargetScan hsa-miR-149-5p TargetScan 1.71E-11 9.27E-08 4.74E-11 4.35E-10 25 361 "ACER3,ADCYAP1R1,CACHD1,KIAA1614,GPR153,B3GAT1,BCL2L2,NCDN,PHLDB1,GPR88,FBXL16,GUCY1A2,REPS2,ARHGAP19,IGFN1,CHRM1,RIMS4,JAKMIP2,KCNJ10,KCNN3,KIF2A,RAB3IL1,RNF220,PLEKHO1,EPB41L1" MicroRNA hsa-miR-365*:mirSVR_highEffct hsa-miR-365*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-11 9.42E-08 4.82E-11 4.42E-10 28 455 "LDLRAD3,UNC79,C1orf61,GPAM,ARHGAP5,PDE8B,SLCO1A2,RCOR3,AHCYL1,SPART,RND1,GRID1,INA,ZFP91,PLEKHB1,FTO,C11orf49,P2RY12,ACBD5,PLCH2,PRKCZ,PRTFDC1,PTPRE,PLPPR4,DLG2,RET,PHC2,SLC4A10" MicroRNA hsa-miR-711:mirSVR_highEffct hsa-miR-711:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-11 1.01E-07 5.17E-11 4.74E-10 26 393 "ACLY,SLITRK1,FGF14,TRIM46,ITSN1,RUFY2,B3GAT1,TTLL9,GANAB,ZNF638,CAMTA1,WWC1,CECR2,GRIA2,GRIA4,SPX,GUCY1A2,PRMT8,CNRIP1,PTPA,DOCK7,CTNND1,ECE2,HP1BP3,PEX5,RNF220" MicroRNA hsa-miR-103-as:mirSVR_highEffct hsa-miR-103-as:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.03E-11 1.10E-07 5.61E-11 5.14E-10 28 458 "RTN3,KCNIP2,ADORA3,ST3GAL3,RPH3A,SNAP25,TTLL9,GART,NAP1L2,CAMTA1,GRIA2,GRIA4,TJP1,AIFM1,SEZ6L,PRMT8,CADM1,RGS6,KCNT2,DOCK7,NRSN1,BDNF-AS,NTM,PCDH15,KIF2A,GNE,JMJD1C,SEC61A2" MicroRNA hsa-miR-1245:PITA hsa-miR-1245:PITA_TOP PITA 2.03E-11 1.10E-07 5.62E-11 5.15E-10 16 132 "CSMD3,NLGN1,SLC1A2,RCOR3,NUDT21,INA,CADM1,OSBPL3,SYNC,CSDE1,KCNA1,KCNK2,WIPF2,TMEM255A,RBM12,RCAN2" MicroRNA hsa-miR-4644:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-11 1.16E-07 5.89E-11 5.41E-10 21 251 "DPF1,ZFYVE27,ARID1A,PDZD4,SFMBT2,PKNOX2,CCDC88A,C10orf105,WDTC1,NEUROD1,DCLK2,TMEM9,TMPRSS5,PFKFB3,CADM1,SF1,PTPA,MICAL2,ZC3H11A,RAB5B,ELAVL3" MicroRNA hsa-miR-147b:mirSVR_lowEffct hsa-miR-147b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-11 1.23E-07 6.30E-11 5.78E-10 24 336 "ACER3,WLS,TOMM40L,GPR158,MT3,LGI3,ARHGEF7,MMD2,VXN,GRM3,PAX6,TMPRSS5,CHGA,CASC2,TJP2,FTO,SLC25A27,NSD2,TENM4,TOMM20,SUSD4,SLC6A15,RPE65,EPB41L1" MicroRNA hsa-miR-1275:PITA hsa-miR-1275:PITA_TOP PITA 2.28E-11 1.24E-07 6.30E-11 5.78E-10 16 133 "ARID1A,PKNOX2,CACNA1A,ATF7,GRIN1,FBXL16,CELF3,NRXN2,POU3F2,MED1,CA10,DPP6,INSYN2,PHC2,EFNA3,ELAVL3" MicroRNA hsa-miR-578:PITA hsa-miR-578:PITA_TOP PITA 2.43E-11 1.31E-07 6.69E-11 6.14E-10 24 337 "MRVI1,ADD3,ANK3,ITSN1,PPM1E,TACC2,AQP4,SON,RGL1,GPM6A,VWC2,CAMK2G,GRIA2,GRID1,TNS1,PKN2,KCNK2,DLG2,PID1,TMEM255A,SLC17A6,ABI1,ELAVL3,RCAN2" MicroRNA "CTATGCA,MIR-153:MSigDB" "CTATGCA,MIR-153:MSigDB" MSigDB 2.52E-11 1.37E-07 6.95E-11 6.38E-10 19 202 "TESK2,SFPQ,ANK1,USP28,APC,SLC1A2,ARHGAP5,TAGLN3,SNAP25,NEUROD1,CAMK2G,MAGI1,ZFYVE9,CCSER2,DPYSL5,PRDM2,KCNA6,NAV2,EFNA3" MicroRNA hsa-miR-410-3p:TargetScan hsa-miR-410-3p TargetScan 2.66E-11 1.44E-07 7.34E-11 6.73E-10 27 431 "EPS8,GRAMD1B,MAGI3,MIER1,ARHGAP5,PDE8B,ATP2B2,C11orf87,DCAF5,PRUNE2,NUDT21,GRIA2,GUCY1A2,PCDH8,HMGB1,BTF3L4,PRRX1,OSBPL3,CTNND1,PMEPA1,DLG3,CALN1,ATG16L1,ATN1,DTNA,BSDC1,ELAVL4" MicroRNA hsa-miR-542-5p:mirSVR_lowEffct hsa-miR-542-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-11 1.49E-07 7.56E-11 6.93E-10 28 464 "TTYH1,C1orf194,ACHE,ECSIT,CLIP1,TMEM156,FGF14,TMEM108,ADGRA1,SNCB,ILDR2,TTLL9,NCAM1,GANAB,ADAMTS8,SPX,TGFBR3,IGFN1,PDE4B,PLXNB3,NSD2,MFSD4A,PPP2R5C,NCAN,PRDM2,PTPRE,PEX5,SNX27" MicroRNA hsa-miR-135a*:mirSVR_highEffct hsa-miR-135a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-11 1.49E-07 7.57E-11 6.95E-10 34 673 "SYT9,ECSIT,SCN3A,MOBP,ZNF365,ARHGAP5,SLC8A3,ASCL1,SPART,ZNF302,PHLDB1,NEUROD1,SYT4,CAMK2G,GUCY1A2,PADI2,MAGI1,PRMT8,GDAP1L1,NOMO2,PMP2,ACBD5,MFSD4A,POU3F2,CRLS1,USP54,IGSF1,KIAA0513,LRRTM3,CSDE1,KLRC3,GOPC,SLC4A10,EN2" MicroRNA hsa-miR-219-1-3p:mirSVR_highEffct hsa-miR-219-1-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-11 1.57E-07 8.00E-11 7.34E-10 36 749 "SERPINA3,IL17D,SLITRK1,SLITRK3,ASPH,FYN,MEGF11,KIF21B,NFASC,NCAM1,ZNF302,ZNF638,DCLK2,ROBO3,GRIA1,OLR1,AIFM1,MAEL,TPD52,PRMT8,CADM1,CCDC136,CNTN1,RNF14,MICAL2,VCAN,CTNND1,PLPPR1,LRP8,PTPRE,KCNMA1,KCNN3,SLC17A6,CAMK1G,YY1AP1,SEZ6" MicroRNA hsa-miR-615-3p:mirSVR_lowEffct hsa-miR-615-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-11 1.60E-07 8.12E-11 7.45E-10 23 311 "BCAN,ARFGAP2,SLC8A2,ASCL1,KIF21B,IDI2-AS1,HEPN1,RGL1,AJAP1,CACNB2,NRGN,PTBP2,BRSK2,ASIC3,CASC2,PLXNB3,RGS6,PRKCG,PRKCZ,DLG2,FAM66C,ATN1,DBX2" MicroRNA hsa-miR-490-3p:mirSVR_highEffct hsa-miR-490-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.00E-11 1.62E-07 8.24E-11 7.56E-10 29 499 "SDE2,ACTN2,KCNIP2,ITSN1,DOCK10,MAGI3,SHTN1,PKNOX2,SHANK2,SMARCE1,NRG3,DKK3,SOX5,NEK6,GLS,TMEM136,GRIA1,GRIA2,TPD52,MAGI1,A2ML1,RBPJ,RAB39A,PRDM2,SMG7,AK5,RABGAP1L,RBM12,BAALC" MicroRNA "ACATTCC,MIR-1:MSigDB" "ACATTCC,MIR-1:MSigDB" MSigDB 3.01E-11 1.63E-07 8.27E-11 7.59E-10 22 283 "SLC25A25,ADAR,FGF14,DGKZ,SLC8A2,SNAP25,USP33,CPLX2,PSD3,TGFBR3,CDC42,TPM3,HNRNPK,GDAP1L1,MED1,RIMS4,WBP1L,PLPPR4,BSDC1,PHC2,BSCL2,RCAN2" MicroRNA hsa-miR-21-5p:TargetScan hsa-miR-21-5p TargetScan 3.01E-11 1.63E-07 8.27E-11 7.59E-10 22 283 "FOXG1,NPAS3,C11orf87,NFIA,PSRC1,RFFL,OLR1,KCNK10,BEST3,HNRNPK,CADM1,NEGR1,FTO,FAT3,ACBD5,RBPJ,MAPK10,CADM2,KCNA1,RTN4,RPRD1A,RAVER2" MicroRNA "ACATTCC,MIR-206:MSigDB" "ACATTCC,MIR-206:MSigDB" MSigDB 3.01E-11 1.63E-07 8.27E-11 7.59E-10 22 283 "SLC25A25,ADAR,FGF14,DGKZ,SLC8A2,SNAP25,USP33,CPLX2,PSD3,TGFBR3,CDC42,TPM3,HNRNPK,GDAP1L1,MED1,RIMS4,WBP1L,PLPPR4,BSDC1,PHC2,BSCL2,RCAN2" MicroRNA hsa-miR-362-3p:mirSVR_highEffct hsa-miR-362-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.02E-11 1.63E-07 8.28E-11 7.59E-10 36 750 "TOMM40L,LRRTM4,FGF14,ACTL6B,BCAS1,PAAF1,MIER1,ASPH,EIF4G3,DKK3,NDUFA5,DCAF5,PCDH11X,SYT4,DCLK2,BTRC,ZEB1,PTBP2,P2RX7,MAEL,PDYN,CRMP1,RNF14,PRKACB,EDRF1,GON4L,COPS7A,OLFM3,KCNC1,ARNT2,KCNMA1,GNE,RGS10,ARHGEF10L,SYT15,CBLN2" MicroRNA hsa-miR-1259:PITA hsa-miR-1259:PITA_TOP PITA 3.15E-11 1.71E-07 8.64E-11 7.92E-10 23 312 "SNX30,LRRC7,SLC1A2,ARHGAP5,PHYHIPL,ERBIN,NEUROD1,PCDH11X,CAMTA1,PTBP2,PCDH9,HMGB1,PRRX1,MED1,KCNT2,ATRNL1,PROX1,CADM2,LRP8,DLG3,ARHGAP12,SLC4A10,RCAN2" MicroRNA hsa-miR-770-5p:PITA hsa-miR-770-5p:PITA_TOP PITA 3.22E-11 1.74E-07 8.81E-11 8.09E-10 16 136 "ANK3,MAGI3,ARHGAP5,EIF4G3,NMNAT2,GRIA2,NMT2,BTF3L4,NXPH1,TMCC2,KCNJ11,KCNK1,SLC17A6,GOPC,ARHGAP12,RCAN2" MicroRNA hsa-miR-590-5p:TargetScan hsa-miR-590-5p TargetScan 3.23E-11 1.75E-07 8.84E-11 8.11E-10 22 284 "FOXG1,NPAS3,C11orf87,NFIA,PSRC1,RFFL,OLR1,KCNK10,BEST3,HNRNPK,CADM1,NEGR1,FTO,FAT3,ACBD5,RBPJ,MAPK10,CADM2,KCNA1,RTN4,RPRD1A,RAVER2" MicroRNA hsa-miR-409-5p:TargetScan hsa-miR-409-5p TargetScan 3.34E-11 1.81E-07 9.15E-11 8.39E-10 14 97 "ABAT,GALNT13,ANK3,KIF1B,DCAF5,CAMTA1,LRTM2,LRRTM3,DNAJC6,LRP8,KCNA1,KCND3,PIANP,CBLN2" MicroRNA hsa-miR-934:PITA hsa-miR-934:PITA_TOP PITA 3.34E-11 1.81E-07 9.15E-11 8.39E-10 14 97 "WAC,SLC1A2,RCOR3,ZCCHC24,SYT4,DCLK1,MAGI1,NEGR1,CEP170,KCNA1,KCNMA1,DLG3,INSYN2,EPB41L1" MicroRNA hsa-miR-450a:mirSVR_lowEffct hsa-miR-450a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-11 1.86E-07 9.39E-11 8.61E-10 26 404 "MEG3,GPR158,SGIP1,ANK3,ITSN1,SESN3,AQP4,SLC1A6,COLGALT2,GNAS,GRIA2,TJP1,LGI1,NRXN1,UBTF,OSBPL3,KIAA1755,TOX,PTPRZ1,TMCC2,KCNK2,DLG2,PID1,SLC17A6,ZYG11B,ELAVL4" MicroRNA hsa-miR-4446-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-11 1.86E-07 9.40E-11 8.62E-10 20 231 "ACTN2,ADCYAP1R1,CCDC80,ZCCHC24,NPAS3,SMOC1,DCAF5,ACSBG1,NFIA,GPR26,SYT6,TNS1,TMEFF2,NEGR1,RGS6,CHD5,RBPJ,PTPRE,ZYG11B,VANGL2" MicroRNA hsa-miR-3177:mirSVR_lowEffct hsa-miR-3177:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.46E-11 1.87E-07 9.44E-11 8.66E-10 29 502 "EYA1,GPR158,ASIC4,GPAM,SORBS1,ZNF365,KIAA1614,ASTN1,ARPP21,GJB1,DCLK2,NEU4,CYB561A3,CD81,TNS1,PTGDR2,PRMT8,PLXNB3,IFFO1,NSD2,ATRNL1,PRKCG,COPS7A,KCNA6,PTPRE,TMCC2,KCNK1,RALGDS,ZYG11B" MicroRNA hsa-miR-5193:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-11 1.87E-07 9.44E-11 8.66E-10 22 285 "CHST15,PKNOX2,SLIT1,SMARCE1,C10orf105,TMEM151A,NKX2-2,CACNB2,TCF7L2,GRID1,GRIK3,LEFTY2,HMGB1,TLX1,SLC22A6,ZBTB16,DPYSL5,PTAFR,TMCC2,KCNJ11,FAM13C,VWA5A" MicroRNA hsa-miR-19a-3p:Functional MTI Functional MTI miRTarbase 3.48E-11 1.89E-07 9.51E-11 8.73E-10 31 571 "SDE2,CLIP1,WAC,SOX6,SESN3,CCDC80,GPAM,MIER1,CAPRIN2,CAB39,SPART,SMOC1,RGL1,NFIA,VAMP1,CAMTA1,CAMSAP2,PRUNE2,PTBP2,TF,TNFRSF1B,ZFYVE9,CCSER2,BTF3L4,ACBD5,PRKACB,PMEPA1,CEP170,RAB5B,ATG16L1,ARHGAP12" MicroRNA hsa-miR-611:mirSVR_lowEffct hsa-miR-611:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.64E-11 1.97E-07 9.93E-11 9.11E-10 27 437 "RTN3,MOBP,ASRGL1,ST3GAL3,MADD,LHFPL4,ADAM15,NCAM1,SYT4,ANO4,CECR2,GRIA2,TNFRSF1B,LGI1,TJP2,PLXNB3,PPP2R5C,RAB39A,ANKS1B,CSDE1,C1orf109,NTM,TMCC2,SLC17A6,RALGDS,LMO1,RPE65" MicroRNA hsa-miR-4252:mirSVR_highEffct hsa-miR-4252:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.73E-11 2.02E-07 1.02E-10 9.33E-10 32 608 "TTYH1,SYT9,RCSD1,NDRG2,F3,TOMM40L,FOXG1,ST3GAL3,BCAS1,ARPP21,KIF1B,ADHFE1,ARHGEF7,ZNF638,NODAL,GPM6A,TCF12,GRIA2,P2RX7,AIFM1,TMEM257,PCDH9,TMEFF2,RGS6,DOCK7,PKN2,PSMD13,GNE,FAM13C,ZYG11B,RFX4,ARHGAP12" MicroRNA hsa-miR-296-3p:mirSVR_highEffct hsa-miR-296-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.80E-11 2.06E-07 1.04E-10 9.49E-10 29 504 "TTYH1,ATAT1,ERMN,CHST15,ERICH3,CADPS,SCMH1,ASTN1,NRG3,JPH4,FXYD6,DDHD2,UNC5D,GRM3,LINC00839,PDE2A,FNDC5,CASC2,SERPINE2,CNTN1,KIAA1755,CTNND2,MAPK10,LRRTM3,PTCH1,JAKMIP2,PTPRD,C12orf4,DTNA" MicroRNA hsa-miR-139-3p:mirSVR_lowEffct hsa-miR-139-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.08E-11 2.21E-07 1.11E-10 1.02E-09 28 472 "LDLRAD3,CSMD2,MADD,SLC8A2,CADPS,DLL3,ASPH,ASTN1,TMEM108,FXYD6,NEUROD1,ZNF638,SYT6,GRIA2,GRIA4,GPR88,VWCE,CDC42,PRMT8,UBTF,SULT4A1,PPP2R5C,PRKCZ,OLIG1,ZYG11B,SIDT2,FGFBP3,TMEM100" MicroRNA hsa-miR-574-3p:mirSVR_lowEffct hsa-miR-574-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.19E-11 2.27E-07 1.14E-10 1.05E-09 24 346 "FHL1,MADD,NAXD,NCAM1,NDUFA5,DCAF5,ZEB1,CAMK2G,REPS2,PDE2A,NSD2,BTBD17,CHD1L,VCAN,PRKCZ,ARHGEF4,WBP1L,SPIRE1,TOMM20,DNM2,DPP6,RASGRF1,ARHGEF10L,RCAN2" MicroRNA "AGCACTT,MIR-526B:MSigDB" "AGCACTT,MIR-526B:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-520D:MSigDB" "AGCACTT,MIR-520D:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-520C:MSigDB" "AGCACTT,MIR-520C:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-302A:MSigDB" "AGCACTT,MIR-302A:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-520A:MSigDB" "AGCACTT,MIR-520A:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-93:MSigDB" "AGCACTT,MIR-93:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-372:MSigDB" "AGCACTT,MIR-372:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-373:MSigDB" "AGCACTT,MIR-373:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-302B:MSigDB" "AGCACTT,MIR-302B:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-520E:MSigDB" "AGCACTT,MIR-520E:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-520B:MSigDB" "AGCACTT,MIR-520B:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-302D:MSigDB" "AGCACTT,MIR-302D:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA "AGCACTT,MIR-302C:MSigDB" "AGCACTT,MIR-302C:MSigDB" MSigDB 4.33E-11 2.35E-07 1.17E-10 1.08E-09 23 317 "ANK2,SLITRK3,SLC6A9,ATP2B2,MYT1L,NPAS3,LMO3,RGL1,NEUROD1,CAMTA1,MYRF,OPCML,ZFP91,PRRX1,TOX,DPYSL5,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5" MicroRNA hsa-miR-297:PITA hsa-miR-297:PITA_TOP PITA 4.34E-11 2.35E-07 1.17E-10 1.08E-09 20 234 "ACLY,CLIP1,API5,CCDC88A,EIF4G3,NEUROD1,CAMTA1,ANO4,TCF12,GRIA2,PCSK2,NRXN1,NSD2,PPP2R5C,CTNND2,SYNC,CA10,CADM2,RNF220,ELAVL4" MicroRNA hsa-miR-1278:PITA hsa-miR-1278:PITA_TOP PITA 4.36E-11 2.36E-07 1.18E-10 1.08E-09 18 184 "EYA1,RTN1,DOCK10,TACC2,PKNOX2,EIF4G3,ERBIN,SYT4,TCF12,GRIA2,GUCY1A1,TMEM257,KIAA1549L,KIAA0408,LRRTM3,KCNA1,GOPC,ST8SIA3" MicroRNA hsa-miR-504-5p.1:TargetScan hsa-miR-504-5p.1 TargetScan 4.36E-11 2.36E-07 1.18E-10 1.08E-09 18 184 "EYA1,GRAMD1B,HPCAL4,ANK3,ANXA7,LHFPL4,BCL2L2,CNTN2,PTBP2,RBFOX2,FTO,BEST1,ATCAY,RIMS3,KCNJ11,RPRD1A,ELAVL4,RCAN2" MicroRNA hsa-miR-4293:mirSVR_highEffct hsa-miR-4293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.58E-11 2.48E-07 1.24E-10 1.13E-09 29 508 "SDE2,ACER3,CLIP1,GALNT13,PPFIA1,ITSN1,SHTN1,SLC1A6,ARHGAP5,CAPRIN2,SORCS3,USP33,B3GALT2,TNIK,DDHD2,TCF12,CYB561A3,CRB1,MAEL,HPS5,MAGI1,FMN2,BLOC1S6,KCNK2,DNM2,FAM66C,DPP6,DTNA,SLC6A15" MicroRNA hsa-miR-564:mirSVR_lowEffct hsa-miR-564:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.80E-11 2.60E-07 1.29E-10 1.19E-09 29 509 "RABEPK,SYT9,SYNDIG1,EYA1,LINC00461,MOBP,TRIM46,BCO1,SLC8A3,TMEM108,PRUNE2,TCF7L2,PCDH8,PCDH9,DCLK1,PRMT8,C11orf49,CABP1,SPATA6,MASP1,PTCH1,HP1BP3,COPS7A,SMG7,TMCC2,KCNJ11,KCNK1,SLC25A48,NUP214" MicroRNA hsa-miR-339-5p:mirSVR_highEffct hsa-miR-339-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.26E-11 2.85E-07 1.42E-10 1.30E-09 29 511 "PPFIA1,ITSN1,SORBS1,SFMBT2,URGCP,SOX1,DDHD2,CNDP1,GRIK4,GRM3,DAAM2,NRXN1,PLXNB3,NXPH1,MFSD4A,PPP3CB,GON4L,PLPPR5,ZNF385B,COPS7A,MAGI2,NTM,RABGAP1L,RAB3IL1,ABCC9,FAM135B,INSYN2,SLC4A10,UEVLD" MicroRNA hsa-miR-1200:PITA hsa-miR-1200:PITA_TOP PITA 5.31E-11 2.87E-07 1.43E-10 1.31E-09 24 350 "LGR4,TOMM40L,SOX6,SH3GL2,PPM1E,SORBS1,YPEL4,SMARCE1,BCL2L2,ARHGEF7,CAMTA1,CAMSAP2,UNC5D,EML4,RBFOX2,PDE3B,PDE4B,PKN2,CTNND2,WIPF2,L1CAM,PHC2,ABI2,EPB41" MicroRNA hsa-miR-6769b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-11 2.91E-07 1.45E-10 1.33E-09 19 211 "SERPINA3,ACTN2,ASIC4,SMARCE1,ACSBG1,TMEM151B,GRID1,TGFBR3,CDH8,PTGDR2,GPR37L1,TMPRSS5,GDAP1L1,KIAA0408,DPYSL5,SMG7,TMCC2,KCNN3,ABI2" MicroRNA hsa-miR-4723-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.84E-11 3.16E-07 1.57E-10 1.44E-09 19 212 "SERPINA3,ACTN2,ASIC4,SMARCE1,ACSBG1,TMEM151B,GRID1,TGFBR3,CDH8,PTGDR2,GPR37L1,TMPRSS5,GDAP1L1,KIAA0408,DPYSL5,SMG7,TMCC2,KCNN3,ABI2" MicroRNA hsa-miR-3183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.84E-11 3.16E-07 1.57E-10 1.44E-09 19 212 "SERPINA3,ACTN2,ASIC4,SMARCE1,ACSBG1,TMEM151B,GRID1,TGFBR3,CDH8,PTGDR2,GPR37L1,TMPRSS5,GDAP1L1,KIAA0408,DPYSL5,SMG7,TMCC2,KCNN3,ABI2" MicroRNA hsa-miR-621:PITA hsa-miR-621:PITA_TOP PITA 5.85E-11 3.17E-07 1.57E-10 1.44E-09 14 101 "NLGN4X,ELMOD1,ANK3,CAB39,DNER,GLS,SYT6,DCLK1,PFKFB3,NRXN1,CAMKV,HP1BP3,PTPRD,PAK5" MicroRNA hsa-miR-1279:PITA hsa-miR-1279:PITA_TOP PITA 5.89E-11 3.19E-07 1.58E-10 1.45E-09 20 238 "LGR4,NLGN4X,GPR158,TACC2,CADPS,PALLD,GPR162,GFRA1,BTRC,ANO4,TCF12,REPS2,CADM1,CNTN1,ATRNL1,KCNA1,SMG7,TMEM255A,ABI1,FAM135B" MicroRNA hsa-miR-182*:mirSVR_highEffct hsa-miR-182*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.89E-11 3.19E-07 1.58E-10 1.45E-09 30 548 "ACTN2,ATAT1,ADARB2,KLHL32,SLITRK1,SORCS1,LINC00461,GPAM,ST3GAL3,ATM,EIF4G3,ILDR2,SPART,UNC5D,NPPA,GRIK4,MAEL,LGI1,ZNF384,CADM1,NEGR1,PIK3CD,VAV2,KCNT2,FEZ2,ATRNL1,FGFR1OP2,DTNA,OLIG2,RCAN2" MicroRNA hsa-miR-331-5p:PITA hsa-miR-331-5p:PITA_TOP PITA 6.22E-11 3.37E-07 1.67E-10 1.53E-09 16 142 "EPS8,ASIC1,SYT9,WAC,FOXG1,USP16,ARHGAP5,PHYHIPL,TCF12,PCDH9,PCSK2,PLD5,KIAA0408,ITGAV,JAKMIP2,SRGAP3" MicroRNA hsa-miR-509-3-5p:PITA hsa-miR-509-3-5p:PITA_TOP PITA 6.31E-11 3.42E-07 1.69E-10 1.55E-09 22 294 "CSMD2,SCN3A,ANK1,SH3GL2,NLGN1,ARHGAP5,RCOR3,WDTC1,NCAM1,CAMTA1,AZIN2,CAMK2G,DCLK1,CCSER2,NCAN,CTNND1,MAGI2,KCNA1,PTPRZ1,KCNMA1,SNX27,EPB41" MicroRNA hsa-miR-509-5p:PITA hsa-miR-509-5p:PITA_TOP PITA 6.31E-11 3.42E-07 1.69E-10 1.55E-09 22 294 "CSMD2,SCN3A,ANK1,SH3GL2,NLGN1,ARHGAP5,RCOR3,WDTC1,NCAM1,CAMTA1,AZIN2,CAMK2G,DCLK1,CCSER2,NCAN,CTNND1,MAGI2,KCNA1,PTPRZ1,KCNMA1,SNX27,EPB41" MicroRNA hsa-miR-1203:mirSVR_lowEffct hsa-miR-1203:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.32E-11 3.42E-07 1.70E-10 1.56E-09 24 353 "TTYH1,HOGA1,SOX6,PKP4,CGREF1,NAXD,SLN,WDTC1,TTLL9,SMOC1,AJAP1,ARHGEF7,TMEM25,CELF3,PAX6,ARHGAP19,IGFN1,CHI3L2,CTNND2,LRRTM3,LRP8,FAM57B,RALGDS,USH1C" MicroRNA hsa-miR-150-5p:TargetScan hsa-miR-150-5p TargetScan 6.33E-11 3.43E-07 1.70E-10 1.56E-09 21 266 "RIMKLA,RCSD1,MRVI1,MDM4,ITSN1,PKP4,APC,GPAM,DKK3,SCN3B,NFASC,PTBP2,CAMK2G,CELF3,REPS2,FNDC5,NLGN3,NEGR1,FTO,KCNN3,ABI2" MicroRNA hsa-miR-361-5p:PITA hsa-miR-361-5p:PITA_TOP PITA 6.33E-11 3.43E-07 1.70E-10 1.56E-09 21 266 "LGR4,ADCY2,ADD3,PKP4,PPM1E,MYT1L,GLS,GPM6A,PSD3,PCDH9,MAGI1,PDE4B,KIAA1549L,CTNND1,CTNND2,RIMS3,KCNA1,PLEKHB2,FAM13C,EPB41,RCAN2" MicroRNA hsa-miR-633:PITA hsa-miR-633:PITA_TOP PITA 6.33E-11 3.43E-07 1.70E-10 1.56E-09 21 266 "GALNT13,GPR158,KIAA1109,NLGN1,SHTN1,AQP4,SORCS3,SON,MYT1L,CAB39,CACNA1A,ACSL6,VWC2,CAMK2G,CIART,JAM2,DOCK7,CEP170,PTPRD,ABI1,EPB41L2" MicroRNA hsa-miR-874-3p:TargetScan hsa-miR-874-3p TargetScan 6.35E-11 3.44E-07 1.70E-10 1.56E-09 20 239 "DSCAML1,GRAMD1B,FGF1,MOG,PAAF1,CPLX2,HEPN1,AJAP1,MYRF,CACNA1E,CACNB2,PSD3,PAX6,COL9A2,PRRX1,POU3F2,PSD,PLEKHB2,ATG16L1,ELAVL3" MicroRNA hsa-miR-1184:PITA hsa-miR-1184:PITA_TOP PITA 6.35E-11 3.44E-07 1.70E-10 1.56E-09 20 239 "ARID1A,TOMM40L,SCN3A,ANK1,ARHGAP5,SMARCE1,RCOR3,CAB39,RND1,CAMTA1,CAMK2G,NSD2,FEZ1,NCAN,CTNND1,RIMS3,KCNN3,DLG2,BSDC1,TTLL7" MicroRNA hsa-miR-662:mirSVR_lowEffct hsa-miR-662:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.36E-11 3.44E-07 1.70E-10 1.56E-09 27 448 "MBP,MEG3,MOBP,TRIM46,APBA2,ST3GAL3,SON,IDI2-AS1,ADAM15,KIF1B,CPLX2,C11orf87,COLGALT2,BCL2L2,GNAS,CACNB2,ZDHHC22,TNS1,PIK3CD,BEST1,HES5,NOS1AP,WBP1L,SPIRE1,BDNF-AS,RABGAP1L,KCNMA1" MicroRNA hsa-miR-541:mirSVR_highEffct hsa-miR-541:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-11 3.58E-07 1.77E-10 1.62E-09 28 482 "MAG,ASIC1,RTN3,SLITRK1,TOMM40L,ASIC4,CNIH2,SORBS1,ARFGAP1,SMARCE1,JPH4,SMOC1,RCOR2,PHLDB1,GANAB,SEPT3,NODAL,TCF7L2,GPR17,LINC00839,TMEM257,CAMKV,BEST1,ZNF385B,ELMO1,LRP8,EPB41L2,SEZ6" MicroRNA hsa-miR-4254:mirSVR_highEffct hsa-miR-4254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.63E-11 3.59E-07 1.77E-10 1.63E-09 31 586 "RCSD1,RXRG,SORCS1,MOBP,ZNF365,SLC14A1,SPHKAP,ATP2B2,SON,CADM3,DNER,PCDH11X,DCLK2,GNAS,GRIK3,PAH,PCDH9,LGI1,PFKFB3,CHRM1,SNCAIP,CA10,STMN4,OCIAD1,DPP6,C12orf4,DBX2,CAMK1G,PHC2,SYT15,EN2" MicroRNA hsa-miR-576-3p:PITA hsa-miR-576-3p:PITA_TOP PITA 6.87E-11 3.72E-07 1.83E-10 1.68E-09 19 214 "LGR4,ADD3,SLC8A2,MYT1L,SOX5,NCAM1,BRSK2,GRIA2,TPD52,PIK3CD,PRRX1,NXPH1,PPP3CB,LRP8,SMG7,DLG2,ATG16L1,ZYG11B,INSYN2" MicroRNA hsa-miR-152:PITA hsa-miR-152:PITA_TOP PITA 6.93E-11 3.75E-07 1.85E-10 1.70E-09 28 483 "ASIC1,RTN3,ADCY2,APBB1,MIER1,DNER,NCAM1,NEUROD1,SYT4,GPM6A,CACNB2,CAMK2A,NUMA1,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,CADM1,BEST1,POU3F2,MED1,PTPRD,SNX27,DLG2,RTN4,ST8SIA3,EPB41L1" MicroRNA hsa-miR-148b:PITA hsa-miR-148b:PITA_TOP PITA 6.93E-11 3.75E-07 1.85E-10 1.70E-09 28 483 "ASIC1,RTN3,ADCY2,APBB1,MIER1,DNER,NCAM1,NEUROD1,SYT4,GPM6A,CACNB2,CAMK2A,NUMA1,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,CADM1,BEST1,POU3F2,MED1,PTPRD,SNX27,DLG2,RTN4,ST8SIA3,EPB41L1" MicroRNA hsa-miR-148a:PITA hsa-miR-148a:PITA_TOP PITA 6.93E-11 3.75E-07 1.85E-10 1.70E-09 28 483 "ASIC1,RTN3,ADCY2,APBB1,MIER1,DNER,NCAM1,NEUROD1,SYT4,GPM6A,CACNB2,CAMK2A,NUMA1,TNFRSF1B,RBFOX2,MAGI1,PDE1C,PDE4B,CADM1,BEST1,POU3F2,MED1,PTPRD,SNX27,DLG2,RTN4,ST8SIA3,EPB41L1" MicroRNA hsa-miR-3196:mirSVR_highEffct hsa-miR-3196:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.00E-11 3.79E-07 1.87E-10 1.71E-09 15 122 "SLITRK1,ST3GAL3,LGI3,TNIK,NKX2-2,KAZN,DDR1,INA,FNDC5,DLGAP3,KIAA1549L,CABP1,NSD2,ANKS1B,RFX4" MicroRNA hsa-miR-1277-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.20E-11 3.90E-07 1.92E-10 1.76E-09 32 624 "ACER3,GRAMD1B,NLGN4X,CCDC80,MYBPC1,WDTC1,SOX5,AJAP1,DDHD2,GRID1,GRIK3,CADM1,NEGR1,MEAF6,SLC25A27,BTF3L4,PRRX1,ACBD5,PPP2R5C,MAPK8,PUM1,PROX1,ZBTB16,CADM2,LRP8,KCNK1,KCNN3,RAB5B,L1CAM,SSPN,ABI2,RCAN2" MicroRNA hsa-miR-6731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.52E-11 4.07E-07 2.00E-10 1.84E-09 24 356 "DPF1,PDZD4,SOX6,SFMBT2,CCDC88A,ASPH,WDTC1,ADGRB2,AJAP1,FAM168A,ASTN2,HAP1,TMPRSS5,CHRNB2,FTO,BTF3L4,PACSIN1,RGS6,MICAL2,KIAA0513,PHYHIP,PTPRE,NKAIN1,ELAVL3" MicroRNA hsa-miR-6749-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-11 4.08E-07 2.00E-10 1.84E-09 25 387 "FAM43B,GRAMD1B,SLIT1,SMARCE1,PALLD,CASTOR3,NODAL,CAMK2G,DDR2,GRID1,GRIK3,CDH8,HMGB1,TMPRSS5,TLX1,SLC22A6,TENM4,ZBTB16,PTAFR,PMEPA1,KCNJ4,TMCC2,KCNJ11,RAB5B,FAM13C" MicroRNA hsa-miR-642:PITA hsa-miR-642:PITA_TOP PITA 8.02E-11 4.35E-07 2.13E-10 1.96E-09 17 167 "CSMD3,FGF1,ITSN1,ARFGAP2,CAPRIN2,MEGF11,SOX5,AHCYL1,ERBIN,NCDN,RND1,SEPT3,INA,TNS1,NEGR1,BRINP3,LRRTM3" MicroRNA hsa-miR-660:PITA hsa-miR-660:PITA_TOP PITA 8.02E-11 4.35E-07 2.13E-10 1.96E-09 17 167 "ABAT,SCN3A,SCN4B,UNC79,SFPQ,PKP4,TBX15,OPCML,PCDH9,PCSK2,MAGI1,CADM1,VAV2,TOX,INSYN2,RBM12,CBLN2" MicroRNA "CTGAGCC,MIR-24:MSigDB" "CTGAGCC,MIR-24:MSigDB" MSigDB 8.06E-11 4.37E-07 2.14E-10 1.97E-09 19 216 "WDTC1,KIF21B,ARPP21,BCL2L2,NEUROD1,SEMA4A,HAP1,VXN,ATP13A2,TMEM9,MAGI1,NSD2,PTPRD,SRGAP3,TMCC2,KCNK2,NAV2,RAB5B,SFXN5" MicroRNA hsa-miR-222:PITA hsa-miR-222:PITA_TOP PITA 8.36E-11 4.52E-07 2.22E-10 2.04E-09 21 270 "ARID1A,ADD3,SHTN1,CCDC88A,CAPRIN2,SNCB,SOX10,NAP1L2,CAMTA1,GPM6A,TCF12,NXPH1,MED1,RGS6,RIMS4,MAPK10,TOX,RIMS3,KCNK2,SLC17A6,PAK5" MicroRNA hsa-miR-3199:mirSVR_highEffct hsa-miR-3199:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.37E-11 4.53E-07 2.22E-10 2.04E-09 28 487 "ATAT1,CHST15,TOMM40L,PAAF1,SLC1A7,MSRA,SORCS3,NPAS3,CLASP2,SEPT3,ARHGEF7,HAP1,EML4,MAEL,TPM3,PDE3B,CASC2,CADM1,A2ML1,SF1,FEZ1,FMN2,EDRF1,PROX1,LRP8,SNX27,PIANP,RCAN2" MicroRNA hsa-miR-27b*:mirSVR_highEffct hsa-miR-27b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.46E-11 4.58E-07 2.25E-10 2.06E-09 32 628 "ABAT,PRR5L,SLC30A10,ANK2,USP28,PKP4,GPAM,MIER1,NAXD,SMARCE1,PHYHIPL,USP33,SLCO1C1,CAMSAP2,CNTN2,TCF7L2,NUMA1,GRIA4,TGFBR3,TIE1,UBTF,OPALIN,CELF5,OSBPL3,NRSN1,MAPK10,FGFR1OP2,CEP170,KCNK1,NUP214,FAM135B,RPRD1A" MicroRNA hsa-miR-3200:mirSVR_highEffct hsa-miR-3200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.87E-11 4.80E-07 2.35E-10 2.16E-09 25 390 "SORCS1,SGIP1,ITSN1,ZNF365,SMARCE1,RCOR3,GAD2,KIF1B,RGL1,ADHFE1,PCDH11X,GPR17,CRB1,TJP1,C1orf94,CDH8,CADM1,BTF3L4,PPP3CB,ATRNL1,ITGAV,MAGI2,PCDH15,INSYN2,SLC4A10" MicroRNA hsa-miR-214*:mirSVR_highEffct hsa-miR-214*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.87E-11 4.80E-07 2.35E-10 2.16E-09 25 390 "DPF1,ABAT,TMEM74,EYA1,KLHL32,WAC,SLC30A10,MOBP,MOG,ARFGAP2,RCOR3,TNIK,WSCD1,PTBP2,P2RX7,TNR,TJP2,PKN2,SPIRE1,PRTFDC1,BLOC1S6,KCNN3,L1CAM,RPRD1A,RPE65" MicroRNA hsa-miR-185-5p:Functional MTI Functional MTI miRTarbase 8.93E-11 4.84E-07 2.37E-10 2.17E-09 24 359 "DPF1,ZFYVE27,ARID1A,PDZD4,CACHD1,SFMBT2,PKNOX2,CCDC88A,C10orf105,WDTC1,NEUROD1,TMEM9,CDC42,TMPRSS5,PFKFB3,CADM1,SF1,PTPA,MICAL2,ZC3H11A,SMG7,RAB5B,PLEKHB2,ELAVL3" MicroRNA hsa-miR-424*:mirSVR_highEffct hsa-miR-424*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.17E-11 4.96E-07 2.43E-10 2.23E-09 32 630 "WLS,GALNT13,FOXG1,ASRGL1,GPAM,MSR1,CSPG5,DLL3,CAPRIN2,SMARCE1,NEK6,SPART,C11orf87,STOX1,GLS,GNAS,KLHL4,VSTM2A,TMEM257,MAEL,CDH8,ZMYND8,ZBED5,HNRNPK,NRXN1,PUM1,MASP1,PRDM2,HP1BP3,SMG7,GOPC,SYT15" MicroRNA hsa-miR-4286:mirSVR_highEffct hsa-miR-4286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.88E-11 5.35E-07 2.61E-10 2.40E-09 25 392 "EPS8,WLS,TOMM40L,ITSN1,ARFGAP2,SMARCE1,ATP1A3,GABBR1,KIF1B,RND1,ADGRL3,TBX15,PTBP2,GRID1,MAEL,HEPACAM,NOS1AP,FGFR1OP2,BDNF-AS,KCNC1,KCND3,HS3ST4,DTNA,SEC61A2,RPRD1A" MicroRNA hsa-miR-433:PITA hsa-miR-433:PITA_TOP PITA 9.90E-11 5.36E-07 2.62E-10 2.40E-09 20 245 "CSMD3,CLIP1,SESN3,PCDH11X,CAMTA1,BTRC,EML4,TJP1,MAGI1,NEGR1,NMT2,NXPH1,MED1,PPP3CB,HP1BP3,CEP170,STMN4,KCNMA1,ABI1,RBM12" MicroRNA hsa-miR-378b:mirSVR_highEffct hsa-miR-378b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.95E-11 5.39E-07 2.63E-10 2.41E-09 33 669 "MAP6,KCNIP2,FABP7,SORCS1,SLC44A5,FCGR1A,FOXG1,NSG2,SORCS3,EIF4G3,NCAM1,BCL2L2,NEUROD1,ARHGEF7,GLS,GNAS,CAMTA1,GRIA4,TF,LGI1,HMGB1,KIAA1549L,CAMKV,C11orf49,PLPP4,PTPRD,KIF2A,DSCAM,CAMK1G,ZNF248,RBM12,SH3GLB1,BAALC" MicroRNA hsa-miR-591:PITA hsa-miR-591:PITA_TOP PITA 9.97E-11 5.40E-07 2.64E-10 2.42E-09 14 105 "TESK2,ITSN1,PPM1E,ATP2B2,MEGF11,GANAB,GRM3,TJP1,NEGR1,PPP3CB,MAPK10,KCNK2,PEX5,ARHGAP12" MicroRNA "AAGCACT,MIR-520F:MSigDB" "AAGCACT,MIR-520F:MSigDB" MSigDB 1.02E-10 5.54E-07 2.70E-10 2.48E-09 19 219 "SLITRK3,SLC6A9,ATP2B2,LMO3,RGL1,MYRF,OPCML,ZFP91,PRKACB,TOX,SYNC,RGMA,OLFM3,KCNMA1,RALGDS,FAM13C,PAK5,RFX4,VANGL2" MicroRNA hsa-miR-221:PITA hsa-miR-221:PITA_TOP PITA 1.03E-10 5.55E-07 2.71E-10 2.48E-09 21 273 "ARID1A,ADD3,SHTN1,CCDC88A,CAPRIN2,SNCB,SOX10,NAP1L2,CAMTA1,GPM6A,TCF12,NXPH1,MED1,RGS6,RIMS4,MAPK10,TOX,RIMS3,KCNK2,SLC17A6,PAK5" MicroRNA hsa-miR-142-3p.1:TargetScan hsa-miR-142-3p.1 TargetScan 1.03E-10 5.55E-07 2.71E-10 2.48E-09 21 273 "ANK3,APC,RAP1GAP2,LMO3,GFAP,GNAS,EML4,RBFOX2,PDE4B,HMGB1,ACBD5,CTNND1,PUM1,PROX1,ITGAV,COPS7A,ATG16L1,JMJD1C,RPRD1A,ABI2,ARHGAP12" MicroRNA hsa-miR-346:TargetScan hsa-miR-346 TargetScan 1.05E-10 5.69E-07 2.77E-10 2.54E-09 16 147 "RIMKLA,GOLGA7B,PDZD4,LRRC4C,CADM3,KIF1B,NCDN,AJAP1,NODAL,MMD2,GRIN1,PTPN5,MFSD2A,ECE2,CALN1,EPB41L1" MicroRNA hsa-miR-6129:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-10 5.72E-07 2.79E-10 2.56E-09 22 302 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,SF1,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-661:mirSVR_highEffct hsa-miR-661:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-10 5.73E-07 2.79E-10 2.56E-09 28 492 "KCNIP2,DSCAML1,RXRG,BCAR3,TRIM46,APBA2,APC,BCAN,CAPRIN2,RCOR3,JPH4,NCAM1,GFAP,ZFP91,TNR,CDH8,PDYN,CHRM1,CCDC136,CELF5,COL9A2,SLC36A4,MICAL2,PKN2,KCNJ10,RASGRF1,RNF220,RPRD1A" MicroRNA "CTACTGT,MIR-199A:MSigDB" "CTACTGT,MIR-199A:MSigDB" MSigDB 1.06E-10 5.76E-07 2.80E-10 2.57E-09 17 170 "MAP6,SEMA6C,ANK2,TACC2,LRRC4C,ASCL1,SORCS3,ZNF638,CAMTA1,GPM6A,EML4,BRSK2,PTPN5,CDC42,NXPH1,KCNK1,DLG3" MicroRNA hsa-miR-149:PITA hsa-miR-149:PITA_TOP PITA 1.06E-10 5.76E-07 2.80E-10 2.57E-09 17 170 "CACHD1,SNCB,KIF1B,ADGRB2,BCL2L2,NCDN,PHLDB1,TCF12,FBXL16,ARHGAP19,MED1,SF1,SNCAIP,RIMS4,KCNK2,DLG3,RNF220" MicroRNA hsa-miR-1229:PITA hsa-miR-1229:PITA_TOP PITA 1.14E-10 6.15E-07 2.99E-10 2.74E-09 14 106 "RTN1,PPM1E,APC,ASCL1,ATP2B2,SOX5,ZCCHC24,CADM3,GRIA2,CADM1,CELF5,ITGAV,KCNA1,DLG2" MicroRNA hsa-miR-1909:mirSVR_highEffct hsa-miR-1909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-10 6.15E-07 2.99E-10 2.74E-09 29 528 "CDHR1,FGF1,AMPH,NTNG1,GPAM,ST3GAL3,ARFGAP2,ASPH,WDTC1,JPH4,FXYD6,SEPT3,ABCC8,NKX2-2,TBX15,DDR1,CRB1,PC,LRTM2,MS4A7,HERC2P3,ZFYVE9,SYTL2,TOMM20,JAKMIP2,PLPPR4,KCNC1,PEX5,RAB5B" MicroRNA hsa-miR-28-3p:mirSVR_highEffct hsa-miR-28-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-10 6.31E-07 3.06E-10 2.81E-09 35 749 "SORCS1,ADORA3,ANK2,CACHD1,NLGN1,DACH2,SMARCE1,SNAP25,FYN,PHYHIPL,JPH4,CLASP2,GANAB,LUZP2,GPM6A,GRIA2,LINC00839,ZFP91,CDC42,HMGB1,CASC2,ANLN,VCAN,PUM1,EDRF1,SYTL2,ANKS1B,LRRTM3,PLPPR1,PCDH15,GOPC,DTNA,SEC61A2,SFXN5,ARHGAP12" MicroRNA hsa-miR-146b-5p:PITA hsa-miR-146b-5p:PITA_TOP PITA 1.17E-10 6.32E-07 3.07E-10 2.81E-09 17 171 "MAPT,GPR158,AMPH,SESN3,SCN3B,NPAS3,CLASP2,EML4,GRID1,CELF3,CADM1,MED1,TOX,LRRTM3,CADM2,KCNMA1,TMEM255A" MicroRNA hsa-miR-146a:PITA hsa-miR-146a:PITA_TOP PITA 1.17E-10 6.32E-07 3.07E-10 2.81E-09 17 171 "MAPT,GPR158,AMPH,SESN3,SCN3B,NPAS3,CLASP2,EML4,GRID1,CELF3,CADM1,MED1,TOX,LRRTM3,CADM2,KCNMA1,TMEM255A" MicroRNA hsa-miR-3147:mirSVR_highEffct hsa-miR-3147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-10 6.58E-07 3.19E-10 2.93E-09 28 495 "PRR5L,RCSD1,ATAT1,KLHL32,FABP7,ADORA3,CNIH2,PKP4,BRINP2,SPART,ADHFE1,MMD2,GRIK2,LINC00839,LEFTY2,USP2,INA,P2RX7,MAEL,PDYN,BEST3,PACSIN1,RAB39A,MASP1,HP1BP3,PTPRE,ABI1,SEC61A2" MicroRNA hsa-miR-632:mirSVR_highEffct hsa-miR-632:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-10 6.60E-07 3.20E-10 2.93E-09 34 712 "SERPINA3,SYT9,ARID1A,SORCS1,LRRTM4,ERICH3,ANK2,USP28,SORBS1,LRRC4C,SORCS3,RCOR3,RCOR2,ZNF638,PTPN5,MAGI1,NEGR1,NXPH1,SNCAIP,VCAN,RAB39A,CTNND2,MAPK10,MASP1,CA10,OCIAD1,PTPRE,NTM,FAM66C,SLC6A15,RFX4,RPRD1A,SLC4A10,EPB41L1" MicroRNA hsa-miR-650:PITA hsa-miR-650:PITA_TOP PITA 1.24E-10 6.74E-07 3.26E-10 2.99E-09 18 196 "SDE2,ASIC1,WDTC1,KIF21B,JPH4,GPR162,NCDN,NRGN,CAMK2G,CELF3,CCSER2,RIMS4,CTNND1,KCNA1,RAB5B,PAK5,RGS7,PIANP" MicroRNA hsa-miR-624:PITA hsa-miR-624:PITA_TOP PITA 1.26E-10 6.80E-07 3.29E-10 3.02E-09 21 276 "TESK2,SFPQ,ITSN1,SORBS1,FYN,MEGF11,MYT1L,CPLX2,SPART,ADGRL3,CACNA1A,NEGR1,PRRX1,TENM4,RBPJ,PUM1,PMEPA1,TMEM255A,ST8SIA3,JMJD1C,VANGL2" MicroRNA hsa-miR-1207-3p:PITA hsa-miR-1207-3p:PITA_TOP PITA 1.26E-10 6.80E-07 3.29E-10 3.02E-09 21 276 "MAPT,SCN3A,NTNG1,MEGF11,GANAB,UNC5D,GRIA4,TPM3,NRXN2,FAT3,CHD5,RIMS3,COPS7A,RGMA,DLG3,TMEM255A,L1CAM,BSDC1,INSYN2,RBM12,EPB41L1" MicroRNA hsa-miR-4306:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-10 7.16E-07 3.46E-10 3.18E-09 20 249 "DPF1,ZFYVE27,ARID1A,PDZD4,SFMBT2,PKNOX2,CCDC88A,C10orf105,WDTC1,NEUROD1,TMEM9,TMPRSS5,PFKFB3,CADM1,SF1,PTPA,MICAL2,ZC3H11A,RAB5B,ELAVL3" MicroRNA hsa-miR-10a-5p:Functional MTI Functional MTI miRTarbase 1.33E-10 7.17E-07 3.46E-10 3.18E-09 27 463 "ADGRV1,ERMN,FOXRED2,SFPQ,API5,URGCP,MTR,IGSF9B,ATP1A2,SON,LHFPL4,FAM168A,BTRC,ARHGAP19,TPM4,CADM1,UBTF,MEAF6,MED1,IGSF1,CTNND1,MAPK8,PSMD13,CAB39L,PLEKHB2,RPRD1A,EPB41L2" MicroRNA hsa-miR-1274b:mirSVR_highEffct hsa-miR-1274b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-10 7.17E-07 3.46E-10 3.18E-09 27 463 "ATAT1,CSMD2,KLHL32,GRAMD1B,LRRTM4,SGIP1,NTNG1,NEK6,GART,NPAS3,SPART,NEUROD1,SEZ6L,ZNF384,CASC2,HNRNPK,MED1,MICAL2,HP1BP3,CEP170,PTPRD,KCNJ9,DSCAM,RFX4,FAM135B,RPRD1A,GPR61" MicroRNA hsa-miR-1306:mirSVR_lowEffct hsa-miR-1306:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-10 7.17E-07 3.46E-10 3.18E-09 27 463 "EPS8,SERPINA3,LGR4,ADCY2,DSCAML1,TRIM46,NTNG1,MADD,FYN,NEUROD1,POPDC3,CNTN2,CYB561A3,OPCML,TNFRSF1B,ARHGAP19,HNRNPK,FEZ2,ZNF385B,OCIAD1,SRGAP3,TMCC2,KCNK2,DLG3,RALGDS,USH1C,EPB41L2" MicroRNA hsa-miR-425*:mirSVR_lowEffct hsa-miR-425*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-10 7.21E-07 3.48E-10 3.19E-09 28 497 "RTN3,ADGRV1,LCNL1,APC,MAGI3,MT3,SCG3,SPHKAP,NELL1,NRGN,AZIN2,PCDHGA3,GRIA2,MFSD2A,HEPACAM,PLXNB3,NSD2,FEZ1,PRKAB2,NOS1AP,DNAJC6,CSDE1,KCNA1,NAV2,DLG2,OLIG1,FAM135B,CACNG7" MicroRNA hsa-miR-186-5p:Functional MTI Functional MTI miRTarbase 1.34E-10 7.27E-07 3.51E-10 3.22E-09 35 753 "TTYH1,SDE2,ACER3,RBM10,WLS,FOXRED2,FOXM1,APC,CCDC80,SON,NASP,TGFBR3,P2RX7,ZFP91,RBFOX2,BTF3L4,SF1,RIMS4,RBPJ,PRKAB2,PLPP4,PUM1,RIMS3,DPYSL5,SPIRE1,TUBB2B,PSMD13,BDNF-AS,CSDE1,BLOC1S6,DLG3,RALGDS,BEND5,PAK5,RGR" MicroRNA hsa-miR-146b-3p:mirSVR_highEffct hsa-miR-146b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-10 7.52E-07 3.63E-10 3.33E-09 27 464 "LDLRAD3,SGIP1,ANXA7,SESN3,NTNG1,DGKD,PAAF1,ZNF365,SON,TTLL9,ADHFE1,ADGRL3,CAMK2G,DDR2,GRIK2,TF,PLEKHB1,CASC2,TMEFF2,ETNPPL,SNCAIP,NRSN1,COPS7A,KCNJ9,NAV2,PAK5,RFX4" MicroRNA hsa-miR-1976:mirSVR_highEffct hsa-miR-1976:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-10 7.55E-07 3.64E-10 3.34E-09 31 604 "SYT9,ECSIT,ARID1A,MDM4,F3,TMEM156,SNX32,LINC00461,MTR,RCOR3,ZSWIM8,TTLL9,LUZP2,ROBO3,TCF7L2,AIFM1,CDH8,ZMYND8,FLRT1,CCDC136,PRRX1,MED1,FEZ1,PHACTR3,RBPJ,PLPPR5,PSMD13,SV2A,DLG2,CAMK1G,RFX4" MicroRNA hsa-miR-27a*:mirSVR_highEffct hsa-miR-27a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-10 7.59E-07 3.66E-10 3.36E-09 26 431 "TMEM74,FOXG1,ITSN1,ANXA7,BCAS1,SLC8A3,SLIT1,DLL3,ATM,SOX1,KIF21B,DCAF5,HEPN1,SEPT3,NFIA,KLHL4,LINC00839,MED1,CSF3R,MASP1,HP1BP3,COPS7A,CEP170,SNX27,L1CAM,RPRD1A" MicroRNA "GAGCTGG,MIR-337:MSigDB" "GAGCTGG,MIR-337:MSigDB" MSigDB 1.43E-10 7.72E-07 3.72E-10 3.41E-09 16 150 "SEMA6A,DGKZ,SLC1A2,NFASC,VAMP1,CAMK2G,PSD3,OPCML,ACOT7,CAMKV,IFFO1,NSD2,FAM131B,SNX27,DSCAM,ROM1" MicroRNA hsa-miR-4292:mirSVR_highEffct hsa-miR-4292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-10 7.75E-07 3.73E-10 3.42E-09 25 399 "EPS8,SYT9,EYA1,FGF1,PKP4,TACC2,LRRC55,CCDC88A,SOX5,TBX15,DAAM2,MAEL,SEZ6L,CIART,SEMA5B,POU3F2,PPP2R5C,SNCAIP,PPP3CB,NCAN,PLPP4,MAPK10,PTPRE,RABGAP1L,RAP1GAP" MicroRNA hsa-miR-1300:PITA hsa-miR-1300:PITA_TOP PITA 1.43E-10 7.77E-07 3.74E-10 3.43E-09 21 278 "GPR158,LRRC7,NLGN1,API5,CADPS,RND1,CAMTA1,GPM6A,TCF12,EML4,TMEM257,MAGI1,CADM1,CAMKV,PLD5,CTNND2,SYNC,PTCH1,SMG7,WIPF2,SIDT2" MicroRNA hsa-miR-215-5p:Functional MTI Functional MTI miRTarbase 1.44E-10 7.80E-07 3.75E-10 3.44E-09 35 755 "EPS8,RIMKLA,CNTNAP3,MDM4,CDC7,ASRGL1,PKP4,APC,CLSTN1,SCMH1,ASPH,EMC1,PSRC1,GPR19,PTBP2,VXN,ARHGAP19,TPM4,ANLN,TJP2,NSD2,FAAP20,PNKD,USP54,EDRF1,ZNF385B,ITGAV,LRP8,COPS7A,BLOC1S6,PTPRE,RAP1GAP,RET,ZNF248,EEF1A2" MicroRNA hsa-miR-122*:mirSVR_highEffct hsa-miR-122*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-10 8.16E-07 3.92E-10 3.60E-09 19 224 "SYT9,BCO1,SNAP25,TNIK,CAB39,NELL1,PCDH11X,LUZP2,NUDT21,GRIA2,GPR88,HMGB1,CHD1L,MED1,NTM,KCNK2,TMEM255A,SLC6A15,LMO1" MicroRNA hsa-miR-508-5p:mirSVR_highEffct hsa-miR-508-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-10 8.18E-07 3.93E-10 3.61E-09 33 680 "ACER3,SLC25A25,CSMD3,KLHL32,KIAA1109,ELMOD1,APBB1,MIER1,GAD2,SEPT3,FAM168A,GLS,KLHL4,GRIA2,GRIA4,CRB1,MFSD2A,AIFM1,HPS5,TPD52,PDE4B,BEST3,PLXNB3,SLC36A4,CNRIP1,TMCC2,C12orf4,RGS7,EFNA3,RPRD1A,ARHGAP12,SLC4A10,BAALC" MicroRNA hsa-miR-29c:mirSVR_highEffct hsa-miR-29c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.51E-10 8.19E-07 3.93E-10 3.61E-09 43 1082 "MAP6,RBM10,RTN3,CDC7,GRAMD1B,BCAR3,SFPQ,APC,GPAM,BCAS1,CAPRIN2,ASPH,BRINP2,DKK3,ARPP21,KIF1B,ADGRB2,NAP1L2,NPAS3,NASP,NCAM1,DDHD2,MMD2,PTBP2,EML4,VSTM2A,HRH3,FNDC5,MS4A7,HNRNPK,CCSER2,POU3F2,CRMP1,PRKAB2,IGSF1,DPYSL5,PLPPR5,LRRTM3,DNAJC6,PTHLH,SV2A,NAV2,SH3GLB1" MicroRNA hsa-miR-125a-3p:PITA hsa-miR-125a-3p:PITA_TOP PITA 1.54E-10 8.32E-07 3.99E-10 3.66E-09 17 174 "ADD3,NLGN1,FYN,MEGF11,MYT1L,LMO3,GANAB,GNG3,PCDH8,CCSER2,BEST1,BTF3L4,RIMS4,CADM2,HP1BP3,KCNA1,KIF2A" MicroRNA hsa-miR-651-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-10 8.80E-07 4.22E-10 3.87E-09 19 225 "SYT9,AMER2,SOX6,SESN3,CCDC80,LGI3,CAB39,NCAM1,SEPT3,EML4,RBFOX2,TPM4,BTF3L4,SF1,CTNND1,PUM1,CSDE1,ZYG11B,SEZ6" MicroRNA "CACCAGC,MIR-138:MSigDB" "CACCAGC,MIR-138:MSigDB" MSigDB 1.73E-10 9.39E-07 4.50E-10 4.13E-09 18 200 "ANK1,ST3GAL3,SNCB,CASTOR3,UNC5D,ADGRL3,CACNA1E,TPM4,PCSK2,MEAF6,OSBPL3,RIMS3,NTM,KCNMA1,CALN1,DSCAM,JMJD1C,RCAN2" MicroRNA hsa-miR-1:PITA hsa-miR-1:PITA_TOP PITA 1.75E-10 9.45E-07 4.53E-10 4.15E-09 24 371 "SLC25A25,ADAR,FGF14,ASRGL1,API5,SLC8A2,SNAP25,SOX5,CPLX2,NEUROD1,ANO4,TGFBR3,TPM3,HNRNPK,GDAP1L1,MED1,WBP1L,ELMO1,SMG7,KIF2A,WIPF2,RGS7,EPB41L1,RCAN2" MicroRNA hsa-miR-206:PITA hsa-miR-206:PITA_TOP PITA 1.75E-10 9.45E-07 4.53E-10 4.15E-09 24 371 "SLC25A25,ADAR,FGF14,ASRGL1,API5,SLC8A2,SNAP25,SOX5,CPLX2,NEUROD1,ANO4,TGFBR3,TPM3,HNRNPK,GDAP1L1,MED1,WBP1L,ELMO1,SMG7,KIF2A,WIPF2,RGS7,EPB41L1,RCAN2" MicroRNA hsa-miR-613:PITA hsa-miR-613:PITA_TOP PITA 1.84E-10 9.98E-07 4.78E-10 4.38E-09 24 372 "SLC25A25,ADAR,FGF14,ASRGL1,API5,SLC8A2,SNAP25,SOX5,CPLX2,NEUROD1,ANO4,TGFBR3,TPM3,HNRNPK,GDAP1L1,MED1,WBP1L,ELMO1,SMG7,KIF2A,WIPF2,RGS7,EPB41L1,RCAN2" MicroRNA hsa-miR-1321:PITA hsa-miR-1321:PITA_TOP PITA 1.88E-10 1.02E-06 4.88E-10 4.47E-09 18 201 "ASIC1,RTKN,CADM3,JPH4,RND1,CAMK2G,GRIK2,OMG,TPM3,NRXN2,PRRX1,MED1,MICAL2,PTPRO,SNX27,DLG3,GPR61,ELAVL3" MicroRNA hsa-miR-1291:PITA hsa-miR-1291:PITA_TOP PITA 1.95E-10 1.06E-06 5.05E-10 4.63E-09 15 131 "LGR4,SGIP1,MAGI3,CADM3,DCAF5,HAP1,SYT6,GRIN1,RBFOX2,CAMKV,MED1,PHYHIP,PTPRD,KCNN3,VANGL2" MicroRNA hsa-miR-1288:mirSVR_highEffct hsa-miR-1288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.95E-10 1.06E-06 5.05E-10 4.63E-09 23 342 "CNTNAP3,CHST15,MOBP,SORBS1,PAAF1,SLC2A5,SLC8A2,CADPS,MEGF11,NPAS3,NEUROD1,ANO4,GRIK2,CRLS1,ATRNL1,VCAN,CTNND1,NOS1AP,PROX1,ITGAV,ELMO1,DTNA,PAK5" MicroRNA hsa-miR-376a-3p:TargetScan hsa-miR-376a-3p TargetScan 2.04E-10 1.11E-06 5.28E-10 4.84E-09 18 202 "DSCAML1,AMER2,ANK2,CLASP2,DCAF5,GRIK2,GRIK3,AIFM1,PAX6,MED1,PRKACB,HES5,FAM131B,JAKMIP2,PTHLH,COPS7A,ABI2,EN2" MicroRNA hsa-miR-376b-3p:TargetScan hsa-miR-376b-3p TargetScan 2.04E-10 1.11E-06 5.28E-10 4.84E-09 18 202 "DSCAML1,AMER2,ANK2,CLASP2,DCAF5,GRIK2,GRIK3,AIFM1,PAX6,MED1,PRKACB,HES5,FAM131B,JAKMIP2,PTHLH,COPS7A,ABI2,EN2" MicroRNA hsa-miR-1539:mirSVR_lowEffct hsa-miR-1539:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-10 1.11E-06 5.31E-10 4.87E-09 24 374 "MDM4,WAC,CDC7,CDC42BPA,ANK1,SLC8A3,ARFGAP1,WDTC1,ADAM15,GFAP,ZNF638,GNAS,DDR1,NTSR2,HMGB1,SEMA5B,CNRIP1,MICAL2,PRKAB2,PRKCG,NTM,KCNK1,NUP214,SYT15" MicroRNA hsa-miR-766:PITA hsa-miR-766:PITA_TOP PITA 2.12E-10 1.15E-06 5.47E-10 5.02E-09 16 154 "SDE2,ASIC1,SLC1A2,CADM3,NCDN,VAMP1,HAP1,GRIA2,RBFOX2,TPM3,PPP3CB,OSBPL3,RIMS4,PRKCG,CADM2,DLG2" MicroRNA hsa-miR-147:PITA hsa-miR-147:PITA_TOP PITA 2.12E-10 1.15E-06 5.47E-10 5.02E-09 16 154 "SLITRK1,NLGN4X,ANK1,ANK3,SLC1A2,TMEM151A,AHCYL1,NCAM1,RND1,NFIA,CAMTA1,CACNA1A,CADM1,CABP1,SMG7,L1CAM" MicroRNA hsa-miR-496.2:TargetScan hsa-miR-496.2 TargetScan 2.17E-10 1.18E-06 5.61E-10 5.15E-09 15 132 "ERMN,ITSN1,MIER1,ATP2B2,LMO3,GFRA1,GPR26,GRID1,GRIK2,DAAM2,REPS2,PFKFB3,LRRTM3,EPB41L1,EPB41L2" MicroRNA hsa-miR-3680-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.20E-10 1.19E-06 5.66E-10 5.20E-09 17 178 "ACER3,ARID1A,WAC,SEMA6A,SLC30A10,SESN3,LRRC55,UNC5D,HMGB1,UBTF,COL9A2,VCAN,RBPJ,MAPK8,KIAA0408,MED24,ST8SIA3" MicroRNA hsa-miR-221-3p:TargetScan hsa-miR-221-3p TargetScan 2.29E-10 1.24E-06 5.90E-10 5.41E-09 24 376 "ARID1A,MDM4,FGF14,RPH3A,CCDC88A,CAPRIN2,ASPH,MYT1L,NAP1L2,C11orf87,AJAP1,ARHGEF7,GPM6A,PTBP2,MAGI1,NXPH1,MED1,OSBPL3,RIMS4,PLD5,MAPK10,RIMS3,KCNK2,DLG2" MicroRNA hsa-miR-222-3p:TargetScan hsa-miR-222-3p TargetScan 2.29E-10 1.24E-06 5.90E-10 5.41E-09 24 376 "ARID1A,MDM4,FGF14,RPH3A,CCDC88A,CAPRIN2,ASPH,MYT1L,NAP1L2,C11orf87,AJAP1,ARHGEF7,GPM6A,PTBP2,MAGI1,NXPH1,MED1,OSBPL3,RIMS4,PLD5,MAPK10,RIMS3,KCNK2,DLG2" MicroRNA hsa-miR-4278:mirSVR_highEffct hsa-miR-4278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-10 1.28E-06 6.07E-10 5.57E-09 22 315 "LINC00461,DISP3,MOBP,USP28,LMO3,NDUFA5,NELL1,RGL1,RND1,SYT4,GRIA1,DCLK1,SLC25A27,BEST1,SF1,KCNT2,RBPJ,USP54,SYNC,PRDM2,RLBP1,ABI2" MicroRNA hsa-miR-3144-5p:mirSVR_highEffct hsa-miR-3144-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-10 1.28E-06 6.07E-10 5.57E-09 22 315 "AMER2,SCN3A,MOBP,ITSN1,PKP4,BCAS1,SLC1A7,CAPRIN2,MTR,GABBR1,LMO3,STOX1,HEPN1,UNC5D,CNDP1,B4GALNT4,NRGN,CAMK2G,GUCY1A2,MAEL,MAGI1,FNDC5" MicroRNA hsa-miR-614:mirSVR_lowEffct hsa-miR-614:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-10 1.30E-06 6.18E-10 5.67E-09 25 409 "ZFYVE27,SYT9,DRAXIN,ST3GAL3,BCL2L2,ALDH1L1,CASTOR3,PCDH11X,CNTN2,EML4,GRIA2,INA,TLL2,MAEL,TPD52,ZMYND8,OPALIN,MICAL2,KIAA0513,PTAFR,COPS7A,RALGDS,NUP214,INSYN2,ABI2" MicroRNA hsa-miR-802:TargetScan hsa-miR-802 TargetScan 2.42E-10 1.31E-06 6.21E-10 5.70E-09 21 286 "ABAT,ARID1A,APC,MEGF11,CAB39,NMNAT2,GUCY1A2,DCLK1,RBFOX2,KIAA1549L,NEGR1,NMT2,LRRTM3,PTCH1,CA10,JAKMIP2,CSDE1,GOPC,DSCAM,JMJD1C,ABI2" MicroRNA hsa-miR-3194:mirSVR_highEffct hsa-miR-3194:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.55E-10 1.38E-06 6.55E-10 6.01E-09 24 378 "ZFYVE27,MEG3,CSMD3,ITSN1,GPAM,SYBU,SORCS3,SON,CAB39,KIF1B,RGL1,CASTOR3,ANO4,AZIN2,RFFL,ZDHHC22,ZFP91,DUSP26,SEMA5B,MEAF6,BEST1,PRKAB2,SLC25A48,DTNA" MicroRNA hsa-miR-200a*:mirSVR_highEffct hsa-miR-200a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-10 1.39E-06 6.58E-10 6.04E-09 37 851 "TMEM74,WLS,MOBP,SHTN1,RUFY2,MSR1,ARFGAP2,NSG2,SLC14A1,SPHKAP,SMARCE1,ENKUR,ARPP21,KIF1B,NPAS3,GLS,DDHD2,PRUNE2,GRIA4,TMEM257,C1orf94,LGI1,HMGB1,ZBED5,BTF3L4,NSD2,CRLS1,KCNT2,RBPJ,NRSN1,EDRF1,ANKS1B,LRRTM3,KLRC2,DPP6,ABCC9,VWA5A" MicroRNA hsa-miR-28-5p:PITA hsa-miR-28-5p:PITA_TOP PITA 2.57E-10 1.39E-06 6.60E-10 6.05E-09 16 156 "PDZD4,AMPH,ANK1,IGSF9B,NCAM1,GPM6A,GRIA4,DCLK1,HNRNPK,PRDM2,SNX27,WIPF2,DPP6,JMJD1C,SH3GLB1,EN2" MicroRNA hsa-miR-29a:mirSVR_highEffct hsa-miR-29a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.58E-10 1.40E-06 6.62E-10 6.07E-09 41 1016 "MAP6,RBM10,RTN3,ADD3,CDC7,GRAMD1B,BCAR3,SFPQ,APC,GPAM,CAPRIN2,ASPH,BRINP2,DKK3,ARPP21,KIF1B,ADGRB2,NPAS3,NASP,NCAM1,MMD2,PTBP2,EML4,VSTM2A,HRH3,FNDC5,MS4A7,HNRNPK,CCSER2,MED1,CRMP1,PRKAB2,IGSF1,DPYSL5,PLPPR5,LRRTM3,DNAJC6,PTHLH,SV2A,NAV2,SH3GLB1" MicroRNA hsa-miR-449c*:mirSVR_highEffct hsa-miR-449c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-10 1.40E-06 6.65E-10 6.10E-09 30 583 "MOG,NLGN1,SMARCE1,RCOR3,PALLD,SOX5,KIF1B,ADHFE1,SEPT3,ZNF638,CAMTA1,ADGRL3,ZEB1,PTBP2,ADAMTS8,TLL2,ZFP91,CDH8,TPM4,PDE1C,CASC2,HEPACAM,NXPH1,MFSD4A,FEZ1,OLFM3,KIF2A,DNAH9,ABI1,DTNA" MicroRNA hsa-miR-24-2*:mirSVR_highEffct hsa-miR-24-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-10 1.40E-06 6.65E-10 6.10E-09 23 347 "SYT9,CDC7,DRAXIN,HOGA1,MOBP,SGIP1,ASPH,ENKUR,ARPP21,ERBIN,GLS,TCF7L2,TCF12,GRIA4,OLR1,USP2,PCDH9,NXPH1,IGSF1,NRSN1,TOMM20,MAGI2,KCNK2" MicroRNA hsa-miR-199a-5p:PITA hsa-miR-199a-5p:PITA_TOP PITA 2.66E-10 1.44E-06 6.81E-10 6.25E-09 20 259 "ZFYVE27,CLIP1,ADD3,SCN3A,KIAA1109,SEMA6A,ANK3,NTNG1,SORCS3,KIF1B,GANAB,RND1,CAMSAP2,ANO4,CADM1,PIK3CD,RGMA,MAGI2,TMEM255A,ARHGAP12" MicroRNA hsa-miR-199b-5p:PITA hsa-miR-199b-5p:PITA_TOP PITA 2.66E-10 1.44E-06 6.81E-10 6.25E-09 20 259 "ZFYVE27,CLIP1,ADD3,SCN3A,KIAA1109,SEMA6A,ANK3,NTNG1,SORCS3,KIF1B,GANAB,RND1,CAMSAP2,ANO4,CADM1,PIK3CD,RGMA,MAGI2,TMEM255A,ARHGAP12" MicroRNA hsa-miR-4264:mirSVR_highEffct hsa-miR-4264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.70E-10 1.46E-06 6.91E-10 6.34E-09 29 548 "CSMD3,MOG,SGIP1,ITSN1,CACHD1,SHTN1,MIER1,MSR1,SPHKAP,SLN,DKK3,TNIK,ACSL6,GRM3,TJP1,CNTN1,ACBD5,NRSN1,PRDM2,ZC3H11A,SMG7,KCNK2,KIF2A,GOPC,BSDC1,SLC6A15,FAM135B,YY1AP1,OLIG2" MicroRNA hsa-miR-941:mirSVR_lowEffct hsa-miR-941:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-10 1.48E-06 7.02E-10 6.44E-09 31 621 "IL17D,ASIC4,MOG,APBA2,SORBS1,MADD,CAPRIN2,MTR,ADAM15,PCDH11X,GNG4,FAM69C,HAP1,PTBP2,AKNA,GRIA1,ATP13A2,AIFM1,PCSK2,LINC01102,NRXN2,FTO,NOS1AP,HP1BP3,LRP8,DNM2,FAM57B,DPP6,NUP214,PHC2,RLBP1" MicroRNA hsa-miR-1915:mirSVR_highEffct hsa-miR-1915:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-10 1.51E-06 7.13E-10 6.54E-09 26 445 "PRR5L,RCSD1,SYNDIG1,TOMM40L,SNX32,FOXG1,ITSN1,SLITRK3,ZNF365,CADPS,ARPP21,VAMP1,WSCD1,DDR1,TCF12,VXN,DAAM2,IGFN1,FNDC5,CNTN1,OSBPL3,SYNC,DLG2,DNM2,RFX5,YY1AP1" MicroRNA hsa-miR-652:mirSVR_lowEffct hsa-miR-652:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.82E-10 1.53E-06 7.22E-10 6.62E-09 22 318 "ITSN1,PKP4,ST3GAL3,KIAA1614,RPH3A,SLIT1,RCOR3,KIF21B,ADGRB2,FXYD6,GNAS,TCF12,LINC00839,PRRX1,FAAP20,PRKCZ,KCNJ11,PLEKHB2,FAM66C,ATG16L1,SEC61A2,SEZ6" MicroRNA hsa-miR-3115:mirSVR_highEffct hsa-miR-3115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.96E-10 1.60E-06 7.58E-10 6.95E-09 31 623 "SNX30,SCN4B,LRRTM4,LRRC7,FGF14,SLC30A10,USP28,APBA2,ST3GAL3,CCDC88A,RCOR3,CAB39,AHCYL1,TTLL9,KIF1B,SPART,NCAM1,C11orf87,GPR17,TMEM25,HPS5,PDE1C,PRMT8,CASC2,NEGR1,CELF5,KIAA0408,LRRTM3,AK5,RFX5,ZNF248" MicroRNA hsa-miR-608:PITA hsa-miR-608:PITA_TOP PITA 2.99E-10 1.62E-06 7.65E-10 7.02E-09 15 135 "ASIC1,CNIH2,YPEL4,SNAP25,PALLD,CADM3,NPAS3,GANAB,VAMP1,DLGAP3,CABP1,PSD,TMEM255A,RTN4,ELAVL3" MicroRNA hsa-miR-1825:mirSVR_highEffct hsa-miR-1825:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-10 1.66E-06 7.85E-10 7.20E-09 27 481 "ACHE,RTN3,GPR158,LRRTM4,NTNG1,ASPH,SORCS3,ATP1A2,ENKUR,NCAM1,ERBIN,TMEM136,CACNB2,CECR2,GRIA4,GPR88,PDE1C,NLGN3,BTF3L4,PKN2,MAPK10,PLPPR5,DLG2,DTNA,RTN4,PHC2,GPR61" MicroRNA hsa-miR-363*:mirSVR_highEffct hsa-miR-363*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-10 1.67E-06 7.86E-10 7.22E-09 31 624 "LDLRAD3,MDM4,SLITRK1,SEMA6A,ANK3,SLITRK3,AQP4,ZNF365,MIER1,SORCS3,ALDH4A1,NELL1,PSRC1,ANO4,BRSK2,AKNA,OLR1,CRB1,CDC42,TPM3,ZNF384,ST8SIA5,COL9A2,SYTL2,ELMO1,DTNA,INSYN2,SYT15,RBM12,VWA5A,PRRT4" MicroRNA hsa-let-7i*:mirSVR_lowEffct hsa-let-7i*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-10 1.69E-06 7.95E-10 7.29E-09 21 290 "MEG3,LINC00461,SLITRK3,ST3GAL3,PKNOX2,ARHGEF7,NKX2-2,CRB1,CDH10,DCLK1,ARHGAP19,PRRX1,RBPJ,TOX,DPYSL5,PTHLH,OLIG1,BSDC1,ZYG11B,SEC61A2,EPB41L2" MicroRNA hsa-miR-554:mirSVR_highEffct hsa-miR-554:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.24E-10 1.76E-06 8.27E-10 7.59E-09 23 351 "RCSD1,TOMM40L,GPR158,CDC42BPA,NLGN1,LRRC55,CCDC88A,DACH2,SMARCE1,RCOR3,PALLD,TTLL9,RND1,UNC5D,CACNB2,ADAMTS8,BTF3L4,FEZ1,RBPJ,CTNND1,MAGI2,RALGDS,ABI1" MicroRNA hsa-miR-1301:PITA hsa-miR-1301:PITA_TOP PITA 3.25E-10 1.76E-06 8.30E-10 7.61E-09 20 262 "ARID1A,WAC,TOMM40L,TESK2,RASA3,RCOR3,B3GAT1,MEGF11,ZCCHC24,CLASP2,CAMTA1,CECR2,NCAN,PHACTR3,PMEPA1,MAGI2,SMG7,SNX27,DLG2,DLG3" MicroRNA hsa-miR-3165:mirSVR_highEffct hsa-miR-3165:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.36E-10 1.82E-06 8.57E-10 7.86E-09 27 483 "SYT9,ADGRV1,KCNIP2,ITSN1,CACHD1,PKNOX2,SLC8A3,CGREF1,SOX5,NASP,NELL1,PSRC1,GPM6B,INA,RBFOX2,SPATA6,POU3F2,PNKD,VCAN,USP54,TOMM20,NTM,KCNMA1,PARP11,RFX5,INSYN2,SLC4A10" MicroRNA hsa-miR-603:PITA hsa-miR-603:PITA_TOP PITA 3.69E-10 2.00E-06 9.39E-10 8.62E-09 24 385 "LGR4,LDLRAD3,NTNG1,NLGN1,SLC8A2,DACH2,LHFPL4,DNER,NCAM1,COLGALT2,ERBIN,DCAF5,BTRC,TBX15,TCF12,GRIA1,FMN2,CTNND1,PMEPA1,KCNA2,PTPRD,SMG7,KCNK2,TMEM255A" MicroRNA hsa-miR-383:PITA hsa-miR-383:PITA_TOP PITA 3.69E-10 2.00E-06 9.39E-10 8.62E-09 15 137 "GALNT13,SORCS1,SOX6,SLC1A2,CSPG5,SOX5,NCAM1,NEUROD1,GLS,NRGN,DCLK1,FNDC5,NXPH1,BLOC1S6,PTPRE" MicroRNA hsa-miR-18b*:mirSVR_highEffct hsa-miR-18b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.83E-10 2.07E-06 9.74E-10 8.94E-09 23 354 "ACTN2,SLIT1,ATM,MEGF11,USP33,ENKUR,NFASC,LILRA1,PTBP2,NUMA1,GRIA1,GRIA2,GRIA4,GRIN1,A2ML1,PRRX1,OSBPL3,PRKACB,SYTL2,BDNF-AS,DLG2,ARHGEF10L,ARHGAP12" MicroRNA hsa-miR-4297:mirSVR_highEffct hsa-miR-4297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.88E-10 2.10E-06 9.86E-10 9.04E-09 30 593 "PPFIA1,AQP4,SMARCE1,GABBR1,LMO3,CASTOR3,ADGRL3,CAMK2G,GRIA2,GRIA4,GRIN1,INA,TPM3,CADM1,PIK3CD,PMP2,POU3F2,SF1,RBPJ,DZIP3,CTNND2,ANKS1B,SPIRE1,DNAJC6,SMG7,PTPRE,RABGAP1L,HS3ST4,GNE,SEC61A2" MicroRNA hsa-miR-593*:mirSVR_highEffct hsa-miR-593*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.88E-10 2.10E-06 9.87E-10 9.05E-09 31 630 "TMEM74,SYT9,GALNT13,BCAS1,RUFY2,ARFGAP2,RCOR3,KIF1B,ADGRB2,NPAS3,CLASP2,ADHFE1,CAMTA1,MMD2,GRIA4,PAH,PDE4B,PDYN,HNRNPK,FTO,BTF3L4,FMN2,NOS1AP,SIRPA,HP1BP3,NTM,KCNN3,DTNA,PIANP,RPRD1A,LPAR6" MicroRNA hsa-miR-421:PITA hsa-miR-421:PITA_TOP PITA 4.05E-10 2.19E-06 1.03E-09 9.43E-09 23 355 "ABAT,EYA1,TESK2,ELMOD1,SOX6,PPM1E,ARHGAP5,SLC8A2,SNAP25,NCAM1,CAMTA1,CAMSAP2,FBXL16,DAAM2,PDE4B,SERPINE2,NXPH1,POU3F4,SF1,JAKMIP2,CADM2,ARHGAP12,RCAN2" MicroRNA hsa-miR-599:PITA hsa-miR-599:PITA_TOP PITA 4.09E-10 2.22E-06 1.04E-09 9.53E-09 15 138 "SORCS1,GPR158,LRRC4C,CLASP2,SEPT3,NFIA,UNC5D,TCF12,PDE4B,RBPJ,CEP170,PTPRD,SNX27,BSDC1,JMJD1C" MicroRNA hsa-miR-193a-3p:TargetScan hsa-miR-193a-3p TargetScan 4.16E-10 2.25E-06 1.05E-09 9.67E-09 18 211 "LGR4,ANK3,CLSTN1,BCL2L2,RGL1,DDR1,CECR2,RFFL,DAAM2,ARHGAP19,CADM1,KIAA1549L,BEST1,PPP2R5C,MAPK10,FAM131B,ABI2,EN2" MicroRNA hsa-miR-193b-3p:TargetScan hsa-miR-193b-3p TargetScan 4.16E-10 2.25E-06 1.05E-09 9.67E-09 18 211 "LGR4,ANK3,CLSTN1,BCL2L2,RGL1,DDR1,CECR2,RFFL,DAAM2,ARHGAP19,CADM1,KIAA1549L,BEST1,PPP2R5C,MAPK10,FAM131B,ABI2,EN2" MicroRNA hsa-miR-8085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.27E-10 2.31E-06 1.08E-09 9.94E-09 23 356 "DPF1,PDZD4,SOX6,SFMBT2,CCDC88A,ASPH,WDTC1,ADGRB2,AJAP1,FAM168A,ASTN2,HAP1,TMPRSS5,CHRNB2,FTO,BTF3L4,RGS6,MICAL2,KIAA0513,PHYHIP,PTPRE,NKAIN1,ELAVL3" MicroRNA hsa-miR-193a-5p:mirSVR_highEffct hsa-miR-193a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.40E-10 2.38E-06 1.11E-09 1.02E-08 28 524 "SYT9,RCSD1,MDM4,ADCY2,DSCAML1,LINC00461,ITSN1,DKK3,GANAB,CASTOR3,PCDH11X,ZNF638,ANO4,GPM6B,DCLK1,ZNF384,PDE1C,PRMT8,CAMKV,POU3F2,PHACTR3,PROX1,MASP1,LRRTM3,OLFM3,FAM13C,USH1C,SLC4A10" MicroRNA hsa-miR-518c:mirSVR_lowEffct hsa-miR-518c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.40E-10 2.38E-06 1.12E-09 1.02E-08 32 671 "MAP6,EXTL1,ACTN2,WLS,PLEKHG5,FOXRED2,SCN3A,LRRC7,MOBP,SLITRK3,BCAN,SHANK2,MEGF11,SON,MYT1L,GFAP,ADHFE1,ZEB1,NRGN,BRSK2,GRIA1,LINC00839,TPM3,BEST3,NRXN1,SULT4A1,SLC25A27,TOX,SIRPA,PTHLH,SRGAP3,BSCL2" MicroRNA hsa-miR-323b-5p:mirSVR_highEffct hsa-miR-323b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.47E-10 2.42E-06 1.13E-09 1.04E-08 26 455 "MAP6,SYT9,PPFIA1,ITSN1,NLGN1,CCDC88A,SCMH1,EIF4G3,NPAS3,CLASP2,GNAS,ZEB1,TCF12,PTBP2,GRIK2,AIFM1,CDC42,SEZ6L,TPM4,FMN2,SPIRE1,CEP170,PTPRE,PCDH15,KCNMA1,ARHGAP12" MicroRNA hsa-miR-762:mirSVR_highEffct hsa-miR-762:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-10 2.47E-06 1.16E-09 1.06E-08 32 672 "NDRG2,CNIH2,PKP4,SON,SOX10,AHCYL1,NFASC,ADHFE1,VAMP1,UNC5D,PRLHR,PTBP2,CECR2,TF,PAH,ZMYND8,HPSE2,PLEKHB1,TLX1,CSF3R,PKN2,PUM1,WBP1L,ZNF385B,LRRTM3,PTPRD,SMG7,RASGRF1,CAMK1G,EFNA3,YY1AP1,EPB41L2" MicroRNA hsa-miR-649:PITA hsa-miR-649:PITA_TOP PITA 4.84E-10 2.62E-06 1.23E-09 1.12E-08 18 213 "ACER3,SOX6,PPM1E,SORBS1,CCDC88A,CAMSAP2,CAMK2G,CECR2,GRIA1,GRIK2,TMEM257,CADM1,KIAA1549L,FAT3,CHD5,RNF220,ELAVL3,EPB41L2" MicroRNA hsa-miR-517b:mirSVR_highEffct hsa-miR-517b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.94E-10 2.68E-06 1.25E-09 1.15E-08 16 163 "SNX32,ERICH3,SLCO1A2,SMARCE1,NEUROD1,TBX15,GRIK2,CASC2,NRXN1,FAM181B,PPP2R5C,LRRTM3,DNAJC6,PTHLH,OLFM3,PTPRD" MicroRNA hsa-miR-938:PITA hsa-miR-938:PITA_TOP PITA 4.95E-10 2.68E-06 1.25E-09 1.15E-08 13 98 "NTNG1,SHTN1,AHCYL1,GPM6A,NUMA1,RFFL,FNDC5,PNKD,TOMM20,KIF2A,VANGL2,ELAVL3,TMEM100" MicroRNA hsa-miR-1277:mirSVR_lowEffct hsa-miR-1277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.14E-10 2.78E-06 1.30E-09 1.19E-08 26 458 "LGR4,RTN3,ARID1A,SORCS1,SOX6,SFPQ,ARHGAP5,SLC8A3,NASP,CASTOR3,NUDT21,CRB1,PTPN5,DAAM2,LINC01102,ANLN,SULT4A1,P2RY12,POU3F2,CRLS1,PPP3CB,SYNC,PTAFR,COPS7A,ATG16L1,ARHGAP12" MicroRNA hsa-miR-1911*:mirSVR_highEffct hsa-miR-1911*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.14E-10 2.78E-06 1.30E-09 1.19E-08 26 458 "MAG,MDM4,TMEM156,TOMM40L,TRIM46,GPAM,TNIK,ERBIN,PHLDB1,KLHL4,CACNB2,GRIK2,CD81,FNDC5,HMGB1,PLEKHB1,A2ML1,BTBD17,ATRNL1,PRTFDC1,CSDE1,KCNJ11,DTNA,ZYG11B,PHC2,TTLL7" MicroRNA hsa-miR-557:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-10 2.79E-06 1.30E-09 1.19E-08 17 188 "ACER3,ARID1A,WAC,SEMA6A,SLC30A10,SESN3,LRRC55,EMC1,UNC5D,HMGB1,UBTF,COL9A2,VCAN,RBPJ,MAPK8,KIAA0408,ST8SIA3" MicroRNA hsa-miR-507:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-10 2.79E-06 1.30E-09 1.19E-08 17 188 "ACER3,ARID1A,WAC,SEMA6A,SLC30A10,SESN3,LRRC55,EMC1,UNC5D,HMGB1,UBTF,COL9A2,VCAN,RBPJ,MAPK8,KIAA0408,ST8SIA3" MicroRNA hsa-miR-1237:PITA hsa-miR-1237:PITA_TOP PITA 5.22E-10 2.83E-06 1.32E-09 1.21E-08 18 214 "BCAR3,AMPH,APBB1,ASTN1,EIF4G3,ZCCHC24,GFRA1,PHLDB1,GRIK2,TNS1,TENM4,KIAA0513,KCNA1,PTPRD,SMG7,PAK5,ARHGAP12,RAVER2" MicroRNA hsa-miR-3130-5p:mirSVR_highEffct hsa-miR-3130-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.44E-10 2.94E-06 1.37E-09 1.26E-08 28 529 "ACER3,ASIC1,CSMD3,SLITRK3,SORCS3,SMARCE1,USP33,GAD2,DCLK2,GPM6B,CRB1,TMEM257,TPD52,HPSE2,CCSER2,NSD2,PRKACB,PRKCZ,ZNF385B,SIRPA,PTCH1,KCNA2,KCNJ11,CAMK1G,RGS7,ATL1,VANGL2,VWA5A" MicroRNA hsa-miR-320c:TargetScan hsa-miR-320c TargetScan 5.52E-10 2.99E-06 1.39E-09 1.27E-08 30 602 "RIMKLA,FOXM1,CCDC80,JAKMIP3,MIER1,ILDR2,DNER,LMO3,NCDN,NFIA,MYRF,CACNA1E,RFFL,GPR88,P2RX7,PDE3B,CHGA,PFKFB3,NEGR1,OSBPL3,RIMS4,PRKAB2,CDH20,KCND3,KCNK1,DLG2,CALN1,DTNA,FAM135B,GPR61" MicroRNA hsa-miR-320b:TargetScan hsa-miR-320b TargetScan 5.52E-10 2.99E-06 1.39E-09 1.27E-08 30 602 "RIMKLA,FOXM1,CCDC80,JAKMIP3,MIER1,ILDR2,DNER,LMO3,NCDN,NFIA,MYRF,CACNA1E,RFFL,GPR88,P2RX7,PDE3B,CHGA,PFKFB3,NEGR1,OSBPL3,RIMS4,PRKAB2,CDH20,KCND3,KCNK1,DLG2,CALN1,DTNA,FAM135B,GPR61" MicroRNA hsa-miR-320d:TargetScan hsa-miR-320d TargetScan 5.52E-10 2.99E-06 1.39E-09 1.27E-08 30 602 "RIMKLA,FOXM1,CCDC80,JAKMIP3,MIER1,ILDR2,DNER,LMO3,NCDN,NFIA,MYRF,CACNA1E,RFFL,GPR88,P2RX7,PDE3B,CHGA,PFKFB3,NEGR1,OSBPL3,RIMS4,PRKAB2,CDH20,KCND3,KCNK1,DLG2,CALN1,DTNA,FAM135B,GPR61" MicroRNA hsa-miR-320a:TargetScan hsa-miR-320a TargetScan 5.52E-10 2.99E-06 1.39E-09 1.27E-08 30 602 "RIMKLA,FOXM1,CCDC80,JAKMIP3,MIER1,ILDR2,DNER,LMO3,NCDN,NFIA,MYRF,CACNA1E,RFFL,GPR88,P2RX7,PDE3B,CHGA,PFKFB3,NEGR1,OSBPL3,RIMS4,PRKAB2,CDH20,KCND3,KCNK1,DLG2,CALN1,DTNA,FAM135B,GPR61" MicroRNA hsa-miR-326:PITA hsa-miR-326:PITA_TOP PITA 5.59E-10 3.03E-06 1.41E-09 1.29E-08 17 189 "SDE2,SYT9,KCNIP2,ITSN1,MAGI3,ARFGAP2,SLC8A2,SNCB,ATP2B2,BCL2L2,ERBIN,CELF3,PPP3CB,RIMS4,PRKAB2,KIAA0513,BSDC1" MicroRNA hsa-miR-330-5p:PITA hsa-miR-330-5p:PITA_TOP PITA 5.59E-10 3.03E-06 1.41E-09 1.29E-08 17 189 "SDE2,SYT9,KCNIP2,ITSN1,MAGI3,ARFGAP2,SLC8A2,SNCB,ATP2B2,BCL2L2,ERBIN,CELF3,PPP3CB,RIMS4,PRKAB2,KIAA0513,BSDC1" MicroRNA hsa-miR-425:mirSVR_highEffct hsa-miR-425:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.64E-10 3.06E-06 1.42E-09 1.30E-08 37 876 "SYT9,SORCS1,GRAMD1B,ELMOD1,AMPH,SGIP1,ANK3,PPM1E,BCAS1,API5,MSR1,SLC8A3,ASPH,SNAP25,CAB39,NDUFA5,NELL1,AJAP1,GLS,LRIT2,NPPA,TNS1,LGI1,TJP2,CRLS1,KCNT2,PHACTR3,PRKCZ,USP54,PTCH1,BDNF-AS,PEX5,PARP11,FAM135B,FGFBP3,SLC4A10,BAALC" MicroRNA hsa-miR-107:Functional MTI Functional MTI miRTarbase 5.77E-10 3.12E-06 1.45E-09 1.33E-08 21 300 "MDM4,CLIP1,ADORA3,SEMA6A,SH3GL2,SMARCE1,MYBPC1,CAB39,GANAB,NFIA,EML4,TGFBR3,TJP1,CDC42,CHGA,CHRM1,PPP2R5C,VCAN,RIMS3,COPS7A,EN2" MicroRNA "GTGCCAT,MIR-183:MSigDB" "GTGCCAT,MIR-183:MSigDB" MSigDB 5.92E-10 3.21E-06 1.49E-09 1.36E-08 16 165 "SLITRK1,SOX6,PKP4,PPM1E,SLITRK3,ARFGAP2,SNCB,LMO3,TCF12,EML4,KCNK10,TPM3,TUB,PPP2R5C,KCNK2,RALGDS" MicroRNA "GGGACCA,MIR-133A:MSigDB" "GGGACCA,MIR-133A:MSigDB" MSigDB 6.07E-10 3.29E-06 1.52E-09 1.40E-08 17 190 "SLC25A25,FOXG1,SLC8A3,NFASC,BCL2L2,GANAB,CDK5R2,PTBP2,PCDHGA3,NUMA1,ZFP91,CDC42,PFKFB3,SEMA5B,PRRX1,PACSIN1,DNM2" MicroRNA "GGGACCA,MIR-133B:MSigDB" "GGGACCA,MIR-133B:MSigDB" MSigDB 6.07E-10 3.29E-06 1.52E-09 1.40E-08 17 190 "SLC25A25,FOXG1,SLC8A3,NFASC,BCL2L2,GANAB,CDK5R2,PTBP2,PCDHGA3,NUMA1,ZFP91,CDC42,PFKFB3,SEMA5B,PRRX1,PACSIN1,DNM2" MicroRNA hsa-miR-552:PITA hsa-miR-552:PITA_TOP PITA 6.07E-10 3.29E-06 1.52E-09 1.40E-08 17 190 "MRVI1,NLGN1,API5,SLC8A3,GANAB,CAMTA1,ATF7,OPCML,DLGAP3,BTF3L4,PACSIN1,POU3F2,MAPK10,HP1BP3,ZC3H11A,WIPF2,RAB5B" MicroRNA hsa-miR-6130:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-10 3.32E-06 1.54E-09 1.41E-08 21 301 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-4419a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-10 3.32E-06 1.54E-09 1.41E-08 21 301 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-567:PITA hsa-miR-567:PITA_TOP PITA 6.47E-10 3.51E-06 1.62E-09 1.49E-08 16 166 "ACLY,ARID1A,CLIP1,CCDC88A,EIF4G3,B3GALT2,NEUROD1,CDC42,USP54,CTNND2,PUM1,SYNC,CADM2,KCNMA1,DLG2,EPB41L2" MicroRNA "AATGTGA,MIR-23B:MSigDB" "AATGTGA,MIR-23B:MSigDB" MSigDB 6.48E-10 3.51E-06 1.62E-09 1.49E-08 24 396 "LGR4,EYA1,PKP4,SHANK2,PALLD,B3GALT2,CAB39,NEK6,SEPT3,GLS,CAMTA1,ANO4,NRGN,TGFBR3,TPM3,MAGI1,PDE4B,NRXN1,NSD2,TOX,DNAJC6,SRGAP3,SNX27,DLG2" MicroRNA "AATGTGA,MIR-23A:MSigDB" "AATGTGA,MIR-23A:MSigDB" MSigDB 6.48E-10 3.51E-06 1.62E-09 1.49E-08 24 396 "LGR4,EYA1,PKP4,SHANK2,PALLD,B3GALT2,CAB39,NEK6,SEPT3,GLS,CAMTA1,ANO4,NRGN,TGFBR3,TPM3,MAGI1,PDE4B,NRXN1,NSD2,TOX,DNAJC6,SRGAP3,SNX27,DLG2" MicroRNA hsa-miR-339-5p:TargetScan hsa-miR-339-5p TargetScan 6.76E-10 3.66E-06 1.69E-09 1.55E-08 15 143 "LDLRAD3,FHL1,PDZD4,KIF1B,NFASC,PRUNE2,HAP1,DAAM2,PFKFB3,HNRNPK,NRXN1,MED1,JAKMIP2,KCND3,DLG3" MicroRNA hsa-miR-491-5p:TargetScan hsa-miR-491-5p TargetScan 6.76E-10 3.66E-06 1.69E-09 1.55E-08 15 143 "CSMD2,GRAMD1B,MOG,KIAA1614,MYT1L,NFASC,BCL2L2,HAP1,CELF3,PADI2,DLGAP3,FADS2,EFNA3,ELAVL3,ELAVL4" MicroRNA hsa-miR-4510:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.91E-10 3.74E-06 1.73E-09 1.58E-08 21 303 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-3135:mirSVR_highEffct hsa-miR-3135:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.13E-10 3.86E-06 1.78E-09 1.63E-08 20 274 "SYT9,DUSP27,ADD3,NLGN4X,AMPH,DKK3,SLCO1C1,DDHD2,CAMTA1,UNC5D,TMEM136,TCF7L2,ZEB1,GRID1,CADM1,FLRT1,PNKD,GON4L,HP1BP3,PIANP" MicroRNA hsa-miR-2276-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.13E-10 3.86E-06 1.78E-09 1.63E-08 17 192 "ASIC4,DKK3,INKA2,ZNF638,NODAL,TMEM151B,GRID1,OLR1,ZDHHC22,CDH8,PRMT8,GPR37L1,PNKD,RGS6,KCNJ9,ST8SIA3,VANGL2" MicroRNA hsa-miR-4316:mirSVR_highEffct hsa-miR-4316:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.43E-10 4.03E-06 1.85E-09 1.70E-08 25 432 "EYA1,MRVI1,SORBS1,ATM,DKK3,SON,NPAS3,NELL1,ANO4,PRUNE2,GRIK3,CYB561A3,TIE1,CAMKV,SNCAIP,MICAL2,RBPJ,PLPP4,NRSN1,DKFZp779M0652,LRP8,RABGAP1L,KCNJ10,CAMK1G,FGFBP3" MicroRNA hsa-miR-770-5p:mirSVR_highEffct hsa-miR-770-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.75E-10 4.20E-06 1.93E-09 1.77E-08 26 467 "ADGRV1,ATAT1,RYR1,ANK3,MAGI3,ST3GAL3,AQP4,SMARCE1,EIF4G3,DNER,GRIA1,GRIA2,PRMT8,NXPH1,PPP2R5C,NRSN1,KCNA2,TMCC2,KCNK1,SLC17A6,ABI1,DTNA,BSDC1,ABCC9,ARHGAP12,RCAN2" MicroRNA hsa-miR-6133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-10 4.21E-06 1.94E-09 1.78E-08 21 305 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-6127:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-10 4.21E-06 1.94E-09 1.78E-08 21 305 "DPF1,MAG,CLSTN1,RPH3A,CCDC88A,NDUFA5,SMOC1,GFRA1,ASTN2,DDR1,HAP1,TPM3,TMPRSS5,PTPA,KIAA0513,NAV2,NKAIN1,RAB5B,PARP11,EN2,EPB41L1" MicroRNA hsa-miR-939:mirSVR_highEffct hsa-miR-939:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.79E-10 4.22E-06 1.94E-09 1.78E-08 27 502 "MRVI1,KCNIP2,CLIP1,ADORA3,ASIC4,PKP4,ST3GAL3,MTR,FYN,DKK3,JPH4,ARPP21,TTLL9,BCL2L2,CYB561A3,USP2,ZFP91,PADI2,PIRT,CHRM1,PLEKHB1,PLPPR1,KLRC2,CAMK1G,SEC61A2,PIANP,VWA5A" MicroRNA hsa-miR-21-5p:Functional MTI Functional MTI miRTarbase 7.81E-10 4.23E-06 1.94E-09 1.78E-08 30 611 "MDM4,SNX30,TESK2,ASRGL1,DOCK10,APC,GPAM,PALLD,SOX5,NFIA,DDHD2,DDR2,RFFL,OLR1,TGFBR3,HPS5,HMGB1,CASC2,HNRNPK,CADM1,NSD2,ACBD5,OSBPL3,PRKAB2,DOCK7,EDRF1,GNE,RTN4,ZYG11B,ELAVL4" MicroRNA hsa-miR-337-5p:mirSVR_lowEffct hsa-miR-337-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.12E-10 4.40E-06 2.02E-09 1.85E-08 23 368 "CLIP1,TOMM40L,AGT,GOLGA7B,CDC42BPA,ITSN1,AQP4,ENKUR,NEK6,NPAS3,GLS,CAMTA1,MMD2,GRIA4,PDE1C,CNRIP1,MED1,SNCAIP,VCAN,RBPJ,EDRF1,COPS7A,YY1AP1" MicroRNA "CCTGCTG,MIR-214:MSigDB" "CCTGCTG,MIR-214:MSigDB" MSigDB 8.16E-10 4.42E-06 2.03E-09 1.86E-08 18 220 "MAPT,ACLY,SORCS1,MOBP,MOG,DGKZ,WDTC1,ARPP21,RAP1GAP2,CAMTA1,GRIN1,FNDC5,RIMS4,RIMS3,RGMA,SRGAP3,PHC2,PIANP" MicroRNA hsa-miR-6511a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.49E-10 4.60E-06 2.11E-09 1.94E-08 27 504 "SDE2,PLEKHG5,PNMA8B,SLC30A10,MAGI3,CCDC80,DNAH17,ATM,TMEM151A,SCN3B,KIF1B,ACSBG1,GNG4,CAMSAP2,DDR1,NUCB1,RBFOX2,TPM3,SCRG1,DLGAP3,UBTF,CCSER2,RBPJ,DPYSL5,SNX27,RAB5B,PLEKHB2" MicroRNA hsa-miR-196b-5p:TargetScan hsa-miR-196b-5p TargetScan 8.62E-10 4.67E-06 2.14E-09 1.96E-08 20 277 "FGF14,GAS7,AQP4,SALL3,RAP1GAP2,AJAP1,PRUNE2,ACSL6,OPCML,PFKFB3,NRXN1,FLRT1,RBPJ,MAPK8,LRRTM3,HP1BP3,BLOC1S6,ABI2,RAVER2,ELAVL4" MicroRNA hsa-miR-196a-5p:TargetScan hsa-miR-196a-5p TargetScan 8.62E-10 4.67E-06 2.14E-09 1.96E-08 20 277 "FGF14,GAS7,AQP4,SALL3,RAP1GAP2,AJAP1,PRUNE2,ACSL6,OPCML,PFKFB3,NRXN1,FLRT1,RBPJ,MAPK8,LRRTM3,HP1BP3,BLOC1S6,ABI2,RAVER2,ELAVL4" MicroRNA hsa-let-7d*:mirSVR_highEffct hsa-let-7d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.06E-10 4.91E-06 2.25E-09 2.06E-08 17 195 "CDC7,API5,NRG3,PHYHIPL,GLS,UNC5D,TCF7L2,GPR88,SCRG1,KCNT2,PRKACB,PLPPR5,PTPRD,RAD52,PARP11,RASGRF1,ABI2" MicroRNA hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 9.18E-10 4.97E-06 2.28E-09 2.09E-08 24 403 "NLGN4X,APBA2,APBB1,SESN3,YPEL4,USP33,GFRA1,INKA2,TCF7L2,EML4,CCKBR,HMGB1,PLPP4,IGSF1,PROX1,CA10,RGMA,CDH20,KCNQ2,DLG2,CALN1,SLC25A18,RTN4,EPB41" MicroRNA hsa-miR-654-5p:mirSVR_highEffct hsa-miR-654-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.28E-10 5.02E-06 2.30E-09 2.11E-08 26 471 "MAG,ASIC1,RTN3,SLITRK1,TOMM40L,ASIC4,CNIH2,ARFGAP1,SMARCE1,JPH4,SMOC1,RCOR2,PHLDB1,SEPT3,NODAL,TCF7L2,GPR17,LINC00839,TMEM257,CAMKV,BEST1,ZNF385B,ELMO1,LRP8,EFNA3,SEZ6" MicroRNA hsa-miR-302c-3p:Functional MTI Functional MTI miRTarbase 9.65E-10 5.23E-06 2.39E-09 2.19E-08 27 507 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CAMK2A,CECR2,DDR2,PSD3,MFSD2A,PTGDR2,TPD52,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,WIPF2,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-1207-5p:PITA hsa-miR-1207-5p:PITA_TOP PITA 1.00E-09 5.43E-06 2.48E-09 2.28E-08 16 171 "HPCAL4,YPEL4,SORCS3,CPLX2,NCDN,VAMP1,ASTN2,ATF7,NRGN,PLEKHB1,TUB,DLGAP3,ACBD5,MED1,PNKD,VANGL2" MicroRNA hsa-miR-26a:PITA hsa-miR-26a:PITA_TOP PITA 1.01E-09 5.49E-06 2.51E-09 2.30E-08 26 473 "RTN1,AMPH,SFPQ,NLGN1,SHTN1,ATP1A2,ZCCHC24,NEK6,CLASP2,VAMP1,PSD3,GRIA4,PCDH9,PDE4B,PFKFB3,ACBD5,PPP2R5C,PPP3CB,CTNND2,JAKMIP2,PTPRD,SLC17A6,SLC6A15,ST8SIA3,VANGL2,RBM12" MicroRNA hsa-miR-26b:PITA hsa-miR-26b:PITA_TOP PITA 1.01E-09 5.49E-06 2.51E-09 2.30E-08 26 473 "RTN1,AMPH,SFPQ,NLGN1,SHTN1,ATP1A2,ZCCHC24,NEK6,CLASP2,VAMP1,PSD3,GRIA4,PCDH9,PDE4B,PFKFB3,ACBD5,PPP2R5C,PPP3CB,CTNND2,JAKMIP2,PTPRD,SLC17A6,SLC6A15,ST8SIA3,VANGL2,RBM12" MicroRNA hsa-miR-1297:PITA hsa-miR-1297:PITA_TOP PITA 1.01E-09 5.49E-06 2.51E-09 2.30E-08 26 473 "RTN1,AMPH,SFPQ,NLGN1,SHTN1,ATP1A2,ZCCHC24,NEK6,CLASP2,VAMP1,PSD3,GRIA4,PCDH9,PDE4B,PFKFB3,ACBD5,PPP2R5C,PPP3CB,CTNND2,JAKMIP2,PTPRD,SLC17A6,SLC6A15,ST8SIA3,VANGL2,RBM12" MicroRNA hsa-miR-1185:PITA hsa-miR-1185:PITA_TOP PITA 1.05E-09 5.68E-06 2.60E-09 2.38E-08 13 104 "KCNIP2,FGF14,FOXM1,SH3GL2,FXYD6,CLASP2,TCF12,TUB,TENM4,CEP170,MAGI2,TMCC2,EFNA3" MicroRNA hsa-let-7e:PITA hsa-let-7e:PITA_TOP PITA 1.05E-09 5.70E-06 2.60E-09 2.39E-08 23 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,ZCCHC24,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-miR-376c-3p:TargetScan hsa-miR-376c-3p TargetScan 1.06E-09 5.74E-06 2.62E-09 2.40E-08 17 197 "GRAMD1B,AMER2,CNIH2,NTNG1,PDE8B,IGSF9B,RAP1GAP2,CACNB2,PTBP2,RFFL,OPCML,HNRNPK,PROX1,RIMS3,PTPRD,RAVER2,EN2" MicroRNA hsa-miR-1178:PITA hsa-miR-1178:PITA_TOP PITA 1.09E-09 5.92E-06 2.70E-09 2.48E-08 16 172 "SYT9,MOBP,TACC2,API5,SON,NFIA,GLS,GPM6A,NUDT21,TPM3,POU3F2,MED1,PPP3CB,PMEPA1,MAGI2,PAK5" MicroRNA hsa-miR-602:PITA hsa-miR-602:PITA_TOP PITA 1.11E-09 6.02E-06 2.74E-09 2.52E-08 9 38 "ARID1A,WAC,FOXG1,NELL1,SYT6,KIAA1549L,TENM4,DPP6,RASGRP2" MicroRNA hsa-miR-876-5p:PITA hsa-miR-876-5p:PITA_TOP PITA 1.15E-09 6.21E-06 2.83E-09 2.59E-08 17 198 "RIMKLA,ASIC1,SLITRK1,WAC,SEMA6A,MAGI3,B3GAT1,SOX5,GPM6A,NEGR1,MED1,SNCAIP,MAGI2,PTPRD,KCNMA1,KCNN3,ELAVL3" MicroRNA hsa-miR-643:PITA hsa-miR-643:PITA_TOP PITA 1.17E-09 6.34E-06 2.89E-09 2.65E-08 18 225 "WAC,NLGN4X,GPR158,SCN3A,BCAR3,ANK3,GAS7,API5,TCF12,GRID1,OPCML,HMGB1,NEGR1,PHACTR3,TOX,SYNC,ABI1,SH3GLB1" MicroRNA "TAGCTTT,MIR-9:MSigDB" "TAGCTTT,MIR-9:MSigDB" MSigDB 1.17E-09 6.34E-06 2.89E-09 2.65E-08 18 225 "RIMKLA,WAC,SORCS1,SLITRK3,ARHGAP5,SORCS3,ERBIN,GPM6A,CAMK2G,TLL2,TPD52,MAGI1,NEGR1,CCSER2,POU3F2,CTNND2,ZNF385B,DNAJC6" MicroRNA hsa-miR-374a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.37E-06 2.90E-09 2.66E-08 20 282 "RPL38,ADD3,GPR158,SESN3,CCDC80,ATM,MYBPC1,LUZP2,CAMSAP2,ZNF384,PDE4B,SLC25A27,FAT3,PMEPA1,LRP8,RAB5B,KLRC3,RALGDS,L1CAM,JMJD1C" MicroRNA hsa-miR-3130-3p:mirSVR_highEffct hsa-miR-3130-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-09 6.42E-06 2.92E-09 2.68E-08 25 442 "ACER3,TMEM74,LRRC7,RASA3,USP28,ITSN1,B3GALT2,ARPP21,C11orf87,CAMSAP2,TCF7L2,LEFTY2,INA,TNR,BTF3L4,NECAB2,TENM4,ECE2,LRRTM3,CA10,CSDE1,PLPPR4,NTM,KCNK2,KCNMA1" MicroRNA hsa-miR-6876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-09 6.71E-06 3.05E-09 2.80E-08 17 199 "MAG,SDE2,ZFYVE27,F3,SMARCE1,ALDH4A1,FAM168A,TMPRSS5,UBTF,PACSIN1,IFFO1,PTPA,KCNJ10,NAV2,RAB5B,PHC2,EN2" MicroRNA hsa-miR-4476:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-09 6.71E-06 3.05E-09 2.80E-08 17 199 "MAG,SDE2,ZFYVE27,F3,SMARCE1,ALDH4A1,FAM168A,TMPRSS5,UBTF,PACSIN1,IFFO1,PTPA,KCNJ10,NAV2,RAB5B,PHC2,EN2" MicroRNA hsa-miR-1205:PITA hsa-miR-1205:PITA_TOP PITA 1.26E-09 6.81E-06 3.09E-09 2.84E-08 18 226 "ASIC1,AMPH,SH3GL2,WDTC1,MYT1L,NMNAT2,ASTN2,CACNA1A,HAP1,AZIN2,CAMK2G,ADAMTS8,TPM3,CCSER2,SMG7,SRGAP3,KCNMA1,CALN1" MicroRNA hsa-miR-668:PITA hsa-miR-668:PITA_TOP PITA 1.27E-09 6.85E-06 3.11E-09 2.85E-08 12 86 "MAPT,CLASP2,NCDN,CACNA1A,CAMK2G,PCDH9,TPD52,PDE3B,NEGR1,POU3F2,MED1,EPB41" MicroRNA hsa-miR-320e:mirSVR_highEffct hsa-miR-320e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.28E-09 6.93E-06 3.15E-09 2.89E-08 32 701 "RTKN,SLITRK1,SORCS1,SLC44A5,AGT,LRRTM4,PKP4,PAAF1,SLC14A1,SORCS3,NRG3,SON,ARHGEF7,CACNA1E,GRIA4,ARHGAP19,TPM4,HERC2P3,GDAP1L1,TJP2,PRRX1,CNRIP1,MFSD4A,KCNT2,ANKS1B,CA10,OCIAD1,RABGAP1L,KCNK2,PEX5,USH1C,RFX4" MicroRNA hsa-miR-1228*:mirSVR_lowEffct hsa-miR-1228*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-09 7.02E-06 3.18E-09 2.92E-08 27 514 "ACHE,KLHL32,HOGA1,FGF1,C1orf61,TRIM46,ANK3,NTNG1,DGKZ,JAKMIP3,URGCP,SLC6A9,MT3,LGI3,ATM,FYN,SOX10,ZSWIM8,ANO4,NEU4,USP2,ASIC3,BEST1,SNCAIP,RTN4,CACNG7,YY1AP1" MicroRNA hsa-miR-574-5p:PITA hsa-miR-574-5p:PITA_TOP PITA 1.33E-09 7.22E-06 3.27E-09 3.00E-08 13 106 "ERICH3,ANK1,SNAP25,AHCYL1,ADGRB2,NCAM1,ANO4,PTBP2,SEMA5B,NEGR1,NSD2,CTNND2,PIANP" MicroRNA "AGGAAGC,MIR-516-3P:MSigDB" "AGGAAGC,MIR-516-3P:MSigDB" MSigDB 1.33E-09 7.22E-06 3.27E-09 3.00E-08 13 106 "ASIC1,SLITRK1,SORCS1,SLITRK3,NCAM1,HEPN1,GPM6B,TCF12,TNR,POU3F4,FAM131B,ZNF385B,EN2" MicroRNA hsa-miR-657:PITA hsa-miR-657:PITA_TOP PITA 1.41E-09 7.62E-06 3.45E-09 3.17E-08 16 175 "MAPT,RTN3,SCN3A,ITSN1,MYT1L,DCLK2,CAMTA1,MAGI1,NRXN1,MED1,TOX,SRGAP3,SNX27,WIPF2,PID1,CALN1" MicroRNA hsa-miR-647:PITA hsa-miR-647:PITA_TOP PITA 1.41E-09 7.62E-06 3.45E-09 3.17E-08 16 175 "ARID1A,ASCL1,CADM3,TBX15,CAMK2G,GRIA2,DCLK1,HPCA,CADM1,PRRX1,MED1,WBP1L,CA10,INSYN2,PHC2,PIANP" MicroRNA "GTGCAAA,MIR-507:MSigDB" "GTGCAAA,MIR-507:MSigDB" MSigDB 1.44E-09 7.79E-06 3.52E-09 3.23E-08 14 128 "SORCS1,SCN3A,UNC79,ATP2B2,NEUROD1,NKX2-2,ADGRL3,ANO4,GRIK2,PAX6,PCDH9,MEAF6,FMN2,DLG3" MicroRNA hsa-miR-485-5p:TargetScan hsa-miR-485-5p TargetScan 1.47E-09 7.96E-06 3.60E-09 3.30E-08 21 316 "ADCYAP1R1,LRRC7,CDC42BPA,NMNAT2,AJAP1,CAMK2A,GRIN1,CELF3,KCNK10,KIAA1549L,MED1,NKAIN4,ATRNL1,SDC3,ECE2,PTAFR,CADM2,LRP8,KCNJ11,PARP11,JMJD1C" MicroRNA hsa-miR-18a-5p:TargetScan hsa-miR-18a-5p TargetScan 1.55E-09 8.40E-06 3.80E-09 3.48E-08 18 229 "RIMKLA,F3,ADD3,FGF1,ANK3,JAKMIP3,CCDC88A,ATM,GNAS,PSD3,DAAM2,CDC42,PRKACB,CADM2,KCNA1,KCNA2,KCND3,EPB41L1" MicroRNA hsa-miR-18b-5p:TargetScan hsa-miR-18b-5p TargetScan 1.55E-09 8.40E-06 3.80E-09 3.48E-08 18 229 "RIMKLA,F3,ADD3,FGF1,ANK3,JAKMIP3,CCDC88A,ATM,GNAS,PSD3,DAAM2,CDC42,PRKACB,CADM2,KCNA1,KCNA2,KCND3,EPB41L1" MicroRNA hsa-miR-455-3p.1:TargetScan hsa-miR-455-3p.1 TargetScan 1.59E-09 8.62E-06 3.90E-09 3.57E-08 20 287 "NTNG1,ARFGAP2,B3GAT1,BCL2L2,GRIK2,GRIK3,MFSD2A,PAX6,PDE3B,FNDC5,NRXN1,RBPJ,PRKAB2,RIMS3,CSDE1,KCNJ4,DLG3,RTN4,PHC2,CBLN2" MicroRNA hsa-miR-4323:mirSVR_highEffct hsa-miR-4323:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-09 8.88E-06 4.01E-09 3.68E-08 24 415 "SYT9,ECSIT,SORCS1,HOGA1,ERICH3,PPFIA1,FXYD6,CAMTA1,ANO4,DDR1,CAMK2G,GRIA1,GRIA2,HPS5,PCDH9,MAGI1,UBTF,CMTM5,PRDM2,PCDH15,SLC25A18,PHC2,RNF220,ELAVL4" MicroRNA hsa-miR-3150b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-09 9.01E-06 4.07E-09 3.73E-08 18 230 "MRVI1,ARID1A,RPH3A,WDTC1,ASTN2,HAP1,PSD3,ZFP91,PFKFB3,SPATA6,SF1,CRMP1,MICAL2,BDNF-AS,DNM2,BSCL2,EN2,EPB41L1" MicroRNA hsa-miR-362-3p:TargetScan hsa-miR-362-3p TargetScan 1.74E-09 9.42E-06 4.24E-09 3.89E-08 19 259 "CHST15,GAS7,FAM168A,PRUNE2,PTBP2,OPCML,MFSD2A,PCSK2,CADM1,HPR,FAT3,CRMP1,CHD5,PRKACB,CTNND1,DPYSL5,PMEPA1,KIF2A,L1CAM" MicroRNA hsa-miR-936:PITA hsa-miR-936:PITA_TOP PITA 1.74E-09 9.42E-06 4.24E-09 3.89E-08 19 259 "CSMD3,LRRTM4,MAGI3,LRRC4C,API5,CCDC88A,SORCS3,PHYHIPL,MEGF11,CLASP2,COLGALT2,ERBIN,SYT4,CAMSAP2,PROX1,TMEM255A,ABI1,PAK5,SH3GLB1" MicroRNA hsa-miR-329-3p:TargetScan hsa-miR-329-3p TargetScan 1.74E-09 9.42E-06 4.24E-09 3.89E-08 19 259 "CHST15,GAS7,FAM168A,PRUNE2,PTBP2,OPCML,MFSD2A,PCSK2,CADM1,HPR,FAT3,CRMP1,CHD5,PRKACB,CTNND1,DPYSL5,PMEPA1,KIF2A,L1CAM" MicroRNA hsa-miR-214:PITA hsa-miR-214:PITA_TOP PITA 1.74E-09 9.43E-06 4.25E-09 3.90E-08 21 319 "ACLY,SCN3A,SEMA6A,FHL1,WDTC1,MYT1L,CAMTA1,GRIN1,FNDC5,CADM1,PLXNB3,RIMS4,PUM1,KIAA0513,RIMS3,SYNC,JAKMIP2,SRGAP3,PID1,FAM135B,PHC2" MicroRNA hsa-miR-518f:mirSVR_lowEffct hsa-miR-518f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-09 9.53E-06 4.29E-09 3.94E-08 29 595 "MAP6,EXTL1,ACTN2,WLS,PLEKHG5,FOXRED2,SCN3A,LRRC7,MOBP,BCAN,SHANK2,SON,MYT1L,GFAP,ADHFE1,ZEB1,NRGN,BRSK2,GRIA1,LINC00839,TPM3,BEST3,NRXN1,SULT4A1,SLC25A27,SIRPA,PTHLH,SRGAP3,BSCL2" MicroRNA hsa-miR-409-3p:TargetScan hsa-miR-409-3p TargetScan 1.78E-09 9.65E-06 4.34E-09 3.98E-08 18 231 "MAPT,MDM4,AQP4,SCN3B,SALL3,FAM168A,MMD2,NUDT21,AIFM1,HNRNPK,NXPH1,RAB39A,PLD5,KCNH1,DPP6,RBM12,GPR61,ABI2" MicroRNA hsa-miR-4784:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-09 9.65E-06 4.34E-09 3.98E-08 18 231 "MRVI1,ARID1A,RPH3A,WDTC1,ASTN2,HAP1,PSD3,ZFP91,PFKFB3,SPATA6,SF1,CRMP1,MICAL2,BDNF-AS,DNM2,BSCL2,EN2,EPB41L1" MicroRNA hsa-miR-7:PITA hsa-miR-7:PITA_TOP PITA 1.78E-09 9.65E-06 4.34E-09 3.98E-08 18 231 "CSMD3,ATP2B2,CLASP2,GLS,TCF12,DIRAS1,SYT6,OPCML,MAGI1,PDE4B,CCSER2,ST8SIA5,FMN2,NRSN1,FAM131B,WIPF2,RAB5B,ABI2" MicroRNA hsa-miR-555:mirSVR_highEffct hsa-miR-555:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-09 9.67E-06 4.35E-09 3.99E-08 25 451 "KIAA1109,SESN3,BCAN,USP16,SLC1A6,LRRC55,SLIT1,ASPH,SMARCE1,TMEM108,SOX5,ADHFE1,PTBP2,GRIA4,CCKBR,ZNF384,CASC2,CCSER2,DNAJC12,RBPJ,MAGI2,ZC3H11A,ABCC9,RET,SEC61A2" MicroRNA hsa-miR-605:PITA hsa-miR-605:PITA_TOP PITA 1.91E-09 1.03E-05 4.63E-09 4.25E-08 20 290 "F3,ADD3,NLGN4X,MYT1L,NEUROD1,NFIA,PCDH11X,ADGRL3,CACNA1A,NUMA1,CDC42,MAGI1,PDE3B,HNRNPK,CADM1,NSD2,MED1,PTCH1,SRGAP3,EPB41L1" MicroRNA hsa-miR-708:PITA hsa-miR-708:PITA_TOP PITA 1.91E-09 1.03E-05 4.64E-09 4.25E-08 15 154 "PDZD4,AMPH,ANK1,IGSF9B,NCAM1,GPM6A,GRIA4,DCLK1,HNRNPK,PRDM2,SNX27,WIPF2,JMJD1C,SH3GLB1,EN2" MicroRNA hsa-miR-365:mirSVR_highEffct hsa-miR-365:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.92E-09 1.04E-05 4.66E-09 4.27E-08 28 560 "ADD3,ERMN,FGF1,ANK3,GPAM,CACHD1,API5,CGREF1,USP33,ADGRB2,UNC5D,PRUNE2,LRIT2,PCDHGA3,GRIK4,MFSD2A,TLL2,PAX6,ZMYND8,BEST3,CNTN1,BTF3L4,FEZ1,VCAN,FMN2,LRP8,DTNA,ARHGAP12" MicroRNA "ACTGCCT,MIR-34B:MSigDB" "ACTGCCT,MIR-34B:MSigDB" MSigDB 1.95E-09 1.06E-05 4.74E-09 4.35E-08 17 205 "PLEKHG5,ADCY2,ELMOD1,ANK2,ITSN1,ARPP21,RAP1GAP2,NEUROD1,TCF12,GRID1,CELF3,MAGI1,CTNND2,TOX,ARNT2,ARHGEF10L,RBM12" MicroRNA hsa-miR-103a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.95E-09 1.06E-05 4.74E-09 4.35E-08 25 453 "MDM4,CLIP1,ADORA3,SEMA6A,SLC6A9,SMARCE1,SON,MYBPC1,CAB39,NFIA,EML4,CYB561A3,TGFBR3,TJP1,TPD52,PPP2R5C,OSBPL3,VCAN,PRKAB2,RIMS3,JAKMIP2,TMEM255A,GOPC,EN2,TMEM100" MicroRNA hsa-miR-422a:PITA hsa-miR-422a:PITA_TOP PITA 1.95E-09 1.06E-05 4.74E-09 4.35E-08 14 131 "FOXG1,CAPRIN2,ZCCHC24,CAB39,BCL2L2,NEUROD1,ANO4,TCF12,GRIK2,LGI1,KIF2A,CALN1,DSCAM,VANGL2" MicroRNA hsa-miR-378:PITA hsa-miR-378:PITA_TOP PITA 1.95E-09 1.06E-05 4.74E-09 4.35E-08 14 131 "FOXG1,CAPRIN2,ZCCHC24,CAB39,BCL2L2,NEUROD1,ANO4,TCF12,GRIK2,LGI1,KIF2A,CALN1,DSCAM,VANGL2" MicroRNA hsa-miR-1246:PITA hsa-miR-1246:PITA_TOP PITA 2.05E-09 1.11E-05 4.96E-09 4.55E-08 18 233 "WAC,SCN3A,SEMA6A,CCDC88A,CPLX2,BCL2L2,CAMK2G,PSD3,TPD52,CADM1,NRXN1,WBP1L,PTCH1,MAGI2,SMG7,SNX27,DLG3,TMEM255A" MicroRNA hsa-miR-224-5p:TargetScan hsa-miR-224-5p TargetScan 2.06E-09 1.11E-05 4.99E-09 4.57E-08 21 322 "ACER3,RBM10,CDHR1,APBA2,MAGI3,BCL2L2,NFIA,GPM6A,CYB561A3,OPCML,PDE1C,FNDC5,CADM1,MED1,MAPK8,HES5,DPYSL5,KCNH1,L1CAM,EFNA3,RPRD1A" MicroRNA hsa-let-7i*:mirSVR_highEffct hsa-let-7i*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-09 1.13E-05 5.06E-09 4.64E-08 15 155 "ADGRV1,SEMA6A,FOXG1,MOG,CADPS,PHYHIPL,STOX1,ADHFE1,CNDP1,VSTM2A,GRIA2,GRIA4,CTNND1,KCNN3,RTN4" MicroRNA hsa-miR-517a:mirSVR_lowEffct hsa-miR-517a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-09 1.13E-05 5.06E-09 4.64E-08 22 354 "CDHR1,RTN3,MOBP,TRIM46,PKP4,DACH2,RCOR3,EIF4G3,WDTC1,NEUROD1,GPR19,BRSK2,LINC00839,CDK11B,SEMA5B,SLC36A4,PRKCZ,DNAJC6,JAKMIP2,PEX5,DTNA,ZYG11B" MicroRNA hsa-miR-1827:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-09 1.15E-05 5.14E-09 4.72E-08 35 837 "SDE2,MDM4,PLEKHG5,KLHL32,SLC30A10,MAGI3,CCDC80,KIAA1614,SFMBT2,SLC2A5,ATM,SCN3B,B4GALNT1,KIF1B,FAM168A,ACSBG1,ZNF638,GNG4,DDR1,PTBP2,NUCB1,BRSK2,AKNA,TPM3,GPR37L1,SCRG1,CCSER2,MFSD4A,KIAA0513,PTPRE,SNX27,DNAH9,PLEKHB2,PARP11,SYT15" MicroRNA hsa-miR-155-5p:TargetScan hsa-miR-155-5p TargetScan 2.13E-09 1.15E-05 5.15E-09 4.72E-08 23 387 "APC,ASTN1,NRG3,PALLD,CAB39,NFASC,FAM168A,NFIA,GNAS,GPM6B,REPS2,NMT2,FTO,PKN2,PLD5,PROX1,KCNA1,PTPRD,BSDC1,PHC2,SEC61A2,ELAVL4,EN2" MicroRNA hsa-miR-27b-3p:Functional MTI Functional MTI miRTarbase 2.17E-09 1.18E-05 5.26E-09 4.82E-08 24 421 "DPF1,SLC25A25,ADAR,TOMM40L,SEMA6A,GPAM,WDTC1,CAB39,KIF1B,NUDT21,OLR1,TGFBR3,ZNF384,PNKD,RGS6,CTNND1,BDNF-AS,ELMO1,ZC3H11A,CAB39L,ATN1,RET,PHC2,EN2" MicroRNA hsa-miR-1257:PITA hsa-miR-1257:PITA_TOP PITA 2.30E-09 1.25E-05 5.56E-09 5.10E-08 16 181 "ARID1A,ERMN,PPM1E,GPAM,NLGN1,CCDC88A,CADPS,LMO3,RND1,BTF3L4,TENM4,DNAJC6,KCNA1,PTPRD,SMG7,SFXN5" MicroRNA hsa-miR-6124:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-09 1.25E-05 5.56E-09 5.10E-08 16 181 "CCDC80,BCAN,NASP,GNG3,PRUNE2,FAM69C,USP2,TPM3,UBTF,VAV2,SF1,CTNND1,KIAA0513,CSDE1,KCND3,ABCC9" MicroRNA hsa-miR-500:PITA hsa-miR-500:PITA_TOP PITA 2.43E-09 1.31E-05 5.86E-09 5.37E-08 21 325 "LGR4,EYA1,SCN3A,CACHD1,PKNOX2,CCDC88A,RCOR3,ERBIN,GPM6B,PSD3,ZNF384,NEGR1,NXPH1,POU3F2,HES5,RIMS3,SYNC,LRRTM3,PTPRD,RBM12,ELAVL4" MicroRNA hsa-miR-379:mirSVR_highEffct hsa-miR-379:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.46E-09 1.33E-05 5.95E-09 5.46E-08 23 390 "SDE2,LRRC7,ERICH3,PKP4,SLITRK3,ZNF365,MSR1,CCDC88A,CAPRIN2,TMEM108,ATP1A2,SEMA4A,ADGRL3,MAGI1,HMGB1,MEAF6,SYNC,RABGAP1L,KCNK2,PEX5,DPP6,ABI1,VWA5A" MicroRNA hsa-miR-423-5p:TargetScan hsa-miR-423-5p TargetScan 2.49E-09 1.35E-05 6.01E-09 5.52E-08 15 157 "ACHE,CADM3,NMNAT2,FAM168A,CNTN2,NUCB1,RFFL,FBXL16,DAAM2,DLGAP3,NRXN2,RIMS4,RAB5B,EFNA3,ELAVL3" MicroRNA hsa-miR-1304:PITA hsa-miR-1304:PITA_TOP PITA 2.63E-09 1.43E-05 6.35E-09 5.82E-08 14 134 "LRRC7,BCAN,CAPRIN2,SOX5,TIE1,CCSER2,POU3F2,WBP1L,SYTL2,TOMM20,RAB5B,SLC17A6,GOPC,EPB41L2" MicroRNA hsa-miR-377-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.70E-09 1.46E-05 6.52E-09 5.98E-08 19 266 "ARID1A,ADCYAP1R1,GOLGA7B,CADPS,ATM,CADM3,FXYD6,SEPT3,EML4,GRID1,ZDHHC22,DUSP26,NCAN,PROX1,LRP8,KCNA4,KCNK1,ZYG11B,ARHGAP12" MicroRNA hsa-miR-938:mirSVR_highEffct hsa-miR-938:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-09 1.48E-05 6.60E-09 6.05E-08 24 426 "ACLY,ADAR,ADD3,FHL1,NTNG1,CACHD1,SHTN1,MIER1,RCOR3,FXYD6,SEPT3,ADGRL3,GPM6A,TCF7L2,NUMA1,ADAMTS8,TPD52,MAGI1,SPATA6,POU3F2,PNKD,SNCAIP,TOMM20,TMEM100" MicroRNA hsa-miR-571:PITA hsa-miR-571:PITA_TOP PITA 2.80E-09 1.52E-05 6.74E-09 6.18E-08 12 92 "RTKN,DSCAML1,ARHGAP5,KIF21B,RAP1GAP2,CAMSAP2,NLGN3,SF1,FMN2,DPYSL5,KCNMA1,RAB5B" MicroRNA hsa-miR-95:mirSVR_lowEffct hsa-miR-95:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.85E-09 1.54E-05 6.85E-09 6.29E-08 22 360 "ATAT1,ARID1A,TESK2,LINC00461,ASIC4,ELMOD1,TRIM46,DGKD,SON,WDTC1,MYRF,EML4,VSTM2A,GRIA1,JAM2,NSD2,CNRIP1,MED1,EDRF1,LRRTM3,PCDH15,NAV2" MicroRNA hsa-miR-132*:mirSVR_lowEffct hsa-miR-132*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.87E-09 1.55E-05 6.90E-09 6.33E-08 24 427 "DPF1,PRR5L,ADAR,ITSN1,APBA2,SLC8A3,NSG2,CADPS,ARFGAP1,ATM,RND1,AKNA,GRIA2,PTPN5,MFSD2A,PDE2A,GDAP1L1,OPALIN,PLCH2,RBPJ,HES5,WBP1L,GON4L,DNM2" MicroRNA "TGTATGA,MIR-485-3P:MSigDB" "TGTATGA,MIR-485-3P:MSigDB" MSigDB 2.90E-09 1.57E-05 6.98E-09 6.40E-08 14 135 "ARID1A,ANK3,API5,GAD2,CPLX2,GANAB,TBX15,GPM6A,GRID1,NRXN1,NXPH1,MAGI2,KCNMA1,RNF220" MicroRNA hsa-miR-720:mirSVR_lowEffct hsa-miR-720:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.17E-09 1.71E-05 7.61E-09 6.98E-08 25 464 "SCN4B,FGF14,ARFGAP1,ATP1A2,SCN3B,ZCCHC24,ZSWIM8,ADGRB2,ARHGEF7,CASTOR3,CAMTA1,MMD2,CACNA1A,BRSK2,GRIA1,COL9A2,RGS6,PRKCZ,NRSN1,CNIH3,PRDM2,KCNK2,NAV2,SNX27,ZNF248" MicroRNA hsa-miR-943:PITA hsa-miR-943:PITA_TOP PITA 3.24E-09 1.75E-05 7.78E-09 7.14E-08 15 160 "MBP,HPCAL4,AMPH,MAGI3,SLC1A2,NFIA,MAEL,ZNF384,HNRNPK,NEGR1,ARHGEF4,CEP170,OLFM3,DLG2,RGS7" MicroRNA hsa-miR-4301:mirSVR_highEffct hsa-miR-4301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.29E-09 1.78E-05 7.90E-09 7.25E-08 23 396 "MEG3,ERMN,BCAR3,FHL1,SGIP1,CNIH2,PPFIA1,CCDC88A,CAPRIN2,USP33,NPAS3,ZNF302,TBX15,GRIA2,MAGI1,PDE1C,CTNND1,PTPRD,KCNC1,PCDH15,DTNA,SLC6A15,SLC4A10" MicroRNA hsa-miR-216a:PITA hsa-miR-216a:PITA_TOP PITA 3.31E-09 1.79E-05 7.95E-09 7.30E-08 22 363 "ARID1A,MAGI3,MEGF11,SOX5,KIF21B,CPLX2,ADGRL3,EML4,ZFP91,MAGI1,CADM1,FAT3,CTNND2,PMEPA1,CNIH3,TMEM255A,ZYG11B,VANGL2,RBM12,EN2,OLIG2,RCAN2" MicroRNA hsa-miR-1910-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-09 1.82E-05 8.05E-09 7.38E-08 26 501 "SDE2,PLEKHG5,PNMA8B,SLC30A10,MAGI3,CCDC80,DNAH17,ATM,TMEM151A,SCN3B,KIF1B,ACSBG1,GNG4,CAMSAP2,DDR1,NUCB1,RBFOX2,TPM3,SCRG1,DLGAP3,CCSER2,RBPJ,DPYSL5,SNX27,RAB5B,PLEKHB2" MicroRNA hsa-miR-890:PITA hsa-miR-890:PITA_TOP PITA 3.49E-09 1.89E-05 8.37E-09 7.68E-08 18 241 "ANK1,MAGI3,AQP4,ARHGAP5,GAD2,AHCYL1,B4GALNT1,RGL1,EML4,OPCML,RBFOX2,NSD2,PPP2R5C,ELMO1,PTPRD,L1CAM,VANGL2,EPB41L2" MicroRNA hsa-miR-606:PITA hsa-miR-606:PITA_TOP PITA 3.60E-09 1.95E-05 8.64E-09 7.93E-08 20 301 "RIMKLA,EYA1,SFPQ,PPM1E,NLGN1,SHTN1,CCDC88A,SCG3,RCOR3,CAMTA1,VXN,OPCML,REPS2,RBFOX2,ACBD5,DPYSL5,DLG3,TMEM255A,SLC17A6,EPB41" MicroRNA hsa-miR-99a*:mirSVR_highEffct hsa-miR-99a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.68E-09 1.99E-05 8.82E-09 8.10E-08 13 115 "CNTNAP3,WAC,SLC1A7,SORCS3,MYBPC1,TTLL9,ARHGEF7,TCF7L2,FEZ2,PKN2,PRTFDC1,TMEM255A,ZYG11B" MicroRNA "GAGCCAG,MIR-149:MSigDB" "GAGCCAG,MIR-149:MSigDB" MSigDB 3.87E-09 2.10E-05 9.27E-09 8.50E-08 14 138 "ACLY,ARID1A,B3GAT1,SNCB,MIR4697HG,BCL2L2,NCDN,PHLDB1,TCF12,FBXL16,SF1,RIMS4,NAV2,FAM57B" MicroRNA hsa-miR-1236-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.98E-09 2.15E-05 9.52E-09 8.74E-08 18 243 "SLC25A25,GRAMD1B,TMEM156,MYBPC1,VAMP1,ZNF638,NODAL,KLHL4,ZEB1,GPR26,PTGDR2,HMGB1,SLC22A6,PNKD,TENM4,NUP214,ABI2,EPB41" MicroRNA hsa-miR-1468:mirSVR_highEffct hsa-miR-1468:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.05E-09 2.19E-05 9.69E-09 8.89E-08 22 367 "ADD3,SORCS1,ITSN1,SYBU,NLGN1,ST3GAL3,SCG3,NCAM1,GLS,CAMK2G,PTPN5,PIK3CD,MEAF6,NXPH1,EDRF1,SV2A,TMEM255A,DTNA,RGS7,ATL1,VWA5A,OLIG2" MicroRNA hsa-miR-4322:mirSVR_highEffct hsa-miR-4322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.09E-09 2.22E-05 9.79E-09 8.99E-08 25 470 "MDM4,CSMD3,AGT,APC,SLC1A7,ARFGAP2,SLC8A3,WDTC1,ZSWIM8,ENKUR,LMO3,CACNB2,GRIA1,AIFM1,HPS5,PADI2,CAMKV,CRLS1,SNCAIP,WBP1L,CEP170,KCNJ4,KCNN3,RAD52,FAM13C" MicroRNA hsa-miR-1281:mirSVR_lowEffct hsa-miR-1281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-09 2.22E-05 9.82E-09 9.01E-08 29 618 "ASIC4,TRIM46,APBA2,SLC1A7,CSPG5,TMEM108,KIF21B,CASTOR3,GNAS,ANO4,VXN,AKNA,GRIA2,P2RX7,CDC42,CASC2,JAM2,A2ML1,FADS2,SLC25A27,MFSD4A,CSF3R,ATRNL1,KIAA1755,GON4L,DLG2,ZYG11B,RFX4,SFXN5" MicroRNA hsa-miR-4635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.15E-09 2.25E-05 9.91E-09 9.09E-08 21 335 "FAM43B,AMER2,ANK1,CCDC80,NAXD,MTR,RCOR3,KIF1B,ERBIN,TMEM136,CACNB2,PCDH9,TPM3,MEAF6,ATCAY,PTAFR,KCNN3,CALN1,C12orf4,SH3GLB1,ELAVL4" MicroRNA hsa-miR-5197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-09 2.26E-05 9.99E-09 9.17E-08 15 163 "MOG,MIER1,RPH3A,SFMBT2,ERBIN,HAP1,ZFP91,GPR37L1,PACSIN1,PTPA,VCAN,RIMS3,TOMM20,WIPF2,RAB5B" MicroRNA hsa-miR-3148:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-09 2.30E-05 1.01E-08 9.29E-08 18 244 "MDM4,SOX6,SESN3,BCAN,NASP,NCAM1,PRUNE2,FAM69C,ZFP91,RBFOX2,TPM3,TPM4,CTNND1,KIAA0513,RTN4,ABCC9,ZYG11B,EN2" MicroRNA hsa-miR-632:PITA hsa-miR-632:PITA_TOP PITA 4.25E-09 2.30E-05 1.02E-08 9.31E-08 14 139 "SORBS1,AQP4,SLC1A2,SORCS3,CADM3,NCDN,PTPN5,RBFOX2,NLGN3,KIAA1549L,NXPH1,SF1,PKN2,EPB41L1" MicroRNA "ACTTTAT,MIR-142-5P:MSigDB" "ACTTTAT,MIR-142-5P:MSigDB" MSigDB 4.40E-09 2.38E-05 1.05E-08 9.63E-08 19 274 "RTN1,GAS7,SORBS1,SHANK2,SON,SOX5,LUZP2,CAMTA1,ADGRL3,TCF12,CAMK2A,GPR88,SLC25A27,FAM131B,RGMA,ATG16L1,GOPC,JMJD1C,ELAVL4" MicroRNA hsa-miR-487a:PITA hsa-miR-487a:PITA_TOP PITA 4.52E-09 2.45E-05 1.08E-08 9.90E-08 18 245 "CSMD3,YPEL4,ASTN1,GAD2,CPLX2,SPART,ZNF638,SYT4,GPM6A,REPS2,PTCH1,MAGI2,ZC3H11A,SMG7,RAB5B,FAM13C,RFX5,RNF220" MicroRNA "GTATTAT,MIR-369-3P:MSigDB" "GTATTAT,MIR-369-3P:MSigDB" MSigDB 4.65E-09 2.52E-05 1.11E-08 1.02E-07 16 190 "EYA1,CHST15,ELMOD1,FOXG1,ST3GAL3,BCAS1,FYN,TCF12,PAX6,PDE4B,DNAJC6,PLPPR4,GOPC,RFX4,PIANP,SEZ6" MicroRNA hsa-miR-371a-5p:TargetScan hsa-miR-371a-5p TargetScan 4.67E-09 2.53E-05 1.11E-08 1.02E-07 19 275 "RTN3,PKP4,PKNOX2,ATP1A2,ATP2B2,NEUROD1,PTBP2,CAMK2G,PAH,PCDH8,SCRG1,DLGAP3,NEGR1,FTO,BTF3L4,ANKS1B,CADM2,DNAH9,RCAN2" MicroRNA hsa-miR-4455:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.94E-09 2.68E-05 1.18E-08 1.08E-07 15 165 "FGF14,RPH3A,NMNAT2,KIF1B,FAM69C,ZEB1,TMEM151B,TNR,KIAA1549L,NCAN,MAPK10,DNAJC6,JAKMIP2,TTLL7,EN2" MicroRNA hsa-miR-542-3p:PITA hsa-miR-542-3p:PITA_TOP PITA 5.01E-09 2.71E-05 1.19E-08 1.10E-07 16 191 "SCN3A,ZCCHC17,ARHGAP5,SORCS3,PHYHIPL,TCF12,PSD3,SERPINE2,NOMO2,ANLN,TUBB2B,MAGI2,KCNA1,SMG7,INSYN2,EPB41L1" MicroRNA hsa-miR-4266:mirSVR_highEffct hsa-miR-4266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.03E-09 2.72E-05 1.20E-08 1.10E-07 26 511 "MBP,LGR4,MRVI1,ARID1A,MDM4,SLC44A5,LRRTM4,ERICH3,ITSN1,ZCCHC17,ZNF365,DACH2,SLCO1A2,PHYHIPL,MYBPC1,ADGRB2,GLS,GPM6B,GRIA2,TF,C11orf49,PPP2R5C,PRKACB,CEP170,AK5,TMEM255A" MicroRNA "CTCTGGA,MIR-520A:MSigDB" "CTCTGGA,MIR-520A:MSigDB" MSigDB 5.12E-09 2.77E-05 1.22E-08 1.12E-07 14 141 "SON,SMOC1,CAMK2A,CAMK2G,NUMA1,ZFP91,TPM3,CDH20,TMCC2,SNX27,ATG16L1,PAK5,RNF220,RBM12" MicroRNA hsa-miR-510:PITA hsa-miR-510:PITA_TOP PITA 5.12E-09 2.77E-05 1.22E-08 1.12E-07 14 141 "MRVI1,ST8SIA1,GFRA1,FAM168A,CAMK2G,REPS2,ARHGAP19,MAGI1,CCDC136,SF1,ZC3H11A,RET,PHC2,RCAN2" MicroRNA "CTCTGGA,MIR-525:MSigDB" "CTCTGGA,MIR-525:MSigDB" MSigDB 5.12E-09 2.77E-05 1.22E-08 1.12E-07 14 141 "SON,SMOC1,CAMK2A,CAMK2G,NUMA1,ZFP91,TPM3,CDH20,TMCC2,SNX27,ATG16L1,PAK5,RNF220,RBM12" MicroRNA hsa-miR-521:mirSVR_lowEffct hsa-miR-521:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-09 2.80E-05 1.23E-08 1.13E-07 22 372 "PLEKHG5,MOBP,CAB39,TTLL9,GNAS,ACSL6,DDR1,VWCE,TLX1,A2ML1,PACSIN1,CRMP1,SNCAIP,OSBPL3,NRSN1,PRDM2,PTPRD,PTPRE,DLG3,DPP6,INSYN2,SIDT2" MicroRNA hsa-miR-1263:PITA hsa-miR-1263:PITA_TOP PITA 5.18E-09 2.81E-05 1.23E-08 1.13E-07 12 97 "PPM1E,RUFY2,ARHGAP5,CADPS,PHLDB1,NEUROD1,CACNA1A,PCDH9,BEST1,MAPK10,KCNJ10,EFNA3" MicroRNA hsa-miR-7111-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-09 2.87E-05 1.26E-08 1.16E-07 17 219 "SERPINA3,SLC25A25,ASIC4,SMARCE1,ACSBG1,ZNF638,GRIK3,TGFBR3,PTGDR2,RBFOX2,SLC22A6,GDAP1L1,KIAA0408,DPYSL5,SMG7,TMCC2,KCNN3" MicroRNA hsa-let-7c:PITA hsa-let-7c:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-miR-98:PITA hsa-miR-98:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7f:PITA hsa-let-7f:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7d:PITA hsa-let-7d:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7i:PITA hsa-let-7i:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7a:PITA hsa-let-7a:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7g:PITA hsa-let-7g:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-let-7b:PITA hsa-let-7b:PITA_TOP PITA 5.43E-09 2.94E-05 1.29E-08 1.18E-07 22 373 "LGR4,RTKN,SNX30,SCN4B,GAS7,SLC8A2,KIF21B,CLASP2,ACSL6,GPR26,ADAMTS8,TNFRSF1B,SLC25A27,BTF3L4,PRRX1,PNKD,RGS6,OSBPL3,PRKAB2,BLOC1S6,PTPRD,VANGL2" MicroRNA hsa-miR-602:mirSVR_highEffct hsa-miR-602:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.62E-09 3.04E-05 1.33E-08 1.22E-07 14 142 "ARID1A,WAC,FOXG1,MSR1,SNAP25,SMOC1,NELL1,RGL1,NUMA1,CASC2,KIAA1549L,RGMA,ARHGEF10L,RASGRP2" MicroRNA hsa-miR-4304:mirSVR_lowEffct hsa-miR-4304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.73E-09 3.10E-05 1.35E-08 1.24E-07 25 478 "CLIP1,KLHL32,ERMN,KIAA1109,FHL1,FOXG1,USP16,CADPS,SPHKAP,NRG3,SON,SLCO1C1,KAZN,BRSK2,P2RX7,MEAF6,SNCAIP,PTCH1,PTHLH,KCNC1,KCNK1,KCNMA1,DTNA,TTLL7,VWA5A" MicroRNA "ATACTGT,MIR-144:MSigDB" "ATACTGT,MIR-144:MSigDB" MSigDB 5.82E-09 3.15E-05 1.38E-08 1.26E-07 16 193 "LGR4,ARID1A,SEMA6A,FOXG1,ANK2,CACHD1,CCDC88A,SORCS3,ATP2B2,SON,FMN2,PUM1,PTHLH,RFX4,RBM12,EPB41" MicroRNA hsa-miR-122-5p:TargetScan hsa-miR-122-5p TargetScan 5.83E-09 3.16E-05 1.38E-08 1.26E-07 15 167 "RIMKLA,FGF1,NPAS3,RAP1GAP2,DDR2,NEGR1,BEST1,CTNND2,ECE2,MASP1,CADM2,RGMA,DLG2,PLEKHB2,PLEKHO1" MicroRNA hsa-miR-549:PITA hsa-miR-549:PITA_TOP PITA 5.83E-09 3.16E-05 1.38E-08 1.26E-07 15 167 "WLS,SLC25A25,NLGN4X,SLC30A10,GAS7,ARHGAP5,ZFP91,PCSK2,HMGB1,POU3F2,KIAA0513,HP1BP3,DLG2,HS3ST4,VANGL2" MicroRNA hsa-miR-5088-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.83E-09 3.16E-05 1.38E-08 1.26E-07 15 167 "FAM43B,ADCYAP1R1,ASIC4,C10orf105,TMEM151A,DKK3,CAMK2G,VWCE,NEURL1,PADI2,MEAF6,ZBTB16,KCNJ9,ZYG11B,ELAVL3" MicroRNA hsa-miR-600:PITA hsa-miR-600:PITA_TOP PITA 5.83E-09 3.16E-05 1.38E-08 1.26E-07 18 249 "GPR158,FOXG1,ANK1,NTNG1,MYT1L,TCF12,PTBP2,GRIA4,INA,TNS1,PCDH8,NEGR1,UBTF,MAGI2,PTPRD,DNM2,SLC4A10,ELAVL3" MicroRNA hsa-miR-4296:mirSVR_highEffct hsa-miR-4296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.85E-09 3.17E-05 1.38E-08 1.27E-07 24 443 "MDM4,CSMD3,AGT,APC,SLC1A7,ARFGAP2,SLC8A3,ZSWIM8,ENKUR,LMO3,CACNB2,GRIA1,AIFM1,HPS5,PADI2,CAMKV,CRLS1,SNCAIP,WBP1L,CEP170,KCNJ4,KCNN3,RAD52,FAM13C" MicroRNA hsa-miR-4258:mirSVR_lowEffct hsa-miR-4258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.96E-09 3.23E-05 1.41E-08 1.29E-07 21 342 "LOC100128239,ECSIT,GOLGA7B,ARFGAP2,CGREF1,ARFGAP1,TMEM151A,EIF4G3,ZSWIM8,KIF1B,RCOR2,FGF17,ACSBG1,ZNF638,PCDHGA3,NOMO2,MICAL2,GON4L,KCNQ2,PARP11,OLIG2" MicroRNA hsa-miR-4308:mirSVR_highEffct hsa-miR-4308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.97E-09 3.23E-05 1.41E-08 1.29E-07 25 479 "RCSD1,ADD3,HOGA1,FGF14,MOBP,SCG3,CAPRIN2,DKK3,EMC1,NFASC,PCDH11X,UNC5D,ATF7,CACNB2,GRIA4,GRIK3,PDYN,TJP2,ACBD5,PRDM2,RABGAP1L,DLG2,ATG16L1,VWA5A,EPB41L2" MicroRNA hsa-miR-184:mirSVR_highEffct hsa-miR-184:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.08E-09 3.29E-05 1.43E-08 1.31E-07 17 221 "MBP,MEG3,PLA2G6,FGF14,NTNG1,MIER1,B4GALNT1,ADHFE1,VXN,PDE4B,SF1,FMN2,BLOC1S6,DPP6,DTNA,SIDT2,EPB41L2" MicroRNA hsa-miR-631:mirSVR_highEffct hsa-miR-631:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.32E-09 3.42E-05 1.49E-08 1.36E-07 23 410 "ACER3,F3,LINC00461,PKP4,GPAM,MIER1,SORCS3,ATP2B2,NELL1,ACSBG1,RFFL,C1orf94,MAGI1,HEPACAM,SNCAIP,VCAN,ECE2,STMN4,ZC3H11A,KCNA1,PTPRE,SLC25A48,RET" MicroRNA hsa-miR-619:PITA hsa-miR-619:PITA_TOP PITA 6.33E-09 3.43E-05 1.49E-08 1.37E-07 15 168 "SYT9,FOXG1,CAB39,TGFBR3,PCDH9,PDE3B,RBPJ,FAM131B,CA10,STMN4,PTPRD,WIPF2,PHC2,RBM12,EPB41" MicroRNA hsa-miR-933:mirSVR_lowEffct hsa-miR-933:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.59E-09 3.57E-05 1.55E-08 1.42E-07 22 377 "F3,PLA2G6,PDZD4,GPAM,ARFGAP2,SHANK2,IGSF9B,KIF1B,BCL2L2,GNAS,GRIK2,ZFP91,FNDC5,SLC22A6,A2ML1,PRKACB,ECE2,NUP214,JMJD1C,RNF220,PIANP,YY1AP1" MicroRNA hsa-miR-519b-3p:Functional MTI Functional MTI miRTarbase 6.60E-09 3.58E-05 1.55E-08 1.42E-07 21 344 "ATAT1,ADAR,F3,ADARB2,SESN3,CAPRIN2,SALL3,SMOC1,CAMSAP2,TCF7L2,DDR2,PSD3,ZFYVE9,UBTF,BTF3L4,CSDE1,WIPF2,RAB5B,PLEKHB2,ARHGAP12,UEVLD" MicroRNA hsa-miR-1201:mirSVR_highEffct hsa-miR-1201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.85E-09 3.71E-05 1.61E-08 1.48E-07 27 556 "SDE2,PRR5L,SYT9,ADAR,SLC8A3,CGREF1,CAB39,ARPP21,SALL3,PCDH11X,ZNF638,PTBP2,EML4,NUMA1,CCKBR,CD81,MAEL,IGSF21,ZNF384,RBPJ,FMN2,PLPPR5,KCNA4,AK5,DPP6,DTNA,ABCC9" MicroRNA hsa-miR-651:PITA hsa-miR-651:PITA_TOP PITA 6.86E-09 3.72E-05 1.61E-08 1.48E-07 15 169 "SLITRK1,SEMA6A,SLITRK3,ASCL1,CLASP2,DCAF5,GFRA1,PCSK2,CNTN1,PPP3CB,PUM1,MAGI2,KCNMA1,PAK5,SLC4A10" MicroRNA hsa-miR-708-5p:TargetScan hsa-miR-708-5p TargetScan 6.86E-09 3.72E-05 1.61E-08 1.48E-07 15 169 "ACHE,PDZD4,KIAA1614,DKK3,GPM6A,GPR88,HNRNPK,RIMS3,GON4L,KCND3,KCNH1,KCNN3,PIANP,RPRD1A,EN2" MicroRNA hsa-miR-28-5p:TargetScan hsa-miR-28-5p TargetScan 6.86E-09 3.72E-05 1.61E-08 1.48E-07 15 169 "ACHE,PDZD4,KIAA1614,DKK3,GPM6A,GPR88,HNRNPK,RIMS3,GON4L,KCND3,KCNH1,KCNN3,PIANP,RPRD1A,EN2" MicroRNA hsa-miR-675:mirSVR_lowEffct hsa-miR-675:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.92E-09 3.75E-05 1.62E-08 1.49E-07 23 412 "SORBS1,SLC8A3,DLL3,ATP2B2,STARD10,AJAP1,NRGN,SYT6,NUMA1,BRSK2,ASIC3,TLX1,FADS2,PLXNB3,C11orf49,MICAL2,KCNK1,PYGM,GNE,NUP214,RGS7,SEC61A2,EPB41L2" MicroRNA hsa-miR-532-5p:PITA hsa-miR-532-5p:PITA_TOP PITA 6.96E-09 3.77E-05 1.63E-08 1.50E-07 17 223 "SLITRK1,PPM1E,CACHD1,VAMP1,CAMK2G,GRIA4,TLL2,ZFP91,CDC42,PCDH9,DCLK1,RBFOX2,PDE1C,NEGR1,CTNND2,PAK5,RAVER2" MicroRNA hsa-miR-4265:mirSVR_highEffct hsa-miR-4265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.26E-09 3.93E-05 1.70E-08 1.56E-07 24 448 "MDM4,CSMD3,AGT,APC,SLC1A7,ARFGAP2,SLC8A3,ZSWIM8,ENKUR,LMO3,CACNB2,GRIA1,AIFM1,HPS5,PADI2,CAMKV,CRLS1,SNCAIP,WBP1L,CEP170,KCNJ4,KCNN3,RAD52,FAM13C" MicroRNA "ACACTGG,MIR-199A:MSigDB" "ACACTGG,MIR-199A:MSigDB" MSigDB 7.36E-09 3.99E-05 1.72E-08 1.58E-07 14 145 "ARID1A,ANK2,NTNG1,ATP2B2,WDTC1,KIF1B,GANAB,MYRF,BTRC,DDR1,ZFP91,RGMA,ARHGAP12,EPB41L1" MicroRNA "ACACTGG,MIR-199B:MSigDB" "ACACTGG,MIR-199B:MSigDB" MSigDB 7.36E-09 3.99E-05 1.72E-08 1.58E-07 14 145 "ARID1A,ANK2,NTNG1,ATP2B2,WDTC1,KIF1B,GANAB,MYRF,BTRC,DDR1,ZFP91,RGMA,ARHGAP12,EPB41L1" MicroRNA hsa-miR-744*:mirSVR_highEffct hsa-miR-744*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.39E-09 4.00E-05 1.73E-08 1.59E-07 28 596 "WLS,KLHL32,FABP7,FOXG1,AMPH,ERICH3,PPFIA1,PPM1E,SHTN1,RUFY2,RCOR3,SON,TBX15,GPM6B,PTBP2,GRIA4,CRB1,PTPN5,TMEFF2,HPCA,A2ML1,SPATA6,NRSN1,TOX,SLC25A48,PARP11,DBX2,SSPN" MicroRNA "TACTTGA,MIR-26B:MSigDB" "TACTTGA,MIR-26B:MSigDB" MSigDB 7.45E-09 4.03E-05 1.74E-08 1.60E-07 19 283 "LGR4,RTN1,AMPH,APC,SHTN1,ATM,ATP1A2,ZCCHC24,NEK6,CLASP2,VAMP1,PSD3,PCDH9,PFKFB3,ACBD5,PPP3CB,CTNND2,KCNK1,VANGL2" MicroRNA "TACTTGA,MIR-26A:MSigDB" "TACTTGA,MIR-26A:MSigDB" MSigDB 7.45E-09 4.03E-05 1.74E-08 1.60E-07 19 283 "LGR4,RTN1,AMPH,APC,SHTN1,ATM,ATP1A2,ZCCHC24,NEK6,CLASP2,VAMP1,PSD3,PCDH9,PFKFB3,ACBD5,PPP3CB,CTNND2,KCNK1,VANGL2" MicroRNA hsa-miR-30c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.47E-09 4.05E-05 1.75E-08 1.60E-07 26 521 "SDE2,CDC7,CHST15,SEMA6A,FOXG1,ARFGAP1,MTR,SMARCE1,ATM,EML4,AIFM1,CDC42,ZMYND8,HNRNPK,CAMKV,MED1,PNKD,PPP3CB,PRKAB2,MAPK8,CSDE1,RTN4,SEC61A2,RNF220,ABI2,EPB41" MicroRNA "ATTCTTT,MIR-186:MSigDB" "ATTCTTT,MIR-186:MSigDB" MSigDB 7.48E-09 4.05E-05 1.75E-08 1.60E-07 18 253 "BCAR3,RASA3,MIER1,BRINP2,MYT1L,AHCYL1,NASP,P2RX7,CDC42,RBFOX2,NEGR1,NXPH1,CSDE1,ZC3H11A,PLPPR4,KCNMA1,SNX27,PAK5" MicroRNA hsa-miR-149:mirSVR_highEffct hsa-miR-149:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.01E-09 4.34E-05 1.87E-08 1.72E-07 32 757 "ZFYVE27,SORCS1,CCDC80,CACHD1,ZNF365,SORCS3,NCAM1,ZNF302,POPDC3,DDR1,CACNB2,TCF12,OLR1,LINC00839,FBXL16,ARHGAP19,FNDC5,BEST3,ASIC3,CASC2,SF1,SNCAIP,PSMD13,PRDM2,PTPRO,RABGAP1L,PCDH15,KCNMA1,KIF2A,RGR,JMJD1C,ZNF248" MicroRNA hsa-miR-330-3p:Functional MTI Functional MTI miRTarbase 8.05E-09 4.36E-05 1.88E-08 1.72E-07 14 146 "TOMM40L,SH3GL2,BCAS1,TGFBR3,GUCY1A2,CDC42,PRMT8,PFKFB3,NEGR1,CRLS1,ZBTB16,PLEKHB2,EFNA3,ARHGAP12" MicroRNA hsa-miR-670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-09 4.55E-05 1.96E-08 1.80E-07 16 198 "SLC25A25,GRAMD1B,NLGN1,SLC7A14,SLC2A5,SLIT1,ACSL6,GRID1,GRIK3,TGFBR3,PTGDR2,HMGB1,SLC22A6,TOMM20,FAM13C,JMJD1C" MicroRNA hsa-miR-519a-3p:Functional MTI Functional MTI miRTarbase 8.49E-09 4.60E-05 1.98E-08 1.82E-07 21 349 "ATAT1,ADAR,F3,ADARB2,SESN3,CAPRIN2,SALL3,SMOC1,CAMSAP2,TCF7L2,DDR2,PSD3,ZFYVE9,UBTF,BTF3L4,CSDE1,WIPF2,RAB5B,PLEKHB2,ARHGAP12,UEVLD" MicroRNA hsa-miR-195-5p:Functional MTI Functional MTI miRTarbase 8.58E-09 4.65E-05 2.00E-08 1.84E-07 29 639 "ADORA3,CCDC80,CAB39,BCL2L2,GANAB,BTRC,CYB561A3,TGFBR3,CDC42,TPM3,DLGAP3,CAMKV,NEGR1,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,CSDE1,PTPRD,PLEKHB2,RTN4,RET,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-6799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.73E-09 4.73E-05 2.03E-08 1.87E-07 30 679 "RTKN,ADAR,CCDC80,CLSTN1,SLC1A2,SLC2A5,DNAH17,KBTBD12,ZCCHC24,TTLL9,FXYD6,DDR1,BEST3,SCRG1,PFKFB3,BTF3L4,FAT3,MFSD4A,DOCK7,NOS1AP,KIAA0513,DPYSL5,TOMM20,SNX27,DNAH9,RAB5B,PLEKHB2,PARP11,PHC2,ABI2" MicroRNA "CCCAGAG,MIR-326:MSigDB" "CCCAGAG,MIR-326:MSigDB" MSigDB 8.79E-09 4.76E-05 2.05E-08 1.88E-07 14 147 "KCNIP2,ITSN1,PPM1E,ST3GAL3,SLC8A2,SNCB,ATP2B2,ARPP21,CACNA1E,PPP3CB,RIMS4,KIAA0513,COPS7A,BSDC1" MicroRNA hsa-miR-220a:mirSVR_lowEffct hsa-miR-220a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.84E-09 4.78E-05 2.06E-08 1.89E-07 28 601 "ACTN2,ARID1A,RTKN,CLIP1,ASIC4,ST8SIA1,SLC1A7,MADD,EIF4G3,WDTC1,GAD2,DCLK2,TBX15,PCDHGA3,CYB561A3,TJP1,PADI2,PCDH9,CDH10,PRMT8,PFKFB3,CHRM1,TJP2,FAM181B,PPP2R5C,PRKACB,FGFR1OP2,HP1BP3" MicroRNA hsa-miR-519c-3p:Functional MTI Functional MTI miRTarbase 8.93E-09 4.83E-05 2.08E-08 1.91E-07 21 350 "ATAT1,ADAR,F3,ADARB2,SESN3,CAPRIN2,SALL3,SMOC1,CAMSAP2,TCF7L2,DDR2,PSD3,ZFYVE9,UBTF,BTF3L4,CSDE1,WIPF2,RAB5B,PLEKHB2,ARHGAP12,UEVLD" MicroRNA hsa-miR-18a-3p:Functional MTI Functional MTI miRTarbase 8.93E-09 4.83E-05 2.08E-08 1.91E-07 21 350 "DPF1,ACLY,ARID1A,F3,PPFIA1,CACHD1,ATM,GART,NCDN,PHLDB1,ARHGEF7,GNAS,WWC1,MFSD2A,ACOT7,HMGB1,CAMKV,UBTF,FADS2,MED24,BSCL2" MicroRNA hsa-miR-630:PITA hsa-miR-630:PITA_TOP PITA 9.02E-09 4.88E-05 2.10E-08 1.92E-07 16 199 "GPR158,FOXG1,ANK3,APBA2,SLITRK3,CADPS,SALL3,NPAS3,LMO3,GRIA2,PCDH9,RBFOX2,ITGAV,PID1,RASGRF1,PAK5" MicroRNA hsa-miR-140-3p.2:TargetScan hsa-miR-140-3p.2 TargetScan 1.04E-08 5.61E-05 2.41E-08 2.21E-07 21 353 "RTN3,CDC7,GPR158,SCN3A,HPCAL4,FOXG1,ANK2,LRRC4C,NRG3,ATP2B2,GAD2,FXYD6,PCDH8,RBFOX2,PACSIN1,NCAN,PROX1,PTCH1,KIF2A,GOPC,EN2" MicroRNA hsa-miR-517a:mirSVR_highEffct hsa-miR-517a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-08 5.63E-05 2.42E-08 2.22E-07 16 201 "SYNDIG1,SLITRK1,SNX32,ERICH3,MIER1,SLCO1A2,SMARCE1,NFIA,WWC1,TJP1,HPS5,TNS1,LRRTM3,OLFM3,SMG7,CBLN2" MicroRNA hsa-miR-942-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.04E-08 5.63E-05 2.42E-08 2.22E-07 16 201 "FAM43B,MDM4,GALNT13,NLGN4X,ANK1,ASCL1,TMEM151A,ATP1A3,DKK3,GFRA1,GJB1,ZNF638,ACSL6,TNS1,PTGDR2,ELAVL3" MicroRNA hsa-miR-874:PITA hsa-miR-874:PITA_TOP PITA 1.05E-08 5.67E-05 2.43E-08 2.23E-07 14 149 "DSCAML1,SORCS1,MEGF11,AJAP1,ADGRL3,PSD3,NMT2,CABP1,POU3F2,SNX27,PLEKHB2,ATG16L1,RAP1GAP,ARHGAP12" MicroRNA hsa-miR-7111-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-08 5.83E-05 2.50E-08 2.29E-07 18 259 "EMID1,WAC,ANK1,PKNOX2,RAP1GAP2,NFASC,NDUFA5,NRGN,CAMK2A,DLGAP3,UBTF,CCSER2,SPATA6,CRMP1,PTPA,BDNF-AS,PHC2,EFNA3" MicroRNA hsa-miR-598:mirSVR_highEffct hsa-miR-598:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-08 5.83E-05 2.50E-08 2.29E-07 18 259 "MAP6,ARID1A,SLC44A5,NLGN1,ALDH1L1,GPM6B,CRB1,RBFOX2,ZMYND8,CASC2,FAM181B,CNRIP1,TOX,SPIRE1,CADM2,PTPRZ1,RFX4,GPR61" MicroRNA hsa-miR-373-3p:Functional MTI Functional MTI miRTarbase 1.10E-08 5.95E-05 2.55E-08 2.34E-07 26 531 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,LEFTY2,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,RAD52,PHC2,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-514:PITA hsa-miR-514:PITA_TOP PITA 1.10E-08 5.97E-05 2.56E-08 2.34E-07 15 175 "EPS8,RTN1,SCN3A,SESN3,ARFGAP2,SON,TCF12,GRIA2,REPS2,CADM1,BTF3L4,LRRTM3,PTPRZ1,SH3GLB1,BAALC" MicroRNA hsa-miR-548b-3p:PITA hsa-miR-548b-3p:PITA_TOP PITA 1.10E-08 5.98E-05 2.56E-08 2.35E-07 17 230 "PLEKHG5,SLITRK1,LRRTM4,SEMA6A,MAGI3,CACHD1,BRINP2,RCOR3,NPAS3,TPD52,HMGB1,MED1,RIMS4,LRRTM3,RAB5B,TMEM255A,RFX5" MicroRNA hsa-miR-10a:mirSVR_highEffct hsa-miR-10a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.13E-08 6.12E-05 2.62E-08 2.40E-07 28 608 "ITSN1,CCDC88A,SLCO1A2,SPHKAP,RCOR3,SON,SOX1,NEK6,GART,NPAS3,GLS,TPD52,CADM1,CNTN1,POU3F2,PPP3CB,RAB39A,IGSF1,PLPPR5,SYNC,HP1BP3,CEP170,MAGI2,KCNA6,KCNK2,DSCAM,RPRD1A,ARHGAP12" MicroRNA hsa-miR-581:PITA hsa-miR-581:PITA_TOP PITA 1.14E-08 6.18E-05 2.64E-08 2.42E-07 14 150 "LGR4,SORCS1,LRRC7,TMEM151A,SON,CACNA1A,VSTM2A,PCDH9,TENM4,KCNA1,PTPRD,DSCAM,FAM135B,RCAN2" MicroRNA hsa-miR-5698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-08 6.44E-05 2.75E-08 2.52E-07 25 496 "EMID1,ADCY2,WAC,ANK1,PKNOX2,RAP1GAP2,NFASC,NDUFA5,WWC1,CNDP1,VWC2,NRGN,CAMK2A,DLGAP3,UBTF,CCSER2,MEAF6,SPATA6,CRMP1,PTPA,BDNF-AS,GNE,ZYG11B,EFNA3,UEVLD" MicroRNA hsa-miR-130b-3p:Functional MTI Functional MTI miRTarbase 1.19E-08 6.46E-05 2.76E-08 2.53E-07 27 571 "ADAR,F3,ADARB2,CLIP1,SYBU,CAPRIN2,SON,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZEB1,PDE3B,ZFYVE9,BTF3L4,FAT3,ACBD5,LRP8,CEP170,WIPF2,RAB5B,GOPC,SFXN5,ARHGAP12" MicroRNA hsa-miR-199b-3p:TargetScan hsa-miR-199b-3p TargetScan 1.20E-08 6.49E-05 2.77E-08 2.54E-07 21 356 "ADD3,BCAR3,CNIH2,CCDC88A,ASTN1,PHYHIPL,EMC1,LMO3,NFIA,GNAS,EML4,CECR2,DDR2,REPS2,PDE4B,CELF5,FAT3,RNF14,MAPK8,PTPRZ1,DTNA" MicroRNA hsa-miR-199a-3p:TargetScan hsa-miR-199a-3p TargetScan 1.20E-08 6.49E-05 2.77E-08 2.54E-07 21 356 "ADD3,BCAR3,CNIH2,CCDC88A,ASTN1,PHYHIPL,EMC1,LMO3,NFIA,GNAS,EML4,CECR2,DDR2,REPS2,PDE4B,CELF5,FAT3,RNF14,MAPK8,PTPRZ1,DTNA" MicroRNA hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 1.20E-08 6.52E-05 2.78E-08 2.55E-07 24 460 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,NFIA,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 1.20E-08 6.52E-05 2.78E-08 2.55E-07 24 460 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,LEFTY2,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-1261:PITA hsa-miR-1261:PITA_TOP PITA 1.26E-08 6.80E-05 2.90E-08 2.66E-07 17 232 "TMEM74,ACTN2,EYA1,WAC,AQP4,CCDC88A,ATP2B2,AHCYL1,ERBIN,SYT4,PCDH9,FNDC5,NEGR1,NSD2,PTPRD,PTPRZ1,CBLN2" MicroRNA hsa-miR-6892-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-08 6.95E-05 2.96E-08 2.72E-07 16 204 "ACTN2,ASIC4,DKK3,ZNF638,NODAL,TMEM151B,GRID1,OLR1,ZDHHC22,CDH8,GPR37L1,PFKFB3,RGS6,DPYSL5,ST8SIA3,VANGL2" MicroRNA hsa-miR-518b:mirSVR_lowEffct hsa-miR-518b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-08 6.97E-05 2.97E-08 2.72E-07 25 498 "EXTL1,ACTN2,WLS,PLEKHG5,FOXRED2,LRRC7,MOBP,BCAN,SHANK2,SCG3,SON,NKX6-2,GFAP,ADHFE1,ZEB1,NRGN,GRIA1,LINC00839,TPM3,BEST3,NRXN1,PIK3CD,SULT4A1,SIRPA,SRGAP3" MicroRNA hsa-miR-362-3p:Functional MTI Functional MTI miRTarbase 1.33E-08 7.19E-05 3.06E-08 2.81E-07 26 536 "CSMD2,ADCYAP1R1,PNMA8B,CHST15,MOBP,SGIP1,JAKMIP3,ATP1A3,WDTC1,INKA2,AJAP1,EML4,GRIK3,DAAM2,PRMT8,UBTF,SF1,CRLS1,NOS1AP,RIMS3,PTCH1,LRP8,MED24,KCNA4,KCNK1,FGFBP3" MicroRNA hsa-miR-615-5p:PITA hsa-miR-615-5p:PITA_TOP PITA 1.34E-08 7.25E-05 3.08E-08 2.83E-07 10 66 "SEMA6A,NCAM1,CDK5R2,FBXL16,CABP1,PPP2R5C,RGS6,RIMS4,MAPK10,DNAJC6" MicroRNA "GTGGTGA,MIR-197:MSigDB" "GTGGTGA,MIR-197:MSigDB" MSigDB 1.34E-08 7.25E-05 3.08E-08 2.83E-07 10 66 "KCNIP2,ANK2,PPM1E,NLGN1,ADGRL3,GRIA2,GRIN1,CTNND1,TTLL7,PIANP" MicroRNA hsa-miR-548s:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-08 7.27E-05 3.09E-08 2.84E-07 23 427 "MAG,MAPT,RTKN,FOXRED2,HOGA1,GOLGA7B,MAGI3,GPAM,URGCP,ATP1A2,SOX5,KIF1B,LUZP2,WWC1,ADAMTS8,TPM3,ATCAY,MAPK8,FGFR1OP2,RGMA,BLOC1S6,RABGAP1L,SIDT2" MicroRNA "ACCATTT,MIR-522:MSigDB" "ACCATTT,MIR-522:MSigDB" MSigDB 1.35E-08 7.32E-05 3.11E-08 2.85E-07 14 152 "PPM1E,ARHGAP5,CSPG5,PHYHIPL,WDTC1,NMNAT2,LMO3,GPM6B,ZNF384,HNRNPK,TLX1,DOCK7,CSDE1,ZC3H11A" MicroRNA hsa-miR-4768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-08 7.45E-05 3.17E-08 2.90E-07 29 653 "SDE2,ARID1A,SFMBT2,SLC2A5,KBTBD12,ATM,GJB1,FAM168A,ZNF638,LUZP2,GNAS,GNG3,BTRC,PTBP2,NUCB1,PSD3,TMEM9,TPM3,GPR37L1,LRTM2,PIK3CD,FTO,PACSIN1,MFSD4A,PTPA,KIAA0513,SNX27,GNE,SYT15" MicroRNA hsa-miR-3193:mirSVR_lowEffct hsa-miR-3193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-08 7.54E-05 3.20E-08 2.94E-07 22 393 "MEG3,WLS,SLITRK1,NLGN4X,FCGR1A,MT3,B3GALT2,NMNAT2,NFASC,UNC5D,KCNK10,ARHGAP19,POU3F2,FAM131B,SIRPA,COPS7A,NTM,NKAIN1,OLIG1,FAM66C,DTNA,RNF220" MicroRNA hsa-miR-329-3p:Functional MTI Functional MTI miRTarbase 1.43E-08 7.74E-05 3.29E-08 3.01E-07 26 538 "CSMD2,ADCYAP1R1,PNMA8B,CHST15,MOBP,SGIP1,JAKMIP3,ATP1A3,WDTC1,INKA2,AJAP1,EML4,GRIK3,DAAM2,PRMT8,UBTF,SF1,CRLS1,NOS1AP,RIMS3,PTCH1,LRP8,MED24,KCNA4,KCNK1,FGFBP3" MicroRNA hsa-miR-6873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-08 7.98E-05 3.39E-08 3.11E-07 16 206 "MAG,RPH3A,CCDC88A,GFRA1,GNG3,DDR1,HAP1,TPM3,TMPRSS5,CHRNB2,PTPA,PMEPA1,NKAIN1,RAB5B,ST8SIA3,EN2" MicroRNA hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 1.48E-08 8.01E-05 3.40E-08 3.12E-07 24 465 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,LEFTY2,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA "CTCTAGA,MIR-518F:MSigDB" "CTCTAGA,MIR-518F:MSigDB" MSigDB 1.49E-08 8.06E-05 3.41E-08 3.13E-07 9 50 "KCNIP2,SORCS1,FHL1,ANK2,JPH4,BCL2L2,PIK3CD,BRINP3,SLC4A10" MicroRNA "CTCTAGA,MIR-526A:MSigDB" "CTCTAGA,MIR-526A:MSigDB" MSigDB 1.49E-08 8.06E-05 3.41E-08 3.13E-07 9 50 "KCNIP2,SORCS1,FHL1,ANK2,JPH4,BCL2L2,PIK3CD,BRINP3,SLC4A10" MicroRNA "CTCTAGA,MIR-526C:MSigDB" "CTCTAGA,MIR-526C:MSigDB" MSigDB 1.49E-08 8.06E-05 3.41E-08 3.13E-07 9 50 "KCNIP2,SORCS1,FHL1,ANK2,JPH4,BCL2L2,PIK3CD,BRINP3,SLC4A10" MicroRNA hsa-miR-486-5p:PITA hsa-miR-486-5p:PITA_TOP PITA 1.50E-08 8.14E-05 3.45E-08 3.16E-07 13 129 "ARID1A,SORCS1,NLGN1,ARHGAP5,CSPG5,RCOR3,SMOC1,CADM1,NSD2,FAT3,PPP3CB,KCNA1,RBM12" MicroRNA hsa-miR-3176:mirSVR_highEffct hsa-miR-3176:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-08 8.66E-05 3.65E-08 3.35E-07 26 541 "CLIP1,SORCS1,SNX32,FGF14,UNC79,RUFY2,CGREF1,SON,NPAS3,ERBIN,SYT4,PSRC1,ADGRL3,MAEL,CDH8,PDE3B,CADM1,FEZ1,CTNND2,PRDM2,RABGAP1L,RAD52,DPP6,ATG16L1,BSCL2,UEVLD" MicroRNA hsa-miR-518d-3p:mirSVR_lowEffct hsa-miR-518d-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-08 8.66E-05 3.65E-08 3.35E-07 26 541 "EXTL1,ACTN2,WLS,PLEKHG5,FOXRED2,LRRC7,MOBP,BCAN,ARHGAP5,SHANK2,SCG3,SON,GFAP,ADHFE1,ZEB1,NRGN,LINC00839,TPM3,BEST3,NRXN1,SULT4A1,SLC25A27,SIRPA,SRGAP3,KCNJ11,LMO1" MicroRNA "CTACCTC,LET-7B:MSigDB" "CTACCTC,LET-7B:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,MIR-98:MSigDB" "CTACCTC,MIR-98:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7C:MSigDB" "CTACCTC,LET-7C:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7G:MSigDB" "CTACCTC,LET-7G:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7F:MSigDB" "CTACCTC,LET-7F:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7A:MSigDB" "CTACCTC,LET-7A:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7I:MSigDB" "CTACCTC,LET-7I:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7D:MSigDB" "CTACCTC,LET-7D:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA "CTACCTC,LET-7E:MSigDB" "CTACCTC,LET-7E:MSigDB" MSigDB 1.60E-08 8.67E-05 3.65E-08 3.35E-07 21 362 "LGR4,SCN4B,GAS7,SLC8A2,DKK3,KIF21B,ADAM15,NFASC,CLASP2,ACSL6,ADAMTS8,TNFRSF1B,SLC25A27,PRRX1,OSBPL3,IGSF1,MASP1,PRDM2,BLOC1S6,SLC25A18,VANGL2" MicroRNA hsa-miR-4775:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-08 8.79E-05 3.70E-08 3.39E-07 19 297 "RTN3,WAC,SGIP1,SLC7A14,KIAA1614,PALLD,DKK3,PCDH11X,PTBP2,NUCB1,GRIK4,TUB,NSD2,KCNT2,RIMS4,MAPK8,CEP170,SSPN,EPB41L1" MicroRNA hsa-miR-873-5p.1:TargetScan hsa-miR-873-5p.1 TargetScan 1.63E-08 8.81E-05 3.71E-08 3.40E-07 18 266 "ABAT,RTN3,HPCAL4,APC,SCN3B,GOLGB1,PSD3,DAAM2,PADI2,HNRNPK,DLGAP3,CADM1,COL9A2,MED1,JAKMIP2,RASGRF1,PIANP,ABI2" MicroRNA hsa-miR-194-5p:TargetScan hsa-miR-194-5p TargetScan 1.70E-08 9.18E-05 3.86E-08 3.54E-07 20 330 "ACHE,ELMOD1,ITSN1,LRRC4C,ARHGAP5,GJB1,MYRF,CAMK2G,RFFL,OPCML,CADM1,BTF3L4,NXPH1,PLD5,PMEPA1,CEP170,PTPRD,KCNJ11,JMJD1C,ARHGAP12" MicroRNA hsa-miR-638:mirSVR_lowEffct hsa-miR-638:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-08 9.44E-05 3.97E-08 3.64E-07 22 398 "ATAT1,CGREF1,CAPRIN2,RCOR3,ADAM15,NFASC,GLS,CAMTA1,MMD2,NUDT21,TNFRSF1B,CCDC136,PNKD,PRKAB2,FMN2,JAKMIP2,RAB3IL1,DNM2,NUP214,RGS7,RERGL,ELAVL4" MicroRNA hsa-miR-1225-5p:PITA hsa-miR-1225-5p:PITA_TOP PITA 1.79E-08 9.67E-05 4.07E-08 3.73E-07 11 87 "CSMD3,SLITRK1,BCL2L2,GRIA4,KCNA1,PTPRD,KCNK1,KCNMA1,RAB5B,L1CAM,INSYN2" MicroRNA hsa-miR-193a-3p:mirSVR_highEffct hsa-miR-193a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.81E-08 9.81E-05 4.12E-08 3.78E-07 24 470 "RABEPK,MSRA,CCDC88A,SCG3,SON,CAB39,GART,ERBIN,SEPT3,CAMTA1,BTRC,PSRC1,TCF7L2,CDH8,PDE1A,ZMYND8,CADM1,MED1,PPP2R5C,MICAL2,CTNND2,MAPK10,ZC3H11A,ZNF248" MicroRNA "AAAGGGA,MIR-211:MSigDB" "AAAGGGA,MIR-211:MSigDB" MSigDB 2.07E-08 1.12E-04 4.70E-08 4.31E-07 16 211 "TTYH1,SGIP1,ZCCHC24,SMOC1,DCAF5,GPM6A,TCF12,ZFP91,CDC42,PCDH9,PRRX1,POU3F2,PRDM2,DNM2,SEC61A2,ELAVL3" MicroRNA "AAAGGGA,MIR-204:MSigDB" "AAAGGGA,MIR-204:MSigDB" MSigDB 2.07E-08 1.12E-04 4.70E-08 4.31E-07 16 211 "TTYH1,SGIP1,ZCCHC24,SMOC1,DCAF5,GPM6A,TCF12,ZFP91,CDC42,PCDH9,PRRX1,POU3F2,PRDM2,DNM2,SEC61A2,ELAVL3" MicroRNA "ACAACTT,MIR-382:MSigDB" "ACAACTT,MIR-382:MSigDB" MSigDB 2.08E-08 1.13E-04 4.73E-08 4.34E-07 10 69 "NDRG2,SORCS3,EIF4G3,NFIA,CAMTA1,P2RX7,NEGR1,SYNC,SLC17A6,EN2" MicroRNA hsa-miR-1205:mirSVR_highEffct hsa-miR-1205:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.14E-08 1.16E-04 4.86E-08 4.46E-07 31 748 "ATAT1,TOMM40L,FHL1,MOG,AMPH,ANK2,CNIH2,ITSN1,SH3GL2,ZCCHC17,DKK3,MYT1L,B3GALT2,TTLL9,DNER,ARHGEF7,CACNA1A,AKNA,INA,P2RX7,PDE3B,CHI3L2,BEST1,NXPH1,RAB39A,KLK6,SMG7,SRGAP3,DNAH9,TTLL7,ABI2" MicroRNA hsa-miR-194:PITA hsa-miR-194:PITA_TOP PITA 2.17E-08 1.17E-04 4.92E-08 4.51E-07 18 271 "ACHE,ITSN1,APC,NTNG1,ARHGAP5,SOX5,CLASP2,NEUROD1,SYT4,CAMSAP2,LGI1,SERPINE2,BTF3L4,NXPH1,PMEPA1,PTPRD,PTPRZ1,ELAVL3" MicroRNA hsa-miR-921:PITA hsa-miR-921:PITA_TOP PITA 2.20E-08 1.19E-04 4.98E-08 4.57E-07 12 110 "ADD3,SOX6,CCDC88A,ZCCHC24,LMO3,ADGRL3,RBFOX2,CADM1,BTF3L4,POU3F2,NRSN1,VANGL2" MicroRNA hsa-miR-1973:mirSVR_highEffct hsa-miR-1973:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.20E-08 1.19E-04 4.98E-08 4.57E-07 12 110 "LDLRAD3,HOGA1,BCAS1,TBX15,GRIA4,PCDH9,PRMT8,ZMYND8,CASC2,VCAN,PSMD13,MAGI2" MicroRNA hsa-miR-665:PITA hsa-miR-665:PITA_TOP PITA 2.21E-08 1.20E-04 5.01E-08 4.60E-07 16 212 "SDE2,TOMM40L,AMPH,KIF21B,NCAM1,AJAP1,NRGN,FNDC5,SF1,RIMS4,CTNND1,HP1BP3,KCNN3,EFNA3,LMO1,RCAN2" MicroRNA hsa-miR-1307:mirSVR_lowEffct hsa-miR-1307:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-08 1.26E-04 5.28E-08 4.85E-07 15 185 "TOMM40L,NSG2,C11orf87,AJAP1,DCLK2,ADGRL3,NRGN,GRIA1,GRIA2,PLXNB3,C11orf49,CABP1,PPP3CB,WBP1L,STMN4" MicroRNA hsa-miR-323b-3p:mirSVR_highEffct hsa-miR-323b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-08 1.27E-04 5.30E-08 4.86E-07 27 590 "ACER3,SORCS1,LINC00461,MOBP,FOXM1,NTNG1,PAAF1,ERBIN,C1QC,MAEL,TPD52,ZMYND8,CADM1,FTO,MEAF6,BTF3L4,CHD1L,PPP3CB,OSBPL3,VCAN,ZNF385B,ITGAV,KCNA2,KCNMA1,DBX2,ABCC9,ZYG11B" MicroRNA hsa-miR-4329:mirSVR_highEffct hsa-miR-4329:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-08 1.27E-04 5.30E-08 4.86E-07 27 590 "MBP,RCSD1,ARID1A,FABP7,LRRC7,ASIC4,MOG,ITSN1,MAGI3,CGREF1,DDX25,PHYHIPL,DKK3,B3GALT2,B4GALNT1,IDI2-AS1,CDH8,BEST3,CADM1,PMP2,WBP1L,DNAJC6,LRP8,RFX5,FGFBP3,ARHGAP12,RCAN2" MicroRNA hsa-miR-1914*:mirSVR_highEffct hsa-miR-1914*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-08 1.30E-04 5.42E-08 4.97E-07 24 477 "CDHR1,FCGR1A,ANK2,CCDC80,BCAS1,ZNF365,LRRC55,CCDC88A,TMEM108,SOX5,JPH4,B4GALNT1,FAM168A,GPM6A,LRIT2,GRIA4,TMEM25,CADM1,MICAL2,PSMD13,RAB5B,JMJD1C,YY1AP1,BAALC" MicroRNA hsa-miR-4284:mirSVR_highEffct hsa-miR-4284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-08 1.30E-04 5.42E-08 4.97E-07 24 477 "RXRG,GPR158,FOXM1,MAGI3,RUFY2,NEK6,NASP,GNAS,SYT6,GRIA2,ATP13A2,MFSD2A,PDE3B,MICAL2,MASP1,GON4L,PRDM2,MAGI2,PTPRO,KCNMA1,RAD52,SLC25A18,ZNF248,UEVLD" MicroRNA hsa-miR-628-5p:PITA hsa-miR-628-5p:PITA_TOP PITA 2.40E-08 1.30E-04 5.44E-08 4.99E-07 14 159 "ARID1A,SLITRK1,SCN3A,ANK3,RCOR3,PHYHIPL,NFIA,CACNB2,PTBP2,CAMK2G,GRIN1,CDH10,MED1,SNX27" MicroRNA hsa-miR-1291:mirSVR_highEffct hsa-miR-1291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-08 1.32E-04 5.52E-08 5.06E-07 21 371 "LGR4,GALNT13,TESK2,SGIP1,NTNG1,ZNF365,SON,ARPP21,ZNF638,GPM6A,SYT6,GRIA2,TF,CPT1C,OPALIN,MED1,NRSN1,LRRTM3,PTAFR,RALGDS,VWA5A" MicroRNA hsa-miR-6833-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-08 1.37E-04 5.69E-08 5.22E-07 20 338 "ACER3,TUBB4A,NLGN4X,DGKD,ASCL1,IGSF9B,ATP1A3,MYBPC1,GJB1,GPR26,FBXL16,P2RX7,TNS1,CDH8,TLX1,GDAP1L1,NEGR1,CADM2,NAV2,ELAVL3" MicroRNA hsa-miR-4768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-08 1.37E-04 5.69E-08 5.22E-07 20 338 "ACER3,TUBB4A,NLGN4X,DGKD,ASCL1,IGSF9B,ATP1A3,MYBPC1,GJB1,GPR26,FBXL16,P2RX7,TNS1,CDH8,TLX1,GDAP1L1,NEGR1,CADM2,NAV2,ELAVL3" MicroRNA hsa-miR-324-3p:Functional MTI Functional MTI miRTarbase 2.52E-08 1.37E-04 5.69E-08 5.22E-07 20 338 "ACLY,RBM10,ARID1A,PPFIA1,SON,GNAS,WWC1,MFSD2A,TJP1,KCNK10,MAGI1,ACOT7,HMGB1,CAMKV,FADS2,CTNND1,PUM1,MED24,PLEKHB2,BSCL2" MicroRNA hsa-miR-767-3p:PITA hsa-miR-767-3p:PITA_TOP PITA 2.52E-08 1.37E-04 5.69E-08 5.22E-07 16 214 "SYT9,CNIH2,DOCK10,TACC2,MYT1L,BCL2L2,CAMTA1,CECR2,TOX,PTCH1,DNAJC6,KCNA4,KIF2A,TMEM255A,SLC6A15,RBM12" MicroRNA hsa-miR-573:PITA hsa-miR-573:PITA_TOP PITA 2.52E-08 1.37E-04 5.69E-08 5.22E-07 16 214 "GPR158,PKP4,SLITRK3,SOX5,KIF1B,ERBIN,CAMSAP2,UNC5D,GUCY1A1,CDH10,PKN2,PROX1,PTPRD,PID1,TMEM255A,JMJD1C" MicroRNA "CAATGCA,MIR-33:MSigDB" "CAATGCA,MIR-33:MSigDB" MSigDB 2.56E-08 1.39E-04 5.78E-08 5.30E-07 11 90 "SLC25A25,SLITRK3,SHANK2,B3GALT2,SALL3,CAMK2G,GPR88,LGI1,DPYSL5,KCNMA1,EN2" MicroRNA hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA_TOP PITA 2.69E-08 1.46E-04 6.07E-08 5.57E-07 16 215 "NPAS3,SYT4,CAMTA1,BTRC,PTBP2,EML4,OPCML,CADM1,CAMKV,CRMP1,CHD5,SRGAP3,KCNMA1,WIPF2,VANGL2,RBM12" MicroRNA hsa-miR-329:PITA hsa-miR-329:PITA_TOP PITA 2.69E-08 1.46E-04 6.07E-08 5.57E-07 16 215 "NPAS3,SYT4,CAMTA1,BTRC,PTBP2,EML4,OPCML,CADM1,CAMKV,CRMP1,CHD5,SRGAP3,KCNMA1,WIPF2,VANGL2,RBM12" MicroRNA hsa-miR-665:mirSVR_highEffct hsa-miR-665:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-08 1.48E-04 6.16E-08 5.66E-07 28 634 "DUSP27,MEG3,MDM4,NDRG2,AMPH,NTNG1,ZCCHC17,PKNOX2,JPH4,TTLL9,ASTN2,SEMA4A,NODAL,GRIA4,VWCE,MFSD2A,PC,MAGI1,ADGRG1,GDAP1L1,CHD1L,OSBPL3,NRSN1,HP1BP3,KCNN3,DPP6,RPRD1A,SLC4A10" MicroRNA "AGTCTTA,MIR-499:MSigDB" "AGTCTTA,MIR-499:MSigDB" MSigDB 2.76E-08 1.50E-04 6.22E-08 5.71E-07 10 71 "TESK2,SOX6,SOX5,AZIN2,PTBP2,EML4,FAM131B,NAV2,RNF220,ARHGAP12" MicroRNA hsa-miR-1287:PITA hsa-miR-1287:PITA_TOP PITA 2.98E-08 1.61E-04 6.70E-08 6.15E-07 12 113 "SYT9,SH3GL2,SLC7A14,GPM6A,GRIA4,TPM3,HEPACAM,KIAA1755,PLD5,MAPK10,OCIAD1,PAK5" MicroRNA hsa-miR-6818-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-08 1.65E-04 6.86E-08 6.29E-07 14 162 "FGF14,SEMA6A,GFRA1,ZEB1,KCNK10,TNR,SLC22A6,NRXN1,PPP3CB,NCAN,JAKMIP2,BLOC1S6,TTLL7,EN2" MicroRNA hsa-miR-595:PITA hsa-miR-595:PITA_TOP PITA 3.07E-08 1.66E-04 6.89E-08 6.32E-07 16 217 "CSMD3,WAC,BCAR3,SORCS3,NCAM1,NFIA,GRIA2,GPR88,REPS2,LGI1,PRRX1,PLD5,PUM1,RAP1GAP,RGS7,RBM12" MicroRNA hsa-miR-526b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-08 1.71E-04 7.10E-08 6.51E-07 17 247 "FAM43B,AMER2,FGF1,SLC30A10,SGIP1,CCDC80,RCOR3,CAB39,ASTN2,ACSL6,GPR26,ZFYVE9,MEAF6,CADM2,C12orf4,SH3GLB1,ELAVL4" MicroRNA hsa-miR-423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.21E-08 1.74E-04 7.22E-08 6.62E-07 20 343 "MDM4,PNMA8B,CLSTN1,SLC2A5,ASPH,NKX6-2,NFASC,GJB1,AJAP1,B4GALNT4,GRID1,OLR1,CD81,PFKFB3,NOS1AP,COPS7A,CSDE1,WIPF2,ATN1,EPB41" MicroRNA hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-08 1.75E-04 7.27E-08 6.67E-07 23 448 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-3133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.33E-08 1.80E-04 7.47E-08 6.86E-07 15 190 "TTYH1,SDE2,ACER3,ATM,SON,GJB1,GPR26,RBFOX2,SEZ6L,SF1,RBPJ,RIMS3,BLOC1S6,ABCC9,RGR" MicroRNA hsa-miR-484:Functional MTI Functional MTI miRTarbase 3.34E-08 1.81E-04 7.49E-08 6.87E-07 34 891 "ACLY,RTN3,ARID1A,ADAR,WAC,TOMM40L,KIAA1109,GPAM,URGCP,MTR,ATP1A2,KIF21B,ZSWIM8,GART,NASP,GANAB,ZEB1,GPR26,CECR2,NUCB1,GRIA4,AIFM1,CDC42,HNRNPK,CADM1,UBTF,CCDC136,RNF14,SPIRE1,PMEPA1,BLOC1S6,ATN1,RFX5,FGFBP3" MicroRNA hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 3.37E-08 1.83E-04 7.56E-08 6.94E-07 23 449 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-122*:mirSVR_lowEffct hsa-miR-122*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.50E-08 1.90E-04 7.86E-08 7.21E-07 22 414 "ADARB2,SLITRK1,SESN3,BCAS1,PAAF1,AQP4,PKNOX2,SLC14A1,MMD2,PTBP2,DAAM2,DCLK1,PLD5,FAM131B,ZBTB16,CADM2,PRTFDC1,KCNA4,KCNA6,DTNA,ARHGEF10L,TMEM100" MicroRNA hsa-miR-518a-3p:mirSVR_lowEffct hsa-miR-518a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.54E-08 1.92E-04 7.93E-08 7.27E-07 26 563 "EXTL1,ACTN2,WLS,PLEKHG5,FOXRED2,SCN3A,LRRC7,MOBP,BCAN,ARHGAP5,SHANK2,SON,GFAP,ADHFE1,ZEB1,NRGN,LINC00839,TPM3,BEST3,NRXN1,SULT4A1,SLC25A27,SIRPA,SRGAP3,KCNJ11,LMO1" MicroRNA hsa-miR-10b:mirSVR_highEffct hsa-miR-10b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.54E-08 1.92E-04 7.93E-08 7.27E-07 26 563 "ITSN1,CCDC88A,SLCO1A2,SPHKAP,SON,SOX1,NEK6,GART,NPAS3,GLS,CADM1,CNTN1,POU3F2,PPP3CB,RAB39A,IGSF1,PLPPR5,SYNC,HP1BP3,CEP170,KCNA6,KCNK2,DSCAM,ZYG11B,RPRD1A,ARHGAP12" MicroRNA hsa-miR-489:PITA hsa-miR-489:PITA_TOP PITA 3.83E-08 2.07E-04 8.57E-08 7.86E-07 15 192 "EYA1,ADD3,LRRC7,SEMA6A,PPM1E,MAGI3,ST3GAL3,ATP2B2,ATF7,ZMYND8,MED1,DNAJC6,CADM2,MAGI2,PAK5" MicroRNA hsa-miR-331-3p:TargetScan hsa-miR-331-3p TargetScan 3.85E-08 2.08E-04 8.60E-08 7.89E-07 14 165 "CSMD2,CPLX2,GPR26,HAP1,GRIK3,DLGAP3,RIMS4,ECE2,PTPRD,C1orf109,RAB5B,FAM135B,PHC2,PLEKHO1" MicroRNA hsa-miR-1260:PITA hsa-miR-1260:PITA_TOP PITA 3.85E-08 2.08E-04 8.60E-08 7.89E-07 14 165 "CDC42BPA,NMNAT2,VAMP1,PTBP2,NUMA1,HNRNPK,NRXN2,CAMKV,STMN4,SRGAP3,DLG2,GPR61,ELAVL3,EPB41L1" MicroRNA hsa-miR-1249:mirSVR_lowEffct hsa-miR-1249:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-08 2.13E-04 8.80E-08 8.08E-07 19 314 "CEND1,FCGR1A,LINC00461,ANK3,NSG2,DCLK2,CAMSAP2,TMEM136,TCF7L2,GRIA4,GRIK4,GRIN1,TNR,MAGI1,HNRNPK,RGS6,FMN2,PHC2,FGFBP3" MicroRNA hsa-miR-520e:Functional MTI Functional MTI miRTarbase 3.96E-08 2.14E-04 8.85E-08 8.12E-07 23 453 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-1227:mirSVR_highEffct hsa-miR-1227:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.98E-08 2.15E-04 8.89E-08 8.15E-07 22 417 "TTYH1,ZFYVE27,CDC7,ANXA7,CACHD1,SHTN1,DKK3,ADAM15,DCLK2,PTBP2,GRIA2,P2RX7,SEZ6L,NEGR1,POU3F2,PNKD,PPP2R5C,RGS6,WBP1L,HP1BP3,JMJD1C,PHC2" MicroRNA hsa-miR-935:PITA hsa-miR-935:PITA_TOP PITA 3.98E-08 2.15E-04 8.89E-08 8.15E-07 18 282 "RTN3,LRRC7,APC,SLC1A2,CADPS,CAB39,PCDH11X,GPM6A,ACSL6,LGI1,FAT3,POU3F2,TOX,PTPRD,SRGAP3,ARNT2,DLG2,INSYN2" MicroRNA hsa-miR-596:PITA hsa-miR-596:PITA_TOP PITA 4.06E-08 2.20E-04 9.06E-08 8.31E-07 11 94 "GPR158,SEMA6A,CNIH2,SOX10,BCL2L2,NCDN,ZFP91,NEGR1,PHACTR3,SMG7,RAB3IL1" MicroRNA hsa-miR-1293:PITA hsa-miR-1293:PITA_TOP PITA 4.15E-08 2.25E-04 9.27E-08 8.51E-07 10 74 "SEMA6A,SLITRK3,PALLD,CLASP2,GANAB,VAMP1,VSTM2A,PSD,SRGAP3,KCNMA1" MicroRNA hsa-miR-92a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-08 2.26E-04 9.32E-08 8.55E-07 45 1407 "ACLY,RBM10,ARID1A,GRAMD1B,HOGA1,KIAA1109,RASA3,USP28,SESN3,CSPG5,ATM,CCDC181,AHCYL1,NEK6,KIF1B,NDUFA5,NCDN,GANAB,BTRC,NUCB1,RFFL,RBFOX2,TPM3,ZMYND8,HMGB1,PLEKHB1,CAMKV,PIK3CD,CCSER2,NSD2,RBPJ,IGSF1,MAPK8,EDRF1,TUBB2B,PMEPA1,HP1BP3,CSDE1,KCNC1,SV2A,WIPF2,DNM2,ATG16L1,TTLL7,VANGL2" MicroRNA hsa-miR-140-5p:PITA hsa-miR-140-5p:PITA_TOP PITA 4.20E-08 2.27E-04 9.36E-08 8.59E-07 18 283 "CSMD3,RTN1,ELMOD1,SH3GL2,CADM3,BCL2L2,ERBIN,PCDH11X,GPM6A,TJP1,FNDC5,CNTN1,PROX1,WBP1L,SNX27,DLG2,RBM12,EPB41L2" MicroRNA hsa-miR-6734-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.21E-08 2.28E-04 9.39E-08 8.62E-07 16 222 "ASIC4,PKNOX2,SLIT1,TMEM151A,PALLD,DKK3,INKA2,DDR1,TMEM151B,DAAM2,TNR,PADI2,SLC22A6,RIMS3,TMCC2,WIPF2" MicroRNA hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 4.29E-08 2.32E-04 9.55E-08 8.76E-07 23 455 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-520b:Functional MTI Functional MTI miRTarbase 4.29E-08 2.32E-04 9.55E-08 8.76E-07 23 455 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 4.29E-08 2.32E-04 9.55E-08 8.76E-07 23 455 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-382-3p:TargetScan hsa-miR-382-3p TargetScan 4.39E-08 2.38E-04 9.78E-08 8.97E-07 15 194 "CSMD3,NLGN1,AHCYL1,LMO3,ACSBG1,BTRC,AIFM1,PAX6,ARHGAP19,FTO,LRRTM3,DNAJC6,OCIAD1,KCNH1,KCNN3" MicroRNA hsa-miR-4286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.41E-08 2.39E-04 9.80E-08 8.99E-07 12 117 "CLIP1,NSG2,ATP1A3,CASTOR3,TBX15,CACNA1E,DIRAS1,TMEM151B,RIMS3,SIRPA,SEC61A2,EPB41L1" MicroRNA hsa-miR-1274b:PITA hsa-miR-1274b:PITA_TOP PITA 4.48E-08 2.42E-04 9.95E-08 9.13E-07 14 167 "SCN3A,LRRTM4,SGIP1,BRINP2,LHFPL4,NEUROD1,UNC5D,RBFOX2,HNRNPK,NRXN1,MED1,PTPRD,FAM135B,VANGL2" MicroRNA hsa-miR-365a-3p:TargetScan hsa-miR-365a-3p TargetScan 4.67E-08 2.53E-04 1.04E-07 9.52E-07 18 285 "EPS8,ADAR,ADD3,FGF1,ANK3,NFIA,GPM6A,PTBP2,PAX6,PCDH8,PDYN,HAPLN2,BEST3,BTF3L4,KCNA1,DLG3,PLEKHB2,DTNA" MicroRNA hsa-miR-365b-3p:TargetScan hsa-miR-365b-3p TargetScan 4.67E-08 2.53E-04 1.04E-07 9.52E-07 18 285 "EPS8,ADAR,ADD3,FGF1,ANK3,NFIA,GPM6A,PTBP2,PAX6,PCDH8,PDYN,HAPLN2,BEST3,BTF3L4,KCNA1,DLG3,PLEKHB2,DTNA" MicroRNA hsa-miR-193b:mirSVR_highEffct hsa-miR-193b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.70E-08 2.55E-04 1.04E-07 9.58E-07 22 421 "RABEPK,MSRA,SON,CAB39,GART,ERBIN,SEPT3,CAMTA1,BTRC,PSRC1,TCF7L2,CDH8,PDE1A,ZMYND8,CADM1,PPP2R5C,MICAL2,CTNND2,MAPK10,ZC3H11A,ZNF248,SEC61A2" MicroRNA hsa-miR-1911-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-08 2.57E-04 1.05E-07 9.65E-07 10 75 "TMEM156,DNAH17,GPR26,NUMA1,HMGB1,PTPA,MICAL2,NCAN,KCNH1,PHC2" MicroRNA hsa-miR-4723-5p:Functional MTI Functional MTI miRTarbase 4.75E-08 2.57E-04 1.05E-07 9.66E-07 17 254 "EMID1,WAC,ANK1,PKNOX2,RAP1GAP2,NFASC,NDUFA5,NRGN,CAMK2A,DLGAP3,UBTF,CCSER2,SPATA6,CRMP1,PTPA,BDNF-AS,EFNA3" MicroRNA "CACTTTG,MIR-520G:MSigDB" "CACTTTG,MIR-520G:MSigDB" MSigDB 4.77E-08 2.58E-04 1.06E-07 9.71E-07 16 224 "CSMD3,SLC1A2,SLC6A9,ATP2B2,ADGRB2,NPAS3,NELL1,NHLH1,ZFP91,PRRX1,NSD2,DPYSL5,CA10,MAGI2,DNM2,RFX4" MicroRNA "CACTTTG,MIR-520H:MSigDB" "CACTTTG,MIR-520H:MSigDB" MSigDB 4.77E-08 2.58E-04 1.06E-07 9.71E-07 16 224 "CSMD3,SLC1A2,SLC6A9,ATP2B2,ADGRB2,NPAS3,NELL1,NHLH1,ZFP91,PRRX1,NSD2,DPYSL5,CA10,MAGI2,DNM2,RFX4" MicroRNA "CCTGTGA,MIR-513:MSigDB" "CCTGTGA,MIR-513:MSigDB" MSigDB 4.85E-08 2.63E-04 1.07E-07 9.86E-07 12 118 "ACHE,EYA1,ADD3,PPM1E,NPAS3,TIE1,NSD2,CTNND1,CA10,KCND3,SRGAP3,NAV2" MicroRNA hsa-miR-377*:mirSVR_highEffct hsa-miR-377*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.01E-08 2.71E-04 1.11E-07 1.02E-06 26 573 "SERPINA3,ACER3,ASIC1,CDHR1,ANK1,DOCK10,GPAM,MIER1,MSR1,PKNOX2,CAPRIN2,FYN,MYT1L,NFASC,SYT4,POPDC3,VXN,CDC42,CDH10,SEZ6L,PDE2A,FAM181B,DPYSL5,CA10,PTHLH,FAM135B" MicroRNA hsa-miR-508-5p:PITA hsa-miR-508-5p:PITA_TOP PITA 5.03E-08 2.72E-04 1.11E-07 1.02E-06 15 196 "SDE2,RTN1,NCAM1,FAM168A,GLS,VAMP1,SYT6,PDE4B,OSBPL3,CTNND1,SV2A,TMCC2,DLG2,RGS7,ARHGAP12" MicroRNA hsa-miR-3667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.08E-08 2.75E-04 1.12E-07 1.03E-06 16 225 "ASIC4,SLIT1,C10orf105,PALLD,ACSBG1,DDR1,TMEM151B,DAAM2,TNR,PADI2,CDH8,TENM4,RIMS3,KCNJ4,WIPF2,PLEKHO1" MicroRNA hsa-miR-491-3p:PITA hsa-miR-491-3p:PITA_TOP PITA 5.19E-08 2.81E-04 1.15E-07 1.05E-06 18 287 "CLIP1,RTN1,ADD3,SEMA6A,MYT1L,B3GALT2,LHFPL4,PCDH11X,GRIA4,RBFOX2,TPM3,POU3F2,FMN2,LRRTM3,KCNA2,SLC17A6,ABI1,GOPC" MicroRNA hsa-miR-6870-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-08 2.88E-04 1.18E-07 1.08E-06 17 256 "EMID1,WAC,ANK1,PKNOX2,RAP1GAP2,NFASC,NDUFA5,NRGN,CAMK2A,DLGAP3,UBTF,CCSER2,SPATA6,CRMP1,PTPA,BDNF-AS,EFNA3" MicroRNA hsa-let-7e*:mirSVR_lowEffct hsa-let-7e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.32E-08 2.88E-04 1.18E-07 1.08E-06 17 256 "ACER3,EYA1,ATAT1,MDM4,MOBP,ANK3,FOLH1,PPM1E,CACHD1,ZNF638,LRIT2,GRIA2,ATRNL1,PRKACB,DPYSL5,CEP170,ZNF248" MicroRNA hsa-miR-299-5p:TargetScan hsa-miR-299-5p TargetScan 5.38E-08 2.91E-04 1.19E-07 1.09E-06 15 197 "RIMKLA,MIER1,ATP2B2,DDHD2,BTRC,CECR2,PCDH8,PCSK2,CCSER2,RBPJ,PROX1,DLG3,RFX5,FAM135B,RNF220" MicroRNA hsa-miR-629-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-08 2.91E-04 1.19E-07 1.09E-06 15 197 "GPR158,SLIT1,ZCCHC24,GANAB,ZNF638,ACSL6,NEURL1,ZDHHC22,PADI2,CDH8,NEGR1,CELF5,RGS6,ZNF248,EPB41L1" MicroRNA hsa-miR-6881-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.40E-08 2.92E-04 1.19E-07 1.09E-06 16 226 "SLC25A25,GRAMD1B,ASIC4,SLC7A14,ACSBG1,ZNF638,NUCB1,GRIK3,TGFBR3,PTGDR2,RBFOX2,HMGB1,SLC22A6,GDAP1L1,SMG7,TMCC2" MicroRNA hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 5.43E-08 2.94E-04 1.20E-07 1.10E-06 23 461 "FOXRED2,DRAXIN,CAPRIN2,SON,EMC1,BCL2L2,WWC1,CECR2,DDR2,PSD3,MFSD2A,HMGB1,IFFO1,PRKACB,KIAA0513,CADM2,OCIAD1,KCND3,RABGAP1L,SH3GLB1,ABI2,BSCL2,TMEM100" MicroRNA hsa-miR-1265:PITA hsa-miR-1265:PITA_TOP PITA 5.60E-08 3.03E-04 1.24E-07 1.13E-06 14 170 "ABAT,ASIC1,ITSN1,NLGN1,SOX5,CLASP2,WSCD1,TPM3,TENM4,RIMS4,BRINP3,KCNMA1,ATN1,GOPC" MicroRNA hsa-miR-299-5p:PITA hsa-miR-299-5p:PITA_TOP PITA 5.60E-08 3.03E-04 1.24E-07 1.13E-06 14 170 "CSMD3,WAC,FOXG1,ARHGAP5,CCDC88A,PHYHIPL,CAB39,CAMSAP2,BTRC,PCDH8,NLGN3,SULT4A1,USP54,RFX5" MicroRNA hsa-miR-136:PITA hsa-miR-136:PITA_TOP PITA 5.63E-08 3.05E-04 1.24E-07 1.14E-06 17 257 "EYA1,LRRTM4,ITSN1,CACHD1,RCOR3,NCAM1,GNG3,BTRC,ADGRL3,CAMK2G,PSD3,GRID1,HPCA,POU3F2,SYNC,ITGAV,RET" MicroRNA hsa-miR-625-5p:Functional MTI Functional MTI miRTarbase 5.74E-08 3.11E-04 1.27E-07 1.16E-06 16 227 "MDM4,ADAR,ANK1,SESN3,PKNOX2,WDTC1,RAP1GAP2,CAMK2A,BEST3,DLGAP3,UBTF,SPATA6,PTPA,BDNF-AS,EFNA3,GPR61" MicroRNA "GTGCAAT,MIR-25:MSigDB" "GTGCAAT,MIR-25:MSigDB" MSigDB 5.77E-08 3.12E-04 1.27E-07 1.16E-06 18 289 "SYNDIG1,CSMD3,DSCAML1,SCN3A,FOXG1,USP28,SESN3,TACC2,NFIA,PCDH11X,KCNK10,CDH10,NOMO2,FMN2,ITGAV,PTPRO,SLC17A6,BSDC1" MicroRNA "GTGCAAT,MIR-367:MSigDB" "GTGCAAT,MIR-367:MSigDB" MSigDB 5.77E-08 3.12E-04 1.27E-07 1.16E-06 18 289 "SYNDIG1,CSMD3,DSCAML1,SCN3A,FOXG1,USP28,SESN3,TACC2,NFIA,PCDH11X,KCNK10,CDH10,NOMO2,FMN2,ITGAV,PTPRO,SLC17A6,BSDC1" MicroRNA "GTGCAAT,MIR-32:MSigDB" "GTGCAAT,MIR-32:MSigDB" MSigDB 5.77E-08 3.12E-04 1.27E-07 1.16E-06 18 289 "SYNDIG1,CSMD3,DSCAML1,SCN3A,FOXG1,USP28,SESN3,TACC2,NFIA,PCDH11X,KCNK10,CDH10,NOMO2,FMN2,ITGAV,PTPRO,SLC17A6,BSDC1" MicroRNA "GTGCAAT,MIR-363:MSigDB" "GTGCAAT,MIR-363:MSigDB" MSigDB 5.77E-08 3.12E-04 1.27E-07 1.16E-06 18 289 "SYNDIG1,CSMD3,DSCAML1,SCN3A,FOXG1,USP28,SESN3,TACC2,NFIA,PCDH11X,KCNK10,CDH10,NOMO2,FMN2,ITGAV,PTPRO,SLC17A6,BSDC1" MicroRNA "GTGCAAT,MIR-92:MSigDB" "GTGCAAT,MIR-92:MSigDB" MSigDB 5.77E-08 3.12E-04 1.27E-07 1.16E-06 18 289 "SYNDIG1,CSMD3,DSCAML1,SCN3A,FOXG1,USP28,SESN3,TACC2,NFIA,PCDH11X,KCNK10,CDH10,NOMO2,FMN2,ITGAV,PTPRO,SLC17A6,BSDC1" MicroRNA "ACAGGGT,MIR-10A:MSigDB" "ACAGGGT,MIR-10A:MSigDB" MSigDB 5.85E-08 3.17E-04 1.29E-07 1.18E-06 12 120 "ITSN1,SON,NFASC,BTRC,CAMK2G,GRM3,HNRNPK,IGSF1,KCNA6,RPRD1A,ARHGAP12,ELAVL3" MicroRNA "ACAGGGT,MIR-10B:MSigDB" "ACAGGGT,MIR-10B:MSigDB" MSigDB 5.85E-08 3.17E-04 1.29E-07 1.18E-06 12 120 "ITSN1,SON,NFASC,BTRC,CAMK2G,GRM3,HNRNPK,IGSF1,KCNA6,RPRD1A,ARHGAP12,ELAVL3" MicroRNA hsa-miR-490-5p:PITA hsa-miR-490-5p:PITA_TOP PITA 6.11E-08 3.31E-04 1.34E-07 1.23E-06 13 145 "CCDC88A,GRIA2,TMEM257,CCSER2,ATRNL1,KIAA1755,TOX,WBP1L,KCNA1,PTPRD,SRGAP3,SNX27,DPP6" MicroRNA hsa-miR-223-3p:Functional MTI Functional MTI miRTarbase 6.28E-08 3.40E-04 1.38E-07 1.27E-06 11 98 "F3,FABP7,SESN3,ZNF365,ATM,NMNAT2,NFIA,ZEB1,PTBP2,PAX6,TOX" MicroRNA hsa-miR-517c:mirSVR_highEffct hsa-miR-517c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.30E-08 3.41E-04 1.38E-07 1.27E-06 17 259 "SYNDIG1,SLITRK1,SNX32,ERICH3,MIER1,SLCO1A2,SMARCE1,NFIA,WWC1,GRIA2,GRIA4,TJP1,TNS1,LRRTM3,OLFM3,SMG7,CBLN2" MicroRNA hsa-miR-27a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.53E-08 3.54E-04 1.43E-07 1.31E-06 22 429 "SLC25A25,ADAR,TOMM40L,SEMA6A,APC,GPAM,WDTC1,CAB39,ZNF638,NUDT21,OLR1,TGFBR3,ZNF384,PNKD,RGS6,CTNND1,BDNF-AS,ELMO1,CAB39L,ATN1,PHC2,EN2" MicroRNA hsa-miR-2114*:mirSVR_highEffct hsa-miR-2114*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.53E-08 3.54E-04 1.43E-07 1.31E-06 22 429 "ATAT1,SORCS1,FCGR1A,MOBP,BCAS1,SLC1A7,NRG3,MEGF11,GFAP,VAMP1,MAEL,PCSK2,HMGB1,CELF5,NCAN,ECE2,MASP1,GON4L,COPS7A,KCNK2,KCNMA1,ATG16L1" MicroRNA hsa-miR-1973:mirSVR_lowEffct hsa-miR-1973:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.66E-08 3.60E-04 1.46E-07 1.34E-06 17 260 "ZFYVE27,IL17D,KLHL32,FOXM1,ITSN1,ZNF365,MSR1,RCOR3,CADM3,LMO3,CRB1,FLRT1,FGFR1OP2,PLPPR1,PRTFDC1,OLFM3,KIF2A" MicroRNA hsa-miR-6890-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.85E-08 3.71E-04 1.50E-07 1.38E-06 23 467 "SRARP,DRAXIN,TESK2,MOG,KIAA1614,INKA2,WWC1,ACSL6,DIRAS1,CAMK2G,RFFL,ZNF384,FNDC5,HMGB1,SCRG1,A2ML1,RNF14,OSBPL3,FGFR1OP2,OCIAD1,ARHGAP12,PLEKHO1,UEVLD" MicroRNA hsa-miR-1224-5p:PITA hsa-miR-1224-5p:PITA_TOP PITA 7.04E-08 3.81E-04 1.54E-07 1.41E-06 12 122 "ITSN1,CPLX2,NFASC,ATF7,ZFP91,DCLK1,FNDC5,USP54,MAPK10,KCNA1,SV2A,RBM12" MicroRNA "ATGTTTC,MIR-494:MSigDB" "ATGTTTC,MIR-494:MSigDB" MSigDB 7.19E-08 3.89E-04 1.57E-07 1.44E-06 13 147 "DSCAML1,TACC2,API5,SHTN1,ARHGAP5,NSG2,SMARCE1,SON,NEUROD1,GRIK2,POU3F2,TMEM255A,LMO1" MicroRNA hsa-miR-516a-5p:mirSVR_lowEffct hsa-miR-516a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.20E-08 3.90E-04 1.58E-07 1.45E-06 24 506 "ASIC1,CSMD2,PAAF1,SLC14A1,NRG3,JPH4,NPAS3,GLS,PTBP2,CAMK2G,CRB1,LEFTY2,ANO5,ASIC3,DUSP26,CELF5,OSBPL3,PRKAB2,SPIRE1,CNIH3,SRGAP3,RAB5B,INSYN2,ZNF248" MicroRNA hsa-miR-105*:mirSVR_lowEffct hsa-miR-105*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.20E-08 3.90E-04 1.58E-07 1.45E-06 24 506 "ACER3,SRARP,WAC,FCGR1B,ERICH3,NLGN1,ASPH,WDTC1,NPAS3,ARHGEF7,ADGRL3,TBX15,BRSK2,OMG,CDC42,PDE1A,PIRT,PLXNB3,PTPRE,NTM,KCNK1,DPP6,NUP214,ELAVL3" MicroRNA hsa-miR-766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.31E-08 3.96E-04 1.60E-07 1.47E-06 16 231 "MAG,EMID1,DGKD,FAM168A,ASTN2,BTRC,CECR2,NEGR1,BTF3L4,PACSIN1,NAV2,WIPF2,RAB5B,PHC2,CACNG7,EN2" MicroRNA hsa-miR-1911:mirSVR_highEffct hsa-miR-1911:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.46E-08 4.04E-04 1.63E-07 1.50E-06 18 294 "RABEPK,CSMD3,GALNT13,UNC79,SLC30A10,ZNF365,DACH2,ASPH,SON,ENKUR,TCF12,GRIA4,GRIK4,MAEL,FNDC5,PLPPR4,ABCC9,RPRD1A" MicroRNA hsa-miR-1289:mirSVR_highEffct hsa-miR-1289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.68E-08 4.16E-04 1.68E-07 1.54E-06 23 470 "DUSP27,PKP4,ST3GAL3,ZNF365,MADD,SNAP25,SON,ILDR2,NMNAT2,FXYD6,NCAM1,LGI1,PDYN,SPATA6,MFSD4A,ATRNL1,VCAN,DNAH9,PLEKHB2,SLC25A41,SLC25A18,SUSD4,PHC2" MicroRNA hsa-miR-526a:PITA hsa-miR-526a:PITA_TOP PITA 7.71E-08 4.17E-04 1.68E-07 1.54E-06 12 123 "SORCS1,SCN3A,NMNAT2,JPH4,BCL2L2,CAMSAP2,BTRC,TPM3,NRXN2,BRINP3,DPP6,PAK5" MicroRNA hsa-miR-519b-5p:PITA hsa-miR-519b-5p:PITA_TOP PITA 7.71E-08 4.17E-04 1.68E-07 1.54E-06 12 123 "SORCS1,SCN3A,NMNAT2,JPH4,BCL2L2,CAMSAP2,BTRC,TPM3,NRXN2,BRINP3,DPP6,PAK5" MicroRNA hsa-miR-520c-5p:PITA hsa-miR-520c-5p:PITA_TOP PITA 7.71E-08 4.17E-04 1.68E-07 1.54E-06 12 123 "SORCS1,SCN3A,NMNAT2,JPH4,BCL2L2,CAMSAP2,BTRC,TPM3,NRXN2,BRINP3,DPP6,PAK5" MicroRNA hsa-miR-519c-5p:PITA hsa-miR-519c-5p:PITA_TOP PITA 7.71E-08 4.17E-04 1.68E-07 1.54E-06 12 123 "SORCS1,SCN3A,NMNAT2,JPH4,BCL2L2,CAMSAP2,BTRC,TPM3,NRXN2,BRINP3,DPP6,PAK5" MicroRNA hsa-miR-518d-5p:PITA hsa-miR-518d-5p:PITA_TOP PITA 7.71E-08 4.17E-04 1.68E-07 1.54E-06 12 123 "SORCS1,SCN3A,NMNAT2,JPH4,BCL2L2,CAMSAP2,BTRC,TPM3,NRXN2,BRINP3,DPP6,PAK5" MicroRNA "CTAGGAA,MIR-384:MSigDB" "CTAGGAA,MIR-384:MSigDB" MSigDB 7.82E-08 4.24E-04 1.71E-07 1.56E-06 9 60 "AQP4,NCAM1,ERBIN,GPM6B,RIMS4,PRKACB,SYTL2,SRGAP3,NAV2" MicroRNA hsa-miR-138:PITA hsa-miR-138:PITA_TOP PITA 7.85E-08 4.25E-04 1.71E-07 1.57E-06 17 263 "SEMA6A,ANK1,SH3GL2,YPEL4,RCOR3,SNCB,UNC5D,ADGRL3,TPM4,MEAF6,SNCAIP,RIMS3,SMG7,KCNMA1,CALN1,JMJD1C,RCAN2" MicroRNA hsa-miR-424-5p:Functional MTI Functional MTI miRTarbase 7.98E-08 4.32E-04 1.74E-07 1.60E-06 23 471 "ADORA3,CCDC80,NFIA,TGFBR3,TPM3,DLGAP3,NEGR1,ANLN,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,PTCH1,PTPRD,PLEKHB2,RTN4,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-216b-5p:TargetScan hsa-miR-216b-5p TargetScan 8.29E-08 4.49E-04 1.81E-07 1.66E-06 17 264 "MDM4,CSMD3,PKP4,NTNG1,KIF1B,NFIA,PAX6,DCLK1,HMGB1,NEGR1,PRKAB2,DZIP3,FAM131B,LRP8,RFX4,ABI2,ELAVL3" MicroRNA hsa-miR-147a:Functional MTI Functional MTI miRTarbase 8.43E-08 4.57E-04 1.84E-07 1.68E-06 13 149 "FGF14,SEMA6A,GFRA1,NCDN,CACNA1A,ZEB1,SLC22A6,NCAN,DPYSL5,JAKMIP2,BLOC1S6,TTLL7,EN2" MicroRNA hsa-miR-519e:PITA hsa-miR-519e:PITA_TOP PITA 8.64E-08 4.68E-04 1.88E-07 1.72E-06 14 176 "WAC,ANK3,YPEL4,CAB39,RBFOX2,CADM1,DPYSL5,KCNA1,KCNJ11,KCNK2,DLG2,RTN4,SLC6A15,EPB41" MicroRNA hsa-miR-1296:mirSVR_highEffct hsa-miR-1296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.73E-08 4.73E-04 1.90E-07 1.74E-06 16 234 "CNTNAP3,TOMM40L,TESK2,SFPQ,NTNG1,ASPH,RCOR3,BCL2L2,DDHD2,PIRT,CADM1,CAMKV,CTNND1,CSDE1,DBX2,SLC6A15" MicroRNA hsa-miR-513c:PITA hsa-miR-513c:PITA_TOP PITA 8.73E-08 4.73E-04 1.90E-07 1.74E-06 16 234 "SNX30,HPCAL4,FOXG1,SLITRK3,MEGF11,SOX1,CAB39,CPLX2,VAMP1,PPP2R5C,DOCK7,HP1BP3,PTPRD,ZYG11B,RBM12,ELAVL3" MicroRNA hsa-miR-517c:PITA hsa-miR-517c:PITA_TOP PITA 8.76E-08 4.74E-04 1.90E-07 1.75E-06 8 44 "SLITRK1,EIF4G3,CACNA1A,LRRTM3,OLFM3,SMG7,ZYG11B,CBLN2" MicroRNA hsa-miR-517a:PITA hsa-miR-517a:PITA_TOP PITA 8.76E-08 4.74E-04 1.90E-07 1.75E-06 8 44 "SLITRK1,EIF4G3,CACNA1A,LRRTM3,OLFM3,SMG7,ZYG11B,CBLN2" MicroRNA "TCTATGA,MIR-376A:MSigDB" "TCTATGA,MIR-376A:MSigDB" MSigDB 8.88E-08 4.81E-04 1.93E-07 1.77E-06 10 80 "KCNIP2,DSCAML1,ANK2,DCAF5,GRIK2,HES5,FAM131B,COPS7A,SIDT2,SLC4A10" MicroRNA "TCTATGA,MIR-376B:MSigDB" "TCTATGA,MIR-376B:MSigDB" MSigDB 8.88E-08 4.81E-04 1.93E-07 1.77E-06 10 80 "KCNIP2,DSCAML1,ANK2,DCAF5,GRIK2,HES5,FAM131B,COPS7A,SIDT2,SLC4A10" MicroRNA hsa-miR-202-5p:TargetScan hsa-miR-202-5p TargetScan 9.09E-08 4.92E-04 1.97E-07 1.81E-06 15 205 "LDLRAD3,PKP4,AHCYL1,MYRF,DDR2,PSD3,RBFOX2,PRMT8,MED1,CTNND2,HES5,KIAA0408,JAKMIP2,JMJD1C,EPB41" MicroRNA "TAATAAT,MIR-126:MSigDB" "TAATAAT,MIR-126:MSigDB" MSigDB 9.09E-08 4.92E-04 1.97E-07 1.81E-06 15 205 "EYA1,ARID1A,BCL2L2,ERBIN,DCLK2,DDR1,TCF12,GRIA2,PCSK2,HMGB1,CHD1L,PLEKHB2,ATN1,RFX4,SLC4A10" MicroRNA hsa-miR-492:mirSVR_highEffct hsa-miR-492:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.14E-08 4.95E-04 1.98E-07 1.82E-06 18 298 "NTNG1,ZCCHC17,ST3GAL3,ZNF365,SMARCE1,NDUFA5,PCDH11X,DCLK2,MFSD2A,TNS1,CTNND2,TOX,MAGI2,ZC3H11A,NTM,SLC25A48,ZYG11B,YY1AP1" MicroRNA hsa-miR-421:Functional MTI Functional MTI miRTarbase 9.25E-08 5.01E-04 2.01E-07 1.84E-06 16 235 "SLIT1,ATM,MYBPC1,NCDN,SYT4,BTRC,TCF7L2,FBXL16,ZMYND8,ARHGAP22,NEGR1,RIMS4,MAPK8,KCNN3,PARP11,RGR" MicroRNA hsa-miR-515-3p:PITA hsa-miR-515-3p:PITA_TOP PITA 9.27E-08 5.02E-04 2.01E-07 1.84E-06 14 177 "WAC,ANK3,YPEL4,CAB39,RBFOX2,CADM1,DPYSL5,KCNA1,KCNJ11,KCNK2,DLG2,RTN4,SLC6A15,EPB41" MicroRNA hsa-miR-10a*:mirSVR_highEffct hsa-miR-10a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.43E-08 5.11E-04 2.04E-07 1.87E-06 19 332 "EYA1,CLIP1,SLITRK1,LRRC7,PPFIA1,DOCK10,API5,SLC14A1,PHYHIPL,KIF1B,CAMK2G,GRIA2,LGI1,TMEFF2,SPATA6,OSBPL3,PAK5,ABCC9,EPB41L2" MicroRNA hsa-miR-4668-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.49E-08 5.14E-04 2.05E-07 1.88E-06 21 402 "ATAT1,MDM4,SOX6,SALL3,SPART,DCLK2,GNG3,USP2,ZFP91,GPR37L1,HMGB1,NEGR1,PRDM2,NAV2,WIPF2,DPP6,ABCC9,ZYG11B,VANGL2,GPR61,BSCL2" MicroRNA hsa-miR-375:Functional MTI Functional MTI miRTarbase 1.00E-07 5.42E-04 2.16E-07 1.99E-06 23 477 "F3,DGKD,CCDC88A,EIF4G3,SON,CAB39,AHCYL1,NCAM1,WWC1,TCF12,NUDT21,TMEM25,ZFP91,CDC42,TNS1,RBPJ,KIAA0513,RIMS3,KCNQ2,SYT15,ABI2,ELAVL4,YY1AP1" MicroRNA hsa-miR-4253:mirSVR_highEffct hsa-miR-4253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-07 5.62E-04 2.25E-07 2.06E-06 23 478 "MDM4,ADARB2,KLHL32,ERMN,TOMM40L,PKP4,ZNF365,CADPS,ATP1A2,GAD2,ZSWIM8,FXYD6,SLCO1C1,ANO4,TIE1,PDYN,CASC2,PPP3CB,RGS6,COPS7A,KCNA6,KCNC1,PEX5" MicroRNA hsa-miR-34c-3p:PITA hsa-miR-34c-3p:PITA_TOP PITA 1.04E-07 5.63E-04 2.25E-07 2.06E-06 16 237 "FHL1,SOX6,NTNG1,MAGI3,SLITRK3,CCDC88A,MYT1L,GLS,PCDH11X,GPM6A,GRM3,PTPRD,PTPRE,KIF2A,ABI1,RCAN2" MicroRNA hsa-miR-1248:PITA hsa-miR-1248:PITA_TOP PITA 1.04E-07 5.63E-04 2.25E-07 2.06E-06 16 237 "EYA1,AHCYL1,BCL2L2,CAMK2G,CD81,CADM1,NXPH1,MED1,CTNND1,PROX1,FGFR1OP2,DLG2,BSDC1,ZYG11B,FAM135B,EPB41L1" MicroRNA hsa-miR-4722-5p:Functional MTI Functional MTI miRTarbase 1.04E-07 5.66E-04 2.26E-07 2.07E-06 26 595 "SDE2,APC2,ADAR,KIAA1109,SFMBT2,SLC2A5,ASPH,KBTBD12,ATM,GJB1,FAM168A,ZNF638,BTRC,DDR1,PTBP2,NUCB1,TPM3,GPR37L1,LRTM2,MFSD4A,KIAA0513,BLOC1S6,KCNJ11,SNX27,GNE,SYT15" MicroRNA "GACAGGG,MIR-339:MSigDB" "GACAGGG,MIR-339:MSigDB" MSigDB 1.05E-07 5.68E-04 2.27E-07 2.08E-06 9 62 "FHL1,NFASC,HAP1,GRM3,HNRNPK,NRXN1,NXPH1,KCNMA1,SLC4A10" MicroRNA hsa-miR-197:PITA hsa-miR-197:PITA_TOP PITA 1.07E-07 5.77E-04 2.30E-07 2.11E-06 13 152 "RBM10,EYA1,SEMA6A,PPM1E,NLGN1,CCDC88A,NKX2-2,CECR2,GRIA2,MEAF6,CTNND1,KCNA1,PIANP" MicroRNA hsa-miR-23b*:mirSVR_highEffct hsa-miR-23b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-07 5.82E-04 2.32E-07 2.13E-06 21 405 "ACLY,CHST15,RUFY2,CGREF1,RCOR3,ATP1A2,NDUFA5,GNAS,CDC42,PADI2,PDYN,PLXNB3,CNTN1,MICAL2,NRSN1,ECE2,SIRPA,KCNJ9,PCDH15,PYGM,PLEKHB2" MicroRNA hsa-miR-920:mirSVR_highEffct hsa-miR-920:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-07 5.99E-04 2.39E-07 2.19E-06 25 557 "SLC44A5,GPR158,ANK3,CGREF1,SPHKAP,NMNAT2,GART,SPART,BCL2L2,ADHFE1,VAMP1,POPDC3,PRLHR,NUMA1,GPR88,ZNF384,PDE4B,COL9A2,MICAL2,USP54,CNIH3,C1orf109,CAMK1G,RFX4,RGR" MicroRNA hsa-let-7b-5p:Functional MTI Functional MTI miRTarbase 1.12E-07 6.05E-04 2.41E-07 2.21E-06 40 1215 "ASIC1,LGR4,WLS,MDM4,TUBB4A,FOXRED2,DRAXIN,TOMM40L,AMPH,PAAF1,SON,AHCYL1,SALL3,GNAS,GPM6B,NRDC,PSD3,RFFL,TGFBR3,TJP1,CD81,RBFOX2,TPM4,ADGRG1,HMGB1,FADS2,FTO,RBPJ,USP54,PUM1,DPYSL5,ZC3H11A,SMG7,KIF2A,DNAH9,C12orf4,NUP214,RBM12,SH3GLB1,PLEKHO1" MicroRNA hsa-miR-328-3p:TargetScan hsa-miR-328-3p TargetScan 1.15E-07 6.24E-04 2.48E-07 2.28E-06 13 153 "ASIC1,LGR4,GRAMD1B,HPCAL4,KIAA1614,CCDC88A,RAP1GAP2,HAP1,MFSD2A,PADI2,KIF2A,EN2,EPB41L1" MicroRNA hsa-miR-6768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.31E-04 2.51E-07 2.30E-06 11 104 "ADARB2,WAC,GOLGA7B,JAKMIP3,CAMSAP2,TCF7L2,RBFOX2,CADM1,ZFYVE9,CEP170,KCNN3" MicroRNA "GCACCTT,MIR-18B:MSigDB" "GCACCTT,MIR-18B:MSigDB" MSigDB 1.17E-07 6.31E-04 2.51E-07 2.30E-06 11 104 "ADD3,CCDC88A,SON,C11orf87,CLASP2,CAMSAP2,PSD3,CDC42,PACSIN1,PRKACB,EPB41L1" MicroRNA "GCACCTT,MIR-18A:MSigDB" "GCACCTT,MIR-18A:MSigDB" MSigDB 1.17E-07 6.31E-04 2.51E-07 2.30E-06 11 104 "ADD3,CCDC88A,SON,C11orf87,CLASP2,CAMSAP2,PSD3,CDC42,PACSIN1,PRKACB,EPB41L1" MicroRNA hsa-miR-518f:mirSVR_highEffct hsa-miR-518f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-07 6.32E-04 2.51E-07 2.30E-06 16 239 "TTYH1,FHL1,ANK1,PPFIA1,TACC2,NSG2,NDUFA5,TGFBR3,LGI1,CHGA,ACBD5,PPP3CB,PRDM2,PRTFDC1,PARP11,DTNA" MicroRNA "GACTGTT,MIR-212:MSigDB" "GACTGTT,MIR-212:MSigDB" MSigDB 1.24E-07 6.73E-04 2.67E-07 2.45E-06 13 154 "SCN3A,SEMA6A,SOX6,BCAN,LRRC55,SOX5,NMNAT2,PTBP2,PPP2R5C,CSDE1,KCNA6,SRGAP3,KCNK2" MicroRNA "GACTGTT,MIR-132:MSigDB" "GACTGTT,MIR-132:MSigDB" MSigDB 1.24E-07 6.73E-04 2.67E-07 2.45E-06 13 154 "SCN3A,SEMA6A,SOX6,BCAN,LRRC55,SOX5,NMNAT2,PTBP2,PPP2R5C,CSDE1,KCNA6,SRGAP3,KCNK2" MicroRNA hsa-miR-484:PITA hsa-miR-484:PITA_TOP PITA 1.24E-07 6.73E-04 2.67E-07 2.45E-06 13 154 "RTN3,FGF1,FHL1,ANK1,SOX5,NFIA,PTPRE,DLG2,DPP6,BSDC1,RET,PHC2,RASGRP2" MicroRNA hsa-miR-122:PITA hsa-miR-122:PITA_TOP PITA 1.29E-07 6.97E-04 2.76E-07 2.54E-06 11 105 "SORCS1,ERICH3,PPM1E,ADGRB2,NCAM1,GPM6B,NLGN3,NEGR1,CTNND2,PMEPA1,DLG2" MicroRNA "TGCAAAC,MIR-452:MSigDB" "TGCAAAC,MIR-452:MSigDB" MSigDB 1.29E-07 6.97E-04 2.76E-07 2.54E-06 11 105 "SORCS1,SGIP1,ANK1,ANK3,ATP2B2,KIF1B,NKX2-2,CACNB2,PCDH8,PCDH9,ATL1" MicroRNA "AGGGCAG,MIR-18A:MSigDB" "AGGGCAG,MIR-18A:MSigDB" MSigDB 1.31E-07 7.07E-04 2.80E-07 2.57E-06 12 129 "ZFYVE27,MAPT,ARID1A,URGCP,SLC8A2,JPH4,CPLX2,ATF7,CAMKV,PSD,SNX27,PHC2" MicroRNA hsa-miR-623:PITA hsa-miR-623:PITA_TOP PITA 1.31E-07 7.07E-04 2.80E-07 2.57E-06 12 129 "GPR158,NLGN1,RND1,SEPT3,CACNA1A,GPR19,TCF12,DCLK1,RBFOX2,ZNF384,RIMS4,PTPRD" MicroRNA hsa-miR-205-5p:Functional MTI Functional MTI miRTarbase 1.31E-07 7.09E-04 2.81E-07 2.58E-06 14 182 "RTN3,SLC25A25,CLIP1,LRRTM4,VAMP1,GNAS,ZEB1,NUDT21,HMGB1,MED1,RGS6,KCNJ10,JMJD1C,PHC2" MicroRNA hsa-miR-518d-3p:mirSVR_highEffct hsa-miR-518d-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.31E-07 7.09E-04 2.81E-07 2.58E-06 14 182 "TTYH1,FHL1,TACC2,NSG2,NDUFA5,ARHGEF7,TGFBR3,LGI1,PRMT8,CHGA,PPP3CB,PRDM2,PARP11,DTNA" MicroRNA hsa-miR-4731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-07 7.09E-04 2.81E-07 2.58E-06 20 374 "PNMA8B,TUBB4A,FOXRED2,DRAXIN,EMC1,RAP1GAP2,BCL2L2,WWC1,GRIK3,MFSD2A,NEURL1,HMGB1,BTF3L4,SPATA6,RGS6,OCIAD1,KCND3,RABGAP1L,RAB5B,ABI2" MicroRNA hsa-miR-486-5p:mirSVR_highEffct hsa-miR-486-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.33E-07 7.19E-04 2.84E-07 2.61E-06 22 447 "KLHL32,NLGN1,ARHGAP5,GPR153,CSPG5,RCOR3,IDI2-AS1,SMOC1,NEUROD1,PSRC1,WSCD1,RFFL,TMEM25,CADM1,PLXNB3,CRLS1,PPP3CB,KCNK2,RFX4,RBM12,SLC4A10,BAALC" MicroRNA hsa-miR-758:PITA hsa-miR-758:PITA_TOP PITA 1.34E-07 7.26E-04 2.87E-07 2.63E-06 13 155 "ABAT,CDC42BPA,ATP2B2,NEUROD1,UNC5D,MAGI1,CADM1,POU3F2,SYTL2,CSDE1,DLG2,SLC6A15,SLC4A10" MicroRNA "GTCTTCC,MIR-7:MSigDB" "GTCTTCC,MIR-7:MSigDB" MSigDB 1.34E-07 7.26E-04 2.87E-07 2.63E-06 13 155 "CSMD3,HPCAL4,SLC6A9,SLC8A3,SHANK2,ATP2B2,GABBR1,CLASP2,TCF12,DIRAS1,PAX6,PIK3CD,CCSER2" MicroRNA hsa-miR-99a:mirSVR_lowEffct hsa-miR-99a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-07 7.63E-04 3.01E-07 2.76E-06 15 212 "MOG,DOCK10,SLC8A2,SLC14A1,MYT1L,ALDH1L1,BEST3,BEST1,DOCK7,PRKCZ,EDRF1,PLPPR4,NTM,TTLL7,EPB41L1" MicroRNA hsa-miR-3175:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-07 7.65E-04 3.02E-07 2.77E-06 17 274 "CLIP1,PDZD4,CLSTN1,ASPH,LHFPL4,ADGRB2,NDUFA5,FAM168A,DIRAS1,TMPRSS5,UBTF,CCSER2,PTPA,RGS6,PHYHIP,PTPRE,ELAVL3" MicroRNA hsa-miR-151-5p:mirSVR_highEffct hsa-miR-151-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-07 7.70E-04 3.04E-07 2.79E-06 12 130 "CDC7,SLC44A5,CACHD1,SNAP25,ZNF638,PTBP2,SEZ6L,LGI1,KCNJ10,KCNK1,RNF220,ELAVL3" MicroRNA hsa-miR-133a-3p:Functional MTI Functional MTI miRTarbase 1.42E-07 7.70E-04 3.04E-07 2.79E-06 12 130 "EMID1,MEG3,SNX30,SESN3,BCAN,NCDN,ZEB1,RFFL,CDC42,TPM3,PDE1A,RBPJ" MicroRNA hsa-miR-504:mirSVR_highEffct hsa-miR-504:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.43E-07 7.73E-04 3.05E-07 2.80E-06 20 376 "TMEM74,KLHL32,DKK3,MYT1L,GART,ZNF638,ASTN2,GRM3,ZDHHC22,ANLN,FTO,FEZ1,RAB39A,PKN2,GON4L,CEP170,NTM,KCNK2,INSYN2,FGFBP3" MicroRNA hsa-miR-340-5p:Functional MTI Functional MTI miRTarbase 1.43E-07 7.73E-04 3.05E-07 2.80E-06 19 341 "ACER3,CLIP1,KIAA1109,USP28,CAPRIN2,SON,CAB39,TNS1,TLX1,RIMS4,PUM1,CSDE1,PTPRD,NTM,KCNK1,RAB5B,ARHGAP12,ELAVL4,RCAN2" MicroRNA hsa-miR-1286:mirSVR_highEffct hsa-miR-1286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-07 7.93E-04 3.13E-07 2.87E-06 24 526 "GPR158,FGF14,CNIH2,NTNG1,BCAS1,ASPH,SON,NAP1L2,VAMP1,SYT4,GNAS,CNTN2,CACNA1A,PTPN5,MFSD2A,CDH10,HNRNPK,ST8SIA5,HP1BP3,KCNJ11,KCNK1,RAD52,RBM12,ABI2" MicroRNA hsa-miR-210:PITA hsa-miR-210:PITA_TOP PITA 1.48E-07 8.01E-04 3.15E-07 2.89E-06 7 32 "SEMA6A,SLC8A3,NCAM1,CAMTA1,SEMA5B,EFNA3,RCAN2" MicroRNA hsa-miR-518c:mirSVR_highEffct hsa-miR-518c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-07 8.06E-04 3.17E-07 2.91E-06 17 275 "TTYH1,FHL1,ANK1,PPFIA1,TACC2,NSG2,NDUFA5,TGFBR3,LGI1,CHGA,ACBD5,PPP3CB,PRDM2,PRTFDC1,TMEM255A,PARP11,DTNA" MicroRNA hsa-miR-3163:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-07 8.09E-04 3.18E-07 2.92E-06 19 342 "SDE2,ACER3,MRVI1,CLIP1,USP28,SON,MYBPC1,AJAP1,RBFOX2,TPM3,ST8SIA5,MEAF6,BTF3L4,OSBPL3,ATRNL1,MAPK8,PTPRD,WIPF2,ELAVL4" MicroRNA hsa-miR-519e:mirSVR_highEffct hsa-miR-519e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-07 8.09E-04 3.18E-07 2.92E-06 27 647 "KLHL32,WAC,HPCAL4,ANK3,PPFIA1,NTNG1,ASPH,ATP1A2,KIF1B,NCAM1,RND1,GLS,CAMTA1,TCF12,NUMA1,GRIA4,IGSF21,CHGA,JAM2,P2RY12,BDNF-AS,BLOC1S6,DLG2,ABI1,SLC6A15,EPB41,EPB41L2" MicroRNA hsa-miR-627-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-07 8.09E-04 3.18E-07 2.92E-06 18 308 "ADCYAP1R1,GPAM,ASCL1,IGSF9B,NEUROD1,NUDT21,SYT6,P2RX7,TNS1,VCAN,CADM2,BLOC1S6,NAV2,FAM13C,PAK5,JMJD1C,TMEM100,UEVLD" MicroRNA hsa-miR-1238:mirSVR_highEffct hsa-miR-1238:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-07 8.11E-04 3.19E-07 2.93E-06 15 213 "SLITRK1,SEMA6C,API5,URGCP,SORCS3,ATM,C11orf87,GNAS,CELF3,MAGI1,PRMT8,JAM2,RGS6,JAKMIP2,ELAVL4" MicroRNA hsa-miR-877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-07 8.31E-04 3.27E-07 3.00E-06 26 607 "ACLY,ARID1A,SLC25A25,GRAMD1B,TMEM156,ANK1,ANK2,URGCP,DKK3,ERBIN,VAMP1,ZNF638,NODAL,EML4,TMEM151B,NUCB1,AIFM1,HMGB1,HNRNPK,SLC22A6,CADM1,VAV2,RGS6,RAB5B,PLEKHB2,EPB41" MicroRNA hsa-miR-190:PITA hsa-miR-190:PITA_TOP PITA 1.56E-07 8.43E-04 3.31E-07 3.04E-06 13 157 "SLITRK1,NLGN1,PHYHIPL,NEUROD1,ANO4,PCDH9,CADM1,NEGR1,POU3F2,CA10,CEP170,MAGI2,KCNA4" MicroRNA hsa-miR-6826-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-07 8.43E-04 3.31E-07 3.04E-06 13 157 "ACTN2,WAC,ATP1A2,DCAF5,GPR26,TMEM151B,DDR2,GRID1,PADI2,PNKD,TENM4,KCNJ10,ABI2" MicroRNA hsa-miR-532-3p:PITA hsa-miR-532-3p:PITA_TOP PITA 1.56E-07 8.43E-04 3.31E-07 3.04E-06 13 157 "WAC,EIF4G3,NMNAT2,CAMK2G,ZNF384,NRXN2,CAMKV,PSD,STMN4,BSDC1,PHC2,GPR61,ELAVL3" MicroRNA hsa-miR-190b:PITA hsa-miR-190b:PITA_TOP PITA 1.56E-07 8.43E-04 3.31E-07 3.04E-06 13 157 "SLITRK1,NLGN1,PHYHIPL,NEUROD1,ANO4,PCDH9,CADM1,NEGR1,POU3F2,CA10,CEP170,MAGI2,KCNA4" MicroRNA hsa-miR-4267:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-07 8.43E-04 3.31E-07 3.04E-06 13 157 "ZFYVE27,SLC25A25,INKA2,CYB561A3,LEFTY2,TMPRSS5,ARHGAP22,CCSER2,ELMO1,SNX27,WIPF2,ABI2,EPB41" MicroRNA hsa-miR-3184-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-07 8.68E-04 3.40E-07 3.12E-06 14 185 "MDM4,PNMA8B,SLC2A5,ASPH,NKX6-2,NFASC,GJB1,AJAP1,B4GALNT4,GRID1,OLR1,PFKFB3,NOS1AP,WIPF2" MicroRNA hsa-miR-4459:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-07 8.71E-04 3.41E-07 3.13E-06 28 691 "MDM4,SLC30A10,MAGI3,SLC2A5,ASPH,KBTBD12,ATM,KIF21B,ACSBG1,LUZP2,GNAS,GNG4,BTRC,DDR1,NUCB1,PSD3,TPM3,JAM2,PIK3CD,CCSER2,PACSIN1,FAT3,ACBD5,KIAA0513,HP1BP3,DNAH9,RAB5B,DNM2" MicroRNA hsa-miR-30a-5p:Functional MTI Functional MTI miRTarbase 1.64E-07 8.90E-04 3.49E-07 3.20E-06 29 734 "CDC7,CHST15,SEMA6A,FOXG1,USP16,MTR,ATM,SON,NCAM1,NEUROD1,ZNF638,EML4,NUCB1,RBFOX2,ZMYND8,SERPINE2,CAMKV,PIK3CD,PTPA,PPP2R5C,PPP3CB,DOCK7,CTNND1,MAPK8,SEC61A2,RNF220,RPRD1A,SLC4A10,EPB41" MicroRNA hsa-miR-181a*:mirSVR_lowEffct hsa-miR-181a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-07 8.91E-04 3.49E-07 3.20E-06 18 310 "ZFYVE27,SRARP,GALNT13,ST3GAL3,SLC1A7,GABBR1,GNAS,AZIN2,VSTM2A,MS4A7,COL9A2,MED1,KCNA1,SRGAP3,KCNN3,OLIG1,ABCC9,ABI2" MicroRNA hsa-miR-519e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-07 9.28E-04 3.63E-07 3.33E-06 14 186 "GPR158,SNAP25,DKK3,CAB39,GANAB,CACNA1A,PTGDR2,PDE1A,CELF5,BTF3L4,PRKAB2,FAM131B,FGFR1OP2,ZNF248" MicroRNA hsa-miR-769-3p:mirSVR_highEffct hsa-miR-769-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-07 9.37E-04 3.67E-07 3.36E-06 23 492 "FABP7,SMARCE1,RCOR3,AHCYL1,B4GALNT1,RAP1GAP2,SPART,INKA2,GLS,GRIA1,GRIA4,RFFL,TNFRSF1B,LGI1,SNCAIP,CA10,JAKMIP2,ELMO1,HP1BP3,PTPRE,KCNMA1,SEC61A2,RCAN2" MicroRNA hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA_TOP PITA 1.83E-07 9.89E-04 3.87E-07 3.55E-06 17 279 "KCNIP2,ANK3,PPM1E,RUFY2,CLASP2,NFIA,CAMTA1,CAMSAP2,UNC5D,OPCML,ZFP91,FNDC5,RIMS4,PRKAB2,CSDE1,SRGAP3,SH3GLB1" MicroRNA hsa-miR-134:PITA hsa-miR-134:PITA_TOP PITA 1.83E-07 9.90E-04 3.87E-07 3.55E-06 12 133 "ASIC1,AMPH,MAGI3,MYT1L,KIF1B,ADGRL3,EML4,PSD3,ARHGEF4,CEP170,DLG2,DSCAM" MicroRNA hsa-miR-425*:mirSVR_highEffct hsa-miR-425*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.95E-07 1.06E-03 4.14E-07 3.80E-06 14 188 "DRAXIN,ZNF365,SOX5,ZCCHC24,TTLL9,NPAS3,NCAM1,BRSK2,TMEFF2,GDAP1L1,NRXN2,C11orf49,MED1,DTNA" MicroRNA "AACATTC,MIR-409-3P:MSigDB" "AACATTC,MIR-409-3P:MSigDB" MSigDB 1.98E-07 1.07E-03 4.20E-07 3.85E-06 12 134 "SOX6,USP33,GPR88,TGFBR3,PCDH9,TPM3,PDE4B,HNRNPK,GDAP1L1,CTNND1,TOX,KCNMA1" MicroRNA hsa-miR-596:mirSVR_highEffct hsa-miR-596:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-07 1.08E-03 4.21E-07 3.86E-06 18 314 "ATAT1,PPFIA1,APBA2,NTNG1,MAGI3,JAKMIP3,SHTN1,MT3,FAM168A,CACNB2,GRIA2,ADAMTS8,ACBD5,CNRIP1,PPP3CB,RAB3IL1,DNM2,ATL1" MicroRNA "TCTGATA,MIR-361:MSigDB" "TCTGATA,MIR-361:MSigDB" MSigDB 1.99E-07 1.08E-03 4.21E-07 3.86E-06 10 87 "LGR4,ADCY2,ADD3,SON,PCDH9,MAGI1,PDE4B,CTNND2,NTM,PEX5" MicroRNA "GGCAGCT,MIR-22:MSigDB" "GGCAGCT,MIR-22:MSigDB" MSigDB 2.02E-07 1.10E-03 4.27E-07 3.92E-06 15 218 "MBP,LDLRAD3,RYR1,PDZD4,WDTC1,MIR4697HG,BRSK2,ZFP91,KCNK10,ZFYVE9,PIK3CD,RIMS4,SV2A,RAB5B,DSCAM" MicroRNA hsa-miR-6745:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-07 1.13E-03 4.40E-07 4.04E-06 14 189 "ECSIT,PNMA8B,PDZD4,MAGI3,GNG4,CECR2,NUCB1,TPM3,UBTF,PACSIN1,SIRPA,RAB5B,GNE,ABI2" MicroRNA hsa-miR-515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-07 1.13E-03 4.40E-07 4.04E-06 14 189 "GPR158,SNAP25,DKK3,CAB39,GANAB,CACNA1A,PTGDR2,PDE1A,CELF5,BTF3L4,PRKAB2,FAM131B,FGFR1OP2,ZNF248" MicroRNA hsa-miR-208b:mirSVR_highEffct hsa-miR-208b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.09E-07 1.13E-03 4.40E-07 4.04E-06 14 189 "FOXG1,RCOR3,TMEM108,SALL3,GNAS,ZEB1,GRIA2,GRIA4,GPR88,CADM1,CELF5,PPP2R5C,PCDH15,RGS7" MicroRNA hsa-miR-3919:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.09E-07 1.13E-03 4.40E-07 4.04E-06 13 161 "SYT9,TUBB4A,SGIP1,BCAS1,SON,ARHGEF7,GPM6B,TCF7L2,MEAF6,SF1,KIAA1755,KIAA0513,WIPF2" MicroRNA hsa-miR-378a-3p:TargetScan hsa-miR-378a-3p TargetScan 2.09E-07 1.13E-03 4.40E-07 4.04E-06 13 161 "FOXG1,CDC42BPA,EIF4G3,BCL2L2,NEUROD1,PSD3,GRIK3,RIMS4,KIF2A,CALN1,DSCAM,RASGRF1,ABI2" MicroRNA hsa-miR-497-5p:Functional MTI Functional MTI miRTarbase 2.17E-07 1.17E-03 4.56E-07 4.19E-06 22 460 "ADORA3,CCDC80,BTRC,TGFBR3,TPM3,DLGAP3,NEGR1,ANLN,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,PTPRD,PLEKHB2,RTN4,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-1273e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-07 1.17E-03 4.56E-07 4.19E-06 22 460 "ANK1,CCDC80,ASTN1,ATM,SCN3B,ACSBG1,GNG4,PTBP2,NUDT21,NUCB1,CADM1,IFFO1,FAT3,ACBD5,PRKACB,CTNND1,KIAA0513,CADM2,HP1BP3,DNAH9,PARP11,SEC61A2" MicroRNA hsa-miR-7-5p:Functional MTI Functional MTI miRTarbase 2.21E-07 1.20E-03 4.66E-07 4.27E-06 25 578 "SDE2,EMID1,ACTN2,FGF1,ZNF365,SLC6A9,C10orf105,GFRA1,GLS,GPR19,HAP1,RFFL,CYB561A3,PAX6,PLEKHB1,PIK3CD,PMP2,CRLS1,RBPJ,PMEPA1,KCNJ10,PARP11,PHC2,SSPN,CACNG7" MicroRNA hsa-miR-18b:PITA hsa-miR-18b:PITA_TOP PITA 2.23E-07 1.21E-03 4.68E-07 4.30E-06 14 190 "ADD3,GPR158,CCDC88A,IGSF9B,CLASP2,PSD3,DAAM2,CDC42,TPM3,KIAA0513,CADM2,KCNA1,INSYN2,EPB41L1" MicroRNA hsa-miR-6780a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-07 1.21E-03 4.68E-07 4.30E-06 14 190 "SLC25A25,ASIC4,SLC7A14,ACSBG1,ZNF638,GRIK3,TGFBR3,REPS2,PTGDR2,RBFOX2,SLC22A6,GDAP1L1,TMCC2,BSDC1" MicroRNA hsa-miR-18a:PITA hsa-miR-18a:PITA_TOP PITA 2.23E-07 1.21E-03 4.68E-07 4.30E-06 14 190 "ADD3,GPR158,CCDC88A,IGSF9B,CLASP2,PSD3,DAAM2,CDC42,TPM3,KIAA0513,CADM2,KCNA1,INSYN2,EPB41L1" MicroRNA hsa-miR-3190-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.47E-07 1.34E-03 5.19E-07 4.76E-06 17 285 "MAG,RTKN,FOXRED2,HOGA1,MAGI3,GPAM,SLC1A2,URGCP,LUZP2,TCF7L2,TPM3,ZNF384,PTPA,MAPK8,KIAA0513,RGMA,ABI2" MicroRNA "AGGTGCA,MIR-500:MSigDB" "AGGTGCA,MIR-500:MSigDB" MSigDB 2.47E-07 1.34E-03 5.19E-07 4.76E-06 10 89 "SORCS1,FOXG1,GPM6A,KCNK10,LRRTM3,CA10,PLPPR4,DLG3,ATL1,EPB41L1" MicroRNA "AGCTCCT,MIR-28:MSigDB" "AGCTCCT,MIR-28:MSigDB" MSigDB 2.47E-07 1.34E-03 5.19E-07 4.76E-06 10 89 "DPF1,ACHE,ARID1A,NDRG2,PDZD4,AMPH,GPM6A,HNRNPK,NTM,EN2" MicroRNA hsa-miR-4300:mirSVR_highEffct hsa-miR-4300:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-07 1.34E-03 5.20E-07 4.77E-06 21 426 "SLC44A5,SPHKAP,SORCS3,NMNAT2,SPART,ADHFE1,VAMP1,POPDC3,PRLHR,NUMA1,GPR88,ZNF384,A2ML1,COL9A2,USP54,CNIH3,SLC6A15,CAMK1G,RFX4,RGR,GPR61" MicroRNA hsa-miR-6856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.37E-03 5.31E-07 4.87E-06 16 253 "MAG,CDC42BPA,SFMBT2,PALLD,WDTC1,B4GALNT4,GRID1,PFKFB3,ZFYVE9,MICAL2,NAV2,NKAIN1,RAB5B,PIANP,ABI2,EPB41L1" MicroRNA hsa-miR-637:PITA hsa-miR-637:PITA_TOP PITA 2.53E-07 1.37E-03 5.31E-07 4.87E-06 12 137 "MAPT,CNIH2,CPLX2,NCDN,CACNA1A,GRIN1,FBXL16,RBFOX2,NRXN2,RAB5B,PHC2,RNF220" MicroRNA hsa-miR-363-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.37E-03 5.31E-07 4.87E-06 14 192 "ECSIT,PNMA8B,PDZD4,MAGI3,GNG4,CECR2,NUCB1,TPM3,UBTF,PACSIN1,SIRPA,RAB5B,GNE,ABI2" MicroRNA hsa-miR-486-3p:PITA hsa-miR-486-3p:PITA_TOP PITA 2.59E-07 1.40E-03 5.43E-07 4.98E-06 13 164 "MAPT,TESK2,CNIH2,YPEL4,SOX10,ATF7,TCF12,GRIN1,FNDC5,NRXN2,RIMS4,SRGAP3,RNF220" MicroRNA hsa-miR-1225-3p:mirSVR_highEffct hsa-miR-1225-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-07 1.40E-03 5.44E-07 4.99E-06 17 286 "ZFYVE27,SYT9,MEG3,ECSIT,FHL1,ITSN1,CCDC80,ST3GAL3,SLIT1,GABBR1,GPR162,C1orf94,PCDH9,ECE2,SLC6A15,ARHGEF10L,RNF220" MicroRNA hsa-miR-188-5p:PITA hsa-miR-188-5p:PITA_TOP PITA 2.70E-07 1.46E-03 5.65E-07 5.18E-06 14 193 "ASIC1,GPR158,MYT1L,LMO3,ERBIN,PCDH11X,CAMTA1,CACNA1A,ZFP91,PCDH9,RBFOX2,PDE3B,NSD2,ACBD5" MicroRNA hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 2.81E-07 1.52E-03 5.89E-07 5.40E-06 16 255 "LGR4,FABP7,SOX6,DOCK10,B3GAT1,SOX5,CAMSAP2,EML4,CCSER2,FAT3,KCNJ9,RAB5B,CALN1,PARP11,RTN4,YY1AP1" MicroRNA hsa-miR-642a-5p:Functional MTI Functional MTI miRTarbase 2.87E-07 1.55E-03 6.01E-07 5.51E-06 15 224 "ASIC4,DKK3,ZNF638,NODAL,TMEM151B,GRID1,OLR1,ZDHHC22,CDH8,GPR37L1,SLC22A6,TENM4,RGS6,ST8SIA3,VANGL2" MicroRNA hsa-miR-620:PITA hsa-miR-620:PITA_TOP PITA 2.97E-07 1.61E-03 6.23E-07 5.71E-06 13 166 "SEMA6A,LMO3,RGL1,UNC5D,WWC1,TBX15,TJP1,LGI1,NXPH1,RIMS4,KIAA1755,HS3ST4,PHC2" MicroRNA hsa-miR-1270:PITA hsa-miR-1270:PITA_TOP PITA 2.97E-07 1.61E-03 6.23E-07 5.71E-06 13 166 "SEMA6A,LMO3,RGL1,UNC5D,WWC1,TBX15,TJP1,LGI1,NXPH1,RIMS4,KIAA1755,HS3ST4,PHC2" MicroRNA hsa-miR-346:PITA hsa-miR-346:PITA_TOP PITA 3.07E-07 1.66E-03 6.42E-07 5.89E-06 9 70 "SORCS3,CADM3,NCDN,AJAP1,PTPN5,CCDC136,NXPH1,SF1,DLG2" MicroRNA hsa-miR-6760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-07 1.84E-03 7.11E-07 6.53E-06 15 227 "DPF1,RTKN,CCDC88A,WDTC1,NDUFA5,GFRA1,ASTN2,HAP1,TMPRSS5,PTPA,RGS6,MICAL2,KIAA0513,NKAIN1,RAB5B" MicroRNA hsa-miR-136*:mirSVR_highEffct hsa-miR-136*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.42E-07 1.85E-03 7.14E-07 6.55E-06 13 168 "KLHL32,UNC79,NTNG1,SLC14A1,ADHFE1,GNAS,B4GALNT4,INA,ZBTB16,DLG2,DBX2,NUP214,TMEM100" MicroRNA hsa-miR-365:PITA hsa-miR-365:PITA_TOP PITA 3.42E-07 1.85E-03 7.14E-07 6.55E-06 13 168 "ANK3,CACHD1,API5,SORCS3,UNC5D,TLL2,PDYN,NMT2,FMN2,PLEKHB2,EFNA3,RBM12,ARHGAP12" MicroRNA hsa-miR-6758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-07 1.88E-03 7.23E-07 6.64E-06 16 259 "MAG,CDC42BPA,SFMBT2,PALLD,WDTC1,B4GALNT4,GRID1,PFKFB3,ZFYVE9,MICAL2,NAV2,NKAIN1,RAB5B,PIANP,ABI2,EPB41L1" MicroRNA hsa-miR-554:PITA hsa-miR-554:PITA_TOP PITA 3.47E-07 1.88E-03 7.25E-07 6.65E-06 9 71 "PALLD,BTRC,CACNB2,BTF3L4,MAGI2,SMG7,SV2A,ABI1,EFNA3" MicroRNA hsa-miR-1269:PITA hsa-miR-1269:PITA_TOP PITA 3.57E-07 1.94E-03 7.46E-07 6.84E-06 11 116 "SLITRK1,SNAP25,CAB39,AHCYL1,NEUROD1,ANO4,TCF12,GRIK2,LGI1,C11orf49,SLC4A10" MicroRNA hsa-miR-1298:mirSVR_highEffct hsa-miR-1298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.60E-07 1.95E-03 7.51E-07 6.89E-06 15 228 "LRRC7,BCAR3,ITSN1,ZNF365,YPEL4,SNAP25,NMNAT2,DNER,NCAM1,KAZN,GRIA2,MFSD2A,PCDH9,LRRTM3,COPS7A" MicroRNA "CCAGGGG,MIR-331:MSigDB" "CCAGGGG,MIR-331:MSigDB" MSigDB 3.75E-07 2.03E-03 7.81E-07 7.17E-06 10 93 "SEMA6A,YPEL4,GABBR1,CPLX2,USP2,NSD2,RIMS4,C1orf109,RAB5B,PHC2" MicroRNA hsa-miR-6830-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-07 2.03E-03 7.81E-07 7.17E-06 10 93 "TTYH1,NAXD,SMOC1,TNR,NEGR1,KIAA1755,PMEPA1,KCNN3,DPP6,ELAVL3" MicroRNA hsa-miR-193b-3p:Functional MTI Functional MTI miRTarbase 3.80E-07 2.06E-03 7.92E-07 7.26E-06 31 853 "ZFYVE27,ARID1A,RTKN,SFPQ,CLSTN1,ZNF365,MTR,EMC1,KIF1B,INKA2,NFIA,BTRC,PSRC1,TCF7L2,NUCB1,ATP13A2,TGFBR3,TNFRSF1B,ARHGAP19,ZNF384,HMGB1,TJP2,VAV2,NSD2,PPP2R5C,TENM4,MAPK8,HP1BP3,RGMA,NUP214,ABI2" MicroRNA hsa-miR-142-3p:PITA hsa-miR-142-3p:PITA_TOP PITA 3.91E-07 2.12E-03 8.15E-07 7.48E-06 14 199 "ANK3,APC,SOX5,RAP1GAP2,EML4,INA,PDE4B,ZMYND8,HMGB1,FAT3,CTNND1,PUM1,ITGAV,ATG16L1" MicroRNA hsa-miR-342-3p:TargetScan hsa-miR-342-3p TargetScan 4.02E-07 2.18E-03 8.38E-07 7.68E-06 15 230 "MDM4,COLGALT2,GFRA1,MLC1,NKX2-2,GRIN1,PDE3B,CAMKV,NOMO2,DNAJC6,LRP8,KCNA4,DSCAM,RPRD1A,ABI2" MicroRNA hsa-miR-154-5p:TargetScan hsa-miR-154-5p TargetScan 4.25E-07 2.30E-03 8.85E-07 8.11E-06 11 118 "RIMKLA,PKNOX2,LUZP2,CAMK2G,FBXL16,GUCY1A2,DCLK1,CADM2,KCNA2,CDH20,RAB5B" MicroRNA hsa-miR-4691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-07 2.30E-03 8.85E-07 8.12E-06 15 231 "GRAMD1B,SLIT1,SMARCE1,NODAL,TMEM151B,DDR2,GRID1,GRIK3,TNS1,CDH8,HMGB1,SLC22A6,TENM4,KCNJ4,FAM13C" MicroRNA hsa-miR-875-5p:TargetScan hsa-miR-875-5p TargetScan 4.42E-07 2.40E-03 9.20E-07 8.44E-06 9 73 "EYA1,PPM1E,NFIA,CECR2,GRID1,NEGR1,FTO,PACSIN1,ELAVL4" MicroRNA hsa-miR-518e:mirSVR_highEffct hsa-miR-518e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.47E-07 2.42E-03 9.30E-07 8.53E-06 13 172 "TTYH1,FHL1,TACC2,NSG2,MEGF11,SON,MLC1,WSCD1,PCDHGA3,PC,BEST3,ARHGAP22,PPP3CB" MicroRNA hsa-miR-6792-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.49E-07 2.43E-03 9.33E-07 8.56E-06 15 232 "GRAMD1B,SLIT1,SMARCE1,NODAL,TMEM151B,DDR2,GRID1,GRIK3,TNS1,CDH8,HMGB1,SLC22A6,TENM4,KCNJ4,FAM13C" MicroRNA hsa-miR-425-5p:TargetScan hsa-miR-425-5p TargetScan 4.69E-07 2.54E-03 9.74E-07 8.94E-06 14 202 "AMPH,ANK3,KIF21B,CAB39,NCAM1,AIFM1,PDE3B,RNF14,CTNND1,NOS1AP,PTCH1,CAB39L,FAM135B,ELAVL4" MicroRNA hsa-miR-548as-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.78E-07 2.59E-03 9.93E-07 9.11E-06 13 173 "MDM4,BCAN,SLC1A2,SON,NPAS3,NDUFA5,AJAP1,NUDT21,NRXN1,NEGR1,SF1,ATRNL1,CADM2" MicroRNA hsa-miR-331-3p:Functional MTI Functional MTI miRTarbase 4.80E-07 2.60E-03 9.97E-07 9.15E-06 20 406 "ARID1A,WAC,SFPQ,APBB1,DGKZ,NCDN,FAM168A,GNAS,GPR26,CAMK2G,TMEM151B,NEURL1,VAV2,PLCH2,CTNND1,TOMM20,NUP214,ABI2,EN2,EPB41L2" MicroRNA hsa-miR-1273:mirSVR_lowEffct hsa-miR-1273:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.92E-07 2.67E-03 1.02E-06 9.37E-06 22 483 "LINC00461,SLC30A10,ALDH4A1,TTLL9,GANAB,NFIA,HAP1,AZIN2,OPCML,PAX6,SEZ6L,ASIC3,UBTF,PNKD,PRKCG,KIAA0408,ANKS1B,LRRTM3,CEP170,ST8SIA3,INSYN2,ELAVL4" MicroRNA hsa-miR-1182:PITA hsa-miR-1182:PITA_TOP PITA 5.04E-07 2.73E-03 1.05E-06 9.58E-06 11 120 "ASIC1,ARID1A,API5,PCDH11X,ANO4,CAMK2G,CELF3,DCLK1,PPP3CB,MAPK10,SRGAP3" MicroRNA hsa-miR-1304-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.18E-07 2.80E-03 1.07E-06 9.85E-06 23 524 "SRARP,DRAXIN,TESK2,MOG,KIAA1614,INKA2,WWC1,CNDP1,ACSL6,DIRAS1,RFFL,FBXL16,ZDHHC22,CDH8,ZNF384,FNDC5,HMGB1,SCRG1,A2ML1,RNF14,FGFR1OP2,PLEKHO1,UEVLD" MicroRNA hsa-miR-548aw:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.20E-07 2.81E-03 1.08E-06 9.88E-06 16 267 "ADARB2,FOXRED2,GAS7,CCDC80,SPART,UNC5D,FAM69C,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-216a-5p:TargetScan hsa-miR-216a-5p TargetScan 5.20E-07 2.81E-03 1.08E-06 9.88E-06 16 267 "ARID1A,CSMD3,GOLGA7B,NTNG1,NLGN1,LRRC4C,KIF21B,GFRA1,RFFL,HMGB1,CADM1,CADM2,LRP8,MAGI2,DTNA,OLIG2" MicroRNA "GGCACAT,MIR-455:MSigDB" "GGCACAT,MIR-455:MSigDB" MSigDB 5.31E-07 2.87E-03 1.10E-06 1.01E-05 8 55 "ADD3,SOX6,SPHKAP,DCAF5,TJP1,RIMS4,HES5,RFX4" MicroRNA hsa-miR-1256:PITA hsa-miR-1256:PITA_TOP PITA 5.42E-07 2.93E-03 1.12E-06 1.03E-05 12 147 "EYA1,LRRC7,CAPRIN2,SMARCE1,CAB39,RFFL,PCDH9,TUB,CTNND2,SRGAP3,TMEM255A,RGS7" MicroRNA hsa-miR-220b:PITA hsa-miR-220b:PITA_TOP PITA 5.42E-07 2.93E-03 1.12E-06 1.03E-05 12 147 "RBM10,PPM1E,ERBIN,RND1,NKX2-2,CAMK2G,CECR2,DCLK1,PDE4B,CTNND1,KCNA1,C1orf109" MicroRNA hsa-miR-2681-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.42E-07 2.93E-03 1.12E-06 1.03E-05 12 147 "ACER3,ARID1A,ADARB2,NPAS3,NEUROD1,NUDT21,RBPJ,PROX1,KCNN3,JMJD1C,ABI2,ELAVL3" MicroRNA hsa-miR-154-3p:TargetScan hsa-miR-154-3p TargetScan 5.47E-07 2.96E-03 1.13E-06 1.04E-05 11 121 "ASIC1,CSMD3,APC,JAKMIP3,GPM6A,GPR26,REPS2,ANKS1B,MAGI2,RNF220,RPRD1A" MicroRNA hsa-miR-487a-3p:TargetScan hsa-miR-487a-3p TargetScan 5.47E-07 2.96E-03 1.13E-06 1.04E-05 11 121 "ASIC1,CSMD3,APC,JAKMIP3,GPM6A,GPR26,REPS2,ANKS1B,MAGI2,RNF220,RPRD1A" MicroRNA hsa-miR-3177-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.59E-07 3.03E-03 1.16E-06 1.06E-05 9 75 "ARID1A,SLITRK3,TACC2,RPH3A,GRIK3,HMGB1,TUB,DOCK7,ABI2" MicroRNA hsa-miR-4685-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.74E-07 3.11E-03 1.19E-06 1.09E-05 16 269 "SRARP,FAM43B,TACC2,TMEM151A,DKK3,GJB1,ZNF638,GRID1,RFFL,ZDHHC22,CDH8,TLX1,SLC22A6,ZBTB16,SMG7,RAB5B" MicroRNA hsa-miR-618:PITA hsa-miR-618:PITA_TOP PITA 5.74E-07 3.11E-03 1.19E-06 1.09E-05 16 269 "NLGN4X,SOX6,CDC42BPA,PHYHIPL,DNER,PCDH11X,GPM6A,OPCML,TJP1,TPD52,MAGI1,NEGR1,BTF3L4,PACSIN1,MED1,PMEPA1" MicroRNA hsa-miR-122-5p:Functional MTI Functional MTI miRTarbase 5.76E-07 3.12E-03 1.19E-06 1.09E-05 25 609 "TMEM74,MDM4,ADCY2,SCN4B,ANK2,USP28,ANXA7,SLITRK3,ATP1A2,NMNAT2,NASP,NCAM1,BCL2L2,NCDN,NODAL,WWC1,TMEM136,CNDP1,VWC2,OLR1,NLGN3,UBTF,MEAF6,PARP11,ZYG11B" MicroRNA "CAGCACT,MIR-512-3P:MSigDB" "CAGCACT,MIR-512-3P:MSigDB" MSigDB 5.83E-07 3.16E-03 1.20E-06 1.10E-05 12 148 "ACER3,SYNDIG1,NTNG1,ATP2B2,MYT1L,CAMTA1,PTBP2,CCKBR,ZFP91,SEMA5B,PRRX1,STMN4" MicroRNA hsa-miR-433-3p:TargetScan hsa-miR-433-3p TargetScan 5.89E-07 3.19E-03 1.21E-06 1.11E-05 15 237 "CLIP1,MIER1,ILDR2,ALDH1L1,AIFM1,ANO5,NEGR1,NMT2,MED1,MAPK8,HP1BP3,ABCC9,RBM12,RPRD1A,GPR61" MicroRNA hsa-miR-1298-5p:TargetScan hsa-miR-1298-5p TargetScan 5.95E-07 3.22E-03 1.23E-06 1.13E-05 11 122 "APC,ATP2B2,NCAM1,KAZN,BTRC,B4GALNT4,KIAA1549L,BTF3L4,FAM131B,LRRTM3,ABI2" MicroRNA hsa-miR-329:mirSVR_highEffct hsa-miR-329:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.00E-07 3.25E-03 1.24E-06 1.14E-05 27 695 "TOMM40L,LRRTM4,BCAS1,PAAF1,MIER1,CAPRIN2,ASPH,NRG3,EIF4G3,DKK3,NDUFA5,DCAF5,SYT4,DCLK2,BTRC,ZEB1,PTBP2,CRMP1,RNF14,PRKACB,EDRF1,GON4L,KCNC1,GNE,ARHGEF10L,SYT15,CBLN2" MicroRNA hsa-miR-1295:mirSVR_lowEffct hsa-miR-1295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.03E-07 3.26E-03 1.24E-06 1.14E-05 16 270 "FCGR1B,TOMM40L,TESK2,ASIC4,NTNG1,BCAN,ZSWIM8,KAZN,GNAS,MS4A7,FTO,FAT3,PLPP4,MASP1,DLG2,ARHGAP12" MicroRNA hsa-miR-4287:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.03E-07 3.26E-03 1.24E-06 1.14E-05 16 270 "SRARP,FAM43B,TACC2,TMEM151A,DKK3,GJB1,ZNF638,GRID1,RFFL,ZDHHC22,CDH8,TLX1,SLC22A6,ZBTB16,SMG7,RAB5B" MicroRNA hsa-miR-181b-5p:Functional MTI Functional MTI miRTarbase 6.06E-07 3.28E-03 1.25E-06 1.14E-05 19 375 "EPS8,MEG3,SLC25A25,CAPRIN2,BRINP2,ATM,RAP1GAP2,GANAB,NFIA,NRDC,GRIA2,HMGB1,NMT2,NSD2,PNKD,OSBPL3,SPIRE1,RPRD1A,EN2" MicroRNA "ATAACCT,MIR-154:MSigDB" "ATAACCT,MIR-154:MSigDB" MSigDB 6.12E-07 3.32E-03 1.26E-06 1.16E-05 8 56 "WAC,PPM1E,PKNOX2,TCF12,CAMK2G,FBXL16,FGFR1OP2,RAB5B" MicroRNA hsa-miR-660-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-07 3.41E-03 1.30E-06 1.19E-05 19 376 "CHST15,MOG,JAKMIP3,SLIT1,GJB1,CNDP1,GPR26,GRID1,LEFTY2,HMGB1,SCRG1,TLX1,SLC22A6,DPYSL5,PTAFR,RABGAP1L,KCNJ11,FAM13C,VWA5A" MicroRNA hsa-miR-3926:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.36E-07 3.44E-03 1.31E-06 1.20E-05 17 305 "MAG,MAPT,RTKN,FOXRED2,HOGA1,GOLGA7B,MAGI3,GPAM,URGCP,SOX5,LUZP2,ADAMTS8,TPM3,MAPK8,RGMA,CEP170,SIDT2" MicroRNA hsa-miR-1286:PITA hsa-miR-1286:PITA_TOP PITA 6.46E-07 3.50E-03 1.33E-06 1.22E-05 11 123 "CSMD2,GAS7,NFASC,VAMP1,GNG3,CNTN2,GRIN1,HNRNPK,KCNMA1,DLG2,RBM12" MicroRNA "ATAGGAA,MIR-202:MSigDB" "ATAGGAA,MIR-202:MSigDB" MSigDB 6.74E-07 3.65E-03 1.39E-06 1.27E-05 10 99 "LDLRAD3,SORCS1,SFPQ,CCDC88A,ERBIN,TCF12,MED1,KIAA0408,RAD52,VANGL2" MicroRNA hsa-miR-340*:mirSVR_highEffct hsa-miR-340*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.82E-07 3.70E-03 1.40E-06 1.29E-05 19 378 "ACER3,MDM4,F3,PLEKHG5,ANK3,PPFIA1,CACHD1,PAAF1,CAPRIN2,ZSWIM8,PLXNB3,IFFO1,MFSD4A,CHD1L,MICAL2,PRKCG,RAD52,RFX4,SYT15" MicroRNA hsa-miR-483-3p.2:TargetScan hsa-miR-483-3p.2 TargetScan 7.00E-07 3.79E-03 1.44E-06 1.32E-05 11 124 "ACER3,MDM4,GABBR1,KIF21B,GANAB,PRUNE2,CAMK2G,AIFM1,ACBD5,MED1,RAB5B" MicroRNA hsa-miR-323-5p:PITA hsa-miR-323-5p:PITA_TOP PITA 7.02E-07 3.80E-03 1.44E-06 1.32E-05 9 77 "SOX6,DGKD,CLASP2,GANAB,SEMA4A,UNC5D,CDH8,PSD,GPR61" MicroRNA "ACATATC,MIR-190:MSigDB" "ACATATC,MIR-190:MSigDB" MSigDB 7.04E-07 3.81E-03 1.45E-06 1.33E-05 8 57 "SLITRK1,NLGN1,NFASC,NEUROD1,ANO4,PAX6,PCDH9,PTHLH" MicroRNA hsa-miR-208a:mirSVR_highEffct hsa-miR-208a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.05E-07 3.82E-03 1.45E-06 1.33E-05 13 179 "FOXG1,RCOR3,TMEM108,GNAS,ZEB1,GRIA2,GRIA4,GPR88,CADM1,CELF5,PPP2R5C,PLPPR4,RGS7" MicroRNA hsa-miR-4469:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.28E-07 3.94E-03 1.49E-06 1.37E-05 17 308 "SRARP,ASIC4,TACC2,SHANK2,GJB1,ACSBG1,ZNF638,NODAL,TMEM151B,GRID1,OLR1,ZDHHC22,CDH8,ZBTB16,SMG7,TMCC2,ST8SIA3" MicroRNA hsa-miR-6867-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.48E-07 4.05E-03 1.53E-06 1.41E-05 14 210 "SRARP,TACC2,ZCCHC24,GJB1,ACSBG1,ZNF638,ACSL6,GRID1,RFFL,ZDHHC22,PADI2,CDH8,SMG7,EPB41L1" MicroRNA hsa-miR-1296:PITA hsa-miR-1296:PITA_TOP PITA 7.49E-07 4.05E-03 1.53E-06 1.41E-05 7 40 "TESK2,SFPQ,CAMK2G,CADM1,CSDE1,TMEM255A,SLC6A15" MicroRNA hsa-miR-6499-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-07 4.06E-03 1.54E-06 1.41E-05 31 881 "PLEKHG5,ADCY2,SLC30A10,MAGI3,CCDC80,SFMBT2,KBTBD12,SCN3B,GNG4,WWC1,CNDP1,VWC2,PTBP2,TPM3,SCRG1,JAM2,CCSER2,MEAF6,FAT3,ACBD5,OSBPL3,DOCK7,KIAA0513,HP1BP3,WIPF2,DNAH9,PLEKHB2,ZYG11B,SYT15,ABI2,UEVLD" MicroRNA hsa-miR-331-3p:PITA hsa-miR-331-3p:PITA_TOP PITA 7.59E-07 4.11E-03 1.55E-06 1.43E-05 11 125 "DPF1,CSMD2,WLS,PKNOX2,YPEL4,ADGRL3,RIMS4,PTPRD,C1orf109,RAB5B,PHC2" MicroRNA "GTACTGT,MIR-101:MSigDB" "GTACTGT,MIR-101:MSigDB" MSigDB 7.66E-07 4.15E-03 1.57E-06 1.44E-05 15 242 "ASIC1,EYA1,ARID1A,UNC79,PPFIA1,ERBIN,NEUROD1,CAMTA1,CACNB2,PCDH8,MAGI1,NEGR1,ZNF385B,MAGI2,EPB41L1" MicroRNA hsa-miR-6793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.75E-07 4.20E-03 1.59E-06 1.46E-05 12 152 "RTN3,WLS,PLEKHG5,DKK3,RAP1GAP2,SMOC1,ZNF638,CACNA1A,KCNK10,ARHGAP19,FAM181B,ELMO1" MicroRNA hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA_TOP PITA 8.07E-07 4.37E-03 1.65E-06 1.51E-05 15 243 "ITSN1,PKP4,ATP1A2,NEUROD1,PTBP2,CAMK2G,PSD3,PCDH8,PDE1C,CELF5,BTF3L4,CSDE1,SMG7,EPB41L2,RCAN2" MicroRNA hsa-miR-629:PITA hsa-miR-629:PITA_TOP PITA 8.31E-07 4.50E-03 1.70E-06 1.56E-05 12 153 "ERMN,SNX30,SEMA6A,ARHGAP5,CADPS,SOX5,GAD2,NCAM1,BTRC,MED1,USP54,MAPK10" MicroRNA hsa-miR-6736-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.49E-07 4.60E-03 1.74E-06 1.59E-05 15 244 "PNMA8B,MOG,JAKMIP3,SLC1A7,LHFPL4,C11orf87,WWC1,RFFL,LEFTY2,SCRG1,TMPRSS5,A2ML1,TENM4,ELMO1,WIPF2" MicroRNA hsa-miR-1825:PITA hsa-miR-1825:PITA_TOP PITA 8.51E-07 4.61E-03 1.74E-06 1.60E-05 13 182 "HPCAL4,CNIH2,CACNB2,NUMA1,PDE1C,PDYN,UBTF,SF1,PKN2,STMN4,RTN4,PHC2,GPR61" MicroRNA hsa-miR-3181:mirSVR_lowEffct hsa-miR-3181:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.69E-07 4.71E-03 1.78E-06 1.63E-05 17 312 "CLSTN1,ASCL1,RCOR3,GLS,AKNA,FBXL16,TLL2,NLGN3,P2RY12,SF1,SNCAIP,NKAIN4,RABGAP1L,KCNK2,FAM66C,L1CAM,RASGRP2" MicroRNA "GCTCTTG,MIR-335:MSigDB" "GCTCTTG,MIR-335:MSigDB" MSigDB 8.76E-07 4.74E-03 1.79E-06 1.64E-05 9 79 "SORCS1,ZSWIM8,PSD3,PCDH9,NRXN1,VAV2,FAM131B,BSDC1,ARHGAP12" MicroRNA hsa-miR-345:PITA hsa-miR-345:PITA_TOP PITA 8.90E-07 4.82E-03 1.82E-06 1.67E-05 10 102 "EPS8,PPM1E,SORBS1,SYT4,CELF3,PDE4B,MED1,USP54,OLFM3,RBM12" MicroRNA hsa-let-7a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.90E-07 4.82E-03 1.82E-06 1.67E-05 10 102 "ARID1A,WAC,USP28,FYN,TMEM136,OLR1,HMGB1,CADM1,DOCK7,ABI2" MicroRNA hsa-miR-6809-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.90E-07 4.82E-03 1.82E-06 1.67E-05 10 102 "TACC2,HMGB1,UBTF,RBPJ,PUM1,PSD,DPYSL5,RAB5B,DNM2,PHC2" MicroRNA hsa-miR-361-5p:TargetScan hsa-miR-361-5p TargetScan 9.37E-07 5.07E-03 1.91E-06 1.75E-05 14 214 "MDM4,ADCY2,FOXM1,PKP4,AJAP1,NFIA,PRUNE2,BRSK2,PDE4B,KIAA1549L,CTNND1,PARP11,EPB41,RCAN2" MicroRNA hsa-miR-200c-3p:Functional MTI Functional MTI miRTarbase 9.37E-07 5.07E-03 1.91E-06 1.75E-05 14 214 "NLGN4X,SLC1A2,RCOR3,CAB39,NCAM1,ERBIN,CAMSAP2,TCF7L2,ZEB1,PSD3,PRKCZ,PTPRD,PTPRZ1,ABI2" MicroRNA hsa-miR-889:PITA hsa-miR-889:PITA_TOP PITA 9.73E-07 5.27E-03 1.98E-06 1.82E-05 16 280 "BCAR3,MAGI3,CCDC88A,SORCS3,GLS,CAMSAP2,TBX15,OLR1,REPS2,NEGR1,OSBPL3,ATRNL1,CTNND2,PTPRD,ABI1,ARHGAP12" MicroRNA hsa-miR-622:PITA hsa-miR-622:PITA_TOP PITA 9.90E-07 5.36E-03 2.02E-06 1.85E-05 15 247 "LGR4,EYA1,AMPH,API5,CCDC88A,ZSWIM8,CAMTA1,UNC5D,PTBP2,KCNK2,DLG2,TMEM255A,SUSD4,RGS7,RNF220" MicroRNA hsa-miR-335-5p:TargetScan hsa-miR-335-5p TargetScan 9.90E-07 5.36E-03 2.02E-06 1.85E-05 14 215 "HPCAL4,BCL2L2,FAM168A,PSD3,GUCY1A2,RBFOX2,GPR37L1,NRXN1,FAT3,OSBPL3,MAPK10,FAM131B,RBM12,PLEKHO1" MicroRNA hsa-miR-183-5p:Functional MTI Functional MTI miRTarbase 1.00E-06 5.42E-03 2.04E-06 1.87E-05 18 351 "MDM4,SLC25A25,API5,ARFGAP2,TMEM108,DKK3,ERBIN,BTRC,ZEB1,PFKFB3,MEAF6,PTPA,PSMD13,KIF2A,RAB5B,PLEKHB2,RALGDS,RTN4" MicroRNA hsa-miR-584:PITA hsa-miR-584:PITA_TOP PITA 1.02E-06 5.54E-03 2.08E-06 1.91E-05 13 185 "WAC,ANK3,AQP4,CADPS,PALLD,DNER,PRRX1,RGS6,PKN2,PUM1,DNAJC6,KIF2A,ZYG11B" MicroRNA hsa-miR-142-3p:Functional MTI Functional MTI miRTarbase 1.05E-06 5.66E-03 2.13E-06 1.95E-05 19 389 "PPFIA1,DOCK10,APC,NAP1L2,SYT4,GNAS,TMEM136,EML4,ZMYND8,HMGB1,NSD2,ACBD5,RAB39A,PUM1,ITGAV,KCND3,ATG16L1,ABCC9,ARHGAP12" MicroRNA hsa-miR-369-5p:mirSVR_lowEffct hsa-miR-369-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-06 5.67E-03 2.13E-06 1.95E-05 14 216 "ACER3,ATAT1,SCN4B,LINC00461,ANK3,SLC14A1,TBX15,SYT6,VSTM2A,FLRT1,PTPRE,JMJD1C,RGS7,ELAVL4" MicroRNA hsa-miR-15b-5p:Functional MTI Functional MTI miRTarbase 1.05E-06 5.71E-03 2.14E-06 1.97E-05 28 760 "WAC,ADORA3,CCDC80,GANAB,BTRC,CYB561A3,TGFBR3,TPD52,TPM3,HNRNPK,DLGAP3,NEGR1,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,CSDE1,PTPRD,PLEKHB2,RTN4,NUP214,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA "GGGCATT,MIR-365:MSigDB" "GGGCATT,MIR-365:MSigDB" MSigDB 1.07E-06 5.77E-03 2.16E-06 1.99E-05 10 104 "ADD3,API5,SLC8A2,USP33,TLL2,PAX6,FMN2,SRGAP3,RBM12,ARHGAP12" MicroRNA hsa-miR-15a-5p:Functional MTI Functional MTI miRTarbase 1.08E-06 5.87E-03 2.20E-06 2.02E-05 27 717 "ADORA3,CCDC80,SOX5,GANAB,BTRC,CYB561A3,TGFBR3,TPM3,DLGAP3,CADM1,NEGR1,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,CSDE1,PTPRD,PLEKHB2,RTN4,RET,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-323-5p:mirSVR_highEffct hsa-miR-323-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-06 5.88E-03 2.20E-06 2.02E-05 19 390 "ATAT1,CCDC80,DGKD,NLGN1,TTLL9,CLASP2,NELL1,RGL1,SEMA4A,GPM6B,CRB1,TNR,CDH8,WBP1L,KCNK2,PHC2,SSPN,PRRT4,SEZ6" MicroRNA hsa-miR-590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-06 5.88E-03 2.20E-06 2.02E-05 19 390 "RTN3,WAC,FOXG1,SESN3,APC,KIAA1614,DKK3,PCDH11X,ZEB1,PTBP2,NUCB1,GRIK4,OLR1,PAH,HNRNPK,MAPK8,JMJD1C,SSPN,EPB41L1" MicroRNA hsa-miR-6868-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-06 5.89E-03 2.21E-06 2.02E-05 13 186 "GALNT13,LRRTM4,ASIC4,CDC42BPA,SFMBT2,KLHL4,FAM69C,DDR1,NUDT21,TNS1,HMGB1,NEGR1,RIMS3" MicroRNA hsa-miR-23a-3p:Functional MTI Functional MTI miRTarbase 1.10E-06 5.93E-03 2.22E-06 2.04E-05 15 249 "ATAT1,ADD3,NLGN4X,FOXM1,NEK6,ERBIN,GLS,TPM3,CAMKV,CRLS1,CSDE1,BSDC1,SLC6A15,JMJD1C,EN2" MicroRNA hsa-miR-515-3p:mirSVR_highEffct hsa-miR-515-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-06 5.94E-03 2.22E-06 2.04E-05 26 674 "WAC,HPCAL4,ANK3,PPFIA1,NTNG1,SORBS1,ASPH,RCOR3,ATP1A2,NRG3,KIF1B,NCAM1,RND1,GLS,CAMTA1,TCF12,NUMA1,CHGA,JAM2,BDNF-AS,BLOC1S6,DLG2,ABI1,SLC6A15,EPB41,EPB41L2" MicroRNA hsa-miR-6734-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-06 6.08E-03 2.27E-06 2.08E-05 11 130 "PNMA8B,SLC2A5,ASPH,ASTN1,NDUFA5,SMOC1,AJAP1,OLR1,TPD52,NOS1AP,PTPRE" MicroRNA hsa-miR-603:Functional MTI Functional MTI miRTarbase 1.13E-06 6.14E-03 2.29E-06 2.10E-05 22 508 "ATAT1,CSMD2,ADCYAP1R1,CHST15,DRAXIN,MOBP,SGIP1,ANK3,WDTC1,AJAP1,ZDHHC22,KCNK10,UBTF,FAT3,SF1,CRLS1,RIMS3,LRP8,MED24,KCNA4,KCNK1,FGFBP3" MicroRNA hsa-miR-151-3p:PITA hsa-miR-151-3p:PITA_TOP PITA 1.17E-06 6.31E-03 2.36E-06 2.16E-05 10 105 "YPEL4,CLASP2,VAMP1,GRM3,RGS6,PKN2,BRINP3,SYNC,SRGAP3,WIPF2" MicroRNA hsa-miR-339-5p:PITA hsa-miR-339-5p:PITA_TOP PITA 1.20E-06 6.52E-03 2.44E-06 2.23E-05 9 82 "IGSF9B,HAP1,ZFP91,HNRNPK,NRXN1,NXPH1,MAGI2,INSYN2,SLC4A10" MicroRNA hsa-miR-181a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-06 6.52E-03 2.44E-06 2.23E-05 9 82 "ARID1A,PNMA8B,GRAMD1B,NSG2,ATP1A3,PPP3CB,NOS1AP,PSD,SEC61A2" MicroRNA hsa-miR-6838-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-06 6.55E-03 2.44E-06 2.24E-05 20 431 "ADORA3,CCDC80,TGFBR3,TPM3,DLGAP3,NEGR1,VAV2,PPP2R5C,OSBPL3,RBPJ,ZBTB16,RIMS3,PHYHIP,PTPRD,PLEKHB2,RTN4,SIDT2,ARHGAP12,EN2,TMEM100" MicroRNA hsa-miR-575:PITA hsa-miR-575:PITA_TOP PITA 1.23E-06 6.64E-03 2.48E-06 2.27E-05 13 188 "CSMD3,FGF1,ANK3,PTBP2,GRIA2,PDE1C,FNDC5,NEGR1,NXPH1,TOX,CADM2,KCNA1,PHC2" MicroRNA hsa-miR-125b:PITA hsa-miR-125b:PITA_TOP PITA 1.23E-06 6.66E-03 2.48E-06 2.28E-05 17 320 "DIRAS1,HRH3,CAMKV,SULT4A1,PPP2R5C,NCAN,FAM131B,PHYHIP,ZC3H11A,KCNA1,SNX27,WIPF2,GOPC,FAM135B,PHC2,VANGL2,SLC4A10" MicroRNA hsa-miR-125a-5p:PITA hsa-miR-125a-5p:PITA_TOP PITA 1.23E-06 6.66E-03 2.48E-06 2.28E-05 17 320 "DIRAS1,HRH3,CAMKV,SULT4A1,PPP2R5C,NCAN,FAM131B,PHYHIP,ZC3H11A,KCNA1,SNX27,WIPF2,GOPC,FAM135B,PHC2,VANGL2,SLC4A10" MicroRNA hsa-miR-375:TargetScan hsa-miR-375 TargetScan 1.23E-06 6.68E-03 2.49E-06 2.28E-05 14 219 "ASCL1,EIF4G3,NFIA,GRIK2,PAX6,CADM1,KIAA1549L,PACSIN1,RBPJ,DLG3,ABI2,ELAVL3,ELAVL4,EPB41L2" MicroRNA hsa-let-7g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-06 6.88E-03 2.56E-06 2.35E-05 10 106 "ARID1A,WAC,USP28,FYN,TMEM136,OLR1,HMGB1,CADM1,DOCK7,ABI2" MicroRNA hsa-miR-181a-5p:Functional MTI Functional MTI miRTarbase 1.29E-06 7.00E-03 2.61E-06 2.39E-05 23 553 "EPS8,MEG3,SLC25A25,KLRC4,USP28,MADD,CAPRIN2,ATM,SOX5,FXYD6,GANAB,TGFBR3,NMT2,NSD2,PNKD,OSBPL3,PUM1,PROX1,SPIRE1,C1orf109,PTPRZ1,ARHGAP12,EN2" MicroRNA hsa-miR-143:PITA hsa-miR-143:PITA_TOP PITA 1.30E-06 7.05E-03 2.62E-06 2.41E-05 14 220 "ADD3,FGF1,ELMOD1,PPM1E,AHCYL1,LHFPL4,CPLX2,CACNA1A,WSCD1,DCLK1,NSD2,PPP2R5C,CTNND1,WIPF2" MicroRNA hsa-miR-432:PITA hsa-miR-432:PITA_TOP PITA 1.34E-06 7.24E-03 2.69E-06 2.47E-05 12 160 "CCDC88A,EIF4G3,NEUROD1,EML4,VSTM2A,GRIA2,TUB,NSD2,ARHGEF4,ABI1,RASGRF1,EPB41" MicroRNA hsa-miR-628-3p:PITA hsa-miR-628-3p:PITA_TOP PITA 1.34E-06 7.24E-03 2.69E-06 2.47E-05 12 160 "SYT4,GPM6A,PTBP2,EML4,PCDH9,RBFOX2,HEPACAM,NEGR1,BTF3L4,PPP3CB,DLG2,PAK5" MicroRNA hsa-miR-23b-3p:Functional MTI Functional MTI miRTarbase 1.34E-06 7.24E-03 2.69E-06 2.47E-05 17 322 "ADD3,NLGN4X,EMC1,ERBIN,GANAB,ZEB1,TPM3,HNRNPK,CRLS1,VCAN,PRKACB,CSDE1,RAB5B,BSDC1,SLC6A15,JMJD1C,EN2" MicroRNA hsa-miR-187:mirSVR_highEffct hsa-miR-187:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.38E-06 7.48E-03 2.78E-06 2.55E-05 13 190 "MDM4,TESK2,NAXD,DKK3,WDTC1,FAM168A,GLS,GRIA2,TJP1,C1orf94,CNRIP1,BDNF-AS,RAB5B" MicroRNA hsa-miR-491-5p:PITA hsa-miR-491-5p:PITA_TOP PITA 1.39E-06 7.51E-03 2.79E-06 2.56E-05 10 107 "ARID1A,MYT1L,KIF21B,BCL2L2,CAMTA1,NRXN2,MAGI2,KCND3,SRGAP3,EFNA3" MicroRNA hsa-miR-10b-5p:Functional MTI Functional MTI miRTarbase 1.40E-06 7.56E-03 2.81E-06 2.58E-05 17 323 "ACLY,FOXRED2,ANXA7,API5,URGCP,SCMH1,SON,DDHD2,ZEB1,PAX6,TPM4,CADM1,PIK3CD,PPP3CB,IGSF1,PSMD13,OLFM3" MicroRNA hsa-miR-1268:mirSVR_highEffct hsa-miR-1268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-06 7.62E-03 2.83E-06 2.60E-05 11 133 "CSMD3,ITSN1,CGREF1,SEPT3,CDK5R2,PRMT8,A2ML1,KCNA2,TMCC2,ARHGEF10L,RNF220" MicroRNA hsa-miR-4313:mirSVR_highEffct hsa-miR-4313:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-06 7.84E-03 2.91E-06 2.67E-05 14 222 "RUFY2,MT3,ZSWIM8,FXYD6,NASP,TBX15,BRSK2,ZNF384,SLC25A27,BTF3L4,PRKCZ,USP54,PTPRE,CAMK1G" MicroRNA hsa-miR-130a-3p:Functional MTI Functional MTI miRTarbase 1.46E-06 7.93E-03 2.94E-06 2.70E-05 19 398 "ADARB2,CLIP1,CAPRIN2,SOX5,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,CEP170,WIPF2,RAB5B,DNM2,ARHGAP12" MicroRNA "TCATCTC,MIR-143:MSigDB" "TCATCTC,MIR-143:MSigDB" MSigDB 1.52E-06 8.20E-03 3.04E-06 2.79E-05 11 134 "ADD3,FGF1,ELMOD1,PPM1E,AHCYL1,SEPT3,PSD3,NEURL1,PC,TPM3,CTNND1" MicroRNA hsa-miR-208b-3p:TargetScan hsa-miR-208b-3p TargetScan 1.52E-06 8.25E-03 3.06E-06 2.80E-05 12 162 "FOXG1,APC,AHCYL1,PTBP2,EML4,PPP3CB,ANKS1B,HP1BP3,NAV2,KCNN3,ABI1,ELAVL4" MicroRNA hsa-miR-639:mirSVR_highEffct hsa-miR-639:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-06 8.25E-03 3.06E-06 2.80E-05 12 162 "NLGN4X,SMARCE1,WDTC1,DDR1,ZEB1,GRIA4,CDC42,HNRNPK,CRLS1,MICAL2,CNIH3,BLOC1S6" MicroRNA hsa-miR-208a-3p:TargetScan hsa-miR-208a-3p TargetScan 1.52E-06 8.25E-03 3.06E-06 2.80E-05 12 162 "FOXG1,APC,AHCYL1,PTBP2,EML4,PPP3CB,ANKS1B,HP1BP3,NAV2,KCNN3,ABI1,ELAVL4" MicroRNA hsa-miR-487b:mirSVR_highEffct hsa-miR-487b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.52E-06 8.25E-03 3.06E-06 2.80E-05 12 162 "CLIP1,NLGN4X,AMPH,ITSN1,MAGI3,GRIA2,GRIA4,GRM3,ZMYND8,SLC25A27,CADM2,PAK5" MicroRNA hsa-miR-24:PITA hsa-miR-24:PITA_TOP PITA 1.53E-06 8.27E-03 3.06E-06 2.81E-05 14 223 "WDTC1,BCL2L2,NEUROD1,SEMA4A,ACSL6,MAGI1,SNCAIP,USP54,PTPRD,KCNK2,DLG2,RAB5B,SFXN5,RAVER2" MicroRNA "GTATGAT,MIR-154:MSigDB" "GTATGAT,MIR-154:MSigDB" MSigDB 1.54E-06 8.35E-03 3.09E-06 2.83E-05 8 63 "ARID1A,CSMD3,GAD2,GPM6A,IFFO1,MAGI2,KCNMA1,RNF220" MicroRNA "GTATGAT,MIR-487:MSigDB" "GTATGAT,MIR-487:MSigDB" MSigDB 1.54E-06 8.35E-03 3.09E-06 2.83E-05 8 63 "ARID1A,CSMD3,GAD2,GPM6A,IFFO1,MAGI2,KCNMA1,RNF220" MicroRNA "AGGAGTG,MIR-483:MSigDB" "AGGAGTG,MIR-483:MSigDB" MSigDB 1.54E-06 8.35E-03 3.09E-06 2.83E-05 8 63 "FHL1,PKNOX2,SON,CAMK2G,NSD2,MED1,PHACTR3,RCAN2" MicroRNA hsa-miR-3173-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-06 8.83E-03 3.26E-06 2.99E-05 11 135 "ARID1A,RUFY2,NDUFA5,GJB1,FAM168A,ASTN2,TPM3,BSDC1,SSPN,CACNG7,EN2" MicroRNA "TTGGAGA,MIR-519E:MSigDB" "TTGGAGA,MIR-519E:MSigDB" MSigDB 1.63E-06 8.83E-03 3.26E-06 2.99E-05 11 135 "ARID1A,ITSN1,SNAP25,GABBR1,CAB39,ZFP91,MAEL,NSD2,OSBPL3,PUM1,EFNA3" MicroRNA "TTGGAGA,MIR-515-5P:MSigDB" "TTGGAGA,MIR-515-5P:MSigDB" MSigDB 1.63E-06 8.83E-03 3.26E-06 2.99E-05 11 135 "ARID1A,ITSN1,SNAP25,GABBR1,CAB39,ZFP91,MAEL,NSD2,OSBPL3,PUM1,EFNA3" MicroRNA hsa-miR-23a*:mirSVR_highEffct hsa-miR-23a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-06 8.85E-03 3.27E-06 3.00E-05 19 401 "ACLY,RUFY2,CGREF1,RCOR3,ATP1A2,PALLD,GNAS,CDC42,PADI2,PDYN,PLXNB3,CNTN1,MICAL2,NRSN1,SIRPA,KCNJ9,PCDH15,PYGM,PLEKHB2" MicroRNA hsa-miR-645:PITA hsa-miR-645:PITA_TOP PITA 1.64E-06 8.85E-03 3.27E-06 3.00E-05 9 85 "PPM1E,PHYHIPL,ZSWIM8,TCF12,ZFP91,PPP3CB,PUM1,LRRTM3,KCNK2" MicroRNA hsa-miR-337-3p:PITA hsa-miR-337-3p:PITA_TOP PITA 1.65E-06 8.91E-03 3.29E-06 3.02E-05 13 193 "LDLRAD3,SORCS1,NTNG1,CCDC88A,NCAM1,PCDH11X,CAMTA1,CAMK2G,ACBD5,CTNND2,PUM1,SLC17A6,ABI1" MicroRNA hsa-miR-604:PITA hsa-miR-604:PITA_TOP PITA 1.67E-06 9.06E-03 3.34E-06 3.07E-05 6 29 "CAMK2G,GRIA4,DCLK1,MED1,RIMS4,PIANP" MicroRNA hsa-miR-873:PITA hsa-miR-873:PITA_TOP PITA 1.70E-06 9.19E-03 3.39E-06 3.11E-05 14 225 "RTN3,NLGN4X,TACC2,NEUROD1,CAMTA1,PSD3,PADI2,HRH3,TPM4,HNRNPK,CADM1,FAT3,ACBD5,CA10" MicroRNA "CATGTAA,MIR-496:MSigDB" "CATGTAA,MIR-496:MSigDB" MSigDB 1.73E-06 9.39E-03 3.46E-06 3.17E-05 12 164 "SEMA6A,NSG2,ASCL1,MYT1L,CLASP2,NEUROD1,CAMTA1,GRIA2,NXPH1,TOX,PTHLH,RNF220" MicroRNA hsa-miR-3141:mirSVR_lowEffct hsa-miR-3141:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-06 9.40E-03 3.46E-06 3.18E-05 21 481 "RTN3,TUBB4A,ASIC4,ST3GAL3,LGI3,DLL3,RCOR3,NRG3,GRIN1,LINC00839,TMEM9,ARHGAP19,ASIC3,GDAP1L1,CELF5,PACSIN1,CTNND1,ELMO1,SMG7,PHC2,SEZ6" MicroRNA hsa-miR-548c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-06 9.55E-03 3.52E-06 3.23E-05 22 522 "SDE2,CCDC80,IGSF9B,EIF4G3,SON,MYBPC1,LUZP2,CACNA1A,EML4,TJP1,TLL2,CCSER2,FAT3,CTNND1,PTCH1,ITGAV,PRDM2,KCNN3,RAB5B,NUP214,ELAVL4,EN2" MicroRNA hsa-miR-665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-06 9.82E-03 3.62E-06 3.32E-05 27 737 "SLC30A10,MAGI3,SFMBT2,SLC2A5,PKNOX2,ATM,KIF21B,ACSBG1,ZNF638,GNG3,GNG4,NRGN,NUCB1,AKNA,TMEM9,TPM3,FAT3,ACBD5,MFSD4A,DOCK7,KIAA0513,HP1BP3,SNX27,DNAH9,DNM2,PLEKHB2,SYT15" MicroRNA hsa-miR-608:Functional MTI Functional MTI miRTarbase 1.85E-06 9.99E-03 3.68E-06 3.37E-05 13 195 "MDM4,PNMA8B,FOXRED2,KIAA1614,NKX2-2,CECR2,CDC42,TPM3,DLGAP3,UBTF,SPATA6,PACSIN1,MAPK10" MicroRNA hsa-miR-6794-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-06 1.00E-02 3.68E-06 3.38E-05 12 165 "EMID1,MDM4,WAC,SESN3,SON,WDTC1,NMNAT2,NDUFA5,CCSER2,PTPA,BDNF-AS,EPB41L1" MicroRNA hsa-miR-1266:PITA hsa-miR-1266:PITA_TOP PITA 1.88E-06 1.02E-02 3.75E-06 3.44E-05 11 137 "CSMD2,ARID1A,SORCS1,CNIH2,EIF4G3,BCL2L2,CAMTA1,CAMSAP2,CELF3,CAMKV,MED1" MicroRNA hsa-miR-455-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-06 1.04E-02 3.81E-06 3.50E-05 28 784 "PLEKHG5,SLC30A10,MOBP,MAGI3,CCDC80,CLSTN1,SLC1A2,KBTBD12,SCN3B,SON,KIF21B,NASP,GNG4,ZEB1,PTBP2,NUCB1,RFFL,KCNK10,TPM3,SCRG1,JAM2,CCSER2,FAT3,ACBD5,PLPP4,RIMS3,HP1BP3,DNAH9" MicroRNA hsa-miR-324-5p:TargetScan hsa-miR-324-5p TargetScan 1.94E-06 1.05E-02 3.86E-06 3.54E-05 10 111 "CDC42BPA,FYN,KAZN,GRIK3,RBFOX2,CAMKV,NCAN,KIAA0513,GON4L,PTPRD" MicroRNA hsa-miR-4311:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-06 1.06E-02 3.89E-06 3.56E-05 13 196 "MAG,ADCYAP1R1,WAC,SGIP1,CDC42BPA,CCDC88A,SON,NFIA,DCLK2,CECR2,TPD52,PLD5,ZNF248" MicroRNA hsa-miR-6875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-06 1.06E-02 3.90E-06 3.58E-05 15 261 "CACHD1,ASCL1,ATP1A2,SMOC1,NODAL,ACSL6,GRIK3,CDH8,FNDC5,NEGR1,TENM4,JMJD1C,SH3GLB1,ABI2,ELAVL3" MicroRNA hsa-miR-325:PITA hsa-miR-325:PITA_TOP PITA 1.96E-06 1.06E-02 3.91E-06 3.58E-05 8 65 "SLC1A2,SOX5,DNER,GPM6A,GRIA4,CCSER2,ACBD5,TTLL7" MicroRNA hsa-miR-518b:mirSVR_highEffct hsa-miR-518b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-06 1.07E-02 3.91E-06 3.59E-05 12 166 "TTYH1,FHL1,TACC2,NSG2,NDUFA5,TGFBR3,LGI1,CHGA,PPP3CB,PRDM2,TMEM255A,PARP11" MicroRNA "GGCAGTG,MIR-324-3P:MSigDB" "GGCAGTG,MIR-324-3P:MSigDB" MSigDB 1.99E-06 1.08E-02 3.95E-06 3.63E-05 9 87 "MBP,SORCS1,SFPQ,ST3GAL3,SHANK2,SEMA5B,PRKACB,RIMS3,SRGAP3" MicroRNA hsa-miR-876-5p:TargetScan hsa-miR-876-5p TargetScan 2.09E-06 1.13E-02 4.14E-06 3.80E-05 14 229 "RIMKLA,ADARB2,ANK1,CELF3,PAX6,PDE3B,NEGR1,COL9A2,MED1,MAGI2,PTPRD,KCNN3,ABI2,EN2" MicroRNA hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 2.10E-06 1.13E-02 4.16E-06 3.81E-05 16 297 "FAM43B,ARID1A,ADORA3,ANXA7,CACHD1,USP16,ARFGAP2,ADGRB2,GANAB,PCDH11X,TCF7L2,PMS2,NSD2,PUM1,KIAA0408,ARHGEF10L" MicroRNA hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA_TOP PITA 2.10E-06 1.14E-02 4.16E-06 3.81E-05 12 167 "SDE2,SOX6,ZCCHC24,SYT4,NKX2-2,TCF12,GRIN1,CDC42,CADM1,CTNND2,WBP1L,DSCAM" MicroRNA hsa-miR-4716-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-06 1.14E-02 4.16E-06 3.81E-05 12 167 "EMID1,MDM4,WAC,SESN3,SON,WDTC1,NMNAT2,NDUFA5,CCSER2,PTPA,BDNF-AS,EPB41L1" MicroRNA hsa-miR-7160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-06 1.14E-02 4.18E-06 3.83E-05 21 487 "TTYH1,SFMBT2,SLC2A5,ATM,WDTC1,ZNF638,PTBP2,AKNA,TPM3,GPR37L1,MFSD4A,KIAA0408,KIAA0513,TOMM20,SNX27,WIPF2,DNAH9,RAB5B,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-6891-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-06 1.18E-02 4.31E-06 3.95E-05 11 139 "ARID1A,RUFY2,NDUFA5,GJB1,FAM168A,ASTN2,TPM3,BSDC1,SSPN,CACNG7,EN2" MicroRNA hsa-miR-6733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.18E-02 4.33E-06 3.97E-05 13 198 "WAC,SESN3,JAKMIP3,RPH3A,YPEL4,ZFP91,NEGR1,POU3F2,WBP1L,BDNF-AS,DPP6,GPR61,BSCL2" MicroRNA hsa-miR-3153:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.18E-02 4.33E-06 3.97E-05 13 198 "WAC,SESN3,JAKMIP3,RPH3A,YPEL4,ZFP91,NEGR1,POU3F2,WBP1L,BDNF-AS,DPP6,GPR61,BSCL2" MicroRNA "GAGACTG,MIR-452:MSigDB" "GAGACTG,MIR-452:MSigDB" MSigDB 2.19E-06 1.19E-02 4.34E-06 3.98E-05 9 88 "SLC6A9,BCL2L2,TCF12,DCLK1,SLC25A27,PRRX1,NXPH1,SNX27,SH3GLB1" MicroRNA hsa-miR-5589-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.19E-02 4.34E-06 3.98E-05 17 334 "FOXRED2,DRAXIN,CCDC80,EMC1,BCL2L2,WWC1,GRIK3,MFSD2A,HMGB1,BTF3L4,SPATA6,NSD2,OCIAD1,KCND3,RABGAP1L,RAB5B,ABI2" MicroRNA hsa-miR-3689a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-06 1.21E-02 4.42E-06 4.05E-05 25 657 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-3689c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-06 1.21E-02 4.42E-06 4.05E-05 25 657 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-3689b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-06 1.21E-02 4.42E-06 4.05E-05 25 657 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 2.28E-06 1.24E-02 4.51E-06 4.14E-05 16 299 "EXTL1,AMER2,AQP4,CADM3,KIF1B,BCL2L2,PSRC1,ACSL6,RFFL,PAX6,ARHGAP19,FNDC5,MAGI2,KCND3,DTNA,EPB41L2" MicroRNA hsa-miR-1306-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-06 1.25E-02 4.57E-06 4.19E-05 13 199 "RIMKLA,JAKMIP3,ATM,CPLX2,SMOC1,INKA2,GJB1,PCDH11X,SCRG1,A2ML1,RNF14,ZBTB16,KCND3" MicroRNA "TCTGATC,MIR-383:MSigDB" "TCTGATC,MIR-383:MSigDB" MSigDB 2.34E-06 1.26E-02 4.61E-06 4.23E-05 7 47 "SORCS1,SOX5,IDI2-AS1,NEUROD1,DCLK1,NXPH1,BLOC1S6" MicroRNA hsa-miR-1273h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.36E-06 1.28E-02 4.65E-06 4.27E-05 25 659 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-6780a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-06 1.31E-02 4.77E-06 4.38E-05 25 660 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-150:PITA hsa-miR-150:PITA_TOP PITA 2.44E-06 1.32E-02 4.82E-06 4.42E-05 13 200 "TESK2,PPM1E,APC,RAP1GAP2,NKX2-2,ZEB1,NLGN3,SEMA5B,NEGR1,FTO,PTCH1,KCNN3,EPB41" MicroRNA hsa-miR-877:PITA hsa-miR-877:PITA_TOP PITA 2.48E-06 1.34E-02 4.88E-06 4.48E-05 10 114 "SCN3A,FOXM1,AMPH,AHCYL1,NMNAT2,NEURL1,NMT2,BRINP3,PTCH1,TMCC2" MicroRNA "CTCAGGG,MIR-125B:MSigDB" "CTCAGGG,MIR-125B:MSigDB" MSigDB 2.49E-06 1.35E-02 4.90E-06 4.50E-05 16 301 "MAP6,ASIC1,EMID1,MADD,SLC8A2,DIRAS1,PPP2R5C,FAM131B,MASP1,PHYHIP,CSDE1,GOPC,RET,PHC2,VANGL2,SLC4A10" MicroRNA "CTCAGGG,MIR-125A:MSigDB" "CTCAGGG,MIR-125A:MSigDB" MSigDB 2.49E-06 1.35E-02 4.90E-06 4.50E-05 16 301 "MAP6,ASIC1,EMID1,MADD,SLC8A2,DIRAS1,PPP2R5C,FAM131B,MASP1,PHYHIP,CSDE1,GOPC,RET,PHC2,VANGL2,SLC4A10" MicroRNA hsa-miR-412:PITA hsa-miR-412:PITA_TOP PITA 2.50E-06 1.35E-02 4.92E-06 4.51E-05 11 141 "SEMA6A,SOX6,PKP4,NLGN1,WDTC1,KIF21B,ERBIN,BTRC,CDH10,CSDE1,SMG7" MicroRNA hsa-miR-561-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-06 1.35E-02 4.92E-06 4.51E-05 11 141 "GALNT13,SESN3,CADPS,SON,CRB1,NEGR1,RBPJ,PTCH1,PMEPA1,SH3GLB1,RCAN2" MicroRNA hsa-miR-496:PITA hsa-miR-496:PITA_TOP PITA 2.52E-06 1.37E-02 4.97E-06 4.56E-05 12 170 "SCN3A,BCAR3,NLGN1,EIF4G3,MYT1L,NPAS3,NEUROD1,TMEFF2,NRXN2,PRTFDC1,KCNA6,SRGAP3" MicroRNA hsa-miR-301b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.54E-06 1.38E-02 5.00E-06 4.59E-05 18 375 "ADARB2,CLIP1,CAPRIN2,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,ZBTB16,CEP170,WIPF2,RAB5B,ARHGAP12" MicroRNA hsa-miR-891a:mirSVR_lowEffct hsa-miR-891a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-06 1.39E-02 5.06E-06 4.65E-05 17 338 "CHST15,FGF1,SEMA6A,NTNG1,MIER1,ZNF638,VSTM2A,CRB1,A2ML1,IFFO1,MICAL2,PCDH15,CAB39L,CAMK1G,SYT15,ELAVL3,ELAVL4" MicroRNA hsa-miR-100:mirSVR_lowEffct hsa-miR-100:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-06 1.40E-02 5.08E-06 4.66E-05 13 201 "MOG,SLC8A2,SLC14A1,ALDH1L1,BEST3,BEST1,DOCK7,RAB39A,PRKCZ,EDRF1,PLPPR4,NTM,TTLL7" MicroRNA hsa-miR-33b*:mirSVR_highEffct hsa-miR-33b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-06 1.42E-02 5.16E-06 4.73E-05 23 577 "RTKN,WAC,HPCAL4,ANK3,PPFIA1,ITSN1,NTNG1,ATP1A2,USP33,NCAM1,RGL1,RND1,GLS,TCF12,NUMA1,BDNF-AS,KCNC1,DLG2,RAP1GAP,ABI1,SLC6A15,ZYG11B,EPB41" MicroRNA hsa-miR-134-5p:TargetScan hsa-miR-134-5p TargetScan 2.68E-06 1.45E-02 5.26E-06 4.82E-05 11 142 "RIMKLA,MRVI1,FAM168A,CNTN2,PSD3,GRIK2,GRIK3,HPSE2,JAKMIP2,PIANP,ABI2" MicroRNA hsa-miR-711:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-06 1.46E-02 5.31E-06 4.87E-05 7 48 "TTYH1,ECSIT,GPR26,CYB561A3,NCAN,FGFR1OP2,DNM2" MicroRNA hsa-miR-3139:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-06 1.51E-02 5.46E-06 5.01E-05 8 68 "PLEKHG5,TUBB4A,DRAXIN,FAM168A,ZFP91,NOS1AP,PRDM2,PIANP" MicroRNA hsa-miR-93-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-06 1.54E-02 5.58E-06 5.12E-05 15 269 "ACLY,TESK2,ARFGAP1,FYN,NASP,GPR162,NEUROD1,GANAB,GRIK3,CDC42,PDYN,KIAA1549L,TOMM20,PSMD13,ELAVL3" MicroRNA hsa-miR-548az-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-06 1.54E-02 5.58E-06 5.12E-05 15 269 "ATAT1,WAC,SESN3,SON,SALL3,SMOC1,GPM6A,PTBP2,PFKFB3,ST8SIA5,CADM2,CEP170,CSDE1,JMJD1C,ARHGAP12" MicroRNA hsa-miR-548t-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-06 1.54E-02 5.58E-06 5.12E-05 15 269 "ATAT1,WAC,SESN3,SON,SALL3,SMOC1,GPM6A,PTBP2,PFKFB3,ST8SIA5,CADM2,CEP170,CSDE1,JMJD1C,ARHGAP12" MicroRNA hsa-miR-219-5p:PITA hsa-miR-219-5p:PITA_TOP PITA 2.85E-06 1.54E-02 5.59E-06 5.13E-05 12 172 "EYA1,SOX6,NTNG1,SLC8A2,SOX5,ZCCHC24,ILDR2,KIF1B,CAMK2G,CNRIP1,DNAJC6,GPR61" MicroRNA hsa-miR-658:mirSVR_highEffct hsa-miR-658:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-06 1.56E-02 5.64E-06 5.18E-05 13 203 "YPEL4,MT3,CAPRIN2,CLASP2,NUMA1,PTPN5,SEZ6L,ZMYND8,KIAA1549L,NRXN2,FLRT1,SF1,UEVLD" MicroRNA hsa-miR-6779-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-06 1.58E-02 5.70E-06 5.23E-05 25 667 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-30b-3p:Functional MTI Functional MTI miRTarbase 2.91E-06 1.58E-02 5.70E-06 5.23E-05 25 667 "ADAR,SOX6,CLSTN1,SLC1A2,DNAH17,KBTBD12,ZCCHC24,TTLL9,GNG4,BEST3,SCRG1,PFKFB3,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,TOMM20,SNX27,RAB5B,PLEKHB2,PHC2,ABI2" MicroRNA hsa-miR-10b:PITA hsa-miR-10b:PITA_TOP PITA 3.03E-06 1.64E-02 5.93E-06 5.44E-05 12 173 "ITSN1,MYT1L,LHFPL4,UNC5D,BTRC,CAMK2G,MAGI1,HNRNPK,CADM1,MED1,INSYN2,ARHGAP12" MicroRNA hsa-miR-10a:PITA hsa-miR-10a:PITA_TOP PITA 3.03E-06 1.64E-02 5.93E-06 5.44E-05 12 173 "ITSN1,MYT1L,LHFPL4,UNC5D,BTRC,CAMK2G,MAGI1,HNRNPK,CADM1,MED1,INSYN2,ARHGAP12" MicroRNA hsa-miR-6739-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-06 1.65E-02 5.95E-06 5.46E-05 13 204 "WAC,SESN3,JAKMIP3,RPH3A,YPEL4,ZFP91,NEGR1,POU3F2,WBP1L,BDNF-AS,DPP6,GPR61,BSCL2" MicroRNA hsa-miR-7113-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.21E-06 1.74E-02 6.27E-06 5.75E-05 13 205 "SRARP,TACC2,GJB1,ZNF638,CACNA1A,GRID1,RFFL,ZDHHC22,CDH8,BEST3,SMG7,KCNH1,KCNJ11" MicroRNA hsa-miR-551b:mirSVR_lowEffct hsa-miR-551b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.26E-06 1.76E-02 6.37E-06 5.84E-05 15 272 "MBP,CSMD2,SCG3,TMEM136,CNDP1,NUMA1,NEURL1,ZFP91,JAM2,FAAP20,PNKD,DOCK7,CCDC3,SFXN5,ABI2" MicroRNA hsa-miR-589:PITA hsa-miR-589:PITA_TOP PITA 3.39E-06 1.83E-02 6.61E-06 6.07E-05 10 118 "GPR158,SEMA6A,UNC5D,CAMK2A,MAGI1,RGS6,PRKAB2,PKN2,DSCAM,ELAVL3" MicroRNA hsa-miR-220a:mirSVR_highEffct hsa-miR-220a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.39E-06 1.83E-02 6.61E-06 6.07E-05 10 118 "ZFYVE27,CSMD2,KLHL32,KIF1B,CACNA1E,DDR1,PRKCZ,PSMD13,OLFM3,KCNC1" MicroRNA hsa-miR-423-5p:PITA hsa-miR-423-5p:PITA_TOP PITA 3.39E-06 1.83E-02 6.61E-06 6.07E-05 10 118 "ASIC1,ACHE,MYT1L,CADM3,HAP1,CDC42,RIMS4,PUM1,SRGAP3,EFNA3" MicroRNA hsa-miR-4778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-06 1.85E-02 6.66E-06 6.11E-05 12 175 "RABEPK,CACHD1,ASCL1,TMEM151A,ATP1A2,NODAL,VXN,GRIK3,HMGB1,RABGAP1L,ST8SIA3,ABI2" MicroRNA hsa-miR-1294:PITA hsa-miR-1294:PITA_TOP PITA 3.41E-06 1.85E-02 6.66E-06 6.11E-05 12 175 "SCN4B,ZCCHC24,BCL2L2,SYT4,REPS2,CDH10,RBFOX2,PRRX1,SF1,RGS6,PTPRD,VANGL2" MicroRNA hsa-miR-654-3p:Functional MTI Functional MTI miRTarbase 3.47E-06 1.88E-02 6.77E-06 6.21E-05 8 70 "FOXG1,PTBP2,KCNK10,KIAA1549L,BTF3L4,SDC3,PMEPA1,BSDC1" MicroRNA hsa-miR-512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.48E-06 1.88E-02 6.79E-06 6.22E-05 16 309 "FOXRED2,DRAXIN,CAPRIN2,EMC1,BCL2L2,WWC1,MFSD2A,TPD52,HMGB1,CADM2,OCIAD1,KCND3,RABGAP1L,WIPF2,ABI2,BSCL2" MicroRNA "AACTGAC,MIR-223:MSigDB" "AACTGAC,MIR-223:MSigDB" MSigDB 3.49E-06 1.89E-02 6.79E-06 6.23E-05 9 93 "F3,SCN3A,SON,NFIA,PTBP2,UBTF,RBPJ,WBP1L,SRGAP3" MicroRNA hsa-miR-296-3p:PITA hsa-miR-296-3p:PITA_TOP PITA 3.49E-06 1.89E-02 6.79E-06 6.23E-05 9 93 "ERMN,CADPS,TCF12,GRM3,SERPINE2,PTCH1,JAKMIP2,DLG2,CALN1" MicroRNA hsa-miR-675:mirSVR_highEffct hsa-miR-675:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.49E-06 1.89E-02 6.79E-06 6.23E-05 9 93 "ATAT1,TUBB4A,KBTBD12,ADGRB2,CASTOR3,FBXL16,ZBTB16,HP1BP3,NKAIN1" MicroRNA hsa-miR-558:PITA hsa-miR-558:PITA_TOP PITA 3.51E-06 1.90E-02 6.82E-06 6.26E-05 11 146 "PDZD4,ANK1,NRGN,GRM3,RBFOX2,PDE4B,CADM1,NEGR1,KCNA1,SV2A,SNX27" MicroRNA hsa-miR-924:PITA hsa-miR-924:PITA_TOP PITA 3.51E-06 1.90E-02 6.82E-06 6.26E-05 11 146 "DSCAML1,CDC42BPA,API5,POPDC3,GUCY1A2,SERPINE2,CADM1,NRXN1,TENM4,DSCAM,RBM12" MicroRNA hsa-miR-1537:mirSVR_highEffct hsa-miR-1537:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.52E-06 1.90E-02 6.84E-06 6.28E-05 17 346 "AMPH,DOCK10,SORBS1,SHTN1,CAB39,TTLL9,LMO3,NDUFA5,ADHFE1,ZNF638,ADGRL3,MICAL2,ANKS1B,DBX2,DTNA,SLC6A15,RPRD1A" MicroRNA hsa-miR-4665-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.54E-06 1.92E-02 6.88E-06 6.31E-05 5 19 "NRGN,MEAF6,PLD5,OCIAD1,EPB41" MicroRNA hsa-miR-1249-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-06 1.93E-02 6.92E-06 6.35E-05 15 274 "DPF1,RTN3,WAC,SESN3,CLSTN1,TTLL9,ASTN2,HAP1,ZFP91,BTF3L4,KIAA0513,NAV2,PARP11,SYT15,EPB41L1" MicroRNA hsa-miR-342-5p:mirSVR_highEffct hsa-miR-342-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.65E-06 1.98E-02 7.10E-06 6.52E-05 17 347 "ACLY,MEG3,ATAT1,KCNIP2,PDZD4,PAAF1,NFASC,AJAP1,CASTOR3,GNG3,DDR1,PLEKHB1,PRKCG,KCNK2,TMEM255A,DTNA,SEC61A2" MicroRNA hsa-miR-4649-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-06 2.00E-02 7.18E-06 6.59E-05 21 505 "SDE2,ARID1A,TOMM40L,SFMBT2,SLC2A5,ATM,KIF1B,ZNF638,PTBP2,NUCB1,AKNA,TPM3,GPR37L1,MFSD4A,KIAA0408,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-3193:mirSVR_highEffct hsa-miR-3193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.75E-06 2.03E-02 7.28E-06 6.68E-05 11 147 "LGR4,ARPP21,CACNB2,EML4,LRTM2,PLXNB3,BTF3L4,MED1,SNCAIP,ZBTB16,UEVLD" MicroRNA hsa-miR-4290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.81E-06 2.06E-02 7.40E-06 6.79E-05 9 94 "APC2,F3,ZCCHC24,NFASC,GPR26,HPR,TENM4,RGS6,KCNH1" MicroRNA "ACTGTAG,MIR-139:MSigDB" "ACTGTAG,MIR-139:MSigDB" MSigDB 3.94E-06 2.13E-02 7.65E-06 7.02E-05 10 120 "ANK2,ATP2B2,SOX1,SOX5,TCF12,FBXL16,CDC42,NXPH1,PPP3CB,PAK5" MicroRNA hsa-miR-6797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-06 2.20E-02 7.88E-06 7.23E-05 15 277 "DPF1,RTN3,WAC,SESN3,CLSTN1,TTLL9,ASTN2,HAP1,ZFP91,BTF3L4,KIAA0513,NAV2,PARP11,SYT15,EPB41L1" MicroRNA hsa-miR-3192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-06 2.20E-02 7.88E-06 7.23E-05 15 277 "KBTBD12,ZCCHC24,AJAP1,BEST3,SCRG1,CHRNB2,NEGR1,VAV2,BTF3L4,COL9A2,ATCAY,MFSD4A,PTPA,RGS6,SYT15" MicroRNA hsa-miR-523:mirSVR_lowEffct hsa-miR-523:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.16E-06 2.25E-02 8.07E-06 7.40E-05 9 95 "ADGRV1,ECSIT,ATAT1,GRAMD1B,RASA3,ST3GAL3,SLCO1A2,CAMK2A,PIK3CD" MicroRNA hsa-miR-6778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-06 2.26E-02 8.08E-06 7.41E-05 25 681 "FOXRED2,DRAXIN,TESK2,MOG,SLC7A14,INKA2,AJAP1,WWC1,CACNA1A,ACSL6,TMEM151B,MFSD2A,P2RX7,GPR37L1,HMGB1,COL9A2,ATCAY,KIAA0408,ZBTB16,PTAFR,OCIAD1,RABGAP1L,WIPF2,PLEKHO1,EPB41L1" MicroRNA hsa-miR-4251:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-06 2.30E-02 8.23E-06 7.55E-05 10 121 "MRVI1,KCNIP2,PLEKHG5,KLHL32,MIER1,TMEM136,NUCB1,PRMT8,MICAL2,PRKAB2" MicroRNA hsa-miR-885-3p:mirSVR_highEffct hsa-miR-885-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.27E-06 2.31E-02 8.27E-06 7.59E-05 11 149 "ARID1A,SCMH1,ZSWIM8,CACNB2,SEZ6L,PRMT8,PPP3CB,RGS6,WBP1L,SEC61A2,RAVER2" MicroRNA hsa-miR-512-5p:mirSVR_highEffct hsa-miR-512-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.29E-06 2.32E-02 8.31E-06 7.62E-05 24 638 "MAG,MOG,SMARCE1,AHCYL1,BCL2L2,ZNF638,PTBP2,GRM3,CHRM1,HPR,DNAJC12,BTF3L4,VCAN,RBPJ,NRSN1,EDRF1,PTPRZ1,CCDC3,PEX5,PID1,FAM66C,DBX2,VWA5A,RPE65" MicroRNA hsa-miR-1298:PITA hsa-miR-1298:PITA_TOP PITA 4.48E-06 2.43E-02 8.68E-06 7.96E-05 6 34 "YPEL4,ATP2B2,DNER,NCAM1,LRRTM3,SRGAP3" MicroRNA hsa-miR-423-3p:mirSVR_highEffct hsa-miR-423-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-06 2.48E-02 8.84E-06 8.11E-05 10 122 "SMARCE1,DKK3,WDTC1,NCAM1,CAMK2A,MFSD2A,CMTM5,KCNN3,DTNA,SLC6A15" MicroRNA hsa-miR-887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.59E-06 2.49E-02 8.88E-06 8.14E-05 20 471 "MDM4,SOX6,CLSTN1,SLC1A2,SLC6A9,DNAH17,GNG4,GRIK2,ZFP91,FTO,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,SNX27,DNAH9,RAB5B,PLEKHB2,ABI2" MicroRNA hsa-miR-125a-5p:mirSVR_highEffct hsa-miR-125a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.59E-06 2.49E-02 8.88E-06 8.14E-05 20 471 "CNIH2,BCAN,SHTN1,CGREF1,ASPH,ATM,USP2,AIFM1,SULT4A1,C11orf49,MICAL2,MASP1,STMN4,RABGAP1L,KCNK2,KCNMA1,KLRC2,RASGRF1,SEC61A2,SLC4A10" MicroRNA hsa-miR-1231:PITA hsa-miR-1231:PITA_TOP PITA 4.85E-06 2.63E-02 9.38E-06 8.61E-05 11 151 "FGF14,AMPH,NTNG1,GPAM,RCOR3,BTRC,GPR88,REPS2,PACSIN1,SF1,KCNA1" MicroRNA hsa-miR-101-3p:Functional MTI Functional MTI miRTarbase 4.86E-06 2.63E-02 9.40E-06 8.62E-05 18 393 "EYA1,ARID1A,CDC7,GPAM,ATM,BTRC,ZEB1,GRIK3,TGFBR3,INA,CD81,CADM1,PIK3CD,SPIRE1,BLOC1S6,ZC3H11A,RTN4,ELAVL3" MicroRNA hsa-miR-486-5p:TargetScan hsa-miR-486-5p TargetScan 4.92E-06 2.66E-02 9.50E-06 8.71E-05 10 123 "ARHGAP5,GPR153,CSPG5,RFFL,GUCY1A2,CADM1,FAT3,PPP3CB,RBM12,EPB41L1" MicroRNA hsa-miR-933:mirSVR_highEffct hsa-miR-933:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.95E-06 2.68E-02 9.55E-06 8.76E-05 9 97 "SCN3A,CAMK2G,GRIA2,LINC00839,TMEM25,MAGI1,HERC2P3,RPE65,RCAN2" MicroRNA "ACACTAC,MIR-142-3P:MSigDB" "ACACTAC,MIR-142-3P:MSigDB" MSigDB 5.29E-06 2.86E-02 1.02E-05 9.36E-05 10 124 "ANK3,PPFIA1,APC,EML4,PDE4B,HMGB1,PUM1,ITGAV,COPS7A,ATG16L1" MicroRNA hsa-miR-6128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-06 2.92E-02 1.04E-05 9.53E-05 9 98 "NLGN4X,TMEM151A,GNAS,NUDT21,RIMS4,C1orf109,ABI2,BSCL2,EPB41" MicroRNA hsa-miR-4319:mirSVR_highEffct hsa-miR-4319:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.46E-06 2.96E-02 1.05E-05 9.67E-05 19 436 "CNIH2,BCAN,SHTN1,CGREF1,ASPH,ATM,USP2,AIFM1,SULT4A1,MICAL2,MASP1,STMN4,RABGAP1L,KCNMA1,KLRC2,RASGRF1,SLC6A15,SEC61A2,SLC4A10" MicroRNA hsa-miR-663b:mirSVR_highEffct hsa-miR-663b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-06 2.97E-02 1.06E-05 9.71E-05 15 284 "CSMD2,GALNT13,TMEM156,ERICH3,EMC1,FXYD6,GRIA2,LEFTY2,TPD52,CSF3R,ATRNL1,RBPJ,KLK6,OLFM3,RFX5" MicroRNA hsa-miR-551a:mirSVR_lowEffct hsa-miR-551a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.49E-06 2.97E-02 1.06E-05 9.71E-05 15 284 "MBP,CSMD2,CLSTN1,SCG3,TMEM136,CNDP1,NEURL1,PDE4B,JAM2,FAAP20,PNKD,DOCK7,CCDC3,SFXN5,ABI2" MicroRNA "ATTACAT,MIR-380-3P:MSigDB" "ATTACAT,MIR-380-3P:MSigDB" MSigDB 5.86E-06 3.17E-02 1.13E-05 1.04E-04 9 99 "SNAP25,KLHL4,KCNK10,NRXN1,BRINP3,LRRTM3,ITGAV,SLC6A15,EPB41L1" MicroRNA "AGGGCCA,MIR-328:MSigDB" "AGGGCCA,MIR-328:MSigDB" MSigDB 5.86E-06 3.17E-02 1.13E-05 1.04E-04 8 75 "LGR4,TESK2,SLITRK3,ST3GAL3,WDTC1,SEPT3,GPM6A,HAP1" MicroRNA hsa-miR-1292:mirSVR_highEffct hsa-miR-1292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-06 3.30E-02 1.18E-05 1.08E-04 10 126 "ADGRV1,ITSN1,ZNF365,GAD2,KIF1B,PCSK2,CNTN1,EDRF1,KCNMA1,CAB39L" MicroRNA hsa-miR-6884-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-06 3.32E-02 1.18E-05 1.08E-04 21 522 "MDM4,PNMA8B,SLC2A5,SLIT1,ATM,WDTC1,RAP1GAP2,ZNF638,BTRC,AKNA,TPM3,MFSD4A,RIMS4,KIAA0408,PSD,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-886-5p:mirSVR_lowEffct hsa-miR-886-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.16E-06 3.33E-02 1.18E-05 1.09E-04 17 361 "TTYH1,TUBB4A,ASIC4,SLC30A10,SLC2A5,SLC6A9,MT3,ADAM15,ACSBG1,NKX2-2,GNG3,VSTM2A,GRIN1,SEZ6L,TJP2,KCNA6,OLIG2" MicroRNA hsa-miR-4779:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.23E-06 3.37E-02 1.20E-05 1.10E-04 15 287 "DPF1,SLIT1,KIF21B,NDUFA5,GJB1,FAM168A,ASTN2,TPM3,FTO,KIAA0513,NAV2,PARP11,SSPN,EN2,EPB41L1" MicroRNA hsa-miR-3650:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-06 3.38E-02 1.20E-05 1.10E-04 11 155 "BCAS1,RPH3A,SLC2A5,FAM69C,TMEM151B,TPD52,KIAA1549L,SPATA6,MAPK10,RAB5B,EN2" MicroRNA hsa-miR-503:mirSVR_highEffct hsa-miR-503:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.24E-06 3.38E-02 1.20E-05 1.10E-04 11 155 "ACHE,FCGR1A,ANK3,MSR1,DACH2,SEPT3,DDHD2,TCF7L2,FEZ1,KCND3,TMEM100" MicroRNA hsa-miR-661:PITA hsa-miR-661:PITA_TOP PITA 6.24E-06 3.38E-02 1.20E-05 1.10E-04 11 155 "SDE2,APBA2,NUMA1,ZFP91,NRXN2,RIMS4,ARHGEF4,SNX27,PHC2,EEF1A2,ELAVL3" MicroRNA hsa-miR-1243:PITA hsa-miR-1243:PITA_TOP PITA 6.24E-06 3.38E-02 1.20E-05 1.10E-04 11 155 "EYA1,ARID1A,NEUROD1,GRIA2,OPCML,CDC42,PCDH9,NLGN3,SEMA5B,DNAJC6,MAGI2" MicroRNA "ACTGCAG,MIR-17-3P:MSigDB" "ACTGCAG,MIR-17-3P:MSigDB" MSigDB 6.36E-06 3.44E-02 1.22E-05 1.12E-04 9 100 "SLITRK1,ITSN1,SHTN1,USP33,NRDC,CSDE1,KCNMA1,SNX27,NKAIN1" MicroRNA hsa-miR-455-5p:TargetScan hsa-miR-455-5p TargetScan 6.38E-06 3.46E-02 1.22E-05 1.12E-04 12 186 "ARID1A,GALNT13,ADD3,KIF1B,NPAS3,DCAF5,NRXN1,NMT2,NXPH1,RIMS4,CTNND1,ABI2" MicroRNA hsa-miR-553:mirSVR_highEffct hsa-miR-553:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.41E-06 3.47E-02 1.23E-05 1.13E-04 18 401 "SDE2,CLIP1,SORCS1,AMER2,CDC42BPA,NLGN1,JAKMIP3,SLIT1,GPM6B,PTBP2,GPR88,CDC42,CDH10,FAM181B,NSD2,MED1,FMN2,CA10" MicroRNA hsa-miR-3916:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-06 3.65E-02 1.29E-05 1.19E-04 12 187 "PRR5L,CCDC80,SFMBT2,SON,CECR2,DDR2,ZFP91,BTF3L4,CTNND1,WIPF2,DNM2,C12orf4" MicroRNA "TGCACTG,MIR-152:MSigDB" "TGCACTG,MIR-152:MSigDB" MSigDB 6.77E-06 3.67E-02 1.30E-05 1.19E-04 15 289 "PRR5L,ADCY2,ANK2,MIER1,LRRC55,USP33,DNER,GPM6A,CAMK2A,NSD2,POU3F2,ELMO1,RGMA,SNX27,ST8SIA3" MicroRNA "TGCACTG,MIR-148B:MSigDB" "TGCACTG,MIR-148B:MSigDB" MSigDB 6.77E-06 3.67E-02 1.30E-05 1.19E-04 15 289 "PRR5L,ADCY2,ANK2,MIER1,LRRC55,USP33,DNER,GPM6A,CAMK2A,NSD2,POU3F2,ELMO1,RGMA,SNX27,ST8SIA3" MicroRNA "TGCACTG,MIR-148A:MSigDB" "TGCACTG,MIR-148A:MSigDB" MSigDB 6.77E-06 3.67E-02 1.30E-05 1.19E-04 15 289 "PRR5L,ADCY2,ANK2,MIER1,LRRC55,USP33,DNER,GPM6A,CAMK2A,NSD2,POU3F2,ELMO1,RGMA,SNX27,ST8SIA3" MicroRNA hsa-miR-3666:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.86E-06 3.71E-02 1.31E-05 1.21E-04 17 364 "ADARB2,CLIP1,CAPRIN2,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,CEP170,WIPF2,RAB5B,ARHGAP12" MicroRNA hsa-miR-885-3p:PITA hsa-miR-885-3p:PITA_TOP PITA 6.89E-06 3.73E-02 1.32E-05 1.21E-04 7 55 "CELF3,TNS1,PPP3CB,RIMS4,L1CAM,SEC61A2,RAVER2" MicroRNA hsa-miR-655-3p:Functional MTI Functional MTI miRTarbase 6.90E-06 3.74E-02 1.32E-05 1.21E-04 9 101 "SESN3,CAPRIN2,CAMSAP2,ZEB1,GPR26,PSD3,PRRX1,SPIRE1,MAGI2" MicroRNA hsa-miR-296-5p:mirSVR_highEffct hsa-miR-296-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.92E-06 3.75E-02 1.32E-05 1.21E-04 13 220 "TOMM40L,NTNG1,SPHKAP,TMEM151A,SOX10,LMO3,BCL2L2,AKNA,PLPPR5,SMG7,KCNQ2,PHC2,RBM12" MicroRNA hsa-miR-502-5p:PITA hsa-miR-502-5p:PITA_TOP PITA 7.02E-06 3.80E-02 1.34E-05 1.23E-04 10 128 "NFIA,SYT4,ZNF384,MED1,RIMS4,PTCH1,SMG7,PTPRE,SRGAP3,ELAVL3" MicroRNA hsa-miR-1197:PITA hsa-miR-1197:PITA_TOP PITA 7.11E-06 3.85E-02 1.36E-05 1.25E-04 12 188 "ADD3,CLSTN1,CCDC88A,LHFPL4,CLASP2,OPCML,TMEM25,DAAM2,MAPK10,TUBB2B,PTPRO,RBM12" MicroRNA hsa-miR-4295:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.37E-06 3.99E-02 1.41E-05 1.29E-04 17 366 "ADARB2,CLIP1,CAPRIN2,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,CEP170,WIPF2,RAB5B,ARHGAP12" MicroRNA "ACTGAAA,MIR-30A-3P:MSigDB" "ACTGAAA,MIR-30A-3P:MSigDB" MSigDB 7.51E-06 4.07E-02 1.43E-05 1.32E-04 12 189 "APC,SLITRK3,MYT1L,CCKBR,FNDC5,ZFYVE9,NEGR1,PRRX1,DSCAM,DBX2,RGS7,SH3GLB1" MicroRNA "ACTGAAA,MIR-30E-3P:MSigDB" "ACTGAAA,MIR-30E-3P:MSigDB" MSigDB 7.51E-06 4.07E-02 1.43E-05 1.32E-04 12 189 "APC,SLITRK3,MYT1L,CCKBR,FNDC5,ZFYVE9,NEGR1,PRRX1,DSCAM,DBX2,RGS7,SH3GLB1" MicroRNA hsa-miR-202:PITA hsa-miR-202:PITA_TOP PITA 7.63E-06 4.13E-02 1.46E-05 1.34E-04 13 222 "KIF1B,CACNA1E,RBFOX2,ARHGAP19,NEGR1,PKN2,ZC3H11A,PTPRD,PTPRO,SNX27,KIF2A,VANGL2,ELAVL3" MicroRNA hsa-miR-548h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-06 4.15E-02 1.46E-05 1.34E-04 15 292 "ARID1A,MDM4,LRRC55,SNCB,MYBPC1,KIF1B,TJP1,KCNK10,NRXN1,NEGR1,SF1,ATRNL1,RBPJ,TOMM20,NAV2" MicroRNA hsa-miR-548bb-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-06 4.15E-02 1.46E-05 1.34E-04 15 292 "ARID1A,MDM4,LRRC55,SNCB,MYBPC1,KIF1B,TJP1,KCNK10,NRXN1,NEGR1,SF1,ATRNL1,RBPJ,TOMM20,NAV2" MicroRNA hsa-miR-548z:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-06 4.15E-02 1.46E-05 1.34E-04 15 292 "ARID1A,MDM4,LRRC55,SNCB,MYBPC1,KIF1B,TJP1,KCNK10,NRXN1,NEGR1,SF1,ATRNL1,RBPJ,TOMM20,NAV2" MicroRNA hsa-miR-4473:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.79E-06 4.22E-02 1.48E-05 1.36E-04 7 56 "CLIP1,CAPRIN2,SPART,TPD52,CEP170,WIPF2,UEVLD" MicroRNA hsa-miR-541:PITA hsa-miR-541:PITA_TOP PITA 7.88E-06 4.26E-02 1.50E-05 1.38E-04 8 78 "SLC1A2,SMARCE1,CADM3,JPH4,SMOC1,TMEM257,CABP1,PRRX1" MicroRNA hsa-miR-548ac:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.97E-06 4.32E-02 1.52E-05 1.39E-04 15 293 "ARID1A,MDM4,LRRC55,SNCB,MYBPC1,KIF1B,TJP1,KCNK10,NRXN1,NEGR1,SF1,ATRNL1,RBPJ,TOMM20,NAV2" MicroRNA hsa-miR-552-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.06E-06 4.36E-02 1.53E-05 1.41E-04 10 130 "EPS8,EML4,SEZ6L,CADM1,CCSER2,CRLS1,VCAN,SYNC,ZYG11B,SH3GLB1" MicroRNA hsa-miR-99b*:mirSVR_highEffct hsa-miR-99b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.06E-06 4.36E-02 1.53E-05 1.41E-04 10 130 "SLC1A7,MYBPC1,TTLL9,ARHGEF7,TCF7L2,FEZ2,PKN2,PRTFDC1,TMEM255A,ZYG11B" MicroRNA hsa-miR-1258:PITA hsa-miR-1258:PITA_TOP PITA 8.06E-06 4.36E-02 1.53E-05 1.41E-04 10 130 "MBP,SLC25A25,ASCL1,DNER,TCF12,PCSK2,RIMS3,WIPF2,PAK5,SLC4A10" MicroRNA "TCCAGAT,MIR-516-5P:MSigDB" "TCCAGAT,MIR-516-5P:MSigDB" MSigDB 8.11E-06 4.39E-02 1.54E-05 1.41E-04 9 103 "ACER3,KCNIP2,MIER1,GNAS,NSD2,SRGAP3,SNX27,RBM12,RASGRP2" MicroRNA hsa-miR-520f-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.11E-06 4.39E-02 1.54E-05 1.41E-04 9 103 "CAPRIN2,SON,CAMK2A,PTGDR2,TPD52,IFFO1,PRKACB,KIAA0513,WIPF2" MicroRNA hsa-miR-136-5p:Functional MTI Functional MTI miRTarbase 8.45E-06 4.57E-02 1.61E-05 1.47E-04 11 160 "ADCYAP1R1,GPR158,MADD,SNAP25,EIF4G3,GANAB,ABCC8,GNAS,RBFOX2,BTF3L4,ABI2" MicroRNA hsa-miR-6893-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.54E-06 4.62E-02 1.62E-05 1.49E-04 24 665 "SDE2,PNMA8B,SFMBT2,SLC2A5,ATM,TMEM151A,B4GALNT1,FAM168A,ZNF638,CAMSAP2,BTRC,GPR26,NRGN,PTBP2,NUCB1,TPM3,TPM4,MFSD4A,FAM131B,KIAA0513,PHYHIP,SNX27,GNE,SYT15" MicroRNA hsa-miR-421:TargetScan hsa-miR-421 TargetScan 8.59E-06 4.65E-02 1.63E-05 1.50E-04 16 332 "EPS8,ABAT,FGF14,ELMOD1,GAS7,ARHGAP5,NCAM1,C11orf87,PRUNE2,FBXL16,PDE4B,ANKS1B,JAKMIP2,OCIAD1,KCNJ10,ABI2" MicroRNA hsa-miR-1262:PITA hsa-miR-1262:PITA_TOP PITA 8.62E-06 4.67E-02 1.64E-05 1.50E-04 10 131 "GNAS,TJP1,RBFOX2,FNDC5,BEST1,SF1,TOX,SYNC,ITGAV,MAGI2" MicroRNA hsa-miR-556-5p:PITA hsa-miR-556-5p:PITA_TOP PITA 8.62E-06 4.67E-02 1.64E-05 1.50E-04 10 131 "ITSN1,ST3GAL3,TCF12,RBFOX2,TUB,MEAF6,TENM4,RIMS4,MAGI2,RNF220" MicroRNA hsa-miR-29c*:mirSVR_highEffct hsa-miR-29c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.78E-06 4.75E-02 1.67E-05 1.53E-04 9 104 "ADGRV1,ERMN,CAPRIN2,USP33,BDNF-AS,OCIAD1,KCNC1,TMEM255A,CAMK1G" MicroRNA hsa-miR-4651:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.81E-06 4.77E-02 1.67E-05 1.53E-04 12 192 "MDM4,PNMA8B,FOXRED2,KIAA1614,NKX2-2,CECR2,TPM3,DLGAP3,UBTF,SPATA6,PACSIN1,MAPK10" MicroRNA hsa-miR-6770-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.81E-06 4.77E-02 1.67E-05 1.53E-04 13 225 "SRARP,SYT9,MRVI1,KCNIP2,FOXRED2,ASTN2,ZFP91,RBFOX2,CADM1,MEAF6,RNF14,ZC3H11A,WIPF2" MicroRNA hsa-miR-4279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.96E-06 4.85E-02 1.70E-05 1.56E-04 20 493 "FAM43B,GRAMD1B,SLC7A14,KIAA1614,DNAH17,TMEM151A,PALLD,CNDP1,GPR26,TNS1,TMPRSS5,NEGR1,RGS6,KIAA0408,PMEPA1,STMN4,RABGAP1L,KCNJ11,WIPF2,PLEKHO1" MicroRNA hsa-miR-1275:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.96E-06 4.85E-02 1.70E-05 1.56E-04 11 161 "ANK1,PKNOX2,NMNAT2,RAP1GAP2,CAMK2A,DLGAP3,UBTF,MEAF6,SPATA6,PTPA,EFNA3" MicroRNA hsa-miR-548d-3p:Functional MTI Functional MTI miRTarbase 9.00E-06 4.87E-02 1.71E-05 1.56E-04 15 296 "ARID1A,MDM4,LRRC55,SNCB,MYBPC1,KIF1B,TJP1,KCNK10,NRXN1,NEGR1,SF1,ATRNL1,RBPJ,TOMM20,NAV2" MicroRNA hsa-miR-940:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.12E-06 4.94E-02 1.73E-05 1.58E-04 25 713 "SDE2,PNMA8B,SFMBT2,SLC2A5,ATM,TMEM151A,B4GALNT1,FAM168A,ZNF638,CAMSAP2,BTRC,GPR26,NRGN,PTBP2,NUCB1,TPM3,TPM4,TUB,MFSD4A,FAM131B,KIAA0513,PHYHIP,SNX27,GNE,SYT15" MicroRNA hsa-miR-6808-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.19E-06 4.98E-02 1.74E-05 1.60E-04 24 668 "SDE2,PNMA8B,SFMBT2,SLC2A5,ATM,TMEM151A,B4GALNT1,FAM168A,ZNF638,CAMSAP2,BTRC,GPR26,NRGN,PTBP2,NUCB1,TPM3,TPM4,MFSD4A,FAM131B,KIAA0513,PHYHIP,SNX27,GNE,SYT15" MicroRNA hsa-miR-1254:PITA hsa-miR-1254:PITA_TOP PITA 9.22E-06 4.99E-02 1.74E-05 1.60E-04 10 132 "CLIP1,ANK1,CAPRIN2,ATP2B2,CADM3,HAP1,MEAF6,FAT3,SF1,PPP3CB" MicroRNA hsa-miR-1273c:mirSVR_highEffct hsa-miR-1273c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.22E-06 4.99E-02 1.74E-05 1.60E-04 10 132 "MEG3,CSMD2,ST3GAL3,SHTN1,UNC5D,CACNB2,CRB1,RBPJ,LRRTM3,OLIG1" MicroRNA hsa-miR-28-5p:Functional MTI Functional MTI miRTarbase 9.49E-06 5.14E-02 1.79E-05 1.65E-04 9 105 "PLEKHG5,TUBB4A,DRAXIN,FAM168A,ZFP91,TPM4,NOS1AP,PRDM2,PIANP" MicroRNA hsa-miR-511-5p:Functional MTI Functional MTI miRTarbase 9.49E-06 5.14E-02 1.79E-05 1.65E-04 9 105 "TTYH1,SESN3,NAXD,KIF1B,KIAA1755,PMEPA1,KCNN3,DPP6,ELAVL3" MicroRNA hsa-miR-4665-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.50E-06 5.15E-02 1.80E-05 1.65E-04 11 162 "ANK1,PKNOX2,NMNAT2,RAP1GAP2,CAMK2A,DLGAP3,UBTF,MEAF6,SPATA6,PTPA,EFNA3" MicroRNA hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA_TOP PITA 9.52E-06 5.15E-02 1.80E-05 1.65E-04 8 80 "SLC1A2,SMARCE1,CADM3,JPH4,SMOC1,TMEM257,CABP1,PRRX1" MicroRNA hsa-miR-451:mirSVR_highEffct hsa-miR-451:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.69E-06 5.25E-02 1.83E-05 1.68E-04 13 227 "MBP,MOBP,SGIP1,SORCS3,CAB39,KIF1B,DCAF5,ADGRL3,POU3F2,RBPJ,CA10,PTPRE,DBX2" MicroRNA hsa-miR-1250:mirSVR_highEffct hsa-miR-1250:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.86E-06 5.34E-02 1.86E-05 1.71E-04 10 133 "GPR158,GPAM,WDTC1,GLS,LGI1,TPD52,MAGI1,JAM2,VCAN,RFX4" MicroRNA hsa-miR-3925-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.86E-06 5.34E-02 1.86E-05 1.71E-04 10 133 "SNAP25,INKA2,TMEM151B,A2ML1,CELF5,TENM4,KIAA1755,PLPP4,FAM131B,TMCC2" MicroRNA hsa-miR-188-5p:TargetScan hsa-miR-188-5p TargetScan 1.01E-05 5.45E-02 1.90E-05 1.74E-04 11 163 "RIMKLA,NRG3,NEK6,KIF1B,NPAS3,GUCY1A2,RBFOX2,MAGI1,LRRTM3,CDH20,NTM" MicroRNA hsa-miR-3614-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-05 5.50E-02 1.91E-05 1.76E-04 13 228 "SERPINA3,SFMBT2,KBTBD12,CECR2,AKNA,GUCY1A2,SCRG1,CCSER2,MICAL2,BDNF-AS,CALN1,GNE,JMJD1C" MicroRNA "ATCATGA,MIR-433:MSigDB" "ATCATGA,MIR-433:MSigDB" MSigDB 1.03E-05 5.55E-02 1.93E-05 1.77E-04 9 106 "KCNIP2,CSMD3,MIER1,PCDH11X,NMT2,HP1BP3,CEP170,STMN4,KCNMA1" MicroRNA hsa-miR-1253:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.58E-02 1.94E-05 1.78E-04 12 195 "SRARP,SYT9,MRVI1,KCNIP2,FOXRED2,ASTN2,CECR2,RBFOX2,RNF14,PTPA,KIAA0513,WIPF2" MicroRNA hsa-miR-518a-3p:mirSVR_highEffct hsa-miR-518a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-05 5.58E-02 1.94E-05 1.78E-04 12 195 "TTYH1,FHL1,TACC2,NSG2,NDUFA5,ARHGEF7,TGFBR3,LGI1,PPP3CB,PRDM2,PARP11,DTNA" MicroRNA hsa-miR-320a:Functional MTI Functional MTI miRTarbase 1.04E-05 5.62E-02 1.95E-05 1.79E-04 22 584 "FOXM1,SORBS1,USP16,AQP4,GART,GNAS,BTRC,PSRC1,NUDT21,TPD52,HMGB1,TUB,VAV2,CHD1L,SF1,RBPJ,NOS1AP,WBP1L,CSDE1,MED24,RTN4,EPB41" MicroRNA hsa-miR-1203:mirSVR_highEffct hsa-miR-1203:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-05 5.65E-02 1.97E-05 1.80E-04 8 81 "SYNDIG1,TOMM40L,STK32C,PAAF1,ADHFE1,TBX15,SPIRE1,YY1AP1" MicroRNA "TCTGGAC,MIR-198:MSigDB" "TCTGGAC,MIR-198:MSigDB" MSigDB 1.04E-05 5.65E-02 1.97E-05 1.80E-04 8 81 "RIMKLA,ARID1A,MSR1,JPH4,SMOC1,NRXN1,SLC25A27,ATG16L1" MicroRNA "GACAATC,MIR-219:MSigDB" "GACAATC,MIR-219:MSigDB" MSigDB 1.05E-05 5.70E-02 1.98E-05 1.82E-04 10 134 "MAPT,EYA1,SOX6,ITSN1,NTNG1,ZCCHC24,NEK6,KIF1B,CAMK2G,DNAJC6" MicroRNA hsa-miR-4530:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.70E-02 1.98E-05 1.82E-04 10 134 "ATAT1,SCN4B,MIER1,SFMBT2,GRID1,ZFP91,LRTM2,NCAN,FAM131B,PTCH1" MicroRNA hsa-miR-487b:mirSVR_lowEffct hsa-miR-487b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-05 5.71E-02 1.98E-05 1.82E-04 15 300 "ADARB2,FABP7,KIF1B,NPAS3,NASP,PCDH11X,ZNF638,CYB561A3,TNS1,ZBED5,FLRT1,NSD2,PPP3CB,MAGI2,PEX5" MicroRNA hsa-miR-1322:PITA hsa-miR-1322:PITA_TOP PITA 1.12E-05 6.09E-02 2.11E-05 1.94E-04 10 135 "TOMM40L,SORBS1,CAMTA1,UNC5D,GPM6A,GRIK2,CDC42,PDE1C,CADM2,HS3ST4" MicroRNA hsa-miR-3942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-05 6.09E-02 2.11E-05 1.94E-04 10 135 "SDE2,SESN3,NBPF1,VXN,NUCB1,OLR1,KIAA1755,BDNF-AS,KCNN3,SH3GLB1" MicroRNA hsa-miR-1238-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-05 6.09E-02 2.11E-05 1.94E-04 10 135 "GRAMD1B,NLGN1,SLC7A14,SLIT1,GRID1,GRIK3,TGFBR3,PTGDR2,SLC22A6,FAM13C" MicroRNA hsa-miR-6887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-05 6.09E-02 2.11E-05 1.94E-04 10 135 "SON,NMNAT2,NFASC,NRGN,NEURL1,RBFOX2,BEST3,DLGAP3,PHYHIP,BDNF-AS" MicroRNA hsa-miR-597:PITA hsa-miR-597:PITA_TOP PITA 1.12E-05 6.09E-02 2.11E-05 1.94E-04 10 135 "GPR158,SLITRK3,MYT1L,B4GALNT1,NCAM1,GANAB,GPM6A,CACNB2,NEGR1,MED1" MicroRNA hsa-miR-545-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.13E-05 6.12E-02 2.12E-05 1.94E-04 11 165 "MDM4,CCDC80,ZFP91,TPM3,NEGR1,ACBD5,VCAN,RBPJ,PLEKHB2,ARHGAP12,EN2" MicroRNA hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 1.13E-05 6.12E-02 2.12E-05 1.94E-04 11 165 "ACER3,SCN4B,GOLGA7B,ITSN1,CADM1,POU3F2,RIMS4,KCND3,FAM135B,RBM12,RPRD1A" MicroRNA hsa-miR-4743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-05 6.46E-02 2.24E-05 2.05E-04 9 108 "ARID1A,FOXG1,MIER1,SFMBT2,SOX1,EMC1,GRIK4,DPP6,TTLL7" MicroRNA hsa-miR-483-3p:PITA hsa-miR-483-3p:PITA_TOP PITA 1.19E-05 6.46E-02 2.24E-05 2.05E-04 9 108 "APBA2,TACC2,YPEL4,RCOR3,WWC1,CAMK2G,UBTF,MED1,CSDE1" MicroRNA hsa-miR-616:PITA hsa-miR-616:PITA_TOP PITA 1.20E-05 6.50E-02 2.25E-05 2.06E-04 10 136 "MYT1L,NFIA,GPM6A,TJP1,FNDC5,MAPK10,FAM131B,CEP170,STMN4,EPB41L2" MicroRNA hsa-miR-6795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-05 6.50E-02 2.25E-05 2.06E-04 10 136 "SON,NMNAT2,NFASC,NRGN,NEURL1,RBFOX2,BEST3,DLGAP3,PHYHIP,BDNF-AS" MicroRNA "AGTCTAG,MIR-151:MSigDB" "AGTCTAG,MIR-151:MSigDB" MSigDB 1.23E-05 6.64E-02 2.30E-05 2.11E-04 5 24 "HPCAL4,NELL1,CAMTA1,BRINP3,NTM" MicroRNA hsa-miR-4428:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-05 6.93E-02 2.39E-05 2.20E-04 10 137 "WAC,MOG,RUFY2,LGI3,TTLL9,FAM168A,TPM3,CADM1,SF1,EN2" MicroRNA hsa-miR-490-3p:PITA hsa-miR-490-3p:PITA_TOP PITA 1.28E-05 6.93E-02 2.39E-05 2.20E-04 10 137 "SCN4B,DOCK10,SHTN1,CAB39,NCAM1,MED1,RBPJ,KCNA1,SMG7,RBM12" MicroRNA hsa-miR-4753-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-05 6.96E-02 2.41E-05 2.21E-04 9 109 "SDE2,ADARB2,WAC,TACC2,TCF7L2,ZFYVE9,VAV2,CEP170,KCNN3" MicroRNA hsa-miR-488-3p:TargetScan hsa-miR-488-3p TargetScan 1.33E-05 7.21E-02 2.49E-05 2.29E-04 15 306 "RIMKLA,CCDC88A,NDUFA5,NFIA,PRUNE2,GUCY1A2,CELF3,REPS2,LGI1,HEPACAM,NLGN3,CADM1,FTO,PLD5,KCNN3" MicroRNA hsa-miR-4524b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-05 7.25E-02 2.50E-05 2.29E-04 13 234 "RTKN,FOXRED2,ALDH4A1,ATP1A2,SPART,ACSL6,P2RX7,SCRG1,NEGR1,VAV2,RNF14,DPYSL5,ZYG11B" MicroRNA hsa-miR-374b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-05 7.25E-02 2.50E-05 2.29E-04 13 234 "ADD3,GPR158,SESN3,CCDC80,SON,MYBPC1,LUZP2,CAMSAP2,SLC25A27,FAT3,PMEPA1,KLRC3,L1CAM" MicroRNA hsa-miR-28-3p:PITA hsa-miR-28-3p:PITA_TOP PITA 1.34E-05 7.25E-02 2.50E-05 2.29E-04 11 168 "CACHD1,SNAP25,ZCCHC24,ZFP91,CDC42,CCSER2,PPP2R5C,CTNND2,MAGI2,GOPC,ARHGAP12" MicroRNA hsa-miR-133b:Functional MTI Functional MTI miRTarbase 1.37E-05 7.41E-02 2.55E-05 2.34E-04 8 84 "EMID1,SESN3,BCL2L2,PTBP2,CDC42,TPM3,PDE1A,NUP214" MicroRNA hsa-miR-203a-3p:Functional MTI Functional MTI miRTarbase 1.44E-05 7.79E-02 2.68E-05 2.46E-04 15 308 "ARID1A,ATM,SON,BCL2L2,GNAS,ZEB1,PAX6,TJP2,PRKACB,MAPK8,KIAA0408,CADM2,KIF2A,SH3GLB1,EN2" MicroRNA hsa-miR-6721-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-05 7.93E-02 2.73E-05 2.51E-04 13 236 "PLEKHG5,WAC,KIAA1614,FXYD6,GJB1,B4GALNT4,CAMK2A,NUMA1,BRSK2,TPD52,TMPRSS5,PACSIN1,DNAJC6" MicroRNA hsa-miR-148a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-05 8.09E-02 2.78E-05 2.55E-04 8 85 "APC2,CCDC80,CACNA1A,TNS1,COL9A2,SH3GLB1,GPR61,RCAN2" MicroRNA hsa-miR-3194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-05 8.09E-02 2.78E-05 2.55E-04 8 85 "APC2,KCNIP2,SFMBT2,AJAP1,NODAL,NEURL1,MEAF6,ATCAY" MicroRNA "AGGCACT,MIR-515-3P:MSigDB" "AGGCACT,MIR-515-3P:MSigDB" MSigDB 1.49E-05 8.09E-02 2.78E-05 2.55E-04 8 85 "HOGA1,YPEL4,JPH4,C11orf87,DPYSL5,LRP8,SLC6A15,EPB41" MicroRNA "ATATGCA,MIR-448:MSigDB" "ATATGCA,MIR-448:MSigDB" MSigDB 1.54E-05 8.35E-02 2.87E-05 2.63E-04 12 203 "ANK2,SH3GL2,NLGN1,KBTBD12,DCAF5,GPM6A,PCDHGA3,GRIK2,PCDH8,PCDH9,PRKAB2,RAVER2" MicroRNA hsa-miR-125a-3p:Functional MTI Functional MTI miRTarbase 1.55E-05 8.40E-02 2.89E-05 2.65E-04 15 310 "WAC,PNMA8B,FYN,GNAS,CACNB2,CECR2,MFSD2A,P2RX7,BTF3L4,ATCAY,FAM131B,DPYSL5,KCNN3,GNE,BSCL2" MicroRNA hsa-miR-383-5p.1:TargetScan hsa-miR-383-5p.1 TargetScan 1.58E-05 8.56E-02 2.94E-05 2.70E-04 11 171 "KIRREL3,NEUROD1,ROBO3,CELF3,PAX6,RBFOX2,FAT3,NXPH1,PLD5,BLOC1S6,PTPRE" MicroRNA hsa-miR-485-5p:Non-Functional MTI (Weak) Non-Functional MTI (Weak) miRTarbase 1.62E-05 8.75E-02 3.01E-05 2.76E-04 21 557 "MDM4,PNMA8B,CDC42BPA,SLC2A5,SLIT1,ATM,WDTC1,RAP1GAP2,ZNF638,AKNA,TPM3,MFSD4A,RIMS4,KIAA0408,PSD,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 1.69E-05 9.14E-02 3.14E-05 2.88E-04 18 431 "ACLY,PLEKHG5,APC,TACC2,DKK3,EMC1,BCL2L2,GANAB,TMEM136,NRDC,TMEM9,HNRNPK,NEGR1,PIK3CD,MED1,RIMS4,CEP170,C1orf109" MicroRNA hsa-miR-3124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-05 9.20E-02 3.16E-05 2.90E-04 12 205 "CDHR1,MRVI1,SLC25A25,CDC42BPA,GAS7,SMOC1,TMEM136,GRID1,ZFP91,PTGDR2,TOMM20,RAVER2" MicroRNA hsa-miR-3928-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-05 9.30E-02 3.19E-05 2.93E-04 7 63 "SYT9,RUFY2,NSG2,RBFOX2,TLX1,MEAF6,SH3GLB1" MicroRNA hsa-miR-6806-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-05 9.30E-02 3.19E-05 2.93E-04 7 63 "SYT9,RUFY2,NSG2,RBFOX2,TLX1,MEAF6,SH3GLB1" MicroRNA hsa-miR-6858-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-05 9.47E-02 3.25E-05 2.98E-04 10 142 "APC2,KCNIP2,API5,NODAL,AKNA,NEURL1,RBFOX2,FAT3,WIPF2,UEVLD" MicroRNA hsa-miR-362-5p:TargetScan hsa-miR-362-5p TargetScan 1.75E-05 9.47E-02 3.25E-05 2.98E-04 10 142 "MRVI1,ADCYAP1R1,ADHFE1,MED1,RIMS4,PROX1,PTPRD,KCNN3,KIF2A,ABI2" MicroRNA hsa-miR-99b:mirSVR_lowEffct hsa-miR-99b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-05 9.54E-02 3.27E-05 3.00E-04 11 173 "MOG,SLC8A2,SLC14A1,BEST3,DOCK7,PRKCZ,EDRF1,PLPPR4,KCNJ11,TTLL7,EPB41L1" MicroRNA hsa-miR-640:PITA hsa-miR-640:PITA_TOP PITA 1.76E-05 9.54E-02 3.27E-05 3.00E-04 11 173 "SH3GL2,SOX5,NELL1,CAMTA1,WSCD1,GRIK2,ZFP91,TPM3,PRRX1,PKN2,CDH20" MicroRNA hsa-miR-450a-1-3p:Functional MTI Functional MTI miRTarbase 1.78E-05 9.65E-02 3.31E-05 3.03E-04 17 392 "MDM4,SOX6,CCDC80,CLSTN1,SLC1A2,SLC6A9,DNAH17,GNG4,GRIK2,ZFP91,FTO,FAT3,PRKAB2,DNAH9,RAB5B,GPR61,ABI2" MicroRNA hsa-miR-214-3p:Functional MTI Functional MTI miRTarbase 1.78E-05 9.66E-02 3.31E-05 3.03E-04 12 206 "SCN4B,SFMBT2,DKK3,KIF1B,BCL2L2,TPM3,LRTM2,CADM1,VAV2,NCAN,MAPK8,RAB5B" MicroRNA hsa-miR-572:mirSVR_lowEffct hsa-miR-572:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-05 9.89E-02 3.39E-05 3.11E-04 16 353 "MAPT,EXTL1,ATAT1,CNIH2,ZCCHC17,SLC8A3,NSG2,WDTC1,BCL2L2,VAMP1,CHGA,NSD2,PRKCG,PHYHIP,PRDM2,OLIG1" MicroRNA hsa-miR-3924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-05 9.89E-02 3.39E-05 3.11E-04 13 241 "MDM4,FYN,SOX5,NFIA,OPCML,DOCK7,PROX1,KIAA0408,PTPRD,KCNK1,RAB5B,L1CAM,ABI2" MicroRNA hsa-miR-513a-5p:Functional MTI Functional MTI miRTarbase 1.87E-05 1.01E-01 3.47E-05 3.18E-04 12 207 "SLC25A25,TOMM40L,GPAM,NUDT21,OLR1,TGFBR3,ZNF384,PNKD,RGS6,CTNND1,BDNF-AS,EN2" MicroRNA hsa-miR-301a-3p:Functional MTI Functional MTI miRTarbase 1.96E-05 1.06E-01 3.63E-05 3.33E-04 17 395 "ADARB2,CLIP1,CAPRIN2,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,CEP170,WIPF2,RAB5B,ARHGAP12" MicroRNA hsa-miR-125b:mirSVR_highEffct hsa-miR-125b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.97E-05 1.06E-01 3.64E-05 3.34E-04 18 436 "CNIH2,BCAN,SHTN1,CGREF1,ASPH,ATM,USP2,AIFM1,SULT4A1,MICAL2,MASP1,STMN4,RABGAP1L,KCNMA1,KLRC2,RASGRF1,SEC61A2,SLC4A10" MicroRNA hsa-miR-361-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-05 1.07E-01 3.65E-05 3.35E-04 10 144 "APC2,NPAS3,BCL2L2,SMOC1,CADM1,VCAN,ZBTB16,ATN1,FAM135B,VANGL2" MicroRNA hsa-miR-663a:Functional MTI Functional MTI miRTarbase 1.98E-05 1.07E-01 3.65E-05 3.35E-04 10 144 "DPF1,PDZD4,APC,SLC1A2,NRGN,PIK3CD,PACSIN1,MICAL2,NAV2,EEF1A2" MicroRNA hsa-miR-6788-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-05 1.07E-01 3.65E-05 3.35E-04 20 521 "SOX6,CLSTN1,SLC1A2,DNAH17,AJAP1,GNG4,CHRNB2,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,PTPRE,SNX27,DNAH9,RAB5B,PLEKHB2,ABI2" MicroRNA hsa-miR-493-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-05 1.07E-01 3.66E-05 3.36E-04 9 115 "WAC,USP28,RPH3A,ARHGAP5,SYT4,GRIK3,OLR1,USP2,L1CAM" MicroRNA hsa-miR-4762-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-05 1.07E-01 3.66E-05 3.36E-04 9 115 "KIF1B,NUCB1,FAM181B,NSD2,OSBPL3,KIAA0513,L1CAM,SH3GLB1,ARHGAP12" MicroRNA hsa-miR-454-3p:Functional MTI Functional MTI miRTarbase 2.03E-05 1.10E-01 3.74E-05 3.43E-04 17 396 "ADARB2,CLIP1,CAPRIN2,SALL3,SPART,SMOC1,ERBIN,CAMSAP2,PRUNE2,TCF7L2,ZFYVE9,BTF3L4,ACBD5,CEP170,WIPF2,RAB5B,ARHGAP12" MicroRNA hsa-miR-1251:PITA hsa-miR-1251:PITA_TOP PITA 2.09E-05 1.13E-01 3.87E-05 3.55E-04 8 89 "SDE2,GPR158,VXN,CELF3,TMEM257,TPD52,TPM3,CTNND1" MicroRNA hsa-miR-548ah-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-05 1.17E-01 4.00E-05 3.67E-04 15 319 "MDM4,ADAR,F3,RUFY2,CAPRIN2,LUZP2,KCNK10,TPM4,PFKFB3,ZFYVE9,BTF3L4,RBPJ,KIAA0513,RAB5B,SH3GLB1" MicroRNA hsa-miR-31*:mirSVR_highEffct hsa-miR-31*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-05 1.21E-01 4.14E-05 3.79E-04 16 359 "ERICH3,ITSN1,SH3GL2,SYBU,MSR1,NSG2,RND1,GPR88,CRB1,BEST3,CHRM1,CADM1,RAB39A,MASP1,WIPF2,RGS7" MicroRNA hsa-miR-3609:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-05 1.22E-01 4.14E-05 3.80E-04 15 320 "MDM4,ADAR,F3,RUFY2,CAPRIN2,LUZP2,KCNK10,TPM4,PFKFB3,ZFYVE9,BTF3L4,RBPJ,KIAA0513,RAB5B,SH3GLB1" MicroRNA hsa-miR-184:PITA hsa-miR-184:PITA_TOP PITA 2.26E-05 1.22E-01 4.16E-05 3.82E-04 5 27 "NTNG1,ADGRB2,SF1,SMG7,SIDT2" MicroRNA "GTTATAT,MIR-410:MSigDB" "GTTATAT,MIR-410:MSigDB" MSigDB 2.27E-05 1.23E-01 4.19E-05 3.84E-04 8 90 "ATP2B2,SOX1,C11orf87,GRIA2,PCDH8,HMGB1,TMEFF2,ATG16L1" MicroRNA hsa-miR-449b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-05 1.23E-01 4.19E-05 3.84E-04 9 117 "LGR4,ADAR,BCL2L2,INKA2,TMEM151B,MFSD2A,RBFOX2,OSBPL3,PTCH1" MicroRNA hsa-miR-6877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-05 1.23E-01 4.19E-05 3.84E-04 9 117 "FGF1,SNAP25,DKK3,ERBIN,VAMP1,TMEM151B,NEGR1,ABI2,CBLN2" MicroRNA hsa-miR-135b*:mirSVR_highEffct hsa-miR-135b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-05 1.24E-01 4.20E-05 3.86E-04 18 441 "SYT9,ERMN,ANK2,ZNF365,CCDC88A,NMNAT2,OS9,CAMTA1,CNTN2,DDR2,USP2,INA,FADS2,CNRIP1,BDNF-AS,PLPPR4,PARP11,ARHGAP12" MicroRNA hsa-miR-3152-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.34E-05 1.27E-01 4.31E-05 3.95E-04 7 66 "SESN3,ASTN2,DDR2,CD81,HMGB1,MAPK10,KCNN3" MicroRNA hsa-miR-128-3p:Functional MTI Functional MTI miRTarbase 2.39E-05 1.29E-01 4.39E-05 4.03E-04 20 528 "SDE2,TOMM40L,GAS7,GPAM,ARHGAP5,ALDH4A1,FYN,WDTC1,RND1,TGFBR3,INA,PDE3B,TUB,PNKD,RGS6,ZYG11B,RET,ARHGAP12,EN2,EPB41L1" MicroRNA hsa-miR-521:mirSVR_highEffct hsa-miR-521:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-05 1.31E-01 4.45E-05 4.08E-04 11 179 "PDE8B,SORCS3,CLASP2,NELL1,PCDH11X,TCF7L2,GRIA4,GRIK2,NOS1AP,KCNMA1,RGR" MicroRNA "AAAGGAT,MIR-501:MSigDB" "AAAGGAT,MIR-501:MSigDB" MSigDB 2.43E-05 1.32E-01 4.48E-05 4.11E-04 9 118 "SCN3A,CACHD1,NFASC,RGL1,CAMTA1,HES5,SYNC,RET,ELAVL4" MicroRNA hsa-miR-668:mirSVR_highEffct hsa-miR-668:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-05 1.35E-01 4.59E-05 4.21E-04 18 444 "KLHL32,API5,LRRC55,ASPH,CLASP2,NELL1,ZEB1,PCDH9,NEGR1,PRRX1,IFFO1,POU3F2,DZIP3,KCNK2,DPP6,FGFBP3,RAVER2,SLC4A10" MicroRNA "CAGCAGG,MIR-370:MSigDB" "CAGCAGG,MIR-370:MSigDB" MSigDB 2.50E-05 1.36E-01 4.60E-05 4.22E-04 10 148 "ANK3,ST3GAL3,AQP4,PKNOX2,GABBR1,NFASC,NCDN,TPM4,IFFO1,DSCAM" MicroRNA hsa-miR-662:mirSVR_highEffct hsa-miR-662:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.50E-05 1.36E-01 4.60E-05 4.22E-04 10 148 "ADORA1,ITSN1,NTNG1,TBX15,GRIK4,LINC00839,MAEL,PRMT8,TLX1,PARD6A" MicroRNA hsa-miR-518e:mirSVR_lowEffct hsa-miR-518e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-05 1.37E-01 4.64E-05 4.26E-04 17 403 "FOXRED2,LRRC7,MOBP,PPFIA1,ZNF365,ZNF638,BTRC,CACNB2,AKNA,MAEL,CASC2,TLX1,NRXN1,CCSER2,P2RY12,DNM2,PARP11" MicroRNA "GTGTGAG,MIR-342:MSigDB" "GTGTGAG,MIR-342:MSigDB" MSigDB 2.58E-05 1.40E-01 4.74E-05 4.35E-04 7 67 "SOX6,SEPT3,GRIN1,NSD2,CTNND1,KLK6,PLPPR4" MicroRNA hsa-miR-30c-1-3p:Functional MTI Functional MTI miRTarbase 2.58E-05 1.40E-01 4.74E-05 4.35E-04 20 531 "SOX6,CLSTN1,SLC1A2,DNAH17,AJAP1,GNG4,CHRNB2,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,PTPRE,SNX27,DNAH9,RAB5B,PLEKHB2,ABI2" MicroRNA hsa-miR-4796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.60E-05 1.41E-01 4.77E-05 4.37E-04 14 286 "MAPT,ADAR,F3,RUFY2,CAPRIN2,LUZP2,PRUNE2,TPM4,ZFYVE9,BTF3L4,CTNND1,KIAA0513,RAB5B,SH3GLB1" MicroRNA hsa-miR-6819-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.60E-05 1.41E-01 4.77E-05 4.38E-04 9 119 "FGF1,SNAP25,DKK3,ERBIN,VAMP1,TMEM151B,NEGR1,ABI2,CBLN2" MicroRNA hsa-miR-6887-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-05 1.45E-01 4.91E-05 4.51E-04 11 181 "ACTN2,PNMA8B,SMARCE1,DKK3,INKA2,TMEM151B,PADI2,TNS1,PNKD,KCNJ10,EPB41L1" MicroRNA hsa-miR-410-3p:Functional MTI Functional MTI miRTarbase 2.68E-05 1.45E-01 4.91E-05 4.51E-04 13 250 "ACER3,KIAA1109,CCDC80,MIER1,MYBPC1,AJAP1,GRID1,TPD52,MEAF6,SLC25A27,PMEPA1,CADM2,CSDE1" MicroRNA hsa-miR-127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-05 1.51E-01 5.10E-05 4.68E-04 9 120 "MBP,SYT9,ARID1A,DGKD,RUFY2,NSG2,PCDH9,MEAF6,SH3GLB1" MicroRNA hsa-miR-6748-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-05 1.51E-01 5.10E-05 4.68E-04 9 120 "CLIP1,SOX5,DIRAS1,NUCB1,SLC22A6,UBTF,NAV2,RAB5B,ABI2" MicroRNA hsa-miR-6859-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-05 1.53E-01 5.16E-05 4.74E-04 11 182 "PRR5L,CCDC80,SFMBT2,SON,CECR2,DDR2,ZFP91,BTF3L4,WIPF2,DNM2,C12orf4" MicroRNA hsa-miR-409-5p:PITA hsa-miR-409-5p:PITA_TOP PITA 2.89E-05 1.56E-01 5.28E-05 4.85E-04 8 93 "ARHGAP5,PHYHIPL,GPM6A,PUM1,DNAJC6,LRP8,KCNA1,KCNK1" MicroRNA hsa-miR-585:mirSVR_lowEffct hsa-miR-585:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.96E-05 1.61E-01 5.42E-05 4.98E-04 11 183 "CEND1,FAM43B,SORCS1,HOGA1,NSG2,KLHL4,PPP2R5C,KCNJ9,KCNJ10,RTN4,PHC2" MicroRNA hsa-miR-3125:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.96E-05 1.61E-01 5.42E-05 4.98E-04 11 183 "PRR5L,CCDC80,SFMBT2,SON,CECR2,DDR2,ZFP91,BTF3L4,WIPF2,DNM2,C12orf4" MicroRNA hsa-miR-1180:mirSVR_highEffct hsa-miR-1180:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.97E-05 1.61E-01 5.44E-05 4.99E-04 10 151 "LRRC7,HPCAL4,DACH2,TTLL9,ARHGEF7,PCDH9,SEZ6L,PDE3B,CNIH3,PRDM2" MicroRNA hsa-miR-544a:Functional MTI Functional MTI miRTarbase 2.97E-05 1.61E-01 5.44E-05 4.99E-04 10 151 "SLC7A14,SMARCE1,NEUROD1,ASTN2,GOLGB1,FBXL16,ADGRG1,DUSP26,SF1,EPB41" MicroRNA hsa-miR-30d-5p:Functional MTI Functional MTI miRTarbase 3.02E-05 1.64E-01 5.52E-05 5.06E-04 16 368 "CDC7,CHST15,SEMA6A,FOXG1,MTR,ATM,AZIN2,EML4,ZMYND8,PPP3CB,MAPK8,EDRF1,COPS7A,SEC61A2,RNF220,EPB41" MicroRNA "TGTGTGA,MIR-377:MSigDB" "TGTGTGA,MIR-377:MSigDB" MSigDB 3.12E-05 1.69E-01 5.69E-05 5.22E-04 11 184 "ARID1A,MIER1,MADD,NKX2-2,CAMTA1,NEGR1,NSD2,PUM1,DNAJC6,KCNMA1,RET" MicroRNA hsa-miR-3913-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-05 1.69E-01 5.70E-05 5.23E-04 16 369 "MDM4,SOX6,CCDC80,CLSTN1,SLC1A2,SLC6A9,DNAH17,GNG4,GRIK2,ZFP91,FTO,FAT3,SYNC,DNAH9,RAB5B,ABI2" MicroRNA hsa-miR-212-3p:Functional MTI Functional MTI miRTarbase 3.12E-05 1.69E-01 5.70E-05 5.23E-04 8 94 "DPF1,ACHE,EML4,TJP1,PTCH1,RAB5B,CALN1,PARP11" MicroRNA hsa-miR-520f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-05 1.70E-01 5.72E-05 5.25E-04 7 69 "SMARCE1,DKK3,DDR2,SPATA6,PLEKHB2,ZYG11B,NUP214" MicroRNA hsa-miR-512-5p:PITA hsa-miR-512-5p:PITA_TOP PITA 3.15E-05 1.70E-01 5.74E-05 5.27E-04 10 152 "BCL2L2,SYT4,GRIN1,GRM3,CHRM1,KCNA6,SMG7,WIPF2,DBX2,ABI2" MicroRNA hsa-miR-4695-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-05 1.74E-01 5.87E-05 5.39E-04 16 370 "MRVI1,SLC30A10,MAGI3,SLC2A5,SLIT1,ATM,FAM168A,ACSBG1,GNG4,BTRC,DDR1,NUCB1,TPM3,FTO,KIAA0513,BSDC1" MicroRNA hsa-miR-3122:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-05 1.74E-01 5.87E-05 5.39E-04 16 370 "MDM4,SOX6,CCDC80,CLSTN1,SLC1A2,SLC6A9,DNAH17,GNG4,GRIK2,ZFP91,FTO,FAT3,SYNC,DNAH9,RAB5B,ABI2" MicroRNA hsa-miR-1249:PITA hsa-miR-1249:PITA_TOP PITA 3.36E-05 1.82E-01 6.11E-05 5.61E-04 4 15 "VAMP1,HNRNPK,NRXN2,POU3F2" MicroRNA hsa-miR-215:PITA hsa-miR-215:PITA_TOP PITA 3.37E-05 1.82E-01 6.14E-05 5.63E-04 8 95 "SDE2,CSMD3,SCN3A,PKP4,ADGRL3,PCDH9,ARHGAP19,CADM1" MicroRNA hsa-miR-192:PITA hsa-miR-192:PITA_TOP PITA 3.37E-05 1.82E-01 6.14E-05 5.63E-04 8 95 "SDE2,CSMD3,SCN3A,PKP4,ADGRL3,PCDH9,ARHGAP19,CADM1" MicroRNA hsa-miR-532-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-05 1.84E-01 6.20E-05 5.69E-04 12 220 "TUBB4A,SCMH1,ZCCHC24,GNAS,CACNA1A,ACSL6,CAMK2G,FGFR1OP2,DPYSL5,PTAFR,ABI2,ELAVL3" MicroRNA hsa-miR-4487:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-05 1.84E-01 6.20E-05 5.69E-04 12 220 "GAS7,SMARCE1,IGSF9B,LHFPL4,NFASC,ACSBG1,CYB561A3,TMEM9,FAT3,HP1BP3,ST8SIA3,PIANP" MicroRNA hsa-miR-516a-5p:mirSVR_highEffct hsa-miR-516a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.44E-05 1.86E-01 6.26E-05 5.74E-04 11 186 "STK32C,SNCB,MYBPC1,SALL3,KIF1B,GRIA2,SEZ6L,PRMT8,VCAN,PTPRE,OLIG1" MicroRNA hsa-miR-4504:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-05 1.86E-01 6.26E-05 5.74E-04 7 70 "FOXRED2,FOXG1,GFRA1,KIAA0408,PRDM2,CSDE1,RABGAP1L" MicroRNA hsa-miR-4710:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-05 1.91E-01 6.40E-05 5.87E-04 10 154 "PNMA8B,SCN4B,EMC1,AJAP1,ACSBG1,SF1,NOS1AP,WIPF2,DNAH9,EN2" MicroRNA hsa-miR-759:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-05 1.96E-01 6.57E-05 6.03E-04 11 187 "RABEPK,FOXRED2,MAGI3,SLC8A3,CAPRIN2,EMC1,VXN,OLR1,COL9A2,DOCK7,KCNN3" MicroRNA hsa-miR-30c-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-05 1.96E-01 6.58E-05 6.03E-04 20 544 "SOX6,CLSTN1,SLC1A2,DNAH17,AJAP1,GNG4,CHRNB2,FTO,BTF3L4,FAT3,MFSD4A,DOCK7,CTNND1,DPYSL5,PTPRE,SNX27,DNAH9,RAB5B,PLEKHB2,ABI2" MicroRNA hsa-miR-30b-5p:Functional MTI Functional MTI miRTarbase 3.76E-05 2.03E-01 6.82E-05 6.26E-04 17 416 "ACER3,CDC7,CHST15,SEMA6A,FOXG1,MTR,ATM,EML4,ZMYND8,CAMKV,PPP3CB,MAPK8,LRP8,BLOC1S6,SEC61A2,RNF220,EPB41" MicroRNA hsa-miR-6823-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.78E-05 2.05E-01 6.86E-05 6.29E-04 7 71 "FABP7,ASIC4,PKNOX2,NEGR1,PLD5,TMCC2,FAM135B" MicroRNA hsa-miR-668-3p:TargetScan hsa-miR-668-3p TargetScan 3.84E-05 2.08E-01 6.97E-05 6.40E-04 9 125 "MAPT,ACSBG1,MMD2,CAMK2G,PAX6,PDE3B,NEGR1,PRRX1,MED1" MicroRNA hsa-miR-2277:mirSVR_highEffct hsa-miR-2277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.84E-05 2.08E-01 6.97E-05 6.40E-04 9 125 "ANK2,ARFGAP2,BRSK2,GUCY1A2,PPP3CB,NRSN1,EDRF1,SMG7,DPP6" MicroRNA hsa-miR-151-5p:PITA hsa-miR-151-5p:PITA_TOP PITA 3.86E-05 2.09E-01 6.99E-05 6.41E-04 5 30 "IGSF9B,SNAP25,NMNAT2,RIMS4,ELAVL3" MicroRNA hsa-miR-487b:PITA hsa-miR-487b:PITA_TOP PITA 3.86E-05 2.09E-01 6.99E-05 6.41E-04 5 30 "SDE2,CLIP1,ITSN1,GRM3,PAK5" MicroRNA hsa-miR-6728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.92E-05 2.12E-01 7.10E-05 6.51E-04 8 97 "FGF1,SNAP25,RFFL,GRIK3,PAX6,KIAA0408,ELAVL3,UEVLD" MicroRNA hsa-miR-384:PITA hsa-miR-384:PITA_TOP PITA 3.93E-05 2.13E-01 7.12E-05 6.53E-04 10 156 "CLIP1,NCAM1,ERBIN,CAMK2G,CADM1,RIMS4,SRGAP3,SNX27,ST8SIA3,RCAN2" MicroRNA hsa-miR-3190-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.93E-05 2.13E-01 7.12E-05 6.53E-04 10 156 "ARID1A,ADCY2,WAC,ALDH4A1,PACSIN1,ACBD5,PPP2R5C,FAM131B,KCNJ10,SSPN" MicroRNA hsa-miR-517b:PITA hsa-miR-517b:PITA_TOP PITA 3.96E-05 2.14E-01 7.16E-05 6.57E-04 6 49 "TBX15,ATF7,CAMK2G,NRXN1,LRRTM3,OLFM3" MicroRNA "GGGATGC,MIR-324-5P:MSigDB" "GGGATGC,MIR-324-5P:MSigDB" MSigDB 3.96E-05 2.14E-01 7.16E-05 6.57E-04 6 49 "ARID1A,SEPT3,ZFP91,CAMKV,NSD2,PRKCG" MicroRNA hsa-miR-548n:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-05 2.18E-01 7.27E-05 6.67E-04 13 260 "CLIP1,SOX6,LRRC55,SON,SALL3,KIF1B,SMOC1,CAMSAP2,GPR26,PTBP2,RBFOX2,PAK5,JMJD1C" MicroRNA hsa-miR-1282:mirSVR_highEffct hsa-miR-1282:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-05 2.25E-01 7.50E-05 6.88E-04 10 157 "EYA1,FGF14,SLC2A5,MSRA,MYBPC1,ARHGEF7,ASTN2,FMN2,ZNF385B,RCAN2" MicroRNA hsa-miR-590-5p:PITA hsa-miR-590-5p:PITA_TOP PITA 4.18E-05 2.26E-01 7.56E-05 6.94E-04 13 261 "SLC30A10,SOX6,SLC8A3,SOX5,PHLDB1,CAMTA1,HNRNPK,CADM1,TENM4,RBPJ,MAPK10,KCNA1,DLG2" MicroRNA hsa-miR-4801:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-05 2.28E-01 7.62E-05 6.99E-04 8 98 "ADCYAP1R1,NDUFA5,AJAP1,OLR1,TJP1,ACBD5,KIAA0513,SFXN5" MicroRNA hsa-miR-4664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-05 2.28E-01 7.62E-05 6.99E-04 8 98 "MDM4,FOXRED2,NMNAT2,UBTF,SPATA6,MICAL2,MAPK10,VANGL2" MicroRNA hsa-miR-6843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-05 2.29E-01 7.65E-05 7.02E-04 12 225 "RCSD1,NLGN4X,KIF1B,ERBIN,NUCB1,GRID1,TPM3,PCSK2,ATCAY,FGFR1OP2,BLOC1S6,RABGAP1L" MicroRNA hsa-miR-6848-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-05 2.29E-01 7.65E-05 7.02E-04 12 225 "RCSD1,NLGN4X,KIF1B,ERBIN,NUCB1,GRID1,TPM3,PCSK2,ATCAY,FGFR1OP2,BLOC1S6,RABGAP1L" MicroRNA hsa-miR-6851-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.34E-05 2.35E-01 7.84E-05 7.19E-04 15 339 "ANK1,SLC2A5,ASPH,FXYD6,DDR1,PTBP2,FAT3,ACBD5,NOS1AP,KIAA0513,SIRPA,HP1BP3,PLEKHB2,PARP11,SSPN" MicroRNA hsa-miR-548f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.35E-05 2.35E-01 7.85E-05 7.20E-04 13 262 "ADARB2,CCDC80,LRRC55,SPART,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-4689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.35E-05 2.36E-01 7.86E-05 7.21E-04 9 127 "MRVI1,WDTC1,NMNAT2,TNS1,SF1,C1orf109,WIPF2,BSCL2,EN2" MicroRNA hsa-miR-1273g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-05 2.36E-01 7.86E-05 7.21E-04 19 507 "ATAT1,PNMA8B,GRAMD1B,MAGI3,CCDC80,EMC1,CAMK2G,TMEM151B,RFFL,MFSD2A,COL9A2,PPP3CB,DOCK7,PLPP4,NOS1AP,HP1BP3,OCIAD1,KCNN3,EPB41" MicroRNA hsa-miR-527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-05 2.37E-01 7.89E-05 7.24E-04 10 158 "MAPT,FOXRED2,GAS7,CCDC80,UNC5D,PRUNE2,FAM69C,CRLS1,KIAA0513,RAVER2" MicroRNA hsa-miR-501-5p:Functional MTI Functional MTI miRTarbase 4.38E-05 2.37E-01 7.89E-05 7.24E-04 10 158 "SLC25A25,SLC1A2,MYT1L,C11orf87,OS9,GPM6B,RGS6,NTM,KCNN3,VANGL2" MicroRNA hsa-miR-6775-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.45E-05 2.41E-01 8.01E-05 7.35E-04 6 50 "INKA2,GANAB,PFKFB3,CHRNB2,VANGL2,VWA5A" MicroRNA hsa-miR-548aj-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.45E-01 8.14E-05 7.46E-04 13 263 "ADARB2,CCDC80,LRRC55,SPART,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-548g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.45E-01 8.14E-05 7.46E-04 13 263 "ADARB2,CCDC80,LRRC55,SPART,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-21:PITA hsa-miR-21:PITA_TOP PITA 4.52E-05 2.45E-01 8.14E-05 7.46E-04 13 263 "SLC30A10,SOX6,SLC8A3,SOX5,PHLDB1,CAMTA1,HNRNPK,CADM1,TENM4,RBPJ,MAPK10,KCNA1,DLG2" MicroRNA hsa-miR-548x-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.45E-01 8.14E-05 7.46E-04 13 263 "ADARB2,CCDC80,LRRC55,SPART,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-4731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.54E-05 2.46E-01 8.16E-05 7.48E-04 8 99 "ADCYAP1R1,NDUFA5,AJAP1,OLR1,TJP1,ACBD5,KIAA0513,SFXN5" MicroRNA hsa-miR-1238:PITA hsa-miR-1238:PITA_TOP PITA 4.55E-05 2.46E-01 8.18E-05 7.50E-04 5 31 "SLITRK1,API5,ATP2B2,CELF3,JAKMIP2" MicroRNA hsa-miR-744-5p:TargetScan hsa-miR-744-5p TargetScan 4.55E-05 2.46E-01 8.18E-05 7.50E-04 5 31 "CSMD2,PLEKHG5,NRGN,HPSE2,FAM57B" MicroRNA hsa-miR-4257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-05 2.47E-01 8.20E-05 7.52E-04 16 381 "PLEKHG5,TUBB4A,MAGI3,CCDC80,SLC8A3,TMEM151A,SCN3B,ACSBG1,GNG4,DDR1,DIRAS1,NUCB1,TPM3,SCRG1,KCNH1,ST8SIA3" MicroRNA "CTTGTAT,MIR-381:MSigDB" "CTTGTAT,MIR-381:MSigDB" MSigDB 4.60E-05 2.49E-01 8.26E-05 7.58E-04 11 192 "SHANK2,EIF4G3,ARPP21,KIF1B,GFRA1,NFIA,ANO4,NRXN1,OSBPL3,EPB41,EPB41L1" MicroRNA hsa-miR-1226-3p:Functional MTI Functional MTI miRTarbase 4.62E-05 2.50E-01 8.29E-05 7.60E-04 12 227 "RBM10,CNTNAP3,ADAR,TUBB4A,NDUFA5,GPR26,GRIK3,TMEM25,ELMO1,CSDE1,ZNF248,EPB41L1" MicroRNA hsa-miR-4321:mirSVR_lowEffct hsa-miR-4321:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.62E-05 2.50E-01 8.29E-05 7.60E-04 12 227 "ASRGL1,PPFIA1,BCAN,CLSTN1,USP33,KAZN,CACNA1E,PCDHGA3,PRKACB,HS3ST4,SLC25A48,RFX4" MicroRNA hsa-miR-1234:mirSVR_lowEffct hsa-miR-1234:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.62E-05 2.50E-01 8.29E-05 7.60E-04 17 423 "PAQR6,MEG3,PPFIA1,SH3GL2,SCMH1,MTR,TNIK,SEMA4A,GPR17,CCKBR,MAEL,PTGDR2,CHGA,PLXNB3,NKAIN4,SIRPA,KCNK1" MicroRNA hsa-miR-193a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.63E-05 2.51E-01 8.30E-05 7.62E-04 9 128 "RTKN,TCF7L2,TNFRSF1B,ZNF384,HMGB1,PPP2R5C,MAPK8,RGMA,ABI2" MicroRNA hsa-miR-95:mirSVR_highEffct hsa-miR-95:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.63E-05 2.51E-01 8.30E-05 7.62E-04 9 128 "ADGRV1,DOCK10,INKA2,CACNA1E,GPR88,TPM3,RGS6,PRKACB,ZYG11B" MicroRNA hsa-miR-4451:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-05 2.51E-01 8.30E-05 7.62E-04 9 128 "EPS8,MDM4,TPD52,TPM3,BTF3L4,CSDE1,DNAH9,C12orf4,ZYG11B" MicroRNA hsa-miR-5096:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.69E-05 2.54E-01 8.41E-05 7.72E-04 14 302 "SERPINA3,ADCYAP1R1,API5,CADPS,ATP1A2,ZCCHC24,KIF1B,ZNF384,MEAF6,POU3F2,JAKMIP2,GNE,ZYG11B,UEVLD" MicroRNA hsa-miR-196a-5p:Functional MTI Functional MTI miRTarbase 4.86E-05 2.63E-01 8.71E-05 8.00E-04 14 303 "SYT9,LGR4,ANXA7,RUFY2,PALLD,SALL3,PRUNE2,GRIK4,TGFBR3,NRXN1,ITGAV,ATG16L1,C12orf4,RFX5" MicroRNA hsa-miR-361-5p:Functional MTI Functional MTI miRTarbase 4.87E-05 2.64E-01 8.72E-05 8.00E-04 10 160 "ACLY,MDM4,SON,LHFPL4,VXN,KIAA1549L,FGFR1OP2,COPS7A,WIPF2,ABI2" MicroRNA hsa-miR-937:mirSVR_lowEffct hsa-miR-937:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.87E-05 2.64E-01 8.72E-05 8.00E-04 10 160 "TOMM40L,SLC30A10,SEMA6C,MT3,ARFGAP1,SNCB,KAZN,GRIA1,POU3F4,CRMP1" MicroRNA hsa-miR-635:PITA hsa-miR-635:PITA_TOP PITA 4.87E-05 2.64E-01 8.72E-05 8.00E-04 8 100 "RTN1,FOXG1,DCAF5,VAMP1,ATF7,FAM131B,PROX1,DLG2" MicroRNA hsa-miR-4281:mirSVR_highEffct hsa-miR-4281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.87E-05 2.64E-01 8.72E-05 8.00E-04 8 100 "PKP4,PAAF1,PRMT8,BEST3,HERC2P3,MASP1,ABCC9,RFX4" MicroRNA "ATGTAGC,MIR-221:MSigDB" "ATGTAGC,MIR-221:MSigDB" MSigDB 4.92E-05 2.66E-01 8.80E-05 8.07E-04 9 129 "ARID1A,SYBU,SHTN1,SHANK2,SNCB,TCF12,MAPK10,TOX,RIMS3" MicroRNA "ATGTAGC,MIR-222:MSigDB" "ATGTAGC,MIR-222:MSigDB" MSigDB 4.92E-05 2.66E-01 8.80E-05 8.07E-04 9 129 "ARID1A,SYBU,SHTN1,SHANK2,SNCB,TCF12,MAPK10,TOX,RIMS3" MicroRNA hsa-miR-6759-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.98E-05 2.70E-01 8.91E-05 8.17E-04 6 51 "ATM,KLHL4,DDR2,PFKFB3,PNKD,RABGAP1L" MicroRNA hsa-miR-210:mirSVR_highEffct hsa-miR-210:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.05E-05 2.73E-01 9.02E-05 8.27E-04 11 194 "WLS,TOMM40L,ST3GAL3,SLC8A3,ZFP91,HMGB1,SEMA5B,CNRIP1,KCNK1,KCNK2,EFNA3" MicroRNA hsa-miR-146b-5p:TargetScan hsa-miR-146b-5p TargetScan 5.05E-05 2.73E-01 9.02E-05 8.27E-04 11 194 "ACER3,MAPT,RCSD1,SCN3B,GRID1,CELF3,KCNK10,POU3F2,MED1,IGSF1,KCND3" MicroRNA hsa-miR-146a-5p:TargetScan hsa-miR-146a-5p TargetScan 5.05E-05 2.73E-01 9.02E-05 8.27E-04 11 194 "ACER3,MAPT,RCSD1,SCN3B,GRID1,CELF3,KCNK10,POU3F2,MED1,IGSF1,KCND3" MicroRNA hsa-miR-518a-5p:Functional MTI Functional MTI miRTarbase 5.13E-05 2.78E-01 9.16E-05 8.40E-04 10 161 "MAPT,FOXRED2,GAS7,CCDC80,UNC5D,PRUNE2,FAM69C,CRLS1,KIAA0513,RAVER2" MicroRNA hsa-miR-6516-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.17E-05 2.80E-01 9.23E-05 8.46E-04 22 650 "ACER3,PLEKHG5,SEMA6A,SLC30A10,MAGI3,CCDC80,KBTBD12,SCN3B,CAB39,GNG4,PTBP2,NUCB1,RFFL,TPM3,SCRG1,JAM2,CCSER2,FAT3,ACBD5,KIAA0513,HP1BP3,DNAH9" MicroRNA "CAGCCTC,MIR-485-5P:MSigDB" "CAGCCTC,MIR-485-5P:MSigDB" MSigDB 5.23E-05 2.83E-01 9.32E-05 8.55E-04 9 130 "LRRC7,WDTC1,SOX5,NUCB1,GRIN1,ZFP91,SF1,KCNA6,KCNJ11" MicroRNA hsa-miR-768-5p:PITA hsa-miR-768-5p:PITA_TOP PITA 5.23E-05 2.83E-01 9.32E-05 8.55E-04 9 130 "WLS,MYBPC1,EML4,VXN,GUCY1A2,RAB5B,FAM57B,PHC2,EPB41" MicroRNA hsa-miR-497-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-05 2.83E-01 9.33E-05 8.56E-04 8 101 "ADARB2,KIAA1109,SLC1A2,NFASC,GANAB,MAPK8,DPP6,EFNA3" MicroRNA hsa-miR-1468-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.27E-05 2.86E-01 9.40E-05 8.62E-04 13 267 "ADARB2,CDC42BPA,CCDC80,SPART,PTBP2,BTF3L4,ACBD5,PRKACB,MAPK8,KIAA0513,ARHGAP12,RAVER2,RCAN2" MicroRNA hsa-miR-1247-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.29E-05 2.87E-01 9.43E-05 8.65E-04 15 345 "ECSIT,MDM4,PLEKHG5,ANK1,SLC7A14,KIAA1614,SFMBT2,SLC2A5,INKA2,RFFL,HMGB1,CCSER2,KIAA0408,KIAA0513,PARP11" MicroRNA hsa-miR-378a-5p:Functional MTI Functional MTI miRTarbase 5.32E-05 2.88E-01 9.48E-05 8.70E-04 16 386 "SLC25A25,ASTN1,C10orf105,ATM,NODAL,CACNB2,CYB561A3,P2RX7,MEAF6,ATCAY,PLD5,FGFR1OP2,RABGAP1L,KCNN3,SSPN,UEVLD" MicroRNA hsa-miR-571:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.39E-05 2.92E-01 9.60E-05 8.81E-04 7 75 "RABEPK,HMGB1,SF1,PUM1,PMEPA1,NKAIN1,RAB5B" MicroRNA hsa-miR-1247:mirSVR_lowEffct hsa-miR-1247:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.41E-05 2.93E-01 9.62E-05 8.83E-04 14 306 "WAC,DISP3,CAPRIN2,RND1,AJAP1,ADGRL3,BRSK2,GRIA1,GRIN1,CD81,PDE2A,PRMT8,PHACTR3,DNM2" MicroRNA hsa-miR-3941:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.49E-05 2.97E-01 9.76E-05 8.96E-04 17 429 "CSMD2,ADCYAP1R1,CHST15,MOBP,SGIP1,WDTC1,AJAP1,UBTF,SF1,CRLS1,RIMS3,LRP8,MED24,KCNA4,KCNK1,SFXN5,FGFBP3" MicroRNA hsa-miR-4713-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-05 3.00E-01 9.85E-05 9.04E-04 11 196 "TUBB4A,SLIT1,ZCCHC24,ZNF638,ACSL6,NEURL1,ZDHHC22,PADI2,CDH8,DPYSL5,EPB41L1" MicroRNA hsa-miR-1273:mirSVR_highEffct hsa-miR-1273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.54E-05 3.00E-01 9.85E-05 9.04E-04 11 196 "LRRC7,CNIH2,SFMBT2,SLN,TNIK,SOX10,NCDN,CAMTA1,CACNB2,PDE4B,RNF220" MicroRNA hsa-miR-6858-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-05 3.00E-01 9.86E-05 9.05E-04 9 131 "MRVI1,WDTC1,NMNAT2,TNS1,SF1,C1orf109,WIPF2,BSCL2,EN2" MicroRNA hsa-miR-4285:mirSVR_lowEffct hsa-miR-4285:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.62E-05 3.04E-01 9.97E-05 9.15E-04 8 102 "SELL,ST3GAL3,ACSBG1,PTBP2,GRIA1,MFSD4A,ANKS1B,RGMA" MicroRNA hsa-miR-8068:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.62E-05 3.04E-01 9.97E-05 9.15E-04 8 102 "FGF14,SESN3,SALL3,OPCML,TNS1,NCAN,KIAA0408,JAKMIP2" MicroRNA hsa-miR-4671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.62E-05 3.04E-01 9.97E-05 9.15E-04 8 102 "CLIP1,CAPRIN2,SPART,PRUNE2,ACBD5,CEP170,WIPF2,UEVLD" MicroRNA hsa-miR-3685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.62E-05 3.04E-01 9.97E-05 9.15E-04 8 102 "CDHR1,MRVI1,SESN3,GAS7,TCF7L2,SYT6,EN2,EPB41" MicroRNA hsa-miR-192-5p:TargetScan hsa-miR-192-5p TargetScan 5.69E-05 3.08E-01 1.01E-04 9.26E-04 10 163 "PKP4,CLSTN1,KIF1B,RAP1GAP2,RFFL,ARHGAP19,FTO,PRKACB,KCNK1,PLEKHO1" MicroRNA hsa-miR-215-5p:TargetScan hsa-miR-215-5p TargetScan 5.69E-05 3.08E-01 1.01E-04 9.26E-04 10 163 "PKP4,CLSTN1,KIF1B,RAP1GAP2,RFFL,ARHGAP19,FTO,PRKACB,KCNK1,PLEKHO1" MicroRNA hsa-miR-369-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.08E-01 1.01E-04 9.26E-04 10 163 "ADD3,CCDC80,MYBPC1,NAP1L2,LUZP2,CAMSAP2,SLC25A27,SPIRE1,PMEPA1,KLRC3" MicroRNA hsa-miR-1248:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.08E-01 1.01E-04 9.26E-04 10 163 "NLGN4X,SFMBT2,GFRA1,FAM69C,NUCB1,TNS1,HMGB1,NEGR1,MEAF6,ZYG11B" MicroRNA hsa-miR-5010-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-05 3.08E-01 1.01E-04 9.26E-04 10 163 "CLIP1,FGF14,CCDC80,ASTN2,ZEB1,COL9A2,ACBD5,NCAN,JAKMIP2,ZC3H11A" MicroRNA hsa-miR-1280:PITA hsa-miR-1280:PITA_TOP PITA 5.73E-05 3.10E-01 1.02E-04 9.32E-04 4 17 "NRXN2,CAMKV,CTNND1,DLG2" MicroRNA hsa-miR-8063:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-05 3.14E-01 1.03E-04 9.42E-04 11 197 "MAPT,ADCYAP1R1,CDC42BPA,KIAA1614,TCF7L2,NUDT21,PDE1A,CCSER2,BTF3L4,TENM4,ARHGAP12" MicroRNA hsa-miR-224-5p:Functional MTI Functional MTI miRTarbase 5.89E-05 3.19E-01 1.04E-04 9.56E-04 9 132 "F3,API5,SLC7A14,VXN,CDC42,TPD52,TOMM20,CACNG7,EFNA3" MicroRNA hsa-miR-671-3p:mirSVR_lowEffct hsa-miR-671-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.91E-05 3.20E-01 1.05E-04 9.59E-04 13 270 "DPF1,FGF1,TACC2,SYBU,TTLL9,ADHFE1,WSCD1,GRIA4,GPR88,PTPN5,FMN2,KCNMA1,EN2" MicroRNA hsa-miR-6087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.91E-05 3.20E-01 1.05E-04 9.59E-04 13 270 "ECSIT,MDM4,PLEKHG5,KBTBD12,GNG4,TPM3,JAM2,PIK3CD,A2ML1,PACSIN1,MICAL2,KIAA0513,PHYHIP" MicroRNA hsa-miR-454*:mirSVR_highEffct hsa-miR-454*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.00E-05 3.25E-01 1.06E-04 9.74E-04 14 309 "CSMD2,GRAMD1B,CACHD1,MSR1,KIRREL3,FAM168A,CACNB2,VSTM2A,NRSN1,C1orf109,PEX5,TMEM255A,RAVER2,EPB41L2" MicroRNA hsa-miR-6506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.01E-05 3.25E-01 1.06E-04 9.74E-04 16 390 "FOXRED2,EMC1,BCL2L2,AJAP1,ACSBG1,WWC1,MFSD2A,HMGB1,NEGR1,COL9A2,ATCAY,RGS6,OCIAD1,KCND3,RABGAP1L,ABI2" MicroRNA hsa-miR-1286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.02E-05 3.26E-01 1.06E-04 9.76E-04 8 103 "ADAR,KIAA1109,FXYD6,GJB1,DDR1,NCAN,BLOC1S6,EN2" MicroRNA hsa-miR-4667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.02E-05 3.26E-01 1.06E-04 9.76E-04 8 103 "CLSTN1,LHFPL4,GPR26,USP2,TLX1,RGS6,WBP1L,KCNN3" MicroRNA hsa-miR-196a:PITA hsa-miR-196a:PITA_TOP PITA 6.07E-05 3.29E-01 1.07E-04 9.83E-04 11 198 "SYT9,GAS7,SLC8A2,RAP1GAP2,ACSL6,PTBP2,OPCML,RGS6,ATRNL1,BLOC1S6,EPB41L2" MicroRNA hsa-miR-196b:PITA hsa-miR-196b:PITA_TOP PITA 6.07E-05 3.29E-01 1.07E-04 9.83E-04 11 198 "SYT9,GAS7,SLC8A2,RAP1GAP2,ACSL6,PTBP2,OPCML,RGS6,ATRNL1,BLOC1S6,EPB41L2" MicroRNA hsa-miR-4632-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-05 3.38E-01 1.10E-04 1.01E-03 9 133 "SLC6A9,GJB1,TMPRSS5,PACSIN1,PMEPA1,C1orf109,KCNH1,DNM2,SH3GLB1" MicroRNA hsa-miR-7843-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-05 3.38E-01 1.10E-04 1.01E-03 9 133 "SLC6A9,GJB1,TMPRSS5,PACSIN1,PMEPA1,C1orf109,KCNH1,DNM2,SH3GLB1" MicroRNA hsa-miR-3195:mirSVR_lowEffct hsa-miR-3195:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.24E-05 3.38E-01 1.10E-04 1.01E-03 9 133 "NTNG1,NAXD,ADHFE1,DCLK2,SULT4A1,CELF5,NECAB2,MAGI2,STMN4" MicroRNA hsa-let-7e-5p:Functional MTI Functional MTI miRTarbase 6.26E-05 3.39E-01 1.10E-04 1.01E-03 21 612 "ARID1A,MDM4,TUBB4A,TOMM40L,SCMH1,RCOR3,SALL3,BTRC,GPM6B,PSD3,TGFBR3,RBFOX2,ARHGAP19,HMGB1,ARNT2,DNAH9,C12orf4,BSDC1,JMJD1C,EN2,PLEKHO1" MicroRNA hsa-miR-6513-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.38E-05 3.45E-01 1.12E-04 1.03E-03 16 392 "MDM4,SOX6,CCDC80,CLSTN1,SLC1A2,LRRC55,SLC6A9,DNAH17,GNG4,GRIK2,ZFP91,FTO,FAT3,DNAH9,RAB5B,ABI2" MicroRNA hsa-miR-151a-3p:TargetScan hsa-miR-151a-3p TargetScan 6.39E-05 3.46E-01 1.13E-04 1.03E-03 7 77 "ATM,NPAS3,CLASP2,FTO,ELMO1,CALN1,EFNA3" MicroRNA hsa-miR-4260:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-05 3.46E-01 1.13E-04 1.03E-03 7 77 "MDM4,DRAXIN,NMNAT2,CACNB2,MEAF6,MAPK10,DNAJC6" MicroRNA hsa-miR-5572:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-05 3.46E-01 1.13E-04 1.03E-03 7 77 "MDM4,DRAXIN,NMNAT2,CACNB2,MEAF6,MICAL2,MAPK10" MicroRNA hsa-miR-877-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.44E-05 3.49E-01 1.13E-04 1.04E-03 12 235 "DGKD,USP33,CAB39,BCL2L2,CECR2,USP2,ZFP91,BTF3L4,MAPK8,PROX1,TUBB2B,C12orf4" MicroRNA hsa-miR-708-5p:Functional MTI Functional MTI miRTarbase 6.45E-05 3.49E-01 1.14E-04 1.04E-03 8 104 "PLEKHG5,TUBB4A,DRAXIN,FAM168A,ZFP91,NOS1AP,PRDM2,PIANP" MicroRNA hsa-miR-605-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-05 3.58E-01 1.16E-04 1.07E-03 9 134 "SDE2,SMARCE1,BTRC,CD81,CTNND1,FAM131B,BLOC1S6,RAB5B,PHC2" MicroRNA hsa-miR-5192:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-05 3.58E-01 1.16E-04 1.07E-03 9 134 "ZFYVE27,PDZD4,PKNOX2,C10orf105,NEUROD1,TMPRSS5,ZC3H11A,NKAIN1,RAB5B" MicroRNA hsa-miR-337-5p:mirSVR_highEffct hsa-miR-337-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.64E-05 3.60E-01 1.17E-04 1.07E-03 11 200 "LINC00461,SESN3,SYBU,NLGN1,PAAF1,SLCO1A2,KIF1B,TJP1,PPP2R5C,PTPRO,ZYG11B" MicroRNA hsa-miR-744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.68E-05 3.62E-01 1.18E-04 1.08E-03 17 436 "DPF1,LDLRAD3,PLEKHG5,FOXRED2,HPCAL4,ARHGAP5,ZCCHC24,GART,INKA2,CACNA1A,NRGN,TUB,MICAL2,CHD5,PHC2,EEF1A2,EN2" MicroRNA "GTTTGTT,MIR-495:MSigDB" "GTTTGTT,MIR-495:MSigDB" MSigDB 6.70E-05 3.63E-01 1.18E-04 1.08E-03 12 236 "SOX6,ARHGAP5,ATP2B2,WDTC1,MYT1L,SOX5,GPM6A,EML4,CAMK2G,RIMS4,NTM,RPRD1A" MicroRNA hsa-miR-4537:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-05 3.73E-01 1.21E-04 1.11E-03 14 313 "ATAT1,PLEKHG5,DRAXIN,SLC30A10,ATM,SCN3B,EMC1,RAP1GAP2,TPM3,ADGRG1,CCSER2,DOCK7,EPB41,EPB41L1" MicroRNA hsa-miR-6880-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-05 3.73E-01 1.21E-04 1.11E-03 14 313 "PNMA8B,PDZD4,ASTN2,PTBP2,CECR2,BTF3L4,PACSIN1,FAT3,KIAA0513,SIRPA,HP1BP3,PARP11,GNE,EN2" MicroRNA "GTAAGAT,MIR-200A:MSigDB" "GTAAGAT,MIR-200A:MSigDB" MSigDB 6.92E-05 3.75E-01 1.21E-04 1.11E-03 6 54 "NSG2,ARPP21,NFIA,PAX6,HMGB1,NSD2" MicroRNA "CAGGGTC,MIR-504:MSigDB" "CAGGGTC,MIR-504:MSigDB" MSigDB 6.94E-05 3.76E-01 1.22E-04 1.12E-03 7 78 "CAMK2G,GRM3,USP2,CEP170,NTM,VANGL2,EPB41" MicroRNA hsa-miR-1303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.95E-05 3.76E-01 1.22E-04 1.12E-03 11 201 "SLC30A10,API5,SON,NUCB1,GRIK2,ZNF384,FAT3,PLD5,USP54,GNE,ZYG11B" MicroRNA hsa-miR-510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-05 3.78E-01 1.22E-04 1.12E-03 10 167 "FAM43B,SGIP1,SON,AJAP1,ZFP91,PAX6,MFSD4A,KCNJ4,ARHGAP12,ELAVL4" MicroRNA hsa-miR-6735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-05 3.80E-01 1.23E-04 1.13E-03 9 135 "SLC6A9,GJB1,TMPRSS5,PACSIN1,PMEPA1,C1orf109,KCNH1,DNM2,SH3GLB1" MicroRNA hsa-miR-3689d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.28E-05 3.94E-01 1.28E-04 1.17E-03 15 355 "ANK1,SLC2A5,ASPH,FXYD6,DDR1,PTBP2,FAT3,ACBD5,NOS1AP,KIAA0513,SIRPA,HP1BP3,PLEKHB2,PARP11,SSPN" MicroRNA hsa-miR-4700-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.38E-05 4.00E-01 1.29E-04 1.19E-03 8 106 "CLSTN1,LHFPL4,GPR26,USP2,TLX1,RGS6,WBP1L,KCNN3" MicroRNA "GCTTGAA,MIR-498:MSigDB" "GCTTGAA,MIR-498:MSigDB" MSigDB 7.38E-05 4.00E-01 1.29E-04 1.19E-03 8 106 "ITSN1,PKNOX2,EML4,CAMK2G,PSD3,GRIA2,TMEM257,PDE4B" MicroRNA hsa-miR-5584-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-05 4.08E-01 1.32E-04 1.21E-03 7 79 "SLC30A10,CCDC80,SMOC1,ACSL6,TNS1,DOCK7,SH3GLB1" MicroRNA hsa-miR-6832-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.61E-05 4.12E-01 1.33E-04 1.22E-03 14 316 "ADCYAP1R1,TMEM156,ADORA3,LRRC55,ZCCHC24,SMOC1,MYRF,TCF7L2,SYT6,BRSK2,CDH8,SLC22A6,CHD5,UEVLD" MicroRNA hsa-miR-1291:Functional MTI Functional MTI miRTarbase 7.68E-05 4.16E-01 1.34E-04 1.23E-03 6 55 "INKA2,GANAB,PFKFB3,CHRNB2,VANGL2,VWA5A" MicroRNA hsa-miR-3972:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-05 4.16E-01 1.34E-04 1.23E-03 6 55 "ADD3,SFMBT2,MEAF6,CTNND1,CSDE1,PAK5" MicroRNA hsa-miR-4436b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-05 4.25E-01 1.37E-04 1.26E-03 9 137 "SLC6A9,GJB1,TMPRSS5,PACSIN1,PMEPA1,C1orf109,KCNH1,DNM2,SH3GLB1" MicroRNA hsa-miR-924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-05 4.27E-01 1.38E-04 1.27E-03 8 107 "ELMOD1,MOG,C1orf61,TMEM136,VXN,BTF3L4,PLD5,ZYG11B" MicroRNA "ATACCTC,MIR-202:MSigDB" "ATACCTC,MIR-202:MSigDB" MSigDB 8.10E-05 4.38E-01 1.42E-04 1.30E-03 10 170 "SHANK2,KIF1B,CACNA1E,RBFOX2,ZC3H11A,SRGAP3,SNX27,ATG16L1,VANGL2,ELAVL3" MicroRNA hsa-miR-3152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.16E-05 4.42E-01 1.43E-04 1.31E-03 7 80 "LRRC55,AJAP1,NUCB1,POU3F2,KCNK1,RAB5B,ABI2" MicroRNA hsa-miR-614:mirSVR_highEffct hsa-miR-614:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.28E-05 4.49E-01 1.45E-04 1.33E-03 11 205 "ADD3,TOMM40L,TNIK,LUZP2,CCKBR,PFKFB3,CNRIP1,CTNND2,CSDE1,SUSD4,SLC4A10" MicroRNA hsa-miR-6879-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-05 4.50E-01 1.45E-04 1.33E-03 9 138 "SLC6A9,GJB1,TMPRSS5,PACSIN1,PMEPA1,C1orf109,KCNH1,DNM2,SH3GLB1" MicroRNA hsa-miR-4520-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.33E-05 4.51E-01 1.45E-04 1.33E-03 5 35 "TTYH1,ABAT,RAB5B,CALN1,EN2" MicroRNA hsa-miR-4693-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.43E-05 4.56E-01 1.47E-04 1.35E-03 8 108 "ZFYVE27,KLHL32,TMEM136,TMPRSS5,PTPA,ARHGEF4,NKAIN1,RAB5B" MicroRNA "GGTGAAG,MIR-412:MSigDB" "GGTGAAG,MIR-412:MSigDB" MSigDB 8.51E-05 4.61E-01 1.48E-04 1.36E-03 6 56 "SOX6,ANK2,PKP4,WDTC1,BTRC,CSDE1" MicroRNA hsa-miR-580-3p:Functional MTI Functional MTI miRTarbase 8.78E-05 4.75E-01 1.53E-04 1.40E-03 9 139 "ACER3,SRARP,MIER1,CAB39,ACSL6,RNF14,PRKAB2,TOMM20,WIPF2" MicroRNA hsa-miR-633:Functional MTI Functional MTI miRTarbase 8.84E-05 4.78E-01 1.54E-04 1.41E-03 7 81 "SDE2,MAGI3,NAXD,SON,DDR2,CEP170,SH3GLB1" MicroRNA hsa-miR-127-3p:mirSVR_highEffct hsa-miR-127-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.84E-05 4.78E-01 1.54E-04 1.41E-03 7 81 "ATP1A2,TLX1,JAM2,P2RY12,PKN2,PSMD13,KCNK2" MicroRNA hsa-miR-1226-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.84E-05 4.78E-01 1.54E-04 1.41E-03 7 81 "CHST15,SLC2A5,ASTN1,SMOC1,TPD52,PHYHIP,ARHGAP12" MicroRNA hsa-miR-1229-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.03E-05 4.89E-01 1.57E-04 1.44E-03 11 207 "ACLY,SFPQ,AHCYL1,ZDHHC22,ACOT7,HNRNPK,CTNND1,JAKMIP2,PMEPA1,CSDE1,EPB41L2" MicroRNA hsa-miR-520g-3p:Functional MTI Functional MTI miRTarbase 9.05E-05 4.90E-01 1.58E-04 1.45E-03 16 404 "MAPT,FOXRED2,DRAXIN,BCL2L2,WWC1,PRUNE2,MFSD2A,P2RX7,KCNK10,HMGB1,NSD2,PROX1,OCIAD1,KCND3,RABGAP1L,ST8SIA3" MicroRNA hsa-miR-1280:mirSVR_highEffct hsa-miR-1280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.40E-05 5.09E-01 1.64E-04 1.50E-03 6 57 "ASRGL1,PKP4,GRM3,CAMKV,FEZ2,RBPJ" MicroRNA hsa-miR-4763-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.48E-05 5.13E-01 1.65E-04 1.51E-03 13 283 "WAC,PNMA8B,TUBB4A,AMER2,TMEM151A,GJB1,BRSK2,TMPRSS5,PACSIN1,FAM131B,KIAA0513,DPYSL5,TOMM20" MicroRNA hsa-miR-1914:mirSVR_highEffct hsa-miR-1914:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.53E-05 5.16E-01 1.66E-04 1.52E-03 17 449 "EPS8,MDM4,ITSN1,RUFY2,CAPRIN2,GAD2,NCAM1,CECR2,GRIA2,CCKBR,PCDH8,TPM3,DUSP26,PLXNB3,DOCK7,PSMD13,PRDM2" MicroRNA hsa-miR-4323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.55E-05 5.17E-01 1.66E-04 1.52E-03 7 82 "RTKN,PKNOX2,BCL2L2,NRGN,SIRPA,WIPF2,ELAVL3" MicroRNA hsa-miR-24-1-5p:Functional MTI Functional MTI miRTarbase 9.57E-05 5.18E-01 1.66E-04 1.53E-03 5 36 "SLITRK1,FOXM1,TPM4,PNKD,ABI2" MicroRNA hsa-miR-374c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.57E-05 5.18E-01 1.66E-04 1.53E-03 5 36 "MDM4,CAMSAP2,HMGB1,TUB,FMN2" MicroRNA hsa-miR-8089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.59E-05 5.19E-01 1.67E-04 1.53E-03 8 110 "CLSTN1,LHFPL4,GPR26,USP2,TLX1,RGS6,WBP1L,KCNN3" MicroRNA hsa-miR-4793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-05 5.30E-01 1.70E-04 1.56E-03 9 141 "MAPT,SLC25A25,BCAN,SLC1A7,GNAS,DAAM2,HMGB1,KIAA1549L,WIPF2" MicroRNA hsa-miR-519d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-05 5.30E-01 1.70E-04 1.56E-03 9 141 "CAB39,INKA2,NFIA,CACNA1A,REPS2,PTGDR2,PDE1A,FGFR1OP2,ZNF248" MicroRNA hsa-miR-588:PITA hsa-miR-588:PITA_TOP PITA 9.80E-05 5.30E-01 1.70E-04 1.56E-03 9 141 "SOX5,PDE3B,PPP2R5C,DOCK7,PKN2,STMN4,ZC3H11A,PTPRO,SNX27" MicroRNA hsa-miR-8064:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-05 5.30E-01 1.70E-04 1.56E-03 9 141 "ATAT1,SLC25A25,CADPS,CADM3,EMC1,NDUFA5,INKA2,GRIK3,UBTF" MicroRNA hsa-miR-5692b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.82E-05 5.32E-01 1.70E-04 1.56E-03 10 174 "ADD3,CCDC80,MYBPC1,LUZP2,DDHD2,CAMSAP2,SLC25A27,BTF3L4,PMEPA1,KLRC3" MicroRNA hsa-miR-5692c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.82E-05 5.32E-01 1.70E-04 1.56E-03 10 174 "ADD3,CCDC80,MYBPC1,LUZP2,DDHD2,CAMSAP2,SLC25A27,BTF3L4,PMEPA1,KLRC3" MicroRNA hsa-miR-223-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.82E-05 5.32E-01 1.70E-04 1.56E-03 13 284 "NLGN4X,FGF14,SOX5,TMEM151B,LRTM2,CCSER2,SPATA6,ACBD5,DOCK7,PROX1,JAKMIP2,SSPN,ABI2" MicroRNA hsa-miR-520h:Functional MTI Functional MTI miRTarbase 9.85E-05 5.33E-01 1.71E-04 1.57E-03 16 407 "MAPT,FOXRED2,DRAXIN,BCL2L2,WWC1,PRUNE2,MFSD2A,P2RX7,KCNK10,HMGB1,NSD2,PROX1,OCIAD1,KCND3,RABGAP1L,ST8SIA3" MicroRNA hsa-miR-4652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-04 5.53E-01 1.77E-04 1.62E-03 8 111 "ARID1A,FOXG1,MIER1,SFMBT2,SOX1,GRIK4,DPP6,TTLL7" MicroRNA hsa-miR-431-5p:TargetScan hsa-miR-431-5p TargetScan 1.02E-04 5.53E-01 1.77E-04 1.62E-03 8 111 "CCDC88A,NSG2,AIFM1,C1orf94,CCSER2,BTF3L4,RAB5B,EPB41L1" MicroRNA hsa-miR-720:mirSVR_highEffct hsa-miR-720:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-04 5.53E-01 1.77E-04 1.62E-03 8 111 "FOXG1,ST3GAL3,PRLHR,PRMT8,FEZ1,RBPJ,RASGRF1,ROM1" MicroRNA hsa-miR-615-5p:mirSVR_highEffct hsa-miR-615-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-04 5.54E-01 1.77E-04 1.63E-03 14 325 "TUBB4A,STK32C,PKNOX2,NCAM1,DDR1,ADAMTS8,TPM3,PLEKHB1,SNCAIP,PRKCZ,MAPK10,MASP1,DNAJC6,PEX5" MicroRNA hsa-miR-3150a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.57E-01 1.78E-04 1.63E-03 10 175 "DRAXIN,CLSTN1,LHFPL4,FAM168A,CACNB2,DIRAS1,UBTF,PTPA,RGS6,PHYHIP" MicroRNA hsa-miR-1206:PITA hsa-miR-1206:PITA_TOP PITA 1.03E-04 5.57E-01 1.78E-04 1.63E-03 10 175 "SCN3A,SOX6,SHTN1,ARHGAP5,CAMTA1,CAMSAP2,GPR88,CDH10,BRINP3,ITGAV" MicroRNA hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 1.03E-04 5.57E-01 1.78E-04 1.63E-03 10 175 "FGF14,NSG2,NPAS3,C11orf87,GFRA1,KAZN,CAMK2G,KCNK10,MED1,RAVER2" MicroRNA hsa-miR-6763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.57E-01 1.78E-04 1.63E-03 10 175 "DRAXIN,CLSTN1,LHFPL4,FAM168A,CACNB2,DIRAS1,UBTF,PTPA,RGS6,PHYHIP" MicroRNA hsa-miR-3529-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.59E-01 1.78E-04 1.63E-03 7 83 "EPS8,MDM4,ALDH4A1,TPD52,BEST3,MICAL2,ZYG11B" MicroRNA hsa-miR-339-3p:mirSVR_highEffct hsa-miR-339-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-04 5.59E-01 1.78E-04 1.63E-03 7 83 "UNC79,ADHFE1,PRMT8,GDAP1L1,PNKD,TMCC2,SEC61A2" MicroRNA hsa-miR-21-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.59E-01 1.78E-04 1.63E-03 7 83 "GPAM,SON,CDC42,SF1,ELMO1,L1CAM,SH3GLB1" MicroRNA hsa-miR-769-5p:PITA hsa-miR-769-5p:PITA_TOP PITA 1.03E-04 5.59E-01 1.78E-04 1.63E-03 7 83 "ARID1A,SLITRK1,VAMP1,PSD3,TPD52,KCNMA1,ABI1" MicroRNA hsa-miR-6840-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-04 5.59E-01 1.78E-04 1.63E-03 17 452 "SLC30A10,MAGI3,ATM,ACSBG1,VAMP1,GNG3,GNG4,ACSL6,NRGN,GPR37L1,FAT3,ACBD5,RNF14,FGFR1OP2,HP1BP3,DNAH9,DNM2" MicroRNA hsa-miR-1202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.62E-01 1.79E-04 1.64E-03 6 58 "ADD3,SFMBT2,MEAF6,CTNND1,CSDE1,PAK5" MicroRNA hsa-miR-943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.62E-01 1.79E-04 1.64E-03 6 58 "FGF1,DDR2,DAAM2,ST8SIA5,FEZ2,CADM2" MicroRNA hsa-miR-647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.62E-01 1.79E-04 1.64E-03 6 58 "MRVI1,SLC25A25,ANK2,MAGI3,SLC1A7,CACNA1A" MicroRNA hsa-miR-7154-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.62E-01 1.79E-04 1.64E-03 6 58 "NBPF1,ERBIN,KLHL4,RBFOX2,MAPK8,PRDM2" MicroRNA "AGTCAGC,MIR-345:MSigDB" "AGTCAGC,MIR-345:MSigDB" MSigDB 1.04E-04 5.62E-01 1.79E-04 1.64E-03 6 58 "EPS8,SCMH1,KIF1B,NFIA,CACNB2,NXPH1" MicroRNA hsa-miR-197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.64E-01 1.80E-04 1.65E-03 16 409 "SERPINA3,ADAR,ATP1A2,KIF1B,SPART,ZNF302,GOLGB1,GPR26,CYB561A3,ZDHHC22,ZNF384,MED24,GNE,ZYG11B,RAVER2,UEVLD" MicroRNA hsa-miR-483-3p:Functional MTI Functional MTI miRTarbase 1.08E-04 5.84E-01 1.86E-04 1.70E-03 10 176 "PALLD,CAMK2G,TMEM151B,BEST3,HPR,KIAA0408,DPYSL5,RAB5B,RASGRF1,FGFBP3" MicroRNA "TCCAGAG,MIR-518C:MSigDB" "TCCAGAG,MIR-518C:MSigDB" MSigDB 1.09E-04 5.91E-01 1.88E-04 1.72E-03 9 143 "ANK2,RND1,TCF12,PCDHGA3,CAMK2G,CDC42,PCDH9,NRXN2,PUM1" MicroRNA hsa-miR-412-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.09E-04 5.91E-01 1.88E-04 1.72E-03 9 143 "SRARP,DGKD,SON,CYB561A3,GUCY1A1,PNKD,CSDE1,CALN1,EEF1A2" MicroRNA hsa-miR-516b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-04 6.03E-01 1.91E-04 1.76E-03 7 84 "TMEM151A,NASP,GNAS,MYRF,PRRX1,PLD5,C1orf109" MicroRNA hsa-miR-1295b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-04 6.03E-01 1.91E-04 1.76E-03 7 84 "KIAA1614,IGSF9B,EMC1,CAMSAP2,FAT3,CADM2,RAB5B" MicroRNA hsa-miR-181d-5p:Functional MTI Functional MTI miRTarbase 1.13E-04 6.11E-01 1.94E-04 1.78E-03 13 288 "EPS8,MEG3,SLC25A25,CAPRIN2,ATM,NRDC,HMGB1,NMT2,NSD2,PNKD,OSBPL3,SPIRE1,EN2" MicroRNA hsa-miR-1207-5p:Functional MTI Functional MTI miRTarbase 1.13E-04 6.11E-01 1.94E-04 1.78E-03 13 288 "WAC,PNMA8B,TUBB4A,AMER2,TMEM151A,GJB1,BRSK2,TMPRSS5,PACSIN1,FAM131B,KIAA0513,DPYSL5,TOMM20" MicroRNA hsa-miR-1910-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-04 6.19E-01 1.96E-04 1.80E-03 6 59 "SLC1A2,DNAH17,KIF21B,NASP,TMEM151B,KCNK10" MicroRNA hsa-miR-4463:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-04 6.50E-01 2.06E-04 1.89E-03 7 85 "RTKN,SLC6A9,YPEL4,GRM3,SPATA6,PTPA,PTAFR" MicroRNA hsa-miR-379-5p:Functional MTI Functional MTI miRTarbase 1.20E-04 6.50E-01 2.06E-04 1.89E-03 7 85 "EPS8,MDM4,ALDH4A1,TPD52,BEST3,MICAL2,ZYG11B" MicroRNA hsa-miR-7159-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-04 6.50E-01 2.06E-04 1.89E-03 7 85 "MYBPC1,SOX1,SYT4,TCF7L2,FBXL16,NEGR1,RIMS4" MicroRNA hsa-miR-33a-5p:Functional MTI Functional MTI miRTarbase 1.24E-04 6.71E-01 2.13E-04 1.95E-03 10 179 "RTN3,PALLD,ERBIN,TNS1,MAPK8,PTHLH,KCNK1,RTN4,BSDC1,EN2" MicroRNA hsa-miR-548ah-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-04 6.77E-01 2.14E-04 1.97E-03 13 291 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-548am-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-04 6.77E-01 2.14E-04 1.97E-03 13 291 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-6779-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-04 6.80E-01 2.15E-04 1.98E-03 6 60 "TMEM136,DDR2,KCNK10,TPM3,KCNJ11,EPB41" MicroRNA hsa-miR-1255a:PITA hsa-miR-1255a:PITA_TOP PITA 1.29E-04 6.99E-01 2.21E-04 2.03E-03 7 86 "GPAM,NLGN1,CAMTA1,CAMK2G,FNDC5,RIMS3,LRRTM3" MicroRNA hsa-miR-1255b:PITA hsa-miR-1255b:PITA_TOP PITA 1.29E-04 6.99E-01 2.21E-04 2.03E-03 7 86 "GPAM,NLGN1,CAMTA1,CAMK2G,FNDC5,RIMS3,LRRTM3" MicroRNA hsa-miR-3921:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-04 6.99E-01 2.21E-04 2.03E-03 7 86 "TOMM40L,TACC2,ACSL6,P2RX7,PRMT8,TLX1,PRKAB2" MicroRNA hsa-miR-3662:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-04 7.00E-01 2.21E-04 2.03E-03 12 253 "SRARP,MRVI1,MDM4,CLIP1,MYBPC1,SALL3,NFIA,NUDT21,CCSER2,MAPK8,CEP170,JMJD1C" MicroRNA hsa-miR-548j-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-04 7.00E-01 2.21E-04 2.03E-03 13 292 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-3161:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-04 7.08E-01 2.24E-04 2.05E-03 8 115 "GAS7,NUDT21,PAX6,CTNND1,TOMM20,WIPF2,CACNG7,ABI2" MicroRNA hsa-miR-616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-04 7.21E-01 2.28E-04 2.09E-03 15 375 "KIF1B,TMEM136,TCF7L2,RFFL,VWCE,OLR1,PTGDR2,GPR37L1,NRXN1,CCSER2,MAPK8,RABGAP1L,WIPF2,ARHGAP12,ELAVL4" MicroRNA hsa-miR-548ae-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.24E-01 2.29E-04 2.10E-03 13 293 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-548x-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.24E-01 2.29E-04 2.10E-03 13 293 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-548aj-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.24E-01 2.29E-04 2.10E-03 13 293 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-548aq-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.24E-01 2.29E-04 2.10E-03 13 293 "ARID1A,SNCB,MYBPC1,KIF1B,NUDT21,GRIK4,TGFBR3,TJP1,KCNK10,HMGB1,RIMS4,PKN2,ZYG11B" MicroRNA hsa-miR-181a*:mirSVR_highEffct hsa-miR-181a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-04 7.29E-01 2.30E-04 2.11E-03 9 147 "MIER1,SMARCE1,ATM,GLS,CACNB2,TNR,MAGI1,PRKCZ,KCNK2" MicroRNA hsa-miR-3613-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.45E-01 2.35E-04 2.16E-03 18 508 "SESN3,SLC14A1,IGSF9B,EIF4G3,TCF7L2,NUDT21,RFFL,OLR1,GPR37L1,BTF3L4,SLC36A4,FAT3,ATRNL1,MAPK8,KCNN3,WIPF2,BSDC1,ARHGAP12" MicroRNA hsa-miR-1247-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-04 7.49E-01 2.36E-04 2.17E-03 4 21 "WAC,TESK2,HPR,RIMS3" MicroRNA hsa-miR-658:PITA hsa-miR-658:PITA_TOP PITA 1.38E-04 7.49E-01 2.36E-04 2.17E-03 4 21 "SEMA6C,NRGN,CABP1,EEF1A2" MicroRNA hsa-miR-4653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-04 7.52E-01 2.37E-04 2.17E-03 7 87 "TOMM40L,TACC2,ACSL6,P2RX7,PRMT8,TLX1,PRKAB2" MicroRNA hsa-miR-3978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-04 7.52E-01 2.37E-04 2.17E-03 8 116 "BCAN,NASP,GNAS,CECR2,PLD5,CTNND1,KIAA0513,ABCC9" MicroRNA hsa-miR-105*:mirSVR_highEffct hsa-miR-105*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-04 7.52E-01 2.37E-04 2.17E-03 8 116 "NTNG1,B3GALT2,NELL1,GNAS,CHGA,HERC2P3,PRTFDC1,RFX4" MicroRNA hsa-miR-6771-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-04 7.53E-01 2.37E-04 2.17E-03 12 255 "HOGA1,MAGI3,CCDC80,LUZP2,BEST3,FAT3,SF1,ATRNL1,KIAA0513,CEP170,KCNJ4,RAB5B" MicroRNA hsa-miR-137:Non-Functional MTI Non-Functional MTI miRTarbase 1.42E-04 7.67E-01 2.41E-04 2.21E-03 9 148 "SERPINA3,USP28,CDC42,DCLK1,MED1,ZC3H11A,CALN1,RASGRF1,SFXN5" MicroRNA hsa-miR-3679-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-04 7.67E-01 2.41E-04 2.21E-03 9 148 "ACTN2,WAC,DKK3,NPAS3,DCAF5,INKA2,GPR26,TNS1,PTPRE" MicroRNA hsa-miR-6756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-04 7.69E-01 2.42E-04 2.22E-03 10 182 "CDHR1,WAC,SHANK2,NASP,DCAF5,DDR2,TENM4,FGFR1OP2,PMEPA1,CALN1" MicroRNA hsa-miR-505-3p.1:TargetScan hsa-miR-505-3p.1 TargetScan 1.43E-04 7.72E-01 2.43E-04 2.23E-03 11 218 "ABAT,ACTN2,KCNIP2,MIER1,MYT1L,CACNA1E,HMGB1,CADM1,NEGR1,KIAA0408,RFX4" MicroRNA hsa-miR-1909*:mirSVR_highEffct hsa-miR-1909*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-04 7.75E-01 2.43E-04 2.23E-03 13 295 "SDE2,ERICH3,APC,NTNG1,CAB39,GLS,MMD2,ADGRL3,TCF12,PTGDR2,CASC2,ATG16L1,ABI1" MicroRNA hsa-miR-3925-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-04 7.99E-01 2.51E-04 2.30E-03 8 117 "RUFY2,GFRA1,GPM6B,GRIK2,PRMT8,PLD5,SPIRE1,BLOC1S6" MicroRNA hsa-miR-216b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-04 7.99E-01 2.51E-04 2.30E-03 8 117 "ATAT1,DRAXIN,ANK3,EMC1,ZDHHC22,UBTF,MED24,ZYG11B" MicroRNA hsa-miR-431*:mirSVR_highEffct hsa-miR-431*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-04 8.04E-01 2.53E-04 2.32E-03 10 183 "SLITRK1,DRAXIN,FHL1,ELMOD1,PPFIA1,PKP4,SCG3,GABBR1,CRB1,FBXL16" MicroRNA "GTGACTT,MIR-224:MSigDB" "GTGACTT,MIR-224:MSigDB" MSigDB 1.57E-04 8.49E-01 2.66E-04 2.44E-03 9 150 "ITSN1,APBA2,API5,SEPT3,CDC42,FNDC5,HES5,KCNMA1,EFNA3" MicroRNA hsa-miR-1299:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-04 8.67E-01 2.72E-04 2.50E-03 7 89 "TMEM151A,GNAS,MYRF,NUDT21,PRRX1,C1orf109,EPB41" MicroRNA hsa-miR-619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.73E-01 2.74E-04 2.51E-03 16 425 "FOXRED2,EMC1,BCL2L2,AJAP1,ACSBG1,WWC1,MFSD2A,HMGB1,NEGR1,COL9A2,ATCAY,RGS6,OCIAD1,KCND3,RABGAP1L,ABI2" MicroRNA hsa-miR-513c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-04 8.79E-01 2.75E-04 2.53E-03 10 185 "SGIP1,ASCL1,TCF7L2,PSD3,NEGR1,CCSER2,SF1,PRKACB,CADM2,JMJD1C" MicroRNA hsa-miR-2355-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-04 8.79E-01 2.75E-04 2.53E-03 10 185 "NAXD,DKK3,INKA2,ZNF638,TBX15,CACNA1A,ARHGAP19,CTNND1,RIMS3,SIRPA" MicroRNA hsa-miR-5586-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-04 8.79E-01 2.75E-04 2.53E-03 10 185 "RABEPK,ZFYVE27,MAGI3,EMC1,OLR1,COL9A2,DOCK7,KCNN3,NKAIN1,RAB5B" MicroRNA hsa-miR-1302:PITA hsa-miR-1302:PITA_TOP PITA 1.65E-04 8.93E-01 2.80E-04 2.56E-03 9 151 "LGR4,NDRG2,SCN4B,SLITRK3,ATP2B2,LHFPL4,ACSL6,CAMK2G,MED1" MicroRNA hsa-miR-429:Functional MTI Functional MTI miRTarbase 1.65E-04 8.93E-01 2.80E-04 2.56E-03 9 151 "NLGN4X,CAB39,ERBIN,CAMSAP2,TCF7L2,ZEB1,PSD3,PTPRD,ABI2" MicroRNA hsa-miR-4496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-04 8.98E-01 2.81E-04 2.58E-03 8 119 "AMER2,LGI3,NFASC,NFIA,TPM4,KIAA0408,RTN4,SEZ6" MicroRNA hsa-miR-24-3p:Functional MTI Functional MTI miRTarbase 1.66E-04 9.01E-01 2.82E-04 2.59E-03 25 855 "MDM4,ADD3,DRAXIN,CLSTN1,SLC1A2,EIF4G3,NEK6,NASP,BCL2L2,ARHGEF7,DDHD2,OLR1,REPS2,ARHGAP19,MAGI1,ZFYVE9,NEGR1,NCAN,ZBTB16,PTAFR,COPS7A,MED24,KCNK2,TTLL7,EPB41" MicroRNA hsa-let-7c-5p:Functional MTI Functional MTI miRTarbase 1.67E-04 9.02E-01 2.82E-04 2.59E-03 18 516 "MDM4,TUBB4A,TOMM40L,CDC42BPA,CACHD1,SALL3,KIF1B,NUDT21,TGFBR3,RBFOX2,HES5,DNAJC6,DNAH9,RAB5B,C12orf4,BSDC1,EN2,PLEKHO1" MicroRNA hsa-miR-339-3p:PITA hsa-miR-339-3p:PITA_TOP PITA 1.67E-04 9.06E-01 2.83E-04 2.60E-03 4 22 "SALL3,BEST1,PNKD,RGS6" MicroRNA hsa-miR-200b-3p:Functional MTI Functional MTI miRTarbase 1.70E-04 9.18E-01 2.87E-04 2.63E-03 10 186 "NLGN4X,FOXG1,CAB39,ERBIN,CAMSAP2,TCF7L2,ZEB1,PSD3,PTPRD,ABI2" MicroRNA hsa-miR-6783-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-04 9.18E-01 2.87E-04 2.63E-03 10 186 "ZFYVE27,RTN3,JAKMIP3,PKNOX2,SPART,OLR1,TNS1,UBTF,SIRPA,TMCC2" MicroRNA hsa-miR-6509-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-04 9.30E-01 2.90E-04 2.66E-03 7 90 "PNMA8B,GRAMD1B,SESN3,PPP3CB,NOS1AP,CALN1,RCAN2" MicroRNA hsa-miR-652:mirSVR_highEffct hsa-miR-652:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-04 9.30E-01 2.90E-04 2.66E-03 7 90 "KLHL32,LGI1,NRSN1,TOX,KCNK2,DTNA,PHC2" MicroRNA hsa-miR-4477b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-04 9.30E-01 2.90E-04 2.66E-03 7 90 "SDE2,RUFY2,CAPRIN2,CAB39,SEPT3,CRB1,TPM4" MicroRNA hsa-miR-4709-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-04 9.30E-01 2.90E-04 2.66E-03 7 90 "WAC,BTRC,FBXL16,ARHGAP22,KCNN3,PARP11,RGR" MicroRNA hsa-miR-4795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.38E-01 2.93E-04 2.69E-03 9 152 "SYT9,ADARB2,CAMSAP2,DIRAS1,UBTF,PKN2,PLEKHB2,PHC2,EFNA3" MicroRNA hsa-miR-1296-5p:Functional MTI Functional MTI miRTarbase 1.76E-04 9.51E-01 2.97E-04 2.72E-03 8 120 "RTKN,TOMM40L,SFPQ,NFASC,BCL2L2,GANAB,NUDT21,CECR2" MicroRNA hsa-miR-610:PITA hsa-miR-610:PITA_TOP PITA 1.76E-04 9.51E-01 2.97E-04 2.72E-03 8 120 "PPM1E,PALLD,BCL2L2,ZNF384,KIAA1549L,MAGI2,PTPRD,RNF220" MicroRNA hsa-miR-513a-3p:Functional MTI Functional MTI miRTarbase 1.77E-04 9.59E-01 2.99E-04 2.74E-03 10 187 "SGIP1,ASCL1,TCF7L2,PSD3,NEGR1,CCSER2,SF1,PRKACB,CADM2,JMJD1C" MicroRNA hsa-miR-18a-5p:Functional MTI Functional MTI miRTarbase 1.79E-04 9.68E-01 3.02E-04 2.77E-03 12 262 "F3,WAC,ATM,SON,ADAM15,GNAS,CRB1,DAAM2,PCDH9,ZMYND8,RBPJ,TOMM20" MicroRNA hsa-miR-4708-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.80E-04 9.75E-01 3.03E-04 2.78E-03 6 64 "ARID1A,TACC2,RBPJ,PUM1,PSD,DNM2" MicroRNA "AAGTCCA,MIR-422A:MSigDB" "AAGTCCA,MIR-422A:MSigDB" MSigDB 1.80E-04 9.75E-01 3.03E-04 2.78E-03 6 64 "FOXG1,SOX6,NSD2,CALN1,DSCAM,EN2" MicroRNA "AAGTCCA,MIR-422B:MSigDB" "AAGTCCA,MIR-422B:MSigDB" MSigDB 1.80E-04 9.75E-01 3.03E-04 2.78E-03 6 64 "FOXG1,SOX6,NSD2,CALN1,DSCAM,EN2" MicroRNA hsa-miR-4687-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.80E-04 9.75E-01 3.03E-04 2.78E-03 6 64 "ZCCHC24,ADGRB2,AJAP1,DDR2,TPM3,KCNH1" MicroRNA "ACAACCT,MIR-453:MSigDB" "ACAACCT,MIR-453:MSigDB" MSigDB 1.80E-04 9.77E-01 3.04E-04 2.79E-03 5 41 "ITSN1,PKNOX2,PCDH8,SNX27,FAM135B" MicroRNA hsa-miR-140-3p:Functional MTI Functional MTI miRTarbase 1.81E-04 9.78E-01 3.04E-04 2.79E-03 11 224 "CLIP1,DRAXIN,MOBP,SLC2A5,NFASC,NUDT21,CADM1,UBTF,MAPK8,RPRD1A,EPB41" MicroRNA hsa-miR-4525:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-04 9.85E-01 3.06E-04 2.81E-03 9 153 "ANK1,PKNOX2,RAP1GAP2,CAMK2A,DLGAP3,UBTF,SPATA6,PTPA,EFNA3" MicroRNA hsa-miR-3136-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-04 9.97E-01 3.10E-04 2.84E-03 7 91 "FGF1,SMOC1,DDR2,DAAM2,ST8SIA5,FEZ2,CADM2" MicroRNA hsa-miR-664a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-04 9.97E-01 3.10E-04 2.84E-03 7 91 "MEG3,ARID1A,ADCYAP1R1,GPR26,MAPK8,NAV2,EN2" MicroRNA hsa-miR-4439:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-04 9.97E-01 3.10E-04 2.84E-03 7 91 "FGF1,SMOC1,DDR2,DAAM2,ST8SIA5,FEZ2,CADM2" MicroRNA hsa-miR-3606-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.85E-04 1.00E+00 3.11E-04 2.85E-03 10 188 "SGIP1,ASCL1,TCF7L2,PSD3,NEGR1,CCSER2,SF1,PRKACB,CADM2,JMJD1C" MicroRNA "GGCACTT,MIR-519E:MSigDB" "GGCACTT,MIR-519E:MSigDB" MSigDB 1.86E-04 1.00E+00 3.13E-04 2.87E-03 8 121 "WAC,YPEL4,SON,OPCML,ZFP91,DPYSL5,PTPRD,RAB5B" MicroRNA hsa-miR-5010-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-04 1.00E+00 3.21E-04 2.95E-03 9 154 "ANK1,PKNOX2,RAP1GAP2,CAMK2A,DLGAP3,UBTF,SPATA6,PTPA,EFNA3" MicroRNA "GTTAAAG,MIR-302B:MSigDB" "GTTAAAG,MIR-302B:MSigDB" MSigDB 1.96E-04 1.00E+00 3.30E-04 3.02E-03 6 65 "ANK2,PCDH9,PRRX1,POU3F2,CTNND2,KCNMA1" MicroRNA hsa-miR-1288:PITA hsa-miR-1288:PITA_TOP PITA 1.96E-04 1.00E+00 3.30E-04 3.02E-03 6 65 "NMNAT2,NEUROD1,ANO4,CAMK2G,GRIK2,PROX1" MicroRNA hsa-miR-1281:mirSVR_highEffct hsa-miR-1281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-04 1.00E+00 3.31E-04 3.03E-03 7 92 "ST3GAL3,MSRA,VSTM2A,TMEM25,AIFM1,PTPRD,KCNK2" MicroRNA hsa-miR-6786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-04 1.00E+00 3.37E-04 3.09E-03 4 23 "LRRC55,GNAS,MICAL2,ABI2" MicroRNA hsa-miR-30e-5p:Functional MTI Functional MTI miRTarbase 2.02E-04 1.00E+00 3.38E-04 3.10E-03 14 347 "CDC7,CHST15,SEMA6A,FOXG1,MIER1,MTR,ATM,EML4,ZMYND8,PPP3CB,MAPK8,SEC61A2,RNF220,EPB41" MicroRNA hsa-miR-873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-04 1.00E+00 3.45E-04 3.16E-03 12 266 "ADAR,KIAA1109,TACC2,SLC2A5,GJB1,CAMSAP2,DDR1,GPR37L1,VAV2,CTNND1,BLOC1S6,EN2" MicroRNA hsa-miR-6869-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-04 1.00E+00 3.49E-04 3.20E-03 8 123 "SRARP,SGIP1,SESN3,PALLD,RNF14,KIAA0513,RAB5B,RPRD1A" MicroRNA hsa-miR-1252-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-04 1.00E+00 3.53E-04 3.24E-03 9 156 "MRVI1,MDM4,MYBPC1,SALL3,GNAS,NUDT21,CCSER2,OSBPL3,CSDE1" MicroRNA hsa-miR-505-3p.2:TargetScan hsa-miR-505-3p.2 TargetScan 2.13E-04 1.00E+00 3.56E-04 3.27E-03 12 267 "ADORA3,GAS7,NSG2,NRG3,ATP2B2,ARPP21,PTPN5,CDC42,KIAA0408,OCIAD1,KCNN3,OLIG2" MicroRNA hsa-miR-8059:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-04 1.00E+00 3.58E-04 3.28E-03 6 66 "SCN4B,TACC2,NFASC,PHKG1,PRKAB2,ABI2" MicroRNA hsa-miR-4471:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-04 1.00E+00 3.58E-04 3.28E-03 6 66 "SCN4B,TACC2,NFASC,PHKG1,PRKAB2,ABI2" MicroRNA hsa-miR-9-5p:Functional MTI Functional MTI miRTarbase 2.20E-04 1.00E+00 3.68E-04 3.38E-03 14 350 "TTYH1,MDM4,TESK2,SLC2A5,MSR1,NMNAT2,EMC1,KIF1B,NKX2-2,RBFOX2,PLEKHB1,PRRX1,ATL1,EN2" MicroRNA hsa-miR-7158-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-04 1.00E+00 3.70E-04 3.39E-03 9 157 "CACNB2,BEST3,SLC36A4,ATCAY,PNKD,PRKACB,KCNN3,GNE,SEC61A2" MicroRNA hsa-miR-8081:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 3.76E-04 3.45E-03 7 94 "SRARP,DNAH17,ERBIN,FAM168A,CYB561A3,PLD5,JMJD1C" MicroRNA hsa-miR-4436b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 3.76E-04 3.45E-03 7 94 "GRAMD1B,SESN3,HPR,VCAN,NOS1AP,CALN1,RCAN2" MicroRNA hsa-miR-431:PITA hsa-miR-431:PITA_TOP PITA 2.25E-04 1.00E+00 3.76E-04 3.45E-03 7 94 "API5,SON,CAMTA1,ZFP91,C1orf94,SMG7,PTPRZ1" MicroRNA hsa-miR-432-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-04 1.00E+00 3.76E-04 3.45E-03 7 94 "ADAR,C10orf105,ATM,GNAS,RBFOX2,ANO5,CSDE1" MicroRNA "GCAAGAC,MIR-431:MSigDB" "GCAAGAC,MIR-431:MSigDB" MSigDB 2.27E-04 1.00E+00 3.79E-04 3.47E-03 5 43 "CAMTA1,TBX15,BTF3L4,CEP170,EPB41L1" MicroRNA hsa-miR-4533:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-04 1.00E+00 3.79E-04 3.47E-03 11 230 "ZFYVE27,ARID1A,DRAXIN,WDTC1,TTLL9,TMEM9,TPM3,PACSIN1,FAM131B,PHC2,EN2" MicroRNA hsa-miR-4659a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-04 1.00E+00 3.79E-04 3.47E-03 11 230 "ASCL1,TMEM151A,ACSL6,GRIK3,TNS1,CDH8,FNDC5,NEGR1,TENM4,SH3GLB1,ABI2" MicroRNA hsa-miR-4659b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-04 1.00E+00 3.79E-04 3.47E-03 11 230 "ASCL1,TMEM151A,ACSL6,GRIK3,TNS1,CDH8,FNDC5,NEGR1,TENM4,SH3GLB1,ABI2" MicroRNA hsa-miR-1343-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-04 1.00E+00 3.81E-04 3.50E-03 10 193 "CLSTN1,ASPH,LHFPL4,NFASC,FAM168A,DIRAS1,UBTF,PTPA,RGS6,PHYHIP" MicroRNA hsa-miR-2276-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-04 1.00E+00 3.86E-04 3.54E-03 9 158 "MAPT,BCAN,WWC1,ACSL6,SCRG1,DLGAP3,RNF14,PTAFR,UEVLD" MicroRNA hsa-miR-887:PITA hsa-miR-887:PITA_TOP PITA 2.38E-04 1.00E+00 3.97E-04 3.64E-03 4 24 "ADD3,ASTN1,ATP2B2,MAGI2" MicroRNA hsa-miR-523:mirSVR_highEffct hsa-miR-523:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-04 1.00E+00 3.97E-04 3.64E-03 4 24 "URGCP,TJP1,SF1,CTNND2" MicroRNA hsa-miR-8084:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-04 1.00E+00 4.01E-04 3.68E-03 7 95 "MYBPC1,SALL3,CAMSAP2,NUDT21,PSD3,HMGB1,ABI2" MicroRNA hsa-miR-3653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-04 1.00E+00 4.02E-04 3.69E-03 20 627 "SLC7A14,KIAA1614,ATM,TMEM151A,BCL2L2,CNDP1,CACNB2,P2RX7,HMGB1,MEAF6,ATCAY,RIMS4,KIAA0408,ZBTB16,RABGAP1L,KCNN3,WIPF2,SSPN,PLEKHO1,UEVLD" MicroRNA hsa-miR-2467-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.44E-04 1.00E+00 4.06E-04 3.73E-03 16 441 "PLEKHG5,MAGI3,CCDC80,KIAA1614,ATM,SCN3B,SON,ACSBG1,GNG4,NUCB1,PADI2,TPM3,SCRG1,RBPJ,KCNH1,SNX27" MicroRNA hsa-miR-5695:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.46E-04 1.00E+00 4.09E-04 3.75E-03 8 126 "F3,CAB39,NFASC,CACNA1A,PTGDR2,PDE1A,FGFR1OP2,ZNF248" MicroRNA hsa-miR-493-3p:TargetScan hsa-miR-493-3p TargetScan 2.46E-04 1.00E+00 4.09E-04 3.75E-03 8 126 "EPS8,MRVI1,NFASC,KCNK10,COL9A2,JAKMIP2,KCNJ9,DLG3" MicroRNA hsa-miR-3591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 4.19E-04 3.84E-03 6 68 "GPAM,SON,CDC42,SF1,ELMO1,SH3GLB1" MicroRNA hsa-miR-4467:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 4.19E-04 3.84E-03 6 68 "DNAH17,WSCD1,BRSK2,FBXL16,GPR37L1,NSD2" MicroRNA hsa-miR-4666b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-04 1.00E+00 4.19E-04 3.84E-03 6 68 "NLGN4X,SLC7A14,TNR,PCSK2,VCAN,UEVLD" MicroRNA hsa-miR-191-5p:TargetScan hsa-miR-191-5p TargetScan 2.53E-04 1.00E+00 4.21E-04 3.86E-03 5 44 "ATP2B2,AJAP1,NFIA,CALN1,PHC2" MicroRNA hsa-miR-6795-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-04 1.00E+00 4.26E-04 3.91E-03 7 96 "ACTN2,SMARCE1,ATP1A2,TMEM151B,PADI2,PNKD,KCNJ10" MicroRNA hsa-miR-3160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.69E-04 1.00E+00 4.48E-04 4.11E-03 10 197 "TUBB4A,SMARCE1,ACSBG1,TMEM136,CECR2,TPM4,ADGRG1,FAT3,NOS1AP,HP1BP3" MicroRNA hsa-miR-4679:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-04 1.00E+00 4.53E-04 4.15E-03 6 69 "APC2,MDM4,TOMM40L,SMOC1,SDC3,TTLL7" MicroRNA hsa-miR-219a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-04 1.00E+00 4.53E-04 4.15E-03 6 69 "SESN3,HMGB1,PLD5,CTNND1,PMEPA1,NKAIN1" MicroRNA hsa-miR-432-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-04 1.00E+00 4.53E-04 4.15E-03 6 69 "PCDH11X,GNAS,RBFOX2,C1orf109,NKAIN1,ABI2" MicroRNA hsa-miR-342-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-04 1.00E+00 4.53E-04 4.16E-03 8 128 "MDM4,FOXRED2,NMNAT2,UBTF,SPATA6,MICAL2,MAPK10,VANGL2" MicroRNA hsa-miR-4328:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-04 1.00E+00 4.53E-04 4.16E-03 8 128 "CCDC80,GPAM,NMNAT2,UNC5D,PCSK2,ZFYVE9,MEAF6,ELAVL3" MicroRNA hsa-miR-718:mirSVR_lowEffct hsa-miR-718:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.79E-04 1.00E+00 4.62E-04 4.24E-03 13 316 "ATAT1,LHFPL4,ZNF638,CDK5R2,LINC00839,FBXL16,UBTF,MED1,LRP8,DNM2,ZYG11B,RET,EPB41L1" MicroRNA "AGCATTA,MIR-155:MSigDB" "AGCATTA,MIR-155:MSigDB" MSigDB 2.88E-04 1.00E+00 4.78E-04 4.38E-03 8 129 "SOX1,CAB39,CAMTA1,GPM6B,PCDH9,WBP1L,TOMM20,KCNN3" MicroRNA hsa-miR-34a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.91E-04 1.00E+00 4.83E-04 4.43E-03 22 735 "MDM4,ANK3,DGKZ,SON,NASP,GANAB,CAMTA1,ACSL6,AIFM1,ATG4C,TPD52,MAGI1,HMGB1,TJP2,BTF3L4,CEP170,KCNH1,KIF2A,RTN4,L1CAM,RBM12,EPB41L2" MicroRNA hsa-miR-939-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.92E-04 1.00E+00 4.84E-04 4.44E-03 10 199 "CLSTN1,ASPH,LHFPL4,NFASC,FAM168A,DIRAS1,UBTF,PTPA,RGS6,PHYHIP" MicroRNA hsa-miR-6134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.92E-04 1.00E+00 4.85E-04 4.45E-03 14 360 "ARID1A,FXYD6,PTBP2,FTO,FAT3,ACBD5,KIAA0513,HP1BP3,WIPF2,RAB5B,PLEKHB2,PARP11,SSPN,ABI2" MicroRNA hsa-miR-4714-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 4.89E-04 4.48E-03 6 70 "ADCY2,MOG,TACC2,ACSL6,CAMKV,ZYG11B" MicroRNA hsa-miR-1251:mirSVR_highEffct hsa-miR-1251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.03E-04 1.00E+00 5.02E-04 4.60E-03 15 405 "DUSP27,GRAMD1B,GPR158,PCDH11X,KAZN,WWC1,VXN,CYB561A3,TMEM257,TPD52,CASC2,KCNA2,C1orf109,KCNK2,HS3ST4" MicroRNA hsa-miR-4676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-04 1.00E+00 5.02E-04 4.61E-03 8 130 "KCNIP2,API5,AKNA,NEURL1,RBFOX2,MEAF6,FAT3,UEVLD" MicroRNA "ACTACCT,MIR-196A:MSigDB" "ACTACCT,MIR-196A:MSigDB" MSigDB 3.04E-04 1.00E+00 5.02E-04 4.61E-03 8 130 "SYT9,GAS7,AQP4,SLC8A2,ACSL6,OPCML,ZNF385B,BLOC1S6" MicroRNA hsa-miR-575:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-04 1.00E+00 5.02E-04 4.61E-03 8 130 "KCNIP2,API5,AKNA,NEURL1,RBFOX2,MEAF6,FAT3,UEVLD" MicroRNA "ACTACCT,MIR-196B:MSigDB" "ACTACCT,MIR-196B:MSigDB" MSigDB 3.04E-04 1.00E+00 5.02E-04 4.61E-03 8 130 "SYT9,GAS7,AQP4,SLC8A2,ACSL6,OPCML,ZNF385B,BLOC1S6" MicroRNA hsa-miR-145-5p:Functional MTI Functional MTI miRTarbase 3.04E-04 1.00E+00 5.02E-04 4.61E-03 11 238 "RTKN,NDRG2,ADD3,CCDC80,MYRF,UNC5D,TNR,TPM3,ZFYVE9,CTNND1,PRDM2" MicroRNA hsa-miR-425:PITA hsa-miR-425:PITA_TOP PITA 3.04E-04 1.00E+00 5.02E-04 4.61E-03 10 200 "AMPH,ANK3,SNAP25,DKK3,CAB39,CPLX2,NMT2,CTNND1,PTCH1,FAM135B" MicroRNA hsa-miR-3127-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-04 1.00E+00 5.04E-04 4.62E-03 9 164 "CDHR1,WAC,SHANK2,NASP,DCAF5,TENM4,FGFR1OP2,PMEPA1,CALN1" MicroRNA hsa-let-7a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-04 1.00E+00 5.08E-04 4.66E-03 20 639 "MDM4,CDC7,TUBB4A,TOMM40L,JPH4,SALL3,GPM6B,TGFBR3,ATG4C,RBFOX2,VAV2,POU3F2,DNAJC6,SMG7,DNAH9,C12orf4,FAM13C,BSDC1,RAVER2,PLEKHO1" MicroRNA hsa-miR-617:PITA hsa-miR-617:PITA_TOP PITA 3.10E-04 1.00E+00 5.11E-04 4.69E-03 7 99 "SORBS1,SOX1,UNC5D,FBXL16,ZFP91,PAK5,ARHGAP12" MicroRNA hsa-miR-604:mirSVR_highEffct hsa-miR-604:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.10E-04 1.00E+00 5.11E-04 4.69E-03 7 99 "ATAT1,ALDH4A1,SEPT3,ARHGEF7,NTSR2,MED1,PNKD" MicroRNA hsa-miR-5685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-04 1.00E+00 5.11E-04 4.69E-03 7 99 "ALDH4A1,IGSF9B,NEURL1,TPM3,PDE2A,PIK3CD,ZBTB16" MicroRNA hsa-miR-3920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-04 1.00E+00 5.16E-04 4.74E-03 5 46 "ZCCHC24,PPP3CB,PUM1,KCNN3,SH3GLB1" MicroRNA hsa-miR-4419b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-04 1.00E+00 5.16E-04 4.74E-03 17 497 "SLC2A5,ATM,WDTC1,VAMP1,ZNF638,PTBP2,AKNA,PAX6,TPM3,MFSD4A,PLD5,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-124-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.19E-04 1.00E+00 5.25E-04 4.82E-03 6 71 "ACHE,FOXG1,RPH3A,ASTN2,SDC3,EN2" MicroRNA hsa-miR-892b:Functional MTI Functional MTI miRTarbase 3.19E-04 1.00E+00 5.25E-04 4.82E-03 6 71 "CACNA1E,TCF7L2,ZNF384,MAPK8,RGMA,ABI2" MicroRNA hsa-miR-298:Functional MTI Functional MTI miRTarbase 3.19E-04 1.00E+00 5.26E-04 4.82E-03 9 165 "MIER1,SLC8A3,WDTC1,HAP1,TMPRSS5,UBTF,CCSER2,CSDE1,PLEKHB2" MicroRNA hsa-miR-488-3p:Functional MTI Functional MTI miRTarbase 3.20E-04 1.00E+00 5.26E-04 4.83E-03 8 131 "ARID1A,SGIP1,NAXD,ERBIN,GPR26,PAX6,TPM3,PRDM2" MicroRNA hsa-miR-1324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.20E-04 1.00E+00 5.26E-04 4.83E-03 8 131 "SDE2,ADAR,NLGN4X,TACC2,SLC1A2,NBPF1,SLIT1,P2RX7" MicroRNA hsa-miR-130a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.20E-04 1.00E+00 5.26E-04 4.83E-03 8 131 "ADD3,NLGN4X,ERBIN,TPM3,CRLS1,BSDC1,JMJD1C,EN2" MicroRNA hsa-miR-4478:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.20E-04 1.00E+00 5.27E-04 4.83E-03 17 498 "SLC2A5,ATM,WDTC1,VAMP1,ZNF638,PTBP2,AKNA,PAX6,TPM3,MFSD4A,PLD5,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-3929:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.20E-04 1.00E+00 5.27E-04 4.83E-03 17 498 "SLC2A5,ATM,WDTC1,VAMP1,ZNF638,PTBP2,AKNA,PAX6,TPM3,MFSD4A,PLD5,KIAA0513,SNX27,DNAH9,PLEKHB2,GNE,SYT15" MicroRNA hsa-miR-3131:mirSVR_highEffct hsa-miR-3131:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.29E-04 1.00E+00 5.41E-04 4.97E-03 7 100 "SEMA6C,DACH2,C11orf87,SMOC1,VAMP1,NLGN3,SHD" MicroRNA hsa-miR-4690-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.29E-04 1.00E+00 5.41E-04 4.97E-03 7 100 "ALDH4A1,IGSF9B,NEURL1,TPM3,PDE2A,PIK3CD,ZBTB16" MicroRNA hsa-miR-5683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.29E-04 1.00E+00 5.41E-04 4.97E-03 7 100 "EML4,PDE3B,MEAF6,DOCK7,BLOC1S6,KCNN3,RGR" MicroRNA hsa-miR-450a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.29E-04 1.00E+00 5.41E-04 4.97E-03 7 100 "MDM4,DRAXIN,NMNAT2,FAM168A,CACNB2,MEAF6,MAPK10" MicroRNA hsa-miR-3185:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.33E-04 1.00E+00 5.48E-04 5.02E-03 9 166 "MOG,ARHGEF7,PFKFB3,NEGR1,PACSIN1,SF1,VCAN,CTNND1,RIMS3" MicroRNA hsa-miR-6829-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 5.48E-04 5.02E-03 13 322 "TESK2,MOG,PKNOX2,TMEM151A,AJAP1,NKX2-2,CNDP1,CACNA1A,HMGB1,KIAA0408,PTAFR,RABGAP1L,TMCC2" MicroRNA hsa-miR-6791-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 5.48E-04 5.02E-03 13 322 "TESK2,MOG,PKNOX2,TMEM151A,AJAP1,NKX2-2,CNDP1,CACNA1A,HMGB1,KIAA0408,PTAFR,RABGAP1L,TMCC2" MicroRNA hsa-miR-25*:mirSVR_highEffct hsa-miR-25*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.36E-04 1.00E+00 5.52E-04 5.06E-03 8 132 "FAM168A,ACSBG1,SEZ6L,ANKS1B,PRTFDC1,BSDC1,CBLN2,UEVLD" MicroRNA hsa-miR-23c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-04 1.00E+00 5.52E-04 5.06E-03 8 132 "ADD3,NLGN4X,ERBIN,TPM3,CRLS1,BSDC1,JMJD1C,EN2" MicroRNA hsa-miR-1233-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-04 1.00E+00 5.52E-04 5.06E-03 8 132 "SCN4B,ZCCHC24,GPR37L1,FTO,RGS6,TOMM20,KCNH1,KCNJ11" MicroRNA hsa-miR-4483:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-04 1.00E+00 5.52E-04 5.06E-03 8 132 "MAGI3,NUCB1,TPM3,UBTF,PACSIN1,SIRPA,RAB5B,ABI2" MicroRNA hsa-miR-4281:mirSVR_lowEffct hsa-miR-4281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.45E-04 1.00E+00 5.65E-04 5.18E-03 15 410 "PNMA8B,LRRC7,STK32C,BCL2L2,GNG3,GPM6A,PTBP2,CECR2,GRIA1,HPSE2,VAV2,STMN4,RALGDS,CBLN2,SEZ6" MicroRNA "CAGTCAC,MIR-134:MSigDB" "CAGTCAC,MIR-134:MSigDB" MSigDB 3.46E-04 1.00E+00 5.67E-04 5.21E-03 5 47 "ASIC1,ILDR2,ADGRL3,PSD3,OPCML" MicroRNA hsa-miR-663:PITA hsa-miR-663:PITA_TOP PITA 3.46E-04 1.00E+00 5.67E-04 5.21E-03 5 47 "DPF1,MAPT,CSMD2,SLITRK1,NCDN" MicroRNA hsa-miR-644:PITA hsa-miR-644:PITA_TOP PITA 3.50E-04 1.00E+00 5.73E-04 5.26E-03 7 101 "NLGN4X,TMEM151A,BCL2L2,GPR88,MICAL2,DLG2,EPB41L2" MicroRNA hsa-miR-548e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.55E-04 1.00E+00 5.82E-04 5.34E-03 10 204 "ADORA3,SESN3,SON,FAM168A,GPM6A,RBFOX2,PACSIN1,OSBPL3,PUM1,TTLL7" MicroRNA hsa-miR-4289:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-04 1.00E+00 6.06E-04 5.56E-03 6 73 "SEMA6A,SON,GFRA1,PAX6,DLGAP3,MEAF6" MicroRNA hsa-miR-7109-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-04 1.00E+00 6.06E-04 5.56E-03 6 73 "FGF1,TMEM151B,PKN2,WIPF2,CBLN2,UEVLD" MicroRNA hsa-miR-8070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.71E-04 1.00E+00 6.06E-04 5.56E-03 6 73 "CLIP1,TOMM40L,ATM,SON,CD81,PROX1" MicroRNA hsa-miR-1470:mirSVR_highEffct hsa-miR-1470:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.71E-04 1.00E+00 6.06E-04 5.56E-03 6 73 "LOC100128239,NTNG1,DDR1,DLG2,DPP6,GPR61" MicroRNA hsa-miR-3616-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-04 1.00E+00 6.08E-04 5.58E-03 7 102 "CHST15,SESN3,SLC6A9,TMPRSS5,PHYHIP,PMEPA1,ARHGAP12" MicroRNA hsa-miR-505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-04 1.00E+00 6.08E-04 5.58E-03 8 134 "APC2,NSG2,CAMK2A,TMEM9,ZFP91,PTPA,PLD5,ATN1" MicroRNA "TTCCGTT,MIR-191:MSigDB" "TTCCGTT,MIR-191:MSigDB" MSigDB 3.81E-04 1.00E+00 6.23E-04 5.72E-03 4 27 "ATP2B2,ZCCHC24,TJP1,PHC2" MicroRNA hsa-miR-202-3p:Functional MTI Functional MTI miRTarbase 3.84E-04 1.00E+00 6.27E-04 5.75E-03 10 206 "SDE2,MDM4,TOMM40L,SOX6,ANK1,SALL3,TGFBR3,RBFOX2,ARHGAP22,PLEKHO1" MicroRNA hsa-miR-4701-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-04 1.00E+00 6.34E-04 5.81E-03 11 245 "GOLGA7B,SLC7A14,ATP1A2,KIF21B,KIF1B,WWC1,ATCAY,FGFR1OP2,BLOC1S6,RABGAP1L,SIDT2" MicroRNA hsa-miR-1293:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-04 1.00E+00 6.39E-04 5.86E-03 8 135 "MAGI3,NUCB1,TPM3,UBTF,PACSIN1,SIRPA,RAB5B,ABI2" MicroRNA hsa-miR-6777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-04 1.00E+00 6.43E-04 5.90E-03 7 103 "BCL2L2,HPR,VCAN,SPIRE1,SIRPA,PMEPA1,RCAN2" MicroRNA hsa-miR-6792-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-04 1.00E+00 6.43E-04 5.90E-03 7 103 "SESN3,MYT1L,TPD52,NEGR1,SLC25A27,C12orf4,EN2" MicroRNA "GGTGTGT,MIR-329:MSigDB" "GGTGTGT,MIR-329:MSigDB" MSigDB 3.94E-04 1.00E+00 6.43E-04 5.90E-03 7 103 "RXRG,CLSTN1,NFASC,PTBP2,CRMP1,PRKACB,SRGAP3" MicroRNA hsa-miR-509-3p:PITA hsa-miR-509-3p:PITA_TOP PITA 3.94E-04 1.00E+00 6.43E-04 5.90E-03 7 103 "WLS,GPR158,SFPQ,AHCYL1,CAMK2A,PPP2R5C,KCNMA1" MicroRNA hsa-miR-920:PITA hsa-miR-920:PITA_TOP PITA 3.94E-04 1.00E+00 6.43E-04 5.90E-03 7 103 "ASIC1,BCL2L2,CACNA1A,NUMA1,ZNF384,NLGN3,MED1" MicroRNA hsa-miR-373-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.95E-04 1.00E+00 6.43E-04 5.90E-03 14 371 "KIF1B,TMEM136,TCF7L2,RFFL,VWCE,OLR1,PTGDR2,GPR37L1,CCSER2,MAPK8,RABGAP1L,WIPF2,ARHGAP12,ELAVL4" MicroRNA hsa-miR-4756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.96E-04 1.00E+00 6.45E-04 5.92E-03 12 286 "MAG,RTKN,CLSTN1,RPH3A,GNG3,DDR1,TPM3,TMPRSS5,PTPA,RGS6,NAV2,PARP11" MicroRNA hsa-miR-125b-1*:mirSVR_highEffct hsa-miR-125b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-04 1.00E+00 6.50E-04 5.96E-03 6 74 "NDRG2,BCAS1,RPH3A,DNER,PIRT,CNTN1" MicroRNA hsa-miR-4435:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-04 1.00E+00 6.54E-04 6.00E-03 11 246 "GOLGA7B,ATP1A2,KIF1B,WWC1,TCF7L2,ZNF384,ATCAY,KIAA0513,BLOC1S6,RABGAP1L,SIDT2" MicroRNA hsa-miR-371b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-04 1.00E+00 6.60E-04 6.05E-03 14 372 "KIF1B,TMEM136,TCF7L2,RFFL,VWCE,OLR1,PTGDR2,GPR37L1,CCSER2,MAPK8,RABGAP1L,WIPF2,ARHGAP12,ELAVL4" MicroRNA hsa-miR-5089-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.06E-04 1.00E+00 6.60E-04 6.05E-03 14 372 "FOXRED2,LRRC55,EMC1,BCL2L2,WWC1,GRIK2,MFSD2A,HMGB1,ATCAY,OCIAD1,KCND3,RABGAP1L,ABI2,EPB41L1" MicroRNA hsa-miR-1321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.08E-04 1.00E+00 6.64E-04 6.09E-03 12 287 "MAG,RTKN,CLSTN1,RPH3A,GNG3,DDR1,TPM3,TMPRSS5,PTPA,RGS6,NAV2,PARP11" MicroRNA hsa-miR-362-5p:PITA hsa-miR-362-5p:PITA_TOP PITA 4.11E-04 1.00E+00 6.69E-04 6.13E-03 8 136 "MRVI1,LRRTM4,GPR88,RIMS4,PRKACB,SYNC,PTPRD,PTPRE" MicroRNA hsa-miR-598:PITA hsa-miR-598:PITA_TOP PITA 4.22E-04 1.00E+00 6.85E-04 6.29E-03 5 49 "ARID1A,B3GALT2,ZFP91,CHD5,PTPRZ1" MicroRNA hsa-miR-453:PITA hsa-miR-453:PITA_TOP PITA 4.29E-04 1.00E+00 6.97E-04 6.39E-03 6 75 "SOX6,NPAS3,TCF12,PTBP2,FMN2,DLG2" MicroRNA hsa-miR-92b*:mirSVR_highEffct hsa-miR-92b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.29E-04 1.00E+00 6.97E-04 6.39E-03 6 75 "ACHE,NTNG1,SMARCE1,B4GALNT1,PRMT8,POU3F2" MicroRNA hsa-miR-2114-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.29E-04 1.00E+00 6.97E-04 6.39E-03 6 75 "FABP7,PKNOX2,NEGR1,PLD5,TMCC2,FAM135B" MicroRNA hsa-miR-5582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-04 1.00E+00 6.98E-04 6.40E-03 11 248 "SORCS1,SMOC1,NUDT21,DDR2,GRIK4,TJP1,RIMS4,PKN2,KLRC3,ZYG11B,ABI2" MicroRNA hsa-miR-455-5p:PITA hsa-miR-455-5p:PITA_TOP PITA 4.32E-04 1.00E+00 7.00E-04 6.43E-03 8 137 "ADD3,CAB39,DCAF5,TJP1,NXPH1,CTNND1,ATG16L1,ARHGAP12" MicroRNA hsa-miR-216b-5p:Functional MTI Functional MTI miRTarbase 4.32E-04 1.00E+00 7.00E-04 6.43E-03 8 137 "PDZD4,FOXM1,CDC42BPA,P2RX7,TPM3,PRKAB2,RIMS3,NUP214" MicroRNA hsa-miR-891a:mirSVR_highEffct hsa-miR-891a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.32E-04 1.00E+00 7.00E-04 6.43E-03 8 137 "SGIP1,NSG2,MYT1L,VAMP1,FMN2,OCIAD1,RGS7,SLC4A10" MicroRNA hsa-miR-203b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-04 1.00E+00 7.01E-04 6.43E-03 9 172 "MDM4,CACNB2,RBFOX2,SLC36A4,ATCAY,PNKD,PRDM2,KCNN3,GNE" MicroRNA hsa-miR-5692a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.34E-04 1.00E+00 7.04E-04 6.46E-03 12 289 "ACER3,RTN3,ARID1A,TMEM156,SON,DDHD2,TPD52,MEAF6,PKN2,WIPF2,PLEKHB2,PLEKHO1" MicroRNA hsa-miR-1234:PITA hsa-miR-1234:PITA_TOP PITA 4.40E-04 1.00E+00 7.14E-04 6.55E-03 4 28 "SH3GL2,NCDN,LMO1,ELAVL3" MicroRNA hsa-miR-941:mirSVR_highEffct hsa-miR-941:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.43E-04 1.00E+00 7.18E-04 6.59E-03 7 105 "ITSN1,RGL1,CRB1,TMEM25,NSD2,NCAN,RGS10" MicroRNA hsa-miR-1308:PITA hsa-miR-1308:PITA_TOP PITA 4.43E-04 1.00E+00 7.18E-04 6.59E-03 7 105 "SLITRK1,ELMOD1,NLGN3,LRP8,MAGI2,TMEM255A,SLC17A6" MicroRNA hsa-miR-1233:mirSVR_highEffct hsa-miR-1233:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.45E-04 1.00E+00 7.21E-04 6.61E-03 13 332 "DUSP27,ATAT1,RTKN,SLC14A1,SOX5,GANAB,KLHL4,CRB1,TPM3,FEZ1,NAV2,DLG2,DTNA" MicroRNA hsa-miR-539-5p:Functional MTI Functional MTI miRTarbase 4.46E-04 1.00E+00 7.22E-04 6.63E-03 10 210 "SESN3,CCDC80,SFMBT2,C10orf105,CAB39,ACSL6,TCF7L2,ZEB1,SF1,OSBPL3" MicroRNA hsa-miR-25-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.46E-04 1.00E+00 7.22E-04 6.63E-03 10 210 "MDM4,KBTBD12,FBXL16,TPM3,JAM2,PIK3CD,MICAL2,PRKCZ,PHYHIP,ELAVL3" MicroRNA hsa-miR-4739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-04 1.00E+00 7.25E-04 6.65E-03 12 290 "MAG,RTKN,CLSTN1,RPH3A,GNG3,DDR1,TPM3,TMPRSS5,PTPA,RGS6,NAV2,PARP11" MicroRNA hsa-miR-6835-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-04 1.00E+00 7.33E-04 6.72E-03 8 138 "F3,CCDC80,NEUROD1,TPD52,CRLS1,KIAA0408,NAV2,EFNA3" MicroRNA hsa-miR-296-5p:TargetScan hsa-miR-296-5p TargetScan 4.53E-04 1.00E+00 7.33E-04 6.72E-03 8 138 "CADM3,DDR1,DIRAS1,PTPN5,DLGAP3,RIMS4,KCNA6,PHC2" MicroRNA hsa-miR-6878-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-04 1.00E+00 7.43E-04 6.82E-03 11 250 "SOX6,NDUFA5,AJAP1,CHRNB2,UBTF,CCSER2,FTO,BTF3L4,PTPA,PTPRE,RAB5B" MicroRNA "CTCCAAG,MIR-432:MSigDB" "CTCCAAG,MIR-432:MSigDB" MSigDB 4.61E-04 1.00E+00 7.44E-04 6.82E-03 6 76 "EML4,VXN,PSD3,GRIA2,ZFP91,NSD2" MicroRNA hsa-miR-4778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.61E-04 1.00E+00 7.44E-04 6.82E-03 6 76 "GRAMD1B,EMC1,BTF3L4,JAKMIP2,CADM2,TMEM100" MicroRNA hsa-miR-630:Functional MTI Functional MTI miRTarbase 4.61E-04 1.00E+00 7.44E-04 6.82E-03 6 76 "FOXM1,BCL2L2,GPR26,RBFOX2,JAKMIP2,PAK5" MicroRNA hsa-miR-874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.61E-04 1.00E+00 7.44E-04 6.82E-03 6 76 "ANK1,SLC8A3,TMEM151A,BCL2L2,VAMP1,VANGL2" MicroRNA hsa-miR-181c-5p:Functional MTI Functional MTI miRTarbase 4.62E-04 1.00E+00 7.45E-04 6.84E-03 12 291 "EPS8,SLC25A25,NDRG2,CAPRIN2,ATM,TUB,NMT2,NSD2,PNKD,OSBPL3,SPIRE1,EN2" MicroRNA hsa-miR-1292-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-04 1.00E+00 7.47E-04 6.86E-03 5 50 "NFASC,NRGN,PHKG1,PRKAB2,ABI2" MicroRNA hsa-miR-3141:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-04 1.00E+00 7.47E-04 6.86E-03 5 50 "JAKMIP3,NRGN,BRSK2,FBXL16,ELAVL3" MicroRNA "GTCAGGA,MIR-378:MSigDB" "GTCAGGA,MIR-378:MSigDB" MSigDB 4.63E-04 1.00E+00 7.47E-04 6.86E-03 5 50 "CCDC88A,ATP2B2,CRB1,NSD2,VANGL2" MicroRNA hsa-miR-1224-3p:PITA hsa-miR-1224-3p:PITA_TOP PITA 4.69E-04 1.00E+00 7.57E-04 6.94E-03 7 106 "CDC42BPA,VAMP1,CAMTA1,PTBP2,STMN4,WIPF2,SLC17A6" MicroRNA hsa-miR-30e-3p:Functional MTI Functional MTI miRTarbase 4.70E-04 1.00E+00 7.57E-04 6.95E-03 9 174 "MDM4,CLSTN1,SLC1A2,NBPF1,CACNA1E,NUCB1,PCSK2,SERPINE2,KCNN3" MicroRNA hsa-miR-503-5p:Functional MTI Functional MTI miRTarbase 4.75E-04 1.00E+00 7.66E-04 7.02E-03 11 251 "ANK3,DNAH17,DDHD2,HNRNPK,DLGAP3,ANLN,PPP2R5C,TOMM20,PTPRD,RTN4,TMEM100" MicroRNA hsa-miR-5003-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-04 1.00E+00 7.66E-04 7.02E-03 8 139 "NLGN4X,USP28,LRRC55,NEUROD1,NUDT21,VCAN,KCNN3,L1CAM" MicroRNA hsa-miR-4262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-04 1.00E+00 7.66E-04 7.02E-03 8 139 "EPS8,SLC25A25,CAPRIN2,ATM,NSD2,PNKD,SPIRE1,EN2" MicroRNA hsa-miR-4282:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.91E-04 1.00E+00 7.90E-04 7.25E-03 12 293 "SDE2,MAGI3,SFMBT2,SON,TPD52,TPM3,FEZ2,ATRNL1,FMN2,MAPK8,ZYG11B,UEVLD" MicroRNA hsa-miR-379:PITA hsa-miR-379:PITA_TOP PITA 4.94E-04 1.00E+00 7.95E-04 7.29E-03 6 77 "CCDC88A,ADGRL3,MAGI1,SYNC,KCNK2,RET" MicroRNA hsa-miR-6769a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.94E-04 1.00E+00 7.95E-04 7.29E-03 6 77 "SLC8A3,BCL2L2,OPALIN,PPP3CB,DPYSL5,SIRPA" MicroRNA hsa-miR-4666a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.97E-04 1.00E+00 7.99E-04 7.33E-03 7 107 "ARID1A,RUFY2,SON,FAM69C,TNS1,OCIAD1,RCAN2" MicroRNA hsa-miR-7977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.98E-04 1.00E+00 8.00E-04 7.34E-03 20 664 "RTKN,CLSTN1,SLC1A2,SLC2A5,GNG4,AKNA,CYB561A3,OLR1,REPS2,TPM3,ZFYVE9,NEGR1,FTO,FAT3,DOCK7,NOS1AP,SNX27,WIPF2,RAB5B,FGFBP3" MicroRNA hsa-miR-193a-5p:TargetScan hsa-miR-193a-5p TargetScan 5.10E-04 1.00E+00 8.20E-04 7.53E-03 9 176 "DSCAML1,GRAMD1B,FGF14,ITSN1,GANAB,CNTN2,GRIK3,PROX1,KCNH1" MicroRNA hsa-miR-379-3p:TargetScan hsa-miR-379-3p TargetScan 5.17E-04 1.00E+00 8.30E-04 7.62E-03 10 214 "NLGN1,PHYHIPL,JPH4,CACNA1E,OPCML,KCNK10,CADM1,PTPRD,KCNN3,JMJD1C" MicroRNA hsa-miR-411-3p:TargetScan hsa-miR-411-3p TargetScan 5.17E-04 1.00E+00 8.30E-04 7.62E-03 10 214 "NLGN1,PHYHIPL,JPH4,CACNA1E,OPCML,KCNK10,CADM1,PTPRD,KCNN3,JMJD1C" MicroRNA hsa-miR-3943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-04 1.00E+00 8.50E-04 7.80E-03 6 78 "NSG2,BCL2L2,NODAL,NEURL1,SIRPA,PIANP" MicroRNA hsa-miR-4716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-04 1.00E+00 8.54E-04 7.83E-03 9 177 "SRARP,ATP1A2,KIF1B,BTF3L4,KIAA0408,FGFR1OP2,PTAFR,GNE,UEVLD" MicroRNA hsa-miR-4698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.56E-04 1.00E+00 8.92E-04 8.18E-03 10 216 "KIAA1614,TCF7L2,NUDT21,OLR1,PDE1A,DLGAP3,CCSER2,BTF3L4,TENM4,GNE" MicroRNA hsa-miR-4684-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.57E-04 1.00E+00 8.93E-04 8.19E-03 5 52 "RTN3,SLC7A14,TPM4,ZFYVE9,RAVER2" MicroRNA hsa-miR-1245b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.67E-04 1.00E+00 9.09E-04 8.34E-03 6 79 "SESN3,NUCB1,MEAF6,DOCK7,KCNN3,RGR" MicroRNA hsa-miR-611:mirSVR_highEffct hsa-miR-611:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.67E-04 1.00E+00 9.09E-04 8.34E-03 6 79 "SEMA6C,DACH2,C11orf87,VAMP1,NLGN3,SHD" MicroRNA hsa-miR-508-3p:PITA hsa-miR-508-3p:PITA_TOP PITA 5.74E-04 1.00E+00 9.20E-04 8.44E-03 8 143 "SORCS1,PHYHIPL,LMO3,CACNB2,CECR2,GRIA2,CEP170,DLG2" MicroRNA hsa-miR-5571-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.76E-04 1.00E+00 9.23E-04 8.46E-03 10 217 "SDE2,GPAM,KIAA1614,SMARCE1,ASTN2,CAMK2G,HNRNPK,SPATA6,KCNK2,L1CAM" MicroRNA hsa-miR-6500-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.76E-04 1.00E+00 9.23E-04 8.46E-03 10 217 "SERPINA3,SFMBT2,KBTBD12,AKNA,GUCY1A2,SCRG1,CCSER2,BDNF-AS,GNE,JMJD1C" MicroRNA hsa-miR-525-3p:PITA hsa-miR-525-3p:PITA_TOP PITA 5.78E-04 1.00E+00 9.25E-04 8.48E-03 4 30 "GRIN1,GPR88,CSDE1,SRGAP3" MicroRNA hsa-miR-524-3p:PITA hsa-miR-524-3p:PITA_TOP PITA 5.78E-04 1.00E+00 9.25E-04 8.48E-03 4 30 "GRIN1,GPR88,CSDE1,SRGAP3" MicroRNA hsa-miR-764:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.97E-04 1.00E+00 9.56E-04 8.77E-03 11 258 "PLEKHG5,WAC,CACNB2,CYB561A3,MFSD2A,P2RX7,ATCAY,FAM131B,KCNN3,GNE,BSCL2" MicroRNA hsa-miR-1237-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.01E-04 1.00E+00 9.61E-04 8.82E-03 8 144 "GALNT13,NLGN4X,SFMBT2,FAM69C,TNS1,HMGB1,NEGR1,KCNN3" MicroRNA hsa-miR-4273:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.06E-04 1.00E+00 9.70E-04 8.90E-03 6 80 "SOX1,BTF3L4,TOMM20,ST8SIA3,SH3GLB1,SEZ6" MicroRNA "TTGGGAG,MIR-150:MSigDB" "TTGGGAG,MIR-150:MSigDB" MSigDB 6.06E-04 1.00E+00 9.70E-04 8.90E-03 6 80 "ATAT1,TESK2,PKP4,IFFO1,NAV2,KCNN3" MicroRNA hsa-miR-6755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.08E-04 1.00E+00 9.72E-04 8.92E-03 5 53 "MDM4,PLEKHG5,ASPH,GNAS,BTF3L4" MicroRNA hsa-miR-605-5p:Functional MTI Functional MTI miRTarbase 6.19E-04 1.00E+00 9.88E-04 9.07E-03 7 111 "CACNA1A,GPM6B,CACNA1E,BTF3L4,PRDM2,RTN4,SFXN5" MicroRNA hsa-miR-6857-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.19E-04 1.00E+00 9.88E-04 9.07E-03 7 111 "FGF1,SMOC1,DDR2,NUCB1,MICAL2,CADM2,ZC3H11A" MicroRNA hsa-miR-4786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.19E-04 1.00E+00 9.88E-04 9.07E-03 7 111 "LGR4,KCNIP2,SFMBT2,SEPT3,TPM3,COL9A2,CACNG7" MicroRNA hsa-miR-599:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.19E-04 1.00E+00 9.88E-04 9.07E-03 7 111 "GAS7,PAX6,CTNND1,TOMM20,WIPF2,CACNG7,ABI2" MicroRNA hsa-miR-4505:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-04 1.00E+00 9.97E-04 9.14E-03 9 181 "ADAR,PNMA8B,MAGI3,SLIT1,RAP1GAP2,NEURL1,PTPA,RGS6,RAB5B" MicroRNA hsa-miR-4645-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-04 1.00E+00 1.00E-03 9.21E-03 8 145 "TOMM40L,DNAH17,DDR1,GPR26,HMGB1,NCAN,KCNH1,KCNJ11" MicroRNA hsa-miR-4304:mirSVR_highEffct hsa-miR-4304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.48E-04 1.00E+00 1.03E-03 9.48E-03 6 81 "ACER3,ARHGEF7,TCF7L2,GRIK2,DNM2,SEC61A2" MicroRNA hsa-miR-4717-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.48E-04 1.00E+00 1.03E-03 9.48E-03 6 81 "WAC,PALLD,TCF7L2,C11orf49,FAT3,CADM2" MicroRNA hsa-miR-758-3p:TargetScan hsa-miR-758-3p TargetScan 6.49E-04 1.00E+00 1.04E-03 9.50E-03 9 182 "ATP2B2,GAD2,GFAP,GRIK3,PAX6,REPS2,CADM1,GPR61,FGFBP3" MicroRNA hsa-miR-5787:Functional MTI Functional MTI miRTarbase 6.49E-04 1.00E+00 1.04E-03 9.50E-03 9 182 "ADAR,PNMA8B,MAGI3,SLIT1,RAP1GAP2,NEURL1,PTPA,RGS6,RAB5B" MicroRNA hsa-miR-188-5p:Non-Functional MTI Non-Functional MTI miRTarbase 6.53E-04 1.00E+00 1.04E-03 9.54E-03 7 112 "ADORA3,C10orf105,CACNA1A,VXN,PCDH9,MEAF6,PRDM2" MicroRNA hsa-miR-376a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 6.53E-04 1.00E+00 1.04E-03 9.54E-03 7 112 "FOXG1,GNAS,MYRF,INA,ATG4C,BTF3L4,KCND3" MicroRNA hsa-miR-1224-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.57E-04 1.00E+00 1.05E-03 9.59E-03 11 261 "FABP7,ZCCHC24,CACNA1A,CACNA1E,TCF12,ATCAY,TOMM20,KCNJ4,RABGAP1L,ABI2,ELAVL3" MicroRNA hsa-miR-511-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.57E-04 1.00E+00 1.05E-03 9.59E-03 11 261 "SYT9,FGF14,SOX5,TUB,NLGN3,CCSER2,SPATA6,ACBD5,DOCK7,SSPN,ABI2" MicroRNA hsa-miR-4532:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.58E-04 1.00E+00 1.05E-03 9.61E-03 8 146 "ECSIT,SLC7A14,KIAA1614,INKA2,RFFL,HMGB1,KIAA0408,PHYHIP" MicroRNA hsa-miR-8072:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.63E-04 1.00E+00 1.05E-03 9.67E-03 5 54 "PDZD4,DNAH17,NMNAT2,WSCD1,BRSK2" MicroRNA hsa-miR-4774-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.63E-04 1.00E+00 1.05E-03 9.67E-03 5 54 "LRRC55,POU3F2,PNKD,RAB5B,ABI2" MicroRNA hsa-miR-5004-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.63E-04 1.00E+00 1.05E-03 9.67E-03 5 54 "TBX15,PUM1,C1orf109,NKAIN1,TMEM100" MicroRNA hsa-miR-1298-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.63E-04 1.00E+00 1.05E-03 9.67E-03 5 54 "KIAA1614,PALLD,TCF7L2,NAV2,EN2" MicroRNA hsa-miR-3960:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.63E-04 1.00E+00 1.05E-03 9.67E-03 5 54 "PDZD4,DNAH17,NMNAT2,WSCD1,BRSK2" MicroRNA hsa-miR-4673:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-04 1.00E+00 1.09E-03 1.00E-02 8 147 "TOMM40L,DNAH17,DDR1,GPR26,HMGB1,NCAN,KCNH1,KCNJ11" MicroRNA hsa-miR-493:PITA hsa-miR-493:PITA_TOP PITA 6.91E-04 1.00E+00 1.10E-03 1.01E-02 6 82 "TESK2,CADPS,RCOR3,KCNMA1,DLG3,PAK5" MicroRNA hsa-miR-936:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.91E-04 1.00E+00 1.10E-03 1.01E-02 6 82 "CLIP1,CCDC80,ZFP91,ZNF384,RIMS3,BLOC1S6" MicroRNA hsa-miR-150-5p:Functional MTI Functional MTI miRTarbase 6.99E-04 1.00E+00 1.11E-03 1.02E-02 17 534 "TUBB4A,FOXRED2,DRAXIN,ZCCHC24,WWC1,ACSL6,ZEB1,VXN,MFSD2A,P2RX7,HMGB1,COL9A2,ATCAY,DPYSL5,OCIAD1,RABGAP1L,GNE" MicroRNA hsa-miR-382-5p:TargetScan hsa-miR-382-5p TargetScan 7.19E-04 1.00E+00 1.14E-03 1.05E-02 8 148 "GALNT13,GPR158,SCRG1,JAM2,NEGR1,RASGRF1,ELAVL4,EN2" MicroRNA hsa-miR-6768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.19E-04 1.00E+00 1.14E-03 1.05E-02 8 148 "WAC,TESK2,SESN3,GRID1,CD81,TPM3,PKN2,NOS1AP" MicroRNA hsa-miR-6845-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.21E-04 1.00E+00 1.14E-03 1.05E-02 11 264 "TUBB4A,ASIC4,ATP1A3,BCL2L2,GJB1,CDH8,TMPRSS5,PMEPA1,STMN4,SMG7,KCNJ11" MicroRNA "GTACAGG,MIR-486:MSigDB" "GTACAGG,MIR-486:MSigDB" MSigDB 7.22E-04 1.00E+00 1.14E-03 1.05E-02 5 55 "SORCS1,ARHGAP5,SMOC1,PPP3CB,SRGAP3" MicroRNA hsa-miR-514b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.25E-04 1.00E+00 1.15E-03 1.06E-02 7 114 "SDE2,VWCE,PTGDR2,CHRNB2,KIAA1549L,CCSER2,ELAVL4" MicroRNA hsa-miR-7153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.37E-04 1.00E+00 1.17E-03 1.07E-02 6 83 "PLEKHG5,RUFY2,TMEM136,GPM6B,TMPRSS5,MICAL2" MicroRNA hsa-miR-937-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.37E-04 1.00E+00 1.17E-03 1.07E-02 6 83 "SPART,FAM168A,CYB561A3,SCRG1,PLD5,JMJD1C" MicroRNA hsa-miR-4759:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.43E-04 1.00E+00 1.18E-03 1.08E-02 4 32 "TCF7L2,PSD3,KCNK1,RAB5B" MicroRNA "TAATGTG,MIR-323:MSigDB" "TAATGTG,MIR-323:MSigDB" MSigDB 7.52E-04 1.00E+00 1.19E-03 1.09E-02 8 149 "PKP4,SEPT3,CAMTA1,ANO4,GPM6A,PCDH9,NSD2,PAK5" MicroRNA hsa-miR-582-5p:Functional MTI Functional MTI miRTarbase 7.52E-04 1.00E+00 1.19E-03 1.09E-02 8 149 "CAPRIN2,TGFBR3,CD81,TPM4,PIK3CD,ZC3H11A,KCNC1,ELAVL3" MicroRNA hsa-miR-588:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.61E-04 1.00E+00 1.20E-03 1.10E-02 10 225 "GOLGA7B,ATP1A2,KIF21B,KIF1B,WWC1,ATCAY,FGFR1OP2,BLOC1S6,RABGAP1L,SIDT2" MicroRNA hsa-miR-146b-3p:PITA hsa-miR-146b-3p:PITA_TOP PITA 7.64E-04 1.00E+00 1.21E-03 1.11E-02 7 115 "SGIP1,ADGRL3,HAP1,ZFP91,RBFOX2,NXPH1,VANGL2" MicroRNA hsa-miR-3145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.84E-04 1.00E+00 1.24E-03 1.14E-02 5 56 "NEGR1,BTF3L4,ZBTB16,L1CAM,ZYG11B" MicroRNA hsa-miR-3619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-04 1.00E+00 1.24E-03 1.14E-02 8 150 "SCN4B,SFMBT2,DKK3,GANAB,TPM3,LRTM2,VAV2,NCAN" MicroRNA hsa-miR-376c-3p:Functional MTI Functional MTI miRTarbase 7.85E-04 1.00E+00 1.24E-03 1.14E-02 6 84 "ATAT1,GOLGA7B,ANK1,ATM,SNCB,RTN4" MicroRNA hsa-miR-376b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 7.85E-04 1.00E+00 1.24E-03 1.14E-02 6 84 "FOXG1,GNAS,MYRF,ATG4C,BTF3L4,KCND3" MicroRNA hsa-miR-4511:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-04 1.00E+00 1.24E-03 1.14E-02 6 84 "RTN3,MIER1,GJB1,GRIK4,KIAA0513,ABCC9" MicroRNA "ATGTCAC,MIR-489:MSigDB" "ATGTCAC,MIR-489:MSigDB" MSigDB 7.85E-04 1.00E+00 1.24E-03 1.14E-02 6 84 "SCN3A,UNC5D,BRSK2,POU3F2,RBM12,BAALC" MicroRNA hsa-miR-18b-5p:Functional MTI Functional MTI miRTarbase 8.04E-04 1.00E+00 1.27E-03 1.16E-02 7 116 "F3,WAC,ATM,GNAS,CRB1,PCDH9,TOMM20" MicroRNA hsa-miR-541-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-04 1.00E+00 1.32E-03 1.21E-02 6 85 "CAPRIN2,ARHGEF7,TGFBR3,CTNND1,PRDM2,KCNA6" MicroRNA hsa-miR-6842-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-04 1.00E+00 1.32E-03 1.21E-02 6 85 "MRVI1,ADAR,MAGI3,CACNA1A,NEURL1,RAB5B" MicroRNA hsa-miR-589-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-04 1.00E+00 1.32E-03 1.21E-02 6 85 "EPS8,FGF1,NPAS3,DAAM2,UBTF,BDNF-AS" MicroRNA hsa-miR-886-3p:mirSVR_highEffct hsa-miR-886-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.36E-04 1.00E+00 1.32E-03 1.21E-02 6 85 "CHST15,TTLL9,ANO4,NLGN3,PRDM2,KCNK1" MicroRNA hsa-miR-450b-3p:PITA hsa-miR-450b-3p:PITA_TOP PITA 8.36E-04 1.00E+00 1.32E-03 1.21E-02 6 85 "SMARCE1,STARD10,CELF3,DLGAP3,HP1BP3,DLG2" MicroRNA hsa-miR-99a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-04 1.00E+00 1.32E-03 1.21E-02 4 33 "GRAMD1B,PUM1,WIPF2,ABI2" MicroRNA hsa-miR-6832-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.40E-04 1.00E+00 1.32E-03 1.22E-02 11 269 "EPS8,API5,ATP1A2,TPM3,ZNF384,COL9A2,NSD2,KIAA0513,GNE,ZYG11B,EPB41L1" MicroRNA hsa-miR-6852-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.41E-04 1.00E+00 1.33E-03 1.22E-02 10 228 "MOG,LHFPL4,CNDP1,GPR26,OLR1,SCRG1,BTF3L4,ZBTB16,RABGAP1L,KCNK1" MicroRNA hsa-miR-6515-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.49E-04 1.00E+00 1.34E-03 1.23E-02 9 189 "GRAMD1B,DGKD,DKK3,MYBPC1,CYB561A3,PTGDR2,HMGB1,PNKD,NUP214" MicroRNA hsa-miR-891b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-04 1.00E+00 1.34E-03 1.23E-02 5 57 "CNDP1,TCF7L2,HMGB1,CSDE1,PTPRD" MicroRNA hsa-miR-1224-5p:TargetScan hsa-miR-1224-5p TargetScan 8.56E-04 1.00E+00 1.35E-03 1.24E-02 8 152 "ADORA1,FGF1,ITSN1,CCDC80,KIF21B,RIMS4,MAPK10,PRRT4" MicroRNA hsa-miR-1225-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.56E-04 1.00E+00 1.35E-03 1.24E-02 8 152 "RTKN,SCN4B,NSG2,GPR37L1,FTO,KIAA0513,TOMM20,ELAVL3" MicroRNA hsa-miR-3202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.66E-04 1.00E+00 1.36E-03 1.25E-02 11 270 "MAG,ZFYVE27,ARID1A,FAM168A,TMEM9,TMPRSS5,UBTF,PACSIN1,PTPA,FAM131B,NAV2" MicroRNA hsa-miR-125a-5p:Functional MTI Functional MTI miRTarbase 8.66E-04 1.00E+00 1.36E-03 1.25E-02 11 270 "EMID1,MEG3,PLEKHG5,TACC2,TMEM136,PC,TPM4,NEGR1,MAPK8,MASP1,ARHGAP12" MicroRNA hsa-miR-556-3p:PITA hsa-miR-556-3p:PITA_TOP PITA 8.81E-04 1.00E+00 1.39E-03 1.27E-02 9 190 "ADGRL3,EML4,TMEM257,FAT3,MED1,PPP2R5C,CTNND1,SIRPA,PID1" MicroRNA hsa-miR-769-3p:PITA hsa-miR-769-3p:PITA_TOP PITA 8.89E-04 1.00E+00 1.40E-03 1.28E-02 6 86 "SMARCE1,STARD10,CELF3,DLGAP3,HP1BP3,DLG2" MicroRNA hsa-miR-4662a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.93E-04 1.00E+00 1.40E-03 1.29E-02 8 153 "API5,SPART,GPR26,AKNA,FAT3,OSBPL3,ZYG11B,UEVLD" MicroRNA "CAAGGAT,MIR-362:MSigDB" "CAAGGAT,MIR-362:MSigDB" MSigDB 9.21E-04 1.00E+00 1.45E-03 1.33E-02 5 58 "LRRTM4,SGIP1,PSD3,RIMS4,KCNMA1" MicroRNA hsa-miR-4719:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-04 1.00E+00 1.46E-03 1.34E-02 8 154 "SRARP,SYT4,OLR1,KIAA1549L,CCSER2,FAT3,OCIAD1,SSPN" MicroRNA hsa-miR-6798-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.81E-04 1.00E+00 1.54E-03 1.41E-02 7 120 "WAC,PNMA8B,SESN3,NFASC,ZFP91,HMGB1,UBTF" MicroRNA hsa-miR-1470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.84E-04 1.00E+00 1.54E-03 1.42E-02 9 193 "SRARP,PNMA8B,SHANK2,INKA2,CDH8,SLC22A6,TENM4,ZBTB16,SMG7" MicroRNA hsa-miR-3187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.92E-04 1.00E+00 1.56E-03 1.43E-02 10 233 "GOLGA7B,ATP1A2,KIF1B,WWC1,ATCAY,FGFR1OP2,BLOC1S6,RABGAP1L,SIDT2,ABI2" MicroRNA hsa-miR-3937:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.95E-04 1.00E+00 1.56E-03 1.43E-02 5 59 "CLSTN1,B4GALNT4,CD81,PHYHIP,ABI2" MicroRNA hsa-miR-1227:PITA hsa-miR-1227:PITA_TOP PITA 1.00E-03 1.00E+00 1.57E-03 1.44E-02 6 88 "NEGR1,POU3F2,PNKD,HP1BP3,KCNMA1,PHC2" MicroRNA hsa-miR-493-3p:Functional MTI Functional MTI miRTarbase 1.00E-03 1.00E+00 1.57E-03 1.44E-02 6 88 "ARHGAP5,BTRC,CSDE1,SMG7,KCNJ4,SH3GLB1" MicroRNA hsa-miR-4272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-03 1.00E+00 1.57E-03 1.44E-02 6 88 "ADAR,SYT4,FBXL16,RBFOX2,NEGR1,ACBD5" MicroRNA hsa-miR-3120-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-03 1.00E+00 1.59E-03 1.46E-02 8 156 "MDM4,URGCP,RUFY2,NAXD,EMC1,OLR1,PTPA,NAV2" MicroRNA hsa-miR-760:Functional MTI Functional MTI miRTarbase 1.02E-03 1.00E+00 1.60E-03 1.47E-02 9 194 "RTN3,TOMM40L,SON,FBXL16,UBTF,PUM1,WBP1L,PMEPA1,RAB5B" MicroRNA hsa-miR-2116-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-03 1.00E+00 1.65E-03 1.52E-02 8 157 "GRAMD1B,TUBB4A,ZCCHC24,CASTOR3,ACSL6,GPR26,CAMK2G,DPYSL5" MicroRNA hsa-miR-5585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-03 1.00E+00 1.66E-03 1.53E-02 6 89 "SLC7A14,RCOR3,LUZP2,NUDT21,RBPJ,DOCK7" MicroRNA hsa-miR-580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-03 1.00E+00 1.66E-03 1.53E-02 6 89 "SON,ARHGEF7,TNR,ZFYVE9,TOMM20,CACNG7" MicroRNA hsa-miR-3934-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-03 1.00E+00 1.67E-03 1.53E-02 11 277 "WAC,FOXRED2,CACNB2,NRGN,MFSD2A,P2RX7,ATCAY,FAM131B,KCNN3,GNE,BSCL2" MicroRNA hsa-miR-145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-03 1.00E+00 1.68E-03 1.54E-02 5 60 "ACER3,CADM3,GUCY1A2,TMCC2,JMJD1C" MicroRNA hsa-miR-4271:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.71E-03 1.57E-02 10 236 "ZFYVE27,RTN3,DRAXIN,PKNOX2,WDTC1,BTRC,GPR26,CECR2,OLR1,WBP1L" MicroRNA hsa-miR-6780b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-03 1.00E+00 1.76E-03 1.62E-02 6 90 "WAC,BCAN,CACNA1A,TMEFF2,TLX1,PHKG1" MicroRNA hsa-miR-210-3p:Functional MTI Functional MTI miRTarbase 1.13E-03 1.00E+00 1.77E-03 1.63E-02 7 123 "APC,NCAM1,CLASP2,KCNK10,DOCK7,RAD52,EFNA3" MicroRNA hsa-miR-1233-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-03 1.00E+00 1.77E-03 1.63E-02 9 197 "NRGN,PFKFB3,NEGR1,UBTF,FAM131B,TOMM20,PHC2,EFNA3,ABI2" MicroRNA hsa-miR-6794-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-03 1.00E+00 1.79E-03 1.64E-02 8 159 "SRARP,INKA2,CNDP1,KLHL4,TMEM151B,FBXL16,RGS6,TMCC2" MicroRNA hsa-miR-212-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-03 1.00E+00 1.79E-03 1.64E-02 8 159 "DRAXIN,NASP,GNAS,WWC1,CACNA1A,TJP1,HMGB1,COL9A2" MicroRNA hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-03 1.00E+00 1.81E-03 1.66E-02 5 61 "MAPT,CLIP1,MYBPC1,SF1,SIRPA" MicroRNA "CCACACA,MIR-147:MSigDB" "CCACACA,MIR-147:MSigDB" MSigDB 1.16E-03 1.00E+00 1.81E-03 1.66E-02 5 61 "ACLY,ANK1,AHCYL1,CAMTA1,GRID1" MicroRNA hsa-miR-409-5p:mirSVR_highEffct hsa-miR-409-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-03 1.00E+00 1.81E-03 1.66E-02 11 280 "MOBP,PHYHIPL,CAMTA1,GPM6A,SPATA6,ATRNL1,PUM1,DNAJC6,LRP8,KCNK1,OLIG1" MicroRNA hsa-miR-144-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-03 1.00E+00 1.82E-03 1.67E-02 4 36 "MDM4,ADARB2,ACSBG1,PCSK2" MicroRNA hsa-miR-2278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.85E-03 1.70E-02 7 124 "GRAMD1B,DNAH17,AJAP1,TPM3,PACSIN1,WIPF2,EFNA3" MicroRNA hsa-miR-525-3p:mirSVR_highEffct hsa-miR-525-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-03 1.00E+00 1.85E-03 1.70E-02 7 124 "ITSN1,API5,SLIT1,ADGRL3,GPR88,MICAL2,CSDE1" MicroRNA hsa-miR-4292:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.85E-03 1.70E-02 7 124 "RIMKLA,NCDN,FAM168A,GPR26,BEST3,CHRNB2,VAV2" MicroRNA hsa-miR-4691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.85E-03 1.70E-02 7 124 "SDE2,YPEL4,BCL2L2,MFSD2A,TMEFF2,CTNND1,PTCH1" MicroRNA hsa-miR-1908:mirSVR_highEffct hsa-miR-1908:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-03 1.00E+00 1.85E-03 1.70E-02 8 160 "ADAR,PPFIA1,ANO4,OPALIN,PLCH2,SMG7,EPB41L1,SEZ6" MicroRNA hsa-miR-30d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.85E-03 1.70E-02 8 160 "MDM4,SLC1A2,NBPF1,CACNA1E,NUCB1,PCSK2,CAMKV,KCNN3" MicroRNA hsa-miR-920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.86E-03 1.70E-02 6 91 "LHFPL4,NFASC,ADGRG1,NEGR1,VAV2,PTPA" MicroRNA hsa-miR-6726-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.86E-03 1.70E-02 6 91 "LHFPL4,NFASC,ADGRG1,NEGR1,VAV2,PTPA" MicroRNA hsa-miR-5591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.86E-03 1.70E-02 6 91 "LHFPL4,NFASC,ADGRG1,NEGR1,VAV2,PTPA" MicroRNA hsa-miR-887:mirSVR_lowEffct hsa-miR-887:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-03 1.00E+00 1.87E-03 1.72E-02 12 325 "ASCL1,CAPRIN2,ATP2B2,GAD2,ZEB1,GRIA2,BTF3L4,CP,VCAN,PLPPR1,MAGI2,RAP1GAP" MicroRNA hsa-miR-6790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-03 1.00E+00 1.91E-03 1.75E-02 11 282 "KIF1B,CACNB2,GPR26,VXN,P2RX7,HMGB1,MEAF6,ATCAY,BLOC1S6,KCNN3,UEVLD" MicroRNA hsa-miR-1307-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-03 1.00E+00 1.92E-03 1.77E-02 10 240 "SRARP,KIAA1614,SHANK2,NEK6,ACSL6,VWC2,HMGB1,DOCK7,PTAFR,GNE" MicroRNA hsa-miR-4480:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-03 1.00E+00 1.93E-03 1.77E-02 7 125 "KCNIP2,ADCYAP1R1,GPAM,SNAP25,RGS6,MAPK8,C1orf109" MicroRNA hsa-miR-6796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.96E-03 1.80E-02 6 92 "SLC7A14,WWC1,PAX6,KIAA0408,WIPF2,ABI2" MicroRNA hsa-miR-4300:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.96E-03 1.80E-02 6 92 "LHFPL4,NFASC,ADGRG1,NEGR1,VAV2,PTPA" MicroRNA "ATGCACG,MIR-517B:MSigDB" "ATGCACG,MIR-517B:MSigDB" MSigDB 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "TBX15,CAMK2G,NRXN1" MicroRNA "AGCGCTT,MIR-518F:MSigDB" "AGCGCTT,MIR-518F:MSigDB" MSigDB 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "NSG2,SON,NRXN1" MicroRNA "AGCGCTT,MIR-518A:MSigDB" "AGCGCTT,MIR-518A:MSigDB" MSigDB 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "NSG2,SON,NRXN1" MicroRNA "AGCGCTT,MIR-518E:MSigDB" "AGCGCTT,MIR-518E:MSigDB" MSigDB 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "NSG2,SON,NRXN1" MicroRNA hsa-miR-886-3p:PITA hsa-miR-886-3p:PITA_TOP PITA 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "SDE2,GOLGA7B,NLGN3" MicroRNA hsa-miR-572:PITA hsa-miR-572:PITA_TOP PITA 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "NCAM1,BCL2L2,VSTM2A" MicroRNA hsa-miR-1908-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "DNAH17,PLD5,EPB41" MicroRNA hsa-miR-4730:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-03 1.00E+00 1.97E-03 1.81E-02 3 17 "FBXL16,GPR37L1,MICAL2" Drug ctd:C029790 "2,2',3',4,4',5-hexachlorobiphenyl" CTD 2.88E-22 9.36E-18 9.36E-18 1.03E-16 164 1885 "MAG,SDE2,MAP6,ACHE,ACLY,APC2,MBP,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,RTN1,DSCAML1,SORCS1,FCGR1A,CHST15,DRAXIN,SNX32,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,MOG,SOX6,FOXM1,AMPH,CDC42BPA,ANK1,ANK3,ITSN1,ANXA7,SH3GL2,PPM1E,GAS7,CLSTN1,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,SLCO1A2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,SNAP25,ATM,ATP1A2,NRG3,ATP1A3,ATP2B2,USP33,KIF21B,NMNAT2,KIF1B,NASP,NCAM1,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,GNAS,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GRIN1,GPR88,VWCE,OMG,OPCML,PTPN5,TIE1,NEURL1,PC,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,DLGAP3,CPT1C,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,ACBD5,MFSD4A,POU3F2,ETNPPL,PTPA,MICAL2,PLCH2,PRKACB,DOCK7,CALY,PRKCG,ARHGEF4,CTNND1,NRSN1,BRINP3,PSD,SYTL2,DPYSL5,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,RGMA,MAGI2,KCND3,SV2A,NTM,AK5,KCNMA1,NAV2,KCNQ2,DLG2,PYGM,RAB5B,TMEM255A,DNM2,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,PIANP,EFNA3,SLC4A10,EPB41L1" Drug ctd:D003042 Cocaine CTD 1.54E-19 5.01E-15 2.50E-15 2.75E-14 124 1317 "ABAT,MAP6,MBP,SYT9,RCSD1,ACTN2,EYA1,RTKN,NDRG2,CLIP1,ADCY2,SLITRK1,PNMA8B,ADORA1,AGT,PLA2G6,LRRC7,SEMA6A,C1QTNF4,HPCAL4,MOBP,SEMA6C,ANXA7,SYBU,SLC1A2,PKNOX2,ARHGAP5,CCDC88A,SHANK2,SLC14A1,CSPG5,TAGLN3,SORCS3,ADGRA1,ATM,SNCB,ATP1A3,GABBR1,SON,GAD2,MYH7,ARPP21,ERBIN,GFAP,KIRREL3,GJB1,ARHGEF7,SYT4,NKX2-2,SEMA4A,ADGRL3,GPM6A,GPM6B,ATF7,NPPA,CAMK2A,DDR2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GPR88,GRM3,TF,CCKBR,INA,GUCY1A1,AIFM1,CD81,TNFRSF1B,PCDH8,SEZ6L,TPM3,PCSK2,PDYN,FNDC5,CHRM4,CHRNB2,GDAP1L1,SEMA5B,UBTF,TJP2,NECAB2,RNF14,SNCAIP,TENM4,NCAN,CALY,PRKCG,PRKCZ,CTNND2,MAPK8,MAPK10,ZBTB16,ACY3,ANKS1B,JAKMIP2,PMEPA1,ELMO1,PRDM2,KCNA2,KCNA6,KCND3,KCNJ4,KCNJ10,KCNJ11,SNX27,DLG2,CAB39L,DNM2,SLC17A6,RASGRF1,ABCC9,CRTAC1,CAMK1G,EEF1A2,PIANP,EFNA3,RBM12,SLC4A10,BSCL2,BAALC" Drug CID005183170 AC1NPPZW Stitch 3.08E-16 9.99E-12 3.33E-12 3.65E-11 28 103 "ASIC1,KCNIP2,SCN4B,FGF14,ASIC4,ANK2,ANK3,FOLH1,BCAN,SCN3B,NEUROD1,ZEB1,INA,ASIC3,SERPINE2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,NTM,KCNJ10,KCNK2,PCDH15,NAV2,ABI1,ABI2" Drug ctd:C496932 panobinostat CTD 6.43E-15 2.09E-10 5.22E-11 5.72E-10 114 1335 "ABAT,MAP6,ASIC1,TMEM74,ADGRV1,WLS,SLC25A25,RTN1,ADCYAP1R1,AMER2,CHST15,SCN4B,C1QTNF4,ELMOD1,USP28,GAS7,NLGN1,SFMBT2,LRRC55,PKNOX2,ARHGAP5,DACH2,ASCL1,SCG3,CSPG5,SLIT1,ASTN1,SNAP25,TNIK,SOX10,GAD2,NMNAT2,SALL3,DNER,NFASC,LMO3,COLGALT2,STOX1,SMOC1,NELL1,AJAP1,FAM168A,GLS,SYT4,ASTN2,POPDC3,DCLK2,GNAS,CNTN2,ADGRL3,WWC1,PRUNE2,FAM69C,CACNB2,ZEB1,GRIA1,GRIK3,GRM3,OPCML,CCKBR,PTPN5,GUCY1A1,KCNK10,PAX6,IGSF21,PCDH8,CDH8,CDH10,DCLK1,PDYN,ZMYND8,FNDC5,ADGRG1,SCRG1,CHGA,NRXN2,NEGR1,CCDC136,CNTN1,CELF5,PRRX1,NSD2,FAT3,CNRIP1,FEZ1,KIAA1755,CTNND2,MAPK10,HES5,ZBTB16,TOX,SYTL2,ANKS1B,ZNF385B,PMEPA1,LRP8,RGMA,MAGI2,OLFM3,KCNC1,PTPRO,RABGAP1L,ARNT2,KCNK1,KCNN3,PID1,FAM13C,L1CAM,ST8SIA3,RFX4,FGFBP3,LPAR6,RASGRP2,SEZ6" Drug ctd:C042720 mercuric bromide CTD 1.30E-14 4.24E-10 8.47E-11 9.29E-10 98 1077 "MAP6,ASIC1,TMEM74,CNTNAP3,SYT9,F3,ADCY2,SLITRK1,ADCYAP1R1,SORCS1,AMER2,SEMA6A,ELMOD1,SOX6,ANK1,USP28,APBA2,CACHD1,SYBU,SHTN1,SLC1A2,BCO1,PKNOX2,GPR153,CSPG5,ASTN1,PALLD,SOX1,TNIK,JPH4,SALL3,LHFPL4,NFASC,NCAM1,LMO3,COLGALT2,STOX1,SMOC1,AJAP1,GLS,DCLK2,GNAS,ROBO3,CNTN2,KLHL4,PRUNE2,GPM6A,GPM6B,FAM69C,CACNB2,DDR2,CCKBR,KCNK10,PAX6,REPS2,IGSF21,PCDH8,PCDH9,CDH10,HRH3,PDE4B,FNDC5,JAM2,GDAP1L1,TJP2,CCDC136,CELF5,POU3F2,SNCAIP,FEZ1,OSBPL3,NCAN,DOCK7,CTNND2,MAPK10,HES5,ZBTB16,TOX,ZNF385B,DNAJC6,CADM2,RGMA,OLFM3,KCNK1,KCNQ2,PYGM,CAB39L,GNE,FAM13C,DTNA,SLC6A15,RET,RFX4,RGS7,SFXN5,LMO1,LPAR6,SEZ6" Drug ctd:C410127 PCB 180 CTD 2.59E-14 8.41E-10 1.34E-10 1.46E-09 132 1683 "SERPINA3,MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ANK3,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,SLCO1A2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,TMEM108,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ACSBG1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,KLHL4,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,GRIA4,RFFL,GRIN1,GPR88,GRM3,VWCE,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,DLGAP3,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,HES5,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,AK5,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10,EPB41L1" Drug CID000001727 4-AP Stitch 3.26E-14 1.06E-09 1.34E-10 1.46E-09 41 258 "ACHE,KCNIP2,ADORA1,ADORA3,SCN4B,MTR,ATP1A2,ATP1A3,SCN3B,MYBPC1,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,GUCY1A2,KCNK10,ASIC3,CHRM1,UBTF,PRKCG,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,EPB41" Drug ctd:D019422 Dietary Sucrose CTD 3.53E-14 1.15E-09 1.34E-10 1.46E-09 89 946 "TTYH1,ACLY,APC2,RCSD1,ADCY2,SLITRK1,CDC7,ERMN,GRAMD1B,SNX32,BBOX1,ELMOD1,SELL,JAKMIP3,ST8SIA1,RPH3A,MT3,NSG2,DACH2,LGI3,DNAH17,DLL3,BRINP2,SORCS3,B3GAT1,GABBR1,SCN3B,SOX10,MYH7,LHFPL4,NFASC,GPR162,RCOR2,NELL1,MLC1,MMD2,ADGRL3,CACNA1E,NPPA,DIRAS1,GPR26,HAP1,CAMK2A,GRIN1,OLR1,TLL2,TNR,PCDH8,HRH3,PIRT,TMPRSS5,PFKFB3,GDAP1L1,FADS2,SULT4A1,CELF5,BEST1,ATCAY,BTBD17,MFSD4A,POU3F4,TENM4,CSF3R,RIMS4,PLD5,SLC45A1,IGSF1,FAM131B,NOS1AP,TOX,CDH20,KCNA6,PTPRZ1,KCNJ4,KCNJ9,ARNT2,KCNK2,KCNMA1,KCNQ2,CALN1,SLC25A18,DBX2,CAMK1G,RGS7,VANGL2,SLC39A12,CBLN2,RAVER2,PRRT4" Drug ctd:C009407 "2,5,2',5'-tetrachlorobiphenyl" CTD 3.70E-14 1.20E-09 1.34E-10 1.46E-09 132 1691 "MAP6,ACHE,APC2,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,RYR1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ANK3,CNIH2,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,PRLHR,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,GRM3,OMG,OPCML,PTPN5,TIE1,TMEM9,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,RGS6,FEZ2,MICAL2,PLCH2,DOCK7,CALY,ARHGEF4,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,MAGI2,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,DNM2,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug CID000004376 N-methyl-DL-aspartic acid Stitch 5.36E-14 1.74E-09 1.74E-10 1.91E-09 70 655 "EPS8,ACHE,ADGRV1,RYR1,ADORA1,ADORA3,SCN4B,LRRC7,FOLH1,APBA2,NLGN1,SLC1A2,RPH3A,SLC1A7,SLC6A9,SHANK2,B3GAT1,NRG3,FYN,SCN3B,SOX10,GAD2,NCAM1,GFAP,GLS,GNAS,CACNA1A,CACNA1E,CACNB2,NRGN,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,GUCY1A2,AIFM1,PAH,MAGI1,PDE2A,PDYN,ASIC3,CHRM1,CHRNB2,CAMKV,PIK3CD,PRKACB,PRKCG,PKN2,PRKCZ,NOS1AP,PTCH1,LRP8,MAGI2,KCNA1,KCNA4,DLG2,DLG3,RAB5B,SLC17A6,RASGRF1,CAMK1G,NUP214,CACNG7" Drug CID000005070 riluzole Stitch 6.31E-14 2.05E-09 1.86E-10 2.04E-09 33 174 "ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC1A2,NRG3,SCN3B,NFASC,GFAP,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,ZFP91,KCNK10,ASIC3,STMN4,KCNA4,KCNC1,KCND3,KCNK1,KCNK2,KCNN3,CACNG7" Drug ctd:C081766 "2,4,4'-trichlorobiphenyl" CTD 7.63E-14 2.48E-09 2.06E-10 2.26E-09 117 1437 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug ctd:C009828 "2,4,5,2',5'-pentachlorobiphenyl" CTD 1.36E-13 4.41E-09 3.39E-10 3.72E-09 118 1467 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,RYR1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug CID000005413 tetraethylammonium Stitch 1.86E-13 6.05E-09 4.32E-10 4.74E-09 38 236 "ASIC1,ACHE,SCN4B,MTR,ATP1A2,ATP1A3,SCN3B,MYBPC1,NCDN,CACNB2,INA,GUCY1A2,KCNK10,HRH3,ASIC3,CHRM1,SLC22A6,NRXN2,UBTF,PRKACB,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2" Drug CID000000611 glutamate Stitch 2.45E-13 7.94E-09 5.29E-10 5.81E-09 88 962 "ABAT,ASIC1,MAPT,ACHE,ADAR,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,SCN4B,SEMA6A,ACTL6B,FOXM1,FOLH1,AQP4,SLC1A2,SLC1A6,SLC1A7,SLC6A9,CSPG5,MTR,B3GAT1,ALDH4A1,SNAP25,ATP1A2,SCN3B,SOX10,GAD2,NMNAT2,GART,CPLX2,DNER,NPAS3,NFASC,GFAP,GLS,SYT4,GNAS,CACNA1A,CACNA1E,CACNB2,NRGN,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,P2RX7,AIFM1,ZFP91,PAH,PC,TPM3,PDYN,CHI3L2,ASIC3,CHRM1,CHRNB2,SULT4A1,ATCAY,ETNPPL,CALY,PRKCG,PKN2,PRKCZ,MAPK10,KLK6,ACY3,STMN4,KCNA1,KCNA2,KCNA4,SV2A,KCNJ10,KCNMA1,DLG2,SLC17A6,SLC25A18,EEF1A2,CACNG7,OLIG2" Drug ctd:C030370 "2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone" CTD 7.03E-13 2.28E-08 1.43E-09 1.57E-08 44 320 "MAG,NDRG2,TUBB4A,BBOX1,ANK2,RPH3A,CSPG5,SNAP25,GAD2,AHCYL1,KIF1B,LMO3,CLASP2,GFAP,CAMSAP2,MYRF,PRUNE2,TF,OPCML,CDC42,PCDH8,PCDH9,RBFOX2,TPD52,SCRG1,CHGA,PFKFB3,PLEKHB1,HNRNPK,HPCA,NRXN1,NRXN2,CNTN1,COL9A2,ETNPPL,PRKACB,CTNND2,ZBTB16,TUBB2B,SV2A,KCNQ2,RALGDS,RTN4,EPB41L1" Drug CID000020382 tetradotoxin Stitch 8.11E-13 2.63E-08 1.55E-09 1.70E-08 52 428 "ASIC1,ACHE,ADCYAP1R1,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ASIC4,FOXM1,ANK3,MTR,B3GAT1,ATP1A2,ATP1A3,SCN3B,GAD2,NKX6-2,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CCKBR,INA,GUCY1A2,P2RX7,HRH3,PDYN,NTSR2,ASIC3,CHRM1,CHRNB2,P2RY12,PRKCG,PKN2,PRKCZ,PTCH1,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCND3,KCNMA1,KCNN3" Drug CID000000119 gamma-aminobutyric acid Stitch 1.15E-12 3.73E-08 2.07E-09 2.27E-08 55 474 "ABAT,MAPT,ACHE,RYR1,ADORA1,ADORA3,AGT,SCN4B,SEMA6A,AMPH,SLC1A2,SLC1A6,SLC1A7,SLC6A9,ASCL1,B3GAT1,SNAP25,GABBR1,GAD2,GFAP,GLS,CNDP1,CACNA1A,CACNA1E,NPPA,CACNB2,ZEB1,HAP1,AZIN2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,PC,TPM3,PDYN,CHRM1,CHRNB2,SULT4A1,ETNPPL,PTCH1,STMN4,KCNA1,SV2A,KCNMA1,SLC17A6,DTNA,SLC6A15,EEF1A2,CACNG7" Drug ctd:D013759 Dronabinol CTD 3.32E-12 1.08E-07 5.67E-09 6.21E-08 82 908 "MAP6,MBP,SYT9,RTN3,ACTN2,KCNIP2,RYR1,FABP7,TUBB4A,FGF1,HPCAL4,MOBP,FOXM1,APBB1,NTNG1,BCAS1,AQP4,RPH3A,SLC6A9,NSG2,TAGLN3,ADGRA1,FYN,ARPP21,NCAM1,BCL2L2,GFAP,PHLDB1,MLC1,DCLK2,GOLGB1,ACSL6,HAP1,CAMK2A,DDR2,GRIA1,GRIK3,GPR88,TF,OPCML,GUCY1A1,NEURL1,CDC42,LGI1,TPD52,PDYN,PLEKHB1,HNRNPK,TMEFF2,HPCA,SERPINE2,NRXN1,OPALIN,CCDC136,MFSD4A,CRMP1,PPP2R5C,PPP3CB,CMTM5,PKN2,IGSF1,MAPK8,KLK6,PMEPA1,KCNA1,PTPRE,NTM,AK5,RABGAP1L,KCNMA1,SNX27,OLIG1,SLC17A6,RALGDS,RASGRF1,RTN4,L1CAM,SLC6A15,CRTAC1,ZYG11B,ST8SIA3,YY1AP1" Drug ctd:D000447 Aldehydes CTD 4.96E-12 1.61E-07 7.81E-09 8.56E-08 70 720 "ABAT,MAPT,TMEM74,SYT9,CEND1,MEG3,FAM43B,DSCAML1,SCN4B,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,CNIH2,SORBS1,SLC1A2,ZNF365,KIAA1614,SFMBT2,SLC8A2,SLN,TMEM108,TMEM151A,FYN,JPH4,TTC9B,NFASC,ALDH1L1,GFRA1,RCOR2,SEPT3,CAMTA1,WSCD1,DIRAS1,TF,OLR1,LINC00839,INA,ZDHHC22,PADI2,DCLK1,PDE2A,ARHGAP22,DUSP26,SERPINE2,NRXN2,CAMKV,NECAB2,ATCAY,BTBD17,CP,FEZ1,CHD5,RIMS4,ARHGEF4,IGSF1,RIMS3,DPYSL5,PMEPA1,CCDC3,PID1,KLRC3,TMEM255A,RAP1GAP,L1CAM,SLC6A15,RET,EEF1A2,PRRT4" Drug ctd:C046012 pentanal CTD 5.24E-12 1.70E-07 7.81E-09 8.56E-08 117 1531 "ABAT,MAPT,TMEM74,MBP,CNTNAP3,SYT9,CEND1,MEG3,FAM43B,ATAT1,DSCAML1,SCN4B,PLA2G6,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,SORBS1,BCAS1,SLC1A2,ZNF365,MIER1,SFMBT2,SLC8A2,RTP5,SLC14A1,SPHKAP,SLN,SORCS3,TMEM108,ATM,TMEM151A,ATP1A3,FYN,MEGF11,DKK3,CADM3,NMNAT2,JPH4,TTC9B,NFASC,GPR162,GFRA1,RCOR2,SEPT3,NFIA,ARHGEF7,DCLK2,CAMTA1,GOLGB1,WSCD1,DIRAS1,NRGN,GRIK2,ADAMTS8,TF,OLR1,CCKBR,LINC00839,MFSD2A,FBXL16,INA,CELF3,ZDHHC22,PADI2,PCDH9,DCLK1,PDE2A,CHI3L2,PLEKHB1,CASC2,ARHGAP22,DUSP26,DLGAP3,SERPINE2,NRXN2,CAMKV,HPR,FTO,COL9A2,NECAB2,ATCAY,BTBD17,CP,CRMP1,FEZ1,CHD5,RIMS4,PRKACB,SDC3,CMTM5,ARHGEF4,IGSF1,MAPK8,MAPK10,RIMS3,DPYSL5,ANKS1B,TUBB2B,PMEPA1,CCDC3,KCNMA1,PID1,KLRC3,TMEM255A,FAM66C,RAP1GAP,L1CAM,SLC6A15,RET,ZNF248,EEF1A2,CACNG7,PIANP,PRRT4,RASGRP2" Drug ctd:C005556 propionaldehyde CTD 5.29E-12 1.72E-07 7.81E-09 8.56E-08 141 1982 "ABAT,MAP6,MAPT,TMEM74,SYT9,CEND1,MEG3,ADGRV1,FAM43B,MRVI1,WLS,PLEKHG5,DSCAML1,SLC44A5,AGT,SCN4B,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,FOXM1,TRIM46,AMPH,PI16,CNIH2,SESN3,SORBS1,ST3GAL3,SLC1A2,ZNF365,SFMBT2,MSRA,SLC8A2,YPEL4,SHANK2,SLC14A1,SLN,TMEM108,ALDH4A1,TMEM151A,ATP1A2,FYN,PALLD,MEGF11,DKK3,MYBPC1,TNIK,NMNAT2,JPH4,TTC9B,IDI2-AS1,CPLX2,DNER,NFASC,C11orf87,ALDH1L1,GFRA1,RCOR2,KIRREL3,GJB1,SEPT3,ASTN2,KAZN,CAMTA1,UNC5D,PSRC1,WSCD1,NEU4,DIRAS1,CECR2,VWCE,TF,OLR1,LINC00839,CRB1,INA,ZDHHC22,PAX6,TNR,PADI2,DCLK1,LILRA4,PDE2A,FNDC5,GPR37L1,PLEKHB1,MS4A7,HPCA,ARHGAP22,DUSP26,SERPINE2,KIAA1549L,NRXN2,CAMKV,ANLN,CPT1C,ST8SIA5,PLXNB3,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,MFSD4A,CP,FEZ1,CHD5,RIMS4,ARHGEF4,SLC45A1,IGSF1,CTNND2,RIMS3,SYTL2,DPYSL5,PMEPA1,ITIH2,CADM2,CNIH3,RGMA,CCDC3,KCNMA1,KCNN3,PID1,TMEM255A,SLC25A41,RAP1GAP,L1CAM,SLC6A15,CRTAC1,RET,INSYN2,EEF1A2,VANGL2,CACNG7,PIANP,FGFBP3,PRRT4,RASGRP2" Drug ctd:C015001 arsenite CTD 2.01E-11 6.53E-07 2.76E-08 3.02E-07 126 1732 "RPL38,SYNDIG1,ACTN2,NDRG2,WAC,ERMN,CHST15,GPR158,SEMA6A,SEMA6C,SFPQ,SGIP1,CDC42BPA,ANK2,FOLH1,DGKZ,DGKD,SLITRK3,BCAN,CACHD1,API5,DACH2,CADPS,TAGLN3,SORCS3,SNAP25,SNCB,TNIK,SOX5,GAD2,NMNAT2,ENKUR,GART,CPLX2,NAP1L2,LMO3,SMOC1,NELL1,NEUROD1,NKX2-2,GNAS,GNG4,ANO4,TBX15,DDR1,CACNB2,PRLHR,CLEC9A,PCDHGA3,SYT6,GRIA2,GRIA4,GRIK3,GRIN1,TF,OPCML,USP2,INA,AIFM1,ZFP91,PAX6,TNFRSF1B,PCDH8,PCDH9,CDH8,LGI1,PCSK2,CIART,CHRM1,TMEFF2,JAM2,SERPINE2,NRXN2,TJP2,ST8SIA5,PLXNB3,CNTN1,CABP1,COL9A2,SPATA6,IFFO1,NXPH1,POU3F4,KCNT2,FEZ1,VCAN,RBPJ,PKN2,NRSN1,MAPK8,MAPK10,PROX1,BRINP3,TOX,SIRPA,PTCH1,DNAJC6,ITGAV,CA10,PTHLH,ELMO1,PRTFDC1,MAGI2,STMN4,KCNA1,PTPRE,KCNC1,PTPRZ1,KCNK2,KCNQ2,PYGM,DNAH9,TMEM255A,CALN1,SLC17A6,RAP1GAP,DBX2,DTNA,ST8SIA3,EEF1A2,RNF220,VWA5A,OLIG2,TMEM100,EPB41L1,SEZ6" Drug CID000000813 potassium Stitch 2.04E-11 6.62E-07 2.76E-08 3.02E-07 86 1009 "ASIC1,KCNIP2,ADCY2,RYR1,ADORA1,ADORA3,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,BBOX1,FOXM1,ANK3,AQP4,SLC1A2,SLC1A6,SLC1A7,SLC8A2,SLC8A3,SLC14A1,NAXD,MTR,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,GART,GFAP,ABCC8,GLS,OS9,NODAL,CACNA1A,CACNA1E,DDR1,NPPA,CACNB2,GRIK4,CYB561A3,GRM3,TF,LEFTY2,INA,GUCY1A2,P2RX7,KCNK10,RBFOX2,HRH3,PDE3B,ASIC3,CHRM1,CHRNB2,HPCA,PIK3CD,POU3F4,PTPA,KCNT2,PRKACB,PRKCG,PKN2,PRKCZ,KLK6,PTCH1,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,SV2A,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,DPP6,ABCC9,RGS7,CACNG7" Drug CID000003355 flecainide Stitch 2.49E-11 8.10E-07 3.24E-08 3.55E-07 19 71 "SERPINA3,ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNB2,ASIC3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNK1,DPP6" Drug ctd:D005419 Flavonoids CTD 8.15E-11 2.65E-06 1.02E-07 1.12E-06 92 1142 "MAG,ASIC1,ACLY,KCNIP2,ADARB2,RTN1,ADCY2,ADCYAP1R1,ADD3,AGT,SCN3A,MOBP,FOXG1,SELL,SH3GL2,GAS7,CCDC80,NLGN1,BCAS1,BCO1,SLC6A9,CGREF1,SCG3,DLL3,DDX25,SNAP25,SNCB,ATP1A3,DKK3,MYH7,FXYD6,NCAM1,NELL1,SEPT3,NFIA,ABCC8,GLS,GNAS,CACNA1E,DDR1,NRGN,SYT6,GRIA1,GPR88,TF,OPCML,TGFBR3,GUCY1A2,TJP1,KCNK10,CD81,PC,CDH10,DCLK1,ZNF384,PDE1A,PHKG1,NLGN3,NEGR1,TJP2,NECAB2,SPATA6,P2RY12,POU3F2,PPP3CB,FEZ1,MAPK10,HES5,KLK6,RIMS3,DPYSL5,PTAFR,PTCH1,CEP170,CSDE1,PTPRO,SV2A,KCNJ4,KCNJ11,ARNT2,KCNN3,OLIG1,KLRC2,ABI1,ATN1,GNE,RTN4,CRTAC1,NUP214,ST8SIA3,LMO1,SEZ6" Drug 4770_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.81E-11 2.86E-06 1.06E-07 1.16E-06 29 177 "DPF1,ADD3,TUBB4A,APC,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,CDK5R2,BTRC,TNS1,PIK3CD,DNAJC12,BEST1,KIAA0513,RIMS3,DNAJC6,KCND3,SRGAP3,TMCC2,TTLL7,EFNA3,RASGRP2" Drug ctd:D007649 Ketamine CTD 1.04E-10 3.37E-06 1.20E-07 1.32E-06 72 803 "MAP6,MAPT,TMEM74,MBP,RTKN,KCNIP2,NDRG2,RXRG,SORCS1,AGT,SCN4B,ASIC4,MOG,SFPQ,SLC1A2,SLC2A5,LRRC55,ARHGAP5,ASCL1,TAGLN3,BRINP2,ATP1A2,ATP1A3,NKX6-2,ADGRB2,GFAP,NCDN,SLCO1C1,ACSBG1,ZNF638,C1QC,KAZN,MMD2,NRGN,HAP1,GRIN1,GRM3,TF,USP2,MFSD2A,INA,HRH3,TPM4,PCSK2,ZMYND8,GPR37L1,CHRM1,PLEKHB1,ZBED5,TMEFF2,HPCA,GDAP1L1,MICAL1,FAT3,ACBD5,POU3F2,CRLS1,VCAN,PHACTR3,CMTM5,PRKCG,HES5,SYTL2,PHYHIP,PLPPR1,PYGM,RASGRF1,PAK5,CRTAC1,JMJD1C,TTLL7,SLC39A12" Drug ctd:C013418 bromfenacoum CTD 1.37E-10 4.45E-06 1.53E-07 1.68E-06 62 645 "ABAT,MAP6,ACLY,RTN3,SLC25A25,RTN1,FABP7,ERMN,AGT,MOG,SFPQ,SGIP1,ANK3,ANXA7,PKP4,SH3GL2,APBB1,APC,GAS7,ARFGAP2,SLC8A2,NAXD,SNCB,ATP1A3,ATP2B2,TNIK,CAB39,GAD2,ALDH1L1,GFAP,MLC1,KAZN,CAMSAP2,CNTN2,NUDT21,GRIA4,INA,TJP1,AIFM1,TNR,PADI2,LGI1,HNRNPK,HEPACAM,CCDC136,CNTN1,VCAN,CTNND1,CTNND2,FAM131B,DNAJC6,HP1BP3,ATG16L1,C12orf4,RAP1GAP,ABI1,RTN4,ZYG11B,RBM12,VWA5A,SLC4A10,EPB41L1" Drug CID000005657 NSC7524 Stitch 1.75E-10 5.70E-06 1.90E-07 2.08E-06 29 182 "ASIC1,ACHE,RYR1,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ASIC4,B3GAT1,ATP1A2,ATP1A3,PALLD,SCN3B,GAD2,NKX6-2,NODAL,CACNA1A,CACNA1E,NPPA,CACNB2,GRIK3,GRIK4,PDE1C,PDYN,ASIC3,CHRM1,CHRNB2,CACNG7" Drug ctd:D020245 p-Chloromercuribenzoic Acid CTD 3.27E-10 1.06E-05 3.43E-07 3.76E-06 77 909 "TTYH1,MAP6,ASIC1,TMEM74,CNTNAP3,SYT9,SLITRK1,ADCYAP1R1,LRRTM4,SEMA6A,SOX6,CDC42BPA,ANK1,USP28,PPFIA1,BCAN,CACHD1,SHTN1,SLC1A2,BCO1,LRRC55,PKNOX2,SMARCE1,TMEM108,PALLD,SOX1,SOX5,JPH4,SALL3,STARD10,NFASC,NCAM1,LMO3,COLGALT2,STOX1,SMOC1,GFRA1,AJAP1,GLS,CNTN2,WSCD1,GPM6B,CACNB2,DDR2,GRM3,GUCY1A2,KCNK10,PAX6,REPS2,PCDH8,HRH3,CCDC136,CELF5,PRRX1,FAT3,POU3F2,SNCAIP,FEZ1,NCAN,DOCK7,PLD5,CTNND2,HES5,ZBTB16,SPIRE1,ZNF385B,RGMA,MED24,OLFM3,RABGAP1L,CALN1,RET,RFX4,RGS7,SFXN5,LMO1,SEZ6" Drug ctd:C014024 "2,4,5,2',4',5'-hexachlorobiphenyl" CTD 4.25E-10 1.38E-05 4.31E-07 4.73E-06 127 1835 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,PLA2G6,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SLC8A3,SHANK2,CADPS,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,NFIA,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,GRM3,OMG,OPCML,TIE1,TJP1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,TUB,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,MAPK8,HES5,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,PTPRD,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug ctd:C035988 procymidone CTD 5.63E-10 1.83E-05 5.54E-07 6.08E-06 26 156 "MBP,LRRC7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,ASIC3,DLGAP3,CADM1,NRXN1,NRXN2,NCAN,MAGI2,DPP6,CACNG7" Drug 3087_UP Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.45E-10 2.09E-05 6.16E-07 6.75E-06 29 192 "MOBP,C1orf61,CDC42BPA,AQP4,DNAH17,PALLD,RAP1GAP2,ALDH1L1,NEUROD1,GNG4,GPM6B,PSD3,GRIA1,INA,NEURL1,KCNK10,PADI2,TNS1,PCDH9,PDE4B,MICAL2,EDRF1,DLG3,PID1,TMEM255A,NUP214,TTLL7,SSPN,ROM1" Drug CID000003816 NSC759587 Stitch 1.14E-09 3.70E-05 1.06E-06 1.16E-05 47 444 "ABAT,ACHE,ADAR,ADORA1,ADORA3,GAS7,SLC1A2,MSR1,SLC8A2,MT3,SNAP25,ATP2B2,SOX10,GAD2,BCL2L2,GFAP,GFRA1,SYT4,CACNB2,NRGN,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,OLR1,OMG,TNFRSF1B,PDYN,CHRM1,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PRDM2,KCNA1,PTPRZ1,DLG2,SLC17A6,EEF1A2,EPB41L1" Drug 4121_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-09 3.88E-05 1.08E-06 1.18E-05 29 197 "EMID1,SYNDIG1,DOCK10,GAS7,SLC2A5,PKNOX2,GPR153,ASPH,BRINP2,CCDC181,FYN,ATP2B2,NMNAT2,LMO3,GFAP,RND1,AJAP1,OPCML,CHI3L2,CHRNB2,CAMKV,FADS2,SDC3,NOS1AP,NTM,RAB3IL1,ATN1,RGS10,SSPN" Drug ctd:D008044 Linuron CTD 1.42E-09 4.62E-05 1.25E-06 1.37E-05 23 129 "LRRC7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,MAGI2,DPP6,CACNG7" Drug CID000005514 T2755 Stitch 1.83E-09 5.95E-05 1.57E-06 1.72E-05 17 71 "ABAT,ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,CA14,ASIC3,PTCH1" Drug CID000448294 AC1L9LT0 Stitch 3.03E-09 9.85E-05 2.53E-06 2.77E-05 22 123 "APC2,ANK1,ANK2,ANK3,APC,MAGI3,NKX6-2,BTRC,GRIA1,GRIA2,CRB1,TJP1,PCSK2,MAGI1,CADM1,TJP2,ARHGEF4,KCNA4,PARD6A,DLG2,DLG3,EPB41" Drug 413_UP trichostatin A; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 4.57E-09 1.48E-04 3.71E-06 4.07E-05 28 196 "ADD3,FHL1,PPM1E,SLC1A2,ZNF365,ALDH4A1,ATP1A2,FYN,TNIK,ZCCHC24,ZSWIM8,FXYD6,ACSBG1,GLS,BTRC,ATF7,CAMK2A,DDR2,GRIA4,GRIN1,TF,OPCML,DNAJC12,IFFO1,ARHGEF4,MAPK8,PTCH1,ABCC9" Drug 4239_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-09 1.67E-04 4.06E-06 4.45E-05 28 197 "ACTN2,RYR1,LRRTM4,MSR1,SLCO1A2,CCDC181,TNIK,NFASC,RND1,ACSBG1,MLC1,SEMA4A,GNG4,NPPA,GRIA1,TNS1,ARHGAP22,SLC22A6,ZFYVE9,CNTN1,CHD5,MAPK8,RIMS3,ITIH2,KCNA2,SRGAP3,ATN1,VWA5A" Drug 3827_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "NDRG2,RYR1,FOXRED2,KIAA1109,AQP4,SLN,ATP2B2,VAMP1,CACNA1A,GPR17,HAP1,GPR88,USP2,PTGDR2,PDE2A,CHI3L2,CNTN1,BEST1,NECAB2,SPATA6,CTNND2,PTAFR,MAGI2,KCND3,RASGRF1,ABCC9,VWA5A,LRRC23" Drug 2550_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "MAPT,SYNDIG1,NDRG2,LRRTM4,ANK1,ANK3,PKP4,AQP4,MSR1,PKNOX2,ASPH,ACSBG1,GLS,WSCD1,TGFBR3,PTGDR2,SCRG1,CHRNB2,PHKG1,FLRT1,PMP2,PKN2,CTNND2,MAPK8,EDRF1,KCNMA1,SEC61A2,SSPN" Drug 3797_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "ACTN2,ADORA3,AGT,C1orf61,AQP4,SLC1A6,PKNOX2,SLN,ATP2B2,CADM3,SOX10,ALDH1L1,CRB1,PADI2,TNS1,PTGDR2,CABP1,PROX1,PTAFR,PRDM2,MAGI2,SRGAP3,KCNJ4,ATN1,ABCC9,RET,LRRC23,RASGRP2" Drug ctd:C009618 "O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate" CTD 5.98E-09 1.94E-04 4.32E-06 4.73E-05 29 211 "ACHE,FGF14,SEMA6A,FOXG1,ANK3,NLGN1,CSPG5,ATP2B2,NFASC,NCAM1,NDUFA5,NKX2-2,SEMA4A,CNTN2,TF,INA,TNR,NLGN3,NRXN1,NRXN2,SEMA5B,CPT1C,RIMS4,NOS1AP,DPYSL5,TOMM20,RET,SH3GLB1,ELAVL3" Drug 3243_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.02E-09 2.28E-04 4.95E-06 5.43E-05 26 175 "ADD3,TUBB4A,SEMA6A,HPCAL4,PPM1E,SYBU,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,NAV2,EFNA3,VWA5A,RASGRP2" Drug DB00142 L-Glutamic Acid Drug Bank 7.20E-09 2.34E-04 4.98E-06 5.46E-05 16 68 "ABAT,FOLH1,SLC1A2,SLC1A6,SLC1A7,GAD2,GLS,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,SLC25A18" Drug ctd:C038939 enzacamene CTD 8.83E-09 2.87E-04 5.97E-06 6.55E-05 22 130 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug ctd:C069837 fullerene C60 CTD 1.88E-08 6.12E-04 1.25E-05 1.37E-04 104 1501 "SERPINA3,MAP6,ASIC1,ACHE,APC2,TMEM74,MBP,SLITRK1,ADORA1,FOXRED2,CHST15,HOGA1,PLA2G6,ASIC4,SOX6,RASA3,ITSN1,APBA2,GAS7,CACHD1,SYBU,ST3GAL3,SLC2A5,BCO1,YPEL4,SLC14A1,SCMH1,GPR153,DNAH17,SLN,B3GAT1,ALDH4A1,SNAP25,ZCCHC24,AHCYL1,LHFPL4,CPLX2,LMO3,GPR162,GJB1,ADHFE1,SEPT3,FAM168A,MLC1,ARHGEF7,C1QC,UNC5D,MMD2,WSCD1,CACNA1E,NPPA,B4GALNT4,NRGN,TMEM151B,NUCB1,AKNA,GRIN1,ATP13A2,OLR1,OPCML,USP2,MFSD2A,TIE1,ZFP91,PAX6,TNS1,DCLK1,PTGDR2,NTSR2,CHRM1,CHRM4,NLGN3,ZFYVE9,PIK3CD,UBTF,CCDC136,CELF5,IFFO1,TENM4,PRKACB,SDC3,CALY,ARHGEF4,NRSN1,HES5,PROX1,MASP1,ZBTB16,MED24,NTM,TMCC2,KCNN3,RAB3IL1,KLRC2,SLC17A6,ATG16L1,RASGRF1,CAMK1G,PHC2,TTLL7,EEF1A2,VANGL2,EFNA3,RASGRP2" Drug 3123_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-08 6.86E-04 1.37E-05 1.51E-04 27 197 "CEND1,ASIC4,CDC42BPA,AQP4,GPR153,PALLD,WDTC1,CPLX2,ALDH1L1,CACNB2,OMG,TJP1,TNS1,PDE1C,CHRM4,ATRNL1,EDRF1,SYNC,PMEPA1,ITIH2,TMCC2,DLG3,RGS10,TTLL7,ELAVL4,RCAN2,LRRC23" Drug CID000104810 barium Stitch 2.17E-08 7.06E-04 1.38E-05 1.52E-04 23 148 "ADORA1,ANXA7,MTR,CACNA1A,CACNA1E,NPPA,P2RX7,KCNK10,CHRM1,PRKCG,PKN2,PRKCZ,KCNA1,KCNA6,KCNC1,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3" Drug CID000005123 willardine Stitch 2.21E-08 7.18E-04 1.38E-05 1.52E-04 11 32 "FOLH1,ADHFE1,ABCC8,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,KCNA2" Drug 5625_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.41E-08 7.81E-04 1.45E-05 1.59E-04 25 173 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,USP2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,JAKMIP2,EFNA3" Drug CID000003779 isoproterenol Stitch 2.42E-08 7.85E-04 1.45E-05 1.59E-04 58 669 "ASIC1,ADAR,ADARB2,ADCY2,RYR1,ADORA1,ADORA3,TUBB4A,AGT,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,BBOX1,ANK2,AQP4,PDE8B,NRG3,SCN3B,MYH7,GFAP,NEUROD1,ABCC8,GNAS,CACNA1A,NPPA,CACNB2,AZIN2,TF,GUCY1A2,P2RX7,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,HPSE2,CHGA,ASIC3,CHRM1,P2RY12,VCAN,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,KLK6,TUBB2B,KCND3,KCNK1,PCDH15,KCNMA1,PYGM,ABCC9,LPAR6" Drug 6671_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.55E-08 8.28E-04 1.51E-05 1.65E-04 26 186 "ABAT,CEND1,SORBS1,TAGLN3,FYN,TNIK,ADGRB2,RGL1,RND1,GLS,CDK5R2,HAP1,USP2,TNS1,LILRA4,DNAJC12,VCAN,KIAA0513,DNAJC6,JAKMIP2,PLPPR4,SRGAP3,PID1,DSCAM,EFNA3,VWA5A" Drug ctd:D004390 Chlorpyrifos CTD 2.65E-08 8.59E-04 1.53E-05 1.68E-04 75 968 "MAG,ASIC1,ACHE,SYT9,SLITRK1,TESK2,AGT,FGF1,MOBP,MOG,CDC42BPA,SLC1A2,SLC1A6,SLC1A7,CGREF1,SCG3,SLIT1,ATM,DKK3,USP33,NCAM1,ERBIN,GFAP,FGF17,ADHFE1,NEUROD1,RND1,CNTN2,ZEB1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,USP2,TJP1,ZFP91,CD81,TNR,RBFOX2,PCSK2,PDE1C,PDE3B,PDYN,HMGB1,CHGA,PFKFB3,CHRM1,CHRM4,CHRNB2,HNRNPK,NEGR1,POU3F2,MED1,CHD5,PRKAB2,DZIP3,MAPK8,ZBTB16,RIMS3,CSDE1,DLG2,PYGM,RTN4,L1CAM,RET,ST8SIA3,VANGL2,ELAVL4,BAALC" Drug 4837_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.92E-08 9.49E-04 1.66E-05 1.83E-04 27 200 "ADORA3,C1orf61,APC,AQP4,TAGLN3,IGSF9B,SNAP25,SCN3B,NCAM1,ACSBG1,WSCD1,HAP1,PSD3,OPCML,HRH3,ADGRG1,CAMKV,CABP1,IFFO1,OSBPL3,NCAN,ITIH2,ATN1,DSCAM,USH1C,LRRC23,RASGRP2" Drug 5441_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.41E-08 1.11E-03 1.91E-05 2.10E-04 25 176 "DPF1,ADD3,TUBB4A,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,RGL1,ACSBG1,GLS,CDK5R2,USP2,SERPINE2,PIK3CD,DNAJC12,MAPK10,KIAA0513,DNAJC6,JAKMIP2,TMCC2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug ctd:C118580 octylmethoxycinnamate CTD 3.57E-08 1.16E-03 1.96E-05 2.15E-04 22 140 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug CID000166931 phosphine oxide Stitch 4.05E-08 1.32E-03 2.19E-05 2.40E-04 19 107 "MAG,MBP,RYR1,MOBP,MOG,KIF1B,GJB1,MLC1,OMG,PC,PRKACB,PRKCG,PKN2,PRKCZ,KCNC1,KCNJ10,KCNMA1,KCNQ2,ROM1" Drug CID006437089 PbTx-1 Stitch 4.28E-08 1.39E-03 2.26E-05 2.48E-04 10 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,GABBR1,SCN3B,GJB1,ASIC3,KCNA2" Drug CID000003538 GYKI 52466 Stitch 4.43E-08 1.44E-03 2.26E-05 2.48E-04 14 58 "SLC1A2,BCO1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,MAPK10,PTCH1,ABCC9,NUP214" Drug ctd:D006220 Haloperidol CTD 4.45E-08 1.45E-03 2.26E-05 2.48E-04 37 344 "DPF1,MAG,SERPINA3,MBP,RXRG,HPCAL4,MOG,SLC1A2,SNAP25,ATP1A3,FYN,TNIK,GAD2,VAMP1,SYT4,GNAS,CACNA1A,NPPA,CAMK2A,GRIA1,GRIA2,GRIK2,GRIK4,GRIN1,TF,CDC42,DCLK1,CHRM4,NCAN,PRKACB,PRKCZ,MAPK8,WBP1L,KCNA1,SLC17A6,RASGRF1,RTN4" Drug CID000000681 dopamine Stitch 4.45E-08 1.45E-03 2.26E-05 2.48E-04 60 715 "ABAT,ACHE,CLIP1,ADCY2,RYR1,ADORA1,ADORA3,AGT,FGF14,ACTL6B,FOXM1,SLC1A2,SNAP25,SNCB,ATP1A3,FYN,SOX10,GAD2,ARPP21,NPAS3,NDUFA5,GFAP,GFRA1,ADHFE1,GNAS,CACNA1A,CACNA1E,NPPA,PRLHR,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,GUCY1A2,PAH,HRH3,PDE3B,PDYN,NTSR2,CHRM1,CHRNB2,PTPA,CALY,PRKCG,PKN2,PRKCZ,KCNA6,KCNJ4,KCNJ9,KCNJ10,SLC17A6,SLC6A15,RET,RGS10,EEF1A2,EN2" Drug CID000003150 AC1L1FA8 Stitch 5.15E-08 1.67E-03 2.57E-05 2.82E-04 13 50 "ADCY2,SLC1A2,SOX10,GFAP,NUCB1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" Drug CID000001065 quindine Stitch 5.34E-08 1.73E-03 2.63E-05 2.88E-04 28 219 "ASIC1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SHANK2,SLC14A1,SLCO1A2,SCN3B,CACNB2,KCNK10,ASIC3,CHRM1,CHRNB2,SULT4A1,DPYSL5,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNK1,KCNK2,KCNMA1,KCNN3" Drug 4098_UP Furazolidone [67-45-8]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.78E-08 2.20E-03 3.29E-05 3.60E-04 26 195 "MAPT,AGT,BBOX1,APC,NTNG1,GAS7,RPH3A,PKNOX2,ASCL1,ATP1A2,FGF17,KLHL4,GRIN1,TF,SPX,GUCY1A2,CDH10,HPCA,CADM1,ST8SIA5,CTNND2,NOS1AP,PHYHIP,KCNJ10,FAM13C,RASGRP2" Drug CID000003763 isoflurane Stitch 8.22E-08 2.67E-03 3.93E-05 4.31E-04 32 279 "MAG,ASIC1,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,ATP2B2,SCN3B,VAMP1,NODAL,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,LEFTY2,KCNK10,TPM3,ASIC3,CHRM1,CHRNB2,NSD2,PRKCG,KCNA1,KCNK2,KCNMA1,ABCC9" Drug 4421_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.35E-08 2.71E-03 3.93E-05 4.31E-04 26 197 "DPF1,MAG,ASIC1,NDRG2,KIAA1109,FHL1,RASA3,GAS7,SLC14A1,ATP2B2,ADAM15,ALDH1L1,GNAS,GNG3,ATF7,GRIN1,TPM3,PDE3B,ASIC3,PACSIN1,SNCAIP,RGS6,MAPK8,PARP11,VWA5A,RASGRP2" Drug 1529_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.25E-08 3.01E-03 4.29E-05 4.71E-04 26 198 "RYR1,ADORA1,KIAA1109,ITSN1,BCAN,SYBU,GPR153,ATM,ATP1A3,INKA2,GLS,GPM6A,NPPA,CDH8,PCSK2,PDE1C,GPR37L1,FADS2,PACSIN1,MED1,SNCAIP,SYNC,MAGI2,RAD52,ATN1,VWA5A" Drug CID000000923 sodium Stitch 9.45E-08 3.07E-03 4.33E-05 4.74E-04 72 944 "ASIC1,ADAR,F3,ADCY2,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,ASRGL1,ANK2,ANK3,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC2A5,SLC6A9,SLC8A2,SLC8A3,SLCO1A2,MTR,ATP1A2,ATP1A3,ATP2B2,SCN3B,NKX6-2,GART,DNER,GLS,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,INA,P2RX7,TJP1,TPM3,ASIC3,CHRNB2,SLC22A6,CP,KCNT2,PRKACB,PRKCG,PKN2,PRKCZ,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,DLG3,SLC17A6,SLC6A15,UEVLD" Drug 5906_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "KCNIP2,ADCY2,FGR,SLC1A7,TNIK,ZCCHC24,CADM3,NMNAT2,CPLX2,COLGALT2,PHLDB1,RND1,AJAP1,HAP1,TMEM151B,OPCML,CCKBR,KCNK10,TMPRSS5,PIK3CD,SULT4A1,CNTN1,RIMS3,KCNJ4,ELAVL3,RASGRP2" Drug 3614_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "APC2,GRAMD1B,PLA2G6,FHL1,AMPH,RASA3,SLC6A9,SHANK2,ATP1A2,ATP2B2,NMNAT2,ALDH1L1,PHLDB1,POPDC3,ROBO3,CACNA1A,USP2,PKN2,RIMS3,PTAFR,SV2A,SRGAP3,RAB3IL1,DNAH9,RAD52,NUP214" Drug 3546_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "ADCY2,RYR1,SEMA6A,FOXG1,RPH3A,BCO1,MSR1,PKNOX2,GPR153,SORCS3,ATP1A3,WDTC1,ZSWIM8,AJAP1,GNG3,WSCD1,GPM6A,GPM6B,ATF7,TCF7L2,OLR1,PLCH2,MAGI2,KCND3,TMEM255A,RASGRP2" Drug 2728_UP Butacaine [149-16-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ABAT,MAPT,TUBB4A,PLA2G6,AMPH,APBA2,SLC1A7,ASCL1,TAGLN3,ATP1A3,PALLD,CADM3,GAD2,ROBO3,GRIK2,USP2,PDE1C,HPSE2,ZFYVE9,CAMKV,FLRT1,VAV2,POU3F2,KCNC1,FAM13C,RASGRP2" Drug 6405_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ARID1A,NDRG2,HPCAL4,APBA2,APC,BCAS1,SLC1A7,BCO1,CGREF1,ATP1A3,GAD2,INKA2,PHLDB1,GLS,WSCD1,NPPA,ZEB1,USP2,ASIC3,ZFYVE9,SULT4A1,SPATA6,VCAN,SDC3,MAPK8,USH1C" Drug 6181_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ACTN2,TUBB4A,FHL1,BCAS1,MSR1,SHANK2,GPR153,TAGLN3,ASTN1,PALLD,MYBPC1,CADM3,ADGRL3,GRIK2,CRB1,GUCY1A2,CELF3,PTGDR2,HPCA,NCAN,PROX1,PRDM2,SMG7,SV2A,KCNK1,EFNA3" Drug CID000003019 diazoxide Stitch 1.15E-07 3.74E-03 4.80E-05 5.26E-04 28 227 "TUBB4A,FOXM1,GART,ABCC8,NPPA,GRIA1,GRIA2,GRIA4,GRM3,KCNK10,KCNT2,PRKCG,TUBB2B,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNMA1,KCNN3,KCNQ2,ABCC9" Drug CID000002910 cyclothiazide Stitch 1.18E-07 3.84E-03 4.86E-05 5.33E-04 18 103 "MBP,SLC1A2,SLC1A6,SLC8A2,GFAP,CACNA1A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,SLC22A6,NCAN,PTPRZ1,KCNMA1" Drug 2268_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.26E-07 4.08E-03 5.11E-05 5.60E-04 24 175 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,ZNF365,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,WSCD1,USP2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3,RASGRP2" Drug CID000038945 tocainide Stitch 1.37E-07 4.44E-03 5.48E-05 6.01E-04 10 30 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ANK2,SCN3B,ACOT7,ASIC3,KCNA4" Drug ctd:C010902 decabromobiphenyl ether CTD 1.39E-07 4.53E-03 5.52E-05 6.06E-04 105 1582 "RIMKLA,MAPT,ACHE,DUSP27,RYR1,HHATL,TOMM40L,SCN3A,SCN4B,PLA2G6,FGF14,BBOX1,CDC42BPA,ANK1,USP28,ITSN1,GPAM,CACHD1,ST8SIA1,AQP4,SLC6A9,ASCL1,ASTN1,RCOR3,SNAP25,TMEM151A,SNCB,GABBR1,ZCCHC24,ILDR2,MYH7,ARPP21,TTLL9,STARD10,NFASC,BCL2L2,RCOR2,SLCO1C1,FAM168A,MLC1,ZNF638,DCLK2,GNG3,CDK5R2,TMEM136,TBX15,GPM6B,DDR1,CACNB2,CAMK2A,GRIK3,CCKBR,SPX,USP2,GUCY1A2,PAH,CDK11B,PAX6,TNR,PCDH8,DCLK1,RBFOX2,TPM4,PDE1A,PDYN,TUB,CHRNB2,NLGN3,DLGAP3,ANLN,UBTF,CPT1C,A2ML1,ST8SIA5,FAM181B,PRRX1,PNKD,VCAN,RBPJ,PRKAB2,PRKACB,DZIP3,SDC3,PKN2,MAPK8,SPIRE1,PTCH1,KCNA4,PLPPR4,KCND3,KCNJ10,ARNT2,KCNMA1,NAV2,KCNN3,DLG2,PYGM,PLEKHB2,RET,RFX4,RFX5,VANGL2,OLIG2,PRRT4,RCAN2" Drug CID000003878 lamotrigine Stitch 1.54E-07 5.01E-03 5.97E-05 6.55E-04 19 116 "ABAT,ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,PTPN5,ASIC3,PTCH1,CACNG7" Drug ctd:D003024 Clozapine CTD 1.56E-07 5.06E-03 5.97E-05 6.55E-04 39 392 "DPF1,SERPINA3,MBP,RXRG,AGT,HPCAL4,MOBP,SLC1A2,SNAP25,GABBR1,TNIK,GAD2,CPLX2,GFAP,VAMP1,SYT4,GNAS,CACNA1A,CAMK2A,GRIA1,GRIA2,GRIK2,GRIN1,CCKBR,DCLK1,PDE4B,CHGA,CHRM1,SERPINE2,NCAN,PRKACB,PRKCZ,WBP1L,KCNA1,KCNK2,SLC17A6,RASGRF1,RTN4,RGS7" Drug 4821_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.56E-07 5.07E-03 5.97E-05 6.55E-04 24 177 "ADD3,TUBB4A,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,CDK5R2,TGFBR3,USP2,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,VWA5A,RASGRP2" Drug 6454_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.74E-07 5.65E-03 6.49E-05 7.12E-04 24 178 "DPF1,ADD3,TUBB4A,C1orf61,PPM1E,SORBS1,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,POPDC3,CDK5R2,WSCD1,TNS1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 4388_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.74E-07 5.65E-03 6.49E-05 7.12E-04 24 178 "DPF1,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,NMNAT2,RGL1,RND1,ACSBG1,GLS,CDK5R2,TGFBR3,PIK3CD,DNAJC12,KIAA0513,PTAFR,DNAJC6,TMCC2,EFNA3,VWA5A,RASGRP2" Drug CID000002520 verapamil Stitch 1.82E-07 5.92E-03 6.73E-05 7.38E-04 45 490 "ASIC1,ADCY2,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SLCO1A2,ATP1A2,ATP1A3,ATP2B2,SCN3B,MYH7,NODAL,CACNA1A,CACNA1E,NPPA,CACNB2,LEFTY2,KCNK10,HPSE2,ASIC3,CHRM1,CHRNB2,KCNT2,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNMA1,KCNN3,KCNQ2,ABCC9,CACNG7" Drug 2523_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.12E-07 6.90E-03 7.75E-05 8.50E-04 25 193 "EMID1,NDRG2,KIAA1109,CDC42BPA,PPM1E,ALDH4A1,CCDC181,FXYD6,NCAM1,RGL1,GNG4,PCDH9,PTGDR2,PHKG1,ZFYVE9,KIAA1549L,NMT2,CCSER2,FEZ1,DZIP3,RIMS3,DNAJC6,USH1C,EFNA3,VWA5A" Drug 4349_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.39E-07 7.75E-03 8.58E-05 9.40E-04 24 181 "ADD3,TUBB4A,HPCAL4,PPM1E,ZNF365,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,USP2,TNS1,PDE1C,SERPINE2,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,ST8SIA3,TTLL7,VWA5A,RASGRP2" Drug ctd:D010622 Phencyclidine CTD 2.43E-07 7.88E-03 8.58E-05 9.40E-04 16 86 "MBP,MOBP,GABBR1,GAD2,CPLX2,GFAP,GNAS,CAMK2A,GRIA4,GRIN1,CCKBR,PRKCG,KCNH1,KCNJ4,SLC17A6,RTN4" Drug ctd:D000431 Ethanol CTD 2.43E-07 7.89E-03 8.58E-05 9.40E-04 106 1620 "ABAT,ACHE,ACLY,MBP,SYT9,F3,ADCY2,RXRG,ADCYAP1R1,FABP7,ADORA1,TUBB4A,AGT,FGF1,AMPH,NTNG1,GPAM,BCAS1,AQP4,SLC1A2,SLC1A6,RPH3A,SLC6A9,ARHGAP5,SLC8A3,MT3,SCG3,MTR,ADGRA1,SNAP25,ATM,FYN,ATP2B2,MYT1L,ILDR2,ARPP21,ALDH1L1,NDUFA5,GFAP,GFRA1,PHLDB1,VAMP1,GNG3,MMD2,NPPA,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,GPR88,GRM3,TF,OPCML,TJP1,AIFM1,CDK11B,CDC42,PDE3B,PDE4B,PDYN,HMGB1,HNRNPK,HPCA,SERPINE2,CADM1,OPALIN,FADS2,DNAJC12,CCDC136,PMS2,PPP3CB,PRKACB,FMN2,CMTM5,PRKCG,PRKCZ,IGSF1,MAPK8,ZBTB16,DPYSL5,TUBB2B,PTCH1,PTHLH,KCNA1,PTPRO,NTM,AK5,KCNMA1,NKAIN1,DNM2,SLC17A6,SLC25A18,ATN1,DTNA,L1CAM,RET,ST8SIA3,PLEKHO1,RASGRP2" Drug 7237_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-07 8.42E-03 9.06E-05 9.93E-04 25 195 "ADORA1,KIAA1109,PLA2G6,ANK1,GAS7,CCDC88A,ATM,AJAP1,VAMP1,POPDC3,BTRC,PSD3,OMG,USP2,NEURL1,CHD5,SDC3,ARHGEF4,PROX1,KCNC1,KCND3,KIF2A,RASGRF1,SSPN,EFNA3" Drug CID000003446 gabapentin Stitch 2.64E-07 8.56E-03 9.11E-05 9.99E-04 23 169 "ABAT,ASIC1,RYR1,ADORA1,SCN3A,SCN4B,SCNN1D,ASIC4,FOXG1,SCN3B,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,ASIC3,ETNPPL,CACNG7" Drug ctd:D003561 Cytarabine CTD 2.84E-07 9.22E-03 9.68E-05 1.06E-03 51 598 "TTYH1,NDRG2,RTN1,FABP7,DISP3,BCAR3,SGIP1,CNIH2,NTNG1,SLITRK3,SLN,FYN,PHYHIPL,RGL1,GLS,ROBO3,PSRC1,GPM6A,GPR19,TCF12,DDR2,PSD3,GRIA2,OLR1,CCKBR,TGFBR3,INA,GUCY1A1,CELF3,PAX6,MAGI1,PDE1A,PDE4B,JAM2,SEMA5B,PRKCZ,HES5,KLK6,SYTL2,STMN4,PARD6A,PTPRZ1,SRGAP3,NTM,NAV2,CAB39L,RAB5B,SLC17A6,ATN1,ATL1,BSCL2" Drug 2681_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.86E-07 9.30E-03 9.68E-05 1.06E-03 25 196 "ACTN2,MDM4,RTN1,ADCY2,HPCAL4,MOBP,FOXG1,SLC8A2,TAGLN3,ATP2B2,MYRF,GRIK2,GRIN1,OMG,CDH10,GPR37L1,HPSE2,CHI3L2,PHKG1,CCSER2,ATN1,CAMK1G,USH1C,EFNA3,LPAR6" Drug CID006324635 LY339434 Stitch 2.94E-07 9.56E-03 9.75E-05 1.07E-03 6 9 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4" Drug CID005311255 Ly294486 Stitch 2.94E-07 9.56E-03 9.75E-05 1.07E-03 6 9 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 7037_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.16E-07 1.03E-02 1.02E-04 1.12E-03 25 197 "MAPT,NDRG2,FOXG1,CDC42BPA,ITSN1,BCAS1,SHANK2,SPART,ARHGEF7,GNG4,TCF7L2,NUMA1,CDH10,UBTF,DZIP3,CTNND1,EDRF1,RIMS3,PRDM2,PARD6A,NKAIN1,RAD52,DTNA,EFNA3,RBM12" Drug 2401_UP Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.16E-07 1.03E-02 1.02E-04 1.12E-03 25 197 "MDM4,ADORA1,TUBB4A,DOCK10,BCAS1,AQP4,GPR153,ASPH,ALDH4A1,ATP2B2,AJAP1,TCF7L2,NUMA1,PSD3,OLR1,TPM3,COL9A2,PRKCZ,MAPK8,KLK6,ITIH2,PTPRD,KCND3,ATN1,DSCAM" Drug ctd:C038091 butylparaben CTD 3.19E-07 1.04E-02 1.02E-04 1.12E-03 22 158 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug CID000001207 MK-801 Stitch 3.20E-07 1.04E-02 1.02E-04 1.12E-03 32 296 "ACHE,ADORA1,ADORA3,FOXM1,FOLH1,SLC1A2,B3GAT1,SOX10,GAD2,NPAS3,NCAM1,GFAP,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,PDE2A,PDE4B,PDYN,NTSR2,CHRM1,CHRNB2,PRKCG,CTNND2,PTCH1,EEF1A2,OLIG2" Drug 7535_DN irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.27E-07 1.06E-02 1.03E-04 1.13E-03 23 171 "MBP,LGR4,GRAMD1B,CHST15,BCAR3,ITSN1,TACC2,CAB39,ERBIN,ARHGEF7,CAMSAP2,WWC1,TCF7L2,ZEB1,TCF12,PDE1C,CCSER2,TENM4,OSBPL3,PKN2,PUM1,NAV2,ZNF248" Drug 3781_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "MDM4,KCNIP2,NDRG2,FABP7,AMPH,RASA3,GAS7,PDE8B,ATP1A2,NFASC,PHLDB1,VAMP1,SEMA4A,NPPA,GPR17,GRIA4,GRIN1,PDE4B,CHI3L2,PIK3CD,VAV2,PMP2,PRDM2,RAB3IL1,ATN1" Drug 4375_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "EMID1,AGT,FOXG1,CCDC88A,TAGLN3,ASPH,MYBPC1,KIF21B,SPART,NCAM1,AJAP1,FAM168A,GPM6B,OPCML,GUCY1A2,HRH3,CHI3L2,PIK3CD,CNTN1,POU3F4,PTHLH,STMN4,RAD52,ATN1,DTNA" Drug 4351_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "DPF1,MAPT,APC2,MBP,SLC14A1,SLCO1A2,TAGLN3,SCN3B,MLC1,CCKBR,SEZ6L,CHI3L2,PIK3CD,SULT4A1,CNTN1,MICAL2,NOS1AP,MASP1,PHYHIP,PTHLH,KCNMA1,PEX5,RGS7,LMO1,EN2" Drug 3568_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "C1orf61,APBA2,ALDH4A1,CCDC181,FYN,GAD2,LMO3,FGF17,PHLDB1,RND1,SLCO1C1,CAMK2G,GRM3,KCNK10,CDH8,PTGDR2,HPCA,SNCAIP,RIMS3,SLC17A6,PARP11,ATN1,NUP214,USH1C,EFNA3" Drug 4525_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "EMID1,RTN1,FOXRED2,AGT,FGF1,RASA3,PKNOX2,ADGRB2,NEUROD1,VAMP1,KAZN,ADGRL3,PRUNE2,SPX,TLL2,SEZ6L,PDE3B,IFFO1,RGS6,VCAN,KCNMA1,ATN1,RASGRF1,FAM13C,NUP214" Drug 4428_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "ACTN2,NDRG2,FABP7,PDE8B,ATP2B2,SOX10,RND1,CDK5R2,KLHL4,CACNA1A,CAMK2A,GRIK2,ADAMTS8,NEURL1,ZMYND8,HPSE2,CHRNB2,VAV2,CTNND2,MAPK8,EDRF1,SUSD4,RASGRF1,RGS10,RASGRP2" Drug 5935_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.60E-07 1.17E-02 1.06E-04 1.16E-03 24 185 "ADD3,TUBB4A,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,CACNB2,ZEB1,PCDH9,PIK3CD,DNAJC12,SRGAP3,TMCC2,TTLL7,EFNA3,VWA5A" Drug CID000000806 "D-myo-inositol-1,4,5-triphosphate" Stitch 3.65E-07 1.19E-02 1.07E-04 1.17E-03 49 569 "MRVI1,ADCY2,RYR1,ADORA1,ADORA3,AGT,FGF1,ACTL6B,FOXM1,ANK2,ANK3,RASA3,ANXA7,DGKZ,DGKD,SLC8A3,B3GAT1,ATP1A2,ATP1A3,FYN,ATP2B2,AHCYL1,NEUROD1,CACNA1A,CACNA1E,NPPA,CACNB2,HAP1,GRM3,CCKBR,HRH3,ACOT7,CHGA,CHRM1,CABP1,PPP3CB,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PLPPR5,PTAFR,KCNMA1,PYGM,CACNG7,EN2,EPB41L1" Drug CID000003025 dibucaine Stitch 3.72E-07 1.21E-02 1.07E-04 1.18E-03 14 68 "ASIC1,ACHE,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,TF,ASIC3,CP,PLPPR5,CALN1,SLC25A18,PHC2" Drug 5081_UP Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "KCNIP2,NDRG2,MOBP,BCAN,AQP4,ATP1A3,ATP2B2,NEUROD1,VAMP1,KAZN,GNG4,OPCML,SEZ6L,PDE4B,GPR37L1,RGS6,VCAN,MAPK10,KCND3,ATN1,RASGRF1,FAM13C,DTNA,CAMK1G,ST8SIA3" Drug 3609_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "RYR1,KIAA1109,SLC30A10,GAS7,TAGLN3,DDX25,GAD2,NPAS3,COLGALT2,GFAP,ACSBG1,ROBO3,WSCD1,OPCML,PACSIN1,POU3F4,ETNPPL,RIMS3,ELMO1,PARD6A,SRGAP3,RAD52,CRTAC1,VWA5A,EN2" Drug 7226_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "APBA2,AQP4,SLN,ASTN1,ATP1A2,CADM3,ALDH1L1,MLC1,GNAS,GNG3,PRUNE2,WSCD1,PAH,DAAM2,TNS1,PTGDR2,PHKG1,ZFYVE9,SDC3,ARHGEF4,BEND5,SSPN,EFNA3,LMO1,RASGRP2" Drug 3260_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "ARID1A,FOXRED2,PLA2G6,SEMA6A,CDC42BPA,ANK3,ATP1A2,CPLX2,INKA2,RND1,VAMP1,POPDC3,NPPA,ZEB1,NUMA1,NEURL1,PDE3B,CHRNB2,SULT4A1,RIMS3,PTAFR,RAB3IL1,DTNA,VWA5A,ELAVL3" Drug CID000449524 IN-1 Stitch 3.90E-07 1.27E-02 1.08E-04 1.19E-03 11 41 "MAG,MBP,RTN3,RTN1,FGF1,MOBP,MOG,OMG,TNR,RTN4,EN2" Drug 3131_UP Scopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.22E-07 1.37E-02 1.16E-04 1.27E-03 25 200 "PLA2G6,HPCAL4,FOXG1,AMPH,ANK3,AQP4,GPR153,ALDH1L1,ACSBG1,WWC1,PRUNE2,PSD3,GRIK2,GRIN1,OMG,TJP1,DAAM2,CAMKV,SULT4A1,CTNND2,KCND3,TTLL7,SIDT2,ELAVL3,ROM1" Drug ctd:D007657 Ketone Bodies CTD 4.36E-07 1.42E-02 1.19E-04 1.31E-03 46 522 "MBP,CEND1,ARID1A,PLEKHG5,ADCY2,RXRG,GRAMD1B,FGF14,ANK3,PKP4,DGKZ,GPAM,BCAN,SCG3,ATP1A2,TNIK,ARPP21,TTC9B,CPLX2,NASP,CLASP2,GFRA1,ZNF638,NRGN,CAMK2A,SYT6,GRIA2,GRIK4,PTPN5,P2RX7,PADI2,PCSK2,ACOT7,CADM1,MEAF6,CELF5,CRMP1,CALY,PLPP4,NOS1AP,PSD,TOMM20,KCNJ9,SLC17A6,RTN4,RGS7" Drug 5572_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.48E-07 1.45E-02 1.21E-04 1.33E-03 23 174 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,USP2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3,VWA5A" Drug 2835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.96E-07 1.61E-02 1.32E-04 1.45E-03 23 175 "DPF1,ADD3,TUBB4A,PPM1E,SYBU,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,TGFBR3,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug 5417_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.96E-07 1.61E-02 1.32E-04 1.45E-03 23 175 "ADD3,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,ZEB1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,TMCC2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug CID000002474 bupivacaine Stitch 5.13E-07 1.67E-02 1.35E-04 1.48E-03 19 125 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,AQP4,SCN3B,MYBPC1,KCNK10,ASIC3,UBTF,HPR,PRKCG,PKN2,PRKCZ,KCND3,KCNK1,KCNK2,KCNQ2" Drug CID009543520 triphosphoinositide Stitch 5.24E-07 1.70E-02 1.37E-04 1.51E-03 30 273 "ASIC1,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,ANK1,DGKZ,DGKD,ARFGAP1,SCN3B,CDC42,ASIC3,CHRM1,PIK3CD,SDC3,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ9,KCNJ10,KCNK2,KCNQ2,EPB41,EPB41L1,EPB41L2" Drug CID006918393 YM928 Stitch 5.70E-07 1.85E-02 1.48E-04 1.62E-03 5 6 "GRIA1,GRIA2,GRIA4,GRM3,PTCH1" Drug CID000002351 bepridil Stitch 5.81E-07 1.89E-02 1.50E-04 1.64E-03 19 126 "ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC8A2,SLC8A3,SHANK2,ATP2B2,SCN3B,CACNA1A,CACNA1E,CACNB2,ASIC3,CHRM1,KCND3,CALN1,CACNG7" Drug 1835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.90E-07 1.92E-02 1.51E-04 1.65E-03 24 190 "EPS8,EYA1,WLS,NDRG2,ADD3,TESK2,ITSN1,CAPRIN2,ALDH4A1,PALLD,NCAM1,RGL1,CAMSAP2,GPR19,NRGN,ATP13A2,PADI2,DNAJC12,FEZ1,RIMS3,PTCH1,DNAJC6,EFNA3,EPB41L2" Drug 3993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.09E-07 1.98E-02 1.53E-04 1.68E-03 23 177 "ABAT,TESK2,SORBS1,TAGLN3,BRINP2,FYN,TNIK,ZCCHC24,RGL1,RND1,GLS,VAMP1,TNS1,PCDH9,DNAJC12,FEZ1,KIAA0513,PTCH1,DNAJC6,PLPPR4,SRGAP3,EFNA3,RASGRP2" Drug 4768_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.09E-07 1.98E-02 1.53E-04 1.68E-03 23 177 "DPF1,ADD3,TUBB4A,FHL1,HPCAL4,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,TNS1,SERPINE2,PIK3CD,DNAJC12,DZIP3,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug CID000003689 ifenprodil Stitch 6.50E-07 2.11E-02 1.62E-04 1.78E-03 14 71 "ADGRV1,ADORA1,AQP4,FYN,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,PDYN,RASGRF1" Drug CID000005114 3-(1H-pyrrole-2-carboxylate Stitch 6.80E-07 2.21E-02 1.69E-04 1.85E-03 27 233 "MAG,RYR1,ANK2,SLC8A2,SNAP25,ATP2B2,MYBPC1,WDTC1,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,GUCY1A2,CHRM1,CAMKV,CABP1,PRKACB,PRKCG,KCND3,KCNMA1,KCNN3,CAMK1G,NUP214" Drug ctd:D015655 1-Methyl-4-phenylpyridinium CTD 7.56E-07 2.46E-02 1.86E-04 2.04E-03 106 1659 "EPS8,RPL38,MAPT,ACHE,MEG3,WLS,SLITRK1,RYR1,ADORA1,TUBB4A,AGT,SCN3A,SFPQ,APC,SORBS1,AQP4,SFMBT2,SLC6A9,NAXD,SMARCE1,SNCB,ATP2B2,DKK3,B3GALT2,ARPP21,SALL3,STARD10,GART,ADGRB2,DNER,NASP,NFASC,LMO3,COLGALT2,BCL2L2,GFAP,FGF17,RND1,ABCC8,PCDH11X,NHLH1,ROBO3,UNC5D,KLHL4,WSCD1,TCF7L2,GPR19,DIRAS1,NRGN,NUDT21,DDR2,SYT6,VSTM2A,AKNA,GRIA2,RFFL,ATP13A2,AIFM1,KCNK10,TNFRSF1B,CDC42,IGSF21,PADI2,TNS1,PCDH9,CDH10,DCLK1,RBFOX2,MAGI1,CHGA,ZBED5,TMEFF2,SLC22A6,GDAP1L1,NEGR1,FAM181B,SLC25A27,COL9A2,CP,POU3F2,KCNT2,VCAN,CTNND1,MAPK8,MAPK10,PSD,RIMS3,PHYHIP,SIRPA,PLPPR1,JAKMIP2,SHD,MAGI2,PTPRO,KCNJ4,KCNJ11,RAB5B,FAM13C,RTN4,SLC6A15,RET,EEF1A2,ELAVL3,ELAVL4,EN2,SEZ6" Drug CID000001299 AC1L1B62 Stitch 7.76E-07 2.52E-02 1.90E-04 2.08E-03 8 21 "F3,FOLH1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 2247_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-07 2.67E-02 1.98E-04 2.17E-03 23 180 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,PTAFR,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 2639_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-07 2.67E-02 1.98E-04 2.17E-03 23 180 "ARID1A,ADD3,TUBB4A,PPM1E,ZNF365,ALDH4A1,FYN,ZCCHC24,NPAS3,ALDH1L1,RGL1,RND1,ACSBG1,GLS,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,KCNA1,TMCC2,GNE" Drug CID000161645 oriens Stitch 8.36E-07 2.72E-02 2.00E-04 2.19E-03 21 154 "ACHE,ADORA1,BCAN,SLC8A2,SNAP25,GAD2,GFAP,GRIA1,GRIA2,GRIA4,GRIK4,GRM3,CHRM1,NCAN,PRKCG,KCNA6,KCNC1,PTPRZ1,KCNJ9,NUP214,RGS7" Drug CID000001221 "R,S)-AMPA" Stitch 9.30E-07 3.02E-02 2.21E-04 2.42E-03 10 36 "AMPH,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TUB,NTM" Drug 3812_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-07 3.08E-02 2.22E-04 2.43E-03 24 195 "DPF1,CEND1,NLGN4X,APC,SLITRK3,SLC1A6,SLC2A5,PKNOX2,SLCO1A2,ATP1A2,ATP2B2,SLCO1C1,GRM3,GUCY1A2,PDE2A,CA14,SULT4A1,VAV2,PROX1,SMG7,NTM,ATN1,RASGRF1,ST8SIA3" Drug 3078_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.49E-07 3.08E-02 2.22E-04 2.43E-03 24 195 "CDHR1,ADORA1,HPCAL4,MOBP,ANK1,ANK3,APBA2,TAGLN3,SLN,NCAM1,ASTN2,GPM6B,NEURL1,TNS1,NRXN2,SULT4A1,ARHGEF4,CTNND1,STMN4,SMG7,RAD52,DSCAM,USH1C,ELAVL3" Drug CID000001248 AC1L1B1W Stitch 9.95E-07 3.23E-02 2.31E-04 2.53E-03 15 84 "ABAT,ADORA1,CSPG5,GAD2,ZEB1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,SULT4A1,BLOC1S6,DTNA,LRRC23" Drug 4773_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-06 3.38E-02 2.37E-04 2.60E-03 24 196 "FGF1,FGR,CDC42BPA,ATP1A2,COLGALT2,ALDH1L1,BTRC,WSCD1,GRM3,CELF3,SEZ6L,FADS2,CNTN1,IFFO1,POU3F4,NOS1AP,PHYHIP,ITIH2,PRDM2,KCND3,KCNJ9,KCNMA1,EFNA3,VWA5A" Drug 4461_UP fluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-06 3.38E-02 2.37E-04 2.60E-03 24 196 "MOBP,FOXG1,SLN,BRINP2,GAD2,ALDH1L1,RND1,CDK5R2,NPPA,GRIN1,INA,PAH,LILRA4,PDE4B,BEST1,NECAB2,EDRF1,TOX,SYNC,SRGAP3,RAD52,RASGRF1,DTNA,VWA5A" Drug ctd:D059808 Polyphenols CTD 1.04E-06 3.39E-02 2.37E-04 2.60E-03 41 455 "SERPINA3,CDHR1,ASIC4,FGR,HPCAL4,SELL,SH3GL2,GAS7,AQP4,SHANK2,CADPS,SCG3,DDX25,ATP1A3,SEPT3,SLCO1C1,GLS,GPR26,GRIN1,OLR1,CD81,CDC42,TPM3,PDE3B,PFKFB3,HPCA,CAMKV,CABP1,SLC25A27,NECAB2,POU3F2,PTPA,PPP3CB,NOS1AP,PTCH1,CEP170,KCNA2,KCNA4,SLC17A6,NUP214,RGS7" Drug CID000065749 13-methoxyibogamine Stitch 1.06E-06 3.46E-02 2.39E-04 2.62E-03 12 54 "FOXM1,SOX10,GFAP,CACNA1E,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,RET" Drug ctd:D004397 Fonofos CTD 1.11E-06 3.60E-02 2.39E-04 2.62E-03 56 714 "EPS8,RIMKLA,CDHR1,MBP,ADCY2,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug ctd:C045362 prochloraz CTD 1.11E-06 3.61E-02 2.39E-04 2.62E-03 29 268 "LRRC7,ERICH3,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,ASTN1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,DLGAP3,GDAP1L1,CADM1,NRXN1,NRXN2,NMT2,RGMA,MAGI2,DPP6,RET,CACNG7" Drug 3189_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ACTN2,FABP7,MOBP,TRIM46,ANK2,GAS7,BCO1,SLC6A9,SHANK2,ASCL1,SLCO1A2,ASTN1,MYH7,GLS,NHLH1,HAP1,GRIK2,PACSIN1,FAM131B,JAKMIP2,KCNMA1,RALGDS,DTNA,VWA5A" Drug 5905_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "CEND1,KCNIP2,KIAA1109,SEMA6A,FGR,RASA3,SLC1A7,BCO1,TNIK,CADM3,NMNAT2,CPLX2,NCAM1,TMEM151B,INA,KCNK10,SEZ6L,TMPRSS5,SULT4A1,VAV2,MAPK10,KCNJ4,TTLL7,RASGRP2" Drug 5605_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "DPF1,ASIC1,EMID1,ADCY2,FABP7,LRRTM4,FHL1,AMPH,ANK1,FYN,SOX10,NCAM1,WSCD1,NUMA1,BRSK2,CRB1,DAAM2,LILRA4,ADGRG1,CNTN1,FAM13C,SIDT2,VWA5A,RASGRP2" Drug 2873_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "EMID1,ARID1A,PLA2G6,SLC30A10,AMPH,RASA3,DOCK10,PKNOX2,SHANK2,SLN,IGSF9B,ATP2B2,NCDN,ATF7,CACNB2,NRGN,NEURL1,KCNK10,FADS2,PACSIN1,SNCAIP,ELMO1,RAD52,ATN1" Drug 2433_UP Felodipine [72509-76-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "SYNDIG1,ADORA1,KIAA1109,SEMA6A,HPCAL4,BCAS1,FXYD6,FGF17,GPM6A,ATP13A2,ZFYVE9,FLRT1,DZIP3,CTNND1,PLPPR1,PTHLH,CNIH3,KCNH1,RABGAP1L,DSCAM,NUP214,ST8SIA3,TTLL7,SEC61A2" Drug 6383_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "NDRG2,KIAA1109,FGF1,APC,BCAN,SHANK2,SORCS3,FYN,GAD2,INKA2,GNG3,CACNB2,CELF3,PAX6,NMT2,POU3F2,CRMP1,SDC3,FAM131B,PTPRD,KCNMA1,L1CAM,NUP214,EN2" Drug 3361_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "DPF1,ARID1A,NDRG2,AGT,KIAA1109,ASIC4,FHL1,APBA2,SLCO1A2,TAGLN3,ATP2B2,ZCCHC24,GAD2,NEUROD1,GLS,PSD3,PAX6,IFFO1,CRMP1,ATRNL1,RIMS3,KCNMA1,RAB3IL1,DTNA" Drug 4757_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ASIC1,FHL1,MOBP,FOXG1,AMPH,CDC42BPA,ANK2,BCAN,NLGN1,MSR1,TAGLN3,ZCCHC24,GAD2,GPR162,GNG3,TGFBR3,PTGDR2,VCAN,PKN2,PROX1,SYNC,PTCH1,KCNMA1,VWA5A" Drug 3820_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ASIC1,NLGN4X,AGT,FOXG1,AMPH,SORBS1,AQP4,BCO1,SLN,SORCS3,ATP2B2,CPLX2,NPAS3,RND1,ACSBG1,PRUNE2,NPPA,PDE2A,SULT4A1,KCND3,TMEM255A,RGS10,EFNA3,VWA5A" Drug 3810_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "FOXRED2,MOBP,AMPH,APC,SLC2A5,SHANK2,PDE8B,SLN,ATP1A2,ATP2B2,SOX10,CPLX2,ALDH1L1,INKA2,CDK5R2,USP2,TNFRSF1B,PDE3B,HPSE2,TUB,PLCH2,TOX,PTAFR,DNAH9" Drug 2234_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "DPF1,ASIC1,ASIC4,FHL1,MOBP,CDC42BPA,SLC1A7,PKNOX2,ASCL1,CCDC181,EMC1,RND1,NPPA,ADAMTS8,GRM3,TNS1,SEZ6L,SULT4A1,PACSIN1,SNCAIP,PROX1,SRGAP3,KCNMA1,RAD52" Drug 3671_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "EMID1,KIAA1109,MOBP,ANK2,SLC1A7,PDE8B,SLCO1A2,ATP1A2,SCN3B,ALDH1L1,GLS,VAMP1,ADAMTS8,PADI2,TNS1,PTGDR2,SEZ6L,ARHGAP22,CAMKV,IFFO1,RIMS3,PHYHIP,STMN4,KCNJ9" Drug 2867_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "RTN1,SLC30A10,ITSN1,MSR1,PKNOX2,DNAH17,WDTC1,NPAS3,NEUROD1,SLCO1C1,VAMP1,NPPA,ZEB1,NUMA1,DAAM2,CDH8,TPM3,GPR37L1,SERPINE2,CRMP1,MAGI2,DLG2,RAD52,ATN1" Drug 2472_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "MBP,SYNDIG1,RYR1,ADORA1,PLA2G6,PKP4,B3GAT1,ALDH4A1,CPLX2,PHLDB1,BTRC,GPM6B,ATF7,GRM3,ATP13A2,CDC42,RBFOX2,PRMT8,CHI3L2,ZFYVE9,ITIH2,CNIH3,PID1,ATN1" Drug 4358_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "APC2,NDRG2,ADORA1,AGT,PLA2G6,APBA2,GAS7,RPH3A,SLC1A7,MSR1,CSPG5,TAGLN3,ADGRB2,ALDH1L1,WSCD1,TNS1,CDH8,SCRG1,CAMKV,CRMP1,CHD5,KCND3,LPAR6,EPB41" Drug 4458_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.26E-06 4.09E-02 2.52E-04 2.76E-03 22 171 "ABAT,TUBB4A,TESK2,SORBS1,BRINP2,FYN,RGL1,RND1,ACSBG1,GLS,KAZN,PCDH9,CADM1,NMT2,DNAJC12,PROX1,RIMS3,DNAJC6,JAKMIP2,PLPPR4,EFNA3,VWA5A" Drug CID000097812 decahydroisoquinoline Stitch 1.28E-06 4.16E-02 2.52E-04 2.76E-03 7 16 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug ctd:D000726 Androgen Antagonists CTD 1.31E-06 4.24E-02 2.52E-04 2.76E-03 14 75 "NLGN1,SLC1A6,SHANK2,GLS,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2" Drug CID000003559 haloperidol Stitch 1.32E-06 4.28E-02 2.52E-04 2.76E-03 37 394 "ABAT,ADCY2,SLITRK1,AGT,FOXG1,FOXM1,SLC1A2,SOX10,GAD2,NPAS3,ABCC8,CACNA1A,CACNA1E,NPPA,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PAH,PDE4B,PDYN,NTSR2,CHRM1,PACSIN1,PTPA,PKN2,KCNA1,KCNA2,KCNA4,PTPRD,KCNH1,DTNA" Drug CID000040159 trans-permethrin Stitch 1.36E-06 4.41E-02 2.52E-04 2.76E-03 15 86 "ACHE,NDRG2,ADCY2,RYR1,SCN4B,API5,SCN3B,SOX10,GFAP,ASIC3,CP,KCNA1,KCNA2,CAMK1G,PHC2" Drug 4641_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ASIC1,FOXRED2,KIAA1109,FOXG1,CDC42BPA,SLC1A7,PDE8B,SLN,ASTN1,ATP2B2,TNIK,NDUFA5,OPCML,TGFBR3,CDC42,CDH10,SF1,SDC3,ARHGEF4,CTNND2,FAM131B,SMG7,PEX5,RGR" Drug 4359_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "FHL1,SLC30A10,SLC2A5,SLC14A1,FYN,ARPP21,PHLDB1,SLCO1C1,ABCC8,CACNB2,GRIK2,TNS1,CDH8,PCSK2,GPR37L1,SLC22A6,SULT4A1,VCAN,RIMS3,PTPRO,NTM,TTLL7,ELAVL3,RASGRP2" Drug 4648_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ACTN2,KIAA1109,FGF1,ANK1,SLC8A2,ASCL1,SNAP25,B3GALT2,MYH7,ADGRB2,ADAMTS8,P2RX7,CDH10,TPM3,GPR37L1,CABP1,KCNA2,KCNH1,KCNMA1,DSCAM,DTNA,ABCC9,RGR,RASGRP2" Drug 2526_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "CDHR1,ACTN2,LRRTM4,KIAA1109,ANK3,RASA3,SLCO1A2,CADM3,GAD2,NCAM1,GNG4,CAMSAP2,TCF7L2,GRIN1,PHKG1,NRXN2,CNTN1,KLK6,KCNC1,KCND3,KCNK1,SLC17A6,ABCC9,ROM1" Drug 5731_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "PRR5L,KLRC4,ASIC4,SELL,APBB1,APC,SLC1A7,WDTC1,ALDH1L1,GPM6A,OPCML,TNS1,PCSK2,PDE2A,TMPRSS5,CADM1,PTAFR,PLPPR1,KCND3,KCNJ4,RABGAP1L,KCNMA1,FAM13C,LMO1" Drug 2385_UP Cortisone [53-06-5]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ADCYAP1R1,ADORA1,HPCAL4,MOBP,ZNF365,SLC1A7,PKNOX2,PDE8B,TNIK,CADM3,ALDH1L1,VAMP1,ATF7,GRM3,RBFOX2,CHRNB2,SULT4A1,MAPK8,PROX1,BRINP3,ITIH2,KCND3,SLC17A6,LRRC23" Drug 5526_UP Prednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "FHL1,HPCAL4,CDC42BPA,SYBU,ZSWIM8,ROBO3,GNG3,PRUNE2,WSCD1,CACNB2,CAMK2A,TNS1,PCSK2,FLRT1,VCAN,MAPK10,EDRF1,PLPPR1,HP1BP3,KCNMA1,ATG16L1,DTNA,EN2,LRRC23" Drug 5104_UP Flumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "DPF1,ADCY2,ADORA1,MOBP,RASA3,APBB1,APC,SORBS1,BCAS1,SLC2A5,SORCS3,ALDH4A1,CADM3,MLC1,MYRF,GPR19,GRIK2,TNS1,ADGRG1,NRXN2,IFFO1,CTNND2,AK5,RASGRP2" Drug 3759_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "TTYH1,MBP,SYNDIG1,PAQR6,NDRG2,AQP4,SLC2A5,INKA2,VAMP1,GNG4,NUMA1,BRSK2,GRIN1,GRM3,SEZ6L,PDE2A,NRXN1,CAMKV,PACSIN1,KCNA4,KCND3,ARNT2,RASGRF1,OLIG2" Drug 2506_UP Estropipate [7280-37-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "MAG,KCNIP2,ADCY2,ADORA1,HPCAL4,ANK3,AQP4,SLC6A9,SLN,ATP1A3,SOX10,NEUROD1,ASTN2,TCF7L2,GRIA4,GRIN1,ADAMTS8,USP2,PHKG1,NRXN2,CABP1,RIMS3,KCND3,ST8SIA3" Drug CID000037165 saxitoxin Stitch 1.37E-06 4.46E-02 2.52E-04 2.76E-03 13 65 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ANK2,SCN3B,MYH7,NKX6-2,NEUROD1,TF,ASIC3,SLC25A18" Drug 5217_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-06 4.52E-02 2.54E-04 2.79E-03 22 172 "ADD3,TUBB4A,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,VWA5A" Drug 3528_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.50E-06 4.87E-02 2.70E-04 2.96E-03 24 200 "NDRG2,AQP4,SLCO1A2,DNAH17,ALDH1L1,RND1,GNG4,BTRC,WSCD1,NPPA,CACNB2,PSD3,GRIA1,GRIN1,OLR1,CDH10,ADGRG1,PLEKHB1,VAV2,NECAB2,OSBPL3,PSD,ATN1,RASGRP2" Drug 3833_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.50E-06 4.87E-02 2.70E-04 2.96E-03 24 200 "CEND1,NDRG2,ADCY2,SELL,SLC2A5,ASPH,BRINP2,ATP2B2,NEUROD1,ATF7,USP2,PTGDR2,PDE3B,CHRNB2,FADS2,SNCAIP,PTHLH,ITIH2,TMCC2,NKAIN1,PID1,VWA5A,ELAVL3,EN2" Drug ctd:D010406 Penicillins CTD 1.51E-06 4.91E-02 2.70E-04 2.96E-03 6 11 "SLC1A2,MT3,CAMK2A,GRIA1,GRIA2,PLPPR1" Drug CID005039877 sym 2206 Stitch 1.51E-06 4.91E-02 2.70E-04 2.96E-03 6 11 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug ctd:D003633 Dichlorodiphenyl Dichloroethylene CTD 1.60E-06 5.19E-02 2.84E-04 3.11E-03 31 303 "LRRC7,FOLH1,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,BCL2L2,GFRA1,GJB1,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,TF,CD81,TNFRSF1B,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,PTCH1,MAGI2,DPP6,RET,CACNG7" Drug ctd:D008694 Methamphetamine CTD 1.67E-06 5.44E-02 2.96E-04 3.24E-03 92 1407 "PRR5L,MAPT,MBP,SYT9,LGR4,ARID1A,SLC25A25,F3,CLIP1,PLEKHG5,FABP7,ADORA1,ADORA3,SH3GL2,DGKZ,TACC2,SORBS1,SLC1A2,SLC2A5,SLC6A9,MT3,LGI3,TAGLN3,SORCS3,SNCB,FYN,PALLD,GAD2,MYH7,NKX6-2,TTLL9,ADAM15,CPLX2,BCL2L2,NDUFA5,GFAP,PHLDB1,SEPT3,AJAP1,GLS,ZNF638,ASTN2,CNTN2,GOLGB1,PRUNE2,ACSL6,NEU4,GPR17,GPR19,PSD3,GRIA1,GRIA2,GRIN1,GRM3,PTPN5,TIE1,TNS1,MAGI1,PDE2A,PDE4B,PDYN,ZMYND8,SCRG1,ASIC3,HPCA,PHKG1,MICAL1,PACSIN1,PPP3CB,PUM1,HES5,DPYSL5,ANKS1B,GON4L,PMEPA1,PRDM2,ZC3H11A,AK5,KCNJ4,KCNJ9,ARNT2,SNX27,CAB39L,HS3ST4,RAD52,FAM57B,USH1C,SLC39A12,SIDT2,PLEKHO1,EPB41L1,RASGRP2" Drug ctd:C012568 terbufos CTD 1.71E-06 5.54E-02 3.00E-04 3.28E-03 56 724 "EPS8,RIMKLA,CDHR1,MBP,ADCY2,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug CID000001140 toluene Stitch 1.87E-06 6.06E-02 3.26E-04 3.57E-03 22 175 "ASIC1,SCN3A,SCN4B,SCNN1D,LRRC7,ASIC4,LRRC4C,SCN3B,AHCYL1,DNER,NDUFA5,GFAP,NODAL,LEFTY2,PAX6,ASIC3,ANLN,PRKCG,PKN2,PRKCZ,CDH20,ROM1" Drug CID000127988 "4,6-dichloroindole-2-carboxylic acid" Stitch 1.93E-06 6.27E-02 3.35E-04 3.67E-03 5 7 "B3GAT1,GRIA1,GRIA2,GRIA4,GRM3" Drug ctd:D009538 Nicotine CTD 1.98E-06 6.44E-02 3.43E-04 3.76E-03 71 1005 "ACHE,MBP,SYT9,LDLRAD3,ARID1A,F3,ADCYAP1R1,GRAMD1B,TUBB4A,HPCAL4,SFPQ,RASA3,NTNG1,BCAS1,API5,CLSTN1,AQP4,RPH3A,MADD,MT3,CCDC88A,CGREF1,ADGRA1,ATM,FYN,KIF21B,ARPP21,NPAS3,NCAM1,NDUFA5,GFAP,PHLDB1,ARHGEF7,SYT4,DDHD2,ACSL6,ZEB1,PTBP2,EML4,CAMK2A,GRIK2,GPR88,TJP1,CDC42,ZMYND8,ADGRG1,CHGA,CHRNB2,HPCA,OPALIN,CCDC136,CNTN1,FEZ1,VCAN,CMTM5,PKN2,PRKCZ,IGSF1,MAPK8,PROX1,PTAFR,ITGAV,HP1BP3,MED24,KCND3,AK5,KCNK1,SLC25A48,SLC17A6,ST8SIA3,RLBP1" Drug 2375_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.12E-06 6.89E-02 3.64E-04 4.00E-03 23 190 "NDRG2,F3,ADD3,ADORA1,ATP2B2,ZCCHC24,CADM3,NCAM1,RGL1,CAMSAP2,MYRF,NRGN,GRIN1,JAM2,BEST1,CRMP1,DZIP3,CTNND1,RIMS3,DNAJC6,EFNA3,VWA5A,EPB41L1" Drug CID000003837 AC1L1GTT Stitch 2.22E-06 7.22E-02 3.80E-04 4.17E-03 26 233 "MBP,KCNIP2,RYR1,AGT,SNAP25,MYBPC1,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRM3,P2RX7,HMGB1,SLC22A6,CAMKV,CHD1L,PTPA,PRKACB,PRKCG,KCNC1,KCND3,KCNJ4,CAMK1G,NUP214" Drug 3395_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug 7324_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SYBU,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,VAMP1,PADI2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,NAV2,EFNA3" Drug 6493_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SORBS1,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,ZEB1,PADI2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,VWA5A" Drug CID000003598 hexachlorophene Stitch 2.46E-06 8.00E-02 4.12E-04 4.52E-03 15 90 "PLA2G6,MOBP,CCDC88A,SCG3,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CDH8,ANKS1B" Drug 3332_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.54E-06 8.25E-02 4.23E-04 4.64E-03 23 192 "TUBB4A,FHL1,C1orf61,AMPH,RASA3,PKNOX2,FYN,WDTC1,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ABCC8,OMG,CCKBR,USP2,CHI3L2,PIK3CD,DNAJC12,KCND3,TMCC2,ST8SIA3" Drug CID004223812 sunifiram Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID009964065 3-isoxazolol Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011105661 4-(chloromethyl)-3-methoxy-5-methylisoxazole Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID006857345 AC1OAGFB Stitch 2.64E-06 8.57E-02 4.31E-04 4.72E-03 45 540 "ASIC1,ADCY2,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,AMPH,RASA3,SH3GL2,DGKZ,DGKD,RPH3A,ARFGAP1,SCN3B,ABCC8,GNAS,GNG3,KCNK10,REPS2,CDC42,ASIC3,CHRM1,TUB,PIK3CD,SDC3,PRKCG,PKN2,PRKCZ,SYTL2,PLPPR5,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ9,KCNJ10,KCNQ2,DNM2,RASGRF1,BSCL2,EPB41,EPB41L1,EPB41L2,RASGRP2" Drug 2794_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.73E-06 8.86E-02 4.43E-04 4.86E-03 22 179 "ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,ZNF365,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,POPDC3,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,VWA5A" Drug CID000002252 Atpa Stitch 2.92E-06 9.48E-02 4.72E-04 5.17E-03 6 12 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug CID000004914 procaine Stitch 2.96E-06 9.61E-02 4.76E-04 5.22E-03 20 153 "ASIC1,ACHE,RYR1,TUBB4A,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNA1A,CACNA1E,CACNB2,ASIC3,CHRM1,CHRNB2,PRKCG,PKN2,PRKCZ,TUBB2B,CACNG7" Drug 4260_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.04E-06 9.86E-02 4.86E-04 5.33E-03 23 194 "ABAT,ACHE,RYR1,MOBP,RASA3,SORBS1,SLC1A6,ASCL1,INKA2,NEUROD1,NUMA1,TF,USP2,PDE3B,ADGRG1,CHI3L2,DUSP26,CABP1,RGS6,PRDM2,KCNC1,RASGRF1,PAK5" Drug 2881_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.28E-06 1.07E-01 5.18E-04 5.68E-03 22 181 "TUBB4A,SEMA6A,SORBS1,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,WSCD1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,JAKMIP2,MAGI2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug 2504_UP Skimmianine [83-95-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "MAG,ACHE,KCNIP2,ADCY2,MOBP,SORBS1,SHANK2,PDE8B,SLCO1A2,TAGLN3,SLN,ATP1A3,GAD2,ARPP21,CDK5R2,BTRC,GRIA4,KCNK10,PRMT8,RGS6,ZBTB16,KCNJ4,ST8SIA3" Drug 4971_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "NDRG2,FGF1,WDTC1,ALDH1L1,RND1,POPDC3,KAZN,BTRC,WSCD1,GPM6B,CACNB2,TCF7L2,NUCB1,CCKBR,ZMYND8,CNTN1,NECAB2,VCAN,EDRF1,RIMS3,SSPN,SIDT2,VWA5A" Drug 6159_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "NDRG2,PLA2G6,FHL1,MOBP,CDC42BPA,SHANK2,GPR153,ACSBG1,GLS,ROBO3,WWC1,WSCD1,HAP1,CRB1,CHGA,CHRNB2,BEST1,MAPK10,KCNMA1,CRTAC1,SIDT2,EFNA3,RASGRP2" Drug 2566_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "CEND1,NDRG2,FHL1,PPM1E,B3GAT1,PALLD,TNIK,RAP1GAP2,NCAM1,RGL1,PHLDB1,VAMP1,GPR19,INA,PADI2,FLRT1,FEZ1,DZIP3,EDRF1,RIMS3,DNAJC6,TTLL7,ABI2" Drug CID000009238 adamantane Stitch 3.42E-06 1.11E-01 5.32E-04 5.83E-03 10 41 "FOLH1,NEU4,GRIA1,GRIA2,GRIA4,GRM3,P2RX7,TNS1,MED1,CTNND1" Drug CID000002548 AC1L1DXE Stitch 3.49E-06 1.13E-01 5.32E-04 5.83E-03 30 299 "ACHE,RYR1,ADORA1,SCNN1D,ACTL6B,ANK1,ANK2,ANK3,FOLH1,B3GAT1,GFAP,CACNA1A,CACNA1E,CACNB2,GRIK3,GRIK4,CCKBR,HRH3,PDYN,CHGA,ASIC3,CHRM1,PIK3CD,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PYGM,CACNG7" Drug CID000000942 Nicorette Stitch 3.57E-06 1.16E-01 5.32E-04 5.83E-03 44 529 "ASIC1,ACHE,F3,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,CCDC80,SLC8A2,GABBR1,SCN3B,GFAP,GFRA1,NODAL,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,LEFTY2,ZFP91,PDYN,HAPLN2,HMGB1,CHGA,ASIC3,CHRM1,CHRNB2,PIK3CD,ACBD5,PRKACB,PRKCG,PKN2,PRKCZ,PSMD13,KCNC1" Drug CID005311098 Ns102 Stitch 3.58E-06 1.16E-01 5.32E-04 5.83E-03 8 25 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,MAPK8,MAPK10" Drug 4453_UP clozapine; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,ACTN2,SCNN1D,MOBP,PPM1E,DDX25,ATP2B2,KIF21B,CADM3,GAD2,NCAM1,NEUROD1,GNG4,ADGRL3,GRIA4,HPCA,CAMKV,EDRF1,TOX,RABGAP1L,ARNT2,ATN1,DSCAM" Drug 5740_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,EMID1,KIAA1109,FOXG1,DOCK10,GAS7,AQP4,PKNOX2,TAGLN3,ADGRB2,GPM6A,ATF7,NPPA,EML4,GRIN1,OPCML,PLEKHB1,SPATA6,SRGAP3,AK5,ST8SIA3,EN2,RASGRP2" Drug 3375_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,TUBB4A,FHL1,C1orf61,AMPH,GAS7,RPH3A,SHANK2,DLL3,ASPH,SLN,NDUFA5,AJAP1,ZEB1,TNS1,CDH8,CHI3L2,SULT4A1,SNCAIP,TOX,RABGAP1L,KCNMA1,ELAVL4" Drug 3369_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "CEND1,ACTN2,NDRG2,ADCY2,GAS7,SLC6A9,SHANK2,SLCO1A2,IGSF9B,ATP1A3,WSCD1,DAAM2,TNS1,CDH8,LILRA4,PDE1C,ZFYVE9,PIK3CD,SULT4A1,PTAFR,ITIH2,MAGI2,TMCC2" Drug 2501_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "TUBB4A,ANK3,PPM1E,APC,SLCO1A2,SLN,SNAP25,GAD2,SPART,BCL2L2,FAM168A,BTRC,NPPA,ZEB1,NUCB1,ATP13A2,OMG,CDH10,TPM3,SULT4A1,CNTN1,MAGI2,DTNA" Drug 6169_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "CHST15,PLA2G6,ASIC4,CDC42BPA,SHANK2,GPR153,SLCO1A2,ASTN1,CPLX2,SLCO1C1,ASTN2,BTRC,GPM6B,GPR19,OPCML,TPM3,ZMYND8,ASIC3,MICAL2,AK5,ATN1,DSCAM,NUP214" Drug 3604_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "MBP,SYNDIG1,NDRG2,FABP7,GRAMD1B,SELL,AMPH,SORBS1,SHANK2,ATP2B2,GAD2,RND1,POPDC3,GNG3,INA,PACSIN1,POU3F4,MICAL2,MASP1,PTAFR,KCND3,DPP6,RASGRP2" Drug 3726_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "ACTN2,NDRG2,ADORA1,FGF1,TRIM46,APBB1,ASPH,ALDH4A1,SCN3B,TNIK,KIF21B,SLCO1C1,GPR19,USP2,TNS1,PDE2A,PDE4B,CHI3L2,CHRNB2,SULT4A1,EDRF1,PRDM2,DSCAM" Drug 3696_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "ACTN2,FGR,C1orf61,APBB1,RPH3A,CGREF1,SLCO1A2,BRINP2,MYH7,GNAS,KLHL4,GPM6A,ZEB1,GRM3,TPM3,MAGI1,CHI3L2,RIMS3,PTPRO,NKAIN1,ABCC9,RGS7,RAVER2" Drug 1000_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.83E-06 1.25E-01 5.41E-04 5.94E-03 21 169 "ADD3,TUBB4A,GPR153,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,PCDH9,PIK3CD,DNAJC12,MAPK8,KIAA0513,RIMS3,PTCH1,DNAJC6,JAKMIP2,EFNA3" Drug 4226_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ARID1A,ADORA3,MOBP,ANK3,PKP4,NTNG1,MSR1,TNIK,NFASC,WWC1,CACNB2,GPR17,OLR1,NEURL1,REPS2,MAGI1,PDE3B,CA14,SULT4A1,NECAB2,IFFO1,FEZ1,SRGAP3" Drug 6614_UP Apramycin [37321-09-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "KCNIP2,ADORA1,ANK1,AQP4,BRINP2,CCDC181,ATP2B2,SOX10,SLCO1C1,PRUNE2,GRIA1,NEURL1,CA14,SPATA6,IFFO1,CHD5,CTNND2,ECE2,PROX1,PTCH1,RAB3IL1,DNAH9,VWA5A" Drug 6514_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ACTN2,TUBB4A,FHL1,ANK1,GAS7,SLC1A7,MSR1,ADAM15,PHLDB1,AJAP1,GLS,GNAS,GRIK2,USP2,ZFYVE9,KIAA1549L,CAMKV,RGS6,VCAN,PROX1,HP1BP3,DTNA,RCAN2" Drug 6423_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ARID1A,NLGN4X,SCN3A,SH3GL2,ZCCHC24,EMC1,NPAS3,NEUROD1,GPM6A,ATF7,CACNB2,GRM3,GUCY1A2,PCDH9,SEZ6L,ZMYND8,SCRG1,PRRX1,CHD1L,MAPK8,EDRF1,PTCH1,DTNA" Drug 4642_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "FOXRED2,APC,SLC1A7,SLC6A9,ASTN1,FYN,ATP2B2,CADM3,EMC1,ADGRB2,NEUROD1,GLS,BTRC,ADGRL3,GRIK2,GPR37L1,CHI3L2,CADM1,CABP1,DTNA,ST8SIA3,RGR,RGS10" Drug 5616_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "DPF1,MAG,EXTL1,RYR1,MOBP,C1orf61,RPH3A,ASCL1,NMNAT2,NPAS3,GFAP,MLC1,POPDC3,PRUNE2,GRIA1,ADAMTS8,PCDH9,HPSE2,MICAL1,NECAB2,MAPK8,NOS1AP,PTAFR" Drug 4229_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "TTYH1,ABAT,SLC8A2,ASCL1,MYH7,NCAM1,NEUROD1,VAMP1,ADGRL3,PRUNE2,ADAMTS8,PHKG1,CADM1,NRXN2,BEST1,NOS1AP,PRDM2,KCNC1,SRGAP3,CAMK1G,ST8SIA3,RGR,LRRC23" Drug 4631_DN Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "MAPT,FOXG1,SLC1A7,SLC14A1,PDE8B,ATP2B2,CADM3,ADGRB2,NEUROD1,BTRC,ADGRL3,CACNA1A,OPCML,TNS1,CDH10,NMT2,CTNND2,SMG7,PEX5,RAB3IL1,ATG16L1,ATN1,RGR" Drug 2511_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "AGT,BCAR3,SLCO1A2,TAGLN3,B3GAT1,ALDH4A1,ATP1A2,ATP1A3,MYBPC1,GAD2,ACSBG1,TCF7L2,CAMK2A,BRSK2,ADAMTS8,GUCY1A2,TLL2,CTNND1,RIMS3,KCNC1,AK5,DLG3,TTLL7" Drug 5953_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ACTN2,WLS,NDRG2,ADORA1,PLA2G6,SLC1A7,BRINP2,EMC1,PHLDB1,GNG4,BTRC,GPR19,GRIN1,TF,NECAB2,PTHLH,KCND3,KCNJ4,PEX5,DTNA,EFNA3,EN2,LRRC23" Drug 6715_UP Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "MOBP,PKP4,NTNG1,PKNOX2,MYH7,INKA2,SLCO1C1,GPM6B,GRIK2,TNS1,PTGDR2,NMT2,PMP2,IFFO1,ATRNL1,MAPK8,PROX1,PTCH1,AK5,ST8SIA3,SIDT2,OLIG2,RASGRP2" Drug 2864_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "DPF1,EMID1,ADORA1,PLA2G6,SLC1A7,BCO1,PKNOX2,TAGLN3,WDTC1,NEUROD1,GLS,NPPA,CACNB2,CAMK2G,ADAMTS8,OPCML,ZFYVE9,PIK3CD,PACSIN1,RIMS3,PTCH1,ITIH2,TMCC2" Drug 3513_UP Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "C1orf61,APBA2,SYBU,BCO1,BRINP2,COLGALT2,RND1,GNAS,BTRC,HAP1,NUCB1,PSD3,PDE1C,PDE3B,ADGRG1,FADS2,SDC3,MAPK10,EDRF1,NOS1AP,ATN1,DSCAM,DTNA" Drug 3694_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "PAQR6,GRAMD1B,MOBP,ANK1,DOCK10,APC,SHANK2,ASPH,ATP1A3,MLC1,BTRC,GPM6B,CRB1,SPX,PDE2A,SULT4A1,SYTL2,PHYHIP,PRDM2,PTPRO,NTM,ARNT2,RALGDS" Drug ctd:C109476 epoxiconazole CTD 3.95E-06 1.28E-01 5.41E-04 5.94E-03 33 348 "FGF1,PLA2G6,LRRC7,ANXA7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,FAM168A,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,PC,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,ETNPPL,CHD1L,FEZ2,SIRPA,ITIH2,MAGI2,DPP6,CACNG7" Drug CID000005917 pentylenetetrazol Stitch 4.02E-06 1.31E-01 5.49E-04 6.02E-03 18 130 "ABAT,ACLY,ADGRV1,ADORA1,ADORA3,GAD2,GFAP,ZEB1,GRIA1,GRIA2,GRIA4,GRM3,HRH3,PDYN,SLC36A4,TOX,PTCH1,KCNA1" Drug CID000105153 rubidium Stitch 4.18E-06 1.36E-01 5.54E-04 6.07E-03 12 61 "AGT,SLC14A1,ATP1A2,ATP1A3,DDR1,P2RX7,KCNA4,KCNC1,KCNJ4,KCNJ9,KCNJ10,KCNMA1" Drug 6736_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.21E-06 1.37E-01 5.54E-04 6.07E-03 21 170 "DPF1,ABAT,MAPT,CEND1,TUBB4A,SORBS1,BRINP2,FYN,TNIK,RGL1,GLS,USP2,REPS2,PCDH9,DNAJC12,KIAA0513,SYTL2,DNAJC6,PLPPR4,SRGAP3,EFNA3" Drug 1522_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "DPF1,EMID1,RYR1,ADORA1,MOBP,ITSN1,DOCK10,SLC1A7,GPR153,ATP1A3,ZCCHC24,SPART,POPDC3,CACNA1A,PRUNE2,ZEB1,NUMA1,PIK3CD,VAV2,ITIH2,MAGI2,KCNK2,RAD52" Drug 1466_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "C1orf61,BCAN,BCAS1,GPR153,DLL3,ASPH,GNG3,HAP1,USP2,CDC42,CDH10,ZMYND8,MICAL1,PACSIN1,CRMP1,SDC3,RIMS3,PHYHIP,PLPPR1,PTHLH,PRDM2,KCNMA1,ATN1" Drug 6843_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "EMID1,RYR1,KIAA1109,SEMA6A,FHL1,C1orf61,SELL,RASA3,CCDC88A,SLCO1A2,FYN,ZCCHC24,AJAP1,MLC1,VAMP1,WSCD1,HAP1,GRIN1,ADGRG1,POU3F4,CHD5,RABGAP1L,KCNMA1" Drug 4346_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "SLC30A10,MOBP,GAS7,SORBS1,CPLX2,SPART,SLCO1C1,POPDC3,ATF7,GRM3,OPCML,CELF3,KCNK10,TNS1,CDH8,MASP1,KCND3,SRGAP3,ATN1,RASGRF1,FAM13C,LMO1,ELAVL3" Drug 3092_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "SYNDIG1,ADORA1,BCAR3,FHL1,AMPH,PKNOX2,PDE8B,SLN,TNIK,GNG4,OMG,TJP1,NEURL1,TNS1,PCDH9,PDE1C,ZFYVE9,VAV2,CNTN1,POU3F2,POU3F4,SYTL2,ATN1" Drug 3612_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "KIAA1109,APC,GPR153,SNAP25,ATP2B2,SOX10,GAD2,NEUROD1,RND1,ACSBG1,BTRC,INA,CDC42,PTGDR2,ZFYVE9,NECAB2,POU3F2,VCAN,PTAFR,CA10,SRGAP3,TTLL7,OLIG2" Drug 2279_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "MBP,TUBB4A,KIAA1109,APC,SLC1A2,SLC2A5,DLL3,FYN,PHLDB1,ROBO3,PSD3,NEURL1,TNS1,VAV2,CABP1,POU3F4,CRMP1,PLCH2,ITIH2,KCND3,ATN1,ST8SIA3,RASGRP2" Drug 5916_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "CEND1,MOBP,CDC42BPA,APC,GAS7,ZNF365,SLC2A5,ASCL1,BRINP2,FYN,ZCCHC24,GLS,TGFBR3,TNS1,PDE1C,PDE3B,CA14,RIMS3,PARD6A,KCNMA1,DTNA,SSPN,ELAVL3" Drug 2269_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ACTN2,ARID1A,MOBP,C1orf61,SLC1A2,PDE8B,ATP2B2,CADM3,SOX10,SPART,ALDH1L1,FGF17,RND1,ABCC8,GLS,ADGRL3,WSCD1,TGFBR3,PRMT8,VCAN,SDC3,PTHLH,CRTAC1" Drug 3196_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "MAPT,ADORA1,FOXG1,MSR1,SHANK2,SLCO1A2,ASTN1,ATP1A2,RND1,SLCO1C1,ADGRL3,GPM6A,GPM6B,HAP1,GRIN1,GRM3,NMT2,IFFO1,MICAL2,VCAN,RIMS3,USH1C,VWA5A" Drug 4101_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ABAT,ADCY2,FOXRED2,AGT,ST8SIA1,AQP4,MSR1,BRINP2,MYT1L,PRUNE2,DDR2,PDE2A,CHI3L2,CABP1,SPATA6,POU3F2,RGS6,MICAL2,NOS1AP,PRDM2,DSCAM,RGR,EPB41" Drug 4650_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ABAT,ACTN2,FABP7,SELL,DNAH17,B3GALT2,MYH7,GRIK3,OLR1,USP2,P2RX7,CDH10,ST8SIA5,SULT4A1,CABP1,SPATA6,POU3F2,RGS6,KCND3,KCNH1,RABGAP1L,ATN1,CAMK1G" Drug CID000093460 pyraclofos Stitch 4.40E-06 1.43E-01 5.63E-04 6.17E-03 16 106 "SCN4B,ANK2,SCN3B,CACNA1A,CACNB2,ASIC3,CHRM1,PRKCG,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,CACNG7" Drug ctd:D011188 Potassium CTD 4.40E-06 1.43E-01 5.63E-04 6.17E-03 16 106 "ADORA1,AGT,SHANK2,ABCC8,KCNK10,PDYN,MAPK8,KCNC1,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,ABCC9" Drug CID005459389 DB04780 Stitch 4.62E-06 1.50E-01 5.78E-04 6.34E-03 21 171 "MAG,MBP,F3,MOBP,MOG,SELL,BCAN,ST8SIA1,B3GAT1,GFAP,ADAMTS8,OMG,TNR,HMGB1,PMP2,VCAN,PRKCG,PKN2,PRKCZ,ARHGEF4,KLK6" Drug 1373_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "MBP,SEMA6A,C1orf61,PPFIA1,CADM3,ADGRB2,GJB1,PHLDB1,GLS,GNG4,CACNA1A,NPPA,OMG,KCNK10,ZMYND8,CHRNB2,DUSP26,SERPINE2,CAMKV,PACSIN1,CRMP1,TMCC2,DLG3" Drug 4008_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "MAPT,KCNIP2,PLA2G6,FGF14,HPCAL4,SNCB,CADM3,ZSWIM8,ADGRB2,PHLDB1,BTRC,GPM6B,ZEB1,NEURL1,CDC42,MAGI1,RGS6,PTCH1,KCNC1,BEND5,DTNA,ABCC9,USH1C" Drug 3557_UP Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "EMID1,NDRG2,RTN1,FHL1,AMPH,APBA2,GPR153,SLN,ALDH4A1,ATP1A3,DKK3,RND1,WSCD1,NPPA,PC,TNS1,GPR37L1,PMP2,ATRNL1,PLPPR1,RLBP1,SSPN,EFNA3" Drug 4532_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "ACHE,MDM4,FGF1,HPCAL4,RASA3,BCAN,SCN3B,TNIK,ACSBG1,VAMP1,PRUNE2,HAP1,PDE2A,CHI3L2,CHRNB2,CCSER2,NECAB2,CTNND2,KCNC1,RABGAP1L,RASGRF1,ST8SIA3,EPB41" Drug 4259_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "ARID1A,AGT,AQP4,SLC1A6,ASCL1,SLCO1A2,SNAP25,CCDC181,ATP1A2,NFASC,INKA2,GRIK3,P2RX7,PTGDR2,NRXN1,CABP1,NOS1AP,KCNH1,SUSD4,ABCC9,CAMK1G,RGR,RASGRP2" Drug 6458_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "SEMA6A,FHL1,BCAN,SLC1A7,ATM,WDTC1,EMC1,BCL2L2,BTRC,CACNA1A,NUDT21,PC,RBFOX2,PIK3CD,MICAL1,SYNC,HP1BP3,TMCC2,DTNA,EFNA3,RBM12,VWA5A,EPB41L2" Drug 6652_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "KLRC4,ADORA3,ANK2,GAS7,MSR1,SLC6A9,DDX25,CADM3,INKA2,KLHL4,SEZ6L,PDE3B,PDE4B,HPSE2,TUB,VAV2,SPATA6,KCND3,SLC17A6,FAM13C,DTNA,CRTAC1,RASGRP2" Drug 5997_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "SYNDIG1,MDM4,FHL1,SELL,CDC42BPA,GAS7,BCO1,PKNOX2,DDX25,SNAP25,GAD2,GFAP,RGL1,NEUROD1,VAMP1,BRSK2,TNS1,MICAL1,CRMP1,RGR,TTLL7,EFNA3,RASGRP2" Drug CID003016733 1-hydroxypyrazole Stitch 4.98E-06 1.62E-01 6.06E-04 6.64E-03 5 8 "SLC1A2,GRIA1,GRIA2,GRIA4,GRM3" Drug CID003614351 1-hydroxyimidazole Stitch 4.98E-06 1.62E-01 6.06E-04 6.64E-03 5 8 "SLC1A2,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000004853 Pirmenolum Stitch 4.99E-06 1.62E-01 6.06E-04 6.64E-03 8 26 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1" Drug CID000219078 lacosamide Stitch 5.00E-06 1.62E-01 6.06E-04 6.64E-03 11 52 "ABAT,ADGRV1,SCN4B,SEMA6A,SCN3B,GRIA1,GRIA2,GRIA4,ASIC3,SV2A,KCNQ2" Drug 5580_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.07E-06 1.65E-01 6.06E-04 6.64E-03 21 172 "ADD3,TUBB4A,SORBS1,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,USP2,PCDH9,PIK3CD,DNAJC12,DNAJC6,JAKMIP2,SRGAP3,EFNA3" Drug CID000656723 LY382884 Stitch 5.08E-06 1.65E-01 6.06E-04 6.64E-03 7 19 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000071249 diprafenone Stitch 5.08E-06 1.65E-01 6.06E-04 6.64E-03 7 19 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug 3623_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "MAPT,ACTN2,KIAA1109,ASIC4,FHL1,SLCO1A2,TNIK,SOX10,CPLX2,GRIA4,GRIK2,OMG,KCNK10,ZFYVE9,POU3F2,CHD5,PHYHIP,ELMO1,SMG7,SRGAP3,KCNMA1,RAD52,OLIG2" Drug 3752_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "CDHR1,APC2,FABP7,KIAA1109,PKP4,NEUROD1,RND1,SLCO1C1,ADGRL3,NUMA1,BRSK2,PCDH9,PDE3B,SULT4A1,IFFO1,FEZ1,MAPK10,MASP1,PTAFR,ATN1,RASGRF1,RGS10,EFNA3" Drug 604_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "GRAMD1B,KIAA1109,PLA2G6,ITSN1,APC,USP33,CADM3,ZSWIM8,NMNAT2,GNG4,TMEM151B,RBFOX2,SEZ6L,PIK3CD,VAV2,CRMP1,SDC3,IGSF1,PLPPR1,JAKMIP2,ITIH2,KCND3,SIDT2" Drug 2202_UP Gossypol [303-45-7]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.14E-06 1.67E-01 6.09E-04 6.68E-03 22 186 "CLIP1,RYR1,ASIC4,HPCAL4,CDC42BPA,PPM1E,RPH3A,PKNOX2,SLN,FYN,SOX10,NPAS3,NPPA,P2RX7,FLRT1,CNTN1,BEST1,NECAB2,PSD,RIMS3,KCND3,DSCAM" Drug CID000129695 Naspm Stitch 5.24E-06 1.70E-01 6.19E-04 6.79E-03 6 13 "B3GAT1,NASP,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000119582 Joro spider toxin Stitch 5.45E-06 1.77E-01 6.39E-04 7.01E-03 10 43 "NASP,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,NUP214" Drug CID000126756 LY 300164 Stitch 5.45E-06 1.77E-01 6.39E-04 7.01E-03 10 43 "FOLH1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,ZFP91,SV2A,KCNQ2" Drug 4112_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.56E-06 1.81E-01 6.50E-04 7.13E-03 21 173 "ADD3,TUBB4A,SORBS1,PKNOX2,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,DNAJC12,DNAJC6,EFNA3,VWA5A" Drug CID000440805 2-amino-5-oxohexanoate Stitch 5.58E-06 1.81E-01 6.50E-04 7.13E-03 18 133 "ADGRV1,FGF1,GFAP,NEUROD1,CNTN2,ZFP91,PAX6,TUB,VCAN,NCAN,RGMA,SV2A,PCDH15,KCNN3,RLBP1,ELAVL3,OLIG2,RPE65" Drug CID000001650 AC1L1BXF Stitch 6.12E-06 1.99E-01 7.10E-04 7.78E-03 14 85 "DGKZ,DGKD,SLC1A2,SLC1A6,SLC1A7,GFAP,MLC1,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,HMGB1,PLPPR5" Drug ctd:C044887 beta-methylcholine CTD 6.39E-06 2.08E-01 7.39E-04 8.10E-03 102 1657 "RABEPK,ASIC1,MAPT,CEND1,ADAR,RTN1,GALNT13,ADD3,CDC7,SORCS1,FOXRED2,SEMA6A,HPCAL4,TRIM46,ITSN1,PKP4,GPAM,ZCCHC17,TACC2,PAAF1,CLSTN1,MIER1,URGCP,NBPF1,ARFGAP2,ASCL1,ARFGAP1,SNAP25,ATM,FYN,PHYHIPL,USP33,SON,NMNAT2,GART,RAP1GAP2,NCAM1,LMO3,ZNF302,GPR162,NELL1,PHLDB1,ARHGEF7,VAMP1,CASTOR3,SYT4,POPDC3,CAMTA1,PSRC1,TCF12,NRDC,CAMK2G,DDR2,NUMA1,GRIN1,FBXL16,GUCY1A1,CELF3,DCLK1,TPM3,TPM4,FNDC5,CHGA,PFKFB3,TUB,HNRNPK,NOMO2,ANLN,UBTF,DNAJC12,CCDC136,IFFO1,SF1,RNF14,CRLS1,PPP3CB,FEZ1,RIMS4,PLD5,PRKCZ,NRSN1,PROX1,RIMS3,GON4L,SPIRE1,PLPPR5,PMEPA1,HP1BP3,PARD6A,SV2A,ARNT2,KCNMA1,PEX5,KCNQ2,KIF2A,ATG16L1,GNE,JMJD1C,ZNF248,RBM12,RPRD1A,TMEM100" Drug CID000004450 nefopam Stitch 6.84E-06 2.22E-01 7.86E-04 8.61E-03 8 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,HRH3,ASIC3" Drug CID000031958 AC1L1MOZ Stitch 6.84E-06 2.22E-01 7.86E-04 8.61E-03 8 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,NKX6-2,ASIC3" Drug 6825_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.27E-06 2.36E-01 8.31E-04 9.12E-03 22 190 "ACTN2,NDRG2,FGF1,ASIC4,SLC6A9,PDE8B,FYN,ZCCHC24,SPART,ALDH1L1,RND1,ACSBG1,GNG3,WSCD1,CCKBR,SULT4A1,PLCH2,MAPK10,RAD52,PARP11,ATN1,TTLL7" Drug CID000003100 diphenhydramine Stitch 7.33E-06 2.38E-01 8.35E-04 9.16E-03 13 75 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ATM,SCN3B,AZIN2,HRH3,NTSR2,ASIC3,CHRM1,KCNJ4" Drug 4665_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ABAT,TUBB4A,TESK2,TAGLN3,BRINP2,FYN,TNIK,RGL1,RND1,VAMP1,USP2,PCDH9,DNAJC12,KIAA0513,RIMS3,SYTL2,DNAJC6,PLPPR4,SRGAP3,EFNA3" Drug 4710_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ADD3,TUBB4A,SORBS1,SYBU,CCDC88A,FYN,TNIK,ZCCHC24,RGL1,RND1,ACSBG1,GLS,SERPINE2,PIK3CD,DNAJC12,DNAJC6,TTLL7,EFNA3,VWA5A,RASGRP2" Drug 3312_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "TUBB4A,HPCAL4,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug 5209_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ADD3,TUBB4A,SEMA6A,SORBS1,ASPH,FYN,TNIK,ZCCHC24,RGL1,ACSBG1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug ctd:D012834 Silver CTD 8.38E-06 2.72E-01 9.39E-04 1.03E-02 116 1958 "MAG,RABEPK,TTYH1,EPS8,ABAT,RIMKLA,MAPT,RCSD1,PAQR6,EXTL1,EYA1,MRVI1,ADAR,DSCAML1,WAC,ADORA3,NLGN4X,FCGR1A,AGT,SCN3A,SEMA6A,BCAR3,TRIM46,SELL,ANK2,BCAS1,SHTN1,USP16,URGCP,MADD,MSRA,PKNOX2,ARHGAP5,SLC8A2,MT3,SHANK2,SCMH1,ASCL1,SNAP25,ATP1A2,FYN,SOX1,MYT1L,ENKUR,NPAS3,BCL2L2,GFRA1,RGL1,RND1,ACSBG1,ABCC8,GLS,ADGRL3,WWC1,CACNA1A,GPM6B,TCF7L2,ZEB1,TCF12,NRGN,PTBP2,TMEM151B,PSD3,GRIA2,ADAMTS8,VWCE,TF,TMEM25,P2RX7,AIFM1,PAX6,TNR,HRH3,PDE1A,PDE1C,PDE2A,PDE4B,SCRG1,JAM2,NRXN2,SEMA5B,CP,POU3F2,TENM4,NKAIN4,VCAN,PRKCZ,CTNND1,MAPK8,ACY3,DPYSL5,PLPPR5,DNAJC6,ITGAV,PMEPA1,PTHLH,RGMA,PTPRE,PARD6A,SRGAP3,OLIG1,RAB5B,PID1,DNM2,SLC25A18,RASGRF1,RTN4,SLC6A15,CAMK1G,USH1C,RFX4,CACNG7,PIANP,SH3GLB1,PRRT4,RCAN2" Drug CID000446744 AC1L9K1W Stitch 8.44E-06 2.74E-01 9.41E-04 1.03E-02 10 45 "MAG,MBP,MOBP,MOG,FOLH1,NASP,GPM6B,OMG,POU3F4,L1CAM" Drug ctd:D010278 Parathion CTD 9.24E-06 3.00E-01 1.03E-03 1.13E-02 59 822 "EPS8,RIMKLA,ACHE,CDHR1,MBP,ADCY2,ADD3,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GRIN1,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug CID000003784 isradipine Stitch 9.42E-06 3.06E-01 1.04E-03 1.15E-02 15 100 "ASIC1,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,GAD2,CACNA1A,CACNA1E,CACNB2,ASIC3,KCNMA1,CACNG7" Drug 5903_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.50E-06 3.09E-01 1.05E-03 1.15E-02 21 179 "DPF1,ADD3,TUBB4A,SEMA6A,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,VAMP1,CDK5R2,ZEB1,PCDH9,PIK3CD,DNAJC12,MAPK8,DNAJC6,VWA5A" Drug CID000003413 forskolin from Coleus forskohlii Stitch 9.81E-06 3.19E-01 1.08E-03 1.18E-02 69 1014 "ASIC1,ACHE,ACLY,MBP,ADAR,ADARB2,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,TUBB4A,AGT,SCN3A,SCN4B,SCNN1D,FGF1,ACTL6B,ASIC4,FOXM1,SLC14A1,PDE8B,SCN3B,CPLX2,GFAP,SYT4,GNAS,NODAL,NPPA,CACNB2,PRLHR,AZIN2,NUMA1,GRIA1,GRM3,PTPN5,LEFTY2,USP2,GUCY1A2,ZFP91,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PDYN,CHGA,ASIC3,CHRM1,CHRNB2,PIK3CD,HPR,P2RY12,PTPA,PRKACB,CALY,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,TUBB2B,PTCH1,PTHLH,RAP1GAP,RET,RGS7,RGS10" Drug CID000024766 chondroitin sulfate Stitch 9.83E-06 3.19E-01 1.08E-03 1.18E-02 36 413 "MAG,F3,FABP7,FGF1,MOBP,MOG,SELL,BCAN,NLGN1,CSPG5,B3GAT1,B4GALNT1,NCAM1,GFAP,CNTN2,NEU4,OMG,TGFBR3,TNR,HMGB1,SERPINE2,SEMA5B,PLXNB3,CNTN1,COL9A2,ATCAY,VCAN,NCAN,SDC3,ARHGEF4,ITIH2,PTPRZ1,NTM,RTN4,L1CAM,OLIG2" Drug 2546_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "APC2,CEND1,EYA1,KIAA1109,CDC42BPA,ANK3,SORBS1,ATP1A3,PALLD,GNG4,GRIK2,SPX,KCNK10,PADI2,TNS1,NRXN2,RGS6,DZIP3,PRKCG,ARHGEF4,KCNJ10,TMCC2" Drug 4082_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "DPF1,ACTN2,ADORA1,PLA2G6,MOBP,PKP4,SLC14A1,SLCO1A2,TNIK,ADGRB2,GRM3,TNS1,PCDH9,PDE3B,CADM1,CNTN1,IFFO1,ARHGEF4,JAKMIP2,RABGAP1L,CRTAC1,RET" Drug 5077_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "ACHE,RTN1,FOXRED2,PLA2G6,GAS7,SLN,ASTN1,PHLDB1,NEUROD1,SLCO1C1,ADGRL3,ATF7,NUMA1,CDH8,CALY,CTNND2,PROX1,MASP1,ITIH2,KCND3,RGS7,RASGRP2" Drug ctd:D009020 Morphine CTD 1.05E-05 3.41E-01 1.14E-03 1.25E-02 38 448 "MAPT,SYT9,DSCAML1,ADORA1,TUBB4A,AGT,ASIC4,SELL,DOCK10,NTNG1,BCAS1,AQP4,RPH3A,ADGRA1,GAD2,ARPP21,NCAM1,GFAP,PHLDB1,GNAS,CAMK2A,GRIA1,GRIA2,GRIA4,GRIN1,GPR88,CCKBR,PDYN,HPCA,OPALIN,CCDC136,RGS6,CMTM5,PRKCG,IGSF1,AK5,SLC17A6,ST8SIA3" Drug CID000002821 CNQX Stitch 1.05E-05 3.42E-01 1.14E-03 1.25E-02 17 126 "SLC8A2,B3GAT1,SOX10,GAD2,CACNA1A,CACNB2,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,NTSR2,CHRM1,PTCH1" Drug CID000656979 O-Ln Stitch 1.07E-05 3.46E-01 1.15E-03 1.26E-02 11 56 "MAG,MBP,ERMN,MOG,GFAP,GFRA1,TJP1,ZFP91,PTPA,RBPJ,RET" Drug CID000447081 1m5b Stitch 1.08E-05 3.52E-01 1.16E-03 1.27E-02 5 9 "GRIA1,GRIA2,GRIA4,GRIK2,GRM3" Drug CID000100099 gamma-Glu-Gly Stitch 1.09E-05 3.53E-01 1.16E-03 1.27E-02 9 37 "GFAP,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,PDYN,GOPC" Drug ctd:D007608 Kainic Acid CTD 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "SFPQ,SLC1A2,SLC8A3,MT3,GAD2,NCAM1,GFAP,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,AIFM1,CDC42,PDYN,HPCA,CNRIP1,KCNQ2,LMO1,EN2" Drug 3366_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "MDM4,FOXRED2,KIAA1109,FOXG1,PDE8B,WDTC1,SOX10,LMO3,PHLDB1,OMG,NEURL1,CDH8,LILRA4,PDE4B,CHRNB2,POU3F2,SNCAIP,VCAN,MAPK8,PLPPR1,RAB3IL1,NUP214" Drug 3620_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "MAPT,FGF1,ASIC4,RASA3,SLC6A9,SNAP25,TNIK,NMNAT2,CPLX2,ALDH1L1,FGF17,VAMP1,BRSK2,USP2,POU3F4,PTAFR,SMG7,TMCC2,RAD52,DPP6,LMO1,VWA5A" Drug 3212_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "ARID1A,NDRG2,KIAA1109,ANK1,SLC2A5,PKNOX2,TAGLN3,ATP1A3,EMC1,ACSBG1,POPDC3,BTRC,WSCD1,CAMK2G,GUCY1A2,KIAA1549L,CHD5,ARHGEF4,NOS1AP,RIMS3,KCNK1,EFNA3" Drug 1535_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ADD3,TUBB4A,PPM1E,SYBU,ZNF365,FYN,ZCCHC24,RGL1,RND1,ACSBG1,VAMP1,ZEB1,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug 5987_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "DPF1,ADD3,TUBB4A,SORBS1,SYBU,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,EFNA3,VWA5A" Drug CID000006468 phencyclidine Stitch 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ACHE,FOLH1,SLC1A2,SLC14A1,DNER,NDUFA5,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,DAAM2,CHRNB2,HNRNPK,CRMP1,KCNT2,KCNA1,SLC25A18" Drug 6193_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ADD3,PPM1E,PALLD,ZCCHC24,ZSWIM8,NCAM1,RGL1,RND1,GPR19,PCDH9,RBFOX2,SERPINE2,NMT2,FEZ1,DZIP3,KIAA0513,RIMS3,DNAJC6,PARD6A,TMEM255A,EFNA3" Drug CID000005202 serotonin Stitch 1.15E-05 3.73E-01 1.18E-03 1.29E-02 44 554 "ACHE,ADAR,ADCY2,AGT,ACTL6B,API5,SLC1A2,SLC1A6,SLC1A7,B3GAT1,SNAP25,ATM,ATP1A2,ATP1A3,SOX10,GAD2,NPAS3,GFAP,ADHFE1,NUCB1,GRIN1,GRM3,TF,PAH,HPS5,HRH3,PRMT8,PDYN,CHGA,CHRM1,CHRNB2,HPR,P2RY12,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,KCNA6,SLC17A6,SLC6A15,RGS7,GPR61,EN2" Drug 1642_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "EMID1,FOXRED2,FHL1,FOXG1,C1orf61,CDC42BPA,ZCCHC24,NDUFA5,INKA2,ROBO3,NRGN,HAP1,FADS2,SULT4A1,PPP2R5C,MAPK8,EDRF1,PEX5,DSCAM,DTNA,VWA5A,LRRC23" Drug 4746_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "DPF1,MOBP,FOXG1,AMPH,ANK1,GAS7,RPH3A,SLC2A5,MSR1,MYH7,GLS,GNG3,GRIN1,TGFBR3,KCNK10,PCDH8,TPM3,GPR37L1,ATRNL1,MAPK10,STMN4,KCNMA1" Drug 4524_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MAPT,ACHE,ADORA1,ANK2,RASA3,SLN,CCDC181,GNG4,BTRC,GPM6B,GPR19,NEURL1,PDE4B,VCAN,CTNND2,PTAFR,PLPPR1,PRDM2,MAGI2,KCND3,RABGAP1L,RGS7" Drug 4347_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "FHL1,GAS7,SLC2A5,TAGLN3,DLL3,KIF21B,GLS,MYRF,CDK5R2,PRUNE2,CCKBR,PAX6,HPSE2,KIAA1549L,SULT4A1,POU3F4,ARHGEF4,MAPK8,PTPRO,KCNMA1,ST8SIA3,RASGRP2" Drug 6363_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "DPF1,ADCY2,C1orf61,ANK1,DOCK10,APC,SORBS1,RPH3A,PDE8B,MYBPC1,SOX10,PSD3,CELF3,PTGDR2,CA14,PIK3CD,SULT4A1,CNTN1,TENM4,RIMS3,PTAFR,PTCH1" Drug 425_DN staurosporine; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MAPT,NDRG2,GRAMD1B,PPM1E,ALDH4A1,WDTC1,NMNAT2,HAP1,HPS5,TMPRSS5,CHRM4,CCSER2,VAV2,NSD2,KIAA0513,SYTL2,DLG3,DSCAM,CAMK1G,VWA5A,EPB41L1,EPB41L2" Drug 4423_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "ARID1A,PLA2G6,FHL1,GAS7,RPH3A,PKNOX2,WDTC1,CADM3,EMC1,ALDH1L1,NEUROD1,AJAP1,GNAS,SERPINE2,FADS2,CNTN1,MICAL1,RIMS3,SYNC,RABGAP1L,ATN1,EN2" Drug 1546_UP Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MBP,CEND1,NDRG2,ADORA1,C1orf61,ITSN1,BCAN,GJB1,CACNA1A,NPPA,NRGN,OMG,LILRA4,DUSP26,CAMKV,COL9A2,PRRX1,PACSIN1,TMCC2,CAMK1G,NUP214,ARHGEF10L" Drug 4370_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "FABP7,AGT,FHL1,CDC42BPA,APC,GAS7,SLC1A7,SLC2A5,CSPG5,TAGLN3,AJAP1,GPM6B,GUCY1A2,P2RX7,SEZ6L,JAM2,PIK3CD,SULT4A1,RAD52,SSPN,LMO1,ELAVL3" Drug 5758_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "PRR5L,TUBB4A,HPCAL4,FOXG1,APBB1,ATP1A2,ATP2B2,AJAP1,VAMP1,SEMA4A,PRUNE2,CAMK2A,BRSK2,PLEKHB1,PRDM2,PTPRD,SV2A,RABGAP1L,DNAH9,PAK5,EFNA3,VWA5A" Drug CID000001370 1-BCP Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000107978 beta-N-oxalylaminoalanine Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000063114 AC1L1YEG Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000129091 5-h PCA Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID003038472 irampanel Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011334126 CHEBI:570577 Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000656707 LY395153 Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID003005587 thioformamide Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "F3,ABCC8,PMP2,ABCC9" Drug CID000065740 Chicago acid Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug 5017_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-05 3.99E-01 1.20E-03 1.31E-02 21 182 "ADD3,TUBB4A,SORBS1,CCDC88A,DNAH17,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,NRGN,TGFBR3,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,TMCC2,EFNA3" Drug CID000005673 AC1Q646P Stitch 1.27E-05 4.14E-01 1.20E-03 1.31E-02 10 47 "PDE8B,PDE1A,PDE1C,PDE2A,PDE4B,POU3F2,KCNA1,KCNA2,KCNA6,KCNQ2" Drug 5960_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "PLA2G6,MOBP,SELL,AMPH,SLC2A5,DNAH17,ALDH4A1,ADGRB2,NEUROD1,VAMP1,GNG4,CDK5R2,ZEB1,PADI2,PTGDR2,POU3F4,MAPK8,AK5,RAP1GAP,RGS10,LPAR6,ROM1" Drug 3063_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CHST15,SEMA6A,AQP4,SLN,CCDC181,PALLD,DKK3,ARPP21,NAP1L2,NPPA,ATP13A2,TGFBR3,CDH10,CHI3L2,JAM2,ZFYVE9,FLRT1,RGS6,KCNC1,RASGRF1,RGS7,EPB41" Drug 4653_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "TTYH1,ABAT,MOBP,C1orf61,SELL,APC,AQP4,SNAP25,SOX10,GPM6A,GRIN1,USP2,CDH10,CHI3L2,HPCA,SLC22A6,NRXN2,RGS6,KCND3,AK5,ARNT2,VWA5A" Drug 6011_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MAPT,ADORA1,MOBP,AMPH,RASA3,RPH3A,BRINP2,WDTC1,ZCCHC24,NCAM1,GFAP,CDH10,HRH3,PDE3B,CHRNB2,CAMKV,PTAFR,ELMO1,KCND3,ATN1,CAMK1G,ST8SIA3" Drug 2186_UP Evoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "PLA2G6,MOBP,ANK3,SLC1A7,SHANK2,SOX10,FGF17,NEUROD1,VAMP1,CAMK2A,NEURL1,PTGDR2,GPR37L1,ASIC3,DUSP26,FLRT1,PARD6A,KCND3,PEX5,PAK5,ABCC9,CAMK1G" Drug 6367_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "KIAA1109,FHL1,C1orf61,ANK1,APC,NTNG1,RPH3A,SLC2A5,SHANK2,DNAH17,NPAS3,PHLDB1,PSD3,TNS1,HRH3,PIK3CD,SULT4A1,VAV2,CALY,MAPK8,MASP1,OLIG2" Drug 2674_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "FABP7,FHL1,ALDH4A1,B3GALT2,CADM3,GAD2,NCAM1,MYRF,TGFBR3,DAAM2,PCDH9,HPSE2,NRXN2,DZIP3,MAPK10,PROX1,RIMS3,DNAJC6,KCND3,ABI2,LPAR6,LRRC23" Drug 4737_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CEND1,KIAA1109,PLA2G6,MOBP,CDC42BPA,ASCL1,ATP1A2,SPART,ALDH1L1,NEUROD1,AJAP1,ACSBG1,GNG3,OPCML,PDE4B,CHRNB2,VAV2,RIMS3,PTHLH,KCND3,ATN1,VWA5A" Drug 3678_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MAPT,ASTN1,SCN3B,ZSWIM8,NPAS3,ALDH1L1,INKA2,RND1,GPM6A,GRIK2,NEURL1,TNS1,PTGDR2,CHI3L2,FLRT1,CRMP1,EDRF1,TOX,RIMS3,RABGAP1L,ARNT2,DTNA" Drug 2324_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ADORA1,PLA2G6,FGR,CDC42BPA,APC,BCAN,SLC2A5,PKNOX2,SORCS3,ATP2B2,INKA2,POPDC3,PSD3,PTGDR2,ZMYND8,SCRG1,SNCAIP,MAPK8,KCND3,TMCC2,NUP214,RGR" Drug 3112_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "SYNDIG1,ACTN2,ARID1A,RYR1,FOXG1,NTNG1,SLC14A1,ALDH4A1,LMO3,BCL2L2,PRUNE2,GPM6A,MAGI1,TMPRSS5,CCSER2,VAV2,MASP1,RIMS3,PEX5,ATN1,SIDT2,LRRC23" Drug 3117_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ABAT,GRAMD1B,CDC42BPA,ANK3,GPR153,CCDC181,GAD2,RAP1GAP2,WWC1,GPM6A,CACNB2,GUCY1A2,PADI2,PDE1C,ARHGEF4,MAPK8,ECE2,SYNC,KCNMA1,KCNN3,PAK5,ROM1" Drug 3350_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "NDRG2,F3,KIAA1109,APBA2,GAS7,AQP4,SLC1A2,ASCL1,SLN,CPLX2,TLL2,KCNK10,DAAM2,PCDH9,CDH8,PDE3B,CHRNB2,PIK3CD,PACSIN1,KCNJ4,KCNMA1,RAB3IL1" Drug 3621_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "SYNDIG1,RYR1,AGT,RASA3,ASCL1,GAD2,ACSBG1,ROBO3,GPM6A,CRB1,KCNK10,PTGDR2,NCAN,PKN2,RIMS3,PARD6A,KCND3,SRGAP3,KCNK2,ATN1,RASGRF1,RASGRP2" Drug 2305_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MDM4,NDRG2,CDC42BPA,SLC6A9,DNAH17,ASPH,SOX10,GFAP,KAZN,CAMK2G,CELF3,TNS1,SEZ6L,CHRNB2,SERPINE2,FADS2,PTAFR,RABGAP1L,RASGRF1,L1CAM,NUP214,SEC61A2" Drug 6054_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "DPF1,SYNDIG1,AGT,FGF1,FHL1,APBA2,SHANK2,ATP2B2,ZCCHC24,NEUROD1,NPPA,DAAM2,HPSE2,RGS6,NCAN,SDC3,KCND3,KCNJ4,PARP11,DPP6,ST8SIA3,TTLL7" Drug 5045_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CEND1,RYR1,PDE8B,CADM3,GAD2,PHLDB1,BTRC,ADGRL3,PRUNE2,CRB1,TPM3,PDE3B,PDE4B,SPATA6,FEZ1,MAPK10,PROX1,ITIH2,RAD52,DTNA,ST8SIA3,RGS10" Drug 2351_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ACTN2,FOXRED2,SCN3A,RASA3,NLGN1,ZNF365,ALDH4A1,ATP1A3,ARPP21,NDUFA5,VAMP1,GNG3,CACNA1A,REPS2,PDE1C,CRMP1,SYTL2,PTAFR,SV2A,PEX5,SSPN,RASGRP2" Drug 6179_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.34E-05 4.35E-01 1.22E-03 1.34E-02 21 183 "ADD3,TUBB4A,TESK2,ALDH4A1,PALLD,ZSWIM8,NCAM1,RGL1,RND1,GLS,CAMSAP2,ATP13A2,INA,PADI2,PCDH9,KIAA0513,RIMS3,DNAJC6,PARD6A,TMEM255A,EFNA3" Drug 6192_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "APC2,ARID1A,RYR1,ADORA1,FHL1,HPCAL4,ANK3,SHANK2,ALDH4A1,GFRA1,INKA2,PHLDB1,DAAM2,TNS1,PTGDR2,TMPRSS5,CHI3L2,CHRM4,CTNND2,ATN1,ABCC9,ROM1" Drug 6139_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,RYR1,CDC42BPA,ANK2,GPR153,SNAP25,NEUROD1,SLCO1C1,WWC1,WSCD1,GRM3,ATP13A2,CELF3,MAGI1,CHRM4,NECAB2,POU3F2,PLPPR4,SV2A,ABCC9,RGR,EFNA3" Drug 6611_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,FOXG1,SELL,APC,GAS7,SHANK2,NPAS3,SPART,ALDH1L1,RND1,GNG4,BTRC,OMG,CDH8,ARHGAP22,SPATA6,FEZ1,VCAN,RIMS3,ARNT2,DLG3,VWA5A" Drug 5797_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,ACTN2,ANK2,NTNG1,SLN,TNIK,NCAM1,MYRF,BTRC,NPPA,DAAM2,CDH8,LILRA4,PDE3B,ZMYND8,FAM131B,MASP1,RABGAP1L,NAV2,SLC17A6,NUP214,ELAVL3" Drug 5207_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,APC,BCAN,AQP4,SNAP25,SOX10,BCL2L2,RGL1,PHLDB1,OPCML,USP2,GUCY1A1,SDC3,MAPK8,PTHLH,PARD6A,RAB3IL1,ATN1,SSPN,SIDT2,ELAVL3,EN2" Drug 2293_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "AMPH,GAS7,BCAN,DNAH17,TAGLN3,ATP2B2,TNIK,NMNAT2,POPDC3,BTRC,WSCD1,GPM6A,CCKBR,PTGDR2,TPM3,PDE4B,FADS2,SF1,NCAN,KCND3,SLC17A6,EN2" Drug 6255_UP Spironolactone [52-01-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAG,CDHR1,CDC42BPA,ANK3,APC,SLC6A9,PDE8B,SOX10,EMC1,NDUFA5,SEMA4A,BTRC,CAMK2G,OMG,GUCY1A2,SEZ6L,HPSE2,MAPK8,SYNC,JAKMIP2,DTNA,EFNA3" Drug 6363_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,EXTL1,ARID1A,HPCAL4,ANK2,APBA2,B3GALT2,EMC1,ACSBG1,POPDC3,GNG3,GPM6B,NPPA,ZEB1,HAP1,USP2,PIK3CD,ETNPPL,EDRF1,PROX1,STMN4,KCNA2" Drug 5904_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "KCNIP2,ADORA1,FGR,SLC1A7,CADM3,COLGALT2,PHLDB1,RND1,TMEM151B,CCKBR,USP2,INA,KCNK10,SEZ6L,TMPRSS5,SULT4A1,VAV2,MAPK10,RIMS3,PLPPR1,ITIH2,RASGRP2" Drug 4764_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ASIC1,EMID1,FHL1,C1orf61,PDE8B,CSPG5,KIF21B,POPDC3,GNG3,TCF7L2,DAAM2,CDC42,CHI3L2,ASIC3,VAV2,CRMP1,VCAN,MAPK8,SYNC,TMCC2,KCNMA1,NKAIN1" Drug 2811_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACTN2,RYR1,FOXG1,RASA3,NLGN1,SLC1A2,SLC6A9,CADM3,EMC1,RND1,GLS,SEMA4A,CACNB2,ZEB1,CAMK2G,KCNK10,CDC42,ASIC3,PTPRO,RAB3IL1,DTNA,VWA5A" Drug 4218_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACHE,RASA3,AQP4,SLC1A6,ASCL1,ATP1A2,NCAM1,INKA2,VAMP1,ADAMTS8,CRB1,USP2,TLL2,SEZ6L,PRMT8,GPR37L1,IGSF1,MAPK8,KCNJ9,RASGRF1,EPB41,RASGRP2" Drug 3824_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACTN2,RTN1,FOXG1,RND1,NEURL1,PADI2,PDE3B,CHI3L2,MED1,RGS6,IGSF1,PROX1,MAGI2,SMG7,SRGAP3,DLG2,RAB3IL1,ATN1,RASGRF1,ABCC9,RET,VWA5A" Drug 5763_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,ADCYAP1R1,TUBB4A,FOXG1,C1orf61,APBB1,BCAS1,TAGLN3,BRINP2,SORCS3,SCN3B,NDUFA5,P2RX7,DAAM2,NRXN2,MICAL2,ARHGEF4,MAPK10,ITIH2,DTNA,ABCC9,VWA5A" Drug 4261_UP Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACHE,NDRG2,ANK1,B3GALT2,MYH7,NEUROD1,SLCO1C1,VAMP1,NUMA1,SPX,LILRA4,HPSE2,HPCA,ARHGEF4,PRDM2,KCNC1,KCND3,KCNH1,NTM,KCNJ9,ATN1,ABCC9" Drug 5615_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAG,KIAA1109,ASIC4,ITSN1,GAS7,ZSWIM8,PHLDB1,RND1,GLS,PRUNE2,GPM6A,HAP1,OMG,PTGDR2,CRMP1,VCAN,MAPK8,MAPK10,NOS1AP,MASP1,KCNA2,RABGAP1L" Drug 3342_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,CDHR1,KCNIP2,SEMA6A,FHL1,MOBP,GAS7,BCO1,MSR1,TAGLN3,BRINP2,SORCS3,GNAS,HAP1,PDE4B,CHI3L2,ZFYVE9,VAV2,VCAN,RIMS3,PTHLH,ST8SIA3" Drug 2557_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,ACTN2,MOBP,RASA3,PKP4,TAGLN3,TNIK,RAP1GAP2,MYRF,PRUNE2,GPM6B,GPR19,NUMA1,PSD3,ZFYVE9,CNTN1,PKN2,EDRF1,SLC17A6,CAMK1G,RET,RASGRP2" Drug 2714_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MBP,ACTN2,PLA2G6,CDC42BPA,GAS7,ZNF365,TNIK,FGF17,BTRC,KLHL4,TGFBR3,PDE1C,PRMT8,TMPRSS5,VAV2,BEST1,KLK6,KIAA0513,CAB39L,SUSD4,EFNA3,RASGRP2" Drug 1499_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "EMID1,ACTN2,NDRG2,F3,APC,BCAS1,TAGLN3,ALDH4A1,SOX10,ADGRB2,ASTN2,BTRC,CAMK2G,NUMA1,PRMT8,CCSER2,MICAL1,SDC3,TMCC2,DTNA,ROM1,LRRC23" Drug 3371_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ASIC1,APC2,ADORA3,PLA2G6,FOXG1,SORBS1,SLCO1A2,TAGLN3,SLN,SORCS3,SOX10,GPM6A,ATF7,PIK3CD,SULT4A1,PLCH2,PROX1,PTAFR,ITIH2,KCND3,SRGAP3,SLC6A15" Drug ctd:C005460 uranyl acetate CTD 1.42E-05 4.61E-01 1.23E-03 1.35E-02 26 258 "ACHE,NDRG2,ADAR,SLC44A5,APBB1,APC,NSG2,KIF1B,ABCC8,KAZN,TNFRSF1B,PDE1A,HMGB1,CHRM1,CHRNB2,C11orf49,MFSD4A,CRLS1,SDC3,PUM1,DPYSL5,TOMM20,CSDE1,PLEKHB2,DTNA,BAALC" Drug CID000002482 butamben Stitch 1.43E-05 4.64E-01 1.23E-03 1.35E-02 6 15 "CACNA1A,CACNA1E,KCNA1,KCNC1,KCND3,L1CAM" Drug CID000031657 Vydate Stitch 1.43E-05 4.64E-01 1.23E-03 1.35E-02 6 15 "ACHE,FOLH1,SHANK2,DDR1,PTPN5,HPR" Drug CID000002818 clozapine Stitch 1.47E-05 4.77E-01 1.24E-03 1.36E-02 27 274 "SERPINA3,ADAR,SLC1A2,NRG3,NPAS3,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRIN1,GRM3,AIFM1,HRH3,PDE4B,NTSR2,CHGA,CHRM1,CHRNB2,CALY,PRKCG,PKN2,PRKCZ,SLC17A6,DTNA,SSPN,OLIG2" Drug 5079_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ASIC1,ACTN2,MDM4,PLA2G6,BBOX1,ANK1,SLN,KIF21B,PHLDB1,NEUROD1,ADGRL3,PRUNE2,USP2,SEZ6L,LILRA4,MAGI1,CRMP1,VCAN,PROX1,PID1,DSCAM,RGS10" Drug 2737_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FHL1,BBOX1,CDC42BPA,ANK3,NLGN1,SLC6A9,ATP1A3,PALLD,ACSBG1,GRIN1,GUCY1A1,SEZ6L,ARHGEF4,PHYHIP,STMN4,KCNC1,KCND3,SRGAP3,FAM13C,ST8SIA3,RGR,EPB41" Drug 6364_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,EXTL1,ARID1A,HPCAL4,MOBP,SLC1A7,ASPH,B3GALT2,CADM3,EMC1,CPLX2,ADGRB2,ACSBG1,MYRF,GPM6B,PROX1,PTHLH,STMN4,KCNA2,ATN1,RGS10,ELAVL4" Drug 4501_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "DPF1,EMID1,ADCY2,RYR1,PLA2G6,C1orf61,TRIM46,BCAS1,SLC1A7,SLC2A5,PKNOX2,SEMA4A,GNG3,KLHL4,NEURL1,TNS1,CDH8,PDE4B,VAV2,MAGI2,RABGAP1L,ST8SIA3" Drug 5542_DN Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "SERPINA3,APC,BCAS1,SLC1A7,PDE8B,ZCCHC24,NUCB1,ATP13A2,TGFBR3,TPD52,PDE3B,PTPA,CTNND2,SMG7,DLG3,RAD52,RGS10,EFNA3,ABI2,ROM1,EPB41L1,EPB41L2" Drug 2285_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "CDC42BPA,SLC2A5,BRINP2,ATP2B2,SOX10,NDUFA5,GPR162,ATF7,NPPA,PSD3,OMG,USP2,SEZ6L,VAV2,VCAN,MAPK8,NOS1AP,PTAFR,KCNC1,KCNMA1,ATN1,CRTAC1" Drug 4220_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FOXRED2,C1orf61,RASA3,PKNOX2,ASCL1,ATP1A2,GJB1,USP2,P2RX7,TNS1,PTGDR2,GPR37L1,NRXN2,CABP1,RGS6,NOS1AP,PRDM2,KCNA2,KCNH1,ABCC9,ST8SIA3,EPB41" Drug 4068_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAG,ACTN2,RYR1,HPCAL4,MOBP,SORBS1,SLCO1A2,NFASC,AJAP1,VAMP1,CDK5R2,OLR1,PDE2A,TMPRSS5,NRXN2,PIK3CD,SULT4A1,CHD5,KCNJ4,KCNJ9,DSCAM,USH1C" Drug 3777_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "CEND1,SELL,DOCK10,BCAN,SLC14A1,PDE8B,SCN3B,RND1,SLCO1C1,GNG4,GRIK2,TPM3,HPSE2,ZFYVE9,KIAA1549L,MAPK10,TOX,ATN1,DSCAM,DTNA,RGS10,ELAVL3" Drug 2320_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MOBP,CDC42BPA,BCAN,SLC1A7,BCO1,SLCO1A2,B3GAT1,ZSWIM8,GLS,CACNA1A,NPPA,CHRNB2,POU3F4,VCAN,SDC3,PTCH1,PTHLH,ITIH2,KCND3,TMCC2,DTNA,RAVER2" Drug 3883_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,SEMA6A,ANK1,AQP4,SLC6A9,ASCL1,ATM,ZSWIM8,MYH7,GLS,ROBO3,PRUNE2,CHI3L2,ZFYVE9,NECAB2,SNCAIP,PTAFR,PTHLH,ITIH2,CNIH3,L1CAM,RASGRP2" Drug 5078_UP Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EMID1,MOBP,ANK1,NLGN1,AQP4,CCDC181,VAMP1,GNG3,GRIN1,ADAMTS8,INA,PDE4B,JAM2,ST8SIA5,NOS1AP,TOX,PRDM2,KCNA2,KCNC1,RAD52,SLC6A15,VWA5A" Drug 3707_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EYA1,FABP7,ANK1,NLGN1,RPH3A,SLC1A7,DKK3,LMO3,ACSBG1,KAZN,GPR19,PADI2,TNS1,TPM3,PRMT8,CA14,IGSF1,NOS1AP,PROX1,MAGI2,DTNA,ST8SIA3" Drug 4201_UP Atovaquone [95233-18-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "NDRG2,HPCAL4,PKP4,SNAP25,CADM3,BTRC,HAP1,OLR1,OMG,PTGDR2,MAGI1,CAMKV,SPATA6,PLCH2,PTAFR,PLPPR1,AK5,ARNT2,SLC17A6,DTNA,VWA5A,ROM1" Drug 6713_UP Monobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EMID1,MOBP,FOXG1,PKP4,APC,NTNG1,RPH3A,ATP1A3,ATP2B2,SOX10,NEUROD1,CACNA1A,GPM6A,GRIK3,PC,FEZ1,CTNND2,KCND3,SRGAP3,CRTAC1,VWA5A,EPB41" Drug 3762_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "APC2,FGF1,PKP4,SLC1A2,MSR1,TAGLN3,ATP1A2,RND1,ACSBG1,VAMP1,OMG,INA,PDE2A,JAM2,SPATA6,POU3F4,MASP1,PTPRO,SRGAP3,ARNT2,NKAIN1,RET" Drug 5408_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ARID1A,ADORA1,MOBP,FOXG1,GAS7,BCAN,SLC2A5,PHLDB1,NEUROD1,RND1,GPM6A,CAMK2G,OMG,OPCML,CDH10,PDE3B,SERPINE2,MAPK8,SYNC,PTHLH,KCNC1,KCND3" Drug 3674_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,ADCY2,C1orf61,SELL,RASA3,NTNG1,MSR1,SLCO1A2,BRINP2,ALDH4A1,SNAP25,ADGRB2,VAMP1,MYRF,GRIN1,GRM3,NEURL1,PDE3B,DUSP26,SULT4A1,SNCAIP,ELAVL4" Drug 6524_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,ACTN2,TUBB4A,FHL1,GAS7,URGCP,SLN,MYH7,COLGALT2,ALDH1L1,NDUFA5,FGF17,CACNB2,CAMK2G,PSD3,USP2,HRH3,ZMYND8,PLEKHB1,IFFO1,DTNA,EFNA3" Drug 6394_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FOXG1,ANK1,DOCK10,SORBS1,MSR1,ASCL1,SLCO1A2,ATP2B2,KIF21B,COLGALT2,GFAP,WSCD1,GDAP1L1,MICAL2,PLCH2,DNAJC6,ITIH2,ELMO1,PRDM2,KCNMA1,ATN1,CAMK1G" Drug 2689_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ABAT,MOBP,C1orf61,ANK3,RPH3A,SNAP25,ATP1A3,CADM3,BRSK2,GRIK2,ADAMTS8,CRB1,NEURL1,CDH10,GPR37L1,PHKG1,NMT2,FLRT1,CABP1,STMN4,RASGRF1,ST8SIA3" Drug CID000023982 gadolinium Stitch 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ASIC1,MBP,ADGRV1,RYR1,ASIC4,ST8SIA1,MTR,B4GALNT1,GFAP,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,AIFM1,KCNK10,TNFRSF1B,KCNK2,CACNG7" Drug CID005282252 NS 102 Stitch 1.55E-05 5.03E-01 1.25E-03 1.38E-02 7 22 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000121892 retigabine Stitch 1.55E-05 5.04E-01 1.25E-03 1.38E-02 10 48 "ABAT,ANK3,ARFGAP1,CHRNB2,KCNA1,KCNA2,KCNC1,SV2A,NTM,KCNQ2" Drug CID000000191 arabinosyladenine Stitch 1.59E-05 5.15E-01 1.28E-03 1.40E-02 55 762 "ADAR,F3,ADARB2,ADCY2,RYR1,ADORA1,ADORA3,ACTL6B,APC,MADD,PDE8B,SLCO1A2,ATP1A2,ATP1A3,ATP2B2,MYBPC1,AHCYL1,GART,ABCC8,GNAS,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,GRIA2,GRIA4,GRIK2,GRM3,GUCY1A2,P2RX7,GUCY1A1,RBFOX2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,PIK3CD,UBTF,P2RY12,ATCAY,PTPA,PRKACB,PRKCG,PKN2,PRKCZ,PLPPR5,AK5,KCNMA1,PYGM,DPP6,ABCC9,LPAR6" Drug 2558_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "ACTN2,CDC42BPA,RASA3,PKP4,SLC6A9,ARHGAP5,ASCL1,ASPH,SPART,INA,PTGDR2,PDE3B,CHRNB2,ZFYVE9,FLRT1,VCAN,PRKCZ,CNIH3,TMCC2,NAV2,DTNA,LPAR6" Drug 4995_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "FHL1,ANK3,PDE8B,ALDH4A1,WDTC1,INKA2,GLS,GNAS,GPM6B,CCKBR,KCNK10,CHRNB2,CAMKV,VAV2,CNTN1,ARHGEF4,MAPK8,SV2A,ATN1,TTLL7,VWA5A,LRRC23" Drug 4242_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "RTN1,SELL,PKP4,APBB1,PKNOX2,ATP2B2,TNIK,RND1,AJAP1,CACNB2,HAP1,OLR1,PDE3B,SLC22A6,SULT4A1,NCAN,PARD6A,KCND3,DNAH9,RAD52,DTNA,RAVER2" Drug 2409_UP Bumetanide [28395-03-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "FOXG1,ANK3,DOCK10,APC,SORBS1,TAGLN3,SNAP25,ZCCHC24,CADM3,RAP1GAP2,GLS,CACNA1A,GRIK2,TGFBR3,REPS2,TNS1,SERPINE2,CAMKV,MAPK8,PTPRD,DSCAM,FAM13C" Drug CID000003331 felbamate Stitch 1.84E-05 5.98E-01 1.47E-03 1.61E-02 12 70 "ABAT,ADGRV1,GAD2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,PTCH1" Drug CID000001779 "5,7-dichlorokynurenic acid" Stitch 1.88E-05 6.11E-01 1.49E-03 1.64E-02 10 49 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TPM3,PTPA,SLC25A18" Drug 5594_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.91E-05 6.21E-01 1.52E-03 1.66E-02 20 173 "ADD3,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,SRGAP3,VWA5A" Drug CID000120739 G 3012 Stitch 1.96E-05 6.36E-01 1.55E-03 1.70E-02 17 132 "SEMA6A,SEMA6C,NTNG1,LRRC4C,SLC14A1,SLIT1,FYN,NKX2-2,SEMA4A,ROBO3,UNC5D,CNTN2,HMGB1,RGMA,RTN4,L1CAM,EFNA3" Drug 6609_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.08E-05 6.76E-01 1.64E-03 1.80E-02 20 174 "ABAT,CEND1,SORBS1,ATP1A3,FYN,GAD2,RGL1,RND1,GLS,VAMP1,DNAJC12,VCAN,PROX1,KIAA0513,SYTL2,DNAJC6,PLPPR4,PID1,RGS7,EFNA3" Drug CID000131938 LY235959 Stitch 2.11E-05 6.86E-01 1.66E-03 1.82E-02 8 31 "FOXM1,SLC1A2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000005365 4-methylglutamic acid Stitch 2.11E-05 6.86E-01 1.66E-03 1.82E-02 8 31 "SLC1A2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000000764 guanine Stitch 2.14E-05 6.93E-01 1.67E-03 1.83E-02 62 903 "EPS8,RTKN,ADAR,ADARB2,ADCY2,ADORA1,ADORA3,TUBB4A,SELL,RASA3,PKP4,APC,MADD,PDE8B,ARFGAP1,NMNAT2,GART,RGL1,NEUROD1,RND1,GNAS,GNG3,GNG4,CACNA1E,DIRAS1,GRIA1,GRIA2,GRIA4,GRID1,RFFL,GRIK4,GRM3,CCKBR,P2RX7,CDC42,MAGI1,PDE2A,IGFN1,CHRM1,VAV2,PMP2,P2RY12,RGS6,PRKACB,CTNND1,MAPK8,MAPK10,MASP1,TUBB2B,PRTFDC1,RAB5B,RALGDS,ABI1,RASGRF1,GNE,USH1C,RGS7,ARHGEF10L,EEF1A2,LPAR6,BSCL2,RASGRP2" Drug 2904_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.19E-05 7.11E-01 1.71E-03 1.88E-02 21 189 "PRR5L,NDRG2,FHL1,ASRGL1,ARHGAP5,PALLD,TNIK,NCAM1,RGL1,CAMSAP2,ZEB1,GPR19,INA,PCDH9,FEZ1,RIMS3,DNAJC6,MAGI2,TMEM255A,TTLL7,SIDT2" Drug ctd:D008731 Methoxychlor CTD 2.20E-05 7.14E-01 1.71E-03 1.88E-02 43 551 "MAG,MBP,MEG3,AMPH,SFPQ,ITSN1,DGKZ,SLC1A2,SLC1A6,SLC8A2,ATP1A2,FYN,KIF1B,NFIA,SYT4,GNAS,CACNA1A,ACSL6,CACNB2,HAP1,GRIA2,GRIN1,GRM3,PTPN5,PDE2A,PDYN,CHGA,PHKG1,CP,MED1,SDC3,MAPK8,MAPK10,SIRPA,MAGI2,KCNA2,KCNA4,KCNC1,KCNMA1,DLG3,SLC17A6,DPP6,RALGDS" Drug 3746_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.26E-05 7.35E-01 1.75E-03 1.92E-02 20 175 "ABAT,MAPT,TUBB4A,FYN,TNIK,NFASC,RGL1,RND1,HAP1,USP2,PCDH9,PDE2A,PIK3CD,DNAJC12,RIMS3,SYTL2,DNAJC6,PLPPR4,EFNA3,VWA5A" Drug 4436_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.26E-05 7.35E-01 1.75E-03 1.92E-02 20 175 "ABAT,MAPT,BRINP2,FYN,RGL1,GLS,HAP1,USP2,PCDH9,CADM1,DNAJC12,KIAA0513,RIMS3,SYTL2,PTAFR,PTCH1,DNAJC6,JAKMIP2,PLPPR4,VWA5A" Drug CID000001271 L-CCG-I Stitch 2.27E-05 7.37E-01 1.75E-03 1.92E-02 10 50 "ADORA1,SLC1A2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,KCNMA1,SLC17A6" Drug ctd:C487081 belinostat CTD 2.29E-05 7.43E-01 1.77E-03 1.94E-02 50 679 "MAP6,IL17D,RTN1,CHST15,ELMOD1,SOX6,USP28,DOCK10,SESN3,SFMBT2,LRRC55,SCG3,SLIT1,ASTN1,SNAP25,TNIK,DNER,LMO3,COLGALT2,SMOC1,GFRA1,ADGRL3,ZEB1,AKNA,CCKBR,CRB1,SPX,PTPN5,PCDH8,LGI1,ADGRG1,CHGA,NLGN3,GDAP1L1,KIAA1549L,NRXN2,NEGR1,CNTN1,NCAN,PLD5,ARHGEF4,HES5,ANKS1B,MAGI2,OLFM3,RABGAP1L,ARNT2,SSPN,LPAR6,SEZ6" Drug ctd:C006703 benzo(b)fluoranthene CTD 2.30E-05 7.45E-01 1.77E-03 1.94E-02 95 1564 "SERPINA3,ZFYVE27,RIMKLA,EMID1,RCSD1,MEG3,ADGRV1,LDLRAD3,RTKN,MDM4,F3,PLEKHG5,ADCYAP1R1,ADD3,ERMN,ADORA3,FGF1,SEMA6A,GOLGA7B,HPCAL4,SELL,ANK3,ANXA7,MAGI3,ZNF365,RUFY2,MSR1,NSG2,CGREF1,ARFGAP1,ASPH,SLN,DDX25,PALLD,SCN3B,ADAM15,CPLX2,GPR162,INKA2,GJB1,RND1,SEPT3,KAZN,MMD2,PSRC1,TCF7L2,TCF12,NRDC,NRGN,HAP1,CAMK2G,TF,PTPN5,TMEM25,USP2,MFSD2A,P2RX7,TIE1,TNS1,PDE2A,CIART,ZMYND8,HMGB1,CA14,LRTM2,PFKFB3,MS4A7,TMEFF2,ARHGAP22,ANLN,CPT1C,CELF5,CP,FEZ2,MICAL2,OSBPL3,FMN2,MAPK10,NOS1AP,FGFR1OP2,TUBB2B,KCNH1,OLIG1,TMEM255A,FAM57B,RAP1GAP,SUSD4,FAM13C,TTLL7,SYT15,SSPN,PIANP,LPAR6,BSCL2,EPB41" Drug ctd:C076029 olanzapine CTD 2.45E-05 7.96E-01 1.88E-03 2.06E-02 16 121 "SERPINA3,AQP4,PDE8B,SNAP25,GAD2,CAMK2A,GRIA2,DCLK1,PDE1A,CHRM1,CP,NCAN,ITIH2,KCNA1,RTN4,RGS7" Drug 4565_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.46E-05 7.99E-01 1.88E-03 2.07E-02 20 176 "ABAT,TESK2,SH3GL2,SORBS1,TAGLN3,FYN,TNIK,ADGRB2,RGL1,RND1,GLS,HAP1,TGFBR3,USP2,REPS2,DNAJC12,KIAA0513,PTCH1,DNAJC6,PLPPR4" Drug CID000004587 AC1NFC6P Stitch 2.48E-05 8.07E-01 1.90E-03 2.08E-02 18 148 "MAG,MBP,MOBP,BCAN,MSRA,ASCL1,NCAM1,GFAP,FGF17,PCDHGA3,PAX6,TNR,CDH8,HEPACAM,PMP2,OLIG1,EN2,OLIG2" Drug 5917_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MDM4,RYR1,ADORA1,ZNF365,ALDH4A1,FYN,NMNAT2,EMC1,ATF7,GRM3,CDC42,CNTN1,ATRNL1,EDRF1,PTPRE,KCNJ4,TMCC2,NAV2,RAD52,EFNA3,VWA5A" Drug 2955_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "SYNDIG1,ADORA3,FGR,AMPH,CDC42BPA,NTNG1,BCAS1,GPR153,TAGLN3,NPAS3,ALDH1L1,PADI2,UBTF,NMT2,ST8SIA5,DZIP3,ZBTB16,SMG7,DLG3,SEC61A2,EFNA3" Drug 497_UP 2-propylpentanoic acid; Up 200; 1000uM; ssMCF7; HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MAPT,NDRG2,FHL1,PPM1E,SNAP25,FYN,ZCCHC24,NMNAT2,B4GALNT1,ADGRB2,SPART,WSCD1,NRGN,CAMK2A,ATP13A2,DNAJC12,MICAL1,ECE2,SUSD4,TTLL7,EFNA3" Drug 3058_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MAPT,APC2,ACTN2,WLS,NDRG2,SEMA6A,ASCL1,TNIK,RGL1,CAMSAP2,ATP13A2,REPS2,PCDH9,DZIP3,KIAA0513,RIMS3,DNAJC6,PTHLH,TMEM255A,RASGRF1,EPB41" Disease C0036341 Schizophrenia DisGeNET Curated 1.20E-21 7.62E-18 7.62E-18 7.11E-17 156 1561 "MAG,SERPINA3,MAP6,ACHE,MBP,LGR4,RTN3,SYNDIG1,CSMD2,ADCYAP1R1,FABP7,ADORA1,PLA2G6,MOBP,MOG,SOX6,ANK3,FOLH1,APBA2,APC,NTNG1,DGKZ,BCAN,NLGN1,AQP4,SLC1A2,ZNF365,SLC1A6,MSRA,PKNOX2,SLC6A9,SHANK2,ASCL1,GPR153,CSPG5,MTR,ASTN1,B3GAT1,SNAP25,ATM,SNCB,NRG3,FYN,DKK3,GABBR1,MYT1L,TNIK,SOX5,SOX10,GAD2,CPLX2,FXYD6,NPAS3,NFASC,NCAM1,LMO3,GFAP,GFRA1,NEUROD1,MLC1,ARHGEF7,GLS,VAMP1,ASTN2,GNAS,WWC1,GPM6A,ACSL6,DDR1,CACNB2,TCF7L2,NRGN,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,TF,OPCML,PTPN5,P2RX7,PAH,DAAM2,PAX6,TNFRSF1B,CDC42,PADI2,PCDH8,DCLK1,HRH3,MAGI1,PDE4B,PDYN,CHGA,CHRM1,CHRM4,CHRNB2,DLGAP3,NRXN1,NRXN2,PIK3CD,FADS2,FTO,SULT4A1,PLXNB3,PMP2,SLC25A27,BEST1,CP,POU3F2,ETNPPL,CRMP1,TENM4,PPP3CB,FEZ1,NCAN,CALY,CTNND2,MAPK8,NOS1AP,PSD,KIAA0513,RIMS3,BDNF-AS,CNIH3,LRP8,MAGI2,PTPRZ1,KCNH1,SV2A,SRGAP3,KCNJ10,ARNT2,PCDH15,NAV2,KCNN3,KCNQ2,DLG2,DLG3,KIF2A,CALN1,DNM2,SLC17A6,RASGRF1,RTN4,NUP214,USH1C,RGS10,EEF1A2,EN2,OLIG2" Disease C0005586 Bipolar Disorder DisGeNET Curated 5.34E-12 3.39E-08 1.70E-08 1.58E-07 77 730 "MAPT,ADCY2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK3,NTNG1,NLGN1,SLC1A2,SLC1A6,MTR,ASTN1,SNAP25,ATP1A2,NRG3,ATP1A3,FYN,GAD2,CPLX2,NPAS3,NCAM1,LMO3,GFAP,FGF17,MLC1,ARHGEF7,ASTN2,CACNA1A,CACNB2,TCF7L2,NRGN,CAMK2A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PTPN5,P2RX7,TLL2,PAH,TNR,DCLK1,SEZ6L,MAGI1,PDE4B,PDYN,PFKFB3,NRXN1,FADS2,FTO,POU3F2,ETNPPL,PTPA,TENM4,PPP3CB,FEZ1,NCAN,PRKCZ,CTNND2,PSD,BDNF-AS,MAGI2,KCNN3,KCNQ2,DLG2,DLG3,SLC17A6,DSCAM,RASGRF1,RTN4,RFX4" Disease C0036572 Seizures DisGeNET Curated 1.34E-11 8.54E-08 2.85E-08 2.66E-07 93 982 "ABAT,MAPT,ACHE,ADGRV1,EYA1,ARID1A,ADAR,RYR1,AGT,SCN3A,PLA2G6,ASIC4,FOXG1,AMPH,ANK1,APBB1,SESN3,NTNG1,DGKD,SLITRK3,AQP4,SLC1A2,SLC6A9,SLC8A3,MT3,CCDC88A,ASCL1,MTR,SMARCE1,ALDH4A1,ATM,ATP1A2,GABBR1,SOX10,GAD2,NCAM1,LMO3,GFAP,MLC1,ARHGEF7,ABCC8,GNAS,GNG3,CNTN2,CACNA1A,GRIA1,GRIA2,GRIK2,GRIN1,GRM3,CRB1,PAH,TNFRSF1B,PC,TNS1,SEZ6L,LGI1,PDYN,ADGRG1,HMGB1,CHRM1,CHRNB2,NRXN1,PIK3CD,PMS2,NSD2,CRMP1,MAPK10,PROX1,ANKS1B,PTCH1,DNAJC6,PLPPR1,MAGI2,KCNA1,KCNA2,KCNC1,KCNH1,SV2A,SRGAP3,KCNJ10,KCNJ11,ARNT2,KCNK2,PEX5,KCNQ2,KIF2A,GNE,L1CAM,RET,EEF1A2,BSCL2,RPE65" Disease C3714756 Intellectual Disability DisGeNET Curated 2.44E-10 1.55E-06 3.87E-07 3.61E-06 99 1131 "EPS8,MAPT,APC2,LGR4,EYA1,ARID1A,CLIP1,WAC,NLGN4X,SCN3A,PLA2G6,FOXG1,CDC42BPA,ANK1,ANK3,APC,NTNG1,ST3GAL3,SHANK2,ASCL1,MTR,SMARCE1,ALDH4A1,SNAP25,ATP1A2,MYT1L,SOX5,SOX10,EMC1,NPAS3,KIRREL3,ABCC8,GNAS,DDHD2,CAMTA1,CNDP1,NUDT21,CAMK2A,GRIA2,GRIK2,GRIK4,GRIN1,OMG,CRB1,MFSD2A,AIFM1,PAH,PAX6,PC,CDC42,TNR,RBFOX2,ADGRG1,TUB,HNRNPK,HEPACAM,NLGN3,CADM1,NRXN1,BEST1,ATCAY,NXPH1,POU3F2,PTPA,RGS6,FMN2,PRKCG,CTNND2,MAPK10,MASP1,ZBTB16,GON4L,ZNF385B,PTCH1,DNAJC6,KCNA2,KCNH1,SRGAP3,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,RALGDS,DSCAM,L1CAM,NUP214,RET,USH1C,RGR,JMJD1C,RGS7,EEF1A2,RLBP1,SLC4A10,ROM1,BSCL2,RPE65" Disease C0004352 Autistic Disorder DisGeNET Curated 6.62E-10 4.20E-06 8.41E-07 7.85E-06 66 644 "EPS8,ABAT,MBP,CSMD3,CLIP1,WAC,NLGN4X,AGT,SCN3A,FOXG1,ANK3,APBA2,APC,NTNG1,NLGN1,AQP4,SLC1A2,SHANK2,MTR,SNAP25,ATP2B2,GABBR1,GAD2,NCAM1,NDUFA5,ASTN2,ROBO3,CACNA1A,CACNB2,GRIA1,GRIA2,GRIK2,GRIK4,TF,SPX,PAH,PAX6,TNFRSF1B,PCDH9,CDH8,CDH10,PDE4B,CHRNB2,HEPACAM,NLGN3,CADM1,NRXN1,PIK3CD,CP,PLD5,CTNND2,MAPK8,PSD,RIMS3,ITGAV,CADM2,LRP8,CSDE1,STMN4,PTPRZ1,KCNMA1,DLG3,DSCAM,RASGRF1,JMJD1C,EN2" Disease C0233514 Abnormal behavior DisGeNET Curated 1.44E-09 9.16E-06 1.53E-06 1.43E-05 45 365 "MAP6,MAPT,TUBB4A,SEMA6A,ANK3,SHANK2,SNAP25,ATM,SOX5,GAD2,NPAS3,NCAM1,LMO3,GJB1,ARHGEF7,SYT4,CAMTA1,GPM6A,HAP1,GRIA1,GRIK2,GRIN1,GRM3,PAH,DCLK1,MAGI1,PDE4B,PDYN,CHRM4,NLGN3,DLGAP3,NRXN1,SULT4A1,FEZ1,CTNND2,NOS1AP,PSD,PSMD13,PLPPR4,PEX5,DLG3,ATN1,L1CAM,SLC6A15,OLIG2" Disease C0014544 Epilepsy DisGeNET Curated 7.36E-09 4.68E-05 6.68E-06 6.23E-05 84 962 "ABAT,MAPT,ADGRV1,ARID1A,MDM4,FABP7,SCN3A,PLA2G6,SEMA6A,FOXG1,ANK2,APBA2,SESN3,NTNG1,AQP4,SLC1A2,SLC6A9,CCDC88A,ASCL1,MTR,SMARCE1,ALDH4A1,ATM,ATP1A2,ATP1A3,GABBR1,SOX10,GFAP,MLC1,ABCC8,GNAS,CAMSAP2,CNTN2,CACNA1A,GRIA1,GRIA2,GRIK2,GRIN1,GRM3,CRB1,PTPN5,PAH,PAX6,PC,RBFOX2,LGI1,PDYN,ADGRG1,HMGB1,CHRM1,CHRNB2,NRXN1,PIK3CD,FTO,BEST1,PMS2,NSD2,PTPA,PTCH1,DNAJC6,MAGI2,KCNA1,KCNA2,KCNC1,KCNH1,SV2A,KCNJ10,KCNJ11,ARNT2,KCNK2,KCNMA1,PEX5,KCNQ2,KIF2A,SLC17A6,GOPC,GNE,L1CAM,RET,EEF1A2,SLC4A10,BSCL2,RPE65,SEZ6" Disease C0004936 Mental disorders DisGeNET Curated 2.74E-08 1.74E-04 2.17E-05 2.03E-04 39 321 "MAG,SLITRK1,ADCYAP1R1,TUBB4A,SEMA6A,ANK3,SNAP25,NPAS3,NCAM1,LMO3,GFAP,ARHGEF7,SYT4,ACSL6,CACNB2,NRGN,GRIA1,GRIK4,GRIN1,PAH,KCNK10,DCLK1,MAGI1,PDE4B,PDYN,CHRM4,NRXN1,FTO,SULT4A1,ATCAY,FEZ1,CTNND2,NOS1AP,PSD,PSMD13,BDNF-AS,PLPPR4,SLC6A15,OLIG2" Disease C0025362 Mental Retardation DisGeNET Curated 8.14E-08 5.17E-04 5.75E-05 5.36E-04 76 885 "MAPT,APC2,LGR4,EYA1,ARID1A,NLGN4X,SCN3A,PLA2G6,FOXG1,CDC42BPA,ANK1,ANK3,APC,NTNG1,SHANK2,ASCL1,MTR,SMARCE1,ALDH4A1,SNAP25,ATP1A2,MYT1L,SOX5,SOX10,NPAS3,ABCC8,GNAS,DDHD2,GRIK2,GRIK4,GRIN1,OMG,CRB1,AIFM1,PAH,PAX6,PC,CDC42,RBFOX2,ADGRG1,TUB,HNRNPK,HEPACAM,NLGN3,CADM1,NRXN1,BEST1,ATCAY,NXPH1,RGS6,CTNND2,MAPK10,MASP1,ZBTB16,ZNF385B,PTCH1,DNAJC6,SRGAP3,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,DSCAM,L1CAM,NUP214,RET,USH1C,RGR,EEF1A2,RLBP1,SLC4A10,ROM1,BSCL2,RPE65" Disease C0001973 "Alcoholic Intoxication, Chronic" DisGeNET Curated 2.15E-07 1.36E-03 1.36E-04 1.27E-03 43 402 "ABAT,MBP,DSCAML1,NLGN4X,TESK2,AGT,SEMA6A,MOBP,MOG,SGIP1,SLC1A2,PKNOX2,SLC6A9,TAGLN3,ASTN1,FYN,GABBR1,GAD2,NCAM1,LMO3,GFAP,ARHGEF7,LILRA1,NRDC,CAMK2A,GRIK3,GRIN1,GRM3,TF,CCKBR,CDH8,CDH10,PDE4B,PDYN,HMGB1,PIK3CD,FTO,CNIH3,LRP8,KCNN3,NKAIN1,ATN1,RFX4" Disease C0011570 Mental Depression DisGeNET Curated 3.21E-07 2.04E-03 1.80E-04 1.68E-03 53 554 "EYA1,CSMD2,NDRG2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK1,FOLH1,STK32C,AQP4,SLC1A2,MT3,MTR,SNAP25,ATM,ATP1A3,CPLX2,NCAM1,LMO3,GFAP,FGF17,NELL1,SLCO1C1,WWC1,GPM6A,GPR26,CAMK2A,GRIA1,GRID1,GRIK3,GRIN1,GRM3,TGFBR3,P2RX7,TNFRSF1B,LGI1,PDE4B,PDYN,PFKFB3,CHRNB2,NRXN1,FTO,NXPH1,MAPK8,NOS1AP,SIRPA,BDNF-AS,KCNK2,ATN1,ABCC9,SLC6A15,SLC4A10" Disease C0027765 nervous system disorder DisGeNET Curated 3.41E-07 2.17E-03 1.80E-04 1.68E-03 44 423 "MAPT,ACHE,FABP7,TUBB4A,PLA2G6,ASIC4,FOXG1,MOG,AQP4,SLC1A2,SHANK2,ASCL1,ARFGAP1,MTR,SNAP25,ATM,ATP1A2,ATP1A3,SOX10,CPLX2,GFAP,NEUROD1,VAMP1,CACNA1A,GRIA2,INA,LGI1,PDYN,HMGB1,FTO,COL9A2,ATCAY,CP,PNKD,HES5,PTHLH,SV2A,KCNQ2,DLG3,DNM2,L1CAM,RET,ATL1,EEF1A2" Disease C0002395 Alzheimer's Disease DisGeNET Curated 4.57E-07 2.90E-03 2.23E-04 2.08E-03 128 1825 "SERPINA3,MAPT,ACHE,APC2,MBP,RTN3,IL17D,ECSIT,NDRG2,ADCY2,ADD3,SORCS1,AGT,FGF1,PLA2G6,SEMA6A,SLC30A10,MOG,FOXM1,AMPH,SFPQ,ANK1,FOLH1,PKP4,SH3GL2,APBA2,APBB1,APC,BCAN,SYBU,NLGN1,ST8SIA1,AQP4,SLC1A2,MADD,MSRA,SLC8A3,MT3,SHANK2,PDE8B,SCG3,MTR,SORCS3,SNAP25,ATM,SNCB,NRG3,FYN,WDTC1,NMNAT2,CPLX2,FXYD6,LMO3,NDUFA5,GFAP,GFRA1,RND1,NFIA,ARHGEF7,VAMP1,PCDH11X,ASTN2,WWC1,DDR1,NPPA,NRDC,NRGN,HAP1,AZIN2,PTBP2,CAMK2A,BRSK2,GRIA1,GRIA2,GRIK4,GRIN1,TF,OLR1,PTPN5,P2RX7,ATG4C,PAX6,TNFRSF1B,PC,CDC42,HRH3,PDYN,NTSR2,PFKFB3,CHRM1,CHRNB2,TMEFF2,JAM2,HPCA,SERPINE2,PIK3CD,FTO,SLC25A27,BEST1,PRRX1,ATCAY,CP,POU3F4,CRMP1,PTPA,SNCAIP,VCAN,PRKACB,CTNND2,MAPK8,MAPK10,ECE2,MASP1,KLK6,PSD,ANKS1B,LRRTM3,PTCH1,SV2A,KCNMA1,DLG3,DNM2,ATN1,ABCC9,NUP214,RET,EEF1A2,ELAVL4" Disease C0004114 Astrocytoma DisGeNET Curated 6.20E-07 3.93E-03 2.81E-04 2.62E-03 63 721 "ACHE,MBP,WLS,MDM4,NDRG2,F3,FABP7,CHST15,SEMA6A,FOLH1,APC,AQP4,SLC1A2,ASCL1,DLL3,B3GAT1,ATM,DKK3,WDTC1,SOX10,NPAS3,NCAM1,ALDH1L1,GPR162,GFAP,MLC1,ARHGEF7,NKX2-2,CAMTA1,BTRC,CNTN2,TCF7L2,DIRAS1,AZIN2,PSD3,P2RX7,AIFM1,NEURL1,PAX6,CDC42,LGI1,TPM3,PDE3B,PFKFB3,SERPINE2,PIK3CD,FTO,VAV2,RGS6,CSF3R,VCAN,MAPK8,HES5,KLK6,SIRPA,PTHLH,PTPRZ1,PID1,DNM2,ATN1,RASGRF1,BSCL2,OLIG2" Disease C1510586 Autism Spectrum Disorders DisGeNET Curated 7.87E-07 5.00E-03 3.33E-04 3.11E-03 44 436 "FABP7,NLGN4X,FOXG1,MOG,ANK3,APBA2,APC,NLGN1,SHANK2,SNAP25,ATP2B2,SOX5,GFAP,KIRREL3,ASTN2,CACNA1A,CACNB2,GRIK4,PAH,PAX6,PCDH9,CDH8,SEZ6L,NLGN3,CADM1,NRXN1,NRXN2,PIK3CD,NXPH1,POU3F2,CTNND2,MAPK10,PSD,LRRTM3,BDNF-AS,KCNJ10,ARNT2,PCDH15,DPP6,L1CAM,JMJD1C,CBLN2,ROM1,EN2" Disease C0011581 Depressive disorder DisGeNET Curated 1.89E-06 1.20E-02 7.49E-04 6.99E-03 60 697 "MAPT,EYA1,CSMD2,NDRG2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK1,FOLH1,STK32C,AQP4,SLC1A2,MT3,MTR,SNAP25,ATM,ATP1A3,CPLX2,NCAM1,LMO3,GFAP,FGF17,NELL1,SLCO1C1,GNAS,WWC1,GPM6A,GPR26,CAMK2A,GRIA1,GRID1,GRIK3,GRIN1,GRM3,TGFBR3,P2RX7,PAH,TNFRSF1B,LGI1,PDE4B,PDYN,CHRNB2,CADM1,NRXN1,FTO,PMS2,NXPH1,CP,SNCAIP,PRKCG,MAPK8,NOS1AP,SIRPA,BDNF-AS,KCNK2,ATN1,ABCC9,SLC6A15,SLC4A10" Disease C0728829 Congenital pes cavus DisGeNET Curated 2.50E-06 1.59E-02 9.33E-04 8.71E-03 16 89 "ATP1A3,SOX10,MYH7,KIF1B,SPART,GJB1,VAMP1,AIFM1,TPM3,DNAJC6,PEX5,DNM2,L1CAM,RET,ATL1,BSCL2" Disease C0027819 Neuroblastoma DisGeNET Curated 2.89E-06 1.84E-02 1.02E-03 9.53E-03 117 1689 "MAPT,ACHE,EXTL1,CEND1,MEG3,ATAT1,ARID1A,WLS,MDM4,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,FABP7,PLA2G6,SEMA6A,FOXM1,SFPQ,ANK2,ITSN1,APC,URGCP,SLC2A5,MADD,NBPF1,MSRA,ASCL1,SCG3,ASPH,B3GAT1,SNAP25,ATM,SNCB,DKK3,WDTC1,B4GALNT1,KIF1B,GART,DNER,NCAM1,LMO3,MIR100HG,BCL2L2,SMOC1,GFAP,NEUROD1,AJAP1,NFIA,ARHGEF7,NHLH1,NKX2-2,GNAS,CAMTA1,UNC5D,BTRC,WWC1,PRUNE2,NPPA,NEU4,NRDC,NRGN,PTBP2,CAMK2G,GRIA2,PTPN5,TGFBR3,P2RX7,CD81,CDK11B,TNFRSF1B,CDC42,DCLK1,LGI1,TPM3,PDYN,HMGB1,CHGA,DUSP26,SERPINE2,CADM1,NEGR1,PIK3CD,HPR,FTO,SLC25A27,PMS2,CRMP1,PTPA,SNCAIP,CSF3R,CHD5,RBPJ,PRKCZ,SLC45A1,MAPK8,HES5,PROX1,ACY3,PTCH1,ITGAV,PTHLH,PRDM2,LRP8,STMN4,PTPRD,SRGAP3,ARNT2,NAV2,ATN1,RASGRF1,PAK5,L1CAM,NUP214,RET,VANGL2,LMO1,ELAVL4" Disease C0700095 Central neuroblastoma DisGeNET BeFree 4.38E-06 2.78E-02 1.46E-03 1.37E-02 113 1631 "MAPT,ACHE,EXTL1,CEND1,MEG3,ATAT1,ARID1A,WLS,MDM4,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,FABP7,PLA2G6,SEMA6A,FOXM1,SFPQ,ANK2,ITSN1,APC,URGCP,MADD,NBPF1,MSRA,ASCL1,SCG3,ASPH,B3GAT1,SNAP25,ATM,SNCB,DKK3,WDTC1,B4GALNT1,KIF1B,GART,DNER,NCAM1,LMO3,MIR100HG,BCL2L2,SMOC1,GFAP,NEUROD1,AJAP1,NFIA,ARHGEF7,NHLH1,NKX2-2,GNAS,CAMTA1,UNC5D,BTRC,WWC1,PRUNE2,NPPA,NEU4,NRDC,NRGN,PTBP2,CAMK2G,GRIA2,PTPN5,TGFBR3,P2RX7,CD81,CDK11B,TNFRSF1B,CDC42,DCLK1,LGI1,TPM3,PDYN,HMGB1,CHGA,DUSP26,SERPINE2,CADM1,NEGR1,PIK3CD,HPR,FTO,SLC25A27,CRMP1,PTPA,SNCAIP,CSF3R,CHD5,SLC45A1,MAPK8,HES5,PROX1,ACY3,PTCH1,ITGAV,PTHLH,PRDM2,LRP8,STMN4,PTPRD,SRGAP3,ARNT2,NAV2,ATN1,RASGRF1,PAK5,L1CAM,NUP214,RET,VANGL2,LMO1,ELAVL4" Domain PF00047 ig Pfam 4.86E-08 1.60E-04 5.12E-05 4.44E-04 26 190 "FGFRL1,FCRL3,PDGFRA,PIGR,FCRL5,FCRL2,F11R,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,FGFR3,FLT1,FLT3,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT" Domain IPR013151 Immunoglobulin InterPro 4.86E-08 1.60E-04 5.12E-05 4.44E-04 26 190 "FGFRL1,FCRL3,PDGFRA,PIGR,FCRL5,FCRL2,F11R,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,FGFR3,FLT1,FLT3,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT" Domain SM00409 IG SMART 6.25E-08 2.05E-04 5.12E-05 4.44E-04 42 421 "SLAMF6,MYBPC1,CADM3,FGFRL1,CD84,FCRL3,MPZL1,FCRLB,PDGFRA,PIGR,NCR1,VCAN,FCRL5,FCRL2,F11R,KIRREL1,FCAMR,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,LRRN2,FGFR3,FLT1,FLT3,CD244,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,FCRLA,IGSF8,FCRL6,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT,SLAMF9" Domain IPR003599 Ig_sub InterPro 6.25E-08 2.05E-04 5.12E-05 4.44E-04 42 421 "SLAMF6,MYBPC1,CADM3,FGFRL1,CD84,FCRL3,MPZL1,FCRLB,PDGFRA,PIGR,NCR1,VCAN,FCRL5,FCRL2,F11R,KIRREL1,FCAMR,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,LRRN2,FGFR3,FLT1,FLT3,CD244,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,FCRLA,IGSF8,FCRL6,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT,SLAMF9" Domain PS50835 IG_LIKE PROSITE 6.70E-07 2.20E-03 4.40E-04 3.82E-03 44 492 "SLAMF6,MYBPC1,CADM3,FGFRL1,CD84,FCRL3,MPZL1,CD1D,CD1E,FCRLB,PDGFRA,PIGR,NCR1,VCAN,FCRL5,FCRL2,F11R,KIRREL1,FCAMR,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,LRRN2,FGFR3,FLT1,FLT3,CD244,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,FCRLA,IGSF8,FCRL6,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT,SLAMF9" Domain IPR007110 Ig-like_dom InterPro 1.28E-06 4.21E-03 7.02E-04 6.09E-03 44 504 "SLAMF6,MYBPC1,CADM3,FGFRL1,CD84,FCRL3,MPZL1,CD1D,CD1E,FCRLB,PDGFRA,PIGR,NCR1,VCAN,FCRL5,FCRL2,F11R,KIRREL1,FCAMR,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,LRRN2,FGFR3,FLT1,FLT3,CD244,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,FCRLA,IGSF8,FCRL6,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT,SLAMF9" Domain 2.60.40.10 - Gene3D 3.51E-06 1.15E-02 1.64E-03 1.43E-02 52 663 "SLAMF6,ASTN1,MYBPC1,CADM3,FGFRL1,CD84,FCRL3,NFATC4,MPZL1,CD1D,CD1E,FCRLB,PDGFRA,PIGR,NCR1,VCAN,FCRL5,FCRL2,PTPRC,F11R,KIRREL1,FCAMR,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,LRRN2,FGFR3,FLT1,FLT3,CD244,NFASC,LILRB1,CNTN2,ADGRA3,LILRB4,FCRLA,TGM1,RIMBP2,TNR,IGSF8,PAPPA2,FCRL6,IL6ST,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT,SLAMF9" Pubmed 15057823 The DNA sequence and analysis of human chromosome 13. Pubmed 1.33E-55 8.41E-51 8.41E-51 9.79E-50 60 170 "CUL4A,ATP4B,STARD13,ATP7B,DAOA,CHAMP1,PCDH9,ZMYM5,RCBTB2,GPR180,TM9SF2,MPHOSPH8,COG3,DCT,TBC1D4,SACS,RNF219,B3GLCT,RB1,POLR1D,CRYL1,SETDB2,MBNL2,DCUN1D2,BORA,SAP18,F7,FGF9,PIBF1,FOXO1,SUPT20H,RUBCNL,UFM1,CENPJ,ATP8A2,HSPH1,OXGR1,PCDH17,COMMD6,GJA3,GJB2,ATP11A,GPR12,GPR18,DOCK9,XPO4,KLF12,TUBA3C,HTR2A,TPTE2,ZMYM2,ZAR1L,CAB39L,DIAPH3,SPRYD7,ZDHHC20,LIG4,SKA3,MICU2,SPATA13" Pubmed 20178780 The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Pubmed 9.99E-30 6.31E-25 3.16E-25 3.67E-24 24 41 "DDX55,RILPL1,RFLNA,ZNF664,NCOR2,C12orf65,OGFOD2,SBNO1,EIF2B1,MPHOSPH9,TCTN2,CLIP1,ARL6IP4,ZCCHC8,CCDC92,TMED2,KMT5A,SNRNP35,GTF2H3,ATP6V0A2,HSP90B1,RILPL2,DNAH10,CDK2AP1" Pubmed 19536175 Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. Pubmed 1.03E-24 6.51E-20 2.17E-20 2.52E-19 26 74 "ADORA1,RGS5,PPFIA4,BLZF1,CCDC181,ATP2B4,MPZL1,CHIT1,PIK3C2B,MPC2,POU2F1,RGS4,KLHL12,SELP,HSD17B7,PLEKHA6,TADA1,C1orf112,ADCY10,KDM5B,TMEM183A,GPR161,MAEL,CCDC190,NPHS2,AXDND1" Pubmed 26638075 A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Pubmed 2.98E-19 1.88E-14 4.70E-15 5.47E-14 104 1820 "RALGAPA1,BIRC6,ADD1,SEMA6A,APC,MSH2,BLZF1,ATP1A2,ATP2B4,KCTD12,BTF3,SLC5A6,CAD,GAS2L3,MPZL1,FCHO2,CCNB1,SCARB1,DCLK1,GPR180,TM9SF2,NOC4L,EPN1,HECTD1,TAPT1,COPA,LYSMD3,BRI3BP,TTC37,ITSN2,CEP135,IFT172,MATR3,SNX17,SPATA18,PSME1,SREK1,COG3,CEP350,CEP120,OCIAD1,F11R,PPP2R3C,RNF219,ARGLU1,IPO4,TMEM33,LATS2,KIRREL1,MPHOSPH9,MARVELD2,TCTN2,TBC1D19,CLIP1,GORAB,RELL1,PIBF1,VEZT,NBEA,CCDC92,SLC30A6,SCYL2,SLC12A2,N4BP2,WDCP,EFR3B,PUS1,UGGT2,LIMCH1,PDS5B,RAPGEF6,CENPJ,HSPH1,SRP72,NEDD1,ANKLE2,ERBIN,IKBIP,COMMD6,TMED2,SCFD1,GOLGA3,EML4,MSH6,AP4S1,TMPO,ATP6V0A2,KLF12,HSP90B1,HMGCR,POC5,HSD17B4,VRK2,YTHDC2,CENPH,SELENOI,TDRD3,CHPT1,KIF2A,DIAPH3,RPGRIP1,ZDHHC20,IFT88,SKA3" Pubmed 16710414 The DNA sequence and biological annotation of human chromosome 1. Pubmed 9.09E-14 5.74E-09 1.01E-09 1.17E-08 64 1031 "ABL2,MDM4,SLAMF6,ATP6V1G3,RGS5,BLZF1,ASTN1,B4GALT3,CADM3,PPP1R12B,CD84,MPZL1,CD1D,UHMK1,CDK18,RGSL1,PFKFB2,TSTD1,PIK3C2B,MPC2,FAM163A,POU2F1,DNM3,KIAA0040,FCRL5,NOS1AP,FCRL2,DDX59,PTGS2,DHX9,CEP350,F11R,FAM129A,METTL11B,RGS4,LGR6,FCGR2B,TOMM40L,GORAB,LRRN2,FMO1,MRPS14,KIF21B,PDS5B,NMNAT2,NFASC,KLHL20,ZBTB37,CNTN2,FCRLA,CRB1,GPR161,MAEL,TNR,NPL,ARHGAP30,PAPPA2,FCRL6,CCDC190,ZBTB41,LINC00272,LHX9,KCNJ9,SLAMF9" Pubmed 25921289 Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Pubmed 9.55E-14 6.03E-09 1.01E-09 1.17E-08 95 1922 "ABL2,MAP1B,ADD1,KIAA1211,WDR35,MSH2,DDX55,ATP12A,ARHGEF7,CAD,PCK2,XPR1,PDGFRA,CHD1,SLC25A3,PIK3C2B,EPN1,STRN3,COPA,POLE,TTC37,EIF2AK2,MATR3,PSMA6,SREK1,PSME2,COG3,DHX9,TBC1D4,G3BP2,WDR1,RAN,RNF31,RASA1,RB1,ARGLU1,SMC6,IPO4,LAP3,TMEM33,LRPPRC,SBNO1,TRAPPC12,TRIM28,EIF2B1,TACC3,PIBF1,SFSWAP,ZCCHC8,PLEKHA6,PAICS,SCYL2,THADA,ARHGEF40,CCDC88A,SLC12A2,ACIN1,LIMCH1,CPSF3,PDS5B,GAK,HSPH1,MRPS27,KDM3B,SRP54,SRP72,MCCC2,ANKLE2,LRCH1,LPIN1,STRN,PSME4,SCFD1,PPIP5K2,METAP2,GOLGA3,EML4,XPO4,NCSTN,TGM1,MSH6,GTF3C2,TMPO,HSP90B1,UBC,HSD17B4,WDR36,YTHDC2,PGAM5,FIP1L1,KIF2A,LETM1,LMNB1,PABPN1,LTA4H" Pubmed 10737774 Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis. Pubmed 4.33E-13 2.74E-08 3.91E-09 4.54E-08 8 9 "MYH6,NEDD8,PCK2,CMA1,LTB4R,CTSG,RABGGTA,GZMH" Pubmed 24457600 The central role of EED in the orchestration of polycomb group complexes. Pubmed 5.34E-12 3.37E-07 4.22E-08 4.90E-07 84 1719 "MAP1B,BIRC6,CUL4A,EP400,FBRSL1,MSH2,ARL1,NOP14,GAS2L3,NFXL1,SLC25A3,CPNE6,PIGR,SNX6,PKP1,NOC4L,EPN1,COPA,RCHY1,NGDN,BRI3BP,ITSN2,MPHOSPH8,MATR3,PSMA6,DMXL1,DHX9,NOP9,G3BP2,WDR1,TSEN15,DNMT3A,RAN,ARGLU1,IPO4,LAP3,TMEM33,LRPPRC,MBNL2,TRIM28,KLHL12,SAP18,ETF1,PCGF3,CLIP1,UTP15,ZCCHC8,FBXO11,DDX51,NUBPL,PAICS,THADA,SF3B6,ACIN1,LIMCH1,SNRPF,CPSF3,PDS5B,GAK,HSPH1,SRP54,SRP72,LRCH1,UTP20,SCFD1,METAP2,XPO4,TGM1,MSH6,BAZ1A,GZMH,TMPO,HSP90B1,UBE2K,HSD17B4,TENT2,WDR36,NSD2,ZMYM2,PGAM5,FIP1L1,LAD1,LMNB1,PABPN1" Pubmed 28671696 Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Pubmed 6.20E-12 3.92E-07 4.36E-08 5.07E-07 56 916 "MCC,TMEM132B,ADD1,APC,SLC4A4,ATP2B4,KCTD12,ARHGEF7,CACNA1E,CAD,LDB2,DCLK1,NRXN1,JAKMIP1,HOMER1,STRN3,PREPL,NCOR2,DNM3,PRKD1,MATR3,G3BP2,WDR1,RAN,ARGLU1,IPO4,LRPPRC,TRIM28,ZNF219,ETF1,CLIP1,TACC3,FOXG1,NBEA,CCDC88A,N4BP2,LIMCH1,KIF21B,CENPJ,UHRF1BP1L,IQGAP2,NFASC,ERBIN,STRN,GOLGA3,RIMBP2,TNR,TRPC4,ANKS1B,ZMYM2,PGAM5,TDRD3,KIF2A,LETM1,LMNB1,SPATA13" Pubmed 27626380 High-throughput discovery of novel developmental phenotypes. Pubmed 1.58E-11 9.97E-07 9.97E-08 1.16E-06 80 1633 "RGS5,CCDC181,CD84,NFATC4,ADGRD1,CBLN3,CDKL2,MPZL1,CAST,RILPL1,CCNB1,SCARB1,PCSK1,CHD1,PFKFB2,SLC25A3,NRXN1,ATAD2B,HECTD1,ANAPC4,STRN3,FAM163A,SYCP3,EPGN,ITSN2,DGKQ,EPS8L1,COG3,DCT,KLHL3,TBC1D4,GNPDA2,DHFR,RABGGTA,DNMT3A,REST,MEMO1,NTN4,EFNA5,GRTP1,MARVELD2,DRAM1,ARSK,CWC27,MAEA,ADGRV1,F7,F10,FGF9,PIBF1,VEZT,SH3BP2,NUBPL,THADA,PKD2L2,C1orf112,CPSF3,IQGAP2,GC,GOLGA3,ADGRL3,RIPK3,ARHGEF28,FCRLA,TEP1,BAZ1A,RXFP2,DCP2,CENPH,IL6ST,SPTSSA,GALP,PGAM5,FAM151B,KCNJ9,CAB39L,DIAPH3,RILPL2,IFT88,LTA4H" Pubmed 17273841 The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL. Pubmed 2.25E-11 1.42E-06 1.29E-07 1.50E-06 8 12 "FCRL3,FCRLB,FCRL5,FCRL2,FCGR3A,FCGR3B,FCRLA,FCRL6" Pubmed 19322201 Ubiquitin-mediated proteolysis of HuR by heat shock. Pubmed 4.80E-11 3.04E-06 2.45E-07 2.84E-06 80 1671 "APAF1,ATP7B,BCL2L2,GAS2L3,MPZL1,CAST,UHMK1,ZNF664,PCDH9,XPR1,CHD1,GPR180,SMIM14,SNX6,CFAP45,STRN3,PREPL,CSNK1G3,EIF2AK2,BIVM,SREK1,KLHL3,F11R,G3BP2,SLC35F6,RNF219,RAN,B3GLCT,ARGLU1,DTD2,CRYL1,LATS2,MBNL2,MARVELD2,TCTN2,STX2,FAM172A,IRF9,VEZT,FBXO11,CCDC92,UFM1,SLC22A5,YPEL5,ACIN1,LIMCH1,SNRPF,KDM5B,EAPP,MRPS27,KDM3B,IKBIP,STRN,TMED2,GOLGA3,EML4,KMT5A,RNF212,COP1,XPO4,NCSTN,TFDP1,BAZ1A,RAB2B,ATP6V0A2,UBC,TENT2,DCP2,CENPH,SELENOI,SPTSSA,ZMYM2,ZBTB41,LINC00272,CHPT1,NUAK2,LMNB1,CDK2AP1,PABPN1,LTA4H" Pubmed 28611215 Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Pubmed 5.03E-11 3.18E-06 2.45E-07 2.84E-06 74 1489 "RALGAPA1,MAP1B,MDM4,TBC1D14,SEMA6A,CUL4A,PITPNM2,UVSSA,FBRSL1,APBB2,FGFRL1,ADGRD1,CAST,SYT2,RILPL1,SCARB1,SNTG2,PCCA,PDE4D,ZNF595,BOD1L1,HECTD1,FAM53A,NCOR2,BRI3BP,PRKD1,DCAF8,COG3,TBC1D4,TSEN15,RASA1,LRPPRC,EFNA5,LATS2,GRTP1,RNF4,MBNL2,ELK3,TBC1D19,MAEA,ADGRV1,PCGF3,F7,SH3YL1,FNIP1,TNFRSF19,POLK,RASA3,VEZT,SH3BP2,G2E3,THADA,LIMCH1,NMNAT2,SRP54,NFASC,MCCC2,NEDD1,ERBIN,ZNF544,TBC1D1,ATP11A,TEP1,UBE2K,HPCAL1,NSD2,IGF1,ZFHX2,ZNF84,SPTSSA,LMLN,KCNN2,CAB39L,EP400P1" Pubmed 11345588 Nucleotide sequence analysis of the approximately 35-kb segment containing interferon-gamma-inducible mouse proteasome activator genes. Pubmed 1.07E-10 6.78E-06 4.84E-07 5.63E-06 6 6 "FITM1,PSME1,PSME2,RNF31,EMC9,IRF9" Pubmed 14621295 Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 2.27E-10 1.44E-05 9.57E-07 1.11E-05 37 508 "RALGAPA1,HOMEZ,PITPNM2,EP400,UVSSA,FBRSL1,DDX55,WDR19,ATP1A2,ARHGEF7,CHAMP1,AKAP6,CLOCK,PREPL,TTC37,MATR3,SNX17,ADGRV1,G2E3,IVNS1ABP,CCDC88A,EFR3B,KIF21B,NMNAT2,KDM3B,NFASC,ANKLE2,LRCH1,MAST4,PSME4,SCFD1,PPIP5K2,XPO4,NCSTN,GTF3C2,NSD2,NUAK2" Pubmed 11401431 "Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23." Pubmed 4.08E-10 2.58E-05 1.61E-06 1.87E-05 9 22 "ATP1A2,CD84,CFAP45,COPA,DCAF8,F11R,NCSTN,IGSF8,KCNJ9" Pubmed 8125298 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Pubmed 1.08E-09 6.84E-05 4.03E-06 4.68E-05 83 1883 "ABL2,MDM4,ACOX3,MIPEP,MSH2,BLZF1,WDR19,CCNB1IP1,ATP1A2,CCDC181,FGFRL1,BTF3,CCNA1,RAB29,LDB2,CD1D,PCCA,CHIT1,SLC25A3,CPNE6,TM9SF2,PIGR,CFAP45,HOMER1,CLOCK,CRHBP,CTSG,DCAF8,SNX17,BIVM,PSME2,COG3,TINF2,SLC35F6,WDR1,PPP2R3C,GALNT14,EGLN3,ATG10,RNF31,LAP3,CLIP4,EIF2D,TXNDC15,TRIM28,UGT2A3,KLHL12,DHRS2,TBC1D19,ZNF671,ZNF219,CWC27,PCGF3,FCGR3A,TACC3,SDC1,SUPT20H,VEZT,SH3BP2,FBXO11,G2E3,CCDC92,NLRP2,CPSF3,GABRB1,EAPP,ZNF274,ERAP1,SRP72,GC,LILRB1,GJB2,BRD8,SCFD1,SLC7A8,TGFBI,ACTR6,GUF1,UGT2B7,VRK2,YTHDC2,ZNF26,LCP1" Pubmed 24952961 A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Pubmed 1.64E-09 1.04E-04 5.75E-06 6.69E-05 81 1835 "SEMA6A,HOMEZ,APC,STXBP6,ASCL1,NCOA1,ASTN1,ATP1A2,MYBPC1,KCTD12,CADM3,FGFRL1,NFATC4,NFKBIA,CBLN3,NRL,CAMK4,LDB2,SCARB1,PAH,NFXL1,PDGFRA,ITGBL1,NRXN1,PITX1,HOMER1,PMCH,POU2F1,CLOCK,NCOR2,PTGS2,COCH,PTPRC,NR1I3,NR1H4,DNMT3A,RB1,REST,RGS4,NTN4,EFNA5,TRIM28,ELF1,ELK3,ADGRV1,FGFR3,FOXG1,FOXO1,FLT1,FLT3,FMO1,SLC12A2,NR5A2,GABRA2,MYT1L,GABRB1,NPAS3,NFASC,NPFFR2,PPARGC1A,ADAM17,CNTN2,SPIC,GSX2,NCSTN,TFDP1,GPR161,TGM1,FZD10,MAEL,HGFAC,TRPC4,PAPPA2,HTR2A,NSD2,IGF1,ZFHX2,IL6ST,IRF1,LHX9,KIT" Pubmed 27173435 An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Pubmed 2.93E-09 1.85E-04 9.76E-06 1.14E-04 64 1321 "MCC,WDR35,CUL4A,MSH2,WDR19,STARD13,PCDH9,DCLK1,PCK2,CDK17,CDK18,PFKFB2,CCDC122,TM9SF2,NRXN1,MPC2,CLOCK,PRKD1,IFT172,DHX9,TBC1D4,CEP120,OCIAD1,RABGAP1L,SLC35F6,PXMP2,RB1,SMC6,IPO4,LRPPRC,SBNO1,EIF2B1,TCTN2,MAEA,PCGF3,CLIP1,PIBF1,UFM1,SCYL2,IVNS1ABP,THADA,CCDC88A,WDCP,SF3B6,YPEL5,UGGT2,DCAF11,UHRF1BP1L,IQGAP2,NEDD1,ANKLE2,IKBIP,STRN,TBC1D1,PPIP5K2,EML4,XPO4,GTF3C2,UBE2K,TUBA3C,CENPH,KIF3C,RPGRIP1,IFT88" Pubmed 28378742 Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Pubmed 3.54E-09 2.24E-04 1.12E-05 1.30E-04 72 1577 "MAP1B,ADD1,MSH2,ARL1,ATP1A2,ATP12A,ATP2B4,MYBPC1,KCTD12,MYH6,PNP,CAD,PDGFRA,DHRS1,SLC25A3,PIGR,LTB4R,MPC2,COPA,BRI3BP,CTSG,EIF2AK2,DCAF8,MATR3,PSMA6,DHX9,NOP9,PTPRC,RAN,REST,IPO4,TMEM33,LRPPRC,TRIM28,KIRREL1,ETF1,ADGRV1,F10,FGF9,ZCCHC8,SGCG,PAICS,SCYL2,IVNS1ABP,THADA,ACIN1,SNRPF,CPSF3,IQGAP2,ERAP1,HSPH1,MRPS27,MCCC2,STRN,NCSTN,TGFBI,MSH6,BAZ1A,TMPO,MAEL,HAL,HSP90B1,HMGCR,VRK2,WDR36,JCHAIN,PGAM5,FAM49A,LAD1,LCP1,LMNB1,MICU2" Pubmed 26673895 A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Pubmed 4.91E-09 3.10E-04 1.42E-05 1.66E-04 54 1038 "ADD1,TBC1D14,PITPNM2,SNX24,FBRSL1,BLZF1,NFKBIA,AP1G2,FCHO2,CCNB1,CDK17,PIK3C2B,PITX1,EPN1,ANAPC4,STRN3,COPA,NOS1AP,DCAF8,SNX17,CEP350,OCIAD1,C14orf119,RNF219,EIF2B1,MPHOSPH9,BORA,ETF1,ARL6IP4,UTP15,FOXO1,ZCCHC8,SH3BP2,PLEKHA6,SCYL2,CCDC88A,WDCP,LIMCH1,RAPGEF6,KDM3B,SRP54,SRP72,NEDD1,LRCH1,ERBIN,KLHL20,LPIN1,METAP2,KHNYN,GPN1,HPCAL1,POC5,FIP1L1,DIAPH3" Pubmed 16807745 Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution. Pubmed 4.96E-09 3.13E-04 1.42E-05 1.66E-04 5 5 "ATP12A,CMA1,CTSG,GZMH,SDR39U1" Pubmed 19064610 Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. Pubmed 1.07E-08 6.76E-04 2.94E-05 3.42E-04 10 40 "BLZF1,MPZL1,MPC2,POU2F1,SELP,TADA1,C1orf112,ADCY10,GPR161,MAEL" Pubmed 11544199 Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Pubmed 1.15E-08 7.29E-04 3.04E-05 3.53E-04 50 947 "APC,ARHGAP5,GAS2L3,FCHO2,NFXL1,DCLK1,PGGT1B,BOD1L1,AKAP6,CSNK1G3,VCAN,KIAA0040,MATR3,PTPRC,PARPBP,SMC6,N4BP2L2,POLK,SUCO,FBXO11,G2E3,PAICS,ACIN1,MYT1L,RAPGEF6,TMEM183A,UHRF1BP1L,IQGAP2,HSPH1,SRP54,ANKLE2,ERBIN,IKBIP,PPARGC1A,BRD8,PSME4,ATP11A,DOCK9,COX18,NCSTN,GRSF1,AP4S1,BAZ1A,ATP6V0A2,KLF12,UBC,ZBTB41,SDR39U1,KIF2A,LETM1" Pubmed 11709546 "Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification." Pubmed 2.19E-08 1.38E-03 5.53E-05 6.43E-04 7 16 "ATP1A2,CD84,COPA,DCAF8,NCSTN,IGSF8,KCNJ9" Pubmed 20360068 Systematic analysis of human protein complexes identifies chromosome segregation proteins. Pubmed 2.42E-08 1.53E-03 5.88E-05 6.84E-04 56 1149 "MCC,CUL4A,SNX24,APC,PPP1R12B,CHAMP1,CCNB1,SCFD2,CDK17,PDE4D,CENPC,PIGR,NUP37,HOMER1,ANAPC4,STRN3,COPA,ITSN2,CEP135,DCAF8,MATR3,DHX9,CEP350,CEP120,PPP2R3C,TSEN15,RNF219,RAN,SMC6,TRIM28,BORA,FAM172A,CLIP1,NDUFAF7,TACC3,PIBF1,HSD17B7,WDCP,SF3B6,DCAF11,SNRPF,PDS5B,EAPP,UHRF1BP1L,NEDD1,IKBIP,STRN,BRD8,TMED2,TGM1,GTF3C2,TMPO,POC5,DCP2,ZMYM2,LMNB1" Pubmed 21832049 "Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein." Pubmed 2.85E-08 1.80E-03 6.67E-05 7.76E-04 79 1891 "MCC,MDM4,NLN,RGS5,MCFD2,DDX55,CCNB1IP1,BTF3,NOVA1,CDKL2,TAF1B,DCLK1,PCK2,ZMYM5,CDK7,CDK17,CDK18,PDE4D,FAM53A,GNPTAB,POU2F1,C12orf65,FITM1,NOS1AP,ZFYVE16,PSME1,PIGG,PSME2,RASA1,ARGLU1,IPO4,DTD2,LAP3,CLIP4,DCUN1D2,ELK3,DRAM1,EFS,PCBD2,FCGR3A,NDUFAF7,GORAB,PIBF1,SDC1,RASA3,ZCCHC8,SGCG,TMEM175,NLRP2,ARHGEF40,TNFSF13B,C1orf112,SF3B6,UGGT2,LIMCH1,PDS5B,NMNAT2,GAK,NAAA,TMEM183A,IKBIP,METAP2,SPIC,GPR12,SNRNP35,AP4S1,RAB2B,TNNT2,NPL,KLF12,NSD2,CCDC190,ANKS1B,FIP1L1,EP400P1,RNASE11,LAD1,NUAK2,SKA3" Pubmed 27880917 Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Pubmed 4.40E-08 2.78E-03 9.92E-05 1.15E-03 52 1048 "RALGAPA1,BIRC6,MSH2,ARHGAP5,NOP14,ATP2B4,PPP1R12B,CAD,MPZL1,FCHO2,CENPC,SNX6,NOC4L,COPA,NCOR2,CEP135,NOS1AP,ZFYVE16,SNX17,PSME1,CEP350,NUDT12,TBC1D4,PTPRC,OCIAD1,PTPRH,KIRREL1,MPHOSPH9,MARVELD2,FAM172A,RELL1,PIBF1,VEZT,NBEA,CCDC88A,SLC12A2,EFR3B,PUS1,CPSF3,ANKLE2,ERBIN,XPO4,MSH6,TMPO,HSP90B1,POC5,HSD17B4,VRK2,NSD2,TPTE2,TDRD3,LETM1" Pubmed 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 6.21E-08 3.93E-03 1.35E-04 1.57E-03 45 852 "MAP1B,MDM4,KIAA1211,EP400,NOP14,MYH7,NFATC4,NFKBIA,NOVA1,LDB2,NFXL1,PKP1,COPA,POLE,POU2F1,NCOR2,SNX17,NOP9,TBC1D4,DHFR,RNF219,RB1,RNASEL,TRAPPC13,IRF9,FOXG1,FOXO1,FBXO11,BRMS1L,ALLC,IQGAP2,NPAS3,IKBIP,ZBTB37,BRD8,UTP20,COP1,TFDP1,TGM1,GTF3C2,BAZ1A,ZMYM2,FIP1L1,KIT,LIG4" Pubmed 10051400 Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Pubmed 7.05E-08 4.46E-03 1.49E-04 1.73E-03 10 48 "ATP1A2,B4GALT3,MPC2,COPA,DCAF8,F11R,NR1I3,RGS4,IGSF8,KCNJ9" Pubmed 10920231 Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation. Pubmed 8.67E-08 5.48E-03 1.77E-04 2.06E-03 6 12 "ATP1A2,COPA,DCAF8,NCSTN,IGSF8,KCNJ9" Pubmed 17081983 "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Pubmed 9.08E-08 5.73E-03 1.79E-04 2.08E-03 67 1546 "ABL2,MAP1B,ADD1,ULK1,APAF1,APC,NOP14,NFATC4,ARHGEF7,CAD,CAST,CHAMP1,NFXL1,PDE4D,CENPC,CFL2,CHD1,PITX1,BOD1L1,EPN1,COPA,NCOR2,CEP135,MPHOSPH8,MATR3,DHX9,CEP350,NOP9,TBC1D4,G3BP2,DNMT3A,TRIM28,MARVELD2,ZNF219,CLIP1,SFSWAP,DDX51,N4BP2,PUS1,ACIN1,RAPGEF6,EAPP,HSPH1,KDM3B,ANKLE2,ERBIN,BRD8,ADAM17,GOLGA3,ADGRA3,EML4,KHNYN,XPO4,MSH6,GTF3C2,BAZ1A,TMPO,ATP6V0A2,TRPC4,UBC,NSD2,DCP2,YTHDC2,MZF1,IL6ST,FIP1L1,TTC7A" Pubmed 10656920 "Structure and mapping of the mouse matrilin-3 gene (Matn3), a member of a gene family containing a U12-type AT-AC intron." Pubmed 9.81E-08 6.20E-03 1.88E-04 2.19E-03 5 7 "MATN3,ODC1,SDC1,ADAM17,KIF3C" Pubmed 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 1.33E-07 8.43E-03 2.48E-04 2.88E-03 34 565 "NDRG2,ADD1,ARHGAP5,STXBP6,ATP2B4,BCL2L2,MPZL1,CAST,SCARB1,C1orf116,NGDN,ZFYVE16,EPS8L1,F11R,RAN,ARGLU1,MARVELD2,RELL1,PLEKHA6,NLRP2,PAICS,SCYL2,SLC12A2,LIMCH1,ERBIN,ADAM17,GOLGA3,DOCK9,TMPO,UBC,IL6ST,DIAPH3,LAD1,TTC7A" Pubmed 11991713 An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia. Pubmed 1.40E-07 8.86E-03 2.53E-04 2.94E-03 8 29 "PCCA,GPR180,BIVM,DCT,MBNL2,UGGT2,GPR18,DOCK9" Pubmed 20800603 Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. Pubmed 1.44E-07 9.10E-03 2.53E-04 2.94E-03 24 315 "ABL2,BIRC6,CUL4A,APC,PDGFRA,CHIT1,CPNE6,CMA1,CTSG,GALNT14,TLR6,FLT3,NLRP2,ACIN1,IQGAP2,GCKR,KHNYN,TEP1,MSH6,GZMH,GZMB,HEXB,TPO,TXK" Pubmed 23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Pubmed 1.75E-07 1.11E-02 3.00E-04 3.49E-03 25 342 "PIGR,LACC1,IL20,F11R,FCGR2B,FCGR3A,FCGR3B,NLRP2,THADA,SLC22A4,SLC22A5,NR5A2,KIF21B,CD244,ERAP1,LILRB4,ACSL6,C5orf56,GPR18,FCRLA,ARHGAP30,TXK,IL6ST,IRF1,KIR2DL1" Pubmed 11431695 "Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail." Pubmed 2.02E-07 1.28E-02 3.36E-04 3.91E-03 7 21 "ATP1A2,CD84,COPA,DCAF8,NCSTN,IGSF8,KCNJ9" Pubmed 18718052 [Differential expression levels of killer immunoglobin-like receptor genotype in patients with hematological malignancies between high-risk and standard-risk groups]. Pubmed 2.29E-07 1.45E-02 3.70E-04 4.31E-03 4 4 "KIR2DL1,KIR2DL4,KIR3DL1,KIR3DL2" Pubmed 15618518 Mouse brain organization revealed through direct genome-scale TF expression analysis. Pubmed 2.48E-07 1.57E-02 3.87E-04 4.50E-03 70 1689 "NDRG2,BIRC6,HOMEZ,ASCL1,NCOA1,NFATC4,BTF3,NFKBIA,NRL,CHAMP1,LDB2,ZMYM5,PIWIL1,ZNF595,WDFY2,PITX1,POU2F1,CLOCK,ZFYVE16,NR1I3,NR1H4,ZNF329,REST,RNF4,MBNL2,TRIM28,ELF1,ELK3,KLHL12,ZNF219,SAP18,PCGF3,PCBD2,IRF9,TACC3,FOXG1,FOXO1,FBXO11,ZNF446,NR5A2,ZNF667,ACIN1,MYT1L,ADCY10,PDS5B,KDM5B,ZNF274,NPAS3,KDM3B,ZBTB37,BRD8,INSM2,SPIC,COP1,GSX2,RNF17,TFDP1,ZBTB49,BAZ1A,MAEL,KLF12,NSD2,TPTE2,MZF1,ZFHX2,ZMYM2,IRF1,ZBTB41,LHX9,ZDHHC20" Pubmed 15730517 A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia. Pubmed 2.57E-07 1.62E-02 3.87E-04 4.50E-03 5 8 "KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2" Pubmed 8589683 Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion. Pubmed 2.57E-07 1.62E-02 3.87E-04 4.50E-03 5 8 "PDGFRA,GABRA2,GABRB1,GSX2,KIT" Pubmed 22922362 Transcription factor Foxp3 and its protein partners form a complex regulatory network. Pubmed 4.14E-07 2.61E-02 6.08E-04 7.07E-03 25 358 "ADD1,DHX37,NOP14,CAD,GAS2L3,CCNB1,NOC4L,FAM129A,ELF1,SAP18,UTP15,ZCCHC8,DDX51,PAICS,ACIN1,SRP72,MSH6,GTF3C2,BAZ1A,TENT2,WDR36,NSD2,TDRD3,LCP1,SKA3" Pubmed 15302935 Large-scale characterization of HeLa cell nuclear phosphoproteins. Pubmed 5.65E-07 3.57E-02 7.97E-04 9.27E-03 40 773 "ADD1,HOMEZ,EP400,CAST,CHAMP1,STRN3,COPA,POU2F1,NCOR2,MATR3,DHX9,TBC1D4,PTPRC,ARGLU1,REST,EIF2D,TRIM28,ELF1,ELK3,CLIP1,TACC3,SFSWAP,ZCCHC8,DDX51,ACIN1,LIMCH1,PDS5B,RAPGEF6,KDM3B,ERBIN,BRD8,UTP20,SCFD1,EML4,MSH6,GZMB,TMPO,YTHDC2,ZMYM2,FIP1L1" Pubmed 18186800 Distribution of KIR genes in the Czech population. Pubmed 5.68E-07 3.59E-02 7.97E-04 9.27E-03 5 9 "KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2" Pubmed 20059953 A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Pubmed 6.01E-07 3.80E-02 8.26E-04 9.61E-03 60 1398 "ANKRD34B,BLZF1,ASCL1,NEDD8,NFATC4,BTF3,CAMK4,TAF1B,CHAMP1,LDB2,CEBPE,PITX1,NCOR2,SNCAIP,MPHOSPH8,NUDT12,SUPT7L,NR1I3,NR1H4,DNMT3A,RB1,ZNF329,POLR1D,RNF4,TRIM28,ELF1,ZNF219,SAP18,PCGF3,IRF9,TACC3,FOXG1,FOXO1,ZCCHC8,ZNF446,IVNS1ABP,NR5A2,ZNF667,ZNF274,ZBTB37,PPARGC1A,BRD8,INSM2,SPIC,STON1,GSX2,TFDP1,GTF2H3,GTF3C2,TMPO,MAEL,TNNT2,KLF12,TRPC4,MZF1,ZMYM2,IRF1,ZBTB41,LHX9,TRPC7" Pubmed 24194600 "The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data." Pubmed 6.52E-07 4.12E-02 8.76E-04 1.02E-02 49 1050 "NFATC4,CBLN3,CDKL2,CAST,RILPL1,ODC1,CCNB1,SCARB1,SLC25A3,NRXN1,ANAPC4,STRN3,SYCP3,EPGN,ITSN2,EPS8L1,COG3,DCT,KLHL3,GNPDA2,DNMT3A,RASA1,REST,NTN4,ARSK,CWC27,ADGRV1,F7,F10,FGF9,PIBF1,VEZT,THADA,C1orf112,LRCH1,GOLGA3,RIPK3,RXFP2,FCRL6,IL6ST,GALP,FAM151B,KCNJ9,CAB39L,KIF3C,DIAPH3,RILPL2,IFT88,LTA4H" Pubmed 8828042 An integrated genetic map of the pearl locus of mouse chromosome 13. Pubmed 6.97E-07 4.41E-02 9.18E-04 1.07E-02 6 16 "MAP1B,VCAN,DHFR,RASA1,HEXB,HMGCR" Pubmed 24255178 Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Pubmed 7.34E-07 4.64E-02 9.47E-04 1.10E-02 28 446 "RALGAPA1,BIRC6,NYNRIN,APC,FAM193A,NFATC4,XPR1,CDK17,CDK18,PFKFB2,HECTD1,STRN3,TBC1D4,LATS2,KIRREL1,MPHOSPH9,CLIP1,PIBF1,ZCCHC8,RAPGEF6,CENPJ,UHRF1BP1L,LRCH1,STRN,TBC1D1,PGAM5,KIF2A,LETM1" Pubmed 25201988 Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Pubmed 9.82E-07 6.21E-02 1.16E-03 1.34E-02 12 94 "MDM4,PITPNM2,RILPL1,NRXN1,C12orf65,SBNO1,MPHOSPH9,LRRN2,TMED2,KMT5A,SNRNP35,RILPL2" Pubmed 29632206 Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Pubmed 1.08E-06 6.83E-02 1.16E-03 1.34E-02 8 37 "CUL4A,MYH6,NEDD8,CCNB1,RB1,LATS2,UFM1,TNNT2" Pubmed 8198617 Cloning and structure of the human corticotrophin releasing factor-binding protein gene (CRHBP) Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "PCSK1,CRHBP,DHFR,RASA1" Pubmed 16622424 New nomenclature for Fc receptor-like molecules. Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "FCRLB,FCRL5,FCRLA,FCRL6" Pubmed 20508037 "Copy number, linkage disequilibrium and disease association in the FCGR locus." Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "FCGR2C,FCGR2B,FCGR3A,FCGR3B" Pubmed 19309690 "Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B." Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "FCGR2C,FCGR2B,FCGR3A,FCGR3B" Pubmed 27893413 "KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer." Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1" Pubmed 9734812 The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3. Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "NOP14,FAM193A,RNF4,SH3BP2" Pubmed 17356879 Species-specific evolution of the FcR family in endothermic vertebrates. Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "FCRLB,FCRL5,FCRLA,FCRL6" Pubmed 20439936 SNPs of Fc-gamma receptor genes and chronic periodontitis. Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "FCGR2C,FCGR2B,FCGR3A,FCGR3B" Pubmed 9027485 Comparative linkage mapping of human chromosome 13 and bovine chromosome 12. Pubmed 1.10E-06 6.94E-02 1.16E-03 1.34E-02 4 5 "DCT,RB1,FLT1,HTR2A" Pubmed 24571439 Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment. Pubmed 1.12E-06 7.05E-02 1.16E-03 1.34E-02 5 10 "ADCY4,DHRS1,LTB4R,NOP9,CIDEB" Pubmed 23000965 Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Pubmed 1.21E-06 7.63E-02 1.23E-03 1.43E-02 15 151 "BIRC6,PFKFB2,NUP37,MATR3,PSMA6,DHX9,OCIAD1,G3BP2,DHFR,MAEA,GPN1,UBC,HSD17B4,LMNB1,PABPN1" Pubmed 11230166 Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Pubmed 1.78E-06 1.13E-01 1.79E-03 2.08E-02 38 750 "MCC,NDRG2,KIAA1211,RGS5,ARL1,CCNB1IP1,ATP2B4,MYBPC1,CAST,FCHO2,ZNF664,RGSL1,DHRS1,THAP6,MPC2,LYSMD3,DNM3,DDX59,FBXL5,NUDT12,F11R,RNF219,ATG10,SMC6,AASDH,FAM172A,ADGRV1,USP44,PCBD2,UTP15,TOMM40L,LIMCH1,BRD8,ZMYM2,TDRD3,FAM49A,FIP1L1,NUAK2" Pubmed 17353931 Large-scale mapping of human protein-protein interactions by mass spectrometry. Pubmed 1.90E-06 1.20E-01 1.87E-03 2.18E-02 55 1284 "MCC,ULK1,DHX37,MSH2,ARL1,KCTD12,MYH7,NEDD8,ARHGEF7,CCNA1,ODC1,CDK17,CHD1,PIGR,STRN3,POLE,CEP135,EIF2AK2,MATR3,PSMA6,SREK1,DHX9,TBC1D4,G3BP2,RNF219,ATG10,IPO4,TMEM33,LRPPRC,EIF2D,TRIM28,EIF2B1,SAP18,PCBD2,SFSWAP,PAICS,UFM1,WDCP,SF3B6,MRPS14,ACIN1,SNRPF,PDS5B,IQGAP2,STRN,EML4,XPO4,CRB1,MSH6,UBE2K,CENPH,CAB39L,LIG4,CDK2AP1,LTA4H" Cytoband 12q24.33 12q24.33 1.81E-35 3.49E-33 3.49E-33 2.04E-32 30 53 "EP400,FBRSL1,TMEM132D-AS1,ADGRD1,GLT1D1,PIWIL1,NOC4L,GALNT9,PXMP2,LINC01257,FZD10-DT,SNORA49,STX2,SFSWAP,DDX51,ZNF605,TMEM132D,P2RX2,CHFR,PUS1,ANKLE2,GOLGA3,FZD10,RIMBP2,ZNF10,ZNF26,ZNF84,ZNF140,PGAM5,EP400P1" Cytoband 12q23.1 12q23.1 4.04E-32 7.80E-30 3.90E-30 2.28E-29 24 34 "TMPO-AS1,LOC643711,LINC02453,GAS2L3,AMDHD1,SLC5A8,CDK17,CFAP54,MIR135A2,NR1H4,SNORA53,DEPDC4,CCDC38,GOLGA2P5,SCYL2,SNRPF,UHRF1BP1L,NEDD1,IKBIP,ANO4,ACTR6,ANKS1B,RMST,FAM71C" Cytoband 14q12 14q12 4.00E-31 7.72E-29 2.57E-29 1.50E-28 28 56 "NYNRIN,ADCY4,ARHGAP5,STXBP6,MYH6,MYH7,NEDD8,CBLN3,TSSK4,CFL2,DHRS1,HECTD1,AKAP6,HEATR5A,FITM1,NOP9,TINF2,IPO4,DTD2,GMPR2,G2E3,NUBPL,CIDEB,SCFD1,KHNYN,LINC01551,AP4S1,SDR39U1" Cytoband 14q11.2 14q11.2 3.44E-30 6.63E-28 1.66E-28 9.68E-28 43 188 "NDRG2,HOMEZ,CCNB1IP1,CARMIL3,PPP1R3E,NFATC4,AP1G2,PCK2,CEBPE,CPNE6,CMA1,RNASE9,THTPA,NGDN,CMTM5,CTSG,PSME1,PSME2,C14orf119,RABGGTA,RNF31,EMC9,DHRS2,SLC22A17,IRF9,DHRS4-AS1,TM9SF1,ARHGEF40,POTEM,ACIN1,DCAF11,DHRS4,RIPK3,TEP1,SLC7A8,TGM1,GZMH,GZMB,RAB2B,IL25,ZFHX2,RNASE11,PABPN1" Cytoband 12q24.31 12q24.31 2.22E-28 4.29E-26 8.58E-27 5.01E-26 30 81 "LRRC43,TMEM132B,PITPNM2,DHX37,DDX55,AACS,RILPL1,SCARB1,RFLNA,ZNF664,WDR66,BRI3BP,C12orf65,OGFOD2,SBNO1,EIF2B1,MPHOSPH9,TCTN2,ARL6IP4,ZCCHC8,CCDC92,TMED2,LINC00939,KMT5A,SNRNP35,GTF2H3,ATP6V0A2,RILPL2,DNAH10,CDK2AP1" Cytoband 4p16.3 4p16.3 1.05E-22 2.02E-20 3.36E-21 1.97E-20 27 91 "ADD1,UVSSA,NOP14,FAM193A,PDE6B,ZNF595,POLN,FAM53A,DGKQ,PIGG,RGS12,RNF4,MAEA,ABCA11P,PCGF3,TMEM129,SPON2,FGFR3,TACC3,SH3BP2,TMEM175,RNF212,ZBTB49,ZNF721,ZNF876P,NSD2,LETM1" Cytoband 1q32.1 1q32.1 1.72E-15 3.31E-13 4.73E-14 2.76E-13 23 114 "ADORA1,PPFIA4,ATP2B4,PPP1R12B,SYT2,LINC01136,PTPRVP,C1orf116,PM20D1,DDX59,EIF2D,KLHL12,LGR6,FCAMR,LRRN2,PLEKHA6,NR5A2,KIF21B,KDM5B,TMEM183A,NFASC,CNTN2,NUAK2" Cytoband 12q23.2 12q23.2 2.58E-14 4.97E-12 6.22E-13 3.63E-12 11 18 "ARL1,ASCL1,MYBPC1,NUP37,PMCH,GNPTAB,C12orf42,PARPBP,DRAM1,SPIC,IGF1" Cytoband 2p23.3 2p23.3 2.51E-13 4.85E-11 5.39E-12 3.15E-11 17 69 "ADGRF3,UBXN2A,IFT172,SUPT7L,SLC35F6,FAM228A,DNAJC27,CGREF1,WDCP,EFR3B,DRC1,RBKS,GTF3C2,GPN1,SELENOI,MFSD2B,C2orf70" Cytoband 13q12 13q12 1.78E-12 3.44E-10 3.36E-11 1.96E-10 11 24 "MIPEP,ZMYM5,SACS,PCOTH,FLT1,FLT3,SGCG,SACS-AS1,ATP8A2,GJB6,GPR12" Cytoband 19q13.43 19q13.43 1.91E-12 3.69E-10 3.36E-11 1.96E-10 18 89 "CENPBD1P1,ZNF542P,NLRP4,ZNF586,ZNF329,ZNF419,ZNF256,ZNF671,ZNF446,ZNF667,MIMT1,AURKC,ZNF544,ZNF550,NLRP8,ZNF470,ZNF324B,GALP" Cytoband 12q24.3 12q24.3 1.53E-10 2.96E-08 2.46E-09 1.44E-08 6 6 "ULK1,MMP17,POLE,RAN,CLIP1,UBC" Cytoband 4q12 4q12 4.67E-10 9.02E-08 6.94E-09 4.05E-08 13 57 "KIAA1211,SCFD2,PDGFRA,EXOC1L,CLOCK,CEP135,SPATA18,AASDH,REST,PAICS,NMU,GSX2,FIP1L1" Cytoband 13q34 13q34 9.25E-10 1.79E-07 1.28E-08 7.45E-08 13 60 "CUL4A,ATP4B,PROZ,ARHGEF7,DAOA,CHAMP1,GRTP1,DCUN1D2,F7,F10,RASA3,ATP11A,TFDP1" Cytoband 1q23.3 1q23.3 1.49E-09 2.87E-07 1.90E-08 1.11E-07 12 51 "FCGR2C,UHMK1,FCRLB,TSTD1,NOS1AP,NR1I3,RGS4,TOMM40L,CD244,FCRLA,ARHGAP30,CCDC190" Cytoband 13q12.11 13q12.11 1.58E-09 3.04E-07 1.90E-08 1.11E-07 11 41 "MRPL57,MPHOSPH8,CRYL1,SAP18,GJA3,TPTE2,LINC00442,ZDHHC20,EEF1AKMT1,SKA3,MICU2" Cytoband 4p12 4p12 7.74E-09 1.49E-06 8.79E-08 5.13E-07 8 20 "NFXL1,GNPDA2,GABRA2,GABRB1,COX7B2,YIPF7,TXK,GUF1" Cytoband 1q24 1q24 1.23E-08 2.36E-06 1.31E-07 7.67E-07 8 21 "BLZF1,CCDC181,CD84,MPC2,RABGAP1L,SUCO,ADCY10,TNR" Cytoband 4p14 4p14 3.95E-08 7.63E-06 4.02E-07 2.35E-06 10 43 "WDR19,SMIM14,LOC439933,TLR6,TMEM156,RELL1,N4BP2,FAM114A1,TBC1D1,UBE2K" Cytoband 13q11-q12 13q11-q12 2.90E-07 5.60E-05 2.80E-06 1.64E-05 4 4 "LATS2,FGF9,GJB2,ZMYM2" Cytoband 19q13.4 19q13.4 3.06E-07 5.90E-05 2.81E-06 1.64E-05 12 80 "PTPRH,TRIM28,GP6,LILRB1,LILRB4,MZF1,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,ZNF304" Cytoband 14q13.1 14q13.1 7.59E-07 1.47E-04 6.66E-06 3.89E-05 5 9 "PNP,SNX6,EGLN3,EAPP,SPTSSA" Cytoband 14q13.2 14q13.2 1.54E-06 2.97E-04 1.29E-05 7.54E-05 7 26 "RALGAPA1,FAM177A1,PPP2R3C,BRMS1L,SRP54,INSM2,BAZ1A" Cytoband 1q25 1q25 2.03E-06 3.93E-04 1.64E-05 9.56E-05 7 27 "RGSL1,DHX9,TSEN15,FAM129A,RNASEL,NMNAT2,NPL" Cytoband 5q12.3 5q12.3 2.19E-06 4.22E-04 1.69E-05 9.87E-05 6 18 "NLN,SREK1,CWC27,TRAPPC13,ERBIN,MAST4" Cytoband 5q31.1 5q31.1 2.33E-06 4.51E-04 1.73E-05 1.01E-04 10 65 "PITX1,TXNDC15,ETF1,PCBD2,SLC22A4,RAPGEF6,C5orf56,TCF7,IRF1,TRPC7" Cytoband 5q15 5q15 3.82E-06 7.38E-04 2.73E-05 1.60E-04 8 41 "CAST,TTC37,SPATA9,FAM172A,ARSK,FAM81B,ERAP1,NR2F1-AS1" Cytoband 2p25.3 2p25.3 4.39E-06 8.48E-04 3.03E-05 1.77E-04 6 20 "SNTG2,COLEC11,TRAPPC12,SH3YL1,ALKAL2,MYT1L" Cytoband 12q24.32 12q24.32 7.18E-06 1.39E-03 4.62E-05 2.70E-04 5 13 "LINC02347,LINC02372,SLC15A4,LINC02393,LINC00507" Cytoband 1q22-q23 1q22-q23 7.18E-06 1.39E-03 4.62E-05 2.70E-04 5 13 "CD1D,CD1E,DCAF8,NCSTN,ITLN2" Cytoband 12q23 12q23 9.37E-06 1.81E-03 5.84E-05 3.41E-04 4 7 "APAF1,SLC25A3,ELK3,UTP20" Cytoband 5q13.3 5q13.3 1.31E-05 2.53E-03 7.91E-05 4.62E-04 7 35 "CKMT2,FAM169A,RASA1,IQGAP2,POC5,ZBED3-AS1,ANKDD1B" Cytoband 2p21 2p21 1.81E-05 3.49E-03 1.02E-04 5.93E-04 9 65 "MCFD2,MSH2,PREPL,LRPPRC,STPG4,THADA,EML4,LINC01913,TTC7A" Cytoband 2p22-p21 2p22-p21 1.84E-05 3.55E-03 1.02E-04 5.93E-04 4 8 "CAD,NLRC4,EIF2AK2,MEMO1" Cytoband 14q11.2-q12 14q11.2-q12 1.84E-05 3.55E-03 1.02E-04 5.93E-04 4 8 "BCL2L2,LTB4R,EFS,LTB4R2" Cytoband 2p22.2 2p22.2 2.30E-05 4.44E-03 1.23E-04 7.21E-04 5 16 "VIT,NDUFAF7,SULT6B1,CYP1B1-AS1,STRN" Cytoband 2p23 2p23 3.20E-05 6.17E-03 1.67E-04 9.74E-04 5 17 "NCOA1,SLC5A6,DNMT3A,GCKR,KIF3C" Cytoband 5q13.2 5q13.2 4.19E-05 8.08E-03 2.13E-04 1.24E-03 8 56 "BTF3,FCHO2,GUSBP3,MARVELD2,UTP15,MRPS27,ARHGEF28,TMEM174" Cytoband 12q22 12q22 4.57E-05 8.83E-03 2.26E-04 1.32E-03 7 42 "MIR331,NTN4,USP44,VEZT,METAP2,TMPO,LTA4H" Cytoband 1q31-q32 1q31-q32 4.83E-05 9.33E-03 2.33E-04 1.36E-03 3 4 "CDK18,CHIT1,PTPRC" Cytoband 2p24.2 2p24.2 5.32E-05 1.03E-02 2.50E-04 1.46E-03 4 10 "RAD51AP2,SMC6,NT5C1B,FAM49A" Cytoband 1q24.2 1q24.2 6.72E-05 1.30E-02 3.09E-04 1.80E-03 6 31 "MPZL1,POU2F1,METTL11B,GORAB,C1orf112,GPR161" Cytoband 1q25.2 1q25.2 9.72E-05 1.88E-02 4.36E-04 2.55E-03 6 33 "ABL2,ASTN1,FAM163A,CEP350,NPHS2,AXDND1" Cytoband 13q13 13q13 1.19E-04 2.29E-02 5.21E-04 3.04E-03 3 5 "DCLK1,ELF1,NBEA" Cytoband 5q13 5q13 1.24E-04 2.39E-02 5.30E-04 3.10E-03 5 22 "MAP1B,ADGRV1,POLK,GFM2,HEXB" Cytoband 1q32 1q32 1.27E-04 2.44E-02 5.31E-04 3.10E-03 7 49 "MDM4,RAB29,PIK3C2B,PKP1,IL20,CFHR4,TNNT2" Cytoband 13q12.12 13q12.12 1.55E-04 2.99E-02 6.36E-04 3.72E-03 5 23 "ATP12A,CENPJ,C1QTNF9B,RNF17,SPATA13" Cytoband 1q23.2 1q23.2 1.61E-04 3.11E-02 6.48E-04 3.79E-03 6 36 "SLAMF6,ATP1A2,COPA,FCRL6,KCNJ9,SLAMF9" Cytoband 5q23.3 5q23.3 2.36E-04 4.55E-02 9.28E-04 5.42E-03 4 14 "FNIP1,SLC12A2,SLC22A5,ADAMTS19" Cytoband 14q13 14q13 4.02E-04 7.75E-02 1.55E-03 9.05E-03 3 7 "NFKBIA,PSMA6,FOXG1" Cytoband 13q32.1 13q32.1 4.13E-04 7.97E-02 1.56E-03 9.13E-03 4 16 "GPR180,MBNL2,UGGT2,OXGR1" Cytoband 4p16 4p16 5.30E-04 1.02E-01 1.95E-03 1.14E-02 4 17 "FGFRL1,LDB2,GAK,HGFAC" Cytoband 5q15-q21 5q15-q21 5.46E-04 1.05E-01 1.95E-03 1.14E-02 2 2 "PCSK1,CHD1" Cytoband 2p23-p22 2p23-p22 5.46E-04 1.05E-01 1.95E-03 1.14E-02 2 2 "SNX17,SLC8A1" Gene Family 471 CD molecules|Tumor necrosis factor superfamily genenames.org 2.14E-10 5.66E-08 5.66E-08 3.49E-07 36 394 "SLAMF6,CD84,FCRL3,FCGR2C,CD1D,CD1E,PDGFRA,NCR1,FCRL5,FCRL2,PTPRC,F11R,FCAMR,TLR6,FCAR,FCGR2B,FCGR3A,FCGR3B,FGFR3,SDC1,SELP,FLT3,TNFSF13B,CD244,LILRB1,ADAM17,LILRB4,FZD10,IGSF8,IL6ST,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT" Gene Family 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 1.47E-08 3.89E-06 1.94E-06 1.20E-05 22 193 "SLAMF6,CADM3,CD84,FCRL3,FCRLB,NCR1,FCRL5,FCRL2,F11R,KIRREL1,GP6,FCAR,FCGR2B,FCGR3A,FCGR3B,FLT1,FLT3,CD244,CNTN2,FCRLA,FCRL6,KIT" Gene Family 362 Ring finger proteins|WD repeat domain containing genenames.org 8.38E-07 2.22E-04 7.40E-05 4.56E-04 23 262 "WDR35,APAF1,WDR19,WDR66,WDFY2,NUP37,STRN3,COPA,DCAF8,IFT172,DMXL1,WDR1,UTP15,NBEA,DCAF11,KIF21B,NEDD1,STRN,EML4,COP1,TEP1,GTF3C2,WDR36" Coexpression 15902281-TableS1c Human Leukemia_Schoch05_530genes GeneSigDB 3.33E-65 3.35E-61 3.35E-61 3.28E-60 85 225 "IL17D,COG6,MIPEP,CUL4A,ATP12A,ATP4B,STARD13,KCTD12,ATP7B,PROZ,ARHGEF7,CCNA1,PCCA,PCDH9,DCLK1,ZMYM5,RCBTB2,WDFY2,ITGBL1,TM9SF2,MPHOSPH8,BIVM,COG3,DCT,TBC1D4,SACS,RNF219,RB1,ARGLU1,POLR1D,CRYL1,LATS2,GRTP1,MBNL2,DCUN1D2,ELF1,SAP18,DLEU1,F7,F10,N4BP2L2,FGF9,TNFRSF19,PIBF1,FOXO1,FLT1,FLT3,SUPT20H,RASA3,SGCG,NBEA,UFM1,TNFSF13B,UGGT2,MYO16,PDS5B,CENPJ,ATP8A2,GJB6,HSPH1,LRCH1,PCDH17,GJA3,GJB2,ATP11A,MTUS2,GPR12,GPR18,KMT5A,DOCK9,XPO4,RNF17,TFDP1,KLF12,TRPC4,TUBA3C,HTR2A,ZMYM2,TDRD3,CAB39L,DIAPH3,LCP1,LIG4,IFT88,MICU2" Coexpression M8432 Genes within amplicon 12q24 identified in a copy number alterations study of 191 breast tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.12E-22 1.13E-18 5.65E-19 5.53E-18 15 15 "ULK1,MMP17,EP400,NOC4L,POLE,GALNT9,PXMP2,SFSWAP,DDX51,P2RX2,CHFR,PUS1,ANKLE2,GOLGA3,PGAM5" Coexpression 15902281-TableS1e Human Leukemia_Schoch05_1374genes GeneSigDB 7.45E-20 7.49E-16 2.50E-16 2.45E-15 70 581 "MAP1B,MCC,NLN,SEMA6A,SNX24,APC,BTF3,CAMK4,CAST,CCNB1,CDK7,PCSK1,PDE4D,CHD1,PGGT1B,CKMT2,PITX1,HOMER1,CRHBP,SNCAIP,CSNK1G3,TTC37,VCAN,FAM169A,ZFYVE16,MATR3,SREK1,DMXL1,KLHL3,NUDT12,DHFR,RASA1,GUSBP3,EFNA5,TXNDC15,FAM172A,ETF1,FNIP1,POLK,SLC12A2,PKD2L2,SLC22A4,SLC22A5,MEGF10,IQGAP2,ERAP1,MRPS27,KDM3B,MCCC2,ERBIN,BRD8,MAST4,PPIP5K2,ACSL6,TCF7,TGFBI,HEXB,HMGCR,HSD17B4,STARD4,DCP2,YTHDC2,CENPH,IL6ST,IRF1,KCNN2,KIF2A,TRPC7,LMNB1,LOX" Coexpression 19061838-TableS14 Human Viral_Cairo08_227genes GeneSigDB 1.11E-13 1.12E-09 2.79E-10 2.73E-09 33 202 "MATN3,MCFD2,MSH2,NCOA1,SLC5A6,CAD,ODC1,COLEC11,ITSN2,SNX17,DNMT3A,GALNT14,LRPPRC,TRAPPC12,SDC1,FBXO11,SLC8A1,THADA,CGREF1,ALLC,RBKS,GCKR,LPIN1,STRN,PSME4,ADAM17,EML4,EMILIN1,MSH6,GTF3C2,HPCAL1,VRK2,KIF3C" Coexpression 17533364-Table2 Human Brain_Lastowska07_61genes GeneSigDB 3.19E-11 3.21E-07 6.43E-08 6.29E-07 14 40 "TAF1B,ODC1,SNTG2,IFT172,SUPT7L,CLIP4,YPEL5,RBKS,LPIN1,TPO,GPN1,HPCAL1,PLB1,FAM49A" Coexpression M1375 Genes co-amplified within MYCN [GeneID=4613] in primary neuroblastoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.79E-11 9.85E-07 1.64E-07 1.61E-06 14 43 "TAF1B,ODC1,SNTG2,IFT172,SUPT7L,CLIP4,YPEL5,RBKS,LPIN1,TPO,GPN1,HPCAL1,PLB1,FAM49A" Coexpression M1947 "Cis-regulated expression quantitative loci (cis-eQTL) in the liver that contribute to metabolic quantitative traits (weight, fat mass, and plasma glucose and cholesterol levels)." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.70E-10 3.72E-06 5.31E-07 5.20E-06 19 93 "SLAMF6,RGS5,PPFIA4,B4GALT3,PTPRVP,COPA,DCAF8,F11R,RABGAP1L,TSEN15,FCGR2B,HSD17B7,FMO1,IVNS1ABP,MRPS14,TMEM183A,CD244,IGSF8,LAD1" Coexpression M4500 Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.97E-07 3.99E-03 4.99E-04 4.89E-03 59 854 "MAP1B,APBB2,APC,MSH2,FAM193A,NCOA1,ATP2B4,STARD13,ARHGEF7,PCCA,CDK17,CENPC,CHD1,ATAD2B,HOMER1,STRN3,CLOCK,NCOR2,TTC37,ITSN2,CEP135,FAM169A,ZFYVE16,CEP350,SACS,RABGAP1L,RASA1,RB1,LRPPRC,EFNA5,MPHOSPH9,FAM172A,CLIP1,N4BP2L2,PIBF1,SUCO,SUPT20H,LIMCH1,PDS5B,KDM5B,KDM3B,ANKLE2,KLHL20,PSME4,UTP20,ADAM17,PPIP5K2,ADGRA3,DOCK9,TDG,MSH6,GTF3C2,BAZ1A,HPCAL1,ZMYM2,TDRD3,KIF2A,LMNB1,MICU2" Coexpression 17174972-TableS1 Human Zola07_426genes_CellDifferentiationMarkers GeneSigDB 4.78E-07 4.81E-03 5.34E-04 5.23E-03 32 345 "CD84,FCGR2C,CD1D,CD1E,PDGFRA,NCR1,FCRL5,PTPRC,F11R,TLR6,FCAR,FCGR2B,FCGR3A,FCGR3B,FGFR3,SDC1,SELP,FLT3,TNFSF13B,CD244,LILRB1,ADAM17,LILRB4,FZD10,IGSF8,IL6ST,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,KIT" Coexpression 18199535-SuppTable1 Human StemCell_Amundson08_990genes GeneSigDB 6.74E-07 6.78E-03 6.78E-04 6.64E-03 62 930 "MAP1B,BIRC6,APC,MSH2,BLZF1,SLC4A4,ATP2B4,PPP1R12B,RAB29,CAD,CAMK4,CAST,CCNB1,CDK18,PDGFRA,CFL2,CHD1,PGGT1B,ITGBL1,CPNE6,HOMER1,AKAP6,COPA,CLOCK,CSNK1G3,PRKD1,DCT,PTGS2,DHX9,COCH,PTPRC,SACS,RASA1,REST,RGS4,EIF2B1,CWC27,FCGR2B,N4BP2L2,TACC3,PIBF1,FOXO1,FLT1,FMO1,SUPT20H,SLC12A2,TNFSF13B,SLC22A4,IQGAP2,HSPH1,GC,GCKR,NEDD1,GJB2,METAP2,BAZ1A,GZMH,HSP90B1,IL6ST,LAD1,LMNB1,IFT88" Coexpression 18425577-TableS3a Human Breast_Creighton09_594genes GeneSigDB 8.35E-07 8.40E-03 7.64E-04 7.48E-03 37 443 "MATN3,APBB2,WDR19,ARL1,ATP7B,NFATC4,AP1G2,NOVA1,STRN3,KIAA0040,DMXL1,FBXL5,CRYL1,GUSBP3,DHRS2,SAP18,STK32B,GMPR2,F7,ARL6IP4,NBEA,SLC22A5,DCAF11,EAPP,ATP8A2,MRPS27,SRP54,RBKS,MCCC2,MAST4,KHNYN,SNRNP35,SLC7A8,MZF1,IL6ST,SDR39U1,IFT88" Coexpression M2241 Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D Matrigel only. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.81E-06 1.82E-02 1.52E-03 1.49E-02 60 916 "SMIM15,MDM4,MSH2,BLZF1,GAS2L3,ODC1,UHMK1,ZMYM5,CFL2,PGGT1B,STRN3,RCHY1,LYSMD3,C12orf65,UBXN2A,BIVM,FBXL5,CEP350,COCH,SACS,G3BP2,RABGAP1L,TSEN15,RNF219,ARGLU1,REST,DTD2,PACRGL,SBNO1,MPHOSPH9,CWC27,UTP15,N4BP2L2,SUCO,SH3BP2,FBXO11,G2E3,PAICS,IVNS1ABP,N4BP2,SNRPF,CPSF3,PDS5B,RAPGEF6,ZNF274,UHRF1BP1L,ERAP1,KLHL20,STRN,TDG,TFDP1,MSH6,TMPO,ZNF721,VRK2,YTHDC2,SPTSSA,KIF2A,DIAPH3,SKA3" Coexpression M8892 Genes down-regulated in pro-B cells versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 2.29E-06 2.31E-02 1.78E-03 1.74E-02 20 172 "ATP2B4,RAB29,PNP,CDKL2,ODC1,BIVM,FBXL5,FAM129A,POLK,FAM114A1,NAAA,RIPK3,KHNYN,TEP1,KLF12,HMGCR,UBC,HTR2A,STARD4,SELENOI" MicroRNA hsa-miR-493*:mirSVR_highEffct hsa-miR-493*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-62 9.82E-59 9.82E-59 8.99E-58 132 1910 "MAP1B,SMIM15,TMEM132B,ATP6V1G3,ANKRD34B,WDR35,FBRSL1,DDX55,BLZF1,AACS,NCOA1,ZNF542P,ATP2B4,STARD13,ARHGEF7,NFKBIA,NOVA1,CDKL2,FCHO2,UHMK1,ZNF664,PCDH9,ZMYM5,CDK17,CDK18,PDE4D,PDGFRA,ITGBL1,NRXN1,NUP37,ATAD2B,BOD1L1,AKAP6,TAPT1,GNPTAB,TOGARAM2,POU2F1,HEATR5A,CLOCK,ITSN2,FAM169A,DNM3,EIF2AK2,DDX59,ZFYVE16,SPATA18,COG3,DMXL1,NUDT12,COCH,TBC1D4,PTPRC,SACS,NR1H4,B3GLCT,SMC6,FAM228A,DTD2,SLC9C2,NTN4,SETDB2,PACRGL,TXNDC15,RNF4,MBNL2,ELF1,MARVELD2,GP6,ARSK,ETF1,CLIP1,ELOVL7,NDUFAF7,FNIP1,FGF9,RELL1,POLK,FOXO1,SUPT20H,RASA3,NBEA,BRMS1L,NUBPL,PAICS,THADA,CCDC88A,SLC22A5,LIMCH1,GABRA2,MYT1L,KIF21B,RAPGEF6,CENPJ,NAAA,TMEM183A,HSPH1,NPAS3,CMPK2,ERBIN,MIMT1,PPARGC1A,INSM2,ADAM17,PPIP5K2,MTUS2,ADGRL3,ANO4,C5orf56,STON1,DOCK9,TDG,TEP1,TGFBI,MSH6,AP4S1,BAZ1A,HMGCR,TXK,ZNF876P,VRK2,YTHDC2,FCRL6,ZNF10,PLB1,ZMYM2,IRF1,LHX9,ZBED3-AS1,TMEM178A,KIT,TTC41P,LIG4" MicroRNA hsa-miR-2053:mirSVR_highEffct hsa-miR-2053:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.42E-60 3.94E-56 1.97E-56 1.81E-55 130 1943 "RALGAPA1,SFTA3,MAP1B,MDM4,NLN,COG6,WDR35,HOMEZ,APC,BLZF1,NCOA1,SLC4A4,KCTD12,NOVA1,TAF1B,FCHO2,CD1E,PCDH9,ZMYM5,PDE4D,PDGFRA,PIWIL1,RCBTB2,GPR180,ITGBL1,NUP37,THAP6,HOMER1,AKAP6,COPA,FAM53A,PM20D1,LYSMD3,CLOCK,PREPL,CSNK1G3,PRKD1,ZNF586,ZFYVE16,PIGG,SREK1,COG3,PTGS2,DMXL1,FBXL5,KLHL3,NUDT12,CEP120,PTPRC,PPP2R3C,B3GLCT,RB1,DTD2,LAP3,CLIP4,POLR1D,MBNL2,ELF1,BORA,DRAM1,ARSK,ABCA11P,CLIP1,ELOVL7,USP44,TRAPPC13,TMEM156,FCGR2B,UTP15,GORAB,FNIP1,FGFR3,PIBF1,POLK,HSD17B7,FTLP10,VEZT,G2E3,BRMS1L,ALKAL2,UFM1,IVNS1ABP,TADA1,SLC12A2,SLC22A4,NR5A2,ZNF667,GABRA2,JPH4,ZNF274,UHRF1BP1L,ERAP1,OXGR1,MRPS27,RBKS,ANKLE2,IKBIP,COMMD6,PPARGC1A,DHRS4,PSME4,UGT2A1,ATP11A,ADGRL3,STON1,YIPF7,NCSTN,RASSF6,RAB2B,ATP6V0A2,TECRL,SLAIN1,PAPPA2,ZNF10,JCHAIN,SPTSSA,ZMYM2,TDRD3,LMLN,KIF3C,DIAPH3,AMTN,TTC41P,RMST,SPRYD7,AXDND1,LIG4,LMNB1,CDK2AP1,SKA3" MicroRNA hsa-miR-26b:mirSVR_highEffct hsa-miR-26b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.76E-58 3.60E-54 1.20E-54 1.10E-53 118 1627 "ANKRD34B,SEMA6A,ULK1,CUL4A,EP400,UVSSA,APAF1,APC,CENPBD1P1,ATP1A2,SLC4A4,KCTD12,FCRL3,CCNA1,CDKL2,SLC5A8,PCCA,PCDH9,PCK2,ZMYM5,CHD1,WDFY2,NRXN1,ATAD2B,CFAP45,ADGRF3,GNPTAB,HEATR5A,LYSMD3,CLOCK,SNCAIP,DNM3,FCRL5,PIGG,SREK1,PTGS2,DMXL1,CEP350,TBC1D4,F11R,SACS,G3BP2,DHFR,PARPBP,PPP2R3C,FAM129A,RB1,DTD2,RGS4,LAP3,NTN4,GRTP1,BORA,TBC1D19,FAM172A,CWC27,MAEA,ABCA11P,ELOVL7,FCAR,GORAB,FNIP1,N4BP2L2,FGF9,RELL1,PIBF1,SELP,RUBCNL,FBXO11,G2E3,UFM1,SCYL2,IVNS1ABP,CCDC88A,WDCP,SLC22A5,CHFR,LIMCH1,CPSF3,GABRA2,MYT1L,CIDEB,PDS5B,IQGAP2,HSPH1,NPAS3,ERBIN,IKBIP,LPIN1,PPARGC1A,METAP2,MTUS2,GOLGA3,ADGRL3,COP1,TDG,COX18,NT5C1B,MSH6,GTF3C2,ZNF721,ADAMTS19,UBE2K,TRPC4,TENT2,HTR2A,WDR36,DCP2,FCRL6,KCNT2,IL6ST,ANKS1B,FAM49A,LMLN,MFSD2B,SPRYD7,LIG4,CDK2AP1" MicroRNA hsa-miR-875-3p:mirSVR_highEffct hsa-miR-875-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-55 5.89E-52 1.47E-52 1.35E-51 122 1839 "MAP1B,ADD1,SLAMF6,TBC1D14,WDR35,SEMA6A,HOMEZ,FBRSL1,DDX55,BLZF1,NCOA1,ZNF542P,ARHGEF7,NOVA1,MPZL1,CAST,FCHO2,CD1D,UHMK1,PDE4D,CFL2,CHD1,PFKFB2,VIT,ITGBL1,PIK3C2B,UGT2B28,HECTD1,THAP6,AKAP6,RCHY1,HEATR5A,SNCAIP,CSNK1G3,VCAN,FAM169A,DNM3,PRKD1,FCRL5,BIVM,SREK1,DMXL1,LOC439933,DHX9,CEP120,PTPRC,F11R,G3BP2,RABGAP1L,PARPBP,NR1I3,DNMT3A,EGLN3,RASA1,SMC6,AASDH,SETDB2,EIF2D,MBNL2,EIF2B1,KLHL12,LGR6,STX2,ARSK,ETF1,DLEU1,CLIP1,ELOVL7,SH3YL1,TRAPPC13,TOMM40L,N4BP2L2,TNFRSF19,RELL1,PIBF1,FOXO1,VEZT,NBEA,BRMS1L,NUBPL,IVNS1ABP,CCDC88A,ZNF605,N4BP2,ZNF667,LIMCH1,GABRB1,KDM5B,RAPGEF6,MRPS27,CMPK2,ANKLE2,LRCH1,ERBIN,PSME4,PPIP5K2,ADGRL3,GPR12,TCF7,C1QTNF9B,TDG,GPR161,AP4S1,TMPO,HEXB,ADAMTS19,TXK,UGT2B7,PAPPA2,VRK2,HTR2A,NSD2,ZNF470,IL6ST,CCDC169,SPTSSA,LHX9,FAM151B,KIR3DL1,LINC01913,PABPN1,LOX" MicroRNA hsa-miR-30e:mirSVR_highEffct hsa-miR-30e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.45E-52 2.90E-48 5.80E-49 5.31E-48 122 1991 "RALGAPA1,SMIM15,BIRC6,ADD1,KIAA1211,NLN,COG6,PITPNM2,APC,WDR19,BTF3,CCNA1,CAMK4,FCHO2,PCDH9,FAM177A1,PDE4D,PDGFRA,CFL2,CHD1,CCDC122,DHRS1,GPR180,SMIM14,SNX6,ATAD2B,BOD1L1,LTB4R,AKAP6,RCHY1,GNPTAB,HEATR5A,CLOCK,NCOR2,LRRTM2,CEP135,MATR3,SPATA18,DHX9,CEP350,NUDT12,SACS,RABGAP1L,WDR1,PPP2R3C,C14orf119,TSEN15,DNMT3A,RASA1,DTD2,CLIP4,POLR1D,TXNDC15,MBNL2,UGT2A3,ELF1,STX2,DEPDC4,FAM81B,ABCA11P,PCGF3,ELOVL7,SH3YL1,TRAPPC13,FCGR2B,GORAB,RELL1,POLK,FOXG1,MROH9,FOXO1,SUPT20H,VEZT,RUBCNL,FBXO11,UFM1,SLC30A6,C1orf112,SLC22A5,NR5A2,YPEL5,LIMCH1,CYP1B1-AS1,MYO16,GABRB1,JPH4,TMEM183A,ERAP1,ATP8A2,NPAS3,ERBIN,IKBIP,KLHL20,PCDH17,LPIN1,PPARGC1A,MAST4,TBC1D1,PPIP5K2,METAP2,ADGRL3,ADGRA3,ANO4,GPR12,EML4,TDG,TFDP1,CRB1,ACTR6,GUF1,TENT2,PAPPA2,IL25,ZMYM2,FAM49A,CHPT1,LMLN,FIP1L1,LCP1,RMST,AXDND1,LOX" MicroRNA hsa-miR-580:mirSVR_highEffct hsa-miR-580:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.47E-50 5.04E-46 8.39E-47 7.69E-46 114 1808 "MAP1B,SMIM15,NLN,WDR35,HOMEZ,STXBP6,NCOA1,FCRL3,ARHGEF7,CACNA1E,NRL,CAST,FCHO2,FCRLB,PCK2,ZMYM5,FAM177A1,PCSK1,PDGFRA,CHIT1,PGGT1B,ATAD2B,LTB4R,THAP6,TAPT1,GNPTAB,CLOCK,PREPL,LACC1,CSNK1G3,DNM3,UBXN2A,ZNF586,ZFYVE16,SPATA18,SREK1,DMXL1,FBXL5,NUDT12,COCH,TBC1D4,PTPRC,RABGAP1L,TSEN15,EGLN3,FAM129A,RASA1,TMEM161B,SLC9C2,MEMO1,POLR1D,PACRGL,MBNL2,ELF1,DLEU1,DNAJC27,ABCA11P,SH3YL1,IRF9,FNIP1,FGF9,PIBF1,POLK,SELP,FTLP10,SUPT20H,ZCCHC8,NBEA,CCDC92,BRMS1L,ALKAL2,IVNS1ABP,ZNF605,SLC12A2,WDCP,NR5A2,UGGT2,PDS5B,NAAA,ERAP1,NPAS3,NFASC,KLHL20,PCDH17,MIMT1,PPARGC1A,INSM2,ADGRL3,ANO4,EML4,RNF17,BAZ1A,RASSF6,ZNF721,HEXB,HSP90B1,TXK,SLAIN1,HSD17B4,NLRP8,HTR2A,NSD2,YTHDC2,ZNF26,KCNT2,MZF1,TADA2B,ZFHX2,ZNF84,CCDC169,PLB1,FAM151B,ZBED3-AS1,SPRYD7" MicroRNA hsa-miR-1297:mirSVR_highEffct hsa-miR-1297:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.48E-49 1.32E-45 1.89E-46 1.73E-45 97 1274 "ANKRD34B,ULK1,EP400,UVSSA,APAF1,APC,CENPBD1P1,ATP1A2,SLC4A4,FCRL3,CCNA1,SLC5A8,PCCA,PCDH9,PCK2,ZMYM5,NRXN1,ATAD2B,CFAP45,ADGRF3,HEATR5A,SNCAIP,DNM3,FCRL5,PIGG,SREK1,PTGS2,DMXL1,CEP350,TBC1D4,SACS,G3BP2,DHFR,PARPBP,PPP2R3C,FAM129A,RB1,DTD2,RGS4,LAP3,NTN4,GRTP1,TBC1D19,FAM172A,CWC27,MAEA,ABCA11P,ELOVL7,FCAR,GORAB,FNIP1,N4BP2L2,FGF9,RELL1,PIBF1,SELP,RUBCNL,FBXO11,G2E3,UFM1,SCYL2,IVNS1ABP,CCDC88A,SLC22A5,CHFR,LIMCH1,CPSF3,GABRA2,MYT1L,PDS5B,HSPH1,NPAS3,IKBIP,PPARGC1A,METAP2,GOLGA3,COP1,TDG,COX18,NT5C1B,MSH6,GTF3C2,ZNF721,ADAMTS19,UBE2K,TRPC4,TENT2,HTR2A,WDR36,FCRL6,IL6ST,ANKS1B,FAM49A,LMLN,MFSD2B,SPRYD7,CDK2AP1" MicroRNA hsa-miR-30c:mirSVR_highEffct hsa-miR-30c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.19E-49 3.29E-45 4.11E-46 3.77E-45 117 1948 "RALGAPA1,SMIM15,BIRC6,ADD1,KIAA1211,NLN,COG6,HOMEZ,PITPNM2,WDR19,KCTD12,BTF3,CCNA1,CAMK4,FCHO2,CD1D,PCDH9,PCSK1,PDE4D,PDGFRA,CFL2,CHD1,DHRS1,GPR180,SMIM14,SNX6,ATAD2B,BOD1L1,HOMER1,AKAP6,RCHY1,HEATR5A,CLOCK,LRRTM2,CEP135,MATR3,SREK1,DHX9,CEP350,NUDT12,SACS,RABGAP1L,WDR1,TSEN15,DNMT3A,ATG10,RASA1,DTD2,CLIP4,POLR1D,CRYL1,TXNDC15,MBNL2,UGT2A3,ELF1,STX2,DEPDC4,FAM81B,ABCA11P,PCGF3,ELOVL7,SH3YL1,TRAPPC13,FCGR2B,FGF9,RELL1,FOXG1,MROH9,SUPT20H,RUBCNL,FBXO11,UFM1,IVNS1ABP,C1orf112,SLC22A5,NR5A2,YPEL5,LIMCH1,CYP1B1-AS1,MYO16,GABRB1,JPH4,TMEM183A,ERAP1,ATP8A2,NPAS3,ERBIN,IKBIP,KLHL20,PCDH17,PPARGC1A,MAST4,ZNF544,TBC1D1,PPIP5K2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,CRB1,ACTR6,ADAMTS19,GUF1,TENT2,IL25,ZMYM2,FAM49A,LMLN,FIP1L1,LCP1,RMST,SPRYD7,AXDND1,LOX" MicroRNA hsa-miR-582-5p:mirSVR_highEffct hsa-miR-582-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.90E-49 4.20E-45 4.67E-46 4.27E-45 114 1847 "NDRG2,HOMEZ,CUL4A,APC,BLZF1,STARD13,KCTD12,NOVA1,CACNA1E,CBLN3,CAST,FCHO2,PCSK1,PDGFRA,PDE6B,CFL2,VIT,PGGT1B,C1orf116,AKAP6,STRN3,TAPT1,RCHY1,LYSMD3,PREPL,VCAN,C12orf65,LRRTM2,DNM3,ZFYVE16,IFT172,COG3,PTGS2,SUPT7L,C14orf119,NR1H4,RASA1,RB1,SLC9C2,CLIP4,MEMO1,PACRGL,TXNDC15,ELF1,TBC1D19,GP6,DRAM1,SAP18,MAEA,ABCA11P,ADGRV1,GORAB,N4BP2L2,FGF9,RELL1,POLK,SUCO,FOXG1,FOXO1,FLT1,FMO1,VEZT,RUBCNL,FBXO11,PLEKHA6,ARHGEF40,SLC12A2,C1orf112,NR5A2,YPEL5,CHFR,LIMCH1,MYO16,GABRA2,MYT1L,PDS5B,KDM5B,IQGAP2,HSPH1,NPAS3,MCCC2,ERBIN,KLHL20,COMMD6,PSME4,UGT2A1,TMED2,PPIP5K2,ADGRL3,ADGRA3,ANO4,EML4,YIPF7,TDG,CRB1,LINC01551,AP4S1,BAZ1A,ACTR6,RIMBP2,ZNF721,NPL,HMGCR,SLAIN1,KCNT2,ZNF140,ZMYM2,IRF1,LHX9,FAM151B,DNAH10,LINC00442,SPRYD7,ZNF304" MicroRNA hsa-miR-26a:mirSVR_highEffct hsa-miR-26a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.10E-48 2.18E-44 2.18E-45 2.00E-44 102 1473 "ANKRD34B,ULK1,EP400,APAF1,APC,CENPBD1P1,ATP1A2,SLC4A4,KCTD12,FCRL3,CCNA1,CDKL2,SLC5A8,PCCA,PCDH9,PCK2,ZMYM5,CFL2,NRXN1,ATAD2B,CFAP45,ADGRF3,HEATR5A,CLOCK,DNM3,FCRL5,PIGG,SREK1,PTGS2,DMXL1,CEP350,TBC1D4,F11R,SACS,G3BP2,DHFR,PARPBP,PPP2R3C,FAM129A,RB1,DTD2,RGS4,LAP3,NTN4,GRTP1,TBC1D19,STX2,FAM172A,CWC27,MAEA,ABCA11P,ELOVL7,FCAR,GORAB,FNIP1,N4BP2L2,FGF9,RELL1,PIBF1,SELP,FBXO11,G2E3,UFM1,SCYL2,IVNS1ABP,CCDC88A,SLC22A5,CHFR,LIMCH1,CPSF3,GABRA2,CIDEB,PDS5B,HSPH1,NPAS3,IKBIP,LPIN1,PPARGC1A,METAP2,GOLGA3,COP1,TDG,COX18,NT5C1B,MSH6,GTF3C2,ZNF721,HEXB,ADAMTS19,UBE2K,TRPC4,TENT2,HTR2A,FCRL6,KCNT2,IL6ST,ANKS1B,FAM49A,LMLN,MFSD2B,SPRYD7,CDK2AP1" MicroRNA hsa-miR-587:mirSVR_highEffct hsa-miR-587:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-47 7.43E-44 6.76E-45 6.19E-44 111 1796 "ATP6V1G3,COG6,DHX37,ARL1,CCDC181,SLC4A4,ATP2B4,DAOA,CAST,ODC1,FCHO2,SCARB1,PCDH9,ZMYM5,CENPC,CFAP54,NRXN1,LINC01085,ADGRF3,HOMER1,COPA,POU2F1,CSNK1G3,CEP135,DNM3,UBXN2A,PRKD1,FCRL5,GLT8D2,SREK1,COG3,DMXL1,NUDT12,PTPRC,PARPBP,TSEN15,RNF219,NR1H4,ZNF419,LRPPRC,MARVELD2,BORA,FAM172A,DRAM1,ABCA11P,TOMM40L,FNIP1,N4BP2L2,TNFRSF19,FGFR3,RELL1,PIBF1,POLK,SUCO,FOXO1,HSD17B7,STAB2,SUPT20H,VEZT,FBXO11,G2E3,SLC8A1,ARHGEF40,TADA1,CCDC88A,SLC12A2,PKD2L2,N4BP2,ACIN1,MEGF10,GABRA2,MYT1L,PDS5B,NMNAT2,RAPGEF6,NAAA,CD244,HSPH1,ERBIN,PCDH17,NMU,PPARGC1A,GJA3,TBC1D1,INSM2,ADAM17,PPIP5K2,METAP2,ADGRL3,ADGRA3,ACSL6,NT5C1B,GZMH,ZNF721,HEXB,ADAMTS19,SLAIN1,NSD2,ZNF10,ZNF140,SPTSSA,ZMYM2,IRF1,ZBED3-AS1,KCNN2,CAB39L,AMTN,TTC41P,LIG4,PABPN1,ZNF304" MicroRNA hsa-miR-630:mirSVR_lowEffct hsa-miR-630:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-47 1.17E-43 9.72E-45 8.90E-44 115 1946 "BIRC6,TMEM132B,ADD1,KIAA1211,ANKRD34B,WDR35,HOMEZ,MCFD2,APAF1,APBB2,APC,MSH2,ARHGAP5,FAM193A,ATP1A2,CARMIL3,BCL2L2,ARHGEF7,PNP,MPZL1,FCHO2,FAM177A1,PDE4D,PDGFRA,CENPC,PDE6B,WDFY2,NRXN1,SNX6,ADGRF3,THAP6,STRN3,RCHY1,RNASE9,SYCP3,LYSMD3,ITSN2,CEP135,UBXN2A,FCRL2,MATR3,NUDT12,TBC1D4,OCIAD1,RABGAP1L,MTX3,SUPT7L,SLC35F6,RNF219,RAN,RASA1,SMC6,FAM228A,RGS4,NTN4,PACRGL,MBNL2,ELF1,MPHOSPH9,MARVELD2,ARSK,PCGF3,CLIP1,TRAPPC13,PIBF1,SUCO,FOXO1,HSD17B7,RASA3,TM9SF1,RUBCNL,FBXO11,UFM1,SLC30A6,THADA,CCDC88A,ZNF605,SLC12A2,PKD2L2,SLC22A5,FSHR,ZNF667,FAM114A1,RAPGEF6,CENPJ,NPAS3,SRP54,RBKS,GJA3,GJB2,PSME4,METAP2,ANO4,TCF7,ARHGEF28,DOCK9,RNF17,TEP1,CRB1,ZBTB49,RASSF6,ATP6V0A2,GUF1,NSD2,ZNF26,ZNF84,SELENOI,CCDC169,PLB1,ZBTB41,KCNN2,LINC00442,AXDND1,LMNB1,PABPN1" MicroRNA hsa-miR-1244:mirSVR_highEffct hsa-miR-1244:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.32E-47 2.30E-43 1.69E-44 1.55E-43 98 1383 "BIRC6,APC,ARL1,ATP4B,CADM3,NOVA1,CDKL2,MPZL1,CD1D,ZMYM5,FAM177A1,CDK17,PDE6B,WDFY2,CFAP54,NRXN1,THAP6,STRN3,GNPTAB,POU2F1,DNM3,GLT8D2,ZFYVE16,SPATA18,LOC439933,NUDT12,CEP120,G3BP2,RABGAP1L,PARPBP,TSEN15,DNMT3A,EGLN3,FAM129A,RASA1,RB1,TMEM161B,AASDH,SLC9C2,RGS4,PACRGL,ELF1,MARVELD2,BORA,CWC27,SAP18,ETF1,USP44,NDUFAF7,FNIP1,PIBF1,POLK,SUCO,FOXO1,FTLP10,FBXO11,CCDC88A,PKD2L2,TMEM132D,MRPS14,YPEL5,CYP1B1-AS1,GABRA2,PDS5B,CENPJ,NAAA,TMEM183A,OXGR1,SRP72,LRCH1,ERBIN,KLHL20,PPARGC1A,UTP20,ATP11A,ADAM17,GPR12,GPR18,C1QTNF9B,NT5C1B,LINC01551,TMPO,MAEL,HSP90B1,GUF1,WDR36,NSD2,KCNT2,C12orf73,PLB1,SPTSSA,ZMYM2,KCNN2,ANKDD1B,SPRYD7,AXDND1,IFT88,LOX" MicroRNA hsa-miR-466:mirSVR_highEffct hsa-miR-466:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.44E-47 2.36E-43 1.69E-44 1.55E-43 114 1924 "RALGAPA1,UVSSA,ARHGAP5,NOP14,ASCL1,CENPBD1P1,SLC4A4,ZNF542P,STARD13,ARHGEF7,NFKBIA,NOVA1,CDKL2,RILPL1,CHAMP1,CD1D,PCDH9,FAM177A1,CDK17,PDGFRA,CFL2,RCBTB2,VIT,SLC25A3,PKP1,JAKMIP1,HOMER1,AKAP6,STRN3,CLOCK,VCAN,CEP135,ZFYVE16,COG3,PTGS2,DMXL1,KLHL3,TBC1D4,CEP120,PTPRC,SACS,GNPDA2,C14orf119,NR1H4,RASA1,SMC6,RGS4,LAP3,RGS12,CLIP4,NTN4,MBNL2,EIF2B1,FAM172A,EFS,ETF1,TRAPPC13,NDUFAF7,GORAB,TNFRSF19,RELL1,PIBF1,POLK,FOXG1,SUPT20H,FBXO11,G2E3,BRMS1L,NUBPL,MBIP,UFM1,TADA1,CCDC88A,SLC12A2,GABRA2,MYT1L,FAM114A1,NAAA,ZNF274,ERAP1,HSPH1,NPAS3,CMPK2,SRP72,NEDD1,ERBIN,IKBIP,COMMD6,BRD8,MTUS2,ADGRL3,ADGRA3,ANO4,EML4,TDG,RNF17,TEP1,LINC01551,ACTR6,ADAMTS19,HSP90B1,TXK,GUF1,HPCAL1,STARD4,YTHDC2,KCNT2,PLB1,LHX9,ZBED3-AS1,ANKDD1B,KIT,IFT88,PABPN1" MicroRNA hsa-miR-200a*:mirSVR_lowEffct hsa-miR-200a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-46 6.62E-43 4.41E-44 4.04E-43 107 1698 "BIRC6,ATP6V1G3,ANKRD34B,SEMA6A,APC,MSH2,ASCL1,AACS,KCTD12,BCL2L2,PROZ,ARHGEF7,RAB29,PNP,CDKL2,CAST,NFXL1,SNTG2,SLC5A8,PCDH9,DCLK1,PDE6B,PIWIL1,CCDC122,WDFY2,JAKMIP1,STRN3,TOGARAM2,LYSMD3,CLOCK,SNCAIP,BRI3BP,IL20,CSNK1G3,VCAN,C12orf65,LRRTM2,CEP135,DNM3,SREK1,CEP350,KLHL3,PTPRC,F11R,SUPT7L,RB1,SMC6,LAP3,TMEM33,CLIP4,SETDB2,EIF2D,EIF2B1,SNORA53,ELF1,GP6,ARSK,STK32B,CLIP1,TRAPPC13,PCBD2,TNFRSF19,FLT1,BRMS1L,UFM1,SCYL2,CCDC88A,PKD2L2,TMEM132D,N4BP2,CHFR,UGGT2,MEGF10,MYT1L,KIF21B,NMNAT2,NAAA,MRPS27,PCDH17,PPARGC1A,PPIP5K2,GOLGA3,CNTN2,ADGRL3,AP4S1,RASSF6,NPL,HEXB,ARHGAP30,GUF1,UGT2B7,SLAIN1,HTR2A,STARD4,SELENOI,IL6ST,ZMYM2,ZBTB41,LHX9,CHPT1,TMEM178A,KCNN2,FIP1L1,KIF3C,DNAH10,LMNB1,MICU2" MicroRNA hsa-miR-30a:mirSVR_highEffct hsa-miR-30a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.47E-46 1.84E-42 1.15E-43 1.05E-42 111 1857 "RALGAPA1,SMIM15,BIRC6,ADD1,KIAA1211,NLN,PITPNM2,APC,WDR19,BCL2L2,BTF3,CCNA1,CAMK4,FCHO2,PCDH9,PDE4D,CFL2,CHD1,DHRS1,GPR180,SMIM14,SNX6,ATAD2B,BOD1L1,LTB4R,AKAP6,RCHY1,GNPTAB,HEATR5A,CLOCK,CSNK1G3,LRRTM2,CEP135,MATR3,SREK1,DHX9,CEP350,NUDT12,SACS,RABGAP1L,WDR1,PPP2R3C,TSEN15,DNMT3A,RASA1,DTD2,CLIP4,POLR1D,TXNDC15,MBNL2,UGT2A3,ELF1,STX2,DEPDC4,FAM81B,ABCA11P,PCGF3,ELOVL7,SH3YL1,TRAPPC13,FCGR2B,GORAB,RELL1,FOXG1,MROH9,SUPT20H,RUBCNL,FBXO11,UFM1,C1orf112,SLC22A5,NR5A2,YPEL5,LIMCH1,CYP1B1-AS1,MYO16,GABRB1,JPH4,TMEM183A,ERAP1,ATP8A2,NPAS3,IKBIP,KLHL20,PCDH17,PPARGC1A,MAST4,TBC1D1,PPIP5K2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,CRB1,ACTR6,GUF1,TENT2,PAPPA2,IL25,ZMYM2,FAM49A,LMLN,FIP1L1,LCP1,RMST,SPRYD7,AXDND1,LOX" MicroRNA hsa-miR-448:mirSVR_lowEffct hsa-miR-448:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.84E-46 2.04E-42 1.15E-43 1.05E-42 111 1859 "MDM4,NDRG2,KIAA1211,APBB2,APC,BLZF1,ARHGAP5,ARL1,NOP14,FAM193A,AACS,SLC4A4,ARHGEF7,TAF1B,FCHO2,LDB2,CCNB1,DCLK1,FAM177A1,CDK7,RGSL1,PFKFB2,VIT,ITGBL1,BOD1L1,ADGRF3,AKAP6,RCHY1,GNPTAB,LYSMD3,CLOCK,IL20,ITSN2,KIAA0040,EIF2AK2,FCRL2,SPATA18,SREK1,PTGS2,CEP120,F11R,SACS,G3BP2,GNPDA2,SUPT7L,WDR1,PARPBP,AASDH,LAP3,POLR1D,NTN4,PACRGL,EFNA5,ELK3,MPHOSPH9,DHRS2,ETF1,PCGF3,CLIP1,F7,TMEM156,PIBF1,FLT3,SUPT20H,RUBCNL,FBXO11,PLEKHA6,SLC30A6,SCYL2,ARHGEF40,ZNF605,CGREF1,C1orf112,UGGT2,SNRPF,MYO16,MEGF10,MYT1L,GABRB1,ERAP1,DRC1,NEDD1,ANKLE2,ERBIN,KLHL20,PPARGC1A,SCFD1,ADGRL3,ADGRA3,EML4,TDG,COX18,RNF17,TFDP1,GTF2H3,RIMBP2,ATP6V0A2,ADAMTS19,ZNF876P,TENT2,NLRP8,HTR2A,ZNF84,SELENOI,PLB1,CCDC190,TMEM178A,KCNJ9,LMLN,FIP1L1,EP400P1" MicroRNA hsa-miR-30b:mirSVR_highEffct hsa-miR-30b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.90E-46 2.07E-42 1.15E-43 1.05E-42 112 1895 "RALGAPA1,SMIM15,BIRC6,ADD1,KIAA1211,NLN,COG6,PITPNM2,APC,WDR19,KCTD12,BTF3,CCNA1,CAMK4,FCHO2,LDB2,CD1D,PCDH9,PCSK1,PDE4D,CFL2,CHD1,DHRS1,GPR180,SMIM14,SNX6,ATAD2B,BOD1L1,HOMER1,AKAP6,RCHY1,CLOCK,LRRTM2,CEP135,MATR3,SREK1,DHX9,CEP350,NUDT12,SACS,RABGAP1L,WDR1,TSEN15,DNMT3A,ATG10,RASA1,DTD2,CLIP4,POLR1D,TXNDC15,MBNL2,UGT2A3,ELF1,STX2,DEPDC4,FAM81B,ABCA11P,PCGF3,ELOVL7,SH3YL1,TRAPPC13,FCGR2B,RELL1,FOXG1,MROH9,SUPT20H,RUBCNL,FBXO11,UFM1,IVNS1ABP,C1orf112,SLC22A5,NR5A2,YPEL5,LIMCH1,CYP1B1-AS1,MYO16,GABRB1,JPH4,TMEM183A,ERAP1,ATP8A2,NPAS3,ERBIN,IKBIP,KLHL20,PCDH17,PPARGC1A,MAST4,ZNF544,TBC1D1,PPIP5K2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,CRB1,GUF1,TENT2,IL25,ZMYM2,FAM49A,LMLN,FIP1L1,LCP1,RMST,SPRYD7,AXDND1,LOX" MicroRNA hsa-miR-802:mirSVR_highEffct hsa-miR-802:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.11E-46 2.19E-42 1.15E-43 1.05E-42 113 1932 "ACOX3,KIAA1211,NLN,COG6,TBC1D14,CUL4A,EP400,APC,WDR19,ARHGAP5,PNP,NRL,MPZL1,CHAMP1,CD1D,SLC5A8,PCDH9,CDK17,CFL2,CHD1,CCDC122,SMIM14,HECTD1,STRN3,TAPT1,CSNK1G3,TTC37,DNM3,UBXN2A,MPHOSPH8,ZFYVE16,MATR3,BIVM,SREK1,COG3,PTGS2,FBXL5,NUDT12,PTPRC,G3BP2,DHFR,PXMP2,NR1H4,RAN,B3GLCT,RASA1,RB1,SLC9C2,CLIP4,RNASEL,LATS2,MBNL2,SNORA53,ARSK,USP44,TRAPPC13,GORAB,FGF9,PIBF1,SDC1,MROH9,VEZT,G2E3,NUBPL,PAICS,UFM1,IVNS1ABP,SLC8A1,TADA1,CCDC88A,SLC12A2,PKD2L2,SLC15A4,ZNF667,TMEM183A,ZNF274,IQGAP2,NPAS3,MRPS27,NFASC,SRP72,NEDD1,KLHL20,PPARGC1A,GJB2,BRD8,MAST4,PPIP5K2,MTUS2,ADGRL3,ADGRA3,ANO4,TDG,COX18,NT5C1B,RAB2B,HEXB,GUF1,SLAIN1,ZNF876P,PAPPA2,FCRL6,ZNF10,ZMYM2,LHX9,FAM151B,CHPT1,KCNN2,EP400P1,RNASE11,TTC41P,LCP1,PABPN1" MicroRNA hsa-miR-1305:mirSVR_highEffct hsa-miR-1305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.11E-46 3.78E-42 1.89E-43 1.73E-42 111 1871 "ACOX3,NLN,UVSSA,FAM193A,NCOA1,MYBPC1,ARHGEF7,NOVA1,FCHO2,MORN2,CHAMP1,CD1D,ZNF664,PCDH9,RGSL1,PGGT1B,WDFY2,SLC25A3,SNX6,THAP6,HOMER1,STRN3,TAPT1,COPA,RCHY1,HEATR5A,LYSMD3,CLOCK,PREPL,LRRTM2,UBXN2A,ZFYVE16,DMXL1,CEP350,TBC1D4,PTPRC,SACS,G3BP2,RASA1,ARGLU1,ZNF329,DTD2,POLR1D,NTN4,LRPPRC,PACRGL,MBNL2,CWC27,MAEA,ETF1,DNAJC27,ABCA11P,ADGRV1,CLIP1,TRAPPC13,PCBD2,GORAB,FNIP1,TNFRSF19,RELL1,SUCO,VEZT,G2E3,UFM1,THADA,TADA1,SLC12A2,PKD2L2,C1orf112,CHFR,UGGT2,GABRA2,GABRB1,NAAA,UHRF1BP1L,OXGR1,NPAS3,MRPS27,CMPK2,MCCC2,NMU,PPARGC1A,PSME4,ADAM17,COX7B2,METAP2,C5orf56,EML4,RNF212,FCRLA,TFDP1,CRB1,TGFBI,LINC01551,TMPO,ZNF721,ATP6V0A2,HSP90B1,GPN1,HMGCR,GUF1,UGT2B7,HSD17B4,ZNF140,ZMYM2,FAM49A,FIP1L1,KIF3C,AXDND1,LIG4,PABPN1" MicroRNA hsa-miR-1299:mirSVR_highEffct hsa-miR-1299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.21E-46 4.90E-42 2.33E-43 2.14E-42 112 1912 "SFTA3,MAP1B,MDM4,TMEM132B,ACOX3,KIAA1211,NLN,WDR35,HOMEZ,CUL4A,FBRSL1,DDX55,BCL2L2,ARHGEF7,BTF3,CCNA1,DAOA,TAF1B,CAST,CHAMP1,CD1D,PCSK1,PDE4D,PDGFRA,CFL2,PFKFB2,ITGBL1,CFAP54,LINC01085,ATAD2B,ADGRF3,THAP6,AKAP6,RCHY1,TOGARAM2,SNCAIP,IL20,CSNK1G3,UBXN2A,BIVM,COG3,PTGS2,PTPRC,F11R,G3BP2,DHFR,TSEN15,NR1I3,DNMT3A,EGLN3,RASA1,SMC6,AASDH,POLR1D,SETDB2,EIF2D,MBNL2,EIF2B1,ZNF256,KLHL12,LGR6,STX2,EFS,ARSK,ETF1,ADGRV1,ELOVL7,TNFRSF19,SUCO,FOXO1,BRMS1L,ALKAL2,NUBPL,IVNS1ABP,CCDC88A,ZNF605,N4BP2,WDCP,SLC22A4,UGGT2,LIMCH1,GABRA2,PDS5B,TMEM183A,LRCH1,PSME4,UGT2A1,ADAM17,PPIP5K2,ANO4,GPR12,TCF7,NCSTN,CRB1,GPR161,ACTR6,TMPO,RIMBP2,HAL,HEXB,GPN1,TXK,VRK2,NSD2,ZNF470,IL6ST,CCDC169,PLB1,SPTSSA,LHX9,CHPT1,MICU2" MicroRNA hsa-miR-33b:mirSVR_lowEffct hsa-miR-33b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-45 6.09E-42 2.77E-43 2.54E-42 114 1989 "MDM4,BIRC6,KIAA1211,SLAMF6,TBC1D14,APC,FAM193A,PPP1R12B,CCNA1,NOVA1,PNP,CDKL2,TAF1B,CD1D,PCDH9,CDK7,PCSK1,PDGFRA,CCDC122,WDFY2,ITGBL1,CFAP54,NRXN1,STRN3,MPC2,COPA,GNPTAB,POU2F1,EPGN,LYSMD3,CSNK1G3,TTC37,C12orf65,DNM3,FCRL5,DCAF8,MATR3,PTGS2,DHX9,CEP350,PXMP2,LINC01257,FAM129A,B3GLCT,AASDH,SETDB2,MBNL2,ELF1,LGR6,ZNF671,STK32B,ABCA11P,F7,GORAB,TNFRSF19,PEAR1,FLT1,VEZT,FBXO11,MBIP,TADA1,ZNF605,SLC12A2,C1orf112,NR5A2,LIMCH1,SNRPF,MEGF10,MYT1L,GABRB1,PDS5B,FAM114A1,JPH4,RAPGEF6,ATP8A2,NPAS3,CMPK2,NFASC,GC,ERBIN,KLHL20,COMMD6,PPARGC1A,MAST4,TMED2,ADGRL3,ADGRA3,ANO4,RNF17,ZBTB49,AP4S1,ACTR6,RIMBP2,ZNF721,ADAMTS19,TRPC4,TECRL,SLAIN1,TENT2,VRK2,YTHDC2,KCNT2,JCHAIN,PLB1,CCDC190,ANKS1B,ZBTB41,NPHS2,TMEM178A,KCNN2,TTC41P,LCP1,TTC7A,CDK2AP1" MicroRNA hsa-miR-544:mirSVR_highEffct hsa-miR-544:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-45 6.55E-42 2.85E-43 2.61E-42 113 1954 "LRRC43,BIRC6,SEMA6A,HOMEZ,FBRSL1,CDKL4,DDX55,BLZF1,ARL1,FAM193A,AACS,NCOA1,ATP12A,STARD13,NFATC4,ARHGEF7,NOVA1,DAOA,SNTG2,PCCA,PCDH9,PCK2,PCSK1,RGSL1,PDGFRA,CENPC,ITGBL1,UGT2B28,THAP6,AKAP6,HEATR5A,LYSMD3,PREPL,LRRTM2,CEP135,PRKD1,EIF2AK2,PIGG,SREK1,COG3,DMXL1,LOC439933,COCH,SACS,RABGAP1L,WDR1,PARPBP,PPP2R3C,NR1H4,B3GLCT,TMEM161B,DTD2,POLR1D,SETDB2,GUSBP3,PACRGL,EFNA5,TXNDC15,MBNL2,LGR6,STX2,DRAM1,STK32B,ETF1,GMPR2,NDUFAF7,N4BP2L2,FGF9,PIBF1,FOXO1,FBXO11,BRMS1L,THADA,UGGT2,MEGF10,MYT1L,GABRB1,TMEM183A,ERAP1,HSPH1,NPAS3,NFASC,SRP72,RBKS,MCCC2,KLHL20,SULT1E1,STRN,MAST4,ZNF544,ATP11A,COX7B2,ADGRL3,ANO4,TCF7,RNF17,CRB1,SLC7A8,TGFBI,AP4S1,TPO,ADAMTS19,STARD4,NSD2,KCNT2,PLB1,ZMYM2,ZBTB41,LINC00272,FIP1L1,DNAH10,AXDND1,ZNF304" MicroRNA hsa-miR-888:mirSVR_lowEffct hsa-miR-888:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.91E-45 3.14E-41 1.31E-42 1.20E-41 113 1986 "RALGAPA1,SFTA3,ADD1,SEMA6A,MCFD2,PPFIA4,APBB2,MSH2,ARHGAP5,NOP14,FAM193A,NCOA1,ZNF542P,ATP2B4,PPP1R12B,CACNA1E,CAST,ODC1,CHAMP1,SNTG2,ZNF664,DCLK1,XPR1,CENPC,WDFY2,TM9SF2,NRXN1,PIK3C2B,ATAD2B,PKP1,FAM163A,GNPTAB,PM20D1,EPGN,BRI3BP,LACC1,CSNK1G3,DNM3,ZNF586,MATR3,TBC1D4,GNPDA2,DNMT3A,RAN,EGLN3,B3GLCT,RNF31,AASDH,RGS12,CRYL1,LRPPRC,PACRGL,RNASEL,DCUN1D2,SNORA53,ELK3,MPHOSPH9,STX2,SAP18,ELOVL7,SH3YL1,TRAPPC13,IRF9,FGFR3,POLK,SUCO,FOXO1,HSD17B7,STAB2,RUBCNL,FBXO11,SCYL2,SLC12A2,TMEM132D,N4BP2,C1orf112,UGGT2,SNRPF,PDS5B,TMEM183A,OXGR1,NFASC,ANKLE2,LRCH1,KLHL20,PCDH17,LPIN1,GJA3,ZNF544,METAP2,MTUS2,GOLGA3,ARHGEF28,STON1,COX18,CRB1,RASSF6,FZD10,HEXB,UBE2K,SLAIN1,NLRP8,PAPPA2,DCP2,IGF1,TADA2B,ZNF470,ANKS1B,LMLN,KIF2A,LINC01913,LETM1,SPRYD7" MicroRNA hsa-miR-148a*:mirSVR_lowEffct hsa-miR-148a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-44 7.79E-41 3.12E-42 2.85E-41 112 1968 "MAP1B,NLN,NYNRIN,TBC1D14,CUL4A,SNX24,APAF1,CDKL4,BLZF1,CCDC181,SLC4A4,CCNA1,LINC02347,PNP,MORN2,PAH,ZNF664,ZMYM5,PDE4D,CFL2,CHD1,CCDC122,CHIT1,WDFY2,SLC25A3,MRPL57,CPNE6,SMIM14,BOD1L1,JAKMIP1,PTPRVP,MPC2,RCHY1,POU2F1,LYSMD3,C12orf65,LRRTM2,DNM3,KIAA0040,FCRL5,SNX17,BIVM,KLHL3,TBC1D4,F11R,GNPDA2,RNF219,FAM129A,ATG10,RASA1,ARGLU1,SMC6,AASDH,TMEM33,CLIP4,GUSBP3,MBNL2,MARVELD2,TBC1D19,ABCA11P,ADGRV1,PCGF3,IRF9,FCAR,TNFRSF19,PIBF1,POLK,SUCO,FOXG1,BRMS1L,MBIP,SLC8A1,ARHGEF40,EFR3B,PUS1,LIMCH1,DCAF11,MYT1L,NMNAT2,ZNF274,GJB6,SRP54,NFASC,ERBIN,KLHL20,ACSL6,KMT5C,DOCK9,XPO4,RNF17,GRSF1,SLC7A8,TMPO,ZNF721,HAL,NPL,ADAMTS19,ZNF876P,DCP2,ZNF26,KCNT2,JCHAIN,ZNF84,CCDC169,ZBTB41,FAM151B,LMLN,KIF2A,KIR2DL4,NUAK2,LMNB1,SKA3" MicroRNA hsa-miR-500:mirSVR_lowEffct hsa-miR-500:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-44 9.47E-41 3.64E-42 3.34E-41 110 1899 "MDM4,TMEM132B,ADD1,SEMA6A,HOMEZ,DDX55,ARHGAP5,NOP14,ASTN1,ATP12A,NFATC4,LINC02347,RAB29,CAST,LDB2,PCDH9,PCK2,CENPC,GLT1D1,PDE6B,VIT,ZNF595,TAPT1,RCHY1,EPGN,NGDN,SNCAIP,BRI3BP,CEP135,FAM169A,DNM3,MPHOSPH8,EIF2AK2,DCAF8,IFT172,COG3,DMXL1,FBXL5,LOC439933,NUDT12,PTPRC,F11R,RABGAP1L,LINC01257,FAM129A,RB1,DTD2,RGS4,RGS12,LRPPRC,PACRGL,TXNDC15,MBNL2,ELK3,MARVELD2,DHRS2,TCTN2,ZNF671,ARSK,ETF1,PCGF3,F10,PCBD2,FCAR,TOMM40L,FNIP1,FGF9,PIBF1,FTLP10,VEZT,FBXO11,THADA,TADA1,CCDC88A,SLC12A2,PKD2L2,SLC15A4,C1orf112,SNRPF,KDM5B,NPAS3,MCCC2,NEDD1,IKBIP,COMMD6,INSM2,PPIP5K2,METAP2,GOLGA3,EML4,RNF17,TFDP1,CRB1,BAZ1A,ACTR6,TPO,ZNF550,HPCAL1,SLAIN1,HTR2A,ZNF470,ZNF84,PLB1,ZMYM2,ZBTB41,SLAMF9,LAD1,LINC00442,NUAK2,AXDND1" MicroRNA hsa-miR-148b:mirSVR_lowEffct hsa-miR-148b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.68E-44 1.42E-40 5.27E-42 4.83E-41 108 1835 "MDM4,BIRC6,ATP6V1G3,ANKRD34B,HOMEZ,APC,ZNF784,ARL1,AACS,ASTN1,CENPBD1P1,ATP12A,ZNF542P,ATP2B4,BCL2L2,NFATC4,CCNA1,AP1G2,NOVA1,SYT2,FCHO2,LDB2,UHMK1,SNTG2,RGSL1,PDE4D,PDGFRA,NRXN1,AKAP6,TAPT1,GNPTAB,HEATR5A,PREPL,DNM3,PRKD1,FCRL2,ZNF586,DCAF8,EPS8L1,PIGG,PTGS2,CEP350,G3BP2,GNPDA2,TSEN15,LAP3,RGS12,MEMO1,NTN4,LRPPRC,MBNL2,ELK3,MPHOSPH9,LGR6,DHRS2,STX2,DRAM1,EFS,ETF1,DLEU1,CLIP1,FCAR,NDUFAF7,SPON2,FGF9,RELL1,SUPT20H,RASA3,ZCCHC8,NBEA,GFM2,SLC30A6,IVNS1ABP,SLC8A1,ARHGEF40,CCDC88A,ZNF605,POTEM,SLC15A4,SLC22A5,MYO16,GABRB1,PDS5B,ERBIN,LPIN1,MAST4,ZNF544,ADAM17,PPIP5K2,TCF7,DOCK9,XPO4,FCRLA,RNF17,TFDP1,RAB2B,HSP90B1,UBE2K,GPN1,SLAIN1,ZNF876P,PAPPA2,IGF1,LHX9,FAM151B,DIAPH3,LINC00442,LMNB1" MicroRNA hsa-miR-219-2-3p:mirSVR_lowEffct hsa-miR-219-2-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-43 6.76E-40 2.41E-41 2.21E-40 107 1830 "MAP1B,BIRC6,KIAA1211,COG6,SEMA6A,RGS5,MCFD2,APBB2,WDR19,ARHGAP5,FAM193A,STXBP6,SLC4A4,ATP4B,KCTD12,MORN2,CD1E,PCDH9,DCLK1,ZMYM5,FAM177A1,CDK17,RGSL1,CHD1,ITGBL1,NRXN1,ADGRF3,GNPTAB,SYCP3,CEP135,KIAA0040,CTSG,EIF2AK2,PTPRC,OCIAD1,GNPDA2,SUPT7L,PARPBP,NR1H4,RB1,ARGLU1,SMC6,POLR1D,SETDB2,EIF2D,PACRGL,EFNA5,LATS2,MBNL2,EIF2B1,ELK3,STX2,CWC27,F7,USP44,GORAB,RELL1,POLK,SUCO,MROH9,FTLP10,SUPT20H,TM9SF1,NBEA,SLC8A1,TADA1,NR5A2,LIMCH1,GABRA2,PDS5B,IQGAP2,ATP8A2,NFASC,DRC1,MCCC2,STRN,UGT2A1,ADGRL3,ACSL6,TCF7,DOCK9,TFDP1,CRB1,BAZ1A,TNR,ATP6V0A2,TRPC4,HMGCR,GUF1,SLAIN1,PAPPA2,YTHDC2,IGF1,ZNF84,CCDC169,PLB1,CCDC190,ANKS1B,ZMYM2,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,CDK2AP1,LTA4H,ZNF304" MicroRNA hsa-miR-190:mirSVR_lowEffct hsa-miR-190:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-43 8.34E-40 2.88E-41 2.63E-40 103 1692 "SFTA3,MCC,BIRC6,NLN,ANKRD34B,WDR35,RGS5,FAM193A,KCTD12,RAB29,PNP,CDKL2,MPZL1,CAST,FCHO2,PCCA,DCLK1,PCSK1,PDE4D,PDGFRA,CFAP54,SNX6,NUP37,ADGRF3,LTB4R,THAP6,EPGN,SNCAIP,LACC1,ITSN2,FAM169A,UBXN2A,EIF2AK2,GLT8D2,MATR3,SPATA18,COG3,PTPRC,SACS,GNPDA2,MTX3,PARPBP,EGLN3,RGS12,MEMO1,MBNL2,TRAPPC12,SNORA49,KLHL12,ADGRV1,PCBD2,UTP15,N4BP2L2,ZCCHC8,G2E3,BRMS1L,NLRP2,MBIP,SLC8A1,THADA,TADA1,SF3B6,SLC22A4,UGGT2,CYP1B1-AS1,GABRA2,GABRB1,CIDEB,PDS5B,TMEM183A,UHRF1BP1L,ERAP1,HSPH1,NEDD1,LRCH1,IKBIP,MIMT1,ZBTB37,MAST4,ZNF544,UTP20,METAP2,ADGRL3,COX18,NT5C1B,MAEL,NPL,TECRL,TENT2,NLRP8,ZNF10,KCNT2,ZNF470,CCDC190,IRF1,ZBTB41,LMLN,KIF2A,KIT,TTC41P,RMST,AXDND1,ZNF304" MicroRNA hsa-miR-200b*:mirSVR_lowEffct hsa-miR-200b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-43 1.71E-39 5.69E-41 5.21E-40 104 1741 "BIRC6,ATP6V1G3,ANKRD34B,SEMA6A,APC,ARHGAP5,ASCL1,KCTD12,BCL2L2,PROZ,ARHGEF7,RAB29,PNP,CDKL2,NFXL1,SNTG2,SLC5A8,PCDH9,DCLK1,FAM177A1,PDGFRA,PDE6B,PIWIL1,CCDC122,WDFY2,JAKMIP1,STRN3,TOGARAM2,LYSMD3,CLOCK,SNCAIP,BRI3BP,IL20,CSNK1G3,VCAN,C12orf65,LRRTM2,DNM3,SREK1,CEP350,KLHL3,PTPRC,F11R,SUPT7L,LINC01257,RB1,SMC6,LAP3,TMEM33,CLIP4,SETDB2,EIF2B1,SNORA53,ELF1,GP6,ARSK,STK32B,CLIP1,ELOVL7,TRAPPC13,PCBD2,UTP15,TNFRSF19,FLT1,BRMS1L,SCYL2,CCDC88A,PKD2L2,TMEM132D,N4BP2,CHFR,UGGT2,MEGF10,MYT1L,KIF21B,NMNAT2,MRPS27,PCDH17,PPARGC1A,PPIP5K2,KMT5A,AP4S1,RASSF6,NPL,HEXB,GUF1,UGT2B7,SLAIN1,HTR2A,STARD4,SELENOI,IL6ST,ANKS1B,ZMYM2,ZBTB41,LHX9,TMEM178A,KCNN2,FIP1L1,KIF3C,DNAH10,LMNB1,SKA3,MICU2" MicroRNA hsa-miR-190b:mirSVR_lowEffct hsa-miR-190b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.82E-43 2.03E-39 6.55E-41 5.99E-40 101 1639 "SFTA3,MCC,BIRC6,NLN,ANKRD34B,WDR35,RGS5,DDX55,FAM193A,RAB29,PNP,CDKL2,MPZL1,CAST,FCHO2,PCCA,DCLK1,PCSK1,PDE4D,PDGFRA,CFAP54,LINC01085,SNX6,NUP37,ADGRF3,LTB4R,THAP6,HOMER1,EPGN,SNCAIP,LACC1,ITSN2,FAM169A,UBXN2A,EIF2AK2,GLT8D2,MATR3,SPATA18,COG3,TBC1D4,PTPRC,SACS,GNPDA2,MTX3,PARPBP,EGLN3,RGS12,MEMO1,MBNL2,TRAPPC12,SNORA49,ARSK,ETF1,ADGRV1,PCBD2,UTP15,N4BP2L2,ZCCHC8,G2E3,BRMS1L,NLRP2,MBIP,PAICS,SLC8A1,THADA,TADA1,SF3B6,SLC22A4,UGGT2,GABRA2,GABRB1,CIDEB,TMEM183A,UHRF1BP1L,ERAP1,NEDD1,LRCH1,MIMT1,ZBTB37,MAST4,ZNF544,UTP20,ADGRL3,NT5C1B,MAEL,NPL,TECRL,TENT2,NLRP8,ZNF10,KCNT2,ZNF470,CCDC190,IRF1,ZBTB41,LMLN,KIT,TTC41P,RMST,AXDND1,ZNF304" MicroRNA hsa-miR-3074:mirSVR_lowEffct hsa-miR-3074:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.77E-43 3.07E-39 9.58E-41 8.77E-40 108 1897 "SFTA3,MAP1B,TBC1D14,WDR35,CUL4A,EP400,APAF1,APC,FAM193A,STARD13,CD84,BTF3,NOVA1,MPZL1,CAST,FCHO2,CHAMP1,LDB2,CD1E,NFXL1,FCRLB,SNTG2,PCDH9,PDGFRA,CCDC122,GPR180,LYSMD3,SNCAIP,DNM3,EIF2AK2,FCRL2,MATR3,BIVM,SREK1,DCT,KLHL3,PTPRC,PARPBP,PPP2R3C,RASA1,ARGLU1,SMC6,TMEM33,RNASEL,LATS2,SNORA53,KIRREL1,ELK3,MARVELD2,STK32B,ETF1,ABCA11P,ELOVL7,FNIP1,N4BP2L2,POLK,FLT1,FLT3,NBEA,BRMS1L,ALKAL2,MBIP,UFM1,GFM2,IVNS1ABP,CCDC88A,SLC12A2,PKD2L2,WDCP,SLC22A4,CHFR,LIMCH1,MYO16,TMEM183A,UHRF1BP1L,HSPH1,CMPK2,IKBIP,GJA3,TMED2,ATP11A,ADGRL3,LILRB4,ANO4,RNF17,CRB1,SLC7A8,RASSF6,FZD10,HEXB,ADAMTS19,UBE2K,TECRL,TENT2,HTR2A,NSD2,ZNF10,IGF1,KCNT2,SPTSSA,CCDC190,TMEM178A,LMLN,FIP1L1,TTC41P,LINC01913,LOX,ZNF304" MicroRNA hsa-miR-935:mirSVR_lowEffct hsa-miR-935:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.60E-43 4.04E-39 1.23E-40 1.12E-39 102 1687 "MATN3,MCC,NLN,COG6,WDR35,CUL4A,PITPNM2,BLZF1,ASTN1,ATP2B4,CAST,ODC1,FCHO2,NFXL1,CDK17,PDGFRA,PFKFB2,LINC01085,POLN,PTPRVP,THAP6,AKAP6,STRN3,EPGN,LACC1,VCAN,DNM3,DDX59,MATR3,BIVM,DGKQ,COG3,LOC439933,CEP350,COCH,CEP120,F11R,PPP2R3C,B3GLCT,SMC6,SLC9C2,MEMO1,LRPPRC,ELK3,MPHOSPH9,FAM172A,ARSK,ETF1,TLR6,CLIP1,TOMM40L,PIBF1,SUCO,PEAR1,FLT1,STAB2,SUPT20H,ZCCHC8,NBEA,MBIP,SLC15A4,TNFSF13B,GABRA2,PDS5B,CD244,NPAS3,CMPK2,MCCC2,LRCH1,COMMD6,GJA3,GJB2,ADAM17,MTUS2,CNTN2,ADGRL3,LILRB4,DOCK9,C1QTNF9B,CRB1,BAZ1A,ADAMTS19,UBE2K,SLAIN1,POC5,TENT2,NSD2,ZNF26,ZNF84,ANKS1B,ZMYM2,ZBTB41,TMEM178A,KIT,RNASE11,LINC00442,ZDHHC20,LMNB1,CDK2AP1,IFT88,LOX,ZNF304" MicroRNA hsa-miR-548k:mirSVR_highEffct hsa-miR-548k:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.44E-43 4.49E-39 1.32E-40 1.21E-39 102 1689 "RALGAPA1,CUL4A,WDR19,ARL1,CCDC181,ARHGEF7,NFKBIA,ADGRD1,NOVA1,CAMK4,UHMK1,NFXL1,CDK17,CFL2,RCBTB2,CHD1,NRXN1,BOD1L1,STRN3,COPA,GNPTAB,LYSMD3,CRHBP,CSNK1G3,VCAN,CEP135,ZNF586,MATR3,BIVM,SREK1,COG3,PTGS2,DMXL1,NUDT12,COCH,CEP120,SACS,G3BP2,WDR1,PPP2R3C,C14orf119,SLC9C2,CLIP4,LATS2,MBNL2,DCUN1D2,CWC27,MAEA,ETF1,FCGR3A,FGF9,RELL1,POLK,FLT1,NBEA,MBIP,SLC30A6,IVNS1ABP,THADA,TADA1,CCDC88A,YPEL5,GABRA2,MYT1L,PDS5B,RAPGEF6,NAAA,UHRF1BP1L,ERAP1,HSPH1,NPAS3,MRPS27,MCCC2,IKBIP,ZBTB37,TMED2,ADGRL3,ADGRA3,GPR12,KMT5A,DOCK9,NCSTN,FCRLA,RNF17,NT5C1B,CRB1,TGFBI,AP4S1,TMPO,MAEL,ATP6V0A2,GPN1,GUF1,PAPPA2,STARD4,YTHDC2,ZNF26,SPTSSA,CHPT1,DIAPH3,DNAH10,IFT88" MicroRNA hsa-miR-1283:mirSVR_highEffct hsa-miR-1283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-42 7.30E-39 2.09E-40 1.91E-39 108 1915 "RALGAPA1,MATN3,ADD1,COG6,NYNRIN,WDR35,UVSSA,ARL1,STXBP6,ZNF542P,ATP7B,NFKBIA,NOVA1,CAST,ODC1,FCHO2,UHMK1,ZMYM5,PDE4D,CENPC,CFL2,CHD1,PFKFB2,ZNF595,GPR180,NRXN1,PIGR,ATAD2B,HECTD1,AKAP6,RCHY1,PREPL,CRHBP,SNCAIP,UBXN2A,MPHOSPH8,FCRL2,ZFYVE16,MATR3,BIVM,DMXL1,PTPRC,OCIAD1,SACS,RABGAP1L,TSEN15,RNF219,ATG10,RB1,MBNL2,ELF1,MPHOSPH9,MARVELD2,TCTN2,ARSK,MAEA,ETF1,ABCA11P,PCBD2,FNIP1,FGF9,MROH9,FBXO11,BRMS1L,PAICS,SLC30A6,ARHGEF40,SLC12A2,N4BP2,MYO16,MEGF10,GABRB1,RAPGEF6,GJB6,NPAS3,KDM3B,LRCH1,MIMT1,SULT1E1,PPARGC1A,GJB2,UTP20,PPIP5K2,ADGRL3,STON1,KMT5A,NT5C1B,TFDP1,ZBTB49,TMPO,ZNF721,HSP90B1,TRPC4,HMGCR,ZNF550,SLAIN1,ZNF876P,TENT2,STARD4,NSD2,ZNF26,KCNT2,CENPH,ZMYM2,FIP1L1,KIF2A,RMST,CDK2AP1" MicroRNA hsa-miR-382:mirSVR_lowEffct hsa-miR-382:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-42 9.03E-39 2.47E-40 2.26E-39 103 1738 "LRRC43,MDM4,NDRG2,BIRC6,SLAMF6,ANKRD34B,COG6,WDR35,APC,DDX55,BLZF1,ARHGAP5,ASCL1,FCRL3,CCNA1,CBLN3,MORN2,CD1D,SNTG2,ZMYM5,XPR1,PDE4D,PGGT1B,GPR180,NRXN1,BOD1L1,RCHY1,TOGARAM2,FAM169A,DNM3,UBXN2A,MATR3,EPS8L1,PIGG,NUDT12,FAM129A,B3GLCT,RB1,CLIP4,MEMO1,RNF4,EIF2B1,SNORA53,ELF1,BORA,DRAM1,CWC27,DNAJC27,TOMM40L,TNFRSF19,RELL1,TACC3,FBXO11,DDX51,SCYL2,CCDC88A,PKD2L2,SLC15A4,SLC22A5,SNRPF,MEGF10,GABRA2,PDS5B,KDM5B,FAM114A1,CENPJ,NAAA,TMEM183A,MRPS27,LRCH1,ERBIN,CFHR4,ZBTB37,GJA3,DHRS4,BRD8,TBC1D1,COX7B2,PPIP5K2,METAP2,ADGRL3,GPR18,ARHGEF28,RNF17,GRSF1,MAEL,ATP6V0A2,NPL,RXFP2,VRK2,WDR36,FCRL6,ZNF324B,IL6ST,PLB1,LMLN,KIF3C,KIR3DL2,AMTN,TTC41P,DNAH10,TTC7A,LOX" MicroRNA hsa-miR-30d:mirSVR_highEffct hsa-miR-30d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.72E-42 9.13E-39 2.47E-40 2.26E-39 104 1774 "RALGAPA1,SMIM15,BIRC6,ADD1,KIAA1211,NLN,PITPNM2,WDR19,BCL2L2,BTF3,CCNA1,CAMK4,FCHO2,PCDH9,PDE4D,CFL2,CHD1,DHRS1,GPR180,SMIM14,SNX6,ATAD2B,BOD1L1,LTB4R,HOMER1,AKAP6,RCHY1,CLOCK,CSNK1G3,LRRTM2,CEP135,MATR3,DHX9,CEP350,NUDT12,SACS,RABGAP1L,WDR1,TSEN15,DNMT3A,RASA1,DTD2,CLIP4,POLR1D,TXNDC15,MBNL2,UGT2A3,ELF1,STX2,DEPDC4,FAM81B,ABCA11P,PCGF3,ELOVL7,SH3YL1,TRAPPC13,FCGR2B,GORAB,RELL1,FOXG1,MROH9,SUPT20H,RUBCNL,FBXO11,UFM1,C1orf112,SLC22A5,NR5A2,YPEL5,LIMCH1,CYP1B1-AS1,MYO16,GABRB1,JPH4,TMEM183A,ERAP1,ATP8A2,NPAS3,IKBIP,KLHL20,PCDH17,PPARGC1A,MAST4,TBC1D1,PPIP5K2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,CRB1,GUF1,TENT2,IL25,ZMYM2,FAM49A,LMLN,FIP1L1,LCP1,RMST,AXDND1,LOX" MicroRNA hsa-miR-595:mirSVR_lowEffct hsa-miR-595:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-42 1.12E-38 2.94E-40 2.69E-39 104 1778 "MATN3,BIRC6,WDR35,APAF1,APC,WDR19,ARHGAP5,STXBP6,ZNF542P,FGFRL1,CD84,CACNA1E,CAMK4,PCK2,CDK18,CHD1,ZNF595,PGGT1B,WDFY2,CKMT2,SNX6,BOD1L1,HECTD1,AKAP6,FAM163A,COPA,EPGN,CLOCK,ITSN2,KIAA0040,UBXN2A,FCRL5,FCRL2,ZFYVE16,SPATA18,SREK1,PTGS2,COCH,DHFR,SUPT7L,PPP2R3C,FAM129A,SMC6,DTD2,RGS4,NTN4,EIF2D,UGT2A3,MPHOSPH9,ETF1,PCGF3,CLIP1,FCAR,TOMM40L,PIBF1,FOXO1,FLT1,VEZT,FBXO11,DDX51,BRMS1L,SLC8A1,CGREF1,N4BP2,EFR3B,DCAF11,MEGF10,MYT1L,KDM5B,NAAA,IQGAP2,GJB6,NPAS3,SRP54,NFASC,LRCH1,GJA3,MAST4,COX7B2,PPIP5K2,METAP2,DOCK9,TFDP1,CRB1,ZBTB49,HEXB,ADAMTS19,HSD17B4,C12orf73,PLB1,ZNF140,LINC00272,PGAM5,NPHS2,ZBED3-AS1,CHPT1,KCNJ9,DIAPH3,KIR3DL2,KIT,RNASE11,LCP1,NUAK2,LOX" MicroRNA hsa-miR-181a-2*:mirSVR_lowEffct hsa-miR-181a-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-42 1.29E-38 3.31E-40 3.03E-39 105 1817 "MAP1B,MCC,ADD1,ACOX3,TBC1D14,MSH2,ASCL1,NCOA1,CCDC181,CD84,NFATC4,RAB29,PCDH9,DCLK1,XPR1,CDK17,PDGFRA,PFKFB2,VIT,WDFY2,SLC25A3,ATAD2B,BOD1L1,HOMER1,CEP135,KIAA0040,UBXN2A,PRKD1,FCRL5,MATR3,KLHL3,CEP120,PTPRC,SACS,GNPDA2,WDR1,NR1H4,ZNF329,SLC9C2,RGS12,PACRGL,EFNA5,LATS2,KIRREL1,ELK3,LGR6,EFS,ARSK,DLEU1,ABCA11P,ADGRV1,PCGF3,CLIP1,F10,ELOVL7,FCGR3A,FCGR3B,PIBF1,FOXO1,VEZT,TM9SF1,DDX51,BRMS1L,SLC8A1,THADA,TADA1,SLC12A2,POTEM,TMEM132D,CGREF1,SLC22A5,EFR3B,UGGT2,KIF21B,ZNF274,ATP8A2,CMPK2,MCCC2,NEDD1,LRCH1,KLHL20,STRN,TMED2,LINC02393,ATP11A,METAP2,GOLGA3,ADGRL3,ADGRA3,TDG,TFDP1,CRB1,SLC7A8,ZBTB49,RIMBP2,UBE2K,TENT2,ZNF470,C12orf73,ZBTB41,KIR2DL4,KIT,LINC01913,LETM1,RMST" MicroRNA hsa-miR-3120:mirSVR_highEffct hsa-miR-3120:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.06E-42 1.63E-38 4.07E-40 3.73E-39 109 1969 "RALGAPA1,COG6,TBC1D14,HOMEZ,APC,WDR19,KCTD12,ARHGEF7,NOVA1,AMDHD1,RILPL1,FCHO2,LDB2,FCGR2C,FCRLB,PCDH9,SCFD2,PFKFB2,GPR180,NUP37,ATAD2B,HECTD1,HOMER1,AKAP6,MPC2,TAPT1,CSNK1G3,FAM169A,DNM3,PIGG,COG3,PTGS2,DMXL1,NUDT12,OCIAD1,SACS,G3BP2,SLC35F6,PPP2R3C,NR1I3,NR1H4,DNMT3A,B3GLCT,RASA1,ARGLU1,AASDH,DTD2,CLIP4,ZNF419,UGT2A3,DHRS2,GP6,FAM172A,DEPDC4,ARSK,ETF1,ELOVL7,FNIP1,N4BP2L2,FGFR3,RELL1,POLK,FLT1,FMO1,FBXO11,NBEA,BRMS1L,UFM1,THADA,TADA1,CCDC88A,SLC15A4,SLC22A5,YPEL5,UGGT2,GABRA2,MYT1L,NAAA,TMEM183A,CMPK2,SRP54,RBKS,ERBIN,TBC1D1,COX7B2,ADGRL3,ANO4,STON1,RNF212,TDG,RNF17,GRSF1,RAB2B,TMPO,ATP6V0A2,UBE2K,PAPPA2,HTR2A,ZNF10,CENPH,TADA2B,SPTSSA,ZMYM2,LHX9,ZBED3-AS1,TMEM178A,RNASE11,RMST,MICU2" MicroRNA hsa-miR-496:mirSVR_lowEffct hsa-miR-496:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.33E-42 2.84E-38 6.92E-40 6.33E-39 99 1619 "RALGAPA1,MAP1B,BIRC6,ADD1,NLN,ARHGAP5,ARL1,ASCL1,CCDC181,ATP2B4,KCTD12,GAS2L3,CAST,PCCA,ZMYM5,SCFD2,PDE4D,CENPC,GPR180,SMIM14,ATAD2B,BOD1L1,HECTD1,PTPRVP,C1orf116,RCHY1,HEATR5A,NCOR2,LACC1,ITSN2,CEP135,FAM169A,DNM3,KIAA0040,ZFYVE16,MATR3,SNX17,MTX3,DHFR,PARPBP,RNF219,NR1I3,TMEM161B,AASDH,FAM228A,RGS4,LAP3,POLR1D,SETDB2,EFNA5,MBNL2,DHRS2,TBC1D19,SAP18,ETF1,ELOVL7,TRAPPC13,TOMM40L,POLK,RASA3,ZCCHC8,IVNS1ABP,THADA,ARHGEF40,TADA1,CCDC88A,N4BP2,SF3B6,FSHR,CHFR,MEGF10,EAPP,ERAP1,ATP8A2,NPAS3,KDM3B,PPARGC1A,KHNYN,RNF17,SLC7A8,TMPO,TMEM174,SLAIN1,ZNF876P,WDR36,NSD2,JCHAIN,IL6ST,CCDC169,ZBTB41,TDRD3,FAM49A,DNAH10,LCP1,LINC00442,NUAK2,AXDND1,ZDHHC20,IFT88" MicroRNA hsa-miR-380:mirSVR_highEffct hsa-miR-380:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.98E-42 3.18E-38 7.57E-40 6.93E-39 108 1946 "MAP1B,SMIM15,BIRC6,KIAA1211,NLN,CUL4A,RGS5,UVSSA,APAF1,APC,ARHGAP5,NOP14,ASTN1,ATP1A2,SLC4A4,STARD13,KCTD12,DAOA,CBLN3,CDKL2,TAF1B,PDE4D,CFL2,PIWIL1,RCBTB2,ITGBL1,NRXN1,AKAP6,COPA,HEATR5A,LYSMD3,SNCAIP,CSNK1G3,DNM3,UBXN2A,FCRL5,GLT8D2,ZNF586,DCAF8,ZFYVE16,COG3,FBXL5,LOC439933,NUDT12,PTPRC,OCIAD1,RABGAP1L,NR1H4,SMC6,AASDH,POLR1D,MBNL2,DCUN1D2,KLHL12,CWC27,ADGRV1,ELOVL7,PCBD2,UTP15,GORAB,FNIP1,FGF9,FGFR3,POLK,SUCO,HSD17B7,G2E3,SLC8A1,CCDC88A,SLC12A2,GABRA2,ZNF274,UHRF1BP1L,HSPH1,KDM3B,CMPK2,SRP72,NEDD1,ERBIN,UGT2A1,PPIP5K2,METAP2,ADGRL3,ADGRA3,STON1,DOCK9,YIPF7,TDG,TEP1,LINC01551,HAL,HEXB,ADAMTS19,UBE2K,HMGCR,SLAIN1,TENT2,KCNT2,ZNF140,IRF1,FAM151B,KIF2A,DIAPH3,TTC41P,SPRYD7,AXDND1,LIG4,LOX" MicroRNA hsa-miR-659:mirSVR_lowEffct hsa-miR-659:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-41 5.39E-38 1.25E-39 1.15E-38 106 1883 "BIRC6,TMEM132B,NLN,WDR35,SNX24,ARHGAP5,ATP4B,BTF3,FCHO2,CHAMP1,CD1D,PCDH9,ZMYM5,CDK18,CENPC,CHIT1,SNX6,HOMER1,AKAP6,FAM163A,THTPA,CRHBP,SNCAIP,LACC1,VCAN,LRRTM2,DNM3,GLT8D2,MATR3,PTGS2,NUDT12,DHFR,C12orf42,PXMP2,LINC01257,PARPBP,RASA1,RB1,AASDH,RNASEL,KIRREL1,LGR6,MARVELD2,BORA,STX2,FCGR3B,NDUFAF7,PIBF1,POLK,SUCO,PEAR1,MROH9,FOXO1,FLT1,FTLP10,ZCCHC8,FBXO11,UFM1,CCDC88A,SLC12A2,C1orf112,SLC22A4,UGGT2,MEGF10,GABRA2,RAPGEF6,NAAA,TMEM183A,ERAP1,OXGR1,IKBIP,MAST4,TMED2,COX7B2,KHNYN,RNF17,TEP1,CRB1,SLC7A8,TGFBI,GPR161,AP4S1,RASSF6,TNR,ADAMTS19,TECRL,GUF1,SLAIN1,VRK2,HTR2A,WDR36,DCP2,ZFHX2,IL6ST,CCDC169,SPTSSA,ANKS1B,LHX9,FAM151B,ZBED3-AS1,KIR2DL4,KIR2DS4,LAD1,LCP1,SPRYD7,AXDND1" MicroRNA hsa-miR-194:mirSVR_lowEffct hsa-miR-194:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-41 7.15E-38 1.62E-39 1.49E-38 107 1926 "MAP1B,TBC1D14,WDR35,HOMEZ,ADCY4,BLZF1,ARHGAP5,SLC4A4,NLRP4,CCNA1,LINC02347,NOVA1,CAST,CHAMP1,NFXL1,XPR1,CDK18,JAKMIP1,ADGRF3,THAP6,C1orf116,TAPT1,CLOCK,CRHBP,LACC1,CSNK1G3,FAM169A,DNM3,PRKD1,BIVM,PIGG,CEP350,NUDT12,TBC1D4,SACS,RABGAP1L,GNPDA2,PARPBP,PPP2R3C,RNF219,DNMT3A,RAN,FAM129A,RB1,CLIP4,SETDB2,LATS2,RNF4,TRAPPC12,MARVELD2,FAM172A,DRAM1,SAP18,MAEA,FCGR2B,FGFR3,RELL1,FTLP10,SUPT20H,DDX51,ALKAL2,NLRP2,MBIP,UFM1,SLC8A1,ARHGEF40,CPSF3,GABRA2,KIF21B,KDM5B,NAAA,HSPH1,NPAS3,RBKS,MCCC2,NEDD1,IKBIP,PPARGC1A,GJA3,PSME4,TMED2,ADAM17,ADGRA3,STON1,EML4,KHNYN,COX18,RNF17,TEP1,NT5C1B,TFDP1,MAEL,ATP6V0A2,UBE2K,TRPC4,TXK,SLAIN1,PAPPA2,NSD2,IGF1,KCNT2,PLB1,LHX9,ZBED3-AS1,LCP1,SPRYD7,LMNB1" MicroRNA hsa-miR-374a*:mirSVR_highEffct hsa-miR-374a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-41 9.15E-38 2.03E-39 1.86E-38 96 1537 "MATN3,MCC,MDM4,BIRC6,NLN,ATP6V1G3,WDR35,SEMA6A,APC,BLZF1,CENPBD1P1,FCRL3,BTF3,NOVA1,LDB2,PAH,SNTG2,CDK17,PDE4D,PDGFRA,CFL2,CHD1,GPR180,HOMER1,GNPTAB,EPGN,LYSMD3,CLOCK,PREPL,SNCAIP,CSNK1G3,UBXN2A,ZFYVE16,SREK1,COCH,CEP120,MTX3,DHFR,PARPBP,PPP2R3C,EGLN3,ARGLU1,RNF4,MBNL2,DCUN1D2,UGT2A3,MARVELD2,TBC1D19,FAM172A,DRAM1,ARSK,ADGRV1,TRAPPC13,NDUFAF7,FLT1,VEZT,GFM2,TADA1,CCDC88A,N4BP2,YPEL5,CHFR,MYO16,GABRA2,GABRB1,PDS5B,TMEM183A,IQGAP2,CMPK2,LRCH1,IKBIP,PPARGC1A,UGT2A1,PPIP5K2,LILRB4,GPR18,YIPF7,TDG,MSH6,BAZ1A,TMPO,MAEL,ATP6V0A2,UBE2K,HMGCR,TECRL,STARD4,YTHDC2,ZNF470,ZNF140,ANKS1B,ZMYM2,CAB39L,LAD1,RMST,AXDND1" MicroRNA hsa-miR-548u:mirSVR_highEffct hsa-miR-548u:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-41 9.57E-38 2.08E-39 1.91E-38 102 1749 "MAP1B,IL17D,KIAA1211,HOMEZ,UVSSA,WDR19,ARL1,FAM193A,SLC4A4,PPP1R12B,BTF3,CACNA1E,CBLN3,AMDHD1,CHAMP1,PCCA,FAM177A1,PCSK1,CDK17,PDGFRA,CHD1,STRN3,TAPT1,PM20D1,POU2F1,SYCP3,LYSMD3,PREPL,NGDN,CSNK1G3,NOS1AP,ZNF586,ZFYVE16,BIVM,PIGG,SREK1,COG3,DCT,PTGS2,SACS,G3BP2,RABGAP1L,SUPT7L,PPP2R3C,ATG10,RB1,PACRGL,MBNL2,KLHL12,ARSK,DLEU1,CLIP1,SLC22A17,ELOVL7,USP44,TOMM40L,GORAB,POLK,SDC1,FMO1,FBXO11,UFM1,CCDC88A,PKD2L2,N4BP2,WDCP,C1orf112,SLC22A5,ZNF667,PDS5B,NAAA,ERAP1,HSPH1,NPAS3,RBKS,ERBIN,IKBIP,KLHL20,NPFFR2,PPARGC1A,BRD8,MAST4,PSME4,ACSL6,TCF7,DOCK9,TFDP1,ZBTB49,POC5,TENT2,HTR2A,WDR36,IL25,KCNT2,ZFHX2,ZMYM2,FIP1L1,DIAPH3,TTC41P,AXDND1,LMNB1,IFT88" MicroRNA hsa-miR-556-3p:mirSVR_lowEffct hsa-miR-556-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.81E-41 2.02E-37 4.31E-39 3.94E-38 104 1837 "LRRC43,ANKRD34B,COG6,WDR35,RGS5,APBB2,APC,CDKL4,NOP14,FAM193A,NCOA1,CADM3,BCL2L2,CCNA1,NOVA1,CDKL2,CAMK4,LDB2,SCARB1,CFL2,CHD1,SMIM14,PKP1,HOMER1,AKAP6,MPC2,POU2F1,SYCP3,EPGN,CLOCK,SNCAIP,LACC1,IL20,C12orf65,DMXL1,NUDT12,SACS,RABGAP1L,GNPDA2,PARPBP,PPP2R3C,EGLN3,ATG10,RB1,CLIP4,NTN4,TXNDC15,TBC1D19,FAM172A,CWC27,DNAJC27,ABCA11P,ADGRV1,TRAPPC13,FGF9,SDC1,MROH9,HSD17B7,ZCCHC8,FBXO11,G2E3,NBEA,BRMS1L,ALKAL2,SCYL2,CCDC88A,ZNF605,SLC12A2,TMEM132D,NR5A2,YPEL5,MEGF10,GABRA2,PDS5B,NAAA,ZNF274,OXGR1,SRP72,LRCH1,GJB2,PSME4,UGT2A1,ATP11A,ACSL6,TDG,RNF17,GRSF1,CRB1,SLC7A8,TGFBI,ZNF721,HAL,TXK,VRK2,YTHDC2,JCHAIN,ZNF470,ANKS1B,FAM49A,FIP1L1,EP400P1,LINC01913,LMNB1,CDK2AP1" MicroRNA hsa-miR-3156:mirSVR_lowEffct hsa-miR-3156:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.64E-41 3.00E-37 6.25E-39 5.73E-38 98 1629 "MAP1B,MDM4,BIRC6,WDR35,UVSSA,DDX55,ARHGAP5,FAM193A,STXBP6,ZNF542P,KCTD12,AP1G2,LINC02347,RAB29,NOVA1,TAF1B,RILPL1,NFXL1,SLC5A8,ZNF664,PCDH9,PCSK1,C1orf116,AKAP6,RCHY1,GNPTAB,CSNK1G3,DNM3,NOS1AP,DCAF8,BIVM,SREK1,COG3,PTGS2,FBXL5,KLHL3,CEP120,PTPRC,PTPRH,TSEN15,RASA1,RB1,OGFOD2,AASDH,REST,RGS12,TRAPPC12,ELK3,DLEU1,DNAJC27,ADGRV1,CLIP1,PCBD2,FCGR3B,FGF9,RELL1,FMO1,GOLGA2P5,BRMS1L,UFM1,SLC8A1,THADA,C1orf112,DCAF11,GABRA2,ERAP1,ATP8A2,CMPK2,NFASC,IKBIP,GJA3,MAST4,ATP11A,MTUS2,ARHGEF28,COX18,CRB1,ACTR6,ARHGAP30,GUF1,HSD17B4,ZNF876P,PAPPA2,WDR36,NSD2,IGF1,MZF1,IL6ST,ZBTB41,LHX9,FAM151B,KCNJ9,DIAPH3,DNAH10,LINC01913,LINC00442,NUAK2,IFT88" MicroRNA hsa-miR-376a*:mirSVR_lowEffct hsa-miR-376a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-40 6.65E-37 1.36E-38 1.24E-37 101 1752 "RALGAPA1,ABL2,MATN3,ATP6V1G3,NYNRIN,WDR35,PITPNM2,MCFD2,FBRSL1,ASCL1,ATP1A2,ATP2B4,KCTD12,PPP1R12B,BCL2L2,FCRL3,BTF3,MPZL1,TSSK4,PCDH9,ZMYM5,XPR1,PDGFRA,SLC25A3,CFAP54,THAP6,C1orf116,TAPT1,POU2F1,VCAN,FAM169A,UBXN2A,FCRL2,ZFYVE16,SPATA18,FBXL5,NUDT12,COCH,CEP120,RABGAP1L,ATG10,RB1,AASDH,LAP3,CLIP4,POLR1D,PACRGL,MBNL2,MPHOSPH9,CWC27,ADGRV1,TRAPPC13,TMEM156,N4BP2L2,PIBF1,FLT3,ZCCHC8,G2E3,NBEA,ALKAL2,CCDC88A,PKD2L2,LIMCH1,NAAA,CD244,UHRF1BP1L,HSPH1,NPAS3,CMPK2,NEDD1,LRCH1,ERBIN,IKBIP,GJA3,BRD8,UGT2A1,ADAM17,PPIP5K2,ARHGEF28,TEP1,TFDP1,CRB1,RASSF6,ACTR6,HMGCR,TECRL,NLRP8,HTR2A,TPTE2,DCP2,ZNF10,ZNF84,IL6ST,LHX9,CHPT1,KCNJ9,AMTN,RPGRIP1,TTC41P,LAD1,LCP1" MicroRNA hsa-miR-135a:mirSVR_highEffct hsa-miR-135a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.34E-40 7.12E-37 1.42E-38 1.30E-37 92 1438 "MDM4,SNX24,APC,ATP1A2,CADM3,FCRL3,ARHGEF7,CAMK4,FCHO2,LDB2,PCCA,PCDH9,CDK17,PGGT1B,GPR180,ITGBL1,LINC01085,SNX6,PMCH,STRN3,COPA,HEATR5A,EPGN,PREPL,CSNK1G3,VCAN,CEP135,UBXN2A,PRKD1,DMXL1,LOC439933,TBC1D4,LINC01257,B3GLCT,RNF31,RASA1,CLIP4,POLR1D,LATS2,SNORA49,ELK3,EFS,TMEM156,POLK,FOXO1,HSD17B7,FTLP10,STAB2,VEZT,NBEA,NUBPL,UFM1,SLC8A1,TADA1,CCDC88A,ZNF605,C1orf112,ZNF667,GABRA2,PDS5B,NAAA,CD244,ERAP1,DRC1,NEDD1,PPARGC1A,BRD8,MAST4,MTUS2,CNTN2,ANO4,FCRLA,RNF17,NT5C1B,CRB1,RASSF6,NPL,GPN1,LTB4R2,YTHDC2,IL6ST,ZNF140,LHX9,FAM151B,CAB39L,DIAPH3,TTC41P,LINC01913,LCP1,RMST,IFT88,LOX" MicroRNA hsa-miR-508-5p:mirSVR_lowEffct hsa-miR-508-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-40 9.73E-37 1.91E-38 1.75E-37 104 1870 "MATN3,SMIM15,BIRC6,ADORA1,SLAMF6,TBC1D14,CUL4A,EP400,SNX24,DDX55,BLZF1,AACS,ATP4B,B4GALT3,CADM3,NFATC4,LINC02347,PNP,CBLN3,CCNB1,CD1D,UHMK1,PDGFRA,RCBTB2,JAKMIP1,POLN,STRN3,EPGN,GALNT9,FAM169A,PRKD1,FCRL2,CEP350,TBC1D4,PTPRH,SACS,RABGAP1L,GNPDA2,DHFR,PARPBP,TSEN15,NR1I3,RGS4,GUSBP3,RNASEL,EIF2B1,MARVELD2,FCAMR,STX2,FAM172A,FAM81B,ABCA11P,ADGRV1,PCGF3,USP44,PCBD2,FCAR,SELP,FLT1,RASA3,NBEA,UFM1,STPG4,IVNS1ABP,THADA,ARHGEF40,ZNF605,SLC12A2,PKD2L2,POTEM,C1orf112,RAPGEF6,ATP8A2,HSPH1,OXGR1,NPAS3,KDM3B,CMPK2,SRP72,IKBIP,PPARGC1A,DHRS4,PSME4,ZNF544,INSM2,ADGRL3,ARHGEF28,RNF212,RNF17,AP4S1,GTF2H3,MAEL,NLRP8,ZNF10,TADA2B,IL6ST,ANKS1B,ZBED3-AS1,CHPT1,KIT,NUAK2,LMNB1,SKA3,SPATA13" MicroRNA hsa-miR-567:mirSVR_lowEffct hsa-miR-567:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-40 1.55E-36 2.95E-38 2.70E-37 100 1733 "MATN3,MCC,SMIM15,IL17D,BIRC6,NLN,EP400,ARL1,NOP14,FAM193A,NCOA1,SLC4A4,ATP4B,FGFRL1,FCHO2,CD1E,XPR1,CDK7,PFKFB2,CCDC122,NUP37,HECTD1,THAP6,HOMER1,POU2F1,CLOCK,CEP135,DNM3,PRKD1,FCRL5,PIGG,COG3,DMXL1,CEP350,PTPRC,PTPRH,GNPDA2,SUPT7L,C14orf119,TMEM161B,SMC6,NTN4,TRAPPC12,ELF1,ZNF671,DRAM1,ARSK,ETF1,ABCA11P,UTP15,G2E3,BRMS1L,ALKAL2,ZNF446,SCYL2,THADA,PKD2L2,P2RX2,ZNF667,YPEL5,LIMCH1,GABRB1,JPH4,TMEM183A,ERAP1,NPAS3,SRP72,MCCC2,NEDD1,LRCH1,GJA3,MAST4,METAP2,GOLGA3,ANO4,ACSL6,ARHGEF28,RNF212,COX18,RNF17,TFDP1,ATP6V0A2,UBE2K,TRPC4,TECRL,GUF1,ZNF876P,VRK2,NSD2,FCRL6,ZNF10,ZFHX2,ZNF84,PLB1,ZMYM2,ZBTB41,AMTN,EP400P1,FAM71C,IFT88" MicroRNA hsa-miR-148a:mirSVR_lowEffct hsa-miR-148a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.94E-40 1.57E-36 2.95E-38 2.70E-37 103 1843 "MDM4,BIRC6,ATP6V1G3,ANKRD34B,HOMEZ,ZNF784,ARL1,AACS,ASTN1,CENPBD1P1,ATP12A,ZNF542P,ATP2B4,BCL2L2,NFATC4,CCNA1,AP1G2,NOVA1,SYT2,RILPL1,FCHO2,LDB2,UHMK1,SNTG2,PDE4D,PDGFRA,NRXN1,THAP6,TAPT1,GNPTAB,HEATR5A,DNM3,PRKD1,FCRL2,DCAF8,EPS8L1,PIGG,PTGS2,CEP350,G3BP2,GNPDA2,SUPT7L,RB1,LAP3,MEMO1,NTN4,LRPPRC,ELK3,MPHOSPH9,STX2,EFS,SAP18,ETF1,CLIP1,FCAR,NDUFAF7,SPON2,FGF9,RELL1,PIBF1,SUPT20H,RASA3,ZCCHC8,NBEA,GFM2,SLC30A6,IVNS1ABP,SLC8A1,ARHGEF40,CCDC88A,ZNF605,SLC12A2,POTEM,SLC15A4,C1orf112,SLC22A5,MYO16,GABRB1,ERBIN,MAST4,ZNF544,ADAM17,TCF7,DOCK9,XPO4,FCRLA,RNF17,GRSF1,TFDP1,RAB2B,HSP90B1,UBE2K,GPN1,SLAIN1,ZNF876P,PAPPA2,IGF1,LHX9,FAM151B,DIAPH3,LINC00442,FAM71C,LMNB1" MicroRNA hsa-miR-409-3p:mirSVR_highEffct hsa-miR-409-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.96E-40 3.17E-36 5.87E-38 5.38E-37 85 1233 "ABL2,BIRC6,ANKRD34B,MSH2,CCNA1,CDKL2,CAMK4,CAST,FCHO2,SNTG2,PCCA,ZMYM5,CDK7,WDFY2,MRPL57,JAKMIP1,ADGRF3,HECTD1,AKAP6,RCHY1,SYCP3,CLOCK,LACC1,CSNK1G3,TTC37,VCAN,ZFYVE16,MATR3,LOC439933,COCH,TBC1D4,OCIAD1,SACS,C14orf119,ATG10,CLIP4,RNASEL,KLHL12,MARVELD2,STX2,ARSK,ABCA11P,FCGR2B,NDUFAF7,GORAB,FGF9,PAICS,UFM1,TADA1,SLC15A4,SLC22A4,NR5A2,LIMCH1,GABRA2,GABRB1,KDM5B,ERAP1,NPAS3,RBKS,LRCH1,ERBIN,SCFD1,GPR12,STON1,EML4,TEP1,MSH6,LINC01551,RASSF6,ACTR6,TMPO,ZNF721,TECRL,SLAIN1,TENT2,HTR2A,WDR36,FCRL6,MZF1,ZMYM2,LHX9,NPHS2,RNASE11,LINC01913,RMST" MicroRNA hsa-miR-26a:mirSVR_lowEffct hsa-miR-26a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-39 6.53E-36 1.19E-37 1.09E-36 104 1911 "MAP1B,NLN,BLZF1,ARHGAP5,ARL1,STARD13,BCL2L2,NOVA1,ODC1,FCHO2,ZNF664,FAM177A1,XPR1,PDGFRA,CENPC,RCBTB2,CHD1,PFKFB2,SLC25A3,GPR180,MRPL57,SNX6,THAP6,HOMER1,AKAP6,GNPTAB,POU2F1,SYCP3,PREPL,LACC1,IL20,ITSN2,DDX59,MATR3,KLHL3,NUDT12,OCIAD1,PTPRH,RABGAP1L,GALNT14,TMEM161B,AASDH,REST,TMEM33,MBNL2,EIF2B1,ETF1,PCGF3,TNFRSF19,POLK,FOXO1,SUPT20H,ALKAL2,NUBPL,TADA1,SLC12A2,N4BP2,C1orf112,NR5A2,YPEL5,UGGT2,KIF21B,CENPJ,IQGAP2,GJB6,OXGR1,KDM3B,CMPK2,LRCH1,KLHL20,GJA3,ZNF544,UGT2A1,SCFD1,PPIP5K2,ANO4,C5orf56,GPR12,ARHGEF28,KMT5A,KMT5C,RNF212,GRSF1,NPL,STARD4,NSD2,YTHDC2,IGF1,ZNF84,ZMYM2,ZBTB41,LHX9,TMEM178A,CAB39L,DIAPH3,KIR2DL1,KIR2DL4,KIR3DL1,KIR3DL2,AMTN,LETM1,AXDND1,LOX,MICU2" MicroRNA hsa-miR-218-2*:mirSVR_lowEffct hsa-miR-218-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.04E-39 1.08E-35 1.93E-37 1.77E-36 100 1773 "MATN3,BIRC6,KIAA1211,ANKRD34B,FBRSL1,CDKL4,MSH2,FAM193A,CD84,BTF3,LINC02347,CDKL2,MORN2,CHAMP1,CD1E,PCSK1,PDE4D,CENPC,NRXN1,ADGRF3,PTPRVP,HOMER1,GNPTAB,BRI3BP,C12orf65,LRRTM2,CEP135,FCRL5,FCRL2,SNX17,COG3,PTPRC,MTX3,DHFR,PARPBP,C14orf119,NR1H4,B3GLCT,RASA1,CLIP4,SETDB2,RNF4,TBC1D19,ZNF671,DEPDC4,DRAM1,CWC27,MAEA,ABCA11P,ADGRV1,PCGF3,F10,N4BP2L2,PIBF1,SUCO,FTLP10,STAB2,SUPT20H,FBXO11,NBEA,DDX51,SCYL2,TADA1,SLC12A2,PKD2L2,C1orf112,ZNF667,GABRB1,RAPGEF6,CD244,KDM3B,SRP72,GC,ANKLE2,BRD8,PPIP5K2,C5orf56,TCF7,YIPF7,TDG,TEP1,GTF3C2,HAL,ATP6V0A2,HEXB,ADAMTS19,TECRL,RXFP2,SLAIN1,NSD2,ITLN2,ZNF10,KCNT2,TADA2B,ZNF84,LHX9,TDRD3,KIT,LAD1,ZNF304" MicroRNA hsa-miR-297:mirSVR_highEffct hsa-miR-297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.45E-39 1.30E-35 2.29E-37 2.10E-36 87 1322 "MATN3,BIRC6,KIAA1211,COG6,NCOA1,SLC4A4,CADM3,CD84,ARHGEF7,CCNA1,CAMK4,FCGR2C,CDK7,CFAP54,NRXN1,HECTD1,THAP6,HOMER1,STRN3,CLOCK,C12orf65,FCRL5,BIVM,COG3,TBC1D4,PTPRC,PARPBP,DNMT3A,RB1,NTN4,RNASEL,MBNL2,DCUN1D2,MARVELD2,BORA,CWC27,SAP18,ETF1,CLIP1,SH3YL1,TRAPPC13,FCGR3A,FCGR3B,FGF9,SUCO,FLT1,TADA1,CCDC88A,ZNF605,ZNF667,YPEL5,ACIN1,MYO16,MEGF10,GABRB1,KIF21B,NPAS3,LRCH1,IKBIP,MIMT1,PPARGC1A,GJA3,TMED2,METAP2,ADGRL3,ANO4,TDG,CRB1,TMPO,HEXB,ADAMTS19,TECRL,NSD2,FCRL6,ZNF140,ANKS1B,LMLN,FIP1L1,KIF2A,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,RNASE11,SPRYD7,AXDND1" MicroRNA hsa-miR-675*:mirSVR_lowEffct hsa-miR-675*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.80E-39 1.49E-35 2.56E-37 2.35E-36 80 1100 "MATN3,BIRC6,COG6,EP400,APBB2,NCOA1,CD84,CCNA1,FCHO2,SNTG2,XPR1,CDK7,NRXN1,PIGR,POLN,HECTD1,THAP6,HOMER1,C1orf116,STRN3,SNCAIP,ZNF586,DMXL1,COCH,PTPRC,PARPBP,TSEN15,NR1H4,DNMT3A,FAM129A,RB1,AASDH,TXNDC15,MBNL2,TBC1D19,SAP18,ETF1,CLIP1,ELOVL7,FCAR,FCGR3A,FCGR3B,FGFR3,PIBF1,POLK,FLT1,SUPT20H,MBIP,IVNS1ABP,SLC12A2,C1orf112,SLC22A4,FSHR,YPEL5,GC,LRCH1,IKBIP,PSME4,UGT2A1,ADAM17,ANO4,COX18,GRSF1,RAB2B,TMPO,HEXB,TRPC4,SLAIN1,ZNF876P,NSD2,YTHDC2,ANKS1B,ZBTB41,LHX9,DNAH10,LINC01913,RMST,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-499-5p:mirSVR_lowEffct hsa-miR-499-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.18E-39 1.69E-35 2.86E-37 2.62E-36 96 1637 "MAP1B,MCC,TMEM132B,COG6,MCFD2,UVSSA,APC,BLZF1,WDR19,ASCL1,ZNF542P,KCTD12,PPP1R12B,ARHGEF7,NFKBIA,MORN2,CHAMP1,TSSK4,PCDH9,DCLK1,FAM177A1,XPR1,PGGT1B,NRXN1,PIGR,C1orf116,STRN3,RCHY1,SYCP3,HEATR5A,FAM169A,DNM3,ZFYVE16,PIGG,SREK1,DMXL1,FBXL5,CEP350,OCIAD1,F11R,SUPT7L,PPP2R3C,DNMT3A,OGFOD2,SLC9C2,RGS12,LRPPRC,PACRGL,TBC1D19,ETF1,USP44,NDUFAF7,FNIP1,SUCO,FLT1,SUPT20H,FBXO11,SLC30A6,SCYL2,CCDC88A,SLC22A5,UGGT2,MEGF10,PDS5B,TMEM183A,CD244,ERAP1,HSPH1,SRP72,GCKR,KLHL20,PCDH17,TMED2,GPR12,DOCK9,XPO4,TEP1,TFDP1,BAZ1A,RASSF6,ACTR6,HEXB,TRPC4,TECRL,STARD4,ZNF10,IGF1,IL6ST,ANKS1B,CHPT1,LMLN,KIF3C,DIAPH3,RNASE11,RMST,MICU2" MicroRNA hsa-miR-425:mirSVR_lowEffct hsa-miR-425:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-39 2.91E-35 4.86E-37 4.45E-36 101 1831 "MAP1B,ACOX3,KIAA1211,ANKRD34B,CUL4A,AACS,SLC5A6,PNP,DAOA,CHAMP1,PCCA,PCDH9,RGSL1,PDE4D,PDGFRA,PFKFB2,CCDC122,WDFY2,SLC25A3,BOD1L1,TAPT1,RCHY1,SNCAIP,CSNK1G3,CEP135,FAM169A,DNM3,ZFYVE16,IFT172,MATR3,BIVM,COG3,DMXL1,FBXL5,PTPRC,F11R,WDR1,RAN,FAM129A,RASA1,OGFOD2,EIF2B1,SPATA9,UGT2A3,KLHL12,FAM172A,DLEU1,PCGF3,TOMM40L,FGF9,RELL1,TACC3,PIBF1,FLT1,SUPT20H,ZCCHC8,SLC34A2,G2E3,MBIP,THADA,ZNF605,TMEM132D,C1orf112,EFR3B,UGGT2,MYT1L,PDS5B,NMNAT2,ZNF274,ERAP1,NPAS3,GJA3,GJB2,INSM2,ATP11A,COX7B2,PPIP5K2,METAP2,ADGRA3,ANO4,ACSL6,KMT5A,RNF212,TEP1,ACTR6,TNR,NPL,HSP90B1,GUF1,SLAIN1,PAPPA2,ZNF84,CCDC169,ZMYM2,LHX9,FAM151B,TMEM178A,CAB39L,KIR2DS4,AXDND1,ZDHHC20" MicroRNA hsa-miR-616:mirSVR_lowEffct hsa-miR-616:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.04E-39 3.21E-35 5.27E-37 4.82E-36 99 1759 "MAP1B,TMEM132B,SLAMF6,NYNRIN,SEMA6A,RGS5,MSH2,FAM193A,ATP1A2,NFATC4,RAB29,ADGRD1,NOVA1,DAOA,MORN2,UHMK1,RFLNA,PCSK1,PDE4D,VIT,ZNF595,CFAP54,TM9SF2,PIK3C2B,BOD1L1,HECTD1,THAP6,C1orf116,AKAP6,COPA,RCHY1,VCAN,EIF2AK2,GLT8D2,DDX59,BIVM,COG3,PTGS2,DMXL1,TBC1D4,CEP120,PTPRC,RABGAP1L,LAP3,NTN4,LATS2,MBNL2,SNORA53,TBC1D19,DRAM1,DNAJC27,ABCA11P,ADGRV1,PCGF3,F7,TRAPPC13,RELL1,POLK,STAB2,NUBPL,IVNS1ABP,CCDC88A,PKD2L2,TMEM132D,UGGT2,MYO16,MYT1L,PDS5B,RAPGEF6,IQGAP2,HSPH1,NPAS3,ANKLE2,ERBIN,PCDH17,PSME4,COX7B2,ADGRL3,ANO4,ACSL6,C5orf56,KHNYN,NT5C1B,ADAMTS19,TECRL,TMEM174,HPCAL1,ZNF10,JCHAIN,IL6ST,CCDC169,PLB1,ANKS1B,ZBTB41,ZBED3-AS1,CHPT1,TMEM178A,LIG4,CDK2AP1" MicroRNA hsa-miR-590-3p:PITA hsa-miR-590-3p:PITA_TOP PITA 7.27E-39 3.86E-35 6.23E-37 5.71E-36 91 1477 "ABL2,MDM4,ADD1,NLN,TBC1D14,HOMEZ,CUL4A,EP400,APAF1,APC,WDR19,ARHGAP5,NCOA1,SLC4A4,STARD13,KCTD12,CDKL2,CHAMP1,CCNB1,NFXL1,PCDH9,FAM177A1,XPR1,CDK17,PDE4D,CFL2,PFKFB2,BOD1L1,THAP6,AKAP6,STRN3,RCHY1,LYSMD3,CLOCK,NGDN,CEP135,DNM3,UBXN2A,DCAF8,BIVM,SREK1,KLHL3,NUDT12,B3GLCT,RB1,TMEM161B,SMC6,LATS2,MBNL2,ELF1,PCGF3,CLIP1,IRF9,TNFRSF19,FOXG1,FLT3,FBXO11,BRMS1L,UFM1,SLC8A1,CCDC88A,SLC12A2,N4BP2,PDS5B,RAPGEF6,ATP8A2,SRP54,ERBIN,PCDH17,PPARGC1A,STRN,TMED2,ATP11A,METAP2,ADGRL3,ANO4,XPO4,TDG,GRSF1,TFDP1,SLC7A8,BAZ1A,RIMBP2,ZNF721,ADAMTS19,KLF12,NSD2,KCNT2,SPTSSA,ZBTB41,LHX9" MicroRNA hsa-miR-301b:mirSVR_highEffct hsa-miR-301b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.57E-39 4.56E-35 7.24E-37 6.63E-36 95 1621 "RALGAPA1,MATN3,MDM4,BIRC6,KIAA1211,WDR35,APAF1,APC,BLZF1,WDR19,ARL1,NCOA1,ATP12A,ZNF542P,STARD13,CD84,DAOA,CDKL2,CAST,PCDH9,CDK17,PDGFRA,CFL2,PFKFB2,JAKMIP1,HOMER1,RCHY1,FAM53A,GNPTAB,HEATR5A,LYSMD3,CLOCK,DNM3,DCAF8,PTGS2,FBXL5,NUDT12,CEP120,PARPBP,FAM129A,RASA1,AASDH,MEMO1,RNF4,ELK3,MPHOSPH9,SAP18,CLIP1,F10,NDUFAF7,GORAB,N4BP2L2,TNFRSF19,PEAR1,FLT1,VEZT,FBXO11,NBEA,SLC8A1,CCDC88A,C1orf112,SLC22A5,ZNF667,MEGF10,MYT1L,ZNF274,ERAP1,CMPK2,LRCH1,ERBIN,IKBIP,KLHL20,CFHR4,NPFFR2,INSM2,RNF17,ADAMTS19,TXK,UBC,SLAIN1,TENT2,C12orf73,ZMYM2,IRF1,FAM49A,CHPT1,LMLN,CAB39L,DIAPH3,TTC41P,DNAH10,RMST,NUAK2,LIG4,LMNB1" MicroRNA hsa-miR-218:mirSVR_highEffct hsa-miR-218:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.05E-38 5.56E-35 8.69E-37 7.96E-36 85 1281 "RALGAPA1,BIRC6,COG6,SNX24,CBLN3,TAF1B,FCHO2,FCGR2C,CD1E,PCDH9,CDK17,PDGFRA,CFAP54,NRXN1,THAP6,COPA,THTPA,LYSMD3,PREPL,CRHBP,SNCAIP,CEP135,FCRL5,BIVM,COCH,SACS,RABGAP1L,TSEN15,RNF219,EGLN3,REST,EIF2D,PACRGL,GRTP1,MBNL2,SNORA49,FAM172A,NDUFAF7,GORAB,POLK,HSD17B7,SUPT20H,ZNF446,SLC8A1,CCDC88A,ZNF605,SLC12A2,C1orf112,MYO16,MYT1L,PDS5B,ERAP1,SRP72,LRCH1,ERBIN,ZBTB37,LPIN1,MAST4,COX7B2,ANO4,C5orf56,TCF7,DOCK9,NT5C1B,ZBTB49,ACTR6,TMPO,RIMBP2,TECRL,GUF1,RXFP2,TENT2,PAPPA2,VRK2,ZNF470,C12orf73,LHX9,ZBED3-AS1,CAB39L,KIF2A,KIT,LCP1,RMST,LMNB1,LOX" MicroRNA hsa-miR-802:mirSVR_lowEffct hsa-miR-802:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-38 5.93E-35 9.13E-37 8.36E-36 100 1809 "MDM4,ADD1,WDR35,SEMA6A,HOMEZ,PITPNM2,RGS5,FBRSL1,APBB2,ASCL1,SLC4A4,ZNF542P,ATP4B,KCTD12,BCL2L2,ARHGEF7,NFKBIA,NOVA1,CDKL2,CAST,NFXL1,PCK2,XPR1,PDGFRA,PFKFB2,PGGT1B,GPR180,NRXN1,SNX6,PIK3C2B,ATAD2B,THAP6,GNPTAB,TOGARAM2,PREPL,CRHBP,SNCAIP,LACC1,DCAF8,KLHL3,DNMT3A,FAM129A,TMEM161B,OGFOD2,REST,NTN4,SETDB2,LRPPRC,PACRGL,RNF4,STX2,FAM172A,FNIP1,TNFRSF19,FGFR3,RELL1,POLK,FOXG1,PEAR1,SELP,FLT1,FTLP10,SUPT20H,BRMS1L,NLRP2,THADA,ARHGEF40,C1orf112,LIMCH1,CPSF3,MYO16,KIF21B,KDM5B,NMNAT2,UHRF1BP1L,ATP8A2,KDM3B,MCCC2,PSME4,TBC1D1,TMED2,ADAM17,SCFD1,GPR12,ARHGEF28,STON1,EML4,RNF17,GRSF1,BAZ1A,TMPO,RIMBP2,TRPC4,ZNF550,POC5,ZBTB41,LMLN,FIP1L1,LMNB1,ZNF304" MicroRNA hsa-miR-137:mirSVR_highEffct hsa-miR-137:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-38 6.80E-35 1.03E-36 9.44E-36 95 1629 "MDM4,ANKRD34B,COG6,CUL4A,BLZF1,KCTD12,CD84,ARHGEF7,NOVA1,AMDHD1,FCHO2,CHAMP1,UHMK1,DCLK1,ZMYM5,RGSL1,PDGFRA,CHD1,NRXN1,SNX6,ATAD2B,STRN3,COPA,GNPTAB,LACC1,CSNK1G3,ZFYVE16,PTGS2,COCH,TBC1D4,DHFR,LINC01257,SMC6,AASDH,POLR1D,RNASEL,GRTP1,MBNL2,UGT2A3,TBC1D19,SAP18,ABCA11P,ADGRV1,ELOVL7,TOMM40L,NDUFAF7,FGF9,RELL1,PIBF1,FMO1,SUPT20H,VEZT,SGCG,NBEA,SLC8A1,ZNF605,SLC12A2,LIMCH1,MEGF10,KDM5B,NMNAT2,SRP72,NEDD1,ERBIN,PPARGC1A,TBC1D1,SCFD1,METAP2,ADGRA3,SPIC,ANO4,ACSL6,RNF212,BAZ1A,RAB2B,TMPO,MAEL,ZNF721,HEXB,UBE2K,SLAIN1,STARD4,ZNF26,KCNT2,ZNF140,CCDC190,ANKS1B,FAM151B,TDRD3,CHPT1,KIT,RMST,AXDND1,CDK2AP1,IFT88" MicroRNA hsa-miR-301b:mirSVR_lowEffct hsa-miR-301b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-38 8.61E-35 1.29E-36 1.18E-35 100 1817 "MAP1B,MCC,ADD1,NLN,PITPNM2,ZNF784,ASCL1,CENPBD1P1,ATP1A2,SLC4A4,KCTD12,MYH6,NFATC4,AP1G2,NOVA1,RILPL1,UHMK1,PDE4D,CEBPE,CHD1,TM9SF2,PKP1,HECTD1,STRN3,TAPT1,ITSN2,LRRTM2,FAM169A,SNX17,COG3,KLHL3,TBC1D4,G3BP2,SUPT7L,WDR1,PPP2R3C,C14orf119,RNF219,EGLN3,ATG10,OGFOD2,TMEM33,CLIP4,LRPPRC,RNASEL,EFNA5,ELF1,KLHL12,FCAMR,ZNF671,PCBD2,PIBF1,POLK,FOXG1,HSD17B7,STAB2,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,RAPGEF6,TMEM183A,IQGAP2,GJB6,RBKS,NEDD1,PCDH17,COMMD6,PPARGC1A,ATP11A,MTUS2,ADGRA3,ARHGEF28,DOCK9,COX18,CRB1,TGM1,LINC01551,RAB2B,RIMBP2,ATP6V0A2,NPL,TPO,HSP90B1,UBE2K,RXFP2,WDR36,NSD2,ZNF10,IGF1,ZBTB41,LHX9,FAM151B,KCNN2,FIP1L1,KIT,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-301a:mirSVR_lowEffct hsa-miR-301a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.24E-38 1.19E-34 1.75E-36 1.60E-35 100 1824 "MAP1B,MCC,ADD1,NLN,PITPNM2,RGS5,ZNF784,WDR19,ASCL1,CENPBD1P1,ATP1A2,KCTD12,MYH6,NFATC4,AP1G2,NOVA1,UHMK1,DCLK1,PDE4D,CEBPE,CHD1,TM9SF2,PKP1,HECTD1,STRN3,TAPT1,ITSN2,LRRTM2,FAM169A,SNX17,COG3,KLHL3,TBC1D4,G3BP2,SUPT7L,WDR1,PPP2R3C,C14orf119,RNF219,EGLN3,FAM129A,ATG10,OGFOD2,TMEM33,CLIP4,LRPPRC,RNASEL,EFNA5,ELF1,FCAMR,ZNF671,PCBD2,FOXG1,FLT1,HSD17B7,STAB2,SUPT20H,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,JPH4,RAPGEF6,TMEM183A,ZNF274,IQGAP2,GJB6,NPAS3,RBKS,NEDD1,PCDH17,COMMD6,PPARGC1A,ATP11A,ADGRA3,ARHGEF28,COX18,CRB1,TGM1,LINC01551,RIMBP2,ATP6V0A2,NPL,TPO,HSP90B1,UBE2K,RXFP2,NSD2,ZNF10,IGF1,ZBTB41,LHX9,FAM151B,KCNN2,FIP1L1,KIT,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-217:mirSVR_lowEffct hsa-miR-217:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.73E-38 1.45E-34 2.11E-36 1.93E-35 99 1791 "MAP1B,BIRC6,ADD1,ACOX3,KIAA1211,SLAMF6,ATP6V1G3,NYNRIN,SEMA6A,CUL4A,UVSSA,SLC4A4,ZNF542P,KCTD12,FGFRL1,FCRL3,NFXL1,PCCA,DCLK1,CDK17,CFL2,PFKFB2,CCDC122,CHIT1,COLEC11,SMIM14,SNX6,ATAD2B,POLN,TAPT1,LYSMD3,CLOCK,CSNK1G3,VCAN,C12orf65,FAM169A,DNM3,FCRL5,COG3,DMXL1,CEP120,PARPBP,RAN,B3GLCT,RASA1,TMEM33,MARVELD2,STK32B,DLEU1,PCGF3,ELOVL7,FCGR3A,FCGR3B,POLK,SUCO,FOXG1,PEAR1,FLT1,RUBCNL,SLC34A2,PLEKHA6,NUBPL,SLC30A6,THADA,SLC12A2,N4BP2,NR5A2,MEGF10,JPH4,RAPGEF6,CD244,LILRB1,PCDH17,MTUS2,ANO4,ACSL6,TCF7,KMT5A,DOCK9,KHNYN,RNF212,RNF17,GRSF1,ZBTB49,TMPO,ATP6V0A2,ADAMTS19,GUF1,NSD2,SELENOI,ZBTB41,LHX9,NPHS2,LMLN,KCNN2,TTC41P,RMST,AXDND1,CDK2AP1" MicroRNA hsa-miR-1259:mirSVR_highEffct hsa-miR-1259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.82E-38 1.50E-34 2.15E-36 1.96E-35 94 1609 "ABL2,MAP1B,MATN3,KIAA1211,NLN,ANKRD34B,COG6,WDR35,APAF1,CDKL4,ARHGAP5,ATP1A2,SLC4A4,KCTD12,ATP7B,NEDD8,ADGRD1,TAF1B,PAH,PCDH9,FAM177A1,PCSK1,RGSL1,PGGT1B,STRN3,RCHY1,PREPL,VCAN,ITSN2,LRRTM2,CEP135,PSMA6,BIVM,SREK1,PTGS2,PTPRC,RABGAP1L,NR1H4,RAN,DTD2,POLR1D,NTN4,UGT2A3,ELF1,FAM172A,DRAM1,PCBD2,FCGR2B,NDUFAF7,N4BP2L2,RELL1,POLK,FLT1,ZCCHC8,NBEA,ALKAL2,TADA1,SLC12A2,C1orf112,YPEL5,EFR3B,GABRA2,KIF21B,PDS5B,RAPGEF6,CD244,NPAS3,SRP72,ERBIN,PPARGC1A,STRN,ATP11A,PPIP5K2,METAP2,MTUS2,ADGRL3,ADGRA3,TCF7,EML4,RNF212,TDG,RNF17,TGFBI,ADAMTS19,TECRL,WDR36,YTHDC2,KCNT2,TADA2B,C12orf73,ANKS1B,LHX9,SPRYD7,AXDND1" MicroRNA hsa-miR-218:mirSVR_lowEffct hsa-miR-218:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.45E-38 1.84E-34 2.58E-36 2.37E-35 99 1796 "SFTA3,MCC,TMEM132B,KIAA1211,SEMA6A,UVSSA,BLZF1,ARHGAP5,AACS,ATP1A2,KCTD12,CD84,ARHGEF7,ADGRD1,NOVA1,CDKL2,PCCA,WDR66,RGSL1,PDE4D,GLT1D1,CFL2,CHIT1,GPR180,ITGBL1,BOD1L1,TTC37,C12orf65,KIAA0040,DCAF8,ZFYVE16,SPATA18,KLHL3,NUDT12,PTPRC,DHFR,SUPT7L,LINC01257,WDR1,B3GLCT,RNF31,RASA1,TMEM33,POLR1D,EFNA5,TXNDC15,EIF2B1,SPATA9,KLHL12,STX2,FAM81B,CWC27,ABCA11P,PCBD2,TMEM129,FCGR3A,FCGR3B,RELL1,PIBF1,FLT1,VEZT,RUBCNL,G2E3,DDX51,SLC30A6,IVNS1ABP,CGREF1,YPEL5,CHFR,CYP1B1-AS1,KIF21B,NMNAT2,KDM3B,MCCC2,IKBIP,PCDH17,PPARGC1A,PSME4,LINC02393,METAP2,ADGRL3,GPR12,ARHGEF28,BAZ1A,RASSF6,GPN1,SLAIN1,HSD17B4,FCRL6,IL6ST,CCDC169,IRF1,TMEM178A,LMLN,KCNN2,AMTN,LAD1,LINC01913,AXDND1" MicroRNA hsa-miR-1298:mirSVR_lowEffct hsa-miR-1298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.68E-38 1.96E-34 2.72E-36 2.49E-35 77 1047 "RALGAPA1,MATN3,COG6,APC,MSH2,ARL1,NOP14,FCRL3,ARHGEF7,ADGRD1,NOVA1,GLT1D1,RCBTB2,CHD1,ZNF595,SLC25A3,SMIM14,JAKMIP1,ADGRF3,AKAP6,TTC37,VCAN,PRKD1,GLT8D2,SPATA18,COG3,DMXL1,LOC439933,NUDT12,OCIAD1,GNPDA2,DHFR,TMEM161B,RNF4,DCUN1D2,ELK3,CWC27,TRAPPC13,FCGR3A,TOMM40L,FCGR3B,SUCO,TM9SF1,SLC34A2,TADA1,CCDC88A,PKD2L2,POTEM,FSHR,YPEL5,EFR3B,UGGT2,PDS5B,IQGAP2,NEDD1,COMMD6,BRD8,MAST4,ADGRA3,C5orf56,EML4,RNF212,RNF17,BAZ1A,ACTR6,HAL,ADAMTS19,VRK2,IGF1,PLB1,CCDC190,ANKS1B,ZMYM2,FIP1L1,SLAMF9,ZDHHC20,IFT88" MicroRNA hsa-miR-502-5p:mirSVR_lowEffct hsa-miR-502-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.35E-38 2.31E-34 3.17E-36 2.90E-35 99 1801 "MATN3,ADD1,COG6,CUL4A,SNX24,CDKL4,NOP14,CENPBD1P1,ATP2B4,CADM3,ATP7B,CARMIL3,BTF3,DAOA,CAD,MPZL1,RILPL1,SCFD2,CHD1,CFAP54,NRXN1,PIK3C2B,AKAP6,STRN3,RCHY1,POU2F1,LYSMD3,LACC1,FAM169A,NOS1AP,FCRL2,IFT172,SNX17,BIVM,PIGG,SREK1,COG3,KLHL3,TBC1D4,F11R,PPP2R3C,FAM129A,OGFOD2,TMEM33,CLIP4,POLR1D,RNASEL,EFNA5,TXNDC15,DCUN1D2,EIF2B1,MARVELD2,ARSK,ABCA11P,ADGRV1,F7,F10,ARL6IP4,NDUFAF7,POLK,SDC1,G2E3,ZNF446,SLC8A1,THADA,ZNF605,PKD2L2,C1orf112,SLC22A4,ACIN1,UGGT2,MEGF10,MYT1L,ERAP1,ATP8A2,MCCC2,ANKLE2,KLHL20,ZBTB37,PPARGC1A,ZNF544,TMED2,CNTN2,C5orf56,TCF7,ARHGEF28,KMT5A,RAB2B,RIMBP2,MAEL,NPL,HSD17B4,VRK2,HTR2A,DIAPH3,KIR2DL4,TTC41P,SLAMF9,IFT88" MicroRNA hsa-miR-155:mirSVR_lowEffct hsa-miR-155:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.88E-38 2.60E-34 3.51E-36 3.21E-35 100 1841 "RALGAPA1,BIRC6,SLAMF6,COG6,MCFD2,ARHGAP5,ASTN1,SLC4A4,KCTD12,PAH,RFLNA,ZNF664,CDK7,CHIT1,PGGT1B,CFAP54,TM9SF2,SNX6,JAKMIP1,HECTD1,THAP6,PMCH,RCHY1,PREPL,C12orf65,NOS1AP,SNX17,PIGG,COG3,DMXL1,DHX9,CEP350,PTPRC,RABGAP1L,DHFR,C12orf42,C14orf119,NR1I3,EGLN3,SLC9C2,TMEM33,MEMO1,ELK3,FCAMR,SAP18,ETF1,ADGRV1,USP44,NDUFAF7,RELL1,PIBF1,POLK,FOXG1,SUPT20H,VEZT,SH3BP2,BRMS1L,MBIP,POTEM,NR5A2,GABRA2,PDS5B,RAPGEF6,HSPH1,SRP54,SRP72,COMMD6,SULT1E1,PPARGC1A,MAST4,TMED2,GOLGA3,ADGRA3,ARHGEF28,STON1,RNF17,ZBTB49,GTF2H3,HEXB,HMGCR,SLAIN1,HSD17B4,ZNF876P,WDR36,NSD2,IGF1,MZF1,ZNF470,ZNF84,SELENOI,C12orf73,GALP,ZBTB41,FAM151B,NPHS2,TMEM178A,KIF2A,TTC41P,LMNB1,CDK2AP1" MicroRNA hsa-miR-367*:mirSVR_lowEffct hsa-miR-367*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.05E-38 2.69E-34 3.56E-36 3.26E-35 97 1730 "SMIM15,ADORA1,KIAA1211,DHX37,APC,MSH2,DDX55,WDR19,FAM193A,CCNB1IP1,NOVA1,CDKL2,CAMK4,LDB2,PCDH9,PCSK1,CDK18,CHD1,GPR180,ATAD2B,POLN,PTPRVP,SNCAIP,TTC37,C12orf65,LRRTM2,DNM3,UBXN2A,PRKD1,ZNF586,COG3,G3BP2,DHFR,C12orf42,DNMT3A,EGLN3,TMEM161B,OGFOD2,RGS4,RGS12,TMEM33,MEMO1,MBNL2,MARVELD2,TBC1D19,DEPDC4,ARSK,ABCA11P,ADGRV1,F10,ELOVL7,USP44,FNIP1,FGF9,PIBF1,SUCO,SDC1,FOXO1,SUPT20H,UFM1,ZNF605,ZNF667,MEGF10,GABRA2,GABRB1,PDS5B,NAAA,ERAP1,NPAS3,NFASC,DRC1,LRCH1,KLHL20,PCDH17,GJA3,PSME4,ANO4,GPR12,DOCK9,KHNYN,RNF17,AP4S1,GTF2H3,TNR,UBE2K,HTR2A,ZNF324B,SPTSSA,GALP,ANKS1B,CHPT1,ANKDD1B,EP400P1,LCP1,FAM71C,SPRYD7,LMNB1" MicroRNA hsa-miR-101:mirSVR_lowEffct hsa-miR-101:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-38 2.70E-34 3.56E-36 3.26E-35 103 1956 "SMIM15,TMEM132B,NLN,COG6,CUL4A,EP400,DHX37,APC,SLC4A4,STARD13,NFKBIA,CCNA1,CBLN3,CAST,FCHO2,XPR1,CDK17,PDE4D,PDGFRA,PFKFB2,PGGT1B,SLC25A3,TM9SF2,SNX6,ATAD2B,AKAP6,STRN3,FAM163A,TAPT1,ITSN2,FAM169A,ZNF586,SPATA18,SREK1,CEP350,PTPRC,F11R,SACS,G3BP2,GNPDA2,SLC35F6,RAN,AASDH,IPO4,LRPPRC,RNASEL,SPATA9,UGT2A3,TBC1D19,GP6,FAM172A,CWC27,ADGRV1,PCGF3,CLIP1,TRAPPC13,TOMM40L,FGFR3,POLK,MROH9,FLT1,FMO1,VEZT,FBXO11,PLEKHA6,NUBPL,ARHGEF40,C1orf112,FSHR,EFR3B,MEGF10,GABRB1,EAPP,ATP8A2,HSPH1,NPAS3,SRP54,LRCH1,MIMT1,NMU,PPARGC1A,STRN,UGT2A1,ANO4,XPO4,RNF17,GRSF1,TFDP1,CRB1,GPR161,LINC01551,BAZ1A,ADAMTS19,UBE2K,TUBA3C,SLAIN1,WDR36,ZBTB41,TMEM178A,KIF2A,RMST,IFT88,PABPN1" MicroRNA hsa-miR-628-3p:mirSVR_lowEffct hsa-miR-628-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.34E-38 2.84E-34 3.69E-36 3.37E-35 91 1515 "BIRC6,NLN,RGS5,APAF1,FBRSL1,ARL1,STXBP6,CCDC181,ATP4B,STARD13,BCL2L2,ARHGEF7,TAF1B,CD1E,PAH,NFXL1,FCRLB,SLC5A8,PIWIL1,ZNF595,NRXN1,ATAD2B,BOD1L1,ADGRF3,POLN,AKAP6,FAM163A,GNPTAB,SNCAIP,VCAN,CEP135,DCAF8,NUDT12,PTPRC,TINF2,SLC35F6,PARPBP,TSEN15,EGLN3,RB1,MEMO1,SETDB2,LATS2,MBNL2,MPHOSPH9,MARVELD2,STX2,ARSK,ETF1,FNIP1,TNFRSF19,PIBF1,FOXG1,FBXO11,NBEA,UFM1,TMEM132D,SLC15A4,UGGT2,CYP1B1-AS1,MYO16,MYT1L,NMNAT2,UHRF1BP1L,MCCC2,NEDD1,PCDH17,LPIN1,SCFD1,PPIP5K2,METAP2,ADGRL3,SPIC,EML4,DOCK9,NT5C1B,TFDP1,CRB1,RAB2B,RIMBP2,MAEL,HEXB,HMGCR,ZNF550,PAPPA2,VRK2,IL25,KCNT2,ZNF84,FAM151B,DIAPH3" MicroRNA hsa-miR-517*:mirSVR_lowEffct hsa-miR-517*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.86E-38 3.12E-34 4.00E-36 3.66E-35 89 1447 "MAP1B,SMIM15,ADD1,FBRSL1,APBB2,RAD51AP2,NCOA1,ASTN1,ATP2B4,CADM3,BCL2L2,CD84,NFATC4,BTF3,NOVA1,CAST,CHAMP1,CD1D,FAM177A1,RGSL1,PDE4D,PDGFRA,MRPL57,SMIM14,C12orf65,ZFYVE16,SREK1,COG3,GNPDA2,PPP2R3C,TMEM161B,TMEM33,CLIP4,TXNDC15,DCUN1D2,ELK3,KLHL12,FAM81B,SAP18,GMPR2,PCGF3,CLIP1,ELOVL7,SH3YL1,TOMM40L,FCGR3B,TNFRSF19,MROH9,FMO1,FBXO11,PLEKHA6,TADA1,CCDC88A,EFR3B,DCAF11,CYP1B1-AS1,SNRPF,MYO16,GABRA2,IQGAP2,CMPK2,NFASC,KLHL20,PPARGC1A,UGT2A1,INSM2,PPIP5K2,ADGRL3,ARHGEF28,STON1,TEP1,GTF3C2,ACTR6,SLAIN1,HTR2A,NSD2,JCHAIN,ZFHX2,SPTSSA,ANKS1B,IRF1,SDR39U1,LHX9,CHPT1,KIT,TTC41P,LIG4,LMNB1,ZNF304" MicroRNA hsa-miR-452:mirSVR_highEffct hsa-miR-452:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.11E-38 4.31E-34 5.46E-36 5.00E-35 97 1740 "RALGAPA1,MATN3,IL17D,NLN,SEMA6A,HOMEZ,MSH2,ASCL1,NFKBIA,CACNA1E,CAST,FCHO2,CD1E,PCSK1,CENPC,GPR180,TM9SF2,ATAD2B,BOD1L1,HOMER1,ANAPC4,STRN3,TAPT1,CLOCK,FAM169A,PRKD1,MATR3,COG3,CEP350,G3BP2,RABGAP1L,LINC01257,PPP2R3C,DNMT3A,FAM129A,CLIP4,NTN4,EIF2D,RNASEL,EIF2B1,MPHOSPH9,DEPDC4,ARSK,ADGRV1,TLR6,PCGF3,FGFR3,PIBF1,VEZT,RUBCNL,FBXO11,G2E3,BRMS1L,GFM2,SLC8A1,THADA,ARHGEF40,CCDC88A,PKD2L2,SLC22A4,YPEL5,PUS1,UGGT2,LIMCH1,MYT1L,PDS5B,SRP54,DRC1,ERBIN,COMMD6,PPARGC1A,PSME4,PPIP5K2,DOCK9,FCRLA,RIMBP2,MAEL,GUF1,TENT2,VRK2,STARD4,ZNF10,TADA2B,IL6ST,ZNF140,CCDC190,ANKS1B,ZMYM2,TDRD3,CHPT1,ANKDD1B,FIP1L1,SPRYD7,LIG4,LMNB1,IFT88,PABPN1" MicroRNA hsa-miR-302e:mirSVR_lowEffct hsa-miR-302e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.09E-38 4.84E-34 6.04E-36 5.53E-35 99 1817 "ABL2,MCC,MDM4,BIRC6,ADD1,ULK1,FBRSL1,APC,ASTN1,CENPBD1P1,ATP12A,ATP7B,NFATC4,ARHGEF7,NOVA1,CD1D,UHMK1,DCLK1,PDE4D,ZNF595,WDFY2,GPR180,ITGBL1,ATAD2B,PKP1,TAPT1,GNPTAB,BRI3BP,FAM169A,PRKD1,DCAF8,ZFYVE16,PIGG,FBXL5,RNF219,B3GLCT,RNF31,RASA1,LAP3,SETDB2,GUSBP3,PACRGL,TXNDC15,MBNL2,ELK3,DEPDC4,SAP18,MAEA,ETF1,PCGF3,ARL6IP4,TMEM156,TOMM40L,FNIP1,SDC1,FLT1,SUPT20H,TM9SF1,NBEA,CCDC88A,WDCP,SLC22A5,KDM5B,ERAP1,GJB6,NPAS3,MRPS27,SRP54,DRC1,MCCC2,LRCH1,ERBIN,IKBIP,PCDH17,COMMD6,NPFFR2,ADAM17,ADGRL3,GPR161,ZBTB49,AP4S1,BAZ1A,RIMBP2,HEXB,TXK,SLAIN1,HTR2A,NSD2,ZNF470,IL6ST,IRF1,ZBTB41,LHX9,FAM151B,NPHS2,KIR2DL1,KIR2DS4,KIT,TTC41P" MicroRNA hsa-miR-135b:mirSVR_highEffct hsa-miR-135b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.92E-38 5.28E-34 6.52E-36 5.97E-35 86 1354 "MDM4,SNX24,APC,ATP1A2,CADM3,FCRL3,ARHGEF7,CAMK4,FCHO2,LDB2,PCCA,PCDH9,CDK17,PGGT1B,GPR180,ITGBL1,LINC01085,PMCH,STRN3,COPA,HEATR5A,EPGN,PREPL,CSNK1G3,VCAN,CEP135,UBXN2A,PRKD1,DMXL1,LOC439933,TBC1D4,LINC01257,PPP2R3C,B3GLCT,RNF31,RASA1,CLIP4,LATS2,SNORA49,ELK3,EFS,TMEM156,POLK,FOXO1,HSD17B7,FTLP10,STAB2,NBEA,UFM1,SLC8A1,TADA1,CCDC88A,ZNF605,C1orf112,ZNF667,GABRA2,PDS5B,NAAA,ERAP1,DRC1,NEDD1,LRCH1,BRD8,MAST4,MTUS2,CNTN2,ANO4,FCRLA,RNF17,NT5C1B,CRB1,NPL,ADAMTS19,GPN1,LTB4R2,YTHDC2,IL6ST,ZNF140,LHX9,FAM151B,DIAPH3,TTC41P,LINC01913,LCP1,RMST,IFT88" MicroRNA hsa-miR-224*:mirSVR_highEffct hsa-miR-224*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-37 5.43E-34 6.62E-36 6.06E-35 94 1635 "RALGAPA1,KIAA1211,NYNRIN,ARHGAP5,ASCL1,KCTD12,RAB29,DAOA,UHMK1,PDE4D,PDGFRA,CENPC,RCBTB2,ITGBL1,PIGR,ATAD2B,ADGRF3,HOMER1,AKAP6,MPC2,TAPT1,PREPL,SNCAIP,VCAN,MATR3,NUDT12,GNPDA2,DHFR,SUPT7L,FAM129A,B3GLCT,RASA1,FAM228A,SLC9C2,PACRGL,MBNL2,MPHOSPH9,ZNF671,DEPDC4,ARSK,ETF1,ADGRV1,CLIP1,USP44,FNIP1,RELL1,PIBF1,SUCO,FLT1,RASA3,VEZT,ZCCHC8,G2E3,NBEA,PAICS,THADA,TADA1,CCDC88A,SLC22A4,DCAF11,GABRB1,FAM114A1,NMNAT2,RAPGEF6,CENPJ,ATP8A2,HSPH1,CMPK2,PCDH17,COMMD6,NPFFR2,GJB2,INSM2,TMED2,PPIP5K2,STON1,TEP1,ZBTB49,LINC01551,HAL,HSP90B1,HTR2A,WDR36,KCNT2,C12orf73,CCDC169,FAM151B,TMEM178A,CAB39L,KIT,TTC41P,DNAH10,RMST,AXDND1" MicroRNA hsa-miR-21:mirSVR_lowEffct hsa-miR-21:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-37 5.58E-34 6.72E-36 6.15E-35 89 1458 "KIAA1211,NLN,NOP14,ASCL1,ATP2B4,KCTD12,FGFRL1,LINC02347,NOVA1,PNP,CACNA1E,MPZL1,UHMK1,PDE4D,PIWIL1,PFKFB2,WDFY2,SMIM14,ATAD2B,HOMER1,TAPT1,HEATR5A,CSNK1G3,ITSN2,LRRTM2,DNM3,NOS1AP,ZFYVE16,MATR3,PIGG,NUDT12,COCH,CEP120,PTPRC,OCIAD1,GNPDA2,SLC35F6,TMEM161B,CLIP4,RNASEL,TXNDC15,SPATA9,MPHOSPH9,MARVELD2,DLEU1,FOXG1,ZCCHC8,SGCG,NBEA,BRMS1L,PLEKHA6,ALKAL2,MBIP,SLC12A2,C1orf112,YPEL5,DCAF11,CYP1B1-AS1,RAPGEF6,NAAA,EAPP,HSPH1,NPAS3,NEDD1,IKBIP,LPIN1,GJB2,MAST4,CNTN2,ADGRA3,ANO4,KMT5C,TDG,COX18,NCSTN,CRB1,AP4S1,ACTR6,HEXB,HMGCR,GUF1,VRK2,JCHAIN,PLB1,ZBTB41,LHX9,LETM1,LMNB1,PABPN1" MicroRNA hsa-miR-154*:mirSVR_highEffct hsa-miR-154*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-37 7.92E-34 9.43E-36 8.63E-35 75 1007 "SMIM15,BIRC6,NLN,ANKRD34B,BLZF1,AACS,ASTN1,SLC4A4,STARD13,NFKBIA,CAST,FCHO2,LDB2,SNTG2,ZMYM5,CDK17,PDE4D,RCBTB2,ZNF595,SNX6,PIK3C2B,BOD1L1,EPN1,HEATR5A,LYSMD3,CRHBP,LRRTM2,COG3,CEP350,DNMT3A,LATS2,UGT2A3,DEPDC4,SAP18,USP44,GORAB,FGF9,SUCO,NBEA,TADA1,YPEL5,LIMCH1,MYT1L,KIF21B,PDS5B,NAAA,CD244,NPAS3,GC,ANKLE2,LRCH1,ERBIN,PPARGC1A,GJB2,PSME4,PPIP5K2,METAP2,ARHGEF28,EML4,MSH6,HMGCR,TENT2,NLRP8,KCNT2,ZNF470,ANKS1B,LHX9,TMEM178A,KCNN2,DIAPH3,KIT,TTC41P,SPRYD7,AXDND1,IFT88" MicroRNA hsa-miR-454:mirSVR_lowEffct hsa-miR-454:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-37 9.85E-34 1.16E-35 1.06E-34 98 1795 "MAP1B,MCC,ADD1,NLN,PITPNM2,RGS5,ZNF784,WDR19,ARHGAP5,ASCL1,CENPBD1P1,ATP1A2,MYH6,NFATC4,AP1G2,LINC02347,RAB29,NOVA1,RILPL1,UHMK1,PCCA,XPR1,PDE4D,CEBPE,CHD1,ITGBL1,PKP1,HECTD1,STRN3,TAPT1,ITSN2,LRRTM2,FAM169A,MATR3,SNX17,COG3,KLHL3,G3BP2,SUPT7L,WDR1,PPP2R3C,C14orf119,RNF219,EGLN3,FAM129A,CLIP4,LRPPRC,RNASEL,EFNA5,ELF1,FCAMR,ZNF671,TNFRSF19,RELL1,FOXG1,HSD17B7,STAB2,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,RAPGEF6,TMEM183A,ZNF274,IQGAP2,GJB6,NPAS3,RBKS,NEDD1,PCDH17,COMMD6,PPARGC1A,ATP11A,MTUS2,ADGRA3,GPR12,ARHGEF28,TGM1,LINC01551,RIMBP2,ATP6V0A2,NPL,HSP90B1,UBE2K,ZNF550,RXFP2,NSD2,IGF1,ZBTB41,LHX9,FAM151B,KCNN2,FIP1L1,KIT,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-145*:mirSVR_lowEffct hsa-miR-145*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-37 1.20E-33 1.38E-35 1.27E-34 93 1615 "SFTA3,LRRC43,BIRC6,ADORA1,NYNRIN,WDR35,BTF3,CD1D,CD1E,ZMYM5,CDK17,RGSL1,PDE4D,CHD1,CFAP54,HOMER1,SNCAIP,IL20,VCAN,FCRL5,ZNF586,SREK1,COG3,FBXL5,LOC439933,NUDT12,TBC1D4,OCIAD1,RABGAP1L,GNPDA2,DHFR,DNMT3A,RASA1,CLIP4,RNASEL,MBNL2,ELF1,LGR6,MARVELD2,DHRS2,TBC1D19,GP6,CWC27,SAP18,PCGF3,TNFRSF19,MROH9,SUPT20H,VEZT,SGCG,SLC30A6,ARHGEF40,SLC12A2,C1orf112,DCAF11,MEGF10,MYT1L,NMNAT2,NFASC,ANKLE2,ERBIN,ADGRL3,ADGRA3,ANO4,C5orf56,EML4,KMT5A,DOCK9,ZBTB49,GTF2H3,RASSF6,MAEL,NPL,HEXB,TECRL,SLAIN1,HSD17B4,WDR36,KCNT2,CENPH,CCDC169,FAM151B,TMEM178A,KCNJ9,CAB39L,KIF3C,DNAH10,LINC01913,SPRYD7,AXDND1,LMNB1,IFT88,LOX" MicroRNA hsa-miR-943:mirSVR_lowEffct hsa-miR-943:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-37 1.20E-33 1.38E-35 1.27E-34 86 1369 "NLN,CUL4A,RGS5,MSH2,NOP14,SLC4A4,CD84,MPZL1,CAST,FCGR2C,CD1D,UHMK1,SNTG2,CDK17,GLT1D1,SMIM14,THAP6,MPC2,PM20D1,POU2F1,HEATR5A,LYSMD3,LACC1,CSNK1G3,KIAA0040,PRKD1,FCRL5,DCAF8,COG3,DMXL1,TBC1D4,G3BP2,DHFR,PARPBP,DNMT3A,RAN,FAM129A,AASDH,FAM228A,MEMO1,CRYL1,SETDB2,RNASEL,MBNL2,MPHOSPH9,DRAM1,FAM81B,TLR6,USP44,SULT6B1,SUCO,SELP,FOXO1,FBXO11,NBEA,CCDC92,GFM2,N4BP2,GABRB1,CIDEB,PDS5B,TMEM183A,UHRF1BP1L,PPARGC1A,UTP20,LINC02393,PPIP5K2,ADGRL3,ADGRA3,ARHGEF28,EML4,DOCK9,TENT2,VRK2,ZNF10,IL6ST,PLB1,IRF1,LINC00272,PGAM5,CHPT1,KIF3C,KIR2DL1,KIR2DS4,AXDND1,ZNF304" MicroRNA hsa-miR-141*:mirSVR_highEffct hsa-miR-141*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-37 1.24E-33 1.40E-35 1.28E-34 84 1302 "RALGAPA1,ATP6V1G3,COG6,SNX24,ARHGEF7,NOVA1,CDKL2,CAST,NFXL1,CDK7,MRPL57,NRXN1,ATAD2B,ADGRF3,HOMER1,C1orf116,GNPTAB,EPGN,LYSMD3,NGDN,FCRL5,FCRL2,ZFYVE16,SREK1,COG3,PTPRC,SUPT7L,PARPBP,RB1,DTD2,RGS12,CLIP4,TXNDC15,GP6,ARSK,CWC27,DLEU1,PCGF3,UTP15,NDUFAF7,PIBF1,POLK,FMO1,VEZT,MBIP,UFM1,SLC22A4,LIMCH1,GABRA2,MRPS27,ERBIN,GJB2,UGT2A1,INSM2,PPIP5K2,METAP2,MTUS2,ADGRA3,ANO4,NCSTN,RNF17,CRB1,RASSF6,ATP6V0A2,ADAMTS19,UBE2K,HMGCR,TXK,GUF1,RXFP2,NSD2,ZNF10,KCNT2,MZF1,C12orf73,IL6ST,SPTSSA,TMEM178A,LMLN,KCNN2,TTC41P,DNAH10,RMST,LIG4" MicroRNA hsa-miR-338-3p:mirSVR_lowEffct hsa-miR-338-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-37 1.25E-33 1.40E-35 1.28E-34 101 1914 "TMEM132B,SEMA6A,SNX24,APC,BLZF1,ASTN1,ZNF542P,CADM3,CD84,CACNA1E,NRL,FCHO2,CD1E,SNTG2,CDK7,PCSK1,PDGFRA,CHD1,PFKFB2,ZNF595,NRXN1,SNX6,ATAD2B,ADGRF3,HECTD1,PTPRVP,CEP135,KIAA0040,FCRL2,ZNF586,ZFYVE16,SREK1,DMXL1,TBC1D4,PTPRC,OCIAD1,SUPT7L,LINC01257,PPP2R3C,NR1I3,RASA1,RGS12,SETDB2,PACRGL,RNASEL,EFNA5,SNORA53,KLHL12,STX2,DRAM1,CWC27,DLEU1,F10,FGF9,SDC1,FBXO11,MBIP,SCYL2,IVNS1ABP,SLC8A1,CCDC88A,CGREF1,DCAF11,GABRB1,KDM5B,NMNAT2,ZNF274,CD244,ATP8A2,NPAS3,NFASC,PPARGC1A,MAST4,ZNF544,ADAM17,PPIP5K2,ADGRA3,ANO4,DOCK9,RNF17,TFDP1,CRB1,BAZ1A,RASSF6,ACTR6,TPO,ADAMTS19,UBE2K,HMGCR,RXFP2,WDR36,FCRL6,ZNF470,PLB1,ZBTB41,LMLN,KIT,AMTN,TTC41P,AXDND1,LTA4H" MicroRNA hsa-miR-26a-2*:mirSVR_highEffct hsa-miR-26a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-37 1.49E-33 1.65E-35 1.51E-34 90 1512 "MAP1B,MDM4,KIAA1211,ANKRD34B,SNX24,SLC4A4,RAB29,CACNA1E,CHAMP1,CD1E,FCRLB,PCCA,PCDH9,FAM177A1,PDE4D,PFKFB2,WDFY2,SMIM14,ADGRF3,C1orf116,COPA,GNPTAB,SYCP3,LYSMD3,CEP135,FCRL5,DCAF8,MATR3,PIGG,PTGS2,DMXL1,FBXL5,CEP350,NUDT12,OCIAD1,PARPBP,TSEN15,FAM129A,TMEM161B,IPO4,DTD2,RGS4,RGS12,MEMO1,POLR1D,PACRGL,EFNA5,ELF1,PCOTH,CWC27,ADGRV1,FCGR3A,FCGR3B,MROH9,FBXO11,G2E3,BRMS1L,IVNS1ABP,SLC8A1,THADA,NR5A2,ZNF667,YPEL5,MYT1L,EAPP,OXGR1,RBKS,NEDD1,COMMD6,STRN,GJB2,MTUS2,C5orf56,DOCK9,COX18,NT5C1B,HEXB,TMEM174,VRK2,KCNT2,JCHAIN,PLB1,ANKS1B,FAM151B,AMTN,RNASE11,TTC41P,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-26b:mirSVR_lowEffct hsa-miR-26b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-37 1.55E-33 1.71E-35 1.56E-34 101 1919 "MAP1B,NLN,WDR35,PPFIA4,BLZF1,ARHGAP5,ARL1,STARD13,NOVA1,ODC1,FCHO2,ZNF664,FAM177A1,XPR1,PDGFRA,CENPC,RCBTB2,PFKFB2,SLC25A3,GPR180,MRPL57,SNX6,THAP6,HOMER1,AKAP6,POU2F1,SYCP3,PREPL,LACC1,IL20,ITSN2,DDX59,MATR3,KLHL3,NUDT12,OCIAD1,PTPRH,RABGAP1L,SUPT7L,GALNT14,TMEM161B,AASDH,REST,TMEM33,RNASEL,MBNL2,EIF2B1,ETF1,PCGF3,TNFRSF19,POLK,FOXO1,SUPT20H,ALKAL2,NUBPL,TADA1,SLC12A2,N4BP2,C1orf112,YPEL5,UGGT2,KIF21B,CENPJ,GJB6,OXGR1,KDM3B,CMPK2,LRCH1,KLHL20,PCDH17,GJA3,UGT2A1,SCFD1,PPIP5K2,ANO4,C5orf56,GPR12,ARHGEF28,KMT5C,RNF212,NPL,STARD4,NSD2,YTHDC2,IGF1,ZNF84,ZMYM2,ZBTB41,LHX9,TMEM178A,CAB39L,DIAPH3,KIR2DL1,KIR2DL4,KIR3DL1,KIR3DL2,AMTN,LETM1,AXDND1,LOX,MICU2" MicroRNA hsa-miR-623:mirSVR_lowEffct hsa-miR-623:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-37 1.65E-33 1.79E-35 1.64E-34 99 1844 "BIRC6,KIAA1211,SEMA6A,EP400,RGS5,ASTN1,CENPBD1P1,SLC4A4,ATP2B4,BCL2L2,BTF3,MPZL1,UHMK1,PCDH9,CDK18,PDGFRA,CFL2,CCDC122,PGGT1B,GPR180,CFAP54,PIK3C2B,CFAP45,UGT2B28,FAM53A,POU2F1,EPGN,CLOCK,DDX59,DCAF8,PIGG,KLHL3,OCIAD1,GNPDA2,PARPBP,C14orf119,FAM129A,TMEM161B,SMC6,OGFOD2,RGS12,CLIP4,SETDB2,PACRGL,DHRS2,GP6,ZNF219,CWC27,MAEA,ETF1,DLEU1,DNAJC27,ADGRV1,F10,N4BP2L2,PIBF1,POLK,SUCO,SDC1,FLT1,STAB2,SGCG,RUBCNL,NBEA,CCDC88A,PKD2L2,CYP1B1-AS1,GABRA2,MYT1L,CD244,ERAP1,HSPH1,SRP54,NFASC,ERBIN,TMED2,PPIP5K2,ANO4,C5orf56,RIPK3,ARHGEF28,DOCK9,AP4S1,ATP6V0A2,ADAMTS19,TECRL,WDR36,YTHDC2,JCHAIN,ZNF470,ZNF84,ZNF140,GALP,ANKS1B,ZMYM2,TMEM178A,TTC41P,SPRYD7,AXDND1" MicroRNA hsa-miR-301a:mirSVR_highEffct hsa-miR-301a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.34E-37 1.78E-33 1.91E-35 1.75E-34 93 1623 "RALGAPA1,MATN3,MDM4,BIRC6,KIAA1211,WDR35,APAF1,APC,BLZF1,ARL1,NCOA1,ATP12A,ZNF542P,STARD13,CD84,DAOA,CDKL2,CAST,RILPL1,SNTG2,PCDH9,FAM177A1,PDGFRA,CFL2,PFKFB2,GPR180,JAKMIP1,PTPRVP,HOMER1,RCHY1,FAM53A,GNPTAB,HEATR5A,LYSMD3,CLOCK,DNM3,PRKD1,FCRL2,DCAF8,ZFYVE16,MATR3,PTGS2,FBXL5,NUDT12,CEP120,PARPBP,RASA1,AASDH,MEMO1,ELK3,MPHOSPH9,SAP18,CLIP1,F10,GORAB,N4BP2L2,TNFRSF19,PIBF1,PEAR1,VEZT,NBEA,SLC8A1,CCDC88A,C1orf112,ZNF667,MEGF10,MYT1L,ERAP1,CMPK2,LRCH1,ERBIN,KLHL20,NPFFR2,INSM2,RNF17,ADAMTS19,TXK,UBC,SLAIN1,TENT2,C12orf73,ZMYM2,IRF1,CHPT1,LMLN,CAB39L,DIAPH3,TTC41P,DNAH10,RMST,NUAK2,LIG4,LMNB1" MicroRNA hsa-miR-589*:mirSVR_highEffct hsa-miR-589*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.26E-37 4.39E-33 4.68E-35 4.28E-34 99 1866 "MAP1B,ACOX3,HOMEZ,EP400,APC,NOP14,STARD13,SLC5A6,CCNA1,CAST,AMDHD1,CD1E,SLC5A8,PCDH9,PDE4D,RCBTB2,LTB4R,THAP6,STRN3,TAPT1,THTPA,EPGN,LYSMD3,SNCAIP,CEP135,FCRL5,ZFYVE16,SNX17,BIVM,PIGG,NUDT12,PTPRC,TINF2,PXMP2,PARPBP,RNF219,RAN,MBNL2,UGT2A3,FAM172A,ARSK,CWC27,ETF1,DLEU1,CLIP1,TRAPPC13,FNIP1,FGF9,SUCO,RUBCNL,FBXO11,BRMS1L,PKD2L2,SLC15A4,N4BP2,C1orf112,SLC22A4,NR5A2,YPEL5,CHFR,GABRA2,RAPGEF6,EAPP,IQGAP2,HSPH1,NPAS3,ANKLE2,SULT1E1,PPARGC1A,GJB2,TBC1D1,METAP2,ADGRL3,EML4,YIPF7,CRB1,TGFBI,ZBTB49,RASSF6,MAEL,HEXB,ADAMTS19,TXK,SLAIN1,HTR2A,STARD4,KCNT2,CCDC169,ZNF140,SDR39U1,KCNJ9,FIP1L1,EP400P1,MFSD2B,NUAK2,AXDND1,LMNB1,IFT88,PABPN1" MicroRNA hsa-miR-892b:mirSVR_lowEffct hsa-miR-892b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.54E-37 4.54E-33 4.78E-35 4.38E-34 92 1606 "MAP1B,MATN3,ADD1,SNX24,ASCL1,CENPBD1P1,ATP1A2,STARD13,KCTD12,MYH6,NFATC4,CACNA1E,MPZL1,PCDH9,DCLK1,RGSL1,PDE4D,PDGFRA,CHD1,ZNF595,CFAP54,LTB4R,GNPTAB,CLOCK,KIAA0040,EPS8L1,FBXL5,KLHL3,RABGAP1L,GNPDA2,EGLN3,B3GLCT,RASA1,REST,DTD2,SETDB2,PACRGL,MBNL2,DHRS2,DRAM1,MAEA,DLEU1,DNAJC27,ADGRV1,TRAPPC13,PCBD2,TOMM40L,FGF9,TNFRSF19,HSD17B7,RUBCNL,DDX51,POTEM,CGREF1,MEGF10,GABRA2,KIF21B,PDS5B,RAPGEF6,CENPJ,ZNF274,KDM3B,CMPK2,NFASC,DRC1,IKBIP,PCDH17,PSME4,ZNF544,ATP11A,PPIP5K2,ANO4,RIPK3,RNF212,C1QTNF9B,TDG,CRB1,AP4S1,ADAMTS19,GPN1,GUF1,HSD17B4,WDR36,MZF1,C12orf73,PLB1,ZBTB41,KCNN2,RMST,AXDND1,IFT88,PABPN1" MicroRNA hsa-miR-129-5p:mirSVR_highEffct hsa-miR-129-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.01E-36 5.37E-33 5.56E-35 5.09E-34 96 1757 "ADD1,COG6,WDR35,SEMA6A,RGS5,UVSSA,APC,CDKL4,FAM193A,NCOA1,CENPBD1P1,ATP2B4,CADM3,NFKBIA,LINC02347,CAMK4,FCHO2,PCDH9,GPR180,MRPL57,NRXN1,PITX1,THAP6,HOMER1,EPGN,LYSMD3,PREPL,VCAN,KIAA0040,FCRL5,NOS1AP,FCRL2,DDX59,ZFYVE16,MATR3,SPATA18,CEP350,PARPBP,DNMT3A,ATG10,RB1,ZNF329,DTD2,LAP3,EIF2D,TXNDC15,ELF1,MARVELD2,FAM172A,DEPDC4,ARSK,CWC27,ETF1,F10,TRAPPC13,GORAB,PIBF1,VEZT,ALKAL2,SLC30A6,THADA,CCDC88A,SLC22A4,YPEL5,LIMCH1,MYT1L,PDS5B,NMNAT2,JPH4,NAAA,ERAP1,RBKS,ANKLE2,ERBIN,PCDH17,COMMD6,NPFFR2,ADGRL3,YIPF7,TDG,CRB1,GPR161,ADAMTS19,KLF12,UBE2K,TECRL,SLAIN1,SPTSSA,ANKS1B,ZMYM2,IRF1,LHX9,FAM151B,NPHS2,CHPT1,DNAH10" MicroRNA hsa-miR-28-3p:mirSVR_lowEffct hsa-miR-28-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-36 5.39E-33 5.56E-35 5.09E-34 81 1228 "MAP1B,SMIM15,ADD1,NLN,SLAMF6,COG6,TBC1D14,WDR35,APBB2,RAD51AP2,ATP1A2,PPP1R12B,NOVA1,UHMK1,PCSK1,PFKFB2,CFAP45,AKAP6,STRN3,HEATR5A,FAM169A,DNM3,MPHOSPH8,MATR3,PTPRC,SLC35F6,C14orf119,RAN,RB1,TMEM161B,MEMO1,PACRGL,RNASEL,SPATA9,ELF1,ELK3,KLHL12,FAM172A,CWC27,DNAJC27,CLIP1,N4BP2L2,RELL1,POLK,RUBCNL,FBXO11,G2E3,BRMS1L,SLC30A6,SLC12A2,NR5A2,NMNAT2,ZNF274,CD244,PPARGC1A,GJA3,ZNF544,UGT2A1,ADGRL3,KMT5A,DOCK9,RNF212,CRB1,MSH6,BAZ1A,RAB2B,NPL,WDR36,STARD4,TPTE2,YTHDC2,IGF1,ZNF470,LHX9,FAM151B,NPHS2,KCNJ9,DNAH10,LCP1,AXDND1,LIG4" MicroRNA hsa-miR-105:mirSVR_highEffct hsa-miR-105:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-36 7.17E-33 7.31E-35 6.70E-34 87 1437 "RALGAPA1,ABL2,KIAA1211,EP400,DDX55,ARL1,NCOA1,STARD13,ARHGEF7,AMDHD1,ODC1,CHAMP1,LDB2,PCCA,PCDH9,PCK2,CFL2,ZNF595,TM9SF2,NRXN1,ATAD2B,POU2F1,LYSMD3,PREPL,BRI3BP,PRKD1,FCRL2,ZNF586,ZFYVE16,PTGS2,PTPRC,NR1H4,DNMT3A,SMC6,POLR1D,CRYL1,SETDB2,PACRGL,MBNL2,ELK3,LGR6,ARSK,CWC27,SAP18,ETF1,ABCA11P,CLIP1,SH3YL1,FNIP1,SELP,HSD17B7,FMO1,G2E3,NBEA,UFM1,TADA1,CCDC88A,SLC12A2,YPEL5,LIMCH1,GABRA2,GABRB1,HSPH1,SRP54,DRC1,RBKS,NEDD1,COMMD6,LPIN1,PPARGC1A,GJA3,MAST4,ATP11A,PPIP5K2,YIPF7,GTF3C2,MAEL,TPO,UBE2K,DCP2,CENPH,GALP,ZBED3-AS1,KIF2A,SPRYD7,CDK2AP1,SPATA13" MicroRNA hsa-miR-216b:mirSVR_highEffct hsa-miR-216b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.58E-36 8.38E-33 8.46E-35 7.75E-34 87 1440 "SFTA3,MDM4,NLN,COG6,CUL4A,APBB2,ASTN1,ATP1A2,NOVA1,DAOA,CACNA1E,CAST,CD1E,CDK17,PDE4D,CFL2,LINC01085,ATAD2B,BOD1L1,UGT2B28,THAP6,AKAP6,C12orf65,MATR3,BIVM,FBXL5,LOC439933,NUDT12,TBC1D4,CEP120,F11R,WDR1,PARPBP,RB1,TMEM161B,POLR1D,PACRGL,TXNDC15,MBNL2,TRAPPC12,LGR6,FAM172A,ETF1,DLEU1,UTP15,NDUFAF7,TNFRSF19,POLK,SUCO,SDC1,HSD17B7,VEZT,FBXO11,ALKAL2,PAICS,GFM2,ARHGEF40,MRPS14,GABRA2,GABRB1,KIF21B,ATP8A2,HSPH1,LRCH1,STRN,ZNF544,ADAM17,PPIP5K2,METAP2,ANO4,C5orf56,KMT5A,TDG,SLC7A8,TMPO,MAEL,NPL,HMGCR,UGT2B7,IL25,KCNT2,IRF1,FAM151B,FIP1L1,KIF3C,LTA4H,EEF1AKMT1" MicroRNA hsa-miR-145:mirSVR_lowEffct hsa-miR-145:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-36 8.51E-33 8.51E-35 7.79E-34 99 1881 "SMIM15,COG6,NYNRIN,TBC1D14,ZNF784,ARHGAP5,NOP14,FAM193A,SLC4A4,ADGRD1,CDKL2,MPZL1,RILPL1,FCGR2C,SCARB1,UHMK1,CENPC,CHD1,CCDC122,CFAP54,SNX6,PIK3C2B,ATAD2B,EPN1,HECTD1,POLE,FCRL5,BIVM,PIGG,SACS,GNPDA2,MTX3,LINC01257,PPP2R3C,C14orf119,DNMT3A,ATG10,RB1,REST,CLIP4,LRPPRC,TXNDC15,DCUN1D2,EIF2B1,ELF1,ARSK,STK32B,DLEU1,USP44,TMEM156,FCGR3A,FCGR3B,SPON2,SUCO,FBXO11,CCDC88A,ZNF605,SLC12A2,POTEM,SLC22A4,SLC22A5,EFR3B,GABRA2,NMNAT2,TMEM183A,UHRF1BP1L,ERAP1,CMPK2,SRP72,ZBTB37,GJA3,ARHGEF28,EML4,NT5C1B,CRB1,RASSF6,TMPO,GPN1,ARHGAP30,HMGCR,VRK2,STARD4,JCHAIN,ZFHX2,SELENOI,CCDC169,PLB1,ZMYM2,LINC00272,FAM151B,LMLN,KCNN2,CAB39L,KIF2A,DIAPH3,DNAH10,LCP1,NUAK2,EEF1AKMT1" MicroRNA hsa-miR-526a:mirSVR_lowEffct hsa-miR-526a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-36 9.09E-33 8.74E-35 8.00E-34 91 1584 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,CD1D,DCLK1,PCK2,RGSL1,PDGFRA,SMIM14,NUP37,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,NOS1AP,SREK1,NUDT12,G3BP2,RABGAP1L,SUPT7L,FAM129A,B3GLCT,TMEM161B,RGS4,POLR1D,ELK3,MARVELD2,TCTN2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,ATP8A2,SRP72,RBKS,IKBIP,NPFFR2,LPIN1,PPARGC1A,BRD8,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-518d-5p:mirSVR_lowEffct hsa-miR-518d-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-36 9.09E-33 8.74E-35 8.00E-34 91 1584 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,CD1D,DCLK1,PCK2,RGSL1,PDGFRA,SMIM14,NUP37,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,NOS1AP,SREK1,NUDT12,G3BP2,RABGAP1L,SUPT7L,FAM129A,B3GLCT,TMEM161B,RGS4,POLR1D,ELK3,MARVELD2,TCTN2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,ATP8A2,SRP72,RBKS,IKBIP,NPFFR2,LPIN1,PPARGC1A,BRD8,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-520c-5p:mirSVR_lowEffct hsa-miR-520c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-36 9.09E-33 8.74E-35 8.00E-34 91 1584 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,CD1D,DCLK1,PCK2,RGSL1,PDGFRA,SMIM14,NUP37,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,NOS1AP,SREK1,NUDT12,G3BP2,RABGAP1L,SUPT7L,FAM129A,B3GLCT,TMEM161B,RGS4,POLR1D,ELK3,MARVELD2,TCTN2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,ATP8A2,SRP72,RBKS,IKBIP,NPFFR2,LPIN1,PPARGC1A,BRD8,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-518f*:mirSVR_lowEffct hsa-miR-518f*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-36 9.09E-33 8.74E-35 8.00E-34 91 1584 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,CD1D,DCLK1,PCK2,RGSL1,PDGFRA,SMIM14,NUP37,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,NOS1AP,SREK1,NUDT12,G3BP2,RABGAP1L,SUPT7L,FAM129A,B3GLCT,TMEM161B,RGS4,POLR1D,ELK3,MARVELD2,TCTN2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,ATP8A2,SRP72,RBKS,IKBIP,NPFFR2,LPIN1,PPARGC1A,BRD8,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-31:mirSVR_lowEffct hsa-miR-31:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-36 9.30E-33 8.86E-35 8.11E-34 96 1769 "MAP1B,KIAA1211,TBC1D14,UVSSA,MSH2,ARL1,STXBP6,AACS,CENPBD1P1,ATP4B,NFATC4,SLC5A6,CACNA1E,CBLN3,NRL,CAMK4,TAF1B,MPZL1,UHMK1,PCDH9,DCLK1,XPR1,PDE6B,SNX6,BOD1L1,HECTD1,ANAPC4,STRN3,FAM53A,NCOR2,FAM169A,PRKD1,ZNF586,SNX17,SPATA18,COG3,DMXL1,FBXL5,CEP350,CEP120,DHFR,PARPBP,FAM129A,RNF31,TXNDC15,KIRREL1,DLEU1,SLC22A17,PCBD2,FGF9,SUCO,SDC1,G2E3,CCDC92,PLEKHA6,IVNS1ABP,THADA,PKD2L2,P2RX2,CGREF1,SLC22A5,YPEL5,GABRB1,PDS5B,EAPP,TMEM183A,ERAP1,HSPH1,NFASC,DRC1,ANKLE2,TCF7,RIPK3,STON1,KHNYN,XPO4,TDG,NCSTN,AP4S1,HSP90B1,UBE2K,RXFP2,TENT2,VRK2,PLB1,SPTSSA,LHX9,FAM49A,TMEM178A,KCNN2,CAB39L,KIF3C,MFSD2B,LINC01913,LINC00442,SPATA13" MicroRNA hsa-miR-654-3p:mirSVR_lowEffct hsa-miR-654-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-36 1.21E-32 1.14E-34 1.04E-33 99 1889 "RALGAPA1,SMIM15,MDM4,BIRC6,TMEM132B,WDR35,APC,CDKL4,BLZF1,ARL1,NOP14,NCOA1,ATP12A,ATP2B4,KCTD12,CADM3,PNP,ODC1,CHAMP1,CD1E,ZNF664,WDR66,PFKFB2,WDFY2,ITGBL1,PTPRVP,AKAP6,TAPT1,LYSMD3,PREPL,SNCAIP,ITSN2,KIAA0040,MATR3,COG3,CEP350,CEP120,PTPRC,GALNT14,EGLN3,RNF31,AASDH,RGS12,TXNDC15,LATS2,MBNL2,DCUN1D2,MPHOSPH9,EFS,SAP18,STK32B,DNAJC27,CLIP1,SLC22A17,ARL6IP4,UTP15,GORAB,POLK,PEAR1,GOLGA2P5,PAICS,SLC8A1,TMEM132D,UGGT2,LIMCH1,PDS5B,FAM114A1,IQGAP2,MRPS27,NFASC,GCKR,MCCC2,LRCH1,SULT1E1,LPIN1,MAST4,PSME4,ADAM17,PPIP5K2,METAP2,ANO4,ACSL6,GPR12,EML4,DOCK9,TFDP1,CRB1,MSH6,LINC01551,ZNF721,NPL,ADAMTS19,CCDC169,ANKS1B,CHPT1,CAB39L,KIF2A,SPRYD7,ZNF304" MicroRNA hsa-miR-216a:mirSVR_lowEffct hsa-miR-216a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-36 1.23E-32 1.15E-34 1.05E-33 100 1928 "MATN3,MCC,SMIM15,ADD1,COG6,WDR35,SNX24,MCFD2,UVSSA,APAF1,ASTN1,SLC4A4,ZNF542P,NLRP4,KCTD12,PROZ,LINC02347,DAOA,CBLN3,CDKL2,MPZL1,FCRLB,ZNF664,DCLK1,XPR1,PDGFRA,GLT1D1,RCBTB2,AKAP6,GNPTAB,LYSMD3,NGDN,SNCAIP,ITSN2,UBXN2A,NOS1AP,EPS8L1,KLHL3,PTPRC,F11R,SUPT7L,PARPBP,NR1H4,DNMT3A,B3GLCT,ATG10,ZNF329,PACRGL,DHRS2,TCTN2,DRAM1,ARSK,DNAJC27,USP44,PCBD2,FCAR,TOMM40L,TNFRSF19,POLK,SUCO,VEZT,NBEA,PLEKHA6,TADA1,CCDC88A,EFR3B,PDS5B,CENPJ,KDM3B,DRC1,MCCC2,LRCH1,PCDH17,LPIN1,PPIP5K2,C5orf56,ARHGEF28,DOCK9,KHNYN,XPO4,GRSF1,LINC01551,BAZ1A,TNR,ADAMTS19,TXK,UGT2B7,IL25,ZNF26,ZNF470,ZNF84,SELENOI,SPTSSA,ZBTB41,FAM151B,CAB39L,TTC41P,TTC7A,AXDND1,LTA4H" MicroRNA hsa-miR-183*:mirSVR_highEffct hsa-miR-183*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-36 1.68E-32 1.56E-34 1.43E-33 93 1670 "SFTA3,ABL2,MATN3,SMIM15,BIRC6,ADD1,NLN,MCFD2,BLZF1,ARHGAP5,ARL1,STARD13,KCTD12,LINC02347,NOVA1,PNP,NRL,RILPL1,FCHO2,SCARB1,NFXL1,PCSK1,CDK18,ZNF595,CFAP54,NRXN1,UGT2B28,AKAP6,CLOCK,PREPL,NCOR2,SNCAIP,LACC1,VCAN,CEP135,FCRL2,MATR3,LOC439933,CEP350,PTPRC,SACS,RABGAP1L,GNPDA2,SUPT7L,B3GLCT,SETDB2,EIF2D,MBNL2,MPHOSPH9,CWC27,ABCA11P,GORAB,SULT6B1,POLK,VEZT,ZCCHC8,MBIP,GFM2,IVNS1ABP,TADA1,CCDC88A,SLC12A2,N4BP2,SLC22A4,FSHR,PDS5B,CENPJ,ERAP1,ZBTB37,PSME4,TBC1D1,GOLGA3,ADGRL3,ADGRA3,C5orf56,RAB2B,TMPO,ZNF721,ZNF876P,TENT2,NSD2,ZNF26,KCNT2,IL6ST,ZNF140,LHX9,FAM151B,KIF3C,AMTN,RNASE11,AXDND1,LMNB1,LOX" MicroRNA hsa-miR-106a*:mirSVR_lowEffct hsa-miR-106a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.22E-36 1.71E-32 1.57E-34 1.44E-33 99 1897 "MATN3,KIAA1211,CUL4A,EP400,APC,MSH2,BLZF1,ATP4B,MYBPC1,STARD13,NFATC4,LINC02347,NOVA1,SNTG2,SLC5A8,PCDH9,CDK7,RCBTB2,PFKFB2,NRXN1,PIGR,PM20D1,LYSMD3,PREPL,SNCAIP,CSNK1G3,VCAN,ITSN2,DNM3,NOS1AP,SPATA18,CEP350,TBC1D4,PTPRC,SACS,G3BP2,WDR1,TSEN15,NR1H4,RASA1,ARGLU1,SMC6,AASDH,CLIP4,MEMO1,POLR1D,MPHOSPH9,LGR6,STX2,DNAJC27,GORAB,POLK,SUCO,FOXG1,FLT1,HSD17B7,SUPT20H,VEZT,RUBCNL,NBEA,NUBPL,UFM1,UGGT2,MYO16,MEGF10,GABRA2,TMEM183A,NPAS3,MCCC2,MIMT1,LPIN1,ANO4,GPR12,EML4,DOCK9,COX18,GRSF1,TGM1,MSH6,LINC01551,NPL,UBE2K,UBC,ZNF550,TENT2,VRK2,WDR36,TADA2B,C12orf73,PLB1,ANKS1B,CHPT1,KIF2A,DIAPH3,TTC41P,DNAH10,FAM71C,LIG4,MICU2" MicroRNA hsa-miR-18b:mirSVR_lowEffct hsa-miR-18b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.10E-36 2.18E-32 1.98E-34 1.81E-33 91 1602 "TMEM132B,SEMA6A,PPFIA4,BLZF1,ARHGAP5,FAM193A,ASTN1,ATP12A,ZNF542P,ATP4B,KCTD12,LINC02347,NOVA1,PNP,NRL,AMDHD1,MORN2,LDB2,RFLNA,PCDH9,CDK18,RGSL1,PIWIL1,PFKFB2,WDFY2,SNX6,PTPRVP,CLOCK,SNCAIP,C12orf65,FCRL5,DCAF8,PTPRC,EGLN3,RASA1,SMC6,DTD2,RGS4,RGS12,MBNL2,DRAM1,CLIP1,TRAPPC13,FCAR,NDUFAF7,GORAB,FGFR3,FLT1,STAB2,RUBCNL,G2E3,NBEA,DDX51,PLEKHA6,UFM1,TADA1,CCDC88A,SF3B6,YPEL5,ACIN1,CYP1B1-AS1,MYO16,GABRB1,ATP8A2,ANKLE2,LRCH1,STRN,TBC1D1,ADGRA3,RIPK3,CRB1,RAB2B,TMPO,ADAMTS19,UBE2K,GUF1,HTR2A,ZNF84,CCDC169,PLB1,SPTSSA,FAM49A,CHPT1,KCNN2,KIT,TTC41P,LETM1,FAM71C,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-942:mirSVR_highEffct hsa-miR-942:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.51E-36 2.40E-32 2.16E-34 1.98E-33 97 1828 "MDM4,ADD1,KIAA1211,ANKRD34B,CUL4A,SNX24,MCFD2,APC,DDX55,ARL1,ASCL1,CENPBD1P1,SLC4A4,LINC02347,NOVA1,CACNA1E,CBLN3,CAST,AMDHD1,PCDH9,CDK18,RGSL1,PDGFRA,PFKFB2,VIT,WDFY2,NRXN1,HECTD1,AKAP6,POU2F1,SNCAIP,LACC1,TTC37,ZNF586,ZFYVE16,MATR3,BIVM,SREK1,DCT,CEP350,GNPDA2,PARPBP,C14orf119,NR1H4,DNMT3A,EGLN3,SETDB2,GRTP1,SPATA9,KLHL12,MARVELD2,TBC1D19,DEPDC4,PCOTH,DNAJC27,ABCA11P,ELOVL7,NDUFAF7,LRRN2,TNFRSF19,PIBF1,FOXO1,VEZT,MBIP,SCYL2,THADA,ZNF605,SLC22A4,YPEL5,GABRB1,UHRF1BP1L,SRP72,NEDD1,IKBIP,KLHL20,PCDH17,MTUS2,ANO4,C5orf56,RIPK3,COP1,RNF17,TEP1,AP4S1,RASSF6,RIMBP2,ZNF721,ADAMTS19,STARD4,ZNF470,CCDC169,ANKS1B,FIP1L1,RNASE11,TTC41P,AXDND1,PABPN1" MicroRNA hsa-miR-2052:mirSVR_highEffct hsa-miR-2052:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.81E-36 2.56E-32 2.29E-34 2.09E-33 90 1569 "SMIM15,KIAA1211,SNX24,APAF1,DDX55,RAD51AP2,CD1D,PCCA,XPR1,PCSK1,CFL2,RCBTB2,PFKFB2,PGGT1B,NRXN1,BOD1L1,THAP6,HOMER1,AKAP6,STRN3,TAPT1,PM20D1,EPGN,LYSMD3,PREPL,CSNK1G3,LRRTM2,FAM169A,PRKD1,SPATA18,CEP120,PTPRC,F11R,RABGAP1L,PARPBP,TSEN15,DNMT3A,RNASEL,LGR6,DHRS2,MAEA,DNAJC27,CLIP1,ELOVL7,GORAB,FNIP1,SUCO,PEAR1,MROH9,VEZT,FBXO11,G2E3,BRMS1L,THADA,TADA1,PKD2L2,N4BP2,UGGT2,LIMCH1,UHRF1BP1L,HSPH1,CMPK2,MCCC2,IKBIP,PPARGC1A,STRN,GJB2,MAST4,TMED2,COP1,GRSF1,TGFBI,RAB2B,TMPO,ATP6V0A2,NPL,TECRL,HTR2A,STARD4,KCNT2,ANKS1B,ZMYM2,KCNN2,ANKDD1B,FIP1L1,EP400P1,RMST,LIG4,IFT88,LOX" MicroRNA hsa-miR-199a-5p:mirSVR_lowEffct hsa-miR-199a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.63E-36 2.99E-32 2.65E-34 2.43E-33 97 1833 "MAP1B,TMEM132B,ANKRD34B,COG6,NYNRIN,TBC1D14,SEMA6A,MCFD2,CENPBD1P1,STARD13,BCL2L2,CD84,ARHGEF7,AP1G2,NOVA1,MPZL1,PCCA,PDE4D,PDGFRA,CENPC,CHD1,PFKFB2,GPR180,ITGBL1,NCR1,HECTD1,AKAP6,POU2F1,LYSMD3,KIAA0040,PRKD1,FCRL5,DCAF8,LOC439933,COCH,F11R,TINF2,SUPT7L,SLC35F6,METTL11B,RB1,SLC9C2,CLIP4,EFNA5,GRTP1,SPATA9,MPHOSPH9,DHRS2,BORA,TBC1D19,ARSK,DLEU1,DNAJC27,TRAPPC13,IRF9,TOMM40L,TNFRSF19,RELL1,SUCO,STAB2,MBIP,THADA,SLC12A2,PKD2L2,WDCP,C1orf112,SLC22A4,UGGT2,MYO16,MEGF10,PDS5B,TMEM183A,ZNF274,CMPK2,ZBTB37,LPIN1,ADAM17,PPIP5K2,KMT5A,DOCK9,RNF17,GPR161,AP4S1,GZMB,RIMBP2,TNR,ADAMTS19,SLAIN1,NSD2,YTHDC2,ZNF26,PLB1,LMLN,DIAPH3,EP400P1,SPRYD7,LMNB1" MicroRNA hsa-miR-641:mirSVR_highEffct hsa-miR-641:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.91E-36 3.14E-32 2.76E-34 2.52E-33 100 1950 "RALGAPA1,MAP1B,SMIM15,BIRC6,KIAA1211,ANKRD34B,FBRSL1,FAM193A,ATP1A2,STARD13,CD84,DAOA,CAMK4,AMDHD1,ODC1,PCDH9,CDK17,VIT,GPR180,ITGBL1,NRXN1,NUP37,BOD1L1,THAP6,AKAP6,STRN3,EPGN,CSNK1G3,ZFYVE16,PIGG,SREK1,COG3,PTGS2,PTPRC,PARPBP,TSEN15,B3GLCT,TMEM161B,RGS4,SETDB2,LRPPRC,RNASEL,EFNA5,RNF4,ELF1,LGR6,TCTN2,FAM172A,ETF1,DNAJC27,PCGF3,CLIP1,USP44,UTP15,NDUFAF7,GORAB,FNIP1,FGF9,FOXG1,HSD17B7,FBXO11,NUBPL,SLC30A6,ARHGEF40,TADA1,SLC22A4,SLC22A5,MYT1L,KDM5B,OXGR1,NPAS3,SRP72,GCKR,MCCC2,ERBIN,KLHL20,PCDH17,BRD8,GOLGA3,ADGRL3,STON1,EML4,RNF17,BAZ1A,NPL,TXK,GUF1,PAPPA2,HTR2A,YTHDC2,ZNF26,KCNT2,SPTSSA,CHPT1,FIP1L1,KIT,RNASE11,NUAK2,LIG4,LMNB1" MicroRNA hsa-miR-153:mirSVR_lowEffct hsa-miR-153:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.01E-36 3.20E-32 2.78E-34 2.55E-33 91 1610 "MAP1B,BIRC6,ADD1,WDR35,FBRSL1,APBB2,ARHGAP5,NOP14,STARD13,DAOA,CDKL2,ODC1,FCHO2,LDB2,SCARB1,FAM177A1,PDE4D,CHD1,WDFY2,ITGBL1,CFAP54,ATAD2B,PKP1,ADGRF3,HOMER1,TAPT1,EPGN,LYSMD3,IL20,DNM3,EPS8L1,SREK1,DMXL1,NUDT12,SACS,SUPT7L,PARPBP,TSEN15,EGLN3,FAM129A,POLR1D,EFNA5,TXNDC15,MPHOSPH9,LGR6,SAP18,ELOVL7,N4BP2L2,RELL1,PIBF1,POLK,FOXO1,HSD17B7,FTLP10,VEZT,FBXO11,G2E3,BRMS1L,SLC8A1,ZNF605,C1orf112,ACIN1,LIMCH1,MYO16,NAAA,NPAS3,MRPS27,MCCC2,IKBIP,KLHL20,PPARGC1A,ZNF544,ATP11A,PPIP5K2,DOCK9,AP4S1,GTF3C2,RAB2B,PAPPA2,STARD4,YTHDC2,JCHAIN,ZNF84,ZMYM2,AMTN,RNASE11,AXDND1,LIG4,IFT88,LOX,SPATA13" MicroRNA hsa-miR-342-3p:mirSVR_lowEffct hsa-miR-342-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.85E-36 4.17E-32 3.58E-34 3.28E-33 98 1879 "MCC,SMIM15,BIRC6,NYNRIN,TBC1D14,PITPNM2,BLZF1,WDR19,NOP14,AACS,NCOA1,STARD13,CADM3,BCL2L2,LINC02347,PNP,NRL,MPZL1,RILPL1,FCHO2,CD1D,SCARB1,SNTG2,PCSK1,RGSL1,PDE4D,CENPC,CFL2,PFKFB2,VIT,DHRS1,ZNF595,WDFY2,SMIM14,PKP1,THAP6,C1orf116,TOGARAM2,IL20,C12orf65,DNM3,PRKD1,NOS1AP,IFT172,PSME1,NUDT12,RNF31,RB1,AASDH,RGS4,RNASEL,TXNDC15,STX2,DLEU1,DNAJC27,ADGRV1,PCBD2,FCGR2B,UTP15,N4BP2L2,SDC1,STAB2,FBXO11,ZNF605,CGREF1,SLC22A4,SLC22A5,MEGF10,GABRB1,PDS5B,NMNAT2,IQGAP2,ATP8A2,NFASC,PCDH17,COMMD6,NPFFR2,GJA3,PSME4,ATP11A,GOLGA3,ARHGEF28,KHNYN,CRB1,ADAMTS19,UBE2K,PAPPA2,WDR36,NSD2,ZMYM2,IRF1,CAB39L,KIF3C,KIT,EP400P1,RNASE11,LAD1,ZNF304" MicroRNA hsa-miR-3169:mirSVR_lowEffct hsa-miR-3169:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.92E-36 4.21E-32 3.58E-34 3.28E-33 94 1727 "RALGAPA1,NLN,SLAMF6,NYNRIN,CUL4A,EP400,UVSSA,MSH2,BLZF1,SLC4A4,BCL2L2,CD84,NFATC4,NOVA1,LDB2,CD1D,PCK2,CENPC,RCBTB2,CHD1,PFKFB2,PGGT1B,CFAP54,SMIM14,PIK3C2B,ADGRF3,POLN,THAP6,RCHY1,NOS1AP,DGKQ,PIGG,KLHL3,PTPRC,RABGAP1L,GNPDA2,GALNT14,EGLN3,SMC6,DTD2,MEMO1,NTN4,EIF2B1,KIRREL1,STK32B,DLEU1,ABCA11P,F10,PCBD2,TOMM40L,FLT1,STAB2,SUPT20H,SLC34A2,THADA,P2RX2,SLC22A5,EFR3B,ACIN1,LIMCH1,GABRB1,PDS5B,RAPGEF6,NPAS3,RBKS,PCDH17,MIMT1,GJB2,TBC1D1,ATP11A,PPIP5K2,ADGRL3,ANO4,GPR12,RNF212,NCSTN,ZBTB49,TMPO,MAEL,ATP6V0A2,ZNF876P,VRK2,WDR36,C12orf73,IL6ST,PLB1,SDR39U1,LHX9,CAB39L,SLAMF9,LAD1,LETM1,TTC7A,IFT88" MicroRNA hsa-miR-548b-3p:mirSVR_lowEffct hsa-miR-548b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.95E-36 4.23E-32 3.58E-34 3.28E-33 100 1957 "RALGAPA1,SFTA3,ACOX3,BLZF1,ATP1A2,CCDC181,ATP7B,BTF3,SLC5A6,NRL,MPZL1,FCHO2,CHAMP1,NFXL1,PCDH9,PCSK1,PDE4D,MPC2,GNPTAB,SNCAIP,CEP135,PIGG,SREK1,CEP350,OCIAD1,F11R,RABGAP1L,DTD2,LAP3,TMEM33,CRYL1,MBNL2,DCUN1D2,KLHL12,DHRS2,EFS,STK32B,ADGRV1,ARL6IP4,FCAR,GORAB,FGF9,SUCO,RASA3,VEZT,RUBCNL,FBXO11,PAICS,SLC30A6,TADA1,PKD2L2,NR5A2,LIMCH1,MYO16,MEGF10,GABRA2,PDS5B,KDM5B,NMNAT2,TMEM183A,ERAP1,KDM3B,CMPK2,RBKS,MCCC2,IKBIP,PCDH17,GJA3,PPIP5K2,ANO4,GPR12,GPR18,STON1,DOCK9,RNF212,FZD10,RIMBP2,MAEL,ATP6V0A2,ADAMTS19,UBE2K,HMGCR,TXK,SLAIN1,HSD17B4,TENT2,NSD2,TPTE2,FCRL6,IGF1,IL6ST,PLB1,SPTSSA,ZBTB41,KCNN2,RNASE11,LINC01913,LCP1,SPRYD7,LMNB1" MicroRNA hsa-miR-1272:mirSVR_lowEffct hsa-miR-1272:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.29E-36 4.41E-32 3.70E-34 3.39E-33 99 1919 "MAP1B,BIRC6,NLN,WDR35,SEMA6A,HOMEZ,UVSSA,ATP1A2,SLC4A4,BCL2L2,NEDD8,ARHGEF7,LINC02347,TAF1B,MPZL1,PAH,DCLK1,XPR1,CDK17,CHD1,ITGBL1,TM9SF2,ATAD2B,PTPRVP,THAP6,C1orf116,STRN3,TAPT1,HEATR5A,SNCAIP,UBXN2A,FCRL5,ZNF586,G3BP2,RABGAP1L,GNPDA2,LINC01257,RASA1,LRPPRC,RNASE2,PACRGL,MBNL2,DCUN1D2,UGT2A3,STX2,GP6,FAM81B,DNAJC27,ADGRV1,F10,ELOVL7,USP44,TOMM40L,PIBF1,SUCO,MROH9,FLT1,FLT3,FBXO11,G2E3,SLC8A1,SLC12A2,SLC22A4,LIMCH1,CYP1B1-AS1,MEGF10,ATP8A2,OXGR1,GC,PPARGC1A,GJA3,PSME4,PPIP5K2,ARHGEF28,KHNYN,TFDP1,AP4S1,GTF2H3,RAB2B,RIMBP2,HEXB,HSP90B1,SLAIN1,WDR36,DCP2,TADA2B,ZNF470,ZNF84,IL6ST,CCDC190,CHPT1,KCNN2,CAB39L,KIT,LAD1,NUAK2,TTC7A,LMNB1,SKA3" MicroRNA hsa-miR-362-5p:mirSVR_lowEffct hsa-miR-362-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.65E-36 4.60E-32 3.83E-34 3.51E-33 100 1959 "MDM4,ANKRD34B,COG6,NYNRIN,SNX24,MSH2,DDX55,ZNF784,NOP14,NCOA1,ATP2B4,B4GALT3,BTF3,NOVA1,MPZL1,ZMYM5,PDGFRA,PDE6B,CHD1,VIT,EPGN,LYSMD3,BRI3BP,FAM169A,MPHOSPH8,NOS1AP,FCRL2,DCAF8,IFT172,MATR3,BIVM,SREK1,TBC1D4,PTPRC,PPP2R3C,DNMT3A,FAM129A,TMEM161B,SLC9C2,LAP3,TXNDC15,MBNL2,ELK3,MARVELD2,TCTN2,BORA,TBC1D19,ETF1,ABCA11P,SLC22A17,PCBD2,FCAR,PIBF1,POLK,FLT1,FTLP10,TM9SF1,CCDC88A,PKD2L2,SLC15A4,C1orf112,UGGT2,SNRPF,KIF21B,NMNAT2,NAAA,MCCC2,NEDD1,IKBIP,LPIN1,UTP20,C5orf56,GPR12,EML4,KMT5A,COX18,TFDP1,CRB1,AP4S1,BAZ1A,ACTR6,RIMBP2,MAEL,SLAIN1,HSD17B4,PAPPA2,VRK2,WDR36,TADA2B,ZNF470,ANKS1B,FAM151B,CHPT1,DIAPH3,LAD1,LCP1,AXDND1,IFT88,MICU2,SPATA13" MicroRNA hsa-miR-96*:mirSVR_lowEffct hsa-miR-96*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-35 5.60E-32 4.63E-34 4.24E-33 95 1771 "RALGAPA1,SFTA3,MAP1B,ADD1,NLN,APC,ASTN1,ZNF542P,KCTD12,PROZ,LINC02347,CAMK4,ZNF664,DCLK1,GPR180,CFAP54,LINC01085,ATAD2B,THAP6,AKAP6,STRN3,MPC2,TOGARAM2,CRHBP,SNCAIP,IL20,VCAN,LRRTM2,CEP135,FCRL5,DDX59,ZNF586,TBC1D4,GNPDA2,WDR1,PARPBP,C14orf119,TSEN15,DNMT3A,ATG10,RB1,ZNF329,RGS4,RNASEL,MBNL2,LGR6,BORA,STX2,FAM172A,PCGF3,ELOVL7,TMEM129,RELL1,TACC3,FOXG1,MROH9,FLT3,STAB2,BRMS1L,UFM1,THADA,CCDC88A,C1orf112,MYO16,MEGF10,PDS5B,CD244,ERAP1,SRP54,SRP72,ERBIN,KLHL20,PPARGC1A,MTUS2,GOLGA3,ANO4,TCF7,ARHGEF28,DOCK9,COX18,HAL,ATP6V0A2,KLF12,GPN1,VRK2,WDR36,NSD2,KCNT2,FAM151B,LMLN,LINC01913,RMST,SPRYD7,LMNB1,ZNF304" MicroRNA hsa-miR-448:mirSVR_highEffct hsa-miR-448:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.17E-35 6.23E-32 5.11E-34 4.68E-33 91 1624 "RALGAPA1,MATN3,ADD1,CUL4A,NCOA1,ATP2B4,STARD13,KCTD12,NOVA1,MPZL1,CAST,SCARB1,SLC5A8,PCDH9,ZMYM5,PDE4D,PDGFRA,CFL2,ZNF595,SMIM14,ATAD2B,THAP6,HOMER1,EPGN,CEP135,DNM3,FCRL5,ZFYVE16,COG3,DMXL1,CEP350,NUDT12,COCH,TBC1D4,PTPRC,PTPRH,DHFR,TSEN15,NR1H4,DTD2,SLC9C2,CLIP4,ZNF419,SETDB2,MBNL2,ELF1,TBC1D19,ABCA11P,SH3YL1,NDUFAF7,N4BP2L2,FGF9,SUCO,FLT1,HSD17B7,G2E3,NBEA,BRMS1L,IVNS1ABP,SLC12A2,YPEL5,LIMCH1,RAPGEF6,NAAA,NPAS3,LRCH1,IKBIP,COMMD6,ATP11A,PPIP5K2,METAP2,ANO4,DOCK9,FCRLA,CRB1,ZBTB49,RASSF6,RAB2B,ZNF721,NPL,GUF1,TPTE2,YTHDC2,JCHAIN,C12orf73,ZMYM2,ZBED3-AS1,AMTN,AXDND1,IFT88,LOX" MicroRNA hsa-miR-1270:mirSVR_lowEffct hsa-miR-1270:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-35 6.99E-32 5.68E-34 5.20E-33 96 1814 "MCC,MDM4,KIAA1211,COG6,WDR35,SEMA6A,RGS5,MSH2,ARHGAP5,ARL1,ASTN1,CD84,BTF3,CCNA1,RAB29,NOVA1,RILPL1,RGSL1,PDE4D,PDGFRA,PFKFB2,HECTD1,PTPRVP,THAP6,STRN3,TOGARAM2,POU2F1,CLOCK,PREPL,SNCAIP,DNM3,UBXN2A,PRKD1,ZNF586,SNX17,LOC439933,TBC1D4,PTPRC,OCIAD1,FAM129A,B3GLCT,OGFOD2,GUSBP3,STK32B,PCGF3,SLC22A17,ELOVL7,TRAPPC13,PCBD2,FCGR3A,FGF9,RELL1,PIBF1,SUCO,FOXO1,FLT1,HSD17B7,FMO1,FTLP10,RUBCNL,BRMS1L,ZNF667,CIDEB,UHRF1BP1L,ERAP1,ATP8A2,KDM3B,MCCC2,GJA3,BRD8,ZNF544,TMED2,GOLGA3,ARHGEF28,COX18,FZD10,RIMBP2,MAEL,HAL,NPL,TPO,ARHGAP30,TECRL,WDR36,ZNF10,JCHAIN,CCDC169,FAM151B,NPHS2,KCNJ9,KCNN2,KIR2DL4,TTC41P,LINC01913,LCP1,NUAK2" MicroRNA hsa-miR-660:mirSVR_lowEffct hsa-miR-660:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-35 8.13E-32 6.55E-34 6.00E-33 81 1276 "BIRC6,ANKRD34B,NYNRIN,MCFD2,PPFIA4,APC,BLZF1,ARL1,CD84,ARHGEF7,MPZL1,AMDHD1,CHAMP1,SCARB1,SLC5A8,DCLK1,RGSL1,PDGFRA,CHD1,ITGBL1,CFAP54,BOD1L1,AKAP6,TOGARAM2,NGDN,CSNK1G3,CEP135,DCAF8,BIVM,EPS8L1,CEP350,GNPDA2,PARPBP,TMEM161B,AASDH,CLIP4,ELF1,BORA,ABCA11P,CLIP1,NDUFAF7,TNFRSF19,RELL1,POLK,SUCO,FLT1,SFSWAP,GOLGA2P5,NUBPL,THADA,CCDC88A,PKD2L2,TMEM132D,UGGT2,GABRA2,MYT1L,KIF21B,CD244,MIMT1,MAST4,INSM2,TMED2,EML4,COP1,TFDP1,GTF3C2,TMPO,MAEL,ADAMTS19,SLAIN1,WDR36,YTHDC2,SPTSSA,ANKS1B,ZBTB41,LMLN,AMTN,MFSD2B,RMST,SPRYD7,AXDND1" MicroRNA hsa-miR-299-5p:mirSVR_lowEffct hsa-miR-299-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-35 8.38E-32 6.71E-34 6.14E-33 88 1521 "BIRC6,SEMA6A,SNX24,APC,ARHGAP5,ATP2B4,ATP4B,BTF3,NOVA1,CAST,LDB2,ZNF664,ZMYM5,CDK7,PDGFRA,PDE6B,PIWIL1,CHD1,SLC25A3,TM9SF2,SNX6,JAKMIP1,STRN3,MPC2,SNCAIP,MPHOSPH8,PRKD1,FCRL5,SPATA18,PTGS2,DMXL1,NUDT12,GNPDA2,WDR1,PPP2R3C,B3GLCT,CLIP4,NTN4,TXNDC15,MBNL2,MARVELD2,TBC1D19,GP6,FAM172A,ARSK,FAM81B,CWC27,PCGF3,N4BP2L2,POLK,FMO1,STAB2,SLC34A2,FBXO11,BRMS1L,GFM2,SCYL2,IVNS1ABP,SLC8A1,SLC12A2,SLC15A4,WDCP,ZNF667,YPEL5,MYO16,PDS5B,RAPGEF6,ERAP1,ATP8A2,IKBIP,KLHL20,BRD8,ADGRL3,RIPK3,BAZ1A,NPL,HMGCR,TENT2,VRK2,NSD2,ZNF84,ANKS1B,LHX9,ZBED3-AS1,LINC00442,LETM1,AXDND1,LIG4" MicroRNA hsa-miR-197:mirSVR_lowEffct hsa-miR-197:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-35 9.09E-32 7.21E-34 6.60E-33 91 1632 "IL17D,LRRC43,MDM4,ATP6V1G3,SEMA6A,MSH2,DDX55,FAM193A,AACS,B4GALT3,PNP,DAOA,MPZL1,FCGR2C,CD1D,SCFD2,CDK17,CENPC,GLT1D1,RCBTB2,DHRS1,MRPL57,PIK3C2B,PKP1,AKAP6,LRRTM2,DCAF8,DGKQ,PIGG,LOC439933,KLHL3,PTPRC,SACS,PPP2R3C,RB1,ARGLU1,FAM228A,MARVELD2,PCGF3,PCBD2,TOMM40L,FGF9,VEZT,FBXO11,NBEA,DDX51,PLEKHA6,NUBPL,TADA1,SLC12A2,TMEM132D,C1orf112,SLC22A4,SLC22A5,ZNF667,YPEL5,EFR3B,UGGT2,LIMCH1,DCAF11,MYO16,NPAS3,MRPS27,MCCC2,LILRB4,ACSL6,C5orf56,COP1,TDG,NT5C1B,SLC7A8,AP4S1,BAZ1A,NPL,ADAMTS19,LTB4R2,HPCAL1,YTHDC2,C12orf73,ZMYM2,TDRD3,ZBED3-AS1,CHPT1,KCNJ9,ANKDD1B,AMTN,LINC01913,LETM1,TTC7A,IFT88,LTA4H" MicroRNA hsa-miR-522:mirSVR_highEffct hsa-miR-522:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-35 1.20E-31 9.43E-34 8.64E-33 92 1675 "RALGAPA1,KIAA1211,NYNRIN,ARHGAP5,ASCL1,KCTD12,RAB29,NOVA1,DAOA,UHMK1,PDE4D,PDGFRA,CENPC,RCBTB2,ITGBL1,PIGR,ATAD2B,HOMER1,AKAP6,MPC2,TAPT1,SNCAIP,VCAN,MATR3,NUDT12,GNPDA2,DHFR,FAM129A,B3GLCT,RASA1,FAM228A,SLC9C2,MPHOSPH9,ZNF671,DEPDC4,ARSK,ETF1,ADGRV1,CLIP1,USP44,NDUFAF7,FNIP1,RELL1,PIBF1,SUCO,FLT1,RASA3,VEZT,ZCCHC8,RUBCNL,G2E3,NBEA,TADA1,CCDC88A,SLC22A4,DCAF11,GABRB1,FAM114A1,NMNAT2,RAPGEF6,CENPJ,NAAA,ATP8A2,HSPH1,CMPK2,PCDH17,COMMD6,NPFFR2,PPARGC1A,GJB2,ZNF544,INSM2,TMED2,PPIP5K2,STON1,TEP1,LINC01551,HAL,HSP90B1,HTR2A,WDR36,YTHDC2,KCNT2,C12orf73,CCDC169,FAM151B,TMEM178A,KIT,TTC41P,DNAH10,RMST,AXDND1" MicroRNA hsa-miR-101*:mirSVR_lowEffct hsa-miR-101*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.42E-35 1.29E-31 1.01E-33 9.22E-33 93 1714 "KIAA1211,ANKRD34B,COG6,CUL4A,EP400,BLZF1,LINC02347,NOVA1,PNP,SNTG2,PCDH9,DCLK1,CDK17,PDGFRA,PFKFB2,PIK3C2B,POU2F1,LYSMD3,CLOCK,CRHBP,SNCAIP,VCAN,DNM3,FCRL5,NOS1AP,COG3,CEP120,PTPRC,C14orf119,TSEN15,RAN,EGLN3,TMEM161B,DTD2,SETDB2,TXNDC15,ELF1,ELK3,LGR6,BORA,CWC27,PCGF3,USP44,SULT6B1,FNIP1,POLK,FOXG1,RASA3,VEZT,FBXO11,G2E3,BRMS1L,NUBPL,SCYL2,IVNS1ABP,SLC12A2,SLC15A4,UGGT2,LIMCH1,MYO16,GABRA2,PDS5B,NMNAT2,RAPGEF6,ZNF274,CD244,NPAS3,CMPK2,LILRB1,KLHL20,PPARGC1A,ATP11A,PPIP5K2,ADGRL3,ARHGEF28,STON1,C1QTNF9B,TEP1,ZNF550,SLAIN1,TENT2,VRK2,HTR2A,NSD2,FCRL6,KCNT2,TADA2B,ZBTB41,KIR2DL1,LINC00442,ZDHHC20,IFT88,ZNF304" MicroRNA hsa-miR-152:mirSVR_lowEffct hsa-miR-152:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.93E-35 1.56E-31 1.21E-33 1.11E-32 95 1794 "MDM4,BIRC6,ATP6V1G3,ANKRD34B,HOMEZ,ZNF784,AACS,ASTN1,CENPBD1P1,ATP12A,ZNF542P,NLRP4,ATP2B4,BCL2L2,NFATC4,CCNA1,AP1G2,NOVA1,SYT2,FCHO2,UHMK1,SNTG2,RGSL1,PDE4D,PDGFRA,TAPT1,HEATR5A,DNM3,PRKD1,FCRL2,ZNF586,DCAF8,EPS8L1,PIGG,PTGS2,CEP350,G3BP2,GNPDA2,RNF31,LAP3,MEMO1,NTN4,LRPPRC,ELK3,MPHOSPH9,STX2,EFS,SAP18,ETF1,DLEU1,CLIP1,FCAR,SPON2,RELL1,SUPT20H,RASA3,ZCCHC8,NBEA,SLC30A6,IVNS1ABP,SLC8A1,CCDC88A,ZNF605,POTEM,SLC15A4,CGREF1,WDCP,SLC22A5,MYO16,GABRB1,ERBIN,LPIN1,MAST4,ZNF544,ADAM17,TCF7,DOCK9,C1QTNF9B,XPO4,RNF17,TFDP1,RAB2B,HSP90B1,UBE2K,GPN1,RXFP2,SLAIN1,ZNF876P,PAPPA2,IGF1,SDR39U1,LHX9,FAM151B,DIAPH3,LINC00442" MicroRNA hsa-miR-606:mirSVR_highEffct hsa-miR-606:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.74E-35 1.99E-31 1.53E-33 1.40E-32 76 1126 "RALGAPA1,SFTA3,IL17D,EP400,SNX24,APC,BLZF1,ARL1,CCNA1,AMDHD1,FCHO2,CD1E,PAH,PDGFRA,CENPC,CFL2,GPR180,COLEC11,SNX6,BOD1L1,HOMER1,GNPTAB,THTPA,LYSMD3,CRHBP,CSNK1G3,CEP135,PRKD1,MATR3,BIVM,PTGS2,DMXL1,DHX9,NUDT12,OCIAD1,TINF2,SACS,SLC9C2,PACRGL,RNF4,MBNL2,MPHOSPH9,TBC1D19,ABCA11P,UTP15,NDUFAF7,N4BP2L2,PIBF1,POLK,VEZT,UFM1,SCYL2,THADA,TADA1,CCDC88A,C1orf112,PDS5B,RAPGEF6,SRP54,LRCH1,IKBIP,PPARGC1A,UTP20,MTUS2,ARHGEF28,TDG,RAB2B,FZD10,ZNF721,GUF1,STARD4,YTHDC2,ZNF140,SPTSSA,NUAK2,CDK2AP1" MicroRNA hsa-miR-653:mirSVR_lowEffct hsa-miR-653:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-35 2.30E-31 1.76E-33 1.61E-32 97 1880 "MDM4,RGS5,MCFD2,APBB2,MSH2,ATP12A,SLC4A4,KCTD12,SLC5A6,NFKBIA,CCNA1,PCDH9,DCLK1,ZMYM5,PDE4D,GLT1D1,WDFY2,UGT2B28,PTPRVP,HOMER1,AKAP6,MPC2,RCHY1,GNPTAB,EPGN,NCOR2,CSNK1G3,ITSN2,UBXN2A,PRKD1,IFT172,MATR3,SNX17,KLHL3,COCH,SACS,MTX3,LINC01257,PARPBP,RNF219,FAM129A,RASA1,SLC9C2,TMEM33,MEMO1,SETDB2,PACRGL,ELF1,DRAM1,DNAJC27,SLC22A17,TOMM40L,VEZT,RUBCNL,DDX51,BRMS1L,PAICS,UFM1,GFM2,SCYL2,SLC8A1,C1orf112,MYO16,KIF21B,NMNAT2,JPH4,CD244,NFASC,MCCC2,ZBTB37,UGT2A1,PPIP5K2,DOCK9,RNF17,TFDP1,CRB1,GTF2H3,RIMBP2,MAEL,NPL,ADAMTS19,GUF1,UBC,SLAIN1,NSD2,KCNT2,ZNF470,SPTSSA,ANKS1B,ZMYM2,ZBED3-AS1,CHPT1,KCNN2,FIP1L1,RNASE11,TTC41P,LMNB1" MicroRNA hsa-miR-433:mirSVR_lowEffct hsa-miR-433:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-35 2.33E-31 1.77E-33 1.62E-32 94 1765 "MATN3,TMEM132B,ANKRD34B,SEMA6A,RGS5,MSH2,SLC4A4,FCRL3,NOVA1,AMDHD1,CHAMP1,RGSL1,PDGFRA,CFL2,PFKFB2,VIT,ZNF595,ITGBL1,CFAP54,HECTD1,HOMER1,C1orf116,DNM3,ZNF586,SNX17,DMXL1,FBXL5,LOC439933,GNPDA2,MTX3,DNMT3A,FAM129A,RASA1,TMEM33,NTN4,UGT2A3,MPHOSPH9,SAP18,F10,TRAPPC13,FCGR2B,FCGR3A,FCGR3B,N4BP2L2,FGF9,POLK,FOXG1,FMO1,SFSWAP,TMEM175,NBEA,UFM1,SLC30A6,ZNF605,POTEM,P2RX2,C1orf112,NR5A2,MEGF10,GABRA2,NMNAT2,TMEM183A,UHRF1BP1L,ATP8A2,KDM3B,KLHL20,SULT1E1,LPIN1,MAST4,UTP20,ATP11A,ADGRA3,LILRB4,ACSL6,STON1,RNF17,NT5C1B,CRB1,BAZ1A,NPL,HEXB,ADAMTS19,SLAIN1,WDR36,YTHDC2,IGF1,SPTSSA,TMEM178A,KCNN2,ANKDD1B,SLAMF9,LCP1,LIG4,IFT88" MicroRNA hsa-miR-3074:mirSVR_highEffct hsa-miR-3074:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.55E-35 2.42E-31 1.82E-33 1.67E-32 75 1097 "RALGAPA1,MDM4,ADORA1,NLN,ANKRD34B,BLZF1,STXBP6,SLC4A4,ATP2B4,ATP4B,ATP7B,NFATC4,ARHGEF7,DAOA,CDKL2,PCCA,PDE4D,CENPC,GLT1D1,CFL2,ZNF595,SLC25A3,NRXN1,SMIM14,HOMER1,AKAP6,STRN3,TAPT1,COPA,RCHY1,OCIAD1,G3BP2,GNPDA2,EGLN3,RB1,SLC9C2,CLIP4,NTN4,RNF4,UGT2A3,ADGRV1,TRAPPC13,NDUFAF7,GORAB,PIBF1,SUCO,SUPT20H,SFSWAP,SLC8A1,PDS5B,RAPGEF6,EAPP,ZNF274,ANKLE2,LRCH1,CFHR4,SULT1E1,LPIN1,PPARGC1A,ZNF544,ACSL6,EML4,NT5C1B,MSH6,AP4S1,GTF2H3,BAZ1A,HAL,NPL,HSP90B1,TMEM174,CCDC169,KCNN2,DIAPH3,RILPL2" MicroRNA hsa-miR-16-1*:mirSVR_lowEffct hsa-miR-16-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.67E-35 2.48E-31 1.85E-33 1.70E-32 99 1960 "LRRC43,SEMA6A,SNX24,MCFD2,ARHGAP5,ARL1,NCOA1,CCDC181,MYBPC1,B4GALT3,RAB29,NOVA1,MPZL1,CAST,PCCA,CDK7,PDE4D,CENPC,RCBTB2,CHD1,PFKFB2,PGGT1B,CFAP54,PIK3C2B,ATAD2B,THAP6,POLE,VCAN,LRRTM2,DNM3,ZFYVE16,BIVM,DMXL1,LOC439933,KLHL3,PARPBP,FAM129A,TMEM33,POLR1D,UGT2A3,ELF1,ELK3,MARVELD2,TBC1D19,FAM172A,PCBD2,SULT6B1,POLK,FOXO1,VEZT,ZCCHC8,UFM1,IVNS1ABP,THADA,ARHGEF40,CCDC88A,PKD2L2,N4BP2,C1orf112,SF3B6,NR5A2,ZNF667,CHFR,LIMCH1,MEGF10,KIF21B,NAAA,UHRF1BP1L,KDM3B,IKBIP,SULT1E1,GJA3,STRN,ATP11A,MTUS2,ADGRL3,ANO4,DOCK9,C1QTNF9B,COX18,RNF17,NT5C1B,ZBTB49,RASSF6,TMPO,ADAMTS19,HSD17B4,WDR36,IGF1,TADA2B,ZNF470,ZNF84,ZBTB41,FAM49A,CHPT1,CAB39L,DNAH10,ZDHHC20,SPATA13" MicroRNA hsa-miR-1224-5p:mirSVR_lowEffct hsa-miR-1224-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.77E-35 2.54E-31 1.88E-33 1.72E-32 91 1654 "NDRG2,ADORA1,SLAMF6,CUL4A,MCFD2,WDR19,FAM193A,ATP1A2,ATP12A,SLC4A4,NRL,SCARB1,PCDH9,DCLK1,XPR1,CDK17,RGSL1,CHD1,WDFY2,PIGR,AKAP6,TAPT1,RCHY1,UBXN2A,FCRL5,CTSG,BIVM,PIGG,PTPRC,GNPDA2,PPP2R3C,RNF219,NR1I3,EGLN3,FAM129A,RGS4,RGS12,POLR1D,PACRGL,DCUN1D2,KIRREL1,STK32B,MAEA,DLEU1,F7,FCAR,POLK,FOXO1,GOLGA2P5,TMEM175,SLC34A2,MBIP,PKD2L2,TMEM132D,CGREF1,PDS5B,ZNF274,ATP8A2,NFASC,KLHL20,CFHR4,ZNF544,GOLGA3,ADGRA3,ANO4,C5orf56,RNF212,CRB1,SLC7A8,LINC01551,GTF2H3,NPL,HSP90B1,ZNF876P,WDR36,DCP2,FCRL6,ZNF10,IL6ST,PLB1,CCDC190,ZBTB41,NPHS2,ZBED3-AS1,TMEM178A,KCNJ9,LMLN,DIAPH3,TTC41P,AXDND1,ZNF304" MicroRNA hsa-miR-3146:mirSVR_lowEffct hsa-miR-3146:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-35 2.56E-31 1.88E-33 1.72E-32 81 1297 "MDM4,SLAMF6,COG6,CUL4A,EP400,MCFD2,CDKL4,ZNF784,SLC4A4,ZNF542P,ATP2B4,STARD13,NOVA1,PNP,CACNA1E,PCCA,PCDH9,ZMYM5,CDK17,WDFY2,NRXN1,PIK3C2B,THAP6,STRN3,RCHY1,CRHBP,BRI3BP,CSNK1G3,FAM169A,DNM3,UBXN2A,FCRL5,SNX17,COG3,DMXL1,TBC1D4,PTPRC,SUPT7L,RNF219,NR1I3,DTD2,RGS12,RNASEL,EFNA5,LATS2,DCUN1D2,ELK3,STX2,FAM172A,DRAM1,TRAPPC13,RUBCNL,PLEKHA6,SLC30A6,SCYL2,CCDC88A,WDCP,MRPS14,LIMCH1,GABRA2,EAPP,NPAS3,MRPS27,RBKS,LRCH1,GJA3,GJB2,ZNF544,TBC1D1,ACSL6,STON1,TEP1,ZBTB49,RASSF6,NPL,GUF1,HSD17B4,MZF1,LHX9,KIF2A,AXDND1" MicroRNA hsa-miR-515-5p:mirSVR_highEffct hsa-miR-515-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.24E-35 2.78E-31 2.03E-33 1.86E-32 91 1656 "SFTA3,COG6,SNX24,APAF1,MSH2,ARL1,ASCL1,NCOA1,ATP1A2,SLC4A4,ZNF542P,CD84,ARHGEF7,NFKBIA,PNP,CAST,PCCA,CDK7,PDGFRA,GLT1D1,PIWIL1,ZNF595,PGGT1B,TSTD1,ITGBL1,ADGRF3,AKAP6,TAPT1,POU2F1,LYSMD3,SNCAIP,C12orf65,LRRTM2,DNM3,UBXN2A,FCRL5,NOS1AP,IFT172,MATR3,OCIAD1,SACS,G3BP2,RABGAP1L,GNPDA2,NR1H4,RGS12,NTN4,RNF4,EIF2B1,ELF1,BORA,SAP18,ETF1,ABCA11P,ADGRV1,PCBD2,GORAB,FNIP1,MROH9,FBXO11,GFM2,ARHGEF40,TADA1,ZNF605,N4BP2,GABRB1,ATP8A2,HSPH1,KDM3B,DRC1,RBKS,ANKLE2,LRCH1,IKBIP,LPIN1,PPARGC1A,RNF212,RNF17,LINC01551,AP4S1,MAEL,ZNF721,NPL,ADAMTS19,RXFP2,ZNF140,KIF2A,DNAH10,AXDND1,LMNB1,SKA3" MicroRNA hsa-miR-1272:mirSVR_highEffct hsa-miR-1272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.01E-35 3.19E-31 2.31E-33 2.12E-32 89 1585 "RALGAPA1,KIAA1211,ANKRD34B,APAF1,APC,AACS,NCOA1,STARD13,NFATC4,ADGRD1,NOVA1,CD1E,PCCA,PCDH9,ZMYM5,FAM177A1,RGSL1,PDGFRA,WDFY2,AKAP6,RCHY1,LYSMD3,NGDN,VCAN,CEP135,GLT8D2,ZFYVE16,BIVM,COG3,OCIAD1,SACS,DNMT3A,RB1,AASDH,DTD2,RGS4,EFNA5,TXNDC15,MARVELD2,FAM172A,SAP18,ETF1,PCGF3,SLC22A17,FCGR3A,GORAB,FNIP1,TNFRSF19,POLK,PAICS,GFM2,IVNS1ABP,TADA1,CCDC88A,NR5A2,PDS5B,NAAA,EAPP,NPAS3,MCCC2,IKBIP,PCDH17,ZBTB37,ATP11A,ADGRA3,ANO4,ACSL6,TCF7,EML4,KMT5A,COP1,CRB1,LINC01551,BAZ1A,TENT2,VRK2,HTR2A,STARD4,NSD2,ZNF26,KCNT2,ZBTB41,PGAM5,DIAPH3,LETM1,RMST,SPRYD7,AXDND1,LOX" MicroRNA hsa-miR-1259:mirSVR_lowEffct hsa-miR-1259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.33E-35 3.37E-31 2.41E-33 2.21E-32 98 1928 "MCC,IL17D,ADD1,ULK1,FAM193A,CD84,RAB29,NOVA1,RILPL1,SCARB1,PDE4D,PDGFRA,CHD1,PFKFB2,MRPL57,BOD1L1,HECTD1,COPA,CRHBP,FAM169A,EIF2AK2,NOS1AP,DDX59,ZFYVE16,COG3,LOC439933,DHX9,NUDT12,TBC1D4,OCIAD1,GNPDA2,PARPBP,RASA1,RB1,ARGLU1,TMEM161B,SMC6,LATS2,MBNL2,ELK3,KLHL12,DHRS2,TBC1D19,ARSK,CWC27,DLEU1,DNAJC27,ADGRV1,PCGF3,SULT6B1,FGF9,FOXO1,FMO1,VEZT,RUBCNL,G2E3,BRMS1L,MBIP,SLC8A1,THADA,CCDC88A,SLC22A4,UGGT2,SNRPF,MEGF10,MYT1L,ERAP1,CMPK2,GC,NEDD1,LRCH1,KLHL20,PCDH17,GJA3,SCFD1,SPIC,GRSF1,CRB1,MAEL,NPL,UBE2K,SLAIN1,TENT2,NLRP8,FCRL6,IGF1,ZNF470,SELENOI,CCDC169,ZBTB41,FAM151B,LMLN,KCNN2,KIF2A,KIT,TTC41P,RMST,LIG4" MicroRNA hsa-miR-890:mirSVR_lowEffct hsa-miR-890:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.34E-35 3.37E-31 2.41E-33 2.21E-32 90 1623 "ANKRD34B,SEMA6A,CUL4A,APC,CDKL4,ARHGAP5,FAM193A,ATP2B4,STARD13,KCTD12,BCL2L2,CACNA1E,FCHO2,CD1D,SCARB1,PAH,TSSK4,ZMYM5,RGSL1,PDGFRA,PIGR,SNX6,AKAP6,STRN3,RCHY1,GNPTAB,VCAN,LRRTM2,CEP135,SPATA18,EPS8L1,RABGAP1L,WDR1,PARPBP,DNMT3A,RASA1,OGFOD2,DTD2,EIF2D,PACRGL,RNASEL,GRTP1,DHRS2,ZNF671,DNAJC27,ADGRV1,FCGR3A,SPON2,N4BP2L2,TNFRSF19,SUCO,SDC1,FTLP10,CCDC92,PAICS,CYP1B1-AS1,PDS5B,NAAA,ZNF274,UHRF1BP1L,IKBIP,MIMT1,MAST4,ZNF544,GOLGA3,LILRB4,GPR12,STON1,RNF212,GRSF1,TFDP1,CRB1,TGFBI,GTF3C2,ACTR6,TMPO,HGFAC,HSD17B4,ZNF876P,TENT2,WDR36,NSD2,IGF1,ZNF470,SELENOI,ZBTB41,FIP1L1,LINC01913,LETM1,SPRYD7" MicroRNA hsa-miR-633:mirSVR_highEffct hsa-miR-633:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.47E-35 3.44E-31 2.44E-33 2.24E-32 88 1550 "MAP1B,MATN3,SMIM15,BIRC6,TMEM132B,KIAA1211,NLN,COG6,DDX55,NOVA1,GAS2L3,TAF1B,ZNF664,PIWIL1,CHD1,PGGT1B,LINC01085,BOD1L1,THAP6,HOMER1,AKAP6,STRN3,GNPTAB,PREPL,LACC1,LRRTM2,FCRL5,EIF2AK2,GLT8D2,SPATA18,SREK1,COG3,DMXL1,CEP350,NUDT12,COCH,PARPBP,ZNF329,SMC6,DTD2,CLIP4,POLR1D,NTN4,SETDB2,LATS2,MBNL2,SPATA9,MPHOSPH9,ELOVL7,TRAPPC13,UTP15,FLT1,FBXO11,PLEKHA6,IVNS1ABP,CCDC88A,SLC22A5,MRPS14,FSHR,LIMCH1,SNRPF,MYT1L,RAPGEF6,UHRF1BP1L,HSPH1,RBKS,NEDD1,PPARGC1A,GJA3,TMED2,METAP2,ACSL6,STON1,RNF212,ZBTB49,RAB2B,HSP90B1,TECRL,ZNF550,HSD17B4,TPTE2,JCHAIN,SPTSSA,LHX9,RMST,LIG4,CDK2AP1,IFT88" MicroRNA hsa-miR-302a*:mirSVR_highEffct hsa-miR-302a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.55E-35 3.49E-31 2.45E-33 2.25E-32 86 1478 "SMIM15,ACOX3,ANKRD34B,SEMA6A,ULK1,SNX24,BLZF1,ARL1,CCDC181,ATP2B4,NOVA1,CBLN3,CDKL2,MPZL1,MORN2,CHAMP1,ZMYM5,SCFD2,CHD1,CCDC122,ATAD2B,ADGRF3,HECTD1,AKAP6,LYSMD3,DDX59,MATR3,SREK1,PTGS2,DMXL1,DHX9,CEP350,PTPRC,SACS,G3BP2,GNPDA2,PARPBP,TSEN15,RNF219,B3GLCT,SMC6,DTD2,POLR1D,NTN4,TXNDC15,GRTP1,KLHL12,MARVELD2,DHRS2,ABCA11P,PCGF3,UTP15,GORAB,N4BP2L2,SUCO,FLT1,FBXO11,NBEA,CCDC92,PAICS,UGGT2,LIMCH1,MEGF10,MYT1L,PDS5B,NAAA,HSPH1,NFASC,NEDD1,ZBTB37,PPARGC1A,TBC1D1,SCFD1,ANO4,GPR12,KMT5C,TDG,RNF17,ZNF721,GUF1,POC5,YTHDC2,ZNF10,LMLN,FIP1L1,LOX" MicroRNA hsa-let-7f-2*:mirSVR_highEffct hsa-let-7f-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.84E-35 3.64E-31 2.54E-33 2.33E-32 93 1737 "RALGAPA1,BLZF1,ATP1A2,MYBPC1,STARD13,KCTD12,FCRL3,BTF3,CBLN3,CDKL2,CHAMP1,PAH,SCFD2,CFL2,GPR180,HECTD1,AKAP6,STRN3,TAPT1,LYSMD3,SNCAIP,CSNK1G3,VCAN,GLT8D2,BIVM,PTGS2,LOC439933,NUDT12,CEP120,SUPT7L,PARPBP,EGLN3,RASA1,RB1,TMEM161B,AASDH,IPO4,MEMO1,MBNL2,DCUN1D2,GP6,DRAM1,ABCA11P,FNIP1,FGFR3,SUCO,FOXO1,HSD17B7,SUPT20H,SFSWAP,ZCCHC8,SGCG,BRMS1L,SLC8A1,PKD2L2,N4BP2,CPSF3,MYO16,PDS5B,EAPP,IQGAP2,ERAP1,OXGR1,ANKLE2,ERBIN,PCDH17,PPARGC1A,INSM2,ADAM17,PPIP5K2,ADGRA3,GPR18,ARHGEF28,EML4,YIPF7,MSH6,LINC01551,AP4S1,BAZ1A,ZNF721,NPL,HEXB,HSP90B1,GPN1,HMGCR,TECRL,TMEM174,ZNF10,CCDC169,ZNF140,KIT,RMST,LMNB1" MicroRNA hsa-miR-146a*:mirSVR_highEffct hsa-miR-146a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.96E-35 3.70E-31 2.57E-33 2.35E-32 90 1625 "HOMEZ,RGS5,APAF1,DDX55,STXBP6,LINC02347,NOVA1,DAOA,CACNA1E,TAF1B,CDK17,CFL2,WDFY2,JAKMIP1,UGT2B28,PMCH,RCHY1,HEATR5A,UBXN2A,FCRL5,ZNF586,SREK1,FBXL5,LOC439933,NUDT12,TBC1D4,CEP120,F11R,PARPBP,DNMT3A,RB1,ARGLU1,LAP3,CLIP4,POLR1D,CRYL1,GUSBP3,PACRGL,RNF4,MARVELD2,TBC1D19,ABCA11P,FCGR3A,N4BP2L2,RELL1,POLK,SUCO,FLT1,HSD17B7,SGCG,TM9SF1,RUBCNL,ALKAL2,GFM2,PKD2L2,N4BP2,SLC22A5,YPEL5,UGGT2,GABRA2,PDS5B,ATP8A2,NPAS3,PCDH17,NPFFR2,SCFD1,PPIP5K2,ANO4,ACSL6,C5orf56,GPR12,CRB1,LINC01551,GTF2H3,RAB2B,TMPO,RIMBP2,HEXB,GUF1,UGT2B7,ZNF26,IL6ST,SPTSSA,NPHS2,CAB39L,RMST,SPRYD7,AXDND1,IFT88,LOX" MicroRNA hsa-miR-367:mirSVR_lowEffct hsa-miR-367:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.46E-35 3.97E-31 2.74E-33 2.51E-32 94 1777 "SFTA3,CUL4A,APAF1,APBB2,DDX55,BLZF1,ARHGAP5,ARL1,AACS,NCOA1,ASTN1,SLC4A4,ATP7B,NRL,CAMK4,SLC5A8,PCDH9,FAM177A1,CDK7,PDE4D,PDGFRA,SLC25A3,SMIM14,HOMER1,EPGN,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SREK1,PTGS2,LOC439933,CEP350,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DNMT3A,CLIP4,POLR1D,SPATA9,LGR6,TBC1D19,GP6,FAM172A,DEPDC4,STK32B,DNAJC27,PCGF3,ELOVL7,GORAB,FOXG1,HSD17B7,RASA3,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,CMPK2,MCCC2,ERBIN,IKBIP,PCDH17,STRN,ADAM17,PPIP5K2,METAP2,EML4,KMT5C,RNF17,LINC01551,ADAMTS19,TRPC4,HMGCR,TMEM174,VRK2,WDR36,YTHDC2,ZNF470,IRF1,ZBTB41,TMEM178A,DIAPH3,KIR2DS4,LAD1" MicroRNA hsa-miR-1208:mirSVR_lowEffct hsa-miR-1208:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.85E-35 4.71E-31 3.22E-33 2.95E-32 98 1936 "MAP1B,MDM4,TMEM132B,ADD1,KIAA1211,ADCY4,PPFIA4,NCOA1,ATP2B4,BCL2L2,NOVA1,TAF1B,CD1E,SCARB1,DCLK1,PCK2,FAM177A1,CDK17,PDGFRA,CENPC,PFKFB2,SLC25A3,GPR180,SMIM14,ATAD2B,LTB4R,POLN,ANAPC4,MPC2,RCHY1,GNPTAB,EPGN,DNM3,DDX59,ZNF586,TBC1D4,RABGAP1L,WDR1,C14orf119,TSEN15,RNF219,RGS12,ZNF419,NTN4,PACRGL,ELK3,MPHOSPH9,FCAMR,STX2,FNIP1,N4BP2L2,FOXO1,SUPT20H,FBXO11,DDX51,BRMS1L,PLEKHA6,UFM1,GFM2,SLC30A6,SCYL2,ZNF605,SLC12A2,UGGT2,MEGF10,KDM5B,JPH4,GJB6,NFASC,IKBIP,PCDH17,LPIN1,GJA3,MAST4,PPIP5K2,GOLGA3,CNTN2,C5orf56,DOCK9,NT5C1B,GRSF1,GTF2H3,GTF3C2,TPO,ADAMTS19,TENT2,VRK2,STARD4,NSD2,FCRL6,TADA2B,ZMYM2,TDRD3,FIP1L1,KIF2A,KIR2DL4,KIR2DS4,LAD1" MicroRNA hsa-miR-138-1*:mirSVR_lowEffct hsa-miR-138-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.64E-35 5.13E-31 3.49E-33 3.19E-32 90 1632 "SMIM15,HOMEZ,RGS5,APBB2,BLZF1,ARL1,NCOA1,ASTN1,PPP1R12B,ARHGEF7,CHAMP1,SCARB1,PCDH9,PFKFB2,CCDC122,SLC25A3,SNX6,PIK3C2B,ATAD2B,TAPT1,RCHY1,LRRTM2,CEP135,FAM169A,ZFYVE16,SREK1,NUDT12,OCIAD1,SACS,GNPDA2,SLC35F6,PARPBP,FAM129A,ARGLU1,RGS4,RGS12,LRPPRC,MBNL2,FAM172A,DRAM1,FAM81B,CWC27,ABCA11P,ADGRV1,TOMM40L,FGF9,TNFRSF19,SDC1,TADA1,ZNF605,SLC12A2,PKD2L2,NR5A2,DCAF11,CYP1B1-AS1,NMNAT2,GJB6,HSPH1,KDM3B,PCDH17,COMMD6,STRN,ATP11A,PPIP5K2,METAP2,ADGRL3,GPR12,STON1,RASSF6,FZD10,ZNF721,TNR,ATP6V0A2,TECRL,SLAIN1,NSD2,JCHAIN,ZNF470,IL6ST,PLB1,ANKS1B,LINC00272,TDRD3,ZBED3-AS1,DNAH10,NUAK2,AXDND1,ZDHHC20,LMNB1,SKA3" MicroRNA hsa-miR-216b:mirSVR_lowEffct hsa-miR-216b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-34 5.54E-31 3.74E-33 3.43E-32 95 1823 "RALGAPA1,MCC,ADD1,ATP6V1G3,ANKRD34B,WDR35,SNX24,UVSSA,NCOA1,STARD13,LINC02347,RAB29,CDKL2,MPZL1,PCDH9,PCK2,SCFD2,CENPC,GPR180,CFAP45,C1orf116,LYSMD3,CLOCK,NOS1AP,DCAF8,ZFYVE16,EPS8L1,CEP350,COCH,GNPDA2,LINC01257,FAM129A,AASDH,LAP3,RGS12,CLIP4,GRTP1,EIF2B1,ELF1,MPHOSPH9,TBC1D19,PCOTH,ARSK,CWC27,ABCA11P,PCGF3,F10,FCAR,FGF9,RELL1,FLT1,FTLP10,PLEKHA6,IVNS1ABP,THADA,ZNF605,SLC12A2,PKD2L2,N4BP2,MEGF10,PDS5B,ZNF274,DRC1,MCCC2,ERBIN,IKBIP,TBC1D1,TMED2,ADGRL3,GPR12,ARHGEF28,EML4,KHNYN,RNF17,CRB1,ATP6V0A2,ADAMTS19,TECRL,TXK,POC5,HTR2A,ZNF10,ZNF84,PLB1,ZNF140,GALP,ANKS1B,ZMYM2,KCNN2,KIT,TTC41P,LCP1,TTC7A,AXDND1,LMNB1" MicroRNA hsa-miR-34c-3p:mirSVR_highEffct hsa-miR-34c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-34 6.45E-31 4.33E-33 3.96E-32 66 836 "SMIM15,APC,WDR19,ATP7B,CDKL2,CAMK4,TAF1B,FCHO2,ZNF664,CDK7,SCFD2,CDK17,PDE4D,PDGFRA,CFL2,VIT,PGGT1B,PIK3C2B,HOMER1,AKAP6,STRN3,HEATR5A,LYSMD3,SNCAIP,LRRTM2,DCT,DHX9,NUDT12,RNF219,SMC6,RNASEL,MBNL2,UGT2A3,CWC27,ADGRV1,SUCO,PEAR1,FLT1,FLT3,SUPT20H,VEZT,G2E3,IVNS1ABP,SLC8A1,TADA1,CCDC88A,NR5A2,GABRA2,MYT1L,PCDH17,BRD8,PSME4,PPIP5K2,ADGRL3,ACSL6,NPL,YTHDC2,FCRL6,CHPT1,CAB39L,KIF2A,TTC41P,RMST,IFT88,PABPN1,MICU2" MicroRNA hsa-miR-421:mirSVR_highEffct hsa-miR-421:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.29E-34 6.87E-31 4.58E-33 4.19E-32 83 1385 "ADD1,WDR35,FBRSL1,DDX55,ARL1,SLC4A4,ZNF542P,MYBPC1,ATP7B,RILPL1,LDB2,PAH,FCRLB,SNTG2,ZNF664,RGSL1,CFL2,SLC25A3,GPR180,ATAD2B,THAP6,HOMER1,AKAP6,STRN3,PREPL,PRKD1,FCRL2,ZFYVE16,PSME1,TBC1D4,SACS,RABGAP1L,NR1H4,RASA1,TMEM161B,ZNF329,IPO4,DTD2,SLC9C2,NTN4,SETDB2,PACRGL,RNASEL,ELK3,STX2,FAM172A,DNAJC27,ABCA11P,GORAB,N4BP2L2,RELL1,SUCO,VEZT,SLC12A2,TMEM132D,C1orf112,SF3B6,YPEL5,LIMCH1,MYT1L,ERAP1,LRCH1,ERBIN,PCDH17,NMU,COMMD6,LPIN1,GJB2,ADGRL3,COP1,NT5C1B,AP4S1,RAB2B,TMPO,ZNF721,ADAMTS19,NSD2,ZNF26,IL6ST,FAM151B,EP400P1,TTC41P,MICU2" MicroRNA hsa-miR-155*:mirSVR_highEffct hsa-miR-155*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-34 7.22E-31 4.78E-33 4.38E-32 79 1248 "KIAA1211,EP400,PPFIA4,MSH2,ARL1,ZNF542P,STARD13,ATP7B,CACNA1E,FCHO2,MORN2,CD1D,SCARB1,CENPC,CFL2,VIT,SLC25A3,THAP6,AKAP6,TAPT1,LYSMD3,PREPL,C12orf65,SREK1,DMXL1,CEP350,CEP120,DHFR,SUPT7L,SLC35F6,TSEN15,RNF219,B3GLCT,FAM228A,RGS12,ZNF419,POLR1D,TXNDC15,RNF4,FAM172A,ELOVL7,TNFRSF19,RELL1,FOXG1,SUPT20H,NBEA,CCDC88A,SLC15A4,SLC22A4,YPEL5,PUS1,MEGF10,PDS5B,GJB6,MRPS27,MCCC2,MIMT1,SULT1E1,PSME4,ADGRL3,COX18,RNF17,TEP1,CRB1,BAZ1A,RASSF6,MAEL,ADAMTS19,TXK,ZNF550,HTR2A,WDR36,DCP2,ZNF140,DIAPH3,AMTN,LINC01913,LCP1,LIG4" MicroRNA hsa-miR-130b:mirSVR_lowEffct hsa-miR-130b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-34 7.41E-31 4.88E-33 4.47E-32 93 1753 "MAP1B,MCC,ADD1,NLN,PITPNM2,RGS5,APBB2,APC,ZNF784,ARHGAP5,ASCL1,CENPBD1P1,ATP1A2,SLC4A4,MYH6,NFATC4,AP1G2,NOVA1,UHMK1,DCLK1,PDE4D,CEBPE,CHD1,HECTD1,STRN3,TAPT1,HEATR5A,ITSN2,LRRTM2,FAM169A,KIAA0040,MATR3,SNX17,COG3,KLHL3,NUDT12,G3BP2,WDR1,PPP2R3C,RNF219,EGLN3,FAM129A,ATG10,OGFOD2,CLIP4,LRPPRC,RNASEL,EFNA5,GRTP1,ELF1,DHRS2,ZNF671,PCGF3,FOXG1,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,TMEM183A,IQGAP2,GJB6,RBKS,NEDD1,COMMD6,PPARGC1A,TBC1D1,ATP11A,MTUS2,ADGRA3,RIPK3,DOCK9,TGM1,LINC01551,RIMBP2,ATP6V0A2,HSP90B1,UBE2K,RXFP2,ZNF876P,NSD2,ZNF10,IGF1,ZMYM2,ZBTB41,LHX9,FAM151B,ZAR1L,KCNN2,KIT,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-590-5p:mirSVR_lowEffct hsa-miR-590-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-34 8.05E-31 5.25E-33 4.81E-32 86 1495 "SMIM15,NLN,NOP14,ASCL1,ATP2B4,KCTD12,LINC02347,NOVA1,PNP,CACNA1E,UHMK1,PDE4D,PIWIL1,PFKFB2,WDFY2,CFAP54,SMIM14,ATAD2B,HOMER1,TAPT1,CSNK1G3,ITSN2,LRRTM2,CEP135,DNM3,NOS1AP,ZFYVE16,MATR3,COCH,CEP120,PTPRC,OCIAD1,GNPDA2,SLC35F6,TMEM161B,MBNL2,SPATA9,DLEU1,FGF9,SUCO,FOXG1,VEZT,ZCCHC8,SGCG,SLC34A2,NBEA,DDX51,BRMS1L,PLEKHA6,ALKAL2,MBIP,C1orf112,YPEL5,DCAF11,CYP1B1-AS1,RAPGEF6,UHRF1BP1L,HSPH1,NEDD1,IKBIP,LPIN1,CNTN2,ADGRA3,ANO4,STON1,KMT5C,XPO4,TDG,COX18,NCSTN,GRSF1,CRB1,AP4S1,ACTR6,HMGCR,GUF1,PAPPA2,VRK2,JCHAIN,PLB1,ZBTB41,LHX9,LETM1,NUAK2,LMNB1,PABPN1" MicroRNA hsa-miR-3161:mirSVR_lowEffct hsa-miR-3161:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-34 8.10E-31 5.25E-33 4.81E-32 93 1755 "SEMA6A,UVSSA,APC,LINC02347,CAST,CHAMP1,CCNB1,PAH,NFXL1,ZNF664,DCLK1,FAM177A1,PCSK1,CDK18,CHD1,PGGT1B,ITGBL1,TM9SF2,LINC01085,BOD1L1,STRN3,MPC2,TAPT1,RCHY1,CLOCK,NCOR2,SNCAIP,FAM169A,UBXN2A,DDX59,DCAF8,MATR3,SPATA18,CEP350,PTPRC,OCIAD1,GNPDA2,MTX3,DHFR,PARPBP,DNMT3A,FAM129A,TMEM161B,SETDB2,RNF4,MBNL2,UGT2A3,DHRS2,BORA,ABCA11P,PCBD2,TOMM40L,GORAB,FGF9,POLK,FLT1,FLT3,HSD17B7,STAB2,NUBPL,MBIP,SLC30A6,C1orf112,NR5A2,UGGT2,LIMCH1,MYT1L,FAM114A1,IQGAP2,HSPH1,OXGR1,NPAS3,CMPK2,SRP54,ERBIN,NPFFR2,UGT2A1,PPIP5K2,GOLGA3,SPIC,HEXB,TECRL,ZNF876P,NSD2,YTHDC2,IL6ST,CCDC169,LHX9,ZBED3-AS1,AMTN,MFSD2B,LINC01913,SPRYD7" MicroRNA hsa-miR-222*:mirSVR_lowEffct hsa-miR-222*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-34 8.14E-31 5.25E-33 4.81E-32 90 1642 "SLAMF6,SNX24,APC,PPP1R12B,ARHGEF7,RAB29,CACNA1E,FCHO2,CD1D,SCARB1,UHMK1,RGSL1,CHD1,SNX6,BOD1L1,LYSMD3,CEP135,FCRL5,ZFYVE16,MATR3,SREK1,FBXL5,CEP350,KLHL3,NUDT12,CEP120,PPP2R3C,RNF219,DNMT3A,FAM129A,B3GLCT,TMEM161B,NTN4,LATS2,SPATA9,DRAM1,PCBD2,TOMM40L,N4BP2L2,RELL1,POLK,PEAR1,MROH9,FLT1,CCDC92,UFM1,STPG4,TADA1,N4BP2,MYO16,PDS5B,ATP8A2,NPAS3,MCCC2,NEDD1,LRCH1,IKBIP,MIMT1,NMU,PPARGC1A,GJA3,UGT2A1,UTP20,COX7B2,METAP2,ADGRA3,ANO4,EML4,KMT5A,RNF212,COX18,TFDP1,CRB1,GPR161,AP4S1,TMPO,RIMBP2,ADAMTS19,HSD17B4,WDR36,IGF1,ZNF84,IL6ST,ZMYM2,LHX9,TDRD3,FIP1L1,EP400P1,LINC01913,LTA4H" MicroRNA hsa-miR-888:mirSVR_highEffct hsa-miR-888:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-34 8.19E-31 5.25E-33 4.81E-32 89 1605 "MAP1B,MCC,COG6,SNX24,DDX55,BLZF1,ARL1,SLC4A4,KCTD12,CAMK4,MPZL1,UHMK1,CDK17,CDK18,PDE4D,RCBTB2,PFKFB2,CCDC122,GPR180,LINC01085,SMIM14,THAP6,HOMER1,FAM53A,LYSMD3,PREPL,CEP135,BIVM,COG3,DMXL1,FBXL5,NUDT12,G3BP2,DHFR,RNF219,FAM129A,SLC9C2,RGS4,LATS2,MBNL2,TRAPPC12,ETF1,ADGRV1,TLR6,PCGF3,UTP15,GORAB,FNIP1,N4BP2L2,PIBF1,FOXG1,SUPT20H,SFSWAP,VEZT,ALKAL2,IVNS1ABP,SLC22A4,NR5A2,ZNF667,NMNAT2,ERAP1,HSPH1,ERBIN,IKBIP,PPARGC1A,GJB2,TBC1D1,TMED2,ADGRL3,GPR12,KMT5A,NT5C1B,MSH6,BAZ1A,TMPO,WDR36,ZNF10,ZNF26,KCNT2,CENPH,CCDC169,SPTSSA,ZMYM2,NPHS2,ZBED3-AS1,CHPT1,IFT88,PABPN1,LOX" MicroRNA hsa-miR-10a*:mirSVR_lowEffct hsa-miR-10a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-34 8.46E-31 5.39E-33 4.94E-32 93 1756 "BIRC6,NLN,SLAMF6,COG6,ULK1,APAF1,MSH2,BLZF1,STXBP6,ASCL1,NCOA1,CCDC181,BTF3,CCNA1,NOVA1,DAOA,NRL,CAST,LDB2,CD1D,FCRLB,PCSK1,PDGFRA,CKMT2,ITGBL1,SNX6,NUP37,ATAD2B,AKAP6,TAPT1,RCHY1,HEATR5A,VCAN,DDX59,BIVM,SREK1,COG3,LOC439933,CEP350,TBC1D4,PTPRC,OCIAD1,PARPBP,DNMT3A,EGLN3,AASDH,CLIP4,ELF1,ELK3,ADGRV1,FGF9,SUCO,RUBCNL,FBXO11,MBIP,CCDC88A,C1orf112,NR5A2,UGGT2,MYT1L,IQGAP2,GJB6,KDM3B,NEDD1,COMMD6,STRN,UGT2A1,PPIP5K2,ANO4,STON1,KMT5A,DOCK9,YIPF7,TFDP1,ZBTB49,BAZ1A,ADAMTS19,HSP90B1,GPN1,SLAIN1,WDR36,JCHAIN,ANKS1B,ZMYM2,ZBTB41,FAM151B,ZBED3-AS1,FIP1L1,DIAPH3,TTC41P,DNAH10,LMNB1,IFT88" MicroRNA hsa-miR-891b:mirSVR_lowEffct hsa-miR-891b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-34 8.76E-31 5.55E-33 5.08E-32 87 1533 "MAP1B,MCC,MDM4,TMEM132B,ADD1,ANKRD34B,COG6,SEMA6A,ARHGAP5,ARL1,NOVA1,MPZL1,FCHO2,MORN2,NFXL1,SLC5A8,FAM177A1,PGGT1B,ITGBL1,NUP37,ATAD2B,BOD1L1,STRN3,RCHY1,TOGARAM2,LYSMD3,CRHBP,SNCAIP,CEP135,UBXN2A,PRKD1,FCRL5,SPATA18,SREK1,KLHL3,SLC35F6,NR1I3,RASA1,ZNF329,SLC9C2,MEMO1,SETDB2,EIF2D,LATS2,MBNL2,ELF1,ADGRV1,PCGF3,TRAPPC13,PCBD2,FCGR3A,N4BP2L2,RELL1,PEAR1,FBXO11,BRMS1L,THADA,SLC12A2,PKD2L2,C1orf112,GABRA2,PDS5B,DRC1,MCCC2,ERBIN,LPIN1,PPARGC1A,GOLGA3,GRSF1,GTF3C2,ACTR6,RIMBP2,NPL,HEXB,UBE2K,GPN1,HSD17B4,TENT2,YTHDC2,ZBED3-AS1,CHPT1,NUAK2,AXDND1,ZDHHC20,IFT88,PABPN1,LTA4H" MicroRNA hsa-miR-454:mirSVR_highEffct hsa-miR-454:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.68E-34 8.94E-31 5.62E-33 5.15E-32 88 1570 "RALGAPA1,MATN3,MDM4,BIRC6,KIAA1211,WDR35,ULK1,APAF1,APC,BLZF1,ARL1,NCOA1,ATP12A,ZNF542P,STARD13,CD84,BTF3,DAOA,CBLN3,CDKL2,CAST,FCGR2C,SNTG2,PCDH9,CDK17,PDGFRA,CFL2,PFKFB2,GPR180,JAKMIP1,HOMER1,AKAP6,FAM53A,GNPTAB,HEATR5A,LYSMD3,CLOCK,DNM3,DCAF8,ZFYVE16,FBXL5,NUDT12,CEP120,PARPBP,RASA1,AASDH,MEMO1,ELK3,MPHOSPH9,SAP18,CLIP1,F10,GORAB,N4BP2L2,PIBF1,PEAR1,VEZT,NBEA,SLC8A1,CCDC88A,C1orf112,ZNF667,MEGF10,MYT1L,KDM5B,ERAP1,CMPK2,LRCH1,ERBIN,KLHL20,NPFFR2,INSM2,RNF17,ADAMTS19,TXK,UBC,SLAIN1,TENT2,ZMYM2,IRF1,LMLN,CAB39L,DIAPH3,RNASE11,TTC41P,RMST,LIG4,LMNB1" MicroRNA hsa-miR-27b:mirSVR_highEffct hsa-miR-27b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.90E-34 1.01E-30 6.32E-33 5.79E-32 87 1536 "RALGAPA1,MATN3,ADORA1,KIAA1211,NLN,WDR35,SEMA6A,MSH2,NCOA1,ATP1A2,ZNF542P,B4GALT3,CCNA1,NOVA1,CD1E,SCARB1,PCDH9,PCK2,RGSL1,PDGFRA,PDE6B,CFL2,VIT,WDFY2,SLC25A3,NRXN1,PIGR,LINC01085,SMIM14,UGT2B28,TAPT1,PM20D1,HEATR5A,LYSMD3,VCAN,ITSN2,CEP135,PRKD1,FCRL5,FCRL2,DCAF8,PIGG,SREK1,COG3,TBC1D4,ATG10,RASA1,RNASEL,EFNA5,MBNL2,ELK3,DLEU1,F10,TRAPPC13,TOMM40L,SUCO,FOXO1,STAB2,SFSWAP,RUBCNL,SLC8A1,WDCP,C1orf112,NR5A2,PDS5B,IQGAP2,ERAP1,ERBIN,LPIN1,PPARGC1A,ZNF544,MTUS2,ADGRA3,RNF17,CRB1,ACTR6,MAEL,NPL,HEXB,STARD4,CCDC169,ZNF140,TMEM178A,CAB39L,AMTN,LINC00442,LOX" MicroRNA hsa-miR-633:mirSVR_lowEffct hsa-miR-633:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.99E-34 1.06E-30 6.56E-33 6.00E-32 95 1838 "MCC,MCFD2,ARL1,FAM193A,ASTN1,CCDC181,ATP2B4,KCTD12,MPZL1,RILPL1,ODC1,SLC5A8,PCDH9,DCLK1,ZMYM5,CENPC,CCDC122,ITGBL1,CFAP54,TAPT1,HEATR5A,CLOCK,VCAN,FAM169A,DNM3,NOS1AP,BIVM,PTGS2,OCIAD1,G3BP2,MTX3,RB1,TMEM161B,RGS12,GUSBP3,PACRGL,RNASEL,EFNA5,RNF4,ELF1,KLHL12,LGR6,MARVELD2,TBC1D19,SAP18,ETF1,ADGRV1,USP44,FNIP1,N4BP2L2,FGF9,NUBPL,UFM1,ARHGEF40,N4BP2,NR5A2,EFR3B,PUS1,ACIN1,MYO16,MEGF10,GABRB1,PDS5B,KDM3B,NFASC,LRCH1,ERBIN,KLHL20,UGT2A1,PPIP5K2,MTUS2,GOLGA3,ADGRL3,COX18,TFDP1,GTF2H3,ACTR6,RIMBP2,HAL,SLAIN1,PAPPA2,HTR2A,KCNT2,ZNF470,ZNF84,GALP,ANKS1B,ZMYM2,FAM151B,TDRD3,CHPT1,FIP1L1,DIAPH3,TTC41P,AXDND1" MicroRNA hsa-miR-27a:mirSVR_highEffct hsa-miR-27a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.03E-34 1.08E-30 6.66E-33 6.10E-32 86 1501 "RALGAPA1,MATN3,ADORA1,KIAA1211,NLN,WDR35,SEMA6A,MSH2,NCOA1,ATP1A2,B4GALT3,CCNA1,NOVA1,CD1E,SCARB1,PCDH9,PCK2,RGSL1,PDGFRA,PDE6B,CFL2,VIT,WDFY2,NRXN1,PIGR,LINC01085,SMIM14,UGT2B28,HOMER1,TAPT1,PM20D1,HEATR5A,LYSMD3,VCAN,ITSN2,CEP135,PRKD1,FCRL5,FCRL2,DCAF8,PIGG,SREK1,COG3,TBC1D4,ATG10,RNASEL,EFNA5,MBNL2,ELK3,FAM172A,DLEU1,F10,TRAPPC13,TOMM40L,SUCO,FOXO1,STAB2,SFSWAP,RUBCNL,SLC8A1,WDCP,C1orf112,NR5A2,PDS5B,IQGAP2,ERAP1,ERBIN,PCDH17,LPIN1,PPARGC1A,ZNF544,MTUS2,ADGRA3,CRB1,ACTR6,MAEL,NPL,HEXB,STARD4,CCDC169,ZNF140,TMEM178A,CAB39L,AMTN,LINC00442,LOX" MicroRNA hsa-miR-1297:mirSVR_lowEffct hsa-miR-1297:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.55E-34 2.42E-30 1.48E-32 1.35E-31 93 1780 "MAP1B,NLN,PPFIA4,BLZF1,ARL1,NOVA1,ODC1,FCHO2,ZNF664,FAM177A1,XPR1,PDE4D,PDGFRA,CENPC,RCBTB2,CHD1,PFKFB2,SLC25A3,GPR180,MRPL57,SNX6,THAP6,HOMER1,AKAP6,SYCP3,PREPL,LACC1,IL20,ITSN2,DDX59,MATR3,NUDT12,OCIAD1,PTPRH,RABGAP1L,TMEM161B,AASDH,REST,TMEM33,RNASEL,MBNL2,EIF2B1,ETF1,PCGF3,TNFRSF19,POLK,FOXO1,SUPT20H,ALKAL2,NUBPL,TADA1,SLC12A2,N4BP2,YPEL5,UGGT2,KIF21B,CENPJ,IQGAP2,GJB6,OXGR1,CMPK2,LRCH1,KLHL20,PCDH17,GJA3,UGT2A1,SCFD1,ANO4,C5orf56,GPR12,ARHGEF28,KMT5A,KMT5C,RNF212,NPL,NSD2,YTHDC2,IGF1,KCNT2,ZMYM2,LHX9,TMEM178A,CAB39L,DIAPH3,KIR2DL1,KIR2DL4,KIR3DL1,KIR3DL2,AMTN,LETM1,AXDND1,LOX,MICU2" MicroRNA hsa-miR-519b-5p:mirSVR_lowEffct hsa-miR-519b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-519c-5p:mirSVR_lowEffct hsa-miR-519c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-519a*:mirSVR_lowEffct hsa-miR-519a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-522*:mirSVR_lowEffct hsa-miR-522*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-518e*:mirSVR_lowEffct hsa-miR-518e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-523*:mirSVR_lowEffct hsa-miR-523*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-34 2.50E-30 1.48E-32 1.35E-31 87 1555 "SMIM15,ADD1,NLN,CUL4A,FBRSL1,APC,RAD51AP2,ASCL1,SLC4A4,KCTD12,BCL2L2,AP1G2,NOVA1,DAOA,DCLK1,RGSL1,PDGFRA,SMIM14,NUP37,PKP1,HEATR5A,CLOCK,NGDN,DNM3,KIAA0040,SREK1,NUDT12,G3BP2,FAM129A,B3GLCT,TMEM161B,OGFOD2,RGS4,POLR1D,ELK3,MARVELD2,CLIP1,ELOVL7,POLK,SLC34A2,FBXO11,ALKAL2,TADA1,ZNF605,PKD2L2,C1orf112,LIMCH1,SNRPF,MYO16,MEGF10,PDS5B,CD244,IQGAP2,SRP72,RBKS,IKBIP,NPFFR2,PPARGC1A,BRD8,MAST4,UGT2A1,INSM2,ATP11A,PPIP5K2,ADGRL3,EML4,DOCK9,TEP1,GRSF1,CRB1,ZBTB49,RIMBP2,ADAMTS19,UBE2K,GPN1,SLAIN1,HTR2A,IGF1,JCHAIN,SPTSSA,ANKS1B,LHX9,FAM151B,CHPT1,DNAH10,AXDND1,LIG4" MicroRNA hsa-miR-625*:mirSVR_lowEffct hsa-miR-625*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-34 2.91E-30 1.71E-32 1.57E-31 82 1378 "BIRC6,NLN,ARHGAP5,ARL1,ZNF542P,STARD13,CCNA1,AMDHD1,LDB2,PAH,DCLK1,RGSL1,PFKFB2,SLC25A3,ATAD2B,BOD1L1,STRN3,SNCAIP,TTC37,VCAN,LRRTM2,FAM169A,KIAA0040,UBXN2A,PRKD1,COG3,NUDT12,CEP120,OCIAD1,GNPDA2,PARPBP,DNMT3A,B3GLCT,MEMO1,NTN4,RNF4,SNORA53,FAM172A,PCGF3,FNIP1,N4BP2L2,FGFR3,POLK,FOXG1,SGCG,NUBPL,UFM1,SLC8A1,ARHGEF40,TADA1,YPEL5,GABRA2,RAPGEF6,NEDD1,ERBIN,SULT1E1,PPARGC1A,GJA3,STRN,ZNF544,UTP20,ADGRL3,ANO4,ACSL6,DOCK9,NT5C1B,TFDP1,ZBTB49,NPL,ADAMTS19,GUF1,SLAIN1,NSD2,KCNT2,SELENOI,ZBED3-AS1,FIP1L1,CAB39L,DIAPH3,LINC01913,FAM71C,LIG4" MicroRNA hsa-miR-501-5p:mirSVR_highEffct hsa-miR-501-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.92E-34 3.15E-30 1.84E-32 1.69E-31 83 1415 "SMIM15,ANKRD34B,COG6,CUL4A,SNX24,BLZF1,WDR19,NCOA1,ATP2B4,SLC5A6,PNP,DAOA,MPZL1,CAST,FCHO2,CD1D,UHMK1,DCLK1,CDK17,RGSL1,PDE4D,CFL2,ADGRF3,UGT2B28,AKAP6,TAPT1,POU2F1,PREPL,BRI3BP,LACC1,UBXN2A,FCRL5,EPS8L1,SACS,DHFR,NR1H4,SLC9C2,LAP3,MBNL2,CWC27,FCGR3B,GORAB,N4BP2L2,TNFRSF19,PIBF1,POLK,FLT1,VEZT,G2E3,IVNS1ABP,ARHGEF40,PKD2L2,C1orf112,SNRPF,GABRB1,PDS5B,HSPH1,CMPK2,DRC1,NEDD1,PCDH17,MAST4,UGT2A1,METAP2,C5orf56,STON1,LINC01551,BAZ1A,MAEL,NPL,TECRL,GUF1,HTR2A,STARD4,KCNT2,CCDC169,PLB1,ZMYM2,TMEM178A,KCNN2,KIF2A,KIT,AXDND1" MicroRNA hsa-miR-4267:mirSVR_lowEffct hsa-miR-4267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.24E-34 3.32E-30 1.93E-32 1.77E-31 95 1865 "MCC,MDM4,KIAA1211,TBC1D14,HOMEZ,ADCY4,MSH2,ZNF784,BLZF1,B4GALT3,CARMIL3,NFATC4,ARHGEF7,BTF3,PNP,DAOA,PFKFB2,SNX6,JAKMIP1,PTPRVP,HOMER1,C1orf116,FAM53A,EPGN,GALNT9,CMTM5,NOS1AP,SNX17,BIVM,DGKQ,EPS8L1,PIGG,FBXL5,KLHL3,PARPBP,PPP2R3C,RNF31,RB1,RGS4,LAP3,RGS12,ZNF419,POLR1D,EFNA5,LATS2,RNF4,TRAPPC12,KIRREL1,DHRS2,ARSK,STK32B,MAEA,DLEU1,DNAJC27,PCBD2,FCAR,TOMM40L,TNFRSF19,SUCO,SDC1,HSD17B7,VEZT,SH3BP2,LIMCH1,NMNAT2,JPH4,NAAA,ZNF274,ERAP1,ATP8A2,MRPS27,NFASC,LRCH1,SULT1E1,ZBTB37,ADAM17,PPIP5K2,NT5C1B,SLC7A8,ZBTB49,ZNF876P,CENPH,PLB1,ZBED3-AS1,KCNJ9,LETM1,RMST,NUAK2,SPRYD7,TTC7A,AXDND1,ZDHHC20,LMNB1,SKA3,SPATA13" MicroRNA hsa-miR-182:mirSVR_lowEffct hsa-miR-182:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.56E-34 3.49E-30 2.02E-32 1.85E-31 97 1945 "MAP1B,ADD1,KIAA1211,COG6,SEMA6A,MCFD2,ARHGAP5,SLC4A4,ATP2B4,BCL2L2,SLC5A6,NOVA1,CAST,LDB2,PCCA,PCDH9,XPR1,WDFY2,GPR180,CKMT2,NRXN1,ATAD2B,PKP1,HECTD1,GNPTAB,TOGARAM2,HEATR5A,LYSMD3,DNM3,GLT8D2,SPATA18,COG3,DHX9,GNPDA2,DNMT3A,GALNT14,EGLN3,FAM129A,DTD2,CLIP4,POLR1D,NTN4,LRPPRC,RNF4,DHRS2,DEPDC4,ETF1,DNAJC27,TRAPPC13,FCAR,NDUFAF7,FGF9,SUCO,SDC1,SUPT20H,TM9SF1,G2E3,THADA,CCDC88A,SLC12A2,WDCP,C1orf112,CYP1B1-AS1,GABRA2,GABRB1,CIDEB,ATP8A2,HSPH1,NFASC,DRC1,LPIN1,GJA3,GJB2,PSME4,PPIP5K2,METAP2,ANO4,ACSL6,C5orf56,ARHGEF28,KMT5A,XPO4,RNF17,TFDP1,CRB1,GPN1,UGT2B7,SLAIN1,WDR36,NSD2,ZNF470,SELENOI,ZMYM2,KCNN2,TTC41P,SLAMF9,LCP1" MicroRNA hsa-miR-3155:mirSVR_lowEffct hsa-miR-3155:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.46E-34 3.97E-30 2.28E-32 2.09E-31 98 1988 "ABL2,MAP1B,MDM4,ADD1,ADORA1,KIAA1211,SLAMF6,MCFD2,AACS,ATP1A2,CADM3,MYH7,ATP7B,BCL2L2,NFATC4,ARHGEF7,NOVA1,CBLN3,CD1E,SNTG2,PDGFRA,GLT1D1,PDE6B,CFL2,RCBTB2,PIK3C2B,NCR1,THAP6,RNASE9,NGDN,CMTM5,NOS1AP,IFT172,TBC1D4,PTPRH,WDR1,C14orf119,TSEN15,NR1H4,B3GLCT,RNF31,RB1,SMC6,OGFOD2,FAM228A,IPO4,KIRREL1,DHRS2,NDUFAF7,FNIP1,LRRN2,TM9SF1,FBXO11,NUBPL,ARHGEF40,DCAF11,MEGF10,MYT1L,PDS5B,CENPJ,HSPH1,NFASC,LRCH1,IKBIP,MIMT1,ZBTB37,GJA3,MAST4,PSME4,ZNF544,ANO4,TCF7,RIPK3,KHNYN,XPO4,TDG,NCSTN,ACTR6,ZNF721,TNR,TRPC4,ZNF550,HSD17B4,ZNF876P,VRK2,NSD2,CENPH,ZFHX2,IRF1,FAM49A,KIF3C,KIR2DL4,KIR2DS4,EP400P1,C2orf70,LETM1,RMST,NUAK2" MicroRNA hsa-miR-455-5p:mirSVR_lowEffct hsa-miR-455-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.39E-34 4.46E-30 2.55E-32 2.34E-31 83 1422 "RALGAPA1,MAP1B,MDM4,BIRC6,ACOX3,KIAA1211,WDR35,SEMA6A,PITPNM2,SNX24,BLZF1,ARL1,FAM193A,ZNF542P,BCL2L2,ARHGEF7,RAB29,MPZL1,SLC5A8,PCCA,PDE4D,CENPC,VIT,MRPL57,CFAP54,POLN,AKAP6,TAPT1,GNPTAB,VCAN,FCRL5,COG3,DMXL1,WDR1,MEMO1,LATS2,MPHOSPH9,STK32B,POLK,SUCO,SELP,G2E3,NUBPL,SLC8A1,ARHGEF40,SLC22A4,SLC22A5,GABRA2,KIF21B,PDS5B,GAK,NAAA,CD244,NPAS3,MRPS27,CMPK2,NFASC,TBC1D1,ADGRL3,ANO4,ACSL6,XPO4,NCSTN,NT5C1B,LINC01551,ADAMTS19,GPN1,TECRL,TXK,GUF1,SLAIN1,HSD17B4,FCRL6,KCNT2,ZNF470,CCDC169,LHX9,FAM151B,LMLN,LAD1,LCP1,AXDND1,LOX" MicroRNA hsa-miR-20a:mirSVR_highEffct hsa-miR-20a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.03E-33 5.46E-30 3.10E-32 2.84E-31 90 1684 "MDM4,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,ARHGEF7,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,SNTG2,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,NUDT12,CEP120,SACS,RABGAP1L,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,LRPPRC,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,FGF9,RELL1,SUCO,FOXG1,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,NAAA,EAPP,ERAP1,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPARGC1A,BRD8,ARHGEF28,RNF17,AP4S1,RIMBP2,NPL,KLF12,GUF1,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,CDK2AP1,IFT88" MicroRNA hsa-miR-487a:mirSVR_highEffct hsa-miR-487a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-33 7.26E-30 4.10E-32 3.76E-31 71 1025 "MAP1B,SMIM15,NLN,ANKRD34B,BLZF1,ASTN1,SLC4A4,STARD13,NFKBIA,FCHO2,LDB2,SNTG2,ZMYM5,CDK17,PDE4D,RCBTB2,SNX6,PIK3C2B,BOD1L1,EPN1,CRHBP,LRRTM2,COG3,CEP350,C14orf119,DNMT3A,RASA1,TMEM161B,LATS2,DEPDC4,DRAM1,SAP18,USP44,GORAB,FGF9,SUCO,SCYL2,TADA1,CCDC88A,YPEL5,LIMCH1,KIF21B,NAAA,CD244,NPAS3,GC,ANKLE2,LRCH1,ERBIN,PPARGC1A,GJB2,PSME4,METAP2,ADGRL3,TEP1,MSH6,TENT2,NLRP8,YTHDC2,KCNT2,ZNF470,ANKS1B,ZMYM2,LHX9,TMEM178A,KCNN2,DIAPH3,KIT,TTC41P,CDK2AP1,LOX" MicroRNA hsa-miR-490-5p:mirSVR_lowEffct hsa-miR-490-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-33 8.83E-30 4.96E-32 4.54E-31 86 1545 "ADD1,ADORA1,SEMA6A,DHX37,PPFIA4,UVSSA,BLZF1,ASTN1,PPP1R12B,BCL2L2,LDB2,CD1E,UHMK1,PCDH9,FAM177A1,SCFD2,CDK17,PDE4D,GLT1D1,POLN,HOMER1,TAPT1,CEP135,PRKD1,NOS1AP,ZFYVE16,MATR3,G3BP2,RABGAP1L,FAM129A,TMEM33,RNASEL,LATS2,MBNL2,DCUN1D2,TRAPPC12,KLHL12,TBC1D19,STX2,CWC27,ELOVL7,UTP15,TNFRSF19,G2E3,MBIP,PAICS,SLC8A1,ARHGEF40,SLC12A2,FSHR,NR5A2,YPEL5,MYO16,JPH4,TMEM183A,NFASC,ANKLE2,IKBIP,LPIN1,GJA3,GOLGA3,ADGRL3,ACSL6,COP1,RNF17,CRB1,GPR161,LINC01551,RAB2B,RIMBP2,HEXB,ADAMTS19,TXK,RXFP2,SLAIN1,VRK2,YTHDC2,JCHAIN,SELENOI,ZMYM2,FAM151B,NPHS2,KCNN2,LINC00442,FAM71C,LIG4" MicroRNA hsa-miR-384:mirSVR_lowEffct hsa-miR-384:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-33 9.04E-30 5.05E-32 4.63E-31 92 1772 "MATN3,BIRC6,ATP6V1G3,EP400,BLZF1,ASTN1,ATP1A2,KCTD12,PPP1R12B,NOVA1,CDKL2,SNTG2,ZNF664,RGSL1,PDE4D,PDGFRA,SLC25A3,PKP1,LTB4R,HOMER1,AKAP6,FAM163A,FAM53A,LYSMD3,SNCAIP,LACC1,FAM169A,UBXN2A,FCRL5,DCAF8,COG3,FBXL5,OCIAD1,RABGAP1L,LINC01257,PARPBP,PPP2R3C,C14orf119,NR1H4,RASA1,FAM228A,TMEM33,SETDB2,RNASEL,LATS2,ELF1,TBC1D19,DNAJC27,PCGF3,POLK,SDC1,SUPT20H,VEZT,RUBCNL,SLC34A2,FBXO11,NBEA,PLEKHA6,UFM1,SLC12A2,C1orf112,FSHR,NMNAT2,IQGAP2,ERAP1,ATP8A2,GJB6,GC,MCCC2,LRCH1,LILRB1,IKBIP,KLHL20,TMED2,PPIP5K2,ADGRL3,GPR12,KMT5A,BAZ1A,TPO,ADAMTS19,HPCAL1,WDR36,ZNF10,KCNT2,CCDC169,ZMYM2,KCNJ9,LAD1,LIG4,IFT88,ZNF304" MicroRNA hsa-miR-130b:mirSVR_highEffct hsa-miR-130b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.75E-33 9.28E-30 5.16E-32 4.72E-31 82 1401 "MATN3,MDM4,BIRC6,KIAA1211,WDR35,ULK1,APAF1,BLZF1,WDR19,NCOA1,ATP12A,ZNF542P,STARD13,BTF3,DAOA,CDKL2,CAST,RILPL1,FAM177A1,PDGFRA,CFL2,JAKMIP1,HOMER1,AKAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,DNM3,PRKD1,DCAF8,SREK1,PTGS2,FBXL5,CEP120,PARPBP,RASA1,AASDH,MEMO1,PACRGL,ELK3,MPHOSPH9,SAP18,CLIP1,F10,NDUFAF7,GORAB,N4BP2L2,TNFRSF19,PEAR1,FLT1,NBEA,SLC8A1,CCDC88A,WDCP,C1orf112,MEGF10,MYT1L,KDM5B,ZNF274,ERAP1,CMPK2,LRCH1,ERBIN,KLHL20,NPFFR2,INSM2,RNF17,NPL,ADAMTS19,UBC,SLAIN1,TENT2,C12orf73,IRF1,FAM49A,LMLN,CAB39L,DIAPH3,RMST,LIG4,LMNB1" MicroRNA hsa-miR-25:mirSVR_lowEffct hsa-miR-25:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-33 1.10E-29 6.07E-32 5.56E-31 91 1738 "SFTA3,CUL4A,APBB2,DDX55,BLZF1,ARL1,AACS,NCOA1,ASTN1,ATP1A2,SLC4A4,ATP7B,NRL,CAMK4,RILPL1,SLC5A8,PCDH9,FAM177A1,XPR1,CDK7,PDE4D,PDGFRA,SLC25A3,SMIM14,PITX1,HOMER1,EPGN,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SPATA18,SREK1,LOC439933,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DTD2,CLIP4,POLR1D,LGR6,TBC1D19,GP6,FAM172A,DEPDC4,ARSK,STK32B,DNAJC27,FCAR,GORAB,RELL1,FOXG1,RASA3,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,NMNAT2,CMPK2,ERBIN,IKBIP,STRN,MAST4,ADAM17,PPIP5K2,EML4,KMT5C,COX18,RNF17,LINC01551,ADAMTS19,TRPC4,HMGCR,TMEM174,VRK2,YTHDC2,ZNF470,IRF1,TMEM178A,LAD1,SPATA13" MicroRNA hsa-miR-640:mirSVR_lowEffct hsa-miR-640:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-33 1.24E-29 6.80E-32 6.22E-31 79 1301 "RALGAPA1,ABL2,WDR35,HOMEZ,NCOA1,ATP4B,CD84,ARHGEF7,BTF3,AP1G2,ADGRD1,PNP,MPZL1,FCGR2C,DCLK1,PCSK1,PDGFRA,WDFY2,ITGBL1,JAKMIP1,C1orf116,RCHY1,PM20D1,CMTM5,CEP350,PARPBP,NR1H4,DNMT3A,RGS12,TMEM33,CRYL1,SETDB2,MBNL2,TRAPPC12,SNORA53,GP6,ARSK,ELOVL7,PCBD2,TMEM156,FNIP1,POLK,SUCO,FLT1,SLC34A2,NUBPL,THADA,ARHGEF40,TMEM132D,SLC22A5,MYT1L,PDS5B,KDM5B,NMNAT2,NPAS3,ZBTB37,LPIN1,ATP11A,METAP2,ARHGEF28,KHNYN,RNF212,RNF17,SLC7A8,GTF3C2,RAB2B,TMPO,NPL,ADAMTS19,WDR36,STARD4,TADA2B,PLB1,LHX9,FAM151B,CAB39L,RILPL2,TTC41P,SPATA13" MicroRNA hsa-miR-188-3p:mirSVR_lowEffct hsa-miR-188-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-33 1.25E-29 6.85E-32 6.27E-31 95 1897 "MDM4,NDRG2,NYNRIN,PPFIA4,APBB2,MSH2,AACS,ZNF542P,NFATC4,ARHGEF7,PNP,CBLN3,CDKL2,LDB2,XPR1,SCFD2,GLT1D1,PDE6B,CHD1,PFKFB2,MRPL57,LINC01085,POLN,HECTD1,THAP6,RNASE9,C12orf65,ITSN2,LRRTM2,KIAA0040,SREK1,COG3,SLC35F6,WDR1,TSEN15,FAM129A,RASA1,AASDH,FAM228A,POLR1D,PACRGL,EFNA5,MBNL2,FCAMR,PCGF3,CLIP1,F7,PCBD2,FCAR,FCGR3A,TOMM40L,FCGR3B,LRRN2,TNFRSF19,FOXG1,FLT3,STAB2,DDX51,NUBPL,STPG4,THADA,SLC12A2,TMEM132D,WDCP,ZNF667,CHFR,DCAF11,SNRPF,RAPGEF6,ATP8A2,GCKR,NEDD1,MAST4,ARHGEF28,STON1,DOCK9,TDG,RNF17,TFDP1,LINC01551,MAEL,ATP6V0A2,HPCAL1,PAPPA2,WDR36,NSD2,DCP2,IGF1,KCNJ9,LINC01913,LINC00442,NUAK2,TTC7A,PABPN1,ZNF304" MicroRNA hsa-miR-148a*:mirSVR_highEffct hsa-miR-148a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-33 1.35E-29 7.31E-32 6.69E-31 86 1554 "ABL2,ATP6V1G3,ANKRD34B,MIPEP,ARL1,STARD13,NOVA1,CDKL2,MPZL1,FCHO2,CDK17,PDGFRA,LINC01085,ATAD2B,HECTD1,TAPT1,GNPTAB,PM20D1,SYCP3,SNCAIP,FAM169A,UBXN2A,MATR3,PSME1,SREK1,COG3,FBXL5,LOC439933,PTPRC,G3BP2,RABGAP1L,PXMP2,TSEN15,RB1,SLC9C2,LAP3,RGS12,MEMO1,EIF2D,DCUN1D2,SPATA9,ELF1,ELK3,CWC27,ETF1,CLIP1,TRAPPC13,NDUFAF7,FNIP1,N4BP2L2,RELL1,FOXO1,FLT1,FTLP10,TM9SF1,NBEA,THADA,CCDC88A,PKD2L2,CGREF1,CYP1B1-AS1,MEGF10,GABRB1,PDS5B,TMEM183A,IQGAP2,ERAP1,CMPK2,IKBIP,PPARGC1A,ADGRL3,TEP1,NT5C1B,CRB1,ZBTB49,HMGCR,SLAIN1,PAPPA2,ZMYM2,TMEM178A,KCNN2,KIR2DS4,LETM1,AXDND1,PABPN1,MICU2" MicroRNA hsa-miR-219-5p:mirSVR_lowEffct hsa-miR-219-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.72E-33 1.44E-29 7.81E-32 7.15E-31 76 1201 "RALGAPA1,SFTA3,ATP6V1G3,COG6,AACS,ATP1A2,BTF3,NOVA1,NRL,AMDHD1,CHAMP1,NFXL1,PDE4D,CFL2,CCDC122,VIT,BOD1L1,HOMER1,STRN3,GNPTAB,HEATR5A,SNCAIP,CEP135,DNM3,KIAA0040,UBXN2A,GLT8D2,PIGG,SREK1,COG3,DMXL1,FBXL5,TBC1D4,PTPRC,G3BP2,PPP2R3C,SMC6,SLC9C2,RGS12,MEMO1,RNASEL,ELK3,PCGF3,SLC22A17,GORAB,FGF9,PIBF1,POLK,MROH9,HSD17B7,VEZT,IVNS1ABP,THADA,CCDC88A,PKD2L2,ZNF667,YPEL5,SNRPF,NAAA,UHRF1BP1L,NFASC,KLHL20,PCDH17,MTUS2,RNF212,RNF17,CRB1,TXK,GUF1,ZNF876P,NSD2,ZNF84,IL6ST,ANKS1B,LHX9,LOX" MicroRNA hsa-miR-18a:mirSVR_lowEffct hsa-miR-18a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.23E-33 1.72E-29 9.23E-32 8.45E-31 88 1634 "TMEM132B,SEMA6A,PPFIA4,BLZF1,ARHGAP5,FAM193A,ASTN1,ATP12A,ZNF542P,ATP4B,KCTD12,LINC02347,NOVA1,PNP,NRL,AMDHD1,MORN2,LDB2,RFLNA,PCDH9,CDK18,RGSL1,PIWIL1,PFKFB2,WDFY2,SNX6,PTPRVP,CLOCK,C12orf65,FCRL5,DCAF8,PTPRC,EGLN3,RASA1,SMC6,RGS4,RGS12,MBNL2,KIRREL1,LGR6,DRAM1,CLIP1,FCAR,UTP15,NDUFAF7,GORAB,FGFR3,FLT1,STAB2,RUBCNL,G2E3,NBEA,DDX51,PLEKHA6,UFM1,TADA1,CCDC88A,SF3B6,ACIN1,CYP1B1-AS1,MYO16,GABRB1,ANKLE2,LRCH1,SULT1E1,STRN,ADGRA3,RIPK3,CRB1,RAB2B,TMPO,ADAMTS19,UBE2K,GUF1,HTR2A,ZNF84,CCDC169,PLB1,SPTSSA,FAM49A,KCNN2,KIT,TTC41P,LETM1,FAM71C,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-182:mirSVR_highEffct hsa-miR-182:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.53E-33 1.88E-29 1.01E-31 9.20E-31 88 1636 "MATN3,BIRC6,NYNRIN,WDR35,SNX24,RGS5,APC,NCOA1,ATP1A2,STARD13,MYH6,ARHGEF7,CACNA1E,MORN2,CHAMP1,SLC5A8,ZNF664,PCK2,RGSL1,PDE4D,PDGFRA,PIWIL1,PGGT1B,COLEC11,LINC01085,BOD1L1,THAP6,HOMER1,PMCH,TAPT1,POU2F1,CLOCK,PREPL,CSNK1G3,CEP135,PRKD1,SREK1,DMXL1,NUDT12,TBC1D4,OCIAD1,SACS,SUPT7L,PARPBP,RASA1,SMC6,AASDH,MBNL2,ARSK,ABCA11P,PCGF3,GORAB,RELL1,HSD17B7,FTLP10,VEZT,BRMS1L,IVNS1ABP,NR5A2,LIMCH1,MYT1L,PDS5B,KDM5B,GJB6,OXGR1,RBKS,MCCC2,NEDD1,LRCH1,ZBTB37,UGT2A1,ADGRL3,EML4,DOCK9,RNF212,GTF3C2,ZNF721,TNR,KLF12,ARHGAP30,LTB4R2,STARD4,SPTSSA,GALP,DIAPH3,RMST,AXDND1,LOX" MicroRNA hsa-miR-221:mirSVR_lowEffct hsa-miR-221:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.84E-33 2.04E-29 1.09E-31 9.94E-31 85 1526 "MDM4,TMEM132B,SLAMF6,CUL4A,MCFD2,MSH2,ASTN1,CCNB1IP1,SLC4A4,ATP2B4,NFATC4,ARHGEF7,NRL,MPZL1,RILPL1,MORN2,PCDH9,CDK7,PCSK1,PDGFRA,GLT1D1,VIT,WDFY2,NRXN1,AKAP6,MPC2,FAM163A,CRHBP,LRRTM2,DNM3,UBXN2A,FCRL5,MATR3,SPATA18,LOC439933,OCIAD1,GNPDA2,FAM129A,TMEM161B,FAM228A,DTD2,LAP3,RGS12,RNF4,ELF1,MPHOSPH9,STX2,ARSK,FOXG1,FLT1,STAB2,G2E3,THADA,CGREF1,MRPS14,CHFR,MYO16,GABRB1,KDM5B,GJB6,KDM3B,SRP72,KLHL20,MAST4,ADGRL3,GPR12,RNF212,RNF17,CRB1,GPR161,LINC01551,BAZ1A,ADAMTS19,KLF12,UBE2K,POC5,NSD2,IGF1,ZNF140,ANKS1B,ZMYM2,ZBTB41,ANKDD1B,AMTN,SKA3" MicroRNA hsa-miR-1271:mirSVR_lowEffct hsa-miR-1271:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.97E-33 2.11E-29 1.12E-31 1.02E-30 87 1601 "MDM4,BIRC6,SEMA6A,SNX24,RGS5,PPFIA4,APBB2,APC,ATP1A2,STARD13,PPP1R12B,CBLN3,MORN2,CHAMP1,CD1D,SCARB1,PAH,PCCA,PCDH9,CDK18,PDGFRA,WDFY2,NRXN1,BOD1L1,HEATR5A,CLOCK,CEP135,PRKD1,ZFYVE16,PIGG,COG3,DMXL1,CEP350,SACS,PPP2R3C,GALNT14,ATG10,RASA1,RB1,AASDH,CLIP4,CRYL1,LRPPRC,MBNL2,LGR6,MAEA,ETF1,ABCA11P,PCGF3,FCAR,N4BP2L2,SUCO,MROH9,BRMS1L,ARHGEF40,TADA1,CCDC88A,SLC12A2,CGREF1,LIMCH1,DCAF11,CYP1B1-AS1,NPAS3,DRC1,PCDH17,UGT2A1,ADGRL3,ANO4,DOCK9,TEP1,SLC7A8,TMPO,TNR,ADAMTS19,KLF12,GPN1,TECRL,MZF1,ZNF470,SELENOI,ZMYM2,ZBTB41,KIF2A,TTC41P,SLAMF9,AXDND1,LOX" MicroRNA hsa-miR-339-5p:mirSVR_lowEffct hsa-miR-339-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.02E-33 2.14E-29 1.13E-31 1.03E-30 85 1527 "EP400,PPFIA4,APAF1,ZNF542P,NLRP4,B4GALT3,BTF3,LINC02347,PNP,CD1E,SNTG2,PDE4D,PDGFRA,GLT1D1,CHD1,THAP6,FAM163A,GNPTAB,NCOR2,SNCAIP,CSNK1G3,UBXN2A,COG3,F11R,SLC35F6,PARPBP,EGLN3,DTD2,TXNDC15,RNF4,LGR6,DHRS2,TCTN2,GP6,DRAM1,ARSK,STK32B,F7,SLC22A17,F10,ELOVL7,FCAR,FCGR2B,NDUFAF7,N4BP2L2,TACC3,PIBF1,SDC1,FLT1,PAICS,SLC12A2,POTEM,CGREF1,EFR3B,UGGT2,NPAS3,MCCC2,ANKLE2,LRCH1,ERBIN,STRN,MAST4,METAP2,ADGRL3,ACSL6,DOCK9,KHNYN,COP1,TFDP1,RASSF6,RAB2B,ATP6V0A2,ARHGAP30,PLB1,SPTSSA,ZBTB41,ZBED3-AS1,KCNN2,FIP1L1,RNASE11,TTC41P,LAD1,MFSD2B,RMST,NUAK2" MicroRNA hsa-miR-3171:mirSVR_lowEffct hsa-miR-3171:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-33 2.19E-29 1.14E-31 1.05E-30 94 1871 "SMIM15,MDM4,KIAA1211,ATP6V1G3,WDR35,SNX24,APAF1,BLZF1,ADGRD1,GAS2L3,CD1E,UHMK1,PAH,SLC5A8,PCDH9,ZMYM5,CHD1,WDFY2,SNX6,C1orf116,AKAP6,STRN3,TAPT1,LYSMD3,CRHBP,KIAA0040,PRKD1,DDX59,ZFYVE16,BIVM,DGKQ,COG3,NUDT12,OCIAD1,GNPDA2,MTX3,NR1I3,DNMT3A,ATG10,RASA1,ARGLU1,RGS4,EFNA5,MBNL2,GP6,EFS,CWC27,ETF1,USP44,TRAPPC13,SUCO,FOXO1,HSD17B7,FTLP10,SUPT20H,ZCCHC8,IVNS1ABP,SLC8A1,SLC12A2,PKD2L2,POTEM,SF3B6,SLC22A4,NAAA,UHRF1BP1L,CMPK2,SRP72,MCCC2,IKBIP,PCDH17,PPARGC1A,GJB2,ZNF544,ADGRL3,ANO4,CRB1,LINC01551,ACTR6,HAL,ADAMTS19,HSP90B1,UBE2K,TMEM174,SLAIN1,ZNF876P,TENT2,STARD4,IGF1,ZNF140,ZBTB41,KIT,DNAH10,SPRYD7,TTC7A" MicroRNA hsa-miR-4261:mirSVR_highEffct hsa-miR-4261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.62E-33 2.46E-29 1.28E-31 1.17E-30 88 1642 "RALGAPA1,MAP1B,MCC,MDM4,HOMEZ,CUL4A,ATP4B,FCRL3,BTF3,SLC5A6,ADGRD1,CAST,CHAMP1,UHMK1,SNTG2,ZMYM5,PCSK1,CDK17,RGSL1,PDE4D,PDGFRA,VIT,CLOCK,SNCAIP,CEP135,FAM169A,DNM3,FCRL5,EIF2AK2,IFT172,BIVM,COG3,FBXL5,NUDT12,G3BP2,PARPBP,TSEN15,GALNT14,RB1,TMEM161B,SLC9C2,TXNDC15,RNF4,MBNL2,FAM172A,DRAM1,ABCA11P,TMEM156,GORAB,RELL1,SDC1,FOXO1,BRMS1L,IVNS1ABP,GABRA2,PDS5B,GAK,JPH4,NAAA,CD244,HSPH1,OXGR1,KDM3B,CMPK2,SRP54,PSME4,UGT2A1,SCFD1,ADGRA3,GPR12,EML4,TFDP1,GTF3C2,ACTR6,TMPO,HEXB,GUF1,HSD17B4,ZNF876P,TENT2,VRK2,CCDC169,PLB1,FAM151B,NPHS2,ZBED3-AS1,RMST,PABPN1" MicroRNA hsa-miR-192*:mirSVR_lowEffct hsa-miR-192*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-33 2.60E-29 1.35E-31 1.23E-30 81 1386 "ABL2,ACOX3,CDKL4,ARHGAP5,AACS,ZNF542P,KCTD12,BCL2L2,NOVA1,CACNA1E,CD1D,ZNF664,CDK7,CDK18,PDGFRA,CFL2,SLC25A3,TM9SF2,POLN,HECTD1,PTPRVP,HOMER1,STRN3,FAM163A,TOGARAM2,PREPL,SNCAIP,LACC1,DNM3,UBXN2A,ZNF586,SNX17,COG3,LOC439933,NUDT12,TBC1D4,GNPDA2,DNMT3A,TMEM161B,OGFOD2,POLR1D,RNASEL,ELK3,ARSK,TOMM40L,FNIP1,SDC1,FLT3,PLEKHA6,TADA1,SLC15A4,SLC22A4,YPEL5,EFR3B,KIF21B,KDM5B,TMEM183A,CD244,HSPH1,DRC1,KLHL20,LPIN1,ADGRL3,ADGRA3,TEP1,CRB1,TMPO,RIMBP2,TPO,ADAMTS19,UBE2K,VRK2,ZNF10,MZF1,IL6ST,IRF1,CHPT1,KCNN2,EP400P1,TTC41P,LETM1" MicroRNA hsa-miR-34b:mirSVR_lowEffct hsa-miR-34b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-33 2.73E-29 1.41E-31 1.29E-30 93 1837 "SFTA3,SMIM15,TMEM132B,WDR35,NFATC4,CDKL2,TAF1B,AMDHD1,FCHO2,PCDH9,DCLK1,ZMYM5,XPR1,CDK7,CFL2,PFKFB2,WDFY2,TM9SF2,SMIM14,SNX6,ATAD2B,THAP6,LYSMD3,CRHBP,LACC1,CEP135,FAM169A,DNM3,MPHOSPH8,EIF2AK2,NOS1AP,IFT172,SPATA18,FBXL5,LOC439933,NUDT12,TBC1D4,OCIAD1,F11R,FAM129A,RB1,SMC6,RGS12,CRYL1,LRPPRC,PACRGL,EFNA5,RNF4,MARVELD2,DLEU1,ADGRV1,USP44,PCBD2,GORAB,SUCO,PEAR1,FLT1,FLT3,FTLP10,NBEA,THADA,C1orf112,SF3B6,LIMCH1,MEGF10,JPH4,IQGAP2,HSPH1,NPAS3,SRP54,SRP72,MCCC2,PPARGC1A,GJA3,PPIP5K2,ACSL6,EML4,DOCK9,GRSF1,TMPO,ATP6V0A2,HMGCR,GUF1,IL6ST,ZNF140,CCDC190,ZBTB41,LMLN,RILPL2,LINC00442,AXDND1,LTA4H,SPATA13" MicroRNA hsa-miR-411*:mirSVR_lowEffct hsa-miR-411*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.97E-33 3.18E-29 1.63E-31 1.49E-30 97 2000 "MATN3,BIRC6,ADD1,SLAMF6,ATP6V1G3,WDR35,CUL4A,FBRSL1,APC,BLZF1,ZNF542P,KCTD12,NOVA1,TAF1B,CAST,AMDHD1,FCHO2,CHAMP1,NFXL1,PCCA,PDE4D,PDGFRA,ATAD2B,CFAP45,BOD1L1,AKAP6,COPA,PREPL,VCAN,FCRL5,EIF2AK2,NOS1AP,GLT8D2,MATR3,DMXL1,FBXL5,TBC1D4,PTPRC,GNPDA2,RNF219,NR1H4,FAM228A,RGS4,DCUN1D2,SPATA9,UGT2A3,ELF1,MARVELD2,BORA,STK32B,ETF1,DNAJC27,GORAB,FGFR3,PEAR1,FLT3,FTLP10,ZCCHC8,G2E3,UFM1,GFM2,SCYL2,CCDC88A,ZNF605,SLC22A5,YPEL5,LIMCH1,MYO16,MEGF10,MYT1L,UHRF1BP1L,LRCH1,KLHL20,LPIN1,MAST4,PSME4,UGT2A1,TMED2,TDG,COX18,TFDP1,RASSF6,MAEL,HEXB,HSP90B1,UBE2K,GPN1,VRK2,JCHAIN,TADA2B,FAM151B,FAM49A,KIT,SPRYD7,LIG4,LMNB1,MICU2" MicroRNA hsa-miR-4329:mirSVR_lowEffct hsa-miR-4329:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.89E-33 4.73E-29 2.41E-31 2.21E-30 91 1772 "NDRG2,ADD1,KIAA1211,ATP6V1G3,WDR35,HOMEZ,MSH2,ARL1,ASCL1,SLC4A4,ZNF542P,KCTD12,BCL2L2,ARHGEF7,LINC02347,DAOA,CACNA1E,CDK7,SLC25A3,ITGBL1,JAKMIP1,PTPRVP,AKAP6,POU2F1,PREPL,DNM3,OCIAD1,DHFR,TSEN15,GALNT14,B3GLCT,AASDH,RGS12,POLR1D,NTN4,LRPPRC,PACRGL,RNASEL,LATS2,MBNL2,ELF1,ARSK,CWC27,ABCA11P,SLC22A17,TMEM129,RELL1,PIBF1,SUPT20H,GOLGA2P5,TM9SF1,G2E3,NBEA,ALKAL2,IVNS1ABP,SLC8A1,TMEM132D,N4BP2,MEGF10,ALLC,RAPGEF6,ZNF274,HSPH1,MRPS27,CMPK2,NFASC,MCCC2,IKBIP,KLHL20,GJA3,ADGRL3,GPR12,EML4,TDG,CRB1,TGFBI,LINC01551,RIMBP2,NPL,HMGCR,HTR2A,KCNT2,ZNF324B,SDR39U1,ZBED3-AS1,CHPT1,LMLN,TTC41P,LAD1,LCP1,LETM1" MicroRNA hsa-miR-579:mirSVR_highEffct hsa-miR-579:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.71E-33 5.17E-29 2.62E-31 2.40E-30 94 1892 "RALGAPA1,MAP1B,SMIM15,IL17D,MDM4,SLAMF6,COG6,HOMEZ,CUL4A,UVSSA,APAF1,APC,ARHGAP5,NOP14,STXBP6,PPP1R12B,ARHGEF7,NOVA1,AMDHD1,LDB2,SCARB1,ZNF664,PDE4D,PDGFRA,WDFY2,ITGBL1,STRN3,TAPT1,COPA,CLOCK,LACC1,LRRTM2,FCRL5,BIVM,SPATA18,PTGS2,CEP120,F11R,RABGAP1L,GNPDA2,SUPT7L,PARPBP,TSEN15,IPO4,SLC9C2,DHRS2,DRAM1,CWC27,SAP18,MAEA,TRAPPC13,TMEM129,NDUFAF7,FNIP1,FMO1,VEZT,ZCCHC8,NBEA,UFM1,IVNS1ABP,THADA,SLC22A4,NR5A2,UGGT2,GABRA2,PDS5B,IQGAP2,ERAP1,NPAS3,KDM3B,SRP72,ERBIN,IKBIP,PCDH17,PPARGC1A,PPIP5K2,ANO4,C5orf56,RNF17,TMPO,FZD10,NPL,HEXB,TECRL,GUF1,IL6ST,CCDC190,ZMYM2,FAM151B,KCNN2,RNASE11,TTC41P,SPRYD7,AXDND1" MicroRNA hsa-miR-4302:mirSVR_lowEffct hsa-miR-4302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-32 6.06E-29 3.06E-31 2.80E-30 96 1976 "RALGAPA1,MAP1B,MCC,MDM4,NDRG2,NLN,SEMA6A,PITPNM2,WDR19,ASCL1,ASTN1,FGFRL1,BCL2L2,CD84,PROZ,ODC1,CD1D,CDK7,PDGFRA,CENPC,PDE6B,CHIT1,ITGBL1,AKAP6,COPA,POU2F1,PRKD1,DCAF8,ZFYVE16,PIGG,SREK1,TINF2,RABGAP1L,LINC01257,ZNF329,SLC9C2,CLIP4,ZNF419,LRPPRC,PACRGL,TXNDC15,LATS2,DHRS2,GP6,ARSK,PCGF3,CLIP1,SH3YL1,TRAPPC13,IRF9,NDUFAF7,SPON2,GORAB,RELL1,POLK,SUCO,FOXO1,HSD17B7,STAB2,SGCG,RUBCNL,G2E3,CCDC92,MBIP,ARHGEF40,PKD2L2,DCAF11,MYO16,HSPH1,KDM3B,TBC1D1,GOLGA3,ANO4,KMT5A,TFDP1,CRB1,TGFBI,ZBTB49,AP4S1,TNNT2,TNR,ADAMTS19,TECRL,TXK,ZNF550,SLAIN1,HSD17B4,HTR2A,STARD4,NSD2,YTHDC2,ZNF26,PLB1,LINC00272,KIF3C,AXDND1" MicroRNA hsa-miR-361-5p:mirSVR_lowEffct hsa-miR-361-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-32 7.13E-29 3.58E-31 3.27E-30 88 1666 "KIAA1211,NLN,COG6,MIPEP,EP400,APBB2,BLZF1,ARL1,NCOA1,ASTN1,CENPBD1P1,SLC4A4,ZNF542P,NOVA1,CACNA1E,CHAMP1,LDB2,UHMK1,SNTG2,SLC5A8,ZNF664,PCCA,XPR1,CDK7,SCFD2,PDE4D,CENPC,GLT1D1,CFL2,VIT,SLC25A3,GPR180,MRPL57,ADGRF3,STRN3,RCHY1,LYSMD3,LACC1,DDX59,ZFYVE16,MATR3,FBXL5,GNPDA2,PARPBP,NR1H4,TMEM33,CLIP4,RNASEL,LATS2,ELF1,STK32B,FNIP1,TNFRSF19,PIBF1,FLT1,BRMS1L,GFM2,TADA1,SLC12A2,C1orf112,CHFR,GABRB1,PDS5B,ERAP1,OXGR1,KDM3B,CMPK2,PCDH17,GJA3,MTUS2,LILRB4,ACSL6,DOCK9,RNF212,FCRLA,TFDP1,SLC7A8,GTF2H3,RASSF6,MAEL,TECRL,TXK,TMEM174,NSD2,ZNF84,PLB1,LOX,ZNF304" MicroRNA hsa-miR-200a:mirSVR_highEffct hsa-miR-200a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.34E-32 7.15E-29 3.58E-31 3.27E-30 85 1553 "SMIM15,MDM4,ADD1,BLZF1,ASTN1,KCTD12,BTF3,TAF1B,CAST,PCDH9,XPR1,CDK7,CDK17,CFL2,CHD1,WDFY2,SLC25A3,COLEC11,ATAD2B,EPN1,HECTD1,STRN3,GNPTAB,HEATR5A,LYSMD3,PREPL,LACC1,CSNK1G3,VCAN,DNM3,PRKD1,DDX59,SPATA18,SREK1,COG3,NUDT12,CEP120,WDR1,PARPBP,RB1,CRYL1,LATS2,STX2,FAM172A,CWC27,STK32B,PCGF3,CLIP1,FNIP1,PIBF1,SUCO,FLT1,SUPT20H,VEZT,ALKAL2,UFM1,TADA1,CCDC88A,YPEL5,LIMCH1,MEGF10,GABRA2,MYT1L,PDS5B,NPAS3,LRCH1,COMMD6,PPARGC1A,STRN,ZNF544,GOLGA3,ADGRL3,GPR12,YIPF7,FCRLA,LINC01551,RAB2B,HEXB,TENT2,VRK2,HTR2A,KCNT2,ANKS1B,CHPT1,LOX" MicroRNA hsa-miR-3159:mirSVR_lowEffct hsa-miR-3159:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-32 7.27E-29 3.62E-31 3.31E-30 82 1443 "MDM4,TMEM132B,NLN,ANKRD34B,APAF1,MSH2,BLZF1,ASTN1,ATP2B4,RAB29,CD1E,SCARB1,FCRLB,ZMYM5,RGSL1,PDE4D,WDFY2,SMIM14,ATAD2B,HECTD1,HEATR5A,NGDN,SNCAIP,CSNK1G3,LRRTM2,FAM169A,FCRL5,ZNF586,PIGG,DCT,RABGAP1L,NR1I3,ARGLU1,TMEM161B,ZNF329,DTD2,CRYL1,PACRGL,RNASEL,UGT2A3,ELF1,GP6,FAM172A,DNAJC27,GMPR2,PCGF3,SH3YL1,PCBD2,FCGR3A,UTP15,TOMM40L,FCGR3B,FLT1,TM9SF1,FBXO11,SLC30A6,ARHGEF40,ZNF605,MRPS14,LIMCH1,GABRA2,KDM5B,NPAS3,KLHL20,INSM2,METAP2,ADGRA3,DOCK9,XPO4,TDG,GRSF1,CRB1,BAZ1A,RAB2B,HEXB,TECRL,TXK,GUF1,TENT2,PAPPA2,ZMYM2,MFSD2B" MicroRNA hsa-miR-205:mirSVR_lowEffct hsa-miR-205:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-32 7.38E-29 3.65E-31 3.34E-30 96 1981 "ADD1,ADORA1,WDR35,ZNF784,NCOA1,SLC4A4,ZNF542P,STARD13,RILPL1,UHMK1,ZNF664,PCDH9,DCLK1,PCSK1,CDK17,RCBTB2,CCDC122,SLC25A3,TM9SF2,SMIM14,ADGRF3,THAP6,AKAP6,PREPL,SNCAIP,TTC37,LRRTM2,FBXL5,NUDT12,PTPRC,RASA1,SMC6,CLIP4,NTN4,LRPPRC,STX2,GP6,ARSK,SAP18,DLEU1,USP44,TRAPPC13,SUCO,STAB2,RASA3,ALKAL2,UFM1,SCYL2,TADA1,ZNF605,SLC12A2,PKD2L2,POTEM,GABRA2,GABRB1,PDS5B,CENPJ,NAAA,IQGAP2,ERAP1,ATP8A2,SRP72,DRC1,ANKLE2,MAST4,PPIP5K2,MTUS2,ANO4,ARHGEF28,XPO4,TDG,RNF17,TEP1,TFDP1,GTF3C2,ACTR6,TPO,ADAMTS19,GUF1,VRK2,HTR2A,NSD2,IGF1,ZNF84,C12orf73,IL6ST,LHX9,FIP1L1,KIF2A,SLAMF9,LETM1,NUAK2,AXDND1,CDK2AP1,IFT88,PABPN1" MicroRNA hsa-miR-620:mirSVR_lowEffct hsa-miR-620:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-32 7.45E-29 3.67E-31 3.36E-30 88 1667 "MCC,MDM4,KIAA1211,COG6,WDR35,SEMA6A,RGS5,MSH2,ARHGAP5,ASTN1,CD84,BTF3,RAB29,NOVA1,RILPL1,RGSL1,PFKFB2,HECTD1,PTPRVP,THAP6,TOGARAM2,POU2F1,CLOCK,PREPL,SNCAIP,DNM3,UBXN2A,PRKD1,ZFYVE16,SNX17,DMXL1,LOC439933,KLHL3,TBC1D4,PTPRC,OCIAD1,F11R,FAM129A,B3GLCT,OGFOD2,GUSBP3,PCGF3,SLC22A17,ELOVL7,TRAPPC13,PCBD2,FCGR3A,FGF9,RELL1,PIBF1,SUCO,FOXO1,FMO1,RUBCNL,BRMS1L,NR5A2,ZNF667,CIDEB,KIF21B,UHRF1BP1L,ERAP1,ATP8A2,MCCC2,SULT1E1,GJA3,BRD8,TMED2,PPIP5K2,GOLGA3,ARHGEF28,COX18,FZD10,RIMBP2,MAEL,HAL,NPL,TPO,ARHGAP30,TECRL,WDR36,ZNF10,JCHAIN,FAM151B,NPHS2,CHPT1,KCNJ9,KCNN2,TTC41P" MicroRNA hsa-miR-130a:mirSVR_lowEffct hsa-miR-130a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-32 7.49E-29 3.67E-31 3.36E-30 90 1744 "MAP1B,MCC,ADD1,NLN,PITPNM2,RGS5,APBB2,ZNF784,WDR19,ASCL1,CENPBD1P1,ATP1A2,SLC4A4,MYH6,AP1G2,NOVA1,UHMK1,PDE4D,CEBPE,CHD1,PKP1,HECTD1,STRN3,TAPT1,HEATR5A,ITSN2,LRRTM2,FAM169A,MATR3,SNX17,COG3,KLHL3,G3BP2,WDR1,PPP2R3C,RNF219,EGLN3,FAM129A,OGFOD2,CLIP4,LRPPRC,RNASEL,EFNA5,GRTP1,ELF1,DHRS2,ZNF671,TNFRSF19,FOXG1,HSD17B7,STAB2,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,TMEM183A,ZNF274,IQGAP2,GJB6,RBKS,NEDD1,PCDH17,COMMD6,PPARGC1A,ATP11A,ADGRA3,GPR12,ARHGEF28,DOCK9,TGM1,LINC01551,RIMBP2,ATP6V0A2,NPL,TPO,HSP90B1,RXFP2,NSD2,IGF1,ZMYM2,ZBTB41,LHX9,FAM151B,KCNN2,KIT,TTC7A,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-532-5p:mirSVR_lowEffct hsa-miR-532-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-32 7.68E-29 3.73E-31 3.42E-30 89 1706 "COG6,RGS5,APBB2,MSH2,ARHGAP5,ARL1,AACS,STARD13,FGFRL1,NEDD8,DAOA,MPZL1,CHAMP1,UHMK1,SNTG2,XPR1,CDK7,PDE4D,PDGFRA,GLT1D1,CHIT1,WDFY2,SNX6,THAP6,EPGN,LYSMD3,BRI3BP,LACC1,ITSN2,FAM169A,DNM3,PRKD1,FCRL5,DDX59,ZNF586,ZFYVE16,PIGG,KLHL3,PTPRH,C14orf119,TSEN15,RNF219,RGS4,RGS12,TMEM33,SETDB2,MBNL2,ELK3,MPHOSPH9,GMPR2,PCBD2,UFM1,THADA,TADA1,SLC12A2,SLC15A4,N4BP2,EFR3B,KDM5B,EAPP,MRPS27,KDM3B,CMPK2,SRP72,MCCC2,KLHL20,MTUS2,CNTN2,XPO4,AP4S1,MAEL,ADAMTS19,TRPC4,ZNF550,SLAIN1,WDR36,ZNF470,PLB1,ANKS1B,ZBTB41,LHX9,CHPT1,KCNJ9,KIF3C,KIR2DS4,KIR3DL2,TTC41P,AXDND1,LMNB1" MicroRNA hsa-miR-526b*:mirSVR_highEffct hsa-miR-526b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-32 7.69E-29 3.73E-31 3.42E-30 86 1592 "MDM4,BIRC6,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,CD1E,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,POU2F1,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,SPATA18,PIGG,FBXL5,CEP120,SACS,G3BP2,GNPDA2,RNF219,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,GMPR2,USP44,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,ERAP1,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPIP5K2,ADGRL3,ARHGEF28,TEP1,AP4S1,RIMBP2,NPL,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,IFT88" MicroRNA hsa-miR-144*:mirSVR_lowEffct hsa-miR-144*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-32 7.81E-29 3.78E-31 3.46E-30 83 1481 "RALGAPA1,SFTA3,NLN,ANKRD34B,COG6,RGS5,FBRSL1,MSH2,ATP2B4,CD1E,NFXL1,FCRLB,SNTG2,SLC5A8,DCLK1,PCK2,PDGFRA,CENPC,CCDC122,ZNF595,SLC25A3,ADGRF3,HOMER1,PMCH,RCHY1,LRRTM2,DNM3,FCRL5,FCRL2,KLHL3,PTPRC,SACS,PPP2R3C,LATS2,DCUN1D2,UGT2A3,ELK3,MARVELD2,STX2,ETF1,DNAJC27,PCBD2,UTP15,SULT6B1,N4BP2L2,POLK,STAB2,NBEA,BRMS1L,ALKAL2,MBIP,UFM1,SLC12A2,PKD2L2,SLC22A4,TMEM183A,HSPH1,MIMT1,SULT1E1,PPARGC1A,GJB2,PPIP5K2,GOLGA3,ADGRA3,ACSL6,STON1,NT5C1B,ADAMTS19,TMEM174,HSD17B4,TENT2,VRK2,HTR2A,WDR36,STARD4,ZNF10,SELENOI,FAM151B,DIAPH3,AMTN,LINC01913,AXDND1,ZNF304" MicroRNA hsa-miR-618:mirSVR_lowEffct hsa-miR-618:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-32 8.42E-29 4.05E-31 3.70E-30 86 1594 "SFTA3,MAP1B,SMIM15,IL17D,ATP6V1G3,ANKRD34B,EP400,BLZF1,ARL1,NOP14,STXBP6,ATP7B,CACNA1E,MPZL1,FCHO2,NFXL1,SLC5A8,FAM177A1,PCSK1,RGSL1,PDE4D,CFL2,CHD1,WDFY2,CKMT2,ATAD2B,AKAP6,RCHY1,CLOCK,PREPL,SNCAIP,C12orf65,UBXN2A,FCRL5,NOS1AP,SREK1,TBC1D4,CEP120,GNPDA2,SLC35F6,WDR1,NR1H4,RAN,ARGLU1,TMEM161B,ZNF329,SPATA9,KLHL12,CWC27,DLEU1,ELOVL7,SH3YL1,TRAPPC13,FCAR,FLT1,SGCG,UFM1,THADA,YPEL5,LIMCH1,MEGF10,GABRA2,MYT1L,FAM114A1,NMNAT2,ERAP1,NFASC,PCDH17,PPARGC1A,GJA3,GJB2,ADAM17,ADGRL3,ARHGEF28,TNR,ADAMTS19,ARHGAP30,LTB4R2,DCP2,IL6ST,ANKS1B,ZBTB41,LHX9,CHPT1,DNAH10,SPRYD7" MicroRNA hsa-miR-605:mirSVR_lowEffct hsa-miR-605:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-32 8.73E-29 4.16E-31 3.81E-30 95 1945 "RALGAPA1,COG6,NYNRIN,FBRSL1,APBB2,WDR19,ARHGAP5,ATP12A,MYBPC1,BCL2L2,NFATC4,LINC02347,PNP,CACNA1E,MPZL1,NFXL1,PCCA,PCDH9,ZMYM5,CDK17,CENPC,CFL2,PFKFB2,PGGT1B,AKAP6,THTPA,VCAN,LRRTM2,FAM169A,DNM3,COG3,OCIAD1,TINF2,RABGAP1L,TSEN15,RNF219,DNMT3A,B3GLCT,SMC6,AASDH,LAP3,CRYL1,TXNDC15,LATS2,TRIM28,ARSK,FAM81B,PCGF3,ELOVL7,TRAPPC13,FCGR2B,UTP15,POLK,FOXO1,FLT1,HSD17B7,RASA3,G2E3,SLC30A6,STPG4,THADA,PKD2L2,NR5A2,LIMCH1,ZNF274,DRC1,PPARGC1A,GJA3,DHRS4,ADGRA3,ARHGEF28,COX18,TEP1,NT5C1B,CRB1,SLC7A8,AP4S1,ATP6V0A2,TXK,ZNF550,STARD4,CENPH,ZNF470,IL6ST,CCDC169,ZMYM2,ZBTB41,LHX9,ZBED3-AS1,LMLN,DIAPH3,AXDND1,LIG4,LOX,ZNF304" MicroRNA hsa-miR-1255a:mirSVR_lowEffct hsa-miR-1255a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-32 8.74E-29 4.16E-31 3.81E-30 89 1709 "MAP1B,MATN3,DHX37,PPFIA4,APAF1,BLZF1,WDR19,FAM193A,AACS,NCOA1,ATP2B4,CD84,ARHGEF7,LINC02347,CACNA1E,TAF1B,CD1D,UHMK1,PCDH9,PDGFRA,PFKFB2,CHIT1,ZNF595,POLN,PTPRVP,C1orf116,THTPA,LYSMD3,NGDN,DNM3,CMTM5,SPATA18,PIGG,CEP350,OCIAD1,PARPBP,C14orf119,RB1,OGFOD2,POLR1D,PACRGL,EFNA5,RNF4,MBNL2,FCAMR,STX2,FAM172A,ADGRV1,GMPR2,TOMM40L,SPON2,TNFRSF19,FTLP10,ZCCHC8,RUBCNL,SLC34A2,NBEA,UFM1,SLC12A2,SLC15A4,C1orf112,SLC22A4,UGGT2,MEGF10,PDS5B,JPH4,NAAA,LRCH1,LILRB1,PPARGC1A,TBC1D1,ANO4,C5orf56,DOCK9,RNF212,FCRLA,CRB1,ZBTB49,TMPO,ZNF876P,NSD2,C12orf73,GALP,KIR2DS4,RNASE11,LAD1,LINC01913,SPRYD7,MICU2" MicroRNA hsa-miR-452*:mirSVR_highEffct hsa-miR-452*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-32 9.61E-29 4.56E-31 4.17E-30 79 1341 "SMIM15,MDM4,ATP6V1G3,WDR35,DDX55,NCOA1,STARD13,ARHGEF7,BTF3,CAST,LDB2,CD1E,SCARB1,NFXL1,ZNF664,PCDH9,ZMYM5,PDE4D,CHIT1,PGGT1B,MRPL57,SMIM14,PIK3C2B,ATAD2B,THAP6,CLOCK,MPHOSPH8,PRKD1,FCRL5,GNPDA2,NR1H4,EGLN3,FAM129A,RASA1,RB1,TMEM161B,NTN4,SETDB2,TXNDC15,ELF1,MARVELD2,BORA,DEPDC4,ARSK,PCGF3,ELOVL7,TMEM156,SUCO,FLT1,RUBCNL,FBXO11,SCYL2,IVNS1ABP,CGREF1,HSPH1,DRC1,NEDD1,GJA3,STRN,DHRS4,GOLGA3,ANO4,GPR12,TDG,HEXB,GPN1,TECRL,HSD17B4,JCHAIN,ZNF470,IL6ST,ZMYM2,FAM49A,NPHS2,ANKDD1B,NUAK2,AXDND1,LMNB1,CDK2AP1" MicroRNA hsa-miR-664*:mirSVR_highEffct hsa-miR-664*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.13E-32 1.13E-28 5.34E-31 4.89E-30 67 943 "ADD1,KIAA1211,MCFD2,APC,BLZF1,FAM193A,KCTD12,PROZ,CHAMP1,FCRLB,ZNF664,ZMYM5,RGSL1,CHD1,CCDC122,ZNF595,GPR180,MRPL57,AKAP6,LACC1,LRRTM2,UBXN2A,NOS1AP,CEP350,TBC1D4,PARPBP,PPP2R3C,GALNT14,ATG10,RASA1,ZNF419,SETDB2,GUSBP3,PACRGL,UGT2A3,GP6,POLK,SDC1,MROH9,FLT1,THADA,SLC22A5,DCAF11,GABRB1,KIF21B,NAAA,HSPH1,OXGR1,DRC1,LRCH1,ZNF544,INSM2,ANO4,LINC01551,TMPO,HEXB,UBE2K,HMGCR,GUF1,STARD4,JCHAIN,FAM151B,CHPT1,RNASE11,TTC41P,FAM71C,AXDND1" MicroRNA hsa-miR-513b:mirSVR_highEffct hsa-miR-513b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-32 1.18E-28 5.54E-31 5.07E-30 76 1240 "CCDC181,ATP4B,KCTD12,ARHGEF7,CCNB1,CD1E,ZMYM5,PDE4D,CENPC,SLC25A3,ATAD2B,ADGRF3,THAP6,CSNK1G3,PRKD1,SREK1,TINF2,WDR1,PARPBP,NR1H4,ARGLU1,ZNF419,POLR1D,EFNA5,RNF4,DHRS2,BORA,STX2,FAM172A,ARSK,ADGRV1,SH3YL1,USP44,GORAB,VEZT,MBIP,UFM1,IVNS1ABP,THADA,TADA1,MRPS14,SNRPF,MYT1L,GABRB1,ADCY10,PDS5B,KDM5B,JPH4,HSPH1,OXGR1,MRPS27,SRP72,DRC1,ZNF544,UGT2A1,ADGRL3,GPR18,EML4,COP1,CRB1,GTF3C2,BAZ1A,MAEL,NPL,HEXB,ADAMTS19,GPN1,PAPPA2,NSD2,TPTE2,ZMYM2,FAM49A,TTC41P,SPRYD7,LOX,MICU2" MicroRNA hsa-miR-136:mirSVR_highEffct hsa-miR-136:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.35E-32 1.25E-28 5.85E-31 5.35E-30 83 1491 "IL17D,ADD1,WDR35,FBRSL1,MSH2,NOVA1,CACNA1E,FCHO2,FCGR2C,PCCA,RGSL1,THAP6,HOMER1,STRN3,SNCAIP,VCAN,CEP135,DNM3,FCRL5,NOS1AP,PIGG,SACS,RABGAP1L,PARPBP,RABGGTA,GALNT14,EGLN3,TMEM161B,AASDH,RGS4,GRTP1,MBNL2,TRAPPC12,DRAM1,FAM81B,ETF1,PCBD2,FCGR3B,NDUFAF7,GORAB,SUCO,FLT1,FLT3,FBXO11,NUBPL,UFM1,IVNS1ABP,ARHGEF40,CCDC88A,SLC12A2,SLC15A4,CGREF1,C1orf112,SLC22A5,MEGF10,GABRA2,JPH4,NAAA,CMPK2,MIMT1,PPARGC1A,PSME4,ATP11A,ADAM17,ADGRL3,ANO4,TCF7,DOCK9,TDG,NCSTN,TEP1,TFDP1,HAL,NPL,HEXB,KLF12,GPN1,GUF1,DCP2,FCRL6,IL6ST,GALP,AXDND1" MicroRNA hsa-miR-3171:mirSVR_highEffct hsa-miR-3171:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-32 1.34E-28 6.25E-31 5.72E-30 74 1174 "RALGAPA1,NLN,ANKRD34B,RGS5,APC,MPZL1,RILPL1,RGSL1,PDGFRA,CFL2,ZNF595,NRXN1,GNPTAB,BRI3BP,VCAN,LRRTM2,FCRL5,ZNF586,IFT172,MATR3,PSME1,SREK1,DMXL1,SACS,G3BP2,PARPBP,PPP2R3C,EGLN3,RB1,AASDH,IPO4,DTD2,CLIP4,POLR1D,LATS2,EIF2B1,SPATA9,UGT2A3,BORA,FAM172A,UTP15,POLK,FLT1,FLT3,FBXO11,TADA1,ZNF605,NR5A2,LIMCH1,GABRB1,KIF21B,PDS5B,NEDD1,ZBTB37,METAP2,DOCK9,RNF212,COP1,TFDP1,AP4S1,TMPO,FZD10,HEXB,ZNF550,WDR36,SPTSSA,ZMYM2,PGAM5,LHX9,FAM151B,DIAPH3,EP400P1,RMST,AXDND1" MicroRNA hsa-miR-138-2*:mirSVR_highEffct hsa-miR-138-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-32 1.38E-28 6.38E-31 5.84E-30 81 1420 "SFTA3,MAP1B,MATN3,SLAMF6,ATP6V1G3,APAF1,NOP14,NCOA1,KCTD12,RAB29,TAF1B,CAST,AMDHD1,FCGR2C,CD1D,CD1E,CFL2,PGGT1B,TM9SF2,PIK3C2B,PKP1,THAP6,LYSMD3,CSNK1G3,VCAN,DNM3,ZFYVE16,SREK1,COG3,PTGS2,NUDT12,TSEN15,RNF219,NR1H4,TMEM161B,POLR1D,CWC27,STK32B,TRAPPC13,FNIP1,PIBF1,SUCO,FOXG1,VEZT,FBXO11,UFM1,THADA,TADA1,CCDC88A,SLC15A4,LIMCH1,MEGF10,RAPGEF6,KDM3B,GC,IKBIP,COMMD6,GJB2,SCFD1,METAP2,ADGRL3,C5orf56,RXFP2,VRK2,NSD2,FCRL6,IGF1,KCNT2,JCHAIN,ZNF470,C12orf73,IL6ST,CCDC169,ZMYM2,FAM151B,FIP1L1,LAD1,RMST,AXDND1,LIG4,LMNB1" MicroRNA hsa-miR-9:mirSVR_highEffct hsa-miR-9:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.60E-32 1.38E-28 6.38E-31 5.84E-30 80 1384 "MDM4,BIRC6,ACOX3,ANKRD34B,COG6,CUL4A,MSH2,BLZF1,ATP2B4,STARD13,KCTD12,LINC02347,DAOA,CHAMP1,UHMK1,FAM177A1,PDE4D,SLC25A3,ITGBL1,THAP6,POLE,POU2F1,CLOCK,VCAN,DNM3,FCRL5,FCRL2,MATR3,PTGS2,NUDT12,SACS,PARPBP,C14orf119,NR1H4,B3GLCT,AASDH,IPO4,GRTP1,MBNL2,MARVELD2,FCAMR,ARSK,FAM81B,MAEA,ARL6IP4,FGF9,RELL1,PIBF1,FOXG1,SELP,BRMS1L,ALKAL2,UFM1,IVNS1ABP,SLC8A1,TADA1,CCDC88A,SLC12A2,C1orf112,NR5A2,LIMCH1,NAAA,TMEM183A,IKBIP,PCDH17,COMMD6,ANO4,DOCK9,TGFBI,NPL,TXK,VRK2,SPTSSA,FAM151B,TDRD3,ZBED3-AS1,CHPT1,KCNN2,LINC01913,RMST" MicroRNA hsa-miR-19a:mirSVR_highEffct hsa-miR-19a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.71E-32 1.44E-28 6.62E-31 6.06E-30 86 1606 "MATN3,MDM4,ACOX3,KIAA1211,WDR35,APAF1,ATP1A2,ATP12A,CD84,DAOA,CAST,UHMK1,SNTG2,RGSL1,PDE4D,GLT1D1,CFL2,NRXN1,JAKMIP1,HOMER1,STRN3,GNPTAB,LYSMD3,CLOCK,NGDN,LRRTM2,DNM3,DCAF8,SNX17,COG3,CEP350,TBC1D4,SACS,G3BP2,WDR1,PARPBP,RASA1,AASDH,CLIP4,MEMO1,EIF2D,ELK3,KLHL12,MPHOSPH9,SAP18,STK32B,ABCA11P,CLIP1,F10,FCAR,TNFRSF19,SUCO,SDC1,FLT1,VEZT,NBEA,PAICS,IVNS1ABP,SLC8A1,CCDC88A,LIMCH1,MYT1L,FAM114A1,RBKS,MCCC2,LRCH1,KLHL20,NPFFR2,MAST4,INSM2,C5orf56,RAB2B,FZD10,ZNF721,NPL,ADAMTS19,UBE2K,TXK,SLAIN1,TENT2,KCNT2,ANKS1B,LMLN,FIP1L1,RMST,AXDND1" MicroRNA hsa-miR-199b-5p:mirSVR_lowEffct hsa-miR-199b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.48E-32 1.85E-28 8.45E-31 7.74E-30 92 1844 "MAP1B,TMEM132B,NLN,ANKRD34B,COG6,NYNRIN,TBC1D14,SEMA6A,MCFD2,CENPBD1P1,STARD13,BCL2L2,CD84,FCRL3,ARHGEF7,AP1G2,RAB29,NOVA1,MPZL1,PDE4D,PDGFRA,CHD1,WDFY2,CKMT2,ITGBL1,NCR1,HECTD1,AKAP6,POU2F1,LYSMD3,KIAA0040,PRKD1,FCRL5,DCAF8,LOC439933,COCH,TINF2,SUPT7L,SLC35F6,PPP2R3C,METTL11B,RB1,SLC9C2,CLIP4,EFNA5,GRTP1,SPATA9,MPHOSPH9,DHRS2,BORA,TBC1D19,ARSK,DLEU1,DNAJC27,TRAPPC13,IRF9,TOMM40L,TNFRSF19,SUCO,STAB2,FBXO11,MBIP,THADA,ZNF605,SLC12A2,PKD2L2,WDCP,C1orf112,UGGT2,MYO16,MEGF10,PDS5B,TMEM183A,ZNF274,ZBTB37,LPIN1,ADAM17,PPIP5K2,KMT5A,DOCK9,GZMB,TNR,ADAMTS19,SLAIN1,NSD2,YTHDC2,ZNF26,LMLN,DIAPH3,EP400P1,SPRYD7,LMNB1" MicroRNA hsa-miR-1243:mirSVR_lowEffct hsa-miR-1243:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.54E-32 1.88E-28 8.53E-31 7.81E-30 86 1612 "SEMA6A,HOMEZ,RGS5,UVSSA,APBB2,ARHGAP5,SLC4A4,ARHGEF7,NOVA1,CDKL2,TAF1B,LDB2,PAH,PCK2,RGSL1,PDGFRA,GLT1D1,PDE6B,PFKFB2,CCDC122,WDFY2,TM9SF2,CLOCK,KIAA0040,FCRL5,ZFYVE16,DHX9,CEP350,COCH,CEP120,OCIAD1,GNPDA2,SUPT7L,C14orf119,ZNF329,DTD2,MEMO1,RNF4,MBNL2,TRAPPC12,SNORA53,KIRREL1,DHRS2,FCAR,FGFR3,POLK,SUCO,FLT1,STAB2,SUPT20H,ZCCHC8,MBIP,ARHGEF40,ZNF605,MEGF10,GABRB1,PDS5B,RAPGEF6,GJB6,MRPS27,KDM3B,MCCC2,ANKLE2,LRCH1,METAP2,ADGRA3,ANO4,TCF7,ARHGEF28,DOCK9,XPO4,COX18,FCRLA,GRSF1,UBE2K,TXK,WDR36,ZNF10,C12orf73,ZBED3-AS1,CAB39L,TTC41P,LINC01913,AXDND1,LIG4,IFT88" MicroRNA hsa-miR-20b:mirSVR_highEffct hsa-miR-20b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.54E-32 1.88E-28 8.53E-31 7.81E-30 86 1612 "MDM4,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,ARHGEF7,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,SNTG2,FAM177A1,PDE4D,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,NUDT12,CEP120,SACS,RABGAP1L,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,SNRPF,MYT1L,NAAA,ERAP1,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPARGC1A,BRD8,ARHGEF28,AP4S1,RIMBP2,NPL,KLF12,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,CDK2AP1,IFT88" MicroRNA hsa-miR-26b*:mirSVR_highEffct hsa-miR-26b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.82E-32 2.03E-28 9.16E-31 8.39E-30 79 1356 "MDM4,SLAMF6,COG6,EP400,CDKL4,ARHGAP5,FAM193A,NCOA1,SLC4A4,KCTD12,BCL2L2,BTF3,NOVA1,CD1D,PCCA,PCDH9,RGSL1,CENPC,WDFY2,ITGBL1,THAP6,GNPTAB,HEATR5A,SNCAIP,C12orf65,CEP135,FCRL5,SPATA18,COG3,FBXL5,TBC1D4,RASA1,NTN4,PACRGL,MARVELD2,FCAMR,CWC27,DLEU1,ADGRV1,F7,NDUFAF7,RELL1,PIBF1,SUCO,VEZT,NUBPL,IVNS1ABP,THADA,YPEL5,CHFR,NMNAT2,NAAA,CD244,NPAS3,DRC1,NPFFR2,PPARGC1A,STRN,LINC02393,C5orf56,COP1,TDG,NCSTN,TEP1,GTF3C2,MAEL,NPL,TPO,TECRL,DCP2,YTHDC2,ZNF470,SPTSSA,LHX9,FIP1L1,LCP1,RMST,SPRYD7,LOX" MicroRNA hsa-miR-376a:mirSVR_lowEffct hsa-miR-376a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.87E-32 2.06E-28 9.19E-31 8.42E-30 86 1614 "SFTA3,MAP1B,BIRC6,NLN,PITPNM2,WDR19,ARHGAP5,ARL1,ASTN1,CENPBD1P1,SLC4A4,KCTD12,CACNA1E,MPZL1,PAH,PCCA,DCLK1,XPR1,PIK3C2B,BOD1L1,HECTD1,STRN3,MPC2,COPA,EPGN,PREPL,CMTM5,FCRL2,DCAF8,LOC439933,NUDT12,PARPBP,RNF219,RASA1,RGS12,LRPPRC,RNASEL,GRTP1,UGT2A3,ELF1,TCTN2,ETF1,F7,USP44,FCGR2B,FNIP1,PIBF1,SUCO,FOXG1,FLT1,FLT3,HSD17B7,SFSWAP,BRMS1L,UFM1,SLC30A6,C1orf112,ACIN1,UGGT2,MEGF10,TMEM183A,IQGAP2,ATP8A2,NEDD1,PCDH17,PPARGC1A,GJA3,INSM2,SCFD1,GPR12,C1QTNF9B,TGFBI,AP4S1,GTF3C2,BAZ1A,MAEL,NPL,GPN1,SELENOI,C12orf73,IL6ST,CHPT1,AMTN,LAD1,RMST,AXDND1" MicroRNA hsa-miR-4295:mirSVR_lowEffct hsa-miR-4295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.87E-32 2.06E-28 9.19E-31 8.42E-30 86 1614 "MAP1B,MCC,ADD1,NLN,PITPNM2,ZNF784,WDR19,ASCL1,CENPBD1P1,ATP1A2,MYH6,NFATC4,AP1G2,LINC02347,NOVA1,RILPL1,UHMK1,PDE4D,CEBPE,CHD1,ITGBL1,HECTD1,STRN3,TAPT1,ITSN2,LRRTM2,FAM169A,ZNF586,SNX17,COG3,KLHL3,G3BP2,WDR1,PARPBP,PPP2R3C,RNF219,EGLN3,FAM129A,CLIP4,LRPPRC,RNASEL,EFNA5,ELF1,ZNF671,FNIP1,FOXG1,HSD17B7,NUBPL,SLC12A2,KIF21B,PDS5B,FAM114A1,TMEM183A,ZNF274,IQGAP2,GJB6,RBKS,NEDD1,COMMD6,PPARGC1A,ATP11A,ADGRA3,GPR12,ARHGEF28,DOCK9,TGM1,LINC01551,RIMBP2,ATP6V0A2,NPL,TPO,HSP90B1,UBE2K,RXFP2,NSD2,IGF1,ZMYM2,ZBTB41,LHX9,FAM151B,KCNN2,FIP1L1,KIT,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-4262:mirSVR_highEffct hsa-miR-4262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.36E-32 2.32E-28 1.03E-30 9.43E-30 91 1810 "MAP1B,MATN3,BIRC6,NLN,DDX55,ARL1,SLC4A4,ZNF542P,MYBPC1,NOVA1,CDKL2,CAST,CCNB1,CD1E,SLC5A8,ZNF664,PCSK1,PDGFRA,CENPC,CFL2,RCBTB2,PFKFB2,NRXN1,HOMER1,AKAP6,TAPT1,VCAN,CEP135,ZNF586,ZFYVE16,SPATA18,CEP350,NUDT12,TBC1D4,CEP120,OCIAD1,G3BP2,PPP2R3C,RAN,RB1,ZNF329,SMC6,ZNF419,TXNDC15,MBNL2,FCAMR,EFS,ETF1,CLIP1,FNIP1,SUCO,FLT1,SUPT20H,FBXO11,G2E3,UFM1,TADA1,CCDC88A,MRPS14,DCAF11,GABRA2,PDS5B,NAAA,GJB6,HSPH1,OXGR1,NPAS3,CMPK2,ZNF544,TBC1D1,PPIP5K2,METAP2,ADGRL3,ANO4,TGFBI,RASSF6,HSP90B1,TXK,GUF1,ZNF550,NLRP8,STARD4,IL25,YTHDC2,TADA2B,CCDC169,ZNF140,ZMYM2,LHX9,LIG4,IFT88" MicroRNA hsa-miR-875-5p:mirSVR_lowEffct hsa-miR-875-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-32 2.33E-28 1.03E-30 9.46E-30 76 1253 "HOMEZ,CUL4A,FBRSL1,APC,ARHGAP5,ARL1,NCOA1,KCTD12,ARHGEF7,CACNA1E,MPZL1,UHMK1,SLC5A8,PCDH9,FAM177A1,PCSK1,RGSL1,PDGFRA,ZNF595,WDFY2,CFAP54,SMIM14,ATAD2B,THAP6,CLOCK,PREPL,VCAN,DDX59,CEP350,RABGAP1L,PARPBP,DNMT3A,FAM228A,RNASEL,TXNDC15,DCUN1D2,UGT2A3,TRAPPC13,FOXG1,PEAR1,ZCCHC8,BRMS1L,GFM2,ZNF605,C1orf112,ZNF667,TMEM183A,ERAP1,MRPS27,IKBIP,MIMT1,LPIN1,GJA3,GJB2,MAST4,ANO4,EML4,XPO4,MSH6,GTF2H3,RIMBP2,MAEL,NPL,HPCAL1,PAPPA2,HTR2A,JCHAIN,IL6ST,CCDC169,SPTSSA,ANKS1B,FAM151B,ZBED3-AS1,LCP1,AXDND1,ZNF304" MicroRNA hsa-miR-19b-2*:mirSVR_highEffct hsa-miR-19b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-32 2.43E-28 1.07E-30 9.81E-30 78 1324 "KIAA1211,WDR35,SEMA6A,SNX24,CDKL4,BLZF1,ARHGEF7,CAST,FCGR2C,SNTG2,ZMYM5,PDE4D,CFL2,ITGBL1,NRXN1,LTB4R,THAP6,RCHY1,CLOCK,ITSN2,PRKD1,IFT172,DMXL1,NUDT12,PTPRC,DNMT3A,RB1,EIF2D,RNASEL,EIF2B1,CWC27,ABCA11P,TOMM40L,FNIP1,SUCO,SDC1,FLT1,FMO1,BRMS1L,IVNS1ABP,PKD2L2,UGGT2,LIMCH1,MYO16,MEGF10,ATP8A2,KDM3B,GC,MCCC2,IKBIP,KLHL20,COMMD6,PSME4,TMED2,PPIP5K2,MTUS2,ADGRL3,COP1,TDG,CRB1,TMPO,ZNF721,TXK,TENT2,NSD2,KCNT2,JCHAIN,PLB1,ANKS1B,ZMYM2,LHX9,FAM151B,ZBED3-AS1,TMEM178A,ANKDD1B,LAD1,LCP1,LOX" MicroRNA hsa-miR-92a:mirSVR_lowEffct hsa-miR-92a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-32 2.91E-28 1.28E-30 1.17E-29 87 1660 "SFTA3,CUL4A,APBB2,DDX55,BLZF1,ARL1,AACS,NCOA1,ASTN1,SLC4A4,ATP7B,NRL,CAMK4,RILPL1,SLC5A8,PCDH9,FAM177A1,XPR1,CDK7,PDE4D,PDGFRA,SLC25A3,SMIM14,PITX1,HOMER1,EPGN,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SREK1,LOC439933,CEP350,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DTD2,CLIP4,POLR1D,LGR6,TBC1D19,GP6,FAM172A,DEPDC4,ARSK,STK32B,DNAJC27,FCAR,RELL1,FOXG1,RASA3,FBXO11,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,CMPK2,MCCC2,ERBIN,IKBIP,STRN,ADAM17,PPIP5K2,EML4,KMT5C,RNF17,LINC01551,ADAMTS19,TRPC4,HMGCR,TMEM174,VRK2,YTHDC2,IRF1,TMEM178A,DIAPH3,LAD1" MicroRNA hsa-miR-323b-3p:mirSVR_lowEffct hsa-miR-323b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.70E-32 3.03E-28 1.32E-30 1.21E-29 83 1510 "RALGAPA1,IL17D,BIRC6,HOMEZ,EP400,CDKL4,BLZF1,ARL1,STXBP6,CD84,NFKBIA,CAST,AMDHD1,FCHO2,ZMYM5,PDE4D,CENPC,PFKFB2,DHRS1,ZNF595,TM9SF2,SNX6,NUP37,THAP6,HOMER1,STRN3,TAPT1,POU2F1,SNCAIP,IL20,DNM3,NOS1AP,SPATA18,SREK1,COG3,COCH,SACS,DNMT3A,AASDH,RGS12,CLIP4,MEMO1,SETDB2,GUSBP3,LRPPRC,RNASEL,DHRS2,SH3YL1,MROH9,FLT1,RUBCNL,BRMS1L,PAICS,UFM1,GFM2,IVNS1ABP,CCDC88A,SF3B6,FSHR,UGGT2,MYO16,GABRA2,MYT1L,NAAA,ZNF274,ERAP1,ATP8A2,RBKS,KLHL20,CFHR4,TCF7,ADAMTS19,TECRL,SLAIN1,TENT2,NSD2,IL6ST,FAM151B,CHPT1,LIG4,PABPN1,LTA4H,MICU2" MicroRNA hsa-miR-576-3p:mirSVR_lowEffct hsa-miR-576-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.26E-32 3.33E-28 1.45E-30 1.33E-29 95 1979 "SMIM15,SLAMF6,MSH2,ARHGAP5,NOP14,FAM193A,CENPBD1P1,SLC4A4,KCTD12,MYH7,SLC5A6,PNP,CBLN3,CAST,UHMK1,CDK7,CENPC,PMCH,C1orf116,AKAP6,FAM163A,TAPT1,RCHY1,FAM53A,SYCP3,HEATR5A,LYSMD3,BRI3BP,CSNK1G3,ITSN2,FAM169A,DNM3,EIF2AK2,COG3,PTGS2,FBXL5,LOC439933,OCIAD1,PTPRH,TINF2,SACS,RABGAP1L,RAN,FAM129A,ATG10,RNF31,SMC6,RGS12,EIF2B1,KLHL12,MPHOSPH9,STX2,DRAM1,N4BP2L2,TNFRSF19,RELL1,POLK,FMO1,TM9SF1,FBXO11,PLEKHA6,STPG4,SCYL2,SLC8A1,CGREF1,FAM114A1,NMNAT2,ZNF274,GJB2,LINC02393,LILRB4,ANO4,GPR12,TCF7,ARHGEF28,XPO4,TEP1,GRSF1,AP4S1,TMPO,MAEL,UBE2K,HMGCR,SLAIN1,WDR36,STARD4,YTHDC2,ITLN2,ZNF10,FAM49A,ANKDD1B,RMST,NUAK2,LOX,SPATA13" MicroRNA hsa-miR-141:mirSVR_highEffct hsa-miR-141:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.88E-32 3.66E-28 1.58E-30 1.45E-29 86 1627 "SMIM15,MDM4,ADD1,UVSSA,BLZF1,STXBP6,ASTN1,KCTD12,BTF3,TAF1B,CAST,CD1E,PCDH9,ZMYM5,XPR1,CDK7,CDK17,CFL2,CHD1,WDFY2,SLC25A3,COLEC11,ATAD2B,EPN1,HECTD1,THTPA,HEATR5A,LYSMD3,PREPL,LACC1,CSNK1G3,VCAN,DNM3,PRKD1,DDX59,SREK1,COG3,NUDT12,CEP120,WDR1,PARPBP,RB1,CRYL1,LATS2,STX2,FAM172A,CWC27,STK32B,PCGF3,CLIP1,FNIP1,SUCO,FLT1,SUPT20H,VEZT,ALKAL2,UFM1,TADA1,CCDC88A,YPEL5,LIMCH1,MEGF10,GABRA2,MYT1L,PDS5B,NPAS3,LRCH1,PPARGC1A,STRN,ZNF544,GOLGA3,ADGRL3,GPR12,YIPF7,FCRLA,LINC01551,HEXB,TENT2,VRK2,HTR2A,KCNT2,ANKS1B,CHPT1,KIT,PABPN1,LOX" MicroRNA hsa-miR-548m:mirSVR_highEffct hsa-miR-548m:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.93E-32 4.75E-28 2.04E-30 1.87E-29 90 1788 "ABL2,MAP1B,MATN3,MDM4,COG6,WDR35,APAF1,ATP1A2,ZNF542P,NFATC4,BTF3,NOVA1,PCDH9,RGSL1,PDGFRA,VIT,ITGBL1,SNX6,ATAD2B,BOD1L1,AKAP6,LACC1,EIF2AK2,GLT8D2,DCAF8,MATR3,BIVM,SREK1,NUDT12,C14orf119,RNF219,FAM129A,B3GLCT,CLIP4,PACRGL,RNASEL,LATS2,FAM172A,DLEU1,CLIP1,FCGR2B,GORAB,TNFRSF19,RELL1,PIBF1,SUCO,SUPT20H,VEZT,RUBCNL,SLC30A6,CCDC88A,SLC12A2,N4BP2,SLC22A5,FSHR,YPEL5,LIMCH1,GABRB1,PDS5B,KDM5B,CD244,ATP8A2,NPAS3,CMPK2,NFASC,SRP72,IKBIP,KLHL20,LPIN1,GJA3,ADGRL3,ANO4,CRB1,ACTR6,HMGCR,GUF1,HSD17B4,ZNF876P,NLRP8,KCNT2,ANKS1B,ZBTB41,FAM151B,TDRD3,FAM49A,CHPT1,KIF2A,RMST,LMNB1,LOX" MicroRNA hsa-miR-1231:mirSVR_lowEffct hsa-miR-1231:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.95E-32 4.76E-28 2.04E-30 1.87E-29 86 1633 "MAP1B,LRRC43,MDM4,ADD1,KIAA1211,SNX24,CDKL4,MSH2,BLZF1,ARL1,CENPBD1P1,FGFRL1,ARHGEF7,ODC1,CHAMP1,CD1E,SNTG2,RFLNA,PDE4D,ITGBL1,PTPRVP,AKAP6,TAPT1,FAM53A,TOGARAM2,LYSMD3,SNCAIP,VCAN,DNM3,FCRL5,COG3,FBXL5,PARPBP,ATG10,RNF31,RASA1,ZNF329,OGFOD2,RGS12,MEMO1,TXNDC15,ZNF256,MARVELD2,DHRS2,CWC27,DLEU1,ABCA11P,CLIP1,FCAR,TOMM40L,GORAB,POLK,SUCO,STAB2,ALKAL2,ZNF446,STPG4,SLC8A1,CCDC88A,UGGT2,SNRPF,FAM114A1,CD244,RBKS,ANKLE2,ERBIN,COMMD6,MAST4,MTUS2,LILRB4,ANO4,GPR12,EML4,RNF17,ZBTB49,MSH6,LINC01551,IL25,ZMYM2,LHX9,KCNJ9,ANKDD1B,KIR2DS4,TTC41P,SPRYD7,AXDND1" MicroRNA hsa-miR-377:mirSVR_highEffct hsa-miR-377:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-31 5.42E-28 2.31E-30 2.12E-29 86 1636 "ULK1,CUL4A,ARHGAP5,NOP14,NCOA1,ASTN1,CD84,SLC5A6,CAST,FCHO2,PCCA,PCSK1,PDGFRA,CFL2,MRPL57,SMIM14,AKAP6,TAPT1,GNPTAB,HEATR5A,LYSMD3,LACC1,CSNK1G3,ITSN2,CEP135,PRKD1,FCRL2,COG3,KLHL3,NUDT12,PTPRC,G3BP2,C14orf119,DNMT3A,RASA1,RB1,AASDH,ZNF419,SETDB2,LRPPRC,LATS2,MARVELD2,DRAM1,ABCA11P,NDUFAF7,N4BP2L2,FMO1,TM9SF1,NBEA,PLEKHA6,THADA,SLC12A2,C1orf112,PDS5B,NAAA,IQGAP2,ATP8A2,NPAS3,KDM3B,PSME4,TBC1D1,TMED2,ADGRL3,ARHGEF28,GRSF1,ACTR6,TMPO,ZNF721,HMGCR,GUF1,ZNF550,HTR2A,NSD2,JCHAIN,ZMYM2,IRF1,LHX9,FAM49A,CAB39L,KIF2A,RNASE11,NUAK2,AXDND1,LIG4,IFT88,MICU2" MicroRNA hsa-miR-4324:mirSVR_lowEffct hsa-miR-4324:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-31 5.43E-28 2.31E-30 2.12E-29 89 1752 "MAP1B,ADD1,ATP6V1G3,WDR35,HOMEZ,MSH2,AACS,STARD13,BCL2L2,BTF3,LINC02347,DAOA,FCHO2,PCCA,PCDH9,PCK2,GLT1D1,PDE6B,ADGRF3,PTPRVP,THAP6,C1orf116,TAPT1,TOGARAM2,POU2F1,CSNK1G3,MPHOSPH8,NOS1AP,SPATA18,PSME1,PIGG,PTGS2,DMXL1,CEP350,F11R,DHFR,LINC01257,TSEN15,NR1H4,RABGGTA,DNMT3A,GALNT14,B3GLCT,RGS12,POLR1D,RNF4,MBNL2,STX2,CWC27,ABCA11P,ELOVL7,TACC3,FLT3,SUPT20H,RASA3,VEZT,GOLGA2P5,FBXO11,NBEA,BRMS1L,ALKAL2,IVNS1ABP,THADA,ZNF667,TMEM183A,NFASC,DRC1,LPIN1,TBC1D1,CNTN2,ADGRL3,GPR12,TCF7,KHNYN,TDG,BAZ1A,ADAMTS19,ARHGAP30,HMGCR,C12orf73,ZMYM2,CHPT1,LMLN,TTC41P,LCP1,LINC00442,NUAK2,TTC7A,ZNF304" MicroRNA hsa-miR-155:mirSVR_highEffct hsa-miR-155:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.04E-31 5.50E-28 2.33E-30 2.14E-29 81 1449 "TBC1D14,APAF1,BLZF1,NOVA1,CDKL2,CAST,SLC5A8,PCCA,PCDH9,ZMYM5,FAM177A1,WDR66,PDE4D,RCBTB2,NRXN1,ATAD2B,STRN3,TAPT1,LYSMD3,BRI3BP,IL20,LRRTM2,PRKD1,PTGS2,NUDT12,COCH,TBC1D4,G3BP2,SLC35F6,NR1H4,FAM129A,B3GLCT,AASDH,CRYL1,NTN4,MBNL2,DCUN1D2,ELF1,MPHOSPH9,MARVELD2,TBC1D19,DRAM1,CWC27,ABCA11P,TRAPPC13,FGF9,FBXO11,G2E3,UFM1,TADA1,SLC12A2,C1orf112,MRPS14,LIMCH1,MEGF10,KIF21B,KDM5B,MRPS27,CMPK2,NEDD1,LRCH1,IKBIP,NPFFR2,LPIN1,LINC02393,METAP2,ADGRL3,DOCK9,YIPF7,GRSF1,ZNF721,HAL,GUF1,YTHDC2,JCHAIN,TADA2B,SPTSSA,ZMYM2,LHX9,ZBED3-AS1,LIG4" MicroRNA hsa-miR-26a-1*:mirSVR_highEffct hsa-miR-26a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-31 5.71E-28 2.41E-30 2.21E-29 79 1377 "MDM4,ANKRD34B,SNX24,SLC4A4,RAB29,CACNA1E,CHAMP1,CD1E,FCRLB,PCCA,FAM177A1,PDE4D,PFKFB2,WDFY2,SMIM14,ADGRF3,C1orf116,COPA,GNPTAB,SYCP3,LYSMD3,FCRL5,DCAF8,PIGG,PTGS2,DMXL1,FBXL5,CEP350,NUDT12,TBC1D4,PARPBP,FAM129A,TMEM161B,IPO4,DTD2,RGS4,RGS12,MEMO1,POLR1D,PACRGL,EFNA5,ELF1,CWC27,ADGRV1,PCBD2,FCGR3A,FBXO11,G2E3,BRMS1L,NUBPL,SLC8A1,THADA,NR5A2,ZNF667,CYP1B1-AS1,MYT1L,EAPP,ERAP1,OXGR1,RBKS,COMMD6,STRN,GJB2,C5orf56,DOCK9,COX18,NT5C1B,HEXB,TMEM174,VRK2,PLB1,ANKS1B,FAM151B,AMTN,RNASE11,TTC41P,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-574-5p:mirSVR_lowEffct hsa-miR-574-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-31 6.15E-28 2.59E-30 2.37E-29 89 1755 "RALGAPA1,MAP1B,LRRC43,NLN,SLAMF6,COG6,NYNRIN,MIPEP,RGS5,MSH2,AACS,NCOA1,STARD13,CD84,ARHGEF7,AP1G2,LINC02347,ADGRD1,CBLN3,CDKL2,ODC1,FCGR2C,PCK2,PDE4D,CHD1,CCDC122,WDFY2,GPR180,ADGRF3,HOMER1,COPA,EPGN,LYSMD3,SNCAIP,KIAA0040,FCRL5,ZFYVE16,COG3,CEP350,PTPRC,G3BP2,OGFOD2,CLIP4,PACRGL,FAM172A,ADGRV1,GORAB,SUCO,FOXO1,FLT1,STAB2,NBEA,IVNS1ABP,ARHGEF40,ZNF605,PKD2L2,POTEM,CGREF1,SLC22A4,SLC22A5,DCAF11,CYP1B1-AS1,MYO16,KIF21B,NMNAT2,KDM3B,LILRB1,LPIN1,UTP20,ATP11A,GPR12,KMT5A,RNF212,TDG,TGFBI,RIMBP2,ADAMTS19,GPN1,RXFP2,HSD17B4,WDR36,STARD4,ZNF10,KIF2A,EP400P1,LETM1,NUAK2,AXDND1,MICU2" MicroRNA hsa-miR-17:mirSVR_highEffct hsa-miR-17:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.22E-31 6.49E-28 2.71E-30 2.48E-29 85 1602 "MDM4,BIRC6,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,ARHGEF7,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,SNTG2,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,NUDT12,CEP120,SACS,RABGAP1L,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,ERAP1,NPAS3,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPARGC1A,BRD8,ARHGEF28,RNF17,AP4S1,RIMBP2,NPL,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,CDK2AP1,IFT88" MicroRNA hsa-miR-106a:mirSVR_highEffct hsa-miR-106a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.22E-31 6.49E-28 2.71E-30 2.48E-29 85 1602 "MDM4,BIRC6,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,ARHGEF7,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,SNTG2,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,NUDT12,CEP120,SACS,RABGAP1L,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,ERAP1,NPAS3,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPARGC1A,BRD8,ARHGEF28,RNF17,AP4S1,RIMBP2,NPL,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,CDK2AP1,IFT88" MicroRNA hsa-miR-1197:mirSVR_lowEffct hsa-miR-1197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-31 7.28E-28 3.02E-30 2.77E-29 91 1838 "MDM4,NDRG2,ADD1,NLN,CUL4A,UVSSA,DDX55,FAM193A,SLC4A4,KCTD12,ATP7B,NFATC4,LINC02347,ADGRD1,NOVA1,TAF1B,CAST,CD1E,RFLNA,PCDH9,CFL2,CHIT1,CPNE6,TM9SF2,POLN,AKAP6,TAPT1,LYSMD3,PREPL,DNM3,FCRL5,ZNF586,IFT172,SNX17,COG3,CEP350,KLHL3,G3BP2,WDR1,PARPBP,RGS12,POLR1D,PACRGL,MBNL2,MARVELD2,DRAM1,STK32B,ABCA11P,F7,FCGR3A,FCGR3B,RELL1,PIBF1,FOXG1,ZNF605,SLC12A2,PKD2L2,N4BP2,WDCP,NR5A2,YPEL5,LIMCH1,DCAF11,GABRB1,KDM5B,NMNAT2,JPH4,NFASC,DRC1,PCDH17,BRD8,PSME4,METAP2,CNTN2,ARHGEF28,NCSTN,LINC01551,BAZ1A,ACTR6,HAL,ADAMTS19,VRK2,NSD2,ZNF10,ZNF470,IL6ST,IRF1,CAB39L,ZDHHC20,IFT88,PABPN1" MicroRNA hsa-miR-297:mirSVR_lowEffct hsa-miR-297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-31 7.41E-28 3.06E-30 2.81E-29 85 1605 "MCC,TMEM132B,ULK1,CUL4A,ARHGAP5,ARL1,FGFRL1,GAS2L3,MPZL1,RILPL1,FCHO2,SLC5A8,PDGFRA,PDE6B,TAPT1,GNPTAB,POU2F1,LYSMD3,CRHBP,DNM3,PRKD1,ZNF586,DCAF8,DMXL1,CEP350,F11R,LINC01257,TSEN15,ATG10,RASA1,AASDH,DTD2,RGS4,SETDB2,PACRGL,TXNDC15,MPHOSPH9,DHRS2,STX2,FAM172A,TOMM40L,FGFR3,RELL1,PIBF1,POLK,FOXO1,UFM1,THADA,SLC12A2,C1orf112,SLC22A4,CIDEB,PDS5B,FAM114A1,NAAA,TMEM183A,HSPH1,GC,PCDH17,GOLGA3,TCF7,ARHGEF28,DOCK9,COX18,TFDP1,TGM1,LINC01551,RASSF6,MAEL,ATP6V0A2,UBE2K,GUF1,DCP2,YTHDC2,ZNF10,ZFHX2,CCDC169,LHX9,ZBED3-AS1,EP400P1,DNAH10,LCP1,RMST,LMNB1,IFT88" MicroRNA hsa-miR-3201:mirSVR_lowEffct hsa-miR-3201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-31 8.79E-28 3.62E-30 3.31E-29 74 1209 "RALGAPA1,MATN3,EP400,MSH2,ASTN1,KCTD12,BCL2L2,CACNA1E,CBLN3,MPZL1,CD1D,SLC5A8,DCLK1,GLT1D1,CFL2,LINC01085,BOD1L1,AKAP6,STRN3,EPGN,SNCAIP,LRRTM2,EIF2AK2,GLT8D2,BIVM,SPATA18,COG3,DMXL1,FBXL5,F11R,SMC6,GUSBP3,LATS2,MBNL2,ELF1,ELK3,BORA,STX2,DNAJC27,GMPR2,FCAR,N4BP2L2,ZCCHC8,FBXO11,G2E3,NBEA,CCDC88A,ACIN1,UGGT2,GABRA2,MYT1L,NAAA,NFASC,MCCC2,IKBIP,SULT1E1,STRN,ZNF544,CNTN2,ANO4,STON1,KHNYN,NCSTN,CRB1,GTF2H3,NPL,HEXB,TECRL,ZNF10,PLB1,ANKS1B,FIP1L1,LIG4,LMNB1" MicroRNA hsa-miR-383:mirSVR_lowEffct hsa-miR-383:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-31 9.71E-28 3.98E-30 3.65E-29 89 1766 "RALGAPA1,ADD1,SLAMF6,COG6,BLZF1,NCOA1,SLC4A4,KCTD12,ARHGEF7,BTF3,RAB29,ADGRD1,PNP,RILPL1,CHAMP1,DCLK1,FAM177A1,CDK7,PDE4D,CENPC,CFL2,VIT,ADGRF3,PTPRVP,FAM163A,DNM3,NOS1AP,COG3,OCIAD1,SACS,GNPDA2,RNF219,NR1H4,FAM129A,B3GLCT,ARGLU1,TMEM161B,DTD2,RGS12,TMEM33,MEMO1,POLR1D,LATS2,SNORA53,KIRREL1,ELF1,DHRS2,PCGF3,TMEM129,PIBF1,SUCO,SDC1,FOXO1,G2E3,NBEA,CCDC92,PLEKHA6,CCDC88A,ZNF605,SLC12A2,TMEM132D,MEGF10,MYT1L,CIDEB,KDM5B,ZNF274,IQGAP2,SULT1E1,PSME4,LINC02393,ACSL6,RNF212,FCRLA,NT5C1B,TFDP1,MSH6,ACTR6,TXK,GUF1,WDR36,ZNF26,ZNF470,IL6ST,PLB1,LMLN,FIP1L1,TTC7A,LIG4,IFT88" MicroRNA hsa-miR-606:mirSVR_lowEffct hsa-miR-606:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-31 1.13E-27 4.62E-30 4.23E-29 78 1355 "ADD1,ANKRD34B,NYNRIN,TBC1D14,HOMEZ,WDR19,ARHGAP5,STXBP6,SLC4A4,ZNF542P,ARHGEF7,NOVA1,MPZL1,NFXL1,DCLK1,XPR1,CDK17,CHD1,ZNF595,THAP6,PMCH,RCHY1,SNCAIP,IL20,ZFYVE16,FBXL5,F11R,RASA1,SMC6,REST,RGS12,RNASEL,EFNA5,TXNDC15,EIF2B1,SNORA53,KLHL12,ZNF671,DRAM1,SAP18,ETF1,PCGF3,IRF9,TNFRSF19,SUCO,SDC1,MROH9,SUPT20H,SGCG,FBXO11,NUBPL,PAICS,SLC30A6,SLC8A1,SLC12A2,NR5A2,YPEL5,GABRB1,NPAS3,PCDH17,COMMD6,STRN,GJB2,MAST4,PPIP5K2,STON1,DOCK9,FCRLA,RNF17,TFDP1,CRB1,GTF2H3,TXK,WDR36,TADA2B,IL6ST,ANKS1B,ANKDD1B" MicroRNA hsa-miR-335:mirSVR_highEffct hsa-miR-335:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.14E-31 1.14E-27 4.63E-30 4.24E-29 64 886 "NLN,ATP6V1G3,SNX24,APAF1,STXBP6,NCOA1,ADGRD1,PCDH9,DHRS1,NRXN1,SMIM14,C1orf116,AKAP6,TAPT1,CEP135,FCRL2,DCAF8,CEP350,OCIAD1,PTPRH,G3BP2,RASA1,RB1,ARGLU1,TMEM161B,RNASEL,MPHOSPH9,ETF1,PCGF3,GORAB,SUCO,SDC1,FOXO1,FLT1,SUPT20H,G2E3,PAICS,UFM1,SLC30A6,SLC12A2,SLC15A4,CHFR,PUS1,MYO16,GABRB1,RAPGEF6,SRP72,MCCC2,MIMT1,COP1,HEXB,ADAMTS19,GPN1,HMGCR,ZNF470,SPTSSA,ZMYM2,FAM151B,CHPT1,KIT,DNAH10,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-1826:mirSVR_highEffct hsa-miR-1826:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.15E-31 1.14E-27 4.63E-30 4.24E-29 74 1214 "MATN3,SMIM15,STARD13,ARHGEF7,NOVA1,FCHO2,LDB2,SLC5A8,ZMYM5,PDE4D,PDGFRA,LINC01085,SMIM14,UGT2B28,HOMER1,TOGARAM2,PM20D1,LACC1,LRRTM2,FAM169A,UBXN2A,FCRL5,EIF2AK2,DCAF8,ZFYVE16,SPATA18,SREK1,DMXL1,CEP350,OCIAD1,LINC01257,PARPBP,NR1H4,RASA1,SLC9C2,MEMO1,ZNF419,PACRGL,FCAMR,ETF1,DLEU1,UTP15,PIBF1,HSD17B7,SUPT20H,NBEA,NUBPL,THADA,N4BP2,SLC22A5,EFR3B,UGGT2,MEGF10,MYT1L,PDS5B,NAAA,NPAS3,DRC1,TBC1D1,ARHGEF28,BAZ1A,NPL,GUF1,SLAIN1,TENT2,STARD4,ANKS1B,ZMYM2,ZBED3-AS1,KIT,LAD1,LIG4,LTA4H,ZNF304" MicroRNA hsa-miR-220b:mirSVR_lowEffct hsa-miR-220b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.50E-31 1.33E-27 5.37E-30 4.91E-29 91 1853 "MDM4,ADORA1,KIAA1211,SLAMF6,NYNRIN,TBC1D14,SEMA6A,HOMEZ,RGS5,MSH2,BLZF1,WDR19,NOP14,STXBP6,SLC4A4,B4GALT3,CADM3,BCL2L2,CD1D,RFLNA,DCLK1,ZMYM5,PDGFRA,CENPC,GLT1D1,PFKFB2,CPNE6,CFAP54,SMIM14,COPA,NGDN,NCOR2,SNCAIP,CEP135,KIAA0040,NOS1AP,DCAF8,IFT172,SNX17,PIGG,PTGS2,KLHL3,PTPRH,PXMP2,C14orf119,RAN,POLR1D,PACRGL,UGT2A3,GP6,MAEA,ETF1,ABCA11P,ARL6IP4,TMEM156,FNIP1,STAB2,THADA,ARHGEF40,CCDC88A,ZNF667,GAK,UHRF1BP1L,ERBIN,LILRB1,TBC1D1,LINC02393,ADAM17,LILRB4,ACSL6,TCF7,KMT5C,TFDP1,SLC7A8,MSH6,LINC01551,BAZ1A,RAB2B,ZNF721,ADAMTS19,ZNF876P,TENT2,NLRP8,PLB1,ZMYM2,TDRD3,KCNJ9,DIAPH3,EP400P1,LAD1,AXDND1" MicroRNA hsa-miR-499-3p:mirSVR_highEffct hsa-miR-499-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-31 1.35E-27 5.41E-30 4.95E-29 75 1252 "SEMA6A,CUL4A,MSH2,WDR19,NCOA1,SLC4A4,NFKBIA,CDKL2,FCHO2,MORN2,PCK2,CDK17,PDGFRA,CENPC,PIWIL1,ZNF595,PIK3C2B,PKP1,UGT2B28,HOMER1,AKAP6,RCHY1,HEATR5A,SNCAIP,IL20,CSNK1G3,EIF2AK2,FCRL2,ZNF586,SREK1,PTGS2,CEP350,NUDT12,TINF2,RABGAP1L,EGLN3,RB1,CLIP4,RNASEL,MBNL2,UGT2A3,LGR6,BORA,DRAM1,EFS,CWC27,MAEA,ETF1,NDUFAF7,FNIP1,SUCO,FOXG1,UFM1,IVNS1ABP,MRPS14,ZNF667,MYT1L,KDM5B,CD244,TBC1D1,PPIP5K2,ADGRL3,ANO4,EML4,COP1,ZBTB49,LINC01551,ACTR6,RAB2B,HSP90B1,ZNF876P,JCHAIN,ZNF470,IL6ST,FAM49A" MicroRNA hsa-miR-374b*:mirSVR_lowEffct hsa-miR-374b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.81E-31 1.49E-27 5.97E-30 5.47E-29 90 1816 "MAP1B,MDM4,NDRG2,BIRC6,TMEM132B,KIAA1211,NLN,WDR35,APAF1,APBB2,WDR19,ARL1,STXBP6,CCDC181,ATP2B4,STARD13,BTF3,CCNA1,ODC1,FCHO2,ZNF664,PCK2,PDE4D,GPR180,LINC01085,LTB4R,POLN,THAP6,STRN3,GNPTAB,HEATR5A,LYSMD3,PREPL,DNM3,EIF2AK2,NOS1AP,FCRL2,MATR3,BIVM,COG3,SACS,SUPT7L,DTD2,MEMO1,LRPPRC,PACRGL,MBNL2,DEPDC4,DRAM1,CWC27,ADGRV1,FCAR,TNFRSF19,FLT3,HSD17B7,GOLGA2P5,ZCCHC8,NUBPL,SLC30A6,IVNS1ABP,PKD2L2,C1orf112,SLC22A5,YPEL5,CHFR,EFR3B,UGGT2,PDS5B,NAAA,IQGAP2,RBKS,IKBIP,NMU,AURKC,STRN,MAST4,MTUS2,XPO4,RNF17,NT5C1B,CRB1,RAB2B,TMPO,HPCAL1,ZNF26,SPTSSA,ANKS1B,ZMYM2,ZBTB41,LMNB1" MicroRNA hsa-miR-92b:mirSVR_lowEffct hsa-miR-92b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-31 1.63E-27 6.49E-30 5.94E-29 85 1623 "SFTA3,CUL4A,APBB2,DDX55,BLZF1,ARL1,AACS,NCOA1,ASTN1,ATP1A2,SLC4A4,ATP7B,NRL,CAMK4,SLC5A8,PCDH9,FAM177A1,XPR1,CDK7,PDE4D,PDGFRA,SLC25A3,SMIM14,PITX1,HOMER1,EPGN,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SPATA18,SREK1,LOC439933,CEP350,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DTD2,CLIP4,POLR1D,TBC1D19,GP6,FAM172A,DEPDC4,ARSK,STK32B,DNAJC27,FCAR,FOXG1,RASA3,FBXO11,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,CMPK2,ERBIN,IKBIP,STRN,ADAM17,PPIP5K2,EML4,KMT5C,RNF17,LINC01551,ADAMTS19,TRPC4,HMGCR,TMEM174,VRK2,YTHDC2,IRF1,TMEM178A,DIAPH3,LAD1" MicroRNA hsa-miR-143*:mirSVR_lowEffct hsa-miR-143*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.52E-31 1.87E-27 7.42E-30 6.80E-29 84 1588 "KIAA1211,APBB2,ARL1,AACS,ASTN1,CENPBD1P1,CCNB1IP1,NLRP4,FGFRL1,ARHGEF7,CAD,TAF1B,SNTG2,PCDH9,PDE4D,ZNF595,MRPL57,HECTD1,HEATR5A,C12orf65,UBXN2A,MATR3,DGKQ,NUDT12,COCH,G3BP2,LINC01257,PPP2R3C,RNF219,RNF31,RASA1,ZNF329,OGFOD2,AASDH,RGS12,NTN4,LRPPRC,TBC1D19,STX2,GP6,EFS,STK32B,DLEU1,ABCA11P,PCGF3,TRAPPC13,FCAR,FCGR2B,UTP15,NDUFAF7,PIBF1,SUCO,SDC1,FLT1,FTLP10,TM9SF1,NUBPL,NLRP2,STPG4,ARHGEF40,MYO16,NMNAT2,NAAA,CMPK2,NFASC,LPIN1,ADGRL3,TCF7,TDG,COX18,FCRLA,AP4S1,BAZ1A,TMPO,HAL,GUF1,SLAIN1,HSD17B4,ZFHX2,ZMYM2,KIT,EP400P1,LINC00442,LMNB1" MicroRNA hsa-miR-519d:mirSVR_highEffct hsa-miR-519d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.81E-31 2.03E-27 8.01E-30 7.33E-29 80 1440 "MDM4,BIRC6,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,SPATA18,PIGG,FBXL5,CEP120,SACS,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,GMPR2,USP44,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,ERAP1,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,PPARGC1A,ARHGEF28,AP4S1,RIMBP2,NPL,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,IFT88" MicroRNA hsa-miR-19b-1*:mirSVR_highEffct hsa-miR-19b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.36E-31 2.32E-27 9.12E-30 8.35E-29 76 1298 "KIAA1211,WDR35,SEMA6A,SNX24,CDKL4,BLZF1,CAST,FCGR2C,ZMYM5,PDE4D,CFL2,ITGBL1,NRXN1,LTB4R,THAP6,RCHY1,CLOCK,CSNK1G3,ITSN2,PRKD1,IFT172,DMXL1,NUDT12,PTPRC,DNMT3A,RB1,EIF2D,RNASEL,EIF2B1,STX2,CWC27,ABCA11P,TOMM40L,FNIP1,SUCO,SDC1,FLT1,FMO1,BRMS1L,IVNS1ABP,PKD2L2,UGGT2,LIMCH1,MYO16,MEGF10,ATP8A2,NPAS3,KDM3B,GC,MCCC2,IKBIP,KLHL20,COMMD6,TMED2,PPIP5K2,MTUS2,ADGRL3,COP1,TDG,CRB1,TMPO,ZNF721,TXK,TENT2,NSD2,KCNT2,PLB1,ANKS1B,ZMYM2,FAM151B,ZBED3-AS1,TMEM178A,ANKDD1B,LAD1,LCP1,LOX" MicroRNA hsa-miR-381:mirSVR_highEffct hsa-miR-381:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.71E-31 2.51E-27 9.83E-30 9.00E-29 82 1519 "BIRC6,NLN,COG6,APAF1,AACS,ATP2B4,CARMIL3,FCRL3,NFKBIA,RAB29,CDKL2,FCHO2,LDB2,PCCA,FAM177A1,CENPC,CFL2,ZNF595,NRXN1,BOD1L1,HECTD1,IL20,CSNK1G3,LRRTM2,BIVM,PTGS2,NUDT12,TBC1D4,OCIAD1,G3BP2,RABGAP1L,RAN,EGLN3,ATG10,TMEM161B,NTN4,TXNDC15,MBNL2,MPHOSPH9,TCTN2,ARSK,ETF1,DLEU1,ABCA11P,ELOVL7,FNIP1,TNFRSF19,POLK,FOXG1,NBEA,UFM1,TADA1,C1orf112,NR5A2,GABRA2,KIF21B,PDS5B,KDM5B,RAPGEF6,OXGR1,MRPS27,CMPK2,NEDD1,KLHL20,GJA3,ADAM17,ADGRA3,ANO4,AP4S1,ACTR6,ZNF721,ATP6V0A2,TRPC4,MZF1,SPTSSA,ANKS1B,ZMYM2,LHX9,KIT,DNAH10,CDK2AP1,LOX" MicroRNA hsa-miR-363:mirSVR_lowEffct hsa-miR-363:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.69E-31 3.03E-27 1.18E-29 1.08E-28 86 1676 "SFTA3,CUL4A,APBB2,DDX55,BLZF1,ARL1,AACS,NCOA1,ASTN1,ATP7B,NRL,CAMK4,SLC5A8,PCDH9,FAM177A1,XPR1,CDK7,SCFD2,RGSL1,PDE4D,PDGFRA,SLC25A3,CFAP54,SMIM14,HOMER1,EPGN,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SPATA18,SREK1,LOC439933,CEP350,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DNMT3A,DTD2,CLIP4,POLR1D,SPATA9,TBC1D19,GP6,FAM172A,DEPDC4,STK32B,DNAJC27,PCGF3,FCAR,FOXG1,RASA3,FBXO11,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,CMPK2,ERBIN,IKBIP,STRN,ADAM17,METAP2,STON1,EML4,KMT5C,RNF17,LINC01551,ADAMTS19,HMGCR,TMEM174,VRK2,YTHDC2,IRF1,TMEM178A,DIAPH3" MicroRNA hsa-miR-107:mirSVR_lowEffct hsa-miR-107:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.76E-31 3.06E-27 1.19E-29 1.09E-28 93 1955 "SMIM15,ADD1,SLAMF6,SEMA6A,ADCY4,SNX24,RGS5,MCFD2,APC,ARHGAP5,ATP2B4,CADM3,FGFRL1,CD84,FCHO2,CCNB1,CD1E,PAH,PCDH9,CDK7,CDK17,GLT1D1,CCDC122,ITGBL1,PMCH,AKAP6,GNPTAB,CSNK1G3,NOS1AP,ZNF586,DGKQ,PIGG,DMXL1,CEP350,SACS,G3BP2,RNF219,RAN,B3GLCT,ARGLU1,TMEM161B,OGFOD2,SLC9C2,RGS4,TMEM33,LRPPRC,LGR6,MAEA,ETF1,DLEU1,ABCA11P,ELOVL7,TMEM156,FCGR2B,GORAB,FLT1,VEZT,SCYL2,CCDC88A,ZNF605,WDCP,MYT1L,PDS5B,ATP8A2,MRPS27,NFASC,MCCC2,LILRB1,TBC1D1,MTUS2,C5orf56,TCF7,EML4,DOCK9,KHNYN,XPO4,BAZ1A,FZD10,ATP6V0A2,UBE2K,GUF1,WDR36,NSD2,ZNF10,KCNT2,ZNF84,PLB1,IRF1,PGAM5,ZBED3-AS1,TTC41P,LMNB1,SPATA13" MicroRNA hsa-miR-103:mirSVR_lowEffct hsa-miR-103:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.76E-31 3.06E-27 1.19E-29 1.09E-28 93 1955 "SMIM15,ADD1,SLAMF6,SEMA6A,ADCY4,SNX24,RGS5,MCFD2,APC,ARHGAP5,ATP2B4,CADM3,FGFRL1,CD84,FCHO2,CCNB1,CD1E,PAH,PCDH9,CDK7,CDK17,GLT1D1,CCDC122,ITGBL1,PMCH,AKAP6,GNPTAB,CSNK1G3,NOS1AP,ZNF586,DGKQ,PIGG,DMXL1,CEP350,SACS,G3BP2,RNF219,RAN,B3GLCT,ARGLU1,TMEM161B,OGFOD2,SLC9C2,RGS4,TMEM33,LRPPRC,LGR6,MAEA,ETF1,DLEU1,ABCA11P,ELOVL7,TMEM156,FCGR2B,GORAB,FLT1,VEZT,SCYL2,CCDC88A,ZNF605,WDCP,MYT1L,PDS5B,ATP8A2,MRPS27,NFASC,MCCC2,LILRB1,TBC1D1,MTUS2,C5orf56,TCF7,EML4,DOCK9,KHNYN,XPO4,BAZ1A,FZD10,ATP6V0A2,UBE2K,GUF1,WDR36,NSD2,ZNF10,KCNT2,ZNF84,PLB1,IRF1,PGAM5,ZBED3-AS1,TTC41P,LMNB1,SPATA13" MicroRNA hsa-miR-627:mirSVR_lowEffct hsa-miR-627:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.02E-31 3.20E-27 1.24E-29 1.13E-28 79 1413 "TMEM132B,ZNF784,BLZF1,ATP2B4,CADM3,CD84,PNP,DAOA,PCSK1,PDE4D,PIWIL1,MRPL57,NRXN1,JAKMIP1,THAP6,C1orf116,LYSMD3,SNCAIP,DNM3,KIAA0040,UBXN2A,SNX17,SPATA18,PIGG,DMXL1,CEP350,CEP120,OCIAD1,DHFR,LINC01257,DNMT3A,RAN,SMC6,FAM228A,RNASEL,GRTP1,KLHL12,DHRS2,STX2,F7,GORAB,TACC3,FBXO11,G2E3,UFM1,SLC30A6,CCDC88A,SLC12A2,NR5A2,ZNF667,EFR3B,MEGF10,NMNAT2,UHRF1BP1L,NPAS3,SRP54,PCDH17,SULT1E1,MAST4,TBC1D1,LILRB4,KMT5A,TDG,COX18,RIMBP2,TECRL,TMEM174,SLAIN1,PAPPA2,JCHAIN,ZNF324B,PLB1,ANKS1B,TDRD3,KIF3C,EP400P1,LAD1,LINC01913,AXDND1" MicroRNA hsa-miR-185:mirSVR_highEffct hsa-miR-185:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.53E-31 3.47E-27 1.34E-29 1.22E-28 77 1342 "MDM4,SLAMF6,NYNRIN,ARL1,B4GALT3,CADM3,FCRL3,DAOA,RILPL1,LDB2,CD1D,CD1E,RFLNA,PCCA,PCDH9,CDK18,PDE6B,CKMT2,CPNE6,AKAP6,RNASE9,GNPTAB,PM20D1,PREPL,CSNK1G3,UBXN2A,FCRL5,ZNF586,DCAF8,DMXL1,KLHL3,COCH,SUPT7L,PARPBP,NR1I3,FAM129A,CRYL1,RNASE2,FAM172A,ABCA11P,TRAPPC13,TNFRSF19,POLK,SUCO,SLC30A6,SLC8A1,TADA1,WDCP,PDS5B,KDM3B,SRP72,GCKR,MCCC2,LILRB1,BRD8,MAST4,PSME4,COP1,NCSTN,TFDP1,GZMH,RAB2B,MAEL,TNR,NPL,HEXB,TPO,PLB1,FAM151B,NPHS2,KCNN2,KIF3C,KIR2DL4,KIR3DL2,AXDND1,CDK2AP1,IFT88" MicroRNA hsa-miR-491-3p:mirSVR_lowEffct hsa-miR-491-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.75E-31 3.59E-27 1.38E-29 1.26E-28 82 1527 "MAP1B,MDM4,CUL4A,APBB2,DDX55,FAM193A,CENPBD1P1,ZNF542P,ATP2B4,ATP4B,STARD13,KCTD12,CD84,RAB29,CAST,LDB2,RFLNA,ZMYM5,PCSK1,PDE4D,MRPL57,AKAP6,TAPT1,COPA,SNCAIP,LACC1,ITSN2,ZFYVE16,SPATA18,FBXL5,RABGAP1L,MTX3,DHFR,PPP2R3C,FAM129A,TMEM161B,LRPPRC,RNF4,STX2,CWC27,SAP18,GMPR2,N4BP2L2,FGF9,POLK,SUCO,FOXG1,SUPT20H,RUBCNL,NBEA,MBIP,SCYL2,IVNS1ABP,CCDC88A,SLC15A4,C1orf112,MRPS14,NR5A2,YPEL5,TMEM183A,ERAP1,ATP8A2,ZNF544,UGT2A1,ATP11A,GOLGA3,ADGRL3,ADGRA3,KHNYN,COX18,GRSF1,CRB1,RASSF6,ADAMTS19,HSP90B1,TENT2,ZNF10,ZNF84,CCDC169,FAM49A,AMTN,MICU2" MicroRNA hsa-miR-578:mirSVR_highEffct hsa-miR-578:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.79E-31 3.61E-27 1.38E-29 1.26E-28 90 1838 "MAP1B,MDM4,ATP6V1G3,ANKRD34B,DDX55,WDR19,STXBP6,AACS,ZNF542P,KCTD12,FCRL3,LINC02347,CBLN3,CAST,AMDHD1,LDB2,CD1E,PDE4D,CENPC,RCBTB2,ITGBL1,CFAP54,NRXN1,LTB4R,THAP6,HOMER1,STRN3,VCAN,C12orf65,CEP135,UBXN2A,ZNF586,ZFYVE16,MATR3,SREK1,DMXL1,OCIAD1,PARPBP,C14orf119,DNMT3A,RASA1,RB1,DTD2,LAP3,PACRGL,SPATA9,ELF1,CWC27,ABCA11P,N4BP2L2,TNFRSF19,PIBF1,FOXG1,FLT1,FTLP10,SGCG,RUBCNL,ALKAL2,STPG4,TADA1,C1orf112,MYO16,PDS5B,OXGR1,SRP72,KLHL20,PCDH17,STRN,BRD8,TBC1D1,PPIP5K2,ADGRL3,ANO4,C5orf56,DOCK9,TDG,TEP1,NT5C1B,GZMH,HAL,HEXB,HMGCR,ZNF876P,ZNF26,KCNT2,ZNF470,PLB1,CAB39L,SPRYD7,AXDND1" MicroRNA hsa-miR-4330:mirSVR_lowEffct hsa-miR-4330:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.16E-31 4.34E-27 1.65E-29 1.51E-28 88 1763 "KIAA1211,COG6,WDR35,MCFD2,APC,NCOA1,ATP1A2,KCTD12,ARHGEF7,BTF3,NFKBIA,CHAMP1,PAH,PCDH9,DCLK1,GLT1D1,RCBTB2,PGGT1B,GPR180,CKMT2,ADGRF3,C1orf116,AKAP6,TTC37,ITSN2,FCRL5,ZFYVE16,CEP350,LINC01257,NR1H4,RNF31,LATS2,MBNL2,SPATA9,TBC1D19,FAM172A,CWC27,SAP18,DNAJC27,ABCA11P,GMPR2,PCGF3,N4BP2L2,PIBF1,SUCO,FBXO11,GFM2,THADA,ARHGEF40,CCDC88A,ZNF605,SLC12A2,DCAF11,EAPP,ZNF274,ERAP1,OXGR1,SRP72,IKBIP,ZBTB37,DHRS4,ADAM17,ADGRA3,ANO4,STON1,DOCK9,RNF212,RNF17,TEP1,CRB1,ZNF721,ATP6V0A2,HEXB,TPO,TXK,GUF1,VRK2,NSD2,YTHDC2,KCNT2,JCHAIN,IL6ST,SPTSSA,ZMYM2,ZBTB41,ZBED3-AS1,DIAPH3,AXDND1" MicroRNA hsa-miR-34a*:mirSVR_lowEffct hsa-miR-34a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.98E-31 4.77E-27 1.81E-29 1.66E-28 90 1845 "MAP1B,MDM4,BIRC6,ACOX3,NLN,TBC1D14,CUL4A,UVSSA,FBRSL1,ARHGAP5,NCOA1,ARHGEF7,NOVA1,DAOA,CAST,CD1D,UHMK1,PCDH9,CDK7,CHD1,VIT,PGGT1B,WDFY2,GPR180,ADGRF3,THTPA,PREPL,TTC37,ITSN2,LRRTM2,DNM3,SREK1,CEP350,GNPDA2,NR1I3,EGLN3,RB1,ARGLU1,TMEM161B,SMC6,RGS12,UGT2A3,ELF1,CWC27,TRAPPC13,PCBD2,FCAR,FCGR3A,TOMM40L,FCGR3B,SUCO,ZCCHC8,TM9SF1,DDX51,GFM2,GABRA2,MYT1L,GAK,OXGR1,DRC1,ANKLE2,SULT1E1,GJA3,GJB2,TMED2,ADGRA3,ACSL6,STON1,DOCK9,XPO4,FCRLA,RNF17,CRB1,LINC01551,AP4S1,ATP6V0A2,NPL,ADAMTS19,TECRL,TXK,GUF1,HTR2A,DCP2,KCNT2,ZNF470,SELENOI,EP400P1,RNASE11,IFT88,MICU2" MicroRNA hsa-miR-412:mirSVR_lowEffct hsa-miR-412:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.72E-31 5.17E-27 1.95E-29 1.79E-28 89 1807 "BIRC6,CUL4A,BLZF1,AACS,CENPBD1P1,CADM3,NFATC4,RAB29,NOVA1,PNP,CACNA1E,MPZL1,CAST,SCARB1,FAM177A1,CDK17,PDE4D,GPR180,CFAP54,LINC01085,AKAP6,STRN3,EPGN,LYSMD3,NGDN,LRRTM2,CEP135,CEP350,PTPRH,DHFR,C12orf42,PARPBP,RAN,RNF31,RASA1,TMEM161B,ZNF329,RGS12,CLIP4,ELK3,BORA,DEPDC4,ABCA11P,F7,TMEM129,FCAR,FGF9,TNFRSF19,FLT1,FBXO11,NBEA,BRMS1L,PLEKHA6,NUBPL,IVNS1ABP,SLC8A1,THADA,TMEM132D,C1orf112,SLC22A4,CHFR,ATP8A2,MRPS27,ERBIN,GJB2,C5orf56,RIPK3,DOCK9,TFDP1,AP4S1,TMPO,ZNF721,HAL,HEXB,GUF1,TENT2,VRK2,HTR2A,DCP2,JCHAIN,ZMYM2,ZBTB41,LHX9,TDRD3,KCNJ9,FIP1L1,KIF3C,EP400P1,AXDND1" MicroRNA hsa-miR-93:mirSVR_highEffct hsa-miR-93:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.09E-30 5.80E-27 2.18E-29 2.00E-28 84 1614 "MDM4,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,SNTG2,FAM177A1,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,NUDT12,CEP120,SACS,G3BP2,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,LRPPRC,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,FBXO11,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,NAAA,ERAP1,NPAS3,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,ARHGEF28,TEP1,AP4S1,RIMBP2,NPL,UBC,ZNF550,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,KIF3C,IFT88" MicroRNA hsa-miR-32:mirSVR_lowEffct hsa-miR-32:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-30 6.07E-27 2.27E-29 2.08E-28 89 1811 "SFTA3,APBB2,DDX55,ARHGAP5,ARL1,AACS,ASTN1,SLC4A4,ATP7B,NRL,CAMK4,RILPL1,SLC5A8,PCDH9,DCLK1,FAM177A1,PDGFRA,SLC25A3,TM9SF2,SMIM14,HOMER1,EPGN,LYSMD3,CEP135,MPHOSPH8,EIF2AK2,NOS1AP,FCRL2,DCAF8,MATR3,SPATA18,SREK1,PTGS2,LOC439933,CEP350,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,DNMT3A,RASA1,CLIP4,POLR1D,SPATA9,LGR6,TBC1D19,STX2,GP6,FAM172A,DEPDC4,STK32B,DNAJC27,PCGF3,FOXG1,RASA3,FBXO11,PLEKHA6,GFM2,SCYL2,FSHR,EFR3B,MEGF10,GABRA2,MYT1L,CMPK2,ANKLE2,ERBIN,IKBIP,STRN,ADAM17,PPIP5K2,METAP2,STON1,EML4,KMT5C,RNF212,RNF17,LINC01551,ADAMTS19,UBE2K,HMGCR,TMEM174,SLAIN1,VRK2,YTHDC2,IRF1,TMEM178A" MicroRNA hsa-miR-431:mirSVR_lowEffct hsa-miR-431:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-30 6.13E-27 2.29E-29 2.10E-28 83 1577 "MDM4,COG6,APAF1,APC,MSH2,NOP14,ASTN1,CD1E,PCCA,PFKFB2,POLN,THAP6,HOMER1,COPA,LYSMD3,CSNK1G3,GALNT9,UBXN2A,FCRL5,EIF2AK2,CEP350,DHFR,PARPBP,EGLN3,FAM129A,TMEM161B,DTD2,SETDB2,PACRGL,MBNL2,MARVELD2,DHRS2,ZNF671,EFS,MAEA,GMPR2,CCDC38,F7,TMEM156,NDUFAF7,N4BP2L2,POLK,SUCO,PAICS,ARHGEF40,SLC15A4,CGREF1,ZNF667,UGGT2,GABRB1,NAAA,HSPH1,KDM3B,NFASC,DRC1,LRCH1,IKBIP,KLHL20,MIMT1,ANO4,ACSL6,STON1,KHNYN,TFDP1,HAL,HMGCR,TMEM174,NLRP8,PAPPA2,KCNT2,PLB1,ANKS1B,ZMYM2,LHX9,ZBED3-AS1,CHPT1,LAD1,LCP1,LINC00442,RMST,ZDHHC20,LMNB1,ZNF304" MicroRNA hsa-miR-892a:mirSVR_lowEffct hsa-miR-892a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.38E-30 7.36E-27 2.74E-29 2.51E-28 88 1776 "MCC,ATP6V1G3,WDR35,MSH2,CCDC181,ZNF542P,STARD13,KCTD12,BCL2L2,CD84,NOVA1,TAF1B,CAST,CHAMP1,CD1D,CD1E,PCCA,PCDH9,RGSL1,PDE4D,GLT1D1,ZNF595,PIGR,LINC01085,NCR1,ANAPC4,AKAP6,FAM163A,RCHY1,LRRTM2,DNM3,FCRL5,EIF2AK2,DCAF8,PIGG,PTGS2,DMXL1,DHX9,PTPRC,OCIAD1,RABGAP1L,DHFR,SUPT7L,DNMT3A,FAM129A,RASA1,FAM228A,KLHL12,CWC27,DLEU1,TOMM40L,PIBF1,POLK,FLT1,CCDC92,PLEKHA6,ALKAL2,SLC8A1,ARHGEF40,SLC12A2,WDCP,C1orf112,DCAF11,PDS5B,NAAA,KDM3B,IKBIP,SULT1E1,PPARGC1A,PSME4,ATP11A,MTUS2,EML4,CRB1,ZBTB49,LINC01551,RIMBP2,MAEL,ADAMTS19,TENT2,WDR36,YTHDC2,JCHAIN,IRF1,ZBTB41,LHX9,CHPT1,LINC01913" MicroRNA hsa-miR-624:mirSVR_highEffct hsa-miR-624:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-30 8.07E-27 2.99E-29 2.74E-28 74 1252 "MCC,ADD1,KIAA1211,HOMEZ,APAF1,CENPBD1P1,RAB29,NOVA1,CAST,CHAMP1,LDB2,CD1E,PCDH9,CDK17,RGSL1,PDGFRA,CFL2,PGGT1B,NRXN1,PIK3C2B,ATAD2B,UGT2B28,AKAP6,LYSMD3,IL20,PSMA6,BIVM,CEP350,DHFR,TSEN15,NR1H4,B3GLCT,RASA1,ARGLU1,RNASEL,EFNA5,GRTP1,BORA,DLEU1,ADGRV1,GORAB,FNIP1,N4BP2L2,FGF9,PIBF1,SDC1,FOXG1,FLT1,G2E3,NBEA,UFM1,IVNS1ABP,TADA1,CCDC88A,SLC12A2,C1orf112,MYT1L,PPARGC1A,ZNF544,METAP2,ADGRL3,C5orf56,KMT5C,CRB1,HEXB,KLF12,TRPC4,ZNF84,ZNF140,ANKS1B,ZMYM2,FIP1L1,CAB39L,PABPN1" MicroRNA hsa-miR-592:mirSVR_lowEffct hsa-miR-592:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-30 8.91E-27 3.28E-29 3.01E-28 84 1624 "ABL2,MCC,BIRC6,KIAA1211,SLAMF6,COG6,SEMA6A,APAF1,ARHGAP5,AACS,ZNF542P,KCTD12,FGFRL1,BCL2L2,BTF3,RFLNA,CHD1,PGGT1B,WDFY2,COPA,RCHY1,TOGARAM2,SYCP3,CLOCK,SNCAIP,C12orf65,CEP135,KIAA0040,PRKD1,EIF2AK2,COG3,LOC439933,DNMT3A,RASA1,RB1,ZNF329,RGS4,TMEM33,POLR1D,NTN4,PACRGL,RNASEL,MARVELD2,FCAMR,TBC1D19,STX2,ARSK,DLEU1,DNAJC27,TMEM129,FLT1,NUBPL,N4BP2,SLC22A4,EFR3B,MEGF10,KIF21B,KDM5B,NMNAT2,NAAA,PCDH17,BRD8,COX7B2,METAP2,LILRB4,STON1,DOCK9,TFDP1,CRB1,GPR161,TMPO,UBE2K,HPCAL1,TENT2,WDR36,IGF1,MZF1,ZNF470,TMEM178A,TTC41P,SLAMF9,LINC01913,LMNB1,CDK2AP1" MicroRNA hsa-miR-20b*:mirSVR_lowEffct hsa-miR-20b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-30 8.93E-27 3.28E-29 3.01E-28 79 1435 "COG6,STARD13,CD84,LINC02347,DAOA,SLC5A8,ZNF664,CDK17,CHD1,NRXN1,ADGRF3,THAP6,HOMER1,AKAP6,COPA,HEATR5A,LYSMD3,SNCAIP,VCAN,SNX17,DMXL1,CEP350,COCH,PTPRC,RABGAP1L,SLC35F6,PARPBP,RASA1,MBNL2,KLHL12,LGR6,STX2,EFS,ARSK,CWC27,ELOVL7,USP44,FCAR,RELL1,FOXO1,FLT1,FBXO11,NUBPL,PAICS,SCYL2,CCDC88A,SLC12A2,N4BP2,C1orf112,NMNAT2,NAAA,ZNF274,IQGAP2,ERAP1,DRC1,IKBIP,SULT1E1,PPARGC1A,MAST4,ZNF544,UTP20,ADAM17,ACSL6,STON1,TGM1,AP4S1,BAZ1A,UBE2K,TECRL,ZNF550,HSD17B4,HTR2A,NSD2,KCNT2,IL6ST,PLB1,ANKS1B,KIF2A,AXDND1" MicroRNA hsa-miR-613:mirSVR_lowEffct hsa-miR-613:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.77E-30 9.41E-27 3.45E-29 3.16E-28 89 1822 "TMEM132B,ADD1,SEMA6A,ARL1,KCTD12,BCL2L2,MPZL1,CD1E,PCCA,CDK17,CFAP54,NRXN1,CFAP45,BOD1L1,THAP6,LYSMD3,CLOCK,CRHBP,NGDN,BRI3BP,LRRTM2,KIAA0040,EIF2AK2,SPATA18,COG3,SUPT7L,RAN,FAM129A,B3GLCT,ARGLU1,SMC6,ELF1,SNORA49,MARVELD2,ZNF671,FAM172A,ARSK,CWC27,STK32B,ABCA11P,SH3YL1,FCGR2B,LRRN2,SUCO,FLT3,SUPT20H,RUBCNL,FBXO11,G2E3,NUBPL,SLC30A6,TADA1,SLC12A2,TMEM132D,LIMCH1,CYP1B1-AS1,CIDEB,GAK,ZNF274,MRPS27,NFASC,SRP72,TMED2,SCFD1,ARHGEF28,DOCK9,TDG,RNF17,TEP1,CRB1,ACTR6,RIMBP2,TNR,HEXB,KLF12,TXK,DCP2,YTHDC2,ZNF26,MZF1,IL6ST,ANKS1B,ZBTB41,FAM49A,ZBED3-AS1,LMLN,FIP1L1,KIR2DL4,KIR2DS4" MicroRNA hsa-miR-224:mirSVR_highEffct hsa-miR-224:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.82E-30 9.65E-27 3.52E-29 3.23E-28 71 1151 "MATN3,SMIM15,TMEM132B,ARL1,AACS,SLC4A4,KCTD12,TAF1B,CAST,FAM177A1,PDE4D,PDGFRA,PFKFB2,PGGT1B,SLC25A3,GPR180,BOD1L1,AKAP6,STRN3,EPGN,DNM3,ZNF586,IFT172,SNX17,BIVM,SPATA18,FBXL5,LOC439933,PTPRC,PARPBP,TMEM161B,RGS4,SETDB2,LRPPRC,MBNL2,STX2,SH3YL1,SPON2,GORAB,SUCO,FLT1,VEZT,G2E3,SCYL2,NR5A2,YPEL5,ACIN1,MYT1L,CENPJ,ERAP1,IKBIP,NPFFR2,TMED2,ADAM17,EML4,MSH6,NPL,HEXB,GPN1,HMGCR,ZNF26,C12orf73,IL6ST,PLB1,LHX9,KCNN2,DIAPH3,DNAH10,LINC01913,ZDHHC20,IFT88" MicroRNA hsa-miR-222:mirSVR_lowEffct hsa-miR-222:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-30 1.23E-26 4.48E-29 4.10E-28 78 1405 "MDM4,TMEM132B,SLAMF6,CUL4A,MSH2,ASTN1,ATP2B4,NFATC4,ARHGEF7,MPZL1,RILPL1,MORN2,LDB2,PCDH9,CDK7,PCSK1,PDGFRA,PDE6B,VIT,WDFY2,NRXN1,AKAP6,MPC2,COPA,CRHBP,LRRTM2,DNM3,UBXN2A,FCRL5,ZNF586,MATR3,SPATA18,LOC439933,OCIAD1,PTPRH,TMEM161B,FAM228A,DTD2,LAP3,RNF4,ELF1,MPHOSPH9,FOXG1,STAB2,G2E3,CGREF1,MRPS14,CHFR,MYO16,GABRB1,KDM5B,NAAA,GJB6,KDM3B,TBC1D1,ADGRL3,ANO4,GPR12,RNF212,CRB1,TGFBI,GPR161,LINC01551,GTF3C2,BAZ1A,TMPO,RIMBP2,ADAMTS19,UBE2K,POC5,IGF1,ZNF140,ANKS1B,ZMYM2,ZBTB41,ANKDD1B,AMTN,SKA3" MicroRNA hsa-miR-154:mirSVR_highEffct hsa-miR-154:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.43E-30 1.29E-26 4.67E-29 4.28E-28 62 862 "MDM4,ADD1,ACOX3,ATP7B,ARHGEF7,BTF3,RAB29,ZNF664,PCCA,CFL2,PIWIL1,ADGRF3,HOMER1,CLOCK,IL20,UBXN2A,GLT8D2,BIVM,DMXL1,RABGAP1L,B3GLCT,CRYL1,EIF2D,UGT2A3,KLHL12,MARVELD2,BORA,STK32B,PCGF3,TRAPPC13,FCGR2B,GORAB,FNIP1,MROH9,SUPT20H,TADA1,PUS1,PDS5B,IQGAP2,HSPH1,IKBIP,KLHL20,MIMT1,SULT1E1,GJA3,UGT2A1,INSM2,ADGRA3,ANO4,C5orf56,TDG,CRB1,BAZ1A,ADAMTS19,GUF1,TENT2,KCNT2,CCDC169,LINC00272,DNAH10,TTC7A,LOX" MicroRNA hsa-miR-20a*:mirSVR_highEffct hsa-miR-20a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-30 1.29E-26 4.67E-29 4.28E-28 81 1518 "LRRC43,BIRC6,ACOX3,SLAMF6,ATP6V1G3,CUL4A,APC,MSH2,BLZF1,CD1D,UHMK1,FCRLB,PCCA,CFL2,ZNF595,LINC01085,THAP6,AKAP6,STRN3,MPC2,RCHY1,POLE,GNPTAB,POU2F1,LYSMD3,CLOCK,CSNK1G3,CEP135,MATR3,PIGG,COG3,DMXL1,LOC439933,NUDT12,PTPRC,SUPT7L,PXMP2,RGS12,CRYL1,NTN4,GUSBP3,PACRGL,LATS2,MARVELD2,DLEU1,ABCA11P,N4BP2L2,RELL1,SUCO,VEZT,RUBCNL,FBXO11,C1orf112,TMEM183A,NPAS3,MCCC2,LRCH1,IKBIP,ZBTB37,DHRS4,MAST4,ZNF544,TMED2,COX7B2,METAP2,ADGRA3,C5orf56,TDG,COX18,ZNF721,STARD4,NSD2,YTHDC2,ZNF10,ZMYM2,NPHS2,TMEM178A,TTC41P,AXDND1,IFT88,ZNF304" MicroRNA hsa-miR-1303:mirSVR_highEffct hsa-miR-1303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.09E-30 1.64E-26 5.91E-29 5.41E-28 76 1338 "MATN3,ACOX3,KIAA1211,ANKRD34B,WDR35,ZNF784,BLZF1,AACS,KCTD12,BTF3,NOVA1,DAOA,NFXL1,PCDH9,FAM177A1,PDGFRA,ZNF595,SMIM14,PIK3C2B,PKP1,HOMER1,SYCP3,CSNK1G3,C12orf65,DNM3,BIVM,COCH,SUPT7L,PARPBP,SLC9C2,RGS12,CLIP4,POLR1D,SETDB2,PACRGL,TXNDC15,SH3YL1,TRAPPC13,UTP15,NDUFAF7,GORAB,FOXG1,SELP,GOLGA2P5,RUBCNL,CCDC88A,C1orf112,MRPS14,UGGT2,GABRA2,MYT1L,NMNAT2,CD244,ERAP1,CMPK2,ANKLE2,LRCH1,PPARGC1A,GJB2,ZNF544,ADAM17,ANO4,TCF7,LINC01551,TMPO,NPL,GUF1,NLRP8,HTR2A,DCP2,JCHAIN,ANKS1B,FAM151B,CHPT1,SPRYD7,AXDND1" MicroRNA hsa-miR-299-3p:mirSVR_lowEffct hsa-miR-299-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.17E-30 1.69E-26 6.04E-29 5.53E-28 82 1562 "RALGAPA1,MDM4,ADORA1,NYNRIN,WDR35,SEMA6A,HOMEZ,SNX24,MCFD2,UVSSA,MSH2,ATP1A2,KCTD12,CCNA1,LINC02347,NRL,CAST,RILPL1,CD1E,UHMK1,PCK2,SCFD2,CDK18,RGSL1,PDE4D,VIT,ZNF595,SMIM14,PTPRVP,THAP6,PMCH,C1orf116,STRN3,FAM163A,CLOCK,FAM169A,DNM3,ZFYVE16,SNX17,COG3,LOC439933,LATS2,MARVELD2,DHRS2,ZNF671,CWC27,PCGF3,FCGR3A,FCGR3B,N4BP2L2,TACC3,FOXO1,FTLP10,ZNF605,POTEM,MEGF10,GABRA2,RAPGEF6,MRPS27,KLHL20,MIMT1,ZBTB37,GOLGA3,C5orf56,RIPK3,ARHGEF28,DOCK9,NCSTN,CRB1,RXFP2,VRK2,ZNF10,IGF1,MZF1,PLB1,LHX9,CHPT1,KCNJ9,RMST,AXDND1,SKA3,SPATA13" MicroRNA hsa-miR-2115:mirSVR_lowEffct hsa-miR-2115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.19E-30 1.70E-26 6.06E-29 5.54E-28 91 1918 "ADORA1,KIAA1211,HOMEZ,APAF1,ZNF784,ASCL1,AACS,SLC4A4,KCTD12,CD84,SLC5A6,RAB29,CACNA1E,MPZL1,CAST,ODC1,CD1D,CD1E,UHMK1,PCDH9,DCLK1,CDK17,RGSL1,WDFY2,SLC25A3,THAP6,POLE,TTC37,KIAA0040,NOS1AP,DCAF8,ZFYVE16,SNX17,PIGG,COG3,DMXL1,PTPRC,RABGAP1L,LINC01257,PARPBP,C14orf119,DNMT3A,EGLN3,CLIP4,PACRGL,DCUN1D2,EIF2B1,MPHOSPH9,ARSK,CWC27,DLEU1,ABCA11P,F10,FOXG1,FOXO1,FLT1,HSD17B7,FBXO11,IVNS1ABP,ZNF605,C1orf112,FSHR,EFR3B,KIF21B,PDS5B,RAPGEF6,TMEM183A,ZNF274,GJB6,HSPH1,LPIN1,MAST4,PPIP5K2,ANO4,GPR12,DOCK9,RNF212,RASSF6,TRPC4,GPN1,HSD17B4,ZNF26,KCNT2,NPHS2,ZBED3-AS1,CHPT1,FAM71C,TTC7A,LMNB1,CDK2AP1,ZNF304" MicroRNA hsa-miR-16-1*:mirSVR_highEffct hsa-miR-16-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.47E-30 1.84E-26 6.56E-29 6.01E-28 87 1759 "RALGAPA1,SMIM15,MDM4,NLN,ANKRD34B,APAF1,ASCL1,KCTD12,CDKL2,TAF1B,ODC1,CCNB1,PAH,NFXL1,ZNF664,DCLK1,ZMYM5,PDGFRA,GLT1D1,CFL2,AKAP6,TAPT1,RCHY1,GNPTAB,HEATR5A,CSNK1G3,ITSN2,CEP135,ZNF586,MATR3,SREK1,FBXL5,NUDT12,COCH,RNF219,DNMT3A,B3GLCT,TMEM161B,ZNF329,CLIP4,PACRGL,RNASEL,MBNL2,ARSK,SAP18,ETF1,CLIP1,TRAPPC13,GORAB,N4BP2L2,TNFRSF19,SUCO,FLT1,HSD17B7,RASA3,TADA1,SLC12A2,WDCP,FSHR,YPEL5,EAPP,ERAP1,HSPH1,OXGR1,NPAS3,SRP72,PPARGC1A,PSME4,C5orf56,EML4,AP4S1,GPN1,SLAIN1,TENT2,PAPPA2,STARD4,ZNF10,IL6ST,ANKS1B,ZMYM2,TDRD3,TTC41P,LCP1,RMST,LMNB1,IFT88,LOX" MicroRNA hsa-miR-204:mirSVR_highEffct hsa-miR-204:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.55E-30 1.89E-26 6.69E-29 6.13E-28 83 1603 "SMIM15,SEMA6A,DDX55,ARL1,AACS,ATP2B4,STARD13,NOVA1,CACNA1E,FCHO2,PCDH9,FAM177A1,PDE4D,VIT,PGGT1B,CFAP54,ATAD2B,UGT2B28,AKAP6,LACC1,DCAF8,PSME1,PIGG,COG3,FBXL5,LOC439933,COCH,OCIAD1,G3BP2,RABGAP1L,PARPBP,TSEN15,DTD2,CLIP4,SETDB2,LATS2,GRTP1,BORA,CWC27,DLEU1,ELOVL7,TMEM156,NDUFAF7,FNIP1,RELL1,POLK,SUCO,FLT3,VEZT,NBEA,ALKAL2,SLC30A6,ZNF605,DCAF11,GABRA2,MYT1L,ZNF274,ERAP1,HSPH1,SRP72,LRCH1,ERBIN,PCDH17,MIMT1,PPARGC1A,ADAM17,METAP2,NCSTN,RNF17,GPR161,GTF2H3,GZMH,TMPO,NPL,GPN1,ARHGAP30,GUF1,CCDC190,ZMYM2,LINC00272,ZBED3-AS1,TTC41P,SPRYD7" MicroRNA hsa-miR-335:mirSVR_lowEffct hsa-miR-335:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-30 1.97E-26 6.98E-29 6.39E-28 92 1963 "MDM4,HOMEZ,EP400,PPFIA4,FBRSL1,NOP14,FAM193A,AACS,SLC4A4,NLRP4,ATP2B4,BCL2L2,CD84,LINC02347,PNP,CDKL2,MPZL1,FCHO2,CD1E,SCARB1,PCK2,FAM177A1,CDK7,PDE4D,PDGFRA,SLC25A3,COLEC11,LINC01085,BOD1L1,PTPRVP,STRN3,COPA,DNM3,UBXN2A,MPHOSPH8,PRKD1,FBXL5,PTPRC,F11R,RABGAP1L,PPP2R3C,NR1I3,DNMT3A,B3GLCT,ATG10,CLIP4,KIRREL1,ELK3,MARVELD2,TCTN2,GP6,DEPDC4,DRAM1,F7,SLC22A17,TOMM40L,LRRN2,STAB2,RASA3,SLC34A2,TADA1,TMEM132D,NR5A2,YPEL5,LIMCH1,MYT1L,PDS5B,JPH4,ATP8A2,NPAS3,CMPK2,NEDD1,PCDH17,MAST4,PPIP5K2,GPR18,ARHGEF28,STON1,KMT5A,TDG,AP4S1,TMPO,RIMBP2,TNR,UBE2K,TXK,SLAIN1,IRF1,ZBED3-AS1,NUAK2,TTC7A,IFT88" MicroRNA hsa-miR-139-5p:mirSVR_lowEffct hsa-miR-139-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-30 2.07E-26 7.29E-29 6.68E-28 89 1842 "ABL2,SMIM15,APBB2,APC,BLZF1,SLC4A4,ZNF542P,STARD13,NOVA1,CBLN3,MPZL1,AMDHD1,FCHO2,CHAMP1,CCNB1,SCFD2,CENPC,PFKFB2,PGGT1B,MRPL57,NUP37,HOMER1,AKAP6,STRN3,SNCAIP,DNM3,PRKD1,PIGG,COG3,RABGAP1L,GNPDA2,SUPT7L,NR1H4,DNMT3A,B3GLCT,RNF31,RB1,TMEM161B,OGFOD2,TMEM33,CLIP4,LRPPRC,PACRGL,ELF1,DHRS2,DRAM1,EFS,TRAPPC13,N4BP2L2,RELL1,FOXG1,HSD17B7,FBXO11,UFM1,PKD2L2,SLC15A4,C1orf112,MYO16,MEGF10,MYT1L,PDS5B,RAPGEF6,CENPJ,EAPP,TMEM183A,ATP8A2,KDM3B,LRCH1,PPARGC1A,MAST4,UGT2A1,INSM2,TMED2,STON1,GRSF1,ZBTB49,AP4S1,MAEL,ATP6V0A2,ZNF550,SLAIN1,WDR36,ZMYM2,IRF1,LHX9,FIP1L1,KIF2A,KIT,ZNF304" MicroRNA hsa-miR-3190-3p:mirSVR_lowEffct hsa-miR-3190-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.93E-30 2.09E-26 7.33E-29 6.71E-28 88 1802 "SFTA3,MCC,EP400,RGS5,APAF1,MSH2,ATP1A2,ATP12A,MYH6,CD84,NOVA1,DAOA,CACNA1E,FCGR2C,PCDH9,ZMYM5,CDK18,CHD1,CPNE6,THAP6,AKAP6,STRN3,TOGARAM2,CLOCK,NCOR2,DCAF8,ZFYVE16,DCT,PTPRC,PARPBP,C14orf119,DNMT3A,SLC9C2,RGS12,ELK3,ETF1,DLEU1,GMPR2,PCGF3,SH3YL1,FCGR3A,TOMM40L,FCGR3B,FGF9,POLK,STAB2,TM9SF1,FBXO11,SCYL2,PUS1,NMNAT2,ATP8A2,NFASC,MCCC2,LRCH1,MIMT1,COMMD6,ZBTB37,GOLGA3,ADGRL3,GPR12,RIPK3,EML4,DOCK9,NCSTN,CRB1,ZBTB49,AP4S1,RIMBP2,TNR,TPO,ZNF550,VRK2,IGF1,MZF1,TADA2B,ZNF470,SELENOI,CHPT1,FIP1L1,KIF3C,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,RMST,LIG4" MicroRNA hsa-miR-19a*:mirSVR_highEffct hsa-miR-19a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.55E-30 2.42E-26 8.46E-29 7.75E-28 74 1274 "ABL2,KIAA1211,WDR35,SEMA6A,SNX24,CDKL4,BLZF1,CAST,FCGR2C,ZMYM5,CFL2,ITGBL1,NRXN1,LTB4R,THAP6,RCHY1,CLOCK,ITSN2,IFT172,NUDT12,PTPRC,GNPDA2,DNMT3A,RB1,SMC6,EIF2D,RNASEL,LATS2,EIF2B1,CWC27,ABCA11P,ADGRV1,TOMM40L,FNIP1,POLK,SDC1,FLT1,FMO1,VEZT,BRMS1L,SCYL2,IVNS1ABP,UGGT2,LIMCH1,MEGF10,KDM3B,GC,MCCC2,IKBIP,KLHL20,COMMD6,TMED2,PPIP5K2,ADGRL3,COP1,RASSF6,TMPO,ZNF721,TXK,TENT2,NSD2,KCNT2,JCHAIN,PLB1,ANKS1B,ZMYM2,FAM151B,TDRD3,ZBED3-AS1,TMEM178A,ANKDD1B,LAD1,LCP1,LOX" MicroRNA hsa-miR-500b:mirSVR_lowEffct hsa-miR-500b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.58E-30 2.44E-26 8.50E-29 7.78E-28 83 1609 "ANKRD34B,COG6,NYNRIN,MSH2,ZNF784,ATP2B4,B4GALT3,BTF3,NOVA1,MPZL1,ZMYM5,PDE6B,CHD1,VIT,POU2F1,EPGN,LYSMD3,BRI3BP,NOS1AP,FCRL2,DCAF8,IFT172,MATR3,BIVM,SREK1,TBC1D4,PTPRC,PPP2R3C,DNMT3A,SLC9C2,LAP3,PACRGL,TXNDC15,MBNL2,ELK3,MARVELD2,TBC1D19,ETF1,ABCA11P,SLC22A17,PCBD2,PIBF1,POLK,FLT1,FTLP10,TM9SF1,PKD2L2,SLC15A4,C1orf112,UGGT2,SNRPF,NAAA,MCCC2,NEDD1,IKBIP,C5orf56,GPR12,EML4,KMT5A,COX18,TFDP1,CRB1,AP4S1,BAZ1A,MAEL,SLAIN1,HSD17B4,PAPPA2,VRK2,WDR36,TADA2B,ZNF470,ZNF84,ANKS1B,FAM151B,CHPT1,DIAPH3,LAD1,LCP1,AXDND1,IFT88,MICU2,SPATA13" MicroRNA hsa-miR-154:mirSVR_lowEffct hsa-miR-154:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.71E-30 3.57E-26 1.24E-28 1.14E-27 77 1391 "MATN3,KIAA1211,NLN,COG6,SNX24,MSH2,BLZF1,WDR19,ASCL1,ATP1A2,KCTD12,NOVA1,UHMK1,PAH,XPR1,GPR180,CFAP54,CFAP45,AKAP6,SNCAIP,BRI3BP,CSNK1G3,VCAN,LRRTM2,CEP135,FCRL5,CTSG,ZNF586,MATR3,NUDT12,CEP120,OCIAD1,LINC01257,PPP2R3C,ELK3,LGR6,DRAM1,CWC27,ETF1,CLIP1,UTP15,FOXG1,VEZT,ZCCHC8,FBXO11,BRMS1L,THADA,ZNF605,C1orf112,MEGF10,RAPGEF6,NPAS3,NFASC,GC,PCDH17,GJB2,PPIP5K2,ADGRL3,STON1,DOCK9,KHNYN,XPO4,TEP1,LINC01551,TMPO,HAL,SLAIN1,NSD2,ZNF10,PLB1,FAM49A,CHPT1,CAB39L,KIF3C,FAM71C,LMNB1,IFT88" MicroRNA hsa-miR-223:mirSVR_highEffct hsa-miR-223:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.78E-30 3.61E-26 1.25E-28 1.14E-27 65 974 "SMIM15,APC,SLC4A4,RILPL1,SCARB1,XPR1,CDK17,SLC25A3,CFAP54,SNX6,HOMER1,AKAP6,RCHY1,LACC1,C12orf65,DDX59,SREK1,NUDT12,TBC1D4,PTPRC,SACS,RABGAP1L,GNPDA2,ATG10,RASA1,RB1,MBNL2,DHRS2,ETF1,ABCA11P,TACC3,POLK,FOXG1,FOXO1,RUBCNL,BRMS1L,PLEKHA6,SLC8A1,PKD2L2,GABRA2,PDS5B,CENPJ,HSPH1,SRP54,LRCH1,PPARGC1A,GJA3,MAST4,TMED2,METAP2,ANO4,DOCK9,SLC7A8,RASSF6,TMPO,MAEL,HSP90B1,GUF1,IL6ST,ANKS1B,ZMYM2,KCNJ9,ANKDD1B,LETM1,AXDND1" MicroRNA hsa-miR-2115:mirSVR_highEffct hsa-miR-2115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.19E-30 3.82E-26 1.32E-28 1.20E-27 65 975 "MDM4,ANKRD34B,APC,FAM193A,NFATC4,CCNA1,DAOA,CAMK4,FAM177A1,PDGFRA,CENPC,PFKFB2,NRXN1,JAKMIP1,RCHY1,GNPTAB,LYSMD3,SNCAIP,CSNK1G3,FCRL5,GNPDA2,TSEN15,RAN,RB1,MEMO1,GRTP1,ETF1,DNAJC27,F7,TOMM40L,N4BP2L2,FGF9,POLK,SUCO,SDC1,MROH9,VEZT,G2E3,UFM1,ARHGEF40,GABRA2,GABRB1,KDM5B,JPH4,CENPJ,ERAP1,NPAS3,DRC1,MCCC2,ERBIN,ZNF544,ATP11A,ARHGEF28,KMT5C,MSH6,TMPO,NPL,TECRL,YTHDC2,JCHAIN,PLB1,KCNN2,EP400P1,AXDND1,MICU2" MicroRNA hsa-miR-1290:mirSVR_highEffct hsa-miR-1290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.20E-30 3.83E-26 1.32E-28 1.20E-27 82 1581 "RALGAPA1,MATN3,MDM4,SLAMF6,COG6,CUL4A,RGS5,ARHGAP5,SLC4A4,ZNF542P,ATP2B4,KCTD12,ATP7B,ARHGEF7,NOVA1,CAMK4,AMDHD1,FCHO2,CD1E,RGSL1,NRXN1,LINC01085,HECTD1,THAP6,VCAN,LRRTM2,DNM3,PRKD1,FCRL5,OCIAD1,PARPBP,PPP2R3C,RNF219,DNMT3A,EGLN3,RASA1,TMEM161B,DTD2,LAP3,EFNA5,RNF4,MBNL2,SPATA9,KLHL12,DNAJC27,PCGF3,TOMM40L,GORAB,POLK,CCDC88A,ZNF667,GABRB1,PDS5B,NPAS3,CMPK2,MCCC2,LRCH1,MIMT1,NMU,ZNF544,ADGRA3,ANO4,GPR161,HEXB,UBE2K,GUF1,SLAIN1,ZNF876P,VRK2,HTR2A,DCP2,SPTSSA,ZMYM2,IRF1,LHX9,KIR2DS4,RNASE11,MFSD2B,LINC01913,FAM71C,SPRYD7,LOX" MicroRNA hsa-miR-4326:mirSVR_lowEffct hsa-miR-4326:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.86E-30 4.18E-26 1.43E-28 1.31E-27 85 1700 "RALGAPA1,ATP6V1G3,UVSSA,NCOA1,NLRP4,STARD13,PPP1R12B,NFATC4,CBLN3,CDKL2,CD1D,RFLNA,ZNF664,DCLK1,CDK18,CHD1,ZNF595,SLC25A3,COLEC11,PKP1,BOD1L1,JAKMIP1,THAP6,AKAP6,MPC2,COPA,RNASE9,VCAN,ITSN2,KIAA0040,NOS1AP,PIGG,COG3,OCIAD1,SUPT7L,RNF219,ATG10,RASA1,RGS12,CRYL1,SETDB2,ELK3,KLHL12,MPHOSPH9,LGR6,MARVELD2,EFS,F10,ARL6IP4,TOMM40L,PEAR1,FOXO1,STAB2,SGCG,BRMS1L,PKD2L2,C1orf112,FSHR,LIMCH1,RAPGEF6,ERAP1,GJB6,MCCC2,PPARGC1A,SPIC,C5orf56,TCF7,ARHGEF28,NCSTN,LINC01551,TMPO,NPL,HEXB,UBE2K,TRPC4,TECRL,HSD17B4,ZNF10,IGF1,IL6ST,SPTSSA,CCDC190,ZMYM2,ANKDD1B,RPGRIP1" MicroRNA hsa-miR-514b-3p:mirSVR_lowEffct hsa-miR-514b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.29E-30 4.41E-26 1.51E-28 1.38E-27 83 1623 "RALGAPA1,BIRC6,KIAA1211,WDR35,SEMA6A,ARL1,NEDD8,ADGRD1,NOVA1,CHAMP1,CD1D,RFLNA,SLC5A8,PCSK1,PDE4D,CHD1,PIK3C2B,C1orf116,AKAP6,FAM163A,SNCAIP,VCAN,CEP135,PRKD1,FCRL5,DCAF8,MATR3,PTGS2,FBXL5,LOC439933,OCIAD1,F11R,FAM129A,RASA1,ZNF329,EIF2B1,ELF1,LGR6,ZNF671,ARSK,TRAPPC13,FGF9,STAB2,SUPT20H,BRMS1L,ZNF446,TADA1,TMEM132D,MYT1L,PDS5B,NAAA,TMEM183A,ATP8A2,SRP72,ANKLE2,LPIN1,ZNF544,ADAM17,ACSL6,TFDP1,CRB1,TGFBI,ZBTB49,MAEL,ADAMTS19,UGT2B7,ZNF876P,TENT2,VRK2,WDR36,ZNF10,KCNT2,ZMYM2,ZBTB41,PGAM5,LHX9,RNASE11,LETM1,RMST,IFT88,PABPN1,MICU2,ZNF304" MicroRNA hsa-miR-19b:mirSVR_highEffct hsa-miR-19b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.35E-30 4.44E-26 1.51E-28 1.38E-27 80 1508 "MATN3,MDM4,ACOX3,KIAA1211,WDR35,APAF1,ATP1A2,ATP12A,CD84,DAOA,CAST,UHMK1,PDE4D,GLT1D1,CFL2,JAKMIP1,HOMER1,STRN3,GNPTAB,CLOCK,NGDN,SNCAIP,LRRTM2,DNM3,DCAF8,SNX17,COG3,CEP350,SACS,G3BP2,WDR1,PARPBP,RASA1,AASDH,CLIP4,MEMO1,EIF2D,ELK3,KLHL12,MPHOSPH9,SAP18,STK32B,ABCA11P,CLIP1,F10,FCAR,TNFRSF19,SUCO,SDC1,FLT1,VEZT,NBEA,PAICS,IVNS1ABP,SLC8A1,CCDC88A,YPEL5,LIMCH1,MYT1L,FAM114A1,RBKS,LRCH1,KLHL20,NPFFR2,MAST4,INSM2,C5orf56,RAB2B,FZD10,ZNF721,NPL,ADAMTS19,UBE2K,TXK,SLAIN1,TENT2,ANKS1B,LMLN,RMST,AXDND1" MicroRNA hsa-miR-767-5p:mirSVR_lowEffct hsa-miR-767-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.48E-30 5.04E-26 1.71E-28 1.56E-27 81 1549 "MCC,ADD1,FBRSL1,MSH2,AACS,ZNF542P,ATP2B4,STARD13,BCL2L2,CD84,NFKBIA,DAOA,SCARB1,DCLK1,CDK17,PIGR,LINC01085,ATAD2B,PTPRVP,AKAP6,STRN3,TAPT1,COPA,VCAN,UBXN2A,MPHOSPH8,NOS1AP,IFT172,MATR3,SNX17,SREK1,RABGAP1L,SUPT7L,PXMP2,LINC01257,PARPBP,RGS12,SETDB2,EFNA5,TXNDC15,KIRREL1,ARSK,STK32B,PCGF3,F7,TOMM40L,VEZT,NBEA,BRMS1L,CHFR,CYP1B1-AS1,TMEM183A,ERAP1,HSPH1,KDM3B,RBKS,NEDD1,LILRB1,GJA3,PPIP5K2,ADGRA3,C5orf56,ARHGEF28,KMT5C,TEP1,MSH6,LINC01551,AP4S1,UBE2K,HPCAL1,YTHDC2,IGF1,PLB1,CCDC190,IRF1,LHX9,LMLN,FAM71C,NUAK2,AXDND1,IFT88" MicroRNA hsa-miR-196a*:mirSVR_lowEffct hsa-miR-196a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.80E-30 5.21E-26 1.76E-28 1.61E-27 87 1785 "LRRC43,MDM4,WDR35,APAF1,DDX55,ARHGAP5,NOP14,ATP2B4,NFATC4,NOVA1,DAOA,MPZL1,PDGFRA,CCDC122,PGGT1B,GPR180,TSTD1,BOD1L1,POLN,CEP135,FAM169A,MPHOSPH8,PRKD1,CTSG,NOS1AP,DDX59,BIVM,DMXL1,TBC1D4,CEP120,PTPRC,OCIAD1,GNPDA2,PARPBP,RB1,CLIP4,PACRGL,RNF4,MBNL2,MARVELD2,TCTN2,TBC1D19,TRAPPC13,NDUFAF7,FGF9,SDC1,FOXG1,FLT1,HSD17B7,TM9SF1,BRMS1L,SLC8A1,THADA,ARHGEF40,EFR3B,GABRA2,MYT1L,KIF21B,PDS5B,NMNAT2,ATP8A2,MRPS27,NFASC,NEDD1,ERBIN,PCDH17,SULT1E1,LPIN1,GJA3,MAST4,ADGRA3,SPIC,EML4,LINC01551,AP4S1,ACTR6,TRPC4,WDR36,STARD4,ZNF10,CENPH,ZMYM2,ZBED3-AS1,TTC41P,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-144:mirSVR_highEffct hsa-miR-144:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-29 5.41E-26 1.82E-28 1.67E-27 92 1990 "NLN,WDR35,UVSSA,APAF1,ARHGAP5,ARL1,ASCL1,NCOA1,ARHGEF7,PNP,NFXL1,ZNF664,RGSL1,PDGFRA,CFL2,PFKFB2,CCDC122,PGGT1B,CFAP54,BOD1L1,AKAP6,GNPTAB,HEATR5A,CSNK1G3,ITSN2,CEP135,MATR3,SREK1,COG3,FBXL5,LOC439933,CEP350,NUDT12,SACS,SUPT7L,FAM129A,B3GLCT,ATG10,RASA1,RB1,SMC6,IPO4,LRPPRC,RNASEL,MBNL2,MPHOSPH9,TBC1D19,STX2,ARSK,CWC27,ELOVL7,USP44,POLK,SUCO,FOXG1,FLT1,SUPT20H,RASA3,CCDC88A,SLC12A2,PKD2L2,WDCP,MRPS14,FSHR,UGGT2,LIMCH1,MYO16,MEGF10,MYT1L,RAPGEF6,EAPP,OXGR1,NPAS3,PPARGC1A,STRN,TBC1D1,INSM2,ATP11A,PPIP5K2,C5orf56,RNF17,NT5C1B,GRSF1,TMPO,HMGCR,VRK2,KCNT2,CCDC169,ZMYM2,RNASE11,IFT88,PABPN1" MicroRNA hsa-miR-150:mirSVR_lowEffct hsa-miR-150:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-29 6.14E-26 2.06E-28 1.89E-27 91 1952 "MAP1B,MCC,ADD1,COG6,ULK1,MSH2,ZNF784,ARHGAP5,STXBP6,ASCL1,SLC4A4,ZNF542P,ATP4B,MYH7,ATP7B,FGFRL1,ARHGEF7,BTF3,NRL,CD1D,CD1E,ZMYM5,PDGFRA,PGGT1B,PIGR,SNX6,HECTD1,MPC2,TAPT1,SNCAIP,C12orf65,CEP135,DNM3,FCRL2,PIGG,PTPRC,OCIAD1,SACS,PARPBP,NR1I3,DNMT3A,B3GLCT,OGFOD2,SLC9C2,PACRGL,EIF2B1,ZNF671,DRAM1,SAP18,DLEU1,CLIP1,TOMM40L,NDUFAF7,POLK,HSD17B7,SFSWAP,TM9SF1,FBXO11,ARHGEF40,C1orf112,ZNF667,GABRA2,PDS5B,NAAA,ERAP1,NFASC,MCCC2,LILRB1,MAST4,UTP20,METAP2,GOLGA3,LILRB4,GPR161,LINC01551,GTF3C2,MAEL,ADAMTS19,TXK,TENT2,WDR36,NSD2,KCNT2,ZNF470,ZNF84,ZMYM2,LINC00272,CHPT1,FAM71C,PABPN1,LOX" MicroRNA hsa-miR-144*:mirSVR_highEffct hsa-miR-144*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-29 6.35E-26 2.12E-28 1.94E-27 67 1050 "MDM4,APAF1,NCOA1,STARD13,NFATC4,RAB29,NOVA1,CDKL2,CAST,CHAMP1,UHMK1,PCCA,CDK7,CFL2,THAP6,SNCAIP,CEP135,COG3,DCT,PTGS2,NUDT12,TBC1D4,OCIAD1,RASA1,RB1,TMEM161B,SMC6,NTN4,RNASEL,RNF4,MBNL2,ARSK,ADGRV1,PCGF3,GORAB,PIBF1,FOXO1,SUPT20H,G2E3,CCDC88A,MEGF10,MYT1L,NAAA,CD244,UHRF1BP1L,ERAP1,KDM3B,NEDD1,LRCH1,EML4,RNF17,CRB1,GTF2H3,NPL,TECRL,TXK,NSD2,FCRL6,KCNT2,ZNF470,SPTSSA,ANKS1B,LHX9,KCNN2,FIP1L1,KIF3C,TTC41P" MicroRNA hsa-miR-888*:mirSVR_lowEffct hsa-miR-888*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-29 6.66E-26 2.22E-28 2.03E-27 82 1594 "RALGAPA1,MAP1B,MCC,MDM4,BIRC6,ADD1,ANKRD34B,APAF1,MSH2,ASCL1,NCOA1,ZNF542P,ATP4B,FGFRL1,PNP,DCLK1,PCK2,RGSL1,PDE4D,PDGFRA,CHD1,PFKFB2,WDFY2,TSTD1,ATAD2B,TAPT1,LYSMD3,CLOCK,CMTM5,PRKD1,FCRL5,NOS1AP,MATR3,DHX9,PTPRC,WDR1,C14orf119,FAM129A,RASA1,LAP3,SETDB2,LRPPRC,RNASEL,LATS2,ZNF671,EFS,PCGF3,F7,FCGR3A,FCGR3B,VEZT,UFM1,SLC8A1,SLC15A4,NR5A2,UGGT2,GABRA2,MYT1L,PDS5B,RAPGEF6,SRP54,LRCH1,KLHL20,LPIN1,GJA3,ZNF544,RNF212,GRSF1,TFDP1,NPL,UBE2K,NSD2,DCP2,ZNF10,ZFHX2,ZNF84,C12orf73,ANKS1B,LMLN,FIP1L1,RMST,AXDND1" MicroRNA hsa-miR-361-5p:mirSVR_highEffct hsa-miR-361-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.27E-29 6.75E-26 2.24E-28 2.05E-27 74 1295 "RALGAPA1,MAP1B,MCC,MDM4,NDRG2,ADORA1,ANKRD34B,STXBP6,ARHGEF7,BTF3,LINC02347,PCDH9,CDK17,RGSL1,ZNF595,HOMER1,AKAP6,CLOCK,SNCAIP,UBXN2A,EIF2AK2,ZNF586,BIVM,PIGG,SREK1,COCH,G3BP2,MTX3,PPP2R3C,RASA1,RB1,ARGLU1,RNF4,MBNL2,UGT2A3,SNORA53,ELK3,MARVELD2,TBC1D19,STX2,ADGRV1,ELOVL7,TRAPPC13,NDUFAF7,GORAB,VEZT,SLC8A1,CCDC88A,YPEL5,MYO16,MYT1L,ANKLE2,IKBIP,CFHR4,SULT1E1,PPIP5K2,GPR18,YIPF7,CRB1,AP4S1,ATP6V0A2,NPL,UBE2K,GUF1,HTR2A,STARD4,ZNF470,ZMYM2,TMEM178A,CAB39L,LAD1,LCP1,RMST,AXDND1" MicroRNA hsa-miR-206:mirSVR_lowEffct hsa-miR-206:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-29 7.06E-26 2.34E-28 2.14E-27 88 1833 "BIRC6,NLN,MCFD2,ARL1,ATP2B4,BCL2L2,CD84,ARHGEF7,MPZL1,CD1E,PCCA,CDK17,CFAP54,NRXN1,CFAP45,BOD1L1,THAP6,AKAP6,LYSMD3,CLOCK,CRHBP,NGDN,BRI3BP,KIAA0040,SPATA18,COG3,RAN,FAM129A,ARGLU1,SMC6,LRPPRC,ELF1,MARVELD2,ZNF671,FAM172A,ARSK,CWC27,STK32B,DLEU1,ABCA11P,SH3YL1,FCGR2B,FGFR3,FLT3,SUPT20H,RUBCNL,FBXO11,G2E3,NUBPL,SLC30A6,TADA1,SLC12A2,TMEM132D,LIMCH1,CYP1B1-AS1,CIDEB,NMNAT2,GAK,ZNF274,NFASC,SRP72,MCCC2,TMED2,SCFD1,ARHGEF28,DOCK9,TDG,RNF17,TEP1,CRB1,ACTR6,RIMBP2,TNR,KLF12,TXK,SLAIN1,DCP2,YTHDC2,ZNF26,JCHAIN,IL6ST,ANKS1B,ZBTB41,ZBED3-AS1,FIP1L1,KIR2DL4,KIR2DS4,TTC7A" MicroRNA hsa-miR-647:mirSVR_lowEffct hsa-miR-647:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-29 7.10E-26 2.34E-28 2.15E-27 85 1713 "EP400,RGS5,NOP14,ASCL1,AACS,CENPBD1P1,ZNF542P,CADM3,CD84,FCRL3,BTF3,SLC5A6,CBLN3,CAST,SYT2,FCGR2C,CDK7,CDK18,CFL2,CHIT1,PTPRVP,THAP6,AKAP6,COPA,GNPTAB,LYSMD3,SNCAIP,VCAN,LRRTM2,DDX59,ZNF586,ZFYVE16,COG3,DNMT3A,FAM129A,POLR1D,CRYL1,EFNA5,EIF2B1,MPHOSPH9,ZNF671,DRAM1,EFS,FAM81B,SAP18,DNAJC27,ELOVL7,TRAPPC13,TOMM40L,NDUFAF7,POLK,HSD17B7,STAB2,G2E3,DDX51,ZNF446,ARHGEF40,PKD2L2,TMEM132D,PUS1,CYP1B1-AS1,TMEM183A,ZNF274,KDM3B,MCCC2,LRCH1,PPARGC1A,ZNF544,TBC1D1,TMED2,TFDP1,CRB1,GPR161,RIMBP2,NPL,HPCAL1,STARD4,ZNF470,ANKS1B,PGAM5,LHX9,KIF2A,TTC41P,DNAH10,PABPN1" MicroRNA hsa-miR-1:mirSVR_lowEffct hsa-miR-1:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-29 7.15E-26 2.35E-28 2.15E-27 87 1793 "MCC,BIRC6,NLN,SEMA6A,MCFD2,ARL1,ATP2B4,BCL2L2,CD84,ARHGEF7,MPZL1,CD1E,PCCA,CDK17,CFAP54,NRXN1,CFAP45,BOD1L1,THAP6,LYSMD3,CLOCK,CRHBP,NGDN,BRI3BP,KIAA0040,EIF2AK2,SPATA18,COG3,RAN,FAM129A,B3GLCT,ARGLU1,SMC6,ELF1,MARVELD2,ZNF671,FAM172A,ARSK,CWC27,STK32B,ABCA11P,SH3YL1,FCGR2B,FLT3,SUPT20H,RUBCNL,FBXO11,G2E3,NUBPL,SLC30A6,TADA1,SLC12A2,TMEM132D,LIMCH1,CYP1B1-AS1,CIDEB,NMNAT2,GAK,ZNF274,MRPS27,NFASC,SRP72,TMED2,SCFD1,ARHGEF28,DOCK9,TDG,RNF17,TEP1,CRB1,ACTR6,RIMBP2,TNR,KLF12,TXK,SLAIN1,DCP2,YTHDC2,ZNF26,JCHAIN,IL6ST,ANKS1B,ZBTB41,ZBED3-AS1,FIP1L1,KIR2DL4,KIR2DS4" MicroRNA hsa-miR-363:mirSVR_highEffct hsa-miR-363:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.44E-29 7.67E-26 2.52E-28 2.30E-27 65 987 "MAP1B,KIAA1211,PITPNM2,CDKL4,ATP2B4,STARD13,BTF3,NOVA1,FCHO2,CD1D,CDK17,CFL2,ZNF595,GPR180,NUP37,JAKMIP1,UGT2B28,HECTD1,STRN3,CRHBP,C12orf65,ZNF586,COG3,DMXL1,G3BP2,FAM129A,LAP3,LATS2,RNF4,ABCA11P,USP44,FNIP1,POLK,SUCO,SUPT20H,BRMS1L,ALKAL2,ZNF605,SLC12A2,MYO16,PDS5B,NAAA,IQGAP2,NPAS3,RBKS,LRCH1,LPIN1,ZNF544,LINC02393,PPIP5K2,GOLGA3,ANO4,GPR12,DOCK9,TMPO,FZD10,ZNF721,TRPC4,UGT2B7,TENT2,KCNT2,CCDC169,RMST,AXDND1,LMNB1" MicroRNA hsa-miR-3128:mirSVR_lowEffct hsa-miR-3128:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-29 7.73E-26 2.53E-28 2.31E-27 89 1876 "MATN3,IL17D,RGS5,PPFIA4,APC,CDKL4,DDX55,BLZF1,NOP14,ASTN1,ZNF542P,STARD13,ATP7B,ARHGEF7,CCNA1,MORN2,CHAMP1,CENPC,GLT1D1,WDFY2,ATAD2B,BOD1L1,C1orf116,CLOCK,CEP135,KIAA0040,PRKD1,PIGG,DMXL1,DHX9,F11R,GNPDA2,PARPBP,C14orf119,FAM129A,RNF31,RASA1,RB1,RGS12,RNF4,TCTN2,DLEU1,ADGRV1,F10,TRAPPC13,TOMM40L,NDUFAF7,N4BP2L2,TNFRSF19,PIBF1,FTLP10,TM9SF1,G2E3,NBEA,BRMS1L,CGREF1,SLC22A5,NR5A2,CYP1B1-AS1,MYO16,ERAP1,HSPH1,RBKS,PCDH17,NMU,GJA3,ADGRL3,ANO4,C5orf56,RIPK3,DOCK9,TDG,RNF17,TEP1,CRB1,ATP6V0A2,HEXB,KLF12,HMGCR,SLAIN1,NSD2,IGF1,ZNF324B,ANKS1B,KCNN2,KIR2DL4,KIR3DL1,KIR3DL2,SKA3" MicroRNA hsa-miR-106b:mirSVR_highEffct hsa-miR-106b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.76E-29 9.34E-26 3.04E-28 2.78E-27 80 1525 "MDM4,BIRC6,ULK1,ARL1,ASTN1,ATP1A2,ATP12A,SLC4A4,ZNF542P,MYH6,ARHGEF7,CCNA1,ADGRD1,DAOA,RILPL1,FCHO2,FAM177A1,PDE4D,PDGFRA,CFL2,BOD1L1,JAKMIP1,THAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,ITSN2,UBXN2A,ZFYVE16,PIGG,FBXL5,CEP120,SACS,GNPDA2,EGLN3,FAM129A,RASA1,RB1,CLIP4,NTN4,RNASEL,TXNDC15,ELK3,ZNF671,DNAJC27,IRF9,RELL1,SUCO,FLT1,HSD17B7,VEZT,ZCCHC8,NBEA,BRMS1L,UFM1,ARHGEF40,CCDC88A,MYT1L,ERAP1,NPAS3,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,ZBTB37,ARHGEF28,RNF17,AP4S1,RIMBP2,NPL,UBC,ZNF470,ANKS1B,IRF1,LHX9,KCNN2,CDK2AP1,IFT88" MicroRNA hsa-miR-2113:mirSVR_lowEffct hsa-miR-2113:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-29 9.35E-26 3.04E-28 2.78E-27 89 1881 "MAP1B,COG6,BLZF1,AACS,CENPBD1P1,NFKBIA,CCNA1,NOVA1,AMDHD1,UHMK1,PCDH9,CDK18,WDR66,RCBTB2,TOGARAM2,DNM3,KIAA0040,GLT8D2,MATR3,BIVM,SPATA18,PSME1,DMXL1,SACS,RABGAP1L,GNPDA2,PARPBP,DNMT3A,FAM129A,LAP3,MEMO1,NTN4,RNASEL,LATS2,UGT2A3,DHRS2,GP6,CWC27,ABCA11P,PCGF3,CLIP1,ELOVL7,PCBD2,PIBF1,FOXO1,FLT1,SUPT20H,SLC30A6,ADCY10,KIF21B,CD244,GJB6,CMPK2,IKBIP,SULT1E1,ZBTB37,UGT2A1,TMED2,LINC02393,ADGRA3,TCF7,STON1,RNF17,TFDP1,AP4S1,RASSF6,HAL,GPN1,TMEM174,SLAIN1,HSD17B4,TENT2,VRK2,ZNF10,ZFHX2,SELENOI,IL6ST,ZMYM2,ZBTB41,LHX9,TDRD3,TMEM178A,LMLN,FIP1L1,EP400P1,LIG4,LMNB1,CDK2AP1,SPATA13" MicroRNA hsa-miR-424:mirSVR_highEffct hsa-miR-424:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.01E-29 1.07E-25 3.45E-28 3.15E-27 79 1490 "KIAA1211,RGS5,NCOA1,SLC4A4,ATP4B,MYBPC1,BCL2L2,NOVA1,CAMK4,CAST,CD1D,PCDH9,CDK17,GLT1D1,CHD1,GPR180,ITGBL1,CFAP54,NRXN1,CFAP45,JAKMIP1,THAP6,CLOCK,PREPL,IL20,LRRTM2,FCRL2,DCAF8,SREK1,COCH,RNF219,TMEM161B,CLIP4,LATS2,MBNL2,SPATA9,LGR6,TBC1D19,ABCA11P,TMEM156,SPON2,FGF9,LRRN2,TNFRSF19,SUCO,FLT3,UFM1,IVNS1ABP,ARHGEF40,CCDC88A,ZNF605,SLC15A4,SLC22A4,YPEL5,MYT1L,NPAS3,NFASC,LRCH1,PCDH17,INSM2,RNF212,COP1,NT5C1B,CRB1,FZD10,ADAMTS19,GPN1,TXK,HTR2A,ANKS1B,ZMYM2,CHPT1,KIF2A,KIR2DS4,LINC01913,LCP1,RMST,SPRYD7,LMNB1" MicroRNA hsa-miR-626:mirSVR_lowEffct hsa-miR-626:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-29 1.07E-25 3.45E-28 3.15E-27 79 1490 "SMIM15,BIRC6,ADD1,COG6,SEMA6A,CUL4A,APBB2,ARL1,KCTD12,ARHGEF7,CCNA1,LINC02347,NOVA1,SNTG2,ZNF664,RCBTB2,THAP6,TAPT1,GNPTAB,THTPA,HEATR5A,DNM3,KIAA0040,DDX59,ZNF586,SNX17,SPATA18,EPS8L1,COG3,F11R,SUPT7L,WDR1,PARPBP,DNMT3A,EGLN3,ZNF419,TXNDC15,KLHL12,DHRS2,FAM172A,DLEU1,TLR6,N4BP2L2,FGFR3,PEAR1,HSD17B7,RUBCNL,PAICS,ZNF446,POTEM,WDCP,YPEL5,MYT1L,GABRB1,FAM114A1,NAAA,NPAS3,CMPK2,NFASC,LRCH1,KLHL20,LPIN1,GJA3,GJB2,MAST4,TBC1D1,TCF7,EML4,KHNYN,RNF212,FZD10,UBE2K,HMGCR,VRK2,ZBTB41,PGAM5,TTC41P,AXDND1,LOX" MicroRNA hsa-miR-1912:mirSVR_lowEffct hsa-miR-1912:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.08E-29 1.11E-25 3.56E-28 3.26E-27 85 1724 "MCC,ADD1,SLAMF6,COG6,WDR35,SEMA6A,EP400,APBB2,ATP1A2,KCTD12,ATP7B,CARMIL3,LINC02347,RAB29,PNP,FCRLB,SLC5A8,PDE4D,PFKFB2,CHIT1,PGGT1B,ATAD2B,HOMER1,RCHY1,TOGARAM2,THTPA,NGDN,GALNT9,EIF2AK2,SPATA18,PIGG,CEP350,OCIAD1,SLC35F6,NR1H4,DNMT3A,OGFOD2,RGS12,EFNA5,RNF4,MBNL2,TCTN2,DRAM1,ABCA11P,PCGF3,PCBD2,FCAR,TNFRSF19,SUCO,SELP,STAB2,VEZT,FBXO11,PAICS,STPG4,THADA,PKD2L2,C1orf112,DCAF11,SNRPF,CPSF3,MYO16,GABRB1,NMNAT2,CD244,SRP72,GCKR,PCDH17,PPARGC1A,GJA3,TCF7,TDG,ZBTB49,GTF3C2,RAB2B,RIMBP2,TRPC4,GUF1,TMEM174,IL6ST,CCDC169,SLAMF9,NUAK2,TTC7A,IFT88" MicroRNA hsa-miR-190b:mirSVR_highEffct hsa-miR-190b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.19E-29 1.16E-25 3.73E-28 3.41E-27 67 1061 "MAP1B,MATN3,TBC1D14,SNX24,APAF1,NCOA1,ASTN1,KCTD12,TAF1B,CD1E,ZNF664,PCDH9,RGSL1,RCBTB2,MRPL57,NRXN1,UGT2B28,COPA,CLOCK,LRRTM2,DCAF8,DMXL1,NUDT12,G3BP2,TSEN15,TMEM161B,SMC6,REST,RNF4,LGR6,CWC27,SAP18,GMPR2,ELOVL7,SH3YL1,TRAPPC13,FNIP1,TNFRSF19,NBEA,UFM1,IVNS1ABP,ZNF605,P2RX2,MRPS14,MEGF10,IQGAP2,CMPK2,MCCC2,IKBIP,PCDH17,SULT1E1,PPARGC1A,METAP2,ANO4,ARHGEF28,DOCK9,CRB1,AP4S1,HEXB,ADAMTS19,TXK,STARD4,C12orf73,CCDC169,ZNF140,CHPT1,DIAPH3" MicroRNA hsa-miR-4295:mirSVR_highEffct hsa-miR-4295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.19E-29 1.17E-25 3.73E-28 3.41E-27 70 1164 "MATN3,MDM4,BIRC6,KIAA1211,WDR35,ULK1,APAF1,APC,BLZF1,NCOA1,ATP12A,ZNF542P,STARD13,DAOA,CDKL2,CAST,FCHO2,SNTG2,PDGFRA,CFL2,JAKMIP1,HOMER1,FAM53A,GNPTAB,HEATR5A,LYSMD3,CLOCK,DNM3,DCAF8,ZFYVE16,FBXL5,NUDT12,CEP120,RASA1,AASDH,MEMO1,ELK3,MPHOSPH9,SAP18,CLIP1,F10,NDUFAF7,GORAB,N4BP2L2,TNFRSF19,PEAR1,NBEA,SLC8A1,CCDC88A,C1orf112,MYT1L,ERAP1,CMPK2,LRCH1,ERBIN,KLHL20,NPFFR2,INSM2,RNF17,ADAMTS19,UBC,SLAIN1,TENT2,IRF1,LMLN,CAB39L,DIAPH3,RMST,LIG4,LMNB1" MicroRNA hsa-miR-1278:mirSVR_lowEffct hsa-miR-1278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-29 1.22E-25 3.88E-28 3.55E-27 79 1493 "ADD1,SLAMF6,CUL4A,PITPNM2,PPFIA4,MSH2,ARL1,FAM193A,ZNF542P,B4GALT3,ARHGEF7,RAB29,FCHO2,CCNB1,NFXL1,PCDH9,CHD1,SLC25A3,THAP6,AKAP6,NGDN,SNCAIP,CSNK1G3,FAM169A,DNM3,ZNF586,DCAF8,ZFYVE16,MATR3,SPATA18,TBC1D4,G3BP2,RABGAP1L,LINC01257,NR1I3,FAM129A,RASA1,SLC9C2,CLIP4,SETDB2,GUSBP3,EFNA5,MBNL2,DRAM1,SAP18,N4BP2L2,MROH9,FOXO1,SCYL2,PKD2L2,C1orf112,CYP1B1-AS1,GABRA2,MYT1L,PDS5B,ERAP1,SRP54,NFASC,LRCH1,ZNF544,TBC1D1,METAP2,MTUS2,ANO4,ACSL6,ARHGEF28,DOCK9,KHNYN,CRB1,LINC01551,AP4S1,RASSF6,UBE2K,GUF1,WDR36,SELENOI,LMLN,FAM71C,IFT88" MicroRNA hsa-miR-4289:mirSVR_lowEffct hsa-miR-4289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-29 1.30E-25 4.13E-28 3.78E-27 85 1728 "RALGAPA1,SFTA3,MAP1B,IL17D,COG6,BTF3,NOVA1,DAOA,CAST,UHMK1,FCRLB,RFLNA,XPR1,PCSK1,PDE4D,PDGFRA,CHD1,ZNF595,COPA,SNCAIP,CSNK1G3,DNM3,SNX17,BIVM,PSME1,COG3,FBXL5,PTPRC,G3BP2,RAN,B3GLCT,TMEM161B,SMC6,SLC9C2,MEMO1,POLR1D,GUSBP3,ELK3,MARVELD2,DRAM1,F10,TNFRSF19,PIBF1,SUCO,FOXO1,FLT1,VEZT,BRMS1L,IVNS1ABP,CCDC88A,SLC12A2,PKD2L2,C1orf112,YPEL5,MYO16,MYT1L,IQGAP2,GC,RBKS,KLHL20,MIMT1,PPARGC1A,COX7B2,PPIP5K2,ACSL6,NT5C1B,GRSF1,LINC01551,ADAMTS19,GUF1,TMEM174,SLAIN1,TENT2,STARD4,NSD2,IGF1,KCNT2,IL6ST,ANKS1B,NPHS2,LMLN,EP400P1,TTC41P,RMST,LTA4H" MicroRNA hsa-miR-429:mirSVR_highEffct hsa-miR-429:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.67E-29 1.42E-25 4.49E-28 4.11E-27 89 1892 "SMIM15,COG6,CUL4A,MCFD2,DDX55,BLZF1,WDR19,ARL1,STARD13,NOVA1,CAD,CAST,CHAMP1,CD1D,PCSK1,CDK17,CFL2,CHD1,CCDC122,WDFY2,NRXN1,ATAD2B,BOD1L1,HOMER1,TAPT1,COPA,GNPTAB,LYSMD3,LACC1,CSNK1G3,FAM169A,FCRL5,DCAF8,MATR3,CEP350,OCIAD1,SUPT7L,PARPBP,TSEN15,DNMT3A,EGLN3,B3GLCT,ARGLU1,CLIP4,CRYL1,RNASEL,DLEU1,CLIP1,TRAPPC13,FGF9,RELL1,POLK,FOXG1,FOXO1,SUPT20H,FBXO11,G2E3,BRMS1L,MBIP,UFM1,THADA,SLC12A2,NR5A2,ZNF667,UGGT2,KIF21B,ZNF274,MRPS27,NEDD1,IKBIP,COMMD6,MAST4,PSME4,INSM2,METAP2,ADGRL3,C5orf56,ATP6V0A2,SLAIN1,VRK2,SPTSSA,LHX9,CHPT1,TMEM178A,TTC41P,RMST,IFT88,LOX,ZNF304" MicroRNA hsa-miR-194*:mirSVR_lowEffct hsa-miR-194*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.71E-29 1.44E-25 4.55E-28 4.16E-27 91 1975 "MDM4,BIRC6,ADD1,NLN,SEMA6A,EP400,STXBP6,ASTN1,MYH6,PCSK1,C1orf116,FAM163A,HEATR5A,GALNT9,LRRTM2,UBXN2A,DGKQ,EPS8L1,PIGG,PTPRC,DNMT3A,CRYL1,RNASEL,LATS2,RNF4,KIRREL1,KLHL12,LGR6,DHRS2,GP6,ZNF671,MAEA,PCGF3,F10,ARL6IP4,TRAPPC13,FCGR2B,TOMM40L,FNIP1,FGF9,SUCO,PEAR1,FOXO1,VEZT,GOLGA2P5,SLC34A2,NBEA,SLC12A2,WDCP,NR5A2,YPEL5,UGGT2,SNRPF,NMNAT2,RAPGEF6,IQGAP2,MRPS27,KDM3B,NFASC,DRC1,RBKS,LRCH1,ERBIN,MIMT1,DHRS4,TBC1D1,INSM2,ANO4,NCSTN,RIMBP2,TPO,UBE2K,TXK,TMEM174,VRK2,NSD2,YTHDC2,ZNF84,PLB1,LHX9,FAM151B,KIF3C,DIAPH3,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,DNAH10,LINC01913,LINC00442,SPRYD7" MicroRNA hsa-miR-4288:mirSVR_lowEffct hsa-miR-4288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-29 1.57E-25 4.94E-28 4.52E-27 80 1537 "MDM4,ACOX3,KIAA1211,ULK1,BLZF1,ATP1A2,ATP12A,CADM3,CD84,NFATC4,ARHGEF7,PNP,RILPL1,ODC1,CHAMP1,CD1E,SCARB1,SNTG2,ZNF664,PDGFRA,ITGBL1,POLN,POLE,TOGARAM2,LYSMD3,PREPL,LACC1,MATR3,SPATA18,CEP350,PTPRC,PARPBP,EGLN3,RGS4,CLIP4,RNASEL,TXNDC15,MBNL2,TRAPPC12,ZNF256,MARVELD2,CLIP1,F7,ARL6IP4,FNIP1,RELL1,TACC3,SLC8A1,UGGT2,MEGF10,CIDEB,PDS5B,FAM114A1,ATP8A2,RBKS,COMMD6,LPIN1,MTUS2,LILRB4,ANO4,GPR12,RNF17,CRB1,MSH6,AP4S1,ZNF721,HEXB,ADAMTS19,SLAIN1,TENT2,VRK2,WDR36,ZNF470,PLB1,ZMYM2,LHX9,TTC41P,LINC01913,AXDND1,IFT88" MicroRNA hsa-miR-708*:mirSVR_lowEffct hsa-miR-708*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.08E-29 1.64E-25 5.14E-28 4.70E-27 76 1387 "MCC,COG6,TBC1D14,WDR35,CUL4A,RGS5,ARHGAP5,NCOA1,ATP2B4,PPP1R12B,MPZL1,ODC1,XPR1,TM9SF2,BOD1L1,THAP6,AKAP6,MPC2,TAPT1,HEATR5A,CLOCK,VCAN,MATR3,KLHL3,TBC1D4,CEP120,OCIAD1,SACS,GNPDA2,SLC35F6,C14orf119,B3GLCT,RGS4,TMEM33,MEMO1,TXNDC15,TRAPPC12,ELK3,DRAM1,DLEU1,SH3YL1,FCGR3B,GORAB,N4BP2L2,LRRN2,RELL1,PIBF1,POLK,RUBCNL,C1orf112,NR5A2,MYT1L,KDM5B,JPH4,ERAP1,OXGR1,COMMD6,GJA3,ADGRL3,TCF7,COX18,GRSF1,GTF3C2,RAB2B,TMPO,RIMBP2,UBE2K,GUF1,ZNF10,CENPH,JCHAIN,CCDC169,SPTSSA,FIP1L1,KIF2A,RMST" MicroRNA hsa-miR-379*:mirSVR_highEffct hsa-miR-379*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-29 1.76E-25 5.50E-28 5.04E-27 74 1315 "MAP1B,MCC,SMIM15,IL17D,COG6,ARL1,NCOA1,SLC4A4,NLRP4,CDKL2,RILPL1,UHMK1,CDK7,CHD1,ITGBL1,NRXN1,SMIM14,THAP6,HOMER1,AKAP6,TAPT1,COPA,HEATR5A,LYSMD3,CLOCK,CSNK1G3,FAM169A,NUDT12,OCIAD1,RABGAP1L,PPP2R3C,B3GLCT,RB1,REST,LRPPRC,RNASEL,RNF4,ELK3,CWC27,FNIP1,PIBF1,POLK,SUCO,FOXO1,SUPT20H,VEZT,NLRP2,SLC30A6,SLC12A2,C1orf112,RAPGEF6,TMEM183A,ATP8A2,KDM3B,CMPK2,SRP72,SULT1E1,PPARGC1A,TBC1D1,PPIP5K2,METAP2,ADGRA3,ANO4,ADAMTS19,GUF1,YTHDC2,KCNT2,ANKS1B,ZMYM2,IRF1,LHX9,LINC01913,AXDND1,LOX" MicroRNA hsa-miR-599:mirSVR_lowEffct hsa-miR-599:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-29 2.55E-25 7.94E-28 7.27E-27 84 1705 "MAP1B,TMEM132B,RGS5,APBB2,SLC4A4,BTF3,CCNA1,LINC02347,NOVA1,TAF1B,RILPL1,FCGR2C,SCARB1,UHMK1,XPR1,CDK17,PDGFRA,WDFY2,SLC25A3,PIGR,HOMER1,SYCP3,HEATR5A,KIAA0040,BIVM,LOC439933,MTX3,PARPBP,C14orf119,RB1,SMC6,NTN4,MBNL2,UGT2A3,KLHL12,TBC1D19,GP6,DEPDC4,ARSK,CWC27,ABCA11P,CLIP1,PCBD2,FCAR,FNIP1,SUCO,FTLP10,PLEKHA6,ALKAL2,NUBPL,SLC12A2,POTEM,EFR3B,MEGF10,GABRB1,NMNAT2,IQGAP2,CMPK2,LRCH1,TMED2,LINC02393,METAP2,CNTN2,ADGRL3,ADGRA3,KMT5A,DOCK9,COP1,NCSTN,TFDP1,CRB1,LINC01551,AP4S1,TMPO,RIMBP2,ADAMTS19,TMEM174,KCNT2,ZNF470,ZNF324B,PLB1,TDRD3,ZBED3-AS1,KIF2A" MicroRNA hsa-miR-651:mirSVR_lowEffct hsa-miR-651:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-29 2.56E-25 7.95E-28 7.27E-27 79 1510 "KIAA1211,WDR35,SEMA6A,APBB2,BLZF1,ATP4B,BTF3,CBLN3,CHAMP1,UHMK1,PCCA,DCLK1,RGSL1,PDE4D,CFAP54,HECTD1,AKAP6,FAM53A,SYCP3,SNCAIP,DNM3,FCRL5,ZNF586,ZFYVE16,MTX3,NR1H4,SMC6,CLIP4,POLR1D,EIF2D,PACRGL,RNF4,MARVELD2,DHRS2,TBC1D19,FAM172A,PCOTH,ARSK,PCGF3,F10,FCGR3A,HSD17B7,FMO1,FBXO11,ALKAL2,ZNF605,N4BP2,C1orf112,GABRB1,KDM5B,UHRF1BP1L,OXGR1,MCCC2,IKBIP,GJA3,BRD8,INSM2,SCFD1,PPIP5K2,METAP2,ADGRL3,RIPK3,DOCK9,COX18,AP4S1,ACTR6,FZD10,NPL,ADAMTS19,HSP90B1,TECRL,TENT2,NSD2,IGF1,IL6ST,GALP,LHX9,FAM49A,AXDND1" MicroRNA hsa-miR-489:mirSVR_highEffct hsa-miR-489:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.06E-29 2.69E-25 8.33E-28 7.63E-27 62 911 "SLAMF6,SEMA6A,DDX55,NCOA1,ATP12A,B4GALT3,CACNA1E,LDB2,RFLNA,SLC5A8,PDE4D,CENPC,CFL2,PIWIL1,PKP1,THAP6,AKAP6,COPA,RABGAP1L,SUPT7L,C12orf42,C14orf119,NR1H4,SLC9C2,CLIP4,NTN4,LRPPRC,LATS2,UGT2A3,ETF1,TOMM40L,PIBF1,SDC1,MBIP,PAICS,IVNS1ABP,ARHGEF40,TADA1,FSHR,NR5A2,YPEL5,MEGF10,PDS5B,UHRF1BP1L,OXGR1,ANO4,LINC01551,AP4S1,TMPO,HEXB,ADAMTS19,TXK,GUF1,TENT2,STARD4,SPTSSA,CCDC190,KCNN2,DIAPH3,RMST,NUAK2,AXDND1" MicroRNA hsa-miR-3168:mirSVR_lowEffct hsa-miR-3168:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.25E-29 2.79E-25 8.61E-28 7.88E-27 79 1512 "SMIM15,ATP6V1G3,TBC1D14,EP400,MSH2,BLZF1,ARHGAP5,CCDC181,SLC4A4,STARD13,FCRL3,ARHGEF7,NOVA1,PNP,CAST,NFXL1,PCCA,PDE4D,CFAP54,ATAD2B,RCHY1,SYCP3,HEATR5A,LYSMD3,CEP135,PRKD1,FCRL5,ZNF586,MATR3,EPS8L1,SREK1,DMXL1,KLHL3,RABGAP1L,GNPDA2,NR1H4,FAM129A,ATG10,CLIP4,POLR1D,LRPPRC,SPATA9,TBC1D19,ETF1,DLEU1,FCGR3A,FCGR3B,TNFRSF19,PIBF1,FOXG1,UFM1,SLC12A2,PKD2L2,N4BP2,PUS1,MYO16,RAPGEF6,NAAA,IQGAP2,HSPH1,ERBIN,IKBIP,KLHL20,ACSL6,DOCK9,FCRLA,BAZ1A,ADAMTS19,UBE2K,HMGCR,SLAIN1,TENT2,NSD2,IL6ST,CCDC169,SPTSSA,CHPT1,KIF2A,KIR2DL4" MicroRNA hsa-miR-1269:mirSVR_lowEffct hsa-miR-1269:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.42E-29 2.89E-25 8.88E-28 8.13E-27 73 1289 "ANKRD34B,MCFD2,ASTN1,STARD13,CCNA1,MPZL1,CAST,FCRLB,ZNF664,DCLK1,PDGFRA,ADGRF3,POLN,AKAP6,POU2F1,CLOCK,PREPL,PTGS2,PTPRC,SUPT7L,LINC01257,NR1H4,DNMT3A,RNF31,RB1,AASDH,RNF4,EIF2B1,KLHL12,MAEA,N4BP2L2,TNFRSF19,FOXG1,FOXO1,FLT1,VEZT,TMEM175,DDX51,GFM2,ARHGEF40,WDCP,C1orf112,MYO16,GABRB1,RAPGEF6,UHRF1BP1L,SRP54,NFASC,IKBIP,PPIP5K2,ADGRL3,ANO4,STON1,EML4,RNF212,CRB1,LINC01551,BAZ1A,RAB2B,RIMBP2,IGSF8,ADAMTS19,ZNF876P,ZNF10,IGF1,KCNT2,ZNF470,ZNF324B,CCDC169,IRF1,LHX9,TTC41P,LETM1" MicroRNA hsa-miR-103-2*:mirSVR_highEffct hsa-miR-103-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.46E-29 2.90E-25 8.91E-28 8.15E-27 77 1437 "KIAA1211,WDR35,SNX24,PPFIA4,MSH2,ARHGAP5,CENPBD1P1,STARD13,NFKBIA,NFXL1,PCSK1,RGSL1,ZNF595,WDFY2,NRXN1,ATAD2B,HOMER1,TAPT1,COPA,FAM53A,GNPTAB,SYCP3,EPGN,CLOCK,NGDN,C12orf65,LRRTM2,UBXN2A,COG3,PTGS2,NUDT12,COCH,G3BP2,RABGAP1L,TSEN15,RNF31,RASA1,TMEM161B,SMC6,SETDB2,PACRGL,MBNL2,FAM81B,CWC27,TRAPPC13,TMEM156,FCAR,NDUFAF7,FGFR3,VEZT,NBEA,SLC8A1,TADA1,CCDC88A,ZNF605,SLC12A2,PKD2L2,C1orf112,MEGF10,PDS5B,ERAP1,SRP72,NEDD1,IKBIP,CFHR4,LPIN1,ANO4,YIPF7,HEXB,TADA2B,IL6ST,ZNF140,LINC00272,LHX9,ZBED3-AS1,FIP1L1,PABPN1" MicroRNA hsa-miR-330-3p:mirSVR_highEffct hsa-miR-330-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.69E-29 3.03E-25 9.26E-28 8.48E-27 88 1871 "NLN,MYBPC1,CAMK4,TAF1B,CAST,RILPL1,FCHO2,PAH,PCDH9,FAM177A1,CDK17,GLT1D1,WDFY2,THAP6,STRN3,TAPT1,GNPTAB,NGDN,CSNK1G3,CEP135,PRKD1,ZFYVE16,SPATA18,DMXL1,FBXL5,OCIAD1,RABGAP1L,WDR1,PARPBP,EGLN3,B3GLCT,RASA1,CLIP4,CRYL1,NTN4,LRPPRC,EIF2D,RNASE2,PACRGL,MBNL2,ELF1,MARVELD2,EFS,SAP18,FCGR3A,UTP15,RELL1,TACC3,SUCO,FOXG1,SELP,FOXO1,FMO1,GFM2,THADA,CCDC88A,N4BP2,YPEL5,NAAA,ERAP1,ATP8A2,HSPH1,ERBIN,GJB2,MAST4,METAP2,GOLGA3,KMT5A,DOCK9,RNF212,TDG,GTF2H3,TNR,KLF12,SLAIN1,POC5,NLRP8,VRK2,KCNT2,ANKS1B,CHPT1,KIF2A,RILPL2,TTC41P,LAD1,RMST,SPRYD7,LIG4" MicroRNA hsa-miR-96:mirSVR_lowEffct hsa-miR-96:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.86E-29 3.11E-25 9.50E-28 8.69E-27 85 1750 "MDM4,BIRC6,SEMA6A,SNX24,RGS5,PPFIA4,APBB2,APC,ASTN1,ATP1A2,STARD13,CBLN3,MORN2,CHAMP1,CD1D,SCARB1,PAH,PCCA,CDK18,PDGFRA,PFKFB2,WDFY2,NRXN1,HEATR5A,CLOCK,SNCAIP,CEP135,PRKD1,ZFYVE16,COG3,CEP350,SACS,PPP2R3C,GALNT14,ATG10,RASA1,RB1,AASDH,CLIP4,LRPPRC,MBNL2,LGR6,MAEA,ETF1,ABCA11P,FCAR,N4BP2L2,RELL1,SUCO,MROH9,DDX51,CCDC92,BRMS1L,CCDC88A,SLC12A2,CGREF1,LIMCH1,DCAF11,CYP1B1-AS1,NPAS3,DRC1,MCCC2,PCDH17,UGT2A1,ADGRL3,ANO4,DOCK9,TDG,FCRLA,RNF17,TEP1,SLC7A8,TMPO,TNR,KLF12,GPN1,STARD4,NSD2,SELENOI,ZBTB41,KIF2A,TTC41P,SLAMF9,AXDND1,LOX" MicroRNA hsa-miR-556-3p:mirSVR_highEffct hsa-miR-556-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.12E-29 3.25E-25 9.89E-28 9.05E-27 67 1080 "SFTA3,BIRC6,MSH2,DDX55,BLZF1,ARL1,ASCL1,SLC4A4,NFATC4,NFKBIA,FCHO2,PAH,PCDH9,SCFD2,CDK17,PDGFRA,CENPC,RCBTB2,GPR180,THAP6,CRHBP,CSNK1G3,UBXN2A,ZNF586,ZFYVE16,MATR3,COG3,G3BP2,DHFR,C14orf119,NR1I3,RASA1,TMEM161B,ZNF329,DTD2,PACRGL,MBNL2,ARSK,GMPR2,TLR6,USP44,FCGR3A,FCGR3B,GORAB,TNFRSF19,FGFR3,POLK,SUCO,FOXO1,VEZT,PKD2L2,C1orf112,MRPS27,IKBIP,PPARGC1A,METAP2,ADGRL3,EML4,SNRNP35,TFDP1,MSH6,AP4S1,TNR,TECRL,GUF1,TENT2,SPRYD7" MicroRNA hsa-miR-1255b:mirSVR_lowEffct hsa-miR-1255b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.84E-29 4.17E-25 1.26E-27 1.15E-26 82 1638 "MAP1B,MATN3,DHX37,PPFIA4,APAF1,BLZF1,WDR19,FAM193A,AACS,NCOA1,ATP2B4,CD84,ARHGEF7,LINC02347,CACNA1E,TAF1B,CD1D,UHMK1,PCDH9,PDGFRA,PFKFB2,CHIT1,ZNF595,POLN,PTPRVP,C1orf116,THTPA,LYSMD3,NGDN,DNM3,CMTM5,SPATA18,PIGG,CEP350,OCIAD1,PARPBP,C14orf119,RB1,OGFOD2,POLR1D,PACRGL,EFNA5,RNF4,MBNL2,DCUN1D2,FCAMR,STX2,FAM172A,ADGRV1,GMPR2,TOMM40L,SPON2,FTLP10,ZCCHC8,RUBCNL,SLC34A2,NBEA,SLC12A2,SLC15A4,C1orf112,SLC22A4,UGGT2,PDS5B,LRCH1,LILRB1,PPARGC1A,TBC1D1,C5orf56,DOCK9,RNF212,FCRLA,CRB1,TMPO,ZNF876P,NSD2,C12orf73,GALP,KIR2DS4,LAD1,LINC01913,SPRYD7,MICU2" MicroRNA hsa-miR-376b:mirSVR_lowEffct hsa-miR-376b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.84E-29 4.17E-25 1.26E-27 1.15E-26 82 1638 "SFTA3,MAP1B,BIRC6,NLN,PITPNM2,WDR19,ARHGAP5,ARL1,ASTN1,CENPBD1P1,SLC4A4,KCTD12,CACNA1E,MPZL1,PAH,DCLK1,XPR1,PIK3C2B,HECTD1,STRN3,MPC2,COPA,EPGN,PREPL,CMTM5,FCRL2,DCAF8,LOC439933,NUDT12,PARPBP,RNF219,RASA1,RGS12,LRPPRC,RNASEL,GRTP1,UGT2A3,ELF1,TCTN2,ETF1,F7,USP44,FCGR2B,FNIP1,PIBF1,SUCO,FOXG1,FLT1,FLT3,SFSWAP,BRMS1L,SLC30A6,C1orf112,ACIN1,MEGF10,TMEM183A,UHRF1BP1L,IQGAP2,ATP8A2,NEDD1,PCDH17,PPARGC1A,GJA3,INSM2,SCFD1,GPR12,C1QTNF9B,TGFBI,AP4S1,GTF3C2,BAZ1A,MAEL,NPL,GPN1,SELENOI,C12orf73,IL6ST,CHPT1,AMTN,LAD1,RMST,AXDND1" MicroRNA hsa-let-7c*:mirSVR_lowEffct hsa-let-7c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.21E-29 4.37E-25 1.32E-27 1.20E-26 80 1561 "ANKRD34B,PITPNM2,MCFD2,APAF1,CENPBD1P1,CCNB1IP1,ATP12A,SLC4A4,ADGRD1,DAOA,TAF1B,CAST,NFXL1,PCDH9,FAM177A1,CDK17,PDE4D,CENPC,PFKFB2,VIT,ITGBL1,TM9SF2,NRXN1,THAP6,STRN3,GNPTAB,TOGARAM2,THTPA,LACC1,TTC37,DNM3,ZNF586,ZFYVE16,CEP350,NUDT12,RABGAP1L,GNPDA2,SUPT7L,RB1,TMEM33,CLIP4,LRPPRC,EIF2D,EIF2B1,KIRREL1,CWC27,DLEU1,ABCA11P,GMPR2,TRAPPC13,GORAB,PIBF1,SUCO,HSD17B7,FBXO11,LIMCH1,GABRA2,GABRB1,PDS5B,NMNAT2,TMEM183A,KDM3B,GPR12,KHNYN,CRB1,MAEL,ZNF721,ATP6V0A2,TPO,TECRL,RXFP2,TENT2,WDR36,YTHDC2,ZMYM2,ZBTB41,CHPT1,KCNN2,AXDND1,PABPN1" MicroRNA hsa-miR-32:mirSVR_highEffct hsa-miR-32:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.74E-29 4.65E-25 1.40E-27 1.28E-26 69 1156 "MAP1B,KIAA1211,PITPNM2,CDKL4,BLZF1,NCOA1,ATP2B4,STARD13,ARHGEF7,NOVA1,FCHO2,LDB2,CD1D,PDE4D,ZNF595,PGGT1B,GPR180,NUP37,JAKMIP1,HECTD1,THAP6,STRN3,CRHBP,C12orf65,ZNF586,COG3,DMXL1,G3BP2,FAM129A,AASDH,LAP3,LATS2,RNF4,ABCA11P,USP44,FNIP1,FGF9,POLK,SUPT20H,ZCCHC8,RUBCNL,BRMS1L,ALKAL2,UFM1,ZNF605,SLC12A2,SLC22A4,LIMCH1,PDS5B,NAAA,IQGAP2,NPAS3,RBKS,LRCH1,ZNF544,GOLGA3,ANO4,DOCK9,FZD10,ZNF721,TRPC4,TENT2,ZNF26,KCNT2,DIAPH3,KIT,RMST,AXDND1,LMNB1" MicroRNA hsa-miR-582-3p:mirSVR_highEffct hsa-miR-582-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.47E-29 5.03E-25 1.51E-27 1.38E-26 64 987 "EP400,ARHGAP5,ASCL1,ARHGEF7,CCNA1,CAMK4,PCCA,ZMYM5,CDK7,PGGT1B,GPR180,MRPL57,TM9SF2,ATAD2B,BOD1L1,ADGRF3,GNPTAB,PM20D1,LYSMD3,CSNK1G3,CEP135,FAM169A,UBXN2A,FCRL2,ZFYVE16,SPATA18,CEP350,TBC1D4,CEP120,SACS,PARPBP,TSEN15,RAN,CLIP4,GUSBP3,PACRGL,TRIM28,ELK3,MARVELD2,DRAM1,DNAJC27,CLIP1,TNFRSF19,MROH9,FMO1,NBEA,MBIP,SCYL2,TADA1,WDCP,YPEL5,GABRA2,NMNAT2,UHRF1BP1L,SRP72,MCCC2,IKBIP,PCDH17,ATP6V0A2,HMGCR,NSD2,KCNT2,KIF2A,SKA3" MicroRNA hsa-miR-152:mirSVR_highEffct hsa-miR-152:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.55E-29 5.08E-25 1.52E-27 1.39E-26 70 1193 "MAP1B,MATN3,TMEM132B,PITPNM2,WDR19,NCOA1,ATP1A2,ATP4B,STARD13,LINC02347,DAOA,CAST,LDB2,PAH,PCCA,WDR66,CEBPE,CFL2,CHD1,PFKFB2,GPR180,JAKMIP1,THAP6,HOMER1,AKAP6,LYSMD3,CLOCK,ITSN2,MATR3,DMXL1,NUDT12,SACS,PARPBP,PPP2R3C,RNF219,NR1H4,CLIP4,RNASEL,ARSK,F10,NDUFAF7,FGF9,PIBF1,SUCO,SDC1,FLT1,FBXO11,GABRA2,KDM5B,TMEM183A,ZNF274,LRCH1,IKBIP,PPARGC1A,INSM2,ATP11A,TGM1,LINC01551,ADAMTS19,TENT2,YTHDC2,FCRL6,FAM49A,CHPT1,KCNN2,KIT,SPRYD7,AXDND1,LIG4,LMNB1" MicroRNA hsa-miR-3182:mirSVR_highEffct hsa-miR-3182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.60E-29 5.10E-25 1.52E-27 1.39E-26 73 1301 "ABL2,MAP1B,MDM4,EP400,FBRSL1,APC,MSH2,DDX55,FAM193A,DAOA,CAST,LDB2,PCK2,CDK18,RGSL1,PDGFRA,CHD1,GPR180,ITGBL1,JAKMIP1,THAP6,GNPTAB,TOGARAM2,THTPA,EPGN,NGDN,CEP135,UBXN2A,PRKD1,DCAF8,MATR3,COG3,LOC439933,COCH,TINF2,DHFR,PARPBP,CLIP4,MARVELD2,TBC1D19,DLEU1,GORAB,PIBF1,SUCO,SUPT20H,VEZT,FBXO11,IVNS1ABP,PKD2L2,POTEM,C1orf112,NMNAT2,JPH4,RAPGEF6,MCCC2,LPIN1,STRN,BRD8,INSM2,LINC02393,SCFD1,LILRB4,EML4,AP4S1,RASSF6,HEXB,ZNF876P,KCNT2,RILPL2,ZDHHC20,CDK2AP1,PABPN1,LOX" MicroRNA hsa-miR-33a:mirSVR_highEffct hsa-miR-33a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.12E-28 5.96E-25 1.77E-27 1.62E-26 64 990 "MATN3,ATP6V1G3,MSH2,BLZF1,STXBP6,ASCL1,KCTD12,NFATC4,CAMK4,FCHO2,LDB2,SNTG2,PDE4D,CHD1,LINC01085,THAP6,HOMER1,AKAP6,VCAN,DNM3,PRKD1,ZFYVE16,SPATA18,SREK1,LOC439933,PTPRC,GNPDA2,NR1I3,EGLN3,FAM129A,RASA1,SMC6,AASDH,LAP3,RGS12,TMEM33,NTN4,GUSBP3,PACRGL,ARSK,DLEU1,TRAPPC13,PIBF1,FMO1,SLC12A2,FSHR,YPEL5,NAAA,ERAP1,STRN,PSME4,ZNF544,LINC02393,PPIP5K2,STON1,CRB1,LINC01551,ADAMTS19,HMGCR,ZNF140,KIF3C,RMST,AXDND1,LIG4" MicroRNA hsa-miR-374b*:mirSVR_highEffct hsa-miR-374b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-28 6.67E-25 1.97E-27 1.81E-26 64 992 "MATN3,CUL4A,SNX24,APC,KCTD12,ADGRD1,CACNA1E,CAST,CHAMP1,CDK17,PFKFB2,CFAP45,HECTD1,RCHY1,TOGARAM2,IL20,ITSN2,FAM169A,FCRL5,ZNF586,SREK1,CEP350,PTPRC,TINF2,PARPBP,RAN,AASDH,RNASEL,UGT2A3,TBC1D19,FAM172A,MAEA,ELOVL7,UTP15,FGF9,POLK,PEAR1,FOXO1,FLT1,UFM1,THADA,CCDC88A,SLC12A2,GABRA2,RAPGEF6,NPAS3,LRCH1,PCDH17,MIMT1,PPARGC1A,ADGRL3,ADGRA3,ACSL6,EML4,GUF1,TMEM174,TENT2,C12orf73,CHPT1,KCNN2,CAB39L,KIF2A,RMST,TTC7A" MicroRNA hsa-miR-200c:mirSVR_highEffct hsa-miR-200c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.35E-28 7.19E-25 2.12E-27 1.94E-26 86 1812 "RALGAPA1,ABL2,COG6,CUL4A,MCFD2,DDX55,BLZF1,WDR19,ARL1,STARD13,NFATC4,NOVA1,CAST,CHAMP1,CDK17,CFL2,CHD1,PFKFB2,WDFY2,NRXN1,ATAD2B,COPA,GNPTAB,LYSMD3,LACC1,CSNK1G3,FAM169A,FCRL5,ZNF586,DCAF8,MATR3,CEP350,OCIAD1,SUPT7L,PARPBP,TSEN15,DNMT3A,EGLN3,B3GLCT,ARGLU1,LRPPRC,RNASEL,DLEU1,CLIP1,TRAPPC13,FGF9,RELL1,POLK,FOXG1,MROH9,FOXO1,SUPT20H,VEZT,G2E3,BRMS1L,MBIP,UFM1,THADA,SLC12A2,NR5A2,ZNF667,KIF21B,ZNF274,MRPS27,NEDD1,IKBIP,COMMD6,MAST4,PSME4,INSM2,METAP2,ADGRL3,C5orf56,BAZ1A,ATP6V0A2,SLAIN1,VRK2,SPTSSA,LHX9,CHPT1,TMEM178A,KIF2A,TTC41P,RMST,IFT88,LOX" MicroRNA hsa-miR-921:mirSVR_lowEffct hsa-miR-921:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-28 7.29E-25 2.14E-27 1.96E-26 76 1420 "MCC,SNX24,MCFD2,BLZF1,ATP1A2,ZNF542P,CD84,ARHGEF7,ADGRD1,DAOA,CAST,SNTG2,DCLK1,PIWIL1,GPR180,NRXN1,THAP6,PREPL,SNCAIP,EIF2AK2,COCH,RABGAP1L,PARPBP,NR1I3,ARGLU1,MEMO1,RNASEL,LATS2,ELK3,DHRS2,TBC1D19,CWC27,ABCA11P,PCBD2,IRF9,FNIP1,PIBF1,POLK,FOXG1,FLT3,ZCCHC8,NBEA,BRMS1L,THADA,C1orf112,YPEL5,SNRPF,KDM5B,CMPK2,RBKS,UGT2A1,INSM2,ARHGEF28,EML4,DOCK9,KHNYN,FCRLA,RIMBP2,MAEL,ADAMTS19,TECRL,GUF1,PAPPA2,WDR36,KCNT2,MZF1,SPTSSA,ZMYM2,IRF1,ZBTB41,SDR39U1,NPHS2,KIF2A,EP400P1,LETM1,AXDND1" MicroRNA hsa-miR-488:mirSVR_highEffct hsa-miR-488:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.48E-28 7.86E-25 2.30E-27 2.11E-26 74 1347 "COG6,MCFD2,CDKL4,BLZF1,AACS,SLC4A4,KCTD12,ARHGEF7,CDKL2,NFXL1,PCCA,PCDH9,CENPC,RCHY1,PREPL,CRHBP,NGDN,LACC1,PRKD1,BIVM,SREK1,PTGS2,FBXL5,CEP350,KLHL3,GNPDA2,SUPT7L,PARPBP,RNF31,RASA1,ARGLU1,SLC9C2,RGS4,TMEM33,CLIP4,POLR1D,STK32B,ETF1,DLEU1,PCGF3,GORAB,FGF9,FGFR3,TACC3,UFM1,C1orf112,MYO16,GABRA2,MYT1L,GABRB1,PDS5B,RAPGEF6,NPAS3,KDM3B,NEDD1,ERBIN,ZBTB37,LPIN1,PPARGC1A,STRN,MAST4,ANO4,STON1,CRB1,UBC,IGF1,SPTSSA,ANKS1B,IRF1,CAB39L,KIR2DS4,RMST,LMNB1,LOX" MicroRNA hsa-miR-4280:mirSVR_lowEffct hsa-miR-4280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-28 8.23E-25 2.41E-27 2.20E-26 74 1348 "MCC,BIRC6,ANKRD34B,MIPEP,APBB2,APC,BLZF1,CACNA1E,RILPL1,CDK7,PCSK1,CDK17,CCDC122,CPNE6,HEATR5A,VCAN,DNM3,FCRL5,ZNF586,B3GLCT,SMC6,SLC9C2,UGT2A3,ELF1,MPHOSPH9,DLEU1,ABCA11P,TRAPPC13,PCBD2,TOMM40L,GORAB,FNIP1,N4BP2L2,PIBF1,SELP,FOXO1,FTLP10,SUPT20H,FBXO11,G2E3,MBIP,IVNS1ABP,EFR3B,CYP1B1-AS1,MYT1L,GABRB1,PDS5B,NMNAT2,PPARGC1A,ZNF544,ATP11A,ADAM17,METAP2,MTUS2,ANO4,GPR12,RIPK3,DOCK9,BAZ1A,GZMH,ZNF721,ADAMTS19,UBE2K,TECRL,SLAIN1,WDR36,NSD2,ZNF84,ZBED3-AS1,KIF2A,KIF3C,SPRYD7,AXDND1,LOX" MicroRNA hsa-miR-3136:mirSVR_lowEffct hsa-miR-3136:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-28 8.33E-25 2.43E-27 2.22E-26 82 1655 "MCC,ADD1,KIAA1211,EP400,PPFIA4,UVSSA,MSH2,ARL1,SLC4A4,ARHGEF7,LINC02347,MPZL1,CAST,LDB2,SCARB1,FCRLB,DCLK1,MRPL57,COPA,EPGN,LYSMD3,SNCAIP,CEP135,PRKD1,FCRL5,MATR3,PIGG,DMXL1,F11R,SLC35F6,LINC01257,PPP2R3C,DNMT3A,RAN,B3GLCT,DTD2,CLIP4,EIF2D,EFNA5,MPHOSPH9,TBC1D19,USP44,NDUFAF7,SULT6B1,TNFRSF19,G2E3,NBEA,UFM1,SLC8A1,THADA,P2RX2,WDCP,C1orf112,ZNF667,MYO16,MEGF10,UHRF1BP1L,ATP8A2,HSPH1,NFASC,SRP72,GJA3,TMED2,MTUS2,ADGRL3,ARHGEF28,TEP1,TFDP1,RIMBP2,MAEL,HEXB,ADAMTS19,ZNF550,WDR36,TDRD3,CAB39L,KIF3C,KIR3DL2,TTC41P,MFSD2B,LINC01913,LOX" MicroRNA hsa-miR-516b*:mirSVR_lowEffct hsa-miR-516b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-28 8.47E-25 2.46E-27 2.25E-26 89 1940 "TMEM132B,ACOX3,SLAMF6,COG6,RGS5,MSH2,ARL1,CENPBD1P1,B4GALT3,KCTD12,MYH7,NFATC4,CAMK4,RILPL1,UHMK1,PCDH9,ZMYM5,GLT1D1,PDE6B,SLC25A3,PIK3C2B,LTB4R,ITSN2,LRRTM2,KIAA0040,UBXN2A,FCRL5,DCAF8,COG3,KLHL3,TINF2,PPP2R3C,B3GLCT,RASA1,CLIP4,MEMO1,POLR1D,LRPPRC,PACRGL,MAEA,ETF1,FCAR,TOMM40L,FNIP1,TACC3,SUCO,MROH9,FLT1,FTLP10,RUBCNL,UFM1,SLC8A1,ARHGEF40,SLC12A2,POTEM,CGREF1,WDCP,SLC22A4,PDS5B,KDM5B,TMEM183A,IKBIP,GJA3,TBC1D1,METAP2,TCF7,ARHGEF28,EML4,KMT5A,DOCK9,GRSF1,MSH6,ACTR6,ADAMTS19,HMGCR,VRK2,MZF1,JCHAIN,TADA2B,ZNF84,SELENOI,IL6ST,PLB1,TDRD3,LMLN,FIP1L1,LINC01913,IFT88,MICU2" MicroRNA hsa-miR-516a-3p:mirSVR_lowEffct hsa-miR-516a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-28 8.47E-25 2.46E-27 2.25E-26 89 1940 "TMEM132B,ACOX3,SLAMF6,COG6,RGS5,MSH2,ARL1,CENPBD1P1,B4GALT3,KCTD12,MYH7,NFATC4,CAMK4,RILPL1,UHMK1,PCDH9,ZMYM5,GLT1D1,PDE6B,SLC25A3,PIK3C2B,LTB4R,ITSN2,LRRTM2,KIAA0040,UBXN2A,FCRL5,DCAF8,COG3,KLHL3,TINF2,PPP2R3C,B3GLCT,RASA1,CLIP4,MEMO1,POLR1D,LRPPRC,PACRGL,MAEA,ETF1,FCAR,TOMM40L,FNIP1,TACC3,SUCO,MROH9,FLT1,FTLP10,RUBCNL,UFM1,SLC8A1,ARHGEF40,SLC12A2,POTEM,CGREF1,WDCP,SLC22A4,PDS5B,KDM5B,TMEM183A,IKBIP,GJA3,TBC1D1,METAP2,TCF7,ARHGEF28,EML4,KMT5A,DOCK9,GRSF1,MSH6,ACTR6,ADAMTS19,HMGCR,VRK2,MZF1,JCHAIN,TADA2B,ZNF84,SELENOI,IL6ST,PLB1,TDRD3,LMLN,FIP1L1,LINC01913,IFT88,MICU2" MicroRNA hsa-miR-147:mirSVR_lowEffct hsa-miR-147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-28 8.72E-25 2.52E-27 2.31E-26 84 1736 "ASTN1,CENPBD1P1,ATP1A2,BCL2L2,CD84,NFATC4,CD1E,PCCA,PCDH9,CDK18,PDE4D,PDE6B,ZNF595,SLC25A3,ADGRF3,C1orf116,POLE,TOGARAM2,CLOCK,LRRTM2,FAM169A,UBXN2A,FCRL5,GLT8D2,IFT172,SPATA18,PTPRC,DHFR,PARPBP,ATG10,ZNF329,FAM228A,LAP3,NTN4,GUSBP3,PACRGL,EFNA5,MBNL2,KIRREL1,MPHOSPH9,FAM172A,ABCA11P,PCGF3,F10,FCAR,TOMM40L,NDUFAF7,FOXG1,HSD17B7,DDX51,CCDC92,NUBPL,PAICS,ARHGEF40,CCDC88A,POTEM,C1orf112,PDS5B,NFASC,DRC1,KLHL20,PCDH17,LPIN1,ATP11A,METAP2,C5orf56,ARHGEF28,STON1,DOCK9,RNF212,NCSTN,TEP1,CRB1,LINC01551,TNNT2,ARHGAP30,TXK,NSD2,CCDC169,LHX9,TDRD3,KCNN2,RILPL2,SPATA13" MicroRNA hsa-miR-519e*:mirSVR_highEffct hsa-miR-519e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-28 9.87E-25 2.84E-27 2.60E-26 78 1503 "COG6,SNX24,APAF1,MSH2,ARL1,ASCL1,NCOA1,ATP1A2,SLC4A4,ZNF542P,CD84,ARHGEF7,NFKBIA,PNP,CAST,PCCA,CDK7,PDGFRA,GLT1D1,PIWIL1,ZNF595,PGGT1B,TSTD1,ITGBL1,ADGRF3,AKAP6,POU2F1,C12orf65,LRRTM2,DNM3,UBXN2A,FCRL5,NOS1AP,IFT172,MATR3,OCIAD1,SACS,G3BP2,RABGAP1L,GNPDA2,NTN4,RNF4,EIF2B1,BORA,SAP18,ETF1,ABCA11P,ADGRV1,PCBD2,GORAB,FNIP1,SELP,FBXO11,GFM2,ARHGEF40,N4BP2,GABRB1,HSPH1,KDM3B,DRC1,RBKS,NEDD1,IKBIP,LPIN1,PPARGC1A,RNF212,RNF17,LINC01551,AP4S1,MAEL,ZNF721,RXFP2,ZNF140,KIF2A,DNAH10,AXDND1,LMNB1,SKA3" MicroRNA hsa-miR-4263:mirSVR_highEffct hsa-miR-4263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-28 1.13E-24 3.24E-27 2.97E-26 71 1245 "SMIM15,KIAA1211,ANKRD34B,NCOA1,RAB29,TAF1B,FCGR2C,FCRLB,PDE4D,CFL2,NRXN1,LTB4R,THAP6,HOMER1,SNCAIP,CSNK1G3,CEP135,FAM169A,MPHOSPH8,PRKD1,ZFYVE16,COCH,PTPRC,SUPT7L,LINC01257,TSEN15,NR1H4,GALNT14,RB1,AASDH,SLC9C2,CLIP4,SETDB2,LATS2,ELK3,MARVELD2,FAM172A,DLEU1,ABCA11P,ADGRV1,SH3YL1,TRAPPC13,VEZT,NBEA,PAICS,THADA,CCDC88A,LIMCH1,RAPGEF6,EAPP,HSPH1,SRP72,IKBIP,PPARGC1A,UTP20,ADAM17,COX18,LINC01551,TMPO,HEXB,GUF1,HSD17B4,VRK2,STARD4,NSD2,KCNT2,ZNF470,CHPT1,LMLN,AMTN,SPATA13" MicroRNA hsa-miR-486-5p:mirSVR_lowEffct hsa-miR-486-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-28 1.13E-24 3.25E-27 2.97E-26 74 1355 "ATP6V1G3,COG6,SNX24,APC,BLZF1,FAM193A,AACS,NCOA1,SLC5A6,AP1G2,CAST,FCHO2,FCGR2C,PCSK1,ZNF595,ITGBL1,THAP6,AKAP6,POU2F1,EPGN,LYSMD3,NCOR2,BRI3BP,CSNK1G3,ITSN2,UBXN2A,SNX17,COG3,CEP350,G3BP2,C14orf119,NR1I3,TMEM33,PACRGL,LATS2,ARSK,ETF1,TRAPPC13,POLK,SUCO,SDC1,FBXO11,ALKAL2,NUBPL,UFM1,SLC8A1,THADA,CCDC88A,C1orf112,LIMCH1,GABRA2,KDM5B,TMEM183A,ZNF274,OXGR1,NEDD1,BRD8,MAST4,TMED2,ADGRL3,ANO4,ACSL6,STON1,EML4,KMT5C,DOCK9,CRB1,TMPO,RIMBP2,UBE2K,FCRL6,RNASE11,SPRYD7,ZNF304" MicroRNA hsa-miR-155*:mirSVR_lowEffct hsa-miR-155*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-28 1.14E-24 3.25E-27 2.97E-26 76 1430 "MAP1B,MATN3,MCC,SLAMF6,TBC1D14,RGS5,MCFD2,APBB2,KCTD12,MYH6,NFKBIA,NOVA1,PAH,ZMYM5,PDE4D,PDGFRA,WDFY2,MRPL57,NRXN1,PIK3C2B,POU2F1,LRRTM2,DNM3,NOS1AP,ZFYVE16,LOC439933,TBC1D4,OCIAD1,TINF2,NR1H4,TMEM161B,CLIP4,RNASEL,TCTN2,STX2,DRAM1,CWC27,MAEA,FCGR3B,POLK,FBXO11,DDX51,BRMS1L,NUBPL,SCYL2,IVNS1ABP,SLC12A2,N4BP2,DCAF11,GABRB1,RAPGEF6,TMEM183A,ERAP1,LILRB1,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ARHGEF28,TDG,GRSF1,ZBTB49,LINC01551,TMPO,KLF12,UBE2K,TMEM174,POC5,NSD2,YTHDC2,ZNF10,ZNF84,CCDC190,ZBTB41,RMST" MicroRNA hsa-miR-4306:mirSVR_highEffct hsa-miR-4306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-28 1.15E-24 3.29E-27 3.01E-26 69 1174 "MDM4,SLAMF6,NYNRIN,B4GALT3,CADM3,FCRL3,DAOA,RILPL1,LDB2,CD1D,CD1E,RFLNA,PCCA,PCDH9,PDE6B,CKMT2,CPNE6,AKAP6,RNASE9,GNPTAB,PM20D1,PREPL,CSNK1G3,UBXN2A,FCRL5,ZNF586,DCAF8,KLHL3,COCH,PARPBP,NR1I3,FAM129A,CRYL1,RNASE2,FAM172A,ABCA11P,TRAPPC13,POLK,SLC30A6,SLC8A1,TADA1,WDCP,PDS5B,KDM3B,SRP72,GCKR,LILRB1,BRD8,MAST4,PSME4,COP1,NCSTN,TFDP1,GZMH,RAB2B,MAEL,TNR,NPL,HEXB,TPO,PLB1,FAM151B,NPHS2,KCNN2,KIF3C,KIR2DL4,KIR3DL2,AXDND1,IFT88" MicroRNA hsa-miR-337-3p:mirSVR_lowEffct hsa-miR-337-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.22E-28 1.18E-24 3.36E-27 3.08E-26 71 1246 "MAP1B,IL17D,KIAA1211,COG6,UVSSA,APBB2,ASCL1,CD84,CENPC,PFKFB2,CCDC122,CHIT1,PIK3C2B,ATAD2B,STRN3,COPA,CRHBP,NGDN,CEP135,DNM3,KIAA0040,SNX17,SPATA18,NUDT12,CEP120,TINF2,ATG10,RGS12,TMEM33,POLR1D,GUSBP3,LATS2,ARSK,SAP18,DLEU1,ABCA11P,FCAR,GORAB,FNIP1,FGF9,FOXG1,SLC8A1,THADA,YPEL5,CMPK2,ERBIN,IKBIP,ZNF544,TBC1D1,ACSL6,RIPK3,DOCK9,FCRLA,ZBTB49,ADAMTS19,TECRL,GUF1,TMEM174,WDR36,STARD4,DCP2,IGF1,ZNF84,ANKS1B,KCNJ9,LMLN,TTC41P,LINC01913,RMST,LMNB1,ZNF304" MicroRNA hsa-miR-518a-5p:mirSVR_highEffct hsa-miR-518a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.45E-28 1.30E-24 3.68E-27 3.37E-26 73 1321 "ABL2,SMIM15,ULK1,ASCL1,ATP1A2,STARD13,BTF3,NOVA1,PNP,FCHO2,PDGFRA,NRXN1,JAKMIP1,CLOCK,IL20,PRKD1,SPATA18,COG3,FBXL5,CEP350,TBC1D4,OCIAD1,RABGAP1L,OGFOD2,AASDH,CLIP4,MEMO1,EIF2D,RNASE2,TXNDC15,LATS2,MBNL2,MPHOSPH9,TBC1D19,STK32B,ETF1,CLIP1,F7,SLC22A17,F10,TRAPPC13,TOMM40L,GORAB,PIBF1,NBEA,MBIP,SLC30A6,IVNS1ABP,TADA1,LIMCH1,NAAA,OXGR1,CMPK2,RBKS,NPFFR2,LPIN1,PPARGC1A,MAST4,TMED2,PPIP5K2,GPR12,TEP1,TMPO,FZD10,HAL,TUBA3C,ZNF470,PLB1,ZMYM2,ZBED3-AS1,KIT,AXDND1,PABPN1" MicroRNA hsa-miR-527:mirSVR_highEffct hsa-miR-527:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.45E-28 1.30E-24 3.68E-27 3.37E-26 73 1321 "ABL2,SMIM15,ULK1,ASCL1,ATP1A2,STARD13,BTF3,NOVA1,PNP,FCHO2,PDGFRA,NRXN1,JAKMIP1,CLOCK,IL20,PRKD1,SPATA18,COG3,FBXL5,CEP350,TBC1D4,OCIAD1,RABGAP1L,OGFOD2,AASDH,CLIP4,MEMO1,EIF2D,RNASE2,TXNDC15,LATS2,MBNL2,MPHOSPH9,TBC1D19,STK32B,ETF1,CLIP1,F7,SLC22A17,F10,TRAPPC13,TOMM40L,GORAB,PIBF1,NBEA,MBIP,SLC30A6,IVNS1ABP,TADA1,LIMCH1,NAAA,OXGR1,CMPK2,RBKS,NPFFR2,LPIN1,PPARGC1A,MAST4,TMED2,PPIP5K2,GPR12,TEP1,TMPO,FZD10,HAL,TUBA3C,ZNF470,PLB1,ZMYM2,ZBED3-AS1,KIT,AXDND1,PABPN1" MicroRNA hsa-miR-145:mirSVR_highEffct hsa-miR-145:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.52E-28 1.34E-24 3.77E-27 3.45E-26 75 1396 "RALGAPA1,ABL2,ACOX3,NLN,MIPEP,SEMA6A,SNX24,APAF1,MSH2,SLC5A6,CAST,CD1D,ZMYM5,GLT1D1,CFL2,PGGT1B,WDFY2,GPR180,COLEC11,JAKMIP1,THAP6,TAPT1,EPGN,CRHBP,ITSN2,UBXN2A,DMXL1,F11R,B3GLCT,RASA1,SMC6,SLC9C2,NTN4,PACRGL,SAP18,ADGRV1,CLIP1,F10,PCBD2,NDUFAF7,GORAB,FGFR3,PIBF1,FOXO1,FLT1,FLT3,HSD17B7,UFM1,IVNS1ABP,CHFR,MEGF10,GABRB1,EAPP,GC,MCCC2,ERBIN,LILRB1,ZNF544,TMED2,ATP11A,ADAM17,PPIP5K2,METAP2,DOCK9,RNF17,SLC7A8,TENT2,ITLN2,KCNT2,CHPT1,TMEM178A,FIP1L1,RNASE11,PABPN1,LOX" MicroRNA hsa-miR-4309:mirSVR_lowEffct hsa-miR-4309:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.87E-28 1.52E-24 4.28E-27 3.92E-26 80 1591 "MCC,MDM4,SLAMF6,NYNRIN,MCFD2,MSH2,ARHGAP5,FAM193A,ATP1A2,SLC4A4,NOVA1,CAD,CDKL2,FCGR2C,PAH,FAM177A1,XPR1,CCDC122,WDFY2,THAP6,AKAP6,FAM163A,COPA,RCHY1,PREPL,IL20,TTC37,FAM169A,FCRL5,BIVM,PSME1,GNPDA2,LINC01257,PARPBP,B3GLCT,ZNF329,TMEM33,SETDB2,LRPPRC,EFNA5,TXNDC15,DRAM1,ADGRV1,F7,FCAR,TNFRSF19,POLK,FTLP10,SUPT20H,VEZT,G2E3,PAICS,SLC30A6,ARHGEF40,NMNAT2,ZNF274,OXGR1,CMPK2,NFASC,LRCH1,LILRB1,LPIN1,ACSL6,GPR12,STON1,KMT5C,RNF212,TDG,COX18,RNF17,HEXB,TPO,MZF1,TADA2B,ZBED3-AS1,CHPT1,ANKDD1B,EP400P1,TTC41P,NUAK2" MicroRNA hsa-miR-770-5p:mirSVR_lowEffct hsa-miR-770-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-28 1.62E-24 4.52E-27 4.14E-26 76 1438 "RALGAPA1,MATN3,MDM4,BIRC6,COG6,MSH2,ARHGAP5,B4GALT3,PPP1R12B,NOVA1,DAOA,CDKL2,CAST,FCHO2,FCGR2C,SCARB1,UHMK1,PCK2,CDK17,CCDC122,CFAP54,PIGR,LACC1,BIVM,EPS8L1,PTGS2,CEP350,NUDT12,G3BP2,RABGAP1L,RNF219,DNMT3A,GALNT14,ATG10,DTD2,SETDB2,MBNL2,SPATA9,GP6,ETF1,TOMM40L,NDUFAF7,SUCO,FLT1,RASA3,TADA1,ZNF605,SLC15A4,CYP1B1-AS1,MYO16,PDS5B,ZNF274,HSPH1,MCCC2,NEDD1,LRCH1,ERBIN,NMU,GJA3,SPIC,ANO4,TCF7,NT5C1B,TFDP1,CRB1,RIMBP2,GPN1,NSD2,FCRL6,ZNF470,FAM151B,CHPT1,KCNN2,RNASE11,NUAK2,AXDND1" MicroRNA hsa-miR-24:mirSVR_lowEffct hsa-miR-24:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-28 1.63E-24 4.55E-27 4.17E-26 90 2000 "RALGAPA1,TMEM132B,ACOX3,ADORA1,NYNRIN,MCFD2,PPFIA4,APBB2,AACS,NCOA1,ATP4B,CADM3,BCL2L2,NFATC4,SLC5A6,LINC02347,RAB29,FCHO2,FCGR2C,SCARB1,UHMK1,FCRLB,RFLNA,PCCA,PCDH9,CDK17,CDK18,RGSL1,GLT1D1,VIT,WDFY2,NRXN1,PIGR,PTPRVP,THAP6,POLE,GALNT9,C12orf65,DNM3,FCRL5,EPS8L1,CEP120,OCIAD1,RABGAP1L,SLC35F6,RNF31,ZNF329,ELK3,MARVELD2,DHRS2,TBC1D19,ABCA11P,FCGR3B,TNFRSF19,POLK,FBXO11,NUBPL,TMEM132D,ZNF667,KIF21B,KDM5B,NAAA,NFASC,GC,ANKLE2,BRD8,MTUS2,TCF7,RIPK3,ARHGEF28,KMT5A,KMT5C,XPO4,NCSTN,ATP6V0A2,NPL,ADAMTS19,UBE2K,HPCAL1,JCHAIN,ZNF84,PLB1,IRF1,PGAM5,SDR39U1,KCNN2,KIF3C,KIR2DL4,KIR2DS4,NUAK2" MicroRNA hsa-miR-1322:mirSVR_lowEffct hsa-miR-1322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.16E-28 1.68E-24 4.67E-27 4.28E-26 77 1477 "RALGAPA1,TMEM132B,APC,FAM193A,KCTD12,ATP7B,ADGRD1,CD1E,CDK17,TSTD1,PTPRVP,THAP6,PMCH,AKAP6,STRN3,TAPT1,CMTM5,FCRL2,GLT8D2,ZFYVE16,BIVM,KLHL3,OCIAD1,G3BP2,RABGAP1L,FAM129A,ATG10,TMEM33,CLIP4,MEMO1,MPHOSPH9,TBC1D19,PCGF3,ARL6IP4,FNIP1,FOXO1,FTLP10,FBXO11,NBEA,BRMS1L,THADA,ZNF605,SLC12A2,POTEM,CGREF1,SLC22A4,YPEL5,KDM5B,TMEM183A,OXGR1,SRP54,NFASC,ZBTB37,STRN,PPIP5K2,ADGRA3,ANO4,ARHGEF28,DOCK9,GPR161,AP4S1,HEXB,UBE2K,ZNF876P,TENT2,NSD2,ZNF84,ZNF324B,C12orf73,ZMYM2,LHX9,CHPT1,KCNN2,ANKDD1B,KIR2DL4,SPRYD7,SKA3" MicroRNA hsa-miR-1910:mirSVR_lowEffct hsa-miR-1910:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.24E-28 1.72E-24 4.78E-27 4.38E-26 86 1835 "ABL2,MDM4,NLN,CENPBD1P1,PPP1R12B,CD84,BTF3,SLC5A6,CCNA1,LINC02347,NOVA1,CDKL2,PCCA,PCK2,SCFD2,GLT1D1,PFKFB2,SLC25A3,POU2F1,FAM169A,UBXN2A,NOS1AP,IFT172,PTGS2,CEP350,NUDT12,PARPBP,RABGGTA,REST,RGS12,NTN4,LRPPRC,GRTP1,RNF4,MBNL2,TRAPPC12,EIF2B1,ELK3,LGR6,CWC27,STK32B,TNFRSF19,POLK,FOXO1,FLT1,STAB2,TM9SF1,MBIP,PAICS,ZNF446,THADA,TMEM132D,WDCP,C1orf112,GABRA2,KDM5B,NMNAT2,JPH4,EAPP,TMEM183A,ZNF274,STRN,MAST4,ZNF544,CNTN2,ACSL6,ARHGEF28,TFDP1,SLC7A8,LINC01551,GZMH,FZD10,GPN1,YTHDC2,ZNF470,PLB1,ANKS1B,IRF1,ZBTB41,ZBED3-AS1,CHPT1,CAB39L,SPRYD7,IFT88,PABPN1,LOX" MicroRNA hsa-miR-362-3p:mirSVR_lowEffct hsa-miR-362-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-28 1.78E-24 4.92E-27 4.51E-26 85 1795 "RALGAPA1,BIRC6,ADD1,NYNRIN,SEMA6A,PPFIA4,UVSSA,AACS,NCOA1,ZNF542P,CADM3,SLC5A6,PNP,CDKL2,CAMK4,LDB2,DCLK1,WDR66,CPNE6,ATAD2B,BOD1L1,HECTD1,ANAPC4,DNM3,NOS1AP,IFT172,MATR3,COG3,PTGS2,PTPRC,F11R,SACS,G3BP2,GNPDA2,PARPBP,FAM129A,ATG10,CLIP4,EFNA5,LATS2,DHRS2,ZNF671,CWC27,SAP18,ETF1,FNIP1,VEZT,ZNF605,POTEM,TMEM132D,CGREF1,SLC22A4,YPEL5,MYO16,KIF21B,PDS5B,ATP8A2,NPAS3,KDM3B,NFASC,ANKLE2,BRD8,PSME4,PPIP5K2,METAP2,GOLGA3,ADGRL3,ADGRA3,LILRB4,ANO4,KHNYN,NT5C1B,GRSF1,AP4S1,ZNF876P,TENT2,YTHDC2,ZNF84,ZMYM2,CAB39L,KIF2A,LETM1,TTC7A,LMNB1,IFT88" MicroRNA hsa-miR-200b:mirSVR_highEffct hsa-miR-200b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.35E-28 1.78E-24 4.92E-27 4.51E-26 85 1795 "COG6,CUL4A,MCFD2,DDX55,BLZF1,WDR19,ARL1,STXBP6,STARD13,NOVA1,CAST,CDK17,CFL2,CHD1,CCDC122,WDFY2,NRXN1,ATAD2B,BOD1L1,HOMER1,TAPT1,COPA,LYSMD3,LACC1,CSNK1G3,FAM169A,FCRL5,DCAF8,ZFYVE16,MATR3,CEP350,OCIAD1,SUPT7L,PARPBP,TSEN15,DNMT3A,EGLN3,B3GLCT,ARGLU1,CRYL1,RNASEL,DLEU1,CLIP1,TRAPPC13,FGF9,RELL1,POLK,FOXG1,MROH9,FOXO1,SUPT20H,G2E3,BRMS1L,MBIP,UFM1,THADA,SLC12A2,NR5A2,ZNF667,KIF21B,ZNF274,MRPS27,NEDD1,IKBIP,COMMD6,MAST4,PSME4,INSM2,METAP2,ADGRL3,C5orf56,EML4,BAZ1A,ATP6V0A2,SLAIN1,VRK2,SPTSSA,LHX9,CHPT1,TMEM178A,TTC41P,RMST,IFT88,LOX,ZNF304" MicroRNA hsa-miR-4276:mirSVR_highEffct hsa-miR-4276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.77E-28 2.01E-24 5.53E-27 5.06E-26 66 1080 "BIRC6,ADD1,SEMA6A,SNX24,ARL1,CCNA1,PNP,CD1E,PAH,PCSK1,PDE4D,PDE6B,CCDC122,ZNF595,GPR180,NRXN1,HECTD1,THAP6,TAPT1,GNPTAB,SNCAIP,ZNF586,SREK1,PTPRC,RB1,SETDB2,EFNA5,MBNL2,SPATA9,MARVELD2,DRAM1,ADGRV1,F7,RELL1,PIBF1,ZCCHC8,RUBCNL,NBEA,BRMS1L,SLC15A4,YPEL5,SNRPF,GABRB1,HSPH1,RBKS,MCCC2,LRCH1,GJA3,RNF212,RNF17,GRSF1,CRB1,TMPO,NPL,ADAMTS19,GUF1,PAPPA2,ZNF10,ZFHX2,IL6ST,CCDC169,FAM49A,KIT,RILPL2,AXDND1,MICU2" MicroRNA hsa-miR-1261:mirSVR_lowEffct hsa-miR-1261:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.85E-28 2.05E-24 5.62E-27 5.15E-26 74 1368 "RALGAPA1,NLN,ANKRD34B,COG6,TBC1D14,UVSSA,APBB2,MSH2,FAM193A,NRL,TAF1B,PCDH9,PIWIL1,CHD1,PFKFB2,CHIT1,ITGBL1,LINC01085,BOD1L1,TOGARAM2,HEATR5A,LYSMD3,NGDN,DNM3,KIAA0040,MPHOSPH8,EIF2AK2,GLT8D2,DMXL1,F11R,G3BP2,FAM228A,TMEM33,ELF1,SNORA49,MPHOSPH9,FCAMR,CWC27,MAEA,IRF9,FCGR3A,TOMM40L,N4BP2L2,TNFRSF19,SUCO,FLT1,ZCCHC8,FBXO11,G2E3,MBIP,IVNS1ABP,THADA,C1orf112,ACIN1,LIMCH1,MYO16,GABRA2,PDS5B,TMEM183A,MAST4,ZNF544,CNTN2,GPR12,STON1,COP1,NCSTN,MSH6,LINC01551,NPL,GPN1,IGF1,SELENOI,NPHS2,FIP1L1" MicroRNA hsa-miR-15b*:mirSVR_highEffct hsa-miR-15b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-28 2.73E-24 7.47E-27 6.84E-26 76 1450 "SLAMF6,NYNRIN,RGS5,MCFD2,MSH2,DDX55,CCDC181,SLC4A4,MYBPC1,RAB29,DAOA,MPZL1,FCHO2,MORN2,CHAMP1,FCGR2C,UHMK1,PAH,SNTG2,ZMYM5,PIWIL1,CFAP54,THAP6,CLOCK,CEP135,PRKD1,SPATA18,FBXL5,OCIAD1,PARPBP,PPP2R3C,FAM129A,CRYL1,RNASEL,LATS2,ELF1,FAM172A,F10,PIBF1,POLK,RUBCNL,BRMS1L,NLRP2,UFM1,C1orf112,GABRB1,ERAP1,CMPK2,RBKS,NEDD1,LRCH1,COMMD6,PPARGC1A,ADGRL3,TCF7,RNF212,CRB1,LINC01551,AP4S1,RASSF6,TMPO,RIMBP2,ADAMTS19,TXK,GUF1,HSD17B4,HTR2A,STARD4,JCHAIN,C12orf73,ANKS1B,CAB39L,TTC41P,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-885-5p:mirSVR_lowEffct hsa-miR-885-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.58E-28 2.97E-24 8.11E-27 7.43E-26 78 1529 "BIRC6,ADD1,ATP6V1G3,ANKRD34B,COG6,NYNRIN,APBB2,WDR19,ARL1,ASCL1,SLC4A4,ATP2B4,ARHGEF7,NOVA1,SNTG2,CDK7,ATAD2B,HOMER1,STRN3,TAPT1,CEP135,ZFYVE16,MATR3,EPS8L1,LOC439933,CEP350,PTPRC,GNPDA2,PARPBP,TSEN15,TMEM161B,TMEM33,PACRGL,TRAPPC12,SPATA9,ELK3,GORAB,SUCO,MROH9,SCYL2,THADA,TADA1,ZNF605,PKD2L2,NR5A2,UGGT2,MEGF10,GABRA2,PDS5B,NMNAT2,CD244,IQGAP2,ANKLE2,IKBIP,GJB2,MAST4,ZNF544,COX7B2,METAP2,MTUS2,ADGRL3,ANO4,ACSL6,DOCK9,RNF212,FCRLA,NPL,SLAIN1,TENT2,YTHDC2,GALP,ZMYM2,ZBTB41,LHX9,ZAR1L,DIAPH3,KIR2DS4,LOX" MicroRNA hsa-miR-135a:mirSVR_lowEffct hsa-miR-135a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.79E-28 3.08E-24 8.40E-27 7.69E-26 87 1892 "MATN3,BIRC6,TMEM132B,ADD1,SEMA6A,EP400,RGS5,MCFD2,UVSSA,CDKL4,NCOA1,ZNF542P,ATP2B4,KCTD12,AP1G2,CACNA1E,CDKL2,SYT2,NFXL1,FCRLB,RGSL1,CHD1,CPNE6,PKP1,AKAP6,TAPT1,SNCAIP,ITSN2,DNM3,DCAF8,SPATA18,SREK1,PTPRC,SACS,RABGAP1L,SETDB2,LRPPRC,MPHOSPH9,TBC1D19,ZNF671,FAM172A,CWC27,SAP18,MAEA,ETF1,DNAJC27,F10,FCGR3A,FCGR3B,NDUFAF7,GORAB,FGF9,FLT1,SUPT20H,TM9SF1,DDX51,P2RX2,UGGT2,MYT1L,KIF21B,NMNAT2,RAPGEF6,ZNF274,GC,LRCH1,ZNF544,PPIP5K2,METAP2,ADGRA3,LILRB4,TCF7,ARHGEF28,KMT5C,GRSF1,GPR161,ADAMTS19,GUF1,RXFP2,UGT2B7,TENT2,NSD2,ZNF470,ZNF84,LMLN,KIR2DL4,KIT,RNASE11" MicroRNA hsa-miR-194:mirSVR_highEffct hsa-miR-194:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.85E-28 3.11E-24 8.46E-27 7.75E-26 62 953 "IL17D,BIRC6,COG6,CUL4A,PITPNM2,APC,KCTD12,ARHGEF7,LDB2,SNTG2,CFL2,CHD1,PFKFB2,WDFY2,MRPL57,BOD1L1,AKAP6,TOGARAM2,HEATR5A,LYSMD3,ZNF586,SREK1,COG3,NR1H4,B3GLCT,TMEM161B,IPO4,PACRGL,RNASEL,MBNL2,ZNF256,TRAPPC13,GORAB,FNIP1,PIBF1,POLK,SELP,MROH9,BRMS1L,IVNS1ABP,TADA1,ZNF605,SLC12A2,PKD2L2,SLC15A4,WDCP,EFR3B,LIMCH1,GABRB1,IQGAP2,SRP72,GJB2,BRD8,MAST4,TBC1D1,METAP2,ARHGEF28,KMT5A,RIMBP2,KCNN2,EP400P1,IFT88" MicroRNA hsa-miR-548v:mirSVR_lowEffct hsa-miR-548v:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.07E-28 3.23E-24 8.73E-27 7.99E-26 78 1531 "MAP1B,MCC,MDM4,KIAA1211,SEMA6A,APAF1,MSH2,ARL1,ATP12A,KCTD12,CAST,AMDHD1,RILPL1,FCHO2,FCGR2C,CD1D,UHMK1,CDK7,PDE4D,PDGFRA,CENPC,PFKFB2,WDFY2,SLC25A3,MRPL57,PIK3C2B,AKAP6,HEATR5A,LYSMD3,CRHBP,DNM3,UBXN2A,FCRL5,SNX17,KLHL3,NUDT12,RABGAP1L,DTD2,POLR1D,UGT2A3,KIRREL1,MPHOSPH9,FAM172A,CWC27,F7,PCBD2,TNFRSF19,PIBF1,SUCO,SDC1,FOXO1,VEZT,PLEKHA6,PAICS,PKD2L2,MYO16,PDS5B,RAPGEF6,NAAA,EAPP,HSPH1,SRP72,ANKLE2,LRCH1,PSME4,ADAM17,STON1,KMT5A,XPO4,COX18,RNF17,ATP6V0A2,KLF12,NSD2,ZNF140,ZMYM2,FIP1L1,AXDND1" MicroRNA hsa-miR-1264:mirSVR_highEffct hsa-miR-1264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.08E-28 3.23E-24 8.73E-27 7.99E-26 82 1689 "MDM4,BIRC6,ACOX3,KIAA1211,MIPEP,KCTD12,AMDHD1,PCDH9,RGSL1,PDGFRA,GPR180,CFAP54,NRXN1,PIK3C2B,THAP6,HOMER1,COPA,LYSMD3,TTC37,ITSN2,UBXN2A,MPHOSPH8,FCRL5,BIVM,SREK1,COG3,DMXL1,FBXL5,LOC439933,TBC1D4,RABGAP1L,RNF219,NR1H4,EGLN3,POLR1D,LGR6,SAP18,MAEA,ABCA11P,TLR6,CLIP1,ELOVL7,FGF9,PIBF1,POLK,SUCO,SDC1,FMO1,FBXO11,PLEKHA6,UFM1,IVNS1ABP,ZNF605,PKD2L2,TMEM132D,SLC15A4,CYP1B1-AS1,MYT1L,UHRF1BP1L,SRP72,ERBIN,IKBIP,KLHL20,PPARGC1A,GPR12,DOCK9,TEP1,RIMBP2,GPN1,TECRL,PAPPA2,HTR2A,WDR36,NSD2,KCNT2,ZBTB41,LHX9,CHPT1,KCNN2,DNAH10,AXDND1,LTA4H" MicroRNA hsa-miR-4308:mirSVR_lowEffct hsa-miR-4308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.60E-28 3.51E-24 9.45E-27 8.66E-26 74 1380 "PPFIA4,MSH2,ATP1A2,KCTD12,ADGRD1,RILPL1,LDB2,FCRLB,SLC5A8,PDE4D,FAM163A,TOGARAM2,CLOCK,CMTM5,NOS1AP,EPS8L1,CEP350,NR1I3,ATG10,RASA1,SMC6,OGFOD2,CLIP4,RNASEL,KLHL12,FAM81B,CWC27,SLC22A17,TMEM129,FCGR3A,TOMM40L,FCGR3B,GORAB,FGFR3,SDC1,FOXG1,FOXO1,NBEA,THADA,CCDC88A,ZNF605,SLC12A2,DCAF11,GABRB1,KIF21B,PDS5B,KDM5B,GJB6,DRC1,GCKR,NEDD1,LRCH1,IKBIP,ZBTB37,ANO4,KHNYN,C1QTNF9B,NCSTN,NT5C1B,NPL,UBE2K,ARHGAP30,HPCAL1,SLAIN1,JCHAIN,ZMYM2,LHX9,KIR2DL4,KIR2DS4,EP400P1,SLAMF9,LINC01913,LCP1,ZNF304" MicroRNA hsa-miR-4255:mirSVR_lowEffct hsa-miR-4255:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.03E-28 3.74E-24 1.01E-26 9.21E-26 80 1613 "RALGAPA1,SFTA3,MATN3,MCC,LRRC43,ACOX3,ADORA1,ATP6V1G3,MIPEP,RGS5,FAM193A,CENPBD1P1,ATP7B,AP1G2,ADGRD1,NOVA1,CAMK4,CAST,DCLK1,PCK2,GLT1D1,CHD1,TSTD1,CFAP54,TM9SF2,THAP6,POU2F1,LYSMD3,CSNK1G3,ITSN2,FAM169A,PRKD1,NOS1AP,ZFYVE16,SREK1,KLHL3,PARPBP,PPP2R3C,NR1H4,RB1,SMC6,LAP3,CLIP4,CRYL1,POLK,FOXG1,FTLP10,FBXO11,BRMS1L,NUBPL,PAICS,SLC22A4,MEGF10,KDM5B,NMNAT2,NAAA,IQGAP2,NPAS3,KDM3B,CMPK2,SRP54,NFASC,LRCH1,IKBIP,ZNF544,UTP20,ADAM17,RNF17,CRB1,BAZ1A,RIMBP2,ADAMTS19,YTHDC2,PLB1,ZBED3-AS1,KIF2A,DIAPH3,EP400P1,CDK2AP1,PABPN1" MicroRNA hsa-miR-764:mirSVR_lowEffct hsa-miR-764:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.22E-28 3.84E-24 1.03E-26 9.42E-26 87 1898 "MATN3,TMEM132B,ADORA1,CDKL4,BLZF1,ARL1,FAM193A,AACS,ASTN1,CENPBD1P1,ZNF542P,CARMIL3,RAB29,CAD,MORN2,SNTG2,RGSL1,GLT1D1,PDE6B,CHIT1,WDFY2,ADGRF3,MPC2,FAM163A,TAPT1,POLE,KIAA0040,FCRL5,EPS8L1,PIGG,COG3,DMXL1,TBC1D4,GNPDA2,LINC01257,WDR1,NR1I3,GALNT14,RNF31,ARGLU1,RGS4,GUSBP3,MBNL2,DHRS2,STX2,MAEA,DNAJC27,TRAPPC13,NDUFAF7,TNFRSF19,SDC1,FOXO1,FLT1,HSD17B7,STAB2,RASA3,NBEA,CGREF1,MYO16,GABRB1,PDS5B,NAAA,MRPS27,KLHL20,GJA3,MAST4,ZNF544,ATP11A,ADGRL3,LILRB4,ACSL6,TCF7,GRSF1,CRB1,TRPC4,TXK,WDR36,FCRL6,LHX9,FAM151B,KCNN2,FIP1L1,KIF2A,KIF3C,KIR2DS4,EP400P1,IFT88" MicroRNA hsa-miR-3174:mirSVR_lowEffct hsa-miR-3174:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.94E-28 4.22E-24 1.13E-26 1.03E-25 80 1616 "MCC,KIAA1211,SLAMF6,BLZF1,ATP1A2,MYH6,NOVA1,DAOA,PCDH9,CDK18,PDE4D,PDGFRA,CENPC,CHIT1,ITGBL1,CPNE6,PIGR,JAKMIP1,THAP6,AKAP6,PM20D1,PREPL,SNCAIP,CSNK1G3,FAM169A,KIAA0040,FCRL5,EIF2AK2,NOS1AP,SREK1,TSEN15,NR1I3,MEMO1,ELK3,TBC1D19,ARSK,ETF1,ABCA11P,USP44,FCAR,TNFRSF19,PIBF1,BRMS1L,IVNS1ABP,ARHGEF40,ZNF605,SLC12A2,C1orf112,EFR3B,KDM5B,JPH4,HSPH1,MRPS27,SRP54,RBKS,MCCC2,NEDD1,LRCH1,GJA3,BRD8,TBC1D1,ADGRL3,DOCK9,KHNYN,HAL,HEXB,HSP90B1,GUF1,TMEM174,SLAIN1,TENT2,PAPPA2,ZNF84,CCDC169,SDR39U1,KCNN2,LINC00442,LETM1,RMST,LMNB1" MicroRNA hsa-miR-130a:mirSVR_highEffct hsa-miR-130a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.24E-28 4.38E-24 1.17E-26 1.07E-25 74 1385 "MATN3,MDM4,BIRC6,KIAA1211,WDR35,ULK1,APAF1,BLZF1,NCOA1,ATP12A,ZNF542P,STARD13,CD84,NFATC4,DAOA,CDKL2,CAST,FCHO2,SNTG2,FAM177A1,PDGFRA,CFL2,JAKMIP1,HOMER1,AKAP6,FAM53A,GNPTAB,LYSMD3,CLOCK,DNM3,PRKD1,DCAF8,FBXL5,NUDT12,CEP120,PARPBP,RASA1,AASDH,MEMO1,ELK3,MPHOSPH9,SAP18,CLIP1,F10,NDUFAF7,N4BP2L2,PEAR1,NBEA,SLC8A1,CCDC88A,WDCP,C1orf112,MEGF10,MYT1L,ERAP1,CMPK2,LRCH1,ERBIN,KLHL20,NPFFR2,INSM2,RNF17,BAZ1A,ADAMTS19,UBC,SLAIN1,TENT2,IRF1,FAM49A,LMLN,CAB39L,DIAPH3,RMST,LIG4" MicroRNA hsa-miR-135b:mirSVR_lowEffct hsa-miR-135b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.53E-28 4.54E-24 1.21E-26 1.10E-25 86 1861 "MATN3,BIRC6,TMEM132B,ADD1,SEMA6A,EP400,RGS5,MCFD2,UVSSA,NCOA1,ZNF542P,ATP2B4,KCTD12,AP1G2,CACNA1E,CDKL2,SYT2,FCRLB,RGSL1,CHD1,CPNE6,PKP1,AKAP6,TAPT1,SNCAIP,ITSN2,DNM3,DCAF8,SPATA18,SREK1,PTPRC,SACS,RABGAP1L,OGFOD2,POLR1D,SETDB2,LRPPRC,GRTP1,MPHOSPH9,TBC1D19,ZNF671,FAM172A,CWC27,SAP18,MAEA,DNAJC27,F10,FCGR3A,FCGR3B,NDUFAF7,GORAB,FGF9,FLT1,TM9SF1,P2RX2,UGGT2,MYT1L,KIF21B,NMNAT2,RAPGEF6,ZNF274,NFASC,GC,ZNF544,PPIP5K2,METAP2,ADGRA3,LILRB4,TCF7,ARHGEF28,KMT5C,GRSF1,GPR161,GUF1,RXFP2,UGT2B7,TENT2,NSD2,ZNF470,ZNF84,LMLN,KIR2DL4,KIR2DS4,KIT,RNASE11,TTC7A" MicroRNA hsa-miR-632:mirSVR_lowEffct hsa-miR-632:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.68E-28 4.62E-24 1.22E-26 1.12E-25 81 1658 "MDM4,KIAA1211,ULK1,BLZF1,ATP1A2,ATP12A,CADM3,ARHGEF7,BTF3,PNP,CAD,RILPL1,ODC1,CHAMP1,CD1E,SCARB1,SNTG2,ZNF664,PDGFRA,GPR180,ITGBL1,POLN,TAPT1,POLE,TOGARAM2,POU2F1,LYSMD3,PREPL,LACC1,DNM3,UBXN2A,CEP350,PTPRC,PARPBP,C14orf119,EGLN3,RGS4,CLIP4,RNASEL,TXNDC15,MBNL2,TRAPPC12,ZNF256,MARVELD2,SAP18,ETF1,F7,FNIP1,TACC3,PAICS,SLC8A1,UGGT2,LIMCH1,MEGF10,CIDEB,FAM114A1,ATP8A2,RBKS,COMMD6,LPIN1,LILRB4,ANO4,GPR12,RNF17,CRB1,ZBTB49,MSH6,TMPO,HEXB,ADAMTS19,SLAIN1,TENT2,VRK2,WDR36,ZNF470,PLB1,ZMYM2,LHX9,TTC41P,AXDND1,IFT88" MicroRNA hsa-miR-140-5p:mirSVR_lowEffct hsa-miR-140-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.78E-28 4.67E-24 1.24E-26 1.13E-25 77 1501 "SLAMF6,HOMEZ,SNX24,RGS5,BLZF1,ARL1,AACS,ASTN1,ATP4B,KCTD12,CADM3,BCL2L2,RAB29,NOVA1,LDB2,CCNB1,CD1D,SCFD2,PCSK1,CDK17,RGSL1,PDGFRA,ITGBL1,CFAP54,AKAP6,POU2F1,VCAN,DNM3,KIAA0040,MATR3,BIVM,CEP350,PTPRC,RABGAP1L,SUPT7L,EGLN3,RB1,EFNA5,LGR6,FAM172A,ARSK,DNAJC27,SLC22A17,TOMM40L,GORAB,RELL1,SUCO,VEZT,FBXO11,UFM1,WDCP,EFR3B,ATP8A2,NFASC,ERBIN,PPARGC1A,BRD8,UGT2A1,ATP11A,ACSL6,ARHGEF28,KMT5A,NCSTN,FCRLA,RNF17,TEP1,GTF2H3,TMPO,RIMBP2,MAEL,TECRL,IL25,PLB1,ZBTB41,KIR2DL4,KIR2DS4,LAD1" MicroRNA hsa-miR-325:mirSVR_lowEffct hsa-miR-325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.13E-28 4.86E-24 1.28E-26 1.17E-25 66 1097 "BIRC6,ANKRD34B,MSH2,WDR19,FAM193A,CCDC181,BTF3,PNP,MPZL1,CD1E,NFXL1,SLC5A8,SCFD2,PDGFRA,CFAP45,ADGRF3,AKAP6,PM20D1,LYSMD3,DNM3,FCRL5,NUDT12,SUPT7L,PARPBP,FAM129A,RB1,SMC6,ELF1,ABCA11P,CLIP1,USP44,GORAB,FOXO1,FLT1,FLT3,FBXO11,NBEA,IVNS1ABP,SLC12A2,MYT1L,RAPGEF6,TMEM183A,IQGAP2,NPFFR2,LPIN1,MAST4,RIPK3,EML4,DOCK9,NCSTN,RNF17,MSH6,AP4S1,RIMBP2,ZNF721,ADAMTS19,ARHGAP30,GUF1,HSD17B4,VRK2,ZNF10,PLB1,SPTSSA,RNASE11,RMST,AXDND1" MicroRNA hsa-miR-573:mirSVR_highEffct hsa-miR-573:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.24E-28 4.91E-24 1.29E-26 1.18E-25 71 1276 "SMIM15,BIRC6,ADD1,APC,CDKL4,DDX55,ARHGAP5,STXBP6,NCOA1,ATP4B,NOVA1,LDB2,SCARB1,PCDH9,CDK17,PGGT1B,AKAP6,TAPT1,THTPA,EPGN,NGDN,VCAN,SPATA18,PTPRC,OCIAD1,TINF2,ATG10,RASA1,DTD2,NTN4,ABCA11P,PCGF3,F7,F10,SH3YL1,FLT1,TADA1,YPEL5,KDM5B,NAAA,NPAS3,SRP54,ERBIN,PCDH17,NPFFR2,LPIN1,GJA3,STRN,PSME4,TMED2,ANO4,ACSL6,GPR18,ARHGEF28,TDG,NT5C1B,LINC01551,MAEL,ZNF721,TNR,GPN1,TXK,KCNT2,ANKS1B,ZBTB41,PGAM5,FAM151B,TMEM178A,KCNN2,CAB39L,AXDND1" MicroRNA hsa-miR-519c-3p:mirSVR_lowEffct hsa-miR-519c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.29E-28 4.94E-24 1.30E-26 1.19E-25 84 1781 "ADD1,WDR35,ARHGAP5,FAM193A,NCOA1,ATP4B,KCTD12,MYH6,ATP7B,BCL2L2,NFATC4,NFKBIA,DAOA,CACNA1E,CDKL2,XPR1,PDE4D,CHD1,PFKFB2,THAP6,HEATR5A,FAM169A,DNM3,NOS1AP,EPS8L1,SREK1,COG3,CEP350,OCIAD1,G3BP2,GNPDA2,WDR1,RNF219,RB1,MEMO1,LRPPRC,EFNA5,LATS2,EIF2B1,MPHOSPH9,CLIP1,IRF9,FGF9,TNFRSF19,POLK,SDC1,PEAR1,FBXO11,NUBPL,SLC8A1,ARHGEF40,SLC12A2,SLC22A5,ZNF667,GABRB1,KIF21B,ZNF274,UHRF1BP1L,NFASC,INSM2,ATP11A,MTUS2,ADGRA3,XPO4,RNF17,CRB1,TMPO,RIMBP2,ATP6V0A2,UBE2K,TENT2,IGF1,KCNT2,ZNF470,ZNF140,ZBTB41,ZBED3-AS1,DIAPH3,KIT,LINC01913,LINC00442,TTC7A,LMNB1,ZNF304" MicroRNA hsa-miR-382:mirSVR_highEffct hsa-miR-382:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.41E-28 5.01E-24 1.31E-26 1.20E-25 74 1388 "MATN3,SMIM15,KIAA1211,CDKL4,MSH2,ATP1A2,ARHGEF7,LINC02347,CDKL2,PCDH9,CDK17,CFL2,ITGBL1,TAPT1,GNPTAB,CRHBP,NGDN,BRI3BP,LACC1,ITSN2,FBXL5,COCH,CEP120,PTPRC,G3BP2,PARPBP,NR1H4,RASA1,ZNF329,SETDB2,EFNA5,TXNDC15,MBNL2,MARVELD2,TBC1D19,DLEU1,TRAPPC13,GORAB,PIBF1,POLK,SUCO,MROH9,FOXO1,VEZT,NBEA,GABRB1,ATP8A2,NPAS3,CMPK2,NEDD1,IKBIP,NPFFR2,PPARGC1A,TMED2,SPIC,ANO4,KMT5A,C1QTNF9B,CRB1,LINC01551,HEXB,GPN1,TXK,SLAIN1,YTHDC2,ZNF470,ZMYM2,ZBED3-AS1,CHPT1,KCNN2,DIAPH3,EP400P1,LAD1,AXDND1" MicroRNA hsa-miR-22*:mirSVR_highEffct hsa-miR-22*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-27 5.37E-24 1.40E-26 1.28E-25 73 1352 "MDM4,ATP6V1G3,DDX55,FAM193A,ASCL1,AACS,NOVA1,CAST,CD1E,PCCA,PFKFB2,CHIT1,ZNF595,WDFY2,TSTD1,LINC01085,THAP6,SYCP3,CLOCK,SNCAIP,LACC1,CEP135,FCRL5,MATR3,PSME1,TINF2,RABGAP1L,RASA1,ZNF329,AASDH,POLR1D,PACRGL,LATS2,ELK3,KLHL12,MARVELD2,DRAM1,MAEA,DLEU1,NDUFAF7,GORAB,TNFRSF19,POLK,SUCO,FLT1,VEZT,NBEA,NUBPL,THADA,CCDC88A,GABRA2,CENPJ,NPAS3,CMPK2,DRC1,ERBIN,PPARGC1A,MAST4,ATP11A,ADAM17,SCFD1,ANO4,LINC01551,RASSF6,RIMBP2,NPL,PAPPA2,YTHDC2,ZMYM2,CHPT1,FIP1L1,AXDND1,LMNB1" MicroRNA hsa-miR-3187:mirSVR_lowEffct hsa-miR-3187:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-27 5.39E-24 1.41E-26 1.29E-25 71 1278 "ABL2,BIRC6,TMEM132B,SLAMF6,HOMEZ,UVSSA,APBB2,BLZF1,ARL1,CENPBD1P1,ZNF542P,STARD13,ADGRD1,PCDH9,FAM177A1,TSTD1,MRPL57,CFAP54,THAP6,HOMER1,STRN3,SNCAIP,CSNK1G3,KIAA0040,NOS1AP,MATR3,EPS8L1,COG3,GNPDA2,PPP2R3C,ATG10,TMEM161B,TRIM28,DNAJC27,PCGF3,CLIP1,NDUFAF7,FOXG1,STAB2,RASA3,FBXO11,THADA,SLC22A5,ACIN1,UGGT2,CYP1B1-AS1,MYO16,KIF21B,JPH4,CENPJ,SRP72,DRC1,MCCC2,LRCH1,ZBTB37,ZNF544,RNF17,CRB1,RIMBP2,MAEL,TNR,LTB4R2,RXFP2,HTR2A,ZNF470,IRF1,NPHS2,ZBED3-AS1,EP400P1,DNAH10,LMNB1" MicroRNA hsa-miR-3123:mirSVR_highEffct hsa-miR-3123:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-27 5.53E-24 1.44E-26 1.31E-25 77 1505 "RALGAPA1,SFTA3,SMIM15,MDM4,SLC4A4,ATP4B,BTF3,RILPL1,FCHO2,NFXL1,PCDH9,PCK2,GPR180,ITGBL1,NRXN1,JAKMIP1,AKAP6,RNASE9,CLOCK,LACC1,DCAF8,BIVM,SREK1,DMXL1,PARPBP,PPP2R3C,EGLN3,ATG10,RB1,ZNF419,SETDB2,RNASEL,TRAPPC12,MAEA,ABCA11P,USP44,FNIP1,N4BP2L2,FGF9,MROH9,FLT1,HSD17B7,RUBCNL,FBXO11,G2E3,TMEM132D,SLC22A4,UGGT2,LIMCH1,PDS5B,IQGAP2,ERAP1,ATP8A2,OXGR1,NPAS3,NFASC,LILRB1,PSME4,ZNF544,UTP20,GOLGA3,ADGRL3,TDG,FCRLA,NT5C1B,BAZ1A,GZMH,TMPO,MAEL,ZNF721,PAPPA2,HTR2A,KCNT2,JCHAIN,ZBED3-AS1,KIR2DL4,LMNB1" MicroRNA hsa-miR-211:mirSVR_highEffct hsa-miR-211:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.08E-27 5.72E-24 1.48E-26 1.36E-25 79 1584 "SMIM15,SEMA6A,DDX55,AACS,ATP2B4,STARD13,NOVA1,CACNA1E,PCDH9,FAM177A1,PDE4D,CFL2,VIT,PGGT1B,CFAP54,ATAD2B,UGT2B28,AKAP6,LACC1,DCAF8,PSME1,PIGG,COG3,FBXL5,LOC439933,COCH,G3BP2,RABGAP1L,PARPBP,TSEN15,DTD2,CLIP4,SETDB2,LATS2,GRTP1,BORA,ETF1,DLEU1,ELOVL7,TMEM156,FNIP1,RELL1,POLK,SUCO,FLT3,VEZT,NBEA,SLC30A6,ZNF605,DCAF11,GABRA2,MYT1L,GABRB1,ZNF274,ERAP1,HSPH1,PCDH17,MIMT1,PPARGC1A,ADAM17,METAP2,NCSTN,RNF17,GPR161,GTF2H3,GZMH,TMPO,NPL,GPN1,ARHGAP30,CCDC190,ZMYM2,LINC00272,ZBED3-AS1,TMEM178A,TTC41P,SPRYD7,LMNB1,PABPN1" MicroRNA hsa-miR-323-3p:mirSVR_highEffct hsa-miR-323-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-27 5.92E-24 1.53E-26 1.40E-25 71 1280 "ADD1,SLAMF6,ANKRD34B,TBC1D14,APC,ARL1,ATP2B4,STARD13,KCTD12,NEDD8,FCRL3,ARHGEF7,NOVA1,DAOA,FCHO2,UHMK1,PDE4D,RCBTB2,NRXN1,TAPT1,IL20,SPATA18,COG3,FBXL5,TBC1D4,OCIAD1,G3BP2,C12orf42,PARPBP,B3GLCT,ELK3,FAM172A,SH3YL1,FNIP1,SUCO,FLT1,SUPT20H,SCYL2,TADA1,PKD2L2,N4BP2,UGGT2,MYT1L,GABRB1,CENPJ,TMEM183A,ERAP1,NPAS3,CMPK2,LRCH1,ERBIN,GJB2,ATP11A,GOLGA3,ADGRL3,ADGRA3,RNF212,TDG,RNF17,LINC01551,TMPO,NPL,UBE2K,SLAIN1,ZNF10,ANKS1B,ZMYM2,KIF2A,TTC41P,RMST,SPRYD7" MicroRNA hsa-miR-183:mirSVR_lowEffct hsa-miR-183:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-27 5.93E-24 1.53E-26 1.40E-25 83 1745 "MATN3,SNX24,AACS,ATP2B4,BCL2L2,ARHGEF7,NOVA1,CACNA1E,MPZL1,LDB2,CCNB1,CD1E,SCARB1,PCDH9,PDE4D,CFL2,VIT,PKP1,HECTD1,C1orf116,AKAP6,LYSMD3,CSNK1G3,C12orf65,DNM3,PRKD1,NOS1AP,FBXL5,KLHL3,PTPRH,TINF2,GNPDA2,DNMT3A,TMEM161B,CLIP4,MBNL2,LGR6,DEPDC4,EFS,ELOVL7,TRAPPC13,TMEM129,NDUFAF7,PIBF1,POLK,FOXO1,SUPT20H,VEZT,FBXO11,G2E3,STPG4,ZNF605,CGREF1,SLC22A4,GABRB1,PDS5B,NMNAT2,ATP8A2,HSPH1,PPARGC1A,STRN,BRD8,PSME4,METAP2,ANO4,TDG,RNF17,LINC01551,WDR36,ZNF10,MZF1,ZNF470,PLB1,IRF1,ZBED3-AS1,CHPT1,KCNN2,ANKDD1B,DIAPH3,KIR2DL4,LINC01913,IFT88,PABPN1" MicroRNA hsa-miR-455-3p:mirSVR_lowEffct hsa-miR-455-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-27 6.04E-24 1.55E-26 1.42E-25 82 1705 "MDM4,ADD1,KIAA1211,COG6,SEMA6A,FAM193A,B4GALT3,PPP1R12B,FGFRL1,BCL2L2,CD84,NFATC4,ARHGEF7,NFKBIA,LINC02347,PNP,DAOA,CAD,SCARB1,PCDH9,XPR1,CHD1,NRXN1,C1orf116,GNPTAB,POU2F1,NCOR2,DCAF8,SNX17,BIVM,PIGG,CEP350,CEP120,OCIAD1,G3BP2,PARPBP,C14orf119,RABGGTA,GALNT14,B3GLCT,AASDH,RNASEL,EFNA5,TXNDC15,GRTP1,ETF1,FGFR3,RELL1,DDX51,NUBPL,PAICS,SLC8A1,ZNF605,C1orf112,MEGF10,EAPP,TMEM183A,HSPH1,PPARGC1A,STRN,PPIP5K2,ADGRA3,STON1,DOCK9,GRSF1,CRB1,TMPO,HEXB,UBE2K,GPN1,PAPPA2,ZNF470,PLB1,KCNJ9,CAB39L,KIT,TTC41P,LAD1,RMST,AXDND1,LMNB1,SPATA13" MicroRNA hsa-miR-3166:mirSVR_lowEffct hsa-miR-3166:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-27 6.32E-24 1.62E-26 1.48E-25 86 1870 "RALGAPA1,SEMA6A,HOMEZ,MSH2,SLC4A4,CD84,ADGRD1,MPZL1,DCLK1,PCSK1,CDK17,CENPC,RCBTB2,PFKFB2,SMIM14,PIK3C2B,PTPRVP,PMCH,AKAP6,TAPT1,GNPTAB,CLOCK,CSNK1G3,FAM169A,DNM3,MATR3,SNX17,SPATA18,LOC439933,CEP350,KLHL3,TBC1D4,RABGAP1L,NR1I3,DNMT3A,B3GLCT,AASDH,TMEM33,GUSBP3,PACRGL,KLHL12,MPHOSPH9,ZNF219,EFS,CWC27,PCGF3,TRAPPC13,FNIP1,FLT1,STAB2,PLEKHA6,SCYL2,THADA,SLC12A2,POTEM,TMEM132D,SLC22A4,NR5A2,EFR3B,DCAF11,GABRB1,EAPP,ATP8A2,CMPK2,ANKLE2,LRCH1,COMMD6,AURKC,PSME4,ATP11A,PPIP5K2,ADGRL3,ARHGEF28,C1QTNF9B,RNF17,SLC7A8,AP4S1,RAB2B,ADAMTS19,UBE2K,IRF1,FAM49A,KIR2DL1,KIR3DL1,KIR3DL2,RMST" MicroRNA hsa-miR-300:mirSVR_highEffct hsa-miR-300:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-27 6.54E-24 1.67E-26 1.53E-25 77 1509 "BIRC6,NLN,APAF1,AACS,ATP2B4,CARMIL3,FCRL3,NFKBIA,RAB29,CDKL2,FCHO2,LDB2,PCCA,FAM177A1,CENPC,CFL2,ZNF595,NRXN1,BOD1L1,HECTD1,IL20,CSNK1G3,LRRTM2,BIVM,PTGS2,NUDT12,TBC1D4,OCIAD1,G3BP2,RABGAP1L,RAN,EGLN3,ATG10,TMEM161B,DTD2,NTN4,TXNDC15,MBNL2,MPHOSPH9,TCTN2,ARSK,ETF1,DLEU1,ABCA11P,ELOVL7,FNIP1,TNFRSF19,FOXG1,NBEA,NR5A2,GABRA2,PDS5B,KDM5B,RAPGEF6,OXGR1,MRPS27,CMPK2,NEDD1,KLHL20,GJA3,ADAM17,ADGRA3,ANO4,AP4S1,ACTR6,ZNF721,HAL,ATP6V0A2,TRPC4,MZF1,SPTSSA,ANKS1B,LHX9,KIT,DNAH10,CDK2AP1,LOX" MicroRNA hsa-miR-410:mirSVR_highEffct hsa-miR-410:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.26E-27 6.69E-24 1.71E-26 1.56E-25 84 1789 "RALGAPA1,MATN3,ACOX3,COG6,WDR35,ARHGAP5,STXBP6,CADM3,AMDHD1,FCHO2,FAM177A1,CHD1,CCDC122,SNX6,AKAP6,TAPT1,LYSMD3,SNCAIP,CSNK1G3,CEP135,PRKD1,DDX59,MATR3,SPATA18,PSME1,PIGG,TBC1D4,PTPRC,OCIAD1,SACS,TSEN15,B3GLCT,ARGLU1,TMEM161B,AASDH,DTD2,LAP3,NTN4,ELK3,MARVELD2,BORA,PCGF3,FGF9,TNFRSF19,SUPT20H,SLC34A2,G2E3,CCDC92,UFM1,IVNS1ABP,ARHGEF40,N4BP2,YPEL5,UGGT2,PDS5B,NMNAT2,ZNF274,UHRF1BP1L,NEDD1,LRCH1,PCDH17,PSME4,UGT2A1,UTP20,PPIP5K2,ADGRL3,ADGRA3,C5orf56,GPR18,STON1,DOCK9,FCRLA,RAB2B,NPL,NLRP8,VRK2,STARD4,ZMYM2,ZBED3-AS1,LMLN,KCNN2,FIP1L1,TTC41P,TTC7A" MicroRNA hsa-miR-26b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-27 7.31E-24 1.86E-26 1.70E-25 86 1874 "MAP1B,MATN3,MCC,EP400,APBB2,FAM193A,CCNB1IP1,CCDC181,MYBPC1,ATP7B,CAD,CDKL2,CAMK4,LDB2,ZNF664,PCCA,FAM177A1,PCSK1,CDK18,PDGFRA,RCBTB2,ATAD2B,MPC2,POU2F1,CLOCK,MPHOSPH8,DCAF8,MATR3,PSME1,PTGS2,TINF2,SACS,G3BP2,RABGAP1L,RABGGTA,RB1,CRYL1,GRTP1,DCUN1D2,EIF2B1,TCTN2,PCOTH,ETF1,TRAPPC13,TMEM156,FGF9,FGFR3,SUCO,FOXG1,ZCCHC8,SLC34A2,FBXO11,MBIP,IVNS1ABP,P2RX2,MYT1L,KIF21B,ERAP1,ERBIN,BRD8,MAST4,UGT2A1,ADAM17,METAP2,KMT5A,TGFBI,TGM1,HEXB,TPO,UBE2K,TRPC4,TXK,GUF1,IGF1,ZNF84,ZNF324B,ZNF140,KCNN2,CAB39L,RPGRIP1,TRPC7,LETM1,LIG4,LMNB1,LTA4H,MICU2" MicroRNA hsa-miR-124*:mirSVR_highEffct hsa-miR-124*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-27 8.70E-24 2.21E-26 2.02E-25 63 1005 "IL17D,MCFD2,APC,FAM193A,SLC4A4,NLRP4,ARHGEF7,RAB29,CACNA1E,ZNF664,PCDH9,DCLK1,CDK17,PDGFRA,VIT,BOD1L1,CRHBP,LACC1,CEP135,FCRL5,BIVM,COG3,COCH,PTPRC,B3GLCT,RASA1,RB1,AASDH,RGS4,NTN4,ELK3,SLC22A17,ELOVL7,TRAPPC13,PIBF1,SUCO,FOXG1,SLC12A2,LIMCH1,KIF21B,ALLC,JPH4,HSPH1,MRPS27,MIMT1,ZBTB37,PSME4,ADGRL3,STON1,KMT5A,LINC01551,GTF3C2,RAB2B,FZD10,ADAMTS19,C12orf73,PLB1,SPTSSA,IRF1,ZBED3-AS1,CHPT1,KCNN2,CAB39L" MicroRNA hsa-miR-3170:mirSVR_lowEffct hsa-miR-3170:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-27 9.04E-24 2.29E-26 2.09E-25 80 1635 "KIAA1211,FAM193A,ASCL1,AACS,ATP1A2,BCL2L2,ARHGEF7,CCNA1,NOVA1,DAOA,CAST,FCGR2C,CD1D,CD1E,PCSK1,WDFY2,GPR180,CFAP54,HOMER1,LYSMD3,CLOCK,C12orf65,CEP135,DNM3,CMTM5,UBXN2A,F11R,DNMT3A,ATG10,ZNF329,PACRGL,DCUN1D2,GP6,STK32B,FCGR3A,UTP15,FCGR3B,N4BP2L2,HSD17B7,FMO1,GOLGA2P5,RUBCNL,DDX51,UFM1,SLC12A2,CGREF1,SLC22A4,YPEL5,DCAF11,ERAP1,NFASC,IKBIP,MIMT1,PPARGC1A,MAST4,LILRB4,C5orf56,RIPK3,DOCK9,SNRNP35,COX18,NCSTN,FCRLA,TEP1,CRB1,MAEL,TPO,ZNF876P,TENT2,ZNF10,ZNF470,SELENOI,IL6ST,KIR2DS4,TTC41P,SLAMF9,SPRYD7,LMNB1,IFT88,ZNF304" MicroRNA hsa-miR-1248:mirSVR_highEffct hsa-miR-1248:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.70E-27 9.05E-24 2.29E-26 2.09E-25 76 1478 "RALGAPA1,MCC,MDM4,NDRG2,ANKRD34B,CENPBD1P1,ATP1A2,STARD13,NFKBIA,NOVA1,DAOA,CD1D,UHMK1,CHIT1,ZNF595,GPR180,NRXN1,THAP6,EPGN,SNCAIP,LACC1,CSNK1G3,GALNT9,C12orf65,EIF2AK2,MATR3,SNX17,LOC439933,NUDT12,PTPRC,TSEN15,DNMT3A,NTN4,SETDB2,PACRGL,TXNDC15,GRTP1,ARSK,CWC27,USP44,PIBF1,POLK,UFM1,THADA,JPH4,OXGR1,NPAS3,SRP72,DRC1,ANKLE2,IKBIP,PCDH17,PPARGC1A,ATP11A,METAP2,ANO4,C5orf56,STON1,DOCK9,RNF17,CRB1,AP4S1,MAEL,HEXB,PAPPA2,ZMYM2,LINC00272,LHX9,FAM151B,ANKDD1B,FIP1L1,CAB39L,RNASE11,AXDND1,LMNB1,PABPN1" MicroRNA hsa-miR-4325:mirSVR_lowEffct hsa-miR-4325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-27 9.63E-24 2.43E-26 2.22E-25 75 1441 "MATN3,SEMA6A,PITPNM2,SNX24,RGS5,NCOA1,CENPBD1P1,SLC5A6,NOVA1,CD1D,PCK2,ZMYM5,XPR1,CDK7,RGSL1,PDE4D,RCBTB2,PFKFB2,PGGT1B,COLEC11,ADGRF3,THAP6,HEATR5A,LACC1,CSNK1G3,VCAN,UBXN2A,ZFYVE16,SPATA18,COG3,SACS,RABGAP1L,LINC01257,WDR1,PARPBP,PPP2R3C,RB1,SLC9C2,RGS4,LAP3,POLR1D,NTN4,GUSBP3,MBNL2,CWC27,SULT6B1,N4BP2L2,FGF9,RUBCNL,BRMS1L,UFM1,SLC8A1,CCDC88A,POTEM,WDCP,SLC22A5,LIMCH1,MRPS27,SRP54,LRCH1,IKBIP,PPARGC1A,GJA3,EML4,NPL,TENT2,STARD4,YTHDC2,IGF1,LINC00272,LHX9,FAM151B,CHPT1,TMEM178A,KCNN2" MicroRNA hsa-miR-3152:mirSVR_lowEffct hsa-miR-3152:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-27 1.10E-23 2.76E-26 2.52E-25 73 1368 "SFTA3,MATN3,TMEM132B,TBC1D14,SEMA6A,SNX24,APC,ASCL1,ARHGEF7,NOVA1,NRL,AMDHD1,CD1E,UHMK1,PCDH9,PCK2,CDK17,PDE4D,CHD1,NRXN1,PIGR,HOMER1,LYSMD3,CLOCK,PREPL,SNCAIP,CEP135,DCAF8,COG3,PTPRC,SUPT7L,NR1H4,RB1,CLIP4,POLR1D,NTN4,SETDB2,LRPPRC,EIF2D,MBNL2,USP44,PCBD2,FOXG1,SLC30A6,CCDC88A,SLC12A2,N4BP2,C1orf112,SLC22A4,EFR3B,MYT1L,CIDEB,IQGAP2,ERAP1,NPAS3,KDM3B,SRP54,RBKS,LRCH1,STRN,PSME4,ATP11A,ADGRL3,HMGCR,TECRL,RXFP2,HSD17B4,PLB1,ANKS1B,DIAPH3,LINC00442,IFT88,LOX" MicroRNA hsa-miR-34a*:mirSVR_highEffct hsa-miR-34a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-27 1.15E-23 2.89E-26 2.65E-25 65 1079 "RALGAPA1,SMIM15,APAF1,CDKL4,KCTD12,CCNA1,CHAMP1,CD1E,ZNF664,FAM177A1,CENPC,CFL2,PIWIL1,AKAP6,HEATR5A,IL20,CSNK1G3,ZFYVE16,COG3,PTGS2,NUDT12,TBC1D4,PTPRC,G3BP2,WDR1,AASDH,SLC9C2,SETDB2,TBC1D19,GMPR2,TMEM156,NDUFAF7,GORAB,N4BP2L2,FGF9,POLK,MROH9,G2E3,SCYL2,IVNS1ABP,SLC12A2,PKD2L2,SLC15A4,SLC22A5,PDS5B,KDM5B,KDM3B,CMPK2,SRP72,MCCC2,PCDH17,PPARGC1A,BRD8,ADGRL3,EML4,RNF212,TFDP1,TPO,GPN1,ARHGAP30,HMGCR,RXFP2,PLB1,ZNF140,AXDND1" MicroRNA hsa-miR-1273d:mirSVR_lowEffct hsa-miR-1273d:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.30E-27 1.22E-23 3.05E-26 2.80E-25 77 1524 "RALGAPA1,LRRC43,TMEM132B,NYNRIN,MCFD2,APAF1,NCOA1,ASTN1,CADM3,CD84,PNP,CACNA1E,ODC1,CCNB1,FCRLB,ZMYM5,PCSK1,CDK18,RGSL1,PDE4D,WDFY2,UGT2B28,THAP6,LYSMD3,NGDN,IL20,CSNK1G3,IFT172,PIGG,PTPRC,DHFR,C14orf119,ATG10,ZNF329,SMC6,UGT2A3,STX2,ARSK,NDUFAF7,TNFRSF19,MROH9,FLT1,IVNS1ABP,THADA,LIMCH1,ERAP1,MRPS27,SRP72,COMMD6,PPARGC1A,GJA3,PSME4,UTP20,LINC02393,ADAM17,MTUS2,ADGRL3,TCF7,KMT5A,KHNYN,NCSTN,RNF17,CRB1,ZBTB49,RIMBP2,HSP90B1,UBE2K,RXFP2,WDR36,TADA2B,ZNF470,ANKS1B,ZBTB41,CHPT1,EP400P1,RMST,SPATA13" MicroRNA hsa-miR-1294:mirSVR_lowEffct hsa-miR-1294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-27 1.23E-23 3.07E-26 2.81E-25 81 1683 "MCC,COG6,CUL4A,ZNF784,CENPBD1P1,SLC4A4,ATP2B4,STARD13,MYH6,ATP7B,SLC5A6,AP1G2,FCHO2,NFXL1,PCSK1,CDK17,RGSL1,GLT1D1,CFL2,ZNF595,WDFY2,UGT2B28,C1orf116,POLE,POU2F1,LYSMD3,NGDN,VCAN,KIAA0040,UBXN2A,SPATA18,PIGG,DCT,PPP2R3C,B3GLCT,RNF31,RB1,DTD2,RGS12,POLR1D,TXNDC15,TRIM28,LGR6,DHRS2,GMPR2,CLIP1,F7,TRAPPC13,PCBD2,G2E3,DDX51,UFM1,STPG4,CCDC88A,CGREF1,C1orf112,MYO16,PDS5B,IQGAP2,NPAS3,LRCH1,PPIP5K2,ADGRL3,C5orf56,RIPK3,ARHGEF28,EML4,KHNYN,RAB2B,ADAMTS19,KLF12,GPN1,PAPPA2,ZFHX2,ZNF324B,PLB1,FAM49A,TMEM178A,EP400P1,TTC41P,RMST" MicroRNA hsa-miR-25:mirSVR_highEffct hsa-miR-25:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.52E-27 1.34E-23 3.33E-26 3.05E-25 63 1013 "MAP1B,KIAA1211,PITPNM2,CDKL4,ATP2B4,STARD13,NOVA1,FCHO2,LDB2,CD1D,ZNF595,GPR180,NUP37,JAKMIP1,HECTD1,AKAP6,STRN3,CRHBP,C12orf65,FAM169A,ZNF586,COG3,DMXL1,CEP350,SACS,G3BP2,C14orf119,FAM129A,LAP3,LATS2,RNF4,ABCA11P,PCGF3,USP44,FNIP1,POLK,FBXO11,BRMS1L,ALKAL2,ZNF605,SLC12A2,PDS5B,NAAA,IQGAP2,NPAS3,RBKS,LRCH1,ZNF544,METAP2,GOLGA3,ANO4,GPR12,DOCK9,TMPO,FZD10,ZNF721,TENT2,KCNT2,DIAPH3,RMST,AXDND1,LIG4,LMNB1" MicroRNA hsa-miR-4273:mirSVR_highEffct hsa-miR-4273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.66E-27 1.42E-23 3.51E-26 3.21E-25 66 1118 "MATN3,MDM4,ANKRD34B,AACS,CAST,CD1D,ZNF664,RGSL1,PDGFRA,GLT1D1,PDE6B,NRXN1,AKAP6,FAM53A,SNCAIP,LACC1,PRKD1,ZNF586,MATR3,FBXL5,WDR1,PPP2R3C,DNMT3A,FAM129A,B3GLCT,RASA1,REST,RNASEL,EFNA5,UGT2A3,MARVELD2,BORA,FAM172A,CWC27,MAEA,FCGR2B,TOMM40L,GORAB,FOXG1,GOLGA2P5,PAICS,SLC12A2,SLC15A4,YPEL5,GABRA2,ATP8A2,OXGR1,RBKS,PCDH17,NPFFR2,STRN,TMED2,CRB1,LINC01551,GZMH,HEXB,VRK2,YTHDC2,ZNF26,JCHAIN,SPTSSA,ZMYM2,RMST,NUAK2,IFT88,LOX" MicroRNA hsa-miR-490-3p:mirSVR_lowEffct hsa-miR-490-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.82E-27 1.50E-23 3.71E-26 3.39E-25 74 1413 "RALGAPA1,MCC,MDM4,SEMA6A,CENPBD1P1,ATP2B4,ATP4B,KCTD12,BCL2L2,LINC02347,CACNA1E,CDK17,GLT1D1,PDE6B,CCDC122,ZNF595,PIGR,LTB4R,PTPRVP,THAP6,CLOCK,VCAN,PRKD1,FCRL2,SPATA18,PXMP2,RB1,RGS12,RNASEL,TXNDC15,GRTP1,ELF1,MARVELD2,FAM172A,ETF1,DLEU1,ADGRV1,ELOVL7,TRAPPC13,FCAR,TNFRSF19,FOXG1,FMO1,NBEA,SLC8A1,UGGT2,PDS5B,KDM5B,RAPGEF6,CENPJ,NAAA,TMEM183A,ZNF274,ERAP1,NFASC,IKBIP,GJB2,ANO4,STON1,DOCK9,TEP1,RASSF6,RAB2B,TNR,NPL,HEXB,UBE2K,GUF1,ZNF550,NSD2,ZNF10,ZNF84,SDR39U1,KIR3DL2" MicroRNA hsa-miR-593:mirSVR_lowEffct hsa-miR-593:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.84E-27 1.51E-23 3.73E-26 3.42E-25 87 1936 "SFTA3,ATP6V1G3,COG6,DDX55,ZNF784,NCOA1,CENPBD1P1,FGFRL1,PROZ,CCNA1,RAB29,XPR1,CDK17,RGSL1,GLT1D1,PFKFB2,ITGBL1,BOD1L1,THAP6,POU2F1,SNCAIP,GALNT9,ZNF586,EPS8L1,PSME1,LOC439933,MTX3,TSEN15,FAM129A,B3GLCT,ATG10,ZNF329,RGS4,RGS12,CLIP4,NTN4,GUSBP3,PACRGL,RNASEL,TRAPPC12,LGR6,ZNF671,ETF1,PCGF3,F7,UTP15,GORAB,N4BP2L2,FGFR3,SUCO,HSD17B7,FBXO11,UFM1,N4BP2,WDCP,YPEL5,EFR3B,LIMCH1,NAAA,ZNF274,CD244,MCCC2,PPARGC1A,ATP11A,RNF212,NCSTN,TEP1,NT5C1B,TFDP1,GPR161,ZBTB49,LINC01551,GTF3C2,FZD10,ADAMTS19,FCRL6,ZNF324B,PLB1,CCDC190,ANKS1B,LHX9,FAM151B,ZBED3-AS1,CHPT1,NUAK2,AXDND1,LOX" MicroRNA hsa-miR-1253:mirSVR_highEffct hsa-miR-1253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.96E-27 1.57E-23 3.87E-26 3.54E-25 80 1649 "COG6,CUL4A,SNX24,ARL1,AACS,ZNF542P,SLC5A6,PNP,CAD,AMDHD1,LDB2,ZNF664,PCDH9,PCSK1,ZNF595,HOMER1,CEP135,FCRL5,FCRL2,DCAF8,ZFYVE16,DMXL1,CEP120,SUPT7L,PARPBP,AASDH,RGS4,MEMO1,DCUN1D2,UGT2A3,LGR6,GP6,FAM172A,ARSK,SLC22A17,FCAR,TNFRSF19,RELL1,PIBF1,POLK,VEZT,RUBCNL,UFM1,IVNS1ABP,CCDC88A,SLC12A2,WDCP,SLC22A5,CHFR,MEGF10,NAAA,ERAP1,MRPS27,RBKS,ERBIN,MIMT1,ZNF544,PPIP5K2,ADGRL3,ANO4,ACSL6,RIPK3,STON1,EML4,TFDP1,GTF3C2,MAEL,WDR36,KCNT2,IL6ST,GALP,CHPT1,TMEM178A,ANKDD1B,MFSD2B,RMST,NUAK2,LMNB1,CDK2AP1,PABPN1" MicroRNA hsa-miR-664*:mirSVR_lowEffct hsa-miR-664*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-27 1.65E-23 4.06E-26 3.71E-25 83 1772 "ABL2,MAP1B,SLAMF6,NYNRIN,TBC1D14,HOMEZ,EP400,RGS5,UVSSA,AACS,CENPBD1P1,ATP1A2,SLC4A4,STARD13,BCL2L2,CD84,FCRL3,SLC5A6,RAB29,MPZL1,PCDH9,DCLK1,FAM177A1,XPR1,CDK7,CFL2,CPNE6,PIGR,SMIM14,POLN,THAP6,FAM163A,TAPT1,CLOCK,SNCAIP,CSNK1G3,C12orf65,KIAA0040,COG3,F11R,RABGAP1L,SLC35F6,WDR1,DNMT3A,EGLN3,B3GLCT,CLIP4,TXNDC15,MPHOSPH9,TBC1D19,DNAJC27,CLIP1,GORAB,FNIP1,FGF9,TNFRSF19,FBXO11,G2E3,DDX51,IVNS1ABP,CCDC88A,UGGT2,LIMCH1,PDS5B,CENPJ,ZNF274,ATP8A2,KDM3B,MCCC2,IKBIP,ADAM17,CRB1,ZBTB49,AP4S1,ADAMTS19,GPN1,HSD17B4,RILPL2,LETM1,RMST,NUAK2,SPRYD7,IFT88" MicroRNA hsa-miR-1278:mirSVR_highEffct hsa-miR-1278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-27 1.69E-23 4.13E-26 3.79E-25 57 820 "WDR19,CCNA1,ADGRD1,RILPL1,UHMK1,ZMYM5,HOMER1,PMCH,TAPT1,RCHY1,EPGN,C12orf65,CEP135,CTSG,BIVM,SREK1,NUDT12,PPP2R3C,DCUN1D2,GP6,GMPR2,ELOVL7,POLK,STAB2,SUPT20H,SGCG,BRMS1L,MBIP,UFM1,IVNS1ABP,CCDC88A,SLC12A2,N4BP2,NR5A2,MYO16,CENPJ,EAPP,ATP8A2,NPAS3,MRPS27,KDM3B,ERBIN,PPARGC1A,ADGRL3,ADGRA3,RNF212,GTF3C2,BAZ1A,ADAMTS19,NSD2,ZNF26,C12orf73,IL6ST,ANKS1B,CHPT1,KIT,MICU2" MicroRNA hsa-miR-190:mirSVR_highEffct hsa-miR-190:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.35E-27 1.78E-23 4.35E-26 3.98E-25 68 1194 "MAP1B,MATN3,TBC1D14,APAF1,NCOA1,ASTN1,TAF1B,CD1E,PAH,ZNF664,PCDH9,RCBTB2,MRPL57,NRXN1,UGT2B28,HOMER1,COPA,CLOCK,LRRTM2,DCAF8,PSME1,DMXL1,NUDT12,G3BP2,TSEN15,DNMT3A,TMEM161B,SMC6,REST,PACRGL,RNF4,CWC27,SAP18,GMPR2,ELOVL7,SH3YL1,TRAPPC13,SULT6B1,FNIP1,TNFRSF19,NBEA,UFM1,IVNS1ABP,ZNF605,P2RX2,MRPS14,MEGF10,RAPGEF6,IQGAP2,CMPK2,MCCC2,PCDH17,SULT1E1,PPARGC1A,ANO4,ARHGEF28,DOCK9,CRB1,AP4S1,RIMBP2,HEXB,ADAMTS19,TXK,GUF1,C12orf73,CCDC169,ZNF140,DIAPH3" MicroRNA hsa-miR-543:mirSVR_highEffct hsa-miR-543:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.41E-27 1.82E-23 4.43E-26 4.06E-25 81 1693 "MAP1B,MDM4,BIRC6,ARL1,CD1D,NFXL1,ZMYM5,PCSK1,WDR66,CENPC,RCBTB2,GPR180,LINC01085,UGT2B28,AKAP6,CLOCK,VCAN,CEP135,ZFYVE16,MATR3,SREK1,COG3,PTGS2,DMXL1,FBXL5,CEP350,PTPRC,SACS,SUPT7L,NR1I3,B3GLCT,ATG10,RB1,SMC6,ZNF419,TXNDC15,SPATA9,KLHL12,FCAMR,STX2,ETF1,ABCA11P,ADGRV1,CLIP1,GORAB,BRMS1L,TADA1,MRPS14,ZNF667,DCAF11,MYT1L,PDS5B,UHRF1BP1L,NPAS3,MRPS27,NPFFR2,PPARGC1A,ZNF544,TBC1D1,METAP2,ADGRA3,YIPF7,FCRLA,TFDP1,CRB1,TGFBI,MAEL,ADAMTS19,HSP90B1,HMGCR,TXK,SLAIN1,POC5,CCDC169,ANKS1B,ZMYM2,LHX9,ZBED3-AS1,LCP1,AXDND1,LOX" MicroRNA hsa-miR-4320:mirSVR_lowEffct hsa-miR-4320:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.66E-27 1.95E-23 4.74E-26 4.34E-25 73 1381 "NYNRIN,HOMEZ,CUL4A,APC,NCOA1,ZNF542P,ATP2B4,MYH6,ATP7B,CDKL2,SYT2,FCHO2,LDB2,FCGR2C,CD1E,DCLK1,PDE4D,ITGBL1,NRXN1,PIK3C2B,ATAD2B,PTPRVP,FAM163A,SNCAIP,DNM3,UBXN2A,NOS1AP,DCAF8,MATR3,FBXL5,G3BP2,RAN,EGLN3,B3GLCT,NTN4,ELF1,CWC27,STK32B,DNAJC27,ADGRV1,PCGF3,SLC22A17,NDUFAF7,SUCO,PEAR1,NBEA,PLEKHA6,ALKAL2,STPG4,SCYL2,SLC12A2,PKD2L2,TMEM132D,UGGT2,DRC1,PPIP5K2,METAP2,ADGRL3,GPR12,STON1,EML4,BAZ1A,RASSF6,GZMH,GPN1,SLAIN1,NSD2,IL6ST,PLB1,LMLN,SLAMF9,SPRYD7,PABPN1" MicroRNA hsa-miR-101*:mirSVR_highEffct hsa-miR-101*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.82E-27 2.03E-23 4.93E-26 4.51E-25 60 920 "MATN3,SLAMF6,WDR35,APAF1,ARHGAP5,CCDC181,STARD13,KCTD12,ARHGEF7,CCNA1,DAOA,CAST,FCHO2,PCCA,FAM177A1,CHD1,HOMER1,HEATR5A,NGDN,GLT8D2,DDX59,ZNF586,ZFYVE16,PIGG,SREK1,PTGS2,NUDT12,OCIAD1,NR1H4,FAM129A,RASA1,RB1,LAP3,MBNL2,ABCA11P,ELOVL7,NDUFAF7,GORAB,PIBF1,SUCO,FOXO1,FLT1,FMO1,UFM1,CCDC88A,YPEL5,CHFR,MEGF10,ERAP1,DRC1,IKBIP,COMMD6,ACSL6,BAZ1A,FZD10,HSD17B4,FAM151B,CHPT1,TTC41P,LOX" MicroRNA hsa-let-7i:mirSVR_lowEffct hsa-let-7i:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.20E-27 2.23E-23 5.41E-26 4.95E-25 87 1947 "BIRC6,NYNRIN,UVSSA,ZNF784,NCOA1,STARD13,CAST,PCDH9,CDK18,RGSL1,CCDC122,CFAP54,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,THTPA,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,TRAPPC13,PCBD2,FCAR,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FLT1,FTLP10,DDX51,UFM1,SLC30A6,SCYL2,THADA,ZNF605,POTEM,NMNAT2,ATP8A2,NPAS3,MRPS27,RBKS,MCCC2,LRCH1,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,RAB2B,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,LMLN,FIP1L1,KIF3C,DIAPH3,EP400P1,LMNB1" MicroRNA hsa-miR-567:mirSVR_highEffct hsa-miR-567:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.44E-27 2.36E-23 5.71E-26 5.23E-25 65 1093 "MDM4,KIAA1211,COG6,APAF1,ATP1A2,CCNA1,CAMK4,PDGFRA,MRPL57,CFAP54,STRN3,UBXN2A,BIVM,TBC1D4,PARPBP,DNMT3A,EGLN3,RASA1,DTD2,PACRGL,RNASEL,MBNL2,MARVELD2,BORA,SAP18,CLIP1,TRAPPC13,FCGR3A,FCGR3B,FNIP1,POLK,SUCO,FLT1,UFM1,CCDC88A,ZNF605,MRPS14,CYP1B1-AS1,GABRA2,PDS5B,HSPH1,IKBIP,PCDH17,MIMT1,PSME4,ATP11A,ADAM17,CRB1,RASSF6,TMPO,HEXB,ADAMTS19,TENT2,ZNF140,ANKS1B,CHPT1,LMLN,FIP1L1,KIF2A,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,AXDND1" MicroRNA hsa-miR-3117:mirSVR_lowEffct hsa-miR-3117:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.77E-27 2.54E-23 6.11E-26 5.60E-25 63 1025 "MSH2,SLC4A4,ZNF542P,PPP1R12B,CD84,ARHGEF7,NOVA1,CD1D,DCLK1,XPR1,CHD1,PFKFB2,PIGR,GNPTAB,KLHL3,PTPRC,OCIAD1,PTPRH,GNPDA2,B3GLCT,ARGLU1,AASDH,DTD2,RGS4,MEMO1,PACRGL,RNASEL,RNF4,EIF2B1,DHRS2,FAM172A,DRAM1,SUCO,SDC1,TMEM175,SLC34A2,FBXO11,ARHGEF40,CCDC88A,SLC12A2,N4BP2,MEGF10,GABRA2,PDS5B,KDM5B,NPAS3,BRD8,ZNF544,SCFD1,METAP2,ANO4,ARHGEF28,TEP1,CRB1,ACTR6,RIMBP2,ATP6V0A2,HSD17B4,ZNF470,ZMYM2,ZBTB41,LHX9,FIP1L1" MicroRNA hsa-miR-150:mirSVR_highEffct hsa-miR-150:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.03E-27 2.68E-23 6.44E-26 5.89E-25 56 796 "LRRC43,MDM4,TBC1D14,APC,BLZF1,PPP1R12B,CD84,MPZL1,CAST,SNTG2,PCCA,PCSK1,GLT1D1,PIWIL1,ZNF595,ATAD2B,THAP6,AKAP6,HEATR5A,EPGN,FCRL5,SREK1,FBXL5,PTPRH,WDR1,TSEN15,RNF219,REST,RGS12,RNASEL,BORA,ETF1,UTP15,LRRN2,NBEA,NUBPL,SLC8A1,TADA1,GABRB1,KDM5B,DRC1,IKBIP,SULT1E1,PPARGC1A,ARHGEF28,DOCK9,TDG,RNF17,HEXB,KLF12,HSP90B1,TMEM174,CCDC169,PLB1,GALP,RMST" MicroRNA hsa-miR-1246:mirSVR_lowEffct hsa-miR-1246:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.14E-27 2.73E-23 6.55E-26 6.00E-25 79 1623 "TMEM132B,WDR35,RGS5,CDKL4,DDX55,ASTN1,ATP1A2,SLC4A4,ATP2B4,CD84,CACNA1E,CD1E,PCK2,FAM177A1,PDE4D,PDGFRA,ITGBL1,CFAP54,SMIM14,THAP6,STRN3,SNCAIP,VCAN,ITSN2,DNM3,FCRL2,DCAF8,ZFYVE16,KLHL3,TBC1D4,RABGAP1L,RNF219,ATG10,TMEM33,PACRGL,RNASEL,LATS2,RNF4,DRAM1,CWC27,GORAB,RELL1,PIBF1,HSD17B7,FTLP10,MBIP,SLC30A6,C1orf112,MYO16,GABRA2,UHRF1BP1L,IQGAP2,ERAP1,NFASC,ANKLE2,ACSL6,ARHGEF28,DOCK9,TDG,RNF17,LINC01551,RIMBP2,ADAMTS19,ARHGAP30,TECRL,WDR36,STARD4,DCP2,ZNF10,ZNF84,ANKS1B,ZMYM2,ZBTB41,LHX9,CHPT1,RNASE11,LINC00442,LIG4,SPATA13" MicroRNA hsa-miR-636:mirSVR_lowEffct hsa-miR-636:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.66E-27 3.54E-23 8.47E-26 7.76E-25 77 1550 "COG6,ULK1,SNX24,RGS5,FBRSL1,STXBP6,FCRL3,NFATC4,ARHGEF7,SLC5A6,NOVA1,SCARB1,DCLK1,CFL2,WDFY2,NRXN1,POLN,THAP6,COPA,HEATR5A,SNCAIP,CEP135,SPATA18,PTGS2,DHX9,PARPBP,RNF219,B3GLCT,ATG10,RASA1,RGS12,NTN4,LRPPRC,RNASEL,LGR6,CWC27,PCBD2,GORAB,MROH9,SUPT20H,FBXO11,CCDC88A,ZNF605,SLC12A2,CHFR,PUS1,CYP1B1-AS1,GABRA2,KIF21B,JPH4,CENPJ,UHRF1BP1L,DRC1,LRCH1,IKBIP,SULT1E1,PSME4,ADGRA3,GPR12,TCF7,GPR161,BAZ1A,ACTR6,UBE2K,GUF1,FCRL6,IL6ST,PLB1,ANKS1B,TMEM178A,KCNN2,KIF2A,TTC41P,RMST,AXDND1,LMNB1,LOX" MicroRNA hsa-miR-1226*:mirSVR_lowEffct hsa-miR-1226*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.87E-27 3.65E-23 8.72E-26 7.98E-25 87 1961 "TMEM132B,ADD1,EP400,DHX37,FBRSL1,CENPBD1P1,NLRP4,ATP4B,PPP1R12B,BCL2L2,CD84,NFATC4,AP1G2,CAST,RILPL1,DCLK1,PCSK1,CDK18,PDE4D,PFKFB2,ZNF595,PIGR,ATAD2B,PITX1,POLN,THAP6,POLE,PREPL,LACC1,DCAF8,IFT172,PIGG,SLC35F6,PPP2R3C,RASA1,OGFOD2,RGS12,POLR1D,CRYL1,RNF4,MPHOSPH9,DHRS2,STX2,ZNF219,DRAM1,ARSK,MAEA,PCGF3,CLIP1,PCBD2,TOMM40L,LRRN2,FOXO1,HSD17B7,FTLP10,BRMS1L,GFM2,SLC8A1,TADA1,ZNF605,WDCP,C1orf112,CIDEB,KDM5B,TMEM183A,ERAP1,OXGR1,KDM3B,NFASC,MCCC2,LRCH1,CNTN2,ADGRL3,TDG,CRB1,AP4S1,GTF3C2,PAPPA2,WDR36,NSD2,FCRL6,IRF1,PGAM5,KCNN2,KIR3DL2,LCP1,LMNB1" MicroRNA hsa-miR-3180-5p:mirSVR_highEffct hsa-miR-3180-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.33E-27 3.90E-23 9.26E-26 8.48E-25 75 1474 "MAP1B,TMEM132B,CUL4A,AACS,NCOA1,NFATC4,NOVA1,CDKL2,TAF1B,CAST,FAM177A1,CDK17,PDE4D,WDFY2,NRXN1,LINC01085,SNX6,ATAD2B,UGT2B28,PTPRVP,THAP6,FAM163A,FCRL5,DCAF8,ZFYVE16,SPATA18,COG3,PTGS2,NUDT12,TINF2,SACS,ARGLU1,EIF2B1,MARVELD2,STX2,ABCA11P,F10,ELOVL7,USP44,TOMM40L,POLK,SDC1,MROH9,NBEA,NUBPL,CCDC88A,SLC12A2,WDCP,CHFR,PDS5B,EAPP,IQGAP2,MRPS27,MCCC2,ANKLE2,ERBIN,UTP20,ADAM17,PPIP5K2,ANO4,RIPK3,KHNYN,RNF17,CRB1,AP4S1,TMPO,TXK,SLAIN1,HTR2A,KIF2A,TTC7A,ZDHHC20,CDK2AP1,MICU2,SPATA13" MicroRNA hsa-miR-657:mirSVR_lowEffct hsa-miR-657:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.33E-27 3.90E-23 9.26E-26 8.48E-25 75 1474 "MAP1B,MCC,BIRC6,SEMA6A,MSH2,BLZF1,ASCL1,ASTN1,ATP1A2,SLC4A4,ZNF542P,CD84,ARHGEF7,BTF3,MORN2,PDGFRA,CFL2,PFKFB2,ITGBL1,NRXN1,THAP6,STRN3,EPGN,TTC37,PRKD1,MATR3,SPATA18,CEP350,KLHL3,RABGAP1L,RAN,AASDH,DTD2,SLC9C2,POLR1D,CRYL1,NTN4,SNORA53,FCAR,UTP15,TNFRSF19,PIBF1,SUCO,MROH9,HSD17B7,STAB2,SUPT20H,VEZT,FBXO11,NLRP2,THADA,SF3B6,EFR3B,UGGT2,MYO16,MRPS27,KLHL20,MIMT1,COMMD6,ZBTB37,RIPK3,AP4S1,HEXB,TPO,GUF1,SLAIN1,DCP2,LHX9,ANKDD1B,KIF3C,KIT,DNAH10,AXDND1,IFT88,LTA4H" MicroRNA hsa-miR-4272:mirSVR_highEffct hsa-miR-4272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.27E-27 4.40E-23 1.04E-25 9.55E-25 71 1324 "MAP1B,NLN,WDR35,APC,DDX55,BLZF1,ATP4B,ODC1,LDB2,ZNF664,PCK2,ZMYM5,RGSL1,CFL2,CHD1,ZNF595,SLC25A3,ATAD2B,THAP6,STRN3,RCHY1,GNPTAB,ZFYVE16,SPATA18,SREK1,CEP120,OCIAD1,RABGAP1L,PPP2R3C,EGLN3,RASA1,ARGLU1,SMC6,TXNDC15,CLIP1,NDUFAF7,N4BP2L2,POLK,SUCO,TM9SF1,UFM1,THADA,YPEL5,LIMCH1,PDS5B,NAAA,TMEM183A,SRP54,MCCC2,NMU,COMMD6,GJA3,PPIP5K2,METAP2,ADGRL3,DOCK9,SNRNP35,COP1,TDG,NT5C1B,MAEL,HSP90B1,UBE2K,SLAIN1,YTHDC2,ZNF10,ZNF26,ZNF470,FAM151B,KCNN2,DIAPH3" MicroRNA hsa-miR-3154:mirSVR_highEffct hsa-miR-3154:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-27 4.59E-23 1.09E-25 9.93E-25 61 968 "BIRC6,NYNRIN,NCOA1,KCTD12,CD84,NEDD8,ARHGEF7,PCDH9,NRXN1,ADGRF3,PM20D1,CLOCK,DCAF8,COG3,OCIAD1,RABGAP1L,DTD2,RGS4,MEMO1,RNASEL,UGT2A3,ZNF219,SAP18,PCGF3,RELL1,PIBF1,FMO1,FTLP10,NBEA,MBIP,IVNS1ABP,CCDC88A,LIMCH1,JPH4,TMEM183A,ERAP1,SRP54,MCCC2,CFHR4,ZBTB37,LINC02393,GOLGA3,EML4,NCSTN,FCRLA,AP4S1,ACTR6,RAB2B,TMPO,TNR,NPL,KLF12,GPN1,STARD4,MZF1,SPTSSA,FAM49A,KIF3C,KIR2DL4,RMST,PABPN1" MicroRNA hsa-miR-509-3p:mirSVR_lowEffct hsa-miR-509-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.20E-27 4.89E-23 1.15E-25 1.06E-24 66 1143 "LRRC43,MDM4,ANKRD34B,TBC1D14,RGS5,FAM193A,ASCL1,SLC4A4,STARD13,NOVA1,CAST,SNTG2,PCCA,DCLK1,PCSK1,RGSL1,GPR180,SNX6,ATAD2B,PKP1,THAP6,IL20,CTSG,MATR3,FBXL5,NUDT12,PTPRH,PXMP2,WDR1,POLR1D,GUSBP3,PACRGL,MBNL2,LGR6,ARSK,STK32B,FCGR2B,PIBF1,FLT1,FBXO11,THADA,SLC22A4,YPEL5,LIMCH1,PDS5B,ATP8A2,CMPK2,RBKS,LILRB1,PPARGC1A,STRN,ADGRL3,ARHGEF28,KHNYN,CRB1,RASSF6,TMPO,TMEM174,ZNF876P,WDR36,JCHAIN,ANKS1B,IRF1,ZBTB41,FIP1L1,SPRYD7" MicroRNA hsa-miR-4276:mirSVR_lowEffct hsa-miR-4276:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.98E-27 5.31E-23 1.25E-25 1.14E-24 85 1887 "RALGAPA1,MAP1B,MDM4,ATP6V1G3,COG6,BLZF1,ATP12A,NLRP4,ATP2B4,KCTD12,NOVA1,CBLN3,SYT2,UHMK1,PCCA,CDK17,PDGFRA,CHD1,PFKFB2,ITGBL1,PIGR,LINC01085,JAKMIP1,HOMER1,C1orf116,AKAP6,STRN3,FAM163A,ITSN2,DNM3,UBXN2A,FCRL5,DCAF8,SNX17,PTGS2,CEP350,NUDT12,COCH,PTPRH,PXMP2,WDR1,PARPBP,C14orf119,RNF219,SLC9C2,RNASEL,TXNDC15,TBC1D19,ARSK,SH3YL1,TRAPPC13,FCGR3B,SUCO,FLT1,SUPT20H,ALKAL2,IVNS1ABP,ZNF605,DCAF11,MYO16,MEGF10,KDM5B,RAPGEF6,IQGAP2,LPIN1,PPARGC1A,MAST4,ADAM17,LILRB4,KMT5A,DOCK9,AP4S1,HAL,HMGCR,TMEM174,WDR36,YTHDC2,ZNF26,SELENOI,IRF1,ZBTB41,CHPT1,KCNJ9,LMNB1,IFT88" MicroRNA hsa-miR-542-3p:mirSVR_highEffct hsa-miR-542-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.00E-26 5.33E-23 1.25E-25 1.15E-24 59 904 "RALGAPA1,MDM4,KIAA1211,WDR35,UVSSA,KCTD12,ATP7B,BTF3,SLC5A6,NOVA1,PCCA,PIGR,PIK3C2B,HECTD1,AKAP6,STRN3,COPA,CSNK1G3,FCRL5,IFT172,SNX17,COG3,PTGS2,SUPT7L,PPP2R3C,FAM129A,CLIP4,EFNA5,TRAPPC13,PIBF1,SUCO,FLT3,ALKAL2,NUBPL,UFM1,SLC30A6,SLC8A1,SLC12A2,C1orf112,YPEL5,CENPJ,TMEM183A,CD244,IKBIP,ZBTB37,UTP20,METAP2,RIPK3,DOCK9,TDG,TEP1,LINC01551,NPL,ADAMTS19,WDR36,CENPH,KIF3C,EEF1AKMT1,SKA3" MicroRNA hsa-miR-26a-5p:TargetScan hsa-miR-26a-5p TargetScan 1.08E-26 5.75E-23 1.34E-25 1.23E-24 54 746 "ABL2,MAP1B,MCC,EP400,APC,ATP1A2,NOVA1,DCLK1,PDE4D,CHD1,PFKFB2,ATAD2B,HOMER1,FAM169A,MATR3,PTGS2,DMXL1,CEP350,NOP9,SACS,G3BP2,DNMT3A,RB1,REST,RGS4,MEMO1,NTN4,SBNO1,FAM172A,DRAM1,MAEA,ETF1,FNIP1,FBXO11,G2E3,CHFR,KIF21B,RAPGEF6,LRCH1,ADAM17,METAP2,GOLGA3,GPR12,GRSF1,GPR161,GTF3C2,ADAMTS19,HTR2A,IGF1,ANKS1B,LMLN,LETM1,NUAK2,CDK2AP1" MicroRNA hsa-miR-26b-5p:TargetScan hsa-miR-26b-5p TargetScan 1.08E-26 5.75E-23 1.34E-25 1.23E-24 54 746 "ABL2,MAP1B,MCC,EP400,APC,ATP1A2,NOVA1,DCLK1,PDE4D,CHD1,PFKFB2,ATAD2B,HOMER1,FAM169A,MATR3,PTGS2,DMXL1,CEP350,NOP9,SACS,G3BP2,DNMT3A,RB1,REST,RGS4,MEMO1,NTN4,SBNO1,FAM172A,DRAM1,MAEA,ETF1,FNIP1,FBXO11,G2E3,CHFR,KIF21B,RAPGEF6,LRCH1,ADAM17,METAP2,GOLGA3,GPR12,GRSF1,GPR161,GTF3C2,ADAMTS19,HTR2A,IGF1,ANKS1B,LMLN,LETM1,NUAK2,CDK2AP1" MicroRNA hsa-miR-510:mirSVR_lowEffct hsa-miR-510:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-26 6.11E-23 1.42E-25 1.30E-24 84 1849 "MAP1B,MDM4,COG6,SEMA6A,EP400,ARL1,ASCL1,ATP12A,MYBPC1,NFATC4,CCNA1,ADGRD1,NOVA1,CBLN3,CAST,UHMK1,SNTG2,PCSK1,CDK18,PDE6B,MRPL57,POLN,FAM163A,EPGN,NGDN,CSNK1G3,ITSN2,MPHOSPH8,EIF2AK2,DCAF8,LOC439933,CEP350,F11R,GNPDA2,WDR1,PARPBP,C14orf119,EGLN3,AASDH,TMEM33,ZNF419,RNASEL,GRTP1,UGT2A3,SNORA53,ELK3,DHRS2,FAM172A,ARSK,SAP18,PCGF3,PCBD2,FCAR,FCGR2B,SDC1,SELP,VEZT,SLC30A6,THADA,ARHGEF40,CCDC88A,POTEM,FSHR,ACIN1,GABRB1,PDS5B,NMNAT2,NAAA,EAPP,ZNF274,NFASC,PPARGC1A,KMT5C,DOCK9,RNF212,ZBTB49,UBE2K,TECRL,UGT2B7,TDRD3,LETM1,SPRYD7,TTC7A,AXDND1" MicroRNA hsa-miR-146b-3p:mirSVR_lowEffct hsa-miR-146b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-26 6.12E-23 1.42E-25 1.30E-24 74 1446 "MCC,KIAA1211,ZNF784,NCOA1,ASTN1,NFATC4,RILPL1,LDB2,SNTG2,CDK7,PDGFRA,GLT1D1,PDE6B,PFKFB2,ZNF595,TSTD1,LINC01085,PIK3C2B,PKP1,NCR1,GNPTAB,NCOR2,CSNK1G3,ITSN2,CEP135,UBXN2A,FCRL5,DCAF8,LOC439933,SLC35F6,ZNF329,OGFOD2,IPO4,DTD2,RGS12,ZNF219,ARSK,ADGRV1,TOMM40L,SPON2,PIBF1,SUPT20H,RUBCNL,G2E3,ZNF605,PKD2L2,POTEM,TMEM132D,NPAS3,MRPS27,NFASC,ERBIN,NMU,ZNF544,UTP20,TDG,FCRLA,CRB1,SLC7A8,MAEL,ADAMTS19,ARHGAP30,HMGCR,STARD4,YTHDC2,JCHAIN,SPTSSA,ZBED3-AS1,KCNN2,FIP1L1,KIF3C,LAD1,RMST,PABPN1" MicroRNA hsa-miR-519b-3p:mirSVR_highEffct hsa-miR-519b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.28E-26 6.82E-23 1.58E-25 1.45E-24 73 1410 "MAP1B,MATN3,MCC,MDM4,BIRC6,EP400,ARL1,ATP12A,SLC4A4,ZNF542P,LINC02347,ADGRD1,NRL,RILPL1,FCHO2,SNTG2,PDGFRA,CFL2,JAKMIP1,TAPT1,RCHY1,FAM53A,GNPTAB,PREPL,ITSN2,UBXN2A,DCAF8,ZFYVE16,SNX17,PIGG,FBXL5,CEP120,SACS,EGLN3,FAM129A,LAP3,CLIP4,NTN4,ELK3,ZNF671,DLEU1,N4BP2L2,PIBF1,FOXG1,FOXO1,NBEA,BRMS1L,UFM1,CCDC88A,SNRPF,MYT1L,KDM5B,ERAP1,CMPK2,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,NPFFR2,PPIP5K2,C5orf56,UBC,SLAIN1,NSD2,ANKS1B,LHX9,FAM151B,KCNN2,CAB39L,RMST,LIG4,CDK2AP1" MicroRNA hsa-miR-3160:mirSVR_highEffct hsa-miR-3160:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-26 7.07E-23 1.64E-25 1.50E-24 59 909 "ACOX3,KIAA1211,SLAMF6,UVSSA,KCTD12,CDKL2,PCDH9,RGSL1,PDE4D,CFL2,PIWIL1,ZNF595,WDFY2,HECTD1,TAPT1,SYCP3,ITSN2,DNM3,CEP350,TSEN15,ATG10,RB1,FAM228A,GUSBP3,RNASE2,DHRS2,ETF1,DLEU1,TLR6,FCGR2B,FCGR3A,FCGR3B,FGF9,PIBF1,SLC34A2,CGREF1,YPEL5,PUS1,GABRA2,GABRB1,NAAA,ERAP1,MRPS27,RBKS,EML4,RNF212,TDG,MAEL,ADAMTS19,TMEM174,ZNF550,NLRP8,VRK2,YTHDC2,JCHAIN,GALP,ANKS1B,LINC01913,LTA4H" MicroRNA hsa-miR-3137:mirSVR_lowEffct hsa-miR-3137:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-26 7.43E-23 1.72E-25 1.57E-24 73 1412 "MDM4,COG6,HOMEZ,BLZF1,STXBP6,NCOA1,NRL,CDKL2,LDB2,FCGR2C,ZNF664,CDK17,PDE4D,PFKFB2,ZNF595,CFAP54,CFAP45,PTPRVP,THAP6,STRN3,CLOCK,SNCAIP,CSNK1G3,KIAA0040,SNX17,COG3,CEP350,RABGAP1L,NR1I3,FAM129A,B3GLCT,ARGLU1,MEMO1,KLHL12,MARVELD2,FAM172A,DRAM1,EFS,CWC27,DNAJC27,F10,POLK,FLT3,TM9SF1,TMEM175,STPG4,ARHGEF40,C1orf112,EFR3B,KDM5B,IQGAP2,GC,IKBIP,SULT1E1,ADAM17,RNF17,AP4S1,RAB2B,TMPO,RIMBP2,MAEL,HMGCR,TECRL,FCRL6,ZNF26,KCNT2,ZNF324B,LHX9,CHPT1,LINC00442,FAM71C,NUAK2,ZDHHC20" MicroRNA hsa-let-7g:mirSVR_lowEffct hsa-let-7g:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-26 7.57E-23 1.75E-25 1.60E-24 85 1897 "BIRC6,NYNRIN,UVSSA,ZNF784,NCOA1,STARD13,CAST,PCDH9,CDK18,RGSL1,GLT1D1,PFKFB2,PIK3C2B,ATAD2B,PKP1,HOMER1,AKAP6,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,TRAPPC13,PCBD2,FCAR,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,DDX51,UFM1,SLC30A6,SCYL2,THADA,ZNF605,POTEM,CHFR,EFR3B,ATP8A2,NPAS3,MRPS27,RBKS,MCCC2,ANKLE2,LRCH1,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,C12orf73,PLB1,SPTSSA,ZMYM2,LMLN,FIP1L1,DIAPH3,EP400P1,LMNB1" MicroRNA hsa-miR-744*:mirSVR_lowEffct hsa-miR-744*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-26 8.24E-23 1.89E-25 1.73E-24 78 1611 "TMEM132B,ADORA1,NYNRIN,PITPNM2,DHX37,UVSSA,APBB2,DDX55,BLZF1,AACS,ATP1A2,BCL2L2,ARHGEF7,RAB29,NOVA1,MPZL1,LDB2,CD1D,SNTG2,ZNF664,PCDH9,PCSK1,RGSL1,MRPL57,POLN,THAP6,AKAP6,PREPL,SNCAIP,LACC1,TTC37,C12orf65,KIAA0040,UBXN2A,SPATA18,OCIAD1,F11R,PTPRH,G3BP2,C14orf119,DNMT3A,FAM129A,KLHL12,GP6,ARSK,SAP18,ABCA11P,PCGF3,TOMM40L,NDUFAF7,FNIP1,SUCO,FLT1,POTEM,C1orf112,DCAF11,GABRA2,PDS5B,ERAP1,SRP72,NEDD1,PSME4,CNTN2,TCF7,COP1,XPO4,RNF17,AP4S1,RAB2B,TECRL,HTR2A,NSD2,ANKS1B,DNAH10,LETM1,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-1246:mirSVR_highEffct hsa-miR-1246:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-26 8.91E-23 2.04E-25 1.87E-24 69 1265 "ADD1,ATP6V1G3,COG6,SEMA6A,HOMEZ,APC,BLZF1,STARD13,BCL2L2,ARHGEF7,LDB2,ZNF664,PCDH9,NRXN1,AKAP6,CSNK1G3,LRRTM2,CEP135,FCRL5,CEP350,OCIAD1,SLC35F6,PARPBP,EGLN3,RASA1,CLIP4,POLR1D,NTN4,SETDB2,MBNL2,TRAPPC12,SPATA9,MARVELD2,ARSK,ETF1,FMO1,THADA,CCDC88A,SLC12A2,SLC15A4,MRPS14,YPEL5,KIF21B,PDS5B,CD244,MCCC2,NPFFR2,METAP2,ADGRL3,ANO4,GPR12,GPR161,HAL,HEXB,TXK,SLAIN1,ZNF876P,VRK2,JCHAIN,ZNF470,C12orf73,IL6ST,SPTSSA,FAM151B,DIAPH3,LINC01913,FAM71C,LOX,ZNF304" MicroRNA hsa-miR-4252:mirSVR_lowEffct hsa-miR-4252:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.77E-26 9.41E-23 2.15E-25 1.97E-24 84 1861 "MDM4,ADD1,SLAMF6,ASCL1,ASTN1,ATP1A2,ATP4B,STARD13,CCNA1,DCLK1,FAM177A1,RGSL1,ZNF595,SMIM14,POLN,NCR1,STRN3,FAM163A,SNCAIP,DNM3,ZNF586,DCAF8,PIGG,COG3,FBXL5,KLHL3,TBC1D4,GNPDA2,C14orf119,DNMT3A,RAN,ZNF329,RGS4,RGS12,ZNF419,PACRGL,RNASEL,MARVELD2,DHRS2,TBC1D19,DEPDC4,DRAM1,ARSK,ADGRV1,USP44,FCAR,UTP15,FCGR3B,HSD17B7,FBXO11,SLC30A6,STPG4,THADA,ARHGEF40,PKD2L2,TMEM132D,MYO16,KIF21B,UHRF1BP1L,ERAP1,MRPS27,MCCC2,LILRB1,SULT1E1,UTP20,PPIP5K2,ADGRL3,ADGRA3,ACSL6,STON1,RNF17,AP4S1,RAB2B,HEXB,RXFP2,PAPPA2,WDR36,IL25,NSD2,PGAM5,FAM151B,KIF3C,LETM1,ZDHHC20" MicroRNA hsa-miR-548s:mirSVR_lowEffct hsa-miR-548s:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-26 1.00E-22 2.29E-25 2.09E-24 81 1738 "LRRC43,NYNRIN,CUL4A,MCFD2,CENPBD1P1,SLC4A4,BCL2L2,CBLN3,PCDH9,FAM177A1,GLT1D1,VIT,MRPL57,CPNE6,TM9SF2,ATAD2B,C1orf116,TAPT1,MPHOSPH8,FCRL5,EIF2AK2,ZNF586,IFT172,SNX17,PIGG,COG3,FBXL5,RABGAP1L,DNMT3A,AASDH,RGS4,POLR1D,LRPPRC,TXNDC15,MBNL2,MARVELD2,TCTN2,STK32B,ADGRV1,SLC22A17,PCBD2,FCAR,FCGR3A,RASA3,SH3BP2,G2E3,SLC30A6,CGREF1,C1orf112,EFR3B,CYP1B1-AS1,PDS5B,RAPGEF6,TMEM183A,HSPH1,DRC1,LILRB1,LPIN1,PPARGC1A,UTP20,LINC02393,ANO4,DOCK9,RNF212,XPO4,COX18,CRB1,MAEL,ADAMTS19,ZNF550,RXFP2,ZNF876P,IGF1,LINC00272,PGAM5,ZBED3-AS1,DNAH10,LINC01913,LINC00442,AXDND1,IFT88" MicroRNA hsa-miR-216a:mirSVR_highEffct hsa-miR-216a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.08E-26 1.11E-22 2.51E-25 2.30E-24 72 1383 "ANKRD34B,CUL4A,ASCL1,NCOA1,PCCA,PCK2,CFL2,VIT,NUP37,BOD1L1,THAP6,VCAN,C12orf65,MATR3,PSME1,PIGG,SREK1,DMXL1,PTPRH,C14orf119,NR1I3,RB1,TMEM161B,FAM228A,RGS12,CLIP4,RNASEL,MBNL2,DCUN1D2,UGT2A3,ELF1,ETF1,ADGRV1,NDUFAF7,GORAB,FNIP1,PIBF1,FOXO1,RUBCNL,IVNS1ABP,PKD2L2,N4BP2,NR5A2,MEGF10,GABRA2,GABRB1,KIF21B,ZNF274,OXGR1,CMPK2,NEDD1,IKBIP,PPARGC1A,BRD8,MAST4,TMED2,METAP2,ADGRL3,EML4,CRB1,AP4S1,RASSF6,GUF1,TENT2,HTR2A,NSD2,ANKS1B,ZBED3-AS1,CHPT1,FIP1L1,RNASE11,RILPL2" MicroRNA hsa-miR-1914:mirSVR_lowEffct hsa-miR-1914:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.08E-26 1.11E-22 2.51E-25 2.30E-24 72 1383 "NDRG2,TMEM132B,EP400,RGS5,ARHGAP5,ARL1,NCOA1,ASTN1,CENPBD1P1,BCL2L2,ARHGEF7,AP1G2,AMDHD1,CDK18,HECTD1,THAP6,TAPT1,VCAN,LRRTM2,FAM169A,DNM3,SPATA18,COG3,KLHL3,RABGAP1L,RNF31,OGFOD2,FAM228A,PACRGL,RNASEL,TXNDC15,GRTP1,RNF4,ZNF219,ADGRV1,ELOVL7,PCBD2,SUPT20H,RUBCNL,SLC34A2,G2E3,TADA1,ZNF605,SLC12A2,WDCP,SLC22A4,LIMCH1,FAM114A1,NMNAT2,ZNF274,CD244,ERBIN,ATP11A,TCF7,DOCK9,KHNYN,FCRLA,NT5C1B,AP4S1,HSP90B1,HPCAL1,IL25,DCP2,YTHDC2,JCHAIN,ANKS1B,LHX9,KCNJ9,ANKDD1B,KIF2A,RMST,LMNB1" MicroRNA hsa-miR-4318:mirSVR_lowEffct hsa-miR-4318:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.09E-26 1.11E-22 2.51E-25 2.30E-24 79 1659 "ADD1,ATP6V1G3,NYNRIN,RGS5,MCFD2,MSH2,AACS,CENPBD1P1,CCDC181,ATP7B,BCL2L2,BTF3,SLC5A6,NOVA1,CHAMP1,PCCA,PCK2,CDK18,CENPC,CHD1,BOD1L1,POLN,PTPRVP,THAP6,VCAN,DNM3,KIAA0040,FCRL5,CTSG,NOS1AP,GLT8D2,DDX59,ZNF586,SPATA18,DCT,RABGAP1L,C12orf42,NR1I3,DNMT3A,FAM129A,B3GLCT,FAM228A,CLIP4,NTN4,LRPPRC,MAEA,TMEM156,POLK,FTLP10,SUPT20H,ARHGEF40,CCDC88A,C1orf112,MEGF10,NMNAT2,RAPGEF6,CENPJ,LRCH1,PCDH17,COMMD6,MAST4,KMT5A,NCSTN,TMPO,RIMBP2,TECRL,ZNF876P,YTHDC2,IGF1,JCHAIN,SELENOI,IL6ST,LHX9,FIP1L1,KIR2DL4,KIR2DS4,KIR3DL1,LAD1,ZNF304" MicroRNA hsa-miR-584:mirSVR_lowEffct hsa-miR-584:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-26 1.15E-22 2.59E-25 2.37E-24 74 1461 "MAP1B,TMEM132B,WDR35,MCFD2,MSH2,ARL1,PPP1R12B,MORN2,FAM177A1,XPR1,PDE4D,CFL2,PGGT1B,ITGBL1,NRXN1,THAP6,PM20D1,SNCAIP,LACC1,IL20,SNX17,CEP350,KLHL3,PTPRC,RABGAP1L,GNPDA2,C14orf119,NR1H4,CLIP4,MEMO1,EFNA5,ELK3,STX2,GP6,DEPDC4,ARSK,MAEA,ABCA11P,ADGRV1,TMEM129,FNIP1,POLK,FBXO11,NBEA,SCYL2,SLC15A4,MEGF10,RAPGEF6,GC,NEDD1,RNF17,ZBTB49,HAL,ADAMTS19,RXFP2,ZNF876P,DCP2,ZNF10,ZNF26,TADA2B,ZNF84,SELENOI,IL6ST,IRF1,ZBTB41,LHX9,FAM151B,TDRD3,CAB39L,RPGRIP1,FAM71C,SPRYD7,LMNB1,LOX" MicroRNA hsa-miR-506:mirSVR_highEffct hsa-miR-506:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.37E-26 1.26E-22 2.84E-25 2.60E-24 64 1091 "BIRC6,NYNRIN,SEMA6A,SNX24,UVSSA,CDKL4,CCNA1,FCHO2,SLC5A8,PCDH9,FAM177A1,DHRS1,COLEC11,SNX6,ATAD2B,AKAP6,COPA,CLOCK,SNCAIP,VCAN,ITSN2,PRKD1,ZNF586,SREK1,FBXL5,OCIAD1,G3BP2,RGS12,PACRGL,ELK3,FAM172A,ZNF219,SAP18,DLEU1,ADGRV1,SUCO,FMO1,G2E3,ALKAL2,ZNF605,SLC15A4,SLC22A5,ZNF667,LIMCH1,IQGAP2,MRPS27,SRP54,ANKLE2,PCDH17,GJB2,PPIP5K2,METAP2,GOLGA3,ANO4,AP4S1,HEXB,ADAMTS19,TADA2B,IRF1,FAM151B,KIF2A,DIAPH3,LINC01913,AXDND1" MicroRNA hsa-miR-3159:mirSVR_highEffct hsa-miR-3159:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-26 1.27E-22 2.86E-25 2.62E-24 63 1056 "RALGAPA1,MAP1B,ADD1,ARL1,SLC4A4,B4GALT3,CD84,CHAMP1,UHMK1,FAM177A1,GPR180,CKMT2,ITGBL1,TM9SF2,THAP6,AKAP6,RCHY1,GNPTAB,VCAN,DNM3,ZFYVE16,MATR3,NUDT12,TINF2,SACS,SMC6,RGS12,POLR1D,EIF2D,TBC1D19,ETF1,FCAR,FNIP1,TNFRSF19,POLK,SUCO,SLC8A1,MYO16,GABRB1,PDS5B,NAAA,HSPH1,SRP72,IKBIP,NPFFR2,LPIN1,PPARGC1A,GJA3,ZNF544,LINC02393,CNTN2,GPR12,RNF17,TEP1,NPL,STARD4,CCDC169,FAM151B,CHPT1,KIF2A,DIAPH3,IFT88,ZNF304" MicroRNA hsa-miR-671-5p:mirSVR_lowEffct hsa-miR-671-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-26 1.29E-22 2.90E-25 2.66E-24 79 1663 "RALGAPA1,ADD1,ACOX3,EP400,PPFIA4,BLZF1,ASCL1,AACS,CENPBD1P1,ATP1A2,SLC4A4,STARD13,MYH6,NFATC4,CAD,SCARB1,PDE4D,CPNE6,SMIM14,HECTD1,THAP6,TAPT1,RNASE9,GNPTAB,SNCAIP,CSNK1G3,KIAA0040,FCRL5,SPATA18,PIGG,DHX9,KLHL3,PTPRC,OCIAD1,RABGAP1L,DNMT3A,FAM129A,RNF31,AASDH,IPO4,SETDB2,SNORA53,MPHOSPH9,STX2,STK32B,FCAR,TOMM40L,LRRN2,STAB2,ZNF446,THADA,CGREF1,YPEL5,GABRA2,NFASC,DRC1,MIMT1,SULT1E1,ZNF544,MTUS2,ANO4,RIPK3,STON1,KMT5C,RNF17,NT5C1B,CRB1,NPL,HEXB,TPO,ADAMTS19,ARHGAP30,CCDC169,CCDC190,SDR39U1,ZBED3-AS1,FIP1L1,LCP1,AXDND1" MicroRNA hsa-miR-628-5p:mirSVR_highEffct hsa-miR-628-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-26 1.29E-22 2.90E-25 2.66E-24 57 854 "SMIM15,MDM4,BIRC6,COG6,STXBP6,ADGRD1,PNP,CAST,CHAMP1,UHMK1,CDK18,STRN3,TOGARAM2,PM20D1,EPGN,VCAN,UBXN2A,PRKD1,DDX59,DMXL1,LOC439933,B3GLCT,AASDH,RNASEL,CWC27,STK32B,DLEU1,USP44,TRAPPC13,GOLGA2P5,RUBCNL,NBEA,BRMS1L,CYP1B1-AS1,NAAA,ZBTB37,METAP2,ADGRA3,ANO4,ACSL6,RNF17,KLF12,SLAIN1,VRK2,KCNT2,IL6ST,CCDC169,ANKS1B,LHX9,ZBED3-AS1,CHPT1,TMEM178A,KIR2DL1,KIR3DL1,RMST,AXDND1,ZDHHC20" MicroRNA hsa-miR-376c:mirSVR_lowEffct hsa-miR-376c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.55E-26 1.35E-22 3.03E-25 2.77E-24 80 1705 "BIRC6,TMEM132B,SLAMF6,COG6,SNX24,RGS5,APC,MSH2,BLZF1,SLC4A4,ATP2B4,ADGRD1,CHAMP1,DCLK1,PCK2,PGGT1B,ATAD2B,HECTD1,STRN3,MPC2,FAM163A,ITSN2,FCRL5,NOS1AP,ZFYVE16,SREK1,F11R,G3BP2,PARPBP,C14orf119,NR1H4,EGLN3,FAM129A,B3GLCT,RASA1,RB1,RGS4,LAP3,TMEM33,TXNDC15,RNF4,MBNL2,ELF1,LGR6,CLIP1,PIBF1,POLK,FLT1,HSD17B7,FBXO11,NR5A2,ACIN1,MYT1L,IQGAP2,HSPH1,MRPS27,GJA3,ATP11A,ADGRA3,ANO4,GPR12,EML4,XPO4,GRSF1,CRB1,ZBTB49,AP4S1,GTF2H3,TMEM174,SLAIN1,ZNF10,ZNF84,CHPT1,FIP1L1,LINC00442,NUAK2,TTC7A,LIG4,LOX,SKA3" MicroRNA hsa-miR-378*:mirSVR_lowEffct hsa-miR-378*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.78E-26 1.48E-22 3.30E-25 3.02E-24 85 1916 "MAP1B,NLN,EP400,RGS5,MCFD2,MSH2,NCOA1,ZNF542P,ATP2B4,ATP4B,NOVA1,CACNA1E,CD1D,PAH,RFLNA,PCCA,PDE6B,PFKFB2,GPR180,HOMER1,C1orf116,EPGN,NGDN,SNCAIP,C12orf65,ITSN2,PRKD1,NOS1AP,FCRL2,ZFYVE16,OCIAD1,RABGAP1L,DHFR,PXMP2,LINC01257,SLC9C2,LAP3,CLIP4,GUSBP3,LRPPRC,EIF2D,RNASEL,LATS2,KLHL12,DHRS2,ARSK,ADGRV1,POLK,SUCO,FOXG1,FLT1,HSD17B7,TM9SF1,SLC34A2,ZNF605,SLC12A2,ZNF667,CHFR,LIMCH1,NMNAT2,NAAA,ERAP1,ATP8A2,LRCH1,LILRB1,IKBIP,PCDH17,LINC02393,RNF17,CRB1,ZBTB49,AP4S1,BAZ1A,MAEL,NSD2,ZNF26,KCNT2,ZNF84,IL6ST,TMEM178A,EP400P1,LAD1,LETM1,IFT88,SPATA13" MicroRNA hsa-let-7f:mirSVR_lowEffct hsa-let-7f:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.79E-26 1.48E-22 3.30E-25 3.02E-24 82 1790 "BIRC6,NYNRIN,ZNF784,NCOA1,STARD13,CAST,PCDH9,PCSK1,CDK18,RGSL1,CCDC122,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,ELOVL7,TRAPPC13,PCBD2,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,SH3BP2,UFM1,SCYL2,THADA,ZNF605,POTEM,EFR3B,ATP8A2,NPAS3,MRPS27,RBKS,MCCC2,ANKLE2,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,HMGCR,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1,RNASE11,LMNB1" MicroRNA hsa-miR-21*:mirSVR_lowEffct hsa-miR-21*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.83E-26 1.51E-22 3.35E-25 3.06E-24 79 1667 "RALGAPA1,MAP1B,MATN3,KIAA1211,NYNRIN,SEMA6A,STXBP6,SLC4A4,STARD13,KCTD12,NFKBIA,CACNA1E,SNTG2,CDK18,PKP1,NCR1,HOMER1,STRN3,NOS1AP,DMXL1,CEP120,PTPRC,F11R,SLC35F6,PARPBP,FAM228A,CLIP4,GUSBP3,PACRGL,MBNL2,ELF1,KLHL12,STX2,DRAM1,ABCA11P,PCGF3,PCBD2,FGF9,RELL1,POLK,SUCO,FOXO1,NUBPL,THADA,ZNF605,SLC12A2,UGGT2,MEGF10,GAK,RAPGEF6,TMEM183A,HSPH1,MCCC2,PPARGC1A,GJA3,METAP2,ADGRA3,GPR12,TDG,FCRLA,GRSF1,ZBTB49,BAZ1A,MAEL,UBE2K,TECRL,TMEM174,HPCAL1,FCRL6,ZNF26,ANKS1B,ZBED3-AS1,CHPT1,KIF2A,KIT,LINC01913,LMNB1,PABPN1,LOX" MicroRNA hsa-miR-571:mirSVR_lowEffct hsa-miR-571:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.84E-26 1.51E-22 3.35E-25 3.07E-24 71 1352 "RALGAPA1,ADD1,SLAMF6,ATP6V1G3,BLZF1,ATP12A,CD84,DAOA,CAST,AMDHD1,RILPL1,LDB2,PCK2,PCSK1,RGSL1,CFL2,ATAD2B,BOD1L1,LTB4R,PTPRVP,AKAP6,FAM163A,POU2F1,SNCAIP,GALNT9,PRKD1,FCRL5,NUDT12,C14orf119,RB1,PACRGL,EIF2B1,ELF1,LGR6,MARVELD2,STK32B,MAEA,ABCA11P,FLT1,FTLP10,VEZT,ZCCHC8,FBXO11,CCDC88A,C1orf112,MRPS14,LIMCH1,CYP1B1-AS1,NMNAT2,CENPJ,ERBIN,COX7B2,GOLGA3,ADGRA3,RNF212,SLC7A8,ZNF721,NPL,ARHGAP30,RXFP2,PAPPA2,NSD2,IGF1,TADA2B,SDR39U1,LHX9,TDRD3,ZBED3-AS1,KIT,AMTN,RMST" MicroRNA hsa-miR-516b*:mirSVR_highEffct hsa-miR-516b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-26 1.54E-22 3.40E-25 3.12E-24 57 857 "KIAA1211,DDX55,ATP1A2,STARD13,CAST,FCHO2,RGSL1,PDGFRA,CFL2,TAPT1,CSNK1G3,TTC37,ZFYVE16,PARPBP,GALNT14,RGS12,MBNL2,MPHOSPH9,MARVELD2,FCAMR,STX2,ARSK,STK32B,GMPR2,PCGF3,TNFRSF19,VEZT,G2E3,IVNS1ABP,THADA,CCDC88A,FSHR,MYT1L,RAPGEF6,EAPP,HSPH1,NFASC,LRCH1,PPIP5K2,YIPF7,GZMB,TMPO,FZD10,RIMBP2,TNR,HEXB,UBE2K,TRPC4,TMEM174,IL25,YTHDC2,ZNF26,KCNT2,KCNN2,TTC41P,AXDND1,LMNB1" MicroRNA hsa-miR-516a-3p:mirSVR_highEffct hsa-miR-516a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-26 1.54E-22 3.40E-25 3.12E-24 57 857 "KIAA1211,DDX55,ATP1A2,STARD13,CAST,FCHO2,RGSL1,PDGFRA,CFL2,TAPT1,CSNK1G3,TTC37,ZFYVE16,PARPBP,GALNT14,RGS12,MBNL2,MPHOSPH9,MARVELD2,FCAMR,STX2,ARSK,STK32B,GMPR2,PCGF3,TNFRSF19,VEZT,G2E3,IVNS1ABP,THADA,CCDC88A,FSHR,MYT1L,RAPGEF6,EAPP,HSPH1,NFASC,LRCH1,PPIP5K2,YIPF7,GZMB,TMPO,FZD10,RIMBP2,TNR,HEXB,UBE2K,TRPC4,TMEM174,IL25,YTHDC2,ZNF26,KCNT2,KCNN2,TTC41P,AXDND1,LMNB1" MicroRNA hsa-miR-134:mirSVR_lowEffct hsa-miR-134:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.91E-26 1.55E-22 3.41E-25 3.12E-24 77 1587 "BIRC6,ADD1,KIAA1211,NYNRIN,MSH2,ARL1,SLC4A4,ATP2B4,ARHGEF7,TAF1B,MPZL1,PCDH9,PCK2,PCSK1,PDE4D,GLT1D1,BOD1L1,AKAP6,FAM163A,PM20D1,EPGN,CSNK1G3,VCAN,FAM169A,DNM3,BIVM,SPATA18,COG3,LOC439933,NUDT12,COCH,TBC1D4,PARPBP,FAM129A,B3GLCT,RGS4,KIRREL1,MPHOSPH9,ZNF671,FAM81B,DLEU1,F10,TOMM40L,FNIP1,SELP,FLT1,NBEA,UFM1,CCDC88A,WDCP,C1orf112,GABRB1,PDS5B,NAAA,UHRF1BP1L,GJB6,DRC1,LILRB1,IKBIP,ZBTB37,PPARGC1A,MAST4,TBC1D1,ADGRL3,ADGRA3,ARHGEF28,GTF3C2,ARHGAP30,NLRP8,NSD2,JCHAIN,IL6ST,PLB1,LMLN,FIP1L1,LINC01913,LOX" MicroRNA hsa-miR-519a:mirSVR_highEffct hsa-miR-519a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.99E-26 1.59E-22 3.49E-25 3.20E-24 73 1430 "MAP1B,MATN3,MCC,MDM4,BIRC6,EP400,ARL1,ATP12A,SLC4A4,ZNF542P,LINC02347,ADGRD1,NRL,RILPL1,FCHO2,PDGFRA,CFL2,JAKMIP1,TAPT1,RCHY1,FAM53A,GNPTAB,PREPL,ITSN2,UBXN2A,DCAF8,ZFYVE16,SNX17,PIGG,FBXL5,CEP120,SACS,EGLN3,FAM129A,LAP3,CLIP4,NTN4,RNASEL,ELK3,ZNF671,DLEU1,N4BP2L2,PIBF1,FOXG1,FOXO1,NBEA,BRMS1L,UFM1,CCDC88A,MYT1L,KDM5B,ERAP1,CMPK2,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,NPFFR2,PPIP5K2,C5orf56,MAEL,UBC,SLAIN1,NSD2,ANKS1B,LHX9,FAM151B,KCNN2,CAB39L,RMST,LIG4,CDK2AP1" MicroRNA hsa-miR-217:mirSVR_highEffct hsa-miR-217:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.02E-26 1.61E-22 3.52E-25 3.22E-24 69 1278 "MSH2,NOVA1,CACNA1E,RILPL1,PCDH9,PKP1,BOD1L1,THAP6,HOMER1,AKAP6,MPC2,GNPTAB,POU2F1,LACC1,EIF2AK2,SPATA18,SREK1,G3BP2,RABGAP1L,SUPT7L,NR1I3,RGS12,POLR1D,PACRGL,EFNA5,MPHOSPH9,ABCA11P,ADGRV1,SLC22A17,TOMM40L,SUPT20H,SGCG,TM9SF1,FBXO11,BRMS1L,MBIP,PAICS,IVNS1ABP,ZNF605,C1orf112,MRPS14,LIMCH1,PDS5B,ATP8A2,NPAS3,CMPK2,SRP72,LRCH1,IKBIP,GJA3,BRD8,UTP20,TMED2,PPIP5K2,ADGRL3,ADGRA3,TDG,COX18,RASSF6,ZNF721,HAL,UBE2K,IL6ST,SPTSSA,ZMYM2,TMEM178A,KIF3C,FAM71C,SKA3" MicroRNA hsa-miR-2113:mirSVR_highEffct hsa-miR-2113:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-26 1.64E-22 3.59E-25 3.29E-24 65 1132 "RALGAPA1,ADD1,ANKRD34B,WDR35,UVSSA,ARHGAP5,ATP1A2,ADGRD1,CACNA1E,FCHO2,SNTG2,PCCA,PCK2,CDK17,CFAP54,HOMER1,AKAP6,STRN3,LYSMD3,CRHBP,FAM169A,ZFYVE16,SNX17,COG3,TSEN15,POLR1D,EFNA5,ETF1,SH3YL1,POLK,RUBCNL,G2E3,UFM1,CCDC88A,ZNF605,CHFR,LIMCH1,MYT1L,PDS5B,KDM3B,SRP72,DRC1,RBKS,NEDD1,LRCH1,ERBIN,KLHL20,COMMD6,MAST4,COX7B2,PPIP5K2,ADGRL3,ZBTB49,ACTR6,ADAMTS19,PAPPA2,HTR2A,STARD4,LINC00272,FAM151B,KCNN2,CAB39L,TTC41P,AXDND1,LTA4H" MicroRNA hsa-let-7a:mirSVR_lowEffct hsa-let-7a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-26 1.65E-22 3.61E-25 3.31E-24 82 1793 "BIRC6,NLN,NYNRIN,ZNF784,NCOA1,STARD13,CAST,PCDH9,CDK18,RGSL1,CCDC122,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,ELOVL7,TRAPPC13,PCBD2,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,UFM1,SCYL2,THADA,ZNF605,POTEM,EFR3B,ATP8A2,NPAS3,MRPS27,NFASC,RBKS,MCCC2,ANKLE2,LRCH1,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1,RNASE11,LMNB1" MicroRNA hsa-miR-519b-3p:mirSVR_lowEffct hsa-miR-519b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.57E-26 1.90E-22 4.13E-25 3.78E-24 80 1714 "ADD1,WDR35,ARHGAP5,NCOA1,ATP4B,KCTD12,MYH6,ATP7B,BCL2L2,NFATC4,NFKBIA,DAOA,CACNA1E,CDKL2,PDE4D,CHD1,PFKFB2,ATAD2B,THAP6,THTPA,HEATR5A,FAM169A,DNM3,NOS1AP,EPS8L1,SREK1,COG3,CEP350,OCIAD1,G3BP2,GNPDA2,WDR1,RNF219,RB1,MEMO1,LRPPRC,EFNA5,LATS2,MPHOSPH9,CLIP1,IRF9,FGF9,TNFRSF19,POLK,SDC1,PEAR1,FBXO11,NUBPL,SLC8A1,SLC12A2,SLC22A5,ZNF667,GABRB1,KIF21B,ZNF274,UHRF1BP1L,NFASC,TBC1D1,INSM2,ATP11A,MTUS2,ADGRA3,XPO4,RNF17,CRB1,RIMBP2,ATP6V0A2,TENT2,IGF1,KCNT2,ZNF140,ZBTB41,ZBED3-AS1,DIAPH3,KIT,LINC01913,LINC00442,TTC7A,LMNB1,ZNF304" MicroRNA hsa-miR-514:mirSVR_lowEffct hsa-miR-514:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.70E-26 1.97E-22 4.28E-25 3.92E-24 80 1715 "RALGAPA1,BIRC6,KIAA1211,WDR35,SEMA6A,ARL1,NEDD8,NOVA1,CHAMP1,CD1D,RFLNA,SLC5A8,PDE4D,PDGFRA,CHD1,PIK3C2B,C1orf116,AKAP6,FAM163A,SNCAIP,VCAN,CEP135,PRKD1,FCRL5,DCAF8,MATR3,PTGS2,FBXL5,LOC439933,F11R,FAM129A,RASA1,ZNF329,EIF2B1,ELF1,LGR6,ZNF671,ARSK,TRAPPC13,STAB2,SUPT20H,BRMS1L,ZNF446,TADA1,TMEM132D,MEGF10,MYT1L,PDS5B,NAAA,ATP8A2,SRP54,SRP72,ANKLE2,ERBIN,LPIN1,ZNF544,ACSL6,TFDP1,CRB1,TGFBI,ZBTB49,ADAMTS19,UGT2B7,ZNF876P,TENT2,VRK2,WDR36,ZNF10,KCNT2,ZMYM2,ZBTB41,PGAM5,LHX9,KIR2DS4,LETM1,RMST,IFT88,PABPN1,MICU2,ZNF304" MicroRNA hsa-miR-649:mirSVR_lowEffct hsa-miR-649:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.84E-26 2.04E-22 4.43E-25 4.05E-24 74 1475 "ABL2,NYNRIN,SEMA6A,SNX24,APAF1,ARL1,ZNF542P,ARHGEF7,CDKL2,AMDHD1,FCGR2C,FAM177A1,PCSK1,CDK17,PDGFRA,CHD1,CCDC122,BOD1L1,ADGRF3,PTPRVP,CLOCK,LACC1,VCAN,PRKD1,ZNF586,SREK1,NUDT12,GNPDA2,PXMP2,PARPBP,DNMT3A,ZNF419,LRPPRC,EIF2D,EFNA5,ELF1,MARVELD2,FAM172A,DEPDC4,ADGRV1,USP44,TOMM40L,N4BP2L2,PIBF1,POLK,FOXG1,VEZT,UFM1,SLC12A2,POTEM,SLC22A4,YPEL5,ACIN1,GABRB1,NMNAT2,RAPGEF6,GJB6,NFASC,PCDH17,PPARGC1A,ATP11A,METAP2,TCF7,STON1,DOCK9,ZBTB49,GUF1,RXFP2,YTHDC2,ZNF10,ZMYM2,FAM49A,RNASE11,IFT88" MicroRNA hsa-miR-3198:mirSVR_lowEffct hsa-miR-3198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.63E-26 2.46E-22 5.33E-25 4.88E-24 80 1721 "MCC,MDM4,SLAMF6,NYNRIN,MCFD2,MSH2,ARHGAP5,FAM193A,ATP1A2,CD84,NOVA1,CAD,CDKL2,FCGR2C,PAH,FAM177A1,XPR1,CCDC122,WDFY2,THAP6,AKAP6,FAM163A,COPA,RCHY1,PREPL,TTC37,LRRTM2,FAM169A,BIVM,PSME1,GNPDA2,SUPT7L,LINC01257,PARPBP,B3GLCT,ZNF329,RGS4,LRPPRC,EFNA5,TXNDC15,MBNL2,DRAM1,ADGRV1,F7,FCAR,TNFRSF19,POLK,FTLP10,SUPT20H,VEZT,G2E3,SLC30A6,ARHGEF40,DCAF11,NMNAT2,HSPH1,OXGR1,CMPK2,LRCH1,LILRB1,LPIN1,ACSL6,GPR12,RIPK3,STON1,KMT5C,RNF212,RNF17,HEXB,TPO,MZF1,TADA2B,ZNF470,CCDC169,ZBED3-AS1,CHPT1,ANKDD1B,EP400P1,TTC41P,NUAK2" MicroRNA hsa-miR-3158:mirSVR_lowEffct hsa-miR-3158:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.71E-26 2.50E-22 5.41E-25 4.95E-24 74 1480 "RALGAPA1,SNX24,MSH2,NCOA1,KCTD12,FGFRL1,BCL2L2,ARHGEF7,AP1G2,TAF1B,RILPL1,SNTG2,DHRS1,POLN,LYSMD3,NGDN,SNCAIP,LRRTM2,FCRL5,FCRL2,ZFYVE16,DMXL1,OCIAD1,NR1H4,B3GLCT,RASA1,DTD2,TMEM33,CLIP4,ZNF419,POLR1D,CRYL1,PACRGL,MBNL2,KIRREL1,MPHOSPH9,LGR6,STX2,DRAM1,STK32B,DLEU1,SUCO,FLT1,SLC34A2,SLC12A2,CGREF1,SNRPF,JPH4,RAPGEF6,ATP8A2,CMPK2,DRC1,MCCC2,ADGRA3,RNF212,SLC7A8,LINC01551,TMPO,IGSF8,NPL,GPN1,ZNF550,UGT2B7,PAPPA2,ZNF470,ZNF84,IL6ST,KCNN2,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,LINC00442,LMNB1" MicroRNA hsa-miR-107:mirSVR_highEffct hsa-miR-107:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.24E-26 2.79E-22 6.00E-25 5.49E-24 65 1143 "RALGAPA1,ABL2,MDM4,COG6,HOMEZ,CUL4A,BLZF1,FAM193A,CCNA1,NOVA1,CACNA1E,RGSL1,CHD1,GPR180,CFAP54,CFAP45,CLOCK,IL20,VCAN,ZFYVE16,SREK1,PTPRC,PPP2R3C,TSEN15,CLIP4,SETDB2,RNASEL,LATS2,MBNL2,SNORA53,MARVELD2,TBC1D19,CLIP1,IVNS1ABP,SLC15A4,SLC22A4,GABRB1,KDM5B,RAPGEF6,NPAS3,SRP72,PCDH17,PPARGC1A,INSM2,TMED2,ATP11A,PPIP5K2,ADGRL3,ADGRA3,GPR12,TDG,CRB1,GTF2H3,RIMBP2,HEXB,ADAMTS19,HTR2A,CCDC169,ZMYM2,KIR2DS4,AMTN,LINC01913,RMST,SPRYD7,LOX" MicroRNA hsa-miR-103:mirSVR_highEffct hsa-miR-103:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.24E-26 2.79E-22 6.00E-25 5.49E-24 65 1143 "RALGAPA1,ABL2,MDM4,COG6,HOMEZ,CUL4A,BLZF1,FAM193A,CCNA1,NOVA1,CACNA1E,RGSL1,CHD1,GPR180,CFAP54,CFAP45,CLOCK,IL20,VCAN,ZFYVE16,SREK1,PTPRC,PPP2R3C,TSEN15,CLIP4,SETDB2,RNASEL,LATS2,MBNL2,SNORA53,MARVELD2,TBC1D19,CLIP1,IVNS1ABP,SLC15A4,SLC22A4,GABRB1,KDM5B,RAPGEF6,NPAS3,SRP72,PCDH17,PPARGC1A,INSM2,TMED2,ATP11A,PPIP5K2,ADGRL3,ADGRA3,GPR12,TDG,CRB1,GTF2H3,RIMBP2,HEXB,ADAMTS19,HTR2A,CCDC169,ZMYM2,KIR2DS4,AMTN,LINC01913,RMST,SPRYD7,LOX" MicroRNA hsa-miR-4299:mirSVR_lowEffct hsa-miR-4299:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.46E-26 3.44E-22 7.36E-25 6.74E-24 80 1730 "SLAMF6,MSH2,ZNF784,BLZF1,ARHGAP5,FAM193A,CENPBD1P1,STARD13,ARHGEF7,CCNA1,MPZL1,LDB2,PCCA,FAM177A1,CDK7,PDE6B,PFKFB2,WDFY2,ITGBL1,PIGR,SNX6,C1orf116,FAM163A,TAPT1,TOGARAM2,LYSMD3,VCAN,C12orf65,DNM3,IFT172,SNX17,BIVM,SPATA18,DMXL1,LOC439933,GUSBP3,RNASEL,LGR6,DHRS2,TCTN2,ELOVL7,FCAR,TNFRSF19,POLK,FLT1,FTLP10,VEZT,TMEM175,PAICS,UFM1,SLC8A1,SLC22A5,YPEL5,LIMCH1,MEGF10,PDS5B,NMNAT2,NAAA,ATP8A2,MRPS27,SRP54,NFASC,RBKS,KLHL20,PCDH17,BRD8,ACSL6,GPR12,RIPK3,DOCK9,C1QTNF9B,SLC7A8,ADAMTS19,ZNF876P,TENT2,PLB1,KIF3C,MFSD2B,FAM71C,LMNB1" MicroRNA hsa-miR-302f:mirSVR_lowEffct hsa-miR-302f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.46E-26 3.44E-22 7.36E-25 6.74E-24 78 1648 "MAP1B,KIAA1211,NLN,CUL4A,WDR19,ATP2B4,NOVA1,CACNA1E,CDKL2,MPZL1,FAM177A1,PCSK1,CDK17,CDK18,CFL2,ZNF595,TAPT1,RCHY1,GNPTAB,TTC37,CEP350,COCH,SACS,TSEN15,DNMT3A,FAM129A,SMC6,AASDH,SETDB2,MBNL2,DCUN1D2,DHRS2,ADGRV1,SH3YL1,FCAR,PIBF1,POLK,SUPT20H,SGCG,FBXO11,BRMS1L,SLC8A1,THADA,SLC12A2,TMEM132D,UGGT2,MEGF10,PDS5B,EAPP,ZNF274,CD244,IQGAP2,MRPS27,RBKS,MCCC2,NMU,PPARGC1A,STRN,ZNF544,PPIP5K2,METAP2,ACSL6,DOCK9,SLC7A8,MSH6,BAZ1A,ADAMTS19,UBE2K,TECRL,GUF1,WDR36,SELENOI,ZMYM2,KIF3C,KIT,AMTN,AXDND1,LMNB1" MicroRNA hsa-miR-493:mirSVR_lowEffct hsa-miR-493:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.24E-26 3.85E-22 8.23E-25 7.54E-24 78 1651 "ADORA1,COG6,MCFD2,APC,MSH2,WDR19,NCOA1,ASTN1,ZNF542P,ATP7B,BCL2L2,PNP,CACNA1E,PCDH9,XPR1,PDE4D,LTB4R,THAP6,EPGN,NCOR2,LRRTM2,FCRL5,ZNF586,PIGG,NUDT12,CEP120,WDR1,PARPBP,EGLN3,RGS12,CLIP4,MEMO1,LRPPRC,EFNA5,LGR6,CWC27,MAEA,ETF1,DLEU1,ELOVL7,SH3YL1,POLK,SUCO,FBXO11,SCYL2,SLC8A1,CCDC88A,POTEM,N4BP2,C1orf112,PUS1,GABRA2,NMNAT2,EAPP,SRP72,MIMT1,MAST4,PPIP5K2,ANO4,EML4,RNF212,XPO4,ZBTB49,ADAMTS19,HMGCR,LTB4R2,ZNF550,SLAIN1,IGF1,ZNF470,SPTSSA,FAM49A,CHPT1,RMST,NUAK2,PABPN1,SKA3,ZNF304" MicroRNA hsa-miR-1303:mirSVR_lowEffct hsa-miR-1303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.36E-26 3.92E-22 8.35E-25 7.64E-24 83 1859 "MCC,TMEM132B,EP400,MCFD2,ATP4B,ATP7B,ARHGEF7,NFKBIA,PNP,ZNF664,DCLK1,PIWIL1,PFKFB2,WDFY2,GPR180,ATAD2B,AKAP6,MPC2,COPA,GNPTAB,HEATR5A,ITSN2,ZFYVE16,SPATA18,LOC439933,CEP350,NUDT12,NR1H4,DTD2,EFNA5,UGT2A3,ELF1,TCTN2,GP6,DEPDC4,ARSK,ABCA11P,ADGRV1,SDC1,MROH9,SUPT20H,VEZT,TM9SF1,BRMS1L,SLC30A6,TADA1,ZNF605,SLC22A4,SLC22A5,NR5A2,LIMCH1,ADCY10,KIF21B,NAAA,DRC1,RBKS,LILRB1,IKBIP,GJA3,MTUS2,ADGRL3,ACSL6,COX18,RNF17,GRSF1,CRB1,GTF3C2,BAZ1A,RASSF6,ZNF721,ADAMTS19,HMGCR,TECRL,ZNF876P,TENT2,VRK2,CCDC169,ZMYM2,KCNJ9,DIAPH3,TTC41P,SKA3,ZNF304" MicroRNA hsa-miR-4255:mirSVR_highEffct hsa-miR-4255:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.04E-26 4.27E-22 9.09E-25 8.33E-24 56 842 "SEMA6A,SNX24,MCFD2,APC,ARHGAP5,ARHGEF7,BTF3,CCNA1,FCHO2,FCGR2C,CDK7,PCSK1,CDK17,PDGFRA,PGGT1B,WDFY2,BOD1L1,HECTD1,FCRL5,PIGG,COG3,PTPRC,SACS,NR1I3,RASA1,RGS12,EFNA5,TXNDC15,MBNL2,ELK3,SLC22A17,ELOVL7,SH3YL1,SUCO,FLT1,IVNS1ABP,CCDC88A,SLC12A2,LIMCH1,HSPH1,ZBTB37,GJA3,PSME4,TMED2,KMT5A,LINC01551,GTF3C2,RAB2B,NSD2,C12orf73,SPTSSA,ZBTB41,CHPT1,KCNN2,LMNB1,IFT88" MicroRNA hsa-miR-138-1*:mirSVR_highEffct hsa-miR-138-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.09E-26 4.30E-22 9.09E-25 8.33E-24 54 778 "MDM4,ANKRD34B,SNX24,CCDC181,SLC4A4,NOVA1,CD1E,UHMK1,FCRLB,FAM177A1,PDGFRA,GLT1D1,ZNF595,WDFY2,HECTD1,HOMER1,TOGARAM2,LYSMD3,PREPL,SNCAIP,CSNK1G3,ITSN2,PRKD1,ZNF586,BIVM,COG3,DMXL1,PTPRC,TINF2,DHFR,SMC6,IRF9,SUCO,SUPT20H,UFM1,ARHGEF40,LIMCH1,MEGF10,PDS5B,NAAA,MRPS27,LILRB1,IKBIP,MTUS2,ANO4,HAL,HEXB,GUF1,VRK2,KCNT2,SPTSSA,LHX9,FIP1L1,KIT" MicroRNA hsa-miR-374b:PITA hsa-miR-374b:PITA_TOP PITA 8.09E-26 4.30E-22 9.09E-25 8.33E-24 54 778 "MDM4,NLN,RGS5,MCFD2,APC,ARHGAP5,ASCL1,NCOA1,STARD13,KCTD12,ARHGEF7,NOVA1,CDK17,PDE4D,ATAD2B,HECTD1,HOMER1,AKAP6,ZFYVE16,COG3,DMXL1,CEP350,TMEM161B,RGS4,CLIP4,LATS2,MBNL2,FAM172A,PCGF3,FNIP1,FOXG1,PEAR1,FOXO1,G2E3,PLEKHA6,ALKAL2,SLC8A1,SLC15A4,MYO16,MYT1L,HSPH1,PCDH17,PPARGC1A,PSME4,ANO4,ACSL6,STON1,TFDP1,BAZ1A,RIMBP2,ADAMTS19,KLF12,UBE2K,ZBTB41" MicroRNA hsa-miR-374a:PITA hsa-miR-374a:PITA_TOP PITA 8.09E-26 4.30E-22 9.09E-25 8.33E-24 54 778 "MDM4,NLN,RGS5,MCFD2,APC,ARHGAP5,ASCL1,NCOA1,STARD13,KCTD12,ARHGEF7,NOVA1,CDK17,PDE4D,ATAD2B,HECTD1,HOMER1,AKAP6,ZFYVE16,COG3,DMXL1,CEP350,TMEM161B,RGS4,CLIP4,LATS2,MBNL2,FAM172A,PCGF3,FNIP1,FOXG1,PEAR1,FOXO1,G2E3,PLEKHA6,ALKAL2,SLC8A1,SLC15A4,MYO16,MYT1L,HSPH1,PCDH17,PPARGC1A,PSME4,ANO4,ACSL6,STON1,TFDP1,BAZ1A,RIMBP2,ADAMTS19,KLF12,UBE2K,ZBTB41" MicroRNA hsa-miR-9*:mirSVR_highEffct hsa-miR-9*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.43E-26 4.48E-22 9.46E-25 8.66E-24 78 1655 "NYNRIN,APAF1,ARHGAP5,SLC4A4,ZNF542P,CCNA1,NRL,CAST,LDB2,FCGR2C,ZNF664,PCK2,PCSK1,PDGFRA,CFL2,PFKFB2,VIT,SLC25A3,GPR180,NRXN1,BOD1L1,THAP6,HOMER1,STRN3,TAPT1,POU2F1,CSNK1G3,ITSN2,DNM3,ZFYVE16,SREK1,COG3,DMXL1,COCH,TBC1D4,PTPRC,OCIAD1,G3BP2,GNPDA2,WDR1,PARPBP,RASA1,CLIP4,SPATA9,GP6,CWC27,ETF1,CLIP1,FCGR3A,GORAB,RELL1,PIBF1,POLK,VEZT,TADA1,SLC12A2,SLC15A4,NR5A2,GABRA2,NAAA,HSPH1,NEDD1,GJB2,INSM2,ATP11A,PPIP5K2,C5orf56,EML4,TDG,BAZ1A,RAB2B,TXK,LHX9,CHPT1,KCNN2,RNASE11,LOX,ZNF304" MicroRNA hsa-miR-651:mirSVR_highEffct hsa-miR-651:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.79E-26 4.68E-22 9.84E-25 9.01E-24 63 1082 "RALGAPA1,ANKRD34B,COG6,ULK1,MSH2,ARL1,ASCL1,SLC4A4,STARD13,CD84,CAST,ZMYM5,PDGFRA,CFL2,WDFY2,MRPL57,LYSMD3,CLOCK,CSNK1G3,LRRTM2,PRKD1,BIVM,COG3,DMXL1,FBXL5,NUDT12,TMEM161B,REST,DTD2,LAP3,MEMO1,CWC27,TRAPPC13,FCGR3B,GORAB,PIBF1,SUCO,FOXG1,FLT3,CCDC88A,SLC12A2,UGGT2,GABRA2,PDS5B,CD244,HSPH1,KLHL20,NPFFR2,FCRLA,GTF2H3,RASSF6,UBE2K,GUF1,PAPPA2,YTHDC2,CENPH,ZNF84,ANKS1B,ZBTB41,FAM151B,NPHS2,CHPT1,LINC01913" MicroRNA hsa-miR-100*:mirSVR_lowEffct hsa-miR-100*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.83E-26 5.23E-22 1.10E-24 1.01E-23 82 1825 "MCC,ADORA1,COG6,EP400,PPFIA4,APC,DDX55,ATP1A2,PPP1R12B,PNP,MORN2,PCCA,PDGFRA,PIWIL1,ZNF595,WDFY2,C1orf116,STRN3,TAPT1,CSNK1G3,ITSN2,DNM3,ZFYVE16,COG3,FBXL5,NUDT12,PTPRC,RABGAP1L,ZNF329,FAM228A,TMEM33,MEMO1,LATS2,ELF1,ELK3,MPHOSPH9,FAM172A,DNAJC27,SPON2,GORAB,MROH9,FLT1,RASA3,VEZT,THADA,ZNF605,PKD2L2,LIMCH1,DCAF11,PDS5B,KDM5B,RAPGEF6,ERAP1,ATP8A2,HSPH1,CMPK2,NEDD1,ERBIN,IKBIP,MIMT1,GJA3,ADGRA3,RIPK3,DOCK9,GPR161,AP4S1,RASSF6,ACTR6,TMPO,RIMBP2,ATP6V0A2,TENT2,WDR36,IGF1,KCNT2,JCHAIN,ZMYM2,ZBED3-AS1,KCNN2,TTC41P,LMNB1,LOX" MicroRNA hsa-miR-485-3p:mirSVR_lowEffct hsa-miR-485-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-25 5.61E-22 1.18E-24 1.08E-23 82 1827 "RGS5,APBB2,APC,DDX55,ARL1,AACS,NCOA1,ATP4B,STARD13,ARHGEF7,PAH,ZMYM5,XPR1,CDK18,RGSL1,PDE4D,PIGR,SNX6,HECTD1,THAP6,TAPT1,SNCAIP,LRRTM2,CEP135,ZFYVE16,IFT172,DGKQ,EPS8L1,CEP120,SUPT7L,PPP2R3C,TSEN15,TMEM161B,LAP3,MARVELD2,DEPDC4,STK32B,DNAJC27,CLIP1,USP44,PCBD2,FGF9,SUCO,FOXO1,FLT1,SUPT20H,ZCCHC8,SGCG,RUBCNL,SLC34A2,FBXO11,NUBPL,CCDC88A,ZNF605,PKD2L2,NR5A2,MYO16,MEGF10,TMEM183A,NPAS3,LRCH1,GJA3,PPIP5K2,METAP2,ANO4,GPR12,TCF7,FCRLA,TEP1,GRSF1,MAEL,SLAIN1,ZNF470,SELENOI,CCDC169,ZNF140,ZBTB41,FIP1L1,RNASE11,IFT88,LOX,ZNF304" MicroRNA hsa-miR-4303:mirSVR_lowEffct hsa-miR-4303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-25 6.25E-22 1.31E-24 1.20E-23 81 1788 "MDM4,ADD1,ATP6V1G3,SEMA6A,CUL4A,ASCL1,ZNF542P,FCRL3,ARHGEF7,DAOA,ZMYM5,CDK17,RGSL1,PDE4D,PDGFRA,PDE6B,CFL2,CHIT1,ZNF595,ITGBL1,POLN,HECTD1,FAM53A,POLE,LYSMD3,NGDN,ZNF586,SNX17,SPATA18,PPP2R3C,TSEN15,RNF31,RB1,POLR1D,SETDB2,RNASEL,MARVELD2,TCTN2,STX2,ARSK,CWC27,MAEA,ABCA11P,PCGF3,CLIP1,SLC22A17,TMEM156,TOMM40L,SUPT20H,NBEA,ALKAL2,MBIP,CCDC88A,N4BP2,C1orf112,MYT1L,KIF21B,DRC1,LRCH1,ZNF544,ATP11A,ADGRL3,STON1,EML4,TDG,COX18,ZBTB49,TPO,ARHGAP30,NSD2,YTHDC2,KCNT2,ZMYM2,FAM49A,KCNN2,FIP1L1,KIF3C,LAD1,NUAK2,SPRYD7,LTA4H" MicroRNA hsa-miR-483-3p:mirSVR_lowEffct hsa-miR-483-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-25 6.39E-22 1.33E-24 1.22E-23 75 1543 "LRRC43,MDM4,SNX24,APC,AACS,ATP1A2,ZNF542P,NFKBIA,CACNA1E,CDKL2,SNTG2,ZMYM5,FAM177A1,RCBTB2,CPNE6,CFAP54,GNPTAB,DNM3,KIAA0040,UBXN2A,FCRL5,NOS1AP,PIGG,DHX9,NUDT12,OCIAD1,PARPBP,RAN,ATG10,RNF31,OGFOD2,ZNF419,POLR1D,GUSBP3,RNF4,MBNL2,TBC1D19,FAM81B,ABCA11P,FNIP1,PIBF1,SUCO,STAB2,DDX51,STPG4,CCDC88A,SLC12A2,EFR3B,ADCY10,NFASC,DRC1,MCCC2,GJA3,ZNF544,ADAM17,ARHGEF28,STON1,C1QTNF9B,FCRLA,NT5C1B,GTF3C2,RIMBP2,NPL,ADAMTS19,GUF1,DCP2,IGF1,PLB1,IRF1,LINC00272,FAM151B,ZBED3-AS1,CHPT1,LETM1,AXDND1" MicroRNA hsa-miR-758:mirSVR_lowEffct hsa-miR-758:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-25 6.47E-22 1.35E-24 1.23E-23 73 1464 "ACOX3,KIAA1211,ANKRD34B,CUL4A,APAF1,FCRL3,LINC02347,DAOA,TAF1B,ODC1,PCDH9,PDGFRA,RCBTB2,WDFY2,NUP37,ATAD2B,LTB4R,THAP6,TAPT1,FCRL5,ZFYVE16,BIVM,COG3,DMXL1,NUDT12,CEP120,RABGAP1L,GNPDA2,PARPBP,RAN,RGS12,UGT2A3,MARVELD2,DHRS2,CWC27,CLIP1,TNFRSF19,SUCO,FMO1,SUPT20H,VEZT,SGCG,RUBCNL,ARHGEF40,SLC12A2,P2RX2,MYT1L,NAAA,ATP8A2,NPAS3,IKBIP,ZBTB37,LPIN1,BRD8,UGT2A1,TMED2,ADGRA3,ACSL6,TCF7,RNF17,TFDP1,ADAMTS19,TRPC4,PAPPA2,WDR36,IGF1,JCHAIN,IL6ST,PLB1,DIAPH3,LINC01913,LIG4,LTA4H" MicroRNA hsa-miR-218-1*:mirSVR_lowEffct hsa-miR-218-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.28E-25 6.79E-22 1.41E-24 1.29E-23 72 1426 "BIRC6,ANKRD34B,NYNRIN,RGS5,FBRSL1,MSH2,BCL2L2,ARHGEF7,BTF3,AP1G2,CDKL2,CAST,PCSK1,STRN3,IL20,VCAN,UBXN2A,PRKD1,FCRL5,MATR3,SNX17,COG3,PTGS2,TBC1D4,DHFR,PARPBP,NR1H4,RB1,POLR1D,CRYL1,SETDB2,EFNA5,LGR6,ZNF671,ARSK,SAP18,ABCA11P,PCGF3,UTP15,SPON2,VEZT,PLEKHA6,C1orf112,MRPS14,SNRPF,RAPGEF6,IKBIP,PPARGC1A,MAST4,LINC02393,PPIP5K2,CNTN2,DOCK9,RNF17,TEP1,ACTR6,TECRL,SLAIN1,PAPPA2,WDR36,DCP2,KCNT2,ZNF84,IL6ST,PLB1,ZBTB41,LHX9,LINC01913,LCP1,FAM71C,SKA3,ZNF304" MicroRNA hsa-miR-505:mirSVR_lowEffct hsa-miR-505:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-25 7.01E-22 1.45E-24 1.33E-23 79 1708 "ATP6V1G3,COG6,FBRSL1,APBB2,STARD13,ATP7B,ARHGEF7,SLC5A6,CAST,FCHO2,CD1D,FCRLB,CHIT1,PGGT1B,SLC25A3,NRXN1,C1orf116,STRN3,EPGN,LYSMD3,IFT172,SPATA18,LOC439933,NUDT12,PTPRC,SACS,PARPBP,ATG10,RASA1,ARGLU1,ZNF329,FAM228A,CLIP4,POLR1D,PACRGL,EFNA5,TXNDC15,MBNL2,ZNF671,DNAJC27,PCGF3,GORAB,VEZT,PAICS,UFM1,THADA,CCDC88A,POTEM,C1orf112,CHFR,UGGT2,LIMCH1,RAPGEF6,NAAA,TMEM183A,ATP8A2,NPAS3,CMPK2,NFASC,LRCH1,NMU,LPIN1,STRN,PPIP5K2,GOLGA3,ADGRL3,KHNYN,RNF212,COX18,RNF17,ZBTB49,MSH6,RASSF6,GUF1,ANKS1B,ZBTB41,TDRD3,KCNJ9,ANKDD1B" MicroRNA hsa-miR-584:mirSVR_highEffct hsa-miR-584:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-25 7.11E-22 1.47E-24 1.35E-23 59 951 "MATN3,KIAA1211,NLN,ANKRD34B,CDKL4,ZNF542P,STARD13,KCTD12,PCDH9,PDGFRA,PIWIL1,CFAP54,PITX1,ADGRF3,AKAP6,MPC2,GNPTAB,BRI3BP,VCAN,C12orf65,LRRTM2,CEP135,BIVM,DMXL1,B3GLCT,RB1,NTN4,TBC1D19,ETF1,SPON2,MROH9,SUPT20H,G2E3,NUBPL,THADA,CCDC88A,SLC12A2,PKD2L2,PDS5B,NAAA,NPAS3,SRP72,IKBIP,TMED2,C5orf56,YIPF7,NCSTN,GTF3C2,TNR,HEXB,GUF1,SLAIN1,ZNF470,PLB1,ANKS1B,CHPT1,KIF2A,LCP1,ZNF304" MicroRNA hsa-miR-549:mirSVR_highEffct hsa-miR-549:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-25 8.54E-22 1.77E-24 1.62E-23 56 854 "NDRG2,TMEM132B,ACOX3,APAF1,BLZF1,ARHGAP5,ARL1,ATP1A2,CCNB1,UHMK1,PCDH9,SCFD2,PFKFB2,AKAP6,CLOCK,CEP135,SREK1,COG3,NUDT12,GNPDA2,TSEN15,GALNT14,RAN,RASA1,RB1,SETDB2,MBNL2,CWC27,IRF9,FCAR,FNIP1,FOXG1,FLT1,VEZT,FBXO11,PKD2L2,NR5A2,ZNF667,LIMCH1,KIF21B,EAPP,ERAP1,ATP8A2,SRP72,BRD8,ATP11A,PPIP5K2,METAP2,ADGRL3,ADGRA3,ARHGEF28,TDG,FCRLA,TMPO,NPL,HEXB" MicroRNA hsa-miR-936:mirSVR_lowEffct hsa-miR-936:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-25 8.74E-22 1.80E-24 1.65E-23 79 1714 "MAP1B,MATN3,MCC,BIRC6,TMEM132B,RGS5,KCTD12,NEDD8,NFATC4,DAOA,CBLN3,FCGR2C,CD1D,CDK7,CDK17,CENPC,CFAP45,SNCAIP,C12orf65,ITSN2,FCRL5,FCRL2,G3BP2,SUPT7L,PPP2R3C,C14orf119,DNMT3A,B3GLCT,RB1,TMEM161B,SLC9C2,GUSBP3,RNF4,DHRS2,STX2,DRAM1,ABCA11P,GORAB,POLK,MROH9,FLT1,FLT3,FTLP10,PLEKHA6,UFM1,P2RX2,C1orf112,SLC22A5,YPEL5,DCAF11,RAPGEF6,ERAP1,ATP8A2,NPAS3,NMU,CFHR4,GJA3,UTP20,SCFD1,ACSL6,STON1,EML4,AP4S1,RASSF6,RAB2B,TMPO,RIMBP2,MAEL,HSD17B4,IGF1,ZNF84,PLB1,LINC00272,SDR39U1,KIF3C,EP400P1,MFSD2B,LINC01913,LMNB1" MicroRNA hsa-miR-92a:mirSVR_highEffct hsa-miR-92a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.65E-25 8.77E-22 1.80E-24 1.65E-23 58 921 "MAP1B,KIAA1211,PITPNM2,CDKL4,ATP2B4,STARD13,NOVA1,FCHO2,CD1D,ZNF595,GPR180,NUP37,JAKMIP1,HECTD1,STRN3,CRHBP,VCAN,C12orf65,FAM169A,ZNF586,SPATA18,COG3,DMXL1,SACS,G3BP2,C14orf119,FAM129A,LAP3,LATS2,RNF4,ABCA11P,PCGF3,USP44,FNIP1,POLK,SUPT20H,BRMS1L,ALKAL2,ZNF605,SLC12A2,PDS5B,NAAA,IQGAP2,NPAS3,RBKS,LRCH1,ZNF544,METAP2,GOLGA3,ANO4,DOCK9,FZD10,ZNF721,TENT2,KCNT2,LCP1,AXDND1,LMNB1" MicroRNA hsa-miR-889:mirSVR_highEffct hsa-miR-889:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-25 8.98E-22 1.84E-24 1.69E-23 69 1317 "MATN3,ACOX3,COG6,MSH2,WDR19,STXBP6,ATP2B4,CDKL2,FCRLB,ZNF664,PCCA,PCDH9,PCK2,ZMYM5,FAM177A1,PCSK1,PDGFRA,CENPC,BOD1L1,HOMER1,MPC2,FCRL2,ZFYVE16,BIVM,LOC439933,PPP2R3C,RB1,TMEM161B,SMC6,TRAPPC12,ARSK,ADGRV1,UTP15,PIBF1,VEZT,BRMS1L,UFM1,THADA,TADA1,CCDC88A,SLC12A2,N4BP2,SLC22A5,NR5A2,YPEL5,JPH4,TMEM183A,ZNF274,HSPH1,CMPK2,LRCH1,IKBIP,SULT1E1,LPIN1,TDG,SLC7A8,AP4S1,BAZ1A,HEXB,TECRL,VRK2,HTR2A,CCDC169,CCDC190,ZMYM2,TDRD3,CHPT1,KIF3C,TTC41P" MicroRNA hsa-miR-4251:mirSVR_highEffct hsa-miR-4251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-25 9.27E-22 1.90E-24 1.74E-23 70 1356 "SMIM15,LRRC43,NLN,COG6,BLZF1,ARHGAP5,ZNF542P,ARHGEF7,PNP,DAOA,CACNA1E,FCHO2,DCLK1,CHD1,ITGBL1,HECTD1,THAP6,HOMER1,C1orf116,TAPT1,LYSMD3,CSNK1G3,CEP135,BIVM,PTGS2,FBXL5,PARPBP,TMEM161B,POLR1D,LATS2,DCUN1D2,ELF1,FAM81B,ETF1,IRF9,LRRN2,RUBCNL,NBEA,ALKAL2,IVNS1ABP,THADA,ZNF605,N4BP2,WDCP,SLC22A5,ZNF667,CHFR,KDM5B,NMNAT2,HSPH1,NPAS3,MIMT1,NMU,MAST4,PPIP5K2,TCF7,ARHGEF28,EML4,TDG,TEP1,TMPO,NPL,ADAMTS19,TMEM174,NLRP8,HTR2A,NSD2,ZMYM2,CAB39L,LMNB1" MicroRNA hsa-miR-488*:mirSVR_lowEffct hsa-miR-488*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-25 9.83E-22 2.01E-24 1.84E-23 75 1554 "MATN3,CUL4A,APC,CENPBD1P1,MYBPC1,KCTD12,CD84,ARHGEF7,PDE4D,GLT1D1,CHD1,SMIM14,ATAD2B,ADGRF3,HOMER1,AKAP6,SNCAIP,VCAN,CEP135,DNM3,UBXN2A,DCAF8,MATR3,SPATA18,COG3,TBC1D4,PARPBP,C14orf119,DNMT3A,GALNT14,RB1,ARGLU1,TMEM161B,ZNF329,AASDH,DTD2,MPHOSPH9,DLEU1,NDUFAF7,N4BP2L2,SUCO,ZCCHC8,FBXO11,G2E3,NBEA,BRMS1L,GFM2,CCDC88A,ZNF605,PKD2L2,SLC15A4,RAPGEF6,ZNF274,IQGAP2,ATP8A2,HSPH1,NFASC,NEDD1,COMMD6,SULT1E1,TMED2,PPIP5K2,ARHGEF28,DOCK9,NT5C1B,GUF1,VRK2,SELENOI,ZMYM2,FIP1L1,KIF2A,KIT,AMTN,TTC41P,CDK2AP1" MicroRNA hsa-miR-562:mirSVR_lowEffct hsa-miR-562:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-25 1.01E-21 2.06E-24 1.89E-23 76 1595 "IL17D,SLAMF6,HOMEZ,MCFD2,NCOA1,CD84,DAOA,MPZL1,PAH,ZNF664,ZMYM5,PDE4D,PDGFRA,GLT1D1,PIWIL1,CFAP45,HOMER1,SNCAIP,IL20,ITSN2,ZFYVE16,IFT172,FBXL5,NUDT12,PTPRH,GNPDA2,FAM129A,RB1,TMEM161B,ZNF329,AASDH,SLC9C2,RGS12,POLR1D,SETDB2,GUSBP3,DHRS2,FAM172A,CWC27,CLIP1,FCAR,FNIP1,N4BP2L2,PIBF1,HSD17B7,STAB2,TM9SF1,BRMS1L,SLC8A1,ARHGEF40,TADA1,C1orf112,YPEL5,PDS5B,JPH4,ERAP1,NPAS3,ANKLE2,CFHR4,SCFD1,ACSL6,NT5C1B,ACTR6,ATP6V0A2,NPL,ADAMTS19,UBE2K,TXK,KCNT2,ZNF324B,SPTSSA,ZBTB41,TMEM178A,DNAH10,RMST,AXDND1" MicroRNA hsa-miR-124*:mirSVR_lowEffct hsa-miR-124*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-25 1.05E-21 2.14E-24 1.96E-23 79 1719 "SFTA3,MCC,BIRC6,RGS5,CENPBD1P1,BTF3,CCNA1,ADGRD1,DAOA,PCK2,PDE4D,CHIT1,PGGT1B,PKP1,JAKMIP1,THAP6,CSNK1G3,C12orf65,ITSN2,PRKD1,MATR3,PIGG,SREK1,DMXL1,GNPDA2,LINC01257,PPP2R3C,NR1H4,LAP3,RGS12,TMEM33,RNASEL,MBNL2,SPATA9,STX2,CWC27,F7,SH3YL1,N4BP2L2,POLK,TM9SF1,FBXO11,NBEA,DDX51,NUBPL,PAICS,UFM1,THADA,ZNF605,P2RX2,SLC15A4,C1orf112,SLC22A4,MYO16,UHRF1BP1L,ERAP1,KDM3B,RBKS,MCCC2,LILRB1,PPARGC1A,ADAM17,PPIP5K2,METAP2,SPIC,RNF17,RIMBP2,MAEL,NPL,HMGCR,TENT2,WDR36,DCP2,TADA2B,ZNF470,ZNF84,KIT,LINC00442,PABPN1" MicroRNA hsa-miR-1267:mirSVR_lowEffct hsa-miR-1267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-25 1.06E-21 2.16E-24 1.98E-23 77 1637 "TMEM132B,RGS5,MSH2,BLZF1,FAM193A,ZNF542P,KCTD12,NOVA1,PNP,CAST,DCLK1,CDK17,PDE4D,PDGFRA,GLT1D1,CHD1,TM9SF2,THAP6,CEP135,FAM169A,FCRL5,MATR3,SNX17,PIGG,COG3,DMXL1,LOC439933,COCH,OCIAD1,TINF2,G3BP2,C12orf42,PARPBP,RNF219,FAM129A,TMEM161B,TMEM33,MEMO1,PACRGL,EFNA5,TXNDC15,MBNL2,TRIM28,ELF1,TBC1D19,F10,POLK,SDC1,SUPT20H,MBIP,PKD2L2,POTEM,NR5A2,LIMCH1,MYO16,ZNF274,ATP8A2,NFASC,LILRB1,SCFD1,ANO4,TCF7,KMT5A,DOCK9,YIPF7,TEP1,NT5C1B,MAEL,NPL,ZNF10,MZF1,ZBED3-AS1,ANKDD1B,TTC41P,MFSD2B,AXDND1,LMNB1" MicroRNA hsa-miR-29b-2*:mirSVR_highEffct hsa-miR-29b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-25 1.07E-21 2.16E-24 1.98E-23 72 1437 "MCC,KIAA1211,ATP6V1G3,HOMEZ,AACS,ATP2B4,CAST,AMDHD1,RILPL1,PCSK1,ITGBL1,LINC01085,LTB4R,THAP6,GNPTAB,POU2F1,LACC1,CSNK1G3,ITSN2,LRRTM2,FCRL5,FCRL2,DDX59,MATR3,DHX9,PTPRH,ATG10,CLIP4,SETDB2,RNF4,MARVELD2,DHRS2,TBC1D19,TLR6,GORAB,PIBF1,SLC34A2,ALKAL2,C1orf112,NR5A2,ZNF667,LIMCH1,PDS5B,RAPGEF6,HSPH1,OXGR1,NPAS3,ERBIN,PCDH17,MIMT1,COMMD6,GJA3,BRD8,ADGRL3,EML4,FCRLA,CRB1,GPR161,TMPO,FZD10,GPN1,TECRL,GUF1,VRK2,KCNT2,MZF1,JCHAIN,SPRYD7,IFT88,LOX,SKA3,ZNF304" MicroRNA hsa-miR-199b-3p:mirSVR_lowEffct hsa-miR-199b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-25 1.10E-21 2.22E-24 2.03E-23 70 1360 "MAP1B,BIRC6,TBC1D14,MCFD2,APBB2,CAMK4,MPZL1,ZMYM5,RGSL1,STRN3,TAPT1,RCHY1,POU2F1,ITSN2,LRRTM2,DNM3,BIVM,CEP350,KLHL3,NUDT12,C14orf119,AASDH,PACRGL,LATS2,FCAMR,ABCA11P,PCBD2,TNFRSF19,PIBF1,POLK,SDC1,FLT1,FTLP10,FBXO11,CCDC92,UFM1,SLC12A2,PDS5B,NAAA,TMEM183A,IQGAP2,ERAP1,HSPH1,RBKS,MCCC2,LRCH1,PCDH17,MIMT1,GJA3,COX7B2,PPIP5K2,METAP2,ADGRL3,DOCK9,ZBTB49,RIMBP2,ZNF721,ATP6V0A2,ADAMTS19,ARHGAP30,WDR36,ZNF470,ZNF84,PLB1,LMLN,EP400P1,DNAH10,RMST,SPRYD7,AXDND1" MicroRNA hsa-miR-199a-3p:mirSVR_lowEffct hsa-miR-199a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-25 1.10E-21 2.22E-24 2.03E-23 70 1360 "MAP1B,BIRC6,TBC1D14,MCFD2,APBB2,CAMK4,MPZL1,ZMYM5,RGSL1,STRN3,TAPT1,RCHY1,POU2F1,ITSN2,LRRTM2,DNM3,BIVM,CEP350,KLHL3,NUDT12,C14orf119,AASDH,PACRGL,LATS2,FCAMR,ABCA11P,PCBD2,TNFRSF19,PIBF1,POLK,SDC1,FLT1,FTLP10,FBXO11,CCDC92,UFM1,SLC12A2,PDS5B,NAAA,TMEM183A,IQGAP2,ERAP1,HSPH1,RBKS,MCCC2,LRCH1,PCDH17,MIMT1,GJA3,COX7B2,PPIP5K2,METAP2,ADGRL3,DOCK9,ZBTB49,RIMBP2,ZNF721,ATP6V0A2,ADAMTS19,ARHGAP30,WDR36,ZNF470,ZNF84,PLB1,LMLN,EP400P1,DNAH10,RMST,SPRYD7,AXDND1" MicroRNA hsa-miR-367:mirSVR_highEffct hsa-miR-367:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.09E-25 1.11E-21 2.24E-24 2.05E-23 62 1064 "MAP1B,KIAA1211,PITPNM2,CDKL4,ATP2B4,STARD13,CCNA1,NOVA1,FCHO2,LDB2,CD1D,CDK17,ZNF595,GPR180,NUP37,JAKMIP1,HECTD1,THAP6,STRN3,CRHBP,VCAN,C12orf65,ZNF586,SPATA18,COG3,DMXL1,G3BP2,FAM129A,LAP3,LATS2,RNF4,ABCA11P,USP44,FNIP1,FGF9,POLK,FBXO11,BRMS1L,ALKAL2,ZNF605,SLC12A2,PDS5B,NAAA,IQGAP2,ERAP1,NPAS3,RBKS,LRCH1,ZNF544,GOLGA3,ANO4,DOCK9,CRB1,FZD10,ZNF721,TENT2,KCNT2,KIT,RMST,AXDND1,LIG4,LMNB1" MicroRNA hsa-miR-519a:mirSVR_lowEffct hsa-miR-519a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.12E-25 1.13E-21 2.27E-24 2.08E-23 79 1721 "ADD1,WDR35,ARHGAP5,NCOA1,ATP4B,KCTD12,MYH6,ATP7B,BCL2L2,NFATC4,NFKBIA,DAOA,CACNA1E,CDKL2,PDE4D,CHD1,PFKFB2,THAP6,THTPA,HEATR5A,FAM169A,DNM3,EPS8L1,SREK1,COG3,CEP350,OCIAD1,G3BP2,GNPDA2,WDR1,RNF219,RB1,MEMO1,LRPPRC,EFNA5,LATS2,MPHOSPH9,CLIP1,IRF9,FGF9,TNFRSF19,POLK,SDC1,PEAR1,FBXO11,NUBPL,SLC8A1,SLC12A2,SLC22A5,ZNF667,GABRB1,KIF21B,ZNF274,UHRF1BP1L,NFASC,TBC1D1,INSM2,ATP11A,MTUS2,ADGRA3,XPO4,RNF17,CRB1,TMPO,RIMBP2,ATP6V0A2,ZNF550,TENT2,IGF1,KCNT2,ZNF140,ZBTB41,ZBED3-AS1,DIAPH3,KIT,LINC00442,TTC7A,LMNB1,ZNF304" MicroRNA hsa-miR-485-3p:mirSVR_highEffct hsa-miR-485-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.38E-25 1.27E-21 2.55E-24 2.33E-23 69 1325 "MATN3,MDM4,BIRC6,WDR35,ASTN1,SLC4A4,CCNA1,FCHO2,CHAMP1,LDB2,SNTG2,CDK17,CENPC,RCBTB2,PFKFB2,NRXN1,PIK3C2B,BOD1L1,AKAP6,LYSMD3,PREPL,CRHBP,VCAN,G3BP2,RABGAP1L,DNMT3A,RB1,RGS12,CLIP4,RNASEL,EIF2B1,FCAMR,STX2,SAP18,ETF1,PCGF3,GORAB,PIBF1,NBEA,MBIP,SLC8A1,N4BP2,C1orf112,LIMCH1,GABRA2,KIF21B,NAAA,ZNF274,OXGR1,PPARGC1A,UGT2A1,KMT5A,ADAMTS19,TENT2,NLRP8,NSD2,ZNF10,ANKS1B,ZMYM2,IRF1,LHX9,ZBED3-AS1,TMEM178A,KCNN2,TTC41P,LIG4,LMNB1,CDK2AP1,PABPN1" MicroRNA hsa-miR-150*:mirSVR_lowEffct hsa-miR-150*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.56E-25 1.36E-21 2.73E-24 2.50E-23 72 1443 "MAP1B,NLN,ANKRD34B,SNX24,ARHGAP5,ADGRD1,CHAMP1,LDB2,PAH,NUP37,ATAD2B,AKAP6,FAM163A,HEATR5A,PREPL,LRRTM2,ZNF586,ZFYVE16,PIGG,SREK1,COG3,DMXL1,NUDT12,GNPDA2,SLC35F6,LINC01257,NR1H4,B3GLCT,ATG10,RASA1,ZNF329,CLIP4,CRYL1,EFNA5,MBNL2,FCAMR,GP6,FAM172A,F10,SUPT20H,PLEKHA6,UFM1,SLC12A2,POTEM,CENPJ,CMPK2,IKBIP,PPARGC1A,GJA3,STRN,GJB2,ZNF544,GOLGA3,ANO4,TCF7,XPO4,SLC7A8,LINC01551,BAZ1A,ACTR6,ATP6V0A2,HSP90B1,UBE2K,DCP2,IGF1,SELENOI,CHPT1,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,SKA3" MicroRNA hsa-miR-325-3p:TargetScan hsa-miR-325-3p TargetScan 2.64E-25 1.41E-21 2.81E-24 2.57E-23 79 1727 "NDRG2,BIRC6,KIAA1211,NLN,ANKRD34B,NYNRIN,ADCY4,MCFD2,PPFIA4,BLZF1,ARL1,AACS,ATP1A2,NLRP4,KCTD12,NEDD8,AP1G2,NOVA1,CBLN3,AMDHD1,MORN2,CHAMP1,CD1E,PCCA,PCSK1,PDGFRA,CFL2,PKP1,CEP135,MPHOSPH8,PRKD1,DCAF8,MATR3,PSME1,CEP350,COCH,GNPDA2,MTX3,FAM129A,RNF31,EMC9,DTD2,RNASEL,RNF4,SBNO1,ELK3,MPHOSPH9,BORA,GMPR2,FNIP1,FBXO11,PLEKHA6,GFM2,P2RX2,CGREF1,NR5A2,DCAF11,MYO16,CIDEB,PDS5B,RAPGEF6,GJB6,NFASC,ATP11A,GOLGA3,GPR12,RIPK3,ARHGEF28,FCRLA,GRSF1,RASSF6,RIMBP2,ADAMTS19,HGFAC,DCP2,SDR39U1,KCNJ9,KIF3C,NUAK2" MicroRNA hsa-miR-148b:mirSVR_highEffct hsa-miR-148b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.86E-25 1.52E-21 3.03E-24 2.77E-23 65 1179 "MAP1B,MATN3,TMEM132B,PITPNM2,WDR19,NCOA1,ATP1A2,ATP4B,STARD13,LINC02347,DAOA,CAST,PCCA,PCDH9,CDK17,WDR66,CEBPE,CFL2,CHD1,PFKFB2,GPR180,JAKMIP1,THAP6,HOMER1,COPA,LYSMD3,CLOCK,ITSN2,DMXL1,NUDT12,SACS,PARPBP,PPP2R3C,RNF219,NR1H4,CLIP4,RNASEL,ARSK,F10,PIBF1,SUCO,SDC1,FLT1,FBXO11,GABRA2,KDM5B,TMEM183A,ZNF274,LRCH1,IKBIP,PPARGC1A,INSM2,ATP11A,TGM1,ADAMTS19,RXFP2,TENT2,YTHDC2,FCRL6,CHPT1,KCNN2,KIT,SPRYD7,AXDND1,LIG4" MicroRNA hsa-miR-3138:mirSVR_lowEffct hsa-miR-3138:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.86E-25 1.52E-21 3.03E-24 2.77E-23 83 1898 "MAP1B,MATN3,MCC,TMEM132B,COG6,DHX37,WDR19,NCOA1,ASTN1,CENPBD1P1,ATP2B4,CARMIL3,ZNF664,CENPC,PIWIL1,ZNF595,ITGBL1,TM9SF2,SNX6,TOGARAM2,PM20D1,CLOCK,SNCAIP,C12orf65,ITSN2,FAM169A,KIAA0040,CTSG,NOS1AP,DCAF8,IFT172,SNX17,COG3,OCIAD1,GNPDA2,LINC01257,SMC6,AASDH,TMEM33,ELK3,MPHOSPH9,DRAM1,ARSK,STK32B,ABCA11P,FCAR,GORAB,FLT1,RASA3,VEZT,SLC30A6,TADA1,CCDC88A,NMNAT2,NAAA,ATP8A2,NFASC,DRC1,ZBTB37,ACSL6,C5orf56,RIPK3,ARHGEF28,RNF212,NCSTN,ACTR6,IGSF8,TXK,POC5,CENPH,PLB1,ZBED3-AS1,CHPT1,FIP1L1,KIF3C,KIR2DL1,KIR2DS4,RILPL2,LINC01913,LINC00442,SPRYD7,LMNB1,SPATA13" MicroRNA hsa-miR-642:mirSVR_lowEffct hsa-miR-642:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.94E-25 1.56E-21 3.10E-24 2.84E-23 85 1985 "SMIM15,KIAA1211,NLN,PITPNM2,ADCY4,RGS5,MCFD2,DHX37,BLZF1,ARL1,FAM193A,ASTN1,CCDC181,B4GALT3,KCTD12,CARMIL3,NFATC4,ARHGEF7,SLC5A6,AP1G2,NOVA1,MPZL1,FCGR2C,CD1E,UHMK1,DCLK1,CDK7,RCBTB2,PIGR,NCR1,POLE,GNPTAB,PREPL,LACC1,FCRL5,NOS1AP,FCRL2,DCAF8,EPS8L1,FBXL5,PTPRC,PTPRH,G3BP2,RABGAP1L,MTX3,FAM129A,LRPPRC,GRTP1,KIRREL1,FAM172A,MAEA,ADGRV1,PCGF3,NDUFAF7,LRRN2,STPG4,ZNF605,CHFR,ACIN1,KDM5B,RAPGEF6,ZNF274,NPAS3,MRPS27,NFASC,KLHL20,PCDH17,ZNF544,DOCK9,KHNYN,COX18,AP4S1,GTF2H3,FZD10,ATP6V0A2,UBE2K,TXK,PLB1,SPTSSA,LINC00272,FAM151B,ANKDD1B,FIP1L1,AXDND1,PABPN1" MicroRNA hsa-miR-34b:mirSVR_highEffct hsa-miR-34b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-25 1.66E-21 3.30E-24 3.02E-23 66 1218 "COG6,WDR19,STXBP6,ATP7B,CAMK4,CD1E,NFXL1,ZNF664,CDK17,PDE4D,PDGFRA,CHD1,ITGBL1,VCAN,BIVM,COG3,DHX9,PTPRC,SUPT7L,ATG10,LAP3,CLIP4,EIF2D,LATS2,MBNL2,TRAPPC12,TCTN2,FAM81B,FCAR,FCGR2B,N4BP2L2,SDC1,FOXG1,HSD17B7,VEZT,ZCCHC8,G2E3,UFM1,SLC12A2,NR5A2,PUS1,MYO16,GABRA2,MYT1L,PDS5B,CMPK2,PCDH17,STRN,PSME4,INSM2,ADGRL3,GPR12,FCRLA,LINC01551,FZD10,MAEL,HPCAL1,HSD17B4,YTHDC2,ZNF470,ZNF84,CHPT1,CAB39L,KIF2A,RMST,MICU2" MicroRNA hsa-let-7b:mirSVR_lowEffct hsa-let-7b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.17E-25 1.68E-21 3.34E-24 3.05E-23 84 1944 "BIRC6,NLN,NYNRIN,UVSSA,ZNF784,NCOA1,STARD13,CDKL2,CAST,PCDH9,CDK18,RGSL1,CCDC122,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,CMTM5,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,ELOVL7,TRAPPC13,PCBD2,FCAR,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FLT1,FTLP10,UFM1,SCYL2,THADA,ZNF605,POTEM,ATP8A2,NPAS3,MRPS27,NFASC,RBKS,MCCC2,ANKLE2,LRCH1,PPARGC1A,UGT2A1,UTP20,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1" MicroRNA hsa-miR-223*:mirSVR_highEffct hsa-miR-223*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.21E-25 1.71E-21 3.37E-24 3.09E-23 67 1256 "RALGAPA1,MATN3,SMIM15,TMEM132B,COG6,WDR35,ULK1,ARHGAP5,FAM193A,SLC4A4,STARD13,SLC5A8,PCK2,CDK17,RGSL1,VIT,WDFY2,ATAD2B,TAPT1,LACC1,CSNK1G3,VCAN,DCAF8,MATR3,FBXL5,CEP350,PTPRC,DTD2,SLC9C2,GUSBP3,PACRGL,KLHL12,FAM172A,DRAM1,TMEM129,FNIP1,PIBF1,SUCO,FLT1,VEZT,G2E3,SLC30A6,SLC12A2,PKD2L2,MYO16,MYT1L,PDS5B,ERAP1,KDM3B,NEDD1,KLHL20,MIMT1,PPIP5K2,MTUS2,ANO4,DOCK9,RASSF6,NPL,UBE2K,LTB4R2,VRK2,NSD2,KCNT2,LINC00272,FAM49A,ZBED3-AS1,AXDND1" MicroRNA hsa-miR-1257:mirSVR_highEffct hsa-miR-1257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.35E-25 1.78E-21 3.51E-24 3.21E-23 60 1003 "ASCL1,NCOA1,KCTD12,CD84,CDK17,PDGFRA,CCDC122,WDFY2,NRXN1,THAP6,TAPT1,RCHY1,RNASE9,POU2F1,NGDN,SNCAIP,LRRTM2,PTPRC,F11R,DHFR,PARPBP,ATG10,LRPPRC,RNASE2,LATS2,GRTP1,MARVELD2,FCAMR,ARSK,SLC22A17,PIBF1,HSD17B7,SUPT20H,NBEA,NLRP2,SCYL2,CCDC88A,NR5A2,UGGT2,ERAP1,NPAS3,LRCH1,IKBIP,TBC1D1,TMED2,ADGRL3,YIPF7,RNF17,CRB1,TGFBI,HAL,ATP6V0A2,KLF12,HMGCR,WDR36,KCNT2,ZMYM2,LINC00442,RMST,SKA3" MicroRNA hsa-miR-624*:mirSVR_highEffct hsa-miR-624*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.43E-25 1.82E-21 3.59E-24 3.29E-23 54 802 "RALGAPA1,LRRC43,WDR35,FAM193A,CCDC181,NFKBIA,NFXL1,SLC5A8,PDGFRA,CFL2,GPR180,MPC2,CLOCK,CSNK1G3,C12orf65,EIF2AK2,DCAF8,ZFYVE16,PTGS2,TMEM161B,AASDH,TXNDC15,LATS2,EIF2B1,CWC27,PCBD2,N4BP2L2,FGF9,RELL1,POLK,NBEA,NUBPL,CCDC88A,SLC12A2,UGGT2,TMEM183A,CD244,UHRF1BP1L,GJB2,ADGRL3,KMT5A,TEP1,MAEL,HEXB,STARD4,NSD2,YTHDC2,ZMYM2,FAM151B,CHPT1,LCP1,TTC7A,AXDND1,LMNB1" MicroRNA hsa-miR-649:mirSVR_highEffct hsa-miR-649:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.65E-25 1.94E-21 3.81E-24 3.49E-23 59 970 "SMIM15,KIAA1211,FAM193A,FCHO2,CD1E,RGSL1,PDE4D,ZNF595,WDFY2,GPR180,ITGBL1,THAP6,HOMER1,TOGARAM2,CSNK1G3,GLT8D2,ZFYVE16,PTPRC,TINF2,C14orf119,TSEN15,RNF219,NR1H4,SLC9C2,TXNDC15,BORA,TRAPPC13,FCGR2B,UTP15,NDUFAF7,GORAB,RELL1,FMO1,STPG4,TADA1,CCDC88A,UGGT2,LIMCH1,CYP1B1-AS1,MYT1L,CENPJ,SRP54,MCCC2,NEDD1,IKBIP,TMED2,ADGRL3,ANO4,KMT5A,ATP6V0A2,HEXB,ADAMTS19,HTR2A,STARD4,KCNT2,ANKS1B,CHPT1,AXDND1,LOX" MicroRNA hsa-miR-148b*:mirSVR_highEffct hsa-miR-148b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.89E-25 2.07E-21 4.06E-24 3.72E-23 64 1149 "MDM4,ANKRD34B,APC,CCNA1,CAST,CD1E,CDK17,PDGFRA,VIT,PGGT1B,ATAD2B,PMCH,RCHY1,SNCAIP,ITSN2,PRKD1,FBXL5,TBC1D4,SACS,RABGAP1L,SLC35F6,RNF219,DNMT3A,CLIP4,ZNF419,SETDB2,SPATA9,ELF1,CWC27,ETF1,FCGR3A,FCGR3B,TNFRSF19,PIBF1,POLK,BRMS1L,ALKAL2,UFM1,IVNS1ABP,LIMCH1,GABRA2,CENPJ,HSPH1,SRP72,NEDD1,IKBIP,PSME4,ZNF544,UTP20,LINC02393,ACSL6,EML4,FCRLA,TEP1,BAZ1A,RASSF6,NPL,ADAMTS19,YTHDC2,IL6ST,LINC00272,TMEM178A,KIT,LINC00442" MicroRNA hsa-miR-653:mirSVR_highEffct hsa-miR-653:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.06E-25 2.16E-21 4.22E-24 3.86E-23 73 1494 "MAP1B,BIRC6,APC,ARHGAP5,STARD13,LINC02347,NOVA1,FCHO2,CHAMP1,LDB2,SCARB1,NFXL1,ZNF664,PCCA,CDK17,RGSL1,TM9SF2,JAKMIP1,HECTD1,POU2F1,LYSMD3,CLOCK,BRI3BP,FAM169A,DNM3,ZNF586,ZFYVE16,PIGG,COG3,DMXL1,LOC439933,NUDT12,PTPRC,OCIAD1,C14orf119,ZNF419,GUSBP3,MBNL2,FAM172A,EFS,ARSK,CWC27,ABCA11P,ADGRV1,CLIP1,F7,GORAB,N4BP2L2,RELL1,PIBF1,SUCO,FLT1,MBIP,CCDC88A,SLC12A2,GABRA2,PDS5B,IKBIP,ZNF544,TBC1D1,SCFD1,ANO4,TEP1,NT5C1B,BAZ1A,RASSF6,ZNF721,HAL,HMGCR,CCDC169,LHX9,ANKDD1B,AXDND1" MicroRNA hsa-miR-142-3p:mirSVR_highEffct hsa-miR-142-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.11E-25 2.19E-21 4.27E-24 3.91E-23 53 773 "ATP6V1G3,EP400,APC,ATP1A2,RAB29,CACNA1E,CDKL2,MORN2,CD1D,FAM177A1,PCSK1,CFL2,GPR180,ITGBL1,HECTD1,AKAP6,STRN3,HEATR5A,ZFYVE16,SPATA18,COG3,CEP350,PARPBP,NR1I3,PACRGL,PCGF3,ELOVL7,FGF9,SUCO,SUPT20H,CCDC88A,FAM114A1,TMEM183A,CMPK2,IKBIP,KLHL20,PSME4,ADGRL3,EML4,BAZ1A,RXFP2,UGT2B7,HSD17B4,STARD4,NSD2,ZFHX2,IL6ST,ZBTB41,ZBED3-AS1,KCNN2,LINC00442,SPRYD7,AXDND1" MicroRNA hsa-miR-302b*:mirSVR_highEffct hsa-miR-302b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.40E-25 2.34E-21 4.56E-24 4.17E-23 71 1417 "SMIM15,MDM4,KIAA1211,NLN,PITPNM2,APBB2,MSH2,CENPBD1P1,ATP1A2,DAOA,CDKL2,CHAMP1,FCGR2C,PCDH9,PDE4D,PDGFRA,CFL2,WDFY2,LINC01085,PREPL,SNCAIP,LACC1,VCAN,LRRTM2,CEP135,DNM3,UBXN2A,FCRL2,MATR3,COG3,DMXL1,LOC439933,RNF219,SLC9C2,CLIP4,CRYL1,NTN4,LATS2,MBNL2,MARVELD2,N4BP2L2,FGFR3,MROH9,SUPT20H,SGCG,FBXO11,NBEA,SLC30A6,N4BP2,YPEL5,GABRA2,MRPS27,CMPK2,LRCH1,KLHL20,TMED2,EML4,TFDP1,LINC01551,ATP6V0A2,UBE2K,ARHGAP30,HMGCR,TECRL,GUF1,TENT2,TADA2B,FAM151B,KIT,TTC41P,RMST" MicroRNA hsa-miR-148a:mirSVR_highEffct hsa-miR-148a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.48E-25 2.38E-21 4.63E-24 4.24E-23 64 1152 "MAP1B,MATN3,TMEM132B,PITPNM2,WDR19,NCOA1,ATP1A2,ATP4B,STARD13,LINC02347,DAOA,CAST,PCCA,PCDH9,CEBPE,CFL2,CHD1,PFKFB2,GPR180,JAKMIP1,HOMER1,LYSMD3,CLOCK,ITSN2,MATR3,DMXL1,NUDT12,SACS,PARPBP,PPP2R3C,RNF219,NR1H4,OGFOD2,CLIP4,RNASEL,ARSK,F10,SUCO,SDC1,FLT1,FBXO11,KDM5B,TMEM183A,ZNF274,LRCH1,IKBIP,PPARGC1A,TBC1D1,INSM2,ATP11A,TGM1,LINC01551,ADAMTS19,RXFP2,TENT2,YTHDC2,FCRL6,CHPT1,KCNN2,ANKDD1B,KIT,SPRYD7,AXDND1,LIG4" MicroRNA hsa-miR-1178:mirSVR_lowEffct hsa-miR-1178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.55E-25 2.42E-21 4.70E-24 4.30E-23 76 1618 "RALGAPA1,SMIM15,KIAA1211,ADCY4,EP400,SNX24,AACS,ARHGEF7,LINC02347,PNP,NRL,FCHO2,SCARB1,UHMK1,FCRLB,PCK2,ZMYM5,CDK17,BOD1L1,THAP6,GNPTAB,CLOCK,PREPL,FAM169A,FCRL5,CEP350,PTPRC,RABGAP1L,LINC01257,PARPBP,NR1I3,RNF31,EIF2D,EFNA5,TBC1D19,STX2,SAP18,DNAJC27,ABCA11P,PCGF3,FCAR,UTP15,TOMM40L,POLK,SUCO,FOXO1,HSD17B7,VEZT,FBXO11,CCDC92,NUBPL,SCYL2,THADA,UGGT2,KDM5B,SRP72,MCCC2,ANKLE2,INSM2,LINC02393,ADGRL3,ADGRA3,ANO4,GRSF1,TGM1,NPL,HPCAL1,IL25,JCHAIN,ZNF470,CCDC169,ANKS1B,LMLN,TTC41P,MFSD2B,LINC00442" MicroRNA hsa-miR-34c-3p:mirSVR_lowEffct hsa-miR-34c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.78E-25 2.54E-21 4.92E-24 4.51E-23 70 1380 "MATN3,NLN,CUL4A,RGS5,MSH2,CCNB1IP1,CD1E,NFXL1,PCDH9,DCLK1,ZMYM5,GLT1D1,CHD1,CCDC122,WDFY2,ITGBL1,SNX6,CLOCK,LACC1,KIAA0040,EIF2AK2,ZNF586,DMXL1,G3BP2,SUPT7L,B3GLCT,RGS4,LAP3,TMEM33,LRPPRC,PACRGL,TXNDC15,LATS2,MARVELD2,DRAM1,FAM81B,PCBD2,SDC1,FOXG1,FOXO1,BRMS1L,UFM1,SLC22A4,PUS1,KIF21B,PDS5B,KDM5B,HSPH1,KDM3B,ANKLE2,LRCH1,COMMD6,STRN,TMED2,ANO4,STON1,YIPF7,LINC01551,UBE2K,HMGCR,GUF1,HTR2A,ZNF84,IL6ST,CCDC190,ZBTB41,KCNN2,FIP1L1,FAM71C,TTC7A" MicroRNA hsa-miR-4317:mirSVR_lowEffct hsa-miR-4317:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-25 2.76E-21 5.33E-24 4.88E-23 65 1192 "BIRC6,HOMEZ,APAF1,MSH2,WDR19,ARL1,STARD13,MPZL1,RILPL1,ZNF664,CDK17,WDR66,RGSL1,WDFY2,BOD1L1,AKAP6,TOGARAM2,EPGN,TTC37,FCRL5,PIGG,OCIAD1,SACS,NR1H4,RASA1,AASDH,SLC9C2,CLIP4,SETDB2,KLHL12,SLC22A17,SH3YL1,PCBD2,FGFR3,SUPT20H,RASA3,FBXO11,POTEM,WDCP,C1orf112,LIMCH1,RAPGEF6,ATP8A2,NFASC,NMU,STON1,EML4,FCRLA,TEP1,GRSF1,TMPO,TPO,ADAMTS19,TRPC4,GUF1,SLAIN1,PAPPA2,PLB1,SDR39U1,TMEM178A,DIAPH3,LINC01913,RMST,LMNB1,ZNF304" MicroRNA hsa-miR-922:mirSVR_highEffct hsa-miR-922:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.30E-25 2.82E-21 5.44E-24 4.98E-23 72 1461 "ARHGAP5,MYBPC1,ARHGEF7,CCNB1,CD1E,PCCA,DCLK1,CDK17,CKMT2,ATAD2B,HOMER1,AKAP6,STRN3,GNPTAB,TOGARAM2,EPGN,LYSMD3,IL20,CSNK1G3,UBXN2A,IFT172,SPATA18,PTGS2,DMXL1,LOC439933,OCIAD1,SACS,G3BP2,RNF219,DNMT3A,RASA1,RGS4,SETDB2,LRPPRC,ADGRV1,N4BP2L2,MROH9,FTLP10,STAB2,SCYL2,TADA1,CCDC88A,SLC12A2,SLC15A4,CGREF1,C1orf112,UGGT2,GABRA2,KIF21B,MCCC2,STRN,DHRS4,INSM2,ATP11A,ADGRL3,STON1,EML4,NCSTN,FCRLA,TMPO,ATP6V0A2,ADAMTS19,HPCAL1,NSD2,SPTSSA,ANKS1B,ZMYM2,CHPT1,CAB39L,SPRYD7,IFT88,LOX" MicroRNA hsa-miR-1286:mirSVR_lowEffct hsa-miR-1286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.33E-25 3.37E-21 6.49E-24 5.94E-23 75 1586 "SMIM15,ADD1,ACOX3,PITPNM2,DDX55,FAM193A,STARD13,BCL2L2,NOVA1,CD1E,SNTG2,RGSL1,WDFY2,CKMT2,CPNE6,HECTD1,AKAP6,POLE,PM20D1,PREPL,NOS1AP,EPS8L1,PTPRC,RABGAP1L,LINC01257,NR1H4,RAN,RASA1,AASDH,RGS12,EIF2D,GRTP1,MBNL2,LGR6,DEPDC4,CWC27,DLEU1,PCGF3,FNIP1,RELL1,PIBF1,SDC1,TM9SF1,NUBPL,SCYL2,CCDC88A,C1orf112,YPEL5,EFR3B,KDM5B,HSPH1,SRP54,GJA3,STRN,TBC1D1,ADGRL3,ANO4,STON1,NCSTN,GRSF1,SLC7A8,BAZ1A,IGSF8,TPO,GUF1,SLAIN1,HTR2A,ZFHX2,IRF1,LHX9,KCNN2,CAB39L,KIF3C,KIR2DL4,KIR2DS4" MicroRNA hsa-miR-29b-1*:mirSVR_highEffct hsa-miR-29b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.70E-25 3.56E-21 6.85E-24 6.27E-23 78 1711 "MCC,ATP6V1G3,COG6,SNX24,ARHGAP5,ATP2B4,BTF3,LINC02347,CAST,FCHO2,PGGT1B,PIK3C2B,UGT2B28,THAP6,AKAP6,STRN3,RCHY1,POU2F1,LYSMD3,SNCAIP,CEP135,UBXN2A,ZFYVE16,SNX17,PTGS2,CEP350,OCIAD1,SLC35F6,PARPBP,FAM129A,ARGLU1,TMEM161B,POLR1D,NTN4,GUSBP3,PACRGL,MARVELD2,TBC1D19,MZB1,CWC27,ETF1,ABCA11P,USP44,GORAB,FNIP1,TNFRSF19,HSD17B7,RUBCNL,NBEA,BRMS1L,UFM1,CYP1B1-AS1,GABRA2,ZNF274,ERAP1,KLHL20,SULT1E1,TCF7,EML4,ZBTB49,RASSF6,ATP6V0A2,NPL,ADAMTS19,HMGCR,TXK,YTHDC2,JCHAIN,ZNF470,PLB1,GALP,ZMYM2,LINC00272,LHX9,ZBED3-AS1,KIF2A,LCP1,NUAK2" MicroRNA hsa-miR-3162:mirSVR_lowEffct hsa-miR-3162:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.98E-25 3.71E-21 7.12E-24 6.52E-23 74 1548 "MCC,BIRC6,KIAA1211,TBC1D14,BLZF1,STXBP6,ATP1A2,SLC4A4,LINC02347,ZMYM5,FAM177A1,ZNF595,WDFY2,PIK3C2B,BOD1L1,GNPTAB,VCAN,CEP135,FAM169A,NOS1AP,ZFYVE16,CEP350,KLHL3,NUDT12,CEP120,OCIAD1,GNPDA2,SLC35F6,WDR1,PARPBP,POLR1D,LRPPRC,PACRGL,EFNA5,KIRREL1,DHRS2,STK32B,TOMM40L,PIBF1,POLK,PEAR1,FLT1,FBXO11,IVNS1ABP,ARHGEF40,CCDC88A,POTEM,MRPS14,EFR3B,MYT1L,KIF21B,NMNAT2,NPAS3,NFASC,LILRB1,GJB2,ZNF544,TCF7,RIPK3,ARHGEF28,STON1,TEP1,MSH6,RIMBP2,NPL,NLRP8,PAPPA2,NPHS2,KIR2DL4,EP400P1,LCP1,LETM1,FAM71C,LOX" MicroRNA hsa-miR-198:mirSVR_lowEffct hsa-miR-198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.24E-25 3.85E-21 7.38E-24 6.75E-23 79 1755 "BIRC6,ACOX3,COG6,TBC1D14,MCFD2,APAF1,APBB2,ARL1,NOP14,NCOA1,ASTN1,FGFRL1,NOVA1,CACNA1E,CAD,TAF1B,MPZL1,XPR1,CDK17,PDE6B,CFL2,CCDC122,ZNF595,CPNE6,ATAD2B,LTB4R,C1orf116,FAM163A,POU2F1,NCOR2,C12orf65,CMTM5,ZFYVE16,EPS8L1,PTGS2,CEP350,NUDT12,PTPRC,SACS,DNMT3A,B3GLCT,ARGLU1,AASDH,CLIP4,CRYL1,SETDB2,KIRREL1,MARVELD2,DHRS2,MZB1,MAEA,TOMM40L,PEAR1,SELP,MROH9,SLC8A1,C1orf112,PDS5B,EAPP,TMEM183A,IQGAP2,OXGR1,RIPK3,DOCK9,TEP1,TMPO,TXK,HTR2A,WDR36,NSD2,ZNF470,GALP,ZBED3-AS1,LMLN,FIP1L1,KIF2A,KIR2DS4,ZDHHC20,CDK2AP1" MicroRNA hsa-miR-1979:mirSVR_lowEffct hsa-miR-1979:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.08E-25 4.30E-21 8.21E-24 7.52E-23 84 1972 "MAP1B,NDRG2,TMEM132B,ACOX3,KIAA1211,SEMA6A,BLZF1,ATP1A2,SLC4A4,ZNF542P,BCL2L2,DAOA,CACNA1E,CDK7,PDGFRA,WDFY2,ITGBL1,PIGR,POLN,HECTD1,PTPRVP,STRN3,BRI3BP,PRKD1,DCAF8,BIVM,PIGG,SREK1,OCIAD1,F11R,G3BP2,SUPT7L,SLC35F6,DNMT3A,METTL11B,POLR1D,RNF4,MBNL2,ELK3,KLHL12,DHRS2,FAM172A,ELOVL7,FCGR3A,TOMM40L,FCGR3B,SPON2,FGF9,PIBF1,FLT3,FMO1,SLC34A2,ARHGEF40,EFR3B,KIF21B,ATP8A2,GJB6,OXGR1,NEDD1,GJA3,MTUS2,GOLGA3,KMT5A,RNF17,TFDP1,GTF3C2,RASSF6,ACTR6,TNR,HSP90B1,GPN1,GUF1,TMEM174,NSD2,ZNF10,IL6ST,GALP,PGAM5,CHPT1,LMLN,FIP1L1,CAB39L,TTC7A,AXDND1" MicroRNA hsa-miR-433:mirSVR_highEffct hsa-miR-433:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.11E-25 4.32E-21 8.23E-24 7.54E-23 61 1056 "WDR35,CUL4A,DDX55,FAM193A,CENPBD1P1,ZNF542P,NLRP4,B4GALT3,CD84,BTF3,RAB29,UHMK1,SLC5A8,CDK17,NRXN1,BOD1L1,ADGRF3,GNPTAB,TOGARAM2,LYSMD3,CSNK1G3,LRRTM2,CEP135,SREK1,PTPRC,SACS,SUPT7L,SLC35F6,B3GLCT,DTD2,KLHL12,TBC1D19,DRAM1,ABCA11P,CLIP1,NDUFAF7,TM9SF1,BRMS1L,THADA,CENPJ,SRP54,SRP72,IKBIP,MIMT1,PPARGC1A,ADGRL3,GPR12,EML4,FCRLA,TMPO,TPO,HSP90B1,PAPPA2,ZNF26,CHPT1,CAB39L,KIF2A,RMST,AXDND1,PABPN1,ZNF304" MicroRNA hsa-miR-508-3p:mirSVR_lowEffct hsa-miR-508-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.55E-25 4.55E-21 8.66E-24 7.93E-23 73 1513 "RALGAPA1,ADD1,KIAA1211,NLN,ATP6V1G3,SEMA6A,APAF1,BLZF1,NCOA1,ATP1A2,BTF3,CAST,MORN2,NFXL1,PCDH9,FAM177A1,XPR1,CHD1,CCDC122,CKMT2,ITGBL1,SYCP3,PREPL,CRHBP,CEP135,UBXN2A,MATR3,SPATA18,DMXL1,FBXL5,DHX9,PTPRC,F11R,GNPDA2,RB1,TMEM161B,SMC6,SLC9C2,POLR1D,RNASEL,MBNL2,UGT2A3,ABCA11P,ELOVL7,PIBF1,SUCO,SELP,FLT1,SUPT20H,TM9SF1,IVNS1ABP,CCDC88A,POTEM,GABRA2,NFASC,PPARGC1A,GJA3,ADGRA3,C1QTNF9B,COX18,NT5C1B,ADAMTS19,UBE2K,TRPC4,TXK,GUF1,NSD2,IGF1,ZNF470,IL6ST,CCDC190,ANKS1B,DNAH10" MicroRNA hsa-miR-10b*:mirSVR_highEffct hsa-miR-10b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.56E-25 4.55E-21 8.66E-24 7.93E-23 62 1093 "NOP14,KCTD12,LINC02347,DAOA,UHMK1,PAH,FAM177A1,CFL2,PFKFB2,SLC25A3,NRXN1,LTB4R,AKAP6,FAM53A,GNPTAB,CRHBP,SNCAIP,FCRL5,SREK1,COCH,CEP120,OCIAD1,G3BP2,SUPT7L,RB1,NTN4,MBNL2,FAM172A,CWC27,ABCA11P,TRAPPC13,GORAB,N4BP2L2,PIBF1,SUCO,FBXO11,NUBPL,IVNS1ABP,SLC12A2,GABRA2,NMNAT2,HSPH1,KLHL20,SULT1E1,METAP2,ADGRA3,ANO4,GPR12,RNF17,ACTR6,ZNF721,GPN1,RXFP2,DCP2,ZNF10,IL6ST,ZNF140,CAB39L,KIR2DS4,KIR3DL2,TTC41P,NUAK2" MicroRNA hsa-miR-3156:mirSVR_highEffct hsa-miR-3156:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-25 4.83E-21 9.16E-24 8.39E-23 68 1318 "MATN3,KIAA1211,SLAMF6,COG6,SNX24,MSH2,ARHGEF7,BTF3,CAST,AMDHD1,FCHO2,CHAMP1,PDGFRA,PIWIL1,CHD1,NRXN1,LTB4R,HECTD1,THAP6,TAPT1,FAM169A,FCRL5,MATR3,DCT,SACS,RABGAP1L,PPP2R3C,C14orf119,NR1H4,B3GLCT,DTD2,ZNF419,POLR1D,ARSK,STK32B,ABCA11P,SH3YL1,FCGR3A,POLK,MROH9,VEZT,RUBCNL,LIMCH1,GABRB1,PDS5B,JPH4,NAAA,TMEM183A,NPAS3,MRPS27,SRP72,MCCC2,ERBIN,PPARGC1A,BRD8,TBC1D1,ACSL6,ZBTB49,GTF3C2,BAZ1A,RASSF6,TMPO,CCDC169,SPTSSA,ZMYM2,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-519c-3p:mirSVR_highEffct hsa-miR-519c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.13E-25 4.85E-21 9.19E-24 8.41E-23 74 1555 "MAP1B,MATN3,MCC,MDM4,BIRC6,EP400,ARL1,ATP12A,SLC4A4,ZNF542P,LINC02347,ADGRD1,NRL,RILPL1,FCHO2,SNTG2,PDGFRA,CFL2,JAKMIP1,TAPT1,RCHY1,FAM53A,GNPTAB,PREPL,NGDN,ITSN2,UBXN2A,DCAF8,ZFYVE16,SNX17,PIGG,FBXL5,CEP120,SACS,EGLN3,FAM129A,LAP3,CLIP4,NTN4,ELK3,ZNF671,DLEU1,N4BP2L2,PIBF1,FOXG1,NBEA,BRMS1L,UFM1,CCDC88A,SNRPF,MYT1L,PDS5B,KDM5B,ERAP1,CMPK2,LRCH1,ERBIN,IKBIP,KLHL20,COMMD6,NPFFR2,TBC1D1,C5orf56,UBC,SLAIN1,NSD2,ANKS1B,IRF1,LHX9,FAM151B,KCNN2,CAB39L,RMST,LIG4" MicroRNA hsa-miR-98:mirSVR_lowEffct hsa-miR-98:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.14E-25 4.86E-21 9.19E-24 8.41E-23 77 1678 "BIRC6,NYNRIN,ZNF784,NCOA1,STARD13,CDKL2,CAST,PCDH9,CDK18,RGSL1,PIK3C2B,ATAD2B,PKP1,HOMER1,C1orf116,AKAP6,IL20,CMTM5,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,GNPDA2,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,ETF1,GMPR2,TRAPPC13,PCBD2,UTP15,TOMM40L,N4BP2L2,SELP,FLT1,FTLP10,SH3BP2,UFM1,SCYL2,THADA,ZNF605,POTEM,ATP8A2,NPAS3,MRPS27,RBKS,MCCC2,ANKLE2,LRCH1,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,GUF1,TENT2,STARD4,MZF1,PLB1,SPTSSA,ANKS1B,ZMYM2,LMLN,DIAPH3,EP400P1,RNASE11,LMNB1" MicroRNA hsa-miR-582-3p:mirSVR_lowEffct hsa-miR-582-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.25E-25 4.92E-21 9.28E-24 8.50E-23 72 1475 "SMIM15,BIRC6,KIAA1211,BLZF1,SLC4A4,ATP2B4,KCTD12,SLC5A6,LINC02347,NOVA1,SYT2,CD1D,ZNF664,PCDH9,XPR1,PDE4D,PDGFRA,CFL2,CFAP54,NRXN1,LINC01085,THAP6,RCHY1,DNM3,EIF2AK2,MATR3,COG3,FBXL5,G3BP2,MTX3,PPP2R3C,NR1H4,FAM129A,FAM228A,TMEM33,MEMO1,RNF4,TRAPPC12,KLHL12,SAP18,ETF1,DLEU1,ELOVL7,PCBD2,UTP15,POLK,FLT1,STAB2,VEZT,CCDC88A,TMEM132D,UGGT2,ERAP1,LRCH1,SULT1E1,LPIN1,BRD8,ZNF544,ATP11A,GPR12,DOCK9,RNF212,LINC01551,ACTR6,HAL,HEXB,GUF1,VRK2,YTHDC2,ZNF84,CHPT1,LOX" MicroRNA hsa-miR-3157:mirSVR_lowEffct hsa-miR-3157:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-24 5.53E-21 1.04E-23 9.54E-23 82 1893 "MCC,IL17D,MDM4,NYNRIN,ARHGAP5,NOP14,ATP1A2,MYH6,NFKBIA,LINC02347,CBLN3,CAST,SCARB1,FCRLB,TSSK4,PCDH9,DCLK1,PCSK1,RGSL1,GLT1D1,RCBTB2,SNX6,C1orf116,CMTM5,SNX17,SREK1,TBC1D4,TINF2,SACS,NR1I3,FAM129A,RNF31,RGS4,RGS12,RNASE2,EFNA5,MBNL2,TRIM28,ELF1,TRAPPC13,FCAR,FCGR3A,TOMM40L,FCGR3B,PEAR1,MROH9,FLT3,STAB2,ZNF446,WDCP,SLC22A4,ZNF667,MEGF10,JPH4,ZNF274,ATP8A2,NPAS3,NFASC,PCDH17,SULT1E1,PPARGC1A,ZNF544,INSM2,ADGRA3,ANO4,RIPK3,STON1,C1QTNF9B,CRB1,SLC7A8,AP4S1,RAB2B,TMEM174,KCNT2,CCDC169,FAM151B,ZBED3-AS1,KCNJ9,FIP1L1,RNASE11,NUAK2,AXDND1" MicroRNA hsa-let-7c:mirSVR_lowEffct hsa-let-7c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-24 5.83E-21 1.10E-23 1.00E-22 80 1809 "BIRC6,NLN,NYNRIN,ZNF784,NCOA1,STARD13,CDKL2,CAST,PCDH9,CDK18,RGSL1,CCDC122,SNX6,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,ETF1,GMPR2,ELOVL7,TRAPPC13,PCBD2,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,UFM1,SCYL2,THADA,ZNF605,POTEM,ATP8A2,NPAS3,MRPS27,NFASC,RBKS,MCCC2,ANKLE2,LRCH1,PPARGC1A,UGT2A1,UTP20,RIPK3,STON1,KHNYN,AP4S1,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1" MicroRNA hsa-miR-302c:mirSVR_highEffct hsa-miR-302c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.17E-24 6.23E-21 1.17E-23 1.07E-22 72 1481 "MDM4,KIAA1211,B4GALT3,ATP7B,ARHGEF7,CCNA1,FCRLB,RFLNA,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,PGGT1B,SNX6,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,SNCAIP,C12orf65,ITSN2,CEP135,SPATA18,DMXL1,TBC1D4,RABGAP1L,GNPDA2,PARPBP,NR1H4,IPO4,CLIP4,NTN4,RNASEL,LATS2,SNORA53,MPHOSPH9,STX2,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,NUBPL,ARHGEF40,YPEL5,MYT1L,CENPJ,ZBTB37,PPARGC1A,PPIP5K2,ADGRL3,GPR12,KMT5C,TDG,NT5C1B,CRB1,MAEL,ARHGAP30,KCNT2,C12orf73,KCNN2,FIP1L1,IFT88,LTA4H" MicroRNA hsa-let-7e:mirSVR_lowEffct hsa-let-7e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-24 6.59E-21 1.24E-23 1.13E-22 84 1985 "BIRC6,NYNRIN,UVSSA,ZNF784,NCOA1,STARD13,CAST,PCDH9,CDK18,RGSL1,GLT1D1,CCDC122,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,CMTM5,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,DCT,CEP350,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,ELOVL7,TRAPPC13,PCBD2,FCAR,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,UFM1,SLC30A6,SCYL2,THADA,ZNF605,POTEM,ATP8A2,NPAS3,MRPS27,NFASC,RBKS,MCCC2,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,RAB2B,MAEL,NPL,ADAMTS19,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1,RNASE11,LINC00442,LMNB1" MicroRNA hsa-miR-3139:mirSVR_lowEffct hsa-miR-3139:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-24 7.05E-21 1.32E-23 1.21E-22 78 1730 "MAP1B,NDRG2,BIRC6,ADD1,EP400,FAM193A,NCOA1,CENPBD1P1,B4GALT3,MYH7,FCRL3,MPZL1,CDK17,CDK18,GLT1D1,PFKFB2,WDFY2,EPN1,GNPTAB,TOGARAM2,NGDN,GALNT9,DNM3,CMTM5,NOS1AP,COCH,SLC35F6,NR1I3,NR1H4,EGLN3,FAM228A,RGS4,PACRGL,ELK3,KLHL12,MARVELD2,DHRS2,PCOTH,TLR6,ARL6IP4,LRRN2,SUCO,SDC1,FLT1,FTLP10,TM9SF1,ARHGEF40,ZNF605,P2RX2,MEGF10,GAK,NPAS3,KDM3B,DHRS4,ZNF544,METAP2,ADGRA3,RNF212,TDG,ZBTB49,RAB2B,NPL,TPO,STARD4,ZNF10,ZFHX2,ZNF324B,GALP,SDR39U1,LHX9,KIR2DL4,KIT,TTC41P,LINC01913,NUAK2,AXDND1,LMNB1,SKA3" MicroRNA hsa-let-7d:mirSVR_lowEffct hsa-let-7d:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-24 7.54E-21 1.41E-23 1.29E-22 79 1774 "BIRC6,NLN,NYNRIN,ZNF784,NCOA1,STARD13,CAST,PCDH9,PCSK1,CDK18,RGSL1,CCDC122,PIK3C2B,ATAD2B,PKP1,LTB4R,HOMER1,AKAP6,IL20,EIF2AK2,DCAF8,ZFYVE16,IFT172,PIGG,CEP350,RABGAP1L,GNPDA2,SLC35F6,TMEM161B,ZNF329,OGFOD2,PACRGL,TXNDC15,DCUN1D2,MARVELD2,TCTN2,ETF1,GMPR2,TRAPPC13,PCBD2,UTP15,TOMM40L,N4BP2L2,RELL1,SELP,FTLP10,SH3BP2,UFM1,SCYL2,THADA,ZNF605,POTEM,ATP8A2,NPAS3,MRPS27,NFASC,RBKS,MCCC2,PPARGC1A,UGT2A1,RIPK3,STON1,KHNYN,SLC7A8,AP4S1,MAEL,NPL,ADAMTS19,HMGCR,TENT2,STARD4,MZF1,PLB1,SPTSSA,ZMYM2,FIP1L1,DIAPH3,EP400P1,LMNB1" MicroRNA hsa-miR-659:mirSVR_highEffct hsa-miR-659:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-24 8.01E-21 1.49E-23 1.37E-22 60 1033 "IL17D,ANKRD34B,COG6,HOMEZ,FBRSL1,CDKL4,MSH2,NCOA1,NFATC4,NOVA1,DAOA,CDKL2,PCSK1,CDK17,CHD1,CFAP54,ATAD2B,NCOR2,IL20,FCRL5,DCAF8,LOC439933,PTPRC,RABGAP1L,PPP2R3C,GUSBP3,EFNA5,TBC1D19,MAEA,TMEM156,FCGR3A,GORAB,FNIP1,TNFRSF19,SDC1,SELP,VEZT,NBEA,STPG4,ZNF667,LIMCH1,SNRPF,PDS5B,NFASC,LRCH1,PPARGC1A,ADGRL3,DOCK9,COX18,FCRLA,NT5C1B,LINC01551,ACTR6,KCNT2,C12orf73,GALP,ZMYM2,EP400P1,LINC01913,NUAK2" MicroRNA hsa-miR-3125:mirSVR_highEffct hsa-miR-3125:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-24 8.13E-21 1.51E-23 1.38E-22 78 1734 "SLAMF6,ANKRD34B,CUL4A,APC,BLZF1,WDR19,ASTN1,CADM3,ATP7B,CD84,ADGRD1,CD1E,PCDH9,PCSK1,RCBTB2,ZNF595,GPR180,PIGR,THAP6,AKAP6,PM20D1,SNCAIP,CEP135,DNM3,CMTM5,FCRL2,ZNF586,CEP350,TBC1D4,C14orf119,TSEN15,EGLN3,RB1,TMEM161B,DTD2,RNASEL,ZNF671,DEPDC4,ABCA11P,IRF9,FGF9,SDC1,FMO1,VEZT,BRMS1L,PAICS,SCYL2,ARHGEF40,CYP1B1-AS1,GABRB1,PDS5B,EAPP,NPAS3,KDM3B,CMPK2,SRP72,MIMT1,SULT1E1,ADGRL3,ANO4,RNF212,NCSTN,CRB1,GTF3C2,BAZ1A,ATP6V0A2,GUF1,HTR2A,WDR36,SPTSSA,CCDC190,IRF1,LHX9,KIT,RNASE11,TTC41P,LMNB1,EEF1AKMT1" MicroRNA hsa-miR-3149:mirSVR_highEffct hsa-miR-3149:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-24 8.22E-21 1.52E-23 1.40E-22 63 1142 "COG6,ARHGEF7,PNP,FCGR2C,UHMK1,CDK7,CCDC122,WDFY2,NRXN1,SNX6,THAP6,AKAP6,CEP135,UBXN2A,BIVM,SREK1,PTPRC,GNPDA2,TSEN15,DNMT3A,RB1,SMC6,AASDH,RGS4,DCUN1D2,ELF1,CWC27,SAP18,ETF1,FCGR3A,FCGR3B,NDUFAF7,FNIP1,FGFR3,THADA,TADA1,CCDC88A,ZNF605,SLC22A4,ZNF667,YPEL5,GABRA2,MYT1L,NPAS3,GC,METAP2,ANO4,GPR12,MAEL,ADAMTS19,NSD2,YTHDC2,FCRL6,ZNF140,ANKS1B,KIF2A,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL2,DNAH10,RMST,AXDND1" MicroRNA hsa-miR-936:mirSVR_highEffct hsa-miR-936:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.62E-24 8.60E-21 1.59E-23 1.46E-22 63 1143 "APC,ARL1,FAM193A,ASCL1,PPP1R12B,CAD,RILPL1,SCARB1,SLC5A8,CFL2,PFKFB2,ZNF595,THAP6,AKAP6,MPC2,POLE,LRRTM2,CEP135,BIVM,CEP350,NUDT12,TBC1D4,PTPRC,PTPRH,PARPBP,EGLN3,AASDH,LRPPRC,PACRGL,LATS2,ADGRV1,CLIP1,NDUFAF7,N4BP2L2,FOXO1,HSD17B7,G2E3,BRMS1L,CCDC88A,ZNF605,NR5A2,GABRA2,PDS5B,JPH4,HSPH1,CMPK2,RBKS,ERBIN,PCDH17,LPIN1,PPARGC1A,STRN,UGT2A1,COX7B2,NT5C1B,CRB1,HPCAL1,STARD4,CCDC169,ANKS1B,ZMYM2,RNASE11,AXDND1" MicroRNA hsa-miR-934:mirSVR_lowEffct hsa-miR-934:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.69E-24 9.01E-21 1.67E-23 1.52E-22 59 1000 "ADD1,CUL4A,RGS5,BLZF1,ASTN1,PNP,TAF1B,MPZL1,CHAMP1,CD1E,PCDH9,DCLK1,CENPC,PFKFB2,ITGBL1,SNX6,BOD1L1,THAP6,IL20,LRRTM2,MATR3,SREK1,DMXL1,NUDT12,GNPDA2,MTX3,C14orf119,EGLN3,B3GLCT,RGS12,NTN4,LRPPRC,MBNL2,TRAPPC12,DRAM1,ABCA11P,TOMM40L,SUCO,SDC1,HSD17B7,NUBPL,IVNS1ABP,TADA1,SLC12A2,SLC22A5,NR5A2,EFR3B,UGGT2,KDM3B,ADGRL3,LILRB4,NT5C1B,RAB2B,NSD2,ZNF10,MZF1,KCNJ9,DIAPH3,LOX" MicroRNA hsa-miR-500:mirSVR_highEffct hsa-miR-500:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-24 1.06E-20 1.95E-23 1.78E-22 67 1298 "CUL4A,SNX24,RGS5,SLC4A4,ATP2B4,KCTD12,ARHGEF7,MPZL1,FCHO2,UHMK1,PCCA,DCLK1,CDK17,PDE4D,CHD1,GPR180,CFAP54,THAP6,AKAP6,STRN3,UBXN2A,FCRL5,ZFYVE16,OCIAD1,G3BP2,DHFR,RASA1,SMC6,SLC9C2,LAP3,TBC1D19,CWC27,POLK,FLT1,TM9SF1,ALKAL2,SCYL2,ARHGEF40,LIMCH1,PDS5B,ZNF274,HSPH1,KDM3B,CMPK2,DRC1,LRCH1,ERBIN,KLHL20,MIMT1,MAST4,ANO4,GPR12,COX18,AP4S1,MAEL,HMGCR,GUF1,STARD4,KCNT2,CCDC169,CHPT1,TMEM178A,RMST,SPRYD7,LMNB1,CDK2AP1,SKA3" MicroRNA hsa-miR-4254:mirSVR_lowEffct hsa-miR-4254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.22E-24 1.18E-20 2.17E-23 1.99E-22 83 1959 "ADD1,ADORA1,KIAA1211,HOMEZ,MCFD2,MSH2,WDR19,MYH6,BCL2L2,CD1D,RFLNA,RGSL1,CHD1,LTB4R,FAM163A,CLOCK,CSNK1G3,C12orf65,CMTM5,NOS1AP,FCRL2,CEP350,NUDT12,TSEN15,NR1I3,B3GLCT,ATG10,RNF31,TMEM161B,OGFOD2,SLC9C2,RGS12,CLIP4,MEMO1,TRAPPC12,KLHL12,ABCA11P,PCGF3,F7,SLC22A17,TMEM129,SPON2,TNFRSF19,FOXG1,GOLGA2P5,SLC8A1,TADA1,ZNF605,SLC12A2,TMEM132D,C1orf112,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,TMEM183A,GJB6,NEDD1,IKBIP,ADGRL3,ANO4,KHNYN,C1QTNF9B,NCSTN,NT5C1B,AP4S1,RASSF6,NPL,ADAMTS19,ARHGAP30,HPCAL1,ZNF470,IL6ST,CCDC169,LINC00272,FIP1L1,CAB39L,LINC01913,LCP1,AXDND1,PABPN1,ZNF304" MicroRNA hsa-miR-3164:mirSVR_lowEffct hsa-miR-3164:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.35E-24 1.25E-20 2.29E-23 2.10E-22 75 1621 "ADD1,TBC1D14,MCFD2,STXBP6,AACS,NFATC4,RAB29,CAST,RILPL1,PAH,NFXL1,ZNF664,ZMYM5,PDE4D,GLT1D1,ITGBL1,HEATR5A,EPGN,CSNK1G3,DCAF8,SPATA18,KLHL3,SUPT7L,RAN,RNF31,ARGLU1,TBC1D19,ZNF671,DLEU1,CLIP1,NDUFAF7,FOXG1,FLT1,STAB2,G2E3,ARHGEF40,WDCP,NR5A2,LIMCH1,GABRB1,KIF21B,PDS5B,CENPJ,NAAA,OXGR1,KDM3B,IKBIP,PCDH17,LPIN1,ZNF544,ATP11A,PPIP5K2,LILRB4,STON1,COP1,SLC7A8,ZBTB49,GTF3C2,HAL,ATP6V0A2,ADAMTS19,NLRP8,WDR36,IGF1,KCNT2,JCHAIN,ZNF84,PLB1,ZMYM2,ZBTB41,CHPT1,FIP1L1,DNAH10,LINC01913,LIG4" MicroRNA hsa-miR-1265:mirSVR_lowEffct hsa-miR-1265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.42E-24 1.29E-20 2.37E-23 2.17E-22 77 1705 "MAP1B,MCC,KIAA1211,NYNRIN,MCFD2,NCOA1,AMDHD1,FAM177A1,XPR1,RGSL1,CPNE6,ATAD2B,PTPRVP,C1orf116,STRN3,LYSMD3,CLOCK,NGDN,SNCAIP,BRI3BP,CSNK1G3,ITSN2,IFT172,DMXL1,LOC439933,EGLN3,FAM228A,TMEM33,PACRGL,MBNL2,SNORA53,ELK3,FCAMR,BORA,ARSK,STK32B,DNAJC27,ADGRV1,GORAB,VEZT,ZCCHC8,SGCG,MBIP,SLC8A1,POTEM,N4BP2,NR5A2,GABRB1,KIF21B,IQGAP2,NFASC,RBKS,MCCC2,LRCH1,LPIN1,PPARGC1A,GJA3,MAST4,CNTN2,DOCK9,RNF212,RNF17,CRB1,TNR,TXK,TMEM174,DCP2,ZNF84,SELENOI,ZMYM2,CHPT1,LMLN,FIP1L1,KIR2DL4,RMST,SPRYD7,LOX" MicroRNA hsa-miR-1911*:mirSVR_lowEffct hsa-miR-1911*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.51E-24 1.34E-20 2.45E-23 2.24E-22 73 1541 "RALGAPA1,ABL2,MAP1B,TMEM132B,ADD1,KIAA1211,SEMA6A,APBB2,DDX55,ASCL1,NCOA1,CD84,BTF3,SLC5A6,RAB29,PCSK1,PDE4D,CHIT1,SNX6,STRN3,TAPT1,EPGN,CMTM5,UBXN2A,DCAF8,SNX17,SPATA18,COG3,PTGS2,CEP350,PTPRH,SLC35F6,WDR1,EGLN3,RNF31,SMC6,OGFOD2,TBC1D19,FAM172A,MAEA,PCGF3,FLT1,HSD17B7,FTLP10,SUPT20H,TMEM175,BRMS1L,ZNF605,N4BP2,GABRB1,KDM5B,ALLC,JPH4,KDM3B,SRP54,IKBIP,KLHL20,PPARGC1A,BRD8,ADGRL3,KMT5A,XPO4,RNF17,CENPH,PLB1,IRF1,DIAPH3,LAD1,LETM1,RMST,SPRYD7,EEF1AKMT1,SKA3" MicroRNA hsa-miR-2110:mirSVR_highEffct hsa-miR-2110:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.54E-24 1.35E-20 2.47E-23 2.26E-22 62 1116 "RALGAPA1,SLAMF6,WDR35,UVSSA,CDKL4,ATP2B4,B4GALT3,AMDHD1,CD1E,RGSL1,CKMT2,LTB4R,THAP6,SNCAIP,LRRTM2,CEP135,PSME1,SREK1,CEP350,NUDT12,PTPRC,SACS,G3BP2,DHFR,NR1I3,NR1H4,EGLN3,FAM129A,ARGLU1,TRAPPC12,SAP18,STK32B,ARL6IP4,N4BP2L2,PIBF1,FLT1,HSD17B7,NUBPL,C1orf112,CYP1B1-AS1,MYT1L,CIDEB,KDM5B,CMPK2,MCCC2,KLHL20,NPFFR2,PPARGC1A,UTP20,INSM2,CRB1,LINC01551,GTF2H3,RIMBP2,HEXB,STARD4,KCNT2,ZNF470,IL6ST,ANKS1B,FAM151B,FIP1L1" MicroRNA hsa-miR-1256:mirSVR_lowEffct hsa-miR-1256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.66E-24 1.41E-20 2.58E-23 2.36E-22 72 1502 "RALGAPA1,ADCY4,APC,BLZF1,ATP2B4,CD84,ARHGEF7,FCHO2,PCSK1,CDK17,RGSL1,PDE4D,CHD1,CCDC122,HECTD1,STRN3,HEATR5A,CLOCK,C12orf65,DNM3,PIGG,DMXL1,F11R,FAM129A,SMC6,AASDH,RGS12,CLIP4,NTN4,TBC1D19,ARSK,PCBD2,UTP15,GORAB,SUCO,FLT1,FMO1,STAB2,RUBCNL,FBXO11,THADA,GABRB1,CIDEB,SRP54,RBKS,LILRB1,PPARGC1A,GJB2,PSME4,ZNF544,METAP2,TEP1,NT5C1B,CRB1,ZBTB49,AP4S1,SLAIN1,NSD2,ZNF84,C12orf73,IL6ST,PLB1,CCDC190,NPHS2,CHPT1,TMEM178A,ANKDD1B,TTC41P,SLAMF9,LINC01913,LETM1,AXDND1" MicroRNA hsa-miR-548n:PITA hsa-miR-548n:PITA_TOP PITA 2.93E-24 1.56E-20 2.84E-23 2.60E-22 59 1011 "ABL2,TBC1D14,CUL4A,FAM193A,SLC4A4,ATP2B4,BCL2L2,NFKBIA,NOVA1,CDKL2,CCNB1,XPR1,PDE4D,CFL2,CHD1,NRXN1,HOMER1,GNPTAB,SNCAIP,ZFYVE16,SREK1,DMXL1,NUDT12,SACS,G3BP2,B3GLCT,RASA1,MBNL2,ELF1,DEPDC4,ETF1,CLIP1,USP44,RELL1,FOXG1,ZCCHC8,RUBCNL,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,KDM3B,LPIN1,GJA3,ATP11A,PPIP5K2,METAP2,TCF7,KMT5A,NCSTN,SLC7A8,RIMBP2,KLF12,GPN1,HMGCR,SLAIN1,LHX9,KIF2A" MicroRNA hsa-miR-4284:mirSVR_lowEffct hsa-miR-4284:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.18E-24 1.69E-20 3.08E-23 2.82E-22 80 1840 "ABL2,SLAMF6,DHX37,UVSSA,ZNF784,WDR19,NCOA1,ARHGEF7,SLC5A6,MPZL1,FCHO2,NFXL1,FCRLB,FAM177A1,XPR1,WDR66,PDGFRA,PDE6B,CCDC122,VIT,POLN,THAP6,POLE,HEATR5A,NGDN,CEP135,KIAA0040,FCRL2,EPS8L1,KLHL3,CEP120,OCIAD1,F11R,TMEM161B,OGFOD2,FAM228A,RGS12,GUSBP3,LRPPRC,PACRGL,TXNDC15,MARVELD2,TCTN2,DRAM1,FCAR,UTP15,TOMM40L,PIBF1,POLK,FLT1,FTLP10,GOLGA2P5,FBXO11,PAICS,SLC30A6,CCDC88A,SLC12A2,EFR3B,DCAF11,GABRB1,NAAA,MCCC2,LPIN1,GJA3,BRD8,ACSL6,EML4,CRB1,AP4S1,RAB2B,ADAMTS19,GUF1,HSD17B4,HTR2A,WDR36,ZMYM2,FAM151B,FIP1L1,CAB39L,RMST" MicroRNA hsa-miR-96*:mirSVR_highEffct hsa-miR-96*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.32E-24 1.76E-20 3.20E-23 2.93E-22 64 1196 "ABL2,MDM4,BIRC6,ACOX3,WDR35,BLZF1,CAST,AMDHD1,MORN2,LDB2,FCGR2C,UHMK1,NFXL1,SLC5A8,PCDH9,PDGFRA,PIWIL1,CHD1,SMIM14,UGT2B28,TAPT1,COPA,DNM3,KIAA0040,FCRL2,COG3,OCIAD1,B3GLCT,RASA1,CLIP4,SPATA9,STK32B,ETF1,ABCA11P,PIBF1,FOXO1,FLT1,SUPT20H,SGCG,GFM2,LIMCH1,GABRB1,TMEM183A,IQGAP2,CMPK2,DRC1,NEDD1,SULT1E1,GJB2,ADAM17,METAP2,ACSL6,GPR12,RIPK3,RIMBP2,ZNF721,ADAMTS19,DCP2,CCDC169,KCNN2,ANKDD1B,TTC41P,DNAH10,AXDND1" MicroRNA hsa-miR-512-5p:mirSVR_lowEffct hsa-miR-512-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.44E-24 1.83E-20 3.31E-23 3.03E-22 78 1757 "ABL2,MDM4,COG6,WDR35,SEMA6A,CUL4A,NOP14,STXBP6,KCTD12,ARHGEF7,CCNA1,CAST,FCGR2C,UHMK1,PCDH9,PFKFB2,LINC01085,THAP6,HOMER1,C1orf116,EPGN,PREPL,SNCAIP,CSNK1G3,EIF2AK2,OCIAD1,RABGAP1L,C14orf119,ATG10,RGS4,ZNF419,RNASEL,UGT2A3,SNORA53,ELK3,MARVELD2,TCTN2,BORA,STK32B,TOMM40L,FGF9,SDC1,FBXO11,NBEA,PLEKHA6,STPG4,SLC8A1,ARHGEF40,ZNF605,SLC12A2,FSHR,SNRPF,RAPGEF6,EAPP,CMPK2,IKBIP,PCDH17,PPARGC1A,GJA3,DHRS4,BRD8,ADGRA3,C5orf56,RNF212,NT5C1B,CRB1,ZBTB49,ATP6V0A2,TECRL,HSD17B4,ANKS1B,PGAM5,TDRD3,KIR2DL1,KIR2DL4,KIR3DL1,AXDND1,SKA3" MicroRNA hsa-miR-520f:mirSVR_lowEffct hsa-miR-520f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-24 1.93E-20 3.48E-23 3.19E-22 79 1801 "MDM4,ADD1,ULK1,RGS5,ZNF784,ATP2B4,FCRL3,NFATC4,ARHGEF7,CCNA1,CBLN3,FCHO2,CD1D,SCARB1,UHMK1,PCCA,DCLK1,FAM177A1,XPR1,CDK17,WDFY2,LTB4R,RCHY1,HEATR5A,SNCAIP,BRI3BP,FAM169A,PRKD1,FCRL5,PTGS2,SUPT7L,RASA1,SETDB2,LATS2,MAEA,ETF1,DLEU1,PCGF3,ELOVL7,SUCO,FLT1,STAB2,SUPT20H,VEZT,NBEA,BRMS1L,CCDC88A,ZNF605,SLC12A2,SLC22A4,SLC22A5,GABRA2,ADCY10,TMEM183A,OXGR1,NPAS3,DRC1,MCCC2,PPARGC1A,ADAM17,KMT5C,CRB1,ZBTB49,ACTR6,FZD10,RIMBP2,GUF1,VRK2,ZNF470,PLB1,IRF1,ZBTB41,LHX9,RNASE11,LINC01913,LETM1,RMST,PABPN1,ZNF304" MicroRNA hsa-miR-127-5p:mirSVR_lowEffct hsa-miR-127-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.77E-24 2.01E-20 3.62E-23 3.31E-22 80 1845 "RALGAPA1,KIAA1211,NYNRIN,WDR35,APC,FAM193A,SLC4A4,STARD13,CADM3,BCL2L2,ARHGEF7,MPZL1,CAST,CHAMP1,CD1D,CD1E,SNTG2,RGSL1,PDE4D,PFKFB2,CCDC122,WDFY2,SMIM14,C1orf116,TAPT1,RNASE9,LACC1,C12orf65,FCRL5,EIF2AK2,FCRL2,ZNF586,MATR3,KLHL3,OCIAD1,G3BP2,RABGAP1L,DNMT3A,ATG10,NTN4,RNF4,MBNL2,MPHOSPH9,LGR6,DHRS2,STX2,PCOTH,FAM81B,DNAJC27,GMPR2,PCGF3,CLIP1,F10,SH3YL1,FCGR3B,HSD17B7,STAB2,SLC8A1,TMEM132D,C1orf112,NR5A2,GABRB1,HSPH1,NFASC,SRP72,PCDH17,CFHR4,PPARGC1A,ANO4,TDG,TGFBI,GPR161,ZBTB49,ADAMTS19,NSD2,CHPT1,KIT,LCP1,LETM1,CDK2AP1" MicroRNA hsa-miR-484:mirSVR_lowEffct hsa-miR-484:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-24 2.07E-20 3.74E-23 3.42E-22 80 1846 "MAP1B,MDM4,ADD1,KIAA1211,NLN,MCFD2,AACS,ATP1A2,SLC4A4,MYH7,NFATC4,ARHGEF7,NOVA1,CBLN3,CD1E,SNTG2,PCDH9,RGSL1,PDGFRA,PDE6B,CFL2,RCBTB2,ADGRF3,NCR1,THAP6,NGDN,CMTM5,NOS1AP,DCAF8,ZFYVE16,MATR3,EPS8L1,TBC1D4,PTPRH,WDR1,NR1H4,B3GLCT,RNF31,RB1,SMC6,OGFOD2,FAM228A,IPO4,KIRREL1,MARVELD2,DHRS2,NDUFAF7,FNIP1,TM9SF1,FBXO11,NUBPL,ARHGEF40,DCAF11,HSPH1,IKBIP,MIMT1,GJA3,MAST4,ZNF544,INSM2,ANO4,TCF7,XPO4,NCSTN,GPR161,ACTR6,TNR,TRPC4,VRK2,CENPH,ZNF470,CCDC190,SDR39U1,FAM49A,KIR2DL4,KIR2DS4,EP400P1,C2orf70,LETM1,NUAK2" MicroRNA hsa-miR-4277:mirSVR_highEffct hsa-miR-4277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.25E-24 2.26E-20 4.06E-23 3.72E-22 68 1355 "KIAA1211,HOMEZ,BLZF1,ATP2B4,NOVA1,PCCA,CDK17,CENPC,VIT,CPNE6,SMIM14,JAKMIP1,HOMER1,NGDN,FAM169A,PRKD1,DCAF8,OCIAD1,SACS,RABGAP1L,SUPT7L,C14orf119,ATG10,RB1,ZNF329,FAM228A,DTD2,CLIP4,POLR1D,RNASEL,DLEU1,UTP15,RELL1,SUCO,FOXG1,MROH9,FLT3,VEZT,BRMS1L,NUBPL,UFM1,SCYL2,ARHGEF40,CCDC88A,CGREF1,N4BP2,SLC22A4,GABRA2,SRP72,PPARGC1A,ADGRA3,ACSL6,TDG,GTF3C2,BAZ1A,RASSF6,GZMB,GPN1,GUF1,SLAIN1,SELENOI,IL6ST,CCDC169,PLB1,KIF2A,LINC01913,AXDND1,SKA3" MicroRNA hsa-miR-1254:mirSVR_lowEffct hsa-miR-1254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.25E-24 2.26E-20 4.06E-23 3.72E-22 83 1979 "MAP1B,ADD1,KIAA1211,SLAMF6,ADCY4,PPFIA4,FAM193A,ASTN1,CENPBD1P1,ZNF542P,CADM3,BCL2L2,NFATC4,LINC02347,CACNA1E,ZNF664,PDE4D,CENPC,VIT,WDFY2,PKP1,AKAP6,POLE,SNCAIP,CSNK1G3,KIAA0040,CMTM5,NOS1AP,EPS8L1,CEP350,FAM129A,OGFOD2,GUSBP3,PACRGL,RNF4,DCUN1D2,KLHL12,FAM81B,ABCA11P,PCGF3,SLC22A17,TNFRSF19,FOXG1,FLT3,STAB2,RASA3,TM9SF1,SLC34A2,C1orf112,SLC22A5,LIMCH1,MEGF10,PDS5B,KDM5B,GAK,JPH4,ZNF274,GJB6,SULT1E1,GJA3,CNTN2,GPR12,STON1,C1QTNF9B,NCSTN,TEP1,CRB1,AP4S1,RASSF6,HPCAL1,VRK2,NSD2,FCRL6,MZF1,CCDC169,PLB1,ZMYM2,KIR2DL4,KIR2DS4,KIT,LINC01913,LCP1,SKA3" MicroRNA hsa-miR-491-3p:mirSVR_highEffct hsa-miR-491-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.94E-24 2.63E-20 4.71E-23 4.31E-22 64 1205 "ABL2,SMIM15,ACOX3,WDR35,SEMA6A,ARHGAP5,NCOA1,ARHGEF7,NOVA1,PNP,FCHO2,PCDH9,PCK2,PDGFRA,CENPC,STRN3,IL20,DDX59,BIVM,DMXL1,NUDT12,PTPRC,NR1H4,B3GLCT,SMC6,RNASE2,LATS2,UGT2A3,LGR6,TBC1D19,FAM172A,DEPDC4,CLIP1,NDUFAF7,FNIP1,FOXO1,FLT1,G2E3,MYT1L,GABRB1,UHRF1BP1L,NEDD1,ERBIN,MIMT1,LPIN1,PPARGC1A,GJA3,STRN,METAP2,C5orf56,KMT5A,TDG,FCRLA,RNF17,RIMBP2,TECRL,GUF1,JCHAIN,ZNF140,GALP,IRF1,LMLN,RPGRIP1,SKA3" MicroRNA hsa-miR-199b-5p:mirSVR_highEffct hsa-miR-199b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.09E-24 2.71E-20 4.84E-23 4.43E-22 55 883 "RALGAPA1,ZNF542P,PCCA,CDK7,CFL2,PFKFB2,ATAD2B,TAPT1,PREPL,UBXN2A,ZNF586,BIVM,PIGG,CEP120,PTPRC,SACS,WDR1,NR1I3,B3GLCT,ZNF329,ZNF419,TXNDC15,FCAMR,FAM172A,DRAM1,CLIP1,F7,USP44,UTP15,RELL1,SELP,MROH9,FTLP10,NBEA,IVNS1ABP,POTEM,GABRA2,ALLC,OXGR1,KDM3B,PPARGC1A,ZNF544,METAP2,ANO4,ARHGEF28,TEP1,CRB1,TMPO,LTB4R2,RXFP2,FCRL6,FAM151B,CHPT1,KIT,CDK2AP1" MicroRNA hsa-miR-550*:mirSVR_lowEffct hsa-miR-550*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.19E-24 2.76E-20 4.93E-23 4.51E-22 65 1244 "BIRC6,SEMA6A,ARHGEF7,AP1G2,ADGRD1,NOVA1,CACNA1E,MPZL1,CAST,NFXL1,SNTG2,PCDH9,PCSK1,PIWIL1,WDFY2,PIK3C2B,JAKMIP1,STRN3,TAPT1,BRI3BP,ITSN2,PRKD1,FCRL5,SREK1,PTPRC,FAM129A,ATG10,SMC6,LRPPRC,EIF2B1,SNORA53,ELF1,STX2,DLEU1,PIBF1,MROH9,FBXO11,SCYL2,SLC12A2,PKD2L2,POTEM,TMEM132D,N4BP2,GABRB1,KIF21B,PDS5B,MRPS27,CMPK2,RBKS,NEDD1,LPIN1,AURKC,ADGRA3,RASSF6,NPL,ADAMTS19,KLF12,TECRL,TENT2,IL6ST,ZMYM2,LMLN,FIP1L1,LMNB1,ZNF304" MicroRNA hsa-miR-708:mirSVR_lowEffct hsa-miR-708:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.30E-24 2.82E-20 5.02E-23 4.60E-22 76 1685 "MAP1B,NDRG2,BIRC6,EP400,CENPBD1P1,B4GALT3,MYH7,FCRL3,MPZL1,CDK17,CDK18,PFKFB2,ADGRF3,EPN1,C1orf116,GNPTAB,TOGARAM2,NGDN,GALNT9,VCAN,DNM3,CMTM5,FCRL5,NOS1AP,COCH,GNPDA2,NR1I3,NR1H4,FAM228A,RGS4,PACRGL,TXNDC15,ELK3,MARVELD2,DHRS2,PCOTH,TLR6,ARL6IP4,SUCO,SDC1,FLT1,FTLP10,TM9SF1,SLC34A2,UFM1,ARHGEF40,ZNF605,P2RX2,MEGF10,OXGR1,KDM3B,DHRS4,ZNF544,METAP2,ADGRA3,LILRB4,RNF212,TDG,ZBTB49,RAB2B,NPL,STARD4,ZNF10,ZFHX2,ZNF470,GALP,SDR39U1,LHX9,KCNN2,KIR2DL4,LINC01913,LCP1,RMST,NUAK2,AXDND1,LMNB1" MicroRNA hsa-miR-373:mirSVR_highEffct hsa-miR-373:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.81E-24 3.09E-20 5.50E-23 5.04E-22 71 1482 "MDM4,BIRC6,KIAA1211,CUL4A,B4GALT3,ATP7B,ARHGEF7,CCNA1,CACNA1E,CD1E,FCRLB,RFLNA,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,PFKFB2,NRXN1,ATAD2B,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,C12orf65,ITSN2,CEP135,FCRL5,SPATA18,NUDT12,TBC1D4,RABGAP1L,GNPDA2,IPO4,CLIP4,NTN4,RNASEL,LATS2,STX2,DRAM1,DNAJC27,IRF9,RELL1,PIBF1,POLK,SUCO,HSD17B7,STAB2,VEZT,FBXO11,BRMS1L,ARHGEF40,NR5A2,YPEL5,MYT1L,CENPJ,ZBTB37,PPIP5K2,MTUS2,GPR12,KMT5C,CRB1,ARHGAP30,KCNT2,C12orf73,PGAM5,KCNN2,DNAH10,IFT88,LTA4H" MicroRNA hsa-miR-590-5p:mirSVR_highEffct hsa-miR-590-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.82E-24 3.10E-20 5.50E-23 5.04E-22 66 1285 "RALGAPA1,COG6,APAF1,MSH2,DDX55,BLZF1,ARHGAP5,ARL1,ARHGEF7,NRL,FCHO2,CCNB1,SLC5A8,XPR1,PDGFRA,CFL2,ZNF595,GPR180,AKAP6,STRN3,HEATR5A,PREPL,SNCAIP,SREK1,NUDT12,TBC1D4,RAN,RB1,CLIP4,RNASEL,MPHOSPH9,LGR6,TBC1D19,CWC27,ELOVL7,TRAPPC13,N4BP2L2,PIBF1,POLK,FOXO1,HSD17B7,SUPT20H,FBXO11,G2E3,STPG4,THADA,LIMCH1,KDM5B,EAPP,NPAS3,KLHL20,METAP2,RNF212,TGFBI,RASSF6,NPL,TECRL,SLAIN1,HSD17B4,ZNF10,KCNT2,ANKS1B,ZMYM2,ZBED3-AS1,CAB39L,CDK2AP1" MicroRNA hsa-miR-21:mirSVR_highEffct hsa-miR-21:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.85E-24 3.11E-20 5.51E-23 5.05E-22 60 1061 "RALGAPA1,COG6,APAF1,MSH2,DDX55,BLZF1,ARL1,SLC4A4,ARHGEF7,NRL,FCHO2,SLC5A8,PDGFRA,CFL2,ZNF595,GPR180,THAP6,AKAP6,PREPL,SNCAIP,KIAA0040,SREK1,TBC1D4,RASA1,ARGLU1,LGR6,TBC1D19,CWC27,ELOVL7,TRAPPC13,PCBD2,FNIP1,N4BP2L2,POLK,SDC1,FOXO1,HSD17B7,SUPT20H,TM9SF1,FBXO11,G2E3,STPG4,LIMCH1,KDM5B,DRC1,KLHL20,ATP11A,TGFBI,RASSF6,TMPO,NPL,ADAMTS19,HSD17B4,FCRL6,ZNF10,KCNT2,ANKS1B,CAB39L,TTC41P,CDK2AP1" MicroRNA hsa-miR-556-5p:mirSVR_lowEffct hsa-miR-556-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.65E-24 3.54E-20 6.26E-23 5.73E-22 72 1526 "TMEM132B,SLAMF6,RGS5,SLC4A4,ZNF542P,NEDD8,CACNA1E,ZNF595,PIK3C2B,PKP1,HECTD1,PREPL,NGDN,SNCAIP,DNM3,UBXN2A,FCRL5,EIF2AK2,SREK1,DHFR,C14orf119,TSEN15,RNF219,NR1I3,NR1H4,FAM129A,AASDH,FAM228A,DTD2,TMEM33,CLIP4,POLR1D,RNASEL,TBC1D19,SH3YL1,FCGR2B,FNIP1,SUCO,FLT1,HSD17B7,SLC12A2,NR5A2,MYO16,GABRA2,MYT1L,KIF21B,NMNAT2,RAPGEF6,CENPJ,NAAA,ERAP1,NFASC,SRP72,MCCC2,LPIN1,ZNF544,COX18,RNF17,GTF3C2,NPL,ZNF10,KCNT2,ZNF84,ZMYM2,ZBED3-AS1,KIF3C,EP400P1,LINC01913,RMST,LIG4,LMNB1,LTA4H" MicroRNA hsa-miR-370:mirSVR_lowEffct hsa-miR-370:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.90E-24 3.67E-20 6.48E-23 5.93E-22 83 1994 "HOMEZ,EP400,MCFD2,STXBP6,AACS,ATP1A2,CBLN3,CD1D,SCARB1,WDFY2,PKP1,ADGRF3,COPA,RNASE9,POU2F1,EPGN,CLOCK,GALNT9,VCAN,ZFYVE16,SNX17,SPATA18,EPS8L1,FBXL5,COCH,CEP120,RABGAP1L,SLC35F6,PXMP2,NR1H4,DNMT3A,OGFOD2,RGS4,GUSBP3,RNF4,DHRS2,ZNF219,SAP18,STK32B,FCGR3A,TOMM40L,FCGR3B,RELL1,POLK,PEAR1,FOXO1,FLT1,HSD17B7,STAB2,VEZT,NUBPL,ZNF605,TMEM132D,ZNF274,ATP8A2,ZNF544,PPIP5K2,ANO4,ARHGEF28,STON1,EML4,LINC01551,GZMH,RIMBP2,ADAMTS19,GUF1,SLAIN1,IL25,MZF1,SELENOI,IL6ST,PLB1,ZMYM2,ZBED3-AS1,KCNJ9,FIP1L1,CAB39L,KIR2DL4,KIR2DS4,RILPL2,MFSD2B,LIG4,PABPN1" MicroRNA hsa-miR-489:mirSVR_lowEffct hsa-miR-489:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.91E-24 3.68E-20 6.48E-23 5.93E-22 80 1863 "MDM4,BIRC6,ULK1,CDKL4,BLZF1,ASCL1,AACS,CENPBD1P1,ATP1A2,PNP,CAST,MORN2,CD1D,SNTG2,PCDH9,PCSK1,RGSL1,PDGFRA,CHD1,PFKFB2,NRXN1,PIGR,CLOCK,VCAN,FCRL5,MATR3,DMXL1,LOC439933,KLHL3,PTPRC,F11R,G3BP2,PXMP2,PARPBP,RAN,RASA1,RGS4,RGS12,EFNA5,TXNDC15,GRTP1,SPATA9,ELF1,ARSK,PCGF3,FNIP1,FGF9,VEZT,G2E3,BRMS1L,NUBPL,CHFR,UGGT2,CYP1B1-AS1,NMNAT2,NAAA,CD244,NPAS3,NFASC,MCCC2,GJA3,MAST4,PPIP5K2,GOLGA3,ADGRA3,ARHGEF28,RNF212,CRB1,TGFBI,ACTR6,MAEL,HSP90B1,ZNF10,ZMYM2,LHX9,FAM49A,ZBED3-AS1,KIR2DS4,EP400P1,MICU2" MicroRNA hsa-miR-3144-3p:mirSVR_highEffct hsa-miR-3144-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.07E-24 4.29E-20 7.56E-23 6.92E-22 56 926 "SMIM15,MDM4,COG6,WDR35,ARL1,ASTN1,CACNA1E,SLC5A8,CFL2,GPR180,NRXN1,ADGRF3,THAP6,AKAP6,TAPT1,TOGARAM2,LYSMD3,KIAA0040,UBXN2A,COG3,CEP350,CEP120,PTPRC,OCIAD1,SACS,G3BP2,RABGAP1L,TSEN15,RGS12,TXNDC15,UGT2A3,ARSK,CWC27,TRAPPC13,NDUFAF7,N4BP2L2,VEZT,CENPJ,ERAP1,IKBIP,COMMD6,MAST4,TEP1,MSH6,GTF2H3,RASSF6,NPL,GUF1,NLRP8,NSD2,CCDC169,FAM151B,FIP1L1,CAB39L,LINC01913,AXDND1" MicroRNA hsa-miR-4274:mirSVR_lowEffct hsa-miR-4274:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.28E-24 4.40E-20 7.74E-23 7.08E-22 69 1411 "MATN3,NDRG2,APC,ARHGAP5,ARL1,ATP7B,ARHGEF7,CCNA1,NOVA1,CBLN3,ODC1,FCGR2C,PAH,SNTG2,ZMYM5,CDK17,PFKFB2,GPR180,TM9SF2,LINC01085,ATAD2B,THAP6,RCHY1,HEATR5A,KIAA0040,MATR3,SNX17,TINF2,RABGAP1L,DHFR,SUPT7L,TMEM161B,RGS4,CLIP4,PACRGL,ELF1,MARVELD2,SAP18,ADGRV1,FBXO11,BRMS1L,NUBPL,UFM1,THADA,ARHGEF40,TADA1,LIMCH1,GABRA2,CIDEB,PDS5B,NAAA,TMEM183A,ZNF274,IQGAP2,ATP8A2,LRCH1,LPIN1,PPARGC1A,XPO4,RNF17,GPN1,ARHGAP30,SLAIN1,WDR36,ZNF470,TMEM178A,KIF3C,SLAMF9,PABPN1" MicroRNA hsa-miR-532-3p:mirSVR_lowEffct hsa-miR-532-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.59E-24 4.57E-20 8.01E-23 7.34E-22 81 1913 "MDM4,ADORA1,NLN,SLAMF6,COG6,AACS,ATP4B,BTF3,CDKL2,CAST,PCCA,PIGR,POLN,THAP6,STRN3,GNPTAB,SNCAIP,CEP135,PRKD1,DCAF8,EPS8L1,PIGG,FBXL5,OCIAD1,F11R,G3BP2,LINC01257,RB1,GUSBP3,PACRGL,LATS2,GRTP1,RNF4,MBNL2,DHRS2,GP6,DRAM1,DLEU1,F7,TMEM156,NDUFAF7,LRRN2,SUCO,FLT1,HSD17B7,SFSWAP,ZNF446,ARHGEF40,TADA1,ZNF605,CGREF1,SNRPF,NMNAT2,ERAP1,ATP8A2,OXGR1,DRC1,GCKR,MCCC2,NEDD1,IKBIP,DHRS4,LILRB4,ARHGEF28,COX18,TNR,NPL,KLF12,UBE2K,ARHGAP30,TMEM174,PAPPA2,WDR36,NSD2,PLB1,ZBTB41,EP400P1,RNASE11,AXDND1,LOX,ZNF304" MicroRNA hsa-miR-222*:mirSVR_highEffct hsa-miR-222*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.68E-24 4.61E-20 8.08E-23 7.40E-22 55 893 "BIRC6,NCOA1,NOVA1,CAD,CAST,RILPL1,DCLK1,CDK7,PDGFRA,CFL2,PFKFB2,LINC01085,PTPRVP,GNPTAB,PREPL,C12orf65,LRRTM2,BIVM,TBC1D4,PTPRC,PTPRH,G3BP2,PARPBP,EGLN3,RB1,AASDH,DTD2,SLC9C2,ELF1,MARVELD2,STX2,ABCA11P,ADGRV1,TRAPPC13,FCGR3A,FCGR3B,GORAB,TNFRSF19,FOXO1,HSD17B7,CCDC88A,ZNF605,SLC12A2,SLC22A5,ERAP1,HSPH1,RBKS,PCDH17,LPIN1,RNF17,ZNF721,FAM151B,KIF2A,AXDND1,LMNB1" MicroRNA hsa-miR-3140:mirSVR_highEffct hsa-miR-3140:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.18E-24 4.88E-20 8.53E-23 7.81E-22 68 1374 "ARHGEF7,CCNA1,CAST,ODC1,ZNF664,PCDH9,TSTD1,ITGBL1,HECTD1,AKAP6,RNASE9,TOGARAM2,VCAN,CEP135,FCRL5,PIGG,COG3,CEP350,COCH,PTPRC,TSEN15,RNF219,EGLN3,RASA1,RB1,PACRGL,RNASEL,MPHOSPH9,CWC27,ABCA11P,PCGF3,CLIP1,F7,F10,TRAPPC13,PIBF1,FLT1,FLT3,SLC34A2,C1orf112,LIMCH1,MYT1L,TMEM183A,ERAP1,HSPH1,MRPS27,LRCH1,PCDH17,ZBTB37,GJA3,ADAM17,METAP2,ADGRL3,ANO4,FCRLA,RNF17,RASSF6,TMPO,ZNF721,ADAMTS19,ARHGAP30,TXK,ZNF10,ZMYM2,ANKDD1B,FIP1L1,CAB39L,LMNB1" MicroRNA hsa-miR-548p:PITA hsa-miR-548p:PITA_TOP PITA 9.64E-24 5.13E-20 8.95E-23 8.20E-22 55 895 "MAP1B,HOMEZ,APBB2,APC,WDR19,STXBP6,ATP1A2,ATP2B4,KCTD12,BTF3,NFXL1,PDE4D,SMIM14,ATAD2B,HECTD1,STRN3,COPA,IL20,DNM3,DCAF8,ZFYVE16,BIVM,SREK1,COG3,RASA1,RB1,ARGLU1,DTD2,CLIP4,LATS2,MBNL2,FAM172A,ETF1,SDC1,FLT3,ZCCHC8,CHFR,MYT1L,KIF21B,IQGAP2,HSPH1,ANKLE2,ERBIN,LPIN1,TFDP1,RAB2B,FZD10,TRPC4,GPN1,WDR36,NSD2,DCP2,IGF1,KCNT2,SPTSSA" MicroRNA hsa-miR-513c:mirSVR_highEffct hsa-miR-513c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-23 5.57E-20 9.71E-23 8.89E-22 62 1147 "MDM4,KCTD12,NOVA1,CD1D,FCRLB,PGGT1B,WDFY2,SNX6,PKP1,PREPL,CSNK1G3,PRKD1,NOS1AP,ZNF586,NUDT12,WDR1,NR1H4,DNMT3A,ATG10,TMEM161B,REST,LAP3,PACRGL,LGR6,DHRS2,TBC1D19,STX2,ADGRV1,GORAB,FOXG1,NBEA,THADA,CCDC88A,NAAA,CMPK2,LRCH1,KLHL20,PCDH17,MAST4,UTP20,INSM2,ADGRL3,TCF7,DOCK9,TDG,NPL,HEXB,UBE2K,TXK,GUF1,TENT2,TPTE2,YTHDC2,JCHAIN,SPTSSA,ANKS1B,ZMYM2,FAM49A,TTC41P,AXDND1,LMNB1,MICU2" MicroRNA hsa-miR-30a:PITA hsa-miR-30a:PITA_TOP PITA 1.07E-23 5.71E-20 9.86E-23 9.03E-22 54 863 "ABL2,BIRC6,SEMA6A,PITPNM2,CAMK4,PCDH9,XPR1,CDK17,PDE4D,CFL2,CHD1,SMIM14,SNX6,PIK3C2B,ATAD2B,PITX1,BOD1L1,LYSMD3,CLOCK,NCOR2,LRRTM2,MATR3,CEP350,DNMT3A,RASA1,TMEM33,MBNL2,ELF1,STX2,USP44,FOXG1,RUBCNL,NR5A2,GABRB1,PDS5B,JPH4,KLHL20,PCDH17,PPARGC1A,TBC1D1,TMED2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,RIMBP2,TENT2,ZBTB41,FAM49A,LMLN,KIF3C" MicroRNA hsa-miR-30d:PITA hsa-miR-30d:PITA_TOP PITA 1.07E-23 5.71E-20 9.86E-23 9.03E-22 54 863 "ABL2,BIRC6,SEMA6A,PITPNM2,CAMK4,PCDH9,XPR1,CDK17,PDE4D,CFL2,CHD1,SMIM14,SNX6,PIK3C2B,ATAD2B,PITX1,BOD1L1,LYSMD3,CLOCK,NCOR2,LRRTM2,MATR3,CEP350,DNMT3A,RASA1,TMEM33,MBNL2,ELF1,STX2,USP44,FOXG1,RUBCNL,NR5A2,GABRB1,PDS5B,JPH4,KLHL20,PCDH17,PPARGC1A,TBC1D1,TMED2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,RIMBP2,TENT2,ZBTB41,FAM49A,LMLN,KIF3C" MicroRNA hsa-miR-30b:PITA hsa-miR-30b:PITA_TOP PITA 1.07E-23 5.71E-20 9.86E-23 9.03E-22 54 863 "ABL2,BIRC6,SEMA6A,PITPNM2,CAMK4,PCDH9,XPR1,CDK17,PDE4D,CFL2,CHD1,SMIM14,SNX6,PIK3C2B,ATAD2B,PITX1,BOD1L1,LYSMD3,CLOCK,NCOR2,LRRTM2,MATR3,CEP350,DNMT3A,RASA1,TMEM33,MBNL2,ELF1,STX2,USP44,FOXG1,RUBCNL,NR5A2,GABRB1,PDS5B,JPH4,KLHL20,PCDH17,PPARGC1A,TBC1D1,TMED2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,RIMBP2,TENT2,ZBTB41,FAM49A,LMLN,KIF3C" MicroRNA hsa-miR-30e:PITA hsa-miR-30e:PITA_TOP PITA 1.07E-23 5.71E-20 9.86E-23 9.03E-22 54 863 "ABL2,BIRC6,SEMA6A,PITPNM2,CAMK4,PCDH9,XPR1,CDK17,PDE4D,CFL2,CHD1,SMIM14,SNX6,PIK3C2B,ATAD2B,PITX1,BOD1L1,LYSMD3,CLOCK,NCOR2,LRRTM2,MATR3,CEP350,DNMT3A,RASA1,TMEM33,MBNL2,ELF1,STX2,USP44,FOXG1,RUBCNL,NR5A2,GABRB1,PDS5B,JPH4,KLHL20,PCDH17,PPARGC1A,TBC1D1,TMED2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,RIMBP2,TENT2,ZBTB41,FAM49A,LMLN,KIF3C" MicroRNA hsa-miR-30c:PITA hsa-miR-30c:PITA_TOP PITA 1.07E-23 5.71E-20 9.86E-23 9.03E-22 54 863 "ABL2,BIRC6,SEMA6A,PITPNM2,CAMK4,PCDH9,XPR1,CDK17,PDE4D,CFL2,CHD1,SMIM14,SNX6,PIK3C2B,ATAD2B,PITX1,BOD1L1,LYSMD3,CLOCK,NCOR2,LRRTM2,MATR3,CEP350,DNMT3A,RASA1,TMEM33,MBNL2,ELF1,STX2,USP44,FOXG1,RUBCNL,NR5A2,GABRB1,PDS5B,JPH4,KLHL20,PCDH17,PPARGC1A,TBC1D1,TMED2,METAP2,ADGRL3,ADGRA3,ANO4,EML4,TDG,TFDP1,RIMBP2,TENT2,ZBTB41,FAM49A,LMLN,KIF3C" MicroRNA hsa-miR-200c*:mirSVR_lowEffct hsa-miR-200c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-23 6.31E-20 1.09E-22 9.95E-22 66 1302 "BIRC6,SEMA6A,ARHGEF7,AP1G2,ADGRD1,NOVA1,CACNA1E,MPZL1,CAST,NFXL1,SNTG2,PCDH9,PCSK1,PIWIL1,WDFY2,PIK3C2B,JAKMIP1,STRN3,TAPT1,BRI3BP,ITSN2,PRKD1,FCRL5,SREK1,PTPRC,GNPDA2,EGLN3,FAM129A,ATG10,SMC6,LRPPRC,EIF2B1,SNORA53,STX2,PIBF1,MROH9,FBXO11,SCYL2,SLC12A2,PKD2L2,POTEM,TMEM132D,N4BP2,SLC22A4,GABRB1,KIF21B,PDS5B,MRPS27,CMPK2,RBKS,NEDD1,LPIN1,AURKC,ADGRA3,RASSF6,ADAMTS19,KLF12,TECRL,TENT2,IL6ST,ZMYM2,ZBED3-AS1,LMLN,FIP1L1,LMNB1,ZNF304" MicroRNA hsa-miR-320a:mirSVR_highEffct hsa-miR-320a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-23 6.53E-20 1.12E-22 1.03E-21 69 1421 "SFTA3,SMIM15,SEMA6A,WDR19,ARHGEF7,CACNA1E,LDB2,PCCA,PCDH9,ZMYM5,RGSL1,GLT1D1,RCBTB2,VIT,MRPL57,LINC01085,BOD1L1,THAP6,AKAP6,POU2F1,CLOCK,CEP135,SPATA18,SREK1,DMXL1,TBC1D4,CEP120,SUPT7L,WDR1,FAM129A,RASA1,LRPPRC,EIF2D,RNASEL,TXNDC15,GRTP1,EIF2B1,ZNF671,EFS,ADGRV1,PCGF3,USP44,NDUFAF7,PIBF1,SUPT20H,VEZT,ZCCHC8,FBXO11,MBIP,C1orf112,LIMCH1,GABRB1,PDS5B,ZBTB37,BRD8,INSM2,ATP11A,PPIP5K2,METAP2,C5orf56,TDG,BAZ1A,MAEL,RXFP2,POC5,SPTSSA,ANKS1B,NPHS2,MFSD2B" MicroRNA hsa-miR-320b:mirSVR_highEffct hsa-miR-320b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.23E-23 6.53E-20 1.12E-22 1.03E-21 69 1421 "SFTA3,SMIM15,SEMA6A,WDR19,ARHGEF7,CACNA1E,LDB2,PCCA,PCDH9,ZMYM5,RGSL1,GLT1D1,RCBTB2,VIT,MRPL57,LINC01085,BOD1L1,THAP6,AKAP6,POU2F1,CLOCK,CEP135,SPATA18,SREK1,DMXL1,TBC1D4,CEP120,SUPT7L,WDR1,FAM129A,RASA1,LRPPRC,EIF2D,RNASEL,TXNDC15,GRTP1,EIF2B1,ZNF671,EFS,ADGRV1,PCGF3,USP44,NDUFAF7,PIBF1,SUPT20H,VEZT,ZCCHC8,FBXO11,MBIP,C1orf112,LIMCH1,GABRB1,PDS5B,ZBTB37,BRD8,INSM2,ATP11A,PPIP5K2,METAP2,C5orf56,TDG,BAZ1A,MAEL,RXFP2,POC5,SPTSSA,ANKS1B,NPHS2,MFSD2B" MicroRNA hsa-miR-345:mirSVR_lowEffct hsa-miR-345:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.28E-23 6.79E-20 1.17E-22 1.07E-21 74 1626 "LRRC43,BIRC6,ADD1,WDR35,AACS,ATP4B,CD1E,PAH,ZMYM5,PCSK1,PDE4D,ZNF595,EPN1,NGDN,BRI3BP,LACC1,FAM169A,DDX59,EPS8L1,COG3,DMXL1,TBC1D4,PTPRC,TINF2,G3BP2,PARPBP,PPP2R3C,C14orf119,DNMT3A,SLC9C2,GRTP1,RNF4,EIF2B1,ELF1,MPHOSPH9,EFS,STK32B,DLEU1,TRAPPC13,FNIP1,RELL1,PIBF1,SUCO,NUBPL,SLC8A1,ARHGEF40,C1orf112,ZNF667,EFR3B,MEGF10,HSPH1,MRPS27,DRC1,LILRB1,ZBTB37,ZNF544,PPIP5K2,ADGRA3,ACSL6,GPR12,STON1,FCRLA,ZBTB49,GTF3C2,ATP6V0A2,HEXB,NSD2,JCHAIN,SELENOI,IL6ST,PLB1,SPTSSA,LCP1,FAM71C" MicroRNA hsa-miR-1179:mirSVR_highEffct hsa-miR-1179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-23 7.02E-20 1.20E-22 1.10E-21 61 1115 "WDR35,ARHGAP5,FAM193A,ASCL1,TAF1B,CD1D,PCDH9,PCK2,PDE4D,CENPC,VIT,ZNF595,GPR180,ITGBL1,CPNE6,THAP6,PMCH,GNPTAB,THTPA,LYSMD3,SNCAIP,VCAN,UBXN2A,ZNF586,SPATA18,SREK1,DMXL1,RABGAP1L,PARPBP,PPP2R3C,NR1H4,RASA1,RGS4,PACRGL,RNF4,UGT2A3,ELF1,DRAM1,CWC27,TOMM40L,GORAB,POLK,SLC8A1,ARHGEF40,FSHR,MYT1L,CIDEB,PDS5B,PPARGC1A,GJB2,TMED2,METAP2,ADGRA3,GUF1,SLAIN1,KCNT2,ZMYM2,SDR39U1,DIAPH3,RMST,NUAK2" MicroRNA hsa-miR-920:mirSVR_lowEffct hsa-miR-920:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-23 7.22E-20 1.23E-22 1.13E-21 81 1927 "LRRC43,MDM4,ADD1,ULK1,HOMEZ,PPFIA4,UVSSA,APAF1,ZNF784,NOP14,FAM193A,ZNF542P,ATP2B4,LINC02347,NOVA1,NRL,SNTG2,ZNF664,CDK17,CDK18,CCDC122,PIK3C2B,PITX1,PTPRVP,TAPT1,TOGARAM2,SNCAIP,C12orf65,KIAA0040,IFT172,PIGG,COG3,SLC35F6,LINC01257,DTD2,LAP3,SETDB2,LRPPRC,LGR6,STX2,FAM81B,F7,F10,ELOVL7,PCBD2,RELL1,POLK,SUCO,SLC30A6,STPG4,C1orf112,MRPS14,EFR3B,MRPS27,RBKS,METAP2,LILRB4,TCF7,KHNYN,RNF212,RNF17,TEP1,TGM1,ZBTB49,AP4S1,ARHGAP30,GUF1,CENPH,ZFHX2,PLB1,NPHS2,KCNJ9,ANKDD1B,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,LINC00442,RMST,NUAK2,SPRYD7" MicroRNA hsa-miR-508-3p:mirSVR_highEffct hsa-miR-508-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-23 7.41E-20 1.26E-22 1.16E-21 55 902 "MAP1B,SMIM15,WDR35,ASTN1,NLRP4,STARD13,KCTD12,NOVA1,AMDHD1,PCK2,CFL2,PGGT1B,THAP6,HOMER1,COPA,HEATR5A,ITSN2,LRRTM2,DNM3,ZFYVE16,SREK1,PTGS2,CEP350,PARPBP,PPP2R3C,C14orf119,RGS12,MPHOSPH9,LGR6,ARSK,CWC27,CLIP1,N4BP2L2,POLK,BRMS1L,NUBPL,LIMCH1,UHRF1BP1L,KLHL20,ADGRL3,TDG,CRB1,RAB2B,MAEL,HEXB,WDR36,KCNT2,PLB1,ZNF140,ZMYM2,LHX9,DIAPH3,SPRYD7,LMNB1,LOX" MicroRNA hsa-miR-624:mirSVR_lowEffct hsa-miR-624:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-23 7.50E-20 1.28E-22 1.17E-21 78 1798 "WDR35,CUL4A,MSH2,WDR19,ASCL1,SLC4A4,ZNF542P,ATP2B4,KCTD12,ARHGEF7,SLC5A6,NRL,UHMK1,PDE4D,CCDC122,CFAP54,NUP37,LTB4R,FAM163A,TAPT1,POLE,GNPTAB,SNCAIP,CSNK1G3,FAM169A,DCAF8,MATR3,PIGG,F11R,RABGAP1L,SUPT7L,ZNF329,MEMO1,NTN4,STX2,DRAM1,ABCA11P,CLIP1,FCAR,UTP15,TOMM40L,FLT3,STAB2,SLC34A2,DDX51,MBIP,THADA,TMEM132D,DCAF11,MYO16,HSPH1,NEDD1,PCDH17,MAST4,LINC02393,TCF7,RNF212,RNF17,TEP1,AP4S1,BAZ1A,MAEL,ZNF721,ADAMTS19,GUF1,UGT2B7,TENT2,DCP2,KCNT2,SELENOI,SPTSSA,TDRD3,FAM49A,CHPT1,KIF2A,DIAPH3,EP400P1,IFT88" MicroRNA hsa-miR-3147:mirSVR_lowEffct hsa-miR-3147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-23 8.70E-20 1.48E-22 1.35E-21 65 1271 "RALGAPA1,MDM4,WDR35,EP400,ZNF784,FAM193A,CENPBD1P1,SLC4A4,PPP1R12B,FGFRL1,CD84,CCNA1,NOVA1,NRL,RILPL1,CHD1,SLC25A3,MRPL57,CPNE6,HECTD1,NOS1AP,PIGG,PXMP2,C14orf119,TSEN15,FAM129A,AASDH,RGS12,GUSBP3,EIF2B1,ELF1,DLEU1,ABCA11P,ELOVL7,PCBD2,FCGR3A,TOMM40L,FOXG1,FLT1,FMO1,FBXO11,CCDC92,SLC8A1,THADA,POTEM,C1orf112,SNRPF,KIF21B,PDS5B,KDM5B,SRP72,LRCH1,PPARGC1A,UTP20,ADGRA3,SNRNP35,HEXB,ARHGAP30,TECRL,HSD17B4,VRK2,ZNF324B,TMEM178A,AMTN,LCP1" MicroRNA hsa-miR-92a-1*:mirSVR_lowEffct hsa-miR-92a-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-23 9.28E-20 1.58E-22 1.44E-21 69 1430 "MDM4,SLAMF6,NYNRIN,ADCY4,BLZF1,FAM193A,NCOA1,CENPBD1P1,CCNA1,ADGRD1,NOVA1,NRL,PCK2,CDK18,PDGFRA,CHD1,SLC25A3,MRPL57,EPN1,THAP6,FAM169A,DNM3,DDX59,PTPRC,SMC6,AASDH,LAP3,RNF4,MBNL2,DCUN1D2,EIF2B1,ELF1,DHRS2,PCBD2,TOMM40L,SPON2,LRRN2,PIBF1,PEAR1,STAB2,SUPT20H,G2E3,CCDC92,SLC8A1,TMEM132D,C1orf112,SLC22A4,MEGF10,KDM5B,NMNAT2,ZNF274,MAST4,KHNYN,NCSTN,TECRL,GUF1,PAPPA2,ZNF324B,PLB1,SPTSSA,ANKS1B,ZMYM2,LMLN,AMTN,MFSD2B,LCP1,LINC00442,AXDND1,SKA3" MicroRNA hsa-miR-187*:mirSVR_highEffct hsa-miR-187*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-23 9.67E-20 1.64E-22 1.50E-21 53 839 "RALGAPA1,KIAA1211,SLC4A4,PNP,ODC1,FCHO2,UHMK1,PCDH9,DCLK1,CDK17,PDGFRA,CENPC,CFL2,PFKFB2,ZNF595,PGGT1B,WDFY2,COLEC11,ATAD2B,CRHBP,LACC1,GLT8D2,ZNF586,SACS,NR1H4,B3GLCT,ATG10,RB1,RGS4,MPHOSPH9,STK32B,PCGF3,TMEM129,FCGR3A,FCGR3B,FNIP1,FBXO11,NBEA,SF3B6,MYO16,MYT1L,GABRB1,NAAA,ANKLE2,C5orf56,TDG,TFDP1,ZBTB49,TMPO,TRPC4,STARD4,TPTE2,ZMYM2" MicroRNA hsa-miR-363*:mirSVR_lowEffct hsa-miR-363*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-23 1.12E-19 1.90E-22 1.74E-21 74 1640 "MAP1B,ADD1,COG6,UVSSA,ZNF784,FAM193A,ATP1A2,CARMIL3,CD84,CBLN3,RILPL1,RGSL1,CCDC122,HECTD1,PTPRVP,THAP6,C1orf116,BRI3BP,DNM3,FCRL5,BIVM,SPATA18,NOP9,RABGAP1L,LINC01257,TSEN15,FAM129A,RNF31,SMC6,RGS12,POLR1D,RNF4,FCAMR,STX2,ARSK,MAEA,ABCA11P,FCAR,SLC34A2,NBEA,ARHGEF40,ACIN1,DCAF11,KIF21B,JPH4,IQGAP2,NPAS3,NFASC,DRC1,ZNF544,MTUS2,ARHGEF28,KMT5A,COX18,FCRLA,ZBTB49,ACTR6,TPO,LTB4R2,GUF1,UGT2B7,PAPPA2,WDR36,NSD2,MZF1,ANKS1B,PGAM5,LHX9,FIP1L1,NUAK2,TTC7A,AXDND1,PABPN1,ZNF304" MicroRNA hsa-miR-514b-5p:mirSVR_highEffct hsa-miR-514b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-23 1.15E-19 1.95E-22 1.79E-21 60 1089 "MDM4,KCTD12,NOVA1,CD1D,FCRLB,WDFY2,SNX6,PREPL,CSNK1G3,NOS1AP,ZNF586,NUDT12,SACS,WDR1,RASA1,TMEM161B,REST,LAP3,UGT2A3,LGR6,TBC1D19,STX2,CWC27,MAEA,PCGF3,CLIP1,GORAB,FOXG1,NBEA,IVNS1ABP,THADA,CCDC88A,CMPK2,RBKS,LRCH1,KLHL20,PCDH17,BRD8,MAST4,PSME4,UTP20,INSM2,ADGRL3,TCF7,DOCK9,TDG,NPL,HEXB,UBE2K,GUF1,TENT2,YTHDC2,JCHAIN,SPTSSA,ANKS1B,ZMYM2,FAM49A,AXDND1,LMNB1,MICU2" MicroRNA hsa-miR-642:mirSVR_highEffct hsa-miR-642:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-23 1.24E-19 2.08E-22 1.91E-21 57 982 "NYNRIN,HOMEZ,DDX55,PNP,CACNA1E,PCCA,PCDH9,PDGFRA,PGGT1B,SNX6,LTB4R,POU2F1,SNCAIP,BRI3BP,C12orf65,FAM169A,ZNF586,PTGS2,WDR1,C14orf119,DNMT3A,SMC6,RGS4,SETDB2,PACRGL,ELF1,KLHL12,MARVELD2,CWC27,ABCA11P,FCGR2B,FCGR3B,MROH9,UFM1,WDCP,YPEL5,LIMCH1,GABRB1,TMEM183A,SRP72,DRC1,ERBIN,PPARGC1A,PSME4,CRB1,TGFBI,RASSF6,HAL,HEXB,ADAMTS19,HSP90B1,HSD17B4,IL6ST,ZBED3-AS1,CHPT1,LMNB1,SKA3" MicroRNA hsa-miR-548b-5p:PITA hsa-miR-548b-5p:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548c-5p:PITA hsa-miR-548c-5p:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548d-5p:PITA hsa-miR-548d-5p:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548j:PITA hsa-miR-548j:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548a-5p:PITA hsa-miR-548a-5p:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548i:PITA hsa-miR-548i:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-548h:PITA hsa-miR-548h:PITA_TOP PITA 2.39E-23 1.27E-19 2.12E-22 1.94E-21 53 844 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,CCNB1,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-376b:mirSVR_highEffct hsa-miR-376b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.46E-23 1.31E-19 2.18E-22 1.99E-21 63 1204 "MDM4,TMEM132B,APC,CDKL4,STARD13,AMDHD1,CD1D,UHMK1,PCCA,PDGFRA,PGGT1B,GPR180,ITGBL1,NRXN1,LINC01085,BOD1L1,CSNK1G3,LRRTM2,PRKD1,COG3,TBC1D4,OCIAD1,TINF2,DNMT3A,ATG10,EIF2B1,ZNF671,CWC27,ELOVL7,FGF9,POLK,HSD17B7,SLC34A2,FBXO11,PAICS,GFM2,SCYL2,CCDC88A,YPEL5,GABRA2,PDS5B,HSPH1,SRP72,GC,IKBIP,ZNF544,TMED2,NT5C1B,GTF2H3,UBE2K,TXK,ZNF550,VRK2,KCNT2,ZNF84,ANKS1B,ZMYM2,FAM151B,ZBED3-AS1,SPRYD7,LIG4,IFT88,LOX" MicroRNA hsa-miR-600:mirSVR_highEffct hsa-miR-600:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-23 1.46E-19 2.42E-22 2.22E-21 56 950 "MDM4,BIRC6,MSH2,BLZF1,ARL1,NOVA1,SCFD2,PCSK1,PDGFRA,ATAD2B,TAPT1,GNPTAB,SYCP3,SNCAIP,CSNK1G3,TTC37,DMXL1,RABGAP1L,SUPT7L,C14orf119,FAM129A,CLIP4,LRPPRC,EFNA5,IRF9,FCGR3B,FGF9,SDC1,FOXG1,FOXO1,NBEA,STPG4,SCYL2,TADA1,CCDC88A,PKD2L2,MYT1L,KDM5B,GAK,ERBIN,TMED2,COX7B2,ADGRA3,C5orf56,TDG,TMPO,MAEL,ATP6V0A2,UBE2K,TXK,C12orf73,SPTSSA,ANKS1B,SPRYD7,CDK2AP1,ZNF304" MicroRNA hsa-miR-3167:mirSVR_highEffct hsa-miR-3167:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.11E-23 1.66E-19 2.74E-22 2.51E-21 61 1134 "TMEM132B,SLAMF6,ATP6V1G3,SEMA6A,SNX24,AACS,CAST,CHD1,WDFY2,ITGBL1,SNCAIP,COG3,TBC1D4,F11R,TINF2,GNPDA2,PARPBP,B3GLCT,CLIP4,ZNF419,SETDB2,TXNDC15,MARVELD2,CWC27,MAEA,ABCA11P,TOMM40L,SULT6B1,VEZT,NUBPL,SLC30A6,IVNS1ABP,THADA,TADA1,SLC15A4,YPEL5,CYP1B1-AS1,GABRA2,PDS5B,NAAA,CD244,MRPS27,TDG,FCRLA,LINC01551,RASSF6,TMPO,RIMBP2,ZNF721,HAL,HEXB,TXK,ZNF876P,STARD4,DCP2,YTHDC2,SPTSSA,ZMYM2,LHX9,TTC41P,LOX" MicroRNA hsa-miR-541*:mirSVR_highEffct hsa-miR-541*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.12E-23 1.66E-19 2.74E-22 2.51E-21 69 1445 "MDM4,ADD1,NLN,ANKRD34B,AACS,B4GALT3,KCTD12,CD1E,PAH,SLC5A8,PCDH9,ZMYM5,CDK18,PDGFRA,GPR180,TM9SF2,THAP6,TAPT1,VCAN,CEP135,PRKD1,ZNF586,ZFYVE16,COG3,NUDT12,TINF2,ARGLU1,TMEM161B,RGS12,ZNF419,RNASEL,KLHL12,TBC1D19,PCGF3,SH3YL1,FCGR3A,FNIP1,VEZT,SCYL2,SLC8A1,GABRA2,GABRB1,KDM5B,HSPH1,SRP72,RBKS,PCDH17,NMU,PPARGC1A,GJA3,BRD8,INSM2,RNF17,TEP1,TMPO,HEXB,VRK2,HTR2A,SPTSSA,ANKS1B,IRF1,FAM151B,CHPT1,KIF2A,DIAPH3,MFSD2B,LINC01913,SPRYD7,AXDND1" MicroRNA hsa-miR-487a:mirSVR_lowEffct hsa-miR-487a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.12E-23 1.66E-19 2.74E-22 2.51E-21 74 1651 "MDM4,COG6,RGS5,APAF1,APC,AACS,NCOA1,NOVA1,MPZL1,CHAMP1,NFXL1,PCCA,RGSL1,PDGFRA,CENPC,ZNF595,GPR180,PIGR,PKP1,THAP6,HOMER1,AKAP6,SYCP3,CLOCK,FCRL5,FCRL2,SREK1,PTPRC,RABGAP1L,SUPT7L,PPP2R3C,SLC9C2,RGS4,SETDB2,PACRGL,RNASEL,MBNL2,LGR6,MARVELD2,CWC27,PCGF3,PCBD2,PIBF1,FLT3,HSD17B7,FBXO11,NBEA,NUBPL,SLC8A1,PKD2L2,N4BP2,MEGF10,GABRB1,TMEM183A,HSPH1,OXGR1,KDM3B,IKBIP,MAST4,SCFD1,CNTN2,ADGRA3,GPR12,STON1,FZD10,MAEL,SELENOI,CCDC190,ZBTB41,FIP1L1,SPRYD7,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-1267:mirSVR_highEffct hsa-miR-1267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.14E-23 1.67E-19 2.75E-22 2.52E-21 58 1024 "BIRC6,KIAA1211,SNX24,APC,ARHGAP5,AACS,STARD13,FCRLB,PIGR,HECTD1,AKAP6,GNPTAB,POU2F1,LYSMD3,CLOCK,CSNK1G3,UBXN2A,PRKD1,FCRL2,ZNF586,ZFYVE16,SREK1,PTPRC,NR1H4,GUSBP3,MPHOSPH9,ABCA11P,ADGRV1,UTP15,N4BP2L2,PIBF1,SUCO,VEZT,UFM1,ARHGEF40,CCDC88A,N4BP2,C1orf112,MYT1L,NPAS3,SRP72,NEDD1,ZBTB37,PPARGC1A,TMED2,ZBTB49,GTF2H3,HAL,TENT2,IL6ST,ZNF140,ANKS1B,CHPT1,KCNN2,FIP1L1,CAB39L,KIR2DL4,SKA3" MicroRNA hsa-miR-92a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.39E-23 1.80E-19 2.97E-22 2.72E-21 68 1407 "ABL2,MAP1B,RGS5,WDR19,CCDC181,ATP2B4,BTF3,CAD,FCHO2,CCNB1,SCARB1,XPR1,SLC25A3,PITX1,HECTD1,POLE,TTC37,ZFYVE16,IFT172,COG3,DMXL1,KLHL3,F11R,G3BP2,SUPT7L,WDR1,NR1H4,FAM129A,RASA1,IPO4,TMEM33,EFNA5,TXNDC15,RNF4,TRIM28,DNAJC27,TRAPPC13,PCBD2,FNIP1,RASA3,G2E3,BRMS1L,SCYL2,PDS5B,GAK,ERAP1,HSPH1,KDM3B,ANKLE2,LPIN1,ATP11A,GOLGA3,DOCK9,KHNYN,COX18,GTF3C2,ZNF721,HSP90B1,HMGCR,GUF1,SLAIN1,NSD2,DCP2,ZNF84,IL6ST,FAM49A,LETM1,PABPN1" MicroRNA hsa-miR-125a-3p:mirSVR_highEffct hsa-miR-125a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.59E-23 1.91E-19 3.14E-22 2.88E-21 60 1100 "MATN3,LRRC43,HOMEZ,CUL4A,MCFD2,BLZF1,ARL1,NOP14,NRL,CAST,MORN2,LDB2,PCCA,WDFY2,ATAD2B,HOMER1,MPC2,POU2F1,SNCAIP,UBXN2A,ZNF586,SNX17,COCH,OCIAD1,NR1I3,ARGLU1,AASDH,DTD2,RGS4,MBNL2,FAM172A,ABCA11P,ADGRV1,FCGR2B,NDUFAF7,TNFRSF19,PIBF1,SELP,G2E3,SLC8A1,SLC15A4,CHFR,GABRA2,ERAP1,NPAS3,IKBIP,KLHL20,ZBTB37,MAST4,ZNF544,RASSF6,DCP2,JCHAIN,IL6ST,SPTSSA,ANKS1B,LHX9,ZBED3-AS1,CHPT1,KIF2A" MicroRNA hsa-miR-1206:mirSVR_highEffct hsa-miR-1206:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.62E-23 1.92E-19 3.16E-22 2.89E-21 58 1027 "BIRC6,NLN,SEMA6A,APC,BLZF1,WDR19,STXBP6,NCOA1,CENPBD1P1,SLC4A4,CD84,BTF3,NOVA1,CACNA1E,PCDH9,PCK2,RGSL1,RCHY1,CSNK1G3,CEP135,PRKD1,EGLN3,RB1,POLR1D,NTN4,TBC1D19,ARSK,CWC27,ABCA11P,F7,ELOVL7,PEAR1,UFM1,ZNF605,POTEM,P2RX2,NR5A2,ZNF667,CYP1B1-AS1,KIF21B,UHRF1BP1L,OXGR1,SRP72,PPARGC1A,UTP20,ADGRL3,STON1,KMT5A,GTF2H3,ADAMTS19,HSP90B1,ZNF26,KCNT2,LINC00272,FIP1L1,AXDND1,LMNB1,SKA3" MicroRNA hsa-miR-629:mirSVR_lowEffct hsa-miR-629:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.13E-23 2.20E-19 3.60E-22 3.30E-21 71 1534 "SNX24,BLZF1,FCRL3,CBLN3,MPZL1,AMDHD1,RFLNA,ZNF664,ZMYM5,PIWIL1,RCBTB2,CHD1,MRPL57,TM9SF2,SNX6,POLN,TAPT1,ITSN2,PRKD1,ZFYVE16,DCT,FBXL5,NUDT12,CEP120,SUPT7L,NTN4,DHRS2,TBC1D19,FAM172A,DRAM1,ARSK,FAM81B,ETF1,TMEM156,SUCO,FLT1,SLC34A2,FBXO11,BRMS1L,IVNS1ABP,TADA1,CCDC88A,SLC12A2,EFR3B,LIMCH1,MYO16,TMEM183A,ERAP1,ATP8A2,OXGR1,MRPS27,ERBIN,IKBIP,PCDH17,PSME4,GOLGA3,CNTN2,TFDP1,CRB1,LINC01551,BAZ1A,RASSF6,ATP6V0A2,NPL,SLAIN1,IGF1,ZNF84,SELENOI,LHX9,FAM49A,TTC41P" MicroRNA hsa-miR-670:mirSVR_lowEffct hsa-miR-670:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.29E-23 2.28E-19 3.73E-22 3.42E-21 76 1745 "ACOX3,TBC1D14,APBB2,SLC4A4,BCL2L2,NFATC4,NOVA1,CBLN3,CAST,CD1D,PCCA,XPR1,CFL2,CHD1,PFKFB2,NRXN1,PIK3C2B,PKP1,FAM163A,POLE,LYSMD3,CSNK1G3,ITSN2,LRRTM2,FAM169A,UBXN2A,WDR1,DNMT3A,GALNT14,TMEM161B,OGFOD2,MEMO1,RNASEL,TXNDC15,DRAM1,CWC27,TNFRSF19,SUPT20H,VEZT,NLRP2,ZNF605,CGREF1,NR5A2,KIF21B,MIMT1,AURKC,PPARGC1A,GJA3,ZNF544,TBC1D1,UGT2A1,ADAM17,RIPK3,DOCK9,NCSTN,GRSF1,RASSF6,RAB2B,ATP6V0A2,ADAMTS19,NSD2,YTHDC2,ZNF10,SPTSSA,CCDC190,ZBTB41,LHX9,ANKDD1B,FIP1L1,LAD1,LCP1,RMST,SPRYD7,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-1228:mirSVR_lowEffct hsa-miR-1228:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.44E-23 2.36E-19 3.86E-22 3.53E-21 73 1619 "RALGAPA1,NYNRIN,ZNF784,BLZF1,AACS,STARD13,ATP7B,LINC02347,PNP,CAST,CD1D,SNTG2,ZMYM5,FAM177A1,CDK17,CPNE6,ATAD2B,THAP6,LYSMD3,CLOCK,LACC1,NOS1AP,PARPBP,C14orf119,RNF219,ZNF329,MEMO1,PACRGL,EFNA5,DHRS2,STX2,GP6,FAM172A,DRAM1,CWC27,MAEA,PCBD2,UTP15,POLK,PEAR1,MROH9,DDX51,NUBPL,SLC30A6,STPG4,ZNF605,CGREF1,NR5A2,UGGT2,LIMCH1,DCAF11,MYT1L,GABRB1,NPAS3,NFASC,IKBIP,UTP20,ADGRA3,ANO4,ARHGEF28,CRB1,BAZ1A,ADAMTS19,UBE2K,NSD2,ZNF84,ANKS1B,KCNJ9,LINC00442,LETM1,RMST,IFT88,ZNF304" MicroRNA hsa-miR-124:mirSVR_highEffct hsa-miR-124:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.51E-23 2.40E-19 3.91E-22 3.58E-21 60 1105 "BIRC6,NYNRIN,SEMA6A,UVSSA,CDKL4,CCNA1,RILPL1,FCHO2,SLC5A8,PCDH9,FAM177A1,DHRS1,COLEC11,NRXN1,ATAD2B,JAKMIP1,AKAP6,COPA,CLOCK,SNCAIP,VCAN,ITSN2,PRKD1,ZNF586,SREK1,FBXL5,OCIAD1,G3BP2,FAM129A,RGS12,CLIP4,PACRGL,ELK3,ZNF219,DLEU1,SUCO,G2E3,ALKAL2,ZNF605,SLC15A4,SLC22A5,ZNF667,LIMCH1,IQGAP2,SRP54,ANKLE2,PCDH17,GJB2,PPIP5K2,METAP2,GOLGA3,ANO4,AP4S1,HEXB,ADAMTS19,TADA2B,KIF2A,DIAPH3,LINC01913,AXDND1" MicroRNA hsa-miR-23b*:mirSVR_lowEffct hsa-miR-23b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.72E-23 2.51E-19 4.08E-22 3.74E-21 60 1106 "LRRC43,HOMEZ,PPFIA4,AACS,ASTN1,SLC4A4,CADM3,RAB29,FCRLB,RGSL1,CFL2,JAKMIP1,C1orf116,STRN3,POLE,TOGARAM2,LYSMD3,NGDN,LACC1,KIAA0040,DMXL1,PTPRH,MTX3,DHFR,SUPT7L,TSEN15,RAN,CLIP4,CRYL1,LRPPRC,PACRGL,KLHL12,LGR6,ABCA11P,TMEM156,UTP15,TOMM40L,TNFRSF19,CCDC88A,P2RX2,C1orf112,MEGF10,RAPGEF6,LRCH1,ATP11A,PPIP5K2,RNF17,GRSF1,GPR161,LINC01551,IGSF8,TXK,VRK2,GALP,KCNN2,CAB39L,SLAMF9,LINC01913,LMNB1,SKA3" MicroRNA hsa-miR-4264:mirSVR_lowEffct hsa-miR-4264:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-23 2.60E-19 4.23E-22 3.88E-21 72 1580 "MATN3,NLN,SLAMF6,SEMA6A,APC,AACS,ATP2B4,NFATC4,CCNA1,DAOA,CDKL2,CAST,CD1E,SCARB1,UHMK1,PCCA,FAM177A1,CDK7,PDGFRA,CHD1,LINC01085,PIK3C2B,BOD1L1,EPGN,SNCAIP,CMTM5,GLT8D2,OCIAD1,GNPDA2,DNMT3A,ZNF256,ABCA11P,ADGRV1,F7,SLC22A17,SH3YL1,USP44,NDUFAF7,GORAB,N4BP2L2,TNFRSF19,SGCG,TM9SF1,FBXO11,DDX51,MBIP,SLC12A2,SLC22A5,UGGT2,MEGF10,GABRA2,HSPH1,CMPK2,LRCH1,ADGRL3,CRB1,AP4S1,GTF2H3,ACTR6,RAB2B,RIMBP2,ADAMTS19,TECRL,TENT2,NSD2,ZMYM2,LHX9,TDRD3,ZBED3-AS1,RILPL2,IFT88,ZNF304" MicroRNA hsa-miR-221*:mirSVR_lowEffct hsa-miR-221*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.91E-23 2.61E-19 4.24E-22 3.88E-21 79 1879 "CUL4A,APAF1,APC,DDX55,NOP14,AACS,ASTN1,SLC4A4,ZNF542P,ATP2B4,ATP4B,ATP7B,NFATC4,CAST,SCARB1,ZNF664,PCDH9,PDE4D,PDGFRA,CHD1,MRPL57,JAKMIP1,POLN,PTPRVP,TAPT1,NGDN,LRRTM2,CEP350,GNPDA2,GALNT14,FAM129A,B3GLCT,RGS12,PACRGL,KLHL12,DHRS2,TCTN2,STX2,DRAM1,STK32B,ADGRV1,PCBD2,TMEM129,FCAR,LRRN2,TNFRSF19,TACC3,PIBF1,POLK,FTLP10,G2E3,GFM2,IVNS1ABP,SLC8A1,ARHGEF40,ZNF605,SLC12A2,NAAA,ZNF274,NFASC,DRC1,MCCC2,MTUS2,ADGRL3,C5orf56,TCF7,RNF212,CRB1,AP4S1,GTF3C2,ACTR6,FZD10,ATP6V0A2,STARD4,NSD2,LAD1,LINC00442,LMNB1,ZNF304" MicroRNA hsa-miR-10b:mirSVR_lowEffct hsa-miR-10b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.93E-23 2.62E-19 4.25E-22 3.89E-21 69 1457 "TMEM132B,BLZF1,SLC4A4,PNP,DAOA,SNTG2,PDGFRA,CCDC122,PIGR,LINC01085,POLN,THAP6,TOGARAM2,CSNK1G3,CEP135,UBXN2A,EIF2AK2,ZNF586,IFT172,CEP350,SLC35F6,FAM129A,RNF31,TMEM161B,ZNF329,PACRGL,MBNL2,KIRREL1,MARVELD2,TCTN2,BORA,DRAM1,SAP18,ETF1,F7,PCBD2,FCAR,UTP15,GORAB,TNFRSF19,PIBF1,FLT1,SUPT20H,FBXO11,PAICS,STPG4,THADA,SLC12A2,CGREF1,NR5A2,MYT1L,RAPGEF6,MCCC2,ANKLE2,ERBIN,IKBIP,STRN,UTP20,ACSL6,RASSF6,RAB2B,TMPO,HTR2A,YTHDC2,SPTSSA,KCNN2,FIP1L1,MFSD2B,NUAK2" MicroRNA hsa-miR-3118:mirSVR_highEffct hsa-miR-3118:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.01E-23 2.67E-19 4.31E-22 3.95E-21 52 824 "WDR35,BLZF1,NCOA1,FCGR2C,PCDH9,MRPL57,ITGBL1,ADGRF3,THAP6,COPA,LYSMD3,SNCAIP,KIAA0040,FCRL5,SUPT7L,RAN,EGLN3,RB1,DTD2,PACRGL,TBC1D19,ETF1,USP44,N4BP2L2,TNFRSF19,CCDC92,BRMS1L,ZNF605,SLC15A4,CYP1B1-AS1,ERAP1,NPAS3,NFASC,PPARGC1A,PSME4,TMED2,ANO4,ARHGEF28,EML4,RNF212,RNF17,RAB2B,GUF1,ZNF550,SLAIN1,ZNF10,MZF1,ZMYM2,IRF1,CHPT1,AXDND1,LTA4H" MicroRNA hsa-miR-892a:mirSVR_highEffct hsa-miR-892a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.23E-23 2.78E-19 4.50E-22 4.12E-21 56 963 "RALGAPA1,MDM4,COG6,ADCY4,ARL1,SLC4A4,ARHGEF7,BTF3,CACNA1E,FCHO2,PCK2,CDK17,PDGFRA,CHD1,GPR180,ATAD2B,BOD1L1,THAP6,HOMER1,CLOCK,VCAN,C12orf65,TBC1D4,B3GLCT,RNF31,RB1,RGS4,NTN4,PACRGL,ELOVL7,TRAPPC13,FOXG1,SUPT20H,SCYL2,TADA1,CCDC88A,LIMCH1,CYP1B1-AS1,MYO16,FAM114A1,COMMD6,GJB2,TBC1D1,KHNYN,TMPO,HMGCR,STARD4,NSD2,ZNF10,KCNT2,IL6ST,ZNF140,ANKS1B,ZMYM2,LOX,ZNF304" MicroRNA hsa-miR-3118:mirSVR_lowEffct hsa-miR-3118:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.50E-23 2.92E-19 4.71E-22 4.32E-21 73 1625 "MAP1B,BIRC6,ADD1,KIAA1211,MSH2,ARL1,SLC4A4,TAF1B,MPZL1,PCK2,PCSK1,PDE4D,BOD1L1,LTB4R,AKAP6,FAM163A,PM20D1,EPGN,CSNK1G3,VCAN,FAM169A,DNM3,BIVM,SPATA18,COG3,LOC439933,NUDT12,TBC1D4,PARPBP,FAM129A,B3GLCT,RGS4,CRYL1,EFNA5,KIRREL1,MPHOSPH9,TCTN2,ZNF671,FAM81B,F10,FNIP1,SELP,FLT1,SUPT20H,NBEA,UFM1,CCDC88A,WDCP,SLC22A5,MEGF10,PDS5B,TMEM183A,UHRF1BP1L,GJB6,DRC1,LILRB1,ZBTB37,MAST4,TBC1D1,ADGRL3,GTF3C2,MAEL,ADAMTS19,ARHGAP30,ZNF876P,NLRP8,JCHAIN,SELENOI,IL6ST,PLB1,LMLN,FIP1L1,LOX" MicroRNA hsa-miR-151-3p:mirSVR_lowEffct hsa-miR-151-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.04E-23 3.21E-19 5.17E-22 4.73E-21 63 1225 "MAP1B,ACOX3,TBC1D14,STXBP6,CENPBD1P1,NFATC4,PDE4D,PDGFRA,CFAP54,ATAD2B,LTB4R,STRN3,MPC2,RCHY1,FAM169A,DNM3,FCRL5,FBXL5,NUDT12,CEP120,F11R,PTPRH,SLC35F6,TSEN15,RAN,EGLN3,RNF31,RGS12,LRPPRC,TXNDC15,SPATA9,SNORA53,ELK3,ZNF671,GMPR2,TLR6,RELL1,POLK,MROH9,FLT3,UFM1,SLC8A1,TADA1,CGREF1,NR5A2,MEGF10,GABRA2,PDS5B,UHRF1BP1L,IKBIP,TMED2,ARHGEF28,DOCK9,RNF17,GRSF1,TFDP1,ATP6V0A2,ADAMTS19,ZNF470,LINC01913,SPRYD7,AXDND1,ZNF304" MicroRNA hsa-miR-1265:mirSVR_highEffct hsa-miR-1265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.44E-23 3.43E-19 5.51E-22 5.04E-21 54 897 "NLN,SLAMF6,COG6,WDR35,APAF1,WDR19,KCTD12,NOVA1,CAMK4,CAST,PDE4D,PDGFRA,PFKFB2,LINC01085,MPHOSPH8,SPATA18,COG3,CEP350,GNPDA2,SMC6,DTD2,GRTP1,CWC27,GMPR2,F7,F10,SH3YL1,FNIP1,N4BP2L2,FGF9,POLK,SUPT20H,BRMS1L,NLRP2,TADA1,PKD2L2,LIMCH1,PDS5B,CMPK2,SRP54,ADGRL3,ANO4,FCRLA,TEP1,GTF2H3,GTF3C2,RAB2B,YTHDC2,ZNF10,TADA2B,IL6ST,ZBTB41,LINC00272,PGAM5" MicroRNA hsa-miR-549:mirSVR_lowEffct hsa-miR-549:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.93E-23 3.69E-19 5.91E-22 5.42E-21 69 1466 "MATN3,IL17D,MDM4,SLAMF6,ANKRD34B,SEMA6A,SNX24,FAM193A,ATP4B,NEDD8,LINC02347,ADGRD1,PNP,CACNA1E,MPZL1,FCHO2,NFXL1,SNTG2,ZMYM5,XPR1,CDK17,VIT,GPR180,ITGBL1,SMIM14,SNX6,BOD1L1,POLE,C12orf65,DNM3,KIAA0040,C14orf119,RNF219,NR1H4,SLC9C2,NTN4,GRTP1,DLEU1,ADGRV1,F7,SPON2,N4BP2L2,PIBF1,MROH9,BRMS1L,NUBPL,UFM1,SLC8A1,SLC12A2,TMEM132D,EFR3B,GABRA2,PDS5B,NAAA,NPAS3,NEDD1,LRCH1,NMU,KMT5A,GRSF1,TFDP1,ARHGAP30,C12orf73,LHX9,LMLN,DIAPH3,KIR2DS4,IFT88,PABPN1" MicroRNA hsa-miR-2116*:mirSVR_lowEffct hsa-miR-2116*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.27E-23 3.87E-19 6.20E-22 5.67E-21 72 1591 "EP400,MCFD2,WDR19,BCL2L2,BTF3,NRL,MPZL1,CAST,CHAMP1,LDB2,CD1E,SNTG2,PCCA,ZMYM5,WDFY2,PKP1,THAP6,GNPTAB,SNCAIP,NOS1AP,DCAF8,DMXL1,FBXL5,CEP350,F11R,PTPRH,RABGAP1L,DHFR,PARPBP,C14orf119,TMEM161B,OGFOD2,RGS4,KIRREL1,MARVELD2,FCAMR,EFS,FGFR3,PEAR1,HSD17B7,NUBPL,TADA1,PKD2L2,TMEM132D,SLC22A4,NR5A2,RAPGEF6,NFASC,MCCC2,IKBIP,DHRS4,GOLGA3,ARHGEF28,KMT5A,XPO4,RNF17,TEP1,HAL,IGSF8,NPL,TPO,KLF12,UBE2K,NLRP8,PAPPA2,VRK2,ZFHX2,ZNF470,LMLN,AXDND1,LMNB1,ZNF304" MicroRNA hsa-miR-33b:mirSVR_highEffct hsa-miR-33b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.32E-23 3.89E-19 6.23E-22 5.70E-21 53 865 "MATN3,ATP6V1G3,MSH2,BLZF1,KCTD12,NFATC4,CAMK4,FCHO2,PCCA,PDE4D,CHD1,LINC01085,SNX6,THAP6,HOMER1,AKAP6,VCAN,PRKD1,ZFYVE16,SPATA18,SREK1,LOC439933,PTPRC,GNPDA2,EGLN3,RASA1,LAP3,RGS12,TMEM33,NTN4,GUSBP3,PACRGL,TXNDC15,ARSK,DLEU1,TRAPPC13,PIBF1,FMO1,FSHR,YPEL5,NAAA,ERAP1,STRN,ZNF544,PPIP5K2,STON1,CRB1,LINC01551,HMGCR,ZNF140,KIF3C,RMST,LIG4" MicroRNA hsa-miR-520a-5p:mirSVR_highEffct hsa-miR-520a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.33E-23 3.90E-19 6.23E-22 5.70E-21 58 1042 "SLC4A4,PPP1R12B,NEDD8,NOVA1,SCARB1,SLC5A8,CFL2,CHD1,PFKFB2,SNX6,PKP1,THAP6,NGDN,CSNK1G3,ITSN2,LRRTM2,DCAF8,OCIAD1,TINF2,GNPDA2,NR1H4,EGLN3,RB1,RGS4,RNASEL,ELOVL7,USP44,FCGR3A,UTP15,FCGR3B,PIBF1,HSD17B7,STAB2,FBXO11,ZNF605,SLC22A4,MRPS14,PDS5B,UHRF1BP1L,IQGAP2,MRPS27,MAST4,INSM2,ADAM17,CRB1,GTF3C2,TMPO,HEXB,ARHGAP30,SLAIN1,IGF1,PLB1,ZMYM2,KIF2A,RMST,ZDHHC20,LMNB1,PABPN1" MicroRNA hsa-miR-302b:mirSVR_highEffct hsa-miR-302b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.50E-23 3.99E-19 6.36E-22 5.82E-21 70 1509 "MDM4,KIAA1211,B4GALT3,ATP7B,ARHGEF7,CCNA1,FCRLB,RFLNA,ZNF664,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,SNCAIP,C12orf65,ITSN2,CEP135,SPATA18,DMXL1,NUDT12,TBC1D4,RABGAP1L,GNPDA2,PARPBP,IPO4,CLIP4,NTN4,LRPPRC,RNASEL,LATS2,SNORA53,MPHOSPH9,STX2,DRAM1,DNAJC27,IRF9,FCGR2B,RELL1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,ARHGEF40,YPEL5,MYT1L,CENPJ,ZBTB37,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,RNF212,TDG,CRB1,ARHGAP30,C12orf73,KCNN2,LIG4,IFT88,LTA4H" MicroRNA hsa-miR-507:mirSVR_highEffct hsa-miR-507:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.17E-23 4.35E-19 6.92E-22 6.34E-21 57 1008 "MATN3,ULK1,CUL4A,WDR19,NCOA1,FCRL3,CDKL2,CAMK4,PCDH9,CDK7,PGGT1B,SLC25A3,ITGBL1,NRXN1,NUP37,THAP6,HOMER1,AKAP6,FCRL5,FCRL2,GLT8D2,SREK1,COG3,DMXL1,RB1,POLR1D,CRYL1,SETDB2,GP6,STK32B,ABCA11P,TNFRSF19,FOXO1,FLT1,SCYL2,TADA1,GABRA2,NAAA,LRCH1,PCDH17,DHRS4,ADAM17,PPIP5K2,MTUS2,ANO4,LINC01551,ZNF721,HAL,TXK,GUF1,VRK2,JCHAIN,ZNF140,KCNJ9,AXDND1,LMNB1,LOX" MicroRNA hsa-miR-3126-3p:mirSVR_lowEffct hsa-miR-3126-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.29E-23 4.41E-19 7.01E-22 6.42E-21 66 1350 "SFTA3,MAP1B,LRRC43,ADD1,HOMEZ,MSH2,ZNF542P,MYBPC1,FGFRL1,NOVA1,PNP,DAOA,CBLN3,CAST,RILPL1,CD1E,PCCA,FAM177A1,PIK3C2B,AKAP6,GNPTAB,KIAA0040,CMTM5,CEP350,KLHL3,RABGAP1L,DHFR,SUPT7L,NR1I3,RNF31,ZNF329,SMC6,PACRGL,KIRREL1,MARVELD2,FAM172A,FCAR,FCGR3A,FCGR3B,LRRN2,FOXO1,FTLP10,STAB2,G2E3,TMEM132D,SLC22A4,DCAF11,CYP1B1-AS1,GABRB1,KIF21B,ZNF274,NFASC,GJB2,MAST4,ANO4,SLC7A8,GPR161,RAB2B,HSD17B4,VRK2,IL6ST,ZMYM2,ZBED3-AS1,TTC41P,MFSD2B,RMST" MicroRNA hsa-miR-3130-3p:mirSVR_lowEffct hsa-miR-3130-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.39E-23 4.46E-19 7.08E-22 6.48E-21 72 1595 "SMIM15,BIRC6,TMEM132B,NLN,SLAMF6,FBRSL1,ZNF784,WDR19,SLC4A4,ZNF542P,FGFRL1,PNP,CAMK4,RILPL1,FCGR2C,CDK18,COLEC11,MRPL57,CFAP54,POLN,TAPT1,COPA,SNCAIP,VCAN,CEP135,KIAA0040,SPATA18,PIGG,SREK1,WDR1,NR1H4,RAN,GUSBP3,TXNDC15,EIF2B1,STK32B,DLEU1,PCGF3,TMEM156,FCAR,TACC3,FOXG1,HSD17B7,PLEKHA6,ZNF446,THADA,ARHGEF40,C1orf112,DCAF11,NMNAT2,ERAP1,GJA3,TBC1D1,CNTN2,LILRB4,TCF7,DOCK9,RIMBP2,TPO,TECRL,RXFP2,TENT2,CCDC169,PLB1,IRF1,ZBED3-AS1,KIT,RILPL2,LAD1,RMST,ZDHHC20,ZNF304" MicroRNA hsa-miR-4290:mirSVR_lowEffct hsa-miR-4290:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.68E-23 4.62E-19 7.32E-22 6.70E-21 69 1472 "ABL2,SEMA6A,PITPNM2,ARL1,FAM193A,AACS,MYBPC1,CADM3,MYH6,FCRL3,PROZ,NFATC4,ARHGEF7,ADGRD1,CAST,RILPL1,CDK18,RGSL1,PFKFB2,WDFY2,ATAD2B,ADGRF3,LTB4R,PTPRVP,FAM53A,KIAA0040,FCRL5,SREK1,COG3,F11R,SUPT7L,RABGGTA,DNMT3A,OGFOD2,RGS12,SETDB2,PACRGL,EFNA5,GP6,EFS,F7,SLC22A17,FLT3,FTLP10,ZNF605,SLC12A2,POTEM,HSPH1,IKBIP,KLHL20,STRN,MAST4,GOLGA3,ADGRL3,DOCK9,CRB1,TNR,UBE2K,STARD4,CENPH,ZFHX2,GALP,PGAM5,FAM151B,KCNJ9,SLAMF9,AXDND1,LMNB1,PABPN1" MicroRNA hsa-miR-1274b:mirSVR_lowEffct hsa-miR-1274b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.83E-23 4.70E-19 7.43E-22 6.80E-21 60 1120 "SFTA3,ABL2,DHX37,ARL1,ATP4B,STARD13,NOVA1,AMDHD1,NFXL1,PCDH9,CHD1,NRXN1,PKP1,HOMER1,HEATR5A,NCOR2,SNCAIP,CSNK1G3,LRRTM2,UBXN2A,ZFYVE16,COG3,G3BP2,WDR1,PARPBP,OGFOD2,RGS4,KIRREL1,ELF1,GP6,DEPDC4,ARSK,SAP18,F10,NDUFAF7,TNFRSF19,SDC1,FLT3,BRMS1L,PAICS,STPG4,IVNS1ABP,TMEM132D,NMNAT2,NEDD1,ANKLE2,ERBIN,LILRB1,IKBIP,ADGRL3,C5orf56,TCF7,CRB1,IRF1,FAM151B,KCNN2,KIR2DL4,TTC41P,RMST,IFT88" MicroRNA hsa-miR-181b-5p:TargetScan hsa-miR-181b-5p TargetScan 8.97E-23 4.77E-19 7.49E-22 6.85E-21 56 974 "MAP1B,MCC,NDRG2,BIRC6,NLN,CUL4A,ARL1,ASTN1,PPP1R3E,PPP1R12B,NOVA1,CDKL2,CCNB1,DCLK1,PCSK1,CDK17,PDGFRA,CHD1,GPR180,NRXN1,HOMER1,POU2F1,CLOCK,CSNK1G3,CEP135,CEP350,KLHL3,G3BP2,MTX3,RAN,SBNO1,MBNL2,DRAM1,MAEA,CLIP1,FGFR3,FLT1,FBXO11,NBEA,CCDC92,LIMCH1,GABRB1,NMNAT2,IQGAP2,CMPK2,ATP11A,PPIP5K2,METAP2,ACSL6,BAZ1A,RASSF6,HSP90B1,IL6ST,LHX9,FAM49A,LOX" MicroRNA hsa-miR-181d-5p:TargetScan hsa-miR-181d-5p TargetScan 8.97E-23 4.77E-19 7.49E-22 6.85E-21 56 974 "MAP1B,MCC,NDRG2,BIRC6,NLN,CUL4A,ARL1,ASTN1,PPP1R3E,PPP1R12B,NOVA1,CDKL2,CCNB1,DCLK1,PCSK1,CDK17,PDGFRA,CHD1,GPR180,NRXN1,HOMER1,POU2F1,CLOCK,CSNK1G3,CEP135,CEP350,KLHL3,G3BP2,MTX3,RAN,SBNO1,MBNL2,DRAM1,MAEA,CLIP1,FGFR3,FLT1,FBXO11,NBEA,CCDC92,LIMCH1,GABRB1,NMNAT2,IQGAP2,CMPK2,ATP11A,PPIP5K2,METAP2,ACSL6,BAZ1A,RASSF6,HSP90B1,IL6ST,LHX9,FAM49A,LOX" MicroRNA hsa-miR-181a-5p:TargetScan hsa-miR-181a-5p TargetScan 8.97E-23 4.77E-19 7.49E-22 6.85E-21 56 974 "MAP1B,MCC,NDRG2,BIRC6,NLN,CUL4A,ARL1,ASTN1,PPP1R3E,PPP1R12B,NOVA1,CDKL2,CCNB1,DCLK1,PCSK1,CDK17,PDGFRA,CHD1,GPR180,NRXN1,HOMER1,POU2F1,CLOCK,CSNK1G3,CEP135,CEP350,KLHL3,G3BP2,MTX3,RAN,SBNO1,MBNL2,DRAM1,MAEA,CLIP1,FGFR3,FLT1,FBXO11,NBEA,CCDC92,LIMCH1,GABRB1,NMNAT2,IQGAP2,CMPK2,ATP11A,PPIP5K2,METAP2,ACSL6,BAZ1A,RASSF6,HSP90B1,IL6ST,LHX9,FAM49A,LOX" MicroRNA hsa-miR-181c-5p:TargetScan hsa-miR-181c-5p TargetScan 8.97E-23 4.77E-19 7.49E-22 6.85E-21 56 974 "MAP1B,MCC,NDRG2,BIRC6,NLN,CUL4A,ARL1,ASTN1,PPP1R3E,PPP1R12B,NOVA1,CDKL2,CCNB1,DCLK1,PCSK1,CDK17,PDGFRA,CHD1,GPR180,NRXN1,HOMER1,POU2F1,CLOCK,CSNK1G3,CEP135,CEP350,KLHL3,G3BP2,MTX3,RAN,SBNO1,MBNL2,DRAM1,MAEA,CLIP1,FGFR3,FLT1,FBXO11,NBEA,CCDC92,LIMCH1,GABRB1,NMNAT2,IQGAP2,CMPK2,ATP11A,PPIP5K2,METAP2,ACSL6,BAZ1A,RASSF6,HSP90B1,IL6ST,LHX9,FAM49A,LOX" MicroRNA hsa-miR-548c-3p:PITA hsa-miR-548c-3p:PITA_TOP PITA 8.97E-23 4.77E-19 7.49E-22 6.85E-21 62 1196 "MAP1B,TMEM132B,NLN,CUL4A,PITPNM2,ARHGAP5,ARL1,NCOA1,ASTN1,SLC4A4,NFKBIA,ODC1,FCHO2,LDB2,PCSK1,CDK17,PDE4D,PFKFB2,GPR180,ATAD2B,PKP1,AKAP6,CLOCK,LRRTM2,DNM3,MATR3,BIVM,COG3,TBC1D4,CEP120,F11R,G3BP2,MTX3,DNMT3A,EFNA5,MBNL2,ETF1,CLIP1,FNIP1,TNFRSF19,FOXO1,FLT3,FBXO11,SCYL2,SLC12A2,SLC22A5,PDS5B,IQGAP2,KDM3B,ERBIN,PPARGC1A,INSM2,GOLGA3,ADGRL3,STON1,SLC7A8,ADAMTS19,KLF12,HMGCR,IGF1,ZBTB41,RILPL2" MicroRNA hsa-miR-619:mirSVR_lowEffct hsa-miR-619:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.53E-23 5.07E-19 7.95E-22 7.28E-21 74 1683 "RALGAPA1,NYNRIN,SEMA6A,PITPNM2,FBRSL1,MSH2,ZNF542P,NFATC4,ARHGEF7,LINC02347,PNP,CACNA1E,CD1D,SNTG2,PCCA,DCLK1,RGSL1,GLT1D1,CHD1,CCDC122,TM9SF2,PIGR,LTB4R,UGT2B28,PTPRVP,THAP6,VCAN,COG3,F11R,DHFR,ATG10,RGS12,MEMO1,SETDB2,KLHL12,LGR6,EFS,FAM81B,PCGF3,ELOVL7,TOMM40L,FLT1,HSD17B7,G2E3,NLRP2,SLC8A1,SLC12A2,TMEM132D,CYP1B1-AS1,KDM5B,NMNAT2,ZNF274,GJB6,ZBTB37,PPARGC1A,ZNF544,ANO4,GPR12,TCF7,C1QTNF9B,TEP1,RAB2B,ADAMTS19,HMGCR,TADA2B,SPTSSA,ZMYM2,ZBTB41,SDR39U1,KCNJ9,LMLN,LINC01913,LMNB1,CDK2AP1" MicroRNA hsa-miR-331-5p:mirSVR_lowEffct hsa-miR-331-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.58E-23 5.09E-19 7.97E-22 7.30E-21 63 1236 "CUL4A,UVSSA,APAF1,ASTN1,MPZL1,CAST,FCHO2,CHAMP1,FCGR2C,CD1D,PAH,PCDH9,SCFD2,RCBTB2,ITGBL1,NUP37,ATAD2B,THAP6,AKAP6,HEATR5A,CLOCK,DNM3,FCRL2,ZFYVE16,PTPRC,TINF2,PPP2R3C,TMEM33,CLIP4,MEMO1,PACRGL,MBNL2,SNORA53,MARVELD2,DHRS2,GMPR2,CLIP1,SH3YL1,USP44,SELP,TADA1,ZNF605,LIMCH1,CPSF3,GABRB1,NEDD1,IKBIP,GJA3,UGT2A1,SCFD1,CNTN2,RASSF6,ACTR6,NPL,HEXB,ZNF10,ZNF470,IL6ST,SPTSSA,TDRD3,LMLN,LMNB1,LOX" MicroRNA hsa-miR-146a:mirSVR_lowEffct hsa-miR-146a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-22 5.48E-19 8.57E-22 7.84E-21 79 1902 "SFTA3,ADD1,COG6,WDR35,RGS5,PPFIA4,ARL1,FAM193A,LINC02347,CDKL2,AMDHD1,NFXL1,PCDH9,DCLK1,SCFD2,ZNF595,TM9SF2,LINC01085,SNX6,COPA,RCHY1,GALNT9,C12orf65,PIGG,FBXL5,TBC1D4,CEP120,GNPDA2,EGLN3,RASA1,RNASEL,MBNL2,ELF1,ELK3,DHRS2,GP6,EFS,FAM81B,ETF1,ADGRV1,PCGF3,FCAR,UTP15,LRRN2,FLT1,ZCCHC8,PAICS,SLC30A6,ARHGEF40,TADA1,ZNF605,PKD2L2,EFR3B,LIMCH1,PDS5B,GJB6,NPAS3,IKBIP,NMU,CFHR4,STRN,PPIP5K2,LILRB4,RNF212,RNF17,TEP1,TFDP1,RAB2B,RIMBP2,HPCAL1,TENT2,WDR36,ZNF10,KIF3C,KIR2DL1,KIR3DL1,FAM71C,LMNB1,CDK2AP1" MicroRNA hsa-miR-548q:mirSVR_lowEffct hsa-miR-548q:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-22 5.72E-19 8.92E-22 8.17E-21 68 1437 "MCC,SLAMF6,SEMA6A,BLZF1,NCOA1,ARHGEF7,FAM177A1,XPR1,CDK18,VIT,HECTD1,AKAP6,TAPT1,RCHY1,TOGARAM2,THTPA,POU2F1,LYSMD3,CRHBP,DNM3,FCRL5,MATR3,SNX17,SPATA18,PIGG,COCH,GNPDA2,PARPBP,RNF31,RGS12,POLR1D,KLHL12,DHRS2,TBC1D19,DLEU1,PCGF3,ARL6IP4,FGF9,SELP,MROH9,RUBCNL,G2E3,GABRB1,NMNAT2,RAPGEF6,TMEM183A,IQGAP2,ERAP1,KLHL20,PCDH17,PPARGC1A,BRD8,MAST4,LINC02393,C1QTNF9B,RNF17,LINC01551,RIMBP2,TPO,ADAMTS19,UBE2K,ANKS1B,ZBED3-AS1,TMEM178A,FIP1L1,LINC01913,IFT88,ZNF304" MicroRNA hsa-miR-93*:mirSVR_highEffct hsa-miR-93*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-22 5.79E-19 9.02E-22 8.25E-21 56 978 "MDM4,MSH2,BLZF1,STXBP6,AACS,ASTN1,CENPBD1P1,ATP12A,SLC4A4,ARHGEF7,CCNA1,PNP,CACNA1E,SCARB1,PCSK1,CDK18,RGSL1,WDFY2,STRN3,RNASE9,PM20D1,GALNT9,UBXN2A,FCRL5,FCRL2,DCAF8,CEP350,TBC1D4,MBNL2,LGR6,MARVELD2,CWC27,DNAJC27,SULT6B1,LRRN2,SUCO,SUPT20H,IVNS1ABP,N4BP2,PDS5B,NAAA,RBKS,METAP2,STON1,C1QTNF9B,TMPO,TPO,KLF12,IL6ST,ANKS1B,ZBED3-AS1,CHPT1,KIR2DL1,EP400P1,RMST,AXDND1" MicroRNA hsa-miR-3122:mirSVR_lowEffct hsa-miR-3122:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-22 6.03E-19 9.38E-22 8.59E-21 67 1398 "MATN3,TMEM132B,SEMA6A,MCFD2,ARL1,NOP14,ASTN1,CADM3,MYH6,BCL2L2,ARHGEF7,AP1G2,CACNA1E,SYT2,SNTG2,PDGFRA,CHD1,WDFY2,C1orf116,TAPT1,CLOCK,PREPL,SNCAIP,ITSN2,DNM3,FCRL5,LOC439933,NUDT12,PTPRC,OCIAD1,TINF2,FAM129A,AASDH,RNF4,EIF2B1,MARVELD2,CWC27,SAP18,POLK,SUCO,CCDC92,THADA,IQGAP2,MRPS27,CMPK2,ZBTB37,METAP2,KHNYN,C1QTNF9B,XPO4,RNF17,CRB1,AP4S1,GTF2H3,GTF3C2,TECRL,VRK2,WDR36,FCRL6,PLB1,TMEM178A,KCNJ9,LMLN,AMTN,EP400P1,RMST,SPRYD7" MicroRNA hsa-miR-1915:mirSVR_lowEffct hsa-miR-1915:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-22 6.28E-19 9.75E-22 8.93E-21 75 1732 "LRRC43,NDRG2,TMEM132B,EP400,DHX37,PPFIA4,APBB2,DDX55,CENPBD1P1,B4GALT3,ATP7B,BTF3,SLC5A6,SCARB1,FCRLB,SLC5A8,PDE4D,GLT1D1,ZNF595,WDFY2,CPNE6,PIK3C2B,EPN1,THAP6,FAM163A,NGDN,SNCAIP,LRRTM2,FCRL5,SNX17,EPS8L1,PIGG,OCIAD1,TINF2,B3GLCT,RNF31,OGFOD2,TMEM33,RNASEL,DCUN1D2,KIRREL1,LGR6,ZNF219,CWC27,F7,TMEM129,ARHGEF40,TMEM132D,CGREF1,C1orf112,GABRB1,JPH4,TMEM183A,KDM3B,DRC1,IKBIP,ZNF544,TBC1D1,UTP20,RIPK3,NCSTN,FZD10,NPL,HEXB,NSD2,FCRL6,IGF1,PLB1,IRF1,KCNN2,RNASE11,LINC01913,ZDHHC20,PABPN1,ZNF304" MicroRNA hsa-miR-583:mirSVR_highEffct hsa-miR-583:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-22 6.91E-19 1.07E-21 9.81E-21 68 1442 "BIRC6,ANKRD34B,APC,CD84,NEDD8,TAF1B,FCHO2,CD1E,UHMK1,PCDH9,RGSL1,PDGFRA,RCBTB2,CHD1,ADGRF3,SNCAIP,CEP135,PRKD1,FCRL5,NOS1AP,ZNF586,ZFYVE16,IFT172,PSME1,TBC1D4,TINF2,G3BP2,REST,POLR1D,ELK3,FAM172A,ABCA11P,USP44,IRF9,GORAB,SELP,FLT1,FMO1,VEZT,TM9SF1,NBEA,BRMS1L,SLC12A2,PKD2L2,MRPS14,UHRF1BP1L,SRP72,MCCC2,NEDD1,LRCH1,ERBIN,BRD8,EML4,CRB1,GTF3C2,HAL,HEXB,WDR36,IGF1,ZNF470,IL6ST,CHPT1,KIR2DL4,KIT,DNAH10,LMNB1,LOX,EEF1AKMT1" MicroRNA hsa-miR-143:mirSVR_highEffct hsa-miR-143:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.31E-22 6.99E-19 1.08E-21 9.90E-21 62 1205 "WDR35,DHX37,MSH2,CENPBD1P1,CD84,LINC02347,CAST,AMDHD1,CD1E,NFXL1,ZNF664,DCLK1,PDGFRA,WDFY2,GPR180,THAP6,AKAP6,STRN3,COPA,POU2F1,PREPL,CSNK1G3,CEP135,DNM3,FCRL5,EIF2AK2,DCAF8,ZFYVE16,BIVM,SREK1,COG3,DMXL1,NR1I3,DNMT3A,ATG10,RASA1,PACRGL,STK32B,DLEU1,F10,N4BP2L2,FGF9,FOXG1,YPEL5,LIMCH1,GAK,EAPP,SRP72,SULT1E1,PPARGC1A,PSME4,AP4S1,RASSF6,RAB2B,TMPO,MAEL,NPL,TECRL,NLRP8,NSD2,IL6ST,ZMYM2" MicroRNA hsa-miR-1302:mirSVR_lowEffct hsa-miR-1302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-22 7.44E-19 1.15E-21 1.05E-20 70 1526 "MCC,NDRG2,TMEM132B,NLN,EP400,PPFIA4,UVSSA,WDR19,AACS,CENPBD1P1,SLC4A4,CADM3,AP1G2,CACNA1E,CBLN3,MPZL1,RILPL1,ZNF664,AKAP6,SNCAIP,CEP135,DCAF8,SREK1,PTPRC,GNPDA2,SUPT7L,PARPBP,GUSBP3,RNF4,ZNF219,DRAM1,PCBD2,FCGR2B,N4BP2L2,PEAR1,SELP,HSD17B7,UFM1,SLC15A4,PUS1,GABRA2,CENPJ,NPAS3,RBKS,LRCH1,PPARGC1A,MAST4,TBC1D1,ADGRA3,KHNYN,NCSTN,RNF17,TEP1,TFDP1,ZBTB49,AP4S1,UBE2K,TXK,NLRP8,HTR2A,NSD2,ZNF470,CCDC169,PLB1,PGAM5,ZBED3-AS1,FIP1L1,IFT88,SPATA13,ZNF304" MicroRNA hsa-miR-643:mirSVR_highEffct hsa-miR-643:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-22 7.45E-19 1.15E-21 1.05E-20 58 1056 "ATP6V1G3,COG6,KCTD12,CCNA1,CACNA1E,MPZL1,CAST,FCHO2,CHAMP1,FCGR2C,PDE4D,PGGT1B,ATAD2B,THAP6,TOGARAM2,HEATR5A,CLOCK,C12orf65,CEP135,DNM3,ZFYVE16,SREK1,CEP350,OCIAD1,GNPDA2,TSEN15,RB1,DTD2,POLR1D,MBNL2,EIF2B1,LGR6,ETF1,PCGF3,PCBD2,FNIP1,SUCO,FOXG1,THADA,CCDC88A,GABRA2,OXGR1,MIMT1,ANO4,DOCK9,TDG,ZBTB49,TMPO,MAEL,TXK,YTHDC2,FCRL6,IL6ST,ANKS1B,ZMYM2,FIP1L1,KIR2DL4,KIT" MicroRNA hsa-let-7g*:mirSVR_highEffct hsa-let-7g*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-22 7.60E-19 1.17E-21 1.07E-20 62 1207 "RALGAPA1,BIRC6,TBC1D14,CUL4A,SNX24,CENPBD1P1,ATP7B,FCRL3,BTF3,NFKBIA,CAD,CCNB1,UHMK1,PCSK1,PDGFRA,CENPC,ITGBL1,ATAD2B,THAP6,HOMER1,SREK1,COG3,CEP350,PTPRC,DNMT3A,FAM129A,B3GLCT,RB1,IPO4,SETDB2,MBNL2,TRAPPC13,LRRN2,RELL1,SDC1,HSD17B7,G2E3,NBEA,PLEKHA6,PAICS,IVNS1ABP,C1orf112,SLC22A4,GABRA2,MYT1L,GABRB1,GAK,ERBIN,PPARGC1A,TBC1D1,UGT2A1,UTP20,TMED2,ADGRL3,DOCK9,COX18,LINC01551,BAZ1A,TMPO,ZNF10,ZMYM2,MFSD2B" MicroRNA hsa-miR-1229:mirSVR_lowEffct hsa-miR-1229:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.50E-22 8.00E-19 1.23E-21 1.13E-20 70 1528 "MAP1B,IL17D,BIRC6,MCFD2,PPFIA4,APBB2,BLZF1,FAM193A,AACS,ZNF542P,B4GALT3,CADM3,CD84,NFATC4,NRL,CAST,CDK7,WDR66,RGSL1,PDE4D,CENPC,GLT1D1,PDE6B,CFAP54,FAM163A,VCAN,FAM169A,DNM3,SPATA18,OCIAD1,F11R,FAM129A,OGFOD2,PACRGL,RNASEL,KIRREL1,DHRS2,MAEA,ETF1,CLIP1,PCBD2,FCGR2B,TOMM40L,NDUFAF7,HSD17B7,STAB2,FBXO11,SCYL2,THADA,ZNF605,YPEL5,EFR3B,UGGT2,MEGF10,ZNF274,NFASC,MCCC2,ATP11A,RNF212,YIPF7,FCRLA,HAL,TMEM174,C12orf73,PLB1,KIF3C,KIT,RMST,TTC7A,AXDND1" MicroRNA hsa-miR-513a-5p:mirSVR_highEffct hsa-miR-513a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-22 8.01E-19 1.23E-21 1.13E-20 55 949 "ACOX3,ANKRD34B,CUL4A,ATP7B,ARHGEF7,CAST,FCGR2C,UHMK1,PCDH9,ZMYM5,CHD1,WDFY2,SLC25A3,NRXN1,ATAD2B,LTB4R,UGT2B28,POLN,HOMER1,ITSN2,FCRL5,COG3,TINF2,RAN,RNF31,ZNF329,RGS12,LATS2,KLHL12,MARVELD2,DNAJC27,ADGRV1,USP44,FCAR,SDC1,SUPT20H,SFSWAP,P2RX2,IQGAP2,ERAP1,NPAS3,KDM3B,MIMT1,PPARGC1A,DHRS4,ZNF544,ADGRL3,RNF17,ZBTB49,LINC01551,GTF3C2,NSD2,IL6ST,ZBED3-AS1,TTC41P" MicroRNA hsa-miR-708*:mirSVR_highEffct hsa-miR-708*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-22 8.02E-19 1.23E-21 1.13E-20 61 1170 "RALGAPA1,MAP1B,MATN3,LRRC43,NLN,ARL1,CAST,AMDHD1,CHAMP1,ZNF664,GPR180,STRN3,RCHY1,RNASE9,GNPTAB,UBXN2A,BIVM,SREK1,LOC439933,G3BP2,DHFR,RAN,TMEM161B,SMC6,POLR1D,PACRGL,SPATA9,ELF1,BORA,TBC1D19,CWC27,PCGF3,ELOVL7,TRAPPC13,SUCO,SDC1,G2E3,THADA,YPEL5,MEGF10,GABRB1,FAM114A1,NMNAT2,RAPGEF6,LRCH1,ERBIN,PPARGC1A,ADAM17,METAP2,EML4,KMT5A,TDG,FCRLA,HMGCR,STARD4,YTHDC2,MZF1,LHX9,ZBED3-AS1,LCP1,IFT88" MicroRNA hsa-miR-603:mirSVR_highEffct hsa-miR-603:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-22 8.52E-19 1.31E-21 1.20E-20 67 1407 "MAP1B,ADD1,EP400,ARHGAP5,AACS,NCOA1,ASTN1,CDKL2,FCHO2,CD1D,GLT1D1,CFL2,CCDC122,PGGT1B,TM9SF2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CSNK1G3,CEP135,FCRL2,MATR3,SREK1,COG3,CEP350,COCH,PTPRC,RNF219,SMC6,RGS4,CLIP4,POLR1D,GUSBP3,LATS2,FAM172A,CWC27,SH3YL1,PCBD2,NDUFAF7,PIBF1,SUCO,VEZT,NBEA,YPEL5,MEGF10,PDS5B,NAAA,CD244,MRPS27,NEDD1,ERBIN,PCDH17,PSME4,UGT2A1,TMPO,MAEL,ATP6V0A2,YTHDC2,ZNF84,ZMYM2,FIP1L1,KIR2DL4,KIT,IFT88,PABPN1" MicroRNA hsa-miR-1182:mirSVR_lowEffct hsa-miR-1182:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-22 8.72E-19 1.33E-21 1.22E-20 71 1572 "SFTA3,COG6,NYNRIN,APAF1,MSH2,DDX55,ZNF542P,BCL2L2,LINC02347,PNP,CACNA1E,CBLN3,LDB2,CD1D,PAH,RFLNA,PDE4D,MRPL57,POLN,PTPRVP,TAPT1,POLE,LYSMD3,C12orf65,FCRL5,NOS1AP,IFT172,OCIAD1,RGS12,POLR1D,DRAM1,MAEA,FGF9,HSD17B7,GOLGA2P5,STPG4,POTEM,CGREF1,SLC22A5,CHFR,DCAF11,MYT1L,KIF21B,PDS5B,NMNAT2,LRCH1,PSME4,PPIP5K2,METAP2,MTUS2,GOLGA3,CRB1,SLC7A8,ZBTB49,LINC01551,AP4S1,NPL,TPO,ADAMTS19,GPN1,ARHGAP30,SLAIN1,HTR2A,KCNT2,PLB1,ZBED3-AS1,KIF2A,KIR2DL4,LAD1,LINC00442,SKA3" MicroRNA hsa-miR-150*:mirSVR_highEffct hsa-miR-150*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-22 9.28E-19 1.42E-21 1.30E-20 55 952 "FAM193A,AACS,KCTD12,ARHGEF7,FCGR2C,PDE4D,JAKMIP1,STRN3,TAPT1,SNCAIP,FCRL2,SNX17,FBXL5,CEP350,C14orf119,TRAPPC12,LGR6,FAM81B,USP44,TOMM40L,N4BP2L2,POLK,VEZT,GOLGA2P5,FBXO11,G2E3,NBEA,NUBPL,IVNS1ABP,CCDC88A,C1orf112,SLC22A4,YPEL5,GABRA2,PDS5B,FAM114A1,TMEM183A,NPAS3,PCDH17,MAST4,PPIP5K2,ACSL6,DOCK9,TMPO,MAEL,ADAMTS19,SLAIN1,TENT2,KCNT2,ANKS1B,ZMYM2,TTC41P,NUAK2,AXDND1,IFT88" MicroRNA hsa-miR-559:PITA hsa-miR-559:PITA_TOP PITA 1.81E-22 9.65E-19 1.47E-21 1.35E-20 52 848 "ABL2,MCC,CUL4A,ASCL1,NCOA1,SLC4A4,BCL2L2,NOVA1,CDKL2,PCDH9,PDE4D,CFL2,NRXN1,BOD1L1,HECTD1,HOMER1,GNPTAB,CLOCK,ZFYVE16,MATR3,SREK1,CEP120,SACS,B3GLCT,TMEM161B,SMC6,MBNL2,ELF1,ELK3,DEPDC4,ETF1,PCGF3,CLIP1,FOXG1,ZCCHC8,G2E3,NBEA,IVNS1ABP,SLC8A1,CCDC88A,N4BP2,PDS5B,KDM3B,LPIN1,TMED2,ATP11A,SLC7A8,ATP6V0A2,SLAIN1,IGF1,ZBTB41,KIF2A" MicroRNA hsa-miR-588:mirSVR_lowEffct hsa-miR-588:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.95E-22 1.04E-18 1.58E-21 1.45E-20 74 1704 "RALGAPA1,BIRC6,TMEM132B,ACOX3,COG6,FAM193A,ZNF542P,CCNA1,ADGRD1,CDKL2,CCNB1,CDK18,GLT1D1,PFKFB2,PGGT1B,TM9SF2,BOD1L1,JAKMIP1,NCR1,HOMER1,CSNK1G3,MATR3,COG3,PARPBP,DNMT3A,TMEM161B,RGS12,RNASEL,TXNDC15,LGR6,DRAM1,ABCA11P,CLIP1,ELOVL7,SPON2,FGFR3,FOXG1,STAB2,RASA3,TMEM175,SLC34A2,BRMS1L,STPG4,ARHGEF40,CCDC88A,POTEM,WDCP,KIF21B,PDS5B,RAPGEF6,TMEM183A,NFASC,DRC1,RBKS,MCCC2,LRCH1,ANO4,RNF212,GRSF1,RIMBP2,ADAMTS19,HMGCR,HTR2A,IRF1,CHPT1,KCNJ9,KIR2DL4,DNAH10,LINC01913,NUAK2,AXDND1,IFT88,SPATA13,ZNF304" MicroRNA hsa-miR-219-1-3p:mirSVR_highEffct hsa-miR-219-1-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-22 1.05E-18 1.60E-21 1.46E-20 49 749 "IL17D,ATP12A,STARD13,ATP7B,LINC02347,PCCA,PCK2,FAM177A1,SCFD2,PDE4D,ITGBL1,LINC01085,TAPT1,RCHY1,VCAN,ITSN2,FCRL2,PIGG,TBC1D4,ARGLU1,MEMO1,POLR1D,GUSBP3,TXNDC15,RNF4,ABCA11P,GORAB,POLK,ZCCHC8,C1orf112,KIF21B,ERAP1,NFASC,KLHL20,MAST4,MTUS2,MAEL,ZNF721,PAPPA2,STARD4,YTHDC2,IGF1,CENPH,SDR39U1,TDRD3,ANKDD1B,DIAPH3,RMST,IFT88" MicroRNA hsa-miR-302d*:mirSVR_highEffct hsa-miR-302d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.04E-22 1.08E-18 1.64E-21 1.50E-20 65 1333 "SMIM15,MDM4,NLN,PITPNM2,APBB2,MSH2,CENPBD1P1,ATP1A2,CHAMP1,FCGR2C,PCDH9,PDE4D,PDGFRA,CFL2,WDFY2,LINC01085,HECTD1,PREPL,SNCAIP,LACC1,LRRTM2,CEP135,DNM3,UBXN2A,COG3,DMXL1,RNF219,SLC9C2,CLIP4,CRYL1,NTN4,LATS2,KLHL12,ABCA11P,N4BP2L2,FGFR3,SUCO,MROH9,SUPT20H,SGCG,NBEA,SLC30A6,N4BP2,GABRA2,MRPS27,CMPK2,DRC1,LRCH1,KLHL20,TMED2,EML4,TFDP1,LINC01551,ATP6V0A2,UBE2K,ARHGAP30,HMGCR,TECRL,GUF1,TENT2,STARD4,TADA2B,FAM151B,TTC41P,RMST" MicroRNA hsa-miR-516b:mirSVR_highEffct hsa-miR-516b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.11E-22 1.12E-18 1.70E-21 1.56E-20 58 1065 "BLZF1,STARD13,CD84,FCRL3,PCDH9,RGSL1,PDGFRA,VIT,PIGR,ADGRF3,AKAP6,PM20D1,FAM169A,FCRL2,BIVM,PSME1,SREK1,DMXL1,CEP350,NR1I3,NR1H4,EGLN3,FAM129A,RASA1,AASDH,DTD2,PACRGL,RNASEL,TMEM156,FGF9,RELL1,PIBF1,SUCO,FLT1,SUPT20H,NLRP2,PAICS,IVNS1ABP,CCDC88A,SLC12A2,JPH4,RAPGEF6,TMEM183A,GJB6,MCCC2,ADGRL3,RIPK3,C1QTNF9B,FCRLA,RNF17,AP4S1,TMPO,MAEL,ADAMTS19,ZNF324B,LINC00272,LINC01913,ZDHHC20" MicroRNA hsa-miR-630:mirSVR_highEffct hsa-miR-630:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-22 1.16E-18 1.75E-21 1.60E-20 62 1217 "SMIM15,RGS5,BLZF1,DAOA,PCDH9,CDK17,CFL2,CFAP54,ZFYVE16,IFT172,SREK1,COG3,DMXL1,CEP350,KLHL3,CEP120,PTPRC,PTPRH,DNMT3A,MEMO1,SETDB2,EIF2B1,LGR6,CWC27,SAP18,ABCA11P,SH3YL1,TMEM156,FNIP1,FGF9,RELL1,FOXG1,FLT1,SUPT20H,SF3B6,LIMCH1,KIF21B,NAAA,KDM3B,DRC1,NEDD1,LRCH1,LPIN1,ADGRL3,EML4,COX18,ACTR6,TMPO,ZNF721,ADAMTS19,UBE2K,HMGCR,TECRL,WDR36,YTHDC2,KCNT2,ZNF140,ZMYM2,ZBED3-AS1,CHPT1,KIF2A,TTC41P" MicroRNA hsa-miR-2117:mirSVR_highEffct hsa-miR-2117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-22 1.23E-18 1.86E-21 1.71E-20 60 1142 "MAP1B,SMIM15,MDM4,NYNRIN,AACS,ZNF542P,LINC02347,CD1D,CDK7,RGSL1,PDE4D,PDGFRA,VIT,CPNE6,JAKMIP1,LTB4R,LYSMD3,SNCAIP,LACC1,UBXN2A,PRKD1,PPP2R3C,DNMT3A,EIF2D,RNASEL,EIF2B1,UGT2A3,MAEA,ETF1,ABCA11P,GORAB,N4BP2L2,PIBF1,MROH9,VEZT,PAICS,GFM2,SLC8A1,SLC12A2,PUS1,GABRB1,IQGAP2,OXGR1,NFASC,RBKS,NPFFR2,PPARGC1A,STRN,FCRLA,LINC01551,GZMH,ZNF721,VRK2,ZNF26,JCHAIN,ZBTB41,FIP1L1,NUAK2,IFT88,LOX" MicroRNA hsa-miR-1304:mirSVR_lowEffct hsa-miR-1304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-22 1.24E-18 1.87E-21 1.71E-20 72 1624 "ACOX3,WDR35,EP400,UVSSA,ZNF784,ARL1,ASTN1,STARD13,FGFRL1,BCL2L2,LINC02347,MPZL1,RILPL1,PCDH9,CDK18,PDE4D,CCDC122,ZNF595,TSTD1,PTPRVP,THAP6,TAPT1,THTPA,SNCAIP,UBXN2A,CEP350,NUDT12,CEP120,F11R,SLC35F6,C12orf42,LINC01257,PARPBP,C14orf119,NR1H4,B3GLCT,RGS4,MEMO1,SETDB2,SNORA49,STX2,ABCA11P,GMPR2,TRAPPC13,FNIP1,TNFRSF19,SUPT20H,MBIP,GFM2,SLC12A2,PKD2L2,CGREF1,CIDEB,ZNF274,NPAS3,MIMT1,NPFFR2,ZBTB37,UTP20,EML4,CRB1,GTF2H3,ADAMTS19,GPN1,GUF1,VRK2,HTR2A,PLB1,CCDC190,FIP1L1,AXDND1,IFT88" MicroRNA hsa-miR-1243:mirSVR_highEffct hsa-miR-1243:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-22 1.29E-18 1.94E-21 1.78E-20 58 1068 "MAP1B,NDRG2,BIRC6,KIAA1211,SLAMF6,WDR35,MSH2,BLZF1,FCRL3,CD1E,PCDH9,SCFD2,ZNF595,PGGT1B,NRXN1,ATAD2B,BOD1L1,THAP6,RNASE9,GNPTAB,HEATR5A,SNCAIP,LACC1,ITSN2,COG3,G3BP2,TSEN15,RASA1,TXNDC15,LGR6,CWC27,FNIP1,PIBF1,SELP,VEZT,TM9SF1,FBXO11,UFM1,CCDC88A,WDCP,GABRA2,CMPK2,SRP72,MIMT1,PPARGC1A,PPIP5K2,TDG,CRB1,LINC01551,TMPO,ATP6V0A2,NPL,ADAMTS19,GUF1,RXFP2,KCNT2,IL6ST,CDK2AP1" MicroRNA hsa-miR-449b*:mirSVR_lowEffct hsa-miR-449b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-22 1.29E-18 1.95E-21 1.78E-20 76 1797 "RALGAPA1,ADD1,FBRSL1,ARHGAP5,BCL2L2,ARHGEF7,LINC02347,CCNB1,FCGR2C,CD1D,CDK18,PDE4D,PDE6B,PFKFB2,THAP6,C1orf116,POU2F1,HEATR5A,SNCAIP,CMTM5,SNX17,TBC1D4,RAN,OGFOD2,CRYL1,LATS2,TRAPPC12,KIRREL1,KLHL12,MARVELD2,STX2,SAP18,PCGF3,F10,FCAR,TOMM40L,POLK,THADA,SLC12A2,TMEM132D,NR5A2,CYP1B1-AS1,JPH4,ERAP1,NPAS3,DRC1,RBKS,MCCC2,LRCH1,LILRB1,ZBTB37,LPIN1,PPIP5K2,METAP2,C5orf56,TCF7,KMT5C,DOCK9,RNF212,C1QTNF9B,FCRLA,RNF17,CRB1,GPR161,ACTR6,UGT2B7,ZNF10,KCNT2,ZNF84,CCDC169,LHX9,ZBED3-AS1,RNASE11,LCP1,RMST,FAM71C" MicroRNA hsa-miR-1:mirSVR_highEffct hsa-miR-1:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.46E-22 1.31E-18 1.97E-21 1.80E-20 62 1220 "RALGAPA1,ANKRD34B,APC,DDX55,PNP,DAOA,CDKL2,TAF1B,PDGFRA,SMIM14,ZNF586,DCAF8,MATR3,EPS8L1,DMXL1,COCH,OCIAD1,GNPDA2,WDR1,NR1H4,RASA1,AASDH,DTD2,EIF2D,KLHL12,ZNF219,ADGRV1,NBEA,PAICS,UFM1,SLC8A1,NR5A2,CD244,OXGR1,NPAS3,LRCH1,PCDH17,PPARGC1A,ADGRA3,ANO4,TCF7,YIPF7,COX18,LINC01551,NPL,ADAMTS19,HSP90B1,HMGCR,ZNF550,NSD2,IGF1,MZF1,ZMYM2,SDR39U1,LHX9,TMEM178A,KIF2A,KIF3C,LINC01913,AXDND1,ZDHHC20,EEF1AKMT1" MicroRNA hsa-miR-365:mirSVR_lowEffct hsa-miR-365:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-22 1.37E-18 2.05E-21 1.88E-20 62 1221 "BIRC6,STXBP6,ATP1A2,ZNF542P,B4GALT3,MYH6,NFATC4,FCGR2C,CD1D,DCLK1,PDE4D,CHIT1,ZNF595,TM9SF2,ADGRF3,POLN,AKAP6,TOGARAM2,NGDN,ITSN2,FCRL5,GLT8D2,SNX17,BIVM,COG3,PTPRC,DHFR,NR1H4,ZNF329,TXNDC15,KIRREL1,ELK3,ADGRV1,POLK,SUCO,HSD17B7,TM9SF1,DDX51,SNRPF,KIF21B,PDS5B,RAPGEF6,NAAA,EAPP,LRCH1,ERBIN,MTUS2,ADGRL3,GTF2H3,TMPO,HPCAL1,ZNF10,ZNF470,ZMYM2,ZBTB41,LHX9,NPHS2,ZBED3-AS1,FIP1L1,DIAPH3,SPRYD7,IFT88" MicroRNA hsa-miR-28-5p:mirSVR_lowEffct hsa-miR-28-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-22 1.40E-18 2.10E-21 1.92E-20 73 1670 "MAP1B,NDRG2,BIRC6,EP400,FAM193A,CENPBD1P1,B4GALT3,MYH7,FCRL3,MPZL1,CDK17,CDK18,PDGFRA,PFKFB2,EPN1,GNPTAB,TOGARAM2,NGDN,GALNT9,VCAN,C12orf65,DNM3,CMTM5,FCRL5,NOS1AP,NR1I3,NR1H4,FAM228A,RGS4,PACRGL,TXNDC15,ELK3,MARVELD2,DHRS2,PCOTH,DLEU1,TLR6,ARL6IP4,SUCO,SDC1,FLT1,FTLP10,TM9SF1,ARHGEF40,ZNF605,P2RX2,MEGF10,OXGR1,KDM3B,DHRS4,ZNF544,METAP2,ADGRA3,LILRB4,RNF212,TDG,TEP1,ZBTB49,RAB2B,NPL,GPN1,STARD4,ZNF10,ZFHX2,ZNF470,GALP,LHX9,KIR2DL4,LINC01913,RMST,NUAK2,AXDND1,LMNB1" MicroRNA hsa-miR-10a:mirSVR_lowEffct hsa-miR-10a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-22 1.53E-18 2.29E-21 2.10E-20 70 1546 "TMEM132B,SEMA6A,BLZF1,SLC4A4,PNP,SNTG2,PDGFRA,CCDC122,PIGR,LINC01085,POLN,THAP6,TOGARAM2,CSNK1G3,CEP135,UBXN2A,EIF2AK2,ZNF586,IFT172,CEP350,SLC35F6,FAM129A,RNF31,ZNF329,PACRGL,MBNL2,KIRREL1,MARVELD2,TCTN2,BORA,DRAM1,SAP18,F7,PCBD2,FCAR,UTP15,GORAB,TNFRSF19,PIBF1,FLT1,SUPT20H,FBXO11,PAICS,STPG4,ZNF605,CGREF1,CYP1B1-AS1,MYT1L,RAPGEF6,MRPS27,MCCC2,ANKLE2,ERBIN,IKBIP,STRN,UTP20,ACSL6,RASSF6,RAB2B,TMPO,KLF12,HTR2A,YTHDC2,ZNF470,SPTSSA,ZBTB41,KCNN2,FIP1L1,MFSD2B,NUAK2" MicroRNA hsa-miR-629*:mirSVR_highEffct hsa-miR-629*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-22 1.55E-18 2.31E-21 2.12E-20 63 1263 "MDM4,DDX55,BLZF1,ARL1,ATP4B,KCTD12,CCNA1,PNP,PCSK1,RCBTB2,WDFY2,CFAP54,HOMER1,FAM53A,POU2F1,NGDN,SPATA18,PSME1,PTGS2,FBXL5,PTPRH,ATG10,DTD2,MBNL2,KLHL12,FCAMR,ETF1,ABCA11P,TOMM40L,SUCO,FOXG1,MROH9,FLT1,SLC34A2,TADA1,PKD2L2,SLC22A5,CHFR,PDS5B,RAPGEF6,TMEM183A,ERAP1,ATP8A2,SRP54,STRN,LINC02393,PPIP5K2,METAP2,C5orf56,ARHGEF28,NCSTN,RNF17,TEP1,GPR161,TMPO,ZNF721,NPL,HEXB,JCHAIN,ZMYM2,FIP1L1,RILPL2,PABPN1" MicroRNA hsa-miR-187*:mirSVR_lowEffct hsa-miR-187*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.94E-22 1.56E-18 2.33E-21 2.14E-20 67 1423 "IL17D,ADD1,COG6,HOMEZ,RGS5,ARL1,FAM193A,STXBP6,NCOA1,KCTD12,ARHGEF7,NOVA1,ZMYM5,PCSK1,PDE4D,CHD1,CPNE6,THAP6,HOMER1,POLE,DNM3,UBXN2A,DMXL1,LOC439933,CEP350,NUDT12,G3BP2,DNMT3A,FAM129A,ARGLU1,DTD2,NTN4,PACRGL,RNF4,ELF1,TCTN2,TBC1D19,ETF1,UTP15,NDUFAF7,TNFRSF19,PIBF1,FOXG1,FOXO1,FLT1,UFM1,CCDC88A,ZNF605,CGREF1,NR5A2,CHFR,NMNAT2,KDM3B,PPARGC1A,GJB2,ADAM17,PPIP5K2,MTUS2,RASSF6,GUF1,HPCAL1,KCNT2,ZNF140,SPTSSA,DIAPH3,KIT,IFT88" MicroRNA hsa-miR-496:mirSVR_highEffct hsa-miR-496:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.07E-22 1.63E-18 2.43E-21 2.23E-20 54 928 "MATN3,WDR35,MCFD2,NCOA1,NOVA1,TAF1B,CCNB1,PAH,PCDH9,CDK7,PCSK1,PDGFRA,NRXN1,LTB4R,AKAP6,TAPT1,GNPTAB,CRHBP,PRKD1,DMXL1,LOC439933,CEP120,RABGAP1L,FAM129A,RASA1,UGT2A3,DRAM1,MAEA,TMEM156,GORAB,N4BP2L2,RELL1,PIBF1,SUCO,FLT1,SLC34A2,G2E3,SLC12A2,NR5A2,LIMCH1,MYT1L,NAAA,RBKS,ADGRA3,EML4,DOCK9,AP4S1,RASSF6,HMGCR,GUF1,HSD17B4,ZNF140,FAM151B,RMST" MicroRNA hsa-miR-149:mirSVR_highEffct hsa-miR-149:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.11E-22 1.65E-18 2.45E-21 2.25E-20 49 757 "ADD1,SLC4A4,CD1E,RFLNA,CDK17,PDGFRA,PGGT1B,LTB4R,PTPRVP,THAP6,TOGARAM2,POU2F1,SNCAIP,KLHL3,RABGAP1L,RAN,EGLN3,RNF31,GUSBP3,TXNDC15,DLEU1,ELOVL7,FCGR3A,FCGR3B,FLT1,FMO1,RUBCNL,ARHGEF40,ZNF667,GABRA2,DRC1,PSME4,TCF7,COP1,SLC7A8,GPN1,HSD17B4,JCHAIN,C12orf73,LHX9,TDRD3,ZBED3-AS1,KIF2A,RNASE11,TTC41P,AXDND1,LMNB1,PABPN1,LOX" MicroRNA hsa-miR-4268:mirSVR_lowEffct hsa-miR-4268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-22 1.67E-18 2.47E-21 2.26E-20 74 1718 "ADD1,ADORA1,WDR35,CUL4A,EP400,RGS5,SLC4A4,CADM3,ATP7B,BCL2L2,NFATC4,DAOA,MPZL1,CAST,UHMK1,PAH,TM9SF2,POLN,PTPRVP,C1orf116,THTPA,EPGN,NGDN,ITSN2,FCRL2,SPATA18,EPS8L1,COG3,NUDT12,LINC01257,FAM129A,RB1,TXNDC15,SAP18,MAEA,PCGF3,ARL6IP4,FCAR,SPON2,SUCO,FLT1,FLT3,SGCG,BRMS1L,ALKAL2,NUBPL,CCDC88A,SLC12A2,CGREF1,C1orf112,MYT1L,KDM5B,RAPGEF6,MCCC2,DHRS4,INSM2,MTUS2,ARHGEF28,STON1,TDG,TEP1,SLC7A8,RIMBP2,UBE2K,NSD2,ZNF324B,PLB1,LHX9,FIP1L1,LINC01913,LETM1,AXDND1,LMNB1,PABPN1" MicroRNA hsa-miR-589:mirSVR_lowEffct hsa-miR-589:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-22 1.71E-18 2.53E-21 2.31E-20 70 1549 "MAP1B,SEMA6A,CUL4A,RGS5,NOP14,CENPBD1P1,CCDC181,ATP2B4,BTF3,AP1G2,NOVA1,CACNA1E,CDKL2,RILPL1,PDGFRA,PFKFB2,TM9SF2,THAP6,AKAP6,COPA,PM20D1,THTPA,CMTM5,EIF2AK2,MATR3,PIGG,COG3,DHFR,PXMP2,EGLN3,RB1,SMC6,RGS12,LATS2,EFS,ARSK,ADGRV1,PCBD2,LRRN2,SDC1,FOXO1,ZNF605,GABRA2,GABRB1,PDS5B,ZNF274,NFASC,LRCH1,KLHL20,NMU,CFHR4,MTUS2,RNF17,ZBTB49,MAEL,TPO,TUBA3C,GUF1,SLAIN1,ZNF876P,NSD2,DCP2,FCRL6,ZNF324B,FAM151B,KCNN2,RILPL2,LAD1,LINC01913,SPRYD7" MicroRNA hsa-miR-1288:mirSVR_lowEffct hsa-miR-1288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.32E-22 1.77E-18 2.61E-21 2.39E-20 58 1075 "MATN3,ADORA1,NLN,CUL4A,RGS5,DHX37,MSH2,ARL1,FAM193A,STXBP6,AACS,ASTN1,ZNF542P,BCL2L2,NFATC4,FCRLB,PCDH9,ZMYM5,PDGFRA,CENPC,SMIM14,HEATR5A,EPS8L1,FBXL5,GNPDA2,NR1H4,DNMT3A,RAN,ATG10,RNF31,AASDH,MPHOSPH9,STK32B,F10,SUCO,FLT1,TM9SF1,NBEA,POTEM,P2RX2,SLC22A4,MYO16,UHRF1BP1L,PSME4,TBC1D1,ADGRL3,TCF7,ZBTB49,ADAMTS19,VRK2,WDR36,IGF1,CENPH,IL6ST,PLB1,LHX9,KCNJ9,LAD1" MicroRNA hsa-miR-1226:mirSVR_lowEffct hsa-miR-1226:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-22 1.79E-18 2.64E-21 2.42E-20 78 1895 "RALGAPA1,MDM4,NDRG2,ADD1,KIAA1211,ULK1,EP400,BLZF1,AACS,CD84,NFATC4,ARHGEF7,CACNA1E,CBLN3,WDR66,CEBPE,ADGRF3,PTPRVP,COPA,FAM53A,TOGARAM2,PM20D1,SNCAIP,FCRL5,NOS1AP,ZFYVE16,PIGG,DMXL1,LINC01257,DNMT3A,RB1,ARGLU1,RGS12,RNASEL,ELF1,FCAMR,BORA,STX2,DLEU1,DNAJC27,ARL6IP4,IRF9,TMEM129,TOMM40L,N4BP2L2,DDX51,MBIP,C1orf112,DCAF11,MEGF10,ALLC,TMEM183A,ZNF274,DRC1,ERBIN,PPARGC1A,PPIP5K2,FCRLA,TFDP1,CRB1,SLC7A8,ZBTB49,GZMH,MAEL,TPO,TECRL,WDR36,IL25,ZNF470,KCNN2,KIR2DL4,KIR2DS4,LAD1,LCP1,LETM1,TTC7A,AXDND1,LMNB1" MicroRNA hsa-miR-502-3p:mirSVR_lowEffct hsa-miR-502-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-22 1.79E-18 2.64E-21 2.42E-20 64 1306 "RGS5,AACS,ATP1A2,ZNF542P,LINC02347,CAMK4,RILPL1,DCLK1,PCK2,CDK17,PDE4D,PFKFB2,TM9SF2,SMIM14,TAPT1,GNPTAB,TOGARAM2,LYSMD3,FAM169A,KIAA0040,NOS1AP,PTGS2,KLHL3,NUDT12,F11R,TINF2,GNPDA2,SLC35F6,DNMT3A,FAM129A,SLC9C2,GUSBP3,GP6,ETF1,ADGRV1,PCGF3,TOMM40L,RELL1,SUPT20H,UFM1,EFR3B,MYT1L,JPH4,ATP8A2,NFASC,NEDD1,PPARGC1A,GJA3,PPIP5K2,ANO4,GPR12,KMT5C,DOCK9,XPO4,FCRLA,ACTR6,NPL,KLF12,TENT2,PLB1,TMEM178A,KIF2A,IFT88,LOX" MicroRNA hsa-miR-103-as:mirSVR_lowEffct hsa-miR-103-as:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.38E-22 1.80E-18 2.65E-21 2.43E-20 61 1189 "NDRG2,ADD1,NLN,SNX24,APC,ARL1,AACS,NCOA1,CDKL2,MPZL1,CDK17,GLT1D1,CFL2,PFKFB2,ZNF595,WDFY2,ATAD2B,PTPRVP,CLOCK,KIAA0040,FCRL2,ZFYVE16,SREK1,GNPDA2,C14orf119,RB1,ARGLU1,SETDB2,LRPPRC,GRTP1,ELF1,STX2,ARSK,F7,PIBF1,SDC1,NUBPL,TADA1,CCDC88A,GABRA2,CENPJ,MRPS27,NFASC,NEDD1,LILRB1,KLHL20,ZBTB37,ZNF544,XPO4,FCRLA,RNF17,TGFBI,AP4S1,RASSF6,TMPO,NPL,GPN1,TECRL,GUF1,LHX9,RILPL2" MicroRNA hsa-miR-100*:mirSVR_highEffct hsa-miR-100*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.61E-22 1.92E-18 2.82E-21 2.58E-20 53 896 "RALGAPA1,BIRC6,CENPBD1P1,STARD13,CCNA1,CAST,RILPL1,CD1D,PAH,PCDH9,FAM177A1,PCSK1,CDK17,CHD1,CCDC122,BOD1L1,HECTD1,THAP6,TOGARAM2,CEP135,FAM169A,PSMA6,SREK1,DMXL1,OCIAD1,TSEN15,RNF219,B3GLCT,PACRGL,PCGF3,NDUFAF7,FGF9,SUCO,FBXO11,NBEA,UFM1,IVNS1ABP,GABRA2,MYT1L,FAM114A1,OXGR1,RBKS,PPARGC1A,MAST4,ADAM17,TCF7,NT5C1B,TXK,ZNF876P,LHX9,DIAPH3,CDK2AP1,IFT88" MicroRNA hsa-miR-3129:mirSVR_lowEffct hsa-miR-3129:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.65E-22 1.94E-18 2.85E-21 2.61E-20 69 1511 "MAP1B,BIRC6,TBC1D14,WDR35,SEMA6A,SNX24,MCFD2,APBB2,CAMK4,MPZL1,ZMYM5,RGSL1,ZNF595,STRN3,TAPT1,RCHY1,POU2F1,ITSN2,DNM3,BIVM,PIGG,COG3,CEP350,KLHL3,NUDT12,B3GLCT,AASDH,SLC9C2,PACRGL,LATS2,FCAMR,ABCA11P,PCBD2,TNFRSF19,PIBF1,POLK,FLT1,FTLP10,FBXO11,CCDC92,CCDC88A,SLC12A2,SLC22A5,PDS5B,NAAA,TMEM183A,IQGAP2,ERAP1,HSPH1,NFASC,RBKS,MCCC2,PCDH17,MIMT1,GJA3,TBC1D1,METAP2,ADGRL3,DOCK9,ZBTB49,RIMBP2,WDR36,ZNF470,PLB1,SPTSSA,DNAH10,RMST,SPRYD7,AXDND1" MicroRNA hsa-miR-1233:mirSVR_lowEffct hsa-miR-1233:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.77E-22 2.01E-18 2.94E-21 2.69E-20 66 1389 "ADD1,ATP6V1G3,APAF1,WDR19,CENPBD1P1,PNP,NRL,CAST,PCDH9,CDK18,PDGFRA,TSTD1,HECTD1,RCHY1,SNCAIP,VCAN,DMXL1,LOC439933,TINF2,SACS,DHFR,DNMT3A,GALNT14,ATG10,TMEM161B,TMEM33,MEMO1,SETDB2,PACRGL,RNASEL,RNF4,KLHL12,DHRS2,ARSK,ABCA11P,GMPR2,SLC22A17,TMEM129,UTP15,TM9SF1,NUBPL,PAICS,TADA1,ZNF667,KIF21B,PDS5B,KDM3B,NFASC,LILRB1,ZBTB37,UTP20,NT5C1B,TFDP1,TGFBI,LINC01551,AP4S1,ZNF721,TNR,HMGCR,VRK2,NSD2,ANKS1B,PGAM5,ZBED3-AS1,SKA3,ZNF304" MicroRNA hsa-miR-329:mirSVR_lowEffct hsa-miR-329:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.83E-22 2.04E-18 2.98E-21 2.73E-20 74 1724 "ADD1,KIAA1211,NYNRIN,SEMA6A,PPFIA4,UVSSA,AACS,NCOA1,CADM3,SLC5A6,PNP,CDKL2,CAMK4,LDB2,WDR66,LINC01085,ATAD2B,BOD1L1,HECTD1,DNM3,NOS1AP,IFT172,MATR3,PTPRC,SACS,G3BP2,GNPDA2,PARPBP,RNF219,FAM129A,ATG10,EFNA5,LATS2,DHRS2,CWC27,SAP18,ETF1,ELOVL7,FNIP1,VEZT,ZNF605,POTEM,TMEM132D,CGREF1,SLC22A4,YPEL5,KIF21B,PDS5B,NAAA,ATP8A2,NPAS3,KDM3B,ANKLE2,IKBIP,BRD8,PSME4,PPIP5K2,GOLGA3,ADGRL3,ADGRA3,ANO4,KHNYN,CRB1,AP4S1,ZNF876P,TENT2,YTHDC2,ZNF84,ZMYM2,CAB39L,KIF2A,TTC7A,LMNB1,IFT88" MicroRNA hsa-miR-20b*:mirSVR_highEffct hsa-miR-20b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.96E-22 2.11E-18 3.08E-21 2.82E-20 52 863 "MAP1B,MDM4,ATP6V1G3,APC,ARL1,ARHGEF7,NRL,CAST,LDB2,CD1D,CD1E,ZMYM5,FAM177A1,RGSL1,PDE4D,ZNF595,BOD1L1,HECTD1,EPGN,FCRL5,COG3,TBC1D4,SUPT7L,DRAM1,ABCA11P,FLT3,CHFR,PDS5B,NPAS3,KLHL20,PCDH17,COMMD6,STRN,PSME4,LINC02393,ANO4,RNF17,CRB1,TGFBI,ACTR6,TMPO,MAEL,ZNF721,HMGCR,GUF1,ZNF876P,STARD4,ZNF470,ZMYM2,LHX9,KCNN2,DIAPH3" MicroRNA hsa-miR-129*:mirSVR_highEffct hsa-miR-129*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.10E-22 2.18E-18 3.18E-21 2.91E-20 42 543 "IL17D,NDRG2,BIRC6,NLN,SLC5A6,CDKL2,PCCA,CFAP54,HECTD1,GNPTAB,POU2F1,FCRL5,COG3,DMXL1,SACS,SUPT7L,EGLN3,FAM129A,RB1,TMEM161B,RGS12,MEMO1,PACRGL,BORA,FCAR,POLK,VEZT,JPH4,HSPH1,KDM3B,ERBIN,KLHL20,ZBTB37,TCF7,CRB1,GTF2H3,FZD10,TNR,STARD4,YTHDC2,CHPT1,TTC41P" MicroRNA hsa-miR-19b-3p:TargetScan hsa-miR-19b-3p TargetScan 4.16E-22 2.21E-18 3.22E-21 2.95E-20 55 970 "MAP1B,MCC,MDM4,KIAA1211,PITPNM2,ARHGAP5,ATP1A2,CD84,CAST,CFL2,NUP37,PITX1,HOMER1,POU2F1,EPGN,CLOCK,NGDN,LRRTM2,DCAF8,CEP350,KLHL3,G3BP2,DNMT3A,RASA1,REST,CLIP4,MEMO1,EFNA5,MBNL2,ELK3,CLIP1,PCBD2,SDC1,G2E3,NBEA,IVNS1ABP,CCDC88A,LIMCH1,MYT1L,FAM114A1,NPAS3,LRCH1,KLHL20,NPFFR2,ATP11A,GRSF1,RAB2B,KLF12,DCP2,IGF1,IL6ST,LHX9,LMLN,CAB39L,KIT" MicroRNA hsa-miR-19a-3p:TargetScan hsa-miR-19a-3p TargetScan 4.16E-22 2.21E-18 3.22E-21 2.95E-20 55 970 "MAP1B,MCC,MDM4,KIAA1211,PITPNM2,ARHGAP5,ATP1A2,CD84,CAST,CFL2,NUP37,PITX1,HOMER1,POU2F1,EPGN,CLOCK,NGDN,LRRTM2,DCAF8,CEP350,KLHL3,G3BP2,DNMT3A,RASA1,REST,CLIP4,MEMO1,EFNA5,MBNL2,ELK3,CLIP1,PCBD2,SDC1,G2E3,NBEA,IVNS1ABP,CCDC88A,LIMCH1,MYT1L,FAM114A1,NPAS3,LRCH1,KLHL20,NPFFR2,ATP11A,GRSF1,RAB2B,KLF12,DCP2,IGF1,IL6ST,LHX9,LMLN,CAB39L,KIT" MicroRNA hsa-miR-4298:mirSVR_lowEffct hsa-miR-4298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.24E-22 2.25E-18 3.28E-21 3.00E-20 73 1684 "MCC,MDM4,NDRG2,TMEM132B,SLAMF6,EP400,PPFIA4,UVSSA,AACS,SLC4A4,ATP2B4,AP1G2,CACNA1E,CBLN3,RILPL1,CDK18,CKMT2,PTPRVP,AKAP6,SNCAIP,UBXN2A,DCAF8,SREK1,CEP350,NUDT12,PTPRC,RABGAP1L,GNPDA2,SUPT7L,PARPBP,EGLN3,DTD2,RNF4,LGR6,ZNF219,DRAM1,PCBD2,FCGR2B,N4BP2L2,SELP,UFM1,TMEM132D,SLC15A4,CGREF1,GABRA2,CENPJ,NPAS3,RBKS,MCCC2,LRCH1,PPARGC1A,MAST4,TBC1D1,ADGRA3,C5orf56,KHNYN,NCSTN,RNF17,TFDP1,CRB1,UBE2K,TXK,NLRP8,ZNF470,CCDC169,PLB1,ZMYM2,PGAM5,ZBED3-AS1,FIP1L1,RILPL2,IFT88,ZNF304" MicroRNA hsa-miR-668:mirSVR_lowEffct hsa-miR-668:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.26E-22 2.27E-18 3.29E-21 3.01E-20 64 1312 "MDM4,FBRSL1,ARL1,ZNF542P,NFKBIA,PNP,FCGR2C,PCCA,PCSK1,CCDC122,ITGBL1,NRXN1,LINC01085,SMIM14,PTPRVP,THAP6,HOMER1,HEATR5A,EPGN,NGDN,ZFYVE16,CEP120,OCIAD1,PTPRH,G3BP2,GNPDA2,PARPBP,C14orf119,TMEM161B,POLR1D,ELF1,KLHL12,FAM172A,F10,FGF9,SDC1,FOXG1,NBEA,SLC30A6,IVNS1ABP,ARHGEF40,YPEL5,UGGT2,GABRA2,HSPH1,MIMT1,GJA3,STRN,PPIP5K2,ANO4,YIPF7,TXK,NSD2,DCP2,ZNF470,ZMYM2,KCNN2,FIP1L1,DIAPH3,RNASE11,DNAH10,LINC01913,RMST,ZDHHC20" MicroRNA hsa-miR-558:mirSVR_lowEffct hsa-miR-558:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.56E-22 2.43E-18 3.52E-21 3.22E-20 71 1601 "LRRC43,ANKRD34B,PITPNM2,RGS5,UVSSA,ZNF784,ARL1,AACS,CCDC181,ZNF542P,NFATC4,CCNA1,NRL,ZNF664,PCDH9,WDFY2,SNX6,PTPRVP,AKAP6,STRN3,GNPTAB,SYCP3,LYSMD3,CLOCK,PREPL,BRI3BP,GALNT9,FAM169A,MPHOSPH8,DCAF8,COG3,RNF31,AASDH,LRPPRC,PACRGL,EFNA5,MPHOSPH9,FAM172A,ABCA11P,FCGR3A,TNFRSF19,STAB2,TM9SF1,PLEKHA6,SLC8A1,C1orf112,NR5A2,PUS1,GABRB1,NMNAT2,RAPGEF6,RBKS,MAST4,LILRB4,DOCK9,COP1,NCSTN,FCRLA,TGFBI,RAB2B,RIMBP2,NPL,ADAMTS19,VRK2,PLB1,KIR2DL4,KIR2DS4,LINC01913,RMST,LMNB1,LTA4H" MicroRNA hsa-miR-376c:mirSVR_highEffct hsa-miR-376c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.97E-22 2.64E-18 3.82E-21 3.50E-20 67 1437 "RALGAPA1,MAP1B,KIAA1211,TBC1D14,UVSSA,ARL1,NCOA1,ATP4B,KCTD12,CACNA1E,FCHO2,NFXL1,PDGFRA,RCBTB2,PFKFB2,ZNF595,GPR180,BOD1L1,RCHY1,EPGN,CLOCK,CEP135,DNM3,MPHOSPH8,SPATA18,DCT,LOC439933,NUDT12,PTPRC,OCIAD1,SACS,RABGAP1L,GNPDA2,PPP2R3C,RNF219,NTN4,UTP15,FLT3,VEZT,SLC8A1,LIMCH1,MEGF10,GABRA2,GABRB1,KIF21B,KDM5B,NAAA,ZNF274,OXGR1,ERBIN,ZNF544,UGT2A1,INSM2,ADGRL3,C1QTNF9B,TEP1,BAZ1A,RIMBP2,ATP6V0A2,TXK,CCDC169,ZMYM2,FAM49A,DIAPH3,AMTN,TTC41P,RMST" MicroRNA hsa-miR-331-5p:mirSVR_highEffct hsa-miR-331-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.26E-22 2.80E-18 4.04E-21 3.70E-20 51 834 "RALGAPA1,IL17D,COG6,SNX24,ARHGAP5,STARD13,CAMK4,ZNF664,ZMYM5,FAM177A1,CDK18,CFAP54,PKP1,GNPTAB,CSNK1G3,CEP135,DCAF8,COG3,NUDT12,RABGAP1L,GNPDA2,SUPT7L,PARPBP,RNASEL,ELF1,CWC27,SAP18,DNAJC27,TRAPPC13,PCBD2,GORAB,FNIP1,FOXG1,RUBCNL,G2E3,BRMS1L,IVNS1ABP,MYT1L,PDS5B,SRP54,BRD8,METAP2,EML4,TDG,CRB1,GTF2H3,BAZ1A,WDR36,PLB1,CHPT1,DNAH10" MicroRNA hsa-miR-1283:PITA hsa-miR-1283:PITA_TOP PITA 5.43E-22 2.89E-18 4.17E-21 3.81E-20 45 638 "RALGAPA1,ADD1,NYNRIN,SLC4A4,ODC1,FCHO2,PDE4D,CHD1,ATAD2B,LYSMD3,CRHBP,MATR3,BIVM,CEP350,COCH,G3BP2,MBNL2,ELF1,TCTN2,MAEA,ETF1,PCGF3,NBEA,BRMS1L,CCDC88A,N4BP2,NR5A2,MYO16,MEGF10,MYT1L,KDM3B,PPARGC1A,PPIP5K2,CNTN2,STON1,KMT5A,ZBTB49,KLF12,TRPC4,HMGCR,SLAIN1,TENT2,DCP2,IGF1,ZMYM2" MicroRNA hsa-miR-223:mirSVR_lowEffct hsa-miR-223:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.82E-22 3.09E-18 4.46E-21 4.08E-20 71 1608 "MATN3,BIRC6,NLN,COG6,WDR35,SNX24,NCOA1,ASTN1,ATP12A,CD84,PCCA,PCDH9,PCK2,PDE4D,PDGFRA,CHD1,VIT,JAKMIP1,THAP6,POU2F1,SNCAIP,CSNK1G3,FCRL5,ZFYVE16,DGKQ,COG3,CEP350,KLHL3,PACRGL,LATS2,RNF4,EIF2B1,ELK3,DLEU1,DNAJC27,SH3YL1,UTP15,TOMM40L,TNFRSF19,FLT1,SUPT20H,NBEA,THADA,SLC15A4,TNFSF13B,UGGT2,MYO16,NMNAT2,RAPGEF6,UHRF1BP1L,IKBIP,NMU,ATP11A,ADGRL3,LILRB4,TCF7,RIPK3,STON1,EML4,CRB1,MSH6,RAB2B,ADAMTS19,TENT2,PAPPA2,KCNT2,ZFHX2,PGAM5,LHX9,ZDHHC20,IFT88" MicroRNA hsa-miR-188-5p:mirSVR_lowEffct hsa-miR-188-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.98E-22 3.18E-18 4.58E-21 4.19E-20 67 1442 "TBC1D14,SEMA6A,DDX55,ARL1,SLC4A4,BCL2L2,LINC02347,NOVA1,XPR1,CDK18,PDGFRA,CFL2,PFKFB2,CCDC122,MRPL57,ITGBL1,CFAP54,LTB4R,AKAP6,POU2F1,CSNK1G3,VCAN,FCRL5,LOC439933,FAM228A,POLR1D,ARSK,STK32B,ETF1,ADGRV1,TMEM156,NDUFAF7,N4BP2L2,PIBF1,POLK,MROH9,STAB2,FBXO11,BRMS1L,MBIP,SLC12A2,UGGT2,CYP1B1-AS1,GABRA2,KDM5B,HSPH1,SRP54,NFASC,ANKLE2,ERBIN,LILRB1,ZBTB37,GJA3,STON1,DOCK9,BAZ1A,HEXB,ADAMTS19,GUF1,NSD2,ZNF470,ZNF140,SPTSSA,LHX9,RILPL2,TTC41P,AXDND1" MicroRNA hsa-miR-670:mirSVR_highEffct hsa-miR-670:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.09E-22 3.24E-18 4.65E-21 4.26E-20 55 978 "MDM4,ADD1,HOMEZ,APC,STARD13,CD84,ARHGEF7,CACNA1E,FCHO2,CDK17,RGSL1,GLT1D1,ZNF595,WDFY2,GPR180,HOMER1,LACC1,CEP135,FCRL5,ZNF586,ZFYVE16,BIVM,COG3,PTGS2,DMXL1,TINF2,FAM129A,B3GLCT,DTD2,PACRGL,ABCA11P,PIBF1,ZCCHC8,SLC22A4,CYP1B1-AS1,ZBTB37,PPIP5K2,METAP2,C5orf56,GPR12,TDG,ZBTB49,BAZ1A,ZNF721,NPL,GPN1,GUF1,TENT2,STARD4,CCDC169,GALP,ZBED3-AS1,KCNJ9,KCNN2,IFT88" MicroRNA hsa-miR-557:mirSVR_highEffct hsa-miR-557:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.01E-22 3.73E-18 5.35E-21 4.90E-20 55 981 "MATN3,ULK1,CUL4A,SNX24,NCOA1,FCRL3,CAMK4,PCCA,PCDH9,CDK7,PGGT1B,SLC25A3,NRXN1,NUP37,THAP6,HOMER1,AKAP6,FCRL5,FCRL2,GLT8D2,SPATA18,SREK1,COG3,G3BP2,RB1,ZNF329,POLR1D,SETDB2,KLHL12,MARVELD2,GP6,DEPDC4,STK32B,TNFRSF19,FOXO1,FLT1,SCYL2,GABRA2,NAAA,LRCH1,PCDH17,DHRS4,ADAM17,PPIP5K2,MTUS2,ANO4,LINC01551,HAL,TXK,GUF1,VRK2,KCNJ9,AXDND1,LOX,SPATA13" MicroRNA hsa-miR-142-3p:mirSVR_lowEffct hsa-miR-142-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.12E-22 3.79E-18 5.43E-21 4.97E-20 59 1130 "MDM4,ANKRD34B,COG6,SNX24,MCFD2,ZNF784,ARL1,CD84,LINC02347,ADGRD1,NOVA1,NRL,PCK2,RGSL1,GLT1D1,PDE6B,DHRS1,TM9SF2,EPN1,COPA,RCHY1,FAM169A,EPS8L1,RASA1,RB1,RGS12,NTN4,TRAPPC12,STX2,EFS,GORAB,N4BP2L2,FGFR3,FLT1,FTLP10,FBXO11,CCDC92,STPG4,TADA1,ZNF605,PDS5B,KDM5B,OXGR1,NPAS3,MIMT1,UTP20,TCF7,DOCK9,TGM1,LINC01551,RIMBP2,MAEL,ADAMTS19,IGF1,ZNF84,ANKS1B,ZMYM2,LINC00272,LHX9" MicroRNA hsa-miR-599:mirSVR_highEffct hsa-miR-599:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.62E-22 4.05E-18 5.79E-21 5.31E-20 53 911 "BIRC6,MCFD2,AACS,ATP2B4,FCHO2,PDE4D,PGGT1B,BOD1L1,LTB4R,AKAP6,FAM163A,CLOCK,LACC1,C12orf65,CEP135,CMTM5,PRKD1,FCRL5,ZNF586,COG3,PTPRC,RABGAP1L,NR1H4,DNMT3A,ATG10,LAP3,CLIP4,MEMO1,POLR1D,TOMM40L,PIBF1,FOXO1,SGCG,YPEL5,KDM5B,NAAA,TMEM183A,ERAP1,STRN,BRD8,UGT2A1,ANO4,C1QTNF9B,ARHGAP30,SLAIN1,TENT2,IGF1,ANKS1B,FIP1L1,TTC41P,SLAMF9,AXDND1,SPATA13" MicroRNA hsa-miR-548s:mirSVR_highEffct hsa-miR-548s:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.13E-22 4.32E-18 6.17E-21 5.65E-20 54 948 "BIRC6,SLAMF6,ARHGEF7,CCNA1,ADGRD1,RGSL1,PDE4D,PDGFRA,WDFY2,ITGBL1,HOMER1,COPA,CSNK1G3,VCAN,FAM169A,UBXN2A,DCAF8,MATR3,SREK1,DMXL1,CEP350,CEP120,TSEN15,NR1H4,RB1,TMEM161B,MPHOSPH9,ARSK,SAP18,CLIP1,GORAB,TNFRSF19,SUCO,FOXG1,HSD17B7,VEZT,NUBPL,GABRB1,OXGR1,MCCC2,ERBIN,ZBTB37,GJA3,ATP11A,TCF7,COP1,TEP1,ACTR6,RIMBP2,ARHGAP30,SLAIN1,YTHDC2,KCNN2,TTC41P" MicroRNA hsa-miR-876-5p:mirSVR_highEffct hsa-miR-876-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.35E-22 4.44E-18 6.33E-21 5.80E-20 60 1172 "TMEM132B,SLAMF6,ATP6V1G3,SEMA6A,SNX24,AACS,CENPBD1P1,TAF1B,PAH,WDFY2,ITGBL1,COPA,SNCAIP,COG3,TBC1D4,F11R,TINF2,GNPDA2,B3GLCT,SMC6,CLIP4,ZNF419,SETDB2,TXNDC15,CWC27,MAEA,ABCA11P,TOMM40L,SULT6B1,PIBF1,VEZT,NUBPL,SLC30A6,IVNS1ABP,THADA,TADA1,SLC15A4,YPEL5,CYP1B1-AS1,GABRA2,CD244,MRPS27,FCRLA,LINC01551,RASSF6,RIMBP2,ZNF721,HAL,HEXB,ADAMTS19,TXK,ZNF876P,STARD4,DCP2,ZNF26,SPTSSA,ZMYM2,LHX9,AMTN,LOX" MicroRNA hsa-miR-877*:mirSVR_highEffct hsa-miR-877*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.41E-22 4.48E-18 6.37E-21 5.84E-20 58 1096 "ATP2B4,STARD13,ARHGEF7,BTF3,NOVA1,CACNA1E,CAST,PCDH9,RGSL1,PDGFRA,VIT,LTB4R,THAP6,UBXN2A,ZNF586,GALNT14,GUSBP3,PACRGL,RNASEL,ELK3,FCAMR,TBC1D19,DRAM1,ARL6IP4,IRF9,TOMM40L,FGFR3,PIBF1,POLK,SUCO,FOXO1,VEZT,SCYL2,ZNF605,C1orf112,SLC22A5,MYT1L,DRC1,MCCC2,BRD8,ZNF544,PPIP5K2,ADGRL3,RNF17,ADAMTS19,TXK,GUF1,ZNF10,FAM151B,FAM49A,KCNN2,FIP1L1,TTC41P,NUAK2,AXDND1,LIG4,LMNB1,PABPN1" MicroRNA hsa-miR-106a*:mirSVR_highEffct hsa-miR-106a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.59E-22 4.57E-18 6.50E-21 5.95E-20 57 1059 "RALGAPA1,SFTA3,CDKL4,AACS,NCOA1,ASTN1,ATP1A2,SLC4A4,ZNF542P,CAST,LDB2,SCFD2,CDK17,RGSL1,ZNF595,AKAP6,GNPTAB,LACC1,KIAA0040,SREK1,PTGS2,DMXL1,GNPDA2,RGS12,PACRGL,SNORA53,CWC27,ETF1,CLIP1,FCGR3A,TOMM40L,FCGR3B,NDUFAF7,PIBF1,PEAR1,SCYL2,CCDC88A,PUS1,LIMCH1,GJB6,HSPH1,SRP54,SULT1E1,PPARGC1A,PPIP5K2,ADGRL3,YIPF7,HAL,TECRL,GUF1,SLAIN1,ZNF84,SPTSSA,ZMYM2,FAM151B,RMST,CDK2AP1" MicroRNA hsa-miR-132:mirSVR_highEffct hsa-miR-132:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.61E-22 4.58E-18 6.51E-21 5.96E-20 56 1022 "KIAA1211,SEMA6A,SNX24,APAF1,CDKL4,MSH2,NOVA1,UHMK1,CFL2,CHD1,VIT,LTB4R,CSNK1G3,FCRL5,SREK1,PTGS2,PARPBP,RASA1,RB1,CLIP4,SETDB2,RNF4,UGT2A3,MPHOSPH9,RUBCNL,ALKAL2,SLC30A6,IVNS1ABP,ARHGEF40,ZNF605,SLC12A2,WDCP,EFR3B,GABRA2,KDM5B,RAPGEF6,CENPJ,ERAP1,SRP72,ERBIN,NPFFR2,INSM2,ADGRL3,DOCK9,NT5C1B,TFDP1,TGFBI,GTF2H3,HEXB,TADA2B,SPTSSA,ZMYM2,TMEM178A,RMST,IFT88,LOX" MicroRNA hsa-miR-376a*:mirSVR_highEffct hsa-miR-376a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.87E-22 4.72E-18 6.69E-21 6.12E-20 55 986 "NLN,SLAMF6,COG6,ARHGAP5,ATP7B,CBLN3,CAST,FCHO2,ITGBL1,AKAP6,SYCP3,NGDN,TTC37,DNM3,SREK1,COG3,TBC1D4,PTPRC,PTPRH,SACS,G3BP2,PARPBP,EIF2D,DRAM1,ARSK,DLEU1,CLIP1,FCAR,SULT6B1,FNIP1,VEZT,BRMS1L,UFM1,ZNF605,TNFSF13B,SLC22A5,YPEL5,MEGF10,GABRA2,PDS5B,MCCC2,PPARGC1A,ADGRL3,ADGRA3,SPIC,STON1,NPL,RXFP2,PAPPA2,ANKS1B,ZMYM2,LINC00272,FIP1L1,NUAK2,TTC7A" MicroRNA hsa-miR-137:mirSVR_lowEffct hsa-miR-137:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.42E-22 5.01E-18 7.10E-21 6.50E-20 71 1622 "MAP1B,TMEM132B,KIAA1211,RGS5,MSH2,ARHGAP5,FAM193A,AACS,NCOA1,PAH,PCDH9,PDE4D,SMIM14,THAP6,HOMER1,AKAP6,TOGARAM2,LYSMD3,PREPL,CRHBP,TTC37,FCRL2,DCAF8,MATR3,EPS8L1,PIGG,COG3,PTPRC,SUPT7L,NR1H4,RGS4,TMEM33,CLIP4,PACRGL,RNF4,FAM172A,DEPDC4,SH3YL1,GORAB,POLK,PEAR1,FBXO11,NUBPL,THADA,FSHR,CYP1B1-AS1,EAPP,NPAS3,NFASC,NMU,STRN,GOLGA3,DOCK9,XPO4,RNF17,CRB1,HAL,TECRL,POC5,ZNF876P,TENT2,WDR36,YTHDC2,IGF1,JCHAIN,TADA2B,ZBTB41,SDR39U1,FIP1L1,AMTN,LMNB1" MicroRNA hsa-miR-877:mirSVR_lowEffct hsa-miR-877:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.60E-22 5.10E-18 7.22E-21 6.61E-20 69 1538 "SMIM15,TMEM132B,KIAA1211,SLAMF6,EP400,BLZF1,WDR19,FAM193A,ASTN1,CENPBD1P1,SLC4A4,BCL2L2,NEDD8,AP1G2,PNP,CDKL2,CD1D,ZMYM5,PDE4D,PIGR,LINC01085,SNX6,THAP6,AKAP6,GNPTAB,SNCAIP,FAM169A,DNM3,CMTM5,EIF2AK2,BIVM,PIGG,GNPDA2,TMEM161B,EFNA5,RNF4,SPATA9,FAM172A,ARSK,IRF9,FCGR3B,FOXO1,SLC8A1,SLC12A2,SLC15A4,C1orf112,FSHR,EFR3B,CD244,ERAP1,NPAS3,NFASC,SULT1E1,PPIP5K2,ADGRA3,GPR12,TDG,CRB1,AP4S1,RAB2B,TENT2,WDR36,PLB1,CCDC190,IRF1,ZBTB41,LHX9,AXDND1,IFT88" MicroRNA hsa-miR-450b-3p:mirSVR_lowEffct hsa-miR-450b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-21 5.35E-18 7.56E-21 6.92E-20 64 1334 "MATN3,ADORA1,EP400,MSH2,ZNF784,ASTN1,CENPBD1P1,CCNB1IP1,SLC4A4,STARD13,NEDD8,ARHGEF7,LINC02347,TAF1B,PCCA,CDK18,PDE4D,CHD1,LINC01085,HECTD1,THAP6,TOGARAM2,HEATR5A,CLOCK,SPATA18,LOC439933,OCIAD1,PTPRH,GUSBP3,EFNA5,EIF2B1,CWC27,SAP18,ETF1,F10,FCAR,TNFRSF19,PIBF1,HSD17B7,SLC8A1,POTEM,EFR3B,CYP1B1-AS1,CIDEB,PDS5B,TMEM183A,HSPH1,MAST4,METAP2,TCF7,STON1,TXK,VRK2,WDR36,NSD2,ZNF10,MZF1,GALP,CAB39L,KIF2A,AMTN,DNAH10,SPRYD7,LMNB1" MicroRNA hsa-miR-422a:mirSVR_lowEffct hsa-miR-422a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-21 5.38E-18 7.59E-21 6.95E-20 73 1710 "ADD1,ADORA1,ANKRD34B,AACS,CENPBD1P1,NFATC4,ARHGEF7,CCNA1,LINC02347,NOVA1,MPZL1,SNTG2,ZNF664,PCCA,PCDH9,DCLK1,ZMYM5,WDFY2,MRPL57,CLOCK,UBXN2A,DHFR,NR1H4,GALNT14,FAM129A,ATG10,RNF31,RASA1,RB1,ZNF419,SETDB2,MBNL2,SLC22A17,FCGR3B,TACC3,SUCO,PEAR1,SH3BP2,DDX51,PAICS,ZNF446,STPG4,ARHGEF40,WDCP,ACIN1,NMNAT2,RAPGEF6,ZNF274,UHRF1BP1L,NFASC,MCCC2,IKBIP,DHRS4,BRD8,ZNF544,ANO4,TCF7,TEP1,GRSF1,ZBTB49,BAZ1A,RAB2B,TMEM174,KCNT2,ZNF324B,CCDC169,PLB1,LHX9,ZBED3-AS1,EP400P1,RNASE11,LETM1,RMST" MicroRNA hsa-miR-192*:mirSVR_highEffct hsa-miR-192*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-21 5.44E-18 7.66E-21 7.01E-20 53 917 "ANKRD34B,CUL4A,ARL1,CCNB1,PCCA,ZMYM5,CDK17,RCBTB2,ZNF595,PGGT1B,TSTD1,SMIM14,ATAD2B,THAP6,AKAP6,TAPT1,CLOCK,VCAN,MATR3,BIVM,SPATA18,PTGS2,SLC35F6,PARPBP,TSEN15,NR1H4,DTD2,SNORA53,STK32B,USP44,TRAPPC13,FCAR,UTP15,GORAB,PIBF1,SUCO,NBEA,NUBPL,THADA,C1orf112,ERAP1,ATP8A2,PSME4,TMED2,METAP2,TFDP1,NPL,TXK,ZNF876P,WDR36,NSD2,FAM151B,DIAPH3" MicroRNA hsa-miR-624*:mirSVR_lowEffct hsa-miR-624*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-21 5.47E-18 7.69E-21 7.04E-20 62 1255 "BIRC6,NLN,MCFD2,ZNF542P,NFATC4,SCARB1,UHMK1,PCDH9,XPR1,CENPC,PIWIL1,SNX6,PTPRVP,THAP6,TAPT1,PREPL,FAM169A,DDX59,TSEN15,NR1H4,DNMT3A,EGLN3,B3GLCT,TMEM33,MARVELD2,FAM172A,ETF1,ABCA11P,GMPR2,SUCO,FOXO1,VEZT,IVNS1ABP,POTEM,CGREF1,SLC22A5,CYP1B1-AS1,MYO16,GABRA2,KDM5B,NMNAT2,KDM3B,NEDD1,ERBIN,PPARGC1A,BRD8,MTUS2,TCF7,NT5C1B,CRB1,MSH6,RAB2B,HSP90B1,UBE2K,SLAIN1,VRK2,HTR2A,WDR36,KCNT2,C12orf73,CCDC190,NUAK2" MicroRNA hsa-miR-15a*:mirSVR_lowEffct hsa-miR-15a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-21 5.70E-18 8.00E-21 7.33E-20 65 1376 "RALGAPA1,NLN,CUL4A,FBRSL1,CENPBD1P1,BCL2L2,NFATC4,ARHGEF7,MPZL1,CAST,PDE4D,PGGT1B,TM9SF2,SMIM14,JAKMIP1,THAP6,TAPT1,COPA,C12orf65,NOS1AP,DCAF8,EGLN3,B3GLCT,ZNF419,POLR1D,TXNDC15,UGT2A3,ELF1,MPHOSPH9,ARSK,STK32B,TOMM40L,SDC1,STAB2,THADA,SLC12A2,SLC22A4,UGGT2,PDS5B,JPH4,RAPGEF6,NAAA,ZNF274,HSPH1,NFASC,RBKS,NEDD1,GJB2,LINC02393,PPIP5K2,ANO4,TCF7,BAZ1A,HEXB,WDR36,STARD4,NSD2,SELENOI,IL6ST,FIP1L1,TTC41P,LINC01913,LINC00442,SPRYD7,PABPN1" MicroRNA hsa-miR-3166:mirSVR_highEffct hsa-miR-3166:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-21 6.00E-18 8.41E-21 7.70E-20 53 919 "CDKL4,NCOA1,CADM3,NFATC4,ARHGEF7,CD1E,ZMYM5,WDFY2,CKMT2,EPGN,LYSMD3,PREPL,SNCAIP,UBXN2A,IFT172,PTGS2,F11R,G3BP2,GNPDA2,ZNF329,KIRREL1,LGR6,MARVELD2,ARSK,ADGRV1,FCAR,UTP15,FGF9,SUCO,FLT3,BRMS1L,SLC22A5,YPEL5,MYT1L,PDS5B,RAPGEF6,NAAA,UHRF1BP1L,ERBIN,C5orf56,CRB1,MAEL,HMGCR,HPCAL1,ZNF876P,ZFHX2,ZNF324B,SDR39U1,CHPT1,ANKDD1B,KIR2DL4,KIR2DS4,LOX" MicroRNA hsa-miR-15a:mirSVR_highEffct hsa-miR-15a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.16E-21 6.16E-18 8.63E-21 7.90E-20 67 1460 "RGS5,SLC4A4,ATP4B,MYBPC1,PPP1R12B,BCL2L2,CACNA1E,CAMK4,CAST,CD1D,PCDH9,CDK17,PDE4D,GLT1D1,GPR180,ITGBL1,CFAP54,CFAP45,JAKMIP1,THAP6,PREPL,IL20,LRRTM2,FCRL2,DCAF8,PIGG,COCH,TMEM161B,DTD2,CLIP4,LATS2,MBNL2,TBC1D19,ABCA11P,FGF9,SUCO,FLT3,RUBCNL,BRMS1L,IVNS1ABP,ARHGEF40,SLC15A4,SLC22A4,MYT1L,ERAP1,NPAS3,NFASC,LRCH1,PCDH17,INSM2,ADGRL3,RNF212,COP1,NT5C1B,FZD10,ADAMTS19,GPN1,HTR2A,ANKS1B,ZMYM2,CHPT1,KIF2A,KIR2DS4,LINC01913,LCP1,RMST,SPRYD7" MicroRNA hsa-miR-182*:mirSVR_lowEffct hsa-miR-182*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-21 6.46E-18 9.04E-21 8.28E-20 60 1181 "ATP6V1G3,ANKRD34B,SEMA6A,FBRSL1,CDKL4,CCDC181,FCRL3,ARHGEF7,CCNA1,CD1D,NFXL1,ZMYM5,PCSK1,PDGFRA,PGGT1B,JAKMIP1,LYSMD3,PREPL,SNCAIP,DNM3,FCRL5,ZNF586,PIGG,DMXL1,GNPDA2,MTX3,C12orf42,C14orf119,NR1H4,RAN,RB1,MEMO1,POLR1D,NTN4,ELF1,FGF9,SDC1,MROH9,FLT1,SLC34A2,NBEA,UFM1,PDS5B,KDM5B,ATP8A2,KLHL20,SCFD1,RNF17,SLC7A8,ATP6V0A2,HSD17B4,WDR36,ZNF26,JCHAIN,ANKS1B,FAM151B,CAB39L,EP400P1,NUAK2,SPRYD7" MicroRNA hsa-miR-129-3p:mirSVR_highEffct hsa-miR-129-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.28E-21 6.79E-18 9.48E-21 8.68E-20 41 530 "IL17D,NDRG2,BIRC6,NLN,SLC5A6,PCCA,CFAP54,HECTD1,GNPTAB,POU2F1,FCRL5,COG3,DMXL1,SACS,SUPT7L,EGLN3,FAM129A,RB1,TMEM161B,RGS12,MEMO1,PACRGL,BORA,FCAR,POLK,VEZT,JPH4,HSPH1,KDM3B,ERBIN,KLHL20,ZBTB37,TCF7,CRB1,GTF2H3,FZD10,TNR,STARD4,YTHDC2,CHPT1,TTC41P" MicroRNA hsa-miR-593*:mirSVR_lowEffct hsa-miR-593*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-21 6.88E-18 9.53E-21 8.73E-20 74 1761 "LRRC43,NDRG2,ADD1,EP400,APC,ATP1A2,B4GALT3,BCL2L2,NFATC4,PNP,XPR1,CDK18,WDFY2,COLEC11,PKP1,THAP6,SNCAIP,DNM3,DCAF8,PIGG,SREK1,SUPT7L,WDR1,DNMT3A,EFNA5,GRTP1,SNORA53,BORA,PCGF3,TMEM129,SPON2,FGF9,POLK,SUCO,FOXG1,PEAR1,FOXO1,VEZT,BRMS1L,ZNF446,ARHGEF40,SLC22A4,CHFR,DCAF11,CYP1B1-AS1,JPH4,TMEM183A,ATP8A2,NFASC,RBKS,MCCC2,IKBIP,GJB2,PPIP5K2,CNTN2,ADGRA3,DOCK9,NCSTN,TFDP1,SLC7A8,TXK,SLAIN1,MZF1,TADA2B,PGAM5,ZBED3-AS1,KCNJ9,LMLN,KIR2DL4,KIR3DL1,NUAK2,TTC7A,PABPN1,ZNF304" MicroRNA hsa-miR-30d-5p:TargetScan hsa-miR-30d-5p TargetScan 1.29E-21 6.88E-18 9.53E-21 8.73E-20 59 1144 "ABL2,MDM4,BIRC6,KIAA1211,PITPNM2,NOVA1,CAMK4,PDE4D,CFL2,CHD1,PGGT1B,GPR180,ATAD2B,PITX1,LYSMD3,CLOCK,MATR3,CEP350,SACS,G3BP2,RABGAP1L,DNMT3A,RASA1,POLR1D,PACRGL,LATS2,MBNL2,ELK3,PCGF3,FOXG1,N4BP2,NR5A2,CHFR,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,JPH4,KLHL20,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ANO4,EML4,KHNYN,GPR161,BAZ1A,RIMBP2,KLF12,GUF1,DCP2,LHX9,FAM49A,LMLN,KIF3C,LOX" MicroRNA hsa-miR-30a-5p:TargetScan hsa-miR-30a-5p TargetScan 1.29E-21 6.88E-18 9.53E-21 8.73E-20 59 1144 "ABL2,MDM4,BIRC6,KIAA1211,PITPNM2,NOVA1,CAMK4,PDE4D,CFL2,CHD1,PGGT1B,GPR180,ATAD2B,PITX1,LYSMD3,CLOCK,MATR3,CEP350,SACS,G3BP2,RABGAP1L,DNMT3A,RASA1,POLR1D,PACRGL,LATS2,MBNL2,ELK3,PCGF3,FOXG1,N4BP2,NR5A2,CHFR,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,JPH4,KLHL20,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ANO4,EML4,KHNYN,GPR161,BAZ1A,RIMBP2,KLF12,GUF1,DCP2,LHX9,FAM49A,LMLN,KIF3C,LOX" MicroRNA hsa-miR-30b-5p:TargetScan hsa-miR-30b-5p TargetScan 1.29E-21 6.88E-18 9.53E-21 8.73E-20 59 1144 "ABL2,MDM4,BIRC6,KIAA1211,PITPNM2,NOVA1,CAMK4,PDE4D,CFL2,CHD1,PGGT1B,GPR180,ATAD2B,PITX1,LYSMD3,CLOCK,MATR3,CEP350,SACS,G3BP2,RABGAP1L,DNMT3A,RASA1,POLR1D,PACRGL,LATS2,MBNL2,ELK3,PCGF3,FOXG1,N4BP2,NR5A2,CHFR,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,JPH4,KLHL20,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ANO4,EML4,KHNYN,GPR161,BAZ1A,RIMBP2,KLF12,GUF1,DCP2,LHX9,FAM49A,LMLN,KIF3C,LOX" MicroRNA hsa-miR-30c-5p:TargetScan hsa-miR-30c-5p TargetScan 1.29E-21 6.88E-18 9.53E-21 8.73E-20 59 1144 "ABL2,MDM4,BIRC6,KIAA1211,PITPNM2,NOVA1,CAMK4,PDE4D,CFL2,CHD1,PGGT1B,GPR180,ATAD2B,PITX1,LYSMD3,CLOCK,MATR3,CEP350,SACS,G3BP2,RABGAP1L,DNMT3A,RASA1,POLR1D,PACRGL,LATS2,MBNL2,ELK3,PCGF3,FOXG1,N4BP2,NR5A2,CHFR,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,JPH4,KLHL20,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ANO4,EML4,KHNYN,GPR161,BAZ1A,RIMBP2,KLF12,GUF1,DCP2,LHX9,FAM49A,LMLN,KIF3C,LOX" MicroRNA hsa-miR-30e-5p:TargetScan hsa-miR-30e-5p TargetScan 1.29E-21 6.88E-18 9.53E-21 8.73E-20 59 1144 "ABL2,MDM4,BIRC6,KIAA1211,PITPNM2,NOVA1,CAMK4,PDE4D,CFL2,CHD1,PGGT1B,GPR180,ATAD2B,PITX1,LYSMD3,CLOCK,MATR3,CEP350,SACS,G3BP2,RABGAP1L,DNMT3A,RASA1,POLR1D,PACRGL,LATS2,MBNL2,ELK3,PCGF3,FOXG1,N4BP2,NR5A2,CHFR,LIMCH1,GABRB1,KIF21B,PDS5B,KDM5B,JPH4,KLHL20,PCDH17,PPARGC1A,PPIP5K2,METAP2,CNTN2,ANO4,EML4,KHNYN,GPR161,BAZ1A,RIMBP2,KLF12,GUF1,DCP2,LHX9,FAM49A,LMLN,KIF3C,LOX" MicroRNA hsa-miR-29b:mirSVR_highEffct hsa-miR-29b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.32E-21 7.04E-18 9.74E-21 8.92E-20 61 1222 "SFTA3,SLAMF6,SNX24,APC,CDKL2,MPZL1,CD1D,SNTG2,SLC5A8,PDGFRA,CFAP54,ATAD2B,THAP6,LYSMD3,DCAF8,IFT172,SREK1,LOC439933,DNMT3A,RB1,ARGLU1,POLR1D,RNASEL,EFNA5,ETF1,FMO1,NUBPL,SLC12A2,C1orf112,CHFR,MYO16,KDM5B,NAAA,TMEM183A,UHRF1BP1L,OXGR1,NPAS3,CMPK2,RBKS,MCCC2,LRCH1,PSME4,PPIP5K2,METAP2,ADGRA3,EML4,KMT5A,KMT5C,TDG,FCRLA,NPL,ADAMTS19,GPN1,HMGCR,HTR2A,IGF1,EP400P1,RILPL2,NUAK2,IFT88,LOX" MicroRNA hsa-miR-30b*:mirSVR_highEffct hsa-miR-30b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-21 7.30E-18 1.01E-20 9.23E-20 54 959 "STXBP6,NCOA1,ATP7B,CD84,ARHGEF7,AP1G2,LDB2,ZNF595,THAP6,POU2F1,SNCAIP,CSNK1G3,CMTM5,FCRL5,FBXL5,NUDT12,SACS,PPP2R3C,NR1I3,DNMT3A,ATG10,RB1,AASDH,RGS4,EFNA5,MARVELD2,GMPR2,IRF9,FCAR,FNIP1,FOXG1,ZCCHC8,PKD2L2,CGREF1,ZNF667,MYO16,ATP8A2,NPAS3,LRCH1,KLHL20,SULT1E1,MAST4,UTP20,ACSL6,SLC7A8,AP4S1,IGSF8,ZFHX2,ANKS1B,FAM151B,TMEM178A,FAM71C,SPRYD7,CDK2AP1" MicroRNA hsa-miR-202:mirSVR_lowEffct hsa-miR-202:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.67E-21 8.88E-18 1.23E-20 1.12E-19 63 1307 "MDM4,NLN,COG6,MIPEP,APAF1,AACS,SYT2,PCDH9,ZMYM5,NUP37,THAP6,HOMER1,COPA,GNPTAB,THTPA,POU2F1,KIAA0040,MPHOSPH8,DCAF8,SNX17,GNPDA2,PARPBP,CLIP4,MEMO1,TXNDC15,SNORA53,ELF1,CLIP1,SH3YL1,TRAPPC13,PCBD2,TOMM40L,SPON2,GORAB,FOXG1,STAB2,BRMS1L,P2RX2,PDS5B,HSPH1,SRP54,RBKS,LRCH1,BRD8,UGT2A1,PPIP5K2,METAP2,ACSL6,EML4,NPL,ADAMTS19,ARHGAP30,TENT2,WDR36,ZNF26,ZMYM2,TDRD3,ZBED3-AS1,CHPT1,LMLN,DIAPH3,SPRYD7,AXDND1" MicroRNA hsa-miR-628-5p:mirSVR_lowEffct hsa-miR-628-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-21 8.93E-18 1.23E-20 1.13E-19 71 1639 "RALGAPA1,ABL2,LRRC43,TMEM132B,NLN,EP400,ASTN1,ATP1A2,MYH6,MPZL1,CD1D,CD1E,SCARB1,DCLK1,MRPL57,CFAP54,TAPT1,SNCAIP,DNM3,SNX17,PSME1,PTGS2,OCIAD1,G3BP2,RABGAP1L,ATG10,RASA1,RGS12,TMEM33,PACRGL,EFNA5,EIF2B1,KIRREL1,DHRS2,ZNF671,DRAM1,SULT6B1,N4BP2L2,RELL1,PIBF1,POLK,HSD17B7,STAB2,IVNS1ABP,THADA,C1orf112,LIMCH1,MEGF10,GABRA2,KIF21B,PDS5B,ATP8A2,HSPH1,KDM3B,PPARGC1A,TMED2,PPIP5K2,MTUS2,ADGRL3,KMT5A,COX18,NT5C1B,ZBTB49,UBE2K,HMGCR,YTHDC2,PLB1,FAM151B,FIP1L1,LINC01913,LCP1" MicroRNA hsa-miR-125b-2*:mirSVR_highEffct hsa-miR-125b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-21 9.35E-18 1.29E-20 1.18E-19 58 1113 "ATP2B4,BTF3,CAST,PCDH9,ZMYM5,RGSL1,PDE4D,CENPC,TSTD1,THAP6,PMCH,GNPTAB,CSNK1G3,BIVM,SREK1,COG3,KLHL3,WDR1,PARPBP,CLIP4,MEMO1,POLR1D,EFNA5,ELF1,MARVELD2,TCTN2,FAM172A,CLIP1,USP44,GORAB,VEZT,IVNS1ABP,ZNF605,SLC12A2,SLC22A4,SNRPF,MYO16,GABRB1,NAAA,TMEM183A,ERAP1,NPAS3,MRPS27,ERBIN,ZNF544,UGT2A1,TMED2,MTUS2,EML4,CRB1,GTF3C2,RIMBP2,HEXB,HMGCR,GUF1,LHX9,FAM49A,LCP1" MicroRNA hsa-miR-655:PITA hsa-miR-655:PITA_TOP PITA 1.80E-21 9.55E-18 1.31E-20 1.20E-19 49 789 "MATN3,BIRC6,ADD1,APC,ARHGAP5,FAM193A,ASCL1,NCOA1,ATP2B4,ARHGEF7,CDK17,ZNF595,HECTD1,HOMER1,STRN3,CEP135,PRKD1,ZFYVE16,SREK1,COG3,CEP350,TMEM161B,SMC6,RGS4,MEMO1,MBNL2,TRAPPC12,ETF1,FNIP1,FOXO1,SFSWAP,FBXO11,ALKAL2,PAICS,MEGF10,HSPH1,PCDH17,STRN,ADGRL3,DOCK9,ZBTB49,BAZ1A,ADAMTS19,KLF12,UBE2K,HMGCR,ZNF470,RILPL2,CDK2AP1" MicroRNA hsa-miR-4315:mirSVR_lowEffct hsa-miR-4315:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.87E-21 9.97E-18 1.37E-20 1.25E-19 50 824 "SFTA3,KIAA1211,CENPBD1P1,STARD13,BCL2L2,BTF3,CAST,CD1E,UHMK1,GLT1D1,POU2F1,NCOR2,SNCAIP,ITSN2,F11R,RABGAP1L,GNPDA2,WDR1,DNMT3A,TMEM161B,ELK3,CWC27,TRAPPC13,FCGR3A,FCGR3B,GORAB,PIBF1,POLK,SUCO,NR5A2,YPEL5,CYP1B1-AS1,TMEM183A,CD244,DRC1,LRCH1,IKBIP,PPARGC1A,TBC1D1,ADGRA3,ARHGEF28,TEP1,RIMBP2,YTHDC2,KCNT2,PGAM5,TMEM178A,CAB39L,RMST,LMNB1" MicroRNA hsa-miR-499-5p:mirSVR_highEffct hsa-miR-499-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.15E-21 1.14E-17 1.57E-20 1.43E-19 61 1234 "SMIM15,MDM4,KIAA1211,STXBP6,NOVA1,CDKL2,CFL2,GPR180,HECTD1,GNPTAB,PREPL,VCAN,ITSN2,FCRL5,COCH,PTPRC,GNPDA2,B3GLCT,RB1,ARGLU1,SMC6,DTD2,POLR1D,ELK3,TCTN2,FAM172A,DLEU1,ABCA11P,FGF9,FOXG1,FLT3,VEZT,UFM1,IVNS1ABP,ZNF605,SLC12A2,WDCP,NR5A2,LIMCH1,GABRA2,CIDEB,KDM3B,MCCC2,IKBIP,COMMD6,PPARGC1A,STON1,EML4,TDG,NT5C1B,LINC01551,ZNF721,NPL,ADAMTS19,DCP2,ZNF26,KCNT2,ZNF470,C12orf73,NPHS2,AMTN" MicroRNA hsa-miR-92b:mirSVR_highEffct hsa-miR-92b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.33E-21 1.24E-17 1.70E-20 1.55E-19 51 863 "MAP1B,KIAA1211,PITPNM2,CDKL4,ATP2B4,STARD13,NOVA1,FCHO2,CD1D,ZNF595,GPR180,NUP37,JAKMIP1,HECTD1,STRN3,CRHBP,C12orf65,ZNF586,COG3,DMXL1,G3BP2,FAM129A,LAP3,LATS2,RNF4,ABCA11P,PCGF3,USP44,FNIP1,POLK,BRMS1L,ALKAL2,NUBPL,ZNF605,SLC12A2,PDS5B,NAAA,IQGAP2,NPAS3,RBKS,LRCH1,ZNF544,GOLGA3,ANO4,DOCK9,FZD10,ZNF721,TENT2,KCNT2,AXDND1,LMNB1" MicroRNA hsa-miR-556-5p:mirSVR_highEffct hsa-miR-556-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-21 1.24E-17 1.70E-20 1.55E-19 55 1007 "RALGAPA1,WDR35,ULK1,MCFD2,APC,STXBP6,AACS,ATP2B4,SLC5A6,CCNA1,TAF1B,MPZL1,UHMK1,PCCA,PDE4D,PIWIL1,ITGBL1,STRN3,LYSMD3,CSNK1G3,PRKD1,ZNF586,NUDT12,TBC1D4,SACS,G3BP2,PARPBP,RB1,TMEM161B,NTN4,GMPR2,RELL1,UFM1,SCYL2,MRPS14,LIMCH1,TMEM183A,MRPS27,CMPK2,DRC1,NPFFR2,GJA3,UTP20,CNTN2,ARHGEF28,RNF212,RASSF6,TMPO,GPN1,TXK,SLAIN1,VRK2,ZBTB41,FIP1L1,PABPN1" MicroRNA hsa-miR-298:mirSVR_highEffct hsa-miR-298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-21 1.25E-17 1.70E-20 1.56E-19 60 1197 "MATN3,NDRG2,ADD1,NLN,UVSSA,NCOA1,MYBPC1,ARHGEF7,CCNA1,ADGRD1,NRL,CAST,FCHO2,FCRLB,PCCA,PCDH9,PMCH,TOGARAM2,EPGN,MATR3,BIVM,TINF2,G3BP2,C14orf119,RB1,CLIP4,POLR1D,CRYL1,PACRGL,ELF1,TBC1D19,ADGRV1,F7,PIBF1,SUCO,TM9SF1,RUBCNL,FBXO11,CCDC92,IVNS1ABP,N4BP2,GABRB1,NAAA,DRC1,NEDD1,PPARGC1A,MAST4,ZNF544,UGT2A1,INSM2,STON1,ACTR6,TMEM174,ZNF140,ZMYM2,TDRD3,KCNN2,RMST,AXDND1,SPATA13" MicroRNA hsa-miR-4314:mirSVR_lowEffct hsa-miR-4314:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-21 1.28E-17 1.75E-20 1.60E-19 76 1869 "TMEM132B,ADORA1,NLN,SLAMF6,NYNRIN,DHX37,ARHGAP5,CENPBD1P1,ZNF542P,MYBPC1,CD84,FCRL3,RAB29,CBLN3,RILPL1,ZNF664,FAM177A1,PDGFRA,COLEC11,ATAD2B,LTB4R,PTPRVP,THAP6,POU2F1,EPGN,SNCAIP,DNM3,KIAA0040,NOS1AP,CEP350,GNPDA2,MTX3,PPP2R3C,FAM129A,CLIP4,EIF2D,DHRS2,ETF1,DNAJC27,ADGRV1,PCGF3,N4BP2L2,FLT3,STAB2,SUPT20H,VEZT,FBXO11,ZNF605,WDCP,LIMCH1,KDM5B,NMNAT2,TMEM183A,CD244,ATP8A2,NPAS3,SRP72,ANKLE2,MAST4,MTUS2,GOLGA3,ANO4,DOCK9,ZBTB49,TMPO,VRK2,TADA2B,ZNF470,ZNF84,LHX9,ZBED3-AS1,CAB39L,TTC41P,LINC00442,SPRYD7,TTC7A" MicroRNA hsa-miR-4289:mirSVR_highEffct hsa-miR-4289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.60E-21 1.39E-17 1.88E-20 1.73E-19 49 796 "MATN3,WDR35,CUL4A,ASCL1,AACS,ZNF542P,LDB2,CD1D,PCK2,CFL2,RCBTB2,MRPL57,CFAP54,THAP6,C1orf116,VCAN,LRRTM2,MPHOSPH8,ZFYVE16,SPATA18,DMXL1,CEP350,RABGAP1L,EGLN3,LAP3,NTN4,LATS2,SAP18,DLEU1,ABCA11P,CLIP1,THADA,TMEM132D,FSHR,LIMCH1,ERAP1,LILRB1,BRD8,LILRB4,KMT5A,DOCK9,FCRLA,RIMBP2,TPO,TECRL,DCP2,YTHDC2,ZMYM2,ZBED3-AS1" MicroRNA hsa-miR-4291:mirSVR_highEffct hsa-miR-4291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-21 1.41E-17 1.91E-20 1.75E-19 54 973 "MAP1B,LRRC43,MDM4,COG6,MSH2,SLC4A4,BCL2L2,ODC1,PGGT1B,LINC01085,HOMER1,LYSMD3,CSNK1G3,VCAN,MATR3,COG3,PTGS2,LOC439933,SUPT7L,RB1,ARGLU1,TMEM161B,DTD2,SETDB2,EFNA5,TBC1D19,FAM172A,CWC27,N4BP2L2,HSD17B7,BRMS1L,IVNS1ABP,SLC12A2,GABRA2,MYT1L,KIF21B,PDS5B,PCDH17,PPARGC1A,STRN,ZNF544,ATP11A,PPIP5K2,COP1,TMPO,RIMBP2,HEXB,ADAMTS19,TMEM174,DCP2,FAM49A,TTC41P,MFSD2B,PABPN1" MicroRNA hsa-miR-324-3p:mirSVR_lowEffct hsa-miR-324-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.66E-21 1.42E-17 1.92E-20 1.76E-19 77 1917 "NDRG2,ACOX3,ADORA1,KIAA1211,CUL4A,APBB2,WDR19,CCDC181,CADM3,ATP7B,BCL2L2,NFATC4,CAD,LDB2,NFXL1,SCFD2,NRXN1,ATAD2B,PTPRVP,THAP6,C1orf116,STRN3,FAM53A,SNCAIP,SNX17,G3BP2,DNMT3A,GALNT14,FAM129A,ZNF329,OGFOD2,AASDH,CLIP4,EFNA5,KIRREL1,DHRS2,ZNF671,EFS,STK32B,DLEU1,ABCA11P,SLC22A17,USP44,TMEM129,SLC34A2,PLEKHA6,P2RX2,NR5A2,CHFR,EFR3B,PUS1,DCAF11,GABRB1,KIF21B,PDS5B,NMNAT2,JPH4,TMEM183A,LILRB1,KLHL20,GJB2,BRD8,MAST4,ANO4,NPL,KLF12,UBE2K,LTB4R2,NSD2,ZNF470,PLB1,ZBTB41,KCNJ9,KIF3C,LAD1,SPRYD7,PABPN1" MicroRNA hsa-let-7a-2*:mirSVR_highEffct hsa-let-7a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.96E-21 1.57E-17 2.13E-20 1.95E-19 61 1242 "RALGAPA1,BIRC6,TBC1D14,CUL4A,SNX24,CENPBD1P1,FCRL3,BTF3,NFKBIA,CAD,CCNB1,PCSK1,PDGFRA,CENPC,ATAD2B,THAP6,HOMER1,COG3,CEP350,PTPRC,DNMT3A,FAM129A,B3GLCT,RB1,IPO4,SETDB2,MBNL2,TRAPPC13,LRRN2,RELL1,SDC1,HSD17B7,G2E3,NBEA,PLEKHA6,MBIP,PAICS,IVNS1ABP,C1orf112,SLC22A4,GABRA2,MYT1L,GABRB1,GAK,ERBIN,PPARGC1A,TBC1D1,UGT2A1,UTP20,TMED2,ADGRL3,DOCK9,COX18,LINC01551,BAZ1A,TMPO,NPL,ZNF10,ZMYM2,MFSD2B,RMST" MicroRNA hsa-miR-1258:mirSVR_lowEffct hsa-miR-1258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-21 1.79E-17 2.42E-20 2.21E-19 62 1285 "NDRG2,SLAMF6,COG6,MCFD2,APBB2,MSH2,ARHGAP5,SLC4A4,STARD13,FCRL3,BTF3,ADGRD1,CACNA1E,CAST,CD1D,CDK17,PDGFRA,PIK3C2B,KIAA0040,MPHOSPH8,FCRL5,COG3,CEP350,PARPBP,C14orf119,MEMO1,TXNDC15,DHRS2,FAM172A,PCGF3,F10,ELOVL7,FLT1,FMO1,ZNF605,SLC12A2,MEGF10,UHRF1BP1L,ATP8A2,HSPH1,MCCC2,LRCH1,KLHL20,COX18,CRB1,AP4S1,GTF2H3,RASSF6,ACTR6,RIMBP2,ATP6V0A2,ZNF876P,TENT2,ZFHX2,IL6ST,PLB1,FAM49A,CHPT1,AMTN,LINC00442,AXDND1,LMNB1" MicroRNA hsa-miR-106b-5p:Functional MTI Functional MTI miRTarbase 3.50E-21 1.86E-17 2.51E-20 2.30E-19 57 1091 "MCC,ADD1,ULK1,APC,ARL1,PPP1R12B,BCL2L2,ARHGEF7,FCHO2,CFL2,PFKFB2,THAP6,GNPTAB,LYSMD3,CLOCK,BRI3BP,C12orf65,UBXN2A,DCAF8,ZFYVE16,FBXL5,OCIAD1,SACS,RABGAP1L,GNPDA2,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,ELK3,ETF1,DNAJC27,IRF9,N4BP2L2,SUCO,BRMS1L,ZNF446,THADA,ACIN1,GAK,ERAP1,KLHL20,COMMD6,ZBTB37,MSH6,GTF2H3,TMPO,TXK,UBC,NSD2,TADA2B,ZDHHC20" MicroRNA hsa-miR-3128:mirSVR_highEffct hsa-miR-3128:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.13E-21 2.19E-17 2.96E-20 2.71E-19 56 1057 "MDM4,NLN,FAM193A,AACS,BCL2L2,RAB29,CACNA1E,CAST,FCHO2,UHMK1,PCDH9,PDE4D,PFKFB2,PGGT1B,NRXN1,HOMER1,TOGARAM2,HEATR5A,PREPL,CTSG,LOC439933,COCH,PTPRC,DHFR,DNMT3A,EGLN3,CLIP4,TXNDC15,MBNL2,DHRS2,TBC1D19,FAM172A,GORAB,FLT1,VEZT,CCDC88A,SLC12A2,UGGT2,LIMCH1,GABRA2,PDS5B,NPAS3,GC,SULT1E1,METAP2,KMT5A,C1QTNF9B,COX18,TGFBI,MSH6,ADAMTS19,GUF1,TADA2B,ZNF470,ZMYM2,RMST" MicroRNA hsa-miR-124-3p.1:TargetScan hsa-miR-124-3p.1 TargetScan 4.24E-21 2.26E-17 3.04E-20 2.78E-19 62 1291 "ABL2,MAP1B,NYNRIN,FBRSL1,APBB2,ATP2B4,KCTD12,CACNA1E,MPZL1,RILPL1,FCHO2,FAM177A1,CDK18,PDE4D,CHD1,DHRS1,ATAD2B,AKAP6,FAM163A,POU2F1,LYSMD3,CLOCK,GALNT9,ITSN2,PRKD1,DMXL1,CEP350,F11R,G3BP2,MTX3,ARGLU1,MEMO1,EFNA5,DCUN1D2,ELK3,DRAM1,ETF1,CLIP1,N4BP2L2,PLEKHA6,ARHGEF40,CCDC88A,NR5A2,LIMCH1,GABRB1,KIF21B,IQGAP2,NFASC,ANKLE2,PCDH17,LPIN1,ATP11A,METAP2,GRSF1,RIMBP2,ATP6V0A2,ANKS1B,IRF1,LHX9,KIF2A,LAD1,LCP1" MicroRNA hsa-miR-514:mirSVR_highEffct hsa-miR-514:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-21 2.27E-17 3.05E-20 2.79E-19 50 840 "MATN3,NLN,ANKRD34B,CUL4A,MCFD2,MSH2,NCOA1,CAMK4,PCCA,FAM177A1,RGSL1,CENPC,ITGBL1,STRN3,HEATR5A,CSNK1G3,FAM169A,SPATA18,OCIAD1,RABGAP1L,C12orf42,PARPBP,NR1H4,DTD2,PACRGL,DLEU1,ELOVL7,RELL1,PIBF1,SUCO,PEAR1,FLT1,ZCCHC8,RUBCNL,ZNF667,NPAS3,NEDD1,IKBIP,STRN,INSM2,LINC02393,ADAM17,TCF7,TEP1,HMGCR,GUF1,RNASE11,AXDND1,LIG4,LOX" MicroRNA hsa-miR-154*:mirSVR_lowEffct hsa-miR-154*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.30E-21 2.29E-17 3.07E-20 2.81E-19 70 1624 "COG6,RGS5,APAF1,APC,NCOA1,NOVA1,MPZL1,CHAMP1,NFXL1,PCCA,RGSL1,PDGFRA,CENPC,GPR180,PIGR,PKP1,THAP6,HOMER1,AKAP6,SYCP3,CLOCK,FCRL5,FCRL2,SREK1,CEP120,PTPRC,RABGAP1L,PARPBP,PPP2R3C,RASA1,SLC9C2,RGS4,PACRGL,MBNL2,LGR6,MARVELD2,CWC27,PCGF3,PCBD2,FNIP1,PIBF1,FLT3,HSD17B7,FBXO11,NUBPL,SLC8A1,CCDC88A,PKD2L2,N4BP2,MEGF10,TMEM183A,HSPH1,OXGR1,KDM3B,IKBIP,MAST4,SCFD1,ADGRA3,GPR12,STON1,COX18,RNF17,FZD10,MAEL,WDR36,SELENOI,CCDC190,FIP1L1,LMNB1,ZNF304" MicroRNA hsa-miR-1208:mirSVR_highEffct hsa-miR-1208:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.71E-21 2.50E-17 3.36E-20 3.08E-19 56 1060 "RALGAPA1,COG6,CUL4A,MCFD2,BLZF1,AACS,ASTN1,CCDC181,ZNF542P,BTF3,CDKL2,ZMYM5,SNX6,HECTD1,HOMER1,AKAP6,STRN3,LYSMD3,PREPL,LACC1,ITSN2,BIVM,COG3,DHFR,PPP2R3C,DHRS2,DEPDC4,ARSK,ADGRV1,FGF9,RUBCNL,NBEA,THADA,CCDC88A,SLC22A5,LIMCH1,MYT1L,PDS5B,CENPJ,NAAA,ZNF274,HSPH1,GJB2,SCFD1,METAP2,ADGRL3,RASSF6,TMPO,RIMBP2,HEXB,TXK,ANKS1B,ZBTB41,FAM151B,CHPT1,AXDND1" MicroRNA hsa-miR-550:mirSVR_lowEffct hsa-miR-550:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.94E-21 2.63E-17 3.52E-20 3.22E-19 74 1803 "WDR35,CUL4A,PPFIA4,UVSSA,CDKL4,LINC02347,SCARB1,ADGRF3,THAP6,STRN3,COPA,KIAA0040,FCRL5,ZFYVE16,IFT172,SPATA18,COG3,GNPDA2,DHFR,SUPT7L,RABGGTA,RGS4,RGS12,LATS2,RNF4,KLHL12,MARVELD2,GP6,EFS,SAP18,STK32B,ABCA11P,GMPR2,PCGF3,POLK,SUCO,PEAR1,FLT3,GOLGA2P5,RUBCNL,PLEKHA6,PAICS,SLC30A6,THADA,ARHGEF40,TADA1,ZNF605,CGREF1,C1orf112,MEGF10,GABRA2,GABRB1,PDS5B,NMNAT2,GAK,ZNF274,NPAS3,KDM3B,CMPK2,NFASC,ZNF544,TBC1D1,STON1,COX18,RIMBP2,IL25,NSD2,ZFHX2,CHPT1,CAB39L,KIF3C,KIR2DL4,LAD1,IFT88" MicroRNA hsa-miR-212:mirSVR_highEffct hsa-miR-212:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.95E-21 2.63E-17 3.53E-20 3.23E-19 53 950 "KIAA1211,SEMA6A,SNX24,APAF1,CDKL4,MSH2,NOVA1,UHMK1,CFL2,CHD1,VIT,GPR180,JAKMIP1,LTB4R,HOMER1,FCRL5,PTGS2,PARPBP,TSEN15,RASA1,RB1,SETDB2,RNF4,UGT2A3,RUBCNL,SLC30A6,IVNS1ABP,ARHGEF40,ZNF605,SLC12A2,WDCP,EFR3B,LIMCH1,GABRA2,KDM5B,RAPGEF6,CENPJ,ERAP1,SRP72,ERBIN,NPFFR2,INSM2,ADGRL3,TFDP1,TGFBI,HEXB,TADA2B,SPTSSA,ZMYM2,TMEM178A,RMST,IFT88,LOX" MicroRNA hsa-miR-596:mirSVR_lowEffct hsa-miR-596:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.06E-21 2.69E-17 3.60E-20 3.30E-19 60 1216 "MCC,HOMEZ,APAF1,MSH2,FAM193A,ATP1A2,BCL2L2,CACNA1E,CBLN3,CD1D,SCARB1,NFXL1,FCRLB,CDK18,GLT1D1,PFKFB2,WDFY2,MRPL57,POU2F1,SNCAIP,CEP135,FAM169A,PIGG,COG3,KLHL3,B3GLCT,TXNDC15,KIRREL1,MAEA,CLIP1,SULT6B1,RELL1,STAB2,SLC34A2,IVNS1ABP,OXGR1,NFASC,SRP72,MAST4,PSME4,PPIP5K2,ADGRA3,RNF17,GRSF1,CRB1,GPR161,ZBTB49,AP4S1,ADAMTS19,GUF1,C12orf73,PLB1,ANKS1B,ZBED3-AS1,ANKDD1B,MFSD2B,LETM1,NUAK2,TTC7A,AXDND1" MicroRNA hsa-miR-1274a:mirSVR_highEffct hsa-miR-1274a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.94E-21 3.16E-17 4.22E-20 3.86E-19 42 583 "COG6,ARL1,NCOA1,NOVA1,CHD1,NRXN1,CSNK1G3,UBXN2A,FCRL5,G3BP2,NR1H4,B3GLCT,POLR1D,RNASEL,MBNL2,KIRREL1,GP6,STK32B,NDUFAF7,FGF9,SUPT20H,BRMS1L,ALKAL2,STPG4,THADA,TADA1,C1orf112,ZNF274,KDM3B,ANKLE2,NCSTN,TEP1,RASSF6,NPL,YTHDC2,CCDC169,SPTSSA,KCNJ9,KCNN2,FIP1L1,RMST,PABPN1" MicroRNA hsa-miR-3134:mirSVR_highEffct hsa-miR-3134:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.00E-21 3.19E-17 4.26E-20 3.90E-19 49 812 "ABL2,MAP1B,KIAA1211,UVSSA,CAST,RILPL1,CD1E,ZNF664,PCDH9,FAM177A1,ZNF595,GPR180,NRXN1,NUP37,THAP6,HOMER1,STRN3,RCHY1,LRRTM2,CEP135,FCRL5,SREK1,PTPRH,RABGAP1L,RASA1,DTD2,RNASEL,SPATA9,FAM172A,ELOVL7,FLT1,C1orf112,YPEL5,MYO16,ERAP1,CMPK2,NFASC,PCDH17,ANO4,LINC01551,HEXB,ZNF876P,PAPPA2,VRK2,ZNF10,ANKS1B,CHPT1,CAB39L,FAM71C" MicroRNA hsa-miR-449c*:mirSVR_lowEffct hsa-miR-449c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.33E-21 3.37E-17 4.49E-20 4.11E-19 52 919 "MCC,RGS5,ATP1A2,CADM3,PFKFB2,PGGT1B,THAP6,HOMER1,CSNK1G3,ITSN2,KIAA0040,KLHL3,TBC1D4,TINF2,PARPBP,RB1,RNASEL,LATS2,RNF4,DHRS2,ZNF671,MAEA,CLIP1,SUCO,G2E3,SLC30A6,WDCP,GABRB1,PDS5B,MRPS27,KLHL20,GJA3,ATP11A,ADAM17,ADGRA3,ACSL6,RNF212,NCSTN,CRB1,NPL,UBE2K,HSD17B4,WDR36,STARD4,JCHAIN,ZNF324B,IL6ST,CHPT1,LCP1,NUAK2,AXDND1,SKA3" MicroRNA hsa-miR-3176:mirSVR_lowEffct hsa-miR-3176:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.35E-21 3.37E-17 4.49E-20 4.11E-19 74 1811 "NLN,NYNRIN,TBC1D14,WDR35,HOMEZ,RGS5,PPFIA4,DDX55,NCOA1,MYH6,FGFRL1,BCL2L2,ARHGEF7,CCNA1,LINC02347,RILPL1,CD1D,XPR1,PIWIL1,AKAP6,FAM163A,GNPTAB,POU2F1,LYSMD3,SNCAIP,IL20,CMTM5,CTSG,EIF2AK2,ZNF586,DCAF8,MATR3,TSEN15,RNF31,ZNF329,TXNDC15,TRIM28,CWC27,PCGF3,ARL6IP4,TMEM156,TOMM40L,SDC1,PEAR1,GOLGA2P5,NUBPL,ARHGEF40,CCDC88A,UGGT2,PDS5B,RAPGEF6,NAAA,CD244,IKBIP,DHRS4,CNTN2,RNF17,ATP6V0A2,NPL,ADAMTS19,UBE2K,WDR36,NSD2,TADA2B,ZBED3-AS1,KCNN2,KIR2DL4,TTC41P,LINC01913,RMST,LMNB1,PABPN1,SKA3,MICU2" MicroRNA hsa-miR-376a:mirSVR_highEffct hsa-miR-376a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.06E-21 3.75E-17 4.98E-20 4.56E-19 58 1146 "MDM4,TMEM132B,APC,CDKL4,STARD13,AMDHD1,CD1D,UHMK1,PDGFRA,PGGT1B,GPR180,ITGBL1,NRXN1,LINC01085,CSNK1G3,LRRTM2,PRKD1,COG3,TBC1D4,OCIAD1,TINF2,DNMT3A,ATG10,EIF2B1,ZNF671,CWC27,ELOVL7,FGF9,POLK,SLC34A2,FBXO11,PAICS,GFM2,SCYL2,YPEL5,GABRA2,PDS5B,HSPH1,SRP72,GC,LPIN1,ZNF544,TMED2,GTF2H3,UBE2K,TXK,ZNF550,VRK2,KCNT2,ZNF84,ANKS1B,ZMYM2,FAM151B,ZBED3-AS1,SPRYD7,LIG4,IFT88,LOX" MicroRNA hsa-miR-1915*:mirSVR_lowEffct hsa-miR-1915*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.12E-21 3.79E-17 5.02E-20 4.60E-19 64 1386 "SEMA6A,MMP17,CUL4A,SNX24,NOP14,ASTN1,SLC4A4,KCTD12,BCL2L2,FCRL3,ARHGEF7,BTF3,AP1G2,CBLN3,CAD,MPZL1,UHMK1,RFLNA,RGSL1,PDE6B,SLC25A3,CFAP54,PTPRVP,THAP6,FAM163A,TAPT1,COPA,FAM53A,POU2F1,NGDN,NCOR2,NOS1AP,MATR3,PIGG,DNMT3A,FAM129A,OGFOD2,RGS12,CLIP4,MBNL2,PCGF3,F7,TOMM40L,FLT1,SLC34A2,SLC8A1,TMEM132D,MEGF10,PDS5B,JPH4,ATP8A2,MRPS27,PSME4,PPIP5K2,UBE2K,SLAIN1,WDR36,DCP2,IL6ST,PLB1,ZNF140,NPHS2,SPRYD7,SPATA13" MicroRNA hsa-miR-20a-5p:Functional MTI Functional MTI miRTarbase 7.58E-21 4.03E-17 5.34E-20 4.89E-19 56 1071 "ABL2,MCC,ADD1,ULK1,RGS5,ARL1,PPP1R12B,BCL2L2,ARHGEF7,FCHO2,CCNB1,CFL2,PFKFB2,GNPTAB,LYSMD3,CLOCK,NCOR2,BRI3BP,C12orf65,UBXN2A,MPHOSPH8,DCAF8,FBXL5,CEP120,OCIAD1,SACS,RABGAP1L,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,NTN4,ETF1,DNAJC27,N4BP2L2,SUCO,BRMS1L,ZNF446,GAK,ERAP1,KLHL20,ZBTB37,ADGRL3,GTF2H3,TXK,UBC,NSD2,TADA2B,TDRD3,KIT,ZDHHC20" MicroRNA hsa-miR-526b:mirSVR_highEffct hsa-miR-526b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.18E-21 4.35E-17 5.75E-20 5.27E-19 55 1035 "MAP1B,BLZF1,AACS,ODC1,LDB2,UHMK1,PAH,ZNF664,DCLK1,PCSK1,PDGFRA,GPR180,LTB4R,PTPRVP,THAP6,STRN3,POU2F1,CEP135,DNM3,UBXN2A,PRKD1,BIVM,PSME1,PIGG,CEP350,PTPRC,NR1H4,GUSBP3,MPHOSPH9,CWC27,CLIP1,TOMM40L,POLK,SUPT20H,VEZT,GFM2,IVNS1ABP,SLC12A2,NR5A2,PDS5B,UHRF1BP1L,IKBIP,MAST4,LINC02393,ACSL6,TCF7,RIPK3,MAEL,ADAMTS19,NLRP8,VRK2,IL6ST,SPTSSA,AXDND1,LMNB1" MicroRNA hsa-miR-219-1-3p:mirSVR_lowEffct hsa-miR-219-1-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.23E-21 4.38E-17 5.78E-20 5.29E-19 71 1687 "RALGAPA1,MAP1B,MDM4,ADD1,ACOX3,WDR35,RGS5,MSH2,ARHGAP5,SLC4A4,ZNF542P,KCTD12,BTF3,GLT1D1,PDE6B,ZNF595,PIGR,SNX6,THAP6,SNCAIP,LACC1,CEP135,EIF2AK2,NOS1AP,IFT172,SNX17,CEP350,NUDT12,OCIAD1,RABGAP1L,GNPDA2,RASA1,TMEM33,LRPPRC,PACRGL,EFNA5,ELF1,DHRS2,BORA,ARSK,ADGRV1,USP44,FCAR,PIBF1,FMO1,DDX51,PAICS,SCYL2,NMNAT2,ERBIN,TMED2,PPIP5K2,CNTN2,DOCK9,TFDP1,CRB1,ZBTB49,ATP6V0A2,NPL,GUF1,RXFP2,FCRL6,KCNT2,TADA2B,ZNF324B,ZBTB41,FAM151B,DNAH10,FAM71C,LMNB1,LTA4H" MicroRNA hsa-miR-548b-3p:mirSVR_highEffct hsa-miR-548b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.64E-21 4.60E-17 6.06E-20 5.55E-19 53 962 "ATP2B4,CDKL2,LDB2,CCNB1,UHMK1,CHD1,PFKFB2,ZNF595,PGGT1B,PIK3C2B,ATAD2B,BOD1L1,THAP6,HOMER1,AKAP6,ZFYVE16,MATR3,COG3,DCT,FBXL5,PXMP2,WDR1,NR1H4,TMEM161B,SMC6,CLIP4,RNASEL,LATS2,STX2,F7,NDUFAF7,N4BP2L2,PIBF1,POLK,FOXO1,NBEA,UFM1,MYT1L,CD244,HSPH1,NPAS3,MRPS27,KLHL20,COMMD6,GJB2,COX18,TFDP1,CRB1,RAB2B,TNR,GUF1,ZMYM2,SDR39U1" MicroRNA hsa-miR-3116:mirSVR_lowEffct hsa-miR-3116:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.83E-21 4.70E-17 6.19E-20 5.66E-19 72 1733 "MAP1B,ADD1,ADCY4,PPFIA4,FAM193A,ASTN1,CENPBD1P1,ZNF542P,CADM3,NFATC4,LINC02347,NOVA1,CACNA1E,ZNF664,PDE4D,CENPC,VIT,WDFY2,POLE,SNCAIP,CSNK1G3,CMTM5,NOS1AP,EPS8L1,CEP350,FAM129A,GUSBP3,PACRGL,RNF4,DCUN1D2,KLHL12,FAM81B,MAEA,PCGF3,SLC22A17,TNFRSF19,FOXG1,STAB2,RASA3,TM9SF1,SLC34A2,C1orf112,SLC22A5,FSHR,LIMCH1,DCAF11,MEGF10,PDS5B,KDM5B,GAK,ZNF274,GJB6,SULT1E1,PPIP5K2,CNTN2,ANO4,STON1,C1QTNF9B,NCSTN,LINC01551,AP4S1,RASSF6,HPCAL1,VRK2,MZF1,CCDC169,PLB1,KIR2DL4,KIR2DS4,LINC01913,LCP1,SKA3" MicroRNA hsa-miR-183:mirSVR_highEffct hsa-miR-183:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.04E-21 4.81E-17 6.32E-20 5.79E-19 50 855 "MDM4,BIRC6,MSH2,ASTN1,PNP,FCHO2,PCK2,PFKFB2,GPR180,HOMER1,ZFYVE16,PTGS2,DMXL1,SACS,PPP2R3C,TSEN15,FAM129A,RB1,LAP3,POLR1D,NTN4,LATS2,CWC27,CLIP1,GORAB,RELL1,SUCO,MROH9,BRMS1L,UFM1,POTEM,WDCP,YPEL5,NPAS3,NFASC,LRCH1,ERBIN,GJA3,PPIP5K2,EML4,ACTR6,TMPO,RIMBP2,SLAIN1,TENT2,ZMYM2,TMEM178A,KIF2A,ZDHHC20,LOX" MicroRNA hsa-miR-378c:mirSVR_highEffct hsa-miR-378c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-21 4.83E-17 6.35E-20 5.81E-19 54 1000 "HOMEZ,DDX55,BCL2L2,ARHGEF7,DAOA,NRL,CHAMP1,SLC5A8,PCCA,PCK2,CHIT1,ZNF595,GPR180,TM9SF2,PIK3C2B,ATAD2B,ADGRF3,TOGARAM2,DCAF8,TINF2,G3BP2,GNPDA2,RASA1,IPO4,RGS4,CLIP4,POLR1D,MBNL2,FCGR3A,LRRN2,FOXG1,MROH9,FLT1,VEZT,SLC34A2,MBIP,IVNS1ABP,PKD2L2,GABRB1,ERAP1,MRPS27,STRN,GZMB,FZD10,UBE2K,GPN1,ZNF876P,VRK2,IL6ST,FIP1L1,KIF2A,SLAMF9,NUAK2,SPRYD7" MicroRNA hsa-miR-1913:mirSVR_lowEffct hsa-miR-1913:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.41E-21 5.00E-17 6.57E-20 6.01E-19 72 1735 "NDRG2,ACOX3,ADORA1,SEMA6A,HOMEZ,APBB2,WDR19,CCDC181,CADM3,ATP7B,BCL2L2,NFATC4,CCNA1,CAD,LDB2,NFXL1,SCFD2,MRPL57,ATAD2B,PTPRVP,THAP6,C1orf116,STRN3,FAM53A,SNCAIP,ZFYVE16,G3BP2,DNMT3A,GALNT14,FAM129A,ZNF329,OGFOD2,AASDH,EFNA5,KIRREL1,ZNF219,EFS,STK32B,ABCA11P,USP44,TMEM129,SLC34A2,PLEKHA6,ZNF605,P2RX2,NR5A2,CHFR,EFR3B,DCAF11,KIF21B,PDS5B,NMNAT2,TMEM183A,NFASC,RBKS,LILRB1,IKBIP,KLHL20,GJB2,BRD8,MAST4,ANO4,RASSF6,NPL,KLF12,LTB4R2,NLRP8,ZNF470,PLB1,KIF3C,SPRYD7,PABPN1" MicroRNA hsa-miR-320c:mirSVR_highEffct hsa-miR-320c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.54E-21 5.07E-17 6.65E-20 6.09E-19 64 1394 "SFTA3,SMIM15,SEMA6A,WDR19,CACNA1E,LDB2,PCCA,PCDH9,ZMYM5,RGSL1,GLT1D1,RCBTB2,VIT,MRPL57,LINC01085,BOD1L1,THAP6,AKAP6,POU2F1,CLOCK,CEP135,SPATA18,SREK1,DMXL1,TBC1D4,CEP120,SUPT7L,WDR1,FAM129A,RASA1,LRPPRC,EIF2D,RNASEL,GRTP1,EIF2B1,ZNF671,EFS,ADGRV1,PCGF3,USP44,NDUFAF7,PIBF1,SUPT20H,VEZT,ZCCHC8,FBXO11,MBIP,C1orf112,LIMCH1,GABRB1,PDS5B,INSM2,ATP11A,PPIP5K2,METAP2,C5orf56,TDG,BAZ1A,MAEL,RXFP2,SPTSSA,ANKS1B,NPHS2,MFSD2B" MicroRNA hsa-miR-1276:mirSVR_highEffct hsa-miR-1276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.80E-21 5.21E-17 6.82E-20 6.25E-19 58 1154 "SEMA6A,CUL4A,FBRSL1,APC,DDX55,MYBPC1,ATP7B,ARHGEF7,BTF3,PNP,FCHO2,CD1E,PGGT1B,WDFY2,ITGBL1,SYCP3,CSNK1G3,VCAN,ZFYVE16,SPATA18,PIGG,SREK1,COCH,CEP120,G3BP2,NR1I3,FAM129A,ATG10,RB1,SMC6,RNF4,DLEU1,CLIP1,F7,USP44,TRAPPC13,GORAB,FOXO1,RASA3,THADA,GABRB1,KDM5B,ERAP1,PPARGC1A,STRN,PSME4,PPIP5K2,AP4S1,ARHGAP30,TXK,ZNF550,JCHAIN,CCDC190,CHPT1,KCNN2,TTC41P,AXDND1,LMNB1" MicroRNA hsa-miR-379:mirSVR_lowEffct hsa-miR-379:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-20 5.66E-17 7.40E-20 6.78E-19 52 930 "APAF1,APBB2,CDKL4,MSH2,ASCL1,ASTN1,SLC4A4,NFATC4,CAST,PDGFRA,CENPC,BOD1L1,UGT2B28,THAP6,AKAP6,MPC2,TTC37,FCRL5,EIF2AK2,GLT8D2,EPS8L1,PIGG,PTGS2,TBC1D4,G3BP2,DNMT3A,B3GLCT,RNF31,DCUN1D2,GP6,STK32B,DNAJC27,PCGF3,F7,VEZT,N4BP2,MEGF10,CMPK2,PPARGC1A,DHRS4,MAST4,PPIP5K2,MTUS2,ACSL6,ARHGEF28,TFDP1,RIMBP2,POC5,TADA2B,LHX9,KIF2A,PABPN1" MicroRNA hsa-miR-561:PITA hsa-miR-561:PITA_TOP PITA 1.14E-20 6.05E-17 7.90E-20 7.23E-19 53 968 "MATN3,BIRC6,APC,WDR19,ARHGAP5,ASCL1,SLC4A4,CAST,FCHO2,LDB2,NRXN1,ATAD2B,HECTD1,STRN3,MPC2,CRHBP,CSNK1G3,DNM3,CEP350,SACS,ARGLU1,RGS4,TMEM33,MBNL2,TBC1D19,USP44,FGF9,SDC1,NBEA,CCDC92,SCYL2,CCDC88A,SLC12A2,MEGF10,MYT1L,ERAP1,KDM3B,CMPK2,UTP20,CNTN2,ADGRL3,TCF7,EML4,KMT5A,MSH6,ATP6V0A2,UBE2K,POC5,NSD2,YTHDC2,IGF1,KCNN2,SPRYD7" MicroRNA hsa-miR-16:mirSVR_highEffct hsa-miR-16:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.16E-20 6.19E-17 8.06E-20 7.38E-19 65 1441 "RGS5,SLC4A4,ATP4B,MYBPC1,PPP1R12B,BCL2L2,NOVA1,CACNA1E,CAMK4,CAST,PCDH9,CDK17,GLT1D1,CFL2,GPR180,ITGBL1,CFAP54,CFAP45,JAKMIP1,THAP6,IL20,VCAN,LRRTM2,FCRL2,DCAF8,COCH,TMEM161B,DTD2,CLIP4,LATS2,MBNL2,TBC1D19,ABCA11P,FGF9,SUCO,FLT3,RUBCNL,IVNS1ABP,ARHGEF40,SLC15A4,SLC22A4,MYT1L,ERAP1,NPAS3,NFASC,LRCH1,PCDH17,INSM2,C5orf56,COP1,CRB1,FZD10,GPN1,HTR2A,DCP2,ZMYM2,LHX9,CHPT1,KIF2A,KIR2DS4,TTC41P,LINC01913,LCP1,RMST,SPRYD7" MicroRNA hsa-miR-203:PITA hsa-miR-203:PITA_TOP PITA 1.16E-20 6.19E-17 8.06E-20 7.38E-19 43 625 "RALGAPA1,SEMA6A,APC,ARHGAP5,SLC4A4,BCL2L2,NOVA1,CACNA1E,PDE4D,GPR180,CFAP45,HECTD1,HOMER1,AKAP6,FAM53A,CLOCK,LRRTM2,MATR3,MBNL2,FOXG1,NBEA,SLC30A6,SCYL2,IVNS1ABP,TADA1,SLC12A2,PDS5B,NMNAT2,PPARGC1A,PSME4,INSM2,TMED2,ATP11A,SCFD1,XPO4,GRSF1,UBE2K,TENT2,HTR2A,DCP2,YTHDC2,ZMYM2,KIF2A" MicroRNA hsa-miR-4259:mirSVR_lowEffct hsa-miR-4259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-20 6.20E-17 8.07E-20 7.39E-19 66 1483 "RALGAPA1,MAP1B,KIAA1211,SLAMF6,ATP6V1G3,ARHGAP5,NOP14,BCL2L2,CD84,NOVA1,CDKL2,CAST,AMDHD1,RILPL1,PDGFRA,CHD1,CKMT2,CPNE6,LINC01085,HOMER1,AKAP6,FAM163A,LYSMD3,LRRTM2,PRKD1,GLT8D2,OCIAD1,RABGAP1L,NR1I3,RGS12,RNF4,ELF1,MARVELD2,ABCA11P,POLK,FOXO1,STAB2,SLC34A2,CCDC92,SLC30A6,ARHGEF40,MRPS14,LIMCH1,CYP1B1-AS1,NAAA,ATP8A2,MCCC2,LRCH1,ZNF544,COX7B2,PPIP5K2,TEP1,CRB1,SLC7A8,AP4S1,RASSF6,ZNF721,UBE2K,ARHGAP30,GUF1,ZNF84,LHX9,TMEM178A,LOX,EEF1AKMT1,SKA3" MicroRNA hsa-miR-4327:mirSVR_lowEffct hsa-miR-4327:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-20 6.34E-17 8.23E-20 7.53E-19 59 1198 "ABL2,MDM4,NLN,FBRSL1,WDR19,SLC4A4,CDKL2,PCDH9,PDGFRA,SMIM14,PITX1,PTPRVP,THAP6,HOMER1,TAPT1,POU2F1,LYSMD3,VCAN,LRRTM2,FAM169A,KIAA0040,MPHOSPH8,NOS1AP,MATR3,PTPRC,FAM129A,RASA1,RGS12,PACRGL,DNAJC27,GMPR2,F10,NDUFAF7,N4BP2L2,STAB2,SGCG,ZNF605,SLC12A2,TMEM132D,IKBIP,KLHL20,MIMT1,ADGRA3,ANO4,TEP1,GRSF1,AP4S1,RASSF6,TNR,GPN1,GUF1,SLAIN1,YTHDC2,KCNT2,ZBED3-AS1,EP400P1,LCP1,ZDHHC20,SPATA13" MicroRNA hsa-miR-1284:mirSVR_highEffct hsa-miR-1284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-20 6.40E-17 8.30E-20 7.60E-19 58 1159 "MAP1B,ANKRD34B,MSH2,BLZF1,STARD13,CARMIL3,TAF1B,CHAMP1,FAM177A1,CENPC,ZNF595,NRXN1,BOD1L1,ADGRF3,HECTD1,HOMER1,STRN3,LYSMD3,VCAN,CEP135,PRKD1,FCRL2,GLT8D2,SPATA18,SREK1,CEP120,PARPBP,RASA1,TMEM161B,AASDH,FAM228A,RNASEL,SNORA53,MPHOSPH9,STX2,ADGRV1,TRAPPC13,RELL1,BRMS1L,UFM1,TADA1,GABRA2,PDS5B,ERAP1,ERBIN,PCDH17,SULT1E1,PPIP5K2,ANO4,ACSL6,ARHGEF28,ZBTB49,TENT2,IL25,SPTSSA,ZMYM2,ZBED3-AS1,KIT" MicroRNA hsa-miR-3126-5p:mirSVR_lowEffct hsa-miR-3126-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-20 6.45E-17 8.35E-20 7.65E-19 71 1699 "MDM4,BIRC6,ADD1,ADORA1,COG6,TBC1D14,AACS,ASTN1,B4GALT3,CARMIL3,BCL2L2,NEDD8,CAST,SCARB1,WDFY2,PIK3C2B,BOD1L1,THAP6,CLOCK,PREPL,VCAN,PRKD1,ZFYVE16,EPS8L1,SREK1,CEP120,GNPDA2,FAM129A,RNF31,RGS4,RNF4,MBNL2,KIRREL1,TBC1D19,MAEA,PCGF3,TNFRSF19,SDC1,FLT1,TM9SF1,IVNS1ABP,SLC15A4,C1orf112,CYP1B1-AS1,GABRB1,ZNF274,ERAP1,CMPK2,NFASC,DRC1,MCCC2,GJA3,MAST4,ADGRL3,C5orf56,DOCK9,COP1,XPO4,TFDP1,AP4S1,ARHGAP30,NLRP8,PAPPA2,ZNF470,CCDC169,PGAM5,KCNN2,KIF3C,LETM1,SPRYD7,AXDND1" MicroRNA hsa-miR-1236:mirSVR_highEffct hsa-miR-1236:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-20 6.66E-17 8.62E-20 7.89E-19 61 1279 "NDRG2,KIAA1211,SLAMF6,NCOA1,STARD13,PNP,DAOA,PDE4D,PDGFRA,PIGR,SMIM14,JAKMIP1,LACC1,FCRL5,GLT8D2,ZNF586,SNX17,SREK1,PPP2R3C,FAM129A,ARGLU1,TMEM161B,MBNL2,TRAPPC12,EIF2B1,ELF1,LGR6,FCAMR,DRAM1,MAEA,DLEU1,F10,TMEM156,UTP15,TOMM40L,FGFR3,SUCO,FBXO11,SCYL2,ZNF605,CGREF1,EAPP,NFASC,MCCC2,ZBTB37,UGT2A1,INSM2,METAP2,TCF7,RIPK3,ADAMTS19,GPN1,ARHGAP30,GUF1,PAPPA2,NSD2,FAM151B,TTC41P,LINC01913,RMST,AXDND1" MicroRNA hsa-miR-377*:mirSVR_lowEffct hsa-miR-377*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-20 7.12E-17 9.20E-20 8.42E-19 69 1615 "ABL2,WDR35,CUL4A,BLZF1,NOP14,AACS,ATP4B,CD84,BTF3,RAB29,RGSL1,PDE4D,GLT1D1,WDFY2,TM9SF2,ATAD2B,PTPRVP,LYSMD3,SNCAIP,C12orf65,CEP135,DNM3,GLT8D2,NUDT12,CEP120,OCIAD1,PPP2R3C,SMC6,MEMO1,EFNA5,RNF4,ELK3,LGR6,DHRS2,TCTN2,ZNF671,PCGF3,F10,ELOVL7,TMEM129,FOXG1,FLT1,STAB2,SUPT20H,VEZT,SGCG,DDX51,PLEKHA6,DCAF11,MEGF10,GABRA2,GABRB1,ADGRL3,ADGRA3,C5orf56,EML4,KHNYN,ZBTB49,ADAMTS19,TECRL,MZF1,PLB1,SPTSSA,ZMYM2,LHX9,KIF3C,DNAH10,LINC01913,LCP1" MicroRNA hsa-miR-3168:mirSVR_highEffct hsa-miR-3168:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-20 7.26E-17 9.37E-20 8.58E-19 53 972 "MIPEP,CDKL4,CDKL2,ZMYM5,VIT,SMIM14,JAKMIP1,TAPT1,PM20D1,THTPA,NGDN,FAM169A,DCAF8,PTPRC,TINF2,G3BP2,LINC01257,C14orf119,LAP3,RGS12,MEMO1,ELF1,ABCA11P,TRAPPC13,NDUFAF7,RELL1,FOXO1,FLT1,TM9SF1,BRMS1L,THADA,CGREF1,MEGF10,GABRB1,PDS5B,CMPK2,RBKS,MCCC2,PPARGC1A,ADGRL3,EML4,RNF17,NT5C1B,CRB1,TMPO,TECRL,HSD17B4,YTHDC2,JCHAIN,ZMYM2,KCNN2,KIR2DS4,IFT88" MicroRNA hsa-miR-3136:mirSVR_highEffct hsa-miR-3136:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-20 7.51E-17 9.68E-20 8.86E-19 60 1242 "MDM4,NLN,WDR35,NCOA1,PROZ,PCCA,PCDH9,CDK17,CFL2,CCDC122,WDFY2,GPR180,ITGBL1,LINC01085,ATAD2B,THAP6,AKAP6,PM20D1,VCAN,DNM3,UBXN2A,SNX17,G3BP2,WDR1,NR1I3,RASA1,RB1,MBNL2,TRAPPC12,FAM81B,ETF1,ABCA11P,N4BP2L2,RELL1,FLT1,N4BP2,LIMCH1,CYP1B1-AS1,PDS5B,NAAA,ERAP1,PCDH17,ZBTB37,PPARGC1A,ADGRA3,EML4,RNF212,RNF17,CRB1,GTF3C2,TMPO,ZNF721,NPL,TENT2,FCRL6,ZNF10,IL6ST,ZBTB41,LCP1,LMNB1" MicroRNA hsa-miR-101:mirSVR_highEffct hsa-miR-101:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-20 7.92E-17 1.02E-19 9.34E-19 63 1365 "MDM4,PPFIA4,APAF1,CDKL4,MSH2,ARHGAP5,ASCL1,KCTD12,NOVA1,CHAMP1,UHMK1,FAM177A1,CENPC,NRXN1,PIK3C2B,LYSMD3,CSNK1G3,CEP135,PTGS2,TBC1D4,RABGAP1L,SUPT7L,TSEN15,RNF219,DNMT3A,TMEM161B,FAM228A,DTD2,SLC9C2,ZNF419,EFNA5,TXNDC15,MPHOSPH9,SAP18,SH3YL1,FOXO1,SUPT20H,RUBCNL,UFM1,GFM2,CCDC88A,SLC12A2,TMEM132D,SLC15A4,MYO16,PDS5B,RAPGEF6,IQGAP2,KDM3B,NEDD1,ERBIN,PCDH17,TDG,ACTR6,RIMBP2,HEXB,TRPC4,HMGCR,PAPPA2,SELENOI,CCDC190,ZMYM2,LMNB1" MicroRNA hsa-miR-3129:mirSVR_highEffct hsa-miR-3129:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-20 8.14E-17 1.05E-19 9.58E-19 57 1126 "RALGAPA1,MDM4,ASTN1,KCTD12,NOVA1,CDKL2,DCLK1,CDK7,CDK17,PDGFRA,CENPC,CFL2,CFAP54,PIGR,GNPTAB,FCRL5,GLT8D2,DMXL1,TBC1D4,PTPRC,G3BP2,TSEN15,DNMT3A,FAM129A,RB1,TMEM161B,DTD2,RGS4,RNASEL,MARVELD2,FAM172A,CLIP1,SH3YL1,FCGR3A,FCGR3B,GORAB,RELL1,FOXO1,G2E3,BRMS1L,UFM1,TMEM132D,NPAS3,LRCH1,UTP20,EML4,RNF17,MAEL,GUF1,TENT2,KCNT2,ZMYM2,TMEM178A,KCNN2,KIF2A,IFT88,LOX" MicroRNA hsa-miR-128:mirSVR_highEffct hsa-miR-128:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.57E-20 8.32E-17 1.07E-19 9.78E-19 56 1088 "RALGAPA1,MDM4,CENPBD1P1,CD84,FCRL3,CAST,PAH,PCDH9,FAM177A1,CDK18,PDE4D,CEBPE,PGGT1B,LINC01085,HECTD1,EPGN,LACC1,VCAN,ITSN2,PRKD1,FCRL2,SREK1,RNF219,RB1,TMEM161B,ZNF329,TRAPPC12,SPATA9,FAM172A,F10,FCAR,NDUFAF7,SUCO,PAICS,CCDC88A,SLC22A4,GABRB1,KIF21B,NPAS3,SRP72,MCCC2,COMMD6,TBC1D1,PPIP5K2,CRB1,HTR2A,WDR36,JCHAIN,IL6ST,ZNF140,SDR39U1,ZBED3-AS1,KIR2DS4,LMNB1,IFT88,SKA3" MicroRNA hsa-miR-1238:mirSVR_lowEffct hsa-miR-1238:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-20 8.36E-17 1.07E-19 9.82E-19 55 1050 "SMIM15,WDR35,APBB2,NCOA1,NFATC4,CBLN3,SCFD2,PDE4D,COLEC11,SMIM14,JAKMIP1,POLN,THAP6,AKAP6,RNASE9,IL20,ZNF586,PARPBP,RGS12,CLIP4,SETDB2,MBNL2,EIF2B1,MPHOSPH9,STX2,FAM172A,F10,ARL6IP4,SFSWAP,RASA3,C1orf112,MRPS14,RAPGEF6,MIMT1,LPIN1,UGT2A1,SPIC,C5orf56,TCF7,TMPO,TNR,NPL,ADAMTS19,TRPC4,GPN1,VRK2,WDR36,ZNF10,IGF1,ZNF470,IL6ST,CCDC190,KCNN2,AXDND1,ZNF304" MicroRNA hsa-miR-520d-3p:mirSVR_highEffct hsa-miR-520d-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.60E-20 8.52E-17 1.09E-19 9.99E-19 63 1367 "MDM4,KIAA1211,CUL4A,B4GALT3,CCNA1,CACNA1E,MORN2,CD1E,FCRLB,RFLNA,PCDH9,FAM177A1,RGSL1,CFL2,PGGT1B,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,C12orf65,ITSN2,CEP135,NUDT12,TBC1D4,GNPDA2,IPO4,CLIP4,NTN4,RNASEL,LATS2,MPHOSPH9,DRAM1,DNAJC27,IRF9,FCGR2B,RELL1,PIBF1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,ARHGEF40,MYT1L,ZBTB37,INSM2,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,TEP1,NT5C1B,EMILIN1,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-15b:mirSVR_highEffct hsa-miR-15b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.84E-20 9.80E-17 1.25E-19 1.15E-18 65 1454 "RGS5,ATP4B,MYBPC1,BCL2L2,CACNA1E,CAMK4,CAST,PCDH9,CDK17,PDE4D,GLT1D1,CHD1,GPR180,ITGBL1,CFAP54,NRXN1,CFAP45,JAKMIP1,HECTD1,THAP6,PREPL,IL20,LRRTM2,FCRL2,DCAF8,COCH,G3BP2,TMEM161B,CLIP4,MBNL2,TBC1D19,ABCA11P,TMEM156,FGF9,SUCO,FLT3,BRMS1L,IVNS1ABP,ARHGEF40,SLC15A4,SLC22A4,YPEL5,MYT1L,ERAP1,NPAS3,NFASC,LRCH1,PCDH17,INSM2,KMT5A,RNF212,COP1,FZD10,NPL,GPN1,HTR2A,ANKS1B,ZMYM2,CHPT1,KIF2A,KIR2DS4,LINC01913,LCP1,RMST,SPRYD7" MicroRNA hsa-miR-1323:PITA hsa-miR-1323:PITA_TOP PITA 1.86E-20 9.88E-17 1.26E-19 1.15E-18 44 665 "SMIM15,NLN,SEMA6A,ASCL1,SLC4A4,PPP1R12B,NOVA1,ODC1,FCHO2,NFXL1,PCSK1,ATAD2B,STRN3,TAPT1,LYSMD3,CLOCK,CSNK1G3,BIVM,SREK1,COG3,RASA1,SMC6,MEMO1,CLIP1,FNIP1,TNFRSF19,FGFR3,FBXO11,ALKAL2,MYT1L,PDS5B,PCDH17,PPARGC1A,STRN,KMT5A,BAZ1A,UBE2K,HMGCR,NSD2,SPTSSA,ZMYM2,ZBTB41,KIT,LMNB1" MicroRNA hsa-miR-548o:PITA hsa-miR-548o:PITA_TOP PITA 1.86E-20 9.88E-17 1.26E-19 1.15E-18 44 665 "SMIM15,NLN,SEMA6A,ASCL1,SLC4A4,PPP1R12B,NOVA1,ODC1,FCHO2,NFXL1,PCSK1,ATAD2B,STRN3,TAPT1,LYSMD3,CLOCK,CSNK1G3,BIVM,SREK1,COG3,RASA1,SMC6,MEMO1,CLIP1,FNIP1,TNFRSF19,FGFR3,FBXO11,ALKAL2,MYT1L,PDS5B,PCDH17,PPARGC1A,STRN,KMT5A,BAZ1A,UBE2K,HMGCR,NSD2,SPTSSA,ZMYM2,ZBTB41,KIT,LMNB1" MicroRNA hsa-miR-23a*:mirSVR_lowEffct hsa-miR-23a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.93E-20 1.03E-16 1.31E-19 1.20E-18 56 1093 "LRRC43,HOMEZ,PPFIA4,AACS,ASTN1,SLC4A4,CADM3,RAB29,FCRLB,RGSL1,CFL2,JAKMIP1,C1orf116,STRN3,POLE,TOGARAM2,NGDN,KIAA0040,DMXL1,PTPRH,MTX3,DHFR,SUPT7L,TSEN15,CLIP4,CRYL1,LRPPRC,PACRGL,KLHL12,LGR6,ABCA11P,TMEM156,UTP15,TOMM40L,TNFRSF19,CCDC88A,P2RX2,C1orf112,MEGF10,RAPGEF6,LRCH1,ATP11A,PPIP5K2,RNF17,GRSF1,LINC01551,IGSF8,HGFAC,TXK,VRK2,GALP,KCNN2,CAB39L,SLAMF9,LINC01913,LMNB1" MicroRNA hsa-miR-29b:mirSVR_lowEffct hsa-miR-29b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-20 1.07E-16 1.36E-19 1.24E-18 72 1759 "MCC,NDRG2,BIRC6,KIAA1211,CUL4A,MCFD2,MSH2,ARHGAP5,AACS,ATP2B4,LINC02347,ADGRD1,CACNA1E,DCLK1,CDK18,CFL2,LINC01085,PTPRVP,STRN3,TAPT1,NCOR2,LACC1,DNM3,PIGG,DMXL1,REST,TMEM33,SETDB2,LRPPRC,SNORA53,KIRREL1,LGR6,DHRS2,ARSK,STK32B,ABCA11P,PCGF3,F7,PCBD2,NDUFAF7,RELL1,SELP,VEZT,BRMS1L,SCYL2,EFR3B,MEGF10,ERAP1,ERBIN,PCDH17,PPARGC1A,MAST4,ATP11A,ADAM17,GPR12,XPO4,GPR161,FZD10,UBE2K,TXK,WDR36,NSD2,YTHDC2,TADA2B,ZNF324B,CCDC169,PLB1,ZBTB41,LMLN,KIR2DL4,KIR2DS4,LMNB1" MicroRNA hsa-miR-218-2*:mirSVR_highEffct hsa-miR-218-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-20 1.07E-16 1.37E-19 1.25E-18 48 801 "MDM4,NLN,STXBP6,CADM3,CACNA1E,CAST,PAH,PCCA,RGSL1,PGGT1B,ATAD2B,THAP6,NGDN,SNCAIP,VCAN,MATR3,SREK1,PTGS2,C12orf42,RB1,ZNF329,PACRGL,RNASEL,ARSK,ETF1,TMEM156,UTP15,MROH9,VEZT,ZNF605,OXGR1,IKBIP,COMMD6,MAST4,RNF17,TFDP1,UBE2K,HTR2A,ZNF26,IL6ST,SPTSSA,ZMYM2,FAM151B,CAB39L,KIF2A,RPGRIP1,IFT88,SKA3" MicroRNA hsa-miR-130b*:mirSVR_highEffct hsa-miR-130b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-20 1.20E-16 1.52E-19 1.39E-18 66 1502 "SFTA3,MDM4,HOMEZ,MCFD2,DDX55,ASCL1,LINC02347,RAB29,NOVA1,CAST,FCHO2,PCDH9,ZMYM5,RGSL1,PDGFRA,CHD1,TSTD1,NRXN1,PIGR,AKAP6,NGDN,SNCAIP,LACC1,ITSN2,BIVM,SREK1,PTPRC,RABGAP1L,RNF219,PACRGL,LATS2,PCOTH,CWC27,ETF1,ABCA11P,PCBD2,IRF9,TOMM40L,RELL1,FLT1,FTLP10,FBXO11,G2E3,ARHGEF40,SLC22A5,LIMCH1,GABRB1,JPH4,ATP8A2,NPAS3,IKBIP,METAP2,ANO4,NCSTN,TEP1,RAB2B,ZNF721,NPL,GUF1,FAM151B,ZBED3-AS1,KCNN2,FIP1L1,SPRYD7,AXDND1,CDK2AP1" MicroRNA hsa-miR-323b-5p:mirSVR_lowEffct hsa-miR-323b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-20 1.22E-16 1.54E-19 1.41E-18 56 1097 "MATN3,ACOX3,KIAA1211,KCTD12,BTF3,CCNA1,LINC02347,PCDH9,CDK7,CCDC122,THAP6,AKAP6,STRN3,PM20D1,CLOCK,LACC1,C12orf65,EIF2AK2,SACS,MTX3,C14orf119,DNMT3A,GUSBP3,LGR6,DHRS2,CWC27,PCBD2,RELL1,SELP,SUPT20H,GOLGA2P5,ZCCHC8,NUBPL,PKD2L2,C1orf112,UGGT2,MYT1L,PDS5B,CD244,IQGAP2,ERAP1,NFASC,RBKS,BRD8,CRB1,MSH6,TMPO,FZD10,TMEM174,SLAIN1,ZFHX2,CCDC169,ZBED3-AS1,KCNJ9,KIF3C,TTC41P" MicroRNA hsa-miR-4316:mirSVR_lowEffct hsa-miR-4316:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-20 1.23E-16 1.55E-19 1.42E-18 63 1377 "ADD1,KIAA1211,SLAMF6,NYNRIN,CUL4A,PPFIA4,ATP1A2,NFATC4,ARHGEF7,AP1G2,LINC02347,NFXL1,CDK17,CDK18,GLT1D1,CFL2,WDFY2,PIGR,PKP1,POLE,GNPTAB,VCAN,C12orf65,FCRL5,COG3,NUDT12,PTPRC,C12orf42,NR1H4,ATG10,POLR1D,EFNA5,DRAM1,ETF1,CLIP1,ELOVL7,TMEM129,TOMM40L,PEAR1,SCYL2,TMEM132D,CGREF1,C1orf112,ERBIN,KLHL20,NPFFR2,MAST4,ADGRL3,GTF2H3,TMPO,TPO,PAPPA2,VRK2,HTR2A,PLB1,ZMYM2,FIP1L1,KIR2DL4,KIR2DS4,EP400P1,TTC41P,LCP1,ZNF304" MicroRNA hsa-miR-494:PITA hsa-miR-494:PITA_TOP PITA 2.38E-20 1.27E-16 1.60E-19 1.47E-18 41 574 "MCC,CUL4A,ARHGAP5,SLC4A4,ARHGEF7,NOVA1,CAST,NFXL1,PCSK1,PDGFRA,CHD1,ATAD2B,CLOCK,TBC1D4,CEP120,F11R,G3BP2,RB1,TMEM161B,LATS2,MBNL2,ELF1,SAP18,SDC1,FOXO1,SFSWAP,RASA3,ZCCHC8,FBXO11,NBEA,BRMS1L,PDS5B,NMNAT2,ATP8A2,SRP54,PPARGC1A,TMED2,UBE2K,DCP2,ZBTB41,KIT" MicroRNA hsa-miR-2114:mirSVR_lowEffct hsa-miR-2114:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.39E-20 1.27E-16 1.61E-19 1.47E-18 63 1378 "KIAA1211,SEMA6A,ASTN1,B4GALT3,CARMIL3,PPP1R12B,FGFRL1,LINC02347,NOVA1,SCARB1,RCBTB2,PIK3C2B,GNPTAB,LACC1,LRRTM2,MPHOSPH8,DDX59,CEP350,KLHL3,WDR1,DNMT3A,SMC6,NTN4,RNASEL,EFNA5,RNF4,GP6,ADGRV1,FCAR,FCGR3A,FCGR3B,LRRN2,PAICS,UFM1,ZNF605,SLC12A2,C1orf112,KIF21B,ZNF274,ERAP1,GJB6,MRPS27,MCCC2,MTUS2,C5orf56,GPR12,ARHGEF28,TEP1,NT5C1B,CRB1,ADAMTS19,GUF1,SLAIN1,PAPPA2,NSD2,ZNF10,CCDC190,ANKS1B,LCP1,AXDND1,LMNB1,LOX,ZNF304" MicroRNA hsa-miR-302a:mirSVR_highEffct hsa-miR-302a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.80E-20 1.49E-16 1.88E-19 1.72E-18 65 1466 "MDM4,KIAA1211,CUL4A,B4GALT3,ARHGEF7,CCNA1,CACNA1E,FCRLB,RFLNA,ZNF664,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,JAKMIP1,THAP6,LYSMD3,CRHBP,SNCAIP,C12orf65,ITSN2,CEP135,SPATA18,DMXL1,RABGAP1L,GNPDA2,PARPBP,CLIP4,NTN4,RNASEL,LATS2,SNORA53,MPHOSPH9,STX2,DRAM1,DNAJC27,IRF9,FCGR2B,RELL1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,ARHGEF40,YPEL5,MYT1L,CENPJ,ZBTB37,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,TDG,EMILIN1,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-605:mirSVR_highEffct hsa-miR-605:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-20 1.56E-16 1.96E-19 1.80E-18 56 1103 "MAP1B,NLN,WDR35,SLC4A4,B4GALT3,ARHGEF7,CAST,ODC1,LDB2,ZNF664,PDGFRA,PIWIL1,MRPL57,BOD1L1,THAP6,FAM53A,CLOCK,CSNK1G3,CEP135,UBXN2A,FCRL5,ZNF586,PARPBP,RB1,MBNL2,DRAM1,USP44,FGF9,VEZT,SLC34A2,CCDC88A,SLC12A2,C1orf112,SNRPF,MYT1L,KDM5B,NAAA,MRPS27,KDM3B,CMPK2,NEDD1,LRCH1,KLHL20,PCDH17,MAST4,ADGRL3,NCSTN,TFDP1,MAEL,ADAMTS19,CHPT1,TMEM178A,CAB39L,RMST,CDK2AP1,PABPN1" MicroRNA hsa-miR-924:mirSVR_lowEffct hsa-miR-924:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.95E-20 1.57E-16 1.98E-19 1.81E-18 71 1727 "RALGAPA1,ABL2,IL17D,MDM4,BIRC6,APC,CD84,NFATC4,LINC02347,NOVA1,PNP,SNTG2,RGSL1,DHRS1,ZNF595,JAKMIP1,THAP6,HOMER1,C1orf116,COPA,LYSMD3,NCOR2,VCAN,DNM3,UBXN2A,FCRL5,CEP120,PTPRC,DHFR,NR1H4,FAM129A,ATG10,IPO4,RGS4,ELF1,USP44,TNFRSF19,SUPT20H,VEZT,G2E3,SLC30A6,IVNS1ABP,ARHGEF40,TADA1,ZNF667,UGGT2,UHRF1BP1L,ERAP1,NFASC,PPARGC1A,PPIP5K2,RNF17,GTF2H3,ACTR6,HEXB,GPN1,ZNF876P,NLRP8,PAPPA2,IGF1,KCNT2,SPTSSA,LHX9,LMLN,KCNN2,ANKDD1B,FIP1L1,KIF3C,EP400P1,LAD1,LTA4H" MicroRNA hsa-miR-142-5p:TargetScan hsa-miR-142-5p TargetScan 3.11E-20 1.65E-16 2.08E-19 1.90E-18 44 674 "CUL4A,FBRSL1,ASCL1,ATP2B4,KCTD12,CADM3,CAST,FCHO2,LDB2,CDK17,PDGFRA,NUP37,BOD1L1,CLOCK,COG3,SACS,MTX3,EGLN3,REST,EFNA5,PCGF3,IRF9,FNIP1,NBEA,CCDC92,ARHGEF40,ACIN1,MYT1L,PDS5B,LRCH1,PPIP5K2,NT5C1B,GRSF1,MSH6,GTF3C2,PAPPA2,HTR2A,IGF1,IL6ST,LHX9,FIP1L1,DIAPH3,KIT,NT5C1B-RDH14" MicroRNA hsa-miR-2278:mirSVR_highEffct hsa-miR-2278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.40E-20 1.81E-16 2.27E-19 2.08E-18 54 1030 "KIAA1211,HOMEZ,CUL4A,EP400,APC,NCOA1,MYH6,PPP1R12B,SLC5A8,PDGFRA,PGGT1B,ITGBL1,NRXN1,LINC01085,BOD1L1,HOMER1,PMCH,SNCAIP,IL20,FAM169A,PIGG,NUDT12,PXMP2,WDR1,EGLN3,ZNF419,RNF4,CWC27,ABCA11P,TRAPPC13,POLK,SLC15A4,C1orf112,NFASC,SRP72,DRC1,LPIN1,UTP20,METAP2,CNTN2,ADGRL3,TCF7,COP1,TNR,GUF1,SLAIN1,TENT2,STARD4,CCDC190,CHPT1,KIT,TTC41P,NUAK2,LOX" MicroRNA hsa-miR-592:mirSVR_highEffct hsa-miR-592:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-20 1.84E-16 2.31E-19 2.11E-18 56 1107 "TMEM132B,SNX24,ARL1,CENPBD1P1,ARHGEF7,NOVA1,TAF1B,PCDH9,PDE4D,PDE6B,GPR180,TSTD1,SNX6,BOD1L1,HOMER1,AKAP6,EPGN,FCRL5,ZNF586,SREK1,G3BP2,RABGAP1L,RNF31,FAM228A,CLIP4,MEMO1,EFNA5,UGT2A3,KLHL12,CLIP1,ELOVL7,FTLP10,SLC8A1,SLC12A2,KDM3B,GJB2,UGT2A1,TMED2,ADGRL3,ANO4,ACSL6,C1QTNF9B,ADAMTS19,YTHDC2,KCNT2,ZFHX2,IL6ST,PLB1,ANKS1B,IRF1,FIP1L1,DIAPH3,NUAK2,AXDND1,IFT88,SPATA13" MicroRNA hsa-miR-105:PITA hsa-miR-105:PITA_TOP PITA 3.61E-20 1.92E-16 2.40E-19 2.20E-18 36 433 "RALGAPA1,MAP1B,MCC,EP400,NCOA1,CADM3,ODC1,LDB2,PCCA,PCDH9,PDE4D,CFL2,TM9SF2,NRXN1,ATAD2B,NCOR2,CSNK1G3,DNM3,PRKD1,MBNL2,ETF1,CLIP1,NBEA,PLEKHA6,CCDC88A,SLC12A2,SRP54,PPIP5K2,RIMBP2,MAEL,KLF12,UBE2K,HTR2A,IGF1,SPTSSA,CDK2AP1" MicroRNA hsa-miR-340-5p:TargetScan hsa-miR-340-5p TargetScan 3.66E-20 1.95E-16 2.43E-19 2.23E-18 53 994 "MATN3,MCC,CUL4A,FBRSL1,MSH2,NCOA1,ATP12A,ATP2B4,CADM3,PPP1R12B,BCL2L2,CAST,LDB2,PCSK1,PDGFRA,CFL2,BOD1L1,COG3,KLHL3,DNMT3A,REST,RGS4,CLIP4,MEMO1,SBNO1,ELK3,DNAJC27,PCGF3,IRF9,FNIP1,G2E3,BRMS1L,ARHGEF40,N4BP2,ACIN1,GABRB1,PDS5B,IQGAP2,HSPH1,ATP11A,ADAM17,PPIP5K2,MTUS2,NT5C1B,GPR161,GTF3C2,PAPPA2,IGF1,IL6ST,IRF1,KIF2A,KIT,NT5C1B-RDH14" MicroRNA hsa-miR-218-5p:TargetScan hsa-miR-218-5p TargetScan 3.86E-20 2.05E-16 2.56E-19 2.35E-18 47 779 "ABL2,MCC,BIRC6,FBRSL1,ARHGAP5,FCHO2,PCDH9,PDGFRA,NRXN1,POU2F1,LYSMD3,KIAA0040,BIVM,RABGAP1L,RNF219,DNMT3A,EGLN3,MEMO1,MBNL2,DNAJC27,NBEA,CCDC88A,CHFR,MYO16,MYT1L,KIF21B,KDM3B,LRCH1,PCDH17,PPARGC1A,PSME4,ACSL6,DOCK9,KHNYN,GSX2,GPR161,RIMBP2,KLF12,DCP2,ANKS1B,LHX9,LMLN,CAB39L,KIF2A,KIF3C,KIT,LMNB1" MicroRNA hsa-miR-944:PITA hsa-miR-944:PITA_TOP PITA 3.86E-20 2.05E-16 2.56E-19 2.35E-18 52 958 "RALGAPA1,MATN3,MIPEP,SEMA6A,APBB2,APC,ARHGAP5,NCOA1,ASTN1,STARD13,BCL2L2,NOVA1,SCARB1,SLC5A8,DCLK1,CFL2,GPR180,ATAD2B,BOD1L1,THAP6,HOMER1,AKAP6,LYSMD3,LRRTM2,CEP135,ZFYVE16,COG3,WDR1,NTN4,RNF4,MBNL2,CLIP1,CCDC88A,SLC12A2,MEGF10,KDM5B,ERAP1,NPAS3,ERBIN,PCDH17,PPARGC1A,GJB2,XPO4,ATP6V0A2,ADAMTS19,KLF12,UBE2K,ZNF10,KCNT2,ZBTB41,LHX9,SPRYD7" MicroRNA hsa-miR-3153:mirSVR_highEffct hsa-miR-3153:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.96E-20 2.11E-16 2.62E-19 2.40E-18 63 1392 "EP400,BLZF1,ATP1A2,MYH6,PROZ,NOVA1,PNP,AMDHD1,CD1E,PCSK1,RGSL1,CHD1,CCDC122,WDFY2,CKMT2,TM9SF2,EPN1,RNASE9,TOGARAM2,ITSN2,DNM3,FCRL5,BIVM,WDR1,FAM129A,RB1,SETDB2,GUSBP3,EFNA5,KLHL12,BORA,DLEU1,TLR6,FGF9,SDC1,MROH9,FMO1,ARHGEF40,SLC15A4,ACIN1,LIMCH1,MEGF10,GABRA2,GABRB1,JPH4,NPAS3,NEDD1,PPARGC1A,ZNF544,TBC1D1,INSM2,TMED2,PPIP5K2,RNF212,TNR,HEXB,SLAIN1,NLRP8,ZNF84,SDR39U1,AXDND1,PABPN1,LOX" MicroRNA hsa-miR-29c:mirSVR_lowEffct hsa-miR-29c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.47E-20 2.38E-16 2.96E-19 2.71E-18 69 1652 "MCC,NDRG2,BIRC6,KIAA1211,SEMA6A,CUL4A,MCFD2,MSH2,ARHGAP5,AACS,ATP2B4,LINC02347,ADGRD1,CACNA1E,DCLK1,CDK18,CFL2,LINC01085,PTPRVP,STRN3,FAM163A,TAPT1,NCOR2,LACC1,DNM3,PIGG,DMXL1,TMEM33,SETDB2,SNORA53,KIRREL1,LGR6,DHRS2,ARSK,STK32B,ABCA11P,PCGF3,PCBD2,NDUFAF7,SELP,BRMS1L,SCYL2,C1orf112,EFR3B,ERAP1,ERBIN,PCDH17,PPARGC1A,MAST4,ATP11A,ADAM17,STON1,XPO4,GPR161,FZD10,UBE2K,TXK,WDR36,NSD2,YTHDC2,TADA2B,ZNF324B,CCDC169,PLB1,ZBTB41,LMLN,KIR2DL4,KIR2DS4,LMNB1" MicroRNA hsa-miR-3132:mirSVR_lowEffct hsa-miR-3132:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.50E-20 2.40E-16 2.98E-19 2.72E-18 61 1313 "NDRG2,ADD1,WDR35,MCFD2,UVSSA,APAF1,MSH2,KCTD12,CADM3,NFATC4,ARHGEF7,BTF3,RAB29,NOVA1,MORN2,CDK18,RGSL1,CCDC122,GPR180,CPNE6,PIK3C2B,HECTD1,THAP6,AKAP6,MPC2,TAPT1,LRRTM2,KIAA0040,UBXN2A,EIF2AK2,SPATA18,PIGG,KLHL3,NUDT12,TBC1D4,OCIAD1,SUPT7L,PARPBP,RASA1,LGR6,MZB1,STK32B,CLIP1,F7,SUCO,STAB2,ZCCHC8,SLC22A4,PDS5B,MRPS27,KDM3B,CMPK2,LILRB1,KLHL20,CFHR4,TCF7,FZD10,NPL,UBE2K,GPN1,KIF3C" MicroRNA hsa-miR-202*:mirSVR_lowEffct hsa-miR-202*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.73E-20 2.52E-16 3.12E-19 2.86E-18 63 1397 "SLAMF6,WDR35,RGS5,UVSSA,APC,MSH2,ZNF784,ATP12A,SLC4A4,RAB29,DAOA,CD1D,ZNF664,FAM177A1,PCSK1,CENPC,GPR180,BOD1L1,C1orf116,STRN3,THTPA,LACC1,FCRL5,CEP350,NUDT12,OCIAD1,LINC01257,PARPBP,RASA1,ZNF329,LRPPRC,TXNDC15,ELF1,TBC1D19,FTLP10,UFM1,SLC12A2,YPEL5,NMNAT2,NEDD1,LPIN1,PPARGC1A,GJA3,MAST4,TBC1D1,PPIP5K2,ANO4,DOCK9,TEP1,GTF3C2,UBE2K,GPN1,GUF1,ZNF876P,PAPPA2,NSD2,JCHAIN,ZNF470,ZNF84,EP400P1,LINC01913,LIG4,ZNF304" MicroRNA hsa-miR-555:mirSVR_lowEffct hsa-miR-555:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.78E-20 2.54E-16 3.15E-19 2.89E-18 57 1154 "MDM4,COG6,UVSSA,KCTD12,CADM3,FCRL3,NOVA1,PCDH9,PCSK1,CDK17,PDGFRA,PFKFB2,COLEC11,THAP6,HEATR5A,CLOCK,SPATA18,SREK1,COG3,RABGAP1L,GNPDA2,SUPT7L,C14orf119,NR1H4,RASA1,TMEM33,RNF4,ARSK,TRAPPC13,FCGR3B,SPON2,TACC3,BRMS1L,NUBPL,CCDC88A,YPEL5,PDS5B,EAPP,TMEM183A,ZNF274,ANKLE2,GJB2,PSME4,ANO4,TCF7,DOCK9,RNF212,LHX9,TMEM178A,KCNN2,TTC41P,LAD1,LETM1,RMST,ZDHHC20,CDK2AP1,LOX" MicroRNA hsa-miR-182-5p:TargetScan hsa-miR-182-5p TargetScan 4.84E-20 2.57E-16 3.18E-19 2.92E-18 52 963 "ABL2,MAP1B,KIAA1211,RGS5,MCFD2,ASTN1,PPP1R12B,CHAMP1,CDK18,PDE4D,PDGFRA,NUP37,ATAD2B,BOD1L1,POU2F1,CLOCK,PREPL,PRKD1,EIF2AK2,COG3,DMXL1,NOP9,PARPBP,RASA1,DTD2,NTN4,EFNA5,RNF4,MBNL2,ETF1,DLEU1,PCGF3,FGF9,SDC1,FOXO1,CCDC92,BRMS1L,IVNS1ABP,CCDC88A,LIMCH1,MYT1L,GABRB1,RAPGEF6,ATP8A2,NFASC,GJA3,PSME4,DOCK9,RIMBP2,DCP2,C12orf73,FAM151B" MicroRNA hsa-miR-1293:mirSVR_lowEffct hsa-miR-1293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-20 2.70E-16 3.34E-19 3.06E-18 63 1399 "UVSSA,BLZF1,FAM193A,NCOA1,ATP2B4,FCHO2,PDGFRA,CCDC122,ZNF595,ITGBL1,LTB4R,POLE,IFT172,SLC35F6,PARPBP,TSEN15,TMEM161B,RGS12,MEMO1,POLR1D,MARVELD2,EFS,SLC22A17,FCAR,GORAB,POLK,SUCO,FTLP10,STAB2,GOLGA2P5,SLC8A1,PKD2L2,C1orf112,SF3B6,EFR3B,ACIN1,CYP1B1-AS1,ATP8A2,NFASC,LPIN1,PPARGC1A,BRD8,MAST4,INSM2,MTUS2,ARHGEF28,TDG,TFDP1,RIMBP2,ADAMTS19,TECRL,TXK,GUF1,TMEM174,WDR36,YTHDC2,ZNF140,ZMYM2,PGAM5,LHX9,ZBED3-AS1,FIP1L1,TTC7A" MicroRNA hsa-miR-512-3p:mirSVR_highEffct hsa-miR-512-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.25E-20 2.79E-16 3.45E-19 3.16E-18 47 785 "ABL2,KIAA1211,APC,B4GALT3,NFATC4,PCCA,RGSL1,RCBTB2,ZNF595,CFAP54,FAM163A,EPGN,CRHBP,LACC1,ZNF586,ZFYVE16,SREK1,RASA1,RNASE2,TXNDC15,MBNL2,KLHL12,TNFRSF19,PIBF1,POLK,SUCO,FMO1,IVNS1ABP,YPEL5,MYT1L,ERAP1,ZBTB37,PPARGC1A,MAST4,TMED2,ADAM17,TDG,RNF17,CRB1,HAL,NPL,HEXB,TECRL,PAPPA2,VRK2,HTR2A,ANKS1B" MicroRNA hsa-miR-581:mirSVR_highEffct hsa-miR-581:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.66E-20 3.01E-16 3.71E-19 3.40E-18 50 893 "WDR35,EP400,PNP,RILPL1,FCGR2C,PAH,PCDH9,PIWIL1,VIT,ITGBL1,ADGRF3,THAP6,DCAF8,RABGAP1L,PARPBP,DNMT3A,SETDB2,CWC27,ABCA11P,FCAR,TNFRSF19,PIBF1,SELP,FOXO1,FTLP10,SUPT20H,VEZT,FBXO11,ALKAL2,STPG4,ZNF605,WDCP,CYP1B1-AS1,MYT1L,FAM114A1,UHRF1BP1L,CMPK2,LILRB1,PCDH17,MIMT1,STRN,BRD8,MTUS2,ADAMTS19,ZNF876P,ZNF10,ZNF470,KCNN2,CAB39L,AXDND1" MicroRNA hsa-miR-562:mirSVR_highEffct hsa-miR-562:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.81E-20 3.09E-16 3.81E-19 3.49E-18 47 787 "MCC,FAM193A,CCNB1IP1,ARHGEF7,FAM177A1,XPR1,CFL2,CHD1,NRXN1,HECTD1,TAPT1,HEATR5A,C12orf65,MATR3,BIVM,SPATA18,PIGG,SUPT7L,PARPBP,EGLN3,RNF31,NTN4,EIF2B1,DEPDC4,ABCA11P,GORAB,FGF9,POLK,FOXO1,UFM1,GFM2,IVNS1ABP,SLC12A2,SNRPF,MYO16,KIF21B,NAAA,PPARGC1A,BRD8,INSM2,PPIP5K2,MAEL,ZNF721,ZMYM2,DIAPH3,LIG4,LTA4H" MicroRNA hsa-miR-4260:mirSVR_lowEffct hsa-miR-4260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.06E-20 3.22E-16 3.96E-19 3.63E-18 64 1446 "SFTA3,TMEM132B,RGS5,ARL1,FAM193A,CD84,FCRL3,NOVA1,TAF1B,FCGR2C,CDK17,CENPC,HECTD1,PTPRVP,THAP6,HOMER1,EPGN,LYSMD3,CEP135,DNM3,EIF2AK2,PSME1,CEP350,NUDT12,G3BP2,DHFR,LINC01257,PARPBP,AASDH,RGS12,CLIP4,ELK3,LGR6,TBC1D19,USP44,NDUFAF7,TNFRSF19,TACC3,SUCO,FOXO1,HSD17B7,STAB2,IVNS1ABP,CGREF1,PDS5B,ZNF274,MAST4,TBC1D1,TMED2,ADGRA3,RIPK3,STON1,KMT5A,NCSTN,TFDP1,CRB1,AP4S1,HEXB,GUF1,TMEM174,STARD4,IGF1,IL6ST,LMLN" MicroRNA hsa-miR-4297:mirSVR_lowEffct hsa-miR-4297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.21E-20 3.30E-16 4.06E-19 3.72E-18 67 1575 "TMEM132B,ACOX3,KIAA1211,CUL4A,PPFIA4,DDX55,CENPBD1P1,KCTD12,BTF3,CACNA1E,CDKL2,LDB2,CDK17,CFL2,CHD1,PFKFB2,THAP6,MPC2,HEATR5A,PREPL,SNCAIP,RGS12,TXNDC15,ELF1,ZNF219,EFS,MAEA,DNAJC27,SLC22A17,F10,HSD17B7,RASA3,TM9SF1,FBXO11,UFM1,SLC8A1,TADA1,POTEM,UGGT2,PDS5B,NMNAT2,RAPGEF6,SRP54,NFASC,GJA3,PPIP5K2,CNTN2,RIPK3,KHNYN,RNF212,SLC7A8,ZBTB49,LINC01551,TPO,PAPPA2,HTR2A,YTHDC2,ZNF470,PLB1,GALP,LHX9,CHPT1,KCNJ9,KIT,LINC00442,SPATA13,ZNF304" MicroRNA hsa-miR-935:mirSVR_highEffct hsa-miR-935:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.51E-20 3.46E-16 4.25E-19 3.89E-18 50 896 "RALGAPA1,HOMEZ,APAF1,APC,MSH2,FCRLB,PCDH9,CENPC,CFL2,RCBTB2,PGGT1B,GPR180,SMIM14,HOMER1,PMCH,MPC2,LYSMD3,CSNK1G3,SPATA18,FAM228A,LATS2,MBNL2,ADGRV1,FCGR2B,MROH9,FOXO1,RUBCNL,FBXO11,G2E3,CCDC88A,SLC12A2,YPEL5,MEGF10,MYT1L,RAPGEF6,CENPJ,HSPH1,IKBIP,PCDH17,ANO4,ACSL6,TDG,TFDP1,LINC01551,RASSF6,TMPO,HSP90B1,HTR2A,JCHAIN,CHPT1" MicroRNA hsa-miR-520h:mirSVR_highEffct hsa-miR-520h:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.75E-20 3.59E-16 4.40E-19 4.03E-18 61 1324 "RALGAPA1,WDR35,APC,MSH2,ZNF542P,CDKL2,CAST,CCNB1,PAH,FAM177A1,CDK17,PDE4D,PGGT1B,POLE,LYSMD3,PRKD1,SPATA18,TBC1D4,TINF2,G3BP2,WDR1,NR1H4,FAM129A,RB1,RNASEL,TXNDC15,UGT2A3,ELK3,ETF1,ELOVL7,TNFRSF19,PIBF1,FOXG1,SELP,HSD17B7,SLC34A2,FBXO11,G2E3,NBEA,ARHGEF40,NR5A2,KDM5B,GJB6,NPAS3,ANKLE2,LRCH1,ZBTB37,ZNF544,LINC02393,GOLGA3,TMPO,RIMBP2,MAEL,TECRL,NPHS2,KCNN2,FIP1L1,TTC41P,RMST,LMNB1,LOX" MicroRNA hsa-miR-617:mirSVR_lowEffct hsa-miR-617:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.96E-20 3.70E-16 4.53E-19 4.15E-18 64 1450 "SNX24,ZNF542P,MYBPC1,NRL,CD1E,ZNF664,PCCA,XPR1,GNPTAB,LYSMD3,CSNK1G3,DCAF8,EPS8L1,PTPRC,MTX3,DHFR,RAN,EGLN3,RASA1,GRTP1,KLHL12,MARVELD2,STK32B,ABCA11P,PCGF3,POLK,MROH9,FLT1,SUPT20H,ZNF446,UFM1,NR5A2,KDM5B,NMNAT2,NAAA,ERAP1,KDM3B,RBKS,NEDD1,LRCH1,PPARGC1A,GJB2,MAST4,PPIP5K2,GOLGA3,ADGRL3,ADGRA3,LILRB4,RNF17,TGFBI,RIMBP2,ADAMTS19,UBE2K,HMGCR,GUF1,VRK2,DCP2,IGF1,TADA2B,ZBED3-AS1,CHPT1,KCNJ9,TTC41P,AXDND1" MicroRNA hsa-miR-4320:mirSVR_highEffct hsa-miR-4320:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.35E-20 3.91E-16 4.78E-19 4.38E-18 46 757 "SMIM15,IL17D,TMEM132B,ANKRD34B,CD84,CBLN3,PCDH9,CDK18,RGSL1,CHD1,THAP6,HOMER1,AKAP6,NGDN,CEP135,FAM169A,SPATA18,PIGG,CEP350,TINF2,TMEM161B,ZNF329,LATS2,MARVELD2,ETF1,VEZT,MBIP,UFM1,FAM114A1,TMEM183A,RBKS,IKBIP,KLHL20,TCF7,ARHGEF28,TDG,AP4S1,ADAMTS19,GUF1,ANKS1B,ZMYM2,FAM151B,KCNN2,AMTN,RNASE11,SPATA13" MicroRNA hsa-miR-320d:mirSVR_highEffct hsa-miR-320d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.70E-20 4.09E-16 5.00E-19 4.58E-18 62 1369 "SFTA3,SMIM15,SEMA6A,WDR19,CACNA1E,LDB2,PCCA,PCDH9,ZMYM5,RGSL1,GLT1D1,RCBTB2,VIT,LINC01085,BOD1L1,THAP6,AKAP6,POU2F1,CLOCK,CEP135,SPATA18,SREK1,DMXL1,TBC1D4,CEP120,SUPT7L,FAM129A,RASA1,LRPPRC,EIF2D,RNASEL,GRTP1,EIF2B1,ZNF671,EFS,ADGRV1,PCGF3,USP44,NDUFAF7,PIBF1,SUPT20H,VEZT,ZCCHC8,FBXO11,MBIP,C1orf112,LIMCH1,GABRB1,PDS5B,INSM2,ATP11A,PPIP5K2,METAP2,C5orf56,TDG,BAZ1A,MAEL,RXFP2,SPTSSA,ANKS1B,NPHS2,MFSD2B" MicroRNA hsa-miR-34c-5p:mirSVR_highEffct hsa-miR-34c-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.84E-20 4.17E-16 5.09E-19 4.66E-18 50 900 "SMIM15,MDM4,BIRC6,COG6,BLZF1,NCOA1,NFATC4,ARHGEF7,CDKL2,FCHO2,CDK18,PDGFRA,CHD1,CCDC122,JAKMIP1,HECTD1,AKAP6,STRN3,TAPT1,EPGN,LRRTM2,DNM3,NOS1AP,ZFYVE16,SREK1,COG3,PPP2R3C,SMC6,RNASE2,RNASEL,SUCO,FOXG1,WDCP,CMPK2,RBKS,LRCH1,ANO4,DOCK9,TGFBI,TNR,GPN1,TUBA3C,WDR36,CCDC169,PLB1,LINC00272,CHPT1,KIT,LAD1,ZNF304" MicroRNA hsa-miR-576-3p:mirSVR_highEffct hsa-miR-576-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-20 4.59E-16 5.59E-19 5.12E-18 52 976 "MAP1B,ANKRD34B,WDR35,WDR19,CDKL2,AMDHD1,FCHO2,PCSK1,CDK17,PDGFRA,SNX6,HOMER1,STRN3,IL20,MPHOSPH8,FCRL5,ZFYVE16,BIVM,DMXL1,PTPRC,SLC9C2,TBC1D19,ARSK,PCBD2,FNIP1,SUPT20H,PAICS,CCDC88A,MYT1L,ATP8A2,HSPH1,KDM3B,MCCC2,MIMT1,ZBTB37,PPARGC1A,BRD8,ADGRL3,C5orf56,STON1,DOCK9,KHNYN,RNF212,TGFBI,TENT2,DCP2,MZF1,IL6ST,PLB1,TMEM178A,LINC00442,AXDND1" MicroRNA hsa-miR-3172:mirSVR_lowEffct hsa-miR-3172:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.03E-20 4.80E-16 5.84E-19 5.35E-18 72 1808 "SLAMF6,NYNRIN,FBRSL1,MSH2,FAM193A,ASCL1,BCL2L2,CD84,ARHGEF7,RAB29,MPZL1,CAST,CD1E,UHMK1,RFLNA,FAM177A1,ZNF595,SLC25A3,SMIM14,BOD1L1,THAP6,TAPT1,POU2F1,HEATR5A,LYSMD3,C12orf65,CEP135,CMTM5,ZNF586,MATR3,BIVM,TBC1D4,PPP2R3C,ZNF329,EFNA5,GORAB,POLK,FLT1,HSD17B7,GOLGA2P5,SGCG,DDX51,BRMS1L,NUBPL,ZNF605,SLC22A4,YPEL5,EFR3B,OXGR1,MIMT1,COMMD6,GJB2,PSME4,ANO4,EML4,DOCK9,KHNYN,YIPF7,TFDP1,CRB1,LINC01551,MAEL,ZNF876P,NLRP8,ZNF10,ZFHX2,ZNF470,SELENOI,ANKS1B,IRF1,ANKDD1B,IFT88" MicroRNA hsa-miR-411*:mirSVR_highEffct hsa-miR-411*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.06E-20 4.82E-16 5.86E-19 5.36E-18 58 1210 "MAP1B,SMIM15,IL17D,COG6,ARL1,NCOA1,NLRP4,CDKL2,RILPL1,CDK7,ITGBL1,NRXN1,SMIM14,THAP6,HOMER1,TAPT1,HEATR5A,LYSMD3,CLOCK,CSNK1G3,FAM169A,NUDT12,OCIAD1,SACS,RABGAP1L,PPP2R3C,REST,LRPPRC,RNASEL,RNF4,CWC27,FNIP1,PIBF1,POLK,SUCO,FOXO1,SUPT20H,VEZT,NLRP2,SLC30A6,SLC12A2,C1orf112,TMEM183A,ATP8A2,SULT1E1,PPARGC1A,TBC1D1,PPIP5K2,METAP2,ADGRA3,ANO4,ADAMTS19,KCNT2,ANKS1B,ZMYM2,LHX9,AXDND1,LOX" MicroRNA hsa-miR-4292:mirSVR_lowEffct hsa-miR-4292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.30E-20 4.95E-16 6.00E-19 5.50E-18 68 1631 "KIAA1211,SEMA6A,FBRSL1,MSH2,ATP1A2,SLC4A4,PPP1R12B,ARHGEF7,MPZL1,LDB2,SCFD2,CDK18,PDGFRA,VIT,PTPRVP,RCHY1,KIAA0040,FCRL5,NOS1AP,EPS8L1,DHFR,SLC35F6,NR1H4,FAM228A,RGS4,POLR1D,KIRREL1,LGR6,FAM172A,ETF1,IRF9,TACC3,PEAR1,HSD17B7,VEZT,SGCG,SLC34A2,SLC8A1,SLC22A5,ACIN1,LIMCH1,CYP1B1-AS1,NMNAT2,GCKR,MCCC2,MAST4,MTUS2,ADGRL3,LILRB4,RIPK3,KMT5C,XPO4,NCSTN,NPL,TPO,ADAMTS19,HPCAL1,MZF1,JCHAIN,PLB1,IRF1,LINC00272,ZBED3-AS1,LAD1,MFSD2B,LINC01913,NUAK2,CDK2AP1" MicroRNA hsa-miR-146b-5p:mirSVR_lowEffct hsa-miR-146b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.49E-20 5.05E-16 6.12E-19 5.60E-18 73 1855 "SFTA3,ADD1,COG6,RGS5,ARL1,FAM193A,LINC02347,CDKL2,AMDHD1,NFXL1,PCDH9,DCLK1,SCFD2,TM9SF2,LINC01085,SNX6,COPA,RCHY1,GALNT9,C12orf65,PIGG,FBXL5,TBC1D4,CEP120,GNPDA2,EGLN3,RASA1,RNASEL,MBNL2,ELF1,ELK3,DHRS2,GP6,EFS,FAM81B,ETF1,ADGRV1,FCAR,UTP15,LRRN2,FLT1,ZCCHC8,PAICS,SLC30A6,ARHGEF40,TADA1,ZNF605,PKD2L2,EFR3B,LIMCH1,PDS5B,ERAP1,GJB6,NPAS3,IKBIP,CFHR4,STRN,PPIP5K2,LILRB4,RNF212,RNF17,TEP1,TFDP1,RAB2B,TENT2,WDR36,ZNF10,KIF3C,KIR2DL1,KIR3DL1,FAM71C,LMNB1,CDK2AP1" MicroRNA hsa-miR-644:mirSVR_lowEffct hsa-miR-644:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-19 5.46E-16 6.61E-19 6.05E-18 63 1419 "MCC,ULK1,ADCY4,BLZF1,CENPBD1P1,ATP1A2,CADM3,ATP7B,CD84,BTF3,LINC02347,LDB2,CD1E,PCDH9,RGSL1,VIT,PTPRVP,C1orf116,COPA,POU2F1,SNCAIP,LRRTM2,DMXL1,RASA1,ZNF329,RGS12,SETDB2,PACRGL,RNASEL,LATS2,RNF4,EIF2B1,UGT2A3,ELK3,LGR6,MARVELD2,CWC27,SH3YL1,FLT1,SH3BP2,CCDC88A,CGREF1,CYP1B1-AS1,GABRA2,PDS5B,ATP8A2,NPAS3,BRD8,ANO4,C5orf56,TCF7,RIPK3,ARHGEF28,RNF212,GPR161,LINC01551,RIMBP2,UBE2K,IL25,NSD2,IL6ST,RILPL2,RMST" MicroRNA hsa-miR-4294:mirSVR_lowEffct hsa-miR-4294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-19 6.05E-16 7.32E-19 6.70E-18 62 1380 "MDM4,ADD1,CUL4A,RGS5,ZNF784,FAM193A,ATP1A2,MYBPC1,CD84,NOVA1,FCGR2C,FAM177A1,PDGFRA,GLT1D1,PIWIL1,PFKFB2,WDFY2,ATAD2B,JAKMIP1,LTB4R,THAP6,COPA,TOGARAM2,NCOR2,SNCAIP,IL20,VCAN,FAM169A,CEP120,DNMT3A,ATG10,RB1,ZNF329,GUSBP3,CWC27,F7,FCAR,TOMM40L,POLK,VEZT,G2E3,DDX51,SLC30A6,N4BP2,NAAA,NFASC,LILRB1,LPIN1,ACSL6,GPR12,RNF17,FZD10,TPO,HMGCR,SLAIN1,TADA2B,ANKS1B,TDRD3,ZBED3-AS1,CHPT1,KIF3C,EP400P1" MicroRNA hsa-miR-127-5p:mirSVR_highEffct hsa-miR-127-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-19 7.44E-16 8.99E-19 8.23E-18 53 1025 "ADD1,BLZF1,STXBP6,CCNA1,TAF1B,FCHO2,PAH,FAM177A1,PCSK1,ATAD2B,THAP6,POU2F1,LYSMD3,MPHOSPH8,PRKD1,CEP350,PTPRC,SACS,SUPT7L,RNF219,NR1I3,NR1H4,RB1,ARGLU1,CLIP4,LATS2,DCUN1D2,ARSK,CWC27,ADGRV1,NDUFAF7,POLK,SUPT20H,VEZT,FBXO11,NUBPL,UFM1,PKD2L2,YPEL5,MEGF10,GABRA2,ADCY10,NPAS3,RBKS,PSME4,TCF7,COX18,RAB2B,TMPO,TNR,TPO,GUF1,AXDND1" MicroRNA hsa-miR-4259:mirSVR_highEffct hsa-miR-4259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-19 7.53E-16 9.09E-19 8.32E-18 41 603 "SFTA3,NLN,APC,NCOA1,FCGR2C,SLC5A8,PCK2,RGSL1,PGGT1B,SLC25A3,JAKMIP1,EIF2AK2,COG3,DCT,PTPRH,RASA1,TMEM161B,MBNL2,EIF2B1,IRF9,HSD17B7,PAICS,UFM1,THADA,MEGF10,PDS5B,CENPJ,EAPP,NPAS3,KLHL20,BRD8,PSME4,TMED2,GOLGA3,MAEL,HMGCR,PAPPA2,DCP2,AMTN,RMST,AXDND1" MicroRNA hsa-miR-125a-5p:mirSVR_lowEffct hsa-miR-125a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-19 8.44E-16 1.02E-18 9.31E-18 65 1517 "ADD1,COG6,SNX24,APC,SLC4A4,ZNF542P,B4GALT3,CACNA1E,FCHO2,SCARB1,FCRLB,DCLK1,CDK17,PDGFRA,CHD1,CFAP54,NRXN1,PTPRVP,HOMER1,NCOR2,ITSN2,CMTM5,MPHOSPH8,NOS1AP,ZNF586,DMXL1,TINF2,DHFR,LATS2,KIRREL1,MPHOSPH9,GP6,ZNF219,STK32B,RELL1,FLT3,ZCCHC8,NLRP2,THADA,CHFR,CYP1B1-AS1,MYT1L,KIF21B,NFASC,ZBTB37,LPIN1,TBC1D1,UTP20,LINC02393,TCF7,KMT5C,KHNYN,TDG,CRB1,GPR161,BAZ1A,HMGCR,TMEM174,PGAM5,ANKDD1B,CAB39L,DIAPH3,NUAK2,TTC7A,ZNF304" MicroRNA hsa-miR-498:mirSVR_highEffct hsa-miR-498:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-19 9.22E-16 1.11E-18 1.02E-17 52 992 "MATN3,ADD1,WDR35,FAM193A,NCOA1,MYBPC1,CACNA1E,CAST,ODC1,CD1D,CD1E,PAH,PCDH9,ZMYM5,SCFD2,CDK17,CHD1,ATAD2B,AKAP6,BIVM,SREK1,PTPRC,GNPDA2,SUPT7L,TSEN15,EGLN3,IPO4,CLIP4,POLR1D,KLHL12,BORA,STX2,ARSK,FCAR,TNFRSF19,TM9SF1,STPG4,THADA,SF3B6,MEGF10,NAAA,IKBIP,PPIP5K2,EML4,RASSF6,ACTR6,ATP6V0A2,HSD17B4,KCNT2,SPTSSA,ANKS1B,RMST" MicroRNA hsa-miR-454*:mirSVR_lowEffct hsa-miR-454*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-19 9.76E-16 1.17E-18 1.07E-17 47 810 "IL17D,COG6,UVSSA,ARHGAP5,ARL1,AACS,FGFRL1,BCL2L2,NOVA1,CBLN3,FCHO2,PDGFRA,CFL2,SMIM14,TAPT1,SYCP3,ZNF586,DCAF8,SPATA18,DMXL1,GNPDA2,RB1,ZNF329,EFNA5,LATS2,UGT2A3,ELF1,LGR6,ABCA11P,SLC22A17,FCAR,IVNS1ABP,THADA,MRPS14,MYT1L,NMNAT2,LRCH1,STON1,KMT5A,DOCK9,KHNYN,NT5C1B,GTF2H3,MZF1,ZMYM2,LHX9,AXDND1" MicroRNA hsa-miR-302d:mirSVR_highEffct hsa-miR-302d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.87E-19 9.95E-16 1.20E-18 1.09E-17 64 1479 "MDM4,KIAA1211,B4GALT3,ARHGEF7,CCNA1,CACNA1E,FCRLB,RFLNA,ZNF664,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,SNCAIP,C12orf65,ITSN2,CEP135,FCRL5,SPATA18,DMXL1,G3BP2,RABGAP1L,GNPDA2,PARPBP,CLIP4,NTN4,LRPPRC,RNASEL,LATS2,MPHOSPH9,STX2,DRAM1,DNAJC27,IRF9,RELL1,PIBF1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,ARHGEF40,MYT1L,CENPJ,ZBTB37,PPIP5K2,ADGRL3,GPR12,KMT5C,TDG,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-219-2-3p:mirSVR_highEffct hsa-miR-219-2-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-19 1.00E-15 1.20E-18 1.10E-17 56 1149 "DDX55,ARL1,AACS,NFATC4,ARHGEF7,BTF3,CAST,LDB2,SNTG2,SLC5A8,SCFD2,RCBTB2,THAP6,NGDN,FCRL5,ZNF586,ZFYVE16,SPATA18,SREK1,LOC439933,NUDT12,G3BP2,DHFR,CLIP4,RNASEL,SPATA9,MPHOSPH9,DHRS2,GP6,MAEA,TRAPPC13,PCBD2,PIBF1,FLT3,G2E3,ZNF605,SLC12A2,UGGT2,GABRB1,OXGR1,GC,KLHL20,BRD8,TMED2,COX7B2,KMT5A,NT5C1B,AP4S1,MAEL,ADAMTS19,UBE2K,GPN1,TECRL,VRK2,IL6ST,CHPT1" MicroRNA hsa-miR-4252:mirSVR_highEffct hsa-miR-4252:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.91E-19 1.01E-15 1.21E-18 1.11E-17 41 608 "NDRG2,MSH2,ARHGEF7,CAMK4,LDB2,PCCA,PCDH9,CDK17,PDGFRA,PFKFB2,ATAD2B,JAKMIP1,LTB4R,AKAP6,KIAA0040,FCRL5,ZFYVE16,PARPBP,RNF219,FAM129A,ATG10,GUSBP3,TOMM40L,FOXG1,IVNS1ABP,KDM5B,SRP72,ZNF544,TMED2,LINC02393,ZBTB49,GTF3C2,ADAMTS19,ZNF324B,IL6ST,CCDC169,ZMYM2,KIR2DL4,KIT,TTC41P,AXDND1" MicroRNA hsa-miR-4330:mirSVR_highEffct hsa-miR-4330:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.91E-19 1.02E-15 1.22E-18 1.11E-17 45 741 "RALGAPA1,MDM4,NDRG2,NOVA1,CAST,LDB2,NRXN1,THAP6,CLOCK,CEP135,PRKD1,ZNF586,MATR3,PTPRC,PARPBP,FAM228A,RGS12,LRPPRC,RNASEL,CLIP1,TRAPPC13,GORAB,MROH9,HSD17B7,RUBCNL,UFM1,WDCP,FSHR,YPEL5,ACIN1,UGGT2,KDM5B,DRC1,LRCH1,SULT1E1,PPARGC1A,METAP2,NT5C1B,ZNF550,UGT2B7,ZNF10,PLB1,FIP1L1,TTC41P,LAD1" MicroRNA hsa-miR-520g:mirSVR_highEffct hsa-miR-520g:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-19 1.03E-15 1.23E-18 1.12E-17 62 1395 "RALGAPA1,WDR35,APC,MSH2,ZNF542P,CDKL2,CAST,CCNB1,PAH,FAM177A1,CDK17,PDE4D,PGGT1B,POLE,LYSMD3,PRKD1,SPATA18,TBC1D4,TINF2,G3BP2,WDR1,NR1H4,FAM129A,RB1,RNASEL,TXNDC15,UGT2A3,ELK3,ETF1,ELOVL7,TNFRSF19,PIBF1,FOXG1,SELP,HSD17B7,ZCCHC8,SLC34A2,FBXO11,G2E3,NBEA,ARHGEF40,NR5A2,KDM5B,GJB6,NPAS3,ANKLE2,LRCH1,ZBTB37,ZNF544,LINC02393,GOLGA3,TMPO,RIMBP2,MAEL,TECRL,NPHS2,KCNN2,FIP1L1,TTC41P,RMST,LMNB1,LOX" MicroRNA hsa-miR-616:mirSVR_highEffct hsa-miR-616:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-19 1.08E-15 1.29E-18 1.18E-17 47 812 "MDM4,ADD1,COG6,BLZF1,CAST,LDB2,FCGR2C,ZNF664,PCDH9,PCK2,ZMYM5,CDK17,CHD1,TAPT1,EPGN,IL20,C12orf65,SNX17,LOC439933,CEP350,TSEN15,RASA1,RB1,TMEM161B,RGS12,MARVELD2,CWC27,HSD17B7,SLC12A2,NR5A2,NFASC,GC,RBKS,UGT2A1,ADAM17,PPIP5K2,LILRB4,GPR12,STON1,MAEL,TPO,TXK,C12orf73,ZMYM2,ANKDD1B,FIP1L1,RMST" MicroRNA hsa-miR-21*:mirSVR_highEffct hsa-miR-21*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.20E-19 1.17E-15 1.40E-18 1.28E-17 57 1193 "COG6,SNX24,MSH2,BLZF1,NFATC4,ARHGEF7,PCK2,CDK17,PDE4D,GPR180,AKAP6,PREPL,VCAN,PRKD1,LOC439933,TBC1D4,OCIAD1,NR1H4,ATG10,AASDH,DTD2,RGS4,RGS12,NTN4,RNASEL,TXNDC15,ETF1,CLIP1,USP44,FCAR,NDUFAF7,FLT3,FBXO11,BRMS1L,PAICS,UFM1,SCYL2,IVNS1ABP,WDCP,YPEL5,MYO16,NAAA,NEDD1,ERBIN,PSME4,INSM2,PPIP5K2,EML4,COP1,NT5C1B,AP4S1,TMPO,HAL,SELENOI,ZMYM2,RMST,CDK2AP1" MicroRNA hsa-miR-1301:mirSVR_highEffct hsa-miR-1301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.23E-19 1.18E-15 1.41E-18 1.29E-17 49 886 "MDM4,CUL4A,AACS,FCRL3,CCNA1,CDK17,RGSL1,MRPL57,ZNF586,ZFYVE16,SNX17,BIVM,COG3,NUDT12,G3BP2,FAM129A,RB1,TMEM161B,ZNF419,TXNDC15,LGR6,DNAJC27,PCBD2,TOMM40L,RELL1,SUCO,FLT1,RASA3,FBXO11,NUBPL,IVNS1ABP,SLC12A2,SLC22A4,YPEL5,ACIN1,MYT1L,NAAA,SULT1E1,PPARGC1A,PSME4,ANO4,RIPK3,LINC01551,HEXB,TPO,DCP2,FCRL6,FAM151B,LMNB1" MicroRNA hsa-miR-188-3p:mirSVR_highEffct hsa-miR-188-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-19 1.29E-15 1.53E-18 1.40E-17 53 1038 "SNX24,SLC4A4,CD84,CD1D,CDK18,PDGFRA,PGGT1B,WDFY2,STRN3,THTPA,LYSMD3,SNCAIP,PRKD1,ZNF586,ZFYVE16,DMXL1,F11R,RABGAP1L,DNMT3A,RAN,KLHL12,LGR6,BORA,CWC27,ETF1,DLEU1,SUCO,SDC1,FLT1,VEZT,TM9SF1,RUBCNL,G2E3,UFM1,TADA1,CCDC88A,C1orf112,SLC22A4,TMEM183A,OXGR1,ZBTB37,ZNF544,CRB1,TMPO,ADAMTS19,HSP90B1,SLAIN1,ZNF26,ZNF140,ZBED3-AS1,CHPT1,KIT,AXDND1" MicroRNA hsa-miR-1184:mirSVR_highEffct hsa-miR-1184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-19 1.31E-15 1.55E-18 1.42E-17 50 925 "CUL4A,ARHGAP5,AACS,ARHGEF7,CCNA1,SNTG2,CDK17,RGSL1,ITGBL1,FAM163A,SNCAIP,VCAN,DNM3,SPATA18,EPS8L1,PIGG,TBC1D4,SACS,SUPT7L,NR1H4,RAN,AASDH,RNASEL,MBNL2,TRAPPC12,SNORA49,LGR6,DLEU1,ADGRV1,FCGR2B,TOMM40L,PIBF1,SELP,SUPT20H,ACIN1,LIMCH1,PDS5B,NPAS3,METAP2,TDG,NCSTN,CRB1,ZBTB49,RIMBP2,ADAMTS19,KCNJ9,KIR2DL4,KIR3DL2,LCP1,LMNB1" MicroRNA hsa-miR-514b-3p:mirSVR_highEffct hsa-miR-514b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-19 1.32E-15 1.56E-18 1.43E-17 45 746 "MATN3,NLN,ANKRD34B,CUL4A,MCFD2,MSH2,NCOA1,CAMK4,PCCA,FAM177A1,RGSL1,CENPC,ITGBL1,STRN3,HEATR5A,CSNK1G3,FAM169A,SPATA18,RABGAP1L,C12orf42,PARPBP,NR1H4,DTD2,PACRGL,DLEU1,RELL1,PIBF1,SUCO,PEAR1,FLT1,ZCCHC8,RUBCNL,ZNF667,NPAS3,MCCC2,NEDD1,ERBIN,INSM2,LINC02393,TEP1,KLF12,GUF1,AXDND1,LIG4,LOX" MicroRNA hsa-miR-1910:mirSVR_highEffct hsa-miR-1910:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.51E-19 1.33E-15 1.58E-18 1.45E-17 44 712 "MAP1B,SMIM15,CDKL4,MSH2,NOP14,ZNF542P,BCL2L2,UHMK1,CDK17,HOMER1,SNCAIP,FCRL5,DCAF8,SNX17,BIVM,G3BP2,B3GLCT,ATG10,ABCA11P,PCGF3,ELOVL7,IRF9,FCAR,GORAB,VEZT,RUBCNL,SCYL2,SLC22A4,PDS5B,RAPGEF6,SRP72,DRC1,LRCH1,PPIP5K2,ANO4,CRB1,GPR161,GTF2H3,GTF3C2,NPL,WDR36,JCHAIN,TTC41P,SKA3" MicroRNA hsa-miR-769-3p:mirSVR_lowEffct hsa-miR-769-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.55E-19 1.36E-15 1.60E-18 1.47E-17 61 1361 "MATN3,ADORA1,MSH2,ZNF784,ASTN1,CCNB1IP1,ZNF542P,CD84,NEDD8,LINC02347,PNP,TAF1B,LDB2,PCCA,CDK18,PDE4D,PDGFRA,CHD1,HECTD1,PTPRVP,THAP6,HEATR5A,CLOCK,SPATA18,LOC439933,OCIAD1,PTPRH,GUSBP3,DCUN1D2,EIF2B1,CWC27,SAP18,ETF1,GMPR2,F10,PIBF1,HSD17B7,PLEKHA6,POTEM,EFR3B,CYP1B1-AS1,CIDEB,PDS5B,TMEM183A,HSPH1,METAP2,STON1,CRB1,TXK,WDR36,NSD2,ZNF10,MZF1,PLB1,GALP,FIP1L1,CAB39L,AMTN,DNAH10,SPRYD7,LOX" MicroRNA hsa-miR-320e:mirSVR_lowEffct hsa-miR-320e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-19 1.40E-15 1.65E-18 1.51E-17 74 1936 "SFTA3,BIRC6,ADD1,ANKRD34B,COG6,WDR35,SEMA6A,ULK1,HOMEZ,APC,BLZF1,WDR19,ARHGAP5,ARL1,ASTN1,NFATC4,CHAMP1,LDB2,CD1E,PCDH9,DCLK1,PDE4D,PDGFRA,PFKFB2,CHIT1,MRPL57,BOD1L1,JAKMIP1,AKAP6,MPHOSPH8,FCRL5,COG3,DMXL1,CEP120,GNPDA2,RASA1,OGFOD2,IPO4,NTN4,RNASEL,EIF2B1,MPHOSPH9,MARVELD2,CLIP1,F7,SH3YL1,PIBF1,FOXO1,STPG4,IVNS1ABP,SLC12A2,MYT1L,FAM114A1,NMNAT2,ZNF274,NFASC,INSM2,MTUS2,CNTN2,GPR12,NCSTN,GRSF1,NPL,HEXB,GPN1,ARHGAP30,VRK2,PLB1,ZBED3-AS1,KIF3C,KIR2DL4,LETM1,NUAK2,LMNB1" MicroRNA hsa-miR-337-3p:mirSVR_highEffct hsa-miR-337-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.64E-19 1.40E-15 1.66E-18 1.52E-17 55 1118 "BLZF1,ATP12A,FCHO2,SCARB1,PCDH9,RGSL1,THAP6,AKAP6,THTPA,SNCAIP,MPHOSPH8,ZNF586,COG3,DMXL1,OCIAD1,PARPBP,TSEN15,RASA1,RB1,AASDH,ELF1,TBC1D19,FAM172A,MAEA,FGFR3,RELL1,PIBF1,TM9SF1,UFM1,ARHGEF40,CCDC88A,PKD2L2,ZNF667,KIF21B,NAAA,TMEM183A,ERAP1,ATP8A2,HSPH1,SRP72,PPARGC1A,GJB2,PPIP5K2,CRB1,LINC01551,GTF2H3,RIMBP2,GPN1,TENT2,ZNF10,CHPT1,FIP1L1,AXDND1,LIG4,PABPN1" MicroRNA hsa-miR-4287:mirSVR_lowEffct hsa-miR-4287:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.69E-19 1.43E-15 1.68E-18 1.54E-17 70 1754 "LRRC43,BIRC6,WDR35,SEMA6A,ASTN1,ATP1A2,ATP2B4,KCTD12,BCL2L2,NOVA1,CACNA1E,CDKL2,PCDH9,SCFD2,CFL2,CCDC122,WDFY2,PIK3C2B,HOMER1,CLOCK,LACC1,FAM169A,FCRL5,NOS1AP,EPS8L1,NR1I3,SMC6,RGS12,RNF4,DCUN1D2,KLHL12,GP6,ZNF219,CWC27,MAEA,CLIP1,FCAR,FCGR3A,TOMM40L,FCGR3B,FNIP1,FLT1,SLC34A2,NBEA,THADA,WDCP,GABRA2,GABRB1,JPH4,CD244,HSPH1,MRPS27,CMPK2,NFASC,MCCC2,LRCH1,PPIP5K2,MTUS2,GOLGA3,TECRL,GUF1,FCRL6,CHPT1,KCNJ9,LAD1,AXDND1,IFT88,PABPN1,LOX,ZNF304" MicroRNA hsa-miR-1224-3p:mirSVR_lowEffct hsa-miR-1224-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.99E-19 1.59E-15 1.87E-18 1.71E-17 68 1668 "LRRC43,NLN,TBC1D14,HOMEZ,DHX37,PPFIA4,MSH2,BLZF1,CCNB1IP1,MYBPC1,NFATC4,AMDHD1,RILPL1,SCARB1,PCCA,PDGFRA,CENPC,PIWIL1,WDFY2,BOD1L1,LYSMD3,LRRTM2,CEP135,DCAF8,EPS8L1,G3BP2,SLC35F6,LINC01257,C14orf119,ATG10,RNF31,MEMO1,LRPPRC,F7,PCBD2,TMEM156,FCGR3A,FCGR3B,POLK,FLT3,HSD17B7,SLC34A2,NUBPL,ZNF605,LIMCH1,CYP1B1-AS1,MYO16,MEGF10,PDS5B,JPH4,KDM3B,ZNF544,ATP11A,GOLGA3,STON1,FCRLA,MSH6,LINC01551,AP4S1,TNNT2,TNR,UBE2K,TXK,GUF1,NSD2,YTHDC2,AXDND1,IFT88" MicroRNA hsa-miR-591:mirSVR_lowEffct hsa-miR-591:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-19 1.62E-15 1.90E-18 1.74E-17 58 1242 "RALGAPA1,BIRC6,ADD1,ATP6V1G3,COG6,WDR35,MCFD2,ATP1A2,NLRP4,ATP7B,CDK17,PDGFRA,POLN,THAP6,C1orf116,AKAP6,TOGARAM2,SNCAIP,CEP135,DNM3,BIVM,SREK1,OCIAD1,F11R,SACS,PARPBP,PPP2R3C,ZNF329,PACRGL,EFNA5,PCGF3,FCGR3A,FCGR3B,FLT3,RUBCNL,NBEA,UFM1,IVNS1ABP,GABRB1,PDS5B,HSPH1,NPAS3,IKBIP,KLHL20,NPFFR2,ZBTB37,PPIP5K2,GPR12,TCF7,RNF17,AP4S1,ADAMTS19,SLAIN1,ZNF84,CCDC169,ZBTB41,ZBED3-AS1,KCNN2" MicroRNA hsa-miR-595:mirSVR_highEffct hsa-miR-595:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.21E-19 1.71E-15 2.00E-18 1.84E-17 46 786 "NLN,ULK1,DDX55,CAD,CDKL2,ODC1,PAH,CDK17,PDE4D,ATAD2B,HOMER1,THTPA,LYSMD3,NGDN,DMXL1,PARPBP,RASA1,MBNL2,FAM172A,CWC27,STK32B,ADGRV1,SH3YL1,TRAPPC13,GORAB,SUCO,HSD17B7,ARHGEF40,CCDC88A,PKD2L2,GABRA2,ERAP1,ZBTB37,LPIN1,KMT5A,RNF212,TGFBI,GZMH,NPL,GPN1,NSD2,FCRL6,IGF1,AXDND1,IFT88,SPATA13" MicroRNA hsa-miR-1306:mirSVR_lowEffct hsa-miR-1306:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.23E-19 1.72E-15 2.02E-18 1.85E-17 36 463 "WDR35,NOVA1,CAST,LDB2,ZMYM5,LINC01085,PTPRVP,LYSMD3,NCOR2,CSNK1G3,GLT8D2,SPATA18,EPS8L1,OCIAD1,AASDH,LAP3,GUSBP3,PACRGL,ABCA11P,F10,GORAB,STAB2,SUPT20H,LIMCH1,CYP1B1-AS1,TMEM183A,ATP8A2,METAP2,MTUS2,CNTN2,RIPK3,NCSTN,ZBTB49,ZNF721,CCDC169,LINC00442" MicroRNA hsa-miR-520c-3p:mirSVR_highEffct hsa-miR-520c-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.26E-19 1.73E-15 2.03E-18 1.86E-17 61 1368 "MDM4,BIRC6,KIAA1211,B4GALT3,CCNA1,CACNA1E,MORN2,FCRLB,RFLNA,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,PGGT1B,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,C12orf65,ITSN2,CEP135,DCAF8,SPATA18,NUDT12,GNPDA2,IPO4,CLIP4,NTN4,RNASEL,LATS2,MPHOSPH9,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,HSD17B7,VEZT,FBXO11,BRMS1L,SLC30A6,ARHGEF40,YPEL5,MYT1L,ZBTB37,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,TEP1,CRB1,ARHGAP30,C12orf73,ZMYM2,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-1273d:mirSVR_highEffct hsa-miR-1273d:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.52E-19 1.87E-15 2.19E-18 2.01E-17 49 896 "PITPNM2,BLZF1,ASCL1,SLC5A8,XPR1,CDK7,ATAD2B,BOD1L1,AKAP6,HEATR5A,DCAF8,CEP350,OCIAD1,TSEN15,DNMT3A,RB1,AASDH,DTD2,POLR1D,FAM172A,STK32B,ELOVL7,FCAR,GORAB,SDC1,NBEA,SLC8A1,MYT1L,JPH4,NPAS3,NEDD1,TMED2,PPIP5K2,ANO4,RNF212,COP1,TDG,TMPO,SLAIN1,PAPPA2,YTHDC2,ZNF10,C12orf73,ZMYM2,LHX9,LMLN,SPRYD7,CDK2AP1,LOX" MicroRNA hsa-miR-18a:mirSVR_highEffct hsa-miR-18a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.63E-19 1.93E-15 2.26E-18 2.07E-17 44 719 "NCOA1,CAD,PCK2,PCSK1,PDE4D,PDGFRA,NRXN1,ADGRF3,TAPT1,COPA,RNASE9,HEATR5A,MATR3,BIVM,COG3,GNPDA2,SUPT7L,PARPBP,SLC9C2,RNASEL,RNF4,FAM172A,EFS,TRAPPC13,FCGR2B,SUCO,MROH9,C1orf112,YPEL5,KDM5B,NAAA,SRP54,KLHL20,LPIN1,PPARGC1A,PSME4,PPIP5K2,ANO4,YIPF7,NPL,TRPC4,TXK,CHPT1,RMST" MicroRNA hsa-miR-375:mirSVR_lowEffct hsa-miR-375:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.91E-19 2.08E-15 2.43E-18 2.22E-17 51 973 "SMIM15,LRRC43,ATP6V1G3,ANKRD34B,HOMEZ,CCDC181,PPP1R12B,FCRL3,NOVA1,UHMK1,NRXN1,LINC01085,AKAP6,COPA,LYSMD3,PRKD1,ZFYVE16,MATR3,DMXL1,NR1H4,RASA1,DTD2,RNASEL,SPATA9,CWC27,PIBF1,SUCO,FTLP10,NBEA,GFM2,P2RX2,SLC22A4,LIMCH1,MYO16,RBKS,ERBIN,KLHL20,PPARGC1A,MAST4,SPIC,ANO4,STON1,MAEL,NPL,GUF1,SLAIN1,TENT2,CCDC169,ZBED3-AS1,CHPT1,LIG4" MicroRNA hsa-miR-454-3p:TargetScan hsa-miR-454-3p TargetScan 4.03E-19 2.14E-15 2.49E-18 2.28E-17 44 721 "MAP1B,MCC,MDM4,NDRG2,BIRC6,KIAA1211,PITPNM2,NCOA1,CAST,PDE4D,CEBPE,PDGFRA,CFL2,HECTD1,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,KLHL3,G3BP2,EGLN3,MEMO1,EFNA5,SBNO1,ELK3,CLIP1,CCDC88A,MYT1L,IQGAP2,CMPK2,LRCH1,KLHL20,PPARGC1A,ATP11A,BAZ1A,ADAMTS19,DCP2,IGF1,IL6ST,IRF1,LMLN,DIAPH3,KIT" MicroRNA hsa-miR-130b-3p:TargetScan hsa-miR-130b-3p TargetScan 4.03E-19 2.14E-15 2.49E-18 2.28E-17 44 721 "MAP1B,MCC,MDM4,NDRG2,BIRC6,KIAA1211,PITPNM2,NCOA1,CAST,PDE4D,CEBPE,PDGFRA,CFL2,HECTD1,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,KLHL3,G3BP2,EGLN3,MEMO1,EFNA5,SBNO1,ELK3,CLIP1,CCDC88A,MYT1L,IQGAP2,CMPK2,LRCH1,KLHL20,PPARGC1A,ATP11A,BAZ1A,ADAMTS19,DCP2,IGF1,IL6ST,IRF1,LMLN,DIAPH3,KIT" MicroRNA hsa-miR-130a-3p:TargetScan hsa-miR-130a-3p TargetScan 4.03E-19 2.14E-15 2.49E-18 2.28E-17 44 721 "MAP1B,MCC,MDM4,NDRG2,BIRC6,KIAA1211,PITPNM2,NCOA1,CAST,PDE4D,CEBPE,PDGFRA,CFL2,HECTD1,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,KLHL3,G3BP2,EGLN3,MEMO1,EFNA5,SBNO1,ELK3,CLIP1,CCDC88A,MYT1L,IQGAP2,CMPK2,LRCH1,KLHL20,PPARGC1A,ATP11A,BAZ1A,ADAMTS19,DCP2,IGF1,IL6ST,IRF1,LMLN,DIAPH3,KIT" MicroRNA hsa-miR-301a-3p:TargetScan hsa-miR-301a-3p TargetScan 4.03E-19 2.14E-15 2.49E-18 2.28E-17 44 721 "MAP1B,MCC,MDM4,NDRG2,BIRC6,KIAA1211,PITPNM2,NCOA1,CAST,PDE4D,CEBPE,PDGFRA,CFL2,HECTD1,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,KLHL3,G3BP2,EGLN3,MEMO1,EFNA5,SBNO1,ELK3,CLIP1,CCDC88A,MYT1L,IQGAP2,CMPK2,LRCH1,KLHL20,PPARGC1A,ATP11A,BAZ1A,ADAMTS19,DCP2,IGF1,IL6ST,IRF1,LMLN,DIAPH3,KIT" MicroRNA hsa-miR-301b-3p:TargetScan hsa-miR-301b-3p TargetScan 4.03E-19 2.14E-15 2.49E-18 2.28E-17 44 721 "MAP1B,MCC,MDM4,NDRG2,BIRC6,KIAA1211,PITPNM2,NCOA1,CAST,PDE4D,CEBPE,PDGFRA,CFL2,HECTD1,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,KLHL3,G3BP2,EGLN3,MEMO1,EFNA5,SBNO1,ELK3,CLIP1,CCDC88A,MYT1L,IQGAP2,CMPK2,LRCH1,KLHL20,PPARGC1A,ATP11A,BAZ1A,ADAMTS19,DCP2,IGF1,IL6ST,IRF1,LMLN,DIAPH3,KIT" MicroRNA hsa-miR-548f:PITA hsa-miR-548f:PITA_TOP PITA 4.83E-19 2.57E-15 2.98E-18 2.73E-17 47 830 "MAP1B,MCC,SMIM15,TBC1D14,STXBP6,SLC4A4,KCTD12,ARHGEF7,BTF3,PCSK1,PDE4D,ATAD2B,BOD1L1,TAPT1,FAM53A,LYSMD3,CLOCK,DNM3,MPHOSPH8,MATR3,SREK1,COG3,G3BP2,B3GLCT,ETF1,PCGF3,FGFR3,SUCO,FBXO11,SLC8A1,CCDC88A,CHFR,MYT1L,GABRB1,PDS5B,ERBIN,STRN,MTUS2,DOCK9,XPO4,TDG,BAZ1A,NSD2,CENPH,SPTSSA,ZBTB41,KIF2A" MicroRNA hsa-miR-1975:mirSVR_highEffct hsa-miR-1975:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.84E-19 2.57E-15 2.98E-18 2.73E-17 39 560 "SMIM15,NDRG2,NFKBIA,CACNA1E,AMDHD1,ZNF664,PCK2,SCFD2,SNX6,EPGN,BRI3BP,ZNF586,SPATA18,SREK1,RNASEL,DHRS2,BORA,SAP18,FOXG1,GOLGA2P5,TM9SF1,FBXO11,SLC8A1,THADA,CCDC88A,DCAF11,SNRPF,GABRB1,CENPJ,HSPH1,PSME4,C5orf56,RNF17,TGFBI,TMPO,RIMBP2,DCP2,LINC00272,MFSD2B" MicroRNA hsa-miR-760:mirSVR_highEffct hsa-miR-760:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.98E-19 2.65E-15 3.07E-18 2.81E-17 43 691 "LRRC43,ATP6V1G3,CADM3,CAST,CD1E,CFAP54,ATAD2B,PTPRVP,POU2F1,VCAN,FCRL5,CTSG,DMXL1,CEP120,NR1H4,RGS12,POLR1D,RNF4,DEPDC4,FCGR3A,FCGR3B,SLC34A2,ZNF667,YPEL5,CYP1B1-AS1,NMNAT2,TMEM183A,DRC1,IKBIP,ZBTB37,PPIP5K2,TCF7,SLC7A8,TGFBI,GTF3C2,ADAMTS19,HMGCR,PAPPA2,CAB39L,KIF2A,KIF3C,LCP1,LMNB1" MicroRNA hsa-miR-581:mirSVR_lowEffct hsa-miR-581:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.05E-19 2.69E-15 3.10E-18 2.84E-17 68 1685 "MAP1B,COG6,ZNF542P,ATP2B4,NFATC4,BTF3,CCNA1,ADGRD1,CBLN3,CAMK4,UHMK1,CDK17,CHD1,AKAP6,HEATR5A,SNCAIP,LRRTM2,SPATA18,COG3,LOC439933,KLHL3,SUPT7L,ATG10,RB1,LAP3,MEMO1,POLR1D,NTN4,UGT2A3,ELF1,GP6,FAM172A,TOMM40L,GORAB,SUCO,SGCG,C1orf112,YPEL5,PDS5B,IQGAP2,ERAP1,MCCC2,GJA3,PSME4,UGT2A1,TMED2,LINC02393,PPIP5K2,METAP2,ANO4,C5orf56,STON1,FCRLA,TEP1,NT5C1B,TFDP1,AP4S1,MAEL,HAL,UBE2K,TENT2,IGF1,ZFHX2,SELENOI,LHX9,ZBED3-AS1,CDK2AP1,ZNF304" MicroRNA hsa-miR-193b*:mirSVR_lowEffct hsa-miR-193b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.41E-19 2.88E-15 3.32E-18 3.04E-17 71 1823 "SLAMF6,NYNRIN,FBRSL1,MSH2,FAM193A,ASCL1,BCL2L2,CD84,ARHGEF7,RAB29,MPZL1,CAST,CD1E,UHMK1,RFLNA,FAM177A1,ZNF595,SLC25A3,SMIM14,BOD1L1,THAP6,TAPT1,POU2F1,HEATR5A,LYSMD3,C12orf65,CEP135,CMTM5,ZNF586,MATR3,BIVM,TBC1D4,PPP2R3C,ZNF329,EFNA5,GORAB,POLK,FLT1,HSD17B7,SGCG,DDX51,BRMS1L,NUBPL,ZNF605,SLC22A4,YPEL5,EFR3B,OXGR1,MIMT1,COMMD6,GJB2,PSME4,ANO4,EML4,DOCK9,KHNYN,YIPF7,TFDP1,CRB1,LINC01551,MAEL,ZNF876P,NLRP8,ZNF10,ZFHX2,ZNF470,SELENOI,ANKS1B,IRF1,ANKDD1B,IFT88" MicroRNA hsa-miR-340:PITA hsa-miR-340:PITA_TOP PITA 5.42E-19 2.88E-15 3.32E-18 3.04E-17 41 626 "SMIM15,CUL4A,ASCL1,ATP2B4,STARD13,KCTD12,CAST,FCHO2,LDB2,UHMK1,PDGFRA,SNX6,BOD1L1,HOMER1,STRN3,ZFYVE16,COG3,TBC1D4,SACS,G3BP2,GNPDA2,CLIP4,MEMO1,ELF1,PCGF3,FNIP1,SUPT20H,NBEA,MBIP,SLC12A2,ACIN1,MYT1L,PDS5B,PPIP5K2,ADGRL3,KMT5A,GTF3C2,RIMBP2,TRPC4,IGF1,ZBTB41" MicroRNA hsa-miR-1321:mirSVR_highEffct hsa-miR-1321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.12E-19 3.25E-15 3.75E-18 3.43E-17 47 835 "COG6,ATP12A,BTF3,TAF1B,CDK18,ZNF595,WDFY2,HOMER1,SYCP3,SNCAIP,LRRTM2,FCRL5,FBXL5,SLC35F6,C14orf119,AASDH,SLC9C2,CLIP4,LGR6,CWC27,ELOVL7,RELL1,SGCG,CCDC88A,PKD2L2,ACIN1,KIF21B,SRP54,NFASC,ZBTB37,SPIC,ARHGEF28,NCSTN,BAZ1A,FZD10,MAEL,TNR,ARHGAP30,PAPPA2,NSD2,CCDC169,PLB1,KIF3C,KIR2DS4,RNASE11,LINC01913,PABPN1" MicroRNA hsa-miR-501-3p:mirSVR_lowEffct hsa-miR-501-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.23E-19 3.32E-15 3.81E-18 3.49E-17 56 1180 "RGS5,AACS,ATP1A2,ZNF542P,LINC02347,CAMK4,DCLK1,PCK2,CDK17,TM9SF2,SMIM14,TAPT1,GNPTAB,TOGARAM2,LYSMD3,KIAA0040,NOS1AP,PTGS2,NUDT12,F11R,TINF2,GNPDA2,SLC35F6,DNMT3A,FAM129A,SLC9C2,GUSBP3,GP6,ETF1,ADGRV1,PCGF3,TOMM40L,RELL1,SUPT20H,UFM1,EFR3B,MYT1L,JPH4,ATP8A2,NEDD1,COMMD6,GJA3,ANO4,GPR12,KMT5C,DOCK9,XPO4,FCRLA,NPL,KLF12,TENT2,PLB1,TMEM178A,KIF2A,IFT88,LOX" MicroRNA hsa-miR-33b*:mirSVR_lowEffct hsa-miR-33b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.33E-19 3.37E-15 3.87E-18 3.54E-17 60 1345 "SMIM15,ADORA1,KIAA1211,ATP6V1G3,FBRSL1,APC,MSH2,ZNF784,ARL1,NFATC4,RAB29,MPZL1,SCARB1,WDR66,PIK3C2B,GNPTAB,SNCAIP,GALNT9,VCAN,C12orf65,PSME1,COG3,OCIAD1,F11R,SACS,GNPDA2,ATG10,OGFOD2,ETF1,GMPR2,NDUFAF7,PEAR1,SUPT20H,STPG4,TADA1,ZNF605,GABRA2,PDS5B,NMNAT2,JPH4,ERAP1,LRCH1,GJA3,ZNF544,TBC1D1,TCF7,STON1,TFDP1,CRB1,RAB2B,UBE2K,ARHGAP30,TECRL,SLAIN1,IL25,IL6ST,SDR39U1,ZBED3-AS1,KIT,ZNF304" MicroRNA hsa-miR-199a-5p:mirSVR_highEffct hsa-miR-199a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.38E-19 3.39E-15 3.89E-18 3.56E-17 46 800 "RALGAPA1,ZNF542P,CDK7,CFL2,ATAD2B,PREPL,UBXN2A,ZNF586,BIVM,PIGG,CEP120,PTPRC,SACS,WDR1,NR1I3,B3GLCT,ZNF329,ZNF419,TXNDC15,FCAMR,DRAM1,CLIP1,USP44,UTP15,SELP,MROH9,NBEA,IVNS1ABP,POTEM,GABRA2,ALLC,KDM3B,PPARGC1A,ZNF544,METAP2,ANO4,ARHGEF28,TEP1,CRB1,GTF3C2,TMPO,LTB4R2,RXFP2,FCRL6,CHPT1,KIT" MicroRNA hsa-miR-26a:PITA hsa-miR-26a:PITA_TOP PITA 6.46E-19 3.43E-15 3.93E-18 3.60E-17 36 473 "ABL2,MAP1B,ULK1,EP400,ATP1A2,SLC4A4,PCDH9,PDGFRA,ATAD2B,CFAP45,PTGS2,DMXL1,CEP350,TBC1D4,SACS,G3BP2,RB1,RGS4,TMEM33,NTN4,MAEA,FNIP1,RELL1,FBXO11,G2E3,SLC12A2,CHFR,METAP2,COP1,GTF3C2,ADAMTS19,KLF12,UBE2K,TENT2,IGF1,CDK2AP1" MicroRNA hsa-miR-26b:PITA hsa-miR-26b:PITA_TOP PITA 6.46E-19 3.43E-15 3.93E-18 3.60E-17 36 473 "ABL2,MAP1B,ULK1,EP400,ATP1A2,SLC4A4,PCDH9,PDGFRA,ATAD2B,CFAP45,PTGS2,DMXL1,CEP350,TBC1D4,SACS,G3BP2,RB1,RGS4,TMEM33,NTN4,MAEA,FNIP1,RELL1,FBXO11,G2E3,SLC12A2,CHFR,METAP2,COP1,GTF3C2,ADAMTS19,KLF12,UBE2K,TENT2,IGF1,CDK2AP1" MicroRNA hsa-miR-1297:PITA hsa-miR-1297:PITA_TOP PITA 6.46E-19 3.43E-15 3.93E-18 3.60E-17 36 473 "ABL2,MAP1B,ULK1,EP400,ATP1A2,SLC4A4,PCDH9,PDGFRA,ATAD2B,CFAP45,PTGS2,DMXL1,CEP350,TBC1D4,SACS,G3BP2,RB1,RGS4,TMEM33,NTN4,MAEA,FNIP1,RELL1,FBXO11,G2E3,SLC12A2,CHFR,METAP2,COP1,GTF3C2,ADAMTS19,KLF12,UBE2K,TENT2,IGF1,CDK2AP1" MicroRNA hsa-miR-1825:mirSVR_lowEffct hsa-miR-1825:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.64E-19 3.53E-15 4.04E-18 3.70E-17 63 1474 "RALGAPA1,MDM4,ADORA1,ATP6V1G3,EP400,SNX24,WDR19,NCOA1,NOVA1,DAOA,CDK7,CDK18,CHD1,GPR180,HECTD1,AKAP6,GNPTAB,ITSN2,PRKD1,FCRL2,PIGG,LOC439933,CEP350,OCIAD1,SACS,RNF219,OGFOD2,CLIP4,RNASEL,KLHL12,TBC1D19,DLEU1,CLIP1,N4BP2L2,RELL1,SUPT20H,VEZT,FBXO11,NBEA,NUBPL,GFM2,ZNF605,SLC22A5,CHFR,UGGT2,JPH4,MRPS27,CMPK2,PPARGC1A,GJA3,INSM2,METAP2,ARHGEF28,DOCK9,CRB1,TMPO,TPO,ZNF470,IRF1,DIAPH3,TTC41P,FAM71C,LMNB1" MicroRNA hsa-miR-619:mirSVR_highEffct hsa-miR-619:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.69E-19 3.56E-15 4.06E-18 3.72E-17 46 801 "MDM4,NDRG2,WDR35,APC,CDKL4,DAOA,PCDH9,PDGFRA,VIT,LINC01085,SNCAIP,PRKD1,ZNF586,FBXL5,NUDT12,COCH,RABGAP1L,PARPBP,NR1I3,DNMT3A,REST,CLIP4,TXNDC15,CWC27,PIBF1,FOXG1,VEZT,ZCCHC8,WDCP,GABRB1,PDS5B,CENPJ,CD244,HSPH1,DRC1,ANKLE2,ERBIN,STON1,TGFBI,TNR,GUF1,RXFP2,DCP2,IL6ST,TTC41P,LCP1" MicroRNA hsa-miR-296-3p:mirSVR_highEffct hsa-miR-296-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.94E-19 3.69E-15 4.21E-18 3.85E-17 37 504 "PPFIA4,ASTN1,BTF3,CAST,CD1D,PCK2,PDGFRA,CENPC,DHRS1,CPNE6,THAP6,AKAP6,STRN3,FAM163A,RNASE9,GNPTAB,DCAF8,ZFYVE16,PTPRC,FAM129A,PACRGL,GOLGA2P5,MBIP,MYO16,GABRA2,JPH4,SULT1E1,ZBTB37,ZNF544,METAP2,TCF7,GUF1,ZNF324B,IL6ST,PLB1,ZMYM2,AXDND1" MicroRNA hsa-miR-769-5p:mirSVR_lowEffct hsa-miR-769-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.58E-19 4.03E-15 4.59E-18 4.20E-17 62 1435 "MDM4,SEMA6A,SNX24,UVSSA,ARL1,ASTN1,KCTD12,ATP7B,ZMYM5,RGSL1,PDGFRA,DHRS1,PIGR,SMIM14,PIK3C2B,FAM163A,TOGARAM2,DNM3,ZNF586,ZFYVE16,CEP350,PTPRH,C14orf119,POLR1D,GUSBP3,LRPPRC,TRAPPC12,ELF1,KLHL12,EFS,STK32B,TOMM40L,POLK,SUCO,ZNF446,ARHGEF40,SLC15A4,YPEL5,CYP1B1-AS1,MYT1L,ATP8A2,IKBIP,CFHR4,GJA3,ZNF544,MTUS2,ADGRL3,DOCK9,TDG,TEP1,SLC7A8,TMPO,NPL,TPO,ADAMTS19,GPN1,HMGCR,IRF1,TTC41P,LCP1,IFT88,SKA3" MicroRNA hsa-miR-193b:mirSVR_lowEffct hsa-miR-193b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.82E-19 4.16E-15 4.73E-18 4.33E-17 56 1186 "IL17D,ADD1,APC,NOP14,CENPBD1P1,BCL2L2,MPZL1,CAST,PCDH9,XPR1,PDE4D,PDGFRA,NLRC4,AKAP6,TOGARAM2,NOS1AP,MTX3,SLC35F6,GALNT14,RNASEL,TXNDC15,KIRREL1,LGR6,GP6,FAM172A,ETF1,ADGRV1,PCGF3,CLIP1,STAB2,CCDC88A,LIMCH1,ZNF274,CD244,UHRF1BP1L,ERAP1,NPAS3,NFASC,ZBTB37,ZNF544,ATP11A,CNTN2,YIPF7,CRB1,AP4S1,MAEL,ATP6V0A2,NPL,ZNF876P,IRF1,TDRD3,KCNJ9,KIT,RILPL2,TTC41P,SKA3" MicroRNA hsa-miR-548q:mirSVR_highEffct hsa-miR-548q:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.05E-19 4.28E-15 4.87E-18 4.46E-17 38 537 "SNX24,MSH2,CENPBD1P1,LINC02347,LDB2,RCBTB2,FAM163A,SNCAIP,DMXL1,TBC1D4,SUPT7L,CLIP4,RNASEL,GRTP1,TRIM28,MARVELD2,FCAMR,SAP18,ABCA11P,GMPR2,CLIP1,TMEM156,STAB2,VEZT,NBEA,SLC12A2,C1orf112,YPEL5,PDS5B,ATP8A2,CMPK2,ZNF544,YIPF7,ZNF721,GUF1,KCNT2,CHPT1,ANKDD1B" MicroRNA hsa-miR-1260b:mirSVR_lowEffct hsa-miR-1260b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.08E-19 4.29E-15 4.87E-18 4.46E-17 70 1791 "MDM4,TMEM132B,NLN,SNX24,DHX37,PPFIA4,APBB2,BLZF1,CCNB1IP1,KCTD12,NFATC4,CBLN3,RILPL1,CCNB1,DCLK1,CENPC,CHIT1,MRPL57,PIK3C2B,ATAD2B,NCR1,STRN3,TAPT1,NCOR2,ITSN2,LRRTM2,CEP135,PRKD1,DCAF8,BIVM,PIGG,RABGAP1L,SLC35F6,TSEN15,ATG10,RGS4,POLR1D,PACRGL,GP6,DRAM1,MAEA,ETF1,TMEM156,TOMM40L,FLT1,HSD17B7,SGCG,G2E3,DDX51,C1orf112,LIMCH1,PDS5B,NMNAT2,JPH4,RAPGEF6,OXGR1,MRPS27,MAST4,ZNF544,MTUS2,LILRB4,FCRLA,TNNT2,UBE2K,TMEM174,MZF1,CENPH,NUAK2,AXDND1,IFT88" MicroRNA hsa-miR-324-5p:mirSVR_lowEffct hsa-miR-324-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.28E-19 4.40E-15 4.99E-18 4.57E-17 53 1068 "MSH2,DDX55,ZNF784,STARD13,CAST,UHMK1,CDK18,PDE4D,SMIM14,ADGRF3,LTB4R,FAM163A,GNPTAB,THTPA,SNCAIP,KIAA0040,FCRL5,ZNF586,PIGG,FBXL5,SLC9C2,MEMO1,SETDB2,GUSBP3,MARVELD2,GP6,DRAM1,ETF1,DLEU1,ARL6IP4,NDUFAF7,LRRN2,SUCO,ARHGEF40,YPEL5,GABRA2,TMEM183A,NEDD1,LRCH1,ADGRA3,ANO4,TEP1,TFDP1,SLC7A8,RIMBP2,ADAMTS19,ARHGAP30,MZF1,LINC00272,CHPT1,KIR3DL2,MFSD2B,LINC00442" MicroRNA hsa-miR-29a:mirSVR_lowEffct hsa-miR-29a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.29E-19 4.41E-15 4.99E-18 4.57E-17 66 1612 "MCC,NDRG2,BIRC6,KIAA1211,SEMA6A,CUL4A,MSH2,ARHGAP5,AACS,ATP2B4,LINC02347,ADGRD1,CACNA1E,DCLK1,CDK18,CFL2,LINC01085,PTPRVP,STRN3,FAM163A,TAPT1,NCOR2,LACC1,DNM3,FCRL5,NOS1AP,PIGG,DMXL1,TMEM33,SETDB2,SNORA53,KIRREL1,LGR6,DHRS2,ARSK,STK32B,ABCA11P,PCGF3,PCBD2,BRMS1L,SCYL2,C1orf112,EFR3B,ERAP1,ERBIN,PCDH17,PPARGC1A,MAST4,PSME4,ATP11A,XPO4,GPR161,FZD10,UBE2K,TXK,WDR36,NSD2,TADA2B,ZNF324B,CCDC169,PLB1,ZBTB41,LMLN,KIR2DL4,KIR2DS4,LMNB1" MicroRNA hsa-miR-372:mirSVR_highEffct hsa-miR-372:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.37E-19 4.45E-15 5.03E-18 4.61E-17 60 1353 "MDM4,KIAA1211,B4GALT3,ARHGEF7,BTF3,CCNA1,SCARB1,FCRLB,RFLNA,PCDH9,FAM177A1,RGSL1,PDE4D,CFL2,NRXN1,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,ITSN2,CEP135,FCRL5,SPATA18,RABGAP1L,GNPDA2,C14orf119,EGLN3,RNF31,CLIP4,NTN4,RNASEL,LATS2,STX2,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,SELP,HSD17B7,VEZT,FBXO11,BRMS1L,ARHGEF40,CYP1B1-AS1,MYT1L,ZBTB37,PPARGC1A,GPR12,KMT5C,CRB1,ARHGAP30,C12orf73,LHX9,TMEM178A,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-206:mirSVR_highEffct hsa-miR-206:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.44E-19 4.49E-15 5.07E-18 4.64E-17 56 1188 "RALGAPA1,ANKRD34B,DDX55,PNP,DAOA,TAF1B,PDGFRA,SMIM14,POU2F1,ZNF586,DCAF8,MATR3,EPS8L1,COCH,OCIAD1,GNPDA2,WDR1,NR1H4,RASA1,AASDH,DTD2,EIF2D,KLHL12,ADGRV1,NBEA,UFM1,SLC8A1,CGREF1,CD244,NPAS3,LRCH1,PCDH17,PPARGC1A,ADGRA3,ANO4,TCF7,YIPF7,COX18,LINC01551,AP4S1,MAEL,NPL,ADAMTS19,HSP90B1,HMGCR,ZNF550,IGF1,MZF1,ZMYM2,SDR39U1,LHX9,TMEM178A,KIF2A,KIF3C,AXDND1,EEF1AKMT1" MicroRNA hsa-miR-320e:mirSVR_highEffct hsa-miR-320e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.47E-19 4.51E-15 5.09E-18 4.66E-17 43 701 "SNX24,RAD51AP2,FAM193A,NCOA1,CD84,ARHGEF7,BTF3,DAOA,CACNA1E,CAST,CDK18,HOMER1,COPA,POU2F1,CLOCK,SPATA18,OCIAD1,RABGAP1L,RNF31,AASDH,EIF2D,GRTP1,MBNL2,PCGF3,RELL1,TM9SF1,MBIP,UFM1,SLC8A1,WDCP,CYP1B1-AS1,PDS5B,KDM5B,CD244,NMU,COMMD6,ADAM17,TDG,ADAMTS19,KCNT2,ANKS1B,LCP1,SKA3" MicroRNA hsa-miR-885-5p:mirSVR_highEffct hsa-miR-885-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.53E-19 5.07E-15 5.71E-18 5.23E-17 41 636 "MDM4,KIAA1211,SEMA6A,FBRSL1,MSH2,ATP12A,ZNF542P,CAMK4,PCDH9,FAM177A1,CDK17,PDE4D,ITGBL1,UGT2B28,MPC2,RCHY1,VCAN,DCAF8,B3GLCT,RNASEL,CWC27,TRAPPC13,TOMM40L,FGF9,PIBF1,SLC12A2,NAAA,ERBIN,INSM2,EML4,GTF2H3,HAL,ADAMTS19,UBE2K,STARD4,FCRL6,ZNF10,IL6ST,SPTSSA,KIF2A,LCP1" MicroRNA hsa-miR-181a-2*:mirSVR_highEffct hsa-miR-181a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.64E-19 5.13E-15 5.78E-18 5.29E-17 45 773 "RALGAPA1,MDM4,AACS,NOVA1,PNP,MPZL1,FCHO2,CHAMP1,PCCA,FAM177A1,CFL2,CHD1,PGGT1B,AKAP6,LYSMD3,SNCAIP,CSNK1G3,NOS1AP,ZFYVE16,SREK1,PARPBP,RAN,TMEM161B,RNF4,USP44,RELL1,IVNS1ABP,MYO16,KDM5B,NAAA,HSPH1,MRPS27,GPR12,DOCK9,NCSTN,RNF17,ADAMTS19,RXFP2,CCDC169,ZMYM2,ZBED3-AS1,KIF3C,KIR2DS4,AXDND1,ZDHHC20" MicroRNA hsa-miR-610:mirSVR_highEffct hsa-miR-610:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.92E-19 5.27E-15 5.93E-18 5.43E-17 43 704 "CUL4A,APC,MSH2,NFATC4,UHMK1,PDE4D,PDGFRA,LINC01085,SNX6,HOMER1,TAPT1,GNPTAB,LYSMD3,CSNK1G3,BIVM,SPATA18,PIGG,PTGS2,FBXL5,PARPBP,FAM228A,EIF2D,ELK3,SUCO,SELP,RASA3,SLC12A2,PKD2L2,YPEL5,UGGT2,GABRA2,PDS5B,NMNAT2,ERAP1,RBKS,NEDD1,KLHL20,GJA3,TMPO,ADAMTS19,SLAIN1,RMST,PABPN1" MicroRNA hsa-miR-4275:mirSVR_highEffct hsa-miR-4275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-18 5.57E-15 6.26E-18 5.73E-17 50 958 "MAP1B,NLN,CDKL4,BLZF1,ARHGAP5,ATP2B4,BCL2L2,MORN2,FCGR2C,UHMK1,ZMYM5,PDE4D,CHD1,HEATR5A,PREPL,FCRL5,ZFYVE16,MATR3,SREK1,PTPRC,OCIAD1,B3GLCT,AASDH,MBNL2,DCUN1D2,ELF1,STX2,USP44,FGF9,PIBF1,PEAR1,SUPT20H,G2E3,THADA,SLC22A5,GABRA2,IQGAP2,CMPK2,MCCC2,PPARGC1A,ADGRA3,DOCK9,TDG,TMPO,NPL,HEXB,VRK2,DIAPH3,AXDND1,IFT88" MicroRNA hsa-miR-9-5p:TargetScan hsa-miR-9-5p TargetScan 1.09E-18 5.77E-15 6.47E-18 5.93E-17 51 997 "ABL2,MAP1B,NLN,COG6,CUL4A,PITPNM2,ARL1,KCTD12,CACNA1E,PCDH9,CDK18,HECTD1,POU2F1,CLOCK,NCOR2,FAM169A,PIGG,COG3,CEP350,NOP9,SACS,RAN,EGLN3,REST,IPO4,EFNA5,SBNO1,MARVELD2,MAEA,FNIP1,FGF9,SDC1,FOXG1,FOXO1,PLEKHA6,CCDC88A,NR5A2,GABRB1,NFASC,PCDH17,GJA3,ATP11A,PPIP5K2,DOCK9,KHNYN,GRSF1,KLF12,IGF1,C12orf73,IL6ST,IRF1" MicroRNA hsa-miR-571:mirSVR_highEffct hsa-miR-571:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-18 6.00E-15 6.73E-18 6.16E-17 39 574 "NYNRIN,MSH2,ARHGAP5,ATP1A2,SLC4A4,CD1E,CHD1,VIT,SLC25A3,LINC01085,COPA,DMXL1,OCIAD1,RABGAP1L,GNPDA2,FAM129A,MEMO1,GUSBP3,RNASE2,RNASEL,IRF9,FCGR3A,UTP15,FCGR3B,FOXO1,STAB2,SCYL2,KDM5B,NPAS3,TMED2,METAP2,COP1,GTF3C2,TXK,GUF1,JCHAIN,ZMYM2,CHPT1,LINC01913" MicroRNA hsa-miR-1202:mirSVR_lowEffct hsa-miR-1202:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-18 6.46E-15 7.24E-18 6.62E-17 68 1714 "RALGAPA1,KIAA1211,CUL4A,SNX24,ARHGAP5,ATP2B4,PROZ,NFATC4,CCNA1,NOVA1,CDKL2,MPZL1,RFLNA,CDK18,PDGFRA,ITGBL1,PIGR,POLN,HECTD1,EPGN,FCRL5,COG3,SUPT7L,C14orf119,B3GLCT,RNF31,RB1,OGFOD2,RGS12,CLIP4,SETDB2,EFNA5,LATS2,GRTP1,TBC1D19,ZNF219,ARSK,ETF1,TNFRSF19,RELL1,STAB2,SGCG,FSHR,LIMCH1,CYP1B1-AS1,GABRB1,KIF21B,NMNAT2,EAPP,NFASC,NPFFR2,LPIN1,ADGRL3,ANO4,RIPK3,ARHGEF28,DOCK9,TDG,NT5C1B,RIMBP2,CENPH,ZFHX2,ZNF324B,PLB1,ZBTB41,ZBED3-AS1,CHPT1,LETM1" MicroRNA hsa-miR-582-5p:PITA hsa-miR-582-5p:PITA_TOP PITA 1.24E-18 6.62E-15 7.40E-18 6.78E-17 38 544 "MAP1B,NDRG2,APC,STARD13,NOVA1,FCHO2,PDE4D,PGGT1B,STRN3,LYSMD3,DNM3,COG3,RASA1,RB1,ELF1,SAP18,MAEA,RELL1,FOXG1,FOXO1,FBXO11,PLEKHA6,NR5A2,CHFR,MYT1L,PDS5B,PSME4,TMED2,PPIP5K2,ADGRL3,XPO4,BAZ1A,RIMBP2,KLF12,HMGCR,SLAIN1,ZMYM2,ZBTB41" MicroRNA hsa-miR-554:mirSVR_lowEffct hsa-miR-554:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-18 6.62E-15 7.40E-18 6.78E-17 48 887 "TMEM132B,APAF1,WDR19,KCTD12,CARMIL3,PDGFRA,PFKFB2,CFAP54,C1orf116,RCHY1,GNPTAB,FAM169A,MPHOSPH8,NOS1AP,IFT172,FBXL5,WDR1,PARPBP,PPP2R3C,NR1H4,B3GLCT,LRPPRC,EFS,MAEA,ETF1,SULT6B1,FLT1,VEZT,G2E3,PLEKHA6,STPG4,MRPS14,NR5A2,KIF21B,CMPK2,IKBIP,ARHGEF28,DOCK9,TEP1,SLC7A8,GPR161,MZF1,CHPT1,KIF2A,KIF3C,LETM1,NUAK2,LMNB1" MicroRNA hsa-miR-497:mirSVR_highEffct hsa-miR-497:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.27E-18 6.74E-15 7.52E-18 6.88E-17 60 1365 "RGS5,ATP4B,MYBPC1,BCL2L2,PCDH9,CDK17,PDE4D,GLT1D1,GPR180,ITGBL1,CFAP54,CFAP45,JAKMIP1,THAP6,PREPL,IL20,LRRTM2,FCRL2,DCAF8,G3BP2,TMEM161B,CLIP4,LATS2,MBNL2,TBC1D19,DLEU1,ABCA11P,SPON2,FGF9,LRRN2,SUCO,FLT3,BRMS1L,IVNS1ABP,ARHGEF40,CCDC88A,SLC15A4,SLC22A4,MYT1L,NAAA,NPAS3,NFASC,DRC1,LRCH1,PCDH17,INSM2,RNF212,COP1,FZD10,GPN1,HTR2A,ANKS1B,ZMYM2,CHPT1,KIF2A,KIR2DS4,LINC01913,LCP1,RMST,SPRYD7" MicroRNA hsa-miR-3165:mirSVR_highEffct hsa-miR-3165:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-18 6.75E-15 7.52E-18 6.89E-17 36 483 "RALGAPA1,COG6,NCOA1,CD1D,PIGR,HECTD1,EPGN,VCAN,EIF2AK2,GLT8D2,ATG10,RGS12,TRAPPC12,SNORA53,KIRREL1,ADGRV1,SLC22A17,FNIP1,POLK,G2E3,NBEA,CGREF1,ACIN1,LIMCH1,CYP1B1-AS1,PPARGC1A,METAP2,GPR12,TCF7,HAL,HEXB,TPO,ADAMTS19,TMEM174,IL6ST,RNASE11" MicroRNA hsa-miR-429:PITA hsa-miR-429:PITA_TOP PITA 1.51E-18 8.02E-15 8.94E-18 8.18E-17 46 818 "MAP1B,MCC,CUL4A,MCFD2,APAF1,SLC4A4,STARD13,PPP1R12B,NEDD8,NOVA1,CDK17,CFL2,CHD1,ATAD2B,STRN3,LYSMD3,CRHBP,NCOR2,CSNK1G3,DCAF8,MATR3,CEP350,KLHL3,PARPBP,DNMT3A,ARGLU1,TMEM33,LATS2,CLIP1,FOXG1,SUPT20H,G2E3,BRMS1L,NR5A2,MEGF10,PDS5B,KDM3B,NFASC,PPARGC1A,KLF12,SLAIN1,NSD2,DCP2,SPTSSA,LHX9,TMEM178A" MicroRNA hsa-miR-622:mirSVR_highEffct hsa-miR-622:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-18 8.36E-15 9.30E-18 8.52E-17 45 783 "MDM4,KIAA1211,CDKL4,AACS,ATP2B4,DAOA,RILPL1,JAKMIP1,SNX17,PIGG,SREK1,PTGS2,NUDT12,TSEN15,RASA1,RB1,ELF1,CWC27,USP44,FGF9,POLK,SUCO,FOXG1,PEAR1,SELP,GOLGA2P5,SLC30A6,SLC22A4,CYP1B1-AS1,MYO16,MEGF10,CD244,ZBTB37,PPIP5K2,ANO4,EML4,CRB1,BAZ1A,RIMBP2,ATP6V0A2,HEXB,UBE2K,IL6ST,LINC00272,ZDHHC20" MicroRNA hsa-miR-491-5p:mirSVR_lowEffct hsa-miR-491-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-18 8.59E-15 9.54E-18 8.74E-17 71 1861 "ADD1,KIAA1211,SEMA6A,RGS5,ASTN1,ATP1A2,B4GALT3,MYH6,ARHGEF7,NOVA1,CHAMP1,PAH,ZNF664,CFL2,CPNE6,PIK3C2B,EPN1,FAM53A,NCOR2,SNCAIP,LRRTM2,CEP135,KIAA0040,FCRL5,SNX17,NUDT12,PTPRH,SACS,G3BP2,GNPDA2,PARPBP,ARGLU1,RGS12,TRIM28,ELK3,MARVELD2,EFS,F7,FCAR,TOMM40L,FNIP1,N4BP2L2,TNFRSF19,RELL1,PIBF1,SDC1,SLC34A2,SLC22A5,NR5A2,EFR3B,KIF21B,NAAA,IQGAP2,GJB2,ADGRA3,TFDP1,CRB1,LINC01551,IGSF8,TXK,STARD4,MZF1,IL6ST,GALP,ANKS1B,KCNJ9,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,LAD1" MicroRNA hsa-miR-1979:mirSVR_highEffct hsa-miR-1979:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-18 9.47E-15 1.05E-17 9.63E-17 48 895 "MDM4,CD1E,FAM177A1,SCFD2,CDK18,RGSL1,PDE4D,CFL2,PFKFB2,NRXN1,AKAP6,RCHY1,ITSN2,FCRL5,DMXL1,TINF2,TSEN15,NR1I3,PACRGL,RNASEL,TXNDC15,MARVELD2,EFS,ARSK,SUCO,VEZT,G2E3,C1orf112,MEGF10,GABRB1,UHRF1BP1L,HSPH1,CMPK2,MCCC2,PCDH17,MAST4,ZNF544,METAP2,GPR12,DOCK9,NCSTN,AP4S1,TMPO,ADAMTS19,CENPH,TTC41P,PABPN1,LOX" MicroRNA hsa-miR-548g:PITA hsa-miR-548g:PITA_TOP PITA 1.95E-18 1.04E-14 1.15E-17 1.05E-16 41 649 "ABL2,MAP1B,APAF1,ARHGAP5,NCOA1,SLC4A4,KCTD12,PCSK1,CENPC,ATAD2B,TAPT1,CLOCK,CSNK1G3,MATR3,SREK1,COG3,DHX9,G3BP2,GNPDA2,WDR1,TSEN15,DNMT3A,RASA1,CLIP4,LATS2,RELL1,SUCO,FBXO11,CCDC88A,CHFR,MYT1L,KDM5B,KDM3B,PCDH17,STRN,TMED2,DOCK9,BAZ1A,KLF12,NSD2,SPTSSA" MicroRNA hsa-miR-1200:mirSVR_highEffct hsa-miR-1200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.04E-18 1.09E-14 1.20E-17 1.10E-16 47 861 "NCOA1,CACNA1E,CD1E,PDE6B,CFAP45,POLN,THAP6,HOMER1,GNPTAB,CEP135,DNM3,FCRL5,ZFYVE16,SREK1,PTGS2,DMXL1,COCH,OCIAD1,TINF2,NR1H4,B3GLCT,ATG10,POLR1D,LATS2,RNF4,MPHOSPH9,TOMM40L,MROH9,FBXO11,BRMS1L,C1orf112,ZNF667,CHFR,RBKS,EML4,DOCK9,CRB1,ZBTB49,BAZ1A,IL25,ZNF470,SPTSSA,ZBED3-AS1,CHPT1,TTC41P,LAD1,RMST" MicroRNA hsa-miR-758:mirSVR_highEffct hsa-miR-758:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.05E-18 1.09E-14 1.21E-17 1.10E-16 44 753 "ADD1,FBRSL1,BLZF1,CAST,ZNF664,PCSK1,CFL2,UGT2B28,AKAP6,STRN3,VCAN,KIAA0040,DDX59,PTGS2,PXMP2,ELF1,DLEU1,TRAPPC13,PCBD2,GORAB,PIBF1,FLT3,RASA3,NBEA,ZNF605,FSHR,YPEL5,CHFR,RBKS,GJA3,MAST4,PSME4,STON1,EML4,TDG,CRB1,MAEL,NPL,GUF1,TADA2B,ZMYM2,NPHS2,ZBED3-AS1,CHPT1" MicroRNA hsa-miR-3144-3p:mirSVR_lowEffct hsa-miR-3144-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-18 1.17E-14 1.29E-17 1.18E-16 55 1173 "ADD1,FBRSL1,ARHGAP5,ZNF542P,CDKL2,LDB2,FAM177A1,PCSK1,CDK17,SMIM14,PREPL,SNCAIP,LACC1,CEP135,DNM3,ZFYVE16,MATR3,GNPDA2,PARPBP,RB1,FAM228A,LRPPRC,MBNL2,SPATA9,EFS,SH3YL1,FCAR,FGF9,TNFRSF19,FOXG1,PEAR1,FLT3,FBXO11,ZNF605,SLC12A2,CHFR,LIMCH1,CD244,MCCC2,GJA3,ADGRA3,XPO4,TFDP1,GPR161,MAEL,PAPPA2,ZNF470,ANKS1B,ZMYM2,ZBTB41,CHPT1,LMLN,KIF3C,EP400P1,SPRYD7" MicroRNA hsa-miR-3175:mirSVR_highEffct hsa-miR-3175:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.26E-18 1.20E-14 1.33E-17 1.21E-16 49 938 "NYNRIN,SEMA6A,CUL4A,ARL1,ATP2B4,B4GALT3,CARMIL3,FCRL3,NOVA1,NRL,CAST,CD1E,SCFD2,CDK18,RGSL1,ZNF595,NRXN1,PM20D1,VCAN,CEP135,NUDT12,PTPRH,GNPDA2,SLC9C2,LRPPRC,EFNA5,EFS,MAEA,PCGF3,CLIP1,SLC22A17,RELL1,POLK,FBXO11,SLC22A4,DCAF11,KDM5B,CD244,UHRF1BP1L,KDM3B,ZBTB37,STRN,MAST4,COP1,ADAMTS19,ZNF876P,NSD2,ZBED3-AS1,CDK2AP1" MicroRNA hsa-miR-548e:PITA hsa-miR-548e:PITA_TOP PITA 2.30E-18 1.22E-14 1.35E-17 1.24E-16 46 827 "MAP1B,MCC,SMIM15,TBC1D14,STXBP6,SLC4A4,KCTD12,ARHGEF7,BTF3,PCSK1,PDE4D,ATAD2B,BOD1L1,TAPT1,FAM53A,LYSMD3,CLOCK,DNM3,MPHOSPH8,MATR3,SREK1,COG3,G3BP2,B3GLCT,ETF1,PCGF3,FGFR3,SUCO,FBXO11,SLC8A1,CCDC88A,CHFR,MYT1L,PDS5B,ERBIN,STRN,MTUS2,DOCK9,XPO4,TDG,BAZ1A,NSD2,CENPH,SPTSSA,ZBTB41,KIF2A" MicroRNA hsa-miR-548d-3p:PITA hsa-miR-548d-3p:PITA_TOP PITA 2.38E-18 1.27E-14 1.40E-17 1.28E-16 43 721 "CUL4A,PITPNM2,APC,STARD13,ZNF664,PCDH9,XPR1,CFL2,NRXN1,ATAD2B,STRN3,BRI3BP,CSNK1G3,DCAF8,MTX3,ARGLU1,TRIM28,ETF1,SUCO,SDC1,FOXO1,ZCCHC8,NBEA,SCYL2,IVNS1ABP,CCDC88A,MYT1L,IQGAP2,KDM3B,SRP54,ERBIN,PCDH17,ATP11A,CNTN2,DOCK9,EMILIN1,BAZ1A,ADAMTS19,HSP90B1,SPTSSA,ZMYM2,ZBTB41,PABPN1" MicroRNA hsa-miR-548a-3p:PITA hsa-miR-548a-3p:PITA_TOP PITA 2.41E-18 1.28E-14 1.41E-17 1.29E-16 46 828 "MAP1B,MCC,SMIM15,TBC1D14,STXBP6,SLC4A4,KCTD12,ARHGEF7,BTF3,PCSK1,PDE4D,BOD1L1,TAPT1,FAM53A,LYSMD3,CLOCK,DNM3,MPHOSPH8,MATR3,SREK1,COG3,G3BP2,B3GLCT,ETF1,PCGF3,FGFR3,SUCO,FBXO11,SLC8A1,CCDC88A,CHFR,MYT1L,GABRB1,PDS5B,ERBIN,STRN,MTUS2,DOCK9,XPO4,TDG,BAZ1A,NSD2,CENPH,SPTSSA,ZBTB41,KIF2A" MicroRNA hsa-miR-188-5p:mirSVR_highEffct hsa-miR-188-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-18 1.29E-14 1.42E-17 1.30E-16 45 792 "SMIM15,BIRC6,MCFD2,BLZF1,ATP2B4,ARHGEF7,AMDHD1,ODC1,PCDH9,PDE4D,LACC1,MATR3,COG3,FBXL5,RABGAP1L,TSEN15,ATG10,RASA1,LATS2,DCUN1D2,STX2,GORAB,FNIP1,SUCO,NBEA,TADA1,CCDC88A,YPEL5,MYT1L,NPAS3,MRPS27,KLHL20,MIMT1,INSM2,PPIP5K2,CRB1,TMPO,HAL,GPN1,SLAIN1,PAPPA2,STARD4,ZMYM2,CHPT1,LMNB1" MicroRNA hsa-miR-575:mirSVR_highEffct hsa-miR-575:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-18 1.30E-14 1.43E-17 1.31E-16 42 687 "SMIM15,COG6,ATP7B,SLC5A8,DCLK1,PCK2,CFL2,SMIM14,PIK3C2B,BOD1L1,CSNK1G3,BIVM,SREK1,DMXL1,SACS,GNPDA2,C14orf119,DTD2,RGS12,CWC27,TOMM40L,POLK,SELP,MROH9,FMO1,ZNF667,YPEL5,GABRA2,HSPH1,MAST4,ANO4,EML4,VRK2,YTHDC2,ZNF10,ZAR1L,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,RMST" MicroRNA hsa-miR-27b*:mirSVR_lowEffct hsa-miR-27b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.74E-18 1.46E-14 1.60E-17 1.46E-16 58 1303 "MAP1B,ADD1,ARL1,SLC4A4,BCL2L2,ARHGEF7,NOVA1,NRL,PDGFRA,ZNF595,MRPL57,SMIM14,HOMER1,STRN3,ITSN2,PSME1,PTPRC,OCIAD1,GNPDA2,PARPBP,SMC6,MARVELD2,FCAMR,ABCA11P,GMPR2,FLT1,FBXO11,NBEA,ZNF605,DCAF11,MYO16,GABRA2,EAPP,NPAS3,RBKS,MCCC2,LPIN1,ZNF544,ADAM17,ARHGEF28,C1QTNF9B,COX18,NCSTN,CRB1,AP4S1,RASSF6,RAB2B,RIMBP2,HMGCR,GUF1,HSD17B4,KCNT2,ANKS1B,ZBTB41,EP400P1,NUAK2,LMNB1,PABPN1" MicroRNA hsa-miR-93-5p:Functional MTI Functional MTI miRTarbase 2.76E-18 1.47E-14 1.61E-17 1.47E-16 56 1220 "MCC,ADD1,ULK1,APBB2,ARL1,PPP1R12B,BCL2L2,ARHGEF7,NFKBIA,FCHO2,CFL2,PFKFB2,POLE,GNPTAB,LYSMD3,CLOCK,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,SACS,RABGAP1L,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,LATS2,ETF1,DNAJC27,N4BP2L2,SUCO,BRMS1L,ZNF446,ACIN1,GAK,EAPP,ERAP1,KDM3B,KLHL20,ZBTB37,GRSF1,GTF2H3,TXK,UBC,NSD2,TADA2B,IRF1,ZBTB41,ZDHHC20" MicroRNA hsa-miR-137:TargetScan hsa-miR-137 TargetScan 2.80E-18 1.49E-14 1.63E-17 1.49E-16 49 943 "CUL4A,PITPNM2,BLZF1,ARHGAP5,AACS,NCOA1,KCTD12,NOVA1,CAMK4,PDE4D,PDGFRA,CFL2,CHD1,GPR180,NRXN1,HOMER1,BRI3BP,CSNK1G3,DCAF8,DMXL1,KLHL3,NR1H4,DNMT3A,LATS2,RNF4,SBNO1,MBNL2,FAM172A,ARSK,FNIP1,FGF9,NBEA,LIMCH1,MYT1L,KDM5B,NPAS3,NFASC,LRCH1,PPARGC1A,ATP11A,MTUS2,GOLGA3,ANO4,ACSL6,BAZ1A,KLF12,SDR39U1,KIT,FAM71C" MicroRNA hsa-miR-502-5p:mirSVR_highEffct hsa-miR-502-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-18 1.49E-14 1.63E-17 1.49E-16 47 868 "SEMA6A,ATP1A2,SLC4A4,ZNF542P,B4GALT3,STARD13,CDKL2,CAST,UHMK1,RGSL1,PFKFB2,ZNF595,THAP6,NCOR2,SNCAIP,ZFYVE16,MATR3,TINF2,SACS,SUPT7L,RASA1,SLC9C2,FAM172A,DLEU1,GMPR2,PCBD2,TNFRSF19,HSD17B7,VEZT,NUBPL,SLC15A4,NAAA,NFASC,METAP2,ADGRL3,ANO4,TFDP1,TGM1,ADAMTS19,GPN1,SLAIN1,IGF1,CCDC169,PLB1,KCNN2,ANKDD1B,AXDND1" MicroRNA hsa-miR-22:mirSVR_lowEffct hsa-miR-22:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-18 1.55E-14 1.69E-17 1.55E-16 66 1653 "MAP1B,SMIM15,ADD1,ADORA1,ULK1,ARL1,ASCL1,NCOA1,BTF3,PCDH9,ITGBL1,LTB4R,HECTD1,AKAP6,HEATR5A,CRHBP,SNCAIP,BRI3BP,GALNT9,KIAA0040,ZFYVE16,DGKQ,DMXL1,CEP350,RABGAP1L,AASDH,RGS12,LRPPRC,EFNA5,MPHOSPH9,MARVELD2,FAM172A,CWC27,MAEA,ETF1,TRAPPC13,FCAR,RELL1,TACC3,SUCO,FLT1,DDX51,PLEKHA6,ARHGEF40,CGREF1,LIMCH1,CD244,CMPK2,RBKS,ZNF544,ANO4,EML4,DOCK9,KHNYN,COP1,NT5C1B,SLC7A8,ZBTB49,ADAMTS19,UBE2K,ARHGAP30,IGF1,IL6ST,PLB1,LIG4,SKA3" MicroRNA hsa-miR-548l:PITA hsa-miR-548l:PITA_TOP PITA 3.01E-18 1.60E-14 1.75E-17 1.60E-16 41 657 "CUL4A,EP400,APC,ARHGAP5,ASCL1,NOVA1,FAM177A1,CFL2,STRN3,CSNK1G3,DNM3,COG3,DMXL1,CEP350,SACS,G3BP2,RASA1,LATS2,FAM172A,ETF1,USP44,FNIP1,ZCCHC8,RUBCNL,G2E3,NBEA,IVNS1ABP,NR5A2,KDM3B,GJA3,METAP2,TCF7,EML4,RIMBP2,KLF12,UBE2K,HMGCR,SLAIN1,ZNF470,ZBTB41,LHX9" MicroRNA hsa-miR-122:mirSVR_lowEffct hsa-miR-122:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.03E-18 1.61E-14 1.75E-17 1.61E-16 57 1264 "RALGAPA1,MAP1B,BIRC6,NLN,SLAMF6,MIPEP,RGS5,MSH2,WDR19,CENPBD1P1,ATP1A2,KCTD12,MYH7,CDKL2,TAF1B,SNTG2,XPR1,CHD1,CCDC122,SNX6,LYSMD3,COG3,CEP350,G3BP2,EGLN3,AASDH,CLIP4,ZNF419,NTN4,PACRGL,LGR6,FCAMR,FAM172A,FLT1,C1orf112,SLC22A4,NMNAT2,LILRB1,PCDH17,GJA3,UTP20,ADAM17,RIPK3,ZBTB49,LINC01551,RIMBP2,HSP90B1,GPN1,RXFP2,MZF1,ZBTB41,NPHS2,KIR2DL4,KIR2DS4,NUAK2,AXDND1,MICU2" MicroRNA hsa-miR-1275:mirSVR_lowEffct hsa-miR-1275:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-18 1.62E-14 1.76E-17 1.61E-16 70 1837 "SFTA3,MCC,LRRC43,WDR35,SEMA6A,HOMEZ,MCFD2,ARHGAP5,NOP14,AACS,NCOA1,FGFRL1,CBLN3,FCGR2C,CDK18,CENPC,LTB4R,LYSMD3,ITSN2,FAM169A,DNM3,EIF2AK2,ZNF586,SNX17,EPS8L1,DCT,PTPRC,NR1H4,RASA1,AASDH,RGS12,CLIP4,EFNA5,EFS,PCGF3,F7,SUCO,PEAR1,HSD17B7,FTLP10,ZNF446,SLC8A1,ZNF605,PKD2L2,CGREF1,EFR3B,GABRA2,RAPGEF6,UHRF1BP1L,MRPS27,PPIP5K2,ANO4,GPR12,TCF7,RIPK3,STON1,C1QTNF9B,EMILIN1,SLC7A8,LINC01551,RAB2B,RIMBP2,KLF12,GPN1,NSD2,IGF1,CCDC169,MFSD2B,LINC01913,LETM1" MicroRNA hsa-miR-613:mirSVR_highEffct hsa-miR-613:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.13E-18 1.66E-14 1.81E-17 1.66E-16 52 1062 "RALGAPA1,BIRC6,ANKRD34B,DDX55,PNP,DAOA,TAF1B,CAST,PDGFRA,SMIM14,ZNF586,MATR3,EPS8L1,COCH,OCIAD1,GNPDA2,DHFR,WDR1,NR1H4,RASA1,AASDH,DTD2,EIF2D,ADGRV1,PIBF1,NBEA,UFM1,SLC8A1,CD244,NPAS3,LRCH1,PCDH17,PPARGC1A,ADGRA3,ANO4,YIPF7,COX18,LINC01551,NPL,HSP90B1,HMGCR,ZNF550,IGF1,ZNF140,ZMYM2,LHX9,FAM151B,TMEM178A,KIF2A,KIF3C,AXDND1,EEF1AKMT1" MicroRNA hsa-miR-634:mirSVR_lowEffct hsa-miR-634:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.24E-18 1.72E-14 1.87E-17 1.71E-16 63 1523 "MDM4,NDRG2,KIAA1211,ARL1,ATP2B4,CADM3,NFKBIA,LINC02347,NOVA1,DAOA,CACNA1E,SNTG2,SCFD2,PDGFRA,PFKFB2,HECTD1,PTPRVP,IL20,CEP135,DNM3,NOS1AP,DCAF8,IFT172,COG3,DMXL1,OCIAD1,LINC01257,TMEM161B,REST,TMEM33,CLIP4,STX2,ZNF219,DNAJC27,ADGRV1,N4BP2L2,FGFR3,FBXO11,SLC8A1,ARHGEF40,C1orf112,EFR3B,RAPGEF6,NFASC,DRC1,PCDH17,ZNF544,ADAM17,ADGRL3,C5orf56,NCSTN,TFDP1,SLC7A8,ATP6V0A2,ADAMTS19,HMGCR,TECRL,WDR36,ZNF470,PLB1,KCNN2,LAD1,AXDND1" MicroRNA hsa-miR-4314:mirSVR_highEffct hsa-miR-4314:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.29E-18 1.75E-14 1.90E-17 1.74E-16 51 1024 "RGS5,APAF1,BCL2L2,TAF1B,CAST,SLC5A8,PCSK1,RGSL1,CHIT1,LINC01085,PIK3C2B,BRI3BP,UBXN2A,FCRL5,DCAF8,SNX17,BIVM,FBXL5,NR1I3,OGFOD2,RGS12,PACRGL,RNASEL,KIRREL1,LGR6,STX2,ABCA11P,TOMM40L,FGF9,PIBF1,FLT1,PAICS,CCDC88A,C1orf112,SLC22A4,CYP1B1-AS1,GABRA2,GABRB1,PDS5B,RAPGEF6,CMPK2,TGFBI,LINC01551,AP4S1,ZNF721,ADAMTS19,ZNF26,PLB1,KIR2DL4,NUAK2,IFT88" MicroRNA hsa-miR-411:mirSVR_lowEffct hsa-miR-411:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.74E-18 1.99E-14 2.16E-17 1.98E-16 57 1270 "MAP1B,MATN3,BIRC6,COG6,APC,WDR19,ARHGAP5,ATP1A2,ATP2B4,NFATC4,DAOA,MPZL1,CDK17,CFAP45,SNCAIP,ITSN2,CEP135,BIVM,PTPRC,PTPRH,RABGAP1L,TSEN15,EGLN3,FAM129A,SETDB2,DHRS2,FAM172A,DRAM1,CLIP1,FCAR,FGF9,POLK,FOXG1,FLT1,FLT3,IVNS1ABP,SLC22A5,YPEL5,PDS5B,RAPGEF6,IKBIP,CFHR4,NPFFR2,MAST4,ATP11A,SCFD1,COX7B2,ACSL6,COX18,HSD17B4,PAPPA2,STARD4,ZNF10,SPTSSA,LHX9,KIF2A,RNASE11" MicroRNA hsa-miR-2114*:mirSVR_lowEffct hsa-miR-2114*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.75E-18 1.99E-14 2.16E-17 1.98E-16 58 1312 "KIAA1211,SLAMF6,ADCY4,DHX37,DDX55,PPP1R12B,FGFRL1,LINC02347,CBLN3,CDKL2,SCARB1,PCDH9,ZMYM5,RGSL1,PDE4D,CHIT1,COLEC11,LRRTM2,FAM169A,ZNF586,EPS8L1,LINC01257,RNF219,B3GLCT,RGS4,RGS12,MEMO1,GRTP1,DRAM1,STK32B,GMPR2,N4BP2L2,LRRN2,TM9SF1,SLC34A2,CGREF1,WDCP,SLC22A4,PDS5B,TMEM183A,UHRF1BP1L,MRPS27,KDM3B,CMPK2,NFASC,DRC1,METAP2,CNTN2,RIPK3,ARHGEF28,STON1,POC5,NSD2,PLB1,ZMYM2,LINC00272,EP400P1,NUAK2" MicroRNA hsa-miR-149*:mirSVR_highEffct hsa-miR-149*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.77E-18 2.00E-14 2.17E-17 1.98E-16 49 950 "ARHGEF7,CBLN3,CDK18,WDR66,RGSL1,CHD1,CPNE6,PIK3C2B,AKAP6,THTPA,WDR1,DNMT3A,RGS12,GUSBP3,RNASEL,SNORA49,LGR6,GMPR2,SLC22A17,FNIP1,RELL1,FOXG1,ZCCHC8,SLC34A2,TMEM132D,ZNF667,ACIN1,MYO16,KIF21B,KDM5B,JPH4,NAAA,ATP8A2,MRPS27,KDM3B,NFASC,COMMD6,LINC02393,SPIC,ANO4,KMT5A,SLC7A8,BAZ1A,ACTR6,RAB2B,FZD10,IGSF8,NSD2,CAB39L" MicroRNA hsa-miR-891b:mirSVR_highEffct hsa-miR-891b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.92E-18 2.09E-14 2.25E-17 2.06E-16 48 913 "WDR35,RILPL1,LDB2,PCK2,SCFD2,CDK17,CEBPE,PDGFRA,UGT2B28,AKAP6,TAPT1,SNX17,COG3,DMXL1,PTPRC,PARPBP,TSEN15,DNMT3A,RAN,ARGLU1,TMEM161B,UGT2A3,BORA,DEPDC4,ARSK,DLEU1,ABCA11P,GORAB,SUCO,SUPT20H,TM9SF1,UFM1,GFM2,IVNS1ABP,CCDC88A,SNRPF,MYT1L,GABRB1,NMNAT2,MAST4,ANO4,EML4,COX18,RNF17,JCHAIN,ZMYM2,RMST,LIG4" MicroRNA hsa-miR-378c:mirSVR_lowEffct hsa-miR-378c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.07E-18 2.16E-14 2.33E-17 2.14E-16 71 1894 "ADORA1,ANKRD34B,FAM193A,CENPBD1P1,NFATC4,CCNA1,LINC02347,RAB29,NOVA1,MPZL1,SNTG2,ZNF664,PCDH9,DCLK1,CDK7,PCSK1,CDK18,WDFY2,MRPL57,AKAP6,CLOCK,SNCAIP,UBXN2A,DHFR,NR1H4,FAM129A,RNF31,RB1,ZNF419,SETDB2,CWC27,ABCA11P,FCGR3B,TACC3,SUCO,PEAR1,SH3BP2,DDX51,PAICS,ZNF446,STPG4,ARHGEF40,WDCP,ACIN1,NMNAT2,RAPGEF6,UHRF1BP1L,NFASC,MCCC2,IKBIP,GJA3,ZNF544,ANO4,TCF7,TEP1,GRSF1,BAZ1A,RAB2B,ATP6V0A2,TMEM174,KCNT2,ZNF324B,CCDC169,PLB1,ANKS1B,LHX9,EP400P1,RNASE11,LETM1,RMST,LMNB1" MicroRNA hsa-miR-424*:mirSVR_highEffct hsa-miR-424*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.30E-18 2.28E-14 2.46E-17 2.25E-16 40 630 "SMIM15,COG6,SNX24,SLC4A4,KCTD12,PDGFRA,NRXN1,SNX6,GNPTAB,CEP135,ZNF586,PTGS2,DMXL1,NUDT12,F11R,GALNT14,NTN4,RNASEL,LATS2,ELK3,STX2,DNAJC27,GORAB,SUCO,FOXG1,VEZT,UGGT2,NAAA,ANKLE2,LRCH1,SULT1E1,ADAM17,METAP2,MTUS2,MAEL,YTHDC2,SPTSSA,ZBTB41,CHPT1,RMST" MicroRNA hsa-miR-215:mirSVR_lowEffct hsa-miR-215:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.65E-18 2.47E-14 2.66E-17 2.44E-16 49 955 "SFTA3,MIPEP,ATP1A2,NOVA1,ZMYM5,ATAD2B,PTPRVP,HOMER1,TAPT1,RCHY1,VCAN,NOS1AP,FCRL2,DCAF8,BIVM,COG3,PTGS2,DHFR,RNF219,FAM129A,CLIP4,RNASEL,PCGF3,TOMM40L,FOXG1,FLT1,G2E3,NUBPL,POTEM,WDCP,ZNF667,UGGT2,MEGF10,GABRA2,NMNAT2,ATP8A2,ANKLE2,TCF7,EML4,COX18,CRB1,TXK,STARD4,IGF1,IL6ST,ANKS1B,LMLN,LINC01913,SPRYD7" MicroRNA hsa-miR-192:mirSVR_lowEffct hsa-miR-192:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.65E-18 2.47E-14 2.66E-17 2.44E-16 49 955 "SFTA3,MIPEP,ATP1A2,NOVA1,ZMYM5,ATAD2B,PTPRVP,HOMER1,TAPT1,RCHY1,VCAN,NOS1AP,FCRL2,DCAF8,BIVM,COG3,PTGS2,DHFR,RNF219,FAM129A,CLIP4,RNASEL,PCGF3,TOMM40L,FOXG1,FLT1,G2E3,NUBPL,POTEM,WDCP,ZNF667,UGGT2,MEGF10,GABRA2,NMNAT2,ATP8A2,ANKLE2,TCF7,EML4,COX18,CRB1,TXK,STARD4,IGF1,IL6ST,ANKS1B,LMLN,LINC01913,SPRYD7" MicroRNA hsa-miR-34b*:mirSVR_highEffct hsa-miR-34b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.82E-18 2.56E-14 2.75E-17 2.52E-16 52 1073 "MDM4,NLN,SLAMF6,STXBP6,ASCL1,TAF1B,SLC5A8,DCLK1,PDGFRA,CENPC,CHD1,CFAP54,TM9SF2,SMIM14,ATAD2B,JAKMIP1,HECTD1,EPGN,PREPL,ZNF586,SPATA18,SREK1,COG3,KLHL3,RABGAP1L,NR1H4,SMC6,RGS4,MARVELD2,POLK,HSD17B7,G2E3,MYO16,GABRA2,IQGAP2,NPAS3,CMPK2,RBKS,ERBIN,PSME4,MTUS2,TGFBI,GTF3C2,RIMBP2,ATP6V0A2,WDR36,NSD2,FCRL6,MZF1,SPTSSA,ANKS1B,LCP1" MicroRNA hsa-miR-520f:mirSVR_highEffct hsa-miR-520f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.09E-18 2.70E-14 2.90E-17 2.66E-16 56 1237 "COG6,BTF3,NOVA1,PCDH9,CFL2,RCBTB2,THAP6,AKAP6,LYSMD3,C12orf65,LRRTM2,SREK1,CEP350,COCH,GNPDA2,WDR1,RNF219,FAM129A,B3GLCT,RGS12,CLIP4,NTN4,PACRGL,MBNL2,MPHOSPH9,DEPDC4,DNAJC27,IRF9,TNFRSF19,POLK,HSD17B7,FBXO11,DDX51,PKD2L2,YPEL5,PDS5B,ERAP1,IKBIP,ZBTB37,STRN,COX7B2,PPIP5K2,MTUS2,ADGRL3,TGFBI,BAZ1A,ARHGAP30,TXK,C12orf73,IL6ST,AXDND1,ZDHHC20,LIG4,LMNB1,IFT88,LOX" MicroRNA hsa-miR-525-5p:mirSVR_highEffct hsa-miR-525-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.14E-18 2.73E-14 2.93E-17 2.68E-16 50 996 "SLC4A4,NOVA1,SLC5A8,CFL2,CHD1,PFKFB2,SNX6,THAP6,NGDN,CSNK1G3,ITSN2,LRRTM2,DCAF8,TINF2,GNPDA2,NR1H4,EGLN3,RB1,RGS4,ELOVL7,USP44,FCGR3A,UTP15,FCGR3B,PIBF1,HSD17B7,STAB2,FBXO11,ALKAL2,ZNF605,SLC22A4,PDS5B,UHRF1BP1L,IQGAP2,MRPS27,MAST4,INSM2,ADAM17,CRB1,TMPO,HEXB,GUF1,SLAIN1,IGF1,PLB1,ZMYM2,KIF2A,ZDHHC20,LMNB1,PABPN1" MicroRNA hsa-miR-1274a:mirSVR_lowEffct hsa-miR-1274a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.19E-18 2.76E-14 2.96E-17 2.71E-16 59 1364 "ADD1,KIAA1211,NYNRIN,DHX37,APC,AACS,CENPBD1P1,NLRP4,B4GALT3,CD1E,CDK18,PDGFRA,GLT1D1,THAP6,THTPA,EPGN,NCOR2,SNCAIP,LRRTM2,EIF2AK2,DMXL1,RABGAP1L,DHFR,SUPT7L,SLC35F6,PARPBP,TSEN15,DTD2,RGS12,ARSK,ADGRV1,SLC22A17,FCGR2B,PAICS,UFM1,MYT1L,NMNAT2,ERAP1,NPAS3,ERBIN,LILRB1,PCDH17,STRN,ADAM17,METAP2,C5orf56,TCF7,STON1,CRB1,GPR161,GPN1,ARHGAP30,DCP2,ZNF140,IRF1,LINC00272,LHX9,KIR2DL4,LAD1" MicroRNA hsa-miR-4280:mirSVR_highEffct hsa-miR-4280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.40E-18 2.87E-14 3.07E-17 2.81E-16 39 601 "STXBP6,ASTN1,ATP4B,ARHGEF7,TAF1B,SLC5A8,PDE4D,PDGFRA,LINC01085,THAP6,AKAP6,POLE,CSNK1G3,UBXN2A,TINF2,NTN4,LRPPRC,RNASEL,GRTP1,KLHL12,DHRS2,ARSK,ETF1,SH3YL1,UTP15,FLT1,BRMS1L,CCDC88A,MYO16,GJA3,TMED2,ADGRL3,ADGRA3,C5orf56,HSD17B4,YTHDC2,ANKS1B,ZBTB41,KCNN2" MicroRNA hsa-miR-378b:mirSVR_highEffct hsa-miR-378b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.70E-18 3.03E-14 3.24E-17 2.96E-16 41 669 "SNX24,BCL2L2,ARHGEF7,DAOA,NRL,CHAMP1,SLC5A8,PCCA,CHIT1,ZNF595,GPR180,TM9SF2,PIK3C2B,ATAD2B,TINF2,RNF219,IPO4,CLIP4,POLR1D,FCGR3A,FOXG1,MROH9,FLT1,VEZT,SLC34A2,MBIP,IVNS1ABP,GABRB1,ERAP1,MRPS27,GZMB,FZD10,UBE2K,GPN1,ZNF876P,VRK2,IL6ST,KIF2A,SLAMF9,NUAK2,SPRYD7" MicroRNA hsa-miR-367-3p:TargetScan hsa-miR-367-3p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-32-5p:TargetScan hsa-miR-32-5p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-25-3p:TargetScan hsa-miR-25-3p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-92a-3p:TargetScan hsa-miR-92a-3p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-363-3p:TargetScan hsa-miR-363-3p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-92b-3p:TargetScan hsa-miR-92b-3p TargetScan 6.27E-18 3.33E-14 3.54E-17 3.24E-16 44 776 "ABL2,MAP1B,KIAA1211,PITPNM2,NCOA1,ASTN1,ATP2B4,NOVA1,GAS2L3,FCHO2,CFL2,GPR180,DCAF8,DMXL1,CEP350,KLHL3,G3BP2,RABGAP1L,DNMT3A,REST,CLIP4,LATS2,RNF4,SBNO1,DNAJC27,PCGF3,FNIP1,POLK,FOXG1,BRMS1L,PLEKHA6,N4BP2,EFR3B,MYT1L,PDS5B,IQGAP2,NPAS3,LRCH1,ATP11A,PPIP5K2,GOLGA3,ANO4,DOCK9,FZD10" MicroRNA hsa-miR-200c:PITA hsa-miR-200c:PITA_TOP PITA 7.14E-18 3.80E-14 4.02E-17 3.68E-16 45 815 "MAP1B,MCC,CUL4A,MCFD2,APAF1,SLC4A4,STARD13,PPP1R12B,NEDD8,NOVA1,CDK17,CFL2,CHD1,ATAD2B,STRN3,LYSMD3,CRHBP,NCOR2,CSNK1G3,DCAF8,MATR3,CEP350,KLHL3,PARPBP,DNMT3A,ARGLU1,TMEM33,LATS2,CLIP1,FOXG1,SUPT20H,G2E3,BRMS1L,NR5A2,MEGF10,PDS5B,KDM3B,NFASC,PPARGC1A,KLF12,NSD2,DCP2,SPTSSA,LHX9,TMEM178A" MicroRNA hsa-miR-200b:PITA hsa-miR-200b:PITA_TOP PITA 7.14E-18 3.80E-14 4.02E-17 3.68E-16 45 815 "MAP1B,MCC,CUL4A,MCFD2,APAF1,SLC4A4,STARD13,PPP1R12B,NEDD8,NOVA1,CDK17,CFL2,CHD1,ATAD2B,STRN3,LYSMD3,CRHBP,NCOR2,CSNK1G3,DCAF8,MATR3,CEP350,KLHL3,PARPBP,DNMT3A,ARGLU1,TMEM33,LATS2,CLIP1,FOXG1,SUPT20H,G2E3,BRMS1L,NR5A2,MEGF10,PDS5B,KDM3B,NFASC,PPARGC1A,KLF12,NSD2,DCP2,SPTSSA,LHX9,TMEM178A" MicroRNA hsa-miR-517*:mirSVR_highEffct hsa-miR-517*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.23E-18 3.84E-14 4.07E-17 3.73E-16 44 779 "MDM4,NDRG2,NLN,ANKRD34B,CUL4A,UVSSA,LINC02347,LDB2,SLC5A8,CENPC,HOMER1,RNASE9,LACC1,TTC37,VCAN,NUDT12,PTPRC,SACS,TSEN15,RASA1,TRAPPC12,LGR6,ARSK,CWC27,DNAJC27,ABCA11P,FGFR3,UFM1,PKD2L2,SLC22A4,JPH4,RAPGEF6,OXGR1,NPAS3,NPFFR2,BRD8,GPR161,RIMBP2,ZNF721,ADAMTS19,ARHGAP30,KIR2DL4,LCP1,AXDND1" MicroRNA hsa-miR-3185:mirSVR_highEffct hsa-miR-3185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.27E-18 3.87E-14 4.08E-17 3.74E-16 57 1289 "RALGAPA1,ABL2,IL17D,LRRC43,ANKRD34B,MCFD2,FBRSL1,STARD13,PPP1R12B,CD84,CCNA1,PCSK1,PFKFB2,NRXN1,SNX6,HOMER1,STRN3,CSNK1G3,SNX17,SPATA18,PIGG,GNPDA2,TBC1D19,ARSK,SLC22A17,FCGR3B,STAB2,NBEA,CCDC92,NUBPL,IVNS1ABP,WDCP,MRPS14,CHFR,KDM5B,JPH4,CD244,NPAS3,SRP72,PCDH17,SULT1E1,LINC02393,ANO4,EML4,TMPO,FZD10,TNR,TMEM174,NLRP8,TPTE2,CCDC169,TMEM178A,RNASE11,LCP1,LMNB1,PABPN1,LTA4H" MicroRNA hsa-miR-888:PITA hsa-miR-888:PITA_TOP PITA 7.27E-18 3.87E-14 4.08E-17 3.74E-16 33 420 "MAP1B,SLC4A4,ATP2B4,KCTD12,PPP1R12B,WDFY2,GPR180,SMIM14,ATAD2B,DNM3,G3BP2,RGS4,LATS2,MBNL2,PCGF3,FNIP1,FOXG1,SUPT20H,SFSWAP,ALKAL2,IVNS1ABP,NR5A2,NMNAT2,PCDH17,PPARGC1A,GJA3,ADGRL3,XPO4,BAZ1A,UBE2K,SPTSSA,ZMYM2,PABPN1" MicroRNA hsa-miR-520b:mirSVR_highEffct hsa-miR-520b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.44E-18 3.96E-14 4.17E-17 3.82E-16 58 1332 "MDM4,BIRC6,KIAA1211,B4GALT3,CCNA1,MORN2,FCRLB,RFLNA,PCDH9,FAM177A1,RGSL1,CFL2,PGGT1B,JAKMIP1,THAP6,POU2F1,LYSMD3,CRHBP,C12orf65,ITSN2,CEP135,DCAF8,SPATA18,NUDT12,GNPDA2,IPO4,CLIP4,NTN4,RNASEL,LATS2,MPHOSPH9,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,HSD17B7,VEZT,FBXO11,BRMS1L,SLC30A6,ARHGEF40,YPEL5,MYT1L,ZBTB37,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,TEP1,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-3183:mirSVR_highEffct hsa-miR-3183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.48E-18 3.98E-14 4.19E-17 3.84E-16 45 816 "HOMEZ,FAM193A,PPP1R12B,ARHGEF7,PNP,CDKL2,CD1D,TSSK4,ITGBL1,NRXN1,PIK3C2B,ATAD2B,LACC1,GALNT9,RABGAP1L,NR1H4,DNMT3A,DTD2,CLIP4,GUSBP3,CWC27,FCGR2B,FTLP10,SUPT20H,VEZT,ZCCHC8,SLC22A4,LIMCH1,GABRB1,ZBTB37,BRD8,MAST4,METAP2,ADGRA3,C5orf56,C1QTNF9B,TGFBI,STARD4,ZNF26,IGF1,ZNF470,ANKS1B,KCNN2,AXDND1,PABPN1" MicroRNA hsa-miR-135b*:mirSVR_lowEffct hsa-miR-135b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.67E-18 4.08E-14 4.30E-17 3.93E-16 52 1085 "TMEM132B,ADD1,ADORA1,NYNRIN,MIPEP,SEMA6A,BLZF1,ARL1,ASCL1,CENPBD1P1,STARD13,ARHGEF7,ZNF664,CHD1,THAP6,SNCAIP,CSNK1G3,ITSN2,CMTM5,DCAF8,PIGG,CEP350,KLHL3,RB1,SETDB2,EIF2D,EFNA5,MBNL2,LGR6,MARVELD2,ARSK,CWC27,ABCA11P,TRAPPC13,FCGR3B,TNFRSF19,PIBF1,HSD17B7,STAB2,ZCCHC8,P2RX2,CYP1B1-AS1,GJA3,MTUS2,CRB1,MSH6,ZNF721,GPN1,PAPPA2,EP400P1,LCP1,ZNF304" MicroRNA hsa-miR-520e:mirSVR_highEffct hsa-miR-520e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.69E-18 4.09E-14 4.30E-17 3.94E-16 58 1333 "MDM4,KIAA1211,B4GALT3,CCNA1,MORN2,CD1E,FCRLB,RFLNA,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,NRXN1,JAKMIP1,THAP6,LYSMD3,CRHBP,SNCAIP,C12orf65,ITSN2,CEP135,GNPDA2,CLIP4,NTN4,RNASEL,LATS2,MPHOSPH9,DRAM1,DNAJC27,TRAPPC13,IRF9,RELL1,PIBF1,POLK,SUCO,HSD17B7,VEZT,ZCCHC8,FBXO11,BRMS1L,ARHGEF40,YPEL5,MYT1L,CENPJ,ZBTB37,INSM2,PPIP5K2,MTUS2,ADGRL3,GPR12,KMT5C,EMILIN1,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88" MicroRNA hsa-miR-568:PITA hsa-miR-568:PITA_TOP PITA 8.21E-18 4.36E-14 4.58E-17 4.20E-16 36 512 "SFTA3,MCC,ARHGAP5,ASCL1,SLC4A4,KCTD12,BTF3,UHMK1,PDGFRA,ZNF595,WDFY2,BOD1L1,STRN3,LYSMD3,CSNK1G3,MATR3,COG3,CLIP4,USP44,RELL1,FOXO1,SUPT20H,NBEA,PLEKHA6,ALKAL2,PDS5B,KLHL20,PPARGC1A,GJA3,EML4,RIMBP2,ADAMTS19,DCP2,IGF1,IRF1,ZBTB41" MicroRNA hsa-miR-24-3p:Functional MTI Functional MTI miRTarbase 8.24E-18 4.38E-14 4.60E-17 4.21E-16 46 855 "MDM4,ADD1,TBC1D14,APAF1,ARL1,NOP14,BCL2L2,ARHGEF7,SLC5A6,NFKBIA,TAF1B,RILPL1,CCNB1,PCK2,FAM177A1,PDE6B,CCDC122,WDFY2,PIGR,STRN3,LRRTM2,MATR3,DHFR,DTD2,TMEM33,ARSK,CWC27,FGFR3,TACC3,BRMS1L,NUBPL,CHFR,UHRF1BP1L,BRD8,ADAM17,METAP2,KHNYN,COP1,NCSTN,GTF3C2,ATP6V0A2,UBE2K,UBC,DCP2,IGF1,ZDHHC20" MicroRNA hsa-miR-1227:mirSVR_lowEffct hsa-miR-1227:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.90E-18 4.73E-14 4.96E-17 4.54E-16 61 1467 "RALGAPA1,MDM4,ADD1,NYNRIN,APBB2,CDKL4,ARHGAP5,NOP14,ATP1A2,CD84,LINC02347,ZMYM5,CDK18,CFL2,CPNE6,AKAP6,HEATR5A,CRHBP,SPATA18,DHFR,LINC01257,PARPBP,RAN,MEMO1,CRYL1,DCUN1D2,SPATA9,EFS,ARSK,ADGRV1,USP44,FCAR,RELL1,POLK,PEAR1,FBXO11,NBEA,PLEKHA6,GFM2,STPG4,CGREF1,KIF21B,UHRF1BP1L,DRC1,ZBTB37,TBC1D1,TMED2,ARHGEF28,TEP1,TFDP1,ACTR6,ADAMTS19,TRPC4,GPN1,TECRL,NSD2,YTHDC2,ZNF324B,LMLN,KIR3DL1,AXDND1" MicroRNA hsa-miR-449c:mirSVR_highEffct hsa-miR-449c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.91E-18 4.74E-14 4.96E-17 4.54E-16 51 1049 "MDM4,SLAMF6,SNX24,STXBP6,ASCL1,SLC5A8,PDGFRA,CENPC,CFAP54,TM9SF2,SMIM14,ATAD2B,JAKMIP1,HECTD1,LYSMD3,PREPL,ZFYVE16,BIVM,COG3,RABGAP1L,NR1H4,SMC6,RGS4,MBNL2,MARVELD2,GP6,EFS,HSD17B7,G2E3,SLC12A2,MYO16,GABRA2,MYT1L,IQGAP2,NPAS3,CMPK2,RBKS,ERBIN,PSME4,MTUS2,TGFBI,GTF3C2,RIMBP2,ATP6V0A2,WDR36,NSD2,FCRL6,MZF1,SPTSSA,ANKS1B,LCP1" MicroRNA hsa-miR-1205:mirSVR_highEffct hsa-miR-1205:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.10E-18 4.84E-14 5.06E-17 4.63E-16 43 748 "MAP1B,ACOX3,KIAA1211,CUL4A,SLC4A4,ARHGEF7,CCNA1,CAST,SNTG2,ZNF664,PDGFRA,RNASE9,LACC1,IL20,SPATA18,G3BP2,NR1I3,GALNT14,EGLN3,AASDH,PACRGL,GMPR2,TOMM40L,RELL1,PIBF1,STAB2,SLC22A4,MYT1L,GABRB1,CIDEB,IKBIP,PSME4,ADAM17,RIPK3,HEXB,ADAMTS19,HSD17B4,TENT2,ZMYM2,SDR39U1,LHX9,MFSD2B,RMST" MicroRNA hsa-miR-139-5p:mirSVR_highEffct hsa-miR-139-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.22E-18 4.90E-14 5.12E-17 4.69E-16 47 895 "RALGAPA1,NDRG2,EP400,MSH2,PPP1R12B,UHMK1,ZNF664,CDK7,PDE4D,PDE6B,RCBTB2,SLC25A3,LYSMD3,C12orf65,LOC439933,CEP350,TINF2,MBNL2,UGT2A3,TBC1D19,CWC27,MAEA,POLK,FLT1,RASA3,TMEM132D,NR5A2,CHFR,KDM5B,ERAP1,HSPH1,ERBIN,PSME4,KMT5A,BAZ1A,ADAMTS19,HMGCR,GUF1,TENT2,CCDC169,ANKS1B,FAM151B,RNASE11,LCP1,LINC00442,RMST,CDK2AP1" MicroRNA hsa-miR-16-5p:Functional MTI Functional MTI miRTarbase 9.36E-18 4.98E-14 5.20E-17 4.76E-16 63 1557 "ABL2,TBC1D14,ULK1,CUL4A,MCFD2,DHX37,MSH2,NOP14,BTF3,PNP,PCK2,CDK17,PDE4D,CFL2,GPR180,TM9SF2,NRXN1,SNX6,CFAP45,NOC4L,CRHBP,NCOR2,SREK1,PTGS2,G3BP2,RAN,TMEM161B,IPO4,CLIP4,LRPPRC,RNASEL,SBNO1,UTP15,VEZT,ALKAL2,IVNS1ABP,SLC12A2,MRPS14,CENPJ,ATP8A2,HSPH1,SRP72,ANKLE2,PSME4,UTP20,PPIP5K2,METAP2,EML4,DOCK9,COP1,XPO4,NCSTN,TEP1,TGFBI,GTF3C2,HSP90B1,TADA2B,SELENOI,TDRD3,CHPT1,KIF2A,LIG4,MICU2" MicroRNA hsa-miR-625:mirSVR_highEffct hsa-miR-625:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.81E-18 5.22E-14 5.44E-17 4.98E-16 50 1012 "IL17D,NDRG2,WDR35,SEMA6A,FBRSL1,CENPBD1P1,ZNF542P,MPZL1,DCLK1,CFL2,TM9SF2,ATAD2B,GNPTAB,TOGARAM2,PM20D1,SNCAIP,ITSN2,FAM169A,ZNF586,BIVM,SREK1,COCH,OCIAD1,G3BP2,ATG10,POLR1D,ARSK,VEZT,TM9SF1,WDCP,YPEL5,ACIN1,JPH4,NAAA,EAPP,GJB2,ADGRL3,RNF212,TGFBI,RAB2B,UBE2K,TXK,IL25,KCNT2,MZF1,JCHAIN,IRF1,KIT,LCP1,PABPN1" MicroRNA hsa-miR-367*:mirSVR_highEffct hsa-miR-367*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-17 5.98E-14 6.23E-17 5.70E-16 46 862 "SLAMF6,BLZF1,KCTD12,CAST,ZMYM5,FAM177A1,THAP6,POU2F1,CSNK1G3,CEP135,NOS1AP,MATR3,SPATA18,DGKQ,PTPRC,OCIAD1,NR1H4,GUSBP3,PACRGL,EIF2B1,ELF1,TOMM40L,GORAB,N4BP2L2,VEZT,ALKAL2,PKD2L2,LIMCH1,CYP1B1-AS1,SRP72,ERBIN,LILRB1,COMMD6,TMED2,ADGRL3,TCF7,YIPF7,CRB1,TECRL,GUF1,TENT2,YTHDC2,ZNF470,IL6ST,LINC01913,ZNF304" MicroRNA hsa-miR-432*:mirSVR_lowEffct hsa-miR-432*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-17 6.92E-14 7.20E-17 6.59E-16 61 1479 "MCC,TMEM132B,APC,MSH2,ZNF784,ATP2B4,NFATC4,AMDHD1,PDE4D,PDE6B,CCDC122,GNPTAB,CLOCK,PREPL,NCOR2,CEP135,NOS1AP,MATR3,DMXL1,OCIAD1,F11R,G3BP2,PARPBP,TSEN15,NR1I3,B3GLCT,RB1,POLR1D,PACRGL,SNORA53,KLHL12,ARSK,CWC27,STK32B,MAEA,PCBD2,FCAR,RELL1,PIBF1,POLK,SDC1,FLT1,TM9SF1,RUBCNL,SLC34A2,ARHGEF40,SLC22A4,MEGF10,NFASC,METAP2,C1QTNF9B,NT5C1B,CRB1,SLC7A8,AP4S1,ADAMTS19,C12orf73,CCDC169,PLB1,IRF1,KIF3C" MicroRNA hsa-miR-711:mirSVR_lowEffct hsa-miR-711:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-17 7.07E-14 7.35E-17 6.73E-16 54 1181 "KIAA1211,NYNRIN,RAB29,CACNA1E,NRL,RFLNA,ZNF664,PCCA,GLT1D1,ITGBL1,CPNE6,PIGR,HOMER1,TOGARAM2,SPATA18,EPS8L1,COG3,LOC439933,RABGAP1L,RGS12,ETF1,DNAJC27,ABCA11P,N4BP2L2,FGF9,RUBCNL,ZNF605,PKD2L2,C1orf112,DCAF11,MEGF10,KIF21B,PDS5B,NAAA,NPAS3,NFASC,ERBIN,PCDH17,PPIP5K2,ARHGEF28,TMPO,TPO,ADAMTS19,STARD4,NSD2,DCP2,YTHDC2,FCRL6,ZNF84,PLB1,LINC00272,CAB39L,SPRYD7,ZNF304" MicroRNA hsa-miR-378:mirSVR_highEffct hsa-miR-378:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.33E-17 7.08E-14 7.35E-17 6.73E-16 44 792 "HOMEZ,DDX55,BCL2L2,ARHGEF7,DAOA,NRL,CHAMP1,SLC5A8,PCCA,CHIT1,ZNF595,GPR180,TM9SF2,PIK3C2B,ATAD2B,DCAF8,TINF2,IPO4,RGS4,CLIP4,POLR1D,FCGR3A,FOXG1,MROH9,FLT1,VEZT,MBIP,IVNS1ABP,PKD2L2,GABRB1,ERAP1,MRPS27,STRN,GZMB,FZD10,UBE2K,GPN1,ZNF876P,VRK2,IL6ST,KIF2A,SLAMF9,NUAK2,SPRYD7" MicroRNA hsa-miR-497*:mirSVR_highEffct hsa-miR-497*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-17 7.22E-14 7.49E-17 6.86E-16 59 1393 "MDM4,BIRC6,ACOX3,NLN,TBC1D14,MCFD2,STXBP6,ASCL1,NLRP4,STARD13,PAH,FCRLB,CDK7,CDK17,RGSL1,CENPC,PFKFB2,VIT,NUP37,MPC2,NGDN,CEP135,BIVM,SREK1,NUDT12,OCIAD1,RNF219,ARGLU1,ZNF329,RGS12,SPATA9,ELF1,ARSK,PCBD2,UTP15,GORAB,POLK,FOXO1,SUPT20H,ZCCHC8,RUBCNL,G2E3,BRMS1L,THADA,RAPGEF6,NPAS3,CMPK2,NEDD1,PPARGC1A,LINC02393,GPR12,KMT5A,DOCK9,RNF212,GUF1,ZMYM2,LHX9,LAD1,SPRYD7" MicroRNA hsa-miR-1251:mirSVR_lowEffct hsa-miR-1251:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-17 7.23E-14 7.49E-17 6.86E-16 52 1100 "MDM4,NYNRIN,WDR35,HOMEZ,CUL4A,APBB2,BLZF1,ATP1A2,CAST,NFXL1,CDK17,JAKMIP1,AKAP6,TAPT1,SNCAIP,TTC37,EIF2AK2,NOS1AP,COG3,CEP120,PPP2R3C,TSEN15,DNMT3A,B3GLCT,ZNF219,ARSK,PCGF3,SH3YL1,FCAR,LRRN2,SUPT20H,VEZT,PAICS,UFM1,ARHGEF40,PKD2L2,SLC22A5,GABRA2,NFASC,LRCH1,NPFFR2,LPIN1,STRN,NCSTN,CRB1,ACTR6,IGF1,SPTSSA,ZMYM2,KCNN2,CAB39L,PABPN1" MicroRNA hsa-miR-636:mirSVR_highEffct hsa-miR-636:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-17 7.36E-14 7.62E-17 6.98E-16 39 618 "SEMA6A,CENPBD1P1,ATP2B4,CCNA1,ADGRD1,CBLN3,FCHO2,CD1E,PCDH9,CDK17,RGSL1,ITGBL1,LYSMD3,CRHBP,BRI3BP,FCRL5,OCIAD1,RABGAP1L,GNPDA2,POLR1D,PACRGL,MBNL2,FAM172A,ETF1,IRF9,FCGR3A,PIBF1,PLEKHA6,PKD2L2,CGREF1,GABRB1,ZBTB37,STRN,DOCK9,PAPPA2,LHX9,NPHS2,CHPT1,LINC01913" MicroRNA hsa-miR-384:mirSVR_highEffct hsa-miR-384:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.40E-17 7.45E-14 7.71E-17 7.06E-16 48 943 "RALGAPA1,MDM4,ACOX3,ADGRD1,CD1E,GLT1D1,PGGT1B,STRN3,PREPL,CEP135,SREK1,DMXL1,NUDT12,SACS,TSEN15,ATG10,LAP3,RGS12,PACRGL,MBNL2,FCAMR,CLIP1,IRF9,TOMM40L,NUBPL,SLC8A1,TADA1,CCDC88A,LIMCH1,CYP1B1-AS1,GABRB1,KDM5B,TMEM183A,SRP72,ERBIN,NMU,NPFFR2,PPARGC1A,INSM2,METAP2,C5orf56,NPL,SLAIN1,ZNF26,TDRD3,ZBED3-AS1,TTC41P,TTC7A" MicroRNA hsa-miR-3138:mirSVR_highEffct hsa-miR-3138:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-17 7.53E-14 7.78E-17 7.13E-16 47 905 "SEMA6A,ATP7B,CAST,RGSL1,PDGFRA,PMCH,AKAP6,TAPT1,LRRTM2,UBXN2A,GLT8D2,ZFYVE16,CEP120,C14orf119,NR1I3,FAM129A,DTD2,RGS12,POLR1D,GP6,GMPR2,TOMM40L,PIBF1,SELP,RUBCNL,SLC12A2,CGREF1,MEGF10,GABRB1,PDS5B,CENPJ,MRPS27,IKBIP,INSM2,STON1,CRB1,RIMBP2,TENT2,ZFHX2,SDR39U1,NPHS2,TMEM178A,CAB39L,KIR2DL4,KIR3DL2,KIT,AXDND1" MicroRNA hsa-miR-193a-3p:mirSVR_lowEffct hsa-miR-193a-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-17 7.76E-14 8.01E-17 7.33E-16 56 1267 "IL17D,ADD1,APC,NOP14,CENPBD1P1,BCL2L2,CAST,PCDH9,XPR1,PDE4D,PDGFRA,NLRC4,PIGR,AKAP6,TOGARAM2,FCRL5,NOS1AP,MTX3,SLC35F6,GALNT14,RNASEL,TXNDC15,KIRREL1,GP6,FAM172A,ETF1,ADGRV1,PCGF3,CLIP1,STAB2,LIMCH1,ZNF274,CD244,UHRF1BP1L,ERAP1,NPAS3,NFASC,ZBTB37,PSME4,ZNF544,ATP11A,CNTN2,YIPF7,CRB1,AP4S1,MAEL,ATP6V0A2,NPL,ZNF876P,IRF1,TDRD3,KCNJ9,KIT,RILPL2,TTC41P,SKA3" MicroRNA hsa-miR-346:mirSVR_lowEffct hsa-miR-346:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-17 7.90E-14 8.15E-17 7.46E-16 53 1143 "PPFIA4,MSH2,DDX55,ARL1,RGSL1,PDE4D,PDGFRA,SMIM14,JAKMIP1,THAP6,FAM163A,CRHBP,BRI3BP,VCAN,C12orf65,ITSN2,EPS8L1,PIGG,EGLN3,MBNL2,LGR6,ZNF671,EFS,DLEU1,ABCA11P,F7,GORAB,SUCO,ALKAL2,UFM1,ZNF605,CGREF1,LIMCH1,GABRB1,PDS5B,CMPK2,NFASC,ZNF544,ATP11A,MTUS2,GOLGA3,ADGRL3,ADGRA3,EML4,CRB1,NPL,TENT2,ZMYM2,KCNJ9,AXDND1,LIG4,IFT88,ZNF304" MicroRNA hsa-miR-1226*:mirSVR_highEffct hsa-miR-1226*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-17 8.06E-14 8.30E-17 7.60E-16 42 723 "CARMIL3,NFKBIA,RAB29,RGSL1,WDFY2,CFAP54,SMIM14,CFAP45,SNCAIP,OCIAD1,LINC01257,RNF219,SMC6,RNASE2,LGR6,ETF1,ABCA11P,TRAPPC13,TNFRSF19,RELL1,RUBCNL,MBIP,IVNS1ABP,CGREF1,MYO16,KIF21B,ZNF274,NPAS3,MAST4,LINC02393,ADGRA3,KMT5A,RNF212,NCSTN,FCRLA,FZD10,ZNF721,ARHGAP30,MZF1,ZNF140,KIR2DS4,TTC41P" MicroRNA hsa-miR-24-1*:mirSVR_lowEffct hsa-miR-24-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-17 8.13E-14 8.37E-17 7.66E-16 44 795 "MDM4,APAF1,APC,BLZF1,ARHGAP5,ARL1,ASTN1,CACNA1E,MPZL1,CAST,THAP6,LYSMD3,SNCAIP,LACC1,DNM3,MATR3,SREK1,TINF2,MEMO1,MARVELD2,MAEA,ABCA11P,TRAPPC13,SULT6B1,PEAR1,PAICS,CCDC88A,ZNF605,C1orf112,DCAF11,ATP8A2,NFASC,LILRB1,TBC1D1,LILRB4,TEP1,TMPO,ADAMTS19,ARHGAP30,TECRL,IL6ST,IRF1,KIR2DL4,KIR2DS4" MicroRNA hsa-miR-3142:mirSVR_lowEffct hsa-miR-3142:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.56E-17 8.27E-14 8.50E-17 7.78E-16 58 1354 "MDM4,HOMEZ,DDX55,BLZF1,ZNF542P,NLRP4,NRL,CDKL2,FCHO2,UHMK1,FCRLB,CHD1,CHIT1,PIGR,TAPT1,SNCAIP,FAM169A,KIAA0040,CMTM5,DCAF8,COG3,LINC01257,RASA1,OGFOD2,RGS4,CLIP4,EIF2D,FCAMR,FAM81B,DNAJC27,PCGF3,ARL6IP4,SULT6B1,PEAR1,FLT1,FLT3,HSD17B7,GOLGA2P5,BRMS1L,NUBPL,SLC8A1,SLC15A4,WDCP,EFR3B,MEGF10,JPH4,DHRS4,PSME4,RIPK3,ZBTB49,NPL,TECRL,ZNF550,STARD4,ZNF470,C12orf73,PLB1,TTC41P" MicroRNA hsa-miR-3201:mirSVR_highEffct hsa-miR-3201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-17 8.31E-14 8.53E-17 7.81E-16 38 587 "SNX24,LINC02347,CDKL2,CD1E,PCDH9,PGGT1B,ADGRF3,THAP6,DCAF8,RABGAP1L,DHFR,TMEM161B,REST,RGS12,MEMO1,LRPPRC,SNORA49,CWC27,GORAB,STAB2,UFM1,IVNS1ABP,N4BP2,NR5A2,LIMCH1,EAPP,IQGAP2,MIMT1,ZBTB37,MAST4,METAP2,ADAMTS19,CENPH,CCDC169,ZNF140,FAM151B,DIAPH3,RMST" MicroRNA hsa-miR-500*:mirSVR_lowEffct hsa-miR-500*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-17 8.60E-14 8.82E-17 8.08E-16 56 1270 "TBC1D14,ADCY4,MSH2,NCOA1,SLC4A4,ATP2B4,LINC02347,CDK18,ATAD2B,THAP6,STRN3,NGDN,VCAN,C12orf65,KIAA0040,DCAF8,SPATA18,COG3,PTGS2,DMXL1,PTPRH,LINC01257,OGFOD2,TXNDC15,EIF2B1,SNORA53,DRAM1,MAEA,FCAR,SUPT20H,RASA3,BRMS1L,LIMCH1,DCAF11,CD244,NPAS3,MRPS27,NFASC,COMMD6,LPIN1,PPARGC1A,TBC1D1,ATP11A,ARHGEF28,RNF212,ACTR6,TNR,TMEM174,RXFP2,ZNF876P,STARD4,CENPH,LAD1,RMST,LMNB1,IFT88" MicroRNA hsa-miR-196a:mirSVR_lowEffct hsa-miR-196a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.73E-17 9.22E-14 9.44E-17 8.65E-16 56 1272 "NYNRIN,EP400,ASCL1,CENPBD1P1,NFKBIA,NOVA1,PNP,CAST,FCHO2,MORN2,RGSL1,PDGFRA,ITGBL1,PIK3C2B,FAM169A,DNM3,UBXN2A,ZNF586,ZFYVE16,PIGG,PARPBP,B3GLCT,RASA1,ZNF329,AASDH,MEMO1,GUSBP3,ZNF671,CLIP1,SUCO,HSD17B7,ZNF605,NR5A2,EFR3B,CMPK2,MIMT1,CFHR4,GJB2,MAST4,TCF7,DOCK9,RNF212,CRB1,RASSF6,GZMH,MAEL,NPL,WDR36,NSD2,KCNT2,ZNF84,PLB1,KCNN2,LINC00442,RMST,PABPN1" MicroRNA hsa-miR-483-3p:mirSVR_highEffct hsa-miR-483-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-17 9.65E-14 9.88E-17 9.05E-16 39 623 "BIRC6,CENPBD1P1,CCNA1,PAH,PIWIL1,HOMER1,RCHY1,SNCAIP,CSNK1G3,FCRL2,DCAF8,TINF2,NR1H4,RB1,ARGLU1,AASDH,LAP3,EIF2D,PACRGL,KLHL12,MARVELD2,STX2,FAM172A,UTP15,SLC22A4,LIMCH1,JPH4,RAPGEF6,TMEM183A,UHRF1BP1L,MRPS27,MAST4,METAP2,C5orf56,RNF212,KCNN2,RNASE11,PABPN1,SPATA13" MicroRNA hsa-miR-2116*:mirSVR_highEffct hsa-miR-2116*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-17 9.67E-14 9.89E-17 9.06E-16 40 657 "MDM4,NDRG2,ATP4B,MYH6,PDGFRA,PIWIL1,CFAP54,NRXN1,HECTD1,HOMER1,PMCH,RCHY1,ITSN2,PIGG,SREK1,NR1H4,TXNDC15,ARSK,DLEU1,ELOVL7,NDUFAF7,SUCO,SFSWAP,SLC22A5,GABRA2,PDS5B,NAAA,NPAS3,DRC1,ZBTB37,TMED2,ADGRL3,LILRB4,AP4S1,MAEL,TENT2,SPTSSA,ZMYM2,TTC41P,PABPN1" MicroRNA hsa-miR-4257:mirSVR_highEffct hsa-miR-4257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.84E-17 9.78E-14 9.99E-17 9.15E-16 44 799 "SFTA3,MDM4,KIAA1211,CUL4A,ASCL1,B4GALT3,NOVA1,PCK2,ATAD2B,ADGRF3,HEATR5A,LYSMD3,ITSN2,CEP135,PIGG,SREK1,CEP350,NUDT12,TINF2,PARPBP,RASA1,OGFOD2,POLR1D,LATS2,ABCA11P,UTP15,NUBPL,STPG4,THADA,EFR3B,PDS5B,LPIN1,PPARGC1A,TFDP1,ZNF721,GPN1,C12orf73,IL6ST,PLB1,LHX9,TMEM178A,RMST,SPRYD7,ZNF304" MicroRNA hsa-miR-3200:mirSVR_lowEffct hsa-miR-3200:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-17 9.89E-14 1.01E-16 9.24E-16 51 1068 "MATN3,MDM4,BIRC6,KIAA1211,MIPEP,MSH2,NCOA1,SLC4A4,CACNA1E,CBLN3,CDKL2,CD1D,PCCA,RGSL1,PDGFRA,ZNF595,GPR180,NRXN1,THAP6,BRI3BP,DCAF8,MATR3,SPATA18,DMXL1,OCIAD1,SETDB2,MBNL2,DHRS2,GP6,FAM172A,ZNF219,CWC27,PCGF3,PCBD2,THADA,MYT1L,HSPH1,TMED2,C5orf56,TCF7,EML4,TXK,TMEM174,SLAIN1,NSD2,ANKS1B,NPHS2,KCNJ9,LMLN,LMNB1,SPATA13" MicroRNA hsa-miR-429:TargetScan hsa-miR-429 TargetScan 1.90E-17 1.01E-13 1.03E-16 9.41E-16 46 874 "MAP1B,MCC,CUL4A,MCFD2,APAF1,PPP1R12B,NOVA1,CDK17,CFL2,CHD1,ATAD2B,PKP1,LYSMD3,CLOCK,NCOR2,CSNK1G3,KIAA0040,MATR3,DHX9,CEP350,KLHL3,DNMT3A,ARGLU1,EFNA5,LATS2,ELK3,ETF1,CLIP1,POLK,FOXG1,FLT1,BRMS1L,PLEKHA6,N4BP2,NR5A2,PDS5B,KDM3B,NFASC,NEDD1,LPIN1,PSME4,ATP6V0A2,KLF12,IL6ST,LHX9,LOX" MicroRNA hsa-miR-200b-3p:TargetScan hsa-miR-200b-3p TargetScan 1.90E-17 1.01E-13 1.03E-16 9.41E-16 46 874 "MAP1B,MCC,CUL4A,MCFD2,APAF1,PPP1R12B,NOVA1,CDK17,CFL2,CHD1,ATAD2B,PKP1,LYSMD3,CLOCK,NCOR2,CSNK1G3,KIAA0040,MATR3,DHX9,CEP350,KLHL3,DNMT3A,ARGLU1,EFNA5,LATS2,ELK3,ETF1,CLIP1,POLK,FOXG1,FLT1,BRMS1L,PLEKHA6,N4BP2,NR5A2,PDS5B,KDM3B,NFASC,NEDD1,LPIN1,PSME4,ATP6V0A2,KLF12,IL6ST,LHX9,LOX" MicroRNA hsa-miR-200c-3p:TargetScan hsa-miR-200c-3p TargetScan 1.90E-17 1.01E-13 1.03E-16 9.41E-16 46 874 "MAP1B,MCC,CUL4A,MCFD2,APAF1,PPP1R12B,NOVA1,CDK17,CFL2,CHD1,ATAD2B,PKP1,LYSMD3,CLOCK,NCOR2,CSNK1G3,KIAA0040,MATR3,DHX9,CEP350,KLHL3,DNMT3A,ARGLU1,EFNA5,LATS2,ELK3,ETF1,CLIP1,POLK,FOXG1,FLT1,BRMS1L,PLEKHA6,N4BP2,NR5A2,PDS5B,KDM3B,NFASC,NEDD1,LPIN1,PSME4,ATP6V0A2,KLF12,IL6ST,LHX9,LOX" MicroRNA hsa-miR-635:mirSVR_highEffct hsa-miR-635:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.92E-17 1.02E-13 1.04E-16 9.48E-16 40 658 "MDM4,DDX55,BTF3,FCHO2,LDB2,UHMK1,PAH,ZNF664,PCDH9,CDK18,PDE6B,GPR180,THAP6,THTPA,FCRL5,BIVM,SPATA18,DNMT3A,AASDH,RNASEL,EIF2B1,FCAMR,GMPR2,NDUFAF7,FOXG1,PAICS,ARHGEF40,GABRA2,GABRB1,SRP72,MCCC2,ANO4,RAB2B,HSD17B4,PAPPA2,ZFHX2,ZNF84,ZBED3-AS1,KIF3C,DIAPH3" MicroRNA hsa-miR-141:PITA hsa-miR-141:PITA_TOP PITA 2.13E-17 1.13E-13 1.15E-16 1.05E-15 39 626 "ABL2,SEMA6A,APBB2,ASTN1,KCTD12,MPZL1,PCDH9,XPR1,CDK17,CFL2,SLC25A3,NRXN1,ATAD2B,EPN1,HECTD1,CLOCK,CSNK1G3,PRKD1,SREK1,DMXL1,CEP120,LATS2,STX2,PCGF3,TMEM129,SUPT20H,TADA1,MEGF10,MYT1L,PDS5B,ATP8A2,KDM3B,NFASC,PPARGC1A,KHNYN,KLF12,VRK2,NSD2,DCP2" MicroRNA hsa-miR-200a:PITA hsa-miR-200a:PITA_TOP PITA 2.13E-17 1.13E-13 1.15E-16 1.05E-15 39 626 "ABL2,SEMA6A,APBB2,ASTN1,KCTD12,MPZL1,PCDH9,XPR1,CDK17,CFL2,SLC25A3,NRXN1,ATAD2B,EPN1,HECTD1,CLOCK,CSNK1G3,PRKD1,SREK1,DMXL1,CEP120,LATS2,STX2,PCGF3,TMEM129,SUPT20H,TADA1,MEGF10,MYT1L,PDS5B,ATP8A2,KDM3B,NFASC,PPARGC1A,KHNYN,KLF12,VRK2,NSD2,DCP2" MicroRNA hsa-miR-761:mirSVR_highEffct hsa-miR-761:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-17 1.25E-13 1.27E-16 1.16E-15 47 917 "LRRC43,SNX24,ASTN1,NFATC4,NOVA1,NRL,PAH,RGSL1,PDGFRA,PGGT1B,WDFY2,AKAP6,LYSMD3,CMTM5,PPP2R3C,TMEM161B,TMEM33,CLIP4,SETDB2,CWC27,STK32B,PIBF1,VEZT,GOLGA2P5,SLC8A1,CHFR,MYT1L,PDS5B,NAAA,ZNF274,NPAS3,MCCC2,DHRS4,ZNF544,UGT2A1,C5orf56,DOCK9,COP1,HEXB,ADAMTS19,RXFP2,TENT2,IL25,DCP2,IGF1,ANKS1B,FAM49A" MicroRNA hsa-miR-509-5p:mirSVR_highEffct hsa-miR-509-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-17 1.27E-13 1.29E-16 1.18E-15 48 956 "RALGAPA1,MDM4,CDKL4,ARHGEF7,CCNA1,ADGRD1,DAOA,CBLN3,CAST,FCHO2,UHMK1,NFXL1,CDK17,PDGFRA,ATAD2B,AKAP6,ITSN2,SACS,G3BP2,RAN,POLR1D,F7,TOMM40L,RELL1,PEAR1,SELP,FBXO11,G2E3,NBEA,ZNF446,TADA1,N4BP2,YPEL5,ERAP1,LILRB1,UTP20,ADGRA3,TDG,HEXB,TENT2,ZFHX2,IL6ST,ZMYM2,SDR39U1,LHX9,ZBED3-AS1,FAM71C,PABPN1" MicroRNA hsa-miR-4256:mirSVR_lowEffct hsa-miR-4256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-17 1.30E-13 1.31E-16 1.20E-15 56 1282 "SMIM15,MDM4,ACOX3,WDR35,FAM193A,CCNA1,NOVA1,PAH,PDE4D,WDFY2,POLN,HOMER1,C1orf116,PRKD1,PIGG,PARPBP,DNMT3A,RAN,RNF31,LAP3,SETDB2,TXNDC15,RNF4,ELF1,MPHOSPH9,MARVELD2,BORA,UTP15,SLC34A2,UFM1,ZNF605,N4BP2,WDCP,FSHR,NR5A2,MEGF10,ZNF274,MRPS27,SRP54,LILRB1,LPIN1,MTUS2,LILRB4,TCF7,STON1,GTF3C2,NPL,TENT2,STARD4,NSD2,DCP2,MZF1,C12orf73,KCNN2,FIP1L1,KIR2DL4" MicroRNA hsa-miR-186*:mirSVR_highEffct hsa-miR-186*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-17 1.31E-13 1.32E-16 1.21E-15 46 880 "SMIM15,NCOA1,CAST,PCK2,WDR66,PIWIL1,PGGT1B,SMIM14,ATAD2B,EPN1,AKAP6,EPGN,SREK1,PTGS2,DNMT3A,ZNF329,AASDH,RNASE2,NDUFAF7,FOXO1,HSD17B7,BRMS1L,THADA,LIMCH1,GABRA2,KDM5B,NAAA,CD244,ERAP1,MRPS27,GC,PSME4,ADGRL3,DOCK9,COP1,HAL,ADAMTS19,KLF12,STARD4,IL25,NSD2,NPHS2,CHPT1,TTC41P,DNAH10,RMST" MicroRNA hsa-miR-647:mirSVR_highEffct hsa-miR-647:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-17 1.32E-13 1.33E-16 1.22E-15 40 663 "MSH2,NCOA1,PPP1R12B,NFATC4,NOVA1,DAOA,ODC1,FCHO2,UHMK1,RGSL1,PDE6B,CHD1,ZNF595,CFAP54,POU2F1,LACC1,TSEN15,IPO4,ABCA11P,GORAB,SUPT20H,ATP8A2,CMPK2,NFASC,ZBTB37,METAP2,ANO4,C1QTNF9B,ZBTB49,LINC01551,TNR,ADAMTS19,GPN1,TECRL,GUF1,TMEM174,ZBTB41,MFSD2B,LCP1,LMNB1" MicroRNA hsa-miR-744*:mirSVR_highEffct hsa-miR-744*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.58E-17 1.37E-13 1.38E-16 1.27E-15 38 596 "SLAMF6,MSH2,STXBP6,CAST,ITGBL1,SNX6,LTB4R,TAPT1,POU2F1,HEATR5A,CSNK1G3,IFT172,MATR3,DMXL1,NR1H4,EGLN3,MEMO1,LATS2,ELF1,TBC1D19,UTP15,FGF9,FOXG1,STAB2,PKD2L2,MEGF10,KLHL20,COMMD6,ZBTB37,PPARGC1A,LINC02393,METAP2,STON1,CRB1,ADAMTS19,IL6ST,FIP1L1,LINC01913" MicroRNA hsa-miR-205:mirSVR_highEffct hsa-miR-205:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.60E-17 1.38E-13 1.39E-16 1.27E-15 48 958 "MDM4,MSH2,DDX55,B4GALT3,KCTD12,NFXL1,PCCA,FAM177A1,RGSL1,CFL2,TAPT1,LYSMD3,LACC1,ZFYVE16,SPATA18,COG3,DMXL1,OCIAD1,DHFR,RGS12,PACRGL,BORA,TBC1D19,DRAM1,CWC27,ETF1,ABCA11P,CLIP1,ELOVL7,NDUFAF7,IVNS1ABP,THADA,SLC15A4,N4BP2,DCAF11,SNRPF,JPH4,UHRF1BP1L,GJB2,EML4,UBE2K,ZNF550,PAPPA2,KCNT2,FAM151B,CAB39L,RMST,SPATA13" MicroRNA hsa-miR-302f:mirSVR_highEffct hsa-miR-302f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-17 1.45E-13 1.46E-16 1.34E-15 50 1038 "UVSSA,MYH7,CCNA1,DAOA,FCHO2,PCK2,PDE4D,PDGFRA,ITGBL1,THAP6,TOGARAM2,LYSMD3,CRHBP,ITSN2,PTPRC,GNPDA2,DHFR,NR1H4,CLIP4,PACRGL,MARVELD2,ARSK,PCBD2,VEZT,RUBCNL,TADA1,YPEL5,EFR3B,GABRB1,FAM114A1,HSPH1,NPAS3,CMPK2,SULT1E1,ADGRL3,GPR12,ARHGEF28,TDG,CRB1,HAL,POC5,HTR2A,KCNT2,JCHAIN,PLB1,NPHS2,CHPT1,CAB39L,LCP1,RMST" MicroRNA hsa-miR-610:mirSVR_lowEffct hsa-miR-610:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.93E-17 1.56E-13 1.56E-16 1.43E-15 55 1245 "MAP1B,WDR35,SNX24,MCFD2,FAM193A,CENPBD1P1,CCNB1IP1,STARD13,BCL2L2,ODC1,CHAMP1,PFKFB2,SLC25A3,HECTD1,FAM163A,SNCAIP,CEP135,DNM3,UBXN2A,MPHOSPH8,FCRL5,COCH,CEP120,GNPDA2,SLC35F6,RAN,FAM129A,TMEM33,SETDB2,PACRGL,PCGF3,F7,ELOVL7,PEAR1,FTLP10,SH3BP2,PLEKHA6,PAICS,SLC8A1,CYP1B1-AS1,SNRPF,RIPK3,COX18,FCRLA,GPN1,NSD2,YTHDC2,ZNF470,SPTSSA,ZBED3-AS1,KCNN2,CAB39L,KIT,TTC41P,LIG4" MicroRNA hsa-miR-1244:mirSVR_lowEffct hsa-miR-1244:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.02E-17 1.61E-13 1.61E-16 1.48E-15 65 1687 "MDM4,TBC1D14,WDR35,HOMEZ,MCFD2,CCDC181,SLC4A4,RAB29,DAOA,CAMK4,FCHO2,ZNF664,DCLK1,RGSL1,ADGRF3,HOMER1,TAPT1,HEATR5A,LYSMD3,CEP135,KIAA0040,FCRL5,DCAF8,PIGG,KLHL3,PTPRC,DHFR,DTD2,TMEM33,RNASEL,LATS2,FAM172A,ARSK,PCGF3,TOMM40L,RASA3,ARHGEF40,ZNF605,P2RX2,LIMCH1,KDM5B,HSPH1,IKBIP,CFHR4,GJB2,TMED2,RIPK3,EML4,DOCK9,TDG,RNF17,GRSF1,ZBTB49,AP4S1,GTF2H3,RAB2B,ZNF876P,NLRP8,PAPPA2,ANKS1B,LMLN,KIF2A,DNAH10,TTC7A,SKA3" MicroRNA hsa-miR-575:mirSVR_lowEffct hsa-miR-575:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.20E-17 1.70E-13 1.71E-16 1.56E-15 58 1376 "RALGAPA1,EP400,MCFD2,WDR19,SLC4A4,NFATC4,NOVA1,CCNB1,CPNE6,HECTD1,THAP6,LRRTM2,EIF2AK2,DCAF8,SNX17,COG3,DHX9,FAM129A,RB1,RGS4,LATS2,TBC1D19,EFS,IRF9,NDUFAF7,FNIP1,TNFRSF19,HSD17B7,RASA3,NBEA,THADA,POTEM,P2RX2,WDCP,SLC22A4,NR5A2,MEGF10,PDS5B,KDM5B,EAPP,ZNF274,ATP8A2,CMPK2,KLHL20,MIMT1,LPIN1,PSME4,ARHGEF28,STON1,DOCK9,MAEL,ADAMTS19,HSP90B1,ZNF26,ANKS1B,CHPT1,KIF3C,SLAMF9" MicroRNA hsa-miR-195:mirSVR_highEffct hsa-miR-195:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.24E-17 1.72E-13 1.73E-16 1.58E-15 59 1420 "RGS5,ATP4B,MYBPC1,BCL2L2,NOVA1,PCDH9,CDK17,GLT1D1,CFL2,GPR180,ITGBL1,CFAP54,CFAP45,JAKMIP1,THAP6,PREPL,IL20,LRRTM2,FCRL2,DCAF8,PIGG,COCH,CEP120,TMEM161B,CLIP4,LATS2,MBNL2,TBC1D19,ABCA11P,ELOVL7,FGF9,SUCO,FLT3,RUBCNL,BRMS1L,IVNS1ABP,ARHGEF40,SLC15A4,SLC22A4,MYT1L,NPAS3,NFASC,LRCH1,PCDH17,ZNF544,INSM2,COP1,NT5C1B,FZD10,GPN1,HTR2A,ZMYM2,CHPT1,KIF2A,KIR2DS4,LINC01913,LCP1,RMST,SPRYD7" MicroRNA hsa-miR-767-3p:mirSVR_highEffct hsa-miR-767-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.47E-17 1.84E-13 1.85E-16 1.69E-15 46 888 "ADD1,CUL4A,PPFIA4,LTB4R,POU2F1,NGDN,SPATA18,PIGG,FBXL5,NUDT12,PTPRC,RNASEL,LATS2,MARVELD2,ARSK,CWC27,DLEU1,ABCA11P,GMPR2,PIBF1,POLK,ZCCHC8,PLEKHA6,CCDC88A,P2RX2,SLC22A5,NPFFR2,LPIN1,GJB2,MAST4,ZNF544,ANO4,C5orf56,ZNF721,GUF1,ZNF550,HTR2A,SPTSSA,ZBED3-AS1,KIF2A,TTC41P,LCP1,RMST,AXDND1,LMNB1,IFT88" MicroRNA hsa-miR-135a*:mirSVR_lowEffct hsa-miR-135a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.48E-17 1.85E-13 1.85E-16 1.69E-15 54 1208 "MDM4,RGS5,MCFD2,DHX37,ATP1A2,ATP2B4,STARD13,MORN2,GLT1D1,WDFY2,PIK3C2B,PTPRVP,THAP6,EPGN,GLT8D2,DCAF8,IFT172,FBXL5,CEP350,OCIAD1,GNPDA2,EGLN3,RASA1,TMEM161B,EFNA5,TCTN2,GP6,STK32B,ETF1,PCBD2,TOMM40L,PIBF1,FTLP10,FBXO11,ZNF605,YPEL5,ACIN1,KIF21B,NMNAT2,KDM3B,NFASC,GJB2,UGT2A1,MSH6,RIMBP2,TPO,NLRP8,PAPPA2,KCNT2,ZBTB41,NPHS2,KCNN2,KIT,EP400P1" MicroRNA hsa-miR-621:mirSVR_lowEffct hsa-miR-621:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-17 1.91E-13 1.91E-16 1.75E-15 43 777 "WDR35,HOMEZ,PPFIA4,BLZF1,ARL1,PROZ,MPZL1,ODC1,UHMK1,ITGBL1,CFAP54,NRXN1,PKP1,JAKMIP1,LTB4R,TAPT1,ITSN2,EIF2AK2,PIGG,SREK1,PTGS2,COCH,LAP3,RNASEL,ELK3,DHRS2,EFS,POLK,SUPT20H,PAICS,SLC12A2,CYP1B1-AS1,GC,STRN,TBC1D1,EML4,COX18,CRB1,LINC01551,ADAMTS19,HSD17B4,ZNF470,LETM1" MicroRNA hsa-miR-142-5p:PITA hsa-miR-142-5p:PITA_TOP PITA 3.62E-17 1.93E-13 1.92E-16 1.76E-15 42 741 "RALGAPA1,ULK1,CUL4A,ASCL1,SLC4A4,STARD13,KCTD12,CDKL2,FCHO2,LDB2,UHMK1,CDK17,PDE4D,PDGFRA,BOD1L1,CSNK1G3,CEP120,SACS,EGLN3,PCGF3,FNIP1,SUPT20H,NBEA,CCDC92,MBIP,SLC30A6,PKD2L2,SLC15A4,ACIN1,MYT1L,PDS5B,ATP11A,ADGRL3,GRSF1,MSH6,HEXB,TRPC4,SLAIN1,IGF1,ZNF470,IL6ST,KIT" MicroRNA hsa-miR-4301:mirSVR_lowEffct hsa-miR-4301:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.74E-17 1.99E-13 1.98E-16 1.82E-15 48 967 "RALGAPA1,TMEM132B,ADD1,ACOX3,STXBP6,SLC4A4,ZNF542P,NRL,RILPL1,ZNF664,PDGFRA,PIGR,STRN3,ITSN2,KIAA0040,MATR3,F11R,GNPDA2,CLIP4,PACRGL,RNASEL,ELK3,KLHL12,CWC27,F7,FCGR3A,TOMM40L,FCGR3B,FBXO11,G2E3,PAICS,CMPK2,NFASC,LRCH1,LPIN1,MAST4,ADGRL3,STON1,RNF212,SLC7A8,MAEL,HSP90B1,GPN1,GUF1,TMEM174,RXFP2,ZNF84,CAB39L" MicroRNA hsa-miR-3164:mirSVR_highEffct hsa-miR-3164:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-17 2.12E-13 2.11E-16 1.94E-15 49 1008 "BIRC6,NYNRIN,SNX24,DDX55,STARD13,ARHGEF7,TAF1B,AMDHD1,PCDH9,PDGFRA,GPR180,NRXN1,THAP6,C1orf116,AKAP6,GALNT9,VCAN,DNM3,BIVM,NUDT12,COCH,CEP120,OCIAD1,GNPDA2,WDR1,PARPBP,DTD2,RGS4,CLIP4,MBNL2,STX2,PCBD2,FCGR2B,RELL1,FBXO11,NUBPL,ZNF605,P2RX2,CHFR,PSME4,TMED2,ADGRL3,RNF17,AP4S1,GUF1,TENT2,ZNF26,NPHS2,LOX" MicroRNA hsa-miR-3194:mirSVR_lowEffct hsa-miR-3194:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.03E-17 2.14E-13 2.13E-16 1.95E-15 60 1471 "NDRG2,NYNRIN,DHX37,PPFIA4,AACS,NFATC4,NOVA1,CACNA1E,ZNF664,CDK18,HECTD1,PTPRVP,GNPTAB,SNCAIP,GALNT9,NOS1AP,DCAF8,SNX17,BIVM,COG3,DMXL1,F11R,G3BP2,LINC01257,TSEN15,FAM129A,CLIP4,SETDB2,FCAMR,ZNF219,DRAM1,MAEA,ADGRV1,USP44,PCBD2,TMEM129,TNFRSF19,SDC1,FLT3,VEZT,ARHGEF40,EFR3B,KDM5B,GAK,CD244,ATP8A2,MIMT1,LPIN1,TBC1D1,PPIP5K2,GOLGA3,KMT5C,DOCK9,NT5C1B,SLC7A8,ADAMTS19,ZMYM2,IRF1,ANKDD1B,AXDND1" MicroRNA hsa-miR-888*:mirSVR_highEffct hsa-miR-888*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.62E-17 2.45E-13 2.44E-16 2.23E-15 52 1133 "DDX55,BLZF1,WDR19,ARHGAP5,ARL1,KCTD12,PROZ,CBLN3,CAD,PCCA,XPR1,PCSK1,SLC25A3,HOMER1,AKAP6,RCHY1,LACC1,KIAA0040,COG3,DMXL1,G3BP2,GNPDA2,SUPT7L,CLIP4,UGT2A3,MARVELD2,CWC27,STK32B,SUCO,SUPT20H,FBXO11,NUBPL,MBIP,SLC12A2,MRPS14,YPEL5,NPAS3,KDM3B,SRP72,PPARGC1A,BRD8,ADAM17,FCRLA,ZBTB49,LINC01551,TXK,TENT2,KCNT2,IL6ST,KIF2A,LOX,MICU2" MicroRNA hsa-miR-607:PITA hsa-miR-607:PITA_TOP PITA 4.76E-17 2.53E-13 2.51E-16 2.30E-15 47 934 "MAP1B,BIRC6,NCOA1,ATP2B4,KCTD12,ODC1,CCNB1,PDE4D,CFL2,NRXN1,ATAD2B,THAP6,LYSMD3,CEP135,DNM3,FBXL5,SUPT7L,EGLN3,POLR1D,MBNL2,PCGF3,CLIP1,PIBF1,SUCO,FBXO11,SLC8A1,SLC12A2,MYT1L,PDS5B,RAPGEF6,IQGAP2,KDM3B,ERBIN,PCDH17,GJA3,PPIP5K2,TDG,BAZ1A,RIMBP2,KLF12,GPN1,ZNF26,IGF1,KCNT2,ZBTB41,KIF2A,LMNB1" MicroRNA hsa-miR-1254:mirSVR_highEffct hsa-miR-1254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-17 2.53E-13 2.51E-16 2.30E-15 41 711 "NLN,CUL4A,MSH2,ARHGAP5,SLC4A4,KCTD12,NOVA1,NRL,PCCA,RGSL1,CHD1,PFKFB2,CHIT1,GPR180,PTPRVP,PM20D1,LACC1,FAM169A,DNM3,SNX17,PIGG,LOC439933,TINF2,SLC35F6,PARPBP,ATG10,CLIP1,STPG4,GABRA2,RBKS,ERBIN,IKBIP,ZBTB37,PPARGC1A,ADGRA3,ANO4,KMT5A,LINC01551,HEXB,STARD4,AXDND1" MicroRNA hsa-miR-3119:mirSVR_highEffct hsa-miR-3119:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.02E-17 2.67E-13 2.65E-16 2.42E-15 58 1390 "SMIM15,ADD1,APAF1,APC,FAM193A,DAOA,ZNF664,FAM177A1,SCFD2,CCDC122,PGGT1B,CFAP54,NRXN1,PIK3C2B,AKAP6,TOGARAM2,CRHBP,FCRL5,ZFYVE16,DMXL1,DHFR,GALNT14,B3GLCT,RNASEL,UGT2A3,MPHOSPH9,DNAJC27,PCGF3,GORAB,FNIP1,POLK,SUCO,NBEA,CCDC88A,C1orf112,CYP1B1-AS1,SNRPF,GABRA2,NAAA,ZNF274,MRPS27,PCDH17,PPARGC1A,GJB2,PPIP5K2,TCF7,FCRLA,AP4S1,RASSF6,TNNT2,ADAMTS19,HTR2A,MZF1,IL6ST,ZNF140,FAM151B,ZBED3-AS1,RMST" MicroRNA hsa-miR-657:mirSVR_highEffct hsa-miR-657:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.25E-17 2.79E-13 2.76E-16 2.53E-15 41 713 "SLAMF6,CUL4A,CAST,SLC5A8,GPR180,CFAP54,AKAP6,POU2F1,KIAA0040,FCRL5,FCRL2,GLT8D2,DCAF8,SREK1,TBC1D4,PPP2R3C,NR1I3,TMEM161B,SMC6,UGT2A3,EFS,ARSK,GORAB,NBEA,CCDC92,CCDC88A,ZNF605,YPEL5,MYT1L,PDS5B,SRP72,ANKLE2,LINC01551,ADAMTS19,LTB4R2,NLRP8,ZNF26,PGAM5,ZBED3-AS1,SPRYD7,TTC7A" MicroRNA hsa-miR-1260:mirSVR_lowEffct hsa-miR-1260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.31E-17 2.83E-13 2.80E-16 2.56E-15 67 1800 "IL17D,MDM4,TMEM132B,NLN,SNX24,DHX37,PPFIA4,APBB2,BLZF1,CCNB1IP1,B4GALT3,KCTD12,CBLN3,RILPL1,CCNB1,DCLK1,CENPC,CHIT1,MRPL57,PIK3C2B,ATAD2B,NCR1,STRN3,TAPT1,NCOR2,ITSN2,LRRTM2,CEP135,PRKD1,DCAF8,BIVM,RABGAP1L,SLC35F6,TSEN15,ATG10,RGS4,POLR1D,PACRGL,GP6,DRAM1,ETF1,TMEM156,FCGR3A,FLT1,HSD17B7,G2E3,DDX51,PLEKHA6,C1orf112,LIMCH1,PDS5B,NMNAT2,JPH4,RAPGEF6,OXGR1,MRPS27,ZNF544,LILRB4,FCRLA,MSH6,TNNT2,UBE2K,TMEM174,MZF1,CENPH,AXDND1,IFT88" MicroRNA hsa-let-7i:mirSVR_highEffct hsa-let-7i:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.43E-17 2.89E-13 2.85E-16 2.61E-15 43 786 "MDM4,SLAMF6,HOMEZ,BLZF1,WDR19,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,SPATA18,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RB1,RGS12,CWC27,PCGF3,CLIP1,NDUFAF7,GORAB,FNIP1,PIBF1,SUCO,VEZT,GABRA2,HSPH1,ZNF544,ACSL6,CRB1,PAPPA2,VRK2,ZNF10,SPRYD7,AXDND1" MicroRNA hsa-miR-635:mirSVR_lowEffct hsa-miR-635:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.55E-17 2.95E-13 2.91E-16 2.67E-15 61 1526 "MSH2,ARL1,CENPBD1P1,PPP1R12B,BCL2L2,ARHGEF7,RAB29,MPZL1,SYT2,FCGR2C,RCBTB2,WDFY2,FAM163A,TAPT1,SNCAIP,DNM3,ZFYVE16,EPS8L1,PTPRH,DHFR,PXMP2,TSEN15,FAM228A,RGS12,POLR1D,DHRS2,ZNF219,DRAM1,DLEU1,F10,PCBD2,FCGR3A,FNIP1,TNFRSF19,FLT1,VEZT,FBXO11,THADA,P2RX2,UGGT2,SNRPF,PDS5B,NAAA,TMEM183A,BRD8,ADGRA3,C5orf56,XPO4,LINC01551,ATP6V0A2,UBE2K,ARHGAP30,HPCAL1,ZMYM2,IRF1,KIR2DS4,NUAK2,AXDND1,LMNB1,CDK2AP1,IFT88" MicroRNA hsa-miR-664:PITA hsa-miR-664:PITA_TOP PITA 5.59E-17 2.97E-13 2.93E-16 2.68E-15 40 679 "MAP1B,SMIM15,NLN,ARL1,SLC4A4,KCTD12,NOVA1,DCLK1,PDE4D,GPR180,LYSMD3,NCOR2,LRRTM2,DNM3,MATR3,COG3,DMXL1,TBC1D4,TSEN15,RGS4,MBNL2,SPATA9,ELK3,SUCO,VEZT,PLEKHA6,CCDC88A,NR5A2,MYT1L,IQGAP2,ACSL6,EML4,BAZ1A,RIMBP2,ADAMTS19,KLF12,SLAIN1,DCP2,YTHDC2,ZBTB41" MicroRNA hsa-miR-4319:mirSVR_lowEffct hsa-miR-4319:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.71E-17 3.04E-13 2.99E-16 2.74E-15 58 1394 "ADD1,SNX24,APC,SLC4A4,ZNF542P,B4GALT3,CD84,FCRL3,CACNA1E,FCHO2,SCARB1,FCRLB,CDK17,PDGFRA,CHD1,CFAP54,NRXN1,PTPRVP,HOMER1,NCOR2,ITSN2,MPHOSPH8,ZNF586,DMXL1,TINF2,DHFR,RNF219,LATS2,KIRREL1,MPHOSPH9,GP6,ZNF219,STK32B,RELL1,FLT3,ZCCHC8,NLRP2,THADA,CHFR,CYP1B1-AS1,NFASC,ZBTB37,LPIN1,TBC1D1,UTP20,TCF7,KMT5C,KHNYN,CRB1,GPR161,BAZ1A,HMGCR,TMEM174,ANKDD1B,CAB39L,NUAK2,TTC7A,ZNF304" MicroRNA hsa-miR-214:mirSVR_highEffct hsa-miR-214:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.75E-17 3.06E-13 3.01E-16 2.76E-15 46 900 "LRRC43,SNX24,ASTN1,NFATC4,NRL,PAH,RGSL1,PDGFRA,PGGT1B,WDFY2,HOMER1,LYSMD3,CMTM5,PPP2R3C,NR1H4,TMEM161B,TMEM33,SETDB2,CWC27,STK32B,GOLGA2P5,SLC8A1,CHFR,MYT1L,PDS5B,ZNF274,NPAS3,MCCC2,PCDH17,DHRS4,ZNF544,UGT2A1,C5orf56,DOCK9,COP1,YIPF7,MAEL,HEXB,ADAMTS19,RXFP2,SLAIN1,TENT2,IL25,DCP2,IGF1,ANKS1B" MicroRNA hsa-miR-17-5p:Functional MTI Functional MTI miRTarbase 5.84E-17 3.11E-13 3.06E-16 2.80E-15 53 1181 "RALGAPA1,MCC,SMIM15,ADD1,ULK1,ARHGAP5,ARL1,PPP1R12B,BCL2L2,ARHGEF7,FCHO2,CFL2,PFKFB2,SLC25A3,GNPTAB,LYSMD3,CLOCK,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,SACS,RABGAP1L,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,NTN4,ETF1,DNAJC27,N4BP2L2,SUCO,BRMS1L,ZNF446,GAK,ERAP1,NPAS3,KLHL20,ZBTB37,LPIN1,GTF2H3,TXK,UBC,NSD2,TADA2B,ZDHHC20" MicroRNA hsa-miR-1245:mirSVR_lowEffct hsa-miR-1245:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.08E-17 3.24E-13 3.18E-16 2.91E-15 58 1396 "RALGAPA1,ABL2,MCC,BIRC6,WDR35,SEMA6A,APAF1,MSH2,NLRP4,ARHGEF7,NOVA1,AMDHD1,FCGR2C,PCDH9,PDGFRA,VIT,THAP6,STRN3,SNCAIP,ITSN2,LRRTM2,FAM169A,DNM3,UBXN2A,PTPRH,C14orf119,EGLN3,ATG10,RNASE2,GRTP1,HSD17B7,SGCG,PAICS,CGREF1,WDCP,LIMCH1,MEGF10,GABRB1,KIF21B,PDS5B,JPH4,IQGAP2,ERAP1,PCDH17,LPIN1,UGT2A1,STON1,MAEL,ADAMTS19,TXK,TENT2,NLRP8,STARD4,LHX9,KIR2DL4,KIR2DS4,RILPL2,SPATA13" MicroRNA hsa-miR-17*:mirSVR_highEffct hsa-miR-17*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.12E-17 3.26E-13 3.19E-16 2.92E-15 49 1019 "MDM4,AACS,ASTN1,NFATC4,BTF3,FCGR2C,UHMK1,SNTG2,PCK2,CDK17,RCBTB2,GPR180,LINC01085,AKAP6,GNPTAB,CSNK1G3,COCH,G3BP2,PPP2R3C,NR1I3,MPHOSPH9,NDUFAF7,PIBF1,POLK,VEZT,BRMS1L,UFM1,N4BP2,WDCP,MYO16,GABRA2,JPH4,ERAP1,CMPK2,LINC02393,MTUS2,ADGRA3,RNF17,TPO,ADAMTS19,KLF12,TECRL,HSD17B4,ZNF876P,TENT2,ZFHX2,IL6ST,ANKS1B,LHX9" MicroRNA hsa-miR-2355:mirSVR_highEffct hsa-miR-2355:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.00E-17 3.72E-13 3.65E-16 3.34E-15 42 755 "LRRC43,NLN,HOMEZ,CD84,NFATC4,SLC5A6,CAST,CCNB1,ZNF664,PDE4D,PDGFRA,RCBTB2,PGGT1B,LYSMD3,CSNK1G3,FCRL5,SPATA18,DNMT3A,LRPPRC,RNASEL,MBNL2,KLHL12,ABCA11P,GMPR2,TLR6,FCGR2B,NBEA,SLC22A5,LIMCH1,OXGR1,CMPK2,MCCC2,LRCH1,ZBTB37,PPIP5K2,GTF2H3,TMPO,IL6ST,RNASE11,TTC41P,AXDND1,PABPN1" MicroRNA hsa-let-7f:mirSVR_highEffct hsa-let-7f:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.07E-17 3.76E-13 3.68E-16 3.37E-15 44 829 "MDM4,SLAMF6,HOMEZ,BLZF1,WDR19,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RB1,RGS12,CWC27,PCGF3,FCGR2B,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,DRC1,LRCH1,BRD8,ACSL6,CRB1,HEXB,PAPPA2,ZNF10,FAM49A,SPRYD7,AXDND1" MicroRNA hsa-miR-124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.34E-17 3.90E-13 3.82E-16 3.50E-15 59 1446 "CCNA1,PNP,CAST,FCHO2,CD1D,UHMK1,FAM177A1,CEBPE,VIT,DHRS1,PGGT1B,PKP1,ANAPC4,HEATR5A,EPGN,LYSMD3,CLOCK,NGDN,ITSN2,DNM3,EIF2AK2,SNX17,PTGS2,F11R,G3BP2,FAM129A,OGFOD2,REST,RGS4,SPATA9,ELK3,MPHOSPH9,STX2,DRAM1,DLEU1,GMPR2,TMEM156,DDX51,SLC15A4,SLC22A5,PUS1,LIMCH1,SNRPF,IKBIP,SULT1E1,ZBTB37,METAP2,MTUS2,NT5C1B,GRSF1,CRB1,GPR161,TGM1,TADA2B,ANKS1B,RILPL2,TTC7A,LMNB1,LTA4H" MicroRNA hsa-miR-569:mirSVR_highEffct hsa-miR-569:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.36E-17 3.91E-13 3.82E-16 3.50E-15 48 984 "SEMA6A,HOMEZ,CUL4A,APAF1,NOVA1,SCARB1,NFXL1,RCBTB2,TAPT1,COPA,ZFYVE16,FBXL5,OCIAD1,G3BP2,PPP2R3C,NR1H4,B3GLCT,SPATA9,ELK3,DRAM1,CLIP1,UTP15,FNIP1,FGF9,PIBF1,VEZT,SLC12A2,NPAS3,RBKS,NEDD1,KLHL20,PCDH17,MIMT1,LINC02393,PPIP5K2,YIPF7,COX18,FCRLA,TFDP1,TECRL,WDR36,YTHDC2,LHX9,DNAH10,LIG4,LMNB1,CDK2AP1,SKA3" MicroRNA hsa-miR-519d-3p:Functional MTI Functional MTI miRTarbase 7.38E-17 3.92E-13 3.83E-16 3.51E-15 46 906 "MCC,ADD1,ULK1,ARL1,PPP1R12B,BCL2L2,ARHGEF7,FCHO2,CFL2,PFKFB2,GNPTAB,LYSMD3,CLOCK,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,SACS,RABGAP1L,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,ETF1,DNAJC27,N4BP2L2,SUCO,BRMS1L,ZNF446,GAK,ERAP1,KLHL20,ZBTB37,GTF2H3,TXK,UBC,NSD2,TADA2B,ZDHHC20" MicroRNA hsa-miR-140-5p:mirSVR_highEffct hsa-miR-140-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.79E-17 4.14E-13 4.04E-16 3.70E-15 45 869 "BIRC6,NCOA1,CAST,FCHO2,SNTG2,MRPL57,LINC01085,STRN3,GNPTAB,LYSMD3,SNCAIP,CSNK1G3,FCRL5,COG3,TSEN15,NTN4,MARVELD2,FCGR2B,FNIP1,FGF9,POLK,MROH9,SUPT20H,SLC34A2,MRPS14,UGGT2,GABRA2,CIDEB,RAPGEF6,OXGR1,GC,ADGRL3,GPR161,NPL,GUF1,SLAIN1,YTHDC2,JCHAIN,ZNF140,SPTSSA,ANKS1B,CHPT1,KCNN2,KIR3DL2,LMNB1" MicroRNA hsa-miR-874:mirSVR_lowEffct hsa-miR-874:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.92E-17 4.21E-13 4.11E-16 3.76E-15 60 1493 "SNX24,APAF1,ASTN1,CENPBD1P1,ATP7B,CD84,BTF3,LINC02347,CACNA1E,CBLN3,RILPL1,CD1D,NFXL1,SNTG2,VIT,GPR180,LINC01085,PIK3C2B,POLN,SNCAIP,LACC1,ITSN2,LRRTM2,BIVM,SUPT7L,DNMT3A,ZNF329,OGFOD2,RGS12,POLR1D,RNF4,LGR6,DLEU1,F10,TOMM40L,NDUFAF7,TNFRSF19,HSD17B7,THADA,ZNF605,TMEM183A,ZNF274,ERAP1,ATP8A2,OXGR1,NPAS3,LILRB1,KLHL20,ZNF544,CNTN2,ARHGEF28,FCRLA,GZMH,HSD17B4,YTHDC2,FCRL6,JCHAIN,ZBED3-AS1,KCNJ9,TTC41P" MicroRNA hsa-miR-4253:mirSVR_lowEffct hsa-miR-4253:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.31E-17 4.42E-13 4.30E-16 3.94E-15 59 1450 "SFTA3,BIRC6,ASTN1,CENPBD1P1,SLC4A4,ATP2B4,STARD13,KCTD12,BCL2L2,CD84,NFATC4,ZNF664,ZNF595,THAP6,C1orf116,EPGN,SNCAIP,FCRL5,SNX17,F11R,PTPRH,SLC35F6,PXMP2,LINC01257,DTD2,SETDB2,LRPPRC,PACRGL,RNASEL,RNF4,KIRREL1,LGR6,MARVELD2,UTP15,POLK,FOXG1,FBXO11,IVNS1ABP,TADA1,N4BP2,C1orf112,CYP1B1-AS1,KIF21B,NAAA,TMEM183A,ERAP1,CMPK2,MCCC2,UTP20,TMED2,FZD10,GUF1,YTHDC2,ZNF10,CENPH,FAM151B,KIF3C,RILPL2,LETM1" MicroRNA hsa-miR-296-3p:mirSVR_lowEffct hsa-miR-296-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.57E-17 4.56E-13 4.43E-16 4.06E-15 59 1451 "KIAA1211,NYNRIN,SEMA6A,HOMEZ,UVSSA,MSH2,NOP14,ASCL1,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,NRL,MPZL1,UHMK1,DCLK1,C1orf116,TAPT1,POU2F1,FCRL5,MATR3,COG3,NUDT12,MTX3,PPP2R3C,DNMT3A,DTD2,GUSBP3,RNASEL,TXNDC15,LGR6,DNAJC27,TOMM40L,GORAB,FNIP1,SELP,FTLP10,FBXO11,CGREF1,MEGF10,KIF21B,NMNAT2,OXGR1,LRCH1,ADGRA3,ANO4,KHNYN,RNF212,NPL,ADAMTS19,ZNF876P,ZNF470,ZNF84,SPTSSA,GALP,PGAM5,KIT,LINC01913,NUAK2" MicroRNA hsa-miR-27b-3p:TargetScan hsa-miR-27b-3p TargetScan 8.65E-17 4.60E-13 4.46E-16 4.09E-15 49 1028 "ABL2,MAP1B,MATN3,MDM4,ADD1,NLN,PITPNM2,DHX37,APAF1,FBRSL1,APC,NCOA1,ATP1A2,B4GALT3,NOVA1,CAMK4,PCDH9,CDK18,PDGFRA,NRXN1,ATAD2B,LYSMD3,ITSN2,CEP135,MBNL2,FAM172A,DNAJC27,PCGF3,FOXO1,CCDC92,PLEKHA6,MRPS14,NR5A2,GABRB1,KIF21B,PDS5B,NPAS3,NFASC,LPIN1,INSM2,GRSF1,KLF12,HMGCR,PAPPA2,DCP2,IGF1,C12orf73,IL6ST,LOX" MicroRNA hsa-miR-27a-3p:TargetScan hsa-miR-27a-3p TargetScan 8.65E-17 4.60E-13 4.46E-16 4.09E-15 49 1028 "ABL2,MAP1B,MATN3,MDM4,ADD1,NLN,PITPNM2,DHX37,APAF1,FBRSL1,APC,NCOA1,ATP1A2,B4GALT3,NOVA1,CAMK4,PCDH9,CDK18,PDGFRA,NRXN1,ATAD2B,LYSMD3,ITSN2,CEP135,MBNL2,FAM172A,DNAJC27,PCGF3,FOXO1,CCDC92,PLEKHA6,MRPS14,NR5A2,GABRB1,KIF21B,PDS5B,NPAS3,NFASC,LPIN1,INSM2,GRSF1,KLF12,HMGCR,PAPPA2,DCP2,IGF1,C12orf73,IL6ST,LOX" MicroRNA hsa-miR-1225-5p:mirSVR_lowEffct hsa-miR-1225-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.95E-17 4.76E-13 4.62E-16 4.23E-15 48 989 "CADM3,BCL2L2,CACNA1E,RILPL1,CDK18,PFKFB2,COLEC11,PIGR,HOMER1,THTPA,TTC37,UBXN2A,TBC1D4,RABGAP1L,MEMO1,EFNA5,MBNL2,STX2,DRAM1,DNAJC27,FLT1,SLC34A2,G2E3,BRMS1L,CCDC88A,YPEL5,CENPJ,EAPP,KDM3B,NFASC,NEDD1,STRN,UTP20,PPIP5K2,MTUS2,ARHGEF28,RNF212,TDG,NCSTN,CRB1,LINC01551,TMPO,ADAMTS19,LTB4R2,WDR36,MZF1,KIT,TTC41P" MicroRNA hsa-miR-574-5p:mirSVR_highEffct hsa-miR-574-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.24E-17 4.91E-13 4.76E-16 4.36E-15 42 761 "WDR19,CD1D,PDGFRA,RCBTB2,THAP6,NCOR2,DCAF8,PIGG,DMXL1,COCH,TSEN15,AASDH,POLR1D,RNASE2,RNASEL,ARSK,CWC27,PCGF3,USP44,FNIP1,SUPT20H,NLRP2,LRCH1,MAST4,ANO4,C5orf56,NT5C1B,TXK,IL25,NSD2,IL6ST,PLB1,ZMYM2,NPHS2,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,LINC01913,LINC00442,ZDHHC20" MicroRNA hsa-miR-648:mirSVR_lowEffct hsa-miR-648:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.27E-17 4.93E-13 4.77E-16 4.37E-15 55 1279 "SFTA3,MAP1B,TMEM132B,NLN,WDR35,APC,WDR19,ARHGAP5,ASTN1,ATP12A,CD84,NFATC4,NFKBIA,PCK2,PFKFB2,CHIT1,CPNE6,PTPRVP,AKAP6,CLOCK,C12orf65,LRRTM2,FCRL5,ZNF586,COCH,SUPT7L,ZNF329,PACRGL,MBNL2,KLHL12,GP6,PCGF3,FOXO1,FLT1,STAB2,IVNS1ABP,ARHGEF40,DCAF11,MYO16,ATP8A2,NFASC,IKBIP,KMT5A,TDG,TGFBI,TGM1,ADAMTS19,WDR36,PLB1,KIT,EP400P1,RMST,TTC7A,AXDND1,SPATA13" MicroRNA hsa-miR-873:mirSVR_highEffct hsa-miR-873:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.31E-17 4.95E-13 4.79E-16 4.38E-15 48 990 "MATN3,CUL4A,ATP7B,ARHGEF7,SLC5A6,CAST,PAH,PDGFRA,SLC25A3,COLEC11,MPC2,GNPTAB,PRKD1,ZFYVE16,MATR3,SNX17,BIVM,NUDT12,TSEN15,RNF219,EGLN3,RB1,ARGLU1,RGS12,MBNL2,KIRREL1,KLHL12,BORA,UTP15,TOMM40L,FCGR3B,PIBF1,MROH9,FOXO1,NUBPL,LIMCH1,RAPGEF6,NAAA,HSPH1,DRC1,ADGRL3,BAZ1A,KCNT2,IL6ST,ZMYM2,ZBED3-AS1,LETM1,ZDHHC20" MicroRNA hsa-miR-221:mirSVR_highEffct hsa-miR-221:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.33E-17 4.96E-13 4.79E-16 4.39E-15 49 1030 "RALGAPA1,ABL2,MAP1B,WDR35,PITPNM2,APAF1,WDR19,NOVA1,LDB2,UHMK1,CDK18,PFKFB2,ZNF595,GPR180,ATAD2B,POU2F1,KIAA0040,ZFYVE16,NUDT12,SUPT7L,TSEN15,NTN4,MARVELD2,PCGF3,FGF9,PIBF1,POLK,FBXO11,CCDC88A,PKD2L2,SF3B6,MYT1L,CMPK2,PPARGC1A,BRD8,ADAM17,COX7B2,PPIP5K2,ZBTB49,TMPO,RIMBP2,MAEL,TXK,GUF1,SLAIN1,SPTSSA,KIR3DL1,KIT,LMNB1" MicroRNA hsa-miR-3134:mirSVR_lowEffct hsa-miR-3134:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.56E-17 5.09E-13 4.91E-16 4.50E-15 56 1323 "TMEM132B,RGS5,APC,BLZF1,ATP2B4,STARD13,KCTD12,BCL2L2,FCRL3,NFATC4,NOVA1,PDGFRA,ATAD2B,HEATR5A,CLOCK,NCOR2,DNM3,FCRL2,GLT8D2,NUDT12,MTX3,SUPT7L,PARPBP,FAM129A,ATG10,PACRGL,LATS2,RNF4,MBNL2,TRAPPC12,RELL1,PIBF1,HSD17B7,FBXO11,SLC12A2,POTEM,TMEM132D,ACIN1,MEGF10,NAAA,METAP2,ADGRL3,C1QTNF9B,GPR161,NPL,SLAIN1,TENT2,HTR2A,YTHDC2,IGF1,JCHAIN,LHX9,FAM151B,KIF2A,LINC00442,LOX" MicroRNA hsa-miR-1972:mirSVR_highEffct hsa-miR-1972:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.68E-17 5.15E-13 4.96E-16 4.54E-15 42 762 "NLN,CUL4A,CD84,BTF3,FCHO2,SNTG2,PCCA,PDE4D,PDGFRA,SMIM14,DNM3,NOS1AP,FCRL2,SPATA18,PSME1,F11R,RNF219,RAN,FAM129A,ATG10,TMEM161B,RGS4,EIF2D,FAM172A,ETF1,POLK,NUBPL,MYO16,JPH4,NAAA,ZNF274,NPAS3,ZNF544,BAZ1A,RASSF6,ADAMTS19,STARD4,ZNF10,ZMYM2,TTC41P,AXDND1,IFT88" MicroRNA hsa-miR-125b:mirSVR_lowEffct hsa-miR-125b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.99E-17 5.31E-13 5.12E-16 4.69E-15 59 1456 "ADD1,SNX24,APC,SLC4A4,ZNF542P,B4GALT3,CACNA1E,FCHO2,SCARB1,FCRLB,CDK17,PDGFRA,CHD1,CFAP54,NRXN1,PTPRVP,HOMER1,FAM53A,NCOR2,ITSN2,MPHOSPH8,NOS1AP,ZNF586,DMXL1,TINF2,DHFR,LATS2,KIRREL1,MPHOSPH9,GP6,ZNF219,STK32B,FLT3,ZCCHC8,NLRP2,THADA,CHFR,CYP1B1-AS1,NFASC,IKBIP,ZBTB37,LPIN1,TBC1D1,UTP20,LINC02393,TCF7,KMT5C,KHNYN,TDG,CRB1,GPR161,BAZ1A,HMGCR,TMEM174,ANKDD1B,CAB39L,NUAK2,TTC7A,ZNF304" MicroRNA hsa-miR-641:PITA hsa-miR-641:PITA_TOP PITA 1.00E-16 5.32E-13 5.13E-16 4.69E-15 34 490 "MAP1B,BIRC6,FAM193A,ODC1,FCHO2,UHMK1,PCDH9,CDK17,STRN3,CSNK1G3,SREK1,MTX3,ELF1,ETF1,DNAJC27,CLIP1,USP44,FNIP1,FOXO1,NR5A2,MYT1L,NPAS3,SRP72,ERBIN,PCDH17,PPIP5K2,KMT5A,GRSF1,BAZ1A,UBE2K,TXK,ZNF470,ZBTB41,KIT" MicroRNA hsa-miR-520d-5p:PITA hsa-miR-520d-5p:PITA_TOP PITA 1.07E-16 5.68E-13 5.46E-16 5.00E-15 46 915 "ADD1,EP400,NCOA1,ODC1,FCHO2,PCDH9,ZNF595,GPR180,NUP37,ATAD2B,BOD1L1,HECTD1,CRHBP,CSNK1G3,MATR3,CEP350,TBC1D4,FAM129A,ARGLU1,TMEM161B,CLIP4,MBNL2,KLHL12,PCGF3,FNIP1,SUCO,FOXO1,G2E3,NBEA,CCDC88A,SLC12A2,NR5A2,MYO16,MYT1L,PDS5B,LRCH1,ERBIN,KLHL20,PSME4,KMT5A,RIMBP2,POC5,SPTSSA,TMEM178A,KIF2A,CDK2AP1" MicroRNA hsa-miR-524-5p:PITA hsa-miR-524-5p:PITA_TOP PITA 1.07E-16 5.68E-13 5.46E-16 5.00E-15 46 915 "ADD1,EP400,NCOA1,ODC1,FCHO2,PCDH9,ZNF595,GPR180,NUP37,ATAD2B,BOD1L1,HECTD1,CRHBP,CSNK1G3,MATR3,CEP350,TBC1D4,FAM129A,ARGLU1,TMEM161B,CLIP4,MBNL2,KLHL12,PCGF3,FNIP1,SUCO,FOXO1,G2E3,NBEA,CCDC88A,SLC12A2,NR5A2,MYO16,MYT1L,PDS5B,LRCH1,ERBIN,KLHL20,PSME4,KMT5A,RIMBP2,POC5,SPTSSA,TMEM178A,KIF2A,CDK2AP1" MicroRNA hsa-miR-518c*:mirSVR_highEffct hsa-miR-518c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-16 5.80E-13 5.57E-16 5.10E-15 52 1157 "AACS,ARHGEF7,CDKL2,TAF1B,CD1E,PCDH9,PCK2,PDGFRA,VIT,LTB4R,PM20D1,POU2F1,DMXL1,C14orf119,TSEN15,RNF219,DNMT3A,RASA1,FAM228A,IPO4,RGS12,PACRGL,STX2,FAM172A,DRAM1,EFS,TMEM156,FCGR2B,TOMM40L,GORAB,N4BP2L2,PIBF1,BRMS1L,NUBPL,POTEM,LIMCH1,KIF21B,JPH4,HSPH1,NPAS3,LRCH1,ERBIN,GPR12,CRB1,TGFBI,GPR161,LINC01551,BAZ1A,NPL,HEXB,EP400P1,SLAMF9" MicroRNA hsa-miR-4274:mirSVR_highEffct hsa-miR-4274:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-16 5.87E-13 5.63E-16 5.16E-15 36 556 "BIRC6,SLC4A4,BTF3,CACNA1E,CAMK4,PCDH9,CLOCK,VCAN,DNM3,DCAF8,PIGG,PTGS2,COCH,CEP120,TSEN15,RAN,EGLN3,RNF31,NTN4,TRAPPC12,ETF1,FGF9,FGFR3,FOXG1,VEZT,RUBCNL,KIF21B,GJB6,PSME4,ANO4,ACSL6,KMT5C,NT5C1B,ANKS1B,CHPT1,RMST" MicroRNA hsa-miR-20b-5p:Functional MTI Functional MTI miRTarbase 1.16E-16 6.17E-13 5.91E-16 5.41E-15 46 917 "MCC,ADD1,ULK1,ARL1,PPP1R12B,BCL2L2,ARHGEF7,FCHO2,CFL2,PFKFB2,GNPTAB,LYSMD3,CLOCK,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,SACS,RABGAP1L,SLC35F6,WDR1,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,ETF1,DNAJC27,N4BP2L2,SUCO,BRMS1L,ZNF446,GAK,ERAP1,KLHL20,ZBTB37,GTF2H3,TXK,UBC,NSD2,TADA2B,ZDHHC20" MicroRNA hsa-miR-3190-3p:mirSVR_highEffct hsa-miR-3190-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-16 6.33E-13 6.06E-16 5.55E-15 44 841 "RALGAPA1,MAP1B,ADD1,SLAMF6,ASTN1,ARHGEF7,PAH,PCK2,PDGFRA,PFKFB2,RNASE9,PM20D1,PSME1,NUDT12,WDR1,ARGLU1,CLIP4,MEMO1,SETDB2,RNASEL,GORAB,SUCO,PEAR1,FLT3,MBIP,UFM1,CHFR,MYT1L,CIDEB,METAP2,C5orf56,RNF212,GZMH,HAL,IGSF8,NSD2,DCP2,IL6ST,PLB1,TDRD3,ZBED3-AS1,KIT,RILPL2,PABPN1" MicroRNA hsa-miR-4310:mirSVR_highEffct hsa-miR-4310:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.37E-16 7.27E-13 6.95E-16 6.36E-15 56 1334 "MAP1B,KIAA1211,CDKL4,NOVA1,DAOA,FCHO2,CD1E,CDK7,RGSL1,PDE4D,GPR180,GNPTAB,SNCAIP,VCAN,DNM3,ZNF586,ZFYVE16,PTGS2,DMXL1,TBC1D4,G3BP2,GNPDA2,PPP2R3C,ARGLU1,ZNF329,EFNA5,TXNDC15,MBNL2,DCUN1D2,GORAB,FNIP1,FLT1,HSD17B7,CCDC88A,C1orf112,EFR3B,MYT1L,CIDEB,KDM5B,NPAS3,PPARGC1A,ADGRL3,ADGRA3,TDG,ZBTB49,GPN1,GUF1,WDR36,ZNF10,TADA2B,ZNF140,ZMYM2,KIR2DS4,TTC41P,LINC01913,RMST" MicroRNA hsa-miR-30a-5p:Functional MTI Functional MTI miRTarbase 1.43E-16 7.59E-13 7.25E-16 6.64E-15 41 734 "SEMA6A,NOP14,CAST,CHD1,PGGT1B,WDFY2,PIK3C2B,HECTD1,PREPL,CSNK1G3,CEP350,TBC1D4,SACS,MTX3,MBNL2,TRIM28,EIF2B1,FAM81B,UTP15,FOXG1,TM9SF1,RUBCNL,PAICS,UFM1,SLC12A2,N4BP2,LIMCH1,CPSF3,ATP8A2,IKBIP,STRN,PSME4,TMED2,EML4,NT5C1B,TFDP1,TGFBI,SELENOI,LCP1,ZDHHC20,LOX" MicroRNA hsa-miR-1911:mirSVR_highEffct hsa-miR-1911:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-16 8.02E-13 7.65E-16 7.00E-15 27 294 "CAST,SNX6,MPHOSPH8,EIF2AK2,NR1H4,PACRGL,TXNDC15,MBIP,IVNS1ABP,WDCP,SLC22A5,GABRB1,KDM5B,IQGAP2,MCCC2,GJB2,KMT5A,TEP1,RASSF6,RIMBP2,MAEL,HEXB,FAM151B,CHPT1,KCNN2,KIR2DL4,AXDND1" MicroRNA hsa-miR-298:PITA hsa-miR-298:PITA_TOP PITA 1.58E-16 8.41E-13 8.02E-16 7.34E-15 26 269 "MAP1B,NDRG2,SEMA6A,APBB2,NCOA1,MYBPC1,BCL2L2,FCHO2,PCCA,ATAD2B,LRRTM2,BIVM,G3BP2,DNMT3A,TMEM33,ELF1,DNAJC27,TMEM129,FBXO11,CCDC88A,PCDH17,PPARGC1A,INSM2,ADGRL3,XPO4,TDRD3" MicroRNA hsa-miR-1261:mirSVR_highEffct hsa-miR-1261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-16 8.50E-13 8.10E-16 7.41E-15 48 1004 "ARHGAP5,ASTN1,PAH,RGSL1,PDGFRA,CFL2,CCDC122,SLC25A3,NRXN1,THAP6,HOMER1,STRN3,VCAN,FCRL5,SPATA18,COG3,NUDT12,PTPRC,RABGAP1L,SUPT7L,RNF219,RASA1,RGS4,RNASEL,LATS2,DHRS2,FAM172A,F7,FCGR3B,FNIP1,POLK,VEZT,NBEA,CCDC92,STPG4,CCDC88A,SLC22A4,KDM5B,GJB6,KDM3B,ERBIN,IKBIP,METAP2,CRB1,ADAMTS19,IL25,NSD2,ZNF470" MicroRNA hsa-miR-1322:mirSVR_highEffct hsa-miR-1322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-16 8.73E-13 8.31E-16 7.60E-15 41 737 "COG6,WDR35,SNX24,NCOA1,NEDD8,CACNA1E,PCCA,JAKMIP1,CRHBP,NGDN,LACC1,ZNF586,PACRGL,TXNDC15,MARVELD2,DRAM1,CWC27,SAP18,USP44,TRAPPC13,PCBD2,PIBF1,POLK,IVNS1ABP,CCDC88A,MEGF10,RBKS,MIMT1,TCF7,KMT5A,TDG,TGFBI,ADAMTS19,SLAIN1,POC5,VRK2,HTR2A,DIAPH3,TTC41P,AXDND1,IFT88" MicroRNA hsa-miR-134:mirSVR_highEffct hsa-miR-134:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.99E-16 1.06E-12 1.01E-15 9.21E-15 40 705 "WDR35,BLZF1,FCGR2C,WDFY2,MRPL57,ITGBL1,THAP6,COPA,LYSMD3,SNCAIP,KIAA0040,FCRL5,RAN,DTD2,PACRGL,TBC1D19,ETF1,USP44,N4BP2L2,TNFRSF19,FOXG1,CCDC92,ZNF605,SLC15A4,CYP1B1-AS1,ERAP1,NFASC,ANO4,EML4,RNF212,RNF17,RAB2B,MAEL,ZNF550,SLAIN1,MZF1,ZMYM2,IRF1,CHPT1,AXDND1" MicroRNA hsa-miR-143*:mirSVR_highEffct hsa-miR-143*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-16 1.11E-12 1.05E-15 9.64E-15 40 706 "APC,NCOA1,CD84,NFKBIA,LDB2,FCGR2C,CDK17,CENPC,WDFY2,LINC01085,ATAD2B,RCHY1,GNPTAB,FCRL5,SACS,FAM228A,MEMO1,RNF4,ELF1,MPHOSPH9,DHRS2,ARSK,CCDC88A,MYT1L,GABRB1,TMEM183A,CD244,NPAS3,LRCH1,GJA3,STRN,MTUS2,ANO4,C1QTNF9B,TFDP1,CRB1,NSD2,C12orf73,PLB1,KCNN2" MicroRNA hsa-miR-1258:mirSVR_highEffct hsa-miR-1258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-16 1.11E-12 1.05E-15 9.64E-15 40 706 "ANKRD34B,TBC1D14,WDR35,ASCL1,PCK2,PCSK1,RGSL1,ITGBL1,GNPTAB,VCAN,COCH,SUPT7L,NR1H4,TMEM161B,REST,DTD2,LATS2,TRAPPC12,ARSK,CWC27,ABCA11P,IVNS1ABP,SLC22A5,MRPS14,CYP1B1-AS1,KDM5B,NPFFR2,PPARGC1A,GJB2,SCFD1,DOCK9,TDG,RNF17,FZD10,TECRL,STARD4,KCNN2,FIP1L1,LINC01913,SPATA13" MicroRNA hsa-miR-3189:mirSVR_lowEffct hsa-miR-3189:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-16 1.12E-12 1.06E-15 9.69E-15 61 1571 "MATN3,KIAA1211,ARL1,ATP2B4,STARD13,ARHGEF7,BTF3,ADGRD1,PCDH9,RCBTB2,PGGT1B,PKP1,JAKMIP1,POLN,STRN3,PM20D1,ITSN2,UBXN2A,DGKQ,PIGG,PTPRH,PARPBP,C14orf119,AASDH,RNF4,MBNL2,ZNF219,ADGRV1,GMPR2,SLC22A17,ARL6IP4,TOMM40L,SPON2,FNIP1,N4BP2L2,RELL1,FOXG1,PEAR1,VEZT,NR5A2,UGGT2,PDS5B,RAPGEF6,HSPH1,MIMT1,UTP20,ANO4,STON1,FCRLA,CRB1,ACTR6,RIMBP2,ATP6V0A2,KLF12,ZFHX2,ZNF470,PGAM5,CHPT1,SLAMF9,RMST,AXDND1" MicroRNA hsa-miR-2116:mirSVR_highEffct hsa-miR-2116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.27E-16 1.21E-12 1.14E-15 1.05E-14 52 1178 "ABL2,COG6,NCOA1,STARD13,ARHGEF7,CD1E,PFKFB2,TSTD1,LINC01085,LTB4R,HECTD1,POU2F1,PREPL,ZNF586,MATR3,LOC439933,NUDT12,CEP120,DHFR,PARPBP,PPP2R3C,RASA1,DTD2,TBC1D19,MAEA,CLIP1,UTP15,POLK,FOXO1,VEZT,G2E3,PAICS,GFM2,THADA,CCDC88A,SLC12A2,PKD2L2,C1orf112,MYT1L,PDS5B,NAAA,SRP72,PCDH17,GJA3,ADGRL3,STON1,TECRL,JCHAIN,ZNF470,CCDC169,LMLN,SKA3" MicroRNA hsa-miR-1237:mirSVR_highEffct hsa-miR-1237:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-16 1.25E-12 1.18E-15 1.08E-14 43 819 "TBC1D14,DDX55,ASTN1,KCTD12,NOVA1,FCHO2,PCCA,CDK18,CCDC122,LTB4R,FAM53A,HEATR5A,FCRL2,BIVM,FBXL5,G3BP2,CLIP4,TXNDC15,ZNF671,TRAPPC13,FOXG1,HSD17B7,ARHGEF40,ZNF605,KIF21B,JPH4,MRPS27,KLHL20,MIMT1,ZBTB37,LINC02393,ANO4,C5orf56,ZNF550,PAPPA2,STARD4,PGAM5,LHX9,KCNN2,RILPL2,LMNB1,PABPN1,MICU2" MicroRNA hsa-miR-153:mirSVR_highEffct hsa-miR-153:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.40E-16 1.28E-12 1.21E-15 1.10E-14 45 896 "RALGAPA1,KIAA1211,EP400,APC,AACS,SLC4A4,NOVA1,MPZL1,CDK17,CFL2,VIT,NUP37,BOD1L1,AKAP6,RCHY1,ITSN2,CEP135,FAM169A,SPATA18,CEP350,KLHL3,G3BP2,GNPDA2,RNF219,RASA1,AASDH,LAP3,TBC1D19,DNAJC27,ABCA11P,SH3YL1,TMEM156,TOMM40L,NBEA,UFM1,ARHGEF40,NR5A2,GABRB1,ERAP1,LRCH1,PSME4,GTF2H3,UBE2K,TECRL,TMEM178A" MicroRNA hsa-miR-1291:mirSVR_lowEffct hsa-miR-1291:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-16 1.29E-12 1.22E-15 1.12E-14 61 1576 "MAP1B,LRRC43,TBC1D14,ATP4B,BCL2L2,NFATC4,SLC5A6,RGSL1,ZNF595,FAM163A,GNPTAB,POU2F1,SNCAIP,ITSN2,FCRL5,NOS1AP,SNX17,EPS8L1,PIGG,C12orf42,TSEN15,RNF219,NR1I3,NR1H4,OGFOD2,EMC9,RGS12,DHRS2,F10,TOMM40L,SPON2,FGFR3,SDC1,FLT3,PLEKHA6,SLC8A1,CGREF1,ACIN1,MYO16,NMNAT2,NFASC,ANKLE2,TMED2,KMT5C,CRB1,TNR,TPO,UBE2K,JCHAIN,PLB1,IRF1,KIF3C,KIR2DL4,EP400P1,TTC41P,LAD1,MFSD2B,LINC00442,LETM1,NUAK2,PABPN1" MicroRNA hsa-miR-378b:mirSVR_lowEffct hsa-miR-378b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-16 1.31E-12 1.24E-15 1.13E-14 60 1531 "ADORA1,ANKRD34B,CENPBD1P1,CCNA1,LINC02347,MPZL1,SNTG2,ZNF664,PCDH9,DCLK1,XPR1,WDFY2,MRPL57,CLOCK,SNCAIP,UBXN2A,DHFR,NR1H4,GALNT14,FAM129A,RNF31,RASA1,RB1,ZNF419,SETDB2,MBNL2,KLHL12,ABCA11P,SLC22A17,FCGR3B,TACC3,SUCO,FOXO1,DDX51,PAICS,ARHGEF40,WDCP,ACIN1,NMNAT2,RAPGEF6,UHRF1BP1L,NFASC,MCCC2,IKBIP,GJA3,ANO4,TCF7,TEP1,GRSF1,BAZ1A,RAB2B,KCNT2,ZNF324B,CCDC169,PLB1,LHX9,EP400P1,TTC41P,LETM1,RMST" MicroRNA hsa-miR-653-5p:TargetScan hsa-miR-653-5p TargetScan 2.73E-16 1.45E-12 1.37E-15 1.26E-14 32 444 "MDM4,CUL4A,APC,ARHGAP5,PPP1R3E,NOVA1,CDKL2,CAMK4,CAST,CHD1,CLOCK,F11R,REST,ELF1,SAP18,ETF1,PCBD2,FNIP1,SCYL2,MRPS14,MYT1L,KDM5B,NMNAT2,ATP8A2,PPARGC1A,GRSF1,GPR161,RAB2B,IGF1,IL6ST,KIF2A,LOX" MicroRNA hsa-miR-4266:mirSVR_lowEffct hsa-miR-4266:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-16 1.46E-12 1.38E-15 1.26E-14 57 1400 "LRRC43,KIAA1211,PITPNM2,EP400,ZNF784,SLC4A4,CARMIL3,FCRL3,NRL,CAST,RILPL1,SNTG2,MRPL57,CPNE6,AKAP6,C12orf65,PIGG,COG3,DCT,EGLN3,FAM129A,OGFOD2,MEMO1,NTN4,PACRGL,MBNL2,DHRS2,PCOTH,FCGR3A,FCGR3B,FNIP1,LRRN2,PEAR1,FLT1,FMO1,ZCCHC8,MBIP,THADA,TADA1,MRPS14,KIF21B,RAPGEF6,UTP20,ADGRL3,RNF212,COP1,TMPO,FZD10,MAEL,TNR,NPL,MZF1,ZNF84,LINC01913,LCP1,LINC00442,LOX" MicroRNA hsa-miR-28-3p:mirSVR_highEffct hsa-miR-28-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.85E-16 1.52E-12 1.43E-15 1.31E-14 41 749 "MSH2,ARL1,AMDHD1,LTB4R,HECTD1,VCAN,SREK1,CEP350,CEP120,SACS,G3BP2,PARPBP,NR1I3,RASA1,SLC9C2,POLR1D,LATS2,TRAPPC12,TBC1D19,PCGF3,ELOVL7,GORAB,FNIP1,PLEKHA6,GABRB1,FAM114A1,JPH4,RAPGEF6,NAAA,UHRF1BP1L,ERAP1,ADAM17,GTF3C2,TPO,HMGCR,ZNF10,CCDC169,SPTSSA,ANKS1B,KIT,PABPN1" MicroRNA hsa-miR-138:mirSVR_highEffct hsa-miR-138:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.90E-16 1.54E-12 1.45E-15 1.33E-14 44 862 "SLAMF6,NYNRIN,MSH2,NOP14,STXBP6,ATP4B,CAST,THAP6,SNCAIP,C12orf65,FAM169A,DNM3,MPHOSPH8,SNX17,OCIAD1,NR1H4,PACRGL,GRTP1,TRIM28,LGR6,MAEA,CLIP1,TNFRSF19,POLK,NBEA,CCDC88A,SLC22A5,YPEL5,LIMCH1,MEGF10,ALLC,NFASC,ZBTB37,PPARGC1A,MAST4,MTUS2,COX18,CRB1,LINC01551,NPL,ZBED3-AS1,ANKDD1B,FIP1L1,RMST" MicroRNA hsa-miR-587:PITA hsa-miR-587:PITA_TOP PITA 2.97E-16 1.58E-12 1.48E-15 1.36E-14 31 415 "ARL1,SLC4A4,ATP2B4,ODC1,FCHO2,PCDH9,PDE4D,CSNK1G3,PRKD1,SREK1,CEP350,FNIP1,TNFRSF19,FOXO1,G2E3,TADA1,SLC12A2,ACIN1,MYT1L,PDS5B,NMNAT2,HSPH1,ERBIN,INSM2,EML4,ADAMTS19,KLF12,SLAIN1,NSD2,ZNF10,ZMYM2" MicroRNA hsa-miR-18a*:mirSVR_highEffct hsa-miR-18a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.02E-16 1.61E-12 1.51E-15 1.38E-14 39 678 "NDRG2,HOMEZ,NOVA1,MPZL1,RILPL1,FCHO2,LDB2,NFXL1,PDGFRA,ADGRF3,THAP6,SNCAIP,COG3,DHFR,B3GLCT,SMC6,MEMO1,NTN4,SETDB2,FCAMR,USP44,BRMS1L,THADA,SLC12A2,WDCP,KLHL20,BRD8,ANO4,GPR161,ZBTB49,AP4S1,TMPO,RIMBP2,KLF12,GUF1,LINC00272,CAB39L,LCP1,AXDND1" MicroRNA hsa-miR-34a:mirSVR_highEffct hsa-miR-34a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.04E-16 1.62E-12 1.51E-15 1.39E-14 43 825 "SMIM15,MDM4,BIRC6,COG6,BLZF1,NCOA1,NFATC4,ARHGEF7,CDKL2,RILPL1,FCHO2,CDK18,PDGFRA,CHD1,SMIM14,JAKMIP1,HECTD1,AKAP6,STRN3,PREPL,DNM3,NOS1AP,COG3,PPP2R3C,SMC6,RNASEL,SUCO,FOXG1,WDCP,CMPK2,LRCH1,ANO4,DOCK9,TGFBI,TNR,GPN1,TUBA3C,CCDC169,PLB1,LINC00272,CHPT1,KIT,ZNF304" MicroRNA hsa-miR-494-3p:TargetScan hsa-miR-494-3p TargetScan 3.11E-16 1.65E-12 1.55E-15 1.42E-14 32 446 "MCC,MDM4,CUL4A,APC,ARHGAP5,PPP1R3E,NOVA1,CAST,DCLK1,PCSK1,PDGFRA,CHD1,LYSMD3,CLOCK,F11R,G3BP2,ELF1,SAP18,FBXO11,BRMS1L,KDM5B,NMNAT2,ATP8A2,NPAS3,PPARGC1A,RAB2B,DCP2,IGF1,IL6ST,ANKS1B,KIF2A,KIT" MicroRNA hsa-miR-1270:mirSVR_highEffct hsa-miR-1270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-16 1.70E-12 1.59E-15 1.46E-14 49 1063 "ANKRD34B,APAF1,ATP12A,STARD13,PNP,CDK17,RCBTB2,VIT,LYSMD3,NGDN,VCAN,ITSN2,CEP135,DMXL1,ATG10,TMEM161B,AASDH,MEMO1,RNF4,MBNL2,MPHOSPH9,CWC27,FCAR,LRRN2,NUBPL,TADA1,PKD2L2,SLC22A4,NR5A2,LIMCH1,MYO16,GABRA2,TMEM183A,CMPK2,SRP72,SULT1E1,PPARGC1A,STRN,GPR12,RNF212,RAB2B,RXFP2,VRK2,ZNF84,ZMYM2,LINC00272,RNASE11,RMST,AXDND1" MicroRNA hsa-miR-508-5p:mirSVR_highEffct hsa-miR-508-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-16 1.77E-12 1.66E-15 1.52E-14 39 680 "CAST,LDB2,SLC5A8,ZMYM5,PCSK1,GLT1D1,PIWIL1,NUP37,THAP6,ITSN2,DNM3,FCRL5,ZFYVE16,COG3,DMXL1,DNMT3A,EGLN3,GORAB,FOXO1,FLT3,VEZT,FBXO11,GABRB1,UHRF1BP1L,IQGAP2,DRC1,MCCC2,ZBTB37,ATP11A,PPIP5K2,CRB1,TGM1,HEXB,ADAMTS19,GALP,FAM49A,LCP1,RMST,AXDND1" MicroRNA hsa-miR-609:mirSVR_lowEffct hsa-miR-609:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-16 1.81E-12 1.69E-15 1.55E-14 48 1024 "RALGAPA1,MAP1B,KIAA1211,NLN,PITPNM2,BLZF1,ATP2B4,DAOA,CAST,AMDHD1,CD1D,RFLNA,PCK2,TM9SF2,POU2F1,LYSMD3,KIAA0040,PIGG,SREK1,CEP350,SLC35F6,NR1I3,NR1H4,DNMT3A,B3GLCT,RNF31,ZNF419,KIRREL1,STX2,ETF1,CLIP1,TMEM129,SUPT20H,RUBCNL,SLC8A1,SLC22A4,MYT1L,LILRB1,SULT1E1,GRSF1,MAEL,ZFHX2,ZNF470,ZNF84,KCNJ9,KCNN2,LOX,SPATA13" MicroRNA hsa-miR-601:mirSVR_lowEffct hsa-miR-601:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.45E-16 1.84E-12 1.71E-15 1.57E-14 45 905 "SMIM15,ARHGAP5,CCDC181,CAST,PCDH9,PCK2,SCFD2,PDGFRA,CFL2,HOMER1,AKAP6,LYSMD3,CEP135,KIAA0040,DCAF8,MATR3,SPATA18,GNPDA2,SUPT7L,AASDH,EIF2B1,MARVELD2,DHRS2,ARSK,PCGF3,PIBF1,FOXG1,STAB2,FBXO11,MRPS14,SNRPF,GABRA2,CENPJ,MRPS27,NFASC,IKBIP,STRN,ADGRA3,ANO4,GPR12,ADAMTS19,TMEM174,SLAIN1,MZF1,CHPT1" MicroRNA hsa-miR-101:PITA hsa-miR-101:PITA_TOP PITA 3.49E-16 1.85E-12 1.73E-15 1.58E-14 33 479 "PPFIA4,KCTD12,NOVA1,UHMK1,CDK18,PDE4D,PIK3C2B,CSNK1G3,PTGS2,CEP350,G3BP2,RABGAP1L,RNF219,DNMT3A,TMEM161B,DTD2,MPHOSPH9,SAP18,FGFR3,FOXO1,CCDC88A,SLC12A2,TMEM132D,PDS5B,KDM3B,ERBIN,XPO4,TDG,GRSF1,RIMBP2,ZMYM2,ZBTB41,LMNB1" MicroRNA hsa-miR-21-5p:Functional MTI Functional MTI miRTarbase 3.50E-16 1.86E-12 1.73E-15 1.58E-14 37 611 "MDM4,PPFIA4,APAF1,APC,MSH2,DDX55,ATP2B4,FGFRL1,PFKFB2,ATAD2B,HECTD1,CLOCK,PREPL,ITSN2,DCAF8,ZFYVE16,SREK1,RASA1,RB1,REST,CLIP4,ELOVL7,FOXO1,FBXO11,NBEA,NUBPL,IVNS1ABP,ZNF667,LIMCH1,DCAF11,RAPGEF6,NCSTN,TGFBI,MSH6,NSD2,ZMYM2,CDK2AP1" MicroRNA hsa-miR-1287:mirSVR_highEffct hsa-miR-1287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.58E-16 1.90E-12 1.77E-15 1.62E-14 41 754 "MSH2,BLZF1,CCNB1IP1,KCTD12,CBLN3,FCGR2C,RGSL1,ITGBL1,ADGRF3,LTB4R,HOMER1,SPATA18,SREK1,PTPRC,OCIAD1,DHFR,SUPT7L,C14orf119,NR1I3,RASA1,LAP3,GUSBP3,SNORA53,LGR6,FAM172A,CWC27,ABCA11P,NDUFAF7,VEZT,FBXO11,MBIP,TMEM183A,KMT5C,TGFBI,LINC01551,MAEL,TECRL,TXK,KCNT2,TTC41P,LIG4" MicroRNA hsa-miR-374b-5p:TargetScan hsa-miR-374b-5p TargetScan 3.77E-16 2.01E-12 1.86E-15 1.71E-14 35 545 "NLN,MCFD2,APC,ARHGAP5,ASCL1,NCOA1,NOVA1,DCLK1,PDE4D,HECTD1,AKAP6,FAM169A,COG3,DMXL1,CEP350,DNMT3A,RASA1,CLIP4,MBNL2,PCGF3,ELOVL7,FNIP1,FGF9,FOXG1,FOXO1,ARHGEF40,N4BP2,MYT1L,HSPH1,PPARGC1A,ACSL6,GPR161,PAPPA2,DCP2,LMLN" MicroRNA hsa-miR-374a-5p:TargetScan hsa-miR-374a-5p TargetScan 3.77E-16 2.01E-12 1.86E-15 1.71E-14 35 545 "NLN,MCFD2,APC,ARHGAP5,ASCL1,NCOA1,NOVA1,DCLK1,PDE4D,HECTD1,AKAP6,FAM169A,COG3,DMXL1,CEP350,DNMT3A,RASA1,CLIP4,MBNL2,PCGF3,ELOVL7,FNIP1,FGF9,FOXG1,FOXO1,ARHGEF40,N4BP2,MYT1L,HSPH1,PPARGC1A,ACSL6,GPR161,PAPPA2,DCP2,LMLN" MicroRNA hsa-miR-625:mirSVR_lowEffct hsa-miR-625:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.17E-16 2.22E-12 2.06E-15 1.88E-14 60 1549 "MCC,HOMEZ,ARHGAP5,ATP2B4,B4GALT3,ARHGEF7,CBLN3,CD1E,CDK18,PDE4D,NRXN1,PIK3C2B,LTB4R,POLN,EPN1,PTPRVP,STRN3,COPA,THTPA,DNM3,EPS8L1,COG3,KLHL3,PTPRC,DHFR,NR1I3,ARGLU1,OGFOD2,FAM228A,LRPPRC,EIF2D,EFNA5,MBNL2,MAEA,PCGF3,PCBD2,TOMM40L,N4BP2L2,PIBF1,SELP,FTLP10,FBXO11,G2E3,STPG4,SLC8A1,ZNF605,MYT1L,MCCC2,PPIP5K2,KMT5A,COP1,GPR161,LINC01551,VRK2,NSD2,IGF1,ZNF324B,ZMYM2,LETM1,TTC7A" MicroRNA hsa-miR-3199:mirSVR_lowEffct hsa-miR-3199:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.22E-16 2.25E-12 2.08E-15 1.90E-14 57 1414 "MCC,ADD1,NLN,CUL4A,EP400,MCFD2,PPFIA4,CACNA1E,FCRLB,PCSK1,RGSL1,CHIT1,SMIM14,ATAD2B,C1orf116,POU2F1,VCAN,ZFYVE16,SNX17,PARPBP,DNMT3A,RAN,FAM129A,RNF31,AASDH,FAM228A,RNASEL,KIRREL1,DHRS2,ZNF671,STK32B,N4BP2L2,TMEM175,FBXO11,ZNF446,THADA,POTEM,P2RX2,SLC22A4,MYO16,CMPK2,SRP54,TBC1D1,CNTN2,GPR18,STON1,TGFBI,LINC01551,ADAMTS19,GUF1,VRK2,ZNF470,IL6ST,KIF3C,KIR2DL4,KIT,LINC01913" MicroRNA hsa-miR-1263:mirSVR_lowEffct hsa-miR-1263:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.22E-16 2.25E-12 2.08E-15 1.90E-14 45 910 "MCFD2,ARHGAP5,CENPBD1P1,CD1D,PCDH9,ADGRF3,STRN3,FAM169A,KIAA0040,SREK1,TBC1D4,C14orf119,CLIP4,RNF4,MBNL2,CWC27,SAP18,DLEU1,PCGF3,USP44,PEAR1,SUPT20H,NUBPL,STPG4,POTEM,MEGF10,KIF21B,CENPJ,MRPS27,STRN,PSME4,ACSL6,DOCK9,LINC01551,SLAIN1,STARD4,TADA2B,ZNF84,SELENOI,IL6ST,ZMYM2,LHX9,LINC01913,FAM71C,AXDND1" MicroRNA hsa-miR-196b:mirSVR_highEffct hsa-miR-196b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.42E-16 2.35E-12 2.18E-15 1.99E-14 40 722 "BIRC6,SLAMF6,HOMEZ,SNX24,APAF1,ATP1A2,RAB29,CACNA1E,CHD1,AKAP6,POU2F1,CEP350,KLHL3,PTPRC,RNF31,TMEM161B,NTN4,PACRGL,MBNL2,FNIP1,N4BP2L2,RELL1,FOXO1,VEZT,SCYL2,THADA,SLC12A2,GABRA2,PDS5B,HSPH1,UGT2A1,ANO4,ACSL6,TMPO,GUF1,RXFP2,ZNF10,SPTSSA,ANKS1B,AXDND1" MicroRNA hsa-miR-182*:mirSVR_highEffct hsa-miR-182*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.46E-16 2.37E-12 2.19E-15 2.01E-14 35 548 "BIRC6,MSH2,FAM177A1,CFL2,SMIM14,TAPT1,MATR3,SPATA18,WDR1,AASDH,SLC9C2,EFNA5,ELK3,POLK,VEZT,TADA1,SLC12A2,WDCP,SLC22A5,RAPGEF6,ERAP1,IKBIP,PCDH17,DOCK9,TDG,COX18,FCRLA,TEP1,MAEL,HEXB,KCNT2,IL6ST,ZBED3-AS1,LAD1,RMST" MicroRNA hsa-miR-520a-3p:mirSVR_highEffct hsa-miR-520a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.52E-16 2.41E-12 2.22E-15 2.03E-14 53 1241 "MDM4,KIAA1211,B4GALT3,CCNA1,MORN2,CD1E,FCRLB,RFLNA,PCDH9,FAM177A1,RGSL1,CFL2,PGGT1B,JAKMIP1,HECTD1,THAP6,POU2F1,LYSMD3,CRHBP,C12orf65,ITSN2,CEP135,GNPDA2,CLIP4,NTN4,RNASEL,LATS2,MPHOSPH9,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,HSD17B7,VEZT,FBXO11,BRMS1L,ARHGEF40,NR5A2,YPEL5,MYT1L,ZBTB37,PPIP5K2,MTUS2,ADGRL3,KMT5C,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88,LTA4H" MicroRNA hsa-miR-196a:mirSVR_highEffct hsa-miR-196a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.83E-16 2.57E-12 2.37E-15 2.17E-14 42 798 "BIRC6,HOMEZ,SNX24,APAF1,ARHGAP5,ATP1A2,RAB29,CACNA1E,CHD1,AKAP6,POU2F1,PTGS2,CEP350,KLHL3,PTPRC,RNF31,TMEM161B,NTN4,PACRGL,MBNL2,FNIP1,N4BP2L2,RELL1,FOXO1,VEZT,SCYL2,THADA,CYP1B1-AS1,GABRA2,PDS5B,HSPH1,UGT2A1,ANO4,ACSL6,TMPO,HEXB,GUF1,RXFP2,ZNF10,SPTSSA,ANKS1B,AXDND1" MicroRNA hsa-miR-1201:mirSVR_lowEffct hsa-miR-1201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.85E-16 2.58E-12 2.38E-15 2.18E-14 50 1116 "RALGAPA1,ADD1,PITPNM2,APC,MSH2,SLC5A6,LINC02347,ADGRD1,RILPL1,ODC1,PDE4D,CHD1,EPGN,LACC1,NOS1AP,FCRL2,DCAF8,PIGG,DMXL1,GNPDA2,B3GLCT,SETDB2,EIF2D,DHRS2,PIBF1,SUCO,HSD17B7,G2E3,STPG4,IVNS1ABP,SLC12A2,ZNF667,NPAS3,NFASC,ZNF544,TBC1D1,ADGRA3,ACSL6,C5orf56,RNF17,CRB1,RASSF6,RIMBP2,UBE2K,GUF1,KCNT2,KCNJ9,KCNN2,AXDND1,SKA3" MicroRNA hsa-miR-1292:mirSVR_lowEffct hsa-miR-1292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.01E-16 2.66E-12 2.45E-15 2.25E-14 37 618 "NLN,NYNRIN,MCFD2,PPFIA4,ASCL1,NFATC4,NOVA1,CAMK4,CD1D,PDGFRA,WDFY2,EPN1,TAPT1,C12orf65,ITSN2,CEP135,PRKD1,PTPRC,RNF4,DHRS2,TBC1D19,GP6,FCGR3A,PIBF1,SLC34A2,FBXO11,STPG4,ZNF605,MRPS14,MAST4,TCF7,TPO,STARD4,ZMYM2,FAM151B,LCP1,AXDND1" MicroRNA hsa-let-7g:mirSVR_highEffct hsa-let-7g:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.26E-16 2.80E-12 2.58E-15 2.36E-14 42 800 "MDM4,SLAMF6,HOMEZ,WDR19,SLC4A4,SLC5A6,NOVA1,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,SPATA18,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RB1,RGS12,CWC27,PCGF3,CLIP1,FCGR2B,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,ACSL6,CRB1,HEXB,PAPPA2,VRK2,ZNF10,KIF2A,SPRYD7,AXDND1" MicroRNA hsa-miR-378:mirSVR_lowEffct hsa-miR-378:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.33E-16 2.83E-12 2.60E-15 2.38E-14 62 1650 "ADORA1,ANKRD34B,CENPBD1P1,NFATC4,CCNA1,LINC02347,RAB29,NOVA1,MPZL1,SNTG2,ZNF664,PCDH9,DCLK1,WDFY2,MRPL57,CLOCK,SNCAIP,UBXN2A,GNPDA2,DHFR,NR1H4,FAM129A,RNF31,RASA1,RB1,ZNF419,SETDB2,MBNL2,ABCA11P,FCGR3B,TACC3,SUCO,PEAR1,SH3BP2,DDX51,PAICS,ZNF446,STPG4,ARHGEF40,WDCP,NMNAT2,RAPGEF6,UHRF1BP1L,NFASC,MCCC2,IKBIP,GJA3,ANO4,TCF7,TEP1,GRSF1,BAZ1A,RAB2B,KCNT2,ZNF324B,CCDC169,PLB1,LHX9,EP400P1,RNASE11,LETM1,RMST" MicroRNA hsa-miR-8485:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-16 2.86E-12 2.63E-15 2.40E-14 44 877 "ABL2,SMIM15,TMEM132B,CADM3,SYT2,SLC5A8,FAM177A1,PDGFRA,CFL2,ITGBL1,NUP37,PKP1,C1orf116,TOGARAM2,BRI3BP,CEP135,NOS1AP,SREK1,DMXL1,KLHL3,F11R,MTX3,ATG10,KIRREL1,FGF9,FGFR3,FLT1,BRMS1L,SLC12A2,SLC22A4,MYO16,LILRB1,PPARGC1A,STRN,EML4,RASSF6,HMGCR,TECRL,NLRP8,IL6ST,CCDC169,ZMYM2,FAM49A,SPATA13" MicroRNA hsa-miR-520d-3p:TargetScan hsa-miR-520d-3p TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-302e:TargetScan hsa-miR-302e TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-302c-3p.1:TargetScan hsa-miR-302c-3p.1 TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-520c-3p:TargetScan hsa-miR-520c-3p TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-520b:TargetScan hsa-miR-520b TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-373-3p:TargetScan hsa-miR-373-3p TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-520a-3p:TargetScan hsa-miR-520a-3p TargetScan 5.57E-16 2.96E-12 2.70E-15 2.47E-14 40 727 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-302d-3p:TargetScan hsa-miR-302d-3p TargetScan 5.83E-16 3.10E-12 2.82E-15 2.58E-14 40 728 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-302a-3p:TargetScan hsa-miR-302a-3p TargetScan 5.83E-16 3.10E-12 2.82E-15 2.58E-14 40 728 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-520e:TargetScan hsa-miR-520e TargetScan 5.83E-16 3.10E-12 2.82E-15 2.58E-14 40 728 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-372-3p:TargetScan hsa-miR-372-3p TargetScan 5.83E-16 3.10E-12 2.82E-15 2.58E-14 40 728 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-302b-3p:TargetScan hsa-miR-302b-3p TargetScan 5.83E-16 3.10E-12 2.82E-15 2.58E-14 40 728 "ABL2,MAP1B,APBB2,APC,ARHGEF7,FAM177A1,CFL2,CHD1,GPR180,ATAD2B,RCHY1,POU2F1,EPGN,LYSMD3,CLOCK,FAM169A,NOS1AP,REST,CLIP4,NTN4,LATS2,SBNO1,MBNL2,DNAJC27,IRF9,FGF9,POLK,SDC1,FLT1,FBXO11,BRMS1L,CCDC88A,MYT1L,NPAS3,PCDH17,GPR12,GPR161,KLF12,ARHGAP30,GUF1" MicroRNA hsa-miR-892b:mirSVR_highEffct hsa-miR-892b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.50E-16 3.46E-12 3.14E-15 2.87E-14 43 843 "KIAA1211,APC,NOP14,DAOA,FCHO2,CCNB1,FCRLB,ZNF664,CDK17,PGGT1B,NLRC4,NRXN1,PTPRVP,POU2F1,LRRTM2,CEP135,FCRL5,PPP2R3C,NR1I3,DNMT3A,ATG10,IPO4,CRYL1,CLIP1,TMEM156,C1orf112,NAAA,UHRF1BP1L,OXGR1,SRP72,LRCH1,PPARGC1A,INSM2,ADAM17,YIPF7,TGFBI,ZBTB49,HEXB,TPO,HMGCR,STARD4,IRF1,TDRD3" MicroRNA hsa-miR-506-3p:TargetScan hsa-miR-506-3p TargetScan 6.61E-16 3.51E-12 3.18E-15 2.91E-14 46 961 "MAP1B,CUL4A,FBRSL1,APBB2,KCTD12,ARHGEF7,CDKL2,MPZL1,FAM177A1,CDK18,PDE4D,CFL2,CHD1,AKAP6,LYSMD3,CLOCK,NCOR2,PRKD1,DMXL1,CEP350,F11R,MTX3,IPO4,EFNA5,ELK3,FAM172A,DRAM1,ETF1,PLEKHA6,CCDC88A,NR5A2,LIMCH1,GABRB1,KIF21B,NFASC,MCCC2,LPIN1,ATP11A,METAP2,RIMBP2,ATP6V0A2,LHX9,KIF2A,LCP1,LMNB1,LOX" MicroRNA hsa-miR-124-3p.2:TargetScan hsa-miR-124-3p.2 TargetScan 6.61E-16 3.51E-12 3.18E-15 2.91E-14 46 961 "MAP1B,CUL4A,FBRSL1,APBB2,KCTD12,ARHGEF7,CDKL2,MPZL1,FAM177A1,CDK18,PDE4D,CFL2,CHD1,AKAP6,LYSMD3,CLOCK,NCOR2,PRKD1,DMXL1,CEP350,F11R,MTX3,IPO4,EFNA5,ELK3,FAM172A,DRAM1,ETF1,PLEKHA6,CCDC88A,NR5A2,LIMCH1,GABRB1,KIF21B,NFASC,MCCC2,LPIN1,ATP11A,METAP2,RIMBP2,ATP6V0A2,LHX9,KIF2A,LCP1,LMNB1,LOX" MicroRNA hsa-miR-24-2*:mirSVR_lowEffct hsa-miR-24-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.69E-16 3.56E-12 3.22E-15 2.95E-14 41 768 "MDM4,APAF1,APC,BLZF1,ARHGAP5,ARL1,ASTN1,CACNA1E,MPZL1,CAST,THAP6,LYSMD3,SNCAIP,LACC1,DNM3,OCIAD1,TINF2,MEMO1,DHRS2,ABCA11P,TRAPPC13,SULT6B1,PEAR1,PAICS,CCDC88A,ZNF605,C1orf112,LIMCH1,DCAF11,ATP8A2,NFASC,LILRB1,TBC1D1,LILRB4,TEP1,TMPO,ADAMTS19,ARHGAP30,IL6ST,IRF1,PGAM5" MicroRNA hsa-miR-1911:mirSVR_lowEffct hsa-miR-1911:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.69E-16 3.56E-12 3.22E-15 2.95E-14 41 768 "HOMEZ,ARHGAP5,NFKBIA,UHMK1,SLC5A8,PCDH9,CDK17,RGSL1,CHIT1,GPR180,THAP6,STRN3,KIAA0040,DCAF8,MATR3,SNX17,PTGS2,G3BP2,SUPT7L,DNMT3A,RNF4,ARSK,FGF9,PIBF1,POLK,RUBCNL,FBXO11,BRMS1L,ARHGEF40,PKD2L2,PDS5B,ATP8A2,NEDD1,NMU,PPARGC1A,MTUS2,RNF212,COX18,CRB1,SLAIN1,KCNT2" MicroRNA hsa-miR-939:mirSVR_lowEffct hsa-miR-939:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.78E-16 3.61E-12 3.26E-15 2.98E-14 60 1566 "LRRC43,NDRG2,NYNRIN,TBC1D14,ULK1,CUL4A,PPFIA4,ARL1,NOP14,ASTN1,CENPBD1P1,CADM3,NOVA1,DAOA,CACNA1E,NRL,FCGR2C,CD1E,SNTG2,DCLK1,CDK18,AKAP6,NCOR2,VCAN,CEP135,IFT172,KLHL3,PTPRH,G3BP2,ATG10,CLIP4,SETDB2,EFNA5,MARVELD2,STK32B,F10,FTLP10,STAB2,SLC34A2,MEGF10,KIF21B,MCCC2,ZBTB37,STRN,GJB2,MAST4,GPR12,TCF7,RNF212,NCSTN,SLC7A8,ATP6V0A2,UBE2K,ZNF470,GALP,ZMYM2,LHX9,CAB39L,KIF3C,TTC7A" MicroRNA hsa-miR-449a:mirSVR_highEffct hsa-miR-449a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.14E-16 3.80E-12 3.43E-15 3.14E-14 44 884 "SMIM15,MDM4,BIRC6,COG6,BLZF1,NCOA1,NFATC4,ARHGEF7,CDKL2,FCHO2,CDK18,PDGFRA,CHD1,JAKMIP1,HECTD1,AKAP6,STRN3,PREPL,DNM3,NOS1AP,ZFYVE16,COG3,PPP2R3C,SMC6,RNASEL,SUCO,FOXG1,WDCP,CMPK2,ANO4,DOCK9,TGFBI,TNR,GPN1,TUBA3C,WDR36,CCDC169,PLB1,LINC00272,CHPT1,KCNN2,KIR2DS4,KIT,ZNF304" MicroRNA hsa-miR-449b:mirSVR_highEffct hsa-miR-449b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.14E-16 3.80E-12 3.43E-15 3.14E-14 44 884 "SMIM15,MDM4,BIRC6,COG6,BLZF1,NCOA1,NFATC4,ARHGEF7,CDKL2,FCHO2,CDK18,PDGFRA,CHD1,JAKMIP1,HECTD1,AKAP6,STRN3,PREPL,DNM3,NOS1AP,ZFYVE16,COG3,PPP2R3C,SMC6,RNASEL,SUCO,FOXG1,WDCP,CMPK2,ANO4,DOCK9,TGFBI,TNR,GPN1,TUBA3C,WDR36,CCDC169,PLB1,LINC00272,CHPT1,KCNN2,KIR2DS4,KIT,ZNF304" MicroRNA hsa-miR-648:mirSVR_highEffct hsa-miR-648:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.36E-16 3.92E-12 3.53E-15 3.23E-14 34 524 "COG6,STXBP6,PPP1R12B,CAD,RGSL1,CFL2,CHD1,WDFY2,HECTD1,THAP6,COPA,ITSN2,COG3,CEP350,RABGAP1L,RASA1,AASDH,ZNF419,STK32B,ADGRV1,ELOVL7,TRAPPC13,TOMM40L,SUCO,SELP,LPIN1,PPIP5K2,ANO4,NT5C1B,TMPO,NPL,GPN1,TXK,HSD17B4" MicroRNA hsa-miR-422a:mirSVR_highEffct hsa-miR-422a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.42E-16 3.95E-12 3.55E-15 3.25E-14 42 808 "HOMEZ,BCL2L2,DAOA,NRL,CHAMP1,SLC5A8,CHIT1,ZNF595,GPR180,TM9SF2,PIK3C2B,TOGARAM2,LACC1,DCAF8,TINF2,GNPDA2,IPO4,RGS4,CLIP4,POLR1D,FCGR3A,FOXG1,MROH9,FLT1,MBIP,IVNS1ABP,PKD2L2,GABRB1,ERAP1,MRPS27,STRN,GZMB,UBE2K,GPN1,ZNF876P,VRK2,IL6ST,KIF2A,SLAMF9,LINC01913,NUAK2,SPRYD7" MicroRNA hsa-miR-142-3p.2:TargetScan hsa-miR-142-3p.2 TargetScan 7.43E-16 3.95E-12 3.56E-15 3.26E-14 31 429 "ABL2,CUL4A,APBB2,APC,ARHGAP5,KCTD12,NOVA1,CACNA1E,GAS2L3,FCHO2,DCLK1,FAM177A1,CFL2,POU2F1,HEATR5A,CLOCK,CSNK1G3,RABGAP1L,DRAM1,FBXO11,CCDC88A,NR5A2,KDM5B,FAM114A1,NFASC,PCDH17,PPARGC1A,BAZ1A,ANKS1B,IRF1,KCNN2" MicroRNA hsa-miR-186:PITA hsa-miR-186:PITA_TOP PITA 7.75E-16 4.12E-12 3.70E-15 3.39E-14 42 809 "SMIM15,ADD1,RGS5,MCFD2,ARHGAP5,ARL1,BTF3,CAST,PDE4D,PGGT1B,ATAD2B,CEP135,DNM3,ZFYVE16,COG3,G3BP2,EIF2D,LATS2,MBNL2,ELF1,FNIP1,RELL1,RASA3,VEZT,G2E3,NBEA,SLC12A2,NR5A2,MYT1L,PDS5B,NPAS3,PSME4,TMED2,ACSL6,EML4,KMT5A,COP1,BAZ1A,KLF12,ZMYM2,ZBTB41,SPRYD7" MicroRNA hsa-miR-23b-3p:TargetScan hsa-miR-23b-3p TargetScan 7.95E-16 4.23E-12 3.79E-15 3.47E-14 45 926 "ABL2,MAP1B,MCFD2,APAF1,NCOA1,CADM3,GAS2L3,LDB2,PCK2,CDK17,CFL2,NRXN1,EPN1,RCHY1,POU2F1,HEATR5A,CSNK1G3,DNM3,COG3,DMXL1,CEP350,G3BP2,RNF219,DNMT3A,EFNA5,SBNO1,ELK3,MPHOSPH9,BORA,FNIP1,FBXO11,GABRB1,HSPH1,LRCH1,PCDH17,PPARGC1A,ANO4,EML4,IGSF8,HSP90B1,HTR2A,DCP2,IRF1,NUAK2,LMNB1" MicroRNA hsa-miR-23c:TargetScan hsa-miR-23c TargetScan 7.95E-16 4.23E-12 3.79E-15 3.47E-14 45 926 "ABL2,MAP1B,MCFD2,APAF1,NCOA1,CADM3,GAS2L3,LDB2,PCK2,CDK17,CFL2,NRXN1,EPN1,RCHY1,POU2F1,HEATR5A,CSNK1G3,DNM3,COG3,DMXL1,CEP350,G3BP2,RNF219,DNMT3A,EFNA5,SBNO1,ELK3,MPHOSPH9,BORA,FNIP1,FBXO11,GABRB1,HSPH1,LRCH1,PCDH17,PPARGC1A,ANO4,EML4,IGSF8,HSP90B1,HTR2A,DCP2,IRF1,NUAK2,LMNB1" MicroRNA hsa-miR-23a-3p:TargetScan hsa-miR-23a-3p TargetScan 7.95E-16 4.23E-12 3.79E-15 3.47E-14 45 926 "ABL2,MAP1B,MCFD2,APAF1,NCOA1,CADM3,GAS2L3,LDB2,PCK2,CDK17,CFL2,NRXN1,EPN1,RCHY1,POU2F1,HEATR5A,CSNK1G3,DNM3,COG3,DMXL1,CEP350,G3BP2,RNF219,DNMT3A,EFNA5,SBNO1,ELK3,MPHOSPH9,BORA,FNIP1,FBXO11,GABRB1,HSPH1,LRCH1,PCDH17,PPARGC1A,ANO4,EML4,IGSF8,HSP90B1,HTR2A,DCP2,IRF1,NUAK2,LMNB1" MicroRNA hsa-miR-34c-3p:PITA hsa-miR-34c-3p:PITA_TOP PITA 8.02E-16 4.26E-12 3.82E-15 3.50E-14 24 237 "CAMK4,FCHO2,ZNF664,CDK17,PDE4D,CFL2,PIK3C2B,HOMER1,AKAP6,STRN3,DHX9,MBNL2,SUCO,PEAR1,FOXO1,FLT3,IVNS1ABP,SLC8A1,CCDC88A,MYT1L,KDM5B,PCDH17,PSME4,KIF2A" MicroRNA hsa-let-7d:mirSVR_highEffct hsa-let-7d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.33E-16 4.43E-12 3.96E-15 3.63E-14 41 773 "MDM4,SLAMF6,HOMEZ,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RB1,RGS12,CWC27,PCGF3,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,LRCH1,MAST4,ACSL6,CRB1,HEXB,PAPPA2,VRK2,ZNF10,KIF2A,SPRYD7,AXDND1" MicroRNA hsa-miR-1279:mirSVR_highEffct hsa-miR-1279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.39E-16 4.46E-12 3.99E-15 3.65E-14 44 888 "NLN,COG6,BLZF1,WDR19,ARHGAP5,ZNF542P,ATP4B,BTF3,LDB2,PCDH9,PDGFRA,SMIM14,TAPT1,CLOCK,PTGS2,DMXL1,PTPRC,OCIAD1,SACS,GNPDA2,RGS12,ZNF419,MBNL2,UGT2A3,ELK3,CWC27,SULT6B1,SUCO,ALKAL2,FSHR,MEGF10,FAM114A1,UGT2A1,SCFD1,ADGRL3,ANO4,DOCK9,PAPPA2,KCNT2,JCHAIN,CHPT1,KIT,SPRYD7,LIG4" MicroRNA hsa-miR-20a-5p:TargetScan hsa-miR-20a-5p TargetScan 8.63E-16 4.59E-12 4.09E-15 3.75E-14 46 968 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-93-5p:TargetScan hsa-miR-93-5p TargetScan 8.63E-16 4.59E-12 4.09E-15 3.75E-14 46 968 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-20b-5p:TargetScan hsa-miR-20b-5p TargetScan 8.63E-16 4.59E-12 4.09E-15 3.75E-14 46 968 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-1185:mirSVR_lowEffct hsa-miR-1185:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.77E-16 4.66E-12 4.15E-15 3.80E-14 50 1133 "NYNRIN,WDR35,CUL4A,CENPBD1P1,NOVA1,CAST,RILPL1,CD1D,PCDH9,DCLK1,CFL2,ITGBL1,HECTD1,COPA,RCHY1,LRRTM2,CEP350,PPP2R3C,MEMO1,POLR1D,ELF1,ELK3,MPHOSPH9,CWC27,ELOVL7,IRF9,FCAR,FNIP1,POLK,SUCO,ZCCHC8,CCDC92,SLC30A6,POTEM,NR5A2,EFR3B,CD244,RBKS,BRD8,CNTN2,GTF2H3,BAZ1A,ATP6V0A2,NPL,HSD17B4,WDR36,STARD4,FAM49A,IFT88,ZNF304" MicroRNA hsa-miR-106a-5p:TargetScan hsa-miR-106a-5p TargetScan 8.97E-16 4.77E-12 4.23E-15 3.87E-14 46 969 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-17-5p:TargetScan hsa-miR-17-5p TargetScan 8.97E-16 4.77E-12 4.23E-15 3.87E-14 46 969 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-106b-5p:TargetScan hsa-miR-106b-5p TargetScan 8.97E-16 4.77E-12 4.23E-15 3.87E-14 46 969 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-3174:mirSVR_highEffct hsa-miR-3174:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.97E-16 4.77E-12 4.23E-15 3.87E-14 46 969 "ADD1,COG6,CUL4A,APC,ARL1,STXBP6,FCGR2C,CDK17,RCBTB2,GPR180,GNPTAB,LYSMD3,DNM3,UBXN2A,TINF2,SACS,RABGAP1L,PARPBP,ZNF419,RNASEL,DHRS2,DRAM1,F7,FGF9,SUCO,FOXO1,HSD17B7,NBEA,PAICS,SLC15A4,CYP1B1-AS1,SNRPF,ERBIN,NPFFR2,PPIP5K2,ADGRA3,FCRLA,TMPO,MAEL,HSD17B4,NSD2,C12orf73,ANKS1B,PGAM5,SPRYD7,LOX" MicroRNA hsa-miR-1293:mirSVR_highEffct hsa-miR-1293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.21E-16 4.90E-12 4.34E-15 3.98E-14 34 528 "MDM4,CENPBD1P1,CD1E,UGT2B28,C1orf116,POU2F1,EIF2AK2,SPATA18,SREK1,PTPRC,TINF2,RNF31,DTD2,RNF4,MBNL2,ABCA11P,SELP,SLC30A6,GABRB1,CIDEB,NAAA,TMEM183A,MCCC2,ZBTB37,TCF7,FCRLA,MAEL,UGT2B7,PAPPA2,CCDC169,PLB1,SPRYD7,IFT88,PABPN1" MicroRNA hsa-miR-519d-3p:TargetScan hsa-miR-519d-3p TargetScan 9.67E-16 5.14E-12 4.56E-15 4.17E-14 46 971 "ABL2,MCC,APBB2,ARL1,ATP1A2,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,EPGN,LYSMD3,CLOCK,DCAF8,DGKQ,FBXL5,CEP120,SACS,EGLN3,FAM129A,RB1,REST,RGS4,CLIP4,NTN4,RNF4,ELK3,DNAJC27,IRF9,FLT1,NBEA,BRMS1L,ACIN1,MYT1L,NPAS3,LRCH1,KLHL20,ATP11A,ARHGEF28,KLF12,HTR2A,IL25,IL6ST,IRF1,LHX9" MicroRNA hsa-miR-513a-3p:PITA hsa-miR-513a-3p:PITA_TOP PITA 1.04E-15 5.51E-12 4.88E-15 4.47E-14 41 778 "ARHGAP5,NCOA1,BTF3,NOVA1,FCHO2,CHAMP1,PCCA,PCSK1,CDK17,PDE4D,CFL2,GPR180,NRXN1,SMIM14,HOMER1,MATR3,MTX3,PARPBP,TMEM161B,ELF1,ETF1,FOXO1,NBEA,PLEKHA6,N4BP2,NR5A2,CHFR,JPH4,HSPH1,ERBIN,PCDH17,PPARGC1A,EML4,ZBTB49,ZNF721,HSP90B1,UBE2K,SLAIN1,FIP1L1,LMNB1,LOX" MicroRNA hsa-miR-301a:PITA hsa-miR-301a:PITA_TOP PITA 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "MAP1B,BIRC6,PITPNM2,NCOA1,STARD13,CEBPE,PDGFRA,CFL2,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,CEP120,G3BP2,EGLN3,RASA1,MEMO1,ELK3,MPHOSPH9,CLIP1,NBEA,CCDC88A,MYT1L,ERBIN,KLHL20,PPARGC1A,ATP11A,RIMBP2,ADAMTS19,UBC,SLAIN1,TENT2,DCP2,IGF1,IRF1,KIT" MicroRNA hsa-miR-301b:PITA hsa-miR-301b:PITA_TOP PITA 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "MAP1B,BIRC6,PITPNM2,NCOA1,STARD13,CEBPE,PDGFRA,CFL2,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,CEP120,G3BP2,EGLN3,RASA1,MEMO1,ELK3,MPHOSPH9,CLIP1,NBEA,CCDC88A,MYT1L,ERBIN,KLHL20,PPARGC1A,ATP11A,RIMBP2,ADAMTS19,UBC,SLAIN1,TENT2,DCP2,IGF1,IRF1,KIT" MicroRNA hsa-miR-130a:PITA hsa-miR-130a:PITA_TOP PITA 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "MAP1B,BIRC6,PITPNM2,NCOA1,STARD13,CEBPE,PDGFRA,CFL2,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,CEP120,G3BP2,EGLN3,RASA1,MEMO1,ELK3,MPHOSPH9,CLIP1,NBEA,CCDC88A,MYT1L,ERBIN,KLHL20,PPARGC1A,ATP11A,RIMBP2,ADAMTS19,UBC,SLAIN1,TENT2,DCP2,IGF1,IRF1,KIT" MicroRNA hsa-miR-130b:PITA hsa-miR-130b:PITA_TOP PITA 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "MAP1B,BIRC6,PITPNM2,NCOA1,STARD13,CEBPE,PDGFRA,CFL2,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,CEP120,G3BP2,EGLN3,RASA1,MEMO1,ELK3,MPHOSPH9,CLIP1,NBEA,CCDC88A,MYT1L,ERBIN,KLHL20,PPARGC1A,ATP11A,RIMBP2,ADAMTS19,UBC,SLAIN1,TENT2,DCP2,IGF1,IRF1,KIT" MicroRNA hsa-miR-454:PITA hsa-miR-454:PITA_TOP PITA 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "MAP1B,BIRC6,PITPNM2,NCOA1,STARD13,CEBPE,PDGFRA,CFL2,HOMER1,LYSMD3,CLOCK,LRRTM2,DCAF8,CEP120,G3BP2,EGLN3,RASA1,MEMO1,ELK3,MPHOSPH9,CLIP1,NBEA,CCDC88A,MYT1L,ERBIN,KLHL20,PPARGC1A,ATP11A,RIMBP2,ADAMTS19,UBC,SLAIN1,TENT2,DCP2,IGF1,IRF1,KIT" MicroRNA hsa-miR-3126-3p:mirSVR_highEffct hsa-miR-3126-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-15 5.66E-12 4.98E-15 4.56E-14 37 633 "FAM193A,STARD13,ARHGEF7,CACNA1E,UHMK1,PDGFRA,TAPT1,FAM169A,DMXL1,PARPBP,EGLN3,RASA1,RB1,LAP3,TXNDC15,GORAB,FGF9,FOXG1,MROH9,RUBCNL,NBEA,ARHGEF40,SLC12A2,GABRA2,NAAA,NCSTN,ATP6V0A2,HEXB,ADAMTS19,GUF1,LHX9,FAM151B,ANKDD1B,KIF2A,KIR3DL2,EP400P1,MICU2" MicroRNA hsa-miR-4293:mirSVR_lowEffct hsa-miR-4293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-15 6.05E-12 5.32E-15 4.87E-14 52 1226 "RALGAPA1,IL17D,ADD1,SLAMF6,SNX24,MCFD2,FAM193A,AACS,NFATC4,ARHGEF7,SLC5A6,LINC02347,CAD,CAST,NFXL1,ZNF595,TAPT1,GNPTAB,EPGN,NGDN,SNCAIP,FAM169A,CMTM5,FCRL2,PIGG,FBXL5,RABGAP1L,RABGGTA,FAM129A,SETDB2,DHRS2,ADGRV1,PIBF1,FLT1,FLT3,RASA3,SLC12A2,ZNF667,UGGT2,CYP1B1-AS1,PDS5B,NPAS3,TBC1D1,CNTN2,LILRB4,NCSTN,GRSF1,GPR161,ADAMTS19,GUF1,WDR36,SPRYD7" MicroRNA hsa-miR-3188:mirSVR_highEffct hsa-miR-3188:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-15 6.41E-12 5.63E-15 5.16E-14 43 858 "EP400,ARHGEF7,CDKL2,LDB2,FCRLB,PDGFRA,LINC01085,JAKMIP1,HECTD1,SNCAIP,FCRL5,DCAF8,DCT,COCH,ATG10,POLR1D,STX2,ABCA11P,PCGF3,CLIP1,UTP15,GORAB,PIBF1,STAB2,TM9SF1,MBIP,PAICS,GAK,MRPS27,RBKS,ERBIN,NPFFR2,GJB2,BRD8,TMED2,TDG,NPL,UBE2K,CCDC169,KIR2DL4,TTC41P,LCP1,LMNB1" MicroRNA hsa-miR-3116:mirSVR_highEffct hsa-miR-3116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-15 6.63E-12 5.82E-15 5.33E-14 39 708 "NLN,CUL4A,APC,MSH2,ARHGAP5,KCTD12,NRL,RGSL1,CHD1,PFKFB2,CHIT1,PM20D1,LACC1,VCAN,FAM169A,DNM3,PSME1,PIGG,TINF2,SLC35F6,PARPBP,ATG10,RGS4,SAP18,CLIP1,GORAB,N4BP2L2,UFM1,STPG4,GABRA2,HSPH1,MCCC2,ZBTB37,ADGRA3,KMT5A,HEXB,STARD4,ZMYM2,LOX" MicroRNA hsa-miR-221*:mirSVR_highEffct hsa-miR-221*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-15 6.69E-12 5.87E-15 5.38E-14 38 672 "ABL2,EP400,CDKL4,PNP,CACNA1E,NFXL1,PCK2,VIT,THAP6,HOMER1,HEATR5A,SNCAIP,CSNK1G3,COCH,C14orf119,TSEN15,DNMT3A,RGS4,CLIP4,MPHOSPH9,BORA,TBC1D19,TOMM40L,TM9SF1,NR5A2,ERAP1,KLHL20,PCDH17,SULT1E1,GJA3,KMT5A,TEP1,TGM1,ADAMTS19,HMGCR,GUF1,ANKS1B,TTC41P" MicroRNA hsa-miR-342-3p:mirSVR_highEffct hsa-miR-342-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.30E-15 6.94E-12 6.08E-15 5.57E-14 39 709 "NLN,ATP6V1G3,ASTN1,CDKL2,CAST,PCCA,PDGFRA,PDE6B,LACC1,MATR3,DHX9,PTPRC,OCIAD1,ATG10,RASA1,ZNF329,NTN4,LATS2,DRAM1,F10,PIBF1,FOXG1,NBEA,PLEKHA6,NUBPL,TADA1,NPAS3,ANKLE2,LPIN1,ADGRA3,DOCK9,TDG,TXK,ZNF876P,HTR2A,ZBED3-AS1,TMEM178A,KIF2A,AXDND1" MicroRNA hsa-miR-362-3p:Functional MTI Functional MTI miRTarbase 1.43E-15 7.63E-12 6.68E-15 6.12E-14 34 536 "SMIM15,ATP6V1G3,SYT2,FAM177A1,WDR66,CFL2,ITGBL1,NUP37,C1orf116,BRI3BP,CEP135,NOS1AP,DMXL1,KLHL3,MTX3,ATG10,REST,KIRREL1,FGF9,BRMS1L,SLC12A2,SLC22A4,LILRB1,PPARGC1A,EML4,RASSF6,HMGCR,TECRL,NLRP8,DCP2,IL6ST,CCDC169,ZMYM2,SPATA13" MicroRNA hsa-miR-196b:mirSVR_lowEffct hsa-miR-196b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-15 8.37E-12 7.32E-15 6.70E-14 52 1236 "NYNRIN,EP400,ASCL1,NFKBIA,NOVA1,PNP,CAST,FCHO2,MORN2,RGSL1,PDGFRA,ITGBL1,PIK3C2B,FAM169A,DNM3,UBXN2A,ZNF586,ZFYVE16,PIGG,PARPBP,B3GLCT,RASA1,ZNF329,AASDH,MEMO1,GUSBP3,CLIP1,SUCO,ZNF605,EFR3B,MYO16,CMPK2,MCCC2,MIMT1,CFHR4,GJB2,MAST4,TCF7,DOCK9,RNF212,CRB1,GZMH,MAEL,NPL,NSD2,KCNT2,ZNF84,PLB1,LMLN,LINC00442,RMST,PABPN1" MicroRNA hsa-miR-329-3p:Functional MTI Functional MTI miRTarbase 1.60E-15 8.51E-12 7.44E-15 6.81E-14 34 538 "SMIM15,ATP6V1G3,SYT2,FAM177A1,WDR66,CFL2,ITGBL1,NUP37,C1orf116,BRI3BP,CEP135,NOS1AP,DMXL1,KLHL3,MTX3,ATG10,REST,KIRREL1,FGF9,BRMS1L,SLC12A2,SLC22A4,LILRB1,PPARGC1A,EML4,RASSF6,HMGCR,TECRL,NLRP8,DCP2,IL6ST,CCDC169,ZMYM2,SPATA13" MicroRNA hsa-miR-1193:mirSVR_lowEffct hsa-miR-1193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-15 8.93E-12 7.80E-15 7.14E-14 52 1238 "ADD1,SLAMF6,HOMEZ,APC,DAOA,CAST,PCDH9,LINC01085,POU2F1,CLOCK,CRHBP,SNCAIP,CEP135,UBXN2A,FCRL2,DCAF8,IFT172,MATR3,PSMA6,DMXL1,OCIAD1,F11R,PTPRH,RASA1,DTD2,DRAM1,ARSK,ADGRV1,PCGF3,PCBD2,TOMM40L,POLK,SCYL2,SLC15A4,SLC22A4,YPEL5,MEGF10,PDS5B,SRP54,NFASC,ZBTB37,TCF7,C1QTNF9B,AP4S1,ADAMTS19,RXFP2,PAPPA2,ZNF84,KIR2DL1,TTC41P,RMST,AXDND1" MicroRNA hsa-miR-193a-5p:mirSVR_lowEffct hsa-miR-193a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.73E-15 9.22E-12 8.04E-15 7.37E-14 52 1239 "NOP14,FAM193A,LINC02347,CAST,PCCA,CDK18,PFKFB2,ITGBL1,TM9SF2,NRXN1,THAP6,C12orf65,UBXN2A,GLT8D2,SNX17,COG3,TSEN15,REST,DTD2,SLC9C2,RGS4,LRPPRC,FAM81B,TNFRSF19,SELP,GOLGA2P5,ZNF446,IVNS1ABP,POTEM,CYP1B1-AS1,GABRA2,NMNAT2,KDM3B,MTUS2,STON1,XPO4,CRB1,GPR161,ZBTB49,LINC01551,RASSF6,KLF12,HSP90B1,GPN1,TECRL,NSD2,ZNF470,SPTSSA,TMEM178A,KIR2DL4,TTC41P,LINC01913" MicroRNA hsa-miR-196b*:mirSVR_lowEffct hsa-miR-196b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-15 9.49E-12 8.27E-15 7.57E-14 34 540 "LRRC43,HOMEZ,FAM193A,AACS,NEDD8,FCRL3,ADGRD1,PAH,RFLNA,C1orf116,AKAP6,STRN3,EPS8L1,SREK1,RABGAP1L,DNMT3A,AASDH,DTD2,CRYL1,LATS2,C1orf112,YPEL5,MYO16,GABRA2,NPAS3,KMT5A,DOCK9,FCRLA,CRB1,AP4S1,YTHDC2,ZMYM2,KIF3C,LINC00442" MicroRNA hsa-miR-654-3p:mirSVR_highEffct hsa-miR-654-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.00E-15 1.06E-11 9.27E-15 8.48E-14 44 910 "KIAA1211,CAST,CD1D,PCK2,CDK17,RGSL1,CKMT2,CFAP54,NRXN1,JAKMIP1,UBXN2A,PARPBP,B3GLCT,NTN4,GRTP1,ZNF256,MARVELD2,ETF1,ABCA11P,FLT1,C1orf112,GABRB1,CD244,OXGR1,SRP72,RBKS,COMMD6,PPARGC1A,UGT2A1,GOLGA3,ADGRL3,RNF17,TMPO,HEXB,TECRL,GUF1,TENT2,VRK2,ZMYM2,LHX9,FIP1L1,RMST,AXDND1,MICU2" MicroRNA hsa-miR-214*:mirSVR_lowEffct hsa-miR-214*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-15 1.12E-11 9.74E-15 8.92E-14 54 1333 "NLN,WDR35,HOMEZ,ASTN1,NOVA1,CBLN3,XPR1,GLT1D1,THAP6,HOMER1,TAPT1,COPA,GNPTAB,SNCAIP,LRRTM2,UBXN2A,ZFYVE16,COG3,GNPDA2,PARPBP,NR1H4,EGLN3,B3GLCT,FAM228A,DTD2,RGS12,GUSBP3,TXNDC15,GRTP1,MBNL2,BORA,SAP18,TOMM40L,N4BP2L2,PAICS,IVNS1ABP,UGGT2,DCAF11,CMPK2,NFASC,ZBTB37,GJB2,ADGRL3,ANO4,DOCK9,KHNYN,MAEL,TPO,TECRL,YTHDC2,MZF1,ZFHX2,CAB39L,KIF3C" MicroRNA hsa-miR-490-5p:mirSVR_highEffct hsa-miR-490-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.15E-15 1.14E-11 9.94E-15 9.10E-14 39 720 "ATP6V1G3,ARHGEF7,CACNA1E,DCLK1,PDGFRA,PFKFB2,NRXN1,ADGRF3,THAP6,RCHY1,RNASE9,LACC1,DNM3,MPHOSPH8,FCRL5,SPATA18,COCH,OCIAD1,PARPBP,TSEN15,EGLN3,CLIP4,RNF4,MARVELD2,BORA,ETF1,FLT1,CCDC88A,ERBIN,METAP2,TDG,FCRLA,TFDP1,STARD4,LHX9,CHPT1,DIAPH3,RMST,AXDND1" MicroRNA hsa-miR-200b*:mirSVR_highEffct hsa-miR-200b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.16E-15 1.15E-11 9.98E-15 9.14E-14 45 952 "MAP1B,FAM193A,ASTN1,NOVA1,CAST,UHMK1,THAP6,RCHY1,SYCP3,EIF2AK2,DDX59,ZFYVE16,NUDT12,NR1I3,NR1H4,ATG10,UGT2A3,STX2,FAM172A,DNAJC27,CCDC38,FGFR3,RELL1,UFM1,TADA1,C1orf112,SLC22A4,LIMCH1,GABRA2,PDS5B,NAAA,OXGR1,RBKS,SULT1E1,AURKC,INSM2,C5orf56,TMPO,ATP6V0A2,ADAMTS19,WDR36,NSD2,KCNT2,SDR39U1,LOX" MicroRNA hsa-miR-141-3p:TargetScan hsa-miR-141-3p TargetScan 2.55E-15 1.36E-11 1.18E-14 1.08E-13 37 651 "ABL2,KIAA1211,FBRSL1,APBB2,KCTD12,CACNA1E,CDK17,CFL2,NRXN1,ATAD2B,EPN1,HECTD1,EPGN,LYSMD3,CLOCK,BRI3BP,CSNK1G3,PRKD1,MATR3,DMXL1,G3BP2,MEMO1,ELK3,PCGF3,BRMS1L,MYT1L,PDS5B,ATP8A2,NPAS3,NFASC,ANKLE2,GPR12,MSH6,KLF12,HTR2A,DCP2,LMLN" MicroRNA hsa-miR-200a-3p:TargetScan hsa-miR-200a-3p TargetScan 2.55E-15 1.36E-11 1.18E-14 1.08E-13 37 651 "ABL2,KIAA1211,FBRSL1,APBB2,KCTD12,CACNA1E,CDK17,CFL2,NRXN1,ATAD2B,EPN1,HECTD1,EPGN,LYSMD3,CLOCK,BRI3BP,CSNK1G3,PRKD1,MATR3,DMXL1,G3BP2,MEMO1,ELK3,PCGF3,BRMS1L,MYT1L,PDS5B,ATP8A2,NPAS3,NFASC,ANKLE2,GPR12,MSH6,KLF12,HTR2A,DCP2,LMLN" MicroRNA hsa-miR-365*:mirSVR_lowEffct hsa-miR-365*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-15 1.39E-11 1.20E-14 1.10E-13 45 957 "TMEM132B,ADD1,NFATC4,ARHGEF7,ADGRD1,NRL,SYT2,PAH,DHRS1,WDFY2,SNCAIP,DNM3,FCRL5,SNX17,PIGG,GNPDA2,PARPBP,B3GLCT,GUSBP3,EIF2B1,MARVELD2,ABCA11P,N4BP2L2,SUCO,FOXG1,RASA3,IVNS1ABP,POTEM,SLC22A5,UHRF1BP1L,NFASC,RBKS,C5orf56,TCF7,KHNYN,COX18,TGFBI,BAZ1A,RAB2B,PLB1,LHX9,CHPT1,KCNJ9,LOX,ZNF304" MicroRNA hsa-miR-4270:mirSVR_highEffct hsa-miR-4270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.70E-15 1.44E-11 1.24E-14 1.14E-13 42 839 "KIAA1211,NYNRIN,CADM3,CCNA1,NOVA1,ZMYM5,CDK18,MRPL57,NRXN1,PM20D1,LACC1,PRKD1,DCAF8,NUDT12,EGLN3,B3GLCT,SMC6,RNF4,MARVELD2,CWC27,SAP18,PEAR1,SELP,GOLGA2P5,TADA1,CCDC88A,CGREF1,PDS5B,TMEM183A,CD244,PPARGC1A,UGT2A1,INSM2,NCSTN,TFDP1,GTF2H3,HSP90B1,MZF1,JCHAIN,CCDC169,TTC41P,PABPN1" MicroRNA hsa-miR-29c:mirSVR_highEffct hsa-miR-29c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.75E-15 1.46E-11 1.26E-14 1.16E-13 48 1082 "SFTA3,SNX24,APC,CDKL2,SNTG2,SLC5A8,PDGFRA,CFAP54,ATAD2B,THAP6,DCAF8,IFT172,SREK1,LOC439933,DNMT3A,ARGLU1,POLR1D,RNASEL,EFNA5,FMO1,NUBPL,SLC12A2,CHFR,MYO16,KDM5B,NAAA,TMEM183A,NPAS3,RBKS,MCCC2,LRCH1,PSME4,PPIP5K2,METAP2,ADGRA3,EML4,KMT5C,TDG,FCRLA,ADAMTS19,GPN1,HMGCR,HTR2A,IGF1,RILPL2,NUAK2,IFT88,LOX" MicroRNA hsa-miR-4302:mirSVR_highEffct hsa-miR-4302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-15 1.47E-11 1.27E-14 1.16E-13 40 763 "SNX24,APAF1,SLC4A4,ZNF542P,PPP1R12B,NFATC4,NFKBIA,CAST,PCK2,RGSL1,CHD1,ATAD2B,EPGN,PREPL,UBXN2A,ZNF586,COG3,COCH,CEP120,PTPRC,C14orf119,ETF1,SLC22A17,PAICS,SLC8A1,GABRA2,ZNF274,IQGAP2,ZNF544,METAP2,LINC01551,GPN1,CHPT1,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,TTC41P,LMNB1" MicroRNA hsa-miR-101-3p.2:TargetScan hsa-miR-101-3p.2 TargetScan 2.76E-15 1.47E-11 1.27E-14 1.16E-13 41 801 "PPFIA4,APC,KCTD12,NOVA1,CHAMP1,CDK17,PDE4D,ATAD2B,HOMER1,POU2F1,LRRTM2,COG3,PTGS2,CEP350,G3BP2,MTX3,DNMT3A,RASA1,IPO4,EFNA5,MBNL2,MPHOSPH9,FOXG1,NR5A2,LIMCH1,PDS5B,NPAS3,KDM3B,NFASC,PPARGC1A,ADAM17,ACSL6,GRSF1,KLF12,HSP90B1,HMGCR,PAPPA2,DCP2,LHX9,KIF2A,KIT" MicroRNA hsa-miR-18b:mirSVR_highEffct hsa-miR-18b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.81E-15 1.50E-11 1.29E-14 1.18E-13 39 726 "NCOA1,CAD,PCK2,PCSK1,PDE4D,NRXN1,ADGRF3,COPA,RNASE9,HEATR5A,MATR3,BIVM,COG3,GNPDA2,SUPT7L,PARPBP,SLC9C2,RNASEL,RNF4,FAM172A,EFS,FCGR2B,SUCO,MROH9,C1orf112,KDM5B,NAAA,SRP54,KLHL20,LPIN1,PPARGC1A,PSME4,PPIP5K2,YIPF7,MAEL,NPL,TRPC4,TXK,RMST" MicroRNA hsa-miR-18b*:mirSVR_lowEffct hsa-miR-18b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.94E-15 1.56E-11 1.35E-14 1.23E-13 39 727 "APC,FAM193A,BCL2L2,BTF3,CAST,FCRLB,CDK7,ATAD2B,THAP6,IFT172,CEP120,B3GLCT,DTD2,ETF1,TOMM40L,NDUFAF7,SDC1,BRMS1L,IVNS1ABP,TADA1,ZNF605,ZNF667,GABRB1,NAAA,ERAP1,KLHL20,MAST4,ADAM17,C5orf56,DOCK9,CRB1,MAEL,ADAMTS19,UBE2K,VRK2,TDRD3,KIR2DS4,KIR3DL1,LOX" MicroRNA hsa-miR-4326:mirSVR_highEffct hsa-miR-4326:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.95E-15 1.57E-11 1.35E-14 1.24E-13 37 654 "SMIM15,ACOX3,WDR35,ARL1,CD1E,PDE4D,NRXN1,LRRTM2,ZNF586,DMXL1,REST,RNASEL,TXNDC15,MBNL2,TRAPPC12,ABCA11P,TMEM156,NDUFAF7,LRRN2,POLK,NBEA,MEGF10,PDS5B,TMEM183A,EML4,RNF17,SLC7A8,AP4S1,MAEL,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,LAD1,PABPN1,ZNF304" MicroRNA hsa-miR-3200:mirSVR_highEffct hsa-miR-3200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.04E-15 1.62E-11 1.39E-14 1.27E-13 29 390 "ACOX3,COG6,SNX24,FBRSL1,LDB2,UHMK1,CHD1,AKAP6,EPGN,CSNK1G3,TSEN15,EGLN3,TMEM161B,AASDH,LATS2,ETF1,ABCA11P,PIBF1,FLT1,SLC12A2,MEGF10,ERAP1,LINC02393,CRB1,ADAMTS19,KLF12,ZMYM2,AXDND1,PABPN1" MicroRNA hsa-miR-646:mirSVR_highEffct hsa-miR-646:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-15 1.69E-11 1.45E-14 1.33E-13 42 843 "RALGAPA1,MDM4,CCDC181,BTF3,PNP,LDB2,SNTG2,VIT,PGGT1B,LINC01085,HECTD1,AKAP6,PRKD1,DCAF8,SREK1,COG3,CEP350,TBC1D4,GNPDA2,ATG10,DTD2,LATS2,ELOVL7,GORAB,RUBCNL,G2E3,NBEA,MYT1L,NPAS3,PPARGC1A,BRD8,METAP2,TCF7,RNF212,RNF17,CRB1,HAL,DCP2,ZNF10,KIF2A,TTC41P,NUAK2" MicroRNA hsa-miR-4299:mirSVR_highEffct hsa-miR-4299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.21E-15 1.71E-11 1.47E-14 1.34E-13 39 729 "STXBP6,ZNF542P,CD84,PNP,TAF1B,RGSL1,PDE4D,CHIT1,THAP6,SNCAIP,CSNK1G3,LRRTM2,PARPBP,NR1H4,DTD2,CLIP4,PACRGL,TRIM28,ELK3,ARSK,CLIP1,PIBF1,FLT3,G2E3,NBEA,IVNS1ABP,POTEM,TMEM132D,UHRF1BP1L,PPARGC1A,MAST4,ADGRL3,ANO4,C5orf56,FCRLA,LINC01551,RAB2B,SLAIN1,IFT88" MicroRNA hsa-miR-3135:mirSVR_lowEffct hsa-miR-3135:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.26E-15 1.73E-11 1.49E-14 1.36E-13 45 963 "TMEM132B,FBRSL1,ARL1,ASTN1,CENPBD1P1,MYH6,CD84,MPZL1,SYT2,RILPL1,RFLNA,PDE4D,PFKFB2,CPNE6,PIGR,BOD1L1,THTPA,CMTM5,CEP350,F11R,RGS12,LRPPRC,TXNDC15,LATS2,DRAM1,NDUFAF7,TNFRSF19,FLT1,RUBCNL,IVNS1ABP,TADA1,LIMCH1,NAAA,SULT1E1,LPIN1,PPARGC1A,ACSL6,NCSTN,ADAMTS19,ZNF470,PLB1,SPRYD7,AXDND1,LOX,ZNF304" MicroRNA hsa-let-7e:mirSVR_highEffct hsa-let-7e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.26E-15 1.74E-11 1.49E-14 1.36E-13 41 805 "MDM4,SLAMF6,HOMEZ,BLZF1,WDR19,SLC4A4,SLC5A6,NOVA1,TAF1B,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,CEP120,PTPRC,PARPBP,NR1H4,ATG10,RNF31,RGS12,CWC27,PCGF3,CLIP1,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,LRCH1,MAST4,ACSL6,CRB1,PAPPA2,ZNF10,SPRYD7,AXDND1" MicroRNA hsa-miR-449b*:mirSVR_highEffct hsa-miR-449b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-15 1.76E-11 1.51E-14 1.38E-13 42 844 "ANKRD34B,WDR35,APC,CENPBD1P1,NEDD8,FCRL3,CACNA1E,MPZL1,FCHO2,UHMK1,NFXL1,PCK2,PDGFRA,RCBTB2,SMIM14,BOD1L1,EPGN,PIGG,ARSK,CLIP1,PIBF1,HSD17B7,FMO1,SUPT20H,SLC34A2,ALKAL2,NUBPL,WDCP,MYO16,PDS5B,TMEM183A,NPFFR2,ZNF544,ADGRL3,STON1,EML4,TDG,GTF2H3,FZD10,ADAMTS19,ZMYM2,KIT" MicroRNA hsa-miR-941:mirSVR_lowEffct hsa-miR-941:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.34E-15 1.78E-11 1.52E-14 1.39E-13 36 621 "IL17D,CUL4A,ZNF784,BLZF1,FCRLB,MRPL57,THAP6,TAPT1,POLE,C12orf65,UBXN2A,NOS1AP,ZFYVE16,BIVM,NR1I3,RGS12,GUSBP3,GP6,ABCA11P,TMEM129,FCAR,SH3BP2,THADA,ZNF605,GABRB1,ATP8A2,PPARGC1A,ZNF544,LINC02393,KMT5C,RNF212,ACTR6,ZNF721,ATP6V0A2,TECRL,WDR36" MicroRNA hsa-miR-4300:mirSVR_lowEffct hsa-miR-4300:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-15 1.86E-11 1.59E-14 1.45E-13 52 1261 "LRRC43,ULK1,CUL4A,NOP14,FAM193A,ATP2B4,BCL2L2,LINC02347,NOVA1,NRL,ZNF664,CDK17,PTPRVP,TAPT1,SNCAIP,C12orf65,COG3,SLC35F6,RGS4,LAP3,CLIP4,SETDB2,FAM81B,PCGF3,F7,F10,POLK,SUCO,STPG4,CGREF1,MRPS14,TMEM183A,RBKS,METAP2,GPR12,TCF7,KHNYN,RNF212,TGM1,ARHGAP30,GUF1,ZFHX2,PLB1,NPHS2,ANKDD1B,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,LINC00442,RMST,LTA4H" MicroRNA hsa-miR-4325:mirSVR_highEffct hsa-miR-4325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.56E-15 1.89E-11 1.62E-14 1.48E-13 44 925 "MDM4,KIAA1211,FBRSL1,MSH2,ASCL1,FGFRL1,CAST,FCHO2,CDK17,PDGFRA,SLC25A3,SNX6,HECTD1,STRN3,TAPT1,C12orf65,NOS1AP,SREK1,DMXL1,GNPDA2,NR1H4,RNF4,ABCA11P,TRAPPC13,FNIP1,POLK,SCYL2,ZNF605,CYP1B1-AS1,GABRA2,IQGAP2,LILRB1,PPIP5K2,DOCK9,TFDP1,LINC01551,ZNF721,ADAMTS19,GUF1,VRK2,KCNT2,ZMYM2,ANKDD1B,LOX" MicroRNA hsa-miR-519e:mirSVR_lowEffct hsa-miR-519e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.82E-15 2.03E-11 1.73E-14 1.59E-13 53 1308 "SMIM15,ATP6V1G3,APC,ZNF784,ARL1,RAB29,SCARB1,WDR66,TSTD1,GALNT9,C12orf65,DNM3,ZFYVE16,SPATA18,PSME1,COG3,OCIAD1,GNPDA2,ATG10,OGFOD2,EFS,ETF1,GMPR2,TRAPPC13,FCAR,NDUFAF7,LRRN2,PEAR1,FOXO1,SUPT20H,STPG4,TADA1,GABRA2,PDS5B,NMNAT2,JPH4,ERAP1,LRCH1,GJA3,STON1,TFDP1,CRB1,LINC01551,ARHGAP30,TECRL,SLAIN1,IL25,IL6ST,SDR39U1,ZBED3-AS1,KIT,LINC01913,LMNB1" MicroRNA hsa-miR-1324:mirSVR_highEffct hsa-miR-1324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.97E-15 2.11E-11 1.80E-14 1.65E-13 50 1178 "KIAA1211,APAF1,NFATC4,RILPL1,UHMK1,CDK17,CKMT2,THAP6,HOMER1,EPGN,CEP135,UBXN2A,FCRL2,SPATA18,DMXL1,RABGAP1L,RAN,SMC6,RNASEL,EFNA5,MPHOSPH9,SAP18,ETF1,RELL1,SUCO,FLT3,VEZT,BRMS1L,IVNS1ABP,N4BP2,C1orf112,MRPS14,GABRA2,MYT1L,NPAS3,SRP72,LRCH1,EML4,TDG,CRB1,SLC7A8,ZBTB49,GTF3C2,SLAIN1,NSD2,TADA2B,SPTSSA,ANKS1B,LMNB1,LOX" MicroRNA hsa-miR-4323:mirSVR_lowEffct hsa-miR-4323:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.04E-15 2.15E-11 1.83E-14 1.68E-13 56 1445 "RALGAPA1,MDM4,NDRG2,TMEM132B,ARHGAP5,AACS,BCL2L2,PFKFB2,VIT,ITGBL1,PKP1,ITSN2,CEP135,DCAF8,EPS8L1,PIGG,ARGLU1,TMEM161B,OGFOD2,AASDH,GRTP1,SPATA9,BORA,EFS,STK32B,DNAJC27,PCBD2,LRRN2,RASA3,GOLGA2P5,NUBPL,SLC15A4,SLC22A5,DCAF11,MYO16,GABRB1,MRPS27,NFASC,DRC1,LRCH1,ZNF544,ADGRL3,KMT5C,RNF17,GRSF1,GPR161,MAEL,TPO,ADAMTS19,NLRP8,PAPPA2,ZNF10,PGAM5,CHPT1,LCP1,SKA3" MicroRNA hsa-miR-331-3p:mirSVR_lowEffct hsa-miR-331-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.15E-15 2.21E-11 1.88E-14 1.72E-13 48 1094 "SEMA6A,CUL4A,CENPBD1P1,CADM3,ATP7B,CCNA1,LDB2,PDGFRA,PIGR,THAP6,FAM163A,FCRL5,SNX17,EPS8L1,COG3,RGS12,LGR6,DRAM1,PCGF3,F10,TOMM40L,GORAB,SDC1,SLC8A1,ZNF605,ACIN1,DCAF11,KIF21B,NMNAT2,JPH4,CD244,ATP8A2,NFASC,ERBIN,LILRB1,ZBTB37,MAST4,ADGRL3,LILRB4,C5orf56,RIPK3,AP4S1,NPL,RXFP2,HSD17B4,NSD2,JCHAIN,LHX9" MicroRNA hsa-miR-455-3p:mirSVR_highEffct hsa-miR-455-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.30E-15 2.29E-11 1.95E-14 1.78E-13 43 890 "NLN,CENPBD1P1,BTF3,NOVA1,CDKL2,PCCA,PDGFRA,SLC25A3,GPR180,LINC01085,ATAD2B,PITX1,JAKMIP1,HECTD1,HOMER1,COPA,NGDN,CSNK1G3,FCRL5,ZFYVE16,IFT172,NTN4,SETDB2,TRAPPC12,DLEU1,N4BP2L2,TNFRSF19,SLC12A2,SLC22A4,ZNF667,GABRA2,SRP72,MAST4,TBC1D1,ACSL6,FZD10,DCP2,LINC00272,FAM151B,ZBED3-AS1,RILPL2,IFT88,LOX" MicroRNA hsa-miR-553:mirSVR_lowEffct hsa-miR-553:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.93E-15 2.62E-11 2.23E-14 2.04E-13 36 629 "RALGAPA1,TBC1D14,WDR35,ARHGAP5,ATP2B4,ARHGEF7,SLC5A6,PNP,CD1D,XPR1,CHD1,NUP37,ATAD2B,C1orf116,STRN3,POLE,SNCAIP,EIF2AK2,BIVM,WDR1,PACRGL,MBNL2,DCUN1D2,MPHOSPH9,N4BP2L2,FLT1,BRMS1L,TMEM132D,LRCH1,MIMT1,FCRL6,TADA2B,SELENOI,CCDC190,ANKS1B,LMLN" MicroRNA hsa-miR-1302:mirSVR_highEffct hsa-miR-1302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.02E-15 2.67E-11 2.27E-14 2.08E-13 40 777 "RALGAPA1,ARHGEF7,NOVA1,CD1E,PCDH9,PCK2,FAM177A1,RGSL1,GLT1D1,GNPTAB,PM20D1,PRKD1,FCRL5,ZNF586,SNX17,OCIAD1,EGLN3,CLIP4,ABCA11P,FCGR3A,FCGR3B,POLK,SUCO,FBXO11,THADA,ZNF667,YPEL5,MEGF10,PDS5B,IQGAP2,NEDD1,IKBIP,ZBTB37,ACSL6,FCRLA,MAEL,ZNF26,MZF1,NPHS2,LIG4" MicroRNA hsa-miR-570:PITA hsa-miR-570:PITA_TOP PITA 5.05E-15 2.69E-11 2.28E-14 2.09E-13 46 1016 "ABL2,MAP1B,NLN,SEMA6A,MYBPC1,KCTD12,NFXL1,DCLK1,CFL2,CHD1,NRXN1,SMIM14,SNX6,ATAD2B,AKAP6,CEP135,DNM3,BIVM,SREK1,DMXL1,COCH,CLIP4,EFNA5,MBNL2,ELF1,FAM172A,ETF1,FOXO1,FLT3,ZCCHC8,SLC8A1,NR5A2,MYT1L,PDS5B,FAM114A1,KDM3B,NEDD1,NMU,STRN,TMED2,RIMBP2,TENT2,ZBTB41,NUAK2,SPRYD7,CDK2AP1" MicroRNA hsa-miR-29a:mirSVR_highEffct hsa-miR-29a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.05E-15 2.69E-11 2.28E-14 2.09E-13 46 1016 "SFTA3,SNX24,APC,CDKL2,MPZL1,SNTG2,SLC5A8,PDGFRA,CFAP54,ATAD2B,THAP6,LYSMD3,DCAF8,IFT172,SREK1,LOC439933,DNMT3A,ARGLU1,POLR1D,RNASEL,EFNA5,FMO1,NUBPL,CHFR,MYO16,KDM5B,TMEM183A,NPAS3,RBKS,MCCC2,LRCH1,PPIP5K2,METAP2,ADGRA3,EML4,KMT5C,TDG,FCRLA,ADAMTS19,GPN1,HMGCR,IGF1,RILPL2,NUAK2,IFT88,LOX" MicroRNA hsa-miR-7:mirSVR_highEffct hsa-miR-7:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.12E-15 2.72E-11 2.31E-14 2.11E-13 47 1058 "KIAA1211,SEMA6A,ARHGAP5,NCOA1,ASTN1,ZNF542P,ATP7B,FCHO2,CHAMP1,CDK17,PDE4D,SNX6,THAP6,STRN3,CMTM5,TSEN15,DNMT3A,GALNT14,EGLN3,B3GLCT,RB1,CWC27,MAEA,ELOVL7,FCGR3A,TOMM40L,GORAB,PIBF1,TADA1,MYO16,GABRA2,KDM5B,NAAA,GJB6,KDM3B,PSME4,ANO4,NT5C1B,BAZ1A,RAB2B,TPTE2,KCNT2,ZMYM2,ZAR1L,TTC41P,AXDND1,LMNB1" MicroRNA hsa-miR-380*:mirSVR_lowEffct hsa-miR-380*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-15 2.73E-11 2.31E-14 2.12E-13 42 855 "RALGAPA1,MCC,SLC4A4,NOVA1,CHAMP1,SLC5A8,PCDH9,RGSL1,PDGFRA,CENPC,ADGRF3,LTB4R,AKAP6,VCAN,MATR3,COCH,PTPRC,OCIAD1,DHFR,LINC01257,PARPBP,RGS4,RNF4,ADGRV1,N4BP2L2,TNFRSF19,SUPT20H,GOLGA2P5,PLEKHA6,ZNF274,ATP8A2,NFASC,UGT2A1,ADGRA3,TFDP1,CRB1,ZNF140,ZMYM2,CHPT1,KCNN2,KIF3C,LAD1" MicroRNA hsa-miR-1915*:mirSVR_highEffct hsa-miR-1915*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.31E-15 2.83E-11 2.39E-14 2.19E-13 31 461 "KIAA1211,MSH2,ATP7B,PNP,SCFD2,ZNF595,PKP1,HECTD1,ZFYVE16,TBC1D4,RASA1,AASDH,RNASEL,ARL6IP4,FCAR,NDUFAF7,HSD17B7,SLC15A4,ACIN1,NAAA,NFASC,ADGRL3,C5orf56,TCF7,IGF1,CCDC169,SDR39U1,KCNJ9,KCNN2,AXDND1,IFT88" MicroRNA hsa-miR-369-3p:TargetScan hsa-miR-369-3p TargetScan 5.31E-15 2.83E-11 2.39E-14 2.19E-13 31 461 "MCFD2,APBB2,ARHGAP5,DCLK1,PDE4D,CFL2,NUP37,HECTD1,HOMER1,LYSMD3,COG3,DMXL1,CEP350,KLHL3,OCIAD1,RABGAP1L,CLIP4,EFNA5,MBNL2,PCGF3,ELOVL7,FNIP1,FOXG1,FOXO1,FLT1,G2E3,SCYL2,ARHGEF40,HSPH1,PAPPA2,DCP2" MicroRNA hsa-miR-1178:mirSVR_highEffct hsa-miR-1178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.50E-15 2.93E-11 2.47E-14 2.26E-13 38 704 "STARD13,DAOA,CBLN3,PCCA,WDR66,PIWIL1,ATAD2B,LTB4R,NOS1AP,ZFYVE16,SREK1,DMXL1,G3BP2,SUPT7L,SLC35F6,NR1H4,RGS12,LATS2,ARSK,MAEA,DLEU1,PLEKHA6,P2RX2,GABRA2,GABRB1,TMEM183A,IQGAP2,PPIP5K2,TCF7,STON1,KHNYN,LINC01551,TMPO,RIMBP2,UGT2B7,WDR36,ZNF26,ZBTB41" MicroRNA hsa-miR-3142:mirSVR_highEffct hsa-miR-3142:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.69E-15 3.03E-11 2.55E-14 2.34E-13 36 632 "SLAMF6,AACS,NCOA1,MPC2,FAM53A,CLOCK,NGDN,LACC1,VCAN,ZNF586,SREK1,LOC439933,ZNF419,NTN4,TRAPPC12,LGR6,DHRS2,ZNF671,DLEU1,SCYL2,SLC22A5,YPEL5,MYO16,NAAA,IKBIP,PPARGC1A,GJB2,DOCK9,HSD17B4,NSD2,YTHDC2,ZMYM2,LHX9,LOX,MICU2,ZNF304" MicroRNA hsa-miR-4312:mirSVR_lowEffct hsa-miR-4312:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.70E-15 3.03E-11 2.56E-14 2.34E-13 49 1146 "MATN3,SEMA6A,CUL4A,EP400,MSH2,CENPBD1P1,STARD13,MYH6,BTF3,CACNA1E,CAST,FCGR2C,PDE6B,WDFY2,AKAP6,GNPTAB,TOGARAM2,PM20D1,LRRTM2,CMTM5,CTSG,PSME1,DMXL1,NUDT12,LINC01257,RASA1,RGS4,TOMM40L,N4BP2L2,FLT1,SLC8A1,THADA,ARHGEF40,TADA1,WDCP,CD244,ATP8A2,RIPK3,KMT5A,NPL,HEXB,TXK,HPCAL1,HSD17B4,ZNF470,TTC41P,MFSD2B,LINC01913,AXDND1" MicroRNA hsa-miR-203a-3p.2:TargetScan hsa-miR-203a-3p.2 TargetScan 6.19E-15 3.29E-11 2.77E-14 2.54E-13 40 782 "KIAA1211,APBB2,APC,BCL2L2,NOVA1,CACNA1E,PCDH9,PDE4D,PDGFRA,GPR180,NUP37,HECTD1,HOMER1,CLOCK,MATR3,DNMT3A,RAN,MEMO1,MBNL2,MARVELD2,FBXO11,NBEA,IVNS1ABP,CCDC88A,NR5A2,FAM114A1,NMNAT2,PCDH17,LPIN1,ATP11A,SCFD1,GRSF1,MSH6,GTF2H3,PAPPA2,HTR2A,DCP2,FAM151B,KIF2A,LOX" MicroRNA hsa-miR-671-5p:mirSVR_highEffct hsa-miR-671-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.73E-15 3.58E-11 3.01E-14 2.76E-13 35 600 "SNX24,DHX37,APC,ATP4B,B4GALT3,BTF3,LINC02347,CBLN3,LDB2,FCGR2C,NFXL1,FAM177A1,PCSK1,RGSL1,CFL2,PIWIL1,POU2F1,NGDN,FCRL2,COG3,SACS,EIF2B1,FCAMR,CWC27,RELL1,SELP,SLC30A6,PKD2L2,CD244,SRP72,METAP2,ADGRA3,PLB1,KIT,PABPN1" MicroRNA hsa-miR-98-5p:Non-Functional MTI Non-Functional MTI miRTarbase 7.31E-15 3.89E-11 3.27E-14 2.99E-13 40 786 "MDM4,SNX24,B4GALT3,ATP7B,SLC5A6,CDK7,CDK17,CHD1,SNX6,GNPTAB,POU2F1,BRI3BP,CEP135,SNX17,TBC1D4,CEP120,SACS,MTX3,EGLN3,POLR1D,MBNL2,TBC1D19,GMPR2,PCGF3,TOMM40L,FOXO1,POTEM,PUS1,ZBTB37,PPARGC1A,STRN,MAST4,PSME4,UTP20,XPO4,BAZ1A,FZD10,GPN1,IGF1,NUAK2" MicroRNA hsa-miR-3190-5p:mirSVR_highEffct hsa-miR-3190-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.82E-15 4.16E-11 3.50E-14 3.20E-13 44 946 "DHX37,RAB29,NOVA1,FCGR2C,NFXL1,PCK2,PCSK1,RCBTB2,THAP6,POU2F1,LYSMD3,ZFYVE16,DMXL1,NR1H4,DNMT3A,ARGLU1,RGS12,SETDB2,KLHL12,CWC27,MAEA,TMEM156,SH3BP2,RUBCNL,CCDC92,SLC12A2,NPAS3,NFASC,CFHR4,LPIN1,PPARGC1A,UTP20,TMED2,ANO4,C5orf56,RIPK3,RAB2B,TNR,VRK2,KCNT2,CENPH,TDRD3,RNASE11,IFT88" MicroRNA hsa-miR-1271-5p:TargetScan hsa-miR-1271-5p TargetScan 7.91E-15 4.21E-11 3.53E-14 3.23E-13 42 866 "MAP1B,CUL4A,ASTN1,ATP2B4,NOVA1,CBLN3,CAMK4,CHAMP1,LDB2,SCARB1,CDK18,PDE4D,PDGFRA,PGGT1B,NUP37,BOD1L1,HOMER1,CLOCK,PREPL,COG3,DMXL1,NOP9,RASA1,NTN4,EFNA5,MBNL2,ETF1,DLEU1,FGF9,FOXO1,CCDC92,BRMS1L,CCDC88A,MYO16,GABRB1,NPAS3,PCDH17,GJA3,PSME4,DOCK9,C12orf73,LCP1" MicroRNA hsa-miR-96-5p:TargetScan hsa-miR-96-5p TargetScan 7.91E-15 4.21E-11 3.53E-14 3.23E-13 42 866 "MAP1B,CUL4A,ASTN1,ATP2B4,NOVA1,CBLN3,CAMK4,CHAMP1,LDB2,SCARB1,CDK18,PDE4D,PDGFRA,PGGT1B,NUP37,BOD1L1,HOMER1,CLOCK,PREPL,COG3,DMXL1,NOP9,RASA1,NTN4,EFNA5,MBNL2,ETF1,DLEU1,FGF9,FOXO1,CCDC92,BRMS1L,CCDC88A,MYO16,GABRB1,NPAS3,PCDH17,GJA3,PSME4,DOCK9,C12orf73,LCP1" MicroRNA hsa-miR-4265:mirSVR_lowEffct hsa-miR-4265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.00E-15 4.25E-11 3.57E-14 3.27E-13 55 1423 "RALGAPA1,ADORA1,WDR35,UVSSA,FAM193A,ATP4B,FCRL3,NRL,MPZL1,RILPL1,CD1E,PCK2,CDK18,RGSL1,CCDC122,ADGRF3,THAP6,ZNF586,IFT172,FBXL5,ATG10,OGFOD2,LATS2,KIRREL1,FAM172A,DLEU1,PCGF3,SLC22A17,PCBD2,FLT1,RASA3,C1orf112,HSPH1,CMPK2,PPIP5K2,GOLGA3,C5orf56,TCF7,RIPK3,ARHGEF28,STON1,NCSTN,NT5C1B,RASSF6,RIMBP2,IGSF8,VRK2,NSD2,KCNT2,ZFHX2,ZNF140,LHX9,CHPT1,EP400P1,LTA4H" MicroRNA hsa-miR-3169:mirSVR_highEffct hsa-miR-3169:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.58E-15 4.56E-11 3.82E-14 3.50E-13 37 677 "MATN3,MDM4,ADD1,NEDD8,ARHGEF7,ADGRD1,CAST,UHMK1,FCRLB,PDE4D,PDGFRA,VCAN,C12orf65,ITSN2,CEP135,CEP350,NUDT12,PARPBP,DNMT3A,AASDH,DHRS2,CWC27,ADGRV1,PIBF1,TMEM175,FBXO11,IVNS1ABP,CCDC88A,C1orf112,MYO16,SRP54,ANKLE2,LRCH1,PSME4,DOCK9,NT5C1B,FIP1L1" MicroRNA hsa-miR-4287:mirSVR_highEffct hsa-miR-4287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.62E-15 4.59E-11 3.84E-14 3.51E-13 40 790 "ABL2,NLN,DDX55,STARD13,PNP,CAST,SNTG2,VIT,GPR180,POU2F1,IFT172,SPATA18,LOC439933,TBC1D4,TSEN15,DNMT3A,DTD2,PACRGL,TXNDC15,GRTP1,ETF1,ARL6IP4,SUCO,FOXO1,ARHGEF40,SLC22A5,CHFR,MYT1L,UHRF1BP1L,SRP54,NCSTN,CRB1,GPR161,BAZ1A,ZNF10,ZMYM2,ZBED3-AS1,RILPL2,TTC41P,LCP1" MicroRNA hsa-miR-198:mirSVR_highEffct hsa-miR-198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.41E-15 5.00E-11 4.18E-14 3.83E-13 41 831 "NLN,CUL4A,PPP1R12B,CAST,LDB2,SLC5A8,CDK18,PDGFRA,CHD1,NRXN1,BOD1L1,JAKMIP1,PM20D1,SNCAIP,CSNK1G3,FCRL5,BIVM,PARPBP,NR1H4,SMC6,RGS12,NTN4,RNASEL,MBNL2,DLEU1,ABCA11P,HSD17B7,FBXO11,ALKAL2,IVNS1ABP,ZNF605,MRPS14,MEGF10,JPH4,ERAP1,METAP2,SLAIN1,TENT2,DCP2,ZMYM2,LINC00442" MicroRNA hsa-miR-450a:mirSVR_highEffct hsa-miR-450a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.55E-15 5.08E-11 4.24E-14 3.88E-13 26 319 "MATN3,SMIM15,KIAA1211,BLZF1,ATP12A,PCSK1,FAM53A,LOC439933,CEP350,RB1,ARSK,FNIP1,STAB2,ALKAL2,NR5A2,ZNF667,DCAF11,ZBTB37,ADGRA3,NT5C1B,LINC01551,RASSF6,GUF1,SLAIN1,RMST,LMNB1" MicroRNA hsa-miR-1262:mirSVR_lowEffct hsa-miR-1262:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.93E-15 5.28E-11 4.41E-14 4.04E-13 57 1523 "MDM4,ADD1,KIAA1211,WDR35,BLZF1,ATP2B4,LINC02347,XPR1,CDK7,CDK18,PDE6B,CCDC122,ITGBL1,POLN,THAP6,AKAP6,COPA,SNCAIP,FAM169A,DNM3,TSEN15,DNMT3A,RGS12,ZNF671,STK32B,SLC22A17,ELOVL7,FCAR,FGFR3,TACC3,POLK,SELP,FLT1,NBEA,PAICS,UFM1,C1orf112,NR5A2,MYT1L,KIF21B,PDS5B,NAAA,ZNF274,ATP8A2,HSPH1,KDM3B,DRC1,DHRS4,ZNF544,UTP20,ADAMTS19,UGT2B7,HTR2A,PLB1,KIR2DS4,KIT,LETM1" MicroRNA hsa-miR-377*:mirSVR_highEffct hsa-miR-377*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.00E-14 5.33E-11 4.45E-14 4.07E-13 34 573 "PITPNM2,NCOA1,AP1G2,NFXL1,FCRLB,PCK2,CENPC,PIK3C2B,THAP6,POU2F1,UBXN2A,FCRL5,ZNF586,PIGG,RASA1,ZNF419,NTN4,GP6,EFS,GORAB,FTLP10,MYT1L,NFASC,IKBIP,DOCK9,HAL,HEXB,TPO,STARD4,CHPT1,TMEM178A,DIAPH3,RMST,AXDND1" MicroRNA hsa-miR-192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-14 5.36E-11 4.46E-14 4.09E-13 45 994 "MDM4,APC,KCTD12,GAS2L3,CAMK4,MPZL1,ODC1,CFL2,RCBTB2,GPR180,POU2F1,LYSMD3,C12orf65,BIVM,COCH,DHFR,RNF219,ATG10,RB1,CLIP4,RNASEL,BORA,G2E3,ARHGEF40,N4BP2,TNFSF13B,WDCP,C1orf112,LIMCH1,CMPK2,NEDD1,NMU,TCF7,TDG,MSH6,TMPO,HSP90B1,UBE2K,NSD2,IL6ST,CHPT1,LMLN,CAB39L,LMNB1,SPATA13" MicroRNA hsa-miR-640:mirSVR_highEffct hsa-miR-640:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-14 5.49E-11 4.57E-14 4.18E-13 39 756 "MSH2,WDR19,CCNA1,NOVA1,TAF1B,CHAMP1,CD1E,UHMK1,SLC5A8,ZFYVE16,PIGG,COG3,NUDT12,TINF2,RABGAP1L,AASDH,EFNA5,RNF4,ELF1,KLHL12,DLEU1,F7,GORAB,FBXO11,NR5A2,TMEM183A,NFASC,ANKLE2,MAST4,ZNF544,ANO4,BAZ1A,HAL,RXFP2,ZMYM2,KIR2DL4,KIR2DS4,RMST,AXDND1" MicroRNA hsa-miR-135a-5p:TargetScan hsa-miR-135a-5p TargetScan 1.05E-14 5.56E-11 4.62E-14 4.23E-13 35 609 "MDM4,APC,NCOA1,ATP2B4,KCTD12,CADM3,BCL2L2,ARHGEF7,AP1G2,CACNA1E,FCHO2,LDB2,NFXL1,PCDH9,DCLK1,CHD1,PGGT1B,GPR180,CSNK1G3,DNM3,NOS1AP,REST,LATS2,ELK3,DNAJC27,FOXO1,NBEA,MYT1L,GABRB1,KDM5B,RAPGEF6,ANO4,DCP2,IL6ST,LMLN" MicroRNA hsa-miR-135b-5p:TargetScan hsa-miR-135b-5p TargetScan 1.05E-14 5.56E-11 4.62E-14 4.23E-13 35 609 "MDM4,APC,NCOA1,ATP2B4,KCTD12,CADM3,BCL2L2,ARHGEF7,AP1G2,CACNA1E,FCHO2,LDB2,NFXL1,PCDH9,DCLK1,CHD1,PGGT1B,GPR180,CSNK1G3,DNM3,NOS1AP,REST,LATS2,ELK3,DNAJC27,FOXO1,NBEA,MYT1L,GABRB1,KDM5B,RAPGEF6,ANO4,DCP2,IL6ST,LMLN" MicroRNA hsa-miR-338-3p:mirSVR_highEffct hsa-miR-338-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.06E-14 5.64E-11 4.68E-14 4.29E-13 41 834 "KIAA1211,B4GALT3,NOVA1,DAOA,CBLN3,UHMK1,VIT,TAPT1,GNPTAB,PM20D1,DNM3,UBXN2A,BIVM,COG3,G3BP2,ARGLU1,NTN4,PCGF3,USP44,NDUFAF7,FNIP1,RELL1,FLT1,HSD17B7,UFM1,LIMCH1,MYT1L,STRN,EML4,RNF212,TDG,ZBTB49,GTF2H3,HEXB,ZNF550,ZNF876P,CCDC190,ZMYM2,ZBED3-AS1,LCP1,RMST" MicroRNA hsa-miR-202:mirSVR_highEffct hsa-miR-202:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.13E-14 5.98E-11 4.97E-14 4.55E-13 37 683 "ABL2,KIAA1211,STARD13,PNP,CACNA1E,RCHY1,NGDN,VCAN,ZFYVE16,IFT172,SREK1,PTGS2,PPP2R3C,EGLN3,RB1,DTD2,DHRS2,BORA,ETF1,GMPR2,SELP,FMO1,TM9SF1,TADA1,SLC12A2,NPAS3,NEDD1,PPARGC1A,BAZ1A,GZMB,ATP6V0A2,KLF12,NLRP8,VRK2,C12orf73,KIF2A,LMNB1" MicroRNA hsa-miR-618:mirSVR_highEffct hsa-miR-618:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-14 6.40E-11 5.31E-14 4.86E-13 47 1083 "SLC4A4,KCTD12,FGFRL1,NOVA1,CHAMP1,ZNF664,CENPC,ZNF595,THAP6,HOMER1,TAPT1,GNPTAB,TOGARAM2,CEP135,PTPRC,TINF2,NR1I3,RGS4,CLIP4,POLR1D,ELF1,PCBD2,GORAB,FGF9,FGFR3,PIBF1,VEZT,FBXO11,NUBPL,TADA1,CCDC88A,GABRB1,MRPS27,ANKLE2,LRCH1,KLHL20,SULT1E1,BRD8,TMED2,SCFD1,FCRLA,MAEL,TXK,CCDC169,SPTSSA,KIT,AXDND1" MicroRNA hsa-miR-199a-3p:mirSVR_highEffct hsa-miR-199a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-14 6.46E-11 5.34E-14 4.89E-13 44 958 "MDM4,ARL1,ASTN1,NOVA1,CDKL2,DCLK1,CDK7,CDK17,PDGFRA,CFL2,PITX1,GNPTAB,FCRL5,GLT8D2,PTPRC,G3BP2,SUPT7L,PPP2R3C,DNMT3A,FAM129A,RB1,TMEM161B,RGS4,ELF1,MARVELD2,FAM172A,FCGR3A,FCGR3B,GORAB,FOXO1,CCDC88A,PKD2L2,UTP20,EML4,RNF17,MAEL,GUF1,DCP2,ZNF10,ZMYM2,TMEM178A,KCNN2,KIF2A,LOX" MicroRNA hsa-miR-199b-3p:mirSVR_highEffct hsa-miR-199b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-14 6.46E-11 5.34E-14 4.89E-13 44 958 "MDM4,ARL1,ASTN1,NOVA1,CDKL2,DCLK1,CDK7,CDK17,PDGFRA,CFL2,PITX1,GNPTAB,FCRL5,GLT8D2,PTPRC,G3BP2,SUPT7L,PPP2R3C,DNMT3A,FAM129A,RB1,TMEM161B,RGS4,ELF1,MARVELD2,FAM172A,FCGR3A,FCGR3B,GORAB,FOXO1,CCDC88A,PKD2L2,UTP20,EML4,RNF17,MAEL,GUF1,DCP2,ZNF10,ZMYM2,TMEM178A,KCNN2,KIF2A,LOX" MicroRNA hsa-let-7c*:mirSVR_highEffct hsa-let-7c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-14 6.69E-11 5.54E-14 5.07E-13 44 959 "RALGAPA1,MDM4,SEMA6A,BLZF1,ARL1,CADM3,FCHO2,PDGFRA,SNX6,BOD1L1,JAKMIP1,ITSN2,KIAA0040,NOS1AP,GLT8D2,OCIAD1,RASA1,ARGLU1,TMEM161B,DTD2,NTN4,TXNDC15,MBNL2,ELF1,TBC1D19,DRAM1,FNIP1,PEAR1,FOXO1,G2E3,UFM1,IVNS1ABP,THADA,ZNF605,YPEL5,MYO16,ERAP1,ERBIN,IKBIP,NPFFR2,TFDP1,NPL,LCP1,IFT88" MicroRNA hsa-miR-597:mirSVR_lowEffct hsa-miR-597:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-14 6.91E-11 5.71E-14 5.23E-13 55 1440 "MDM4,ADD1,HOMEZ,APBB2,ZNF784,WDR19,FAM193A,SLC4A4,ZNF542P,BTF3,TAF1B,SCARB1,WDFY2,ITGBL1,PIGR,UGT2B28,HOMER1,AKAP6,HEATR5A,KIAA0040,DCAF8,ZFYVE16,NUDT12,PTPRH,TINF2,RABGAP1L,B3GLCT,EFNA5,TMEM129,FCAR,N4BP2L2,NUBPL,SLC30A6,TADA1,UGGT2,GABRA2,MYT1L,KDM5B,HSPH1,LRCH1,PPARGC1A,PPIP5K2,METAP2,ADGRA3,ANO4,ACSL6,DOCK9,YIPF7,RNF17,NT5C1B,ACTR6,GPN1,NSD2,KCNT2,LMNB1" MicroRNA hsa-miR-4279:mirSVR_highEffct hsa-miR-4279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.31E-14 6.94E-11 5.73E-14 5.25E-13 44 960 "ABL2,NCOA1,PNP,CACNA1E,ITGBL1,PMCH,THTPA,NGDN,ZNF586,ZFYVE16,PIGG,COCH,DHFR,OGFOD2,AASDH,GUSBP3,PACRGL,TXNDC15,MBNL2,PCGF3,FCAR,NDUFAF7,PIBF1,YPEL5,TMEM183A,NPAS3,MRPS27,DRC1,PCDH17,ZBTB37,METAP2,ANO4,ARHGEF28,DOCK9,NT5C1B,TNR,TXK,PLB1,SPTSSA,ZMYM2,LHX9,AXDND1,LMNB1,PABPN1" MicroRNA hsa-miR-215:mirSVR_highEffct hsa-miR-215:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.35E-14 7.20E-11 5.94E-14 5.44E-13 34 579 "MDM4,ANKRD34B,ARHGAP5,ARL1,PCCA,PCDH9,SNX6,BOD1L1,THAP6,HEATR5A,PRKD1,SREK1,CEP350,RB1,SETDB2,ABCA11P,FBXO11,LIMCH1,KIF21B,KDM5B,CENPJ,KLHL20,INSM2,ADGRL3,C5orf56,TDG,RAB2B,ZNF721,PAPPA2,VRK2,NSD2,JCHAIN,KCNN2,AXDND1" MicroRNA hsa-miR-192:mirSVR_highEffct hsa-miR-192:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.35E-14 7.20E-11 5.94E-14 5.44E-13 34 579 "MDM4,ANKRD34B,ARHGAP5,ARL1,PCCA,PCDH9,SNX6,BOD1L1,THAP6,HEATR5A,PRKD1,SREK1,CEP350,RB1,SETDB2,ABCA11P,FBXO11,LIMCH1,KIF21B,KDM5B,CENPJ,KLHL20,INSM2,ADGRL3,C5orf56,TDG,RAB2B,ZNF721,PAPPA2,VRK2,NSD2,JCHAIN,KCNN2,AXDND1" MicroRNA hsa-miR-3188:mirSVR_lowEffct hsa-miR-3188:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-14 7.49E-11 6.17E-14 5.65E-13 60 1678 "ADD1,RGS5,ZNF784,NOP14,CENPBD1P1,ATP2B4,LINC02347,NOVA1,CBLN3,MPZL1,CAST,CDK18,DHRS1,WDFY2,SNX6,ADGRF3,POLN,AKAP6,TOGARAM2,POU2F1,CSNK1G3,KLHL3,TINF2,G3BP2,SUPT7L,SLC35F6,B3GLCT,PACRGL,KIRREL1,MPHOSPH9,DLEU1,DNAJC27,LRRN2,TNFRSF19,FBXO11,PKD2L2,CHFR,KIF21B,TMEM183A,OXGR1,NPAS3,NFASC,LILRB1,TBC1D1,GPR12,ARHGEF28,STON1,FCRLA,TEP1,CRB1,GTF2H3,MAEL,IGSF8,ADAMTS19,UGT2B7,VRK2,ZNF470,PLB1,NUAK2,LIG4" MicroRNA hsa-miR-3065-3p:mirSVR_highEffct hsa-miR-3065-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-14 7.73E-11 6.36E-14 5.82E-13 41 842 "MDM4,BIRC6,CDKL4,MSH2,NFATC4,LINC02347,ODC1,SNTG2,SLC5A8,CENPC,VIT,CFAP54,NRXN1,JAKMIP1,PTPRVP,POU2F1,CLOCK,C12orf65,BIVM,SACS,RNASEL,LGR6,BORA,SH3YL1,NDUFAF7,FGF9,NBEA,NUBPL,SLC8A1,GABRA2,PDS5B,NAAA,SRP72,PCDH17,STRN,PSME4,ACSL6,HMGCR,KCNN2,LMNB1,LOX" MicroRNA hsa-miR-1262:mirSVR_highEffct hsa-miR-1262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.59E-14 8.45E-11 6.95E-14 6.36E-13 40 805 "RALGAPA1,NYNRIN,ULK1,CDKL4,ARHGEF7,AP1G2,NOVA1,CAST,CD1E,PCCA,PCSK1,RGSL1,PDE4D,ZNF595,PIK3C2B,JAKMIP1,RNASE9,BIVM,DMXL1,DHX9,DHFR,RNF31,TMEM161B,MBNL2,DRAM1,F10,SLC8A1,CD244,INSM2,ADGRL3,ARHGEF28,RNF212,LINC01551,BAZ1A,HSD17B4,VRK2,ZMYM2,LINC00272,LHX9,ZBED3-AS1" MicroRNA hsa-miR-199b-3p:TargetScan hsa-miR-199b-3p TargetScan 1.70E-14 9.03E-11 7.42E-14 6.79E-13 27 356 "ABL2,MCFD2,NCOA1,ASTN1,NOVA1,CAD,CDK7,CDK17,PDGFRA,CFL2,ATAD2B,GNPTAB,POU2F1,KLHL3,G3BP2,DNMT3A,RB1,SBNO1,CCDC88A,IQGAP2,PCDH17,EML4,MSH6,KLF12,DCP2,IGF1,LOX" MicroRNA hsa-miR-199a-3p:TargetScan hsa-miR-199a-3p TargetScan 1.70E-14 9.03E-11 7.42E-14 6.79E-13 27 356 "ABL2,MCFD2,NCOA1,ASTN1,NOVA1,CAD,CDK7,CDK17,PDGFRA,CFL2,ATAD2B,GNPTAB,POU2F1,KLHL3,G3BP2,DNMT3A,RB1,SBNO1,CCDC88A,IQGAP2,PCDH17,EML4,MSH6,KLF12,DCP2,IGF1,LOX" MicroRNA hsa-miR-486-3p:mirSVR_highEffct hsa-miR-486-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.84E-14 9.76E-11 8.01E-14 7.33E-13 37 694 "LRRC43,MDM4,KIAA1211,ATP4B,NEDD8,NFATC4,CAD,CDK18,CEP135,FCRL5,DCAF8,COG3,TBC1D4,G3BP2,TXNDC15,KIRREL1,KLHL12,FCAMR,STK32B,DLEU1,PCGF3,TMEM175,CIDEB,NAAA,TMEM183A,NEDD1,UTP20,ANO4,DOCK9,LINC01551,RAB2B,YTHDC2,SDR39U1,TMEM178A,KIR2DL1,LAD1,PABPN1" MicroRNA hsa-miR-548v:mirSVR_highEffct hsa-miR-548v:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-14 1.03E-10 8.41E-14 7.70E-13 39 771 "RALGAPA1,SMIM15,CDKL4,NOVA1,PCSK1,PDE6B,CFL2,PGGT1B,MPC2,SNCAIP,LRRTM2,ZFYVE16,IFT172,LOC439933,CEP350,CEP120,ETF1,SELP,SLC8A1,CGREF1,TNFSF13B,SF3B6,MRPS14,NR5A2,CHFR,KDM5B,CENPJ,GJB6,ANO4,TEP1,CRB1,ZBTB49,HMGCR,GUF1,SPTSSA,KIT,LCP1,RMST,PABPN1" MicroRNA hsa-miR-3115:mirSVR_lowEffct hsa-miR-3115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-14 1.03E-10 8.44E-14 7.73E-13 44 971 "ATP1A2,SLC4A4,ZNF542P,NOVA1,PAH,CCDC122,THAP6,SNCAIP,ITSN2,IFT172,COG3,DMXL1,PTPRH,RB1,CLIP4,MEMO1,ZNF419,EFNA5,MBNL2,GP6,ARSK,CWC27,UTP15,FNIP1,PIBF1,SUCO,SELP,FLT3,FMO1,PLEKHA6,DCAF11,SNRPF,UHRF1BP1L,ERAP1,MRPS27,KDM3B,MCCC2,TFDP1,TMPO,NLRP8,LHX9,TTC41P,SPRYD7,SKA3" MicroRNA hsa-miR-452:PITA hsa-miR-452:PITA_TOP PITA 1.94E-14 1.03E-10 8.45E-14 7.74E-13 30 451 "MAP1B,PCSK1,PDE4D,CENPC,ATAD2B,ANAPC4,STRN3,TAPT1,MATR3,CEP350,G3BP2,ARGLU1,CLIP4,MPHOSPH9,DEPDC4,FBXO11,G2E3,MYT1L,SRP54,ERBIN,PCDH17,PPIP5K2,DOCK9,RIMBP2,MAEL,KLF12,NSD2,IGF1,ZBTB41,KIT" MicroRNA hsa-miR-137:PITA hsa-miR-137:PITA_TOP PITA 2.03E-14 1.08E-10 8.84E-14 8.09E-13 32 518 "TMEM132B,CUL4A,PITPNM2,ARHGAP5,KCTD12,ARHGEF7,NOVA1,DCLK1,PDE4D,ATAD2B,CSNK1G3,ZFYVE16,TMEM33,RNF4,MBNL2,TBC1D19,FAM172A,RELL1,NBEA,SLC8A1,SLC12A2,KDM5B,NFASC,ERBIN,PPARGC1A,TBC1D1,ACSL6,XPO4,BAZ1A,KLF12,SLAIN1,KIT" MicroRNA hsa-miR-153-3p:TargetScan hsa-miR-153-3p TargetScan 2.04E-14 1.09E-10 8.86E-14 8.12E-13 35 623 "ADD1,FBRSL1,APBB2,APC,ATP2B4,CADM3,PPP1R12B,NOVA1,DCLK1,FAM177A1,PDE4D,CFL2,CHD1,ATAD2B,BOD1L1,AKAP6,RCHY1,POU2F1,ITSN2,DNM3,CEP350,KLHL3,RASA1,REST,FOXO1,NBEA,BRMS1L,ARHGEF40,NR5A2,NMNAT2,NFASC,LRCH1,PPARGC1A,DCP2,LHX9" MicroRNA hsa-miR-3157:mirSVR_highEffct hsa-miR-3157:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-14 1.10E-10 8.94E-14 8.19E-13 42 891 "TBC1D14,CUL4A,FGFRL1,BTF3,NOVA1,PCK2,CDK18,PDE4D,CEBPE,PDGFRA,CHD1,ADGRF3,AKAP6,ZFYVE16,SPATA18,PIGG,COG3,FBXL5,WDR1,TSEN15,RNF219,NR1H4,ARGLU1,ZNF329,RNASEL,LATS2,DHRS2,NDUFAF7,FGF9,RELL1,PIBF1,SDC1,SUPT20H,PKD2L2,MRPS14,RAPGEF6,NAAA,DRC1,ADAM17,ZNF470,LINC00272,RMST" MicroRNA hsa-miR-383:mirSVR_highEffct hsa-miR-383:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.10E-14 1.11E-10 9.09E-14 8.32E-13 46 1057 "SMIM15,UVSSA,MSH2,CD84,NOVA1,CD1E,SLC5A8,CDK18,RCBTB2,CFAP54,LINC01085,THAP6,AKAP6,STRN3,LRRTM2,FCRL5,FCRL2,SPATA18,SREK1,FBXL5,CEP350,EIF2D,RNASEL,FAM172A,FGF9,POLK,HSD17B7,VEZT,PAICS,IVNS1ABP,TADA1,SLC22A5,GABRA2,NAAA,CMPK2,ANKLE2,PCDH17,TBC1D1,ADGRL3,CRB1,TECRL,HTR2A,IRF1,DIAPH3,SPRYD7,LMNB1" MicroRNA hsa-miR-369-3p:PITA hsa-miR-369-3p:PITA_TOP PITA 2.11E-14 1.12E-10 9.15E-14 8.38E-13 33 553 "RALGAPA1,MAP1B,MCFD2,ARHGAP5,ARHGEF7,SLC5A8,CDK17,PDE4D,CFL2,HOMER1,ZFYVE16,COG3,CEP350,KLHL3,MBNL2,FAM172A,FNIP1,FOXG1,FOXO1,SFSWAP,G2E3,ALKAL2,NR5A2,MYO16,MEGF10,PDS5B,HSPH1,STON1,ZBTB49,BAZ1A,ADAMTS19,KLF12,LHX9" MicroRNA hsa-miR-151-3p:mirSVR_highEffct hsa-miR-151-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-14 1.18E-10 9.59E-14 8.79E-13 34 589 "ADD1,ANKRD34B,ARL1,CAST,UHMK1,FCRLB,TAPT1,POU2F1,EPGN,CEP135,PTGS2,C14orf119,DNMT3A,POLR1D,MBNL2,NDUFAF7,SUCO,GFM2,SCYL2,IVNS1ABP,THADA,CCDC88A,GABRB1,HSPH1,NPAS3,ANKLE2,LRCH1,ERBIN,BRD8,RAB2B,FZD10,NPL,LIG4,LMNB1" MicroRNA hsa-miR-548k:PITA hsa-miR-548k:PITA_TOP PITA 2.38E-14 1.27E-10 1.03E-13 9.44E-13 32 521 "TBC1D14,CUL4A,SLC4A4,NFKBIA,NOVA1,MPZL1,UHMK1,XPR1,CDK17,CHD1,CSNK1G3,MATR3,CEP120,MAEA,ETF1,RELL1,NBEA,SLC30A6,IVNS1ABP,TADA1,CCDC88A,MYT1L,PDS5B,KMT5A,DOCK9,NCSTN,GRSF1,RIMBP2,GPN1,DCP2,SPTSSA,ZBTB41" MicroRNA hsa-miR-3130-5p:mirSVR_lowEffct hsa-miR-3130-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.41E-14 1.28E-10 1.04E-13 9.56E-13 50 1235 "COG6,RGS5,APC,ATP2B4,FGFRL1,NEDD8,NRL,CAST,CD1D,FCRLB,PDE4D,PDE6B,ITGBL1,CFAP54,SMIM14,GNPTAB,SPATA18,EPS8L1,PIGG,COG3,OCIAD1,RABGAP1L,GNPDA2,RNF219,NR1H4,RB1,RGS12,PACRGL,MARVELD2,EFS,SLC22A17,FCGR2B,TOMM40L,TNFRSF19,SUCO,FBXO11,THADA,C1orf112,RAPGEF6,TMEM183A,ZNF274,ATP8A2,LRCH1,PSME4,CNTN2,ANO4,DOCK9,LINC01551,MZF1,ZNF304" MicroRNA hsa-miR-4309:mirSVR_highEffct hsa-miR-4309:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-14 1.31E-10 1.06E-13 9.74E-13 35 627 "ADCY4,APC,ZNF784,BLZF1,ASCL1,NFATC4,DAOA,SCFD2,CHIT1,CPNE6,LTB4R,STRN3,HEATR5A,SNCAIP,LACC1,VCAN,LRRTM2,UBXN2A,CEP350,TINF2,RB1,EIF2D,FGF9,KDM5B,FAM114A1,ERAP1,KDM3B,DOCK9,CRB1,TMPO,ADAMTS19,GPN1,GUF1,VRK2,LINC01913" MicroRNA hsa-miR-218-5p:Non-Functional MTI Non-Functional MTI miRTarbase 2.46E-14 1.31E-10 1.06E-13 9.74E-13 40 816 "BIRC6,APC,ATP2B4,ODC1,WDR66,PDGFRA,PIK3C2B,RCHY1,THTPA,VCAN,DCAF8,SREK1,FBXL5,SACS,WDR1,RNF219,RNF4,SBNO1,MBNL2,EIF2B1,FAM172A,FNIP1,SFSWAP,FSHR,ACIN1,UGGT2,KIF21B,MRPS27,PSME4,ADAM17,GOLGA3,KMT5A,DOCK9,KLF12,HSP90B1,STARD4,DCP2,KIT,NUAK2,LMNB1" MicroRNA hsa-miR-4303:mirSVR_highEffct hsa-miR-4303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.51E-14 1.34E-10 1.08E-13 9.92E-13 38 739 "APC,HOMER1,TOGARAM2,DNM3,UBXN2A,PIGG,CEP350,C12orf42,NR1I3,FAM129A,PACRGL,MPHOSPH9,LGR6,DHRS2,FAM172A,EFS,FCGR3A,FCGR3B,FNIP1,FGF9,SUCO,FLT1,SLC12A2,YPEL5,GABRA2,NPAS3,GJB2,MAST4,TMED2,METAP2,C5orf56,GTF3C2,RIMBP2,ZNF470,PLB1,ZBED3-AS1,TTC41P,LINC01913" MicroRNA hsa-miR-500*:mirSVR_highEffct hsa-miR-500*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.69E-14 1.43E-10 1.16E-13 1.06E-12 34 593 "RALGAPA1,MATN3,NDRG2,APAF1,ARL1,AACS,PPP1R12B,CDKL2,CAMK4,FAM177A1,PDE4D,CHD1,LINC01085,CFAP45,BOD1L1,MATR3,SREK1,SACS,POLR1D,FCAMR,ABCA11P,CLIP1,FOXG1,NBEA,PDS5B,DHRS4,ZNF544,DOCK9,RNF17,MAEL,ZNF721,GUF1,TENT2,KIR3DL2" MicroRNA hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 2.82E-14 1.50E-10 1.21E-13 1.11E-12 26 334 "ABL2,PITPNM2,NCOA1,ATP1A2,CACNA1E,PDE4D,PDGFRA,CFL2,PGGT1B,PIGR,AKAP6,POU2F1,CLOCK,PIGG,DMXL1,REST,ELOVL7,FGF9,NR5A2,GABRB1,ATP8A2,NPAS3,PCDH17,PPARGC1A,DCP2,DIAPH3" MicroRNA hsa-miR-1183:mirSVR_highEffct hsa-miR-1183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-14 1.51E-10 1.22E-13 1.12E-12 46 1066 "KIAA1211,APC,ARHGEF7,CCNA1,CDKL2,CD1D,ZNF664,CFL2,ZNF595,HECTD1,LACC1,GLT8D2,PARPBP,PPP2R3C,DNMT3A,LGR6,DEPDC4,SUCO,N4BP2,FSHR,CHFR,UGGT2,PDS5B,TMEM183A,ERAP1,IKBIP,KLHL20,PCDH17,ZBTB37,PPARGC1A,PSME4,LINC02393,SCFD1,ANO4,BAZ1A,ACTR6,MAEL,TPO,GUF1,NSD2,KCNT2,IL6ST,CCDC169,PLB1,ZMYM2,SPRYD7" MicroRNA hsa-miR-1827:mirSVR_highEffct hsa-miR-1827:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.87E-14 1.53E-10 1.24E-13 1.13E-12 45 1024 "MCC,EP400,PPFIA4,FGFRL1,FCHO2,CDK18,PDGFRA,ZNF595,WDFY2,GPR180,NGDN,EIF2AK2,DCAF8,SPATA18,SREK1,COG3,CEP350,SLC35F6,LINC01257,WDR1,EGLN3,EIF2D,SUCO,HSD17B7,VEZT,NLRP2,SCYL2,THADA,GABRB1,IQGAP2,KDM3B,SRP72,PSME4,TMED2,ANO4,NCSTN,STARD4,MZF1,CENPH,ZNF470,FAM49A,KIR2DS4,KIR3DL2,AMTN,NUAK2" MicroRNA hsa-miR-2861:mirSVR_lowEffct hsa-miR-2861:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.12E-14 1.66E-10 1.34E-13 1.23E-12 58 1613 "MDM4,NLN,SLAMF6,HOMEZ,PPFIA4,APAF1,ASCL1,NCOA1,MYBPC1,KCTD12,CBLN3,FCRLB,DCLK1,CHD1,PFKFB2,VIT,CHIT1,GNPTAB,NOS1AP,DCAF8,EPS8L1,C14orf119,NR1I3,FAM129A,RNF31,OGFOD2,RGS12,EIF2D,DHRS2,ARSK,STK32B,MAEA,TOMM40L,SULT6B1,FOXO1,VEZT,STPG4,ARHGEF40,KDM5B,ZNF274,CD244,CNTN2,LILRB4,C5orf56,NCSTN,TEP1,CRB1,AP4S1,ARHGAP30,LTB4R2,WDR36,PLB1,IRF1,ZBED3-AS1,DIAPH3,MFSD2B,LINC01913,AXDND1" MicroRNA hsa-miR-222:mirSVR_highEffct hsa-miR-222:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.12E-14 1.66E-10 1.34E-13 1.23E-12 40 822 "RALGAPA1,MAP1B,WDR35,PITPNM2,APAF1,WDR19,NOVA1,UHMK1,CDK18,PFKFB2,ZNF595,GPR180,COLEC11,ATAD2B,POU2F1,KIAA0040,ZFYVE16,NUDT12,SUPT7L,TSEN15,RGS4,MARVELD2,ARSK,PCGF3,FGF9,PIBF1,SUCO,FBXO11,CCDC88A,PKD2L2,SF3B6,PPARGC1A,BRD8,ADAM17,ZBTB49,TXK,GUF1,SPTSSA,KIR3DL1,KIT" MicroRNA hsa-miR-203a-3p.1:TargetScan hsa-miR-203a-3p.1 TargetScan 3.29E-14 1.75E-10 1.41E-13 1.29E-12 36 670 "ABL2,KIAA1211,APC,CD84,NOVA1,PDE4D,CFL2,GPR180,NUP37,HECTD1,CLOCK,EIF2AK2,MATR3,FBXL5,DNMT3A,MBNL2,MARVELD2,ETF1,NDUFAF7,FNIP1,NBEA,IVNS1ABP,CCDC88A,KIF21B,FAM114A1,NMNAT2,ATP8A2,PCDH17,LPIN1,ATP11A,DOCK9,GRSF1,GUF1,DCP2,IRF1,KIF2A" MicroRNA hsa-miR-1225-3p:mirSVR_lowEffct hsa-miR-1225-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-14 1.81E-10 1.46E-13 1.34E-12 48 1158 "NDRG2,BIRC6,ATP6V1G3,TBC1D14,ARHGAP5,ASCL1,ATP4B,NFATC4,CPNE6,SMIM14,PTPRVP,TAPT1,FAM53A,ITSN2,DCAF8,SNX17,EPS8L1,EGLN3,ZNF329,AASDH,FAM228A,DTD2,RGS12,TMEM33,GUSBP3,SPATA9,LGR6,FCAMR,EFS,DLEU1,FCAR,UFM1,EFR3B,MYT1L,CIDEB,NPAS3,NFASC,SRP72,MCCC2,AURKC,LILRB4,ANO4,GTF3C2,ATP6V0A2,GPN1,ZNF10,KCNJ9,ZNF304" MicroRNA hsa-miR-541:mirSVR_lowEffct hsa-miR-541:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-14 1.82E-10 1.47E-13 1.34E-12 60 1713 "SFTA3,LRRC43,TMEM132B,ADD1,ACOX3,COG6,HOMEZ,ATP1A2,CADM3,LINC02347,CD1D,CDK18,PDE6B,PKP1,SNCAIP,NR1I3,DNMT3A,ZNF329,AASDH,MBNL2,LGR6,TCTN2,FAM172A,STK32B,F7,PCBD2,TMEM129,RELL1,POLK,PEAR1,STAB2,SH3BP2,DDX51,POTEM,EFR3B,PUS1,KIF21B,ATP8A2,NFASC,SRP72,RBKS,ANKLE2,ADGRL3,C5orf56,TEP1,SLC7A8,AP4S1,NPL,ADAMTS19,RXFP2,FCRL6,ZNF470,C12orf73,ZBED3-AS1,KIF3C,KIR2DL1,KIR2DS4,KIR3DL1,AXDND1,CDK2AP1" MicroRNA hsa-miR-2114*:mirSVR_highEffct hsa-miR-2114*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-14 1.87E-10 1.50E-13 1.38E-12 29 429 "BIRC6,COG6,DAOA,CDK18,GNPTAB,DDX59,SREK1,COG3,NR1I3,RNASEL,LIMCH1,CYP1B1-AS1,GABRA2,RAPGEF6,NAAA,LRCH1,GJB2,PSME4,ZBTB49,GTF3C2,MAEL,JCHAIN,SPTSSA,KCNN2,KIR2DL1,KIR2DL4,KIR3DL1,KIR3DL2,LINC00442" MicroRNA hsa-miR-548b-3p:PITA hsa-miR-548b-3p:PITA_TOP PITA 4.15E-14 2.21E-10 1.77E-13 1.63E-12 22 230 "SEMA6A,ATP2B4,CDKL2,FCHO2,LDB2,UHMK1,PIK3C2B,ATAD2B,HOMER1,MATR3,SMC6,LATS2,STX2,FGF9,NBEA,NR5A2,NPAS3,KLHL20,PPARGC1A,RAB2B,ZMYM2,ZBTB41" MicroRNA "TACTTGA,MIR-26B:MSigDB" "TACTTGA,MIR-26B:MSigDB" MSigDB 4.24E-14 2.26E-10 1.81E-13 1.66E-12 24 283 "ULK1,EP400,APC,ATP1A2,SLC4A4,PCDH9,PDGFRA,AKAP6,PTGS2,DMXL1,TBC1D4,SACS,G3BP2,RGS4,TMEM33,NTN4,FBXO11,SLC12A2,CHFR,GTF3C2,TENT2,HTR2A,IGF1,CDK2AP1" MicroRNA "TACTTGA,MIR-26A:MSigDB" "TACTTGA,MIR-26A:MSigDB" MSigDB 4.24E-14 2.26E-10 1.81E-13 1.66E-12 24 283 "ULK1,EP400,APC,ATP1A2,SLC4A4,PCDH9,PDGFRA,AKAP6,PTGS2,DMXL1,TBC1D4,SACS,G3BP2,RGS4,TMEM33,NTN4,FBXO11,SLC12A2,CHFR,GTF3C2,TENT2,HTR2A,IGF1,CDK2AP1" MicroRNA hsa-miR-18a*:mirSVR_lowEffct hsa-miR-18a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-14 2.30E-10 1.85E-13 1.69E-12 63 1870 "ABL2,KIAA1211,SNX24,PPFIA4,ASTN1,CCDC181,BCL2L2,NFATC4,ARHGEF7,BTF3,CD1D,CD1E,SNTG2,PDE4D,CEBPE,GPR180,PIK3C2B,RCHY1,FCRL5,EPS8L1,DNMT3A,ZNF329,DTD2,EFNA5,RNF4,MBNL2,DRAM1,SAP18,DLEU1,GORAB,ZNF605,CGREF1,SLC22A4,CYP1B1-AS1,GABRB1,PDS5B,NMNAT2,TMEM183A,OXGR1,NFASC,RBKS,LILRB1,MAST4,ZNF544,PPIP5K2,ADGRL3,C5orf56,RIPK3,ARHGEF28,COX18,FCRLA,SLC7A8,HAL,NPL,ARHGAP30,HSD17B4,DCP2,LHX9,KCNJ9,ANKDD1B,EP400P1,MFSD2B,SPRYD7" MicroRNA hsa-miR-19b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-14 2.32E-10 1.86E-13 1.70E-12 37 714 "MCC,PDE4D,CFL2,WDFY2,PITX1,HOMER1,GNPTAB,CLOCK,DCAF8,SNX17,CEP350,KLHL3,TBC1D4,G3BP2,MTX3,WDR1,RAN,EGLN3,RASA1,MBNL2,MPHOSPH9,CLIP1,PAICS,GAK,RAPGEF6,KLHL20,ZNF544,ARHGEF28,GRSF1,RAB2B,ZNF721,SLAIN1,TENT2,DCP2,SPTSSA,ZMYM2,LMLN" MicroRNA hsa-miR-1308:mirSVR_lowEffct hsa-miR-1308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.37E-14 2.32E-10 1.86E-13 1.70E-12 49 1210 "CDKL4,NOVA1,WDFY2,CFAP54,PIGR,ATAD2B,ADGRF3,POLN,PTPRVP,THAP6,COPA,IFT172,SACS,EGLN3,RB1,POLR1D,LATS2,RNF4,MBNL2,FCAMR,DRAM1,ETF1,GORAB,TNFRSF19,FLT1,FBXO11,PAICS,UFM1,MEGF10,KIF21B,CENPJ,KDM3B,GCKR,ADAM17,PPIP5K2,ANO4,XPO4,RNF17,TFDP1,LINC01551,TMPO,LTB4R2,TXK,LHX9,KIT,TTC41P,LINC01913,LETM1,LTA4H" MicroRNA hsa-miR-6835-3p:TargetScan hsa-miR-6835-3p TargetScan 4.48E-14 2.38E-10 1.91E-13 1.75E-12 36 677 "ABL2,MAP1B,BIRC6,APC,ATP2B4,CAMK4,FAM177A1,CFL2,GPR180,NRXN1,PKP1,LYSMD3,BRI3BP,DCAF8,MATR3,COG3,DMXL1,MTX3,DNMT3A,REST,POLR1D,FLT1,N4BP2,KDM5B,FAM114A1,NPAS3,PCDH17,LPIN1,PPARGC1A,GJA3,PPIP5K2,GRSF1,HTR2A,DCP2,IL6ST,LMLN" MicroRNA hsa-miR-1826:mirSVR_lowEffct hsa-miR-1826:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.91E-14 2.61E-10 2.09E-13 1.91E-12 53 1395 "MAP1B,ADD1,WDR35,SEMA6A,SNX24,TAF1B,CD1E,DCLK1,XPR1,CDK17,RCBTB2,VIT,SLC25A3,ITGBL1,BOD1L1,HECTD1,MPC2,RCHY1,LYSMD3,ITSN2,KIAA0040,PIGG,PTGS2,TMEM161B,RGS4,EFNA5,GRTP1,PCGF3,TRAPPC13,TMEM156,GORAB,FNIP1,VEZT,PLEKHA6,SLC12A2,NR5A2,CENPJ,SCFD1,MTUS2,ADGRL3,LILRB4,GPR12,DOCK9,COX18,GRSF1,RAB2B,MAEL,TXK,ZNF470,IL6ST,PLB1,KCNN2,CAB39L" MicroRNA hsa-miR-3179:mirSVR_highEffct hsa-miR-3179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-14 2.73E-10 2.18E-13 2.00E-12 41 875 "NYNRIN,HOMEZ,APC,NCOA1,NLRP4,NOVA1,SLC5A8,ZNF664,PCDH9,ADGRF3,AKAP6,LYSMD3,COG3,TSEN15,FAM228A,SLC9C2,RNASE2,RNF4,DNAJC27,F10,PIBF1,SELP,TM9SF1,IVNS1ABP,SLC8A1,CCDC88A,WDCP,JPH4,ZBTB37,GJB2,METAP2,ADGRL3,RAB2B,HSP90B1,ZNF10,CCDC169,FAM151B,FAM49A,KIT,RILPL2,PABPN1" MicroRNA hsa-miR-362-5p:mirSVR_highEffct hsa-miR-362-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.52E-14 2.93E-10 2.34E-13 2.14E-12 38 758 "CDKL2,CAST,UHMK1,GPR180,PIK3C2B,JAKMIP1,THAP6,AKAP6,STRN3,LACC1,UBXN2A,ZFYVE16,OCIAD1,RABGAP1L,PARPBP,PACRGL,FAM172A,ADGRV1,PCGF3,NDUFAF7,FGF9,TADA1,ZNF605,RAPGEF6,HSPH1,KLHL20,UGT2A1,ANO4,TPO,KLF12,UBE2K,GUF1,IGF1,KCNT2,KIF3C,SLAMF9,RMST,LTA4H" MicroRNA hsa-miR-626:mirSVR_highEffct hsa-miR-626:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.62E-14 2.99E-10 2.38E-13 2.18E-12 37 720 "MAP1B,WDR35,WDR19,ODC1,PCDH9,RGSL1,PDE4D,ZNF595,AKAP6,CSNK1G3,VCAN,UBXN2A,FBXL5,DHFR,DTD2,SETDB2,CWC27,FGF9,POLK,SDC1,SUPT20H,TM9SF1,SLC22A4,ERBIN,IKBIP,PPARGC1A,GTF2H3,TMPO,HEXB,GUF1,SLAIN1,IGF1,LINC00272,KCNJ9,FIP1L1,KIF2A,RMST" MicroRNA hsa-let-7a:mirSVR_highEffct hsa-let-7a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.72E-14 3.04E-10 2.43E-13 2.22E-12 39 798 "MDM4,SLAMF6,HOMEZ,WDR19,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RB1,RGS12,CWC27,PCGF3,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,MAST4,ACSL6,CRB1,PAPPA2,ZNF10,KIF2A,SPRYD7,AXDND1" MicroRNA hsa-miR-890:mirSVR_highEffct hsa-miR-890:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.86E-14 3.11E-10 2.48E-13 2.27E-12 46 1088 "RALGAPA1,MATN3,MDM4,MSH2,BLZF1,NCOA1,FCRL3,CDKL2,NRXN1,BOD1L1,THAP6,LYSMD3,CSNK1G3,MATR3,SREK1,COG3,FBXL5,SUPT7L,TSEN15,RB1,AASDH,RGS12,ELK3,KLHL12,FCGR3B,POLK,IVNS1ABP,THADA,CCDC88A,PKD2L2,C1orf112,NR5A2,LIMCH1,CD244,LRCH1,MTUS2,EML4,BAZ1A,GUF1,IL6ST,LINC00272,FAM151B,CHPT1,KIT,LCP1,AXDND1" MicroRNA hsa-miR-23b:PITA hsa-miR-23b:PITA_TOP PITA 5.95E-14 3.17E-10 2.52E-13 2.31E-12 39 799 "MAP1B,RGS5,MCFD2,APAF1,NCOA1,SLC4A4,FCHO2,DCLK1,CFL2,NRXN1,BOD1L1,RCHY1,POU2F1,CSNK1G3,DNM3,COG3,DMXL1,CEP350,G3BP2,BORA,FNIP1,SUCO,FBXO11,TADA1,SLC12A2,MEGF10,ERBIN,PPARGC1A,ANO4,KMT5A,IGSF8,KLF12,HSP90B1,DCP2,ZMYM2,IRF1,ZBTB41,LHX9,NUAK2" MicroRNA hsa-miR-23a:PITA hsa-miR-23a:PITA_TOP PITA 5.95E-14 3.17E-10 2.52E-13 2.31E-12 39 799 "MAP1B,RGS5,MCFD2,APAF1,NCOA1,SLC4A4,FCHO2,DCLK1,CFL2,NRXN1,BOD1L1,RCHY1,POU2F1,CSNK1G3,DNM3,COG3,DMXL1,CEP350,G3BP2,BORA,FNIP1,SUCO,FBXO11,TADA1,SLC12A2,MEGF10,ERBIN,PPARGC1A,ANO4,KMT5A,IGSF8,KLF12,HSP90B1,DCP2,ZMYM2,IRF1,ZBTB41,LHX9,NUAK2" MicroRNA hsa-miR-518f*:mirSVR_highEffct hsa-miR-518f*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-14 3.45E-10 2.73E-13 2.50E-12 38 762 "RALGAPA1,MAP1B,SEMA6A,APAF1,ARL1,NCOA1,ITGBL1,NRXN1,PKP1,AKAP6,THTPA,SNCAIP,OCIAD1,EGLN3,RASA1,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,ZNF550,PAPPA2,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-526a:mirSVR_highEffct hsa-miR-526a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-14 3.45E-10 2.73E-13 2.50E-12 38 762 "RALGAPA1,MAP1B,SEMA6A,APAF1,ARL1,NCOA1,ITGBL1,NRXN1,PKP1,AKAP6,THTPA,SNCAIP,OCIAD1,EGLN3,RASA1,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,ZNF550,PAPPA2,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-518d-5p:mirSVR_highEffct hsa-miR-518d-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-14 3.45E-10 2.73E-13 2.50E-12 38 762 "RALGAPA1,MAP1B,SEMA6A,APAF1,ARL1,NCOA1,ITGBL1,NRXN1,PKP1,AKAP6,THTPA,SNCAIP,OCIAD1,EGLN3,RASA1,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,ZNF550,PAPPA2,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-520c-5p:mirSVR_highEffct hsa-miR-520c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-14 3.45E-10 2.73E-13 2.50E-12 38 762 "RALGAPA1,MAP1B,SEMA6A,APAF1,ARL1,NCOA1,ITGBL1,NRXN1,PKP1,AKAP6,THTPA,SNCAIP,OCIAD1,EGLN3,RASA1,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,ZNF550,PAPPA2,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-31*:mirSVR_lowEffct hsa-miR-31*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.16E-14 3.81E-10 3.02E-13 2.76E-12 42 925 "PPFIA4,APBB2,STXBP6,KCTD12,BCL2L2,CD84,PCDH9,PIGR,ATAD2B,THAP6,STRN3,RCHY1,LRRTM2,CEP135,DNM3,DMXL1,COCH,GNPDA2,TMEM161B,SLC9C2,RNASEL,LATS2,DCUN1D2,POLK,FOXO1,FBXO11,TADA1,POTEM,YPEL5,MYT1L,PDS5B,ERAP1,KMT5C,DOCK9,GTF3C2,TXK,WDR36,STARD4,IGF1,CCDC190,TTC41P,LOX" MicroRNA hsa-miR-4324:mirSVR_highEffct hsa-miR-4324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.35E-14 3.91E-10 3.09E-13 2.83E-12 35 651 "NDRG2,BLZF1,CACNA1E,CAST,CHAMP1,CD1E,PDE4D,CHD1,WDFY2,ATAD2B,HOMER1,HEATR5A,CEP135,SREK1,OCIAD1,RABGAP1L,RB1,TMEM161B,TXNDC15,LATS2,MPHOSPH9,TOMM40L,MROH9,WDCP,C1orf112,CHFR,RBKS,EML4,RNF17,NPL,TPO,IL25,LAD1,RMST,LMNB1" MicroRNA hsa-miR-544:PITA hsa-miR-544:PITA_TOP PITA 7.48E-14 3.98E-10 3.14E-13 2.88E-12 29 442 "BIRC6,WDR35,FAM193A,ASTN1,NOVA1,SNTG2,CDK17,PRKD1,SREK1,DMXL1,SACS,WDR1,PARPBP,TMEM161B,MBNL2,ETF1,FOXO1,GOLGA2P5,MYT1L,HSPH1,NPAS3,KLHL20,PCDH17,PPARGC1A,PSME4,ATP11A,MTUS2,ADAMTS19,DNAH10" MicroRNA hsa-miR-4288:mirSVR_highEffct hsa-miR-4288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.88E-14 4.19E-10 3.31E-13 3.03E-12 36 690 "RALGAPA1,CUL4A,MSH2,ARL1,KCTD12,WDFY2,JAKMIP1,SNCAIP,VCAN,LRRTM2,FAM169A,COG3,OCIAD1,RASA1,MEMO1,GUSBP3,ETF1,DLEU1,ABCA11P,GORAB,PIBF1,SUCO,FLT1,VEZT,ALKAL2,ZNF605,GABRA2,CMPK2,ANKLE2,LRCH1,PPARGC1A,ADGRL3,IGF1,FAM49A,NPHS2,SPRYD7" MicroRNA hsa-miR-493-5p:TargetScan hsa-miR-493-5p TargetScan 7.99E-14 4.25E-10 3.35E-13 3.07E-12 33 580 "MAP1B,PITPNM2,FBRSL1,MSH2,ARHGAP5,NCOA1,NFKBIA,PDE4D,ATAD2B,AKAP6,GNPTAB,COG3,DNMT3A,MEMO1,SBNO1,MBNL2,ELF1,ETF1,FNIP1,BRMS1L,LIMCH1,MYT1L,GABRB1,KDM5B,NMNAT2,NPAS3,INSM2,ANO4,MSH6,HMGCR,HTR2A,IRF1,KIF2A" MicroRNA hsa-miR-129-3p:PITA hsa-miR-129-3p:PITA_TOP PITA 8.38E-14 4.46E-10 3.52E-13 3.22E-12 22 238 "BIRC6,FAM193A,CACNA1E,MPZL1,RCBTB2,SNX6,HECTD1,RCHY1,GNPTAB,DMXL1,SACS,EGLN3,RB1,MEMO1,LRRN2,NMNAT2,JPH4,HSPH1,KDM3B,ERBIN,FZD10,KLF12" MicroRNA hsa-miR-1200:PITA hsa-miR-1200:PITA_TOP PITA 8.41E-14 4.47E-10 3.52E-13 3.23E-12 26 350 "BCL2L2,ARHGEF7,LDB2,ZNF664,PDE4D,HOMER1,ITSN2,ZFYVE16,PTGS2,DMXL1,CEP350,F11R,LATS2,RNF4,MPHOSPH9,PCGF3,TOMM40L,FBXO11,CHFR,PCDH17,ZNF544,EML4,DOCK9,BAZ1A,SPTSSA,ZBTB41" MicroRNA hsa-miR-759:mirSVR_highEffct hsa-miR-759:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.60E-14 4.57E-10 3.60E-13 3.30E-12 41 889 "MAP1B,HOMEZ,APC,MYBPC1,CBLN3,ODC1,SCARB1,WDFY2,SNX6,HOMER1,AKAP6,GNPTAB,VCAN,DCAF8,MATR3,BIVM,CEP120,PTPRC,TSEN15,SMC6,RGS12,RNASEL,TXNDC15,LATS2,TOMM40L,FMO1,FBXO11,SCYL2,MYO16,RAPGEF6,GJB6,PCDH17,ADGRL3,TFDP1,SLAIN1,STARD4,SPTSSA,RMST,SPRYD7,LMNB1,PABPN1" MicroRNA hsa-miR-432:mirSVR_highEffct hsa-miR-432:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.83E-14 5.23E-10 4.12E-13 3.77E-12 40 852 "MDM4,APAF1,MSH2,KCTD12,NFATC4,PCSK1,THAP6,AKAP6,HEATR5A,SNX17,PARPBP,NR1I3,CLIP4,RNASEL,F7,FCGR3A,PIBF1,POLK,SELP,VEZT,CCDC88A,TMEM183A,KDM3B,SULT1E1,PPARGC1A,ADGRL3,RIPK3,EML4,TFDP1,CRB1,TMPO,MAEL,HEXB,ZNF324B,IL6ST,ANKS1B,LINC00272,NPHS2,ANKDD1B,AXDND1" MicroRNA hsa-miR-4268:mirSVR_highEffct hsa-miR-4268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.92E-14 5.27E-10 4.15E-13 3.80E-12 32 549 "FAM193A,NCOA1,STARD13,ARHGEF7,NOVA1,CDKL2,TSSK4,RGSL1,PDGFRA,PIWIL1,POU2F1,LYSMD3,SNCAIP,SNX17,LGR6,ZNF219,ADGRV1,VEZT,YPEL5,CYP1B1-AS1,NPAS3,DRC1,ADAMTS19,TRPC4,IL25,IGF1,IL6ST,ZMYM2,CHPT1,ANKDD1B,KIR2DL4,RNASE11" MicroRNA hsa-miR-325:mirSVR_highEffct hsa-miR-325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-13 6.07E-10 4.77E-13 4.37E-12 28 417 "BLZF1,ARL1,RAB29,CDKL2,PDE4D,HOMER1,IL20,CSNK1G3,MPHOSPH8,FCRL2,PTPRC,C14orf119,TMEM161B,MBNL2,TRAPPC12,KLHL12,STX2,DLEU1,UTP15,NDUFAF7,ARHGEF40,TADA1,NAAA,ANO4,MAEL,PAPPA2,CHPT1,KCNN2" MicroRNA hsa-miR-887:mirSVR_lowEffct hsa-miR-887:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-13 6.13E-10 4.81E-13 4.40E-12 25 325 "UVSSA,ASCL1,NRL,FCRLB,RFLNA,PDE4D,CHIT1,THAP6,VCAN,SPATA18,PIGG,CEP350,PARPBP,REST,MAEA,GORAB,TNFRSF19,RELL1,TMEM183A,ZNF544,ADAMTS19,HPCAL1,TADA2B,CCDC169,AXDND1" MicroRNA hsa-miR-181c*:mirSVR_lowEffct hsa-miR-181c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-13 6.13E-10 4.81E-13 4.40E-12 30 483 "SFTA3,ATP7B,ZMYM5,PDE4D,SMIM14,DNM3,KIAA0040,UBXN2A,SREK1,CEP350,TBC1D4,OCIAD1,G3BP2,PARPBP,LAP3,ETF1,MROH9,STAB2,RUBCNL,SLC8A1,SLC12A2,GABRA2,IQGAP2,GJA3,MAST4,ADGRA3,C5orf56,TMPO,MAEL,GPN1" MicroRNA hsa-miR-509-3-5p:mirSVR_highEffct hsa-miR-509-3-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-13 6.25E-10 4.90E-13 4.49E-12 42 939 "RALGAPA1,MDM4,CDKL4,WDR19,ARHGEF7,ADGRD1,FCHO2,UHMK1,NFXL1,CDK17,PDGFRA,TSTD1,AKAP6,SACS,G3BP2,RAN,POLR1D,LATS2,F7,TOMM40L,RELL1,PEAR1,SELP,FBXO11,G2E3,ZNF446,N4BP2,YPEL5,LIMCH1,ATP8A2,LILRB1,ADGRA3,TDG,TENT2,ZFHX2,IL6ST,ZMYM2,SDR39U1,LHX9,FIP1L1,FAM71C,PABPN1" MicroRNA hsa-miR-620:mirSVR_highEffct hsa-miR-620:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-13 6.27E-10 4.91E-13 4.50E-12 43 981 "ANKRD34B,APAF1,ATP12A,STARD13,PNP,CDK17,RCBTB2,VIT,STRN3,LYSMD3,VCAN,CEP135,PIGG,G3BP2,ATG10,AASDH,MEMO1,POLR1D,RNF4,MBNL2,MPHOSPH9,CWC27,LRRN2,NUBPL,SLC22A4,MRPS14,LIMCH1,MYO16,GABRA2,TMEM183A,CMPK2,SRP72,PPARGC1A,STRN,GPR12,RNF212,RXFP2,VRK2,STARD4,ZMYM2,LINC00272,RNASE11,AXDND1" MicroRNA hsa-miR-608:mirSVR_highEffct hsa-miR-608:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-13 6.93E-10 5.42E-13 4.96E-12 35 664 "MAP1B,ASCL1,NCOA1,CARMIL3,CD84,LDB2,SLC5A8,EPN1,TAPT1,THTPA,POU2F1,EIF2AK2,BIVM,SPATA18,RNF4,KIRREL1,GP6,NDUFAF7,TACC3,SELP,STAB2,GOLGA2P5,PKD2L2,IQGAP2,ERAP1,ZNF544,NCSTN,FCRLA,RIMBP2,CCDC169,LHX9,RNASE11,LCP1,LINC00442,SPRYD7" MicroRNA hsa-miR-129-1-3p:TargetScan hsa-miR-129-1-3p TargetScan 1.33E-13 7.08E-10 5.53E-13 5.06E-12 26 357 "BIRC6,NLN,MCFD2,NCOA1,BCL2L2,CACNA1E,MPZL1,RCBTB2,HECTD1,RCHY1,GNPTAB,DMXL1,SACS,EGLN3,MEMO1,EFNA5,BORA,NBEA,NMNAT2,JPH4,HSPH1,KDM3B,KLHL20,CNTN2,FZD10,KLF12" MicroRNA hsa-miR-129-2-3p:TargetScan hsa-miR-129-2-3p TargetScan 1.33E-13 7.08E-10 5.53E-13 5.06E-12 26 357 "BIRC6,NLN,MCFD2,NCOA1,BCL2L2,CACNA1E,MPZL1,RCBTB2,HECTD1,RCHY1,GNPTAB,DMXL1,SACS,EGLN3,MEMO1,EFNA5,BORA,NBEA,NMNAT2,JPH4,HSPH1,KDM3B,KLHL20,CNTN2,FZD10,KLF12" MicroRNA hsa-miR-19b:PITA hsa-miR-19b:PITA_TOP PITA 1.34E-13 7.11E-10 5.54E-13 5.08E-12 37 741 "MAP1B,PITPNM2,ARHGAP5,CAST,CFL2,WDFY2,PITX1,HOMER1,CLOCK,LRRTM2,DCAF8,SNX17,CEP350,G3BP2,WDR1,RASA1,MEMO1,MBNL2,ELK3,MPHOSPH9,CLIP1,SDC1,NBEA,IVNS1ABP,CCDC88A,MYT1L,FAM114A1,KLHL20,ATP11A,GRSF1,RIMBP2,SLAIN1,TENT2,DCP2,IGF1,SPTSSA,KIT" MicroRNA hsa-miR-19a:PITA hsa-miR-19a:PITA_TOP PITA 1.34E-13 7.11E-10 5.54E-13 5.08E-12 37 741 "MAP1B,PITPNM2,ARHGAP5,CAST,CFL2,WDFY2,PITX1,HOMER1,CLOCK,LRRTM2,DCAF8,SNX17,CEP350,G3BP2,WDR1,RASA1,MEMO1,MBNL2,ELK3,MPHOSPH9,CLIP1,SDC1,NBEA,IVNS1ABP,CCDC88A,MYT1L,FAM114A1,KLHL20,ATP11A,GRSF1,RIMBP2,SLAIN1,TENT2,DCP2,IGF1,SPTSSA,KIT" MicroRNA hsa-miR-920:mirSVR_highEffct hsa-miR-920:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-13 7.80E-10 6.08E-13 5.56E-12 32 557 "MATN3,CUL4A,B4GALT3,BCL2L2,FCGR2C,PDE4D,ZNF595,ITGBL1,COPA,DNMT3A,RASA1,RGS4,RNASEL,DHRS2,FCAMR,PCGF3,FCAR,FCGR2B,PEAR1,DDX51,PAICS,PKD2L2,CGREF1,WDCP,NMNAT2,NCSTN,ACTR6,TPTE2,LHX9,FAM151B,FIP1L1,IFT88" MicroRNA hsa-miR-9:PITA hsa-miR-9:PITA_TOP PITA 1.55E-13 8.22E-10 6.40E-13 5.86E-12 33 594 "ABL2,MAP1B,CUL4A,PITPNM2,NCOA1,STARD13,KCTD12,CACNA1E,CLOCK,NCOR2,CEP350,SACS,MTX3,IPO4,MAEA,ETF1,FNIP1,RELL1,FOXG1,SLC8A1,CCDC88A,NR5A2,NFASC,ERBIN,PCDH17,ATP11A,DOCK9,XPO4,GRSF1,TGFBI,KLF12,SPTSSA,ZBTB41" MicroRNA hsa-miR-3165:mirSVR_lowEffct hsa-miR-3165:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-13 8.43E-10 6.56E-13 6.01E-12 48 1208 "MATN3,ZNF784,NOP14,ASTN1,KCTD12,CARMIL3,LINC02347,FCHO2,CHAMP1,CFL2,PFKFB2,CCDC122,ZNF595,FAM163A,RCHY1,GNPTAB,C12orf65,NOP9,F11R,RABGAP1L,NR1I3,TMEM161B,DTD2,SETDB2,ARSK,PCGF3,FCAR,SDC1,FBXO11,NUBPL,PAICS,ZNF446,SLC30A6,NR5A2,MRPS27,CMPK2,NFASC,ZNF544,KMT5A,KHNYN,COP1,LINC01551,MAEL,CENPH,PLB1,LHX9,TTC7A,AXDND1" MicroRNA hsa-miR-206:TargetScan hsa-miR-206 TargetScan 1.64E-13 8.74E-10 6.79E-13 6.22E-12 34 632 "RALGAPA1,ABL2,ANKRD34B,NCOA1,BCL2L2,PNP,MPZL1,PFKFB2,GNPTAB,CLOCK,BRI3BP,KIAA0040,MATR3,G3BP2,RABGAP1L,DNMT3A,RASA1,ELF1,G2E3,NBEA,POTEM,GAK,NPAS3,LRCH1,PCDH17,EML4,HSP90B1,HMGCR,GUF1,DCP2,IGF1,IL6ST,KIF2A,LETM1" MicroRNA hsa-miR-1-3p:TargetScan hsa-miR-1-3p TargetScan 1.64E-13 8.74E-10 6.79E-13 6.22E-12 34 632 "RALGAPA1,ABL2,ANKRD34B,NCOA1,BCL2L2,PNP,MPZL1,PFKFB2,GNPTAB,CLOCK,BRI3BP,KIAA0040,MATR3,G3BP2,RABGAP1L,DNMT3A,RASA1,ELF1,G2E3,NBEA,POTEM,GAK,NPAS3,LRCH1,PCDH17,EML4,HSP90B1,HMGCR,GUF1,DCP2,IGF1,IL6ST,KIF2A,LETM1" MicroRNA hsa-miR-196a*:mirSVR_highEffct hsa-miR-196a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.70E-13 9.06E-10 7.04E-13 6.44E-12 41 908 "RALGAPA1,NDRG2,ADD1,COG6,NYNRIN,APC,KCTD12,ADGRD1,DCLK1,CFL2,VIT,NRXN1,HECTD1,AKAP6,PREPL,SREK1,RABGAP1L,DHFR,WDR1,DNMT3A,RGS12,SNORA49,ARSK,PCGF3,PCBD2,FNIP1,CCDC88A,SLC15A4,GABRB1,KDM5B,NPAS3,ZBTB37,BRD8,GPR12,RNF17,LTB4R2,GUF1,KCNT2,TMEM178A,KIT,SKA3" MicroRNA hsa-miR-381:PITA hsa-miR-381:PITA_TOP PITA 1.72E-13 9.12E-10 7.07E-13 6.47E-12 31 525 "BIRC6,NLN,ATP2B4,CARMIL3,NFKBIA,FCHO2,LDB2,NRXN1,CSNK1G3,LRRTM2,BIVM,TBC1D4,TMEM161B,NTN4,MBNL2,MPHOSPH9,ETF1,PCGF3,ELOVL7,FNIP1,NBEA,NR5A2,MEGF10,PDS5B,KDM5B,RAPGEF6,PCDH17,ADGRA3,ANO4,KLF12,SPTSSA" MicroRNA hsa-miR-300:PITA hsa-miR-300:PITA_TOP PITA 1.72E-13 9.12E-10 7.07E-13 6.47E-12 31 525 "BIRC6,NLN,ATP2B4,CARMIL3,NFKBIA,FCHO2,LDB2,NRXN1,CSNK1G3,LRRTM2,BIVM,TBC1D4,TMEM161B,NTN4,MBNL2,MPHOSPH9,ETF1,PCGF3,ELOVL7,FNIP1,NBEA,NR5A2,MEGF10,PDS5B,KDM5B,RAPGEF6,PCDH17,ADGRA3,ANO4,KLF12,SPTSSA" MicroRNA hsa-miR-582-5p:TargetScan hsa-miR-582-5p TargetScan 1.73E-13 9.20E-10 7.13E-13 6.53E-12 29 457 "APC,NOVA1,PDE4D,PFKFB2,COG3,RASA1,ELF1,MPHOSPH9,SAP18,MAEA,FGF9,FOXG1,FOXO1,FBXO11,C1orf112,NR5A2,MYT1L,HSPH1,NPAS3,NFASC,ADAM17,PPIP5K2,ACSL6,MSH6,KLF12,HSP90B1,HMGCR,GUF1,DCP2" MicroRNA hsa-miR-30c-1*:mirSVR_highEffct hsa-miR-30c-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.77E-13 9.42E-10 7.29E-13 6.67E-12 47 1167 "NDRG2,SLAMF6,WDR35,ATP7B,ARHGEF7,BTF3,PNP,MPZL1,LDB2,PCK2,CHIT1,ZNF595,WDFY2,HOMER1,AKAP6,COPA,PM20D1,TTC37,DNM3,DCAF8,PSME1,CEP120,PTPRH,NR1I3,FAM129A,AASDH,CLIP4,MBNL2,KIRREL1,ARSK,DLEU1,RELL1,STAB2,RUBCNL,SLC8A1,PKD2L2,WDCP,PDS5B,ERAP1,KLHL20,TMED2,CRB1,TECRL,DCP2,IRF1,RMST,LMNB1" MicroRNA hsa-miR-663b:mirSVR_lowEffct hsa-miR-663b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-13 9.79E-10 7.57E-13 6.93E-12 48 1213 "IL17D,NDRG2,ADD1,ADORA1,DHX37,FAM193A,KCTD12,FGFRL1,ARHGEF7,SLC5A6,ADGRD1,MPZL1,ODC1,RGSL1,CFL2,PFKFB2,PIGR,PTPRVP,POU2F1,FCRL5,SLC35F6,TSEN15,OGFOD2,RNF4,ELK3,TCTN2,STX2,EFS,ARSK,FCAR,SPON2,FGF9,SDC1,FTLP10,GOLGA2P5,ARHGEF40,CCDC88A,TMEM132D,DHRS4,TMED2,NCSTN,ATP6V0A2,ARHGAP30,C12orf73,MFSD2B,LCP1,NUAK2,TTC7A" MicroRNA hsa-miR-628-3p:mirSVR_highEffct hsa-miR-628-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-13 1.00E-09 7.74E-13 7.09E-12 39 829 "BLZF1,ZNF542P,FCHO2,CD1D,PCDH9,PDE4D,PDGFRA,HOMER1,TAPT1,PM20D1,LACC1,MPHOSPH8,SREK1,PTGS2,OCIAD1,DNMT3A,SMC6,PACRGL,ELF1,ABCA11P,SH3YL1,GORAB,POLK,VEZT,SLC8A1,TADA1,C1orf112,HSPH1,OXGR1,NPAS3,ZNF544,YIPF7,TEP1,ZNF721,ADAMTS19,ZNF876P,STARD4,KCNN2,LOX" MicroRNA hsa-miR-505:mirSVR_highEffct hsa-miR-505:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.89E-13 1.01E-09 7.77E-13 7.12E-12 43 995 "ANKRD34B,WDR35,WDR19,CENPBD1P1,NOVA1,CDKL2,PAH,ZMYM5,PDGFRA,NUP37,UGT2B28,AKAP6,TAPT1,VCAN,FCRL2,DHFR,B3GLCT,RNASEL,ELK3,FAM172A,MAEA,NDUFAF7,FGF9,PIBF1,ALKAL2,SLC15A4,MYT1L,PDS5B,GJB6,SULT1E1,PPARGC1A,TFDP1,CRB1,LINC01551,AP4S1,BAZ1A,TMPO,ATP6V0A2,KCNT2,ZNF84,KIT,AXDND1,SKA3" MicroRNA hsa-miR-921:mirSVR_highEffct hsa-miR-921:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.92E-13 1.02E-09 7.87E-13 7.21E-12 35 673 "NDRG2,KIAA1211,CUL4A,EP400,WDR19,MPZL1,FCGR2C,RCBTB2,JAKMIP1,HECTD1,HOMER1,UBXN2A,FCRL5,SPATA18,SREK1,NUDT12,MBNL2,UGT2A3,KLHL12,ADGRV1,FCAR,FOXO1,VEZT,PAICS,CCDC88A,GABRA2,HSPH1,NEDD1,ADGRL3,ZBTB49,AP4S1,TMPO,TMEM174,PGAM5,KCNN2" MicroRNA hsa-miR-144-3p:TargetScan hsa-miR-144-3p TargetScan 2.00E-13 1.06E-09 8.19E-13 7.50E-12 37 751 "MAP1B,MDM4,NLN,PPFIA4,APC,KCTD12,NOVA1,PDE4D,CFL2,PGGT1B,ATAD2B,POU2F1,LYSMD3,ITSN2,LRRTM2,CEP135,PTGS2,MTX3,DNMT3A,RASA1,EFNA5,MBNL2,FOXG1,FOXO1,CCDC88A,MRPS14,NR5A2,LIMCH1,PDS5B,KDM3B,GRSF1,KLF12,HMGCR,PAPPA2,KIF2A,KIT,PABPN1" MicroRNA hsa-miR-1914*:mirSVR_lowEffct hsa-miR-1914*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-13 1.10E-09 8.48E-13 7.76E-12 54 1495 "NYNRIN,WDR19,BCL2L2,MORN2,FCGR2C,CDK18,SMIM14,CLOCK,NCOR2,ITSN2,KIAA0040,ZNF586,SLC35F6,NR1I3,RGS12,GUSBP3,KIRREL1,CLIP1,ARL6IP4,SUCO,SELP,FMO1,DDX51,ALKAL2,NLRP2,SLC8A1,ARHGEF40,TADA1,SLC12A2,CGREF1,YPEL5,KDM5B,TMEM183A,IQGAP2,NFASC,TCF7,EML4,DOCK9,FCRLA,SLC7A8,ZBTB49,LINC01551,RIMBP2,ATP6V0A2,IGSF8,TENT2,ZFHX2,CCDC169,PLB1,ANKS1B,KIF3C,LINC01913,LINC00442,PABPN1" MicroRNA hsa-miR-563:mirSVR_lowEffct hsa-miR-563:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-13 1.16E-09 8.95E-13 8.20E-12 39 833 "RALGAPA1,MCC,STXBP6,SLC4A4,NOVA1,CHAMP1,SLC5A8,PCDH9,RGSL1,PDGFRA,CENPC,ADGRF3,LTB4R,HECTD1,AKAP6,VCAN,MATR3,COCH,PTPRC,PARPBP,ADGRV1,N4BP2L2,TNFRSF19,SUPT20H,GOLGA2P5,PLEKHA6,UFM1,MEGF10,ATP8A2,ZBTB37,UGT2A1,ADGRL3,ADGRA3,TFDP1,CRB1,ZNF140,ZMYM2,LHX9,KCNN2" MicroRNA hsa-miR-208a:mirSVR_lowEffct hsa-miR-208a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.45E-13 1.30E-09 1.00E-12 9.16E-12 39 836 "RALGAPA1,MIPEP,APC,STXBP6,ASCL1,ATP1A2,NOVA1,MPZL1,MORN2,CDK17,HECTD1,ZFYVE16,PTPRC,PPP2R3C,B3GLCT,POLR1D,RNASEL,GRTP1,TCTN2,ETF1,USP44,NDUFAF7,FNIP1,VEZT,SLC30A6,SCYL2,SLC22A5,GABRA2,SRP72,GCKR,BAZ1A,TRPC4,TECRL,ZNF470,C12orf73,ANKS1B,AMTN,RNASE11,LIG4" MicroRNA hsa-miR-3151:mirSVR_lowEffct hsa-miR-3151:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.66E-13 1.42E-09 1.09E-12 9.96E-12 61 1848 "ADD1,NYNRIN,SEMA6A,PITPNM2,SNX24,ASTN1,CD84,ARHGEF7,AP1G2,ADGRD1,DAOA,TAF1B,CAST,SCARB1,CDK7,CDK18,WDFY2,POLN,FAM163A,FCRL5,PIGG,RABGAP1L,WDR1,RNF31,IPO4,RNASEL,LATS2,MARVELD2,DHRS2,MAEA,PCGF3,TMEM129,UTP15,TOMM40L,NDUFAF7,SPON2,FGFR3,HSD17B7,SGCG,SH3BP2,SLC8A1,YPEL5,EFR3B,MYT1L,PDS5B,KDM5B,MRPS27,INSM2,TMED2,RIPK3,CRB1,ZBTB49,FZD10,TXK,KCNT2,LINC00272,PGAM5,CHPT1,KIT,RILPL2,TTC7A" MicroRNA hsa-miR-655-3p:TargetScan hsa-miR-655-3p TargetScan 2.68E-13 1.42E-09 1.09E-12 1.00E-11 33 606 "ADD1,APBB2,APC,ASCL1,NCOA1,CCNB1IP1,BCL2L2,GAS2L3,DCLK1,CDK17,PDGFRA,NUP37,POU2F1,LYSMD3,CEP135,PRKD1,MATR3,COG3,RABGAP1L,MEMO1,EFNA5,SBNO1,ELK3,ETF1,FNIP1,FOXO1,N4BP2,HSPH1,DOCK9,HMGCR,ANKS1B,RILPL2,PABPN1" MicroRNA hsa-miR-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.69E-13 1.43E-09 1.10E-12 1.01E-11 41 921 "MSH2,ATP2B4,PNP,CAD,CAST,AMDHD1,CHAMP1,UHMK1,DHRS1,SMIM14,SNX6,BRI3BP,TTC37,MATR3,PSME1,SREK1,KLHL3,F11R,G3BP2,RABGAP1L,GNPDA2,ARGLU1,SLC8A1,NR5A2,UGGT2,CPSF3,GAK,MRPS27,MAST4,EML4,SNRNP35,NT5C1B,MSH6,HSP90B1,IGF1,SDR39U1,KIF2A,NT5C1B-RDH14,LCP1,LETM1,LMNB1" MicroRNA hsa-miR-4296:mirSVR_lowEffct hsa-miR-4296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.80E-13 1.49E-09 1.14E-12 1.04E-11 51 1365 "RALGAPA1,ADORA1,WDR35,UVSSA,FAM193A,ATP4B,FCRL3,NRL,MPZL1,RILPL1,CD1E,PCK2,CDK18,RGSL1,CCDC122,ADGRF3,THAP6,ZNF586,IFT172,FBXL5,ATG10,OGFOD2,LATS2,DLEU1,PCGF3,PCBD2,FLT1,RASA3,HSPH1,CMPK2,PPIP5K2,GOLGA3,C5orf56,RIPK3,ARHGEF28,STON1,NCSTN,NT5C1B,RASSF6,RIMBP2,IGSF8,VRK2,NSD2,KCNT2,ZFHX2,ZNF140,LHX9,CHPT1,EP400P1,RILPL2,LTA4H" MicroRNA hsa-miR-1245:mirSVR_highEffct hsa-miR-1245:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-13 1.49E-09 1.14E-12 1.05E-11 33 607 "KIAA1211,BLZF1,KCTD12,RAB29,PCSK1,CDK17,RCBTB2,WDFY2,HEATR5A,VCAN,PIGG,COCH,RABGAP1L,RASA1,RB1,ADGRV1,FNIP1,SUCO,FLT3,ZCCHC8,BRMS1L,SCYL2,PSME4,TBC1D1,MTUS2,ANO4,TMPO,TPO,HMGCR,RXFP2,HTR2A,ZNF10,CHPT1" MicroRNA hsa-miR-623:mirSVR_highEffct hsa-miR-623:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.87E-13 1.52E-09 1.17E-12 1.07E-11 36 721 "MDM4,NDRG2,DDX55,AACS,LINC02347,NOVA1,AMDHD1,FCHO2,CD1E,DCLK1,RGSL1,GLT1D1,WDFY2,CRHBP,SNCAIP,RASA1,MARVELD2,ZNF671,ARSK,TMEM156,TOMM40L,NDUFAF7,GORAB,SLC12A2,WDCP,CHFR,KLHL20,ADGRA3,CRB1,HEXB,HMGCR,GUF1,KCNT2,IL6ST,LINC00272,RMST" MicroRNA hsa-miR-93:PITA hsa-miR-93:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-106b:PITA hsa-miR-106b:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-106a:PITA hsa-miR-106a:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-20b:PITA hsa-miR-20b:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-20a:PITA hsa-miR-20a:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-17:PITA hsa-miR-17:PITA_TOP PITA 2.87E-13 1.53E-09 1.17E-12 1.07E-11 38 800 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-553:mirSVR_highEffct hsa-miR-553:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-13 1.56E-09 1.19E-12 1.09E-11 27 401 "MCFD2,FBRSL1,SLC4A4,LINC02347,CDKL2,PDE4D,GPR180,ADGRF3,HECTD1,CEP135,CEP120,ARGLU1,AASDH,GRTP1,DNAJC27,CLIP1,FNIP1,VEZT,TADA1,GJB6,IKBIP,PPARGC1A,PPIP5K2,GPR12,NSD2,FAM49A,FIP1L1" MicroRNA hsa-miR-208b:mirSVR_lowEffct hsa-miR-208b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.94E-13 1.56E-09 1.19E-12 1.09E-11 39 841 "RALGAPA1,MIPEP,APC,STXBP6,ASCL1,ATP1A2,NOVA1,MPZL1,MORN2,CDK17,HECTD1,ZFYVE16,PTPRC,PPP2R3C,B3GLCT,POLR1D,GRTP1,TCTN2,ETF1,USP44,NDUFAF7,FNIP1,VEZT,SLC30A6,SCYL2,THADA,SLC22A5,MEGF10,SRP72,GCKR,BAZ1A,TRPC4,TECRL,ZNF470,C12orf73,ANKS1B,AMTN,RNASE11,LIG4" MicroRNA hsa-miR-519d:PITA hsa-miR-519d:PITA_TOP PITA 3.10E-13 1.65E-09 1.25E-12 1.15E-11 38 802 "ABL2,ULK1,APBB2,ARL1,SLC4A4,BCL2L2,ARHGEF7,FCHO2,FAM177A1,PDGFRA,CFL2,LYSMD3,CLOCK,DCAF8,FBXL5,CEP120,SACS,GNPDA2,EGLN3,RB1,CLIP4,NTN4,ELK3,ETF1,DNAJC27,RELL1,SUCO,NBEA,BRMS1L,MYT1L,NPAS3,ERBIN,KLHL20,RIMBP2,KLF12,UBC,IRF1,ZBTB41" MicroRNA hsa-miR-200c*:mirSVR_highEffct hsa-miR-200c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.10E-13 1.65E-09 1.25E-12 1.15E-11 31 537 "MAP1B,ATP1A2,PDE4D,THAP6,SYCP3,LYSMD3,CRHBP,VCAN,DMXL1,DHFR,GUSBP3,SNORA49,ARSK,CCDC38,UTP15,NUBPL,C1orf112,MYT1L,NAAA,LRCH1,IKBIP,PCDH17,COX7B2,RIPK3,DOCK9,CRB1,TMPO,C12orf73,LHX9,KCNN2,KIF2A" MicroRNA hsa-miR-186-5p:TargetScan hsa-miR-186-5p TargetScan 3.18E-13 1.69E-09 1.29E-12 1.18E-11 35 685 "MCFD2,APBB2,ARHGAP5,ATP1A2,ATP2B4,PPP1R12B,BTF3,NRL,CAST,RILPL1,PCSK1,PDE4D,PGGT1B,NUP37,DHX9,DTD2,EIF2D,SBNO1,ELF1,DNAJC27,G2E3,NR5A2,MYT1L,PDS5B,ATP8A2,PCDH17,GJA3,PPIP5K2,GPR12,GTF3C2,KLF12,PAPPA2,IGF1,CAB39L,LOX" MicroRNA hsa-miR-515-3p:mirSVR_lowEffct hsa-miR-515-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.25E-13 1.73E-09 1.31E-12 1.20E-11 50 1324 "SMIM15,KIAA1211,ATP6V1G3,APC,ARL1,RAB29,SCARB1,WDR66,C12orf65,DNM3,PSME1,COG3,OCIAD1,GNPDA2,ATG10,OGFOD2,EFNA5,ETF1,GMPR2,TRAPPC13,NDUFAF7,LRRN2,TNFRSF19,PEAR1,FOXO1,SUPT20H,NBEA,STPG4,TADA1,SLC22A5,GABRA2,PDS5B,NMNAT2,JPH4,ERAP1,LRCH1,GJA3,STON1,TFDP1,CRB1,ARHGAP30,TECRL,SLAIN1,IL25,C12orf73,IL6ST,SDR39U1,ZBED3-AS1,KIT,LMNB1" MicroRNA hsa-miR-190a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-13 1.84E-09 1.40E-12 1.28E-11 34 649 "DDX55,ATP2B4,MYBPC1,UHMK1,FAM177A1,CFL2,NUP37,POU2F1,BRI3BP,G3BP2,SLC35F6,TMEM161B,REST,MBNL2,EIF2B1,ARSK,CCDC38,NDUFAF7,BRMS1L,PLEKHA6,SLC8A1,SLC12A2,SRP72,LILRB1,PPARGC1A,STRN,PPIP5K2,UBE2K,TECRL,NLRP8,IGF1,IL6ST,ZMYM2,LMNB1" MicroRNA hsa-miR-331-3p:mirSVR_highEffct hsa-miR-331-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.50E-13 1.86E-09 1.41E-12 1.29E-11 23 283 "NLN,PSME1,TINF2,RNF219,ABCA11P,ELOVL7,FCGR3A,FCGR3B,NBEA,TMEM132D,CYP1B1-AS1,GC,LRCH1,IKBIP,KHNYN,TDG,TEP1,ZNF721,ZNF550,CCDC169,PLB1,SLAMF9,PABPN1" MicroRNA hsa-miR-323-5p:mirSVR_lowEffct hsa-miR-323-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-13 1.98E-09 1.50E-12 1.37E-11 46 1147 "MCC,MDM4,ATP2B4,PROZ,CCNA1,CACNA1E,CDK17,VIT,ZNF595,SNX6,LTB4R,PTPRVP,TAPT1,POLE,TOGARAM2,POU2F1,VCAN,SPATA18,PTPRC,IPO4,MAEA,FCAR,GORAB,STAB2,GFM2,C1orf112,SF3B6,CYP1B1-AS1,MYO16,LPIN1,BRD8,MAST4,UGT2A1,INSM2,CNTN2,TCF7,FCRLA,SLC7A8,AP4S1,TPO,ADAMTS19,TECRL,TXK,YTHDC2,PLB1,SLAMF9" MicroRNA hsa-miR-133a:mirSVR_lowEffct hsa-miR-133a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-13 1.98E-09 1.50E-12 1.37E-11 46 1147 "IL17D,MCFD2,WDR19,PPP1R12B,BCL2L2,NFKBIA,RAB29,CDKL2,SYT2,ANAPC4,PRKD1,DMXL1,COCH,RASA1,SMC6,SLC9C2,GRTP1,DHRS2,TMEM129,FCAR,FCGR3A,FCGR3B,SDC1,FOXG1,SELP,MROH9,RASA3,IQGAP2,LRCH1,IKBIP,GPR12,DOCK9,XPO4,SLC7A8,LINC01551,RASSF6,ADAMTS19,TENT2,NSD2,IL6ST,SPTSSA,ANKS1B,KCNJ9,FIP1L1,KIR2DS4,LINC01913" MicroRNA hsa-miR-133b:mirSVR_lowEffct hsa-miR-133b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-13 1.98E-09 1.50E-12 1.37E-11 46 1147 "IL17D,MCFD2,WDR19,PPP1R12B,BCL2L2,NFKBIA,RAB29,CDKL2,SYT2,ANAPC4,PRKD1,DMXL1,COCH,RASA1,SMC6,SLC9C2,GRTP1,DHRS2,TMEM129,FCAR,FCGR3A,FCGR3B,SDC1,FOXG1,SELP,MROH9,RASA3,IQGAP2,LRCH1,IKBIP,GPR12,DOCK9,XPO4,SLC7A8,LINC01551,RASSF6,ADAMTS19,TENT2,NSD2,IL6ST,SPTSSA,ANKS1B,KCNJ9,FIP1L1,KIR2DS4,LINC01913" MicroRNA hsa-miR-148b-3p:TargetScan hsa-miR-148b-3p TargetScan 3.78E-13 2.01E-09 1.52E-12 1.39E-11 32 577 "ABL2,MAP1B,MDM4,PITPNM2,NCOA1,ATP2B4,BCL2L2,NOVA1,CAST,PDE4D,CFL2,CHD1,GPR180,HOMER1,LYSMD3,CLOCK,ITSN2,PIGG,DMXL1,RNF219,SBNO1,FBXO11,LRCH1,PPARGC1A,ATP11A,ADAM17,ADAMTS19,HSP90B1,DCP2,IGF1,IL6ST,KIT" MicroRNA hsa-miR-148a-3p:TargetScan hsa-miR-148a-3p TargetScan 3.78E-13 2.01E-09 1.52E-12 1.39E-11 32 577 "ABL2,MAP1B,MDM4,PITPNM2,NCOA1,ATP2B4,BCL2L2,NOVA1,CAST,PDE4D,CFL2,CHD1,GPR180,HOMER1,LYSMD3,CLOCK,ITSN2,PIGG,DMXL1,RNF219,SBNO1,FBXO11,LRCH1,PPARGC1A,ATP11A,ADAM17,ADAMTS19,HSP90B1,DCP2,IGF1,IL6ST,KIT" MicroRNA hsa-miR-152-3p:TargetScan hsa-miR-152-3p TargetScan 3.78E-13 2.01E-09 1.52E-12 1.39E-11 32 577 "ABL2,MAP1B,MDM4,PITPNM2,NCOA1,ATP2B4,BCL2L2,NOVA1,CAST,PDE4D,CFL2,CHD1,GPR180,HOMER1,LYSMD3,CLOCK,ITSN2,PIGG,DMXL1,RNF219,SBNO1,FBXO11,LRCH1,PPARGC1A,ATP11A,ADAM17,ADAMTS19,HSP90B1,DCP2,IGF1,IL6ST,KIT" MicroRNA hsa-miR-518a-5p:PITA hsa-miR-518a-5p:PITA_TOP PITA 3.80E-13 2.02E-09 1.52E-12 1.39E-11 30 506 "MCC,ULK1,BTF3,NOVA1,CACNA1E,FCHO2,WDFY2,ATAD2B,PITX1,TAPT1,IL20,PRKD1,FBXL5,CEP350,TBC1D4,MEMO1,MBNL2,TBC1D19,ETF1,PCGF3,TOMM40L,NBEA,SLC30A6,IVNS1ABP,SLC8A1,NPAS3,TMED2,ATP11A,KIT,PABPN1" MicroRNA hsa-miR-527:PITA hsa-miR-527:PITA_TOP PITA 3.80E-13 2.02E-09 1.52E-12 1.39E-11 30 506 "MCC,ULK1,BTF3,NOVA1,CACNA1E,FCHO2,WDFY2,ATAD2B,PITX1,TAPT1,IL20,PRKD1,FBXL5,CEP350,TBC1D4,MEMO1,MBNL2,TBC1D19,ETF1,PCGF3,TOMM40L,NBEA,SLC30A6,IVNS1ABP,SLC8A1,NPAS3,TMED2,ATP11A,KIT,PABPN1" MicroRNA hsa-miR-934:mirSVR_highEffct hsa-miR-934:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.96E-13 2.11E-09 1.58E-12 1.45E-11 32 578 "ATP4B,NOVA1,CAST,SCFD2,PDE4D,PDGFRA,CCDC122,ATAD2B,TOGARAM2,LYSMD3,PREPL,SNCAIP,VCAN,F11R,PPP2R3C,NR1H4,POLR1D,TMEM156,IRF9,BRMS1L,UFM1,ZNF605,GABRA2,GJB6,ANKLE2,IKBIP,ACTR6,HEXB,PLB1,TDRD3,ANKDD1B,FIP1L1" MicroRNA hsa-miR-200a*:mirSVR_highEffct hsa-miR-200a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.24E-13 2.25E-09 1.69E-12 1.55E-11 39 851 "FAM193A,NOVA1,UHMK1,THAP6,RCHY1,PREPL,EIF2AK2,DDX59,ZFYVE16,NUDT12,NR1H4,ATG10,UGT2A3,STX2,DNAJC27,ABCA11P,CCDC38,RELL1,TADA1,C1orf112,SLC22A4,LIMCH1,GABRA2,PDS5B,OXGR1,NPAS3,CMPK2,RBKS,AURKC,INSM2,C5orf56,TMPO,ATP6V0A2,WDR36,NSD2,KCNT2,ANKS1B,SDR39U1,LOX" MicroRNA hsa-miR-223:PITA hsa-miR-223:PITA_TOP PITA 4.25E-13 2.26E-09 1.70E-12 1.55E-11 21 231 "MAP1B,APC,NCOA1,CDK17,PDE4D,HOMER1,SREK1,KLHL3,SACS,RNF4,MBNL2,FOXO1,BRMS1L,SLC8A1,PKD2L2,PDS5B,SRP54,NFASC,DOCK9,HSP90B1,IL6ST" MicroRNA hsa-miR-4322:mirSVR_lowEffct hsa-miR-4322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.36E-13 2.32E-09 1.74E-12 1.59E-11 53 1476 "RALGAPA1,ADORA1,WDR35,UVSSA,FAM193A,ATP1A2,ATP4B,FCRL3,NRL,MPZL1,RILPL1,CD1E,PCK2,CDK18,ADGRF3,THAP6,ZNF586,IFT172,FBXL5,ATG10,OGFOD2,LATS2,DLEU1,PCGF3,PCBD2,FLT1,RASA3,ZNF446,HSPH1,CMPK2,PPIP5K2,GOLGA3,C5orf56,RIPK3,ARHGEF28,STON1,NCSTN,NT5C1B,RASSF6,RIMBP2,IGSF8,VRK2,NSD2,KCNT2,ZFHX2,ZNF140,PGAM5,LHX9,CHPT1,EP400P1,RILPL2,LINC00442,LTA4H" MicroRNA hsa-miR-338-5p:PITA hsa-miR-338-5p:PITA_TOP PITA 4.72E-13 2.51E-09 1.88E-12 1.72E-11 37 773 "MAP1B,SEMA6A,ULK1,CUL4A,APBB2,MSH2,ARHGAP5,FAM193A,SLC4A4,LDB2,PCDH9,CDK17,CHD1,HOMER1,DNM3,ZFYVE16,NUDT12,MTX3,RNF219,RGS4,MBNL2,ARSK,CLIP1,FOXO1,FBXO11,NBEA,NR5A2,MYT1L,KDM5B,PCDH17,PPARGC1A,STRN,ATP11A,ACSL6,DOCK9,GTF3C2,ZNF470" MicroRNA hsa-miR-1269:mirSVR_highEffct hsa-miR-1269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.79E-13 2.55E-09 1.91E-12 1.75E-11 31 546 "NLN,ARL1,CENPBD1P1,SLC5A8,PCCA,CFL2,ZNF595,NRXN1,SMIM14,ATAD2B,HEATR5A,VCAN,SNX17,DMXL1,RAN,IPO4,RGS4,CLIP4,POLR1D,FAM172A,NDUFAF7,FBXO11,P2RX2,LIMCH1,PCDH17,GPR161,ACTR6,VRK2,ZNF84,IL6ST,PLB1" MicroRNA hsa-miR-4296:mirSVR_highEffct hsa-miR-4296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.98E-13 2.65E-09 1.98E-12 1.81E-11 28 443 "MDM4,APC,SNCAIP,PTGS2,PTPRC,RGS4,TXNDC15,RNF4,TRAPPC12,POLK,FOXO1,ZNF605,MEGF10,PDS5B,PCDH17,BRD8,MSH6,GTF3C2,YTHDC2,ZNF10,LINC00272,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,MFSD2B,AXDND1,SPATA13" MicroRNA hsa-miR-1914*:mirSVR_highEffct hsa-miR-1914*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.03E-13 2.68E-09 2.00E-12 1.83E-11 29 477 "ADD1,SLAMF6,FBRSL1,DDX55,BLZF1,NLRP4,AP1G2,NOVA1,RILPL1,UHMK1,BOD1L1,THAP6,RCHY1,C12orf65,UBXN2A,FCRL2,ATG10,CRYL1,GP6,VEZT,TM9SF1,PAICS,CCDC88A,JPH4,PCDH17,COMMD6,ZNF876P,ANKDD1B,LCP1" MicroRNA hsa-miR-107:TargetScan hsa-miR-107 TargetScan 5.21E-13 2.77E-09 2.07E-12 1.90E-11 32 584 "ABL2,ADD1,CUL4A,MCFD2,ARHGAP5,BCL2L2,NOVA1,PDE4D,CHD1,NUP37,ATAD2B,CLOCK,CSNK1G3,G3BP2,PPP2R3C,RAN,REST,RGS4,LATS2,SBNO1,MBNL2,ETF1,CLIP1,FOXG1,GABRB1,NPAS3,PCDH17,PPIP5K2,GPR12,MSH6,PAPPA2,FAM49A" MicroRNA hsa-miR-103a-3p:TargetScan hsa-miR-103a-3p TargetScan 5.21E-13 2.77E-09 2.07E-12 1.90E-11 32 584 "ABL2,ADD1,CUL4A,MCFD2,ARHGAP5,BCL2L2,NOVA1,PDE4D,CHD1,NUP37,ATAD2B,CLOCK,CSNK1G3,G3BP2,PPP2R3C,RAN,REST,RGS4,LATS2,SBNO1,MBNL2,ETF1,CLIP1,FOXG1,GABRB1,NPAS3,PCDH17,PPIP5K2,GPR12,MSH6,PAPPA2,FAM49A" MicroRNA hsa-miR-220b:mirSVR_highEffct hsa-miR-220b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.23E-13 2.78E-09 2.08E-12 1.90E-11 33 621 "IL17D,AACS,NFATC4,CDKL2,RCBTB2,WDFY2,PKP1,LYSMD3,CSNK1G3,SACS,ATG10,N4BP2L2,SUPT20H,VEZT,BRMS1L,PLEKHA6,UFM1,TADA1,SLC12A2,MYO16,TMEM183A,MCCC2,METAP2,C5orf56,DOCK9,COP1,AP4S1,LTB4R2,TXK,CCDC169,LINC00272,CHPT1,ANKDD1B" MicroRNA hsa-miR-767-5p:mirSVR_highEffct hsa-miR-767-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.43E-13 2.89E-09 2.16E-12 1.97E-11 36 737 "CUL4A,SNX24,ARHGEF7,PCDH9,CFAP54,LYSMD3,NGDN,CSNK1G3,C12orf65,G3BP2,RNF219,DNMT3A,EGLN3,POLR1D,RNASEL,LGR6,CWC27,SAP18,FGF9,POLK,FOXG1,FMO1,NUBPL,WDCP,C1orf112,PDS5B,CD244,NPAS3,METAP2,TDG,CRB1,NPL,ADAMTS19,SLAIN1,KCNN2,RMST" MicroRNA hsa-let-7b:mirSVR_highEffct hsa-let-7b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.49E-13 2.92E-09 2.18E-12 2.00E-11 37 777 "MDM4,SLAMF6,HOMEZ,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,SPATA18,CEP120,PTPRC,PARPBP,NR1H4,ATG10,RNF31,RGS12,CWC27,PCGF3,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,MAST4,ACSL6,CRB1,ZNF10,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-191:mirSVR_highEffct hsa-miR-191:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.66E-13 3.01E-09 2.24E-12 2.05E-11 25 349 "MDM4,COG6,PITPNM2,PNP,CACNA1E,FCHO2,ZNF664,PCCA,CDK17,SPATA18,PIGG,CEP120,DTD2,PIBF1,ZCCHC8,BRMS1L,LIMCH1,RAPGEF6,ATP8A2,NPAS3,PPARGC1A,GUF1,ZMYM2,FAM151B,SPRYD7" MicroRNA "TGCCTTA,MIR-124A:MSigDB" "TGCCTTA,MIR-124A:MSigDB" MSigDB 5.66E-13 3.01E-09 2.24E-12 2.05E-11 30 514 "MAP1B,SEMA6A,APBB2,KCTD12,ARHGEF7,MPZL1,FAM177A1,CDK18,SNX6,STRN3,LYSMD3,SNCAIP,PRKD1,SREK1,DMXL1,F11R,GNPDA2,ARGLU1,ELK3,ZNF219,ETF1,NR5A2,LIMCH1,NFASC,LPIN1,XPO4,SLC7A8,ATP6V0A2,SELENOI,ZDHHC20" MicroRNA hsa-miR-520c-3p:PITA hsa-miR-520c-3p:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-302a:PITA hsa-miR-302a:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-520d-3p:PITA hsa-miR-520d-3p:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-302b:PITA hsa-miR-302b:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-302c:PITA hsa-miR-302c:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-373:PITA hsa-miR-373:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-520a-3p:PITA hsa-miR-520a-3p:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-302d:PITA hsa-miR-302d:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-302e:PITA hsa-miR-302e:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-520e:PITA hsa-miR-520e:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-372:PITA hsa-miR-372:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-520b:PITA hsa-miR-520b:PITA_TOP PITA 6.07E-13 3.23E-09 2.38E-12 2.18E-11 31 551 "ABL2,MAP1B,ULK1,APBB2,ARHGEF7,PCDH9,DCLK1,FAM177A1,CFL2,ATAD2B,LYSMD3,GNPDA2,CLIP4,NTN4,LATS2,MBNL2,ETF1,DNAJC27,FNIP1,RELL1,SUCO,FBXO11,BRMS1L,SLC22A5,MYT1L,NPAS3,ERBIN,PCDH17,KMT5C,KLF12,ZBTB41" MicroRNA hsa-miR-1304:mirSVR_highEffct hsa-miR-1304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.16E-13 3.27E-09 2.42E-12 2.21E-11 37 780 "SLC4A4,CACNA1E,CDKL2,AMDHD1,RGSL1,GLT1D1,PFKFB2,POLN,AKAP6,SREK1,EGLN3,FAM129A,ATG10,PACRGL,UGT2A3,ARSK,DLEU1,PCGF3,GORAB,PAICS,SCYL2,FAM114A1,JPH4,GJB6,KDM3B,NFASC,KLHL20,GJB2,MAST4,ADGRA3,TMPO,UBE2K,ARHGAP30,TECRL,MZF1,TTC41P,LMNB1" MicroRNA hsa-miR-151-5p:mirSVR_lowEffct hsa-miR-151-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.22E-13 3.31E-09 2.44E-12 2.23E-11 33 625 "TBC1D14,SEMA6A,HOMEZ,ASCL1,ATP12A,B4GALT3,CARMIL3,FCRL3,NFATC4,TAF1B,CDK18,GLT1D1,EPN1,PIGG,DCT,PTPRC,PCOTH,CWC27,STK32B,ARL6IP4,TOMM40L,PIBF1,MBIP,SLC30A6,PKD2L2,SLC22A4,NMNAT2,LRCH1,DOCK9,SLC7A8,TPO,PAPPA2,ZNF324B" MicroRNA hsa-miR-2909:mirSVR_lowEffct hsa-miR-2909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.39E-13 3.40E-09 2.50E-12 2.29E-11 42 989 "NDRG2,CUL4A,BCL2L2,BTF3,RAB29,TAF1B,CAST,SNTG2,STRN3,FAM163A,TAPT1,SNCAIP,KIAA0040,SPATA18,OCIAD1,PARPBP,FAM129A,PACRGL,DCUN1D2,CWC27,F10,TOMM40L,SUCO,FBXO11,UFM1,POTEM,N4BP2,WDCP,EFR3B,GJA3,INSM2,MTUS2,MSH6,AP4S1,TMPO,NPL,SLAIN1,PAPPA2,NPHS2,KIF3C,LCP1,LINC00442" MicroRNA hsa-miR-552:mirSVR_highEffct hsa-miR-552:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.53E-13 3.47E-09 2.55E-12 2.34E-11 38 822 "MATN3,MSH2,FAM193A,CD84,NOVA1,CAST,PDGFRA,WDFY2,ATAD2B,SPATA18,PTGS2,OCIAD1,ARGLU1,CLIP4,EFNA5,GRTP1,MBNL2,ADGRV1,PIBF1,SELP,FLT3,TM9SF1,CGREF1,CHFR,MYO16,GABRA2,GABRB1,INSM2,DOCK9,ZBTB49,RASSF6,IL6ST,PLB1,FAM151B,FIP1L1,RMST,LMNB1,IFT88" MicroRNA hsa-miR-3122:mirSVR_highEffct hsa-miR-3122:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.54E-13 3.48E-09 2.56E-12 2.34E-11 32 589 "RALGAPA1,NOVA1,CAST,PCDH9,PCK2,PCSK1,GPR180,CKMT2,CEP120,RABGAP1L,PARPBP,CLIP4,EFNA5,ABCA11P,FCGR2B,FCGR3A,FCGR3B,N4BP2L2,SUPT20H,JPH4,RBKS,MCCC2,NEDD1,TMED2,ANO4,ACSL6,ACTR6,MAEL,TPO,HSP90B1,NPHS2,LCP1" MicroRNA hsa-miR-330-3p:PITA hsa-miR-330-3p:PITA_TOP PITA 6.66E-13 3.54E-09 2.60E-12 2.38E-11 35 703 "MAP1B,APBB2,APC,ATP2B4,CADM3,FCHO2,PCDH9,DCLK1,CSNK1G3,TBC1D4,OCIAD1,RASA1,CLIP4,NTN4,RNF4,MBNL2,ELF1,ETF1,PCGF3,SUCO,FOXG1,FOXO1,SLC12A2,ERBIN,PCDH17,METAP2,XPO4,TDG,SLAIN1,POC5,NSD2,DCP2,ZBTB41,KIF2A,PABPN1" MicroRNA hsa-miR-3653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-13 3.61E-09 2.65E-12 2.43E-11 33 627 "ABL2,TMEM132B,SLC4A4,BCL2L2,CD84,RILPL1,THAP6,CEP135,PIGG,RABGAP1L,SLC35F6,ZNF329,POLR1D,DCUN1D2,DLEU1,TLR6,PCBD2,FCAR,VEZT,ZCCHC8,DDX51,BRMS1L,NUBPL,ZNF667,UGGT2,SPIC,RASSF6,GPN1,TXK,DCP2,ZNF84,IRF1,FAM151B" MicroRNA hsa-miR-302e:mirSVR_highEffct hsa-miR-302e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.79E-13 3.61E-09 2.65E-12 2.43E-11 44 1078 "KIAA1211,B4GALT3,CCNA1,FCRLB,RFLNA,PCDH9,FAM177A1,XPR1,RGSL1,CFL2,JAKMIP1,THAP6,LYSMD3,CRHBP,ITSN2,CEP135,DMXL1,GNPDA2,CLIP4,NTN4,RNASEL,LATS2,DRAM1,DNAJC27,IRF9,RELL1,POLK,SUCO,HSD17B7,VEZT,FBXO11,BRMS1L,ARHGEF40,MYT1L,ZBTB37,PPIP5K2,GPR12,KMT5C,TDG,CRB1,ARHGAP30,C12orf73,KCNN2,IFT88" MicroRNA hsa-miR-29c-3p:TargetScan hsa-miR-29c-3p TargetScan 6.83E-13 3.63E-09 2.66E-12 2.43E-11 40 906 "PITPNM2,APC,ATP2B4,BCL2L2,NFATC4,GAS2L3,CDKL2,CAMK4,PCDH9,CFL2,ATAD2B,HOMER1,NCOR2,DNM3,F11R,MTX3,DNMT3A,REST,POLR1D,EFNA5,PCGF3,SCYL2,CCDC88A,N4BP2,CHFR,MYO16,GABRB1,KDM5B,NPAS3,PCDH17,PPARGC1A,PPIP5K2,METAP2,EML4,KLF12,HMGCR,DCP2,IGF1,LMLN,LOX" MicroRNA hsa-miR-29a-3p:TargetScan hsa-miR-29a-3p TargetScan 6.83E-13 3.63E-09 2.66E-12 2.43E-11 40 906 "PITPNM2,APC,ATP2B4,BCL2L2,NFATC4,GAS2L3,CDKL2,CAMK4,PCDH9,CFL2,ATAD2B,HOMER1,NCOR2,DNM3,F11R,MTX3,DNMT3A,REST,POLR1D,EFNA5,PCGF3,SCYL2,CCDC88A,N4BP2,CHFR,MYO16,GABRB1,KDM5B,NPAS3,PCDH17,PPARGC1A,PPIP5K2,METAP2,EML4,KLF12,HMGCR,DCP2,IGF1,LMLN,LOX" MicroRNA hsa-miR-29b-3p:TargetScan hsa-miR-29b-3p TargetScan 6.83E-13 3.63E-09 2.66E-12 2.43E-11 40 906 "PITPNM2,APC,ATP2B4,BCL2L2,NFATC4,GAS2L3,CDKL2,CAMK4,PCDH9,CFL2,ATAD2B,HOMER1,NCOR2,DNM3,F11R,MTX3,DNMT3A,REST,POLR1D,EFNA5,PCGF3,SCYL2,CCDC88A,N4BP2,CHFR,MYO16,GABRB1,KDM5B,NPAS3,PCDH17,PPARGC1A,PPIP5K2,METAP2,EML4,KLF12,HMGCR,DCP2,IGF1,LMLN,LOX" MicroRNA hsa-miR-591:mirSVR_highEffct hsa-miR-591:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.88E-13 3.66E-09 2.68E-12 2.45E-11 28 449 "SMIM15,FBRSL1,CDKL2,PDE4D,CENPC,PGGT1B,IFT172,LINC01257,NR1I3,AASDH,NTN4,RNASEL,N4BP2L2,FBXO11,SCYL2,SLC15A4,LIMCH1,GABRA2,NAAA,OXGR1,BAZ1A,HEXB,TECRL,YTHDC2,TADA2B,CCDC190,KIR2DS4,KIT" MicroRNA hsa-miR-764:mirSVR_highEffct hsa-miR-764:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.99E-13 3.72E-09 2.72E-12 2.49E-11 31 554 "MSH2,NCOA1,CCNB1IP1,KCTD12,ARHGEF7,NOVA1,CAST,AKAP6,COPA,SNCAIP,SPATA18,PARPBP,SMC6,DTD2,RNASEL,FAM172A,CLIP1,F10,TOMM40L,N4BP2L2,PIBF1,THADA,DRC1,LRCH1,SULT1E1,LPIN1,STRN,ADAMTS19,CHPT1,DNAH10,LMNB1" MicroRNA hsa-miR-938:mirSVR_lowEffct hsa-miR-938:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.28E-13 3.87E-09 2.83E-12 2.59E-11 38 825 "IL17D,BIRC6,ATP2B4,BCL2L2,MPZL1,AKAP6,RCHY1,BRI3BP,OCIAD1,PARPBP,EGLN3,RGS4,EIF2B1,ELF1,GORAB,TM9SF1,PLEKHA6,IVNS1ABP,ZNF605,WDCP,NR5A2,JPH4,KDM3B,TMED2,AP4S1,RIMBP2,HAL,TNR,HSD17B4,TENT2,YTHDC2,ZNF470,PGAM5,KIF2A,KIF3C,AXDND1,PABPN1,ZNF304" MicroRNA hsa-miR-217:TargetScan hsa-miR-217 TargetScan 7.51E-13 3.99E-09 2.92E-12 2.67E-11 24 323 "ABL2,NOVA1,RILPL1,ATAD2B,HOMER1,CLOCK,G3BP2,REST,DLEU1,FOXG1,FBXO11,BRMS1L,PDS5B,RAPGEF6,NPAS3,PCDH17,PPARGC1A,COX18,NT5C1B,MSH6,KLF12,DCP2,KIF2A,NT5C1B-RDH14" MicroRNA hsa-miR-593*:mirSVR_highEffct hsa-miR-593*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.73E-13 4.11E-09 3.00E-12 2.74E-11 33 630 "SMIM15,AACS,ATP2B4,PAH,PIGR,UBXN2A,NOS1AP,FBXL5,TBC1D4,G3BP2,TSEN15,NR1I3,RAN,RNF31,OGFOD2,TXNDC15,DCUN1D2,LGR6,SAP18,SUPT20H,UFM1,THADA,WDCP,NPAS3,SRP72,AP4S1,HSP90B1,PLB1,CCDC190,ZMYM2,EP400P1,AXDND1,IFT88" MicroRNA hsa-miR-101-3p.1:TargetScan hsa-miR-101-3p.1 TargetScan 8.75E-13 4.65E-09 3.39E-12 3.10E-11 34 671 "MDM4,DHX37,PPFIA4,APC,KCTD12,NOVA1,CDK18,PDE4D,CHD1,PIK3C2B,ATAD2B,POU2F1,PTGS2,CEP350,G3BP2,MTX3,DNMT3A,RASA1,EFNA5,MBNL2,FGFR3,FOXO1,NR5A2,PDS5B,KDM3B,LRCH1,GRSF1,RIMBP2,KLF12,PAPPA2,LHX9,KIF2A,KIT,LMNB1" MicroRNA hsa-miR-1468:mirSVR_lowEffct hsa-miR-1468:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.82E-13 4.69E-09 3.42E-12 3.13E-11 31 559 "NLN,BCL2L2,CD84,MPZL1,RILPL1,SCARB1,CHD1,ATAD2B,BRI3BP,PIGG,F11R,RABGAP1L,ARSK,CWC27,DLEU1,TOMM40L,GORAB,FBXO11,MBIP,NR5A2,ERAP1,PSME4,GOLGA3,TMPO,UBE2K,HSD17B4,DCP2,ZFHX2,KIF2A,PABPN1,LTA4H" MicroRNA hsa-miR-1207-5p:mirSVR_highEffct hsa-miR-1207-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.96E-13 4.77E-09 3.47E-12 3.18E-11 37 790 "ABL2,APC,NOVA1,PNP,NRL,ZNF595,POLE,THTPA,SNCAIP,CEP350,TBC1D4,TINF2,DNMT3A,EFS,ARSK,ETF1,PCGF3,FLT1,RUBCNL,CCDC92,ARHGEF40,MEGF10,ERAP1,ZNF544,RIPK3,CRB1,NPL,PAPPA2,TPTE2,JCHAIN,TADA2B,ZNF470,IL6ST,PGAM5,TTC41P,MFSD2B,PABPN1" MicroRNA hsa-miR-362-3p:mirSVR_highEffct hsa-miR-362-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.00E-13 4.79E-09 3.48E-12 3.19E-11 36 750 "ATP6V1G3,NOVA1,FAM177A1,CDK17,PDE4D,PDGFRA,TM9SF2,LYSMD3,IL20,CSNK1G3,PRKD1,MEMO1,NTN4,PCGF3,TOMM40L,FBXO11,NBEA,NUBPL,P2RX2,ZNF667,UGGT2,RAPGEF6,CENPJ,GJA3,MAST4,DOCK9,TDG,TGFBI,MAEL,STARD4,IL6ST,LHX9,SPRYD7,AXDND1,PABPN1,ZNF304" MicroRNA hsa-miR-762:mirSVR_highEffct hsa-miR-762:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.12E-13 4.85E-09 3.52E-12 3.23E-11 34 672 "NDRG2,AP1G2,DAOA,CBLN3,PAH,CDK17,ZNF595,WDFY2,MRPL57,ITGBL1,BOD1L1,POU2F1,CEP135,UBXN2A,RNF219,EIF2D,EFNA5,TRIM28,ZNF219,ETF1,DLEU1,RUBCNL,SCYL2,ARHGEF40,DCAF11,NFASC,LPIN1,NCSTN,NT5C1B,IGSF8,IL6ST,TMEM178A,RNASE11,RMST" MicroRNA hsa-miR-665:mirSVR_highEffct hsa-miR-665:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.17E-13 4.88E-09 3.54E-12 3.24E-11 33 634 "MDM4,NDRG2,DDX55,NEDD8,RAB29,PNP,CAST,RCBTB2,PFKFB2,ZNF595,TOGARAM2,FCRL5,SPATA18,NR1I3,NR1H4,PACRGL,MARVELD2,BORA,CWC27,NDUFAF7,GORAB,SDC1,JPH4,OXGR1,ARHGEF28,RNF212,GPN1,ZNF10,PLB1,KCNN2,DIAPH3,TTC41P,RMST" MicroRNA hsa-miR-766:mirSVR_highEffct hsa-miR-766:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.36E-13 4.98E-09 3.61E-12 3.31E-11 36 751 "LRRC43,ZNF542P,RAB29,PCCA,VIT,PTPRVP,AKAP6,TAPT1,POU2F1,FAM169A,DNM3,EIF2AK2,ZNF586,PTPRC,RAN,RGS4,GUSBP3,MARVELD2,PIBF1,GABRB1,RAPGEF6,ZNF274,SRP72,DRC1,ZBTB37,TDG,NCSTN,TGFBI,TMEM174,ZNF550,ZNF876P,IL25,IGF1,ZBED3-AS1,KIR2DL1,KIR2DS4" MicroRNA hsa-miR-515-3p:mirSVR_highEffct hsa-miR-515-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.90E-13 5.26E-09 3.82E-12 3.49E-11 34 674 "ADD1,ATP1A2,LINC02347,NOVA1,PCCA,CDK18,RCBTB2,THAP6,HOMER1,AKAP6,MPC2,TAPT1,EPGN,CLOCK,LACC1,SPATA18,CLIP4,CRYL1,BORA,DRAM1,DNAJC27,SUCO,NUBPL,UFM1,SCYL2,TMEM183A,IQGAP2,DOCK9,NT5C1B,LINC01551,NPL,FAM151B,SPRYD7,AXDND1" MicroRNA hsa-miR-186-5p:Functional MTI Functional MTI miRTarbase 1.01E-12 5.37E-09 3.89E-12 3.56E-11 36 753 "ULK1,APC,KCTD12,BTF3,PNP,CAD,UHMK1,FAM177A1,SNX6,ITSN2,MATR3,PSME1,PIGG,FBXL5,MTX3,TSEN15,RAN,ZNF256,TBC1D19,DNAJC27,ARL6IP4,FNIP1,FOXO1,G2E3,SLC15A4,TMEM183A,KDM3B,IKBIP,TMED2,SCFD1,KMT5A,SNRNP35,NCSTN,UBE2K,ZNF324B,KIT" MicroRNA hsa-miR-1193:mirSVR_highEffct hsa-miR-1193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-12 5.39E-09 3.90E-12 3.57E-11 31 562 "LINC02347,MPZL1,LDB2,FCGR2C,PDE4D,PDGFRA,THAP6,IL20,FBXL5,SUPT7L,C14orf119,MBNL2,KLHL12,FLT3,TM9SF1,SLC8A1,NR5A2,KIF21B,NMNAT2,RAPGEF6,TMEM183A,METAP2,RIPK3,VRK2,FAM151B,NPHS2,KIR2DL4,KIR2DS4,KIT,LINC00442,LOX" MicroRNA hsa-miR-299-5p:mirSVR_highEffct hsa-miR-299-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-12 5.54E-09 4.01E-12 3.67E-11 33 637 "KCTD12,CD84,AMDHD1,FAM177A1,PFKFB2,NRXN1,THAP6,POU2F1,LACC1,LRRTM2,ZNF586,CEP350,G3BP2,PARPBP,TMEM161B,UGT2A3,MAEA,ETF1,USP44,GORAB,FNIP1,FOXG1,UFM1,CCDC88A,PKD2L2,MEGF10,IQGAP2,RASSF6,TECRL,PAPPA2,ZNF470,ZMYM2,LOX" MicroRNA hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 1.10E-12 5.86E-09 4.23E-12 3.88E-11 23 299 "BIRC6,NCOA1,CADM3,BCL2L2,FCHO2,CDK17,PDGFRA,LYSMD3,DNM3,EIF2AK2,MATR3,RAN,REST,SBNO1,FGF9,PPARGC1A,ATP11A,ACSL6,NCSTN,GPR161,NPL,LHX9,LMNB1" MicroRNA hsa-let-7c:mirSVR_highEffct hsa-let-7c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.21E-12 6.41E-09 4.63E-12 4.24E-11 37 798 "MDM4,SLAMF6,HOMEZ,WDR19,SLC4A4,SLC5A6,NOVA1,ZNF595,ITGBL1,PTPRVP,GNPTAB,POU2F1,CEP135,SPATA18,CEP120,PTPRC,PARPBP,ATG10,RNF31,RGS12,CWC27,PCGF3,FCGR2B,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,MAST4,ACSL6,CRB1,ZNF10,SPRYD7,AXDND1,LMNB1" MicroRNA hsa-miR-3146:mirSVR_highEffct hsa-miR-3146:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-12 7.00E-09 5.06E-12 4.63E-11 34 681 "NLN,APC,FCHO2,SLC5A8,PIWIL1,ITGBL1,CPNE6,CFAP45,JAKMIP1,GNPTAB,LRRTM2,SREK1,G3BP2,C14orf119,DNMT3A,FAM129A,EIF2D,DLEU1,USP44,POLK,FBXO11,OXGR1,CMPK2,KLHL20,COMMD6,NPFFR2,ADGRL3,ARHGEF28,ADAMTS19,ZNF10,KCNT2,JCHAIN,ZNF470,SKA3" MicroRNA hsa-miR-3161:mirSVR_highEffct hsa-miR-3161:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-12 7.14E-09 5.15E-12 4.71E-11 38 842 "RALGAPA1,SFTA3,SMIM15,NLN,NOVA1,PNP,SLC5A8,NRXN1,THAP6,AKAP6,CSNK1G3,DNM3,PIGG,NUDT12,TSEN15,ARGLU1,RGS12,ARSK,CLIP1,UTP15,SUCO,FMO1,SUPT20H,VEZT,FBXO11,THADA,PDS5B,RAPGEF6,PPARGC1A,MAST4,PSME4,ARHGEF28,RNF212,NT5C1B,CRB1,HAL,ADAMTS19,AXDND1" MicroRNA hsa-miR-96:mirSVR_highEffct hsa-miR-96:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.39E-12 7.40E-09 5.34E-12 4.89E-11 40 927 "ATP2B4,ARHGEF7,CCNA1,NOVA1,CACNA1E,LDB2,PCDH9,PCSK1,CDK17,VIT,PGGT1B,GPR180,BOD1L1,THAP6,HOMER1,LYSMD3,ITSN2,GLT8D2,DMXL1,TBC1D4,NTN4,GUSBP3,TXNDC15,SAP18,FOXO1,SUPT20H,NUBPL,SLC22A5,MYO16,CENPJ,OXGR1,PSME4,METAP2,GPR12,SLAIN1,YTHDC2,ZNF10,ZMYM2,LCP1,RMST" MicroRNA hsa-miR-3173:mirSVR_highEffct hsa-miR-3173:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-12 7.51E-09 5.41E-12 4.96E-11 44 1102 "APAF1,STARD13,NEDD8,NOVA1,CACNA1E,CBLN3,ZNF664,COPA,VCAN,ZFYVE16,SPATA18,DCT,CEP120,PTPRC,F11R,SUPT7L,RB1,NTN4,EIF2B1,BORA,ZNF671,CWC27,STK32B,N4BP2L2,FMO1,TADA1,CCDC88A,MRPS14,NAAA,SRP54,SRP72,KLHL20,COP1,SLC7A8,HAL,TNR,NPL,ZNF26,PLB1,FIP1L1,KIF3C,KIR2DL1,LINC00442,AXDND1" MicroRNA hsa-miR-2114:mirSVR_highEffct hsa-miR-2114:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-12 7.90E-09 5.69E-12 5.21E-11 30 534 "ADD1,ACOX3,BCL2L2,FCGR2C,PCK2,RGSL1,CFL2,PM20D1,THTPA,EPGN,SNCAIP,DCAF8,LOC439933,C14orf119,SNORA49,EFS,IRF9,PIBF1,FLT3,MRPS14,MEGF10,DRC1,PPARGC1A,RNF17,TGM1,LINC01551,GTF2H3,GPN1,KCNT2,IL6ST" MicroRNA hsa-miR-455-5p:mirSVR_highEffct hsa-miR-455-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.55E-12 8.23E-09 5.92E-12 5.42E-11 34 685 "STXBP6,CAMK4,CAST,PDGFRA,PTPRVP,RCHY1,ZFYVE16,FBXL5,RGS4,TXNDC15,SPATA9,BORA,ADGRV1,USP44,PCBD2,FCAR,FGF9,RUBCNL,IVNS1ABP,KDM3B,LRCH1,ERBIN,TMED2,TCF7,DOCK9,HEXB,UBE2K,ZNF876P,TENT2,WDR36,NSD2,ZNF10,IL6ST,KCNN2" MicroRNA hsa-miR-371-5p:mirSVR_highEffct hsa-miR-371-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.57E-12 8.34E-09 6.00E-12 5.49E-11 42 1017 "SMIM15,NLN,KCTD12,FGFRL1,PNP,ZNF664,ZMYM5,CDK18,CFL2,PGGT1B,CEP135,FAM129A,SMC6,GUSBP3,RNASEL,MBNL2,ELK3,CWC27,ELOVL7,GORAB,SUCO,HSD17B7,TM9SF1,RUBCNL,ALKAL2,UFM1,UGGT2,RAPGEF6,KDM3B,EML4,YIPF7,FCRLA,GTF2H3,BAZ1A,RASSF6,TECRL,ANKS1B,ZMYM2,ZBED3-AS1,TTC41P,SPRYD7,IFT88" MicroRNA hsa-miR-4313:mirSVR_lowEffct hsa-miR-4313:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-12 8.60E-09 6.18E-12 5.66E-11 47 1243 "LRRC43,NYNRIN,BLZF1,CD84,CAST,PIGR,ADGRF3,HECTD1,FAM53A,C12orf65,CMTM5,UBXN2A,FCRL5,ZFYVE16,EPS8L1,KLHL3,CEP120,PTPRH,DNMT3A,EMC9,GUSBP3,ZNF219,DRAM1,CWC27,IRF9,NDUFAF7,POLK,RASA3,ZNF605,GABRB1,PDS5B,NPAS3,LILRB1,IKBIP,ZBTB37,LPIN1,LILRB4,FCRLA,GRSF1,RAB2B,TMPO,FZD10,TNR,PLB1,IRF1,LAD1,PABPN1" MicroRNA hsa-miR-361-3p:mirSVR_lowEffct hsa-miR-361-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-12 8.74E-09 6.27E-12 5.74E-11 52 1480 "RALGAPA1,ADD1,PPFIA4,AACS,NCOA1,ZNF542P,KCTD12,NFATC4,SLC5A6,RAB29,NRL,CAST,PCK2,PDGFRA,AKAP6,TOGARAM2,BRI3BP,DNM3,EPS8L1,LOC439933,NUDT12,DNMT3A,OGFOD2,POLR1D,RNASEL,EFNA5,FCAMR,DLEU1,PCGF3,IRF9,FCGR2B,LRRN2,VEZT,THADA,KIF21B,PDS5B,TMED2,DOCK9,FCRLA,CRB1,AP4S1,GTF3C2,GPN1,NSD2,YTHDC2,TADA2B,ZNF470,ZNF324B,C12orf73,KIT,PABPN1,SPATA13" MicroRNA hsa-miR-24-1*:mirSVR_highEffct hsa-miR-24-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-12 9.01E-09 6.46E-12 5.92E-11 26 399 "COG6,AMDHD1,CHAMP1,PCDH9,COG3,G3BP2,LINC01257,FAM129A,ATG10,REST,NDUFAF7,FGF9,TNFRSF19,TADA1,LIMCH1,TMEM183A,ERBIN,COMMD6,DOCK9,NSD2,IGF1,ZNF470,ZMYM2,FAM151B,ZBED3-AS1,NUAK2" MicroRNA hsa-miR-1228:mirSVR_highEffct hsa-miR-1228:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.77E-12 9.42E-09 6.75E-12 6.18E-11 29 502 "NLN,ATP6V1G3,NOP14,CACNA1E,CAMK4,PCDH9,ZNF595,NRXN1,CSNK1G3,NUDT12,RAN,FAM129A,CLIP4,LATS2,ARSK,CLIP1,FOXG1,P2RX2,PDS5B,ATP8A2,DRC1,DOCK9,NCSTN,TGFBI,GUF1,PAPPA2,ZMYM2,ANKDD1B,MFSD2B" MicroRNA hsa-miR-621:mirSVR_highEffct hsa-miR-621:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-12 9.53E-09 6.83E-12 6.25E-11 26 400 "ABL2,COG6,SEMA6A,CDKL4,ARHGEF7,CD1D,SLC5A8,PDE4D,CFL2,PFKFB2,GPR180,POU2F1,PREPL,ZNF586,PARPBP,POLR1D,EIF2D,MARVELD2,MAEA,YPEL5,EFR3B,RNF212,TMPO,HTR2A,WDR36,JCHAIN" MicroRNA hsa-miR-4322:mirSVR_highEffct hsa-miR-4322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-12 1.09E-08 7.83E-12 7.17E-11 28 470 "MDM4,APC,RGSL1,SNCAIP,PTGS2,PTPRC,RGS4,TXNDC15,RNF4,TRAPPC12,MARVELD2,POLK,FOXO1,ZNF605,MEGF10,PDS5B,PCDH17,BRD8,MSH6,GTF3C2,ZNF10,LINC00272,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,AXDND1,SPATA13" MicroRNA hsa-miR-504:mirSVR_lowEffct hsa-miR-504:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-12 1.10E-08 7.89E-12 7.22E-11 51 1441 "MAP1B,SEMA6A,APAF1,AACS,ZNF542P,ATP7B,NFATC4,RILPL1,FCRLB,C1orf116,RCHY1,POU2F1,LYSMD3,NCOR2,SNCAIP,SUPT7L,SLC35F6,C14orf119,TMEM161B,OGFOD2,RGS12,EFNA5,KIRREL1,DHRS2,FAM172A,ARSK,DNAJC27,F7,PCBD2,UTP15,TNFRSF19,SDC1,FLT1,HSD17B7,PAICS,NPAS3,MCCC2,ZBTB37,LPIN1,GOLGA3,LILRB4,ACSL6,TCF7,TENT2,NSD2,MZF1,TMEM178A,ANKDD1B,MFSD2B,LINC01913,SPATA13" MicroRNA hsa-miR-3127:mirSVR_highEffct hsa-miR-3127:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-12 1.11E-08 7.91E-12 7.25E-11 35 732 "CENPBD1P1,BCL2L2,CACNA1E,PDE4D,PIK3C2B,SNCAIP,ZNF586,SPATA18,LOC439933,PARPBP,OGFOD2,RGS12,TOMM40L,GORAB,N4BP2L2,TNFRSF19,CGREF1,LIMCH1,SNRPF,CIDEB,GAK,ANKLE2,BRD8,ADGRL3,NT5C1B,LINC01551,RIMBP2,NPL,HEXB,HPCAL1,STARD4,IL6ST,CHPT1,KIT,AXDND1" MicroRNA hsa-miR-3184:mirSVR_lowEffct hsa-miR-3184:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.15E-12 1.14E-08 8.16E-12 7.47E-11 60 1891 "CUL4A,PITPNM2,AACS,CENPBD1P1,SLC4A4,NLRP4,CADM3,AP1G2,ADGRD1,CCNB1,PIK3C2B,EPN1,PTPRVP,THTPA,LYSMD3,NGDN,CMTM5,FCRL5,NOS1AP,ZNF586,PIGG,KLHL3,TINF2,RABGAP1L,RABGGTA,CRYL1,STX2,GP6,FAM172A,STK32B,ABCA11P,CLIP1,TOMM40L,VEZT,ALKAL2,ARHGEF40,NR5A2,YPEL5,EFR3B,MYT1L,CIDEB,KDM5B,NMNAT2,JPH4,IQGAP2,LINC02393,CNTN2,LILRB4,RIPK3,FCRLA,TFDP1,SLC7A8,IGSF8,TPO,ADAMTS19,MZF1,ZNF84,KCNN2,FIP1L1,PABPN1" MicroRNA hsa-miR-218:PITA hsa-miR-218:PITA_TOP PITA 2.15E-12 1.14E-08 8.16E-12 7.47E-11 29 506 "MCC,BIRC6,TMEM132B,SEMA6A,ARHGAP5,FCHO2,DCLK1,PDGFRA,NRXN1,BIVM,RNF219,EGLN3,MBNL2,CCDC88A,SLC12A2,MYO16,MYT1L,KIF21B,SRP72,PPARGC1A,ANO4,DOCK9,RIMBP2,KLF12,ZBTB41,CAB39L,KIF2A,LMNB1,LOX" MicroRNA hsa-miR-4305:mirSVR_highEffct hsa-miR-4305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.15E-12 1.14E-08 8.16E-12 7.47E-11 29 506 "SMIM15,NLN,CUL4A,CDKL4,CBLN3,UHMK1,SLC5A8,PDE4D,CFL2,HOMER1,AKAP6,CLOCK,TBC1D4,POLR1D,LATS2,USP44,FCGR3B,YPEL5,LIMCH1,KDM5B,RBKS,ACSL6,FCRLA,STARD4,KCNT2,MZF1,ZFHX2,KIT,RMST" MicroRNA hsa-miR-488*:mirSVR_highEffct hsa-miR-488*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-12 1.18E-08 8.43E-12 7.72E-11 36 774 "BIRC6,COG6,STXBP6,NCOA1,CADM3,NOVA1,CAST,SLC5A8,ZNF664,FAM177A1,CDK18,PGGT1B,ITGBL1,LINC01085,BOD1L1,HEATR5A,ZFYVE16,NUDT12,CLIP4,SETDB2,GUSBP3,SAP18,UTP15,TOMM40L,GORAB,FNIP1,TADA1,CMPK2,KHNYN,RNF212,TXK,HTR2A,IL6ST,FAM151B,AXDND1,MICU2" MicroRNA hsa-miR-1294:mirSVR_highEffct hsa-miR-1294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.31E-12 1.23E-08 8.74E-12 8.00E-11 36 775 "PITPNM2,NOP14,ASTN1,ARHGEF7,NFKBIA,CAST,FCRLB,SNX6,LTB4R,HOMER1,RNASE9,SNCAIP,FCRL5,COG3,GNPDA2,PARPBP,C14orf119,NR1I3,AASDH,MEMO1,ZNF419,ADGRV1,SLC22A17,IRF9,FCGR2B,FLT3,SGCG,MAST4,METAP2,YIPF7,FZD10,HEXB,IL6ST,ZMYM2,KIF3C,AXDND1" MicroRNA hsa-miR-181d:PITA hsa-miR-181d:PITA_TOP PITA 2.31E-12 1.23E-08 8.75E-12 8.01E-11 37 816 "MAP1B,MCC,BIRC6,TMEM132B,NLN,SLC4A4,PPP1R12B,NOVA1,CDKL2,CCNB1,UHMK1,DCLK1,PCSK1,PDGFRA,NRXN1,AKAP6,CSNK1G3,BIVM,CEP350,TBC1D4,G3BP2,MTX3,RAN,TXNDC15,MBNL2,ETF1,CLIP1,FNIP1,FBXO11,G2E3,NMNAT2,TBC1D1,PPIP5K2,TGFBI,HSP90B1,YTHDC2,ZBTB41" MicroRNA hsa-miR-181b:PITA hsa-miR-181b:PITA_TOP PITA 2.31E-12 1.23E-08 8.75E-12 8.01E-11 37 816 "MAP1B,MCC,BIRC6,TMEM132B,NLN,SLC4A4,PPP1R12B,NOVA1,CDKL2,CCNB1,UHMK1,DCLK1,PCSK1,PDGFRA,NRXN1,AKAP6,CSNK1G3,BIVM,CEP350,TBC1D4,G3BP2,MTX3,RAN,TXNDC15,MBNL2,ETF1,CLIP1,FNIP1,FBXO11,G2E3,NMNAT2,TBC1D1,PPIP5K2,TGFBI,HSP90B1,YTHDC2,ZBTB41" MicroRNA hsa-miR-519b-5p:mirSVR_highEffct hsa-miR-519b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-518e*:mirSVR_highEffct hsa-miR-518e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-519c-5p:mirSVR_highEffct hsa-miR-519c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-519a*:mirSVR_highEffct hsa-miR-519a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-522*:mirSVR_highEffct hsa-miR-522*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-523*:mirSVR_highEffct hsa-miR-523*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-12 1.24E-08 8.79E-12 8.05E-11 35 735 "RALGAPA1,MAP1B,SEMA6A,APAF1,NCOA1,NRXN1,AKAP6,THTPA,SNCAIP,OCIAD1,SUPT7L,EGLN3,DCUN1D2,EIF2B1,EFS,ADGRV1,IRF9,TNFRSF19,RELL1,FLT3,VEZT,PAICS,GABRB1,JPH4,NPAS3,ADAM17,GTF3C2,NPL,HEXB,GUF1,TMEM174,ZNF550,ZMYM2,LCP1,NUAK2" MicroRNA hsa-miR-220c:mirSVR_highEffct hsa-miR-220c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.39E-12 1.27E-08 9.01E-12 8.25E-11 36 776 "MDM4,ULK1,ATP7B,ZMYM5,CFL2,PFKFB2,SNX6,PITX1,PTPRVP,AKAP6,MPHOSPH8,FCRL5,OCIAD1,ZNF329,AASDH,MARVELD2,MAEA,ETF1,ELOVL7,USP44,GOLGA2P5,FBXO11,SLC22A4,GABRB1,CENPJ,ERAP1,NMU,DHRS4,ZNF544,PPIP5K2,ANO4,NCSTN,GTF3C2,ZNF550,ZMYM2,TTC41P" MicroRNA hsa-miR-181a:PITA hsa-miR-181a:PITA_TOP PITA 2.40E-12 1.28E-08 9.01E-12 8.25E-11 37 817 "MAP1B,MCC,BIRC6,TMEM132B,NLN,SLC4A4,PPP1R12B,NOVA1,CDKL2,CCNB1,UHMK1,DCLK1,PCSK1,PDGFRA,NRXN1,AKAP6,CSNK1G3,BIVM,CEP350,TBC1D4,G3BP2,MTX3,RAN,TXNDC15,MBNL2,ETF1,CLIP1,FNIP1,FBXO11,G2E3,NMNAT2,TBC1D1,PPIP5K2,TGFBI,HSP90B1,YTHDC2,ZBTB41" MicroRNA hsa-miR-181c:PITA hsa-miR-181c:PITA_TOP PITA 2.40E-12 1.28E-08 9.01E-12 8.25E-11 37 817 "MAP1B,MCC,BIRC6,TMEM132B,NLN,SLC4A4,PPP1R12B,NOVA1,CDKL2,CCNB1,UHMK1,DCLK1,PCSK1,PDGFRA,NRXN1,AKAP6,CSNK1G3,BIVM,CEP350,TBC1D4,G3BP2,MTX3,RAN,TXNDC15,MBNL2,ETF1,CLIP1,FNIP1,FBXO11,G2E3,NMNAT2,TBC1D1,PPIP5K2,TGFBI,HSP90B1,YTHDC2,ZBTB41" MicroRNA hsa-miR-330-3p:TargetScan hsa-miR-330-3p TargetScan 2.52E-12 1.34E-08 9.46E-12 8.66E-11 35 737 "APBB2,APC,ATP2B4,CADM3,CAMK4,FAM177A1,CSNK1G3,NOS1AP,NOP9,OCIAD1,RABGAP1L,DNMT3A,FAM129A,MBNL2,EFS,PCGF3,PCBD2,FOXO1,N4BP2,GABRB1,FAM114A1,RAPGEF6,CD244,ATP8A2,HSPH1,GJA3,ATP11A,METAP2,ACSL6,RAB2B,DCP2,PGAM5,FAM49A,LETM1,PABPN1" MicroRNA hsa-miR-4286:mirSVR_lowEffct hsa-miR-4286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.54E-12 1.35E-08 9.53E-12 8.72E-11 46 1213 "MDM4,RGS5,ZNF542P,NRL,AMDHD1,CCNB1,SCARB1,PFKFB2,WDFY2,MRPL57,ITGBL1,CPNE6,CFAP54,LTB4R,ZFYVE16,EPS8L1,F11R,G3BP2,PACRGL,ELK3,LGR6,FAM172A,ETF1,F7,FOXG1,MROH9,GOLGA2P5,PLEKHA6,ARHGEF40,SNRPF,ZNF274,ERAP1,ATP8A2,NFASC,LRCH1,ZNF544,RNF17,GTF3C2,RASSF6,HSP90B1,GPN1,DCP2,ZNF470,IRF1,LINC01913,ZNF304" MicroRNA hsa-miR-24:mirSVR_highEffct hsa-miR-24:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.60E-12 1.38E-08 9.75E-12 8.93E-11 33 659 "MATN3,CACNA1E,NFXL1,PDGFRA,PDE6B,ATAD2B,HEATR5A,SNCAIP,FCRL2,MATR3,SPATA18,PIGG,DMXL1,KLHL3,PTPRC,TINF2,RASA1,TMEM161B,FMO1,RUBCNL,ACIN1,DCAF11,CYP1B1-AS1,LRCH1,ACSL6,COP1,TPO,HSD17B4,TTC41P,LINC01913,RMST,LMNB1,LOX" MicroRNA hsa-miR-449c*:mirSVR_highEffct hsa-miR-449c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.60E-12 1.39E-08 9.76E-12 8.94E-11 31 583 "RALGAPA1,AACS,MPZL1,CD1E,FCRLB,JAKMIP1,CRHBP,LRRTM2,F11R,G3BP2,DNMT3A,RGS12,PACRGL,GP6,FNIP1,PIBF1,POLK,FBXO11,NUBPL,HSPH1,LRCH1,PPIP5K2,ADGRL3,RNF17,ADAMTS19,HTR2A,ZNF10,ZNF470,KCNN2,KIF2A,LMNB1" MicroRNA hsa-let-7b-5p:Functional MTI Functional MTI miRTarbase 2.68E-12 1.43E-08 1.01E-11 9.21E-11 46 1215 "MDM4,BIRC6,MIPEP,NOP14,KCTD12,FGFRL1,SLC5A6,NFKBIA,CCNA1,CCNB1,PDGFRA,CHD1,BRI3BP,CEP135,DNM3,PRKD1,SNX17,PIGG,PTGS2,DHX9,CEP120,MTX3,SLC35F6,TSEN15,IPO4,TMEM33,TRIM28,TBC1D19,PCGF3,UTP15,TOMM40L,NDUFAF7,SUPT20H,GFM2,POTEM,WDCP,PUS1,ZBTB37,PPARGC1A,STRN,BAZ1A,IGSF8,ZMYM2,KIF2A,SPRYD7,LTA4H" MicroRNA hsa-miR-4266:mirSVR_highEffct hsa-miR-4266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-12 1.45E-08 1.02E-11 9.37E-11 29 511 "ABL2,MDM4,BIRC6,SLAMF6,SNX24,CENPBD1P1,MYBPC1,SLC5A8,ZNF664,RGSL1,ITGBL1,THTPA,POU2F1,PSMA6,SPATA18,FBXL5,TINF2,DNAJC27,ABCA11P,TM9SF1,SLC12A2,YPEL5,TMEM183A,RAB2B,GUF1,ZFHX2,LHX9,KCNN2,AXDND1" MicroRNA hsa-miR-532-3p:mirSVR_highEffct hsa-miR-532-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-12 1.47E-08 1.03E-11 9.44E-11 32 622 "SNX24,ATP1A2,CD84,NEDD8,PNP,LDB2,CD1D,CD1E,PDE4D,WDFY2,NCR1,HECTD1,RNASE9,C12orf65,SREK1,TSEN15,DNMT3A,AASDH,FAM228A,RGS12,EFNA5,KLHL12,BORA,ETF1,VEZT,WDCP,RAPGEF6,ADGRA3,CRB1,TMPO,CHPT1,PABPN1" MicroRNA hsa-miR-1224-3p:mirSVR_highEffct hsa-miR-1224-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.78E-12 1.48E-08 1.04E-11 9.52E-11 28 476 "NDRG2,NYNRIN,SNX24,PNP,CDKL2,CD1D,MRPL57,CFAP54,ATAD2B,HECTD1,NGDN,ZFYVE16,LOC439933,DNMT3A,RGS12,KLHL12,ZNF219,ABCA11P,FNIP1,TNFRSF19,SUCO,THADA,MYT1L,MRPS27,NEDD1,ZNF721,IL6ST,PABPN1" MicroRNA hsa-miR-614:mirSVR_lowEffct hsa-miR-614:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.96E-12 1.57E-08 1.11E-11 1.01E-10 26 409 "ULK1,BCL2L2,NFATC4,MPZL1,ZMYM5,GLT1D1,FAM53A,CEP350,RNF31,MARVELD2,P2RX2,C1orf112,CYP1B1-AS1,MYO16,PDS5B,UTP20,CNTN2,ADGRA3,EML4,RNF17,MAEL,TXK,GALP,ZMYM2,KIR2DL4,IFT88" MicroRNA hsa-miR-425-5p:TargetScan hsa-miR-425-5p TargetScan 3.01E-12 1.60E-08 1.13E-11 1.03E-10 19 202 "CFL2,HECTD1,NOS1AP,MATR3,NOP9,RNF219,DNAJC27,FGF9,KIF21B,ATP8A2,HSPH1,GJA3,NT5C1B,RAB2B,IGF1,LHX9,CAB39L,NT5C1B-RDH14,PABPN1" MicroRNA hsa-miR-129-5p:Functional MTI Functional MTI miRTarbase 3.13E-12 1.66E-08 1.17E-11 1.07E-10 32 625 "ABL2,SEMA6A,APC,NCOA1,PDGFRA,PIWIL1,PITX1,HOMER1,STRN3,CLOCK,NGDN,BRI3BP,VCAN,BIVM,DMXL1,SLC35F6,MEMO1,ZNF419,SBNO1,SH3BP2,UFM1,TNFSF13B,GABRB1,ATP8A2,ZBTB37,LPIN1,ADAM17,LINC01551,IGF1,SELENOI,CCDC169,LHX9" MicroRNA hsa-miR-877:mirSVR_highEffct hsa-miR-877:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.30E-12 1.75E-08 1.23E-11 1.12E-10 37 826 "ABL2,CUL4A,ATP7B,CD1E,FAM177A1,ITGBL1,HOMER1,RCHY1,THTPA,PREPL,PSMA6,SPATA18,CEP350,PARPBP,C14orf119,DTD2,RGS4,RNASEL,ELF1,DEPDC4,SDC1,CCDC92,FAM114A1,NMNAT2,CMPK2,SRP72,ADGRL3,BAZ1A,RIMBP2,ATP6V0A2,GUF1,PAPPA2,HTR2A,STARD4,SPTSSA,TTC41P,RMST" MicroRNA hsa-miR-1299:PITA hsa-miR-1299:PITA_TOP PITA 3.30E-12 1.76E-08 1.23E-11 1.13E-10 26 411 "SFTA3,MAP1B,MCC,SEMA6A,NCOA1,CACNA1E,CHAMP1,TAPT1,F11R,G3BP2,WDR1,RASA1,POLR1D,MBNL2,KLHL12,ETF1,ELOVL7,TOMM40L,FOXO1,MYT1L,ERBIN,GJA3,MTUS2,SLC7A8,DCP2,LHX9" MicroRNA hsa-miR-519b-3p:PITA hsa-miR-519b-3p:PITA_TOP PITA 3.31E-12 1.76E-08 1.23E-11 1.13E-10 33 665 "MAP1B,BIRC6,ARL1,BCL2L2,FCHO2,PDGFRA,CFL2,RCHY1,DCAF8,ZFYVE16,FBXL5,CEP120,SACS,EGLN3,RB1,CLIP4,NTN4,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,MYT1L,KDM5B,ERBIN,KLHL20,RIMBP2,KLF12,UBC,SLAIN1,IGF1,KCNN2" MicroRNA hsa-miR-519a:PITA hsa-miR-519a:PITA_TOP PITA 3.31E-12 1.76E-08 1.23E-11 1.13E-10 33 665 "MAP1B,BIRC6,ARL1,BCL2L2,FCHO2,PDGFRA,CFL2,RCHY1,DCAF8,ZFYVE16,FBXL5,CEP120,SACS,EGLN3,RB1,CLIP4,NTN4,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,MYT1L,KDM5B,ERBIN,KLHL20,RIMBP2,KLF12,UBC,SLAIN1,IGF1,KCNN2" MicroRNA hsa-miR-519c-3p:PITA hsa-miR-519c-3p:PITA_TOP PITA 3.31E-12 1.76E-08 1.23E-11 1.13E-10 33 665 "MAP1B,BIRC6,ARL1,BCL2L2,FCHO2,PDGFRA,CFL2,RCHY1,DCAF8,ZFYVE16,FBXL5,CEP120,SACS,EGLN3,RB1,CLIP4,NTN4,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,MYT1L,KDM5B,ERBIN,KLHL20,RIMBP2,KLF12,UBC,SLAIN1,IGF1,KCNN2" MicroRNA hsa-miR-924:mirSVR_highEffct hsa-miR-924:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.43E-12 1.82E-08 1.27E-11 1.17E-10 38 869 "BLZF1,CD1E,SCFD2,PCSK1,PDE4D,PIWIL1,NRXN1,RCHY1,SYCP3,SNCAIP,DCAF8,BIVM,CEP350,B3GLCT,RASA1,SMC6,CWC27,UTP15,SUCO,CCDC88A,GABRA2,IQGAP2,ATP8A2,NPAS3,MIMT1,ADGRL3,RIPK3,KMT5A,DOCK9,YIPF7,COX18,TMPO,ATP6V0A2,GUF1,SLAIN1,ZMYM2,TDRD3,LOX" MicroRNA hsa-miR-510:mirSVR_highEffct hsa-miR-510:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.68E-12 1.96E-08 1.37E-11 1.25E-10 34 707 "SLAMF6,SLC4A4,BTF3,LDB2,ZNF664,ZMYM5,PDGFRA,PGGT1B,MATR3,SREK1,G3BP2,RABGAP1L,NR1I3,FAM129A,ATG10,SMC6,KLHL12,UTP15,FNIP1,N4BP2L2,RELL1,PIBF1,RUBCNL,SLC8A1,RAPGEF6,NPAS3,IKBIP,UGT2A1,ANO4,NT5C1B,HEXB,YTHDC2,ZNF26,FAM71C" MicroRNA hsa-miR-92b-3p:Functional MTI Functional MTI miRTarbase 3.97E-12 2.11E-08 1.47E-11 1.35E-10 34 709 "MAP1B,ATP2B4,CAD,FCHO2,CCNB1,XPR1,HECTD1,COPA,COG3,F11R,G3BP2,SUPT7L,RAN,FAM129A,TMEM33,TXNDC15,RNF4,DNAJC27,ARL6IP4,PCBD2,FNIP1,G2E3,BRMS1L,BRD8,GOLGA3,DOCK9,ZNF721,IGSF8,HMGCR,GUF1,IL6ST,FAM49A,LETM1,PABPN1" MicroRNA hsa-miR-876-3p:mirSVR_highEffct hsa-miR-876-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-12 2.26E-08 1.58E-11 1.44E-10 35 751 "MDM4,CDKL4,BLZF1,ARHGAP5,CD84,CCNA1,FCGR2C,ITGBL1,POU2F1,IL20,EIF2AK2,SPATA18,PARPBP,SETDB2,MBNL2,TCTN2,MAEA,FCGR3A,FCGR3B,GORAB,IVNS1ABP,NFASC,KLHL20,ZBTB37,BRD8,MAST4,ADAM17,MTUS2,FCRLA,RNF17,NPL,TECRL,KCNN2,RMST,ZNF304" MicroRNA hsa-miR-1197:mirSVR_highEffct hsa-miR-1197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.26E-12 2.26E-08 1.58E-11 1.44E-10 35 751 "AACS,RAB29,PNP,AMDHD1,FCHO2,DCLK1,RGSL1,PIK3C2B,TINF2,B3GLCT,RB1,ARGLU1,CWC27,DNAJC27,ADGRV1,IRF9,NDUFAF7,FOXO1,BRMS1L,NUBPL,UFM1,GFM2,THADA,TADA1,CCDC88A,C1orf112,NPAS3,PPARGC1A,SCFD1,TMPO,TMEM174,TPTE2,ZMYM2,DIAPH3,SPRYD7" MicroRNA hsa-miR-654-5p:mirSVR_lowEffct hsa-miR-654-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.30E-12 2.29E-08 1.59E-11 1.46E-10 54 1618 "LRRC43,ADD1,ACOX3,ATP1A2,CADM3,CD1D,CDK18,PDE6B,PKP1,SNCAIP,NR1I3,DNMT3A,ZNF329,RNASEL,MBNL2,TCTN2,FAM172A,STK32B,F7,F10,PCBD2,TMEM129,RELL1,POLK,PEAR1,STAB2,SH3BP2,DDX51,POTEM,C1orf112,PUS1,KIF21B,ATP8A2,NFASC,SRP72,RBKS,ANKLE2,C5orf56,TEP1,SLC7A8,AP4S1,NPL,ADAMTS19,RXFP2,FCRL6,C12orf73,ZBED3-AS1,KIF3C,KIR2DL1,KIR2DS4,KIR3DL1,EP400P1,AXDND1,CDK2AP1" MicroRNA hsa-miR-632:mirSVR_highEffct hsa-miR-632:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.46E-12 2.37E-08 1.65E-11 1.51E-10 34 712 "CUL4A,MSH2,ARL1,KCTD12,WDFY2,JAKMIP1,SNCAIP,CSNK1G3,VCAN,LRRTM2,FAM169A,MATR3,COG3,OCIAD1,RASA1,MEMO1,GUSBP3,DLEU1,ABCA11P,GORAB,PIBF1,SUCO,FLT1,VEZT,ALKAL2,ZNF605,GABRA2,CMPK2,ANKLE2,PPARGC1A,IGF1,NPHS2,LINC01913,SPRYD7" MicroRNA hsa-miR-4267:mirSVR_highEffct hsa-miR-4267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.57E-12 2.43E-08 1.69E-11 1.55E-10 31 596 "SEMA6A,CENPBD1P1,CBLN3,MPZL1,PCCA,PDGFRA,NGDN,SREK1,OGFOD2,NTN4,GUSBP3,DCUN1D2,MARVELD2,CWC27,ABCA11P,PCGF3,RUBCNL,UFM1,WDCP,RAPGEF6,DRC1,LPIN1,BRD8,METAP2,ANO4,TCF7,ARHGEF28,DOCK9,RIMBP2,TPO,TTC41P" MicroRNA hsa-miR-146b-5p:mirSVR_highEffct hsa-miR-146b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.60E-12 2.45E-08 1.70E-11 1.56E-10 42 1052 "MCC,KIAA1211,BLZF1,NCOA1,BTF3,RAB29,NOVA1,FCHO2,PDGFRA,CFL2,EPGN,LYSMD3,LRRTM2,MPHOSPH8,ZNF586,IFT172,BIVM,PTGS2,FAM129A,RNF31,RB1,PACRGL,TRAPPC12,SH3YL1,GORAB,PIBF1,RUBCNL,CCDC88A,MRPS27,SRP72,LRCH1,NMU,MTUS2,ADGRL3,EML4,DOCK9,ZNF550,PAPPA2,IL6ST,PLB1,KIR2DL4,AXDND1" MicroRNA hsa-miR-450b-5p:PITA hsa-miR-450b-5p:PITA_TOP PITA 4.98E-12 2.65E-08 1.84E-11 1.68E-10 31 598 "MAP1B,ARHGAP5,FCHO2,CFL2,PRKD1,SREK1,DMXL1,CEP350,CLIP4,MEMO1,NTN4,EIF2D,FAM172A,CWC27,FOXG1,FOXO1,NBEA,NR5A2,MYT1L,LRCH1,PCDH17,DHRS4,ADGRL3,EML4,DOCK9,XPO4,KLF12,UBE2K,IGF1,ZMYM2,TMEM178A" MicroRNA hsa-miR-1268:mirSVR_lowEffct hsa-miR-1268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.19E-12 2.76E-08 1.91E-11 1.75E-10 34 716 "KIAA1211,UVSSA,ZNF784,NOP14,AACS,KCTD12,NEDD8,NRL,SCARB1,FCRLB,CDK18,PDE6B,ZNF595,EPGN,FCRL5,SLC35F6,FAM228A,POLR1D,RNF4,TCTN2,STK32B,F7,IRF9,NUBPL,UFM1,SLC30A6,JPH4,ATP8A2,COX18,TEP1,RASSF6,HEXB,KCNN2,TTC7A" MicroRNA hsa-miR-128-3p:TargetScan hsa-miR-128-3p TargetScan 5.31E-12 2.82E-08 1.96E-11 1.79E-10 38 882 "ABL2,MATN3,MDM4,NLN,PITPNM2,FBRSL1,NCOA1,NOVA1,PCDH9,FAM177A1,CDK18,PDGFRA,NRXN1,HECTD1,POU2F1,LYSMD3,ITSN2,CEP135,PRKD1,FAM129A,SBNO1,FAM172A,PCGF3,CCDC92,CCDC88A,POTEM,NR5A2,GABRB1,PDS5B,NPAS3,NFASC,PPARGC1A,GJA3,CNTN2,DCP2,IGF1,LMNB1,LOX" MicroRNA hsa-miR-512-5p:mirSVR_highEffct hsa-miR-512-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.35E-12 2.84E-08 1.97E-11 1.80E-10 32 638 "MCFD2,DHX37,PPP1R12B,BCL2L2,PCSK1,RCBTB2,THTPA,VCAN,LRRTM2,SNX17,COG3,CEP350,PARPBP,LAP3,ELF1,TRAPPC13,FCGR3A,PIBF1,MROH9,FMO1,UFM1,TADA1,DRC1,LRCH1,ARHGEF28,TDG,TFDP1,GZMB,WDR36,ZBED3-AS1,FIP1L1,LMNB1" MicroRNA hsa-miR-505*:mirSVR_highEffct hsa-miR-505*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.80E-12 3.08E-08 2.13E-11 1.95E-10 32 640 "RALGAPA1,KIAA1211,APC,MYH6,NEDD8,NFATC4,CDKL2,LDB2,SCFD2,LINC01085,STRN3,DCAF8,PIGG,G3BP2,C14orf119,EIF2D,TCTN2,FCAR,TMEM132D,DCAF11,CIDEB,JPH4,NAAA,ERAP1,SRP72,NEDD1,LRCH1,MIMT1,PSME4,GPR12,UBE2K,RXFP2" MicroRNA hsa-miR-32-5p:Functional MTI Functional MTI miRTarbase 6.07E-12 3.23E-08 2.23E-11 2.04E-10 30 565 "MAP1B,ATP2B4,CAD,FCHO2,CCNB1,XPR1,HECTD1,COG3,F11R,G3BP2,SUPT7L,FAM129A,ARGLU1,TMEM33,TXNDC15,RNF4,DNAJC27,PCBD2,FNIP1,G2E3,BRMS1L,ERBIN,GOLGA3,DOCK9,ZNF721,HMGCR,GUF1,IL6ST,FAM49A,LETM1" MicroRNA hsa-miR-645:mirSVR_lowEffct hsa-miR-645:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.72E-12 3.57E-08 2.47E-11 2.26E-10 41 1020 "TBC1D14,WDR35,APC,MSH2,BTF3,RAB29,MPZL1,UHMK1,SNTG2,SLC5A8,GLT1D1,ITGBL1,TM9SF2,POLE,SNCAIP,CSNK1G3,PRKD1,BIVM,PTGS2,LOC439933,PPP2R3C,NR1I3,EGLN3,RNF31,MEMO1,EFNA5,SAP18,SULT6B1,STPG4,PKD2L2,SLC22A5,MCCC2,ADGRA3,TCF7,NCSTN,YTHDC2,ZMYM2,NUAK2,AXDND1,IFT88,MICU2" MicroRNA hsa-miR-1225-5p:mirSVR_highEffct hsa-miR-1225-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.83E-12 3.63E-08 2.51E-11 2.30E-10 25 391 "SMIM15,MPZL1,CCDC122,THAP6,FCRL5,KLHL3,RNF219,NR1H4,RB1,NTN4,RNASEL,FAM172A,CWC27,ETF1,SUPT20H,UFM1,STPG4,MEGF10,TMEM183A,IQGAP2,IKBIP,PSME4,TEP1,ZMYM2,ZBED3-AS1" MicroRNA hsa-miR-4269:mirSVR_highEffct hsa-miR-4269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.28E-12 3.87E-08 2.67E-11 2.45E-10 34 725 "COG6,BLZF1,FCRL3,CAST,PCSK1,PDGFRA,GPR180,SMIM14,AKAP6,CSNK1G3,ZFYVE16,COG3,PPP2R3C,SNORA49,SAP18,ETF1,ADGRV1,PIBF1,SUCO,FOXO1,STAB2,PKD2L2,GJB6,DRC1,ATP11A,TFDP1,HAL,TENT2,ZNF10,IL6ST,ZMYM2,CHPT1,FAM71C,LOX" MicroRNA hsa-miR-1308:mirSVR_highEffct hsa-miR-1308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.55E-12 4.02E-08 2.77E-11 2.54E-10 30 570 "WDR35,SNX24,AACS,NCOA1,CAST,CD1E,PDGFRA,GPR180,TAPT1,GNPTAB,PRKD1,DHFR,CLIP4,MEMO1,NTN4,EFNA5,TMEM156,POLK,SELP,CCDC88A,GABRA2,RAPGEF6,DRC1,PPARGC1A,METAP2,MTUS2,BAZ1A,SLAIN1,AXDND1,CDK2AP1" MicroRNA hsa-miR-10a:mirSVR_highEffct hsa-miR-10a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.58E-12 4.03E-08 2.78E-11 2.54E-10 31 608 "KIAA1211,COG6,ARL1,STARD13,CCNA1,DAOA,CENPC,ZNF595,GPR180,LYSMD3,NCOR2,TMEM161B,FAM172A,ARSK,STK32B,SDC1,UFM1,CCDC88A,NR5A2,ZNF667,TMEM183A,HSPH1,NPAS3,PSME4,GOLGA3,C1QTNF9B,LINC01551,BAZ1A,HMGCR,SLAIN1,RMST" MicroRNA hsa-miR-335:PITA hsa-miR-335:PITA_TOP PITA 7.60E-12 4.04E-08 2.78E-11 2.55E-10 18 187 "ATP6V1G3,SLC4A4,BCL2L2,PCDH9,NRXN1,STRN3,CEP350,RASA1,RB1,ARGLU1,ETF1,CHFR,NMNAT2,KMT5A,COP1,ADAMTS19,HMGCR,SPTSSA" MicroRNA hsa-miR-376c:PITA hsa-miR-376c:PITA_TOP PITA 7.66E-12 4.07E-08 2.80E-11 2.57E-10 22 298 "MAP1B,NCOA1,ATP2B4,FCHO2,ATAD2B,BOD1L1,CLOCK,DNM3,RNF219,NTN4,FLT3,VEZT,SLC8A1,NR5A2,MEGF10,KDM5B,ERBIN,ADGRL3,BAZ1A,RIMBP2,KLF12,ZMYM2" MicroRNA hsa-miR-130b-3p:Functional MTI Functional MTI miRTarbase 7.88E-12 4.19E-08 2.88E-11 2.64E-10 30 571 "MCC,ARL1,STARD13,PDGFRA,CFL2,THAP6,GNPTAB,C12orf65,UBXN2A,DCAF8,PIGG,FBXL5,RAN,EGLN3,FAM129A,RB1,MPHOSPH9,CLIP1,FAM114A1,ERBIN,PPARGC1A,GRSF1,GPR161,HSP90B1,UBC,SLAIN1,TENT2,IGF1,IRF1,LMLN" MicroRNA hsa-miR-98:mirSVR_highEffct hsa-miR-98:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.36E-12 4.44E-08 3.05E-11 2.80E-10 36 811 "MDM4,SLAMF6,HOMEZ,BLZF1,SLC4A4,SLC5A6,NOVA1,ITGBL1,SNX6,PTPRVP,GNPTAB,POU2F1,CEP135,KLHL3,CEP120,PTPRC,PARPBP,ATG10,RNF31,RGS12,CWC27,PCGF3,FCGR2B,NDUFAF7,GORAB,FNIP1,SUCO,VEZT,GABRA2,HSPH1,ACSL6,CRB1,PAPPA2,ZNF10,SPRYD7,AXDND1" MicroRNA hsa-miR-490-3p:mirSVR_highEffct hsa-miR-490-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.47E-12 4.50E-08 3.09E-11 2.83E-10 28 499 "ZNF784,CD84,TAF1B,CHAMP1,CD1D,SNTG2,PDE4D,PDGFRA,CHD1,VIT,POU2F1,ZFYVE16,FBXL5,NUDT12,RABGAP1L,NR1I3,DNMT3A,REST,TBC1D19,PIBF1,VEZT,STPG4,GABRB1,PCDH17,ZNF544,UTP20,TMED2,CDK2AP1" MicroRNA hsa-miR-532-5p:mirSVR_highEffct hsa-miR-532-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.55E-12 4.55E-08 3.12E-11 2.86E-10 41 1028 "KIAA1211,MIPEP,STXBP6,CENPBD1P1,ARHGEF7,NOVA1,CAST,FCHO2,PAH,NFXL1,PCDH9,PCSK1,PFKFB2,CLOCK,DHX9,DHFR,PACRGL,LGR6,TBC1D19,CWC27,DNAJC27,ABCA11P,PCGF3,TMEM156,FGF9,SUCO,FMO1,NBEA,BRMS1L,SLC8A1,CCDC88A,MRPS14,NR5A2,PDS5B,NPAS3,STON1,ZBTB49,RASSF6,IL6ST,CCDC169,FAM151B" MicroRNA hsa-miR-3198:mirSVR_highEffct hsa-miR-3198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.01E-12 4.79E-08 3.29E-11 3.01E-10 32 651 "ADCY4,APC,ZNF784,BLZF1,NFATC4,SCFD2,CHIT1,CPNE6,LTB4R,STRN3,HEATR5A,SNCAIP,LACC1,VCAN,UBXN2A,CEP350,RNF31,RASA1,RB1,EIF2D,GORAB,FGF9,KDM5B,FAM114A1,ERAP1,KDM3B,DOCK9,CRB1,TMPO,GPN1,GUF1,LINC01913" MicroRNA hsa-miR-4459:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.18E-12 4.88E-08 3.34E-11 3.06E-10 33 691 "MDM4,MMP17,APAF1,NOP14,PIK3C2B,GNPTAB,EPGN,NCOR2,MPHOSPH8,EIF2AK2,MTX3,ZNF329,DTD2,RGS12,TMEM33,POLR1D,TCTN2,TBC1D19,CCDC38,FNIP1,BRMS1L,PLEKHA6,KIF21B,SNRNP35,GRSF1,ZBTB49,ATP6V0A2,HSP90B1,GUF1,IGF1,ZNF324B,PGAM5,PABPN1" MicroRNA hsa-miR-1202:mirSVR_highEffct hsa-miR-1202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.51E-12 5.06E-08 3.46E-11 3.17E-10 29 538 "WDR19,UHMK1,BIVM,FBXL5,NUDT12,RABGAP1L,TSEN15,AASDH,MEMO1,ZNF419,DRAM1,ABCA11P,ADGRV1,FLT1,G2E3,ARHGEF40,NAAA,ERAP1,PCDH17,EML4,ADAMTS19,HPCAL1,HTR2A,KCNT2,IL6ST,CCDC190,SLAMF9,AXDND1,LMNB1" MicroRNA hsa-miR-204:PITA hsa-miR-204:PITA_TOP PITA 9.53E-12 5.07E-08 3.47E-11 3.18E-10 26 431 "ABL2,SEMA6A,ARHGAP5,BCL2L2,NOVA1,PCDH9,ATAD2B,HEATR5A,DCAF8,CLIP4,LATS2,ETF1,CLIP1,FNIP1,SUCO,FLT3,VEZT,NBEA,MEGF10,MYT1L,HSPH1,ERBIN,PPARGC1A,KMT5A,XPO4,KLF12" MicroRNA hsa-miR-211:PITA hsa-miR-211:PITA_TOP PITA 9.53E-12 5.07E-08 3.47E-11 3.18E-10 26 431 "ABL2,SEMA6A,ARHGAP5,BCL2L2,NOVA1,PCDH9,ATAD2B,HEATR5A,DCAF8,CLIP4,LATS2,ETF1,CLIP1,FNIP1,SUCO,FLT3,VEZT,NBEA,MEGF10,MYT1L,HSPH1,ERBIN,PPARGC1A,KMT5A,XPO4,KLF12" MicroRNA hsa-miR-644:mirSVR_highEffct hsa-miR-644:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.77E-12 5.20E-08 3.55E-11 3.25E-10 30 576 "MAP1B,NLN,UVSSA,BCL2L2,PDE4D,PDE6B,UBXN2A,DHFR,ZNF419,GRTP1,KIRREL1,MPHOSPH9,ARSK,PCGF3,F10,TOMM40L,FTLP10,CCDC92,PAICS,ZNF446,WDCP,C1orf112,NFASC,DRC1,COMMD6,LPIN1,COP1,NCSTN,TNNT2,CCDC169" MicroRNA hsa-miR-522:PITA hsa-miR-522:PITA_TOP PITA 1.02E-11 5.43E-08 3.71E-11 3.39E-10 28 503 "ARHGAP5,ASCL1,CDK17,PDGFRA,ATAD2B,HOMER1,AKAP6,RASA1,EFNA5,ETF1,FNIP1,RELL1,SUCO,ZCCHC8,NBEA,SLC12A2,NMNAT2,HSPH1,KDM3B,PCDH17,PPARGC1A,INSM2,ATP11A,UBE2K,HTR2A,NSD2,KCNT2,KIT" MicroRNA hsa-miR-550*:mirSVR_highEffct hsa-miR-550*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-11 5.43E-08 3.71E-11 3.39E-10 28 503 "MAP1B,ATP1A2,PDE4D,THAP6,SYCP3,CRHBP,VCAN,DMXL1,DHFR,GUSBP3,SNORA49,LGR6,CCDC38,UTP15,NUBPL,MYT1L,NAAA,NPAS3,LRCH1,IKBIP,PCDH17,RIPK3,DOCK9,CRB1,TMPO,C12orf73,KCNN2,KIF2A" MicroRNA hsa-miR-3176:mirSVR_highEffct hsa-miR-3176:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-11 5.78E-08 3.94E-11 3.61E-10 29 541 "CENPBD1P1,SMIM14,NUP37,LTB4R,THAP6,TAPT1,RABGAP1L,RNF219,DNMT3A,GALNT14,B3GLCT,POLR1D,SETDB2,GUSBP3,FAM172A,CLIP1,GORAB,FGF9,POLK,CGREF1,CYP1B1-AS1,NPAS3,ERBIN,ZBTB37,ADGRL3,MAEL,HSD17B4,IFT88,LOX" MicroRNA hsa-miR-155-5p:Functional MTI Functional MTI miRTarbase 1.09E-11 5.80E-08 3.96E-11 3.62E-10 38 904 "TBC1D14,HOMEZ,APAF1,APC,MSH2,NOVA1,MPZL1,PCCA,PCDH9,FAM177A1,XPR1,CFL2,SNX6,STRN3,TAPT1,BRI3BP,TTC37,MATR3,ARGLU1,TMEM33,DCUN1D2,FCAMR,FLT1,HSD17B7,MRPS27,ERBIN,IKBIP,STRN,PSME4,METAP2,KMT5A,MSH6,HAL,JCHAIN,TADA2B,FIP1L1,CAB39L,DIAPH3" MicroRNA hsa-miR-146a:mirSVR_highEffct hsa-miR-146a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.12E-11 5.95E-08 4.05E-11 3.71E-10 41 1037 "MCC,KIAA1211,BLZF1,AACS,NCOA1,BTF3,RAB29,NOVA1,FCHO2,PDGFRA,CFL2,EPGN,LYSMD3,LRRTM2,MPHOSPH8,ZNF586,BIVM,PTGS2,FAM129A,RNF31,RB1,PACRGL,TRAPPC12,SH3YL1,GORAB,PIBF1,RUBCNL,CCDC88A,NR5A2,MRPS27,SRP72,LRCH1,MTUS2,ADGRL3,EML4,DOCK9,ZNF550,PAPPA2,PLB1,KIR2DL4,AXDND1" MicroRNA hsa-miR-155:PITA hsa-miR-155:PITA_TOP PITA 1.13E-11 6.02E-08 4.10E-11 3.75E-10 22 304 "ABL2,ASTN1,NOVA1,ZNF664,PCDH9,ATAD2B,STRN3,TAPT1,LRRTM2,CEP350,G3BP2,TMEM33,MBNL2,MPHOSPH9,FBXO11,G2E3,KDM5B,TMED2,KHNYN,IGF1,ZNF470,ZMYM2" MicroRNA hsa-miR-562:PITA hsa-miR-562:PITA_TOP PITA 1.18E-11 6.26E-08 4.26E-11 3.90E-10 17 167 "MCC,FAM193A,NCOA1,PPP1R12B,XPR1,CHD1,NRXN1,HECTD1,MATR3,DEPDC4,FOXO1,SLC12A2,MYO16,PPARGC1A,UBE2K,IGF1,ZBTB41" MicroRNA hsa-miR-1185:mirSVR_highEffct hsa-miR-1185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-11 6.37E-08 4.33E-11 3.96E-10 33 698 "ABL2,WDR19,NEDD8,MPZL1,THAP6,STRN3,SNCAIP,ZNF586,DMXL1,TBC1D4,TINF2,B3GLCT,RGS4,DHRS2,TLR6,TRAPPC13,GORAB,ZNF605,SLC12A2,CGREF1,MYO16,PDS5B,NAAA,LRCH1,ADGRA3,COX18,RAB2B,GUF1,PAPPA2,ZNF10,IL6ST,PLB1,CHPT1" MicroRNA hsa-miR-612:mirSVR_highEffct hsa-miR-612:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-11 6.64E-08 4.51E-11 4.13E-10 40 996 "MCC,MYBPC1,STARD13,NEDD8,FCRL3,CAST,SLC5A8,ZNF595,FAM163A,CSNK1G3,SNX17,PXMP2,PPP2R3C,RASA1,RGS4,RGS12,PACRGL,BORA,CLIP1,TNFRSF19,PIBF1,FMO1,GOLGA2P5,TMEM175,CCDC92,PKD2L2,NR5A2,CYP1B1-AS1,PDS5B,TMEM183A,ZNF274,MCCC2,GJB2,ADAM17,NCSTN,ZNF26,IL6ST,LINC01913,LMNB1,CDK2AP1" MicroRNA hsa-miR-603:Functional MTI Functional MTI miRTarbase 1.29E-11 6.84E-08 4.65E-11 4.25E-10 28 508 "SMIM15,SYT2,FAM177A1,CFL2,ITGBL1,NUP37,BRI3BP,CEP135,SREK1,DMXL1,KLHL3,ATG10,FGF9,BRMS1L,SLC12A2,SLC22A4,LILRB1,PPARGC1A,STRN,RASSF6,TECRL,NLRP8,DCP2,IGF1,IL6ST,CCDC169,ZMYM2,SPATA13" MicroRNA hsa-miR-1260b:mirSVR_highEffct hsa-miR-1260b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-11 6.87E-08 4.66E-11 4.27E-10 31 621 "ACOX3,B4GALT3,NEDD8,BTF3,CDKL2,CD1D,WDFY2,CFAP54,HECTD1,RNASE9,THTPA,ZFYVE16,LINC01257,DNMT3A,FAM228A,RGS12,STX2,F7,FNIP1,SUCO,FLT3,UFM1,IQGAP2,KDM3B,NEDD1,TCF7,TNR,TECRL,GUF1,IL6ST,PABPN1" MicroRNA hsa-miR-646:PITA hsa-miR-646:PITA_TOP PITA 1.30E-11 6.89E-08 4.67E-11 4.27E-10 26 437 "RALGAPA1,MCC,ARHGAP5,BTF3,NOVA1,CAD,ODC1,DCLK1,PDGFRA,HECTD1,AKAP6,PRKD1,SREK1,CEP350,F11R,G3BP2,LATS2,G2E3,NBEA,MYT1L,KIF21B,PPARGC1A,STRN,XPO4,KIF2A,PABPN1" MicroRNA hsa-miR-29a:PITA hsa-miR-29a:PITA_TOP PITA 1.32E-11 7.00E-08 4.73E-11 4.33E-10 30 583 "SFTA3,BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,SLC5A8,ATAD2B,STRN3,NCOR2,DNM3,DNMT3A,POLR1D,KIRREL1,PCGF3,CHFR,MYO16,KDM5B,ERBIN,PCDH17,PPARGC1A,PSME4,EML4,KMT5C,TDG,ADAMTS19,HMGCR,DCP2,IGF1,ZBTB41" MicroRNA hsa-miR-29c:PITA hsa-miR-29c:PITA_TOP PITA 1.32E-11 7.00E-08 4.73E-11 4.33E-10 30 583 "SFTA3,BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,SLC5A8,ATAD2B,STRN3,NCOR2,DNM3,DNMT3A,POLR1D,KIRREL1,PCGF3,CHFR,MYO16,KDM5B,ERBIN,PCDH17,PPARGC1A,PSME4,EML4,KMT5C,TDG,ADAMTS19,HMGCR,DCP2,IGF1,ZBTB41" MicroRNA hsa-miR-29b:PITA hsa-miR-29b:PITA_TOP PITA 1.32E-11 7.00E-08 4.73E-11 4.33E-10 30 583 "SFTA3,BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,SLC5A8,ATAD2B,STRN3,NCOR2,DNM3,DNMT3A,POLR1D,KIRREL1,PCGF3,CHFR,MYO16,KDM5B,ERBIN,PCDH17,PPARGC1A,PSME4,EML4,KMT5C,TDG,ADAMTS19,HMGCR,DCP2,IGF1,ZBTB41" MicroRNA hsa-miR-448:TargetScan hsa-miR-448 TargetScan 1.35E-11 7.17E-08 4.85E-11 4.44E-10 28 509 "ADD1,APBB2,APC,PPP1R12B,DCLK1,FAM177A1,PDE4D,CFL2,ATAD2B,HOMER1,KLHL3,RASA1,REST,MBNL2,N4BP2L2,NBEA,BRMS1L,PLEKHA6,ARHGEF40,NMNAT2,NPAS3,NFASC,ATP11A,ACSL6,DOCK9,RAB2B,DCP2,KIF2A" MicroRNA hsa-miR-455-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-11 7.41E-08 5.01E-11 4.59E-10 35 784 "MAP1B,HOMEZ,DDX55,PPP1R12B,BTF3,CAD,RILPL1,CCNB1,XPR1,PDGFRA,GNPTAB,MPHOSPH8,FCRL2,F11R,MTX3,SUPT7L,TMEM33,TXNDC15,SBNO1,MARVELD2,TCTN2,STX2,MAEA,CCDC38,FNIP1,N4BP2L2,BRMS1L,MRPS14,KIF21B,COX18,ATP6V0A2,HSP90B1,GUF1,IGF1,C12orf73" MicroRNA hsa-miR-330-5p:mirSVR_highEffct hsa-miR-330-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.41E-11 7.50E-08 5.06E-11 4.63E-10 34 743 "RALGAPA1,TAF1B,FCRLB,PDGFRA,RCBTB2,ITGBL1,LINC01085,ATAD2B,THAP6,AKAP6,DNM3,SNX17,LINC01257,DNMT3A,TOMM40L,FGF9,TNFRSF19,VEZT,SLC22A4,CYP1B1-AS1,ZNF274,CD244,NPAS3,MCCC2,ERBIN,ZNF544,ADAM17,CRB1,ZBTB49,SLAIN1,ZNF876P,ZFHX2,ZNF470,SLAMF9" MicroRNA hsa-miR-500b:mirSVR_highEffct hsa-miR-500b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-11 7.76E-08 5.23E-11 4.79E-10 31 624 "SNX24,CDKL2,CAST,UHMK1,GPR180,PIK3C2B,JAKMIP1,THAP6,AKAP6,STRN3,UBXN2A,ZFYVE16,OCIAD1,RABGAP1L,ADGRV1,NDUFAF7,TADA1,ZNF605,RAPGEF6,HSPH1,KLHL20,UGT2A1,ANO4,TPO,UBE2K,GUF1,IGF1,KCNT2,SLAMF9,RMST,LTA4H" MicroRNA hsa-miR-31:mirSVR_highEffct hsa-miR-31:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.47E-11 7.79E-08 5.25E-11 4.81E-10 37 870 "STARD13,MYH6,GLT1D1,HOMER1,PREPL,LRRTM2,FCRL2,DCAF8,OCIAD1,G3BP2,EGLN3,RASA1,TMEM161B,SMC6,RGS4,LATS2,RNF4,DEPDC4,N4BP2L2,POLK,VEZT,ARHGEF40,SLC15A4,C1orf112,FSHR,NR5A2,GABRA2,MYT1L,MTUS2,RNF17,TEP1,CRB1,GUF1,PAPPA2,IRF1,DIAPH3,AXDND1" MicroRNA hsa-miR-4264:mirSVR_highEffct hsa-miR-4264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-11 7.86E-08 5.30E-11 4.85E-10 29 548 "CDKL4,PPP1R12B,NFXL1,CDK17,RGSL1,WDFY2,AKAP6,BRI3BP,ZFYVE16,SNX17,TINF2,G3BP2,NR1H4,FAM129A,PACRGL,KLHL12,CWC27,VEZT,ZCCHC8,SCYL2,THADA,TADA1,WDCP,CYP1B1-AS1,ACSL6,DCP2,ZNF10,KIF2A,SKA3" MicroRNA hsa-miR-4284:mirSVR_highEffct hsa-miR-4284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-11 8.69E-08 5.85E-11 5.36E-10 27 477 "RALGAPA1,MATN3,NLN,NOP14,SCARB1,UHMK1,CDK17,ZNF595,JAKMIP1,AASDH,EIF2B1,PCBD2,N4BP2L2,HSD17B7,TM9SF1,RUBCNL,NUBPL,LILRB1,STRN,UTP20,COP1,TGFBI,NPL,STARD4,ZNF470,IFT88,PABPN1" MicroRNA hsa-miR-675*:mirSVR_highEffct hsa-miR-675*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.68E-11 8.96E-08 6.03E-11 5.52E-10 29 551 "MDM4,KIAA1211,APC,AP1G2,CAMK4,UHMK1,SNX6,GNPTAB,VCAN,SREK1,RGS4,CLIP4,ELF1,CWC27,TOMM40L,N4BP2L2,TNFRSF19,SUCO,TMEM183A,NEDD1,TMED2,KMT5A,ADAMTS19,FCRL6,ZFHX2,IL6ST,CCDC169,ZBED3-AS1,NUAK2" MicroRNA hsa-miR-3137:mirSVR_highEffct hsa-miR-3137:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-11 9.67E-08 6.50E-11 5.95E-10 32 669 "SMIM15,KIAA1211,MIPEP,APC,CAST,ZMYM5,CDK18,GPR180,ATAD2B,PREPL,PARPBP,CLIP4,TXNDC15,LGR6,N4BP2L2,SUCO,FLT1,FBXO11,ZNF605,N4BP2,MYT1L,KIF21B,PDS5B,DRC1,MAST4,ANO4,BAZ1A,TPO,TENT2,IL6ST,ZBED3-AS1,ZNF304" MicroRNA hsa-miR-597:mirSVR_highEffct hsa-miR-597:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-11 1.00E-07 6.73E-11 6.17E-10 27 480 "CENPBD1P1,SLC5A6,CACNA1E,CAST,CFL2,BOD1L1,ADGRF3,RCHY1,G3BP2,RNASEL,UGT2A3,MARVELD2,FTLP10,VEZT,PDS5B,SRP72,MAEL,SLAIN1,FCRL6,IL6ST,IRF1,LHX9,NPHS2,TMEM178A,FIP1L1,LCP1,PABPN1" MicroRNA hsa-miR-4305:mirSVR_lowEffct hsa-miR-4305:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.92E-11 1.02E-07 6.84E-11 6.26E-10 42 1101 "MATN3,COG6,RGS5,ARL1,NFATC4,MPZL1,PDGFRA,SLC25A3,LTB4R,RCHY1,DNM3,BIVM,PTGS2,GNPDA2,RAN,RB1,AASDH,GUSBP3,PACRGL,ELK3,DHRS2,PAICS,WDCP,PDS5B,CENPJ,ATP8A2,NPAS3,COMMD6,MAST4,METAP2,GPR12,GTF2H3,FZD10,NPL,ADAMTS19,GUF1,SPTSSA,LHX9,KIF2A,KIR3DL1,AXDND1,ZNF304" MicroRNA hsa-miR-1260:mirSVR_highEffct hsa-miR-1260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-11 1.03E-07 6.89E-11 6.30E-10 31 631 "ACOX3,NEDD8,BTF3,CDKL2,CD1D,WDFY2,CFAP54,HECTD1,RNASE9,ZFYVE16,LINC01257,DNMT3A,FAM228A,RGS12,STX2,F7,FNIP1,N4BP2L2,SUCO,MROH9,FLT3,UFM1,IQGAP2,KDM3B,NEDD1,TCF7,TNR,TECRL,GUF1,IL6ST,PABPN1" MicroRNA hsa-miR-218-1*:mirSVR_highEffct hsa-miR-218-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-11 1.11E-07 7.46E-11 6.83E-10 33 713 "HOMEZ,CDKL4,CHAMP1,CDK17,CFAP54,NGDN,NCOR2,LRRTM2,DNM3,DTD2,ETF1,F10,TMEM156,FNIP1,PEAR1,MROH9,FOXO1,SLC12A2,TMEM183A,KDM3B,ADGRL3,ADGRA3,LINC01551,AP4S1,FZD10,HTR2A,GALP,ZMYM2,FAM151B,RPGRIP1,TTC41P,SPRYD7,PABPN1" MicroRNA hsa-miR-145*:mirSVR_highEffct hsa-miR-145*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-11 1.13E-07 7.55E-11 6.91E-10 39 969 "NDRG2,CDKL4,AACS,NCOA1,CD84,DAOA,PDGFRA,WDFY2,LYSMD3,TTC37,FCRL2,KLHL3,PTPRC,TINF2,G3BP2,SUPT7L,TSEN15,AASDH,NTN4,LATS2,MPHOSPH9,ARSK,DNAJC27,ELOVL7,FCGR3A,FCGR3B,IVNS1ABP,CCDC88A,MYO16,GABRA2,ERAP1,MCCC2,PPARGC1A,TMED2,TCF7,HAL,GUF1,LINC00272,LCP1" MicroRNA hsa-miR-486-5p:mirSVR_highEffct hsa-miR-486-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.13E-11 1.13E-07 7.60E-11 6.96E-10 26 447 "BIRC6,UVSSA,ARHGAP5,ARL1,CCNA1,PTPRVP,DHFR,NR1H4,DNMT3A,RGS4,FAM81B,UTP15,FGF9,FOXO1,FTLP10,SCYL2,CIDEB,PDS5B,CENPJ,MCCC2,IKBIP,METAP2,GOLGA3,ADAMTS19,SLAIN1,AXDND1" MicroRNA hsa-miR-215-5p:Functional MTI Functional MTI miRTarbase 2.16E-11 1.15E-07 7.70E-11 7.05E-10 34 755 "MDM4,APC,KCTD12,GAS2L3,CAMK4,MPZL1,CFL2,GPR180,POU2F1,C12orf65,BIVM,COCH,RNF219,ATG10,RB1,CLIP4,RNASEL,BORA,G2E3,ARHGEF40,TNFSF13B,WDCP,C1orf112,NEDD1,NMU,TCF7,TDG,MSH6,TMPO,UBE2K,NSD2,IL6ST,CHPT1,LMNB1" MicroRNA hsa-miR-106a-5p:Functional MTI Functional MTI miRTarbase 2.17E-11 1.15E-07 7.71E-11 7.06E-10 33 714 "MCC,ULK1,CUL4A,APC,ARHGAP5,BCL2L2,FCHO2,CFL2,PFKFB2,GNPTAB,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,RABGAP1L,SLC35F6,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,N4BP2L2,SUCO,ZNF446,ZBTB37,GTF2H3,TXK,UBC,ZDHHC20" MicroRNA hsa-miR-1273:mirSVR_lowEffct hsa-miR-1273:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-11 1.15E-07 7.71E-11 7.06E-10 27 483 "UVSSA,NEDD8,CHAMP1,RCBTB2,ITGBL1,HECTD1,UBXN2A,FCRL5,SPATA18,NUDT12,TBC1D4,C14orf119,DTD2,RNASEL,UGT2A3,MPHOSPH9,GP6,FOXO1,FTLP10,THADA,GABRB1,FAM114A1,LRCH1,MAST4,FCRLA,TECRL,ANKS1B" MicroRNA hsa-miR-4265:mirSVR_highEffct hsa-miR-4265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-11 1.19E-07 7.96E-11 7.29E-10 26 448 "MDM4,APC,SNCAIP,PTGS2,PTPRC,RGS4,TXNDC15,RNF4,TRAPPC12,POLK,FOXO1,ZNF605,MEGF10,PDS5B,PCDH17,BRD8,MSH6,GTF3C2,ZNF10,LINC00272,KIR2DL4,KIR2DS4,KIR3DL1,KIR3DL2,AXDND1,SPATA13" MicroRNA hsa-miR-2277:mirSVR_lowEffct hsa-miR-2277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-11 1.20E-07 8.02E-11 7.34E-10 31 635 "LRRC43,HOMEZ,AACS,KCTD12,ADGRD1,CBLN3,ZNF595,HECTD1,TAPT1,BRI3BP,SPATA18,NR1I3,AASDH,FAM228A,MARVELD2,TBC1D19,TACC3,C1orf112,SLC22A4,YPEL5,GABRA2,ZNF544,DOCK9,RNF17,GZMB,RIMBP2,IGSF8,IL6ST,ZMYM2,CAB39L,ZDHHC20" MicroRNA hsa-miR-125a-3p:PITA hsa-miR-125a-3p:PITA_TOP PITA 2.28E-11 1.21E-07 8.08E-11 7.40E-10 17 174 "MAP1B,MCFD2,LDB2,CFL2,ATAD2B,F11R,G3BP2,ARGLU1,RGS4,TMEM129,SLC8A1,CHFR,MYT1L,KLHL20,KHNYN,ADAMTS19,KIF2A" MicroRNA hsa-miR-593:mirSVR_highEffct hsa-miR-593:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.31E-11 1.23E-07 8.18E-11 7.49E-10 36 841 "MAP1B,MCC,WDR35,HOMEZ,BTF3,PNP,CACNA1E,CAST,FCHO2,CDK18,HECTD1,HOMER1,AKAP6,LACC1,C12orf65,DNM3,UBXN2A,OCIAD1,PARPBP,NDUFAF7,PIBF1,VEZT,SCYL2,SLC22A4,CHFR,ERBIN,METAP2,ANO4,TCF7,TGFBI,TNR,SLAIN1,KCNT2,ZMYM2,FIP1L1,LETM1" MicroRNA hsa-miR-92b:PITA hsa-miR-92b:PITA_TOP PITA 2.61E-11 1.39E-07 9.24E-11 8.46E-10 27 487 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,CEP350,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-92a:PITA hsa-miR-92a:PITA_TOP PITA 2.61E-11 1.39E-07 9.24E-11 8.46E-10 27 487 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,CEP350,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-25:PITA hsa-miR-25:PITA_TOP PITA 2.61E-11 1.39E-07 9.24E-11 8.46E-10 27 487 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,CEP350,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-367:PITA hsa-miR-367:PITA_TOP PITA 2.61E-11 1.39E-07 9.24E-11 8.46E-10 27 487 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,CEP350,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-802:PITA hsa-miR-802:PITA_TOP PITA 2.72E-11 1.45E-07 9.62E-11 8.81E-10 26 452 "HOMEZ,APC,PCDH9,CFL2,CHD1,SMIM14,HECTD1,STRN3,BIVM,PTGS2,CEP350,G3BP2,RAN,RB1,LATS2,MBNL2,FAM172A,TMEM129,SLC8A1,IQGAP2,TBC1D1,ADGRL3,KLF12,SLAIN1,ZBTB41,LHX9" MicroRNA hsa-miR-503:mirSVR_lowEffct hsa-miR-503:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.81E-11 1.49E-07 9.92E-11 9.08E-10 38 934 "RALGAPA1,TMEM132B,MCFD2,APC,CCDC181,BTF3,CAST,CDK17,CFAP45,JAKMIP1,HECTD1,IL20,EPS8L1,COG3,CEP350,F11R,RABGAP1L,TSEN15,NR1I3,CLIP4,LATS2,GRTP1,RUBCNL,UGGT2,MYO16,ERAP1,BRD8,COP1,CRB1,FZD10,HAL,ADAMTS19,NLRP8,WDR36,NSD2,ZMYM2,KIF2A,LMNB1" MicroRNA hsa-miR-139-5p:PITA hsa-miR-139-5p:PITA_TOP PITA 2.89E-11 1.54E-07 1.02E-10 9.34E-10 22 319 "NDRG2,FCHO2,UHMK1,ZNF664,PDE4D,PGGT1B,SLC25A3,LYSMD3,DNM3,CEP350,MBNL2,TMEM132D,NR5A2,CHFR,KDM3B,ERBIN,PPARGC1A,PSME4,KMT5A,XPO4,GRSF1,TENT2" MicroRNA hsa-miR-147:mirSVR_highEffct hsa-miR-147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-11 1.60E-07 1.06E-10 9.71E-10 33 723 "ATP7B,FCRL3,PNP,CDKL2,CAST,LDB2,RGSL1,VIT,ATAD2B,AKAP6,POU2F1,SNCAIP,DCAF8,FBXL5,DNMT3A,LATS2,UGT2A3,LGR6,FCGR2B,TNFRSF19,RUBCNL,STPG4,WDCP,JPH4,TMEM183A,ERAP1,IKBIP,MAEL,TPO,ADAMTS19,ZFHX2,IL6ST,ZNF304" MicroRNA hsa-miR-489-3p:TargetScan hsa-miR-489-3p TargetScan 3.17E-11 1.69E-07 1.12E-10 1.02E-09 19 231 "BIRC6,B4GALT3,PPP1R12B,CHD1,NUP37,PKP1,CLOCK,DNM3,MATR3,F11R,MTX3,C12orf42,C14orf119,DNMT3A,RAN,EFNA5,SBNO1,FNIP1,KCNN2" MicroRNA hsa-miR-30c-2*:mirSVR_highEffct hsa-miR-30c-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.25E-11 1.73E-07 1.15E-10 1.05E-09 42 1120 "WDR35,ATP7B,ARHGEF7,PNP,MPZL1,LDB2,PCK2,CDK18,WDFY2,HOMER1,AKAP6,COPA,PM20D1,TTC37,DCAF8,SPATA18,PSME1,CEP120,PTPRH,GNPDA2,NR1I3,FAM129A,AASDH,MBNL2,KIRREL1,DLEU1,RELL1,STAB2,RUBCNL,SLC8A1,PKD2L2,WDCP,MYT1L,PDS5B,ERAP1,NEDD1,KLHL20,TMED2,CRB1,TECRL,DCP2,LMNB1" MicroRNA hsa-miR-661:mirSVR_highEffct hsa-miR-661:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.29E-11 1.75E-07 1.16E-10 1.06E-09 27 492 "FBRSL1,APC,NCOA1,MYH6,LDB2,PCK2,VIT,POLN,DNM3,ZNF586,BIVM,NUDT12,PTPRC,NR1I3,RNF31,RB1,GP6,GMPR2,TNFRSF19,PIBF1,FTLP10,CIDEB,JPH4,KMT5A,TNR,IL6ST,LINC01913" MicroRNA hsa-miR-373-3p:Functional MTI Functional MTI miRTarbase 3.60E-11 1.91E-07 1.27E-10 1.16E-09 28 531 "MAP1B,ULK1,BCL2L2,CFL2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,PACRGL,LATS2,SBNO1,KLHL12,IRF9,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,BAZ1A,TXK,LMNB1" MicroRNA hsa-miR-6867-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.81E-11 2.03E-07 1.34E-10 1.23E-09 26 459 "RGS5,FBRSL1,STXBP6,FGFRL1,PNP,CAMK4,FAM177A1,CFL2,NRXN1,FAM163A,BRI3BP,LRRTM2,EIF2AK2,DCAF8,SLC35F6,RGS4,LATS2,FOXG1,PLEKHA6,NMNAT2,TNR,IGF1,ZFHX2,IL6ST,LAD1,ZDHHC20" MicroRNA hsa-miR-19a-3p:Functional MTI Functional MTI miRTarbase 3.93E-11 2.09E-07 1.38E-10 1.26E-09 29 571 "MCC,CFL2,HOMER1,GNPTAB,CLOCK,SNX17,CEP350,KLHL3,G3BP2,MTX3,WDR1,RAN,RASA1,RNF4,MBNL2,CLIP1,PAICS,GAK,RAPGEF6,KLHL20,ZNF544,GRSF1,RAB2B,ZNF721,TENT2,DCP2,SPTSSA,LMLN,KIT" MicroRNA hsa-miR-425*:mirSVR_lowEffct hsa-miR-425*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.13E-11 2.20E-07 1.45E-10 1.33E-09 27 497 "TMEM132B,COG6,APC,NOP14,CENPBD1P1,BTF3,CHD1,BRI3BP,NOS1AP,DCAF8,MATR3,KLHL3,C14orf119,GALNT14,LRPPRC,ADGRV1,FCAR,DCAF11,IKBIP,MAST4,STON1,TMEM174,HPCAL1,NSD2,FIP1L1,KIR2DS4,TTC7A" MicroRNA hsa-miR-3132:mirSVR_highEffct hsa-miR-3132:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-11 2.21E-07 1.46E-10 1.33E-09 32 691 "RALGAPA1,APC,CDKL4,CD1E,UHMK1,TTC37,GLT8D2,SNX17,NR1H4,RNF31,DTD2,MEMO1,EIF2B1,GMPR2,ARHGEF40,N4BP2,CYP1B1-AS1,CIDEB,EAPP,HSPH1,MCCC2,NEDD1,MAST4,TBC1D1,MTUS2,ARHGEF28,EML4,TEP1,TMPO,TNR,IL6ST,AXDND1" MicroRNA hsa-miR-326:mirSVR_highEffct hsa-miR-326:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.46E-11 2.37E-07 1.56E-10 1.43E-09 32 693 "RALGAPA1,TAF1B,FCRLB,PDGFRA,RCBTB2,ITGBL1,LINC01085,ATAD2B,THAP6,AKAP6,DNM3,SNX17,LINC01257,TOMM40L,FGF9,TNFRSF19,VEZT,SLC22A4,CYP1B1-AS1,ZNF274,CD244,NPAS3,MCCC2,ERBIN,ZNF544,ADAM17,CRB1,ZBTB49,ZNF876P,ZNF470,ZBED3-AS1,SLAMF9" MicroRNA hsa-miR-132-3p:TargetScan hsa-miR-132-3p TargetScan 4.52E-11 2.41E-07 1.58E-10 1.45E-09 23 359 "KIAA1211,NOVA1,PDGFRA,CFL2,CHD1,HECTD1,CLOCK,PRKD1,DCAF8,DNMT3A,RASA1,RB1,PCGF3,FOXO1,CCDC88A,KIF21B,KDM5B,NMNAT2,GRSF1,MSH6,IRF1,LMLN,KIF2A" MicroRNA hsa-miR-212-3p:TargetScan hsa-miR-212-3p TargetScan 4.52E-11 2.41E-07 1.58E-10 1.45E-09 23 359 "KIAA1211,NOVA1,PDGFRA,CFL2,CHD1,HECTD1,CLOCK,PRKD1,DCAF8,DNMT3A,RASA1,RB1,PCGF3,FOXO1,CCDC88A,KIF21B,KDM5B,NMNAT2,GRSF1,MSH6,IRF1,LMLN,KIF2A" MicroRNA hsa-miR-545:PITA hsa-miR-545:PITA_TOP PITA 4.53E-11 2.41E-07 1.58E-10 1.45E-09 31 653 "MAP1B,NYNRIN,HOMEZ,APBB2,NCOA1,ATP2B4,BCL2L2,CACNA1E,DCLK1,PDE4D,CFL2,ATAD2B,HECTD1,CSNK1G3,DNM3,G3BP2,RASA1,ARGLU1,FAM172A,ZNF219,SLC22A5,MYT1L,KIF21B,KDM3B,SRP54,ADGRL3,TFDP1,RAB2B,FZD10,GPN1,HTR2A" MicroRNA hsa-miR-183:PITA hsa-miR-183:PITA_TOP PITA 4.58E-11 2.44E-07 1.60E-10 1.47E-09 20 265 "FCHO2,PDE4D,HOMER1,CSNK1G3,DMXL1,KLHL3,SACS,NTN4,LATS2,CLIP1,SUCO,FOXO1,BRMS1L,ERBIN,GJA3,EML4,RIMBP2,SLAIN1,ZMYM2,KIF2A" MicroRNA hsa-miR-1274b:mirSVR_highEffct hsa-miR-1274b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.61E-11 2.45E-07 1.61E-10 1.47E-09 26 463 "KIAA1211,COG6,B4GALT3,THAP6,TSEN15,RNASEL,MBNL2,STK32B,SUPT20H,ALKAL2,TADA1,ZNF667,NPAS3,KDM3B,STRN,STON1,AP4S1,RASSF6,NPL,RXFP2,YTHDC2,SPTSSA,LINC00272,KCNJ9,FIP1L1,PABPN1" MicroRNA hsa-miR-2116-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.65E-11 2.47E-07 1.62E-10 1.49E-09 16 157 "NLN,NRL,CAMK4,XPR1,PIGR,THAP6,DNMT3A,DLEU1,RAPGEF6,UHRF1BP1L,MRPS27,ACSL6,TEP1,AP4S1,TENT2,LMLN" MicroRNA hsa-miR-197:mirSVR_highEffct hsa-miR-197:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.70E-11 2.50E-07 1.64E-10 1.50E-09 31 654 "STXBP6,SLC4A4,CAST,PDGFRA,CHIT1,PGGT1B,WDFY2,LYSMD3,SNCAIP,CEP135,FAM169A,PARPBP,RAN,RNF31,ZNF329,NTN4,UGT2A3,FAM172A,ETF1,N4BP2L2,SUPT20H,BRMS1L,CCDC88A,UHRF1BP1L,ATP8A2,COMMD6,ARHGEF28,FCRL6,LINC00272,KCNN2,RILPL2" MicroRNA hsa-miR-1271:mirSVR_highEffct hsa-miR-1271:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.73E-11 2.51E-07 1.65E-10 1.51E-09 35 820 "ATP2B4,ARHGEF7,CCNA1,NOVA1,CACNA1E,CAST,LDB2,CDK17,VIT,PGGT1B,THAP6,HOMER1,LYSMD3,GLT8D2,TBC1D4,NTN4,TXNDC15,SAP18,FOXO1,SUPT20H,NUBPL,SLC22A5,MYO16,OXGR1,MCCC2,PSME4,METAP2,GPR12,ARHGEF28,RNF17,SLAIN1,YTHDC2,ZNF10,LCP1,RMST" MicroRNA hsa-miR-492:mirSVR_lowEffct hsa-miR-492:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.82E-11 2.56E-07 1.68E-10 1.54E-09 41 1088 "MCC,ADD1,SNX24,PPFIA4,AACS,NCOA1,SLC4A4,NFATC4,ARHGEF7,RAB29,NOVA1,GLT1D1,ATAD2B,PTPRVP,RNASE9,SNCAIP,VCAN,MPHOSPH8,ZNF586,SPATA18,RABGAP1L,NR1H4,DNMT3A,LAP3,LATS2,GRTP1,SDC1,FOXG1,NUBPL,ZNF605,ZNF274,KHNYN,NCSTN,CRB1,TPO,ARHGAP30,DCP2,ZFHX2,ZNF84,ZBED3-AS1,SPATA13" MicroRNA hsa-miR-3187:mirSVR_highEffct hsa-miR-3187:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.83E-11 2.57E-07 1.68E-10 1.54E-09 30 615 "RALGAPA1,CCNB1,RGSL1,CFL2,PIGR,ANAPC4,CRHBP,VCAN,NUDT12,TINF2,RB1,TXNDC15,MPHOSPH9,MARVELD2,POLK,SH3BP2,BRMS1L,PDS5B,RAPGEF6,ERBIN,PPARGC1A,LINC02393,ANO4,NT5C1B,LINC01551,RASSF6,ADAMTS19,TADA2B,ZMYM2,LINC01913" MicroRNA hsa-miR-27a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.97E-11 2.64E-07 1.73E-10 1.58E-09 25 429 "ABL2,MAP1B,ADD1,NLN,SEMA6A,APBB2,APC,KCTD12,ATP7B,LYSMD3,ITSN2,DNAJC27,TOMM40L,SUCO,FOXO1,WDCP,MRPS14,PDS5B,MRPS27,ZBTB37,LPIN1,HMGCR,IGF1,CAB39L,SPATA13" MicroRNA hsa-miR-3941:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.97E-11 2.64E-07 1.73E-10 1.58E-09 25 429 "SMIM15,SYT2,FAM177A1,CFL2,ITGBL1,NUP37,BRI3BP,CEP135,DMXL1,KLHL3,ATG10,FGF9,BRMS1L,SLC12A2,SLC22A4,LILRB1,PPARGC1A,RASSF6,TECRL,NLRP8,DCP2,IL6ST,CCDC169,ZMYM2,SPATA13" MicroRNA hsa-miR-586:PITA hsa-miR-586:PITA_TOP PITA 5.08E-11 2.70E-07 1.76E-10 1.62E-09 28 539 "BIRC6,NCOA1,KCTD12,CAMK4,CDK17,PDE4D,SNX6,THAP6,HOMER1,STRN3,PREPL,CSNK1G3,PRKD1,ZFYVE16,SREK1,TMEM33,MBNL2,SAP18,CCDC88A,ERBIN,PCDH17,MTUS2,ADGRL3,TCF7,SLAIN1,NSD2,DCP2,IGF1" MicroRNA hsa-miR-1256:mirSVR_highEffct hsa-miR-1256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.23E-11 2.78E-07 1.82E-10 1.66E-09 30 617 "ANKRD34B,DAOA,PCDH9,CFL2,WDFY2,CPNE6,CFAP54,PTPRVP,HOMER1,AKAP6,TAPT1,SNCAIP,VCAN,COG3,C12orf42,POLR1D,DEPDC4,FOXG1,CCDC88A,ZNF605,PDS5B,ERAP1,LRCH1,MIMT1,ANO4,ADAMTS19,ZMYM2,DNAH10,RMST,LIG4" MicroRNA hsa-miR-27a*:mirSVR_highEffct hsa-miR-27a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.48E-11 2.91E-07 1.90E-10 1.74E-09 25 431 "SNX24,BTF3,CD1D,SNX6,DNM3,FCRL2,DMXL1,PARPBP,RNF219,EIF2D,UGT2A3,TBC1D19,DLEU1,PCGF3,ELOVL7,FOXG1,CYP1B1-AS1,SNRPF,KIF21B,ADGRA3,GZMB,LHX9,FAM151B,RMST,IFT88" MicroRNA hsa-miR-495:PITA hsa-miR-495:PITA_TOP PITA 5.49E-11 2.92E-07 1.91E-10 1.74E-09 33 740 "ARHGAP5,STXBP6,NCOA1,CAST,FCHO2,PCDH9,PDE4D,CHD1,SNX6,HOMER1,CLOCK,DNMT3A,RAN,NTN4,MBNL2,FAM172A,ETF1,GORAB,SUCO,FOXG1,FBXO11,ALKAL2,SLC8A1,MYT1L,PCDH17,STRN,ADGRA3,TCF7,EML4,KLF12,YTHDC2,IGF1,FIP1L1" MicroRNA hsa-miR-885-3p:mirSVR_lowEffct hsa-miR-885-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.50E-11 2.92E-07 1.91E-10 1.75E-09 34 782 "ADORA1,NYNRIN,DHX37,NOP14,ATP2B4,ARHGEF7,CHAMP1,CCNB1,PCDH9,GLT1D1,SNX6,PTPRVP,THTPA,PIGG,COCH,C12orf42,PXMP2,TSEN15,RASA1,SNORA53,MARVELD2,DRAM1,TMEM156,PIBF1,LIMCH1,GABRB1,TMEM183A,ZNF544,ADGRA3,KMT5A,NCSTN,AMTN,TTC41P,LTA4H" MicroRNA hsa-miR-3170:mirSVR_highEffct hsa-miR-3170:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.52E-11 2.94E-07 1.91E-10 1.75E-09 36 868 "NYNRIN,CD84,PNP,CFL2,MRPL57,CPNE6,SMIM14,ATAD2B,POU2F1,BRI3BP,ITSN2,CEP350,AASDH,CLIP4,SETDB2,RNASEL,MBNL2,FAM172A,ETF1,USP44,NDUFAF7,GORAB,TNFRSF19,G2E3,IVNS1ABP,SLC8A1,CCDC88A,UGGT2,TMEM183A,PCDH17,TECRL,TMEM174,NSD2,LHX9,RMST,AXDND1" MicroRNA hsa-miR-770-5p:mirSVR_highEffct hsa-miR-770-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.55E-11 2.95E-07 1.92E-10 1.76E-09 26 467 "CDKL4,CDK18,PDGFRA,LINC01085,STRN3,RCHY1,SACS,C12orf42,PACRGL,LATS2,MPHOSPH9,BORA,ADGRV1,FMO1,COMMD6,LPIN1,RNF17,GTF3C2,BAZ1A,C12orf73,IL6ST,ZMYM2,LINC00272,TMEM178A,DIAPH3,LMNB1" MicroRNA hsa-miR-495-3p:TargetScan hsa-miR-495-3p TargetScan 5.65E-11 3.01E-07 1.96E-10 1.79E-09 30 619 "APC,NCOA1,FGFRL1,CAST,GPR180,NUP37,POU2F1,CLOCK,F11R,DNMT3A,RAN,RASA1,MBNL2,ELOVL7,FOXG1,FBXO11,CCDC92,BRMS1L,CCDC88A,KDM5B,RAPGEF6,ATP8A2,NPAS3,METAP2,CNTN2,ACSL6,GRSF1,HMGCR,IGF1,LHX9" MicroRNA hsa-miR-765:mirSVR_highEffct hsa-miR-765:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.87E-11 3.12E-07 2.03E-10 1.86E-09 40 1049 "MDM4,NDRG2,SLAMF6,CENPBD1P1,STARD13,SLC5A6,CBLN3,TAF1B,LDB2,SCFD2,CDK18,RGSL1,THAP6,HOMER1,LYSMD3,DNM3,DCT,PARPBP,NR1H4,FAM228A,GUSBP3,EIF2D,PACRGL,DHRS2,TRAPPC13,TNFRSF19,IVNS1ABP,ARHGEF40,CCDC88A,ACIN1,LIMCH1,GAK,OXGR1,ZBTB37,PSME4,PAPPA2,IL6ST,CCDC169,GALP,FIP1L1" MicroRNA "TGTTTAC,MIR-30A-5P:MSigDB" "TGTTTAC,MIR-30A-5P:MSigDB" MSigDB 6.01E-11 3.20E-07 2.07E-10 1.90E-09 28 543 "SEMA6A,FCHO2,XPR1,PDE4D,CFL2,NCOR2,MATR3,DNMT3A,RASA1,MBNL2,USP44,FOXG1,RUBCNL,NR5A2,YPEL5,JPH4,KLHL20,PCDH17,TMED2,ADGRL3,ANO4,EML4,KHNYN,TDG,RIMBP2,TENT2,ZBTB41,FAM49A" MicroRNA "TGTTTAC,MIR-30B:MSigDB" "TGTTTAC,MIR-30B:MSigDB" MSigDB 6.01E-11 3.20E-07 2.07E-10 1.90E-09 28 543 "SEMA6A,FCHO2,XPR1,PDE4D,CFL2,NCOR2,MATR3,DNMT3A,RASA1,MBNL2,USP44,FOXG1,RUBCNL,NR5A2,YPEL5,JPH4,KLHL20,PCDH17,TMED2,ADGRL3,ANO4,EML4,KHNYN,TDG,RIMBP2,TENT2,ZBTB41,FAM49A" MicroRNA "TGTTTAC,MIR-30C:MSigDB" "TGTTTAC,MIR-30C:MSigDB" MSigDB 6.01E-11 3.20E-07 2.07E-10 1.90E-09 28 543 "SEMA6A,FCHO2,XPR1,PDE4D,CFL2,NCOR2,MATR3,DNMT3A,RASA1,MBNL2,USP44,FOXG1,RUBCNL,NR5A2,YPEL5,JPH4,KLHL20,PCDH17,TMED2,ADGRL3,ANO4,EML4,KHNYN,TDG,RIMBP2,TENT2,ZBTB41,FAM49A" MicroRNA "TGTTTAC,MIR-30D:MSigDB" "TGTTTAC,MIR-30D:MSigDB" MSigDB 6.01E-11 3.20E-07 2.07E-10 1.90E-09 28 543 "SEMA6A,FCHO2,XPR1,PDE4D,CFL2,NCOR2,MATR3,DNMT3A,RASA1,MBNL2,USP44,FOXG1,RUBCNL,NR5A2,YPEL5,JPH4,KLHL20,PCDH17,TMED2,ADGRL3,ANO4,EML4,KHNYN,TDG,RIMBP2,TENT2,ZBTB41,FAM49A" MicroRNA "TGTTTAC,MIR-30E-5P:MSigDB" "TGTTTAC,MIR-30E-5P:MSigDB" MSigDB 6.01E-11 3.20E-07 2.07E-10 1.90E-09 28 543 "SEMA6A,FCHO2,XPR1,PDE4D,CFL2,NCOR2,MATR3,DNMT3A,RASA1,MBNL2,USP44,FOXG1,RUBCNL,NR5A2,YPEL5,JPH4,KLHL20,PCDH17,TMED2,ADGRL3,ANO4,EML4,KHNYN,TDG,RIMBP2,TENT2,ZBTB41,FAM49A" MicroRNA hsa-miR-1289:mirSVR_highEffct hsa-miR-1289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.38E-11 3.39E-07 2.20E-10 2.01E-09 26 470 "STXBP6,CAD,CDKL2,PDGFRA,STRN3,FAM163A,VCAN,DNM3,PSME1,C14orf119,EFNA5,TXNDC15,RNF4,MARVELD2,POLK,DCAF11,KDM5B,NMNAT2,IQGAP2,DOCK9,GTF3C2,GPN1,PLB1,CHPT1,DNAH10,NUAK2" MicroRNA hsa-miR-506:PITA hsa-miR-506:PITA_TOP PITA 7.14E-11 3.80E-07 2.46E-10 2.25E-09 32 706 "MAP1B,NYNRIN,SEMA6A,FCHO2,PCDH9,FAM177A1,PDE4D,ATAD2B,AKAP6,CLOCK,ITSN2,PRKD1,SREK1,G3BP2,ELK3,ZNF219,CLIP1,SUCO,ALKAL2,SLC12A2,SLC22A5,IQGAP2,ANKLE2,PCDH17,PPIP5K2,METAP2,XPO4,TDG,GRSF1,IRF1,ZBTB41,KIF2A" MicroRNA hsa-miR-451:mirSVR_lowEffct hsa-miR-451:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.40E-11 3.93E-07 2.54E-10 2.33E-09 23 368 "NYNRIN,SEMA6A,ATP4B,CD1D,SCARB1,PREPL,MATR3,DHFR,CLIP1,N4BP2L2,RUBCNL,MBIP,NR5A2,CD244,NPAS3,SRP54,LPIN1,PPIP5K2,TCF7,GRSF1,ZNF140,ANKS1B,KIF2A" MicroRNA hsa-miR-124:PITA hsa-miR-124:PITA_TOP PITA 7.66E-11 4.08E-07 2.63E-10 2.41E-09 32 708 "MAP1B,NYNRIN,SEMA6A,FCHO2,PCDH9,FAM177A1,PDE4D,ATAD2B,AKAP6,CLOCK,ITSN2,PRKD1,SREK1,G3BP2,ELK3,ZNF219,CLIP1,SUCO,ALKAL2,SLC12A2,SLC22A5,IQGAP2,ANKLE2,PCDH17,PPIP5K2,METAP2,XPO4,TDG,GRSF1,IRF1,ZBTB41,KIF2A" MicroRNA hsa-miR-2276:mirSVR_highEffct hsa-miR-2276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.94E-11 4.22E-07 2.73E-10 2.50E-09 34 793 "RALGAPA1,SMIM15,BLZF1,FAM193A,ZNF542P,PCK2,RGSL1,AKAP6,LYSMD3,PRKD1,MATR3,FBXL5,NUDT12,DNMT3A,TMEM161B,LAP3,RGS12,PACRGL,FOXO1,VEZT,MBIP,UFM1,SLC8A1,ZNF605,GABRA2,MYT1L,JPH4,PCDH17,MAST4,TBC1D1,DOCK9,ZMYM2,TMEM178A,CAB39L" MicroRNA "AAGCACA,MIR-218:MSigDB" "AAGCACA,MIR-218:MSigDB" MSigDB 8.23E-11 4.38E-07 2.83E-10 2.59E-09 23 370 "BIRC6,SEMA6A,ARHGAP5,FCHO2,PDGFRA,NRXN1,THTPA,SACS,WDR1,RNF219,ARGLU1,MBNL2,CCDC88A,SLC12A2,KIF21B,SRP72,PPARGC1A,ANO4,RIMBP2,KLF12,ZBTB41,KIT,LMNB1" MicroRNA hsa-miR-424*:mirSVR_lowEffct hsa-miR-424*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.53E-11 4.53E-07 2.93E-10 2.68E-09 38 971 "TMEM132B,RGS5,SLC5A6,SCARB1,NFXL1,ZNF664,PDE4D,CHD1,PFKFB2,AKAP6,LYSMD3,KIAA0040,PIGG,C14orf119,RASA1,RGS12,SPATA9,SNORA53,CLIP1,FLT1,SUPT20H,NBEA,PAICS,SLC8A1,ZNF605,GABRB1,GJB6,KLHL20,ARHGEF28,TDG,TFDP1,LINC01551,BAZ1A,RIMBP2,ATP6V0A2,TENT2,PGAM5,DNAH10" MicroRNA hsa-miR-433:PITA hsa-miR-433:PITA_TOP PITA 8.75E-11 4.66E-07 3.00E-10 2.75E-09 19 245 "MAP1B,DDX55,UHMK1,CDK17,BOD1L1,GNPTAB,LRRTM2,CEP135,DNM3,SREK1,SACS,TMEM33,TBC1D19,CLIP1,NR5A2,SRP54,PPARGC1A,EML4,KLF12" MicroRNA hsa-miR-1255b:mirSVR_highEffct hsa-miR-1255b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.18E-11 4.88E-07 3.15E-10 2.88E-09 31 672 "FCGR2C,CD1E,CDK18,PDE6B,CFL2,VIT,NUP37,LACC1,BIVM,COG3,DMXL1,LOC439933,SUPT7L,FAM129A,SMC6,FAM228A,RGS4,RNASEL,RELL1,TM9SF1,MBIP,PAICS,NR5A2,ACIN1,NMNAT2,GJB6,MCCC2,LPIN1,AP4S1,TECRL,RMST" MicroRNA hsa-miR-3117:mirSVR_highEffct hsa-miR-3117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.32E-11 4.95E-07 3.19E-10 2.92E-09 30 632 "ADD1,KCTD12,FCRL3,FCRLB,ZNF664,PDGFRA,PIWIL1,ATAD2B,VCAN,CEP135,PIGG,DNMT3A,CLIP4,LGR6,DLEU1,ABCA11P,GORAB,VEZT,IVNS1ABP,TADA1,WDCP,SLC22A5,RBKS,MCCC2,UGT2A1,RNF17,NT5C1B,TMPO,MAEL,KIR3DL2" MicroRNA hsa-miR-4312:mirSVR_highEffct hsa-miR-4312:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.54E-11 5.07E-07 3.26E-10 2.99E-09 27 516 "COG6,CCNA1,CAMK4,CFAP54,THAP6,HOMER1,FAM53A,POU2F1,FCRL5,PSMA6,PACRGL,TXNDC15,ABCA11P,FCAR,FGF9,FLT3,SCYL2,CENPJ,ERBIN,ANO4,RNF17,TMPO,ANKS1B,ZMYM2,FAM151B,KIT,RPGRIP1" MicroRNA hsa-miR-32:PITA hsa-miR-32:PITA_TOP PITA 1.01E-10 5.35E-07 3.44E-10 3.15E-09 26 480 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-1201:mirSVR_highEffct hsa-miR-1201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-10 5.49E-07 3.53E-10 3.23E-09 28 556 "NLN,CUL4A,SNX24,NCOA1,MPZL1,CAST,FCHO2,PDGFRA,ZNF595,SPATA18,NUDT12,TSEN15,FAM129A,PCBD2,UTP15,TNFRSF19,UFM1,CGREF1,HSPH1,MCCC2,METAP2,TCF7,EML4,LINC01551,RAB2B,MAEL,ZNF876P,CHPT1" MicroRNA hsa-miR-423-5p:mirSVR_highEffct hsa-miR-423-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-10 5.85E-07 3.76E-10 3.44E-09 31 677 "MDM4,B4GALT3,NFATC4,SLC5A6,LINC02347,ODC1,PCSK1,CHIT1,CPNE6,PTPRVP,SPATA18,TINF2,G3BP2,TXNDC15,MARVELD2,FAM81B,FGFR3,SUCO,TADA1,CGREF1,SLC22A4,DCAF11,TMEM183A,ERAP1,AURKC,STON1,AP4S1,ZNF324B,PLB1,IRF1,LCP1" MicroRNA hsa-miR-1272:PITA hsa-miR-1272:PITA_TOP PITA 1.14E-10 6.05E-07 3.88E-10 3.56E-09 18 220 "RALGAPA1,APAF1,NOVA1,AKAP6,STRN3,TNFRSF19,CCDC88A,NR5A2,ATP11A,TCF7,EML4,KMT5A,KHNYN,COP1,RIMBP2,ZBTB41,LETM1,LOX" MicroRNA hsa-miR-876-3p:mirSVR_lowEffct hsa-miR-876-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-10 6.11E-07 3.92E-10 3.59E-09 43 1215 "BIRC6,TBC1D14,HOMEZ,SNX24,ATP1A2,FCHO2,LDB2,CHD1,ZNF595,SNX6,TAPT1,ITSN2,BIVM,PTPRC,NR1H4,GALNT14,DTD2,NTN4,MARVELD2,ARSK,SAP18,ELOVL7,MROH9,FLT1,FTLP10,SLC34A2,CCDC92,SLC8A1,C1orf112,GABRB1,RAPGEF6,PPARGC1A,INSM2,KMT5A,CRB1,RIMBP2,SLAIN1,YTHDC2,FIP1L1,RILPL2,LINC01913,NUAK2,SPRYD7" MicroRNA hsa-miR-152:PITA hsa-miR-152:PITA_TOP PITA 1.15E-10 6.12E-07 3.92E-10 3.59E-09 26 483 "MAP1B,PITPNM2,NCOA1,STARD13,PDE4D,CFL2,CHD1,HOMER1,LYSMD3,CLOCK,ITSN2,DMXL1,RNF219,FBXO11,SLC8A1,PPARGC1A,ATP11A,XPO4,ADAMTS19,HSP90B1,TENT2,DCP2,YTHDC2,IGF1,KIT,SPRYD7" MicroRNA hsa-miR-148b:PITA hsa-miR-148b:PITA_TOP PITA 1.15E-10 6.12E-07 3.92E-10 3.59E-09 26 483 "MAP1B,PITPNM2,NCOA1,STARD13,PDE4D,CFL2,CHD1,HOMER1,LYSMD3,CLOCK,ITSN2,DMXL1,RNF219,FBXO11,SLC8A1,PPARGC1A,ATP11A,XPO4,ADAMTS19,HSP90B1,TENT2,DCP2,YTHDC2,IGF1,KIT,SPRYD7" MicroRNA hsa-miR-148a:PITA hsa-miR-148a:PITA_TOP PITA 1.15E-10 6.12E-07 3.92E-10 3.59E-09 26 483 "MAP1B,PITPNM2,NCOA1,STARD13,PDE4D,CFL2,CHD1,HOMER1,LYSMD3,CLOCK,ITSN2,DMXL1,RNF219,FBXO11,SLC8A1,PPARGC1A,ATP11A,XPO4,ADAMTS19,HSP90B1,TENT2,DCP2,YTHDC2,IGF1,KIT,SPRYD7" MicroRNA hsa-miR-658:mirSVR_lowEffct hsa-miR-658:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-10 6.65E-07 4.25E-10 3.89E-09 39 1030 "ADD1,ACOX3,NYNRIN,CCNA1,SCARB1,PAH,FCRLB,CDK17,PIGR,THTPA,POU2F1,C12orf65,UBXN2A,DCAF8,F11R,DHFR,RGS12,RNASEL,MBNL2,ELK3,LGR6,PCGF3,F7,PCBD2,TMEM129,RELL1,TACC3,FOXO1,STAB2,FBXO11,POTEM,NFASC,DRC1,KMT5A,ZBTB49,ZBED3-AS1,MFSD2B,LCP1,NUAK2" MicroRNA hsa-miR-526b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-10 6.69E-07 4.28E-10 3.92E-09 30 640 "MCC,ULK1,BCL2L2,FCHO2,CFL2,PFKFB2,GNPTAB,BRI3BP,C12orf65,UBXN2A,DCAF8,FBXL5,OCIAD1,RABGAP1L,SLC35F6,C14orf119,RAN,EGLN3,FAM129A,RB1,REST,CLIP4,N4BP2L2,SUCO,ZNF446,ZBTB37,GTF2H3,TXK,UBC,ZDHHC20" MicroRNA hsa-miR-328:mirSVR_lowEffct hsa-miR-328:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.27E-10 6.74E-07 4.31E-10 3.94E-09 45 1316 "LRRC43,NLN,HOMEZ,SNX24,ZNF784,ARHGEF7,SLC5A6,LINC02347,ODC1,CD1E,SNTG2,PDE6B,CHD1,CHIT1,PTPRVP,THTPA,POU2F1,SNCAIP,ZFYVE16,TINF2,C12orf42,RNF219,LGR6,FCAR,TOMM40L,PLEKHA6,IVNS1ABP,CCDC88A,TMEM132D,SLC22A4,CYP1B1-AS1,NFASC,LILRB1,ANO4,TEP1,GZMB,TMPO,UBE2K,ARHGAP30,GUF1,IL25,PLB1,ZBED3-AS1,KCNJ9,EP400P1" MicroRNA hsa-miR-346:mirSVR_highEffct hsa-miR-346:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-10 6.78E-07 4.33E-10 3.97E-09 24 413 "KIAA1211,ATP1A2,CADM3,RILPL1,ZNF664,SNCAIP,SREK1,COG3,NUDT12,PARPBP,RGS4,MEMO1,RNASEL,TRAPPC12,TOMM40L,ATP8A2,ERBIN,LPIN1,ANO4,C5orf56,AP4S1,NPHS2,CHPT1,SPRYD7" MicroRNA hsa-miR-1914:mirSVR_highEffct hsa-miR-1914:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-10 6.89E-07 4.39E-10 4.02E-09 25 449 "MDM4,ZNF542P,FCGR2C,FCRLB,THTPA,POU2F1,DCAF8,CEP350,LGR6,BORA,FCAR,NDUFAF7,C1orf112,MYO16,ERAP1,MRPS27,MCCC2,LINC02393,KMT5A,TDG,TEP1,ADAMTS19,KLF12,KCNN2,TTC41P" MicroRNA hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA_TOP PITA 1.30E-10 6.92E-07 4.41E-10 4.04E-09 22 345 "SEMA6A,ARHGAP5,NCOA1,FCHO2,PDGFRA,CENPC,PIK3C2B,PKP1,HOMER1,AKAP6,CLOCK,SNCAIP,DNM3,CEP350,RAN,RASA1,RB1,MBNL2,ETF1,FOXO1,IVNS1ABP,KDM5B" MicroRNA hsa-miR-363:PITA hsa-miR-363:PITA_TOP PITA 1.32E-10 7.00E-07 4.46E-10 4.08E-09 26 486 "MAP1B,PITPNM2,SLC4A4,STARD13,NOVA1,FCHO2,XPR1,GPR180,STRN3,DMXL1,G3BP2,LATS2,RNF4,PCGF3,USP44,FNIP1,FOXG1,BRMS1L,PLEKHA6,ALKAL2,MYT1L,PDS5B,IQGAP2,GOLGA3,DOCK9,FZD10" MicroRNA hsa-miR-193b-3p:Functional MTI Functional MTI miRTarbase 1.36E-10 7.23E-07 4.61E-10 4.22E-09 35 853 "CUL4A,DHX37,ODC1,CDK17,SMIM14,NUP37,COPA,POLE,DNMT3A,IPO4,TMEM33,TRIM28,ELK3,BORA,EFS,GMPR2,TACC3,C1orf112,PUS1,CENPJ,HSPH1,MCCC2,GJB2,TBC1D1,TMED2,KMT5A,MSH6,HMGCR,WDR36,NSD2,IRF1,KIT,LETM1,LMNB1,SKA3" MicroRNA hsa-miR-3199:mirSVR_highEffct hsa-miR-3199:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-10 7.31E-07 4.65E-10 4.26E-09 26 487 "SNX24,CD84,ARHGEF7,FCHO2,PCK2,PFKFB2,ZNF595,RNASE9,IL20,TINF2,EIF2B1,MARVELD2,TOMM40L,SLC8A1,WDCP,GAK,NAAA,TMEM183A,NPAS3,MCCC2,EML4,ZBTB49,MAEL,PAPPA2,WDR36,PABPN1" MicroRNA hsa-miR-424-5p:TargetScan hsa-miR-424-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-15b-5p:TargetScan hsa-miR-15b-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-195-5p:TargetScan hsa-miR-195-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-16-5p:TargetScan hsa-miR-16-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-15a-5p:TargetScan hsa-miR-15a-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-497-5p:TargetScan hsa-miR-497-5p TargetScan 1.38E-10 7.34E-07 4.66E-10 4.26E-09 40 1080 "ABL2,NYNRIN,APC,ARHGAP5,BCL2L2,BTF3,CACNA1E,GAS2L3,CAST,CDK17,NUP37,HECTD1,POU2F1,CLOCK,NCOR2,BRI3BP,DCAF8,COG3,LATS2,SBNO1,MBNL2,MPHOSPH9,FGF9,FOXO1,FLT3,G2E3,MYT1L,CIDEB,NMNAT2,NPAS3,NFASC,PCDH17,PPIP5K2,KHNYN,GPN1,HMGCR,PAPPA2,HTR2A,IGF1,CHPT1" MicroRNA hsa-miR-660:mirSVR_highEffct hsa-miR-660:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-10 7.58E-07 4.80E-10 4.40E-09 33 768 "COG6,AACS,STARD13,PCDH9,CDK7,PFKFB2,THAP6,PTPRC,G3BP2,RNF219,DTD2,POLR1D,FAM172A,STK32B,ETF1,ELOVL7,GORAB,SDC1,FBXO11,NBEA,SLC8A1,LIMCH1,MEGF10,JPH4,ERAP1,OXGR1,NPAS3,CMPK2,PPARGC1A,METAP2,NT5C1B,FCRL6,LOX" MicroRNA hsa-miR-588:mirSVR_highEffct hsa-miR-588:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-10 8.08E-07 5.12E-10 4.69E-09 31 686 "CENPBD1P1,PPP1R12B,PCDH9,RGSL1,PDGFRA,ZNF595,ATAD2B,PTPRVP,SREK1,DMXL1,CEP350,AASDH,MPHOSPH9,FAM172A,GORAB,VEZT,CCDC92,MBIP,SLC12A2,ACIN1,GABRB1,ZNF544,TEP1,RAB2B,MAEL,TNR,RXFP2,ZNF470,FAM151B,DIAPH3,RNASE11" MicroRNA hsa-miR-3202:mirSVR_highEffct hsa-miR-3202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-10 8.18E-07 5.18E-10 4.74E-09 40 1084 "SLAMF6,NYNRIN,ATP12A,ATP2B4,CD84,NOVA1,ZNF664,PDGFRA,CFAP54,PIK3C2B,C1orf116,NGDN,ARGLU1,FAM228A,DTD2,SLC9C2,RNF4,FNIP1,SELP,SCYL2,CCDC88A,WDCP,CIDEB,JPH4,NAAA,EAPP,CMPK2,LRCH1,ZBTB37,MAST4,ZNF544,UTP20,METAP2,RNF212,FCRLA,TNR,ARHGAP30,PLB1,FIP1L1,NUAK2" MicroRNA hsa-miR-1305:PITA hsa-miR-1305:PITA_TOP PITA 1.56E-10 8.29E-07 5.24E-10 4.80E-09 25 453 "ARL1,MYBPC1,ZNF664,PCDH9,XPR1,SLC25A3,ATAD2B,STRN3,CLOCK,CEP350,KLHL3,SACS,G3BP2,RASA1,ETF1,DNAJC27,CLIP1,CHFR,MEGF10,NMU,KLF12,HMGCR,IGF1,ZNF470,ZNF140" MicroRNA hsa-miR-128-3p:Functional MTI Functional MTI miRTarbase 1.59E-10 8.43E-07 5.33E-10 4.88E-09 27 528 "ADD1,NLN,ARHGAP5,RILPL1,PIK3C2B,LYSMD3,ITSN2,PTGS2,SUPT7L,ZNF329,ETF1,DNAJC27,TOMM40L,SUCO,NBEA,WDCP,MRPS14,MRPS27,KDM3B,ZBTB37,COX18,RASSF6,HAL,HSP90B1,DCP2,IGF1,LMNB1" MicroRNA hsa-miR-519e:mirSVR_highEffct hsa-miR-519e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-10 8.67E-07 5.48E-10 5.02E-09 30 647 "ATP1A2,LINC02347,NOVA1,PCCA,CDK18,RCBTB2,THAP6,AKAP6,MPC2,TAPT1,EPGN,CLOCK,LACC1,CLIP4,LATS2,BORA,DRAM1,SUCO,GOLGA2P5,NUBPL,UFM1,SCYL2,TMEM183A,IQGAP2,DOCK9,NT5C1B,NPL,FAM151B,SPRYD7,AXDND1" MicroRNA hsa-miR-877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-10 8.75E-07 5.52E-10 5.06E-09 29 607 "AACS,SLC5A6,SCARB1,PIGR,PIK3C2B,DCAF8,PIGG,WDR1,ARGLU1,IPO4,LRPPRC,TRIM28,ATP6AP1L,TMEM156,FGF9,LIMCH1,SNRPF,RAPGEF6,KDM3B,ERBIN,GOLGA3,SPIC,EML4,KHNYN,XPO4,MSH6,FIP1L1,LETM1,PABPN1" MicroRNA hsa-miR-323b-5p:mirSVR_highEffct hsa-miR-323b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-10 9.08E-07 5.73E-10 5.24E-09 25 455 "SLAMF6,HOMEZ,FCGR2C,LINC01085,ATAD2B,UGT2B28,TAPT1,ZFYVE16,PIGG,SREK1,PTPRC,RASA1,MBNL2,KLHL12,GORAB,FGFR3,PIBF1,CCDC88A,NPAS3,FCRLA,TPO,VRK2,DCP2,ZMYM2,RILPL2" MicroRNA hsa-miR-381-3p:TargetScan hsa-miR-381-3p TargetScan 1.71E-10 9.09E-07 5.73E-10 5.24E-09 29 608 "MCC,BIRC6,KIAA1211,APC,KCTD12,NFKBIA,CHD1,NRXN1,PIK3C2B,NUP37,HECTD1,HEATR5A,LYSMD3,CLOCK,NTN4,SBNO1,PCGF3,ELOVL7,NBEA,PLEKHA6,NR5A2,GABRB1,PDS5B,KDM5B,NFASC,ANO4,ATP6V0A2,KLF12,HMGCR" MicroRNA hsa-miR-9-5p:Functional MTI Functional MTI miRTarbase 1.71E-10 9.09E-07 5.73E-10 5.24E-09 22 350 "MAP1B,MCC,MDM4,CUL4A,APBB2,STARD13,UHMK1,BOD1L1,POU2F1,NCOR2,DMXL1,MTX3,ATG10,REST,SPON2,SDC1,FOXO1,NBEA,SLC22A5,NMNAT2,TGFBI,LOX" MicroRNA hsa-miR-563:mirSVR_highEffct hsa-miR-563:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-10 9.09E-07 5.73E-10 5.24E-09 22 350 "KIAA1211,SNX24,NOP14,ASCL1,ASTN1,PCK2,THAP6,CSNK1G3,EIF2AK2,RASA1,RGS4,PACRGL,MAEA,RELL1,POLK,GABRA2,KIF21B,JPH4,EAPP,NPAS3,HEXB,FIP1L1" MicroRNA hsa-miR-24-3p:TargetScan hsa-miR-24-3p TargetScan 1.74E-10 9.28E-07 5.84E-10 5.35E-09 28 569 "MATN3,MCC,NLN,NCOA1,BCL2L2,CACNA1E,SCARB1,NFXL1,FCRLB,PDGFRA,ATAD2B,MATR3,PIGG,KLHL3,RASA1,FGFR3,PLEKHA6,DCAF11,KIF21B,NFASC,PCDH17,ACSL6,EML4,KHNYN,ATP6V0A2,IRF1,KIF2A,LOX" MicroRNA hsa-miR-802:TargetScan hsa-miR-802 TargetScan 1.78E-10 9.47E-07 5.96E-10 5.45E-09 20 286 "BIRC6,NLN,APBB2,APC,BTF3,DCLK1,PDE4D,PIK3C2B,BOD1L1,POU2F1,MATR3,G3BP2,RAN,ARGLU1,MBNL2,DLEU1,PCGF3,NMNAT2,RAPGEF6,LCP1" MicroRNA hsa-miR-554:mirSVR_highEffct hsa-miR-554:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-10 9.60E-07 6.03E-10 5.52E-09 22 351 "CD84,EPS8L1,PSME2,G3BP2,DTD2,RGS12,IRF9,TOMM40L,N4BP2L2,TNFRSF19,ARHGEF40,TADA1,CCDC88A,KDM5B,PPARGC1A,GOLGA3,ACTR6,TMPO,IL6ST,SPTSSA,GALP,RNASE11" MicroRNA hsa-miR-3126-5p:mirSVR_highEffct hsa-miR-3126-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-10 9.65E-07 6.06E-10 5.55E-09 28 570 "SLAMF6,CD84,CCNA1,CBLN3,PCSK1,CDK18,RGSL1,ZNF595,ADGRF3,HOMER1,AKAP6,CEP350,POLR1D,FNIP1,SELP,ZCCHC8,ZNF667,YPEL5,EFR3B,DCAF11,ZNF544,ADGRA3,ARHGEF28,EML4,LINC01551,ATP6V0A2,LHX9,KIR3DL1" MicroRNA hsa-miR-1255a:mirSVR_highEffct hsa-miR-1255a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-10 9.99E-07 6.27E-10 5.74E-09 31 692 "FCGR2C,CD1E,CDK18,PDE6B,CFL2,VIT,NUP37,LACC1,BIVM,COG3,DMXL1,LOC439933,SUPT7L,FAM129A,SMC6,FAM228A,RGS4,RNASEL,RELL1,TM9SF1,MBIP,PAICS,NR5A2,ACIN1,NMNAT2,GJB6,LPIN1,METAP2,AP4S1,TECRL,RMST" MicroRNA "TGCACTT,MIR-519C:MSigDB" "TGCACTT,MIR-519C:MSigDB" MSigDB 1.88E-10 1.00E-06 6.27E-10 5.74E-09 24 421 "MAP1B,BIRC6,BCL2L2,FCHO2,PDGFRA,CFL2,FBXL5,SACS,WDR1,RNF31,RB1,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,ERBIN,KLHL20,KLF12,NSD2,IGF1,SELENOI,KCNN2" MicroRNA "TGCACTT,MIR-519A:MSigDB" "TGCACTT,MIR-519A:MSigDB" MSigDB 1.88E-10 1.00E-06 6.27E-10 5.74E-09 24 421 "MAP1B,BIRC6,BCL2L2,FCHO2,PDGFRA,CFL2,FBXL5,SACS,WDR1,RNF31,RB1,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,ERBIN,KLHL20,KLF12,NSD2,IGF1,SELENOI,KCNN2" MicroRNA "TGCACTT,MIR-519B:MSigDB" "TGCACTT,MIR-519B:MSigDB" MSigDB 1.88E-10 1.00E-06 6.27E-10 5.74E-09 24 421 "MAP1B,BIRC6,BCL2L2,FCHO2,PDGFRA,CFL2,FBXL5,SACS,WDR1,RNF31,RB1,ELK3,FGF9,FOXG1,NBEA,BRMS1L,CCDC88A,ERBIN,KLHL20,KLF12,NSD2,IGF1,SELENOI,KCNN2" MicroRNA hsa-miR-922:PITA hsa-miR-922:PITA_TOP PITA 1.89E-10 1.01E-06 6.31E-10 5.78E-09 23 386 "MAP1B,SEMA6A,RILPL1,PCCA,CKMT2,STRN3,LYSMD3,CSNK1G3,DNM3,BIVM,SACS,G3BP2,RASA1,LATS2,SCYL2,NR5A2,STRN,INSM2,TCF7,XPO4,ADAMTS19,KLF12,KIF3C" MicroRNA hsa-miR-377:PITA hsa-miR-377:PITA_TOP PITA 2.05E-10 1.09E-06 6.82E-10 6.24E-09 25 459 "MAP1B,CUL4A,NCOA1,KCTD12,SYT2,PDE4D,SMIM14,AKAP6,TAPT1,PRKD1,RASA1,RB1,LATS2,NBEA,IQGAP2,PCDH17,PPARGC1A,PSME4,TMED2,EML4,XPO4,GRSF1,NSD2,IGF1,KIF2A" MicroRNA hsa-miR-1975:mirSVR_lowEffct hsa-miR-1975:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.05E-10 1.09E-06 6.82E-10 6.24E-09 47 1436 "TMEM132B,ACOX3,ULK1,APAF1,ATP1A2,SLC4A4,CCNA1,LDB2,CCNB1,CHD1,WDFY2,MRPL57,PIK3C2B,ATAD2B,THAP6,C1orf116,STRN3,FAM163A,RCHY1,FAM169A,PRKD1,LOC439933,G3BP2,RABGAP1L,WDR1,AASDH,RGS4,EFNA5,CLIP1,PCBD2,SDC1,PEAR1,FLT1,RASA3,SLC12A2,C1orf112,CD244,OXGR1,LRCH1,ZNF544,TBC1D1,INSM2,DOCK9,STARD4,ZBTB41,PGAM5,FAM151B" MicroRNA hsa-miR-329:mirSVR_highEffct hsa-miR-329:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.09E-10 1.11E-06 6.94E-10 6.35E-09 31 695 "ATP6V1G3,FAM177A1,PDE4D,PDGFRA,TM9SF2,LYSMD3,CSNK1G3,PRKD1,TSEN15,NTN4,PCGF3,TOMM40L,FBXO11,NBEA,NUBPL,P2RX2,ZNF667,UGGT2,CENPJ,GJA3,TDG,NT5C1B,TGFBI,LINC01551,STARD4,IL6ST,LHX9,KIR2DL4,SPRYD7,PABPN1,ZNF304" MicroRNA hsa-miR-421:PITA hsa-miR-421:PITA_TOP PITA 2.24E-10 1.19E-06 7.43E-10 6.80E-09 22 355 "ARHGAP5,ARL1,SLC4A4,LDB2,PDGFRA,CFL2,SLC25A3,ATAD2B,STRN3,LYSMD3,PRKD1,RASA1,ELK3,FAM172A,DNAJC27,PCDH17,PPARGC1A,RAB2B,ADAMTS19,DCP2,IGF1,KIF3C" MicroRNA hsa-miR-1289:mirSVR_lowEffct hsa-miR-1289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-10 1.26E-06 7.85E-10 7.19E-09 43 1244 "SLAMF6,BLZF1,FAM193A,ATP1A2,ARHGEF7,RAB29,NOVA1,XPR1,WDFY2,CMTM5,UBXN2A,FCRL5,PSMA6,EPS8L1,CEP350,F11R,RB1,LGR6,STX2,DRAM1,CWC27,ELOVL7,VEZT,NLRP2,STPG4,SLC12A2,WDCP,SLC22A4,MEGF10,ATP8A2,KDM3B,NFASC,STON1,NT5C1B,AP4S1,TMPO,TPO,ARHGAP30,TXK,ZNF324B,LHX9,KIR2DL4,LINC01913" MicroRNA hsa-miR-191:mirSVR_lowEffct hsa-miR-191:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-10 1.27E-06 7.95E-10 7.28E-09 27 538 "SEMA6A,ATP2B4,STARD13,NOVA1,AMDHD1,CHAMP1,CHD1,SNX6,THAP6,FBXL5,CEP350,PTPRC,SACS,RABGAP1L,TMEM33,SETDB2,EFNA5,FCGR2B,GORAB,FOXO1,SLC12A2,ZNF274,RNF212,MAEL,CCDC190,CHPT1,PABPN1" MicroRNA hsa-miR-1231:mirSVR_highEffct hsa-miR-1231:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-10 1.28E-06 7.96E-10 7.29E-09 29 617 "ABL2,NYNRIN,STARD13,LINC02347,NOVA1,ZNF664,RGSL1,UBXN2A,FCRL2,B3GLCT,AASDH,RNASEL,GRTP1,FLT1,GABRB1,JPH4,ZNF274,UGT2A1,C5orf56,STON1,AP4S1,TMPO,HEXB,SLAIN1,VRK2,LINC00272,FIP1L1,LINC01913,MICU2" MicroRNA hsa-miR-513a-5p:PITA hsa-miR-513a-5p:PITA_TOP PITA 2.41E-10 1.28E-06 7.98E-10 7.31E-09 19 260 "ANKRD34B,CBLN3,UHMK1,CFL2,CHD1,ATAD2B,HOMER1,DNM3,BIVM,RAN,LATS2,ETF1,USP44,NPAS3,PPARGC1A,GTF3C2,KLF12,UBE2K,DCP2" MicroRNA hsa-miR-656:PITA hsa-miR-656:PITA_TOP PITA 2.52E-10 1.34E-06 8.35E-10 7.64E-09 30 659 "MATN3,MCC,NLN,PPP1R12B,FGFRL1,NOVA1,UHMK1,PCDH9,PCSK1,CDK18,NRXN1,SREK1,PTGS2,DMXL1,TMEM161B,CLIP4,MBNL2,PCGF3,FLT3,CCDC88A,CHFR,PDS5B,STRN,UTP20,TDG,TNR,ATP6V0A2,UBE2K,ZBTB41,CAB39L" MicroRNA hsa-miR-146b-3p:mirSVR_highEffct hsa-miR-146b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-10 1.37E-06 8.49E-10 7.78E-09 25 464 "BTF3,LINC02347,NFXL1,PCCA,THAP6,POLE,SNCAIP,DMXL1,DNMT3A,FAM129A,RGS4,DHRS2,GORAB,TNFRSF19,TMEM183A,STRN,ADGRL3,GPR12,TEP1,AP4S1,ZNF26,IL6ST,KCNJ9,TTC41P,FAM71C" MicroRNA hsa-miR-411:mirSVR_highEffct hsa-miR-411:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.60E-10 1.38E-06 8.60E-10 7.87E-09 27 540 "KCTD12,NEDD8,CCNA1,CAST,CENPC,ITGBL1,ATAD2B,PREPL,VCAN,PTGS2,FBXL5,C14orf119,GRTP1,ABCA11P,NDUFAF7,FOXO1,GABRA2,NAAA,GJB2,EML4,ZNF721,ADAMTS19,C12orf73,ZBED3-AS1,KIR2DL1,KIR2DL4,KIR3DL1" MicroRNA hsa-miR-425:mirSVR_highEffct hsa-miR-425:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.75E-10 1.46E-06 9.09E-10 8.32E-09 35 876 "ARL1,B4GALT3,BTF3,MPZL1,CFL2,VIT,SMIM14,CLOCK,NGDN,DDX59,SPATA18,RNF219,EGLN3,RGS4,TXNDC15,DNAJC27,SH3YL1,PCBD2,SUCO,VEZT,SLC22A5,LIMCH1,HSPH1,SRP72,LRCH1,LINC02393,TCF7,RASSF6,VRK2,IGF1,KCNT2,PLB1,RMST,IFT88,PABPN1" MicroRNA hsa-miR-15a*:mirSVR_highEffct hsa-miR-15a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.89E-10 1.54E-06 9.56E-10 8.75E-09 29 622 "SLAMF6,NOVA1,PDGFRA,COLEC11,SNX6,STRN3,SNCAIP,SREK1,PPP2R3C,RNF219,RGS4,NTN4,RNASEL,CWC27,GMPR2,POLK,ARHGEF40,MRPS27,SRP72,COMMD6,MAST4,ZNF544,KMT5A,DOCK9,COX18,RASSF6,HTR2A,RMST,LMNB1" MicroRNA hsa-miR-140-3p:mirSVR_highEffct hsa-miR-140-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.92E-10 1.55E-06 9.64E-10 8.83E-09 35 878 "SMIM15,NOVA1,FCRLB,PDE6B,CEP135,ZFYVE16,DHX9,AASDH,FAM228A,SPATA9,MARVELD2,CLIP1,FGF9,FOXG1,G2E3,ALKAL2,PKD2L2,NR5A2,PDS5B,CMPK2,SRP72,RBKS,METAP2,DOCK9,TDG,TPO,ADAMTS19,HPCAL1,SLAIN1,NLRP8,CCDC169,ZMYM2,TDRD3,ZBED3-AS1,LCP1" MicroRNA hsa-miR-940:mirSVR_highEffct hsa-miR-940:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-10 1.60E-06 9.93E-10 9.10E-09 33 791 "SLAMF6,PAH,CFL2,PFKFB2,ZNF595,CKMT2,PIGR,ADGRF3,POU2F1,PRKD1,SREK1,PTPRH,TINF2,GRTP1,DCUN1D2,LGR6,STX2,FAM172A,ETF1,DLEU1,CCDC92,JPH4,NAAA,COMMD6,LPIN1,UGT2A1,RIPK3,NCSTN,NPL,GUF1,WDR36,IL6ST,PABPN1" MicroRNA hsa-miR-3158:mirSVR_highEffct hsa-miR-3158:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-10 1.60E-06 9.94E-10 9.10E-09 30 664 "MDM4,COG6,HOMEZ,CUL4A,PPP1R12B,RGSL1,PDE4D,POU2F1,SMC6,UGT2A3,SAP18,PIBF1,MROH9,FBXO11,MBIP,IVNS1ABP,CIDEB,IQGAP2,NPAS3,NFASC,NPFFR2,ZBTB37,BRD8,ZNF544,MTUS2,TGFBI,HEXB,ARHGAP30,HTR2A,IFT88" MicroRNA hsa-miR-363*:mirSVR_highEffct hsa-miR-363*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.12E-10 1.66E-06 1.03E-09 9.40E-09 29 624 "RALGAPA1,MDM4,SEMA6A,LINC02347,CAST,ZNF595,ITGBL1,SNX17,PTPRC,NR1I3,TMEM161B,GP6,SAP18,SLC22A17,FNIP1,POLK,PAICS,SLC30A6,ERAP1,LRCH1,ANO4,RIPK3,KHNYN,CRB1,ADAMTS19,PLB1,NPHS2,RNASE11,LINC00442" MicroRNA hsa-miR-27a:PITA hsa-miR-27a:PITA_TOP PITA 3.12E-10 1.66E-06 1.03E-09 9.41E-09 30 665 "RALGAPA1,ABL2,MATN3,NLN,SEMA6A,PITPNM2,APAF1,NCOA1,B4GALT3,NEDD8,NOVA1,CDK18,PDGFRA,NRXN1,SMIM14,ITSN2,LRRTM2,CEP135,SREK1,MBNL2,FAM172A,PCGF3,SUCO,FOXO1,CCDC92,SLC8A1,NR5A2,PDS5B,DCP2,ZBTB41" MicroRNA hsa-miR-27b:PITA hsa-miR-27b:PITA_TOP PITA 3.12E-10 1.66E-06 1.03E-09 9.41E-09 30 665 "RALGAPA1,ABL2,MATN3,NLN,SEMA6A,PITPNM2,APAF1,NCOA1,B4GALT3,NEDD8,NOVA1,CDK18,PDGFRA,NRXN1,SMIM14,ITSN2,LRRTM2,CEP135,SREK1,MBNL2,FAM172A,PCGF3,SUCO,FOXO1,CCDC92,SLC8A1,NR5A2,PDS5B,DCP2,ZBTB41" MicroRNA hsa-miR-323a-3p:TargetScan hsa-miR-323a-3p TargetScan 3.23E-10 1.72E-06 1.06E-09 9.73E-09 22 362 "KIAA1211,ANKRD34B,CUL4A,FBRSL1,ARL1,KCTD12,PDE4D,KLHL3,G3BP2,DNMT3A,SBNO1,ELF1,FNIP1,SCYL2,MYT1L,PCDH17,ATP11A,METAP2,GRSF1,HMGCR,PAPPA2,IGF1" MicroRNA hsa-miR-193b*:mirSVR_highEffct hsa-miR-193b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.23E-10 1.72E-06 1.06E-09 9.73E-09 34 837 "LDB2,PCSK1,MRPL57,CPNE6,CLOCK,BRI3BP,ITSN2,UBXN2A,FCRL2,CEP350,DNMT3A,CLIP4,NTN4,SETDB2,RNASEL,FAM172A,CLIP1,TRAPPC13,NDUFAF7,TNFRSF19,FMO1,G2E3,CCDC88A,UGGT2,DCAF11,TMEM183A,PCDH17,FCRLA,NT5C1B,TENT2,NSD2,LHX9,FAM49A,AXDND1" MicroRNA hsa-miR-1912:mirSVR_highEffct hsa-miR-1912:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-10 1.77E-06 1.09E-09 1.00E-08 32 751 "BLZF1,NEDD8,CDKL2,CAST,PCSK1,LRRTM2,DNM3,COG3,NR1I3,B3GLCT,RB1,TXNDC15,ETF1,FCGR2B,PEAR1,MROH9,FOXO1,SLC12A2,MEGF10,UHRF1BP1L,NPAS3,COMMD6,PSME4,TMED2,METAP2,ADGRA3,GPR18,LINC01551,ADAMTS19,MZF1,SPTSSA,CAB39L" MicroRNA hsa-miR-3172:mirSVR_highEffct hsa-miR-3172:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-10 1.77E-06 1.09E-09 1.00E-08 34 838 "LDB2,PCSK1,MRPL57,CPNE6,CLOCK,BRI3BP,ITSN2,UBXN2A,FCRL2,CEP350,DNMT3A,CLIP4,NTN4,SETDB2,RNASEL,FAM172A,CLIP1,TRAPPC13,NDUFAF7,TNFRSF19,FMO1,G2E3,CCDC88A,UGGT2,DCAF11,TMEM183A,PCDH17,FCRLA,NT5C1B,TENT2,NSD2,LHX9,FAM49A,AXDND1" MicroRNA hsa-miR-517b:mirSVR_lowEffct hsa-miR-517b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-10 1.78E-06 1.10E-09 1.01E-08 29 626 "ADD1,APBB2,FGFRL1,BTF3,PDE4D,CHD1,HECTD1,STRN3,TAPT1,LYSMD3,VCAN,DMXL1,PTPRC,TSEN15,RB1,RGS12,GUSBP3,F7,FMO1,COMMD6,SULT1E1,PPIP5K2,CRB1,TRPC4,TXK,PLB1,KCNN2,RNASE11,LIG4" MicroRNA hsa-miR-378*:mirSVR_highEffct hsa-miR-378*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.38E-10 1.80E-06 1.11E-09 1.02E-08 28 586 "WDR35,AP1G2,RGSL1,ZNF595,CFAP54,TINF2,TSEN15,RNF219,MPHOSPH9,FAM172A,EFS,ABCA11P,TRAPPC13,SUPT20H,CCDC88A,FSHR,PDS5B,NPAS3,MRPS27,ANKLE2,MIMT1,TMED2,GPR12,ADAMTS19,ZNF550,HTR2A,FAM151B,KCNJ9" MicroRNA hsa-miR-423-3p:mirSVR_lowEffct hsa-miR-423-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.44E-10 1.83E-06 1.13E-09 1.03E-08 23 398 "IL17D,HOMEZ,ATP1A2,CADM3,PCCA,PIK3C2B,ITSN2,CLIP4,DLEU1,PCGF3,TMEM156,FCAR,TM9SF1,CCDC92,EFR3B,DOCK9,RNF17,LINC01551,TMPO,CENPH,PLB1,FIP1L1,ZNF304" MicroRNA hsa-miR-125a-5p:mirSVR_highEffct hsa-miR-125a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.50E-10 1.86E-06 1.15E-09 1.05E-08 25 471 "HOMEZ,BLZF1,STARD13,CD84,LINC02347,CHAMP1,POU2F1,RABGAP1L,NR1H4,GALNT14,FAM129A,RB1,TMEM161B,MEMO1,CGREF1,CD244,NEDD1,NPL,CCDC169,ZBED3-AS1,KCNN2,AXDND1,LIG4,LMNB1,IFT88" MicroRNA hsa-miR-633:PITA hsa-miR-633:PITA_TOP PITA 3.54E-10 1.88E-06 1.16E-09 1.06E-08 19 266 "NLN,KCTD12,NOVA1,ZNF664,CHD1,AKAP6,STRN3,DMXL1,CEP350,G3BP2,SMC6,LATS2,FBXO11,IVNS1ABP,MYT1L,PPARGC1A,ACSL6,STON1,CDK2AP1" MicroRNA hsa-miR-133a:mirSVR_highEffct hsa-miR-133a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.61E-10 1.92E-06 1.18E-09 1.08E-08 29 628 "PITPNM2,STXBP6,ATP7B,CAST,CCNB1,LTB4R,NGDN,CSNK1G3,CMTM5,PTPRH,PARPBP,NR1I3,PACRGL,FCAMR,MAEA,ETF1,DLEU1,G2E3,MCCC2,METAP2,TCF7,NPL,HEXB,UBE2K,TECRL,PLB1,KIF3C,AXDND1,SKA3" MicroRNA hsa-miR-133b:mirSVR_highEffct hsa-miR-133b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.61E-10 1.92E-06 1.18E-09 1.08E-08 29 628 "PITPNM2,STXBP6,ATP7B,CAST,CCNB1,LTB4R,NGDN,CSNK1G3,CMTM5,PTPRH,PARPBP,NR1I3,PACRGL,FCAMR,MAEA,ETF1,DLEU1,G2E3,MCCC2,METAP2,TCF7,NPL,HEXB,UBE2K,TECRL,PLB1,KIF3C,AXDND1,SKA3" MicroRNA hsa-miR-1909*:mirSVR_lowEffct hsa-miR-1909*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-10 1.92E-06 1.18E-09 1.08E-08 37 976 "ATP6V1G3,FAM193A,AACS,PNP,LDB2,RGSL1,SNX6,THAP6,TAPT1,EIF2AK2,G3BP2,TSEN15,DNMT3A,B3GLCT,MEMO1,PACRGL,RNF4,ELF1,F7,TOMM40L,NDUFAF7,FGFR3,FLT1,PAICS,SLC8A1,ATP8A2,COX7B2,KHNYN,NT5C1B,TFDP1,TGFBI,LINC01551,BAZ1A,TECRL,ZNF324B,KIT,AXDND1" MicroRNA hsa-miR-579:PITA hsa-miR-579:PITA_TOP PITA 3.63E-10 1.93E-06 1.19E-09 1.09E-08 24 435 "MAP1B,APAF1,APC,NOVA1,FCHO2,PDE4D,STRN3,DNM3,G3BP2,FOXO1,ZCCHC8,NBEA,SLC30A6,MEGF10,IQGAP2,NPAS3,ERBIN,PCDH17,PPARGC1A,DHRS4,FZD10,KLF12,DCP2,LHX9" MicroRNA hsa-miR-136*:mirSVR_lowEffct hsa-miR-136*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.76E-10 2.00E-06 1.23E-09 1.12E-08 33 798 "MAP1B,ARL1,ARHGEF7,LINC02347,DAOA,CAMK4,PCDH9,ZMYM5,CDK17,PDGFRA,CCDC122,RCHY1,LYSMD3,VCAN,FCRL5,LOC439933,FAM129A,B3GLCT,RB1,ETF1,ABCA11P,ADGRV1,CLIP1,FCGR2B,VEZT,GJA3,ADGRL3,C1QTNF9B,BAZ1A,TENT2,STARD4,KIT,LTA4H" MicroRNA hsa-miR-339-5p:mirSVR_highEffct hsa-miR-339-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.84E-10 2.04E-06 1.25E-09 1.15E-08 26 511 "STARD13,NOVA1,ZNF595,NRXN1,PIGR,NGDN,LRRTM2,EIF2AK2,ZNF586,DMXL1,RABGAP1L,ZNF329,KIRREL1,PCBD2,UTP15,SUPT20H,G2E3,BRMS1L,UFM1,ARHGEF40,KDM5B,TMEM183A,SULT1E1,NCSTN,NPL,DCP2" MicroRNA hsa-miR-323b-3p:mirSVR_highEffct hsa-miR-323b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.94E-10 2.10E-06 1.28E-09 1.18E-08 28 590 "SNX24,NOVA1,PGGT1B,WDFY2,VCAN,ZFYVE16,NR1H4,RB1,TMEM161B,SMC6,POLR1D,SNORA53,ELF1,DLEU1,ABCA11P,FCGR2B,FGFR3,SUCO,FLT3,FBXO11,NBEA,OXGR1,ERBIN,SCFD1,DOCK9,BAZ1A,MAEL,TMEM174" MicroRNA hsa-miR-4329:mirSVR_highEffct hsa-miR-4329:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.94E-10 2.10E-06 1.28E-09 1.18E-08 28 590 "COG6,B4GALT3,CHAMP1,CD1E,PCCA,RCBTB2,DHRS1,NUP37,ATAD2B,THAP6,GNPTAB,BRI3BP,CEP135,FCRL5,LOC439933,LRRN2,THADA,ZNF605,CGREF1,C1orf112,NAAA,LRCH1,PSME4,NCSTN,HAL,HEXB,ARHGAP30,SPRYD7" MicroRNA hsa-miR-421:TargetScan hsa-miR-421 TargetScan 3.95E-10 2.10E-06 1.29E-09 1.18E-08 21 332 "APBB2,ARHGAP5,PDGFRA,CFL2,PFKFB2,NUP37,ATAD2B,PRKD1,OCIAD1,RASA1,ARGLU1,PACRGL,SBNO1,ELK3,FAM172A,DNAJC27,ATP8A2,IL6ST,ANKS1B,LHX9,KIF3C" MicroRNA hsa-miR-1207-3p:mirSVR_highEffct hsa-miR-1207-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.00E-10 2.13E-06 1.30E-09 1.19E-08 30 672 "NCOA1,ARHGEF7,LINC02347,CDKL2,PDE4D,SMIM14,JAKMIP1,SNCAIP,DCAF8,COG3,CEP350,RABGAP1L,MBNL2,LGR6,TMEM156,FCAR,GORAB,N4BP2L2,FOXO1,NBEA,YPEL5,NMNAT2,MRPS27,KDM3B,MIMT1,NMU,ANO4,TCF7,MSH6,AXDND1" MicroRNA hsa-miR-187:mirSVR_lowEffct hsa-miR-187:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.14E-10 2.20E-06 1.35E-09 1.23E-08 31 715 "ACOX3,DDX55,AACS,FCRL3,ARHGEF7,MPZL1,ZNF664,CDK17,PDGFRA,HOMER1,UBXN2A,PRKD1,ZFYVE16,PIGG,NTN4,DHRS2,ADGRV1,TMEM156,TMEM129,FCAR,N4BP2L2,MEGF10,NAAA,RNF17,TMPO,TENT2,KIR2DL1,KIR2DL4,KIR2DS4,TTC41P,SLAMF9" MicroRNA hsa-miR-183-5p.1:TargetScan hsa-miR-183-5p.1 TargetScan 4.40E-10 2.34E-06 1.43E-09 1.31E-08 22 368 "MDM4,ATP2B4,CACNA1E,FCHO2,CCNB1,PDE4D,CSNK1G3,FAM169A,DMXL1,KLHL3,SACS,RABGAP1L,NTN4,FGF9,FOXO1,BRMS1L,HSPH1,NPAS3,EML4,RIMBP2,HTR2A,KIF2A" MicroRNA hsa-miR-432*:mirSVR_highEffct hsa-miR-432*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.41E-10 2.35E-06 1.43E-09 1.31E-08 28 593 "LINC02347,MPZL1,PDGFRA,THAP6,CRHBP,DCAF8,PTPRH,C14orf119,FAM129A,FAM228A,IPO4,MBNL2,PCGF3,TNFRSF19,SLC8A1,YPEL5,GABRB1,NEDD1,LRCH1,KLHL20,RIPK3,ZMYM2,FAM151B,NPHS2,KIT,LINC00442,AXDND1,LOX" MicroRNA hsa-miR-1263:mirSVR_highEffct hsa-miR-1263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.63E-10 2.46E-06 1.50E-09 1.38E-08 22 369 "NCOA1,RGSL1,CFAP54,TOGARAM2,FCRL2,ZFYVE16,NR1I3,B3GLCT,CLIP1,GORAB,TM9SF1,FBXO11,SCYL2,IVNS1ABP,ACIN1,CYP1B1-AS1,PPARGC1A,PPIP5K2,ANKS1B,ZBED3-AS1,CAB39L,IFT88" MicroRNA hsa-miR-769-5p:mirSVR_highEffct hsa-miR-769-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.73E-10 2.51E-06 1.53E-09 1.40E-08 27 555 "CD84,LINC02347,DAOA,LDB2,PCDH9,RCBTB2,CHIT1,ZNF595,THAP6,LRRTM2,FCRL5,FCRL2,BIVM,TBC1D4,DHRS2,ELOVL7,C1orf112,SLC22A4,RAPGEF6,LRCH1,UTP20,ZBTB49,GZMH,RIMBP2,SPTSSA,GALP,LINC01913" MicroRNA hsa-miR-3175:mirSVR_lowEffct hsa-miR-3175:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.74E-10 2.52E-06 1.54E-09 1.41E-08 54 1841 "ADD1,KIAA1211,WDR35,PITPNM2,MCFD2,DHX37,ASTN1,ATP12A,MYH6,ZMYM5,GLT1D1,C1orf116,AKAP6,THTPA,CLOCK,KIAA0040,CMTM5,DCAF8,EPS8L1,TSEN15,NR1H4,RB1,KIRREL1,LGR6,DHRS2,ZNF671,STK32B,F7,SLC34A2,CCDC88A,TMEM132D,C1orf112,EFR3B,MYT1L,JPH4,NAAA,NPAS3,LPIN1,GJB2,INSM2,GOLGA3,TCF7,KMT5C,KHNYN,TDG,TEP1,SLC7A8,RAB2B,RIMBP2,ATP6V0A2,NPL,HSP90B1,TECRL,LAD1" MicroRNA hsa-miR-3192:mirSVR_highEffct hsa-miR-3192:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.80E-10 2.55E-06 1.56E-09 1.42E-08 34 850 "NLN,SLAMF6,ZNF784,CARMIL3,CD84,FCRL3,PDE4D,WDFY2,POU2F1,NGDN,SNCAIP,DCAF8,PPP2R3C,DNMT3A,RASA1,KIRREL1,LGR6,ARSK,PCGF3,FNIP1,VEZT,PAICS,TADA1,WDCP,CYP1B1-AS1,CIDEB,ERAP1,KLHL20,MAST4,HMGCR,GUF1,PLB1,SDR39U1,CDK2AP1" MicroRNA hsa-miR-182:PITA hsa-miR-182:PITA_TOP PITA 4.95E-10 2.63E-06 1.60E-09 1.47E-08 25 479 "ABL2,MAP1B,ARHGAP5,STARD13,XPR1,ATAD2B,BOD1L1,CLOCK,PREPL,CEP135,PRKD1,SREK1,DMXL1,NUDT12,PARPBP,RASA1,MBNL2,PCGF3,FGF9,BRMS1L,IVNS1ABP,MYT1L,GJA3,ADGRL3,DOCK9" MicroRNA hsa-miR-99a:mirSVR_lowEffct hsa-miR-99a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.08E-10 2.70E-06 1.64E-09 1.51E-08 17 212 "MAP1B,BIRC6,CDK7,PCSK1,ZNF595,UBXN2A,GNPDA2,OGFOD2,DLEU1,NDUFAF7,LRRN2,FBXO11,NLRP2,MYO16,MEGF10,MYT1L,ERAP1" MicroRNA hsa-miR-140-3p.1:TargetScan hsa-miR-140-3p.1 TargetScan 5.16E-10 2.75E-06 1.67E-09 1.53E-08 25 480 "ARHGAP5,ATP2B4,NOVA1,CACNA1E,PKP1,RCHY1,CLOCK,PRKD1,MATR3,G3BP2,NTN4,FGF9,POTEM,MYT1L,GABRB1,HSPH1,NPFFR2,ADAM17,HMGCR,DCP2,IL6ST,ANKS1B,KCNJ9,KIF2A,PABPN1" MicroRNA hsa-miR-637:mirSVR_highEffct hsa-miR-637:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.32E-10 2.83E-06 1.72E-09 1.58E-08 28 598 "NDRG2,B4GALT3,CDK17,RGSL1,ZNF595,PGGT1B,C1orf116,CSNK1G3,ITSN2,DCAF8,SNX17,PIGG,NR1H4,ATG10,AASDH,POLR1D,SLC22A17,FLT1,CIDEB,TMEM183A,MAST4,ANO4,RIPK3,KLF12,ZNF26,CCDC169,KCNJ9,LETM1" MicroRNA hsa-miR-132:PITA hsa-miR-132:PITA_TOP PITA 5.46E-10 2.91E-06 1.76E-09 1.61E-08 21 338 "SEMA6A,NOVA1,DCLK1,CFL2,CHD1,HECTD1,HOMER1,LRRTM2,RASA1,RB1,PCGF3,SLC30A6,CCDC88A,KDM5B,RAPGEF6,ADGRL3,TFDP1,TGFBI,ATP6V0A2,SPTSSA,LOX" MicroRNA hsa-miR-212:PITA hsa-miR-212:PITA_TOP PITA 5.46E-10 2.91E-06 1.76E-09 1.61E-08 21 338 "SEMA6A,NOVA1,DCLK1,CFL2,CHD1,HECTD1,HOMER1,LRRTM2,RASA1,RB1,PCGF3,SLC30A6,CCDC88A,KDM5B,RAPGEF6,ADGRL3,TFDP1,TGFBI,ATP6V0A2,SPTSSA,LOX" MicroRNA hsa-miR-1238:mirSVR_highEffct hsa-miR-1238:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.47E-10 2.91E-06 1.76E-09 1.61E-08 17 213 "ACOX3,ZNF542P,STARD13,KCTD12,ATP7B,CSNK1G3,GALNT14,ELK3,NDUFAF7,SLC8A1,RNF17,EMILIN1,LINC01551,HEXB,PLB1,TTC41P,PABPN1" MicroRNA hsa-miR-4298:mirSVR_highEffct hsa-miR-4298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.59E-10 2.97E-06 1.80E-09 1.65E-08 32 767 "RALGAPA1,ARHGEF7,CD1E,PCDH9,PCK2,FAM177A1,RGSL1,GNPTAB,PRKD1,SNX17,OCIAD1,NR1H4,CLIP4,NTN4,ABCA11P,FCGR3A,FCGR3B,FBXO11,THADA,ZNF667,PDS5B,IQGAP2,NEDD1,TMED2,ACSL6,FCRLA,MAEL,ZNF26,MZF1,LINC00272,NPHS2,LIG4" MicroRNA hsa-miR-30c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.79E-10 3.08E-06 1.86E-09 1.71E-08 26 521 "SEMA6A,CFL2,CHD1,PGGT1B,WDFY2,PIK3C2B,POU2F1,PREPL,NCOR2,MATR3,CEP350,SACS,RASA1,FAM81B,UTP15,FOXG1,RUBCNL,N4BP2,HSPH1,STRN,TMED2,EML4,TFDP1,YTHDC2,LCP1,ZDHHC20" MicroRNA hsa-miR-502-3p:mirSVR_highEffct hsa-miR-502-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.79E-10 3.08E-06 1.86E-09 1.71E-08 26 521 "NDRG2,APAF1,AMDHD1,PCDH9,RCHY1,POU2F1,LRRTM2,DCAF8,SREK1,ARSK,CWC27,FGF9,TACC3,FTLP10,NBEA,TMEM183A,NPAS3,MRPS27,LPIN1,ZNF544,ATP11A,IL25,YTHDC2,KCNT2,KCNN2,RMST" MicroRNA "ACTTTAT,MIR-142-5P:MSigDB" "ACTTTAT,MIR-142-5P:MSigDB" MSigDB 5.83E-10 3.10E-06 1.88E-09 1.72E-08 19 274 "RALGAPA1,ULK1,CUL4A,SLC4A4,FCHO2,CDK17,SACS,EGLN3,ARGLU1,PCGF3,MBIP,ARHGEF40,ACIN1,PDS5B,ADGRL3,GRSF1,MSH6,IGF1,KIT" MicroRNA hsa-miR-627:mirSVR_highEffct hsa-miR-627:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.64E-10 3.53E-06 2.13E-09 1.95E-08 35 906 "CUL4A,EP400,ARL1,ATP4B,KCTD12,NOVA1,MPZL1,CD1D,PAH,TOGARAM2,BIVM,NUDT12,PTPRC,ATG10,IPO4,NTN4,PACRGL,UGT2A3,MARVELD2,CWC27,IRF9,UTP15,FMO1,FTLP10,SLC34A2,C1orf112,GABRA2,JPH4,NAAA,ERAP1,ATP8A2,POC5,ZNF26,FIP1L1,KIT" MicroRNA hsa-miR-675:mirSVR_lowEffct hsa-miR-675:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.72E-10 3.57E-06 2.16E-09 1.98E-08 23 412 "ARL1,AACS,CDK18,PIGR,EPN1,MPHOSPH8,POLR1D,LGR6,TCTN2,TBC1D19,PEAR1,ZNF446,SLC30A6,SLC22A4,MYO16,ATP8A2,MTUS2,C5orf56,RNF17,AP4S1,HPCAL1,ZNF10,AXDND1" MicroRNA hsa-miR-1288:mirSVR_highEffct hsa-miR-1288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.75E-10 3.59E-06 2.17E-09 1.99E-08 21 342 "BLZF1,NEDD8,POLN,TAPT1,VCAN,NOS1AP,SNX17,PTGS2,DMXL1,TINF2,SUPT7L,SMC6,CWC27,FOXO1,SLC34A2,FBXO11,NPAS3,LRCH1,ANO4,RNF212,CCDC169" MicroRNA hsa-miR-631:mirSVR_lowEffct hsa-miR-631:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.26E-10 3.86E-06 2.33E-09 2.13E-08 40 1144 "PITPNM2,SNX24,MCFD2,PPFIA4,NCOA1,NFATC4,ARHGEF7,ADGRD1,PCCA,RGSL1,PDGFRA,GLT1D1,CHD1,WDFY2,SNX6,POLN,DNM3,NUDT12,RASA1,GRTP1,SLC22A17,TOMM40L,SDC1,FOXG1,SLC34A2,ARHGEF40,CENPJ,MIMT1,TDG,NT5C1B,CRB1,LINC01551,ADAMTS19,LTB4R2,KCNJ9,DIAPH3,LAD1,LINC01913,AXDND1,PABPN1" MicroRNA hsa-miR-340*:mirSVR_highEffct hsa-miR-340*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.26E-10 3.86E-06 2.33E-09 2.13E-08 22 378 "MDM4,HOMEZ,DDX55,NOP14,AACS,DAOA,CDK7,CCDC122,ZNF595,PIGR,THAP6,POU2F1,NGDN,SNX17,SREK1,RNF4,STX2,PCBD2,SLC12A2,ITLN2,SPTSSA,NUAK2" MicroRNA "TTTGTAG,MIR-520D:MSigDB" "TTTGTAG,MIR-520D:MSigDB" MSigDB 7.30E-10 3.88E-06 2.34E-09 2.14E-08 20 310 "ADD1,ODC1,DCLK1,PDE4D,CRHBP,BIVM,COCH,ARGLU1,MBNL2,ELF1,TCTN2,PCGF3,NBEA,NR5A2,PPARGC1A,TMPO,KLF12,TRPC4,DCP2,IGF1" MicroRNA hsa-miR-3150:mirSVR_highEffct hsa-miR-3150:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.65E-10 4.07E-06 2.45E-09 2.25E-08 33 821 "NYNRIN,CUL4A,ATP2B4,B4GALT3,BCL2L2,NOVA1,PNP,NRL,CAST,CD1E,CDK18,PDE4D,CFL2,PFKFB2,AKAP6,IL20,VCAN,CEP135,NUDT12,PTPRH,GNPDA2,SNORA49,PCGF3,RELL1,CIDEB,NAAA,SRP72,GJA3,STRN,MAST4,COP1,ADAMTS19,ZNF876P" MicroRNA hsa-miR-431:mirSVR_highEffct hsa-miR-431:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.69E-10 4.09E-06 2.46E-09 2.26E-08 28 608 "ZNF542P,CD84,PCK2,JAKMIP1,POU2F1,VCAN,ITSN2,CEP135,PRKD1,ZFYVE16,SACS,TSEN15,POLR1D,TRAPPC12,CWC27,PLEKHA6,IVNS1ABP,C1orf112,LIMCH1,CIDEB,LPIN1,PSME4,METAP2,FZD10,GPN1,GUF1,LINC00272,KCNN2" MicroRNA hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 7.90E-10 4.20E-06 2.53E-09 2.32E-08 21 345 "ABL2,MAP1B,NOVA1,PDGFRA,GPR180,HECTD1,CSNK1G3,PTGS2,DNMT3A,EFS,FGF9,ARHGEF40,ATP8A2,PSME4,RASSF6,KLF12,HMGCR,GUF1,HTR2A,KIF3C,NUAK2" MicroRNA hsa-miR-6516-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.92E-10 4.21E-06 2.53E-09 2.32E-08 29 650 "SEMA6A,HOMEZ,PPP1R12B,CAD,RILPL1,CCNB1,GNPTAB,CSNK1G3,MPHOSPH8,FCRL2,F11R,MTX3,SUPT7L,TMEM33,TXNDC15,SBNO1,MARVELD2,TCTN2,STX2,CCDC38,FNIP1,BRMS1L,MRPS14,COX18,ATP6V0A2,HSP90B1,GUF1,IGF1,LMNB1" MicroRNA hsa-miR-153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.94E-10 4.22E-06 2.54E-09 2.32E-08 18 248 "SMIM14,TOGARAM2,HEATR5A,UBXN2A,DMXL1,RAN,RNASEL,SBNO1,TRAPPC13,FOXG1,SLC30A6,ZNF274,NPAS3,ZBTB37,MSH6,DCP2,SPTSSA,ZMYM2" MicroRNA hsa-miR-3130-5p:mirSVR_highEffct hsa-miR-3130-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.98E-10 4.24E-06 2.55E-09 2.33E-08 26 529 "CD84,CCNB1,PGGT1B,HOMER1,NOP9,SLC35F6,PPP2R3C,ATG10,TXNDC15,ABCA11P,FGF9,MROH9,UGGT2,OXGR1,COMMD6,TCF7,KMT5A,RNF212,CRB1,TGM1,GTF3C2,NSD2,CCDC169,ZMYM2,ZBED3-AS1,SKA3" MicroRNA hsa-miR-30b-5p:Functional MTI Functional MTI miRTarbase 8.09E-10 4.30E-06 2.58E-09 2.36E-08 23 416 "SEMA6A,MCFD2,PPP1R12B,CHD1,PGGT1B,WDFY2,PIK3C2B,PREPL,MATR3,CEP350,SACS,MBNL2,EIF2B1,FAM81B,FOXG1,RUBCNL,N4BP2,STRN,TMED2,EML4,TFDP1,LCP1,ZDHHC20" MicroRNA hsa-miR-191*:mirSVR_lowEffct hsa-miR-191*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-10 4.48E-06 2.69E-09 2.46E-08 27 570 "ADD1,ZNF784,NCOA1,SLC4A4,C1orf116,SNCAIP,WDR1,FAM129A,FAM81B,ETF1,PCGF3,FCGR3A,FCGR3B,SPON2,STPG4,TMEM132D,SLC22A5,MRPS14,CMPK2,PPARGC1A,ACTR6,GUF1,HPCAL1,NSD2,ZBED3-AS1,TTC41P,AXDND1" MicroRNA hsa-miR-186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-10 4.53E-06 2.71E-09 2.48E-08 24 454 "BCL2L2,PAH,WDR66,WDFY2,ATAD2B,TTC37,C12orf65,KLHL3,OCIAD1,RABGAP1L,SLC35F6,C14orf119,TMEM33,POLR1D,KLHL12,N4BP2L2,FOXO1,SH3BP2,PPIP5K2,GTF2H3,TXK,TMEM174,C12orf73,KIF3C" MicroRNA hsa-miR-665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.54E-10 4.54E-06 2.72E-09 2.49E-08 31 737 "MATN3,HOMEZ,APAF1,NOP14,POLE,BRI3BP,MPHOSPH8,EIF2AK2,SPATA18,MTX3,ZNF329,DTD2,RGS12,TMEM33,POLR1D,MARVELD2,TBC1D19,ARSK,CCDC38,UTP15,SH3BP2,BRMS1L,SLC30A6,KIF21B,SNRNP35,GRSF1,ATP6V0A2,HSP90B1,GUF1,IGF1,PGAM5" MicroRNA hsa-miR-30e-5p:Functional MTI Functional MTI miRTarbase 8.77E-10 4.66E-06 2.79E-09 2.56E-08 21 347 "SEMA6A,CHD1,PGGT1B,WDFY2,PIK3C2B,PREPL,PSMA6,CEP350,SACS,MBNL2,FAM81B,FOXG1,RUBCNL,N4BP2,LIMCH1,STRN,TMED2,EML4,TFDP1,LCP1,ZDHHC20" MicroRNA hsa-miR-5011-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.79E-10 4.68E-06 2.80E-09 2.56E-08 29 653 "DDX55,ATP2B4,MYBPC1,UHMK1,CFL2,NUP37,POU2F1,BRI3BP,G3BP2,SLC35F6,MBNL2,EIF2B1,ARSK,CCDC38,BRMS1L,PLEKHA6,SLC8A1,SLC12A2,SRP72,LILRB1,PPARGC1A,STRN,PPIP5K2,TECRL,NLRP8,IGF1,IL6ST,ZMYM2,LMNB1" MicroRNA hsa-miR-202*:mirSVR_highEffct hsa-miR-202*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.82E-10 4.69E-06 2.81E-09 2.57E-08 31 738 "MCC,ACOX3,CCNB1,CFAP54,HOMER1,ANAPC4,SNCAIP,CEP135,ZNF586,SPATA18,SREK1,COG3,DMXL1,BORA,VEZT,CCDC88A,MYT1L,CD244,CMPK2,NFASC,LRCH1,ERBIN,C5orf56,RNF17,ADAMTS19,ZNF26,IRF1,CHPT1,FIP1L1,IFT88,LOX" MicroRNA hsa-miR-505*:mirSVR_lowEffct hsa-miR-505*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.22E-10 4.91E-06 2.93E-09 2.69E-08 51 1715 "MDM4,BIRC6,ADD1,APAF1,DDX55,ASTN1,CBLN3,FCGR2C,FCRLB,PCCA,PDE6B,ITGBL1,THTPA,CMTM5,FCRL5,EPS8L1,SMC6,RGS12,RNF4,MPHOSPH9,LGR6,DNAJC27,SLC22A17,FCGR3A,FCGR3B,SELP,FLT1,NBEA,WDCP,SLC22A4,EFR3B,MYO16,MEGF10,ZNF274,OXGR1,NFASC,PPARGC1A,MTUS2,ADGRA3,COX18,RNF17,LINC01551,ADAMTS19,JCHAIN,ZFHX2,ZNF470,ZBED3-AS1,KIT,SLAMF9,LAD1,LCP1" MicroRNA hsa-miR-205-5p:TargetScan hsa-miR-205-5p TargetScan 9.28E-10 4.94E-06 2.95E-09 2.70E-08 23 419 "MDM4,APBB2,NCOA1,CFL2,POU2F1,LYSMD3,PREPL,DNM3,DMXL1,RAN,RNF4,ELF1,ELK3,ETF1,DLEU1,IVNS1ABP,POTEM,JPH4,KHNYN,GTF3C2,KLF12,IL6ST,IRF1" MicroRNA hsa-miR-140-5p:PITA hsa-miR-140-5p:PITA_TOP PITA 1.00E-09 5.32E-06 3.17E-09 2.91E-08 19 283 "BIRC6,HOMEZ,NCOA1,CADM3,BCL2L2,FCHO2,PDGFRA,STRN3,CSNK1G3,DNM3,FGF9,SUPT20H,ERBIN,PPARGC1A,NCSTN,RIMBP2,SLAIN1,YTHDC2,LMNB1" MicroRNA hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA_TOP PITA 1.01E-09 5.38E-06 3.21E-09 2.94E-08 24 458 "MAP1B,MCC,NCOA1,CACNA1E,XPR1,CHD1,TAPT1,PRKD1,SREK1,DHX9,F11R,G3BP2,RASA1,MBNL2,KLHL12,ETF1,PCGF3,CLIP1,FOXO1,NBEA,KDM5B,GJA3,LHX9,PABPN1" MicroRNA hsa-miR-223-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-09 5.64E-06 3.36E-09 3.08E-08 19 284 "RGS5,FAM177A1,CFL2,BRI3BP,DMXL1,SLC35F6,RGS4,PACRGL,LATS2,MBNL2,PCGF3,FNIP1,PLEKHA6,NT5C1B,TECRL,IGF1,ZFHX2,IL6ST,NT5C1B-RDH14" MicroRNA hsa-miR-515-5p:PITA hsa-miR-515-5p:PITA_TOP PITA 1.08E-09 5.72E-06 3.41E-09 3.12E-08 20 317 "ASCL1,NCOA1,SLC4A4,BCL2L2,PDGFRA,ATAD2B,POU2F1,DNM3,MATR3,G3BP2,ETF1,PDS5B,NMNAT2,KDM3B,KHNYN,XPO4,MAEL,UBE2K,ZBTB41,KIF2A" MicroRNA hsa-miR-1234:mirSVR_lowEffct hsa-miR-1234:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-09 5.92E-06 3.53E-09 3.23E-08 23 423 "SLAMF6,CDKL2,CHD1,VIT,PIGR,TAPT1,EPGN,EIF2D,TRAPPC13,SULT6B1,FGF9,BRMS1L,PLEKHA6,PPARGC1A,KMT5C,TMPO,MAEL,UBE2K,PLB1,PGAM5,ZBED3-AS1,KIR2DL4,KIR2DS4" MicroRNA hsa-miR-493:mirSVR_highEffct hsa-miR-493:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-09 5.95E-06 3.54E-09 3.24E-08 29 660 "RALGAPA1,ADD1,KIAA1211,SLAMF6,ZNF784,CENPBD1P1,FCRLB,PCK2,PDGFRA,POU2F1,LYSMD3,SPATA18,PSME1,GNPDA2,LATS2,RNF4,ABCA11P,GMPR2,IRF9,RELL1,NUBPL,LPIN1,LILRB4,KCNT2,MZF1,TDRD3,KCNJ9,KIT,LMNB1" MicroRNA hsa-miR-602:mirSVR_lowEffct hsa-miR-602:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-09 6.04E-06 3.59E-09 3.29E-08 26 538 "RGS5,DDX55,CENPBD1P1,ATP2B4,CADM3,ARHGEF7,CD1E,CDK18,PDGFRA,MATR3,TBC1D4,B3GLCT,TMEM33,RNF4,ADGRV1,SDC1,STAB2,ZNF446,P2RX2,NR5A2,MYO16,ERAP1,MTUS2,DOCK9,SPRYD7,LMNB1" MicroRNA hsa-miR-412:mirSVR_highEffct hsa-miR-412:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-09 6.08E-06 3.62E-09 3.31E-08 30 703 "MDM4,ADD1,NCOA1,B4GALT3,PCCA,RGSL1,GLT1D1,ADGRF3,THAP6,SNCAIP,SNX17,RABGAP1L,RNF219,NTN4,MBNL2,DRAM1,PCGF3,GOLGA2P5,CENPJ,NPAS3,DRC1,PSME4,ADAM17,GOLGA3,C1QTNF9B,RNF17,TECRL,HPCAL1,CCDC169,DNAH10" MicroRNA hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.15E-09 6.12E-06 3.64E-09 3.33E-08 24 461 "MAP1B,ULK1,BCL2L2,CCNA1,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,LATS2,SBNO1,MBNL2,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-6499-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-09 6.35E-06 3.77E-09 3.45E-08 34 881 "ABL2,HOMEZ,PPP1R12B,CAD,CDKL2,RILPL1,CCNB1,MRPL57,GNPTAB,HEATR5A,MPHOSPH8,FCRL2,F11R,MTX3,SUPT7L,TMEM33,POLR1D,TXNDC15,SBNO1,MARVELD2,TCTN2,STX2,CCDC38,FNIP1,VEZT,BRMS1L,MRPS14,COX18,TEP1,ATP6V0A2,HSP90B1,GUF1,IGF1,IRF1" MicroRNA hsa-miR-217:PITA hsa-miR-217:PITA_TOP PITA 1.20E-09 6.37E-06 3.78E-09 3.46E-08 20 319 "SEMA6A,SLC4A4,NOVA1,RILPL1,ATAD2B,BOD1L1,HOMER1,MPHOSPH9,FBXO11,SLC30A6,PDS5B,PCDH17,ADGRL3,KMT5A,XPO4,TDG,KLF12,UBE2K,TMEM178A,KIF3C" MicroRNA hsa-miR-345:mirSVR_highEffct hsa-miR-345:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-09 6.53E-06 3.87E-09 3.54E-08 26 540 "MDM4,PNP,FCHO2,UHMK1,TOGARAM2,F11R,RAN,ADGRV1,TM9SF1,THADA,GABRA2,NAAA,ATP8A2,LINC02393,ADGRL3,TGFBI,TGM1,AP4S1,MAEL,GPN1,ZBED3-AS1,CHPT1,TTC41P,RMST,NUAK2,AXDND1" MicroRNA hsa-miR-142-3p:Functional MTI Functional MTI miRTarbase 1.24E-09 6.58E-06 3.90E-09 3.57E-08 22 389 "RGS5,MCFD2,APC,KCTD12,FAM177A1,HECTD1,STRN3,COPA,CLOCK,CSNK1G3,SLC35F6,STX2,SUCO,BRMS1L,SLC30A6,PSME4,EML4,HSD17B4,NSD2,IL6ST,IRF1,LOX" MicroRNA hsa-miR-517a:mirSVR_lowEffct hsa-miR-517a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-09 6.67E-06 3.95E-09 3.62E-08 21 354 "APBB2,CDK17,PDE4D,LYSMD3,GALNT9,MATR3,PTPRH,RB1,OGFOD2,RGS12,LRPPRC,EFNA5,DLEU1,F7,FLT1,IVNS1ABP,SLC12A2,SLC15A4,PPIP5K2,ATP6V0A2,CDK2AP1" MicroRNA hsa-miR-1277-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-09 7.26E-06 4.30E-09 3.93E-08 28 624 "DDX55,ATP2B4,MYBPC1,UHMK1,FAM177A1,CFL2,NUP37,POU2F1,BRI3BP,UBXN2A,COCH,G3BP2,SLC35F6,EIF2B1,CCDC38,BRMS1L,PLEKHA6,SRP72,PPARGC1A,STRN,PPIP5K2,DOCK9,RASSF6,GUF1,NLRP8,IGF1,IL6ST,ZMYM2" MicroRNA hsa-miR-513b:PITA hsa-miR-513b:PITA_TOP PITA 1.49E-09 7.90E-06 4.67E-09 4.28E-08 20 323 "APC,NCOA1,CENPC,ATAD2B,THAP6,AKAP6,CSNK1G3,SREK1,CEP350,ARGLU1,USP44,IVNS1ABP,MYT1L,PDS5B,SRP72,PCDH17,EML4,GTF3C2,ADAMTS19,ZBTB41" MicroRNA hsa-miR-542-3p:TargetScan hsa-miR-542-3p TargetScan 1.49E-09 7.94E-06 4.70E-09 4.30E-08 18 258 "MAP1B,APBB2,PPP1R12B,NOVA1,NRL,CAMK4,PDE4D,PIGR,RCHY1,PLEKHA6,ATP8A2,PCDH17,GRSF1,MSH6,GTF3C2,ATP6V0A2,KLF12,IRF1" MicroRNA hsa-miR-27b*:mirSVR_highEffct hsa-miR-27b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-09 8.35E-06 4.94E-09 4.52E-08 28 628 "DDX55,BLZF1,NOP14,ATP2B4,LINC02347,PNP,SLC5A8,CDK17,LINC01085,ATAD2B,ADGRF3,PREPL,FCRL5,SREK1,RGS4,CLIP4,RELL1,FOXO1,THADA,SLC12A2,MRPS14,LIMCH1,NAAA,MAST4,CNTN2,TDG,ZNF10,LHX9" MicroRNA hsa-miR-483-5p:mirSVR_lowEffct hsa-miR-483-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-09 8.80E-06 5.20E-09 4.76E-08 33 847 "NDRG2,SLAMF6,NOP14,CADM3,RAB29,FAM177A1,NRXN1,TAPT1,COPA,HEATR5A,C12orf65,FCRL2,BIVM,SLC35F6,FAM129A,REST,CLIP4,GP6,DNAJC27,CLIP1,SPON2,DDX51,NUBPL,ZNF605,N4BP2,EFR3B,METAP2,LINC01551,TMPO,NPL,IRF1,LHX9,AXDND1" MicroRNA hsa-miR-370:mirSVR_highEffct hsa-miR-370:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.70E-09 9.04E-06 5.34E-09 4.89E-08 27 589 "MDM4,SLAMF6,CDKL4,FAM193A,CENPBD1P1,SLC4A4,ARHGEF7,LINC02347,PNP,RILPL1,THTPA,UBXN2A,FCRL2,PTPRC,EGLN3,NTN4,SETDB2,LATS2,EIF2B1,DLEU1,SULT6B1,UFM1,TADA1,TMEM183A,ZBTB37,TPO,RMST" MicroRNA hsa-miR-4301:mirSVR_highEffct hsa-miR-4301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-09 9.14E-06 5.39E-09 4.94E-08 22 396 "SNX24,CD1E,FAM177A1,SCFD2,CFL2,BRI3BP,SREK1,TSEN15,BORA,EFS,VEZT,CCDC88A,ZNF605,NPAS3,RBKS,METAP2,KMT5A,AP4S1,POC5,ZNF10,CENPH,FAM71C" MicroRNA hsa-miR-135a*:mirSVR_highEffct hsa-miR-135a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-09 9.23E-06 5.45E-09 4.99E-08 29 673 "BLZF1,ARHGAP5,ASCL1,SLC4A4,ITGBL1,CFAP54,PRKD1,SPATA18,CEP120,PARPBP,RGS4,LRPPRC,RNASEL,ZNF219,F7,ELOVL7,VEZT,MRPS14,PPARGC1A,PPIP5K2,TGFBI,RAB2B,TMPO,CCDC169,PLB1,CCDC190,LHX9,LCP1,LOX" MicroRNA "ACCAAAG,MIR-9:MSigDB" "ACCAAAG,MIR-9:MSigDB" MSigDB 1.76E-09 9.33E-06 5.50E-09 5.04E-08 24 471 "MAP1B,CUL4A,NCOA1,STARD13,KCTD12,CLOCK,NCOR2,KLHL3,SACS,IPO4,ELF1,MAEA,FOXG1,NR5A2,NFASC,ERBIN,ATP11A,DOCK9,GRSF1,TGFBI,KLF12,NSD2,SPTSSA,ZBTB41" MicroRNA hsa-miR-4317:mirSVR_highEffct hsa-miR-4317:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-09 9.56E-06 5.63E-09 5.15E-08 26 550 "LRRC43,ARHGEF7,ZMYM5,PDE4D,GLT1D1,CCDC122,UGT2B28,THAP6,LACC1,FBXL5,DEPDC4,SLC8A1,SLC12A2,PDS5B,CMPK2,RBKS,PPARGC1A,MAST4,MTUS2,ACSL6,RIMBP2,UGT2B7,CHPT1,FIP1L1,DNAH10,AXDND1" MicroRNA hsa-miR-544b:mirSVR_highEffct hsa-miR-544b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-09 9.56E-06 5.63E-09 5.15E-08 26 550 "NDRG2,AP1G2,CAST,GLT1D1,VIT,ITGBL1,PIGR,CFAP45,SNCAIP,DMXL1,TINF2,NR1H4,SMC6,CLIP4,MPHOSPH9,DNAJC27,ARL6IP4,BRMS1L,ZNF667,PUS1,CRB1,SLC7A8,GZMH,FCRL6,KIR2DL4,AXDND1" MicroRNA hsa-miR-576-5p:PITA hsa-miR-576-5p:PITA_TOP PITA 1.82E-09 9.66E-06 5.68E-09 5.20E-08 23 434 "MCC,RGS5,ARHGAP5,SLC4A4,FCHO2,ITGBL1,NRXN1,SMIM14,ATAD2B,EPN1,DMXL1,CEP350,SMC6,MEMO1,POLR1D,TBC1D19,SUCO,MYT1L,KLHL20,PCDH17,RIMBP2,IGF1,DNAH10" MicroRNA hsa-miR-4283:mirSVR_lowEffct hsa-miR-4283:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-09 9.74E-06 5.73E-09 5.24E-08 43 1332 "LRRC43,ADORA1,TBC1D14,STARD13,PPP1R12B,FGFRL1,CCNA1,CAST,CDK17,COLEC11,PIGR,PKP1,NGDN,ITSN2,FCRL2,SPATA18,DGKQ,OCIAD1,WDR1,PARPBP,RNF31,STK32B,F7,SPON2,FOXO1,PLEKHA6,CCDC88A,YPEL5,UGGT2,LIMCH1,DCAF11,KMT5C,NCSTN,TFDP1,AP4S1,ADAMTS19,FCRL6,ZMYM2,LINC00272,KCNN2,CAB39L,LINC01913,PABPN1" MicroRNA hsa-miR-340*:mirSVR_lowEffct hsa-miR-340*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-09 9.89E-06 5.81E-09 5.32E-08 32 806 "ADORA1,UVSSA,APAF1,WDR19,CENPBD1P1,CARMIL3,SLC5A6,PIK3C2B,GNPTAB,MPHOSPH8,FCRL2,ZFYVE16,BIVM,F11R,SLC35F6,FAM129A,RGS12,DCUN1D2,ARL6IP4,UTP15,RELL1,FTLP10,SLC30A6,THADA,MCCC2,COMMD6,NCSTN,ZBTB49,CENPH,ZBED3-AS1,FIP1L1,SPATA13" MicroRNA hsa-miR-144:PITA hsa-miR-144:PITA_TOP PITA 1.90E-09 1.01E-05 5.92E-09 5.42E-08 27 592 "MAP1B,NLN,SEMA6A,ARHGAP5,ASCL1,NFXL1,PDE4D,CFL2,PGGT1B,GNPTAB,ITSN2,CEP135,SREK1,ARGLU1,MBNL2,TBC1D19,ETF1,FOXG1,FOXO1,CCDC88A,SLC12A2,MYT1L,PPARGC1A,STRN,ATP11A,ZBTB41,PABPN1" MicroRNA hsa-miR-136-5p:TargetScan hsa-miR-136-5p TargetScan 1.91E-09 1.01E-05 5.94E-09 5.44E-08 18 262 "NYNRIN,MPZL1,DMXL1,OCIAD1,RABGAP1L,RABGGTA,DNMT3A,RGS4,DRAM1,ETF1,PCBD2,NUBPL,MRPS14,NPAS3,PPARGC1A,PSME4,HAL,DCP2" MicroRNA hsa-miR-1244:PITA hsa-miR-1244:PITA_TOP PITA 1.91E-09 1.01E-05 5.94E-09 5.44E-08 18 262 "BIRC6,CADM3,NOVA1,ZNF664,DCLK1,CDK17,G3BP2,MTX3,DNMT3A,RASA1,TMEM161B,USP44,FBXO11,GJA3,EML4,MAEL,KLF12,SPTSSA" MicroRNA hsa-miR-27a*:mirSVR_lowEffct hsa-miR-27a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.95E-09 1.03E-05 6.06E-09 5.55E-08 38 1087 "ADD1,COG6,PITPNM2,PPFIA4,MSH2,FAM193A,NCOA1,CENPBD1P1,FGFRL1,BCL2L2,AP1G2,LINC02347,PAH,GPR180,NGDN,CSNK1G3,LRRTM2,FCRL5,ATG10,RGS12,ELK3,MPHOSPH9,SAP18,NDUFAF7,FLT1,CGREF1,IQGAP2,MIMT1,ZBTB37,BRD8,STON1,RNF17,HTR2A,TADA2B,KCNJ9,KCNN2,DIAPH3,PABPN1" MicroRNA hsa-miR-615-5p:mirSVR_lowEffct hsa-miR-615-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-09 1.05E-05 6.14E-09 5.62E-08 36 992 "SFTA3,ADORA1,SEMA6A,CUL4A,KCTD12,ARHGEF7,SLC5A6,ADGRD1,CAST,LDB2,CD1E,PITX1,EPN1,TOGARAM2,LYSMD3,FCRL5,NOS1AP,SLC35F6,GALNT14,RNF31,FAM228A,RGS12,GP6,F10,TMEM129,RUBCNL,TMEM175,UFM1,CYP1B1-AS1,IKBIP,MIMT1,MAST4,NCSTN,NPL,ADAMTS19,ZAR1L" MicroRNA hsa-miR-4292:mirSVR_highEffct hsa-miR-4292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-09 1.05E-05 6.15E-09 5.63E-08 22 399 "ARL1,CARMIL3,RILPL1,SNCAIP,C12orf65,PSME1,RABGAP1L,RNF219,DNMT3A,ARGLU1,GUSBP3,NBEA,CCDC88A,GABRB1,KDM3B,SRP72,GC,TDG,MAEL,ARHGAP30,LHX9,PABPN1" MicroRNA hsa-miR-125b:mirSVR_highEffct hsa-miR-125b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.98E-09 1.05E-05 6.16E-09 5.64E-08 23 436 "HOMEZ,BLZF1,STARD13,CD84,LINC02347,CHAMP1,POU2F1,RABGAP1L,GALNT14,FAM129A,RB1,TMEM161B,MEMO1,CGREF1,CD244,NPL,CCDC169,ZBED3-AS1,KCNN2,AXDND1,LIG4,LMNB1,IFT88" MicroRNA hsa-miR-4319:mirSVR_highEffct hsa-miR-4319:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-09 1.05E-05 6.16E-09 5.64E-08 23 436 "HOMEZ,BLZF1,STARD13,LINC02347,CHAMP1,POU2F1,RABGAP1L,GALNT14,FAM129A,RB1,TMEM161B,MEMO1,CGREF1,CD244,TDG,NPL,CCDC169,ZBED3-AS1,KCNN2,AXDND1,LIG4,LMNB1,IFT88" MicroRNA hsa-miR-1261:PITA hsa-miR-1261:PITA_TOP PITA 2.02E-09 1.08E-05 6.28E-09 5.75E-08 17 232 "PCDH9,CFL2,HOMER1,STRN3,SUPT7L,RGS4,LATS2,NBEA,CCDC92,CCDC88A,KDM5B,GJB6,KDM3B,ERBIN,METAP2,ADAMTS19,NSD2" MicroRNA "CATTTCA,MIR-203:MSigDB" "CATTTCA,MIR-203:MSigDB" MSigDB 2.15E-09 1.14E-05 6.68E-09 6.11E-08 18 264 "APC,SLC4A4,NOVA1,PCSK1,PDE4D,FAM228A,MBNL2,FOXG1,NBEA,SLC12A2,LIMCH1,NMNAT2,LPIN1,PSME4,XPO4,KLF12,C12orf73,SPTSSA" MicroRNA "GCACTTT,MIR-106A:MSigDB" "GCACTTT,MIR-106A:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA "GCACTTT,MIR-106B:MSigDB" "GCACTTT,MIR-106B:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA "GCACTTT,MIR-20B:MSigDB" "GCACTTT,MIR-20B:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA "GCACTTT,MIR-519D:MSigDB" "GCACTTT,MIR-519D:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA "GCACTTT,MIR-17-5P:MSigDB" "GCACTTT,MIR-17-5P:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA "GCACTTT,MIR-20A:MSigDB" "GCACTTT,MIR-20A:MSigDB" MSigDB 2.17E-09 1.15E-05 6.71E-09 6.15E-08 26 555 "ULK1,APBB2,ATP1A2,BCL2L2,FCHO2,PDGFRA,CFL2,CLOCK,DCAF8,FBXL5,SACS,EGLN3,RB1,NTN4,ELK3,DNAJC27,SUCO,FLT1,NBEA,BRMS1L,MYT1L,NPAS3,KLHL20,KLF12,IRF1,ZBTB41" MicroRNA hsa-miR-450b-3p:mirSVR_highEffct hsa-miR-450b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-09 1.20E-05 6.96E-09 6.37E-08 26 556 "KIAA1211,SLAMF6,NOVA1,FCGR2C,GPR180,SNCAIP,GLT8D2,COG3,CLIP4,RNASE2,ELF1,POLK,CCDC92,LIMCH1,NAAA,ANKLE2,TMED2,ADAM17,C5orf56,GTF3C2,HSP90B1,HPCAL1,LINC00272,RMST,AXDND1,PABPN1" MicroRNA hsa-miR-6778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-09 1.20E-05 7.00E-09 6.41E-08 29 681 "ABL2,SMIM15,SLC4A4,THAP6,STRN3,POU2F1,CEP135,PIGG,OCIAD1,RABGAP1L,SLC35F6,C14orf119,ZNF419,EFNA5,DCUN1D2,FCAR,VEZT,ZCCHC8,BRMS1L,UGGT2,UTP20,SPIC,ACSL6,NT5C1B,GTF2H3,RASSF6,TXK,FAM151B,NT5C1B-RDH14" MicroRNA hsa-miR-4318:mirSVR_highEffct hsa-miR-4318:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.34E-09 1.24E-05 7.22E-09 6.61E-08 29 682 "MCC,STARD13,TAF1B,FCHO2,FCGR2C,PCDH9,PDGFRA,NRXN1,BRI3BP,DCAF8,COG3,DMXL1,DHX9,DCUN1D2,PAICS,SLC12A2,MYO16,ZNF274,KDM3B,ANO4,AP4S1,MAEL,VRK2,ANKS1B,LINC00272,CHPT1,KIR2DL1,TTC41P,AXDND1" MicroRNA hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA_TOP PITA 2.35E-09 1.25E-05 7.25E-09 6.64E-08 19 298 "ABL2,MCFD2,NOVA1,DCLK1,CDK17,PDGFRA,CFL2,ATAD2B,KLHL3,G3BP2,DNMT3A,RB1,TMEM161B,CCDC88A,IQGAP2,EML4,RIMBP2,KLF12,TMEM178A" MicroRNA hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA_TOP PITA 2.35E-09 1.25E-05 7.25E-09 6.64E-08 19 298 "ABL2,MCFD2,NOVA1,DCLK1,CDK17,PDGFRA,CFL2,ATAD2B,KLHL3,G3BP2,DNMT3A,RB1,TMEM161B,CCDC88A,IQGAP2,EML4,RIMBP2,KLF12,TMEM178A" MicroRNA hsa-miR-30d-5p:Functional MTI Functional MTI miRTarbase 2.50E-09 1.33E-05 7.71E-09 7.06E-08 21 368 "MAP1B,SEMA6A,KCTD12,CHD1,PGGT1B,WDFY2,PIK3C2B,PREPL,CEP350,SACS,FAM81B,FNIP1,FOXG1,RUBCNL,N4BP2,STRN,TMED2,EML4,TFDP1,LCP1,ZDHHC20" MicroRNA hsa-miR-338-3p:TargetScan hsa-miR-338-3p TargetScan 2.50E-09 1.33E-05 7.72E-09 7.06E-08 20 333 "ADORA1,BCL2L2,NOVA1,FAM169A,F11R,DNMT3A,RASA1,ARGLU1,EFNA5,KLHL12,PCGF3,F10,PCBD2,DCAF11,MYT1L,ADAM17,MSH6,IGF1,KIF2A,LTA4H" MicroRNA hsa-miR-3130-3p:mirSVR_highEffct hsa-miR-3130-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-09 1.37E-05 7.91E-09 7.24E-08 23 442 "HOMEZ,PPP1R12B,CD84,HECTD1,DCAF8,MATR3,COG3,DMXL1,OGFOD2,POLR1D,LGR6,ABCA11P,RASA3,LIMCH1,TMEM183A,LPIN1,TFDP1,ZNF721,TNR,ADAMTS19,ZNF876P,FAM71C,IFT88" MicroRNA hsa-miR-650:mirSVR_highEffct hsa-miR-650:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.72E-09 1.45E-05 8.37E-09 7.66E-08 30 730 "DDX55,STXBP6,NCOA1,BCL2L2,CACNA1E,CDK18,CFL2,CPNE6,PIK3C2B,FAM53A,CSNK1G3,VCAN,ITSN2,SPATA18,SLC9C2,RNF4,LGR6,ARSK,TLR6,SUCO,BRMS1L,THADA,CIDEB,JPH4,TMED2,NCSTN,RAB2B,LINC01913,AXDND1,CDK2AP1" MicroRNA "TTTGCAC,MIR-19B:MSigDB" "TTTGCAC,MIR-19B:MSigDB" MSigDB 2.87E-09 1.53E-05 8.82E-09 8.08E-08 24 483 "PITPNM2,ARHGAP5,CAST,PITX1,CLOCK,SNX17,G3BP2,WDR1,ARGLU1,MBNL2,ELK3,MPHOSPH9,SDC1,NBEA,IVNS1ABP,CCDC88A,KLHL20,ATP11A,GRSF1,RAB2B,TENT2,IGF1,SPTSSA,KIT" MicroRNA "TTTGCAC,MIR-19A:MSigDB" "TTTGCAC,MIR-19A:MSigDB" MSigDB 2.87E-09 1.53E-05 8.82E-09 8.08E-08 24 483 "PITPNM2,ARHGAP5,CAST,PITX1,CLOCK,SNX17,G3BP2,WDR1,ARGLU1,MBNL2,ELK3,MPHOSPH9,SDC1,NBEA,IVNS1ABP,CCDC88A,KLHL20,ATP11A,GRSF1,RAB2B,TENT2,IGF1,SPTSSA,KIT" MicroRNA hsa-miR-1252:PITA hsa-miR-1252:PITA_TOP PITA 2.88E-09 1.53E-05 8.86E-09 8.12E-08 21 371 "SEMA6A,NCOA1,MPZL1,XPR1,CDK17,AKAP6,STRN3,DNM3,CEP350,ARGLU1,ELK3,FBXO11,NBEA,MYT1L,SRP72,PCDH17,ADGRL3,TCF7,MAEL,NSD2,FAM49A" MicroRNA hsa-miR-617:mirSVR_highEffct hsa-miR-617:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.01E-09 1.60E-05 9.24E-09 8.46E-08 28 647 "ACOX3,COG6,BLZF1,LINC02347,PCDH9,PDGFRA,CFAP54,EPGN,FCRL2,PIGG,SREK1,CEP350,TINF2,G3BP2,PACRGL,ARSK,ADGRV1,GORAB,FOXG1,ARHGEF40,UGGT2,CENPJ,UHRF1BP1L,ANO4,DOCK9,AP4S1,STARD4,RMST" MicroRNA hsa-miR-204-5p:TargetScan hsa-miR-204-5p TargetScan 3.13E-09 1.67E-05 9.62E-09 8.81E-08 26 565 "MAP1B,MCC,BIRC6,ARHGAP5,BCL2L2,NOVA1,PIK3C2B,NGDN,NOS1AP,DCAF8,PSME1,RABGAP1L,DTD2,CLIP4,EFNA5,PCGF3,FNIP1,FLT3,NBEA,MYT1L,HSPH1,NPAS3,PPARGC1A,KLF12,ARHGAP30,HMGCR" MicroRNA hsa-miR-211-5p:TargetScan hsa-miR-211-5p TargetScan 3.13E-09 1.67E-05 9.62E-09 8.81E-08 26 565 "MAP1B,MCC,BIRC6,ARHGAP5,BCL2L2,NOVA1,PIK3C2B,NGDN,NOS1AP,DCAF8,PSME1,RABGAP1L,DTD2,CLIP4,EFNA5,PCGF3,FNIP1,FLT3,NBEA,MYT1L,HSPH1,NPAS3,PPARGC1A,KLF12,ARHGAP30,HMGCR" MicroRNA hsa-miR-501-3p:mirSVR_highEffct hsa-miR-501-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.60E-09 1.91E-05 1.10E-08 1.01E-07 23 450 "APAF1,AMDHD1,FCHO2,PCDH9,RCHY1,POU2F1,LRRTM2,DCAF8,SREK1,ARSK,CWC27,FGF9,FTLP10,NBEA,TMEM183A,NPAS3,MRPS27,LPIN1,ZNF544,ATP11A,IL25,YTHDC2,KCNT2" MicroRNA "TTGCCAA,MIR-182:MSigDB" "TTGCCAA,MIR-182:MSigDB" MSigDB 3.63E-09 1.93E-05 1.11E-08 1.02E-07 19 306 "STARD13,ARHGEF7,XPR1,CLOCK,PREPL,PRKD1,DMXL1,RASA1,ARGLU1,MBNL2,PCGF3,FGF9,BRMS1L,NFASC,PCDH17,DOCK9,RIMBP2,NSD2,SELENOI" MicroRNA hsa-miR-210:mirSVR_lowEffct hsa-miR-210:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.65E-09 1.94E-05 1.12E-08 1.02E-07 24 489 "ADD1,COG6,ULK1,ASCL1,FGFRL1,PROZ,WDFY2,DNM3,NOS1AP,DGKQ,COG3,GNPDA2,ARSK,MAEA,F7,UTP15,MYO16,MYT1L,GABRB1,RNF212,ZBTB49,NSD2,PGAM5,KIR2DL4" MicroRNA hsa-miR-1243:PITA hsa-miR-1243:PITA_TOP PITA 3.67E-09 1.95E-05 1.12E-08 1.03E-07 14 155 "MAP1B,BIRC6,SLC4A4,PCDH9,ATAD2B,COG3,CEP350,MBNL2,SUCO,PPARGC1A,METAP2,GRSF1,ADAMTS19,IGF1" MicroRNA hsa-miR-604:mirSVR_lowEffct hsa-miR-604:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.99E-09 2.12E-05 1.22E-08 1.12E-07 25 531 "MSH2,NCOA1,ODC1,DCLK1,CHD1,CFAP54,COPA,NCOR2,RNF31,OGFOD2,IPO4,TXNDC15,F10,NDUFAF7,POLK,G2E3,NBEA,LRCH1,TECRL,GUF1,HPCAL1,ZNF324B,PLB1,ANKS1B,LHX9" MicroRNA hsa-miR-4323:mirSVR_highEffct hsa-miR-4323:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.05E-09 2.15E-05 1.24E-08 1.13E-07 22 415 "ADD1,CUL4A,B4GALT3,CHAMP1,PCDH9,SMIM14,THAP6,FAM169A,CMTM5,BIVM,GALNT14,FAM172A,ETF1,SH3YL1,UHRF1BP1L,NEDD1,INSM2,ANO4,STON1,TGFBI,PLB1,RMST" MicroRNA hsa-miR-598:mirSVR_lowEffct hsa-miR-598:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.08E-09 2.17E-05 1.25E-08 1.14E-07 23 453 "SEMA6A,NFKBIA,PDGFRA,ITGBL1,HOMER1,C1orf116,FCRL5,BIVM,LOC439933,C14orf119,ARGLU1,ELK3,TRAPPC13,POLK,SLC12A2,EFR3B,ERAP1,PPIP5K2,MTUS2,ANO4,WDR36,FAM151B,AXDND1" MicroRNA hsa-miR-1264:PITA hsa-miR-1264:PITA_TOP PITA 4.08E-09 2.17E-05 1.25E-08 1.14E-07 23 453 "BIRC6,SEMA6A,NRXN1,HOMER1,PTGS2,G3BP2,RABGAP1L,FGF9,SUCO,FBXO11,PLEKHA6,IVNS1ABP,MYT1L,NFASC,DOCK9,XPO4,GRSF1,GPN1,KCNT2,ZBTB41,LHX9,KCNN2,NUAK2" MicroRNA hsa-miR-3689a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-09 2.23E-05 1.28E-08 1.17E-07 28 657 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-3689c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-09 2.23E-05 1.28E-08 1.17E-07 28 657 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-3689b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-09 2.23E-05 1.28E-08 1.17E-07 28 657 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-34b:PITA hsa-miR-34b:PITA_TOP PITA 4.20E-09 2.23E-05 1.28E-08 1.17E-07 21 379 "CAMK4,ZNF664,CDK17,PDE4D,CFL2,CHD1,ATAD2B,DHX9,LATS2,MBNL2,FOXG1,ZCCHC8,MYT1L,PDS5B,PCDH17,STRN,PSME4,ADGRL3,IGF1,ZNF470,KIF2A" MicroRNA hsa-miR-130b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.35E-09 2.31E-05 1.32E-08 1.21E-07 20 344 "ASCL1,MYBPC1,CD84,SYT2,CHD1,PIK3C2B,NUP37,UGT2B28,NCOR2,PIGG,SREK1,ATG10,ATP6AP1L,FOXO1,PLEKHA6,N4BP2,RAPGEF6,XPO4,IGF1,LHX9" MicroRNA hsa-miR-150-5p:Functional MTI Functional MTI miRTarbase 4.46E-09 2.37E-05 1.36E-08 1.24E-07 25 534 "CAMK4,CAST,XPR1,WDFY2,PIGR,ATAD2B,THAP6,C12orf65,CEP135,OCIAD1,RABGAP1L,SLC35F6,C14orf119,TMEM33,DLEU1,N4BP2L2,FLT3,RAPGEF6,MRPS27,SPIC,ACSL6,TEP1,GTF2H3,TXK,TMEM174" MicroRNA hsa-miR-1273h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-09 2.38E-05 1.36E-08 1.25E-07 28 659 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-487a:PITA hsa-miR-487a:PITA_TOP PITA 4.60E-09 2.45E-05 1.40E-08 1.28E-07 17 245 "ASTN1,STARD13,MPZL1,FCHO2,LDB2,PDE4D,SNX6,PIK3C2B,BOD1L1,CLOCK,LRRTM2,CEP350,LATS2,DEPDC4,FGF9,PPARGC1A,ZNF470" MicroRNA hsa-miR-1909:mirSVR_lowEffct hsa-miR-1909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.61E-09 2.45E-05 1.40E-08 1.28E-07 53 1911 "ABL2,MDM4,SLAMF6,SNX24,DHX37,ASCL1,BCL2L2,NFATC4,CDK18,ZNF595,PTPRVP,FAM163A,COPA,TOGARAM2,EPS8L1,RNF31,OGFOD2,RNASEL,GRTP1,EFS,PCGF3,SLC22A17,TOMM40L,TACC3,PIBF1,STAB2,PLEKHA6,STPG4,ACIN1,UGGT2,CYP1B1-AS1,NAAA,LPIN1,LILRB4,KMT5C,DOCK9,GTF3C2,RIMBP2,NPL,HEXB,PAPPA2,IGF1,TADA2B,C12orf73,FAM151B,KIR2DL1,KIR2DS4,KIR3DL1,KIR3DL2,LINC00442,NUAK2,TTC7A,SPATA13" MicroRNA hsa-miR-6780a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-09 2.46E-05 1.41E-08 1.29E-07 28 660 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-33b*:mirSVR_highEffct hsa-miR-33b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.82E-09 2.56E-05 1.46E-08 1.34E-07 26 577 "MATN3,EP400,ATP1A2,LINC02347,PCCA,RCBTB2,THAP6,AKAP6,MPC2,EPGN,CLOCK,LACC1,BORA,SUCO,FTLP10,RUBCNL,NUBPL,UFM1,SCYL2,TMEM183A,DOCK9,NT5C1B,LINC01551,NPL,FAM151B,SPRYD7" MicroRNA hsa-miR-519e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.87E-09 2.59E-05 1.48E-08 1.35E-07 15 186 "POLE,POU2F1,HEATR5A,PRKD1,FAM129A,MPHOSPH9,PCBD2,FCGR3B,POTEM,KDM5B,KDM3B,ZNF544,ADAM17,TGFBI,C12orf73" MicroRNA hsa-miR-24-2*:mirSVR_highEffct hsa-miR-24-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.04E-09 2.68E-05 1.53E-08 1.40E-07 20 347 "COG6,AMDHD1,CHAMP1,PCDH9,LINC01257,FAM129A,ATG10,REST,FGF9,TNFRSF19,TMEM183A,ERBIN,DOCK9,TECRL,IGF1,ZNF470,ZMYM2,FAM151B,ZBED3-AS1,NUAK2" MicroRNA hsa-miR-145-5p:TargetScan hsa-miR-145-5p TargetScan 5.10E-09 2.71E-05 1.55E-08 1.42E-07 28 663 "ATP1A2,MPZL1,RILPL1,SCARB1,PCDH9,CFL2,ATAD2B,EPN1,HECTD1,BRI3BP,EIF2AK2,MTX3,DNMT3A,RASA1,NTN4,ELK3,MARVELD2,CLIP1,FOXO1,FLT1,IVNS1ABP,POTEM,ADAM17,PPIP5K2,DOCK9,NCSTN,HTR2A,LOX" MicroRNA hsa-miR-27b-3p:Functional MTI Functional MTI miRTarbase 5.25E-09 2.79E-05 1.59E-08 1.46E-07 22 421 "ABL2,MAP1B,ADD1,KIAA1211,NLN,SEMA6A,KCTD12,ATP7B,SLC5A6,LYSMD3,ITSN2,TOMM40L,SUCO,FOXO1,WDCP,MRPS14,NR5A2,MRPS27,ZBTB37,LPIN1,CAB39L,SPATA13" MicroRNA hsa-miR-7977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.27E-09 2.80E-05 1.59E-08 1.46E-07 28 664 "MATN3,APAF1,MPZL1,RILPL1,PDE6B,CCDC122,GPR180,STRN3,POU2F1,NOS1AP,SPATA18,MARVELD2,ARSK,PCBD2,SH3BP2,BRMS1L,UHRF1BP1L,GOLGA3,COX18,GRSF1,TGFBI,ATP6V0A2,GUF1,IGF1,ZNF324B,PGAM5,FAM151B,ZDHHC20" MicroRNA hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA_TOP PITA 5.28E-09 2.81E-05 1.60E-08 1.46E-07 21 384 "KCTD12,NEDD8,FCHO2,UHMK1,PDE4D,FBXL5,KLHL3,TBC1D4,G3BP2,B3GLCT,FNIP1,SUCO,SCYL2,MYT1L,PDS5B,ERBIN,PPARGC1A,ATP11A,ADGRL3,SLAIN1,ZMYM2" MicroRNA hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 5.43E-09 2.89E-05 1.64E-08 1.50E-07 23 460 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,MBNL2,IRF9,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-199a-5p:TargetScan hsa-miR-199a-5p TargetScan 5.48E-09 2.92E-05 1.66E-08 1.52E-07 22 422 "RALGAPA1,MCFD2,ATP1A2,PNP,PDE4D,GPR180,LYSMD3,CLOCK,PREPL,FAM169A,KIAA0040,KLHL3,SACS,RB1,PACRGL,DRAM1,CLIP1,PCDH17,PPARGC1A,NCSTN,KLF12,KIT" MicroRNA hsa-miR-199b-5p:TargetScan hsa-miR-199b-5p TargetScan 5.48E-09 2.92E-05 1.66E-08 1.52E-07 22 422 "RALGAPA1,MCFD2,ATP1A2,PNP,PDE4D,GPR180,LYSMD3,CLOCK,PREPL,FAM169A,KIAA0040,KLHL3,SACS,RB1,PACRGL,DRAM1,CLIP1,PCDH17,PPARGC1A,NCSTN,KLF12,KIT" MicroRNA hsa-miR-3155:mirSVR_highEffct hsa-miR-3155:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.62E-09 2.99E-05 1.70E-08 1.55E-07 28 666 "HOMEZ,CAST,CCDC122,CFAP54,SNCAIP,FAM169A,FCRL5,FCRL2,DMXL1,TINF2,RABGAP1L,PARPBP,NR1I3,RNF4,ABCA11P,TOMM40L,N4BP2L2,TNFRSF19,POLK,ZNF667,LPIN1,STRN,CRB1,TGFBI,ATP6V0A2,NPL,TPO,AXDND1" MicroRNA hsa-miR-15b:PITA hsa-miR-15b:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-497:PITA hsa-miR-497:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-195:PITA hsa-miR-195:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-424:PITA hsa-miR-424:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-15a:PITA hsa-miR-15a:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-16:PITA hsa-miR-16:PITA_TOP PITA 5.66E-09 3.01E-05 1.70E-08 1.56E-07 30 754 "ABL2,NYNRIN,ARHGAP5,SLC4A4,PPP1R12B,BCL2L2,CACNA1E,PCDH9,DCLK1,CDK17,CFAP45,CLOCK,NCOR2,LRRTM2,TMEM161B,LATS2,MBNL2,TBC1D19,SLC22A17,SUCO,FOXO1,IVNS1ABP,SLC12A2,MYT1L,PCDH17,COP1,GPN1,NSD2,ZMYM2,CHPT1" MicroRNA hsa-miR-1285:mirSVR_highEffct hsa-miR-1285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.68E-09 3.02E-05 1.71E-08 1.56E-07 33 891 "MYBPC1,STARD13,NEDD8,CBLN3,SLC5A8,ZNF595,NRXN1,FAM163A,CSNK1G3,SNX17,SPATA18,NUDT12,PPP2R3C,RGS4,PACRGL,BORA,TNFRSF19,PIBF1,FLT1,GOLGA2P5,NR5A2,CYP1B1-AS1,PDS5B,ZNF274,ATP8A2,MCCC2,GJB2,FCRLA,ZNF26,IL6ST,CHPT1,LMNB1,CDK2AP1" MicroRNA hsa-miR-6779-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-09 3.09E-05 1.74E-08 1.60E-07 28 667 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-30b-3p:Functional MTI Functional MTI miRTarbase 5.80E-09 3.09E-05 1.74E-08 1.60E-07 28 667 "MATN3,HOMEZ,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,FNIP1,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-4278:mirSVR_highEffct hsa-miR-4278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.82E-09 3.09E-05 1.75E-08 1.60E-07 19 315 "WDR35,SLC5A8,DCLK1,STRN3,DCAF8,SREK1,RABGGTA,EFNA5,EFS,ARSK,FBXO11,INSM2,TMED2,TGFBI,RAB2B,HSP90B1,UBE2K,KCNT2,LCP1" MicroRNA hsa-miR-6747-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-09 3.10E-05 1.75E-08 1.60E-07 24 501 "ABL2,ADD1,SLC4A4,RILPL1,PIWIL1,SMIM14,THAP6,CEP135,RABGAP1L,DNMT3A,ZNF329,EFNA5,DCUN1D2,FCAR,VEZT,DDX51,BRMS1L,ZNF667,UGGT2,SPIC,RASSF6,GPN1,TXK,FAM151B" MicroRNA hsa-miR-23a-3p:Functional MTI Functional MTI miRTarbase 5.86E-09 3.12E-05 1.76E-08 1.61E-07 17 249 "MAP1B,RGS5,MCFD2,APAF1,EGLN3,GRTP1,TLR6,FNIP1,KDM3B,ERBIN,PPARGC1A,ADAM17,KLF12,ZNF550,DCP2,IRF1,LMNB1" MicroRNA hsa-miR-223-3p:TargetScan hsa-miR-223-3p TargetScan 6.06E-09 3.22E-05 1.81E-08 1.66E-07 18 282 "MAP1B,APC,NCOA1,SCARB1,CDK17,PDE4D,POU2F1,LACC1,RASA1,RNF4,DLEU1,FOXO1,BRMS1L,PDS5B,NFASC,KLF12,HSP90B1,IL6ST" MicroRNA hsa-miR-515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.06E-09 3.22E-05 1.81E-08 1.66E-07 15 189 "POLE,POU2F1,HEATR5A,PRKD1,FAM129A,MPHOSPH9,PCBD2,FCGR3B,POTEM,KDM5B,KDM3B,ZNF544,ADAM17,TGFBI,C12orf73" MicroRNA hsa-miR-556-3p:PITA hsa-miR-556-3p:PITA_TOP PITA 6.51E-09 3.46E-05 1.95E-08 1.78E-07 15 190 "SLC4A4,PDGFRA,RCBTB2,GPR180,ZFYVE16,MATR3,G3BP2,TMEM161B,MBNL2,FOXO1,SLC12A2,PPARGC1A,ADGRL3,EML4,IGF1" MicroRNA hsa-miR-4254:mirSVR_highEffct hsa-miR-4254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-09 3.52E-05 1.98E-08 1.81E-07 26 586 "RALGAPA1,NCOA1,SLC4A4,CADM3,CD84,PAH,SNTG2,PCDH9,SCFD2,HOMER1,SNCAIP,OCIAD1,NR1H4,GUSBP3,EIF2D,SNORA49,FCAMR,FAM81B,FCAR,SLC34A2,NUBPL,KDM3B,GZMH,TPO,KIT,RMST" MicroRNA hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 6.65E-09 3.54E-05 1.98E-08 1.82E-07 23 465 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,SDC1,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK,SLAIN1" MicroRNA "TGAATGT,MIR-181A:MSigDB" "TGAATGT,MIR-181A:MSigDB" MSigDB 6.65E-09 3.54E-05 1.98E-08 1.82E-07 23 465 "MAP1B,BIRC6,MYBPC1,PPP1R12B,ARHGEF7,NOVA1,ZNF664,PDGFRA,SLC25A3,NRXN1,AKAP6,CSNK1G3,TBC1D4,G3BP2,RAN,MBNL2,ETF1,FBXO11,IVNS1ABP,TBC1D1,PPIP5K2,TGFBI,ZBTB41" MicroRNA "TGAATGT,MIR-181C:MSigDB" "TGAATGT,MIR-181C:MSigDB" MSigDB 6.65E-09 3.54E-05 1.98E-08 1.82E-07 23 465 "MAP1B,BIRC6,MYBPC1,PPP1R12B,ARHGEF7,NOVA1,ZNF664,PDGFRA,SLC25A3,NRXN1,AKAP6,CSNK1G3,TBC1D4,G3BP2,RAN,MBNL2,ETF1,FBXO11,IVNS1ABP,TBC1D1,PPIP5K2,TGFBI,ZBTB41" MicroRNA "TGAATGT,MIR-181B:MSigDB" "TGAATGT,MIR-181B:MSigDB" MSigDB 6.65E-09 3.54E-05 1.98E-08 1.82E-07 23 465 "MAP1B,BIRC6,MYBPC1,PPP1R12B,ARHGEF7,NOVA1,ZNF664,PDGFRA,SLC25A3,NRXN1,AKAP6,CSNK1G3,TBC1D4,G3BP2,RAN,MBNL2,ETF1,FBXO11,IVNS1ABP,TBC1D1,PPIP5K2,TGFBI,ZBTB41" MicroRNA "TGAATGT,MIR-181D:MSigDB" "TGAATGT,MIR-181D:MSigDB" MSigDB 6.65E-09 3.54E-05 1.98E-08 1.82E-07 23 465 "MAP1B,BIRC6,MYBPC1,PPP1R12B,ARHGEF7,NOVA1,ZNF664,PDGFRA,SLC25A3,NRXN1,AKAP6,CSNK1G3,TBC1D4,G3BP2,RAN,MBNL2,ETF1,FBXO11,IVNS1ABP,TBC1D1,PPIP5K2,TGFBI,ZBTB41" MicroRNA hsa-miR-572:mirSVR_lowEffct hsa-miR-572:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.72E-09 3.58E-05 2.00E-08 1.84E-07 20 353 "PITPNM2,CARMIL3,BCL2L2,NGDN,PIGG,RAN,STX2,F10,GORAB,N4BP2L2,SUCO,MYO16,DRC1,LPIN1,INSM2,MTUS2,KMT5A,NSD2,FIP1L1,AXDND1" MicroRNA hsa-miR-1284:PITA hsa-miR-1284:PITA_TOP PITA 6.78E-09 3.61E-05 2.02E-08 1.85E-07 22 427 "MAP1B,CARMIL3,NRXN1,ATAD2B,BOD1L1,HOMER1,DNM3,SPATA18,CEP120,RASA1,ETF1,FNIP1,FOXO1,TADA1,PDS5B,NFASC,ERBIN,PCDH17,ANO4,KLF12,IGF1,SPTSSA" MicroRNA "GTGCCTT,MIR-506:MSigDB" "GTGCCTT,MIR-506:MSigDB" MSigDB 6.81E-09 3.62E-05 2.03E-08 1.86E-07 28 672 "SEMA6A,ATP2B4,RILPL1,FCHO2,PCDH9,FAM177A1,AKAP6,CLOCK,GALNT9,ITSN2,PRKD1,SREK1,ELK3,ZNF219,SUCO,ALKAL2,ARHGEF40,SLC12A2,SLC15A4,SLC22A5,LIMCH1,KIF21B,IQGAP2,TBC1D1,XPO4,TDG,GRSF1,IRF1" MicroRNA hsa-miR-5010-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-09 3.74E-05 2.10E-08 1.92E-07 14 163 "FBRSL1,PNP,ITGBL1,HOMER1,CLOCK,CSNK1G3,CEP135,DMXL1,CLIP4,KLHL12,CLIP1,TFDP1,AP4S1,TECRL" MicroRNA hsa-miR-18b*:mirSVR_highEffct hsa-miR-18b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.05E-09 3.75E-05 2.10E-08 1.92E-07 20 354 "SLC4A4,NOVA1,MPZL1,FCHO2,CD1E,ZNF595,RCHY1,PM20D1,NR1I3,ATG10,FAM228A,MEMO1,FLT3,SLC12A2,NFASC,LILRB1,BRD8,KLF12,LHX9,KIR2DL1" MicroRNA hsa-miR-302c-3p:Functional MTI Functional MTI miRTarbase 7.32E-09 3.89E-05 2.18E-08 1.99E-07 24 507 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,RNF4,SBNO1,ELOVL7,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK,IL6ST" MicroRNA "ATTCTTT,MIR-186:MSigDB" "ATTCTTT,MIR-186:MSigDB" MSigDB 7.44E-09 3.95E-05 2.21E-08 2.02E-07 17 253 "RGS5,MCFD2,BTF3,CAST,SLC25A3,DNM3,G3BP2,ARGLU1,EIF2D,MBNL2,RASA3,NR5A2,MYT1L,PDS5B,TMED2,COP1,ZBTB41" MicroRNA "CTTGTAT,MIR-381:MSigDB" "CTTGTAT,MIR-381:MSigDB" MSigDB 7.50E-09 3.99E-05 2.23E-08 2.04E-07 15 192 "BIRC6,CARMIL3,NFKBIA,FCHO2,NRXN1,ARGLU1,MBNL2,MPHOSPH9,ETF1,ELOVL7,NBEA,NR5A2,PDS5B,ANO4,KLF12" MicroRNA hsa-miR-3162:mirSVR_highEffct hsa-miR-3162:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-09 4.00E-05 2.23E-08 2.04E-07 27 632 "RALGAPA1,NDRG2,SLAMF6,COG6,B4GALT3,PCSK1,TOGARAM2,DCAF8,SLC9C2,CWC27,DLEU1,N4BP2L2,FTLP10,TM9SF1,KDM5B,NAAA,KLHL20,NCSTN,RAB2B,FZD10,KCNT2,ZNF470,C12orf73,PLB1,CCDC190,LHX9,IFT88" MicroRNA hsa-miR-511:PITA hsa-miR-511:PITA_TOP PITA 7.60E-09 4.04E-05 2.25E-08 2.06E-07 24 508 "SEMA6A,LDB2,NRXN1,CSNK1G3,ITSN2,DCAF8,CEP350,LATS2,MBNL2,DCUN1D2,STK32B,SLC22A17,FGF9,PLEKHA6,ERBIN,PPARGC1A,METAP2,EML4,DOCK9,EMILIN1,TFDP1,FZD10,HMGCR,TENT2" MicroRNA hsa-miR-4789-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.88E-09 4.19E-05 2.34E-08 2.14E-07 17 254 "MYBPC1,PGGT1B,ITGBL1,NUP37,BRI3BP,CEP135,LATS2,ZNF256,BRMS1L,SLC12A2,LILRB1,MSH6,RASSF6,TECRL,NLRP8,IL6ST,ZMYM2" MicroRNA hsa-miR-342-5p:mirSVR_lowEffct hsa-miR-342-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.90E-09 4.20E-05 2.34E-08 2.14E-07 36 1047 "KIAA1211,SLAMF6,PITPNM2,PPFIA4,FAM193A,CENPBD1P1,FGFRL1,ARHGEF7,CAST,CENPC,WDFY2,TSTD1,PTPRVP,TAPT1,POLE,FAM169A,EIF2AK2,COG3,DNMT3A,CLIP4,RNF4,GP6,STK32B,F7,LRRN2,STAB2,P2RX2,KIF21B,NMNAT2,ERAP1,TCF7,FCRLA,TPO,LHX9,KIT,MFSD2B" MicroRNA hsa-miR-494-3p:Functional MTI Functional MTI miRTarbase 7.93E-09 4.22E-05 2.35E-08 2.15E-07 13 138 "MCC,MDM4,ARHGAP5,UHMK1,RB1,REST,LATS2,ETF1,SDC1,SLC8A1,GALP,PABPN1,SPATA13" MicroRNA hsa-miR-188-5p:PITA hsa-miR-188-5p:PITA_TOP PITA 8.05E-09 4.28E-05 2.38E-08 2.18E-07 15 193 "ODC1,PCDH9,MTX3,RASA1,LATS2,FNIP1,FBXO11,NBEA,SLC12A2,MYT1L,ERBIN,KLHL20,KLF12,NSD2,ZNF470" MicroRNA hsa-miR-99a*:mirSVR_lowEffct hsa-miR-99a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.29E-09 4.41E-05 2.45E-08 2.25E-07 25 551 "COG6,HOMEZ,ATP2B4,RAB29,NOVA1,CD1D,SMIM14,JAKMIP1,FAM163A,CEP135,PRKD1,SNX17,NUDT12,ATG10,ELOVL7,PIBF1,HSPH1,GC,MIMT1,DOCK9,TDG,ADAMTS19,JCHAIN,KIT,LOX" MicroRNA hsa-miR-6799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-09 4.52E-05 2.51E-08 2.30E-07 28 679 "MATN3,PPP1R12B,PDGFRA,PIGR,EPN1,NCOR2,BRI3BP,UBXN2A,NOS1AP,SUPT7L,SLC35F6,ZNF329,DTD2,MARVELD2,TCTN2,TBC1D19,ARSK,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-1229:mirSVR_highEffct hsa-miR-1229:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.85E-09 4.71E-05 2.62E-08 2.40E-07 27 637 "WDR35,APC,ASCL1,MPZL1,PDGFRA,ITGBL1,ZNF586,DCAF8,FBXL5,FAM228A,NLRP2,ARHGEF40,SLC12A2,SLC22A5,ZNF667,COMMD6,ZNF544,TMED2,GPR12,CRB1,SLC7A8,HEXB,ADAMTS19,UGT2B7,ZNF876P,LHX9,ZBED3-AS1" MicroRNA hsa-miR-377-3p:TargetScan hsa-miR-377-3p TargetScan 9.12E-09 4.85E-05 2.69E-08 2.47E-07 23 473 "CUL4A,NCOA1,KCTD12,PNP,PDE4D,PDGFRA,AKAP6,HEATR5A,CEP135,PRKD1,RABGAP1L,RASA1,DRAM1,NBEA,ATP8A2,NPAS3,PPARGC1A,GRSF1,DCP2,IGF1,LHX9,FAM49A,KIF2A" MicroRNA hsa-miR-580:PITA hsa-miR-580:PITA_TOP PITA 9.18E-09 4.88E-05 2.71E-08 2.48E-07 19 324 "MAP1B,FCHO2,PCSK1,ATAD2B,CLOCK,CSNK1G3,DNM3,SREK1,PARPBP,TMEM161B,MEMO1,ETF1,FGF9,NBEA,IVNS1ABP,ANO4,BAZ1A,KLF12,HTR2A" MicroRNA hsa-miR-605:PITA hsa-miR-605:PITA_TOP PITA 9.35E-09 4.97E-05 2.76E-08 2.53E-07 18 290 "MAP1B,NLN,ODC1,CFL2,BOD1L1,CLOCK,CSNK1G3,LRRTM2,MTX3,MBNL2,SLC30A6,MYT1L,KDM5B,KDM3B,PCDH17,ADGRL3,NSD2,ZNF470" MicroRNA hsa-miR-509-3p:mirSVR_highEffct hsa-miR-509-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.64E-09 5.13E-05 2.84E-08 2.60E-07 26 597 "MCFD2,BLZF1,PCDH9,PCK2,CDK17,RCHY1,CSNK1G3,LRRTM2,FCRL5,ZFYVE16,COCH,RABGAP1L,PARPBP,NR1I3,NR1H4,CWC27,ABCA11P,CLIP1,FCAR,TMEM183A,OXGR1,ATP11A,BAZ1A,RIMBP2,GUF1,ZMYM2" MicroRNA hsa-miR-611:mirSVR_lowEffct hsa-miR-611:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-08 5.47E-05 3.03E-08 2.77E-07 22 437 "RALGAPA1,TBC1D14,NLRP4,ZNF664,GLT1D1,CHD1,AKAP6,SPATA18,PIGG,RB1,PACRGL,EFNA5,CWC27,TMEM175,SLC30A6,MEGF10,LPIN1,ANO4,KMT5A,PAPPA2,ANKS1B,LINC00442" MicroRNA hsa-miR-22:mirSVR_highEffct hsa-miR-22:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.04E-08 5.54E-05 3.07E-08 2.81E-07 27 642 "ABL2,CCDC181,NOVA1,CD1D,CDK17,VIT,PGGT1B,TSTD1,HOMER1,VCAN,DNM3,RAN,CRYL1,PACRGL,DNAJC27,USP44,TOMM40L,PIBF1,FLT3,GOLGA2P5,UFM1,ZNF605,NPAS3,LRCH1,TGFBI,MAEL,RXFP2" MicroRNA hsa-miR-362-3p:TargetScan hsa-miR-362-3p TargetScan 1.05E-08 5.60E-05 3.10E-08 2.84E-07 17 259 "PPFIA4,NCOA1,PDE4D,PFKFB2,POU2F1,CSNK1G3,MATR3,DNMT3A,PCGF3,ATP11A,ADAM17,KHNYN,KLF12,IL6ST,LHX9,KIF2A,PABPN1" MicroRNA hsa-miR-329-3p:TargetScan hsa-miR-329-3p TargetScan 1.05E-08 5.60E-05 3.10E-08 2.84E-07 17 259 "PPFIA4,NCOA1,PDE4D,PFKFB2,POU2F1,CSNK1G3,MATR3,DNMT3A,PCGF3,ATP11A,ADAM17,KHNYN,KLF12,IL6ST,LHX9,KIF2A,PABPN1" MicroRNA hsa-miR-216a:PITA hsa-miR-216a:PITA_TOP PITA 1.07E-08 5.71E-05 3.16E-08 2.89E-07 20 363 "MCC,NCOA1,PCCA,BOD1L1,MATR3,KLHL3,F11R,RB1,TMEM161B,MBNL2,ETF1,FNIP1,NR5A2,KIF21B,KDM3B,PCDH17,PPARGC1A,ADGRL3,EML4,KLF12" MicroRNA hsa-miR-365:mirSVR_highEffct hsa-miR-365:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.14E-08 6.06E-05 3.35E-08 3.07E-07 25 560 "EP400,SNX24,PCK2,THAP6,LYSMD3,VCAN,G3BP2,SAP18,ABCA11P,GORAB,RUBCNL,PKD2L2,CGREF1,CYP1B1-AS1,MEGF10,GABRA2,UHRF1BP1L,SRP72,LPIN1,METAP2,TEP1,TFDP1,ZNF721,ADAMTS19,STARD4" MicroRNA hsa-miR-219-5p:mirSVR_highEffct hsa-miR-219-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.15E-08 6.13E-05 3.38E-08 3.10E-07 23 479 "NCOA1,CACNA1E,PDGFRA,PIGR,AKAP6,TOGARAM2,MPHOSPH9,ELOVL7,RELL1,FLT1,NR5A2,UGGT2,CMPK2,MCCC2,PPARGC1A,GJA3,PPIP5K2,METAP2,ADGRL3,ACSL6,ADAMTS19,DIAPH3,LTA4H" MicroRNA hsa-miR-1226:mirSVR_highEffct hsa-miR-1226:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-08 6.27E-05 3.46E-08 3.17E-07 26 603 "SFTA3,CDKL2,CAST,UHMK1,SNTG2,NCR1,DCAF8,RASA1,GUSBP3,KLHL12,DHRS2,NDUFAF7,FBXO11,NUBPL,UFM1,SLC8A1,CGREF1,EFR3B,NPAS3,CMPK2,SRP72,EML4,ADAMTS19,ZNF876P,ZMYM2,LTA4H" MicroRNA "TGGTGCT,MIR-29C:MSigDB" "TGGTGCT,MIR-29C:MSigDB" MSigDB 1.20E-08 6.37E-05 3.51E-08 3.21E-07 23 480 "BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,STRN3,NCOR2,DNM3,DNMT3A,KIRREL1,PCGF3,CHFR,NFASC,PPARGC1A,PSME4,EML4,KMT5C,TDG,KLF12,HMGCR,NSD2,IGF1,ZBTB41" MicroRNA "TGGTGCT,MIR-29B:MSigDB" "TGGTGCT,MIR-29B:MSigDB" MSigDB 1.20E-08 6.37E-05 3.51E-08 3.21E-07 23 480 "BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,STRN3,NCOR2,DNM3,DNMT3A,KIRREL1,PCGF3,CHFR,NFASC,PPARGC1A,PSME4,EML4,KMT5C,TDG,KLF12,HMGCR,NSD2,IGF1,ZBTB41" MicroRNA "TGGTGCT,MIR-29A:MSigDB" "TGGTGCT,MIR-29A:MSigDB" MSigDB 1.20E-08 6.37E-05 3.51E-08 3.21E-07 23 480 "BIRC6,PITPNM2,SNX24,ATP2B4,NFATC4,STRN3,NCOR2,DNM3,DNMT3A,KIRREL1,PCGF3,CHFR,NFASC,PPARGC1A,PSME4,EML4,KMT5C,TDG,KLF12,HMGCR,NSD2,IGF1,ZBTB41" MicroRNA hsa-miR-1976:mirSVR_highEffct hsa-miR-1976:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-08 6.48E-05 3.57E-08 3.27E-07 26 604 "MDM4,ARL1,FAM193A,SLC5A6,TSSK4,PDE4D,VIT,WDFY2,SMIM14,PKP1,THAP6,AKAP6,POU2F1,CSNK1G3,RNF31,RASA1,LGR6,SLC22A17,TMEM156,POLK,NAAA,ZBTB37,ADAMTS19,SPTSSA,FIP1L1,AXDND1" MicroRNA hsa-let-7g-5p:TargetScan hsa-let-7g-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7f-5p:TargetScan hsa-let-7f-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7a-5p:TargetScan hsa-let-7a-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7c-5p:TargetScan hsa-let-7c-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7e-5p:TargetScan hsa-let-7e-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-miR-98-5p:TargetScan hsa-miR-98-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7b-5p:TargetScan hsa-let-7b-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7i-5p:TargetScan hsa-let-7i-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-let-7d-5p:TargetScan hsa-let-7d-5p TargetScan 1.23E-08 6.53E-05 3.58E-08 3.28E-07 32 873 "ABL2,MDM4,NLN,NYNRIN,NCOA1,ATP2B4,PPP1R12B,ARHGEF7,NOVA1,CACNA1E,CFL2,ATAD2B,AKAP6,GNPTAB,POU2F1,CLOCK,CEP135,DCAF8,RB1,SBNO1,DCUN1D2,PCGF3,FNIP1,POTEM,GABRB1,KIF21B,PPARGC1A,ACSL6,KHNYN,IGF1,LMLN,KIF2A" MicroRNA hsa-miR-320a:PITA hsa-miR-320a:PITA_TOP PITA 1.24E-08 6.62E-05 3.62E-08 3.31E-07 23 481 "SFTA3,MAP1B,SEMA6A,WDR19,ARHGAP5,LDB2,ATAD2B,BOD1L1,SREK1,RASA1,EIF2D,EFS,PCGF3,USP44,FOXO1,ZCCHC8,FBXO11,MYT1L,PPARGC1A,ATP11A,TDG,BAZ1A,SPTSSA" MicroRNA hsa-miR-1825:mirSVR_highEffct hsa-miR-1825:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-08 6.62E-05 3.62E-08 3.31E-07 23 481 "ZNF784,ATP1A2,ATP2B4,UHMK1,PCCA,CFL2,EPGN,NUDT12,TXNDC15,ARSK,NDUFAF7,PIBF1,PKD2L2,CYP1B1-AS1,PDS5B,CENPJ,ERBIN,PCDH17,TGM1,TECRL,ZBED3-AS1,CHPT1,KIT" MicroRNA hsa-miR-320d:PITA hsa-miR-320d:PITA_TOP PITA 1.24E-08 6.62E-05 3.62E-08 3.31E-07 23 481 "SFTA3,MAP1B,SEMA6A,WDR19,ARHGAP5,LDB2,ATAD2B,BOD1L1,SREK1,RASA1,EIF2D,EFS,PCGF3,USP44,FOXO1,ZCCHC8,FBXO11,MYT1L,PPARGC1A,ATP11A,TDG,BAZ1A,SPTSSA" MicroRNA hsa-miR-320c:PITA hsa-miR-320c:PITA_TOP PITA 1.24E-08 6.62E-05 3.62E-08 3.31E-07 23 481 "SFTA3,MAP1B,SEMA6A,WDR19,ARHGAP5,LDB2,ATAD2B,BOD1L1,SREK1,RASA1,EIF2D,EFS,PCGF3,USP44,FOXO1,ZCCHC8,FBXO11,MYT1L,PPARGC1A,ATP11A,TDG,BAZ1A,SPTSSA" MicroRNA hsa-miR-320b:PITA hsa-miR-320b:PITA_TOP PITA 1.24E-08 6.62E-05 3.62E-08 3.31E-07 23 481 "SFTA3,MAP1B,SEMA6A,WDR19,ARHGAP5,LDB2,ATAD2B,BOD1L1,SREK1,RASA1,EIF2D,EFS,PCGF3,USP44,FOXO1,ZCCHC8,FBXO11,MYT1L,PPARGC1A,ATP11A,TDG,BAZ1A,SPTSSA" MicroRNA hsa-miR-520g-3p:Functional MTI Functional MTI miRTarbase 1.28E-08 6.79E-05 3.71E-08 3.39E-07 21 404 "MCFD2,BCL2L2,CDKL2,CFL2,PIK3C2B,PKP1,C12orf65,DCAF8,OCIAD1,RABGAP1L,SLC35F6,C14orf119,N4BP2L2,FOXO1,G2E3,ZNF446,OXGR1,GTF2H3,TMPO,TXK,NSD2" MicroRNA hsa-miR-380*:mirSVR_highEffct hsa-miR-380*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-08 6.86E-05 3.74E-08 3.43E-07 20 367 "KIAA1211,SNX24,ARL1,NOP14,ASCL1,ASTN1,PCK2,CSNK1G3,DNMT3A,RASA1,PACRGL,MAEA,RELL1,POLK,GABRA2,KIF21B,EAPP,NPAS3,HEXB,FIP1L1" MicroRNA hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 1.35E-08 7.19E-05 3.92E-08 3.59E-07 18 297 "SCARB1,SLC25A3,POLE,LACC1,BIVM,PSME1,RAN,MEMO1,SAP18,TMEM129,TACC3,FOXO1,POTEM,ACIN1,METAP2,MSH6,HSD17B4,NSD2" MicroRNA hsa-miR-1908:mirSVR_lowEffct hsa-miR-1908:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-08 7.20E-05 3.93E-08 3.60E-07 31 830 "ADORA1,RGS5,FGFRL1,ARHGEF7,SLC5A6,CACNA1E,PDGFRA,PITX1,NOC4L,THTPA,KIAA0040,WDR1,C14orf119,GUSBP3,MARVELD2,ZNF219,SAP18,MAEA,CLIP1,TACC3,FLT1,SLC34A2,KIF21B,NAAA,EMILIN1,SLC7A8,ZFHX2,KIF3C,KIR2DS4,NUAK2,AXDND1" MicroRNA hsa-miR-1233:mirSVR_highEffct hsa-miR-1233:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-08 7.22E-05 3.94E-08 3.60E-07 19 332 "BIRC6,NLN,ARL1,NCOA1,SLC4A4,LDB2,ITGBL1,EGLN3,RGS12,POLK,VEZT,CYP1B1-AS1,TMEM183A,MRPS27,TDG,CRB1,GTF3C2,TTC41P,PABPN1" MicroRNA hsa-miR-942-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.39E-08 7.41E-05 4.03E-08 3.69E-07 15 201 "MDM4,ADD1,ASCL1,PPP1R3E,NFKBIA,POU2F1,PRKD1,G3BP2,ATP6AP1L,FCGR3B,FGF9,FOXO1,POTEM,PCDH17,ACSL6" MicroRNA hsa-miR-216b-5p:TargetScan hsa-miR-216b-5p TargetScan 1.40E-08 7.43E-05 4.05E-08 3.70E-07 17 264 "ABL2,MDM4,CUL4A,CAD,DCLK1,CFL2,CHD1,C1orf116,POLR1D,PCBD2,GABRB1,PPIP5K2,MSH6,ATP6V0A2,KLF12,DCP2,FAM151B" MicroRNA hsa-miR-520h:Functional MTI Functional MTI miRTarbase 1.45E-08 7.71E-05 4.19E-08 3.84E-07 21 407 "MCFD2,BCL2L2,CDKL2,CFL2,PIK3C2B,PKP1,C12orf65,DCAF8,OCIAD1,RABGAP1L,SLC35F6,C14orf119,N4BP2L2,FOXO1,G2E3,ZNF446,OXGR1,GTF2H3,TMPO,TXK,NSD2" MicroRNA "ACTGTGA,MIR-27A:MSigDB" "ACTGTGA,MIR-27A:MSigDB" MSigDB 1.54E-08 8.19E-05 4.45E-08 4.07E-07 22 447 "MATN3,SEMA6A,PITPNM2,APAF1,NCOA1,B4GALT3,NOVA1,CDK18,PDGFRA,NRXN1,ITSN2,SREK1,ARGLU1,MBNL2,DNAJC27,SUCO,FOXO1,NR5A2,PDS5B,NFASC,PCDH17,DCP2" MicroRNA "ACTGTGA,MIR-27B:MSigDB" "ACTGTGA,MIR-27B:MSigDB" MSigDB 1.54E-08 8.19E-05 4.45E-08 4.07E-07 22 447 "MATN3,SEMA6A,PITPNM2,APAF1,NCOA1,B4GALT3,NOVA1,CDK18,PDGFRA,NRXN1,ITSN2,SREK1,ARGLU1,MBNL2,DNAJC27,SUCO,FOXO1,NR5A2,PDS5B,NFASC,PCDH17,DCP2" MicroRNA hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA_TOP PITA 1.56E-08 8.31E-05 4.51E-08 4.13E-07 23 487 "APC,NCOA1,ATP2B4,CADM3,CAMK4,FCHO2,ATAD2B,HOMER1,LYSMD3,DDX59,MATR3,DNMT3A,TXNDC15,ETF1,FNIP1,CCDC88A,MYT1L,PCDH17,ADGRL3,SLAIN1,IGF1,ZNF470,ANKS1B" MicroRNA hsa-miR-107:Functional MTI Functional MTI miRTarbase 1.58E-08 8.39E-05 4.56E-08 4.17E-07 18 300 "ABL2,MDM4,SEMA6A,MYBPC1,FGFRL1,CLOCK,CSNK1G3,VCAN,SREK1,G3BP2,ARGLU1,LATS2,CLIP1,FOXO1,TM9SF1,GABRB1,EML4,FAM49A" MicroRNA hsa-miR-194*:mirSVR_highEffct hsa-miR-194*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.59E-08 8.44E-05 4.58E-08 4.19E-07 26 612 "SFTA3,PITPNM2,FAM193A,AACS,NOVA1,CAST,LDB2,PDGFRA,TAPT1,GNPTAB,PREPL,SNCAIP,ZNF586,OCIAD1,G3BP2,ARGLU1,SMC6,MBNL2,CCDC88A,SLC22A4,CIDEB,PSME4,TGFBI,ADAMTS19,ZNF550,ZBED3-AS1" MicroRNA hsa-miR-1827:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-08 8.71E-05 4.73E-08 4.33E-07 31 837 "MATN3,MDM4,HOMEZ,APAF1,NOP14,FGFRL1,PDGFRA,CFL2,PIGR,MPHOSPH8,SUPT7L,SLC35F6,DTD2,TMEM33,TCTN2,TBC1D19,FAM172A,ARSK,UTP15,SH3BP2,SLC30A6,MRPS14,DCAF11,SNRNP35,COX18,GRSF1,ATP6V0A2,HSP90B1,GUF1,PGAM5,LETM1" MicroRNA hsa-miR-631:mirSVR_highEffct hsa-miR-631:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-08 8.75E-05 4.74E-08 4.34E-07 21 410 "MCC,ATP4B,THAP6,SNCAIP,VCAN,TINF2,PARPBP,DTD2,PCGF3,FCGR2B,SLC12A2,WDCP,SLC22A5,YPEL5,TMEM183A,ZNF274,IGSF8,GUF1,GALP,CHPT1,TTC41P" MicroRNA hsa-miR-6833-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-08 9.62E-05 5.20E-08 4.76E-07 19 338 "NLN,COG6,ASCL1,MYBPC1,PPP1R3E,UHMK1,SMIM14,NUP37,POU2F1,ATP6AP1L,FGF9,N4BP2,ZNF667,CENPJ,PCDH17,MSH6,TMEM174,GALP,FAM151B" MicroRNA hsa-miR-216b:PITA hsa-miR-216b:PITA_TOP PITA 1.81E-08 9.62E-05 5.20E-08 4.76E-07 19 338 "RALGAPA1,SFTA3,CUL4A,CFL2,ATAD2B,MATR3,BIVM,CEP350,MBNL2,TNFRSF19,SUCO,ALKAL2,GABRB1,ERBIN,PPIP5K2,EML4,KMT5A,KLF12,KCNT2" MicroRNA hsa-miR-4768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-08 9.62E-05 5.20E-08 4.76E-07 19 338 "NLN,COG6,ASCL1,MYBPC1,PPP1R3E,UHMK1,SMIM14,NUP37,POU2F1,ATP6AP1L,FGF9,N4BP2,ZNF667,CENPJ,PCDH17,MSH6,TMEM174,GALP,FAM151B" MicroRNA hsa-miR-589:mirSVR_highEffct hsa-miR-589:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-08 9.62E-05 5.20E-08 4.76E-07 26 616 "NDRG2,B4GALT3,ADGRF3,HECTD1,ZFYVE16,FBXL5,RNASEL,DCUN1D2,ETF1,VEZT,NBEA,SLC30A6,THADA,RAPGEF6,ANKLE2,PCDH17,RNF212,NT5C1B,RIMBP2,TNR,TXK,TTC41P,RMST,NUAK2,AXDND1,LMNB1" MicroRNA hsa-miR-1266:mirSVR_highEffct hsa-miR-1266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-08 9.93E-05 5.37E-08 4.92E-07 26 617 "ASTN1,CENPBD1P1,UHMK1,PAH,PCK2,CEBPE,DCAF8,MATR3,TINF2,ATG10,KLHL12,UTP15,N4BP2L2,ARHGEF40,TADA1,TMEM183A,STRN,ADGRA3,ANO4,TCF7,COX18,NPL,UBE2K,ANKS1B,KIT,FAM71C" MicroRNA hsa-miR-520f:PITA hsa-miR-520f:PITA_TOP PITA 1.88E-08 9.98E-05 5.39E-08 4.93E-07 22 452 "MAP1B,ATP2B4,ARHGEF7,NOVA1,PCDH9,FAM177A1,CFL2,LYSMD3,CEP350,RNF219,CLIP4,NTN4,MBNL2,ETF1,DNAJC27,PKD2L2,KMT5C,BAZ1A,FZD10,IL6ST,ZBTB41,LMNB1" MicroRNA hsa-miR-3131:mirSVR_lowEffct hsa-miR-3131:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-08 1.00E-04 5.41E-08 4.95E-07 23 492 "RALGAPA1,TBC1D14,SLC4A4,NLRP4,CARMIL3,ZNF664,GLT1D1,CHD1,AKAP6,SPATA18,PIGG,RB1,PACRGL,EFNA5,CWC27,TMEM175,SLC30A6,MEGF10,ANO4,KMT5A,PAPPA2,ANKS1B,LOX" MicroRNA hsa-miR-122*:mirSVR_lowEffct hsa-miR-122*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-08 1.03E-04 5.58E-08 5.11E-07 21 414 "COG6,MCFD2,MSH2,AACS,DCLK1,CDK7,CHD1,SMIM14,C1orf116,STRN3,GNPTAB,COG3,DNMT3A,PACRGL,ETF1,GABRB1,NAAA,TBC1D1,WDR36,ZMYM2,FAM151B" MicroRNA hsa-miR-526a:PITA hsa-miR-526a:PITA_TOP PITA 2.00E-08 1.07E-04 5.74E-08 5.25E-07 12 123 "RALGAPA1,MAP1B,NCOA1,BCL2L2,AKAP6,EGLN3,FLT3,NMNAT2,JPH4,GRSF1,GTF3C2,KLF12" MicroRNA hsa-miR-519b-5p:PITA hsa-miR-519b-5p:PITA_TOP PITA 2.00E-08 1.07E-04 5.74E-08 5.25E-07 12 123 "RALGAPA1,MAP1B,NCOA1,BCL2L2,AKAP6,EGLN3,FLT3,NMNAT2,JPH4,GRSF1,GTF3C2,KLF12" MicroRNA hsa-miR-520c-5p:PITA hsa-miR-520c-5p:PITA_TOP PITA 2.00E-08 1.07E-04 5.74E-08 5.25E-07 12 123 "RALGAPA1,MAP1B,NCOA1,BCL2L2,AKAP6,EGLN3,FLT3,NMNAT2,JPH4,GRSF1,GTF3C2,KLF12" MicroRNA hsa-miR-519c-5p:PITA hsa-miR-519c-5p:PITA_TOP PITA 2.00E-08 1.07E-04 5.74E-08 5.25E-07 12 123 "RALGAPA1,MAP1B,NCOA1,BCL2L2,AKAP6,EGLN3,FLT3,NMNAT2,JPH4,GRSF1,GTF3C2,KLF12" MicroRNA hsa-miR-518d-5p:PITA hsa-miR-518d-5p:PITA_TOP PITA 2.00E-08 1.07E-04 5.74E-08 5.25E-07 12 123 "RALGAPA1,MAP1B,NCOA1,BCL2L2,AKAP6,EGLN3,FLT3,NMNAT2,JPH4,GRSF1,GTF3C2,KLF12" MicroRNA hsa-miR-574-5p:Functional MTI Functional MTI miRTarbase 2.03E-08 1.08E-04 5.79E-08 5.30E-07 21 415 "RGS5,FBRSL1,STXBP6,FGFRL1,PNP,CAMK4,FAM177A1,NRXN1,FAM163A,BRI3BP,LRRTM2,EIF2AK2,SLC35F6,RGS4,LATS2,PLEKHA6,NMNAT2,TNR,IGF1,ZFHX2,ZDHHC20" MicroRNA hsa-miR-194:PITA hsa-miR-194:PITA_TOP PITA 2.05E-08 1.09E-04 5.87E-08 5.38E-07 17 271 "BIRC6,PITPNM2,APC,ARHGAP5,PDE4D,CFL2,CHD1,LYSMD3,CEP350,DNMT3A,TMEM161B,MBNL2,BRMS1L,SLC8A1,TBC1D1,KMT5A,KLF12" MicroRNA hsa-miR-340-5p:Functional MTI Functional MTI miRTarbase 2.08E-08 1.11E-04 5.95E-08 5.45E-07 19 341 "WDR35,SNX24,CD84,FCHO2,UHMK1,PDE4D,LYSMD3,UBXN2A,BIVM,MTX3,DNMT3A,LRPPRC,MPHOSPH9,CWC27,CLIP1,ACIN1,PPIP5K2,TXK,ZNF324B" MicroRNA hsa-miR-3147:mirSVR_highEffct hsa-miR-3147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.11E-08 1.12E-04 6.02E-08 5.51E-07 23 495 "POU2F1,FCRL5,PTPRC,WDR1,RASA1,OGFOD2,RNF4,ZNF671,ARSK,MAEA,TMEM129,FCGR3B,RUBCNL,EAPP,ERAP1,KDM3B,PCDH17,BRD8,LINC02393,MAEL,NPL,PLB1,ZMYM2" MicroRNA hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 2.11E-08 1.12E-04 6.02E-08 5.51E-07 22 455 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK,LCP1" MicroRNA hsa-miR-1247:mirSVR_lowEffct hsa-miR-1247:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-08 1.14E-04 6.10E-08 5.58E-07 18 306 "NFATC4,BTF3,NGDN,ITSN2,RNF31,RB1,RGS12,LGR6,PCGF3,F10,STAB2,NAAA,TMEM183A,LILRB1,MAST4,ADGRL3,KMT5A,KIF3C" MicroRNA hsa-miR-581:PITA hsa-miR-581:PITA_TOP PITA 2.17E-08 1.16E-04 6.19E-08 5.67E-07 13 150 "RILPL1,PCDH9,AKAP6,HEATR5A,DNMT3A,FOXO1,SUPT20H,FBXO11,ALKAL2,PCDH17,STRN,STON1,ADAMTS19" MicroRNA hsa-miR-484:mirSVR_highEffct hsa-miR-484:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-08 1.16E-04 6.22E-08 5.70E-07 25 579 "CAST,CFAP54,SNCAIP,FAM169A,FCRL5,FCRL2,TINF2,RABGAP1L,PARPBP,NR1I3,ABCA11P,TOMM40L,N4BP2L2,POLK,ZNF667,DRC1,LPIN1,STRN,CRB1,ATP6V0A2,NPL,TPO,KIT,LINC01913,AXDND1" MicroRNA hsa-miR-1227:mirSVR_highEffct hsa-miR-1227:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.20E-08 1.17E-04 6.26E-08 5.73E-07 21 417 "COG6,CAMK4,PCK2,PCSK1,PDGFRA,CFAP54,ZFYVE16,CEP350,RNASEL,LATS2,KIRREL1,MARVELD2,ELOVL7,VEZT,RUBCNL,G2E3,PKD2L2,SULT1E1,DOCK9,HTR2A,ZNF470" MicroRNA hsa-miR-3152:mirSVR_highEffct hsa-miR-3152:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.22E-08 1.18E-04 6.31E-08 5.78E-07 27 666 "ARL1,ATP1A2,CAST,RGSL1,AKAP6,SYCP3,HEATR5A,LRRTM2,PACRGL,ABCA11P,GORAB,N4BP2L2,TNFRSF19,SUCO,CYP1B1-AS1,NAAA,OXGR1,KLHL20,METAP2,TDG,ZNF721,ZNF550,VRK2,LINC00272,LHX9,KCNN2,LINC01913" MicroRNA hsa-miR-4419b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-08 1.21E-04 6.45E-08 5.91E-07 23 497 "MATN3,HOMEZ,APAF1,CD1D,AKAP6,CLOCK,BRI3BP,UBXN2A,EIF2AK2,ZNF329,DTD2,MEMO1,MARVELD2,TBC1D19,ARSK,PCGF3,UTP15,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5" MicroRNA hsa-miR-4478:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-08 1.25E-04 6.68E-08 6.12E-07 23 498 "MATN3,HOMEZ,APAF1,CD1D,AKAP6,CLOCK,BRI3BP,UBXN2A,EIF2AK2,ZNF329,DTD2,MEMO1,MARVELD2,TBC1D19,ARSK,PCGF3,UTP15,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5" MicroRNA hsa-miR-3929:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-08 1.25E-04 6.68E-08 6.12E-07 23 498 "MATN3,HOMEZ,APAF1,CD1D,AKAP6,CLOCK,BRI3BP,UBXN2A,EIF2AK2,ZNF329,DTD2,MEMO1,MARVELD2,TBC1D19,ARSK,PCGF3,UTP15,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5" MicroRNA hsa-miR-1277:mirSVR_lowEffct hsa-miR-1277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-08 1.26E-04 6.73E-08 6.16E-07 22 458 "LRRC43,ARHGAP5,ATP2B4,ZNF595,AKAP6,DNM3,KIAA0040,F11R,C14orf119,B3GLCT,DLEU1,POLK,SUPT20H,PAICS,ATP8A2,TDG,CRB1,GPR161,ATP6V0A2,STARD4,SPRYD7,LMNB1" MicroRNA hsa-miR-224:PITA hsa-miR-224:PITA_TOP PITA 2.62E-08 1.40E-04 7.45E-08 6.82E-07 19 346 "MAP1B,TMEM132B,SLC4A4,KCTD12,CAST,PGGT1B,ATAD2B,DNM3,FBXL5,TMEM161B,MBNL2,SUCO,NR5A2,MYT1L,HMGCR,DCP2,ZBTB41,LHX9,ZDHHC20" MicroRNA hsa-miR-452-5p:TargetScan hsa-miR-452-5p TargetScan 2.72E-08 1.44E-04 7.70E-08 7.05E-07 16 243 "PPP1R12B,DCLK1,PDE4D,ANAPC4,MATR3,FBXO11,BRMS1L,PCDH17,PPIP5K2,GOLGA3,CNTN2,KLF12,IGF1,IL6ST,ANKS1B,KIT" MicroRNA hsa-miR-892c-3p:TargetScan hsa-miR-892c-3p TargetScan 2.72E-08 1.44E-04 7.70E-08 7.05E-07 16 243 "PPP1R12B,DCLK1,PDE4D,ANAPC4,MATR3,FBXO11,BRMS1L,PCDH17,PPIP5K2,GOLGA3,CNTN2,KLF12,IGF1,IL6ST,ANKS1B,KIT" MicroRNA hsa-miR-4290:mirSVR_highEffct hsa-miR-4290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-08 1.45E-04 7.73E-08 7.08E-07 20 384 "MDM4,NLN,ATP1A2,PNP,PCK2,THTPA,ZNF586,NOP9,ZNF329,CWC27,ADGRV1,PIBF1,YPEL5,MEGF10,GABRB1,AP4S1,TECRL,TMEM174,DCP2,CAB39L" MicroRNA hsa-miR-411-5p.2:TargetScan hsa-miR-411-5p.2 TargetScan 2.73E-08 1.45E-04 7.74E-08 7.09E-07 11 102 "MATN3,ARHGAP5,DCLK1,MPHOSPH8,MBNL2,FNIP1,FLT3,RAPGEF6,IQGAP2,MSH6,HSD17B4" MicroRNA hsa-miR-342-5p:mirSVR_highEffct hsa-miR-342-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-08 1.46E-04 7.78E-08 7.12E-07 19 347 "DHX37,AACS,NLRP4,COPA,GNPTAB,FCRL5,KLHL3,PTPRH,GALNT14,SUCO,PLEKHA6,GABRB1,TMEM183A,NFASC,LRCH1,PPARGC1A,ZNF26,FAM151B,LCP1" MicroRNA hsa-miR-550:mirSVR_highEffct hsa-miR-550:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.85E-08 1.51E-04 8.06E-08 7.38E-07 25 587 "ARHGAP5,ATP1A2,BCL2L2,BTF3,AP1G2,CACNA1E,AMDHD1,PCCA,PDGFRA,POU2F1,EPGN,SNCAIP,PSME1,FCAR,RELL1,ERBIN,SULT1E1,MTUS2,ADGRL3,ACSL6,TNR,NPL,IL6ST,KCNJ9,KCNN2" MicroRNA hsa-miR-1259:PITA hsa-miR-1259:PITA_TOP PITA 2.88E-08 1.53E-04 8.13E-08 7.44E-07 18 312 "NLN,ARHGAP5,NEDD8,PCDH9,PGGT1B,PREPL,CEP135,RAN,NTN4,MBNL2,ELF1,ZCCHC8,NBEA,ERBIN,PCDH17,STRN,KCNT2,ZBTB41" MicroRNA hsa-miR-532-3p:TargetScan hsa-miR-532-3p TargetScan 2.88E-08 1.53E-04 8.13E-08 7.44E-07 16 244 "MDM4,CADM3,NEDD8,NFKBIA,HECTD1,PIGG,RAN,EFNA5,NMNAT2,ATP8A2,NFASC,PPARGC1A,HSP90B1,PLB1,FAM49A,PABPN1" MicroRNA hsa-miR-542-5p:mirSVR_lowEffct hsa-miR-542-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.98E-08 1.59E-04 8.42E-08 7.71E-07 22 464 "ULK1,APAF1,PDE6B,GPR180,MATR3,PARPBP,OGFOD2,RGS12,CLIP1,TMEM156,N4BP2L2,FBXO11,ZNF446,SLC22A4,INSM2,ADGRA3,NCSTN,NSD2,PLB1,ZBED3-AS1,DNAH10,AXDND1" MicroRNA hsa-miR-3139:mirSVR_highEffct hsa-miR-3139:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-08 1.60E-04 8.48E-08 7.77E-07 27 676 "ACOX3,SLAMF6,PNP,PCCA,ATAD2B,LTB4R,PREPL,SNCAIP,FAM169A,SNX17,BIVM,COG3,PTGS2,RASA1,RNASE2,TXNDC15,ETF1,FOXO1,VEZT,SLC22A4,MYO16,GABRA2,OXGR1,CRB1,FAM151B,CHPT1,RMST" MicroRNA hsa-miR-155-5p:TargetScan hsa-miR-155-5p TargetScan 3.10E-08 1.65E-04 8.75E-08 8.01E-07 20 387 "APC,ASTN1,NOVA1,CAMK4,ATAD2B,PRKD1,G3BP2,DHFR,ELK3,FGF9,FLT1,FBXO11,G2E3,KDM5B,NFASC,GOLGA3,GRSF1,MSH6,DCP2,IL6ST" MicroRNA hsa-miR-361-5p:TargetScan hsa-miR-361-5p TargetScan 3.22E-08 1.71E-04 9.08E-08 8.31E-07 15 214 "MDM4,BTF3,CDK17,CFL2,GPR180,HOMER1,RCHY1,MTX3,DNMT3A,ARGLU1,RNF4,ELOVL7,ATP6V0A2,HMGCR,LAD1" MicroRNA hsa-miR-1278:PITA hsa-miR-1278:PITA_TOP PITA 3.30E-08 1.75E-04 9.30E-08 8.52E-07 14 184 "PITPNM2,PPFIA4,FAM193A,RILPL1,UHMK1,TAPT1,TBC1D4,G3BP2,BRMS1L,NR5A2,ATP8A2,ERBIN,GRSF1,BAZ1A" MicroRNA hsa-miR-4297:mirSVR_highEffct hsa-miR-4297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-08 1.84E-04 9.76E-08 8.93E-07 25 593 "WDR19,STXBP6,AACS,PNP,PCK2,RGSL1,LACC1,UBXN2A,RABGAP1L,DHFR,MEMO1,EIF2B1,FCGR2B,SLC34A2,YPEL5,KDM5B,ADGRL3,TFDP1,TMEM174,ZNF550,STARD4,ANKS1B,NPHS2,AXDND1,LMNB1" MicroRNA hsa-miR-718:mirSVR_lowEffct hsa-miR-718:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-08 1.86E-04 9.83E-08 9.00E-07 18 316 "CUL4A,NFKBIA,CDK18,THAP6,NGDN,RAN,MEMO1,EFS,PCGF3,GORAB,FOXO1,HSD17B7,C5orf56,TCF7,PLB1,ZBTB41,PGAM5,SPRYD7" MicroRNA hsa-miR-491-5p:mirSVR_highEffct hsa-miR-491-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.58E-08 1.91E-04 1.01E-07 9.23E-07 28 727 "MDM4,BCL2L2,CBLN3,CD1E,CDK18,PDGFRA,PFKFB2,THAP6,COPA,DHFR,FAM129A,ABCA11P,FLT3,ZNF605,CYP1B1-AS1,MYT1L,CIDEB,KDM5B,KDM3B,NFASC,MCCC2,INSM2,C5orf56,TCF7,ADAMTS19,PAPPA2,KCNT2,ZFHX2" MicroRNA hsa-miR-140-3p.2:TargetScan hsa-miR-140-3p.2 TargetScan 3.60E-08 1.92E-04 1.01E-07 9.28E-07 19 353 "NFATC4,NOVA1,MPZL1,FCRLB,CENPC,EGLN3,MEMO1,LATS2,FGF9,FOXG1,PCDH17,ADAM17,METAP2,GPR12,DOCK9,MSH6,RASSF6,HPCAL1,KIF2A" MicroRNA "CTGAGCC,MIR-24:MSigDB" "CTGAGCC,MIR-24:MSigDB" MSigDB 3.64E-08 1.94E-04 1.02E-07 9.37E-07 15 216 "BCL2L2,NFXL1,PDGFRA,MATR3,KLHL3,RASA1,TNFRSF19,FGFR3,DCAF11,KIF21B,PCDH17,KMT5C,XPO4,ATP6V0A2,NSD2" MicroRNA hsa-miR-4753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.66E-08 1.95E-04 1.03E-07 9.42E-07 18 317 "ASCL1,MYBPC1,CD84,PIK3C2B,NUP37,UGT2B28,LRRTM2,ATG10,ATP6AP1L,FOXO1,PLEKHA6,N4BP2,CENPJ,XPO4,MSH6,TMEM174,IGF1,LHX9" MicroRNA hsa-miR-1296:mirSVR_lowEffct hsa-miR-1296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.70E-08 1.97E-04 1.04E-07 9.51E-07 29 774 "RALGAPA1,ABL2,MDM4,CUL4A,XPR1,CHIT1,KIAA0040,CMTM5,COG3,NR1I3,RB1,CRYL1,EIF2D,SLC22A17,FBXO11,SLC12A2,SLC22A5,DCAF11,MYO16,TMEM183A,ZNF274,ANKLE2,ADGRA3,CRB1,HMGCR,HTR2A,ZNF470,PLB1,LAD1" MicroRNA hsa-let-7a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.74E-08 1.99E-04 1.05E-07 9.63E-07 26 639 "MDM4,BIRC6,SLC5A6,CFL2,SNX6,BRI3BP,CEP135,SNX17,DHX9,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,NDUFAF7,FNIP1,SFSWAP,G2E3,POTEM,JPH4,ZBTB37,STRN,LILRB4,GPN1,LTA4H,SKA3" MicroRNA hsa-miR-181a-5p:Functional MTI Functional MTI miRTarbase 3.78E-08 2.01E-04 1.06E-07 9.71E-07 24 553 "TMEM132B,ULK1,RGS5,ZNF664,PDGFRA,PFKFB2,LYSMD3,PTGS2,NUDT12,G3BP2,MTX3,RAN,ATG10,STX2,DRAM1,FBXO11,BRMS1L,MRPS14,ZNF667,ADAM17,RASSF6,RAB2B,HSP90B1,NSD2" MicroRNA hsa-miR-600:PITA hsa-miR-600:PITA_TOP PITA 3.81E-08 2.03E-04 1.07E-07 9.79E-07 16 249 "MAP1B,APBB2,NOVA1,ATAD2B,BOD1L1,GNPTAB,DNM3,TNFRSF19,FOXG1,FOXO1,NBEA,MYT1L,ATP6V0A2,SPTSSA,SPRYD7,CDK2AP1" MicroRNA "CTTTGCA,MIR-527:MSigDB" "CTTTGCA,MIR-527:MSigDB" MSigDB 3.87E-08 2.06E-04 1.09E-07 9.93E-07 15 217 "ULK1,NOVA1,CACNA1E,DCLK1,PITX1,GNPTAB,PRKD1,MBNL2,TBC1D19,NBEA,IVNS1ABP,NFASC,ATP11A,KLF12,PABPN1" MicroRNA hsa-miR-887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-08 2.06E-04 1.09E-07 9.94E-07 22 471 "MATN3,MDM4,PIGR,CLOCK,BRI3BP,UBXN2A,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,ZCCHC8,ZBTB37,GOLGA3,COX18,IGF1,ZNF324B,PGAM5,FAM151B,LAD1,ZDHHC20" MicroRNA hsa-miR-558:mirSVR_highEffct hsa-miR-558:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.94E-08 2.09E-04 1.10E-07 1.01E-06 25 597 "TBC1D14,ULK1,BTF3,CDK17,PKP1,HECTD1,NGDN,TINF2,G3BP2,NR1I3,DNMT3A,MARVELD2,ETF1,GMPR2,PCGF3,TOMM40L,VEZT,DDX51,CGREF1,MYO16,PDS5B,NPAS3,KLHL20,TGM1,AP4S1" MicroRNA hsa-miR-371-3p:mirSVR_highEffct hsa-miR-371-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.01E-08 2.13E-04 1.12E-07 1.03E-06 10 83 "ATP6V1G3,CDK18,EPGN,FCAR,CYP1B1-AS1,MYT1L,IL6ST,KIR2DL4,KIR3DL2,AXDND1" MicroRNA hsa-miR-4284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.11E-08 2.18E-04 1.15E-07 1.05E-06 26 642 "MDM4,TBC1D14,APAF1,RILPL1,FAM177A1,PDE6B,CCDC122,PIGR,STRN3,LRRTM2,SLC35F6,DTD2,TMEM33,ZNF419,ARSK,VEZT,SH3BP2,BRMS1L,UHRF1BP1L,ADAM17,GOLGA3,ACSL6,TEP1,ATP6V0A2,IGF1,ZDHHC20" MicroRNA hsa-let-7d*:mirSVR_lowEffct hsa-let-7d*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.52E-08 2.40E-04 1.26E-07 1.16E-06 20 396 "MDM4,MSH2,STARD13,FGFRL1,BCL2L2,NOVA1,TAF1B,CDK17,VIT,NUP37,HECTD1,THAP6,DNM3,ZFYVE16,MATR3,FAM172A,SH3YL1,FLT1,SLC22A4,ZNF470" MicroRNA hsa-miR-224-5p:TargetScan hsa-miR-224-5p TargetScan 4.64E-08 2.47E-04 1.30E-07 1.19E-06 18 322 "MAP1B,PPFIA4,ATP2B4,KCTD12,BCL2L2,CAST,GPR180,POU2F1,FBXL5,MBNL2,ACIN1,ATP11A,ADAM17,PPIP5K2,GPN1,HMGCR,DCP2,IL6ST" MicroRNA hsa-miR-23b-3p:Functional MTI Functional MTI miRTarbase 4.64E-08 2.47E-04 1.30E-07 1.19E-06 18 322 "MAP1B,CUL4A,RGS5,MCFD2,COPA,VCAN,G3BP2,SUPT7L,RB1,TLR6,FNIP1,ERBIN,ADAM17,MSH6,ZNF550,DCP2,ZMYM2,LMNB1" MicroRNA hsa-miR-31*:mirSVR_highEffct hsa-miR-31*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.70E-08 2.50E-04 1.31E-07 1.20E-06 19 359 "RALGAPA1,AP1G2,PNP,CCNB1,PCCA,ZMYM5,ZNF595,LINC01085,ADGRF3,CEP350,MAEA,FCGR3A,FNIP1,SLC34A2,TMEM183A,RBKS,IKBIP,CRB1,JCHAIN" MicroRNA hsa-miR-517c:mirSVR_lowEffct hsa-miR-517c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-08 2.50E-04 1.31E-07 1.20E-06 20 397 "APBB2,CDK17,HECTD1,LYSMD3,GALNT9,MATR3,PTPRH,RB1,OGFOD2,RGS12,EFNA5,DLEU1,F7,FLT1,IVNS1ABP,SLC12A2,SLC15A4,PPIP5K2,XPO4,CDK2AP1" MicroRNA hsa-miR-7106-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.86E-08 2.58E-04 1.35E-07 1.24E-06 29 784 "MATN3,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,SAP18,FNIP1,ZCCHC8,NLRP2,POTEM,DCAF11,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-130a-3p:Functional MTI Functional MTI miRTarbase 4.90E-08 2.61E-04 1.37E-07 1.25E-06 20 398 "MCC,STARD13,PDGFRA,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,ERBIN,PPARGC1A,GRSF1,GPR161,UBC,SLAIN1,TENT2,IRF1,LMLN" MicroRNA hsa-miR-181d-5p:Functional MTI Functional MTI miRTarbase 4.98E-08 2.65E-04 1.39E-07 1.27E-06 17 288 "ULK1,FCHO2,ZNF664,G3BP2,MTX3,RAN,BORA,STX2,DRAM1,FBXO11,MRPS14,ZNF667,DHRS4,ADAM17,RAB2B,HSP90B1,NSD2" MicroRNA hsa-miR-4304:mirSVR_lowEffct hsa-miR-4304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.01E-08 2.67E-04 1.40E-07 1.28E-06 22 478 "SFTA3,KIAA1211,TBC1D14,NCOA1,KCTD12,LDB2,FCGR2C,EPGN,SNCAIP,CSNK1G3,RB1,CLIP1,FOXG1,PAICS,IVNS1ABP,THADA,YPEL5,UHRF1BP1L,PPARGC1A,BAZ1A,YTHDC2,PLB1" MicroRNA hsa-miR-25*:mirSVR_lowEffct hsa-miR-25*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.03E-08 2.67E-04 1.40E-07 1.28E-06 28 739 "ADD1,PPFIA4,APBB2,MSH2,ZNF784,NCOA1,CENPBD1P1,MYH6,ZNF595,PIGR,SNX6,CLOCK,NCOR2,PTPRC,TINF2,C14orf119,FAM228A,RNASEL,LGR6,FCAR,RELL1,POLK,SLC22A4,DRC1,TADA2B,MFSD2B,LCP1,NUAK2" MicroRNA hsa-miR-4308:mirSVR_highEffct hsa-miR-4308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.20E-08 2.77E-04 1.45E-07 1.32E-06 22 479 "PPP1R12B,CD84,SCFD2,RGSL1,C12orf65,RABGAP1L,RNF219,NR1H4,EGLN3,ARGLU1,DTD2,GUSBP3,TXNDC15,SNORA49,ELOVL7,RELL1,NFASC,CCDC169,RMST,LMNB1,PABPN1,SPATA13" MicroRNA hsa-miR-10b:mirSVR_highEffct hsa-miR-10b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.27E-08 2.80E-04 1.47E-07 1.34E-06 24 563 "KIAA1211,COG6,ARL1,STARD13,KCTD12,CCNA1,ZNF595,LYSMD3,NCOR2,ARSK,STK32B,SDC1,UFM1,CCDC88A,ZNF667,TMEM183A,HSPH1,NPAS3,GOLGA3,C1QTNF9B,BAZ1A,HMGCR,SLAIN1,RMST" MicroRNA hsa-miR-6788-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.33E-08 2.83E-04 1.48E-07 1.36E-06 23 521 "MATN3,PPFIA4,CCNB1IP1,PIGR,BRI3BP,UBXN2A,CEP120,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,PCGF3,ZCCHC8,ZBTB37,GOLGA3,COX18,IGF1,ZNF324B,PGAM5,FAM151B,LETM1" MicroRNA hsa-miR-122:mirSVR_highEffct hsa-miR-122:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.41E-08 2.88E-04 1.50E-07 1.38E-06 25 607 "MDM4,ZNF664,TAPT1,POU2F1,EPGN,GNPDA2,CWC27,TNFRSF19,RELL1,FTLP10,SUPT20H,ALKAL2,POTEM,LIMCH1,NPAS3,KLHL20,GTF3C2,ATP6V0A2,ZNF324B,IL6ST,PLB1,KIF3C,KIR2DL1,KIR3DL1,KIR3DL2" MicroRNA hsa-miR-487b:mirSVR_highEffct hsa-miR-487b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.43E-08 2.89E-04 1.51E-07 1.38E-06 13 162 "ZNF664,AKAP6,CEP350,ZNF219,CLIP1,SLC15A4,SLC22A4,NAAA,LRCH1,PSME4,ARHGEF28,VRK2,AXDND1" MicroRNA hsa-miR-145:PITA hsa-miR-145:PITA_TOP PITA 5.54E-08 2.95E-04 1.54E-07 1.41E-06 20 401 "NLN,SEMA6A,ARHGAP5,CFL2,ATAD2B,DNM3,F11R,MTX3,RASA1,NTN4,TOMM40L,FGFR3,FOXO1,IVNS1ABP,PPIP5K2,DOCK9,TENT2,DCP2,TMEM178A,LOX" MicroRNA hsa-miR-3186-5p:mirSVR_lowEffct hsa-miR-3186-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.54E-08 2.95E-04 1.54E-07 1.41E-06 20 401 "WDR35,FAM193A,ATP7B,JAKMIP1,FAM169A,ZNF586,PIGG,NTN4,F10,ARL6IP4,TNFRSF19,PIBF1,SUCO,KIF21B,ZNF544,UTP20,GOLGA3,CNTN2,TFDP1,KIF3C" MicroRNA hsa-miR-532-5p:PITA hsa-miR-532-5p:PITA_TOP PITA 5.55E-08 2.95E-04 1.54E-07 1.41E-06 15 223 "MAP1B,CAST,NFXL1,PCDH9,DCLK1,PCSK1,DHX9,SUCO,FOXO1,NBEA,SLC8A1,NR5A2,PDS5B,PCDH17,KLF12" MicroRNA hsa-miR-184:mirSVR_lowEffct hsa-miR-184:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.68E-08 3.02E-04 1.57E-07 1.44E-06 21 441 "ADD1,ZNF784,ARHGEF7,FCRLB,DCLK1,PDGFRA,NCOR2,KIAA0040,ARGLU1,FAM81B,SAP18,MAEA,TMEM132D,C1orf112,LIMCH1,KIF21B,COP1,CRB1,PAPPA2,ZBTB41,KIF3C" MicroRNA "CAGTGTT,MIR-200A:MSigDB" "CAGTGTT,MIR-200A:MSigDB" MSigDB 5.79E-08 3.08E-04 1.60E-07 1.47E-06 17 291 "SEMA6A,APBB2,PCDH9,CDK17,SLC25A3,NRXN1,EPN1,CSNK1G3,DMXL1,PCGF3,YPEL5,MYT1L,PDS5B,NMNAT2,NFASC,STRN,NSD2" MicroRNA "CAGTGTT,MIR-141:MSigDB" "CAGTGTT,MIR-141:MSigDB" MSigDB 5.79E-08 3.08E-04 1.60E-07 1.47E-06 17 291 "SEMA6A,APBB2,PCDH9,CDK17,SLC25A3,NRXN1,EPN1,CSNK1G3,DMXL1,PCGF3,YPEL5,MYT1L,PDS5B,NMNAT2,NFASC,STRN,NSD2" MicroRNA hsa-miR-181c-5p:Functional MTI Functional MTI miRTarbase 5.79E-08 3.08E-04 1.60E-07 1.47E-06 17 291 "NDRG2,ULK1,ZNF664,G3BP2,MTX3,RAN,LATS2,STX2,DRAM1,FBXO11,MRPS14,ZNF667,ADAM17,RAB2B,HSP90B1,NSD2,KIT" MicroRNA hsa-miR-609:mirSVR_highEffct hsa-miR-609:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.90E-08 3.14E-04 1.63E-07 1.49E-06 21 442 "CARMIL3,ARHGEF7,CBLN3,RILPL1,PCCA,WDFY2,C1orf116,RB1,RNF4,SELP,UFM1,CCDC88A,NAAA,CD244,CFHR4,STRN,KMT5C,ZBTB49,BAZ1A,PLB1,TDRD3" MicroRNA hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 6.00E-08 3.19E-04 1.66E-07 1.52E-06 20 403 "MATN3,MCFD2,APBB2,STARD13,UHMK1,PKP1,ITSN2,MTX3,RNF219,KLHL12,FCAR,CCDC92,SLC22A5,MRPS27,EML4,RASSF6,HSP90B1,TENT2,TPTE2,DCP2" MicroRNA hsa-miR-651-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-08 3.32E-04 1.72E-07 1.58E-06 15 225 "SNX24,LYSMD3,DCAF8,CLIP4,KDM5B,OXGR1,SRP54,PSME4,GOLGA3,EML4,UBC,TADA2B,ZMYM2,LMNB1,SPATA13" MicroRNA hsa-miR-708:mirSVR_highEffct hsa-miR-708:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.28E-08 3.34E-04 1.73E-07 1.59E-06 28 747 "ACOX3,SLAMF6,PNP,CAST,ZMYM5,ATAD2B,CLOCK,PREPL,SNCAIP,FAM169A,SNX17,BIVM,COG3,DCT,PTGS2,RNASE2,ETF1,FOXO1,VEZT,SLC22A5,MYO16,RBKS,CRB1,TMPO,MAEL,TPO,PAPPA2,TTC41P" MicroRNA hsa-miR-1286:mirSVR_highEffct hsa-miR-1286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.32E-08 3.36E-04 1.74E-07 1.60E-06 23 526 "ZMYM5,CFL2,ZNF595,COPA,EGLN3,LRPPRC,DCUN1D2,TRAPPC12,FBXO11,ACIN1,NAAA,DRC1,PCDH17,LPIN1,CNTN2,C1QTNF9B,FCRLA,HEXB,ADAMTS19,ZNF876P,SDR39U1,DNAH10,RMST" MicroRNA hsa-miR-377-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.41E-08 3.41E-04 1.77E-07 1.62E-06 24 569 "NOP14,PPP1R12B,RILPL1,CCNB1,GNPTAB,TTC37,MTX3,SUPT7L,SLC35F6,TMEM33,TXNDC15,MARVELD2,STX2,CCDC38,FNIP1,BRMS1L,MRPS14,COX18,ATP6V0A2,HSP90B1,GUF1,IGF1,C12orf73,PGAM5" MicroRNA hsa-miR-936:PITA hsa-miR-936:PITA_TOP PITA 6.57E-08 3.50E-04 1.81E-07 1.66E-06 16 259 "MCC,FAM193A,NEDD8,CAD,SCARB1,CFL2,LRRTM2,KLHL3,TBC1D4,LATS2,CCDC88A,PDS5B,ERBIN,PCDH17,IGF1,ZMYM2" MicroRNA hsa-miR-194-5p:TargetScan hsa-miR-194-5p TargetScan 6.71E-08 3.57E-04 1.85E-07 1.69E-06 18 330 "BIRC6,HOMEZ,PITPNM2,ARHGAP5,PDE4D,CFL2,CHD1,ATAD2B,MATR3,CEP350,NOP9,DNMT3A,MBNL2,BRMS1L,LIMCH1,KDM5B,PPARGC1A,IL6ST" MicroRNA hsa-miR-299-3p:mirSVR_highEffct hsa-miR-299-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.73E-08 3.58E-04 1.85E-07 1.70E-06 25 614 "ADD1,APC,ATP4B,ZNF664,CHIT1,WDFY2,NRXN1,PIGR,CSNK1G3,FBXL5,PARPBP,GALNT14,RGS4,MPHOSPH9,VEZT,PKD2L2,YPEL5,MYT1L,KDM5B,LRCH1,IKBIP,BRD8,TMED2,GALP,FAM71C" MicroRNA hsa-miR-1260:PITA hsa-miR-1260:PITA_TOP PITA 6.74E-08 3.59E-04 1.86E-07 1.70E-06 13 165 "MAP1B,NEDD8,XPR1,ATAD2B,HECTD1,DNMT3A,SUCO,FLT3,NMNAT2,KDM3B,PPARGC1A,ZNF544,PABPN1" MicroRNA hsa-miR-1909:mirSVR_highEffct hsa-miR-1909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.76E-08 3.60E-04 1.86E-07 1.70E-06 23 528 "ADD1,COG6,NYNRIN,ATP12A,RILPL1,RCBTB2,UGT2B28,TINF2,GALNT14,ATG10,EIF2B1,PEAR1,TMEM132D,CIDEB,JPH4,MCCC2,CRB1,HSP90B1,IL25,TPTE2,KIR2DL4,TTC41P,FAM71C" MicroRNA hsa-miR-337-5p:mirSVR_lowEffct hsa-miR-337-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.92E-08 3.68E-04 1.90E-07 1.74E-06 19 368 "ATAD2B,HECTD1,THTPA,SNCAIP,VCAN,MPHOSPH8,PRKD1,EPS8L1,ABCA11P,CLIP1,TOMM40L,TNFRSF19,YPEL5,TMEM183A,NPAS3,ATP11A,XPO4,AP4S1,UBE2K" MicroRNA hsa-miR-4755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-08 3.75E-04 1.94E-07 1.77E-06 17 295 "ABL2,APAF1,ATP1A2,AKAP6,UBXN2A,DMXL1,RABGAP1L,ZNF329,TRIM28,TLR6,PCBD2,PEAR1,SH3BP2,POTEM,KIF21B,ZBTB37,ATP6V0A2" MicroRNA hsa-miR-634:mirSVR_highEffct hsa-miR-634:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.27E-08 3.87E-04 2.00E-07 1.83E-06 26 661 "NRL,UHMK1,RFLNA,CKMT2,SNX6,PM20D1,BIVM,PIGG,G3BP2,RASA1,ARGLU1,KLHL12,PCGF3,NDUFAF7,FLT1,MBIP,UFM1,SLC12A2,NPAS3,SRP72,MCCC2,PAPPA2,FCRL6,CCDC169,ZMYM2,LTA4H" MicroRNA hsa-miR-6875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.31E-08 3.89E-04 2.01E-07 1.84E-06 16 261 "RALGAPA1,RGS5,ASCL1,ATP1A2,KCTD12,ZNF664,UGT2B28,EPGN,MATR3,FAM81B,TRAPPC13,GORAB,GABRB1,PCDH17,ACSL6,ZDHHC20" MicroRNA hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.40E-08 3.93E-04 2.03E-07 1.86E-06 21 448 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-30c-1-3p:Functional MTI Functional MTI miRTarbase 7.49E-08 3.98E-04 2.05E-07 1.88E-06 23 531 "MATN3,PPFIA4,CCNB1IP1,PIGR,BRI3BP,UBXN2A,CEP120,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,PCGF3,ZCCHC8,ZBTB37,GOLGA3,COX18,IGF1,ZNF324B,PGAM5,FAM151B,LETM1" MicroRNA hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 7.68E-08 4.08E-04 2.10E-07 1.93E-06 21 449 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-1277:mirSVR_highEffct hsa-miR-1277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.68E-08 4.08E-04 2.10E-07 1.93E-06 21 449 "SFTA3,KIAA1211,PCDH9,PFKFB2,GPR180,CEP135,PTPRH,DNMT3A,RNASEL,TRAPPC12,SNORA53,PIBF1,G2E3,TADA1,UGGT2,GABRB1,PDS5B,NAAA,ACSL6,TENT2,CHPT1" MicroRNA hsa-miR-1826:PITA hsa-miR-1826:PITA_TOP PITA 7.75E-08 4.12E-04 2.12E-07 1.94E-06 14 197 "SEMA6A,NOVA1,FCHO2,DCLK1,XPR1,HOMER1,MTX3,MEMO1,NBEA,MYT1L,PDS5B,NPAS3,BAZ1A,ZBTB41" MicroRNA hsa-miR-92a-1*:mirSVR_highEffct hsa-miR-92a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.99E-08 4.25E-04 2.19E-07 2.00E-06 22 491 "PPFIA4,STARD13,ATP7B,AP1G2,CD1E,RGSL1,WDFY2,AKAP6,GNPTAB,WDR1,SLC22A17,FCGR3A,FCGR3B,FMO1,TM9SF1,JPH4,NAAA,PPIP5K2,ADGRL3,MAEL,ZBTB41,TMEM178A" MicroRNA hsa-let-7i-5p:Functional MTI Functional MTI miRTarbase 8.04E-08 4.27E-04 2.20E-07 2.01E-06 18 334 "MDM4,EP400,ASCL1,SLC5A6,BRI3BP,CEP135,SNX17,CEP120,MTX3,EGLN3,TBC1D19,PCGF3,TOMM40L,POTEM,KDM5B,ZBTB37,STRN,IGF1" MicroRNA hsa-miR-1280:mirSVR_lowEffct hsa-miR-1280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.18E-08 4.35E-04 2.24E-07 2.05E-06 19 372 "WDR19,AMDHD1,PCK2,CENPC,HECTD1,COPA,NCOR2,DNMT3A,EIF2D,PCBD2,FGF9,FLT3,MEGF10,KDM3B,NEDD1,TNR,ADAMTS19,ZFHX2,PABPN1" MicroRNA hsa-miR-769-3p:mirSVR_highEffct hsa-miR-769-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.27E-08 4.40E-04 2.26E-07 2.07E-06 22 492 "KIAA1211,SLAMF6,NOVA1,FCGR2C,GPR180,SNCAIP,COG3,CLIP4,RNASE2,POLK,CCDC92,LIMCH1,NAAA,ANKLE2,TMED2,ADAM17,C5orf56,GTF3C2,HSP90B1,HPCAL1,LINC00272,RMST" MicroRNA hsa-miR-4635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.40E-08 4.47E-04 2.29E-07 2.10E-06 18 335 "KIAA1211,ATP6V1G3,RGS5,CDKL2,PCDH9,CLOCK,KLHL3,TMEM33,CWC27,BRMS1L,NUBPL,OXGR1,ERBIN,KLHL20,ARHGEF28,MSH6,HAL,GUF1" MicroRNA hsa-miR-6840-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.58E-08 4.57E-04 2.34E-07 2.14E-06 21 452 "APAF1,NOP14,MPHOSPH8,SPATA18,MTX3,ZNF329,RGS12,TMEM33,POLR1D,TBC1D19,CCDC38,RUBCNL,BRMS1L,ACSL6,SNRNP35,ATP6V0A2,GPN1,GUF1,IGF1,PGAM5,LETM1" MicroRNA hsa-miR-940:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.78E-08 4.67E-04 2.39E-07 2.19E-06 27 713 "MATN3,HOMEZ,APAF1,NOP14,CDK18,CFL2,PIGR,UBXN2A,MPHOSPH8,EIF2AK2,SNX17,SLC35F6,IPO4,DTD2,MARVELD2,TBC1D19,ARSK,ETF1,DLEU1,UTP15,SH3BP2,SLC30A6,GABRB1,RAPGEF6,GRSF1,PGAM5,LETM1" MicroRNA hsa-miR-630:PITA hsa-miR-630:PITA_TOP PITA 8.79E-08 4.67E-04 2.40E-07 2.19E-06 14 199 "PCDH9,PDGFRA,CFL2,CEP350,KLHL3,RELL1,FOXG1,FOXO1,NPAS3,KDM3B,PSME4,KLF12,HMGCR,ZBTB41" MicroRNA hsa-miR-3115:mirSVR_highEffct hsa-miR-3115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.86E-08 4.71E-04 2.41E-07 2.21E-06 25 623 "MAP1B,CDKL4,STARD13,FCRL3,ZNF664,RCBTB2,DHRS1,LTB4R,C1orf116,POU2F1,EPGN,BIVM,SREK1,PTGS2,VEZT,IVNS1ABP,TADA1,CCDC88A,MIMT1,PSME4,TBC1D1,PLB1,ZBED3-AS1,RMST,LOX" MicroRNA "TTGCACT,MIR-130A:MSigDB" "TTGCACT,MIR-130A:MSigDB" MSigDB 8.90E-08 4.73E-04 2.42E-07 2.22E-06 19 374 "BIRC6,PITPNM2,NCOA1,STARD13,PDGFRA,CLOCK,G3BP2,WDR1,ARGLU1,ELK3,MPHOSPH9,NBEA,CCDC88A,ERBIN,KLHL20,ATP11A,TENT2,IRF1,KIT" MicroRNA "TTGCACT,MIR-130B:MSigDB" "TTGCACT,MIR-130B:MSigDB" MSigDB 8.90E-08 4.73E-04 2.42E-07 2.22E-06 19 374 "BIRC6,PITPNM2,NCOA1,STARD13,PDGFRA,CLOCK,G3BP2,WDR1,ARGLU1,ELK3,MPHOSPH9,NBEA,CCDC88A,ERBIN,KLHL20,ATP11A,TENT2,IRF1,KIT" MicroRNA "TTGCACT,MIR-301:MSigDB" "TTGCACT,MIR-301:MSigDB" MSigDB 8.90E-08 4.73E-04 2.42E-07 2.22E-06 19 374 "BIRC6,PITPNM2,NCOA1,STARD13,PDGFRA,CLOCK,G3BP2,WDR1,ARGLU1,ELK3,MPHOSPH9,NBEA,CCDC88A,ERBIN,KLHL20,ATP11A,TENT2,IRF1,KIT" MicroRNA hsa-miR-103a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 8.91E-08 4.74E-04 2.42E-07 2.22E-06 21 453 "ABL2,MDM4,SEMA6A,CUL4A,MYBPC1,FGFRL1,CDK17,PDE4D,GPR180,CFAP45,CSNK1G3,VCAN,SREK1,G3BP2,ARGLU1,CLIP1,VEZT,IVNS1ABP,GABRB1,EML4,FAM49A" MicroRNA hsa-miR-520e:Functional MTI Functional MTI miRTarbase 8.91E-08 4.74E-04 2.42E-07 2.22E-06 21 453 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-15b-5p:Functional MTI Functional MTI miRTarbase 8.94E-08 4.75E-04 2.43E-07 2.22E-06 28 760 "ABL2,TBC1D14,MCFD2,DHX37,UVSSA,CDK17,PDE4D,GPR180,TM9SF2,PIK3C2B,POU2F1,NCOR2,EIF2AK2,SREK1,DHFR,PXMP2,TMEM161B,CLIP4,LRPPRC,SBNO1,MPHOSPH9,FOXO1,IVNS1ABP,PPIP5K2,COP1,AP4S1,TADA2B,SELENOI" MicroRNA hsa-miR-485-5p:mirSVR_highEffct hsa-miR-485-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.97E-08 4.77E-04 2.44E-07 2.23E-06 30 855 "WDR35,NOVA1,CAD,CD1D,PCK2,RGSL1,PDGFRA,ZNF595,POLE,THTPA,NTN4,FCAMR,ABCA11P,PIBF1,SELP,NBEA,RAPGEF6,RBKS,KLHL20,PPARGC1A,GJB2,UTP20,GOLGA3,ANO4,FCRLA,CRB1,TGFBI,GTF2H3,TTC41P,LINC00442" MicroRNA hsa-miR-150:PITA hsa-miR-150:PITA_TOP PITA 9.35E-08 4.97E-04 2.54E-07 2.32E-06 14 200 "MAP1B,APC,CAST,ATAD2B,TAPT1,KLHL3,ETF1,NBEA,TADA1,KDM5B,PPARGC1A,TDG,GTF3C2,HSP90B1" MicroRNA hsa-miR-3646:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.35E-08 4.97E-04 2.54E-07 2.32E-06 14 200 "MYBPC1,KCTD12,PDE4D,GNPTAB,TOGARAM2,POU2F1,EIF2AK2,NUDT12,G3BP2,GABRB1,TDG,TFDP1,SELENOI,ZDHHC20" MicroRNA hsa-miR-606:PITA hsa-miR-606:PITA_TOP PITA 9.40E-08 5.00E-04 2.55E-07 2.33E-06 17 301 "RALGAPA1,SFTA3,ARL1,SLC4A4,GPR180,BOD1L1,GNPTAB,CSNK1G3,MATR3,MPHOSPH9,TBC1D19,SCYL2,CCDC88A,SRP54,PPARGC1A,MTUS2,TDG" MicroRNA hsa-miR-299-5p:PITA hsa-miR-299-5p:PITA_TOP PITA 9.57E-08 5.09E-04 2.59E-07 2.38E-06 13 170 "ARHGAP5,PFKFB2,LRRTM2,PTGS2,G3BP2,TMEM161B,MAEA,ETF1,FOXG1,CCDC88A,MEGF10,IQGAP2,KLF12" MicroRNA hsa-miR-520b:Functional MTI Functional MTI miRTarbase 9.58E-08 5.10E-04 2.59E-07 2.38E-06 21 455 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 9.58E-08 5.10E-04 2.59E-07 2.38E-06 21 455 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA "CTCTAGA,MIR-518F:MSigDB" "CTCTAGA,MIR-518F:MSigDB" MSigDB 9.66E-08 5.13E-04 2.61E-07 2.39E-06 8 50 "BCL2L2,SLC25A3,EGLN3,ARGLU1,FLT3,JPH4,GTF3C2,KLF12" MicroRNA "CTCTAGA,MIR-526A:MSigDB" "CTCTAGA,MIR-526A:MSigDB" MSigDB 9.66E-08 5.13E-04 2.61E-07 2.39E-06 8 50 "BCL2L2,SLC25A3,EGLN3,ARGLU1,FLT3,JPH4,GTF3C2,KLF12" MicroRNA "CTCTAGA,MIR-526C:MSigDB" "CTCTAGA,MIR-526C:MSigDB" MSigDB 9.66E-08 5.13E-04 2.61E-07 2.39E-06 8 50 "BCL2L2,SLC25A3,EGLN3,ARGLU1,FLT3,JPH4,GTF3C2,KLF12" MicroRNA hsa-miR-518c:mirSVR_lowEffct hsa-miR-518c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.73E-08 5.17E-04 2.63E-07 2.41E-06 26 671 "SFTA3,MAP1B,LRRC43,ADD1,NRL,SNTG2,PFKFB2,NRXN1,TAPT1,ZNF586,SNX17,SREK1,DMXL1,MEMO1,CRYL1,MARVELD2,DNAJC27,N4BP2L2,MYT1L,MCCC2,MAST4,RNF212,RIMBP2,ADAMTS19,RMST,LMNB1" MicroRNA hsa-miR-1246:PITA hsa-miR-1246:PITA_TOP PITA 9.85E-08 5.24E-04 2.66E-07 2.43E-06 15 233 "ATP6V1G3,SEMA6A,BCL2L2,LDB2,NRXN1,AKAP6,LRRTM2,MBNL2,ETF1,CCDC88A,SLC12A2,NR5A2,METAP2,SLAIN1,ZBTB41" MicroRNA hsa-miR-100:mirSVR_lowEffct hsa-miR-100:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.95E-08 5.29E-04 2.68E-07 2.46E-06 14 201 "MAP1B,BIRC6,CDK7,ZNF595,UBXN2A,OGFOD2,DLEU1,NDUFAF7,LRRN2,FBXO11,NLRP2,MYO16,MEGF10,TMPO" MicroRNA hsa-miR-1182:mirSVR_highEffct hsa-miR-1182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-07 5.48E-04 2.78E-07 2.54E-06 25 628 "NLN,SLAMF6,CUL4A,CCNB1IP1,CAST,DCLK1,WDFY2,AKAP6,COG3,TSEN15,RGS4,TM9SF1,NUBPL,IVNS1ABP,SLC22A4,ERAP1,TBC1D1,INSM2,ANO4,NT5C1B,LTB4R2,ZNF470,CHPT1,DIAPH3,RNASE11" MicroRNA hsa-miR-297:PITA hsa-miR-297:PITA_TOP PITA 1.04E-07 5.54E-04 2.81E-07 2.57E-06 15 234 "BIRC6,NCOA1,CAMK4,NRXN1,HOMER1,STRN3,DNMT3A,NTN4,MBNL2,ETF1,CLIP1,SUCO,CCDC88A,ANO4,NSD2" MicroRNA hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA_TOP PITA 1.05E-07 5.57E-04 2.82E-07 2.59E-06 18 340 "MDM4,CUL4A,ARHGAP5,ATP2B4,MPZL1,FCHO2,CFL2,ATAD2B,BRI3BP,MBNL2,IVNS1ABP,CCDC88A,MYT1L,NFASC,PCDH17,LPIN1,XPO4,TMEM178A" MicroRNA hsa-miR-891b:PITA hsa-miR-891b:PITA_TOP PITA 1.05E-07 5.58E-04 2.83E-07 2.59E-06 16 268 "RILPL1,LDB2,XPR1,CDK17,CEBPE,DMXL1,KLHL3,TMEM161B,SUCO,CCDC88A,SLC12A2,MYT1L,NMNAT2,GTF3C2,RIMBP2,ZMYM2" MicroRNA hsa-miR-103-as:mirSVR_highEffct hsa-miR-103-as:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-07 5.69E-04 2.88E-07 2.64E-06 21 458 "RGS5,MSH2,B4GALT3,PCK2,HECTD1,TAPT1,ZNF586,PARPBP,TMEM161B,UGT2A3,TNFRSF19,NBEA,PDS5B,BRD8,MAST4,TDG,GTF3C2,TPO,YTHDC2,KCNT2,KIF2A" MicroRNA hsa-miR-507:PITA hsa-miR-507:PITA_TOP PITA 1.08E-07 5.76E-04 2.91E-07 2.67E-06 17 304 "ARHGAP5,NCOA1,CAMK4,PCDH9,SLC25A3,HOMER1,SREK1,DMXL1,POLR1D,FOXO1,SCYL2,PCDH17,DHRS4,ADAM17,ADGRL3,ANO4,XPO4" MicroRNA hsa-miR-1208:PITA hsa-miR-1208:PITA_TOP PITA 1.08E-07 5.76E-04 2.91E-07 2.67E-06 17 304 "ABL2,MAP1B,ASTN1,ATP2B4,SNX6,ATAD2B,HECTD1,STRN3,DEPDC4,CCDC88A,MYT1L,PDS5B,JPH4,PCDH17,METAP2,RIMBP2,ZBTB41" MicroRNA hsa-miR-557:PITA hsa-miR-557:PITA_TOP PITA 1.08E-07 5.76E-04 2.91E-07 2.67E-06 17 304 "ARHGAP5,NCOA1,CAMK4,PCDH9,SLC25A3,HOMER1,SREK1,DMXL1,POLR1D,FOXO1,SCYL2,PCDH17,DHRS4,ADAM17,ADGRL3,ANO4,XPO4" MicroRNA hsa-miR-548az-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-07 5.87E-04 2.97E-07 2.72E-06 16 269 "MCC,RGS5,FCHO2,CCNB1,PFKFB2,THAP6,GNPTAB,TOGARAM2,POU2F1,CLOCK,RAN,FAM129A,CLIP4,PACRGL,SUCO,KDM5B" MicroRNA hsa-miR-548t-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-07 5.87E-04 2.97E-07 2.72E-06 16 269 "MCC,RGS5,FCHO2,CCNB1,PFKFB2,THAP6,GNPTAB,TOGARAM2,POU2F1,CLOCK,RAN,FAM129A,CLIP4,PACRGL,SUCO,KDM5B" MicroRNA hsa-miR-1976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-07 6.01E-04 3.03E-07 2.78E-06 22 501 "ABL2,SLC4A4,BCL2L2,RILPL1,PIWIL1,THAP6,CEP135,RABGAP1L,SLC35F6,ZNF329,ATP6AP1L,FCAR,VEZT,DDX51,BRMS1L,ZNF667,UGGT2,SPIC,RASSF6,GPN1,TXK,FAM151B" MicroRNA hsa-miR-629:mirSVR_highEffct hsa-miR-629:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-07 6.04E-04 3.05E-07 2.79E-06 28 769 "RALGAPA1,FCHO2,FAM177A1,SLC25A3,PIGR,STRN3,EPGN,LYSMD3,CEP350,PPP2R3C,RNASEL,EFS,PCBD2,POLK,FMO1,G2E3,PLEKHA6,SLC8A1,YPEL5,COMMD6,METAP2,YIPF7,TMPO,HEXB,TENT2,PLB1,ZBED3-AS1,CHPT1" MicroRNA hsa-miR-601:mirSVR_highEffct hsa-miR-601:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-07 6.05E-04 3.05E-07 2.79E-06 19 380 "TMEM132B,CARMIL3,BCL2L2,RAB29,CCDC122,TBC1D4,TINF2,PARPBP,ATG10,REST,PACRGL,LGR6,PPARGC1A,ADGRL3,RAB2B,GUF1,PLB1,ANKS1B,RNASE11" MicroRNA hsa-miR-3925-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-07 6.06E-04 3.06E-07 2.80E-06 11 117 "NUP37,G3BP2,WDR1,RNASEL,TRIM28,FOXO1,TM9SF1,ATP8A2,ZBTB37,RAB2B,NUAK2" MicroRNA hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 1.15E-07 6.11E-04 3.08E-07 2.82E-06 21 460 "MAP1B,ULK1,BCL2L2,POU2F1,BRI3BP,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,REST,CLIP4,SBNO1,N4BP2L2,SUCO,ZNF446,FAM114A1,ADAM17,GTF2H3,TXK" MicroRNA hsa-miR-1273e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-07 6.11E-04 3.08E-07 2.82E-06 21 460 "APAF1,NOP14,ASTN1,FCHO2,ZNF664,PCCA,MPHOSPH8,SLC35F6,POLR1D,FCAMR,TCTN2,TBC1D19,TRAPPC13,PEAR1,SLC8A1,SNRNP35,GRSF1,HSP90B1,UBE2K,GUF1,PGAM5" MicroRNA hsa-miR-30c-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-07 6.12E-04 3.08E-07 2.82E-06 23 544 "MATN3,PPFIA4,CCNB1IP1,PIGR,BRI3BP,UBXN2A,CEP120,ZNF329,DTD2,TMEM33,TCTN2,TBC1D19,ARSK,PCGF3,ZCCHC8,ZBTB37,GOLGA3,COX18,IGF1,ZNF324B,PGAM5,FAM151B,LETM1" MicroRNA hsa-miR-1295:mirSVR_lowEffct hsa-miR-1295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-07 6.18E-04 3.11E-07 2.84E-06 16 270 "CEBPE,TM9SF2,SNX6,STRN3,DCAF8,POLR1D,SNORA49,ARSK,DNAJC27,TOMM40L,HSPH1,DOCK9,VRK2,CENPH,IL6ST,LHX9" MicroRNA hsa-miR-744-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-07 6.19E-04 3.11E-07 2.85E-06 15 236 "TMEM132B,CD1D,PIWIL1,CSNK1G3,ARGLU1,SBNO1,ATP6AP1L,ZNF446,COMMD6,ZBTB37,TEP1,GRSF1,GPR161,ZNF84,PGAM5" MicroRNA hsa-miR-6086:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-07 6.32E-04 3.18E-07 2.91E-06 23 545 "NOP14,PPP1R12B,RILPL1,CCNB1,GNPTAB,MTX3,SUPT7L,SLC35F6,TMEM33,TXNDC15,MARVELD2,STX2,CCDC38,FNIP1,BRMS1L,MRPS14,COX18,ATP6V0A2,HSP90B1,GUF1,IGF1,C12orf73,PGAM5" MicroRNA hsa-miR-1470:mirSVR_lowEffct hsa-miR-1470:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-07 6.34E-04 3.18E-07 2.91E-06 21 461 "ADORA1,ARL1,FAM193A,PTPRVP,SNX17,SREK1,PTPRH,DNMT3A,PACRGL,MARVELD2,SUCO,FLT1,STAB2,CGREF1,ADGRL3,TNR,MZF1,PLB1,SPTSSA,KIR2DS4,LMNB1" MicroRNA "AACTGAC,MIR-223:MSigDB" "AACTGAC,MIR-223:MSigDB" MSigDB 1.20E-07 6.40E-04 3.21E-07 2.94E-06 10 93 "MAP1B,CDK17,PDE4D,SACS,RASA1,RNF4,RUBCNL,SLC8A1,PDS5B,IL6ST" MicroRNA hsa-miR-519b-3p:Functional MTI Functional MTI miRTarbase 1.25E-07 6.63E-04 3.33E-07 3.05E-06 18 344 "MAP1B,MCC,FCHO2,CFL2,GNPTAB,POU2F1,BRI3BP,UBXN2A,FBXL5,RAN,EGLN3,FAM129A,RB1,CLIP4,FAM114A1,ZBTB37,UBC,ZDHHC20" MicroRNA hsa-miR-1306-5p:TargetScan hsa-miR-1306-5p TargetScan 1.27E-07 6.75E-04 3.38E-07 3.10E-06 14 205 "NDRG2,HOMEZ,APC,ATP1A2,BCL2L2,LDB2,KLHL3,DNMT3A,F10,MYT1L,INSM2,CAB39L,KIR2DL4,PABPN1" MicroRNA hsa-miR-4722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-07 6.81E-04 3.41E-07 3.12E-06 21 463 "ABL2,ADD1,SLC4A4,RILPL1,PIWIL1,THAP6,CEP135,RABGAP1L,DNMT3A,ZNF329,FCAR,VEZT,DDX51,BRMS1L,ZNF667,UGGT2,SPIC,RASSF6,GPN1,TXK,FAM151B" MicroRNA hsa-miR-551b:mirSVR_lowEffct hsa-miR-551b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-07 6.83E-04 3.42E-07 3.13E-06 16 272 "ACOX3,NOP14,ADGRD1,ITGBL1,TAPT1,SPATA18,NR1H4,DNMT3A,RNF31,EIF2B1,ETF1,ABCA11P,N4BP2L2,TADA1,RNF17,YTHDC2" MicroRNA hsa-miR-4649-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 6.89E-04 3.45E-07 3.16E-06 22 505 "MATN3,HOMEZ,APAF1,NOP14,CAD,PDE6B,MPHOSPH8,EIF2AK2,DTD2,MARVELD2,TBC1D19,ARSK,UTP15,TOMM40L,SH3BP2,PLEKHA6,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5" MicroRNA hsa-miR-1279:PITA hsa-miR-1279:PITA_TOP PITA 1.30E-07 6.90E-04 3.45E-07 3.16E-06 15 238 "MAP1B,PDE4D,PDGFRA,SMIM14,SACS,G3BP2,GNPDA2,MBNL2,ELK3,FAM172A,ALKAL2,ANO4,DOCK9,XPO4,IGF1" MicroRNA hsa-miR-203a-3p:Functional MTI Functional MTI miRTarbase 1.31E-07 6.94E-04 3.47E-07 3.18E-06 17 308 "HOMEZ,MCFD2,BCL2L2,CDKL2,HECTD1,CLOCK,UBXN2A,SPATA18,FBXL5,RAN,PEAR1,GABRB1,ARHGEF28,HTR2A,ZMYM2,KIF2A,SPATA13" MicroRNA hsa-miR-720:mirSVR_lowEffct hsa-miR-720:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-07 7.06E-04 3.53E-07 3.23E-06 21 464 "DDX55,ATP1A2,STARD13,ARHGEF7,SNX6,TAPT1,POLE,POU2F1,SNX17,DHFR,WDR1,EGLN3,OGFOD2,HSD17B7,RBKS,GJA3,RNF212,HPCAL1,TMEM178A,KIR2DS4,SPATA13" MicroRNA hsa-miR-875-5p:mirSVR_highEffct hsa-miR-875-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.37E-07 7.28E-04 3.64E-07 3.33E-06 26 683 "MDM4,CCNB1,PDE4D,ITGBL1,AKAP6,STRN3,RCHY1,LYSMD3,DNM3,COG3,CEP120,OCIAD1,SUPT7L,SETDB2,PACRGL,SH3YL1,PCBD2,FCAR,MBIP,SCYL2,N4BP2,YPEL5,LIMCH1,MCCC2,ZMYM2,SPRYD7" MicroRNA hsa-miR-6727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-07 7.31E-04 3.65E-07 3.34E-06 21 465 "ABL2,ADD1,SLC4A4,RILPL1,PIWIL1,THAP6,CEP135,RABGAP1L,DNMT3A,ZNF329,FCAR,VEZT,DDX51,BRMS1L,ZNF667,UGGT2,SPIC,RASSF6,GPN1,TXK,FAM151B" MicroRNA hsa-miR-185:PITA hsa-miR-185:PITA_TOP PITA 1.43E-07 7.60E-04 3.79E-07 3.47E-06 14 207 "ABL2,ARHGAP5,CARMIL3,PCDH9,CSNK1G3,KLHL3,COCH,PARPBP,PDS5B,NMNAT2,KDM3B,COP1,NSD2,KIF3C" MicroRNA hsa-miR-3613-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-07 7.62E-04 3.80E-07 3.48E-06 22 508 "CCNB1IP1,ZNF664,CFL2,CHD1,PIK3C2B,HECTD1,GNPTAB,NGDN,MTX3,RAN,SH3BP2,UHRF1BP1L,UTP20,PPIP5K2,GOLGA3,SPIC,COX18,ATP6V0A2,DCP2,CENPH,SPTSSA,LMNB1" MicroRNA hsa-miR-4293:mirSVR_highEffct hsa-miR-4293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-07 7.62E-04 3.80E-07 3.48E-06 22 508 "MSH2,ARHGAP5,NCOA1,NOVA1,CFL2,CHD1,LYSMD3,SNORA53,MARVELD2,ABCA11P,CLIP1,FGF9,HSPH1,DRC1,PSME4,ADGRA3,RNF17,CRB1,LINC01551,RAB2B,MAEL,ZMYM2" MicroRNA hsa-miR-518f:mirSVR_lowEffct hsa-miR-518f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-07 7.73E-04 3.85E-07 3.53E-06 24 595 "SFTA3,MAP1B,LRRC43,NRL,SNTG2,PFKFB2,NRXN1,TAPT1,ZNF586,SNX17,SREK1,DMXL1,MEMO1,CRYL1,MARVELD2,N4BP2L2,MYT1L,MCCC2,MAST4,RNF212,RIMBP2,ADAMTS19,RMST,LMNB1" MicroRNA hsa-miR-938:mirSVR_highEffct hsa-miR-938:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-07 7.80E-04 3.88E-07 3.56E-06 20 426 "APAF1,LINC02347,CDKL2,PCCA,SNCAIP,ZNF586,SACS,SUPT7L,NTN4,N4BP2L2,POLK,VEZT,ARHGEF40,HSPH1,KLHL20,LPIN1,ADGRL3,ADAMTS19,GUF1,STARD4" MicroRNA hsa-miR-935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-07 7.87E-04 3.92E-07 3.59E-06 11 120 "POU2F1,MTX3,DHFR,PXMP2,FOXO1,FLT1,G2E3,NBEA,SLC12A2,KDM3B,TFDP1" MicroRNA hsa-miR-518c:mirSVR_highEffct hsa-miR-518c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.49E-07 7.93E-04 3.95E-07 3.61E-06 16 275 "CD1E,ZNF664,AKAP6,LOC439933,WDR1,DNMT3A,CLIP4,LATS2,DLEU1,GMPR2,USP44,GORAB,ZCCHC8,FBXO11,LPIN1,TXK" MicroRNA hsa-miR-519a-3p:Functional MTI Functional MTI miRTarbase 1.54E-07 8.21E-04 4.08E-07 3.74E-06 18 349 "MAP1B,MCC,FCHO2,CFL2,GNPTAB,POU2F1,BRI3BP,UBXN2A,FBXL5,RAN,EGLN3,FAM129A,RB1,CLIP4,FAM114A1,ZBTB37,UBC,ZDHHC20" MicroRNA hsa-miR-624:PITA hsa-miR-624:PITA_TOP PITA 1.57E-07 8.33E-04 4.14E-07 3.79E-06 16 276 "MCC,HOMEZ,CUL4A,CHAMP1,CDK17,PDGFRA,PIK3C2B,CEP350,RASA1,NBEA,MYT1L,PCDH17,ADGRL3,KMT5C,IGF1,PABPN1" MicroRNA hsa-miR-1253:PITA hsa-miR-1253:PITA_TOP PITA 1.57E-07 8.33E-04 4.14E-07 3.79E-06 16 276 "ABL2,CACNA1E,CDK17,DNM3,ZFYVE16,RGS4,MEMO1,SLC22A5,CHFR,JPH4,NPAS3,ADGRL3,EML4,GTF3C2,TMEM178A,PABPN1" MicroRNA hsa-miR-519c-3p:Functional MTI Functional MTI miRTarbase 1.61E-07 8.57E-04 4.25E-07 3.89E-06 18 350 "MAP1B,MCC,FCHO2,CFL2,GNPTAB,POU2F1,BRI3BP,UBXN2A,FBXL5,RAN,EGLN3,FAM129A,RB1,CLIP4,FAM114A1,ZBTB37,UBC,ZDHHC20" MicroRNA hsa-miR-193a-3p:mirSVR_highEffct hsa-miR-193a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.64E-07 8.73E-04 4.33E-07 3.96E-06 21 470 "NFATC4,NOVA1,SMIM14,TAPT1,SREK1,NUDT12,DNMT3A,EGLN3,ATG10,MEMO1,MROH9,CCDC88A,RAPGEF6,DRC1,ERBIN,PPARGC1A,GPR12,ADAMTS19,ZMYM2,RMST,IFT88" MicroRNA hsa-miR-409-5p:mirSVR_lowEffct hsa-miR-409-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-07 8.75E-04 4.34E-07 3.97E-06 27 736 "WDR19,CENPBD1P1,CAST,PAH,RGSL1,PFKFB2,CCDC122,NRXN1,THAP6,HOMER1,NUDT12,SLC35F6,RGS4,RGS12,DHRS2,TBC1D19,ARL6IP4,USP44,NDUFAF7,POLK,FOXG1,NBEA,PDS5B,NFASC,TMPO,HAL,TENT2" MicroRNA hsa-miR-1282:mirSVR_lowEffct hsa-miR-1282:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.67E-07 8.85E-04 4.39E-07 4.02E-06 26 690 "RALGAPA1,ATP4B,KCTD12,NOVA1,PAH,RFLNA,PCDH9,FAM177A1,ATAD2B,AKAP6,STRN3,MPC2,CEP135,SUPT7L,NR1H4,RASA1,POLR1D,MPHOSPH9,TBC1D19,PIBF1,STAB2,SCYL2,IKBIP,ADGRL3,CRB1,ZMYM2" MicroRNA "TAATGTG,MIR-323:MSigDB" "TAATGTG,MIR-323:MSigDB" MSigDB 1.69E-07 8.98E-04 4.45E-07 4.08E-06 12 149 "MCFD2,SLC4A4,FCHO2,PCDH9,CSNK1G3,ARGLU1,SUCO,PPARGC1A,ANO4,TMPO,NSD2,NUAK2" MicroRNA hsa-miR-323-5p:mirSVR_highEffct hsa-miR-323-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.70E-07 9.03E-04 4.47E-07 4.09E-06 19 390 "SLAMF6,ATP6V1G3,BLZF1,ATP12A,CHD1,ANAPC4,GNPTAB,ITSN2,NR1H4,RASA1,FAM172A,ABCA11P,COMMD6,CRB1,TNR,UBE2K,GPN1,PGAM5,SPRYD7" MicroRNA hsa-miR-379:mirSVR_highEffct hsa-miR-379:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.70E-07 9.03E-04 4.47E-07 4.09E-06 19 390 "ACOX3,ATP1A2,B4GALT3,SLC5A6,CCNB1,CDK17,DNM3,RABGAP1L,FAM129A,RNASEL,ZCCHC8,CCDC88A,GABRB1,HSPH1,PCDH17,ADGRL3,LINC01551,IL6ST,KIR2DS4" MicroRNA hsa-miR-1300:PITA hsa-miR-1300:PITA_TOP PITA 1.73E-07 9.19E-04 4.55E-07 4.16E-06 16 278 "ABL2,PITPNM2,PPFIA4,HECTD1,ZFYVE16,CEP350,RGS4,EFNA5,NR5A2,CHFR,PSME4,TBC1D1,EML4,KHNYN,UBE2K,LMNB1" MicroRNA hsa-miR-410-3p:TargetScan hsa-miR-410-3p TargetScan 1.77E-07 9.39E-04 4.65E-07 4.25E-06 20 431 "CUL4A,MCFD2,APAF1,ARHGAP5,CFL2,PRKD1,MATR3,DNMT3A,RNF4,ELK3,FGFR3,ARHGEF40,RAPGEF6,ATP11A,PPIP5K2,KLF12,PAPPA2,HTR2A,IGF1,KIT" MicroRNA "AAGCCAT,MIR-135A:MSigDB" "AAGCCAT,MIR-135A:MSigDB" MSigDB 1.80E-07 9.54E-04 4.71E-07 4.32E-06 17 315 "NCOA1,ATP2B4,KCTD12,ARHGEF7,CACNA1E,FCHO2,PGGT1B,ELK3,FOXO1,SFSWAP,NBEA,MYT1L,RAPGEF6,ANO4,KMT5C,IL6ST,LCP1" MicroRNA hsa-miR-139-5p:TargetScan hsa-miR-139-5p TargetScan 1.80E-07 9.54E-04 4.71E-07 4.32E-06 17 315 "NDRG2,MCFD2,KCTD12,PCDH9,PDE4D,PGGT1B,HOMER1,DNM3,FOXO1,NR5A2,GABRB1,KDM3B,PPARGC1A,PSME4,ATP11A,MSH6,HMGCR" MicroRNA "AAGCCAT,MIR-135B:MSigDB" "AAGCCAT,MIR-135B:MSigDB" MSigDB 1.80E-07 9.54E-04 4.71E-07 4.32E-06 17 315 "NCOA1,ATP2B4,KCTD12,ARHGEF7,CACNA1E,FCHO2,PGGT1B,ELK3,FOXO1,SFSWAP,NBEA,MYT1L,RAPGEF6,ANO4,KMT5C,IL6ST,LCP1" MicroRNA hsa-miR-625*:mirSVR_highEffct hsa-miR-625*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-07 9.55E-04 4.72E-07 4.32E-06 24 602 "RALGAPA1,SMIM15,CAMK4,FCHO2,UHMK1,SNTG2,NUP37,THAP6,RCHY1,DCT,ATG10,SMC6,LAP3,LRPPRC,SLC34A2,IVNS1ABP,HSPH1,ADAM17,RIMBP2,TECRL,STARD4,YTHDC2,CHPT1,RNASE11" MicroRNA hsa-miR-4316:mirSVR_highEffct hsa-miR-4316:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.83E-07 9.74E-04 4.81E-07 4.40E-06 20 432 "ZNF542P,FCHO2,PFKFB2,CCDC122,SNCAIP,EIF2AK2,SPATA18,RABGAP1L,SMC6,N4BP2L2,SLC22A5,CIDEB,ERAP1,NPAS3,ZBTB37,PPARGC1A,ANO4,ADAMTS19,GPN1,LETM1" MicroRNA hsa-miR-6873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-07 9.77E-04 4.81E-07 4.41E-06 19 392 "MDM4,NLN,COG6,ASCL1,PPP1R3E,SMIM14,POU2F1,LRRTM2,ATG10,KLHL12,ATP6AP1L,FGF9,PLEKHA6,ZNF667,LIMCH1,PCDH17,STRN,GALP,LHX9" MicroRNA hsa-miR-4286:mirSVR_highEffct hsa-miR-4286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.84E-07 9.77E-04 4.81E-07 4.41E-06 19 392 "RALGAPA1,ADD1,SLC4A4,STRN3,BRI3BP,NOS1AP,SREK1,CEP350,NR1I3,GALNT14,LAP3,BORA,DLEU1,TOMM40L,VEZT,RBKS,ADGRL3,MAEL,POC5" MicroRNA hsa-miR-28-5p:mirSVR_highEffct hsa-miR-28-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.85E-07 9.84E-04 4.85E-07 4.44E-06 25 648 "ACOX3,SLAMF6,PNP,FCHO2,ZMYM5,ATAD2B,PREPL,SNCAIP,FAM169A,SNX17,BIVM,PIGG,COG3,PTGS2,EGLN3,RNASE2,ETF1,FOXO1,VEZT,ZCCHC8,MYO16,TFDP1,ANKS1B,FAM151B,EP400P1" MicroRNA hsa-miR-205:PITA hsa-miR-205:PITA_TOP PITA 1.90E-07 1.01E-03 4.98E-07 4.56E-06 16 280 "NCOA1,SLC4A4,KCTD12,XPR1,CFL2,DMXL1,OCIAD1,ETF1,CLIP1,IVNS1ABP,N4BP2,SNRPF,JPH4,KHNYN,XPO4,KLF12" MicroRNA hsa-miR-101-3p:Functional MTI Functional MTI miRTarbase 1.91E-07 1.02E-03 5.00E-07 4.58E-06 19 393 "MSH2,CHAMP1,PIK3C2B,POU2F1,LYSMD3,TTC37,PTGS2,RNF219,DNMT3A,MBNL2,VEZT,FBXO11,KDM3B,UGT2A1,SNRNP35,GRSF1,KLF12,HSP90B1,LMNB1" MicroRNA hsa-miR-103:PITA hsa-miR-103:PITA_TOP PITA 2.06E-07 1.10E-03 5.39E-07 4.94E-06 19 395 "ABL2,SEMA6A,CUL4A,ARHGAP5,NOVA1,DCLK1,CHD1,CLOCK,LATS2,TBC1D19,CLIP1,GABRB1,PCDH17,TMED2,PPIP5K2,ADGRL3,XPO4,NSD2,ZMYM2" MicroRNA hsa-miR-107:PITA hsa-miR-107:PITA_TOP PITA 2.06E-07 1.10E-03 5.39E-07 4.94E-06 19 395 "ABL2,SEMA6A,CUL4A,ARHGAP5,NOVA1,DCLK1,CHD1,CLOCK,LATS2,TBC1D19,CLIP1,GABRB1,PCDH17,TMED2,PPIP5K2,ADGRL3,XPO4,NSD2,ZMYM2" MicroRNA hsa-miR-301a-3p:Functional MTI Functional MTI miRTarbase 2.06E-07 1.10E-03 5.39E-07 4.94E-06 19 395 "MCC,STARD13,CAD,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,GAK,ERBIN,GRSF1,GPR161,UBC,TENT2,IRF1,LMLN" MicroRNA hsa-miR-665:TargetScan hsa-miR-665 TargetScan 2.07E-07 1.10E-03 5.40E-07 4.95E-06 18 356 "PPP1R12B,NEDD8,NFATC4,POLE,POU2F1,DNMT3A,BORA,DRAM1,FGF9,SDC1,CCDC92,DCAF11,KIF21B,JPH4,ATP8A2,METAP2,KHNYN,GSX2" MicroRNA hsa-miR-935:PITA hsa-miR-935:PITA_TOP PITA 2.10E-07 1.11E-03 5.47E-07 5.01E-06 16 282 "HOMEZ,CUL4A,PITPNM2,APC,SMIM14,HOMER1,LYSMD3,CSNK1G3,DNM3,LATS2,MBNL2,FBXO11,HSPH1,MTUS2,ACSL6,ZBTB41" MicroRNA hsa-miR-518a-3p:mirSVR_lowEffct hsa-miR-518a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-07 1.12E-03 5.49E-07 5.03E-06 23 563 "SFTA3,LRRC43,ARHGAP5,NRL,SNTG2,PFKFB2,NRXN1,TAPT1,ZNF586,SNX17,SREK1,MEMO1,MARVELD2,DRAM1,N4BP2L2,POTEM,MCCC2,MAST4,RNF212,RIMBP2,ADAMTS19,KLF12,LMNB1" MicroRNA hsa-miR-454-3p:Functional MTI Functional MTI miRTarbase 2.15E-07 1.14E-03 5.59E-07 5.12E-06 19 396 "MCC,STARD13,KCTD12,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,ERBIN,GRSF1,GPR161,UBC,TENT2,SPTSSA,IRF1,LMLN" MicroRNA hsa-miR-576-3p:PITA hsa-miR-576-3p:PITA_TOP PITA 2.15E-07 1.14E-03 5.60E-07 5.13E-06 14 214 "APBB2,FCHO2,HOMER1,STRN3,TAPT1,PTGS2,STX2,SLC8A1,MYT1L,KDM3B,PPARGC1A,STON1,DOCK9,GRSF1" MicroRNA hsa-miR-573:PITA hsa-miR-573:PITA_TOP PITA 2.15E-07 1.14E-03 5.60E-07 5.13E-06 14 214 "MAP1B,BIRC6,PGGT1B,RASA1,MBNL2,PCGF3,KDM5B,ERBIN,PSME4,TMED2,KLF12,IGF1,KCNN2,KIT" MicroRNA hsa-miR-125b-5p:TargetScan hsa-miR-125b-5p TargetScan 2.20E-07 1.17E-03 5.72E-07 5.23E-06 25 654 "ABL2,APC,BLZF1,PPP1R12B,BCL2L2,CAMK4,CHAMP1,SCARB1,NRXN1,PIK3C2B,NCOR2,GALNT14,REST,SBNO1,CGREF1,NR5A2,ADAM17,MTUS2,ACSL6,KHNYN,GRSF1,NPL,HMGCR,LHX9,KCNJ9" MicroRNA hsa-miR-125a-5p:TargetScan hsa-miR-125a-5p TargetScan 2.20E-07 1.17E-03 5.72E-07 5.23E-06 25 654 "ABL2,APC,BLZF1,PPP1R12B,BCL2L2,CAMK4,CHAMP1,SCARB1,NRXN1,PIK3C2B,NCOR2,GALNT14,REST,SBNO1,CGREF1,NR5A2,ADAM17,MTUS2,ACSL6,KHNYN,GRSF1,NPL,HMGCR,LHX9,KCNJ9" MicroRNA hsa-miR-122-5p:Functional MTI Functional MTI miRTarbase 2.21E-07 1.18E-03 5.76E-07 5.27E-06 24 609 "ABL2,MDM4,EP400,AACS,ATP1A2,STARD13,BCL2L2,PFKFB2,THAP6,COPA,HEATR5A,BRI3BP,PIGG,DMXL1,GNPDA2,EGLN3,SBNO1,NMNAT2,LPIN1,ADAM17,TEP1,GRSF1,GPR161,UBE2K" MicroRNA hsa-miR-149-5p:Functional MTI Functional MTI miRTarbase 2.23E-07 1.19E-03 5.80E-07 5.31E-06 19 397 "TBC1D14,PIWIL1,PITX1,ITSN2,LRRTM2,MATR3,DHX9,SLC35F6,RAN,RB1,RGS12,ZNF419,TRIM28,ARSK,TACC3,SDC1,GJA3,ADAM17,KHNYN" MicroRNA hsa-miR-615-3p:Functional MTI Functional MTI miRTarbase 2.26E-07 1.20E-03 5.86E-07 5.37E-06 30 893 "BIRC6,CUL4A,EP400,DDX55,ZNF784,ATP7B,CHAMP1,SCARB1,TM9SF2,GNPTAB,ZFYVE16,MATR3,COCH,WDR1,RAN,TMEM33,KIRREL1,SUPT20H,TM9SF1,NMNAT2,TMED2,MSH6,TMPO,HMGCR,UBC,TENT2,NSD2,IL6ST,KIF2A,PABPN1" MicroRNA hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA_TOP PITA 2.28E-07 1.21E-03 5.91E-07 5.41E-06 14 215 "WDR66,PDE4D,ATAD2B,CSNK1G3,DNM3,LATS2,PCGF3,NPAS3,GJA3,EML4,KHNYN,RIMBP2,KLF12,LHX9" MicroRNA hsa-miR-329:PITA hsa-miR-329:PITA_TOP PITA 2.28E-07 1.21E-03 5.91E-07 5.41E-06 14 215 "WDR66,PDE4D,ATAD2B,CSNK1G3,DNM3,LATS2,PCGF3,NPAS3,GJA3,EML4,KHNYN,RIMBP2,KLF12,LHX9" MicroRNA hsa-miR-548c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-07 1.21E-03 5.91E-07 5.41E-06 22 522 "MYBPC1,SLC5A6,CDKL2,FCHO2,UHMK1,GPR180,PIK3C2B,NUP37,GNPTAB,MTX3,RNF219,ZNF329,REST,CLIP4,CWC27,SH3BP2,SLC15A4,NEDD1,EML4,GRSF1,LMNB1,SPATA13" MicroRNA "TGTGTGA,MIR-377:MSigDB" "TGTGTGA,MIR-377:MSigDB" MSigDB 2.40E-07 1.28E-03 6.23E-07 5.71E-06 13 184 "CUL4A,NCOA1,PDGFRA,PRKD1,RASA1,ARGLU1,TM9SF1,NBEA,THADA,PSME4,TMED2,GRSF1,NSD2" MicroRNA hsa-miR-33a-5p:TargetScan hsa-miR-33a-5p TargetScan 2.41E-07 1.28E-03 6.24E-07 5.71E-06 19 399 "MDM4,ADD1,MCFD2,NCOA1,NOVA1,CACNA1E,CAMK4,PDE4D,PDGFRA,CHD1,ITGBL1,NRXN1,DCAF8,RASA1,SBNO1,MYT1L,ANO4,RIMBP2,HMGCR" MicroRNA hsa-miR-33b-5p:TargetScan hsa-miR-33b-5p TargetScan 2.41E-07 1.28E-03 6.24E-07 5.71E-06 19 399 "MDM4,ADD1,MCFD2,NCOA1,NOVA1,CACNA1E,CAMK4,PDE4D,PDGFRA,CHD1,ITGBL1,NRXN1,DCAF8,RASA1,SBNO1,MYT1L,ANO4,RIMBP2,HMGCR" MicroRNA hsa-let-7e-5p:Functional MTI Functional MTI miRTarbase 2.42E-07 1.29E-03 6.26E-07 5.73E-06 24 612 "MDM4,SLC5A6,BRI3BP,CEP135,DCAF8,MATR3,PSMA6,SNX17,CEP120,MTX3,ZNF256,TBC1D19,PCGF3,UTP15,TOMM40L,THADA,POTEM,ZBTB37,STRN,PSME4,TENT2,IGF1,LMLN,SPATA13" MicroRNA hsa-miR-193a-5p:mirSVR_highEffct hsa-miR-193a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-07 1.29E-03 6.29E-07 5.76E-06 22 524 "SFTA3,MDM4,NLN,CUL4A,NOVA1,PNP,DCLK1,WDFY2,LTB4R,LYSMD3,CSNK1G3,ABCA11P,SCYL2,SLC22A4,MRPS27,LRCH1,COMMD6,ANO4,NT5C1B,TMPO,HAL,KCNN2" MicroRNA hsa-miR-410-3p:Functional MTI Functional MTI miRTarbase 2.45E-07 1.30E-03 6.34E-07 5.80E-06 15 250 "MCFD2,DDX55,MYBPC1,CCNB1,UHMK1,POU2F1,LYSMD3,REST,MBNL2,EIF2B1,CCDC38,PLEKHA6,SLC8A1,SRP72,TFDP1" MicroRNA hsa-let-7e*:mirSVR_highEffct hsa-let-7e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.64E-07 1.40E-03 6.82E-07 6.25E-06 10 101 "ADD1,COG6,ZNF542P,FGFRL1,GPR180,NUP37,AASDH,SNRPF,RAB2B,TECRL" MicroRNA hsa-miR-670-3p:TargetScan hsa-miR-670-3p TargetScan 2.70E-07 1.43E-03 6.97E-07 6.38E-06 19 402 "MDM4,APBB2,NCOA1,KCTD12,EIF2AK2,MEMO1,RNASEL,SBNO1,BRMS1L,POTEM,FSHR,KDM5B,ERAP1,GJA3,CNTN2,GPR12,DCP2,IL6ST,PABPN1" MicroRNA hsa-miR-500:PITA hsa-miR-500:PITA_TOP PITA 2.79E-07 1.48E-03 7.20E-07 6.59E-06 17 325 "ABL2,CUL4A,SLC4A4,ATP2B4,KCTD12,FCHO2,CHD1,STRN3,RCHY1,G3BP2,CCDC88A,SLC12A2,PDS5B,KDM3B,ERBIN,ZBTB41,TMEM178A" MicroRNA hsa-miR-615-5p:mirSVR_highEffct hsa-miR-615-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-07 1.48E-03 7.20E-07 6.59E-06 17 325 "B4GALT3,PCCA,PDGFRA,LTB4R,SNCAIP,TINF2,RGS4,GUSBP3,MARVELD2,FCAMR,CWC27,FCAR,SUCO,LILRB1,ZNF544,LILRB4,CDK2AP1" MicroRNA hsa-miR-1179:PITA hsa-miR-1179:PITA_TOP PITA 2.85E-07 1.52E-03 7.36E-07 6.74E-06 15 253 "TMEM132B,ARHGAP5,ASCL1,ZNF595,LYSMD3,SREK1,TOMM40L,MYT1L,PPARGC1A,TMED2,METAP2,SLAIN1,ZNF470,ZMYM2,ZBTB41" MicroRNA hsa-miR-873-5p.2:TargetScan hsa-miR-873-5p.2 TargetScan 2.87E-07 1.52E-03 7.39E-07 6.77E-06 18 364 "MAP1B,KIAA1211,CADM3,NOVA1,CBLN3,RILPL1,GPR180,LTB4R,POU2F1,LACC1,NOS1AP,MATR3,KLHL3,FAM129A,FBXO11,NPAS3,KDM3B,PCDH17" MicroRNA hsa-miR-410:PITA hsa-miR-410:PITA_TOP PITA 2.87E-07 1.52E-03 7.39E-07 6.77E-06 18 364 "ULK1,ARHGAP5,PPP1R12B,FCHO2,CHD1,RCHY1,LYSMD3,PRKD1,MATR3,SACS,NTN4,PCGF3,SLC34A2,PCDH17,PSME4,PPIP5K2,DOCK9,IGF1" MicroRNA hsa-miR-3144-5p:mirSVR_lowEffct hsa-miR-3144-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.87E-07 1.53E-03 7.40E-07 6.77E-06 32 1004 "ADD1,MMP17,SNX24,DHX37,ZNF784,ATP1A2,CADM3,MYH6,SNTG2,ADGRF3,PMCH,TOGARAM2,SNX17,SPATA18,COG3,ZNF219,FGFR3,TACC3,PIBF1,JPH4,NAAA,ZNF274,NPAS3,MRPS27,RBKS,TCF7,CRB1,TECRL,NSD2,ZNF10,ZMYM2,LINC01913" MicroRNA hsa-miR-1281:mirSVR_lowEffct hsa-miR-1281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-07 1.53E-03 7.42E-07 6.79E-06 24 618 "UVSSA,BTF3,RFLNA,GLT1D1,FAM53A,C12orf65,ZFYVE16,RB1,ZNF329,POLR1D,GP6,C1orf112,SLC22A5,KIF21B,LPIN1,ZNF544,UTP20,ANO4,TFDP1,NPL,FIP1L1,LETM1,RMST,IFT88" MicroRNA hsa-miR-1915:mirSVR_highEffct hsa-miR-1915:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.93E-07 1.56E-03 7.54E-07 6.90E-06 20 445 "NCOA1,PDGFRA,SPATA18,TSEN15,TRAPPC12,TRAPPC13,TOMM40L,FOXG1,RUBCNL,WDCP,ACIN1,YIPF7,SLC7A8,RAB2B,ARHGAP30,GUF1,ZFHX2,ZNF470,FAM151B,TTC41P" MicroRNA hsa-miR-7160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-07 1.56E-03 7.56E-07 6.92E-06 21 487 "MATN3,HOMEZ,APAF1,NOP14,PDE6B,BRI3BP,EIF2AK2,ZNF329,DTD2,MARVELD2,TBC1D19,ARSK,UTP15,SH3BP2,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5,ZDHHC20" MicroRNA hsa-miR-6893-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.99E-07 1.59E-03 7.69E-07 7.04E-06 25 665 "MATN3,HOMEZ,APAF1,NOP14,CDK18,CFL2,PIGR,UBXN2A,MPHOSPH8,EIF2AK2,SNX17,SLC35F6,DTD2,MARVELD2,TBC1D19,ARSK,ETF1,DLEU1,UTP15,SH3BP2,SLC30A6,GABRB1,GRSF1,PGAM5,LETM1" MicroRNA hsa-miR-1251:mirSVR_highEffct hsa-miR-1251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.02E-07 1.61E-03 7.76E-07 7.11E-06 19 405 "RGSL1,PDGFRA,GNPTAB,EPGN,NUDT12,SLC9C2,CLIP4,PACRGL,PIBF1,FMO1,PPARGC1A,BRD8,ARHGEF28,TEP1,RASSF6,ADAMTS19,STARD4,AXDND1,IFT88" MicroRNA hsa-miR-184:mirSVR_highEffct hsa-miR-184:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.18E-07 1.69E-03 8.17E-07 7.48E-06 14 221 "KIAA1211,CDKL2,PCK2,NGDN,PTPRC,RNASEL,TRAPPC12,TM9SF1,UFM1,GABRB1,CIDEB,TMEM183A,TBC1D1,FCRLA" MicroRNA hsa-miR-3184:mirSVR_highEffct hsa-miR-3184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.23E-07 1.72E-03 8.29E-07 7.59E-06 23 577 "MDM4,B4GALT3,NFATC4,SLC5A6,LINC02347,ODC1,CHIT1,CPNE6,SPATA18,G3BP2,TXNDC15,MARVELD2,FGFR3,TADA1,CGREF1,SLC22A4,TMEM183A,METAP2,STON1,AP4S1,PLB1,IRF1,LCP1" MicroRNA hsa-miR-6808-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.25E-07 1.73E-03 8.33E-07 7.63E-06 25 668 "MATN3,HOMEZ,APAF1,NOP14,CDK18,CFL2,PIGR,UBXN2A,MPHOSPH8,EIF2AK2,SNX17,SLC35F6,DTD2,MARVELD2,TBC1D19,ARSK,ETF1,DLEU1,UTP15,SH3BP2,SLC30A6,GABRB1,GRSF1,PGAM5,LETM1" MicroRNA hsa-miR-662:mirSVR_lowEffct hsa-miR-662:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.25E-07 1.73E-03 8.35E-07 7.65E-06 20 448 "FAM193A,BCL2L2,CD84,NRL,PDE6B,COPA,NOS1AP,RABGAP1L,GNPDA2,SUPT7L,RGS12,GRTP1,BORA,ETF1,FLT1,IVNS1ABP,COMMD6,LPIN1,TPO,ZNF84" MicroRNA hsa-miR-99b*:mirSVR_highEffct hsa-miR-99b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.34E-07 1.78E-03 8.57E-07 7.85E-06 11 130 "MYBPC1,CD84,ARHGEF7,ZNF664,ATAD2B,MPHOSPH8,FAM129A,ETF1,IKBIP,TMPO,AXDND1" MicroRNA hsa-miR-15a-5p:Functional MTI Functional MTI miRTarbase 3.45E-07 1.84E-03 8.85E-07 8.10E-06 26 717 "ABL2,TBC1D14,MCFD2,MSH2,ODC1,CDK17,PDE4D,GPR180,TM9SF2,SNX6,NCOR2,SREK1,TMEM161B,CLIP4,LRPPRC,RNASEL,SBNO1,TRIM28,FOXO1,IVNS1ABP,CENPJ,PPIP5K2,COP1,HSP90B1,TADA2B,SELENOI" MicroRNA hsa-miR-520f-3p:TargetScan hsa-miR-520f-3p TargetScan 3.47E-07 1.84E-03 8.88E-07 8.13E-06 21 492 "ADD1,APBB2,ATP2B4,ARHGEF7,NOVA1,FAM177A1,CFL2,LYSMD3,CLOCK,RNF219,CLIP4,NTN4,MBNL2,DNAJC27,IRF9,POLK,FLT1,BAZ1A,FZD10,ARHGAP30,IL6ST" MicroRNA hsa-miR-302c-3p.2:TargetScan hsa-miR-302c-3p.2 TargetScan 3.47E-07 1.84E-03 8.88E-07 8.13E-06 21 492 "ADD1,APBB2,ATP2B4,ARHGEF7,NOVA1,FAM177A1,CFL2,LYSMD3,CLOCK,RNF219,CLIP4,NTN4,MBNL2,DNAJC27,IRF9,POLK,FLT1,BAZ1A,FZD10,ARHGAP30,IL6ST" MicroRNA hsa-miR-136:PITA hsa-miR-136:PITA_TOP PITA 3.48E-07 1.85E-03 8.92E-07 8.17E-06 15 257 "SFTA3,APAF1,NOVA1,MPZL1,STRN3,TMEM161B,RGS4,TMEM33,CLIP4,MBNL2,ETF1,MEGF10,PPARGC1A,ADGRL3,GRSF1" MicroRNA hsa-miR-371-3p:mirSVR_lowEffct hsa-miR-371-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-07 1.86E-03 8.93E-07 8.18E-06 20 450 "KIAA1211,WDR19,PCDH9,MPC2,FCRL5,ZNF586,SNX17,PIGG,OCIAD1,BORA,MAEA,NDUFAF7,PEAR1,FLT1,NBEA,UHRF1BP1L,DRC1,TFDP1,LINC01551,SELENOI" MicroRNA hsa-miR-4279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.58E-07 1.91E-03 9.17E-07 8.39E-06 21 493 "ABL2,SLC4A4,RILPL1,THAP6,CEP135,G3BP2,RABGAP1L,ZNF329,TBC1D19,ATP6AP1L,FCAR,VEZT,DDX51,BRMS1L,UGGT2,UHRF1BP1L,PCDH17,SPIC,GPN1,TXK,FAM151B" MicroRNA hsa-miR-367-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.60E-07 1.91E-03 9.20E-07 8.42E-06 17 331 "MAP1B,CAD,CCNB1,F11R,SUPT7L,FAM129A,TMEM33,TXNDC15,RNF4,PCBD2,FNIP1,G2E3,GOLGA3,GUF1,IL6ST,FAM49A,LETM1" MicroRNA hsa-miR-422a:PITA hsa-miR-422a:PITA_TOP PITA 3.61E-07 1.92E-03 9.22E-07 8.45E-06 11 131 "ATP2B4,BCL2L2,XPR1,PDE4D,ZNF595,CLOCK,FOXG1,FOXO1,ANO4,GRSF1,KIF2A" MicroRNA hsa-miR-378:PITA hsa-miR-378:PITA_TOP PITA 3.61E-07 1.92E-03 9.22E-07 8.45E-06 11 131 "ATP2B4,BCL2L2,XPR1,PDE4D,ZNF595,CLOCK,FOXG1,FOXO1,ANO4,GRSF1,KIF2A" MicroRNA hsa-miR-542-3p:PITA hsa-miR-542-3p:PITA_TOP PITA 3.69E-07 1.96E-03 9.42E-07 8.62E-06 13 191 "MAP1B,ARHGAP5,SLC4A4,NOVA1,HECTD1,STRN3,CLIP4,SLC12A2,PCDH17,DOCK9,GRSF1,ADAMTS19,KLF12" MicroRNA hsa-miR-1909*:mirSVR_highEffct hsa-miR-1909*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.83E-07 2.04E-03 9.78E-07 8.96E-06 16 295 "APC,ARL1,PCCA,RCBTB2,PM20D1,SNX17,ATG10,MARVELD2,GMPR2,PEAR1,RUBCNL,NUBPL,SCYL2,RAPGEF6,SULT1E1,ADGRL3" MicroRNA hsa-miR-521:mirSVR_lowEffct hsa-miR-521:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.93E-07 2.09E-03 1.00E-06 9.18E-06 18 372 "ARL1,ATP2B4,TM9SF2,SNX6,ADGRF3,AKAP6,SNCAIP,SPATA18,WDR1,SPON2,VEZT,SLC12A2,GJB6,ACSL6,AP4S1,RAB2B,ADAMTS19,IL6ST" MicroRNA hsa-miR-5089-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.93E-07 2.09E-03 1.00E-06 9.18E-06 18 372 "BCL2L2,THAP6,CLOCK,C12orf65,CEP135,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,RB1,SBNO1,N4BP2L2,ZNF446,TMED2,GTF2H3,TXK,SELENOI,PABPN1" MicroRNA "TAGCTTT,MIR-9:MSigDB" "TAGCTTT,MIR-9:MSigDB" MSigDB 3.95E-07 2.10E-03 1.01E-06 9.22E-06 14 225 "PITPNM2,ARHGAP5,ZNF664,CDK17,CFL2,STRN3,KLHL3,ETF1,PDS5B,ERBIN,ATP11A,UBE2K,DCP2,KCNN2" MicroRNA hsa-miR-4271:mirSVR_highEffct hsa-miR-4271:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-07 2.12E-03 1.02E-06 9.30E-06 33 1071 "B4GALT3,NOVA1,TAF1B,CD1E,CDK18,RGSL1,PFKFB2,PM20D1,THTPA,PREPL,SNCAIP,COCH,TBC1D4,TSEN15,NR1I3,DTD2,LRPPRC,FAM172A,CWC27,ARL6IP4,GORAB,POLK,VEZT,TM9SF1,TADA1,NR5A2,CIDEB,KIF21B,JPH4,NFASC,ZBTB37,KMT5A,EEF1AKMT1" MicroRNA hsa-miR-1973:mirSVR_lowEffct hsa-miR-1973:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.04E-07 2.15E-03 1.03E-06 9.41E-06 15 260 "IL17D,AACS,NCOA1,CADM3,CDK17,PDE6B,PTPRVP,FCRL5,MATR3,PCGF3,PCBD2,DDX51,ATP8A2,CRB1,KIF2A" MicroRNA hsa-let-7c:PITA hsa-let-7c:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-miR-431*:mirSVR_lowEffct hsa-miR-431*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "CUL4A,NOP14,CENPBD1P1,BCL2L2,PIK3C2B,RCHY1,SNCAIP,DHX9,RASA1,TXNDC15,FGF9,FTLP10,GABRA2,IQGAP2,MIMT1,ACTR6,LAD1,LMNB1" MicroRNA hsa-miR-98:PITA hsa-miR-98:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7f:PITA hsa-let-7f:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7d:PITA hsa-let-7d:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7e:PITA hsa-let-7e:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7i:PITA hsa-let-7i:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7a:PITA hsa-let-7a:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7g:PITA hsa-let-7g:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-let-7b:PITA hsa-let-7b:PITA_TOP PITA 4.09E-07 2.17E-03 1.04E-06 9.48E-06 18 373 "ABL2,ZNF784,NCOA1,SLC4A4,NOVA1,SNX6,ATAD2B,AKAP6,GNPTAB,CEP135,ZFYVE16,CEP120,PCGF3,FNIP1,KIF21B,ACSL6,IGF1,SPRYD7" MicroRNA hsa-miR-365*:mirSVR_highEffct hsa-miR-365*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-07 2.21E-03 1.05E-06 9.62E-06 20 455 "COG6,HOMEZ,ARHGAP5,FAM193A,MPZL1,SLC5A8,ZNF664,RGSL1,PDGFRA,LINC01085,BOD1L1,DCAF8,ZFYVE16,SPATA18,NUDT12,CEP120,CWC27,SRP72,GOLGA3,GPR18" MicroRNA hsa-miR-1229:PITA hsa-miR-1229:PITA_TOP PITA 4.16E-07 2.21E-03 1.05E-06 9.63E-06 10 106 "MAP1B,APC,ASCL1,CADM3,PDE4D,PDGFRA,DNM3,SLC12A2,TMED2,KLF12" MicroRNA hsa-miR-4775:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-07 2.23E-03 1.06E-06 9.72E-06 16 297 "UHMK1,SMIM14,POU2F1,EPGN,DMXL1,SLC35F6,TMEM33,SLC8A1,LILRB1,PPARGC1A,SPIC,KLF12,NSD2,KCNT2,SELENOI,ZDHHC20" MicroRNA hsa-miR-511-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-07 2.26E-03 1.07E-06 9.82E-06 15 261 "RGS5,FAM177A1,CFL2,DCAF8,CLIP4,MBNL2,PCGF3,FNIP1,ZNF544,NT5C1B,TECRL,TADA2B,ZFHX2,IL6ST,NT5C1B-RDH14" MicroRNA hsa-miR-1539:mirSVR_lowEffct hsa-miR-1539:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.25E-07 2.26E-03 1.07E-06 9.83E-06 18 374 "MDM4,CUL4A,ADCY4,MSH2,ATP4B,CBLN3,UHMK1,PDGFRA,POU2F1,NCOR2,RNF31,MPHOSPH9,SH3BP2,GABRB1,TCF7,LINC01551,PLB1,EP400P1" MicroRNA hsa-miR-616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-07 2.35E-03 1.12E-06 1.02E-05 18 375 "TMEM132B,ATP7B,NRXN1,PKP1,GNPTAB,HEATR5A,RABGAP1L,MTX3,DCUN1D2,DLEU1,PAICS,ZNF446,OXGR1,UTP20,GOLGA3,COX18,TMPO,RIMBP2" MicroRNA hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 4.44E-07 2.36E-03 1.12E-06 1.03E-05 20 457 "MAP1B,EP400,ATP7B,ZNF664,FAM177A1,CHD1,PTGS2,SACS,RABGAP1L,RASA1,RB1,ETF1,FGF9,FBXO11,ADAM17,METAP2,KMT5A,TDG,MSH6,IGF1" MicroRNA hsa-miR-548m:PITA hsa-miR-548m:PITA_TOP PITA 4.44E-07 2.36E-03 1.12E-06 1.03E-05 20 457 "APAF1,NOVA1,XPR1,SNX6,ATAD2B,DMXL1,LATS2,CLIP1,LRRN2,TNFRSF19,FGFR3,SUCO,CCDC88A,PCDH17,GOLGA3,ANO4,DCP2,TDRD3,FAM49A,KIF2A" MicroRNA hsa-miR-18a-5p:Functional MTI Functional MTI miRTarbase 4.45E-07 2.37E-03 1.12E-06 1.03E-05 15 262 "CUL4A,CAD,PCDH9,PDE4D,DCAF8,MATR3,KLHL3,SUPT7L,TXNDC15,RNF4,FCGR2B,NBEA,ACIN1,CRB1,UBC" MicroRNA "GCATTTG,MIR-105:MSigDB" "GCATTTG,MIR-105:MSigDB" MSigDB 4.47E-07 2.38E-03 1.13E-06 1.03E-05 12 163 "MAP1B,NCOA1,ARHGEF7,PCCA,TM9SF2,NRXN1,PRKD1,NBEA,KLF12,HTR2A,IGF1,SPTSSA" MicroRNA hsa-miR-744:mirSVR_lowEffct hsa-miR-744:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.71E-07 2.51E-03 1.19E-06 1.09E-05 26 729 "PITPNM2,SNX24,ZNF784,AACS,KCTD12,CADM3,FGFRL1,SLC5A6,CCNA1,CACNA1E,WDFY2,PIK3C2B,C14orf119,FAM129A,SAP18,MAEA,PCGF3,TOMM40L,SPON2,SLC34A2,IVNS1ABP,LRCH1,AP4S1,ZFHX2,PLB1,LAD1" MicroRNA hsa-miR-125b-1*:mirSVR_lowEffct hsa-miR-125b-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.77E-07 2.54E-03 1.20E-06 1.10E-05 18 377 "MSH2,ASCL1,SLC4A4,SCARB1,ITGBL1,SMIM14,CEP120,RABGAP1L,DNMT3A,FAM129A,POLR1D,PACRGL,COMMD6,LINC01551,ZNF84,GALP,LHX9,LETM1" MicroRNA hsa-miR-185-5p:TargetScan hsa-miR-185-5p TargetScan 4.90E-07 2.61E-03 1.23E-06 1.13E-05 15 264 "MDM4,HOMEZ,PPP1R3E,BCL2L2,SCARB1,NUP37,KLHL3,PARPBP,FAM114A1,NMNAT2,HSPH1,PPIP5K2,CNTN2,GPR12,KIF3C" MicroRNA hsa-miR-4713-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.96E-07 2.64E-03 1.25E-06 1.14E-05 13 196 "NLN,CAMK4,XPR1,PIGR,THAP6,POU2F1,DLEU1,RAPGEF6,MRPS27,ACSL6,TEP1,AP4S1,PABPN1" MicroRNA hsa-miR-592:PITA hsa-miR-592:PITA_TOP PITA 4.96E-07 2.64E-03 1.25E-06 1.14E-05 13 196 "NOVA1,PCDH9,PDE4D,BOD1L1,HOMER1,AKAP6,G3BP2,SLC8A1,KDM3B,PCDH17,ADGRL3,ACSL6,KCNT2" MicroRNA hsa-miR-583:PITA hsa-miR-583:PITA_TOP PITA 4.96E-07 2.64E-03 1.25E-06 1.14E-05 18 378 "BIRC6,APC,SLC4A4,CACNA1E,FCHO2,LRRTM2,ZFYVE16,CEP350,G3BP2,ELK3,USP44,NBEA,SLC12A2,PKD2L2,KIF21B,NPAS3,ERBIN,XPO4" MicroRNA "GTGCCAT,MIR-183:MSigDB" "GTGCCAT,MIR-183:MSigDB" MSigDB 5.09E-07 2.71E-03 1.28E-06 1.17E-05 12 165 "FCHO2,PDE4D,CFL2,CSNK1G3,KLHL3,SACS,FOXO1,BRMS1L,YPEL5,EML4,TMPO,RIMBP2" MicroRNA hsa-miR-6511a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.12E-07 2.72E-03 1.29E-06 1.18E-05 21 504 "CCNB1,UHMK1,PDGFRA,PIGR,UBXN2A,MPHOSPH8,SNX17,SUPT7L,SLC35F6,TMEM33,TCTN2,FAM172A,ETF1,MRPS14,DCAF11,GABRB1,SNRNP35,COX18,ATP6V0A2,HSP90B1,GUF1" MicroRNA hsa-miR-770-5p:PITA hsa-miR-770-5p:PITA_TOP PITA 5.26E-07 2.80E-03 1.32E-06 1.21E-05 11 136 "ARHGAP5,STRN3,SACS,G3BP2,C12orf42,LATS2,MBNL2,NMNAT2,GTF3C2,BAZ1A,TMEM178A" MicroRNA hsa-miR-449a:TargetScan hsa-miR-449a TargetScan 5.30E-07 2.82E-03 1.33E-06 1.22E-05 22 549 "MDM4,PITPNM2,MCFD2,NCOA1,ATP1A2,CACNA1E,CAMK4,PDGFRA,CHD1,POU2F1,CLOCK,LRRTM2,PRKD1,NOS1AP,FOXG1,CCDC88A,DCAF11,GABRB1,CNTN2,GPR12,C12orf73,LHX9" MicroRNA hsa-miR-34c-5p:TargetScan hsa-miR-34c-5p TargetScan 5.30E-07 2.82E-03 1.33E-06 1.22E-05 22 549 "MDM4,PITPNM2,MCFD2,NCOA1,ATP1A2,CACNA1E,CAMK4,PDGFRA,CHD1,POU2F1,CLOCK,LRRTM2,PRKD1,NOS1AP,FOXG1,CCDC88A,DCAF11,GABRB1,CNTN2,GPR12,C12orf73,LHX9" MicroRNA hsa-miR-34a-5p:TargetScan hsa-miR-34a-5p TargetScan 5.30E-07 2.82E-03 1.33E-06 1.22E-05 22 549 "MDM4,PITPNM2,MCFD2,NCOA1,ATP1A2,CACNA1E,CAMK4,PDGFRA,CHD1,POU2F1,CLOCK,LRRTM2,PRKD1,NOS1AP,FOXG1,CCDC88A,DCAF11,GABRB1,CNTN2,GPR12,C12orf73,LHX9" MicroRNA hsa-miR-449b-5p:TargetScan hsa-miR-449b-5p TargetScan 5.30E-07 2.82E-03 1.33E-06 1.22E-05 22 549 "MDM4,PITPNM2,MCFD2,NCOA1,ATP1A2,CACNA1E,CAMK4,PDGFRA,CHD1,POU2F1,CLOCK,LRRTM2,PRKD1,NOS1AP,FOXG1,CCDC88A,DCAF11,GABRB1,CNTN2,GPR12,C12orf73,LHX9" MicroRNA hsa-miR-361-5p:PITA hsa-miR-361-5p:PITA_TOP PITA 5.39E-07 2.87E-03 1.35E-06 1.24E-05 15 266 "MAP1B,ANKRD34B,BTF3,PCDH9,HOMER1,SREK1,G3BP2,MTX3,ARGLU1,MBNL2,ELOVL7,MYT1L,UBE2K,IGF1,LAD1" MicroRNA hsa-miR-105*:mirSVR_lowEffct hsa-miR-105*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.46E-07 2.90E-03 1.37E-06 1.25E-05 21 506 "NLN,ARHGEF7,TAF1B,CAST,AMDHD1,FCGR2C,SNTG2,CHIT1,ZNF595,LINC01085,CSNK1G3,DMXL1,LOC439933,MBNL2,SNORA53,NPAS3,ADGRL3,ZMYM2,PGAM5,KCNN2,LOX" MicroRNA hsa-miR-99b*:mirSVR_lowEffct hsa-miR-99b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-07 2.92E-03 1.37E-06 1.26E-05 23 595 "COG6,HOMEZ,ATP2B4,RAB29,NOVA1,SMIM14,JAKMIP1,FAM163A,CEP135,PRKD1,NUDT12,ELOVL7,PIBF1,VEZT,HSPH1,NFASC,GC,MIMT1,DOCK9,TDG,ADAMTS19,IGF1,KIT" MicroRNA hsa-miR-363-3p:Functional MTI Functional MTI miRTarbase 5.67E-07 3.01E-03 1.42E-06 1.30E-05 17 342 "MAP1B,CAD,CCNB1,F11R,SUPT7L,FAM129A,TMEM33,TXNDC15,RNF4,PCBD2,FNIP1,G2E3,GOLGA3,GUF1,IL6ST,FAM49A,LETM1" MicroRNA hsa-miR-488-3p:TargetScan hsa-miR-488-3p TargetScan 6.23E-07 3.31E-03 1.56E-06 1.43E-05 16 306 "KIAA1211,APBB2,CDKL4,PPP1R12B,NGDN,KLHL3,FAM129A,RASA1,EFNA5,ELK3,FGFR3,CCDC88A,MTUS2,MSH6,IGF1,LOX" MicroRNA hsa-miR-603:PITA hsa-miR-603:PITA_TOP PITA 6.45E-07 3.43E-03 1.61E-06 1.48E-05 18 385 "ABL2,ATP2B4,CDKL2,HECTD1,CSNK1G3,MATR3,SREK1,CEP350,COCH,RGS4,POLR1D,MEGF10,PDS5B,ERBIN,PCDH17,PPARGC1A,XPO4,UBE2K" MicroRNA hsa-miR-4300:mirSVR_highEffct hsa-miR-4300:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.46E-07 3.43E-03 1.61E-06 1.48E-05 19 426 "PPFIA4,B4GALT3,FCGR2C,PDE4D,ITGBL1,COPA,DNMT3A,RASA1,RNASEL,DHRS2,FCGR2B,PEAR1,DDX51,WDCP,NMNAT2,NCSTN,TPTE2,LHX9,IFT88" MicroRNA hsa-miR-220a:mirSVR_lowEffct hsa-miR-220a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.51E-07 3.46E-03 1.62E-06 1.49E-05 23 601 "CD84,LDB2,PCDH9,PDE6B,ZNF595,ATAD2B,ADGRF3,THAP6,KLHL3,NUDT12,PARPBP,OGFOD2,CLIP4,CWC27,CLIP1,PCBD2,FGF9,POLK,SUCO,UGGT2,PDS5B,NLRP8,PAPPA2" MicroRNA hsa-miR-421:Functional MTI Functional MTI miRTarbase 6.66E-07 3.54E-03 1.66E-06 1.52E-05 14 235 "MCFD2,MYBPC1,COPA,TTC37,PSME1,REST,FAM172A,ZNF219,DNAJC27,TM9SF1,FBXO11,PPARGC1A,RAB2B,IGF1" MicroRNA hsa-miR-132*:mirSVR_lowEffct hsa-miR-132*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.69E-07 3.56E-03 1.67E-06 1.53E-05 19 427 "ACOX3,MYH6,CDK18,PDGFRA,WDFY2,CPNE6,PITX1,FAM53A,PIGG,TINF2,RNF31,TMEM33,SNRPF,ATP8A2,LILRB1,TBC1D1,PLB1,MFSD2B,LETM1" MicroRNA hsa-miR-378a-5p:Functional MTI Functional MTI miRTarbase 6.70E-07 3.56E-03 1.67E-06 1.53E-05 18 386 "ABL2,TMEM132B,NLN,ASTN1,PIGG,RABGAP1L,SLC35F6,DCUN1D2,DLEU1,TLR6,PCBD2,ZCCHC8,NUBPL,PAICS,PPARGC1A,DCP2,ZNF84,IRF1" MicroRNA hsa-miR-543:TargetScan hsa-miR-543 TargetScan 7.15E-07 3.80E-03 1.78E-06 1.63E-05 22 559 "BIRC6,KCTD12,DCLK1,PCSK1,PDE4D,GPR180,AKAP6,RCHY1,CLOCK,MATR3,EFR3B,PDS5B,KDM5B,IQGAP2,NPAS3,PPARGC1A,ATP11A,METAP2,GUF1,DCP2,LHX9,LCP1" MicroRNA hsa-miR-1225-5p:PITA hsa-miR-1225-5p:PITA_TOP PITA 7.19E-07 3.82E-03 1.79E-06 1.64E-05 9 87 "BCL2L2,MPZL1,KLHL3,RB1,FAM172A,MEGF10,IQGAP2,PSME4,ZMYM2" MicroRNA hsa-miR-525-3p:mirSVR_lowEffct hsa-miR-525-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.42E-07 3.95E-03 1.85E-06 1.69E-05 19 430 "PITPNM2,NRL,SCARB1,CDK18,THTPA,EPGN,COCH,RASA1,FAM228A,TOMM40L,SUCO,ZNF274,SRP72,EML4,TFDP1,ZBTB49,TRPC4,TADA2B,IRF1" MicroRNA hsa-miR-129-5p:TargetScan hsa-miR-129-5p TargetScan 7.46E-07 3.97E-03 1.86E-06 1.70E-05 21 516 "APC,NCOA1,ATP2B4,CAMK4,CAST,FCHO2,NRXN1,HOMER1,CLOCK,MATR3,DNMT3A,FAM129A,RASA1,CCDC88A,MYT1L,GABRB1,JPH4,PCDH17,MSH6,IL6ST,ANKS1B" MicroRNA hsa-miR-142-3p.1:TargetScan hsa-miR-142-3p.1 TargetScan 7.48E-07 3.98E-03 1.86E-06 1.70E-05 15 273 "ABL2,APC,ARL1,CD84,CFL2,EPN1,HECTD1,HEATR5A,CLOCK,PCGF3,FOXO1,FAM114A1,EML4,BAZ1A,IL6ST" MicroRNA hsa-miR-886-3p:mirSVR_lowEffct hsa-miR-886-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.58E-07 4.03E-03 1.88E-06 1.73E-05 20 473 "EP400,NOP14,CADM3,LINC02347,RILPL1,PDE6B,CCDC122,ITGBL1,PITX1,MPHOSPH8,SNX17,MBNL2,MARVELD2,ZNF219,NFASC,SLC7A8,ACTR6,TPO,ZBED3-AS1,AXDND1" MicroRNA hsa-miR-615-3p:mirSVR_lowEffct hsa-miR-615-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.71E-07 4.10E-03 1.92E-06 1.76E-05 16 311 "ASCL1,AACS,KCTD12,TAPT1,NCOR2,DCAF8,RNF219,PCGF3,LRRN2,FLT1,KIF21B,MAST4,GOLGA3,TPO,HTR2A,PLB1" MicroRNA hsa-miR-4260:mirSVR_highEffct hsa-miR-4260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.81E-07 4.15E-03 1.94E-06 1.78E-05 22 562 "MCC,AMDHD1,PDGFRA,COLEC11,ITGBL1,VCAN,EPS8L1,PTPRC,STX2,DLEU1,SLC22A17,POLK,FLT1,SGCG,YPEL5,IKBIP,TGM1,FCRL6,JCHAIN,LINC00272,KCNJ9,RMST" MicroRNA hsa-miR-518f:mirSVR_highEffct hsa-miR-518f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.15E-07 4.33E-03 2.02E-06 1.85E-05 14 239 "ZNF664,AKAP6,LOC439933,WDR1,DNMT3A,CLIP4,LATS2,DLEU1,GMPR2,USP44,GORAB,ZCCHC8,FBXO11,LPIN1" MicroRNA "TAATAAT,MIR-126:MSigDB" "TAATAAT,MIR-126:MSigDB" MSigDB 8.24E-07 4.38E-03 2.05E-06 1.87E-05 13 205 "MATN3,FGFRL1,BCL2L2,NOVA1,XPR1,ARGLU1,NR5A2,UHRF1BP1L,ERBIN,PPARGC1A,TMED2,TGFBI,KLF12" MicroRNA hsa-miR-450a-1-3p:Functional MTI Functional MTI miRTarbase 8.35E-07 4.44E-03 2.07E-06 1.90E-05 18 392 "MATN3,MDM4,MCFD2,PIGR,POU2F1,CLOCK,ZNF329,TMEM33,TBC1D19,ARSK,ZCCHC8,GOLGA3,COX18,UBC,IGF1,ZNF324B,FAM151B,ZDHHC20" MicroRNA hsa-miR-6513-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.35E-07 4.44E-03 2.07E-06 1.90E-05 18 392 "MATN3,MDM4,PIGR,CLOCK,BRI3BP,RB1,ZNF329,TMEM33,TBC1D19,ARSK,ZCCHC8,TMED2,GOLGA3,COX18,IGF1,ZNF324B,FAM151B,ZDHHC20" MicroRNA hsa-miR-1236:PITA hsa-miR-1236:PITA_TOP PITA 8.56E-07 4.55E-03 2.12E-06 1.94E-05 14 240 "MAP1B,STARD13,CACNA1E,NRXN1,SREK1,ARGLU1,TMEM161B,MAEA,SUCO,FBXO11,PCDH17,KLF12,NSD2,ZNF10" MicroRNA hsa-miR-3193:mirSVR_lowEffct hsa-miR-3193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.66E-07 4.61E-03 2.15E-06 1.97E-05 18 393 "RALGAPA1,MAP1B,COG6,NCOA1,CPNE6,SNX17,SETDB2,PACRGL,DLEU1,F10,FOXO1,NMNAT2,NFASC,METAP2,GPR12,NCSTN,PLB1,LETM1" MicroRNA hsa-miR-92a-2*:mirSVR_highEffct hsa-miR-92a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.25E-07 4.92E-03 2.29E-06 2.10E-05 27 805 "ADD1,HOMEZ,NOP14,ATP1A2,B4GALT3,CD84,ARHGEF7,CDK18,CFL2,THAP6,COPA,RNASE9,SNX17,PTPRH,DNMT3A,ZNF329,MBNL2,FCAR,MYT1L,NAAA,IQGAP2,PPIP5K2,ADAMTS19,PAPPA2,STARD4,MZF1,ANKS1B" MicroRNA hsa-miR-551b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-07 4.95E-03 2.30E-06 2.11E-05 11 144 "COG6,KCTD12,GPR180,PIK3C2B,BRI3BP,ITSN2,MTX3,PPIP5K2,EML4,TXK,ZBTB41" MicroRNA hsa-miR-1269:PITA hsa-miR-1269:PITA_TOP PITA 9.61E-07 5.11E-03 2.38E-06 2.18E-05 10 116 "ATP2B4,PDE4D,ZNF595,CLOCK,FOXO1,FBXO11,PCDH17,ANO4,GRSF1,RIMBP2" MicroRNA "AGCACTT,MIR-526B:MSigDB" "AGCACTT,MIR-526B:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-520D:MSigDB" "AGCACTT,MIR-520D:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-520C:MSigDB" "AGCACTT,MIR-520C:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-302A:MSigDB" "AGCACTT,MIR-302A:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-520A:MSigDB" "AGCACTT,MIR-520A:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-93:MSigDB" "AGCACTT,MIR-93:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-372:MSigDB" "AGCACTT,MIR-372:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-373:MSigDB" "AGCACTT,MIR-373:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-302B:MSigDB" "AGCACTT,MIR-302B:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-520E:MSigDB" "AGCACTT,MIR-520E:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-520B:MSigDB" "AGCACTT,MIR-520B:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-302D:MSigDB" "AGCACTT,MIR-302D:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA "AGCACTT,MIR-302C:MSigDB" "AGCACTT,MIR-302C:MSigDB" MSigDB 9.91E-07 5.27E-03 2.44E-06 2.23E-05 16 317 "ULK1,CFL2,KLHL3,NTN4,LATS2,MBNL2,DNAJC27,SUCO,SDC1,FLT1,FBXO11,BRMS1L,MYT1L,NPAS3,KLF12,ZBTB41" MicroRNA hsa-miR-652:mirSVR_lowEffct hsa-miR-652:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-06 5.49E-03 2.54E-06 2.32E-05 16 318 "MATN3,ZNF595,POU2F1,NCOR2,SACS,MARVELD2,EFS,TM9SF1,MYO16,KIF21B,MCCC2,ZBTB37,NT5C1B,SLAIN1,C12orf73,ZMYM2" MicroRNA hsa-miR-380:PITA hsa-miR-380:PITA_TOP PITA 1.04E-06 5.52E-03 2.55E-06 2.33E-05 18 398 "MAP1B,BIRC6,ARHGAP5,SLC4A4,NRXN1,LYSMD3,ZFYVE16,TMEM33,DCUN1D2,CCDC88A,KDM3B,PCDH17,STON1,XPO4,ADAMTS19,HMGCR,SLAIN1,KIF2A" MicroRNA hsa-miR-539-5p:Functional MTI Functional MTI miRTarbase 1.08E-06 5.75E-03 2.65E-06 2.43E-05 13 210 "TAF1B,COPA,POU2F1,COCH,SLC35F6,WDR1,DNMT3A,REST,IKBIP,STRN,ACSL6,IGF1,C12orf73" MicroRNA hsa-miR-181a*:mirSVR_highEffct hsa-miR-181a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-06 6.07E-03 2.80E-06 2.57E-05 11 147 "KCTD12,CFL2,PACRGL,CWC27,ABCA11P,UGGT2,TDG,TNR,GPN1,ZMYM2,KCNN2" MicroRNA hsa-miR-138-5p:TargetScan hsa-miR-138-5p TargetScan 1.15E-06 6.11E-03 2.82E-06 2.58E-05 20 486 "PPFIA4,NCOA1,NOVA1,CLOCK,FAM169A,PIGG,DNMT3A,ARGLU1,PCGF3,CLIP1,NBEA,SCYL2,ARHGEF40,LIMCH1,GABRB1,KIF21B,PPARGC1A,MTUS2,MSH6,KLF12" MicroRNA hsa-miR-668:mirSVR_highEffct hsa-miR-668:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-06 6.34E-03 2.92E-06 2.68E-05 19 444 "ADD1,SNX24,LINC02347,CAST,PCDH9,RGSL1,RCBTB2,PGGT1B,COPA,LRRTM2,ARGLU1,RNASEL,SNORA49,VEZT,ERAP1,IKBIP,NPFFR2,METAP2,ZNF140" MicroRNA hsa-miR-663:mirSVR_lowEffct hsa-miR-663:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-06 6.35E-03 2.93E-06 2.68E-05 27 816 "ADORA1,RGS5,NOP14,AACS,SLC5A6,CACNA1E,PDGFRA,THTPA,NCOR2,KIAA0040,WDR1,C14orf119,GUSBP3,MARVELD2,ZNF219,SAP18,MAEA,CLIP1,TACC3,FLT1,SLC34A2,KIF21B,NAAA,SLC7A8,ZFHX2,KIR2DS4,AXDND1" MicroRNA hsa-miR-5590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-06 6.39E-03 2.94E-06 2.69E-05 13 212 "ULK1,SNX24,CDKL2,UHMK1,PDE4D,UBXN2A,CEP120,EGLN3,REST,EFNA5,SPIC,MSH6,ZNF324B" MicroRNA "TTTTGAG,MIR-373:MSigDB" "TTTTGAG,MIR-373:MSigDB" MSigDB 1.20E-06 6.39E-03 2.94E-06 2.69E-05 13 212 "PITPNM2,ARHGAP5,SLC4A4,ATP2B4,KCTD12,CAMK4,CFL2,MBNL2,SCYL2,NMNAT2,PPARGC1A,BAZ1A,PABPN1" MicroRNA hsa-miR-622:PITA hsa-miR-622:PITA_TOP PITA 1.20E-06 6.40E-03 2.95E-06 2.70E-05 14 247 "MPHOSPH8,RASA1,RB1,USP44,GOLGA2P5,CCDC88A,MEGF10,PCDH17,PSME4,KHNYN,GRSF1,RIMBP2,ATP6V0A2,UBE2K" MicroRNA hsa-miR-137:Non-Functional MTI Non-Functional MTI miRTarbase 1.22E-06 6.49E-03 2.99E-06 2.73E-05 11 148 "CUL4A,DCLK1,PTGS2,SUPT7L,RNF4,FNIP1,LIMCH1,KDM5B,GOLGA3,KLF12,KIT" MicroRNA hsa-miR-1274a:PITA hsa-miR-1274a:PITA_TOP PITA 1.22E-06 6.49E-03 2.99E-06 2.73E-05 11 148 "NOVA1,CHD1,NRXN1,CSNK1G3,G3BP2,ALKAL2,MYT1L,KDM3B,PCDH17,KCNN2,PABPN1" MicroRNA hsa-miR-551a:mirSVR_lowEffct hsa-miR-551a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-06 6.51E-03 2.99E-06 2.74E-05 15 284 "ADGRD1,ITGBL1,TAPT1,SPATA18,NR1H4,DNMT3A,RNF31,EIF2B1,ETF1,ABCA11P,N4BP2L2,TADA1,PUS1,RNF17,YTHDC2" MicroRNA hsa-miR-943:mirSVR_highEffct hsa-miR-943:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-06 6.69E-03 3.07E-06 2.81E-05 25 720 "SNX24,BLZF1,ARL1,ASCL1,NOVA1,CAD,SCARB1,CFL2,C12orf65,RASA1,PACRGL,KLHL12,TBC1D19,MAEA,KDM3B,SRP72,DRC1,CRB1,GTF3C2,TMPO,MAEL,ADAMTS19,MZF1,ZMYM2,TDRD3" MicroRNA hsa-miR-127-5p:PITA hsa-miR-127-5p:PITA_TOP PITA 1.26E-06 6.72E-03 3.08E-06 2.82E-05 14 248 "ATP2B4,CADM3,PRKD1,OCIAD1,G3BP2,RB1,ARGLU1,MBNL2,SLC8A1,PKD2L2,PCDH17,PPARGC1A,TCF7,RAB2B" MicroRNA hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-06 6.73E-03 3.09E-06 2.83E-05 16 323 "NLN,COG6,ASCL1,PPP1R3E,CD84,SMIM14,LRRTM2,ATG10,KLHL12,ATP6AP1L,FGF9,PLEKHA6,LIMCH1,PCDH17,STRN,LHX9" MicroRNA hsa-miR-22-3p:TargetScan hsa-miR-22-3p TargetScan 1.27E-06 6.78E-03 3.11E-06 2.85E-05 19 446 "APBB2,ASCL1,NCOA1,CADM3,LTB4R,HOMER1,DNM3,KIAA0040,NOP9,DNMT3A,PACRGL,DNAJC27,LRRN2,PLEKHA6,N4BP2,NPAS3,LRCH1,KHNYN,GPR161" MicroRNA hsa-miR-3666:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-06 7.07E-03 3.24E-06 2.97E-05 17 364 "MCC,STARD13,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,ERBIN,GRSF1,GPR161,UBC,TENT2,IRF1,LMLN" MicroRNA hsa-miR-1228:PITA hsa-miR-1228:PITA_TOP PITA 1.36E-06 7.23E-03 3.32E-06 3.04E-05 12 181 "CAMK4,NRXN1,ATAD2B,C1orf116,CLOCK,CSNK1G3,FOXG1,SLC30A6,MYT1L,ATP8A2,NPAS3,KHNYN" MicroRNA hsa-miR-488:PITA hsa-miR-488:PITA_TOP PITA 1.43E-06 7.59E-03 3.48E-06 3.18E-05 16 326 "MAP1B,PPP1R12B,NFXL1,PRKD1,BIVM,KLHL3,RASA1,FGFR3,CCDC88A,MYT1L,PDS5B,ERBIN,UBC,IGF1,SPTSSA,PABPN1" MicroRNA hsa-miR-4295:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-06 7.62E-03 3.49E-06 3.20E-05 17 366 "MCC,STARD13,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,ERBIN,GRSF1,GPR161,UBC,TENT2,IRF1,LMLN" MicroRNA hsa-miR-518d-3p:mirSVR_highEffct hsa-miR-518d-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-06 7.67E-03 3.51E-06 3.21E-05 12 182 "ARHGEF7,CD1E,ZNF664,LOC439933,WDR1,DNMT3A,CLIP4,DLEU1,GORAB,ZCCHC8,FBXO11,LPIN1" MicroRNA hsa-miR-324-3p:mirSVR_highEffct hsa-miR-324-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-06 7.69E-03 3.52E-06 3.22E-05 21 538 "HOMEZ,ARHGEF7,PIK3C2B,TAPT1,ZNF586,DCAF8,RABGAP1L,EGLN3,RGS4,BORA,SAP18,PCGF3,TOMM40L,FOXO1,CGREF1,LPIN1,C5orf56,AP4S1,RMST,FAM71C,SKA3" MicroRNA "GTGCAAT,MIR-25:MSigDB" "GTGCAAT,MIR-25:MSigDB" MSigDB 1.52E-06 8.08E-03 3.69E-06 3.38E-05 15 289 "NOVA1,FCHO2,DMXL1,LATS2,RNF4,PCGF3,USP44,POLK,FOXG1,BRMS1L,PLEKHA6,PDS5B,IQGAP2,DOCK9,FZD10" MicroRNA "GTGCAAT,MIR-367:MSigDB" "GTGCAAT,MIR-367:MSigDB" MSigDB 1.52E-06 8.08E-03 3.69E-06 3.38E-05 15 289 "NOVA1,FCHO2,DMXL1,LATS2,RNF4,PCGF3,USP44,POLK,FOXG1,BRMS1L,PLEKHA6,PDS5B,IQGAP2,DOCK9,FZD10" MicroRNA "GTGCAAT,MIR-32:MSigDB" "GTGCAAT,MIR-32:MSigDB" MSigDB 1.52E-06 8.08E-03 3.69E-06 3.38E-05 15 289 "NOVA1,FCHO2,DMXL1,LATS2,RNF4,PCGF3,USP44,POLK,FOXG1,BRMS1L,PLEKHA6,PDS5B,IQGAP2,DOCK9,FZD10" MicroRNA "GTGCAAT,MIR-363:MSigDB" "GTGCAAT,MIR-363:MSigDB" MSigDB 1.52E-06 8.08E-03 3.69E-06 3.38E-05 15 289 "NOVA1,FCHO2,DMXL1,LATS2,RNF4,PCGF3,USP44,POLK,FOXG1,BRMS1L,PLEKHA6,PDS5B,IQGAP2,DOCK9,FZD10" MicroRNA "GTGCAAT,MIR-92:MSigDB" "GTGCAAT,MIR-92:MSigDB" MSigDB 1.52E-06 8.08E-03 3.69E-06 3.38E-05 15 289 "NOVA1,FCHO2,DMXL1,LATS2,RNF4,PCGF3,USP44,POLK,FOXG1,BRMS1L,PLEKHA6,PDS5B,IQGAP2,DOCK9,FZD10" MicroRNA hsa-miR-197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-06 8.11E-03 3.70E-06 3.39E-05 18 409 "ZNF784,ATP1A2,NRL,MORN2,CPNE6,AKAP6,HEATR5A,NGDN,DMXL1,RAN,SH3BP2,NUBPL,CENPJ,ZNF274,STRN,ATP11A,GTF2H3,ZNF324B" MicroRNA hsa-miR-372-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-06 8.21E-03 3.75E-06 3.43E-05 16 328 "TMEM132B,UHMK1,PKP1,GNPTAB,HEATR5A,RABGAP1L,DCUN1D2,DLEU1,PAICS,ZNF446,OXGR1,UTP20,GOLGA3,COX18,TMPO,RIMBP2" MicroRNA hsa-miR-338-3p:PITA hsa-miR-338-3p:PITA_TOP PITA 1.56E-06 8.29E-03 3.78E-06 3.46E-05 13 217 "TMEM132B,SEMA6A,NOVA1,NRL,G3BP2,ARGLU1,FGF9,MYT1L,ADAM17,EML4,TFDP1,ZNF470,ZMYM2" MicroRNA hsa-miR-3663-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-06 8.29E-03 3.78E-06 3.46E-05 13 217 "ABL2,TMEM132B,HEATR5A,CSNK1G3,RABGAP1L,SBNO1,DCUN1D2,ARSK,TLR6,PCBD2,ZCCHC8,NUBPL,ZNF446" MicroRNA hsa-miR-512-5p:PITA hsa-miR-512-5p:PITA_TOP PITA 1.59E-06 8.44E-03 3.85E-06 3.52E-05 11 152 "MAP1B,PPP1R12B,BCL2L2,PCSK1,HOMER1,LRRTM2,CEP350,MTX3,PARPBP,PCDH17,TFDP1" MicroRNA hsa-miR-505-3p.1:TargetScan hsa-miR-505-3p.1 TargetScan 1.64E-06 8.72E-03 3.97E-06 3.63E-05 13 218 "ABL2,APBB2,ATP12A,NOVA1,CACNA1E,C1orf116,ELK3,MYT1L,GABRB1,ATP8A2,GTF3C2,IL6ST,KIT" MicroRNA hsa-miR-1:PITA hsa-miR-1:PITA_TOP PITA 1.72E-06 9.15E-03 4.16E-06 3.81E-05 17 371 "RALGAPA1,ABL2,SMIM14,MATR3,GNPDA2,WDR1,RASA1,NBEA,PCDH17,ADGRA3,ANO4,HSP90B1,IGF1,LHX9,TMEM178A,KIF2A,KIF3C" MicroRNA hsa-miR-206:PITA hsa-miR-206:PITA_TOP PITA 1.72E-06 9.15E-03 4.16E-06 3.81E-05 17 371 "RALGAPA1,ABL2,SMIM14,MATR3,GNPDA2,WDR1,RASA1,NBEA,PCDH17,ADGRA3,ANO4,HSP90B1,IGF1,LHX9,TMEM178A,KIF2A,KIF3C" MicroRNA hsa-miR-375:TargetScan hsa-miR-375 TargetScan 1.73E-06 9.17E-03 4.17E-06 3.82E-05 13 219 "ASCL1,CAST,PDE4D,LYSMD3,PRKD1,MATR3,KLHL3,NBEA,NR5A2,HSPH1,KLF12,LHX9,LMLN" MicroRNA hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 1.75E-06 9.32E-03 4.23E-06 3.88E-05 14 255 "MAP1B,CCNB1,UBXN2A,PTGS2,RASA1,RB1,POLK,FOXO1,EML4,CCDC169,KCNJ9,KIR3DL1,KIR3DL2,LIG4" MicroRNA "ACACTAC,MIR-142-3P:MSigDB" "ACACTAC,MIR-142-3P:MSigDB" MSigDB 1.77E-06 9.42E-03 4.28E-06 3.92E-05 10 124 "APC,CFL2,HECTD1,STRN3,RNF31,PCGF3,SUCO,EML4,BAZ1A,ZBTB41" MicroRNA hsa-miR-483-3p.2:TargetScan hsa-miR-483-3p.2 TargetScan 1.77E-06 9.42E-03 4.28E-06 3.92E-05 10 124 "MDM4,PIWIL1,HOMER1,RCHY1,DCT,RAN,RNF4,KIF21B,ATP8A2,IGF1" MicroRNA hsa-miR-613:PITA hsa-miR-613:PITA_TOP PITA 1.79E-06 9.49E-03 4.31E-06 3.94E-05 17 372 "RALGAPA1,ABL2,SMIM14,MATR3,GNPDA2,WDR1,RASA1,NBEA,PCDH17,ADGRA3,ANO4,HSP90B1,IGF1,LHX9,TMEM178A,KIF2A,KIF3C" MicroRNA hsa-miR-4325:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-06 9.60E-03 4.35E-06 3.98E-05 11 154 "CCNB1,PDE4D,CLOCK,F11R,RB1,TMEM33,RNF4,ZNF256,PCBD2,ZNF84,LETM1" MicroRNA hsa-miR-4719:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-06 9.60E-03 4.35E-06 3.98E-05 11 154 "MAP1B,CDKL2,PDGFRA,NUDT12,OCIAD1,REST,CLIP4,SETDB2,PACRGL,FNIP1,SLC12A2" MicroRNA hsa-miR-455-5p:TargetScan hsa-miR-455-5p TargetScan 1.81E-06 9.63E-03 4.36E-06 3.99E-05 12 186 "CAST,PDGFRA,NRXN1,CLOCK,DMXL1,MEMO1,PLEKHA6,NPAS3,KDM3B,PPIP5K2,DOCK9,LHX9" MicroRNA hsa-miR-143:PITA hsa-miR-143:PITA_TOP PITA 1.82E-06 9.65E-03 4.37E-06 4.00E-05 13 220 "ABL2,MAP1B,TMEM132B,NFXL1,DCLK1,AKAP6,STRN3,CSNK1G3,DNMT3A,PSME4,KLF12,NSD2,NUAK2" MicroRNA hsa-miR-1910-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-06 9.69E-03 4.39E-06 4.02E-05 20 501 "CCNB1,UHMK1,PDGFRA,PIGR,UBXN2A,SNX17,SUPT7L,SLC35F6,TMEM33,TCTN2,FAM172A,ETF1,MRPS14,DCAF11,GABRB1,SNRNP35,COX18,ATP6V0A2,HSP90B1,GUF1" MicroRNA hsa-miR-455-3p:PITA hsa-miR-455-3p:PITA_TOP PITA 1.83E-06 9.75E-03 4.41E-06 4.04E-05 14 256 "SEMA6A,B4GALT3,NOVA1,PCDH9,SLC25A3,NRXN1,ATAD2B,PITX1,FGFR3,SLC8A1,SLC12A2,ACSL6,FZD10,LOX" MicroRNA hsa-miR-498:PITA hsa-miR-498:PITA_TOP PITA 1.83E-06 9.75E-03 4.41E-06 4.04E-05 14 256 "MATN3,MCC,NCOA1,ODC1,CHD1,ATAD2B,BIVM,SREK1,TMEM33,EML4,RIMBP2,KLF12,SPTSSA,ZBTB41" MicroRNA hsa-miR-4256:mirSVR_highEffct hsa-miR-4256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-06 9.97E-03 4.51E-06 4.13E-05 21 547 "ATP1A2,AP1G2,PNP,ZMYM5,RGSL1,CFL2,THAP6,HEATR5A,NGDN,RASA1,RB1,CLIP4,PIBF1,PAICS,SLC15A4,GABRA2,KIF21B,INSM2,ADAMTS19,CCDC169,IFT88" MicroRNA hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA_TOP PITA 1.88E-06 9.99E-03 4.51E-06 4.13E-05 15 294 "BIRC6,DCLK1,AKAP6,CSNK1G3,MATR3,CLIP4,SLC12A2,NR5A2,PPARGC1A,STON1,EML4,MSH6,RIMBP2,KLF12,IGF1" MicroRNA "ATGTACA,MIR-493:MSigDB" "ATGTACA,MIR-493:MSigDB" MSigDB 1.88E-06 9.99E-03 4.51E-06 4.13E-05 15 294 "MAP1B,ANKRD34B,ARHGAP5,NCOA1,PDE4D,ITSN2,TBC1D4,MBNL2,ETF1,FOXO1,NBEA,KDM5B,ADGRL3,ANO4,DOCK9" MicroRNA hsa-miR-1911*:mirSVR_highEffct hsa-miR-1911*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.88E-06 9.99E-03 4.51E-06 4.13E-05 19 458 "MDM4,COG6,MSH2,CFAP54,PRKD1,RGS4,DRAM1,TMEM156,TOMM40L,NUBPL,DCAF11,CD244,ERBIN,GPR12,NT5C1B,ZMYM2,RILPL2,PABPN1,LOX" MicroRNA hsa-let-7i*:mirSVR_highEffct hsa-let-7i*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.92E-06 1.02E-02 4.62E-06 4.23E-05 11 155 "SEMA6A,KCTD12,SNTG2,ZMYM5,PIK3C2B,SPATA18,ADGRV1,FOXG1,MBIP,HSPH1,HTR2A" MicroRNA hsa-miR-5589-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-06 1.04E-02 4.68E-06 4.29E-05 16 334 "ULK1,PPFIA4,BCL2L2,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,SBNO1,ARSK,N4BP2L2,ZNF446,GTF2H3,TXK,NSD2" MicroRNA hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA_TOP PITA 1.96E-06 1.04E-02 4.69E-06 4.29E-05 15 295 "SMIM15,NCOA1,CACNA1E,FCHO2,PDGFRA,CHD1,AKAP6,STRN3,CLOCK,CSNK1G3,PSME1,SUCO,FOXG1,CNTN2,DOCK9" MicroRNA hsa-miR-449a:PITA hsa-miR-449a:PITA_TOP PITA 1.96E-06 1.04E-02 4.69E-06 4.29E-05 15 295 "SMIM15,NCOA1,CACNA1E,FCHO2,PDGFRA,CHD1,AKAP6,STRN3,CLOCK,CSNK1G3,PSME1,SUCO,FOXG1,CNTN2,DOCK9" MicroRNA hsa-miR-34a:PITA hsa-miR-34a:PITA_TOP PITA 1.96E-06 1.04E-02 4.69E-06 4.29E-05 15 295 "SMIM15,NCOA1,CACNA1E,FCHO2,PDGFRA,CHD1,AKAP6,STRN3,CLOCK,CSNK1G3,PSME1,SUCO,FOXG1,CNTN2,DOCK9" MicroRNA hsa-miR-449b:PITA hsa-miR-449b:PITA_TOP PITA 1.96E-06 1.04E-02 4.69E-06 4.29E-05 15 295 "SMIM15,NCOA1,CACNA1E,FCHO2,PDGFRA,CHD1,AKAP6,STRN3,CLOCK,CSNK1G3,PSME1,SUCO,FOXG1,CNTN2,DOCK9" MicroRNA hsa-miR-301b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.99E-06 1.06E-02 4.76E-06 4.36E-05 17 375 "MCC,STARD13,CFL2,THAP6,GNPTAB,PIGG,RAN,EGLN3,CLIP1,FAM114A1,ERBIN,GRSF1,GPR161,UBC,TENT2,IRF1,LMLN" MicroRNA hsa-miR-874:mirSVR_highEffct hsa-miR-874:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.00E-06 1.07E-02 4.79E-06 4.39E-05 18 417 "LDB2,SLC5A8,SCFD2,ITGBL1,ATAD2B,THAP6,POLE,ZNF586,PIGG,FAM129A,RGS4,ABCA11P,GORAB,STRN,ADGRL3,TEP1,TGM1,AP4S1" MicroRNA hsa-miR-582-3p:PITA hsa-miR-582-3p:PITA_TOP PITA 2.01E-06 1.07E-02 4.80E-06 4.40E-05 14 258 "ABL2,ARHGAP5,ASCL1,KCTD12,CAMK4,PDE4D,LYSMD3,DNM3,TBC1D4,ELK3,MBIP,NPAS3,PCDH17,KCNT2" MicroRNA hsa-miR-3197:mirSVR_lowEffct hsa-miR-3197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.03E-06 1.08E-02 4.85E-06 4.44E-05 23 643 "WDR35,CUL4A,CBLN3,PFKFB2,PTPRVP,FAM53A,NCOR2,ITSN2,COG3,LOC439933,GP6,ARL6IP4,SPON2,TNFRSF19,SDC1,PLEKHA6,GABRA2,ATP8A2,IKBIP,MAST4,ZBTB49,TMPO,MFSD2B" MicroRNA hsa-miR-484:Functional MTI Functional MTI miRTarbase 2.05E-06 1.09E-02 4.90E-06 4.48E-05 28 891 "NYNRIN,ATP1A2,ZNF664,THAP6,HOMER1,HEATR5A,PREPL,G3BP2,FAM129A,TRIM28,SAP18,ARL6IP4,TOMM40L,N4BP2L2,SUCO,NUBPL,UGGT2,KIF21B,STRN,ATP11A,GOLGA3,TEP1,MSH6,GTF2H3,HSP90B1,HSD17B4,LETM1,LMNB1" MicroRNA hsa-miR-199a-5p:PITA hsa-miR-199a-5p:PITA_TOP PITA 2.10E-06 1.12E-02 5.02E-06 4.59E-05 14 259 "RALGAPA1,SEMA6A,PDE4D,KLHL3,SACS,EFNA5,CLIP1,IVNS1ABP,MEGF10,KDM3B,PPARGC1A,ANO4,KLF12,SPRYD7" MicroRNA hsa-miR-199b-5p:PITA hsa-miR-199b-5p:PITA_TOP PITA 2.10E-06 1.12E-02 5.02E-06 4.59E-05 14 259 "RALGAPA1,SEMA6A,PDE4D,KLHL3,SACS,EFNA5,CLIP1,IVNS1ABP,MEGF10,KDM3B,PPARGC1A,ANO4,KLF12,SPRYD7" MicroRNA hsa-miR-31-5p:TargetScan hsa-miR-31-5p TargetScan 2.11E-06 1.12E-02 5.03E-06 4.60E-05 16 336 "ABL2,MAP1B,KIAA1211,APBB2,PDE4D,HOMER1,POU2F1,CLOCK,PREPL,PARPBP,EGLN3,RASA1,RGS4,LATS2,NR5A2,ATP11A" MicroRNA hsa-miR-24:PITA hsa-miR-24:PITA_TOP PITA 2.11E-06 1.12E-02 5.03E-06 4.60E-05 13 223 "APBB2,BCL2L2,NFXL1,ATAD2B,SNCAIP,MATR3,KLHL3,RASA1,TMEM161B,TNFRSF19,ACSL6,KHNYN,IRF1" MicroRNA hsa-miR-516a-5p:mirSVR_lowEffct hsa-miR-516a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.12E-06 1.13E-02 5.05E-06 4.62E-05 20 506 "KIAA1211,ANKRD34B,CDK18,PDGFRA,SNX17,FAM129A,RGS4,DCUN1D2,VEZT,UFM1,JPH4,NPAS3,RBKS,TBC1D1,CRB1,AP4S1,ADAMTS19,SPTSSA,GALP,CHPT1" MicroRNA "ACTGAAA,MIR-30A-3P:MSigDB" "ACTGAAA,MIR-30A-3P:MSigDB" MSigDB 2.14E-06 1.14E-02 5.09E-06 4.66E-05 12 189 "BIRC6,APC,FCHO2,CSNK1G3,LRRTM2,ELK3,DNAJC27,YPEL5,MYT1L,TFDP1,FAM49A,LMNB1" MicroRNA "ACTGAAA,MIR-30E-3P:MSigDB" "ACTGAAA,MIR-30E-3P:MSigDB" MSigDB 2.14E-06 1.14E-02 5.09E-06 4.66E-05 12 189 "BIRC6,APC,FCHO2,CSNK1G3,LRRTM2,ELK3,DNAJC27,YPEL5,MYT1L,TFDP1,FAM49A,LMNB1" MicroRNA hsa-miR-190:PITA hsa-miR-190:PITA_TOP PITA 2.18E-06 1.16E-02 5.18E-06 4.74E-05 11 157 "MAP1B,TBC1D14,PCDH9,LRRTM2,DMXL1,TMEM161B,SMC6,NBEA,TADA1,MEGF10,ANO4" MicroRNA hsa-miR-190b:PITA hsa-miR-190b:PITA_TOP PITA 2.18E-06 1.16E-02 5.18E-06 4.74E-05 11 157 "MAP1B,TBC1D14,PCDH9,LRRTM2,DMXL1,TMEM161B,SMC6,NBEA,TADA1,MEGF10,ANO4" MicroRNA hsa-miR-1282:mirSVR_highEffct hsa-miR-1282:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-06 1.16E-02 5.18E-06 4.74E-05 11 157 "FBRSL1,MYBPC1,ARHGEF7,JAKMIP1,TSEN15,PEAR1,GC,MTUS2,RNF17,TMPO,RNASE11" MicroRNA hsa-miR-520g:PITA hsa-miR-520g:PITA_TOP PITA 2.18E-06 1.16E-02 5.18E-06 4.74E-05 20 507 "ABL2,HOMEZ,APBB2,FAM177A1,CDK17,CFL2,ATAD2B,PITX1,DCAF8,FAM129A,RB1,ETF1,FOXO1,NBEA,PLEKHA6,NR5A2,KDM5B,NPAS3,ANKLE2,KLF12" MicroRNA hsa-miR-520h:PITA hsa-miR-520h:PITA_TOP PITA 2.18E-06 1.16E-02 5.18E-06 4.74E-05 20 507 "ABL2,HOMEZ,APBB2,FAM177A1,CDK17,CFL2,ATAD2B,PITX1,DCAF8,FAM129A,RB1,ETF1,FOXO1,NBEA,PLEKHA6,NR5A2,KDM5B,NPAS3,ANKLE2,KLF12" MicroRNA hsa-miR-548n:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.20E-06 1.17E-02 5.22E-06 4.78E-05 14 260 "MPZL1,FCHO2,CCNB1,CHD1,PFKFB2,THAP6,TOGARAM2,REST,CLIP4,PACRGL,RNF4,CLIP1,SUCO,XPO4" MicroRNA hsa-miR-499-5p:PITA hsa-miR-499-5p:PITA_TOP PITA 2.22E-06 1.18E-02 5.26E-06 4.82E-05 13 224 "MAP1B,STXBP6,NOVA1,CFL2,PGGT1B,GPR180,HECTD1,ARGLU1,FGF9,VEZT,SLC12A2,NR5A2,EML4" MicroRNA hsa-miR-639:mirSVR_lowEffct hsa-miR-639:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.25E-06 1.19E-02 5.33E-06 4.88E-05 20 508 "SEMA6A,ATP1A2,FCGR2C,CD1D,SNX6,BOD1L1,ADGRF3,HECTD1,SNCAIP,NOS1AP,SNX17,EIF2B1,MAEA,PAICS,TMEM183A,PCDH17,ADAMTS19,UBE2K,PLB1,ZBED3-AS1" MicroRNA hsa-miR-187:mirSVR_highEffct hsa-miR-187:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.26E-06 1.20E-02 5.36E-06 4.91E-05 12 190 "MDM4,ATP2B4,ODC1,CD1E,WDFY2,RNF31,ARSK,FGF9,PPARGC1A,MAST4,GUF1,LHX9" MicroRNA hsa-miR-1827:PITA hsa-miR-1827:PITA_TOP PITA 2.30E-06 1.22E-02 5.45E-06 4.99E-05 14 261 "SEMA6A,CACNA1E,FCHO2,SPATA18,CEP350,FAM172A,SLC30A6,SCYL2,KIF21B,NMNAT2,IQGAP2,KDM3B,IGF1,ZBTB41" MicroRNA hsa-miR-564:mirSVR_lowEffct hsa-miR-564:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-06 1.23E-02 5.48E-06 5.02E-05 20 509 "HOMEZ,PNP,PCDH9,DCLK1,FAM163A,TAPT1,POLE,SPATA18,LATS2,DHRS2,TACC3,FOXO1,FLT1,FTLP10,LIMCH1,MRPS27,ZNF544,TBC1D1,STON1,RAB2B" MicroRNA hsa-miR-142-5p:Functional MTI Functional MTI miRTarbase 2.33E-06 1.24E-02 5.51E-06 5.05E-05 13 225 "ULK1,SNX24,CDKL2,UHMK1,PDE4D,UBXN2A,CEP120,EGLN3,REST,EFNA5,SPIC,MSH6,ZNF324B" MicroRNA hsa-miR-567:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-06 1.27E-02 5.64E-06 5.17E-05 12 191 "TMEM132B,RGS5,CFL2,DCAF8,MBNL2,SAP18,CCDC38,NT5C1B,TECRL,IGF1,ZFHX2,NT5C1B-RDH14" MicroRNA hsa-miR-320c:TargetScan hsa-miR-320c TargetScan 2.39E-06 1.27E-02 5.64E-06 5.17E-05 22 602 "NLN,RGS5,APBB2,PPP1R3E,CACNA1E,NRL,PCSK1,PDE4D,CFL2,NUP37,BOD1L1,LTB4R,RASA1,EIF2B1,EFS,PCGF3,GABRB1,HSPH1,INSM2,ATP11A,GOLGA3,LMLN" MicroRNA hsa-miR-320b:TargetScan hsa-miR-320b TargetScan 2.39E-06 1.27E-02 5.64E-06 5.17E-05 22 602 "NLN,RGS5,APBB2,PPP1R3E,CACNA1E,NRL,PCSK1,PDE4D,CFL2,NUP37,BOD1L1,LTB4R,RASA1,EIF2B1,EFS,PCGF3,GABRB1,HSPH1,INSM2,ATP11A,GOLGA3,LMLN" MicroRNA hsa-miR-320d:TargetScan hsa-miR-320d TargetScan 2.39E-06 1.27E-02 5.64E-06 5.17E-05 22 602 "NLN,RGS5,APBB2,PPP1R3E,CACNA1E,NRL,PCSK1,PDE4D,CFL2,NUP37,BOD1L1,LTB4R,RASA1,EIF2B1,EFS,PCGF3,GABRB1,HSPH1,INSM2,ATP11A,GOLGA3,LMLN" MicroRNA hsa-miR-320a:TargetScan hsa-miR-320a TargetScan 2.39E-06 1.27E-02 5.64E-06 5.17E-05 22 602 "NLN,RGS5,APBB2,PPP1R3E,CACNA1E,NRL,PCSK1,PDE4D,CFL2,NUP37,BOD1L1,LTB4R,RASA1,EIF2B1,EFS,PCGF3,GABRB1,HSPH1,INSM2,ATP11A,GOLGA3,LMLN" MicroRNA hsa-miR-1301:PITA hsa-miR-1301:PITA_TOP PITA 2.40E-06 1.28E-02 5.68E-06 5.20E-05 14 262 "CDK17,PDE4D,ATAD2B,G3BP2,TMEM161B,TOMM40L,SUCO,RASA3,FBXO11,ACIN1,PPARGC1A,RIMBP2,KLF12,LMNB1" MicroRNA hsa-miR-486-5p:PITA hsa-miR-486-5p:PITA_TOP PITA 2.54E-06 1.35E-02 5.99E-06 5.49E-05 10 129 "BIRC6,ARHGAP5,FCHO2,CEP350,G3BP2,RGS4,FOXO1,GOLGA3,NSD2,IGF1" MicroRNA "GTGTTGA,MIR-505:MSigDB" "GTGTTGA,MIR-505:MSigDB" MSigDB 2.54E-06 1.35E-02 6.00E-06 5.49E-05 9 101 "PCDH9,PDE4D,SLC25A3,STRN3,VEZT,SLC12A2,YPEL5,LRCH1,SELENOI" MicroRNA hsa-miR-4768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-06 1.39E-02 6.17E-06 5.65E-05 23 653 "MMP17,HOMEZ,APAF1,NOP14,EPGN,MPHOSPH8,EIF2AK2,SPATA18,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,UTP15,PLEKHA6,SLC30A6,GRSF1,ZBTB49,ATP6V0A2,HSP90B1,ZNF324B,PGAM5" MicroRNA hsa-miR-3163:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-06 1.41E-02 6.24E-06 5.71E-05 16 342 "WDR35,MSH2,MYBPC1,FCHO2,CCNB1,POU2F1,COCH,MTX3,ELK3,ARSK,CWC27,CLIP1,BRMS1L,PLEKHA6,METAP2,LMNB1" MicroRNA hsa-miR-1298:mirSVR_highEffct hsa-miR-1298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.69E-06 1.43E-02 6.35E-06 5.81E-05 13 228 "DDX55,PROZ,CDKL2,PCDH9,ITGBL1,HOMER1,F10,SF3B6,ZNF667,GABRB1,NMNAT2,LILRB1,TXK" MicroRNA hsa-miR-196a-5p:Functional MTI Functional MTI miRTarbase 2.72E-06 1.45E-02 6.40E-06 5.86E-05 15 303 "NFKBIA,RAB29,PNP,NRXN1,CEP120,TMEM161B,NTN4,SBNO1,SAP18,PCGF3,FOXO1,BRMS1L,SLC30A6,POTEM,SPTSSA" MicroRNA hsa-miR-1276:PITA hsa-miR-1276:PITA_TOP PITA 2.74E-06 1.46E-02 6.46E-06 5.92E-05 16 343 "SEMA6A,CUL4A,APC,BTF3,PGGT1B,ATAD2B,ZFYVE16,SREK1,G3BP2,PLEKHA6,KDM3B,NFASC,PSME4,KLF12,ZBTB41,LMNB1" MicroRNA hsa-miR-153:PITA hsa-miR-153:PITA_TOP PITA 2.74E-06 1.46E-02 6.46E-06 5.92E-05 16 343 "APC,SLC4A4,CFL2,CHD1,BOD1L1,AKAP6,ITSN2,DNM3,CEP350,KLHL3,GNPDA2,RASA1,TBC1D19,FOXO1,PPARGC1A,XPO4" MicroRNA hsa-miR-650:Functional MTI Functional MTI miRTarbase 2.79E-06 1.48E-02 6.55E-06 6.00E-05 18 427 "NDRG2,CCNB1,PDGFRA,PIGR,EPGN,NCOR2,MPHOSPH8,SUPT7L,SLC35F6,TMEM33,TCTN2,ARSK,MRPS14,DCAF11,SNRNP35,COX18,ATP6V0A2,GUF1" MicroRNA hsa-miR-654-5p:mirSVR_highEffct hsa-miR-654-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.82E-06 1.50E-02 6.63E-06 6.07E-05 19 471 "FAM193A,CD84,RAB29,PNP,PFKFB2,GNPTAB,RGS12,RNF4,TOMM40L,THADA,JPH4,RNF212,TGFBI,ZFHX2,SDR39U1,LHX9,KIR2DL4,KIR3DL2,RMST" MicroRNA hsa-miR-31:PITA hsa-miR-31:PITA_TOP PITA 2.82E-06 1.50E-02 6.64E-06 6.08E-05 13 229 "MAP1B,APBB2,STARD13,HOMER1,PREPL,DCAF8,G3BP2,RASA1,LATS2,VEZT,NR5A2,UBE2K,IRF1" MicroRNA "TATTATA,MIR-374:MSigDB" "TATTATA,MIR-374:MSigDB" MSigDB 2.87E-06 1.52E-02 6.73E-06 6.16E-05 14 266 "ARHGAP5,ASCL1,NCOA1,STARD13,NOVA1,PDE4D,HECTD1,HOMER1,MBNL2,PCGF3,FOXG1,FOXO1,ARHGEF40,PPARGC1A" MicroRNA hsa-miR-150-5p:TargetScan hsa-miR-150-5p TargetScan 2.87E-06 1.52E-02 6.73E-06 6.16E-05 14 266 "MAP1B,MDM4,APC,CAST,CFL2,PIGG,KLHL3,ETF1,NBEA,ATP8A2,NFASC,GTF3C2,HSP90B1,FAM49A" MicroRNA hsa-miR-766-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.87E-06 1.53E-02 6.74E-06 6.17E-05 22 609 "CAD,MPZL1,RILPL1,CCNB1,PIGR,POLE,UBXN2A,PRKD1,FCRL2,SREK1,MTX3,FAM129A,PCBD2,PAICS,ZNF667,KDM5B,RAPGEF6,COX18,TGFBI,UBC,LETM1,SPATA13" MicroRNA hsa-miR-371a-5p:Functional MTI Functional MTI miRTarbase 2.96E-06 1.57E-02 6.94E-06 6.35E-05 16 345 "TMEM132B,PKP1,GNPTAB,HEATR5A,RABGAP1L,DCUN1D2,DLEU1,PAICS,ZNF446,OXGR1,UTP20,GOLGA3,COX18,TMPO,RIMBP2,DCP2" MicroRNA hsa-miR-518a-3p:mirSVR_highEffct hsa-miR-518a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.96E-06 1.57E-02 6.94E-06 6.35E-05 12 195 "ARHGEF7,CD1E,ZNF664,LOC439933,WDR1,DNMT3A,CLIP4,DLEU1,ZCCHC8,FBXO11,LPIN1,KMT5A" MicroRNA hsa-miR-4659a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.96E-06 1.58E-02 6.94E-06 6.36E-05 13 230 "RALGAPA1,ASCL1,KCTD12,EPGN,MATR3,FAM81B,ATP6AP1L,TRAPPC13,GORAB,GABRB1,PCDH17,ACSL6,ZDHHC20" MicroRNA hsa-miR-4659b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.96E-06 1.58E-02 6.94E-06 6.36E-05 13 230 "RALGAPA1,ASCL1,KCTD12,EPGN,MATR3,FAM81B,ATP6AP1L,TRAPPC13,GORAB,GABRB1,PCDH17,ACSL6,ZDHHC20" MicroRNA hsa-miR-33a:PITA hsa-miR-33a:PITA_TOP PITA 2.96E-06 1.58E-02 6.94E-06 6.36E-05 13 230 "KCTD12,NOVA1,CAMK4,FCHO2,PDGFRA,CHD1,HOMER1,ZFYVE16,SREK1,NTN4,PPARGC1A,RIMBP2,KIF3C" MicroRNA hsa-miR-25-3p:Functional MTI Functional MTI miRTarbase 3.01E-06 1.60E-02 7.04E-06 6.45E-05 20 518 "MAP1B,CAD,CCNB1,DHX9,F11R,DHFR,SUPT7L,FAM129A,TMEM33,TXNDC15,LATS2,RNF4,PCBD2,FNIP1,G2E3,GOLGA3,GUF1,IL6ST,FAM49A,LETM1" MicroRNA hsa-miR-1537:mirSVR_highEffct hsa-miR-1537:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-06 1.63E-02 7.18E-06 6.57E-05 16 346 "ARL1,CCNA1,TSEN15,EIF2B1,BORA,ETF1,N4BP2L2,TMED2,ADGRL3,RIMBP2,PAPPA2,YTHDC2,C12orf73,ANKS1B,CHPT1,AXDND1" MicroRNA hsa-miR-361-3p:mirSVR_highEffct hsa-miR-361-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-06 1.63E-02 7.18E-06 6.57E-05 16 346 "HOMEZ,CD1D,PCDH9,FCRL5,FAM129A,RNF4,ELF1,STAB2,RUBCNL,NUBPL,SNRPF,JPH4,SULT1E1,TGM1,ZBTB49,ADAMTS19" MicroRNA hsa-miR-33b:PITA hsa-miR-33b:PITA_TOP PITA 3.11E-06 1.65E-02 7.27E-06 6.65E-05 13 231 "KCTD12,NOVA1,CAMK4,FCHO2,PDGFRA,CHD1,HOMER1,ZFYVE16,SREK1,NTN4,PPARGC1A,RIMBP2,KIF3C" MicroRNA hsa-miR-7110-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-06 1.82E-02 8.00E-06 7.33E-05 16 349 "NLN,COG6,ASCL1,PPP1R3E,SMIM14,LRRTM2,ATG10,KLHL12,ATP6AP1L,ARL6IP4,FGF9,PLEKHA6,LIMCH1,PCDH17,STRN,LHX9" MicroRNA hsa-miR-512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-06 1.83E-02 8.06E-06 7.38E-05 15 309 "BCL2L2,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,RNF4,N4BP2L2,ZNF446,SLC8A1,ADAM17,GTF2H3,TXK,IL6ST" MicroRNA hsa-miR-4524b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.58E-06 1.90E-02 8.36E-06 7.65E-05 13 234 "NLN,ATP1A2,SLC5A6,CD1D,PCGF3,GABRB1,ZNF274,PPARGC1A,GJB2,ACSL6,GTF2H3,PGAM5,KIT" MicroRNA hsa-miR-142-3p:PITA hsa-miR-142-3p:PITA_TOP PITA 3.65E-06 1.94E-02 8.52E-06 7.80E-05 12 199 "ABL2,APC,CFL2,HECTD1,STRN3,RCHY1,PCGF3,SUCO,FAM114A1,EML4,BAZ1A,ZBTB41" MicroRNA hsa-miR-129-3p:mirSVR_lowEffct hsa-miR-129-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.70E-06 1.97E-02 8.63E-06 7.90E-05 31 1079 "APAF1,NCOA1,BCL2L2,MPZL1,RILPL1,RCBTB2,SNX6,AKAP6,RCHY1,ITSN2,EPS8L1,PARPBP,TSEN15,ZNF329,SETDB2,TOMM40L,GORAB,SUCO,FBXO11,THADA,NMNAT2,ATP8A2,MRPS27,NT5C1B,TMPO,HPCAL1,VRK2,JCHAIN,FAM151B,FAM71C,PABPN1" MicroRNA hsa-miR-634:PITA hsa-miR-634:PITA_TOP PITA 3.71E-06 1.97E-02 8.65E-06 7.92E-05 14 272 "SLC4A4,NRL,CKMT2,G3BP2,ARGLU1,ZNF219,SLC8A1,ERBIN,ADAM17,ADGRL3,TFDP1,HMGCR,ZNF470,ZMYM2" MicroRNA hsa-miR-3185:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.74E-06 1.99E-02 8.73E-06 7.99E-05 11 166 "HOMEZ,NCOA1,ARHGEF7,VCAN,ZNF256,SAP18,TLR6,TM9SF1,KDM5B,HGFAC,ZDHHC20" MicroRNA "ATCATGA,MIR-433:MSigDB" "ATCATGA,MIR-433:MSigDB" MSigDB 3.80E-06 2.02E-02 8.85E-06 8.10E-05 9 106 "B4GALT3,CDK17,SLC25A3,CEP135,TMEM33,TBC1D19,CENPJ,SRP54,PPARGC1A" MicroRNA hsa-miR-1224-3p:PITA hsa-miR-1224-3p:PITA_TOP PITA 3.80E-06 2.02E-02 8.85E-06 8.10E-05 9 106 "ATAD2B,HECTD1,DNMT3A,FNIP1,SUCO,ZNF544,ATP11A,KLF12,PABPN1" MicroRNA hsa-miR-324-5p:mirSVR_highEffct hsa-miR-324-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.82E-06 2.03E-02 8.88E-06 8.13E-05 16 352 "SLAMF6,LINC02347,FCHO2,ITGBL1,TOGARAM2,PM20D1,RABGAP1L,RAN,RNASEL,FOXO1,RUBCNL,FBXO11,CYP1B1-AS1,OXGR1,METAP2,CRB1" MicroRNA "TTGGAGA,MIR-519E:MSigDB" "TTGGAGA,MIR-519E:MSigDB" MSigDB 3.82E-06 2.03E-02 8.89E-06 8.14E-05 10 135 "NCOA1,SLC4A4,NFATC4,PDGFRA,POU2F1,G3BP2,KHNYN,MAEL,UBE2K,NSD2" MicroRNA "TTGGAGA,MIR-515-5P:MSigDB" "TTGGAGA,MIR-515-5P:MSigDB" MSigDB 3.82E-06 2.03E-02 8.89E-06 8.14E-05 10 135 "NCOA1,SLC4A4,NFATC4,PDGFRA,POU2F1,G3BP2,KHNYN,MAEL,UBE2K,NSD2" MicroRNA hsa-miR-548a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.84E-06 2.04E-02 8.93E-06 8.17E-05 12 200 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST,IFT88" MicroRNA hsa-miR-337-5p:mirSVR_highEffct hsa-miR-337-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.84E-06 2.04E-02 8.93E-06 8.17E-05 12 200 "WDFY2,FCRL2,PIGG,DMXL1,PPP2R3C,N4BP2L2,C1orf112,UGGT2,ERAP1,PSME4,GOLGA3,PLB1" MicroRNA hsa-let-7d-5p:Functional MTI Functional MTI miRTarbase 3.84E-06 2.04E-02 8.93E-06 8.18E-05 17 394 "MDM4,NCOA1,SLC5A6,HOMER1,BRI3BP,CEP135,SNX17,SREK1,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,SLC30A6,POTEM,ZBTB37,STRN" MicroRNA "TTGGGAG,MIR-150:MSigDB" "TTGGGAG,MIR-150:MSigDB" MSigDB 3.86E-06 2.05E-02 8.97E-06 8.21E-05 8 80 "ZMYM5,KLHL3,ARGLU1,ETF1,TADA1,IKBIP,GTF3C2,IGF1" MicroRNA hsa-miR-541:mirSVR_highEffct hsa-miR-541:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.92E-06 2.09E-02 9.11E-06 8.34E-05 19 482 "FAM193A,CD84,RAB29,PNP,GNPTAB,RGS12,RNF4,TOMM40L,THADA,JPH4,RNF212,ZFHX2,CCDC169,SDR39U1,LHX9,NPHS2,KIR2DL4,KIR3DL2,RMST" MicroRNA hsa-miR-517a:mirSVR_highEffct hsa-miR-517a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.04E-06 2.15E-02 9.38E-06 8.59E-05 12 201 "SMIM14,C12orf65,SACS,GUSBP3,FCAR,NDUFAF7,FMO1,EFR3B,DOCK9,LINC01551,NPHS2,LMNB1" MicroRNA hsa-miR-1250:mirSVR_lowEffct hsa-miR-1250:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-06 2.19E-02 9.52E-06 8.72E-05 20 529 "BLZF1,NOP14,ARHGEF7,ADGRD1,NOVA1,CBLN3,RGSL1,C12orf65,SNX17,TSEN15,DNMT3A,SMC6,RGS12,POLR1D,LIMCH1,ADGRL3,C12orf73,TMEM178A,FIP1L1,ZNF304" MicroRNA "AATGTGA,MIR-23B:MSigDB" "AATGTGA,MIR-23B:MSigDB" MSigDB 4.11E-06 2.19E-02 9.52E-06 8.72E-05 17 396 "MCFD2,NCOA1,SLC4A4,NRXN1,CSNK1G3,DNM3,DMXL1,G3BP2,SUCO,FBXO11,TADA1,PPARGC1A,ANO4,TMPO,NSD2,IRF1,NUAK2" MicroRNA "AATGTGA,MIR-23A:MSigDB" "AATGTGA,MIR-23A:MSigDB" MSigDB 4.11E-06 2.19E-02 9.52E-06 8.72E-05 17 396 "MCFD2,NCOA1,SLC4A4,NRXN1,CSNK1G3,DNM3,DMXL1,G3BP2,SUCO,FBXO11,TADA1,PPARGC1A,ANO4,TMPO,NSD2,IRF1,NUAK2" MicroRNA hsa-miR-577:PITA hsa-miR-577:PITA_TOP PITA 4.19E-06 2.23E-02 9.69E-06 8.88E-05 23 672 "RALGAPA1,MAP1B,APC,ZNF595,NRXN1,BRI3BP,DMXL1,G3BP2,GNPDA2,TSEN15,MBNL2,CLIP1,ZCCHC8,IVNS1ABP,PDS5B,KDM5B,PPARGC1A,PSME4,KLF12,DCP2,IGF1,SPTSSA,LIG4" MicroRNA hsa-miR-499a-5p:TargetScan hsa-miR-499a-5p TargetScan 4.19E-06 2.23E-02 9.69E-06 8.88E-05 15 314 "APC,NOVA1,CFL2,GPR180,ITGBL1,MTX3,ARGLU1,FNIP1,FGF9,FOXG1,EML4,MSH6,DCP2,ANKS1B,KIF3C" MicroRNA hsa-miR-136*:mirSVR_highEffct hsa-miR-136*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.20E-06 2.23E-02 9.72E-06 8.90E-05 11 168 "MCFD2,CCNA1,CAST,ZNF664,UGT2A3,MARVELD2,USP44,PKD2L2,RBKS,ZBTB37,VRK2" MicroRNA hsa-miR-6807-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-06 2.28E-02 9.90E-06 9.06E-05 21 577 "PPP1R12B,BCL2L2,CAD,CAMK4,RILPL1,SMIM14,NCOR2,FCRL2,F11R,RABGAP1L,MTX3,SLC35F6,TMEM33,TXNDC15,SBNO1,PAICS,PPIP5K2,SNRNP35,ZBTB49,GTF2H3,TXK" MicroRNA hsa-miR-135b*:mirSVR_highEffct hsa-miR-135b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.35E-06 2.31E-02 1.01E-05 9.20E-05 18 441 "ATP2B4,TAF1B,PCCA,CCDC122,WDFY2,COG3,FBXL5,NTN4,ETF1,DNAJC27,SUCO,CCDC88A,ACIN1,GABRA2,NMNAT2,CNTN2,LTB4R2,ZNF876P" MicroRNA hsa-miR-382:PITA hsa-miR-382:PITA_TOP PITA 4.39E-06 2.33E-02 1.01E-05 9.28E-05 14 276 "NDRG2,PCDH9,CRHBP,MATR3,COCH,MBNL2,NBEA,DHRS4,TMED2,ANO4,KMT5A,KLF12,SLAIN1,YTHDC2" MicroRNA hsa-miR-638:mirSVR_lowEffct hsa-miR-638:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.39E-06 2.34E-02 1.02E-05 9.29E-05 17 398 "ADD1,DHX37,TAF1B,GPR180,CPNE6,POU2F1,DHX9,CLIP4,STAB2,CCDC92,CGREF1,NFASC,TMED2,AP4S1,DNAH10,MFSD2B,RMST" MicroRNA "CTACTGT,MIR-199A:MSigDB" "CTACTGT,MIR-199A:MSigDB" MSigDB 4.71E-06 2.50E-02 1.09E-05 9.95E-05 11 170 "FAM193A,ASCL1,SLC4A4,NOVA1,CDK17,PDGFRA,GLT8D2,DNMT3A,PDS5B,EML4,RAB2B" MicroRNA hsa-miR-496:PITA hsa-miR-496:PITA_TOP PITA 4.71E-06 2.50E-02 1.09E-05 9.95E-05 11 170 "MAP1B,NCOA1,NOVA1,PRKD1,RASA1,MAEA,MYT1L,NPAS3,DOCK9,KHNYN,ZBTB41" MicroRNA hsa-miR-940:PITA hsa-miR-940:PITA_TOP PITA 4.76E-06 2.53E-02 1.10E-05 1.01E-04 14 278 "MAP1B,PITPNM2,FAM193A,CFL2,DCAF8,FAM172A,ETF1,SLC30A6,KIF21B,NMNAT2,JPH4,IGF1,KIF3C,PABPN1" MicroRNA hsa-miR-23a*:mirSVR_highEffct hsa-miR-23a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.85E-06 2.58E-02 1.12E-05 1.02E-04 17 401 "SMIM15,MCFD2,ATP1A2,UBXN2A,COG3,DLEU1,HSD17B7,VEZT,CGREF1,DCAF11,COMMD6,PPARGC1A,METAP2,GOLGA3,AP4S1,KCNJ9,EEF1AKMT1" MicroRNA hsa-miR-580-3p:Functional MTI Functional MTI miRTarbase 4.96E-06 2.64E-02 1.14E-05 1.05E-04 10 139 "TAF1B,NUP37,CLOCK,MEMO1,POLR1D,IKBIP,STRN,ACSL6,HTR2A,C12orf73" MicroRNA hsa-miR-1275:mirSVR_highEffct hsa-miR-1275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.00E-06 2.66E-02 1.15E-05 1.05E-04 27 882 "NDRG2,CENPBD1P1,ZNF542P,DCLK1,TM9SF2,ATAD2B,GNPTAB,COG3,COCH,G3BP2,ATG10,POLR1D,TRIM28,LRRN2,VEZT,FBXO11,CIDEB,JPH4,LRCH1,MAST4,EML4,RNF212,HAL,TXK,ZNF26,MZF1,SPTSSA" MicroRNA hsa-miR-4668-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.01E-06 2.66E-02 1.15E-05 1.06E-04 17 402 "MDM4,PDE4D,PDGFRA,EPN1,HECTD1,GNPTAB,LACC1,MTX3,ARGLU1,REST,LATS2,KLHL12,SDC1,SH3BP2,UHRF1BP1L,PPARGC1A,SPIC" MicroRNA hsa-miR-3529-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.10E-06 2.71E-02 1.17E-05 1.08E-04 8 83 "MCC,MDM4,SLC5A6,THAP6,BRI3BP,TBC1D19,PCGF3,PABPN1" MicroRNA hsa-miR-129*:mirSVR_lowEffct hsa-miR-129*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-06 2.73E-02 1.18E-05 1.08E-04 31 1097 "NCOA1,BCL2L2,MPZL1,RILPL1,RCBTB2,SNX6,AKAP6,RCHY1,ITSN2,EPS8L1,PARPBP,TSEN15,ZNF329,IPO4,SETDB2,TOMM40L,GORAB,SUCO,FBXO11,THADA,NMNAT2,ATP8A2,MRPS27,NT5C1B,TMPO,HPCAL1,VRK2,JCHAIN,FAM151B,FAM71C,PABPN1" MicroRNA hsa-miR-1264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.16E-06 2.74E-02 1.19E-05 1.09E-04 9 110 "KIAA1211,PCDH9,CLIP4,SDC1,ZNF446,KLF12,LTB4R2,ZNF84,LHX9" MicroRNA hsa-miR-496.1:TargetScan hsa-miR-496.1 TargetScan 5.16E-06 2.74E-02 1.19E-05 1.09E-04 9 110 "NOVA1,DRAM1,LIMCH1,MYT1L,GABRB1,NPAS3,KHNYN,KLF12,HSP90B1" MicroRNA hsa-miR-889:PITA hsa-miR-889:PITA_TOP PITA 5.17E-06 2.75E-02 1.19E-05 1.09E-04 14 280 "ATP2B4,PCSK1,BOD1L1,HOMER1,LRRTM2,DCAF8,ZFYVE16,CCDC88A,SLC12A2,N4BP2,SLC22A5,NR5A2,TDG,CHPT1" MicroRNA hsa-miR-6809-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-06 2.90E-02 1.25E-05 1.15E-04 15 321 "COG6,ASCL1,MYBPC1,CD84,UHMK1,SMIM14,NUP37,ATP6AP1L,FOXO1,N4BP2,ZNF667,CENPJ,XPO4,MSH6,TMEM174" MicroRNA hsa-miR-1250-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-06 2.91E-02 1.25E-05 1.15E-04 12 207 "SMIM14,TOGARAM2,HEATR5A,DMXL1,RAN,RNASEL,SLC30A6,ZNF274,MSH6,TNR,UBE2K,SPTSSA" MicroRNA hsa-miR-23b*:mirSVR_highEffct hsa-miR-23b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.52E-06 2.94E-02 1.27E-05 1.16E-04 17 405 "SMIM15,MCFD2,ATP1A2,UBXN2A,COG3,DLEU1,HSD17B7,VEZT,CGREF1,DCAF11,COMMD6,PPARGC1A,METAP2,GOLGA3,AP4S1,KCNJ9,EEF1AKMT1" MicroRNA hsa-miR-135a:PITA hsa-miR-135a:PITA_TOP PITA 5.56E-06 2.96E-02 1.28E-05 1.17E-04 18 449 "APC,NCOA1,ARHGEF7,FCHO2,LDB2,PGGT1B,GPR180,CSNK1G3,NOS1AP,TBC1D4,LATS2,ELK3,EFS,FOXO1,NBEA,TADA1,MYT1L,ANO4" MicroRNA hsa-miR-135b:PITA hsa-miR-135b:PITA_TOP PITA 5.56E-06 2.96E-02 1.28E-05 1.17E-04 18 449 "APC,NCOA1,ARHGEF7,FCHO2,LDB2,PGGT1B,GPR180,CSNK1G3,NOS1AP,TBC1D4,LATS2,ELK3,EFS,FOXO1,NBEA,TADA1,MYT1L,ANO4" MicroRNA hsa-miR-4486:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-06 3.00E-02 1.29E-05 1.18E-04 10 141 "MYBPC1,PDE6B,PIGR,SBNO1,PCBD2,ZCCHC8,PAICS,UFM1,GUF1,UBC" MicroRNA hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 5.64E-06 3.00E-02 1.29E-05 1.18E-04 13 244 "BLZF1,BCL2L2,NCOR2,CEP350,SDC1,FLT1,CCDC88A,NR5A2,MYT1L,GABRB1,NPAS3,NFASC,GOLGA3" MicroRNA hsa-miR-216a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-06 3.00E-02 1.29E-05 1.18E-04 13 244 "ADD1,NLN,RILPL1,LYSMD3,ITSN2,ZNF329,TOMM40L,SUCO,WDCP,MRPS27,ZBTB37,COX18,HAL" MicroRNA hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 5.64E-06 3.00E-02 1.29E-05 1.18E-04 13 244 "BLZF1,BCL2L2,NCOR2,CEP350,SDC1,FLT1,CCDC88A,NR5A2,MYT1L,GABRB1,NPAS3,NFASC,GOLGA3" MicroRNA hsa-miR-3681-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-06 3.00E-02 1.29E-05 1.18E-04 13 244 "ADD1,NLN,RILPL1,LYSMD3,ITSN2,ZNF329,TOMM40L,SUCO,WDCP,MRPS27,ZBTB37,COX18,HAL" MicroRNA hsa-miR-6829-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.67E-06 3.01E-02 1.30E-05 1.19E-04 15 322 "ABL2,SLC4A4,TAF1B,RILPL1,PIWIL1,POU2F1,PIGG,RABGAP1L,C14orf119,EFNA5,VEZT,UGGT2,NT5C1B,FAM151B,NT5C1B-RDH14" MicroRNA hsa-miR-6791-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.67E-06 3.01E-02 1.30E-05 1.19E-04 15 322 "ABL2,SLC4A4,TAF1B,RILPL1,PIWIL1,POU2F1,PIGG,RABGAP1L,C14orf119,EFNA5,VEZT,UGGT2,NT5C1B,FAM151B,NT5C1B-RDH14" MicroRNA hsa-miR-4781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.03E-06 3.20E-02 1.38E-05 1.26E-04 12 209 "COG6,ATP1A2,CD1D,AKAP6,HEATR5A,DMXL1,RABGAP1L,SLC35F6,NDUFAF7,NUBPL,TMPO,PGAM5" MicroRNA hsa-miR-10b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.10E-06 3.24E-02 1.39E-05 1.27E-04 8 85 "PCSK1,WDFY2,POLE,MATR3,DNAJC27,SUCO,ZBTB49,LMNB1" MicroRNA hsa-miR-4463:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.10E-06 3.24E-02 1.39E-05 1.27E-04 8 85 "MAP1B,CAD,UHMK1,THAP6,TBC1D4,ARGLU1,TBC1D19,BRMS1L" MicroRNA hsa-miR-886-3p:mirSVR_highEffct hsa-miR-886-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-06 3.24E-02 1.39E-05 1.27E-04 8 85 "HOMEZ,FCHO2,LDB2,NR1H4,F10,NUBPL,ANO4,RNF212" MicroRNA hsa-miR-4778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-06 3.30E-02 1.42E-05 1.30E-04 11 175 "RALGAPA1,RGS5,ASCL1,ATP1A2,ZNF664,UGT2B28,HEATR5A,RABGAP1L,ATP6AP1L,SDC1,GABRB1" MicroRNA hsa-miR-4423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-06 3.36E-02 1.44E-05 1.32E-04 12 210 "TMEM132B,CD1D,PIWIL1,CSNK1G3,SBNO1,ATP6AP1L,ZNF446,COMMD6,TEP1,GRSF1,GPR161,PGAM5" MicroRNA hsa-miR-6836-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.33E-06 3.36E-02 1.44E-05 1.32E-04 12 210 "PITX1,POU2F1,PIGG,RABGAP1L,C14orf119,EFNA5,VEZT,UGGT2,NT5C1B,STARD4,FAM151B,NT5C1B-RDH14" MicroRNA hsa-miR-6504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.45E-06 3.43E-02 1.47E-05 1.35E-04 16 367 "GPR180,SMIM14,POU2F1,TTC37,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,N4BP2L2,ZNF446,SLC12A2,GRSF1,GTF2H3,TXK,SELENOI" MicroRNA hsa-miR-6821-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.59E-06 3.50E-02 1.50E-05 1.37E-04 14 286 "ABL2,PIGG,SLC35F6,DCUN1D2,DLEU1,TLR6,PCBD2,ZCCHC8,NUBPL,PAICS,DCP2,ZNF84,IRF1,SPATA13" MicroRNA hsa-miR-6501-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.64E-06 3.53E-02 1.51E-05 1.38E-04 12 211 "TMEM132B,CD1D,PIWIL1,CSNK1G3,SBNO1,ATP6AP1L,ZNF446,COMMD6,TEP1,GRSF1,GPR161,PGAM5" MicroRNA hsa-miR-4722-5p:Functional MTI Functional MTI miRTarbase 6.82E-06 3.63E-02 1.55E-05 1.42E-04 21 595 "HOMEZ,APAF1,NOP14,CAD,CDK18,CFL2,UBXN2A,MPHOSPH8,EIF2AK2,SLC35F6,DTD2,TBC1D19,ARSK,UTP15,SLC30A6,GRSF1,ATP6V0A2,DCP2,PGAM5,LETM1,PABPN1" MicroRNA hsa-miR-516a-3p:PITA hsa-miR-516a-3p:PITA_TOP PITA 6.96E-06 3.70E-02 1.58E-05 1.45E-04 12 212 "CUL4A,RILPL1,FCHO2,PIK3C2B,MBNL2,IVNS1ABP,PCDH17,EML4,KHNYN,FZD10,TNR,YTHDC2" MicroRNA hsa-miR-3177:mirSVR_lowEffct hsa-miR-3177:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.98E-06 3.71E-02 1.59E-05 1.45E-04 19 502 "CUL4A,ASTN1,ADGRD1,PITX1,PKP1,THTPA,PIGG,NR1I3,REST,ABCA11P,STAB2,SLC34A2,CCDC92,ANKLE2,KMT5C,GPR161,NSD2,LAD1,PABPN1" MicroRNA hsa-miR-1324:PITA hsa-miR-1324:PITA_TOP PITA 7.07E-06 3.76E-02 1.61E-05 1.47E-04 15 328 "SEMA6A,APBB2,RILPL1,CDK17,UBXN2A,DMXL1,ETF1,RELL1,SUCO,FOXO1,FLT3,SLC8A1,SLC12A2,MYT1L,TFDP1" MicroRNA hsa-miR-106b*:mirSVR_lowEffct hsa-miR-106b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.08E-06 3.77E-02 1.61E-05 1.47E-04 20 549 "ADCY4,WDR19,NCOA1,ZNF542P,PGGT1B,ADGRF3,HOMER1,SPATA18,COG3,WDR1,NR1H4,RGS12,NTN4,VEZT,BRMS1L,ARHGEF40,DCAF11,ADAMTS19,TENT2,PABPN1" MicroRNA hsa-miR-3178:mirSVR_lowEffct hsa-miR-3178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.30E-06 3.88E-02 1.66E-05 1.52E-04 11 178 "FCHO2,FCRLB,CCDC122,WDFY2,PITX1,EIF2AK2,WDR1,MARVELD2,POLK,RASA3,ZNF274" MicroRNA hsa-miR-649:PITA hsa-miR-649:PITA_TOP PITA 7.30E-06 3.88E-02 1.66E-05 1.52E-04 12 213 "NCOA1,ATP2B4,FCHO2,ZNF595,HOMER1,LRRTM2,CCDC88A,PCDH17,PPARGC1A,TMED2,KMT5A,ADAMTS19" MicroRNA hsa-miR-373-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.39E-06 3.93E-02 1.68E-05 1.53E-04 16 371 "TMEM132B,PKP1,GNPTAB,HEATR5A,RABGAP1L,MTX3,DCUN1D2,DLEU1,PAICS,ZNF446,OXGR1,UTP20,GOLGA3,COX18,TMPO,RIMBP2" MicroRNA hsa-miR-371b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.64E-06 4.06E-02 1.73E-05 1.59E-04 16 372 "TMEM132B,PKP1,GNPTAB,HEATR5A,RABGAP1L,MTX3,DCUN1D2,DLEU1,PAICS,ZNF446,OXGR1,UTP20,GOLGA3,COX18,TMPO,RIMBP2" MicroRNA hsa-miR-1913:mirSVR_highEffct hsa-miR-1913:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.95E-06 4.23E-02 1.80E-05 1.65E-04 18 461 "ARHGEF7,TAPT1,ZNF586,DCAF8,EGLN3,RGS4,BORA,SAP18,PCGF3,TOMM40L,FOXO1,CGREF1,LPIN1,C5orf56,AP4S1,RMST,FAM71C,SKA3" MicroRNA hsa-miR-18b-5p:Functional MTI Functional MTI miRTarbase 7.97E-06 4.24E-02 1.81E-05 1.65E-04 9 116 "CAD,PCDH9,PDE4D,DCAF8,KLHL3,SUPT7L,RNF4,CRB1,IGF1" MicroRNA "ATGTTTC,MIR-494:MSigDB" "ATGTTTC,MIR-494:MSigDB" MSigDB 8.16E-06 4.34E-02 1.85E-05 1.69E-04 10 147 "CUL4A,ARHGAP5,NOVA1,PCSK1,SFSWAP,FBXO11,NBEA,PPARGC1A,TMED2,UBE2K" MicroRNA hsa-miR-3193:mirSVR_highEffct hsa-miR-3193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.16E-06 4.34E-02 1.85E-05 1.69E-04 10 147 "CUL4A,FCGR2C,VIT,SNCAIP,ABCA11P,WDCP,ANKLE2,IKBIP,EML4,ZNF26" MicroRNA hsa-miR-3662:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-06 4.43E-02 1.88E-05 1.73E-04 13 253 "MDM4,MYBPC1,SLC5A6,TOGARAM2,NUDT12,G3BP2,RNF219,MARVELD2,CLIP1,BRMS1L,LILRB1,UBE2K,ZDHHC20" MicroRNA hsa-miR-181b-5p:Functional MTI Functional MTI miRTarbase 8.44E-06 4.49E-02 1.91E-05 1.75E-04 16 375 "ULK1,ZNF664,G3BP2,MTX3,RAN,DTD2,LATS2,STX2,DRAM1,FBXO11,MRPS14,ZNF667,ADAM17,RAB2B,HSP90B1,NSD2" MicroRNA "GCAAGGA,MIR-502:MSigDB" "GCAAGGA,MIR-502:MSigDB" MSigDB 8.58E-06 4.57E-02 1.94E-05 1.78E-04 7 64 "MPZL1,RILPL1,NFXL1,KLHL3,RNF31,RIMBP2,GPN1" MicroRNA hsa-miR-609:PITA hsa-miR-609:PITA_TOP PITA 8.58E-06 4.57E-02 1.94E-05 1.78E-04 7 64 "MAP1B,PCCA,KIRREL1,ETF1,CCDC88A,BAZ1A,KLF12" MicroRNA hsa-miR-4789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.66E-06 4.60E-02 1.96E-05 1.79E-04 14 293 "SYT2,ITGBL1,CEP135,ATG10,FGF9,FLT1,BRMS1L,SLC22A4,LILRB1,PPARGC1A,RASSF6,TECRL,NLRP8,ZMYM2" MicroRNA hsa-miR-4282:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.66E-06 4.60E-02 1.96E-05 1.79E-04 14 293 "RALGAPA1,MAP1B,PDE4D,PGGT1B,EIF2AK2,COCH,RAN,PCBD2,FOXO1,SLC8A1,NEDD1,GOLGA3,DCP2,LMNB1" MicroRNA hsa-miR-1538:mirSVR_lowEffct hsa-miR-1538:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.68E-06 4.62E-02 1.96E-05 1.79E-04 18 464 "AACS,NFATC4,CDK18,OCIAD1,NR1H4,LGR6,DHRS2,FNIP1,HSD17B7,TMEM183A,PPARGC1A,STON1,TEP1,TPO,IRF1,ZBED3-AS1,KIT,NUAK2" MicroRNA hsa-miR-1228-3p:Functional MTI Functional MTI miRTarbase 8.68E-06 4.62E-02 1.96E-05 1.79E-04 13 254 "ATP6V1G3,APAF1,PPP1R12B,BCL2L2,RILPL1,FAM129A,TMEM33,DCUN1D2,EIF2B1,ZCCHC8,BRMS1L,ZNF274,NFASC" MicroRNA hsa-miR-485-5p:Non-Functional MTI (Weak) Non-Functional MTI (Weak) miRTarbase 8.74E-06 4.65E-02 1.97E-05 1.81E-04 20 557 "MATN3,MDM4,HOMEZ,PCSK1,UBXN2A,EIF2AK2,ZNF329,DTD2,TBC1D19,ARSK,ZCCHC8,PLEKHA6,SLC30A6,LPIN1,PPARGC1A,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5" MicroRNA hsa-miR-885-3p:mirSVR_highEffct hsa-miR-885-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.19E-06 4.89E-02 2.07E-05 1.90E-04 10 149 "CUL4A,DGKQ,CLIP4,STK32B,BRMS1L,MYO16,KDM3B,LRCH1,ZBTB37,AXDND1" MicroRNA hsa-miR-147b:mirSVR_lowEffct hsa-miR-147b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.40E-06 5.00E-02 2.12E-05 1.94E-04 15 336 "CENPBD1P1,CD84,ARHGEF7,SPATA18,C14orf119,MPHOSPH9,TOMM40L,ATP8A2,PPARGC1A,MAST4,ADAMTS19,NSD2,PGAM5,CHPT1,KIR2DS4" MicroRNA hsa-let-7e*:mirSVR_lowEffct hsa-let-7e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.44E-06 5.02E-02 2.13E-05 1.95E-04 13 256 "RALGAPA1,MDM4,MSH2,STARD13,NOVA1,CDK17,VIT,THAP6,B3GLCT,SH3YL1,VEZT,IQGAP2,ZNF304" MicroRNA hsa-miR-185*:mirSVR_highEffct hsa-miR-185*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.67E-06 5.14E-02 2.18E-05 1.99E-04 21 609 "AP1G2,ADGRD1,CBLN3,PAH,CDK17,ITGBL1,GNPTAB,EGLN3,IPO4,VEZT,PAICS,NR5A2,DCAF11,MEGF10,CMPK2,NFASC,DRC1,STON1,TFDP1,PLB1,KCNJ9" MicroRNA hsa-miR-1228*:mirSVR_lowEffct hsa-miR-1228*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.72E-06 5.17E-02 2.19E-05 2.00E-04 19 514 "KIAA1211,HOMEZ,PPFIA4,MYH6,CENPC,SNCAIP,RNF31,RB1,ZNF329,RGS12,SLC22A17,POLK,SLC34A2,GCKR,ANO4,RAB2B,MZF1,ZFHX2,MFSD2B" MicroRNA hsa-miR-3612:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-05 5.33E-02 2.25E-05 2.06E-04 17 424 "CCNB1,PDGFRA,PIGR,EPGN,NCOR2,MPHOSPH8,SUPT7L,SLC35F6,TMEM33,TCTN2,ARSK,MRPS14,DCAF11,SNRNP35,COX18,ATP6V0A2,GUF1" MicroRNA hsa-miR-891a:mirSVR_lowEffct hsa-miR-891a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-05 5.36E-02 2.27E-05 2.08E-04 15 338 "SEMA6A,CUL4A,GLT1D1,WDFY2,SNX6,NCOR2,ZNF329,RGS4,PCBD2,GOLGA3,FCRLA,CRB1,ZMYM2,CAB39L,LMNB1" MicroRNA hsa-miR-4487:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-05 5.38E-02 2.28E-05 2.08E-04 12 220 "HOMEZ,PPP1R12B,SYT2,CCNB1,GNPTAB,UBXN2A,TMEM33,STX2,FNIP1,MRPS14,NFASC,IGSF8" MicroRNA hsa-miR-4257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-05 5.46E-02 2.31E-05 2.11E-04 16 381 "RILPL1,CCNB1,CEP135,SNX17,SUPT7L,SLC35F6,TMEM33,TXNDC15,LATS2,TBC1D19,MRPS14,SNRNP35,COX18,ATP6V0A2,GUF1,PGAM5" MicroRNA hsa-miR-492:mirSVR_highEffct hsa-miR-492:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-05 5.57E-02 2.35E-05 2.15E-04 14 298 "RALGAPA1,MATN3,AP1G2,POU2F1,PIGG,G3BP2,CLIP4,F10,SUPT20H,GABRA2,GABRB1,NAAA,PSME4,FIP1L1" MicroRNA hsa-miR-4761-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-05 5.57E-02 2.35E-05 2.15E-04 6 44 "MCFD2,TM9SF1,RUBCNL,POTEM,MTUS2,ATP6V0A2" MicroRNA hsa-miR-139-3p:mirSVR_lowEffct hsa-miR-139-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-05 5.81E-02 2.45E-05 2.24E-04 18 472 "FAM193A,ASTN1,SYT2,LDB2,ZNF595,WDFY2,GALNT14,GUSBP3,LRPPRC,STK32B,PCGF3,F7,FLT1,NAAA,KDM3B,NPL,PGAM5,LINC01913" MicroRNA hsa-miR-516a-5p:mirSVR_highEffct hsa-miR-516a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-05 5.88E-02 2.48E-05 2.27E-04 11 186 "MYBPC1,FCRLB,PCCA,SCFD2,PKP1,VCAN,LAP3,ZCCHC8,MAST4,HEXB,GUF1" MicroRNA hsa-miR-6868-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-05 5.88E-02 2.48E-05 2.27E-04 11 186 "RALGAPA1,ABL2,ADD1,RGS5,PPP1R3E,ATP6AP1L,POTEM,CD244,STRN,HMGCR,PABPN1" MicroRNA hsa-miR-487b:mirSVR_lowEffct hsa-miR-487b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.13E-05 6.00E-02 2.53E-05 2.32E-04 14 300 "AACS,GLT1D1,CCDC122,BOD1L1,HOMER1,FCRL5,FAM129A,SMC6,FGF9,NPAS3,SRP72,ARHGAP30,NSD2,LHX9" MicroRNA hsa-miR-505-3p:Functional MTI Functional MTI miRTarbase 1.16E-05 6.17E-02 2.60E-05 2.38E-04 12 223 "TMEM132B,MCFD2,MYBPC1,DHX9,REST,TRIM28,ELK3,TM9SF1,PAICS,THADA,YTHDC2,IGF1" MicroRNA hsa-miR-193a-5p:PITA hsa-miR-193a-5p:PITA_TOP PITA 1.19E-05 6.34E-02 2.67E-05 2.44E-04 8 93 "SFTA3,CUL4A,NOVA1,DCLK1,RGS4,KDM3B,ANO4,XPO4" MicroRNA hsa-miR-892a:PITA hsa-miR-892a:PITA_TOP PITA 1.21E-05 6.42E-02 2.70E-05 2.48E-04 13 262 "CAST,FCHO2,CDK17,CHD1,ZNF595,ATAD2B,BOD1L1,HOMER1,AKAP6,NTN4,SLC8A1,KDM3B,KCNT2" MicroRNA hsa-miR-3606-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-05 6.51E-02 2.74E-05 2.51E-04 11 188 "MCFD2,ASCL1,XPR1,NUP37,NGDN,EIF2AK2,SLC8A1,NEDD1,ZBTB37,TFDP1,LMNB1" MicroRNA hsa-miR-375:Functional MTI Functional MTI miRTarbase 1.26E-05 6.68E-02 2.81E-05 2.57E-04 18 477 "XPR1,CFL2,BOD1L1,EIF2AK2,WDR1,PPP2R3C,SDC1,VEZT,G2E3,GFM2,CCDC88A,PSME4,KMT5A,BAZ1A,TENT2,ZFHX2,ZNF470,CHPT1" MicroRNA hsa-miR-6843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-05 6.74E-02 2.83E-05 2.59E-04 12 225 "ABL2,TMEM132B,HEATR5A,RABGAP1L,SLC35F6,SBNO1,DCUN1D2,TLR6,PCBD2,ZCCHC8,ZNF446,ERBIN" MicroRNA "AACTGGA,MIR-145:MSigDB" "AACTGGA,MIR-145:MSigDB" MSigDB 1.27E-05 6.74E-02 2.83E-05 2.59E-04 12 225 "SEMA6A,SLC4A4,CFL2,MTX3,RNF31,RASA1,NDUFAF7,FOXO1,IVNS1ABP,TENT2,SELENOI,LOX" MicroRNA hsa-miR-6848-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-05 6.74E-02 2.83E-05 2.59E-04 12 225 "ABL2,TMEM132B,HEATR5A,RABGAP1L,SLC35F6,SBNO1,DCUN1D2,TLR6,PCBD2,ZCCHC8,ZNF446,ERBIN" MicroRNA hsa-miR-326:PITA hsa-miR-326:PITA_TOP PITA 1.29E-05 6.84E-02 2.87E-05 2.63E-04 11 189 "RALGAPA1,MAP1B,BCL2L2,NEDD8,ATAD2B,CSNK1G3,CEP350,F11R,NR5A2,KDM3B,ERBIN" MicroRNA hsa-miR-330-5p:PITA hsa-miR-330-5p:PITA_TOP PITA 1.29E-05 6.84E-02 2.87E-05 2.63E-04 11 189 "RALGAPA1,MAP1B,BCL2L2,NEDD8,ATAD2B,CSNK1G3,CEP350,F11R,NR5A2,KDM3B,ERBIN" MicroRNA hsa-miR-4253:mirSVR_highEffct hsa-miR-4253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-05 6.87E-02 2.88E-05 2.64E-04 18 478 "MDM4,KIAA1211,ATP1A2,NRL,SLC5A8,PREPL,CEP135,G3BP2,FAM129A,TOMM40L,GORAB,TM9SF1,RUBCNL,DCAF11,UHRF1BP1L,ANO4,RAB2B,RMST" MicroRNA hsa-miR-6785-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-05 6.97E-02 2.92E-05 2.67E-04 25 825 "MATN3,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-6883-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-05 6.97E-02 2.92E-05 2.67E-04 25 825 "MATN3,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-574-3p:mirSVR_lowEffct hsa-miR-574-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-05 7.06E-02 2.96E-05 2.71E-04 15 346 "TAPT1,VCAN,LRPPRC,DCUN1D2,LGR6,PIBF1,POLK,SUCO,LRCH1,MAST4,ZNF544,UBE2K,HPCAL1,NSD2,CCDC169" MicroRNA hsa-miR-297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-05 7.18E-02 3.01E-05 2.75E-04 11 190 "TMEM132B,RGS5,CFL2,DCAF8,MBNL2,CCDC38,NT5C1B,TECRL,IGF1,ZFHX2,NT5C1B-RDH14" MicroRNA hsa-miR-29a-3p:Functional MTI Functional MTI miRTarbase 1.36E-05 7.25E-02 3.03E-05 2.78E-04 13 265 "SNX24,FAM193A,GAS2L3,DNMT3A,RAN,REST,RNASEL,KDM5B,KMT5C,TDG,HMGCR,IGF1,LOX" MicroRNA hsa-miR-6506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.28E-02 3.05E-05 2.79E-04 16 390 "BCL2L2,PIK3C2B,THAP6,C12orf65,CEP135,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,SBNO1,PCGF3,N4BP2L2,ZNF446,GTF2H3,TXK,SELENOI" MicroRNA hsa-miR-583:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-05 7.30E-02 3.05E-05 2.80E-04 10 156 "NEDD8,PIGR,AKAP6,POU2F1,SLC35F6,TMEM33,KLHL12,CCDC88A,STRN,HAL" MicroRNA hsa-miR-384:PITA hsa-miR-384:PITA_TOP PITA 1.37E-05 7.30E-02 3.05E-05 2.80E-04 10 156 "ZNF664,PDE4D,STRN3,MBNL2,CLIP1,FBXO11,SLC8A1,ERBIN,METAP2,SLAIN1" MicroRNA hsa-miR-873-5p.1:TargetScan hsa-miR-873-5p.1 TargetScan 1.42E-05 7.54E-02 3.15E-05 2.89E-04 13 266 "APC,PPP1R3E,CAD,PDE4D,MATR3,PIGG,EGLN3,RASA1,ARGLU1,GABRB1,ERAP1,GRSF1,HMGCR" MicroRNA hsa-miR-216a-5p:TargetScan hsa-miR-216a-5p TargetScan 1.48E-05 7.84E-02 3.28E-05 3.00E-04 13 267 "MCC,CUL4A,NCOA1,BOD1L1,KLHL3,F11R,MEMO1,ETF1,N4BP2,NR5A2,KIF21B,MSH6,KLF12" MicroRNA hsa-miR-539:PITA hsa-miR-539:PITA_TOP PITA 1.48E-05 7.89E-02 3.30E-05 3.02E-04 18 483 "MAP1B,NCOA1,CFL2,GPR180,PITX1,HOMER1,COPA,KLHL3,COCH,PARPBP,RASA1,TMEM33,POLR1D,ETF1,FNIP1,PPARGC1A,KLF12,UBE2K" MicroRNA hsa-miR-489:PITA hsa-miR-489:PITA_TOP PITA 1.49E-05 7.92E-02 3.31E-05 3.03E-04 11 192 "SEMA6A,NCOA1,B4GALT3,PKP1,CLOCK,G3BP2,RAN,EFNA5,PDS5B,SPTSSA,KCNN2" MicroRNA hsa-miR-711:mirSVR_highEffct hsa-miR-711:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-05 7.99E-02 3.33E-05 3.05E-04 16 393 "COG6,RGS5,NOVA1,CDKL2,PCK2,GNPTAB,PIGG,RB1,AASDH,LAP3,EIF2B1,GP6,TADA1,MAST4,MZF1,KCNN2" MicroRNA hsa-miR-6716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-05 8.01E-02 3.34E-05 3.06E-04 8 96 "MCC,UHMK1,RUBCNL,NMNAT2,MRPS27,ZBTB37,KMT5A,UBC" MicroRNA hsa-miR-4327:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-05 8.01E-02 3.34E-05 3.06E-04 8 96 "HOMEZ,SLC5A6,ZNF664,MPHOSPH8,FCRL2,PAICS,POTEM,NFASC" MicroRNA hsa-miR-448:PITA hsa-miR-448:PITA_TOP PITA 1.52E-05 8.08E-02 3.37E-05 3.08E-04 17 438 "ADD1,NCOA1,ATP2B4,PCDH9,PDE4D,ATAD2B,HOMER1,DMXL1,MBNL2,TBC1D19,NBEA,SLC12A2,MYT1L,ATP11A,DOCK9,XPO4,RAB2B" MicroRNA hsa-miR-152-3p:Functional MTI Functional MTI miRTarbase 1.54E-05 8.16E-02 3.40E-05 3.11E-04 10 158 "MCFD2,STARD13,CLOCK,RNF219,FGFR3,TACC3,MRPS27,ADAM17,HSP90B1,TENT2" MicroRNA hsa-miR-5695:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-05 8.28E-02 3.45E-05 3.16E-04 9 126 "CDK18,POU2F1,HEATR5A,FAM129A,MPHOSPH9,PCBD2,KDM3B,NFASC,ADAM17" MicroRNA hsa-miR-337-3p:PITA hsa-miR-337-3p:PITA_TOP PITA 1.56E-05 8.31E-02 3.46E-05 3.17E-04 11 193 "MAP1B,FCHO2,PIK3C2B,ATAD2B,PARPBP,RB1,EFNA5,ELF1,CCDC88A,PPIP5K2,TENT2" MicroRNA hsa-miR-149-3p:Functional MTI Functional MTI miRTarbase 1.57E-05 8.34E-02 3.47E-05 3.18E-04 25 834 "MATN3,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-618:PITA hsa-miR-618:PITA_TOP PITA 1.60E-05 8.49E-02 3.53E-05 3.23E-04 13 269 "KCTD12,FGFRL1,NOVA1,ZNF664,ATAD2B,HOMER1,RCHY1,GNPTAB,WDR1,ELF1,FGFR3,GJA3,KLF12" MicroRNA hsa-miR-628-5p:PITA hsa-miR-628-5p:PITA_TOP PITA 1.62E-05 8.62E-02 3.58E-05 3.28E-04 10 159 "BIRC6,DDX59,G3BP2,NBEA,BRMS1L,TMED2,MTUS2,UBE2K,HMGCR,TMEM178A" MicroRNA hsa-miR-302a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-05 8.82E-02 3.67E-05 3.36E-04 9 127 "NRXN1,SACS,G3BP2,REST,UTP15,SUCO,ARHGEF28,ATP6V0A2,IGF1" MicroRNA hsa-miR-1290:PITA hsa-miR-1290:PITA_TOP PITA 1.68E-05 8.92E-02 3.71E-05 3.39E-04 15 353 "SEMA6A,CUL4A,ARHGAP5,FCHO2,NRXN1,HECTD1,LRRTM2,MBNL2,CCDC88A,LRCH1,NMU,GRSF1,UBE2K,SLAIN1,SPTSSA" MicroRNA hsa-miR-4728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-05 9.03E-02 3.75E-05 3.43E-04 25 838 "MATN3,PPP1R12B,PDGFRA,PIGR,NCOR2,BRI3BP,UBXN2A,SUPT7L,SLC35F6,ZNF329,DTD2,TCTN2,TBC1D19,ARSK,ZCCHC8,POTEM,ZBTB37,GOLGA3,COX18,RAB2B,IGSF8,IGF1,ZNF324B,PGAM5,FAM151B" MicroRNA hsa-miR-579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-05 9.10E-02 3.78E-05 3.46E-04 10 160 "KIAA1211,ITGBL1,SMIM14,DMXL1,RAN,RNASEL,TRAPPC13,SLC30A6,DCP2,SELENOI" MicroRNA hsa-miR-937:mirSVR_lowEffct hsa-miR-937:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-05 9.10E-02 3.78E-05 3.46E-04 10 160 "SNTG2,WDFY2,WDR1,PACRGL,ARL6IP4,FCGR3A,TOMM40L,FCGR3B,TPO,TMEM178A" MicroRNA "ATGTTAA,MIR-302C:MSigDB" "ATGTTAA,MIR-302C:MSigDB" MSigDB 1.72E-05 9.14E-02 3.79E-05 3.47E-04 12 232 "FCHO2,PCDH9,PDE4D,MATR3,TMEM33,FOXG1,VEZT,GABRA2,PPARGC1A,STRN,ADGRL3,FAM49A" MicroRNA hsa-let-7d*:mirSVR_highEffct hsa-let-7d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-05 9.15E-02 3.79E-05 3.47E-04 11 195 "CDKL4,RGSL1,AKAP6,MBNL2,KLHL12,ZCCHC8,UFM1,SNRPF,TMPO,HMGCR,KCNT2" MicroRNA hsa-miR-223-3p:Functional MTI Functional MTI miRTarbase 1.75E-05 9.31E-02 3.86E-05 3.53E-04 8 98 "SNX24,SCARB1,LATS2,FOXO1,POTEM,NMNAT2,HSP90B1,IL6ST" MicroRNA hsa-miR-938:PITA hsa-miR-938:PITA_TOP PITA 1.75E-05 9.31E-02 3.86E-05 3.53E-04 8 98 "APAF1,MPZL1,RCHY1,SACS,IVNS1ABP,HSPH1,KIF2A,KIF3C" MicroRNA hsa-miR-95-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-05 9.39E-02 3.89E-05 3.56E-04 9 128 "WDR35,AASDH,TLR6,SUCO,LIMCH1,COMMD6,METAP2,DCP2,LMLN" MicroRNA hsa-miR-2909:mirSVR_highEffct hsa-miR-2909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-05 9.60E-02 3.97E-05 3.64E-04 17 444 "RALGAPA1,KIAA1211,COG6,HOMEZ,KCTD12,PDGFRA,KLHL3,CLIP4,RUBCNL,GFM2,IVNS1ABP,MYO16,GABRA2,RASSF6,ARHGAP30,HTR2A,ZNF26" MicroRNA hsa-miR-3919:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-05 9.61E-02 3.97E-05 3.64E-04 10 161 "ARHGEF7,NUP37,POU2F1,G3BP2,ATG10,RNASEL,TRIM28,ATP8A2,HSP90B1,LMNB1" MicroRNA hsa-miR-378a-3p:TargetScan hsa-miR-378a-3p TargetScan 1.81E-05 9.61E-02 3.97E-05 3.64E-04 10 161 "BCL2L2,NFKBIA,FCRLB,CHIT1,REST,FOXG1,GRSF1,IGF1,IL6ST,KIF2A" MicroRNA hsa-miR-4327:mirSVR_highEffct hsa-miR-4327:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-05 9.85E-02 4.07E-05 3.73E-04 20 587 "APC,DAOA,FAM177A1,WDFY2,BOD1L1,CLIP4,CWC27,ABCA11P,ADGRV1,PCGF3,TRAPPC13,UTP15,SCYL2,IVNS1ABP,CMPK2,STRN,RIMBP2,UBE2K,MZF1,KCNN2" MicroRNA hsa-miR-1193:TargetScan hsa-miR-1193 TargetScan 1.87E-05 9.96E-02 4.11E-05 3.77E-04 12 234 "NLN,ATP1A2,NOVA1,ODC1,NUP37,MATR3,EFNA5,MZB1,PCBD2,BRMS1L,KIF21B,IGF1" MicroRNA hsa-miR-5100:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-05 1.00E-01 4.13E-05 3.78E-04 7 72 "PCSK1,WDFY2,MATR3,SUCO,UFM1,ZBTB49,SPATA13" MicroRNA "ATAGGAA,MIR-202:MSigDB" "ATAGGAA,MIR-202:MSigDB" MSigDB 1.89E-05 1.00E-01 4.14E-05 3.79E-04 8 99 "ATP2B4,RASA1,ELF1,SUCO,CCDC88A,ERBIN,KLF12,UBE2K" MicroRNA hsa-miR-3160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-05 1.01E-01 4.15E-05 3.80E-04 11 197 "HOMEZ,PPP1R12B,CCNB1,GNPTAB,UBXN2A,NOS1AP,TMEM33,STX2,FNIP1,MRPS14,SKA3" MicroRNA "TTTGCAG,MIR-518A-2:MSigDB" "TTTGCAG,MIR-518A-2:MSigDB" MSigDB 1.89E-05 1.01E-01 4.15E-05 3.80E-04 11 197 "NEDD8,NOVA1,HECTD1,FBXL5,ETF1,IVNS1ABP,KDM5B,ATP11A,NUAK2,CDK2AP1,PABPN1" MicroRNA hsa-miR-664b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-05 1.01E-01 4.18E-05 3.83E-04 10 162 "KIAA1211,ITGBL1,SMIM14,DMXL1,RAN,RNASEL,TRAPPC13,SLC30A6,DCP2,SELENOI" MicroRNA hsa-miR-518d-3p:mirSVR_lowEffct hsa-miR-518d-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-05 1.05E-01 4.32E-05 3.95E-04 19 541 "SFTA3,LRRC43,ARHGAP5,PFKFB2,NRXN1,TAPT1,ZNF586,SNX17,MEMO1,MARVELD2,N4BP2L2,FLT1,MCCC2,MAST4,RNF212,RIMBP2,ADAMTS19,KLF12,RMST" MicroRNA hsa-miR-4693-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-05 1.05E-01 4.33E-05 3.97E-04 6 49 "FAM163A,LRRTM2,RB1,REST,MSH6,AP4S1" MicroRNA hsa-miR-196a:PITA hsa-miR-196a:PITA_TOP PITA 1.98E-05 1.06E-01 4.34E-05 3.97E-04 11 198 "BIRC6,PDGFRA,CEP350,TMEM161B,NTN4,MBNL2,FNIP1,FOXO1,ACSL6,SPTSSA,PABPN1" MicroRNA hsa-miR-196b:PITA hsa-miR-196b:PITA_TOP PITA 1.98E-05 1.06E-01 4.34E-05 3.97E-04 11 198 "BIRC6,PDGFRA,CEP350,TMEM161B,NTN4,MBNL2,FNIP1,FOXO1,ACSL6,SPTSSA,PABPN1" MicroRNA hsa-miR-552-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-05 1.06E-01 4.37E-05 4.01E-04 9 130 "SNX24,FCHO2,CLOCK,VCAN,RAN,TMEM33,ETF1,GABRB1,EML4" MicroRNA hsa-miR-517b:mirSVR_highEffct hsa-miR-517b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-05 1.07E-01 4.39E-05 4.02E-04 10 163 "ZMYM5,NRXN1,C12orf65,DNM3,MATR3,NDUFAF7,SGCG,EFR3B,NPHS2,CDK2AP1" MicroRNA hsa-miR-1248:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-05 1.07E-01 4.39E-05 4.02E-04 10 163 "RALGAPA1,ABL2,ADD1,RGS5,PPP1R3E,UGT2B28,ATP6AP1L,POTEM,LMNB1,PABPN1" MicroRNA hsa-miR-566:mirSVR_lowEffct hsa-miR-566:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-05 1.07E-01 4.39E-05 4.02E-04 14 316 "CADM3,DAOA,CDK18,PDE4D,LRRTM2,DCUN1D2,LGR6,PCGF3,SUPT20H,ERAP1,CNTN2,TPO,ZNF324B,LHX9" MicroRNA hsa-miR-328:mirSVR_highEffct hsa-miR-328:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-05 1.09E-01 4.45E-05 4.08E-04 16 403 "FAM193A,CD1D,PDGFRA,DDX59,TSEN15,NR1I3,DNMT3A,OGFOD2,DTD2,RGS4,ELF1,F10,TNR,IL6ST,KIF2A,RNASE11" MicroRNA hsa-miR-185-5p:Functional MTI Functional MTI miRTarbase 2.04E-05 1.09E-01 4.45E-05 4.08E-04 15 359 "CAMK4,SYT2,SCARB1,UHMK1,POU2F1,MATR3,COCH,FAM228A,MZB1,GOLGA2P5,TM9SF1,SLC8A1,CCDC88A,TFDP1,SLC7A8" MicroRNA hsa-miR-548ap-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548y:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548o-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548au-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ar-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548as-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548aq-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548am-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ak:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ad-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ay-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548bb-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548w:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ae-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548ab:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.11E-01 4.50E-05 4.12E-04 11 199 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-4294:mirSVR_highEffct hsa-miR-4294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-05 1.11E-01 4.52E-05 4.14E-04 20 592 "BLZF1,NFATC4,SCFD2,ZNF595,FAM163A,RCHY1,HEATR5A,LRRTM2,UBXN2A,CEP350,PARPBP,EIF2D,DRAM1,ADGRV1,TNFRSF19,GABRA2,FAM114A1,OXGR1,KDM3B,TMPO" MicroRNA hsa-miR-95:mirSVR_lowEffct hsa-miR-95:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-05 1.12E-01 4.56E-05 4.18E-04 15 360 "WDR35,EP400,SLC25A3,TINF2,LATS2,MBNL2,LGR6,TM9SF1,RUBCNL,UGGT2,LIMCH1,MCCC2,EML4,AP4S1,NSD2" MicroRNA hsa-miR-130a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.13E-01 4.60E-05 4.21E-04 9 131 "MAP1B,MCFD2,TLR6,FNIP1,ERBIN,ADAM17,ZNF550,DCP2,LMNB1" MicroRNA hsa-miR-524-3p:mirSVR_lowEffct hsa-miR-524-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-05 1.15E-01 4.69E-05 4.29E-04 16 405 "PITPNM2,NRL,SCARB1,CDK18,THTPA,EPGN,FAM228A,TOMM40L,SUCO,ZNF274,SRP72,EML4,TFDP1,ZBTB49,TADA2B,IRF1" MicroRNA hsa-miR-196b-5p:TargetScan hsa-miR-196b-5p TargetScan 2.17E-05 1.15E-01 4.69E-05 4.29E-04 13 277 "ABL2,BIRC6,PDGFRA,NRXN1,CEP350,NOP9,PACRGL,MBNL2,FNIP1,POTEM,ACSL6,RXFP2,IGF1" MicroRNA hsa-miR-196a-5p:TargetScan hsa-miR-196a-5p TargetScan 2.17E-05 1.15E-01 4.69E-05 4.29E-04 13 277 "ABL2,BIRC6,PDGFRA,NRXN1,CEP350,NOP9,PACRGL,MBNL2,FNIP1,POTEM,ACSL6,RXFP2,IGF1" MicroRNA hsa-miR-548j-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-05 1.16E-01 4.70E-05 4.31E-04 11 200 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-3151:mirSVR_highEffct hsa-miR-3151:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-05 1.16E-01 4.70E-05 4.31E-04 19 545 "CD1E,PCK2,CPNE6,TINF2,RNF219,ATG10,ARGLU1,OGFOD2,KIRREL1,KLHL12,STK32B,FCAR,FLT3,VEZT,NAAA,AP4S1,RAB2B,SDR39U1,PABPN1" MicroRNA "TGAGATT,MIR-216:MSigDB" "TGAGATT,MIR-216:MSigDB" MSigDB 2.18E-05 1.16E-01 4.71E-05 4.32E-04 8 101 "NCOA1,PCCA,DCLK1,MATR3,MBNL2,ETF1,ADGRL3,EML4" MicroRNA hsa-miR-548ah-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-05 1.19E-01 4.82E-05 4.41E-04 14 319 "MDM4,ULK1,THAP6,POU2F1,BRI3BP,UBXN2A,DCAF8,FBXL5,EGLN3,FAM129A,REST,MEMO1,G2E3,ZBTB37" MicroRNA hsa-miR-6513-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-05 1.19E-01 4.82E-05 4.41E-04 10 165 "ABL2,KCTD12,ZNF664,FAM177A1,RABGAP1L,ETF1,TLR6,PCBD2,PAICS,ZNF84" MicroRNA hsa-miR-23c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-05 1.20E-01 4.87E-05 4.46E-04 9 132 "MAP1B,MCFD2,TLR6,FNIP1,ERBIN,ADAM17,ZNF550,DCP2,LMNB1" MicroRNA hsa-miR-296-5p:mirSVR_lowEffct hsa-miR-296-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.30E-05 1.22E-01 4.96E-05 4.54E-04 28 1017 "KIAA1211,UVSSA,AACS,KCTD12,CACNA1E,CAD,LDB2,GLT1D1,CHD1,PIK3C2B,TOGARAM2,F11R,EMC9,RNF4,ZNF219,NDUFAF7,SPON2,FGFR3,FTLP10,IVNS1ABP,KIF21B,RBKS,GCKR,NSD2,IRF1,MFSD2B,LINC01913,NUAK2" MicroRNA hsa-miR-125b:PITA hsa-miR-125b:PITA_TOP PITA 2.31E-05 1.23E-01 4.97E-05 4.55E-04 14 320 "ABL2,HOMEZ,SLC4A4,STARD13,CHAMP1,SCARB1,NCOR2,TMEM161B,TBC1D1,KMT5C,KHNYN,GRSF1,NPL,HMGCR" MicroRNA hsa-miR-125a-5p:PITA hsa-miR-125a-5p:PITA_TOP PITA 2.31E-05 1.23E-01 4.97E-05 4.55E-04 14 320 "ABL2,HOMEZ,SLC4A4,STARD13,CHAMP1,SCARB1,NCOR2,TMEM161B,TBC1D1,KMT5C,KHNYN,GRSF1,NPL,HMGCR" MicroRNA hsa-miR-485-3p:TargetScan hsa-miR-485-3p TargetScan 2.31E-05 1.23E-01 4.97E-05 4.55E-04 14 320 "NLN,APBB2,PDE4D,GPR180,NRXN1,BOD1L1,MEMO1,PCGF3,FLT1,KIF21B,PPARGC1A,ADAM17,IL6ST,ANKS1B" MicroRNA hsa-miR-3609:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-05 1.23E-01 4.97E-05 4.55E-04 14 320 "MDM4,ULK1,THAP6,POU2F1,BRI3BP,UBXN2A,DCAF8,FBXL5,EGLN3,FAM129A,REST,MEMO1,G2E3,ZBTB37" MicroRNA hsa-miR-539-3p:TargetScan hsa-miR-539-3p TargetScan 2.31E-05 1.23E-01 4.97E-05 4.55E-04 14 320 "NLN,APBB2,PDE4D,GPR180,NRXN1,BOD1L1,MEMO1,PCGF3,FLT1,KIF21B,PPARGC1A,ADAM17,IL6ST,ANKS1B" MicroRNA hsa-miR-4649-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-05 1.25E-01 5.04E-05 4.62E-04 8 102 "CCNB1,PIGR,PCBD2,PAICS,MRPS27,SRP54,GUF1,UBC" MicroRNA hsa-miR-548d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-05 1.27E-01 5.12E-05 4.69E-04 11 202 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-548i:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-05 1.27E-01 5.12E-05 4.69E-04 11 202 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA "CTATGCA,MIR-153:MSigDB" "CTATGCA,MIR-153:MSigDB" MSigDB 2.39E-05 1.27E-01 5.12E-05 4.69E-04 11 202 "APC,ARHGAP5,SLC4A4,AKAP6,ITSN2,KLHL3,RASA1,TBC1D19,FOXO1,PPARGC1A,DCP2" MicroRNA hsa-miR-376a-3p:TargetScan hsa-miR-376a-3p TargetScan 2.39E-05 1.27E-01 5.12E-05 4.69E-04 11 202 "PITPNM2,GPR180,PRKD1,RASA1,ELF1,ELOVL7,POLK,FBXO11,PCDH17,KLF12,PGAM5" MicroRNA hsa-miR-376b-3p:TargetScan hsa-miR-376b-3p TargetScan 2.39E-05 1.27E-01 5.12E-05 4.69E-04 11 202 "PITPNM2,GPR180,PRKD1,RASA1,ELF1,ELOVL7,POLK,FBXO11,PCDH17,KLF12,PGAM5" MicroRNA hsa-miR-939:mirSVR_highEffct hsa-miR-939:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.47E-05 1.31E-01 5.29E-05 4.84E-04 18 502 "BCL2L2,NGDN,DCAF8,NUDT12,CLIP1,PEAR1,FBXO11,MRPS14,NR5A2,JPH4,NAAA,UHRF1BP1L,LPIN1,TEP1,TGM1,ARHGAP30,TPTE2,ZFHX2" MicroRNA hsa-miR-190b:TargetScan hsa-miR-190b TargetScan 2.48E-05 1.32E-01 5.31E-05 4.86E-04 10 167 "MAP1B,DCLK1,CLOCK,SBNO1,NBEA,GABRB1,NFASC,PCDH17,IGF1,KIF2A" MicroRNA hsa-miR-660:PITA hsa-miR-660:PITA_TOP PITA 2.48E-05 1.32E-01 5.31E-05 4.86E-04 10 167 "PPP1R12B,PCDH9,G3BP2,RNF219,ETF1,SDC1,NBEA,PPARGC1A,GTF3C2,SPTSSA" MicroRNA hsa-miR-190a-5p:TargetScan hsa-miR-190a-5p TargetScan 2.48E-05 1.32E-01 5.31E-05 4.86E-04 10 167 "MAP1B,DCLK1,CLOCK,SBNO1,NBEA,GABRB1,NFASC,PCDH17,IGF1,KIF2A" MicroRNA "ATATGCA,MIR-448:MSigDB" "ATATGCA,MIR-448:MSigDB" MSigDB 2.50E-05 1.33E-01 5.35E-05 4.90E-04 11 203 "ADD1,APBB2,PCDH9,DNM3,TSEN15,MBNL2,NBEA,PLEKHA6,ATP11A,DOCK9,RAB2B" MicroRNA hsa-miR-890:PITA hsa-miR-890:PITA_TOP PITA 2.50E-05 1.33E-01 5.36E-05 4.91E-04 12 241 "RALGAPA1,ARHGAP5,NCOA1,PPP1R12B,BOD1L1,THAP6,LRRTM2,MATR3,NR5A2,EML4,BAZ1A,NSD2" MicroRNA hsa-miR-6729-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-05 1.34E-01 5.39E-05 4.93E-04 8 103 "CCNB1,PIGR,PCBD2,PAICS,MRPS27,SRP54,GUF1,UBC" MicroRNA "AACATTC,MIR-409-3P:MSigDB" "AACATTC,MIR-409-3P:MSigDB" MSigDB 2.55E-05 1.35E-01 5.44E-05 4.98E-04 9 134 "KCTD12,PCDH9,CDK17,CLOCK,MATR3,GNPDA2,MTX3,IVNS1ABP,IGF1" MicroRNA hsa-miR-569:PITA hsa-miR-569:PITA_TOP PITA 2.61E-05 1.39E-01 5.57E-05 5.10E-04 12 242 "SEMA6A,APAF1,NOVA1,PDE4D,PDGFRA,G3BP2,NFASC,PCDH17,ATP11A,PPIP5K2,LMNB1,CDK2AP1" MicroRNA hsa-miR-505:PITA hsa-miR-505:PITA_TOP PITA 2.61E-05 1.39E-01 5.57E-05 5.10E-04 12 242 "ANKRD34B,WDR19,ARHGEF7,NOVA1,ELK3,FAM172A,MAEA,ALKAL2,MYT1L,PPARGC1A,ADGRL3,KIT" MicroRNA hsa-miR-559:Functional MTI Functional MTI miRTarbase 2.61E-05 1.39E-01 5.58E-05 5.11E-04 11 204 "MCC,SMIM15,CDKL2,MPZL1,CCNB1,UHMK1,CEP120,EFNA5,CLIP1,ZBTB37,IL6ST" MicroRNA hsa-miR-6790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.61E-05 1.39E-01 5.58E-05 5.11E-04 13 282 "ABL2,PIGG,SLC35F6,DCUN1D2,DLEU1,TLR6,PCBD2,ZCCHC8,NUBPL,PAICS,DCP2,ZNF84,IRF1" MicroRNA hsa-miR-1468:mirSVR_highEffct hsa-miR-1468:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-05 1.40E-01 5.61E-05 5.14E-04 15 367 "CFL2,JAKMIP1,UBXN2A,NTN4,PACRGL,MBNL2,SAP18,TMEM183A,LRCH1,COMMD6,C1QTNF9B,YIPF7,PLB1,TTC41P,ZDHHC20" MicroRNA hsa-miR-874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.69E-05 1.43E-01 5.73E-05 5.25E-04 7 76 "SNX24,KCTD12,BCL2L2,CAD,SYT2,IVNS1ABP,LTB4R2" MicroRNA hsa-miR-1236-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-05 1.44E-01 5.79E-05 5.30E-04 12 243 "MYBPC1,PPP1R3E,PIGR,SMIM14,PIK3C2B,UBXN2A,ATP6AP1L,TMEM156,TMEM175,LIMCH1,CENPJ,TMEM174" MicroRNA hsa-miR-651:PITA hsa-miR-651:PITA_TOP PITA 2.74E-05 1.46E-01 5.85E-05 5.36E-04 10 169 "RALGAPA1,SEMA6A,ASCL1,SLC4A4,LRRTM2,MEMO1,EFNA5,SUCO,HSPH1,IGF1" MicroRNA hsa-miR-3913-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.49E-01 5.97E-05 5.46E-04 15 369 "MATN3,MDM4,PIGR,CLOCK,ZNF329,TMEM33,TBC1D19,ARSK,ZCCHC8,GOLGA3,COX18,IGF1,ZNF324B,FAM151B,ZDHHC20" MicroRNA hsa-miR-128:PITA hsa-miR-128:PITA_TOP PITA 2.80E-05 1.49E-01 5.98E-05 5.47E-04 18 507 "RALGAPA1,ULK1,PITPNM2,FAM177A1,XPR1,HECTD1,PRKD1,SREK1,RNF219,TMEM161B,FAM172A,CCDC92,CCDC88A,SRP72,PPARGC1A,DCP2,IGF1,LMNB1" MicroRNA hsa-miR-7856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.86E-05 1.52E-01 6.09E-05 5.58E-04 9 136 "NLN,CAD,CD1D,MPHOSPH8,GORAB,MYT1L,PSME4,GOLGA3,CRB1" MicroRNA hsa-miR-3122:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-05 1.54E-01 6.15E-05 5.63E-04 15 370 "MATN3,MDM4,PIGR,CLOCK,ZNF329,TMEM33,TBC1D19,ARSK,ZCCHC8,GOLGA3,COX18,IGF1,ZNF324B,FAM151B,ZDHHC20" MicroRNA hsa-miR-941:mirSVR_highEffct hsa-miR-941:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.89E-05 1.54E-01 6.16E-05 5.64E-04 8 105 "ANKRD34B,HEATR5A,NDUFAF7,PPIP5K2,CRB1,TXK,NSD2,IFT88" MicroRNA hsa-miR-1308:PITA hsa-miR-1308:PITA_TOP PITA 2.89E-05 1.54E-01 6.16E-05 5.64E-04 8 105 "GPR180,ATAD2B,MEMO1,ETF1,PPARGC1A,METAP2,XPO4,KLF12" MicroRNA hsa-miR-1291:mirSVR_highEffct hsa-miR-1291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.98E-05 1.58E-01 6.33E-05 5.80E-04 15 371 "CD84,RILPL1,CD1E,SPATA18,DMXL1,LOC439933,DNMT3A,LGR6,ZNF219,G2E3,TMEM132D,SLC22A4,MAST4,INSM2,ARHGAP30" MicroRNA hsa-miR-513a-5p:Functional MTI Functional MTI miRTarbase 2.99E-05 1.59E-01 6.35E-05 5.81E-04 11 207 "MAP1B,ADD1,KCTD12,UHMK1,ITSN2,TOMM40L,SUCO,NLRP2,WDCP,MRPS14,SPATA13" MicroRNA hsa-miR-3189:mirSVR_highEffct hsa-miR-3189:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.03E-05 1.61E-01 6.43E-05 5.89E-04 18 510 "AMDHD1,LDB2,PAH,CFL2,GPR180,THAP6,EPGN,KIAA0040,ZFYVE16,BIVM,ETF1,PAICS,SRP72,EML4,GZMH,GALP,ANKS1B,IFT88" MicroRNA hsa-miR-216b-5p:Functional MTI Functional MTI miRTarbase 3.03E-05 1.61E-01 6.44E-05 5.90E-04 9 137 "APAF1,CD84,UGT2B28,UBXN2A,OXGR1,KLF12,GUF1,UGT2B7,ZNF324B" MicroRNA hsa-miR-4294:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-05 1.61E-01 6.44E-05 5.90E-04 10 171 "ABL2,APAF1,PIWIL1,STRN3,HEATR5A,SLC35F6,NUBPL,ZBTB37,LPIN1,LINC01551" MicroRNA hsa-miR-10a-5p:Functional MTI Functional MTI miRTarbase 3.06E-05 1.63E-01 6.49E-05 5.94E-04 17 463 "ATP1A2,NUP37,COPA,NCOR2,MTX3,ZNF329,TRAPPC12,ARSK,ADGRV1,ELOVL7,PAICS,MRPS14,CHFR,NCSTN,GTF3C2,CAB39L,TTC7A" MicroRNA hsa-miR-6507-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-05 1.65E-01 6.57E-05 6.02E-04 8 106 "NLN,SEMA6A,WDR66,PIK3C2B,DCAF8,LTB4R2,GUF1,IL6ST" MicroRNA hsa-miR-1180:mirSVR_lowEffct hsa-miR-1180:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-05 1.65E-01 6.59E-05 6.03E-04 18 511 "MDM4,AP1G2,THAP6,MPHOSPH8,TINF2,WDR1,MAEA,ARL6IP4,POLK,JPH4,RAPGEF6,ZBTB37,MAST4,LINC02393,STON1,TPO,TTC41P,LOX" MicroRNA hsa-miR-593:PITA hsa-miR-593:PITA_TOP PITA 3.12E-05 1.66E-01 6.62E-05 6.06E-04 11 208 "MAP1B,MCC,BCL2L2,FCHO2,CDK18,HECTD1,ERBIN,TGFBI,SLAIN1,DCP2,LETM1" MicroRNA hsa-miR-6818-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.19E-05 1.70E-01 6.75E-05 6.18E-04 10 172 "ULK1,XPR1,LRRTM2,PIGG,ZNF329,ELOVL7,PLEKHA6,UFM1,MRPS14,UTP20" MicroRNA hsa-miR-219-5p:PITA hsa-miR-219-5p:PITA_TOP PITA 3.19E-05 1.70E-01 6.75E-05 6.18E-04 10 172 "PITPNM2,NCOA1,PDE4D,PDGFRA,AKAP6,ELOVL7,NR5A2,PCDH17,PPARGC1A,DCP2" MicroRNA hsa-miR-455-3p.2:TargetScan hsa-miR-455-3p.2 TargetScan 3.31E-05 1.76E-01 7.01E-05 6.42E-04 12 248 "ABL2,ARL1,CAMK4,CFL2,POU2F1,LACC1,G3BP2,ELK3,CCDC88A,MYT1L,NFASC,MSH6" MicroRNA hsa-miR-4517:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.32E-05 1.76E-01 7.02E-05 6.43E-04 8 107 "DDX55,CCNB1,COPA,LYSMD3,MTX3,CLIP1,LRCH1,LOX" MicroRNA hsa-miR-99b:mirSVR_lowEffct hsa-miR-99b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.35E-05 1.78E-01 7.08E-05 6.49E-04 10 173 "CDK7,ZNF595,LYSMD3,OGFOD2,DLEU1,NDUFAF7,LRRN2,FBXO11,NLRP2,MYO16" MicroRNA "TGCACTG,MIR-152:MSigDB" "TGCACTG,MIR-152:MSigDB" MSigDB 3.37E-05 1.79E-01 7.11E-05 6.51E-04 13 289 "NCOA1,STARD13,CFL2,SLC25A3,CLOCK,ITSN2,DMXL1,ARGLU1,FBXO11,PPARGC1A,XPO4,TENT2,NSD2" MicroRNA "TGCACTG,MIR-148B:MSigDB" "TGCACTG,MIR-148B:MSigDB" MSigDB 3.37E-05 1.79E-01 7.11E-05 6.51E-04 13 289 "NCOA1,STARD13,CFL2,SLC25A3,CLOCK,ITSN2,DMXL1,ARGLU1,FBXO11,PPARGC1A,XPO4,TENT2,NSD2" MicroRNA "TGCACTG,MIR-148A:MSigDB" "TGCACTG,MIR-148A:MSigDB" MSigDB 3.37E-05 1.79E-01 7.11E-05 6.51E-04 13 289 "NCOA1,STARD13,CFL2,SLC25A3,CLOCK,ITSN2,DMXL1,ARGLU1,FBXO11,PPARGC1A,XPO4,TENT2,NSD2" MicroRNA hsa-miR-5003-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-05 1.81E-01 7.18E-05 6.57E-04 9 139 "COG6,CCNB1IP1,STRN3,LACC1,CSNK1G3,VCAN,G2E3,GABRB1,IKBIP" MicroRNA hsa-miR-659:PITA hsa-miR-659:PITA_TOP PITA 3.44E-05 1.83E-01 7.27E-05 6.65E-04 12 249 "HOMEZ,ARHGAP5,NCOA1,PCSK1,ATAD2B,NCOR2,FNIP1,SDC1,SLC12A2,PDS5B,PPARGC1A,DOCK9" MicroRNA hsa-miR-193b:mirSVR_highEffct hsa-miR-193b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.45E-05 1.83E-01 7.27E-05 6.66E-04 16 421 "NFATC4,NOVA1,SMIM14,TAPT1,SREK1,NUDT12,DNMT3A,EGLN3,RAPGEF6,DRC1,ERBIN,PPARGC1A,ADAMTS19,ZMYM2,RMST,IFT88" MicroRNA hsa-miR-10a*:mirSVR_highEffct hsa-miR-10a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.45E-05 1.84E-01 7.28E-05 6.66E-04 14 332 "PNP,CCDC122,NTN4,CLIP1,N4BP2L2,SLC30A6,IVNS1ABP,PKD2L2,MEGF10,RAPGEF6,ATP11A,RAB2B,DCP2,AMTN" MicroRNA hsa-miR-221-3p:TargetScan hsa-miR-221-3p TargetScan 3.47E-05 1.85E-01 7.31E-05 6.69E-04 15 376 "RALGAPA1,MDM4,PITPNM2,ARHGEF7,NOVA1,ATAD2B,NOP9,RNF4,PCGF3,PLEKHA6,CCDC88A,MYT1L,GPR12,IGF1,KIT" MicroRNA hsa-miR-222-3p:TargetScan hsa-miR-222-3p TargetScan 3.47E-05 1.85E-01 7.31E-05 6.69E-04 15 376 "RALGAPA1,MDM4,PITPNM2,ARHGEF7,NOVA1,ATAD2B,NOP9,RNF4,PCGF3,PLEKHA6,CCDC88A,MYT1L,GPR12,IGF1,KIT" MicroRNA hsa-miR-30e-3p:Functional MTI Functional MTI miRTarbase 3.52E-05 1.87E-01 7.41E-05 6.79E-04 10 174 "MDM4,NFKBIA,CACNA1E,CAMK4,SYT2,EPGN,TNFSF13B,GABRA2,C12orf73,LMNB1" MicroRNA hsa-let-7c-5p:Functional MTI Functional MTI miRTarbase 3.52E-05 1.87E-01 7.42E-05 6.79E-04 18 516 "MDM4,SLC5A6,CHD1,BRI3BP,CEP135,SNX17,DHX9,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,SLC12A2,POTEM,ZBTB37,STRN,METAP2,LTA4H" MicroRNA hsa-miR-183-5p.2:TargetScan hsa-miR-183-5p.2 TargetScan 3.54E-05 1.88E-01 7.45E-05 6.82E-04 19 565 "CUL4A,ATP2B4,NOVA1,CACNA1E,LDB2,HOMER1,PREPL,F11R,SACS,RABGAP1L,NTN4,FOXO1,NPAS3,NFASC,PCDH17,PSME4,GPR12,LCP1,IFT88" MicroRNA hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA_TOP PITA 3.55E-05 1.89E-01 7.46E-05 6.83E-04 16 422 "ASTN1,FCHO2,LDB2,PDE4D,NRXN1,PIK3C2B,BOD1L1,LRRTM2,G3BP2,ETF1,PCGF3,FGF9,SLC8A1,KIF21B,PPARGC1A,ZNF470" MicroRNA hsa-miR-4743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.55E-05 1.89E-01 7.46E-05 6.83E-04 8 108 "MRPL57,SMIM14,EIF2AK2,FOXG1,PLEKHA6,METAP2,KLF12,LOX" MicroRNA hsa-miR-1206:PITA hsa-miR-1206:PITA_TOP PITA 3.69E-05 1.96E-01 7.76E-05 7.10E-04 10 175 "ARHGAP5,STXBP6,NOVA1,CEP135,RB1,TBC1D19,FNIP1,NR5A2,PPARGC1A,ADAMTS19" MicroRNA hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 3.69E-05 1.96E-01 7.76E-05 7.10E-04 10 175 "MAP1B,APBB2,PCSK1,DHFR,DNMT3A,PCGF3,KDM5B,NPAS3,KLF12,IL6ST" MicroRNA hsa-miR-7162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.69E-05 1.96E-01 7.76E-05 7.10E-04 10 175 "MDM4,MMP17,APAF1,CAD,PDE6B,BRI3BP,ZNF329,TOMM40L,PLEKHA6,ZDHHC20" MicroRNA hsa-miR-647:PITA hsa-miR-647:PITA_TOP PITA 3.69E-05 1.96E-01 7.76E-05 7.10E-04 10 175 "ASCL1,NCOA1,CADM3,NOVA1,FCHO2,DCLK1,CHD1,DNAJC27,ATP8A2,LHX9" MicroRNA hsa-miR-519d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.80E-05 2.02E-01 7.98E-05 7.31E-04 9 141 "NCOA1,POU2F1,HEATR5A,FAM129A,MPHOSPH9,PCBD2,KDM3B,ADAM17,GUF1" MicroRNA hsa-miR-510:PITA hsa-miR-510:PITA_TOP PITA 3.80E-05 2.02E-01 7.98E-05 7.31E-04 9 141 "ABL2,SLC4A4,NOVA1,LDB2,MATR3,FNIP1,SLC30A6,SLC8A1,ACIN1" MicroRNA hsa-miR-412:PITA hsa-miR-412:PITA_TOP PITA 3.80E-05 2.02E-01 7.98E-05 7.31E-04 9 141 "SEMA6A,NCOA1,MBNL2,TMEM129,GOLGA2P5,KIF21B,ERBIN,PSME4,GRSF1" MicroRNA hsa-miR-619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.86E-05 2.05E-01 8.09E-05 7.40E-04 16 425 "BCL2L2,PIK3C2B,THAP6,C12orf65,CEP135,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,SBNO1,PCGF3,N4BP2L2,ZNF446,GTF2H3,TXK,SELENOI" MicroRNA hsa-miR-6814-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-05 2.06E-01 8.12E-05 7.44E-04 10 176 "XPR1,THAP6,CEP135,UBXN2A,BRMS1L,KIF21B,GOLGA3,SPIC,ACSL6,LMLN" MicroRNA hsa-miR-509-3-5p:PITA hsa-miR-509-3-5p:PITA_TOP PITA 4.02E-05 2.14E-01 8.41E-05 7.70E-04 13 294 "ARHGAP5,FCHO2,UHMK1,DCLK1,CDK17,ATAD2B,AKAP6,G3BP2,RAN,G2E3,ACIN1,PDS5B,TDG" MicroRNA hsa-miR-509-5p:PITA hsa-miR-509-5p:PITA_TOP PITA 4.02E-05 2.14E-01 8.41E-05 7.70E-04 13 294 "ARHGAP5,FCHO2,UHMK1,DCLK1,CDK17,ATAD2B,AKAP6,G3BP2,RAN,G2E3,ACIN1,PDS5B,TDG" MicroRNA hsa-miR-379-3p:TargetScan hsa-miR-379-3p TargetScan 4.05E-05 2.15E-01 8.47E-05 7.75E-04 11 214 "APBB2,CACNA1E,CDKL2,CAMK4,ITGBL1,HEATR5A,MATR3,JPH4,LHX9,FAM49A,LMLN" MicroRNA hsa-miR-411-3p:TargetScan hsa-miR-411-3p TargetScan 4.05E-05 2.15E-01 8.47E-05 7.75E-04 11 214 "APBB2,CACNA1E,CDKL2,CAMK4,ITGBL1,HEATR5A,MATR3,JPH4,LHX9,FAM49A,LMLN" MicroRNA hsa-miR-382-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-05 2.16E-01 8.50E-05 7.78E-04 7 81 "UHMK1,ITGBL1,SLC30A6,CD244,TXK,SELENOI,SPATA13" MicroRNA hsa-miR-127-3p:mirSVR_highEffct hsa-miR-127-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.07E-05 2.16E-01 8.50E-05 7.78E-04 7 81 "BLZF1,ATP1A2,SPATA18,EIF2D,KMT5A,TPTE2,TTC41P" MicroRNA hsa-miR-335-5p:TargetScan hsa-miR-335-5p TargetScan 4.22E-05 2.24E-01 8.82E-05 8.08E-04 11 215 "BCL2L2,NRXN1,CLOCK,PRKD1,CEP350,RASA1,ARGLU1,CHFR,GABRB1,KLF12,IRF1" MicroRNA hsa-miR-339-5p:TargetScan hsa-miR-339-5p TargetScan 4.25E-05 2.26E-01 8.87E-05 8.12E-04 9 143 "ABL2,NOVA1,PDE4D,CHD1,NRXN1,FLT1,BRMS1L,NFASC,PCDH17" MicroRNA hsa-miR-3121-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-05 2.26E-01 8.87E-05 8.12E-04 9 143 "WDR35,COCH,WDR1,ZNF329,MARVELD2,PLEKHA6,GABRB1,ATP11A,CCDC169" MicroRNA hsa-miR-544a:TargetScan hsa-miR-544a TargetScan 4.27E-05 2.27E-01 8.90E-05 8.15E-04 10 178 "MPZL1,POU2F1,DMXL1,G3BP2,SBNO1,FLT1,CCDC88A,RAPGEF6,HSPH1,KIF2A" MicroRNA hsa-miR-6083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.27E-05 2.27E-01 8.90E-05 8.15E-04 10 178 "RGS5,ATP2B4,BRI3BP,REST,SRP72,PPARGC1A,STRN,ZMYM2,LMLN,LMNB1" MicroRNA hsa-miR-4473:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.29E-05 2.28E-01 8.96E-05 8.20E-04 6 56 "ADD1,RNF4,CLIP1,FLT1,IL6ST,LMLN" MicroRNA hsa-miR-513b-5p:Functional MTI Functional MTI miRTarbase 4.49E-05 2.39E-01 9.35E-05 8.56E-04 9 144 "TOGARAM2,NOS1AP,SREK1,OCIAD1,SETDB2,PACRGL,SH3BP2,ZBTB37,ZNF324B" MicroRNA hsa-let-7g-5p:Functional MTI Functional MTI miRTarbase 4.61E-05 2.45E-01 9.60E-05 8.79E-04 14 341 "MDM4,SLC5A6,BRI3BP,CEP135,DCAF8,SNX17,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,POTEM,ZBTB37,STRN" MicroRNA hsa-miR-1281:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.69E-05 2.49E-01 9.77E-05 8.94E-04 10 180 "ATP1A2,TAF1B,THAP6,STRN3,ZNF419,ATP6AP1L,FCAR,BRMS1L,UTP20,ACSL6" MicroRNA hsa-miR-627:PITA hsa-miR-627:PITA_TOP PITA 4.73E-05 2.52E-01 9.86E-05 9.02E-04 9 145 "ABL2,KCTD12,NOVA1,NRXN1,CEP350,DNMT3A,NR5A2,KMT5A,KIF3C" MicroRNA hsa-miR-6773-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-05 2.52E-01 9.86E-05 9.02E-04 9 145 "ABL2,NLN,STRN3,PIGG,LATS2,BRMS1L,KLF12,GUF1,LMLN" MicroRNA hsa-miR-4258:mirSVR_lowEffct hsa-miR-4258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.75E-05 2.53E-01 9.89E-05 9.06E-04 14 342 "MCFD2,RGSL1,SNX17,LRPPRC,SLC22A17,SLC34A2,CGREF1,C1orf112,GABRB1,NAAA,KDM3B,METAP2,RAB2B,MFSD2B" MicroRNA hsa-miR-5195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-05 2.53E-01 9.90E-05 9.06E-04 7 83 "UBXN2A,DMXL1,UTP15,IVNS1ABP,ADAM17,TGFBI,TNR" MicroRNA hsa-miR-4255:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-05 2.53E-01 9.90E-05 9.06E-04 7 83 "RGS5,MCFD2,WDFY2,SUCO,IVNS1ABP,PSME4,NSD2" MicroRNA hsa-miR-636:PITA hsa-miR-636:PITA_TOP PITA 4.91E-05 2.61E-01 1.02E-04 9.35E-04 10 181 "SEMA6A,ATP2B4,NOVA1,FCHO2,PCDH9,DCLK1,MBNL2,ETF1,PKD2L2,DOCK9" MicroRNA "CAGTATT,MIR-200B:MSigDB" "CAGTATT,MIR-200B:MSigDB" MSigDB 4.94E-05 2.63E-01 1.03E-04 9.39E-04 16 434 "NOVA1,CDK17,CFL2,CSNK1G3,MATR3,KLHL3,DNMT3A,FOXG1,SUPT20H,BRMS1L,NR5A2,PDS5B,NEDD1,KLF12,SPTSSA,LCP1" MicroRNA "CAGTATT,MIR-200C:MSigDB" "CAGTATT,MIR-200C:MSigDB" MSigDB 4.94E-05 2.63E-01 1.03E-04 9.39E-04 16 434 "NOVA1,CDK17,CFL2,CSNK1G3,MATR3,KLHL3,DNMT3A,FOXG1,SUPT20H,BRMS1L,NR5A2,PDS5B,NEDD1,KLF12,SPTSSA,LCP1" MicroRNA "CAGTATT,MIR-429:MSigDB" "CAGTATT,MIR-429:MSigDB" MSigDB 4.94E-05 2.63E-01 1.03E-04 9.39E-04 16 434 "NOVA1,CDK17,CFL2,CSNK1G3,MATR3,KLHL3,DNMT3A,FOXG1,SUPT20H,BRMS1L,NR5A2,PDS5B,NEDD1,KLF12,SPTSSA,LCP1" MicroRNA hsa-miR-4261:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-05 2.73E-01 1.07E-04 9.77E-04 7 84 "G3BP2,LIMCH1,KMT5A,TMPO,TMEM174,PABPN1,SPATA13" MicroRNA hsa-miR-6895-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.14E-05 2.74E-01 1.07E-04 9.77E-04 10 182 "ULK1,LRRTM2,ZNF329,KLHL12,ELOVL7,FGF9,PLEKHA6,UFM1,MRPS14,LHX9" MicroRNA hsa-miR-199a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.22E-05 2.78E-01 1.08E-04 9.92E-04 8 114 "CDK7,CDK17,PTGS2,TMEM161B,FLT1,SLC30A6,MCCC2,IGF1" MicroRNA hsa-miR-590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-05 2.79E-01 1.09E-04 9.95E-04 15 390 "APC,CCNB1,PAH,SMIM14,POU2F1,UBXN2A,DMXL1,SLC35F6,TMEM33,FOXG1,SLC8A1,SPIC,TENT2,SELENOI,IL6ST" MicroRNA hsa-miR-4278:mirSVR_lowEffct hsa-miR-4278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.46E-05 2.90E-01 1.13E-04 1.04E-03 23 792 "ZNF542P,MORN2,SNCAIP,NOS1AP,ZNF586,SPATA18,COG3,CEP350,KLHL3,SGCG,G2E3,STPG4,YPEL5,EFR3B,KDM5B,PPARGC1A,NSD2,ZNF10,FAM49A,KCNN2,KIR2DS4,LINC00442,AXDND1" MicroRNA hsa-miR-379-5p:Functional MTI Functional MTI miRTarbase 5.55E-05 2.95E-01 1.15E-04 1.05E-03 7 85 "MCC,MDM4,SLC5A6,BRI3BP,TBC1D19,PCGF3,PABPN1" MicroRNA hsa-miR-4802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-05 2.95E-01 1.15E-04 1.05E-03 7 85 "PGGT1B,TOGARAM2,MATR3,REST,NDUFAF7,POTEM,LPIN1" MicroRNA hsa-miR-493-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.56E-05 2.96E-01 1.15E-04 1.05E-03 8 115 "DDX55,ARHGAP5,PCSK1,EIF2B1,PCGF3,FNIP1,TDG,ZNF550" MicroRNA hsa-miR-99a*:mirSVR_highEffct hsa-miR-99a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.56E-05 2.96E-01 1.15E-04 1.05E-03 8 115 "MYBPC1,CD84,ARHGEF7,ZNF664,ATAD2B,FAM129A,TMPO,PLB1" MicroRNA hsa-miR-892b:PITA hsa-miR-892b:PITA_TOP PITA 5.64E-05 3.00E-01 1.17E-04 1.07E-03 11 222 "ASCL1,CACNA1E,MPZL1,ZNF664,CDK17,KLHL3,KDM3B,PCDH17,PPARGC1A,XPO4,HMGCR" MicroRNA hsa-miR-504-5p.1:TargetScan hsa-miR-504-5p.1 TargetScan 5.64E-05 3.00E-01 1.17E-04 1.07E-03 10 184 "FBRSL1,BLZF1,BCL2L2,NCOR2,DNMT3A,EFNA5,SDC1,FLT1,ATP8A2,CNTN2" MicroRNA hsa-miR-342-3p:Functional MTI Functional MTI miRTarbase 5.64E-05 3.00E-01 1.17E-04 1.07E-03 13 304 "BIRC6,ATP6V1G3,RILPL1,PKP1,STRN3,F11R,ATG10,RGS4,TMEM33,ZNF419,NFASC,STRN,ZDHHC20" MicroRNA hsa-miR-147a:Functional MTI Functional MTI miRTarbase 5.85E-05 3.11E-01 1.21E-04 1.11E-03 9 149 "SEMA6A,RGS5,FBRSL1,PNP,POU2F1,CLOCK,DCAF8,SLC35F6,LAD1" MicroRNA hsa-miR-1537:mirSVR_lowEffct hsa-miR-1537:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.87E-05 3.12E-01 1.21E-04 1.11E-03 18 537 "PITPNM2,AACS,ARHGEF7,LDB2,TBC1D4,MPHOSPH9,PCBD2,UTP15,FGF9,STAB2,RUBCNL,IVNS1ABP,SLC22A4,NMNAT2,ERAP1,NPAS3,COMMD6,GRSF1" MicroRNA hsa-miR-584:PITA hsa-miR-584:PITA_TOP PITA 5.90E-05 3.14E-01 1.22E-04 1.12E-03 10 185 "XPR1,PITX1,AKAP6,LRRTM2,BIVM,ETF1,TMED2,GTF3C2,KIF2A,RPGRIP1" MicroRNA hsa-miR-513c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-05 3.14E-01 1.22E-04 1.12E-03 10 185 "MCFD2,ASCL1,XPR1,NUP37,NGDN,EIF2AK2,SLC8A1,NEDD1,TFDP1,LMNB1" MicroRNA hsa-miR-3529-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.91E-05 3.14E-01 1.22E-04 1.12E-03 8 116 "MDM4,GNPTAB,POU2F1,FAM169A,MTX3,SLC22A17,NDUFAF7,SPATA13" MicroRNA hsa-miR-1273a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-05 3.18E-01 1.23E-04 1.13E-03 7 86 "PIGR,FAM129A,TMEM33,PCBD2,PAICS,GUF1,UBC" MicroRNA hsa-miR-653:PITA hsa-miR-653:PITA_TOP PITA 6.03E-05 3.21E-01 1.24E-04 1.14E-03 13 306 "MAP1B,BIRC6,NOVA1,TM9SF2,HOMER1,CLOCK,DMXL1,OCIAD1,MBNL2,SLC8A1,CCDC88A,PDS5B,BAZ1A" MicroRNA hsa-miR-6845-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.05E-05 3.22E-01 1.25E-04 1.14E-03 12 264 "NLN,COG6,BCL2L2,EPN1,POU2F1,CSNK1G3,UBXN2A,KLHL12,ATP6AP1L,FGF9,ZNF667,GALP" MicroRNA "CACTTTG,MIR-520G:MSigDB" "CACTTTG,MIR-520G:MSigDB" MSigDB 6.11E-05 3.25E-01 1.26E-04 1.15E-03 11 224 "APBB2,CFL2,PITX1,DCAF8,WDR1,ETF1,FOXO1,NBEA,NPAS3,KLF12,NSD2" MicroRNA "CACTTTG,MIR-520H:MSigDB" "CACTTTG,MIR-520H:MSigDB" MSigDB 6.11E-05 3.25E-01 1.26E-04 1.15E-03 11 224 "APBB2,CFL2,PITX1,DCAF8,WDR1,ETF1,FOXO1,NBEA,NPAS3,KLF12,NSD2" MicroRNA "GTGACTT,MIR-224:MSigDB" "GTGACTT,MIR-224:MSigDB" MSigDB 6.16E-05 3.28E-01 1.27E-04 1.16E-03 9 150 "MAP1B,SLC4A4,KCTD12,CAST,PDGFRA,MBNL2,GPN1,HMGCR,ZDHHC20" MicroRNA hsa-miR-3155a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-05 3.34E-01 1.29E-04 1.18E-03 8 117 "ATP1A2,THAP6,HEATR5A,PREPL,ARL6IP4,TOMM40L,NUBPL,UGGT2" MicroRNA hsa-miR-3944-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-05 3.34E-01 1.29E-04 1.18E-03 8 117 "MDM4,MYBPC1,G3BP2,MEMO1,CLIP1,NPAS3,PGAM5,LAD1" MicroRNA hsa-miR-3155b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-05 3.34E-01 1.29E-04 1.18E-03 8 117 "ATP1A2,THAP6,HEATR5A,PREPL,ARL6IP4,TOMM40L,NUBPL,UGGT2" MicroRNA hsa-miR-216b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.28E-05 3.34E-01 1.29E-04 1.18E-03 8 117 "NRL,UHMK1,BRI3BP,CEP135,MPHOSPH8,SACS,ATG10,CCDC169" MicroRNA hsa-miR-892a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.37E-05 3.39E-01 1.31E-04 1.20E-03 6 60 "NRL,FAM163A,RB1,MSH6,AP4S1,IL6ST" MicroRNA hsa-miR-1538:mirSVR_highEffct hsa-miR-1538:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.44E-05 3.43E-01 1.32E-04 1.21E-03 7 87 "PCK2,RNF31,TACC3,DHRS4,NCSTN,RIMBP2,GUF1" MicroRNA hsa-miR-627-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.44E-05 3.43E-01 1.32E-04 1.21E-03 13 308 "RALGAPA1,NLN,COG6,ASCL1,PPP1R3E,CD84,GPR180,UGT2B28,POU2F1,VCAN,FNIP1,SH3BP2,FAM151B" MicroRNA hsa-miR-513a-3p:Functional MTI Functional MTI miRTarbase 6.46E-05 3.43E-01 1.33E-04 1.21E-03 10 187 "MCFD2,ASCL1,XPR1,NUP37,NGDN,EIF2AK2,SLC8A1,NEDD1,TFDP1,LMNB1" MicroRNA hsa-miR-1205:PITA hsa-miR-1205:PITA_TOP PITA 6.62E-05 3.52E-01 1.36E-04 1.24E-03 11 226 "SLC4A4,PPP1R12B,RILPL1,SNTG2,G3BP2,ACIN1,MYT1L,NMNAT2,KDM3B,PSME4,ADAMTS19" MicroRNA "CCTGTGA,MIR-513:MSigDB" "CCTGTGA,MIR-513:MSigDB" MSigDB 6.67E-05 3.55E-01 1.37E-04 1.25E-03 8 118 "RGS5,DNM3,RAN,ZNF329,NPAS3,PPARGC1A,UBE2K,NSD2" MicroRNA hsa-miR-425*:mirSVR_highEffct hsa-miR-425*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.75E-05 3.59E-01 1.38E-04 1.27E-03 10 188 "WDR19,CD1E,PCSK1,UBXN2A,SNX17,SLC9C2,CWC27,NUBPL,SCYL2,NPAS3" MicroRNA hsa-miR-181a*:mirSVR_lowEffct hsa-miR-181a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.88E-05 3.66E-01 1.41E-04 1.29E-03 13 310 "COG6,SCFD2,VIT,PGGT1B,ARSK,GORAB,ACIN1,PPIP5K2,STON1,WDR36,AMTN,LIG4,PABPN1" MicroRNA hsa-miR-451:mirSVR_highEffct hsa-miR-451:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.88E-05 3.66E-01 1.41E-04 1.29E-03 11 227 "WDFY2,SREK1,PARPBP,EGLN3,POLR1D,MYO16,ADGRL3,ZBTB49,HEXB,ADAMTS19,TTC41P" MicroRNA hsa-miR-501-3p:TargetScan hsa-miR-501-3p TargetScan 7.18E-05 3.82E-01 1.47E-04 1.34E-03 9 153 "APC,CACNA1E,DCLK1,LYSMD3,BRI3BP,SBNO1,PCDH17,ATP11A,KLF12" MicroRNA hsa-miR-3973:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.18E-05 3.82E-01 1.47E-04 1.34E-03 9 153 "MCC,CDKL2,PIK3C2B,PKP1,G2E3,ZNF446,OXGR1,TMPO,NSD2" MicroRNA hsa-miR-502-3p:TargetScan hsa-miR-502-3p TargetScan 7.18E-05 3.82E-01 1.47E-04 1.34E-03 9 153 "APC,CACNA1E,DCLK1,LYSMD3,BRI3BP,SBNO1,PCDH17,ATP11A,KLF12" MicroRNA hsa-miR-1271:PITA hsa-miR-1271:PITA_TOP PITA 7.29E-05 3.88E-01 1.49E-04 1.36E-03 14 356 "SEMA6A,CUL4A,NOVA1,LDB2,NRXN1,HOMER1,TBC1D4,NTN4,FOXO1,SLC22A5,MYO16,PCDH17,SLC7A8,ZBTB41" MicroRNA hsa-miR-4500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.34E-05 3.90E-01 1.50E-04 1.37E-03 13 312 "MDM4,SLC5A6,BRI3BP,CEP135,SNX17,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,POTEM,ZBTB37,STRN" MicroRNA hsa-miR-4458:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.34E-05 3.90E-01 1.50E-04 1.37E-03 13 312 "MDM4,SLC5A6,BRI3BP,CEP135,SNX17,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,POTEM,ZBTB37,STRN" MicroRNA "GGGACCA,MIR-133A:MSigDB" "GGGACCA,MIR-133A:MSigDB" MSigDB 7.37E-05 3.92E-01 1.51E-04 1.38E-03 10 190 "BCL2L2,KIAA0040,SREK1,FOXG1,SFSWAP,THADA,RAPGEF6,NFASC,SLC7A8,IL6ST" MicroRNA "GGGACCA,MIR-133B:MSigDB" "GGGACCA,MIR-133B:MSigDB" MSigDB 7.37E-05 3.92E-01 1.51E-04 1.38E-03 10 190 "BCL2L2,KIAA0040,SREK1,FOXG1,SFSWAP,THADA,RAPGEF6,NFASC,SLC7A8,IL6ST" MicroRNA hsa-miR-18a-5p:TargetScan hsa-miR-18a-5p TargetScan 7.44E-05 3.96E-01 1.52E-04 1.39E-03 11 229 "NCOA1,PDE4D,HOMER1,POU2F1,HEATR5A,PLEKHA6,CCDC88A,KDM5B,KLHL20,IGF1,KIT" MicroRNA hsa-miR-18b-5p:TargetScan hsa-miR-18b-5p TargetScan 7.44E-05 3.96E-01 1.52E-04 1.39E-03 11 229 "NCOA1,PDE4D,HOMER1,POU2F1,HEATR5A,PLEKHA6,CCDC88A,KDM5B,KLHL20,IGF1,KIT" MicroRNA hsa-miR-876-5p:TargetScan hsa-miR-876-5p TargetScan 7.44E-05 3.96E-01 1.52E-04 1.39E-03 11 229 "NLN,ATP6V1G3,HOMEZ,PPP1R12B,CAMK4,GNPDA2,MTX3,DNAJC27,GABRB1,HAL,LHX9" MicroRNA hsa-miR-4711-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-05 3.96E-01 1.52E-04 1.39E-03 7 89 "FAM177A1,FAM163A,BRMS1L,AP4S1,ZNF550,IGF1,ZDHHC20" MicroRNA hsa-miR-1251:PITA hsa-miR-1251:PITA_TOP PITA 7.45E-05 3.96E-01 1.52E-04 1.39E-03 7 89 "APBB2,GNPTAB,CEP120,CLIP4,ZNF219,KLF12,IGF1" MicroRNA hsa-miR-580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.45E-05 3.96E-01 1.52E-04 1.39E-03 7 89 "ARHGEF7,CDK17,LYSMD3,TMEM33,TGFBI,TNR,SPTSSA" MicroRNA "AGGTGCA,MIR-500:MSigDB" "AGGTGCA,MIR-500:MSigDB" MSigDB 7.45E-05 3.96E-01 1.52E-04 1.39E-03 7 89 "NCOA1,CAMK4,MATR3,FOXG1,NBEA,IVNS1ABP,PDS5B" MicroRNA hsa-miR-222:PITA hsa-miR-222:PITA_TOP PITA 7.49E-05 3.98E-01 1.52E-04 1.40E-03 12 270 "RALGAPA1,PITPNM2,APAF1,NOVA1,UHMK1,PCSK1,ATAD2B,ZFYVE16,CCDC88A,PPARGC1A,SPTSSA,KIT" MicroRNA hsa-miR-1185-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.51E-05 4.00E-01 1.53E-04 1.40E-03 8 120 "PITPNM2,PCSK1,PFKFB2,PGGT1B,ZNF256,BRMS1L,EML4,MSH6" MicroRNA hsa-miR-96:PITA hsa-miR-96:PITA_TOP PITA 7.73E-05 4.11E-01 1.57E-04 1.44E-03 14 358 "SEMA6A,CUL4A,NOVA1,LDB2,NRXN1,HOMER1,TBC1D4,NTN4,FOXO1,SLC22A5,MYO16,PCDH17,SLC7A8,ZBTB41" MicroRNA hsa-miR-342-3p:TargetScan hsa-miR-342-3p TargetScan 7.74E-05 4.11E-01 1.57E-04 1.44E-03 11 230 "MDM4,PPFIA4,APBB2,PDGFRA,CFL2,DNM3,RASA1,RGS4,NBEA,PCDH17,IRF1" MicroRNA hsa-miR-596:mirSVR_highEffct hsa-miR-596:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.82E-05 4.16E-01 1.59E-04 1.46E-03 13 314 "PDGFRA,ADGRF3,FBXL5,IPO4,GMPR2,FLT1,SUPT20H,UGGT2,NAAA,MRPS27,KDM3B,LINC01551,HMGCR" MicroRNA hsa-miR-3151-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.92E-05 4.21E-01 1.61E-04 1.47E-03 5 39 "SLC5A8,CFL2,NOS1AP,POTEM,MRPS27" MicroRNA hsa-miR-92b*:mirSVR_lowEffct hsa-miR-92b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.93E-05 4.22E-01 1.61E-04 1.48E-03 16 452 "ADD1,ADORA1,PITPNM2,DHX37,AACS,NCOR2,SPATA18,PTPRC,DTD2,KIRREL1,MAEA,ETF1,DDX51,METAP2,CNTN2,LINC00272" MicroRNA hsa-miR-154-3p:TargetScan hsa-miR-154-3p TargetScan 7.96E-05 4.24E-01 1.62E-04 1.48E-03 8 121 "APC,PDE4D,DNMT3A,PCGF3,PPARGC1A,KLF12,ANKS1B,LHX9" MicroRNA hsa-miR-487a-3p:TargetScan hsa-miR-487a-3p TargetScan 7.96E-05 4.24E-01 1.62E-04 1.48E-03 8 121 "APC,PDE4D,DNMT3A,PCGF3,PPARGC1A,KLF12,ANKS1B,LHX9" MicroRNA hsa-miR-939:PITA hsa-miR-939:PITA_TOP PITA 8.00E-05 4.25E-01 1.62E-04 1.49E-03 7 90 "CADM3,BCL2L2,DCLK1,PEAR1,NFASC,TCF7,KLF12" MicroRNA hsa-miR-4709-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.00E-05 4.25E-01 1.62E-04 1.49E-03 7 90 "CCNB1,KIAA0040,ZNF219,PCBD2,TM9SF1,NT5C1B,NT5C1B-RDH14" MicroRNA hsa-miR-4446-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.04E-05 4.28E-01 1.63E-04 1.49E-03 11 231 "ABL2,RGS5,GPR180,UGT2B28,NGDN,TMEM161B,SLC30A6,GABRB1,NPAS3,UBE2K,LMLN" MicroRNA hsa-miR-7:PITA hsa-miR-7:PITA_TOP PITA 8.04E-05 4.28E-01 1.63E-04 1.49E-03 11 231 "SLC4A4,FCHO2,CHAMP1,PDE4D,STRN3,G3BP2,FCGR3B,GJB6,KDM3B,KMT5A,IGSF8" MicroRNA hsa-miR-3144-5p:mirSVR_highEffct hsa-miR-3144-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.07E-05 4.29E-01 1.64E-04 1.50E-03 13 315 "RNASE9,DCAF8,RGS12,ARHGEF40,GABRB1,MAEL,HPCAL1,STARD4,KIR2DL1,KIR2DL4,KIR2DS4,KIR3DL1,MFSD2B" MicroRNA hsa-miR-302f:PITA hsa-miR-302f:PITA_TOP PITA 8.32E-05 4.42E-01 1.68E-04 1.54E-03 12 273 "MAP1B,MYH7,PPP1R12B,CACNA1E,PDE4D,CFL2,CEP350,FAM114A1,ADGRL3,TDG,KLF12,POC5" MicroRNA hsa-miR-221:PITA hsa-miR-221:PITA_TOP PITA 8.32E-05 4.42E-01 1.68E-04 1.54E-03 12 273 "RALGAPA1,PITPNM2,APAF1,NOVA1,UHMK1,PCSK1,ATAD2B,ZFYVE16,CCDC88A,PPARGC1A,SPTSSA,KIT" MicroRNA hsa-miR-4524a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.33E-05 4.43E-01 1.69E-04 1.54E-03 13 316 "ATP1A2,SLC5A6,CD1D,BIVM,TMEM33,ZNF419,SBNO1,BRMS1L,PPARGC1A,GTF2H3,PGAM5,SDR39U1,LETM1" MicroRNA "ATACTGT,MIR-144:MSigDB" "ATACTGT,MIR-144:MSigDB" MSigDB 8.40E-05 4.47E-01 1.70E-04 1.56E-03 10 193 "SEMA6A,PDE4D,PFKFB2,ITSN2,SREK1,FOXG1,FOXO1,CCDC88A,SLC12A2,PABPN1" MicroRNA hsa-miR-4742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.44E-05 4.49E-01 1.70E-04 1.56E-03 8 122 "UHMK1,SMIM14,EPGN,NGDN,KLHL3,SLC30A6,KHNYN,LETM1" MicroRNA hsa-miR-3121-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.44E-05 4.49E-01 1.70E-04 1.56E-03 8 122 "ABL2,SCARB1,UHMK1,WDR66,TOGARAM2,UBXN2A,IVNS1ABP,UHRF1BP1L" MicroRNA hsa-miR-423-3p:mirSVR_highEffct hsa-miR-423-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.44E-05 4.49E-01 1.70E-04 1.56E-03 8 122 "ACOX3,PROZ,CMTM5,DNMT3A,ETF1,FGF9,POLK,AP4S1" MicroRNA hsa-miR-215-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.44E-05 4.49E-01 1.70E-04 1.56E-03 8 122 "NLN,STRN3,PIGG,LATS2,FOXO1,BRMS1L,KLF12,LMLN" MicroRNA hsa-miR-496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.44E-05 4.49E-01 1.70E-04 1.56E-03 8 122 "UHMK1,GPR180,NGDN,EFNA5,NDUFAF7,MRPS27,SELENOI,ZBTB41" MicroRNA "CTACCTC,LET-7B:MSigDB" "CTACCTC,LET-7B:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,MIR-98:MSigDB" "CTACCTC,MIR-98:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7C:MSigDB" "CTACCTC,LET-7C:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7G:MSigDB" "CTACCTC,LET-7G:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7F:MSigDB" "CTACCTC,LET-7F:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7A:MSigDB" "CTACCTC,LET-7A:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7I:MSigDB" "CTACCTC,LET-7I:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7D:MSigDB" "CTACCTC,LET-7D:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA "CTACCTC,LET-7E:MSigDB" "CTACCTC,LET-7E:MSigDB" MSigDB 8.69E-05 4.62E-01 1.75E-04 1.60E-03 14 362 "SLAMF6,NCOA1,SLC4A4,PPP1R12B,SLC5A6,NOVA1,AKAP6,GNPTAB,DCUN1D2,PCGF3,SFSWAP,KIF21B,NFASC,ACSL6" MicroRNA hsa-miR-532-3p:PITA hsa-miR-532-3p:PITA_TOP PITA 8.75E-05 4.66E-01 1.76E-04 1.61E-03 9 157 "NEDD8,PDE4D,HECTD1,G3BP2,DNMT3A,NMNAT2,PPARGC1A,ZNF544,PABPN1" MicroRNA hsa-miR-30a-3p:Functional MTI Functional MTI miRTarbase 8.77E-05 4.66E-01 1.76E-04 1.61E-03 10 194 "MDM4,CACNA1E,CAMK4,SYT2,EPGN,VEZT,TNFSF13B,GABRA2,C12orf73,LMNB1" MicroRNA hsa-miR-8055:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.88E-05 4.72E-01 1.78E-04 1.63E-03 13 318 "ABL2,PIWIL1,STRN3,BRI3BP,BIVM,DMXL1,SLC35F6,ZNF419,PCGF3,ZBTB37,LINC01551,C12orf73,LMNB1" MicroRNA "CTTTGTA,MIR-524:MSigDB" "CTTTGTA,MIR-524:MSigDB" MSigDB 8.90E-05 4.73E-01 1.79E-04 1.64E-03 15 409 "ADD1,EP400,NCOA1,PCDH9,DCLK1,HECTD1,CRHBP,MBNL2,PCGF3,NBEA,NR5A2,ERBIN,PCDH17,SPTSSA,CDK2AP1" MicroRNA hsa-miR-645:mirSVR_highEffct hsa-miR-645:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.90E-05 4.73E-01 1.79E-04 1.64E-03 15 409 "MCFD2,ARHGEF7,FCRLB,ZNF664,CCDC122,RNF219,GUSBP3,UGT2A3,KLHL12,TM9SF1,SLC8A1,CMPK2,ZNF544,UGT2A1,RNF17" MicroRNA hsa-miR-371a-5p:TargetScan hsa-miR-371a-5p TargetScan 8.91E-05 4.74E-01 1.79E-04 1.64E-03 12 275 "ATP1A2,FGFRL1,PAH,CFL2,GPR180,EPN1,DLEU1,ELOVL7,PCDH17,GTF2H3,DCP2,ANKS1B" MicroRNA hsa-miR-1296:mirSVR_highEffct hsa-miR-1296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.02E-05 4.80E-01 1.81E-04 1.66E-03 11 234 "BCL2L2,PCK2,PDGFRA,THTPA,EPGN,DCAF8,TOMM40L,UFM1,GABRA2,ZNF26,LTA4H" MicroRNA hsa-miR-29c*:mirSVR_lowEffct hsa-miR-29c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.02E-05 4.80E-01 1.81E-04 1.66E-03 11 234 "BIRC6,ADD1,FAM193A,PCDH9,CEP120,PCGF3,TNFRSF19,ALKAL2,CGREF1,OXGR1,ZBED3-AS1" MicroRNA hsa-miR-4281:mirSVR_lowEffct hsa-miR-4281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.14E-05 4.86E-01 1.83E-04 1.68E-03 15 410 "WDR19,BCL2L2,RGSL1,LTB4R,MPC2,SNX17,RNF31,DNAJC27,PCGF3,SPON2,ZNF667,MYO16,ADAMTS19,IRF1,KIF3C" MicroRNA hsa-miR-4277:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.18E-05 4.88E-01 1.84E-04 1.68E-03 6 64 "SYT2,UBXN2A,G3BP2,POTEM,METAP2,ACSL6" MicroRNA hsa-miR-501-5p:Functional MTI Functional MTI miRTarbase 9.19E-05 4.89E-01 1.84E-04 1.69E-03 9 158 "CD84,SCARB1,CHD1,EFNA5,TLR6,GORAB,IVNS1ABP,SLC8A1,MYT1L" MicroRNA hsa-miR-2276-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.19E-05 4.89E-01 1.84E-04 1.69E-03 9 158 "TAF1B,PDGFRA,STRN3,MATR3,DNMT3A,ZNF419,PCGF3,VEZT,ACSL6" MicroRNA hsa-miR-571:PITA hsa-miR-571:PITA_TOP PITA 9.20E-05 4.89E-01 1.84E-04 1.69E-03 7 92 "ARHGAP5,PPP1R12B,CHD1,FOXO1,KIF21B,COP1,GTF3C2" MicroRNA hsa-miR-339-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.36E-05 4.98E-01 1.87E-04 1.72E-03 11 235 "NOVA1,RILPL1,BIVM,G3BP2,RAN,ZNF329,ELOVL7,UFM1,MRPS14,NCSTN,NSD2" MicroRNA hsa-miR-498:Functional MTI Functional MTI miRTarbase 9.45E-05 5.03E-01 1.89E-04 1.73E-03 13 320 "MATN3,SMIM15,SLC4A4,PCSK1,NRXN1,THAP6,ZNF329,BRMS1L,ZNF667,SPIC,GPN1,TXK,FAM151B" MicroRNA hsa-miR-558:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.54E-05 5.07E-01 1.91E-04 1.75E-03 10 196 "HOMEZ,PPP1R12B,CCNB1,GNPTAB,UBXN2A,PTGS2,TMEM33,STX2,FNIP1,MRPS14" MicroRNA hsa-miR-650:PITA hsa-miR-650:PITA_TOP PITA 9.54E-05 5.07E-01 1.91E-04 1.75E-03 10 196 "NCOA1,CPNE6,PIK3C2B,NCOR2,CSNK1G3,CEP350,KLHL3,SLC30A6,KIF21B,JPH4" MicroRNA hsa-miR-6830-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.85E-05 5.24E-01 1.97E-04 1.80E-03 7 93 "PITX1,G2E3,LRCH1,PCDH17,TFDP1,TNR,LOX" MicroRNA hsa-miR-1248:PITA hsa-miR-1248:PITA_TOP PITA 1.01E-04 5.37E-01 2.01E-04 1.84E-03 11 237 "BCL2L2,NOVA1,UHMK1,CSNK1G3,DNMT3A,EFNA5,PLEKHA6,PCDH17,METAP2,LMNB1,PABPN1" MicroRNA hsa-miR-433-3p:TargetScan hsa-miR-433-3p TargetScan 1.01E-04 5.37E-01 2.01E-04 1.84E-03 11 237 "CUL4A,B4GALT3,CDK17,GNPTAB,CEP135,MTX3,CLIP1,BRMS1L,NUBPL,PPARGC1A,HSP90B1" MicroRNA hsa-miR-30d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-04 5.38E-01 2.02E-04 1.85E-03 9 160 "MDM4,CACNA1E,CAMK4,SYT2,EPGN,TNFSF13B,GABRA2,C12orf73,LMNB1" MicroRNA hsa-miR-628-3p:PITA hsa-miR-628-3p:PITA_TOP PITA 1.01E-04 5.38E-01 2.02E-04 1.85E-03 9 160 "PCDH9,ATAD2B,SMC6,SLC8A1,PCDH17,TCF7,EML4,RIMBP2,KLF12" MicroRNA hsa-miR-133a-3p.1:TargetScan hsa-miR-133a-3p.1 TargetScan 1.02E-04 5.41E-01 2.03E-04 1.86E-03 15 414 "ABL2,PITPNM2,BCL2L2,ODC1,CSNK1G3,KIAA0040,NOS1AP,MPHOSPH9,RAPGEF6,GOLGA3,GPR161,IL6ST,LHX9,FAM49A,KIF3C" MicroRNA hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA_TOP PITA 1.02E-04 5.43E-01 2.03E-04 1.86E-03 12 279 "PITPNM2,SNX24,ATP2B4,PPP1R12B,ATAD2B,G3BP2,DNMT3A,KIRREL1,PCGF3,KMT5C,TDG,IGF1" MicroRNA hsa-miR-3664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-04 5.52E-01 2.07E-04 1.89E-03 10 198 "PIWIL1,HEATR5A,PIGG,TMEM33,BRMS1L,ZNF446,GRSF1,GUF1,LMLN,LETM1" MicroRNA hsa-miR-876-5p:PITA hsa-miR-876-5p:PITA_TOP PITA 1.04E-04 5.52E-01 2.07E-04 1.89E-03 10 198 "ATP6V1G3,SEMA6A,PPP1R12B,SNCAIP,TBC1D4,F11R,MTX3,MAEA,IVNS1ABP,KLF12" MicroRNA hsa-miR-5189-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-04 5.60E-01 2.10E-04 1.92E-03 7 94 "NLN,TAF1B,XPR1,TOGARAM2,ELOVL7,FLT1,PPIP5K2" MicroRNA hsa-miR-493-3p:TargetScan hsa-miR-493-3p TargetScan 1.06E-04 5.63E-01 2.11E-04 1.93E-03 8 126 "KIAA1211,FCRLB,PDE4D,EFNA5,RNF4,NFASC,HTR2A,KCNJ9" MicroRNA hsa-miR-1184:PITA hsa-miR-1184:PITA_TOP PITA 1.09E-04 5.78E-01 2.16E-04 1.98E-03 11 239 "ARHGAP5,PDE4D,ATAD2B,RAN,TOMM40L,ACIN1,PDS5B,KHNYN,TDG,BAZ1A,NSD2" MicroRNA hsa-miR-3622a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-04 5.80E-01 2.17E-04 1.99E-03 6 66 "APAF1,CLOCK,VEZT,SLC8A1,GABRB1,NSD2" MicroRNA hsa-miR-208b-3p:TargetScan hsa-miR-208b-3p TargetScan 1.11E-04 5.91E-01 2.21E-04 2.02E-03 9 162 "APC,NOVA1,CFL2,MTX3,ARGLU1,FNIP1,FOXG1,EML4,ANKS1B" MicroRNA hsa-miR-6818-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-04 5.91E-01 2.21E-04 2.02E-03 9 162 "SEMA6A,FBRSL1,FGFRL1,PNP,NRXN1,CLOCK,SLC35F6,MRPS27,TNR" MicroRNA hsa-miR-5582-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-04 5.91E-01 2.21E-04 2.02E-03 9 162 "CLOCK,SDC1,VEZT,SH3BP2,SLC8A1,ZBTB37,NSD2,TADA2B,SELENOI" MicroRNA hsa-miR-208a-3p:TargetScan hsa-miR-208a-3p TargetScan 1.11E-04 5.91E-01 2.21E-04 2.02E-03 9 162 "APC,NOVA1,CFL2,MTX3,ARGLU1,FNIP1,FOXG1,EML4,ANKS1B" MicroRNA hsa-miR-1224-5p:mirSVR_highEffct hsa-miR-1224-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-04 5.92E-01 2.21E-04 2.02E-03 20 669 "RALGAPA1,ARHGEF7,SLC5A6,NOVA1,AMDHD1,ZNF664,CFL2,PFKFB2,HOMER1,CEP135,CEP120,C14orf119,B3GLCT,RNASE2,GORAB,FNIP1,BRD8,MAST4,PSME4,LMNB1" MicroRNA hsa-miR-3692-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-04 5.94E-01 2.22E-04 2.03E-03 8 127 "UHMK1,TOGARAM2,ITSN2,NOS1AP,DMXL1,ZNF419,EFNA5,PABPN1" MicroRNA hsa-miR-20b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-04 5.99E-01 2.23E-04 2.05E-03 7 95 "APAF1,HECTD1,MARVELD2,PSME4,STARD4,IL6ST,IRF1" MicroRNA hsa-miR-4726-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-04 5.99E-01 2.23E-04 2.05E-03 10 200 "CEP135,SPATA18,ZNF329,RGS12,FCAR,RUBCNL,BRMS1L,ACSL6,KHNYN,GPN1" MicroRNA hsa-miR-425:PITA hsa-miR-425:PITA_TOP PITA 1.13E-04 5.99E-01 2.23E-04 2.05E-03 10 200 "MAP1B,CFL2,DNAJC27,FGF9,G2E3,PDS5B,HSPH1,ATP11A,IGF1,PABPN1" MicroRNA hsa-miR-212-5p:TargetScan hsa-miR-212-5p TargetScan 1.14E-04 6.04E-01 2.25E-04 2.06E-03 13 326 "ABL2,CUL4A,PITPNM2,BCL2L2,CACNA1E,CFL2,GPR180,PIK3C2B,EFNA5,ETF1,SDC1,HSPH1,CNTN2" MicroRNA hsa-miR-188-5p:TargetScan hsa-miR-188-5p TargetScan 1.17E-04 6.20E-01 2.31E-04 2.11E-03 9 163 "CD84,ODC1,PIK3C2B,RASA1,FNIP1,NBEA,NPAS3,KLF12,IL6ST" MicroRNA hsa-miR-5696:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-04 6.20E-01 2.31E-04 2.11E-03 9 163 "KIAA1211,SMIM14,DMXL1,RAN,RNASEL,TRAPPC13,ZBTB37,DCP2,ZMYM2" MicroRNA hsa-miR-96-5p:Functional MTI Functional MTI miRTarbase 1.17E-04 6.24E-01 2.32E-04 2.13E-03 10 201 "B4GALT3,SCARB1,RASA1,FOXO1,GABRB1,ATP8A2,TMPO,SLAIN1,YTHDC2,LOX" MicroRNA hsa-miR-550b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-04 6.28E-01 2.34E-04 2.14E-03 8 128 "MDM4,NOP14,RILPL1,MARVELD2,MRPS14,NT5C1B,GUF1,NT5C1B-RDH14" MicroRNA hsa-miR-4328:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-04 6.28E-01 2.34E-04 2.14E-03 8 128 "COG6,GPR180,PKP1,DMXL1,SBNO1,NMNAT2,IL6ST,ZBTB41" MicroRNA hsa-miR-486-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-04 6.31E-01 2.35E-04 2.15E-03 6 67 "ARHGAP5,PCCA,EPGN,G3BP2,FOXO1,ZDHHC20" MicroRNA hsa-miR-181c*:mirSVR_highEffct hsa-miR-181c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-04 6.40E-01 2.38E-04 2.18E-03 7 96 "CFL2,UGGT2,PPARGC1A,METAP2,HEXB,ZMYM2,LIG4" MicroRNA hsa-miR-4735-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-04 6.40E-01 2.38E-04 2.18E-03 7 96 "CAD,PCDH9,PDE4D,DCAF8,KLHL3,SUPT7L,CRB1" MicroRNA "GTACTGT,MIR-101:MSigDB" "GTACTGT,MIR-101:MSigDB" MSigDB 1.21E-04 6.45E-01 2.39E-04 2.19E-03 11 242 "PPFIA4,NOVA1,PDE4D,PIK3C2B,PTGS2,G3BP2,DNMT3A,ERBIN,SELENOI,ZBTB41,LMNB1" MicroRNA hsa-miR-4731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-04 6.50E-01 2.41E-04 2.21E-03 14 374 "ADD1,PPFIA4,BCL2L2,C12orf65,UBXN2A,OCIAD1,RABGAP1L,SLC35F6,C14orf119,SBNO1,N4BP2L2,ZNF446,GTF2H3,TXK" MicroRNA hsa-miR-640:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-04 6.50E-01 2.41E-04 2.21E-03 10 202 "SLC5A8,SLC35F6,DCUN1D2,DLEU1,TLR6,NUBPL,POTEM,DCP2,ZNF84,IRF1" MicroRNA hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA_TOP PITA 1.26E-04 6.69E-01 2.48E-04 2.27E-03 11 243 "ATP1A2,FGFRL1,ZNF664,PGGT1B,ATAD2B,EPN1,G3BP2,SMC6,MBNL2,KDM3B,PCDH17" MicroRNA hsa-miR-2909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-04 6.78E-01 2.52E-04 2.30E-03 5 43 "UHMK1,SREK1,TOMM40L,RUBCNL,NFASC" MicroRNA hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA_TOP PITA 1.28E-04 6.80E-01 2.52E-04 2.31E-03 9 165 "ADD1,CAMK4,PCDH9,CDK17,ATAD2B,ERBIN,UBE2K,TENT2,SPTSSA" MicroRNA hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 1.29E-04 6.86E-01 2.54E-04 2.33E-03 6 68 "CDK17,KIAA0040,TMEM161B,CCDC88A,TXK,PABPN1" MicroRNA hsa-miR-3148:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-04 6.93E-01 2.57E-04 2.35E-03 11 244 "MAP1B,MDM4,SLC5A6,PDE4D,LACC1,RAN,KLHL12,SLC8A1,LIMCH1,GABRB1,NUAK2" MicroRNA hsa-miR-6884-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-04 6.98E-01 2.58E-04 2.37E-03 17 522 "MATN3,MDM4,HOMEZ,UBXN2A,EIF2AK2,ZNF329,DTD2,TBC1D19,ARSK,ZCCHC8,SLC30A6,GOLGA3,GRSF1,HSP90B1,IGF1,PGAM5,FAM151B" MicroRNA hsa-miR-3915:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-04 6.99E-01 2.59E-04 2.37E-03 8 130 "MCFD2,APBB2,ASTN1,NUP37,POU2F1,NMNAT2,HSP90B1,LMNB1" MicroRNA hsa-miR-6892-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-04 7.05E-01 2.61E-04 2.39E-03 10 204 "ABL2,RGS5,UHMK1,PIGR,PKP1,UBXN2A,SREK1,ATP6AP1L,MRPS27,ZNF550" MicroRNA hsa-miR-593-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-04 7.12E-01 2.63E-04 2.41E-03 9 166 "NLN,ULK1,STRN3,LRRTM2,ZNF329,ELOVL7,PLEKHA6,UFM1,MRPS14" MicroRNA hsa-miR-567:PITA hsa-miR-567:PITA_TOP PITA 1.34E-04 7.12E-01 2.63E-04 2.41E-03 9 166 "CAMK4,STRN3,DNMT3A,RASA1,CLIP1,FNIP1,CCDC88A,PDS5B,ATP11A" MicroRNA hsa-miR-1204:mirSVR_lowEffct hsa-miR-1204:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-04 7.16E-01 2.65E-04 2.42E-03 18 574 "IL17D,FAM193A,ASCL1,CCNB1IP1,ARHGEF7,ADGRD1,CDK18,PITX1,PIGG,TINF2,ARSK,PIBF1,GOLGA2P5,LILRB1,DOCK9,TTC41P,MFSD2B,SKA3" MicroRNA hsa-miR-4701-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-04 7.18E-01 2.65E-04 2.43E-03 11 245 "ABL2,NLN,ATP1A2,CD84,SYT2,AKAP6,DMXL1,RABGAP1L,PCBD2,ZCCHC8,KIF21B" MicroRNA hsa-miR-6837-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-04 7.28E-01 2.69E-04 2.46E-03 7 98 "KCTD12,CEP135,PRKD1,RNF219,CENPJ,GRSF1,ZNF550" MicroRNA hsa-miR-1304-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-04 7.30E-01 2.70E-04 2.47E-03 17 524 "ABL2,TMEM132B,TAF1B,CD1D,FAM177A1,PIWIL1,STRN3,HEATR5A,UBXN2A,PIGG,ZNF419,ARSK,VEZT,BRMS1L,ACSL6,GRSF1,LMLN" MicroRNA hsa-miR-543:PITA hsa-miR-543:PITA_TOP PITA 1.38E-04 7.32E-01 2.70E-04 2.47E-03 18 575 "MAP1B,BIRC6,DCLK1,PCSK1,AKAP6,CLOCK,MATR3,SACS,ETF1,BRMS1L,PDS5B,NPAS3,PPARGC1A,TBC1D1,ATP11A,TFDP1,TGFBI,SLAIN1" MicroRNA "AAGCAAT,MIR-137:MSigDB" "AAGCAAT,MIR-137:MSigDB" MSigDB 1.38E-04 7.33E-01 2.71E-04 2.48E-03 10 205 "CUL4A,MYBPC1,ARHGEF7,NOVA1,TBC1D19,LIMCH1,NFASC,PPARGC1A,XPO4,KLF12" MicroRNA hsa-miR-556-5p:PITA hsa-miR-556-5p:PITA_TOP PITA 1.39E-04 7.37E-01 2.72E-04 2.49E-03 8 131 "MCFD2,PIK3C2B,STRN3,DTD2,GJA3,KLF12,ZBTB41,PABPN1" MicroRNA hsa-miR-3606-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-04 7.44E-01 2.74E-04 2.51E-03 6 69 "UHMK1,CEP350,G2E3,MCCC2,SDR39U1,ZDHHC20" MicroRNA hsa-miR-642:PITA hsa-miR-642:PITA_TOP PITA 1.40E-04 7.45E-01 2.74E-04 2.51E-03 9 167 "PDGFRA,ACIN1,SRP72,ERBIN,PCDH17,PPARGC1A,PSME4,KHNYN,HSP90B1" MicroRNA hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA_TOP PITA 1.40E-04 7.45E-01 2.74E-04 2.51E-03 9 167 "SYT2,PDE4D,CFL2,CLOCK,RASA1,LATS2,NBEA,SLC30A6,PCDH17" MicroRNA hsa-miR-604:mirSVR_highEffct hsa-miR-604:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-04 7.76E-01 2.86E-04 2.62E-03 7 99 "CENPBD1P1,ARHGEF7,NOVA1,POU2F1,BRMS1L,LINC01551,AP4S1" MicroRNA hsa-miR-3607-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-04 7.76E-01 2.86E-04 2.62E-03 7 99 "SMIM15,CCNB1IP1,NRXN1,ETF1,N4BP2,HGFAC,ZDHHC20" MicroRNA hsa-miR-25*:mirSVR_highEffct hsa-miR-25*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-04 7.77E-01 2.86E-04 2.62E-03 8 132 "POU2F1,ZNF586,POLR1D,NAAA,KDM3B,LPIN1,TGFBI,ANKS1B" MicroRNA hsa-miR-1273c:mirSVR_highEffct hsa-miR-1273c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.46E-04 7.77E-01 2.86E-04 2.62E-03 8 132 "CDKL4,PDGFRA,STK32B,FGF9,SDC1,CRB1,HPCAL1,CHPT1" MicroRNA hsa-miR-5582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-04 7.99E-01 2.94E-04 2.69E-03 11 248 "NLN,CD1D,PDGFRA,NUP37,GNPTAB,CLOCK,SUCO,UFM1,GABRB1,PPIP5K2,LMLN" MicroRNA hsa-miR-548ah-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-04 8.04E-01 2.95E-04 2.70E-03 12 291 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-548am-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-04 8.04E-01 2.95E-04 2.70E-03 12 291 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-4280:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-04 8.06E-01 2.96E-04 2.71E-03 6 70 "HECTD1,CSNK1G3,UBXN2A,PCBD2,SLC30A6,LOX" MicroRNA hsa-miR-411:PITA hsa-miR-411:PITA_TOP PITA 1.55E-04 8.26E-01 3.03E-04 2.77E-03 7 100 "MAP1B,ATP2B4,NEDD8,ATAD2B,FBXL5,KLHL3,FOXO1" MicroRNA "CTGTTAC,MIR-194:MSigDB" "CTGTTAC,MIR-194:MSigDB" MSigDB 1.55E-04 8.26E-01 3.03E-04 2.77E-03 7 100 "PITPNM2,ARHGAP5,CHD1,PFKFB2,DNMT3A,MBNL2,KLF12" MicroRNA hsa-miR-635:PITA hsa-miR-635:PITA_TOP PITA 1.55E-04 8.26E-01 3.03E-04 2.77E-03 7 100 "BTF3,UHMK1,RCBTB2,GPR180,KLHL3,ZNF219,FOXG1" MicroRNA hsa-miR-4281:mirSVR_highEffct hsa-miR-4281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-04 8.26E-01 3.03E-04 2.77E-03 7 100 "STXBP6,CFAP45,TINF2,FAM172A,MAEA,STAB2,IGSF8" MicroRNA hsa-miR-548h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.29E-01 3.04E-04 2.78E-03 12 292 "MDM4,MYBPC1,MPZL1,SYT2,CD1D,PDE4D,NRXN1,STRN3,FAM169A,G2E3,UFM1,FAM49A" MicroRNA hsa-miR-548bb-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.29E-01 3.04E-04 2.78E-03 12 292 "MDM4,MYBPC1,MPZL1,SYT2,CD1D,PDE4D,NRXN1,STRN3,FAM169A,G2E3,UFM1,FAM49A" MicroRNA hsa-miR-548j-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.29E-01 3.04E-04 2.78E-03 12 292 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-548z:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-04 8.29E-01 3.04E-04 2.78E-03 12 292 "MDM4,MYBPC1,MPZL1,SYT2,CD1D,PDE4D,NRXN1,STRN3,FAM169A,G2E3,UFM1,FAM49A" MicroRNA hsa-miR-578:PITA hsa-miR-578:PITA_TOP PITA 1.57E-04 8.37E-01 3.07E-04 2.81E-03 13 337 "STXBP6,NCOA1,LDB2,ATAD2B,SREK1,DNMT3A,RASA1,ELF1,FOXO1,FLT1,PCDH17,PPARGC1A,DOCK9" MicroRNA hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 1.58E-04 8.38E-01 3.07E-04 2.81E-03 15 431 "APC,B4GALT3,STARD13,BCL2L2,NUP37,STRN3,NCOR2,MATR3,SMC6,REST,ETF1,CD244,TBC1D1,TDG,LTA4H" MicroRNA hsa-miR-3197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-04 8.45E-01 3.09E-04 2.83E-03 5 45 "PDE6B,NCOR2,TBC1D19,HPCAL1,IGF1" MicroRNA hsa-miR-149:PITA hsa-miR-149:PITA_TOP PITA 1.60E-04 8.51E-01 3.11E-04 2.85E-03 9 170 "SLC4A4,BCL2L2,MPZL1,CDK17,SNCAIP,KLHL3,TNFRSF19,KDM3B,XPO4" MicroRNA hsa-miR-548ac:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.56E-01 3.12E-04 2.86E-03 12 293 "MDM4,MYBPC1,MPZL1,SYT2,CD1D,PDE4D,NRXN1,STRN3,FAM169A,G2E3,UFM1,FAM49A" MicroRNA hsa-miR-548ae-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.56E-01 3.12E-04 2.86E-03 12 293 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-548x-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.56E-01 3.12E-04 2.86E-03 12 293 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-548aj-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.56E-01 3.12E-04 2.86E-03 12 293 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-548aq-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-04 8.56E-01 3.12E-04 2.86E-03 12 293 "MYBPC1,CDKL2,MPZL1,SYT2,CD1D,PDGFRA,GNPTAB,ELK3,G2E3,UFM1,ADAM17,PPIP5K2" MicroRNA hsa-miR-26a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-04 8.72E-01 3.18E-04 2.91E-03 6 71 "ABL2,NLN,APAF1,LRPPRC,GABRB1,PPIP5K2" MicroRNA "AAGGGAT,MIR-188:MSigDB" "AAGGGAT,MIR-188:MSigDB" MSigDB 1.64E-04 8.72E-01 3.18E-04 2.91E-03 6 71 "PCDH9,FBXO11,NBEA,SLC12A2,KLF12,NSD2" MicroRNA hsa-miR-520a-5p:PITA hsa-miR-520a-5p:PITA_TOP PITA 1.67E-04 8.87E-01 3.23E-04 2.96E-03 11 251 "ABL2,NOVA1,CHD1,SNX6,RCHY1,DCAF8,RGS4,SLC8A1,IQGAP2,LMNB1,PABPN1" MicroRNA hsa-miR-525-5p:PITA hsa-miR-525-5p:PITA_TOP PITA 1.67E-04 8.87E-01 3.23E-04 2.96E-03 11 251 "ABL2,NOVA1,CHD1,SNX6,RCHY1,DCAF8,RGS4,SLC8A1,IQGAP2,LMNB1,PABPN1" MicroRNA hsa-miR-146b-5p:PITA hsa-miR-146b-5p:PITA_TOP PITA 1.67E-04 8.90E-01 3.24E-04 2.97E-03 9 171 "ABL2,NOVA1,RCHY1,LRRTM2,BIVM,NPAS3,EML4,KLF12,ZBTB41" MicroRNA hsa-miR-146a:PITA hsa-miR-146a:PITA_TOP PITA 1.67E-04 8.90E-01 3.24E-04 2.97E-03 9 171 "ABL2,NOVA1,RCHY1,LRRTM2,BIVM,NPAS3,EML4,KLF12,ZBTB41" MicroRNA hsa-miR-5580-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-04 8.92E-01 3.25E-04 2.97E-03 10 210 "DDX55,CFL2,BRI3BP,COCH,PACRGL,EIF2B1,SLC12A2,SRP72,RASSF6,ZMYM2" MicroRNA hsa-miR-1322:PITA hsa-miR-1322:PITA_TOP PITA 1.71E-04 9.07E-01 3.30E-04 3.02E-03 8 135 "FAM193A,NEDD8,SAP18,USP44,TOMM40L,TCF7,TGFBI,KLF12" MicroRNA hsa-miR-188-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-04 9.07E-01 3.30E-04 3.02E-03 8 135 "ABL2,MCFD2,ZNF256,GABRB1,RAPGEF6,MRPS27,TXK,SELENOI" MicroRNA hsa-miR-548l:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-04 9.30E-01 3.38E-04 3.10E-03 9 172 "SMIM15,CDKL2,UHMK1,CEP120,REST,EFNA5,ZBTB37,XPO4,IL6ST" MicroRNA hsa-miR-195-5p:Functional MTI Functional MTI miRTarbase 1.75E-04 9.31E-01 3.38E-04 3.10E-03 19 639 "ABL2,TBC1D14,MCFD2,BCL2L2,CDK17,PDE4D,GPR180,TM9SF2,NCOR2,SREK1,TMEM161B,CLIP4,LRPPRC,SBNO1,IVNS1ABP,PPIP5K2,COP1,TADA2B,SELENOI" MicroRNA hsa-miR-548d-3p:Functional MTI Functional MTI miRTarbase 1.77E-04 9.40E-01 3.42E-04 3.13E-03 12 296 "MDM4,MYBPC1,MPZL1,SYT2,CD1D,PDE4D,NRXN1,STRN3,FAM169A,G2E3,UFM1,FAM49A" MicroRNA hsa-miR-744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-04 9.49E-01 3.45E-04 3.16E-03 15 436 "ARHGAP5,SLC25A3,EPN1,COPA,MATR3,NOP9,RAN,TRAPPC12,TRIM28,ZNF256,TACC3,TMEM175,GAK,ATP11A,IGSF8" MicroRNA hsa-miR-141-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.80E-04 9.55E-01 3.47E-04 3.17E-03 8 136 "WDR35,TOGARAM2,POU2F1,HEATR5A,RNF219,STRN,UGT2A1,TXK" MicroRNA hsa-miR-133b:TargetScan hsa-miR-133b TargetScan 1.85E-04 9.86E-01 3.58E-04 3.28E-03 16 487 "ABL2,PITPNM2,BCL2L2,CSNK1G3,DMXL1,MTX3,MAEA,ETF1,FOXG1,GABRB1,IQGAP2,PCDH17,IL6ST,LHX9,FAM49A,KIF3C" MicroRNA hsa-miR-133a-3p.2:TargetScan hsa-miR-133a-3p.2 TargetScan 1.85E-04 9.86E-01 3.58E-04 3.28E-03 16 487 "ABL2,PITPNM2,BCL2L2,CSNK1G3,DMXL1,MTX3,MAEA,ETF1,FOXG1,GABRB1,IQGAP2,PCDH17,IL6ST,LHX9,FAM49A,KIF3C" MicroRNA "TCCAGAT,MIR-516-5P:MSigDB" "TCCAGAT,MIR-516-5P:MSigDB" MSigDB 1.87E-04 9.93E-01 3.60E-04 3.30E-03 7 103 "NCOA1,PIK3C2B,EGLN3,ARGLU1,EFNA5,ARL6IP4,NSD2" MicroRNA "GGTGTGT,MIR-329:MSigDB" "GGTGTGT,MIR-329:MSigDB" MSigDB 1.87E-04 9.93E-01 3.60E-04 3.30E-03 7 103 "PDE4D,SLC25A3,CSNK1G3,DNM3,NFASC,KLF12,IL6ST" MicroRNA hsa-miR-139-3p:mirSVR_highEffct hsa-miR-139-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-04 9.93E-01 3.60E-04 3.30E-03 7 103 "CD1D,FAM129A,RASA1,EFNA5,C1orf112,ALLC,LINC00442" MicroRNA hsa-miR-7641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-04 1.00E+00 3.64E-04 3.33E-03 8 137 "AKAP6,EPGN,ZNF256,BRMS1L,UFM1,POTEM,STARD4,IGF1" MicroRNA hsa-miR-370:PITA hsa-miR-370:PITA_TOP PITA 1.91E-04 1.00E+00 3.67E-04 3.36E-03 9 174 "FAM193A,SLC4A4,AP1G2,DNMT3A,LATS2,ZNF219,FOXO1,NFASC,KLF12" MicroRNA hsa-miR-7157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-04 1.00E+00 3.77E-04 3.45E-03 5 47 "FAM163A,CLIP4,STRN,AP4S1,LMNB1" MicroRNA "TCTGATC,MIR-383:MSigDB" "TCTGATC,MIR-383:MSigDB" MSigDB 1.96E-04 1.00E+00 3.77E-04 3.45E-03 5 47 "DCLK1,STRN3,IVNS1ABP,PCDH17,IRF1" MicroRNA "GCACCTT,MIR-18B:MSigDB" "GCACCTT,MIR-18B:MSigDB" MSigDB 1.98E-04 1.00E+00 3.81E-04 3.49E-03 7 104 "NCOA1,SUCO,CCDC88A,KDM5B,KLHL20,IGF1,KIT" MicroRNA "GCACCTT,MIR-18A:MSigDB" "GCACCTT,MIR-18A:MSigDB" MSigDB 1.98E-04 1.00E+00 3.81E-04 3.49E-03 7 104 "NCOA1,SUCO,CCDC88A,KDM5B,KLHL20,IGF1,KIT" MicroRNA hsa-miR-29c*:mirSVR_highEffct hsa-miR-29c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-04 1.00E+00 3.81E-04 3.49E-03 7 104 "CDK18,ADGRF3,OCIAD1,RB1,ADGRV1,CCDC92,FIP1L1" MicroRNA hsa-miR-599:PITA hsa-miR-599:PITA_TOP PITA 1.98E-04 1.00E+00 3.81E-04 3.49E-03 8 138 "BIRC6,SLC4A4,PDE4D,HEATR5A,CEP135,FOXO1,KMT5A,IGF1" MicroRNA hsa-miR-6835-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-04 1.00E+00 3.81E-04 3.49E-03 8 138 "PDE4D,GPR180,LYSMD3,DCAF8,REST,FAM172A,USP44,TDG" MicroRNA hsa-miR-296-5p:TargetScan hsa-miR-296-5p TargetScan 1.98E-04 1.00E+00 3.81E-04 3.49E-03 8 138 "NYNRIN,CADM3,CAD,PIK3C2B,EPN1,F10,GABRB1,NUAK2" MicroRNA hsa-miR-1294:PITA hsa-miR-1294:PITA_TOP PITA 1.99E-04 1.00E+00 3.82E-04 3.50E-03 9 175 "PITPNM2,ZNF784,BCL2L2,PDE4D,CFL2,SNX6,HOMER1,SPATA18,KLF12" MicroRNA hsa-miR-2467-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-04 1.00E+00 3.87E-04 3.54E-03 15 441 "RILPL1,CCNB1,PIGR,SUPT7L,SLC35F6,FAM129A,TMEM33,TXNDC15,MRPS14,DCAF11,SNRNP35,COX18,ATP6V0A2,GUF1,PGAM5" MicroRNA hsa-miR-511-5p:Functional MTI Functional MTI miRTarbase 2.10E-04 1.00E+00 4.03E-04 3.69E-03 7 105 "PITX1,FCGR3B,G2E3,LRCH1,KLHL20,TFDP1,LOX" MicroRNA hsa-miR-139-5p:Functional MTI Functional MTI miRTarbase 2.10E-04 1.00E+00 4.03E-04 3.69E-03 7 105 "ABL2,UHMK1,PDE4D,EPGN,NR5A2,TENT2,SPATA13" MicroRNA hsa-miR-369-5p:mirSVR_lowEffct hsa-miR-369-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-04 1.00E+00 4.04E-04 3.70E-03 10 216 "PCK2,GLT1D1,ITGBL1,PIGR,PRKD1,SPATA18,GP6,GABRA2,AP4S1,RASSF6" MicroRNA hsa-miR-5008-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-04 1.00E+00 4.15E-04 3.80E-03 5 48 "FAM163A,CLIP4,STRN,AP4S1,LMNB1" MicroRNA hsa-miR-6737-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-04 1.00E+00 4.15E-04 3.80E-03 5 48 "FAM163A,CLIP4,STRN,AP4S1,LMNB1" MicroRNA hsa-miR-4716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-04 1.00E+00 4.15E-04 3.80E-03 9 177 "ATP1A2,AKAP6,HEATR5A,CEP135,DMXL1,NUBPL,POTEM,ZNF274,GTF2H3" MicroRNA hsa-miR-5571-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-04 1.00E+00 4.18E-04 3.83E-03 10 217 "SMIM15,THAP6,GNPTAB,CLOCK,CEP135,ZNF329,UGGT2,ZNF544,TXK,PABPN1" MicroRNA hsa-miR-598:mirSVR_highEffct hsa-miR-598:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.19E-04 1.00E+00 4.18E-04 3.83E-03 11 259 "ADD1,FBRSL1,MSH2,NTN4,SGCG,GABRB1,CRB1,FZD10,TPO,ZNF140,FAM71C" MicroRNA hsa-miR-4477a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-04 1.00E+00 4.19E-04 3.83E-03 8 140 "CCNB1,BRI3BP,CEP135,MEMO1,CLIP1,UGT2A1,DOCK9,XPO4" MicroRNA hsa-miR-1182:Functional MTI Functional MTI miRTarbase 2.22E-04 1.00E+00 4.24E-04 3.88E-03 6 75 "NLN,CD1D,KLHL3,RB1,LATS2,PGAM5" MicroRNA hsa-miR-1270:Functional MTI Functional MTI miRTarbase 2.23E-04 1.00E+00 4.26E-04 3.90E-03 7 106 "C1orf116,HEATR5A,UBXN2A,REST,LRPPRC,HAL,ZNF550" MicroRNA hsa-miR-574-5p:PITA hsa-miR-574-5p:PITA_TOP PITA 2.23E-04 1.00E+00 4.26E-04 3.90E-03 7 106 "MAP1B,G3BP2,PCGF3,FNIP1,ANO4,RIMBP2,NSD2" MicroRNA hsa-miR-3652:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-04 1.00E+00 4.31E-04 3.94E-03 14 397 "ABL2,MMP17,THAP6,COPA,HEATR5A,CEP135,PIGG,SBNO1,ARSK,ADAM17,TEP1,GRSF1,GPR161,PABPN1" MicroRNA hsa-miR-4430:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-04 1.00E+00 4.31E-04 3.94E-03 14 397 "ABL2,MMP17,THAP6,COPA,HEATR5A,CEP135,PIGG,SBNO1,ARSK,ADAM17,TEP1,GRSF1,GPR161,PABPN1" MicroRNA hsa-miR-18a-3p:Functional MTI Functional MTI miRTarbase 2.27E-04 1.00E+00 4.34E-04 3.97E-03 13 350 "ATP2B4,ARHGEF7,TOGARAM2,POU2F1,SNX17,PIGG,DNMT3A,EGLN3,FNIP1,TACC3,PLEKHA6,XPO4,CDK2AP1" MicroRNA hsa-miR-8064:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-04 1.00E+00 4.38E-04 4.01E-03 8 141 "MAP1B,CADM3,WDR66,BRI3BP,FGFR3,PPARGC1A,STRN,GOLGA3" MicroRNA hsa-miR-590-5p:PITA hsa-miR-590-5p:PITA_TOP PITA 2.34E-04 1.00E+00 4.45E-04 4.08E-03 11 261 "RALGAPA1,FCHO2,CFL2,ATAD2B,LRRTM2,FBXO11,G2E3,XPO4,TGFBI,ZNF10,ZBTB41" MicroRNA hsa-miR-654-3p:PITA hsa-miR-654-3p:PITA_TOP PITA 2.35E-04 1.00E+00 4.48E-04 4.11E-03 10 219 "TMEM132B,CADM3,FGFRL1,CDK17,CKMT2,CEP350,MTX3,ETF1,PPARGC1A,KLF12" MicroRNA hsa-miR-620:Functional MTI Functional MTI miRTarbase 2.36E-04 1.00E+00 4.50E-04 4.12E-03 7 107 "C1orf116,HEATR5A,UBXN2A,REST,LRPPRC,HAL,ZNF550" MicroRNA hsa-miR-518b:mirSVR_lowEffct hsa-miR-518b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.38E-04 1.00E+00 4.53E-04 4.15E-03 16 498 "SFTA3,LRRC43,NRL,PFKFB2,NRXN1,TAPT1,ZNF586,SNX17,MEMO1,MARVELD2,N4BP2L2,MAST4,RNF212,RIMBP2,ADAMTS19,RMST" MicroRNA hsa-miR-3977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-04 1.00E+00 4.54E-04 4.16E-03 6 76 "ZNF664,PCGF3,ELOVL7,PAICS,ERBIN,ZBTB49" MicroRNA hsa-miR-532-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.44E-04 1.00E+00 4.64E-04 4.25E-03 10 220 "CAMK4,XPR1,WDFY2,PIGR,THAP6,DLEU1,RAPGEF6,MRPS27,ACSL6,TEP1" MicroRNA "CCTGCTG,MIR-214:MSigDB" "CCTGCTG,MIR-214:MSigDB" MSigDB 2.44E-04 1.00E+00 4.64E-04 4.25E-03 10 220 "SNX24,ATP2B4,SLC25A3,SFSWAP,VEZT,UGGT2,PCDH17,DOCK9,SLC7A8,ZBTB41" MicroRNA hsa-miR-1257:PITA hsa-miR-1257:PITA_TOP PITA 2.56E-04 1.00E+00 4.86E-04 4.45E-03 9 181 "KCTD12,LATS2,SCYL2,CCDC88A,NR5A2,SRP72,TMED2,GRSF1,ATP6V0A2" MicroRNA hsa-miR-4505:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-04 1.00E+00 4.86E-04 4.45E-03 9 181 "MMP17,PDE6B,CEP135,MEMO1,TRIM28,ARSK,ZCCHC8,ADAM17,PABPN1" MicroRNA hsa-miR-2861:mirSVR_highEffct hsa-miR-2861:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.56E-04 1.00E+00 4.87E-04 4.46E-03 14 402 "MSH2,MYH6,NOVA1,PDGFRA,WDFY2,EPGN,LOC439933,PTPRC,DNMT3A,POLR1D,CWC27,PPARGC1A,MAEL,TMEM174" MicroRNA hsa-miR-3160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-04 1.00E+00 4.87E-04 4.46E-03 6 77 "ATP1A2,CENPJ,PPIP5K2,HMGCR,TMEM174,ZDHHC20" MicroRNA hsa-miR-4313:mirSVR_highEffct hsa-miR-4313:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.62E-04 1.00E+00 4.98E-04 4.56E-03 10 222 "TSSK4,AKAP6,TAPT1,SPATA9,NBEA,TMEM183A,TBC1D1,C5orf56,DCP2,ZMYM2" MicroRNA hsa-miR-302c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-04 1.00E+00 5.03E-04 4.61E-03 8 144 "SNX24,VCAN,MATR3,RAN,ETF1,GABRB1,EML4,ZNF550" MicroRNA hsa-miR-1237-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-04 1.00E+00 5.03E-04 4.61E-03 8 144 "RALGAPA1,ABL2,ADD1,RGS5,PPP1R3E,ATP6AP1L,POTEM,PABPN1" MicroRNA hsa-miR-1825:PITA hsa-miR-1825:PITA_TOP PITA 2.66E-04 1.00E+00 5.05E-04 4.62E-03 9 182 "ATP2B4,UHMK1,XPR1,CFL2,GPR180,PKD2L2,PCDH17,KLF12,KIT" MicroRNA hsa-miR-5787:Functional MTI Functional MTI miRTarbase 2.66E-04 1.00E+00 5.05E-04 4.62E-03 9 182 "MMP17,PDE6B,CEP135,MEMO1,TRIM28,ARSK,ZCCHC8,ADAM17,PABPN1" MicroRNA hsa-miR-377-3p:Non-Functional MTI Non-Functional MTI miRTarbase 2.75E-04 1.00E+00 5.21E-04 4.77E-03 11 266 "TMEM132B,ATP6V1G3,CADM3,UHMK1,PFKFB2,PKP1,F11R,NBEA,PLEKHA6,LILRB1,EML4" MicroRNA hsa-miR-7-5p:TargetScan hsa-miR-7-5p TargetScan 2.76E-04 1.00E+00 5.23E-04 4.79E-03 14 405 "MAP1B,CADM3,CHAMP1,PDE4D,G3BP2,DNMT3A,RB1,MEMO1,ELOVL7,POTEM,KDM3B,IGSF8,KLF12,PABPN1" MicroRNA hsa-miR-574-3p:mirSVR_highEffct hsa-miR-574-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.78E-04 1.00E+00 5.26E-04 4.82E-03 8 145 "STRN3,NGDN,SNX17,FBXL5,CEP350,GORAB,SLC15A4,FIP1L1" MicroRNA hsa-miR-490-5p:PITA hsa-miR-490-5p:PITA_TOP PITA 2.78E-04 1.00E+00 5.26E-04 4.82E-03 8 145 "ATP6V1G3,UHMK1,ETF1,CCDC88A,NR5A2,METAP2,TFDP1,LHX9" MicroRNA hsa-miR-1973:mirSVR_highEffct hsa-miR-1973:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-04 1.00E+00 5.30E-04 4.86E-03 7 110 "FGFRL1,PCDH9,VCAN,RB1,MBNL2,MAST4,CDK2AP1" MicroRNA hsa-miR-302d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-04 1.00E+00 5.30E-04 4.86E-03 7 110 "PIK3C2B,POU2F1,CLOCK,SLC15A4,XPO4,TFDP1,DCP2" MicroRNA hsa-miR-642a-5p:Functional MTI Functional MTI miRTarbase 2.82E-04 1.00E+00 5.33E-04 4.88E-03 10 224 "ABL2,RGS5,ATP2B4,PIGR,UBXN2A,SREK1,EGLN3,ATP6AP1L,MRPS27,ZNF550" MicroRNA "CACTGCC,MIR-449:MSigDB" "CACTGCC,MIR-449:MSigDB" MSigDB 2.83E-04 1.00E+00 5.36E-04 4.91E-03 11 267 "PDGFRA,C1orf116,AKAP6,STRN3,CSNK1G3,RNF4,SUCO,FOXG1,VEZT,CNTN2,KLF12" MicroRNA "CACTGCC,MIR-34C:MSigDB" "CACTGCC,MIR-34C:MSigDB" MSigDB 2.83E-04 1.00E+00 5.36E-04 4.91E-03 11 267 "PDGFRA,C1orf116,AKAP6,STRN3,CSNK1G3,RNF4,SUCO,FOXG1,VEZT,CNTN2,KLF12" MicroRNA "CACTGCC,MIR-34A:MSigDB" "CACTGCC,MIR-34A:MSigDB" MSigDB 2.83E-04 1.00E+00 5.36E-04 4.91E-03 11 267 "PDGFRA,C1orf116,AKAP6,STRN3,CSNK1G3,RNF4,SUCO,FOXG1,VEZT,CNTN2,KLF12" MicroRNA hsa-miR-3927-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-04 1.00E+00 5.45E-04 4.99E-03 9 184 "MDM4,SLC5A6,CEP135,MTX3,TBC1D19,PCGF3,ZBTB37,STRN,SPTSSA" MicroRNA hsa-miR-558:PITA hsa-miR-558:PITA_TOP PITA 2.91E-04 1.00E+00 5.50E-04 5.03E-03 8 146 "TBC1D14,BTF3,HECTD1,G3BP2,ETF1,PLEKHA6,SLC8A1,RIMBP2" MicroRNA hsa-miR-588:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.92E-04 1.00E+00 5.51E-04 5.04E-03 10 225 "ABL2,NLN,ATP1A2,CD84,SYT2,AKAP6,DMXL1,RABGAP1L,PCBD2,KIF21B" MicroRNA hsa-miR-4652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.96E-04 1.00E+00 5.58E-04 5.11E-03 7 111 "MRPL57,SMIM14,EIF2AK2,FOXG1,PLEKHA6,METAP2,KLF12" MicroRNA hsa-miR-409-3p:Functional MTI Functional MTI miRTarbase 2.96E-04 1.00E+00 5.58E-04 5.11E-03 7 111 "FCHO2,RNASEL,CCDC38,EFR3B,SRP54,MSH6,TMPO" MicroRNA hsa-miR-382-5p:Functional MTI Functional MTI miRTarbase 2.96E-04 1.00E+00 5.58E-04 5.11E-03 7 111 "XPR1,PFKFB2,KLHL3,G3BP2,ATG10,FNIP1,SPIC" MicroRNA hsa-miR-324-5p:TargetScan hsa-miR-324-5p TargetScan 2.96E-04 1.00E+00 5.58E-04 5.11E-03 7 111 "ABL2,CHD1,RAN,MEMO1,SBNO1,FBXO11,METAP2" MicroRNA hsa-miR-1307:mirSVR_lowEffct hsa-miR-1307:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.00E-04 1.00E+00 5.66E-04 5.18E-03 9 185 "CSNK1G3,TXNDC15,TOMM40L,P2RX2,ADGRL3,STON1,TMPO,PLB1,TTC41P" MicroRNA hsa-miR-6131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-04 1.00E+00 5.69E-04 5.21E-03 10 226 "ABL2,TMEM132B,HEATR5A,RABGAP1L,SBNO1,TLR6,PCBD2,ZCCHC8,NUBPL,ZNF446" MicroRNA "TGCTTTG,MIR-330:MSigDB" "TGCTTTG,MIR-330:MSigDB" MSigDB 3.03E-04 1.00E+00 5.70E-04 5.22E-03 12 314 "APBB2,APC,DCLK1,SLC25A3,CSNK1G3,MBNL2,ETF1,FOXG1,METAP2,TDG,DCP2,SELENOI" MicroRNA hsa-miR-4673:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-04 1.00E+00 5.74E-04 5.25E-03 8 147 "APAF1,CDK18,PRKD1,ZNF329,TOMM40L,PEAR1,SH3BP2,IGSF8" MicroRNA hsa-miR-200b-3p:Functional MTI Functional MTI miRTarbase 3.12E-04 1.00E+00 5.88E-04 5.38E-03 9 186 "MATR3,DNMT3A,FOXG1,FLT1,N4BP2,ERBIN,KLHL20,LMNB1,LOX" MicroRNA hsa-miR-6831-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-04 1.00E+00 5.88E-04 5.38E-03 9 186 "MDM4,SLC5A6,CEP135,MTX3,TBC1D19,PCGF3,ZBTB37,STRN,SPTSSA" MicroRNA hsa-miR-4422:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-04 1.00E+00 5.88E-04 5.39E-03 7 112 "PDE4D,GPR180,LYSMD3,DCAF8,REST,USP44,TDG" MicroRNA hsa-miR-4321:mirSVR_lowEffct hsa-miR-4321:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-04 1.00E+00 5.88E-04 5.39E-03 10 227 "APBB2,BLZF1,LINC02347,NOVA1,CACNA1E,CEP120,F11R,GABRA2,MIMT1,ADAM17" MicroRNA hsa-miR-6504-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.15E-04 1.00E+00 5.93E-04 5.43E-03 6 80 "PIWIL1,SLC35F6,ZNF419,ARSK,ADAM17,PABPN1" MicroRNA hsa-miR-662:mirSVR_highEffct hsa-miR-662:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-04 1.00E+00 5.99E-04 5.49E-03 8 148 "ADORA1,EPS8L1,PTGS2,POLR1D,ARSK,DDX51,ZNF605,MAEL" MicroRNA hsa-miR-3614-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-04 1.00E+00 6.08E-04 5.57E-03 10 228 "AACS,PGGT1B,MPHOSPH8,EIF2AK2,RB1,TBC1D19,ARSK,MCCC2,COX18,ATP6V0A2" MicroRNA hsa-miR-302b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.30E-04 1.00E+00 6.20E-04 5.68E-03 7 113 "PIK3C2B,POU2F1,CLOCK,SLC15A4,XPO4,TFDP1,DCP2" MicroRNA hsa-miR-548av-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 6.26E-04 5.73E-03 8 149 "SMIM15,CDKL2,UHMK1,CHD1,CEP120,EFNA5,ZBTB37,IL6ST" MicroRNA hsa-miR-8054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 6.26E-04 5.73E-03 8 149 "SMIM15,CDKL2,UHMK1,CHD1,CEP120,EFNA5,ZBTB37,IL6ST" MicroRNA hsa-miR-548k:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-04 1.00E+00 6.26E-04 5.73E-03 8 149 "SMIM15,CDKL2,UHMK1,CHD1,CEP120,EFNA5,ZBTB37,IL6ST" MicroRNA hsa-miR-6764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-04 1.00E+00 6.29E-04 5.76E-03 10 229 "FAM163A,SPATA18,ZNF329,RGS12,FCAR,RUBCNL,BRMS1L,ACSL6,GPN1,PABPN1" MicroRNA hsa-miR-433-3p:Functional MTI Functional MTI miRTarbase 3.37E-04 1.00E+00 6.32E-04 5.79E-03 6 81 "MDM4,FGF9,NUBPL,POTEM,ERBIN,HSP90B1" MicroRNA hsa-miR-4700-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-04 1.00E+00 6.32E-04 5.79E-03 6 81 "CHD1,TRIM28,ZNF446,GRSF1,UBE2K,SPATA13" MicroRNA hsa-miR-3064-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-04 1.00E+00 6.32E-04 5.79E-03 6 81 "PIWIL1,SLC35F6,ZNF419,ARSK,ADAM17,PABPN1" MicroRNA hsa-miR-3667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-04 1.00E+00 6.48E-04 5.94E-03 5 53 "NFATC4,RILPL1,UBXN2A,LMNB1,SKA3" MicroRNA hsa-miR-6515-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.51E-04 1.00E+00 6.57E-04 6.02E-03 9 189 "MYBPC1,PPP1R3E,SLC5A6,SMIM14,UBXN2A,TMEM175,LIMCH1,CENPJ,TMEM174" MicroRNA hsa-miR-208b:mirSVR_highEffct hsa-miR-208b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.51E-04 1.00E+00 6.57E-04 6.02E-03 9 189 "UVSSA,NFKBIA,ZNF595,FCRL5,ARGLU1,DLEU1,FOXG1,GABRA2,DOCK9" MicroRNA hsa-miR-3135:mirSVR_highEffct hsa-miR-3135:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-04 1.00E+00 6.60E-04 6.04E-03 11 274 "BIRC6,CDKL4,SLC4A4,CFAP54,MATR3,TRAPPC13,NBEA,ANKLE2,UTP20,ADGRA3,GTF3C2" MicroRNA "TGCTGCT,MIR-15B:MSigDB" "TGCTGCT,MIR-15B:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA "TGCTGCT,MIR-195:MSigDB" "TGCTGCT,MIR-195:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA "TGCTGCT,MIR-424:MSigDB" "TGCTGCT,MIR-424:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA "TGCTGCT,MIR-497:MSigDB" "TGCTGCT,MIR-497:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA "TGCTGCT,MIR-15A:MSigDB" "TGCTGCT,MIR-15A:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA "TGCTGCT,MIR-16:MSigDB" "TGCTGCT,MIR-16:MSigDB" MSigDB 3.56E-04 1.00E+00 6.65E-04 6.09E-03 17 569 "ARHGAP5,SLC4A4,BCL2L2,PCDH9,DCLK1,CDK17,CLOCK,TMEM33,LATS2,SUCO,SLC12A2,MYT1L,PCDH17,FZD10,GPN1,SELENOI,CHPT1" MicroRNA hsa-miR-4691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.59E-04 1.00E+00 6.70E-04 6.14E-03 10 231 "ADD1,PPP1R3E,CD84,NRL,CAMK4,ZNF664,ATP6AP1L,ZCCHC8,UFM1,C12orf73" MicroRNA "GTATTAT,MIR-369-3P:MSigDB" "GTATTAT,MIR-369-3P:MSigDB" MSigDB 3.65E-04 1.00E+00 6.80E-04 6.22E-03 9 190 "PDE4D,CFL2,KLHL3,MBNL2,FOXG1,FOXO1,SFSWAP,HSPH1,ADAMTS19" MicroRNA hsa-miR-18b:PITA hsa-miR-18b:PITA_TOP PITA 3.65E-04 1.00E+00 6.80E-04 6.22E-03 9 190 "NCOA1,PDE4D,CLOCK,SUCO,CCDC88A,KLHL20,TRPC4,IGF1,KIT" MicroRNA hsa-miR-18a:PITA hsa-miR-18a:PITA_TOP PITA 3.65E-04 1.00E+00 6.80E-04 6.22E-03 9 190 "NCOA1,PDE4D,CLOCK,SUCO,CCDC88A,KLHL20,TRPC4,IGF1,KIT" MicroRNA hsa-miR-6776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-04 1.00E+00 6.80E-04 6.22E-03 9 190 "ULK1,RILPL1,UBXN2A,FCRL2,MTX3,ARSK,COX18,FAM151B,LETM1" MicroRNA hsa-miR-1302:PITA hsa-miR-1302:PITA_TOP PITA 3.65E-04 1.00E+00 6.80E-04 6.22E-03 8 151 "NDRG2,SLC4A4,AKAP6,DCAF8,FBXO11,PDS5B,IQGAP2,ACSL6" MicroRNA hsa-miR-1180:mirSVR_highEffct hsa-miR-1180:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.65E-04 1.00E+00 6.80E-04 6.22E-03 8 151 "ARHGEF7,PCDH9,DNMT3A,SMC6,UTP15,TM9SF1,MCCC2,PABPN1" MicroRNA hsa-miR-221-3p:Functional MTI Functional MTI miRTarbase 3.67E-04 1.00E+00 6.83E-04 6.25E-03 13 368 "TMEM132B,ADD1,APAF1,HECTD1,RB1,RNF4,TRIM28,ACIN1,TMEM183A,ZBTB37,UBC,SPTSSA,KIT" MicroRNA hsa-miR-3161:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.67E-04 1.00E+00 6.83E-04 6.26E-03 7 115 "NUP37,POU2F1,UBXN2A,SREK1,SETDB2,SLC8A1,SRP54" MicroRNA hsa-miR-6792-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-04 1.00E+00 6.91E-04 6.32E-03 10 232 "ADD1,PPP1R3E,CD84,NRL,CAMK4,ZNF664,ATP6AP1L,ZCCHC8,UFM1,C12orf73" MicroRNA hsa-miR-1915-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-04 1.00E+00 6.91E-04 6.32E-03 10 232 "FAM163A,SPATA18,ZNF329,RGS12,FCAR,RUBCNL,BRMS1L,ACSL6,GPN1,PABPN1" MicroRNA hsa-miR-3157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.78E-04 1.00E+00 7.02E-04 6.43E-03 5 54 "COG6,UHMK1,POU2F1,BIVM,OCIAD1" MicroRNA hsa-miR-200a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.78E-04 1.00E+00 7.02E-04 6.43E-03 5 54 "MDM4,FCHO2,UHMK1,SLC5A8,CLIP1" MicroRNA hsa-miR-197:PITA hsa-miR-197:PITA_TOP PITA 3.81E-04 1.00E+00 7.08E-04 6.49E-03 8 152 "SEMA6A,PDGFRA,LYSMD3,MTX3,RAN,ETF1,CCDC88A,DOCK9" MicroRNA hsa-miR-4468:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.81E-04 1.00E+00 7.08E-04 6.49E-03 8 152 "PKP1,UBXN2A,G3BP2,LATS2,SPON2,PLEKHA6,ATP8A2,HSP90B1" MicroRNA hsa-miR-3187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.84E-04 1.00E+00 7.13E-04 6.53E-03 10 233 "ABL2,NLN,ATP1A2,CD84,SYT2,AKAP6,DMXL1,RABGAP1L,PCBD2,ACIN1" MicroRNA hsa-miR-4695-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.86E-04 1.00E+00 7.16E-04 6.56E-03 13 370 "TAF1B,EPGN,MPHOSPH8,EIF2AK2,SLC35F6,TMEM33,CCDC38,DCAF11,ZBTB37,SNRNP35,ATP6V0A2,HSP90B1,GUF1" MicroRNA hsa-miR-3934-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-04 1.00E+00 7.17E-04 6.57E-03 11 277 "TMEM132B,SMIM14,PIGG,DCUN1D2,DLEU1,N4BP2L2,ZCCHC8,BRMS1L,KHNYN,HPCAL1,IRF1" MicroRNA hsa-miR-2276-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-04 1.00E+00 7.30E-04 6.68E-03 9 192 "ABL2,RGS5,PIGR,UBXN2A,SREK1,ATP6AP1L,MRPS27,ZNF550,KCNJ9" MicroRNA hsa-miR-6778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-04 1.00E+00 7.30E-04 6.68E-03 9 192 "MCFD2,PDGFRA,DCAF8,CEP120,TRIM28,MRPS27,RAB2B,IGSF8,LAD1" MicroRNA hsa-miR-383-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.96E-04 1.00E+00 7.35E-04 6.73E-03 14 420 "MATN3,TAF1B,RILPL1,PDE6B,CCDC122,STRN3,ARSK,PCBD2,ZCCHC8,BRMS1L,GOLGA3,COX18,FAM151B,ZDHHC20" MicroRNA hsa-miR-629:PITA hsa-miR-629:PITA_TOP PITA 3.99E-04 1.00E+00 7.38E-04 6.75E-03 8 153 "SEMA6A,ARHGAP5,SLC25A3,CEP350,PLEKHA6,PCDH17,TENT2,IGF1" MicroRNA hsa-miR-2113:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-04 1.00E+00 7.38E-04 6.75E-03 8 153 "FBRSL1,WDR66,HOMER1,CLOCK,DMXL1,KLHL12,CLIP1,TFDP1" MicroRNA hsa-miR-6888-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-04 1.00E+00 7.38E-04 6.75E-03 8 153 "MRPL57,TMEM33,PLEKHA6,TEP1,KLF12,GUF1,ZDHHC20,LOX" MicroRNA hsa-miR-6864-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-04 1.00E+00 7.41E-04 6.79E-03 12 324 "ABL2,PIWIL1,STRN3,BIVM,ZNF419,TBC1D19,GABRB1,MCCC2,ERBIN,COX18,LINC01551,PABPN1" MicroRNA hsa-miR-3672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-04 1.00E+00 7.41E-04 6.79E-03 12 324 "ABL2,PIWIL1,STRN3,BIVM,ZNF419,TBC1D19,GABRB1,MCCC2,ERBIN,COX18,LINC01551,PABPN1" MicroRNA hsa-miR-1185-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.08E-04 1.00E+00 7.54E-04 6.90E-03 7 117 "PCSK1,PFKFB2,PGGT1B,ZNF256,BRMS1L,EML4,MSH6" MicroRNA hsa-miR-516b:PITA hsa-miR-516b:PITA_TOP PITA 4.09E-04 1.00E+00 7.56E-04 6.92E-03 9 193 "BCL2L2,PCDH9,DCLK1,PDGFRA,BIVM,EGLN3,EFNA5,ADGRL3,PABPN1" MicroRNA "ATGTCAC,MIR-489:MSigDB" "ATGTCAC,MIR-489:MSigDB" MSigDB 4.11E-04 1.00E+00 7.59E-04 6.95E-03 6 84 "NCOA1,NOVA1,NFXL1,PDE4D,CLOCK,THADA" MicroRNA hsa-miR-200b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.12E-04 1.00E+00 7.60E-04 6.96E-03 5 55 "MDM4,FCHO2,UHMK1,SLC5A8,CLIP1" MicroRNA hsa-miR-3129-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.12E-04 1.00E+00 7.60E-04 6.96E-03 5 55 "FCHO2,UGT2B28,GNPTAB,CLOCK,SPTSSA" MicroRNA hsa-miR-602:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.12E-04 1.00E+00 7.60E-04 6.96E-03 4 31 "TMEM132B,SPON2,MYO16,COX18" MicroRNA "GACTGTT,MIR-212:MSigDB" "GACTGTT,MIR-212:MSigDB" MSigDB 4.16E-04 1.00E+00 7.68E-04 7.03E-03 8 154 "SEMA6A,NOVA1,CFL2,RASA1,PCGF3,SLC30A6,NMNAT2,SPTSSA" MicroRNA "GACTGTT,MIR-132:MSigDB" "GACTGTT,MIR-132:MSigDB" MSigDB 4.16E-04 1.00E+00 7.68E-04 7.03E-03 8 154 "SEMA6A,NOVA1,CFL2,RASA1,PCGF3,SLC30A6,NMNAT2,SPTSSA" MicroRNA hsa-miR-4433a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-04 1.00E+00 7.68E-04 7.03E-03 13 373 "MMP17,APAF1,PIK3C2B,EPGN,EIF2AK2,ZNF329,TCTN2,TBC1D19,PLEKHA6,ZNF446,ZBTB49,HSP90B1,ZNF324B" MicroRNA hsa-miR-3180-3p:mirSVR_lowEffct hsa-miR-3180-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.18E-04 1.00E+00 7.71E-04 7.06E-03 18 631 "ACOX3,EP400,AMDHD1,WDFY2,PIK3C2B,THTPA,NCOR2,RNF31,POLR1D,PCGF3,SPON2,TACC3,ZNF274,KMT5A,SLC7A8,NPL,FCRL6,TMEM178A" MicroRNA "GTTTGTT,MIR-495:MSigDB" "GTTTGTT,MIR-495:MSigDB" MSigDB 4.25E-04 1.00E+00 7.83E-04 7.17E-03 10 236 "ARHGAP5,NCOA1,PDE4D,HOMER1,MBNL2,MYT1L,ATP8A2,STRN,EML4,IGF1" MicroRNA hsa-miR-545-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.29E-04 1.00E+00 7.91E-04 7.24E-03 7 118 "MPZL1,SYT2,TTC37,TMEM33,LATS2,MARVELD2,GABRA2" MicroRNA hsa-miR-7703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-04 1.00E+00 7.92E-04 7.25E-03 15 474 "CAD,RILPL1,CCNB1,PIGR,CLOCK,UBXN2A,F11R,MTX3,TMEM33,RNF4,PCBD2,PAICS,UBC,ZNF84,LETM1" MicroRNA hsa-miR-758:PITA hsa-miR-758:PITA_TOP PITA 4.35E-04 1.00E+00 8.00E-04 7.32E-03 8 155 "ATAD2B,STRN3,ELF1,NBEA,CHFR,PSME4,XPO4,GRSF1" MicroRNA hsa-miR-503:mirSVR_highEffct hsa-miR-503:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.35E-04 1.00E+00 8.00E-04 7.32E-03 8 155 "ITGBL1,THAP6,POLE,THTPA,DCAF8,MAST4,NCSTN,TTC7A" MicroRNA hsa-miR-1183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-04 1.00E+00 8.04E-04 7.37E-03 6 85 "HECTD1,CEP135,N4BP2,ERBIN,PSME4,ATP6V0A2" MicroRNA hsa-miR-492:PITA hsa-miR-492:PITA_TOP PITA 4.38E-04 1.00E+00 8.04E-04 7.37E-03 6 85 "RALGAPA1,NCOA1,ATAD2B,G3BP2,EFNA5,LATS2" MicroRNA hsa-miR-450b-3p:PITA hsa-miR-450b-3p:PITA_TOP PITA 4.38E-04 1.00E+00 8.04E-04 7.37E-03 6 85 "NEDD8,NOVA1,GPR180,CCDC92,TMED2,HSP90B1" MicroRNA hsa-miR-5583-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-04 1.00E+00 8.23E-04 7.54E-03 5 56 "FCHO2,UGT2B28,GNPTAB,CLOCK,SPTSSA" MicroRNA hsa-miR-660-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.49E-04 1.00E+00 8.25E-04 7.55E-03 13 376 "ABL2,ADD1,SLC4A4,PPP1R3E,RILPL1,PIWIL1,RABGAP1L,DNMT3A,ATP6AP1L,ZCCHC8,PCDH17,C12orf73,FAM151B" MicroRNA hsa-miR-211-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-04 1.00E+00 8.29E-04 7.59E-03 7 119 "RGS5,KLHL12,ZNF219,ZBTB37,ATP11A,GUF1,IGF1" MicroRNA hsa-miR-1252-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.54E-04 1.00E+00 8.33E-04 7.62E-03 8 156 "MDM4,MYBPC1,SLC5A6,TOGARAM2,EIF2AK2,LILRB1,TDG,TFDP1" MicroRNA hsa-miR-145-5p:Functional MTI Functional MTI miRTarbase 4.54E-04 1.00E+00 8.33E-04 7.62E-03 10 238 "NDRG2,SNX24,UBXN2A,DMXL1,F11R,UTP15,IVNS1ABP,ADAM17,TGFBI,TNR" MicroRNA hsa-miR-508-5p:PITA hsa-miR-508-5p:PITA_TOP PITA 4.57E-04 1.00E+00 8.39E-04 7.68E-03 9 196 "PCSK1,CEP350,FOXO1,KDM3B,PSME4,ATP11A,PPIP5K2,IGF1,KIT" MicroRNA hsa-miR-4311:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.57E-04 1.00E+00 8.39E-04 7.68E-03 9 196 "NEDD8,AKAP6,POU2F1,BRMS1L,PAICS,CCDC88A,PPARGC1A,TFDP1,HGFAC" MicroRNA hsa-miR-154:PITA hsa-miR-154:PITA_TOP PITA 4.57E-04 1.00E+00 8.39E-04 7.68E-03 9 196 "ATP7B,IL20,DMXL1,FNIP1,TADA1,STON1,XPO4,BAZ1A,ADAMTS19" MicroRNA hsa-miR-508-5p:Functional MTI Functional MTI miRTarbase 4.59E-04 1.00E+00 8.41E-04 7.70E-03 15 477 "CAD,RILPL1,CCNB1,PIGR,UBXN2A,DMXL1,KLHL3,MTX3,FAM129A,PCBD2,PAICS,COX18,TNR,UBC,LETM1" MicroRNA hsa-miR-21-5p:TargetScan hsa-miR-21-5p TargetScan 4.63E-04 1.00E+00 8.47E-04 7.76E-03 11 283 "MSH2,FCHO2,HECTD1,RASA1,FOXG1,FBXO11,NBEA,C1orf112,NPAS3,KLF12,IL6ST" MicroRNA hsa-miR-769-3p:PITA hsa-miR-769-3p:PITA_TOP PITA 4.66E-04 1.00E+00 8.53E-04 7.81E-03 6 86 "NEDD8,NOVA1,GPR180,CCDC92,TMED2,HSP90B1" MicroRNA hsa-miR-7159-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.66E-04 1.00E+00 8.53E-04 7.81E-03 6 86 "EPGN,TRAPPC13,GABRB1,ERBIN,PPIP5K2,LMNB1" MicroRNA hsa-miR-621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-04 1.00E+00 8.54E-04 7.82E-03 4 32 "TOGARAM2,MARVELD2,STRN,FAM49A" MicroRNA hsa-miR-548s:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-04 1.00E+00 8.54E-04 7.82E-03 14 427 "ABL2,NLN,ATP1A2,CD84,SYT2,AKAP6,DMXL1,RABGAP1L,ZNF329,TCTN2,ELOVL7,PCBD2,GRSF1,ATP6V0A2" MicroRNA hsa-miR-423-5p:TargetScan hsa-miR-423-5p TargetScan 4.73E-04 1.00E+00 8.65E-04 7.92E-03 8 157 "PITPNM2,CADM3,NFATC4,ODC1,KLHL3,FAM172A,NMNAT2,CNTN2" MicroRNA hsa-miR-431-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-04 1.00E+00 8.65E-04 7.92E-03 8 157 "CDKL2,THAP6,BIVM,BRMS1L,IKBIP,KLHL20,ACSL6,ZMYM2" MicroRNA hsa-miR-629-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.75E-04 1.00E+00 8.66E-04 7.93E-03 9 197 "CAMK4,POU2F1,KDM5B,RAPGEF6,UHRF1BP1L,MRPS27,ACSL6,TGFBI,PABPN1" MicroRNA hsa-miR-1233-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.75E-04 1.00E+00 8.66E-04 7.93E-03 9 197 "MCFD2,PDGFRA,DCAF8,CEP120,TRIM28,MRPS27,RAB2B,IGSF8,LAD1" MicroRNA "ACTGTAG,MIR-139:MSigDB" "ACTGTAG,MIR-139:MSigDB" MSigDB 4.75E-04 1.00E+00 8.66E-04 7.93E-03 7 120 "SLC25A3,IVNS1ABP,CHFR,PPARGC1A,PSME4,XPO4,HMGCR" MicroRNA hsa-miR-1296-5p:Functional MTI Functional MTI miRTarbase 4.75E-04 1.00E+00 8.66E-04 7.93E-03 7 120 "BCL2L2,PNP,TOMM40L,RUBCNL,C1orf112,NFASC,TMPO" MicroRNA hsa-miR-3622b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.75E-04 1.00E+00 8.66E-04 7.93E-03 7 120 "MMP17,PDE6B,NOS1AP,ZCCHC8,MRPS14,GPN1,FAM151B" MicroRNA hsa-miR-610:PITA hsa-miR-610:PITA_TOP PITA 4.75E-04 1.00E+00 8.66E-04 7.93E-03 7 120 "FAM193A,BCL2L2,ELK3,SLC8A1,GJA3,SLAIN1,PABPN1" MicroRNA hsa-miR-663b:mirSVR_highEffct hsa-miR-663b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.76E-04 1.00E+00 8.68E-04 7.95E-03 11 284 "PDGFRA,CHD1,DDX59,MPHOSPH9,DHRS2,TMEM156,ATP8A2,LPIN1,BRD8,RNF212,FIP1L1" MicroRNA hsa-miR-590-5p:TargetScan hsa-miR-590-5p TargetScan 4.76E-04 1.00E+00 8.68E-04 7.95E-03 11 284 "MSH2,FCHO2,HECTD1,RASA1,FOXG1,FBXO11,NBEA,C1orf112,NPAS3,KLF12,IL6ST" MicroRNA hsa-miR-320a:Functional MTI Functional MTI miRTarbase 4.77E-04 1.00E+00 8.70E-04 7.96E-03 17 584 "ADD1,TBC1D14,ULK1,EP400,PITX1,NOC4L,NOS1AP,RAN,FMO1,PAICS,IVNS1ABP,DCAF11,IKBIP,TMPO,GPN1,DCP2,LMNB1" MicroRNA "ACATATC,MIR-190:MSigDB" "ACATATC,MIR-190:MSigDB" MSigDB 4.87E-04 1.00E+00 8.86E-04 8.11E-03 5 57 "TBC1D14,PCDH9,CLOCK,NFASC,ANO4" MicroRNA hsa-miR-718:mirSVR_highEffct hsa-miR-718:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.87E-04 1.00E+00 8.86E-04 8.11E-03 5 57 "GLT1D1,SPATA18,DNMT3A,ARL6IP4,LMNB1" MicroRNA hsa-miR-6733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.92E-04 1.00E+00 8.96E-04 8.20E-03 9 198 "PDGFRA,EPN1,GNPTAB,LACC1,LATS2,KLHL12,ARSK,ARL6IP4,RAB2B" MicroRNA hsa-miR-3153:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.92E-04 1.00E+00 8.96E-04 8.20E-03 9 198 "PDGFRA,EPN1,GNPTAB,LACC1,LATS2,KLHL12,ARSK,ARL6IP4,RAB2B" MicroRNA hsa-miR-572:mirSVR_highEffct hsa-miR-572:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.96E-04 1.00E+00 9.02E-04 8.26E-03 6 87 "ARHGEF7,BRI3BP,COG3,BRD8,DOCK9,ANKS1B" MicroRNA hsa-miR-146b-5p:Functional MTI Functional MTI miRTarbase 4.99E-04 1.00E+00 9.08E-04 8.31E-03 7 121 "NOVA1,PDGFRA,COPA,UTP15,XPO4,RAB2B,KIT" MicroRNA hsa-miR-4251:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.99E-04 1.00E+00 9.08E-04 8.31E-03 7 121 "NUP37,KIAA0040,REST,CLIP4,POLR1D,HTR2A,FAM151B" MicroRNA hsa-miR-3924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.00E-04 1.00E+00 9.09E-04 8.32E-03 10 241 "MDM4,TMEM132B,DCAF8,MBNL2,CCDC38,SLC8A1,SRP72,UBE2K,IL6ST,ZBTB41" MicroRNA hsa-miR-6794-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-04 1.00E+00 9.35E-04 8.56E-03 8 159 "PIWIL1,HEATR5A,RAN,ATG10,EFNA5,BRMS1L,GRSF1,LMLN" MicroRNA hsa-miR-455-3p.1:TargetScan hsa-miR-455-3p.1 TargetScan 5.20E-04 1.00E+00 9.44E-04 8.64E-03 11 287 "NLN,BCL2L2,CAD,CDK17,NRXN1,DNMT3A,ATP8A2,GRSF1,MSH6,FZD10,C12orf73" MicroRNA hsa-miR-491-3p:PITA hsa-miR-491-3p:PITA_TOP PITA 5.20E-04 1.00E+00 9.44E-04 8.64E-03 11 287 "SEMA6A,NCOA1,NOVA1,FCHO2,PDE4D,IL20,B3GLCT,TBC1D19,CLIP1,FGF9,MYT1L" MicroRNA hsa-miR-944:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.24E-04 1.00E+00 9.52E-04 8.71E-03 7 122 "UHMK1,LYSMD3,RAN,UTP15,LIMCH1,DCP2,LMLN" MicroRNA hsa-miR-1272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.27E-04 1.00E+00 9.56E-04 8.75E-03 6 88 "MDM4,MYBPC1,TOGARAM2,G2E3,GRSF1,LETM1" MicroRNA "GAGACTG,MIR-452:MSigDB" "GAGACTG,MIR-452:MSigDB" MSigDB 5.27E-04 1.00E+00 9.56E-04 8.75E-03 6 88 "BCL2L2,DCLK1,UTP15,FBXO11,PCDH17,UBE2K" MicroRNA hsa-miR-1276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-04 1.00E+00 9.73E-04 8.90E-03 8 160 "DDX55,NEDD8,PGGT1B,AKAP6,POU2F1,USP44,UTP20,SKA3" MicroRNA hsa-miR-486-5p:TargetScan hsa-miR-486-5p TargetScan 5.51E-04 1.00E+00 9.97E-04 9.13E-03 7 123 "ARHGAP5,POU2F1,FGF9,FOXO1,KDM5B,GOLGA3,IGF1" MicroRNA hsa-miR-3622a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-04 1.00E+00 9.97E-04 9.13E-03 7 123 "MMP17,PDE6B,NOS1AP,ZCCHC8,MRPS14,GPN1,FAM151B" MicroRNA hsa-miR-1286:PITA hsa-miR-1286:PITA_TOP PITA 5.51E-04 1.00E+00 9.97E-04 9.13E-03 7 123 "CFL2,FBXO11,ACIN1,NFASC,PCDH17,CNTN2,KLF12" MicroRNA hsa-let-7a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-04 1.00E+00 9.97E-04 9.13E-03 7 123 "BTF3,PGGT1B,BRI3BP,OCIAD1,ZNF256,NDUFAF7,MSH6" MicroRNA hsa-let-7i*:mirSVR_lowEffct hsa-let-7i*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.66E-04 1.00E+00 1.03E-03 9.39E-03 11 290 "ARHGEF7,CDKL2,DCLK1,RGSL1,NR1H4,ALKAL2,NR5A2,PDS5B,RBKS,ZBTB37,CRB1" MicroRNA hsa-miR-488-5p:Functional MTI Functional MTI miRTarbase 5.71E-04 1.00E+00 1.03E-03 9.46E-03 5 59 "ATP2B4,POLE,DLEU1,POTEM,IL6ST" MicroRNA hsa-miR-339-3p:mirSVR_lowEffct hsa-miR-339-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.73E-04 1.00E+00 1.04E-03 9.49E-03 13 386 "AP1G2,CD1D,SNCAIP,RGS12,PACRGL,DDX51,C1orf112,GAK,DRC1,RIMBP2,PGAM5,CHPT1,FIP1L1" MicroRNA hsa-miR-32-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-04 1.00E+00 1.05E-03 9.57E-03 7 124 "SNX24,UHMK1,FAM169A,SBNO1,SPON2,PPARGC1A,ZDHHC20" MicroRNA hsa-miR-216a-5p:Functional MTI Functional MTI miRTarbase 5.82E-04 1.00E+00 1.05E-03 9.63E-03 8 162 "APAF1,CD84,UGT2B28,UBXN2A,ARSK,OXGR1,METAP2,ZNF324B" MicroRNA hsa-miR-4435:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.86E-04 1.00E+00 1.06E-03 9.70E-03 10 246 "ABL2,NLN,APAF1,ATP1A2,CD84,SYT2,AKAP6,DMXL1,RABGAP1L,PCBD2" MicroRNA hsa-miR-4477b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.94E-04 1.00E+00 1.07E-03 9.82E-03 6 90 "CAD,CD1D,COCH,PSME4,GOLGA3,CRB1" MicroRNA hsa-miR-3191:mirSVR_lowEffct hsa-miR-3191:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.96E-04 1.00E+00 1.08E-03 9.85E-03 16 542 "AACS,SPATA18,COG3,PARPBP,DTD2,ZNF219,ETF1,SLC22A17,FLT1,NPAS3,EMILIN1,TECRL,HPCAL1,LINC00272,KCNJ9,PABPN1" MicroRNA hsa-miR-4701-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.06E-04 1.00E+00 1.09E-03 1.00E-02 8 163 "ULK1,RILPL1,FCRL2,MTX3,COX18,FAM151B,KIT,LETM1" MicroRNA hsa-miR-6736-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.06E-04 1.00E+00 1.09E-03 1.00E-02 8 163 "ULK1,RILPL1,FCRL2,MTX3,COX18,FAM151B,KIT,LETM1" MicroRNA hsa-miR-6739-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.10E-04 1.00E+00 1.10E-03 1.01E-02 9 204 "PDGFRA,EPN1,GNPTAB,LACC1,LATS2,KLHL12,ARSK,ARL6IP4,RAB2B" MicroRNA hsa-miR-220c:PITA hsa-miR-220c:PITA_TOP PITA 6.10E-04 1.00E+00 1.10E-03 1.01E-02 9 204 "PCCA,CFL2,PITX1,NCOR2,SNX17,ZNF219,ETF1,NMU,GTF3C2" MicroRNA hsa-miR-2355-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-04 1.00E+00 1.11E-03 1.02E-02 5 60 "WDFY2,UBXN2A,PACRGL,GABRB1,IL6ST" MicroRNA hsa-miR-452-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-04 1.00E+00 1.14E-03 1.04E-02 6 91 "ATP2B4,LIMCH1,PCDH17,DCP2,ZNF470,ZDHHC20" MicroRNA hsa-miR-214*:mirSVR_highEffct hsa-miR-214*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.30E-04 1.00E+00 1.14E-03 1.04E-02 13 390 "CENPBD1P1,CDK18,VIT,CRYL1,F10,MRPS27,SRP72,METAP2,TFDP1,TNR,STARD4,CCDC169,AXDND1" MicroRNA "CATGTAA,MIR-496:MSigDB" "CATGTAA,MIR-496:MSigDB" MSigDB 6.31E-04 1.00E+00 1.14E-03 1.04E-02 8 164 "SEMA6A,ASCL1,LDB2,LRRTM2,TMEM33,NBEA,YPEL5,MYT1L" MicroRNA hsa-miR-376a:PITA hsa-miR-376a:PITA_TOP PITA 6.32E-04 1.00E+00 1.14E-03 1.04E-02 9 205 "MAP1B,PITPNM2,ARHGAP5,SLC4A4,GPR180,CSNK1G3,PRKD1,FBXO11,PCDH17" MicroRNA hsa-miR-376b:PITA hsa-miR-376b:PITA_TOP PITA 6.32E-04 1.00E+00 1.14E-03 1.04E-02 9 205 "MAP1B,PITPNM2,ARHGAP5,SLC4A4,GPR180,CSNK1G3,PRKD1,FBXO11,PCDH17" MicroRNA hsa-miR-192-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.36E-04 1.00E+00 1.14E-03 1.05E-02 7 126 "CCNB1,FCRLB,CSNK1G3,NR1H4,RNASEL,ATP6AP1L,FAM114A1" MicroRNA hsa-miR-3123:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.36E-04 1.00E+00 1.14E-03 1.05E-02 7 126 "WDR1,FAM228A,FOXO1,ZBTB37,TMED2,HSP90B1,LMNB1" MicroRNA hsa-miR-202-3p:Functional MTI Functional MTI miRTarbase 6.54E-04 1.00E+00 1.18E-03 1.08E-02 9 206 "MDM4,BRI3BP,LATS2,PCGF3,TOMM40L,POTEM,TNFSF13B,ZBTB37,KHNYN" MicroRNA hsa-miR-545-3p:Non-Functional MTI Non-Functional MTI miRTarbase 6.57E-04 1.00E+00 1.18E-03 1.08E-02 8 165 "MDM4,MCFD2,WDFY2,CSNK1G3,VCAN,UBXN2A,MPHOSPH8,PPIP5K2" MicroRNA hsa-miR-1262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.57E-04 1.00E+00 1.18E-03 1.08E-02 8 165 "ULK1,RILPL1,FCRL2,MTX3,COX18,FAM151B,KIT,LETM1" MicroRNA hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 6.57E-04 1.00E+00 1.18E-03 1.08E-02 8 165 "NUP37,CLOCK,CSNK1G3,SBNO1,FOXO1,GABRB1,PCDH17,MTUS2" MicroRNA hsa-miR-938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.66E-04 1.00E+00 1.20E-03 1.10E-02 5 61 "ATP2B4,UHMK1,POU2F1,OCIAD1,IVNS1ABP" MicroRNA hsa-miR-1281:mirSVR_highEffct hsa-miR-1281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.67E-04 1.00E+00 1.20E-03 1.10E-02 6 92 "MSH2,NFATC4,LDB2,NGDN,MARVELD2,DRC1" MicroRNA hsa-miR-5583-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.67E-04 1.00E+00 1.20E-03 1.10E-02 6 92 "DDX55,CCNB1,LYSMD3,MBNL2,LRCH1,LOX" MicroRNA hsa-miR-411-5p.1:TargetScan hsa-miR-411-5p.1 TargetScan 6.67E-04 1.00E+00 1.20E-03 1.10E-02 6 92 "ADORA1,ATP2B4,MPHOSPH8,FBXL5,KLHL3,FNIP1" MicroRNA hsa-miR-3196:mirSVR_lowEffct hsa-miR-3196:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.68E-04 1.00E+00 1.20E-03 1.10E-02 17 602 "ACOX3,EP400,CARMIL3,AMDHD1,WDFY2,PIK3C2B,THTPA,NCOR2,RNF31,POLR1D,PCGF3,TACC3,ZNF274,SLC7A8,NPL,FCRL6,TMEM178A" MicroRNA hsa-miR-518b:mirSVR_highEffct hsa-miR-518b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.83E-04 1.00E+00 1.22E-03 1.12E-02 8 166 "ZNF664,LOC439933,WDR1,DNMT3A,DLEU1,ZCCHC8,FBXO11,LPIN1" MicroRNA hsa-miR-620:PITA hsa-miR-620:PITA_TOP PITA 6.83E-04 1.00E+00 1.22E-03 1.12E-02 8 166 "SEMA6A,STARD13,CDK17,MEMO1,MBNL2,NR5A2,KHNYN,RIMBP2" MicroRNA hsa-miR-1270:PITA hsa-miR-1270:PITA_TOP PITA 6.83E-04 1.00E+00 1.22E-03 1.12E-02 8 166 "SEMA6A,STARD13,CDK17,MEMO1,MBNL2,NR5A2,KHNYN,RIMBP2" MicroRNA hsa-miR-199a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 6.83E-04 1.00E+00 1.22E-03 1.12E-02 8 166 "PDE4D,PTGS2,CEP120,DRAM1,SLC8A1,SULT1E1,ZBTB37,ZNF544" MicroRNA hsa-miR-3135b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.92E-04 1.00E+00 1.24E-03 1.13E-02 13 394 "ABL2,MMP17,THAP6,COPA,HEATR5A,PIGG,SBNO1,ARSK,SPON2,TEP1,GRSF1,GPR161,TXK" MicroRNA hsa-miR-222-3p:Functional MTI Functional MTI miRTarbase 6.92E-04 1.00E+00 1.24E-03 1.13E-02 13 394 "MAP1B,ATP7B,CAST,CDK18,PIWIL1,POLE,C12orf65,ZFYVE16,SMC6,RNF4,FOXO1,ZBTB37,KIT" MicroRNA hsa-miR-502-5p:PITA hsa-miR-502-5p:PITA_TOP PITA 6.98E-04 1.00E+00 1.25E-03 1.14E-02 7 128 "CARMIL3,RILPL1,UHMK1,NCOR2,TGM1,RIMBP2,UBE2K" MicroRNA "CCAGGGG,MIR-331:MSigDB" "CCAGGGG,MIR-331:MSigDB" MSigDB 7.07E-04 1.00E+00 1.26E-03 1.16E-02 6 93 "SEMA6A,SNX17,NBEA,KHNYN,NSD2,PABPN1" MicroRNA hsa-miR-194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.07E-04 1.00E+00 1.26E-03 1.16E-02 6 93 "UHMK1,CHD1,DNMT3A,ELF1,KDM5B,KMT5A" MicroRNA hsa-miR-510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.10E-04 1.00E+00 1.27E-03 1.16E-02 8 167 "MAP1B,SPATA18,CLIP4,LATS2,ARSK,UBC,SPTSSA,SPATA13" MicroRNA "GACAGGG,MIR-339:MSigDB" "GACAGGG,MIR-339:MSigDB" MSigDB 7.18E-04 1.00E+00 1.28E-03 1.17E-02 5 62 "NOVA1,NRXN1,FLT1,KDM5B,NFASC" MicroRNA hsa-miR-658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.39E-04 1.00E+00 1.32E-03 1.21E-02 8 168 "MDM4,RILPL1,FAM163A,GNPTAB,NCOR2,CCDC38,FNIP1,HSP90B1" MicroRNA hsa-let-7f-5p:Functional MTI Functional MTI miRTarbase 7.42E-04 1.00E+00 1.33E-03 1.21E-02 13 397 "MDM4,SLC5A6,BRI3BP,CEP135,SNX17,CEP120,MTX3,TBC1D19,PCGF3,TOMM40L,POTEM,ZBTB37,STRN" MicroRNA hsa-miR-4436b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.48E-04 1.00E+00 1.33E-03 1.22E-02 6 94 "CDKL2,VCAN,NOS1AP,ZNF419,UGT2A1,ZNF84" MicroRNA hsa-miR-29c-3p:Functional MTI Functional MTI miRTarbase 7.49E-04 1.00E+00 1.34E-03 1.22E-02 10 254 "SNX24,FAM193A,GAS2L3,DNMT3A,REST,KDM5B,KMT5C,TDG,HMGCR,LOX" MicroRNA hsa-miR-760:PITA hsa-miR-760:PITA_TOP PITA 7.50E-04 1.00E+00 1.34E-03 1.22E-02 9 210 "ATP2B4,BCL2L2,ATAD2B,FAM172A,PLEKHA6,CCDC88A,KDM3B,UBE2K,LMNB1" MicroRNA hsa-miR-25-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.50E-04 1.00E+00 1.34E-03 1.22E-02 9 210 "MDM4,HOMEZ,RILPL1,GNPTAB,NCOR2,FAM228A,CCDC38,FNIP1,HSP90B1" MicroRNA hsa-miR-1227-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.75E-04 1.00E+00 1.38E-03 1.27E-02 9 211 "MDM4,NOP14,RILPL1,MTX3,MARVELD2,CCDC38,POTEM,MRPS14,GUF1" MicroRNA hsa-miR-5096:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.90E-04 1.00E+00 1.41E-03 1.29E-02 11 302 "ATP1A2,AKAP6,HEATR5A,NGDN,DMXL1,FNIP1,SH3BP2,FAM114A1,LILRB1,ZBTB37,GTF2H3" MicroRNA hsa-miR-6073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.90E-04 1.00E+00 1.41E-03 1.29E-02 6 95 "HECTD1,MTX3,SLC35F6,PSME4,IL6ST,IRF1" MicroRNA hsa-miR-887:mirSVR_highEffct hsa-miR-887:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.90E-04 1.00E+00 1.41E-03 1.29E-02 6 95 "MDM4,ASTN1,STARD13,NCOR2,GUF1,IRF1" MicroRNA hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA_TOP PITA 7.90E-04 1.00E+00 1.41E-03 1.29E-02 6 95 "RAN,MEMO1,FOXO1,FBXO11,METAP2,RIMBP2" MicroRNA hsa-miR-665:PITA hsa-miR-665:PITA_TOP PITA 8.01E-04 1.00E+00 1.43E-03 1.31E-02 9 212 "NEDD8,KIRREL1,ETF1,TOMM40L,FGF9,KIF21B,PDS5B,PCDH17,KHNYN" MicroRNA hsa-miR-183-5p:Functional MTI Functional MTI miRTarbase 8.08E-04 1.00E+00 1.44E-03 1.32E-02 12 351 "MDM4,ATP6V1G3,MSH2,CCNB1,PIGG,LATS2,TRIM28,SUCO,FOXO1,SFSWAP,ERBIN,KIF2A" MicroRNA hsa-miR-4283:mirSVR_highEffct hsa-miR-4283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.28E-04 1.00E+00 1.47E-03 1.35E-02 12 352 "SLC5A6,TAPT1,RNF4,TRIM28,KLHL12,FLT1,CYP1B1-AS1,MYO16,NFASC,ZNF544,IL25,RMST" MicroRNA hsa-miR-4736:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.29E-04 1.00E+00 1.47E-03 1.35E-02 8 171 "MATN3,CD84,CFL2,TBC1D4,ARSK,ETF1,DLEU1,ARL6IP4" MicroRNA hsa-miR-4804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-04 1.00E+00 1.47E-03 1.35E-02 5 64 "TMEM33,UTP15,ATP6V0A2,KLF12,IL6ST" MicroRNA "AAGTCCA,MIR-422A:MSigDB" "AAGTCCA,MIR-422A:MSigDB" MSigDB 8.30E-04 1.00E+00 1.47E-03 1.35E-02 5 64 "ZNF664,ARGLU1,FOXG1,UHRF1BP1L,NSD2" MicroRNA hsa-miR-3156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-04 1.00E+00 1.47E-03 1.35E-02 5 64 "SLC5A8,PCSK1,CEP120,RABGAP1L,FAM151B" MicroRNA hsa-miR-6740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-04 1.00E+00 1.47E-03 1.35E-02 5 64 "PRKD1,FCGR3B,SDC1,ERBIN,ZNF550" MicroRNA "AAGTCCA,MIR-422B:MSigDB" "AAGTCCA,MIR-422B:MSigDB" MSigDB 8.30E-04 1.00E+00 1.47E-03 1.35E-02 5 64 "ZNF664,ARGLU1,FOXG1,UHRF1BP1L,NSD2" MicroRNA hsa-miR-496.2:TargetScan hsa-miR-496.2 TargetScan 8.37E-04 1.00E+00 1.49E-03 1.36E-02 7 132 "MPZL1,PCSK1,PDE4D,GPR180,RGS4,METAP2,FAM49A" MicroRNA hsa-miR-1273g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.52E-04 1.00E+00 1.51E-03 1.38E-02 15 507 "CAD,CDKL2,CAMK4,RILPL1,FAM163A,UBXN2A,NOS1AP,FCRL2,OCIAD1,MTX3,ZNF419,CCDC38,PAICS,UBC,LETM1" MicroRNA hsa-miR-335-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.55E-04 1.00E+00 1.52E-03 1.39E-02 11 305 "CACNA1E,CDKL2,EPGN,VCAN,DMXL1,TMEM33,PCGF3,FAM114A1,LILRB1,COMMD6,KCNT2" MicroRNA hsa-miR-612:PITA hsa-miR-612:PITA_TOP PITA 8.56E-04 1.00E+00 1.52E-03 1.39E-02 9 214 "APBB2,MYBPC1,NEDD8,PDE4D,CSNK1G3,RGS4,NR5A2,JPH4,KLF12" MicroRNA hsa-miR-1178:PITA hsa-miR-1178:PITA_TOP PITA 8.61E-04 1.00E+00 1.52E-03 1.40E-02 8 172 "ATAD2B,CLOCK,SREK1,G3BP2,LATS2,MAEA,RIMBP2,ZBTB41" MicroRNA hsa-miR-4668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.61E-04 1.00E+00 1.52E-03 1.40E-02 8 172 "FBRSL1,PIK3C2B,CLIP1,SLC8A1,SLC15A4,METAP2,DCP2,CENPH" MicroRNA hsa-miR-517c:mirSVR_highEffct hsa-miR-517c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.69E-04 1.00E+00 1.54E-03 1.41E-02 10 259 "SMIM14,HOMER1,C12orf65,GUSBP3,FCAR,NDUFAF7,FMO1,EFR3B,NPHS2,LMNB1" MicroRNA hsa-miR-4794:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.75E-04 1.00E+00 1.55E-03 1.42E-02 7 133 "PIWIL1,SMIM14,SLC35F6,ZNF419,ARSK,ZCCHC8,ZNF324B" MicroRNA hsa-miR-3925-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.75E-04 1.00E+00 1.55E-03 1.42E-02 7 133 "POLE,PRKD1,SREK1,ZNF667,KDM5B,TGFBI,SPATA13" MicroRNA hsa-miR-664a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.75E-04 1.00E+00 1.55E-03 1.42E-02 7 133 "PIWIL1,SMIM14,SLC35F6,ZNF419,ARSK,ZCCHC8,ZNF324B" MicroRNA hsa-miR-134:PITA hsa-miR-134:PITA_TOP PITA 8.75E-04 1.00E+00 1.55E-03 1.42E-02 7 133 "SLC4A4,CSNK1G3,RAN,ETF1,MYT1L,ADGRL3,EML4" MicroRNA hsa-miR-1263:PITA hsa-miR-1263:PITA_TOP PITA 8.82E-04 1.00E+00 1.56E-03 1.43E-02 6 97 "ARHGAP5,NCOA1,PCDH9,B3GLCT,FBXO11,PSME4" MicroRNA hsa-miR-411-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.85E-04 1.00E+00 1.56E-03 1.43E-02 9 215 "MAP1B,CCNB1IP1,ATP1A2,AKAP6,HEATR5A,DMXL1,GABRB1,GTF2H3,PGAM5" MicroRNA hsa-miR-572:PITA hsa-miR-572:PITA_TOP PITA 8.89E-04 1.00E+00 1.57E-03 1.44E-02 3 17 "PITPNM2,BCL2L2,PPARGC1A" MicroRNA hsa-miR-4318:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.91E-04 1.00E+00 1.57E-03 1.44E-02 5 65 "THAP6,FAM163A,RB1,MSH6,AP4S1" MicroRNA hsa-miR-4450:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.91E-04 1.00E+00 1.57E-03 1.44E-02 5 65 "PPFIA4,KLHL3,TRIM28,SPON2,HSP90B1" MicroRNA hsa-miR-1288:PITA hsa-miR-1288:PITA_TOP PITA 8.91E-04 1.00E+00 1.57E-03 1.44E-02 5 65 "NEDD8,FOXO1,FBXO11,NMNAT2,ANO4" MicroRNA hsa-miR-6849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.92E-04 1.00E+00 1.57E-03 1.44E-02 19 731 "SMIM15,ADD1,MMP17,CCNB1,PIGR,UBXN2A,FCRL2,MTX3,FAM129A,ZNF329,MARVELD2,ELOVL7,PAICS,MCCC2,COX18,GRSF1,ATP6V0A2,UBC,LETM1" MicroRNA hsa-miR-4305:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.07E-04 1.00E+00 1.60E-03 1.47E-02 4 38 "UHMK1,SLC5A8,SREK1,KIT" MicroRNA "GACAATC,MIR-219:MSigDB" "GACAATC,MIR-219:MSigDB" MSigDB 9.14E-04 1.00E+00 1.61E-03 1.48E-02 7 134 "NCOA1,PDE4D,PDGFRA,ELOVL7,PCDH17,PPARGC1A,DCP2" MicroRNA "TCATCTC,MIR-143:MSigDB" "TCATCTC,MIR-143:MSigDB" MSigDB 9.14E-04 1.00E+00 1.61E-03 1.48E-02 7 134 "MAP1B,AKAP6,STRN3,CSNK1G3,DNMT3A,PSME4,NUAK2" MicroRNA hsa-miR-4264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.30E-04 1.00E+00 1.64E-03 1.50E-02 6 98 "PKP1,THAP6,GNPTAB,DLEU1,FGF9,KIF21B" MicroRNA hsa-miR-1289:PITA hsa-miR-1289:PITA_TOP PITA 9.30E-04 1.00E+00 1.64E-03 1.50E-02 6 98 "XPR1,STRN3,EFNA5,RNF4,KDM5B,DOCK9" MicroRNA hsa-miR-661:Functional MTI Functional MTI miRTarbase 9.38E-04 1.00E+00 1.65E-03 1.51E-02 14 459 "MDM4,CAD,PIGR,UBXN2A,FCRL2,KLHL3,MTX3,SLC35F6,PCBD2,PAICS,MCCC2,COX18,UBC,LETM1" MicroRNA hsa-miR-454*:mirSVR_highEffct hsa-miR-454*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.50E-04 1.00E+00 1.67E-03 1.53E-02 11 309 "MRPL57,HOMER1,COG3,KDM3B,ADAM17,C5orf56,COP1,TDG,TGM1,TMPO,TTC41P" MicroRNA hsa-miR-34a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.51E-04 1.00E+00 1.67E-03 1.53E-02 19 735 "MAP1B,MDM4,BIRC6,MCFD2,APAF1,NCOA1,B4GALT3,CAD,PDGFRA,POU2F1,CLOCK,PRKD1,G3BP2,CIDEB,ACSL6,TCF7,KLF12,KIF2A,KIT" MicroRNA hsa-miR-886-5p:mirSVR_highEffct hsa-miR-886-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.55E-04 1.00E+00 1.68E-03 1.54E-02 5 66 "WDR19,MPHOSPH8,CCDC92,CIDEB,KHNYN" MicroRNA hsa-miR-3942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.55E-04 1.00E+00 1.68E-03 1.54E-02 7 135 "PCSK1,WDFY2,MATR3,KLHL12,SUCO,UFM1,ZBTB49" MicroRNA hsa-miR-514:PITA hsa-miR-514:PITA_TOP PITA 9.62E-04 1.00E+00 1.69E-03 1.55E-02 8 175 "MCFD2,NCOA1,PCCA,PIK3C2B,RELL1,SUCO,INSM2,ZBTB41" MicroRNA hsa-miR-657:PITA hsa-miR-657:PITA_TOP PITA 9.62E-04 1.00E+00 1.69E-03 1.55E-02 8 175 "MAP1B,MCC,SLC4A4,NRXN1,TMEM161B,NBEA,CCDC92,MYT1L" MicroRNA hsa-miR-21:PITA hsa-miR-21:PITA_TOP PITA 9.76E-04 1.00E+00 1.71E-03 1.57E-02 10 263 "FCHO2,CFL2,ATAD2B,LRRTM2,FBXO11,G2E3,XPO4,TGFBI,ZNF10,ZBTB41" MicroRNA hsa-miR-3611:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.81E-04 1.00E+00 1.72E-03 1.58E-02 6 99 "PDE4D,TLR6,PCGF3,ZBTB37,TFDP1,HGFAC" MicroRNA hsa-miR-455-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.81E-04 1.00E+00 1.72E-03 1.58E-02 6 99 "PCCA,PLEKHA6,ZNF544,NCSTN,NT5C1B,NT5C1B-RDH14" MicroRNA hsa-miR-381-3p:Functional MTI Functional MTI miRTarbase 9.97E-04 1.00E+00 1.75E-03 1.60E-02 7 136 "ARL1,NFKBIA,BRI3BP,OCIAD1,UTP15,NDUFAF7,MSH6" MicroRNA hsa-miR-6731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-03 1.00E+00 1.76E-03 1.61E-02 4 39 "SYT2,GABRB1,ADAM17,PPIP5K2" MicroRNA hsa-miR-6134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-03 1.00E+00 1.76E-03 1.61E-02 12 360 "MCFD2,NOP14,PPP1R12B,SLC5A6,CCNB1,CFL2,EPN1,ZNF329,MARVELD2,TBC1D19,IGF1,ZDHHC20" MicroRNA "AAGCACT,MIR-520F:MSigDB" "AAGCACT,MIR-520F:MSigDB" MSigDB 1.01E-03 1.00E+00 1.77E-03 1.62E-02 9 219 "NOVA1,UHMK1,CFL2,NTN4,MBNL2,FLT1,BAZ1A,IL6ST,ZBTB41" MicroRNA hsa-miR-4699-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-03 1.00E+00 1.79E-03 1.64E-02 5 67 "MCFD2,CAD,G3BP2,MTX3,FAM129A" MicroRNA hsa-miR-149-5p:TargetScan hsa-miR-149-5p TargetScan 1.03E-03 1.00E+00 1.80E-03 1.65E-02 12 361 "ADD1,MSH2,PPP1R12B,BCL2L2,CDK17,PDGFRA,PGGT1B,KLHL3,PLEKHA6,HMGCR,KIF2A,LOX" MicroRNA hsa-miR-3131:mirSVR_highEffct hsa-miR-3131:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-03 1.00E+00 1.81E-03 1.66E-02 6 100 "ITGBL1,LATS2,ETF1,RBKS,RIMBP2,CCDC169" MicroRNA hsa-miR-16-1-3p:Functional MTI Functional MTI miRTarbase 1.03E-03 1.00E+00 1.81E-03 1.66E-02 6 100 "NLN,ITSN2,MATR3,WDCP,IKBIP,XPO4" MicroRNA hsa-miR-450a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-03 1.00E+00 1.81E-03 1.66E-02 6 100 "MDM4,USP44,SPON2,NMNAT2,FAM151B,FAM49A" MicroRNA hsa-miR-4428:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-03 1.00E+00 1.82E-03 1.67E-02 7 137 "TOGARAM2,COCH,SPON2,MRPS27,GRSF1,SLC7A8,ZNF84" MicroRNA hsa-miR-7156-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-03 1.00E+00 1.82E-03 1.67E-02 7 137 "SEMA6A,MYBPC1,ZNF664,CSNK1G3,ARGLU1,LAD1,LMNB1" MicroRNA hsa-miR-490-3p:PITA hsa-miR-490-3p:PITA_TOP PITA 1.04E-03 1.00E+00 1.82E-03 1.67E-02 7 137 "RALGAPA1,CHD1,ETF1,VEZT,PCDH17,TMED2,UBE2K" MicroRNA hsa-miR-383:PITA hsa-miR-383:PITA_TOP PITA 1.04E-03 1.00E+00 1.82E-03 1.67E-02 7 137 "DCLK1,STRN3,SACS,FGF9,PLEKHA6,PCDH17,IRF1" MicroRNA hsa-miR-873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-03 1.00E+00 1.86E-03 1.70E-02 10 266 "CAD,PDE6B,EGLN3,MARVELD2,PCBD2,SH3BP2,XPO4,HAL,HPCAL1,DCP2" MicroRNA hsa-miR-4756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 7 138 "HOMEZ,POU2F1,ATG10,RNASEL,TCTN2,FAM81B,SDC1" MicroRNA "GAGCCAG,MIR-149:MSigDB" "GAGCCAG,MIR-149:MSigDB" MSigDB 1.09E-03 1.00E+00 1.90E-03 1.74E-02 7 138 "ADD1,BCL2L2,CDK17,PDGFRA,KLHL3,TNFRSF19,PLEKHA6" MicroRNA hsa-miR-621:PITA hsa-miR-621:PITA_TOP PITA 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "SLC5A8,DCLK1,CFL2,GPR180,NRXN1,SLC12A2" MicroRNA hsa-miR-1206:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "MYBPC1,TOGARAM2,FOXG1,ACSL6,NSD2,ZNF470" MicroRNA hsa-miR-1306:mirSVR_highEffct hsa-miR-1306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "GLT1D1,DNMT3A,BRD8,ZNF544,ADGRL3,GUF1" MicroRNA hsa-miR-6781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "MAP1B,CD84,DDX51,POC5,STARD4,KCNJ9" MicroRNA hsa-miR-3617-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "MAP1B,NLN,TTC37,REST,LIMCH1,IQGAP2" MicroRNA hsa-miR-2682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 6 101 "MAP1B,CD84,DDX51,POC5,STARD4,KCNJ9" MicroRNA hsa-miR-505-3p.2:TargetScan hsa-miR-505-3p.2 TargetScan 1.09E-03 1.00E+00 1.90E-03 1.74E-02 10 267 "PDE4D,NUP37,DMXL1,OCIAD1,RASA1,ARGLU1,REST,ELK3,DNAJC27,SCYL2" MicroRNA hsa-miR-4646-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.09E-03 1.00E+00 1.90E-03 1.74E-02 5 68 "UBXN2A,PACRGL,KLHL12,ATP6AP1L,MRPS27" MicroRNA hsa-miR-6089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-03 1.00E+00 1.94E-03 1.77E-02 8 179 "CAD,CCNB1,PIGR,DTD2,STX2,UHRF1BP1L,COX18,ZNF324B" MicroRNA hsa-miR-208a:mirSVR_highEffct hsa-miR-208a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.11E-03 1.00E+00 1.94E-03 1.77E-02 8 179 "UVSSA,NFKBIA,ZNF595,FCRL5,ARGLU1,DLEU1,FOXG1,DOCK9" MicroRNA hsa-miR-214-5p:TargetScan hsa-miR-214-5p TargetScan 1.13E-03 1.00E+00 1.97E-03 1.80E-02 7 139 "CBLN3,PDGFRA,CFL2,FAM169A,PCGF3,CNTN2,KLF12" MicroRNA hsa-miR-6879-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-03 1.00E+00 1.97E-03 1.80E-02 7 139 "ABL2,NLN,NRL,STRN3,PIGG,BRMS1L,SLC22A4" MicroRNA hsa-miR-106b*:mirSVR_highEffct hsa-miR-106b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.15E-03 1.00E+00 1.99E-03 1.82E-02 6 102 "FBXL5,LOC439933,RNF212,AP4S1,VRK2,TMEM178A" Drug ctd:C029790 "2,2',3',4,4',5-hexachlorobiphenyl" CTD 2.88E-22 9.36E-18 9.36E-18 1.03E-16 164 1885 "MAG,SDE2,MAP6,ACHE,ACLY,APC2,MBP,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,RTN1,DSCAML1,SORCS1,FCGR1A,CHST15,DRAXIN,SNX32,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,MOG,SOX6,FOXM1,AMPH,CDC42BPA,ANK1,ANK3,ITSN1,ANXA7,SH3GL2,PPM1E,GAS7,CLSTN1,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,SLCO1A2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,SNAP25,ATM,ATP1A2,NRG3,ATP1A3,ATP2B2,USP33,KIF21B,NMNAT2,KIF1B,NASP,NCAM1,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,GNAS,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GRIN1,GPR88,VWCE,OMG,OPCML,PTPN5,TIE1,NEURL1,PC,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,DLGAP3,CPT1C,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,ACBD5,MFSD4A,POU3F2,ETNPPL,PTPA,MICAL2,PLCH2,PRKACB,DOCK7,CALY,PRKCG,ARHGEF4,CTNND1,NRSN1,BRINP3,PSD,SYTL2,DPYSL5,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,RGMA,MAGI2,KCND3,SV2A,NTM,AK5,KCNMA1,NAV2,KCNQ2,DLG2,PYGM,RAB5B,TMEM255A,DNM2,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,PIANP,EFNA3,SLC4A10,EPB41L1" Drug ctd:D003042 Cocaine CTD 1.54E-19 5.01E-15 2.50E-15 2.75E-14 124 1317 "ABAT,MAP6,MBP,SYT9,RCSD1,ACTN2,EYA1,RTKN,NDRG2,CLIP1,ADCY2,SLITRK1,PNMA8B,ADORA1,AGT,PLA2G6,LRRC7,SEMA6A,C1QTNF4,HPCAL4,MOBP,SEMA6C,ANXA7,SYBU,SLC1A2,PKNOX2,ARHGAP5,CCDC88A,SHANK2,SLC14A1,CSPG5,TAGLN3,SORCS3,ADGRA1,ATM,SNCB,ATP1A3,GABBR1,SON,GAD2,MYH7,ARPP21,ERBIN,GFAP,KIRREL3,GJB1,ARHGEF7,SYT4,NKX2-2,SEMA4A,ADGRL3,GPM6A,GPM6B,ATF7,NPPA,CAMK2A,DDR2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIN1,GPR88,GRM3,TF,CCKBR,INA,GUCY1A1,AIFM1,CD81,TNFRSF1B,PCDH8,SEZ6L,TPM3,PCSK2,PDYN,FNDC5,CHRM4,CHRNB2,GDAP1L1,SEMA5B,UBTF,TJP2,NECAB2,RNF14,SNCAIP,TENM4,NCAN,CALY,PRKCG,PRKCZ,CTNND2,MAPK8,MAPK10,ZBTB16,ACY3,ANKS1B,JAKMIP2,PMEPA1,ELMO1,PRDM2,KCNA2,KCNA6,KCND3,KCNJ4,KCNJ10,KCNJ11,SNX27,DLG2,CAB39L,DNM2,SLC17A6,RASGRF1,ABCC9,CRTAC1,CAMK1G,EEF1A2,PIANP,EFNA3,RBM12,SLC4A10,BSCL2,BAALC" Drug CID005183170 AC1NPPZW Stitch 3.08E-16 9.99E-12 3.33E-12 3.65E-11 28 103 "ASIC1,KCNIP2,SCN4B,FGF14,ASIC4,ANK2,ANK3,FOLH1,BCAN,SCN3B,NEUROD1,ZEB1,INA,ASIC3,SERPINE2,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,NTM,KCNJ10,KCNK2,PCDH15,NAV2,ABI1,ABI2" Drug ctd:C496932 panobinostat CTD 6.43E-15 2.09E-10 5.22E-11 5.72E-10 114 1335 "ABAT,MAP6,ASIC1,TMEM74,ADGRV1,WLS,SLC25A25,RTN1,ADCYAP1R1,AMER2,CHST15,SCN4B,C1QTNF4,ELMOD1,USP28,GAS7,NLGN1,SFMBT2,LRRC55,PKNOX2,ARHGAP5,DACH2,ASCL1,SCG3,CSPG5,SLIT1,ASTN1,SNAP25,TNIK,SOX10,GAD2,NMNAT2,SALL3,DNER,NFASC,LMO3,COLGALT2,STOX1,SMOC1,NELL1,AJAP1,FAM168A,GLS,SYT4,ASTN2,POPDC3,DCLK2,GNAS,CNTN2,ADGRL3,WWC1,PRUNE2,FAM69C,CACNB2,ZEB1,GRIA1,GRIK3,GRM3,OPCML,CCKBR,PTPN5,GUCY1A1,KCNK10,PAX6,IGSF21,PCDH8,CDH8,CDH10,DCLK1,PDYN,ZMYND8,FNDC5,ADGRG1,SCRG1,CHGA,NRXN2,NEGR1,CCDC136,CNTN1,CELF5,PRRX1,NSD2,FAT3,CNRIP1,FEZ1,KIAA1755,CTNND2,MAPK10,HES5,ZBTB16,TOX,SYTL2,ANKS1B,ZNF385B,PMEPA1,LRP8,RGMA,MAGI2,OLFM3,KCNC1,PTPRO,RABGAP1L,ARNT2,KCNK1,KCNN3,PID1,FAM13C,L1CAM,ST8SIA3,RFX4,FGFBP3,LPAR6,RASGRP2,SEZ6" Drug ctd:C042720 mercuric bromide CTD 1.30E-14 4.24E-10 8.47E-11 9.29E-10 98 1077 "MAP6,ASIC1,TMEM74,CNTNAP3,SYT9,F3,ADCY2,SLITRK1,ADCYAP1R1,SORCS1,AMER2,SEMA6A,ELMOD1,SOX6,ANK1,USP28,APBA2,CACHD1,SYBU,SHTN1,SLC1A2,BCO1,PKNOX2,GPR153,CSPG5,ASTN1,PALLD,SOX1,TNIK,JPH4,SALL3,LHFPL4,NFASC,NCAM1,LMO3,COLGALT2,STOX1,SMOC1,AJAP1,GLS,DCLK2,GNAS,ROBO3,CNTN2,KLHL4,PRUNE2,GPM6A,GPM6B,FAM69C,CACNB2,DDR2,CCKBR,KCNK10,PAX6,REPS2,IGSF21,PCDH8,PCDH9,CDH10,HRH3,PDE4B,FNDC5,JAM2,GDAP1L1,TJP2,CCDC136,CELF5,POU3F2,SNCAIP,FEZ1,OSBPL3,NCAN,DOCK7,CTNND2,MAPK10,HES5,ZBTB16,TOX,ZNF385B,DNAJC6,CADM2,RGMA,OLFM3,KCNK1,KCNQ2,PYGM,CAB39L,GNE,FAM13C,DTNA,SLC6A15,RET,RFX4,RGS7,SFXN5,LMO1,LPAR6,SEZ6" Drug ctd:C410127 PCB 180 CTD 2.59E-14 8.41E-10 1.34E-10 1.46E-09 132 1683 "SERPINA3,MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ANK3,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,SLCO1A2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,TMEM108,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ACSBG1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,KLHL4,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,GRIA4,RFFL,GRIN1,GPR88,GRM3,VWCE,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,DLGAP3,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,HES5,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,AK5,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10,EPB41L1" Drug CID000001727 4-AP Stitch 3.26E-14 1.06E-09 1.34E-10 1.46E-09 41 258 "ACHE,KCNIP2,ADORA1,ADORA3,SCN4B,MTR,ATP1A2,ATP1A3,SCN3B,MYBPC1,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,GUCY1A2,KCNK10,ASIC3,CHRM1,UBTF,PRKCG,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,EPB41" Drug ctd:D019422 Dietary Sucrose CTD 3.53E-14 1.15E-09 1.34E-10 1.46E-09 89 946 "TTYH1,ACLY,APC2,RCSD1,ADCY2,SLITRK1,CDC7,ERMN,GRAMD1B,SNX32,BBOX1,ELMOD1,SELL,JAKMIP3,ST8SIA1,RPH3A,MT3,NSG2,DACH2,LGI3,DNAH17,DLL3,BRINP2,SORCS3,B3GAT1,GABBR1,SCN3B,SOX10,MYH7,LHFPL4,NFASC,GPR162,RCOR2,NELL1,MLC1,MMD2,ADGRL3,CACNA1E,NPPA,DIRAS1,GPR26,HAP1,CAMK2A,GRIN1,OLR1,TLL2,TNR,PCDH8,HRH3,PIRT,TMPRSS5,PFKFB3,GDAP1L1,FADS2,SULT4A1,CELF5,BEST1,ATCAY,BTBD17,MFSD4A,POU3F4,TENM4,CSF3R,RIMS4,PLD5,SLC45A1,IGSF1,FAM131B,NOS1AP,TOX,CDH20,KCNA6,PTPRZ1,KCNJ4,KCNJ9,ARNT2,KCNK2,KCNMA1,KCNQ2,CALN1,SLC25A18,DBX2,CAMK1G,RGS7,VANGL2,SLC39A12,CBLN2,RAVER2,PRRT4" Drug ctd:C009407 "2,5,2',5'-tetrachlorobiphenyl" CTD 3.70E-14 1.20E-09 1.34E-10 1.46E-09 132 1691 "MAP6,ACHE,APC2,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,RYR1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ANK3,CNIH2,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,PRLHR,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,GRM3,OMG,OPCML,PTPN5,TIE1,TMEM9,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,RGS6,FEZ2,MICAL2,PLCH2,DOCK7,CALY,ARHGEF4,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,MAGI2,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,DNM2,SLC17A6,SUSD4,DSCAM,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug CID000004376 N-methyl-DL-aspartic acid Stitch 5.36E-14 1.74E-09 1.74E-10 1.91E-09 70 655 "EPS8,ACHE,ADGRV1,RYR1,ADORA1,ADORA3,SCN4B,LRRC7,FOLH1,APBA2,NLGN1,SLC1A2,RPH3A,SLC1A7,SLC6A9,SHANK2,B3GAT1,NRG3,FYN,SCN3B,SOX10,GAD2,NCAM1,GFAP,GLS,GNAS,CACNA1A,CACNA1E,CACNB2,NRGN,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,GUCY1A2,AIFM1,PAH,MAGI1,PDE2A,PDYN,ASIC3,CHRM1,CHRNB2,CAMKV,PIK3CD,PRKACB,PRKCG,PKN2,PRKCZ,NOS1AP,PTCH1,LRP8,MAGI2,KCNA1,KCNA4,DLG2,DLG3,RAB5B,SLC17A6,RASGRF1,CAMK1G,NUP214,CACNG7" Drug CID000005070 riluzole Stitch 6.31E-14 2.05E-09 1.86E-10 2.04E-09 33 174 "ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC1A2,NRG3,SCN3B,NFASC,GFAP,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,ZFP91,KCNK10,ASIC3,STMN4,KCNA4,KCNC1,KCND3,KCNK1,KCNK2,KCNN3,CACNG7" Drug ctd:C081766 "2,4,4'-trichlorobiphenyl" CTD 7.63E-14 2.48E-09 2.06E-10 2.26E-09 117 1437 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug ctd:C009828 "2,4,5,2',5'-pentachlorobiphenyl" CTD 1.36E-13 4.41E-09 3.39E-10 3.72E-09 118 1467 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,RYR1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SHANK2,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,OMG,OPCML,TIE1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug CID000005413 tetraethylammonium Stitch 1.86E-13 6.05E-09 4.32E-10 4.74E-09 38 236 "ASIC1,ACHE,SCN4B,MTR,ATP1A2,ATP1A3,SCN3B,MYBPC1,NCDN,CACNB2,INA,GUCY1A2,KCNK10,HRH3,ASIC3,CHRM1,SLC22A6,NRXN2,UBTF,PRKACB,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2" Drug CID000000611 glutamate Stitch 2.45E-13 7.94E-09 5.29E-10 5.81E-09 88 962 "ABAT,ASIC1,MAPT,ACHE,ADAR,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,SCN4B,SEMA6A,ACTL6B,FOXM1,FOLH1,AQP4,SLC1A2,SLC1A6,SLC1A7,SLC6A9,CSPG5,MTR,B3GAT1,ALDH4A1,SNAP25,ATP1A2,SCN3B,SOX10,GAD2,NMNAT2,GART,CPLX2,DNER,NPAS3,NFASC,GFAP,GLS,SYT4,GNAS,CACNA1A,CACNA1E,CACNB2,NRGN,AZIN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,P2RX7,AIFM1,ZFP91,PAH,PC,TPM3,PDYN,CHI3L2,ASIC3,CHRM1,CHRNB2,SULT4A1,ATCAY,ETNPPL,CALY,PRKCG,PKN2,PRKCZ,MAPK10,KLK6,ACY3,STMN4,KCNA1,KCNA2,KCNA4,SV2A,KCNJ10,KCNMA1,DLG2,SLC17A6,SLC25A18,EEF1A2,CACNG7,OLIG2" Drug ctd:C030370 "2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone" CTD 7.03E-13 2.28E-08 1.43E-09 1.57E-08 44 320 "MAG,NDRG2,TUBB4A,BBOX1,ANK2,RPH3A,CSPG5,SNAP25,GAD2,AHCYL1,KIF1B,LMO3,CLASP2,GFAP,CAMSAP2,MYRF,PRUNE2,TF,OPCML,CDC42,PCDH8,PCDH9,RBFOX2,TPD52,SCRG1,CHGA,PFKFB3,PLEKHB1,HNRNPK,HPCA,NRXN1,NRXN2,CNTN1,COL9A2,ETNPPL,PRKACB,CTNND2,ZBTB16,TUBB2B,SV2A,KCNQ2,RALGDS,RTN4,EPB41L1" Drug CID000020382 tetradotoxin Stitch 8.11E-13 2.63E-08 1.55E-09 1.70E-08 52 428 "ASIC1,ACHE,ADCYAP1R1,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ASIC4,FOXM1,ANK3,MTR,B3GAT1,ATP1A2,ATP1A3,SCN3B,GAD2,NKX6-2,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CCKBR,INA,GUCY1A2,P2RX7,HRH3,PDYN,NTSR2,ASIC3,CHRM1,CHRNB2,P2RY12,PRKCG,PKN2,PRKCZ,PTCH1,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCND3,KCNMA1,KCNN3" Drug CID000000119 gamma-aminobutyric acid Stitch 1.15E-12 3.73E-08 2.07E-09 2.27E-08 55 474 "ABAT,MAPT,ACHE,RYR1,ADORA1,ADORA3,AGT,SCN4B,SEMA6A,AMPH,SLC1A2,SLC1A6,SLC1A7,SLC6A9,ASCL1,B3GAT1,SNAP25,GABBR1,GAD2,GFAP,GLS,CNDP1,CACNA1A,CACNA1E,NPPA,CACNB2,ZEB1,HAP1,AZIN2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,PC,TPM3,PDYN,CHRM1,CHRNB2,SULT4A1,ETNPPL,PTCH1,STMN4,KCNA1,SV2A,KCNMA1,SLC17A6,DTNA,SLC6A15,EEF1A2,CACNG7" Drug ctd:D013759 Dronabinol CTD 3.32E-12 1.08E-07 5.67E-09 6.21E-08 82 908 "MAP6,MBP,SYT9,RTN3,ACTN2,KCNIP2,RYR1,FABP7,TUBB4A,FGF1,HPCAL4,MOBP,FOXM1,APBB1,NTNG1,BCAS1,AQP4,RPH3A,SLC6A9,NSG2,TAGLN3,ADGRA1,FYN,ARPP21,NCAM1,BCL2L2,GFAP,PHLDB1,MLC1,DCLK2,GOLGB1,ACSL6,HAP1,CAMK2A,DDR2,GRIA1,GRIK3,GPR88,TF,OPCML,GUCY1A1,NEURL1,CDC42,LGI1,TPD52,PDYN,PLEKHB1,HNRNPK,TMEFF2,HPCA,SERPINE2,NRXN1,OPALIN,CCDC136,MFSD4A,CRMP1,PPP2R5C,PPP3CB,CMTM5,PKN2,IGSF1,MAPK8,KLK6,PMEPA1,KCNA1,PTPRE,NTM,AK5,RABGAP1L,KCNMA1,SNX27,OLIG1,SLC17A6,RALGDS,RASGRF1,RTN4,L1CAM,SLC6A15,CRTAC1,ZYG11B,ST8SIA3,YY1AP1" Drug ctd:D000447 Aldehydes CTD 4.96E-12 1.61E-07 7.81E-09 8.56E-08 70 720 "ABAT,MAPT,TMEM74,SYT9,CEND1,MEG3,FAM43B,DSCAML1,SCN4B,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,CNIH2,SORBS1,SLC1A2,ZNF365,KIAA1614,SFMBT2,SLC8A2,SLN,TMEM108,TMEM151A,FYN,JPH4,TTC9B,NFASC,ALDH1L1,GFRA1,RCOR2,SEPT3,CAMTA1,WSCD1,DIRAS1,TF,OLR1,LINC00839,INA,ZDHHC22,PADI2,DCLK1,PDE2A,ARHGAP22,DUSP26,SERPINE2,NRXN2,CAMKV,NECAB2,ATCAY,BTBD17,CP,FEZ1,CHD5,RIMS4,ARHGEF4,IGSF1,RIMS3,DPYSL5,PMEPA1,CCDC3,PID1,KLRC3,TMEM255A,RAP1GAP,L1CAM,SLC6A15,RET,EEF1A2,PRRT4" Drug ctd:C046012 pentanal CTD 5.24E-12 1.70E-07 7.81E-09 8.56E-08 117 1531 "ABAT,MAPT,TMEM74,MBP,CNTNAP3,SYT9,CEND1,MEG3,FAM43B,ATAT1,DSCAML1,SCN4B,PLA2G6,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,SORBS1,BCAS1,SLC1A2,ZNF365,MIER1,SFMBT2,SLC8A2,RTP5,SLC14A1,SPHKAP,SLN,SORCS3,TMEM108,ATM,TMEM151A,ATP1A3,FYN,MEGF11,DKK3,CADM3,NMNAT2,JPH4,TTC9B,NFASC,GPR162,GFRA1,RCOR2,SEPT3,NFIA,ARHGEF7,DCLK2,CAMTA1,GOLGB1,WSCD1,DIRAS1,NRGN,GRIK2,ADAMTS8,TF,OLR1,CCKBR,LINC00839,MFSD2A,FBXL16,INA,CELF3,ZDHHC22,PADI2,PCDH9,DCLK1,PDE2A,CHI3L2,PLEKHB1,CASC2,ARHGAP22,DUSP26,DLGAP3,SERPINE2,NRXN2,CAMKV,HPR,FTO,COL9A2,NECAB2,ATCAY,BTBD17,CP,CRMP1,FEZ1,CHD5,RIMS4,PRKACB,SDC3,CMTM5,ARHGEF4,IGSF1,MAPK8,MAPK10,RIMS3,DPYSL5,ANKS1B,TUBB2B,PMEPA1,CCDC3,KCNMA1,PID1,KLRC3,TMEM255A,FAM66C,RAP1GAP,L1CAM,SLC6A15,RET,ZNF248,EEF1A2,CACNG7,PIANP,PRRT4,RASGRP2" Drug ctd:C005556 propionaldehyde CTD 5.29E-12 1.72E-07 7.81E-09 8.56E-08 141 1982 "ABAT,MAP6,MAPT,TMEM74,SYT9,CEND1,MEG3,ADGRV1,FAM43B,MRVI1,WLS,PLEKHG5,DSCAML1,SLC44A5,AGT,SCN4B,GOLGA7B,ELMOD1,HPCAL4,C1orf61,PDZD4,FOXM1,TRIM46,AMPH,PI16,CNIH2,SESN3,SORBS1,ST3GAL3,SLC1A2,ZNF365,SFMBT2,MSRA,SLC8A2,YPEL4,SHANK2,SLC14A1,SLN,TMEM108,ALDH4A1,TMEM151A,ATP1A2,FYN,PALLD,MEGF11,DKK3,MYBPC1,TNIK,NMNAT2,JPH4,TTC9B,IDI2-AS1,CPLX2,DNER,NFASC,C11orf87,ALDH1L1,GFRA1,RCOR2,KIRREL3,GJB1,SEPT3,ASTN2,KAZN,CAMTA1,UNC5D,PSRC1,WSCD1,NEU4,DIRAS1,CECR2,VWCE,TF,OLR1,LINC00839,CRB1,INA,ZDHHC22,PAX6,TNR,PADI2,DCLK1,LILRA4,PDE2A,FNDC5,GPR37L1,PLEKHB1,MS4A7,HPCA,ARHGAP22,DUSP26,SERPINE2,KIAA1549L,NRXN2,CAMKV,ANLN,CPT1C,ST8SIA5,PLXNB3,CABP1,CELF5,NECAB2,PACSIN1,ATCAY,BTBD17,MFSD4A,CP,FEZ1,CHD5,RIMS4,ARHGEF4,SLC45A1,IGSF1,CTNND2,RIMS3,SYTL2,DPYSL5,PMEPA1,ITIH2,CADM2,CNIH3,RGMA,CCDC3,KCNMA1,KCNN3,PID1,TMEM255A,SLC25A41,RAP1GAP,L1CAM,SLC6A15,CRTAC1,RET,INSYN2,EEF1A2,VANGL2,CACNG7,PIANP,FGFBP3,PRRT4,RASGRP2" Drug ctd:C015001 arsenite CTD 2.01E-11 6.53E-07 2.76E-08 3.02E-07 126 1732 "RPL38,SYNDIG1,ACTN2,NDRG2,WAC,ERMN,CHST15,GPR158,SEMA6A,SEMA6C,SFPQ,SGIP1,CDC42BPA,ANK2,FOLH1,DGKZ,DGKD,SLITRK3,BCAN,CACHD1,API5,DACH2,CADPS,TAGLN3,SORCS3,SNAP25,SNCB,TNIK,SOX5,GAD2,NMNAT2,ENKUR,GART,CPLX2,NAP1L2,LMO3,SMOC1,NELL1,NEUROD1,NKX2-2,GNAS,GNG4,ANO4,TBX15,DDR1,CACNB2,PRLHR,CLEC9A,PCDHGA3,SYT6,GRIA2,GRIA4,GRIK3,GRIN1,TF,OPCML,USP2,INA,AIFM1,ZFP91,PAX6,TNFRSF1B,PCDH8,PCDH9,CDH8,LGI1,PCSK2,CIART,CHRM1,TMEFF2,JAM2,SERPINE2,NRXN2,TJP2,ST8SIA5,PLXNB3,CNTN1,CABP1,COL9A2,SPATA6,IFFO1,NXPH1,POU3F4,KCNT2,FEZ1,VCAN,RBPJ,PKN2,NRSN1,MAPK8,MAPK10,PROX1,BRINP3,TOX,SIRPA,PTCH1,DNAJC6,ITGAV,CA10,PTHLH,ELMO1,PRTFDC1,MAGI2,STMN4,KCNA1,PTPRE,KCNC1,PTPRZ1,KCNK2,KCNQ2,PYGM,DNAH9,TMEM255A,CALN1,SLC17A6,RAP1GAP,DBX2,DTNA,ST8SIA3,EEF1A2,RNF220,VWA5A,OLIG2,TMEM100,EPB41L1,SEZ6" Drug CID000000813 potassium Stitch 2.04E-11 6.62E-07 2.76E-08 3.02E-07 86 1009 "ASIC1,KCNIP2,ADCY2,RYR1,ADORA1,ADORA3,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,BBOX1,FOXM1,ANK3,AQP4,SLC1A2,SLC1A6,SLC1A7,SLC8A2,SLC8A3,SLC14A1,NAXD,MTR,SNAP25,ATP1A2,ATP1A3,ATP2B2,SCN3B,GART,GFAP,ABCC8,GLS,OS9,NODAL,CACNA1A,CACNA1E,DDR1,NPPA,CACNB2,GRIK4,CYB561A3,GRM3,TF,LEFTY2,INA,GUCY1A2,P2RX7,KCNK10,RBFOX2,HRH3,PDE3B,ASIC3,CHRM1,CHRNB2,HPCA,PIK3CD,POU3F4,PTPA,KCNT2,PRKACB,PRKCG,PKN2,PRKCZ,KLK6,PTCH1,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,SV2A,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,DLG3,DPP6,ABCC9,RGS7,CACNG7" Drug CID000003355 flecainide Stitch 2.49E-11 8.10E-07 3.24E-08 3.55E-07 19 71 "SERPINA3,ASIC1,KCNIP2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNB2,ASIC3,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNK1,DPP6" Drug ctd:D005419 Flavonoids CTD 8.15E-11 2.65E-06 1.02E-07 1.12E-06 92 1142 "MAG,ASIC1,ACLY,KCNIP2,ADARB2,RTN1,ADCY2,ADCYAP1R1,ADD3,AGT,SCN3A,MOBP,FOXG1,SELL,SH3GL2,GAS7,CCDC80,NLGN1,BCAS1,BCO1,SLC6A9,CGREF1,SCG3,DLL3,DDX25,SNAP25,SNCB,ATP1A3,DKK3,MYH7,FXYD6,NCAM1,NELL1,SEPT3,NFIA,ABCC8,GLS,GNAS,CACNA1E,DDR1,NRGN,SYT6,GRIA1,GPR88,TF,OPCML,TGFBR3,GUCY1A2,TJP1,KCNK10,CD81,PC,CDH10,DCLK1,ZNF384,PDE1A,PHKG1,NLGN3,NEGR1,TJP2,NECAB2,SPATA6,P2RY12,POU3F2,PPP3CB,FEZ1,MAPK10,HES5,KLK6,RIMS3,DPYSL5,PTAFR,PTCH1,CEP170,CSDE1,PTPRO,SV2A,KCNJ4,KCNJ11,ARNT2,KCNN3,OLIG1,KLRC2,ABI1,ATN1,GNE,RTN4,CRTAC1,NUP214,ST8SIA3,LMO1,SEZ6" Drug 4770_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.81E-11 2.86E-06 1.06E-07 1.16E-06 29 177 "DPF1,ADD3,TUBB4A,APC,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,CDK5R2,BTRC,TNS1,PIK3CD,DNAJC12,BEST1,KIAA0513,RIMS3,DNAJC6,KCND3,SRGAP3,TMCC2,TTLL7,EFNA3,RASGRP2" Drug ctd:D007649 Ketamine CTD 1.04E-10 3.37E-06 1.20E-07 1.32E-06 72 803 "MAP6,MAPT,TMEM74,MBP,RTKN,KCNIP2,NDRG2,RXRG,SORCS1,AGT,SCN4B,ASIC4,MOG,SFPQ,SLC1A2,SLC2A5,LRRC55,ARHGAP5,ASCL1,TAGLN3,BRINP2,ATP1A2,ATP1A3,NKX6-2,ADGRB2,GFAP,NCDN,SLCO1C1,ACSBG1,ZNF638,C1QC,KAZN,MMD2,NRGN,HAP1,GRIN1,GRM3,TF,USP2,MFSD2A,INA,HRH3,TPM4,PCSK2,ZMYND8,GPR37L1,CHRM1,PLEKHB1,ZBED5,TMEFF2,HPCA,GDAP1L1,MICAL1,FAT3,ACBD5,POU3F2,CRLS1,VCAN,PHACTR3,CMTM5,PRKCG,HES5,SYTL2,PHYHIP,PLPPR1,PYGM,RASGRF1,PAK5,CRTAC1,JMJD1C,TTLL7,SLC39A12" Drug ctd:C013418 bromfenacoum CTD 1.37E-10 4.45E-06 1.53E-07 1.68E-06 62 645 "ABAT,MAP6,ACLY,RTN3,SLC25A25,RTN1,FABP7,ERMN,AGT,MOG,SFPQ,SGIP1,ANK3,ANXA7,PKP4,SH3GL2,APBB1,APC,GAS7,ARFGAP2,SLC8A2,NAXD,SNCB,ATP1A3,ATP2B2,TNIK,CAB39,GAD2,ALDH1L1,GFAP,MLC1,KAZN,CAMSAP2,CNTN2,NUDT21,GRIA4,INA,TJP1,AIFM1,TNR,PADI2,LGI1,HNRNPK,HEPACAM,CCDC136,CNTN1,VCAN,CTNND1,CTNND2,FAM131B,DNAJC6,HP1BP3,ATG16L1,C12orf4,RAP1GAP,ABI1,RTN4,ZYG11B,RBM12,VWA5A,SLC4A10,EPB41L1" Drug CID000005657 NSC7524 Stitch 1.75E-10 5.70E-06 1.90E-07 2.08E-06 29 182 "ASIC1,ACHE,RYR1,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ASIC4,B3GAT1,ATP1A2,ATP1A3,PALLD,SCN3B,GAD2,NKX6-2,NODAL,CACNA1A,CACNA1E,NPPA,CACNB2,GRIK3,GRIK4,PDE1C,PDYN,ASIC3,CHRM1,CHRNB2,CACNG7" Drug ctd:D020245 p-Chloromercuribenzoic Acid CTD 3.27E-10 1.06E-05 3.43E-07 3.76E-06 77 909 "TTYH1,MAP6,ASIC1,TMEM74,CNTNAP3,SYT9,SLITRK1,ADCYAP1R1,LRRTM4,SEMA6A,SOX6,CDC42BPA,ANK1,USP28,PPFIA1,BCAN,CACHD1,SHTN1,SLC1A2,BCO1,LRRC55,PKNOX2,SMARCE1,TMEM108,PALLD,SOX1,SOX5,JPH4,SALL3,STARD10,NFASC,NCAM1,LMO3,COLGALT2,STOX1,SMOC1,GFRA1,AJAP1,GLS,CNTN2,WSCD1,GPM6B,CACNB2,DDR2,GRM3,GUCY1A2,KCNK10,PAX6,REPS2,PCDH8,HRH3,CCDC136,CELF5,PRRX1,FAT3,POU3F2,SNCAIP,FEZ1,NCAN,DOCK7,PLD5,CTNND2,HES5,ZBTB16,SPIRE1,ZNF385B,RGMA,MED24,OLFM3,RABGAP1L,CALN1,RET,RFX4,RGS7,SFXN5,LMO1,SEZ6" Drug ctd:C014024 "2,4,5,2',4',5'-hexachlorobiphenyl" CTD 4.25E-10 1.38E-05 4.31E-07 4.73E-06 127 1835 "MAP6,IL17D,FAM43B,MRVI1,ARID1A,CSMD3,DSCAML1,FCGR1A,CHST15,DRAXIN,SCN4B,FGF1,PLA2G6,FGF14,SEMA6A,C1QTNF4,ASIC4,HPCAL4,MOBP,FOXM1,CDC42BPA,ANK1,ITSN1,PPM1E,GAS7,SLC1A6,RUFY2,MSR1,LRRC55,SLC8A3,SHANK2,CADPS,ARFGAP1,ASPH,RCOR3,KBTBD12,B3GAT1,IGSF9B,ATM,NRG3,ATP2B2,KIF21B,NMNAT2,KIF1B,NASP,RCOR2,ADHFE1,AJAP1,NFIA,ARHGEF7,GLS,VAMP1,PCDH11X,NHLH1,POPDC3,PSRC1,CNTN2,PRUNE2,ACSL6,B4GALNT4,ZEB1,CAMK2A,CECR2,DDR2,PSD3,RFFL,GPR88,GRM3,OMG,OPCML,TIE1,TJP1,NEURL1,PCDH9,CDH8,HRH3,TPM3,TPM4,MAGI1,PDE1C,PRMT8,PDE4B,CHRM1,PLEKHB1,TUB,SLC22A6,ST8SIA5,SLC25A27,NECAB2,NSD2,FAT3,MFSD4A,ETNPPL,MICAL2,PLCH2,DOCK7,CALY,CTNND1,MAPK8,HES5,BRINP3,PSD,ANKS1B,PHYHIP,LRRTM3,DNAJC6,PLPPR1,PTPRD,KCND3,NTM,KCNMA1,NAV2,KCNQ2,DLG2,RAB5B,TMEM255A,SLC17A6,SUSD4,FAM13C,DTNA,RET,USH1C,RFX5,TTLL7,CACNG7,EFNA3,SLC4A10" Drug ctd:C035988 procymidone CTD 5.63E-10 1.83E-05 5.54E-07 6.08E-06 26 156 "MBP,LRRC7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,ASIC3,DLGAP3,CADM1,NRXN1,NRXN2,NCAN,MAGI2,DPP6,CACNG7" Drug 3087_UP Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.45E-10 2.09E-05 6.16E-07 6.75E-06 29 192 "MOBP,C1orf61,CDC42BPA,AQP4,DNAH17,PALLD,RAP1GAP2,ALDH1L1,NEUROD1,GNG4,GPM6B,PSD3,GRIA1,INA,NEURL1,KCNK10,PADI2,TNS1,PCDH9,PDE4B,MICAL2,EDRF1,DLG3,PID1,TMEM255A,NUP214,TTLL7,SSPN,ROM1" Drug CID000003816 NSC759587 Stitch 1.14E-09 3.70E-05 1.06E-06 1.16E-05 47 444 "ABAT,ACHE,ADAR,ADORA1,ADORA3,GAS7,SLC1A2,MSR1,SLC8A2,MT3,SNAP25,ATP2B2,SOX10,GAD2,BCL2L2,GFAP,GFRA1,SYT4,CACNB2,NRGN,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,OLR1,OMG,TNFRSF1B,PDYN,CHRM1,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PRDM2,KCNA1,PTPRZ1,DLG2,SLC17A6,EEF1A2,EPB41L1" Drug 4121_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-09 3.88E-05 1.08E-06 1.18E-05 29 197 "EMID1,SYNDIG1,DOCK10,GAS7,SLC2A5,PKNOX2,GPR153,ASPH,BRINP2,CCDC181,FYN,ATP2B2,NMNAT2,LMO3,GFAP,RND1,AJAP1,OPCML,CHI3L2,CHRNB2,CAMKV,FADS2,SDC3,NOS1AP,NTM,RAB3IL1,ATN1,RGS10,SSPN" Drug ctd:D008044 Linuron CTD 1.42E-09 4.62E-05 1.25E-06 1.37E-05 23 129 "LRRC7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,MAGI2,DPP6,CACNG7" Drug CID000005514 T2755 Stitch 1.83E-09 5.95E-05 1.57E-06 1.72E-05 17 71 "ABAT,ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,CA14,ASIC3,PTCH1" Drug CID000448294 AC1L9LT0 Stitch 3.03E-09 9.85E-05 2.53E-06 2.77E-05 22 123 "APC2,ANK1,ANK2,ANK3,APC,MAGI3,NKX6-2,BTRC,GRIA1,GRIA2,CRB1,TJP1,PCSK2,MAGI1,CADM1,TJP2,ARHGEF4,KCNA4,PARD6A,DLG2,DLG3,EPB41" Drug 413_UP trichostatin A; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 4.57E-09 1.48E-04 3.71E-06 4.07E-05 28 196 "ADD3,FHL1,PPM1E,SLC1A2,ZNF365,ALDH4A1,ATP1A2,FYN,TNIK,ZCCHC24,ZSWIM8,FXYD6,ACSBG1,GLS,BTRC,ATF7,CAMK2A,DDR2,GRIA4,GRIN1,TF,OPCML,DNAJC12,IFFO1,ARHGEF4,MAPK8,PTCH1,ABCC9" Drug 4239_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.13E-09 1.67E-04 4.06E-06 4.45E-05 28 197 "ACTN2,RYR1,LRRTM4,MSR1,SLCO1A2,CCDC181,TNIK,NFASC,RND1,ACSBG1,MLC1,SEMA4A,GNG4,NPPA,GRIA1,TNS1,ARHGAP22,SLC22A6,ZFYVE9,CNTN1,CHD5,MAPK8,RIMS3,ITIH2,KCNA2,SRGAP3,ATN1,VWA5A" Drug 3827_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "NDRG2,RYR1,FOXRED2,KIAA1109,AQP4,SLN,ATP2B2,VAMP1,CACNA1A,GPR17,HAP1,GPR88,USP2,PTGDR2,PDE2A,CHI3L2,CNTN1,BEST1,NECAB2,SPATA6,CTNND2,PTAFR,MAGI2,KCND3,RASGRF1,ABCC9,VWA5A,LRRC23" Drug 2550_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "MAPT,SYNDIG1,NDRG2,LRRTM4,ANK1,ANK3,PKP4,AQP4,MSR1,PKNOX2,ASPH,ACSBG1,GLS,WSCD1,TGFBR3,PTGDR2,SCRG1,CHRNB2,PHKG1,FLRT1,PMP2,PKN2,CTNND2,MAPK8,EDRF1,KCNMA1,SEC61A2,SSPN" Drug 3797_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.75E-09 1.87E-04 4.24E-06 4.65E-05 28 198 "ACTN2,ADORA3,AGT,C1orf61,AQP4,SLC1A6,PKNOX2,SLN,ATP2B2,CADM3,SOX10,ALDH1L1,CRB1,PADI2,TNS1,PTGDR2,CABP1,PROX1,PTAFR,PRDM2,MAGI2,SRGAP3,KCNJ4,ATN1,ABCC9,RET,LRRC23,RASGRP2" Drug ctd:C009618 "O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate" CTD 5.98E-09 1.94E-04 4.32E-06 4.73E-05 29 211 "ACHE,FGF14,SEMA6A,FOXG1,ANK3,NLGN1,CSPG5,ATP2B2,NFASC,NCAM1,NDUFA5,NKX2-2,SEMA4A,CNTN2,TF,INA,TNR,NLGN3,NRXN1,NRXN2,SEMA5B,CPT1C,RIMS4,NOS1AP,DPYSL5,TOMM20,RET,SH3GLB1,ELAVL3" Drug 3243_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.02E-09 2.28E-04 4.95E-06 5.43E-05 26 175 "ADD3,TUBB4A,SEMA6A,HPCAL4,PPM1E,SYBU,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,NAV2,EFNA3,VWA5A,RASGRP2" Drug DB00142 L-Glutamic Acid Drug Bank 7.20E-09 2.34E-04 4.98E-06 5.46E-05 16 68 "ABAT,FOLH1,SLC1A2,SLC1A6,SLC1A7,GAD2,GLS,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,SLC25A18" Drug ctd:C038939 enzacamene CTD 8.83E-09 2.87E-04 5.97E-06 6.55E-05 22 130 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug ctd:C069837 fullerene C60 CTD 1.88E-08 6.12E-04 1.25E-05 1.37E-04 104 1501 "SERPINA3,MAP6,ASIC1,ACHE,APC2,TMEM74,MBP,SLITRK1,ADORA1,FOXRED2,CHST15,HOGA1,PLA2G6,ASIC4,SOX6,RASA3,ITSN1,APBA2,GAS7,CACHD1,SYBU,ST3GAL3,SLC2A5,BCO1,YPEL4,SLC14A1,SCMH1,GPR153,DNAH17,SLN,B3GAT1,ALDH4A1,SNAP25,ZCCHC24,AHCYL1,LHFPL4,CPLX2,LMO3,GPR162,GJB1,ADHFE1,SEPT3,FAM168A,MLC1,ARHGEF7,C1QC,UNC5D,MMD2,WSCD1,CACNA1E,NPPA,B4GALNT4,NRGN,TMEM151B,NUCB1,AKNA,GRIN1,ATP13A2,OLR1,OPCML,USP2,MFSD2A,TIE1,ZFP91,PAX6,TNS1,DCLK1,PTGDR2,NTSR2,CHRM1,CHRM4,NLGN3,ZFYVE9,PIK3CD,UBTF,CCDC136,CELF5,IFFO1,TENM4,PRKACB,SDC3,CALY,ARHGEF4,NRSN1,HES5,PROX1,MASP1,ZBTB16,MED24,NTM,TMCC2,KCNN3,RAB3IL1,KLRC2,SLC17A6,ATG16L1,RASGRF1,CAMK1G,PHC2,TTLL7,EEF1A2,VANGL2,EFNA3,RASGRP2" Drug 3123_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.11E-08 6.86E-04 1.37E-05 1.51E-04 27 197 "CEND1,ASIC4,CDC42BPA,AQP4,GPR153,PALLD,WDTC1,CPLX2,ALDH1L1,CACNB2,OMG,TJP1,TNS1,PDE1C,CHRM4,ATRNL1,EDRF1,SYNC,PMEPA1,ITIH2,TMCC2,DLG3,RGS10,TTLL7,ELAVL4,RCAN2,LRRC23" Drug CID000104810 barium Stitch 2.17E-08 7.06E-04 1.38E-05 1.52E-04 23 148 "ADORA1,ANXA7,MTR,CACNA1A,CACNA1E,NPPA,P2RX7,KCNK10,CHRM1,PRKCG,PKN2,PRKCZ,KCNA1,KCNA6,KCNC1,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3" Drug CID000005123 willardine Stitch 2.21E-08 7.18E-04 1.38E-05 1.52E-04 11 32 "FOLH1,ADHFE1,ABCC8,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,KCNA2" Drug 5625_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.41E-08 7.81E-04 1.45E-05 1.59E-04 25 173 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,USP2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,JAKMIP2,EFNA3" Drug CID000003779 isoproterenol Stitch 2.42E-08 7.85E-04 1.45E-05 1.59E-04 58 669 "ASIC1,ADAR,ADARB2,ADCY2,RYR1,ADORA1,ADORA3,TUBB4A,AGT,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,BBOX1,ANK2,AQP4,PDE8B,NRG3,SCN3B,MYH7,GFAP,NEUROD1,ABCC8,GNAS,CACNA1A,NPPA,CACNB2,AZIN2,TF,GUCY1A2,P2RX7,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,HPSE2,CHGA,ASIC3,CHRM1,P2RY12,VCAN,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,KLK6,TUBB2B,KCND3,KCNK1,PCDH15,KCNMA1,PYGM,ABCC9,LPAR6" Drug 6671_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.55E-08 8.28E-04 1.51E-05 1.65E-04 26 186 "ABAT,CEND1,SORBS1,TAGLN3,FYN,TNIK,ADGRB2,RGL1,RND1,GLS,CDK5R2,HAP1,USP2,TNS1,LILRA4,DNAJC12,VCAN,KIAA0513,DNAJC6,JAKMIP2,PLPPR4,SRGAP3,PID1,DSCAM,EFNA3,VWA5A" Drug ctd:D004390 Chlorpyrifos CTD 2.65E-08 8.59E-04 1.53E-05 1.68E-04 75 968 "MAG,ASIC1,ACHE,SYT9,SLITRK1,TESK2,AGT,FGF1,MOBP,MOG,CDC42BPA,SLC1A2,SLC1A6,SLC1A7,CGREF1,SCG3,SLIT1,ATM,DKK3,USP33,NCAM1,ERBIN,GFAP,FGF17,ADHFE1,NEUROD1,RND1,CNTN2,ZEB1,CAMK2A,SYT6,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,USP2,TJP1,ZFP91,CD81,TNR,RBFOX2,PCSK2,PDE1C,PDE3B,PDYN,HMGB1,CHGA,PFKFB3,CHRM1,CHRM4,CHRNB2,HNRNPK,NEGR1,POU3F2,MED1,CHD5,PRKAB2,DZIP3,MAPK8,ZBTB16,RIMS3,CSDE1,DLG2,PYGM,RTN4,L1CAM,RET,ST8SIA3,VANGL2,ELAVL4,BAALC" Drug 4837_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.92E-08 9.49E-04 1.66E-05 1.83E-04 27 200 "ADORA3,C1orf61,APC,AQP4,TAGLN3,IGSF9B,SNAP25,SCN3B,NCAM1,ACSBG1,WSCD1,HAP1,PSD3,OPCML,HRH3,ADGRG1,CAMKV,CABP1,IFFO1,OSBPL3,NCAN,ITIH2,ATN1,DSCAM,USH1C,LRRC23,RASGRP2" Drug 5441_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.41E-08 1.11E-03 1.91E-05 2.10E-04 25 176 "DPF1,ADD3,TUBB4A,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,RGL1,ACSBG1,GLS,CDK5R2,USP2,SERPINE2,PIK3CD,DNAJC12,MAPK10,KIAA0513,DNAJC6,JAKMIP2,TMCC2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug ctd:C118580 octylmethoxycinnamate CTD 3.57E-08 1.16E-03 1.96E-05 2.15E-04 22 140 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug CID000166931 phosphine oxide Stitch 4.05E-08 1.32E-03 2.19E-05 2.40E-04 19 107 "MAG,MBP,RYR1,MOBP,MOG,KIF1B,GJB1,MLC1,OMG,PC,PRKACB,PRKCG,PKN2,PRKCZ,KCNC1,KCNJ10,KCNMA1,KCNQ2,ROM1" Drug CID006437089 PbTx-1 Stitch 4.28E-08 1.39E-03 2.26E-05 2.48E-04 10 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,GABBR1,SCN3B,GJB1,ASIC3,KCNA2" Drug CID000003538 GYKI 52466 Stitch 4.43E-08 1.44E-03 2.26E-05 2.48E-04 14 58 "SLC1A2,BCO1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,MAPK10,PTCH1,ABCC9,NUP214" Drug ctd:D006220 Haloperidol CTD 4.45E-08 1.45E-03 2.26E-05 2.48E-04 37 344 "DPF1,MAG,SERPINA3,MBP,RXRG,HPCAL4,MOG,SLC1A2,SNAP25,ATP1A3,FYN,TNIK,GAD2,VAMP1,SYT4,GNAS,CACNA1A,NPPA,CAMK2A,GRIA1,GRIA2,GRIK2,GRIK4,GRIN1,TF,CDC42,DCLK1,CHRM4,NCAN,PRKACB,PRKCZ,MAPK8,WBP1L,KCNA1,SLC17A6,RASGRF1,RTN4" Drug CID000000681 dopamine Stitch 4.45E-08 1.45E-03 2.26E-05 2.48E-04 60 715 "ABAT,ACHE,CLIP1,ADCY2,RYR1,ADORA1,ADORA3,AGT,FGF14,ACTL6B,FOXM1,SLC1A2,SNAP25,SNCB,ATP1A3,FYN,SOX10,GAD2,ARPP21,NPAS3,NDUFA5,GFAP,GFRA1,ADHFE1,GNAS,CACNA1A,CACNA1E,NPPA,PRLHR,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRIN1,GRM3,CCKBR,GUCY1A2,PAH,HRH3,PDE3B,PDYN,NTSR2,CHRM1,CHRNB2,PTPA,CALY,PRKCG,PKN2,PRKCZ,KCNA6,KCNJ4,KCNJ9,KCNJ10,SLC17A6,SLC6A15,RET,RGS10,EEF1A2,EN2" Drug CID000003150 AC1L1FA8 Stitch 5.15E-08 1.67E-03 2.57E-05 2.82E-04 13 50 "ADCY2,SLC1A2,SOX10,GFAP,NUCB1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3" Drug CID000001065 quindine Stitch 5.34E-08 1.73E-03 2.63E-05 2.88E-04 28 219 "ASIC1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SHANK2,SLC14A1,SLCO1A2,SCN3B,CACNB2,KCNK10,ASIC3,CHRM1,CHRNB2,SULT4A1,DPYSL5,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNK1,KCNK2,KCNMA1,KCNN3" Drug 4098_UP Furazolidone [67-45-8]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.78E-08 2.20E-03 3.29E-05 3.60E-04 26 195 "MAPT,AGT,BBOX1,APC,NTNG1,GAS7,RPH3A,PKNOX2,ASCL1,ATP1A2,FGF17,KLHL4,GRIN1,TF,SPX,GUCY1A2,CDH10,HPCA,CADM1,ST8SIA5,CTNND2,NOS1AP,PHYHIP,KCNJ10,FAM13C,RASGRP2" Drug CID000003763 isoflurane Stitch 8.22E-08 2.67E-03 3.93E-05 4.31E-04 32 279 "MAG,ASIC1,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,ATP2B2,SCN3B,VAMP1,NODAL,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,LEFTY2,KCNK10,TPM3,ASIC3,CHRM1,CHRNB2,NSD2,PRKCG,KCNA1,KCNK2,KCNMA1,ABCC9" Drug 4421_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.35E-08 2.71E-03 3.93E-05 4.31E-04 26 197 "DPF1,MAG,ASIC1,NDRG2,KIAA1109,FHL1,RASA3,GAS7,SLC14A1,ATP2B2,ADAM15,ALDH1L1,GNAS,GNG3,ATF7,GRIN1,TPM3,PDE3B,ASIC3,PACSIN1,SNCAIP,RGS6,MAPK8,PARP11,VWA5A,RASGRP2" Drug 1529_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.25E-08 3.01E-03 4.29E-05 4.71E-04 26 198 "RYR1,ADORA1,KIAA1109,ITSN1,BCAN,SYBU,GPR153,ATM,ATP1A3,INKA2,GLS,GPM6A,NPPA,CDH8,PCSK2,PDE1C,GPR37L1,FADS2,PACSIN1,MED1,SNCAIP,SYNC,MAGI2,RAD52,ATN1,VWA5A" Drug CID000000923 sodium Stitch 9.45E-08 3.07E-03 4.33E-05 4.74E-04 72 944 "ASIC1,ADAR,F3,ADCY2,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,ASRGL1,ANK2,ANK3,SLC1A2,SLC7A14,SLC1A6,SLC1A7,SLC2A5,SLC6A9,SLC8A2,SLC8A3,SLCO1A2,MTR,ATP1A2,ATP1A3,ATP2B2,SCN3B,NKX6-2,GART,DNER,GLS,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,INA,P2RX7,TJP1,TPM3,ASIC3,CHRNB2,SLC22A6,CP,KCNT2,PRKACB,PRKCG,PKN2,PRKCZ,BLOC1S6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,DLG3,SLC17A6,SLC6A15,UEVLD" Drug 5906_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "KCNIP2,ADCY2,FGR,SLC1A7,TNIK,ZCCHC24,CADM3,NMNAT2,CPLX2,COLGALT2,PHLDB1,RND1,AJAP1,HAP1,TMEM151B,OPCML,CCKBR,KCNK10,TMPRSS5,PIK3CD,SULT4A1,CNTN1,RIMS3,KCNJ4,ELAVL3,RASGRP2" Drug 3614_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "APC2,GRAMD1B,PLA2G6,FHL1,AMPH,RASA3,SLC6A9,SHANK2,ATP1A2,ATP2B2,NMNAT2,ALDH1L1,PHLDB1,POPDC3,ROBO3,CACNA1A,USP2,PKN2,RIMS3,PTAFR,SV2A,SRGAP3,RAB3IL1,DNAH9,RAD52,NUP214" Drug 3546_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-07 3.33E-03 4.50E-05 4.93E-04 26 199 "ADCY2,RYR1,SEMA6A,FOXG1,RPH3A,BCO1,MSR1,PKNOX2,GPR153,SORCS3,ATP1A3,WDTC1,ZSWIM8,AJAP1,GNG3,WSCD1,GPM6A,GPM6B,ATF7,TCF7L2,OLR1,PLCH2,MAGI2,KCND3,TMEM255A,RASGRP2" Drug 2728_UP Butacaine [149-16-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ABAT,MAPT,TUBB4A,PLA2G6,AMPH,APBA2,SLC1A7,ASCL1,TAGLN3,ATP1A3,PALLD,CADM3,GAD2,ROBO3,GRIK2,USP2,PDE1C,HPSE2,ZFYVE9,CAMKV,FLRT1,VAV2,POU3F2,KCNC1,FAM13C,RASGRP2" Drug 6405_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ARID1A,NDRG2,HPCAL4,APBA2,APC,BCAS1,SLC1A7,BCO1,CGREF1,ATP1A3,GAD2,INKA2,PHLDB1,GLS,WSCD1,NPPA,ZEB1,USP2,ASIC3,ZFYVE9,SULT4A1,SPATA6,VCAN,SDC3,MAPK8,USH1C" Drug 6181_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-07 3.68E-03 4.78E-05 5.25E-04 26 200 "ACTN2,TUBB4A,FHL1,BCAS1,MSR1,SHANK2,GPR153,TAGLN3,ASTN1,PALLD,MYBPC1,CADM3,ADGRL3,GRIK2,CRB1,GUCY1A2,CELF3,PTGDR2,HPCA,NCAN,PROX1,PRDM2,SMG7,SV2A,KCNK1,EFNA3" Drug CID000003019 diazoxide Stitch 1.15E-07 3.74E-03 4.80E-05 5.26E-04 28 227 "TUBB4A,FOXM1,GART,ABCC8,NPPA,GRIA1,GRIA2,GRIA4,GRM3,KCNK10,KCNT2,PRKCG,TUBB2B,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNMA1,KCNN3,KCNQ2,ABCC9" Drug CID000002910 cyclothiazide Stitch 1.18E-07 3.84E-03 4.86E-05 5.33E-04 18 103 "MBP,SLC1A2,SLC1A6,SLC8A2,GFAP,CACNA1A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,SLC22A6,NCAN,PTPRZ1,KCNMA1" Drug 2268_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.26E-07 4.08E-03 5.11E-05 5.60E-04 24 175 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,ZNF365,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,WSCD1,USP2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3,RASGRP2" Drug CID000038945 tocainide Stitch 1.37E-07 4.44E-03 5.48E-05 6.01E-04 10 30 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ANK2,SCN3B,ACOT7,ASIC3,KCNA4" Drug ctd:C010902 decabromobiphenyl ether CTD 1.39E-07 4.53E-03 5.52E-05 6.06E-04 105 1582 "RIMKLA,MAPT,ACHE,DUSP27,RYR1,HHATL,TOMM40L,SCN3A,SCN4B,PLA2G6,FGF14,BBOX1,CDC42BPA,ANK1,USP28,ITSN1,GPAM,CACHD1,ST8SIA1,AQP4,SLC6A9,ASCL1,ASTN1,RCOR3,SNAP25,TMEM151A,SNCB,GABBR1,ZCCHC24,ILDR2,MYH7,ARPP21,TTLL9,STARD10,NFASC,BCL2L2,RCOR2,SLCO1C1,FAM168A,MLC1,ZNF638,DCLK2,GNG3,CDK5R2,TMEM136,TBX15,GPM6B,DDR1,CACNB2,CAMK2A,GRIK3,CCKBR,SPX,USP2,GUCY1A2,PAH,CDK11B,PAX6,TNR,PCDH8,DCLK1,RBFOX2,TPM4,PDE1A,PDYN,TUB,CHRNB2,NLGN3,DLGAP3,ANLN,UBTF,CPT1C,A2ML1,ST8SIA5,FAM181B,PRRX1,PNKD,VCAN,RBPJ,PRKAB2,PRKACB,DZIP3,SDC3,PKN2,MAPK8,SPIRE1,PTCH1,KCNA4,PLPPR4,KCND3,KCNJ10,ARNT2,KCNMA1,NAV2,KCNN3,DLG2,PYGM,PLEKHB2,RET,RFX4,RFX5,VANGL2,OLIG2,PRRT4,RCAN2" Drug CID000003878 lamotrigine Stitch 1.54E-07 5.01E-03 5.97E-05 6.55E-04 19 116 "ABAT,ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,PTPN5,ASIC3,PTCH1,CACNG7" Drug ctd:D003024 Clozapine CTD 1.56E-07 5.06E-03 5.97E-05 6.55E-04 39 392 "DPF1,SERPINA3,MBP,RXRG,AGT,HPCAL4,MOBP,SLC1A2,SNAP25,GABBR1,TNIK,GAD2,CPLX2,GFAP,VAMP1,SYT4,GNAS,CACNA1A,CAMK2A,GRIA1,GRIA2,GRIK2,GRIN1,CCKBR,DCLK1,PDE4B,CHGA,CHRM1,SERPINE2,NCAN,PRKACB,PRKCZ,WBP1L,KCNA1,KCNK2,SLC17A6,RASGRF1,RTN4,RGS7" Drug 4821_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.56E-07 5.07E-03 5.97E-05 6.55E-04 24 177 "ADD3,TUBB4A,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,CDK5R2,TGFBR3,USP2,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,VWA5A,RASGRP2" Drug 6454_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.74E-07 5.65E-03 6.49E-05 7.12E-04 24 178 "DPF1,ADD3,TUBB4A,C1orf61,PPM1E,SORBS1,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,POPDC3,CDK5R2,WSCD1,TNS1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 4388_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.74E-07 5.65E-03 6.49E-05 7.12E-04 24 178 "DPF1,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,NMNAT2,RGL1,RND1,ACSBG1,GLS,CDK5R2,TGFBR3,PIK3CD,DNAJC12,KIAA0513,PTAFR,DNAJC6,TMCC2,EFNA3,VWA5A,RASGRP2" Drug CID000002520 verapamil Stitch 1.82E-07 5.92E-03 6.73E-05 7.38E-04 45 490 "ASIC1,ADCY2,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SLCO1A2,ATP1A2,ATP1A3,ATP2B2,SCN3B,MYH7,NODAL,CACNA1A,CACNA1E,NPPA,CACNB2,LEFTY2,KCNK10,HPSE2,ASIC3,CHRM1,CHRNB2,KCNT2,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNMA1,KCNN3,KCNQ2,ABCC9,CACNG7" Drug 2523_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.12E-07 6.90E-03 7.75E-05 8.50E-04 25 193 "EMID1,NDRG2,KIAA1109,CDC42BPA,PPM1E,ALDH4A1,CCDC181,FXYD6,NCAM1,RGL1,GNG4,PCDH9,PTGDR2,PHKG1,ZFYVE9,KIAA1549L,NMT2,CCSER2,FEZ1,DZIP3,RIMS3,DNAJC6,USH1C,EFNA3,VWA5A" Drug 4349_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.39E-07 7.75E-03 8.58E-05 9.40E-04 24 181 "ADD3,TUBB4A,HPCAL4,PPM1E,ZNF365,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,USP2,TNS1,PDE1C,SERPINE2,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,ST8SIA3,TTLL7,VWA5A,RASGRP2" Drug ctd:D010622 Phencyclidine CTD 2.43E-07 7.88E-03 8.58E-05 9.40E-04 16 86 "MBP,MOBP,GABBR1,GAD2,CPLX2,GFAP,GNAS,CAMK2A,GRIA4,GRIN1,CCKBR,PRKCG,KCNH1,KCNJ4,SLC17A6,RTN4" Drug ctd:D000431 Ethanol CTD 2.43E-07 7.89E-03 8.58E-05 9.40E-04 106 1620 "ABAT,ACHE,ACLY,MBP,SYT9,F3,ADCY2,RXRG,ADCYAP1R1,FABP7,ADORA1,TUBB4A,AGT,FGF1,AMPH,NTNG1,GPAM,BCAS1,AQP4,SLC1A2,SLC1A6,RPH3A,SLC6A9,ARHGAP5,SLC8A3,MT3,SCG3,MTR,ADGRA1,SNAP25,ATM,FYN,ATP2B2,MYT1L,ILDR2,ARPP21,ALDH1L1,NDUFA5,GFAP,GFRA1,PHLDB1,VAMP1,GNG3,MMD2,NPPA,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,ADAMTS8,GPR88,GRM3,TF,OPCML,TJP1,AIFM1,CDK11B,CDC42,PDE3B,PDE4B,PDYN,HMGB1,HNRNPK,HPCA,SERPINE2,CADM1,OPALIN,FADS2,DNAJC12,CCDC136,PMS2,PPP3CB,PRKACB,FMN2,CMTM5,PRKCG,PRKCZ,IGSF1,MAPK8,ZBTB16,DPYSL5,TUBB2B,PTCH1,PTHLH,KCNA1,PTPRO,NTM,AK5,KCNMA1,NKAIN1,DNM2,SLC17A6,SLC25A18,ATN1,DTNA,L1CAM,RET,ST8SIA3,PLEKHO1,RASGRP2" Drug 7237_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-07 8.42E-03 9.06E-05 9.93E-04 25 195 "ADORA1,KIAA1109,PLA2G6,ANK1,GAS7,CCDC88A,ATM,AJAP1,VAMP1,POPDC3,BTRC,PSD3,OMG,USP2,NEURL1,CHD5,SDC3,ARHGEF4,PROX1,KCNC1,KCND3,KIF2A,RASGRF1,SSPN,EFNA3" Drug CID000003446 gabapentin Stitch 2.64E-07 8.56E-03 9.11E-05 9.99E-04 23 169 "ABAT,ASIC1,RYR1,ADORA1,SCN3A,SCN4B,SCNN1D,ASIC4,FOXG1,SCN3B,CACNA1A,CACNA1E,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,ASIC3,ETNPPL,CACNG7" Drug ctd:D003561 Cytarabine CTD 2.84E-07 9.22E-03 9.68E-05 1.06E-03 51 598 "TTYH1,NDRG2,RTN1,FABP7,DISP3,BCAR3,SGIP1,CNIH2,NTNG1,SLITRK3,SLN,FYN,PHYHIPL,RGL1,GLS,ROBO3,PSRC1,GPM6A,GPR19,TCF12,DDR2,PSD3,GRIA2,OLR1,CCKBR,TGFBR3,INA,GUCY1A1,CELF3,PAX6,MAGI1,PDE1A,PDE4B,JAM2,SEMA5B,PRKCZ,HES5,KLK6,SYTL2,STMN4,PARD6A,PTPRZ1,SRGAP3,NTM,NAV2,CAB39L,RAB5B,SLC17A6,ATN1,ATL1,BSCL2" Drug 2681_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.86E-07 9.30E-03 9.68E-05 1.06E-03 25 196 "ACTN2,MDM4,RTN1,ADCY2,HPCAL4,MOBP,FOXG1,SLC8A2,TAGLN3,ATP2B2,MYRF,GRIK2,GRIN1,OMG,CDH10,GPR37L1,HPSE2,CHI3L2,PHKG1,CCSER2,ATN1,CAMK1G,USH1C,EFNA3,LPAR6" Drug CID006324635 LY339434 Stitch 2.94E-07 9.56E-03 9.75E-05 1.07E-03 6 9 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4" Drug CID005311255 Ly294486 Stitch 2.94E-07 9.56E-03 9.75E-05 1.07E-03 6 9 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 7037_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.16E-07 1.03E-02 1.02E-04 1.12E-03 25 197 "MAPT,NDRG2,FOXG1,CDC42BPA,ITSN1,BCAS1,SHANK2,SPART,ARHGEF7,GNG4,TCF7L2,NUMA1,CDH10,UBTF,DZIP3,CTNND1,EDRF1,RIMS3,PRDM2,PARD6A,NKAIN1,RAD52,DTNA,EFNA3,RBM12" Drug 2401_UP Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.16E-07 1.03E-02 1.02E-04 1.12E-03 25 197 "MDM4,ADORA1,TUBB4A,DOCK10,BCAS1,AQP4,GPR153,ASPH,ALDH4A1,ATP2B2,AJAP1,TCF7L2,NUMA1,PSD3,OLR1,TPM3,COL9A2,PRKCZ,MAPK8,KLK6,ITIH2,PTPRD,KCND3,ATN1,DSCAM" Drug ctd:C038091 butylparaben CTD 3.19E-07 1.04E-02 1.02E-04 1.12E-03 22 158 "ABAT,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,GLS,CACNA1A,CACNA1E,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIK4,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2,DPP6" Drug CID000001207 MK-801 Stitch 3.20E-07 1.04E-02 1.02E-04 1.12E-03 32 296 "ACHE,ADORA1,ADORA3,FOXM1,FOLH1,SLC1A2,B3GAT1,SOX10,GAD2,NPAS3,NCAM1,GFAP,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,PDE2A,PDE4B,PDYN,NTSR2,CHRM1,CHRNB2,PRKCG,CTNND2,PTCH1,EEF1A2,OLIG2" Drug 7535_DN irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.27E-07 1.06E-02 1.03E-04 1.13E-03 23 171 "MBP,LGR4,GRAMD1B,CHST15,BCAR3,ITSN1,TACC2,CAB39,ERBIN,ARHGEF7,CAMSAP2,WWC1,TCF7L2,ZEB1,TCF12,PDE1C,CCSER2,TENM4,OSBPL3,PKN2,PUM1,NAV2,ZNF248" Drug 3781_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "MDM4,KCNIP2,NDRG2,FABP7,AMPH,RASA3,GAS7,PDE8B,ATP1A2,NFASC,PHLDB1,VAMP1,SEMA4A,NPPA,GPR17,GRIA4,GRIN1,PDE4B,CHI3L2,PIK3CD,VAV2,PMP2,PRDM2,RAB3IL1,ATN1" Drug 4375_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "EMID1,AGT,FOXG1,CCDC88A,TAGLN3,ASPH,MYBPC1,KIF21B,SPART,NCAM1,AJAP1,FAM168A,GPM6B,OPCML,GUCY1A2,HRH3,CHI3L2,PIK3CD,CNTN1,POU3F4,PTHLH,STMN4,RAD52,ATN1,DTNA" Drug 4351_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "DPF1,MAPT,APC2,MBP,SLC14A1,SLCO1A2,TAGLN3,SCN3B,MLC1,CCKBR,SEZ6L,CHI3L2,PIK3CD,SULT4A1,CNTN1,MICAL2,NOS1AP,MASP1,PHYHIP,PTHLH,KCNMA1,PEX5,RGS7,LMO1,EN2" Drug 3568_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "C1orf61,APBA2,ALDH4A1,CCDC181,FYN,GAD2,LMO3,FGF17,PHLDB1,RND1,SLCO1C1,CAMK2G,GRM3,KCNK10,CDH8,PTGDR2,HPCA,SNCAIP,RIMS3,SLC17A6,PARP11,ATN1,NUP214,USH1C,EFNA3" Drug 4525_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "EMID1,RTN1,FOXRED2,AGT,FGF1,RASA3,PKNOX2,ADGRB2,NEUROD1,VAMP1,KAZN,ADGRL3,PRUNE2,SPX,TLL2,SEZ6L,PDE3B,IFFO1,RGS6,VCAN,KCNMA1,ATN1,RASGRF1,FAM13C,NUP214" Drug 4428_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.48E-07 1.13E-02 1.04E-04 1.14E-03 25 198 "ACTN2,NDRG2,FABP7,PDE8B,ATP2B2,SOX10,RND1,CDK5R2,KLHL4,CACNA1A,CAMK2A,GRIK2,ADAMTS8,NEURL1,ZMYND8,HPSE2,CHRNB2,VAV2,CTNND2,MAPK8,EDRF1,SUSD4,RASGRF1,RGS10,RASGRP2" Drug 5935_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.60E-07 1.17E-02 1.06E-04 1.16E-03 24 185 "ADD3,TUBB4A,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,CACNB2,ZEB1,PCDH9,PIK3CD,DNAJC12,SRGAP3,TMCC2,TTLL7,EFNA3,VWA5A" Drug CID000000806 "D-myo-inositol-1,4,5-triphosphate" Stitch 3.65E-07 1.19E-02 1.07E-04 1.17E-03 49 569 "MRVI1,ADCY2,RYR1,ADORA1,ADORA3,AGT,FGF1,ACTL6B,FOXM1,ANK2,ANK3,RASA3,ANXA7,DGKZ,DGKD,SLC8A3,B3GAT1,ATP1A2,ATP1A3,FYN,ATP2B2,AHCYL1,NEUROD1,CACNA1A,CACNA1E,NPPA,CACNB2,HAP1,GRM3,CCKBR,HRH3,ACOT7,CHGA,CHRM1,CABP1,PPP3CB,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PLPPR5,PTAFR,KCNMA1,PYGM,CACNG7,EN2,EPB41L1" Drug CID000003025 dibucaine Stitch 3.72E-07 1.21E-02 1.07E-04 1.18E-03 14 68 "ASIC1,ACHE,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,TF,ASIC3,CP,PLPPR5,CALN1,SLC25A18,PHC2" Drug 5081_UP Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "KCNIP2,NDRG2,MOBP,BCAN,AQP4,ATP1A3,ATP2B2,NEUROD1,VAMP1,KAZN,GNG4,OPCML,SEZ6L,PDE4B,GPR37L1,RGS6,VCAN,MAPK10,KCND3,ATN1,RASGRF1,FAM13C,DTNA,CAMK1G,ST8SIA3" Drug 3609_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "RYR1,KIAA1109,SLC30A10,GAS7,TAGLN3,DDX25,GAD2,NPAS3,COLGALT2,GFAP,ACSBG1,ROBO3,WSCD1,OPCML,PACSIN1,POU3F4,ETNPPL,RIMS3,ELMO1,PARD6A,SRGAP3,RAD52,CRTAC1,VWA5A,EN2" Drug 7226_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "APBA2,AQP4,SLN,ASTN1,ATP1A2,CADM3,ALDH1L1,MLC1,GNAS,GNG3,PRUNE2,WSCD1,PAH,DAAM2,TNS1,PTGDR2,PHKG1,ZFYVE9,SDC3,ARHGEF4,BEND5,SSPN,EFNA3,LMO1,RASGRP2" Drug 3260_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-07 1.25E-02 1.07E-04 1.18E-03 25 199 "ARID1A,FOXRED2,PLA2G6,SEMA6A,CDC42BPA,ANK3,ATP1A2,CPLX2,INKA2,RND1,VAMP1,POPDC3,NPPA,ZEB1,NUMA1,NEURL1,PDE3B,CHRNB2,SULT4A1,RIMS3,PTAFR,RAB3IL1,DTNA,VWA5A,ELAVL3" Drug CID000449524 IN-1 Stitch 3.90E-07 1.27E-02 1.08E-04 1.19E-03 11 41 "MAG,MBP,RTN3,RTN1,FGF1,MOBP,MOG,OMG,TNR,RTN4,EN2" Drug 3131_UP Scopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.22E-07 1.37E-02 1.16E-04 1.27E-03 25 200 "PLA2G6,HPCAL4,FOXG1,AMPH,ANK3,AQP4,GPR153,ALDH1L1,ACSBG1,WWC1,PRUNE2,PSD3,GRIK2,GRIN1,OMG,TJP1,DAAM2,CAMKV,SULT4A1,CTNND2,KCND3,TTLL7,SIDT2,ELAVL3,ROM1" Drug ctd:D007657 Ketone Bodies CTD 4.36E-07 1.42E-02 1.19E-04 1.31E-03 46 522 "MBP,CEND1,ARID1A,PLEKHG5,ADCY2,RXRG,GRAMD1B,FGF14,ANK3,PKP4,DGKZ,GPAM,BCAN,SCG3,ATP1A2,TNIK,ARPP21,TTC9B,CPLX2,NASP,CLASP2,GFRA1,ZNF638,NRGN,CAMK2A,SYT6,GRIA2,GRIK4,PTPN5,P2RX7,PADI2,PCSK2,ACOT7,CADM1,MEAF6,CELF5,CRMP1,CALY,PLPP4,NOS1AP,PSD,TOMM20,KCNJ9,SLC17A6,RTN4,RGS7" Drug 5572_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.48E-07 1.45E-02 1.21E-04 1.33E-03 23 174 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,USP2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3,VWA5A" Drug 2835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.96E-07 1.61E-02 1.32E-04 1.45E-03 23 175 "DPF1,ADD3,TUBB4A,PPM1E,SYBU,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,TGFBR3,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug 5417_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.96E-07 1.61E-02 1.32E-04 1.45E-03 23 175 "ADD3,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,ZEB1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,TMCC2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug CID000002474 bupivacaine Stitch 5.13E-07 1.67E-02 1.35E-04 1.48E-03 19 125 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,AQP4,SCN3B,MYBPC1,KCNK10,ASIC3,UBTF,HPR,PRKCG,PKN2,PRKCZ,KCND3,KCNK1,KCNK2,KCNQ2" Drug CID009543520 triphosphoinositide Stitch 5.24E-07 1.70E-02 1.37E-04 1.51E-03 30 273 "ASIC1,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,ANK1,DGKZ,DGKD,ARFGAP1,SCN3B,CDC42,ASIC3,CHRM1,PIK3CD,SDC3,PRKCG,PKN2,PRKCZ,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ9,KCNJ10,KCNK2,KCNQ2,EPB41,EPB41L1,EPB41L2" Drug CID006918393 YM928 Stitch 5.70E-07 1.85E-02 1.48E-04 1.62E-03 5 6 "GRIA1,GRIA2,GRIA4,GRM3,PTCH1" Drug CID000002351 bepridil Stitch 5.81E-07 1.89E-02 1.50E-04 1.64E-03 19 126 "ASIC1,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC8A2,SLC8A3,SHANK2,ATP2B2,SCN3B,CACNA1A,CACNA1E,CACNB2,ASIC3,CHRM1,KCND3,CALN1,CACNG7" Drug 1835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.90E-07 1.92E-02 1.51E-04 1.65E-03 24 190 "EPS8,EYA1,WLS,NDRG2,ADD3,TESK2,ITSN1,CAPRIN2,ALDH4A1,PALLD,NCAM1,RGL1,CAMSAP2,GPR19,NRGN,ATP13A2,PADI2,DNAJC12,FEZ1,RIMS3,PTCH1,DNAJC6,EFNA3,EPB41L2" Drug 3993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.09E-07 1.98E-02 1.53E-04 1.68E-03 23 177 "ABAT,TESK2,SORBS1,TAGLN3,BRINP2,FYN,TNIK,ZCCHC24,RGL1,RND1,GLS,VAMP1,TNS1,PCDH9,DNAJC12,FEZ1,KIAA0513,PTCH1,DNAJC6,PLPPR4,SRGAP3,EFNA3,RASGRP2" Drug 4768_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.09E-07 1.98E-02 1.53E-04 1.68E-03 23 177 "DPF1,ADD3,TUBB4A,FHL1,HPCAL4,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,TNS1,SERPINE2,PIK3CD,DNAJC12,DZIP3,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug CID000003689 ifenprodil Stitch 6.50E-07 2.11E-02 1.62E-04 1.78E-03 14 71 "ADGRV1,ADORA1,AQP4,FYN,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,PDYN,RASGRF1" Drug CID000005114 3-(1H-pyrrole-2-carboxylate Stitch 6.80E-07 2.21E-02 1.69E-04 1.85E-03 27 233 "MAG,RYR1,ANK2,SLC8A2,SNAP25,ATP2B2,MYBPC1,WDTC1,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,GUCY1A2,CHRM1,CAMKV,CABP1,PRKACB,PRKCG,KCND3,KCNMA1,KCNN3,CAMK1G,NUP214" Drug ctd:D015655 1-Methyl-4-phenylpyridinium CTD 7.56E-07 2.46E-02 1.86E-04 2.04E-03 106 1659 "EPS8,RPL38,MAPT,ACHE,MEG3,WLS,SLITRK1,RYR1,ADORA1,TUBB4A,AGT,SCN3A,SFPQ,APC,SORBS1,AQP4,SFMBT2,SLC6A9,NAXD,SMARCE1,SNCB,ATP2B2,DKK3,B3GALT2,ARPP21,SALL3,STARD10,GART,ADGRB2,DNER,NASP,NFASC,LMO3,COLGALT2,BCL2L2,GFAP,FGF17,RND1,ABCC8,PCDH11X,NHLH1,ROBO3,UNC5D,KLHL4,WSCD1,TCF7L2,GPR19,DIRAS1,NRGN,NUDT21,DDR2,SYT6,VSTM2A,AKNA,GRIA2,RFFL,ATP13A2,AIFM1,KCNK10,TNFRSF1B,CDC42,IGSF21,PADI2,TNS1,PCDH9,CDH10,DCLK1,RBFOX2,MAGI1,CHGA,ZBED5,TMEFF2,SLC22A6,GDAP1L1,NEGR1,FAM181B,SLC25A27,COL9A2,CP,POU3F2,KCNT2,VCAN,CTNND1,MAPK8,MAPK10,PSD,RIMS3,PHYHIP,SIRPA,PLPPR1,JAKMIP2,SHD,MAGI2,PTPRO,KCNJ4,KCNJ11,RAB5B,FAM13C,RTN4,SLC6A15,RET,EEF1A2,ELAVL3,ELAVL4,EN2,SEZ6" Drug CID000001299 AC1L1B62 Stitch 7.76E-07 2.52E-02 1.90E-04 2.08E-03 8 21 "F3,FOLH1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 2247_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-07 2.67E-02 1.98E-04 2.17E-03 23 180 "DPF1,ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,PTAFR,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 2639_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.22E-07 2.67E-02 1.98E-04 2.17E-03 23 180 "ARID1A,ADD3,TUBB4A,PPM1E,ZNF365,ALDH4A1,FYN,ZCCHC24,NPAS3,ALDH1L1,RGL1,RND1,ACSBG1,GLS,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,KCNA1,TMCC2,GNE" Drug CID000161645 oriens Stitch 8.36E-07 2.72E-02 2.00E-04 2.19E-03 21 154 "ACHE,ADORA1,BCAN,SLC8A2,SNAP25,GAD2,GFAP,GRIA1,GRIA2,GRIA4,GRIK4,GRM3,CHRM1,NCAN,PRKCG,KCNA6,KCNC1,PTPRZ1,KCNJ9,NUP214,RGS7" Drug CID000001221 "R,S)-AMPA" Stitch 9.30E-07 3.02E-02 2.21E-04 2.42E-03 10 36 "AMPH,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TUB,NTM" Drug 3812_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.49E-07 3.08E-02 2.22E-04 2.43E-03 24 195 "DPF1,CEND1,NLGN4X,APC,SLITRK3,SLC1A6,SLC2A5,PKNOX2,SLCO1A2,ATP1A2,ATP2B2,SLCO1C1,GRM3,GUCY1A2,PDE2A,CA14,SULT4A1,VAV2,PROX1,SMG7,NTM,ATN1,RASGRF1,ST8SIA3" Drug 3078_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.49E-07 3.08E-02 2.22E-04 2.43E-03 24 195 "CDHR1,ADORA1,HPCAL4,MOBP,ANK1,ANK3,APBA2,TAGLN3,SLN,NCAM1,ASTN2,GPM6B,NEURL1,TNS1,NRXN2,SULT4A1,ARHGEF4,CTNND1,STMN4,SMG7,RAD52,DSCAM,USH1C,ELAVL3" Drug CID000001248 AC1L1B1W Stitch 9.95E-07 3.23E-02 2.31E-04 2.53E-03 15 84 "ABAT,ADORA1,CSPG5,GAD2,ZEB1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,SULT4A1,BLOC1S6,DTNA,LRRC23" Drug 4773_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-06 3.38E-02 2.37E-04 2.60E-03 24 196 "FGF1,FGR,CDC42BPA,ATP1A2,COLGALT2,ALDH1L1,BTRC,WSCD1,GRM3,CELF3,SEZ6L,FADS2,CNTN1,IFFO1,POU3F4,NOS1AP,PHYHIP,ITIH2,PRDM2,KCND3,KCNJ9,KCNMA1,EFNA3,VWA5A" Drug 4461_UP fluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-06 3.38E-02 2.37E-04 2.60E-03 24 196 "MOBP,FOXG1,SLN,BRINP2,GAD2,ALDH1L1,RND1,CDK5R2,NPPA,GRIN1,INA,PAH,LILRA4,PDE4B,BEST1,NECAB2,EDRF1,TOX,SYNC,SRGAP3,RAD52,RASGRF1,DTNA,VWA5A" Drug ctd:D059808 Polyphenols CTD 1.04E-06 3.39E-02 2.37E-04 2.60E-03 41 455 "SERPINA3,CDHR1,ASIC4,FGR,HPCAL4,SELL,SH3GL2,GAS7,AQP4,SHANK2,CADPS,SCG3,DDX25,ATP1A3,SEPT3,SLCO1C1,GLS,GPR26,GRIN1,OLR1,CD81,CDC42,TPM3,PDE3B,PFKFB3,HPCA,CAMKV,CABP1,SLC25A27,NECAB2,POU3F2,PTPA,PPP3CB,NOS1AP,PTCH1,CEP170,KCNA2,KCNA4,SLC17A6,NUP214,RGS7" Drug CID000065749 13-methoxyibogamine Stitch 1.06E-06 3.46E-02 2.39E-04 2.62E-03 12 54 "FOXM1,SOX10,GFAP,CACNA1E,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,RET" Drug ctd:D004397 Fonofos CTD 1.11E-06 3.60E-02 2.39E-04 2.62E-03 56 714 "EPS8,RIMKLA,CDHR1,MBP,ADCY2,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug ctd:C045362 prochloraz CTD 1.11E-06 3.61E-02 2.39E-04 2.62E-03 29 268 "LRRC7,ERICH3,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,ASTN1,FYN,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,CHGA,DLGAP3,GDAP1L1,CADM1,NRXN1,NRXN2,NMT2,RGMA,MAGI2,DPP6,RET,CACNG7" Drug 3189_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ACTN2,FABP7,MOBP,TRIM46,ANK2,GAS7,BCO1,SLC6A9,SHANK2,ASCL1,SLCO1A2,ASTN1,MYH7,GLS,NHLH1,HAP1,GRIK2,PACSIN1,FAM131B,JAKMIP2,KCNMA1,RALGDS,DTNA,VWA5A" Drug 5905_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "CEND1,KCNIP2,KIAA1109,SEMA6A,FGR,RASA3,SLC1A7,BCO1,TNIK,CADM3,NMNAT2,CPLX2,NCAM1,TMEM151B,INA,KCNK10,SEZ6L,TMPRSS5,SULT4A1,VAV2,MAPK10,KCNJ4,TTLL7,RASGRP2" Drug 5605_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "DPF1,ASIC1,EMID1,ADCY2,FABP7,LRRTM4,FHL1,AMPH,ANK1,FYN,SOX10,NCAM1,WSCD1,NUMA1,BRSK2,CRB1,DAAM2,LILRA4,ADGRG1,CNTN1,FAM13C,SIDT2,VWA5A,RASGRP2" Drug 2873_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "EMID1,ARID1A,PLA2G6,SLC30A10,AMPH,RASA3,DOCK10,PKNOX2,SHANK2,SLN,IGSF9B,ATP2B2,NCDN,ATF7,CACNB2,NRGN,NEURL1,KCNK10,FADS2,PACSIN1,SNCAIP,ELMO1,RAD52,ATN1" Drug 2433_UP Felodipine [72509-76-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "SYNDIG1,ADORA1,KIAA1109,SEMA6A,HPCAL4,BCAS1,FXYD6,FGF17,GPM6A,ATP13A2,ZFYVE9,FLRT1,DZIP3,CTNND1,PLPPR1,PTHLH,CNIH3,KCNH1,RABGAP1L,DSCAM,NUP214,ST8SIA3,TTLL7,SEC61A2" Drug 6383_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "NDRG2,KIAA1109,FGF1,APC,BCAN,SHANK2,SORCS3,FYN,GAD2,INKA2,GNG3,CACNB2,CELF3,PAX6,NMT2,POU3F2,CRMP1,SDC3,FAM131B,PTPRD,KCNMA1,L1CAM,NUP214,EN2" Drug 3361_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "DPF1,ARID1A,NDRG2,AGT,KIAA1109,ASIC4,FHL1,APBA2,SLCO1A2,TAGLN3,ATP2B2,ZCCHC24,GAD2,NEUROD1,GLS,PSD3,PAX6,IFFO1,CRMP1,ATRNL1,RIMS3,KCNMA1,RAB3IL1,DTNA" Drug 4757_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ASIC1,FHL1,MOBP,FOXG1,AMPH,CDC42BPA,ANK2,BCAN,NLGN1,MSR1,TAGLN3,ZCCHC24,GAD2,GPR162,GNG3,TGFBR3,PTGDR2,VCAN,PKN2,PROX1,SYNC,PTCH1,KCNMA1,VWA5A" Drug 3820_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.14E-06 3.71E-02 2.39E-04 2.62E-03 24 197 "ASIC1,NLGN4X,AGT,FOXG1,AMPH,SORBS1,AQP4,BCO1,SLN,SORCS3,ATP2B2,CPLX2,NPAS3,RND1,ACSBG1,PRUNE2,NPPA,PDE2A,SULT4A1,KCND3,TMEM255A,RGS10,EFNA3,VWA5A" Drug 3810_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "FOXRED2,MOBP,AMPH,APC,SLC2A5,SHANK2,PDE8B,SLN,ATP1A2,ATP2B2,SOX10,CPLX2,ALDH1L1,INKA2,CDK5R2,USP2,TNFRSF1B,PDE3B,HPSE2,TUB,PLCH2,TOX,PTAFR,DNAH9" Drug 2234_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "DPF1,ASIC1,ASIC4,FHL1,MOBP,CDC42BPA,SLC1A7,PKNOX2,ASCL1,CCDC181,EMC1,RND1,NPPA,ADAMTS8,GRM3,TNS1,SEZ6L,SULT4A1,PACSIN1,SNCAIP,PROX1,SRGAP3,KCNMA1,RAD52" Drug 3671_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "EMID1,KIAA1109,MOBP,ANK2,SLC1A7,PDE8B,SLCO1A2,ATP1A2,SCN3B,ALDH1L1,GLS,VAMP1,ADAMTS8,PADI2,TNS1,PTGDR2,SEZ6L,ARHGAP22,CAMKV,IFFO1,RIMS3,PHYHIP,STMN4,KCNJ9" Drug 2867_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "RTN1,SLC30A10,ITSN1,MSR1,PKNOX2,DNAH17,WDTC1,NPAS3,NEUROD1,SLCO1C1,VAMP1,NPPA,ZEB1,NUMA1,DAAM2,CDH8,TPM3,GPR37L1,SERPINE2,CRMP1,MAGI2,DLG2,RAD52,ATN1" Drug 2472_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "MBP,SYNDIG1,RYR1,ADORA1,PLA2G6,PKP4,B3GAT1,ALDH4A1,CPLX2,PHLDB1,BTRC,GPM6B,ATF7,GRM3,ATP13A2,CDC42,RBFOX2,PRMT8,CHI3L2,ZFYVE9,ITIH2,CNIH3,PID1,ATN1" Drug 4358_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.25E-06 4.06E-02 2.52E-04 2.76E-03 24 198 "APC2,NDRG2,ADORA1,AGT,PLA2G6,APBA2,GAS7,RPH3A,SLC1A7,MSR1,CSPG5,TAGLN3,ADGRB2,ALDH1L1,WSCD1,TNS1,CDH8,SCRG1,CAMKV,CRMP1,CHD5,KCND3,LPAR6,EPB41" Drug 4458_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.26E-06 4.09E-02 2.52E-04 2.76E-03 22 171 "ABAT,TUBB4A,TESK2,SORBS1,BRINP2,FYN,RGL1,RND1,ACSBG1,GLS,KAZN,PCDH9,CADM1,NMT2,DNAJC12,PROX1,RIMS3,DNAJC6,JAKMIP2,PLPPR4,EFNA3,VWA5A" Drug CID000097812 decahydroisoquinoline Stitch 1.28E-06 4.16E-02 2.52E-04 2.76E-03 7 16 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug ctd:D000726 Androgen Antagonists CTD 1.31E-06 4.24E-02 2.52E-04 2.76E-03 14 75 "NLGN1,SLC1A6,SHANK2,GLS,CACNB2,SYT6,GRIA2,GRIA4,GRIK2,GRIN1,DLGAP3,NRXN1,NRXN2,MAGI2" Drug CID000003559 haloperidol Stitch 1.32E-06 4.28E-02 2.52E-04 2.76E-03 37 394 "ABAT,ADCY2,SLITRK1,AGT,FOXG1,FOXM1,SLC1A2,SOX10,GAD2,NPAS3,ABCC8,CACNA1A,CACNA1E,NPPA,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PAH,PDE4B,PDYN,NTSR2,CHRM1,PACSIN1,PTPA,PKN2,KCNA1,KCNA2,KCNA4,PTPRD,KCNH1,DTNA" Drug CID000040159 trans-permethrin Stitch 1.36E-06 4.41E-02 2.52E-04 2.76E-03 15 86 "ACHE,NDRG2,ADCY2,RYR1,SCN4B,API5,SCN3B,SOX10,GFAP,ASIC3,CP,KCNA1,KCNA2,CAMK1G,PHC2" Drug 4641_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ASIC1,FOXRED2,KIAA1109,FOXG1,CDC42BPA,SLC1A7,PDE8B,SLN,ASTN1,ATP2B2,TNIK,NDUFA5,OPCML,TGFBR3,CDC42,CDH10,SF1,SDC3,ARHGEF4,CTNND2,FAM131B,SMG7,PEX5,RGR" Drug 4359_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "FHL1,SLC30A10,SLC2A5,SLC14A1,FYN,ARPP21,PHLDB1,SLCO1C1,ABCC8,CACNB2,GRIK2,TNS1,CDH8,PCSK2,GPR37L1,SLC22A6,SULT4A1,VCAN,RIMS3,PTPRO,NTM,TTLL7,ELAVL3,RASGRP2" Drug 4648_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ACTN2,KIAA1109,FGF1,ANK1,SLC8A2,ASCL1,SNAP25,B3GALT2,MYH7,ADGRB2,ADAMTS8,P2RX7,CDH10,TPM3,GPR37L1,CABP1,KCNA2,KCNH1,KCNMA1,DSCAM,DTNA,ABCC9,RGR,RASGRP2" Drug 2526_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "CDHR1,ACTN2,LRRTM4,KIAA1109,ANK3,RASA3,SLCO1A2,CADM3,GAD2,NCAM1,GNG4,CAMSAP2,TCF7L2,GRIN1,PHKG1,NRXN2,CNTN1,KLK6,KCNC1,KCND3,KCNK1,SLC17A6,ABCC9,ROM1" Drug 5731_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "PRR5L,KLRC4,ASIC4,SELL,APBB1,APC,SLC1A7,WDTC1,ALDH1L1,GPM6A,OPCML,TNS1,PCSK2,PDE2A,TMPRSS5,CADM1,PTAFR,PLPPR1,KCND3,KCNJ4,RABGAP1L,KCNMA1,FAM13C,LMO1" Drug 2385_UP Cortisone [53-06-5]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "ADCYAP1R1,ADORA1,HPCAL4,MOBP,ZNF365,SLC1A7,PKNOX2,PDE8B,TNIK,CADM3,ALDH1L1,VAMP1,ATF7,GRM3,RBFOX2,CHRNB2,SULT4A1,MAPK8,PROX1,BRINP3,ITIH2,KCND3,SLC17A6,LRRC23" Drug 5526_UP Prednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "FHL1,HPCAL4,CDC42BPA,SYBU,ZSWIM8,ROBO3,GNG3,PRUNE2,WSCD1,CACNB2,CAMK2A,TNS1,PCSK2,FLRT1,VCAN,MAPK10,EDRF1,PLPPR1,HP1BP3,KCNMA1,ATG16L1,DTNA,EN2,LRRC23" Drug 5104_UP Flumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "DPF1,ADCY2,ADORA1,MOBP,RASA3,APBB1,APC,SORBS1,BCAS1,SLC2A5,SORCS3,ALDH4A1,CADM3,MLC1,MYRF,GPR19,GRIK2,TNS1,ADGRG1,NRXN2,IFFO1,CTNND2,AK5,RASGRP2" Drug 3759_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "TTYH1,MBP,SYNDIG1,PAQR6,NDRG2,AQP4,SLC2A5,INKA2,VAMP1,GNG4,NUMA1,BRSK2,GRIN1,GRM3,SEZ6L,PDE2A,NRXN1,CAMKV,PACSIN1,KCNA4,KCND3,ARNT2,RASGRF1,OLIG2" Drug 2506_UP Estropipate [7280-37-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-06 4.45E-02 2.52E-04 2.76E-03 24 199 "MAG,KCNIP2,ADCY2,ADORA1,HPCAL4,ANK3,AQP4,SLC6A9,SLN,ATP1A3,SOX10,NEUROD1,ASTN2,TCF7L2,GRIA4,GRIN1,ADAMTS8,USP2,PHKG1,NRXN2,CABP1,RIMS3,KCND3,ST8SIA3" Drug CID000037165 saxitoxin Stitch 1.37E-06 4.46E-02 2.52E-04 2.76E-03 13 65 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ANK2,SCN3B,MYH7,NKX6-2,NEUROD1,TF,ASIC3,SLC25A18" Drug 5217_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-06 4.52E-02 2.54E-04 2.79E-03 22 172 "ADD3,TUBB4A,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,VWA5A" Drug 3528_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.50E-06 4.87E-02 2.70E-04 2.96E-03 24 200 "NDRG2,AQP4,SLCO1A2,DNAH17,ALDH1L1,RND1,GNG4,BTRC,WSCD1,NPPA,CACNB2,PSD3,GRIA1,GRIN1,OLR1,CDH10,ADGRG1,PLEKHB1,VAV2,NECAB2,OSBPL3,PSD,ATN1,RASGRP2" Drug 3833_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.50E-06 4.87E-02 2.70E-04 2.96E-03 24 200 "CEND1,NDRG2,ADCY2,SELL,SLC2A5,ASPH,BRINP2,ATP2B2,NEUROD1,ATF7,USP2,PTGDR2,PDE3B,CHRNB2,FADS2,SNCAIP,PTHLH,ITIH2,TMCC2,NKAIN1,PID1,VWA5A,ELAVL3,EN2" Drug ctd:D010406 Penicillins CTD 1.51E-06 4.91E-02 2.70E-04 2.96E-03 6 11 "SLC1A2,MT3,CAMK2A,GRIA1,GRIA2,PLPPR1" Drug CID005039877 sym 2206 Stitch 1.51E-06 4.91E-02 2.70E-04 2.96E-03 6 11 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug ctd:D003633 Dichlorodiphenyl Dichloroethylene CTD 1.60E-06 5.19E-02 2.84E-04 3.11E-03 31 303 "LRRC7,FOLH1,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,BCL2L2,GFRA1,GJB1,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,TF,CD81,TNFRSF1B,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,PTCH1,MAGI2,DPP6,RET,CACNG7" Drug ctd:D008694 Methamphetamine CTD 1.67E-06 5.44E-02 2.96E-04 3.24E-03 92 1407 "PRR5L,MAPT,MBP,SYT9,LGR4,ARID1A,SLC25A25,F3,CLIP1,PLEKHG5,FABP7,ADORA1,ADORA3,SH3GL2,DGKZ,TACC2,SORBS1,SLC1A2,SLC2A5,SLC6A9,MT3,LGI3,TAGLN3,SORCS3,SNCB,FYN,PALLD,GAD2,MYH7,NKX6-2,TTLL9,ADAM15,CPLX2,BCL2L2,NDUFA5,GFAP,PHLDB1,SEPT3,AJAP1,GLS,ZNF638,ASTN2,CNTN2,GOLGB1,PRUNE2,ACSL6,NEU4,GPR17,GPR19,PSD3,GRIA1,GRIA2,GRIN1,GRM3,PTPN5,TIE1,TNS1,MAGI1,PDE2A,PDE4B,PDYN,ZMYND8,SCRG1,ASIC3,HPCA,PHKG1,MICAL1,PACSIN1,PPP3CB,PUM1,HES5,DPYSL5,ANKS1B,GON4L,PMEPA1,PRDM2,ZC3H11A,AK5,KCNJ4,KCNJ9,ARNT2,SNX27,CAB39L,HS3ST4,RAD52,FAM57B,USH1C,SLC39A12,SIDT2,PLEKHO1,EPB41L1,RASGRP2" Drug ctd:C012568 terbufos CTD 1.71E-06 5.54E-02 3.00E-04 3.28E-03 56 724 "EPS8,RIMKLA,CDHR1,MBP,ADCY2,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug CID000001140 toluene Stitch 1.87E-06 6.06E-02 3.26E-04 3.57E-03 22 175 "ASIC1,SCN3A,SCN4B,SCNN1D,LRRC7,ASIC4,LRRC4C,SCN3B,AHCYL1,DNER,NDUFA5,GFAP,NODAL,LEFTY2,PAX6,ASIC3,ANLN,PRKCG,PKN2,PRKCZ,CDH20,ROM1" Drug CID000127988 "4,6-dichloroindole-2-carboxylic acid" Stitch 1.93E-06 6.27E-02 3.35E-04 3.67E-03 5 7 "B3GAT1,GRIA1,GRIA2,GRIA4,GRM3" Drug ctd:D009538 Nicotine CTD 1.98E-06 6.44E-02 3.43E-04 3.76E-03 71 1005 "ACHE,MBP,SYT9,LDLRAD3,ARID1A,F3,ADCYAP1R1,GRAMD1B,TUBB4A,HPCAL4,SFPQ,RASA3,NTNG1,BCAS1,API5,CLSTN1,AQP4,RPH3A,MADD,MT3,CCDC88A,CGREF1,ADGRA1,ATM,FYN,KIF21B,ARPP21,NPAS3,NCAM1,NDUFA5,GFAP,PHLDB1,ARHGEF7,SYT4,DDHD2,ACSL6,ZEB1,PTBP2,EML4,CAMK2A,GRIK2,GPR88,TJP1,CDC42,ZMYND8,ADGRG1,CHGA,CHRNB2,HPCA,OPALIN,CCDC136,CNTN1,FEZ1,VCAN,CMTM5,PKN2,PRKCZ,IGSF1,MAPK8,PROX1,PTAFR,ITGAV,HP1BP3,MED24,KCND3,AK5,KCNK1,SLC25A48,SLC17A6,ST8SIA3,RLBP1" Drug 2375_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.12E-06 6.89E-02 3.64E-04 4.00E-03 23 190 "NDRG2,F3,ADD3,ADORA1,ATP2B2,ZCCHC24,CADM3,NCAM1,RGL1,CAMSAP2,MYRF,NRGN,GRIN1,JAM2,BEST1,CRMP1,DZIP3,CTNND1,RIMS3,DNAJC6,EFNA3,VWA5A,EPB41L1" Drug CID000003837 AC1L1GTT Stitch 2.22E-06 7.22E-02 3.80E-04 4.17E-03 26 233 "MBP,KCNIP2,RYR1,AGT,SNAP25,MYBPC1,CACNB2,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRM3,P2RX7,HMGB1,SLC22A6,CAMKV,CHD1L,PTPA,PRKACB,PRKCG,KCNC1,KCND3,KCNJ4,CAMK1G,NUP214" Drug 3395_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ZEB1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug 7324_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SYBU,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,VAMP1,PADI2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,NAV2,EFNA3" Drug 6493_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.26E-06 7.34E-02 3.80E-04 4.17E-03 22 177 "ADD3,TUBB4A,PPM1E,SORBS1,SYBU,PKNOX2,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,ZEB1,PADI2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,VWA5A" Drug CID000003598 hexachlorophene Stitch 2.46E-06 8.00E-02 4.12E-04 4.52E-03 15 90 "PLA2G6,MOBP,CCDC88A,SCG3,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CDH8,ANKS1B" Drug 3332_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.54E-06 8.25E-02 4.23E-04 4.64E-03 23 192 "TUBB4A,FHL1,C1orf61,AMPH,RASA3,PKNOX2,FYN,WDTC1,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,ABCC8,OMG,CCKBR,USP2,CHI3L2,PIK3CD,DNAJC12,KCND3,TMCC2,ST8SIA3" Drug CID004223812 sunifiram Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID009964065 3-isoxazolol Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011105661 4-(chloromethyl)-3-methoxy-5-methylisoxazole Stitch 2.59E-06 8.41E-02 4.25E-04 4.66E-03 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID006857345 AC1OAGFB Stitch 2.64E-06 8.57E-02 4.31E-04 4.72E-03 45 540 "ASIC1,ADCY2,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,AMPH,RASA3,SH3GL2,DGKZ,DGKD,RPH3A,ARFGAP1,SCN3B,ABCC8,GNAS,GNG3,KCNK10,REPS2,CDC42,ASIC3,CHRM1,TUB,PIK3CD,SDC3,PRKCG,PKN2,PRKCZ,SYTL2,PLPPR5,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ9,KCNJ10,KCNQ2,DNM2,RASGRF1,BSCL2,EPB41,EPB41L1,EPB41L2,RASGRP2" Drug 2794_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.73E-06 8.86E-02 4.43E-04 4.86E-03 22 179 "ADD3,TUBB4A,HPCAL4,PPM1E,SORBS1,ZNF365,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,POPDC3,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,VWA5A" Drug CID000002252 Atpa Stitch 2.92E-06 9.48E-02 4.72E-04 5.17E-03 6 12 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug CID000004914 procaine Stitch 2.96E-06 9.61E-02 4.76E-04 5.22E-03 20 153 "ASIC1,ACHE,RYR1,TUBB4A,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CACNA1A,CACNA1E,CACNB2,ASIC3,CHRM1,CHRNB2,PRKCG,PKN2,PRKCZ,TUBB2B,CACNG7" Drug 4260_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.04E-06 9.86E-02 4.86E-04 5.33E-03 23 194 "ABAT,ACHE,RYR1,MOBP,RASA3,SORBS1,SLC1A6,ASCL1,INKA2,NEUROD1,NUMA1,TF,USP2,PDE3B,ADGRG1,CHI3L2,DUSP26,CABP1,RGS6,PRDM2,KCNC1,RASGRF1,PAK5" Drug 2881_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.28E-06 1.07E-01 5.18E-04 5.68E-03 22 181 "TUBB4A,SEMA6A,SORBS1,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,WSCD1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,JAKMIP2,MAGI2,TTLL7,EFNA3,VWA5A,RASGRP2" Drug 2504_UP Skimmianine [83-95-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "MAG,ACHE,KCNIP2,ADCY2,MOBP,SORBS1,SHANK2,PDE8B,SLCO1A2,TAGLN3,SLN,ATP1A3,GAD2,ARPP21,CDK5R2,BTRC,GRIA4,KCNK10,PRMT8,RGS6,ZBTB16,KCNJ4,ST8SIA3" Drug 4971_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "NDRG2,FGF1,WDTC1,ALDH1L1,RND1,POPDC3,KAZN,BTRC,WSCD1,GPM6B,CACNB2,TCF7L2,NUCB1,CCKBR,ZMYND8,CNTN1,NECAB2,VCAN,EDRF1,RIMS3,SSPN,SIDT2,VWA5A" Drug 6159_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "NDRG2,PLA2G6,FHL1,MOBP,CDC42BPA,SHANK2,GPR153,ACSBG1,GLS,ROBO3,WWC1,WSCD1,HAP1,CRB1,CHGA,CHRNB2,BEST1,MAPK10,KCNMA1,CRTAC1,SIDT2,EFNA3,RASGRP2" Drug 2566_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.31E-06 1.08E-01 5.18E-04 5.68E-03 23 195 "CEND1,NDRG2,FHL1,PPM1E,B3GAT1,PALLD,TNIK,RAP1GAP2,NCAM1,RGL1,PHLDB1,VAMP1,GPR19,INA,PADI2,FLRT1,FEZ1,DZIP3,EDRF1,RIMS3,DNAJC6,TTLL7,ABI2" Drug CID000009238 adamantane Stitch 3.42E-06 1.11E-01 5.32E-04 5.83E-03 10 41 "FOLH1,NEU4,GRIA1,GRIA2,GRIA4,GRM3,P2RX7,TNS1,MED1,CTNND1" Drug CID000002548 AC1L1DXE Stitch 3.49E-06 1.13E-01 5.32E-04 5.83E-03 30 299 "ACHE,RYR1,ADORA1,SCNN1D,ACTL6B,ANK1,ANK2,ANK3,FOLH1,B3GAT1,GFAP,CACNA1A,CACNA1E,CACNB2,GRIK3,GRIK4,CCKBR,HRH3,PDYN,CHGA,ASIC3,CHRM1,PIK3CD,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PYGM,CACNG7" Drug CID000000942 Nicorette Stitch 3.57E-06 1.16E-01 5.32E-04 5.83E-03 44 529 "ASIC1,ACHE,F3,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,CCDC80,SLC8A2,GABBR1,SCN3B,GFAP,GFRA1,NODAL,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,LEFTY2,ZFP91,PDYN,HAPLN2,HMGB1,CHGA,ASIC3,CHRM1,CHRNB2,PIK3CD,ACBD5,PRKACB,PRKCG,PKN2,PRKCZ,PSMD13,KCNC1" Drug CID005311098 Ns102 Stitch 3.58E-06 1.16E-01 5.32E-04 5.83E-03 8 25 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,MAPK8,MAPK10" Drug 4453_UP clozapine; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,ACTN2,SCNN1D,MOBP,PPM1E,DDX25,ATP2B2,KIF21B,CADM3,GAD2,NCAM1,NEUROD1,GNG4,ADGRL3,GRIA4,HPCA,CAMKV,EDRF1,TOX,RABGAP1L,ARNT2,ATN1,DSCAM" Drug 5740_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,EMID1,KIAA1109,FOXG1,DOCK10,GAS7,AQP4,PKNOX2,TAGLN3,ADGRB2,GPM6A,ATF7,NPPA,EML4,GRIN1,OPCML,PLEKHB1,SPATA6,SRGAP3,AK5,ST8SIA3,EN2,RASGRP2" Drug 3375_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "DPF1,TUBB4A,FHL1,C1orf61,AMPH,GAS7,RPH3A,SHANK2,DLL3,ASPH,SLN,NDUFA5,AJAP1,ZEB1,TNS1,CDH8,CHI3L2,SULT4A1,SNCAIP,TOX,RABGAP1L,KCNMA1,ELAVL4" Drug 3369_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "CEND1,ACTN2,NDRG2,ADCY2,GAS7,SLC6A9,SHANK2,SLCO1A2,IGSF9B,ATP1A3,WSCD1,DAAM2,TNS1,CDH8,LILRA4,PDE1C,ZFYVE9,PIK3CD,SULT4A1,PTAFR,ITIH2,MAGI2,TMCC2" Drug 2501_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "TUBB4A,ANK3,PPM1E,APC,SLCO1A2,SLN,SNAP25,GAD2,SPART,BCL2L2,FAM168A,BTRC,NPPA,ZEB1,NUCB1,ATP13A2,OMG,CDH10,TPM3,SULT4A1,CNTN1,MAGI2,DTNA" Drug 6169_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "CHST15,PLA2G6,ASIC4,CDC42BPA,SHANK2,GPR153,SLCO1A2,ASTN1,CPLX2,SLCO1C1,ASTN2,BTRC,GPM6B,GPR19,OPCML,TPM3,ZMYND8,ASIC3,MICAL2,AK5,ATN1,DSCAM,NUP214" Drug 3604_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "MBP,SYNDIG1,NDRG2,FABP7,GRAMD1B,SELL,AMPH,SORBS1,SHANK2,ATP2B2,GAD2,RND1,POPDC3,GNG3,INA,PACSIN1,POU3F4,MICAL2,MASP1,PTAFR,KCND3,DPP6,RASGRP2" Drug 3726_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "ACTN2,NDRG2,ADORA1,FGF1,TRIM46,APBB1,ASPH,ALDH4A1,SCN3B,TNIK,KIF21B,SLCO1C1,GPR19,USP2,TNS1,PDE2A,PDE4B,CHI3L2,CHRNB2,SULT4A1,EDRF1,PRDM2,DSCAM" Drug 3696_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-06 1.18E-01 5.32E-04 5.83E-03 23 196 "ACTN2,FGR,C1orf61,APBB1,RPH3A,CGREF1,SLCO1A2,BRINP2,MYH7,GNAS,KLHL4,GPM6A,ZEB1,GRM3,TPM3,MAGI1,CHI3L2,RIMS3,PTPRO,NKAIN1,ABCC9,RGS7,RAVER2" Drug 1000_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.83E-06 1.25E-01 5.41E-04 5.94E-03 21 169 "ADD3,TUBB4A,GPR153,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,PCDH9,PIK3CD,DNAJC12,MAPK8,KIAA0513,RIMS3,PTCH1,DNAJC6,JAKMIP2,EFNA3" Drug 4226_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ARID1A,ADORA3,MOBP,ANK3,PKP4,NTNG1,MSR1,TNIK,NFASC,WWC1,CACNB2,GPR17,OLR1,NEURL1,REPS2,MAGI1,PDE3B,CA14,SULT4A1,NECAB2,IFFO1,FEZ1,SRGAP3" Drug 6614_UP Apramycin [37321-09-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "KCNIP2,ADORA1,ANK1,AQP4,BRINP2,CCDC181,ATP2B2,SOX10,SLCO1C1,PRUNE2,GRIA1,NEURL1,CA14,SPATA6,IFFO1,CHD5,CTNND2,ECE2,PROX1,PTCH1,RAB3IL1,DNAH9,VWA5A" Drug 6514_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ACTN2,TUBB4A,FHL1,ANK1,GAS7,SLC1A7,MSR1,ADAM15,PHLDB1,AJAP1,GLS,GNAS,GRIK2,USP2,ZFYVE9,KIAA1549L,CAMKV,RGS6,VCAN,PROX1,HP1BP3,DTNA,RCAN2" Drug 6423_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ARID1A,NLGN4X,SCN3A,SH3GL2,ZCCHC24,EMC1,NPAS3,NEUROD1,GPM6A,ATF7,CACNB2,GRM3,GUCY1A2,PCDH9,SEZ6L,ZMYND8,SCRG1,PRRX1,CHD1L,MAPK8,EDRF1,PTCH1,DTNA" Drug 4642_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "FOXRED2,APC,SLC1A7,SLC6A9,ASTN1,FYN,ATP2B2,CADM3,EMC1,ADGRB2,NEUROD1,GLS,BTRC,ADGRL3,GRIK2,GPR37L1,CHI3L2,CADM1,CABP1,DTNA,ST8SIA3,RGR,RGS10" Drug 5616_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "DPF1,MAG,EXTL1,RYR1,MOBP,C1orf61,RPH3A,ASCL1,NMNAT2,NPAS3,GFAP,MLC1,POPDC3,PRUNE2,GRIA1,ADAMTS8,PCDH9,HPSE2,MICAL1,NECAB2,MAPK8,NOS1AP,PTAFR" Drug 4229_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "TTYH1,ABAT,SLC8A2,ASCL1,MYH7,NCAM1,NEUROD1,VAMP1,ADGRL3,PRUNE2,ADAMTS8,PHKG1,CADM1,NRXN2,BEST1,NOS1AP,PRDM2,KCNC1,SRGAP3,CAMK1G,ST8SIA3,RGR,LRRC23" Drug 4631_DN Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "MAPT,FOXG1,SLC1A7,SLC14A1,PDE8B,ATP2B2,CADM3,ADGRB2,NEUROD1,BTRC,ADGRL3,CACNA1A,OPCML,TNS1,CDH10,NMT2,CTNND2,SMG7,PEX5,RAB3IL1,ATG16L1,ATN1,RGR" Drug 2511_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "AGT,BCAR3,SLCO1A2,TAGLN3,B3GAT1,ALDH4A1,ATP1A2,ATP1A3,MYBPC1,GAD2,ACSBG1,TCF7L2,CAMK2A,BRSK2,ADAMTS8,GUCY1A2,TLL2,CTNND1,RIMS3,KCNC1,AK5,DLG3,TTLL7" Drug 5953_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "ACTN2,WLS,NDRG2,ADORA1,PLA2G6,SLC1A7,BRINP2,EMC1,PHLDB1,GNG4,BTRC,GPR19,GRIN1,TF,NECAB2,PTHLH,KCND3,KCNJ4,PEX5,DTNA,EFNA3,EN2,LRRC23" Drug 6715_UP Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "MOBP,PKP4,NTNG1,PKNOX2,MYH7,INKA2,SLCO1C1,GPM6B,GRIK2,TNS1,PTGDR2,NMT2,PMP2,IFFO1,ATRNL1,MAPK8,PROX1,PTCH1,AK5,ST8SIA3,SIDT2,OLIG2,RASGRP2" Drug 2864_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "DPF1,EMID1,ADORA1,PLA2G6,SLC1A7,BCO1,PKNOX2,TAGLN3,WDTC1,NEUROD1,GLS,NPPA,CACNB2,CAMK2G,ADAMTS8,OPCML,ZFYVE9,PIK3CD,PACSIN1,RIMS3,PTCH1,ITIH2,TMCC2" Drug 3513_UP Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "C1orf61,APBA2,SYBU,BCO1,BRINP2,COLGALT2,RND1,GNAS,BTRC,HAP1,NUCB1,PSD3,PDE1C,PDE3B,ADGRG1,FADS2,SDC3,MAPK10,EDRF1,NOS1AP,ATN1,DSCAM,DTNA" Drug 3694_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.94E-06 1.28E-01 5.41E-04 5.94E-03 23 197 "PAQR6,GRAMD1B,MOBP,ANK1,DOCK10,APC,SHANK2,ASPH,ATP1A3,MLC1,BTRC,GPM6B,CRB1,SPX,PDE2A,SULT4A1,SYTL2,PHYHIP,PRDM2,PTPRO,NTM,ARNT2,RALGDS" Drug ctd:C109476 epoxiconazole CTD 3.95E-06 1.28E-01 5.41E-04 5.94E-03 33 348 "FGF1,PLA2G6,LRRC7,ANXA7,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,FYN,FAM168A,GLS,CACNA1A,CAMK2G,GRIA2,GRIA4,GRIK2,GRIN1,CD81,PC,CHGA,DLGAP3,CADM1,NRXN1,NRXN2,ETNPPL,CHD1L,FEZ2,SIRPA,ITIH2,MAGI2,DPP6,CACNG7" Drug CID000005917 pentylenetetrazol Stitch 4.02E-06 1.31E-01 5.49E-04 6.02E-03 18 130 "ABAT,ACLY,ADGRV1,ADORA1,ADORA3,GAD2,GFAP,ZEB1,GRIA1,GRIA2,GRIA4,GRM3,HRH3,PDYN,SLC36A4,TOX,PTCH1,KCNA1" Drug CID000105153 rubidium Stitch 4.18E-06 1.36E-01 5.54E-04 6.07E-03 12 61 "AGT,SLC14A1,ATP1A2,ATP1A3,DDR1,P2RX7,KCNA4,KCNC1,KCNJ4,KCNJ9,KCNJ10,KCNMA1" Drug 6736_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.21E-06 1.37E-01 5.54E-04 6.07E-03 21 170 "DPF1,ABAT,MAPT,CEND1,TUBB4A,SORBS1,BRINP2,FYN,TNIK,RGL1,GLS,USP2,REPS2,PCDH9,DNAJC12,KIAA0513,SYTL2,DNAJC6,PLPPR4,SRGAP3,EFNA3" Drug 1522_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "DPF1,EMID1,RYR1,ADORA1,MOBP,ITSN1,DOCK10,SLC1A7,GPR153,ATP1A3,ZCCHC24,SPART,POPDC3,CACNA1A,PRUNE2,ZEB1,NUMA1,PIK3CD,VAV2,ITIH2,MAGI2,KCNK2,RAD52" Drug 1466_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "C1orf61,BCAN,BCAS1,GPR153,DLL3,ASPH,GNG3,HAP1,USP2,CDC42,CDH10,ZMYND8,MICAL1,PACSIN1,CRMP1,SDC3,RIMS3,PHYHIP,PLPPR1,PTHLH,PRDM2,KCNMA1,ATN1" Drug 6843_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "EMID1,RYR1,KIAA1109,SEMA6A,FHL1,C1orf61,SELL,RASA3,CCDC88A,SLCO1A2,FYN,ZCCHC24,AJAP1,MLC1,VAMP1,WSCD1,HAP1,GRIN1,ADGRG1,POU3F4,CHD5,RABGAP1L,KCNMA1" Drug 4346_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "SLC30A10,MOBP,GAS7,SORBS1,CPLX2,SPART,SLCO1C1,POPDC3,ATF7,GRM3,OPCML,CELF3,KCNK10,TNS1,CDH8,MASP1,KCND3,SRGAP3,ATN1,RASGRF1,FAM13C,LMO1,ELAVL3" Drug 3092_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "SYNDIG1,ADORA1,BCAR3,FHL1,AMPH,PKNOX2,PDE8B,SLN,TNIK,GNG4,OMG,TJP1,NEURL1,TNS1,PCDH9,PDE1C,ZFYVE9,VAV2,CNTN1,POU3F2,POU3F4,SYTL2,ATN1" Drug 3612_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "KIAA1109,APC,GPR153,SNAP25,ATP2B2,SOX10,GAD2,NEUROD1,RND1,ACSBG1,BTRC,INA,CDC42,PTGDR2,ZFYVE9,NECAB2,POU3F2,VCAN,PTAFR,CA10,SRGAP3,TTLL7,OLIG2" Drug 2279_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "MBP,TUBB4A,KIAA1109,APC,SLC1A2,SLC2A5,DLL3,FYN,PHLDB1,ROBO3,PSD3,NEURL1,TNS1,VAV2,CABP1,POU3F4,CRMP1,PLCH2,ITIH2,KCND3,ATN1,ST8SIA3,RASGRP2" Drug 5916_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "CEND1,MOBP,CDC42BPA,APC,GAS7,ZNF365,SLC2A5,ASCL1,BRINP2,FYN,ZCCHC24,GLS,TGFBR3,TNS1,PDE1C,PDE3B,CA14,RIMS3,PARD6A,KCNMA1,DTNA,SSPN,ELAVL3" Drug 2269_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ACTN2,ARID1A,MOBP,C1orf61,SLC1A2,PDE8B,ATP2B2,CADM3,SOX10,SPART,ALDH1L1,FGF17,RND1,ABCC8,GLS,ADGRL3,WSCD1,TGFBR3,PRMT8,VCAN,SDC3,PTHLH,CRTAC1" Drug 3196_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "MAPT,ADORA1,FOXG1,MSR1,SHANK2,SLCO1A2,ASTN1,ATP1A2,RND1,SLCO1C1,ADGRL3,GPM6A,GPM6B,HAP1,GRIN1,GRM3,NMT2,IFFO1,MICAL2,VCAN,RIMS3,USH1C,VWA5A" Drug 4101_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ABAT,ADCY2,FOXRED2,AGT,ST8SIA1,AQP4,MSR1,BRINP2,MYT1L,PRUNE2,DDR2,PDE2A,CHI3L2,CABP1,SPATA6,POU3F2,RGS6,MICAL2,NOS1AP,PRDM2,DSCAM,RGR,EPB41" Drug 4650_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.30E-06 1.40E-01 5.54E-04 6.07E-03 23 198 "ABAT,ACTN2,FABP7,SELL,DNAH17,B3GALT2,MYH7,GRIK3,OLR1,USP2,P2RX7,CDH10,ST8SIA5,SULT4A1,CABP1,SPATA6,POU3F2,RGS6,KCND3,KCNH1,RABGAP1L,ATN1,CAMK1G" Drug CID000093460 pyraclofos Stitch 4.40E-06 1.43E-01 5.63E-04 6.17E-03 16 106 "SCN4B,ANK2,SCN3B,CACNA1A,CACNB2,ASIC3,CHRM1,PRKCG,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND3,KCNH1,CACNG7" Drug ctd:D011188 Potassium CTD 4.40E-06 1.43E-01 5.63E-04 6.17E-03 16 106 "ADORA1,AGT,SHANK2,ABCC8,KCNK10,PDYN,MAPK8,KCNC1,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNQ2,ABCC9" Drug CID005459389 DB04780 Stitch 4.62E-06 1.50E-01 5.78E-04 6.34E-03 21 171 "MAG,MBP,F3,MOBP,MOG,SELL,BCAN,ST8SIA1,B3GAT1,GFAP,ADAMTS8,OMG,TNR,HMGB1,PMP2,VCAN,PRKCG,PKN2,PRKCZ,ARHGEF4,KLK6" Drug 1373_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "MBP,SEMA6A,C1orf61,PPFIA1,CADM3,ADGRB2,GJB1,PHLDB1,GLS,GNG4,CACNA1A,NPPA,OMG,KCNK10,ZMYND8,CHRNB2,DUSP26,SERPINE2,CAMKV,PACSIN1,CRMP1,TMCC2,DLG3" Drug 4008_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "MAPT,KCNIP2,PLA2G6,FGF14,HPCAL4,SNCB,CADM3,ZSWIM8,ADGRB2,PHLDB1,BTRC,GPM6B,ZEB1,NEURL1,CDC42,MAGI1,RGS6,PTCH1,KCNC1,BEND5,DTNA,ABCC9,USH1C" Drug 3557_UP Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "EMID1,NDRG2,RTN1,FHL1,AMPH,APBA2,GPR153,SLN,ALDH4A1,ATP1A3,DKK3,RND1,WSCD1,NPPA,PC,TNS1,GPR37L1,PMP2,ATRNL1,PLPPR1,RLBP1,SSPN,EFNA3" Drug 4532_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "ACHE,MDM4,FGF1,HPCAL4,RASA3,BCAN,SCN3B,TNIK,ACSBG1,VAMP1,PRUNE2,HAP1,PDE2A,CHI3L2,CHRNB2,CCSER2,NECAB2,CTNND2,KCNC1,RABGAP1L,RASGRF1,ST8SIA3,EPB41" Drug 4259_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "ARID1A,AGT,AQP4,SLC1A6,ASCL1,SLCO1A2,SNAP25,CCDC181,ATP1A2,NFASC,INKA2,GRIK3,P2RX7,PTGDR2,NRXN1,CABP1,NOS1AP,KCNH1,SUSD4,ABCC9,CAMK1G,RGR,RASGRP2" Drug 6458_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "SEMA6A,FHL1,BCAN,SLC1A7,ATM,WDTC1,EMC1,BCL2L2,BTRC,CACNA1A,NUDT21,PC,RBFOX2,PIK3CD,MICAL1,SYNC,HP1BP3,TMCC2,DTNA,EFNA3,RBM12,VWA5A,EPB41L2" Drug 6652_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "KLRC4,ADORA3,ANK2,GAS7,MSR1,SLC6A9,DDX25,CADM3,INKA2,KLHL4,SEZ6L,PDE3B,PDE4B,HPSE2,TUB,VAV2,SPATA6,KCND3,SLC17A6,FAM13C,DTNA,CRTAC1,RASGRP2" Drug 5997_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.68E-06 1.52E-01 5.78E-04 6.34E-03 23 199 "SYNDIG1,MDM4,FHL1,SELL,CDC42BPA,GAS7,BCO1,PKNOX2,DDX25,SNAP25,GAD2,GFAP,RGL1,NEUROD1,VAMP1,BRSK2,TNS1,MICAL1,CRMP1,RGR,TTLL7,EFNA3,RASGRP2" Drug CID003016733 1-hydroxypyrazole Stitch 4.98E-06 1.62E-01 6.06E-04 6.64E-03 5 8 "SLC1A2,GRIA1,GRIA2,GRIA4,GRM3" Drug CID003614351 1-hydroxyimidazole Stitch 4.98E-06 1.62E-01 6.06E-04 6.64E-03 5 8 "SLC1A2,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000004853 Pirmenolum Stitch 4.99E-06 1.62E-01 6.06E-04 6.64E-03 8 26 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1" Drug CID000219078 lacosamide Stitch 5.00E-06 1.62E-01 6.06E-04 6.64E-03 11 52 "ABAT,ADGRV1,SCN4B,SEMA6A,SCN3B,GRIA1,GRIA2,GRIA4,ASIC3,SV2A,KCNQ2" Drug 5580_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.07E-06 1.65E-01 6.06E-04 6.64E-03 21 172 "ADD3,TUBB4A,SORBS1,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,CDK5R2,USP2,PCDH9,PIK3CD,DNAJC12,DNAJC6,JAKMIP2,SRGAP3,EFNA3" Drug CID000656723 LY382884 Stitch 5.08E-06 1.65E-01 6.06E-04 6.64E-03 7 19 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000071249 diprafenone Stitch 5.08E-06 1.65E-01 6.06E-04 6.64E-03 7 19 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug 3623_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "MAPT,ACTN2,KIAA1109,ASIC4,FHL1,SLCO1A2,TNIK,SOX10,CPLX2,GRIA4,GRIK2,OMG,KCNK10,ZFYVE9,POU3F2,CHD5,PHYHIP,ELMO1,SMG7,SRGAP3,KCNMA1,RAD52,OLIG2" Drug 3752_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "CDHR1,APC2,FABP7,KIAA1109,PKP4,NEUROD1,RND1,SLCO1C1,ADGRL3,NUMA1,BRSK2,PCDH9,PDE3B,SULT4A1,IFFO1,FEZ1,MAPK10,MASP1,PTAFR,ATN1,RASGRF1,RGS10,EFNA3" Drug 604_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.09E-06 1.65E-01 6.06E-04 6.64E-03 23 200 "GRAMD1B,KIAA1109,PLA2G6,ITSN1,APC,USP33,CADM3,ZSWIM8,NMNAT2,GNG4,TMEM151B,RBFOX2,SEZ6L,PIK3CD,VAV2,CRMP1,SDC3,IGSF1,PLPPR1,JAKMIP2,ITIH2,KCND3,SIDT2" Drug 2202_UP Gossypol [303-45-7]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.14E-06 1.67E-01 6.09E-04 6.68E-03 22 186 "CLIP1,RYR1,ASIC4,HPCAL4,CDC42BPA,PPM1E,RPH3A,PKNOX2,SLN,FYN,SOX10,NPAS3,NPPA,P2RX7,FLRT1,CNTN1,BEST1,NECAB2,PSD,RIMS3,KCND3,DSCAM" Drug CID000129695 Naspm Stitch 5.24E-06 1.70E-01 6.19E-04 6.79E-03 6 13 "B3GAT1,NASP,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000119582 Joro spider toxin Stitch 5.45E-06 1.77E-01 6.39E-04 7.01E-03 10 43 "NASP,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,NUP214" Drug CID000126756 LY 300164 Stitch 5.45E-06 1.77E-01 6.39E-04 7.01E-03 10 43 "FOLH1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,ZFP91,SV2A,KCNQ2" Drug 4112_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.56E-06 1.81E-01 6.50E-04 7.13E-03 21 173 "ADD3,TUBB4A,SORBS1,PKNOX2,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,DNAJC12,DNAJC6,EFNA3,VWA5A" Drug CID000440805 2-amino-5-oxohexanoate Stitch 5.58E-06 1.81E-01 6.50E-04 7.13E-03 18 133 "ADGRV1,FGF1,GFAP,NEUROD1,CNTN2,ZFP91,PAX6,TUB,VCAN,NCAN,RGMA,SV2A,PCDH15,KCNN3,RLBP1,ELAVL3,OLIG2,RPE65" Drug CID000001650 AC1L1BXF Stitch 6.12E-06 1.99E-01 7.10E-04 7.78E-03 14 85 "DGKZ,DGKD,SLC1A2,SLC1A6,SLC1A7,GFAP,MLC1,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,HMGB1,PLPPR5" Drug ctd:C044887 beta-methylcholine CTD 6.39E-06 2.08E-01 7.39E-04 8.10E-03 102 1657 "RABEPK,ASIC1,MAPT,CEND1,ADAR,RTN1,GALNT13,ADD3,CDC7,SORCS1,FOXRED2,SEMA6A,HPCAL4,TRIM46,ITSN1,PKP4,GPAM,ZCCHC17,TACC2,PAAF1,CLSTN1,MIER1,URGCP,NBPF1,ARFGAP2,ASCL1,ARFGAP1,SNAP25,ATM,FYN,PHYHIPL,USP33,SON,NMNAT2,GART,RAP1GAP2,NCAM1,LMO3,ZNF302,GPR162,NELL1,PHLDB1,ARHGEF7,VAMP1,CASTOR3,SYT4,POPDC3,CAMTA1,PSRC1,TCF12,NRDC,CAMK2G,DDR2,NUMA1,GRIN1,FBXL16,GUCY1A1,CELF3,DCLK1,TPM3,TPM4,FNDC5,CHGA,PFKFB3,TUB,HNRNPK,NOMO2,ANLN,UBTF,DNAJC12,CCDC136,IFFO1,SF1,RNF14,CRLS1,PPP3CB,FEZ1,RIMS4,PLD5,PRKCZ,NRSN1,PROX1,RIMS3,GON4L,SPIRE1,PLPPR5,PMEPA1,HP1BP3,PARD6A,SV2A,ARNT2,KCNMA1,PEX5,KCNQ2,KIF2A,ATG16L1,GNE,JMJD1C,ZNF248,RBM12,RPRD1A,TMEM100" Drug CID000004450 nefopam Stitch 6.84E-06 2.22E-01 7.86E-04 8.61E-03 8 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,HRH3,ASIC3" Drug CID000031958 AC1L1MOZ Stitch 6.84E-06 2.22E-01 7.86E-04 8.61E-03 8 27 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,NKX6-2,ASIC3" Drug 6825_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.27E-06 2.36E-01 8.31E-04 9.12E-03 22 190 "ACTN2,NDRG2,FGF1,ASIC4,SLC6A9,PDE8B,FYN,ZCCHC24,SPART,ALDH1L1,RND1,ACSBG1,GNG3,WSCD1,CCKBR,SULT4A1,PLCH2,MAPK10,RAD52,PARP11,ATN1,TTLL7" Drug CID000003100 diphenhydramine Stitch 7.33E-06 2.38E-01 8.35E-04 9.16E-03 13 75 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ATM,SCN3B,AZIN2,HRH3,NTSR2,ASIC3,CHRM1,KCNJ4" Drug 4665_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ABAT,TUBB4A,TESK2,TAGLN3,BRINP2,FYN,TNIK,RGL1,RND1,VAMP1,USP2,PCDH9,DNAJC12,KIAA0513,RIMS3,SYTL2,DNAJC6,PLPPR4,SRGAP3,EFNA3" Drug 4710_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ADD3,TUBB4A,SORBS1,SYBU,CCDC88A,FYN,TNIK,ZCCHC24,RGL1,RND1,ACSBG1,GLS,SERPINE2,PIK3CD,DNAJC12,DNAJC6,TTLL7,EFNA3,VWA5A,RASGRP2" Drug 3312_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "TUBB4A,HPCAL4,PPM1E,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug 5209_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.97E-06 2.59E-01 8.96E-04 9.83E-03 21 177 "DPF1,ADD3,TUBB4A,SEMA6A,SORBS1,ASPH,FYN,TNIK,ZCCHC24,RGL1,ACSBG1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,TMCC2,EFNA3,RASGRP2" Drug ctd:D012834 Silver CTD 8.38E-06 2.72E-01 9.39E-04 1.03E-02 116 1958 "MAG,RABEPK,TTYH1,EPS8,ABAT,RIMKLA,MAPT,RCSD1,PAQR6,EXTL1,EYA1,MRVI1,ADAR,DSCAML1,WAC,ADORA3,NLGN4X,FCGR1A,AGT,SCN3A,SEMA6A,BCAR3,TRIM46,SELL,ANK2,BCAS1,SHTN1,USP16,URGCP,MADD,MSRA,PKNOX2,ARHGAP5,SLC8A2,MT3,SHANK2,SCMH1,ASCL1,SNAP25,ATP1A2,FYN,SOX1,MYT1L,ENKUR,NPAS3,BCL2L2,GFRA1,RGL1,RND1,ACSBG1,ABCC8,GLS,ADGRL3,WWC1,CACNA1A,GPM6B,TCF7L2,ZEB1,TCF12,NRGN,PTBP2,TMEM151B,PSD3,GRIA2,ADAMTS8,VWCE,TF,TMEM25,P2RX7,AIFM1,PAX6,TNR,HRH3,PDE1A,PDE1C,PDE2A,PDE4B,SCRG1,JAM2,NRXN2,SEMA5B,CP,POU3F2,TENM4,NKAIN4,VCAN,PRKCZ,CTNND1,MAPK8,ACY3,DPYSL5,PLPPR5,DNAJC6,ITGAV,PMEPA1,PTHLH,RGMA,PTPRE,PARD6A,SRGAP3,OLIG1,RAB5B,PID1,DNM2,SLC25A18,RASGRF1,RTN4,SLC6A15,CAMK1G,USH1C,RFX4,CACNG7,PIANP,SH3GLB1,PRRT4,RCAN2" Drug CID000446744 AC1L9K1W Stitch 8.44E-06 2.74E-01 9.41E-04 1.03E-02 10 45 "MAG,MBP,MOBP,MOG,FOLH1,NASP,GPM6B,OMG,POU3F4,L1CAM" Drug ctd:D010278 Parathion CTD 9.24E-06 3.00E-01 1.03E-03 1.13E-02 59 822 "EPS8,RIMKLA,ACHE,CDHR1,MBP,ADCY2,ADD3,FABP7,SLC44A5,SEMA6A,AMPH,CDC42BPA,SH3GL2,SLITRK3,JAKMIP3,ZNF365,SLC8A3,MT3,SPHKAP,ASPH,PHYHIPL,CADM3,NCAM1,NELL1,ASTN2,GPM6A,NUCB1,GRIA4,GRIK3,GRIN1,GUCY1A2,TIE1,MAEL,PADI2,CDH8,LILRA4,TMEFF2,JAM2,GDAP1L1,PIK3CD,CRMP1,ATRNL1,CTNND2,MASP1,DPYSL5,SIRPA,PRDM2,PTPRO,SV2A,AK5,CALN1,RAP1GAP,RASGRF1,BEND5,RET,RFX4,SSPN,BSCL2,EPB41L1" Drug CID000003784 isradipine Stitch 9.42E-06 3.06E-01 1.04E-03 1.15E-02 15 100 "ASIC1,RYR1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,GAD2,CACNA1A,CACNA1E,CACNB2,ASIC3,KCNMA1,CACNG7" Drug 5903_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.50E-06 3.09E-01 1.05E-03 1.15E-02 21 179 "DPF1,ADD3,TUBB4A,SEMA6A,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,VAMP1,CDK5R2,ZEB1,PCDH9,PIK3CD,DNAJC12,MAPK8,DNAJC6,VWA5A" Drug CID000003413 forskolin from Coleus forskohlii Stitch 9.81E-06 3.19E-01 1.08E-03 1.18E-02 69 1014 "ASIC1,ACHE,ACLY,MBP,ADAR,ADARB2,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,TUBB4A,AGT,SCN3A,SCN4B,SCNN1D,FGF1,ACTL6B,ASIC4,FOXM1,SLC14A1,PDE8B,SCN3B,CPLX2,GFAP,SYT4,GNAS,NODAL,NPPA,CACNB2,PRLHR,AZIN2,NUMA1,GRIA1,GRM3,PTPN5,LEFTY2,USP2,GUCY1A2,ZFP91,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PDYN,CHGA,ASIC3,CHRM1,CHRNB2,PIK3CD,HPR,P2RY12,PTPA,PRKACB,CALY,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,TUBB2B,PTCH1,PTHLH,RAP1GAP,RET,RGS7,RGS10" Drug CID000024766 chondroitin sulfate Stitch 9.83E-06 3.19E-01 1.08E-03 1.18E-02 36 413 "MAG,F3,FABP7,FGF1,MOBP,MOG,SELL,BCAN,NLGN1,CSPG5,B3GAT1,B4GALNT1,NCAM1,GFAP,CNTN2,NEU4,OMG,TGFBR3,TNR,HMGB1,SERPINE2,SEMA5B,PLXNB3,CNTN1,COL9A2,ATCAY,VCAN,NCAN,SDC3,ARHGEF4,ITIH2,PTPRZ1,NTM,RTN4,L1CAM,OLIG2" Drug 2546_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "APC2,CEND1,EYA1,KIAA1109,CDC42BPA,ANK3,SORBS1,ATP1A3,PALLD,GNG4,GRIK2,SPX,KCNK10,PADI2,TNS1,NRXN2,RGS6,DZIP3,PRKCG,ARHGEF4,KCNJ10,TMCC2" Drug 4082_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "DPF1,ACTN2,ADORA1,PLA2G6,MOBP,PKP4,SLC14A1,SLCO1A2,TNIK,ADGRB2,GRM3,TNS1,PCDH9,PDE3B,CADM1,CNTN1,IFFO1,ARHGEF4,JAKMIP2,RABGAP1L,CRTAC1,RET" Drug 5077_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-05 3.30E-01 1.10E-03 1.21E-02 22 194 "ACHE,RTN1,FOXRED2,PLA2G6,GAS7,SLN,ASTN1,PHLDB1,NEUROD1,SLCO1C1,ADGRL3,ATF7,NUMA1,CDH8,CALY,CTNND2,PROX1,MASP1,ITIH2,KCND3,RGS7,RASGRP2" Drug ctd:D009020 Morphine CTD 1.05E-05 3.41E-01 1.14E-03 1.25E-02 38 448 "MAPT,SYT9,DSCAML1,ADORA1,TUBB4A,AGT,ASIC4,SELL,DOCK10,NTNG1,BCAS1,AQP4,RPH3A,ADGRA1,GAD2,ARPP21,NCAM1,GFAP,PHLDB1,GNAS,CAMK2A,GRIA1,GRIA2,GRIA4,GRIN1,GPR88,CCKBR,PDYN,HPCA,OPALIN,CCDC136,RGS6,CMTM5,PRKCG,IGSF1,AK5,SLC17A6,ST8SIA3" Drug CID000002821 CNQX Stitch 1.05E-05 3.42E-01 1.14E-03 1.25E-02 17 126 "SLC8A2,B3GAT1,SOX10,GAD2,CACNA1A,CACNB2,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,NTSR2,CHRM1,PTCH1" Drug CID000656979 O-Ln Stitch 1.07E-05 3.46E-01 1.15E-03 1.26E-02 11 56 "MAG,MBP,ERMN,MOG,GFAP,GFRA1,TJP1,ZFP91,PTPA,RBPJ,RET" Drug CID000447081 1m5b Stitch 1.08E-05 3.52E-01 1.16E-03 1.27E-02 5 9 "GRIA1,GRIA2,GRIA4,GRIK2,GRM3" Drug CID000100099 gamma-Glu-Gly Stitch 1.09E-05 3.53E-01 1.16E-03 1.27E-02 9 37 "GFAP,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,PDYN,GOPC" Drug ctd:D007608 Kainic Acid CTD 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "SFPQ,SLC1A2,SLC8A3,MT3,GAD2,NCAM1,GFAP,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,AIFM1,CDC42,PDYN,HPCA,CNRIP1,KCNQ2,LMO1,EN2" Drug 3366_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "MDM4,FOXRED2,KIAA1109,FOXG1,PDE8B,WDTC1,SOX10,LMO3,PHLDB1,OMG,NEURL1,CDH8,LILRA4,PDE4B,CHRNB2,POU3F2,SNCAIP,VCAN,MAPK8,PLPPR1,RAB3IL1,NUP214" Drug 3620_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "MAPT,FGF1,ASIC4,RASA3,SLC6A9,SNAP25,TNIK,NMNAT2,CPLX2,ALDH1L1,FGF17,VAMP1,BRSK2,USP2,POU3F4,PTAFR,SMG7,TMCC2,RAD52,DPP6,LMO1,VWA5A" Drug 3212_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.10E-05 3.59E-01 1.16E-03 1.28E-02 22 195 "ARID1A,NDRG2,KIAA1109,ANK1,SLC2A5,PKNOX2,TAGLN3,ATP1A3,EMC1,ACSBG1,POPDC3,BTRC,WSCD1,CAMK2G,GUCY1A2,KIAA1549L,CHD5,ARHGEF4,NOS1AP,RIMS3,KCNK1,EFNA3" Drug 1535_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ADD3,TUBB4A,PPM1E,SYBU,ZNF365,FYN,ZCCHC24,RGL1,RND1,ACSBG1,VAMP1,ZEB1,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug 5987_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "DPF1,ADD3,TUBB4A,SORBS1,SYBU,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,EFNA3,VWA5A" Drug CID000006468 phencyclidine Stitch 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ACHE,FOLH1,SLC1A2,SLC14A1,DNER,NDUFA5,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,DAAM2,CHRNB2,HNRNPK,CRMP1,KCNT2,KCNA1,SLC25A18" Drug 6193_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.13E-05 3.67E-01 1.18E-03 1.29E-02 21 181 "ADD3,PPM1E,PALLD,ZCCHC24,ZSWIM8,NCAM1,RGL1,RND1,GPR19,PCDH9,RBFOX2,SERPINE2,NMT2,FEZ1,DZIP3,KIAA0513,RIMS3,DNAJC6,PARD6A,TMEM255A,EFNA3" Drug CID000005202 serotonin Stitch 1.15E-05 3.73E-01 1.18E-03 1.29E-02 44 554 "ACHE,ADAR,ADCY2,AGT,ACTL6B,API5,SLC1A2,SLC1A6,SLC1A7,B3GAT1,SNAP25,ATM,ATP1A2,ATP1A3,SOX10,GAD2,NPAS3,GFAP,ADHFE1,NUCB1,GRIN1,GRM3,TF,PAH,HPS5,HRH3,PRMT8,PDYN,CHGA,CHRM1,CHRNB2,HPR,P2RY12,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,KCNA6,SLC17A6,SLC6A15,RGS7,GPR61,EN2" Drug 1642_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "EMID1,FOXRED2,FHL1,FOXG1,C1orf61,CDC42BPA,ZCCHC24,NDUFA5,INKA2,ROBO3,NRGN,HAP1,FADS2,SULT4A1,PPP2R5C,MAPK8,EDRF1,PEX5,DSCAM,DTNA,VWA5A,LRRC23" Drug 4746_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "DPF1,MOBP,FOXG1,AMPH,ANK1,GAS7,RPH3A,SLC2A5,MSR1,MYH7,GLS,GNG3,GRIN1,TGFBR3,KCNK10,PCDH8,TPM3,GPR37L1,ATRNL1,MAPK10,STMN4,KCNMA1" Drug 4524_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MAPT,ACHE,ADORA1,ANK2,RASA3,SLN,CCDC181,GNG4,BTRC,GPM6B,GPR19,NEURL1,PDE4B,VCAN,CTNND2,PTAFR,PLPPR1,PRDM2,MAGI2,KCND3,RABGAP1L,RGS7" Drug 4347_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "FHL1,GAS7,SLC2A5,TAGLN3,DLL3,KIF21B,GLS,MYRF,CDK5R2,PRUNE2,CCKBR,PAX6,HPSE2,KIAA1549L,SULT4A1,POU3F4,ARHGEF4,MAPK8,PTPRO,KCNMA1,ST8SIA3,RASGRP2" Drug 6363_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "DPF1,ADCY2,C1orf61,ANK1,DOCK10,APC,SORBS1,RPH3A,PDE8B,MYBPC1,SOX10,PSD3,CELF3,PTGDR2,CA14,PIK3CD,SULT4A1,CNTN1,TENM4,RIMS3,PTAFR,PTCH1" Drug 425_DN staurosporine; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MAPT,NDRG2,GRAMD1B,PPM1E,ALDH4A1,WDTC1,NMNAT2,HAP1,HPS5,TMPRSS5,CHRM4,CCSER2,VAV2,NSD2,KIAA0513,SYTL2,DLG3,DSCAM,CAMK1G,VWA5A,EPB41L1,EPB41L2" Drug 4423_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "ARID1A,PLA2G6,FHL1,GAS7,RPH3A,PKNOX2,WDTC1,CADM3,EMC1,ALDH1L1,NEUROD1,AJAP1,GNAS,SERPINE2,FADS2,CNTN1,MICAL1,RIMS3,SYNC,RABGAP1L,ATN1,EN2" Drug 1546_UP Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "MBP,CEND1,NDRG2,ADORA1,C1orf61,ITSN1,BCAN,GJB1,CACNA1A,NPPA,NRGN,OMG,LILRA4,DUSP26,CAMKV,COL9A2,PRRX1,PACSIN1,TMCC2,CAMK1G,NUP214,ARHGEF10L" Drug 4370_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "FABP7,AGT,FHL1,CDC42BPA,APC,GAS7,SLC1A7,SLC2A5,CSPG5,TAGLN3,AJAP1,GPM6B,GUCY1A2,P2RX7,SEZ6L,JAM2,PIK3CD,SULT4A1,RAD52,SSPN,LMO1,ELAVL3" Drug 5758_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-05 3.89E-01 1.18E-03 1.29E-02 22 196 "PRR5L,TUBB4A,HPCAL4,FOXG1,APBB1,ATP1A2,ATP2B2,AJAP1,VAMP1,SEMA4A,PRUNE2,CAMK2A,BRSK2,PLEKHB1,PRDM2,PTPRD,SV2A,RABGAP1L,DNAH9,PAK5,EFNA3,VWA5A" Drug CID000001370 1-BCP Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000107978 beta-N-oxalylaminoalanine Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000063114 AC1L1YEG Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000129091 5-h PCA Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID003038472 irampanel Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011334126 CHEBI:570577 Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000656707 LY395153 Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID003005587 thioformamide Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "F3,ABCC8,PMP2,ABCC9" Drug CID000065740 Chicago acid Stitch 1.20E-05 3.90E-01 1.18E-03 1.29E-02 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug 5017_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-05 3.99E-01 1.20E-03 1.31E-02 21 182 "ADD3,TUBB4A,SORBS1,CCDC88A,DNAH17,FYN,TNIK,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,NRGN,TGFBR3,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,TMCC2,EFNA3" Drug CID000005673 AC1Q646P Stitch 1.27E-05 4.14E-01 1.20E-03 1.31E-02 10 47 "PDE8B,PDE1A,PDE1C,PDE2A,PDE4B,POU3F2,KCNA1,KCNA2,KCNA6,KCNQ2" Drug 5960_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "PLA2G6,MOBP,SELL,AMPH,SLC2A5,DNAH17,ALDH4A1,ADGRB2,NEUROD1,VAMP1,GNG4,CDK5R2,ZEB1,PADI2,PTGDR2,POU3F4,MAPK8,AK5,RAP1GAP,RGS10,LPAR6,ROM1" Drug 3063_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CHST15,SEMA6A,AQP4,SLN,CCDC181,PALLD,DKK3,ARPP21,NAP1L2,NPPA,ATP13A2,TGFBR3,CDH10,CHI3L2,JAM2,ZFYVE9,FLRT1,RGS6,KCNC1,RASGRF1,RGS7,EPB41" Drug 4653_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "TTYH1,ABAT,MOBP,C1orf61,SELL,APC,AQP4,SNAP25,SOX10,GPM6A,GRIN1,USP2,CDH10,CHI3L2,HPCA,SLC22A6,NRXN2,RGS6,KCND3,AK5,ARNT2,VWA5A" Drug 6011_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MAPT,ADORA1,MOBP,AMPH,RASA3,RPH3A,BRINP2,WDTC1,ZCCHC24,NCAM1,GFAP,CDH10,HRH3,PDE3B,CHRNB2,CAMKV,PTAFR,ELMO1,KCND3,ATN1,CAMK1G,ST8SIA3" Drug 2186_UP Evoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "PLA2G6,MOBP,ANK3,SLC1A7,SHANK2,SOX10,FGF17,NEUROD1,VAMP1,CAMK2A,NEURL1,PTGDR2,GPR37L1,ASIC3,DUSP26,FLRT1,PARD6A,KCND3,PEX5,PAK5,ABCC9,CAMK1G" Drug 6367_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "KIAA1109,FHL1,C1orf61,ANK1,APC,NTNG1,RPH3A,SLC2A5,SHANK2,DNAH17,NPAS3,PHLDB1,PSD3,TNS1,HRH3,PIK3CD,SULT4A1,VAV2,CALY,MAPK8,MASP1,OLIG2" Drug 2674_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "FABP7,FHL1,ALDH4A1,B3GALT2,CADM3,GAD2,NCAM1,MYRF,TGFBR3,DAAM2,PCDH9,HPSE2,NRXN2,DZIP3,MAPK10,PROX1,RIMS3,DNAJC6,KCND3,ABI2,LPAR6,LRRC23" Drug 4737_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CEND1,KIAA1109,PLA2G6,MOBP,CDC42BPA,ASCL1,ATP1A2,SPART,ALDH1L1,NEUROD1,AJAP1,ACSBG1,GNG3,OPCML,PDE4B,CHRNB2,VAV2,RIMS3,PTHLH,KCND3,ATN1,VWA5A" Drug 3678_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MAPT,ASTN1,SCN3B,ZSWIM8,NPAS3,ALDH1L1,INKA2,RND1,GPM6A,GRIK2,NEURL1,TNS1,PTGDR2,CHI3L2,FLRT1,CRMP1,EDRF1,TOX,RIMS3,RABGAP1L,ARNT2,DTNA" Drug 2324_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ADORA1,PLA2G6,FGR,CDC42BPA,APC,BCAN,SLC2A5,PKNOX2,SORCS3,ATP2B2,INKA2,POPDC3,PSD3,PTGDR2,ZMYND8,SCRG1,SNCAIP,MAPK8,KCND3,TMCC2,NUP214,RGR" Drug 3112_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "SYNDIG1,ACTN2,ARID1A,RYR1,FOXG1,NTNG1,SLC14A1,ALDH4A1,LMO3,BCL2L2,PRUNE2,GPM6A,MAGI1,TMPRSS5,CCSER2,VAV2,MASP1,RIMS3,PEX5,ATN1,SIDT2,LRRC23" Drug 3117_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ABAT,GRAMD1B,CDC42BPA,ANK3,GPR153,CCDC181,GAD2,RAP1GAP2,WWC1,GPM6A,CACNB2,GUCY1A2,PADI2,PDE1C,ARHGEF4,MAPK8,ECE2,SYNC,KCNMA1,KCNN3,PAK5,ROM1" Drug 3350_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "NDRG2,F3,KIAA1109,APBA2,GAS7,AQP4,SLC1A2,ASCL1,SLN,CPLX2,TLL2,KCNK10,DAAM2,PCDH9,CDH8,PDE3B,CHRNB2,PIK3CD,PACSIN1,KCNJ4,KCNMA1,RAB3IL1" Drug 3621_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "SYNDIG1,RYR1,AGT,RASA3,ASCL1,GAD2,ACSBG1,ROBO3,GPM6A,CRB1,KCNK10,PTGDR2,NCAN,PKN2,RIMS3,PARD6A,KCND3,SRGAP3,KCNK2,ATN1,RASGRF1,RASGRP2" Drug 2305_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "MDM4,NDRG2,CDC42BPA,SLC6A9,DNAH17,ASPH,SOX10,GFAP,KAZN,CAMK2G,CELF3,TNS1,SEZ6L,CHRNB2,SERPINE2,FADS2,PTAFR,RABGAP1L,RASGRF1,L1CAM,NUP214,SEC61A2" Drug 6054_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "DPF1,SYNDIG1,AGT,FGF1,FHL1,APBA2,SHANK2,ATP2B2,ZCCHC24,NEUROD1,NPPA,DAAM2,HPSE2,RGS6,NCAN,SDC3,KCND3,KCNJ4,PARP11,DPP6,ST8SIA3,TTLL7" Drug 5045_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "CEND1,RYR1,PDE8B,CADM3,GAD2,PHLDB1,BTRC,ADGRL3,PRUNE2,CRB1,TPM3,PDE3B,PDE4B,SPATA6,FEZ1,MAPK10,PROX1,ITIH2,RAD52,DTNA,ST8SIA3,RGS10" Drug 2351_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.30E-05 4.22E-01 1.20E-03 1.31E-02 22 197 "ACTN2,FOXRED2,SCN3A,RASA3,NLGN1,ZNF365,ALDH4A1,ATP1A3,ARPP21,NDUFA5,VAMP1,GNG3,CACNA1A,REPS2,PDE1C,CRMP1,SYTL2,PTAFR,SV2A,PEX5,SSPN,RASGRP2" Drug 6179_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.34E-05 4.35E-01 1.22E-03 1.34E-02 21 183 "ADD3,TUBB4A,TESK2,ALDH4A1,PALLD,ZSWIM8,NCAM1,RGL1,RND1,GLS,CAMSAP2,ATP13A2,INA,PADI2,PCDH9,KIAA0513,RIMS3,DNAJC6,PARD6A,TMEM255A,EFNA3" Drug 6192_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "APC2,ARID1A,RYR1,ADORA1,FHL1,HPCAL4,ANK3,SHANK2,ALDH4A1,GFRA1,INKA2,PHLDB1,DAAM2,TNS1,PTGDR2,TMPRSS5,CHI3L2,CHRM4,CTNND2,ATN1,ABCC9,ROM1" Drug 6139_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,RYR1,CDC42BPA,ANK2,GPR153,SNAP25,NEUROD1,SLCO1C1,WWC1,WSCD1,GRM3,ATP13A2,CELF3,MAGI1,CHRM4,NECAB2,POU3F2,PLPPR4,SV2A,ABCC9,RGR,EFNA3" Drug 6611_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,FOXG1,SELL,APC,GAS7,SHANK2,NPAS3,SPART,ALDH1L1,RND1,GNG4,BTRC,OMG,CDH8,ARHGAP22,SPATA6,FEZ1,VCAN,RIMS3,ARNT2,DLG3,VWA5A" Drug 5797_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,ACTN2,ANK2,NTNG1,SLN,TNIK,NCAM1,MYRF,BTRC,NPPA,DAAM2,CDH8,LILRA4,PDE3B,ZMYND8,FAM131B,MASP1,RABGAP1L,NAV2,SLC17A6,NUP214,ELAVL3" Drug 5207_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,APC,BCAN,AQP4,SNAP25,SOX10,BCL2L2,RGL1,PHLDB1,OPCML,USP2,GUCY1A1,SDC3,MAPK8,PTHLH,PARD6A,RAB3IL1,ATN1,SSPN,SIDT2,ELAVL3,EN2" Drug 2293_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "AMPH,GAS7,BCAN,DNAH17,TAGLN3,ATP2B2,TNIK,NMNAT2,POPDC3,BTRC,WSCD1,GPM6A,CCKBR,PTGDR2,TPM3,PDE4B,FADS2,SF1,NCAN,KCND3,SLC17A6,EN2" Drug 6255_UP Spironolactone [52-01-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAG,CDHR1,CDC42BPA,ANK3,APC,SLC6A9,PDE8B,SOX10,EMC1,NDUFA5,SEMA4A,BTRC,CAMK2G,OMG,GUCY1A2,SEZ6L,HPSE2,MAPK8,SYNC,JAKMIP2,DTNA,EFNA3" Drug 6363_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,EXTL1,ARID1A,HPCAL4,ANK2,APBA2,B3GALT2,EMC1,ACSBG1,POPDC3,GNG3,GPM6B,NPPA,ZEB1,HAP1,USP2,PIK3CD,ETNPPL,EDRF1,PROX1,STMN4,KCNA2" Drug 5904_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "KCNIP2,ADORA1,FGR,SLC1A7,CADM3,COLGALT2,PHLDB1,RND1,TMEM151B,CCKBR,USP2,INA,KCNK10,SEZ6L,TMPRSS5,SULT4A1,VAV2,MAPK10,RIMS3,PLPPR1,ITIH2,RASGRP2" Drug 4764_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ASIC1,EMID1,FHL1,C1orf61,PDE8B,CSPG5,KIF21B,POPDC3,GNG3,TCF7L2,DAAM2,CDC42,CHI3L2,ASIC3,VAV2,CRMP1,VCAN,MAPK8,SYNC,TMCC2,KCNMA1,NKAIN1" Drug 2811_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACTN2,RYR1,FOXG1,RASA3,NLGN1,SLC1A2,SLC6A9,CADM3,EMC1,RND1,GLS,SEMA4A,CACNB2,ZEB1,CAMK2G,KCNK10,CDC42,ASIC3,PTPRO,RAB3IL1,DTNA,VWA5A" Drug 4218_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACHE,RASA3,AQP4,SLC1A6,ASCL1,ATP1A2,NCAM1,INKA2,VAMP1,ADAMTS8,CRB1,USP2,TLL2,SEZ6L,PRMT8,GPR37L1,IGSF1,MAPK8,KCNJ9,RASGRF1,EPB41,RASGRP2" Drug 3824_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACTN2,RTN1,FOXG1,RND1,NEURL1,PADI2,PDE3B,CHI3L2,MED1,RGS6,IGSF1,PROX1,MAGI2,SMG7,SRGAP3,DLG2,RAB3IL1,ATN1,RASGRF1,ABCC9,RET,VWA5A" Drug 5763_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "SYNDIG1,ADCYAP1R1,TUBB4A,FOXG1,C1orf61,APBB1,BCAS1,TAGLN3,BRINP2,SORCS3,SCN3B,NDUFA5,P2RX7,DAAM2,NRXN2,MICAL2,ARHGEF4,MAPK10,ITIH2,DTNA,ABCC9,VWA5A" Drug 4261_UP Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ACHE,NDRG2,ANK1,B3GALT2,MYH7,NEUROD1,SLCO1C1,VAMP1,NUMA1,SPX,LILRA4,HPSE2,HPCA,ARHGEF4,PRDM2,KCNC1,KCND3,KCNH1,NTM,KCNJ9,ATN1,ABCC9" Drug 5615_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAG,KIAA1109,ASIC4,ITSN1,GAS7,ZSWIM8,PHLDB1,RND1,GLS,PRUNE2,GPM6A,HAP1,OMG,PTGDR2,CRMP1,VCAN,MAPK8,MAPK10,NOS1AP,MASP1,KCNA2,RABGAP1L" Drug 3342_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,CDHR1,KCNIP2,SEMA6A,FHL1,MOBP,GAS7,BCO1,MSR1,TAGLN3,BRINP2,SORCS3,GNAS,HAP1,PDE4B,CHI3L2,ZFYVE9,VAV2,VCAN,RIMS3,PTHLH,ST8SIA3" Drug 2557_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MAPT,ACTN2,MOBP,RASA3,PKP4,TAGLN3,TNIK,RAP1GAP2,MYRF,PRUNE2,GPM6B,GPR19,NUMA1,PSD3,ZFYVE9,CNTN1,PKN2,EDRF1,SLC17A6,CAMK1G,RET,RASGRP2" Drug 2714_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "MBP,ACTN2,PLA2G6,CDC42BPA,GAS7,ZNF365,TNIK,FGF17,BTRC,KLHL4,TGFBR3,PDE1C,PRMT8,TMPRSS5,VAV2,BEST1,KLK6,KIAA0513,CAB39L,SUSD4,EFNA3,RASGRP2" Drug 1499_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "EMID1,ACTN2,NDRG2,F3,APC,BCAS1,TAGLN3,ALDH4A1,SOX10,ADGRB2,ASTN2,BTRC,CAMK2G,NUMA1,PRMT8,CCSER2,MICAL1,SDC3,TMCC2,DTNA,ROM1,LRRC23" Drug 3371_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.41E-05 4.57E-01 1.22E-03 1.34E-02 22 198 "ASIC1,APC2,ADORA3,PLA2G6,FOXG1,SORBS1,SLCO1A2,TAGLN3,SLN,SORCS3,SOX10,GPM6A,ATF7,PIK3CD,SULT4A1,PLCH2,PROX1,PTAFR,ITIH2,KCND3,SRGAP3,SLC6A15" Drug ctd:C005460 uranyl acetate CTD 1.42E-05 4.61E-01 1.23E-03 1.35E-02 26 258 "ACHE,NDRG2,ADAR,SLC44A5,APBB1,APC,NSG2,KIF1B,ABCC8,KAZN,TNFRSF1B,PDE1A,HMGB1,CHRM1,CHRNB2,C11orf49,MFSD4A,CRLS1,SDC3,PUM1,DPYSL5,TOMM20,CSDE1,PLEKHB2,DTNA,BAALC" Drug CID000002482 butamben Stitch 1.43E-05 4.64E-01 1.23E-03 1.35E-02 6 15 "CACNA1A,CACNA1E,KCNA1,KCNC1,KCND3,L1CAM" Drug CID000031657 Vydate Stitch 1.43E-05 4.64E-01 1.23E-03 1.35E-02 6 15 "ACHE,FOLH1,SHANK2,DDR1,PTPN5,HPR" Drug CID000002818 clozapine Stitch 1.47E-05 4.77E-01 1.24E-03 1.36E-02 27 274 "SERPINA3,ADAR,SLC1A2,NRG3,NPAS3,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRIN1,GRM3,AIFM1,HRH3,PDE4B,NTSR2,CHGA,CHRM1,CHRNB2,CALY,PRKCG,PKN2,PRKCZ,SLC17A6,DTNA,SSPN,OLIG2" Drug 5079_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ASIC1,ACTN2,MDM4,PLA2G6,BBOX1,ANK1,SLN,KIF21B,PHLDB1,NEUROD1,ADGRL3,PRUNE2,USP2,SEZ6L,LILRA4,MAGI1,CRMP1,VCAN,PROX1,PID1,DSCAM,RGS10" Drug 2737_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FHL1,BBOX1,CDC42BPA,ANK3,NLGN1,SLC6A9,ATP1A3,PALLD,ACSBG1,GRIN1,GUCY1A1,SEZ6L,ARHGEF4,PHYHIP,STMN4,KCNC1,KCND3,SRGAP3,FAM13C,ST8SIA3,RGR,EPB41" Drug 6364_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,EXTL1,ARID1A,HPCAL4,MOBP,SLC1A7,ASPH,B3GALT2,CADM3,EMC1,CPLX2,ADGRB2,ACSBG1,MYRF,GPM6B,PROX1,PTHLH,STMN4,KCNA2,ATN1,RGS10,ELAVL4" Drug 4501_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "DPF1,EMID1,ADCY2,RYR1,PLA2G6,C1orf61,TRIM46,BCAS1,SLC1A7,SLC2A5,PKNOX2,SEMA4A,GNG3,KLHL4,NEURL1,TNS1,CDH8,PDE4B,VAV2,MAGI2,RABGAP1L,ST8SIA3" Drug 5542_DN Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "SERPINA3,APC,BCAS1,SLC1A7,PDE8B,ZCCHC24,NUCB1,ATP13A2,TGFBR3,TPD52,PDE3B,PTPA,CTNND2,SMG7,DLG3,RAD52,RGS10,EFNA3,ABI2,ROM1,EPB41L1,EPB41L2" Drug 2285_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "CDC42BPA,SLC2A5,BRINP2,ATP2B2,SOX10,NDUFA5,GPR162,ATF7,NPPA,PSD3,OMG,USP2,SEZ6L,VAV2,VCAN,MAPK8,NOS1AP,PTAFR,KCNC1,KCNMA1,ATN1,CRTAC1" Drug 4220_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FOXRED2,C1orf61,RASA3,PKNOX2,ASCL1,ATP1A2,GJB1,USP2,P2RX7,TNS1,PTGDR2,GPR37L1,NRXN2,CABP1,RGS6,NOS1AP,PRDM2,KCNA2,KCNH1,ABCC9,ST8SIA3,EPB41" Drug 4068_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAG,ACTN2,RYR1,HPCAL4,MOBP,SORBS1,SLCO1A2,NFASC,AJAP1,VAMP1,CDK5R2,OLR1,PDE2A,TMPRSS5,NRXN2,PIK3CD,SULT4A1,CHD5,KCNJ4,KCNJ9,DSCAM,USH1C" Drug 3777_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "CEND1,SELL,DOCK10,BCAN,SLC14A1,PDE8B,SCN3B,RND1,SLCO1C1,GNG4,GRIK2,TPM3,HPSE2,ZFYVE9,KIAA1549L,MAPK10,TOX,ATN1,DSCAM,DTNA,RGS10,ELAVL3" Drug 2320_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MOBP,CDC42BPA,BCAN,SLC1A7,BCO1,SLCO1A2,B3GAT1,ZSWIM8,GLS,CACNA1A,NPPA,CHRNB2,POU3F4,VCAN,SDC3,PTCH1,PTHLH,ITIH2,KCND3,TMCC2,DTNA,RAVER2" Drug 3883_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,SEMA6A,ANK1,AQP4,SLC6A9,ASCL1,ATM,ZSWIM8,MYH7,GLS,ROBO3,PRUNE2,CHI3L2,ZFYVE9,NECAB2,SNCAIP,PTAFR,PTHLH,ITIH2,CNIH3,L1CAM,RASGRP2" Drug 5078_UP Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EMID1,MOBP,ANK1,NLGN1,AQP4,CCDC181,VAMP1,GNG3,GRIN1,ADAMTS8,INA,PDE4B,JAM2,ST8SIA5,NOS1AP,TOX,PRDM2,KCNA2,KCNC1,RAD52,SLC6A15,VWA5A" Drug 3707_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EYA1,FABP7,ANK1,NLGN1,RPH3A,SLC1A7,DKK3,LMO3,ACSBG1,KAZN,GPR19,PADI2,TNS1,TPM3,PRMT8,CA14,IGSF1,NOS1AP,PROX1,MAGI2,DTNA,ST8SIA3" Drug 4201_UP Atovaquone [95233-18-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "NDRG2,HPCAL4,PKP4,SNAP25,CADM3,BTRC,HAP1,OLR1,OMG,PTGDR2,MAGI1,CAMKV,SPATA6,PLCH2,PTAFR,PLPPR1,AK5,ARNT2,SLC17A6,DTNA,VWA5A,ROM1" Drug 6713_UP Monobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "EMID1,MOBP,FOXG1,PKP4,APC,NTNG1,RPH3A,ATP1A3,ATP2B2,SOX10,NEUROD1,CACNA1A,GPM6A,GRIK3,PC,FEZ1,CTNND2,KCND3,SRGAP3,CRTAC1,VWA5A,EPB41" Drug 3762_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "APC2,FGF1,PKP4,SLC1A2,MSR1,TAGLN3,ATP1A2,RND1,ACSBG1,VAMP1,OMG,INA,PDE2A,JAM2,SPATA6,POU3F4,MASP1,PTPRO,SRGAP3,ARNT2,NKAIN1,RET" Drug 5408_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ARID1A,ADORA1,MOBP,FOXG1,GAS7,BCAN,SLC2A5,PHLDB1,NEUROD1,RND1,GPM6A,CAMK2G,OMG,OPCML,CDH10,PDE3B,SERPINE2,MAPK8,SYNC,PTHLH,KCNC1,KCND3" Drug 3674_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,ADCY2,C1orf61,SELL,RASA3,NTNG1,MSR1,SLCO1A2,BRINP2,ALDH4A1,SNAP25,ADGRB2,VAMP1,MYRF,GRIN1,GRM3,NEURL1,PDE3B,DUSP26,SULT4A1,SNCAIP,ELAVL4" Drug 6524_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "MAPT,ACTN2,TUBB4A,FHL1,GAS7,URGCP,SLN,MYH7,COLGALT2,ALDH1L1,NDUFA5,FGF17,CACNB2,CAMK2G,PSD3,USP2,HRH3,ZMYND8,PLEKHB1,IFFO1,DTNA,EFNA3" Drug 6394_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "FOXG1,ANK1,DOCK10,SORBS1,MSR1,ASCL1,SLCO1A2,ATP2B2,KIF21B,COLGALT2,GFAP,WSCD1,GDAP1L1,MICAL2,PLCH2,DNAJC6,ITIH2,ELMO1,PRDM2,KCNMA1,ATN1,CAMK1G" Drug 2689_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ABAT,MOBP,C1orf61,ANK3,RPH3A,SNAP25,ATP1A3,CADM3,BRSK2,GRIK2,ADAMTS8,CRB1,NEURL1,CDH10,GPR37L1,PHKG1,NMT2,FLRT1,CABP1,STMN4,RASGRF1,ST8SIA3" Drug CID000023982 gadolinium Stitch 1.52E-05 4.95E-01 1.24E-03 1.36E-02 22 199 "ASIC1,MBP,ADGRV1,RYR1,ASIC4,ST8SIA1,MTR,B4GALNT1,GFAP,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRM3,AIFM1,KCNK10,TNFRSF1B,KCNK2,CACNG7" Drug CID005282252 NS 102 Stitch 1.55E-05 5.03E-01 1.25E-03 1.38E-02 7 22 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000121892 retigabine Stitch 1.55E-05 5.04E-01 1.25E-03 1.38E-02 10 48 "ABAT,ANK3,ARFGAP1,CHRNB2,KCNA1,KCNA2,KCNC1,SV2A,NTM,KCNQ2" Drug CID000000191 arabinosyladenine Stitch 1.59E-05 5.15E-01 1.28E-03 1.40E-02 55 762 "ADAR,F3,ADARB2,ADCY2,RYR1,ADORA1,ADORA3,ACTL6B,APC,MADD,PDE8B,SLCO1A2,ATP1A2,ATP1A3,ATP2B2,MYBPC1,AHCYL1,GART,ABCC8,GNAS,CACNA1A,GPM6A,CACNA1E,NPPA,CACNB2,GRIA2,GRIA4,GRIK2,GRM3,GUCY1A2,P2RX7,GUCY1A1,RBFOX2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,PIK3CD,UBTF,P2RY12,ATCAY,PTPA,PRKACB,PRKCG,PKN2,PRKCZ,PLPPR5,AK5,KCNMA1,PYGM,DPP6,ABCC9,LPAR6" Drug 2558_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "ACTN2,CDC42BPA,RASA3,PKP4,SLC6A9,ARHGAP5,ASCL1,ASPH,SPART,INA,PTGDR2,PDE3B,CHRNB2,ZFYVE9,FLRT1,VCAN,PRKCZ,CNIH3,TMCC2,NAV2,DTNA,LPAR6" Drug 4995_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "FHL1,ANK3,PDE8B,ALDH4A1,WDTC1,INKA2,GLS,GNAS,GPM6B,CCKBR,KCNK10,CHRNB2,CAMKV,VAV2,CNTN1,ARHGEF4,MAPK8,SV2A,ATN1,TTLL7,VWA5A,LRRC23" Drug 4242_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "RTN1,SELL,PKP4,APBB1,PKNOX2,ATP2B2,TNIK,RND1,AJAP1,CACNB2,HAP1,OLR1,PDE3B,SLC22A6,SULT4A1,NCAN,PARD6A,KCND3,DNAH9,RAD52,DTNA,RAVER2" Drug 2409_UP Bumetanide [28395-03-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-05 5.36E-01 1.32E-03 1.44E-02 22 200 "FOXG1,ANK3,DOCK10,APC,SORBS1,TAGLN3,SNAP25,ZCCHC24,CADM3,RAP1GAP2,GLS,CACNA1A,GRIK2,TGFBR3,REPS2,TNS1,SERPINE2,CAMKV,MAPK8,PTPRD,DSCAM,FAM13C" Drug CID000003331 felbamate Stitch 1.84E-05 5.98E-01 1.47E-03 1.61E-02 12 70 "ABAT,ADGRV1,GAD2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,PTCH1" Drug CID000001779 "5,7-dichlorokynurenic acid" Stitch 1.88E-05 6.11E-01 1.49E-03 1.64E-02 10 49 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TPM3,PTPA,SLC25A18" Drug 5594_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.91E-05 6.21E-01 1.52E-03 1.66E-02 20 173 "ADD3,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,SRGAP3,VWA5A" Drug CID000120739 G 3012 Stitch 1.96E-05 6.36E-01 1.55E-03 1.70E-02 17 132 "SEMA6A,SEMA6C,NTNG1,LRRC4C,SLC14A1,SLIT1,FYN,NKX2-2,SEMA4A,ROBO3,UNC5D,CNTN2,HMGB1,RGMA,RTN4,L1CAM,EFNA3" Drug 6609_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.08E-05 6.76E-01 1.64E-03 1.80E-02 20 174 "ABAT,CEND1,SORBS1,ATP1A3,FYN,GAD2,RGL1,RND1,GLS,VAMP1,DNAJC12,VCAN,PROX1,KIAA0513,SYTL2,DNAJC6,PLPPR4,PID1,RGS7,EFNA3" Drug CID000131938 LY235959 Stitch 2.11E-05 6.86E-01 1.66E-03 1.82E-02 8 31 "FOXM1,SLC1A2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000005365 4-methylglutamic acid Stitch 2.11E-05 6.86E-01 1.66E-03 1.82E-02 8 31 "SLC1A2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000000764 guanine Stitch 2.14E-05 6.93E-01 1.67E-03 1.83E-02 62 903 "EPS8,RTKN,ADAR,ADARB2,ADCY2,ADORA1,ADORA3,TUBB4A,SELL,RASA3,PKP4,APC,MADD,PDE8B,ARFGAP1,NMNAT2,GART,RGL1,NEUROD1,RND1,GNAS,GNG3,GNG4,CACNA1E,DIRAS1,GRIA1,GRIA2,GRIA4,GRID1,RFFL,GRIK4,GRM3,CCKBR,P2RX7,CDC42,MAGI1,PDE2A,IGFN1,CHRM1,VAV2,PMP2,P2RY12,RGS6,PRKACB,CTNND1,MAPK8,MAPK10,MASP1,TUBB2B,PRTFDC1,RAB5B,RALGDS,ABI1,RASGRF1,GNE,USH1C,RGS7,ARHGEF10L,EEF1A2,LPAR6,BSCL2,RASGRP2" Drug 2904_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.19E-05 7.11E-01 1.71E-03 1.88E-02 21 189 "PRR5L,NDRG2,FHL1,ASRGL1,ARHGAP5,PALLD,TNIK,NCAM1,RGL1,CAMSAP2,ZEB1,GPR19,INA,PCDH9,FEZ1,RIMS3,DNAJC6,MAGI2,TMEM255A,TTLL7,SIDT2" Drug ctd:D008731 Methoxychlor CTD 2.20E-05 7.14E-01 1.71E-03 1.88E-02 43 551 "MAG,MBP,MEG3,AMPH,SFPQ,ITSN1,DGKZ,SLC1A2,SLC1A6,SLC8A2,ATP1A2,FYN,KIF1B,NFIA,SYT4,GNAS,CACNA1A,ACSL6,CACNB2,HAP1,GRIA2,GRIN1,GRM3,PTPN5,PDE2A,PDYN,CHGA,PHKG1,CP,MED1,SDC3,MAPK8,MAPK10,SIRPA,MAGI2,KCNA2,KCNA4,KCNC1,KCNMA1,DLG3,SLC17A6,DPP6,RALGDS" Drug 3746_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.26E-05 7.35E-01 1.75E-03 1.92E-02 20 175 "ABAT,MAPT,TUBB4A,FYN,TNIK,NFASC,RGL1,RND1,HAP1,USP2,PCDH9,PDE2A,PIK3CD,DNAJC12,RIMS3,SYTL2,DNAJC6,PLPPR4,EFNA3,VWA5A" Drug 4436_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.26E-05 7.35E-01 1.75E-03 1.92E-02 20 175 "ABAT,MAPT,BRINP2,FYN,RGL1,GLS,HAP1,USP2,PCDH9,CADM1,DNAJC12,KIAA0513,RIMS3,SYTL2,PTAFR,PTCH1,DNAJC6,JAKMIP2,PLPPR4,VWA5A" Drug CID000001271 L-CCG-I Stitch 2.27E-05 7.37E-01 1.75E-03 1.92E-02 10 50 "ADORA1,SLC1A2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,KCNMA1,SLC17A6" Drug ctd:C487081 belinostat CTD 2.29E-05 7.43E-01 1.77E-03 1.94E-02 50 679 "MAP6,IL17D,RTN1,CHST15,ELMOD1,SOX6,USP28,DOCK10,SESN3,SFMBT2,LRRC55,SCG3,SLIT1,ASTN1,SNAP25,TNIK,DNER,LMO3,COLGALT2,SMOC1,GFRA1,ADGRL3,ZEB1,AKNA,CCKBR,CRB1,SPX,PTPN5,PCDH8,LGI1,ADGRG1,CHGA,NLGN3,GDAP1L1,KIAA1549L,NRXN2,NEGR1,CNTN1,NCAN,PLD5,ARHGEF4,HES5,ANKS1B,MAGI2,OLFM3,RABGAP1L,ARNT2,SSPN,LPAR6,SEZ6" Drug ctd:C006703 benzo(b)fluoranthene CTD 2.30E-05 7.45E-01 1.77E-03 1.94E-02 95 1564 "SERPINA3,ZFYVE27,RIMKLA,EMID1,RCSD1,MEG3,ADGRV1,LDLRAD3,RTKN,MDM4,F3,PLEKHG5,ADCYAP1R1,ADD3,ERMN,ADORA3,FGF1,SEMA6A,GOLGA7B,HPCAL4,SELL,ANK3,ANXA7,MAGI3,ZNF365,RUFY2,MSR1,NSG2,CGREF1,ARFGAP1,ASPH,SLN,DDX25,PALLD,SCN3B,ADAM15,CPLX2,GPR162,INKA2,GJB1,RND1,SEPT3,KAZN,MMD2,PSRC1,TCF7L2,TCF12,NRDC,NRGN,HAP1,CAMK2G,TF,PTPN5,TMEM25,USP2,MFSD2A,P2RX7,TIE1,TNS1,PDE2A,CIART,ZMYND8,HMGB1,CA14,LRTM2,PFKFB3,MS4A7,TMEFF2,ARHGAP22,ANLN,CPT1C,CELF5,CP,FEZ2,MICAL2,OSBPL3,FMN2,MAPK10,NOS1AP,FGFR1OP2,TUBB2B,KCNH1,OLIG1,TMEM255A,FAM57B,RAP1GAP,SUSD4,FAM13C,TTLL7,SYT15,SSPN,PIANP,LPAR6,BSCL2,EPB41" Drug ctd:C076029 olanzapine CTD 2.45E-05 7.96E-01 1.88E-03 2.06E-02 16 121 "SERPINA3,AQP4,PDE8B,SNAP25,GAD2,CAMK2A,GRIA2,DCLK1,PDE1A,CHRM1,CP,NCAN,ITIH2,KCNA1,RTN4,RGS7" Drug 4565_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.46E-05 7.99E-01 1.88E-03 2.07E-02 20 176 "ABAT,TESK2,SH3GL2,SORBS1,TAGLN3,FYN,TNIK,ADGRB2,RGL1,RND1,GLS,HAP1,TGFBR3,USP2,REPS2,DNAJC12,KIAA0513,PTCH1,DNAJC6,PLPPR4" Drug CID000004587 AC1NFC6P Stitch 2.48E-05 8.07E-01 1.90E-03 2.08E-02 18 148 "MAG,MBP,MOBP,BCAN,MSRA,ASCL1,NCAM1,GFAP,FGF17,PCDHGA3,PAX6,TNR,CDH8,HEPACAM,PMP2,OLIG1,EN2,OLIG2" Drug 5917_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MDM4,RYR1,ADORA1,ZNF365,ALDH4A1,FYN,NMNAT2,EMC1,ATF7,GRM3,CDC42,CNTN1,ATRNL1,EDRF1,PTPRE,KCNJ4,TMCC2,NAV2,RAD52,EFNA3,VWA5A" Drug 2955_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "SYNDIG1,ADORA3,FGR,AMPH,CDC42BPA,NTNG1,BCAS1,GPR153,TAGLN3,NPAS3,ALDH1L1,PADI2,UBTF,NMT2,ST8SIA5,DZIP3,ZBTB16,SMG7,DLG3,SEC61A2,EFNA3" Drug 497_UP 2-propylpentanoic acid; Up 200; 1000uM; ssMCF7; HG-U133A Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MAPT,NDRG2,FHL1,PPM1E,SNAP25,FYN,ZCCHC24,NMNAT2,B4GALNT1,ADGRB2,SPART,WSCD1,NRGN,CAMK2A,ATP13A2,DNAJC12,MICAL1,ECE2,SUSD4,TTLL7,EFNA3" Drug 3058_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.57E-05 8.34E-01 1.94E-03 2.13E-02 21 191 "MAPT,APC2,ACTN2,WLS,NDRG2,SEMA6A,ASCL1,TNIK,RGL1,CAMSAP2,ATP13A2,REPS2,PCDH9,DZIP3,KIAA0513,RIMS3,DNAJC6,PTHLH,TMEM255A,RASGRF1,EPB41" Drug 4954_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.67E-05 8.68E-01 2.01E-03 2.21E-02 20 177 "ADD3,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,TGFBR3,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,SRGAP3,TMCC2,TTLL7,EFNA3,RASGRP2" Drug 5745_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.67E-05 8.68E-01 2.01E-03 2.21E-02 20 177 "ABAT,MAPT,SORBS1,TAGLN3,ALDH4A1,FYN,ADGRB2,RGL1,RND1,GLS,HAP1,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,PLPPR4,KCNK2,EFNA3" Drug CID000005658 NSC93767 Stitch 2.72E-05 8.83E-01 2.04E-03 2.24E-02 8 32 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1" Drug CID004369171 Al 6629 Stitch 2.73E-05 8.86E-01 2.05E-03 2.25E-02 19 163 "ADGRV1,GAD2,GFAP,RGL1,NPPA,GRIA1,GRIA4,P2RX7,ZFP91,PAX6,RGMA,KCNA4,KCNA6,SLC17A6,RGR,RLBP1,ELAVL3,ROM1,OLIG2" Drug 5101_UP Prednisolone [50-24-8]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.78E-05 9.02E-01 2.07E-03 2.27E-02 21 192 "ACTN2,AGT,DOCK10,TNIK,NDUFA5,VAMP1,KAZN,HAP1,GRIK4,ADAMTS8,SEZ6L,HPSE2,NRXN2,MICAL2,PLCH2,KCND3,SRGAP3,KCNMA1,NAV2,ATN1,RGS10" Drug 4429_UP "ICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.78E-05 9.02E-01 2.07E-03 2.27E-02 21 192 "NDRG2,FGF1,ANK2,PKNOX2,NCDN,PHLDB1,RND1,CRB1,NEURL1,PADI2,TPM3,MAGI1,HPSE2,CABP1,IFFO1,FEZ1,PTAFR,ITIH2,MAGI2,RABGAP1L,VWA5A" Drug 5206_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.78E-05 9.02E-01 2.07E-03 2.27E-02 21 192 "KIAA1109,APC,ZNF365,ASPH,FYN,WDTC1,TNIK,ZCCHC24,NMNAT2,FAM168A,WSCD1,HAP1,PCDH8,SERPINE2,DNAJC12,SULT4A1,SDC3,PTCH1,RALGDS,SEC61A2,EFNA3" Drug CID000003007 amphetamine Stitch 2.79E-05 9.05E-01 2.07E-03 2.27E-02 27 284 "ADCY2,SNCB,SOX10,GAD2,SYT4,CACNA1E,ZEB1,CAMK2A,CAMK2G,GRIA1,GRIA2,GRIA4,GRM3,CCKBR,PAH,HPS5,PDYN,NTSR2,CHRM1,CAMKV,PRKCG,PKN2,PRKCZ,KLK6,SLC17A6,CAMK1G,EEF1A2" Drug CID000000951 noradrealine Stitch 2.84E-05 9.23E-01 2.11E-03 2.31E-02 44 575 "ACHE,ADCY2,RYR1,ADORA1,ADORA3,TUBB4A,AGT,ACTL6B,API5,SHANK2,ASCL1,SNAP25,ATP1A2,ATP1A3,ABCC8,NODAL,CACNA1A,CACNA1E,NPPA,CACNB2,NUCB1,GRIN1,LEFTY2,P2RX7,PAH,HRH3,PDYN,CHGA,CHRM1,CHRNB2,PIK3CD,UBTF,SULT4A1,P2RY12,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,KLK6,TUBB2B,PYGM,CACNG7" Drug CID000444055 AC1L9FMM Stitch 2.85E-05 9.26E-01 2.11E-03 2.31E-02 12 73 "SLC1A2,SLC1A6,SLC1A7,SLC6A9,HAP1,NUCB1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 3715_UP Delcorine; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.00E-05 9.75E-01 2.22E-03 2.43E-02 21 193 "CDHR1,ACTN2,KIAA1109,C1orf61,ANK1,RASA3,APBB1,SLC1A7,DNAH17,SCN3B,GAD2,ZSWIM8,SLCO1C1,GNG3,DDR2,OPCML,CHI3L2,JAM2,VCAN,MAGI2,DTNA" Drug 6993_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.15E-05 1.00E+00 2.31E-03 2.53E-02 20 179 "MAPT,F3,ADD3,SYBU,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,VAMP1,PADI2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,SIDT2,EFNA3" Drug 5336_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.15E-05 1.00E+00 2.31E-03 2.53E-02 20 179 "ADD3,TUBB4A,FHL1,SYBU,PKNOX2,FYN,ZCCHC24,RGL1,ACSBG1,GLS,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,TMCC2,NAV2,EFNA3" Drug CID006426631 Rp-cAMPS Stitch 3.24E-05 1.00E+00 2.36E-03 2.59E-02 21 194 "MAG,ADCYAP1R1,ADORA1,ADORA3,ACTL6B,WDTC1,NODAL,CACNB2,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GUCY1A2,PDE2A,PDE3B,CHRM1,SLC22A6,PRKACB,PRKCG,PTHLH" Drug 4488_DN Amrinone [60719-84-8]; Down 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.24E-05 1.00E+00 2.36E-03 2.59E-02 21 194 "MAPT,CLIP1,FGF1,APBB1,CCDC88A,EMC1,ADGRB2,ASTN2,MYRF,NUMA1,TNS1,NMT2,MICAL1,MAPK8,KIAA0513,RAB5B,ATG16L1,RAP1GAP,DTNA,PLEKHO1,LRRC23" Drug 6173_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.24E-05 1.00E+00 2.36E-03 2.59E-02 21 194 "ASIC1,EMID1,FOXG1,PDE8B,ATP1A3,NFASC,NCAM1,BTRC,NRGN,NUCB1,GUCY1A1,NEURL1,PADI2,PTGDR2,RBFOX2,LILRA4,SULT4A1,KCNC1,ATN1,ABCC9,EFNA3" Drug CID000004737 pentobarbital Stitch 3.25E-05 1.00E+00 2.36E-03 2.59E-02 23 224 "ASIC1,ADORA1,ADORA3,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,BCO1,SCN3B,MLC1,NPPA,GRIA1,GRIA2,GRIA4,GRIK2,GRM3,ASIC3,CHRNB2,PRKCG,PKN2,PRKCZ,KCNH1" Drug CID000002798 clofilium Stitch 3.28E-05 1.00E+00 2.38E-03 2.62E-02 12 74 "KCNK10,RBPJ,KCNA1,KCNA2,KCNA4,KCNA6,KCND3,KCNH1,KCNK1,KCNK2,KCNMA1,KCNQ2" Drug CID000017248 tetrapentylammonium Stitch 3.30E-05 1.00E+00 2.39E-03 2.62E-02 6 17 "KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCNMA1" Drug 5484_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.41E-05 1.00E+00 2.46E-03 2.69E-02 20 180 "ADD3,TUBB4A,SYBU,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,JAKMIP2,PID1,TTLL7,EFNA3,RASGRP2" Drug 4694_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.41E-05 1.00E+00 2.46E-03 2.69E-02 20 180 "SERPINA3,ADORA1,ASIC4,SLC6A9,PDE8B,CCDC181,NCAM1,ACSBG1,GPM6B,USP2,GPR37L1,HPSE2,CRMP1,PTPRD,KCNMA1,NAV2,DSCAM,SSPN,SIDT2,RASGRP2" Drug 4072_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.41E-05 1.00E+00 2.46E-03 2.69E-02 20 180 "DPF1,ABAT,TUBB4A,TESK2,SORBS1,TAGLN3,BRINP2,TNIK,ZCCHC24,RGL1,RND1,CDK5R2,USP2,PCDH9,DNAJC12,PTCH1,PLPPR4,SRGAP3,EFNA3,VWA5A" Drug CID006914597 2cmo Stitch 3.49E-05 1.00E+00 2.48E-03 2.72E-02 4 6 "GRIA1,GRIA2,GRIA4,GRM3" Drug 2411_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "ABAT,CDHR1,SYNDIG1,CLIP1,KIAA1109,FOXG1,PKP4,APC,GPR153,ZCCHC24,EMC1,GLS,GPM6B,NUMA1,OMG,OPCML,TNS1,VCAN,MAGI2,KCND3,DSCAM" Drug 4263_UP Primaquine diphosphate [63-45-6]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "ABAT,BBOX1,HPCAL4,MOBP,ASTN1,B3GALT2,NCAM1,VAMP1,GRIK3,TF,P2RX7,CHGA,CADM1,NRXN2,ST8SIA5,NECAB2,IGSF1,EDRF1,KCNC1,RASGRF1,ABCC9" Drug 6066_UP Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "ASIC4,CDC42BPA,DOCK10,SLC2A5,ATP2B2,ZSWIM8,NPAS3,PHLDB1,CAMK2G,PSD3,P2RX7,KCNK10,SLC22A6,SULT4A1,OSBPL3,PTAFR,PTHLH,ATN1,ABCC9,LRRC23,RASGRP2" Drug 4657_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "APC2,PLA2G6,PKNOX2,SLC6A9,BRINP2,ATP2B2,B3GALT2,MYH7,ADGRB2,NPAS3,ALDH1L1,GRIK3,USP2,SEZ6L,GPR37L1,ADGRG1,CHGA,POU3F2,RGS6,ITIH2,RGR" Drug 3124_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "PRR5L,CEND1,FOXRED2,FOXG1,C1orf61,CDC42BPA,ANK3,RPH3A,GPR153,TAGLN3,SOX10,GPM6B,CACNB2,OMG,NMT2,SULT4A1,BEST1,MAPK10,PTCH1,PTPRD,SV2A" Drug 2924_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.50E-05 1.00E+00 2.48E-03 2.72E-02 21 195 "MAPT,ADCY2,ADORA1,PLA2G6,ASIC4,C1orf61,SLC1A7,SLCO1A2,ALDH4A1,WDTC1,GAD2,KAZN,GNG4,GPM6B,ATP13A2,JAM2,SULT4A1,CTNND2,ZBTB16,DNAJC6,ABCC9" Drug CID000002519 caffeine Stitch 3.50E-05 1.00E+00 2.48E-03 2.72E-02 43 562 "MAG,ADCY2,RYR1,CDC7,ADORA1,ADORA3,ASIC4,PDE8B,ATM,ATP2B2,MYBPC1,GPR162,NODAL,CACNA1A,CACNA1E,CACNB2,BRSK2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,P2RX7,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,CHRNB2,DNAJC12,P2RY12,PNKD,PTPA,PRKACB,KCNMA1,PYGM,SEC61A2,CACNG7,LPAR6" Drug CID000005304 strychnine HCl Stitch 3.69E-05 1.00E+00 2.59E-03 2.84E-02 20 181 "ABAT,ASIC1,ADGRV1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC1A7,SCN3B,GFAP,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,ASIC3,CHRM1,CHRNB2,PTCH1" Drug 3688_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.69E-05 1.00E+00 2.59E-03 2.84E-02 20 181 "DPF1,ABAT,SORBS1,TAGLN3,SNCB,FYN,TNIK,ADGRB2,NFASC,RGL1,RND1,USP2,TNS1,PCDH9,PIK3CD,DNAJC12,FEZ1,NOS1AP,RIMS3,EFNA3" Drug 334_DN 6-mercaptopurine monohydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "ARID1A,FOXRED2,ANK2,ITSN1,GAS7,ASCL1,TNIK,CADM3,GLS,KAZN,BTRC,GPM6B,TMEM151B,GRIA4,TMPRSS5,CAMKV,PIK3CD,FLRT1,PACSIN1,VCAN,PRDM2" Drug 2270_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "MAG,SLC6A9,SHANK2,DLL3,B3GAT1,FYN,ATP2B2,KIF21B,ADGRB2,ACSBG1,GLS,PSD3,GUCY1A2,PTGDR2,SEZ6L,VCAN,SDC3,TOX,KCNMA1,RAB3IL1,DNAH9" Drug 4191_UP Conessine [546-06-5]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "APC2,NLGN4X,SCN3A,SEMA6C,APC,NTNG1,B3GALT2,TNIK,KIF21B,ADGRB2,BTRC,GPR17,DDR2,DAAM2,PDE4B,IFFO1,CTNND2,PLPPR1,KCND3,SRGAP3,SIDT2" Drug 490_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "ANK2,MSR1,GAD2,GART,NPPA,HAP1,GRIA4,GRIN1,GUCY1A1,NEURL1,TNS1,CDH10,SEZ6L,CHRNB2,IFFO1,KCNJ9,RAD52,SUSD4,ATN1,DSCAM,ELAVL4" Drug 3720_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "EMID1,ADCY2,PLA2G6,TRIM46,RASA3,SLC2A5,PKNOX2,GAD2,NPAS3,ALDH1L1,INKA2,FAM168A,GPR17,HAP1,PCDH9,CDH8,PDE4B,CADM1,SPATA6,NOS1AP,PROX1" Drug 3682_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "ABAT,NDRG2,DOCK10,GAS7,SLC14A1,TAGLN3,SNAP25,ATP2B2,MYRF,GPM6A,KCNK10,PADI2,TNS1,ZMYND8,POU3F4,ATRNL1,MAGI2,KCND3,NUP214,RGS7,EFNA3" Drug 3171_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "AGT,ANK1,ANK2,SORBS1,MSR1,SLCO1A2,SORCS3,ALDH4A1,CCDC181,NEUROD1,GPM6B,ACSL6,HAP1,GUCY1A1,KCNK10,NECAB2,NOS1AP,MASP1,TOX,DTNA,NUP214" Drug 5510_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "MDM4,AGT,MOBP,PKNOX2,DNAH17,SNAP25,KIF21B,KAZN,CACNA1A,CDH10,SEZ6L,PLEKHB1,PIK3CD,TOX,PRDM2,PTPRD,SV2A,RALGDS,ATG16L1,DTNA,NUP214" Drug 6158_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "ADORA1,ASIC4,FOXG1,TACC2,BCAS1,SLCO1A2,INKA2,PHLDB1,MYRF,WWC1,ACSL6,HAP1,GRIA4,GRIN1,PTGDR2,BEST1,CHD5,DSCAM,RASGRF1,ST8SIA3,RCAN2" Drug 3817_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "CEND1,PLA2G6,SEMA6A,MOBP,AMPH,ANK3,APC,CDK5R2,INA,P2RX7,CELF3,PDE2A,CHI3L2,CADM1,POU3F2,SNCAIP,MAGI2,ATN1,ABCC9,RGS10,VWA5A" Drug 2277_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "ADORA3,SLC1A2,SLC2A5,MSR1,SLC6A9,DLL3,ATP1A3,SOX10,NPAS3,NDUFA5,SLCO1C1,ABCC8,ADGRL3,WSCD1,PSD3,GPR37L1,EDRF1,PTCH1,PRDM2,MAGI2,KCNJ4" Drug 3789_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "CEND1,FABP7,TUBB4A,SLCO1A2,CADM3,ADGRB2,ALDH1L1,GFRA1,ACSBG1,PRUNE2,ATF7,OPCML,P2RX7,ADGRG1,CADM1,NECAB2,PTPRD,NTM,ATN1,VWA5A,ELAVL4" Drug 2764_DN Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.78E-05 1.00E+00 2.59E-03 2.84E-02 21 196 "PAQR6,WLS,GPR153,ATM,INKA2,GNG4,NRGN,NUCB1,RBFOX2,ARHGAP19,PDE3B,ZMYND8,DZIP3,HP1BP3,RABGAP1L,PEX5,NKAIN1,DTNA,RGS10,EFNA3,ABI2" Drug CID000003206 EHNA Stitch 3.82E-05 1.00E+00 2.61E-03 2.86E-02 13 87 "ADAR,ADARB2,ADORA1,ADORA3,APC,AHCYL1,GUCY1A2,PDE1C,PDE2A,PDE3B,PDE4B,DNAH9,SLC17A6" Drug CID005322157 AC1NT1AF Stitch 3.93E-05 1.00E+00 2.62E-03 2.87E-02 7 25 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug CID000003932 linopirdine Stitch 3.98E-05 1.00E+00 2.62E-03 2.87E-02 9 43 "ANK3,ARFGAP1,ATP2B2,TNS1,CHRM1,KCNC1,KCNH1,KCNMA1,KCNQ2" Drug CID000002376 AC1Q3ZOL Stitch 3.98E-05 1.00E+00 2.62E-03 2.87E-02 25 258 "ABAT,ADGRV1,ADORA1,ADORA3,ACTL6B,CSPG5,GAD2,CACNB2,ZEB1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,PDYN,CHRM1,CHRNB2,PTCH1,PRDM2,KCNN3,SLC17A6,DTNA,EEF1A2" Drug 3075_UP Cantharidin [56-25-7]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.00E-05 1.00E+00 2.62E-03 2.87E-02 20 182 "MBP,ACTN2,MOBP,C1orf61,ANK3,SHANK2,CSPG5,CCDC181,TNIK,RND1,VAMP1,NHLH1,GNG4,INA,GUCY1A1,TJP1,PADI2,PMP2,ST8SIA3,LRRC23" Drug 6932_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 2.62E-03 2.87E-02 20 182 "ADD3,TUBB4A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,VAMP1,PCDH9,ACOT7,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,NAV2,RGS10,EFNA3" Drug 7043_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.00E-05 1.00E+00 2.62E-03 2.87E-02 20 182 "ADD3,TUBB4A,FHL1,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,DNAJC6,TMCC2,EFNA3,VWA5A" Drug 2490_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ABAT,MAPT,ARID1A,AGT,FOXG1,PPM1E,ATP2B2,NPAS3,SLCO1C1,NPPA,OMG,SEZ6L,MAGI1,CHI3L2,GDAP1L1,CABP1,DNAJC6,CNIH3,MAGI2,TMCC2,DLG3" Drug 2908_UP Nifurtimox [23256-30-6]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ARID1A,NDRG2,PLA2G6,ANK2,ANK3,AQP4,PDE8B,VAMP1,HAP1,TJP1,KCNK10,DAAM2,CDH10,RBFOX2,CAMKV,POU3F4,MICAL2,PARP11,ATN1,RASGRF1,EPB41" Drug 6372_DN 3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "MAPT,WAC,FGF1,SLC1A7,ALDH4A1,WDTC1,MYRF,GPR17,HAP1,OPCML,USP2,PDE2A,ZMYND8,CHRNB2,PACSIN1,CHD5,STMN4,KCNA2,SMG7,RABGAP1L,ELAVL3" Drug 3769_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ASIC1,PAQR6,SCNN1D,AMPH,AQP4,PDE8B,TAGLN3,ATP1A3,NPAS3,ALDH1L1,NUMA1,CDH8,SEZ6L,SLC22A6,SULT4A1,NECAB2,ITIH2,ATN1,DTNA,ST8SIA3,RASGRP2" Drug 3188_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "FHL1,SLC1A2,SLC14A1,SNAP25,CCDC181,ATP2B2,GAD2,INKA2,SLCO1C1,ROBO3,BTRC,GPM6B,HAP1,PIK3CD,NMT2,CABP1,NECAB2,IFFO1,JAKMIP2,KCNMA1,ATN1" Drug 2819_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "NDRG2,KIAA1109,ASIC4,FHL1,NLGN1,SLC1A7,PKNOX2,SLCO1A2,NEUROD1,RND1,ABCC8,POPDC3,SEMA4A,CAMK2G,MAPK8,PTCH1,PRDM2,KCNK2,KCNMA1,RAB3IL1,SSPN" Drug 4231_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ASIC1,ACTN2,ARID1A,KCNIP2,ADORA1,APC,AQP4,NFASC,NCAM1,PHLDB1,ACSBG1,ADGRL3,HPSE2,CALY,IGSF1,MAPK10,NOS1AP,PTPRD,RASGRF1,SLC6A15,RASGRP2" Drug 3039_UP Equilin [474-86-2]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ABAT,CHST15,PKNOX2,ASCL1,GPR153,SLN,CCDC181,B4GALNT1,HAP1,TGFBR3,INA,GUCY1A1,CDH10,SEZ6L,PLEKHB1,DZIP3,MAGI2,KCND3,TMCC2,RAB3IL1,ABCC9" Drug 6810_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "NDRG2,PLA2G6,ANK1,RASA3,ITSN1,BCO1,FYN,ATP2B2,WDTC1,FAM168A,GLS,PDE1C,ADGRG1,FADS2,CRMP1,RIMS3,KCNK1,SUSD4,ATN1,DTNA,NUP214" Drug 3191_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "SORBS1,MSR1,SLC14A1,ASCL1,NCAM1,GPR162,GFAP,GPM6B,NPPA,HAP1,OLR1,NEURL1,NRXN2,PIK3CD,IFFO1,PKN2,JAKMIP2,TMCC2,ST8SIA3,VWA5A,RASGRP2" Drug 2435_UP Bisacodyl [603-50-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ANK3,AQP4,SHANK2,SLCO1A2,ALDH4A1,CCDC181,WDTC1,NCAM1,CAMSAP2,PSD3,GUCY1A2,CDH10,RBFOX2,ZMYND8,IFFO1,SYTL2,KCNH1,DLG3,RASGRF1,EEF1A2,EPB41L1" Drug 3292_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "EMID1,FOXRED2,MOBP,FOXG1,APBA2,SLC1A7,ASTN1,WDTC1,CADM3,NDUFA5,INKA2,AJAP1,KAZN,CCKBR,TGFBR3,TNS1,CNTN1,MAPK8,NOS1AP,HP1BP3,KCNJ4" Drug 6817_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ADORA1,AGT,HPCAL4,SHANK2,TAGLN3,FYN,ATP2B2,KIF21B,INKA2,WSCD1,NPPA,GRM3,OPCML,SEZ6L,CHRNB2,CNTN1,OSBPL3,PLCH2,EDRF1,RIMS3,SV2A" Drug 6805_UP Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "AGT,KIAA1109,RASA3,GAS7,SORBS1,CCDC88A,WDTC1,MYH7,PHLDB1,CACNA1A,INA,TLL2,SEZ6L,ADGRG1,SULT4A1,VCAN,MAPK10,PTAFR,ELMO1,KCNMA1,CRTAC1" Drug 4559_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ARID1A,MDM4,KCNIP2,KIAA1109,RASA3,AQP4,PKNOX2,NFASC,INKA2,ZEB1,ZFYVE9,PIK3CD,IFFO1,VCAN,CTNND2,PRDM2,AK5,ATN1,ST8SIA3,SIDT2,RASGRP2" Drug 2366_UP Ethisterone [434-03-7]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "FOXRED2,KIAA1109,ANK1,ANK3,CAPRIN2,CADM3,FGF17,VAMP1,P2RX7,SCRG1,PPP2R5C,VCAN,CTNND1,CTNND2,NTM,RABGAP1L,PEX5,RALGDS,ST8SIA3,SIDT2,EPB41L1" Drug 3088_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "MAPT,ACTN2,AMPH,ANK3,PKP4,GPR153,TAGLN3,CCDC181,WDTC1,ALDH1L1,ACSL6,TNS1,NECAB2,DZIP3,EDRF1,STMN4,SMG7,DNM2,SIDT2,EPB41,RASGRP2" Drug 5276_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "DPF1,NDRG2,RYR1,FOXG1,RASA3,SLC1A2,SLC1A7,GAD2,TCF7L2,USP2,CHRNB2,SF1,CRMP1,PRKAB2,SDC3,SMG7,RABGAP1L,SNX27,WIPF2,ATN1,ELAVL3" Drug 3685_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "SLC1A6,PDE8B,SLCO1A2,SCN3B,ADGRB2,ALDH1L1,KAZN,GPM6A,GPM6B,ZEB1,GRIN1,NEURL1,TNS1,IFFO1,ETNPPL,IGSF1,RIMS3,PTCH1,PTPRO,NTM,ARNT2" Drug 2404_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "CDC42BPA,SORBS1,NLGN1,AQP4,NPAS3,RAP1GAP2,GFAP,SLCO1C1,PRUNE2,NUMA1,PSD3,SPX,FLRT1,CRMP1,EDRF1,JAKMIP2,KCNK1,DNAH9,DTNA,LPAR6,RASGRP2" Drug 4702_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ASIC1,NDRG2,FABP7,KIAA1109,SEMA6A,GAS7,PDE8B,BRINP2,ATP1A2,ATP1A3,GPM6B,GRIK2,GRIN1,GUCY1A2,PTGDR2,GPR37L1,CAMKV,MAPK10,PRDM2,FAM13C,ST8SIA3" Drug 5793_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ASIC1,MAPT,EMID1,PLA2G6,RASA3,SHANK2,SLN,NFASC,MYRF,BTRC,GPM6A,NPPA,DAAM2,SEZ6L,CRMP1,NOS1AP,PLPPR1,PLPPR4,PID1,SUSD4,ROM1" Drug 6043_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "ACTN2,RYR1,FGF1,CDC42BPA,RASA3,SORBS1,SLC1A2,RPH3A,SLC1A7,CCDC181,GPR162,PHLDB1,PRUNE2,OLR1,TNS1,HPSE2,CHI3L2,VAV2,NOS1AP,PTAFR,RASGRF1" Drug 3836_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.07E-05 1.00E+00 2.62E-03 2.87E-02 21 197 "SEMA6A,C1orf61,RASA3,ASPH,ALDH4A1,INKA2,PRUNE2,CACNB2,ZEB1,NUMA1,NEURL1,TPM3,ADGRG1,CHI3L2,GDAP1L1,ZFYVE9,SULT4A1,KCNJ4,RABGAP1L,RASGRF1,NUP214" Drug CID000061671 vanadyl Stitch 4.21E-05 1.00E+00 2.68E-03 2.94E-02 28 307 "MAG,MBP,AGT,FGF1,MOBP,MOG,PDE8B,DNAH17,FYN,ATP2B2,OLR1,OMG,PCDH8,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CADM1,PIK3CD,PTPA,PRKACB,PRKCG,CTNND1,MAPK8,MAPK10,PTPRZ1,DNAH9" Drug CID000003857 2-amino-3-phosphonopropionic acid Stitch 4.31E-05 1.00E+00 2.68E-03 2.94E-02 12 76 "GAD2,MYH7,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,CHRM1,VCAN,PRKCG" Drug 3638_UP Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ASIC1,RYR1,KIAA1109,NLGN1,SLC1A7,PKNOX2,ASCL1,ATP2B2,CADM3,EMC1,PHLDB1,RND1,AJAP1,GPM6A,OMG,KCNK10,ZFYVE9,DNAJC6,KCND3,RAD52,EN2" Drug 3801_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "SORBS1,SLC2A5,PKNOX2,SORCS3,SCN3B,ADGRB2,LMO3,SLCO1C1,GPR17,USP2,KCNK10,PDE2A,CHI3L2,KIAA1549L,CAMKV,NOS1AP,SUSD4,DSCAM,ABCC9,VWA5A,EPB41" Drug 4422_UP Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "DPF1,NDRG2,SEMA6A,AMPH,SLN,COLGALT2,GLS,GNG3,WSCD1,ATF7,OMG,INA,TNS1,ZMYND8,FADS2,SULT4A1,SNCAIP,VCAN,PTHLH,STMN4,RET" Drug 6201_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "EMID1,SYNDIG1,RYR1,TUBB4A,FGF1,C1orf61,SLC1A7,MSR1,DLL3,B3GAT1,ZSWIM8,NCAM1,CDK5R2,CRB1,GUCY1A2,CHI3L2,POU3F2,RAD52,DSCAM,FAM13C,PAK5" Drug 2020_UP Azacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "MBP,ADORA1,PLA2G6,SLC2A5,PDE8B,CADM3,ADGRB2,ALDH1L1,GJB1,GLS,CACNA1A,NUCB1,OMG,LILRA4,ZMYND8,DUSP26,CAMKV,PACSIN1,TMCC2,RAP1GAP,NUP214" Drug 4278_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ACTN2,RYR1,TRIM46,APC,NTNG1,SLCO1A2,ATP1A3,ATP2B2,INKA2,AJAP1,ACSBG1,VAMP1,GPR17,PADI2,HRH3,PDE4B,CADM1,CAMKV,MAPK8,PSD,RIMS3" Drug 2267_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "APC2,SYNDIG1,MOBP,CDC42BPA,DOCK10,APC,DLL3,SOX10,GLS,POPDC3,ATF7,KCNK10,VCAN,MAPK8,NOS1AP,PTAFR,ITIH2,RABGAP1L,TMCC2,KCNMA1,ATN1" Drug 6079_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "DPF1,MAG,APC2,RYR1,ANK1,GAS7,RPH3A,SLC2A5,GPR153,SLCO1A2,DLL3,SOX10,COLGALT2,GRIN1,TUB,ELMO1,STMN4,KCND3,KCNH1,ST8SIA3,RASGRP2" Drug 2246_UP Isoniazid [54-85-3]; Up 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "FOXG1,AMPH,CDC42BPA,BCAN,NLGN1,PKNOX2,FYN,NCDN,VAMP1,POPDC3,GNG3,GPM6A,INA,SEZ6L,ADGRG1,ASIC3,SULT4A1,CRMP1,KCNMA1,DNAH9,CAMK1G" Drug 6625_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "EMID1,CEND1,ADORA1,FOXG1,B3GAT1,CCDC181,ALDH1L1,BTRC,ZEB1,TMEM151B,GRIA1,OPCML,PADI2,PCDH9,CDH10,PDE4B,CADM1,PKN2,MAPK10,VWA5A,RASGRP2" Drug 2402_UP Chenodiol [474-25-9]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "F3,ANK1,DOCK10,BCAS1,ZCCHC24,ZSWIM8,SLCO1C1,PRUNE2,WSCD1,GPM6B,NEURL1,RBFOX2,TPM3,PDE4B,NMT2,CNTN1,MAPK8,DLG2,DSCAM,EEF1A2,EFNA3" Drug 4225_UP Carcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ACHE,CDHR1,MOBP,PKP4,NTNG1,GAS7,NFASC,INA,NEURL1,TNS1,CHGA,FEZ1,PLCH2,NCAN,ITIH2,PTPRD,SRGAP3,KCNJ9,SLC17A6,RGS10,RASGRP2" Drug 5446_UP Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "DPF1,ADORA1,HPCAL4,FOXG1,SELL,APC,GAS7,SLC1A2,SLCO1A2,ATP2B2,WDTC1,VAMP1,ZEB1,HAP1,USP2,PTGDR2,RIMS3,JAKMIP2,KCNJ4,RASGRF1,NUP214" Drug 4254_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "APC2,SEMA6A,ASIC4,GAS7,RND1,ACSBG1,NHLH1,CACNA1A,PRUNE2,TPM3,ASIC3,CHRNB2,CADM1,MAPK10,KCNC1,KCNQ2,RAD52,DTNA,ABCC9,USH1C,LRRC23" Drug 3583_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ADORA1,SEMA6A,ASIC4,RPH3A,PKNOX2,B3GAT1,GPM6A,DDR2,OPCML,CDH10,PDE1C,PMP2,BEST1,POU3F2,SNCAIP,PTCH1,SV2A,KCNJ4,EFNA3,VWA5A,ELAVL3" Drug 2488_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "PRR5L,RYR1,AGT,KIAA1109,FOXG1,CADM3,NFASC,GRIK2,GUCY1A2,PDE2A,PHKG1,CCSER2,SULT4A1,MAPK8,PROX1,MAGI2,SMG7,KCND3,RGS10,SSPN,RASGRP2" Drug 5410_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "PLA2G6,FHL1,MSR1,SHANK2,ATM,WDTC1,KIF21B,COLGALT2,ALDH1L1,NEUROD1,POPDC3,GUCY1A2,PDE3B,ARHGAP22,MAPK8,NOS1AP,PROX1,PTHLH,KCNK2,PARP11,DSCAM" Drug 4253_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "TTYH1,SEMA6A,SELL,APBB1,AQP4,ASCL1,NCAM1,SLCO1C1,CDK5R2,PCDH9,SEZ6L,PCSK2,ARHGAP22,PHKG1,CTNND2,MAPK8,PTHLH,MAGI2,RGS10,EFNA3,ELAVL3" Drug 2149_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "TESK2,APC,GAS7,ARFGAP1,ASPH,WDTC1,ZCCHC24,GAD2,BCL2L2,KAZN,TCF7L2,GPR19,CAMK2G,TNS1,RBFOX2,ZFYVE9,RAB3IL1,RGS10,ABI2,VWA5A,RASGRP2" Drug 4139_DN Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "DPF1,ACTN2,ADORA1,KIAA1109,FHL1,HPCAL4,C1orf61,AMPH,APBA2,SORBS1,TAGLN3,ALDH1L1,NEUROD1,PSD3,HMGB1,NOS1AP,ITIH2,PTPRO,KCND3,RAB3IL1,NUP214" Drug 3798_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "MAG,SYNDIG1,PLA2G6,HPCAL4,MOBP,TRIM46,SLC1A6,SCN3B,RND1,PRUNE2,ATF7,GPR17,GUCY1A2,PTGDR2,CAMKV,POU3F2,TOX,RABGAP1L,KCNQ2,FAM13C,RGS10" Drug 4187_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "TTYH1,ADCY2,SLC2A5,SHANK2,SLC14A1,ASCL1,B3GAT1,TNIK,CADM3,MYRF,CDK5R2,BTRC,ADGRL3,KCNK10,NECAB2,IFFO1,NSD2,KCND3,DNAH9,DTNA,PLEKHO1" Drug 3053_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ABAT,NDRG2,HPCAL4,CDC42BPA,ANK3,SLC1A2,PKNOX2,ALDH4A1,TNIK,WSCD1,GPR19,ATP13A2,USP2,REPS2,PTGDR2,PCSK2,SULT4A1,CHD5,PTHLH,MAGI2,ABCC9" Drug 2397_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "CDC42BPA,APC,GPR153,ASPH,NPAS3,CAMSAP2,WWC1,PRUNE2,GRIN1,PTGDR2,TPM3,PDE4B,ZFYVE9,MAPK8,EDRF1,MASP1,RAD52,SUSD4,ST8SIA3,ARHGEF10L,RAVER2" Drug 4147_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.39E-05 1.00E+00 2.68E-03 2.94E-02 21 198 "ACTN2,SLC2A5,PKNOX2,TAGLN3,ATP2B2,MYBPC1,KIF21B,NPAS3,NCAM1,LMO3,PRUNE2,WSCD1,PDE2A,JAM2,CAMKV,PIK3CD,VCAN,PSD,DNAJC6,KCNMA1,RCAN2" Drug 3868_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.52E-05 1.00E+00 2.75E-03 3.02E-02 19 169 "ADD3,TUBB4A,HPCAL4,SORBS1,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PIK3CD,DNAJC12,PTAFR,DNAJC6,TMCC2,VWA5A,RASGRP2" Drug CID003083599 Sulf Stitch 4.58E-05 1.00E+00 2.78E-03 3.05E-02 10 54 "MAG,MBP,FGF1,MOG,B3GAT1,PTPN5,TNR,HPR,SDC3,ARHGEF4" Drug 3643_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.67E-05 1.00E+00 2.79E-03 3.05E-02 20 184 "TUBB4A,AGT,SORBS1,PKNOX2,FYN,KIF21B,CPLX2,RGL1,RND1,ACSBG1,GLS,CDK5R2,PAH,PIK3CD,DNAJC12,RIMS3,PTAFR,DNAJC6,EFNA3,RASGRP2" Drug 4188_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "TTYH1,RTN1,SEMA6A,PKNOX2,SORCS3,KIF21B,CADM3,LMO3,ACSBG1,CCKBR,NEURL1,PTGDR2,SEZ6L,PDE4B,ZMYND8,HPSE2,PMP2,NTM,ARNT2,DSCAM,RASGRF1" Drug 4691_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "ACTN2,FOXG1,ANK1,RASA3,GAS7,SLC1A7,CCDC88A,PHLDB1,POPDC3,CAMK2G,OPCML,USP2,PDE4B,CNTN1,CHD1L,CRMP1,RGS6,RIMS3,TTLL7,ROM1,RASGRP2" Drug 4957_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "KIAA1109,MSR1,CCDC88A,GPR153,SLCO1A2,B3GAT1,KIF21B,PHLDB1,NEUROD1,GPM6B,ATF7,CACNB2,CNTN1,CRMP1,VCAN,PRDM2,KCND3,NTM,TMCC2,VWA5A,ELAVL4" Drug 6466_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "CEND1,MDM4,KIAA1109,C1orf61,CDC42BPA,MSR1,ALDH4A1,WDTC1,ZCCHC24,SOX10,GAD2,AJAP1,KAZN,USP2,PDE3B,CHRNB2,SDC3,PTHLH,KCNK1,KCNMA1,KCNN3" Drug 6462_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "TUBB4A,MOBP,SLC1A2,BCO1,SLC8A2,PDE8B,ASPH,SNAP25,DKK3,ZCCHC24,KIF21B,AJAP1,ARHGEF7,OPCML,HPCA,KIAA1549L,VAV2,TENM4,MAPK10,KCNMA1,LRRC23" Drug 4494_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "APC2,ARID1A,ADORA1,C1orf61,RPH3A,PKNOX2,DDX25,ATP1A3,FYN,MYT1L,RND1,SLCO1C1,GPM6A,GPR17,NEURL1,SEZ6L,TPM3,PDE3B,ITIH2,MAGI2,L1CAM" Drug 5954_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "FOXG1,DNAH17,EMC1,PSD3,GRIN1,TF,NEURL1,PCDH9,RBFOX2,ZFYVE9,VAV2,NECAB2,CHD1L,MAPK10,NOS1AP,RIMS3,JAKMIP2,PTHLH,KCND3,TMCC2,NUP214" Drug 2579_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "ABAT,CEND1,FOXG1,ANK3,PKP4,SLC1A2,GPR153,TAGLN3,PALLD,PHLDB1,GNG4,PSD3,INA,NEURL1,CDC42,RBFOX2,PDE3B,POU3F2,KCND3,PARP11,EFNA3" Drug 4115_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "ACTN2,RYR1,KIAA1109,ANK1,DOCK10,AQP4,ASPH,RND1,AJAP1,OMG,LILRA4,FADS2,PMP2,POU3F2,PLCH2,VCAN,RAB3IL1,ATN1,RGS10,SSPN,VWA5A" Drug 3625_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "ASIC1,EMID1,FHL1,SELL,RASA3,GAS7,ASCL1,ATP1A2,CADM3,SOX10,EMC1,RND1,ACSBG1,WSCD1,INA,SULT4A1,PACSIN1,MICAL2,CA10,RABGAP1L,TMCC2" Drug 3073_UP Flucytosine [2022-85-7]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "CDC42BPA,ANK3,BCAS1,RPH3A,CGREF1,DNAH17,TAGLN3,GAD2,ALDH1L1,GNG3,PSD3,PCDH9,CHGA,CNTN1,STMN4,SV2A,NAV2,DSCAM,EEF1A2,SSPN,EPB41" Drug 2379_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "PLA2G6,CDC42BPA,PDE8B,GPR153,TAGLN3,ASPH,PALLD,ZCCHC24,SOX10,ZSWIM8,NEUROD1,ASTN2,WSCD1,TCF7L2,USP2,RBFOX2,SERPINE2,CCSER2,BEST1,DZIP3,DTNA" Drug 4748_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "EMID1,CEND1,KCNIP2,TUBB4A,ANK1,APBA2,BCAN,SLC1A2,SLC2A5,B3GAT1,ACSBG1,TGFBR3,NEURL1,DAAM2,TPM3,PACSIN1,RIMS3,KCND3,RAD52,LMO1,RASGRP2" Drug 4071_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "FGF1,AQP4,SLC1A6,SLN,ASTN1,B3GAT1,ATP1A3,ACSBG1,ASTN2,CACNB2,BRSK2,LILRA4,ARHGEF4,MAPK8,STMN4,PLPPR4,DTNA,ST8SIA3,RGS10,SIDT2,LRRC23" Drug 3299_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "MDM4,KLRC4,RYR1,TUBB4A,FOXG1,C1orf61,ANK2,ITSN1,APC,SLC1A7,SCN3B,GLS,GNG4,BTRC,CAMK2G,GRIK3,SULT4A1,SNCAIP,DZIP3,JAKMIP2,SEC61A2" Drug 3095_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.73E-05 1.00E+00 2.79E-03 3.05E-02 21 199 "SYNDIG1,ARID1A,SEMA6A,C1orf61,MSR1,TAGLN3,NPPA,GPR19,GRIN1,OMG,INA,TNS1,RBFOX2,LILRA4,CHI3L2,CCSER2,SV2A,DNM2,RAD52,TTLL7,SSPN" Drug CID000003838 KN-62 Stitch 4.92E-05 1.00E+00 2.89E-03 3.17E-02 23 230 "SLCO1A2,SNAP25,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,GRIA2,GRIA4,GRIK4,GRM3,P2RX7,CHRM1,CAMKV,P2RY12,PTPA,PRKACB,CALY,PRKCG,MAPK8,KCND3,CAMK1G,NUP214" Drug CID000004253 morphine hydrochloride Stitch 5.01E-05 1.00E+00 2.90E-03 3.18E-02 38 481 "ABAT,ACLY,ADCY2,FOXM1,ASRGL1,SLC1A2,CSPG5,B3GAT1,SOX10,NCAM1,GFAP,GFRA1,NODAL,CACNA1A,CACNA1E,PRLHR,GRIA1,GRM3,CCKBR,LEFTY2,TGFBR3,PAH,HRH3,PDYN,CHRM1,SULT4A1,RGS6,PRKACB,PRKCG,MAPK8,MAPK10,KCNA1,KCNA6,KCNH1,NTM,L1CAM,CAMK1G,RGS7" Drug 1637_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.05E-05 1.00E+00 2.90E-03 3.18E-02 20 185 "ADD3,PPM1E,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PADI2,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,NAV2,GNE,EFNA3" Drug 4445_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.05E-05 1.00E+00 2.90E-03 3.18E-02 20 185 "NTNG1,GAS7,CSPG5,ATM,CADM3,NPAS3,RND1,GNG4,PRUNE2,ATF7,GPR19,GUCY1A2,PDE4B,CHI3L2,ZFYVE9,MAPK8,SYNC,MAGI2,PARP11,ATN1" Drug 6771_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "RYR1,TUBB4A,ASIC4,FHL1,C1orf61,APBA2,SLC14A1,SLN,ALDH4A1,PRUNE2,NRGN,HAP1,NEURL1,TNS1,PDE1C,CHRNB2,NECAB2,POU3F4,NOS1AP,GNE,SSPN" Drug 251_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "FOXRED2,ASIC4,ANK1,RASA3,APBA2,EIF4G3,ATP2B2,NPAS3,GLS,ASTN2,KAZN,WWC1,GUCY1A2,SEZ6L,DZIP3,SDC3,MAPK8,KCNJ4,PYGM,L1CAM,NUP214" Drug 6150_UP Ramipril [87333-19-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "MBP,ADORA1,NTNG1,SLC1A2,PKNOX2,ASCL1,SLCO1A2,ALDH4A1,MYBPC1,ALDH1L1,VAMP1,ADGRL3,WWC1,GPR19,GRIN1,CELF3,ASIC3,SLC22A6,PROX1,ATN1,DSCAM" Drug 5785_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "DPF1,TTYH1,MAPT,SYNDIG1,FGF1,BBOX1,TAGLN3,INKA2,CACNB2,NEURL1,CDH8,SEZ6L,ADGRG1,CNTN1,COL9A2,PKN2,KCNA2,KCNC1,RAD52,ELAVL3,ROM1" Drug 2894_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "ASIC1,PLA2G6,FOXG1,ASCL1,RND1,GLS,PRUNE2,CACNB2,HAP1,NUMA1,PDE4B,CHI3L2,TENM4,ATRNL1,VCAN,JAKMIP2,CNIH3,MAGI2,RABGAP1L,TMCC2,ELAVL3" Drug 6839_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "NDRG2,MOBP,AMPH,GAS7,ASPH,WDTC1,ZCCHC24,AJAP1,GNAS,CACNA1A,WSCD1,PSD3,GUCY1A2,NEURL1,ADGRG1,CAMKV,SULT4A1,CNIH3,MAGI2,NTM,VWA5A" Drug 6836_UP Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "RASA3,SLITRK3,AQP4,SLC14A1,TAGLN3,ASPH,KIF21B,ALDH1L1,GNG3,CACNA1A,WSCD1,TPM3,CAMKV,ATRNL1,VCAN,SYNC,KCNC1,KCND3,KCNMA1,ATN1,RASGRP2" Drug 6032_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "KCNIP2,SEMA6A,FGR,ANK1,TAGLN3,CADM3,CPLX2,NCAM1,INKA2,RGL1,GNAS,GNG3,GRIA4,GUCY1A2,PDE2A,SNCAIP,CHD5,MASP1,CA10,KCNJ9,ATN1" Drug 4091_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "MAG,GAS7,ST8SIA1,SLC6A9,DDX25,ATP1A2,SPART,NCAM1,NDUFA5,GFRA1,NEUROD1,GUCY1A2,NEURL1,DAAM2,SEZ6L,CHI3L2,DUSP26,BEST1,RIMS3,KCND3,OLIG2" Drug 3776_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "EMID1,EXTL1,ADORA1,PKP4,PDE8B,ASPH,GFRA1,RND1,GPM6B,NPPA,NUMA1,TNS1,RGS6,PLCH2,PTAFR,SRGAP3,KCNMA1,RAD52,DTNA,RGR,EFNA3" Drug 604_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "ASIC1,PAQR6,CEND1,FGR,ANK3,APBA2,ASCL1,GLS,GNG3,NRGN,HAP1,PTBP2,OMG,PHKG1,CADM1,CAMKV,DLG3,KIF2A,SUSD4,ABCC9,ARHGEF10L" Drug 2722_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "ACTN2,TUBB4A,FHL1,HPCAL4,SLC1A2,SLC14A1,ALDH4A1,SLCO1C1,BTRC,NPPA,OMG,NEURL1,KCNK10,CHRNB2,FLRT1,SPATA6,CRMP1,DZIP3,ITIH2,RCAN2,RASGRP2" Drug 6038_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "MOBP,PKNOX2,ZSWIM8,COLGALT2,ALDH1L1,AJAP1,GNG3,CNTN2,CACNB2,ZEB1,OMG,SPX,PCDH9,HPSE2,MAPK10,ZBTB16,PSD,NTM,ATN1,RASGRF1,LRRC23" Drug 5460_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.09E-05 1.00E+00 2.90E-03 3.18E-02 21 200 "MAPT,ACTN2,HPCAL4,APC,TAGLN3,ZCCHC24,CADM3,NEUROD1,ACSBG1,GLS,GRIA1,HRH3,ADGRG1,CHRNB2,PIK3CD,SULT4A1,CRMP1,ARHGEF4,MAPK10,ATN1,SSPN" Drug CID000132434 Ro 15-2041 Stitch 5.20E-05 1.00E+00 2.96E-03 3.25E-02 7 26 "PDE8B,NPPA,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug ctd:C086401 pentabromodiphenyl ether CTD 5.30E-05 1.00E+00 3.02E-03 3.31E-02 79 1270 "SDE2,MAPT,ACHE,MEG3,ARID1A,SLC25A25,HHATL,FABP7,TOMM40L,AGT,SCN4B,FGF14,C1QTNF4,GAS7,SLC7A14,CCDC88A,AHCYL1,KIF1B,DNER,NAP1L2,NASP,NCAM1,C11orf87,GFAP,RGL1,SEPT3,SLCO1C1,NFIA,ARHGEF7,GPM6B,NRGN,CAMK2A,GRIA1,ADAMTS8,TGFBR3,FBXL16,GUCY1A1,TLL2,PCDH8,DCLK1,TPD52,TPM3,PDE1A,ADGRG1,CHRM1,CHRM4,CHRNB2,HNRNPK,JAM2,CADM1,CNTN1,BTF3L4,SLC36A4,CRMP1,TENM4,FMN2,KIAA1755,PRKCZ,PROX1,RIMS3,DPYSL5,PTHLH,CNIH3,PRDM2,CSDE1,OCIAD1,PTPRO,AK5,CALN1,DTNA,L1CAM,SLC6A15,INSYN2,SEC61A2,EFNA3,RBM12,GPR61,RPE65,RCAN2" Drug CID000004178 mexiletine Stitch 5.35E-05 1.00E+00 3.04E-03 3.33E-02 11 66 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,ANK2,ANK3,SCN3B,ASIC3,PCDH15,RET" Drug ctd:C520612 "N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid" CTD 5.47E-05 1.00E+00 3.10E-03 3.40E-02 8 35 "SLC1A2,SLC6A9,SLC8A3,SNAP25,GRIA2,GRID1,GRM3,PPP3CB" Drug CID003272523 NBQX Stitch 5.50E-05 1.00E+00 3.11E-03 3.41E-02 13 90 "SLC1A2,BCO1,GAD2,GFAP,CACNB2,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN" Drug CID000001764 GTP[S] Stitch 5.65E-05 1.00E+00 3.19E-03 3.50E-02 44 592 "ASIC1,RTKN,ADCY2,RYR1,ADORA1,ADORA3,AGT,SCN3A,SCN4B,SCNN1D,ACTL6B,ASIC4,FOXM1,ARFGAP2,SCN3B,RND1,MLC1,GNAS,GNG3,GOLGB1,CACNA1A,CACNA1E,NPPA,CACNB2,GRM3,CCKBR,AIFM1,KCNK10,CDC42,HRH3,ASIC3,CHRM1,PRKACB,CALY,PRKCG,PKN2,PRKCZ,MASP1,PLPPR5,KCNJ4,KCNMA1,DNM2,CACNG7,BSCL2" Drug CID000349960 Sialic acids Stitch 5.74E-05 1.00E+00 3.24E-03 3.55E-02 29 329 "MAG,SERPINA3,LRRC7,MOBP,MOG,SELL,BCAN,NLGN1,ST3GAL3,ST8SIA1,CCDC88A,B4GALNT1,NCAM1,GNAS,ADGRL3,NEU4,TF,OMG,HPR,ST8SIA5,CP,VCAN,KCNA1,NTM,GNE,L1CAM,ST8SIA3,EEF1A2,EPB41" Drug 3979_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.75E-05 1.00E+00 3.24E-03 3.55E-02 19 172 "DPF1,ADD3,TUBB4A,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,NMNAT2,RGL1,RND1,ACSBG1,VAMP1,CDK5R2,PIK3CD,DNAJC12,KIAA0513,VWA5A" Drug CID000115201 philanthotoxin Stitch 5.82E-05 1.00E+00 3.26E-03 3.58E-02 9 45 "PLA2G6,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CHRNB2" Drug CID000001884 7-chlorokynurenic acid Stitch 5.82E-05 1.00E+00 3.26E-03 3.58E-02 9 45 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,PDYN" Drug 5976_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.88E-05 1.00E+00 3.29E-03 3.60E-02 20 187 "TUBB4A,SORBS1,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,CDK5R2,PCDH9,PIK3CD,NMT2,DNAJC12,DNAJC6,JAKMIP2,SRGAP3,EFNA3,VWA5A" Drug 3077_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.88E-05 1.00E+00 3.29E-03 3.60E-02 20 187 "ASIC1,WLS,ANK3,ARHGAP5,CCDC181,TNIK,NCAM1,RGL1,WWC1,PSD3,PCDH9,FEZ1,DZIP3,KIAA0513,RIMS3,DNAJC6,SV2A,TMEM255A,EFNA3,RASGRP2" Drug CID000000906 type-IV Stitch 6.15E-05 1.00E+00 3.43E-03 3.76E-02 26 281 "MAG,SERPINA3,LRRC7,MOBP,MOG,SELL,NLGN1,ST3GAL3,ST8SIA1,STK32C,B4GALNT1,NCAM1,FAM168A,GNAS,ADGRL3,NEU4,TF,OMG,PTPN5,ST8SIA5,CP,NTM,GNE,L1CAM,ST8SIA3,EEF1A2" Drug CID000004877 1NaPP1 Stitch 6.16E-05 1.00E+00 3.43E-03 3.76E-02 5 12 "GRIA1,GRIA2,GRIA4,PIK3CD,LRP8" Drug CID000002207 2-amino-4-phosphonobutyric acid Stitch 6.18E-05 1.00E+00 3.44E-03 3.77E-02 13 91 "ADCY2,RYR1,ADORA1,CACNA1A,CACNA1E,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,EEF1A2" Drug CID000193328 Dimba Stitch 6.53E-05 1.00E+00 3.63E-03 3.98E-02 3 3 "ACHE,DNER,CEP170" Drug 5260_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.73E-05 1.00E+00 3.73E-03 4.09E-02 19 174 "ADD3,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,TMCC2,TTLL7" Drug 5231_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.73E-05 1.00E+00 3.73E-03 4.09E-02 19 174 "ADD3,TUBB4A,HPCAL4,SORBS1,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,VWA5A" Drug CID000005416 krypton Stitch 6.77E-05 1.00E+00 3.74E-03 4.10E-02 7 27 "FGF1,DNER,NHLH1,NODAL,LEFTY2,PMP2,PSD" Drug CID000176265 gacyclidine Stitch 6.79E-05 1.00E+00 3.74E-03 4.11E-02 8 36 "ACHE,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,RTN4" Drug 4430_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.83E-05 1.00E+00 3.75E-03 4.11E-02 20 189 "GRAMD1B,FOXRED2,NTNG1,BCAS1,MYBPC1,GAD2,NCDN,AJAP1,BTRC,HAP1,PDE4B,ZMYND8,PLCH2,EDRF1,PTAFR,PTCH1,PARP11,DSCAM,RASGRF1,DTNA" Drug 3823_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.83E-05 1.00E+00 3.75E-03 4.11E-02 20 189 "ABAT,CEND1,KIAA1109,APC,SLC1A6,ASCL1,CADM3,ADGRB2,RND1,ACSBG1,GLS,VAMP1,PRUNE2,GRIN1,TMEM257,PADI2,TNS1,PRDM2,SMG7,VWA5A" Drug 7438_UP Isotretinoin [4759-48-2]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.83E-05 1.00E+00 3.75E-03 4.11E-02 20 189 "SERPINA3,MBP,PAQR6,APC,SYBU,SNAP25,B4GALNT1,RND1,VAMP1,SEMA4A,GNG3,OPCML,PFKFB3,KLK6,HP1BP3,NAV2,RAB3IL1,ATG16L1,RAP1GAP,ATN1" Drug CID000000224 AMP group Stitch 6.96E-05 1.00E+00 3.81E-03 4.18E-02 43 579 "RPL38,ADAR,ADARB2,ADCY2,ADCYAP1R1,ADORA1,ADORA3,SEMA6A,APC,DGKZ,GPAM,DGKD,SLCO1A2,CAB39,NMNAT2,NCAM1,ADHFE1,ACSBG1,GNAS,CNDP1,ACSL6,NPPA,P2RX7,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CPT1C,FADS2,P2RY12,PRKAB2,PRKACB,PRKCG,PKN2,PRKCZ,CTNND1,MASP1,PTHLH,AK5,KCNMA1,PYGM,RET" Drug CID000004820 pilsicainide Stitch 6.98E-05 1.00E+00 3.82E-03 4.19E-02 9 46 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1,CHRNB2" Drug CID000003676 lidocaine Stitch 7.04E-05 1.00E+00 3.84E-03 4.21E-02 18 160 "ASIC1,ADCY2,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,KCNK10,ASIC3,PHKG1,UBTF,PRKCG,PKN2,PRKCZ,DPYSL5,KCNK1,RET" Drug CID000065065 N-acetyl-L-aspartate Stitch 7.09E-05 1.00E+00 3.86E-03 4.24E-02 14 105 "MAPT,MBP,SCN3A,MOG,FOLH1,MTR,ATP1A2,GFAP,MLC1,CACNA1A,GRM3,NCAN,ACY3,ATN1" Drug CID000115114 DCG-IV Stitch 7.11E-05 1.00E+00 3.87E-03 4.24E-02 11 68 "ADORA1,ADORA3,SLC1A2,SLC1A6,GAD2,CACNA1A,CACNA1E,GRIA2,GRIA4,GRM3,SLC17A6" Drug 1971_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 7.35E-05 1.00E+00 3.99E-03 4.37E-02 20 190 "ADD3,TESK2,ITSN1,CCDC88A,FYN,ZCCHC24,KIF1B,RGL1,GLS,ZEB1,NRGN,DNAJC12,FEZ1,PKN2,RABGAP1L,RAP1GAP,BSDC1,EFNA3,ABI2,LPAR6" Drug 5623_UP Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.35E-05 1.00E+00 3.99E-03 4.37E-02 20 190 "ASIC1,TUBB4A,ANK1,DOCK10,KIF21B,RND1,WSCD1,PAX6,SEZ6L,ASIC3,VAV2,CNTN1,IFFO1,CRMP1,VCAN,PHYHIP,MAGI2,PTPRD,NTM,TMCC2" Drug CID000000765 9-beta-D-arabinofuranosylguanine Stitch 7.41E-05 1.00E+00 4.01E-03 4.40E-02 57 845 "MAPT,SYT9,ADAR,ADARB2,ADCY2,ADORA1,ADORA3,TUBB4A,AGT,ACTL6B,FOXG1,APBB1,ARFGAP2,PDE8B,SNAP25,GFAP,RND1,ARHGEF7,GNAS,GNG3,GOLGB1,GPM6A,CACNA1E,NPPA,NUCB1,NUMA1,GRIA2,GRM3,OMG,CCKBR,GUCY1A2,GUCY1A1,AIFM1,ZFP91,CDC42,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,VAV2,RGS6,PRKACB,PRKCG,PRKCZ,PLPPR5,TUBB2B,PARD6A,KCNMA1,PYGM,DNM2,RGS7,EEF1A2,ROM1,BSCL2" Drug CID006419759 K00077 Stitch 7.61E-05 1.00E+00 4.11E-03 4.51E-02 22 221 "MBP,RTKN,FGF1,NFASC,GFRA1,DDR1,GRIA1,GRIA4,ZFP91,TNFRSF1B,TPM3,TPM4,PIK3CD,PTPA,PRKACB,PRKCG,PRKCZ,MAPK8,MAPK10,STMN4,RET,ELAVL3" Drug ctd:D015124 8-Bromo Cyclic Adenosine Monophosphate CTD 7.62E-05 1.00E+00 4.11E-03 4.51E-02 49 693 "MAPT,SYT9,LGR4,RXRG,AGT,SESN3,APC,CCDC80,TACC2,SLC6A9,DACH2,SOX5,NEK6,DNER,NAP1L2,LMO3,SMOC1,GFAP,KIRREL3,NPPA,GRIA1,ADAMTS8,OMG,AIFM1,REPS2,PTGDR2,PDE1A,PDE2A,ADGRG1,SCRG1,HPCA,CADM1,SULT4A1,ETNPPL,SF1,PHACTR3,ARHGEF4,MAPK10,PMEPA1,PTHLH,CADM2,CNIH3,PTPRE,PTPRZ1,CCDC3,KLRC2,PID1,KLRC3,CALN1" Drug ctd:D015034 Zinc Oxide CTD 7.80E-05 1.00E+00 4.20E-03 4.61E-02 28 318 "MAPT,ADCYAP1R1,AMER2,UNC79,SH3GL2,GPAM,SYBU,MSR1,LRRC55,TAGLN3,SNAP25,CPLX2,NCAM1,INKA2,SEPT3,SYT4,OPCML,CDC42,TNR,SEZ6L,PCSK2,PDE4B,LRTM2,CHGA,FTO,DLG2,RET,EEF1A2" Drug 992_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 7.86E-05 1.00E+00 4.23E-03 4.64E-02 19 176 "ADD3,PPM1E,SYBU,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,NAV2,EFNA3" Drug CID005289517 thio-ATPA Stitch 7.89E-05 1.00E+00 4.23E-03 4.64E-02 4 7 "GRIA1,GRIA2,GRIA4,GRM3" Drug 4302_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.91E-05 1.00E+00 4.24E-03 4.65E-02 20 191 "ABAT,F3,SH3GL2,SORBS1,TAGLN3,ALDH4A1,FYN,ADGRB2,RGL1,RND1,GLS,VAMP1,NRGN,PDE2A,PDE3B,PIK3CD,RIMS3,PLPPR4,SRGAP3,VWA5A" Drug CID000003455 GBR 12909 Stitch 8.15E-05 1.00E+00 4.36E-03 4.79E-02 11 69 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,FOXM1,BCO1,SCN3B,TCF12,PDYN,ASIC3" Drug ctd:D010862 Pilocarpine CTD 8.23E-05 1.00E+00 4.40E-03 4.82E-02 26 286 "ASIC1,ACHE,ADORA1,ANK3,AQP4,GAD2,CACNA1A,GRIA1,GRIA2,GRIK2,GRIN1,GRM3,PTPN5,P2RX7,TJP1,TNR,CHRM1,CHRM4,PRKCG,PRKCZ,MAPK8,PTPRZ1,KCNMA1,KCNN3,RET,EFNA3" Drug 2462_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.48E-05 1.00E+00 4.51E-03 4.94E-02 19 177 "ABAT,TMEM156,ASRGL1,DOCK10,GAS7,EIF4G3,GART,GLS,P2RX7,TNS1,PDE3B,FADS2,NSD2,PPP2R5C,PPP3CB,FEZ1,SIRPA,PTPRE,RPRD1A" Drug 5238_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.51E-05 1.00E+00 4.51E-03 4.94E-02 20 192 "MAPT,FHL1,APC,SYBU,ASPH,ATP2B2,EMC1,INKA2,RGL1,NEUROD1,ROBO3,WWC1,USP2,GUCY1A2,TPD52,SERPINE2,SDC3,PTHLH,KCNK2,RET" Drug 1284_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.51E-05 1.00E+00 4.51E-03 4.94E-02 20 192 "EPS8,ITSN1,APC,PALLD,WDTC1,NCAM1,BCL2L2,RGL1,CAMSAP2,ATP13A2,TPD52,ZFYVE9,NMT2,FEZ1,DZIP3,RIMS3,DNAJC6,SV2A,LPAR6,EPB41L2" Drug 6028_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.51E-05 1.00E+00 4.51E-03 4.94E-02 20 192 "MOBP,SELL,AMPH,SLC1A2,SLC1A7,BRINP2,SNAP25,EMC1,NCAM1,COLGALT2,POPDC3,SEMA4A,ATF7,CHI3L2,CAMKV,MICAL1,ELMO1,KCNC1,KCNJ4,RASGRP2" Drug 2146_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.51E-05 1.00E+00 4.51E-03 4.94E-02 20 192 "ACTN2,FOXRED2,KIAA1109,HPCAL4,FOXG1,APC,BCO1,PALLD,ALDH1L1,RND1,SLCO1C1,VAMP1,CAMSAP2,GPM6B,GPR19,PSD3,ATP13A2,TPM3,SERPINE2,LRRC23" Drug CID000005546 triamterene Stitch 8.65E-05 1.00E+00 4.57E-03 5.02E-02 10 58 "ASIC1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SLC14A1,SCN3B,CA14,ASIC3" Drug CID000007360 tetrahydrofurfuryl alcohol Stitch 8.72E-05 1.00E+00 4.60E-03 5.04E-02 7 28 "ADCY2,FOLH1,ALDH4A1,GART,ADHFE1,HRH3,PTHLH" Drug CID000007175 paraben Stitch 8.72E-05 1.00E+00 4.60E-03 5.04E-02 7 28 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug CID000001986 acetazolamide Stitch 8.73E-05 1.00E+00 4.60E-03 5.04E-02 14 107 "F3,GLS,CACNA1A,RBFOX2,CA14,SLC22A6,CTNND1,PTCH1,KCNA1,KCNA2,KCNA4,KCNA6,KCNK1,KCNK2" Drug CID000000892 myo-inositol Stitch 8.87E-05 1.00E+00 4.66E-03 5.11E-02 55 812 "RPL38,MBP,ADCY2,ADCYAP1R1,RYR1,ADORA1,ADORA3,FCGR1A,AGT,FGF1,FOXM1,AMPH,RASA3,DGKZ,DGKD,B3GAT1,FYN,ATP2B2,GFRA1,GNAS,GNG3,CACNA1A,CACNA1E,CACNB2,GRM3,OPCML,CCKBR,P2RX7,HRH3,PDE3B,NTSR2,CHRM1,PLEKHB1,PIK3CD,P2RY12,ETNPPL,CRLS1,RGS6,PRKACB,CALY,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PLPPR5,PTAFR,PTHLH,DNM2,RGS7,RGS10,CACNG7,LPAR6,BSCL2,EPB41L1" Drug 4788_UP Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.14E-05 1.00E+00 4.76E-03 5.22E-02 20 193 "EMID1,ACTN2,GAS7,RPH3A,SLN,BRINP2,B3GAT1,RND1,GLS,GPM6A,NUMA1,TGFBR3,TNS1,ASIC3,PLEKHB1,CHD1L,RIMS3,PTPRE,KCNMA1,NAV2" Drug 4276_UP Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.14E-05 1.00E+00 4.76E-03 5.22E-02 20 193 "SYNDIG1,MOBP,PKP4,APC,BCAN,SLC6A9,ASCL1,BRINP2,GFRA1,GLS,ADGRL3,GPR17,CHI3L2,SULT4A1,RGS6,CTNND2,RIMS3,NTM,RAD52,DTNA" Drug 5268_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.14E-05 1.00E+00 4.76E-03 5.22E-02 20 193 "MDM4,KIAA1109,FOXG1,APC,RPH3A,SLC1A7,KIF21B,PHLDB1,TCF7L2,USP2,SF1,CRMP1,PRKAB2,SDC3,PKN2,SMG7,TMCC2,ATN1,ELAVL3,LRRC23" Drug 873_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.15E-05 1.00E+00 4.76E-03 5.22E-02 19 178 "ADD3,TUBB4A,SYBU,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3,RASGRP2" Drug CID000003337 fenfluramine Stitch 9.15E-05 1.00E+00 4.76E-03 5.22E-02 19 178 "ASIC1,ADAR,SCN3A,SCN4B,SCNN1D,ASIC4,FGR,LRRC4C,SCN3B,SOX10,GAD2,ZFP91,PDYN,ASIC3,CHRM1,TUB,FTO,PLPPR5,DNAH9" Drug 5693_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.15E-05 1.00E+00 4.76E-03 5.22E-02 19 178 "ADD3,TUBB4A,FHL1,HPCAL4,SORBS1,PKNOX2,FYN,RGL1,RND1,ACSBG1,GLS,VAMP1,PIK3CD,DNAJC12,RIMS3,DNAJC6,MAGI2,EFNA3,VWA5A" Drug CID004346372 AC1N8N2J Stitch 9.32E-05 1.00E+00 4.83E-03 5.30E-02 6 20 "GRIA1,GRIA2,GRIA4,GRIK4,GRM3,PTCH1" Drug CID000003688 IDRA 21 Stitch 9.32E-05 1.00E+00 4.83E-03 5.30E-02 6 20 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug CID006603977 Psora-4 Stitch 9.68E-05 1.00E+00 5.01E-03 5.49E-02 5 13 "KCNA1,KCNA2,KCNA4,KCNC1,KCNN3" Drug CID000126323 1-methylisoguanosine Stitch 9.68E-05 1.00E+00 5.01E-03 5.49E-02 5 13 "ADAR,ADARB2,ADORA1,ADORA3,GPR162" Drug ctd:C540355 1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one CTD 9.70E-05 1.00E+00 5.01E-03 5.49E-02 31 373 "RIMKLA,F3,ADARB2,PPM1E,RPH3A,SLC8A3,CADPS,ALDH4A1,PALLD,GAD2,NEK6,NAP1L2,ACSBG1,GLS,CAMTA1,DDR2,GRIK3,GPR88,DAAM2,TNS1,LGI1,TPM4,NXPH1,PRKCG,ANKS1B,SYNC,ITGAV,KCNA1,ST8SIA3,ATL1,EEF1A2" Drug 7399_UP Methotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.82E-05 1.00E+00 5.05E-03 5.54E-02 20 194 "TESK2,WDTC1,PHLDB1,VAMP1,GNG3,KLHL4,CACNA1A,GRIN1,REPS2,PTGDR2,PMP2,SDC3,CTNND2,PROX1,RAB5B,RAP1GAP,ARHGEF10L,SIDT2,EFNA3,LRRC23" Drug 3811_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.82E-05 1.00E+00 5.05E-03 5.54E-02 20 194 "TTYH1,ASIC1,SYNDIG1,KLRC4,FABP7,GAS7,SOX10,MLC1,MYRF,GPR17,GRIN1,PDE2A,ZMYND8,ZFYVE9,CTNND2,SMG7,ATN1,DSCAM,LMO1,VWA5A" Drug 428_DN 17-AAG; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 9.82E-05 1.00E+00 5.05E-03 5.54E-02 20 194 "RBM10,TUBB4A,CDC42BPA,SLC2A5,WDTC1,NMNAT2,ADAM15,HAP1,TMPRSS5,UBTF,CCSER2,VAV2,NSD2,SMG7,DLG3,RAP1GAP,DSCAM,RET,SIDT2,EPB41L2" Drug CID000028558 L-BMAA Stitch 1.02E-04 1.00E+00 5.23E-03 5.74E-02 8 38 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000068736 CGS 19755 Stitch 1.02E-04 1.00E+00 5.23E-03 5.74E-02 8 38 "SLC6A9,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3" Drug CID000002218 aprindine Stitch 1.02E-04 1.00E+00 5.23E-03 5.74E-02 8 38 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SLC8A2,SCN3B,ASIC3" Drug CID000000342 m-cresol Stitch 1.04E-04 1.00E+00 5.31E-03 5.82E-02 12 83 "MAG,ACER3,F3,CACNA1A,GRIA1,GRIA2,GRIA4,OMG,DCLK1,TPM3,TPM4,ATN1" Drug 4366_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "NDRG2,ASCL1,GFAP,POPDC3,GNG4,GPM6B,HRH3,HPSE2,CHI3L2,PIK3CD,CNTN1,ETNPPL,MICAL2,PTAFR,KCNC1,PTPRZ1,KCNK2,RAD52,RASGRF1,EN2" Drug 3028_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "ST8SIA1,SLC6A9,ASCL1,ATP1A3,PALLD,DKK3,CAMK2A,BRSK2,ADAMTS8,CDH10,SEZ6L,LILRA4,RGS6,PMEPA1,PTHLH,KCNC1,KCND3,KCNH1,RASGRF1,ST8SIA3" Drug CID000220461 NSC3260 Stitch 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "SERPINA3,RYR1,ACTL6B,FOLH1,ANXA7,MSR1,ATP2B2,ADAM15,RND1,MLC1,GRIA1,GRIA2,GRIA4,TPM3,TPM4,TMEFF2,SERPINE2,CHD1L,PRKACB,NUP214" Drug 3737_DN Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "FGF1,MOBP,C1orf61,CGREF1,WDTC1,ADGRB2,PDE3B,PDE4B,ARHGAP22,CADM1,CNTN1,IFFO1,SDC3,CTNND2,CNIH3,SMG7,PID1,DTNA,VWA5A,ELAVL3" Drug 5472_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "PRR5L,PAQR6,FGF1,ANK1,RASA3,CCDC88A,GAD2,COLGALT2,GLS,SEMA4A,ZMYND8,FLRT1,SULT4A1,SPATA6,IGSF1,EDRF1,JAKMIP2,PRDM2,SRGAP3,NAV2" Drug 2132_UP Xylazine [7361-61-7]; Up 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "ACTN2,RYR1,ADORA1,HPCAL4,ANK1,ZNF365,ALDH1L1,VAMP1,CAMSAP2,GPR19,NUMA1,PSD3,ZMYND8,CHI3L2,JAM2,PTAFR,PLPPR1,PARD6A,DSCAM,RAVER2" Drug 3034_UP Capsaicin [404-86-4]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "MAG,CEND1,TUBB4A,SEMA6A,ANK2,APBA2,SLCO1A2,B3GAT1,ALDH4A1,ATP13A2,OPCML,USP2,GUCY1A1,REPS2,NRXN2,VAV2,KCNC1,ARNT2,ELAVL4,EPB41" Drug 4174_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "DPF1,EMID1,KIAA1109,APBA2,APC,GAS7,PKNOX2,ATP2B2,LMO3,SLCO1C1,OPCML,GUCY1A2,ADGRG1,VCAN,PTCH1,ELMO1,HP1BP3,KCND3,KCNMA1,TTLL7" Drug 2225_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-04 1.00E+00 5.31E-03 5.82E-02 20 195 "DPF1,RYR1,KIAA1109,ANK1,PKNOX2,PDE8B,ATP1A2,ATP2B2,CADM3,VAMP1,ZMYND8,HPSE2,POU3F4,PTPRO,NTM,KCNJ4,KCNMA1,DNAH9,RAD52,ATN1" Drug CID000001209 L-quisqualic acid Stitch 1.06E-04 1.00E+00 5.31E-03 5.82E-02 19 180 "ACHE,MBP,ADCY2,TUBB4A,FOLH1,GAD2,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,OMG,PDYN,CHRM1,TUBB2B" Drug 7236_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 5.31E-03 5.82E-02 19 180 "ADD3,SYBU,CCDC88A,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,VAMP1,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,JAKMIP2,TTLL7,EFNA3" Drug 6064_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 5.31E-03 5.82E-02 19 180 "DPF1,ADD3,TUBB4A,SORBS1,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 5950_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 5.31E-03 5.82E-02 19 180 "ABAT,MAPT,TESK2,SH3GL2,SORBS1,FYN,RGL1,RND1,GLS,VAMP1,PADI2,PCDH9,PIK3CD,NMT2,DNAJC12,NOS1AP,RGS10,SIDT2,EFNA3" Drug 3510_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 5.31E-03 5.82E-02 19 180 "DPF1,ADD3,KIAA1109,PPM1E,SYBU,BCO1,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,PIK3CD,DNAJC12,NOS1AP,KIAA0513,TMCC2,EFNA3,RASGRP2" Drug ctd:C029297 vinylidene chloride CTD 1.11E-04 1.00E+00 5.39E-03 5.91E-02 88 1485 "SERPINA3,ABAT,PRR5L,LGR4,NDRG2,F3,ADD3,CDC7,FABP7,FCGR1A,CHST15,SCN4B,FGF1,C1QTNF4,FGR,FOXM1,ASRGL1,CDC42BPA,ANK2,ANK3,RASA3,DOCK10,SESN3,CACHD1,ST8SIA1,CLSTN1,AQP4,MSRA,ALDH4A1,ATP2B2,TNIK,NEK6,ALDH1L1,GFRA1,RGL1,ADHFE1,NFIA,GLS,C1QC,PSRC1,CNDP1,GPM6A,VSTM2A,PSD3,MFSD2A,P2RX7,TNFRSF1B,REPS2,TNS1,TPM4,PDE1A,CA14,PFKFB3,PLEKHB1,MS4A7,SLC22A6,CADM1,ANLN,FADS2,DNAJC12,CNTN1,MICAL1,P2RY12,CP,PNKD,ATRNL1,PRKCZ,MASP1,ACY3,SIRPA,DNAJC6,CEP170,PTPRE,PTPRO,KCNJ10,KCNK1,RAP1GAP,FAM13C,BEND5,L1CAM,SLC6A15,RGS10,ATL1,SFXN5,SSPN,SH3GLB1,PLEKHO1,RCAN2" Drug CID005462126 AC1NUW3V Stitch 1.11E-04 1.00E+00 5.39E-03 5.91E-02 7 29 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3" Drug CID000013296 4-ethylsulfonylnaphthalene-1-sulfonamide Stitch 1.12E-04 1.00E+00 5.39E-03 5.91E-02 15 123 "ASCL1,B3GAT1,SOX10,GFAP,GFRA1,GNAS,TNFRSF1B,TNS1,ACOT7,CRMP1,MED24,PARD6A,SLC17A6,RET,ELAVL3" Drug CID000000424 aspartate Stitch 1.12E-04 1.00E+00 5.39E-03 5.91E-02 39 518 "ABAT,MAPT,ACLY,SLC25A25,ADORA1,SEMA6A,ASRGL1,FOLH1,SLC1A2,SLC1A6,SLC1A7,SNAP25,GAD2,ALDH1L1,GFAP,ADHFE1,GLS,SYT4,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,CYB561A3,GRM3,OMG,CCKBR,PTPN5,PC,TPM3,ETNPPL,PPP2R5C,ACY3,PSMD13,STMN4,SLC17A6,SLC25A18,ABI1,RET" Drug CID006398444 AC1O4QI2 Stitch 1.12E-04 1.00E+00 5.39E-03 5.91E-02 16 137 "MAG,FCGR1A,MOBP,MOG,GRIA1,GRIA2,GRIA4,OMG,TNFRSF1B,TPM3,TPM4,CADM1,RBPJ,KCNJ4,RTN4,RET" Drug 5226_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "SEMA6A,ANK2,DGKD,RPH3A,ASPH,ZCCHC24,PHLDB1,CACNA1A,USP2,CDH8,CHRNB2,SERPINE2,SULT4A1,MICAL1,ATRNL1,SDC3,SRGAP3,RAB3IL1,RALGDS,RASGRP2" Drug 6039_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "MBP,SYNDIG1,KCNIP2,TUBB4A,AMPH,GAS7,SORCS3,SNAP25,WDTC1,ZCCHC24,GPR162,GRIK2,INA,NECAB2,CHD5,SDC3,MASP1,CA10,KCND3,KCNJ4" Drug 3506_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "MDM4,ASIC4,FHL1,SELL,APBA2,SLC1A7,BCO1,ATP2B2,ZCCHC24,GLS,KAZN,NPPA,P2RX7,PAH,DAAM2,MAPK10,PTCH1,JAKMIP2,ELMO1,TMCC2" Drug 2290_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "RYR1,TUBB4A,KIAA1109,ASIC4,APC,GAS7,SNAP25,SPART,AJAP1,PRUNE2,ZEB1,TNS1,SULT4A1,VAV2,CRMP1,RIMS3,PTAFR,PTHLH,KCNMA1,ELAVL3" Drug 4257_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "TTYH1,ABAT,MOBP,ANK1,ASCL1,B3GALT2,INKA2,SLCO1C1,KAZN,BRSK2,PRMT8,HAPLN2,ADGRG1,HPCA,SLC22A6,KCNA2,KCNC1,CAMK1G,USH1C,RGR" Drug 3042_UP Carbachol [51-83-2]; Up 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "ABAT,ACHE,ADORA3,C1orf61,ASCL1,ALDH4A1,TCF7L2,USP2,INA,GUCY1A1,PTGDR2,SCRG1,VAV2,PRRX1,RGS6,ZBTB16,STMN4,KCNK1,PID1,ROM1" Drug 5769_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "MAPT,GRAMD1B,KIAA1109,FOXG1,ANK2,PPM1E,ADGRB2,NEUROD1,VAMP1,BTRC,PADI2,MAGI1,PDE2A,MAPK8,RIMS3,PTHLH,RAD52,DTNA,SEC61A2,EPB41" Drug 5259_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "NDRG2,ADORA1,MOBP,FOXG1,C1orf61,CDC42BPA,GAD2,RND1,VAMP1,PTGDR2,NRXN1,SULT4A1,CRMP1,SNCAIP,PTHLH,AK5,PID1,ATG16L1,ATN1,ST8SIA3" Drug 412_DN tetraethylenepentamine pentahydrochloride; Down 200; 100uM; HL60; HG-U133A Broad Institute CMAP Down 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "NDRG2,ANK2,PDE8B,SNAP25,ALDH1L1,VAMP1,GNG3,OMG,PADI2,CA14,CHRNB2,CAMKV,CNTN1,PACSIN1,ECE2,MASP1,ITIH2,NUP214,ABI2,ELAVL4" Drug 6063_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "CEND1,GAS7,SNAP25,ZSWIM8,ALDH1L1,KCNK10,SEZ6L,HPSE2,CHI3L2,MICAL1,SPATA6,PROX1,ITIH2,PRDM2,PTPRO,KCNMA1,ATN1,RASGRF1,ST8SIA3,RGR" Drug 3700_UP Merbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "ANK1,PKNOX2,ATP1A3,CADM3,NEUROD1,GNAS,ADGRL3,GRIK2,GRIN1,USP2,TNS1,PCDH9,CHI3L2,CAMKV,IGSF1,CTNND2,MAPK8,RASGRF1,NUP214,RASGRP2" Drug 3890_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "DPF1,NLGN4X,PLA2G6,FOXG1,SORCS3,CPLX2,NPAS3,INKA2,ACSBG1,OMG,CELF3,CDC42,PCDH9,HRH3,CNTN1,SNCAIP,ATRNL1,PTAFR,KCNA2,VWA5A" Drug 4991_UP Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "FABP7,AGT,ANK3,APC,GAS7,SYBU,RPH3A,SLC2A5,PDE8B,ALDH1L1,NEUROD1,GNAS,PRUNE2,USP2,KCNK10,CDH10,SULT4A1,KCND3,NTM,ATN1" Drug 3668_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "KIAA1109,HPCAL4,GAS7,BCAN,NFASC,GFAP,AJAP1,NEURL1,TNS1,DCLK1,PDE2A,PDE3B,CHI3L2,PIK3CD,CTNND2,RIMS3,NKAIN1,RAD52,RGS7,RAVER2" Drug 4357_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "KLRC4,NLGN4X,AGT,ANK1,APC,SLC2A5,MSR1,TNIK,GAD2,ZSWIM8,WSCD1,GPM6A,INA,PCDH9,MAPK8,NOS1AP,PTAFR,PID1,ATN1,FAM13C" Drug 3070_UP Metyrapone [54-36-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "CEND1,MOBP,C1orf61,RASA3,NCAM1,ALDH1L1,SLCO1C1,GNG4,GPM6B,ATF7,NPPA,SPX,INA,GUCY1A2,ZFYVE9,ST8SIA5,ARHGEF4,KIAA0513,PTPRZ1,EFNA3" Drug 5669_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "CEND1,PLA2G6,AMPH,APBA2,BCO1,GAD2,MYH7,NEUROD1,RND1,VAMP1,CDK5R2,CAMK2A,NUMA1,OMG,PTGDR2,PMP2,VCAN,PTPRD,DSCAM,VWA5A" Drug 2236_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "KIAA1109,MOBP,RASA3,DOCK10,GAS7,DLL3,FYN,ALDH1L1,VAMP1,GNG3,BTRC,NUMA1,GRIK2,TNS1,PTGDR2,GPR37L1,SULT4A1,PACSIN1,RABGAP1L,RAD52" Drug 2958_UP Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "FHL1,CDC42BPA,RASA3,SHANK2,PALLD,TNIK,ALDH1L1,WWC1,PADI2,TNS1,RBFOX2,ZFYVE9,UBTF,VAV2,OSBPL3,PTAFR,SMG7,RAP1GAP,BEND5,RASGRP2" Drug 6000_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "WLS,ADORA1,ASIC4,CDC42BPA,RASA3,APC,PKNOX2,ZCCHC24,GLS,VAMP1,POPDC3,PRUNE2,INA,PDE3B,MAGI2,PARD6A,RAB3IL1,DTNA,SLC6A15,NUP214" Drug 5073_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "TTYH1,EMID1,PAQR6,EXTL1,PLA2G6,AMPH,NTNG1,PDE4B,CHGA,CAMKV,CABP1,PACSIN1,NOS1AP,PROX1,TOX,RIMS3,KCNC1,PID1,FAM13C,ABCC9" Drug 874_UP (-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "EMID1,ANK2,NLGN1,ZNF365,ASPH,DKK3,NRGN,CAMK2A,TGFBR3,TMEM257,PCDH9,PIK3CD,SPATA6,PTHLH,KCND3,RAB3IL1,DSCAM,RASGRF1,RGS10,EFNA3" Drug 4402_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "MAPT,RYR1,FGF1,HPCAL4,SH3GL2,DNAH17,SNAP25,KIF21B,GPR162,MLC1,BRSK2,INA,CAMKV,PIK3CD,POU3F2,PROX1,PHYHIP,PTAFR,FAM13C,LMO1" Drug 3208_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "MBP,ARID1A,GRAMD1B,CCDC181,ATP2B2,CADM3,SOX10,RND1,BTRC,NPPA,GRIK2,GPR88,SEZ6L,CNTN1,VCAN,PTAFR,PRDM2,KCNC1,ST8SIA3,VWA5A" Drug 3132_UP THIP Hydrochloride; Up 200; 22.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "ABAT,SYNDIG1,FOXRED2,MOBP,FOXG1,ANK3,APBA2,EMC1,SPART,ATF7,OMG,HRH3,SCRG1,CHRM4,CNTN1,NCAN,PTCH1,DLG3,TTLL7,ROM1" Drug 4490_UP Piretanide [55837-27-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "EMID1,FOXG1,BCAS1,SHANK2,ATM,FYN,ATP2B2,TNIK,CADM3,NPAS3,SEMA4A,GPM6A,ATF7,OMG,CHRNB2,SPATA6,PKN2,NOS1AP,ITIH2,SMG7" Drug 4100_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.13E-04 1.00E+00 5.39E-03 5.91E-02 20 196 "ASIC1,SELL,CDC42BPA,APC,SLN,ASTN1,ATM,ATP1A3,ACSBG1,MYRF,ZMYND8,PLEKHB1,PRDM2,STMN4,SMG7,RALGDS,ATN1,ST8SIA3,ARHGEF10L,LRRC23" Drug 5802_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.14E-04 1.00E+00 5.43E-03 5.96E-02 19 181 "ABAT,SORBS1,TAGLN3,BRINP2,FYN,ADGRB2,RGL1,RND1,GLS,TGFBR3,NEURL1,PCDH9,DNAJC12,PTCH1,DNAJC6,JAKMIP2,PLPPR4,EFNA3,VWA5A" Drug 5822_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.14E-04 1.00E+00 5.43E-03 5.96E-02 19 181 "ABAT,MAPT,TESK2,TAGLN3,FYN,PALLD,ZCCHC24,RGL1,GLS,VAMP1,REPS2,PCDH9,SERPINE2,DNAJC12,VCAN,DNAJC6,PLPPR4,PID1,EFNA3" Drug CID005360525 fluorine atom Stitch 1.17E-04 1.00E+00 5.51E-03 6.04E-02 9 49 "ABAT,MAP6,F3,ADORA3,ADGRB2,HRH3,FTO,PMP2,RCAN2" Drug CID000005087 Ro-1724 Stitch 1.18E-04 1.00E+00 5.51E-03 6.04E-02 14 110 "ADAR,ADARB2,ADORA1,ADORA3,ACTL6B,PDE8B,NAP1L2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PRKACB,KCNMA1" Drug CID000457707 AC1L9X2P Stitch 1.21E-04 1.00E+00 5.51E-03 6.04E-02 11 72 "MAG,MOBP,MOG,SELL,FOLH1,ST8SIA1,CCDC88A,B4GALNT1,NCAM1,NEU4,OMG" Drug 4715_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ADCY2,PDE8B,ATM,WDTC1,EMC1,NCAM1,PHLDB1,NEURL1,CDH8,MAGI1,ZMYND8,HPSE2,PMP2,RGS6,MAPK10,PHYHIP,SMG7,NKAIN1,CAMK1G,NUP214" Drug 6803_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "EMID1,AGT,FHL1,HPCAL4,GPR153,DLL3,ATP2B2,WDTC1,INKA2,CDK5R2,SPX,ADGRG1,NCAN,SYNC,ITIH2,CNIH3,PARD6A,RAB3IL1,FAM13C,RGS10" Drug 5054_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "SLN,ATP2B2,SOX10,ADGRB2,NCAM1,PHLDB1,ADGRL3,CACNA1A,GPR17,NUMA1,BRSK2,GUCY1A2,PTGDR2,HPSE2,VCAN,ITIH2,SRGAP3,ARNT2,PID1,LRRC23" Drug 2151_UP Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "FHL1,FOXG1,AMPH,ANK1,SLC1A7,GPR153,PALLD,CADM3,GPM6B,TCF7L2,GRIA4,OMG,REPS2,PADI2,TPD52,MAGI1,PDE1C,EDRF1,DLG3,EEF1A2" Drug 3740_DN Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "FOXRED2,FGF1,MOBP,SELL,SLC14A1,ADGRB2,TNS1,PDE3B,ASIC3,CHRNB2,CADM1,KIAA1549L,IFFO1,ARHGEF4,CTNND2,PTCH1,KCNMA1,RAB3IL1,SUSD4,RGS10" Drug 6840_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "CEND1,HPCAL4,AQP4,RPH3A,GPR153,RND1,GNG3,CACNA1A,PDE1C,ADGRG1,PACSIN1,CRMP1,MICAL2,MAGI2,KCNJ4,KCNMA1,NUP214,ST8SIA3,ELAVL3,LRRC23" Drug 4604_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "C1orf61,NLGN1,SLC1A6,MSR1,ASCL1,SNAP25,GLS,GNG4,GRIN1,ADAMTS8,OPCML,P2RX7,CABP1,POU3F2,VCAN,NOS1AP,KCNA2,PLPPR4,KCNC1,EN2" Drug 4736_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ASIC1,RYR1,FHL1,NLGN1,BCO1,BRINP2,ATP1A2,ATP2B2,NCAM1,POPDC3,GRIA1,TMEM257,CDH8,CHGA,HPCA,KCNMA1,ATN1,ELAVL3,LRRC23,RASGRP2" Drug 6060_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "WLS,NDRG2,SEMA6A,FHL1,FOXG1,CDC42BPA,SLC1A7,ALDH4A1,PHLDB1,RND1,CHRNB2,ATRNL1,VCAN,PRKAB2,GON4L,MAGI2,PEX5,DNM2,RAD52,EFNA3" Drug 5796_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "DPF1,ADCY2,KIAA1109,FGF1,FGR,ANK1,CADM3,SOX10,MYRF,NEURL1,PADI2,PDE2A,ZMYND8,TMPRSS5,CHI3L2,CAMKV,PLPPR1,NTM,RABGAP1L,RAB3IL1" Drug 3011_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ARID1A,ADCY2,AMPH,CDC42BPA,SLN,CCDC181,TNIK,GAD2,HAP1,NUMA1,USP2,TPM3,JAM2,ZFYVE9,SULT4A1,COL9A2,CTNND2,PMEPA1,MAGI2,BEND5" Drug 335_UP nifedipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "EMID1,FOXRED2,FGR,CDC42BPA,ANK1,ANK2,RASA3,APBB1,KIAA1614,SLC1A7,ZCCHC24,NRGN,RBFOX2,CHD5,CALY,MASP1,KCNMA1,L1CAM,RGR,SIDT2" Drug 5823_UP Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ABAT,MAPT,C1orf61,APC,RPH3A,SLCO1A2,TAGLN3,ATP2B2,GART,GNAS,WWC1,GPM6B,VAV2,PACSIN1,CHD5,CNIH3,RABGAP1L,RASGRF1,RGS10,LRRC23" Drug 7217_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "KIAA1109,FHL1,C1orf61,APBA2,GAS7,SYBU,WDTC1,NPAS3,NDUFA5,GLS,GNAS,OPCML,TPD52,PDE3B,DUSP26,VAV2,DPP6,VWA5A,LRRC23,RASGRP2" Drug 6241_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "PAQR6,FHL1,SYBU,RPH3A,RND1,SEMA4A,WSCD1,ATP13A2,GUCY1A2,TPD52,ADGRG1,HPSE2,NMT2,MICAL1,RGS6,SDC3,SYNC,KIF2A,ATN1,GNE" Drug 6041_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "CEND1,TUBB4A,FHL1,SLC1A7,ASCL1,SNAP25,FGF17,PRUNE2,OPCML,GUCY1A1,HRH3,LILRA4,ADGRG1,MICAL1,TOX,PRDM2,KCNC1,PTPRO,KCND3,KCNMA1" Drug 5627_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "CEND1,ADORA3,PLA2G6,MOBP,CDC42BPA,SLC1A7,SLCO1A2,KIF21B,SLCO1C1,PRUNE2,WSCD1,CCKBR,SEZ6L,VCAN,MAPK10,NOS1AP,PTAFR,SMG7,SLC17A6,VWA5A" Drug 3686_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "NDRG2,SLC1A6,NFASC,ALDH1L1,NHLH1,PRUNE2,GRIK2,OMG,USP2,MAGI1,PDE2A,CHI3L2,CHRNB2,PIK3CD,POU3F4,MAPK8,EDRF1,RIMS3,PRDM2,RAVER2" Drug 5088_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ACHE,PAQR6,CEND1,ADORA1,BBOX1,SORBS1,DNAH17,SOX10,GPM6B,HAP1,BRSK2,PTGDR2,PMP2,RGS6,MASP1,ITIH2,KCNMA1,DSCAM,ABCC9,RGR" Drug 4640_DN Domperidone maleate; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "FOXRED2,KIAA1109,FGF1,MOBP,ASTN1,CADM3,MYH7,ASTN2,BTRC,GPM6B,GPR17,CDC42,CABP1,DZIP3,KIAA0513,GON4L,PTHLH,RABGAP1L,RGR,RGS10" Drug 5619_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ASIC1,ADORA3,ASCL1,ATP2B2,NPAS3,POPDC3,WSCD1,TF,MICAL2,MAPK8,MAPK10,KCND3,SRGAP3,NTM,KCNJ4,ATN1,RASGRF1,CRTAC1,TTLL7,VWA5A" Drug 5280_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "NDRG2,AGT,CDC42BPA,APC,GPR153,ALDH4A1,ADAM15,NDUFA5,RGL1,GLS,ZFYVE9,NOS1AP,GON4L,PLPPR1,JAKMIP2,PEX5,RAB3IL1,RAD52,DTNA,EN2" Drug 2494_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "AGT,AMPH,BCAN,SLN,ALDH4A1,GPR162,PHLDB1,ACSBG1,WSCD1,ATF7,ATP13A2,GUCY1A2,CDC42,CCSER2,POU3F2,PLPPR1,PRDM2,FAM13C,SSPN,RASGRP2" Drug 427_DN iloprost; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "NDRG2,ADORA3,TUBB4A,SLC2A5,PKNOX2,PDE8B,NMNAT2,ADAM15,ARHGEF7,HAP1,CHRM4,CCSER2,VAV2,CNTN1,MAPK10,ITIH2,DSCAM,SIDT2,VWA5A,EPB41L2" Drug 4075_UP Metrizamide [31112-62-6]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "ACTN2,AGT,SCN3A,AMPH,ANK1,ANK2,GAS7,ZSWIM8,ADGRB2,RND1,GNG4,ADAMTS8,OLR1,USP2,HPSE2,CADM1,IFFO1,SV2A,KCNJ4,RPE65" Drug 5775_UP Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "PRR5L,MDM4,ADORA1,FGF1,BCAS1,EMC1,GNG3,MYRF,GPR17,GRIA4,SEZ6L,PDE3B,STMN4,KCND3,SRGAP3,PID1,DPP6,DSCAM,DTNA,ELAVL3" Drug 4142_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "NDRG2,ADORA1,FOXG1,BCAN,TAGLN3,BRINP2,SNAP25,AJAP1,WSCD1,DAAM2,TNS1,FADS2,CRMP1,VCAN,PRKAB2,SDC3,MAPK8,PLPPR1,KCNMA1,ATN1" Drug 2513_UP Delsoline [509-18-2]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 5.51E-03 6.04E-02 20 197 "BCAR3,MOBP,CDC42BPA,NLGN1,SLCO1A2,ASPH,SORCS3,CADM3,GFRA1,GLS,KAZN,CAMSAP2,CACNA1A,HAP1,OLR1,PCDH9,SEZ6L,PROX1,KCND3,SUSD4" Drug 6879_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-04 1.00E+00 5.56E-03 6.09E-02 19 182 "F3,TUBB4A,PKNOX2,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,NAV2,EFNA3" Drug 1160_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.23E-04 1.00E+00 5.56E-03 6.09E-02 19 182 "PLA2G6,ASIC4,RASA3,ITSN1,PDE8B,TAGLN3,KCNK10,TNS1,PDE4B,CCSER2,SULT4A1,NECAB2,PRKAB2,PRKACB,KLK6,KIAA0513,PTAFR,RGS10,EPB41L2" Drug 3227_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-04 1.00E+00 5.56E-03 6.09E-02 19 182 "ADD3,TUBB4A,PPM1E,SORBS1,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,BTRC,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,NAV2,EFNA3" Drug 5511_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.23E-04 1.00E+00 5.56E-03 6.09E-02 19 182 "ADD3,SORBS1,SYBU,PKNOX2,CCDC88A,FYN,TNIK,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PIK3CD,DNAJC12,RIMS3,DNAJC6,EFNA3,VWA5A" Drug CID000002551 carbachol Stitch 1.24E-04 1.00E+00 5.56E-03 6.09E-02 48 688 "ACHE,ACLY,ADCY2,RYR1,ADORA1,ADORA3,AGT,ACTL6B,FOXM1,B3GAT1,FYN,ATP2B2,MYH7,MLC1,GNAS,GNG3,CACNA1A,CACNA1E,NPPA,CACNB2,GRM3,CCKBR,GUCY1A2,GUCY1A1,PTGDR2,HRH3,PDE1A,PDE2A,PDE3B,CHRM1,CHRNB2,PIK3CD,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PRDM2,KCNC1,KCNJ4,KCNJ9,KCNJ10,KCNMA1,KCNN3,RGS7,CACNG7,BSCL2" Drug CID003035711 DETC-MeSO Stitch 1.24E-04 1.00E+00 5.56E-03 6.09E-02 8 39 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000001232 HA-966 Stitch 1.24E-04 1.00E+00 5.56E-03 6.09E-02 8 39 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TPM3" Drug CID000002890 CX546 Stitch 1.26E-04 1.00E+00 5.56E-03 6.09E-02 6 21 "NELL1,GRIA1,GRIA2,GRIA4,GRIK4,GRM3" Drug CID000128390 AA-2379 Stitch 1.26E-04 1.00E+00 5.56E-03 6.09E-02 6 21 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug 6146_UP Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "RYR1,FGF1,C1orf61,NTNG1,MSR1,ASTN2,MYRF,PRUNE2,WSCD1,HAP1,SEZ6L,CABP1,POU3F4,KLK6,PARD6A,DLG3,RET,USH1C,LRRC23,RASGRP2" Drug 5694_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "BBOX1,MOBP,C1orf61,APBA2,GAS7,SLN,LMO3,PHLDB1,RND1,AJAP1,GLS,VAMP1,PCSK2,FADS2,MAGI2,PTPRO,KCNJ9,ATN1,CAMK1G,RGS7" Drug 388_DN raloxifene hydrochloride; Down 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "TUBB4A,ANK1,AQP4,CADM3,GANAB,BTRC,OMG,CDC42,PDE4B,TMPRSS5,CCSER2,MED1,RGS6,KCNA1,DLG3,PLEKHB2,RALGDS,NUP214,RLBP1,RCAN2" Drug 2173_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "MAPT,CEND1,FOXRED2,FHL1,MSR1,SLC8A2,ALDH4A1,CAMSAP2,USP2,NEURL1,REPS2,TMPRSS5,CHI3L2,FLRT1,POU3F2,MAPK8,EDRF1,PID1,PAK5,RASGRP2" Drug 1532_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,EMID1,MOBP,FOXG1,DGKD,TAGLN3,WDTC1,POPDC3,BTRC,WSCD1,NEURL1,TNR,PCDH9,ZFYVE9,NMT2,CNTN1,NOS1AP,KCNJ4,RAB3IL1,SEC61A2" Drug 5770_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "FGF1,SEMA6A,ASIC4,HPCAL4,SLCO1A2,TAGLN3,MYRF,CDK5R2,GRIN1,GUCY1A2,TNS1,CDH8,MAGI1,ARHGAP22,MAPK8,MAPK10,KCND3,RET,LMO1,LRRC23" Drug 4363_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "MOBP,RPH3A,SLC1A7,SLC6A9,TAGLN3,ALDH1L1,GPR162,VAMP1,WSCD1,CACNB2,CCKBR,CELF3,KCNK10,GPR37L1,SULT4A1,SV2A,ATN1,ST8SIA3,ELAVL3,OLIG2" Drug 7293_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SERPINA3,PAQR6,TESK2,MOBP,DOCK10,RPH3A,SLC1A7,SLC6A9,SHANK2,WDTC1,KAZN,ADGRL3,GUCY1A2,PLEKHB1,IFFO1,SDC3,JAKMIP2,PEX5,ARHGEF10L,SEC61A2" Drug 2108_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,SEMA6A,SELL,DOCK10,SLN,SNAP25,WDTC1,GPR162,NEUROD1,ADGRL3,GPM6A,GRIA1,GRIN1,CDH8,ARHGAP22,IGSF1,PTAFR,NUP214,RGS10,LRRC23" Drug 5993_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "EMID1,MDM4,FGF1,SEMA6A,FHL1,ANK2,RASA3,RPH3A,SHANK2,ATP1A3,KIF21B,CADM3,INKA2,POPDC3,CACNB2,HAP1,NEURL1,PDE3B,MAPK8,CNIH3" Drug 6165_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ADORA1,ANK3,SORBS1,SLC1A7,PDE8B,SLCO1A2,CADM3,GPR162,BTRC,ZEB1,HAP1,TMEM151B,GUCY1A1,SEZ6L,CHI3L2,MICAL2,RIMS3,TMCC2,DSCAM,ELAVL3" Drug 3905_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ARID1A,CDC42BPA,PKNOX2,DLL3,ZCCHC24,GNAS,WSCD1,NPPA,TCF7L2,EML4,DAAM2,TNS1,CDH8,PIK3CD,SULT4A1,PACSIN1,MAPK8,NOS1AP,SYNC,PTHLH" Drug 2725_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SYNDIG1,ACTN2,TUBB4A,SLC1A2,SHANK2,NAP1L2,BTRC,TF,OMG,OPCML,TGFBR3,NEURL1,HRH3,PRMT8,SULT4A1,DZIP3,EDRF1,TMCC2,OLIG2,RASGRP2" Drug 3711_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ADORA1,PLA2G6,HPCAL4,GAS7,PKNOX2,GAD2,NFASC,GNG3,NPPA,GRIK2,OLR1,CDH8,SEZ6L,ZMYND8,SULT4A1,MASP1,PTAFR,PRDM2,KCNJ4,NUP214" Drug 5272_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SYNDIG1,FHL1,CDC42BPA,NLGN1,PKNOX2,GAD2,COLGALT2,TCF7L2,OMG,TNS1,CDH10,CNTN1,SDC3,ITIH2,PTPRD,SRGAP3,KCNK2,KCNMA1,EPB41,RASGRP2" Drug 6099_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,ASIC4,ANK2,SHANK2,PHLDB1,VAMP1,PRUNE2,GPM6A,GPM6B,ATF7,GRIA1,OMG,INA,HRH3,CHD5,VCAN,JAKMIP2,RABGAP1L,ATN1,CAMK1G" Drug 6965_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "MAPT,PAQR6,FHL1,C1orf61,BCAS1,PKNOX2,ACSBG1,GNAS,GNG3,BTRC,PCDH9,PPP2R5C,MAPK8,KIAA0513,KCND3,SRGAP3,DTNA,NUP214,SSPN,SIDT2" Drug 4413_UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,APC2,HPCAL4,ANK1,RASA3,SLN,ATP1A3,GPR162,INKA2,USP2,CELF3,TNS1,SEZ6L,TENM4,MICAL2,ITIH2,KCND3,LMO1,VWA5A,RASGRP2" Drug 4374_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "MAG,EMID1,ACTN2,FABP7,ADORA1,ANK1,TAGLN3,DLL3,ATP2B2,NCAM1,GNG4,GRIK2,PTGDR2,GPR37L1,SULT4A1,ARHGEF4,NOS1AP,DNAJC6,KCND3,DNAH9" Drug 4113_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SYNDIG1,NDRG2,KLRC4,DOCK10,SLC2A5,MSR1,ARPP21,INKA2,RND1,SLCO1C1,OMG,GUCY1A1,CDH10,PTGDR2,CHRNB2,RAB3IL1,ATN1,LMO1,VWA5A,RCAN2" Drug 4425_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,MAPT,CEND1,PLA2G6,SEMA6A,FOXG1,ANK1,ZCCHC24,GPR162,GLS,GPM6A,ATF7,HAP1,CCKBR,KCNK10,TNS1,CDH8,IFFO1,PKN2,TTLL7" Drug 7437_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "EMID1,ARID1A,WLS,TESK2,FHL1,SLC1A7,SCMH1,ADAM15,ALDH1L1,VAMP1,GNG3,WSCD1,ARHGAP19,MICAL1,MICAL2,DNAJC6,PARD6A,RAB3IL1,ATG16L1,ATN1" Drug 3023_UP Iodixanol [92339-11-2]; Up 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ABAT,ANK2,APC,ST8SIA1,ASCL1,ASPH,ALDH4A1,PALLD,ALDH1L1,GLS,OMG,CDH10,HRH3,LILRA4,GPR37L1,CCSER2,TOX,KCNH1,ATG16L1,ST8SIA3" Drug 3710_UP Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "APC2,ANK2,RASA3,AQP4,RPH3A,PDE8B,ATP2B2,ALDH1L1,GPR17,HAP1,P2RX7,SULT4A1,EDRF1,RIMS3,ITIH2,ARNT2,KCNK2,NKAIN1,FAM13C,ST8SIA3" Drug 2537_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "EMID1,KIAA1109,ANK1,SORBS1,PDE8B,ASPH,ALDH4A1,CCDC181,B3GALT2,NCAM1,WSCD1,TCF7L2,HAP1,KCNK10,POU3F2,CRMP1,PROX1,KIAA0513,TMCC2,RAB3IL1" Drug 2387_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "MAPT,FHL1,CDC42BPA,ANK3,APC,GPR153,ALDH4A1,ZCCHC24,GRIN1,ATP13A2,RBFOX2,ZFYVE9,PTPA,CTNND1,NOS1AP,PHYHIP,DLG3,ST8SIA3,LRRC23,RASGRP2" Drug 2890_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "APC2,FOXG1,DOCK10,SLC1A7,SLN,ASTN1,ALDH1L1,NEUROD1,TF,GUCY1A2,CDH10,SEZ6L,PDE4B,CHI3L2,VAV2,PACSIN1,VCAN,PROX1,CRTAC1,ELAVL3" Drug 251_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ASIC1,F3,ANK2,ITSN1,ASCL1,CADM3,NMNAT2,NAP1L2,ARHGAP19,PRMT8,CHRNB2,CNTN1,PTHLH,C1orf109,KCNMA1,DPP6,SIDT2,LPAR6,RCAN2,LRRC23" Drug 6742_UP Carbachol [51-83-2]; Up 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "KIAA1109,FGF1,SEMA6A,FOXG1,SLC1A7,SHANK2,SLCO1A2,NCAM1,ALDH1L1,PRUNE2,TNS1,PCSK2,PDE3B,ZMYND8,PHKG1,KCND3,KCNH1,DSCAM,DTNA,CAMK1G" Drug 3926_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SYNDIG1,ADORA1,SLC30A10,SLC1A7,CCDC88A,FYN,NMNAT2,COLGALT2,GFAP,FGF17,NEUROD1,GNAS,SEZ6L,VAV2,SNCAIP,PTCH1,DNAJC6,DNAH9,ELAVL3,RCAN2" Drug 7018_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "GAS7,TACC2,WDTC1,GAD2,ZSWIM8,PHLDB1,GLS,SEMA4A,CAMSAP2,ATP13A2,FEZ1,KIAA0513,PTAFR,PRDM2,STMN4,TMCC2,DLG3,RALGDS,DTNA,EPB41L2" Drug 2909_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "EMID1,CEND1,ACTN2,AGT,CDC42BPA,SLC8A2,TAGLN3,ALDH1L1,GNG4,OMG,CRB1,PAH,CDH8,DCLK1,PTAFR,DNAJC6,CNIH3,CAB39L,DNM2,RGS10" Drug 3135_UP Alfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "SYNDIG1,ACTN2,C1orf61,GPR153,ASPH,CCDC181,ZCCHC24,ALDH1L1,GNG3,GPM6A,CACNB2,OMG,SEZ6L,ZFYVE9,NECAB2,IGSF1,KLK6,PLPPR1,KCND3,LRRC23" Drug 6383_UP Orlistat; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "DPF1,ACTN2,RPH3A,SLC2A5,PKNOX2,WDTC1,NMNAT2,NEUROD1,AJAP1,GLS,POPDC3,GNG4,TF,CCKBR,PCDH9,CDH10,IFFO1,PTPRO,ATG16L1,EFNA3" Drug 3624_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "ADORA1,KIAA1109,SLC30A10,C1orf61,FYN,GFAP,ACSBG1,NPPA,ZEB1,OPCML,PAH,HPSE2,SULT4A1,PACSIN1,ELMO1,PRDM2,KCND3,SRGAP3,DPP6,RASGRP2" Drug 640_UP paclitaxel; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 5.56E-03 6.09E-02 20 198 "TUBB4A,FOXRED2,ASCL1,GPR153,EIF4G3,FXYD6,COLGALT2,TCF7L2,GRIN1,OPCML,INA,PCDH9,ARHGAP19,CHRM4,FEZ2,PRDM2,ATN1,DSCAM,CAMK1G,EFNA3" Drug 5981_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.32E-04 1.00E+00 5.63E-03 6.18E-02 19 183 "ABAT,TUBB4A,BRINP2,KIF21B,RGL1,RND1,ACSBG1,GLS,USP2,CADM1,NMT2,DNAJC12,SPATA6,CTNND2,PLPPR4,SRGAP3,RASGRF1,EFNA3,RASGRP2" Drug 7550_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.32E-04 1.00E+00 5.63E-03 6.18E-02 19 183 "ADD3,TUBB4A,PPM1E,SYBU,FYN,ZCCHC24,RGL1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,NMT2,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3" Drug 6434_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.32E-04 1.00E+00 5.63E-03 6.18E-02 19 183 "ADD3,TUBB4A,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,VAMP1,PCDH9,RBFOX2,ACOT7,PLEKHB1,PIK3CD,DNAJC12,DNAJC6,EFNA3,RASGRP2" Drug CID000004425 EN-1530 Stitch 1.33E-04 1.00E+00 5.65E-03 6.19E-02 25 278 "ABAT,ACLY,ADCY2,ADORA1,AGT,ACTL6B,FOXM1,ASRGL1,B3GAT1,PRLHR,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,CCKBR,HRH3,PDYN,NTSR2,CHRM1,CHRNB2,SULT4A1,PRKCG" Drug CID000082686 cresyl violet acetate Stitch 1.34E-04 1.00E+00 5.66E-03 6.21E-02 10 61 "ACHE,BCAN,BCO1,GAD2,GFAP,FGF17,NCAN,BLOC1S6,PEX5,ELAVL3" Drug CID000439587 polyproline Stitch 1.36E-04 1.00E+00 5.66E-03 6.21E-02 26 295 "EPS8,ACTL6B,ANXA7,SH3GL2,APBB1,LRRC4C,SHANK2,SNCB,FYN,PALLD,SOX5,ADAM15,PTPN5,CDC42,PCSK2,HNRNPK,MICAL1,PACSIN1,RBPJ,ARHGEF4,CTNND2,PLPPR5,SIRPA,ELMO1,ABI1,YY1AP1" Drug CID000000469 alpha-aminoadipate Stitch 1.38E-04 1.00E+00 5.66E-03 6.21E-02 11 73 "SLC1A2,GART,GFAP,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,SLC22A6,RLBP1" Drug 2683_UP nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ABAT,ASPH,ATP2B2,SOX10,NCAM1,WSCD1,GPM6B,BRSK2,CDC42,CDH10,CHGA,JAM2,VAV2,RGS6,MAPK10,MASP1,KCNN3,RASGRF1,NUP214,OLIG2" Drug 2376_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "SYNDIG1,NDRG2,SEMA6A,FHL1,DNAH17,ALDH4A1,SOX10,GNG4,NUMA1,RBFOX2,TPM3,BEST1,PACSIN1,MAPK10,DNAJC6,NTM,DSCAM,CRTAC1,EEF1A2,RASGRP2" Drug 1605_UP Clopamide [636-54-4]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "NDRG2,PLA2G6,BCAN,PDE8B,SNAP25,CADM3,ADGRB2,ALDH1L1,CACNA1A,NPPA,OMG,LILRA4,DUSP26,CAMKV,CNTN1,PACSIN1,GON4L,TMCC2,NUP214,ARHGEF10L" Drug 2744_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,NDRG2,SEMA6A,FHL1,BCAN,SHANK2,GPR153,GLS,KAZN,HAP1,PSD3,CDC42,CDH10,CHRNB2,FADS2,MAPK8,PRDM2,MAGI2,RAD52,EFNA3" Drug 5856_UP Milrinone [78415-72-2]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "MAPT,PLA2G6,SLC1A7,ACSBG1,KAZN,GPM6B,PSD3,PADI2,PCSK2,CHRNB2,CAMKV,CNTN1,POU3F2,DZIP3,TOX,STMN4,KCNA2,PARD6A,RASGRP2,UEVLD" Drug 7146_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ASIC1,MAPT,PAQR6,F3,TESK2,CDC42BPA,SHANK2,WDTC1,PHLDB1,KAZN,GPM6B,NUMA1,PDE4B,PMP2,EDRF1,SMG7,KCNC1,RAB5B,RALGDS,RGS10" Drug 3101_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,SLC30A10,C1orf61,CDC42BPA,DNAH17,SLN,PALLD,NHLH1,NPPA,GRIK2,GUCY1A2,TNS1,SEZ6L,NRXN1,MASP1,KIAA0513,NAV2,DSCAM,ELAVL4,ROM1" Drug 2578_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,PKP4,PKNOX2,SLCO1A2,ASPH,RAP1GAP2,ALDH1L1,GPR162,MYRF,NUMA1,PSD3,OMG,OPCML,PADI2,RBFOX2,ZMYND8,FLRT1,PRKCZ,TMCC2,EPB41L1" Drug 6746_UP Calciferol [50-14-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ACTN2,FABP7,AGT,PLA2G6,C1orf61,RASA3,GAS7,CCDC181,GAD2,ADGRB2,GPR17,GRIK2,SPX,POU3F2,CRMP1,PHYHIP,PLPPR4,KCND3,ATN1,DTNA" Drug 5782_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "APC2,FGF1,ANK1,BCAS1,RPH3A,SHANK2,TAGLN3,KIF21B,GPR162,INA,DAAM2,PADI2,MAGI1,ADGRG1,CHI3L2,ETNPPL,FEZ1,RIMS3,PTCH1,KCNJ4" Drug 4435_UP retinoic acid; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "APC2,AGT,MOBP,ANK1,DOCK10,GAS7,PDE8B,KLHL4,GPM6B,GPR17,GRIN1,OMG,TMPRSS5,PLCH2,PTCH1,SMG7,KCNJ4,ABCC9,VWA5A,EN2" Drug 4354_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "FABP7,ADORA1,SLC30A10,SORBS1,SLC1A7,TAGLN3,ASPH,TNIK,ZSWIM8,ACSBG1,PAH,PCDH9,SCRG1,PIK3CD,CABP1,VCAN,MAPK8,KCND3,EN2,BAALC" Drug 2803_DN Yohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "KIAA1109,FHL1,MOBP,CDC42BPA,GAS7,SLN,WDTC1,ZCCHC24,CADM3,B4GALNT1,EMC1,TGFBR3,PC,ADGRG1,SULT4A1,MICAL1,RIMS3,JAKMIP2,RABGAP1L,SIDT2" Drug 2697_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,SEMA6A,FOXG1,ANK2,CCDC88A,DLL3,ASPH,ATP2B2,PHLDB1,TGFBR3,NEURL1,TNS1,CDH10,CHGA,CABP1,MAPK10,KCND3,KCNQ2,RALGDS,RGR" Drug 6001_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "WLS,MDM4,SYBU,DKK3,TNIK,NCAM1,ALDH1L1,PHLDB1,ACSBG1,GPM6B,CACNB2,HAP1,TGFBR3,GUCY1A2,GUCY1A1,NEURL1,CNTN1,JAKMIP2,SSPN,EPB41L1" Drug 3803_UP Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "FGR,APC,SLN,GFRA1,GPM6B,HAP1,CRB1,P2RX7,PTGDR2,TPM3,PDE2A,PDYN,CHI3L2,CABP1,NECAB2,SMG7,AK5,KCNJ4,LMO1,RAVER2" Drug 6658_UP Luteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "RYR1,FGF1,PKP4,APBB1,NTNG1,SHANK2,ATP2B2,SCN3B,ADGRB2,PHLDB1,HAP1,TF,PDE3B,CHRNB2,NECAB2,PTAFR,PRDM2,ATN1,DSCAM,DTNA" Drug 2496_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ADORA1,FOXRED2,HPCAL4,FOXG1,C1orf61,ANK2,PKP4,BCO1,PDE8B,ALDH4A1,CCDC181,SPART,KAZN,WSCD1,ATF7,KIAA0513,KCNMA1,DLG3,RASGRF1,RASGRP2" Drug 3265_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "NDRG2,GAS7,ASCL1,PDE8B,KIF21B,CADM3,LMO3,ALDH1L1,GLS,POPDC3,NPPA,HAP1,TNS1,GPR37L1,PACSIN1,RIMS3,MAGI2,TMCC2,SIDT2,VWA5A" Drug 5790_UP Tropine [120-29-6]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ASIC1,MAPT,APC2,RPH3A,TAGLN3,ATP1A3,GLS,KAZN,BTRC,ZEB1,OMG,PADI2,SEZ6L,PDE2A,IFFO1,PROX1,RIMS3,DSCAM,DTNA,SEC61A2" Drug 4193_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "KIAA1109,ST8SIA1,TNIK,KIF21B,INKA2,ACSBG1,HAP1,DAAM2,CDC42,TNS1,PTGDR2,MAGI1,PDE2A,VAV2,CNTN1,IFFO1,CTNND2,PLPPR1,ST8SIA3,SIDT2" Drug 606_UP (+/-)-thalidomide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ADORA3,FOXRED2,APBB1,GAS7,WDTC1,NAP1L2,SPART,NCAM1,CACNA1A,TMEM151B,PADI2,TNS1,PDE1C,CA14,NRXN1,PIK3CD,ARHGEF4,ECE2,KCNQ2,ATN1" Drug 2745_UP Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,TESK2,APC,WDTC1,RND1,KAZN,GNAS,GNG3,BTRC,CAMK2G,TNS1,PIK3CD,SF1,SNCAIP,MAPK8,MAPK10,BRINP3,PTHLH,EFNA3,LRRC23" Drug 4423_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ASIC1,MAPT,CEND1,ADORA1,KIAA1109,ASIC4,APC,BCO1,DNAH17,GPM6B,GRIN1,P2RX7,GPR37L1,OSBPL3,PTAFR,PID1,SSPN,VWA5A,ELAVL3,RASGRP2" Drug 3701_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "MAPT,ARID1A,ADORA1,AGT,FGF1,TAGLN3,GAD2,ADGRB2,ASTN2,GNG3,GPR19,OPCML,CADM1,TENM4,ITIH2,RABGAP1L,ATN1,RGS10,ELAVL3,LRRC23" Drug 4378_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "EMID1,FGF1,GAS7,SORBS1,RPH3A,SLC2A5,SORCS3,SNAP25,CCDC181,ATP1A2,GAD2,VAMP1,GPM6B,PTGDR2,PDE1C,SULT4A1,NOS1AP,PTPRO,RAD52,DTNA" Drug 5766_UP Skimmianine [83-95-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "MOBP,PKP4,MSR1,SLC8A2,TAGLN3,TNIK,BTRC,PRUNE2,GRM3,OPCML,CDH8,PDE2A,PRMT8,SPATA6,IFFO1,ARHGEF4,RIMS3,ATN1,PAK5,NUP214" Drug 2514_UP Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "AGT,FHL1,FOXG1,ANK3,TAGLN3,B3GALT2,NCAM1,FGF17,ACSBG1,GNAS,WWC1,WSCD1,GPR19,GRIK4,PADI2,HRH3,TMPRSS5,POU3F4,ATRNL1,PTAFR" Drug 5433_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "PLA2G6,AMPH,SLC1A7,SLC2A5,MSR1,SLCO1A2,ASPH,ZCCHC24,CADM3,GLS,PRUNE2,ZEB1,PSD3,ADGRG1,CHI3L2,CHRNB2,SULT4A1,RAD52,DTNA,SIDT2" Drug 6505_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "SORBS1,SLC1A7,CADM3,NDUFA5,FGF17,GLS,GRM3,HPSE2,PLEKHB1,CABP1,SPATA6,IFFO1,RGS6,PROX1,ITIH2,HP1BP3,KCNC1,KCND3,RASGRF1,EFNA3" Drug 6324_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ARID1A,KIAA1109,FGF1,ITSN1,NLGN1,PDE8B,DNAH17,PHLDB1,ASTN2,ADGRL3,USP2,NECAB2,CTNND2,MAPK8,PROX1,MASP1,ATN1,NUP214,SIDT2,ROM1" Drug 4007_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.39E-04 1.00E+00 5.66E-03 6.21E-02 20 199 "ACTN2,MDM4,KIAA1109,FGF14,ANK1,MADD,TNIK,PHLDB1,VAMP1,BTRC,ADGRL3,HAP1,CDC42,TNS1,PLEKHB1,SPATA6,POU3F4,FEZ1,EDRF1,SUSD4" Drug CID000107831 AC1L32TU Stitch 1.40E-04 1.00E+00 5.67E-03 6.21E-02 7 30 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,AIFM1" Drug CID000127894 LY293558 Stitch 1.40E-04 1.00E+00 5.67E-03 6.21E-02 7 30 "GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000001226 "cis-2,3-piperidine dicarboxylic acid" Stitch 1.40E-04 1.00E+00 5.67E-03 6.21E-02 7 30 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3" Drug 4632_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.43E-04 1.00E+00 5.77E-03 6.33E-02 18 169 "ABAT,RTN1,TESK2,SORBS1,TAGLN3,FYN,TNIK,RGL1,PHLDB1,RND1,GLS,PCDH9,DNAJC12,PMP2,PTCH1,DNAJC6,PLPPR4,EFNA3" Drug CID000089234 gamma-aminobutyrylhistidine Stitch 1.46E-04 1.00E+00 5.88E-03 6.45E-02 5 14 "ABAT,GAD2,CNDP1,CP,ELAVL3" Drug CID000004054 memantine Stitch 1.48E-04 1.00E+00 5.90E-03 6.47E-02 12 86 "ACHE,SLC6A9,CNDP1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRIN1,GRM3,CHRNB2,PTPA" Drug 4985_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "MAPT,FHL1,SLC1A7,ZCCHC24,NAP1L2,NDUFA5,SEMA4A,ROBO3,GPR19,CAMK2G,PCDH9,ZFYVE9,PPP2R5C,FEZ1,ARHGEF4,RABGAP1L,ATG16L1,SUSD4,VWA5A,ROM1" Drug 3760_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "NDRG2,ADCY2,RYR1,TRIM46,ANK2,SHANK2,SLC14A1,BRINP2,GPR17,NUMA1,TNS1,CDH8,CHI3L2,ZFYVE9,SPATA6,PTPRO,ARNT2,EFNA3,TMEM100,EPB41" Drug 3056_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "ABAT,MAPT,MOBP,ANK3,SLN,DKK3,B3GALT2,NCAM1,ASTN2,GPM6B,REPS2,PCDH9,CHI3L2,CTNND2,MAPK8,NOS1AP,DNAJC6,NTM,ST8SIA3,EPB41" Drug 369_DN rosiglitazone maleate; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "PPFIA1,DOCK10,ATP1A2,PHLDB1,GLS,KAZN,PADI2,RBFOX2,SEZ6L,TMPRSS5,JAM2,PHKG1,TJP2,CNTN1,NSD2,ECE2,MASP1,KCNA1,PARD6A,RAP1GAP" Drug 3385_DN Nizatidine [76963-41-2]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "MAPT,EMID1,MOBP,RASA3,APBA2,PDE8B,RND1,FAM168A,NRGN,PDE3B,IGSF1,RIMS3,JAKMIP2,PARD6A,PTPRO,RAB3IL1,RAD52,RALGDS,RGS10,SSPN" Drug 2323_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "ADORA1,FHL1,SLC30A10,SELL,APC,GAS7,CCDC88A,SHANK2,ALDH4A1,ADAM15,BTRC,NUMA1,NEURL1,TNS1,SEZ6L,GPR37L1,SNCAIP,MAPK8,MAPK10,ITIH2" Drug 3044_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "SEMA6A,AQP4,SLN,ATP2B2,PALLD,B3GALT2,SOX10,NCAM1,ALDH1L1,ASTN2,PRUNE2,HAP1,ATP13A2,HRH3,SEZ6L,VAV2,CTNND2,DNAJC6,PMEPA1,DSCAM" Drug 5762_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "DPF1,CDC42BPA,PKNOX2,ALDH4A1,ASTN2,GPM6A,HAP1,GRIK2,NEURL1,TNS1,CA14,CHI3L2,PLEKHB1,KIAA1549L,CRMP1,TOX,PTAFR,STMN4,DTNA,LRRC23" Drug 4469_UP Stachydrine hydrochloride; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "PRR5L,FGF1,C1orf61,GAS7,SLC2A5,MSR1,PKNOX2,SLCO1A2,GLS,SEMA4A,PRUNE2,BRSK2,TNS1,PRMT8,SPATA6,IFFO1,ARNT2,PAK5,RGR,LRRC23" Drug 6141_UP Meropenem [96036-03-2]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "SERPINA3,ACTN2,FOXG1,AMPH,CDC42BPA,PKNOX2,ATP1A3,ATP2B2,TNIK,PHLDB1,NEUROD1,BTRC,NPPA,TJP1,PLCH2,PSD,PLPPR1,STMN4,RERGL,ELAVL4" Drug 2147_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "KIAA1109,CDC42BPA,APC,RND1,GNG3,ADGRL3,GPR19,NUMA1,SEZ6L,ZMYND8,FLRT1,SULT4A1,IGSF1,KIF2A,ATN1,EEF1A2,SEC61A2,SIDT2,EFNA3,ELAVL3" Drug 2272_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "KLRC4,RYR1,APC,SLC1A2,SLC2A5,PKNOX2,RND1,GLS,PRUNE2,WSCD1,GPM6A,PTGDR2,TPM3,PIK3CD,VAV2,POU3F4,MAPK8,KCNC1,RAD52,RGS10" Drug 2814_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "NDRG2,PLA2G6,CDC42BPA,APC,BCAN,SLC1A2,DNAH17,DLL3,BRINP2,RND1,AJAP1,POPDC3,SEMA4A,GRIK3,ASIC3,CHRNB2,NOS1AP,PTCH1,PTPRO,RAB3IL1" Drug 3840_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "NDRG2,ADORA1,AGT,PLA2G6,AQP4,PKNOX2,SLN,ZCCHC24,MYH7,SPART,POPDC3,OMG,PCDH8,PIK3CD,PTCH1,PTPRD,SV2A,TMCC2,KCNK2,PAK5" Drug 6023_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "EMID1,ACTN2,HPCAL4,AMPH,SLC1A2,PKNOX2,TAGLN3,FYN,WDTC1,TNIK,CADM3,OPCML,CCKBR,PDYN,VCAN,CNIH3,KCNMA1,ATN1,VWA5A,ELAVL3" Drug 1474_UP Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.49E-04 1.00E+00 5.90E-03 6.47E-02 20 200 "MDM4,FOXG1,ZNF365,SLC2A5,DNAH17,ASPH,BRINP2,ALDH4A1,EMC1,ALDH1L1,NEURL1,SULT4A1,MICAL1,POU3F4,MAPK8,TMEM255A,RAD52,NUP214,SSPN,LRRC23" Drug CID000071273 S-ropivacaine Stitch 1.50E-04 1.00E+00 5.92E-03 6.50E-02 8 40 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,KCND3" Drug ctd:D014501 Uranium CTD 1.52E-04 1.00E+00 5.99E-03 6.56E-02 26 297 "NDRG2,ADAR,SLC44A5,APBB1,APC,NSG2,ASCL1,KIF1B,ABCC8,KAZN,TF,TNFRSF1B,PDE1A,HMGB1,C11orf49,MFSD4A,CP,CRLS1,SDC3,PUM1,DPYSL5,TOMM20,CSDE1,PLEKHB2,DTNA,BAALC" Drug 3103_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.53E-04 1.00E+00 5.99E-03 6.56E-02 19 185 "C1orf61,CDC42BPA,ANK3,SORBS1,PDE8B,DNAH17,CCDC181,ZSWIM8,NPPA,INA,HRH3,PDE4B,SLC22A6,ZFYVE9,KIAA0513,CNIH3,PID1,ST8SIA3,ROM1" Drug CID005311355 SCH 51866 Stitch 1.53E-04 1.00E+00 5.99E-03 6.56E-02 4 8 "NPPA,PDE1C,PDE2A,PDE4B" Drug CID000128784 "1,3-dipropyl-8-phenylxanthine" Stitch 1.53E-04 1.00E+00 5.99E-03 6.56E-02 4 8 "ADORA1,ADORA3,TUB,DPP6" Drug CID000194385 homoibotenic acid Stitch 1.53E-04 1.00E+00 5.99E-03 6.56E-02 4 8 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000127037 "2,3-PDCA" Stitch 1.53E-04 1.00E+00 5.99E-03 6.56E-02 4 8 "SLC1A2,GRIA1,GRIA2,GRIA4" Drug CID003248290 Iem 1460 Stitch 1.53E-04 1.00E+00 5.99E-03 6.56E-02 4 8 "GRIA1,GRIA2,GRIA4,GRM3" Drug 1014_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.54E-04 1.00E+00 6.01E-03 6.59E-02 18 170 "ADD3,PPM1E,SORBS1,SYBU,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PADI2,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2" Drug ctd:C055494 caffeic acid phenethyl ester CTD 1.54E-04 1.00E+00 6.01E-03 6.59E-02 27 314 "SERPINA3,ADCY2,FABP7,HPCAL4,RPH3A,SLC6A9,SOX10,NCAM1,GFAP,GJB1,NFIA,GLS,CACNA1A,GPR19,GRIK2,OLR1,LGI1,PCSK2,ZNF384,CRMP1,RGS6,KCNT2,SLC45A1,KCNQ2,OLIG1,RET,RPE65" Drug CID000005734 zonisamide Stitch 1.54E-04 1.00E+00 6.03E-03 6.61E-02 10 62 "ABAT,ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,CA14,ASIC3,PTCH1" Drug ctd:D010269 Paraquat CTD 1.55E-04 1.00E+00 6.06E-03 6.64E-02 95 1647 "MAG,EPS8,SERPINA3,ASIC1,MAPT,ACHE,MDM4,ADAR,ADORA1,AGT,FGF1,BBOX1,FOXM1,AMPH,ANK1,SH3GL2,APBB1,SORBS1,MSRA,SLC6A9,MT3,CCDC88A,ASCL1,SCG3,TMEM108,ATM,ATP1A2,FYN,ATP2B2,PALLD,GABBR1,SOX1,GAD2,TTC9B,KIF1B,GART,FXYD6,BCL2L2,GFAP,GFRA1,GJB1,NEUROD1,MLC1,GLS,OS9,SEMA4A,GNAS,FAM69C,ACSL6,CACNA1E,NRDC,CAMK2A,GRIA2,GRIK3,GRIN1,ATP13A2,TF,CCKBR,P2RX7,GUCY1A1,TJP1,AIFM1,DAAM2,PAX6,TNR,PDYN,ADGRG1,HMGB1,PFKFB3,CHRNB2,HNRNPK,SLC22A6,NRXN2,FADS2,CABP1,FAT3,FEZ1,PRKCZ,CTNND1,CTNND2,MAPK8,MAPK10,NOS1AP,SIRPA,BLOC1S6,KCNA1,KCNA2,KCNA4,ARNT2,KCNMA1,DNM2,GOPC,RTN4,ABCC9,EEF1A2" Drug CID000074537 "1, 3-diallylurea" Stitch 1.56E-04 1.00E+00 6.07E-03 6.66E-02 11 74 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,DNER,CACNA1E,ASIC3,CHRM1,TOX" Drug CID000002653 AC1L1E5T Stitch 1.56E-04 1.00E+00 6.07E-03 6.66E-02 11 74 "ADCY2,SLC1A2,SLC8A2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,PTAFR" Drug 4460_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.64E-04 1.00E+00 6.36E-03 6.97E-02 19 186 "ACTN2,ADD3,TMEM156,TESK2,KIAA1109,FOXG1,TRIM46,ATM,RND1,TCF7L2,NUMA1,PSD3,PDE4B,FEZ1,DZIP3,PKN2,EDRF1,PTCH1,SMG7" Drug 6051_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.64E-04 1.00E+00 6.36E-03 6.97E-02 19 186 "ASIC1,MAPT,TESK2,SHANK2,CAPRIN2,ALDH4A1,GLS,VAMP1,ASTN2,GNG4,PSD3,ZMYND8,PLEKHB1,RIMS3,LRP8,PARD6A,RAB5B,RET,EFNA3" Drug 4237_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.66E-04 1.00E+00 6.41E-03 7.03E-02 18 171 "ABAT,TESK2,TAGLN3,BRINP2,FYN,TNIK,RGL1,RND1,GLS,HAP1,PCDH9,CHRNB2,SERPINE2,PIK3CD,DNAJC12,PLPPR4,EFNA3,VWA5A" Drug 3791_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.66E-04 1.00E+00 6.41E-03 7.03E-02 18 171 "ABAT,MAPT,TUBB4A,SORBS1,TAGLN3,SNCB,FYN,TNIK,ADGRB2,RGL1,RND1,CDK5R2,PCDH9,PDE2A,DNAJC12,SYTL2,PLPPR4,EFNA3" Drug CID000162797 HWA 153 Stitch 1.68E-04 1.00E+00 6.47E-03 7.10E-02 6 22 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000148184 CX516 Stitch 1.68E-04 1.00E+00 6.47E-03 7.10E-02 6 22 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug ctd:C523799 MRK 003 CTD 1.73E-04 1.00E+00 6.68E-03 7.32E-02 52 775 "EPS8,GRAMD1B,ADORA3,SLC44A5,FCGR1A,BBOX1,CDC42BPA,GPAM,SORBS1,STK32C,SLC2A5,MSR1,MSRA,ASCL1,DLL3,SORCS3,SNAP25,MEGF11,B3GALT2,ADAM15,MIR100HG,PHLDB1,PRUNE2,GPM6B,ACSL6,CACNB2,CRB1,TMEM25,TGFBR3,PC,CDH10,ARHGAP22,CPT1C,PRRX1,RGS6,RBPJ,ARHGEF4,HES5,SYTL2,CEP170,RABGAP1L,KCNK2,KCNMA1,KCNQ2,RAB3IL1,DSCAM,BEND5,RGS7,INSYN2,SSPN,ELAVL4,EPB41" Drug CID000001216 AP-5 Stitch 1.75E-04 1.00E+00 6.75E-03 7.40E-02 15 128 "ADORA1,B3GAT1,CPLX2,CACNB2,NRGN,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRIN1,GRM3,CHRM1,PRKCG" Drug 4463_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.76E-04 1.00E+00 6.76E-03 7.42E-02 19 187 "TESK2,FOXG1,ANK1,SLC8A2,ASPH,ATM,RND1,NUMA1,OPCML,PDE4B,NMT2,SF1,PRKAB2,MAPK8,PUM1,EDRF1,MASP1,DSCAM,RET" Drug CID000071329 dofetilide Stitch 1.77E-04 1.00E+00 6.81E-03 7.46E-02 10 63 "KCNIP2,SCN4B,ANK2,SCN3B,ASIC3,KCNA4,KCND3,KCNH1,KCNK2,RGR" Drug 2330_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.78E-04 1.00E+00 6.84E-03 7.50E-02 18 172 "ADD3,PPM1E,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,RASGRP2" Drug CID000005411 tetracaine Stitch 1.85E-04 1.00E+00 7.08E-03 7.77E-02 12 88 "ACHE,ADCY2,RYR1,SCN4B,SCN3B,KCNK10,ASIC3,CHRNB2,PRKCG,PKN2,PRKCZ,KCNK1" Drug CID000001775 phenytoin Stitch 1.86E-04 1.00E+00 7.11E-03 7.80E-02 21 219 "ABAT,ASIC1,ACHE,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,LGI3,SCN3B,CACNA1A,CACNA1E,CACNB2,ASIC3,ATCAY,DPYSL5,PTCH1,PTHLH,KCNA1,KCNA2,CACNG7" Drug CID000008146 DE gel Stitch 1.86E-04 1.00E+00 7.12E-03 7.80E-02 16 143 "ADORA1,ACTL6B,NLGN1,B3GAT1,CACNB2,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,POU3F4,HES5,PRDM2" Drug CID000003541 AC1MBZ1C Stitch 1.88E-04 1.00E+00 7.18E-03 7.88E-02 31 387 "ADCYAP1R1,ADORA1,ADORA3,PLA2G6,FOXM1,SNAP25,ATP2B2,GNAS,CACNA1A,CACNA1E,NPPA,CACNB2,GRIA1,CCKBR,TJP1,HRH3,PDE1C,PDE3B,PDE4B,CHRM1,CAMKV,PIK3CD,PRKACB,CALY,PRKCG,MAPK8,PTHLH,KCNA4,KCND3,RAP1GAP,CAMK1G" Drug CID000002834 AC1L1EKQ Stitch 1.88E-04 1.00E+00 7.18E-03 7.88E-02 9 52 "GNAS,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,PDE3B" Drug 5419_UP Methotrexate [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.88E-04 1.00E+00 7.18E-03 7.88E-02 19 188 "ARID1A,PLA2G6,FHL1,HPCAL4,RPH3A,FYN,WDTC1,RND1,NRGN,USP2,CDC42,CHRNB2,CNTN1,MAPK10,RIMS3,ATN1,RASGRF1,DTNA,TTLL7" Drug 5308_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.92E-04 1.00E+00 7.29E-03 7.99E-02 18 173 "ADD3,SYBU,PKNOX2,CAPRIN2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,VAMP1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,EFNA3" Drug 1659_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.92E-04 1.00E+00 7.29E-03 7.99E-02 18 173 "F3,ADD3,TUBB4A,PPM1E,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PCDH9,PIK3CD,DNAJC12,MAPK8,KIAA0513,PTCH1,DNAJC6,JAKMIP2" Drug ctd:D002118 Calcium CTD 1.92E-04 1.00E+00 7.31E-03 8.01E-02 37 495 "ASIC1,RYR1,AGT,FGF1,PLA2G6,SLC8A2,SLC8A3,GABBR1,GFAP,GNAS,CACNA1A,CACNA1E,DDR1,GRIA1,GRIA2,USP2,P2RX7,TJP1,PAX6,CDC42,PTGDR2,HRH3,CHRM1,CHRNB2,HPCA,NRXN1,PIK3CD,UBTF,BEST1,CP,PRKCG,PTAFR,ITIH2,KCNJ11,KCNMA1,KCNN3,RALGDS" Drug ctd:D019287 Zinc Sulfate CTD 2.01E-04 1.00E+00 7.63E-03 8.37E-02 50 741 "APC2,EMID1,TUBB4A,FGF1,MOG,TRIM46,APBB1,SESN3,LRRC55,CADPS,SCG3,TAGLN3,SNAP25,MEGF11,MYH7,SLCO1C1,SYT4,NKX2-2,KAZN,GNAS,NODAL,CNTN2,P2RX7,AIFM1,TLL2,TPM4,PCSK2,MAGI1,PDE4B,GPR37L1,CHGA,PFKFB3,CADM1,NECAB2,CP,FEZ1,CHD5,MAPK8,PROX1,SPIRE1,PLPPR1,MAGI2,PTPRD,DLG2,WIPF2,KLRC3,RASGRF1,ABCC9,EEF1A2,SIDT2" Drug 6966_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.02E-04 1.00E+00 7.63E-03 8.37E-02 19 189 "MAPT,F3,FHL1,HPCAL4,CDC42BPA,BCAS1,PKNOX2,CCDC88A,GPR153,NAP1L2,GRIA1,PDE1C,ZMYND8,PUM1,EDRF1,KLK6,KCNC1,RAB3IL1,RASGRP2" Drug 2729_UP Securinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.02E-04 1.00E+00 7.63E-03 8.37E-02 19 189 "MAPT,PLA2G6,HPCAL4,CDC42BPA,DNAH17,AJAP1,ADGRL3,GPM6B,ADAMTS8,PDE3B,JAM2,ZFYVE9,BEST1,NECAB2,PKN2,CTNND1,NUP214,EN2,RASGRP2" Drug 2672_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.02E-04 1.00E+00 7.63E-03 8.37E-02 19 189 "EPS8,EMID1,ARHGAP5,DNAH17,TNIK,NCAM1,RGL1,CAMSAP2,PSD3,PCDH9,CDH10,SEZ6L,DZIP3,RIMS3,DNAJC6,MAGI2,PARD6A,LPAR6,EN2" Drug 6085_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.06E-04 1.00E+00 7.78E-03 8.53E-02 18 174 "ADD3,TUBB4A,PPM1E,SORBS1,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug CID000005092 rolipram Stitch 2.07E-04 1.00E+00 7.81E-03 8.57E-02 23 253 "MBP,FABP7,ADORA1,ADORA3,PDE8B,NPPA,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,GUCY1A2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,PMP2,PTPA,PRKACB" Drug CID003035667 thiokynurenic acid Stitch 2.11E-04 1.00E+00 7.96E-03 8.73E-02 5 15 "GAD2,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000001218 SKF 81297 Stitch 2.15E-04 1.00E+00 8.07E-03 8.85E-02 8 42 "ABAT,GNAS,GRIA1,GRIA2,GRIA4,GRM3,HRH3,PDYN" Drug CID005311037 KW-6002 Stitch 2.16E-04 1.00E+00 8.11E-03 8.89E-02 7 32 "ADORA1,ADORA3,GRIA1,GRIA2,GRIA4,GRM3,PDYN" Drug CID000001222 alpha-methyl-4-carboxyphenylglycine Stitch 2.16E-04 1.00E+00 8.11E-03 8.89E-02 7 32 "B3GAT1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000096918 atherosperminine Stitch 2.19E-04 1.00E+00 8.20E-03 8.99E-02 6 23 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID005486547 YM90K Stitch 2.19E-04 1.00E+00 8.20E-03 8.99E-02 6 23 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000127607 griseolic acid Stitch 2.19E-04 1.00E+00 8.20E-03 8.99E-02 6 23 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug 4153_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.21E-04 1.00E+00 8.27E-03 9.07E-02 18 175 "TUBB4A,HPCAL4,SORBS1,PKNOX2,CCDC88A,FYN,ZCCHC24,NMNAT2,RGL1,RND1,ACSBG1,PAH,TNS1,PIK3CD,DNAJC12,KIAA0513,TTLL7,RASGRP2" Drug CID000002012 AC1L1CQC Stitch 2.31E-04 1.00E+00 8.60E-03 9.43E-02 10 65 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1,PHYHIP,PMEPA1" Drug 4471_DN Astemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.31E-04 1.00E+00 8.60E-03 9.43E-02 19 191 "ASIC1,PAQR6,APBB1,WDTC1,KAZN,TCF7L2,CAMK2G,TGFBR3,PDE1C,KIAA1549L,NMT2,SDC3,MAPK8,PTCH1,KIF2A,ATG16L1,DTNA,TTLL7,EPB41L1" Drug 3291_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.31E-04 1.00E+00 8.60E-03 9.43E-02 19 191 "SERPINA3,SYNDIG1,ACTN2,FHL1,ALDH4A1,WDTC1,SOX10,PHLDB1,ABCC8,GLS,GNG4,GRM3,CRMP1,ATRNL1,CHD5,VCAN,MAPK8,PTAFR,VWA5A" Drug 4451_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.31E-04 1.00E+00 8.60E-03 9.43E-02 19 191 "ACTN2,GRAMD1B,TMEM156,TESK2,ASIC4,ASPH,RND1,GNG4,GPM6B,TCF7L2,NUMA1,PDE3B,PDE4B,ZMYND8,MAPK8,EDRF1,KCNJ4,RABGAP1L,RASGRF1" Drug ctd:C009250 sevoflurane CTD 2.38E-04 1.00E+00 8.85E-03 9.71E-02 21 223 "SLC25A25,GPAM,SLC6A9,DLL3,GABBR1,GAD2,CNTN2,VWC2,NPPA,ADAMTS8,CCKBR,USP2,MFSD2A,P2RX7,PDE3B,PDE4B,PFKFB3,FADS2,KCNT2,PRKACB,SLC17A6" Drug CID000010083 pipradrol Stitch 2.43E-04 1.00E+00 8.99E-03 9.85E-02 3 4 "FOXM1,SOX10,POU3F2" Drug CID000574311 3-pyridazinol 1-oxide Stitch 2.43E-04 1.00E+00 8.99E-03 9.85E-02 3 4 "GRIA1,GRIA2,GRIA4" Drug DB00201 Caffeine Drug Bank 2.43E-04 1.00E+00 8.99E-03 9.85E-02 3 4 "RYR1,ADORA1,PDE4B" Drug CID000193141 AH6405 Stitch 2.43E-04 1.00E+00 8.99E-03 9.85E-02 3 4 "ACHE,CCDC88A,CHRM1" Drug CID000016697 NTMP Stitch 2.43E-04 1.00E+00 8.99E-03 9.85E-02 3 4 "GNAS,TF,NTM" Drug 5967_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-04 1.00E+00 9.10E-03 9.98E-02 19 192 "ADORA1,LRRTM4,SEMA6A,APC,FYN,ALDH1L1,RND1,GLS,HAP1,USP2,TNS1,PDE1C,HPSE2,PMP2,PACSIN1,MAPK8,KCNJ9,KCNMA1,RASGRF1" Drug 4303_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-04 1.00E+00 9.10E-03 9.98E-02 19 192 "ACHE,ACTN2,TUBB4A,FHL1,ASCL1,WDTC1,GAD2,KLHL4,PRUNE2,NRGN,NUCB1,ADGRG1,IFFO1,EDRF1,RIMS3,PRDM2,NAV2,PARP11,ATN1" Drug 4442_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-04 1.00E+00 9.10E-03 9.98E-02 19 192 "GRAMD1B,HPCAL4,FOXG1,SORBS1,NLGN1,AQP4,MYT1L,NEUROD1,HAP1,CAMK2G,GRIN1,TPM3,PDE4B,CABP1,OSBPL3,EDRF1,PTCH1,RABGAP1L,RET" Drug CID006324636 LY341495 Stitch 2.54E-04 1.00E+00 9.34E-03 1.02E-01 8 43 "RYR1,FOLH1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 6784_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.55E-04 1.00E+00 9.34E-03 1.02E-01 18 177 "ADD3,SEMA6A,FHL1,SORBS1,FYN,TNIK,ZCCHC24,RGL1,ACSBG1,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTCH1,DNAJC6,JAKMIP2,EFNA3,RASGRP2" Drug 7387_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.55E-04 1.00E+00 9.34E-03 1.02E-01 18 177 "TESK2,SORBS1,TAGLN3,FYN,TNIK,ZCCHC24,RGL1,RND1,GLS,USP2,PCDH9,DNAJC12,RIMS3,SYTL2,DNAJC6,PLPPR4,EFNA3,VWA5A" Drug 5945_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.55E-04 1.00E+00 9.34E-03 1.02E-01 18 177 "TUBB4A,SORBS1,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,ZEB1,PCDH9,PIK3CD,DNAJC12,TTLL7,EFNA3,VWA5A" Drug CID000002083 salbutamol Stitch 2.56E-04 1.00E+00 9.36E-03 1.03E-01 16 147 "ASIC1,ADCY2,FCGR1A,SCN3A,SCN4B,SCNN1D,ASIC4,FOXM1,ZNF365,SCN3B,NEUROD1,GNAS,PDE4B,ASIC3,CHRM1,TMEFF2" Drug CID005327099 AC1NS1NG Stitch 2.56E-04 1.00E+00 9.36E-03 1.03E-01 16 147 "MAG,ADGRV1,LRRC7,MOBP,MOG,ST8SIA1,FYN,ATP2B2,B4GALNT1,NEU4,OMG,CD81,CHRNB2,PRKCG,PKN2,PRKCZ" Drug CID000003114 disopyramide Stitch 2.63E-04 1.00E+00 9.59E-03 1.05E-01 10 66 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3,CHRM1,CHRNB2,KCNA4" Drug 5998_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "EMID1,WLS,SEMA6A,FHL1,AMPH,RASA3,DOCK10,GAS7,SLC6A9,FYN,NCAM1,CAMK2A,HRH3,KIAA1549L,MICAL1,CRMP1,PROX1,CRTAC1,RASGRP2" Drug 5315_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "SERPINA3,ASIC4,GAS7,ZNF365,RPH3A,ATM,FYN,WDTC1,ZCCHC24,KAZN,SERPINE2,CNTN1,PPP2R5C,NAV2,NKAIN1,DSCAM,SIDT2,ROM1,EPB41L1" Drug 4712_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "ADORA1,FOXG1,CDC42BPA,BCO1,ALDH1L1,PHLDB1,TNS1,HPSE2,KIAA1549L,PMP2,CRMP1,NOS1AP,PTAFR,NAV2,RAD52,DSCAM,FAM13C,SSPN,EN2" Drug 1696_UP Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "NDRG2,SYBU,ASPH,PALLD,GAD2,INKA2,CACNB2,GPR37L1,CADM1,CNTN1,SDC3,ARHGEF4,MAPK8,EDRF1,RIMS3,NAV2,RAD52,DTNA,RGS10" Drug 6050_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "CEND1,TUBB4A,PKNOX2,ASTN1,SNAP25,ATP1A2,TNIK,GAD2,GPR162,RGL1,ATF7,CRB1,INA,SDC3,CNIH3,SLC17A6,ATN1,ST8SIA3,TTLL7" Drug 5922_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 9.59E-03 1.05E-01 19 193 "HPCAL4,SLN,GAD2,ADGRB2,GFRA1,GNAS,BTRC,GRIK2,PADI2,MAGI1,CADM1,SPATA6,FAM131B,PTAFR,PRDM2,SMG7,RABGAP1L,ATN1,ARHGEF10L" Drug CID002724608 "6,7-dinitroquinoxaline" Stitch 2.65E-04 1.00E+00 9.59E-03 1.05E-01 7 33 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,MAPK10" Drug ctd:C551178 PF-04254644 CTD 2.66E-04 1.00E+00 9.60E-03 1.05E-01 4 9 "PDE1A,PDE1C,PDE2A,PDE3B" Drug CID000175064 LY97241 Stitch 2.66E-04 1.00E+00 9.60E-03 1.05E-01 4 9 "KCNA1,KCNA2,KCNA4,KCNH1" Drug ctd:D015853 Cysteine Proteinase Inhibitors CTD 2.66E-04 1.00E+00 9.60E-03 1.05E-01 4 9 "ANXA7,PLPPR5,PLPPR1,PLPPR4" Drug CID000004141 methylfurmethide Stitch 2.66E-04 1.00E+00 9.60E-03 1.05E-01 4 9 "ACHE,GNAS,CACNA1A,CHRM1" Drug CID005388938 Py-3 Stitch 2.66E-04 1.00E+00 9.60E-03 1.05E-01 4 9 "F3,SERPINE2,CP,RET" Drug CID000105091 Fura-2AM Stitch 2.82E-04 1.00E+00 1.01E-02 1.11E-01 11 79 "MAG,RYR1,AGT,PLA2G6,SLC8A2,ATP2B2,CNTN2,CACNB2,NRGN,CCKBR,PRKCG" Drug 1020_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "ASIC1,MAPT,EMID1,NDRG2,FHL1,PPM1E,ZNF365,BCO1,GPR153,CAPRIN2,FYN,ZCCHC24,GNG4,DNAJC12,PTCH1,RALGDS,L1CAM,SIDT2,EFNA3" Drug 6510_UP Scopoletin [92-61-5]; Up 200; 20.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "NDRG2,PLA2G6,SEMA6C,APBA2,SYBU,BCO1,SLC14A1,PHLDB1,GNAS,PSD3,OMG,NSD2,PTHLH,HP1BP3,STMN4,DPP6,DTNA,SSPN,EFNA3" Drug 5699_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "RYR1,FHL1,RASA3,SLC2A5,SORCS3,ASTN1,NEUROD1,RND1,VAMP1,GRIA1,OMG,SPX,CDH8,FLRT1,MICAL2,PHYHIP,KCNH1,DSCAM,BAALC" Drug 3641_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "EYA1,RYR1,ASIC4,GAS7,SHANK2,NMNAT2,LMO3,ADGRL3,WSCD1,GPM6A,USP2,KCNK10,PCDH9,VAV2,NECAB2,CRMP1,MICAL2,CNIH3,KCND3" Drug 2687_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "SH3GL2,SCG3,ASPH,ATP2B2,ACSBG1,GNAS,GPM6B,NEURL1,CDH10,GPR37L1,CHGA,CHI3L2,PMP2,CABP1,DZIP3,KCND3,RASGRF1,ST8SIA3,EPB41" Drug 2813_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.82E-04 1.00E+00 1.01E-02 1.11E-01 19 194 "ADORA1,KIAA1109,PLA2G6,SEMA6A,ATM,EMC1,NDUFA5,FAM168A,GLS,SEMA4A,PCDH9,ACOT7,ASIC3,PKN2,NOS1AP,SYNC,PTPRO,DNAH9,VWA5A" Drug CID006437837 CGP 39653 Stitch 2.82E-04 1.00E+00 1.01E-02 1.11E-01 6 24 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000001547 2-chloro-N6-cyclopentyladenosine Stitch 2.82E-04 1.00E+00 1.01E-02 1.11E-01 6 24 "ADARB2,ADORA1,ADORA3,GRM3,PTPN5,HPR" Drug CID000000187 acetylcholine Stitch 2.85E-04 1.00E+00 1.02E-02 1.12E-01 29 361 "ACHE,ACLY,ADCY2,ADORA1,ADORA3,AGT,B3GAT1,SNAP25,ATP1A2,ATP1A3,GAD2,ABCC8,CACNA1E,NPPA,GRIA1,ZFP91,HRH3,PDYN,CHRM1,CHRNB2,HNRNPK,PRKCG,PKN2,PRKCZ,KLK6,KCNA2,SV2A,KCNJ4,KCNMA1" Drug CID006480473 AC1O59H4 Stitch 2.93E-04 1.00E+00 1.04E-02 1.14E-01 9 55 "ADAR,ADARB2,ASCL1,MTR,AHCYL1,ALDH1L1,NEUROD1,HNRNPK,EPB41" Drug 4619_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-04 1.00E+00 1.04E-02 1.14E-01 18 179 "RTN1,GRAMD1B,GAS7,TACC2,BRINP2,BCL2L2,PHLDB1,ADGRL3,PRUNE2,PDE4B,ACOT7,ADGRG1,MICAL2,ARHGEF4,PMEPA1,PTHLH,ARNT2,USH1C" Drug CID005460104 phosphatidate Stitch 2.96E-04 1.00E+00 1.05E-02 1.15E-01 33 433 "ACLY,MBP,RTKN,ADCY2,PLA2G6,ACTL6B,ANK1,ANK2,ANK3,FOLH1,ANXA7,APC,DGKZ,GPAM,DGKD,ARFGAP1,NCDN,NRGN,KCNK10,CDC42,PCDH8,CHRM1,PRKACB,PRKCG,PKN2,PRKCZ,PSD,PLPPR5,KCNH1,KCNK2,RALGDS,ABI1,BSCL2" Drug CID000003639 hydrochlorothiazide Stitch 2.99E-04 1.00E+00 1.05E-02 1.16E-01 14 120 "ASIC1,ACLY,ADCY2,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,NPPA,CA14,ASIC3,SLC22A6,KCNMA1" Drug CID006450346 ganglioside GD2 Stitch 3.00E-04 1.00E+00 1.05E-02 1.16E-01 8 44 "MAG,ST8SIA1,B3GAT1,B4GALNT1,NCAM1,CNTN2,CD81,PAX6" Drug 2875_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ASIC1,PLA2G6,FOXG1,CDC42BPA,PKNOX2,ATP2B2,WDTC1,RGL1,RND1,TNR,CHRNB2,SERPINE2,PACSIN1,PTHLH,RAB3IL1,ATN1,NUP214,SSPN,RAVER2" Drug 3719_DN Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ASIC1,MAPT,APC,ADAM15,ADGRB2,MYRF,CACNA1A,GPM6B,PDE4B,PLEKHB1,PTCH1,PLPPR1,PARD6A,RAB3IL1,ATN1,DTNA,SIDT2,VWA5A,LRRC23" Drug 6696_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ACTN2,MDM4,FOXG1,SFPQ,APBB1,APC,ZSWIM8,ADGRB2,CRB1,ADGRG1,UBTF,NSD2,VCAN,CTNND2,JAKMIP2,RAB3IL1,RAD52,DTNA,EFNA3" Drug 402_UP rapamycin; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "EYA1,NDRG2,ADCYAP1R1,PLA2G6,C1orf61,BCAS1,SHANK2,ATP2B2,NMNAT2,LMO3,HAP1,GUCY1A1,HAPLN2,CHGA,PMEPA1,KCNJ10,LPAR6,ROM1,LRRC23" Drug 5261_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "EMID1,FHL1,ANK1,NLGN1,SLC1A2,RPH3A,TAGLN3,FYN,GAD2,SPART,POPDC3,ATF7,TNS1,GPR37L1,VAV2,POU3F2,NTM,DTNA,CRTAC1" Drug 2152_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ACTN2,TUBB4A,SCN3A,ANK3,SLC14A1,GPR153,ALDH1L1,CAMSAP2,TGFBR3,MAGI1,NCAN,EDRF1,NOS1AP,SYTL2,ITIH2,SUSD4,PAK5,SSPN,ELAVL4" Drug 524_DN nordihydroguaiaretic acid; Down 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ASIC1,NDRG2,FGR,ARHGAP5,ASCL1,NMNAT2,ZNF638,GNG4,NRGN,PDE3B,DNAJC12,PMS2,PACSIN1,PPP3CB,CTNND1,BRINP3,DLG3,SIDT2,EFNA3" Drug 3038_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "MBP,ASIC4,FOXG1,SHANK2,DLL3,GAD2,B4GALNT1,ROBO3,GPR19,GRM3,PTGDR2,HRH3,FLRT1,CNTN1,PMEPA1,MAGI2,KCND3,ATN1,USH1C" Drug 1984_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ASIC1,ACLY,ACTN2,TESK2,KIAA1109,ZCCHC24,GART,ARHGEF7,BTRC,NRGN,CA14,ZFYVE9,DNAJC12,FTO,PTPA,PPP3CB,OSBPL3,SMG7,RAB3IL1" Drug 4696_UP Ofloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "DPF1,KIAA1109,CDC42BPA,CCDC88A,BRINP2,B3GAT1,KAZN,WSCD1,GPM6B,TCF7L2,TGFBR3,PDE4B,VAV2,PMP2,PRDM2,KCNC1,RAB3IL1,RAD52,ATN1" Drug 7361_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "NDRG2,PPM1E,ALDH4A1,ZCCHC24,GNG3,PRUNE2,CCKBR,PAX6,PC,PADI2,FEZ1,GON4L,DNAJC6,RABGAP1L,KCNMA1,RAD52,DSCAM,GNE,LRRC23" Drug 3669_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "PLA2G6,HPCAL4,SLC1A2,SLC1A7,SLCO1A2,BRINP2,LMO3,GPM6B,GRIK2,TPM3,PDE4B,ZMYND8,PIK3CD,NOS1AP,RIMS3,PTHLH,ARNT2,PID1,ATN1" Drug 4781_UP Benperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 1.05E-02 1.16E-01 19 195 "ACHE,EMID1,RYR1,MOBP,DLL3,BRINP2,ATM,FYN,DKK3,WDTC1,GAD2,AJAP1,WSCD1,GUCY1A2,HPCA,OSBPL3,PHYHIP,CNIH3,EFNA3" Drug 4541_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.13E-04 1.00E+00 1.09E-02 1.19E-01 18 180 "ARID1A,WAC,GRAMD1B,BCAR3,APC,TACC2,SYBU,ARHGEF7,TCF7L2,ZEB1,ZMYND8,PFKFB3,ZBED5,PUM1,PRDM2,NAV2,KIF2A,JMJD1C" Drug 4344_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.13E-04 1.00E+00 1.09E-02 1.19E-01 18 180 "DPF1,ABAT,MAPT,F3,SORBS1,BRINP2,FYN,TNIK,NFASC,RGL1,USP2,PCDH9,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,PLPPR4" Drug 3787_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.13E-04 1.00E+00 1.09E-02 1.19E-01 18 180 "ABAT,MAPT,TUBB4A,SORBS1,TAGLN3,BRINP2,SNCB,FYN,TNIK,RGL1,RND1,USP2,PCDH9,PIK3CD,DNAJC12,PLPPR4,SRGAP3,EFNA3" Drug ctd:D013849 Thimerosal CTD 3.15E-04 1.00E+00 1.09E-02 1.19E-01 72 1198 "PRR5L,RIMKLA,CDHR1,ADGRV1,MRVI1,FABP7,LRRC7,SEMA6A,C1QTNF4,SFPQ,ANK2,APC,USP16,RUFY2,ARHGAP5,MT3,MTR,SNAP25,ATM,SON,KIF21B,CADM3,ADGRB2,FXYD6,NPAS3,NASP,NCAM1,CLASP2,NDUFA5,RCOR2,GLS,GNG4,ADGRL3,ANO4,NRDC,PTBP2,SYT6,GRIK2,GRIN1,AIFM1,CD81,PC,CDH8,TPD52,TPM4,PCSK2,HMGB1,CA14,PLEKHB1,TMEFF2,NEGR1,FADS2,COL9A2,PACSIN1,SNCAIP,RBPJ,PRKAB2,ARHGEF4,MAPK8,FGFR1OP2,GON4L,SIRPA,CA10,CADM2,ELMO1,PRDM2,MAGI2,OCIAD1,JMJD1C,EEF1A2,FGFBP3,EPB41L1" Drug 4434_UP alpha-estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ADORA1,ASIC4,FOXG1,PPM1E,APBB1,NLGN1,SLC1A2,SLC2A5,PKNOX2,SLCO1A2,CADM3,ALDH1L1,INKA2,HAP1,CRB1,PDE3B,SDC3,DSCAM,DTNA" Drug 2950_UP Roxarsone [121-19-7]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ACTN2,ADCY2,RYR1,FHL1,TRIM46,AMPH,RASA3,PKP4,GPR153,ALDH4A1,PALLD,WWC1,TJP1,MAGI1,CNTN1,DZIP3,CTNND2,PTPRZ1,RASGRP2" Drug 4182_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MAPT,ARID1A,FHL1,C1orf61,APBA2,GAS7,SLC1A7,DNAH17,SNAP25,ZCCHC24,NPAS3,INKA2,RND1,WSCD1,SNCAIP,SDC3,SRGAP3,TMCC2,ATN1" Drug 6468_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "EMID1,SLC1A2,SLCO1A2,TAGLN3,GFAP,WSCD1,ZEB1,NUMA1,OPCML,CCKBR,KCNK10,CDH8,ZFYVE9,CAMKV,CRMP1,TENM4,DZIP3,ITIH2,KCNC1" Drug 4714_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ASIC1,MAPT,ADCY2,KLRC4,SYBU,ATM,PHLDB1,POPDC3,PDE4B,ZMYND8,CHD1L,PTHLH,PRDM2,KCNMA1,RAD52,ATN1,TTLL7,ROM1,RASGRP2" Drug 3530_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "PLA2G6,FHL1,CDC42BPA,APC,SYBU,SLC1A7,SCMH1,CADM3,CACNB2,PSD3,PDE3B,ZMYND8,PACSIN1,SDC3,EDRF1,SYNC,TMCC2,RAB3IL1,PARP11" Drug 3732_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ACTN2,HPCAL4,APBB1,APC,GAS7,NLGN1,DNAH17,GAD2,INKA2,GNG3,GPR19,ZMYND8,CADM1,PKN2,EDRF1,PSMD13,RAD52,DSCAM,NUP214" Drug 2306_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "RYR1,FGF14,FHL1,APBA2,SORBS1,SHANK2,SLC14A1,DNAH17,SPART,INKA2,KAZN,ADAMTS8,JAM2,PTCH1,STMN4,KCND3,NTM,ELAVL3,RCAN2" Drug 2569_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "EMID1,NDRG2,C1orf61,PKNOX2,ATP1A3,TNIK,NAP1L2,PRUNE2,CDH8,CTNND2,MAPK8,EDRF1,KLK6,PTAFR,ITIH2,RABGAP1L,ATN1,SSPN,OLIG2" Drug 3387_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "CEND1,TUBB4A,FOXG1,C1orf61,ANK1,GAS7,MSR1,TAGLN3,POPDC3,GPM6A,CACNB2,CDH8,PDE4B,IFFO1,SDC3,MAPK8,NTM,NUP214,RGS10" Drug 2249_DN Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ACTN2,NDRG2,KIAA1109,SEMA6A,CDC42BPA,ALDH4A1,EMC1,WSCD1,PC,SERPINE2,NSD2,MICAL2,SDC3,PUM1,RIMS3,SYNC,JAKMIP2,WIPF2,EPB41L2" Drug 4105_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "WLS,FABP7,MOBP,DOCK10,SLC2A5,SHANK2,PHLDB1,WSCD1,CACNB2,CHRNB2,PACSIN1,POU3F4,KCNC1,PID1,ATN1,RGS10,SSPN,LMO1,ELAVL3" Drug 2310_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "GRAMD1B,CDC42BPA,ANK1,SHANK2,FGF17,WSCD1,PCSK2,PDE4B,GPR37L1,PIK3CD,SULT4A1,VAV2,PACSIN1,TOX,KCNMA1,RAB3IL1,RAD52,EN2,RASGRP2" Drug 2740_UP Pyrithyldione [77-04-3]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MAPT,FHL1,NLGN1,SLC6A9,DNAH17,ASPH,B3GALT2,NCAM1,ROBO3,GRIK2,LILRA4,HPSE2,PMP2,RGS6,KCNC1,KCND3,KCNMA1,FAM13C,ST8SIA3" Drug 4111_UP Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "EMID1,CEND1,ADORA3,DOCK10,GAS7,SORBS1,PKNOX2,ASPH,ATP1A2,GLS,ATF7,OPCML,PDE3B,SULT4A1,PARP11,ATN1,RGS10,SSPN,EFNA3" Drug 6465_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "FOXG1,C1orf61,APBA2,GAS7,SORBS1,ATP1A2,ZCCHC24,WWC1,GRM3,OPCML,HRH3,PRMT8,CHRNB2,SLC22A6,SULT4A1,TENM4,OSBPL3,KCND3,USH1C" Drug 2913_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MAPT,EMID1,ASIC4,FOXG1,ANK3,SLN,WDTC1,GNG3,BRSK2,INA,PDE2A,SCRG1,CHI3L2,UBTF,MASP1,SYTL2,SV2A,SEC61A2,ELAVL3" Drug 4407_UP Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "TUBB4A,KIAA1109,ANK1,BCAN,SLC2A5,MSR1,ZCCHC24,NPAS3,GPR162,WSCD1,OMG,OPCML,GPR37L1,PLCH2,MAPK8,RIMS3,KCND3,KCNH1,TMCC2" Drug 4355_UP Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "CDHR1,RYR1,ADORA3,KIAA1109,MOBP,APC,SLC1A7,SHANK2,TAGLN3,TNIK,NPAS3,AJAP1,GPM6A,TNS1,CDH8,PIK3CD,CNTN1,TENM4,STMN4" Drug 4958_UP Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "NDRG2,MOBP,APBA2,APC,CADM3,AJAP1,SLCO1C1,POPDC3,GNG4,OPCML,KCNK10,PDE3B,PDE4B,CHI3L2,PLCH2,TMCC2,SIDT2,ELAVL3,RASGRP2" Drug 4963_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ASIC1,NDRG2,FABP7,SLC2A5,SHANK2,SLCO1A2,SLN,ALDH1L1,GNG4,MYRF,WSCD1,ZEB1,SLC22A6,PACSIN1,RIMS3,ITIH2,KCND3,RGS10,SIDT2" Drug 5742_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "ABAT,EMID1,ADORA1,AGT,KIAA1109,RPH3A,ASTN1,CADM3,ZSWIM8,INKA2,VAMP1,NPPA,NEURL1,TNS1,PLEKHB1,PMP2,CRMP1,ITIH2,ABCC9" Drug 2705_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MAPT,SYNDIG1,ACTN2,ADORA1,TRIM46,ANK3,CSPG5,DNAH17,SORCS3,SNAP25,SCN3B,GLS,PRUNE2,NPPA,CHRNB2,KCNMA1,DLG3,SLC17A6,RASGRP2" Drug 1770_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MBP,TUBB4A,PDE8B,CADM3,ADGRB2,GLS,MYRF,CACNA1A,NPPA,OMG,NEURL1,KCNK10,LILRA4,DUSP26,COL9A2,PACSIN1,TMCC2,ATN1,DSCAM" Drug 4747_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "MAPT,ADORA1,MOBP,CDC42BPA,BCAN,NCAM1,NEUROD1,MLC1,GNG3,PAH,HPSE2,CHRNB2,PKN2,RIMS3,PTHLH,KCND3,SRGAP3,TMCC2,NUP214" Drug 4784_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.22E-04 1.00E+00 1.09E-02 1.19E-01 19 196 "EMID1,APBA2,APC,SYBU,SLC1A7,SLC14A1,TAGLN3,BRINP2,ATP1A3,GART,BTRC,CACNA1A,OPCML,NEURL1,PLEKHB1,CRMP1,VCAN,ITIH2,KCNMA1" Drug CID000107927 5-hydroxypropafenone Stitch 3.22E-04 1.00E+00 1.09E-02 1.19E-01 7 34 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug 1471_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.35E-04 1.00E+00 1.11E-02 1.22E-01 18 181 "F3,HPCAL4,SYBU,ZNF365,FYN,ZCCHC24,RGL1,ACSBG1,GLS,VAMP1,HAP1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3" Drug 6276_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.35E-04 1.00E+00 1.11E-02 1.22E-01 18 181 "ADD3,TUBB4A,SYBU,CCDC88A,GPR153,FYN,ZCCHC24,RGL1,ACSBG1,PADI2,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug CID000071157 nefiracetam Stitch 3.37E-04 1.00E+00 1.11E-02 1.22E-01 9 56 "ACHE,GAD2,NCAM1,CACNA1A,CACNA1E,GRIA1,CHRM1,CHRNB2,PRKACB" Drug ctd:D002217 Carbachol CTD 3.37E-04 1.00E+00 1.11E-02 1.22E-01 9 56 "ACHE,FGF1,FYN,NPPA,CHRM1,CHRM4,CHRNB2,PRKCZ,SYNC" Drug 6642_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "NDRG2,ADORA3,MOBP,TRIM46,NCAM1,COLGALT2,CELF3,LILRA4,TMPRSS5,CADM1,IFFO1,RGS6,PKN2,MAPK8,EDRF1,RIMS3,KCND3,ARNT2,RASGRF1" Drug 3867_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "CEND1,ADCY2,TUBB4A,MOBP,C1orf61,ANK1,APBA2,LMO3,GLS,POPDC3,ZEB1,CHRNB2,PIK3CD,CNTN1,NECAB2,CNIH3,ATN1,RGS10,ELAVL3" Drug 3793_UP Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ACTN2,SLC2A5,PKNOX2,ASCL1,PDE8B,CDK5R2,PRUNE2,OLR1,CA14,ZFYVE9,SPATA6,ARHGEF4,NOS1AP,PTAFR,PTPRZ1,DSCAM,DTNA,LMO1,RASGRP2" Drug 6842_UP Iopromide [73334-07-3]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "DPF1,NDRG2,KIAA1109,ASIC4,FHL1,FOXG1,ITSN1,ATP2B2,NEUROD1,CACNA1A,NUMA1,PLCH2,EDRF1,PTHLH,KCND3,KCNJ9,RABGAP1L,RAD52,ELAVL3" Drug 2720_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "SYNDIG1,ACTN2,MDM4,SYBU,RPH3A,DNAH17,SORCS3,ALDH1L1,PHLDB1,MYRF,BTRC,TGFBR3,CDH8,PDE2A,MASP1,STMN4,TMCC2,SUSD4,RGS10" Drug 5394_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "TTYH1,ADCY2,SEMA6A,MSR1,DLL3,ATP2B2,NMNAT2,RGL1,GLS,VAMP1,ZEB1,CAMK2G,SERPINE2,ARHGEF4,MAPK8,ITIH2,KCNMA1,SSPN,ELAVL4" Drug 3195_UP Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "MOBP,APC,SNAP25,FYN,MYT1L,ADGRL3,GRM3,TGFBR3,DAAM2,POU3F2,NOS1AP,PHYHIP,CNIH3,PRDM2,DTNA,NUP214,ST8SIA3,SSPN,VWA5A" Drug 4730_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "RYR1,ADORA1,ASIC4,RASA3,SYBU,BRINP2,B3GALT2,GPR162,ADGRL3,CACNA1A,GRIK2,SEZ6L,PTCH1,PTHLH,TMCC2,NAV2,ATN1,RBM12,RASGRP2" Drug 6137_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ASPH,B3GAT1,PRUNE2,WSCD1,ZEB1,TPM3,CHRNB2,MAPK8,PROX1,KCND3,ATN1,DSCAM,DTNA,CRTAC1,SIDT2,EFNA3,ELAVL3,LRRC23,RASGRP2" Drug 5519_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "FHL1,CDC42BPA,RASA3,APBA2,ZCCHC24,GAD2,EMC1,PHLDB1,ROBO3,GPM6B,NUCB1,GUCY1A2,CNTN1,MICAL1,PACSIN1,EDRF1,DSCAM,DTNA,ST8SIA3" Drug 5787_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "KIAA1109,PLA2G6,SLC1A7,EMC1,NPAS3,GPM6B,CACNB2,GRIK2,TF,INA,CELF3,CDH10,CHI3L2,IFFO1,TOX,KCNA2,KCND3,PID1,SEC61A2" Drug 4160_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "APBA2,GAS7,BCO1,PKNOX2,SHANK2,B3GAT1,ATP2B2,SOX10,NCAM1,WSCD1,CDC42,TPM3,ADGRG1,ARHGEF4,PTCH1,TMEM255A,RAD52,DSCAM,PAK5" Drug 6947_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "SEMA6A,SLC1A7,BCO1,SLC6A9,GPR153,ASTN1,KIF21B,ALDH1L1,ASTN2,KAZN,WSCD1,NUMA1,PLEKHB1,NMT2,CTNND2,EDRF1,GON4L,NAV2,LRRC23" Drug 3316_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "NDRG2,SLC1A7,DNAH17,GAD2,MYH7,ALDH1L1,INKA2,NEUROD1,AJAP1,ROBO3,NEURL1,PIK3CD,SULT4A1,MAGI2,PTPRD,CRTAC1,NUP214,USH1C,EN2" Drug 4979_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ASIC1,TUBB4A,SLC1A2,RPH3A,SLC1A7,WDTC1,GAD2,RND1,AJAP1,ASTN2,POPDC3,WSCD1,GPM6B,CACNB2,KCNK10,ITIH2,NUP214,SIDT2,ELAVL3" Drug 4760_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ASIC1,PKNOX2,SLC6A9,PDE8B,ATP2B2,NPAS3,GNG3,GPM6B,ZEB1,NUMA1,GRIK4,KCNK10,ASIC3,PKN2,PTAFR,PTHLH,KCND3,ELAVL3,RASGRP2" Drug 4097_DN Gelsemine [509-15-9]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "KIAA1109,APC,BCAN,SLC1A6,B3GAT1,ALDH4A1,ATP1A3,VAMP1,BRSK2,LILRA4,ARHGAP22,ZFYVE9,CCSER2,EDRF1,ITIH2,AK5,SLC6A15,ROM1,LRRC23" Drug 5915_UP rotenone; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "MDM4,TUBB4A,KIAA1109,SORBS1,EMC1,RND1,SEMA4A,NUMA1,TNS1,PTGDR2,MAPK8,MAPK10,SYNC,KCND3,RABGAP1L,RAB3IL1,TTLL7,SSPN,EFNA3" Drug 6380_UP STOCK1N-35215; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "MAPT,ACTN2,FGR,AMPH,DOCK10,BCAN,SNAP25,ADGRB2,ALDH1L1,GNG3,TNS1,PCDH9,TPM3,MAGI1,IFFO1,EDRF1,KCND3,ATN1,TTLL7" Drug 6622_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ACHE,FGF1,PLA2G6,PKNOX2,SHANK2,BRINP2,TNIK,ADAM15,PHLDB1,DAAM2,CHRNB2,JAM2,VAV2,SPATA6,CTNND2,DLG3,RASGRF1,DTNA,ELAVL3" Drug 2800_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "EMID1,NDRG2,SORBS1,PKNOX2,SHANK2,ZCCHC24,GAD2,PHLDB1,GLS,POPDC3,SEMA4A,SPATA6,CRMP1,ARHGEF4,PRDM2,KCNMA1,PARP11,ROM1,RCAN2" Drug 5633_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "HPCAL4,GPR153,ALDH4A1,RGL1,GPM6B,OMG,CCKBR,TNFRSF1B,TPM3,VAV2,MAPK8,NOS1AP,KCNC1,KCND3,KCNK2,ATN1,SIDT2,LMO1,RASGRP2" Drug 2188_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ADORA1,CDC42BPA,RASA3,AQP4,SLC1A6,PKNOX2,ASCL1,DLL3,SLN,WDTC1,NEUROD1,GPM6B,NPPA,GUCY1A2,SCRG1,POU3F2,SV2A,DSCAM,ELAVL3" Drug 6385_DN 5707885; Down 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "KIAA1109,MOBP,DOCK10,SORCS3,FYN,INKA2,GNG3,CELF3,PAX6,PDE4B,SLC22A6,POU3F2,SDC3,KCNMA1,RAB3IL1,L1CAM,NUP214,RAVER2,EPB41L1" Drug 2516_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "TUBB4A,KIAA1109,BCAR3,FHL1,SLCO1A2,ATP1A3,FXYD6,SPART,NCAM1,FGF17,GRIA1,NRXN1,POU3F2,TOX,PTAFR,ATN1,CAMK1G,ELAVL3,RPE65" Drug 4475_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ARID1A,C1orf61,SORBS1,SLC1A7,ZSWIM8,NFASC,GJB1,PHLDB1,GRIA4,PTGDR2,ARHGAP22,PIK3CD,VAV2,MICAL2,PLCH2,TOX,RIMS3,ATN1,DTNA" Drug 6180_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "EXTL1,ADORA1,BCO1,PDE8B,SLCO1A2,GAD2,NAP1L2,RAP1GAP2,BTRC,NPPA,GRIN1,ATP13A2,PTGDR2,SEZ6L,NOS1AP,SMG7,SSPN,ROM1,RASGRP2" Drug 6674_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "DPF1,ACHE,CEND1,MDM4,FOXRED2,PLA2G6,BCAS1,SLC1A7,NCAM1,PHLDB1,ADGRL3,DAAM2,SCRG1,CHRNB2,ZFYVE9,SULT4A1,VAV2,MED1,PTAFR" Drug 2191_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "RYR1,CDC42BPA,PDE8B,GPR153,DNAH17,DLL3,EMC1,FXYD6,NPAS3,CAMSAP2,NEURL1,MAGI1,CHRNB2,JAM2,ZFYVE9,EDRF1,KCNJ4,DLG3,BEND5" Drug 5974_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "SYNDIG1,ACTN2,FABP7,ASIC4,C1orf61,APBA2,BCAN,ZCCHC24,CADM3,ALDH1L1,GFAP,PHLDB1,GLS,NUMA1,PTGDR2,POU3F2,KCND3,DTNA,ELAVL3" Drug 3364_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "CEND1,FHL1,FOXG1,SORBS1,ATP1A3,ATP2B2,KIF21B,PHLDB1,AJAP1,ROBO3,GNG3,NEURL1,TNS1,SLC22A6,PTAFR,RABGAP1L,PARP11,NUP214,ELAVL3" Drug 3719_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "KIAA1109,MSR1,DNAH17,ATP2B2,GAD2,NPAS3,INKA2,CDK5R2,NPPA,GPR19,OPCML,TNS1,ZFYVE9,NECAB2,NOS1AP,RIMS3,NTM,RABGAP1L,ATN1" Drug 6445_UP Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "KIAA1109,SORBS1,PDE8B,ASPH,ZCCHC24,KIF21B,CDK5R2,WSCD1,CAMK2G,CHI3L2,CHRNB2,KIAA1549L,IFFO1,NSD2,SDC3,MAPK8,KCNMA1,RALGDS,RGS7" Drug 5703_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ASIC1,APC2,NDRG2,FHL1,RASA3,SLC2A5,PKNOX2,GPR153,NPAS3,GNG3,GNG4,PRUNE2,OPCML,MAPK8,MAGI2,ATN1,DTNA,PAK5,CAMK1G" Drug 2038_UP Danazol [17230-88-5]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "PDE8B,SLN,SNAP25,ADGRB2,ALDH1L1,GNG3,MYRF,CACNA1A,OMG,LILRA4,ZMYND8,CA14,DUSP26,CAMKV,PACSIN1,TMCC2,RAP1GAP,CAMK1G,NUP214" Drug 2735_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "FHL1,AMPH,ANK3,ASPH,CCDC181,CADM3,B4GALNT1,NEUROD1,ACSBG1,ROBO3,PRUNE2,TMEM257,BEST1,CTNND1,KCND3,KCNMA1,RASGRF1,FAM13C,EPB41L1" Drug 4097_UP Gelsemine [509-15-9]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "CEND1,NDRG2,C1orf61,PKP4,APC,PKNOX2,TNIK,NFASC,HAP1,NEURL1,SEZ6L,HPSE2,CADM1,PIK3CD,ARHGEF4,KCND3,DTNA,NUP214,RASGRP2" Drug 3192_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "FGF1,SEMA6A,APBA2,RPH3A,DLL3,CCDC181,INKA2,GLS,PRUNE2,HAP1,CCKBR,TGFBR3,PCSK2,NMT2,PHYHIP,CAMK1G,RERGL,RAVER2,RASGRP2" Drug 5605_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 1.11E-02 1.22E-01 19 197 "ARID1A,NDRG2,ADD3,APBA2,GAS7,WDTC1,ZCCHC24,SPART,ASTN2,SEMA4A,GNG3,CACNB2,GPR19,PSD3,MED1,PLPPR1,SMG7,SSPN,EFNA3" Drug ctd:D005473 Fluoxetine CTD 3.59E-04 1.00E+00 1.12E-02 1.23E-01 27 331 "SERPINA3,ADORA1,FGF1,PDE8B,GAD2,NCAM1,GFAP,GNAS,NRGN,NUCB1,GRIA1,GRIA2,GRIK2,KCNK10,DCLK1,PDE4B,PDYN,HAPLN2,PRKCG,MAPK8,HES5,KCNA6,KCNJ4,KCNK2,L1CAM,EFNA3,OLIG2" Drug CID006450546 gavestinel Stitch 3.59E-04 1.00E+00 1.12E-02 1.23E-01 6 25 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000024365 Multicide Stitch 3.59E-04 1.00E+00 1.12E-02 1.23E-01 6 25 "SCN4B,SCN3B,NKX6-2,PTPN5,ASIC3,HPR" Drug 2279_DN Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ARID1A,KIAA1109,FHL1,ZNF365,DNAH17,EMC1,INKA2,BTRC,TCF7L2,HAP1,ZMYND8,PIK3CD,CNTN1,EDRF1,HP1BP3,PARD6A,RAB3IL1,ATN1,SSPN" Drug 3663_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "HPCAL4,PPM1E,BRINP2,MYBPC1,NFASC,AJAP1,MLC1,GPM6B,CDC42,PADI2,CHRNB2,GDAP1L1,PIK3CD,NECAB2,IGSF1,RIMS3,PTPRD,ARNT2,PAK5" Drug 5453_UP Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ADORA1,DKK3,WDTC1,CADM3,ALDH1L1,ROBO3,GNG3,PRUNE2,OPCML,GUCY1A1,KCNK10,SLC22A6,DNAJC12,ARHGEF4,PTCH1,JAKMIP2,PTHLH,PTPRO,ABCC9" Drug 6627_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MAPT,EMID1,ADCY2,FGF1,NTNG1,B3GAT1,CCDC181,ATP1A2,ATP1A3,CADM3,GRIK2,NMT2,PROX1,PHYHIP,SMG7,KCND3,RAB3IL1,DTNA,VWA5A" Drug 4761_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ASIC1,TUBB4A,GPR153,FYN,AJAP1,SEMA4A,OMG,OPCML,USP2,CDH8,ZFYVE9,SULT4A1,PLPPR1,PTHLH,KCNH1,RAD52,VWA5A,ELAVL3,EPB41" Drug 6163_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ABAT,SYNDIG1,PLA2G6,PPM1E,BCAS1,SOX10,GAD2,ZSWIM8,BTRC,OPCML,SEZ6L,ZMYND8,PTCH1,DLG3,CAB39L,ATN1,EEF1A2,ELAVL4,RASGRP2" Drug 3509_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "DPF1,ADORA1,CDC42BPA,MSR1,PKNOX2,ATM,GAD2,SLCO1C1,MYRF,BTRC,PDE3B,ADGRG1,FADS2,SDC3,ITIH2,KCNJ4,TMCC2,RAB3IL1,DTNA" Drug 5387_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ASIC1,KIAA1109,FHL1,FOXG1,RASA3,SORBS1,MSR1,ATM,NEUROD1,ZEB1,PC,ADGRG1,SULT4A1,TOX,SYNC,TMCC2,ATN1,TTLL7,LMO1" Drug 5422_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ARID1A,PLA2G6,FHL1,SLC2A5,SHANK2,TAGLN3,ASPH,ZCCHC24,ALDH1L1,RGL1,SLCO1C1,POPDC3,PDE3B,SYNC,PTAFR,PTHLH,ELMO1,CNIH3,DTNA" Drug 4398_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ASIC1,NDRG2,SEMA6A,DOCK10,SLC1A2,SLC2A5,SLCO1A2,B3GAT1,KIF21B,NPAS3,MLC1,GRIN1,INA,CDH10,PDE1C,ASIC3,CRMP1,MAPK8,KCNC1" Drug 3450_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MAPT,BCAS1,ARHGAP5,B4GALNT1,SPART,GLS,BTRC,NRGN,TPD52,VAV2,MAPK8,SMG7,NAV2,DLG3,C12orf4,RAP1GAP,DSCAM,RGS10,SEC61A2" Drug 5409_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "DPF1,MAPT,ARID1A,NDRG2,HPCAL4,DOCK10,GAS7,MSR1,ASPH,GLS,VAMP1,GNG3,GPM6B,CAMK2G,GRM3,CNTN1,MAPK10,SYNC,PTHLH" Drug 3941_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ACTN2,ADCYAP1R1,RYR1,ADORA3,PLA2G6,SEMA6A,RASA3,SLITRK3,SLC1A7,PKNOX2,CSPG5,NMNAT2,NCAM1,NEUROD1,POU3F4,KCNK2,DNAH9,PARP11,RASGRP2" Drug 5406_UP Nizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "SYNDIG1,EXTL1,EYA1,KIAA1109,PLA2G6,FHL1,GAS7,ASPH,ZCCHC24,PRUNE2,GPM6A,CDC42,CDH10,PIK3CD,RGS6,PTAFR,PTHLH,RAD52,DTNA" Drug 2304_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ADCYAP1R1,ADORA1,ANK1,PKNOX2,TNIK,CADM3,SOX10,MYH7,SPART,GRIK2,GRIN1,GRM3,TNS1,SEZ6L,PDE1C,CHRNB2,PACSIN1,PTAFR,SLC17A6" Drug 4698_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "DPF1,ASIC1,CEND1,NDRG2,ADORA1,KIAA1109,PDE8B,ADAM15,CHRNB2,EDRF1,PTHLH,HP1BP3,KCNMA1,GNE,SIDT2,EFNA3,ROM1,EN2,RASGRP2" Drug 5727_UP Dienestrol [84-17-3]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MDM4,FGF1,TAGLN3,ALDH4A1,ALDH1L1,NDUFA5,VAMP1,SEMA4A,GNG4,BTRC,BRSK2,GRIK2,OPCML,PADI2,CHRM4,PTHLH,SV2A,DLG3,RGS10" Drug 3748_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "RTN1,FGF1,SLITRK3,PDE8B,BRINP2,ALDH1L1,RND1,GPM6B,ATF7,GRM3,PADI2,PCDH9,DCLK1,SULT4A1,SPATA6,PACSIN1,ATRNL1,PTCH1,RASGRF1" Drug 4004_UP Boldine [476-70-0]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MAG,LRRTM4,MOBP,ANK2,B3GALT2,ACSBG1,GNG3,BTRC,ADGRL3,GRIK2,PDE4B,IFFO1,MAPK10,PROX1,KCND3,DLG2,DTNA,CAMK1G,ST8SIA3" Drug 6025_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "CEND1,RYR1,AGT,ASIC4,SLC1A7,PDE8B,DDX25,ADGRB2,COLGALT2,GNAS,KCNK10,CAMKV,POU3F4,RIMS3,ITIH2,SV2A,SRGAP3,ATN1,CAMK1G" Drug 5682_UP Niridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "DPF1,ACTN2,NDRG2,PLA2G6,MOBP,C1orf61,SLC1A6,GAD2,FGF17,RND1,NPPA,CDH10,PACSIN1,VCAN,MAGI2,KCNJ4,SSPN,VWA5A,OLIG2" Drug 6142_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "TUBB4A,BCAR3,NTNG1,NLGN1,ZNF365,B3GALT2,NCAM1,INKA2,WWC1,WSCD1,GRIK2,TMPRSS5,BEST1,MASP1,PLPPR1,PTHLH,ATN1,DSCAM,SSPN" Drug 6689_UP Biotin [58-85-5]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MDM4,APC,ATP2B2,DKK3,EMC1,ATF7,TPM3,COL9A2,IFFO1,NSD2,POU3F2,CRMP1,MICAL2,MAPK8,HP1BP3,KCNJ4,DSCAM,EFNA3,EPB41" Drug 4099_DN Alprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "KIAA1109,FGF1,GAS7,NLGN1,SLC1A6,PDE8B,ATP1A3,SCN3B,ACSBG1,MYRF,CACNA1A,GPM6B,BRSK2,GRIK2,OPCML,SPATA6,TENM4,ATN1,RGS7" Drug 3743_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MAPT,SLC14A1,MLC1,GPM6B,NUMA1,TNS1,PDE3B,GON4L,PTCH1,CNIH3,SMG7,PARD6A,AK5,SUSD4,ATN1,BEND5,DTNA,SIDT2,ELAVL3" Drug 3307_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ADORA1,FHL1,FOXG1,ITSN1,APBA2,BCAN,SORBS1,SLC1A7,ATM,BCL2L2,NDUFA5,ARHGEF7,KAZN,PRUNE2,NUMA1,CDH10,PTGDR2,PTAFR,DTNA" Drug 2326_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ASIC1,EMID1,KIAA1109,MOBP,ANK3,ARHGAP5,ASPH,WDTC1,ALDH1L1,ROBO3,BTRC,SULT4A1,CRMP1,MAPK8,HP1BP3,RAD52,ATN1,EFNA3,VWA5A" Drug 3325_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MDM4,GRAMD1B,FOXRED2,FHL1,HPCAL4,SLN,CADM3,NEUROD1,WSCD1,OMG,PAX6,TNFRSF1B,PCDH9,PDE3B,SCRG1,SNCAIP,SRGAP3,NTM,ELAVL3" Drug 5972_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ACTN2,FABP7,ASIC4,APBA2,GAS7,BCAN,WDTC1,CADM3,EMC1,ALDH1L1,GFAP,CDC42,PTGDR2,PRMT8,POU3F2,KCND3,PEX5,ELAVL3,RASGRP2" Drug 6175_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "SYNDIG1,ACTN2,RYR1,APC,MSR1,GPR153,NPAS3,NFASC,GPR162,PSD3,PTGDR2,TUB,PARD6A,KCNJ9,TMCC2,DLG3,ATN1,RASGRF1,USH1C" Drug 1513_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "TESK2,CDC42BPA,SLC1A7,EMC1,ADAM15,GART,GLS,BTRC,GPR19,CAMK2G,UBTF,CCSER2,SULT4A1,CHD1L,SF1,MAPK8,DNAJC6,TMCC2,ROM1" Drug 3753_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ADORA1,ADORA3,CPLX2,GFRA1,RND1,GNG3,GRIN1,JAM2,SLC22A6,VAV2,SNCAIP,TOX,PTPRO,KCNJ4,ARNT2,RAD52,ATN1,RASGRF1,EFNA3" Drug 3134_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MOBP,C1orf61,CDC42BPA,ANK3,SLC1A7,GPR153,TAGLN3,ALDH4A1,NCAM1,ALDH1L1,CDK5R2,CACNB2,PADI2,CTNND2,ITIH2,SV2A,PAK5,TTLL7,LRRC23" Drug 426_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "NDRG2,TUBB4A,PLA2G6,APC,SLC2A5,PKNOX2,NMNAT2,ADAM15,RAP1GAP2,ALDH1L1,ARHGEF7,TMPRSS5,PFKFB3,CHRM4,CCSER2,VAV2,ITIH2,SIDT2,EPB41L2" Drug 2768_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "DPF1,NDRG2,RTN1,ADORA1,PKNOX2,PDE8B,ALDH4A1,NPAS3,PTGDR2,TPM3,CHI3L2,CHRNB2,ZFYVE9,SDC3,ARHGEF4,PSMD13,PRDM2,NUP214,ELAVL3" Drug 3390_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ADCY2,FABP7,TUBB4A,KIAA1109,PLA2G6,MOBP,CDC42BPA,BCAN,RPH3A,SLCO1A2,TAGLN3,FYN,GNG4,OMG,CHRNB2,TENM4,MASP1,PTAFR,PTPRD" Drug 5645_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "EMID1,MOBP,DOCK10,SLC1A7,SLC2A5,BRINP2,SEMA4A,ADGRL3,WSCD1,ACSL6,CRB1,CELF3,NOS1AP,PTAFR,KCNK2,ATN1,DSCAM,SIDT2,VWA5A" Drug 7380_UP Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ABAT,MOBP,CDC42BPA,AQP4,PDE8B,ATP1A3,TNIK,ALDH1L1,PHLDB1,ASTN2,GNG3,BTRC,GPM6B,RBFOX2,CADM1,SDC3,PTCH1,ATN1,RGR" Drug 6019_UP Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ACHE,ACTN2,WLS,TUBB4A,FGF1,FHL1,MOBP,SYBU,EMC1,ALDH1L1,ZEB1,NEURL1,CDH8,PDE3B,VAV2,SYNC,DSCAM,NUP214,ST8SIA3" Drug 6033_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "CEND1,HPCAL4,RASA3,SLC1A2,SLC1A7,BCO1,TAGLN3,INKA2,GJB1,ATF7,KCNK10,TNS1,CHI3L2,SULT4A1,MICAL1,CNIH3,PRDM2,RCAN2,RASGRP2" Drug 3525_UP Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "KIAA1109,CDC42BPA,APBA2,NLGN1,SLC14A1,TAGLN3,ATP1A3,CADM3,NPAS3,NEUROD1,GLS,KAZN,GNAS,ZEB1,GRM3,NEURL1,TNS1,CHD5,RAD52" Drug 5512_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ACTN2,NDRG2,AGT,MOBP,SLCO1A2,SLN,CADM3,GPR162,GNG3,WSCD1,ACOT7,NLGN3,SNCAIP,RGS6,EDRF1,KCND3,NUP214,SIDT2,VWA5A" Drug 3174_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ARID1A,FHL1,C1orf61,MSR1,SHANK2,SNAP25,CCDC181,ATP2B2,MYT1L,NPAS3,PHLDB1,NEURL1,PDE3B,MAPK10,PROX1,NTM,DPP6,TTLL7,VWA5A" Drug 6263_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "KIAA1109,PLA2G6,SYBU,ASTN2,SEMA4A,GPM6A,GPR19,NUMA1,NEURL1,CHRNB2,VCAN,SDC3,KCNK1,DSCAM,BSDC1,NUP214,RGS10,EFNA3,EPB41L1" Drug 376_DN raloxifene hydrochloride; Down 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ARID1A,NDRG2,FOXRED2,ASIC4,NSG2,ASCL1,GAD2,ZSWIM8,MYH7,EMC1,GRIN1,OPCML,JAM2,IFFO1,DZIP3,SRGAP3,KCNJ10,SUSD4,SIDT2" Drug 4393_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "ASIC1,TUBB4A,KIAA1109,HPCAL4,SLC2A5,ASCL1,SNAP25,NCAM1,NEURL1,KCNK10,TNS1,PDE1C,GPR37L1,VCAN,NOS1AP,CNIH3,SRGAP3,KCNMA1,RASGRP2" Drug 7421_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "PLA2G6,SEMA6A,SLC2A5,ALDH4A1,ZCCHC24,B4GALNT1,EMC1,GNG3,ATF7,RBFOX2,PDE1C,PLEKHB1,ZFYVE9,VCAN,DZIP3,RIMS3,PEX5,DTNA,ABI2" Drug 6707_UP Propofol [2078-54-8]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "APC,SLC6A9,SOX10,ZSWIM8,CNTN2,GPR19,BRSK2,OPCML,TNS1,CHI3L2,ARHGAP22,SULT4A1,COL9A2,CRMP1,RGS6,IGSF1,PROX1,ATN1,RASGRP2" Drug 6487_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "RYR1,PKNOX2,SLC6A9,B3GAT1,CCDC181,B3GALT2,CADM3,CAMK2G,PSD3,TNS1,HRH3,SEZ6L,PDE4B,HPSE2,SNCAIP,HP1BP3,KCND3,ATN1,DTNA" Drug 2358_UP Flutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.66E-04 1.00E+00 1.12E-02 1.23E-01 19 198 "MDM4,ADORA1,TUBB4A,MOBP,C1orf61,ANK2,BCAN,CADM3,VAMP1,MYRF,NPPA,PSD3,CHRNB2,PPP2R5C,PTAFR,PEX5,ST8SIA3,SIDT2,ABI2" Drug ctd:D020849 Raloxifene Hydrochloride CTD 3.75E-04 1.00E+00 1.14E-02 1.25E-01 55 860 "SERPINA3,RBM10,F3,ADCY2,KLRC4,RYR1,AGT,FHL1,SFPQ,ANK3,TACC2,SYBU,BCAS1,CLSTN1,SLC1A2,SLIT1,SLN,BRINP2,RCOR3,PALLD,SON,MYT1L,TNIK,ZCCHC24,AHCYL1,ADGRB2,RGL1,KAZN,MMD2,WWC1,ZEB1,PCDHGA3,PDE3B,PDYN,ADGRG1,HMGB1,PFKFB3,SERPINE2,FLRT1,PMS2,MICAL2,OSBPL3,PRKCZ,PTPRE,ARNT2,NAV2,PEX5,KLRC2,KLRC3,RASGRF1,RET,RGS10,PHC2,ROM1,RCAN2" Drug ctd:D014403 Tubocurarine CTD 3.80E-04 1.00E+00 1.14E-02 1.25E-01 10 69 "ACHE,SLITRK1,CAPRIN2,EML4,CHRNB2,CNTN1,FEZ1,ATRNL1,LRRTM3,DSCAM" Drug CID000164810 kainite Stitch 3.89E-04 1.00E+00 1.14E-02 1.25E-01 7 35 "GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,MAPK10" Drug CID000127504 R 61837 Stitch 3.89E-04 1.00E+00 1.14E-02 1.25E-01 7 35 "FOXM1,SLC14A1,ROBO3,CACNA1A,ANLN,KCNA1,ELAVL4" Drug CID000011711 ethyldichloroarsine Stitch 3.89E-04 1.00E+00 1.14E-02 1.25E-01 7 35 "EYA1,SLC1A2,SLC1A6,SLC1A7,ADGRB2,PTPN5,NOS1AP" Drug CID000133240 N-propanoylmannosamine Stitch 3.89E-04 1.00E+00 1.14E-02 1.25E-01 7 35 "ST3GAL3,ST8SIA1,NCAM1,ST8SIA5,NTM,L1CAM,ST8SIA3" Drug 6132_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ABAT,WLS,AMPH,CDC42BPA,SORBS1,SHANK2,SLC14A1,GAD2,NPAS3,BTRC,WWC1,KCNK10,PHYHIP,PLPPR1,CNIH3,KCND3,SV2A,EEF1A2,SSPN" Drug 1893_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "CEND1,ADORA1,TMEM156,ANK3,SHTN1,SLC1A7,ASCL1,ATM,RAP1GAP2,TCF7L2,TGFBR3,REPS2,PDE3B,ZMYND8,TMPRSS5,KIAA1549L,CRMP1,TMCC2,NUP214" Drug 3636_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "SYNDIG1,KIAA1109,ASIC4,MOBP,DOCK10,PKNOX2,SHANK2,GPR153,CSPG5,BRINP2,ALDH1L1,RND1,CACNB2,SPX,PTCH1,KCND3,TMCC2,TTLL7,EN2" Drug 5426_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "DPF1,ASIC1,MAPT,FOXG1,SELL,ZCCHC24,GLS,CACNA1A,OMG,CELF3,PDE1C,ADGRG1,CRMP1,VCAN,MAPK10,RAD52,ATN1,FAM13C,VWA5A" Drug 3842_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "TUBB4A,SEMA6A,CDC42BPA,AQP4,BRINP2,ATP2B2,AJAP1,POPDC3,MYRF,WSCD1,ZEB1,CAMK2A,NUMA1,GRM3,OMG,INA,SLC22A6,ATN1,LMO1" Drug 7163_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "KIAA1109,ALDH4A1,ATM,PHLDB1,SEMA4A,PRUNE2,GPM6B,NEURL1,CDC42,CA14,GON4L,PTAFR,RABGAP1L,PEX5,RAD52,DSCAM,NUP214,ST8SIA3,SSPN" Drug 2287_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "WLS,FHL1,CDC42BPA,APBA2,GAS7,SORBS1,EMC1,SPART,ALDH1L1,INKA2,SEMA4A,TNS1,DZIP3,MAPK8,MAPK10,PEX5,NUP214,EFNA3,VWA5A" Drug 5783_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "MBP,SYNDIG1,NDRG2,FOXRED2,HPCAL4,SLCO1A2,TAGLN3,CCDC181,GAD2,ACSBG1,BTRC,PRUNE2,CACNB2,OMG,USP2,ZMYND8,ZFYVE9,PTPRD,KCND3" Drug 6249_DN Thiorphan [76721-89-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "F3,FOXRED2,SFPQ,CDC42BPA,TACC2,ATM,FYN,ZSWIM8,FAM168A,GNG4,PADI2,CCSER2,MED1,SF1,FEZ1,DNAJC6,RABGAP1L,WIPF2,ARHGEF10L" Drug 4539_UP Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "MAPT,KIAA1109,FGF1,FOXG1,APBB1,GAS7,SLC2A5,ASCL1,BRINP2,GPM6B,ZEB1,PTGDR2,ASIC3,CHD5,MAPK10,EDRF1,PROX1,STMN4,KCND3" Drug 3249_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "MDM4,NDRG2,F3,CDC42BPA,PPM1E,APC,ZNF365,SLC2A5,BCO1,PKNOX2,CCDC88A,SLN,GNG4,NUMA1,CAMKV,CNTN1,ARHGEF4,EDRF1,RAD52" Drug 1489_UP Antipyrine [60-80-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "EMID1,F3,PLA2G6,FHL1,MOBP,CDC42BPA,APC,BCAS1,SLC2A5,NEUROD1,VAMP1,NUMA1,OPCML,KCNK10,SULT4A1,SF1,DZIP3,SSPN,LRRC23" Drug 4338_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ADORA3,SLC1A6,PKNOX2,GAD2,ZSWIM8,NFASC,RND1,GPR19,SEZ6L,CA14,SULT4A1,NECAB2,SF1,SNCAIP,ITIH2,PTPRE,RAD52,RET,RLBP1" Drug 5094_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "PAQR6,NDRG2,RYR1,FOXRED2,SCN3A,SORBS1,SLC2A5,ASCL1,PDE8B,DNAH17,SOX10,LMO3,NEUROD1,GPM6B,SEZ6L,ZMYND8,CTNND2,PRDM2,FAM13C" Drug 370_DN troglitazone; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "CDC42BPA,SHANK2,ATP1A2,KAZN,TCF7L2,NEURL1,RBFOX2,PDE1C,PHKG1,KIAA1549L,TJP2,MAPK10,ECE2,MASP1,PLPPR1,KCNA1,PARD6A,RALGDS,DTNA" Drug 3402_UP Primidone [125-33-7]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "SYNDIG1,ADCY2,RYR1,RPH3A,DLL3,VAMP1,WSCD1,GPM6A,CCKBR,SEZ6L,PDE2A,GPR37L1,IFFO1,SNCAIP,PTHLH,KCNMA1,RAD52,ATN1,ELAVL3" Drug 7465_UP Spaglumic acid [4910-46-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "PAQR6,SEMA6A,APC,SLC1A7,DNAH17,WDTC1,SEMA4A,PSD3,NEURL1,CDC42,MAGI1,CHRNB2,SERPINE2,VAV2,SDC3,DTNA,NUP214,ROM1,EPB41L1" Drug 6053_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ASIC1,NDRG2,ADCY2,ADORA1,PLA2G6,APBA2,GAS7,NLGN1,PKNOX2,SLN,GAD2,NCDN,VAMP1,BTRC,ZEB1,CRMP1,MAGI2,NUP214,EFNA3" Drug 4777_UP Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "FHL1,SORBS1,SLC2A5,GPR153,WDTC1,CADM3,GNAS,BTRC,GRIN1,OPCML,TGFBR3,PDE3B,ADGRG1,FADS2,CNTN1,CRMP1,PARP11,EFNA3,VWA5A" Drug 4635_DN Androsterone [53-41-8]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "FOXRED2,APC,SLC1A7,PDE8B,ATP1A3,FYN,CADM3,ADGRB2,NEUROD1,GPM6B,GPR37L1,CHI3L2,PLEKHB1,CABP1,ARHGEF4,STMN4,RABGAP1L,RGS10,LRRC23" Drug 6076_UP Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "C1orf61,ANK1,AQP4,RPH3A,SLC2A5,PKNOX2,TAGLN3,PRUNE2,HAP1,PSD3,HRH3,SEZ6L,HPSE2,SNCAIP,PSD,CA10,KCNMA1,ATN1,RASGRF1" Drug 583_UP HNMPA-(AM)3; Up 200; 5uM; PC3; HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "SERPINA3,ABAT,NDRG2,PKNOX2,DLL3,SPART,GLS,GRIA4,TF,PC,ARHGAP19,CA14,TUB,CADM1,ECE2,PTHLH,ITIH2,ATN1,USH1C" Drug 3675_UP Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "NTNG1,TAGLN3,IGSF9B,LMO3,MLC1,ASTN2,GPM6A,OMG,USP2,TPM3,PDE2A,PDE4B,CHRNB2,MICAL1,POU3F4,MED1,PTPRO,KCNJ4,NKAIN1" Drug 5499_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "SEMA6A,BCAN,SLC1A7,MSR1,SLN,SEMA4A,GPM6B,PSD3,GRIN1,OPCML,ZMYND8,PLEKHB1,KIAA1549L,MICAL1,PACSIN1,FEZ1,DTNA,PAK5,RASGRP2" Drug 5920_UP rotenone; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "MAPT,SLC1A6,SLC1A7,SLN,NPAS3,KAZN,GNAS,GNG3,BTRC,NUMA1,TF,MAGI1,CHI3L2,SPATA6,SMG7,DNM2,ARHGEF10L,LMO1,EN2" Drug 5637_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ACTN2,ADORA1,AQP4,PDE8B,FYN,WDTC1,GAD2,NEUROD1,HAP1,CAMK2G,TGFBR3,CDH8,PDE1C,CHRNB2,FADS2,SULT4A1,DTNA,EFNA3,ELAVL3" Drug 4778_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "EMID1,AQP4,SLC1A7,SLC2A5,SLC6A9,ASCL1,BTRC,ADGRL3,CACNA1A,WSCD1,TGFBR3,DUSP26,CABP1,MICAL1,NOS1AP,CNIH3,KCND3,KCNMA1,EFNA3" Drug 5423_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ARID1A,ADCY2,PLA2G6,FHL1,MOBP,CDC42BPA,DOCK10,GAS7,NPAS3,NEUROD1,CAMK2G,PDE1C,PDE3B,ZFYVE9,OSBPL3,PLCH2,ARHGEF4,RIMS3,DTNA" Drug 3744_DN Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "FGF1,APC,ALDH4A1,BTRC,CACNB2,PC,PLEKHB1,PIK3CD,CNTN1,CHD1L,SF1,VCAN,PTCH1,RAD52,SUSD4,ATN1,DTNA,SIDT2,EN2" Drug 223_DN TTNPB; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "EMID1,CDC42BPA,APBA2,SON,MYRF,ATF7,REPS2,TNS1,PCDH9,CHRNB2,CADM1,BEST1,FEZ2,ECE2,PTHLH,KCNK1,BEND5,SIDT2,EFNA3" Drug 7414_UP Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ARID1A,SYBU,BCAS1,SLC1A7,PKNOX2,B4GALNT1,RGL1,PHLDB1,GLS,BTRC,GPR19,PDE3B,SERPINE2,FADS2,CRMP1,ARHGEF4,PTPRE,NAV2,ELAVL4" Drug 4608_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ABAT,KIAA1109,CDC42BPA,RASA3,APBB1,ASTN2,GNG4,ADGRL3,GPM6B,NPPA,TLL2,CABP1,RIMS3,PRDM2,AK5,RASGRF1,DTNA,SIDT2,RCAN2" Drug 6401_DN F0447-0125; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "TTYH1,PKP4,CGREF1,SCN3B,SOX10,NFASC,PHLDB1,GPM6A,USP2,TNS1,ZMYND8,SDC3,CTNND2,PROX1,DSCAM,ABCC9,RGS7,VWA5A,LPAR6" Drug 6379_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "DPF1,RYR1,FGF1,PKP4,BCAS1,ASPH,EMC1,CPLX2,GPM6A,GPR17,ASIC3,COL9A2,NECAB2,RIMS3,CNIH3,KCND3,DSCAM,DTNA,USH1C" Drug 267_DN genistein; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "EMID1,SYNDIG1,ANK2,GAS7,ASCL1,CADM3,NPPA,CAMK2A,GRIN1,SEZ6L,ADGRG1,CHRNB2,JAM2,SULT4A1,CRMP1,CHD5,RAD52,ATN1,L1CAM" Drug 3320_UP Nitrofural [59-87-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ASIC4,FHL1,CDC42BPA,APBA2,APC,NLGN1,SLC1A7,ATM,INKA2,GNG4,DAAM2,ZFYVE9,SULT4A1,POU3F2,MAPK8,PLPPR1,NTM,KCNMA1,RAD52" Drug 4836_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "FHL1,C1orf61,MSR1,CCDC88A,ATM,KIF21B,NDUFA5,AJAP1,HAP1,PSD3,NEURL1,CDH8,SULT4A1,PACSIN1,NOS1AP,ITIH2,MAGI2,NAV2,EFNA3" Drug 5975_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ASIC4,APBA2,GAS7,EMC1,GFAP,WSCD1,CAMK2G,DAAM2,PTGDR2,PIK3CD,PACSIN1,POU3F2,ARHGEF4,RIMS3,ITIH2,KCND3,RAB3IL1,VWA5A,RASGRP2" Drug 5789_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "MAPT,PLA2G6,SELL,SLC14A1,PDE8B,ASPH,ALDH4A1,FYN,FAM168A,GPR19,KIAA1549L,PRDM2,PTPRE,PARD6A,AK5,RALGDS,BEND5,RGS7,ARHGEF10L" Drug 2139_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "PKNOX2,GPR153,CADM3,SOX10,ALDH1L1,CAMSAP2,BTRC,ATF7,ATP13A2,USP2,KCNK10,PCDH9,RBFOX2,CABP1,KLK6,PTAFR,DLG3,PID1,EEF1A2" Drug 4775_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "CDC42BPA,ZNF365,SLC1A7,SLC14A1,GPR153,TAGLN3,ASPH,ALDH4A1,NCAM1,ZEB1,PDE4B,OSBPL3,MAGI2,PTPRD,KCND3,KCNMA1,SIDT2,EFNA3,ELAVL3" Drug 3561_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "ACTN2,NDRG2,FGF1,ANK1,DOCK10,BRINP2,TNIK,ALDH1L1,NEUROD1,SLCO1C1,GLS,KAZN,WSCD1,MAPK10,JAKMIP2,STMN4,RAD52,ATN1,EFNA3" Drug 5505_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "PAQR6,ACTN2,KCNIP2,FHL1,SYBU,RPH3A,PKNOX2,SHANK2,NCAM1,WSCD1,GPM6A,NPPA,INA,P2RX7,NEURL1,ASIC3,FADS2,MAPK10,NOS1AP" Drug 1399_DN Isoniazid [54-85-3]; Down 200; 29.2uM; HL60; HG-U133A Broad Institute CMAP Down 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "TESK2,CDC42BPA,ANXA7,GAS7,URGCP,SON,WDTC1,EMC1,ADAM15,ALDH1L1,GLS,SEMA4A,NRGN,DNAJC12,PTPA,MAPK10,RAP1GAP,RFX5,SIDT2" Drug 7214_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "DPF1,ARID1A,APBA2,PDE8B,SLN,SOX10,ALDH1L1,PHLDB1,GLS,ATF7,DAAM2,CNTN1,SDC3,MAPK8,PEX5,RAD52,RALGDS,SSPN,RASGRP2" Drug 4962_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "APC2,CEND1,ADCY2,ADORA1,KIAA1109,SEMA6A,PKNOX2,BRINP2,WDTC1,RGL1,POPDC3,GNG4,GPM6B,LILRA4,CNTN1,PTPRO,DLG3,SIDT2,ELAVL3" Drug 6072_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "NDRG2,RYR1,FHL1,FOXG1,GAS7,RPH3A,MYT1L,PHLDB1,ACSBG1,VAMP1,SEMA4A,HAP1,GRIK3,ETNPPL,MAPK8,SYNC,PTHLH,CNIH3,RASGRP2" Drug 5754_UP Cromolyn disodium salt [15826-37-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-04 1.00E+00 1.14E-02 1.25E-01 19 199 "KIAA1109,FOXG1,C1orf61,APBB1,APC,SLC1A7,ALDH1L1,NDUFA5,SEMA4A,PRUNE2,OPCML,USP2,PADI2,NECAB2,MAPK10,RIMS3,SV2A,RGS10,RAVER2" Drug CID000002826 pseudococaine Stitch 3.94E-04 1.00E+00 1.15E-02 1.26E-01 40 570 "ABAT,ASIC1,ADCY2,RXRG,SCN3A,SCN4B,SCNN1D,FGF1,ACTL6B,ASIC4,MOBP,FOXM1,SLC1A2,SLC1A6,SLC1A7,ATP2B2,SCN3B,SALL3,SYT4,NPPA,ZEB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PDYN,ASIC3,CHRM1,CHRNB2,JAM2,PIK3CD,PTHLH,PARD6A,SLC17A6,NUP214" Drug CID005961627 PPNDS Stitch 4.08E-04 1.00E+00 1.19E-02 1.31E-01 5 17 "GRIA1,GRIA2,GRIA4,GRM3,P2RY12" Drug 4369_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.09E-04 1.00E+00 1.19E-02 1.31E-01 18 184 "NDRG2,FABP7,GPR153,CADM3,ALDH1L1,AJAP1,ACSBG1,POPDC3,KAZN,USP2,GUCY1A2,TNS1,PIK3CD,DNAJC12,CNTN1,NOS1AP,PTHLH,DTNA" Drug CID000005620 spiradoline Stitch 4.12E-04 1.00E+00 1.19E-02 1.31E-01 8 46 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,PDYN,ASIC3" Drug 7329_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "EMID1,NDRG2,C1orf61,SYBU,PKNOX2,NDUFA5,SEMA4A,PDE4B,ADGRG1,CHRNB2,RGS6,NCAN,MAPK10,PARD6A,RABGAP1L,ATN1,DSCAM,EFNA3,VWA5A" Drug 5603_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "NDRG2,FOXRED2,FOXG1,GAS7,PDE8B,GPR153,ZCCHC24,ALDH1L1,PHLDB1,VAMP1,TGFBR3,KCNK10,PC,TNS1,PDE3B,VAV2,PLPPR1,MAGI2,SMG7" Drug 2573_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "ABAT,MDM4,ANK3,PKP4,SLC1A7,GPR153,ASPH,BCL2L2,NEUROD1,RBFOX2,ZMYND8,CHRNB2,SPATA6,PKN2,EDRF1,PSMD13,MAGI2,KCND3,ABI2" Drug 3825_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "CEND1,SORBS1,AQP4,ASCL1,SLN,CCDC181,ALDH1L1,GFRA1,SEMA4A,NUMA1,GRIA4,PTGDR2,SEZ6L,CHI3L2,CABP1,SPATA6,ATN1,DTNA,ABCC9" Drug 3057_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "APC2,SEMA6A,ANK2,B3GAT1,PALLD,CRB1,PTGDR2,SEZ6L,PMP2,KLK6,PMEPA1,KCNC1,NTM,RAB3IL1,CRTAC1,ST8SIA3,RGS10,OLIG2,EPB41" Drug 6687_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "MDM4,MOBP,SNAP25,ATP1A3,INKA2,BTRC,OMG,CHI3L2,CAMKV,IFFO1,MICAL2,MAPK8,TOX,RIMS3,PRDM2,KCNC1,KCND3,AK5,ABCC9" Drug 2542_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "ACTN2,ARID1A,KIAA1109,FHL1,SLN,ALDH4A1,TNIK,SOX10,GAD2,TCF7L2,SEZ6L,ZMYND8,NMT2,CCSER2,PTAFR,ITIH2,DLG3,ATN1,BEND5" Drug 3014_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "MAPT,NDRG2,ADORA3,MOBP,C1orf61,TAGLN3,ATP2B2,MYBPC1,GNAS,GNG4,WSCD1,CACNB2,CHI3L2,ZFYVE9,CTNND1,PROX1,KCND3,LRRC23,RASGRP2" Drug 6128_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "EYA1,ADCY2,RYR1,BCAR3,HPCAL4,C1orf61,APBA2,APC,ZNF365,ALDH4A1,PALLD,KAZN,WWC1,GPM6B,ATP13A2,TJP1,VAV2,PSD,RIMS3" Drug 5391_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "ASIC1,ARID1A,PLA2G6,FHL1,SLITRK3,NPAS3,SLCO1C1,MLC1,BTRC,GPM6A,GPM6B,CAMK2G,USP2,ZFYVE9,NOS1AP,RIMS3,NTM,TMCC2,ATN1" Drug 2713_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "MAPT,MBP,SORBS1,SHANK2,GPR153,CCDC181,ACSBG1,BTRC,GPM6B,GRIN1,FLRT1,CNTN1,NECAB2,SPATA6,POU3F2,RIMS3,CNIH3,KCNK1,ABCC9" Drug 4073_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "EMID1,SLC2A5,SLC14A1,BRINP2,SORCS3,TNIK,ADGRB2,NPAS3,GNG4,USP2,NEURL1,PDE2A,JAM2,CADM1,MICAL2,CHD5,MASP1,PTCH1,SIDT2" Drug 4086_UP Trimethadione [127-48-0]; Up 200; 28uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "CEND1,ACTN2,AGT,AQP4,RPH3A,TAGLN3,TNIK,NCAM1,VAMP1,GPR17,KCNK10,TNS1,CDH8,PDE4B,MICAL2,RIMS3,DTNA,VWA5A,RASGRP2" Drug 416_DN clozapine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "SYNDIG1,TUBB4A,GAS7,DGKD,ASCL1,ZSWIM8,NMNAT2,SPART,KAZN,OPCML,NEURL1,CAMKV,CRMP1,ECE2,DSCAM,CAMK1G,USH1C,SEC61A2,ABI2" Drug 6049_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.15E-04 1.00E+00 1.19E-02 1.31E-01 19 200 "TUBB4A,KIAA1109,SEMA6A,HPCAL4,AMPH,GAS7,SLC2A5,CCDC88A,DLL3,ASTN1,WDTC1,TGFBR3,P2RX7,NECAB2,PLCH2,RIMS3,ITIH2,STMN4,KCNMA1" Drug CID000129400 K-II Stitch 4.21E-04 1.00E+00 1.21E-02 1.33E-01 12 96 "MAPT,ACHE,RPH3A,SNAP25,ADHFE1,CNDP1,CACNA1E,CAMK2A,CAMK2G,GRIA1,ATP13A2,NUP214" Drug CID000446755 P-NE Stitch 4.25E-04 1.00E+00 1.22E-02 1.34E-01 17 169 "ADORA1,ADORA3,ASCL1,PDE8B,NAP1L2,NCAM1,GNAS,CNDP1,NPPA,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,SERPINE2,CABP1,PRKACB" Drug 1793_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.25E-04 1.00E+00 1.22E-02 1.34E-01 17 169 "EPS8,TESK2,CCDC88A,FYN,PALLD,TNIK,ZCCHC24,RGL1,GLS,EML4,PCDH9,SERPINE2,DNAJC12,SYTL2,DNAJC6,TTLL7,EFNA3" Drug CID000005022 phenylisopropyladenosine Stitch 4.28E-04 1.00E+00 1.23E-02 1.35E-01 10 70 "ADAR,ADARB2,ADORA1,ADORA3,GPR162,PDE3B,PDE4B,CHRM1,PRKACB,KCNA6" Drug ctd:D001565 Benzoates CTD 4.30E-04 1.00E+00 1.23E-02 1.35E-01 4 10 "GRIA1,GRIA2,GRIA4,GRIK2" Drug CID000010443 dicyanimide Stitch 4.30E-04 1.00E+00 1.23E-02 1.35E-01 4 10 "HPS5,PMP2,PTHLH,SRGAP3" Drug 5908_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.37E-04 1.00E+00 1.25E-02 1.37E-01 18 185 "DPF1,ABAT,MAPT,TESK2,SH3GL2,SORBS1,FYN,RGL1,RND1,GLS,USP2,ACOT7,PIK3CD,DNAJC12,KIAA0513,PLPPR4,SRGAP3,EFNA3" Drug 6971_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.37E-04 1.00E+00 1.25E-02 1.37E-01 18 185 "MAPT,SELL,AMPH,SLC1A7,SLC2A5,DNAH17,FYN,AJAP1,PDE3B,PFKFB3,KLK6,NAV2,RAP1GAP,ZNF248,EFNA3,ROM1,EPB41L1,RASGRP2" Drug CID000062790 ED20 Stitch 4.41E-04 1.00E+00 1.26E-02 1.38E-01 9 58 "MAG,NCAM1,MLC1,GRIA1,OPCML,PAX6,PROX1,SV2A,NTM" Drug CID000001330 DPSPX Stitch 4.51E-04 1.00E+00 1.28E-02 1.41E-01 6 26 "ADAR,ADARB2,ADORA1,ADORA3,AGT,PDE3B" Drug CID000177965 T-440 Stitch 4.51E-04 1.00E+00 1.28E-02 1.41E-01 6 26 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000127736 desethyl KBT-3022 Stitch 4.51E-04 1.00E+00 1.28E-02 1.41E-01 6 26 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000104962 C6H12NO5P Stitch 4.66E-04 1.00E+00 1.33E-02 1.45E-01 7 36 "GAD2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000073960 glutamic acid diethyl ester Stitch 4.66E-04 1.00E+00 1.33E-02 1.45E-01 7 36 "ABAT,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000007464 4-isopropylaniline Stitch 4.81E-04 1.00E+00 1.36E-02 1.50E-01 10 71 "ACHE,ADGRV1,ADCY2,AGT,GNAS,NPPA,CHRM1,PRKACB,KCNA2,KCNA4" Drug CID000003140 D-N-Q Stitch 4.84E-04 1.00E+00 1.37E-02 1.51E-01 11 84 "ADORA1,GAD2,NUCB1,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,PDYN" Drug CID000482140 5'-pCAA-3' Stitch 4.94E-04 1.00E+00 1.40E-02 1.54E-01 14 126 "RYR1,FGF14,APC,SLC14A1,ATM,CACNA1A,GPM6A,PC,PRKCG,MAPK8,MAPK10,HP1BP3,KCNN3,ATN1" Drug 2474_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.97E-04 1.00E+00 1.40E-02 1.54E-01 18 187 "ANK2,NCAM1,INKA2,RGL1,CAMSAP2,ATP13A2,PADI2,PCDH9,ZFYVE9,SULT4A1,FEZ1,KIAA0513,RIMS3,DNAJC6,BEND5,TTLL7,ABI2,LPAR6" Drug 7368_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.97E-04 1.00E+00 1.40E-02 1.54E-01 18 187 "TESK2,APBB1,MADD,PDE8B,TAGLN3,ALDH1L1,PHLDB1,NUMA1,PSD3,TF,TNS1,CHRNB2,SDC3,SYTL2,PTHLH,ARNT2,DSCAM,EFNA3" Drug 6709_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.97E-04 1.00E+00 1.40E-02 1.54E-01 18 187 "ABAT,SORBS1,FYN,RGL1,ACSBG1,GLS,VAMP1,GRIK2,TGFBR3,USP2,PCDH9,SERPINE2,DNAJC12,DNAJC6,JAKMIP2,PLPPR4,VWA5A,RASGRP2" Drug 1047_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.97E-04 1.00E+00 1.40E-02 1.54E-01 18 187 "MAPT,ADD3,CDC42BPA,PPM1E,SYBU,CCDC88A,GPR153,CSPG5,CAPRIN2,FYN,ZCCHC24,PIK3CD,NMT2,DNAJC12,KIAA0513,PTCH1,SUSD4,EFNA3" Drug 3677_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.97E-04 1.00E+00 1.40E-02 1.54E-01 18 187 "SLC8A2,SLCO1A2,TAGLN3,MYBPC1,INKA2,ADGRL3,GPM6A,GRIK2,NEURL1,PDE4B,POU3F4,FEZ1,CTNND2,EDRF1,PTHLH,SRGAP3,ARNT2,PID1" Drug CID000000295 "guanosine 3',5'-cyclic monophosphoric acid" Stitch 5.01E-04 1.00E+00 1.41E-02 1.55E-01 40 577 "ACHE,MRVI1,ADCY2,RYR1,ADORA1,ADORA3,AGT,ACTL6B,SCMH1,PDE8B,ATP1A2,ATP1A3,SEPT3,MLC1,CACNA1A,CACNA1E,NPPA,CACNB2,GUCY1A2,GUCY1A1,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,NTSR2,CHGA,CHRM1,PHKG1,SLC22A6,PTPA,PRKACB,PRKCG,PRKCZ,KCNMA1,DNAH9,SLC25A18,PHC2,CACNG7,RPE65" Drug CID003025961 MPEP Stitch 5.02E-04 1.00E+00 1.41E-02 1.55E-01 9 59 "GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,TPM3,EEF1A2" Drug CID000005275 SR 95531 Stitch 5.02E-04 1.00E+00 1.41E-02 1.55E-01 9 59 "ABAT,GAD2,GRIA1,GRIA2,GRIA4,GRIK4,GRM3,KCNN3,EEF1A2" Drug CID000016953 thioflavin T Stitch 5.04E-04 1.00E+00 1.42E-02 1.55E-01 15 141 "SERPINA3,ACHE,WLS,FOXG1,APC,NLGN1,SNCB,GFAP,CCKBR,PAH,PACSIN1,MAPK10,PRTFDC1,ATN1,EN2" Drug CID000005722 zaprinast Stitch 5.04E-04 1.00E+00 1.42E-02 1.55E-01 15 141 "RYR1,ADD3,ADORA1,ADORA3,AGT,PDE8B,NPPA,GUCY1A2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PRKACB,KCNA6" Drug CID000065863 sertaconazole Stitch 5.23E-04 1.00E+00 1.47E-02 1.61E-01 20 220 "SERPINA3,RPL38,MAPT,MBP,MOBP,APBA2,ASTN1,SNAP25,NRG3,GAD2,RHBDL3,PCDHGA3,GRID1,PDE4B,FADS2,ETNPPL,PRDM2,BLOC1S6,KCNN3,RTN4" Drug 3177_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.30E-04 1.00E+00 1.48E-02 1.63E-01 18 188 "DPF1,ADD3,PPM1E,SORBS1,SYBU,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,BTRC,TGFBR3,PIK3CD,DNAJC12,CABP1,KIAA0513,KCNC1,TTLL7" Drug 4845_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-04 1.00E+00 1.48E-02 1.63E-01 18 188 "MBP,ARID1A,TESK2,PKP4,MADD,ALDH4A1,PALLD,ADAM15,GOLGB1,ARHGAP19,UBTF,CCSER2,PMS2,NSD2,CTNND1,PRDM2,PLEKHB2,RGS10" Drug 2571_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-04 1.00E+00 1.48E-02 1.63E-01 18 188 "ADORA3,FGR,GPR153,NDUFA5,RND1,ACSBG1,MYRF,PTBP2,USP2,RBFOX2,ZMYND8,ZFYVE9,DZIP3,EDRF1,ZBTB16,PHC2,EFNA3,LPAR6" Drug CID000446903 norbiotin Stitch 5.39E-04 1.00E+00 1.51E-02 1.65E-01 10 72 "ADORA1,GAD2,GFAP,NODAL,GRIA1,GRIA4,GRM3,HRH3,SLC17A6,EEF1A2" Drug CID000130818 MNQX Stitch 5.46E-04 1.00E+00 1.53E-02 1.67E-01 5 18 "B3GAT1,GRIA1,GRIA2,GRIA4,GRM3" Drug CID000448615 AC1L9M5J Stitch 5.54E-04 1.00E+00 1.54E-02 1.69E-01 20 221 "MAPT,ADAR,RXRG,FGF1,SLC1A2,GFAP,SEPT3,CACNA1E,GRIA1,GRIA2,GRIK2,GRIK3,GRIK4,NTSR2,SDC3,PUM1,LRP8,NTM,VANGL2,ELAVL3" Drug CID000002460 "dibutyryl cyclic 3',5'-AMP" Stitch 5.55E-04 1.00E+00 1.54E-02 1.69E-01 39 561 "MAG,MBP,ADCY2,ADORA1,ADORA3,FCGR1A,AGT,FGF1,ACTL6B,SLC1A2,ATP1A2,ATP1A3,GPR162,GFAP,NFIA,GNAS,NPPA,LEFTY2,TGFBR3,USP2,PDE1C,PDE2A,PDE3B,PDE4B,TMPRSS5,CHGA,CHRM1,FTO,SPATA6,PTPA,PRKACB,PRKCG,MAPK8,MAPK10,PTAFR,PTHLH,PYGM,CALN1,RAP1GAP" Drug CID000002337 benzocaine Stitch 5.55E-04 1.00E+00 1.54E-02 1.69E-01 7 37 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug CID004631218 AC1NDT8A Stitch 5.55E-04 1.00E+00 1.54E-02 1.69E-01 7 37 "ASIC1,SLC8A2,SLC8A3,SHANK2,TNS1,SRGAP3,RALGDS" Drug CID000060803 sipatrigine Stitch 5.55E-04 1.00E+00 1.54E-02 1.69E-01 7 37 "SCN4B,SLC1A2,SCN3B,CACNA1E,ASIC3,KCNK2,SLC17A6" Drug CID003035793 AH 21-132 Stitch 5.55E-04 1.00E+00 1.54E-02 1.69E-01 7 37 "ADORA1,PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000002360 ODAP Stitch 5.56E-04 1.00E+00 1.54E-02 1.69E-01 8 48 "FOLH1,NDUFA5,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug ctd:C016599 mono-(2-ethylhexyl)phthalate CTD 5.56E-04 1.00E+00 1.54E-02 1.69E-01 44 657 "MAPT,MBP,LGR4,F3,ADARB2,RXRG,GALNT13,RYR1,ADORA1,DISP3,ANK1,DOCK10,JAKMIP3,RPH3A,SCG3,SLIT1,ATP1A3,B3GALT2,KIF21B,CLASP2,RND1,POPDC3,TJP1,AIFM1,TLL2,PAH,LGI1,CADM1,ST8SIA5,CABP1,MED1,RGS6,ATRNL1,CHD5,NCAN,ZBTB16,PTCH1,PTPRD,SLC25A48,DPP6,USH1C,RGS7,SLC4A10,EPB41L1" Drug 7285_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.57E-04 1.00E+00 1.54E-02 1.69E-01 17 173 "MAPT,F3,TESK2,FYN,TNIK,RGL1,GLS,PCDH9,PIK3CD,DNAJC12,KIAA0513,SYTL2,DNAJC6,JAKMIP2,PLPPR4,EFNA3,EPB41L2" Drug 981_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.57E-04 1.00E+00 1.54E-02 1.69E-01 17 173 "ADD3,TUBB4A,PPM1E,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,BTRC,PADI2,PCDH9,ACOT7,PIK3CD,DNAJC12,KIAA0513,DNAJC6" Drug CID000105060 indo-1 Stitch 5.58E-04 1.00E+00 1.55E-02 1.69E-01 12 99 "MAG,ADGRV1,RYR1,AGT,DGKZ,SLC8A3,SNAP25,ATP2B2,CACNB2,CHRM1,PRKCG,KCNMA1" Drug CID000005578 trimethoprim Stitch 5.58E-04 1.00E+00 1.55E-02 1.69E-01 12 99 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,FOXG1,MSRA,SCN3B,GRIA1,PAH,ASIC3,HNRNPK" Drug CID000005279 NSC618487 Stitch 5.60E-04 1.00E+00 1.55E-02 1.70E-01 58 935 "MAPT,MBP,AGT,FGF1,PLA2G6,ACTL6B,FGR,SELL,ANK1,DGKZ,DGKD,USP16,MADD,SNAP25,SNCB,FYN,ATP2B2,TNIK,ADHFE1,NODAL,NPPA,CACNB2,CAMK2A,CAMK2G,NUMA1,GRM3,LEFTY2,TJP1,AIFM1,ZFP91,TNFRSF1B,CHRM1,PHKG1,CAMKV,PIK3CD,PTPA,SNCAIP,FEZ1,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,KLK6,PLPPR5,PTHLH,KCNA1,KCNA2,KCNA4,KCNA6,KCNJ4,RAB5B,ABI1,PAK5,CAMK1G,SEC61A2,BAALC" Drug CID000121918 "L-689,560" Stitch 5.61E-04 1.00E+00 1.55E-02 1.70E-01 6 27 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000000595 dl-cystine Stitch 5.79E-04 1.00E+00 1.60E-02 1.75E-01 14 128 "AGT,SLC1A2,RPH3A,SLC1A7,FYN,KIRREL3,NKX2-2,GRIK4,TMEM25,TJP1,MAGI1,RGS6,PTPRO,RGS7" Drug CID000016052 Ho-14 Stitch 5.90E-04 1.00E+00 1.62E-02 1.78E-01 3 5 "SOX10,NUMA1,NTM" Drug ctd:C472365 "3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine" CTD 5.90E-04 1.00E+00 1.62E-02 1.78E-01 3 5 "GRIA2,PTPN5,PDYN" Drug CID000167842 bromowillardiine Stitch 5.90E-04 1.00E+00 1.62E-02 1.78E-01 3 5 "SOX10,GRIK3,GRIK4" Drug ctd:C004961 beta-hydroxyisovaleric acid CTD 5.90E-04 1.00E+00 1.62E-02 1.78E-01 3 5 "USP28,USP16,USP2" Drug CID000008408 N2-M Stitch 5.90E-04 1.00E+00 1.62E-02 1.78E-01 3 5 "FGF1,TNIK,GPM6A" Drug 3629_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.01E-04 1.00E+00 1.65E-02 1.80E-01 18 190 "NDRG2,KLRC4,RYR1,SHANK2,CSPG5,SLCO1A2,SOX10,FGF17,RND1,WSCD1,USP2,PTGDR2,TUB,TENM4,KCND3,SRGAP3,RAD52,TTLL7" Drug 4663_UP Clioquinol [130-26-7]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.01E-04 1.00E+00 1.65E-02 1.80E-01 18 190 "BRINP2,KIF21B,SOX10,ALDH1L1,RND1,SLCO1C1,ADAMTS8,SPX,PTGDR2,GPR37L1,SPATA6,PROX1,PRDM2,KCNC1,PARP11,SUSD4,ATN1,DSCAM" Drug 4322_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.01E-04 1.00E+00 1.65E-02 1.80E-01 18 190 "C1orf61,ANK3,PKP4,SLC1A7,PDE8B,ASPH,GNG3,NUMA1,SF1,CRMP1,PRKAB2,PRDM2,SMG7,RAD52,ATN1,RGS10,VWA5A,EPB41L1" Drug 6979_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.01E-04 1.00E+00 1.65E-02 1.80E-01 18 190 "PAQR6,GAS7,BCAN,NLGN1,BCAS1,NAP1L2,NCAM1,SEMA4A,WSCD1,CCKBR,PDE3B,CTNND2,KLK6,KCNK2,ST8SIA3,SSPN,LRRC23,RASGRP2" Drug 7145_DN Nocodazole [31430-18-9]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.01E-04 1.00E+00 1.65E-02 1.80E-01 18 190 "TACC2,TAGLN3,TNIK,BCL2L2,RGL1,GNAS,TCF7L2,REPS2,PCDH9,KIAA1549L,CCSER2,PPP2R5C,TENM4,KIAA0513,SYTL2,DLG3,PID1,ATG16L1" Drug 3873_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.35E-04 1.00E+00 1.73E-02 1.90E-01 17 175 "ADD3,TUBB4A,FYN,TNIK,ZCCHC24,NMNAT2,ADGRB2,RGL1,ACSBG1,TGFBR3,PIK3CD,DNAJC12,RIMS3,TTLL7,EFNA3,VWA5A,RASGRP2" Drug 909_UP HC toxin from Helminthosporium carbonum; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.35E-04 1.00E+00 1.73E-02 1.90E-01 17 175 "ADD3,TUBB4A,FHL1,PPM1E,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 2777_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.35E-04 1.00E+00 1.73E-02 1.90E-01 17 175 "ADD3,PPM1E,CCDC88A,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug 3428_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.35E-04 1.00E+00 1.73E-02 1.90E-01 17 175 "ADD3,PPM1E,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug CID000002284 baclofen Stitch 6.40E-04 1.00E+00 1.74E-02 1.91E-01 18 191 "ABAT,ADCY2,RYR1,ADORA1,ADORA3,ATP1A3,GABBR1,GAD2,CACNA1A,CACNA1E,NPPA,CACNB2,GRM3,DPYSL5,KCNJ4,KCNJ9,KCNJ10,CACNG7" Drug 4614_UP Colchicine [64-86-8]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 1.74E-02 1.91E-01 18 191 "EMID1,ACTN2,SORBS1,NLGN1,ASCL1,SLCO1A2,B3GAT1,RAP1GAP2,PHLDB1,GNG4,CACNB2,DAAM2,PDE1C,CHD5,KCNH1,ABCC9,SIDT2,RASGRP2" Drug 5957_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 1.74E-02 1.91E-01 18 191 "FOXG1,RPH3A,DNAH17,BRINP2,EMC1,GART,PHLDB1,RND1,NEURL1,CDC42,KCNJ4,TMCC2,PEX5,NUP214,RET,EFNA3,VWA5A,EN2" Drug CID005289556 V ms Stitch 6.41E-04 1.00E+00 1.74E-02 1.91E-01 8 49 "GAD2,GPM6B,TGFBR3,ANLN,KCNA4,KCND3,SLC17A6,RBM12" Drug CID000441452 methylenecyclopropylglycine Stitch 6.41E-04 1.00E+00 1.74E-02 1.91E-01 8 49 "ADORA1,SLC1A7,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug ctd:C031180 chrysene CTD 6.48E-04 1.00E+00 1.76E-02 1.93E-01 55 880 "RTN3,MEG3,MDM4,RYR1,ADD3,ERMN,SELL,ANK3,MAGI3,TACC2,SORBS1,ZNF365,RUFY2,MSR1,ASPH,DDX25,EIF4G3,SCN3B,MYBPC1,CPLX2,INKA2,GJB1,SEPT3,PSRC1,TCF7L2,PTPN5,USP2,MFSD2A,P2RX7,ZDHHC22,PAH,ATG4C,CDC42,ZMYND8,HMGB1,CA14,LRTM2,PFKFB3,TMEFF2,CPT1C,CELF5,TENM4,PLCH2,FGFR1OP2,PHYHIP,MED24,PTPRZ1,DNM2,FAM57B,FAM13C,TTLL7,SYT15,SSPN,BSCL2,EPB41" Drug ctd:D003976 Diazinon CTD 6.50E-04 1.00E+00 1.76E-02 1.93E-01 86 1525 "ACHE,ACLY,SYNDIG1,ARID1A,MDM4,NDRG2,F3,ADCY2,HHATL,CDC7,TUBB4A,FGF1,PLA2G6,FGF14,FOXM1,APBB1,ZCCHC17,JAKMIP3,USP16,SLC1A2,MADD,SLC6A9,ARHGAP5,CGREF1,BRINP2,SMARCE1,ATM,SNCB,FYN,DKK3,SON,WDTC1,CPLX2,GFAP,RCOR2,FGF17,NKX2-2,VWC2,DDR1,GPR17,CAMK2G,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,AIFM1,PAX6,CDH8,LGI1,LILRA4,PDE1A,PDE1C,CHGA,CHRM1,TUB,CHRM4,CHRNB2,NRXN2,FAAP20,PHACTR3,PRKAB2,PRKCZ,PSD,SYNC,PTCH1,KCNA1,KCNA2,SMG7,PARD6A,TMCC2,KCNK1,RAB3IL1,PID1,DNM2,RAP1GAP,RTN4,RET,RGS10,ARHGEF10L,SFXN5,SH3GLB1,VWA5A" Drug CID000006616 camphene Stitch 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "EYA1,MASP1,TOX,KCNH1" Drug CID000148200 YM872 Stitch 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "GRIA1,GRIA2,GRIA4,GRM3" Drug ctd:D010197 Pancuronium CTD 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "ACHE,CHRM1,CHRM4,CHRNB2" Drug CID005313815 AC1NSPXR Stitch 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "PLA2G6,ANK1,ANK2,ANK3" Drug CID000069892 0-ol Stitch 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000120282 phenazine-1-carboxamide Stitch 6.54E-04 1.00E+00 1.76E-02 1.93E-01 4 11 "SEMA6A,PTPN5,HPR,PNKD" Drug CID000656725 reactive blue 2 Stitch 6.55E-04 1.00E+00 1.76E-02 1.93E-01 11 87 "ADAR,ADARB2,ADORA1,ADORA3,APC,MIER1,GFAP,CACNA1E,P2RX7,P2RY12,SV2A" Drug CID000004826 pinacidil Stitch 6.55E-04 1.00E+00 1.76E-02 1.93E-01 11 87 "ADORA1,ADORA3,ABCC8,NPPA,GUCY1A2,PRKCG,KCNA2,KCNJ4,KCNJ9,KCNJ10,ABCC9" Drug CID000002935 GAMs Stitch 6.58E-04 1.00E+00 1.77E-02 1.94E-01 7 38 "NUCB1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug CID000005115 4CPG Stitch 6.58E-04 1.00E+00 1.77E-02 1.94E-01 7 38 "SLC1A2,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000002531 calmidazolium chloride Stitch 6.61E-04 1.00E+00 1.78E-02 1.95E-01 16 160 "ADCY2,AGT,PLA2G6,SLCO1A2,ATP2B2,CACNA1A,CACNA1E,P2RX7,PDE1C,CAMKV,PRKACB,PRKCG,KCNN3,DNAH9,CAMK1G,NUP214" Drug CID000443040 imide Stitch 6.72E-04 1.00E+00 1.80E-02 1.98E-01 10 74 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,GLS,ASIC3,PTCH1,CA10" Drug CID000001263 AC1L1B35 Stitch 6.72E-04 1.00E+00 1.80E-02 1.98E-01 10 74 "MAPT,ACHE,MTR,WWC1,TNFRSF1B,TPM3,TPM4,KLK6,SIRPA,RET" Drug CID000036095 dibutyryl cyclic GMP Stitch 6.77E-04 1.00E+00 1.81E-02 1.98E-01 14 130 "AGT,MYBPC1,MLC1,NPPA,CCKBR,GUCY1A2,PDE1C,PDE2A,PDE4B,CHRM1,PTPA,PRKACB,PRKCG,KLK6" Drug 6546_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.77E-04 1.00E+00 1.81E-02 1.98E-01 17 176 "F3,TUBB4A,HPCAL4,SORBS1,ATM,FYN,TNIK,ADGRB2,RGL1,GLS,USP2,PCDH9,CCSER2,DNAJC12,DNAJC6,PLPPR4,EPB41L2" Drug 6820_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.77E-04 1.00E+00 1.81E-02 1.98E-01 17 176 "ADD3,SORBS1,SYBU,CCDC88A,FYN,ZCCHC24,RGL1,RND1,ACSBG1,SERPINE2,PIK3CD,DNAJC12,RIMS3,PTCH1,DNAJC6,EFNA3,RASGRP2" Drug 423_UP staurosporine; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 6.77E-04 1.00E+00 1.81E-02 1.98E-01 17 176 "PAQR6,TACC2,ALDH4A1,PALLD,GJB1,VAMP1,ZNF638,CAMSAP2,OMG,TPM4,CRMP1,MAPK8,ITIH2,NAV2,RAP1GAP,DSCAM,SIDT2" Drug 7047_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.77E-04 1.00E+00 1.81E-02 1.98E-01 17 176 "DPF1,ABAT,TESK2,SH3GL2,SORBS1,RGL1,GLS,CDK5R2,TGFBR3,PCDH9,PIK3CD,DNAJC12,DNAJC6,PLPPR4,SIDT2,EFNA3,EPB41L2" Drug CID000000190 adenine Stitch 6.78E-04 1.00E+00 1.81E-02 1.98E-01 36 510 "ADAR,ADARB2,ADCY2,RYR1,ADORA1,ADORA3,APC,MSRA,DDX25,AHCYL1,NMNAT2,GART,ADHFE1,NFIA,ABCC8,GLS,GPM6A,CACNA1E,RFFL,CYB561A3,P2RX7,AIFM1,PAH,HPS5,RBFOX2,TPM3,PDE2A,PMP2,PMS2,P2RY12,NOS1AP,PRTFDC1,AK5,PYGM,SLC25A41,LPAR6" Drug 6207_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.80E-04 1.00E+00 1.81E-02 1.98E-01 18 192 "MAPT,ARID1A,FOXRED2,CDC42BPA,PPFIA1,EMC1,FAM168A,TCF7L2,GPR19,PSD3,UBTF,NSD2,CHD1L,FEZ1,RBPJ,BRINP3,KIF2A,EPB41L2" Drug 1240_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.80E-04 1.00E+00 1.81E-02 1.98E-01 18 192 "ASIC1,ITSN1,APC,SLC6A9,FYN,TNIK,RGL1,KAZN,GNG3,CHRNB2,DNAJC12,PTAFR,DNAJC6,PLPPR4,RABGAP1L,RAB3IL1,ROM1,PLEKHO1" Drug 1153_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.80E-04 1.00E+00 1.81E-02 1.98E-01 18 192 "EPS8,PAQR6,WLS,ADD3,ITSN1,PDE8B,ZCCHC24,RGL1,CAMSAP2,NRGN,GRIN1,INA,PADI2,RBFOX2,TPM3,SERPINE2,DNAJC6,EFNA3" Drug 1209_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.80E-04 1.00E+00 1.81E-02 1.98E-01 18 192 "MAPT,RASA3,ITSN1,SYBU,ZNF365,FYN,TNIK,PHLDB1,OPCML,TGFBR3,NMT2,DNAJC12,MICAL1,PTAFR,PTCH1,DNAJC6,PLPPR4,TMCC2" Drug 7485_UP Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.80E-04 1.00E+00 1.81E-02 1.98E-01 18 192 "MAPT,SLC1A7,SLC6A9,ALDH4A1,GLS,SEMA4A,GNG3,USP2,FADS2,MICAL1,MICAL2,SDC3,PTAFR,JAKMIP2,ITIH2,TMCC2,RAB3IL1,DSCAM" Drug CID000060839 aptiganel Stitch 6.90E-04 1.00E+00 1.83E-02 2.01E-01 6 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000001228 C-PP Stitch 6.90E-04 1.00E+00 1.83E-02 2.01E-01 6 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug 3462_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.22E-04 1.00E+00 1.91E-02 2.10E-01 17 177 "ADD3,PPM1E,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,SERPINE2,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug CID000023991 xenon Stitch 7.22E-04 1.00E+00 1.91E-02 2.10E-01 11 88 "MBP,ATP2B2,JPH4,CACNA1A,GRIA1,GRIA2,GRIA4,GRM3,PMP2,ITIH2,ATN1" Drug 3807_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.23E-04 1.00E+00 1.91E-02 2.10E-01 18 193 "FGR,BCAS1,PKNOX2,ASCL1,CCDC181,CADM3,CPLX2,RND1,AJAP1,VAMP1,NEURL1,SEZ6L,CADM1,SULT4A1,POU3F2,MAGI2,SMG7,DTNA" Drug 2482_UP Tolazamide [1156-19-0]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.23E-04 1.00E+00 1.91E-02 2.10E-01 18 193 "ABAT,ADORA3,MOBP,ANK3,TAGLN3,SLN,NEUROD1,TCF7L2,CDC42,CDH10,PDE2A,CABP1,DNAJC6,ITIH2,STMN4,KCNN3,TTLL7,ELAVL3" Drug CID000001323 DiC8 Stitch 7.27E-04 1.00E+00 1.92E-02 2.11E-01 15 146 "PLA2G6,DGKZ,DGKD,NRGN,TJP1,PDYN,TJP2,P2RY12,PRKACB,PRKCG,PKN2,PRKCZ,PTHLH,KCNA6,KCNQ2" Drug CID000059708 etiracetam Stitch 7.29E-04 1.00E+00 1.92E-02 2.11E-01 9 62 "ABAT,AMPH,GAD2,GFAP,GRIA1,GRIA2,GRIA4,GRM3,SV2A" Drug CID000001922 8-phenyltheophylline Stitch 7.29E-04 1.00E+00 1.92E-02 2.11E-01 9 62 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3,APC,GPR162,P2RX7,P2RY12" Drug CID000004799 AC1L1IZE Stitch 7.31E-04 1.00E+00 1.93E-02 2.11E-01 14 131 "ADAR,ADARB2,RYR1,ADORA1,ADORA3,TUBB4A,APC,GPAM,DNAH17,ATP2B2,P2RX7,P2RY12,MAPK10,DNAH9" Drug CID000107688 obidoxime Stitch 7.37E-04 1.00E+00 1.94E-02 2.13E-01 8 50 "SERPINA3,ACHE,MBP,B3GAT1,GFAP,CHGA,CHRM1,TOX" Drug CID000000231 LS-63783 Stitch 7.47E-04 1.00E+00 1.97E-02 2.16E-01 51 805 "MBP,F3,ADCY2,FABP7,AGT,SCNN1D,PLA2G6,SEMA6A,ANXA7,DGKZ,GPAM,DGKD,SLC1A6,MADD,BCO1,ATP1A2,ATP1A3,FYN,NODAL,LEFTY2,GUCY1A2,KCNK10,PCDH8,PTGDR2,NTSR2,HMGB1,HPSE2,CHRM1,CHRNB2,PIK3CD,FADS2,COL9A2,P2RY12,ATCAY,VCAN,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PLPPR5,PTAFR,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCNH1,KCNK1,KCNK2,KCNMA1" Drug 2764_UP Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "MAPT,NDRG2,RYR1,ANK1,RASA3,PKNOX2,SLC6A9,ASPH,ATP2B2,ZCCHC24,GAD2,SLCO1C1,HAP1,NEURL1,MICAL1,RIMS3,PRDM2,PARD6A" Drug 3880_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "MAPT,ARID1A,NDRG2,ADCY2,ADORA1,ASCL1,ASPH,ATM,ATF7,CDC42,PCDH9,ZFYVE9,NMT2,CNTN1,POU3F4,PTAFR,TMCC2,VWA5A" Drug 6893_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ASIC1,TMEM156,FHL1,ANK3,APBB1,DLL3,ADGRB2,COLGALT2,VAMP1,WSCD1,GPR17,NEURL1,PIK3CD,CCSER2,MED1,TOX,BEND5,LPAR6" Drug 4575_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "MDM4,ADCY2,FOXRED2,FGF1,PLA2G6,SLC1A7,PKNOX2,SLC6A9,TAGLN3,GAD2,ACSBG1,BTRC,REPS2,SPATA6,RABGAP1L,DTNA,PAK5,RGS10" Drug 6160_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ADORA3,FOXRED2,SLC2A5,GLS,KAZN,PSD3,OMG,RBFOX2,CADM1,CCSER2,CRMP1,PTPA,MICAL2,MAPK8,ITIH2,RAD52,RGS10,VWA5A" Drug 3370_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "CEND1,TUBB4A,FOXG1,MSR1,NFASC,ABCC8,VAMP1,WSCD1,NUMA1,PTAFR,ITIH2,KCND3,RABGAP1L,RAD52,DPP6,NUP214,EN2,RASGRP2" Drug 3539_DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ARID1A,PLA2G6,FHL1,CDC42BPA,APC,ATM,EMC1,PHLDB1,ROBO3,GNG4,TCF7L2,NEURL1,ZMYND8,RIMS3,RALGDS,EFNA3,ROM1,EN2" Drug 4083_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "KCNIP2,PLA2G6,ASIC4,ANK1,APBB1,NTNG1,AQP4,SLCO1A2,CADM3,SOX10,GNG3,GNG4,SPX,CNTN1,MICAL2,KCND3,RGR,RASGRP2" Drug 3345_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "MAPT,WLS,CDC42BPA,DNAH17,DLL3,SLN,ATM,NEUROD1,CACNB2,PDE3B,CHRNB2,CRMP1,CNIH3,PRDM2,KCND3,TMCC2,RAD52,ST8SIA3" Drug 4269_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "KIAA1109,SELL,APC,TAGLN3,WDTC1,KIF21B,NPAS3,GNG4,KLHL4,OMG,PTGDR2,LILRA4,PDE4B,CAMKV,RGS6,VCAN,ATN1,RASGRP2" Drug 3043_UP Niacin [59-67-6]; Up 200; 32.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ACHE,MBP,ANK1,SLCO1A2,ALDH4A1,RND1,ACSBG1,GRIK2,PAH,HPSE2,SULT4A1,PRKCZ,MAPK10,ZBTB16,KCND3,DSCAM,CRTAC1,CAMK1G" Drug 4441_UP chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "CEND1,FOXRED2,FGF1,FOXG1,NTNG1,ATM,SOX10,ALDH1L1,MYRF,GUCY1A2,HRH3,TMPRSS5,ZFYVE9,CTNND2,RIMS3,SMG7,SRGAP3,ATN1" Drug 4125_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "MAPT,NDRG2,MOBP,ANK1,GAS7,GFAP,VAMP1,OMG,OPCML,FLRT1,SULT4A1,SNCAIP,MICAL2,KCNMA1,RAB3IL1,RGS10,SSPN,OLIG2" Drug 5752_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "HPCAL4,APBB1,NLGN1,RND1,CDK5R2,GPM6A,GRIA4,OMG,HRH3,PLEKHB1,KIAA1549L,CRMP1,MAPK10,PHYHIP,KCNJ4,NAV2,DSCAM,DTNA" Drug 3173_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ASIC1,FHL1,MSR1,DDX25,ALDH1L1,MLC1,GLS,BTRC,GPM6B,NPPA,PSD3,NEURL1,NMT2,CRMP1,MICAL2,NOS1AP,PRDM2,KCND3" Drug 4159_DN "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.68E-04 1.00E+00 1.99E-02 2.19E-01 18 194 "ACTN2,NDRG2,APBA2,ALDH4A1,GNG3,NUMA1,PDE3B,ZMYND8,SNCAIP,MAPK10,SYNC,PTHLH,ITIH2,PRDM2,PARD6A,PLEKHB2,ATG16L1,DTNA" Drug CID004636050 AC1NE3N8 Stitch 7.69E-04 1.00E+00 1.99E-02 2.19E-01 17 178 "SCN4B,SCNN1D,SLC14A1,MTR,ATP1A2,ATP1A3,SCN3B,GLS,CACNA1A,INA,ASIC3,CHRM1,P2RY12,MAPK10,KCNJ9,ATN1,EPB41" Drug 4483_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.69E-04 1.00E+00 1.99E-02 2.19E-01 17 178 "DPF1,ABAT,MAPT,TUBB4A,SORBS1,FYN,RGL1,NRGN,USP2,TNS1,PCDH9,CADM1,PIK3CD,DNAJC12,KIAA0513,KCND3,TTLL7" Drug 5065_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.69E-04 1.00E+00 1.99E-02 2.19E-01 17 178 "MAPT,TESK2,FYN,TNIK,RGL1,RND1,GLS,USP2,PCDH9,DNAJC12,KIAA0513,PTCH1,DNAJC6,PLPPR4,SRGAP3,PID1,SIDT2" Drug CID000000274 "adenosine 3',5'-cyclic phosphate" Stitch 7.74E-04 1.00E+00 2.00E-02 2.20E-01 56 907 "MBP,SYT9,ADAR,ADARB2,ADCY2,ADCYAP1R1,ADORA1,ADORA3,FCGR1A,AGT,FGF1,ACTL6B,PDE8B,NCAM1,SYT4,GNAS,NODAL,ATF7,NPPA,AZIN2,CAMK2G,SYT6,GRM3,CCKBR,PTPN5,LEFTY2,GUCY1A2,HRH3,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CA14,CHGA,PFKFB3,CHRM1,PHKG1,CAMKV,CPT1C,FTO,COL9A2,P2RY12,PTPA,PRKACB,SDC3,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PTHLH,KCNMA1,KCNQ2,PYGM,CAMK1G" Drug CID005195770 Ni-Fe active center Stitch 7.74E-04 1.00E+00 2.00E-02 2.20E-01 7 39 "MTR,SOX10,DNER,GNAS,CHRM1,NEGR1,KCNK1" Drug CID004473765 AC1NBU2S Stitch 7.75E-04 1.00E+00 2.00E-02 2.20E-01 13 117 "RTKN,RYR1,AGT,CACNA1A,CACNA1E,NPPA,CACNB2,HAP1,GUCY1A2,GUCY1A1,AIFM1,PYGM,CACNG7" Drug CID000164073 Pkcs Stitch 8.00E-04 1.00E+00 2.07E-02 2.27E-01 19 211 "MBP,TUBB4A,FGF1,DGKZ,DGKD,RPH3A,ARFGAP1,NEUROD1,NRGN,CDC42,CHRM1,PIK3CD,P2RY12,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PARD6A" Drug CID003036508 Pc 12 Stitch 8.00E-04 1.00E+00 2.07E-02 2.27E-01 19 211 "ADORA1,ADORA3,FGF1,SLC8A2,ASCL1,SNAP25,CNTN2,GRIA2,AIFM1,CHGA,CHRNB2,PIK3CD,CPT1C,NCAN,PRKACB,PRKCG,MAPK8,MAPK10,RAP1GAP" Drug 4558_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "PLA2G6,GAS7,SLC1A6,CCDC181,SOX10,ALDH1L1,VAMP1,NEURL1,ASIC3,HPCA,CTNND2,PRDM2,SRGAP3,RAB3IL1,RASGRF1,FAM13C,DTNA,SLC6A15" Drug 4373_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "BCAN,BCO1,PDE8B,RND1,GLS,GNG4,WSCD1,PSD3,DAAM2,CDC42,SERPINE2,VAV2,POU3F2,PTAFR,ATG16L1,NUP214,EFNA3,RASGRP2" Drug 6006_UP Nifedipine [21829-25-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "SYNDIG1,LRRTM4,SLC6A9,CADM3,GAD2,ALDH1L1,GLS,NEURL1,PDE1C,PDE4B,MICAL1,OSBPL3,MASP1,ITIH2,PRDM2,DSCAM,USH1C,RASGRP2" Drug 6131_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ACTN2,CDC42BPA,ITSN1,RAP1GAP2,GLS,PSD3,OMG,USP2,INA,PDE4B,SERPINE2,CCSER2,CRMP1,PRKCZ,EDRF1,PEX5,SIDT2,VWA5A" Drug 5873_UP Nadide [53-84-9]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MAPT,PKP4,APC,CGREF1,ASTN1,SEMA4A,GPR19,COL9A2,MICAL2,MAPK10,KLK6,PTHLH,RABGAP1L,DLG3,DSCAM,DTNA,VWA5A,LPAR6" Drug 2260_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "CDC42BPA,SLCO1A2,ASPH,SNAP25,ADAM15,ADGRB2,PSD3,CDC42,TNS1,FADS2,CHD5,PTAFR,PRDM2,MAGI2,KCND3,NTM,ATN1,RASGRP2" Drug 5119_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ACHE,FGF1,SORBS1,PKNOX2,DNAH17,ASTN1,ATP1A2,ATP1A3,B3GALT2,CADM3,NEUROD1,KLHL4,SEZ6L,VAV2,CRMP1,VCAN,DTNA,ST8SIA3" Drug 2245_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ACTN2,NDRG2,FOXRED2,FHL1,CDC42BPA,ASPH,ZCCHC24,EMC1,CACNA1A,WSCD1,OPCML,CDH10,CHRNB2,COL9A2,PEX5,NUP214,EFNA3,VWA5A" Drug 6266_DN Butamben [94-25-7]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ARID1A,FHL1,ALDH4A1,WDTC1,BTRC,NRGN,VAV2,CHD1L,IGSF1,GON4L,SMG7,PEX5,RAB3IL1,DNM2,RALGDS,DSCAM,DTNA,ZNF248" Drug 6101_DN Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MAPT,KIAA1109,FHL1,GAS7,ZCCHC24,CADM3,EMC1,PHLDB1,GNAS,NUMA1,PSD3,TGFBR3,ZFYVE9,CNTN1,SF1,SDC3,RALGDS,DTNA" Drug 3828_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "NDRG2,ADCY2,C1orf61,APBA2,NPAS3,POPDC3,ATF7,NUMA1,OLR1,ZFYVE9,SULT4A1,VAV2,CNTN1,SNCAIP,PTAFR,TMCC2,PID1,RASGRP2" Drug 3201_DN Lidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "APC2,EMID1,WLS,FOXRED2,SEMA6A,CDC42BPA,ALDH4A1,WDTC1,EMC1,ACSBG1,KAZN,USP2,CDH10,PLEKHB1,CAMKV,ARHGEF4,EDRF1,PTPRO" Drug 6692_UP Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "SCNN1D,APBB1,SLC6A9,SNAP25,ATP1A3,SOX10,MYH7,INKA2,SLCO1C1,VAMP1,CNTN2,RGS6,MICAL2,MAPK8,KCNC1,ATN1,DTNA,EPB41" Drug 5582_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "DPF1,TTYH1,EMID1,NDRG2,MSR1,ASCL1,BRINP2,CADM3,ROBO3,OMG,PCDH9,PHKG1,SULT4A1,IFFO1,ARHGEF4,KCND3,BEND5,ELAVL3" Drug 4156_DN Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MDM4,ADORA1,CDC42BPA,APC,DNAH17,SNAP25,RND1,ROBO3,HAP1,NEURL1,PDE1C,PLEKHB1,CRMP1,SNCAIP,PRDM2,ATN1,RGS10,VWA5A" Drug 6224_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ACHE,ADORA3,FHL1,SYBU,CAPRIN2,SEMA4A,CACNB2,MAGI1,ZMYND8,PHKG1,SERPINE2,ZFYVE9,EDRF1,PRDM2,RALGDS,ATN1,NUP214,SSPN" Drug 6662_UP Fluspirilen [1841-19-6]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "ACTN2,ASIC4,SEMA6C,SORBS1,PDE8B,ATM,ATP2B2,NCAM1,HAP1,GRM3,PCSK2,SULT4A1,EDRF1,PTAFR,MAGI2,KCND3,NTM,PLEKHO1" Drug 3969_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "SYNDIG1,ACTN2,ARID1A,CLIP1,KIAA1109,SLC2A5,PKNOX2,SHANK2,SOX10,ALDH1L1,SEMA4A,GRIA4,GRIN1,SEZ6L,GPR37L1,POU3F4,CRMP1,NOS1AP" Drug 4508_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MDM4,KIAA1109,APC,PDE8B,ASPH,ALDH4A1,WDTC1,BTRC,PSD3,ZFYVE9,MAPK8,GON4L,PLPPR1,SMG7,RABGAP1L,PID1,NUP214,LRRC23" Drug 5941_UP H-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MAPT,ADCY2,APBB1,GAS7,BCAS1,SLC1A7,WDTC1,EMC1,GART,ALDH1L1,NEURL1,CHRNB2,CTNND2,KCNMA1,ATN1,SIDT2,LRRC23,RASGRP2" Drug 3941_DN Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "WLS,NDRG2,KIAA1109,FHL1,APBA2,BCAN,MSR1,DLL3,CDC42,ZFYVE9,MICAL1,SDC3,MAPK8,PARD6A,RALGDS,ATN1,LRRC23,RASGRP2" Drug 1884_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "MBP,SYNDIG1,PLA2G6,BCAN,CADM3,PHLDB1,MYRF,CACNA1A,NPPA,OMG,KCNK10,CDH8,ZMYND8,DUSP26,CAMKV,PACSIN1,CRMP1,RASGRP2" Drug 7452_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "PAQR6,MDM4,NDRG2,CLIP1,PLA2G6,SEMA6A,C1orf61,SLC2A5,SLC6A9,ALDH4A1,SOX10,ALDH1L1,SLCO1C1,WSCD1,SPX,PROX1,PTAFR,ATN1" Drug 3840_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.16E-04 1.00E+00 2.07E-02 2.27E-01 18 195 "EMID1,KIAA1109,GAS7,WDTC1,BTRC,GPR19,NUMA1,IGSF1,EDRF1,SNX27,RAD52,RALGDS,ATG16L1,DTNA,RGS10,EFNA3,ROM1,LRRC23" Drug 2694_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.19E-04 1.00E+00 2.07E-02 2.27E-01 17 179 "TESK2,ASRGL1,PALLD,ZSWIM8,NCAM1,RGL1,RND1,CAMSAP2,GOLGB1,INA,PCDH9,CCSER2,KIAA0513,RIMS3,DNAJC6,TTLL7,EFNA3" Drug 6951_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.19E-04 1.00E+00 2.07E-02 2.27E-01 17 179 "FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,VAMP1,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,RASGRP2" Drug CID000002414 AC1L1DME Stitch 8.31E-04 1.00E+00 2.10E-02 2.30E-01 10 76 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,CHRM1,VCAN" Drug CID000006636 Polychlorinated biphenyls Stitch 8.41E-04 1.00E+00 2.11E-02 2.31E-01 6 29 "PC,ANLN,PRKCG,PKN2,PRKCZ,TOX" Drug CID000010101 ketobemidone Stitch 8.41E-04 1.00E+00 2.11E-02 2.31E-01 6 29 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000114827 LY354740 Stitch 8.44E-04 1.00E+00 2.11E-02 2.31E-01 8 51 "GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3" Drug CID000000888 magnesium Stitch 8.55E-04 1.00E+00 2.11E-02 2.31E-01 76 1326 "MAG,ADGRV1,NDRG2,F3,ADCY2,RYR1,ADORA1,TUBB4A,ACTL6B,FOXM1,ANXA7,DGKZ,GPAM,DGKD,RPH3A,SLCO1A2,DNAH17,MTR,SNAP25,ATP1A2,ATP1A3,FYN,ATP2B2,NMNAT2,ADHFE1,RND1,ABCC8,NEU4,DIRAS1,NUCB1,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRIN1,OMG,GUCY1A2,P2RX7,AIFM1,PC,CDC42,TPM3,TPM4,PDE2A,PDE3B,PDE4B,PFKFB3,PHKG1,PMS2,PTPA,VCAN,PRKAB2,PRKACB,PRKCG,PKN2,PRKCZ,MAPK10,KLK6,ZBTB16,DPYSL5,PLPPR5,TUBB2B,PRTFDC1,COPS7A,KCNH1,AK5,KCNJ4,KCNJ9,KCNJ10,KCNMA1,PEX5,DNAH9,RAB5B,RTN4,NUP214" Drug ctd:C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester CTD 8.56E-04 1.00E+00 2.11E-02 2.31E-01 51 810 "SERPINA3,MBP,ECSIT,CLIP1,GRAMD1B,ADORA1,SEMA6A,BCAR3,ANK3,DOCK10,MAGI3,ST8SIA1,SLC1A2,SFMBT2,SLC6A9,NSG2,SLC14A1,GPR153,CAPRIN2,TNIK,NMNAT2,SMOC1,RHBDL3,WWC1,GPR19,CAMK2G,DDR2,VSTM2A,PSD3,USP2,TNFRSF1B,DCLK1,ADGRG1,NSD2,NXPH1,SNCAIP,MICAL2,VCAN,MASP1,DPYSL5,ELMO1,MED24,PTPRZ1,KCNH1,SV2A,TMCC2,KCNK2,DLG2,TTLL7,SEC61A2,FGFBP3" Drug CID005289285 Reidispongiolide C Stitch 8.63E-04 1.00E+00 2.11E-02 2.31E-01 23 280 "MAG,FGF1,SEMA6A,FOXG1,MOG,SLC1A2,SLC1A7,NCAM1,GFAP,NHLH1,CNTN2,NPPA,OMG,ZFP91,TNFRSF1B,JAM2,PMS2,KCNA1,KCNA6,DSCAM,RTN4,NUP214,EFNA3" Drug 5007_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "NDRG2,FHL1,FOXG1,CDC42BPA,BCAN,WDTC1,EML4,CCKBR,LILRA4,PDE3B,CNTN1,PACSIN1,PKN2,ARHGEF4,MAPK8,HP1BP3,KCND3,SV2A" Drug 3029_UP Dimethadione [695-53-4]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "MAPT,TUBB4A,KIAA1109,FHL1,AQP4,SLCO1A2,ASPH,WSCD1,TF,OPCML,USP2,INA,TJP1,HPSE2,PMEPA1,KCNMA1,SLC6A15,SEC61A2" Drug 4390_UP Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "GAS7,SLC1A7,SHANK2,DDX25,MYBPC1,PRUNE2,BRSK2,PDE1C,GPR37L1,PACSIN1,ATRNL1,VCAN,PTAFR,SV2A,ATN1,RASGRF1,USH1C,RCAN2" Drug 6171_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "EYA1,WLS,PPM1E,PALLD,NCAM1,GPR19,NRGN,PSD3,NEURL1,SERPINE2,FEZ1,CTNND2,RIMS3,DNAJC6,DLG3,RAB3IL1,NUP214,EEF1A2" Drug 325_DN radicicol; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ASIC1,FOXRED2,ANK2,DGKD,PKNOX2,CADM3,FXYD6,TF,OPCML,DAAM2,TMPRSS5,CCSER2,CP,SRGAP3,SNX27,DNAH9,EPB41L2,LRRC23" Drug 5063_UP Diprophylline [479-18-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "CEND1,RASA3,DOCK10,CGREF1,ATP1A3,ALDH1L1,SLCO1C1,ASTN2,KLHL4,CACNA1A,GPR17,HAP1,PTGDR2,MAPK10,PRDM2,RAB3IL1,DTNA,SIDT2" Drug 7049_DN AH6809; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "FHL1,ANK3,CCDC88A,ASPH,TNIK,GART,COLGALT2,NDUFA5,TNS1,RBFOX2,PLEKHB1,CHRNB2,NMT2,CHD1L,VCAN,FAM131B,SYTL2,DSCAM" Drug 3374_UP Aminophylline [317-34-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ADORA3,TUBB4A,SEMA6A,FHL1,SELL,DNAH17,SORCS3,ALDH1L1,NCDN,CDH8,PRMT8,CHI3L2,PLEKHB1,CHRNB2,NMT2,NECAB2,ARHGEF4,ST8SIA3" Drug 1267_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "BCAR3,BBOX1,PKNOX2,CGREF1,EMC1,PADI2,TNS1,CDH10,TPD52,PDE3B,NMT2,RNF14,PTAFR,PTCH1,DTNA,RET,SEC61A2,ABI2" Drug 4643_DN Iohexol [66108-95-0]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "MOBP,CDC42BPA,APC,PDE8B,ATP2B2,CADM3,NEUROD1,GPM6B,GPR17,NUMA1,GRIN1,CDH10,GPR37L1,CABP1,PEX5,RAD52,FAM13C,RGR" Drug 3826_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "TTYH1,EMID1,CEND1,ACTN2,NDRG2,ADORA1,APBB1,PKNOX2,ASTN1,SNAP25,ADGRB2,ACSBG1,ADGRL3,OMG,OPCML,PDE2A,CTNND2,TOX" Drug 4162_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ASIC1,MDM4,ADD3,ASPH,WDTC1,POPDC3,GNG4,EML4,PSD3,SNCAIP,SYNC,PTHLH,KCNK2,RAB3IL1,DTNA,RGS10,SSPN,EFNA3" Drug 3802_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "MAPT,RASA3,APBB1,RPH3A,NEUROD1,KAZN,BTRC,GPM6A,TCF7L2,GPR17,TNS1,PDE4B,MICAL1,CRMP1,TENM4,PARD6A,KCNMA1,RAB3IL1" Drug 4772_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "DPF1,NDRG2,APC,FYN,TNIK,KAZN,OMG,INA,CDH10,PLEKHB1,TENM4,OSBPL3,VCAN,RIMS3,KCND3,KCNJ4,KCNMA1,EFNA3" Drug 2510_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "AGT,PKNOX2,PDE8B,ALDH4A1,SOX10,NCAM1,TCF7L2,CRB1,GUCY1A1,LILRA4,NRXN2,VAV2,CABP1,MICAL2,MAPK10,KCNC1,BEND5,ROM1" Drug 5109_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ADORA1,AGT,APC,GAS7,SORBS1,SLC2A5,MLC1,GLS,GNG3,HAP1,TNS1,EDRF1,PROX1,PRDM2,PARP11,DTNA,ST8SIA3,RGR" Drug 5533_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "PLA2G6,AMPH,ANK2,ITSN1,GAS7,BCO1,MSR1,CCDC181,PSD3,CNTN1,MICAL1,FEZ1,MICAL2,PLPPR1,PRDM2,PTPRD,PTPRZ1,ELAVL4" Drug 4970_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "NDRG2,TUBB4A,KIAA1109,FOXG1,CDC42BPA,PKNOX2,CGREF1,GPR153,SLN,GAD2,NPAS3,AJAP1,CACNB2,PSD3,TGFBR3,RIMS3,PTAFR,SIDT2" Drug 6667_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ACHE,FGF1,DOCK10,SORBS1,CCDC181,GAD2,ADGRB2,NFASC,BTRC,DAAM2,PCDH9,PDE3B,PDE4B,CRMP1,KCNC1,KCND3,KCNMA1,DTNA" Drug 4597_UP Naringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "PLA2G6,C1orf61,NTNG1,SLC2A5,ASCL1,CADM3,MYRF,USP2,SERPINE2,CADM1,VAV2,ARHGEF4,EDRF1,RABGAP1L,ARNT2,RASGRF1,RGR,RGS10" Drug 3571_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ACTN2,ARID1A,PKNOX2,ASCL1,ATP1A2,GAD2,NEUROD1,VAMP1,ROBO3,USP2,TNS1,ASIC3,RIMS3,MAGI2,DTNA,SSPN,EFNA3,ELAVL3" Drug 4567_UP Cefixime [79350-37-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "CEND1,RTN1,PLA2G6,FOXG1,GAS7,SLC6A9,B3GAT1,ATP2B2,ARPP21,NCAM1,BTRC,PRUNE2,GRIN1,NRXN2,IFFO1,PLPPR4,RGS10,VWA5A" Drug 4331_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ACTN2,ASPH,GLS,GPM6A,NEURL1,PDE2A,ZMYND8,CA14,SULT4A1,SF1,PRKAB2,PKN2,MAPK8,PROX1,AK5,RABGAP1L,RAD52,ABCC9" Drug 3194_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "NDRG2,C1orf61,PKNOX2,DLL3,ATP2B2,LMO3,INKA2,POPDC3,NPPA,OMG,CDC42,SEZ6L,IFFO1,RGS6,PSD,PHYHIP,RALGDS,VWA5A" Drug 1479_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ACTN2,TUBB4A,PLA2G6,HPCAL4,FOXG1,NLGN1,SLC2A5,TAGLN3,ATP2B2,ZCCHC24,EMC1,ASTN2,WSCD1,MICAL1,ATRNL1,CTNND2,MAPK8,KCNMA1" Drug 5624_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "NDRG2,PLA2G6,BCAN,RPH3A,WDTC1,EMC1,SPART,NEUROD1,TGFBR3,TNS1,PDE3B,CHRNB2,SULT4A1,SDC3,PRDM2,RAB3IL1,ATN1,EFNA3" Drug 2528_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "APC2,ARID1A,MDM4,NDRG2,AGT,BCAR3,PDE8B,CCDC181,CADM3,INKA2,GNG4,TCF7L2,CCSER2,CTNND1,PTAFR,DLG3,RAB3IL1,SIDT2" Drug 5799_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "KLRC4,FABP7,AGT,C1orf61,GAS7,ATP1A2,ZSWIM8,ADGRB2,ACSBG1,GNG4,INA,PDE2A,CRMP1,ARHGEF4,DTNA,NUP214,LMO1,VWA5A" Drug 6021_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "EMID1,MDM4,SYBU,PKNOX2,ASCL1,CCDC181,WDTC1,CADM3,EMC1,PHLDB1,GLS,POPDC3,NUMA1,TGFBR3,PHKG1,MAPK8,NUP214,VWA5A" Drug 4808_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "FOXRED2,ITSN1,APBA2,SLN,POPDC3,GNAS,BTRC,CACNA1A,WSCD1,NUMA1,GRIN1,ZMYND8,PMS2,PTHLH,KCND3,TMCC2,DSCAM,EFNA3" Drug 3745_UP Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "BCAS1,SHANK2,DNAH17,GNG3,ADGRL3,INA,ADGRG1,SULT4A1,MAPK10,EDRF1,MAGI2,KCND3,RAD52,PARP11,ATN1,DSCAM,ST8SIA3,RASGRP2" Drug 5910_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "FOXG1,RASA3,SORBS1,PKNOX2,SLCO1A2,ALDH1L1,ASTN2,GNAS,GNG4,CDK5R2,CACNB2,GRIA4,GRIK2,PDE4B,CABP1,MAPK8,RASGRF1,VWA5A" Drug 6648_DN "Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "TMEM156,KIAA1109,PLA2G6,DOCK10,APC,TNIK,NCDN,BTRC,ZEB1,PCDH9,NMT2,CNIH3,SMG7,PARD6A,EFNA3,VWA5A,EN2,PLEKHO1" Drug 2440_DN Niridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "EMID1,FHL1,FOXG1,ITSN1,APC,RAP1GAP2,NCAM1,NDUFA5,NCDN,ADGRL3,CACNA1A,TCF7L2,RBFOX2,COL9A2,MAPK10,PTAFR,PTPRO,EFNA3" Drug 6364_UP CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "DPF1,ADORA1,NLGN4X,C1orf61,APBA2,PDE8B,DNAH17,ATP1A2,FXYD6,RGL1,GPM6A,PIK3CD,TENM4,RGS6,MICAL2,KCNMA1,FAM13C,USH1C" Drug 4629_DN Droperidol [548-73-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "FOXRED2,WDTC1,ADGRB2,ADGRL3,GPM6B,NUMA1,GRIK2,TNS1,PLEKHB1,NSD2,CHD1L,SF1,GON4L,RABGAP1L,RAD52,ATN1,BSDC1,RGS10" Drug 5689_UP Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "CDHR1,SYNDIG1,NDRG2,ADORA1,FGR,SORBS1,SLC2A5,FYN,NCAM1,MYRF,ADGRL3,CCKBR,PCSK2,PHKG1,RGS6,ARHGEF4,DPP6,RASGRF1" Drug 6633_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "ARID1A,PLA2G6,GAS7,SLCO1A2,BRINP2,TNIK,PHLDB1,GPM6A,TNS1,PDE3B,SPATA6,PTHLH,SMG7,DLG3,DTNA,PAK5,CAMK1G,VWA5A" Drug 4482_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "APC,BCAS1,SHANK2,ATP1A3,ALDH1L1,GPM6A,PC,TNS1,CDH8,PTGDR2,PLEKHB1,VAV2,MICAL2,FAM131B,ITIH2,ATN1,VWA5A,ROM1" Drug 5606_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "DPF1,FHL1,SLCO1A2,PHLDB1,POPDC3,SEMA4A,ADGRL3,NPPA,NUMA1,INA,ADGRG1,NECAB2,PTAFR,KCNC1,KCNK2,NKAIN1,BEND5,OLIG2" Drug 6367_DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.65E-04 1.00E+00 2.11E-02 2.31E-01 18 196 "EXTL1,MOBP,FOXG1,NLGN1,CCDC88A,B3GALT2,CADM3,CPLX2,AJAP1,ACSBG1,VAMP1,MYRF,GPM6A,GPM6B,NPPA,ZEB1,PTHLH,STMN4" Drug CID000004242 NSC-343257 Stitch 8.66E-04 1.00E+00 2.11E-02 2.31E-01 20 229 "SYT9,AGT,ZNF365,SHANK2,ATP1A2,ATP1A3,DNER,NPPA,NEU4,TF,TGFBR3,RBFOX2,PDE1C,VCAN,SDC3,PSD,PTHLH,NTM,PID1,SLC25A18" Drug 6939_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.72E-04 1.00E+00 2.12E-02 2.33E-01 17 180 "SYBU,FYN,ZCCHC24,RGL1,ACSBG1,GLS,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,DNAJC6,JAKMIP2,TMCC2,NAV2,EFNA3" Drug 6340_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.72E-04 1.00E+00 2.12E-02 2.33E-01 17 180 "SH3GL2,SORBS1,BRINP2,FYN,ZCCHC24,RGL1,GLS,KAZN,NUMA1,USP2,PCDH9,PIK3CD,DNAJC12,KIAA0513,JAKMIP2,PLPPR4,EFNA3" Drug CID004489307 AC1NB8R3 Stitch 8.96E-04 1.00E+00 2.13E-02 2.33E-01 19 213 "NLGN4X,FOXG1,ASRGL1,SLC1A2,ATM,GRIA1,CYB561A3,GRM3,CCKBR,PAH,HNRNPK,TLX1,NLGN3,NRXN1,HPR,PACSIN1,PYGM,ATN1,EN2" Drug ctd:D000661 Amphetamine CTD 8.98E-04 1.00E+00 2.13E-02 2.33E-01 15 149 "ASIC1,ACHE,F3,ANXA7,SLC6A9,GFAP,GRIA2,GRIN1,CCKBR,PDYN,CHRM1,PRKCG,PRKCZ,MAPK8,KCNA1" Drug CID000005631 AC1L1KS5 Stitch 9.15E-04 1.00E+00 2.13E-02 2.33E-01 26 334 "MAG,ADCYAP1R1,RYR1,AGT,SLC2A5,SLC14A1,ATP2B2,GNAS,CACNA1A,CACNA1E,NPPA,CACNB2,GRM3,KCNK10,PTGDR2,NTSR2,CHRM1,PIK3CD,VAV2,PRKACB,PRKCG,PSD,PLPPR5,PTHLH,ATN1,CACNG7" Drug 5597_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "PLA2G6,SHANK2,GPR153,ZCCHC24,CLASP2,ASTN2,SEMA4A,CAMK2G,PC,SYNC,ITIH2,SMG7,RABGAP1L,NKAIN1,ATN1,EFNA3,RBM12,VWA5A" Drug 204_UP sulfasalazine; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "CEND1,NDRG2,FHL1,GAS7,SLC1A2,ASCL1,WDTC1,ZCCHC24,BTRC,GRIN1,NEURL1,PADI2,ZMYND8,CADM1,DZIP3,ITIH2,KCND3,ATN1" Drug 5618_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "SYNDIG1,C1orf61,ITSN1,ASCL1,SLCO1A2,AJAP1,WSCD1,GPM6A,TF,NEURL1,PC,LILRA4,FLRT1,MAPK10,TOX,TTLL7,VWA5A,EN2" Drug 6402_DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,MDM4,APBA2,CCDC88A,ATP1A3,GAD2,ADGRB2,GLS,CACNA1A,GPM6B,SPATA6,PACSIN1,MAPK8,KCNK2,ATN1,USH1C,RGS10,VWA5A" Drug 4739_UP Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MAPT,RASA3,APBA2,APC,TAGLN3,DLL3,SNAP25,GAD2,ARPP21,GLS,KCNK10,TNS1,ST8SIA5,SYNC,TMCC2,KCNMA1,VWA5A,ELAVL3" Drug 1749_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MBP,PAQR6,ADORA1,BCAN,ASCL1,PDE8B,WDTC1,ADGRB2,ALDH1L1,CACNA1A,GRIN1,LILRA4,DUSP26,PACSIN1,TMCC2,ATN1,CAMK1G,NUP214" Drug 6619_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ARID1A,ADCY2,NLGN4X,SCN3A,FGF1,PLA2G6,ANK2,SORBS1,SLC1A7,ASCL1,ASTN1,ATP1A3,TNIK,PHLDB1,GPR19,OLR1,VCAN,PID1" Drug 3319_UP Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MDM4,RYR1,APC,BCAN,WDTC1,GAD2,ZSWIM8,ALDH1L1,NDUFA5,GPM6A,BRSK2,GRIN1,KCNK10,CDH10,PACSIN1,ELMO1,KCNMA1,NUP214" Drug 5089_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "FGF1,CDC42BPA,GAS7,ST8SIA1,AQP4,BRINP2,SORCS3,ALDH4A1,ATP2B2,ASTN2,USP2,TLL2,PKN2,KCND3,RAD52,FAM13C,RGS10,RASGRP2" Drug 4673_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "SELL,BRINP2,GAD2,ADGRB2,NCAM1,PHLDB1,BTRC,HAP1,CHI3L2,PLEKHB1,NSD2,PTCH1,PRDM2,PLPPR4,RAD52,ATN1,DTNA,ELAVL3" Drug 337_UP felodipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,APBB1,ZNF365,AJAP1,KAZN,CACNA1A,CACNA1E,NRGN,TF,P2RX7,CHD5,MASP1,KCNMA1,PYGM,L1CAM,TTLL7,EFNA3,LRRC23" Drug 2826_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "EMID1,SYNDIG1,NDRG2,ADD3,RASA3,SORBS1,TAGLN3,WDTC1,ZCCHC24,GNG4,CACNB2,PCDH9,MICAL1,CTNND2,PTHLH,RAD52,SIDT2,ROM1" Drug 5049_UP Indomethacin [53-86-1]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,NDRG2,FGF1,DOCK10,SOX10,PHLDB1,NEUROD1,KLHL4,CACNA1A,GPR37L1,HPSE2,CHGA,CHI3L2,ZFYVE9,POU3F2,ITIH2,RAD52,RASGRP2" Drug 4093_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "APC,AQP4,PKNOX2,ATP1A2,CADM3,SOX10,GRIK3,TMEM257,HPSE2,CHD5,PROX1,KCND3,NTM,KCNJ4,DTNA,ST8SIA3,VWA5A,RASGRP2" Drug 3704_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MAPT,ADORA1,FGF1,SLC1A7,TAGLN3,ACSBG1,KAZN,NPPA,HAP1,OPCML,CHRNB2,MAPK10,PLPPR1,PTHLH,RABGAP1L,DSCAM,DTNA,VWA5A" Drug 6975_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "CDC7,APC,ATM,NASP,NCDN,ARHGEF7,GPR19,PADI2,CCSER2,CHD1L,MICAL2,RBPJ,RIMS3,DNAJC6,PARD6A,SUSD4,ARHGEF10L,EPB41L2" Drug 2618_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "FOXRED2,KIAA1109,ADGRB2,NPAS3,ALDH1L1,FGF17,VAMP1,TGFBR3,CDH8,PIK3CD,VAV2,CHD5,NOS1AP,PLPPR1,PTPRD,PEX5,SLC6A15,NUP214" Drug 5051_UP Roxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,DOCK10,PKNOX2,GFRA1,PHLDB1,VAMP1,PCDH9,PTGDR2,ZMYND8,HPSE2,ASIC3,PLCH2,ARHGEF4,MAPK10,RIMS3,CNIH3,PID1,RASGRF1" Drug 3832_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "C1orf61,SLN,INKA2,MYRF,WSCD1,OMG,OPCML,CCKBR,CHRNB2,PIK3CD,FLRT1,VAV2,NOS1AP,PTAFR,PTPRD,PTPRO,TMCC2,KCNK2" Drug 6490_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "APC2,CEND1,GAS7,PKNOX2,SLC6A9,MYH7,ADAM15,GFAP,FGF17,SEMA4A,HAP1,CAMK2G,PSD3,PTGDR2,KCND3,RAD52,RASGRF1,EFNA3" Drug 2988_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ABAT,MDM4,GRAMD1B,FHL1,FOXG1,AMPH,PDE8B,EMC1,GLS,PRUNE2,GPM6B,NPPA,CDH10,PTGDR2,TPM3,CRMP1,TOX,PTAFR" Drug 2759_UP Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "NDRG2,FHL1,FOXG1,RASA3,APBA2,WDTC1,GNG3,CDC42,GPR37L1,MICAL1,CRMP1,TENM4,MAPK10,PTHLH,TMCC2,KCNMA1,EFNA3,ELAVL3" Drug 3940_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "NDRG2,KIAA1109,PLA2G6,C1orf61,GAS7,MSR1,GPR153,ASPH,GAD2,RND1,CDC42,MAPK8,PLPPR1,KCNMA1,ATN1,DSCAM,NUP214,LRRC23" Drug 4160_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,ADORA1,FHL1,PDE8B,GPR153,ASPH,ZCCHC24,POPDC3,GNG4,ASIC3,NMT2,SNCAIP,IGSF1,ITIH2,TMCC2,DNM2,SIDT2,VWA5A" Drug 4347_DN Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MAPT,MDM4,RASA3,APBA2,GPR153,ATM,WSCD1,ZEB1,NEURL1,MAGI1,CHRNB2,CADM1,SMG7,RABGAP1L,DLG3,KIF2A,DTNA,EFNA3" Drug 4610_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ACTN2,C1orf61,GAS7,SLC1A6,B3GALT2,KLHL4,PRUNE2,GPM6B,ADAMTS8,POU3F2,RGS6,MICAL2,CHD5,MAGI2,RABGAP1L,RASGRF1,DTNA,ABCC9" Drug 2536_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,NDRG2,GRAMD1B,CDC42BPA,DOCK10,GART,GNG3,ADGRL3,GPM6B,ZEB1,CAMK2G,OLR1,TNS1,ZFYVE9,PRDM2,FAM13C,DTNA,EEF1A2" Drug 5759_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "HPCAL4,SORBS1,AQP4,TAGLN3,CCDC181,NDUFA5,INKA2,RND1,BTRC,ATF7,NPPA,CACNB2,CDH8,NCAN,DNAJC6,ABCC9,LMO1,LRRC23" Drug 3742_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "C1orf61,BRINP2,MLC1,VAMP1,MYRF,CACNA1A,GPM6A,CACNB2,DAAM2,PDE3B,CHRNB2,ARHGAP22,ZFYVE9,IFFO1,ITIH2,DTNA,RBM12,ELAVL3" Drug 5052_UP Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,ADORA1,PDE8B,GAD2,NCDN,PHLDB1,HAP1,BRSK2,GRM3,PDE3B,TMPRSS5,ARHGAP22,PIK3CD,FAM131B,RIMS3,JAKMIP2,RGS10,ELAVL3" Drug 2630_UP Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "RPH3A,SLC1A7,SLCO1A2,ALDH4A1,ZCCHC24,ALDH1L1,VAMP1,GNAS,NPPA,TNS1,CDH8,TPM3,CAMKV,PACSIN1,NOS1AP,PTHLH,DTNA,RGS7" Drug 4631_UP Josamycin [16846-24-5]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "TTYH1,SEMA6A,ASCL1,DDX25,ALDH4A1,ATP1A2,PHLDB1,GRIA1,NEURL1,SEZ6L,POU3F2,MICAL2,ITIH2,KCNMA1,DTNA,SIDT2,ROM1,RASGRP2" Drug 4266_UP Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "DPF1,NDRG2,APC,PKNOX2,KIF21B,NCAM1,ALDH1L1,ACSBG1,VAMP1,PRUNE2,BRSK2,DAAM2,ZMYND8,PMP2,PTAFR,KCND3,ATN1,RET" Drug 2322_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ADORA1,CDC42BPA,APC,SHANK2,CSPG5,ASPH,ASTN1,CADM3,ALDH1L1,SLCO1C1,TNS1,SERPINE2,ZFYVE9,SULT4A1,MAPK8,JAKMIP2,PTHLH,CNIH3" Drug 4138_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "WLS,ATP1A2,USP33,PHLDB1,GPM6A,CACNB2,OMG,OPCML,CDH10,CHI3L2,CHRNB2,SERPINE2,PACSIN1,PLCH2,KCNMA1,RAB3IL1,ATN1,SSPN" Drug 5767_UP Retinoic acid [302-79-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "EMID1,ADCY2,ADORA1,ADORA3,BCAS1,SLCO1A2,CADM3,RND1,VAMP1,MYRF,GPM6A,DCLK1,GPR37L1,SLC22A6,COL9A2,FAM131B,SLC17A6,ATN1" Drug 3781_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "GAS7,CGREF1,CSPG5,SLN,GAD2,COLGALT2,NDUFA5,ROBO3,BTRC,HAP1,NEURL1,PCDH9,PTPA,PRKAB2,RIMS3,SMG7,DLG3,RAD52" Drug 3069_UP Butylparaben [94-26-8]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ABAT,ARID1A,BCAR3,FHL1,AMPH,SORBS1,PDE8B,CADM3,NAP1L2,HRH3,TPD52,DUSP26,CCSER2,EDRF1,KIAA0513,RAD52,ELAVL3,LRRC23" Drug 401_UP LY294002; Up 200; 10uM; ssMCF7; HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "SYNDIG1,C1orf61,AMPH,GAS7,BCAS1,NMNAT2,SPART,KLHL4,ACSL6,CACNB2,HAP1,INA,TLL2,TNS1,MASP1,PMEPA1,LPAR6,LRRC23" Drug 2438_UP Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "CEND1,ADORA1,AGT,SLC2A5,CAMSAP2,GPM6B,TCF7L2,CHGA,CCSER2,ST8SIA5,ARHGEF4,CTNND1,CTNND2,EDRF1,MASP1,DLG3,NUP214,LRRC23" Drug 314_UP sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "FGR,ANK1,GAS7,SLC6A9,CADM3,NMNAT2,GFAP,ADGRL3,CAMK2A,P2RX7,GUCY1A1,CHRM4,PIK3CD,VCAN,MAPK8,PTPRD,RABGAP1L,SUSD4" Drug 6399_UP C75; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "EXTL1,PLA2G6,HPCAL4,C1orf61,DOCK10,APC,DNAH17,BRINP2,ALDH4A1,GAD2,ZSWIM8,CDK5R2,CA14,RAB3IL1,BEND5,TTLL7,SEC61A2,PLEKHO1" Drug 5750_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "TTYH1,NDRG2,TRIM46,RASA3,APBB1,SLC8A2,INKA2,PCDH9,CDH8,CDH10,CHI3L2,PLEKHB1,SNCAIP,ITIH2,PLPPR4,KCND3,RET,ELAVL3" Drug 375_DN tamoxifen citrate; Down 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "NDRG2,APC,NSG2,ASCL1,FYN,CADM3,GAD2,B4GALNT1,EMC1,VAMP1,KAZN,GRIN1,OPCML,TNR,SEZ6L,IFFO1,SRGAP3,KCNJ10" Drug 5874_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "TUBB4A,FGF1,APC,RPH3A,SLC1A7,PKNOX2,WDTC1,LILRA4,CHI3L2,ASIC3,JAM2,ARHGAP22,MAPK10,JAKMIP2,STMN4,PARD6A,ATN1,SIDT2" Drug 482_DN celecoxib; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "RBM10,GAS7,EMC1,GJB1,TMEM151B,NEURL1,TNS1,SEZ6L,JAM2,MAPK8,KCNC1,KCND3,KCNK2,DSCAM,SIDT2,EFNA3,RCAN2,RASGRP2" Drug 1109_UP 3-hydroxy-(D/L)-kynurenine; Up 200; 9.2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "RABEPK,CLIP1,ADD3,FOXRED2,ASRGL1,URGCP,MADD,CAMSAP2,ATP13A2,PADI2,RBFOX2,UBTF,PRKACB,CTNND2,DLG3,WIPF2,DTNA,NUP214" Drug 5252_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,MOBP,NLGN1,SLC1A7,PKNOX2,ATM,KIF21B,CADM3,GAD2,ZSWIM8,INKA2,PRUNE2,CHRNB2,SDC3,ARHGEF4,PTAFR,DTNA,VWA5A" Drug 3524_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ADORA1,SYBU,PKNOX2,ASTN1,FYN,CADM3,ALDH1L1,GNAS,NUCB1,GUCY1A2,SEZ6L,PLEKHB1,ZFYVE9,KCND3,RABGAP1L,KCNMA1,RAB3IL1,RASGRP2" Drug 6174_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "APC2,ADORA1,SELL,PDE8B,TAGLN3,ATP2B2,SLCO1C1,BTRC,GUCY1A2,PADI2,KIAA0513,SYTL2,KCNA1,KCNA2,KCNH1,KCNK1,ATN1,LMO1" Drug 2237_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "AMPH,GAS7,SOX10,GAD2,ACSBG1,KAZN,GNG3,NPPA,TNS1,HPSE2,PACSIN1,VCAN,ITIH2,KCNMA1,RAB3IL1,NUP214,TTLL7,RCAN2" Drug 3339_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "FABP7,ADORA1,KIAA1109,FHL1,MOBP,RASA3,GAS7,SLC1A7,CCDC88A,WDTC1,RND1,PDE3B,CHRNB2,PLCH2,KCNJ4,RAD52,RASGRF1,RGS10" Drug 6198_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "SEMA6A,MOBP,APC,PDE8B,GPR153,ZCCHC24,ZSWIM8,FGF17,GLS,BTRC,NPPA,ATP13A2,CHI3L2,SULT4A1,DZIP3,PRDM2,DLG3,NUP214" Drug 3040_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "APC2,NLGN1,PDE8B,PRUNE2,CAMK2A,DDR2,GRIK2,GUCY1A1,HPSE2,CHI3L2,RGS6,CHD5,DZIP3,TOX,PLPPR1,MAGI2,KCNK1,ELAVL4" Drug 2922_UP Epitiostanol [2363-58-8]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "MBP,FOXRED2,C1orf61,CDC42BPA,PDE8B,NAP1L2,RAP1GAP2,GJB1,ATF7,DAAM2,CNTN1,NECAB2,DZIP3,MAPK8,MAGI2,ST8SIA3,SEC61A2,RASGRP2" Drug 3849_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ASIC1,C1orf61,GPR153,BRINP2,ALDH4A1,INKA2,GANAB,FAM168A,KAZN,ZEB1,NUMA1,CELF3,PDE3B,ZFYVE9,FADS2,ATN1,SEC61A2,EN2" Drug 5488_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "ABAT,ADCY2,RASA3,SLN,ASTN2,SEMA4A,GPM6B,NPPA,NUMA1,TGFBR3,KCNK10,TNS1,ZMYND8,CNTN1,VCAN,EDRF1,CNIH3,SRGAP3" Drug 4222_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-04 1.00E+00 2.13E-02 2.33E-01 18 197 "KIAA1109,PKNOX2,ARPP21,KAZN,ADGRL3,ADAMTS8,SPX,TIE1,PTGDR2,SEZ6L,GPR37L1,NRXN2,KCNC1,ATN1,RASGRF1,DTNA,RGR,LRRC23" Drug CID000001189 NSC18930 Stitch 9.22E-04 1.00E+00 2.13E-02 2.33E-01 10 77 "ADAR,ADARB2,ADORA1,PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,PYGM" Drug ctd:D024505 Tocopherols CTD 9.22E-04 1.00E+00 2.13E-02 2.33E-01 10 77 "FGF1,SNCB,ATP1A2,CPLX2,VAMP1,CAMK2G,GRIA2,GRIN1,PTPRO,SV2A" Drug 4444_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 2.13E-02 2.33E-01 16 165 "ABAT,F3,SORBS1,FYN,RGL1,RND1,GLS,PCDH9,CADM1,DNAJC12,SYTL2,DNAJC6,JAKMIP2,PLPPR4,EFNA3,VWA5A" Drug CID000009905 trifluoroacetophenone Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "ACHE,F3,ADHFE1,KCNH1" Drug CID000007424 34 d Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "GPR162,RBPJ,PSMD13,RAB3IL1" Drug CID000024268 NaNO3 Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "WAC,PLA2G6,CCDC88A,DDR1" Drug CID000166765 carAa Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "ADAR,ADARB2,GRIK4,CA10" Drug CID006439089 BWA1433 Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "ADAR,ADARB2,ADORA1,ADORA3" Drug CID005288002 C-X6 Stitch 9.51E-04 1.00E+00 2.13E-02 2.33E-01 4 12 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000000761 5'-GMP Na2 Stitch 9.56E-04 1.00E+00 2.13E-02 2.33E-01 26 335 "SORBS1,NRG3,NMNAT2,NPPA,CACNB2,GUCY1A2,GUCY1A1,TJP1,MAGI1,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,TJP2,MAPK8,MAPK10,ITIH2,PRTFDC1,KCNA2,KCNA4,DLG2,DLG3,DNM2,ATL1,SSPN" Drug CID000077802 3-chlorobenzylamine Stitch 9.59E-04 1.00E+00 2.13E-02 2.33E-01 11 91 "SYT9,RASA3,RPH3A,SNAP25,VAMP1,SYT4,CACNA1E,SYT6,SYTL2,KCNMA1,RGS10" Drug CID000003044 NSC95943 Stitch 9.59E-04 1.00E+00 2.13E-02 2.33E-01 11 91 "ADAR,ADARB2,ADCY2,ADCYAP1R1,ADORA1,ADORA3,PLA2G6,APC,SLC1A2,PRKACB,PRKCG" Drug CID000007045 Quinoxaline Stitch 9.64E-04 1.00E+00 2.13E-02 2.33E-01 8 52 "F3,ADORA3,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3" Drug 2264_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAG,NDRG2,TUBB4A,CCDC88A,ASCL1,ATP2B2,WSCD1,ZEB1,PSD3,TNS1,PLEKHB1,ZFYVE9,PTCH1,ITIH2,PARD6A,KCND3,SRGAP3,GNE" Drug 4830_UP Piperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ACTN2,C1orf61,ANK1,APC,MSR1,CCDC88A,MYH7,NCAM1,POPDC3,WSCD1,GPM6A,PDE1C,PIK3CD,SULT4A1,ATN1,FAM13C,EN2,RASGRP2" Drug 5452_DN Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "PLA2G6,FHL1,SLC1A7,WDTC1,SPART,NDUFA5,INKA2,GPM6B,FADS2,MED1,SDC3,CTNND2,MAPK8,GON4L,PEX5,RAD52,RGS10,ZNF248" Drug 5838_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "FOXG1,TAGLN3,ATP2B2,SCN3B,WDTC1,ACSBG1,NUCB1,CHI3L2,SULT4A1,COL9A2,PLCH2,VCAN,STMN4,KCND3,KCNJ9,ATN1,NUP214,RGS7" Drug 2512_UP Anabasine [494-52-0]; Up 200; 24.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "SLC6A9,ASPH,CCDC181,ATP1A3,CADM3,NDUFA5,GLS,WSCD1,TCF7L2,GPR19,TMEM257,CHRNB2,NRXN2,VAV2,CRMP1,PHYHIP,KCND3,ST8SIA3" Drug 3990_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "SELL,APC,SLC1A7,SLC6A9,DNAH17,ALDH4A1,WDTC1,TNIK,B4GALNT1,GPR19,NUMA1,SIRPA,LRP8,RALGDS,ATN1,DTNA,SIDT2,LRRC23" Drug 4981_UP Harpagoside [19210-12-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,NDRG2,MOBP,APBA2,ASPH,RGL1,VAMP1,WSCD1,CACNB2,ZEB1,CAMK2G,NUMA1,PIK3CD,MICAL2,PTHLH,DSCAM,SIDT2,RPRD1A" Drug 3909_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,APBA2,AQP4,ATP1A3,ALDH1L1,ACSBG1,VAMP1,GPM6A,USP2,TNFRSF1B,CDC42,CNTN1,CABP1,PTAFR,RABGAP1L,TMCC2,ST8SIA3,ELAVL3" Drug 4956_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "NDRG2,ADORA1,KIAA1109,SLC2A5,PKNOX2,SHANK2,GAD2,RGL1,AJAP1,WSCD1,GPM6B,OMG,TNS1,PRMT8,PIK3CD,KCND3,VWA5A,OLIG2" Drug 1518_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,CEND1,MOBP,SLC1A2,WDTC1,SPART,PHLDB1,GPM6B,OPCML,DAAM2,CDH8,SPATA6,VCAN,RIMS3,RAB3IL1,RAD52,SEC61A2,SIDT2" Drug 6296_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,ARID1A,TESK2,FGF1,AQP4,SLC1A6,SLC1A7,ASTN1,HAP1,NUMA1,NOS1AP,RIMS3,PTCH1,NTM,RAB3IL1,PAK5,RGS10,EFNA3" Drug 2521_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "KCNIP2,FHL1,FOXG1,SLCO1A2,ALDH4A1,ACSBG1,PCDH9,PDE1C,PRMT8,CHRNB2,ZFYVE9,SULT4A1,MAPK10,ITIH2,KCNJ4,DLG3,PAK5,SIDT2" Drug 4383_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "SYNDIG1,GAS7,SNAP25,ZCCHC24,KIF21B,MYH7,NCAM1,RGL1,CDK5R2,WSCD1,KCNK10,CDH8,DUSP26,CABP1,VCAN,NCAN,TTLL7,ELAVL3" Drug 1538_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,ADORA1,AMPH,BCO1,SLN,ATM,AJAP1,TCF7L2,PSD3,NEURL1,ASIC3,CRMP1,ECE2,RIMS3,RABGAP1L,SLC17A6,BSDC1,SIDT2" Drug 2812_UP Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "RYR1,SEMA6A,ANK1,SLC1A2,SHANK2,CADM3,GAD2,MYH7,NDUFA5,GNG4,HAP1,CHRNB2,RGS6,MAPK8,RAB3IL1,CRTAC1,VWA5A,ROM1" Drug 5443_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,TUBB4A,HPCAL4,MOBP,ANK1,APC,DLL3,TNIK,KIF21B,GLS,PRUNE2,PCDH9,ADGRG1,SULT4A1,CA10,PTHLH,PTPRO,ATN1" Drug 2345_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "RBM10,TMEM156,PLA2G6,C1orf61,PKP4,GPR153,KIF1B,TCF7L2,NUMA1,GRIK2,USP2,ZFYVE9,CNTN1,PTPA,CTNND1,PTAFR,SMG7,DTNA" Drug 316_UP flufenamic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MBP,ANK1,GAS7,DNAH17,MYBPC1,NMNAT2,MYH7,BTRC,CACNA1A,CACNA1E,OPCML,SEZ6L,PRMT8,CHGA,JAM2,CAMKV,TJP2,OSBPL3" Drug 4816_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,TUBB4A,PLA2G6,SEMA6A,FHL1,KIF21B,CADM3,VAMP1,GPM6B,PSD3,OMG,NEURL1,MAPK8,NOS1AP,RIMS3,PLPPR1,MAGI2,TMCC2" Drug 7232_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ACTN2,NDRG2,KIAA1109,FHL1,C1orf61,GAS7,SYBU,CAPRIN2,RCOR3,ATP1A3,GART,ALDH1L1,BTRC,ADGRG1,MAPK8,SMG7,PEX5,RGS10" Drug 3721_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "KLRC4,ADORA1,APBB1,RPH3A,PDE8B,SLCO1A2,SCN3B,CPLX2,INKA2,NEUROD1,ACSBG1,GPR19,OLR1,PDE2A,PDE3B,MAPK10,RABGAP1L,NUP214" Drug 2901_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,ADORA1,C1orf61,ANK3,MSR1,GPR153,GJB1,GNG3,GPM6B,INA,CDH8,MAGI1,JAM2,CABP1,RNF14,MAPK8,NOS1AP,RGS10" Drug 3576_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,MAPT,APBA2,APC,PDE8B,ASPH,ZCCHC24,BTRC,CACNB2,ZEB1,TGFBR3,ZMYND8,SULT4A1,PACSIN1,NOS1AP,GON4L,JAKMIP2,DSCAM" Drug 4258_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "RTN1,SCN3A,AQP4,ATP1A2,B3GALT2,ARPP21,NFASC,NUMA1,GRIA1,P2RX7,SEZ6L,GPR37L1,CHGA,HPCA,VAV2,NOS1AP,PRDM2,KCNH1" Drug 2816_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "C1orf61,SLC1A7,PKNOX2,DNAH17,DLL3,SLN,ZCCHC24,GAD2,SLCO1C1,WSCD1,CACNB2,ASIC3,SULT4A1,CA10,PRDM2,PTPRD,RAB3IL1,PARP11" Drug 6148_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CEND1,ACTN2,BCAR3,SELL,PKNOX2,GPR153,PHLDB1,GPM6B,GRIN1,OPCML,PTGDR2,TPM3,CABP1,PSMD13,KCNJ4,ATN1,PAK5,ELAVL3" Drug 4446_UP 2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "KLRC4,PKP4,ASTN1,ATM,GLS,CDK5R2,ADGRL3,CACNA1A,TNS1,SULT4A1,SPATA6,MAPK8,MAGI2,SMG7,RABGAP1L,SUSD4,FAM13C,RET" Drug 2910_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EYA1,PLA2G6,BCAN,MSR1,ASPH,SLN,ALDH4A1,PALLD,RAP1GAP2,GNG4,MYRF,GPM6B,CDH10,CTNND2,PARD6A,RAB3IL1,ST8SIA3,SEC61A2" Drug 6702_UP Niacin [59-67-6]; Up 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CEND1,ANK1,APC,SLC6A9,FYN,NEUROD1,SLCO1C1,GPM6A,TF,P2RX7,CHI3L2,PMP2,MICAL2,SDC3,RALGDS,FAM13C,ABCC9,RASGRP2" Drug 2760_UP Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ACTN2,NDRG2,C1orf61,RASA3,RPH3A,BCO1,PKNOX2,ASCL1,GAD2,NRGN,CDH10,PDE3B,FADS2,PACSIN1,SYNC,PTAFR,MAGI2,VWA5A" Drug 3767_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,SYNDIG1,PAQR6,CEND1,AMPH,DOCK10,SHANK2,ALDH1L1,GNG3,TF,CHI3L2,IFFO1,FEZ1,MAPK8,PTAFR,ITIH2,PRDM2,KCNK2" Drug 4333_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ACTN2,MDM4,DOCK10,ASPH,B3GAT1,GPM6A,GPM6B,CACNB2,NUMA1,CADM1,PRRX1,MED1,SF1,PRKAB2,MAPK8,SMG7,KCNMA1,RET" Drug 6722_UP Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "AMPH,PKP4,APC,SEMA4A,HAP1,TNS1,PDE3B,CHI3L2,NRXN2,COL9A2,CRMP1,CTNND2,NTM,ATN1,FAM13C,ST8SIA3,SIDT2,LRRC23" Drug 6616_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "FGF1,PLA2G6,AMPH,NTNG1,GAS7,KIF21B,GAD2,NCAM1,ALDH1L1,PRUNE2,PADI2,CDH10,LILRA4,VAV2,CNTN1,ARHGEF4,EDRF1,PTPRD" Drug 2332_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,GRAMD1B,ZSWIM8,KIF1B,ARHGEF7,TCF7L2,NUMA1,PSD3,CDC42,NECAB2,PPP2R5C,RGS6,VCAN,KCNC1,RABGAP1L,SIDT2,ABI2,VWA5A" Drug 4074_UP Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CEND1,RYR1,AQP4,MSR1,SNAP25,MYRF,CNTN2,GPM6A,TNS1,HPSE2,NRXN2,VAV2,ECE2,PTCH1,KCND3,KCNJ4,ARNT2,USH1C" Drug 2294_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MOBP,GAS7,SHANK2,GPR153,GAD2,INKA2,GLS,TNS1,SEZ6L,TPM3,PDE4B,KIAA1549L,FADS2,PTCH1,KCND3,ATN1,ABCC9,LPAR6" Drug 5435_UP Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MBP,CEND1,ACTN2,TRIM46,APBA2,GAS7,ATP2B2,WDTC1,CADM3,RND1,GLS,CDH8,PCSK2,ADGRG1,VAV2,RIMS3,JAKMIP2,RAD52" Drug 5500_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,APC2,ADORA1,FOXG1,SLC2A5,COLGALT2,GPM6B,NRGN,HAP1,TMEM151B,NUCB1,CAMKV,ATRNL1,VCAN,IGSF1,RGS7,EFNA3,LRRC23" Drug 487_UP WY-14643; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,MAPT,MBP,NDRG2,MOBP,ANK1,PKNOX2,ASCL1,CADM3,CAMSAP2,MYRF,WSCD1,CDH10,TMPRSS5,PIK3CD,PACSIN1,MAPK8,STMN4" Drug 5805_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,C1orf61,APC,PKNOX2,TAGLN3,EMC1,ALDH1L1,CDK5R2,CDH8,SEZ6L,ARHGAP22,CNTN1,COL9A2,CRMP1,CTNND2,NKAIN1,PID1,ATN1" Drug 6408_DN valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,ADORA1,SLC1A7,ALDH4A1,MYRF,GPR17,GPR19,PDE3B,ZMYND8,MICAL2,DZIP3,MAPK8,EDRF1,PEX5,RALGDS,DSCAM,EFNA3,PLEKHO1" Drug 4134_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "SYNDIG1,ACTN2,ATP1A2,PHLDB1,WSCD1,PAX6,PCDH8,SEZ6L,ACOT7,CHRNB2,ZFYVE9,SRGAP3,KCNMA1,RAB3IL1,ATN1,RGS10,SSPN,RCAN2" Drug 6384_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,MDM4,GAS7,SLC1A2,SOX10,AJAP1,GNG4,MYRF,TNS1,PIK3CD,POU3F4,VCAN,ARHGEF4,MAPK8,PTPRO,TMCC2,RGS7,EFNA3" Drug 5076_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,ACTN2,DOCK10,PKNOX2,ADGRB2,SPART,PHLDB1,CACNA1A,CDH10,KIAA1549L,VCAN,MAPK10,FAM131B,TOX,KCNA4,PID1,ST8SIA3,RGS7" Drug 3723_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,EMID1,NDRG2,HPCAL4,MOBP,RASA3,NTNG1,GAS7,B4GALNT1,VAMP1,PDE2A,CHI3L2,CADM1,MAGI2,DTNA,NUP214,ST8SIA3,RGR" Drug 3727_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "WAC,FGF1,ANK3,SLN,WDTC1,B4GALNT1,ADGRB2,MLC1,GNG4,CACNA1A,GPM6A,VAV2,MAPK8,PTCH1,PLPPR1,AK5,KCNMA1,DTNA" Drug 3973_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,SEMA6A,ASIC4,MOBP,PDE8B,SNAP25,NMNAT2,LMO3,PHLDB1,GRIN1,PCDH8,CDH10,PTGDR2,PIK3CD,SNCAIP,NOS1AP,MASP1,DNAH9" Drug 5080_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "FOXRED2,AGT,DOCK10,AQP4,ASCL1,CGREF1,CCDC181,CADM3,PHLDB1,NEUROD1,ACSBG1,TNS1,HPSE2,VAV2,CABP1,TOX,PID1,RGR" Drug 4265_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ABAT,SEMA6A,BBOX1,ASCL1,ATP2B2,MYH7,INKA2,SLCO1C1,ACSBG1,PRUNE2,NUMA1,GRIK3,GRIN1,SPX,ADGRG1,PHYHIP,KCNC1,RASGRF1" Drug 4839_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "SYNDIG1,KIAA1109,PLA2G6,C1orf61,BCO1,MSR1,PDE8B,SOX10,ZSWIM8,ACSBG1,SNCAIP,NCAN,PLPPR1,PRDM2,TMCC2,ATN1,SIDT2,EN2" Drug 2556_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EXTL1,CEND1,ANK2,RASA3,SYBU,MSR1,TAGLN3,ASPH,CCDC181,MYRF,PADI2,ASIC3,PHKG1,NRXN2,PMP2,CRMP1,MAPK10,MAGI2" Drug 3865_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ADORA3,KIAA1109,C1orf61,APBA2,GAS7,SLN,NCDN,ROBO3,PDE1C,FADS2,SULT4A1,CNTN1,MAPK10,PTCH1,PTPRO,TMCC2,KCNMA1,VWA5A" Drug 2712_UP Sulfameter [651-06-9]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "APC2,ADORA1,FHL1,RPH3A,PKNOX2,SHANK2,ASCL1,GPR153,TNIK,BTRC,ADGRL3,GPM6B,TMEM257,CHRM4,VAV2,DZIP3,ATN1,RASGRP2" Drug 2140_DN Seneciphylline [480-81-9]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CDC42BPA,APC,ZCCHC24,MLC1,GLS,GNG4,ZEB1,RBFOX2,UBTF,PTPA,MAPK8,RIMS3,PRDM2,RAB3IL1,RAD52,RET,ARHGEF10L,RASGRP2" Drug 4952_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "APC2,NDRG2,FABP7,ADORA1,KIAA1109,MOBP,ASPH,NDUFA5,OMG,KCNK10,LILRA4,FADS2,EDRF1,ITIH2,TMCC2,KCNMA1,RAB3IL1,SIDT2" Drug 2360_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAG,KIAA1109,FHL1,SLC1A7,KIF1B,GLS,CAMSAP2,GPR19,OLR1,PTGDR2,PDE4B,ST8SIA5,FEZ1,ARHGEF4,KIAA0513,PTPRE,KCNK1,FAM13C" Drug 7451_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "DPF1,MDM4,F3,BCO1,SLC6A9,CCDC88A,CGREF1,ALDH4A1,ZCCHC24,GLS,VAMP1,SEMA4A,CAMK2G,CHRNB2,SERPINE2,PIK3CD,NKAIN1,ATN1" Drug 5537_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,HPCAL4,SYBU,DNAH17,MYBPC1,CADM3,NPPA,CACNB2,GUCY1A1,EDRF1,PROX1,ITIH2,CNIH3,KCND3,TMCC2,ATN1,DSCAM,EPB41" Drug 3136_UP Trapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,MAPT,FOXRED2,FOXG1,AMPH,SLCO1A2,NPAS3,SLCO1C1,MLC1,BTRC,WWC1,GPM6A,PDE2A,DZIP3,KCNA1,SIDT2,EFNA3,LRRC23" Drug 1753_UP Noscapine [128-62-1]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,LGR4,NDRG2,ADCY2,ADORA1,CCDC88A,CADM3,GNAS,OLR1,PDE1C,PDE4B,ACOT7,PMS2,PACSIN1,FEZ2,OSBPL3,HP1BP3,VWA5A" Drug 440_DN "W-13, hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAPT,CDC42BPA,GAS7,DGKD,SHTN1,SMARCE1,SON,SPART,ATF7,NPPA,TNS1,SEZ6L,ARHGAP19,NMT2,DZIP3,MAPK8,RIMS3,RBM12" Drug 5211_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CEND1,SLC1A7,PKNOX2,CCDC88A,CSPG5,WDTC1,TNIK,USP2,ZFYVE9,CRMP1,PLCH2,MAPK8,SMG7,KCNK2,RAB3IL1,RAD52,EFNA3,EPB41L2" Drug 6089_DN Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,F3,FOXG1,APBA2,GAS7,BCAN,DNAH17,CADM3,NCDN,SEMA4A,BTRC,HAP1,CAMK2G,ZFYVE9,RIMS3,DTNA,SSPN,EFNA3" Drug 3215_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ARID1A,NDRG2,ASIC4,BCAS1,MSR1,SLC14A1,TAGLN3,ALDH4A1,ATP1A3,BTRC,OMG,SPX,TNS1,PDE1C,ADGRG1,ARHGEF4,ECE2,NOS1AP" Drug 4661_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAPT,AGT,SLC14A1,NDUFA5,PLEKHB1,UBTF,VCAN,CTNND2,TOX,KIAA0513,GON4L,SMG7,KIF2A,DTNA,NUP214,RGS10,TTLL7,ROM1" Drug 3074_UP Tyloxapol [25301-02-4]; Up 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "FHL1,ANK2,ANK3,APBB1,APC,SHANK2,PDE8B,GLS,PSD3,PADI2,ZFYVE9,CHD5,ARHGEF4,KIAA0513,KCND3,SSPN,ELAVL3,EPB41L1" Drug 6356_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAPT,TUBB4A,SLC2A5,SLC6A9,ATP2B2,PHLDB1,ADGRL3,KLHL4,NUCB1,NUMA1,GRIN1,ATP13A2,NMT2,SULT4A1,NECAB2,MAPK8,GON4L,DTNA" Drug 6034_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,ACTN2,FGF1,SEMA6A,ASIC4,SLC1A7,B3GAT1,SPART,NCAM1,PRUNE2,NPPA,HRH3,SEZ6L,PDE1C,SNCAIP,MAPK8,KCND3,VWA5A" Drug 5087_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "FGF1,SORBS1,SHANK2,PDE8B,DNAH17,ASTN1,GAD2,MYH7,INKA2,GPM6A,GPM6B,GUCY1A2,MAPK8,KCND3,RAD52,DTNA,NUP214,ST8SIA3" Drug 6158_DN Mephenytoin [50-12-4]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ASIC1,MOBP,ZCCHC24,EMC1,RAP1GAP2,ALDH1L1,GLS,TGFBR3,CDC42,PDE4B,ZMYND8,CCSER2,CRMP1,DZIP3,RIMS3,RABGAP1L,ABI2,VWA5A" Drug 6468_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "MAPT,F3,SEMA6A,BCAN,CAPRIN2,GLS,RBFOX2,PIK3CD,NMT2,DNAJC12,MICAL1,HP1BP3,RABGAP1L,DLG3,RAB3IL1,DTNA,SSPN,SIDT2" Drug 6044_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "CDHR1,SCNN1D,ASIC4,ANK1,RASA3,BCO1,ASCL1,TAGLN3,B3GAT1,SNAP25,CCDC181,ATP2B2,FGF17,ACSBG1,PRUNE2,NRXN1,POU3F2,PKN2" Drug 3755_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "ADORA3,MOBP,AQP4,CADM3,MYH7,NPAS3,LMO3,ALDH1L1,VAMP1,GNG4,DCLK1,SEZ6L,FEZ1,MAPK10,NOS1AP,SV2A,LMO1,VWA5A" Drug 6801_UP Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "EMID1,RASA3,DNAH17,ALDH4A1,ZSWIM8,EMC1,GPM6B,PSD3,TNS1,PIK3CD,FADS2,CRMP1,MICAL2,JAKMIP2,PRDM2,KCNMA1,PHC2,EFNA3" Drug 4464_DN 2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.73E-04 1.00E+00 2.13E-02 2.33E-01 18 198 "HPCAL4,CDC42BPA,ANK3,BCAN,ASPH,ATP1A3,VAMP1,GNG4,CACNB2,PADI2,ARHGAP19,CHRNB2,SLC22A6,POU3F2,MICAL2,EDRF1,KCNMA1,VWA5A" Drug ctd:D012601 Scopolamine Hydrobromide CTD 9.83E-04 1.00E+00 2.15E-02 2.36E-01 13 120 "MAPT,ACHE,ADORA3,AGT,MADD,GABBR1,ROBO3,HRH3,PDYN,CHRM1,CHRM4,CHRNB2,KCNA4" Drug 3142_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.86E-04 1.00E+00 2.16E-02 2.36E-01 17 182 "CEND1,ADORA3,FOXRED2,FGR,C1orf61,BCAS1,ASPH,SLN,SNAP25,ACSBG1,OMG,CAMKV,MAPK10,ZBTB16,KCNMA1,DTNA,SIDT2" Drug ctd:D014284 Triiodothyronine CTD 9.89E-04 1.00E+00 2.16E-02 2.37E-01 34 483 "MBP,WLS,RXRG,ADORA1,FGF1,PLA2G6,BCAR3,TRIM46,PAAF1,SLC1A2,SLC2A5,DLL3,ASPH,MYH7,ADAM15,KIF1B,NDUFA5,NKX2-2,NRGN,GRIK4,MFSD2A,PCSK2,SLC22A6,PIK3CD,FADS2,FLRT1,SULT4A1,PLD5,TUBB2B,KCNA1,KCNA4,PEX5,NUP214,TMEM100" Drug ctd:C412815 GW 4064 CTD 1.01E-03 1.00E+00 2.16E-02 2.37E-01 32 446 "SERPINA3,EMID1,SYT9,GAS7,SLC2A5,SHANK2,SLCO1A2,LGI3,ASTN1,ADGRA1,MEGF11,ADHFE1,CNDP1,VWCE,TF,MFSD2A,PC,PADI2,PCDH8,DUSP26,SLC22A6,DLGAP3,SEMA5B,NECAB2,ETNPPL,MAPK8,ZBTB16,KCNJ4,PID1,CAMK1G,RFX5,PIANP" Drug CID000126757 GYKI 53655 Stitch 1.02E-03 1.00E+00 2.16E-02 2.37E-01 6 30 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000003585 hemicholinium-3 Stitch 1.02E-03 1.00E+00 2.16E-02 2.37E-01 10 78 "ABAT,ACHE,AGT,SLC1A2,BCO1,GAD2,CHRM1,CHRNB2,POU3F2,SLC17A6" Drug 3230_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "F3,GAS7,SLC2A5,SLC14A1,DNAH17,ASPH,ALDH1L1,CACNA1A,GPM6B,PSD3,GRIK2,NEURL1,DAAM2,VAV2,ARHGEF4,PLPPR1,NTM,KCNMA1" Drug 6773_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ARID1A,TUBB4A,ASPH,B3GAT1,BCL2L2,ALDH1L1,RGL1,ASTN2,NUMA1,CHRNB2,PIK3CD,CNTN1,RGS6,RIMS3,PARD6A,DSCAM,RGS10,SSPN" Drug 4840_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC4,AMPH,APBA2,APC,PDE8B,WDTC1,ACSBG1,CACNB2,DAAM2,CDH8,PIK3CD,PMP2,CRMP1,MAGI2,KCNJ4,KCNMA1,SSPN,EFNA3" Drug 4159_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MOBP,FYN,AJAP1,ADGRL3,GUCY1A2,PCDH8,CHRNB2,FADS2,VAV2,SPATA6,POU3F4,MICAL2,VCAN,KCNC1,SV2A,ATN1,ST8SIA3,TTLL7" Drug 2625_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "PKNOX2,PDE8B,GPR153,ALDH4A1,GAD2,BCL2L2,GLS,VAMP1,ATF7,OMG,CELF3,PTGDR2,ZFYVE9,PIK3CD,VAV2,ELMO1,RAD52,NUP214" Drug 3096_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "RYR1,SLN,PALLD,GAD2,GNG3,GPM6B,NPPA,NEURL1,CHI3L2,ZFYVE9,EDRF1,SYTL2,ITIH2,KCNK1,DLG3,RAD52,EFNA3,RASGRP2" Drug 6525_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "NDRG2,PLA2G6,SEMA6A,SLC1A7,NPAS3,FGF17,AJAP1,NUMA1,FADS2,CNTN1,NSD2,TENM4,ARHGEF4,HP1BP3,ATN1,RASGRF1,DTNA,EFNA3" Drug 6654_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,NDRG2,MOBP,ANK2,RASA3,ASCL1,CCDC181,DKK3,VAMP1,SEMA4A,SEZ6L,PDE4B,HPSE2,NRXN2,SPATA6,IFFO1,PLCH2,TOX" Drug 2408_DN Disopyramide [3737-09-5]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "F3,GRAMD1B,TMEM156,ANK2,APC,WDTC1,FAM168A,CAMK2G,CDH10,RBFOX2,ZFYVE9,UBTF,MAPK8,PRDM2,RALGDS,RET,SIDT2,VWA5A" Drug 5090_UP Bufexamac [2438-72-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAG,MAPT,EMID1,AGT,SEMA6A,NTNG1,CCDC181,FYN,INKA2,CDH8,LILRA4,PDE4B,ZMYND8,ARHGEF4,PRDM2,SRGAP3,ST8SIA3,RGS10" Drug 3786_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "EMID1,ACTN2,MOBP,DOCK10,GAS7,SCN3B,SLCO1C1,NUMA1,OPCML,ADGRG1,SLC22A6,NMT2,SULT4A1,PTAFR,KCNC1,KCND3,PAK5,LMO1" Drug 2953_UP Lymecycline [992-21-2]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "GPR153,WDTC1,GNG3,WWC1,PADI2,RBFOX2,HMGB1,ZFYVE9,SULT4A1,PTPA,PTAFR,CA10,SMG7,RAB3IL1,ATN1,SEC61A2,LRRC23,RASGRP2" Drug 5481_UP Imidurea [39236-46-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MOBP,RPH3A,MSR1,TAGLN3,ATP1A3,KIF21B,SEMA4A,GNG3,CACNB2,ZMYND8,FADS2,VAV2,PACSIN1,HP1BP3,KCNJ10,RAB3IL1,EPB41L2,RASGRP2" Drug 4311_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "DPF1,ADORA3,ANK2,GAS7,SLC1A7,ALDH4A1,GPR162,KLHL4,PRUNE2,PCDH9,ADGRG1,MICAL1,SPATA6,IFFO1,ATN1,NUP214,RET,ELAVL3" Drug 4704_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "DPF1,ASIC1,PLA2G6,SELL,BCO1,SORCS3,GAD2,PHLDB1,GPM6B,CACNB2,GUCY1A2,TNS1,ASIC3,SULT4A1,CRMP1,KCNMA1,ATG16L1,SSPN" Drug 4399_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACTN2,KIAA1109,MOBP,BCAN,SLC1A2,ASCL1,OMG,TNS1,PDE1C,POU3F2,MAPK8,TOX,ITIH2,SRGAP3,RAB3IL1,RASGRF1,VWA5A,RASGRP2" Drug 4810_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAG,APBA2,AQP4,CADM3,AJAP1,CACNA1A,HAP1,GRIA4,NEURL1,CDC42,PMP2,PACSIN1,VCAN,ELMO1,KCNH1,ATN1,ST8SIA3,LMO1" Drug 366_DN Gleevec; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "FABP7,ANK2,ITSN1,IGSF9B,SNAP25,GAD2,EMC1,NPAS3,AJAP1,LUZP2,NEURL1,SEZ6L,HAPLN2,NRXN1,CAMKV,KCNA1,PTPRD,DTNA" Drug 6459_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "NDRG2,ADORA1,C1orf61,AQP4,ATP1A2,ATP2B2,BCL2L2,WSCD1,OPCML,GUCY1A2,ADGRG1,NSD2,PLCH2,ITIH2,KCNMA1,RALGDS,RGR,ELAVL3" Drug 4584_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,F3,SH3GL2,APC,FYN,ADGRB2,NDUFA5,NCDN,VAMP1,CACNA1A,TNS1,MAPK8,PROX1,SMG7,PARD6A,PID1,ELAVL3,EPB41L1" Drug 5485_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,SLC1A2,PKNOX2,SLN,ATP2B2,RGL1,GLS,SEMA4A,NRGN,HAP1,NUCB1,DAAM2,CHI3L2,PLEKHB1,MICAL1,KCND3,RAD52,LRRC23" Drug 2203_DN Karakoline [39089-30-0]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "KIAA1109,MOBP,ADAM15,SLCO1C1,VAMP1,CACNB2,CAMK2G,RBFOX2,UBTF,CCSER2,SULT4A1,EDRF1,KLK6,WIPF2,RAD52,EEF1A2,SIDT2,RASGRP2" Drug 3089_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "EXTL1,ACTN2,BCAR3,TRIM46,AMPH,CGREF1,GPR153,SLCO1A2,ATP2B2,MYT1L,GLS,OMG,TJP1,REPS2,NMT2,CNTN1,SYTL2,JAKMIP2" Drug 5280_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ADORA1,MOBP,FOXG1,GAS7,SNAP25,EMC1,ALDH1L1,POPDC3,CAMK2G,ADGRG1,CHI3L2,CABP1,IFFO1,CRMP1,SDC3,ITIH2,KCND3,DTNA" Drug 1472_UP Levodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "EMID1,ADCY2,FOXG1,CDC42BPA,APC,GAS7,ALDH4A1,ATP1A2,FYN,ALDH1L1,INKA2,GNG3,HAP1,CAMK2G,ZMYND8,CHI3L2,ASIC3,NCAN" Drug 5066_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "C1orf61,AMPH,SLC1A7,PKNOX2,ALDH1L1,SLCO1C1,KLHL4,CDH10,ZMYND8,HPSE2,CHGA,ZFYVE9,NRXN1,STMN4,RAD52,DTNA,CAMK1G,NUP214" Drug 6828_UP Piretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ADCY2,FHL1,FOXG1,SELL,GAS7,SORBS1,SHANK2,WDTC1,KIF21B,RGL1,WSCD1,OPCML,NEURL1,KCNK10,PDE4B,PTAFR,RBM12,RASGRP2" Drug 4132_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "AGT,DOCK10,AQP4,SLC14A1,SLCO1A2,ATP1A2,KIF21B,COLGALT2,INKA2,PHLDB1,SLCO1C1,OPCML,PDE1C,ZFYVE9,PTAFR,PTCH1,NTM,RAB3IL1" Drug 3835_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,TUBB4A,C1orf61,SELL,BRINP2,ATP2B2,SOX10,NEUROD1,SLCO1C1,CACNB2,PDE1C,CNTN1,POU3F4,PTHLH,ATN1,ELAVL3,EN2,RASGRP2" Drug 3169_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "SELL,CCDC88A,ALDH4A1,ATP1A3,FYN,SOX10,RND1,ROBO3,NPPA,LILRA4,OSBPL3,MAPK10,SYNC,TMCC2,ATN1,RASGRF1,DTNA,NUP214" Drug 6469_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "RYR1,FOXG1,SYBU,BCO1,ASCL1,BRINP2,ATP1A2,GAD2,PHLDB1,NEURL1,CHI3L2,FADS2,CABP1,CRMP1,VCAN,EDRF1,PTHLH,SSPN" Drug 4984_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ARID1A,NDRG2,BCAN,RPH3A,PHLDB1,NEUROD1,POPDC3,PSD3,SPX,KCNK10,CRMP1,SNCAIP,MAPK8,MAPK10,KCNMA1,RAD52,SIDT2,VWA5A" Drug 5048_UP Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,SCN3A,FGF1,DOCK10,APC,GAS7,MADD,PKNOX2,BRINP2,NEUROD1,ACSBG1,GNG4,ATF7,PDE4B,ASIC3,SRGAP3,PID1,RAD52" Drug 3485_DN Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "NDRG2,APC,ASPH,ALDH4A1,WDTC1,EMC1,SEMA4A,GNG4,NUMA1,ZFYVE9,SULT4A1,MICAL1,MAPK8,MAPK10,RABGAP1L,DSCAM,DTNA,LRRC23" Drug 6508_DN Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,C1orf61,SHANK2,PDE8B,ALDH4A1,ASTN2,GNG3,PSD3,CDH10,MAGI1,PIK3CD,DZIP3,MAPK8,EDRF1,JAKMIP2,RABGAP1L,RAB3IL1,DNM2" Drug 6403_DN valdecoxib; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,GAS7,CCDC88A,ATP1A3,ADGRB2,ROBO3,CACNA1A,PRUNE2,NPPA,ZEB1,CDC42,CDH8,SPATA6,VCAN,MAPK8,KCNK2,USH1C,EN2" Drug 5858_UP Delsoline [509-18-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACHE,RYR1,KIAA1109,FGF1,DKK3,WDTC1,ALDH1L1,TLL2,CDH8,SEZ6L,ASIC3,KCNA1,PTPRD,KCND3,SRGAP3,KCNMA1,BEND5,RASGRP2" Drug 3603_UP Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "PKNOX2,ASCL1,TAGLN3,ATP2B2,TNIK,ACSL6,NUMA1,OMG,USP2,PRMT8,CABP1,PACSIN1,OSBPL3,ATRNL1,PTAFR,RABGAP1L,DLG2,NUP214" Drug 3421_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACTN2,ARID1A,SYBU,MSR1,PDE8B,ASPH,ALDH4A1,WDTC1,NDUFA5,INKA2,BTRC,CAMK2G,TGFBR3,CDH8,PTGDR2,PDE3B,PTPRE,RGS10" Drug 6612_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACHE,SYNDIG1,ACTN2,SLC1A7,ASTN1,CPLX2,PHLDB1,HAP1,PADI2,DCLK1,ZMYND8,CHRNB2,SLC22A6,CP,SMG7,DTNA,EFNA3,ROM1" Drug 2966_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "PLA2G6,FHL1,CDC42BPA,SLC1A7,SLN,GAD2,INKA2,NRGN,PADI2,ZFYVE9,UBTF,CTNND2,EDRF1,PTAFR,SMG7,RET,ROM1,LRRC23" Drug 3306_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ADCY2,MOBP,CDC42BPA,APBA2,APC,SHANK2,TAGLN3,WSCD1,GPM6A,ZEB1,CAMK2G,NEURL1,ASIC3,MAPK10,NOS1AP,PLPPR1,PTHLH,NAV2" Drug 3764_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "KLRC4,C1orf61,BCAS1,ASTN1,ATP1A2,DKK3,ALDH1L1,GNG4,NUMA1,PDE2A,KIAA1549L,SULT4A1,FEZ1,PSD,KCNMA1,ATN1,DTNA,LRRC23" Drug 2251_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "KIAA1109,CDC42BPA,ANK1,SLC2A5,BRINP2,MLC1,GLS,WSCD1,PSD3,ZFYVE9,SDC3,PRDM2,KCNC1,KCNQ2,RAB3IL1,RAD52,ATN1,LMO1" Drug 4633_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ARID1A,FOXG1,MADD,PDE8B,SLN,ASTN1,CADM3,EMC1,GART,NEUROD1,KAZN,PCDH9,CABP1,SF1,KIAA0513,GON4L,KIF2A,ST8SIA3" Drug 6618_UP Protoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ABAT,APC2,ARID1A,ADORA1,KIAA1109,FGF1,GAS7,KIF21B,GAD2,ALDH1L1,PHLDB1,GPM6A,HAP1,CHRNB2,PROX1,PLPPR4,DTNA,ELAVL3" Drug 2497_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,ADCY2,CDC42BPA,PKP4,BCAN,AQP4,CGREF1,ALDH1L1,SLCO1C1,GPM6A,NPPA,ATP13A2,PCSK2,POU3F2,CTNND2,KIAA0513,DTNA,RASGRP2" Drug 2359_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,CDHR1,PLA2G6,FOXG1,DNAH17,SNAP25,DKK3,KIF1B,FAM168A,VAMP1,CAMK2A,CDC42,MAGI1,STMN4,PTPRO,RAP1GAP,ST8SIA3,SIDT2" Drug 4065_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,MOBP,AQP4,SLC1A7,ASTN1,ATP1A3,ACSBG1,ADGRL3,OPCML,ARHGAP22,TENM4,ARHGEF4,STMN4,RAB3IL1,ABCC9,ST8SIA3,RGS7,RGS10" Drug 3809_UP Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAG,MOBP,GAS7,SLC1A2,SLC2A5,SLC14A1,SLCO1A2,SLN,ADGRB2,ALDH1L1,INKA2,ACSBG1,PADI2,CADM1,PLCH2,RIMS3,PTCH1,SMG7" Drug 3032_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACTN2,APBA2,AQP4,ASTN1,MYBPC1,ALDH1L1,ROBO3,GNG4,MYRF,BRSK2,GRIA4,ADAMTS8,OMG,OPCML,SEZ6L,HPSE2,ZBTB16,SLC6A15" Drug 3532_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "RYR1,ADORA3,SEMA6A,MOBP,APBA2,SYBU,TAGLN3,SLN,ALDH4A1,RND1,PCSK2,SULT4A1,CRMP1,SDC3,IGSF1,PTAFR,PTHLH,NUP214" Drug 2297_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,ADCY2,SLC14A1,INKA2,GLS,POPDC3,PSD3,INA,SLC22A6,FADS2,TENM4,ITIH2,KCND3,DSCAM,RASGRF1,ST8SIA3,TTLL7,ELAVL3" Drug 7450_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,PAQR6,CLIP1,TUBB4A,KIAA1109,PLA2G6,SHANK2,ZCCHC24,GAD2,GLS,CACNA1A,PRUNE2,PAX6,PDE4B,SERPINE2,PIK3CD,TMCC2,RAD52" Drug 5471_UP Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MDM4,AGT,SLC2A5,PKNOX2,ASPH,ALDH4A1,WDTC1,GNAS,NUMA1,FLRT1,SULT4A1,VAV2,CNTN1,MICAL1,GON4L,JAKMIP2,HP1BP3,STMN4" Drug 3121_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ASIC1,ADORA1,MOBP,AMPH,APBA2,NTNG1,SORBS1,ALDH4A1,ATP2B2,PALLD,ZSWIM8,ALDH1L1,WSCD1,CACNB2,DUSP26,JAKMIP2,KCNK1,PID1" Drug 4427_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACTN2,ASIC4,BRINP2,ATM,NCDN,RND1,KLHL4,HAP1,PADI2,PCDH9,TPM3,PDE2A,CA14,PKN2,EDRF1,RIMS3,PTCH1,PLPPR4" Drug 2822_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "ACTN2,SFPQ,RASA3,APBA2,PDE8B,ASPH,ATM,EMC1,NPAS3,RND1,FAM168A,SEMA4A,PDE3B,ZMYND8,CCSER2,NOS1AP,DTNA,VWA5A" Drug 3206_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "MAPT,CEND1,NDRG2,GAS7,SORBS1,AQP4,PKNOX2,GPR153,SNAP25,MYT1L,KIF21B,KCNK10,PCDH8,PMP2,ARHGEF4,NOS1AP,PTPRO,EFNA3" Drug 6484_UP Urosiol [128-13-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "RYR1,ASPH,SNAP25,CCDC181,CADM3,NDUFA5,ACSBG1,NHLH1,ASTN2,CAMK2G,PSD3,NSD2,TENM4,PHYHIP,PTAFR,HP1BP3,RAB3IL1,NUP214" Drug 2402_DN Chenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "FOXRED2,FHL1,ANK2,ITSN1,GAS7,SLC1A7,GAD2,COLGALT2,ALDH1L1,ADGRL3,NUCB1,GON4L,PTAFR,RABGAP1L,RAB3IL1,RALGDS,RGS10,ARHGEF10L" Drug 6040_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.03E-03 1.00E+00 2.16E-02 2.37E-01 18 199 "CDHR1,GRAMD1B,KIAA1109,ASIC4,SELL,ANK1,RPH3A,SLC1A7,PKNOX2,WDTC1,NPPA,GRIA1,KCNK10,DUSP26,MICAL1,POU3F4,PLCH2,MAPK8" Drug CID000004402 AC1Q4Y39 Stitch 1.03E-03 1.00E+00 2.16E-02 2.37E-01 9 65 "ADAR,F3,ADARB2,ADORA1,ADORA3,MLC1,HRH3,CHRM1,PTPA" Drug ctd:C011559 tributyltin CTD 1.06E-03 1.00E+00 2.20E-02 2.42E-01 33 466 "TTYH1,RIMKLA,MAPT,RXRG,AGT,SOX6,SORBS1,JAKMIP3,LRRC4C,DKK3,SOX5,NDUFA5,GFAP,SYT4,NODAL,NRDC,CAMK2G,GRIA1,GRIA2,GRIA4,GRIN1,TF,CCKBR,LEFTY2,TJP1,PC,PTGDR2,CA14,JAM2,MAPK8,KCNH1,L1CAM,ABCC9" Drug CID005126051 AC1NNRU4 Stitch 1.06E-03 1.00E+00 2.21E-02 2.42E-01 7 41 "ADORA1,FOXM1,SHANK2,GRIA1,GRIA2,GRIA4,GRM3" Drug ctd:D002330 Carmustine CTD 1.06E-03 1.00E+00 2.21E-02 2.43E-01 34 485 "APC2,EXTL1,MEG3,MDM4,F3,PLEKHG5,AGT,SFPQ,ANK2,APC,ST8SIA1,MSR1,PKNOX2,SLC14A1,CGREF1,SLCO1A2,ATP1A3,FYN,NEK6,ADAM15,GFAP,POPDC3,NKX2-2,CHRM4,CADM1,PIK3CD,MED1,SF1,MAPK10,MASP1,ELMO1,KCNA4,RGR,PHC2" Drug 6838_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "RYR1,PLA2G6,MOBP,CDC42BPA,ANK1,MSR1,SLC14A1,KAZN,GNG3,CACNA1A,WSCD1,GUCY1A2,TNS1,PIK3CD,RGS6,DNAJC6,KCND3,TMCC2" Drug 5523_UP Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "ACTN2,FHL1,APBA2,PKNOX2,DNAH17,DDX25,GNG4,OMG,PDE4B,ADGRG1,CNTN1,MICAL1,PACSIN1,TOX,ITIH2,ATG16L1,FAM13C,VWA5A" Drug 4377_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "TTYH1,ADORA1,TUBB4A,KIAA1109,FGF1,ANK1,DLL3,ATP1A2,NFASC,RND1,OMG,NEURL1,SEZ6L,PIK3CD,OSBPL3,CNIH3,RAD52,ELAVL3" Drug 4820_UP Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "SYNDIG1,RYR1,SLC2A5,CCDC88A,MYH7,ARPP21,COLGALT2,FGF17,GNAS,NPPA,CACNB2,OLR1,INA,CDH8,PIK3CD,ITIH2,NUP214,EPB41L1" Drug 4202_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "AMPH,APC,NTNG1,SLC14A1,TNIK,B4GALNT1,HAP1,PADI2,PTGDR2,NRXN1,CAMKV,SPATA6,PKN2,MAGI2,KCND3,RAD52,EFNA3,RPRD1A" Drug 5497_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "SYNDIG1,NDRG2,FHL1,SELL,SLC2A5,MSR1,SLN,LMO3,SEMA4A,GRIN1,CDC42,PDE2A,VAV2,MICAL2,EDRF1,PTPRO,ATG16L1,CRTAC1" Drug 5991_UP Phenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "DPF1,EMID1,PLA2G6,FHL1,MOBP,SYBU,ZCCHC24,EMC1,ALDH1L1,PDE3B,GPR37L1,ZFYVE9,NECAB2,NOS1AP,KCNJ4,TMCC2,DTNA,RASGRP2" Drug 3878_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "DPF1,EMID1,NDRG2,FGF1,RPH3A,PDE8B,ASPH,CADM3,GNG3,PAH,TNS1,PDE1C,CRMP1,TENM4,GON4L,PTAFR,TTLL7,LMO1" Drug 2919_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "CDHR1,EMID1,ALDH4A1,ATP2B2,GPR162,VAMP1,BTRC,CACNB2,GRIN1,OPCML,RBFOX2,SULT4A1,CABP1,CTNND2,PHYHIP,NKAIN1,RAB3IL1,RAVER2" Drug 3019_UP Furazolidone [67-45-8]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "ABAT,MAPT,RYR1,CDC42BPA,ANK3,ASPH,ATP1A2,PALLD,VAMP1,CDH10,SEZ6L,LILRA4,GPR37L1,NRXN2,RGS6,IGSF1,KCNC1,ST8SIA3" Drug 5432_UP Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "ASIC1,ACTN2,FGF1,AMPH,WDTC1,ALDH1L1,POPDC3,ROBO3,PRUNE2,NPPA,OPCML,CELF3,SCRG1,ZFYVE9,PTPRO,RAB3IL1,RAD52,DTNA" Drug 3030_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "ADORA1,ASIC4,BCAN,AQP4,CCDC181,MYBPC1,TNIK,GAD2,WWC1,KCNK10,REPS2,VAV2,PMEPA1,PLPPR4,KCNH1,SEC61A2,EFNA3,OLIG2" Drug 2997_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "RYR1,FOXG1,AMPH,SORBS1,PKNOX2,SCG3,B3GAT1,ATP1A3,GAD2,NCAM1,ALDH1L1,AJAP1,GPM6B,GUCY1A2,HPSE2,CCSER2,TENM4,PMEPA1" Drug 5601_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "SYNDIG1,NDRG2,RYR1,AGT,APC,SYBU,CCDC181,NPAS3,NCAM1,KAZN,ADGRL3,ZEB1,GUCY1A2,PDE1C,HPSE2,ZFYVE9,KCND3,FAM13C" Drug 5744_UP Calycanthine [595-05-1]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "APC2,APC,SORBS1,BCAS1,TAGLN3,EMC1,COLGALT2,ALDH1L1,RND1,HAP1,INA,CHI3L2,KIAA1549L,COL9A2,PRDM2,RABGAP1L,VWA5A,RCAN2" Drug 4227_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "NLGN4X,LRRTM4,MOBP,PKP4,TNIK,NFASC,GPM6B,ATF7,HAP1,GRIK3,MAGI1,CHI3L2,ASIC3,RIMS3,RABGAP1L,DTNA,ABCC9,OLIG2" Drug 1368_UP Diazoxide [364-98-7]; Up 200; 17.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "PAQR6,CLIP1,PKP4,EIF4G3,WDTC1,ZSWIM8,KIF1B,GNAS,WWC1,TCF7L2,OMG,SPX,CELF3,RBFOX2,CADM1,C1orf109,RAB3IL1,DTNA" Drug 2278_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "SYNDIG1,ASIC4,AMPH,PKNOX2,SLCO1A2,GPM6A,GPM6B,NPPA,TGFBR3,PTGDR2,PDE4B,ZFYVE9,PACSIN1,PTHLH,TMCC2,KCNK2,RAD52,FAM13C" Drug 4588_UP Vitexin [3681-93-4]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "DPF1,FOXRED2,AGT,GAD2,NCAM1,KAZN,CDK5R2,GPR17,P2RX7,CDH8,ADGRG1,NRXN2,VCAN,CNIH3,PLPPR4,RABGAP1L,ATN1,DTNA" Drug 2633_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "ASIC1,MAPT,TUBB4A,AGT,C1orf61,ANK1,APBA2,ZNF365,MSR1,CPLX2,RND1,PSD3,OMG,PIK3CD,GON4L,ATG16L1,SIDT2,ELAVL3" Drug 3640_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "NDRG2,FABP7,ANK2,ASTN1,ATP2B2,RND1,NUMA1,GPR37L1,CA14,CHI3L2,PIK3CD,NMT2,ELMO1,PRDM2,RABGAP1L,TTLL7,RAVER2,RASGRP2" Drug 4080_UP Cefadroxil [50370-12-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-03 1.00E+00 2.25E-02 2.46E-01 18 200 "RTN1,KIAA1109,RASA3,BRINP2,ATP1A2,ATP2B2,MYT1L,PHLDB1,GRIK4,MAGI1,PDE2A,CADM1,SPATA6,MICAL2,CTNND2,MAPK10,RAB3IL1,DTNA" Drug CID000005618 U46619 Stitch 1.10E-03 1.00E+00 2.25E-02 2.47E-01 23 285 "ACER3,RTKN,ADCY2,RYR1,AGT,ACTL6B,NODAL,CACNA1A,CACNA1E,CACNB2,LEFTY2,GUCY1A2,PTGDR2,PDE1A,PDE1C,PDE3B,CHRM1,P2RY12,PRKCG,PKN2,PRKCZ,PTAFR,CACNG7" Drug CID000040461 isoarecoline Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "ACHE,CCDC88A,CHRM1" Drug CID000004047 mefruside Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "PTPN5,SLC22A6,HPR" Drug CID000214788 Ro 44 Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "F3,RBFOX2,CNTN1" Drug CID009549889 3-IN Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "RYR1,MOG,UBTF" Drug ctd:C010192 9-(2-hydroxy-3-nonyl)adenine CTD 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "PDE8B,NPPA,PDE2A" Drug CID000133976 alpha-sialylcholesterol Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "FGF1,CACNA1A,CACNA1E" Drug ctd:D005703 Gallamine Triethiodide CTD 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "ACHE,CHRM1,CHRM4" Drug CID010948590 CID10948590 Stitch 1.14E-03 1.00E+00 2.34E-02 2.57E-01 3 6 "KCNA1,KCNA2,KCNA6" Drug CID000003845 kynurenic acid Stitch 1.15E-03 1.00E+00 2.34E-02 2.57E-01 13 122 "ABAT,FGF1,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,CHRNB2,SULT4A1,ETNPPL" Drug CID000001233 ibotenic acid Stitch 1.15E-03 1.00E+00 2.34E-02 2.57E-01 13 122 "ACHE,GAD2,GFAP,GRIA1,GRIA2,GRIA4,GRID1,GRIK3,GRIK4,GRM3,PDYN,CHRM1,EEF1A2" Drug ctd:D020106 Acrylamide CTD 1.16E-03 1.00E+00 2.36E-02 2.59E-01 18 201 "ACHE,MBP,RYR1,SLC14A1,ATM,MYBPC1,CPLX2,NCAM1,GFAP,ARHGEF7,GLS,GRIN1,GUCY1A1,TJP1,MAPK8,ITGAV,KCNQ2,ABI1" Drug CID000161930 icilin Stitch 1.17E-03 1.00E+00 2.39E-02 2.63E-01 5 21 "ASIC1,PLA2G6,FOLH1,SLC1A2,CHGA" Drug CID000126897 AC1L2R46 Stitch 1.17E-03 1.00E+00 2.39E-02 2.63E-01 5 21 "MAG,MOBP,MOG,CCDC88A,OMG" Drug 2680_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.18E-03 1.00E+00 2.41E-02 2.64E-01 17 185 "TUBB4A,TESK2,PALLD,ZSWIM8,NCAM1,RGL1,RND1,GLS,CAMSAP2,GOLGB1,INA,PCDH9,DZIP3,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug 2457_UP Hexetidine [141-94-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.18E-03 1.00E+00 2.41E-02 2.64E-01 17 185 "ACTN2,FHL1,DNAH17,CCDC181,BCL2L2,GNG4,CAMSAP2,OLR1,USP2,ZMYND8,ZFYVE9,VCAN,MAPK8,PLPPR1,KCNMA1,RAD52,SEC61A2" Drug 5906_UP valinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.18E-03 1.00E+00 2.41E-02 2.64E-01 17 185 "ARID1A,RYR1,SEMA6A,FHL1,ANK2,PPM1E,RPH3A,SLC6A9,KIF21B,BTRC,WSCD1,PSD3,PTGDR2,FEZ1,NAV2,RAD52,DTNA" Drug CID000060703 eliprodil Stitch 1.22E-03 1.00E+00 2.48E-02 2.71E-01 6 31 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000108099 NPC 12626 Stitch 1.22E-03 1.00E+00 2.48E-02 2.71E-01 6 31 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID015947913 mu v Stitch 1.22E-03 1.00E+00 2.48E-02 2.71E-01 6 31 "NASP,NEU4,ZBTB16,SIRPA,GNE,ROM1" Drug CID000006212 chloroform Stitch 1.22E-03 1.00E+00 2.48E-02 2.71E-01 14 138 "MBP,PDZD4,LRRC4C,NKX6-2,NAP1L2,GPR162,ACSBG1,KCNK10,OPALIN,PMP2,PRKCG,PKN2,PRKCZ,KCNK2" Drug CID000007371 benzenesulfonate Stitch 1.23E-03 1.00E+00 2.49E-02 2.73E-01 7 42 "ANK1,GRIK2,HMGB1,PRKCG,PKN2,PRKCZ,RAB3IL1" Drug CID005366189 AC1NSN3X Stitch 1.24E-03 1.00E+00 2.52E-02 2.76E-01 8 54 "ASIC1,KLRC4,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug CID000003184 E 4031 Stitch 1.24E-03 1.00E+00 2.52E-02 2.76E-01 8 54 "KCNA1,KCNA2,KCNA6,KCNC1,KCND3,KCNH1,KCNMA1,KCNQ2" Drug CID000447083 S)-ACPA Stitch 1.24E-03 1.00E+00 2.52E-02 2.76E-01 8 54 "ADORA3,GRIA1,GRIA2,GRIA4,GRM3,PMP2,SIRPA,PCDH15" Drug 3902_DN Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.25E-03 1.00E+00 2.54E-02 2.78E-01 17 186 "ADD3,CDC7,GAS7,SLC1A7,ATM,WDTC1,TCF7L2,GPR19,NUMA1,PDE3B,DZIP3,MAPK8,EDRF1,BRINP3,PTHLH,ATN1,DSCAM" Drug 849_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.27E-03 1.00E+00 2.56E-02 2.81E-01 16 170 "MAG,SERPINA3,MBP,CLIP1,SYBU,PHLDB1,AJAP1,KAZN,PADI2,PFKFB3,MICAL2,KLK6,NAV2,RAP1GAP,SSPN,EPB41L1" Drug 5258_UP Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-03 1.00E+00 2.68E-02 2.94E-01 17 187 "HPCAL4,APBA2,DOCK10,SORBS1,ASPH,GAD2,ALDH1L1,RND1,ZEB1,PCDH9,CRMP1,SDC3,PTPRD,RAB3IL1,ATN1,TTLL7,SIDT2" Drug CID000004401 N6-cyclopentyl-9-methyladenine Stitch 1.33E-03 1.00E+00 2.68E-02 2.94E-01 4 13 "ADAR,ADARB2,ADORA1,ADORA3" Drug CID000006367 acetyl chloride Stitch 1.33E-03 1.00E+00 2.68E-02 2.94E-01 4 13 "ACLY,F3,API5,NAP1L2" Drug CID000164437 HENECA Stitch 1.33E-03 1.00E+00 2.68E-02 2.94E-01 4 13 "ADARB2,ADORA1,ADORA3,NPPA" Drug ctd:D004026 Dieldrin CTD 1.35E-03 1.00E+00 2.72E-02 2.98E-01 70 1221 "SERPINA3,MAPT,ACLY,MBP,MDM4,CDC7,HOGA1,TESK2,AGT,KIAA1109,FGF1,SOX6,ANK1,APBB1,API5,USP16,MIER1,ARFGAP2,BRINP2,SNAP25,ATM,FYN,SON,GAD2,NASP,ERBIN,GFAP,GFRA1,FGF17,SLCO1C1,ABCC8,GPM6B,VWC2,GPR17,CAMK2A,CAMK2G,GRIA1,GRIA2,GRID1,GRIK3,GRIN1,CCKBR,P2RX7,TJP1,AIFM1,PC,DCLK1,LGI1,CHRM1,CHRM4,BEST1,NSD2,CNRIP1,SF1,MAPK10,ZBTB16,TOMM20,LRRTM3,RGMA,PARD6A,PTPRO,PYGM,NKAIN1,RTN4,NUP214,RET,ST8SIA3,SFXN5,LMO1,VWA5A" Drug CID000001915 "8-bromoguanosine 3',5'-cyclic monophosphate" Stitch 1.39E-03 1.00E+00 2.81E-02 3.08E-01 24 308 "RYR1,ADD3,AGT,ACTL6B,MLC1,CACNA1A,CACNA1E,NPPA,CACNB2,NUMA1,GUCY1A2,GUCY1A1,KCNK10,PDE1C,PDE2A,CHRM1,PHKG1,PIK3CD,PTPA,PRKACB,PRKCG,KCNC1,KCNMA1,CACNG7" Drug 2208_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.41E-03 1.00E+00 2.83E-02 3.11E-01 17 188 "WLS,NDRG2,CDC42BPA,DLL3,PALLD,TNIK,ZSWIM8,NCAM1,ATP13A2,NEURL1,RBFOX2,BEST1,EDRF1,RIMS3,DNAJC6,STMN4,CRTAC1" Drug 4616_UP Bisacodyl [603-50-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 2.83E-02 3.11E-01 17 188 "EMID1,RTN1,SEMA6C,AMPH,MSR1,B3GALT2,PHLDB1,GNG4,CDH8,CAMKV,VAV2,CRMP1,KCNC1,KCNJ4,DTNA,ABCC9,EN2" Drug 4209_UP Zardaverine [101975-10-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.41E-03 1.00E+00 2.83E-02 3.11E-01 17 188 "EMID1,GRAMD1B,ST8SIA1,ASCL1,MYH7,NPAS3,SPART,SEZ6L,PDE4B,HPSE2,PKN2,CTNND2,PTHLH,SRGAP3,ARNT2,RASGRF1,ST8SIA3" Drug CID000007410 acetophenone Stitch 1.45E-03 1.00E+00 2.91E-02 3.19E-01 6 32 "APC,ADHFE1,ANKS1B,PTCH1,KCNH1,RCAN2" Drug CID000152917 imidazole-4-carboxamide Stitch 1.45E-03 1.00E+00 2.91E-02 3.19E-01 6 32 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000004938 propentofylline Stitch 1.45E-03 1.00E+00 2.91E-02 3.19E-01 6 32 "ADORA1,ADORA3,SLC1A2,GFAP,DNM2,EPB41" Drug CID000656468 AC1LCV0V Stitch 1.45E-03 1.00E+00 2.91E-02 3.19E-01 6 32 "ADAR,ADARB2,AHCYL1,RBFOX2,TUB,PYGM" Drug ctd:C041786 palm oil CTD 1.48E-03 1.00E+00 2.98E-02 3.26E-01 94 1742 "MAG,EPS8,SERPINA3,ABAT,ACLY,MBP,EXTL1,ACTN2,ADGRV1,LDLRAD3,SLC25A25,F3,CLIP1,FCGR1A,FGF1,PLA2G6,C1QTNF4,FHL1,RASA3,CCDC80,GPAM,SLC8A3,DACH2,GPR153,SLN,ALDH4A1,DKK3,B3GALT2,MYH7,FXYD6,ALDH1L1,SMOC1,DCAF5,ADHFE1,ARHGEF7,C1QC,SEMA4A,DDHD2,CAMTA1,KLHL4,TBX15,GPM6A,ACSL6,TF,TMEM25,FBXL16,TMEM9,TJP1,PC,LGI1,TPM4,PDE1A,PDE4B,FNDC5,ACOT7,LRTM2,PFKFB3,MS4A7,DUSP26,SERPINE2,CADM1,NEGR1,CCSER2,FADS2,FTO,PMP2,PRRX1,MFSD4A,CP,ETNPPL,SF1,CRLS1,PRKAB2,ZBTB16,WBP1L,ZNF385B,PMEPA1,PTHLH,MED24,PTPRE,KCNJ11,CCDC3,KCNMA1,OLIG1,C12orf4,RFX4,RGS10,ARHGEF10L,SFXN5,LMO1,FGFBP3,LPAR6,BSCL2,TMEM100" Drug 4464_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-03 1.00E+00 2.99E-02 3.28E-01 17 189 "ASIC1,ACTN2,TUBB4A,APBB1,APC,FYN,ADGRB2,KLHL4,TGFBR3,TNS1,VCAN,EDRF1,FAM131B,RIMS3,PTCH1,MAGI2,LRRC23" Drug CID000003925 QX-314 Stitch 1.51E-03 1.00E+00 3.01E-02 3.30E-01 10 82 "SCN4B,SCN3B,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,GRM3,ASIC3,CHRM1" Drug CID000447988 AC1L9LGY Stitch 1.51E-03 1.00E+00 3.01E-02 3.30E-01 10 82 "FGF1,SOX1,NCAM1,GFRA1,NEUROD1,TJP1,RET,RLBP1,OLIG2,RPE65" Drug 1672_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.52E-03 1.00E+00 3.04E-02 3.33E-01 16 173 "DPF1,ADD3,SEMA6A,PPM1E,ZNF365,FYN,ZCCHC24,RGL1,ACSBG1,PCDH9,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3" Drug 7105_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.52E-03 1.00E+00 3.04E-02 3.33E-01 16 173 "ABAT,TESK2,SH3GL2,SORBS1,FYN,RGL1,VAMP1,NRGN,REPS2,PCDH9,PIK3CD,DNAJC12,RIMS3,PTCH1,PLPPR4,EFNA3" Drug CID000003209 AC1L1FF5 Stitch 1.53E-03 1.00E+00 3.05E-02 3.34E-01 15 157 "F3,FABP7,AGT,SCN4B,GPAM,BCO1,FYN,SCN3B,NAP1L2,ASIC3,PLEKHB1,CPT1C,FADS2,MAPK8,KCNMA1" Drug CID000001310 "1-aminocyclopentane-1,3-dicarboxylate" Stitch 1.55E-03 1.00E+00 3.09E-02 3.38E-01 12 111 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3,APC,GRIK3,GRIK4,GRM3,OMG,CHRM1,PRKCG" Drug ctd:C025340 manganese chloride CTD 1.55E-03 1.00E+00 3.09E-02 3.39E-01 32 458 "MAPT,ACHE,MBP,DSCAML1,FCGR1A,FHL1,APC,SLC1A2,DACH2,ATM,ATP2B2,SCN3B,MYT1L,STOX1,GFAP,NPPA,GRIK3,GRIN1,LEFTY2,TIE1,RGS6,ARHGEF4,MAPK8,MASP1,ITGAV,ITIH2,LRP8,RTN4,RET,SFXN5,ABI2,SLC4A10" Drug 2700_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.58E-03 1.00E+00 3.14E-02 3.45E-01 17 190 "MAPT,MOBP,ANK3,DNAH17,ASPH,B3GALT2,NCAM1,RGL1,BRSK2,USP2,LILRA4,DZIP3,IGSF1,NOS1AP,RIMS3,KCNC1,KCND3" Drug 4500_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-03 1.00E+00 3.14E-02 3.45E-01 17 190 "PLA2G6,ASIC4,BCAS1,RND1,CDC42,PTGDR2,PDE1C,PDE3B,PIK3CD,SULT4A1,CABP1,MICAL2,CHD5,PTPRD,KCND3,RASGRF1,RGS7" Drug 4421_DN Lidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.58E-03 1.00E+00 3.14E-02 3.45E-01 17 190 "MOBP,APC,PKNOX2,CCDC88A,GPR153,ATM,ALDH1L1,NEUROD1,ABCC8,ROBO3,HAP1,ZMYND8,ADGRG1,VAV2,PLPPR1,ITIH2,RAD52" Drug 5579_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.58E-03 1.00E+00 3.14E-02 3.45E-01 17 190 "DPF1,SYNDIG1,DOCK10,ARHGAP5,CCDC88A,DNAH17,SLN,FYN,TNIK,NAP1L2,GNAS,ROBO3,WSCD1,ZEB1,MICAL2,KLK6,DTNA" Drug 4314_UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.58E-03 1.00E+00 3.14E-02 3.45E-01 17 190 "FABP7,FGR,MOBP,SLC1A7,ADAM15,NCDN,KLHL4,GPM6B,NUMA1,NEURL1,ADGRG1,VAV2,IFFO1,NAV2,RAB3IL1,RAD52,ABCC9" Drug CID000008035 "2,5-hexanedione" Stitch 1.58E-03 1.00E+00 3.14E-02 3.45E-01 8 56 "ACHE,TUBB4A,GFAP,ADHFE1,TUBB2B,KCNA4,KCNH1,NUP214" Drug 2084_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.62E-03 1.00E+00 3.21E-02 3.52E-01 16 174 "ABAT,TESK2,SYBU,ALDH4A1,FYN,TNIK,RGL1,PSD3,TGFBR3,PCDH9,NMT2,DNAJC12,PTCH1,DNAJC6,PLPPR4,EFNA3" Drug CID000002433 AC1L1DNZ Stitch 1.62E-03 1.00E+00 3.22E-02 3.54E-01 7 44 "SCN4B,GABBR1,SCN3B,GJB1,ASIC3,KCNA1,KCNA2" Drug DB01080 Vigabatrin Drug Bank 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ABAT,GABBR1" Drug CID003016673 4-hydroxypyridine-3-sulfonic acid Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "F3,CNTN1" Drug ctd:C075004 PD 81723 CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ADORA1,ADORA3" Drug CID011845779 X0337 Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "MBP,PMP2" Drug CID000034254 "2,6-dichlorostyrene" Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "WLS,PMP2" Drug CID006432872 AC1O5F3I Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "INA,RET" Drug ctd:C111998 sampatrilat CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "AGT,NPPA" Drug ctd:C438612 VUF 5455 CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ADORA1,ADORA3" Drug CID000146303 AC1L3SY5 Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ABAT,PTCH1" Drug CID005461043 chacotriose Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ACHE,ACLY" Drug ctd:C087255 mitiglinide CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ABCC8,KCNJ11" Drug CID000011204 acetyl fluoride Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ACHE,PMP2" Drug CID000040153 pT-T-A Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ACLY,F3" Drug ctd:C023366 4-bromohomoibotenic acid CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "GRIA1,GRIA2" Drug CID000360199 petrosamine Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ACHE,F3" Drug CID000172854 LICAM(S Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "DLL3,TF" Drug ctd:C570534 "7-chloro-3-(1-hydroxy-2-propyl)amino-4H-1,2,4-benzothiadiazine 1,1-dioxide" CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ABCC8,KCNJ11" Drug ctd:C008425 S-methylcysteine CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "MSRA,PAH" Drug DB02999 Quisqualate Drug Bank 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "GRIA2,GRIK2" Drug CID000151898 AC1L479N Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ABAT,PTCH1" Drug ctd:C419146 "2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate" CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "ADORA3,NPPA" Drug ctd:C474829 2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid CTD 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "GRIA1,GRIA2" Drug CID000159334 Phleomycin E Stitch 1.65E-03 1.00E+00 3.22E-02 3.54E-01 2 2 "NUCB1,KCNMA1" Drug CID003899541 DNQX Stitch 1.65E-03 1.00E+00 3.23E-02 3.54E-01 10 83 "GFAP,NUCB1,GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,PDYN,MAPK10" Drug CID005356750 Evans blue dye Stitch 1.66E-03 1.00E+00 3.24E-02 3.55E-01 13 127 "SCNN1D,AQP4,B3GAT1,GFAP,GNAS,NPPA,GRIA1,P2RX7,HRH3,PDE2A,NTSR2,P2RY12,SLC17A6" Drug CID000018879 rhombic Stitch 1.67E-03 1.00E+00 3.26E-02 3.58E-01 12 112 "ADGRV1,ASCL1,DLL3,NHLH1,ROBO3,CNTN2,ZEB1,NRGN,PAH,PDE1C,EN2,OLIG2" Drug 2137_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.67E-03 1.00E+00 3.26E-02 3.58E-01 17 191 "PALLD,ZCCHC24,NCAM1,RGL1,CAMSAP2,BTRC,GPR19,NRGN,NUMA1,PSD3,ATP13A2,PADI2,PCDH9,RIMS3,DNAJC6,SV2A,TMEM255A" Drug 3830_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 3.26E-02 3.58E-01 17 191 "ADCY2,C1orf61,SELL,ASPH,TNIK,GPM6A,CACNB2,NEURL1,PDE3B,ZFYVE9,FADS2,VAV2,PACSIN1,PTAFR,KCNMA1,DTNA,EPB41" Drug CID000003182 dyphylline Stitch 1.71E-03 1.00E+00 3.33E-02 3.65E-01 6 33 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B" Drug CID000002071 "1-aminoindan-1,5-dicarboxylic acid" Stitch 1.71E-03 1.00E+00 3.33E-02 3.65E-01 6 33 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000028516 mellein Stitch 1.71E-03 1.00E+00 3.33E-02 3.65E-01 6 33 "AGT,SMARCE1,B3GAT1,NUCB1,KCNH1,PCDH15" Drug ctd:D006160 Guanosine Triphosphate CTD 1.71E-03 1.00E+00 3.33E-02 3.65E-01 6 33 "AGT,GNAS,GUCY1A2,GUCY1A1,CDC42,HRH3" Drug CID000010595 lithocholyltaurine Stitch 1.71E-03 1.00E+00 3.33E-02 3.65E-01 16 175 "ABAT,FOXG1,SLCO1A2,GFAP,CACNA1A,PAH,HPR,PACSIN1,PRKCG,PKN2,PRKCZ,CA10,PRTFDC1,PYGM,ATN1,EN2" Drug 1161_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.71E-03 1.00E+00 3.33E-02 3.65E-01 16 175 "ADD3,TESK2,PALLD,ZCCHC24,ZSWIM8,NCAM1,RGL1,RND1,CAMSAP2,PADI2,NMT2,CCSER2,KIAA0513,RIMS3,DNAJC6,EFNA3" Drug ctd:D014415 Tunicamycin CTD 1.75E-03 1.00E+00 3.39E-02 3.72E-01 86 1577 "DPF1,ACER3,MDM4,RTN1,CDC7,TUBB4A,AGT,C1orf61,FOXM1,SFPQ,ANK2,PPM1E,CLSTN1,SLC6A9,YPEL4,CGREF1,PDE8B,TAGLN3,DLL3,RCOR3,TMEM108,SNAP25,PHYHIPL,NEK6,NAP1L2,FXYD6,LMO3,BCL2L2,NDUFA5,ERBIN,RCOR2,GLS,ZNF638,OS9,GNAS,GNG4,PSRC1,GPM6B,NPPA,CACNB2,NUCB1,AKNA,VWCE,MFSD2A,INA,GUCY1A1,PCDH9,CDH10,PDE4B,ZMYND8,ACOT7,CHGA,PFKFB3,DUSP26,SERPINE2,CADM1,CPT1C,NMT2,DNAJC12,CABP1,SLC25A27,BEST1,CHD1L,MED1,PPP3CB,KCNT2,FEZ2,VCAN,CTNND2,MAPK8,RIMS3,CA10,LRP8,AK5,KCNK1,RAB3IL1,DSCAM,CAMK1G,RET,EEF1A2,SFXN5,SIDT2,RBM12,CBLN2,TMEM100,SEZ6" Drug CID000003758 IBMX Stitch 1.76E-03 1.00E+00 3.41E-02 3.74E-01 27 368 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3,AGT,FGF1,FOXM1,MIER1,PDE8B,GFAP,GNAS,NPPA,CACNB2,AZIN2,GUCY1A2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CHRM1,VCAN,PRKACB,PRKCG,PTHLH,PYGM" Drug ctd:D002713 Chlorine CTD 1.76E-03 1.00E+00 3.41E-02 3.74E-01 27 368 "ADCY2,ADORA3,FGR,HPCAL4,AMPH,APC,SLC1A6,SLC6A9,SNAP25,GABBR1,NELL1,SYT4,GNAS,CACNA1A,GRIN1,CCKBR,NTSR2,ACOT7,NRXN1,NRXN2,SIRPA,PTAFR,KCNA4,KCNJ4,DPP6,RALGDS,SLC6A15" Drug CID000004932 propafenone Stitch 1.77E-03 1.00E+00 3.42E-02 3.75E-01 11 98 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,KCNK10,ASIC3,PNKD,KCNA2,KCNA4" Drug 3179_UP Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "LRRTM4,HPCAL4,ANK1,DLL3,ATP2B2,RGL1,SPX,CDC42,DCLK1,SEZ6L,PDE3B,RGS6,MICAL2,KCNJ4,TMCC2,KCNMA1,DTNA" Drug 7489_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "EMID1,MBP,KIAA1109,FHL1,INKA2,RGL1,GNAS,EML4,NEURL1,PTGDR2,PDE3B,ADGRG1,CRMP1,RGS6,EDRF1,HP1BP3,VWA5A" Drug 6684_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "MDM4,TUBB4A,GAS7,AQP4,PKNOX2,SLC6A9,ATP1A3,ATP2B2,TNIK,ADGRB2,NCAM1,TNS1,MICAL2,VCAN,STMN4,KCNC1,EFNA3" Drug 2183_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "ADORA3,FOXG1,CDC42BPA,ITSN1,DNAH17,SLN,OPCML,RBFOX2,ZFYVE9,BEST1,VCAN,PROX1,ZBTB16,RIMS3,DSCAM,PHC2,TTLL7" Drug 1929_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "KIAA1109,FHL1,PKP4,ARHGAP5,ASPH,SON,GART,CLASP2,GLS,OS9,TCF7L2,DNAJC12,RBPJ,DZIP3,C1orf109,KCNMA1,RBM12" Drug 5401_DN Dextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.77E-03 1.00E+00 3.42E-02 3.75E-01 17 192 "FHL1,APC,SLC1A7,CGREF1,BRINP2,ALDH4A1,GNG4,ADGRG1,VAV2,MICAL2,EDRF1,JAKMIP2,RAB3IL1,DNM2,RALGDS,SIDT2,EPB41L1" Drug CID000006395 methanesulfonate Stitch 1.78E-03 1.00E+00 3.43E-02 3.77E-01 8 57 "F3,RYR1,SLC8A2,SLC8A3,SPX,P2RX7,PDYN,KCNT2" Drug ctd:C020806 tetrabromobisphenol A CTD 1.79E-03 1.00E+00 3.46E-02 3.80E-01 54 900 "ASIC1,ACLY,TMEM74,DUSP27,SLC25A25,NDRG2,RTN1,RYR1,FABP7,ADORA1,TUBB4A,FCGR1A,CHST15,FGF1,ELMOD1,APBB1,SORBS1,GPR153,ADGRA1,SNAP25,GFAP,RCOR2,KIRREL3,RND1,ACSBG1,SYT4,DDHD2,TMEM136,CACNA1A,GPR17,EML4,AKNA,GRIK2,USP2,DAAM2,REPS2,PLEKHB1,MS4A7,CHRNB2,PMP2,POU3F2,MAPK8,MASP1,SYTL2,PTCH1,PTHLH,ELMO1,RGMA,KCNA2,RAB3IL1,ABI1,VWA5A,FGFBP3,OLIG2" Drug CID000002185 N-arachidonoylethanolamine Stitch 1.80E-03 1.00E+00 3.47E-02 3.80E-01 19 226 "ASIC1,ADCY2,FOXM1,CCDC80,CACNA1A,CACNA1E,KCNK10,PDE3B,ANLN,FADS2,FTO,VCAN,MAPK8,MAPK10,KCNA1,KCNA2,KCNA4,KCNA6,KCNK1" Drug CID000003518 guanethidine Stitch 1.80E-03 1.00E+00 3.47E-02 3.81E-01 12 113 "ACHE,ADORA1,ADORA3,AGT,SCN4B,ANK2,BCO1,B3GAT1,CACNA1A,CACNA1E,CHRM1,CHRNB2" Drug ctd:D008559 Memantine CTD 1.80E-03 1.00E+00 3.47E-02 3.81E-01 4 14 "ACHE,GFAP,CAMK2A,PRKCG" Drug CID000168491 poly(CA Stitch 1.80E-03 1.00E+00 3.47E-02 3.81E-01 4 14 "FGF1,PAX6,HMGB1,PMS2" Drug CID011469229 "quinoxaline-2,3-dione" Stitch 1.80E-03 1.00E+00 3.47E-02 3.81E-01 4 14 "GRIA1,GRIA2,GRIA4,GRM3" Drug ctd:C012301 domoic acid CTD 1.81E-03 1.00E+00 3.48E-02 3.82E-01 10 84 "CADM3,NPPA,GRIA1,TMEM9,RBFOX2,CHGA,PFKFB3,SF1,ARNT2,OLIG2" Drug CID000005494 TMB-8 Stitch 1.82E-03 1.00E+00 3.49E-02 3.83E-01 16 176 "ADCY2,RYR1,AGT,PLA2G6,ATP2B2,NODAL,CACNB2,LEFTY2,CHRM1,TJP2,CSF3R,PRKCG,PLPPR5,ITGAV,DLG3,ABI2" Drug 3102_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.82E-03 1.00E+00 3.49E-02 3.83E-01 16 176 "ADORA3,FGR,ANK3,AQP4,SLCO1A2,DNAH17,GNG4,USP2,NEURL1,PDE1C,SCRG1,CHI3L2,NCAN,EDRF1,ZBTB16,ITIH2" Drug CID000004680 papaverine Stitch 1.82E-03 1.00E+00 3.49E-02 3.83E-01 16 176 "RYR1,ADORA1,ADORA3,AGT,PDE8B,ABCC8,CACNA1A,CACNA1E,CACNB2,GUCY1A2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CACNG7" Drug CID000001206 MAMP Stitch 1.84E-03 1.00E+00 3.53E-02 3.87E-01 15 160 "MAPT,ADORA1,FOXM1,SLC1A2,MTR,ATM,SOX10,GFAP,ADHFE1,SYT4,ZEB1,AIFM1,PAH,HRH3,PDYN" Drug CID000002156 amiodarone Stitch 1.84E-03 1.00E+00 3.53E-02 3.87E-01 15 160 "ASIC1,AGT,SCN3A,SCN4B,SCNN1D,ASIC4,FOXG1,SCN3B,MYH7,TF,ASIC3,KCNA1,KCNA2,KCNA4,KCND3" Drug 1220_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 3.53E-02 3.87E-01 15 160 "ABAT,MAPT,F3,SORBS1,FYN,TNIK,RGL1,RND1,TGFBR3,PCDH9,PTCH1,DNAJC6,PLPPR4,SRGAP3,EFNA3" Drug 7388_DN PNU-0251126 [267429-19-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "F3,APC,ALDH4A1,FYN,CLASP2,NCDN,MYRF,PSRC1,WWC1,EML4,PCDH9,DZIP3,PTHLH,DLG3,SEC61A2,EN2,EPB41L2" Drug 6677_DN Ciclopirox ethanolamine [41621-49-2]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "KIAA1109,HPCAL4,APC,RPH3A,NDUFA5,KAZN,BTRC,PSRC1,CACNB2,TNS1,DZIP3,TOX,CNIH3,RABGAP1L,PID1,VWA5A,LRRC23" Drug 7176_UP Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "APC,MSR1,ATM,ZSWIM8,INKA2,ACSBG1,ASTN2,SEMA4A,BTRC,MAGI1,ZMYND8,GPR37L1,FADS2,VAV2,GON4L,RALGDS,DTNA" Drug 6981_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "MAPT,PAQR6,WLS,KIAA1109,FHL1,RND1,ASTN2,SEMA4A,PHKG1,CRMP1,FEZ1,PROX1,KCND3,RAB3IL1,DTNA,SSPN,SIDT2" Drug 2275_UP Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "SELL,CDC42BPA,NLGN1,SLC1A7,ATM,ZSWIM8,FGF17,VAMP1,ATF7,CELF3,TNS1,ZMYND8,PTAFR,PTCH1,KCNJ4,TMCC2,ST8SIA3" Drug 1363_DN Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "ASIC1,TESK2,C1orf61,CDC42BPA,ATM,ADAM15,GANAB,OS9,TNS1,CHRNB2,ZFYVE9,PIK3CD,PMS2,MAPK10,PEX5,ABI2,RASGRP2" Drug 6809_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "AGT,SELL,SLCO1A2,ZCCHC24,AJAP1,GNAS,NPPA,SPX,GUCY1A2,NEURL1,CHD5,TOX,RIMS3,PTHLH,ST8SIA3,VWA5A,EPB41" Drug 4289_UP 0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "MDM4,PKP4,APC,SLC2A5,ASPH,CADM3,ACSBG1,VAMP1,GPM6B,GPR17,GRIK3,ZMYND8,JAM2,FLRT1,MAPK10,EDRF1,PHYHIP" Drug 1647_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "RBM10,CDC42BPA,ARFGAP1,ZCCHC24,GNG3,WSCD1,CADM1,UBTF,MICAL1,PACSIN1,OSBPL3,PTCH1,PTHLH,PRDM2,SMG7,L1CAM,VWA5A" Drug 5608_DN Butylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "ADD3,GAS7,AQP4,CAPRIN2,WDTC1,NEUROD1,SEMA4A,GNG3,TCF7L2,NUMA1,TGFBR3,PCDH9,PDE3B,ZFYVE9,KIAA0513,SMG7,RAD52" Drug 2731_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 3.56E-02 3.90E-01 17 193 "SYNDIG1,ACTN2,MDM4,NDRG2,FOXG1,TACC2,SPART,SLCO1C1,GPM6B,GPR19,TF,TGFBR3,CHRNB2,FLRT1,POU3F4,RIMS3,STMN4" Drug CID000001032 propionate Stitch 1.92E-03 1.00E+00 3.65E-02 4.00E-01 21 262 "ACHE,BBOX1,SLC1A2,MTR,DNER,GFAP,HAP1,AKNA,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,CYB561A3,GRM3,PAH,PC,KCNH1" Drug CID000003821 ketamine Stitch 1.92E-03 1.00E+00 3.65E-02 4.00E-01 21 262 "ASIC1,F3,RYR1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,NPPA,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRM3,ASIC3,CHRNB2,CNTN1,KLK6" Drug 1645_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.93E-03 1.00E+00 3.66E-02 4.02E-01 16 177 "ADD3,TUBB4A,PPM1E,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PCDH9,PIK3CD,DNAJC12,KIAA0513,PTCH1,DNAJC6,EFNA3" Drug CID000219132 3-Nitrobenzaldoxime Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 12 114 "SLC1A2,WDTC1,DNER,GPR162,GFAP,GRIA1,GRIA4,GRIN1,AIFM1,ZFP91,HPCA,KCNJ10" Drug CID000004284 DETA Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 12 114 "MAG,ACHE,SEMA6A,SEMA6C,SLIT1,GAD2,NELL1,SEMA4A,ROBO3,CNTN2,OMG,RTN4" Drug CID000449125 LO-1 Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "FOXG1,CNTN2,KCNMA1" Drug CID000473368 "2H-1,2,4-benzothiadiazine" Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "GRIA1,GRIA2,GRIA4" Drug CID011986554 "Titanium, Dichlorobis(.eta.5-2,4-cyclopentadien-1-yl)-" Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "TF,AIFM1,CP" Drug CID000155672 AC1L4ERC Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "ACHE,MT3,CHRM1" Drug CID000004405 NSC517192 Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "ADARB2,ADORA1,ADORA3" Drug CID009549178 A-IZ Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "FOXM1,NHLH1,MAPK10" Drug ctd:C481648 "N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine" CTD 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "ATP1A2,ATP1A3,NPPA" Drug CID003077062 Cp52 Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "MBP,GFAP,CP" Drug CID000193370 CpCp Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "MT3,CHRM1,CP" Drug CID000015383 TMPH Stitch 1.94E-03 1.00E+00 3.67E-02 4.02E-01 3 7 "ACHE,HRH3,KCNMA1" Drug CID000005053 Pyrethroids Stitch 1.95E-03 1.00E+00 3.67E-02 4.02E-01 9 71 "ACHE,SCN4B,ATP2B2,SCN3B,SOX10,GFAP,CHGA,ASIC3,CAMK1G" Drug ctd:D014638 Vanadates CTD 1.95E-03 1.00E+00 3.67E-02 4.02E-01 73 1303 "EPS8,LGR4,MEG3,EYA1,RTKN,TMEM156,CHST15,ASRGL1,CNIH2,PPM1E,APBA2,CACHD1,ZNF365,SLC2A5,MSR1,SMARCE1,SNAP25,TNIK,ADGRB2,DNER,NFASC,NCAM1,STOX1,RGL1,NFIA,GNG4,ANO4,VXN,PSD3,TF,OLR1,TGFBR3,FBXL16,PAX6,CDH10,TPD52,PDE1C,CIART,ADGRG1,PFKFB3,TUB,SERPINE2,NEGR1,DNAJC12,FTO,MED1,FEZ1,PRKAB2,FMN2,PLPP4,PRKCZ,CTNND1,TOX,SYTL2,SYNC,PMEPA1,MED24,PTPRE,NTM,CCDC3,ARNT2,KCNK2,KCNMA1,CAB39L,PID1,RASGRF1,L1CAM,CAMK1G,ATL1,TTLL7,SSPN,RAVER2,EPB41" Drug CID000072032 2-(aminomethyl)pyrrolidine Stitch 1.96E-03 1.00E+00 3.67E-02 4.02E-01 15 161 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3,APC,ATP2B2,GFAP,GPR17,GPR26,P2RX7,P2RY12,PRKACB,KCNMA1,LPAR6" Drug 6642_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "ARID1A,TUBB4A,PLA2G6,APC,CCDC88A,ASPH,ALDH4A1,BTRC,PDE1C,PLEKHB1,CCSER2,SMG7,PTPRE,DLG3,RAB5B,ROM1,PLEKHO1" Drug 4492_DN Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MAPT,KIAA1109,APBB1,BCAN,ALDH4A1,ADGRB2,BTRC,GPM6B,TNS1,STMN4,PARD6A,KIF2A,PID1,RAD52,NUP214,RGS10,SIDT2" Drug 5418_UP Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "NDRG2,APC,BCO1,PKNOX2,ASPH,EMC1,RND1,GLS,PDE3B,ZFYVE9,PIK3CD,ARHGEF4,MAPK8,SYNC,ITIH2,KCNK1,DTNA" Drug 3989_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "DOCK10,CCDC181,PHLDB1,SLCO1C1,ACSBG1,SPX,PLEKHB1,ST8SIA5,VAV2,IFFO1,ARHGEF4,NTM,RABGAP1L,KCNN3,BEND5,ABCC9,ROM1" Drug 4709_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "PLA2G6,FHL1,APC,ASPH,GAD2,GUCY1A2,MAGI1,CRMP1,MICAL2,VCAN,RIMS3,KCND3,ATN1,ST8SIA3,SSPN,VWA5A,ELAVL3" Drug 6457_UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MAPT,EMID1,ACTN2,SEMA6A,CDC42BPA,GAS7,EMC1,NDUFA5,GPM6B,OPCML,SPX,ATRNL1,GON4L,SRGAP3,RAB5B,ATN1,ST8SIA3" Drug 4310_UP Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "SYNDIG1,HPCAL4,NTNG1,SLC6A9,WDTC1,VAMP1,NUCB1,NEURL1,PTGDR2,ADGRG1,CA14,RIMS3,ATN1,DTNA,ABCC9,CRTAC1,RGR" Drug 2469_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MDM4,NDRG2,KIAA1109,RASA3,ZCCHC24,ADAM15,RAP1GAP2,CACNA1A,TCF7L2,VCAN,PKN2,RIMS3,PTCH1,KIF2A,RAD52,PLEKHO1,LRRC23" Drug 582_DN butein; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MBP,CLIP1,C1orf61,FYN,ADGRB2,NAP1L2,GLS,PSD3,TUB,CHRNB2,CCSER2,CNTN1,PACSIN1,IFFO1,HP1BP3,CAMK1G,EN2" Drug 3938_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MOBP,FOXG1,SLC1A7,PKNOX2,SLC6A9,PDE8B,NPAS3,PRUNE2,P2RX7,KCNK10,CDH10,CHRNB2,DUSP26,CAMKV,POU3F2,PTAFR,NTM" Drug 3377_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "ASIC1,CDC42BPA,APC,SLC1A7,ATM,EMC1,NDUFA5,PSD3,TGFBR3,PCDH9,ZMYND8,MED1,CTNND2,NOS1AP,HP1BP3,RAD52,ATN1" Drug 3716_UP Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "KIAA1109,BCAS1,ZSWIM8,B4GALNT1,NFASC,INKA2,GPR19,TNS1,PCDH9,HRH3,CHI3L2,SULT4A1,IFFO1,POU3F4,RIMS3,RABGAP1L,DTNA" Drug 5695_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "ADCY2,ADORA1,FGF1,SEMA6A,SORBS1,SLC2A5,AJAP1,PSD3,PHKG1,PIK3CD,CABP1,MAPK8,MAGI2,PARP11,ST8SIA3,LMO1,VWA5A" Drug 3606_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MDM4,NDRG2,F3,APC,RPH3A,ASPH,ATM,ZCCHC24,TCF7L2,PCDH9,ZMYND8,ZFYVE9,EDRF1,SYTL2,PTHLH,DTNA,RGS10" Drug 5398_UP Azacyclonol [115-46-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "ASIC1,PLA2G6,AMPH,APBA2,TAGLN3,TNIK,NCAM1,GLS,WSCD1,NRGN,GRIN1,SCRG1,NRXN1,CRMP1,SYNC,KCND3,TTLL7" Drug 2959_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "C1orf61,ITSN1,APC,SHANK2,ATP1A3,ALDH1L1,RND1,TNS1,RBFOX2,UBTF,NMT2,CCSER2,POU3F4,PKN2,PRKCZ,KCNMA1,LRRC23" Drug 4626_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "DPF1,EMID1,ASIC4,ANK3,TAGLN3,DDX25,PHLDB1,KLHL4,GPM6B,PTGDR2,ADGRG1,SPATA6,POU3F2,CNIH3,KIF2A,SIDT2,RASGRP2" Drug 6741_UP Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "ADORA3,FGF1,GAS7,BCAS1,KIF21B,BCL2L2,KAZN,PRUNE2,OPCML,HRH3,TPM3,COL9A2,IGSF1,SMG7,KCND3,KCNH1,PARP11" Drug 3725_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "FGF1,FOXG1,PPFIA1,ADAM15,ADGRB2,MLC1,GNAS,BTRC,GPM6A,PLEKHB1,PIK3CD,CTNND2,PTCH1,CNIH3,AK5,PID1,DTNA" Drug 607_UP butein; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "PRR5L,MAPT,MBP,SYNDIG1,PAQR6,FABP7,ALDH4A1,WDTC1,NAP1L2,SPART,GPR19,NRGN,PADI2,SEZ6L,PDE1C,KIAA1549L,VWA5A" Drug 3906_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "CEND1,MOBP,APC,AQP4,ASPH,FYN,ZCCHC24,GLS,MYRF,PRUNE2,OPCML,HRH3,PDE4B,CA14,CHRNB2,CABP1,SSPN" Drug 3354_DN (-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "APBA2,APC,PDE8B,ASPH,ZCCHC24,SPART,POPDC3,BTRC,HAP1,NEURL1,TNS1,SDC3,RAB3IL1,RAD52,DTNA,VWA5A,LRRC23" Drug 2311_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "FHL1,C1orf61,SELL,BCO1,GAD2,SLCO1C1,CACNA1A,PRUNE2,GRIA4,SEZ6L,VAV2,SNCAIP,SDC3,PTCH1,ITIH2,KCND3,RASGRP2" Drug 3245_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "NDRG2,F3,MOBP,CDC42BPA,SLC1A2,MSR1,SHANK2,PDE8B,GAD2,NDUFA5,POPDC3,CACNB2,DAAM2,CNTN1,CRMP1,PLPPR1,RAB3IL1" Drug 3302_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.97E-03 1.00E+00 3.67E-02 4.02E-01 17 194 "MAPT,PAQR6,ACTN2,MOBP,INKA2,BTRC,GPM6B,PDE3B,PIK3CD,SULT4A1,CNTN1,PACSIN1,CRMP1,MAPK8,NOS1AP,JAKMIP2,PTHLH" Drug CID000023715 D90A Stitch 1.98E-03 1.00E+00 3.67E-02 4.03E-01 10 85 "SLC1A2,DNER,GFAP,GRIA1,GRIA2,GRIA4,GRM3,ZFP91,RTN4,NUP214" Drug CID000066393 "estradiol-2,3-quinone" Stitch 1.98E-03 1.00E+00 3.67E-02 4.03E-01 10 85 "SLC25A25,AQP4,GFAP,GRIA1,GRIA2,GRIA4,TNR,PDE1A,PDYN,POU3F2" Drug ctd:C015559 trimellitic anhydride CTD 1.98E-03 1.00E+00 3.68E-02 4.03E-01 101 1913 "SERPINA3,MAP6,ASIC1,LGR4,RTN3,IL17D,WLS,NDRG2,PLEKHG5,RXRG,CDC7,FABP7,TUBB4A,FOXRED2,FOXM1,SFPQ,DOCK10,NTNG1,GPAM,BCAN,CACHD1,LRRC4C,SCG3,SLCO1A2,ASPH,MTR,ASTN1,ATP1A2,ATP2B2,SCN3B,ARPP21,GART,CPLX2,FXYD6,NASP,COLGALT2,NFIA,MLC1,RHBDL3,C1QC,KAZN,ROBO3,PSRC1,PRUNE2,WSCD1,GPM6A,VWC2,B4GALNT4,NUDT21,ADAMTS8,GPR88,TGFBR3,FBXL16,TJP1,AIFM1,TNS1,DCLK1,MAGI1,PDE1A,PDE1C,ACOT7,ADGRG1,CADM1,NRXN1,NRXN2,ANLN,FAM181B,CNTN1,MEAF6,NECAB2,NSD2,PPP2R5C,SNCAIP,PROX1,BRINP3,ACY3,SPIRE1,TOMM20,PSMD13,ITGAV,SHD,RGMA,PTPRD,KCNA6,SMG7,SRGAP3,KCNJ10,OLIG1,RAB3IL1,KLRC3,TMEM255A,PLEKHB2,DSCAM,ABCC9,CRTAC1,RGR,SYT15,ARHGAP12,EPB41,EPB41L1,RCAN2" Drug CID000005537 trequinsin Stitch 1.99E-03 1.00E+00 3.69E-02 4.05E-01 8 58 "ADD3,FGF1,PTPN5,PDE1C,PDE2A,PDE3B,PDE4B,HPR" Drug CID006435801 D-CPPene Stitch 2.01E-03 1.00E+00 3.72E-02 4.08E-01 6 34 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3" Drug CID000002073 NSC15627 Stitch 2.01E-03 1.00E+00 3.72E-02 4.08E-01 6 34 "SCN4B,SCN3B,CACNB2,ASIC3,KCNA2,KCNA4" Drug CID000001678 3-nitropropionic acid Stitch 2.04E-03 1.00E+00 3.77E-02 4.14E-01 16 178 "ADORA1,ADORA3,FOXG1,SLC1A2,GAD2,GFAP,ABCC8,CACNA1A,PAH,HPR,SLC25A27,PACSIN1,PRTFDC1,STMN4,ATN1,EN2" Drug ctd:C026690 cerous chloride CTD 2.04E-03 1.00E+00 3.77E-02 4.14E-01 16 178 "MEG3,NDRG2,SFPQ,PI16,DOCK10,GPR153,CSPG5,SNCB,NKX6-2,CLASP2,DCLK1,NEGR1,SF1,PTPA,KLK6,KCNJ4" Drug CID000445141 AC1L9HHR Stitch 2.08E-03 1.00E+00 3.80E-02 4.17E-01 26 354 "ACLY,MBP,F3,ADCY2,TUBB4A,FOXG1,ANK1,ANXA7,DGKZ,GPAM,DGKD,RPH3A,NRGN,OLR1,P2RX7,AIFM1,PIK3CD,PMP2,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,SYTL2,RBM12,EPB41" Drug 7372_UP Ofloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "EMID1,ARID1A,TUBB4A,FGF1,PPFIA1,MADD,SEMA4A,ARHGAP19,KIAA1549L,NSD2,PTHLH,SMG7,RABGAP1L,RAD52,DTNA,RGS7,PLEKHO1" Drug 4162_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "ADCY2,KLRC4,TAGLN3,BRINP2,NMNAT2,PHLDB1,ACSBG1,GPM6A,TF,GUCY1A2,HPSE2,CHRNB2,ATRNL1,ATN1,FAM13C,L1CAM,ROM1" Drug 2444_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "EMID1,MDM4,FHL1,FOXG1,RASA3,SLC1A7,CCDC88A,ADAM15,NDUFA5,KAZN,TPD52,COL9A2,OSBPL3,RAB3IL1,EFNA3,LPAR6,RASGRP2" Drug 4267_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "DPF1,SYNDIG1,KIAA1109,MOBP,SCN3B,WDTC1,NEUROD1,PRUNE2,KCNK10,ADGRG1,ARHGEF4,CTNND2,MAPK8,PRDM2,KCND3,ATN1,RGR" Drug 3816_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "EMID1,MOBP,BCAS1,SLC8A2,NPAS3,INKA2,CACNA1A,HAP1,USP2,DCLK1,CHRNB2,CADM1,PRRX1,SPATA6,MAPK8,KCNMA1,DTNA" Drug 6215_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "ASIC1,SLC1A7,SLN,GLS,VAMP1,GNG4,BTRC,CACNA1A,PRUNE2,DAAM2,SERPINE2,ZFYVE9,MAPK10,GON4L,SYNC,RAD52,ATN1" Drug 4300_UP Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "FOXRED2,ASIC4,PKP4,SLC1A2,MSR1,PDE8B,VAMP1,GNG4,INA,PDE3B,CHI3L2,CADM1,RIMS3,PRDM2,DTNA,RET,RGR" Drug 3553_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "CDC42BPA,BCAS1,BCO1,ALDH4A1,NDUFA5,GFAP,ACSBG1,GNAS,OPCML,KCNK10,PDE4B,RGS6,OSBPL3,ARHGEF4,PTHLH,NUP214,OLIG2" Drug 5564_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "MBP,TMEM156,AQP4,BCO1,SLCO1A2,TNIK,NCAM1,ALDH1L1,KAZN,WSCD1,ZEB1,PTGDR2,ZFYVE9,SULT4A1,PTCH1,NTM,ELAVL4" Drug 4705_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "HPCAL4,FOXG1,SORBS1,NLGN1,CCDC88A,ATM,CCDC181,DKK3,ADGRB2,TLL2,ZMYND8,GPR37L1,TUB,VAV2,CHD5,SMG7,SRGAP3" Drug 4232_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "ASIC1,FGF1,SEMA6A,GAS7,ATP2B2,PHLDB1,BTRC,ADGRL3,KLHL4,ADAMTS8,TNS1,CADM1,CABP1,MICAL2,MAPK8,KIF2A,RET" Drug 3757_UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "CDHR1,ACTN2,NDRG2,RASA3,DNAH17,ATP2B2,SLCO1C1,VAMP1,PADI2,SCRG1,TMPRSS5,CHI3L2,CABP1,KCND3,ARNT2,ATN1,RAVER2" Drug 4581_DN Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "ANK3,TNIK,VAMP1,ASTN2,BTRC,CACNA1A,GRIK2,TNS1,SF1,PROX1,SYTL2,PTHLH,RAD52,RGS10,SIDT2,ELAVL3,LRRC23" Drug 2180_UP Heliotrine [303-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "MOBP,ANK3,PKNOX2,SNAP25,NPAS3,SPART,FGF17,GPM6B,TJP1,PCDH9,CTNND1,MASP1,SYTL2,KCNMA1,PARP11,ST8SIA3,TTLL7" Drug 1785_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "EPS8,ADCY2,PPM1E,NTNG1,SLC1A7,ASPH,SPART,NCAM1,GLS,GOLGB1,NRGN,ACOT7,OSBPL3,PRKACB,MAPK10,DTNA,LPAR6" Drug 3272_UP SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "RYR1,APC,SLC2A5,BCO1,PKNOX2,ASPH,POPDC3,WSCD1,NUMA1,SERPINE2,CRMP1,PLPPR1,PTHLH,SMG7,PARD6A,RAB3IL1,ATN1" Drug 6870_DN SC-560; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "KIAA1109,CDC42BPA,GAS7,ADAM15,BTRC,NUCB1,NUMA1,RBFOX2,CHRNB2,SERPINE2,CHD1L,MAPK8,SMG7,PEX5,ATG16L1,ATN1,EFNA3" Drug 4223_UP Nystatine [1400-61-9]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "APC,ASCL1,ADGRB2,NEUROD1,GPR88,TMEM257,LILRA4,HPSE2,PLEKHB1,VAV2,CABP1,CTNND2,KCND3,SRGAP3,ARNT2,SUSD4,SLC6A15" Drug 4481_DN Amidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "MAPT,PAQR6,APBB1,CGREF1,BTRC,GPR19,TGFBR3,TNS1,MED1,MAPK8,PTHLH,PTPRE,TMCC2,ATG16L1,DTNA,RGS7,TTLL7" Drug 6330_UP Budesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "ARID1A,ADORA1,FGF1,HPCAL4,SH3GL2,PKNOX2,SORCS3,ATP1A2,TNIK,MLC1,NUMA1,TNS1,CHRNB2,RABGAP1L,NAV2,DTNA,EFNA3" Drug 5440_UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "EYA1,ADORA1,FHL1,ATP1A3,ZCCHC24,NMNAT2,ACSBG1,POPDC3,WSCD1,SEZ6L,SULT4A1,SPATA6,POU3F4,KCNC1,KCNMA1,DNAH9,ST8SIA3" Drug 4552_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "DPF1,MAG,KCNIP2,PLA2G6,HPCAL4,NPAS3,VAMP1,TMEM257,PC,PDE3B,NRXN2,SPATA6,CTNND2,NOS1AP,MAGI2,NUP214,RCAN2" Drug 2517_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 3.80E-02 4.17E-01 17 195 "SEMA6A,BBOX1,ANK3,ST8SIA1,SNAP25,ATP2B2,ARPP21,ADGRB2,NEUROD1,TCF7L2,GUCY1A2,SEZ6L,LILRA4,PRDM2,KCND3,RASGRF1,EPB41" Drug CID000017429 FP-I Stitch 2.12E-03 1.00E+00 3.81E-02 4.18E-01 7 46 "APBB1,GFAP,ADHFE1,PDYN,ZFYVE9,RBPJ,PTHLH" Drug ctd:C030691 gluconic acid CTD 2.12E-03 1.00E+00 3.81E-02 4.18E-01 7 46 "RXRG,SEMA6C,FYN,SLC22A6,SIRPA,KCNC1,ARNT2" Drug ctd:D003932 Heroin CTD 2.12E-03 1.00E+00 3.81E-02 4.18E-01 7 46 "ACTN2,AMPH,SNAP25,PDYN,PMEPA1,BLOC1S6,SV2A" Drug CID000108107 benzamil Stitch 2.15E-03 1.00E+00 3.81E-02 4.18E-01 9 72 "ASIC1,AGT,SCN4B,SCNN1D,FOLH1,MTR,SCN3B,GRIA4,ASIC3" Drug CID000000194 AC1L1IO7 Stitch 2.15E-03 1.00E+00 3.81E-02 4.18E-01 9 72 "MBP,ADORA1,ADORA3,NHLH1,NUDT21,P2RX7,P2RY12,PYGM,LPAR6" Drug ctd:D001464 Barium CTD 2.15E-03 1.00E+00 3.81E-02 4.18E-01 9 72 "GNG3,CACNA1A,CACNA1E,P2RX7,CHRNB2,KCNH1,KCNJ4,KCNJ10,KCNK1" Drug ctd:D004237 Diuron CTD 2.16E-03 1.00E+00 3.81E-02 4.18E-01 93 1742 "SERPINA3,RPL38,PRR5L,ACHE,EMID1,LGR4,PAQR6,MRVI1,F3,CLIP1,RTN1,ADD3,AGT,FGF1,FHL1,SFPQ,ANK2,PI16,ANXA7,PKP4,CCDC80,TACC2,SLC1A6,SLC6A9,SLC14A1,SCMH1,SMARCE1,ATP1A2,FYN,ZCCHC24,CADM3,ILDR2,KIF1B,STARD10,DNER,NAP1L2,SMOC1,GLS,C1QC,SEMA4A,WWC1,CNDP1,GPM6A,ZEB1,HAP1,EML4,DDR2,TF,GUCY1A1,ZFP91,PC,TNS1,DCLK1,HRH3,TPD52,TPM4,PDE2A,PLEKHB1,MS4A7,JAM2,SERPINE2,CADM1,ANLN,CPT1C,FADS2,PRRX1,P2RY12,CP,MED1,NKAIN4,FEZ2,MICAL2,VCAN,PRKACB,DZIP3,PLD5,TOX,ZC3H11A,PTPRO,PTPRZ1,RABGAP1L,NAV2,DLG3,OLIG1,RAB5B,KLRC3,JMJD1C,RGS10,VANGL2,SSPN,LPAR6,EPB41L2,RASGRP2" Drug 6551_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "TUBB4A,ZNF365,PKNOX2,FYN,ZCCHC24,KIF21B,RGL1,ACSBG1,GLS,PCDH9,PIK3CD,DNAJC12,DZIP3,RIMS3,DNAJC6,EFNA3" Drug CID000002554 carbamazepine Stitch 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "ABAT,ASIC1,ADCY2,ADORA1,ADORA3,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,PC,ASIC3,DPYSL5,PTCH1,KCNA1,EPB41" Drug CID000001066 quinolinic acid Stitch 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "ACHE,FGF1,B3GAT1,GAD2,ARPP21,GFAP,GFRA1,GRIK3,GRIK4,GRM3,ZFP91,PAH,PDYN,PACSIN1,ATN1,EN2" Drug 7005_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "ADD3,PPM1E,CCDC88A,FYN,ZCCHC24,RGL1,RND1,ACSBG1,GLS,BTRC,PCDH9,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3" Drug 5086_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "MAPT,TESK2,SORBS1,SLC2A5,FYN,TNIK,ZCCHC24,RGL1,GLS,USP2,PCDH9,DNAJC12,KIAA0513,DNAJC6,PLPPR4,EFNA3" Drug 6045_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "MAG,ACTN2,CDC42BPA,APC,ASTN1,FYN,ATP2B2,NHLH1,ATF7,ZEB1,ADAMTS8,HRH3,CAMKV,SULT4A1,PMP2,KCNJ4" Drug 4452_UP geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.16E-03 1.00E+00 3.81E-02 4.18E-01 16 179 "ACTN2,GRAMD1B,FOXG1,SNAP25,NFASC,NUCB1,PDE4B,SF1,PRKCZ,MAPK8,EDRF1,PHYHIP,PTHLH,SMG7,TTLL7,VWA5A" Drug CID000002754 cilostazol Stitch 2.16E-03 1.00E+00 3.81E-02 4.18E-01 10 86 "AGT,OLR1,AIFM1,PDE1C,PDE2A,PDE3B,PDE4B,TJP2,P2RY12,KCNMA1" Drug 4825_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FOXG1,APC,PDE8B,CADM3,ALDH1L1,VAMP1,POPDC3,CDH8,ASIC3,IFFO1,CHD5,FAM131B,ITIH2,PRDM2,PTPRD,EN2,RASGRP2" Drug 403_UP alpha-estradiol; Up 200; 0.01uM; ssMCF7; HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "SYNDIG1,EYA1,NDRG2,C1orf61,BCAS1,RPH3A,NMNAT2,LMO3,ALDH1L1,FGF17,AJAP1,HAP1,TLL2,NEURL1,ATRNL1,SDC3,RGR" Drug 4324_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ACHE,ADCY2,FGF1,MOBP,AMPH,RASA3,PKP4,ADAM15,OPCML,TPM3,SF1,PROX1,PTAFR,SMG7,ATG16L1,RASGRF1,DTNA" Drug 5320_UP Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FHL1,ITSN1,ASPH,ALDH4A1,BTRC,PSRC1,TCF7L2,NRGN,ADGRG1,DZIP3,BRINP3,PEX5,ATN1,DSCAM,NUP214,SSPN,LRRC23" Drug 4683_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FOXRED2,AGT,C1orf61,GAS7,SORBS1,B4GALNT1,PHLDB1,ASTN2,OPCML,PLEKHB1,DZIP3,ATN1,FAM13C,DTNA,RGS10,EFNA3,ROM1" Drug 3517_UP Torsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ARID1A,MOBP,APBA2,ZCCHC24,VAMP1,WSCD1,GPM6B,PDE3B,KIAA1549L,SPATA6,PACSIN1,MICAL2,NOS1AP,RAB3IL1,DTNA,NUP214,RCAN2" Drug 4321_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "EMID1,C1orf61,CSPG5,SLCO1A2,TAGLN3,CADM3,B4GALNT1,NHLH1,PRUNE2,GPR17,SEZ6L,ARHGAP22,PHYHIP,AK5,RASGRF1,DTNA,EPB41L2" Drug 3572_UP Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NDRG2,CDC42BPA,BCAS1,RPH3A,BCO1,PKNOX2,GPR153,WDTC1,NMNAT2,RND1,OPCML,TNS1,POU3F2,NOS1AP,ATN1,SIDT2,EFNA3" Drug 2430_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MAPT,CEND1,FGF1,MOBP,APBA2,ALDH4A1,WDTC1,PHLDB1,GPM6B,GRIN1,GUCY1A2,UBTF,SULT4A1,EDRF1,KCNMA1,BEND5,SEC61A2" Drug 7208_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MAPT,BBOX1,AMPH,ITSN1,SORBS1,SLC6A9,ZCCHC24,CADM3,PHLDB1,GLS,CAMK2G,NEURL1,ZFYVE9,PTPRE,KCNMA1,RAD52,RASGRF1" Drug 5301_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "F3,ITSN1,SYBU,ASPH,RCOR3,ALDH4A1,ATM,NASP,CLASP2,NDUFA5,GANAB,PPP2R5C,EDRF1,JAKMIP2,NAV2,EFNA3,EPB41L2" Drug 2441_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "WLS,KIAA1109,APC,SHANK2,PDE8B,WDTC1,RND1,CAMSAP2,NPPA,CACNB2,GUCY1A2,P2RX7,TJP1,PDE4B,CHRNB2,KCND3,PLEKHO1" Drug 1686_UP Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MDM4,APC,GPR153,TNIK,ALDH1L1,INKA2,ARHGEF7,POPDC3,GNG3,CACNB2,GPR19,MAPK8,PRDM2,RABGAP1L,KCNMA1,ATG16L1,SEC61A2" Drug 6401_UP F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "DPF1,MAPT,APBA2,APC,GAS7,SORBS1,ALDH4A1,CADM3,COLGALT2,SLCO1C1,CACNB2,CHRNB2,ITIH2,PTPRE,RAB3IL1,TTLL7,PLEKHO1" Drug 6060_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ACTN2,ADORA1,CCDC88A,DLL3,ZSWIM8,FGF17,TNS1,PTGDR2,PRRX1,TENM4,SDC3,PLPPR1,KCNMA1,ATN1,ST8SIA3,LMO1,LRRC23" Drug 4141_UP Metronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ACTN2,MDM4,FOXRED2,KIAA1109,APBA2,SLC1A2,SLC2A5,ATP1A3,ATP2B2,WSCD1,NEURL1,CDH10,ACOT7,VAV2,ELMO1,KCNMA1,ATN1" Drug 6676_UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "DPF1,SYNDIG1,CEND1,SORBS1,ATP2B2,GAD2,HAP1,TPM3,TUB,CHD5,PKN2,MAPK8,MAGI2,CDH20,SRGAP3,KCNJ9,RASGRF1" Drug 2726_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "SYNDIG1,ACTN2,MDM4,FHL1,FOXG1,NTNG1,SYBU,BCO1,PKNOX2,SHANK2,BCL2L2,INKA2,GPM6B,NPPA,GUCY1A1,ZFYVE9,FLRT1" Drug 1271_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ABAT,SYNDIG1,ECSIT,CDC42BPA,APC,GART,CAMSAP2,CACNB2,CDC42,VAV2,CTNND1,RIMS3,PTAFR,SMG7,SV2A,RAP1GAP,LPAR6" Drug 3401_UP Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "SYNDIG1,CEND1,WLS,FHL1,FOXG1,ATP1A2,LMO3,VAMP1,CDH8,PLEKHB1,VCAN,CNIH3,TMCC2,KCNMA1,NUP214,ST8SIA3,LRRC23" Drug 7102_UP 0198306-0000 [212631-61-3]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,FGF1,FOXG1,ANK3,CSPG5,ASPH,ALDH4A1,COLGALT2,WWC1,CDH8,TPM4,CHD1L,MED1,SDC3,PTCH1,ITIH2,BEND5" Drug 2198_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,SYNDIG1,MDM4,MOBP,ITSN1,CAMSAP2,WWC1,GPR19,NUMA1,PSD3,USP2,PADI2,ZFYVE9,RGS10,ARHGEF10L,SIDT2,RASGRP2" Drug 6435_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "SCN3A,B3GAT1,PHLDB1,GPM6A,RBFOX2,ZMYND8,ACOT7,PLEKHB1,MICAL1,NSD2,CHD1L,VCAN,PTPRE,SRGAP3,SLC17A6,L1CAM,NUP214" Drug 3739_DN Foliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FGF1,MOBP,FOXG1,SELL,CGREF1,SLN,MYRF,CACNA1A,NUMA1,GRIK2,PIK3CD,MICAL2,ARHGEF4,PLPPR1,PARD6A,VWA5A,ELAVL3" Drug 6832_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "EXTL1,MDM4,FABP7,AQP4,RPH3A,SLC1A7,SLC2A5,SHANK2,ASCL1,ZCCHC24,ATF7,BRSK2,TNS1,PTGDR2,ADGRG1,PTAFR,NUP214" Drug 5849_UP Glibenclamide [10238-21-8]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FOXRED2,PKP4,APC,SLC1A7,SLN,ATP1A3,CACNA1A,SEZ6L,CHGA,VAV2,MASP1,KCNJ4,RALGDS,DTNA,SLC6A15,VWA5A,ROM1" Drug 363_UP sodium 4-phenylbutyrate; Up 200; 100uM; HL60; HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NDRG2,FOXRED2,ITSN1,ZCCHC24,CADM3,ZSWIM8,SPART,VAMP1,CHRM4,FLRT1,SULT4A1,ARHGEF4,ECE2,HP1BP3,C1orf109,DLG3,RLBP1" Drug 2317_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "APC2,GLS,WSCD1,HPSE2,GDAP1L1,PIK3CD,CNTN1,CABP1,RIMS3,ITIH2,RAB3IL1,RAD52,DSCAM,L1CAM,ABCC9,RCAN2,RASGRP2" Drug 5937_DN LY294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NDRG2,FOXRED2,SEMA6A,APC,BCO1,B4GALNT1,AJAP1,ASTN2,CRMP1,SDC3,ARHGEF4,BRINP3,RABGAP1L,DTNA,RET,RGS10,RBM12" Drug 366_UP Gleevec; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "RBM10,GAS7,BCAS1,EMC1,NPPA,NRGN,ATP13A2,ARHGAP19,FADS2,PMS2,NSD2,MAPK8,DSCAM,L1CAM,NUP214,SIDT2,LRRC23" Drug 3783_DN Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "HPCAL4,CDC42BPA,SLC6A9,CGREF1,TAGLN3,GAD2,ADGRB2,HAP1,NEURL1,TNS1,CDH10,PTGDR2,RIMS3,GON4L,RAD52,SUSD4,PLEKHO1" Drug 2969_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MDM4,NDRG2,ADORA3,CDC42BPA,ANK3,PALLD,CAMSAP2,PSD3,TJP1,NEURL1,TNS1,VCAN,PKN2,ZBTB16,PTAFR,RET,RASGRP2" Drug 3351_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,CDC42BPA,PDE8B,ASPH,EMC1,SPART,GLS,GNG3,TCF7L2,NUMA1,ADGRG1,PPP2R5C,MAPK10,SYNC,PEX5,RAD52,LRRC23" Drug 4087_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "DPF1,C1orf61,ANK1,NTNG1,GAS7,SPART,ATF7,CNTN1,NECAB2,SPATA6,CTNND2,MAPK8,PRDM2,KCND3,ARNT2,SLC17A6,DSCAM" Drug 3359_DN Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,GPR153,INKA2,VAMP1,POPDC3,PSD3,OPCML,TGFBR3,CDH10,PDE3B,ZFYVE9,FADS2,CNTN1,MAPK8,RIMS3,RAD52,VWA5A" Drug 3314_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FOXG1,C1orf61,TAGLN3,ATM,SOX10,NDUFA5,INKA2,ROBO3,WSCD1,USP2,NEURL1,SEZ6L,NECAB2,JAKMIP2,KCNMA1,RAB3IL1,SSPN" Drug 3923_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FGF1,FHL1,SORBS1,PKNOX2,CADM3,NMNAT2,COLGALT2,NEUROD1,NPPA,GRIA4,NEURL1,HRH3,SEZ6L,PIK3CD,VCAN,USH1C,ELAVL3" Drug 2530_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FOXG1,ASCL1,PDE8B,SLN,FXYD6,GNG4,CAMSAP2,MYRF,OPCML,CHI3L2,DUSP26,NMT2,CTNND2,MAPK10,EDRF1,ST8SIA3,SIDT2" Drug 5527_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "APC,SYBU,URGCP,SHANK2,PHLDB1,BTRC,NUCB1,GUCY1A2,KCNK10,PTGDR2,FEZ1,VCAN,EDRF1,PLPPR1,NUP214,SIDT2,VWA5A" Drug 5270_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NDRG2,APBA2,APC,PDE8B,ASPH,WDTC1,ZCCHC24,GLS,GNG3,GUCY1A2,CDH8,ADGRG1,MED1,MAPK8,SMG7,DTNA,EPB41L2" Drug 3816_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NTNG1,RPH3A,CGREF1,TAGLN3,ATP1A3,B4GALNT1,GNG3,GPM6A,GPM6B,GPR17,PLEKHB1,IFFO1,CRMP1,ITIH2,PRDM2,RAB3IL1,RGS10" Drug 2961_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ARID1A,FOXG1,ANK3,CGREF1,ALDH1L1,RND1,MYRF,BTRC,CACNA1A,RBFOX2,ZFYVE9,CCSER2,BEST1,CTNND2,BEND5,SEC61A2,ABI2" Drug 5232_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,RBM10,CDC42BPA,ARFGAP1,DLL3,ASPH,ZCCHC24,KAZN,FADS2,SF1,NOS1AP,RIMS3,SMG7,KCND3,ATN1,RGS10,SIDT2" Drug 6824_UP Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,RYR1,ADORA1,FGF1,BCAN,AQP4,WDTC1,ZCCHC24,PHLDB1,AJAP1,POPDC3,ATF7,FADS2,SULT4A1,VCAN,KCNMA1,ELAVL3" Drug 4256_DN Tocainide hydrochloride; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MAPT,ALDH1L1,VAMP1,GNG3,GRIK2,CDH10,ZMYND8,VAV2,PMP2,SPATA6,VCAN,EDRF1,KCND3,PARP11,RALGDS,FAM13C,RGS7" Drug 6647_UP Estrone [53-16-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "SYNDIG1,B3GAT1,ATM,KIF21B,NHLH1,HAP1,ADAMTS8,P2RX7,CDH10,PDE4B,ADGRG1,SULT4A1,SPATA6,MAGI2,PTPRO,DSCAM,DTNA" Drug 6646_UP Progesterone [57-83-0]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "AGT,APBB1,SLC1A7,PDE8B,BTRC,DAAM2,CDH10,CADM1,CNTN1,PLCH2,CHD5,PRDM2,KCND3,SRGAP3,DSCAM,FAM13C,DTNA" Drug 1713_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "PAQR6,NDRG2,ADD3,KIAA1109,APBA2,CCDC88A,INA,NEURL1,TNS1,ZFYVE9,CCSER2,OSBPL3,SMG7,DNM2,ABI2,BSCL2,PLEKHO1" Drug 6101_UP Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "EMID1,NDRG2,FHL1,APC,RPH3A,PKNOX2,GPR153,B3GALT2,PRUNE2,KCNK10,DAAM2,PAX6,HPSE2,CA14,ARHGEF4,PROX1,STMN4" Drug 1681_UP Epirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "F3,ADD3,FOXG1,GAS7,BCAN,ZCCHC24,ALDH1L1,GNG4,TCF7L2,TNS1,PCDH9,PTGDR2,RBFOX2,MAPK8,KCNMA1,ATN1,RGS10" Drug 3524_DN Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "WLS,FHL1,BCAS1,CAPRIN2,ATM,EMC1,PHLDB1,AJAP1,POPDC3,BTRC,CAMK2G,PCDH9,ZMYND8,RIMS3,RALGDS,C12orf4,DTNA" Drug 2862_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,MAPT,ARID1A,PLA2G6,NDUFA5,VAMP1,CACNB2,ZEB1,GRIK3,GRM3,OPCML,CDC42,ADGRG1,FLRT1,MAPK8,SYNC,DNAH9" Drug 4578_UP Apigenin [520-36-5]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "PAQR6,PLA2G6,SELL,RASA3,APBB1,GAS7,SLC1A7,CADM3,HAP1,HPCA,CRMP1,CTNND2,MAPK10,PRDM2,KCND3,RASGRF1,RASGRP2" Drug 6074_UP Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "RYR1,AGT,SEMA6A,ASIC4,SLC2A5,SLCO1A2,DDX25,ATP1A3,FYN,COLGALT2,RGL1,ACSBG1,WSCD1,BRSK2,PTGDR2,PARD6A,LRRC23" Drug 3108_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,AGT,FOXG1,RASA3,GPR153,ALDH1L1,ADGRL3,WWC1,PSD3,GRIN1,TF,TGFBR3,PADI2,MASP1,RIMS3,STMN4,KCNMA1" Drug 3763_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FGF1,AMPH,APBB1,BCAS1,PDE8B,SLCO1C1,ACSBG1,NUMA1,GRIK2,TNS1,PCDH9,PDE2A,SULT4A1,SPATA6,PTCH1,KCNK2,RAD52" Drug 2837_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "NDRG2,SEMA6A,C1orf61,RASA3,APC,SLC1A2,PKNOX2,ATM,WDTC1,GLS,VAMP1,CACNB2,ZMYND8,POU3F4,TENM4,MAPK10,PRDM2" Drug 6315_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "MAPT,TUBB4A,CDC42BPA,TACC2,CGREF1,DLL3,WDTC1,NUCB1,MICAL1,PTPA,ARHGEF4,SMG7,KCNMA1,PEX5,DLG3,PID1,DTNA" Drug 4574_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "FGF1,MSR1,CADM3,MLC1,BTRC,GPR17,USP2,NEURL1,CDC42,CADM1,SPATA6,CTNND2,PHYHIP,SRGAP3,RABGAP1L,PARP11,RGS10" Drug 5097_UP Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,NDRG2,FABP7,KIAA1109,APC,SORBS1,BRINP2,NDUFA5,GPR17,TNS1,PDE2A,CHD5,VCAN,CTNND2,RASGRF1,USH1C,SIDT2" Drug 4497_DN Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "PAQR6,KIAA1109,APBB1,CGREF1,NDUFA5,ASTN2,MYRF,BTRC,PC,VCAN,SIRPA,PTHLH,CNIH3,DTNA,RGS7,PLEKHO1,EPB41L2" Drug 5999_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "WLS,KCNIP2,ADCY2,RYR1,FOXG1,AMPH,MSR1,ASCL1,ALDH1L1,GNG4,CDH10,PDE3B,CRMP1,PRDM2,RASGRF1,PAK5,NUP214" Drug 5536_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "DPF1,CDHR1,ANK1,APBA2,SLC2A5,NCAM1,GNG3,CDH10,HPCA,ZFYVE9,TOX,RIMS3,JAKMIP2,HP1BP3,TMCC2,LPAR6,LRRC23" Drug 825_UP rottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "F3,CDC42BPA,ZNF365,PKNOX2,GPR153,ATP2B2,WDTC1,VAMP1,WSCD1,NUMA1,VAV2,PTHLH,KCNC1,KCNMA1,RAD52,ST8SIA3,EPB41" Drug 3121_DN (1)-Nipecotic acid [498-95-3]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "GRAMD1B,KIAA1109,PLA2G6,CSPG5,WDTC1,ZCCHC24,ZSWIM8,KAZN,CAMSAP2,GPR19,ZMYND8,NMT2,CSF3R,CTNND1,PTAFR,RGS10,VWA5A" Drug 3716_DN Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ASIC1,PAQR6,FGF1,SLN,MLC1,GNG4,NUMA1,PLEKHB1,CHRNB2,PIK3CD,CHD1L,VCAN,CTNND2,KIAA0513,AK5,ATN1,DTNA" Drug 5831_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.20E-03 1.00E+00 3.81E-02 4.18E-01 17 196 "ACTN2,SNAP25,PHLDB1,VAMP1,GNG4,GPR17,VCAN,MAPK8,PTPRE,KCND3,SRGAP3,RAB3IL1,PID1,RAD52,NUP214,RGS7,RGS10" Drug ctd:D016627 Oxidopamine CTD 2.21E-03 1.00E+00 3.81E-02 4.18E-01 15 163 "MAPT,SLC1A2,GAD2,GFAP,ABCC8,GRIA2,GRIN1,AIFM1,TNFRSF1B,PDYN,MAPK8,KCNJ11,ABCC9,RET,EN2" Drug CID000656948 pD 8 Stitch 2.22E-03 1.00E+00 3.81E-02 4.18E-01 5 24 "SEMA6A,GRIA1,GRIA2,GRIA4,PTPN5" Drug CID000002533 calphostin C Stitch 2.26E-03 1.00E+00 3.81E-02 4.18E-01 30 431 "MBP,ADCYAP1R1,ADORA1,AGT,ACTL6B,SLC8A2,SLC8A3,ATP2B2,MLC1,NODAL,NPPA,GRIK2,GRM3,LEFTY2,PDYN,CHRM1,CAMKV,PIK3CD,TJP2,PTPA,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PLPPR5,ITGAV,GOPC,CAMK1G" Drug 3637_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 3.81E-02 4.18E-01 16 180 "KIAA1109,FOXG1,PPM1E,APBA2,PKNOX2,SLC6A9,ASCL1,SOX10,NPAS3,COLGALT2,USP2,PIK3CD,RAD52,DPP6,DTNA,PAK5" Drug 7407_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.29E-03 1.00E+00 3.81E-02 4.18E-01 16 180 "ADD3,TESK2,FYN,ZCCHC24,RGL1,ACSBG1,PCDH9,SERPINE2,DNAJC12,DZIP3,KIAA0513,RIMS3,PTCH1,DNAJC6,ATN1,RASGRP2" Drug 4376_UP Withaferin A [5119-48-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 3.81E-02 4.18E-01 16 180 "TUBB4A,AGT,KIAA1109,CDC42BPA,SLC6A9,CCDC88A,CSPG5,GPM6B,GRIK2,PTGDR2,PIK3CD,NECAB2,CRMP1,AK5,KCNN3,EN2" Drug 6988_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "PAQR6,NDRG2,PLA2G6,FHL1,SYBU,NLGN1,TAGLN3,EMC1,GLS,GNG3,GPM6B,PDE3B,MAPK10,RIMS3,SYNC,NUP214,EFNA3" Drug 6704_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "APC2,CEND1,ADCY2,GAS7,PKNOX2,SLN,NHLH1,BTRC,NEURL1,PDE3B,MASP1,PLPPR4,KCND3,PARP11,ATN1,DSCAM,VWA5A" Drug 3930_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CEND1,MDM4,DNAH17,ZCCHC24,GAD2,ADAM15,KAZN,CACNA1A,HAP1,PSD3,PDE1C,CRMP1,MAPK8,ITIH2,MAGI2,NKAIN1,ATN1" Drug 5792_UP Butamben [94-25-7]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FABP7,NTNG1,BCAS1,ASTN1,ALDH1L1,GFRA1,KAZN,GPM6B,CACNB2,PDE3B,ZMYND8,ARHGAP22,FLRT1,NOS1AP,RABGAP1L,ARNT2,PARP11" Drug 1751_UP Stachydrine hydrochloride; Up 200; 22.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,LGR4,ECSIT,ARID1A,NDRG2,PPFIA1,BCAN,ADAM15,FAM168A,TNS1,ACOT7,ZFYVE9,PTPA,ECE2,DNM2,RAP1GAP,SEC61A2" Drug 4555_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ANK1,RASA3,SLC2A5,ASTN1,TNIK,GAD2,ADGRL3,CHRNB2,CTNND2,MAPK8,PTAFR,MAGI2,RALGDS,RASGRF1,DTNA,ST8SIA3,TTLL7" Drug 1591_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "RABEPK,PAQR6,CDC42BPA,ANK3,ITSN1,BCAN,WDTC1,EMC1,ALDH1L1,RGL1,GNG4,TNS1,COL9A2,RALGDS,CAMK1G,SIDT2,ABI2" Drug 3818_UP U-62066 [87151-85-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "EMID1,AQP4,SLN,B3GAT1,DKK3,OPCML,TPM3,JAM2,CADM1,PRRX1,PLCH2,PROX1,SMG7,KCNC1,AK5,NUP214,EFNA3" Drug 6772_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "NDRG2,GPR153,CADM3,GNAS,NEURL1,KCNK10,TPM3,CHRNB2,ZFYVE9,PIK3CD,CNTN1,CHD5,RIMS3,PTHLH,KCNA1,RGS10,SSPN" Drug 6106_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ACTN2,MOBP,AMPH,RASA3,SLC1A7,SHANK2,SNAP25,NCDN,POPDC3,KAZN,WSCD1,HAP1,NEURL1,ARHGEF4,KCNMA1,DTNA,VWA5A" Drug 2773_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,RYR1,C1orf61,APC,BCAN,ALDH4A1,CADM3,GPM6B,ZEB1,TPM3,ZFYVE9,CNTN1,PRRX1,CRMP1,MAPK8,PTPRE,EFNA3" Drug 3416_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,ARID1A,CDC42BPA,PKP4,ALDH4A1,PHLDB1,AJAP1,POPDC3,ROBO3,CACNB2,NUMA1,TGFBR3,NEURL1,PDE3B,VAV2,MICAL2,SDC3" Drug 2796_DN Bicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CDC42BPA,ITSN1,ZNF365,ALDH4A1,WDTC1,B4GALNT1,BTRC,USP2,ZFYVE9,FEZ1,IGSF1,EDRF1,PEX5,RALGDS,DSCAM,SIDT2,EFNA3" Drug 3698_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FABP7,SLC2A5,TAGLN3,ATP1A3,SOX10,GLS,GRIK2,CRB1,DCLK1,PTGDR2,CHRNB2,PIK3CD,CHD1L,PLCH2,SRGAP3,DTNA,OLIG2" Drug 2522_UP Napelline [5008-52-6]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "KIAA1109,APC,NLGN1,SHANK2,TAGLN3,CCDC181,NCAM1,ALDH1L1,ATF7,NRXN1,NMT2,NCAN,DZIP3,PRKCZ,PROX1,PMEPA1,KCNK1" Drug 1333_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ABAT,ANK3,RASA3,GAD2,FAM168A,ZNF384,PDE3B,BEST1,IFFO1,VCAN,MAPK8,SMG7,PEX5,RAD52,SIDT2,ARHGAP12,LRRC23" Drug 2854_DN Lovastatin [75330-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "F3,FHL1,FOXG1,SCMH1,ZCCHC24,SPART,FAM168A,CAMK2G,PC,UBTF,VAV2,MICAL1,SDC3,JAKMIP2,ATG16L1,RGS10,ARHGEF10L" Drug 5704_UP Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,ACTN2,ASCL1,GPR153,PSD3,PDE1C,PHKG1,ZFYVE9,PIK3CD,SPATA6,SNCAIP,RGS6,MAGI2,SV2A,DSCAM,RASGRF1,DTNA" Drug 6138_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MBP,FOXG1,CDC42BPA,ZSWIM8,RND1,AJAP1,MYRF,HAP1,PCDH9,TPM3,CHRNB2,CAMKV,NCAN,KLK6,PLPPR4,ATN1,RASGRF1" Drug 6389_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "NTNG1,GAS7,BCAS1,PKNOX2,ASCL1,SOX10,ALDH1L1,NCDN,RND1,HAP1,SEZ6L,ADGRG1,CRMP1,MAPK8,PTPRD,RAB3IL1,RGS10" Drug 4391_UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,ACTN2,TUBB4A,PLA2G6,SLC6A9,SORCS3,SNAP25,GAD2,MLC1,NHLH1,NPPA,VCAN,NOS1AP,KCND3,KCNH1,ELAVL4,EPB41" Drug 6015_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "WLS,FHL1,FOXG1,APBA2,BRINP2,POPDC3,ATF7,HAP1,NEURL1,SEZ6L,HPSE2,DUSP26,ZFYVE9,CRMP1,NOS1AP,KCND3,SIDT2" Drug 5565_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,ADCY2,RYR1,MOBP,MSR1,CCDC181,RGL1,GNAS,TCF7L2,PCDH9,PIK3CD,IFFO1,MAPK10,PTPRO,SRGAP3,TMCC2,RASGRP2" Drug 5083_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "PLA2G6,HPCAL4,ANK1,MSR1,CADM3,GAD2,ADGRB2,PHLDB1,GNG4,CACNA1A,BRSK2,PTGDR2,LILRA4,ZMYND8,PID1,FAM13C,ST8SIA3" Drug 3796_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FOXRED2,PKNOX2,ASTN1,SCN3B,KIF21B,CADM3,GPR88,KCNK10,PDE3B,DUSP26,SULT4A1,IFFO1,POU3F2,POU3F4,MAGI2,ATN1,VWA5A" Drug 6204_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "F3,RASA3,ITSN1,GAS7,PKNOX2,CADM3,PHLDB1,GNG4,GPM6B,NEURL1,PDE3B,ZMYND8,MICAL1,RALGDS,ATN1,DSCAM,LRRC23" Drug 5685_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,ADCY2,ADORA1,LRRTM4,PLA2G6,SLC30A10,MOBP,CDC42BPA,SLC2A5,ASCL1,DNAH17,FGF17,GPM6B,NECAB2,CRMP1,ARHGEF4,KCNMA1" Drug 2570_UP Methimazole [60-56-0]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "NDRG2,ADORA3,PKP4,NAP1L2,RAP1GAP2,RND1,VAMP1,BTRC,CAMK2G,PSD3,USP2,ZFYVE9,FLRT1,VCAN,EDRF1,DTNA,EFNA3" Drug 3076_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "C1orf61,CDC42BPA,BCAS1,SLC14A1,ALDH4A1,PALLD,WDTC1,ALDH1L1,POPDC3,WSCD1,HAP1,INA,REPS2,CNTN1,MICAL2,RAD52,DSCAM" Drug 6756_UP Lynestrenol [52-76-6]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ACTN2,SCN3A,PLA2G6,HPCAL4,AQP4,CSPG5,SLCO1A2,B3GAT1,ALDH1L1,GNG3,PRUNE2,HAP1,GRIK3,MED1,VCAN,SMG7,KCND3" Drug 7192_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,PLA2G6,FHL1,CDC42BPA,SYBU,ALDH4A1,EMC1,SPART,GNAS,BTRC,EML4,CDH10,IFFO1,PROX1,PARD6A,RALGDS,ATG16L1" Drug 22_DN 1-phenylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "NDRG2,FGF1,FGR,APBA2,ASCL1,DNAH17,CADM3,NMNAT2,GLS,GRIN1,PDE1C,JAM2,IGSF1,PTCH1,DPP6,SUSD4,SIDT2" Drug 2135_UP Conessine [546-06-5]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ACTN2,ADORA1,FGF1,FOXG1,SLCO1A2,NUMA1,GRIA4,ADAMTS8,ATP13A2,TGFBR3,INA,NMT2,FLRT1,NOS1AP,KLK6,CAMK1G,EEF1A2" Drug 6994_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,PAQR6,SYBU,CCDC88A,CAPRIN2,ASPH,VAMP1,NUMA1,CNTN1,NECAB2,MAPK8,MAPK10,KCNK1,NAV2,RAD52,FAM13C,SIDT2" Drug 5508_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "EMID1,SYNDIG1,EXTL1,MDM4,FHL1,GAS7,ASPH,NPAS3,NCAM1,CDH10,PLEKHB1,FEZ1,SDC3,EDRF1,PRDM2,ATG16L1,DTNA" Drug 5402_UP Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FGF1,ASIC4,HPCAL4,CDC42BPA,RASA3,GAS7,SHANK2,PDE8B,NDUFA5,CAMK2G,GRM3,PDE3B,CHRNB2,MICAL1,RIMS3,ITIH2,LMO1" Drug 2915_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FOXG1,CDC42BPA,ANK3,PDE8B,SORCS3,RAP1GAP2,BTRC,NPPA,INA,TJP1,TPM3,MAGI1,PLEKHB1,ZFYVE9,NRXN1,MICAL2,ST8SIA3" Drug 5747_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "LRRTM4,FOXG1,C1orf61,PKNOX2,NDUFA5,ACSBG1,BTRC,PRUNE2,GPR17,HAP1,PADI2,MICAL2,ITIH2,SRGAP3,ARNT2,RALGDS,ATN1" Drug 2892_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,FOXG1,ALDH4A1,ATM,NDUFA5,DAAM2,TNS1,ADGRG1,ZFYVE9,NMT2,CNTN1,SNCAIP,CNIH3,PEX5,RAVER2,ELAVL3,EN2" Drug 365_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "GAS7,BCAS1,CADM3,WWC1,WSCD1,GRIN1,ATP13A2,TNS1,PCDH9,CDH8,ARHGAP19,TPM3,CHRNB2,MAPK8,KCNJ9,RET,LRRC23" Drug 5768_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "TTYH1,CEND1,FOXRED2,RASA3,APC,GLS,BTRC,GPM6A,NPPA,CACNB2,GPR17,GRIA4,NEURL1,COL9A2,ITIH2,KCNJ4,PID1" Drug 5292_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ARID1A,WAC,APC,CGREF1,EMC1,NCDN,FAM168A,ATP13A2,PMS2,DZIP3,PRKCZ,CTNND1,HP1BP3,PARD6A,DLG3,KIF2A,ARHGEF10L" Drug 2244_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ARID1A,NDRG2,SEMA6A,APC,GPR153,WDTC1,ZCCHC24,GLS,GNG4,HAP1,PSD3,MICAL1,DZIP3,PTHLH,PEX5,DSCAM,SSPN" Drug 4135_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MOBP,SLC2A5,CADM3,NMNAT2,EMC1,RND1,WSCD1,ATF7,CDH10,JAM2,MICAL2,PTAFR,NTM,KCNMA1,RASGRF1,RGS10,SSPN" Drug 5528_UP Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FOXG1,CDC42BPA,APBA2,APC,PKNOX2,PDE8B,SLN,CADM3,GPR162,MLC1,ROBO3,CACNA1A,GUCY1A2,PDE3B,VCAN,MAPK10,EDRF1" Drug 7150_UP "(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,APC,SLC6A9,GAD2,ASTN2,MYRF,CACNB2,ZMYND8,ZFYVE9,VCAN,ARHGEF4,CTNND2,FAM131B,SMG7,RAB3IL1,EFNA3,EN2" Drug 4416_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,ASIC1,KIAA1109,SLC30A10,DOCK10,GAS7,BCAN,SLC1A2,GAD2,CPLX2,RGL1,GLS,CDH8,SULT4A1,CAMK1G,VWA5A,RAVER2" Drug 6018_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "AGT,PLA2G6,CDC42BPA,DNAH17,TAGLN3,CAPRIN2,ATM,PHLDB1,KAZN,ROBO3,BTRC,CAMK2G,NEURL1,PDE3B,RIMS3,RABGAP1L,DTNA" Drug 5563_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CEND1,FGF1,SELL,ST8SIA1,DNAH17,TAGLN3,BRINP2,SNAP25,SPART,GLS,POPDC3,ATF7,HAP1,PDE1C,CAMKV,PHYHIP,ATN1" Drug 2481_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "GRAMD1B,KIAA1109,FHL1,RASA3,CCDC88A,NCAM1,ZEB1,EML4,NUMA1,PADI2,CTNND1,RIMS3,PTAFR,RABGAP1L,DTNA,SIDT2,EFNA3" Drug 7239_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CEND1,ADORA1,KIAA1109,SYBU,WDTC1,ZCCHC24,GAD2,ALDH1L1,PHLDB1,PDE3B,ASIC3,PRRX1,SDC3,MAPK8,EDRF1,SSPN,EFNA3" Drug 2465_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "AGT,ANK3,NLGN1,BCAS1,RPH3A,SLN,NAP1L2,SLCO1C1,CAMSAP2,GPM6A,NPPA,ATP13A2,GUCY1A2,CDH10,TMPRSS5,NTM,RASGRP2" Drug 2196_UP Ethotoin [86-35-1]; Up 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ARID1A,SEMA6A,FOXG1,CDC42BPA,SNAP25,CADM3,ATF7,NPPA,REPS2,TNS1,POU3F2,ARHGEF4,SV2A,NTM,ATN1,ELAVL3,RCAN2" Drug 7052_UP 0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "PAQR6,APC,SHANK2,GPR153,ZSWIM8,B4GALNT1,NCDN,VAMP1,WSCD1,HAP1,CAMK2G,MAGI1,ZMYND8,CHRNB2,NOS1AP,PRDM2,SEC61A2" Drug 3881_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CDHR1,CLIP1,PLA2G6,ITSN1,APBA2,SLC6A9,CSPG5,AJAP1,PRUNE2,OLR1,CDC42,DCLK1,TPM3,CHRNB2,PIK3CD,DTNA,TTLL7" Drug 2445_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "APC2,CEND1,ACTN2,FOXG1,CDC42BPA,ANK3,DNAH17,NPPA,GRIA1,GUCY1A2,CHGA,NECAB2,DZIP3,CTNND1,ZBTB16,CAB39L,NUP214" Drug 5407_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "WLS,FHL1,MOBP,SLC1A7,MSR1,SHANK2,SLC14A1,ZEB1,NEURL1,NECAB2,POU3F2,RIMS3,PTAFR,ITIH2,NKAIN1,RAD52,VWA5A" Drug 5383_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ARID1A,FGF1,PLA2G6,FHL1,FOXG1,APBA2,ATP2B2,SLCO1C1,GNAS,GNG3,CAMK2G,GRIK2,INA,NEURL1,CDC42,PDE3B,ZFYVE9" Drug 5043_UP Piracetam [7491-74-9]; Up 200; 28.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "EMID1,APC,AQP4,PDE8B,SLCO1A2,PHLDB1,GRIN1,USP2,KCNK10,CDH8,CNTN1,RGS6,RIMS3,PHYHIP,ITIH2,STMN4,KCNMA1" Drug 3090_UP Altretamine [654-05-6]; Up 200; 19uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "EYA1,ASIC4,BCAS1,AQP4,CCDC181,NAP1L2,TNS1,HRH3,PDE1C,ZFYVE9,CRMP1,PLCH2,CTNND1,ITIH2,CNIH3,RAB3IL1,EPB41" Drug 6811_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CLIP1,FABP7,TUBB4A,KIAA1109,PLA2G6,ALDH4A1,SPART,RND1,POPDC3,NPPA,ADGRG1,POU3F2,VCAN,RIMS3,KCNH1,RAD52,RBM12" Drug 6714_UP Hesperidin [520-26-3]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "PRR5L,ACTN2,SEMA6A,FOXG1,SLC6A9,SEMA4A,GRIN1,PDE3B,HPCA,ARHGAP22,NRXN2,CTNND2,TOX,KCNC1,SLC6A15,CRTAC1,VWA5A" Drug 6091_UP Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "NDRG2,ADORA3,FHL1,SLC2A5,COLGALT2,RGL1,AJAP1,PRUNE2,TNS1,PCDH9,HRH3,FLRT1,MAPK8,NOS1AP,CA10,KCNH1,LRRC23" Drug 3062_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,ST8SIA1,SLC6A9,ASCL1,B3GAT1,B3GALT2,SOX10,USP2,CHGA,HPCA,PMP2,CHD5,KCNC1,KCNH1,KCNMA1,ST8SIA3,EPB41" Drug 498_UP tetraethylenepentamine pentahydrochloride; Up 200; 100uM; ssMCF7; HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,APC,TAGLN3,ATP1A2,ATF7,GUCY1A1,PDE1C,CADM1,VCAN,DZIP3,KCNJ9,PEX5,SNX27,DSCAM,RASGRF1,RLBP1,LPAR6" Drug 348_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CEND1,ADCY2,TUBB4A,C1orf61,ANK2,FYN,GJB1,CACNA1A,PTBP2,GRIA4,OMG,SEZ6L,PPP3CB,PKN2,ECE2,JAKMIP2,KCND3" Drug 2380_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ABAT,FHL1,HPCAL4,PDE8B,SOX10,NAP1L2,ROBO3,CAMSAP2,TCF7L2,PSD3,USP2,CDH8,CCSER2,POU3F2,POU3F4,CRMP1,SV2A" Drug 2858_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,EMID1,NDRG2,GAS7,MSR1,PDE8B,ATM,GNG4,BTRC,PTBP2,CHRNB2,ZFYVE9,VCAN,PRDM2,TMCC2,ATN1,SIDT2" Drug 3577_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "RYR1,FHL1,APC,SLC2A5,INKA2,RND1,WSCD1,ATF7,GRIN1,ASIC3,PROX1,PLPPR1,CNIH3,NTM,ST8SIA3,LMO1,ELAVL3" Drug 205_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "SEMA6A,C1orf61,SLC2A5,CADM3,GAD2,NAP1L2,SPART,ZNF638,NRGN,NUMA1,GRIN1,SEZ6L,CAMKV,IFFO1,CRMP1,GON4L,DTNA" Drug 4602_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,APC2,RTN1,SELL,SEMA6C,AMPH,ANK1,SLC1A6,ASCL1,SLCO1A2,NPAS3,ST8SIA5,CTNND2,TOX,PRDM2,SMG7,KCND3" Drug 4100_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,FOXRED2,HPCAL4,ANK2,APC,NTNG1,GART,SLCO1C1,GNG4,DDR2,NEURL1,NECAB2,ARHGEF4,MAPK8,SV2A,DSCAM,DTNA" Drug 4620_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "GAS7,SLC8A2,CCDC181,CADM3,ASTN2,TNS1,ST8SIA5,CTNND2,NOS1AP,PTCH1,KCNA2,KCND3,SRGAP3,SUSD4,RASGRF1,ABCC9,ROM1" Drug 3877_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FOXG1,GAS7,SLC2A5,DNAH17,SLN,SNAP25,SPART,KAZN,PRUNE2,CHRNB2,IFFO1,CRMP1,NOS1AP,PTAFR,CNIH3,KCNJ4,TTLL7" Drug 2374_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ANK3,RPH3A,ZCCHC24,NAP1L2,GPR162,KAZN,WSCD1,NUMA1,USP2,PDE1C,CCSER2,FLRT1,RIMS3,PARD6A,NTM,DTNA,LRRC23" Drug 5262_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "SYNDIG1,KIAA1109,C1orf61,SLC2A5,BRINP2,ALDH1L1,POPDC3,ROBO3,ZEB1,CDH10,PDE1C,DNAJC6,TMCC2,PARP11,DTNA,SIDT2,ELAVL3" Drug 2692_UP troglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "EMID1,MOBP,MSR1,ASCL1,CSPG5,SLN,ALDH4A1,PCDH9,CA14,HPCA,NRXN2,VCAN,PTHLH,PARD6A,KCND3,CAB39L,RASGRF1" Drug 3870_DN (S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "C1orf61,CDC42BPA,APC,FYN,WDTC1,RGL1,RND1,GLS,CACNB2,NUMA1,MAPK8,SYNC,PTHLH,PEX5,RAD52,DSCAM,RGS10" Drug 6666_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ACTN2,AGT,FGF1,SEMA6A,SELL,RASA3,NTNG1,SLITRK3,SORBS1,MSR1,PHLDB1,IFFO1,GON4L,MAGI2,SRGAP3,KCNMA1,RASGRF1" Drug 6649_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ACHE,RYR1,AMPH,RASA3,NTNG1,SLC6A9,MYT1L,MYH7,BRSK2,SEZ6L,ADGRG1,IFFO1,ARHGEF4,TOX,RIMS3,KCND3,SRGAP3" Drug 4504_DN Iopromide [73334-07-3]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FGF1,HPCAL4,SLC1A7,ASPH,SLN,MLC1,GNG4,OPCML,MAGI1,ZMYND8,NMT2,CNTN1,MAPK8,PLPPR1,AK5,KCNMA1,PID1" Drug 2122_UP Nifenazone [2139-47-1]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "TUBB4A,RPH3A,WDTC1,PHLDB1,TCF7L2,BRSK2,PSD3,PTGDR2,VAV2,SPATA6,PRDM2,STMN4,SMG7,PEX5,RAD52,RGS10,EN2" Drug 3639_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ADORA1,KIAA1109,SEMA6A,SHANK2,ASTN1,CADM3,SOX10,GAD2,RND1,GNG3,GPM6A,CAMK2G,NUMA1,USP2,CRMP1,PTAFR,SRGAP3" Drug 3555_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ADORA1,APBA2,BCAS1,SLN,ATP1A3,FYN,WDTC1,ALDH1L1,GPR162,RND1,ADAMTS8,PDE1A,TMCC2,DNAH9,ATN1,RASGRF1,EFNA3" Drug 3820_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "DPF1,ADCY2,KIAA1109,FGF1,ATM,ATP1A3,NEUROD1,KAZN,GNAS,ROBO3,GNG3,BTRC,CACNB2,PDE4B,SPATA6,KCNMA1,DNM2" Drug 5641_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "ASIC1,TUBB4A,FGF1,FHL1,MOBP,SHANK2,EMC1,NCAM1,PRUNE2,GPM6B,ZEB1,HAP1,GRIK2,OMG,PCSK2,DSCAM,PAK5" Drug 3996_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MSR1,PKNOX2,B3GAT1,ADGRB2,INKA2,ACSBG1,KAZN,CDK5R2,PHKG1,CABP1,PTAFR,PRDM2,KCNJ9,ARNT2,RASGRF1,SLC6A15,ST8SIA3" Drug 3138_UP Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "CDHR1,ADORA1,CDC42BPA,GPR153,ALDH4A1,CCDC181,PRUNE2,HAP1,GUCY1A2,KCNK10,DAAM2,SEZ6L,ZFYVE9,CAMKV,PEX5,ST8SIA3,TTLL7" Drug 6785_UP "Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "BCAN,SLC2A5,PKNOX2,ALDH4A1,ZCCHC24,BCL2L2,NEUROD1,PSD3,TNS1,CHRNB2,CNTN1,PACSIN1,MICAL2,NOS1AP,RGS10,EFNA3,RAVER2" Drug 4502_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "PRR5L,ARID1A,FGF1,FGF14,FOXG1,ANK1,BCAS1,ATP2B2,CADM3,ALDH1L1,KLHL4,NPPA,GUCY1A2,MICAL2,PTAFR,PTCH1,ROM1" Drug 6776_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MAPT,KIAA1109,SEMA6A,FHL1,APC,GPR153,ZCCHC24,NCDN,ASTN2,GNG4,UBTF,EDRF1,PEX5,DNM2,RAD52,DTNA,ELAVL3" Drug 2698_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "MOBP,ASPH,ATP1A2,NCAM1,GJB1,TCF7L2,PSD3,GUCY1A1,TNS1,CDH10,GPR37L1,CHGA,CHI3L2,SULT4A1,STMN4,KCNA2,KCND3" Drug 2324_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "FHL1,FOXG1,SLN,WDTC1,B4GALNT1,GNG4,TCF7L2,NUMA1,SDC3,CTNND2,EDRF1,KIF2A,ATN1,DTNA,SSPN,VWA5A,ROM1" Drug 3925_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.32E-03 1.00E+00 3.81E-02 4.18E-01 17 197 "APC2,SYNDIG1,AGT,FOXG1,SORBS1,PKNOX2,ATP1A2,ATP1A3,NMNAT2,VAMP1,INA,TNS1,SCRG1,OSBPL3,KCNC1,NTM,ELAVL3" Drug CID000420767 D-TI Stitch 2.35E-03 1.00E+00 3.81E-02 4.18E-01 6 35 "MBP,F3,GAD2,NEUROD1,RND1,ROBO3" Drug ctd:C503753 Indolinone A CTD 2.35E-03 1.00E+00 3.81E-02 4.18E-01 6 35 "MAPT,INA,PDE4B,HNRNPK,PACSIN1,SH3GLB1" Drug CID000006035 bromodeoxyuridine Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 27 376 "MBP,RTKN,FABP7,FGF1,ACTL6B,FOXG1,AQP4,ASCL1,GAD2,NCAM1,GFAP,KIRREL3,GJB1,NEUROD1,NODAL,GRIA1,ZFP91,HNRNPK,POU3F4,MAPK8,MAPK10,NTM,OLIG1,L1CAM,SSPN,ELAVL3,OLIG2" Drug CID000472326 9-butoxynonanoic acid Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "MAG,MBP,MOG,GFAP" Drug CID000003423 FPL 64176 Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "RYR1,FOXM1,APC,CACNB2" Drug CID000160464 Gv-A Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "CCDC88A,GNAS,CCKBR,SULT4A1" Drug CID000018599 Hepamerz Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "SLC1A2,GFAP,ABCC8,GLS" Drug CID000013350 alpha-fluoro-beta-alanine Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "ABAT,ACLY,NUCB1,AIFM1" Drug CID000122071 BW A1433U Stitch 2.38E-03 1.00E+00 3.81E-02 4.18E-01 4 15 "ADAR,ADARB2,ADORA1,ADORA3" Drug ctd:C057416 KT 5720 CTD 2.41E-03 1.00E+00 3.81E-02 4.18E-01 7 47 "FGF1,PLA2G6,SLC1A2,SNAP25,NPPA,GRIN1,CHRM1" Drug CID000011105 neutral red Stitch 2.41E-03 1.00E+00 3.81E-02 4.18E-01 7 47 "ACHE,BCO1,CACNA1A,AIFM1,KCNA1,PCDH15,ELAVL3" Drug 5573_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.42E-03 1.00E+00 3.81E-02 4.18E-01 16 181 "NDRG2,PPM1E,DOCK10,TACC2,SORBS1,ARHGAP5,SLN,SCN3B,NAP1L2,ZEB1,HAP1,ZFYVE9,SF1,PKN2,EDRF1,KLK6" Drug 7453_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.42E-03 1.00E+00 3.81E-02 4.18E-01 16 181 "ADD3,TUBB4A,SORBS1,FYN,ZCCHC24,RGL1,ACSBG1,VAMP1,PCDH9,PIK3CD,DNAJC12,KIAA0513,RIMS3,PTAFR,DNAJC6,EFNA3" Drug 1175_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.42E-03 1.00E+00 3.81E-02 4.18E-01 16 181 "TESK2,PALLD,ZCCHC24,ZSWIM8,RGL1,RND1,CAMSAP2,GPR19,INA,PADI2,NMT2,CCSER2,KIAA0513,RIMS3,DNAJC6,BSCL2" Drug ctd:D011189 Potassium Chloride CTD 2.42E-03 1.00E+00 3.81E-02 4.18E-01 12 117 "MAPT,ACHE,FGF1,SNAP25,ATP1A3,GNAS,CACNA1A,NRXN2,MAPK10,KCNA1,KCNA4,KCNC1" Drug 6037_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MOBP,ANK2,DOCK10,NTNG1,SLC1A7,WDTC1,INKA2,SEMA4A,PRUNE2,WSCD1,GPM6B,ZEB1,HPSE2,SULT4A1,SNCAIP,KCNJ9,ATN1" Drug 5885_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SHANK2,CGREF1,TAGLN3,EIF4G3,FYN,FAM168A,ARHGEF7,TCF7L2,CADM1,KIAA1549L,RABGAP1L,KIF2A,PID1,RAP1GAP,SEC61A2,EFNA3,RBM12" Drug 6515_DN Trapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CDC42BPA,NLGN1,BCAS1,PDE8B,DNAH17,ALDH4A1,ATM,NUCB1,CDH8,IGSF1,WIPF2,RAB3IL1,RAB5B,DSCAM,ZNF248,SSPN,SIDT2" Drug 4798_DN Propantheline bromide [50-34-0]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,C1orf61,ITSN1,SYBU,ZCCHC24,GLS,CACNB2,PDE3B,PIK3CD,VAV2,PACSIN1,GON4L,SYNC,SMG7,RGS10,SSPN,EPB41L2" Drug 2259_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,APC2,NLGN4X,KIAA1109,DOCK10,APC,DLL3,SNAP25,ATM,ZEB1,SEZ6L,CRMP1,PTAFR,PTHLH,KCNMA1,TTLL7,SSPN" Drug 5487_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ACTN2,FOXRED2,BCL2L2,PHLDB1,GNG4,PDE3B,PDE4B,ZFYVE9,CHD1L,SMG7,PARD6A,RABGAP1L,ATN1,SEC61A2,SSPN,SIDT2,PLEKHO1" Drug 3859_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CEND1,NDRG2,KIAA1109,C1orf61,INKA2,POPDC3,OMG,PDE3B,ADGRG1,CNTN1,VCAN,PTAFR,TMCC2,KCNMA1,DNAH9,DTNA,EPB41" Drug 2206_UP Finasteride [98319-26-7]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "PLA2G6,MOBP,SHANK2,PDE8B,SLN,PALLD,TNIK,ALDH1L1,GPR162,PHLDB1,BTRC,NPPA,ATP13A2,ZFYVE9,EDRF1,SYNC,DSCAM" Drug 6160_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CEND1,MSR1,PALLD,PHLDB1,FAM168A,ATP13A2,SPX,CHRNB2,DUSP26,DZIP3,MASP1,PTAFR,CNIH3,PLPPR4,DTNA,NUP214,RASGRP2" Drug 1507_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KIAA1109,ITSN1,APC,BCAN,PHLDB1,SLCO1C1,GPM6A,GRIK2,TGFBR3,NMT2,VAV2,MAPK10,NOS1AP,ELMO1,KCNMA1,SEC61A2,EN2" Drug 3012_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ABAT,MAPT,ATP2B2,MYBPC1,ZCCHC24,CADM3,RAP1GAP2,NCDN,GNAS,WSCD1,TCF7L2,CDC42,PADI2,PHKG1,CHD5,PTCH1,RASGRP2" Drug 2340_UP Ofloxacin [82419-36-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ABAT,PLA2G6,CCDC88A,CCDC181,GAD2,KAZN,PSD3,GRIN1,INA,TNS1,CNTN1,PPP2R5C,FEZ1,CTNND1,SMG7,RAD52,RALGDS" Drug 2400_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CEND1,SLC30A10,ZNF365,SLC1A7,PHLDB1,GLS,TGFBR3,MAGI1,PDE3B,CAMKV,PACSIN1,CHD5,MAPK8,DNAJC6,DLG3,EFNA3,LRRC23" Drug 5915_DN rotenone; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SEMA6A,SLC2A5,ASCL1,BRINP2,B4GALNT1,AJAP1,GLS,HAP1,TGFBR3,TNS1,PLEKHB1,RIMS3,GON4L,PTAFR,RABGAP1L,KCNMA1,BSDC1" Drug 7488_UP ST021200; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SLC1A7,CCDC88A,SHANK2,NCAM1,ALDH1L1,HAP1,TIE1,PTGDR2,FADS2,IFFO1,CHD5,MAPK8,ITIH2,HP1BP3,PTPRD,SSPN,VWA5A" Drug 6759_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "PLA2G6,SLC1A7,SLCO1A2,ZSWIM8,ALDH1L1,KAZN,MYRF,PRUNE2,HAP1,P2RX7,TNS1,ZMYND8,FAM131B,KIAA0513,SRGAP3,DTNA,ST8SIA3" Drug 3022_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,ARID1A,ANK3,SLC1A7,ASPH,SNAP25,NEUROD1,ACSBG1,PRUNE2,WSCD1,CAMK2G,NUMA1,CHGA,ZFYVE9,VAV2,CTNND1,RASGRP2" Drug 3426_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,CDC42BPA,RASA3,APC,ALDH4A1,ZCCHC24,ALDH1L1,MLC1,WSCD1,GPR19,NUMA1,NMT2,SULT4A1,MICAL1,NOS1AP,CNIH3,SSPN" Drug 3505_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ITSN1,CCDC88A,ATM,CADM3,GLS,MYRF,PSD3,GUCY1A2,PCDH9,PACSIN1,IFFO1,EDRF1,JAKMIP2,PLPPR4,TMCC2,FAM13C,SSPN" Drug 2874_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,EMID1,ARID1A,FGF1,CDC42BPA,GAS7,MSR1,SLN,ALDH4A1,RND1,ATF7,CACNB2,GRM3,SERPINE2,TMCC2,DNAH9,ATN1" Drug 2727_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,ADORA1,HPCAL4,RPH3A,PKNOX2,CSPG5,DDX25,ALDH4A1,CCDC181,ASTN2,BTRC,PCSK2,PDE1C,HPSE2,BEST1,KCND3,NUP214" Drug 2327_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ADCY2,TUBB4A,APC,SLC1A2,ASPH,CADM3,BTRC,PSD3,OPCML,GUCY1A2,SERPINE2,FADS2,OSBPL3,MAPK10,PTPRO,RAB3IL1,DSCAM" Drug 3929_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAG,MBP,ADORA1,ADORA3,FHL1,SLITRK3,PKNOX2,SHANK2,SLCO1A2,WDTC1,CADM3,ABCC8,MICAL1,VCAN,NOS1AP,KCNC1,ST8SIA3" Drug 2349_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "GPR153,DLL3,ALDH4A1,GJB1,VAMP1,CAMK2G,PSD3,OMG,PPP2R5C,FEZ1,VCAN,SMG7,TMCC2,RALGDS,DTNA,RET,SIDT2" Drug 3023_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ACTN2,ANK3,CCDC88A,TAGLN3,ZCCHC24,ADAM15,NCAM1,GNG3,GNG4,TCF7L2,PADI2,ZFYVE9,CHD5,PRKCZ,ARHGEF4,PTCH1,RAD52" Drug 1712_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MBP,CEND1,BCAN,SLC1A7,PDE8B,ADGRB2,ALDH1L1,GJB1,PHLDB1,CACNA1A,OMG,CDH10,LILRA4,ZMYND8,DUSP26,PACSIN1,TMCC2" Drug 401_DN LY294002; Down 200; 10uM; ssMCF7; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,RBM10,FOXRED2,ITSN1,APBA2,BRINP2,SNCB,ZCCHC24,EMC1,GPR19,NRGN,TNS1,ARHGAP19,IFFO1,BRINP3,NKAIN1,L1CAM" Drug 2541_DN Propidium iodide [25535-16-4]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "TESK2,FHL1,SLC1A7,VAMP1,CACNA1A,NUMA1,GRIK2,ATP13A2,REPS2,TPM3,ZFYVE9,KCNMA1,RAB3IL1,RALGDS,FAM13C,EEF1A2,RASGRP2" Drug 4130_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CDC42BPA,RASA3,SHANK2,B3GAT1,ATP1A2,NMNAT2,ALDH1L1,SEMA4A,GOLGB1,OMG,ACOT7,PACSIN1,PTAFR,TMCC2,RAD52,RGS10,SIDT2" Drug 4529_UP Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,FOXRED2,SCN3A,GAS7,SORBS1,ASCL1,DNAH17,NCAM1,ALDH1L1,ACSBG1,GNG3,PRUNE2,PTGDR2,CHI3L2,DNAJC6,DTNA,RGS7" Drug 3381_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EMID1,FOXG1,SELL,ATP1A3,MLC1,ABCC8,POPDC3,ROBO3,GNG3,WSCD1,CHRM4,IFFO1,PTAFR,SRGAP3,KCNMA1,RAD52,NUP214" Drug 6323_UP Cefoperazone dihydrate; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,TESK2,HPCAL4,FOXG1,CCDC88A,MLC1,BTRC,NUMA1,TNS1,PTGDR2,CCSER2,IFFO1,CRMP1,PTPRD,RAB3IL1,ATG16L1,EFNA3" Drug 5096_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KIAA1109,GAS7,SORBS1,BRINP2,ALDH4A1,ATP2B2,ASTN2,GRM3,DAAM2,TNS1,PTGDR2,ADGRG1,NRXN2,CABP1,MICAL1,CRMP1,MICAL2" Drug 2650_UP Androsterone [53-41-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EXTL1,PLA2G6,BCO1,ALDH4A1,WDTC1,ZCCHC24,NPAS3,BCL2L2,RND1,GPM6B,TCF7L2,TNS1,MAPK8,NOS1AP,PTAFR,NKAIN1,LMO1" Drug 4751_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,EMID1,EXTL1,RYR1,APBA2,SLN,CADM3,CDH8,ASIC3,POU3F2,CRMP1,PRDM2,KCNH1,NKAIN1,USH1C,RGS10,RCAN2" Drug 3072_DN Rolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "PLA2G6,PKP4,APC,SLC1A7,MSRA,WDTC1,KAZN,MYRF,BTRC,ADGRL3,NUMA1,TPM3,ACOT7,PLPPR1,BEND5,DTNA,RASGRP2" Drug 3110_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,SYNDIG1,RYR1,FOXRED2,MSR1,PALLD,AJAP1,ATP13A2,TJP1,TLL2,CDH10,CHRNB2,ZFYVE9,PTCH1,KCNJ4,ATN1,LRRC23" Drug 3626_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CEND1,MDM4,GAS7,BCO1,WDTC1,EMC1,INKA2,RGL1,NEURL1,CDH10,PDE3B,ZMYND8,SERPINE2,FADS2,CNTN1,RALGDS,VWA5A" Drug 4841_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,NDRG2,AMPH,ANK1,SLC6A9,CCDC88A,TAGLN3,DDX25,CADM3,INKA2,NEURL1,CDH8,PDE1C,VAV2,IFFO1,NOS1AP,ITIH2" Drug 6698_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MDM4,APC,BCAS1,PKNOX2,TNIK,ZSWIM8,EMC1,NEUROD1,RND1,BTRC,BRSK2,OMG,CTNND2,SRGAP3,CAMK1G,EPB41,RASGRP2" Drug 7224_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "RYR1,ALDH4A1,CCDC181,WDTC1,GFAP,RGL1,PHLDB1,RND1,BRSK2,USP2,CDC42,NECAB2,CHD5,TOX,JAKMIP2,CRTAC1,SSPN" Drug 3332_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ARID1A,CLIP1,BCAR3,CDC42BPA,GPR153,NCDN,SEMA4A,CAMK2G,NUMA1,PLEKHB1,ZFYVE9,BRINP3,WBP1L,LRP8,KCNK1,RAB5B,ATN1" Drug 7475_UP Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MDM4,ADORA1,FOXG1,C1orf61,ASTN2,GNAS,BTRC,CACNA1A,HAP1,NUMA1,CDH10,TPM3,PDE1C,PTCH1,DTNA,ROM1,EN2" Drug 3341_UP Reserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ARID1A,NDRG2,F3,KIAA1109,FHL1,NTNG1,GAS7,SORBS1,BCO1,DNAH17,SOX10,RND1,WSCD1,OMG,CDH10,PACSIN1,RAD52" Drug 5473_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "PRR5L,CDHR1,NDRG2,NLGN1,SOX10,INKA2,BTRC,CACNB2,ZMYND8,DUSP26,SULT4A1,PRDM2,HP1BP3,KCNC1,KCNMA1,NAV2,EFNA3" Drug CID000449606 AC1L9NAZ Stitch 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,ADCYAP1R1,ADORA1,ADORA3,GFAP,NELL1,CNTN2,ANO4,TCF7L2,CCKBR,HRH3,TPM3,ANO5,CHRM1,P2RY12,DLG3,EPB41" Drug 3610_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MDM4,NDRG2,KIAA1109,GAS7,ZCCHC24,EMC1,ADAM15,TCF7L2,GPR19,NUMA1,TGFBR3,FADS2,PTHLH,KCNMA1,RAD52,EFNA3,EPB41L2" Drug 2701_UP "estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,ACTN2,FHL1,PKP4,RPH3A,CSPG5,SLCO1A2,TAGLN3,GAD2,TCF7L2,KCNK10,HPSE2,CNTN1,DZIP3,SMG7,KCND3,KCNK1" Drug 2797_UP Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ADORA1,FGR,SLC2A5,PKNOX2,PDE8B,GPR153,SLCO1A2,TAGLN3,DLL3,EMC1,WSCD1,CHI3L2,CHRNB2,MICAL1,MASP1,PLPPR1,PTHLH" Drug 2945_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "RPH3A,SHANK2,PDE8B,WDTC1,ALDH1L1,TCF7L2,GPR19,HAP1,PADI2,TNS1,PCDH9,RBFOX2,FLRT1,NECAB2,KCND3,SEC61A2,LRRC23" Drug 3788_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EXTL1,ADORA3,ANK1,APBB1,APC,ADGRB2,CACNA1A,PRUNE2,GPM6A,GUCY1A2,SLC22A6,POU3F2,PROX1,KCNJ4,SIDT2,VWA5A,ELAVL3" Drug 5047_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,ADCY2,FGF1,PLA2G6,APC,PHLDB1,GNG3,ADGRG1,CA14,KIAA1549L,NMT2,FAM131B,PID1,RAD52,ABCC9,RGS10,SIDT2" Drug 2274_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SCNN1D,GAS7,SLC2A5,NPAS3,PHLDB1,ZEB1,PSD3,GRIN1,CDC42,PTGDR2,PCSK2,ASIC3,PTAFR,PTCH1,PLPPR1,MAGI2,ELAVL4" Drug 4594_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KIAA1109,MOBP,APC,SLC6A9,DNAH17,ALDH4A1,NEUROD1,ACSBG1,GNG4,P2RX7,TPM3,CHRNB2,CTNND2,MAPK8,PLPPR4,RAB3IL1,VWA5A" Drug 2158_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,SLC1A7,SLC2A5,ALDH4A1,PALLD,ALDH1L1,CAMSAP2,GPR19,OPCML,PADI2,TNS1,TPM3,NMT2,BEST1,ETNPPL,SUSD4,L1CAM" Drug 5102_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,CEND1,FOXRED2,HPCAL4,APC,GAS7,DNAH17,NDUFA5,CACNB2,GPR19,TMPRSS5,NSD2,MICAL2,VCAN,SYTL2,ITIH2,DTNA" Drug 5644_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,C1orf61,ATP1A2,GART,AJAP1,ZEB1,NUMA1,PSD3,GRIA1,PHKG1,CAMKV,CHD5,DZIP3,ARHGEF4,PTCH1,KCNK2,EN2" Drug 2228_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC4,C1orf61,GAS7,RPH3A,TAGLN3,DLL3,CPLX2,ADGRB2,NPAS3,RND1,POPDC3,ADGRG1,SULT4A1,CNTN1,PTAFR,ITIH2,DLG3" Drug 5425_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EMID1,HPCAL4,FOXG1,ST8SIA1,GPR153,CADM3,ACSBG1,POPDC3,HAP1,CAMK2G,PCSK2,ARHGEF4,SMG7,NTM,KCNMA1,ATN1,RCAN2" Drug 3016_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,ACTN2,CDC42BPA,NLGN1,WDTC1,SPART,GNAS,TCF7L2,NUMA1,OLR1,PADI2,ZMYND8,ST8SIA5,RAD52,RALGDS,EEF1A2,VWA5A" Drug 5272_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,PLA2G6,APBA2,APC,ZCCHC24,ADAM15,GLS,SEMA4A,GNG4,PLEKHB1,MED1,NOS1AP,PLPPR1,SMG7,PEX5,DSCAM,SSPN" Drug 4074_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,TMEM156,ITSN1,EMC1,NASP,VAMP1,KAZN,ZEB1,NUMA1,TNS1,NMT2,VCAN,RBPJ,ATN1,RGS7,EFNA3,PLEKHO1" Drug 6467_UP Altretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASCL1,BRINP2,B3GAT1,ZCCHC24,SLCO1C1,BTRC,WSCD1,NUMA1,OPCML,PTGDR2,PDE3B,CAMKV,FADS2,NSD2,KCNMA1,SLC6A15,ST8SIA3" Drug 2623_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KIAA1109,AMPH,APBA2,GAS7,SHANK2,GPR153,ASPH,GLS,KCNK10,ADGRG1,FADS2,VAV2,PTHLH,NUP214,RGS10,ELAVL4,RASGRP2" Drug 3359_UP Nadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,FHL1,RASA3,BCO1,ASTN1,FYN,RND1,KCNK10,PTGDR2,SEZ6L,PIK3CD,PLCH2,PEX5,ATN1,DTNA,NUP214,LRRC23" Drug 6496_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,KLRC4,FABP7,HPCAL4,PKNOX2,SORCS3,NPAS3,NEUROD1,WSCD1,GPR37L1,NSD2,VCAN,NOS1AP,HP1BP3,SRGAP3,ATG16L1,DTNA" Drug 7190_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,PLA2G6,SYBU,TAGLN3,DLL3,ALDH4A1,ATM,VAMP1,SEMA4A,CAMK2G,SEZ6L,PDE3B,NMT2,FEZ1,EDRF1,RGR,EFNA3" Drug 6499_UP Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "PLA2G6,SEMA6A,APBA2,AQP4,ATP2B2,MYH7,GPR88,PTGDR2,PCSK2,ZFYVE9,PROX1,ITIH2,ELMO1,RAB3IL1,ATG16L1,ATN1,DTNA" Drug 3970_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,RASA3,PKNOX2,TAGLN3,CADM3,ZSWIM8,NMNAT2,HAP1,GUCY1A2,GPR37L1,RIMS3,PTAFR,KCNC1,SV2A,RAD52,DPP6,ST8SIA3" Drug 3026_DN Ioversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ECSIT,ARID1A,CLIP1,BCAR3,RASA3,PKP4,ASPH,NCDN,CACNA1A,TCF7L2,CAMK2G,RBFOX2,NMT2,DTNA,RGS10,EEF1A2,ABI2" Drug 317_UP N-phenylanthranilic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CDC42BPA,ITSN1,APBA2,RPH3A,NMNAT2,ALDH1L1,TCF7L2,DDR2,OPCML,REPS2,CHRM4,CAMKV,CP,PPP2R5C,OSBPL3,AK5,SIDT2" Drug 5638_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "FHL1,PDE8B,GPR153,ROBO3,GNG3,GNG4,TCF7L2,TPD52,CHRNB2,PIK3CD,SULT4A1,SDC3,PLPPR1,ITIH2,RABGAP1L,KCNMA1,ATG16L1" Drug 6144_DN Piretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,FHL1,APC,NDUFA5,ARHGEF7,ADGRL3,TGFBR3,CDC42,PDE4B,SERPINE2,ZFYVE9,CCSER2,CRMP1,CTNND1,MAPK8,ITIH2,RAD52" Drug 3540_DN Quinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,ARID1A,F3,PDE8B,WDTC1,PHLDB1,ASTN2,ZEB1,CAMK2G,NUCB1,PSD3,OPCML,MICAL1,RIMS3,RALGDS,EN2,LRRC23" Drug 3673_UP Ofloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,ACTN2,NDRG2,B3GAT1,SCN3B,CPLX2,AJAP1,GRIA4,NEURL1,JAM2,SULT4A1,IFFO1,POU3F4,NCAN,PTPRO,ATN1,ABCC9" Drug 169_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MBP,GRAMD1B,ADORA3,FOXRED2,KIAA1109,BCAS1,ASCL1,SON,GLS,MYRF,OMG,CHRNB2,CADM1,RASGRF1,L1CAM,ARHGEF10L,RLBP1" Drug 4690_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "GAS7,SYBU,ATM,PHLDB1,WSCD1,CAMK2G,PDE3B,ZMYND8,HPCA,ATRNL1,MAPK10,ITIH2,KCNMA1,PARP11,SSPN,ROM1,EN2" Drug 6455_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KIAA1109,SEMA6A,COLGALT2,NDUFA5,POPDC3,GPM6B,PAX6,PRMT8,CHI3L2,DUSP26,PHKG1,FLRT1,NSD2,PTCH1,KCND3,KCNMA1,LRRC23" Drug 3802_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "BRINP2,SNAP25,CADM3,SOX10,ADGRB2,LMO3,SLCO1C1,ACSBG1,MYRF,TMEM151B,TNFRSF1B,PDE2A,JAM2,POU3F4,PTAFR,DTNA,VWA5A" Drug 3695_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "CEND1,ASIC4,HPCAL4,SLITRK3,BCAS1,ATP2B2,TNIK,ALDH1L1,MLC1,KAZN,GRIA4,TNS1,SLC22A6,MAPK8,EDRF1,RALGDS,SUSD4" Drug 4095_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "KCNIP2,FGF1,NLGN1,SLCO1A2,KLHL4,GPR17,OLR1,CCKBR,GUCY1A2,HPSE2,CADM1,CNTN1,PMP2,SPATA6,ARHGEF4,MAPK10,DTNA" Drug 6792_UP Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,CEND1,RYR1,PLA2G6,FHL1,HPCAL4,MOBP,CCDC88A,ALDH4A1,ATP2B2,ACSBG1,WSCD1,CACNB2,NEURL1,CDC42,PDE1C,TMCC2" Drug 4638_DN Dioxybenzone [131-53-3]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,SLC1A7,PDE8B,SLN,ATP1A3,NEUROD1,GPR17,OPCML,REPS2,TNS1,CDH10,CHI3L2,PTPRE,PID1,ATN1,L1CAM,RGS10" Drug 2373_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ADORA1,ANK3,TAGLN3,ASPH,ATP2B2,ZSWIM8,ALDH1L1,NPPA,TCF7L2,ZMYND8,NRXN1,PRKCZ,ST8SIA3,EEF1A2,EFNA3,LMO1,LPAR6" Drug 3738_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,FGF1,C1orf61,APC,ADGRB2,PHLDB1,PIK3CD,CNTN1,MAPK8,CNIH3,SMG7,AK5,ATN1,RGS10,RBM12,VWA5A,ELAVL3" Drug 2_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "FOXRED2,FGR,FHL1,APC,PDE8B,SLN,WDTC1,LMO3,KAZN,GRIA4,OPCML,CCKBR,PADI2,TNS1,SEZ6L,CHRM4,FADS2" Drug 4395_UP Cyanocobalamin [68-19-9]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "DPF1,NDRG2,APBA2,SLC1A2,SLCO1A2,FYN,MLC1,TNS1,HRH3,SLC22A6,FLRT1,VCAN,PRDM2,KCNJ4,RAD52,TTLL7,VWA5A" Drug 266_DN (+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EYA1,MOBP,ANK2,ATM,CADM3,NMNAT2,CAMK2A,GRIN1,SEZ6L,SULT4A1,CHD5,ARHGEF4,MASP1,C1orf109,RASGRF1,LPAR6,ELAVL4" Drug 2806_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,ACTN2,F3,PLA2G6,RASA3,RPH3A,PKNOX2,INKA2,SEMA4A,KCNK10,PDE1C,SNCAIP,SYNC,RAB3IL1,RAD52,DTNA,RGS10" Drug 4964_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "EXTL1,RYR1,MOBP,APBA2,SLC1A7,DNAH17,GAD2,ALDH1L1,FGF17,WSCD1,CDH8,SPATA6,MICAL2,OSBPL3,MAPK10,PTHLH,LRRC23" Drug 6202_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ACTN2,ARID1A,FHL1,MOBP,C1orf61,CDC42BPA,TNIK,GPR162,NPPA,ATP13A2,SEZ6L,PLPPR4,TMCC2,KCNK1,RASGRF1,NUP214,ELAVL3" Drug 3005_UP Suprofen [40828-46-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ABAT,ACHE,MBP,SEMA6A,CDC42BPA,AQP4,MSR1,SHANK2,GAD2,ROBO3,TGFBR3,PCDH9,PTGDR2,RGS6,PRDM2,SLC6A15,ST8SIA3" Drug 3736_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "FOXRED2,ATP1A3,ADGRB2,COLGALT2,ALDH1L1,GPM6A,NUMA1,DAAM2,PLEKHB1,MICAL2,MAPK8,PTAFR,PTCH1,PLPPR1,SRGAP3,DTNA,LRRC23" Drug 2772_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,CLIP1,SEMA6A,ASIC4,C1orf61,APC,SLC1A7,PKNOX2,GAD2,CDC42,ZFYVE9,FADS2,CNTN1,PTPA,TMCC2,RAB5B,ROM1" Drug 2715_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,CDC42BPA,BCO1,CPLX2,PHLDB1,PSD3,TGFBR3,PRMT8,POU3F4,EDRF1,RIMS3,CNIH3,DLG3,SLC17A6,TTLL7,EFNA3,OLIG2" Drug 7505_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "NDRG2,CDC42BPA,SLC1A2,SLN,ALDH4A1,ZCCHC24,TCF7L2,EML4,NUCB1,CDH10,CCSER2,FADS2,PACSIN1,NSD2,ATN1,DTNA,EFNA3" Drug 6088_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,ADORA3,PLA2G6,NTNG1,DDX25,FYN,PRUNE2,GPM6A,DAAM2,PDE1C,GPR37L1,TMPRSS5,SULT4A1,PTAFR,CA10,KCND3,ROM1" Drug 4992_DN Progesterone [57-83-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "FOXRED2,URGCP,GPR153,ASPH,GART,SPART,NUMA1,RBPJ,DZIP3,RIMS3,HP1BP3,PARD6A,RABGAP1L,RALGDS,DTNA,NUP214,RGS10" Drug 3801_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "MAPT,ADCY2,FGF1,RASA3,NLGN1,RPH3A,SHANK2,COLGALT2,KAZN,NUMA1,CDC42,TNS1,VAV2,ITIH2,RAD52,ATN1,PLEKHO1" Drug 4976_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "C1orf61,APC,CGREF1,SEMA4A,GNG3,CAMK2G,UBTF,MED1,SDC3,ARHGEF4,IGSF1,PRDM2,RAD52,NUP214,EFNA3,VWA5A,ROM1" Drug 4783_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "FHL1,PKNOX2,TAGLN3,ATM,FGF17,WSCD1,GPM6A,GPM6B,NPPA,TGFBR3,GUCY1A2,ETNPPL,ITIH2,KCND3,KCNMA1,VWA5A,ROM1" Drug 2286_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "APC2,GAS7,PKNOX2,ASTN1,SNAP25,EMC1,ADGRB2,NPAS3,NEUROD1,RND1,SEZ6L,ZFYVE9,NECAB2,CRMP1,PTAFR,PLPPR1,TMCC2" Drug 2281_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "SYNDIG1,EXTL1,SLC1A7,BRINP2,SNAP25,AJAP1,PRUNE2,GPM6A,HAP1,BRSK2,TLL2,DAAM2,PRMT8,CHD5,PTAFR,PTHLH,ATN1" Drug 3292_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,WLS,SEMA6A,C1orf61,GPR153,SLN,B4GALNT1,BTRC,TCF7L2,HAP1,NUMA1,PDE3B,MED1,SF1,PTHLH,RABGAP1L,ROM1" Drug 4675_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ADCY2,APBB1,GAS7,MSR1,WDTC1,CADM3,ADGRB2,BCL2L2,PHLDB1,BTRC,NUMA1,SEZ6L,NSD2,PLPPR4,AK5,KCNJ4,RASGRP2" Drug 4348_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ASIC1,MDM4,APBA2,APC,ATM,WDTC1,RND1,ARHGEF7,GNG4,WSCD1,TCF7L2,ZEB1,CHRNB2,SMG7,RABGAP1L,ATG16L1,LRRC23" Drug 6347_UP Isradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ACTN2,AGT,FGF1,FOXG1,ITSN1,SLC1A7,SLCO1A2,TNS1,DUSP26,CCSER2,IFFO1,SMG7,KCNMA1,ATN1,RASGRF1,SIDT2,PLEKHO1" Drug 2637_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "APC2,SYNDIG1,AGT,GPR153,WDTC1,KIF21B,SOX10,GAD2,HAP1,RBFOX2,CHRNB2,PACSIN1,VCAN,PROX1,TMCC2,FAM13C,RGS10" Drug 6089_UP Althiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "TUBB4A,NLGN4X,SEMA6A,MSR1,SLN,SOX10,PHLDB1,PRUNE2,ATF7,IFFO1,SNCAIP,MAPK8,SRGAP3,KCNMA1,USH1C,RCAN2,LRRC23" Drug 6485_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.45E-03 1.00E+00 3.81E-02 4.18E-01 17 198 "ACTN2,TUBB4A,ASCL1,B3GAT1,NDUFA5,FGF17,GLS,WSCD1,NEURL1,TENM4,VCAN,HP1BP3,SRGAP3,KCNK2,SSPN,VWA5A,RASGRP2" Drug ctd:C060229 "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione" CTD 2.48E-03 1.00E+00 3.86E-02 4.23E-01 8 60 "AGT,GFAP,GNAS,CACNA1E,NPPA,CAMK2A,CHRM1,MAPK8" Drug CID000137518 trifluoro-methyl Stitch 2.48E-03 1.00E+00 3.86E-02 4.23E-01 8 60 "MAG,ABAT,ACHE,F3,PLA2G6,GRM3,PMP2,KCNH1" Drug CID000002215 NSC755875 Stitch 2.49E-03 1.00E+00 3.87E-02 4.24E-01 15 165 "ABAT,ADCY2,BCO1,SOX10,GAD2,GFAP,CACNA1E,NUCB1,CCKBR,PDYN,CHRM1,CHRNB2,CALY,DTNA,EEF1A2" Drug ctd:C043680 ptaquiloside CTD 2.50E-03 1.00E+00 3.87E-02 4.25E-01 13 133 "ADGRV1,ADORA3,NCAM1,TIE1,CDH8,NRXN1,FAT3,PROX1,ITGAV,SV2A,PCDH15,RET,OLIG2" Drug 6316_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.56E-03 1.00E+00 3.87E-02 4.25E-01 16 182 "ABAT,MAPT,BRINP2,FYN,TNIK,ZCCHC24,RGL1,GLS,USP2,PCDH9,DNAJC12,PTCH1,DNAJC6,JAKMIP2,PLPPR4,EFNA3" Drug 3887_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.56E-03 1.00E+00 3.87E-02 4.25E-01 16 182 "ARID1A,WAC,CHST15,TACC2,SON,ARHGEF7,CAMSAP2,TCF7L2,ZMYND8,ZBED5,CCSER2,PUM1,BRINP3,PRDM2,KIF2A,ARHGAP12" Drug 6342_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ARID1A,NDRG2,FOXG1,PKNOX2,SHANK2,ALDH4A1,GAD2,ACSBG1,VAMP1,NUMA1,CHRNB2,CABP1,COL9A2,MAPK8,MASP1,SIDT2,EFNA3" Drug 2986_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ABAT,MAPT,SYNDIG1,NDRG2,C1orf61,RASA3,SNAP25,GNG4,CAMSAP2,RBFOX2,ZFYVE9,PTCH1,SMG7,SV2A,RALGDS,SIDT2,LRRC23" Drug 6794_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "AGT,FHL1,NLGN1,SLC1A7,GPR153,BCL2L2,WSCD1,HAP1,NUMA1,CHRNB2,PIK3CD,PTAFR,JAKMIP2,CNIH3,PARD6A,ATN1,SIDT2" Drug 6634_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FGF1,MOBP,FOXG1,GAS7,ASTN1,TNIK,PCDH9,PTGDR2,HRH3,SEZ6L,TPM3,PROX1,MASP1,ITIH2,SMG7,ATN1,VWA5A" Drug 2495_UP Ethionamide [536-33-4]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "AMPH,PKP4,TAGLN3,DLL3,PALLD,NAP1L2,INKA2,PHLDB1,KAZN,DZIP3,ARHGEF4,PHYHIP,PLPPR4,DLG3,TTLL7,SSPN,RASGRP2" Drug 5959_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FGF1,PLA2G6,RASA3,SLC6A9,ALDH4A1,ADGRB2,VAMP1,ASTN2,GPR19,ZMYND8,IFFO1,CTNND2,PTAFR,RAP1GAP,DSCAM,BEND5,ROM1" Drug 1_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ITSN1,APC,CAPRIN2,CADM3,GAD2,GNG4,PRUNE2,CAMK2A,TMEM151B,CRMP1,VCAN,GON4L,PEX5,DPP6,GNE,RLBP1,LMO1" Drug 2298_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "RYR1,SLC1A7,MSR1,PKNOX2,GLS,CACNA1A,WSCD1,OLR1,P2RX7,TNS1,PTGDR2,VCAN,JAKMIP2,ITIH2,KCNA2,KCND3,TMCC2" Drug 3750_UP Deltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "EMID1,CEND1,MDM4,ASIC4,PKP4,GAS7,ASCL1,PDE8B,NEUROD1,PRUNE2,NUMA1,GRIK2,PDE3B,SULT4A1,IFFO1,PHYHIP,RASGRP2" Drug 4749_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,FHL1,FOXG1,AMPH,CSPG5,DNAH17,GAD2,INKA2,VAMP1,POPDC3,PHKG1,SYNC,PTAFR,NTM,KCNMA1,RAD52,ELAVL3" Drug 3036_UP Aminophylline [317-34-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "CDC42BPA,B3GAT1,ATP1A2,NCDN,HAP1,ATP13A2,CRB1,GUCY1A1,KCNK10,PTGDR2,PDE1C,SCRG1,MAPK10,STMN4,ARNT2,ATN1,EPB41" Drug 3718_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "NDRG2,C1orf61,TRIM46,SORBS1,DNAH17,ASPH,KAZN,GPR19,HAP1,GRIA1,PTGDR2,PDE4B,PKN2,PRDM2,STMN4,NKAIN1,SEC61A2" Drug 6093_UP Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "RYR1,ADORA1,CDC42BPA,GAS7,SLC2A5,BCO1,CCDC88A,BRINP2,ATP1A2,COLGALT2,GPM6A,NUMA1,CABP1,NOS1AP,PROX1,PLPPR4,ELAVL4" Drug 2985_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ABAT,AMPH,APC,MSR1,PDE8B,SLCO1A2,ADGRL3,GPM6B,NPPA,TCF7L2,CAMK2A,GRM3,OPCML,LILRA4,HPSE2,SSPN,EPB41L1" Drug 4666_UP Probucol [23288-49-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "DPF1,SELL,SLC1A7,ATP2B2,ADGRB2,PHLDB1,CACNA1A,TGFBR3,GUCY1A2,P2RX7,NEURL1,TNS1,ADGRG1,PLCH2,AK5,KCNMA1,VWA5A" Drug 2329_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "PAQR6,APC,BCAN,CADM3,GAD2,SPART,LMO3,GLS,POPDC3,BTRC,CACNA1A,WSCD1,SERPINE2,NOS1AP,KCND3,SRGAP3,KCNMA1" Drug 4637_DN Perphenazine [58-39-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "PDE8B,ASTN1,ATP2B2,ADGRB2,NDUFA5,KAZN,GNAS,ADGRL3,GPR17,CAMK2G,NUMA1,TNS1,NMT2,CABP1,PROX1,ATG16L1,FAM13C" Drug 3574_DN Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "EMID1,CCDC88A,ALDH4A1,EMC1,POPDC3,BTRC,CACNB2,ZEB1,TGFBR3,PCDH9,SULT4A1,PEX5,RAB3IL1,DNM2,RAD52,SUSD4,DSCAM" Drug 6963_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ABAT,SFPQ,CDC42BPA,PPFIA1,PKP4,DGKD,ZSWIM8,NASP,NUCB1,PSD3,RBFOX2,RBPJ,COPS7A,MED24,SMG7,RABGAP1L,KIF2A" Drug 3813_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FGF1,CDC42BPA,NTNG1,GAS7,RPH3A,TAGLN3,KAZN,GNAS,GNG3,MYRF,PSD3,CDC42,IFFO1,MAPK8,ITIH2,KCNMA1,DTNA" Drug 4396_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,ADORA3,AMPH,APBA2,SLC1A7,NPAS3,INKA2,AJAP1,MLC1,POPDC3,NPPA,ZEB1,GRIK4,NEURL1,TNS1,GPR37L1,PTAFR" Drug 4143_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FGF1,FGF14,AQP4,TAGLN3,COLGALT2,GPR162,SLCO1C1,POPDC3,ADGRL3,GUCY1A2,PAH,CDH10,SEZ6L,NECAB2,PTAFR,KCNMA1,RCAN2" Drug 4295_UP Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "EMID1,FOXG1,PKP4,BCAN,CADM3,GAD2,ALDH1L1,NCDN,RND1,ADGRL3,OMG,PCSK2,PIK3CD,FEZ1,MAPK8,JAKMIP2,STMN4" Drug 3784_UP Vincamine [1617-90-9]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TTYH1,EMID1,RASA3,ATP1A2,ACSBG1,GNG4,GPR17,NUMA1,PDE2A,JAM2,KIAA1549L,SULT4A1,SNCAIP,DNAH9,RASGRF1,EFNA3,LRRC23" Drug 2242_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MDM4,MOBP,SH3GL2,APBA2,SORBS1,NLGN1,AQP4,PDE8B,CADM3,SPART,RND1,AJAP1,POPDC3,PSD3,CDH8,PACSIN1,MAPK10" Drug 6489_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "KIAA1109,ASIC4,FHL1,APC,GAS7,SYBU,BRINP2,CCDC181,MYT1L,CADM3,RND1,CAMK2G,TNS1,SERPINE2,ATG16L1,EFNA3,VWA5A" Drug 2292_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MDM4,CDC42BPA,GAS7,SLC6A9,DNAH17,SORCS3,GAD2,SPART,FLRT1,SNCAIP,NCAN,RIMS3,PTCH1,ITIH2,KCNH1,RAB3IL1,EN2" Drug 4649_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ADORA1,ADORA3,HPCAL4,AQP4,SLC6A9,ASCL1,ASTN1,B3GAT1,SNAP25,KIF21B,CACNA1A,TGFBR3,TNS1,CDH10,ELMO1,AK5,KCNK2" Drug 2866_UP Budesonide [51333-22-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ADCY2,ADORA1,TUBB4A,CDC42BPA,SORBS1,MSR1,SLC14A1,ATM,NMNAT2,NPAS3,NEURL1,TPM3,SERPINE2,PIK3CD,PACSIN1,ARHGEF4,ATN1" Drug 3872_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ADORA1,TUBB4A,KIAA1109,APBA2,SLC2A5,SLCO1A2,BRINP2,NPAS3,AJAP1,ABCC8,CACNA1A,GRM3,TNS1,CHRNB2,RIMS3,ITIH2,TMCC2" Drug 2990_DN Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "NDRG2,CLIP1,FOXRED2,PLA2G6,ATP2B2,ZCCHC24,FAM168A,CAMSAP2,WWC1,TCF7L2,TNS1,PPP2R5C,VCAN,PLPPR1,RALGDS,RGS10,VWA5A" Drug 4645_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "SELL,APC,SLC2A5,ASCL1,ASTN1,CADM3,ADGRB2,BTRC,GRIK2,GRIK3,ADAMTS8,SPX,LILRA4,RGS6,KCND3,KCNJ4,ARNT2" Drug 5686_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,FHL1,SELL,APBA2,NTNG1,MYBPC1,NPAS3,AJAP1,VAMP1,HAP1,TF,PKN2,IGSF1,MAGI2,ATN1,DSCAM,ROM1" Drug 2989_DN Benzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MAPT,NDRG2,AGT,PLA2G6,ANK3,ADAM15,NCDN,CAMSAP2,PRUNE2,TCF7L2,RBFOX2,BEST1,CTNND1,RAB3IL1,DSCAM,SIDT2,RASGRP2" Drug 2095_UP Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TUBB4A,PLA2G6,TAGLN3,ASTN1,B4GALNT1,COLGALT2,SLCO1C1,ROBO3,GNG3,PRUNE2,NUMA1,OPCML,SEZ6L,CADM1,TOX,PLPPR4,RGS10" Drug 6069_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ANK1,RPH3A,SLC2A5,MSR1,TAGLN3,ATP1A3,KIF21B,COLGALT2,PHLDB1,NPPA,INA,CDH10,SEZ6L,SCRG1,SLC22A6,SERPINE2,KCND3" Drug 311_DN monastrol; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "NDRG2,SCNN1D,RPH3A,SHANK2,ASCL1,GAD2,KLHL4,CACNA1A,HAP1,TMEM151B,TNS1,CDH8,SEZ6L,TPD52,PTPRO,DTNA,NUP214" Drug 3633_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "DPF1,APC2,ADCY2,PLA2G6,ANK1,RASA3,SLC2A5,ATP2B2,GFAP,PHLDB1,INA,TNS1,NECAB2,POU3F2,ATRNL1,VCAN,TMCC2" Drug 3741_DN Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MAPT,FOXRED2,C1orf61,ADAM15,ADGRB2,BTRC,CACNB2,GRIK2,PC,PDE4B,PIK3CD,CTNND2,PTAFR,PARD6A,SRGAP3,AK5,DTNA" Drug 3047_UP Nizatidine [76963-41-2]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "LRRTM4,CSPG5,CCDC181,MYH7,ACSBG1,ASTN2,ROBO3,NPPA,OPCML,TPM3,PDE1C,PMP2,RGS6,JAKMIP2,KCNC1,PARD6A,RGS7" Drug 2635_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,ADORA1,C1orf61,AQP4,SLC2A5,ATP1A3,NPAS3,NDUFA5,NRXN1,CAMKV,FADS2,PACSIN1,MAPK8,RABGAP1L,SLC6A15,RGS10,SIDT2" Drug 5864_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "RYR1,MOBP,FOXG1,SELL,NTNG1,ALDH4A1,SNAP25,TNIK,NPAS3,ALDH1L1,MYRF,INA,CTNND2,SMG7,DLG3,PARP11,RASGRP2" Drug 6929_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,EMID1,F3,FYN,CLASP2,VAMP1,EML4,TNS1,FADS2,VAV2,RGS6,PARD6A,NAV2,RAD52,DSCAM,GNE,UEVLD" Drug 2754_DN Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FOXRED2,KIAA1109,ITSN1,APC,ASPH,ZSWIM8,ADAM15,CLASP2,ASTN2,PC,PCDH9,CCSER2,COL9A2,DZIP3,CTNND2,HP1BP3,DSCAM" Drug 4177_UP Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TUBB4A,APBA2,NTNG1,GAS7,ASTN1,ATP1A3,SOX10,MYH7,GLS,TMEM151B,GUCY1A1,KCNK10,MICAL2,VCAN,STMN4,KCNJ9,RASGRP2" Drug 2443_UP Cisapride [81098-60-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ABAT,SLCO1A2,SLN,GNG4,WWC1,GPM6B,HAP1,PSD3,ATP13A2,ZMYND8,CCSER2,NSD2,CTNND1,CTNND2,EDRF1,SMG7,ROM1" Drug 6456_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "RYR1,ADORA1,MOBP,SYBU,PDE8B,CADM3,NDUFA5,ACSBG1,ASTN2,POPDC3,WSCD1,OPCML,VAV2,PTAFR,KCND3,KCNMA1,ATN1" Drug 6516_UP Tiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "PLA2G6,ALDH4A1,CADM3,GNAS,NEURL1,PDE4B,PMP2,VCAN,PROX1,PTAFR,ITIH2,PRDM2,HP1BP3,KCND3,PEX5,DTNA,LRRC23" Drug 6876_UP BAS 012416453; Up 200; 38uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "F3,PLA2G6,SELL,APC,GAS7,MSR1,GART,PHLDB1,PDE2A,CHRM4,MICAL2,ARHGEF4,SYTL2,PTHLH,MAGI2,PLPPR4,RAD52" Drug 6668_UP Bemegride [64-65-3]; Up 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "RASA3,ADGRB2,PHLDB1,ACSBG1,MLC1,ASTN2,MYRF,HAP1,MED1,PSD,TOX,ITIH2,STMN4,RABGAP1L,ARNT2,DTNA,RGS7" Drug 2470_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "APC2,ADORA1,PLA2G6,HPCAL4,SH3GL2,GPR153,TAGLN3,SLN,TNIK,GPM6A,ACSL6,NPPA,HAP1,OMG,SULT4A1,MAPK8,RASGRP2" Drug 3541_UP Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,AGT,SELL,SYBU,BCO1,ZCCHC24,ACSBG1,GNAS,CACNB2,HAP1,PTGDR2,CHRNB2,PACSIN1,KCNA2,KCND3,SIDT2,RASGRP2" Drug 5384_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FHL1,HPCAL4,SORBS1,PKNOX2,PDE8B,BCL2L2,GLS,GNG3,WSCD1,ZEB1,CAMK2G,PAH,PDE3B,SDC3,NTM,KCNK2,EN2" Drug 5543_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ACTN2,LRRTM4,ASIC4,FHL1,SYBU,DNAH17,ASTN1,GAD2,EMC1,VAMP1,HAP1,GRIN1,PDE4B,EDRF1,KCNJ10,DTNA,ST8SIA3" Drug 1425_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "KIAA1109,FHL1,C1orf61,CDC42BPA,CADM3,GJB1,CAMSAP2,GRIA4,INA,RBFOX2,CHRNB2,CAMKV,CCSER2,GON4L,ATN1,RLBP1,EPB41L2" Drug 4476_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TTYH1,ADCY2,PLA2G6,MOBP,DOCK10,BCAS1,SCN3B,CADM3,ALDH1L1,GPR17,PDE3B,ADGRG1,CHRNB2,VAV2,MICAL2,SV2A,DTNA" Drug 2343_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,CCDC88A,KIF1B,GPM6B,PSD3,IFFO1,POU3F2,PPP2R5C,VCAN,PRKCZ,CTNND1,RIMS3,SMG7,C1orf109,RALGDS,SIDT2,ELAVL3" Drug 6700_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FOXG1,APC,SLC6A9,ASCL1,SLCO1A2,ZSWIM8,EMC1,P2RX7,TPM4,CHRNB2,COL9A2,NSD2,VCAN,MAPK8,ATN1,EFNA3,VWA5A" Drug 7541_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "EMID1,SEMA6A,GPR153,ATP1A3,PSD3,INA,NEURL1,RBFOX2,MAGI1,CAMKV,DZIP3,HP1BP3,RAB3IL1,DSCAM,DTNA,SSPN,ELAVL3" Drug 3338_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "KCNIP2,NDRG2,SLC30A10,C1orf61,SLC1A7,BCO1,CCDC181,ALDH1L1,INKA2,RND1,VAMP1,HAP1,GRM3,OMG,KCNMA1,RAD52,RASGRF1" Drug 3790_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TTYH1,MBP,ACTN2,MOBP,ITSN1,SLN,GRIA4,OMG,INA,P2RX7,CDH8,HRH3,CA14,CABP1,PRDM2,SMG7,EFNA3" Drug 5359_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FOXRED2,AGT,FHL1,SLC1A7,GAD2,CAMK2G,OMG,KCNK10,HRH3,CHRNB2,SDC3,GON4L,SMG7,KCND3,ATN1,RGS10,VWA5A" Drug 3013_UP Propantheline bromide [50-34-0]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ABAT,RYR1,PLA2G6,ANK2,PDE8B,ASPH,ZSWIM8,TNS1,SEZ6L,LILRA4,HPSE2,HPCA,SYTL2,PMEPA1,PTHLH,KCNH1,RASGRP2" Drug 2337_UP Kawain [500-64-1]; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "TUBB4A,ASIC4,HPCAL4,FOXG1,APC,PKNOX2,SLC6A9,KIF1B,PRUNE2,CAMK2G,NUCB1,NUMA1,GPR37L1,CCSER2,ST8SIA5,IFFO1,RASGRF1" Drug 5529_UP Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MOBP,C1orf61,PDE8B,ATP2B2,WDTC1,GUCY1A2,KCNK10,PDE4B,ZMYND8,ATRNL1,EDRF1,MASP1,MAGI2,KCND3,TMCC2,ATG16L1,DSCAM" Drug 6686_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "EMID1,MDM4,MOBP,ANK2,BCAS1,SLC6A9,B3GALT2,SOX10,NCAM1,ALDH1L1,INKA2,ACSBG1,GRIN1,NECAB2,MICAL2,ITIH2,VWA5A" Drug 6309_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ARID1A,CCDC88A,PDE8B,INKA2,PHLDB1,GPR17,GRIN1,CDH10,PIK3CD,CRMP1,PTCH1,DNAJC6,RAB3IL1,RAD52,RALGDS,ATN1,EFNA3" Drug 4728_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,EMID1,FOXG1,APBA2,NTNG1,SLC14A1,ALDH1L1,INKA2,RND1,GNAS,HAP1,GRIK2,OMG,PTHLH,RAD52,ELAVL3,RASGRP2" Drug 2303_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MAPT,CDHR1,FHL1,CDC42BPA,APC,NTNG1,SLC6A9,ZCCHC24,DAAM2,PTGDR2,GPR37L1,NCAN,MAPK10,PTHLH,RAB3IL1,CAMK1G,RASGRP2" Drug 5644_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "FHL1,MOBP,C1orf61,CDC42BPA,RASA3,APC,NLGN1,SLC2A5,KCNK10,TNS1,SEZ6L,PDE1C,CNTN1,SYNC,KCNMA1,DTNA,ELAVL3" Drug 2406_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "MAG,PDE8B,ALDH4A1,GNG4,NPPA,NUMA1,CHGA,CHI3L2,CHRNB2,ZFYVE9,SULT4A1,PRKCZ,CTNND1,PHYHIP,PEX5,ST8SIA3,OLIG2" Drug 6461_DN Clioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.58E-03 1.00E+00 3.87E-02 4.25E-01 17 199 "ASIC1,MAPT,PLA2G6,SEMA6A,ITSN1,BCAN,ZCCHC24,ADAM15,ASTN2,NUCB1,CHD1L,DTNA,RET,SEC61A2,SSPN,EFNA3,VWA5A" Drug CID000656673 chromomycin A3 Stitch 2.63E-03 1.00E+00 3.94E-02 4.32E-01 11 103 "FOXG1,GFAP,CNTN2,CACNA1A,ZEB1,PAH,UBTF,PACSIN1,PRTFDC1,ATN1,EN2" Drug CID000019654 chlorate Stitch 2.63E-03 1.00E+00 3.94E-02 4.32E-01 11 103 "WAC,FGF1,SELL,SCG3,CNTN2,CYB561A3,PCSK2,SERPINE2,NEGR1,SDC3,ATN1" Drug CID000000723 2-butenedioate Stitch 2.66E-03 1.00E+00 3.99E-02 4.37E-01 19 234 "ACHE,FOXG1,ASRGL1,FOLH1,ATP2B2,ADHFE1,GLS,GRIA1,GRIA2,GRIA4,GRIK3,GRIK4,CYB561A3,GRM3,PC,HRH3,PDE2A,HNRNPK,PNKD" Drug CID000002303 Bay K 8644 Stitch 2.68E-03 1.00E+00 3.99E-02 4.37E-01 14 150 "KCNIP2,RYR1,AGT,ATP2B2,CACNA1A,CACNA1E,NPPA,CACNB2,CHRM1,PIK3CD,PRKACB,PRKCG,KCNA4,CACNG7" Drug CID000073212 lead compounds Stitch 2.68E-03 1.00E+00 3.99E-02 4.37E-01 14 150 "ADCY2,RYR1,ATP1A2,CACNA1A,GRIA1,KCNK10,HNRNPK,PRKCG,PKN2,PRKCZ,ITGAV,CA10,KCNK2,DTNA" Drug CID000446236 B-Ni Stitch 2.69E-03 1.00E+00 3.99E-02 4.37E-01 5 25 "MAG,BCAN,TNR,PDYN,VCAN" Drug CID000122028 "PD 81,723" Stitch 2.69E-03 1.00E+00 3.99E-02 4.37E-01 5 25 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3" Drug 6874_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.70E-03 1.00E+00 3.99E-02 4.37E-01 16 183 "ABAT,MAPT,F3,RGL1,RND1,ACSBG1,GLS,VAMP1,TNS1,PCDH9,CHRNB2,KIAA0513,SYTL2,PRDM2,VWA5A,ROM1" Drug 3795_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ACTN2,RYR1,APBB1,APC,ASPH,B3GAT1,ATP2B2,NFASC,GFRA1,AJAP1,SEMA4A,NEURL1,GPR37L1,TENM4,PROX1,TOX,PTAFR" Drug 4088_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ASIC1,MOBP,GAS7,PDE8B,WDTC1,EMC1,ASTN2,GPM6B,OPCML,NSD2,CRMP1,TENM4,EDRF1,PLPPR4,ATG16L1,SIDT2,LRRC23" Drug CID000005775 phentolamine Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ADCY2,ADORA1,ADORA3,AGT,BCO1,ARFGAP2,B3GAT1,ATP1A2,ATP1A3,HRH3,PDYN,CHRM1,CHRNB2,UBTF,PYGM,DLG3,RET" Drug 4787_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ACTN2,FABP7,FHL1,APBA2,BRINP2,RGL1,BTRC,TGFBR3,PLEKHB1,PIK3CD,FADS2,MICAL1,ARHGEF4,JAKMIP2,KCND3,EFNA3,EN2" Drug 6415_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ADORA1,SEMA6A,BCAN,FYN,ZCCHC24,ASTN2,POPDC3,ATF7,PC,PIK3CD,RGS6,RIMS3,SYNC,PTAFR,PARD6A,RAB3IL1,SIDT2" Drug 6521_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "F3,C1orf61,NLGN1,BCAS1,SHANK2,GLS,PSD3,CDH8,CDH10,CHRNB2,EDRF1,SYNC,RABGAP1L,DLG3,RAB3IL1,SIDT2,VWA5A" Drug 5755_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "HPCAL4,FOXG1,C1orf61,APC,SLC1A7,PKNOX2,WDTC1,KIF21B,NDUFA5,ASTN2,PADI2,PLEKHB1,SNCAIP,RIMS3,ITIH2,DTNA,VWA5A" Drug 2449_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "CDHR1,MBP,HPCAL4,NTNG1,ASPH,RND1,CAMSAP2,NPPA,ATP13A2,CRB1,CNTN1,ITIH2,PID1,BEND5,PAK5,NUP214,EFNA3" Drug 6509_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "APBA2,SLC2A5,ADAM15,MLC1,GNAS,GPR37L1,CAMKV,PMP2,NSD2,ARHGEF4,PROX1,PTCH1,HP1BP3,SV2A,ATG16L1,RASGRF1,EFNA3" Drug 2141_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "KIAA1109,HPCAL4,CDC42BPA,AQP4,RPH3A,MSR1,GPR153,CAMSAP2,MYRF,BTRC,NUMA1,SULT4A1,SYTL2,NAV2,ST8SIA3,EEF1A2,SEC61A2" Drug 3538_UP Condelphine [7633-69-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "RYR1,KIAA1109,SELL,MSR1,INKA2,RND1,GLS,GPM6B,GRIN1,PDE3B,CHRNB2,POU3F4,VCAN,SDC3,MAGI2,TTLL7,VWA5A" Drug 2190_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ABAT,KIAA1109,FOXG1,C1orf61,PPM1E,APC,PDE8B,ALDH4A1,WDTC1,ZCCHC24,SPART,BCL2L2,ATP13A2,DUSP26,CCSER2,SMG7,DSCAM" Drug 885_UP 5186223; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ARID1A,WLS,F3,KIAA1109,FGF1,RASA3,SPART,ASTN2,BTRC,GPM6B,TCF7L2,USP2,VAV2,CTNND2,KIF2A,DTNA,RGR" Drug 4639_DN Felbinac [5728-52-9]; Down 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MAPT,FOXRED2,CCDC88A,ASPH,ALDH4A1,NDUFA5,ADGRL3,GPR17,NUMA1,OPCML,PLEKHB1,CADM1,NSD2,PRKAB2,SDC3,GON4L,BEND5" Drug 2199_UP Myosmine [532-12-7]; Up 200; 27.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MSR1,PDE8B,B3GAT1,ATP2B2,WDTC1,PCDH9,PTGDR2,SEZ6L,ADGRG1,CHRNB2,NMT2,BEST1,MAPK8,SMG7,KCNMA1,RAD52,DSCAM" Drug 2788_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "SYNDIG1,ANK1,BCAS1,SLC1A7,DNAH17,DLL3,SLN,GAD2,EMC1,AJAP1,PDE1C,ASIC3,CA10,ITIH2,RAD52,PARP11,VWA5A" Drug 3167_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "DPF1,RPH3A,MSR1,TAGLN3,NFASC,GPM6B,NEURL1,SEZ6L,PRMT8,ADGRG1,BEST1,VCAN,PTPRD,KCNC1,FAM13C,DTNA,SSPN" Drug 5621_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ACTN2,FHL1,SLC2A5,CCDC88A,RND1,VAMP1,WSCD1,ZEB1,OPCML,PTGDR2,IFFO1,SF1,SMG7,SIDT2,VWA5A,LPAR6,EPB41" Drug 5400_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ARID1A,PLA2G6,GAS7,MSR1,MYH7,EMC1,NEUROD1,POPDC3,ZEB1,OPCML,INA,PRMT8,CHRNB2,NECAB2,PKN2,ARHGEF4,MAPK10" Drug 4598_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MDM4,C1orf61,DOCK10,BCAN,CCDC88A,CSPG5,CACNA1A,OPCML,NEURL1,MAGI1,PDE4B,ADGRG1,HMGB1,CADM1,KCNJ4,RAB3IL1,ELAVL3" Drug CID003034747 C070379 Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "RYR1,ADORA3,AGT,FGF1,ATP2B2,CACNA1E,GRM3,P2RX7,CDC42,TPD52,CHRM1,HPCA,PRKACB,PRKCG,MAPK8,MAPK10,RAP1GAP" Drug 3182_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "PRR5L,ADORA3,AGT,PKNOX2,SHANK2,SOX10,RND1,ROBO3,CDK5R2,GRM3,TLL2,NRXN2,SULT4A1,POU3F2,SYNC,KCND3,ATN1" Drug 6701_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "FGF1,SELL,PKP4,APC,AQP4,NASP,ASTN2,BTRC,TPM3,SCRG1,JAM2,CRMP1,MICAL2,KCNMA1,DTNA,EFNA3,ARHGAP12" Drug 3398_UP Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "NDRG2,ADCY2,ADORA3,FHL1,DLL3,ATP1A2,VAMP1,ATF7,OMG,PCDH8,CDH8,HPSE2,PLEKHB1,MAPK8,PTHLH,KCNMA1,ELAVL3" Drug 5412_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "EMID1,NDRG2,RYR1,PLA2G6,FHL1,SHANK2,SLCO1A2,POPDC3,ZEB1,GUCY1A1,NEURL1,PDE3B,SDC3,CNIH3,KCNJ4,DTNA,ELAVL4" Drug 3619_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MAPT,EMID1,ADORA1,SEMA6A,SORBS1,NEUROD1,RND1,CAMK2G,USP2,INA,PIK3CD,MICAL2,CA10,KCNC1,ATN1,RAVER2,RASGRP2" Drug 3765_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ASIC1,RYR1,AQP4,ASTN1,NFASC,NEUROD1,SLCO1C1,GNG4,ADGRL3,TMEM151B,NUMA1,ADAMTS8,CHRNB2,SPATA6,ELAVL3,ROM1,RCAN2" Drug 3735_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "TTYH1,KIAA1109,ANK3,DNAH17,SCN3B,ALDH1L1,ASTN2,GNG3,ADGRL3,GPR19,OPCML,TNS1,PDE4B,MAPK8,DSCAM,ABCC9,LPAR6" Drug 4002_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ABAT,FABP7,PLA2G6,SOX10,NFASC,NCAM1,PHLDB1,ACSBG1,BTRC,KLHL4,GPM6A,GRIN1,TPM3,NCAN,SMG7,BEND5,ABCC9" Drug 3689_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "KIAA1109,HPCAL4,MOBP,C1orf61,NLGN1,ADGRB2,NFASC,GRIN1,CRB1,TNFRSF1B,TMPRSS5,NRXN1,RIMS3,PRDM2,SUSD4,ATN1,RASGRF1" Drug 4094_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MDM4,SCNN1D,KIAA1109,MOBP,GAS7,DDX25,BRINP2,NUCB1,GRIA4,SPX,PHKG1,PMP2,NSD2,MICAL2,KCND3,RAB3IL1,DSCAM" Drug 4505_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "MDM4,PLA2G6,CDC42BPA,APC,CGREF1,ASPH,WDTC1,B4GALNT1,COLGALT2,KAZN,GNG4,BTRC,NUMA1,POU3F2,PLPPR1,PLPPR4,KIF2A" Drug 5626_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "DPF1,APBA2,GAS7,SORBS1,KIF21B,RGL1,POPDC3,ROBO3,USP2,PCSK2,NECAB2,MAPK10,GON4L,PTAFR,TTLL7,VWA5A,EN2" Drug 4173_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "RASA3,APBA2,GAS7,SLC14A1,ALDH1L1,ABCC8,CDK5R2,GRIA1,KCNK10,PAX6,MICAL2,PTPRD,NTM,KCNMA1,PARP11,ATN1,ELAVL3" Drug 6502_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "ARID1A,NDRG2,TUBB4A,GAS7,ATM,NEUROD1,KAZN,WSCD1,PSD3,OPCML,PCDH9,PTGDR2,CHGA,ARHGEF4,HP1BP3,KCND3,ATN1" Drug 666_UP butirosin A from Bacillus vitellinus; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "CDC42BPA,PPFIA1,SLC2A5,EIF4G3,OPCML,CDH8,ADGRG1,TMPRSS5,CHRNB2,FADS2,CNTN1,MED1,KCNJ9,KCNMA1,RAP1GAP,ELAVL4,BSCL2" Drug 252_UP celecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.72E-03 1.00E+00 3.99E-02 4.37E-01 17 200 "NDRG2,ADORA1,ASIC4,FGR,DGKD,FXYD6,GLS,CAMK2A,TNS1,PTGDR2,ASIC3,PACSIN1,DZIP3,MAPK8,KCNA4,NUP214,ST8SIA3" Drug CID006450460 avermectin Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 7 48 "GRIA1,GRIA2,GRIA4,GRID1,GRIK4,GRM3,UEVLD" Drug CID000003202 edrophonium Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 7 48 "ACHE,OMG,PDE4B,CHRM1,CHRNB2,SHD,PHC2" Drug CID000072293 "phorbol 12,13-diacetate" Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 7 48 "FGF1,SNAP25,GABBR1,GRIA1,GRIA4,GRM3,PRKCG" Drug CID000428025 ts M Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 7 48 "ACHE,RYR1,FOLH1,API5,B3GAT1,ACSBG1,PTPN5" Drug CID000001253 (+/-)-Huperzine A Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 6 36 "ACHE,MBP,GFAP,CHRM1,NAV2,ELAVL4" Drug ctd:D005033 Ethylmaleimide CTD 2.72E-03 1.00E+00 3.99E-02 4.37E-01 6 36 "F3,MT3,GAD2,TF,PAH,PYGM" Drug CID000001676 enprofylline Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 6 36 "ADAR,ADARB2,ADORA1,ADORA3,P2RX7,PDE4B" Drug CID000006853 fluorene Stitch 2.72E-03 1.00E+00 3.99E-02 4.37E-01 6 36 "SLC1A2,RND1,GRIK4,TMEFF2,MASP1,CA10" Drug ctd:C088658 zoledronic acid CTD 2.74E-03 1.00E+00 4.02E-02 4.41E-01 80 1472 "SERPINA3,ASIC1,ADGRV1,WLS,MDM4,F3,TUBB4A,NLGN4X,BCAR3,FHL1,BBOX1,HPCAL4,SELL,ANK2,PKP4,DOCK10,NTNG1,API5,ZNF365,SLC14A1,SORCS3,SNAP25,MEGF11,WDTC1,DNER,BCL2L2,RGL1,GJB1,PHLDB1,RND1,PSRC1,PRUNE2,WSCD1,DDR1,EML4,SPX,TNFRSF1B,REPS2,CDC42,ARHGAP19,PDE1A,PDE4B,GPR37L1,ADGRG1,CHI3L2,ARHGAP22,SEMA5B,ANLN,FADS2,COL9A2,MFSD4A,CP,PNKD,CRLS1,TENM4,FEZ1,PRKAB2,PRKACB,PLD5,ARHGEF4,MAPK8,MAPK10,KLK6,RIMS3,SYTL2,TUBB2B,ZNF385B,PTHLH,PRTFDC1,HP1BP3,PARD6A,KCNH1,SRGAP3,AK5,RABGAP1L,ARNT2,NAV2,RAB5B,RAP1GAP,BEND5" Drug CID000003667 IAA-94 Stitch 2.76E-03 1.00E+00 4.03E-02 4.42E-01 8 61 "ACLY,RYR1,AGT,CACNA1A,CACNA1E,CACNB2,BEST3,CACNG7" Drug CID000003868 "pyrrolidine-2,4-dicarboxylate" Stitch 2.76E-03 1.00E+00 4.03E-02 4.42E-01 8 61 "SLC1A2,ABCC8,GRIA1,GRIA2,GRIA4,GRM3,OMG,SLC17A6" Drug CID006324619 Compound-1 Stitch 2.79E-03 1.00E+00 4.08E-02 4.47E-01 12 119 "ACHE,PDZD4,CCDC80,WDTC1,AHCYL1,GART,NASP,HPS5,HRH3,PRKACB,ROM1,RCAN2" Drug 966_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.79E-03 1.00E+00 4.08E-02 4.48E-01 15 167 "SELL,ALDH4A1,AJAP1,KAZN,GNG4,PFKFB3,ZFYVE9,TENM4,MICAL2,MAPK8,KLK6,NAV2,RAP1GAP,RET,EPB41L1" Drug CID000030956 AC1L1KMJ Stitch 2.82E-03 1.00E+00 4.12E-02 4.52E-01 32 476 "APC2,CLIP1,TUBB4A,ACTL6B,ANK1,ANK2,ANK3,GAS7,TAGLN3,NRG3,FYN,TF,OLR1,TJP1,CDC42,TPD52,TPM3,TPM4,CHRM1,PIK3CD,TJP2,CNTN1,CABP1,COL9A2,ATCAY,PRKACB,CALY,PRKCG,MAPK8,TUBB2B,DNM2,ABI2" Drug ctd:D000535 Aluminum CTD 2.83E-03 1.00E+00 4.14E-02 4.54E-01 98 1869 "MAPT,ACHE,ACLY,RTN3,RCSD1,DSCAML1,ERMN,ASIC4,BBOX1,UNC79,ELMOD1,PI16,USP28,SESN3,BCAS1,SLC1A2,MIER1,SLC1A6,SFMBT2,MSR1,LRRC55,SLC8A3,SHANK2,SCMH1,SLCO1A2,CAPRIN2,MTR,RCOR3,NEK6,IDI2-AS1,DNER,C11orf87,COLGALT2,GFAP,RGL1,RHBDL3,NODAL,CDK5R2,ADGRL3,TMEM136,TBX15,PRUNE2,ATF7,LRIT2,CLEC9A,GPR17,GPR26,CAMK2A,TMEM151B,NUMA1,PSD3,GRID1,TF,OPCML,TGFBR3,ZDHHC22,TNFRSF1B,PADI2,LILRA4,ZNF384,PDE1A,PDE4B,ZMYND8,PHKG1,NRXN1,CNTN1,CELF5,PRRX1,NSD2,FAT3,NXPH1,ETNPPL,MICAL2,PROX1,ZBTB16,PSD,KIAA0513,PTHLH,ITIH2,CNIH3,KCNA6,KCNC1,SRGAP3,ARNT2,PCDH15,KLRC3,DBX2,USH1C,ST8SIA3,RLBP1,SFXN5,RERGL,RAVER2,SLC4A10,OLIG2,EPB41,EPB41L1,RASGRP2" Drug CID000004101 methenamine silver Stitch 2.86E-03 1.00E+00 4.18E-02 4.58E-01 17 201 "SERPINA3,RTKN,CLIP1,ACTL6B,BCAR3,WDTC1,RND1,DAAM2,CDC42,SERPINE2,ANLN,PRKCZ,MAPK8,SPIRE1,SRGAP3,ABI1,VANGL2" Drug ctd:D012402 Rotenone CTD 2.88E-03 1.00E+00 4.19E-02 4.60E-01 57 983 "MAPT,ACHE,MBP,ADAR,TUBB4A,AGT,FGF1,ASRGL1,SH3GL2,GAS7,GPAM,RUFY2,MSR1,MT3,ATM,ATP1A2,ATP2B2,KIF1B,NASP,BCL2L2,NDUFA5,GFAP,GFRA1,RND1,BTRC,CNTN2,EML4,CAMK2A,CAMK2G,ATP13A2,TJP1,AIFM1,ZFP91,CD81,CDC42,PDE3B,SERPINE2,NMT2,CNTN1,CP,CRMP1,SNCAIP,MAPK8,MAPK10,FAM131B,TUBB2B,DNAJC6,PTPRD,KCNJ4,ATG16L1,CAMK1G,RET,SSPN,RBM12,CBLN2,EN2,RASGRP2" Drug ctd:D004051 Diethylhexyl Phthalate CTD 2.96E-03 1.00E+00 4.31E-02 4.73E-01 89 1673 "SERPINA3,RIMKLA,MAPT,ACLY,SYNDIG1,ACTN2,MEG3,NDRG2,RYR1,FABP7,ADORA3,CHST15,TOMM40L,AGT,PLA2G6,LRRC7,PI16,ANXA7,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A6,SLC6A9,YPEL4,SHANK2,SLIT1,ALDH4A1,ATM,FYN,SCN3B,SOX5,ILDR2,GAD2,NMNAT2,GFAP,NFIA,GLS,GNAS,MYRF,CACNA1A,GPM6A,GPR19,CAMK2G,NUCB1,GRIA2,GRIA4,RFFL,GRIK2,GRIN1,VWCE,TF,MFSD2A,FBXL16,CD81,MAEL,PAX6,TNS1,CDH8,CHGA,PLEKHB1,ZBED5,HNRNPK,DLGAP3,CADM1,NRXN1,NRXN2,UBTF,FADS2,DNAJC12,PNKD,RNF14,PPP2R5C,ZBTB16,TUBB2B,PSMD13,PTCH1,DNAJC6,MAGI2,KCNK1,PCDH15,KCNMA1,KCNN3,PYGM,DPP6,RASGRF1,CACNG7,FGFBP3,RCAN2" Drug CID000003488 glibenclamide Stitch 2.96E-03 1.00E+00 4.31E-02 4.73E-01 27 382 "ADORA1,ADORA3,FGF1,FOXM1,ABCC8,NPPA,CACNB2,GUCY1A2,KCNK10,CHRM1,SLC22A6,CPT1C,FTO,PRKACB,PRKCG,KCNA1,KCNA2,KCNA6,KCNJ4,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNMA1,KCNN3,KCNQ2,ABCC9" Drug 2532_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.01E-03 1.00E+00 4.37E-02 4.79E-01 16 185 "ADORA3,KIAA1109,FHL1,PPM1E,SHANK2,ATP1A3,GAD2,GNG4,PTGDR2,CCSER2,BEST1,PRKCZ,ZBTB16,PTAFR,PTCH1,DSCAM" Drug 4365_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.01E-03 1.00E+00 4.37E-02 4.79E-01 16 185 "TESK2,FAM168A,VAMP1,ASTN2,SEMA4A,CAMK2G,ZMYND8,FADS2,SDC3,IGSF1,RIMS3,LRP8,RAB3IL1,RALGDS,RET,PLEKHO1" Drug 2949_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.01E-03 1.00E+00 4.37E-02 4.79E-01 16 185 "FHL1,PPM1E,APC,PALLD,TNIK,NCAM1,NDUFA5,RGL1,CAMSAP2,ATP13A2,PADI2,PCDH9,RBFOX2,FEZ1,DNAJC6,EFNA3" Drug CID000017533 DDOH Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ADHFE1,PTPN5,HPR" Drug CID000010930 isovaleramide Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ADHFE1,SV2A,KCNQ2" Drug CID000125422 nI-pI Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "TF,HPR,CP" Drug CID006918293 valrocemide Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ADGRV1,SV2A,KCNQ2" Drug CID005326876 3-CB Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "F3,ATM,NDUFA5" Drug DB01016 Glyburide Drug Bank 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ABCC8,KCNJ11,ABCC9" Drug CID000009330 benactyzine Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ACHE,GART,CHRM1" Drug ctd:C117446 cangrelor CTD 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "F3,GPR17,P2RY12" Drug CID000407009 5H-purine Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "ADORA1,ADORA3,ADHFE1" Drug CID000125327 Gly-gly-cys Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "MBP,ASCL1,GFAP" Drug DB00228 Enflurane Drug Bank 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "GRIA1,KCNA1,KCNMA1" Drug CID000027423 TMPTA Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "MAG,DNER,PMS2" Drug CID000018177 dichloroacetonitrile Stitch 3.02E-03 1.00E+00 4.37E-02 4.79E-01 3 8 "BCAN,SOX10,TOX" Drug CID003064778 HA1 100 Stitch 3.03E-03 1.00E+00 4.38E-02 4.81E-01 10 90 "KLRC4,CDC42BPA,WWC1,NRGN,GRIA1,GRIA2,GRIA4,GRM3,PARD6A,EEF1A2" Drug CID000023926 lanthanum Stitch 3.05E-03 1.00E+00 4.40E-02 4.83E-01 13 136 "ADCY2,RYR1,ATP2B2,CACNA1A,CACNA1E,CACNB2,TJP1,AIFM1,CABP1,KCNA1,ABI1,NUP214,CACNG7" Drug CID000005604 NSC56408 Stitch 3.06E-03 1.00E+00 4.41E-02 4.84E-01 8 62 "ADAR,ADARB2,ADORA1,ADORA3,AHCYL1,TUB,UBTF,PRKACB" Drug CID000196705 alpha-CaM Stitch 3.06E-03 1.00E+00 4.41E-02 4.84E-01 8 62 "MAPT,LRRC7,SHANK2,B3GAT1,GJB1,NRGN,PRKCG,CTNND2" Drug CID000010535 neuroNal Stitch 3.07E-03 1.00E+00 4.43E-02 4.85E-01 7 49 "ASIC1,ACHE,ASIC4,TAGLN3,OMG,LGI1,CHRNB2" Drug CID000107720 indoxacarb Stitch 3.07E-03 1.00E+00 4.43E-02 4.85E-01 7 49 "ASIC1,SCN3A,SCN4B,SCNN1D,ASIC4,SCN3B,ASIC3" Drug CID000198756 repinotan Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000069961 methionine sulfone Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "MSRA,MTR,GLS,CCKBR" Drug CID006438356 Men 10627 Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "TUBB4A,B3GAT1,GNAS,PTCH1" Drug CID000006145 phenylurea Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "WLS,SOX10,CCKBR,PMP2" Drug CID000008614 hippuran Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "AGT,NPPA,NUCB1,ELAVL3" Drug CID000003290 ethopropazine Stitch 3.08E-03 1.00E+00 4.43E-02 4.86E-01 4 16 "ACHE,ATM,GART,CHRM1" Drug CID000004624 6-OHDA Stitch 3.11E-03 1.00E+00 4.48E-02 4.91E-01 20 255 "MAPT,ACHE,SLC1A2,SNCB,GAD2,ARPP21,GFAP,GFRA1,GRIA1,GRIA2,GRIA4,HRH3,PDE4B,PDYN,CHRM1,MAPK10,KLK6,SLC17A6,RET,EEF1A2" Drug CID000000791 hilE Stitch 3.13E-03 1.00E+00 4.49E-02 4.93E-01 9 76 "ABAT,APC,SLC1A2,SLC1A6,SLC1A7,PAH,PTCH1,PYGM,SLC6A15" Drug CID000004794 glufosinate Stitch 3.13E-03 1.00E+00 4.49E-02 4.93E-01 9 76 "RYR1,ADD3,APBB1,CACNA1A,CACNA1E,HPSE2,SF1,CEP170,DPP6" Drug CID000003333 felodipine Stitch 3.13E-03 1.00E+00 4.50E-02 4.93E-01 15 169 "RYR1,AGT,PDE8B,ADHFE1,CACNA1A,CACNA1E,NPPA,CACNB2,PDE1A,PDE1C,PDE2A,PDE3B,PDE4B,CALN1,CACNG7" Drug CID000001830 I TU Stitch 3.14E-03 1.00E+00 4.51E-02 4.94E-01 6 37 "ADAR,ADARB2,ADORA1,ADORA3,PTPA,PYGM" Drug CID000009643 "1,2-dichlorohexafluorocyclobutane" Stitch 3.14E-03 1.00E+00 4.51E-02 4.94E-01 6 37 "RYR1,GRIA1,GRIK2,TPM3,CHRM1,PRKCG" Drug CID004133412 benzyloxyaspartate Stitch 3.14E-03 1.00E+00 4.51E-02 4.94E-01 6 37 "SLC1A2,SLC1A7,GFAP,GRM3,HMGB1,PTCH1" Drug 6891_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.17E-03 1.00E+00 4.55E-02 4.99E-01 16 186 "F3,TUBB4A,ZNF365,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,SERPINE2,PIK3CD,DNAJC12,KIAA0513,DNAJC6,EFNA3" Drug CID000004159 medrol Stitch 3.17E-03 1.00E+00 4.55E-02 4.99E-01 16 186 "SERPINA3,MBP,IL17D,ASRGL1,GFAP,NODAL,TF,PTPN5,LEFTY2,TNFRSF1B,PDYN,CHRM1,CHRNB2,HPR,A2ML1,CP" Drug 6987_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.17E-03 1.00E+00 4.55E-02 4.99E-01 16 186 "MAPT,PAQR6,TESK2,GAS7,GLS,VAMP1,SEMA4A,TCF7L2,NUMA1,CCKBR,REPS2,HPCA,NECAB2,FEZ1,RAB3IL1,SIDT2" Drug 7499_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.17E-03 1.00E+00 4.55E-02 4.99E-01 16 186 "TUBB4A,SYBU,FYN,ZCCHC24,KIF21B,RGL1,RND1,ACSBG1,GLS,PCDH9,PIK3CD,KIAA0513,PTCH1,DNAJC6,JAKMIP2,NAV2" Drug CID000173454 gangliotetraose Stitch 3.22E-03 1.00E+00 4.60E-02 5.05E-01 5 26 "MAG,B3GAT1,B4GALNT1,NKX6-2,NEU4" Drug CID000132846 "L-733,060" Stitch 3.22E-03 1.00E+00 4.60E-02 5.05E-01 5 26 "FOXM1,B3GAT1,GRIN1,CCKBR,HRH3" Drug CID000132123 AIT-082 Stitch 3.22E-03 1.00E+00 4.60E-02 5.05E-01 5 26 "ACHE,FGF1,GAD2,ZFP91,TNFRSF1B" Drug ctd:D008767 Methylmercury Compounds CTD 3.22E-03 1.00E+00 4.60E-02 5.05E-01 51 863 "SERPINA3,RPL38,MAPT,ACHE,MBP,NDRG2,RTN1,FABP7,TUBB4A,AGT,FOXG1,APC,SLC1A2,SLIT1,SMARCE1,SNAP25,FYN,ATP2B2,SOX5,MYH7,SALL3,NFASC,NCAM1,GFAP,NEUROD1,ACSBG1,VAMP1,ZNF638,CAMSAP2,GOLGB1,TCF7L2,PTBP2,GRIK2,INA,PAH,CDC42,TPM3,CHRM1,ZBED5,HNRNPK,SLC22A6,CCSER2,FADS2,CP,CSF3R,CTNND1,MAPK8,RAP1GAP,RGR,EEF1A2,ELAVL4" Drug CID000285703 AC1L63MU Stitch 3.23E-03 1.00E+00 4.62E-02 5.07E-01 25 347 "APC2,ADCY2,AGT,PLA2G6,FOXG1,NODAL,NPPA,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRIK4,GRM3,LEFTY2,PTGDR2,HRH3,PRKACB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PTAFR,PYGM" Drug CID000081248 12:00 PM Stitch 3.27E-03 1.00E+00 4.67E-02 5.12E-01 21 274 "SCNN1D,MSR1,SOX5,NCAM1,VAMP1,NODAL,CACNA1A,OLR1,LEFTY2,TNFRSF1B,ZNF384,PTHLH,KCNA1,KCNA2,KCNA4,KCNA6,PYGM,RAD52,PARP11,ATN1,ABCC9" Drug CID000003104 AC1L1F6H Stitch 3.30E-03 1.00E+00 4.70E-02 5.16E-01 11 106 "ADAR,ADARB2,ADCY2,ADORA1,ADORA3,APC,CACNA1A,CACNA1E,P2RX7,CHRM1,P2RY12" Drug ctd:D008345 Manganese CTD 3.31E-03 1.00E+00 4.72E-02 5.17E-01 32 481 "ACHE,MBP,DSCAML1,FCGR1A,AGT,FHL1,SLC30A10,AQP4,SLC1A2,DACH2,ATM,ATP1A3,SCN3B,MYT1L,STOX1,GFAP,NPPA,CAMK2A,GRIN1,ATP13A2,TF,LEFTY2,GUCY1A1,RGS6,ARHGEF4,MAPK8,ITIH2,KCNJ11,SFXN5,ABI2,SLC4A10,RPE65" Drug ctd:C012606 4-vinyl-1-cyclohexene dioxide CTD 3.31E-03 1.00E+00 4.72E-02 5.18E-01 15 170 "ACHE,PLA2G6,SFPQ,ARHGAP5,KIF1B,NFIA,PTPN5,TGFBR3,MED1,PPP2R5C,PRKAB2,PRKACB,MAPK8,SIRPA,ITGAV" Drug 5698_UP Perphenazine [58-39-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.35E-03 1.00E+00 4.77E-02 5.23E-01 16 187 "NDRG2,HPCAL4,BCO1,PKNOX2,ZCCHC24,RND1,AJAP1,POPDC3,HAP1,CHRNB2,DNAJC12,PTCH1,PARP11,RASGRF1,SSPN,RASGRP2" Drug 4364_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.35E-03 1.00E+00 4.77E-02 5.23E-01 16 187 "NDRG2,TUBB4A,MOBP,APBA2,FYN,WSCD1,ZEB1,GRIK2,CCKBR,PIK3CD,CRMP1,VCAN,NOS1AP,STMN4,SV2A,KCNMA1" Drug 3893_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.35E-03 1.00E+00 4.77E-02 5.23E-01 16 187 "CLIP1,FGF1,FOXG1,ANK2,ATP1A3,FYN,ATP2B2,RND1,ABCC8,NKX2-2,OMG,TNS1,PTGDR2,CNTN1,CRTAC1,ELAVL3" Drug CID004632022 GB-C Stitch 3.38E-03 1.00E+00 4.82E-02 5.28E-01 8 63 "NEUROD1,ABCC8,TMEFF2,SERPINE2,HES5,SIRPA,PRDM2,ABCC9" Drug CID000025437 cerbroside Stitch 3.42E-03 1.00E+00 4.87E-02 5.34E-01 9 77 "MAG,MBP,NKX6-2,NEU4,PMP2,PRKCG,PKN2,PRKCZ,SHD" Drug CID000104978 fluo-3 Stitch 3.43E-03 1.00E+00 4.87E-02 5.35E-01 12 122 "RYR1,ADORA1,AGT,ATP2B2,GJB1,CACNB2,GRIK3,P2RX7,PRKCG,PTPRD,KCNMA1,LPAR6" Drug CID000026010 GaCl3 Stitch 3.45E-03 1.00E+00 4.90E-02 5.37E-01 7 50 "TUBB4A,GPR162,NEUROD1,TF,PMP2,TUBB2B,ITIH2" Drug CID000001324 "(S)-1,2-Diolein" Stitch 3.45E-03 1.00E+00 4.90E-02 5.37E-01 7 50 "MBP,DGKZ,GPAM,DGKD,NRGN,PRKCG,GNE" Drug CID000003894 lavendustin A Stitch 3.50E-03 1.00E+00 4.97E-02 5.45E-01 15 171 "RYR1,FOXM1,APBB1,FYN,CACNA1A,CACNA1E,CACNB2,HRH3,TLX1,PIK3CD,PRKACB,PRKCG,KCNMA1,RASGRF1,CACNG7" Disease C0036341 Schizophrenia DisGeNET Curated 1.20E-21 7.62E-18 7.62E-18 7.11E-17 156 1561 "MAG,SERPINA3,MAP6,ACHE,MBP,LGR4,RTN3,SYNDIG1,CSMD2,ADCYAP1R1,FABP7,ADORA1,PLA2G6,MOBP,MOG,SOX6,ANK3,FOLH1,APBA2,APC,NTNG1,DGKZ,BCAN,NLGN1,AQP4,SLC1A2,ZNF365,SLC1A6,MSRA,PKNOX2,SLC6A9,SHANK2,ASCL1,GPR153,CSPG5,MTR,ASTN1,B3GAT1,SNAP25,ATM,SNCB,NRG3,FYN,DKK3,GABBR1,MYT1L,TNIK,SOX5,SOX10,GAD2,CPLX2,FXYD6,NPAS3,NFASC,NCAM1,LMO3,GFAP,GFRA1,NEUROD1,MLC1,ARHGEF7,GLS,VAMP1,ASTN2,GNAS,WWC1,GPM6A,ACSL6,DDR1,CACNB2,TCF7L2,NRGN,PSD3,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,TF,OPCML,PTPN5,P2RX7,PAH,DAAM2,PAX6,TNFRSF1B,CDC42,PADI2,PCDH8,DCLK1,HRH3,MAGI1,PDE4B,PDYN,CHGA,CHRM1,CHRM4,CHRNB2,DLGAP3,NRXN1,NRXN2,PIK3CD,FADS2,FTO,SULT4A1,PLXNB3,PMP2,SLC25A27,BEST1,CP,POU3F2,ETNPPL,CRMP1,TENM4,PPP3CB,FEZ1,NCAN,CALY,CTNND2,MAPK8,NOS1AP,PSD,KIAA0513,RIMS3,BDNF-AS,CNIH3,LRP8,MAGI2,PTPRZ1,KCNH1,SV2A,SRGAP3,KCNJ10,ARNT2,PCDH15,NAV2,KCNN3,KCNQ2,DLG2,DLG3,KIF2A,CALN1,DNM2,SLC17A6,RASGRF1,RTN4,NUP214,USH1C,RGS10,EEF1A2,EN2,OLIG2" Disease C0005586 Bipolar Disorder DisGeNET Curated 5.34E-12 3.39E-08 1.70E-08 1.58E-07 77 730 "MAPT,ADCY2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK3,NTNG1,NLGN1,SLC1A2,SLC1A6,MTR,ASTN1,SNAP25,ATP1A2,NRG3,ATP1A3,FYN,GAD2,CPLX2,NPAS3,NCAM1,LMO3,GFAP,FGF17,MLC1,ARHGEF7,ASTN2,CACNA1A,CACNB2,TCF7L2,NRGN,CAMK2A,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIN1,GRM3,PTPN5,P2RX7,TLL2,PAH,TNR,DCLK1,SEZ6L,MAGI1,PDE4B,PDYN,PFKFB3,NRXN1,FADS2,FTO,POU3F2,ETNPPL,PTPA,TENM4,PPP3CB,FEZ1,NCAN,PRKCZ,CTNND2,PSD,BDNF-AS,MAGI2,KCNN3,KCNQ2,DLG2,DLG3,SLC17A6,DSCAM,RASGRF1,RTN4,RFX4" Disease C0036572 Seizures DisGeNET Curated 1.34E-11 8.54E-08 2.85E-08 2.66E-07 93 982 "ABAT,MAPT,ACHE,ADGRV1,EYA1,ARID1A,ADAR,RYR1,AGT,SCN3A,PLA2G6,ASIC4,FOXG1,AMPH,ANK1,APBB1,SESN3,NTNG1,DGKD,SLITRK3,AQP4,SLC1A2,SLC6A9,SLC8A3,MT3,CCDC88A,ASCL1,MTR,SMARCE1,ALDH4A1,ATM,ATP1A2,GABBR1,SOX10,GAD2,NCAM1,LMO3,GFAP,MLC1,ARHGEF7,ABCC8,GNAS,GNG3,CNTN2,CACNA1A,GRIA1,GRIA2,GRIK2,GRIN1,GRM3,CRB1,PAH,TNFRSF1B,PC,TNS1,SEZ6L,LGI1,PDYN,ADGRG1,HMGB1,CHRM1,CHRNB2,NRXN1,PIK3CD,PMS2,NSD2,CRMP1,MAPK10,PROX1,ANKS1B,PTCH1,DNAJC6,PLPPR1,MAGI2,KCNA1,KCNA2,KCNC1,KCNH1,SV2A,SRGAP3,KCNJ10,KCNJ11,ARNT2,KCNK2,PEX5,KCNQ2,KIF2A,GNE,L1CAM,RET,EEF1A2,BSCL2,RPE65" Disease C3714756 Intellectual Disability DisGeNET Curated 2.44E-10 1.55E-06 3.87E-07 3.61E-06 99 1131 "EPS8,MAPT,APC2,LGR4,EYA1,ARID1A,CLIP1,WAC,NLGN4X,SCN3A,PLA2G6,FOXG1,CDC42BPA,ANK1,ANK3,APC,NTNG1,ST3GAL3,SHANK2,ASCL1,MTR,SMARCE1,ALDH4A1,SNAP25,ATP1A2,MYT1L,SOX5,SOX10,EMC1,NPAS3,KIRREL3,ABCC8,GNAS,DDHD2,CAMTA1,CNDP1,NUDT21,CAMK2A,GRIA2,GRIK2,GRIK4,GRIN1,OMG,CRB1,MFSD2A,AIFM1,PAH,PAX6,PC,CDC42,TNR,RBFOX2,ADGRG1,TUB,HNRNPK,HEPACAM,NLGN3,CADM1,NRXN1,BEST1,ATCAY,NXPH1,POU3F2,PTPA,RGS6,FMN2,PRKCG,CTNND2,MAPK10,MASP1,ZBTB16,GON4L,ZNF385B,PTCH1,DNAJC6,KCNA2,KCNH1,SRGAP3,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,RALGDS,DSCAM,L1CAM,NUP214,RET,USH1C,RGR,JMJD1C,RGS7,EEF1A2,RLBP1,SLC4A10,ROM1,BSCL2,RPE65" Disease C0004352 Autistic Disorder DisGeNET Curated 6.62E-10 4.20E-06 8.41E-07 7.85E-06 66 644 "EPS8,ABAT,MBP,CSMD3,CLIP1,WAC,NLGN4X,AGT,SCN3A,FOXG1,ANK3,APBA2,APC,NTNG1,NLGN1,AQP4,SLC1A2,SHANK2,MTR,SNAP25,ATP2B2,GABBR1,GAD2,NCAM1,NDUFA5,ASTN2,ROBO3,CACNA1A,CACNB2,GRIA1,GRIA2,GRIK2,GRIK4,TF,SPX,PAH,PAX6,TNFRSF1B,PCDH9,CDH8,CDH10,PDE4B,CHRNB2,HEPACAM,NLGN3,CADM1,NRXN1,PIK3CD,CP,PLD5,CTNND2,MAPK8,PSD,RIMS3,ITGAV,CADM2,LRP8,CSDE1,STMN4,PTPRZ1,KCNMA1,DLG3,DSCAM,RASGRF1,JMJD1C,EN2" Disease C0233514 Abnormal behavior DisGeNET Curated 1.44E-09 9.16E-06 1.53E-06 1.43E-05 45 365 "MAP6,MAPT,TUBB4A,SEMA6A,ANK3,SHANK2,SNAP25,ATM,SOX5,GAD2,NPAS3,NCAM1,LMO3,GJB1,ARHGEF7,SYT4,CAMTA1,GPM6A,HAP1,GRIA1,GRIK2,GRIN1,GRM3,PAH,DCLK1,MAGI1,PDE4B,PDYN,CHRM4,NLGN3,DLGAP3,NRXN1,SULT4A1,FEZ1,CTNND2,NOS1AP,PSD,PSMD13,PLPPR4,PEX5,DLG3,ATN1,L1CAM,SLC6A15,OLIG2" Disease C0014544 Epilepsy DisGeNET Curated 7.36E-09 4.68E-05 6.68E-06 6.23E-05 84 962 "ABAT,MAPT,ADGRV1,ARID1A,MDM4,FABP7,SCN3A,PLA2G6,SEMA6A,FOXG1,ANK2,APBA2,SESN3,NTNG1,AQP4,SLC1A2,SLC6A9,CCDC88A,ASCL1,MTR,SMARCE1,ALDH4A1,ATM,ATP1A2,ATP1A3,GABBR1,SOX10,GFAP,MLC1,ABCC8,GNAS,CAMSAP2,CNTN2,CACNA1A,GRIA1,GRIA2,GRIK2,GRIN1,GRM3,CRB1,PTPN5,PAH,PAX6,PC,RBFOX2,LGI1,PDYN,ADGRG1,HMGB1,CHRM1,CHRNB2,NRXN1,PIK3CD,FTO,BEST1,PMS2,NSD2,PTPA,PTCH1,DNAJC6,MAGI2,KCNA1,KCNA2,KCNC1,KCNH1,SV2A,KCNJ10,KCNJ11,ARNT2,KCNK2,KCNMA1,PEX5,KCNQ2,KIF2A,SLC17A6,GOPC,GNE,L1CAM,RET,EEF1A2,SLC4A10,BSCL2,RPE65,SEZ6" Disease C0004936 Mental disorders DisGeNET Curated 2.74E-08 1.74E-04 2.17E-05 2.03E-04 39 321 "MAG,SLITRK1,ADCYAP1R1,TUBB4A,SEMA6A,ANK3,SNAP25,NPAS3,NCAM1,LMO3,GFAP,ARHGEF7,SYT4,ACSL6,CACNB2,NRGN,GRIA1,GRIK4,GRIN1,PAH,KCNK10,DCLK1,MAGI1,PDE4B,PDYN,CHRM4,NRXN1,FTO,SULT4A1,ATCAY,FEZ1,CTNND2,NOS1AP,PSD,PSMD13,BDNF-AS,PLPPR4,SLC6A15,OLIG2" Disease C0025362 Mental Retardation DisGeNET Curated 8.14E-08 5.17E-04 5.75E-05 5.36E-04 76 885 "MAPT,APC2,LGR4,EYA1,ARID1A,NLGN4X,SCN3A,PLA2G6,FOXG1,CDC42BPA,ANK1,ANK3,APC,NTNG1,SHANK2,ASCL1,MTR,SMARCE1,ALDH4A1,SNAP25,ATP1A2,MYT1L,SOX5,SOX10,NPAS3,ABCC8,GNAS,DDHD2,GRIK2,GRIK4,GRIN1,OMG,CRB1,AIFM1,PAH,PAX6,PC,CDC42,RBFOX2,ADGRG1,TUB,HNRNPK,HEPACAM,NLGN3,CADM1,NRXN1,BEST1,ATCAY,NXPH1,RGS6,CTNND2,MAPK10,MASP1,ZBTB16,ZNF385B,PTCH1,DNAJC6,SRGAP3,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,DSCAM,L1CAM,NUP214,RET,USH1C,RGR,EEF1A2,RLBP1,SLC4A10,ROM1,BSCL2,RPE65" Disease C0001973 "Alcoholic Intoxication, Chronic" DisGeNET Curated 2.15E-07 1.36E-03 1.36E-04 1.27E-03 43 402 "ABAT,MBP,DSCAML1,NLGN4X,TESK2,AGT,SEMA6A,MOBP,MOG,SGIP1,SLC1A2,PKNOX2,SLC6A9,TAGLN3,ASTN1,FYN,GABBR1,GAD2,NCAM1,LMO3,GFAP,ARHGEF7,LILRA1,NRDC,CAMK2A,GRIK3,GRIN1,GRM3,TF,CCKBR,CDH8,CDH10,PDE4B,PDYN,HMGB1,PIK3CD,FTO,CNIH3,LRP8,KCNN3,NKAIN1,ATN1,RFX4" Disease C0011570 Mental Depression DisGeNET Curated 3.21E-07 2.04E-03 1.80E-04 1.68E-03 53 554 "EYA1,CSMD2,NDRG2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK1,FOLH1,STK32C,AQP4,SLC1A2,MT3,MTR,SNAP25,ATM,ATP1A3,CPLX2,NCAM1,LMO3,GFAP,FGF17,NELL1,SLCO1C1,WWC1,GPM6A,GPR26,CAMK2A,GRIA1,GRID1,GRIK3,GRIN1,GRM3,TGFBR3,P2RX7,TNFRSF1B,LGI1,PDE4B,PDYN,PFKFB3,CHRNB2,NRXN1,FTO,NXPH1,MAPK8,NOS1AP,SIRPA,BDNF-AS,KCNK2,ATN1,ABCC9,SLC6A15,SLC4A10" Disease C0027765 nervous system disorder DisGeNET Curated 3.41E-07 2.17E-03 1.80E-04 1.68E-03 44 423 "MAPT,ACHE,FABP7,TUBB4A,PLA2G6,ASIC4,FOXG1,MOG,AQP4,SLC1A2,SHANK2,ASCL1,ARFGAP1,MTR,SNAP25,ATM,ATP1A2,ATP1A3,SOX10,CPLX2,GFAP,NEUROD1,VAMP1,CACNA1A,GRIA2,INA,LGI1,PDYN,HMGB1,FTO,COL9A2,ATCAY,CP,PNKD,HES5,PTHLH,SV2A,KCNQ2,DLG3,DNM2,L1CAM,RET,ATL1,EEF1A2" Disease C0002395 Alzheimer's Disease DisGeNET Curated 4.57E-07 2.90E-03 2.23E-04 2.08E-03 128 1825 "SERPINA3,MAPT,ACHE,APC2,MBP,RTN3,IL17D,ECSIT,NDRG2,ADCY2,ADD3,SORCS1,AGT,FGF1,PLA2G6,SEMA6A,SLC30A10,MOG,FOXM1,AMPH,SFPQ,ANK1,FOLH1,PKP4,SH3GL2,APBA2,APBB1,APC,BCAN,SYBU,NLGN1,ST8SIA1,AQP4,SLC1A2,MADD,MSRA,SLC8A3,MT3,SHANK2,PDE8B,SCG3,MTR,SORCS3,SNAP25,ATM,SNCB,NRG3,FYN,WDTC1,NMNAT2,CPLX2,FXYD6,LMO3,NDUFA5,GFAP,GFRA1,RND1,NFIA,ARHGEF7,VAMP1,PCDH11X,ASTN2,WWC1,DDR1,NPPA,NRDC,NRGN,HAP1,AZIN2,PTBP2,CAMK2A,BRSK2,GRIA1,GRIA2,GRIK4,GRIN1,TF,OLR1,PTPN5,P2RX7,ATG4C,PAX6,TNFRSF1B,PC,CDC42,HRH3,PDYN,NTSR2,PFKFB3,CHRM1,CHRNB2,TMEFF2,JAM2,HPCA,SERPINE2,PIK3CD,FTO,SLC25A27,BEST1,PRRX1,ATCAY,CP,POU3F4,CRMP1,PTPA,SNCAIP,VCAN,PRKACB,CTNND2,MAPK8,MAPK10,ECE2,MASP1,KLK6,PSD,ANKS1B,LRRTM3,PTCH1,SV2A,KCNMA1,DLG3,DNM2,ATN1,ABCC9,NUP214,RET,EEF1A2,ELAVL4" Disease C0004114 Astrocytoma DisGeNET Curated 6.20E-07 3.93E-03 2.81E-04 2.62E-03 63 721 "ACHE,MBP,WLS,MDM4,NDRG2,F3,FABP7,CHST15,SEMA6A,FOLH1,APC,AQP4,SLC1A2,ASCL1,DLL3,B3GAT1,ATM,DKK3,WDTC1,SOX10,NPAS3,NCAM1,ALDH1L1,GPR162,GFAP,MLC1,ARHGEF7,NKX2-2,CAMTA1,BTRC,CNTN2,TCF7L2,DIRAS1,AZIN2,PSD3,P2RX7,AIFM1,NEURL1,PAX6,CDC42,LGI1,TPM3,PDE3B,PFKFB3,SERPINE2,PIK3CD,FTO,VAV2,RGS6,CSF3R,VCAN,MAPK8,HES5,KLK6,SIRPA,PTHLH,PTPRZ1,PID1,DNM2,ATN1,RASGRF1,BSCL2,OLIG2" Disease C1510586 Autism Spectrum Disorders DisGeNET Curated 7.87E-07 5.00E-03 3.33E-04 3.11E-03 44 436 "FABP7,NLGN4X,FOXG1,MOG,ANK3,APBA2,APC,NLGN1,SHANK2,SNAP25,ATP2B2,SOX5,GFAP,KIRREL3,ASTN2,CACNA1A,CACNB2,GRIK4,PAH,PAX6,PCDH9,CDH8,SEZ6L,NLGN3,CADM1,NRXN1,NRXN2,PIK3CD,NXPH1,POU3F2,CTNND2,MAPK10,PSD,LRRTM3,BDNF-AS,KCNJ10,ARNT2,PCDH15,DPP6,L1CAM,JMJD1C,CBLN2,ROM1,EN2" Disease C0011581 Depressive disorder DisGeNET Curated 1.89E-06 1.20E-02 7.49E-04 6.99E-03 60 697 "MAPT,EYA1,CSMD2,NDRG2,ADCYAP1R1,FABP7,AGT,PLA2G6,ANK1,FOLH1,STK32C,AQP4,SLC1A2,MT3,MTR,SNAP25,ATM,ATP1A3,CPLX2,NCAM1,LMO3,GFAP,FGF17,NELL1,SLCO1C1,GNAS,WWC1,GPM6A,GPR26,CAMK2A,GRIA1,GRID1,GRIK3,GRIN1,GRM3,TGFBR3,P2RX7,PAH,TNFRSF1B,LGI1,PDE4B,PDYN,CHRNB2,CADM1,NRXN1,FTO,PMS2,NXPH1,CP,SNCAIP,PRKCG,MAPK8,NOS1AP,SIRPA,BDNF-AS,KCNK2,ATN1,ABCC9,SLC6A15,SLC4A10" Disease C0728829 Congenital pes cavus DisGeNET Curated 2.50E-06 1.59E-02 9.33E-04 8.71E-03 16 89 "ATP1A3,SOX10,MYH7,KIF1B,SPART,GJB1,VAMP1,AIFM1,TPM3,DNAJC6,PEX5,DNM2,L1CAM,RET,ATL1,BSCL2" Disease C0027819 Neuroblastoma DisGeNET Curated 2.89E-06 1.84E-02 1.02E-03 9.53E-03 117 1689 "MAPT,ACHE,EXTL1,CEND1,MEG3,ATAT1,ARID1A,WLS,MDM4,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,FABP7,PLA2G6,SEMA6A,FOXM1,SFPQ,ANK2,ITSN1,APC,URGCP,SLC2A5,MADD,NBPF1,MSRA,ASCL1,SCG3,ASPH,B3GAT1,SNAP25,ATM,SNCB,DKK3,WDTC1,B4GALNT1,KIF1B,GART,DNER,NCAM1,LMO3,MIR100HG,BCL2L2,SMOC1,GFAP,NEUROD1,AJAP1,NFIA,ARHGEF7,NHLH1,NKX2-2,GNAS,CAMTA1,UNC5D,BTRC,WWC1,PRUNE2,NPPA,NEU4,NRDC,NRGN,PTBP2,CAMK2G,GRIA2,PTPN5,TGFBR3,P2RX7,CD81,CDK11B,TNFRSF1B,CDC42,DCLK1,LGI1,TPM3,PDYN,HMGB1,CHGA,DUSP26,SERPINE2,CADM1,NEGR1,PIK3CD,HPR,FTO,SLC25A27,PMS2,CRMP1,PTPA,SNCAIP,CSF3R,CHD5,RBPJ,PRKCZ,SLC45A1,MAPK8,HES5,PROX1,ACY3,PTCH1,ITGAV,PTHLH,PRDM2,LRP8,STMN4,PTPRD,SRGAP3,ARNT2,NAV2,ATN1,RASGRF1,PAK5,L1CAM,NUP214,RET,VANGL2,LMO1,ELAVL4" Disease C0700095 Central neuroblastoma DisGeNET BeFree 4.38E-06 2.78E-02 1.46E-03 1.37E-02 113 1631 "MAPT,ACHE,EXTL1,CEND1,MEG3,ATAT1,ARID1A,WLS,MDM4,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,FABP7,PLA2G6,SEMA6A,FOXM1,SFPQ,ANK2,ITSN1,APC,URGCP,MADD,NBPF1,MSRA,ASCL1,SCG3,ASPH,B3GAT1,SNAP25,ATM,SNCB,DKK3,WDTC1,B4GALNT1,KIF1B,GART,DNER,NCAM1,LMO3,MIR100HG,BCL2L2,SMOC1,GFAP,NEUROD1,AJAP1,NFIA,ARHGEF7,NHLH1,NKX2-2,GNAS,CAMTA1,UNC5D,BTRC,WWC1,PRUNE2,NPPA,NEU4,NRDC,NRGN,PTBP2,CAMK2G,GRIA2,PTPN5,TGFBR3,P2RX7,CD81,CDK11B,TNFRSF1B,CDC42,DCLK1,LGI1,TPM3,PDYN,HMGB1,CHGA,DUSP26,SERPINE2,CADM1,NEGR1,PIK3CD,HPR,FTO,SLC25A27,CRMP1,PTPA,SNCAIP,CSF3R,CHD5,SLC45A1,MAPK8,HES5,PROX1,ACY3,PTCH1,ITGAV,PTHLH,PRDM2,LRP8,STMN4,PTPRD,SRGAP3,ARNT2,NAV2,ATN1,RASGRF1,PAK5,L1CAM,NUP214,RET,VANGL2,LMO1,ELAVL4" Disease C1269683 Major Depressive Disorder DisGeNET Curated 7.26E-06 4.61E-02 2.31E-03 2.15E-02 46 505 "MAG,ACHE,MDM4,ADAR,ADCYAP1R1,MOG,ANK3,SLC1A2,SLC1A6,SNAP25,GABBR1,MYT1L,GAD2,NPAS3,NCAM1,GFAP,NELL1,GPM6A,NRGN,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK4,GRM3,P2RX7,TNFRSF1B,PDE4B,PDYN,PFKFB3,FADS2,FTO,NCAN,CTNND2,NRSN1,ZBTB16,PSMD13,BDNF-AS,LRP8,NTM,KCNK2,DLG2,DLG3,OLIG1,SLC17A6,SLC6A15" Disease C0026650 Movement Disorders DisGeNET Curated 1.27E-05 8.06E-02 3.84E-03 3.58E-02 20 147 "MAPT,ACHE,FGF14,ASIC4,FOXG1,NTNG1,PDE8B,ATP1A2,ATP1A3,CACNA1A,GRIN1,PAX6,LGI1,PDYN,CP,PNKD,KCNA1,PEX5,GOPC,ATL1" Disease C0004134 Ataxia DisGeNET Curated 1.73E-05 1.10E-01 4.99E-03 4.65E-02 24 201 "PLA2G6,FGF14,SEMA6A,ANK1,SNAP25,ATM,ATP1A3,GJB1,VAMP1,CAMTA1,CACNA1A,AIFM1,PDYN,ATCAY,CP,RGS6,PRKCG,KCNA1,KCNA2,KCND3,KCNJ10,KCNN3,ATN1,UEVLD" Disease C0041696 Unipolar Depression DisGeNET Curated 2.10E-05 1.33E-01 5.79E-03 5.41E-02 39 418 "MDM4,ADAR,ADCYAP1R1,ANK3,SLC1A2,SLC1A6,SNAP25,GABBR1,MYT1L,GAD2,NPAS3,NCAM1,GFAP,NELL1,WWC1,GPM6A,NRGN,CAMK2A,GRIA1,GRIA2,GRIA4,GRIK4,P2RX7,TNFRSF1B,PDE4B,PDYN,PFKFB3,FTO,NCAN,CTNND2,NRSN1,ZBTB16,LRP8,NTM,KCNK2,DLG2,DLG3,SLC17A6,SLC6A15" Disease C0751396 Well Differentiated Oligodendroglioma DisGeNET BeFree 2.19E-05 1.39E-01 5.80E-03 5.41E-02 21 165 "ACLY,MBP,ADCYAP1R1,APC,BCAN,ASCL1,SNCB,MYT1L,SOX10,GFAP,AJAP1,NKX2-2,CNTN2,INA,TNR,PDE3B,HMGB1,RGS6,OLIG1,ATN1,OLIG2" Disease C0040822 Tremor DisGeNET Curated 2.44E-05 1.55E-01 6.20E-03 5.79E-02 23 192 "MAPT,ACHE,ADAR,ADORA1,PLA2G6,SLC30A10,ATM,GABBR1,GFAP,GJB1,NEUROD1,CNTN2,CACNA1A,PAH,CHRM4,HPCA,CP,RGS6,DNAJC6,KCNA1,KCNA2,KCNC1,BSCL2" Disease C0040485 Torticollis DisGeNET Curated 2.74E-05 1.74E-01 6.69E-03 6.24E-02 7 21 "ATP1A3,CACNA1A,ATP13A2,HPCA,CP,PNKD,DNM2" Disease C0028945 oligodendroglioma DisGeNET Curated 2.88E-05 1.83E-01 6.78E-03 6.32E-02 21 168 "ACLY,MBP,ADCYAP1R1,APC,BCAN,ASCL1,SNCB,MYT1L,SOX10,GFAP,AJAP1,NKX2-2,CNTN2,INA,TNR,PDE3B,HMGB1,RGS6,OLIG1,ATN1,OLIG2" Disease C0013362 Dysarthria DisGeNET Curated 3.40E-05 2.16E-01 7.70E-03 7.19E-02 23 196 "MAPT,PLA2G6,SLC30A10,PDE8B,SNAP25,ATM,ATP1A2,ATP1A3,SPART,GJB1,VAMP1,DDHD2,CAMTA1,CACNA1A,PDYN,HPCA,CP,PNKD,SNCAIP,PRKCG,DNAJC6,KCNA1,KCND3" Disease C1142166 Brugada Syndrome (disorder) DisGeNET Curated 4.28E-05 2.72E-01 9.27E-03 8.65E-02 10 47 "KCNIP2,SCN4B,FGF14,SCN3B,MYH7,CACNB2,NOS1AP,KCND3,KCNK1,ATN1" Disease C0003467 Anxiety DisGeNET Curated 4.38E-05 2.78E-01 9.27E-03 8.65E-02 39 432 "ASIC1,MAPT,ACHE,EYA1,NDRG2,ADCYAP1R1,FABP7,ADORA1,AGT,ASIC4,ANK3,FOLH1,APC,SLC1A2,MT3,ATM,NRG3,ATP1A3,FYN,SOX5,GAD2,FGF17,GNAS,CACNA1A,GPR26,GRIA1,GRIA2,CCKBR,PAH,PDE4B,NLGN3,DLGAP3,FTO,PMS2,ACBD5,CTNND2,BDNF-AS,DNM2,FGFBP3" Disease C1720037 Supranuclear gaze palsy DisGeNET Curated 6.11E-05 3.88E-01 1.25E-02 1.17E-01 4 6 "MAPT,PLA2G6,VAMP1,ATP13A2" Disease C0003469 Anxiety Disorders DisGeNET Curated 7.95E-05 5.05E-01 1.58E-02 1.47E-01 35 382 "ASIC1,ACHE,EYA1,NDRG2,ADCYAP1R1,FABP7,ADORA1,AGT,ASIC4,ANK3,FOLH1,APC,SLC1A2,MT3,ATM,NRG3,FYN,GAD2,NCAM1,GPR26,GRIA1,GRIA2,CCKBR,P2RX7,PDE4B,CHRNB2,NLGN3,DLGAP3,FTO,ACBD5,CTNND2,BDNF-AS,MAGI2,DNM2,FGFBP3" Disease C0338656 Impaired cognition DisGeNET Curated 9.20E-05 5.84E-01 1.77E-02 1.65E-01 50 625 "SERPINA3,MAPT,ACHE,RTN3,ADD3,PLA2G6,FGF14,FOXG1,AMPH,ANK3,AQP4,SLC1A2,SLC6A9,SHANK2,MTR,SNAP25,NRG3,FYN,GAD2,NMNAT2,CPLX2,SPART,GFAP,GJB1,NFIA,ABCC8,ASTN2,GNAS,CNTN2,WWC1,CACNA1A,CAMK2A,GRIA2,GRM3,ATP13A2,AIFM1,DCLK1,HRH3,ARHGAP22,PIK3CD,FTO,SULT4A1,CRMP1,CTNND2,MAPK8,MAGI2,PEX5,KCNQ2,SLC6A15,EEF1A2" Disease C0596298 Cerebrovascular Occlusion DisGeNET BeFree 1.01E-04 6.40E-01 1.85E-02 1.73E-01 3 3 "ASCL1,GFAP,KCNK10" Disease C0033975 Psychotic Disorders DisGeNET Curated 1.02E-04 6.47E-01 1.85E-02 1.73E-01 30 311 "SERPINA3,MAPT,RTN3,PLA2G6,SEMA6A,ANK3,SLC1A2,SLC6A9,B3GAT1,SNAP25,CPLX2,NPAS3,ARHGEF7,PCDH11X,GNAS,WWC1,CACNA1A,ACSL6,NRGN,GRIK3,GRIK4,GRIN1,GRM3,PAH,FTO,TENM4,FEZ1,NRSN1,PAK5,OLIG2" Disease C0002736 Amyotrophic Lateral Sclerosis DisGeNET Curated 1.08E-04 6.84E-01 1.90E-02 1.77E-01 50 629 "SERPINA3,MAPT,SYT9,ATAT1,ADAR,ADARB2,CLIP1,CDC7,MOBP,AMPH,SFPQ,AQP4,SLC1A2,CCDC88A,SNAP25,WDTC1,KIF1B,GART,NCAM1,GFAP,GFRA1,GJB1,ARHGEF7,GRIA1,GRIA2,GRM3,INA,P2RX7,TNFRSF1B,TNS1,PCSK2,PRMT8,CHGA,HNRNPK,PTPA,OSBPL3,MAPK8,KCNJ10,KCNK2,DNM2,SLC17A6,DPP6,RASGRF1,RTN4,CAMK1G,NUP214,RET,ATL1,BSCL2,OLIG2" Disease C1865322 "MIGRAINE, FAMILIAL HEMIPLEGIC, 2" DisGeNET Curated 1.37E-04 8.72E-01 2.29E-02 2.13E-01 4 7 "ATP1A2,ATP1A3,CACNA1A,KCNN3" Disease C0746408 mass lesion DisGeNET BeFree 1.37E-04 8.72E-01 2.29E-02 2.13E-01 4 7 "GRIA1,GRIA2,GRIN1,GRM3" Disease C0023520 Leukodystrophy DisGeNET Curated 1.40E-04 8.92E-01 2.29E-02 2.13E-01 13 86 "MAG,ABAT,PLA2G6,SOX10,GFAP,GJB1,MLC1,GPM6B,HEPACAM,PTHLH,OLIG1,ATN1,OLIG2" Disease C1843921 Postural instability DisGeNET Curated 1.48E-04 9.39E-01 2.35E-02 2.19E-01 6 19 "PLA2G6,SLC30A10,ATP1A3,ATP13A2,SNCAIP,DNAJC6" Disease C0004238 Atrial Fibrillation DisGeNET Curated 1.72E-04 1.00E+00 2.67E-02 2.49E-01 24 232 "ACTN2,ARID1A,F3,AGT,SCN4B,ANK2,MSRA,SLN,MTR,ATM,SCN3B,SOX5,MYH7,ADAM15,NPPA,CACNB2,OLR1,PRRX1,CP,RGS6,KCNK1,KCNN3,DTNA,ABCC9" Disease C1843367 Poor school performance DisGeNET Curated 2.29E-04 1.00E+00 3.31E-02 3.09E-01 50 649 "APC2,EYA1,ARID1A,PLA2G6,FOXG1,ANK1,ANK3,NTNG1,ASCL1,MTR,SMARCE1,ALDH4A1,ATP1A2,MYT1L,SOX5,SOX10,ABCC8,GNAS,DDHD2,GRIK2,GRIN1,CRB1,AIFM1,PAH,PAX6,PC,ADGRG1,TUB,HNRNPK,BEST1,MAPK10,MASP1,ZBTB16,PTCH1,DNAJC6,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,L1CAM,RET,USH1C,RGR,EEF1A2,RLBP1,ROM1,BSCL2,RPE65" Disease C0423903 Low intelligence DisGeNET Curated 2.29E-04 1.00E+00 3.31E-02 3.09E-01 50 649 "APC2,EYA1,ARID1A,PLA2G6,FOXG1,ANK1,ANK3,NTNG1,ASCL1,MTR,SMARCE1,ALDH4A1,ATP1A2,MYT1L,SOX5,SOX10,ABCC8,GNAS,DDHD2,GRIK2,GRIN1,CRB1,AIFM1,PAH,PAX6,PC,ADGRG1,TUB,HNRNPK,BEST1,MAPK10,MASP1,ZBTB16,PTCH1,DNAJC6,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,L1CAM,RET,USH1C,RGR,EEF1A2,RLBP1,ROM1,BSCL2,RPE65" Disease C4020876 Dull intelligence DisGeNET Curated 2.29E-04 1.00E+00 3.31E-02 3.09E-01 50 649 "APC2,EYA1,ARID1A,PLA2G6,FOXG1,ANK1,ANK3,NTNG1,ASCL1,MTR,SMARCE1,ALDH4A1,ATP1A2,MYT1L,SOX5,SOX10,ABCC8,GNAS,DDHD2,GRIK2,GRIN1,CRB1,AIFM1,PAH,PAX6,PC,ADGRG1,TUB,HNRNPK,BEST1,MAPK10,MASP1,ZBTB16,PTCH1,DNAJC6,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,L1CAM,RET,USH1C,RGR,EEF1A2,RLBP1,ROM1,BSCL2,RPE65" Disease C0917816 Mental deficiency DisGeNET Curated 2.47E-04 1.00E+00 3.39E-02 3.16E-01 50 651 "APC2,EYA1,ARID1A,PLA2G6,FOXG1,ANK1,ANK3,NTNG1,ASCL1,MTR,SMARCE1,ALDH4A1,ATP1A2,MYT1L,SOX5,SOX10,ABCC8,GNAS,DDHD2,GRIK2,GRIN1,CRB1,AIFM1,PAH,PAX6,PC,ADGRG1,TUB,HNRNPK,BEST1,MAPK10,MASP1,ZBTB16,PTCH1,DNAJC6,KCNJ10,KCNJ11,PEX5,KCNQ2,DLG3,DPP6,L1CAM,RET,USH1C,RGR,EEF1A2,RLBP1,ROM1,BSCL2,RPE65" Disease C0007758 Cerebellar Ataxia DisGeNET Curated 2.50E-04 1.00E+00 3.39E-02 3.16E-01 38 453 "ACER3,ACHE,PLA2G6,FGF14,SEMA6A,ANK1,SNAP25,ATM,ATP1A2,ATP1A3,FYN,SOX10,GFAP,GJB1,MLC1,ABCC8,VAMP1,CAMTA1,CACNA1A,AIFM1,PAX6,LGI1,PDYN,NSD2,ATCAY,CP,RGS6,PRKCG,KCNA1,KCNA2,KCND3,KCNJ10,KCNN3,PEX5,ATN1,USH1C,BSCL2,UEVLD" Disease C0040517 Gilles de la Tourette syndrome DisGeNET Curated 2.51E-04 1.00E+00 3.39E-02 3.16E-01 13 91 "SLITRK1,ADORA1,NLGN4X,MOG,APBA2,LMO3,ROBO3,DLGAP3,NRXN1,OLIG1,DPP6,CBLN2,OLIG2" Disease C0270862 Hemiplegic migraine DisGeNET BeFree 2.65E-04 1.00E+00 3.50E-02 3.27E-01 4 8 "ATP1A2,ATP1A3,CACNA1A,PNKD" Disease C0011168 Deglutition Disorders DisGeNET Curated 3.52E-04 1.00E+00 4.53E-02 4.23E-01 17 145 "MAPT,RYR1,PLA2G6,PDE8B,ATP1A3,MYH7,GJB1,VAMP1,DDHD2,CACNA1A,GUCY1A1,TPM3,HPCA,PNKD,SNCAIP,PRKCG,KCND3" Disease C1535926 Neurodevelopmental Disorders DisGeNET Curated 3.57E-04 1.00E+00 4.53E-02 4.23E-01 16 132 "MEG3,ADCYAP1R1,FOXG1,ANK3,NTNG1,SHANK2,NRG3,ATP1A3,ASTN2,CACNA1A,TCF7L2,NRXN1,KCNA2,DLG2,L1CAM,EEF1A2" Disease C0339526 Autosomal recessive retinitis pigmentosa DisGeNET BeFree 3.94E-04 1.00E+00 4.82E-02 4.50E-01 9 50 "ADGRV1,SLC7A14,NEUROD1,CRB1,TUB,USH1C,RLBP1,ROM1,RPE65" Disease C0085648 Synovial Cyst DisGeNET BeFree 4.02E-04 1.00E+00 4.82E-02 4.50E-01 21 202 "MAPT,ACHE,MBP,IL17D,FGF1,MOG,NLGN1,DKK3,SOX10,GAD2,GFAP,GFRA1,NEUROD1,PRUNE2,CPT1C,CRMP1,CHD5,PTHLH,KCNA2,RET,RGR" Disease C1970943 MAJOR AFFECTIVE DISORDER 4 DisGeNET Curated 4.10E-04 1.00E+00 4.82E-02 4.50E-01 11 72 "ANK3,NCAM1,MLC1,GRM3,P2RX7,DCLK1,MAGI1,PRKCZ,MAGI2,KCNN3,KCNQ2" Disease C1970945 MAJOR AFFECTIVE DISORDER 6 DisGeNET Curated 4.10E-04 1.00E+00 4.82E-02 4.50E-01 11 72 "ANK3,NCAM1,MLC1,GRM3,P2RX7,DCLK1,MAGI1,PRKCZ,MAGI2,KCNN3,KCNQ2" GO: Molecular Function GO:0008092 cytoskeletal protein binding 5.20E-23 1.39E-19 1.39E-19 1.17E-18 281 886 "ACTN1,ACTN2,FMNL2,ADD1,ADD2,ADD3,ERMN,ADORA2A,MRTFA,KIF6,BIN1,ANK1,ANK2,ANK3,MYH7B,APBB1,APC,EPB41L5,GAS7,SHTN1,SHROOM2,SPTBN4,MARK4,ATP1A1,KIF1A,PROM1,CDK5R1,DST,WASF1,CDK5R2,CACNA1D,CACNB2,CALM1,CAMK2B,CAMK2D,CAPN3,HIP1R,SPAG9,PRC1,KRIT1,FMNL3,ARHGEF2,MAGI1,CFL2,RAB3C,CLTC,CNN3,PICK1,AKAP5,MYRIP,CRMP1,CLIP3,FEZ1,ARHGEF10,MICAL2,SIPA1L1,PHACTR3,KATNAL2,KIF26A,AIF1L,DBN1,JAKMIP2,KLHL3,BLOC1S6,FBXO25,KIF19,RAB39B,DMD,DYNC1I1,DNM2,DPYSL2,ABI1,DYRK1A,USH1C,KLHL5,EGFR,ABI2,SORBS3,EML1,EPB41,EPB41L1,EPB41L2,DMTN,MTSS1L,GPHN,EPS8,NCALD,APC2,RCSD1,KATNAL1,ADGRV1,CORO2B,DLC1,FER,FGF13,BAIAP2,CAMSAP1,CAP2,EVL,FLNC,SGIP1,DCTN2,DPYSL4,SORBS1,PDLIM5,STAU2,TPPP3,BRSK1,ABLIM2,FYN,NEK6,IQGAP2,DISC1,WASF3,MYOZ2,TUBGCP4,PPARGC1A,GNAS,PSRC1,STMN2,TPPP,GRIA1,PTPRT,GSN,KIF3A,FRMD5,PACSIN2,FRMD3,GABARAPL2,SYNPO,AGBL5,HNRNPK,HPCA,HSP90AA1,ATCAY,MYLK2,SCIN,KCNA2,KCNC1,KCNJ11,KCNMA1,KCNN2,KCNQ2,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,KTN1,STMN1,PACRG,MAP2,MAP4,MAP6,MAPT,KCTD6,MID1,DBNL,JAKMIP3,BLOC1S2,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,NEFM,NEFH,NF1,NRCAM,NUMA1,OGG1,OPHN1,SNTG1,PDE4B,TMOD2,SSH1,ANLN,CCSER2,JAKMIP1,PLEC,FXYD1,SPATA6,EPB41L4B,PACSIN1,PPP5C,MAPK8,BCAS3,PTK2,PXK,PTPRN,RAB3A,RAD51D,RDX,TTLL7,KIF7,MYH14,KIRREL1,MAP6D1,LRRK2,CLIP1,AP1AR,S100B,KIF27,SGK1,KIF21A,PPP1R9A,KIF16B,MYO18A,FHOD3,SYBU,CLSTN1,ABLIM3,SMTN,PKNOX2,SLC8A1,SIRT2,CCDC88A,CDK5RAP2,MYH15,LIMCH1,SNAP25,SNCB,SNCA,KIF13A,PALLD,MYO16,KIF21B,SPTAN1,SPTB,KIF1B,CLASP2,ITPRID2,EPB41L3,MAPK8IP3,MPRIP,STX1A,FGD4,SYNE2,SYN1,ARC,COBL,MTCL1,CAMSAP2,PDLIM2,AGTPBP1,KLHL4,TRIM2,CLASP1,SYNE1,OBSL1,TIAM1,TMOD1,DAAM2,TNNT1,TNS1,TPM1,TPM2,TPM3,TPM4,SYNPO2,NEIL2,RUSC1,PLEKHH2,MICAL1,WIPF1,CLIP2,KLC2,FMN2,REEP1,DPYSL5,SPIRE1,LRP8,STMN4,WIPF2,ACTR3B,IFT88" GO: Molecular Function GO:0022836 gated channel activity 1.42E-17 3.79E-14 1.89E-14 1.60E-13 126 331 "KCNH8,ASIC2,ASIC1,KCNT1,KCNAB2,SHROOM2,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,CLCN3,CLCN4,CNGA3,CYBB,DLG3,DLG4,GRIN3A,CACNG7,KCNMB2,NCALD,CACNG3,CACNG2,PTK2B,HVCN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,HCN1,P2RX7,KCNK10,NALCN,TMEM38A,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,RASA3,SNAP25,SCN3B,ABCC8,ANO4,TPCN2,TRPC3,KCNE5,ANO5,BEST1,KCNK12,KCNT2,SLC17A7,KCNAB1,TMEM63C,JPH3" GO: Molecular Function GO:0005216 ion channel activity 1.74E-16 4.65E-13 1.55E-13 1.31E-12 148 424 "TTYH1,KCNH8,ASIC2,ASIC1,SLC24A4,KCNT1,KCNAB2,SHROOM2,AQP6,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,CNGA3,CYBB,DLG3,DLG4,GRIN3A,ABCC9,CACNG7,KCNMB2,NCALD,CACNG3,CACNG2,PTK2B,TMEM175,HVCN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,FXYD7,FXYD6,HCN1,P2RX7,KCNK10,PDE2A,BEST3,NALCN,PKD1,TMEM38A,FXYD1,SLC26A11,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,RASA3,SNAP25,SCN3B,MLC1,ABCC8,ANO4,TPCN2,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,BEST1,KCNK12,KCNT2,SLC26A10,SLC17A7,KCNAB1,TMEM63C,JPH3" GO: Molecular Function GO:0022838 substrate-specific channel activity 2.97E-16 7.92E-13 1.98E-13 1.68E-12 151 438 "TTYH1,KCNH8,ASIC2,ASIC1,SLC24A4,KCNT1,KCNAB2,SHROOM2,AQP4,AQP6,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,CNGA3,CYBB,DLG3,DLG4,GRIN3A,ABCC9,CACNG7,KCNMB2,NCALD,CACNG3,CACNG2,PTK2B,TMEM175,HVCN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,AQP11,FXYD7,FXYD6,HCN1,P2RX7,KCNK10,PDE2A,BEST3,NALCN,PKD1,TMEM38A,FXYD1,SLC26A11,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,RASA3,SLC14A1,SNAP25,SCN3B,MLC1,ABCC8,ANO4,TPCN2,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,BEST1,KCNK12,KCNT2,SLC26A10,SLC17A7,KCNAB1,TMEM63C,JPH3" GO: Molecular Function GO:0046873 metal ion transmembrane transporter activity 9.26E-15 2.47E-11 4.28E-12 3.62E-11 144 426 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,KCNT1,KCNAB2,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KCNAB3,CACNA2D2,ASIC3,SLC24A2,CNGA3,SLC4A7,SLC32A1,GRIN3A,SLC12A6,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,ATP13A4,TMEM175,ATP2C1,KCNMB4,GPM6A,GRIN1,CACFD1,GRM7,IL1RAPL1,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,SLC11A2,HCN1,KCNK10,PDE2A,SLC10A4,NALCN,PKD1,TMEM38A,CNNM2,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A4,SLC20A2,SNAP25,SCN3B,ABCC8,TPCN2,TF,TRPC1,TRPC3,TRPM2,KCNE5,SLC13A3,KCNK12,KCNT2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,SLC39A12,JPH3" GO: Molecular Function GO:0015267 channel activity 9.63E-15 2.57E-11 4.28E-12 3.62E-11 155 470 "TTYH1,KCNH8,ASIC2,ASIC1,SLC24A4,KCNT1,KCNAB2,SHROOM2,AQP4,AQP6,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,CNGA3,CYBB,TOMM20,DLG3,DLG4,GRIN3A,ABCC9,CACNG7,KCNMB2,NCALD,CACNG3,CACNG2,PTK2B,TOMM40L,TMEM175,HVCN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GJB1,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,AQP11,FXYD7,FXYD6,HCN1,P2RX7,KCNK10,PDE2A,BEST3,NALCN,PKD1,TMEM38A,FXYD1,SLC26A11,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,RASA3,SLC14A1,SNAP25,SCN3B,MLC1,ABCC8,ANO4,TPCN2,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,BEST1,KCNK12,KCNT2,SLC26A10,SLC17A7,KCNAB1,TMEM63C,GJC2,JPH3" GO: Molecular Function GO:0022803 passive transmembrane transporter activity 1.18E-14 3.15E-11 4.49E-12 3.80E-11 155 471 "TTYH1,KCNH8,ASIC2,ASIC1,SLC24A4,KCNT1,KCNAB2,SHROOM2,AQP4,AQP6,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,CNGA3,CYBB,TOMM20,DLG3,DLG4,GRIN3A,ABCC9,CACNG7,KCNMB2,NCALD,CACNG3,CACNG2,PTK2B,TOMM40L,TMEM175,HVCN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GJB1,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,AQP11,FXYD7,FXYD6,HCN1,P2RX7,KCNK10,PDE2A,BEST3,NALCN,PKD1,TMEM38A,FXYD1,SLC26A11,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,RASA3,SLC14A1,SNAP25,SCN3B,MLC1,ABCC8,ANO4,TPCN2,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,BEST1,KCNK12,KCNT2,SLC26A10,SLC17A7,KCNAB1,TMEM63C,GJC2,JPH3" GO: Molecular Function GO:0005516 calmodulin binding 2.17E-13 5.77E-10 7.22E-11 6.11E-10 78 190 "ADCY8,ADD1,ADD2,ADD3,PLA2G6,CASK,ATP2B1,ATP2B2,ATP2B3,CACNA1A,CAMK2A,CAMK2B,CAMK2D,CAMK2G,USP6,CNN3,AKAP5,CTH,DAPK1,EGFR,EPB41,CAMSAP1,CAMKK2,ARPP21,IQGAP2,GAP43,GRIN1,GRM7,MYLK2,ITPKA,ITPKB,KCNH1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MAP2,MAP6,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,NOS1,NRGN,PDE1A,PDE1C,PDE1B,PHKG1,CAMKV,PIK3R1,STRN3,PPP3CA,PPP3CB,PPP3CC,CEP97,RASGRF2,RGS4,RIT2,MYH14,MAP6D1,RYR1,RYR3,SCN3A,SLC8A2,SLC8A1,SLC8A3,CDK5RAP2,MYH15,ENKUR,SPTAN1,PLCB1,SYT1,CAMSAP2,TJP1,CAMK1G" GO: Molecular Function GO:0022843 voltage-gated cation channel activity 1.74E-12 4.64E-09 5.15E-10 4.36E-09 62 141 "KCNH8,KCNT1,KCNAB2,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KCNAB3,CACNA2D2,CNGA3,CACNG7,CACNG3,CACNG2,HVCN1,GRIK1,GRIN1,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,HCN1,KCNIP2,RYR1,SNAP25,ABCC8,TPCN2,KCNE5,KCNT2,KCNAB1" GO: Molecular Function GO:0005261 cation channel activity 2.40E-12 6.40E-09 6.08E-10 5.15E-09 107 306 "KCNH8,ASIC2,ASIC1,SLC24A4,KCNT1,KCNAB2,SHROOM2,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,SLC24A2,CNGA3,GRIN3A,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,TMEM175,HVCN1,KCNMB4,GPM6A,GRIK1,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,HCN1,P2RX7,KCNK10,PDE2A,NALCN,PKD1,TMEM38A,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,RASA3,SNAP25,SCN3B,ABCC8,TPCN2,TRPC1,TRPC3,TRPM2,KCNE5,KCNK12,KCNT2,KCNAB1,TMEM63C,JPH3" GO: Molecular Function GO:0005244 voltage-gated ion channel activity 2.74E-12 7.29E-09 6.08E-10 5.15E-09 78 198 "KCNH8,ASIC2,KCNT1,KCNAB2,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KCNAB3,CACNA2D2,CLCN3,CLCN4,CNGA3,CYBB,CACNG7,CACNG3,CACNG2,HVCN1,GRIK1,GRIN1,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,HCN1,KCNK10,NALCN,KCNIP3,KCNIP2,KCNIP1,RYR1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SNAP25,SCN3B,ABCC8,TPCN2,KCNE5,KCNK12,KCNT2,KCNAB1" GO: Molecular Function GO:0022832 voltage-gated channel activity 2.74E-12 7.29E-09 6.08E-10 5.15E-09 78 198 "KCNH8,ASIC2,KCNT1,KCNAB2,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KCNAB3,CACNA2D2,CLCN3,CLCN4,CNGA3,CYBB,CACNG7,CACNG3,CACNG2,HVCN1,GRIK1,GRIN1,GRIN2D,GRM7,IL1RAPL1,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,HCN1,KCNK10,NALCN,KCNIP3,KCNIP2,KCNIP1,RYR1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SNAP25,SCN3B,ABCC8,TPCN2,KCNE5,KCNK12,KCNT2,KCNAB1" GO: Molecular Function GO:0005085 guanyl-nucleotide exchange factor activity 1.42E-11 3.79E-08 2.92E-09 2.47E-08 105 306 "ABR,ACTN2,PLEKHG5,BCAR3,AMPH,FGD2,ALS2,MADD,SPTBN4,DOCK11,FGF17,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,ARHGEF1,ARHGEF2,RCBTB2,CHRM4,NGEF,ARHGEF6,NRG2,CSF2RA,ARHGEF10,RASGEF1C,ARHGEF4,DOCK4,GAPVD1,ELMO1,TIAM2,DLG4,DOCK2,RASGRP1,EGFR,RASGRP2,ERBB2,ERBB4,DENND4A,FGF1,FGFR1,FGFR3,PSD2,FYN,DENND2A,RAPGEF6,GFRA1,GFRA2,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,DOCK7,KNDC1,JAK1,JAK2,KIT,SHC3,KITLG,NCAM1,PDGFRA,RASGEF1B,PSD,PTK2,RAB3IL1,RALGDS,IQSEC3,RASGRF1,RASGRF2,RET,ARHGEF10L,RIC8B,SBF1,FNIP1,ITSN1,DOCK10,PREX2,RAB3GAP1,ARHGEF40,FNBP1,SPTAN1,SPTB,IQSEC2,MCF2L2,ST5,RGL1,FGD4,ARHGEF9,MCF2L,DNMBP,DOCK9,PSD3,ARHGEF12,TEK,TIAM1,TRIO,VAV1,VAV2,P2RY12,DOCK8,SPATA13" GO: Molecular Function GO:0098772 molecular function regulator 4.87E-11 1.30E-07 9.26E-09 7.84E-08 357 1430 "RALGAPA1,SERPINA3,ABR,ACTN2,PLEKHG5,ELFN2,AXIN2,ADRB2,KIDINS220,AGT,TBC1D14,TAOK1,BCAR3,ARHGAP20,AMPH,OGT,DPP10,FGD2,PI16,CNIH2,APAF1,KCNAB2,APC,DGKZ,ALS2,APOC1,APOC2,LRRC4C,APP,PPP4R4,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,CCAR2,DYNLL1,ATP1B3,MTMR9,DOCK11,ADGRB3,RGS11,RGS9,FGF17,CFLAR,CDK5R1,ARHGEF7,C5,CDK5R2,CACNB2,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,CAST,BRSK2,ARHGEF25,CCKBR,KRIT1,CCNH,CCNT1,RGN,ARHGEF1,DGKI,ARHGEF2,KCNAB3,ARHGAP33,EVI5L,RCBTB2,SOCS6,CHM,CHN1,CHN2,CHRM4,ARHGAP22,SLIT2,NRXN3,PLAA,NRXN1,NRXN2,STOML1,NGEF,ARHGEF6,CABP1,BAG4,NRG2,NCOR1,RGS6,CSF2RA,ARHGEF10,SIPA1L1,SOCS5,PHACTR3,CST3,RASGEF1C,PPP1R16B,ARHGEF4,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ZEB2,ELMO1,B3GAT3,CNIH3,TIAM2,LYPD1,SPOCK3,SRGAP3,SGSM2,RABGAP1L,DLG4,DMPK,CPEB2,DOCK2,CASP8AP2,DPP6,ABI1,RCAN1,DNAJB6,ABCC9,SGK2,RASGRP1,FRY,CACNG7,FAM13A,EGFR,RASA4,TNK2,RGS17,PCOLCE2,RCAN2,RASGRP2,KCNMB2,ERBB2,ERBB4,DENND4A,CACNG3,CACNG2,TBC1D16,TAOK3,DLC1,RACK1,STRADA,PPP1R1B,FGF1,FGF12,FGF13,FGFR1,FGFR3,PRKAG2,HPCAL4,VTI1B,AGAP2,AGAP3,PSD2,ARFGAP2,ATP6V1H,NRG3,FYN,CAB39,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,MALT1,RUNDC3A,DBF4,PCSK1N,KCNMB4,ADAP1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,GRM2,GRM3,GRM7,ARHGAP19,NCKAP1L,ARHGAP36,HMGB1,AGFG1,HSP90AA1,SMAP1,IGF1,DOCK7,KNDC1,INPP5B,LRRTM3,LRRTM1,ITIH2,JAK1,JAK2,KCNK2,KIT,IPO5,STXBP5,LRRC4B,CAMK2N2,ARHGAP12,SHC3,MIA2,KITLG,MMP16,MMP17,GIT1,COL28A1,DBNL,MT3,MYO9A,NCAM1,NF1,NODAL,NOS1,NPY,TBC1D25,OCRL,OPHN1,PDGFRA,PDPK1,SERPINE2,SERPINI1,PIK3R1,A2ML1,GPSM2,FXYD1,PLXNB1,MED1,PPP1R1A,PPP2R2B,PPP2R2C,PTPA,PPP2R5C,PPP2R5E,RASGEF1B,PKIA,PRKAR1B,PRKCB,PRKCZ,MAPK8,MAPK9,PRPSAP2,PSD,BCAS3,PTK2,PTN,RAB3A,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,RNH1,FBXW7,SGSM1,LRRK2,KCNIP3,RTKN,KCNIP2,KCNIP1,SBF1,SCN2B,SCN4B,LRRTM4,FNIP1,ELMOD1,SEC14L1,RASA3,SGK1,SCG5,ITSN1,ASAP3,DOCK10,PREX2,RAB3GAP1,ARHGEF40,ARFGAP1,SLN,RIMS1,SNCB,SNCA,SCN3B,WDTC1,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,LRRC4,SSPO,ST5,RGL1,STX1A,FGD4,ARHGEF9,PLCB1,MCF2L,DNMBP,AZIN2,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,TIAM1,TIMP4,CABIN1,PIK3R5,TRIO,KCNE5,TSC1,TSC2,HSPBP1,SGK3,FLRT2,FLRT1,BCL2L13,VAV1,VAV2,TBC1D15,P2RY12,WNT7A,RICTOR,ELFN1,CRB2,WNK1,EVI5,KCNAB1,WNK3,GOPC,DOCK8,SOCS4,SPATA13" GO: Molecular Function GO:0005088 Ras guanyl-nucleotide exchange factor activity 7.27E-11 1.94E-07 1.29E-08 1.09E-07 84 232 "ABR,ACTN2,PLEKHG5,FGD2,ALS2,MADD,SPTBN4,DOCK11,FGF17,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,ARHGEF1,ARHGEF2,RCBTB2,NGEF,ARHGEF6,NRG2,CSF2RA,ARHGEF10,ARHGEF4,TIAM2,DLG4,DOCK2,RASGRP1,EGFR,ERBB2,ERBB4,DENND4A,FGF1,FGFR1,FGFR3,FYN,DENND2A,GFRA1,GFRA2,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,KNDC1,JAK1,JAK2,KIT,SHC3,KITLG,NCAM1,PDGFRA,RASGEF1B,PTK2,RAB3IL1,RASGRF1,RASGRF2,RET,ARHGEF10L,SBF1,ITSN1,DOCK10,PREX2,RAB3GAP1,ARHGEF40,SPTAN1,SPTB,MCF2L2,ST5,RGL1,FGD4,ARHGEF9,MCF2L,DNMBP,DOCK9,ARHGEF12,TEK,TIAM1,TRIO,VAV1,VAV2,SPATA13" GO: Molecular Function GO:0005509 calcium ion binding 9.90E-11 2.64E-07 1.65E-08 1.40E-07 198 708 "TTYH1,ACTN1,ACTN2,SLC25A25,ESYT2,SLC24A4,PCDH19,SPARCL1,PCDH10,LTBP4,SYT13,DOC2A,PITPNM2,ANXA7,CADPS,ASPH,PCDHGB4,ATP2A2,ATP2B2,CDK5R1,DST,CACNA1B,CACNA1E,CALB1,CALB2,CABP7,CALM1,CANX,CAPN3,SYT6,RGN,REPS2,CDH2,CDH8,CDH10,CDH18,CLGN,SLIT2,EPS15L1,CPNE6,NRXN1,SLC24A2,MYL6B,CABP1,CPS1,PLCH2,VCAN,NCAN,PITPNM3,DGKB,DGKG,SPOCK2,AIF1L,SPOCK3,CALN1,EDIL3,SYT15,RASGRP1,CELSR3,EML1,RASGRP2,NCALD,CDHR1,ADGRV1,EFEMP1,MEX3B,HPCAL4,SYT3,EFCAB2,CAMKK2,ATP2C1,CGREF1,DLL3,CAB39,SYT17,DNER,PCDH17,HPGDS,PCDH11X,GPD2,PCLO,PLCD4,ADAMTS13,GRIN1,GRM7,GSN,PADI2,MAN1B1,HPCA,NKD1,SCIN,C2CD4C,CDH20,SYTL4,MATN2,MATN3,SYT9,EFHB,LRP1B,MMP16,MMP17,MYL3,MYO5A,NELL1,NELL2,VWA2,NUCB1,NUCB2,PCDHGC3,PCDH8,PCDH9,ENPP2,PLCB2,PLCD1,SLC25A23,PCDH18,NECAB2,FAT3,PPP3CA,PPP3CB,EPDR1,DCHS2,MASP1,SYTL2,FAT4,CRTAC1,RET,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,S100B,ITSN1,CLSTN1,RPH3A,SLC8A1,EFHD1,SLIT1,SNCB,SNCA,SPTAN1,CLSTN2,SMOC1,SULF2,NECAB1,SYT11,RHBDL3,PLCB1,SYT1,SYT4,SYT5,ADGRL3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PHF24,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,VWCE,DNAH7,CRB1,THBS4,CDH22,TLL2,TPD52,TPM4,VLDLR,VSNL1,PCDH20,MICU3,CRB2,FSTL5,LRP8,PCDH15,PLSCR4" GO: Molecular Function GO:0015079 potassium ion transmembrane transporter activity 1.18E-10 3.15E-07 1.85E-08 1.57E-07 60 146 "KCNH8,SLC12A5,SLC24A4,KCNT1,KCNAB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,HCN2,KCNAB3,SLC24A2,CNGA3,SLC12A6,ABCC9,KCNMB2,TMEM175,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,HCN1,KCNK10,TMEM38A,KCNIP3,KCNIP2,KCNIP1,SLC12A4,SNAP25,ABCC8,KCNE5,KCNK12,KCNT2,KCNAB1" GO: Molecular Function GO:0008066 glutamate receptor activity 4.11E-10 1.09E-06 6.08E-08 5.15E-07 20 27 "GRIN3A,PTK2B,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" GO: Molecular Function GO:0022890 inorganic cation transmembrane transporter activity 6.03E-10 1.61E-06 8.46E-08 7.16E-07 157 542 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,SLC44A5,KCNT1,KCNAB2,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KCNAB3,CACNA2D2,ASIC3,SLC24A2,CNGA3,SLC4A7,COX4I1,SLC32A1,GRIN3A,SLC12A6,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,SLC9B2,ATP5PD,ATP13A4,TMEM175,ATP6V1H,ATP2C1,KCNMB4,GPM6A,GRIN1,CACFD1,GRM7,IL1RAPL1,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,SLC11A2,HCN1,KCNK10,PDE2A,SLC10A4,NALCN,PKD1,TMEM38A,CNNM2,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SNAP25,SCN3B,ABCC8,TPCN2,AZIN2,TF,SLC44A1,TRPC1,TRPC3,TRPM2,KCNE5,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,SLC39A12,JPH3" GO: Molecular Function GO:0044325 ion channel binding 7.24E-10 1.93E-06 9.64E-08 8.16E-07 53 127 "ACTN1,ACTN2,ANK2,ANK3,KCNAB2,ARRB1,ASPH,CALM1,HAP1,CAMK2D,CBARP,AKAP6,RIMS4,RIMS2,TCAF1,RIMS3,ABCC9,FGF12,FGF13,FHL1,NPTN,FYN,HSP90AA1,KCNB1,KCNC1,KCNC2,KCND3,KCNH1,KCNJ11,KCNQ3,NOS1,PDE4B,PDE4D,PIRT,PKD1,FXYD1,EPN1,LRRK2,KCNIP3,KCNIP2,KCNIP1,SCN4B,PPP1R9A,SLC8A1,RIMS1,SNAP25,SCN3B,STX1A,ABCC8,TRPC1,KCNE5,KCNAB1,GOPC" GO: Molecular Function GO:0019904 protein domain specific binding 8.21E-10 2.19E-06 1.04E-07 8.81E-07 199 729 "ACTN1,ACTN2,AXIN2,KIDINS220,CASKIN1,NR0B1,MRTFA,OGT,CNTNAP1,EPB41L5,APP,SHROOM2,CASK,ARHGAP5,RGS20,ARRB2,DYNLL1,ATP1A1,ATP2B1,ATP2B2,ATP2B3,RIPK1,ADAM15,BCL2L2,HCN2,SYNJ1,SYNJ2,CACNA1D,CACNB2,CALM1,HAP1,LDB2,SYNGR3,DLGAP2,DLGAP1,ASIC3,DLGAP3,CLCN3,TJP2,QKI,NIPBL,HOMER3,PICK1,AKAP7,WHRN,AKAP5,TCEAL2,ZNF521,NCOR1,RGS6,IPCEF1,ERC2,ARHGEF4,CTNND1,RIMS2,DOCK4,IST1,DAPK3,SIRPA,DNAJC6,ELMO1,DLG2,DLG3,DLG4,MED12,DNM2,SHANK1,ATN1,PDCD6IP,DTNA,EBF1,HEYL,ABI2,PLEKHA1,TNK2,OLIG2,EPB41L2,EFS,DLC1,RACK1,BAIAP2,HPCAL4,EVL,SGIP1,TACC2,STAMBP,TRIM16,KHDRBS3,MPP6,IGSF5,ARFIP1,GHR,KIRREL3,GNAS,LNX1,RAPGEF1,GRIA1,GRIA2,GRIK2,GRIK5,GRIN2C,GRM7,CIT,GSN,HNRNPK,TCEAL6,HSP90AA1,ATCAY,ICA1,NKD1,JAK2,KCNH2,KCNJ4,KCNJ9,KCNN2,L1CAM,LAMP2,MAPT,MEF2C,SRSF12,AFDN,MPP2,DBNL,MYO7A,TCEAL5,HNRNPM,NCAM1,NFE2L2,PAK3,PAX6,PDE2A,PIK3R1,PKD1,PLXNB3,STRN3,PRRX1,SH3KBP1,POU3F2,PPARA,MED1,PRKCZ,PROX1,CNTLN,PTK2,USP47,KHDRBS2,RDX,ROBO1,RXRA,STX1B,ATXN2,SCN2A,SCAF8,SH3BGR,SH3BP2,PPP1R9A,SHC4,NLGN1,SHANK2,ELMO2,SLC22A4,CXXC4,RIMS1,SNAP25,SNCA,SON,ENKUR,ERC1,NFASC,SSTR2,CEP68,STX1A,STXBP1,SYP,TACC1,TAF9,TBL1X,TCF7L2,TCF12,DICER1,SIRT1,TGFBR3,ZNF106,THRA,TJP1,CABIN1,TP53BP2,ZNF384,CADM1,MICAL1,LAT2,XPO1,TCEAL7,ZBTB16,PMEPA1,ZXDA,TUBA1A,PLSCR4,FZD3" GO: Molecular Function GO:0005267 potassium channel activity 1.40E-09 3.74E-06 1.70E-07 1.44E-06 51 122 "KCNH8,KCNT1,KCNAB2,HCN2,KCNAB3,CNGA3,ABCC9,KCNMB2,TMEM175,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,HCN1,KCNK10,TMEM38A,KCNIP3,KCNIP2,KCNIP1,SNAP25,ABCC8,KCNE5,KCNK12,KCNT2,KCNAB1" GO: Molecular Function GO:0015075 ion transmembrane transporter activity 2.16E-09 5.75E-06 2.50E-07 2.12E-06 229 873 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,SLC44A5,KCNT1,KCNAB2,SHROOM2,AQP6,SLC7A14,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,SLC16A4,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,SLC24A2,CNGA3,SLC4A7,SLC4A8,COX4I1,SLC32A1,CYBB,DLG3,DLG4,GRIN3A,SLC12A6,ABCC5,ABCC9,CACNG7,MFSD10,KCNMB2,SLC43A2,NCALD,CACNG3,CACNG2,PTK2B,ATP8A1,SLC9B2,ATP5PD,PCYOX1,ATP13A4,SLC37A3,TMEM175,HVCN1,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,GRM7,IL1RAPL1,SLC2A6,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,SFXN5,FXYD7,FXYD6,SLCO1C1,SLC11A2,HCN1,P2RX7,KCNK10,PDE2A,SLC10A4,BEST3,NALCN,PKD1,TMEM38A,FXYD1,SLC36A4,SLC26A11,CNNM2,SLC22A23,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SNAP25,SCN3B,MLC1,ABCC8,SLC37A2,ANO4,TPCN2,AZIN2,ATP13A2,TF,SLC44A1,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,SLC35A4,BEST1,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,SLC17A6,TMEM63C,SLC39A12,SLC4A10,JPH3" GO: Molecular Function GO:0030695 GTPase regulator activity 3.02E-09 8.06E-06 3.36E-07 2.84E-06 100 312 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ALS2,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ADGRB3,RGS11,RGS9,KALRN,KRIT1,ARHGEF1,DGKI,ARHGAP33,EVI5L,CHM,CHN1,CHN2,ARHGAP22,SLIT2,ARHGEF6,RGS6,SIPA1L1,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SRGAP3,SGSM2,RABGAP1L,CPEB2,DOCK2,FAM13A,RASA4,TNK2,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,ARFGAP2,IQGAP2,RUNDC3A,ADAP1,ARHGAP19,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,IPO5,STXBP5,ARHGAP12,GIT1,MYO9A,NF1,TBC1D25,OCRL,OPHN1,GPSM2,PLXNB1,RALGDS,RAP1GAP,RAP1GDS1,RGS3,RGS4,RGS7,RGS10,RGS12,RIC8B,SGSM1,LRRK2,RTKN,ELMOD1,RASA3,ASAP3,PREX2,RAB3GAP1,ARFGAP1,RIMS1,ARHGAP26,RAP1GAP2,PLCB1,ARHGEF12,ARHGAP9,TSC1,TSC2,TBC1D15,EVI5,GOPC" GO: Molecular Function GO:0003779 actin binding 3.25E-09 8.67E-06 3.47E-07 2.93E-06 124 412 "ACTN1,ACTN2,FMNL2,ADD1,ADD2,ADD3,ERMN,MRTFA,BIN1,MYH7B,GAS7,SHTN1,SHROOM2,SPTBN4,DST,WASF1,CACNB2,CAMK2B,HIP1R,FMNL3,CFL2,CNN3,PICK1,AKAP5,MYRIP,MICAL2,SIPA1L1,PHACTR3,AIF1L,DBN1,KLHL3,BLOC1S6,FBXO25,DMD,USH1C,KLHL5,EGFR,EPB41,EPB41L1,EPB41L2,DMTN,MTSS1L,EPS8,NCALD,RCSD1,CORO2B,FER,CAP2,EVL,FLNC,SORBS1,PDLIM5,ABLIM2,IQGAP2,WASF3,MYOZ2,GSN,SYNPO,HPCA,SCIN,KCNMA1,PACRG,DBNL,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,OPHN1,SNTG1,TMOD2,SSH1,ANLN,PLEC,PTK2,PXK,RDX,MYH14,LRRK2,PPP1R9A,MYO18A,FHOD3,ABLIM3,SMTN,PKNOX2,CCDC88A,MYH15,LIMCH1,PALLD,MYO16,SPTAN1,SPTB,CLASP2,ITPRID2,EPB41L3,MPRIP,FGD4,SYNE2,SYN1,ARC,COBL,KLHL4,SYNE1,TMOD1,DAAM2,TNS1,TPM1,TPM2,TPM3,TPM4,SYNPO2,RUSC1,PLEKHH2,MICAL1,WIPF1,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Molecular Function GO:0022857 transmembrane transporter activity 1.13E-08 3.01E-05 1.16E-06 9.79E-06 256 1014 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,SLC44A5,ABCD2,KCNT1,KCNAB2,SHROOM2,AQP4,AQP6,SLC7A14,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ATP6V1G2,ATP6V0A1,AZGP1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,SLC5A11,SLC16A4,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,SLC24A2,ABCG2,CNGA3,SLC4A7,SLC4A8,COX4I1,SLC32A1,ABCG1,SLC45A1,CYBB,TOMM20,SV2B,SV2A,DLG3,DLG4,GRIN3A,SLC29A4,SLC12A6,SLC25A18,ABCC5,ABCC9,SIDT2,CACNG7,MFSD10,KCNMB2,SLC43A2,NCALD,ABCA8,CACNG3,CACNG2,PTK2B,ATP8A1,TOMM40L,SLC9B2,ATP5PD,PCYOX1,ATP13A4,SLC37A3,TMEM175,HVCN1,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GJB1,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,GRM7,IL1RAPL1,MFSD2A,SLC2A6,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,SFXN5,AQP11,FXYD7,FXYD6,SLCO1C1,SLC11A2,HCN1,P2RX7,KCNK10,PDE2A,SLC10A4,BEST3,ABCB1,NALCN,PKD1,TMEM38A,FXYD1,SLC36A4,SLC26A11,CNNM2,SLC22A23,SIDT1,SLC6A15,SLC25A36,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SNAP25,SCN3B,MLC1,ABCC8,SLC37A2,ANO4,TPCN2,AZIN2,SLC19A3,ATP13A2,TF,SLC44A1,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,SLC35A4,BEST1,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,SLC17A6,HNRNPA3,TMEM63C,GJC2,SLC39A12,SLC4A10,JPH3" GO: Molecular Function GO:0015077 monovalent inorganic cation transmembrane transporter activity 1.49E-08 3.98E-05 1.47E-06 1.25E-05 113 375 "KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,SLC44A5,KCNT1,KCNAB2,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP6V1G2,ATP6V0A1,HCN2,KCNAB3,ASIC3,SLC24A2,CNGA3,SLC4A7,COX4I1,SLC32A1,SLC12A6,ABCC9,KCNMB2,SLC9B2,ATP5PD,TMEM175,ATP6V1H,KCNMB4,SLC6A17,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,SLC11A2,HCN1,KCNK10,SLC10A4,NALCN,TMEM38A,SLC6A15,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SNAP25,SCN3B,ABCC8,AZIN2,SLC44A1,TRPM2,KCNE5,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC38A1,SLC17A7,KCNAB1" GO: Molecular Function GO:0022834 ligand-gated channel activity 1.73E-08 4.60E-05 1.59E-06 1.34E-05 56 148 "ASIC2,ASIC1,SHROOM2,HCN2,CALM1,P2RX6,ASIC3,CHRNA4,CHRNB2,CNGA3,DLG3,DLG4,GRIN3A,NCALD,PTK2B,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,HCN1,P2RX7,RYR1,RYR3,SCNN1D,RASA3,ABCC8,TPCN2,SLC17A7,JPH3" GO: Molecular Function GO:0015276 ligand-gated ion channel activity 1.73E-08 4.60E-05 1.59E-06 1.34E-05 56 148 "ASIC2,ASIC1,SHROOM2,HCN2,CALM1,P2RX6,ASIC3,CHRNA4,CHRNB2,CNGA3,DLG3,DLG4,GRIN3A,NCALD,PTK2B,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,HCN1,P2RX7,RYR1,RYR3,SCNN1D,RASA3,ABCC8,TPCN2,SLC17A7,JPH3" GO: Molecular Function GO:0019894 kinesin binding 2.18E-08 5.80E-05 1.91E-06 1.62E-05 24 42 "SHTN1,SPAG9,PRC1,ARHGEF10,STAU2,NEK6,DISC1,KIF3A,ATCAY,KCNA2,KCNC1,KTN1,NEFH,JAKMIP1,MAPK8,AP1AR,SYBU,CLSTN1,SNCA,KIF1B,MAPK8IP3,KLC2,LRP8,IFT88" GO: Molecular Function GO:0030276 clathrin binding 2.29E-08 6.11E-05 1.91E-06 1.62E-05 32 66 "AP2A1,AP2A2,SYT13,DOC2A,ARRB1,SYT6,HIP1R,CLTA,CLTB,CLTC,CALY,SNAP91,TOM1,SYT15,NCALD,SYT3,NSG2,NSG1,SYT17,DNER,SMAP1,C2CD4C,SYTL4,SYT9,SYTL2,LRRK2,RPH3A,SYT11,SYT1,SYT4,SYT5,TOM1L2" GO: Molecular Function GO:0060589 nucleoside-triphosphatase regulator activity 2.30E-08 6.13E-05 1.91E-06 1.62E-05 105 344 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ALS2,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,ADGRB3,RGS11,RGS9,KALRN,BRSK2,KRIT1,ARHGEF1,DGKI,ARHGAP33,EVI5L,CHM,CHN1,CHN2,ARHGAP22,SLIT2,ARHGEF6,BAG4,RGS6,SIPA1L1,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SRGAP3,SGSM2,RABGAP1L,CPEB2,DOCK2,DNAJB6,FAM13A,RASA4,TNK2,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,ARFGAP2,IQGAP2,RUNDC3A,ADAP1,ARHGAP19,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,IPO5,STXBP5,ARHGAP12,GIT1,MYO9A,NF1,TBC1D25,OCRL,OPHN1,GPSM2,PLXNB1,RAB3A,RALGDS,RAP1GAP,RAP1GDS1,RGS3,RGS4,RGS7,RGS10,RGS12,RIC8B,SGSM1,LRRK2,RTKN,ELMOD1,RASA3,ASAP3,PREX2,RAB3GAP1,ARFGAP1,RIMS1,ARHGAP26,RAP1GAP2,PLCB1,ARHGEF12,ARHGAP9,TSC1,TSC2,TBC1D15,EVI5,GOPC" GO: Molecular Function GO:0005215 transporter activity 4.22E-08 1.13E-04 3.41E-06 2.89E-05 312 1294 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,AP2A1,SLC44A5,AP2A2,AP1B1,OSBPL8,ABCD2,KCNT1,KCNAB2,SHROOM2,AQP4,AQP6,SLC7A14,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ATP6V1G2,ATP6V0A1,AZGP1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,SLC5A11,SLC16A4,P2RX6,SCARB1,AP4M1,KCNAB3,CACNA2D2,ASIC3,SYNPR,CHRNA4,CHRNB2,SLC22A6,CPNE6,CLCN3,CLCN4,SLC24A2,ABCG2,TMEM184B,CNGA3,SLC4A7,SLC4A8,COX4I1,SLC32A1,ABCG1,IPCEF1,PITPNM3,SLC45A1,SEC14L5,CYBB,ZFYVE16,TOMM20,PITPNC1,SV2B,SV2A,DLG3,DLG4,GRIN3A,SLC29A4,SLC12A6,SLC25A18,ABCC5,ABCC9,SIDT2,CACNG7,CALCRL,MFSD10,KCNMB2,SLC43A2,NCALD,VPS26C,CD320,CLVS1,ABCA8,FABP7,CACNG3,CACNG2,PTK2B,ATP8A1,TOMM40L,SEC24B,SLC9B2,ATP5PD,PCYOX1,ATP13A4,SLC37A3,FOLR2,TMEM175,HVCN1,ATP6V1H,ATP2C1,PRELID3A,AP4B1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,ATP8A2,CPLX1,GJB1,GLRB,KCNMB4,GPM6A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,GRM7,IL1RAPL1,MFSD2A,AP4S1,SLC2A6,HBA1,PACSIN2,TNFAIP8L3,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,CLVS2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,KPNA5,IPO5,TTYH2,SFXN5,AQP11,MTTP,FXYD7,FXYD6,SLCO1C1,SLC11A2,HCN1,P2RX7,KCNK10,PDE2A,SLC10A4,BEST3,ABCB1,NALCN,PKD1,TMEM38A,FXYD1,PMP2,SLC36A4,TNPO2,SLC26A11,CNNM2,SLC22A23,SIDT1,SLC6A15,RLBP1,SLC25A36,ATP8B4,ABCA11P,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,SCP2,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SNAP25,LMBRD1,SCN3B,ATP10B,APOM,MLC1,ABCC8,SYN1,SYP,SYPL1,SLC37A2,ATP11A,ANO4,TPCN2,AZIN2,SLC19A3,ATP13A2,TF,SLC44A1,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,TTPA,EIF4ENIF1,SLC35A4,PITPNB,VLDLR,BEST1,SLC13A3,KCNK12,XPO1,SLC47A2,KCNT2,ATP6V0E2,SLC26A10,UPF3A,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,SLC17A6,PLSCR4,HNRNPA3,TMEM63C,GJC2,NUP214,SLC39A12,AP3B2,SLC4A10,JPH3" GO: Molecular Function GO:0008324 cation transmembrane transporter activity 4.88E-08 1.30E-04 3.82E-06 3.24E-05 172 642 "TTYH1,KCNH8,ASIC2,ASIC1,SLC12A5,SLC24A4,SLC44A5,KCNT1,KCNAB2,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,P2RX6,KCNAB3,CACNA2D2,ASIC3,CHRNA4,CHRNB2,SLC24A2,CNGA3,SLC4A7,COX4I1,SLC32A1,GRIN3A,SLC12A6,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,ATP8A1,SLC9B2,ATP5PD,ATP13A4,TMEM175,HVCN1,ATP6V1H,ATP2C1,KCNMB4,GPM6A,GRIK1,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,SLC2A6,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,SLC11A2,HCN1,P2RX7,KCNK10,PDE2A,SLC10A4,NALCN,PKD1,TMEM38A,SLC36A4,CNNM2,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLC22A4,SNAP25,SCN3B,ABCC8,TPCN2,AZIN2,ATP13A2,TF,SLC44A1,TRPC1,TRPC3,TRPM2,KCNE5,SLC35A4,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,TMEM63C,SLC39A12,JPH3" GO: Molecular Function GO:0005249 voltage-gated potassium channel activity 5.19E-08 1.38E-04 3.95E-06 3.35E-05 39 91 "KCNH8,KCNT1,KCNAB2,HCN2,KCNAB3,CNGA3,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,HCN1,KCNIP2,SNAP25,ABCC8,KCNE5,KCNT2,KCNAB1" GO: Molecular Function GO:0015631 tubulin binding 8.05E-08 2.14E-04 5.96E-06 5.04E-05 91 293 "KIF6,APC,MARK4,KIF1A,DST,PRC1,KRIT1,ARHGEF2,CNN3,CLIP3,FEZ1,KATNAL2,KIF26A,JAKMIP2,KIF19,DYNC1I1,DNM2,DPYSL2,EML1,NCALD,APC2,KATNAL1,FGF13,CAMSAP1,SGIP1,TPPP3,BRSK1,FYN,TUBGCP4,PPARGC1A,GNAS,PSRC1,STMN2,TPPP,KIF3A,GABARAPL2,AGBL5,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,STMN1,PACRG,MAP2,MAP4,MAP6,MAPT,MID1,JAKMIP3,BLOC1S2,NEFM,NEFH,NF1,NUMA1,OGG1,PDE4B,CCSER2,JAKMIP1,PPP5C,BCAS3,RAD51D,TTLL7,KIF7,MAP6D1,LRRK2,CLIP1,KIF27,KIF21A,KIF16B,SYBU,SIRT2,CCDC88A,CDK5RAP2,SNCB,SNCA,KIF13A,KIF21B,KIF1B,CLASP2,MTCL1,CAMSAP2,AGTPBP1,CLASP1,TIAM1,NEIL2,CLIP2,FMN2,REEP1,DPYSL5,STMN4" GO: Molecular Function GO:0005089 Rho guanyl-nucleotide exchange factor activity 1.34E-07 3.56E-04 9.62E-06 8.15E-05 35 80 "ABR,PLEKHG5,FGD2,ALS2,DOCK11,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,DOCK2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,DOCK10,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,DOCK9,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" GO: Molecular Function GO:0016301 kinase activity 2.02E-07 5.37E-04 1.41E-05 1.20E-04 215 853 "KCNH8,CLK4,CDC7,NME5,AK2,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,CDK13,STK33,MARK4,ATM,RIPK1,FGF17,NRP2,KSR1,BMPR1B,CDK5R1,BTK,MMD2,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CCNH,CCNT1,CD86,DGKI,CDK11B,DCLK1,TBRG4,TAOK2,TJP2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,FGFR1OP2,RASSF2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,AK5,DLG2,DLG3,DLG4,DMPK,RPS6KL1,GNE,DYRK1A,EDNRA,SGK2,HIPK3,EFNA3,EFNB3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,EFEMP1,STRADA,TESK2,FER,FGF1,FGFR1,FGFR3,FGR,PRKAG2,IP6K2,FLT1,AK8,TPK1,NPTN,CAMKK2,MPP6,BRSK1,FYN,GAB1,CAB39,NEK6,IP6K3,GCK,GK,TTBK1,DBF4,DCLK2,GRK4,CNTRL,CIT,MAP4K5,IRAK3,HSP90AA1,MYLK2,NIM1K,NME9,ITPKA,ITPKB,JAK1,JAK2,KCNH1,KCNH2,KHK,KIT,MARK1,MARK3,MATK,KITLG,MPP2,STK32C,NRBP2,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,PHKG1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKM,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,SNRK,PTK2,PXK,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,HKDC1,MAGI3,SEPHS1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TGFBR3,TIE1,TK2,PIK3R5,CDK20,TRIO,SGK3,VAV1,SPHK2,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" GO: Molecular Function GO:0004970 ionotropic glutamate receptor activity 2.17E-07 5.77E-04 1.48E-05 1.25E-04 14 19 "GRIN3A,PTK2B,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" GO: Molecular Function GO:0005543 phospholipid binding 2.55E-07 6.79E-04 1.70E-05 1.44E-04 111 385 "ACTN2,SNX30,ESYT2,SNX32,OSBPL1A,WDR35,OSBPL8,SYT13,DOC2A,PITPNM2,AMPH,OGT,FGD2,PHF12,ANXA7,APOC1,AMER3,SPTBN4,ZFYVE28,PLA2G4C,CADPS,BTK,SYT6,HIP1R,KRIT1,SCARB1,ARHGAP33,CPNE6,ZFYVE9,CPS1,ABCG1,ARHGAP32,FRMPD4,ZFYVE16,SNAP91,SNX29,SYT15,RASGRP1,PLEKHA1,EPB41,MTSS1L,F3,CLVS1,RPS6KC1,SH3YL1,ANKFY1,PSD2,SGIP1,SYT3,RAPGEF6,IQGAP2,GAP43,SYT17,ARFIP1,WASHC2A,FERMT2,GPR12,ADAP1,LPAR4,PCLO,PACSIN2,TNFAIP8L3,HMGB1,SCIN,C2CD4C,CLVS2,SYTL4,MARK1,SYT9,NF1,NRGN,HCN1,OPHN1,PIRT,PIK3C2A,SNX10,PLCB2,PLCD1,MAPKAP1,PACSIN1,PSD,SYTL2,PTAFR,PXK,RPE65,SNX22,AMER2,KIF16B,RPH3A,CCDC88A,SNCA,ARHGAP26,APOM,NSFL1C,SYT11,PLCB1,SYT1,SYT4,SYT5,MCF2L,ARHGAP9,ATP13A2,TIAM1,PARD3,TTPA,TUB,SGK3,PITPNB,SNX27,MPPE1,SNX14" GO: Molecular Function GO:0008017 microtubule binding 2.85E-07 7.60E-04 1.85E-05 1.57E-04 70 214 "KIF6,APC,MARK4,KIF1A,DST,PRC1,KRIT1,ARHGEF2,CNN3,CLIP3,KATNAL2,KIF26A,JAKMIP2,KIF19,DYNC1I1,DNM2,DPYSL2,EML1,APC2,KATNAL1,FGF13,CAMSAP1,SGIP1,TUBGCP4,PSRC1,TPPP,KIF3A,GABARAPL2,KIF2A,KIF5A,KIF5C,KIFC3,MAP2,MAP4,MAP6,MAPT,MID1,JAKMIP3,NEFM,NEFH,NF1,NUMA1,OGG1,CCSER2,JAKMIP1,PPP5C,KIF7,MAP6D1,LRRK2,CLIP1,KIF27,KIF21A,KIF16B,SYBU,CCDC88A,CDK5RAP2,SNCA,KIF13A,KIF21B,KIF1B,CLASP2,MTCL1,CAMSAP2,CLASP1,TIAM1,NEIL2,CLIP2,FMN2,REEP1,DPYSL5" GO: Molecular Function GO:0016773 "phosphotransferase activity, alcohol group as acceptor" 3.99E-07 1.06E-03 2.53E-05 2.14E-04 198 781 "KCNH8,CLK4,CDC7,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,DGKZ,DGKD,CDK10,PDXK,CASK,CDK13,STK33,MARK4,ATM,RIPK1,FGF17,NRP2,KSR1,BMPR1B,CDK5R1,BTK,MMD2,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CCNH,CCNT1,CD86,DGKI,CDK11B,DCLK1,TBRG4,TAOK2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,FGFR1OP2,RASSF2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DMPK,RPS6KL1,GNE,DYRK1A,EDNRA,SGK2,HIPK3,EFNA3,EFNB3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,EFEMP1,STRADA,TESK2,FER,FGF1,FGFR1,FGFR3,FGR,PRKAG2,IP6K2,FLT1,NPTN,CAMKK2,BRSK1,FYN,GAB1,CAB39,NEK6,IP6K3,GCK,GK,TTBK1,DBF4,DCLK2,GRK4,CNTRL,CIT,MAP4K5,IRAK3,HSP90AA1,MYLK2,NIM1K,ITPKA,ITPKB,JAK1,JAK2,KCNH1,KCNH2,KHK,KIT,MARK1,MARK3,MATK,KITLG,STK32C,NRBP2,IDNK,NEK1,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,PHKG1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKM,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,SNRK,PTK2,PXK,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,HKDC1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TGFBR3,TIE1,PIK3R5,CDK20,TRIO,SGK3,VAV1,SPHK2,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" GO: Molecular Function GO:0008022 protein C-terminus binding 4.16E-07 1.11E-03 2.57E-05 2.18E-04 72 224 "ADCY8,AP2A1,LRRC7,AMPH,DGKZ,CASK,DYNLL1,ATP2A2,ATP2B2,MPDZ,KSR1,DST,SYNJ1,BAIAP3,CACNA1B,MAGI1,FOXN3,PLEKHB1,CLTC,TJP2,NIPBL,CNGA3,HOMER3,PICK1,AKAP7,DAPK3,DLG2,DLG3,DLG4,DNM1,MED12,SHANK1,OPTN,ERBB2,ERCC2,BAIAP2,HPCAL4,SDCBP2,MCHR1,JAK2,KCNJ11,KCNK3,LIG4,AFDN,DBNL,BLOC1S2,NCF2,HCN1,OPRL1,SNTG1,PIK3R1,PXK,PEX5,RAB3A,RASGRF1,FIGN,KCNIP3,ATXN1,ATXN2,PPP1R9A,PEX26,SHANK2,PRRC2C,SYT1,TBL1X,TCF4,SIRT1,ITGB3BP,TJP1,XRCC4,ZBTB16,GOPC" GO: Molecular Function GO:0005096 GTPase activator activity 5.13E-07 1.37E-03 3.11E-05 2.63E-04 86 283 "RALGAPA1,ABR,AXIN2,TBC1D14,ARHGAP20,ALS2,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ADGRB3,RGS11,RGS9,KALRN,ARHGEF1,ARHGAP33,EVI5L,CHM,CHN1,CHN2,ARHGAP22,ARHGEF6,RGS6,SIPA1L1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,TIAM2,SRGAP3,SGSM2,RABGAP1L,DOCK2,FAM13A,RASA4,RGS17,TBC1D16,DLC1,AGAP2,AGAP3,ARFGAP2,IQGAP2,ADAP1,ARHGAP19,NCKAP1L,ARHGAP36,AGFG1,SMAP1,INPP5B,STXBP5,ARHGAP12,GIT1,MYO9A,NF1,TBC1D25,OCRL,OPHN1,PLXNB1,RAP1GAP,RAP1GDS1,RGS3,RGS4,RGS7,RGS10,RGS12,RIC8B,SGSM1,LRRK2,ELMOD1,RASA3,ASAP3,PREX2,RAB3GAP1,ARFGAP1,ARHGAP26,RAP1GAP2,PLCB1,ARHGEF12,ARHGAP9,TSC2,TBC1D15,EVI5" GO: Molecular Function GO:0005234 extracellularly glutamate-gated ion channel activity 6.00E-07 1.60E-03 3.55E-05 3.01E-04 14 20 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,SLC17A7" GO: Molecular Function GO:0030165 PDZ domain binding 8.35E-07 2.22E-03 4.83E-05 4.09E-04 43 114 "KIDINS220,CASK,ATP2B1,ATP2B2,ATP2B3,HCN2,SYNJ2,CACNA1D,ASIC3,DLGAP3,CLCN3,ERC2,DOCK4,DLG2,DLG3,DLG4,DTNA,PLEKHA1,BAIAP2,MPP6,IGSF5,KIRREL3,LNX1,GRIA1,GRIA2,GRIK2,GRIK5,GRIN2C,GRM7,CIT,NKD1,KCNJ4,KCNJ9,L1CAM,MPP2,NLGN1,SLC22A4,CXXC4,ERC1,SSTR2,TGFBR3,CADM1,FZD3" GO: Molecular Function GO:0004672 protein kinase activity 1.24E-06 3.30E-03 7.02E-05 5.94E-04 167 649 "KCNH8,CLK4,CDC7,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,ATM,RIPK1,FGF17,NRP2,KSR1,BMPR1B,CDK5R1,BTK,MMD2,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CCNH,CCNT1,CDK11B,DCLK1,TBRG4,TAOK2,MAP4K4,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,FGFR1OP2,RASSF2,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,EDNRA,SGK2,HIPK3,EFNA3,EFNB3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,EFEMP1,STRADA,TESK2,FER,FGF1,FGFR1,FGFR3,FGR,PRKAG2,FLT1,NPTN,CAMKK2,BRSK1,FYN,CAB39,NEK6,TTBK1,DBF4,DCLK2,GRK4,CNTRL,CIT,MAP4K5,IRAK3,HSP90AA1,MYLK2,NIM1K,ITPKA,JAK1,JAK2,KCNH1,KCNH2,KIT,MARK1,MARK3,MATK,STK32C,NRBP2,NEK1,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,CAMKV,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,SNRK,PTK2,PXK,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TGFBR3,TIE1,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" GO: Molecular Function GO:0030507 spectrin binding 1.76E-06 4.69E-03 9.78E-05 8.28E-04 18 32 "ADD1,ADD2,ANK1,ANK2,ANK3,SPTBN4,DYNC1I1,USH1C,EPB41,EPB41L2,DMTN,CAMSAP1,DCTN2,KIF3A,MYO7A,PTPRN,SPTAN1,CAMSAP2" GO: Molecular Function GO:0044877 protein-containing complex binding 2.71E-06 7.22E-03 1.47E-04 1.25E-03 368 1626 "ABCF1,ACHE,RBM10,ACTN1,ACTN2,ARID1A,ADCY2,ADD1,ADD2,ERMN,ADORA1,ADRB2,BEND6,MTA3,AP2A1,AP2A2,C1QTNF1,LTBP4,AMPH,KIF6,BIN1,SEMA7A,EP400,PHF12,PPFIA2,ANXA7,PARG,APBB1,APC,GAS7,SHTN1,SHROOM2,CASK,ARRB1,ARRB2,ASCL1,MARK4,NCOA1,CCAR2,ATM,RIPK1,KIF1A,ADAM23,ADAM15,RGS9,HCN2,CFLAR,DST,SYNJ1,WASF1,DDR1,CACNB2,PRC1,KRIT1,CCNT1,SCARB1,CD81,ARHGEF2,CDH2,DLGAP1,LRWD1,NOG,ADGRG1,LHX2,VAX2,NIPBL,CNN3,PICK1,LETMD1,AKAP5,ABI3BP,CPS1,CLOCK,HINFP,NCOR1,NCOR2,CLIP3,SIPA1L1,CHD5,CALY,ERC2,KATNAL2,HDAC4,KIF26A,TBC1D5,IST1,AIF1L,GIT2,DBN1,JAKMIP2,HP1BP3,MAGI2,BLOC1S6,SACS,KIF19,DLG4,DLX1,DNM1,USP3,MED12,DYNC1I1,DNM2,SHANK1,CPEB2,DOCK2,DPYSL2,DRD1,ABI1,ECM2,USH1C,EDIL3,EGFR,ABI2,PCOLCE2,EML1,COQ7,EPHB1,APC2,RCSD1,KATNAL1,EZH1,WAC,PTK2B,CORO2B,FCGR1A,FCGR1B,FCGR3A,FCGRT,PRMT5,FGF1,FGF13,FGFR1,FGR,CAMSAP1,FOXO3,FLNC,SGIP1,SORBS1,STAU2,FYB1,FYN,STAG2,GABRB3,ZMYND11,NCKAP1,IQGAP2,DISC1,ALDH1L1,TUBGCP4,GFAP,GFRA1,PPARGC1A,GLI2,TOX3,CBX1,GNAL,GNAO1,GNAS,PSRC1,GPER1,RAPGEF4,TPPP,GRB10,ADAMTS13,ADAMTS8,NR3C1,KIF3A,PSIP1,MUM1,NCKAP1L,GABARAPL2,HNRNPK,HSP90AA1,HTR2A,MSL1,IGF1,RBPJ,SCIN,HES5,INSM1,ITGA7,KCNMA1,KIF2A,KIF5A,KIF5C,KIFC3,KLRC2,L1CAM,LMO2,MAP2,MAP4,MAP6,MAPT,MBD1,ADAM11,MEF2C,MEIS1,MID1,MITF,GIT1,DBNL,JAKMIP3,ADAM22,MSR1,CTNNA3,MYH3,MYO6,MYO7A,NAP1L2,NASP,NEFM,NEFH,NEUROD1,NF1,NFIA,NKX2-2,NME4,HCN1,DDR2,NUMA1,OGG1,PAX6,PCSK2,PDGFRA,PDPK1,OLA1,PFKP,PIK3R1,CCSER2,PKM,PLCB2,JAKMIP1,MTRF1L,PRIMPOL,STRN3,PMS2,POLG,PPARA,MED1,PPP2R2B,LRRN3,PPP5C,PRKCB,BCAS3,APTX,PTCH1,PTK2,SPDL1,FEZF2,RFX4,KIF7,SEC61A2,PBRM1,RNASEL,MYH14,ELP2,MCMBP,MAP6D1,LRRK2,CLIP1,RXRA,AP1AR,SAFB,SALL1,SATB1,ATXN1,ATXN7,SFPQ,KIF27,KIF21A,PPP1R9A,ARX,KIF16B,CPEB3,MYO18A,SHMT2,SYBU,RPH3A,PEX26,DHX30,PKNOX2,KDM4D,SIRT2,CDK5RAP3,CCDC88A,CPEB4,ZKSCAN3,SMARCA4,SMARCC2,CDK5RAP2,SMARCD3,SMARCE1,SNCA,MBD5,KIF13A,LMBRD1,MYO16,SOX2,KIF21B,SOX10,DOK5,SOX15,KDM4C,SPTAN1,SPTB,KIF1B,CLASP2,CAMTA2,ITPRID2,ERBIN,FCHO1,MLC1,FGD4,SUPT5H,SYNE2,SYP,MTCL1,TAL1,CAMSAP2,TBL1X,SMG6,TCF4,SIN3B,SATB2,TCF7L2,ZEB1,CLASP1,SYNE1,NSD1,SIRT1,TGFBR3,THBS4,THRA,TIAM1,RELL2,CBX5,ICAM5,TMOD1,KCTD2,KAT6B,CABIN1,TNR,PIK3R5,WBP2,DOK6,NEIL2,TRPS1,ZMYND8,TSN,TUB,VLDLR,WIPF1,CLIP2,NSD2,WRN,RICTOR,ZIC2,FMN2,REEP1,DPYSL5,MEIS3,LRP8,PRDM8,PCDH15,WIPF2,NELFE,RTN4,KAT6A" GO: Molecular Function GO:0016247 channel regulator activity 3.78E-06 1.01E-02 2.02E-04 1.71E-03 48 139 "ADRB2,AGT,DPP10,CNIH2,KCNAB2,CACNB2,CAMK2D,KCNAB3,NRXN3,NRXN1,NRXN2,STOML1,CNIH3,DPP6,ABCC9,SGK2,CACNG7,KCNMB2,CACNG3,CACNG2,RACK1,FGF12,FGF13,HPCAL4,VTI1B,KCNMB4,GRM2,GRM3,GRM7,KCNK2,NOS1,NPY,FXYD1,PRKCB,PRKCZ,KCNIP3,KCNIP2,KCNIP1,SCN2B,SCN4B,SGK1,SCN3B,STX1A,KCNE5,SGK3,WNK1,KCNAB1,WNK3" GO: Molecular Function GO:0015081 sodium ion transmembrane transporter activity 4.64E-06 1.24E-02 2.42E-04 2.05E-03 47 136 "ASIC2,ASIC1,SLC24A4,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,HCN2,ASIC3,SLC24A2,SLC4A7,SLC32A1,SLC6A17,KCNK1,HCN1,SLC10A4,NALCN,SLC6A15,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC20A2,SCN3B,TRPM2,SLC13A3,SLC38A1,SLC17A7" GO: Molecular Function GO:0032559 adenyl ribonucleotide binding 5.24E-06 1.40E-02 2.69E-04 2.27E-03 344 1518 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,DGKD,CDK10,PDXK,CASK,CDK13,STK33,DNAH17,MARK4,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,CLCN4,ABCG2,MAP4K4,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,AK5,KIF19,DMPK,DNAH9,RPS6KL1,GNE,DYRK1A,FARSB,ABCC5,ABCC9,AASDH,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,NEK6,IP6K3,ATP8A2,ACSS1,GART,GCK,SRCAP,GK,TTBK1,GLUL,DCLK2,GRK4,RAPGEF4,CIT,KIF3A,BVES,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,NIM1K,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,HCN1,NTRK2,NTRK3,DDR2,KSR2,P2RX7,P2RY1,PAK3,PC,CDK18,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,PTPA,PPP5C,PRKACB,PRKAR1B,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RNASEL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,TTBK2,ACSBG1,ABCC8,SYN1,SYN2,POPDC3,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,TIE1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0019899 enzyme binding 6.03E-06 1.61E-02 3.03E-04 2.57E-03 426 1929 "ABAT,FMNL2,ELFN2,ADCY2,ADCY5,ADCY6,ADCYAP1R1,ADD3,AXIN2,SLC12A5,ADORA2A,ADRB2,KIDINS220,AP2A1,AP2A2,AP1B1,HACE1,TBC1D14,PLA2G6,TAOK1,SPOP,BIN1,ANK1,ANK2,FGD2,APBB1,APBB2,APC,ALS2,APOC2,USP37,APP,SPTBN4,ARHGDIA,ARRB1,RGS20,ARRB2,CADPS,DACT3,NCOA1,CCAR2,DYNLL1,ATP1A1,ATP1B3,ATP2A2,ATP6V0A1,RIPK1,DOCK11,BARD1,BCHE,BID,CFLAR,KSR1,CDK5R1,ARHGEF7,NAE1,WASF1,CACNA1B,CACNB2,CACNB4,DIRAS1,CALM1,KALRN,CAMK2B,CAMK2D,CAPN3,CAST,BRSK2,SPAG9,PRC1,CBS,LDB2,FMNL3,CCNT1,USP2,DGKI,ARHGEF2,CDC25B,CDC27,CDC42,CDH2,EVI5L,DIS3L,COPB2,CHM,TAOK2,CLU,CLTC,FBXO7,NIPBL,PICK1,AKAP7,AKAP6,AKAP5,BAG4,MYRIP,CDC42BPB,AKAP12,CRY2,RNF14,HINFP,NCOR1,NCOR2,SNCAIP,CSF1R,FEZ1,SIPA1L1,CHD5,VCAN,SOCS5,PDE4DIP,PHACTR3,CNTNAP2,CST3,DZIP3,PITPNM3,APPL1,CTNND1,RIMS2,PPP6R2,USP6NL,NOS1AP,DOCK4,HDAC9,HDAC4,TBC1D5,MAML1,DAPK3,DBT,JAKMIP2,RUSC2,MAGI2,SMG7,SNAP91,PARD6A,SV2A,SRGAP3,SGSM2,RABGAP1L,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM1,DNM2,SLC12A6,CASP8AP2,DPYSL2,DRD1,ATN1,DNM1L,TSPAN5,EEF1A2,OPTN,EGFR,ABI2,MTSS1L,EPS8,ERBB2,F3,WAC,SH3YL1,TBC1D16,TUBA1B,PTK2B,DLC1,RACK1,STRADA,KAT8,FER,MAD2L2,FGR,PRKAG2,AGAP2,RGPD5,ZMYND15,FOXM1,FOXO3,ANKFY1,NOP56,JKAMP,NBEA,SORBS1,PDLIM5,STAU2,NRG3,BRSK1,FYN,CHL1,CAB39,RAPGEF6,NEK6,NCKAP1,IQGAP2,MYOZ2,GCK,GFAP,USP19,GHR,PPARGC1A,MALT1,GLDC,CBX1,OS9,ATF7,NUDT21,GPR37,RAPGEF4,GRIA1,GRIA2,RFFL,GRIK2,GRIN1,NR3C1,CIT,PTPN5,GSTM5,HMGB1,GABARAPL2,HMGCR,HNRNPK,HPCA,HSPA1L,HSP90AA1,DOCK7,IL6R,INSM1,ITGAV,ITPKA,JAK1,JAK2,METTL21A,KCNH1,KCNH2,KCNQ3,KIT,IPO5,STXBP5,LAMP2,CAMK2N2,LIMS1,SYTL4,PACRG,SMAD1,MAG,MAPT,MBP,MDM4,SHC3,MEF2C,MID1,AFDN,GIT1,JAKMIP3,MYH6,MYO5A,FXYD7,NAP1L1,NCAM1,NCF2,RCOR2,NEFH,NELL1,NELL2,NOS1,NTRK2,KSR2,TBC1D25,OCRL,ODF2,PAK3,PAX6,PDCD2,PDE3B,PDE4D,PDPK1,PFKFB2,PHKG1,PIK3R1,PKD1,SNX10,JAKMIP1,FXYD1,MAPKAP1,STRN3,TNPO2,POLG,PPARA,PTPA,PPP3CA,PPP3CB,RANBP3L,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCB,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,NDUFS7,BCAS3,SYTL2,CNTLN,PTAFR,UHRF1BP1,PTK2,SPDL1,PTPRN,PEX5,NKAIN1,RAB3A,RAB3IL1,RAP1GAP,RASGRF1,RDX,TRIM68,PRIMA1,DCUN1D2,ELP2,FBXW7,SGSM1,PRR5L,LRRK2,RTKN,RXRA,STX1B,RYR1,SAFB,SELL,CASC3,SFPQ,SCAF8,SGK1,PPP1R9A,KIF16B,DOCK10,SHC4,AMBRA1,CNKSR2,SLC4A3,RPH3A,PEX26,RAB3GAP1,SIRT2,CDK5RAP3,CCDC88A,SLC12A4,ELMO2,SLN,SMARCA4,CDK5RAP2,RCOR3,IGSF9B,RIMS1,SNCA,USP33,WDTC1,SP2,KDM4C,ERC1,CDK19,SPART,CLASP2,CAMTA2,MAPK8IP3,STAU1,CEP68,STX1A,STXBP1,NSFL1C,SYT11,FGD4,SUPT5H,PLCB1,SYN1,MMS19,TAF9,TAL1,WWC1,SMG6,ACSL6,DMXL2,TCF7L2,TPCN2,USP22,SYNE1,DOCK9,TNS2,SIRT1,AKTIP,TIAM1,NACC2,TIMP4,CBX5,NR2E1,HEY2,DAAM2,TNFRSF1B,PARD3,CABIN1,RASD2,ZNF346,TRIO,TSC2,UBC,UBE2H,UCHL1,TOM1L2,MICAL1,TBC1D15,RICTOR,XPO1,ELFN1,CRB2,SPHK2,WNK1,MAP3K12,EVI5,PPP1R3F,PLSCR4" GO: Molecular Function GO:0030554 adenyl nucleotide binding 8.05E-06 2.14E-02 3.97E-04 3.36E-03 345 1530 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,DGKD,CDK10,PDXK,CASK,CDK13,STK33,DNAH17,MARK4,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,CLCN4,ABCG2,MAP4K4,AKAP7,SMARCAL1,BAG4,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,AK5,KIF19,DMPK,DNAH9,RPS6KL1,GNE,DYRK1A,FARSB,ABCC5,ABCC9,AASDH,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,NEK6,IP6K3,ATP8A2,ACSS1,GART,GCK,SRCAP,GK,TTBK1,GLUL,DCLK2,GRK4,RAPGEF4,CIT,KIF3A,BVES,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,NIM1K,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,HCN1,NTRK2,NTRK3,DDR2,KSR2,P2RX7,P2RY1,PAK3,PC,CDK18,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,PTPA,PPP5C,PRKACB,PRKAR1B,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RNASEL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,TTBK2,ACSBG1,ABCC8,SYN1,SYN2,POPDC3,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,TIE1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0035091 phosphatidylinositol binding 1.00E-05 2.67E-02 4.85E-04 4.11E-03 66 217 "ACTN2,SNX30,ESYT2,SNX32,WDR35,OSBPL8,OGT,FGD2,PHF12,AMER3,ZFYVE28,CADPS,BTK,HIP1R,KRIT1,SCARB1,ARHGAP33,ZFYVE9,ARHGAP32,FRMPD4,ZFYVE16,SNAP91,SNX29,PLEKHA1,EPB41,MTSS1L,CLVS1,RPS6KC1,SH3YL1,ANKFY1,IQGAP2,GAP43,ARFIP1,WASHC2A,FERMT2,ADAP1,TNFAIP8L3,SCIN,CLVS2,MARK1,NRGN,HCN1,PIRT,PIK3C2A,SNX10,PLCD1,MAPKAP1,SYTL2,PXK,SNX22,AMER2,KIF16B,RPH3A,CCDC88A,PLCB1,SYT1,MCF2L,ARHGAP9,ATP13A2,PARD3,TTPA,TUB,SGK3,SNX27,MPPE1,SNX14" GO: Molecular Function GO:0032555 purine ribonucleotide binding 1.05E-05 2.80E-02 5.01E-04 4.24E-03 411 1864 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,CNGA3,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,RAPGEF4,CIT,KIF3A,BVES,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,HCN1,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKAR1B,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,POPDC3,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0032553 ribonucleotide binding 1.45E-05 3.85E-02 6.76E-04 5.72E-03 413 1880 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,CNGA3,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,RAPGEF4,CIT,KIF3A,BVES,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,CREG2,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NOS1,NPR2,HCN1,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKAR1B,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,POPDC3,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0017076 purine nucleotide binding 1.79E-05 4.76E-02 8.21E-04 6.95E-03 412 1879 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,HCN2,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,CNGA3,AKAP7,SMARCAL1,BAG4,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,RAPGEF4,CIT,KIF3A,BVES,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,HCN1,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKAR1B,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,POPDC3,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0035254 glutamate receptor binding 1.92E-05 5.11E-02 8.66E-04 7.33E-03 21 46 "ADORA2A,ADRB2,ATP2B2,CALM1,CAMK2A,CANX,HOMER3,DLG2,DLG3,DLG4,SHANK1,CACNG2,GNAS,GRIN1,PTPN5,OPHN1,RASGRF1,SYNDIG1,SHANK2,NETO2,NETO1" GO: Molecular Function GO:0005272 sodium channel activity 2.58E-05 6.88E-02 1.15E-03 9.70E-03 18 37 "ASIC2,ASIC1,SHROOM2,HCN2,ASIC3,KCNK1,HCN1,NALCN,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SCN3B,TRPM2" GO: Molecular Function GO:0022824 transmitter-gated ion channel activity 2.86E-05 7.61E-02 1.23E-03 1.04E-02 15 28 "GRIN3A,PTK2B,GABRB3,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" GO: Molecular Function GO:0022835 transmitter-gated channel activity 2.86E-05 7.61E-02 1.23E-03 1.04E-02 15 28 "GRIN3A,PTK2B,GABRB3,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" GO: Molecular Function GO:0008179 adenylate cyclase binding 2.98E-05 7.93E-02 1.26E-03 1.07E-02 9 12 "ADCY2,ADCY5,ADCYAP1R1,ADRB2,CALM1,AKAP6,AKAP5,AKAP12,GRIA1" GO: Molecular Function GO:0019900 kinase binding 3.80E-05 1.01E-01 1.56E-03 1.32E-02 168 691 "ADCY6,ADD3,AXIN2,SLC12A5,KIDINS220,AP2A1,AP2A2,AP1B1,TBC1D14,PLA2G6,TAOK1,ANK2,APC,USP37,ARHGDIA,ARRB1,RGS20,ARRB2,CADPS,DACT3,ATP1A1,BARD1,KSR1,CDK5R1,ARHGEF7,CACNB2,CACNB4,DIRAS1,CALM1,CAMK2B,BRSK2,SPAG9,PRC1,CDC25B,CDC42,CDH2,COPB2,TAOK2,CLTC,FBXO7,PICK1,AKAP7,AKAP5,CRY2,FEZ1,SIPA1L1,SOCS5,PITPNM3,APPL1,CTNND1,DOCK4,HDAC9,HDAC4,MAML1,JAKMIP2,SNAP91,PARD6A,SV2A,DLG2,DLG3,DLG4,DNM1,DNM2,SLC12A6,DPYSL2,ATN1,EEF1A2,EGFR,ABI2,PTK2B,RACK1,STRADA,FER,MAD2L2,FGR,PRKAG2,AGAP2,FOXM1,FOXO3,NBEA,SORBS1,PDLIM5,STAU2,NRG3,BRSK1,CAB39,NEK6,GFAP,GHR,ATF7,GRIA1,GRIA2,RFFL,NR3C1,PTPN5,GSTM5,HPCA,HSP90AA1,ITGAV,JAK2,KCNH1,KCNQ3,CAMK2N2,LIMS1,SMAD1,MAG,MAPT,SHC3,JAKMIP3,MYH6,NAP1L1,NEFH,NELL1,NELL2,NTRK2,KSR2,PAX6,PDE3B,PDPK1,PFKFB2,PIK3R1,PKD1,JAKMIP1,MAPKAP1,PRKAB2,PKIA,PRKAR1B,PRKCB,PRKCZ,MAPK4,MAPK7,MAPK9,CNTLN,PTAFR,PTK2,RAB3IL1,RASGRF1,ELP2,STX1B,SAFB,SGK1,PPP1R9A,SHC4,CNKSR2,CDK5RAP3,CCDC88A,SLC12A4,ELMO2,CDK5RAP2,IGSF9B,RIMS1,CLASP2,MAPK8IP3,CEP68,STX1A,STXBP1,SYN1,WWC1,TCF7L2,TPCN2,TNS2,SIRT1,TIAM1,PARD3,TOM1L2,RICTOR,WNK1,MAP3K12" GO: Molecular Function GO:0005230 extracellular ligand-gated ion channel activity 3.81E-05 1.02E-01 1.56E-03 1.32E-02 29 76 "P2RX6,CHRNA4,CHRNB2,GRIN3A,PTK2B,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,P2RX7,SLC17A7" GO: Molecular Function GO:0022853 active ion transmembrane transporter activity 3.98E-05 1.06E-01 1.61E-03 1.36E-02 54 175 "SLC12A5,SLC24A4,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,SLC22A6,SLC24A2,SLC4A7,SLC4A8,SLC12A6,ABCC5,ABCC9,ATP8A1,SLC9B2,PCYOX1,ATP13A4,SLC37A3,ATP6V1H,ATP2C1,SLC10A4,SLC26A11,SLC6A15,SLC1A2,SLC4A3,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,ABCC8,SLC37A2,ATP13A2,SLC13A3,ATP6V0E2,SLC26A10,SLC17A7,SLC4A10" GO: Molecular Function GO:0017075 syntaxin-1 binding 4.10E-05 1.09E-01 1.63E-03 1.38E-02 12 20 "SNPH,DAPK1,CPLX2,CPLX1,STXBP5,MYO5A,LRRK2,SYBU,SNAP25,STXBP1,SYP,SYT1" GO: Molecular Function GO:0031420 alkali metal ion binding 4.66E-05 1.24E-01 1.83E-03 1.55E-02 13 23 "SLC24A4,PDXK,ATP1A1,ATP1A2,CAPN3,SLC24A2,HDAC4,KCNA4,KCNJ11,PKM,SCN2A,SCN3A,SCN8A" GO: Molecular Function GO:0008047 enzyme activator activity 4.79E-05 1.28E-01 1.85E-03 1.56E-02 130 515 "RALGAPA1,ABR,AXIN2,AGT,TBC1D14,TAOK1,ARHGAP20,OGT,APAF1,ALS2,APOC1,APOC2,APP,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ATP1B3,ADGRB3,RGS11,RGS9,CFLAR,CDK5R1,CDK5R2,CALM1,KALRN,ARHGEF1,ARHGAP33,EVI5L,CHM,CHN1,CHN2,ARHGAP22,PLAA,ARHGEF6,RGS6,SIPA1L1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,B3GAT3,TIAM2,SRGAP3,SGSM2,RABGAP1L,DOCK2,CASP8AP2,ABI1,DNAJB6,FAM13A,RASA4,RGS17,PCOLCE2,TBC1D16,DLC1,RACK1,STRADA,FGF13,PRKAG2,AGAP2,AGAP3,ARFGAP2,NRG3,CAB39,IQGAP2,MALT1,RUNDC3A,DBF4,ADAP1,ARHGAP19,NCKAP1L,ARHGAP36,HMGB1,AGFG1,SMAP1,IGF1,INPP5B,STXBP5,ARHGAP12,MIA2,MMP16,MMP17,GIT1,DBNL,MT3,MYO9A,NF1,TBC1D25,OCRL,OPHN1,PDPK1,PLXNB1,PTPA,MAPK9,BCAS3,RAB3A,RAP1GAP,RAP1GDS1,RGS3,RGS4,RGS7,RGS10,RGS12,RIC8B,SGSM1,LRRK2,ELMOD1,RASA3,ITSN1,ASAP3,PREX2,RAB3GAP1,ARFGAP1,ARHGAP26,RAP1GAP2,PLCB1,AZIN2,ARHGEF12,ARHGAP9,TSC2,BCL2L13,TBC1D15,RICTOR,EVI5" GO: Molecular Function GO:0015277 kainate selective glutamate receptor activity 4.87E-05 1.30E-01 1.86E-03 1.57E-02 6 6 "GRIA2,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" GO: Molecular Function GO:0019901 protein kinase binding 5.67E-05 1.51E-01 2.13E-03 1.80E-02 152 620 "ADCY6,ADD3,AXIN2,SLC12A5,KIDINS220,AP2A1,AP2A2,AP1B1,TBC1D14,PLA2G6,TAOK1,ANK2,APC,USP37,ARHGDIA,ARRB1,RGS20,ARRB2,CADPS,DACT3,ATP1A1,KSR1,CDK5R1,ARHGEF7,CACNB2,CACNB4,DIRAS1,CALM1,CAMK2B,BRSK2,SPAG9,PRC1,CDC25B,CDC42,CDH2,COPB2,TAOK2,CLTC,FBXO7,PICK1,AKAP7,AKAP5,CRY2,FEZ1,SIPA1L1,SOCS5,PITPNM3,APPL1,CTNND1,DOCK4,HDAC9,HDAC4,MAML1,SNAP91,PARD6A,SV2A,DLG4,DNM1,DNM2,SLC12A6,DPYSL2,ATN1,EEF1A2,EGFR,PTK2B,RACK1,FER,MAD2L2,FGR,PRKAG2,AGAP2,FOXM1,FOXO3,NBEA,SORBS1,PDLIM5,STAU2,NRG3,BRSK1,NEK6,GHR,ATF7,GRIA1,GRIA2,RFFL,NR3C1,PTPN5,GSTM5,HSP90AA1,ITGAV,JAK2,KCNH1,KCNQ3,CAMK2N2,LIMS1,SMAD1,MAG,MAPT,SHC3,MYH6,NEFH,NELL1,NELL2,NTRK2,KSR2,PAX6,PDE3B,PDPK1,PFKFB2,PIK3R1,PKD1,MAPKAP1,PRKAB2,PKIA,PRKAR1B,PRKCB,PRKCZ,MAPK4,MAPK7,MAPK9,CNTLN,PTAFR,PTK2,RASGRF1,ELP2,STX1B,SAFB,SGK1,PPP1R9A,SHC4,CNKSR2,CDK5RAP3,CCDC88A,SLC12A4,ELMO2,CDK5RAP2,RIMS1,CLASP2,MAPK8IP3,CEP68,STXBP1,SYN1,TCF7L2,TPCN2,TNS2,SIRT1,TIAM1,PARD3,TOM1L2,RICTOR,WNK1,MAP3K12" GO: Molecular Function GO:0015085 calcium ion transmembrane transporter activity 5.85E-05 1.56E-01 2.16E-03 1.83E-02 43 132 "SLC24A4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,SLC24A2,GRIN3A,CACNG7,CACNG3,CACNG2,ATP13A4,ATP2C1,GPM6A,GRIN1,CACFD1,GRM7,IL1RAPL1,ITGAV,SLC11A2,PDE2A,PKD1,RYR1,RYR3,RASA3,SLC8A2,SLC8A1,SLC8A3,TPCN2,TRPC1,TRPC3,TRPM2,JPH3" GO: Molecular Function GO:0016772 "transferase activity, transferring phosphorus-containing groups" 6.12E-05 1.63E-01 2.23E-03 1.89E-02 232 1006 "KCNH8,CLK4,CDC7,NME5,AK2,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,CDK13,STK33,MARK4,ATM,RIPK1,FGF17,NRP2,KSR1,BMPR1B,CDK5R1,BTK,MMD2,DDR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,ISPD,CCNH,CCNT1,CD86,DGKI,CDK11B,DCLK1,TBRG4,TAOK2,TJP2,MAP4K4,PCYT1B,NRG2,CDC42BPB,AATK,CSF1R,CSF2RA,CSNK1E,CSNK1G3,FGFR1OP2,RASSF2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,AK5,DLG2,DLG3,DLG4,DMPK,RPS6KL1,GNE,DYRK1A,EDNRA,SGK2,HIPK3,EFNA3,EFNB3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,EFEMP1,STRADA,TESK2,FER,FGF1,POLR1B,FGFR1,FGFR3,FGR,PRKAG2,POLK,IP6K2,FLT1,AK8,TPK1,NPTN,CAMKK2,MPP6,BRSK1,FYN,GAB1,CAB39,NEK6,IP6K3,GCK,GK,TTBK1,CRCP,DBF4,POLL,DCLK2,GRK4,CNTRL,CIT,FICD,MAP4K5,IRAK3,HSP90AA1,MYLK2,NIM1K,NME9,ITPKA,ITPKB,JAK1,JAK2,KCNH1,KCNH2,KHK,KIT,MARK1,MARK3,MATK,KITLG,MPP2,STK32C,NRBP2,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,PHKG1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKM,PRIMPOL,POLG,POLR2F,CRLS1,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRPSAP2,RELN,SNRK,PIGG,PTK2,PXK,STK32A,RET,REV3L,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,HKDC1,MAGI3,SEPHS1,MAST1,TNIK,NMNAT2,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TGFBR3,TIE1,TK2,PIK3R5,CDK20,TRIO,SGK3,VAV1,SPHK2,POLR3H,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" GO: Molecular Function GO:0004714 transmembrane receptor protein tyrosine kinase activity 6.76E-05 1.80E-01 2.44E-03 2.06E-02 26 67 "ALK,NRP2,DDR1,NRG2,CSF1R,EFNA3,EFNB3,EGFR,EPHA5,EPHB1,ERBB2,ERBB4,EFEMP1,FGFR1,FGFR3,FLT1,NPTN,KIT,NTRK2,NTRK3,DDR2,PDGFRA,RET,EPHA10,TEK,TIE1" GO: Molecular Function GO:0032549 ribonucleoside binding 7.24E-05 1.93E-01 2.54E-03 2.15E-02 397 1831 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,POLR1B,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,CIT,KIF3A,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0001883 purine nucleoside binding 7.24E-05 1.93E-01 2.54E-03 2.15E-02 397 1831 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,ADORA1,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,CIT,KIF3A,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0001882 nucleoside binding 7.96E-05 2.12E-01 2.70E-03 2.28E-02 398 1838 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,ADORA1,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,POLR1B,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,CIT,KIF3A,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0030506 ankyrin binding 7.97E-05 2.12E-01 2.70E-03 2.28E-02 12 21 "SPTBN4,ATP1A1,CACNA1D,CLTC,FLNC,KCNJ11,KCNQ2,KCTD6,NRCAM,PLEC,SLC8A1,SPTB" GO: Molecular Function GO:0032550 purine ribonucleoside binding 8.01E-05 2.13E-01 2.70E-03 2.28E-02 396 1828 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,AKAP7,SMARCAL1,HS3ST5,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,CIT,KIF3A,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,PYGM,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,GAL3ST4,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,GAL3ST3,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0016595 glutamate binding 8.09E-05 2.16E-01 2.70E-03 2.28E-02 9 13 "CPS1,GAD1,GAD2,GLUL,GRIK1,GRIN1,GRIN2D,GRM7,SLC1A3" GO: Molecular Function GO:0019905 syntaxin binding 8.38E-05 2.23E-01 2.76E-03 2.33E-02 34 98 "SYT13,DOC2A,STX16,CACNA1A,SYT6,SNPH,DAPK1,BLOC1S6,ABCC9,SYT15,SYT3,SYT17,CPLX2,CPLX1,C2CD4C,STXBP5,SYTL4,SYT9,MYO5A,SYTL2,LRRK2,SYBU,RPH3A,NAPB,SNAP25,SPTAN1,STXBP1,SYT11,ABCC8,SYP,SYT1,SYT4,SYT5,STXBP4" GO: Molecular Function GO:0000149 SNARE binding 8.66E-05 2.31E-01 2.81E-03 2.38E-02 43 134 "ADCY6,SYT13,DOC2A,STX16,CACNA1A,SYT6,SNPH,DAPK1,BLOC1S6,ABCC9,SYT15,STX2,VTI1B,SYT3,SYT17,CPLX2,CPLX1,GABARAPL2,C2CD4C,KCNB1,STXBP5,SYTL4,SYT9,MYO5A,SYTL2,LRRK2,STX1B,SYBU,RPH3A,NAPB,SNAP25,SPTAN1,STX1A,STXBP1,SYT11,ABCC8,VAMP1,SYP,SYT1,SYT4,SYT5,STXBP4,TRIM9" GO: Molecular Function GO:0004674 protein serine/threonine kinase activity 9.01E-05 2.40E-01 2.89E-03 2.45E-02 115 452 "CLK4,CDC7,TAOK1,LTBP4,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,ATM,RIPK1,BMPR1B,CDK5R1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CCNH,CCNT1,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,ERCC2,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,TESK2,PRKAG2,CAMKK2,BRSK1,CAB39,NEK6,TTBK1,DBF4,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,ITPKA,MARK1,MARK3,STK32C,NRBP2,NEK1,KSR2,PAK3,CDK18,PDPK1,CDK14,PHKG1,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,STK32A,NEK11,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TGFBR3,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" GO: Molecular Function GO:0005524 ATP binding 1.01E-04 2.68E-01 3.19E-03 2.70E-02 325 1475 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,DGKD,CDK10,PDXK,CASK,CDK13,STK33,DNAH17,MARK4,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,DCLK1,MAGI1,UBE2L6,TAOK2,CLCN3,CLCN4,ABCG2,MAP4K4,SMARCAL1,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,AK5,KIF19,DMPK,DNAH9,RPS6KL1,GNE,DYRK1A,FARSB,ABCC5,ABCC9,AASDH,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,PTK2B,TAOK3,ATP8A1,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,ATP13A4,FLT1,SMC2,AK8,TPK1,CAMKK2,ATP2C1,BRSK1,FYN,NEK6,IP6K3,ATP8A2,ACSS1,GART,GCK,SRCAP,GK,TTBK1,GLUL,DCLK2,GRK4,CIT,KIF3A,FICD,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,NIM1K,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,PTPA,PPP5C,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,CNNM2,SNRK,PTK2,PXK,STK32A,ACSM5,ACSS3,RAD17,RAD51D,NWD1,RET,FIGN,TTLL7,KIF7,RNASEL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,MAPK12,SARS,SCN8A,KIF27,HSPA4L,SGK1,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,TTBK2,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,TIE1,TK2,ERCC6L2,CDK20,TRIO,SGK3,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0005245 voltage-gated calcium channel activity 1.20E-04 3.21E-01 3.77E-03 3.19E-02 19 44 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG3,CACNG2,GRM7,IL1RAPL1,ITGAV,RYR1,TPCN2" GO: Molecular Function GO:0003774 motor activity 1.29E-04 3.43E-01 3.99E-03 3.37E-02 42 132 "KIF6,MYH7B,DNAH17,DYNLL1,KIF1A,MYL6B,KIF26A,DCTN1,KIF19,DNAH9,DYNC1I1,DCTN2,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,DNHD1,KIF7,MYH14,KIF27,KIF21A,KIF16B,MYO18A,MYH15,KIF13A,MYO16,KIF21B,KIF1B,DNAH7,KLC2,DNALI1,DNAH10" GO: Molecular Function GO:1901981 phosphatidylinositol phosphate binding 1.31E-04 3.48E-01 4.00E-03 3.39E-02 41 128 "ACTN2,OSBPL8,OGT,FGD2,AMER3,ZFYVE28,CADPS,BTK,KRIT1,FRMPD4,ZFYVE16,PLEKHA1,MTSS1L,CLVS1,ANKFY1,IQGAP2,GAP43,ARFIP1,WASHC2A,FERMT2,ADAP1,SCIN,CLVS2,MARK1,NRGN,HCN1,PIRT,PLCD1,MAPKAP1,SYTL2,AMER2,KIF16B,RPH3A,PLCB1,SYT1,ARHGAP9,ATP13A2,PARD3,TTPA,SNX27,SNX14" GO: Molecular Function GO:0031267 small GTPase binding 1.40E-04 3.73E-01 4.24E-03 3.59E-02 81 301 "FMNL2,ADCYAP1R1,HACE1,TBC1D14,FGD2,ALS2,ARHGDIA,DOCK11,WASF1,FMNL3,DGKI,ARHGEF2,EVI5L,CHM,MYRIP,CDC42BPB,RIMS2,USP6NL,DOCK4,TBC1D5,DAPK3,RUSC2,PARD6A,SRGAP3,SGSM2,RABGAP1L,OPTN,ABI2,MTSS1L,EPS8,TBC1D16,FER,RGPD5,ANKFY1,RAPGEF6,NCKAP1,IQGAP2,RAPGEF4,GRIA1,CIT,DOCK7,ITPKA,IPO5,STXBP5,SYTL4,AFDN,GIT1,MYO5A,NCF2,TBC1D25,OCRL,ODF2,PAK3,MAPKAP1,TNPO2,RANBP3L,SYTL2,PEX5,RAP1GAP,RASGRF1,SGSM1,LRRK2,RTKN,KIF16B,DOCK10,RPH3A,RAB3GAP1,RIMS1,USP33,ERC1,FGD4,DMXL2,DOCK9,TIAM1,DAAM2,TSC2,MICAL1,TBC1D15,XPO1,SPHK2,EVI5" GO: Molecular Function GO:0035639 purine ribonucleoside triphosphate binding 1.44E-04 3.84E-01 4.32E-03 3.66E-02 391 1815 "ABCF1,SYN3,ACLY,CLK4,ADCY2,ADCY5,ADCY6,ADCY8,CDC7,AK2,HFM1,TAOK1,ABCD2,CARNS1,ALK,KIF6,CDC42BPA,EP400,MAP4K3,MYH7B,APAF1,DGKZ,UPRT,DGKD,CDK10,PDXK,CASK,ARHGAP5,CDK13,STK33,DNAH17,MARK4,RASL11B,DDX3Y,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,KIF1A,TTLL9,BCS1L,BLM,KSR1,BMPR1B,BTK,RAB29,CACNA1B,DDR1,DIRAS1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,P2RX6,ENTPD2,DGKI,CDK11B,SEPT7,CDC42,DCLK1,MAGI1,UBE2L6,RAB3C,TAOK2,RAB33A,RAB28,CLCN3,CLCN4,ABCG2,MAP4K4,RAB26,SMARCAL1,CHD1L,CPS1,CDC42BPB,ABCG1,AATK,CSF1R,CSNK1E,CSNK1G3,CHD5,PNPLA8,KATNAL2,EARS2,KIF26A,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DDX46,RHOBTB1,AK5,KIF19,RAB39B,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,GNE,DYRK1A,FARSB,ABCC5,DNM1L,ABCC9,AASDH,ATL1,EEF1A2,SGK2,HIPK3,EGFR,EIF5,IRAK4,TNK2,SRPK3,PAN3,TUBD1,EPHA5,EPHB1,GPHN,RAB9B,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,RASL12,RRAGB,KATNAL1,HSPA12B,ABCA8,RPS6KC1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,PRKAG2,UBE2E3,IP6K2,AGAP2,AGAP3,ATP13A4,FLT1,SMC2,AK8,TPK1,RASL10A,CAMKK2,ATP2C1,BRSK1,FYN,HBS1L,NEK6,IP6K3,SEPT9,ATP8A2,ACSS1,GART,GCK,TUBA8,SRCAP,GK,TTBK1,RND1,RAB30,GLUL,DCLK2,RAB40B,GNAL,GNAO1,GNAS,GRK4,TUBA1C,CIT,KIF3A,FICD,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,MAP4K5,IRAK3,UBE2QL1,DDX19B,DHX35,HSPA1L,HSP90AA1,MYLK2,RAB41,NIM1K,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KCNJ10,KCNJ11,KHK,KIF2A,KIF5A,KIF5C,KIFC3,KIT,LIG4,MARK1,MARK3,MAT2A,MATK,MOV10,STK32C,NRBP2,DDX25,MX1,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,IDNK,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPA1,P2RX7,P2RY1,PAK3,PC,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,CDK14,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PKM,PMS2,SEPT4,PTPA,PPP5C,PRKACB,PRKCB,RAB39A,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,CNNM2,PSMA6,SNRK,PTK2,PXK,STK32A,ACSM5,RAB3A,RAB5B,ACSS3,RAD17,RAD51D,NWD1,RET,FIGN,TTLL7,KIF7,RIT2,RNASEL,RERGL,MYH14,NEK11,EPHA10,ATP8B4,RIMKLA,RPS6KA2,STK32B,LRRK2,ABCA11P,HUNK,RTKN,MAPK12,SARS,SCN8A,MRAS,KIF27,HSPA4L,SGK1,SCG5,KIF21A,KIF16B,MYO18A,HKDC1,MAGI3,CHD9,NUBPL,URGCP,DHX30,SEPHS1,SLC22A4,NAXD,SMARCA4,MAST1,MYH15,KIF13A,MYO16,TNIK,KIF21B,NMNAT2,KIF1B,CDK19,SRPK2,ATP10B,NEK4,SEPT8,TTBK2,SEPT3,ACSBG1,ABCC8,SYN1,SYN2,ATP11A,ACSL6,SIK3,TEK,ATP13A2,DNAH7,DICER1,ARL10,TIE1,TK2,ERCC6L2,RASD2,CDK20,TRIO,TUBB2A,SGK3,TUBB1,UBE2H,WRN,KCNT2,SPHK2,SMARCAD1,DHX33,WNK1,MAP3K12,TUBA1A,NAV3,NAV2,ITM2C,WNK3,WNK2,DNAH10,PAK5,CAMK1G,ACTR3B,NLRP3" GO: Molecular Function GO:0008289 lipid binding 1.76E-04 4.69E-01 5.22E-03 4.42E-02 166 701 "ACTN2,SNX30,ESYT2,AP2A2,SNX32,OSBPL1A,OSBPL6,WDR35,OSBPL8,SYT13,DOC2A,PITPNM2,AMPH,OGT,FGD2,PHF12,ANXA7,DGKD,APOC1,APOC2,AMER3,SPTBN4,ZFYVE28,ARHGDIA,PLA2G4C,CADPS,ATP1A1,ATP1A2,ATP1A3,BTK,CDK5R2,CALB1,SYT6,HIP1R,KRIT1,SCARB1,ARHGAP33,CPNE6,ZFYVE9,ACBD5,CPS1,CLIP3,ABCG1,OSBPL3,PITPNM3,ARHGAP32,FRMPD4,ZFYVE16,DBI,PITPNC1,SNAP91,DNM1L,SNX29,SYT15,RASGRP1,SH3GLB1,PLEKHA1,EPB41,RASGRP2,MTSS1L,F3,CLVS1,FABP7,RPS6KC1,SH3YL1,PRAM1,DLC1,FER,ANKFY1,PSD2,SGIP1,SYT3,RAPGEF6,IQGAP2,GAP43,SYT17,STARD10,ARFIP1,WASHC2A,STARD3,FERMT2,GPR12,ADAP1,LPAR4,GPER1,PCLO,NR3C1,GSTM5,PACSIN2,TNFAIP8L3,HMGB1,IGF1,SCIN,C2CD4C,CLVS2,SYTL4,MARK1,SYT9,MTTP,NF1,NME4,NRGN,HCN1,OPHN1,P2RX7,TREM2,PIRT,PIK3C2A,SNX10,PLCB2,PLCD1,PLIN1,EPN1,PLTP,PMP2,MAPKAP1,PACSIN1,PPARA,PPP5C,PSD,SYTL2,LAMA1,PTAFR,PTCH1,PXK,RLBP1,RPE65,SNX22,PAQR6,AMER2,SCP2,SELL,SH3GL2,SH3GL3,KIF16B,RPH3A,EPN2,CCDC88A,SNCA,FNBP1,ARHGAP26,APOM,NSFL1C,SYT11,PLCB1,SYP,SYT1,SYT4,SYT5,MCF2L,ARHGAP9,ATP13A2,TIAM1,TLR4,PARD3,TNR,TTPA,TUB,SGK3,PDIA2,PITPNB,OSBP2,SNX27,MPPE1,MVB12B,SNX14" GO: Molecular Function GO:0005200 structural constituent of cytoskeleton 2.03E-04 5.41E-01 5.95E-03 5.04E-02 36 110 "ADD3,ANK1,ANK2,ANK3,SPTBN4,MYOM1,INA,MYOM2,DMD,SORBS3,TUBD1,EPB41,TUBA1B,TUBB3,TUBB4A,ACTL6B,TUBGCP4,TUBA8,GFAP,TUBA1C,TUBB2B,MAPT,MYBPC1,NEFM,NEFH,ODF2,PLEC,EPB41L4B,SPTAN1,SPTB,EPB41L3,ERBIN,TPM1,TUBB2A,TUBB1,TUBA1A" GO: Molecular Function GO:0051020 GTPase binding 2.07E-04 5.52E-01 6.00E-03 5.08E-02 86 327 "FMNL2,ADCYAP1R1,HACE1,TBC1D14,BIN1,FGD2,ALS2,ARHGDIA,DOCK11,WASF1,FMNL3,DGKI,ARHGEF2,EVI5L,CHM,MYRIP,CDC42BPB,RIMS2,USP6NL,DOCK4,TBC1D5,DAPK3,RUSC2,PARD6A,SRGAP3,SGSM2,RABGAP1L,OPTN,ABI2,MTSS1L,EPS8,TBC1D16,FER,RGPD5,ANKFY1,RAPGEF6,NCKAP1,IQGAP2,RAPGEF4,GRIA1,CIT,HSP90AA1,DOCK7,ITPKA,IPO5,STXBP5,SYTL4,AFDN,GIT1,MYO5A,NCF2,TBC1D25,OCRL,ODF2,PAK3,MAPKAP1,TNPO2,RANBP3L,SYTL2,PTPRN,PEX5,RAB3A,RAP1GAP,RASGRF1,SGSM1,LRRK2,RTKN,PPP1R9A,KIF16B,DOCK10,RPH3A,RAB3GAP1,RIMS1,USP33,ERC1,FGD4,DMXL2,DOCK9,TIAM1,DAAM2,TSC2,MICAL1,TBC1D15,XPO1,SPHK2,EVI5" GO: Molecular Function GO:0017048 Rho GTPase binding 2.41E-04 6.43E-01 6.92E-03 5.85E-02 30 87 "FMNL2,HACE1,ALS2,ARHGDIA,DOCK11,WASF1,FMNL3,ARHGEF2,CDC42BPB,DOCK4,DAPK3,PARD6A,SRGAP3,ABI2,MTSS1L,EPS8,NCKAP1,IQGAP2,CIT,DOCK7,ITPKA,NCF2,OCRL,PAK3,LRRK2,RTKN,DOCK10,DOCK9,TIAM1,DAAM2" GO: Molecular Function GO:0051015 actin filament binding 2.74E-04 7.30E-01 7.76E-03 6.57E-02 41 132 "ACTN1,ACTN2,ADD1,ADD2,ERMN,BIN1,GAS7,SHTN1,SHROOM2,CACNB2,PICK1,SIPA1L1,AIF1L,DBN1,BLOC1S6,USH1C,EGFR,RCSD1,CORO2B,FLNC,IQGAP2,SCIN,DBNL,CTNNA3,MYH3,MYO6,MYO7A,MYH14,PPP1R9A,MYO18A,PKNOX2,MYO16,SPTB,CLASP2,ITPRID2,FGD4,SYNE2,SYNE1,TMOD1,WIPF1,WIPF2" GO: Molecular Function GO:0030594 neurotransmitter receptor activity 3.28E-04 8.75E-01 9.21E-03 7.79E-02 25 69 "CHRM1,CHRM4,CHRNA4,CHRNB2,GRIN3A,DRD1,PTK2B,GABRA2,GABRA3,GABRA4,GABRB3,GABRG2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,HRH3" GO: Molecular Function GO:0030552 cAMP binding 3.93E-04 1.00E+00 1.09E-02 9.22E-02 13 27 "HCN2,RAPGEF4,BVES,HCN1,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PRKAR1B,POPDC3" GO: Molecular Function GO:0030955 potassium ion binding 3.97E-04 1.00E+00 1.09E-02 9.22E-02 9 15 "SLC24A4,PDXK,ATP1A1,ATP1A2,SLC24A2,HDAC4,KCNA4,KCNJ11,PKM" GO: Molecular Function GO:0015459 potassium channel regulator activity 4.67E-04 1.00E+00 1.27E-02 1.07E-01 19 48 "ADRB2,DPP10,KCNAB2,KCNAB3,DPP6,ABCC9,SGK2,KCNMB2,KCNMB4,KCNK2,PRKCZ,KCNIP3,KCNIP2,KCNIP1,SGK1,KCNE5,SGK3,WNK1,KCNAB1" GO: Molecular Function GO:0033130 acetylcholine receptor binding 4.93E-04 1.00E+00 1.33E-02 1.12E-01 7 10 "APP,ATP2B2,NRXN1,UBXN2A,LYPD1,DLG4,JAK2" GO: Molecular Function GO:0017016 Ras GTPase binding 5.29E-04 1.00E+00 1.41E-02 1.19E-01 74 281 "FMNL2,HACE1,TBC1D14,ALS2,ARHGDIA,DOCK11,WASF1,FMNL3,DGKI,ARHGEF2,EVI5L,CHM,MYRIP,CDC42BPB,RIMS2,USP6NL,DOCK4,TBC1D5,DAPK3,RUSC2,PARD6A,SRGAP3,SGSM2,RABGAP1L,OPTN,ABI2,MTSS1L,EPS8,TBC1D16,FER,RGPD5,ANKFY1,RAPGEF6,NCKAP1,IQGAP2,RAPGEF4,CIT,DOCK7,ITPKA,IPO5,STXBP5,SYTL4,AFDN,MYO5A,NCF2,TBC1D25,OCRL,ODF2,PAK3,MAPKAP1,TNPO2,RANBP3L,SYTL2,RAP1GAP,RASGRF1,SGSM1,LRRK2,RTKN,KIF16B,DOCK10,RPH3A,RAB3GAP1,RIMS1,USP33,ERC1,DMXL2,DOCK9,TIAM1,DAAM2,MICAL1,TBC1D15,XPO1,SPHK2,EVI5" GO: Molecular Function GO:0045499 chemorepellent activity 6.11E-04 1.00E+00 1.61E-02 1.36E-01 13 28 "SEMA6A,SEMA7A,SEMA4G,SLIT2,SEMA3D,SEMA6C,SEMA4D,NRG3,SEMA5B,SEMA6D,SEMA4A,FLRT2,SEMA3B" GO: Molecular Function GO:0030676 Rac guanyl-nucleotide exchange factor activity 6.75E-04 1.00E+00 1.76E-02 1.49E-01 8 13 "ALS2,ARHGEF2,ARHGEF4,DOCK2,PREX2,TIAM1,VAV1,SPATA13" GO: Molecular Function GO:0030215 semaphorin receptor binding 7.39E-04 1.00E+00 1.89E-02 1.60E-01 11 22 "SEMA6A,SEMA7A,SEMA4G,SEMA3D,SEMA6C,SEMA4D,SEMA5B,PLXNB1,SEMA6D,SEMA4A,SEMA3B" GO: Molecular Function GO:0004115 "3',5'-cyclic-AMP phosphodiesterase activity" 7.39E-04 1.00E+00 1.89E-02 1.60E-01 11 22 "PDE8B,ENPP6,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" GO: Molecular Function GO:0031402 sodium ion binding 7.59E-04 1.00E+00 1.93E-02 1.63E-01 9 16 "SLC24A4,PDXK,ATP1A1,ATP1A2,CAPN3,SLC24A2,SCN2A,SCN3A,SCN8A" GO: Molecular Function GO:0072509 divalent inorganic cation transmembrane transporter activity 8.15E-04 1.00E+00 2.05E-02 1.73E-01 49 173 "SLC24A4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,SLC24A2,GRIN3A,CACNG7,CACNG3,CACNG2,ATP13A4,ATP2C1,GPM6A,GRIN1,CACFD1,GRM7,IL1RAPL1,ITGAV,SLC11A2,PDE2A,PKD1,CNNM2,RYR1,RYR3,SLC30A10,RASA3,SLC8A2,SLC8A1,SLC8A3,TPCN2,TRPC1,TRPC3,TRPM2,SLC30A3,SLC30A4,SLC39A12,JPH3" GO: Molecular Function GO:0035255 ionotropic glutamate receptor binding 1.06E-03 1.00E+00 2.61E-02 2.21E-01 12 26 "ADRB2,CANX,DLG2,DLG3,DLG4,SHANK1,CACNG2,GNAS,OPHN1,SHANK2,NETO2,NETO1" GO: Molecular Function GO:1990239 steroid hormone binding 1.06E-03 1.00E+00 2.61E-02 2.21E-01 5 6 "ATP1A1,ATP1A2,ATP1A3,GPER1,NR3C1" GO: Molecular Function GO:0048306 calcium-dependent protein binding 1.07E-03 1.00E+00 2.61E-02 2.21E-01 24 70 "ANXA7,CALM1,SYT6,NRXN1,CABP1,PDCD6IP,STX2,CPLX2,STMN2,SPACA9,GRM7,MYO5A,HNRNPM,MASP1,KCNIP3,S100B,SEC31A,SNAP25,STX1A,SYN1,SYN2,SYT1,VLDLR,LRP8" GO: Molecular Function GO:0042577 lipid phosphatase activity 1.14E-03 1.00E+00 2.76E-02 2.34E-01 7 11 "PLPPR4,INPP5K,PLPP7,PLPPR1,PLPPR3,PLPPR2,PLPPR5" GO: Molecular Function GO:0001786 phosphatidylserine binding 1.15E-03 1.00E+00 2.76E-02 2.34E-01 14 33 "OSBPL8,SCARB1,CPNE6,RASGRP1,SYT3,GAP43,HMGB1,SCIN,MARK1,PLCD1,SYTL2,RPE65,SYT1,SYT4" GO: Molecular Function GO:0016776 "phosphotransferase activity, phosphate group as acceptor" 1.26E-03 1.00E+00 3.00E-02 2.54E-01 17 44 "NME5,AK2,CASK,TJP2,IP6K1,AK5,DLG2,DLG3,DLG4,IP6K2,AK8,MPP6,IP6K3,NME9,MPP2,NME4,MAGI3" GO: Molecular Function GO:0019199 transmembrane receptor protein kinase activity 1.30E-03 1.00E+00 3.06E-02 2.59E-01 29 91 "LTBP4,ALK,NRP2,BMPR1B,DDR1,NRG2,CSF1R,EFNA3,EFNB3,EGFR,EPHA5,EPHB1,ERBB2,ERBB4,EFEMP1,FGFR1,FGFR3,FLT1,NPTN,KIT,NTRK2,NTRK3,DDR2,PDGFRA,RET,EPHA10,TEK,TGFBR3,TIE1" GO: Molecular Function GO:0004385 guanylate kinase activity 1.32E-03 1.00E+00 3.09E-02 2.61E-01 8 14 "CASK,TJP2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3" GO: Molecular Function GO:0005251 delayed rectifier potassium channel activity 1.36E-03 1.00E+00 3.14E-02 2.66E-01 15 37 "KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNQ2,KCNQ3" GO: Molecular Function GO:0046983 protein dimerization activity 1.43E-03 1.00E+00 3.23E-02 2.73E-01 283 1317 "RALGAPA1,ABAT,ACHE,ACTN1,ACTN2,ADCY2,DSCAML1,ADCY5,ADD1,ADD2,FZD9,ADORA1,ADORA2A,ADRA1B,ADRB2,NLGN4X,NR0B1,ABCD2,AMPH,BIN1,DGKD,ALS2,APOC2,BCAS1,PDXK,ARNTL,ASCL1,ASGR1,NCOA1,DYNLL1,ATM,CADM3,MYOM1,BARD1,BCL2L2,CFLAR,DST,NAE1,MTMR2,BTRC,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SYT6,CARS,RUNX1T1,NFS1,CBLN1,CBS,KYAT1,INA,AIFM1,SCARB1,SEPT7,ZBED1,LRRFIP1,NOG,CRLF1,PLEKHB1,CHRNA4,CHRNB2,JAM2,SLIT2,SLC22A6,CLCN3,SLC24A2,ABCG2,WHRN,SUMF2,RCHY1,NECTIN3,CLOCK,ABCG1,CRYM,CSF1,TENM4,CSF1R,RIMS2,CYBB,FGFR1OP2,DAPK3,DBI,BLOC1S6,ARNT2,DLG2,DNM1,OLIG1,DRD1,PDCD6IP,DNM1L,EBF1,HEYL,RASGRP1,SH3GLB1,EGFR,TENM1,OLIG2,ENO2,GPHN,STX2,ERBB2,ERBB4,NRN1,RACK1,PRMT5,FGFR1,SYT3,SMC2,SDCBP2,GAD1,GAD2,GHR,GJB1,HPGDS,GLDC,TOX3,CBX1,GPD1,NUDT21,GRIK1,GRIK2,GRIN1,NR3C1,GRM7,GSTM5,GUCY1A1,GUCY1B1,ATOH8,IRAK3,ZHX1,ACOT7,HMGCL,HMGCR,TLX1,HP,HSF2,HSP90AA1,HES5,IL6R,IL6ST,IL12A,ITGA7,ITGAM,ITGAV,KCNB1,KCND2,KCNH1,KCNH2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KIT,LIFR,SMAD1,MAOB,MEF2C,MEIS1,MID1,MITF,CD200,GIT1,MTTP,MXI1,MYCN,MYH6,MYH7,MYO5A,MYO7A,ZNF862,NBL1,NDP,NEFH,NEUROD1,NEUROD2,NFE2L2,NHLH1,NOS1,NTRK2,OMG,P2RX7,P2RY1,PAH,PBX1,PDE2A,PDGFRA,PIK3R1,SCHIP1,PPARA,PTPA,PPP3CA,PPP3CB,MAPK4,PRPH,MASP1,PTPRE,PTPRO,QDPR,RAP1GAP,KHDRBS2,RDX,RPE,LRRK2,SYNDIG1,SOX8,KCNIP1,CLIP1,RXRA,S100B,HOGA1,SCP2,HES6,SOX6,PPP1R9A,NLGN1,ZNF365,SEPHS1,CCDC88A,SLC11A1,MTERF2,DMRTC1,SOX2,SOX5,SOX15,ZHX3,MYCBP2,ZNF423,SPTAN1,SPTB,NPAS3,LHPP,MESP1,STX1A,KLHL7,SYT11,JMJD6,SUPT5H,PLCB1,SYN1,SYN2,SYT5,MTCL1,TAF6,TAF9,TAL1,FBXW11,ANO4,TBX15,ACSL6,TCF4,TCF12,SYNE1,HIF3A,THRA,NACC2,HEY1,CBX5,BHLHB9,HEY2,TPD52,TPD52L2,NR2C2,PRMT8,PDSS1,NTSR2,ANO5,TSC2,CADM1,WRN,TRIM9,ZBTB38,ZBTB16,MAP3K12,EMSY,MFF,CADM2,PRTFDC1,HPS4,PDSS2,GOPC,FXR1" GO: Molecular Function GO:0005250 A-type (transient outward) potassium channel activity 1.45E-03 1.00E+00 3.23E-02 2.73E-01 4 4 "KCND1,KCND2,KCND3,KCNIP2" GO: Molecular Function GO:0032051 clathrin light chain binding 1.45E-03 1.00E+00 3.23E-02 2.73E-01 4 4 "CLTC,CALY,NSG2,NSG1" GO: Molecular Function GO:0004897 ciliary neurotrophic factor receptor activity 1.45E-03 1.00E+00 3.23E-02 2.73E-01 4 4 "CNTFR,IL6R,IL6ST,LIFR" GO: Molecular Function GO:0016833 oxo-acid-lyase activity 1.45E-03 1.00E+00 3.23E-02 2.73E-01 4 4 "HMGCL,HMGCLL1,HOGA1,NPL" GO: Molecular Function GO:0030551 cyclic nucleotide binding 1.54E-03 1.00E+00 3.38E-02 2.86E-01 16 41 "HCN2,CNGA3,RAPGEF4,BVES,KCNH1,HCN1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PRKAR1B,POPDC3" GO: Molecular Function GO:0047485 protein N-terminus binding 1.55E-03 1.00E+00 3.38E-02 2.86E-01 35 117 "ADCY8,NCOA1,ATM,CACNA1E,CALM1,SYNGR3,CLU,NIPBL,AKAP6,NCOR2,FEZ1,DCTN4,ERCC2,PDLIM5,GAD1,GRIN2C,RBPJ,KCNB1,KCNQ2,MYO7A,PLEC,APTX,PEX5,KCNIP2,KCNIP1,SMARCA4,SMARCE1,SNAP25,SNCA,SPTAN1,STX1A,STXBP1,ZMYND8,TSC1,PCDH15" GO: Molecular Function GO:0030234 enzyme regulator activity 1.68E-03 1.00E+00 3.65E-02 3.09E-01 224 1023 "RALGAPA1,SERPINA3,ABR,ELFN2,AXIN2,KIDINS220,AGT,TBC1D14,TAOK1,ARHGAP20,OGT,PI16,APAF1,APC,DGKZ,ALS2,APOC1,APOC2,LRRC4C,APP,PPP4R4,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,CCAR2,DYNLL1,ATP1B3,MTMR9,ADGRB3,RGS11,RGS9,CFLAR,CDK5R1,C5,CDK5R2,CALM1,KALRN,CAPN3,CAST,BRSK2,CCKBR,KRIT1,CCNH,CCNT1,RGN,ARHGEF1,DGKI,ARHGAP33,EVI5L,SOCS6,CHM,CHN1,CHN2,ARHGAP22,SLIT2,PLAA,ARHGEF6,CABP1,BAG4,NCOR1,RGS6,SIPA1L1,SOCS5,PHACTR3,CST3,PPP1R16B,GPSM1,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ZEB2,B3GAT3,TIAM2,SPOCK3,SRGAP3,SGSM2,RABGAP1L,DMPK,CPEB2,DOCK2,CASP8AP2,ABI1,RCAN1,DNAJB6,FRY,FAM13A,EGFR,RASA4,TNK2,RGS17,PCOLCE2,RCAN2,TBC1D16,TAOK3,DLC1,RACK1,STRADA,PPP1R1B,FGF13,PRKAG2,AGAP2,AGAP3,ARFGAP2,ATP6V1H,NRG3,CAB39,IQGAP2,MALT1,RUNDC3A,DBF4,PCSK1N,ADAP1,GRM7,ARHGAP19,NCKAP1L,ARHGAP36,HMGB1,AGFG1,HSP90AA1,SMAP1,IGF1,INPP5B,LRRTM3,LRRTM1,ITIH2,IPO5,STXBP5,LRRC4B,CAMK2N2,ARHGAP12,MIA2,MMP16,MMP17,GIT1,COL28A1,DBNL,MT3,MYO9A,NF1,TBC1D25,OCRL,OPHN1,PDPK1,SERPINE2,SERPINI1,PIK3R1,A2ML1,GPSM2,PLXNB1,PPP1R1A,PPP2R2B,PPP2R2C,PTPA,PPP2R5C,PPP2R5E,PKIA,PRKAR1B,MAPK8,MAPK9,PRPSAP2,BCAS3,PTN,RAB3A,RALGDS,RAP1GAP,RAP1GDS1,RGS3,RGS4,RGS7,RGS10,RGS12,RIC8B,RNH1,FBXW7,SGSM1,LRRK2,RTKN,SBF1,LRRTM4,ELMOD1,RASA3,SCG5,ITSN1,ASAP3,PREX2,RAB3GAP1,ARFGAP1,SLN,RIMS1,SNCB,SNCA,WDTC1,ARHGAP26,RAP1GAP2,LRRC4,SSPO,PLCB1,AZIN2,ARHGEF12,ARHGAP9,TIMP4,CABIN1,PIK3R5,TSC1,TSC2,HSPBP1,FLRT2,FLRT1,BCL2L13,TBC1D15,RICTOR,ELFN1,CRB2,WNK1,EVI5,GOPC,SOCS4" GO: Molecular Function GO:0005102 signaling receptor binding 1.70E-03 1.00E+00 3.65E-02 3.09E-01 338 1601 "ACTN1,ACTN2,ARID1A,ADCY6,ADD1,ADORA1,ADORA2A,ADRB2,NLGN4X,AGT,NR0B1,SEMA6A,C1QTNF4,ALCAM,LTBP4,AMH,SEMA7A,ANXA7,APLP1,DDO,APP,SEMA4G,MADD,CASK,ARNTL,ARRB1,ARRB2,CAPRIN2,PTCH2,NCOA1,RASL11B,ATP1A3,ATP2A2,ATP2B2,CADM3,RIPK1,ADAM23,ADAM15,FGF17,BID,CFLAR,BMP7,CDK5R1,DST,BTK,C5,IL33,CALM1,HAP1,CAMK2A,CANX,CAPN3,MAP7,CCK,CCKBR,CD86,CD81,CDC42,LGI1,CRLF1,CHGB,CHN1,SLIT2,NRXN3,NRXN1,NRXN2,NGEF,HOMER3,PICK1,CNTFR,AKAP5,RCHY1,NRG2,NECTIN3,CRY2,RNF14,NCOR1,NCOR2,CSF1,SIPA1L1,SOCS5,PITPNM3,CMTM5,UBXN2A,CTNND1,DOCK4,DBI,MED24,MAGI2,LYPD1,ARNT2,DLG2,DLG3,DLG4,DNM1,MED12,DNM2,SHANK1,DOCK2,CASP8AP2,DRD1,ACOT8,ATN1,PDCD6IP,ECM2,FIS1,EDIL3,EDN1,EDN3,EDNRB,FEM1B,SEMA3D,EFNA2,EFNA3,EFNB3,EBI3,EGFR,PLXNC1,IRAK4,TNK2,EPB41L1,DMTN,GPHN,ERBB2,ERBB4,PIPOX,CD320,REEP2,CACNG2,PTK2B,EFEMP1,RACK1,FCGR1A,PPP1R1B,FER,FGF1,FGF11,FGF12,FGF13,FGF14,FGR,SEMA6C,SEMA4D,TACC2,SORBS1,NPTN,CSPG5,NSG1,DLL3,NRG3,FYB1,FYN,GABRA5,GABRB1,GABRG1,TRAF3IP2,ZNF274,ERAP1,DNER,GDF1,MSTN,GDF9,GFAP,GFER,GFRA1,C1QL1,PPARGC1A,RUNDC3A,DHRS4,RND1,PCSK1N,GNAL,GNAO1,GNAS,GNG3,MCHR1,GRB10,GRIA1,GRIK3,ADAMTS13,GRIN1,ADAMTS8,NR3C1,GRM1,GRM5,PTPN5,IL1RAPL1,LINGO1,PADI2,NXPH3,NXPH2,HMGB1,GABARAPL2,HMGCL,HSP90AA1,IGF1,IGFBP1,IL6R,IL6ST,IL12A,ITGA7,ITGAV,JAK1,JAK2,KCNJ10,KIF5C,L1CAM,LAMA2,LRRC4B,LIFR,SYTL4,NCOA7,PACRG,MAG,MATK,ADAM11,IL17D,SHC3,KITLG,CD200,ADAM22,RSPO2,NDP,NODAL,NPY,NPPA,NTRK2,NUCB2,OPHN1,P2RX7,P2RY1,PALM,PDE4D,PDGFRA,PDPK1,PDYN,PENK,CYTL1,NLGN3,SERPINE2,SEMA5B,PIK3R1,PLCL1,JAKMIP1,PLXNB1,PILRA,NXPH1,MED1,PTPA,PRKCB,PROX1,RELN,BCAS3,SYTL2,LAMA1,PTCH1,PTHLH,PTK2,PTN,PTPRD,MARCH1,RASGRF1,TRIM68,MRAP2,SYNDIG1,WLS,RXRA,S100B,SEMA6D,ATXN2,SCP2,SEC14L1,NLGN4Y,SHC4,MAGI3,NLGN1,SHANK2,RTP5,ELMO2,SLIT1,SMARCA4,SMARCD3,SMARCE1,LMBRD1,USP33,DOK5,KDM3A,SPP1,KDM4C,ITPRID2,SST,SSPO,ERBIN,SYT1,TAC1,MMS19,TAC3,SEMA4A,TCF7L2,RPGRIP1L,SYNE1,NSD1,ARHGEF12,TNS2,TF,SIRT1,SPX,LEFTY2,TGFBR3,ZNF106,THBS4,TIAM1,ICAM5,TNR,IL34,DOK6,TRH,AMACR,FNDC5,CADM1,UCHL1,FLRT2,FLRT1,VAV2,VGF,WNT7A,REEP1,ANKS1B,CADM2,RGMA,SCG2,SEMA3B,PLSCR4,GOPC,MARCH8,JMJD1C,NETO2,NETO1" GO: Molecular Function GO:0042802 identical protein binding 1.91E-03 1.00E+00 4.08E-02 3.45E-01 290 1359 "ABAT,ACADM,ACHE,RBM10,ACTN1,ACTN2,DSCAML1,ADD1,ADD2,BRAP,FZD9,ADORA2A,ESYT2,ADRB2,NLGN4X,NR0B1,C1QTNF3,ALAD,ABCD2,ALK,BIN1,CDC42BPA,APAF1,APLP1,DGKD,ALS2,APOC2,BCAS1,APP,PDXK,ASCL1,ASGR1,DACT3,DYNLL1,ALDH4A1,CADM3,MYOM1,RIPK1,BARD1,BCHE,BCL2L2,HCN2,DST,BTK,MTMR2,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SYT6,CARS,RUNX1T1,NFS1,PRC1,CBLN1,CBS,CLDN10,KYAT1,USP2,P2RX6,SCARB1,ENTPD2,SEPT7,CDC42,LRRFIP1,NOG,PLEKHB1,SLIT2,SLC22A6,CLCN3,ABCG2,PICK1,WHRN,SUMF2,RCHY1,NECTIN3,C1QL2,ABCG1,CRYM,SNCAIP,CSF1,TENM4,CSF1R,CST3,APPL1,FGFR1OP2,ACY3,DAPK1,DAPK3,DCC,BLOC1S6,GRIN3A,DNM1,SHANK1,CASP8AP2,PDCD6IP,RCAN1,DYRK1A,DNM1L,ABCC9,ATL1,PHC2,HEYL,RASGRP1,OPTN,SH3GLB1,EGFR,TENM1,TNK2,OLIG2,ENO2,GPHN,ERBB2,ERBB4,NRN1,RACK1,FGFR1,BAIAP2,AMOTL2,FLT1,SYT3,SDCBP2,MSTN,ARFIP1,GHR,GJB1,HPGDS,GLDC,TOX3,GLUL,CBX1,GP1BB,GPD1,NUDT21,GRIA1,GRIA2,C1QL4,GRIK1,GRIK2,GRIK5,NR3C1,GRM1,GRM7,GSTM5,IRAK3,PACSIN2,ACOT7,HMGCL,HMGCR,HP,HSF2,HSP90AA1,IFI16,IL6R,IL6ST,KCNH1,KCNH2,KCNJ10,KCNK3,KCNMA1,KCNN2,KIT,L1CAM,SMAD1,PIK3AP1,MAOB,SYT9,MID1,CD200,GIT1,MYH6,MYH7,MYO7A,NBL1,NCAM1,NDP,NELL1,NELL2,VWA2,NOS1,NPR2,HCN1,NTRK2,OMG,CLDN11,P2RX7,PAH,PDE2A,PDGFRA,GPSM2,SCHIP1,POU3F2,PTPA,PPP5C,PRKAB2,MAPK4,MASP1,UHRF1BP1,PTK2,PTPRE,CASTOR1,PTPRG,PTPRO,QDPR,RAD52,ATG16L1,RAP1GAP,RDX,KCTD17,ROBO1,ROBO2,MRAP2,RPE,FBXW7,LRRK2,SYNDIG1,KCNIP2,CLIP1,S100B,ATXN1,HOGA1,SCP2,HES6,CASC3,PUF60,PPP1R9A,SH3GL2,SH3GL3,SHMT2,CNKSR2,ZNF365,SEPHS1,CCDC88A,SLC11A1,MTERF2,DMRTC1,SNCA,SOX10,FNBP1,ZHX3,MYCBP2,ZNF423,LHPP,STXBP1,KLHL7,SYT11,JMJD6,PLCB1,SYP,SYT1,MTCL1,CNTN2,TBX15,ACSL6,TCF4,TPCN2,TCF12,SYNE1,RALYL,SIRT1,THRA,NACC2,HEY1,CBX5,BHLHB9,HEY2,TP53BP2,TPD52,TPD52L2,RGMB,PRMT8,NTSR2,TSC2,CADM1,PLEKHH2,WRN,ETNPPL,SF1,TRIM9,ZBTB38,ZBTB16,MAP3K12,EMSY,MFF,CADM2,PRTFDC1,HPS4,GOPC,FXR1" GO: Molecular Function GO:0003777 microtubule motor activity 2.03E-03 1.00E+00 4.23E-02 3.58E-01 25 77 "KIF6,DNAH17,KIF1A,KIF26A,KIF19,DNAH9,DYNC1I1,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,DNHD1,KIF7,KIF27,KIF21A,KIF16B,KIF13A,KIF21B,KIF1B,DNAH7,KLC2,DNALI1,DNAH10" GO: Molecular Function GO:0048365 Rac GTPase binding 2.06E-03 1.00E+00 4.23E-02 3.58E-01 16 42 "HACE1,ALS2,WASF1,ARHGEF2,DOCK4,SRGAP3,ABI2,MTSS1L,EPS8,NCKAP1,IQGAP2,DOCK7,ITPKA,NCF2,OCRL,TIAM1" GO: Molecular Function GO:0008373 sialyltransferase activity 2.06E-03 1.00E+00 4.23E-02 3.58E-01 10 21 "ST3GAL5,ST8SIA3,ST3GAL6,ST6GALNAC3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" GO: Molecular Function GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential 2.06E-03 1.00E+00 4.23E-02 3.58E-01 10 21 "ASIC2,HCN2,HCN1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCN3B" GO: Molecular Function GO:0005248 voltage-gated sodium channel activity 2.06E-03 1.00E+00 4.23E-02 3.58E-01 10 21 "ASIC2,HCN2,HCN1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCN3B" GO: Molecular Function GO:0015103 inorganic anion transmembrane transporter activity 2.16E-03 1.00E+00 4.39E-02 3.72E-01 38 132 "TTYH1,SLC12A5,AQP6,SLC4A4,SLC22A6,CLCN3,CLCN4,SLC4A7,SLC4A8,SLC12A6,PCYOX1,SLC37A3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,ADAMTS8,TTYH2,BEST3,FXYD1,SLC26A11,SLC4A3,SLC12A2,SLC12A4,SLC20A2,SLC37A2,ANO4,ANO5,BEST1,SLC26A10,SLC17A7,SLC4A10" GO: Molecular Function GO:0008081 phosphoric diester hydrolase activity 2.19E-03 1.00E+00 4.42E-02 3.74E-01 30 98 "ADORA1,PDE8B,CCKBR,CHRM1,PLCH2,PLCXD3,EDNRA,ENPP6,GNAS,PLCD4,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PLCB2,PLCD1,PLCL1,GDPD1,GDPD2,SMPD3,PLCB1,GDPD5,MPPE1,PLD4" GO: Molecular Function GO:0015269 calcium-activated potassium channel activity 2.27E-03 1.00E+00 4.52E-02 3.82E-01 9 18 "KCNT1,KCNMB2,KCNMB4,KCNMA1,KCNN1,KCNN2,KCNN3,TMEM38A,KCNT2" GO: Molecular Function GO:0031701 angiotensin receptor binding 2.31E-03 1.00E+00 4.52E-02 3.82E-01 7 12 "AGT,ARRB1,ARRB2,DRD1,EDNRB,GNG3,JAK2" GO: Molecular Function GO:0015271 outward rectifier potassium channel activity 2.31E-03 1.00E+00 4.52E-02 3.82E-01 7 12 "KCNA2,KCNB1,KCND1,KCND2,KCND3,KCNK2,KCNIP2" GO: Molecular Function GO:0005283 amino acid:sodium symporter activity 2.31E-03 1.00E+00 4.52E-02 3.82E-01 7 12 "SLC6A15,SLC1A2,SLC6A1,SLC6A7,SLC6A9,SLC6A11,SLC38A1" GO: Molecular Function GO:0042043 neurexin family protein binding 2.38E-03 1.00E+00 4.62E-02 3.91E-01 8 15 "NLGN4X,CASK,DLG4,SYTL4,NLGN3,SYTL2,NLGN4Y,NLGN1" GO: Molecular Function GO:1902936 phosphatidylinositol bisphosphate binding 2.44E-03 1.00E+00 4.70E-02 3.98E-01 26 82 "ACTN2,AMER3,CADPS,KRIT1,FRMPD4,PLEKHA1,MTSS1L,CLVS1,WASHC2A,SCIN,CLVS2,MARK1,HCN1,PIRT,PLCD1,MAPKAP1,SYTL2,AMER2,KIF16B,RPH3A,PLCB1,SYT1,ATP13A2,PARD3,TTPA,SNX14" GO: Molecular Function GO:0032947 protein-containing complex scaffold activity 2.48E-03 1.00E+00 4.75E-02 4.02E-01 25 78 "ARRB2,HCN2,KSR1,CAPN3,SPAG9,MAGI1,DLGAP3,AKAP7,AKAP6,AKAP12,MAGI2,G3BP2,SHANK1,GPHN,RACK1,DISC1,TNRC6A,KSR2,LRRK2,ITSN1,MAGI3,SHANK2,MAPK8IP3,MMS19,WWC1" GO: Molecular Function GO:0004713 protein tyrosine kinase activity 2.62E-03 1.00E+00 4.99E-02 4.23E-01 49 182 "CLK4,ALK,FGF17,NRP2,BTK,DDR1,NRG2,AATK,CSF1R,CSF2RA,FGFR1OP2,DYRK1A,EDNRA,EFNA3,EFNB3,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,EFEMP1,TESK2,FER,FGF1,FGFR1,FGFR3,FGR,FLT1,NPTN,CAMKK2,FYN,CNTRL,HSP90AA1,JAK1,JAK2,KIT,MATK,NEK1,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1" GO: Biological Process GO:0099536 synaptic signaling 1.18E-63 1.16E-59 4.22E-60 4.12E-59 315 687 "ABAT,SYN3,ASIC2,ASIC1,ACHE,ABHD6,SLC12A5,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,AGT,PLA2G6,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,PPFIA2,CNIH2,PPFIA1,APBA2,ALS2,PPFIA3,CASK,ARRB2,CADPS,ATP1A2,ATP2A2,ATP2B2,BCHE,CDK5R1,SYNJ1,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,SYT6,CBLN1,SHISA7,CCKBR,CD38,NEURL1,DGKI,CDH8,LGI1,DLGAP2,DLGAP1,CACNA2D2,CHRM1,CHRM4,CHRNA4,CHRNB2,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,CNR1,PICK1,AKAP5,PNKD,CRHBP,SLC32A1,SNCAIP,SIPA1L1,RIMS4,SLITRK5,CTNND2,RIMS2,CX3CR1,SNPH,RIMS3,DAPK1,DBI,DBN1,CNIH3,BLOC1S6,LYPD1,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,DNM1,DMPK,SHANK1,SLC12A6,DRD1,DTNA,EDN1,EDN3,SYT15,CACNG7,EGFR,EGR3,SEZ6,KCNMB2,STX2,ERBB4,RTN3,CACNG3,CACNG2,PTK2B,FGF12,FGF14,BAIAP2,SYT3,NPTN,CSPG5,STAU2,BRSK1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,GAD1,GAD2,JPH4,SYT17,CPLX2,CPLX1,GFAP,PCDH17,PPARGC1A,GLRB,GLS,GLUL,KCNMB4,GPM6B,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,PTGDR2,HRH3,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNA1,KCNB1,KCND2,KCNJ10,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,NAT8L,MAPT,MBP,SYT9,SHC3,MEF2C,MYO5A,MYO6,NCAM1,NEUROD2,NF1,NOS1,NPY,NOVA1,NPTX1,NPTX2,NRGN,NTRK2,OPHN1,OPRL1,OXTR,P2RX7,PCDH8,PDYN,PENK,TMOD2,NLGN3,SERPINE2,PLCL1,PLP1,PMP22,PPP3CA,PPP3CB,PRKCG,PRKCZ,RELN,SYTL2,PTK2,PXK,PTN,PTPRD,PTPRN2,RAB3A,RASGRF1,RASGRF2,RGS10,RIT2,LRRK2,KCNIP2,STX1B,S100B,ATXN1,LRFN5,SCN2B,NLGN4Y,PPP1R9A,CPEB3,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLC12A4,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,KIF1B,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,NCDN,STAU1,STX1A,STXBP1,SYT11,PLCB1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,TAC1,TACR1,CNTN2,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,TNR,RASD2,ZMYND8,VGF,WNT7A,TRIM9,CELF4,LRP8,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0098916 anterograde trans-synaptic signaling 1.72E-63 1.69E-59 4.22E-60 4.12E-59 312 678 "ABAT,SYN3,ASIC2,ASIC1,ACHE,ABHD6,SLC12A5,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,AGT,PLA2G6,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,PPFIA2,CNIH2,PPFIA1,APBA2,ALS2,PPFIA3,CASK,ARRB2,CADPS,ATP1A2,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,SYT6,CBLN1,SHISA7,CCKBR,CD38,NEURL1,DGKI,CDH8,LGI1,DLGAP2,DLGAP1,CACNA2D2,CHRM1,CHRM4,CHRNA4,CHRNB2,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,CNR1,PICK1,AKAP5,PNKD,CRHBP,SLC32A1,SNCAIP,SIPA1L1,RIMS4,SLITRK5,CTNND2,RIMS2,CX3CR1,SNPH,RIMS3,DAPK1,DBI,DBN1,CNIH3,BLOC1S6,LYPD1,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,DNM1,DMPK,SHANK1,SLC12A6,DRD1,DTNA,EDN1,EDN3,SYT15,CACNG7,EGFR,EGR3,SEZ6,KCNMB2,STX2,ERBB4,RTN3,CACNG3,CACNG2,PTK2B,FGF12,FGF14,BAIAP2,SYT3,NPTN,CSPG5,STAU2,BRSK1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,GAD1,GAD2,JPH4,SYT17,CPLX2,CPLX1,GFAP,PCDH17,PPARGC1A,GLRB,GLS,GLUL,KCNMB4,GPM6B,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,PTGDR2,HRH3,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNA1,KCNB1,KCND2,KCNJ10,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,NAT8L,MAPT,MBP,SYT9,SHC3,MEF2C,MYO5A,MYO6,NCAM1,NEUROD2,NF1,NOS1,NPY,NOVA1,NPTX1,NPTX2,NRGN,NTRK2,OPHN1,OPRL1,OXTR,P2RX7,PCDH8,PDYN,PENK,TMOD2,NLGN3,SERPINE2,PLCL1,PLP1,PMP22,PPP3CA,PPP3CB,PRKCG,PRKCZ,RELN,SYTL2,PTK2,PXK,PTN,PTPRD,PTPRN2,RAB3A,RASGRF1,RASGRF2,RIT2,LRRK2,KCNIP2,STX1B,S100B,ATXN1,LRFN5,SCN2B,NLGN4Y,PPP1R9A,CPEB3,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLC12A4,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,KIF1B,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,NCDN,STAU1,STX1A,STXBP1,SYT11,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,TAC1,TACR1,CNTN2,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,TNR,RASD2,ZMYND8,VGF,WNT7A,TRIM9,CELF4,LRP8,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0099537 trans-synaptic signaling 1.72E-63 1.69E-59 4.22E-60 4.12E-59 312 678 "ABAT,SYN3,ASIC2,ASIC1,ACHE,ABHD6,SLC12A5,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,AGT,PLA2G6,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,PPFIA2,CNIH2,PPFIA1,APBA2,ALS2,PPFIA3,CASK,ARRB2,CADPS,ATP1A2,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,SYT6,CBLN1,SHISA7,CCKBR,CD38,NEURL1,DGKI,CDH8,LGI1,DLGAP2,DLGAP1,CACNA2D2,CHRM1,CHRM4,CHRNA4,CHRNB2,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,CNR1,PICK1,AKAP5,PNKD,CRHBP,SLC32A1,SNCAIP,SIPA1L1,RIMS4,SLITRK5,CTNND2,RIMS2,CX3CR1,SNPH,RIMS3,DAPK1,DBI,DBN1,CNIH3,BLOC1S6,LYPD1,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,DNM1,DMPK,SHANK1,SLC12A6,DRD1,DTNA,EDN1,EDN3,SYT15,CACNG7,EGFR,EGR3,SEZ6,KCNMB2,STX2,ERBB4,RTN3,CACNG3,CACNG2,PTK2B,FGF12,FGF14,BAIAP2,SYT3,NPTN,CSPG5,STAU2,BRSK1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,GAD1,GAD2,JPH4,SYT17,CPLX2,CPLX1,GFAP,PCDH17,PPARGC1A,GLRB,GLS,GLUL,KCNMB4,GPM6B,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,PTGDR2,HRH3,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNA1,KCNB1,KCND2,KCNJ10,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,NAT8L,MAPT,MBP,SYT9,SHC3,MEF2C,MYO5A,MYO6,NCAM1,NEUROD2,NF1,NOS1,NPY,NOVA1,NPTX1,NPTX2,NRGN,NTRK2,OPHN1,OPRL1,OXTR,P2RX7,PCDH8,PDYN,PENK,TMOD2,NLGN3,SERPINE2,PLCL1,PLP1,PMP22,PPP3CA,PPP3CB,PRKCG,PRKCZ,RELN,SYTL2,PTK2,PXK,PTN,PTPRD,PTPRN2,RAB3A,RASGRF1,RASGRF2,RIT2,LRRK2,KCNIP2,STX1B,S100B,ATXN1,LRFN5,SCN2B,NLGN4Y,PPP1R9A,CPEB3,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLC12A4,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,KIF1B,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,NCDN,STAU1,STX1A,STXBP1,SYT11,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,TAC1,TACR1,CNTN2,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,TNR,RASD2,ZMYND8,VGF,WNT7A,TRIM9,CELF4,LRP8,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0007268 chemical synaptic transmission 1.72E-63 1.69E-59 4.22E-60 4.12E-59 312 678 "ABAT,SYN3,ASIC2,ASIC1,ACHE,ABHD6,SLC12A5,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,AGT,PLA2G6,SYT13,DOC2A,AMPH,LRFN1,PPFIA4,PPFIA2,CNIH2,PPFIA1,APBA2,ALS2,PPFIA3,CASK,ARRB2,CADPS,ATP1A2,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,SYT6,CBLN1,SHISA7,CCKBR,CD38,NEURL1,DGKI,CDH8,LGI1,DLGAP2,DLGAP1,CACNA2D2,CHRM1,CHRM4,CHRNA4,CHRNB2,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,CNR1,PICK1,AKAP5,PNKD,CRHBP,SLC32A1,SNCAIP,SIPA1L1,RIMS4,SLITRK5,CTNND2,RIMS2,CX3CR1,SNPH,RIMS3,DAPK1,DBI,DBN1,CNIH3,BLOC1S6,LYPD1,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,DNM1,DMPK,SHANK1,SLC12A6,DRD1,DTNA,EDN1,EDN3,SYT15,CACNG7,EGFR,EGR3,SEZ6,KCNMB2,STX2,ERBB4,RTN3,CACNG3,CACNG2,PTK2B,FGF12,FGF14,BAIAP2,SYT3,NPTN,CSPG5,STAU2,BRSK1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,GAD1,GAD2,JPH4,SYT17,CPLX2,CPLX1,GFAP,PCDH17,PPARGC1A,GLRB,GLS,GLUL,KCNMB4,GPM6B,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,PTGDR2,HRH3,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,KCNA1,KCNB1,KCND2,KCNJ10,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,NAT8L,MAPT,MBP,SYT9,SHC3,MEF2C,MYO5A,MYO6,NCAM1,NEUROD2,NF1,NOS1,NPY,NOVA1,NPTX1,NPTX2,NRGN,NTRK2,OPHN1,OPRL1,OXTR,P2RX7,PCDH8,PDYN,PENK,TMOD2,NLGN3,SERPINE2,PLCL1,PLP1,PMP22,PPP3CA,PPP3CB,PRKCG,PRKCZ,RELN,SYTL2,PTK2,PXK,PTN,PTPRD,PTPRN2,RAB3A,RASGRF1,RASGRF2,RIT2,LRRK2,KCNIP2,STX1B,S100B,ATXN1,LRFN5,SCN2B,NLGN4Y,PPP1R9A,CPEB3,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLC12A4,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,KIF1B,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,NCDN,STAU1,STX1A,STXBP1,SYT11,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,TAC1,TACR1,CNTN2,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,NR2E1,TNR,RASD2,ZMYND8,VGF,WNT7A,TRIM9,CELF4,LRP8,SLC17A7,NETO2,NETO1,JPH3" GO: Biological Process GO:0022008 neurogenesis 2.10E-59 2.06E-55 4.12E-56 4.02E-55 561 1628 "ACHE,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,FZD9,ADORA2A,UNC5A,LRFN2,KIDINS220,BEND6,NLGN4X,AGT,DISP3,LRRC7,SEMA6A,ALCAM,ALK,MRTFA,BIN1,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,PRX,SPTBN4,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,ASTN1,ATP2B2,ADGRB1,ADGRB3,BCHE,NRP2,PROM1,BMP7,BMPR1B,CDK5R1,SYNJ1,ARHGEF7,MTMR2,GPC2,RAB29,MYRF,CDK5R2,IL33,MMD2,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,SPAG9,CBLN1,CCK,AIFM1,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,SEPT7,CDC42,CDH2,DCLK1,LGI1,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,SLC4A7,ZNF521,CRMP1,AATK,CSF1,TENM4,CSF1R,RGS6,FEZ2,FEZ1,ARHGEF10,CSNK1E,SIPA1L1,CHD5,VCAN,CNTNAP2,PLXNA4,SLITRK5,CTNND2,RIMS2,CX3CR1,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBI,DBN1,DCC,DCT,ZEB2,MYEF2,KIAA0319,MAGI2,BLOC1S6,GSDME,PLPPR4,SNAP91,NTM,CHRDL1,DLG2,DLG4,DLX1,GRIN3A,DMD,OLIG1,NYAP1,MED12,TRAPPC9,CDON,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DSCAM,ECM2,USH1C,WDPCP,EDN3,EDNRB,ATL1,HEYL,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G1,EIF4G2,ELAVL4,EML1,EMX2,EN2,OLIG2,COQ7,SEZ6,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,CEND1,ADGRV1,EYA1,NRN1,FABP7,ACSL4,PTK2B,TUBB3,EFEMP1,FKTN,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,FOXO3,EVL,SEMA4D,SYT3,DPYSL4,TACC2,PDLIM5,USP21,NPTN,DLL3,STAU2,TBR1,NRG3,BRSK1,FYN,GABRA5,CHL1,GABRB1,GABRB3,NKX6-2,SALL3,GAP43,SYT17,DISC1,ATP8A2,WASF3,DNER,GBX2,GFAP,GFRA1,C1QL1,KIRREL3,NTNG2,RND1,GLI2,DCLK2,GNAO1,GPM6A,GPER1,CECR2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,GSN,KIF3A,RNF165,PTPN5,IL1RAPL1,SOX21,LINGO1,HMGB1,HNRNPK,TLX1,NEGR1,HSP90AA1,ATCAY,IGF1,NKD1,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SCRT2,BRINP3,INSM1,TUBB2B,ITGAM,ITPKA,JAK2,KCNA1,OLFM3,KCNJ10,KCNMA1,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIG4,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MARK1,MATN2,MBD1,MBP,MEF2C,MEIS1,AFDN,CPNE9,GIT1,DBNL,BLOC1S2,ADAM22,NRBP2,MT3,MTR,RSPO2,MDGA1,MYCN,MYO6,MYO7A,NAP1L2,NBL1,NCAM1,NEFM,NEFH,NEUROD1,NEUROD2,NF1,NFE2L2,NFIX,NKX2-2,NNAT,NOS1,NPY,NPTX1,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,OGDH,OMG,OPA1,OPCML,OPHN1,P2RY1,PAK3,PALM,PAX6,PBX1,ENPP2,GPR173,PENK,NLGN3,SERPINE2,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,SDK2,MBOAT7,PACSIN1,FA2H,FAT3,POU3F2,POU3F4,MED1,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,MAPK9,PROX1,RELN,KLK6,PSD,LAMA1,MDGA2,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,STRC,RAB3A,SH3TC2,FAT4,RAP1GAP,ROGDI,RASGRF1,FEZF2,CRTAC1,RET,ROBO1,ROBO2,ROM1,RORB,RPE65,GLDN,LRRK2,SOX8,ATAT1,KCNIP2,RTN1,RXRA,S100B,SALL1,SEMA6D,ATXN1,DRAXIN,ATXN2,LRFN5,SOX6,SGK1,PPP1R9A,ARX,CPEB3,NTNG1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,SLC8A3,SIRT2,CDK5RAP3,CCDC88A,TRIM67,EFHD1,SLIT1,SMARCA4,SMARCC2,CDK5RAP2,SMARCD3,SMARCE1,RIMS1,SNAP25,FAIM2,PALLD,MYO16,USP33,SOX1,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,MESP1,EPB41L3,ZC4H2,NCDN,MAPK8IP3,KANK1,STXBP1,SYT1,COBL,SYT4,TACC1,SEMA4A,ROBO3,TAL1,CAMSAP2,UNC5D,CNTN2,ADGRL3,AGTPBP1,ACSL6,VWC2,TCF4,SATB2,CUX2,TCF7L2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,TF,DICER1,SIRT1,CRB1,HHIP,THBS4,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,HEY2,PARD3,TNR,RBFOX2,ZMYND8,LRTM2,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,MTCH1,VLDLR,P2RY12,WNT7A,XRCC4,LGI4,ZIC2,NDRG4,DPYSL5,PLPPR5,WNK1,LRP8,RGMA,GDPD5,STMN4,PRDM8,SEMA3B,PCDH15,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,IFT88,SLC4A10" GO: Biological Process GO:0048699 generation of neurons 6.32E-57 6.20E-53 1.03E-53 1.01E-52 530 1528 "ACHE,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,FZD9,ADORA2A,UNC5A,LRFN2,KIDINS220,BEND6,NLGN4X,DISP3,LRRC7,SEMA6A,ALCAM,ALK,MRTFA,BIN1,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,ASTN1,ATP2B2,ADGRB1,ADGRB3,BCHE,NRP2,PROM1,BMP7,BMPR1B,CDK5R1,SYNJ1,MTMR2,GPC2,RAB29,CDK5R2,MMD2,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,SPAG9,CBLN1,CCK,AIFM1,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,SEPT7,CDC42,CDH2,DCLK1,LGI1,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,SLC4A7,ZNF521,CRMP1,AATK,CSF1,TENM4,CSF1R,RGS6,FEZ2,FEZ1,CSNK1E,SIPA1L1,CHD5,CNTNAP2,PLXNA4,SLITRK5,CTNND2,RIMS2,CX3CR1,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBN1,DCC,DCT,ZEB2,MYEF2,KIAA0319,MAGI2,BLOC1S6,GSDME,PLPPR4,SNAP91,NTM,CHRDL1,DLG2,DLG4,DLX1,GRIN3A,DMD,OLIG1,NYAP1,TRAPPC9,CDON,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DSCAM,ECM2,USH1C,WDPCP,EDN3,EDNRB,ATL1,HEYL,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G1,EIF4G2,ELAVL4,EML1,EMX2,EN2,OLIG2,SEZ6,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,CEND1,ADGRV1,EYA1,NRN1,ACSL4,PTK2B,TUBB3,EFEMP1,FKTN,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,FOXO3,EVL,SEMA4D,SYT3,DPYSL4,PDLIM5,USP21,NPTN,DLL3,STAU2,TBR1,NRG3,BRSK1,FYN,GABRA5,CHL1,GABRB1,GABRB3,NKX6-2,SALL3,GAP43,SYT17,DISC1,ATP8A2,DNER,GBX2,GFAP,GFRA1,C1QL1,KIRREL3,NTNG2,RND1,GLI2,DCLK2,GNAO1,GPM6A,GPER1,CECR2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,KIF3A,RNF165,PTPN5,IL1RAPL1,SOX21,LINGO1,HMGB1,HNRNPK,TLX1,NEGR1,HSP90AA1,ATCAY,NKD1,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SCRT2,BRINP3,INSM1,TUBB2B,ITPKA,JAK2,KCNA1,OLFM3,KCNMA1,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIG4,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MARK1,MATN2,MBD1,MBP,MEF2C,MEIS1,AFDN,CPNE9,GIT1,DBNL,BLOC1S2,NRBP2,MT3,MTR,RSPO2,MDGA1,MYCN,MYO6,MYO7A,NAP1L2,NBL1,NCAM1,NEFM,NEFH,NEUROD1,NEUROD2,NF1,NFE2L2,NFIX,NKX2-2,NNAT,NOS1,NPY,NPTX1,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,OGDH,OMG,OPA1,OPCML,OPHN1,PAK3,PALM,PAX6,PBX1,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,SDK2,PACSIN1,FAT3,POU3F2,POU3F4,MED1,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,MAPK9,PROX1,RELN,KLK6,PSD,LAMA1,MDGA2,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,STRC,RAB3A,FAT4,RAP1GAP,RASGRF1,FEZF2,CRTAC1,RET,ROBO1,ROBO2,ROM1,RORB,RPE65,GLDN,LRRK2,SOX8,ATAT1,KCNIP2,RTN1,RXRA,S100B,SALL1,SEMA6D,ATXN1,DRAXIN,ATXN2,LRFN5,SGK1,PPP1R9A,ARX,CPEB3,NTNG1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,SIRT2,CDK5RAP3,CCDC88A,TRIM67,EFHD1,SLIT1,SMARCC2,CDK5RAP2,SMARCD3,RIMS1,SNAP25,FAIM2,PALLD,MYO16,USP33,SOX1,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,EPB41L3,ZC4H2,NCDN,MAPK8IP3,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,TAL1,CAMSAP2,UNC5D,CNTN2,ADGRL3,AGTPBP1,ACSL6,VWC2,TCF4,SATB2,CUX2,TCF7L2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,TF,DICER1,SIRT1,CRB1,HHIP,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,PARD3,TNR,RBFOX2,ZMYND8,LRTM2,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,MTCH1,VLDLR,P2RY12,WNT7A,XRCC4,LGI4,ZIC2,NDRG4,DPYSL5,PLPPR5,WNK1,LRP8,RGMA,GDPD5,STMN4,PRDM8,SEMA3B,PCDH15,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,IFT88,SLC4A10" GO: Biological Process GO:0030182 neuron differentiation 3.07E-52 3.01E-48 4.31E-49 4.21E-48 486 1398 "ACHE,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,ADORA2A,UNC5A,LRFN2,KIDINS220,BEND6,NLGN4X,DISP3,LRRC7,SEMA6A,ALCAM,ALK,MRTFA,BIN1,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,ASCL1,CAPRIN2,BRINP2,NCOA1,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,PROM1,BMP7,BMPR1B,CDK5R1,MTMR2,GPC2,RAB29,MMD2,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,SPAG9,CBLN1,CCK,AIFM1,ARHGEF1,CBFA2T2,NEURL1,SEPT7,CDC42,CDH2,DCLK1,LGI1,NOG,NUMBL,GPR37L1,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,SLC4A7,ZNF521,CRMP1,AATK,TENM4,CSF1R,RGS6,FEZ2,FEZ1,CSNK1E,SIPA1L1,CHD5,CNTNAP2,PLXNA4,SLITRK5,CTNND2,RIMS2,BOC,HDAC9,SNPH,KIF26A,IST1,DGKG,DAPK3,BRINP1,DBN1,DCC,ZEB2,MYEF2,KIAA0319,MAGI2,BLOC1S6,GSDME,PLPPR4,SNAP91,NTM,CHRDL1,DLG2,DLG4,DLX1,GRIN3A,DMD,OLIG1,NYAP1,TRAPPC9,CDON,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DSCAM,ECM2,USH1C,WDPCP,EDN3,EDNRB,ATL1,HEYL,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G1,EIF4G2,ELAVL4,EMX2,EN2,OLIG2,SEZ6,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,ETV1,CEND1,ADGRV1,EYA1,NRN1,ACSL4,PTK2B,TUBB3,EFEMP1,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,FOXO3,EVL,SEMA4D,SYT3,DPYSL4,PDLIM5,USP21,NPTN,STAU2,TBR1,BRSK1,FYN,GABRA5,CHL1,GABRB1,GABRB3,NKX6-2,SALL3,GAP43,SYT17,DISC1,ATP8A2,GBX2,GFAP,GFRA1,C1QL1,KIRREL3,NTNG2,RND1,GLI2,DCLK2,GNAO1,GPM6A,CECR2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,KIF3A,RNF165,PTPN5,IL1RAPL1,SOX21,LINGO1,HMGB1,HNRNPK,TLX1,NEGR1,ATCAY,NKD1,RBPJ,DOCK7,KNDC1,HES5,BRINP3,INSM1,ITPKA,JAK2,OLFM3,KCNMA1,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBD1,MBP,MEF2C,MEIS1,CPNE9,GIT1,DBNL,BLOC1S2,NRBP2,MT3,MTR,RSPO2,MDGA1,MYCN,MYO6,MYO7A,NAP1L2,NBL1,NCAM1,NEFM,NEFH,NEUROD1,NEUROD2,NF1,NFE2L2,NFIX,NKX2-2,NNAT,NPY,NPTX1,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,OGDH,OMG,OPA1,OPCML,OPHN1,PAK3,PALM,PAX6,PBX1,NLGN3,SERPINE2,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,SDK2,PACSIN1,FAT3,POU3F2,POU3F4,MED1,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,MAPK9,PROX1,RELN,KLK6,PSD,LAMA1,MDGA2,PTCH1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,PEX5,STRC,RAB3A,FAT4,RAP1GAP,RASGRF1,FEZF2,CRTAC1,RET,ROBO1,ROBO2,ROM1,RORB,RPE65,GLDN,LRRK2,SOX8,ATAT1,KCNIP2,RTN1,RXRA,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,LRFN5,SGK1,PPP1R9A,ARX,CPEB3,NTNG1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,CDK5RAP3,CCDC88A,TRIM67,EFHD1,SLIT1,SMARCC2,CDK5RAP2,RIMS1,SNAP25,FAIM2,PALLD,MYO16,USP33,SOX1,SOX2,SOX3,TNIK,SOX5,SOX11,MYCBP2,SPP1,KDM4C,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,EPB41L3,ZC4H2,NCDN,MAPK8IP3,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,TAL1,CAMSAP2,UNC5D,CNTN2,AGTPBP1,ACSL6,VWC2,TCF4,SATB2,CUX2,ZEB1,TCF12,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,CRB1,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,PARD3,TNR,RBFOX2,ZMYND8,LRTM2,TTC3,EIF4ENIF1,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,MTCH1,VLDLR,WNT7A,LGI4,ZIC2,NDRG4,DPYSL5,PLPPR5,WNK1,LRP8,RGMA,GDPD5,STMN4,PRDM8,SEMA3B,PCDH15,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,IFT88,SLC4A10" GO: Biological Process GO:0048666 neuron development 2.89E-45 2.84E-41 3.55E-42 3.46E-41 397 1114 "ACHE,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,ADORA2A,UNC5A,LRFN2,KIDINS220,LRRC7,SEMA6A,ALCAM,ALK,MRTFA,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,ASCL1,CAPRIN2,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CDK5R1,MTMR2,RAB29,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,CBFA2T2,NEURL1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CNGA3,CNR1,PICK1,CNTN1,WHRN,AKAP5,SLC4A7,CRMP1,AATK,TENM4,CSF1R,FEZ2,FEZ1,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,CTNND2,RIMS2,BOC,KIF26A,IST1,DGKG,DBN1,DCC,ZEB2,KIAA0319,MAGI2,BLOC1S6,PLPPR4,SNAP91,NTM,DLG2,DLG4,GRIN3A,DMD,NYAP1,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DSCAM,ECM2,USH1C,WDPCP,EDNRB,ATL1,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G2,ELAVL4,EN2,SEZ6,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,ADGRV1,NRN1,ACSL4,PTK2B,TUBB3,EFEMP1,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,PDLIM5,USP21,NPTN,STAU2,TBR1,BRSK1,FYN,GABRA5,CHL1,GABRB1,GABRB3,SALL3,GAP43,SYT17,DISC1,ATP8A2,GBX2,GFAP,GFRA1,C1QL1,KIRREL3,NTNG2,RND1,GLI2,DCLK2,GNAO1,GPM6A,CECR2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,KIF3A,RNF165,PTPN5,IL1RAPL1,LINGO1,HMGB1,HNRNPK,NEGR1,ATCAY,RBPJ,DOCK7,KNDC1,HES5,INSM1,ITPKA,JAK2,OLFM3,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,CPNE9,GIT1,DBNL,BLOC1S2,MT3,MTR,MYO6,MYO7A,NBL1,NCAM1,NEFM,NEFH,NEUROD1,NEUROD2,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,OGDH,OMG,OPA1,OPCML,OPHN1,PAK3,PALM,PAX6,NLGN3,SERPINE2,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,MAPK9,RELN,KLK6,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,STRC,RAB3A,FAT4,RASGRF1,FEZF2,CRTAC1,RET,ROBO1,ROBO2,RORB,RPE65,GLDN,LRRK2,ATAT1,KCNIP2,RXRA,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,SGK1,PPP1R9A,ARX,CPEB3,NTNG1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,CCDC88A,TRIM67,EFHD1,SLIT1,RIMS1,SNAP25,PALLD,MYO16,USP33,SOX1,SOX3,TNIK,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,EPB41L3,NCDN,MAPK8IP3,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,ACSL6,CUX2,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,CRB1,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,ZMYND8,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,MTCH1,VLDLR,WNT7A,LGI4,ZIC2,NDRG4,DPYSL5,PLPPR5,WNK1,LRP8,RGMA,GDPD5,STMN4,PRDM8,SEMA3B,PCDH15,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,IFT88,SLC4A10" GO: Biological Process GO:0050804 modulation of chemical synaptic transmission 1.58E-43 1.55E-39 1.73E-40 1.69E-39 180 357 "ABAT,SYN3,ASIC1,ACHE,ABHD6,ADORA1,ADORA2A,NLGN4X,AGT,PLA2G6,CNIH2,PPFIA3,ARRB2,ATP1A2,ATP2A2,ATP2B2,BCHE,SYNJ1,MTMR2,CACNA1A,CACNA1B,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,SHISA7,CCKBR,CD38,NEURL1,DGKI,LGI1,CACNA2D2,CHRNA4,CHRNB2,NRXN1,SLC24A2,CNR1,PICK1,PNKD,CRHBP,SNCAIP,SIPA1L1,RIMS4,CTNND2,RIMS2,CX3CR1,RIMS3,DAPK1,DBI,DBN1,CNIH3,DLG4,DNM1,DMPK,SHANK1,DRD1,EDN1,EDN3,CACNG7,EGFR,ERBB4,CACNG3,CACNG2,PTK2B,FGF14,BAIAP2,NPTN,CSPG5,STAU2,GABBR1,JPH4,CPLX2,GFAP,PCDH17,PPARGC1A,GLUL,KCNMB4,GPM6B,GPER1,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK5,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,ITPKA,KCNB1,KCNJ10,KIT,LAMA2,NAT8L,MAPT,MEF2C,MYO6,NCAM1,NEUROD2,NF1,NOS1,NRGN,NTRK2,OPHN1,OXTR,NLGN3,SERPINE2,PLCL1,PPP3CA,PPP3CB,PRKCZ,RELN,PTK2,PXK,PTN,RAB3A,RASGRF1,RASGRF2,LRRK2,STX1B,S100B,NLGN4Y,PPP1R9A,CPEB3,BCAN,NLGN1,CLSTN1,SLC1A3,SLC6A1,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCA,IQSEC2,CLSTN2,NCDN,STAU1,STX1A,STXBP1,SYT11,SYN1,ARC,SYP,SYT1,TAC1,TACR1,CNTN2,CUX2,CRTC1,NR2E1,TNR,ZMYND8,VGF,WNT7A,CELF4,LRP8,NETO2,NETO1,JPH3" GO: Biological Process GO:0031175 neuron projection development 5.18E-40 5.08E-36 5.08E-37 4.96E-36 343 953 "ACHE,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,ADORA2A,UNC5A,LRFN2,KIDINS220,LRRC7,SEMA6A,ALCAM,MRTFA,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,NUMB,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CDK5R1,RAB29,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,CBFA2T2,NEURL1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,CTNND2,RIMS2,BOC,KIF26A,IST1,DBN1,DCC,ZEB2,KIAA0319,MAGI2,BLOC1S6,PLPPR4,SNAP91,NTM,DLG4,GRIN3A,DMD,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,ATL1,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G2,ELAVL4,SEZ6,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,ACSL4,PTK2B,TUBB3,EFEMP1,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,PDLIM5,USP21,NPTN,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,ATP8A2,GBX2,GFAP,GFRA1,KIRREL3,NTNG2,GLI2,GNAO1,GPM6A,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,RNF165,PTPN5,IL1RAPL1,LINGO1,HMGB1,HNRNPK,NEGR1,ATCAY,RBPJ,DOCK7,KNDC1,ITPKA,JAK2,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,CPNE9,GIT1,DBNL,BLOC1S2,MT3,MTR,MYO6,NBL1,NCAM1,NEFM,NEFH,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OMG,OPA1,OPHN1,PAK3,PALM,PAX6,NLGN3,SERPINE2,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,MAPK9,RELN,KLK6,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,RAB3A,RASGRF1,FEZF2,CRTAC1,RET,ROBO1,ROBO2,LRRK2,RXRA,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,SGK1,PPP1R9A,ARX,CPEB3,NTNG1,SLITRK3,NLGN1,PREX2,BTBD3,LRRC55,CCDC88A,TRIM67,EFHD1,SLIT1,RIMS1,SNAP25,PALLD,MYO16,USP33,TNIK,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,EPB41L3,NCDN,MAPK8IP3,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,ACSL6,CUX2,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DICER1,SIRT1,THBS4,TIAM1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,ZMYND8,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,WNT7A,ZIC2,NDRG4,DPYSL5,PLPPR5,LRP8,RGMA,GDPD5,STMN4,PRDM8,SEMA3B,ITM2C,FZD3,RTN4,VANGL2,SLC39A12" GO: Biological Process GO:0007417 central nervous system development 9.91E-40 9.72E-36 8.83E-37 8.63E-36 355 1002 "ABAT,ABR,ASIC2,ARID1A,NDRG2,DSCAML1,ADORA2A,NLGN4X,PCDH19,AGT,NME5,NR0B1,AK2,MRTFA,BIN1,OGT,SEMA7A,APAF1,APLP1,APP,SHROOM2,SPTBN4,ARRB2,ASCL1,ASPA,CHRD,NCOA1,NUMB,DYNLL1,ATM,ATP2B1,ATP2B2,ADAM23,BBS2,NRP2,BID,CDK5R1,MYRF,CDK5R2,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,INA,SYNGR3,NEURL1,CDC42,CDH2,DCLK1,NOG,NUMBL,GPR37L1,ADGRG1,CHRNB2,SLIT2,LHX2,NRXN1,CLU,TPP1,VAX2,QKI,NIPBL,CNTN1,WHRN,AKAP5,SLC4A7,HAPLN1,SLC32A1,NCOR1,NCOR2,AATK,TENM4,CSF1R,CHD5,VCAN,NCAN,CNTNAP2,PLXNA4,SLITRK5,CTNND1,CX3CR1,ECE2,SNPH,DBI,DCC,DCT,ZEB2,ARNT2,SEC16A,DLX1,OLIG1,MED12,TRAPPC9,CDON,DPYSL2,DRD1,DRP2,ATN1,RCAN1,SEZ6L2,EFNA2,EGFR,EML1,EMX2,EN2,OLIG2,SEZ6,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CEND1,EZH1,FABP7,DLC1,PRMT5,SEC24B,FGF13,ACTL6B,FGFR1,FGFR3,HPCAL4,FOXG1,FOXO3,AFF2,TACC2,AK8,DLL3,TBR1,NRG3,FYN,GABRA4,GABRA5,GABRB1,NKX6-2,SALL3,NCKAP1,DISC1,GART,WASF3,DNER,GBX2,GFAP,PPARGC1A,KIRREL3,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,GRIK1,GRIN1,GSN,KIF3A,LINGO1,PADI2,HAPLN2,HNMT,HNRNPK,TLX1,HPCA,HTR5A,IGF1,ZIC5,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SLC6A17,ITGAM,KCNA1,KCNC1,KCNC2,KCNJ10,KCNK3,STMN1,LIG4,SMAD1,SMAD9,MAG,MAOB,MAP2,MAPT,MBD1,MBP,SHC3,AFDN,MOG,ADAM22,MT3,TAGLN3,MDGA1,MYCN,NCAM1,NEFH,NEUROD1,NEUROD2,NF1,NFIX,NHLH1,NKX2-2,NNAT,NODAL,NPY,NOVA1,NPTX1,NRCAM,NRGN,NTRK2,NTRK3,OGDH,OMG,OXTR,PAX6,PCDH9,ENPP2,PFKFB3,NLGN3,SERPINE2,SERPINI1,PKD1,PLP1,PCDH18,MAPKAP1,SEPT4,MBOAT7,FA2H,POU3F2,POU3F4,POU6F1,MED1,PPP3CC,MAPK3,MAPK9,HYDIN,PROX1,RELN,KLK6,MDGA2,PTCH1,PTK2,PTN,PTPRZ1,PEX5,FAT4,ROGDI,FEZF2,CRTAC1,RFX4,ROBO1,ROBO2,RORB,LRRK2,SOX8,ATAT1,WLS,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,SOX6,KIF27,TRA2B,SH3GL2,SH3GL3,ARX,FUZ,BCAN,SLC1A2,RPH3A,BTBD3,ZNF430,SLC6A11,SLC8A1,RAB3GAP1,SLC8A3,SIRT2,CDK5RAP3,SLIT1,SMARCA4,SMARCC2,CDK5RAP2,IFT122,FAIM2,MYO16,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,CLUAP1,MYCBP2,SSTR1,SSTR2,ZC4H2,MAPK8IP3,TTBK2,PLCB1,SYT1,SYT4,TACC1,TAL1,UNC5D,CNTN2,AGTPBP1,SATB2,TCF7L2,ZEB1,RPGRIP1L,SZT2,DICER1,CHST8,CDH22,THRA,TIMP4,TLR4,NR2E1,TNR,TP53BP2,RBFOX2,SEZ6L,NR2C2,TSC1,UBE3A,UGT8,CCDC14,VLDLR,WNT7A,WRN,XRCC4,ZIC1,ZIC2,NDRG4,SPHK2,ZBTB16,CA10,LRP8,GDPD5,PRDM8,RNF103,NAV2,SLC17A7,KCNAB1,FZD3,RTN4,IFT88,SLC4A10" GO: Biological Process GO:0030030 cell projection organization 2.14E-39 2.10E-35 1.75E-36 1.71E-35 459 1423 "TTYH1,ACHE,ACTN2,GPRIN1,DSCAML1,SLITRK1,ADCY6,SLC12A5,ERMN,ADORA2A,UNC5A,LRFN2,KIDINS220,TBC1D14,NME5,WDR35,CC2D2A,LRRC7,SEMA6A,ALCAM,CEP126,MRTFA,LRFN1,ANK3,SEMA7A,FGD2,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,MARK4,CAPRIN2,NUMB,DYNLL1,ATP2B2,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,MTMR2,RAB29,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,CBFA2T2,NEURL1,SEPT7,CDC42,CDH2,DCLK1,EVI5L,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,QKI,MAP4K4,CCDC151,ARHGEF6,CNR1,PICK1,CNTN1,WHRN,AKAP5,RTTN,BAG4,SH2B1,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,CNTNAP2,PLXNA4,SLITRK5,PPP1R16B,ARHGEF4,CTNND2,RIMS2,USP6NL,BOC,ARHGAP24,HDAC4,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,DCC,ZEB2,KIAA0319,MAGI2,BLOC1S6,PLPPR4,SNAP91,NTM,DLG4,GRIN3A,DMD,NYAP1,DNAH9,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,E2F5,USH1C,WDPCP,ATL1,SEMA3D,FRY,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,PLXNC1,EIF4G2,TENM1,PLEKHA1,ELAVL4,PLEKHO1,DMTN,MTSS1L,SEZ6,EPHA5,EPHB1,STX2,ERBB2,CDKL3,ETV1,ADGRV1,NRN1,SH3YL1,TBC1D16,ACSL4,PTK2B,TUBB3,TUBB4A,EFEMP1,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,CAMSAP1,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,TMEM107,PDLIM5,USP21,NPTN,STAU2,TBR1,BRSK1,FYN,CHL1,RAPGEF6,NCKAP1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,INPP5K,WASF3,GBX2,GFAP,GFRA1,KIRREL3,NTNG2,GLI2,GNAO1,GPM6A,CECR2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,GSN,KIF3A,RNF165,PTPN5,IL1RAPL1,RABL2A,LINGO1,PACSIN2,HMGB1,HNRNPK,CFAP126,NEGR1,HSP90AA1,ATCAY,RBPJ,DOCK7,KNDC1,HES5,ITPKA,JAK2,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,ZFYVE27,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,CPNE9,GIT1,DBNL,BLOC1S2,MT3,MTR,MYO6,MYO7A,NBL1,NCAM1,NEFM,NEFH,CCDC13,NEK1,NFE2L2,NPY,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,ODF2,OMG,OPA1,OPHN1,P2RX7,PAK3,PALM,PAX6,ENPP2,NLGN3,SERPINE2,SSH1,SEMA5B,SNX10,PLP1,PLXNB1,PLXNB3,PMP22,PRRX1,SPATA6,PACSIN1,FAT3,POU3F2,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK3,MAPK8,MAPK9,HYDIN,RELN,KLK6,BCAS3,LAMA1,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,STRC,TMEM231,RAB3A,CEP97,CCDC40,FAT4,RAP1GAP,RASGRF1,FEZF2,RDX,CRTAC1,RET,RFX2,RFX3,RFX4,KCTD17,ROBO1,ROBO2,GLDN,LRRK2,RXRA,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,KIF27,SGK1,PPP1R9A,ARX,CPEB3,FUZ,NTNG1,SLITRK3,NLGN1,DZIP1,ABLIM3,PREX2,BTBD3,LRRC55,CCDC88A,TRIM67,EFHD1,SLIT1,TTC17,IFT122,RIMS1,SNAP25,PALLD,MYO16,USP33,TNIK,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,RAP1GAP2,SPART,NFASC,CLASP2,TROVE2,EPB41L3,NCDN,MAPK8IP3,TTBK2,KANK1,STXBP1,FGD4,SYT1,COBL,SYT4,SEMA4A,ROBO3,CAMSAP2,UNC5D,CNTN2,ATMIN,ACSL6,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,CRTC1,FRYL,DNAH7,DICER1,SIRT1,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,TPM1,ZMYND8,TSC1,TSC2,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VAV2,VLDLR,TBC1D15,P2RY12,WNT7A,CFAP298,ZIC2,NDRG4,TMEM237,DPYSL5,PLPPR5,LRP8,RGMA,EVI5,GDPD5,STMN4,PRDM8,SEMA3B,PCDH15,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,IFT88,SPATA13" GO: Biological Process GO:0048812 neuron projection morphogenesis 1.56E-38 1.53E-34 1.18E-35 1.15E-34 253 630 "ACHE,DSCAML1,SLITRK1,ADORA2A,UNC5A,LRFN2,KIDINS220,SEMA6A,ALCAM,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,NUMB,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CDK5R1,CACNA1A,DDR1,KALRN,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,AKAP5,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,CTNND2,RIMS2,BOC,KIF26A,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,PLXNC1,EIF4G2,ELAVL4,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,ATP8A2,GBX2,KIRREL3,NTNG2,GLI2,GPM6A,GRIN1,CIT,RNF165,IL1RAPL1,LINGO1,HNRNPK,DOCK7,KNDC1,ITPKA,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,MAP2,MAP6,MAPT,MATN2,MBP,CPNE9,DBNL,MT3,NBL1,NCAM1,NEFH,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OMG,OPHN1,PAK3,PAX6,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,PACSIN1,POU3F2,PPP3CA,PPP3CB,PRKCZ,MAPK3,MAPK8,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,RAB3A,FEZF2,RET,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,SGK1,PPP1R9A,ARX,NTNG1,SLITRK3,NLGN1,PREX2,BTBD3,LRRC55,SLIT1,RIMS1,MYO16,USP33,TNIK,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,EPB41L3,MAPK8IP3,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,CUX2,SZT2,SYNE1,OBSL1,DICER1,THBS4,TIAM1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,WNT7A,ZIC2,DPYSL5,LRP8,RGMA,PRDM8,SEMA3B,FZD3,RTN4,VANGL2" GO: Biological Process GO:0007267 cell-cell signaling 1.83E-38 1.79E-34 1.28E-35 1.25E-34 410 1233 "ABAT,SYN3,ASIC2,ASIC1,ACHE,ABHD6,ADCY5,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,LRFN2,ADRB2,NLGN4X,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,AMH,AMPH,LRFN1,ANK2,PPFIA4,PPFIA2,CNIH2,PPFIA1,PKP4,APBA2,ALS2,PPFIA3,MADD,CASK,ARNTL,ARRB1,ARRB2,CADPS,PDE8B,ATP1A2,ATP2A2,ATP2B2,BCHE,HCN2,FGF17,CDK5R1,SYNJ1,ARHGEF7,BTK,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,SYT6,BRSK2,CBLN1,SHISA7,CCKBR,CD86,CD38,NEURL1,DGKI,CDC42,CDH8,LGI1,DLGAP2,DLGAP1,CACNA2D2,ADGRG1,CHRM1,CHRM4,CHRNA4,CHRNB2,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,MAP4K4,CNR1,PICK1,AKAP5,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SLC32A1,SNCAIP,SIPA1L1,RIMS4,SLITRK5,CTNND2,RIMS2,CX3CR1,ECE2,SNPH,RIMS3,DAPK1,DBI,DBN1,CNIH3,C2CD2L,BLOC1S6,LYPD1,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,DNM1,DMPK,SHANK1,SLC12A6,DRD1,DTNA,EDN1,EDN3,SYT15,SIDT2,CACNG7,EFNA2,EFNA3,EFNB3,EGFR,EGR3,SEZ6,EPHA5,KCNMB2,STX2,ERBB4,RTN3,CACNG3,CACNG2,PTK2B,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,BAIAP2,SYT3,NPTN,CSPG5,STAU2,BRSK1,OGA,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,ILDR2,GAD1,GAD2,JPH4,GALR1,SYT17,CPLX2,CPLX1,GCK,GDF9,GFAP,PCDH17,PPARGC1A,GJB1,GLI2,GLRB,GLS,GLUL,KCNMB4,GNAS,GPM6B,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,PTGDR2,HRH3,HMGCR,HNRNPK,SHISA6,HTR2A,ICA1,MYLK2,LRRTM1,C2CD4C,ITPKA,JAK2,KCNA1,KCNB1,KCNC2,KCND2,KCNJ10,KCNJ11,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,SYTL4,NAT8L,MAPT,MBP,SYT9,SHC3,MEF2C,AFDN,MYO5A,MYO6,MYT1,NCAM1,NDP,NELL2,NEUROD1,NEUROD2,NF1,NNAT,NODAL,NOS1,NPY,NOVA1,NPTX1,NPTX2,NRGN,NTRK2,NUCB2,OPHN1,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PCDH8,PCSK1,PCSK5,PDE1C,PDE3B,PDYN,PENK,TMOD2,PFKFB2,NLGN3,SERPINE2,PLCL1,PLP1,PMP22,TRHDE,SH3KBP1,PPP3CA,PPP3CB,PRKCG,PRKCZ,RELN,SYTL2,PTHLH,PTK2,PXK,PTN,PTPRD,PTPRN,PTPRN2,RAB3A,RASGRF1,RASGRF2,GAL3ST4,RFX3,RGS10,RIT2,LRRK2,LGR4,WLS,KCNIP2,STX1B,S100B,ATXN1,LRFN5,SCN2B,SCN4B,SMPD3,NLGN4Y,SCG5,PPP1R9A,CPEB3,BCAN,SYBU,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLC12A4,NAPB,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,SCN3B,SOX11,KIF1B,IQSEC2,CLSTN2,SST,SSTR1,SSTR2,NCDN,STAU1,STX1A,STXBP1,SYT11,ABCC8,PLCB1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,TAC1,TACR1,CNTN2,CUX2,TCF7L2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,CRTC1,TEK,SIRT1,CRB1,TIAM1,TJP1,NR2E1,TNR,RASD2,TRH,STXBP4,TRPM2,ZMYND8,KCNE5,VGF,VIPR2,VSNL1,WNT7A,TRIM9,CELF4,LRP8,SEMA3B,SLC17A7,GJC2,NETO2,NETO1,JPH3" GO: Biological Process GO:0051960 regulation of nervous system development 6.41E-37 6.28E-33 4.19E-34 4.09E-33 317 881 "ASIC2,ACHE,SLITRK1,ADCY6,KIDINS220,BEND6,DISP3,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,BRINP2,CHRD,NCOA1,NUMB,ADGRB1,ADGRB2,ADGRB3,BMP7,CDK5R1,SYNJ1,MTMR2,RAB29,MYRF,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,CBLN1,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,CPNE6,NRXN3,NRXN1,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1,TENM4,RGS6,FEZ1,SIPA1L1,PLXNA4,SLITRK5,RIMS2,CX3CR1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,KIAA0319,MAGI2,NTM,DLX1,DMD,CDON,DNM2,SHANK1,DPYSL2,DSCAM,EDNRB,HEYL,SEMA3D,EFNA3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,SEZ6,EPHB1,ERBB4,CDKL3,CEND1,EYA1,PTK2B,EFEMP1,PRMT5,SEC24B,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXG1,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,NPTN,DLL3,STAU2,TBR1,NRG3,FYN,NKX6-2,SYT17,DISC1,ATP8A2,WASF3,GFAP,GLI2,GPER1,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,HNRNPK,NEGR1,IGF1,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SCRT2,BRINP3,LRRTM3,LRRTM1,ITPKA,KIT,L1CAM,LRRC4B,LIG4,MAG,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,CPNE9,MT3,MDGA1,MYCN,NAP1L2,NBL1,NEUROD1,NEUROD2,NF1,NFE2L2,NKX2-2,NOS1,NRCAM,NTRK2,NTRK3,OMG,OPA1,OXTR,PAK3,PALM,PAX6,PBX1,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,MED1,LRRN3,PPP3CA,PRKACB,PROX1,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RET,RFX4,ROBO1,ROBO2,LRRK2,SYNDIG1,SOX8,RXRA,RXRG,SALL1,SEMA6D,ATXN1,DRAXIN,LRRTM4,SGK1,PPP1R9A,CPEB3,SLITRK3,NLGN1,CLSTN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SLIT1,CDK5RAP2,SMARCD3,IFT122,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,SPP1,KDM4C,RAP1GAP2,SPART,CLASP2,CLSTN2,MAPK8IP3,KANK1,SYT1,COBL,SYT4,SEMA4A,UNC5D,CNTN2,ADGRL3,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,TF,DICER1,SIRT1,GPR161,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,PARD3,TNR,LRRC24,ZMYND8,LRTM2,TTC3,EIF4ENIF1,GORASP1,FLRT2,FLRT1,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,PLPPR5,LRP8,RGMA,GDPD5,SEMA3B,ITM2C,FZD3,RTN4,VANGL2,SLC39A12,CBLN2" GO: Biological Process GO:0032990 cell part morphogenesis 4.12E-35 4.04E-31 2.52E-32 2.46E-31 324 925 "ACHE,DSCAML1,SLITRK1,ADORA2A,UNC5A,LRFN2,KIDINS220,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,NUMB,DYNLL1,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,NEURL1,SEPT7,CDH2,DCLK1,EVI5L,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,CCDC151,AKAP5,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,CTNND2,RIMS2,USP6NL,BOC,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DMD,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,DNM1L,FIS1,WDPCP,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,PLXNC1,EIF4G2,ELAVL4,PLEKHO1,COQ7,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,TUBB3,ZMYND10,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,TMEM107,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,GBX2,KIRREL3,NTNG2,GLI2,GPM6A,GRIN1,CIT,GSN,KIF3A,RNF165,IL1RAPL1,RABL2A,LINGO1,PACSIN2,HNRNPK,DOCK7,KNDC1,ITPKA,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,POC1B,CPNE9,DBNL,MT3,NBL1,NCAM1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,ODF2,OMG,OPHN1,PAK3,PAX6,ENPP2,NLGN3,SSH1,SEMA5B,SNX10,PLXNB1,PLXNB3,SPATA6,PACSIN1,POU3F2,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK3,MAPK8,HYDIN,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,TMEM231,RAB3A,PID1,CEP97,CCDC40,FEZF2,RET,RFX2,RFX3,RFX4,KCTD17,MYH14,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,KIF27,SGK1,PPP1R9A,ARX,FUZ,NTNG1,SLITRK3,NLGN1,DZIP1,NUBPL,ABLIM3,PREX2,BTBD3,LRRC55,SLIT1,IFT122,RIMS1,MYO16,USP33,TNIK,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,TROVE2,EPB41L3,MAPK8IP3,TTBK2,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,ATMIN,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,DNAH7,DICER1,THBS4,TIAM1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,TBC1D15,WNT7A,CFAP298,ZIC2,TMEM237,DPYSL5,MFF,LRP8,RGMA,EVI5,PRDM8,SEMA3B,PCDH15,FZD3,RTN4,VANGL2,IFT88" GO: Biological Process GO:0048858 cell projection morphogenesis 1.87E-34 1.83E-30 1.08E-31 1.05E-30 317 904 "ACHE,DSCAML1,SLITRK1,ADORA2A,UNC5A,LRFN2,KIDINS220,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,ANK3,SEMA7A,CNTNAP1,APBB1,APBB2,APC,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,NUMB,DYNLL1,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,WASF1,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,NEURL1,SEPT7,CDH2,DCLK1,EVI5L,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,CCDC151,AKAP5,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,CTNND2,RIMS2,USP6NL,BOC,KIF26A,TBC1D5,KIAA0586,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DMD,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,WDPCP,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,PLXNC1,EIF4G2,ELAVL4,PLEKHO1,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,TUBB3,ZMYND10,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,TMEM107,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,GBX2,KIRREL3,NTNG2,GLI2,GPM6A,GRIN1,CIT,GSN,KIF3A,RNF165,IL1RAPL1,RABL2A,LINGO1,PACSIN2,HNRNPK,DOCK7,KNDC1,ITPKA,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIFR,MAG,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,POC1B,CPNE9,DBNL,MT3,NBL1,NCAM1,NEFH,CCDC13,NEK1,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,ODF2,OMG,OPHN1,PAK3,PAX6,ENPP2,NLGN3,SSH1,SEMA5B,SNX10,PLXNB1,PLXNB3,SPATA6,PACSIN1,POU3F2,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK3,MAPK8,HYDIN,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,TMEM231,RAB3A,CEP97,CCDC40,FEZF2,RET,RFX2,RFX3,RFX4,KCTD17,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,DRAXIN,ATXN2,LRFN5,KIF27,SGK1,PPP1R9A,ARX,FUZ,NTNG1,SLITRK3,NLGN1,DZIP1,ABLIM3,PREX2,BTBD3,LRRC55,SLIT1,IFT122,RIMS1,MYO16,USP33,TNIK,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,TROVE2,EPB41L3,MAPK8IP3,TTBK2,KANK1,STXBP1,SYT1,COBL,SYT4,SEMA4A,ROBO3,UNC5D,CNTN2,ATMIN,CUX2,RPGRIP1L,SZT2,SYNE1,OBSL1,DNAH7,DICER1,THBS4,TIAM1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,LRTM2,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,TBC1D15,WNT7A,CFAP298,ZIC2,TMEM237,DPYSL5,LRP8,RGMA,EVI5,PRDM8,SEMA3B,PCDH15,FZD3,RTN4,VANGL2,IFT88" GO: Biological Process GO:0032989 cellular component morphogenesis 1.28E-33 1.26E-29 7.00E-31 6.84E-30 444 1430 "ACHE,ACTN1,ACTN2,FMNL2,DSCAML1,SLITRK1,ADD1,AXIN2,CDC7,ERMN,ADORA2A,UNC5A,LRFN2,KIDINS220,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,ANK2,ANK3,SEMA7A,FGD2,ANXA7,CNTNAP1,APBB1,APBB2,APC,EPB41L5,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SHROOM2,SEMA4G,PRX,SPTBN4,ARHGDIA,CAPRIN2,DACT3,NUMB,DYNLL1,ATP2B2,ADAM15,ADGRB1,ADGRB3,BBS2,NRP2,CFLAR,BMP7,BMPR1B,CDK5R1,ARHGEF7,MTMR2,WASF1,LDLRAD4,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,CAPN3,BRSK2,ISPD,MAP7,CCK,FMNL3,ARHGEF1,NEURL1,ARHGEF2,SEPT7,CDC42,CDH2,DCLK1,ZMYM4,EVI5L,LGI1,NOG,NUMBL,CFL2,CHN1,CHRNB2,TAOK2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,CCDC151,AKAP5,TBPL1,ZNF385A,CRMP1,AATK,TENM4,CSF1R,FEZ2,FEZ1,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,SLITRK5,CTNND2,RIMS2,USP6NL,BOC,MYADM,KIF26A,TBC1D5,KIAA0586,IST1,DAPK3,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DMD,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,DNM1L,FIS1,WDPCP,EDN1,ATL1,HEYL,SEMA3D,FRY,SIDT2,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,PLXNC1,EIF4G2,ELAVL4,PLEKHO1,EPB41,EPB41L2,COQ7,DMTN,EPHA5,EPHB1,EPS8,ERBB2,ERCC2,CDKL3,ETV1,NRN1,TBC1D16,PTK2B,TUBB3,DLC1,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FGR,CAMSAP1,FOXG1,CAP2,FOXF2,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,TMEM107,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,WASF3,GBX2,GCNT2,KIRREL3,NTNG2,TTBK1,GLI2,LOXL3,FERMT2,GPM6A,GRIN1,CIT,GSN,KIF3A,RNF165,IL1RAPL1,BVES,RABL2A,LINGO1,MAEL,HAS2,PACSIN2,HNRNPK,AGFG1,RBPJ,DOCK7,KNDC1,ITGA7,ITGAV,ITPKA,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIMS1,MAG,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,MKLN1,CPNE9,DBNL,MT3,MYH3,MYH6,MYO7A,NBL1,NCAM1,NEFH,CCDC13,NEK1,NODAL,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,ODF2,OMG,OPHN1,P2RX7,PAK3,PALM,PAX6,PDGFRA,ENPP2,TMOD2,NLGN3,SSH1,SEMA5B,SNX10,PLXNB1,PLXNB3,PMP22,SPATA6,PACSIN1,FAT3,SH3KBP1,POU3F2,MED1,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK3,MAPK8,MAPK9,FITM2,HYDIN,PROX1,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,PTPRZ1,STRC,TMEM231,RAB3A,PID1,CEP97,CCDC40,FEZF2,RDX,RET,RFX2,RFX3,RFX4,KCTD17,MYH14,ROBO1,ROBO2,TMEM100,LRRK2,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,LRFN5,SOX6,KIF27,SGK1,PPP1R9A,ARX,FUZ,NTNG1,FHOD3,ST6GAL1,SLITRK3,NLGN1,DZIP1,NUBPL,ABLIM3,SLC1A3,PREX2,BTBD3,LRRC55,RADIL,SLIT1,SMARCA4,IFT122,RIMS1,PALLD,MYO16,USP33,TNIK,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,TROVE2,EPB41L3,LARP4,SS18,MAPK8IP3,TTBK2,PHLDB1,KANK1,STXBP1,FGD4,ARC,SYT1,COBL,SYT4,SEMA4A,ROBO3,TAL1,UNC5D,CNTN2,ATMIN,CUX2,TCF7L2,RPGRIP1L,CLASP1,SZT2,SYNE1,OBSL1,FRYL,TEK,DNAH7,DICER1,TGFBR3,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,TMOD1,PARD3,TNR,RBFOX2,TPM1,LRTM2,TTC3,CADM1,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,TBC1D15,WIPF1,WNT7A,CFAP298,ZIC2,CRB2,TMEM237,DPYSL5,MFF,LRP8,RGMA,EVI5,PRDM8,SEMA3B,PCDH15,WIPF2,FZD3,RTN4,JMJD1C,VANGL2,FRMD6,IFT88" GO: Biological Process GO:0000902 cell morphogenesis 1.16E-32 1.14E-28 6.00E-30 5.86E-29 419 1337 "ACHE,ACTN1,FMNL2,DSCAML1,SLITRK1,ADD1,AXIN2,CDC7,ERMN,ADORA2A,UNC5A,LRFN2,KIDINS220,TBC1D14,NME5,WDR35,CC2D2A,SEMA6A,ALCAM,CEP126,LRFN1,ANK3,SEMA7A,FGD2,ANXA7,CNTNAP1,APBB1,APBB2,APC,EPB41L5,GAS7,ALS2,LRRC4C,APP,SHTN1,CPNE5,SHROOM2,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,DACT3,NUMB,DYNLL1,ATP2B2,ADAM15,ADGRB1,ADGRB3,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,WASF1,LDLRAD4,CFAP410,CACNA1A,DDR1,KALRN,HAP1,CAMK2A,CAMK2B,BRSK2,ISPD,MAP7,CCK,FMNL3,ARHGEF1,NEURL1,ARHGEF2,SEPT7,CDC42,CDH2,DCLK1,ZMYM4,EVI5L,LGI1,NOG,NUMBL,CHN1,CHRNB2,TAOK2,SLIT2,LHX2,CPNE6,NRXN3,NRXN1,CLU,NGEF,VAX2,CCDC151,AKAP5,ZNF385A,CRMP1,AATK,CSF1R,FEZ2,FEZ1,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,SLITRK5,CTNND2,RIMS2,USP6NL,BOC,MYADM,KIF26A,TBC1D5,KIAA0586,IST1,DAPK3,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DMD,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,WDPCP,ATL1,HEYL,SEMA3D,FRY,SIDT2,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,PLXNC1,EIF4G2,ELAVL4,PLEKHO1,EPB41,EPB41L2,DMTN,EPHA5,EPHB1,EPS8,ERBB2,CDKL3,ETV1,NRN1,TBC1D16,PTK2B,TUBB3,DLC1,ZMYND10,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FGR,CAMSAP1,FOXG1,CAP2,FOXF2,SEMA6C,EVL,SEMA4D,SYT3,DPYSL4,TMEM107,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,WASF3,GBX2,GCNT2,KIRREL3,NTNG2,TTBK1,GLI2,LOXL3,FERMT2,GPM6A,GRIN1,CIT,GSN,KIF3A,RNF165,IL1RAPL1,BVES,RABL2A,LINGO1,MAEL,HAS2,PACSIN2,HNRNPK,RBPJ,DOCK7,KNDC1,ITGA7,ITGAV,ITPKA,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,STMN1,LIFR,LIMS1,MAG,MAP2,MAP4,MAP6,MAPT,MATN2,MBP,MEF2C,POC1B,MKLN1,CPNE9,DBNL,MT3,MYO7A,NBL1,NCAM1,NEFH,CCDC13,NEK1,NODAL,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OCRL,ODF2,OMG,OPHN1,P2RX7,PAK3,PALM,PAX6,ENPP2,NLGN3,SSH1,SEMA5B,SNX10,PLXNB1,PLXNB3,SPATA6,PACSIN1,FAT3,SH3KBP1,POU3F2,MED1,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK3,MAPK8,MAPK9,FITM2,HYDIN,PROX1,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,PTPRZ1,STRC,TMEM231,RAB3A,CEP97,CCDC40,FEZF2,RDX,RET,RFX2,RFX3,RFX4,KCTD17,MYH14,ROBO1,ROBO2,TMEM100,LRRK2,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,LRFN5,SOX6,KIF27,SGK1,PPP1R9A,ARX,FUZ,NTNG1,ST6GAL1,SLITRK3,NLGN1,DZIP1,ABLIM3,SLC1A3,PREX2,BTBD3,LRRC55,RADIL,SLIT1,SMARCA4,IFT122,RIMS1,PALLD,MYO16,USP33,TNIK,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,TROVE2,EPB41L3,LARP4,SS18,MAPK8IP3,TTBK2,PHLDB1,KANK1,STXBP1,FGD4,ARC,SYT1,COBL,SYT4,SEMA4A,ROBO3,TAL1,UNC5D,CNTN2,ATMIN,CUX2,TCF7L2,RPGRIP1L,CLASP1,SZT2,SYNE1,OBSL1,FRYL,TEK,DNAH7,DICER1,TGFBR3,THBS4,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,PARD3,TNR,RBFOX2,TPM1,LRTM2,TTC3,CADM1,UCHL1,GORASP1,UGT8,FLRT2,FLRT1,VLDLR,TBC1D15,WIPF1,WNT7A,CFAP298,ZIC2,CRB2,TMEM237,DPYSL5,LRP8,RGMA,EVI5,PRDM8,SEMA3B,PCDH15,WIPF2,FZD3,RTN4,JMJD1C,VANGL2,FRMD6,IFT88" GO: Biological Process GO:0048667 cell morphogenesis involved in neuron differentiation 2.86E-32 2.80E-28 1.40E-29 1.37E-28 229 590 "ACHE,DSCAML1,SLITRK1,UNC5A,LRFN2,KIDINS220,SEMA6A,ALCAM,LRFN1,ANK3,SEMA7A,APBB1,APBB2,APC,ALS2,LRRC4C,APP,SHTN1,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,NUMB,ATP2B2,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CDK5R1,CACNA1A,KALRN,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,NRXN3,NRXN1,NGEF,VAX2,AKAP5,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,CTNND2,BOC,KIF26A,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,WDPCP,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EIF4G2,ELAVL4,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,SEC24B,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,DISC1,ATP8A2,GBX2,NTNG2,GLI2,GRIN1,CIT,RNF165,IL1RAPL1,LINGO1,DOCK7,KNDC1,ITPKA,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,MAG,MAP2,MAP6,MAPT,MATN2,MBP,MEF2C,MT3,MYO7A,NCAM1,NEFH,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OMG,OPHN1,PAK3,PAX6,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,POU3F2,PPP3CA,PPP3CB,MAPK3,MAPK8,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,STRC,RAB3A,FEZF2,RET,ROBO1,ROBO2,LRRK2,S100B,SEMA6D,DRAXIN,LRFN5,SGK1,PPP1R9A,ARX,NTNG1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,SLIT1,USP33,TNIK,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,MAPK8IP3,STXBP1,COBL,SEMA4A,ROBO3,UNC5D,CNTN2,CUX2,SZT2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,PARD3,TNR,RBFOX2,LRTM2,UCHL1,GORASP1,FLRT2,VLDLR,WNT7A,ZIC2,DPYSL5,LRP8,RGMA,PRDM8,SEMA3B,PCDH15,FZD3,RTN4,VANGL2" GO: Biological Process GO:0050803 regulation of synapse structure or activity 5.76E-32 5.65E-28 2.69E-29 2.63E-28 135 272 "ASIC2,ABHD6,SLITRK1,ADORA1,ADORA2A,AGT,PPFIA3,APP,ATP2B2,ADGRB1,ADGRB2,ADGRB3,CALB1,CAMK2A,CAMK2B,CBLN1,SHISA7,CD38,NEURL1,DGKI,CDC42,CDH2,CHRNB2,NRXN3,NRXN1,SLC24A2,PICK1,SIPA1L1,NCAN,SLITRK5,CTNND2,CX3CR1,FRMPD4,DBI,DBN1,MAGI2,DLG4,DMPK,DRD1,EPHB1,PTK2B,FGF14,BAIAP2,PDLIM5,NPTN,STAU2,JPH4,DISC1,CPLX2,GFAP,PCDH17,GRIA1,GRIK1,GRIK2,GRIN1,NR3C1,GRM5,PTPN5,HNRNPK,SHISA6,MYLK2,LRRTM3,LRRTM1,ITPKA,KCNB1,KCNJ10,KIT,LRRC4B,MAPT,MEF2C,MDGA1,MYO6,NCAM1,NEUROD2,NF1,NOS1,NRGN,NTRK2,NTRK3,OXTR,NLGN3,SERPINE2,LRRN3,PPP3CB,PRKCZ,RELN,PTK2,PTN,RAB3A,RASGRF1,RASGRF2,ROBO2,SYNDIG1,S100B,LRRTM4,PPP1R9A,CPEB3,SLITRK3,BCAN,NLGN1,CLSTN1,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SLIT1,SORCS3,RIMS1,SNAP25,SNCA,IQSEC2,CLSTN2,LRRC4,NCDN,STAU1,STXBP1,ARC,SYP,CNTN2,ADGRL3,CUX2,CRTC1,BHLHB9,NR2E1,TNR,LRRC24,ZMYND8,LRTM2,FLRT2,FLRT1,VGF,WNT7A,NETO1,CBLN2,JPH3" GO: Biological Process GO:0050767 regulation of neurogenesis 9.74E-31 9.55E-27 4.34E-28 4.24E-27 277 784 "ACHE,ADCY6,KIDINS220,BEND6,DISP3,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,ADGRB3,BMP7,CDK5R1,SYNJ1,RAB29,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,CSF1,TENM4,RGS6,FEZ1,SIPA1L1,PLXNA4,RIMS2,CX3CR1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,KIAA0319,MAGI2,NTM,DLX1,DMD,CDON,DNM2,SHANK1,DPYSL2,DSCAM,EDNRB,HEYL,SEMA3D,EFNA3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,SEZ6,ERBB4,CDKL3,EYA1,PTK2B,EFEMP1,PRMT5,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,FOXG1,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,NPTN,DLL3,STAU2,TBR1,NRG3,FYN,NKX6-2,SYT17,DISC1,ATP8A2,GFAP,GLI2,GPER1,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,HNRNPK,NEGR1,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SCRT2,BRINP3,ITPKA,KIT,L1CAM,LIG4,MAG,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,CPNE9,MT3,MYCN,NAP1L2,NBL1,NEUROD1,NEUROD2,NF1,NFE2L2,NKX2-2,NOS1,NRCAM,NTRK2,NTRK3,OMG,OPA1,PAK3,PALM,PAX6,PBX1,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,MED1,PPP3CA,PROX1,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RET,ROBO1,ROBO2,LRRK2,SOX8,SALL1,SEMA6D,ATXN1,DRAXIN,SGK1,PPP1R9A,CPEB3,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SLIT1,CDK5RAP2,SMARCD3,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,SPP1,KDM4C,RAP1GAP2,SPART,CLASP2,MAPK8IP3,KANK1,SYT1,COBL,SYT4,SEMA4A,UNC5D,CNTN2,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,TF,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,TNR,ZMYND8,TTC3,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,PLPPR5,LRP8,RGMA,GDPD5,SEMA3B,ITM2C,FZD3,RTN4,SLC39A12" GO: Biological Process GO:0007610 behavior 4.11E-30 4.03E-26 1.75E-27 1.71E-26 246 671 "ABAT,ASIC1,ADCY5,SLITRK1,ADCY8,SLC12A5,FZD9,ADORA1,ADORA2A,ADRA1B,ADRB2,NLGN4X,AGT,PLA2G6,UNC79,AMPH,ANXA7,APBA2,APBB1,ALS2,DDO,APP,SPTBN4,ARRB2,PDE8B,NCOA1,ASTN1,ATP1A2,ATP1A3,ATP2B2,ADGRB3,BBS2,BCHE,SYNJ1,CACNA1A,CACNA1B,CACNA1E,CACNB4,CALB1,KALRN,CCK,CCKBR,USP2,DGKI,NOG,CIART,CHRNA4,CHRNB2,NRXN3,CLCN3,NRXN1,NRXN2,SLC24A2,CNR1,CNTFR,ZNF385A,CRHBP,CSNK1E,CNTNAP2,SLITRK5,CTNND2,PUM1,CX3CR1,BRINP1,DBI,GIT2,DBN1,LYPD1,DLG4,DNM1,SHANK1,DRD1,DSCAM,RCAN1,SEZ6L2,EFNB3,EGFR,ABI2,EIF4G1,ELAVL4,RCAN2,SEZ6,EPS8,ETV1,CEND1,ATP8A1,PPP1R1B,FGF12,FGF13,FGF14,AFF2,NPTN,TBR1,FYN,GAA,GABRA5,CHL1,GABRG2,GAD1,JPH4,ATP8A2,PCDH17,C1QL1,KIRREL3,HPGDS,GLRB,GLS,GNAO1,PRLHR,MCHR1,GPR37,GRIA1,GRID1,GRIK1,GRIK2,GRIN1,GRIN2D,NR3C1,GRM1,GRM5,GRM7,PTPN5,HRH3,HMGCR,NEGR1,HTR2A,IGF1,LRRTM1,KCNA2,KCND2,KCNJ10,KCNK2,KCNMA1,KIT,FGFBP3,LSAMP,MAPT,SHC3,MEF2C,MEIS1,MEIS2,MMP17,ADAM22,MYO5A,MYO6,NCAM1,NEUROD2,NF1,NOS1,NPY,NOVA1,NPTX2,SLC11A2,NRGN,NTRK2,GPR88,OPRL1,OXTR,P2RY1,KCNK10,PDE1B,PIRT,SLC10A4,PENK,TMOD2,ZDHHC8,NLGN3,SERPINE2,PPARA,PPP3CB,PRKAR1B,PRKCG,PRKCZ,MAPK10,RELN,PTN,PTPRZ1,OXR1,RASGRF1,FEZF2,FIGN,MYH14,MRAP2,LRRK2,KCNIP3,RMI1,S100B,ATXN1,SCN8A,NLGN4Y,SGK1,CPEB3,NLGN1,SLC1A2,SLC1A3,PREX2,SLC6A1,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,SNCA,MBD5,ANKFN1,NPAS3,VPS13A,DNAJC9,PLCB1,ARC,TAC1,TACR1,DDHD2,TAL1,CNTN2,ADGRL3,AGTPBP1,CUX2,CRTC1,THBS4,THRA,BHLHB9,NR2E1,TMOD1,TNR,SEZ6L,RASD2,NR2C2,TRH,TSC1,UCHL1,VLDLR,LGI4,ZIC1,NDRG4,PCDH15,NAV2,SLC17A7,KCNAB1,EPM2A,PAK5,AAAS,IFT88,NETO1,SLC4A10,JPH3" GO: Biological Process GO:0050808 synapse organization 4.74E-29 4.65E-25 1.94E-26 1.89E-25 126 258 "ASIC2,ACHE,SLITRK1,NLGN4X,ANK3,ALS2,APP,ATP2B2,ADGRB1,ADGRB2,ADGRB3,BSN,CACNA1A,CACNB2,CACNB4,CAMK2B,CBLN1,NEURL1,CDC42,CDH2,CACNA2D2,CHRNB2,NRXN3,NRXN1,NRXN2,COL4A5,NCAN,SLITRK5,CTNND2,FRMPD4,SPOCK2,DBN1,MAGI2,DLG4,RAB39B,DMPK,SHANK1,DRD1,DRP2,DSCAM,SEZ6L2,SEZ6,EPHB1,GPHN,ERBB2,ERBB4,CACNG2,PDLIM5,STAU2,DISC1,DNER,PCDH17,C1QL1,KIRREL3,GLRB,GPM6A,PCLO,GRIN1,IL1RAPL1,HNRNPK,LRRTM3,LRRTM1,LRRC4B,MEF2C,DBNL,MDGA1,MYO5A,MYO6,NEUROD2,NFIA,NRCAM,NRDC,NTRK2,NTRK3,OXTR,PAK3,PALM,PCDHGC3,NLGN3,SDK2,LRRN3,RELN,PTK2,PTN,PTPRD,RAB3A,ROBO2,LRRK2,SYNDIG1,LRRTM4,NLGN4Y,PPP1R9A,SLITRK3,NLGN1,CLSTN1,SHANK2,SLIT1,SNCB,SNCA,PDZRN3,NFASC,CLSTN2,ZC4H2,LRRC4,CNTN2,ADGRL3,CUX2,PCDHGC5,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,BHLHB9,TNR,SEZ6L,LRRC24,ZMYND8,TSC1,LRTM2,CADM1,FLRT2,FLRT1,WNT7A,ELFN1,CBLN2" GO: Biological Process GO:0007420 brain development 4.20E-28 4.12E-24 1.65E-25 1.61E-24 263 755 "ABAT,ABR,ARID1A,NDRG2,DSCAML1,NLGN4X,PCDH19,NME5,NR0B1,AK2,MRTFA,OGT,SEMA7A,APAF1,APLP1,APP,SHROOM2,ARRB2,ASCL1,CHRD,NCOA1,NUMB,DYNLL1,ATM,ATP2B1,ATP2B2,BBS2,NRP2,BID,CDK5R1,CDK5R2,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,INA,SYNGR3,NEURL1,CDC42,CDH2,DCLK1,NOG,NUMBL,GPR37L1,ADGRG1,CHRNB2,SLIT2,LHX2,NRXN1,VAX2,NIPBL,CNTN1,WHRN,AKAP5,SLC4A7,SLC32A1,NCOR1,NCOR2,AATK,CSF1R,CHD5,CNTNAP2,PLXNA4,SLITRK5,CTNND1,CX3CR1,ECE2,SNPH,DBI,DCT,ZEB2,ARNT2,SEC16A,DLX1,TRAPPC9,CDON,DPYSL2,DRD1,SEZ6L2,EFNA2,EGFR,EML1,EMX2,EN2,OLIG2,SEZ6,EPHA5,ERBB4,CEND1,EZH1,FABP7,DLC1,SEC24B,FGF13,FGFR1,FGFR3,FOXG1,FOXO3,AFF2,TACC2,AK8,TBR1,NRG3,FYN,GABRA5,SALL3,DISC1,GART,GBX2,PPARGC1A,KIRREL3,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,GRIN1,KIF3A,PADI2,HNMT,HNRNPK,HPCA,HTR5A,IGF1,ZIC5,RBPJ,DOCK7,KNDC1,HES5,SLC6A17,KCNA1,KCNC1,KCNC2,KCNK3,STMN1,SMAD1,SMAD9,MAG,MAOB,MAPT,MBP,AFDN,MT3,MDGA1,NCAM1,NEFH,NEUROD1,NEUROD2,NF1,NFIX,NKX2-2,NNAT,NODAL,NPY,NRGN,NTRK2,OGDH,OXTR,PAX6,PCDH9,PFKFB3,SERPINE2,PLP1,PCDH18,MAPKAP1,SEPT4,MBOAT7,POU3F2,POU3F4,POU6F1,MED1,PPP3CC,HYDIN,PROX1,RELN,PTCH1,PTN,PTPRZ1,PEX5,FAT4,ROGDI,FEZF2,CRTAC1,RFX4,ROBO1,ROBO2,RORB,LRRK2,ATAT1,WLS,SALL1,SEMA6D,DRAXIN,ATXN2,KIF27,TRA2B,ARX,BCAN,SLC1A2,RPH3A,BTBD3,ZNF430,SLC6A11,SLC8A1,RAB3GAP1,SLC8A3,SIRT2,CDK5RAP3,SLIT1,SMARCA4,SMARCC2,CDK5RAP2,FAIM2,MYO16,SOX1,SOX2,SOX3,SSTR1,SSTR2,MAPK8IP3,TTBK2,PLCB1,SYT1,SYT4,TACC1,CNTN2,AGTPBP1,SATB2,TCF7L2,RPGRIP1L,SZT2,DICER1,CDH22,THRA,NR2E1,TNR,RBFOX2,SEZ6L,NR2C2,TSC1,UBE3A,CCDC14,VLDLR,WNT7A,WRN,ZIC1,ZIC2,NDRG4,SPHK2,CA10,LRP8,GDPD5,PRDM8,SLC17A7,KCNAB1,FZD3,RTN4,IFT88,SLC4A10" GO: Biological Process GO:0045664 regulation of neuron differentiation 4.52E-28 4.43E-24 1.70E-25 1.66E-24 237 655 "ACHE,ADCY6,KIDINS220,BEND6,DISP3,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ASCL1,CAPRIN2,BRINP2,NCOA1,NUMB,ADGRB3,BMP7,CDK5R1,RAB29,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,NEURL1,CDH2,NOG,NUMBL,GPR37L1,CHN1,CHRNB2,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,RGS6,FEZ1,SIPA1L1,PLXNA4,RIMS2,IST1,BRINP1,DBN1,DCC,ZEB2,KIAA0319,MAGI2,NTM,DMD,CDON,DNM2,SHANK1,DPYSL2,DSCAM,EDNRB,HEYL,SEMA3D,EFNA3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,SEZ6,CDKL3,EYA1,PTK2B,EFEMP1,OLFM1,FGF13,FGFR1,BAIAP2,FOXG1,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,NPTN,STAU2,TBR1,FYN,SYT17,DISC1,ATP8A2,GFAP,GLI2,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,HNRNPK,NEGR1,RBPJ,KNDC1,HES5,BRINP3,ITPKA,L1CAM,MAG,MAP2,MAPT,MBP,MEF2C,MEIS1,CPNE9,MT3,MYCN,NAP1L2,NBL1,NEUROD1,NEUROD2,NF1,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,OMG,OPA1,PAK3,PALM,PAX6,PBX1,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,MED1,PPP3CA,PROX1,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RET,ROBO1,ROBO2,LRRK2,SOX8,SALL1,SEMA6D,DRAXIN,SGK1,PPP1R9A,CPEB3,NLGN1,CDK5RAP3,CCDC88A,TRIM67,SLIT1,CDK5RAP2,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,SOX11,SPP1,KDM4C,RAP1GAP2,SPART,CLASP2,MAPK8IP3,KANK1,SYT1,COBL,SYT4,SEMA4A,CNTN2,ACSL6,VWC2,TCF4,CUX2,ZEB1,TCF12,SYNE1,OBSL1,CRTC1,DICER1,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,TNR,ZMYND8,TTC3,EIF4ENIF1,GORASP1,VLDLR,WNT7A,NDRG4,PLPPR5,LRP8,RGMA,GDPD5,SEMA3B,ITM2C,RTN4,SLC39A12" GO: Biological Process GO:0060322 head development 2.43E-27 2.38E-23 8.83E-25 8.62E-24 273 802 "ABAT,ABR,ARID1A,NDRG2,DSCAML1,NLGN4X,PCDH19,NME5,NR0B1,AK2,MRTFA,OGT,SEMA7A,APAF1,APLP1,APP,SHROOM2,ARRB2,ASCL1,ASPH,CHRD,NCOA1,NUMB,DYNLL1,ATM,ATP2B1,ATP2B2,BBS2,NRP2,BID,CDK5R1,CDK5R2,CACNA1A,CALM1,HAP1,PTBP2,CAST,CBLN1,CBS,INA,SYNGR3,NEURL1,CDC42,CDH2,DCLK1,NOG,NUMBL,GPR37L1,ADGRG1,CHRNB2,SLIT2,LHX2,NRXN1,VAX2,NIPBL,CNTN1,WHRN,AKAP5,SLC4A7,SLC32A1,NCOR1,NCOR2,AATK,CSF1R,CHD5,CNTNAP2,PLXNA4,SLITRK5,CTNND1,CX3CR1,ECE2,SNPH,DBI,DCT,ZEB2,ARNT2,SEC16A,DLX1,TRAPPC9,CDON,DPYSL2,DRD1,SEZ6L2,EDNRA,EFNA2,EGFR,PLEKHA1,EML1,EMX2,EN2,OLIG2,SEZ6,EPHA5,ERBB4,CEND1,EZH1,FABP7,DLC1,SEC24B,FGF13,FGFR1,FGFR3,FOXG1,FOXO3,AFF2,TACC2,AK8,TBR1,NRG3,FYN,GABRA5,SALL3,DISC1,GART,GBX2,PPARGC1A,KIRREL3,TTBK1,GLI2,KDM2B,DCLK2,GNAO1,FUT10,GRIN1,KIF3A,PADI2,HNMT,HNRNPK,HPCA,HTR5A,IGF1,ZIC5,RBPJ,DOCK7,KNDC1,HES5,IL11RA,SLC6A17,KCNA1,KCNC1,KCNC2,KCNK3,STMN1,SMAD1,SMAD9,MAG,MAOB,MAPT,MBP,AFDN,MT3,MDGA1,MYH3,NCAM1,NEFH,NEUROD1,NEUROD2,NF1,NFIX,NKX2-2,NNAT,NODAL,NPY,NRGN,NTRK2,OGDH,OXTR,PAX6,PCDH9,PDGFRA,PFKFB3,SERPINE2,PLP1,PCDH18,MAPKAP1,SCHIP1,SEPT4,MBOAT7,POU3F2,POU3F4,POU6F1,MED1,PPP3CC,MAPK3,HYDIN,PROX1,RELN,PTCH1,PTN,PTPRZ1,PEX5,FAT4,ROGDI,FEZF2,CRTAC1,RFX4,ROBO1,ROBO2,RORB,LRRK2,ATAT1,WLS,SALL1,SEMA6D,DRAXIN,ATXN2,KIF27,TRA2B,ARX,BCAN,SLC1A2,RPH3A,BTBD3,ZNF430,SLC6A11,SLC8A1,RAB3GAP1,SLC8A3,SIRT2,CDK5RAP3,SLIT1,SMARCA4,SMARCC2,CDK5RAP2,FAIM2,MYO16,SOX1,SOX2,SOX3,SSTR1,SSTR2,MAPK8IP3,TTBK2,PLCB1,SYT1,SYT4,TACC1,CNTN2,AGTPBP1,SATB2,TCF7L2,RPGRIP1L,SZT2,DICER1,CDH22,THRA,NR2E1,TNR,RBFOX2,SEZ6L,NR2C2,TSC1,UBE3A,CCDC14,VLDLR,WNT7A,WRN,ZIC1,ZIC2,NDRG4,SPHK2,ZFAND5,CA10,LRP8,GDPD5,PRDM8,SLC17A7,KCNAB1,FZD3,RTN4,KAT6A,IFT88,SLC4A10" GO: Biological Process GO:0060284 regulation of cell development 7.88E-27 7.73E-23 2.76E-24 2.70E-23 317 985 "ACHE,ADCY6,AXIN2,KIDINS220,BEND6,DISP3,LRRC7,SEMA6A,BIN1,SEMA7A,PI16,APBB1,EPB41L5,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,DACT3,BRINP2,NCOA1,NUMB,ADGRB3,BMP7,CDK5R1,SYNJ1,ARHGEF7,RAB29,LDLRAD4,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,SPAG9,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,CDC42,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,CPNE6,NGEF,TJP2,QKI,MAP4K4,CNR1,CNTN1,AKAP6,AKAP5,CLOCK,CRMP1,AATK,CSF1,TENM4,RGS6,FEZ1,SIPA1L1,PLXNA4,RIMS2,CX3CR1,HDAC9,MYADM,HDAC4,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,KIAA0319,MAGI2,NTM,DLX1,DMD,CDON,DNM2,SHANK1,DPYSL2,DSCAM,EDN1,EDNRB,HEYL,SEMA3D,EFNA3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,SEZ6,ERBB4,CDKL3,EYA1,PTK2B,EFEMP1,PRMT5,SLC9B2,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,FOXG1,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,NPTN,DLL3,STAU2,TBR1,NRG3,FYN,NKX6-2,SYT17,DISC1,ATP8A2,GCNT2,GFAP,GLI2,KDM2B,GPER1,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,HAS2,HNRNPK,NEGR1,IGF1,RBPJ,DOCK7,KNDC1,HES5,IL6ST,SCRT2,BRINP3,ITPKA,KIT,L1CAM,LIG4,LIMS1,MAG,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,AFDN,CPNE9,MT3,MYCN,NACA,NAP1L2,NBL1,NEUROD1,NEUROD2,NF1,NFE2L2,NFYA,NKX2-2,NODAL,NOS1,NPR2,NRCAM,NTRK2,NTRK3,OMG,OPA1,PAK3,PALM,PAX6,PBX1,PDE3A,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,MED1,PPP3CA,MAPK9,PROX1,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RET,RFX3,ROBO1,ROBO2,LRRK2,SOX8,AP1AR,SALL1,SEMA6D,ATXN1,DRAXIN,SGK1,PPP1R9A,CPEB3,FUZ,ST6GAL1,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SLIT1,CDK5RAP2,SMARCD3,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,KDM3A,SPP1,KDM4C,RAP1GAP2,SPART,PBLD,CLASP2,MAPK8IP3,PHLDB1,KANK1,SYT1,COBL,SYT4,SEMA4A,TAL1,UNC5D,CNTN2,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,TF,DICER1,SIRT1,TGFBR3,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,TNR,ZMYND8,TTC3,TTPA,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,CRB2,PLPPR5,LRP8,RGMA,GDPD5,SEMA3B,ITM2C,FZD3,RTN4,SLC39A12" GO: Biological Process GO:0000904 cell morphogenesis involved in differentiation 5.09E-26 4.99E-22 1.72E-23 1.68E-22 279 840 "ACHE,ACTN1,DSCAML1,SLITRK1,AXIN2,UNC5A,LRFN2,KIDINS220,SEMA6A,ALCAM,LRFN1,ANK3,SEMA7A,APBB1,APBB2,APC,EPB41L5,ALS2,LRRC4C,APP,SHTN1,SEMA4G,SPTBN4,ARHGDIA,CAPRIN2,DACT3,NUMB,ATP2B2,ADAM15,ADGRB1,ADGRB3,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,LDLRAD4,CACNA1A,KALRN,CAMK2A,CAMK2B,BRSK2,ISPD,CCK,ARHGEF1,SEPT7,CDC42,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,NRXN3,NRXN1,NGEF,VAX2,AKAP5,ZNF385A,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,CTNND2,BOC,MYADM,KIF26A,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DLG4,DNM2,SHANK1,DPYSL2,ABI1,DSCAM,ECM2,WDPCP,ATL1,HEYL,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EIF4G2,ELAVL4,DMTN,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,SEC24B,FER,OLFM1,FGF13,FGFR3,BAIAP2,MAD2L2,FOXG1,FOXF2,SEMA6C,EVL,SEMA4D,PDLIM5,STAU2,TBR1,BRSK1,FYN,CHL1,GAP43,DISC1,ATP8A2,GBX2,GCNT2,NTNG2,GLI2,LOXL3,FERMT2,GRIN1,CIT,RNF165,IL1RAPL1,BVES,LINGO1,HAS2,RBPJ,DOCK7,KNDC1,ITGAV,ITPKA,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,LIMS1,MAG,MAP2,MAP6,MAPT,MATN2,MBP,MEF2C,MT3,MYO7A,NCAM1,NEFH,NODAL,NPTX1,SLC11A2,NRCAM,NTRK2,NTRK3,OMG,OPHN1,PAK3,PAX6,ENPP2,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,FAT3,POU3F2,PPP3CA,PPP3CB,MAPK3,MAPK8,MAPK9,PROX1,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,STRC,RAB3A,FEZF2,RET,ROBO1,ROBO2,TMEM100,LRRK2,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,LRFN5,SGK1,PPP1R9A,ARX,FUZ,NTNG1,ST6GAL1,SLITRK3,NLGN1,SLC1A3,PREX2,BTBD3,LRRC55,RADIL,SLIT1,PALLD,USP33,TNIK,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,PBLD,CLASP2,MAPK8IP3,PHLDB1,KANK1,STXBP1,COBL,SEMA4A,ROBO3,TAL1,UNC5D,CNTN2,CUX2,TCF7L2,CLASP1,SZT2,SYNE1,OBSL1,TEK,TGFBR3,TIAM1,HEY1,BHLHB9,NR2E1,HEY2,PARD3,TNR,RBFOX2,LRTM2,TTC3,UCHL1,GORASP1,FLRT2,VLDLR,WNT7A,ZIC2,CRB2,DPYSL5,LRP8,RGMA,PRDM8,SEMA3B,PCDH15,FZD3,RTN4,JMJD1C,VANGL2,FRMD6,IFT88" GO: Biological Process GO:0007409 axonogenesis 1.68E-25 1.65E-21 5.49E-23 5.36E-22 183 475 "ACHE,DSCAML1,SLITRK1,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,ANK3,SEMA7A,APBB1,APBB2,APC,ALS2,LRRC4C,APP,SHTN1,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,NRP2,BMP7,BMPR1B,CDK5R1,CACNA1A,KALRN,BRSK2,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,NRXN3,NRXN1,VAX2,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,BOC,KIF26A,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DNM2,DPYSL2,DSCAM,ECM2,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EIF4G2,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,TBR1,BRSK1,FYN,CHL1,GAP43,DISC1,ATP8A2,GBX2,NTNG2,GLI2,GRIN1,RNF165,LINGO1,DOCK7,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,MAG,MAP2,MAPT,MATN2,MBP,MT3,NCAM1,NEFH,NPTX1,NRCAM,NTRK2,NTRK3,OMG,OPHN1,PAK3,PAX6,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,POU3F2,PPP3CB,MAPK3,RELN,PTK2,PTPRO,PTPRZ1,RAB3A,FEZF2,RET,ROBO1,ROBO2,S100B,SEMA6D,DRAXIN,LRFN5,ARX,NTNG1,SLITRK3,LRRC55,SLIT1,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,MAPK8IP3,STXBP1,COBL,SEMA4A,ROBO3,UNC5D,CNTN2,SZT2,TIAM1,NR2E1,PARD3,TNR,LRTM2,UCHL1,FLRT2,WNT7A,ZIC2,DPYSL5,RGMA,PRDM8,SEMA3B,FZD3,RTN4,VANGL2" GO: Biological Process GO:0051962 positive regulation of nervous system development 1.47E-24 1.44E-20 4.64E-22 4.53E-21 196 531 "ASIC2,ACHE,SLITRK1,KIDINS220,BEND6,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,SHTN1,CPNE5,ARHGDIA,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,ADGRB1,ADGRB2,ADGRB3,BMP7,SYNJ1,MYRF,MMD2,KALRN,HAP1,CAMK2B,SPAG9,CBLN1,CBFA2T2,NEURL1,NOG,NUMBL,GPR37L1,SLIT2,CPNE6,NRXN3,NRXN1,QKI,CNR1,CNTN1,AKAP5,CSF1,TENM4,RGS6,FEZ1,SLITRK5,RIMS2,CX3CR1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,DMD,CDON,SHANK1,DSCAM,HEYL,EIF4G1,EIF4G2,ELAVL4,OLIG2,SEZ6,EPHB1,CDKL3,PTK2B,PRMT5,FGFR1,BAIAP2,FOXG1,SEMA4D,SYT3,NPTN,DLL3,STAU2,FYN,NKX6-2,SYT17,DISC1,ATP8A2,WASF3,GFAP,GLI2,GPER1,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,HNRNPK,NEGR1,IGF1,IL6ST,BRINP3,LRRTM3,LRRTM1,ITPKA,KIT,L1CAM,LRRC4B,LIG4,MAG,MAPT,MEF2C,CPNE9,NAP1L2,NBL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,OPA1,OXTR,PAK3,PALM,PAX6,ENPP2,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,LRRN3,PROX1,RELN,PTK2,PTN,PTPRD,PTPRZ1,FEZF2,RET,ROBO1,ROBO2,SYNDIG1,SOX8,SALL1,ATXN1,LRRTM4,SGK1,PPP1R9A,CPEB3,SLITRK3,NLGN1,CLSTN1,TRIM67,SMARCD3,RIMS1,SOX2,SOX10,SOX11,KDM4C,CLSTN2,MAPK8IP3,SYT1,COBL,SYT4,ADGRL3,ACSL6,VWC2,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,TF,DICER1,SIRT1,TIAM1,BHLHB9,PARD3,LRRC24,ZMYND8,LRTM2,FLRT2,FLRT1,VLDLR,WNT7A,XRCC4,NDRG4,PLPPR5,LRP8,RGMA,GDPD5,FZD3,RTN4,CBLN2" GO: Biological Process GO:0061564 axon development 2.33E-24 2.29E-20 7.15E-22 6.98E-21 191 514 "ACHE,DSCAML1,SLITRK1,UNC5A,LRFN2,SEMA6A,ALCAM,LRFN1,ANK3,SEMA7A,APBB1,APBB2,APC,ALS2,LRRC4C,APP,SHTN1,SEMA4G,SPTBN4,ARHGDIA,NUMB,ADGRB1,NRP2,BMP7,BMPR1B,CDK5R1,CACNA1A,DDR1,KALRN,BRSK2,ISPD,CCK,ARHGEF1,SEPT7,CDH2,DCLK1,LGI1,NOG,NUMBL,CHN1,CHRNB2,SLIT2,LHX2,NRXN3,NRXN1,VAX2,CNR1,CRMP1,AATK,CSF1R,FEZ2,FEZ1,SIPA1L1,PLXNA4,SLITRK5,BOC,KIF26A,IST1,DBN1,DCC,ZEB2,PLPPR4,SNAP91,DNM2,DPYSL2,DSCAM,ECM2,ATL1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EIF4G2,EPHA5,EPHB1,ERBB2,CDKL3,ETV1,NRN1,TUBB3,OLFM1,FGF13,FGFR3,BAIAP2,FOXG1,SEMA6C,EVL,SEMA4D,TBR1,BRSK1,FYN,CHL1,GAP43,DISC1,ATP8A2,GBX2,NTNG2,GLI2,GRIN1,RNF165,LINGO1,DOCK7,JAK2,KIF5A,KIF5C,STXBP5,L1CAM,LAMA2,STMN1,MAG,MAP2,MAPT,MATN2,MBP,MT3,MTR,NCAM1,NEFM,NEFH,NPTX1,NRCAM,NTRK2,NTRK3,OMG,OPHN1,PAK3,PAX6,NLGN3,SSH1,SEMA5B,PLP1,PLXNB1,PLXNB3,POU3F2,PPP3CB,MAPK3,RELN,PTK2,PTPRO,PTPRZ1,RAB3A,FEZF2,CRTAC1,RET,ROBO1,ROBO2,RXRA,S100B,SEMA6D,DRAXIN,LRFN5,ARX,NTNG1,SLITRK3,LRRC55,SLIT1,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,SPART,NFASC,CLASP2,MAPK8IP3,STXBP1,COBL,SEMA4A,ROBO3,UNC5D,CNTN2,SZT2,TIAM1,NR2E1,PARD3,TNR,LRTM2,UCHL1,FLRT2,WNT7A,ZIC2,DPYSL5,RGMA,PRDM8,SEMA3B,FZD3,RTN4,VANGL2" GO: Biological Process GO:0048167 regulation of synaptic plasticity 7.95E-24 7.80E-20 2.36E-21 2.31E-20 89 169 "ABHD6,ADORA1,ADORA2A,AGT,PPFIA3,ATP2B2,CALB1,CAMK2A,CAMK2B,SHISA7,CD38,NEURL1,DGKI,SLC24A2,PICK1,SIPA1L1,CTNND2,CX3CR1,DBI,DBN1,DLG4,DRD1,PTK2B,FGF14,BAIAP2,NPTN,STAU2,JPH4,CPLX2,GFAP,GRIA1,GRIK1,GRIK2,GRIN1,NR3C1,GRM5,PTPN5,HNRNPK,SHISA6,MYLK2,LRRTM1,ITPKA,KCNB1,KCNJ10,KIT,MAPT,MEF2C,MYO6,NCAM1,NEUROD2,NF1,NOS1,NRGN,NTRK2,NLGN3,SERPINE2,PPP3CB,PRKCZ,RELN,PTN,RAB3A,RASGRF1,RASGRF2,S100B,PPP1R9A,CPEB3,BCAN,NLGN1,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,SORCS3,RIMS1,SNAP25,SNCA,IQSEC2,NCDN,STAU1,STXBP1,ARC,SYP,CNTN2,CRTC1,NR2E1,TNR,VGF,NETO1,JPH3" GO: Biological Process GO:0042391 regulation of membrane potential 3.09E-23 3.03E-19 8.91E-21 8.70E-20 155 391 "ABAT,KCNH8,ASIC2,ASIC1,ACTN2,ADORA1,ADORA2A,ADRB2,NLGN4X,AGT,ANK2,ANK3,CNIH2,CNTNAP1,SHTN1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,HCN2,MTMR2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CAMK2D,CCK,DGKI,CHRNA4,CHRNB2,NRXN1,CNGA3,CNR1,AKAP7,AKAP6,SLC25A27,RIMS4,RIMS2,NOS1AP,RIMS3,DBN1,CNIH3,DLG4,DMD,DMPK,SHANK1,DPP6,DRD1,EDN1,SEZ6,KCNMB2,CACNG2,PTK2B,RACK1,FGF12,FGF14,FHL1,OGA,GABRB3,GLRB,KCNMB4,GPER1,RAPGEF4,GRIA1,GRIK1,GRIK2,GRIK3,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,BVES,KCNA1,KCNA2,KCNB1,KCNC2,KCND2,KCND3,KCNH1,KCNH2,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,MEF2C,CTNNA3,NPPA,NRCAM,HCN1,GPR88,P2RX7,KCNK10,NLGN3,NALCN,FXYD1,PPP3CA,PRKCZ,SLC26A11,RELN,PXK,PTN,PPP2R3C,PID1,SLC25A36,MYH14,LRRK2,KCNIP2,KCNIP1,STX1B,ATXN1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,PPP1R9A,NLGN1,SLC1A6,SLC8A1,RAB3GAP1,IGSF9B,RIMS1,SNCA,SCN3B,SPART,STOX1,STX1A,TAC1,POPDC3,TACR1,CUX2,TPCN2,CRTC1,ZMYND8,NTSR2,KCNE5,WNT7A,KCNK12,SLC26A10,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0050806 positive regulation of synaptic transmission 5.31E-22 5.21E-18 1.49E-19 1.45E-18 81 153 "ABAT,ADORA1,ADORA2A,ARRB2,SYNJ1,CACNA1B,HAP1,CAMK2B,CCKBR,LGI1,CHRNB2,NRXN1,SLC24A2,RIMS2,CX3CR1,DBI,DBN1,DLG4,DNM1,SHANK1,DRD1,EGFR,ERBB4,PTK2B,NPTN,GFAP,GLUL,GPER1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,PTPN5,HNRNPK,LRRTM1,LAMA2,NAT8L,NF1,NOS1,NRGN,NTRK2,OXTR,NLGN3,SERPINE2,PRKCZ,RELN,PTK2,PTN,RAB3A,RASGRF2,STX1B,S100B,PPP1R9A,NLGN1,CLSTN1,SLC1A3,SLC8A2,RAB3GAP1,SLC8A3,SHANK2,IGSF9B,RIMS1,SNAP25,SNCA,IQSEC2,CLSTN2,STAU1,STX1A,ARC,SYT1,TAC1,TACR1,CUX2,CRTC1,NR2E1,TNR,WNT7A,NETO2,NETO1" GO: Biological Process GO:0006836 neurotransmitter transport 6.88E-22 6.74E-18 1.87E-19 1.83E-18 100 212 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CADPS,ATP1A2,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,SYT6,DGKI,NRXN3,NRXN1,NRXN2,PNKD,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SNAP91,SV2B,SV2A,DRD1,EDN3,SYT15,STX2,SYT3,BRSK1,GABRA2,GAD1,GAD2,SYT17,CPLX2,CPLX1,GFAP,GLUL,KCNMB4,GPM6B,GPER1,PCLO,GRIK5,GRM8,HRH3,ICA1,SLC6A17,C2CD4C,KCNJ10,SYTL4,NAT8L,SYT9,MEF2C,NF1,NOS1,NTRK2,P2RX7,SYTL2,PTPRN2,RAB3A,SLC6A15,LRRK2,STX1B,PPP1R9A,NLGN1,SLC1A3,RPH3A,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYN2,SYT1,SYT4,SYT5,WNT7A,TRIM9,SLC38A1,SLC17A7,SLC17A6" GO: Biological Process GO:0010975 regulation of neuron projection development 1.02E-21 9.98E-18 2.70E-19 2.63E-18 179 492 "ACHE,ADCY6,KIDINS220,LRRC7,SEMA6A,SEMA7A,APBB1,LRRC4C,SHTN1,CPNE5,SEMA4G,ARHGDIA,CAPRIN2,NUMB,ADGRB3,BMP7,CDK5R1,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,ARHGEF1,CBFA2T2,NEURL1,CDH2,NUMBL,CHN1,CHRNB2,SLIT2,CPNE6,NGEF,QKI,MAP4K4,CNR1,CNTN1,AKAP5,CRMP1,AATK,FEZ1,SIPA1L1,PLXNA4,RIMS2,IST1,DBN1,DCC,ZEB2,KIAA0319,MAGI2,NTM,DMD,DNM2,SHANK1,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,ELAVL4,SEZ6,CDKL3,PTK2B,EFEMP1,OLFM1,FGF13,FGFR1,BAIAP2,SEMA6C,SEMA4D,SYT3,PDLIM5,NPTN,STAU2,TBR1,FYN,SYT17,DISC1,ATP8A2,GFAP,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,PTPN5,IL1RAPL1,LINGO1,HNRNPK,NEGR1,RBPJ,KNDC1,ITPKA,L1CAM,MAG,MAP2,MAPT,MBP,MEF2C,CPNE9,MT3,NFE2L2,NRCAM,NTRK2,NTRK3,OMG,OPA1,PAK3,PALM,PAX6,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,PPP3CA,RELN,KLK6,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,FEZF2,RET,ROBO1,ROBO2,LRRK2,SEMA6D,DRAXIN,SGK1,PPP1R9A,CPEB3,NLGN1,CCDC88A,TRIM67,SLIT1,RIMS1,SNAP25,TNIK,SPP1,RAP1GAP2,SPART,CLASP2,KANK1,SYT1,COBL,SYT4,SEMA4A,CNTN2,ACSL6,CUX2,SYNE1,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,NR2E1,TNR,ZMYND8,GORASP1,VLDLR,WNT7A,NDRG4,PLPPR5,LRP8,RGMA,SEMA3B,ITM2C,RTN4,SLC39A12" GO: Biological Process GO:0031344 regulation of cell projection organization 1.58E-21 1.55E-17 4.08E-19 3.98E-18 221 657 "ACHE,ADCY6,ERMN,KIDINS220,TBC1D14,LRRC7,SEMA6A,SEMA7A,APBB1,APC,LRRC4C,SHTN1,CPNE5,SEMA4G,ARHGDIA,CAPRIN2,NUMB,ADGRB3,BMP7,CDK5R1,ARHGEF7,RAB29,CACNA1A,KALRN,HAP1,CAMK2B,ARHGEF1,CBFA2T2,NEURL1,SEPT7,CDC42,CDH2,EVI5L,NUMBL,CHN1,CHRNB2,SLIT2,CPNE6,NRXN1,NGEF,QKI,MAP4K4,CCDC151,CNR1,CNTN1,AKAP5,CRMP1,AATK,FEZ1,SIPA1L1,PLXNA4,PPP1R16B,RIMS2,USP6NL,ARHGAP24,HDAC4,TBC1D5,IST1,DBN1,DCC,ZEB2,KIAA0319,MAGI2,NTM,DMD,DNM2,SHANK1,DPYSL2,DSCAM,USH1C,WDPCP,SEMA3D,PLXNC1,EIF4G2,TENM1,ELAVL4,DMTN,SEZ6,CDKL3,SH3YL1,TBC1D16,PTK2B,EFEMP1,FER,OLFM1,FGF13,FGFR1,BAIAP2,SEMA6C,EVL,SEMA4D,SYT3,PDLIM5,NPTN,STAU2,TBR1,FYN,NCKAP1,GAP43,SYT17,DISC1,SEPT9,ATP8A2,GFAP,GPM6A,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,CIT,PTPN5,IL1RAPL1,LINGO1,HNRNPK,NEGR1,HSP90AA1,RBPJ,KNDC1,ITPKA,KIT,L1CAM,MAG,MAP2,MAP4,MAPT,MBP,MEF2C,CPNE9,MT3,NFE2L2,NRCAM,NTRK2,NTRK3,ODF2,OMG,OPA1,P2RX7,PAK3,PALM,PAX6,ENPP2,NLGN3,SERPINE2,SSH1,SEMA5B,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,PPP3CA,RELN,KLK6,BCAS3,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,CEP97,RAP1GAP,FEZF2,RDX,RET,KCTD17,ROBO1,ROBO2,LRRK2,SEMA6D,DRAXIN,SGK1,PPP1R9A,CPEB3,FUZ,NLGN1,CCDC88A,TRIM67,SLIT1,RIMS1,SNAP25,TNIK,SPP1,RAP1GAP2,SPART,CLASP2,TTBK2,KANK1,SYT1,COBL,SYT4,SEMA4A,CNTN2,ACSL6,CUX2,SYNE1,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,NR2E1,TNR,ZMYND8,GORASP1,VLDLR,TBC1D15,WNT7A,NDRG4,PLPPR5,LRP8,RGMA,EVI5,SEMA3B,ITM2C,RTN4,SLC39A12,IFT88" GO: Biological Process GO:0001505 regulation of neurotransmitter levels 1.64E-21 1.61E-17 4.13E-19 4.04E-18 100 214 "ABAT,SYN3,ASIC1,ACHE,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CADPS,ATP1A2,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,SYT6,DGKI,NRXN3,NRXN1,NRXN2,PNKD,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SNAP91,DRD1,EDN3,SYT15,STX2,SYT3,BRSK1,GABRA2,GAD1,GAD2,SYT17,CPLX2,CPLX1,GFAP,GLUL,KCNMB4,GPM6B,GPER1,PCLO,GRIK5,GRM8,HRH3,HNMT,ICA1,C2CD4C,KCNJ10,SYTL4,NAT8L,MAOB,SYT9,MEF2C,NF1,NOS1,NTRK2,P2RX7,PAH,PDE1B,SYTL2,PTPRN2,RAB3A,PRIMA1,LRRK2,STX1B,PPP1R9A,NLGN1,SLC1A3,RPH3A,SLC6A9,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYN2,SYT1,SYT4,SYT5,AGTPBP1,WNT7A,TRIM9,SLC38A1,SLC17A7,SLC17A6" GO: Biological Process GO:0051049 regulation of transport 6.15E-21 6.03E-17 1.51E-18 1.47E-17 522 1975 "TTYH1,ABAT,KCNH8,ABR,ASIC2,ASIC1,ACHE,ACTN2,ADCY5,ADCYAP1R1,ADD1,AXIN2,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,TBC1D14,OSBPL8,DISP3,PLA2G6,C1QTNF1,C1QTNF3,SYT13,DOC2A,BIN1,OGT,DPP10,ANK2,ANK3,CNIH2,APBB1,KCNAB2,GPAM,APOC1,APOC2,MADD,CASK,SPTBN4,ARNTL,ARRB1,RGS20,ARRB2,CADPS,PDE8B,ASPH,DACT3,DYNLL1,ATP1A1,ATP1A2,ATP1B3,ATP2A2,ATP2B2,RIPK1,BARD1,HCN2,BID,BMP7,CDK5R1,SYNJ1,ARHGEF7,MTMR2,CACNA1I,CACNA1G,C5,RAB29,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,SYT6,BRSK2,CCK,CCKBR,USP6,RGN,SCARB1,SYNGR3,CD38,CDC42,CDH2,KCNAB3,EVI5L,CACNA2D2,CBARP,CHGA,CHRM1,CHRNA4,RAB3C,CHRNB2,CLCN3,CLCN4,NRXN1,STOML1,MAP4K4,RAB26,CNR1,PICK1,CNTN1,AKAP7,AKAP6,CABP1,SLC25A27,AKAP5,BAG4,MYRIP,PNKD,CLOCK,CRHBP,CRY2,NCOR1,CLIP3,ABCG1,SNCAIP,CSF1R,RIMS4,CALY,APPL1,RIMS2,RUBCN,USP6NL,NOS1AP,CYBB,GAPVD1,TCAF1,SNPH,ZFYVE16,TBC1D5,RIMS3,DAPK1,DBI,SIRPA,DBN1,DNAJC6,B3GAT3,CNIH3,C2CD2L,MAGI2,POM121,SNAP91,SGSM2,G3BP2,RABGAP1L,DLG4,DMD,DNM1,DMPK,DNM2,SHANK1,DOCK2,DPP6,DPYSL2,DRD1,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,SYT15,RASGRP1,SIDT2,CACNG7,SH3GLB1,EGFR,TENM1,TNK2,DMTN,EPHA5,ERBB2,ERBB4,APC2,DNAJC27,TLR7,SIRPB1,REEP2,CACNG3,CACNG2,TBC1D16,ACSL4,PTK2B,PRAM1,ATP8A1,RACK1,FCGR1A,SEC24B,FER,FGF12,FGF14,FGFR1,FGR,PRKAG2,FHL1,MEX3B,ANKFY1,SGIP1,SYT3,SORBS1,ZBED3,HVCN1,TRIM16,PRELID3A,SARAF,OGA,GABBR1,CAB39,AHCYL1,JPH4,GALR1,SYT17,ATP8A2,INPP5K,CPLX2,CPLX1,GCK,ARFIP1,GDF9,GFAP,PCDH17,PPARGC1A,GLUL,OS9,KCNMB4,GNAO1,GNAS,GPM6B,STON1,MCHR1,GPR26,GPER1,PCLO,RAPGEF4,GRB10,GRIK1,GRIK5,GRIN1,GRIN2D,NR3C1,GRM7,GRM8,KIF3A,PTPN5,IL1RAPL1,BVES,PACSIN2,HRH3,NCKAP1L,HMGB1,HMGCR,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,SMAP1,HTR2A,ICA1,MYLK2,IGF1,SCIN,LRRTM1,ITGAV,C2CD4C,JAK2,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNMA1,KCNN2,KCNN3,KCNQ2,KCNQ3,IPO5,STXBP5,SYTL4,NAT8L,MAOB,MAPT,LYPLAL1,SYT9,MDFI,MEF2C,SCAMP5,MXI1,MYBPC1,MYO5A,MYO6,MYT1,FXYD7,HNRNPM,NCAM1,NEFH,NELL2,NEUROD1,NF1,NFE2L2,NNAT,NODAL,NOS1,NPPA,CLEC9A,HCN1,NTRK2,NUCB1,NUCB2,TBC1D25,OGG1,OPHN1,OPRL1,OXTR,P2RX7,P2RY1,KCNK10,PAX6,PDE1C,PDE2A,PDE3B,PDE4B,PDE4D,PIRT,PDPK1,BEST3,PFKFB2,ZDHHC8,NLGN3,SERPINE2,NALCN,PIK3C2A,PIK3R1,PKD1,PLCD1,FXYD1,PLTP,PACSIN1,PPARA,MED1,PPM1B,PPP3CA,PPP3CB,PPP3CC,NKAIN4,RANBP3L,PKIA,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,RELN,BCAS3,SYTL2,PTAFR,PTCH1,PTK2,PXK,PTX3,NKAIN1,RAB3A,RAB5B,PID1,SH3TC2,RAP1GAP,RASGRF1,RASGRF2,RDX,RFX3,RNASEL,FBXW7,SGSM1,LRRK2,LGR4,KCNIP3,WLS,KCNIP2,KCNIP1,STX1B,ATXN2,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCP2,SMPD3,ELMOD1,IL17RB,SGK1,SCG5,PPP1R9A,SH3GL2,MYO18A,SYBU,NLGN1,ABLIM3,SLC1A2,RPH3A,EPN2,SLC6A1,SLC8A1,RAB3GAP1,SLC11A1,NAPB,LGI3,ARFGAP1,SLN,RIMS1,SNAP25,SNCA,LMBRD1,SCN3B,SOX11,PBLD,CLASP2,NKAIN2,STX1A,KANK1,SULF2,STXBP1,SYT11,MLC1,ABCC8,PLCB1,SYN1,ARC,SYT1,SYT4,SYT5,TAC1,TACR1,MTCL1,WWC1,FBXW11,ACSL6,TCF7L2,TPCN2,CLASP1,AZIN2,SYNE1,TEK,ATP13A2,TF,SIRT1,SPX,THRA,TIAM1,TLR4,LRRC8A,PARD3,TP53BP2,ZNF384,TRH,STXBP4,TRPC1,TRPC3,TRPM2,KCNE5,TSC2,TUB,SGK3,CADM1,BEST1,TBC1D15,VSNL1,WIPF1,P2RY12,KCNK12,XPO1,ZIC1,TRIM9,NDRG4,REEP1,SLC30A3,WNK1,MFF,EVI5,HPS4,KCNAB1,WNK3,WNK2,C12orf4,GOPC,RTN4,NUP214,NLRP3,AAAS,NETO2,JPH3" GO: Biological Process GO:0007611 learning or memory 7.75E-21 7.60E-17 1.85E-18 1.81E-17 116 271 "ASIC1,ADCY8,SLC12A5,FZD9,ADRA1B,ADRB2,NLGN4X,PLA2G6,AMPH,APBB1,APP,PDE8B,ATP1A2,ATP1A3,ADGRB3,BCHE,SYNJ1,CACNA1E,CALB1,KALRN,DGKI,NOG,CHRNB2,NRXN3,NRXN1,NRXN2,SLC24A2,CNR1,ZNF385A,CRHBP,CNTNAP2,CTNND2,CX3CR1,DBI,DLG4,SHANK1,DRD1,RCAN1,EGFR,ABI2,ELAVL4,RCAN2,ATP8A1,PPP1R1B,FGF13,AFF2,NPTN,TBR1,FYN,GABRA5,JPH4,C1QL1,GRIA1,GRIN1,GRM5,GRM7,HRH3,HMGCR,HTR2A,IGF1,KCNK2,KIT,SHC3,MEF2C,MEIS2,NCAM1,NEUROD2,NF1,NPTX2,SLC11A2,NRGN,NTRK2,OXTR,KCNK10,PDE1B,TMOD2,NLGN3,PPP3CB,PRKAR1B,PRKCG,PRKCZ,RELN,PTN,PTPRZ1,RASGRF1,S100B,ATXN1,NLGN4Y,SGK1,CPEB3,SLC6A1,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,PLCB1,ARC,TAC1,TACR1,DDHD2,CNTN2,CUX2,CRTC1,THRA,BHLHB9,TNR,VLDLR,NDRG4,SLC17A7,KCNAB1,EPM2A,PAK5,AAAS,NETO1,JPH3" GO: Biological Process GO:0035249 "synaptic transmission, glutamatergic" 9.27E-21 9.09E-17 2.16E-18 2.11E-17 54 83 "ADORA1,ADORA2A,ADRB2,PLA2G6,CNIH2,ALS2,ATP1A2,CACNA1A,CACNB4,KALRN,CCKBR,DGKI,CDH8,CLCN3,NRXN1,CNR1,CNIH3,DRD1,EGFR,PTK2B,GLUL,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK5,GRIN1,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,SHC3,MEF2C,NF1,NTRK2,OPHN1,OXTR,NLGN3,SERPINE2,RELN,LRRK2,NLGN1,RAB3GAP1,SHANK2,NAPB,IQSEC2,SYT1,TNR,SLC17A7" GO: Biological Process GO:0050890 cognition 1.07E-20 1.05E-16 2.45E-18 2.39E-17 125 303 "ASIC1,ADCY8,SLC12A5,FZD9,ADORA1,PTCHD1,ADRA1B,ADRB2,NLGN4X,PLA2G6,AMPH,APBB1,APP,PDE8B,ATP1A2,ATP1A3,ADGRB3,BCHE,SYNJ1,CACNA1E,CALB1,KALRN,DGKI,NOG,CHRM1,CHRNA4,CHRNB2,NRXN3,NRXN1,NRXN2,SLC24A2,NIPBL,CNR1,ZNF385A,CRHBP,CNTNAP2,CTNND2,CX3CR1,DBI,DLG4,SHANK1,DRD1,RCAN1,EGFR,ABI2,ELAVL4,RCAN2,ATP8A1,PPP1R1B,FGF13,AFF2,NPTN,TBR1,FYN,GABRA5,CHL1,JPH4,C1QL1,GNAS,GRIA1,GRIN1,GRM5,GRM7,HRH3,HMGCR,HTR2A,IGF1,KCNK2,KIT,GPR155,SHC3,MEF2C,MEIS2,NCAM1,NEUROD2,NF1,NPTX2,SLC11A2,NRGN,NTRK2,OXTR,KCNK10,PDE1B,TMOD2,NLGN3,JAKMIP1,PPP3CB,PRKAR1B,PRKCG,PRKCZ,RELN,PTN,PTPRZ1,RASGRF1,S100B,ATXN1,NLGN4Y,SGK1,CPEB3,SLC6A1,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,PLCB1,ARC,TAC1,TACR1,DDHD2,CNTN2,CUX2,CRTC1,THRA,BHLHB9,TNR,VLDLR,NDRG4,SLC17A7,KCNAB1,EPM2A,PAK5,AAAS,NETO1,JPH3" GO: Biological Process GO:0007270 neuron-neuron synaptic transmission 2.22E-20 2.18E-16 4.95E-18 4.84E-17 79 154 "SYN3,ADORA1,ADORA2A,ADRB2,PLA2G6,CNIH2,ALS2,ARRB2,ATP1A2,CACNA1A,CACNB4,KALRN,HAP1,CCKBR,DGKI,CDH8,DLGAP2,CHRNB2,CLCN3,NRXN1,CNR1,PNKD,CRHBP,DBI,CNIH3,DNM1,DRD1,EGFR,ERBB4,PTK2B,GABRA1,GABRB3,GABRG2,GLRB,GLUL,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK5,GRIN1,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,NAT8L,SHC3,MEF2C,NF1,NTRK2,OPHN1,OXTR,TMOD2,NLGN3,SERPINE2,PLCL1,RELN,LRRK2,NLGN1,SLC6A1,SLC6A9,RAB3GAP1,SHANK2,NAPB,SNCA,KIF1B,IQSEC2,STXBP1,SYT1,TAC1,TACR1,TNR,RASD2,SLC17A7" GO: Biological Process GO:0030900 forebrain development 7.51E-20 7.37E-16 1.64E-17 1.60E-16 152 407 "ARID1A,NR0B1,MRTFA,OGT,SEMA7A,APAF1,APLP1,APP,ASCL1,CHRD,NCOA1,NUMB,BBS2,NRP2,CDK5R1,CDK5R2,HAP1,CDH2,DCLK1,NOG,NUMBL,ADGRG1,CHRNB2,SLIT2,LHX2,VAX2,AKAP5,SLC32A1,NCOR1,NCOR2,CSF1R,CHD5,CNTNAP2,PLXNA4,SLITRK5,CX3CR1,DBI,DCT,ZEB2,DLX1,TRAPPC9,CDON,DPYSL2,DRD1,EFNA2,EGFR,EMX2,OLIG2,EPHA5,ERBB4,EZH1,FABP7,DLC1,FGF13,FGFR1,FGFR3,FOXG1,TACC2,TBR1,NRG3,FYN,SALL3,DISC1,GART,GBX2,PPARGC1A,KIRREL3,GLI2,KDM2B,DCLK2,GNAO1,FUT10,GRIN1,KIF3A,HNRNPK,HTR5A,ZIC5,RBPJ,DOCK7,HES5,KCNA1,KCNC1,KCNC2,AFDN,MDGA1,NCAM1,NEFH,NEUROD1,NF1,NPY,NRGN,NTRK2,OGDH,OXTR,PAX6,PCDH9,MBOAT7,POU3F2,POU3F4,PROX1,RELN,PTN,PTPRZ1,PEX5,FAT4,FEZF2,CRTAC1,RFX4,ROBO1,ROBO2,LRRK2,ATAT1,SALL1,DRAXIN,TRA2B,ARX,BCAN,SLC1A2,BTBD3,SLC8A1,RAB3GAP1,SLC8A3,SLIT1,SMARCA4,SMARCC2,SOX1,SOX2,SOX3,SSTR1,SSTR2,MAPK8IP3,TTBK2,PLCB1,TACC1,CNTN2,AGTPBP1,SATB2,TCF7L2,RPGRIP1L,SZT2,DICER1,NR2E1,TNR,TSC1,VLDLR,WNT7A,LRP8,GDPD5,PRDM8,RTN4,IFT88,SLC4A10" GO: Biological Process GO:0022604 regulation of cell morphogenesis 1.04E-19 1.02E-15 2.21E-17 2.16E-16 204 609 "ACHE,FMNL2,AXIN2,CDC7,ERMN,TBC1D14,SEMA6A,SEMA7A,FGD2,ANXA7,EPB41L5,GAS7,LRRC4C,SHTN1,CPNE5,SEMA4G,ARHGDIA,CAPRIN2,DACT3,NUMB,ADGRB3,CDK5R1,ARHGEF7,LDLRAD4,CFAP410,CACNA1A,KALRN,HAP1,CAMK2B,FMNL3,ARHGEF1,SEPT7,CDC42,CDH2,ZMYM4,EVI5L,NUMBL,CHN1,CHRNB2,TAOK2,SLIT2,CPNE6,NGEF,CCDC151,AKAP5,AATK,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,PLXNA4,RIMS2,USP6NL,MYADM,TBC1D5,IST1,DAPK3,DBN1,DCC,ZEB2,DNM2,DPYSL2,DSCAM,WDPCP,SEMA3D,PLXNC1,EIF4G2,PLEKHO1,EPB41,EPB41L2,DMTN,EPS8,CDKL3,TBC1D16,PTK2B,DLC1,OLFM1,FGF13,BAIAP2,MAD2L2,FGR,CAMSAP1,SEMA6C,SEMA4D,SYT3,PDLIM5,STAU2,TBR1,FYN,SYT17,DISC1,SEPT9,WASF3,GCNT2,TTBK1,FERMT2,GRIN1,CIT,KIF3A,IL1RAPL1,BVES,LINGO1,HAS2,HNRNPK,KNDC1,ITGA7,ITPKA,KIT,L1CAM,LIMS1,MAG,MAP2,MAP4,MAPT,MBP,MKLN1,CPNE9,MT3,NRCAM,NTRK2,NTRK3,ODF2,OMG,PAK3,PALM,ENPP2,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,SH3KBP1,POU3F2,PPP3CA,MAPK9,FITM2,RELN,QRICH1,PTK2,PTN,PTPRD,PTPRO,PTPRZ1,CEP97,FEZF2,RDX,RET,KCTD17,MYH14,ROBO1,ROBO2,LRRK2,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,SGK1,PPP1R9A,FUZ,ST6GAL1,NLGN1,SLIT1,RIMS1,TNIK,SPP1,SPART,PBLD,CLASP2,EPB41L3,LARP4,TTBK2,PHLDB1,KANK1,FGD4,ARC,SYT1,SYT4,SEMA4A,CNTN2,CUX2,TCF7L2,CLASP1,SYNE1,OBSL1,TGFBR3,TIAM1,BHLHB9,NR2E1,TNR,TPM1,TTC3,GORASP1,TBC1D15,WIPF1,WNT7A,CRB2,LRP8,RGMA,EVI5,SEMA3B,WIPF2,RTN4,IFT88" GO: Biological Process GO:0007626 locomotory behavior 3.60E-19 3.53E-15 7.51E-17 7.34E-16 102 234 "ABAT,ADCY5,ADORA2A,ADRA1B,APBA2,ALS2,APP,SPTBN4,ARRB2,ASTN1,ATP1A2,ATP1A3,ATP2B2,CACNA1A,CACNA1B,CACNA1E,CACNB4,CALB1,USP2,CIART,CHRNA4,CHRNB2,CLCN3,ZNF385A,PUM1,DBN1,DLG4,DNM1,DRD1,DSCAM,RCAN1,SEZ6L2,EFNB3,ELAVL4,RCAN2,SEZ6,EPS8,CEND1,FGF12,FGF14,GAA,CHL1,GAD1,C1QL1,HPGDS,GLRB,GNAO1,GPR37,GRIN1,GRIN2D,GRM1,GRM5,NEGR1,LRRTM1,KCND2,KCNJ10,KCNMA1,LSAMP,MAPT,MEIS1,ADAM22,MYO5A,MYO6,NOVA1,GPR88,OPRL1,PDE1B,PENK,ZDHHC8,PPP3CB,MAPK10,RELN,OXR1,FEZF2,FIGN,LRRK2,ATXN1,SCN8A,PREX2,SNAP25,SNCA,ANKFN1,NPAS3,VPS13A,DDHD2,TAL1,CNTN2,ADGRL3,AGTPBP1,TMOD1,TNR,SEZ6L,RASD2,TRH,TSC1,UCHL1,LGI4,ZIC1,PCDH15,NAV2,PAK5,SLC4A10" GO: Biological Process GO:0050769 positive regulation of neurogenesis 1.82E-18 1.79E-14 3.61E-16 3.53E-15 164 465 "ACHE,KIDINS220,BEND6,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,SHTN1,CPNE5,ARHGDIA,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,BMP7,SYNJ1,MMD2,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NEURL1,NOG,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,CSF1,TENM4,RGS6,FEZ1,RIMS2,CX3CR1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,DMD,CDON,SHANK1,DSCAM,HEYL,EIF4G1,EIF4G2,ELAVL4,OLIG2,SEZ6,CDKL3,PTK2B,PRMT5,FGFR1,BAIAP2,FOXG1,SEMA4D,SYT3,NPTN,DLL3,STAU2,FYN,NKX6-2,SYT17,DISC1,ATP8A2,GFAP,GLI2,GPER1,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,HNRNPK,NEGR1,IL6ST,BRINP3,ITPKA,KIT,L1CAM,LIG4,MAG,MAPT,MEF2C,CPNE9,NAP1L2,NBL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,OPA1,PAK3,PALM,PAX6,ENPP2,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,PROX1,RELN,PTK2,PTN,PTPRD,PTPRZ1,FEZF2,RET,ROBO1,ROBO2,SOX8,SALL1,ATXN1,SGK1,PPP1R9A,CPEB3,NLGN1,TRIM67,SMARCD3,RIMS1,SOX2,SOX10,SOX11,KDM4C,MAPK8IP3,SYT1,COBL,SYT4,ACSL6,VWC2,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,TF,DICER1,SIRT1,TIAM1,BHLHB9,ZMYND8,VLDLR,XRCC4,NDRG4,PLPPR5,LRP8,RGMA,GDPD5,FZD3,RTN4" GO: Biological Process GO:0007269 neurotransmitter secretion 1.84E-18 1.81E-14 3.61E-16 3.53E-15 79 163 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,SYT6,DGKI,NRXN3,NRXN1,NRXN2,PNKD,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SNAP91,EDN3,SYT15,STX2,SYT3,BRSK1,GAD1,GAD2,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,HRH3,ICA1,C2CD4C,SYTL4,SYT9,MEF2C,NF1,NTRK2,P2RX7,SYTL2,PTPRN2,RAB3A,LRRK2,STX1B,PPP1R9A,NLGN1,RPH3A,SLC6A9,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYN2,SYT1,SYT4,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0099643 signal release from synapse 1.84E-18 1.81E-14 3.61E-16 3.53E-15 79 163 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,SYT6,DGKI,NRXN3,NRXN1,NRXN2,PNKD,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SNAP91,EDN3,SYT15,STX2,SYT3,BRSK1,GAD1,GAD2,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,HRH3,ICA1,C2CD4C,SYTL4,SYT9,MEF2C,NF1,NTRK2,P2RX7,SYTL2,PTPRN2,RAB3A,LRRK2,STX1B,PPP1R9A,NLGN1,RPH3A,SLC6A9,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYN2,SYT1,SYT4,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0007215 glutamate receptor signaling pathway 3.63E-18 3.56E-14 6.98E-16 6.82E-15 48 75 "CNIH2,APP,ATP1A3,CDK5R1,CAMK2A,NRXN1,HOMER3,CRHBP,DAPK1,CNIH3,DLG4,GRIN3A,SHANK1,CACNG7,CACNG3,CACNG2,PTK2B,PPARGC1A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNB1,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1,CPEB4,SSTR1,PLCB1,ARC,NETO2" GO: Biological Process GO:0099531 presynaptic process involved in chemical synaptic transmission 9.45E-18 9.27E-14 1.78E-15 1.74E-14 81 173 "SYN3,ASIC1,ADORA2A,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CADPS,ATP2A2,SYNJ1,BAIAP3,CACNA1A,CACNA1B,CAMK2A,SYT6,DGKI,NRXN3,NRXN1,NRXN2,PNKD,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SNAP91,DRD1,EDN3,SYT15,STX2,SYT3,BRSK1,GAD1,GAD2,SYT17,CPLX2,CPLX1,KCNMB4,GPER1,PCLO,GRIK5,GRM8,HRH3,ICA1,C2CD4C,SYTL4,NAT8L,SYT9,MEF2C,NF1,NTRK2,P2RX7,SYTL2,PTPRN2,RAB3A,LRRK2,STX1B,PPP1R9A,NLGN1,RPH3A,SLC6A9,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYN2,SYT1,SYT4,SYT5,WNT7A,TRIM9" GO: Biological Process GO:0007416 synapse assembly 1.05E-17 1.03E-13 1.95E-15 1.91E-14 73 148 "ASIC2,ACHE,SLITRK1,NLGN4X,APP,ADGRB1,ADGRB2,ADGRB3,BSN,CACNA1A,CBLN1,CDH2,CHRNB2,NRXN3,NRXN1,NRXN2,SLITRK5,SPOCK2,MAGI2,DRD1,DSCAM,EPHB1,PDLIM5,STAU2,DNER,KIRREL3,GPM6A,PCLO,GRIN1,IL1RAPL1,LRRTM3,LRRTM1,LRRC4B,MEF2C,DBNL,MDGA1,MYO6,NRCAM,NTRK2,NTRK3,OXTR,NLGN3,SDK2,LRRN3,RELN,PTK2,PTPRD,ROBO2,SYNDIG1,LRRTM4,NLGN4Y,PPP1R9A,SLITRK3,NLGN1,CLSTN1,SHANK2,SLIT1,CLSTN2,ADGRL3,CUX2,PCDHB10,PCDHB9,PCDHB6,PCDHB4,PCDHB3,BHLHB9,LRRC24,LRTM2,CADM1,FLRT2,FLRT1,WNT7A,CBLN2" GO: Biological Process GO:0060078 regulation of postsynaptic membrane potential 4.11E-17 4.03E-13 7.46E-15 7.28E-14 56 100 "ABAT,ASIC2,ADORA1,ADORA2A,ADRB2,NLGN4X,HCN2,MTMR2,DGKI,CHRNA4,NRXN1,RIMS2,DBN1,DLG4,DMPK,SHANK1,SEZ6,PTK2B,FGF14,GABRB3,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,GRIN2D,MEF2C,HCN1,NLGN3,PPP3CA,PRKCZ,RELN,LRRK2,STX1B,ATXN1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,PPP1R9A,NLGN1,RAB3GAP1,IGSF9B,RIMS1,SNCA,SCN3B,STX1A,CUX2,ZMYND8,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0007612 learning 8.38E-17 8.22E-13 1.49E-14 1.46E-13 76 162 "ASIC1,SLC12A5,ADRA1B,ADRB2,NLGN4X,AMPH,APBB1,APP,PDE8B,ATP1A2,ATP1A3,ADGRB3,BCHE,SYNJ1,CACNA1E,DGKI,NOG,CHRNB2,NRXN3,NRXN1,NRXN2,SLC24A2,CNTNAP2,CTNND2,DLG4,SHANK1,DRD1,ELAVL4,ATP8A1,PPP1R1B,FGF13,NPTN,TBR1,FYN,GABRA5,JPH4,C1QL1,GRIN1,GRM5,GRM7,HRH3,HMGCR,KIT,MEIS2,NEUROD2,NF1,NPTX2,NRGN,NTRK2,PDE1B,NLGN3,PPP3CB,RELN,PTN,PTPRZ1,ATXN1,NLGN4Y,SGK1,SLC6A1,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,ARC,TAC1,TACR1,DDHD2,CNTN2,TNR,NDRG4,EPM2A,PAK5,AAAS,NETO1,JPH3" GO: Biological Process GO:0006811 ion transport 1.60E-16 1.57E-12 2.80E-14 2.74E-13 427 1627 "TTYH1,ABAT,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,ADCYAP1R1,ADD2,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRB2,SLC24A4,SLC44A5,AGT,OSBPL8,PLA2G6,ABCD2,UNC79,KCNT1,DPP10,ANK1,ANK2,ANK3,PPFIA4,PPFIA2,CNIH2,PPFIA1,KCNAB2,APOC1,CACHD1,APOC2,PPFIA3,SHROOM2,AQP4,AQP6,SLC7A14,CASK,SPTBN4,ARRB2,ASPH,NCOA1,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,RIPK1,HCN2,BTK,CACNA1I,CACNA1G,NIPA1,CA4,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SLC25A14,CAPN3,CLDN10,CCK,CCKBR,SLC5A11,RGN,SLC16A4,P2RX6,SCARB1,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRM1,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,NRXN1,SLC24A2,STOML1,CLTC,CNGA3,CNR1,CNTN1,AKAP7,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,COX4I1,CP,CRHBP,CRY2,SLC32A1,NCOR1,ABCG1,PITPNM3,PNPLA8,NOS1AP,CYBB,TCAF1,DAPK1,DBI,PITPNC1,HEPH,CNIH3,KLHL3,DLG3,DLG4,GRIN3A,DMD,DMPK,DNM2,SHANK1,SLC12A6,DPP6,DPYSL2,DRD1,ABCC5,ABCC9,EDN1,EDN3,EDNRA,SGK2,CNNM1,CACNG7,CALCRL,MFSD10,KCNMB2,SLC43A2,NCALD,CACNG3,CACNG2,ACSL4,PTK2B,ATP8A1,TOMM40L,SLC9B2,FGF12,FGF14,FGFR1,PRKAG2,FHL1,ATP5PD,IP6K2,PCYOX1,ATP13A4,SLC37A3,FOLR2,TMEM175,HVCN1,ATP6V1H,ATP2C1,PRELID3A,SARAF,OGA,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CAB39,AHCYL1,JPH4,ATP8A2,INPP5K,STARD10,CPLX1,GCK,PPARGC1A,GLRB,GLS,KCNMB4,GNAO1,GNAS,GPM6A,GPM6B,MCHR1,GPER1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,NR3C1,GRM2,GRM7,IL1RAPL1,MFSD2A,SLC2A6,HBA1,HRH3,TNFAIP8L3,HTR2A,IGF1,SLC6A17,ITGAV,SLC35G1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,SFXN5,NAT8L,MAOB,AQP11,MEF2C,MT3,MTTP,MYO5A,MYO6,FXYD7,FXYD6,NF1,SLCO1C1,NOS1,NPY,NPPA,SLC11A2,HCN1,NTRK2,OPRL1,P2RX7,P2RY1,KCNK10,PDE2A,PDE4B,PDE4D,PIRT,PDPK1,SLC10A4,BEST3,ABCB1,NLGN3,SERPINE2,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,SLC36A4,PPARA,PPP3CA,NKAIN4,PRKAB2,PRKCB,MAPK9,SLC26A11,RELN,CNNM2,SLC22A23,PTAFR,PXK,NKAIN1,RAB3A,RASGRF1,RASGRF2,SLC6A15,ATP8B4,KCNIP3,KCNIP2,KCNIP1,RXRA,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,SCP2,SMPD3,ASIC4,SLC30A10,SEC14L1,RASA3,SGK1,NLGN1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A1,LRRC55,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,RAB3GAP1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SLN,RIMS1,SNAP25,SNCA,UNC80,SCN3B,ATP10B,NKAIN2,STX1A,STXBP1,MLC1,ABCC8,ARHGEF9,PLCB1,ARC,SYT1,SLC37A2,ATP11A,ANO4,ACSL6,TPCN2,AZIN2,SLC19A3,ATP13A2,TF,SPX,SLC44A1,LRRC8A,TRH,TRPC1,TRPC3,TRPM2,KCNE5,CA14,TSC1,ANO5,SGK3,UBC,SLC35A4,PITPNB,BEST1,P2RY12,SLC13A3,KCNK12,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,WNK1,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,RTN4,TMEM63C,SLC39A12,NETO2,SLC4A10,JPH3" GO: Biological Process GO:0010720 positive regulation of cell development 3.10E-16 3.04E-12 5.33E-14 5.21E-13 185 572 "ACHE,AXIN2,KIDINS220,BEND6,LRRC7,SEMA6A,BIN1,SEMA7A,APBB1,EPB41L5,SHTN1,CPNE5,ARHGDIA,ASCL1,ASPA,CAPRIN2,BRINP2,NCOA1,NUMB,BMP7,SYNJ1,ARHGEF7,MMD2,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NEURL1,CDC42,NOG,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP6,AKAP5,CSF1,TENM4,RGS6,FEZ1,RIMS2,CX3CR1,MYADM,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,DMD,CDON,DNM2,SHANK1,DSCAM,EDN1,HEYL,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,SEZ6,CDKL3,PTK2B,PRMT5,SLC9B2,OLFM1,FGFR1,BAIAP2,FOXG1,SEMA4D,SYT3,NPTN,DLL3,STAU2,FYN,NKX6-2,SYT17,DISC1,ATP8A2,GCNT2,GFAP,GLI2,KDM2B,GPER1,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,HAS2,HNRNPK,NEGR1,IL6ST,BRINP3,ITPKA,KIT,L1CAM,LIG4,LIMS1,MAG,MAPT,MEF2C,CPNE9,NAP1L2,NBL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,OPA1,PAK3,PALM,PAX6,PDE3A,ENPP2,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,MAPK9,PROX1,RELN,PTK2,PTN,PTPRD,PTPRZ1,FEZF2,RET,RFX3,ROBO1,ROBO2,SOX8,SALL1,ATXN1,SGK1,PPP1R9A,CPEB3,NLGN1,SIRT2,TRIM67,SMARCD3,RIMS1,SOX2,SOX10,SOX11,KDM4C,MAPK8IP3,SYT1,COBL,SYT4,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,OBSL1,CRTC1,TF,DICER1,SIRT1,TIAM1,BHLHB9,ZMYND8,VLDLR,XRCC4,NDRG4,CRB2,PLPPR5,LRP8,RGMA,GDPD5,FZD3,RTN4" GO: Biological Process GO:0051961 negative regulation of nervous system development 4.35E-16 4.26E-12 7.35E-14 7.18E-13 117 309 "ADCY6,DISP3,SEMA6A,SEMA7A,APBB1,APP,SEMA4G,ARHGDIA,ASCL1,CHRD,BMP7,CDK5R1,MTMR2,RAB29,ARHGEF1,CBFA2T2,ARHGEF2,NOG,GPR37L1,ADGRG1,SLIT2,NGEF,MAP4K4,CRMP1,AATK,BRINP1,DCC,KIAA0319,NTM,DLX1,EDNRB,SEMA3D,OLIG2,SEZ6,ERBB4,CDKL3,CEND1,EFEMP1,OLFM1,FGF13,FGFR3,FOXG1,SEMA6C,FOXO3,SEMA4D,DLL3,NRG3,NKX6-2,GFAP,STMN2,CIT,SOX21,LINGO1,HNRNPK,RBPJ,HES5,MAG,MBD1,MBP,MEIS1,MT3,MDGA1,MYCN,NEUROD2,NF1,NKX2-2,NTRK3,OMG,PAX6,PBX1,GPR173,NLGN3,SEMA5B,PMP22,FAT3,MED1,PPP3CA,PRKACB,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RFX4,ROBO2,SOX8,SEMA6D,DRAXIN,NLGN1,SIRT2,SLIT1,CDK5RAP2,IFT122,SOX2,SOX3,SOX11,SPP1,RAP1GAP2,SPART,KANK1,SEMA4A,CNTN2,DICER1,GPR161,HEY1,NR2E1,TNR,TTC3,EIF4ENIF1,GORASP1,WNT7A,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0043269 regulation of ion transport 4.97E-16 4.87E-12 8.26E-14 8.07E-13 208 669 "TTYH1,ABAT,KCNH8,ASIC2,ACTN2,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AGT,PLA2G6,DPP10,ANK2,ANK3,CNIH2,KCNAB2,CASK,SPTBN4,ARRB2,ASPH,ATP1A1,ATP1A2,ATP1B3,ATP2B2,RIPK1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,CCK,RGN,KCNAB3,CACNA2D2,CBARP,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,NRXN1,STOML1,CNR1,CNTN1,AKAP7,AKAP6,AKAP5,CRHBP,CRY2,NCOR1,NOS1AP,CYBB,TCAF1,DAPK1,DBI,CNIH3,DLG4,DMD,DMPK,DNM2,SHANK1,DPP6,DPYSL2,DRD1,EDN1,EDN3,EDNRA,SGK2,CACNG7,CACNG3,CACNG2,ACSL4,PTK2B,ATP8A1,FGF12,FGF14,FHL1,HVCN1,SARAF,OGA,GABBR1,CAB39,AHCYL1,JPH4,ATP8A2,INPP5K,GCK,PPARGC1A,GNAO1,GNAS,GPM6B,MCHR1,GPER1,GRIK1,GRIN1,GRIN2D,NR3C1,GRM7,HRH3,HTR2A,IGF1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNMA1,KCNN2,KCNQ2,KCNQ3,NAT8L,MAOB,MEF2C,MYO5A,FXYD7,NOS1,NPPA,HCN1,OPRL1,P2RX7,P2RY1,KCNK10,PDE4B,PDE4D,PIRT,PDPK1,BEST3,NLGN3,SERPINE2,NALCN,PIK3C2A,FXYD1,NKAIN4,PRKCB,MAPK9,RELN,PTAFR,PXK,NKAIN1,RASGRF1,RASGRF2,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SGK1,NLGN1,SLC6A1,SLC8A1,RAB3GAP1,SLN,SNCA,SCN3B,NKAIN2,ABCC8,PLCB1,ARC,ACSL6,TPCN2,LRRC8A,TRH,TRPC1,TRPC3,KCNE5,SGK3,BEST1,P2RY12,KCNK12,WNK1,KCNAB1,WNK3,WNK2,RTN4,NETO2,JPH3" GO: Biological Process GO:0035637 multicellular organismal signaling 6.93E-16 6.80E-12 1.13E-13 1.11E-12 85 197 "AGT,ANK2,ANK3,CNTNAP1,PRX,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CACNA2D2,CNTNAP2,DMPK,DPP6,DRD1,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,AHCYL1,KCNMB4,GPER1,RAPGEF4,GRIA1,GRIK2,GRM7,KCNA1,KCNA2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,KCNMA1,KCNQ2,CTNNA3,FXYD7,FXYD6,NOS1,NPPA,NPR2,NRCAM,GPR88,PDE4D,FXYD1,MYH14,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A2,SLC8A1,SLC8A3,SCN3B,NFASC,TNR,TRPC1,KCNE5" GO: Biological Process GO:0016358 dendrite development 8.23E-16 8.07E-12 1.32E-13 1.29E-12 97 239 "ACHE,SLC12A5,KIDINS220,APP,CAPRIN2,NUMB,ADGRB3,BMP7,CDK5R1,CACNA1A,KALRN,CAMK2A,CAMK2B,NEURL1,SEPT7,DCLK1,NUMBL,CHRNB2,NGEF,AKAP5,SIPA1L1,SLITRK5,CTNND2,DBN1,DCC,KIAA0319,DLG4,GRIN3A,SHANK1,ABI1,DSCAM,ABI2,EIF4G2,ELAVL4,SEZ6,EPHA5,EPHB1,CDKL3,ACSL4,BAIAP2,SEMA4D,PDLIM5,STAU2,FYN,DISC1,RAPGEF4,GRIN1,NR3C1,CIT,IL1RAPL1,HNRNPK,KNDC1,ITPKA,MAP2,MAP6,MATN2,MEF2C,GIT1,MYO6,SLC11A2,NTRK2,OPA1,PAK3,PALM,NLGN3,PACSIN1,FAT3,PPP3CA,MAPK8,RELN,PTPRD,PTPRZ1,FEZF2,ROBO1,LRRK2,SGK1,PPP1R9A,CPEB3,NLGN1,PREX2,BTBD3,TNIK,COBL,CUX2,SYNE1,OBSL1,CRTC1,TIAM1,BHLHB9,NR2E1,RBFOX2,ZMYND8,GORASP1,FLRT1,VLDLR,WNT7A,LRP8" GO: Biological Process GO:0042063 gliogenesis 9.98E-16 9.79E-12 1.56E-13 1.52E-12 108 279 "ADORA2A,AGT,BIN1,PRX,ASCL1,ASPA,CDK5R1,SYNJ1,ARHGEF7,MYRF,CDK5R2,IL33,CDH2,NOG,GPR37L1,ADGRG1,CLU,QKI,PICK1,CSF1,TENM4,ARHGEF10,VCAN,DBI,DLX1,DMD,OLIG1,MED12,DRD1,EGFR,OLIG2,ERBB2,ERCC2,PTK2B,EFEMP1,PRMT5,FGFR3,FOXG1,DLL3,NKX6-2,GAP43,DISC1,WASF3,DNER,GFAP,GSN,LINGO1,IGF1,HES5,IL6ST,ITGAM,KCNJ10,LAMA2,MAG,MATN2,MBD1,AFDN,ADAM22,MT3,MYCN,NF1,NFIX,NKX2-2,NTRK2,NTRK3,OMG,P2RY1,PAX6,ENPP2,PENK,NLGN3,SERPINE2,PLP1,MBOAT7,FA2H,POU3F2,MAPK3,RELN,PTK2,PTN,PTPRZ1,SH3TC2,SOX8,S100B,ATXN1,SOX6,SLC8A3,SIRT2,SMARCA4,SOX2,SOX5,ZCCHC24,SOX10,SOX11,TAL1,CNTN2,TCF7L2,TF,DICER1,TIAM1,TLR4,NR2E1,PARD3,P2RY12,LGI4,LRP8,PRDM8,RTN4" GO: Biological Process GO:0051966 "regulation of synaptic transmission, glutamatergic" 1.00E-15 9.83E-12 1.56E-13 1.52E-12 39 59 "ADORA1,ADORA2A,PLA2G6,ATP1A2,KALRN,CCKBR,DGKI,NRXN1,CNR1,DRD1,EGFR,PTK2B,GLUL,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,MEF2C,NTRK2,OPHN1,OXTR,NLGN3,SERPINE2,RELN,LRRK2,NLGN1,RAB3GAP1,SHANK2,IQSEC2,SYT1,TNR" GO: Biological Process GO:2000026 regulation of multicellular organismal development 1.27E-15 1.24E-11 1.94E-13 1.90E-12 480 1893 "ASIC2,ACHE,SLITRK1,ADCY6,ADD1,AXIN2,ADRB2,KIDINS220,BEND6,AP2A1,AP2A2,AGT,DISP3,LRRC7,SEMA6A,AMH,BIN1,OGT,SEMA7A,PI16,APBB1,APC,EPB41L5,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARNTL,ARRB2,ASCL1,ASPA,CAPRIN2,DACT3,PTCH2,BRINP2,CHRD,NCOA1,NUMB,RIPK1,ADGRB1,ADGRB2,ADGRB3,PROM1,BMP7,BMPR1B,CDK5R1,SYNJ1,BTK,MTMR2,C1QC,C5,RAB29,MYRF,LDLRAD4,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,CBLN1,KRIT1,USP2,RGN,CD86,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,SEPT7,CDC42,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,CHRNB2,SLIT2,CPNE6,NRXN3,NRXN1,CLTC,NGEF,FBXO7,TJP2,QKI,MAP4K4,NIPBL,CNR1,CNTN1,AKAP6,AKAP5,MAGED1,CLOCK,CRMP1,AATK,CSF1,TENM4,CSF1R,RGS6,CSF3R,FEZ1,SIPA1L1,SOCS5,PLXNA4,SLITRK5,PPP1R16B,PHF14,CTH,RIMS2,CX3CR1,CYBB,BOC,HDAC9,MYADM,HDAC4,RASSF2,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,KIAA0319,MAGI2,PARD6A,NTM,DLX1,DMD,MED12,NR1D2,CDON,DNM2,SHANK1,DPYSL2,DSCAM,WDPCP,EDN1,EDNRA,EDNRB,HEYL,RASGRP1,SEMA3D,EFNA3,CELSR3,EGR3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,LRRC17,SEZ6,EPHB1,ERBB2,ERBB4,CDKL3,CEND1,EYA1,F3,PTK2B,EFEMP1,RACK1,PRMT5,SEC24B,SLC9B2,KIAA1109,FGF1,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,FOXG1,AGAP2,SEMA6C,FOXO3,SEMA4D,FLT1,SYT3,PDLIM5,TRIM16,NPTN,DLL3,STAU2,TBR1,NRG3,FYN,MEGF10,NKX6-2,ERAP1,SYT17,DISC1,ATP8A2,WASF3,GCNT2,MSTN,GDF9,GFAP,USP19,GLI2,GNAS,LILRB4,GPM6B,GPER1,RAPGEF4,STMN2,RAPGEF1,GRIN1,NR3C1,GRM5,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,ATOH8,IRAK3,NCKAP1L,HMGB1,HMGCR,HNRNPK,NEGR1,HSP90AA1,SMAP1,IGF1,NKD1,RBPJ,DOCK7,KNDC1,SCIN,HES5,IL6ST,SCRT2,IL12A,BRINP3,LRRTM3,LRRTM1,ITPKA,ITPKB,JAK1,KCNK2,KIT,L1CAM,LAMA2,LRRC4B,LIG4,LIMS1,LMO2,SMAD1,MAG,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,MEIS2,KITLG,MITF,AFDN,CPNE9,MT3,RSPO2,MDGA1,MYCN,MYH6,NACA,NAP1L2,NBL1,NCAM1,NELL1,NEUROD1,NEUROD2,NF1,NFE2L2,NKX2-2,NODAL,NOS1,NRCAM,NTRK2,NTRK3,DDR2,OMG,OPA1,OXTR,P2RX7,PAK3,PALM,PAX6,PBX1,PDCD2,PDE3B,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PIK3R1,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,FAT3,POU3F2,MED1,LRRN3,PPP3CA,PRKACB,PRKCB,PRKCZ,MAPK7,MAPK8,PROX1,RELN,KLK6,PSMA6,LAMA1,PSMD13,PTCH1,PTHLH,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,PPP2R3C,FAT4,RAP1GAP,FEZF2,RET,RFX3,RFX4,RNH1,ROBO1,ROBO2,TMEM100,FBXW7,LRRK2,LGR4,SYNDIG1,SOX8,RXRA,RXRG,S100B,SALL1,SEMA6D,ATXN1,DRAXIN,LRRTM4,FNIP1,SOX6,SGK1,PPP1R9A,CPEB3,FUZ,SLITRK3,NLGN1,ANKRD6,CLSTN1,LIMS2,SLC8A1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,BTBD7,SLIT1,CDK5RAP2,SMARCD3,IFT122,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,SOX15,SPP1,KDM4C,RAP1GAP2,SPART,PBLD,CLASP2,CLSTN2,MESP1,STOX1,MAPK8IP3,PHLDB1,KANK1,SULF2,PLCB1,SYT1,COBL,SYT4,SEMA4A,TAL1,UNC5D,CNTN2,ADGRL3,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,TEK,TF,DICER1,SIRT1,ZFPM2,GPR161,TGFBR3,HHIP,THBS4,TIAM1,TIE1,HEY1,TLL2,BHLHB9,TLR4,NR2E1,HEY2,PARD3,TNR,RBFOX2,IL34,NR2C2,LRRC24,TRPS1,ZMYND8,LRTM2,TTC3,UBC,EIF4ENIF1,AMOT,GORASP1,FLRT2,FLRT1,VLDLR,P2RY12,NSD2,WNT7A,XRCC4,ZIC2,NDRG4,CRB2,CELF4,ZBTB16,PLPPR5,LRP8,RGMA,GDPD5,ADAMTS9,TMEM178A,SEMA3B,ITM2C,FZD3,RTN4,NLRP3,VANGL2,SLC39A12,IFT88,CBLN2" GO: Biological Process GO:0043087 regulation of GTPase activity 1.53E-15 1.50E-11 2.31E-13 2.26E-12 211 688 "RALGAPA1,ABR,ACTN2,PLEKHG5,AXIN2,TBC1D14,BCAR3,ARHGAP20,AMPH,BIN1,FGD2,PKP4,ALS2,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ARRB2,DOCK11,ADGRB3,RGS11,RGS9,FGF17,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,RGN,ARHGEF1,DGKI,ARHGEF2,ARHGAP33,EVI5L,CCPG1,RCBTB2,CHM,CHN1,CHN2,CHRM4,ARHGAP22,SLIT2,NGEF,ARHGEF6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ELMO1,TIAM2,SRGAP3,SGSM2,RABGAP1L,DLG4,CPEB2,DOCK2,RASGRP1,FAM13A,EGFR,RASA4,EIF5,TNK2,RGS17,RASGRP2,EPHA5,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,PSD2,ARFGAP2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,GNAO1,GNAS,ADAP1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,BVES,FICD,ARHGAP19,NCKAP1L,ARHGAP36,AGFG1,SMAP1,DOCK7,KNDC1,INPP5B,JAK1,JAK2,KIT,IPO5,STXBP5,LIMS1,ARHGAP12,SHC3,KITLG,AFDN,GIT1,MYO9A,NCAM1,NF1,NTRK2,NTRK3,TBC1D25,OCRL,OPHN1,PDGFRA,PLXNB1,PLXNB3,RASGEF1B,PSD,BCAS3,PTK2,PTPRN2,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RDX,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,SGSM1,LRRK2,RTKN,SBF1,FNIP1,ELMOD1,RASA3,ITSN1,ASAP3,DOCK10,PREX2,RAB3GAP1,ARHGEF40,ARFGAP1,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,ST5,RGL1,FGD4,ARHGEF9,PLCB1,MLST8,MCF2L,DNMBP,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,TIAM1,TRIO,TSC1,TSC2,AMOT,VAV1,VAV2,TBC1D15,P2RY12,RICTOR,EVI5,DOCK8,SPATA13" GO: Biological Process GO:0021537 telencephalon development 2.22E-15 2.18E-11 3.30E-13 3.22E-12 102 260 "SEMA7A,ASCL1,NCOA1,NUMB,BBS2,NRP2,CDK5R1,CDK5R2,CDH2,NUMBL,ADGRG1,SLIT2,LHX2,AKAP5,SLC32A1,NCOR2,CSF1R,CNTNAP2,PLXNA4,SLITRK5,CX3CR1,DBI,ZEB2,DLX1,TRAPPC9,CDON,DPYSL2,DRD1,EFNA2,EGFR,EMX2,EPHA5,ERBB4,EZH1,FGF13,FGFR1,FOXG1,TACC2,NRG3,SALL3,DISC1,GART,KIRREL3,KDM2B,DCLK2,FUT10,GRIN1,KIF3A,HNRNPK,HTR5A,HES5,KCNA1,AFDN,MDGA1,NEFH,NEUROD1,NF1,NPY,NRGN,NTRK2,OGDH,OXTR,PAX6,MBOAT7,POU3F2,PROX1,RELN,PTPRZ1,PEX5,FAT4,FEZF2,CRTAC1,RFX4,ROBO1,ROBO2,LRRK2,ATAT1,SALL1,TRA2B,ARX,BCAN,SLC1A2,BTBD3,SLC8A1,SLC8A3,SLIT1,SOX2,PLCB1,TACC1,CNTN2,AGTPBP1,RPGRIP1L,SZT2,DICER1,NR2E1,TNR,TSC1,VLDLR,LRP8,PRDM8,RTN4,IFT88" GO: Biological Process GO:0051094 positive regulation of developmental process 2.78E-15 2.73E-11 4.07E-13 3.98E-12 355 1323 "ASIC2,ACHE,SLITRK1,ADD1,AXIN2,ADRB2,KIDINS220,BEND6,AGT,LRRC7,SEMA6A,BIN1,OGT,SEMA7A,APBB1,APC,EPB41L5,GPAM,SHTN1,CPNE5,SPTBN4,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,PTCH2,BRINP2,NCOA1,NUMB,RIPK1,ADGRB1,ADGRB2,ADGRB3,BBS2,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,BTK,C5,MYRF,MMD2,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,CBLN1,USP2,CD86,CBFA2T2,NEURL1,SEPT7,CDC42,CDH2,NOG,NUMBL,CACNA2D2,GPR37L1,SLIT2,CPNE6,NRXN3,NRXN1,CLU,QKI,NIPBL,CNR1,CNTN1,AKAP6,AKAP5,MAGED1,ZNF385A,CSF1,TENM4,CSF1R,RGS6,FEZ1,SOCS5,SLITRK5,PPP1R16B,CTH,RIMS2,CX3CR1,CYBB,BOC,HDAC9,MYADM,MAML1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,BLOC1S6,CCDC3,DMD,CDON,DNM2,SHANK1,DSCAM,DNM1L,FIS1,EDN1,EDN3,EDNRA,HEYL,RASGRP1,EGR3,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,SEZ6,EPHB1,ERBB4,CDKL3,F3,PTK2B,RACK1,PRMT5,SLC9B2,FGF1,OLFM1,FGFR1,FGFR3,BAIAP2,SUCO,FOXG1,AGAP2,FOXO3,SEMA4D,FLT1,SYT3,TRIM16,NPTN,CELF1,DLL3,STAU2,FYN,NKX6-2,ERAP1,SYT17,DISC1,SEPT9,ATP8A2,WASF3,GCNT2,GFAP,GHR,PPARGC1A,GLI2,KDM2B,GNAS,GPM6B,GPER1,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,ATOH8,WIF1,IRAK3,HAS2,NCKAP1L,HMGB1,HMGCR,HNRNPK,NEGR1,HSP90AA1,SMAP1,HTR2A,IFI16,IGF1,RBPJ,SCIN,IL6R,IL6ST,IL12A,BRINP3,INSM1,LRRTM3,LRRTM1,ITPKA,ITPKB,JAK1,JAK2,KIT,L1CAM,LRRC4B,LIG4,LIMS1,SMAD1,SMAD9,MAG,MAPT,MEF2C,KITLG,CPNE9,MSR1,NACA,NAP1L2,NBL1,NCAM1,NELL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NODAL,NRCAM,NTRK2,NTRK3,DDR2,OPA1,OXTR,P2RX7,PAK3,PALM,PAX6,PDCD2,PDE3A,ENPP2,NLGN3,SERPINE2,PIK3R1,PLXNB1,PLXNB3,PACSIN1,POU3F2,MED1,LRRN3,PRKCB,PRKCZ,MAPK8,MAPK9,PROX1,RELN,GDPD2,PTCH1,PTK2,PTN,PTPRD,PTPRZ1,PEX5,PPP2R3C,FEZF2,RET,RFX3,KCTD17,ROBO1,ROBO2,TMEM100,LGR4,SYNDIG1,SOX8,SALL1,MAPK12,ATXN1,LRRTM4,SOX6,SGK1,PPP1R9A,ARX,CPEB3,FUZ,SLITRK3,NLGN1,CLSTN1,SLC8A1,SIRT2,TRIM67,EPC1,SMARCA4,SMARCD3,RIMS1,SOX2,SOX5,SOX10,SOX11,SOX15,ZHX3,KDM4C,LMO3,CLASP2,CLSTN2,MESP1,STOX1,MAPK8IP3,TTBK2,PHLDB1,PLCB1,SYT1,COBL,SYT4,DDHD2,TAL1,ADGRL3,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,CLASP1,OBSL1,CRTC1,TEK,TF,DICER1,SIRT1,ZFPM2,THRA,TIAM1,HEY1,DDHD1,BHLHB9,NR2E1,HEY2,PARD3,IL34,NR2C2,LRRC24,ZMYND8,FNDC5,LRTM2,AMOT,FLRT2,FLRT1,VLDLR,NSD2,WNT7A,XRCC4,ZIC2,NDRG4,CRB2,ZBTB16,PLPPR5,MFF,LRP8,RGMA,GDPD5,ADAMTS9,HPS4,FZD3,RTN4,NLRP3,CBLN2" GO: Biological Process GO:0048813 dendrite morphogenesis 3.89E-15 3.81E-11 5.60E-13 5.47E-12 67 142 "ACHE,KIDINS220,CAPRIN2,NUMB,ADGRB3,CDK5R1,CACNA1A,KALRN,CAMK2A,CAMK2B,SEPT7,DCLK1,NUMBL,CHRNB2,NGEF,AKAP5,SIPA1L1,SLITRK5,CTNND2,DBN1,DLG4,SHANK1,ABI1,DSCAM,ELAVL4,EPHA5,EPHB1,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,FYN,GRIN1,CIT,IL1RAPL1,KNDC1,ITPKA,MAP2,MAP6,SLC11A2,PAK3,NLGN3,PPP3CA,MAPK8,RELN,PTPRD,PTPRZ1,ROBO1,LRRK2,SGK1,PPP1R9A,NLGN1,PREX2,BTBD3,TNIK,CUX2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,RBFOX2,GORASP1,VLDLR,WNT7A,LRP8" GO: Biological Process GO:0045595 regulation of cell differentiation 4.15E-15 4.07E-11 5.91E-13 5.77E-12 436 1699 "ACHE,ADCY6,AXIN2,KIDINS220,BEND6,AP2A2,AGT,NR0B1,DISP3,LRRC7,SEMA6A,LTBP4,BIN1,OGT,SEMA7A,PI16,APBB1,APC,EPB41L5,LRRC4C,APP,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,DACT3,PTCH2,BRINP2,CHRD,NCOA1,NUMB,RIPK1,ADGRB3,CFLAR,PROM1,BMP7,BMPR1B,CDK5R1,SYNJ1,ARHGEF7,BTK,C1QC,RAB29,LDLRAD4,MMD2,CACNA1A,KALRN,HAP1,CAMK2B,CAPN3,SPAG9,RUNX1T1,CD86,ARHGEF1,CBFA2T2,NEURL1,ARHGEF2,CDC42,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,CHN1,PLEKHB1,CHRNB2,SLIT2,CPNE6,CLU,NGEF,FBXO7,TJP2,QKI,MAP4K4,CNR1,CNTN1,AKAP6,AKAP5,ZNF385A,CLOCK,CRMP1,NCOR2,ABCG1,AATK,CSF1,TENM4,CSF1R,RGS6,CSF3R,FEZ1,SIPA1L1,CHD5,SOCS5,PLXNA4,CMTM5,CTH,RIMS2,CX3CR1,BOC,HDAC9,MYADM,HDAC4,RASSF2,MAML1,IST1,SPOCK2,BRINP1,DBN1,DCC,DCT,ZEB2,KIAA0319,MAGI2,BLOC1S6,NTM,CCDC3,DLX1,DMD,DMPK,NR1D2,CDON,DNM2,SHANK1,FAM57B,DPYSL2,DSCAM,EDN1,EDN3,EDNRB,HEYL,RASGRP1,SEMA3D,EFNA3,EGR3,PLXNC1,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,LRRC17,SEZ6,ERBB2,ERBB4,APC2,CDKL3,ADGRV1,EYA1,PTK2B,EFEMP1,PRMT5,SLC9B2,KIAA1109,OLFM1,FGF13,FGFR1,FGFR3,BAIAP2,MAD2L2,SUCO,FOXG1,SEMA6C,FOXO3,SEMA4D,FLT1,SYT3,PDLIM5,TRIM16,NPTN,DLL3,STAU2,TBR1,NRG3,FYN,MEGF10,NKX6-2,SYT17,DISC1,ATP8A2,GCNT2,MSTN,GFAP,GLI2,KDM2B,GNAS,LILRB4,GPER1,RAPGEF4,STMN2,RAPGEF1,C1QL4,PLPP7,GRIN1,NR3C1,GRM5,CIT,PTPN5,IL1RAPL1,SOX21,LINGO1,ATOH8,WIF1,HAS2,NCKAP1L,HMGB1,HNRNPK,NEGR1,HSP90AA1,SMAP1,HTR2A,IFI16,IGF1,RBPJ,DOCK7,KNDC1,SCIN,HES5,IL6R,IL6ST,SCRT2,IL12A,BRINP3,INSM1,ITGAV,ITPKA,ITPKB,JAK2,KIT,L1CAM,LIG4,LIMS1,LMO2,SMAD1,SMAD9,MAG,MAP2,MAPT,MBD1,MBP,MEF2C,MEIS1,MEIS2,KITLG,MITF,AFDN,CPNE9,MSR1,MT3,MYCN,NACA,NAP1L2,NBL1,NELL1,NEUROD1,NEUROD2,NF1,NFE2L2,NFYA,NKX2-2,NODAL,NOS1,NPR2,NRCAM,NTRK2,NTRK3,DDR2,NUCB2,OMG,OPA1,PAK3,PALM,PAX6,PBX1,PDCD2,PDE3A,PDGFRA,ENPP2,GPR173,NLGN3,SERPINE2,SSH1,SEMA5B,PIK3R1,FTO,PLXNB1,PLXNB3,PMP22,PRRX1,PACSIN1,TNPO2,FAT3,POU3F2,PPARA,MED1,PPP3CA,PRKCZ,MAPK9,PROX1,RELN,KLK6,GDPD2,PTCH1,PTHLH,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,PPP2R3C,FAT4,RAP1GAP,FEZF2,RET,RFX3,ROBO1,ROBO2,RORB,TMEM100,LRRK2,SOX8,ATAT1,AP1AR,S100B,SALL1,MAPK12,SEMA6D,ATXN1,DRAXIN,FNIP1,SOX6,SGK1,PPP1R9A,CPEB3,FUZ,ST6GAL1,NLGN1,SIRT2,CDK5RAP3,CCDC88A,TRIM67,SLIT1,EPC1,SMARCA4,CDK5RAP2,SMARCD3,RIMS1,SNAP25,SOX2,SOX3,TNIK,SOX5,ZCCHC24,SOX10,SOX11,KDM3A,ZHX3,SPP1,KDM4C,RAP1GAP2,SPART,LMO3,PBLD,CLASP2,MESP1,SMOC1,MAPK8IP3,PHLDB1,KANK1,PLCB1,SYT1,COBL,SYT4,SEMA4A,TAL1,UNC5D,CNTN2,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,CLASP1,SYNE1,OBSL1,CRTC1,TF,DICER1,SIRT1,ZFPM2,TGFBR3,THRA,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,HEY2,TNR,RBFOX2,IL34,NR2C2,TRPS1,ZMYND8,FNDC5,TTC3,TTPA,EIF4ENIF1,GORASP1,FLRT2,VLDLR,P2RY12,WNT7A,XRCC4,NDRG4,CRB2,ZBTB16,PLPPR5,LRP8,RGMA,GDPD5,ADAMTS9,TMEM178A,SEMA3B,ITM2C,FZD3,RTN4,NLRP3,SLC39A12,IFT88" GO: Biological Process GO:0097485 neuron projection guidance 4.76E-15 4.67E-11 6.66E-13 6.51E-12 96 241 "UNC5A,SEMA6A,ALCAM,ANK3,SEMA7A,APBB1,APBB2,APP,SEMA4G,SPTBN4,NRP2,BMP7,BMPR1B,CDK5R1,ISPD,LGI1,NOG,CHN1,SLIT2,LHX2,NRXN3,NRXN1,CRMP1,CSF1R,FEZ2,FEZ1,PLXNA4,BOC,KIF26A,DCC,DPYSL2,DSCAM,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EPHA5,EPHB1,ERBB2,ETV1,TUBB3,FOXG1,SEMA6C,EVL,SEMA4D,DPYSL4,TBR1,FYN,CHL1,GAP43,GBX2,GLI2,RNF165,KIF5A,KIF5C,L1CAM,LAMA2,MATN2,NCAM1,NRCAM,OPHN1,PAX6,SEMA5B,PLXNB1,PLXNB3,MAPK3,RELN,PTK2,PTPRO,FEZF2,ROBO1,ROBO2,SEMA6D,DRAXIN,ARX,SLIT1,USP33,MYCBP2,UNC5B,SPTAN1,SPTB,NFASC,MAPK8IP3,SEMA4A,ROBO3,UNC5D,CNTN2,TNR,FLRT2,ZIC2,DPYSL5,SEMA3B,FZD3,VANGL2" GO: Biological Process GO:0099504 synaptic vesicle cycle 6.12E-15 6.00E-11 8.45E-13 8.26E-12 60 121 "SYT13,DOC2A,AMPH,CADPS,ATP2A2,SYNJ1,CACNA1A,CANX,SYT6,CDH2,CLCN3,NRXN1,RIMS4,RIMS2,SNPH,RIMS3,MAGI2,BLOC1S6,DNM1,SYT15,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIK5,C2CD4C,SYTL4,SYT9,OPHN1,P2RX7,NLGN3,PACSIN1,SYTL2,RAB3A,LRRK2,SYNDIG1,STX1B,ITSN1,SH3GL2,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYT1,SYT4,SYT5,WNT7A,TRIM9,SLC17A7" GO: Biological Process GO:0045666 positive regulation of neuron differentiation 6.22E-15 6.10E-11 8.48E-13 8.28E-12 132 376 "ACHE,KIDINS220,BEND6,LRRC7,SEMA7A,APBB1,SHTN1,CPNE5,ARHGDIA,ASCL1,CAPRIN2,BRINP2,NCOA1,NUMB,BMP7,MMD2,KALRN,HAP1,CAMK2B,SPAG9,CBFA2T2,NEURL1,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,RGS6,FEZ1,RIMS2,IST1,BRINP1,DBN1,DCC,ZEB2,MAGI2,DMD,CDON,SHANK1,DSCAM,HEYL,EIF4G1,EIF4G2,ELAVL4,SEZ6,CDKL3,PTK2B,FGFR1,BAIAP2,FOXG1,SEMA4D,SYT3,NPTN,STAU2,FYN,SYT17,DISC1,ATP8A2,GLI2,STMN2,RAPGEF1,NR3C1,PTPN5,IL1RAPL1,HNRNPK,NEGR1,BRINP3,ITPKA,L1CAM,MAPT,MEF2C,CPNE9,NAP1L2,NBL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,OPA1,PAK3,PALM,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,PROX1,RELN,PTN,PTPRD,PTPRZ1,FEZF2,RET,ROBO1,ROBO2,SALL1,SGK1,PPP1R9A,CPEB3,NLGN1,TRIM67,RIMS1,SOX2,SOX11,KDM4C,MAPK8IP3,SYT1,COBL,SYT4,ACSL6,VWC2,TCF4,CUX2,ZEB1,TCF12,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,ZMYND8,VLDLR,NDRG4,PLPPR5,LRP8,RGMA,GDPD5" GO: Biological Process GO:0060079 excitatory postsynaptic potential 9.93E-15 9.74E-11 1.33E-12 1.30E-11 41 67 "ADORA1,ADORA2A,ADRB2,NLGN4X,MTMR2,DGKI,NRXN1,RIMS2,DBN1,DLG4,DMPK,SHANK1,SEZ6,PTK2B,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,PRKCZ,RELN,LRRK2,STX1B,ATXN1,PPP1R9A,NLGN1,RAB3GAP1,RIMS1,SNCA,STX1A,CUX2,ZMYND8,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0007411 axon guidance 1.05E-14 1.03E-10 1.39E-12 1.36E-11 95 240 "UNC5A,SEMA6A,ALCAM,ANK3,SEMA7A,APBB1,APBB2,APP,SEMA4G,SPTBN4,NRP2,BMP7,BMPR1B,CDK5R1,ISPD,LGI1,NOG,CHN1,SLIT2,LHX2,NRXN3,NRXN1,CRMP1,CSF1R,FEZ2,FEZ1,PLXNA4,BOC,KIF26A,DCC,DPYSL2,DSCAM,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,PLXNC1,EPHA5,EPHB1,ERBB2,ETV1,TUBB3,FOXG1,SEMA6C,EVL,SEMA4D,TBR1,FYN,CHL1,GAP43,GBX2,GLI2,RNF165,KIF5A,KIF5C,L1CAM,LAMA2,MATN2,NCAM1,NRCAM,OPHN1,PAX6,SEMA5B,PLXNB1,PLXNB3,MAPK3,RELN,PTK2,PTPRO,FEZF2,ROBO1,ROBO2,SEMA6D,DRAXIN,ARX,SLIT1,USP33,MYCBP2,UNC5B,SPTAN1,SPTB,NFASC,MAPK8IP3,SEMA4A,ROBO3,UNC5D,CNTN2,TNR,FLRT2,ZIC2,DPYSL5,SEMA3B,FZD3,VANGL2" GO: Biological Process GO:0010769 regulation of cell morphogenesis involved in differentiation 2.36E-14 2.32E-10 3.09E-12 3.02E-11 130 374 "ACHE,AXIN2,SEMA6A,SEMA7A,EPB41L5,LRRC4C,SHTN1,SEMA4G,ARHGDIA,CAPRIN2,DACT3,NUMB,ADGRB3,CDK5R1,ARHGEF7,LDLRAD4,CACNA1A,KALRN,CAMK2B,ARHGEF1,CDC42,CDH2,NUMBL,CHN1,CHRNB2,SLIT2,NGEF,AKAP5,AATK,SIPA1L1,PLXNA4,MYADM,IST1,DBN1,DCC,ZEB2,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,DMTN,CDKL3,OLFM1,FGF13,BAIAP2,MAD2L2,SEMA6C,SEMA4D,PDLIM5,STAU2,TBR1,DISC1,GCNT2,GRIN1,CIT,IL1RAPL1,LINGO1,HAS2,KNDC1,ITPKA,L1CAM,LIMS1,MAG,MAP2,MAPT,MBP,MT3,NRCAM,NTRK2,NTRK3,OMG,PAK3,ENPP2,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,POU3F2,PPP3CA,MAPK9,RELN,PTK2,PTPRD,PTPRO,PTPRZ1,FEZF2,RET,ROBO1,ROBO2,LRRK2,AP1AR,SALL1,SEMA6D,DRAXIN,SGK1,PPP1R9A,FUZ,ST6GAL1,NLGN1,SLIT1,TNIK,SPP1,SPART,PBLD,CLASP2,PHLDB1,KANK1,SEMA4A,CNTN2,CUX2,TCF7L2,CLASP1,SYNE1,OBSL1,TGFBR3,TIAM1,BHLHB9,NR2E1,TNR,TTC3,GORASP1,WNT7A,CRB2,LRP8,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 3.00E-14 2.94E-10 3.87E-12 3.78E-11 71 160 "DSCAML1,PCDH19,PCDH10,PCDHGB4,CADM3,CDH2,CDH8,CDH10,CDH18,NECTIN3,DSCAM,CELSR3,CDHR1,NPTN,CHL1,PCDH17,KIRREL3,PCDH11X,PTPRT,CDH20,L1CAM,CD200,PCDHGC3,PCDH8,PCDH9,PKD1,PCDH18,SDK2,FAT3,DCHS2,PTPRG,FAT4,RET,ROBO1,ROBO2,CLSTN1,IGSF9B,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TRO,CADM1,PCDH20,CADM2,PCDH15" GO: Biological Process GO:0043547 positive regulation of GTPase activity 4.09E-14 4.01E-10 5.21E-12 5.09E-11 193 632 "RALGAPA1,ABR,ACTN2,PLEKHG5,AXIN2,TBC1D14,BCAR3,ARHGAP20,AMPH,BIN1,FGD2,PKP4,ALS2,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,DOCK11,ADGRB3,RGS11,RGS9,FGF17,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,RGN,ARHGEF1,ARHGEF2,ARHGAP33,EVI5L,RCBTB2,CHM,CHN1,CHN2,CHRM4,ARHGAP22,NGEF,ARHGEF6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,GIT2,ELMO1,TIAM2,SRGAP3,SGSM2,RABGAP1L,DLG4,DOCK2,RASGRP1,FAM13A,EGFR,RASA4,EIF5,RGS17,RASGRP2,ERBB2,ERBB4,DENND4A,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,PSD2,ARFGAP2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,GNAO1,GNAS,ADAP1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,ARHGAP19,NCKAP1L,ARHGAP36,AGFG1,SMAP1,DOCK7,KNDC1,INPP5B,JAK1,JAK2,KIT,STXBP5,LIMS1,ARHGAP12,SHC3,KITLG,AFDN,GIT1,MYO9A,NCAM1,NF1,NTRK3,TBC1D25,OCRL,OPHN1,PDGFRA,PLXNB1,RASGEF1B,PSD,BCAS3,PTK2,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,SGSM1,LRRK2,SBF1,FNIP1,ELMOD1,RASA3,ITSN1,ASAP3,DOCK10,PREX2,RAB3GAP1,ARHGEF40,ARFGAP1,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,ST5,RGL1,FGD4,ARHGEF9,PLCB1,MCF2L,DNMBP,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,TIAM1,TRIO,TSC1,TSC2,VAV1,VAV2,TBC1D15,P2RY12,EVI5,DOCK8,SPATA13" GO: Biological Process GO:0050768 negative regulation of neurogenesis 4.17E-14 4.09E-10 5.24E-12 5.12E-11 106 285 "ADCY6,DISP3,SEMA6A,SEMA7A,APBB1,APP,SEMA4G,ARHGDIA,ASCL1,BMP7,CDK5R1,RAB29,ARHGEF1,CBFA2T2,ARHGEF2,NOG,GPR37L1,ADGRG1,SLIT2,NGEF,MAP4K4,CRMP1,AATK,BRINP1,DCC,KIAA0319,NTM,DLX1,EDNRB,SEMA3D,OLIG2,SEZ6,ERBB4,CDKL3,EFEMP1,OLFM1,FGF13,FGFR3,FOXG1,SEMA6C,FOXO3,SEMA4D,DLL3,NRG3,NKX6-2,GFAP,STMN2,CIT,SOX21,LINGO1,RBPJ,HES5,MAG,MBD1,MBP,MEIS1,MT3,MYCN,NF1,NKX2-2,NTRK3,OMG,PAX6,PBX1,GPR173,NLGN3,SEMA5B,PMP22,FAT3,MED1,PPP3CA,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,SOX8,SEMA6D,DRAXIN,NLGN1,SIRT2,SLIT1,CDK5RAP2,SOX2,SOX3,SOX11,SPP1,RAP1GAP2,SPART,KANK1,SEMA4A,CNTN2,DICER1,HEY1,NR2E1,TNR,TTC3,EIF4ENIF1,GORASP1,WNT7A,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0023061 signal release 6.26E-14 6.14E-10 7.69E-12 7.51E-11 160 498 "ABAT,SYN3,ASIC1,ADCY5,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,MADD,CASK,ARNTL,ARRB1,CADPS,PDE8B,ATP2A2,SYNJ1,ARHGEF7,BTK,BAIAP3,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CAMK2A,CAMK2G,SYT6,BRSK2,CCKBR,CD38,DGKI,CACNA2D2,NRXN3,NRXN1,NRXN2,MAP4K4,CNR1,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SLC32A1,SNCAIP,RIMS4,RIMS2,SNPH,RIMS3,C2CD2L,BLOC1S6,SNAP91,EDN1,EDN3,SYT15,SIDT2,EGFR,EPHA5,STX2,FGFR1,SYT3,BRSK1,OGA,GABBR1,ILDR2,GAD1,GAD2,GALR1,SYT17,CPLX2,CPLX1,GCK,GDF9,GLUL,KCNMB4,GNAS,GPER1,PCLO,RAPGEF4,GRIK5,GRM8,HRH3,HMGCR,HTR2A,ICA1,C2CD4C,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MEF2C,MYO5A,MYT1,NELL2,NEUROD1,NF1,NNAT,NOS1,NTRK2,NUCB2,P2RX7,P2RY1,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,SYTL2,PTPRN,PTPRN2,RAB3A,RFX3,LRRK2,WLS,STX1B,SMPD3,SCG5,PPP1R9A,SYBU,NLGN1,RPH3A,SLC6A9,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,SOX11,STX1A,STXBP1,SYT11,ABCC8,SYN1,SYN2,SYT1,SYT4,SYT5,TAC1,TACR1,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1,WNT7A,TRIM9" GO: Biological Process GO:0050807 regulation of synapse organization 6.27E-14 6.15E-10 7.69E-12 7.51E-11 60 126 "ASIC2,SLITRK1,ADGRB1,ADGRB2,ADGRB3,CAMK2B,CBLN1,NEURL1,CDC42,CDH2,CHRNB2,NRXN3,NRXN1,NCAN,SLITRK5,FRMPD4,DBN1,MAGI2,DMPK,EPHB1,PDLIM5,STAU2,DISC1,PCDH17,GRIN1,HNRNPK,LRRTM3,LRRTM1,LRRC4B,MEF2C,MDGA1,NEUROD2,NTRK2,NTRK3,OXTR,NLGN3,LRRN3,RELN,PTK2,PTN,ROBO2,SYNDIG1,LRRTM4,PPP1R9A,SLITRK3,NLGN1,CLSTN1,SLIT1,CLSTN2,LRRC4,ADGRL3,CUX2,BHLHB9,LRRC24,ZMYND8,LRTM2,FLRT2,FLRT1,WNT7A,CBLN2" GO: Biological Process GO:0097479 synaptic vesicle localization 1.53E-13 1.50E-09 1.85E-11 1.81E-10 64 141 "SYT13,DOC2A,AMPH,CNIH2,CADPS,ATP2A2,SYNJ1,CACNA1A,CANX,SYT6,CDH2,NRXN1,RIMS4,RIMS2,SNPH,RIMS3,MAGI2,BLOC1S6,DNM1,DNM2,DPYSL2,SYT15,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,SYT9,BLOC1S2,OPHN1,P2RX7,NLGN3,PACSIN1,SYTL2,RAB3A,LRRK2,SYNDIG1,STX1B,ITSN1,SH3GL2,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYT1,SYT4,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0034220 ion transmembrane transport 1.69E-13 1.65E-09 2.02E-11 1.97E-10 290 1064 "TTYH1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,SLC12A5,SLC24A4,AGT,PLA2G6,UNC79,KCNT1,DPP10,ANK2,ANK3,CNIH2,KCNAB2,SHROOM2,AQP4,AQP6,SLC7A14,CASK,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,RIPK1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,SLC16A4,P2RX6,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,NRXN1,SLC24A2,STOML1,CNGA3,AKAP7,AKAP6,SLC4A7,SLC4A8,COX4I1,CRHBP,SLC32A1,NOS1AP,CYBB,TCAF1,DAPK1,DBI,CNIH3,DLG3,DLG4,GRIN3A,DMD,DNM2,SHANK1,SLC12A6,DPP6,DRD1,ABCC5,ABCC9,EDN3,EDNRA,SGK2,CACNG7,KCNMB2,SLC43A2,NCALD,CACNG3,CACNG2,PTK2B,ATP8A1,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,PCYOX1,ATP13A4,SLC37A3,TMEM175,HVCN1,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CAB39,AHCYL1,JPH4,PPARGC1A,GLRB,KCNMB4,GPM6A,GPER1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,GRM7,IL1RAPL1,HTR2A,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,SFXN5,MEF2C,MYO5A,FXYD7,FXYD6,NOS1,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PIRT,PDPK1,BEST3,NLGN3,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,SLC36A4,PRKAB2,SLC26A11,RELN,PTAFR,RASGRF1,RASGRF2,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SGK1,NLGN1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A7,SLC6A8,SLC6A9,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,UNC80,SCN3B,MLC1,ABCC8,ARHGEF9,PLCB1,ARC,SLC37A2,ANO4,ACSL6,TPCN2,ATP13A2,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,SGK3,UBC,BEST1,P2RY12,SLC13A3,KCNK12,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,WNK1,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,TMEM63C,SLC39A12,NETO2,SLC4A10,JPH3" GO: Biological Process GO:0050773 regulation of dendrite development 3.90E-13 3.82E-09 4.61E-11 4.50E-10 66 150 "ACHE,CAPRIN2,NUMB,ADGRB3,BMP7,CDK5R1,KALRN,CAMK2B,NEURL1,NUMBL,CHRNB2,NGEF,AKAP5,SIPA1L1,DBN1,DCC,KIAA0319,SHANK1,EIF4G2,ELAVL4,SEZ6,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,DISC1,RAPGEF4,GRIN1,NR3C1,CIT,IL1RAPL1,HNRNPK,KNDC1,ITPKA,MEF2C,NTRK2,OPA1,PAK3,PALM,NLGN3,PACSIN1,FAT3,PPP3CA,RELN,PTPRD,PTPRZ1,ROBO1,LRRK2,SGK1,PPP1R9A,CPEB3,NLGN1,TNIK,COBL,CUX2,SYNE1,OBSL1,CRTC1,TIAM1,BHLHB9,NR2E1,ZMYND8,GORASP1,VLDLR,LRP8" GO: Biological Process GO:0030029 actin filament-based process 4.46E-13 4.37E-09 5.21E-11 5.09E-10 202 685 "ABR,ACTN1,ACTN2,FMNL2,ADD1,ADD2,ERMN,MRTFA,CDC42BPA,ANK2,FGD2,PPFIA1,APBB1,APBB2,EPB41L5,GAS7,SHTN1,SHROOM2,SPTBN4,ARHGDIA,ARRB1,DYNLL1,ATP1A1,ATP1A2,ATP2A2,CFLAR,CDK5R1,WASF1,CACNA2D1,CACNB2,LURAP1,CAMK2D,CAPN3,BRSK2,FMNL3,ARHGEF2,CDC42,CFL2,TAOK2,SLIT2,MYL6B,CNN3,PICK1,AKAP6,BAG4,MYRIP,CDC42BPB,CSF1R,ARHGEF10,MICAL2,SIPA1L1,NOS1AP,MYADM,DAPK3,SIRPA,DBN1,ELMO1,DMD,SHANK1,DOCK2,ABI1,DNAJB6,USH1C,EDN1,FRY,ABI2,SORBS3,TENM1,EPB41,EPB41L1,EPB41L2,DMTN,EPHA5,EPS8,PTK2B,CORO2B,DLC1,TESK2,FER,FGF12,BAIAP2,MAD2L2,FGR,AGAP2,EVL,FLNC,SORBS1,ATP2C1,STAU2,ABLIM2,NCKAP1,IQGAP2,INPP5K,WASF3,ARFIP1,RND1,GPM6B,CIT,GSN,PACSIN2,NCKAP1L,SYNPO,SMAP1,MYLK2,SCIN,ITPKA,JAK2,KCNH2,KIT,MEF2C,MKLN1,DBNL,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,NF1,NTRK3,OPHN1,PAK3,PDE4B,PDE4D,PDGFRA,PDPK1,TMOD2,SSH1,PIK3R1,FXYD1,MAGEL2,EPB41L4B,PACSIN1,PRKCZ,PROX1,BCAS3,GDPD2,IQSEC3,RAP1GDS1,RDX,MYH14,KIRREL1,AP1AR,SCN2B,SCN4B,MRAS,PPP1R9A,PPM1E,ASAP3,MYO18A,FHOD3,ABLIM3,CCDC88A,TTC17,LIMCH1,PALLD,SCN3B,TNIK,ARHGAP26,SPTAN1,SPTB,IQSEC2,CLASP2,EPB41L3,KANK1,FGD4,SYNE2,COBL,TAC1,TACR1,MLST8,CLASP1,OBSL1,FRYL,TEK,TF,TMOD1,DAAM2,PARD3,TNNT1,TPM1,TPM2,TPM3,TPM4,KCNE5,TSC1,TMEFF2,AMOT,PLEKHH2,MICAL1,WIPF1,RICTOR,FMN2,SPIRE1,PCDH15,WIPF2,ACTR3B,VANGL2,FRMD6" GO: Biological Process GO:0010001 glial cell differentiation 5.52E-13 5.41E-09 6.37E-11 6.22E-10 83 210 "ADORA2A,AGT,BIN1,PRX,ASCL1,ASPA,MYRF,CDH2,NOG,GPR37L1,CLU,QKI,PICK1,TENM4,ARHGEF10,DLX1,DMD,OLIG1,MED12,DRD1,EGFR,OLIG2,ERBB2,ERCC2,PRMT5,FGFR3,DLL3,NKX6-2,GAP43,WASF3,DNER,GFAP,GSN,LINGO1,IGF1,HES5,IL6ST,ITGAM,KCNJ10,LAMA2,MAG,MBD1,AFDN,ADAM22,MT3,MYCN,NF1,NFIX,NKX2-2,NTRK2,NTRK3,OMG,PAX6,ENPP2,NLGN3,SERPINE2,PLP1,FA2H,POU3F2,MAPK3,RELN,PTPRZ1,SH3TC2,SOX8,S100B,SOX6,SLC8A3,SIRT2,SMARCA4,SOX2,SOX5,SOX10,SOX11,TAL1,CNTN2,TCF7L2,DICER1,TLR4,NR2E1,PARD3,LGI4,PRDM8,RTN4" GO: Biological Process GO:0050805 negative regulation of synaptic transmission 6.36E-13 6.24E-09 7.25E-11 7.08E-10 42 76 "ASIC1,ACHE,ABHD6,ADORA1,NLGN4X,PLA2G6,CNIH2,BCHE,MTMR2,CD38,DGKI,SLC24A2,PICK1,PNKD,DRD1,PTK2B,STAU2,GABBR1,PCDH17,GPM6B,RAPGEF4,GRIA1,GRIK1,GRIK2,GRIK3,HTR2A,KCNB1,MAPT,NF1,NOS1,NLGN3,LRRK2,PPP1R9A,SLC6A1,SHANK2,SORCS3,SNCA,IQSEC2,STXBP1,SYT11,TNR,CELF4" GO: Biological Process GO:0010721 negative regulation of cell development 7.08E-13 6.95E-09 7.99E-11 7.80E-10 121 354 "ADCY6,DISP3,SEMA6A,SEMA7A,PI16,APBB1,APP,SEMA4G,ARHGDIA,ASCL1,DACT3,BMP7,CDK5R1,RAB29,LDLRAD4,ARHGEF1,CBFA2T2,ARHGEF2,NOG,GPR37L1,ADGRG1,SLIT2,NGEF,TJP2,MAP4K4,CRMP1,AATK,BRINP1,DCC,KIAA0319,NTM,DLX1,EDNRB,SEMA3D,OLIG2,DMTN,SEZ6,ERBB4,CDKL3,EFEMP1,OLFM1,FGF13,FGFR3,MAD2L2,FOXG1,SEMA6C,FOXO3,SEMA4D,DLL3,NRG3,NKX6-2,GFAP,STMN2,CIT,SOX21,LINGO1,IGF1,RBPJ,HES5,MAG,MBD1,MBP,MEIS1,MT3,MYCN,NF1,NKX2-2,NODAL,NPR2,NTRK3,OMG,PAX6,PBX1,GPR173,NLGN3,SEMA5B,PMP22,FAT3,MED1,PPP3CA,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,SOX8,AP1AR,SALL1,SEMA6D,DRAXIN,FUZ,NLGN1,SIRT2,SLIT1,CDK5RAP2,SOX2,SOX3,SOX11,SPP1,RAP1GAP2,SPART,PBLD,KANK1,SEMA4A,CNTN2,DICER1,TGFBR3,HEY1,NR2E1,TNR,TTC3,TTPA,EIF4ENIF1,GORASP1,WNT7A,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0015672 monovalent inorganic cation transport 1.73E-12 1.70E-08 1.93E-10 1.88E-09 184 617 "ABAT,KCNH8,ASIC2,ASIC1,ACTN2,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRB2,SLC24A4,SLC44A5,AGT,KCNT1,DPP10,ANK1,ANK2,ANK3,KCNAB2,SHROOM2,SPTBN4,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP6V1G2,ATP6V0A1,HCN2,BTK,CACNA1A,CACNA1D,CAMK2D,SLC25A14,CCKBR,SLC5A11,KCNAB3,ASIC3,CHRNA4,CHRNB2,SLC24A2,STOML1,CNGA3,CNR1,CNTN1,AKAP7,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,COX4I1,NOS1AP,KLHL3,DMD,DMPK,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN1,EDN3,EDNRA,SGK2,KCNMB2,PTK2B,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,TMEM175,HVCN1,ATP6V1H,GABBR1,CAB39,AHCYL1,GCK,KCNMB4,GNAS,GPM6B,SLC2A6,HRH3,HTR2A,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NAT8L,MAOB,NOS1,NPPA,SLC11A2,HCN1,P2RX7,KCNK10,SLC10A4,ABCB1,SERPINE2,NALCN,TMEM38A,FXYD1,NKAIN4,PRKAB2,PRKCB,NKAIN1,SLC6A15,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,SMPD3,ASIC4,SEC14L1,SGK1,SLC6A8,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLC22A4,SNAP25,SNCA,SCN3B,NKAIN2,ABCC8,PLCB1,AZIN2,SLC44A1,TRPM2,KCNE5,TSC1,SGK3,SLC35A4,P2RY12,SLC13A3,KCNK12,KCNT2,ATP6V0E2,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,RTN4,SLC4A10" GO: Biological Process GO:0014047 glutamate secretion 2.00E-12 1.96E-08 2.20E-10 2.15E-09 33 53 "ADORA1,ADORA2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CCK,DPYSL2,GABBR1,CPLX1,GLS,NR3C1,GRM2,GRM7,HRH3,MYO6,NF1,NTRK2,P2RX7,RAB3A,SLC1A2,SLC1A3,SLC1A6,SLC1A7,RAB3GAP1,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,TRH,SLC17A7" GO: Biological Process GO:0006813 potassium ion transport 2.25E-12 2.20E-08 2.45E-10 2.39E-09 85 222 "KCNH8,ACTN2,SLC12A5,ADORA1,ADRB2,SLC24A4,KCNT1,DPP10,ANK2,ANK3,KCNAB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,HCN2,CACNA1D,KCNAB3,SLC24A2,CNGA3,AKAP7,AKAP6,AKAP5,NOS1AP,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN3,KCNMB2,PTK2B,FHL1,TMEM175,CAB39,GCK,KCNMB4,HTR2A,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NOS1,NPPA,HCN1,KCNK10,TMEM38A,KCNIP3,KCNIP2,KCNIP1,SLC12A2,SLC12A4,SNAP25,ABCC8,KCNE5,TSC1,P2RY12,KCNK12,KCNT2,KCNAB1" GO: Biological Process GO:0044057 regulation of system process 2.74E-12 2.69E-08 2.96E-10 2.89E-09 176 586 "ABAT,ASIC2,ADCY6,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,C1QTNF1,C1QTNF3,ANK2,PI16,MADD,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,MTMR2,CACNA1G,MYRF,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,CAMK2D,CAMK2G,CCK,CCKBR,CD38,CACNA2D2,CHGA,CHRM1,AKAP6,CPS1,CRHBP,CRY2,TENM4,NOS1AP,DOCK4,HDAC4,DAPK3,DBN1,DMD,DMPK,DRD1,ABCC9,EDN1,EDN3,EDNRB,CACNG7,EGFR,CALCRL,KCNMB2,MRVI1,CACNG3,CACNG2,FCGR3A,FGFR1,FLT1,OGA,GAA,AHCYL1,GALR1,INPP5K,WASF3,MSTN,GDF9,PPARGC1A,GLS,KCNMB4,GNAO1,GNAS,GPER1,RAPGEF4,GRIN2D,NR3C1,GRM1,GRM3,BVES,GUCY1A1,HMGCR,HSP90AA1,HTR2A,MYLK2,IGF1,IL6ST,JAK2,KCNA1,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK3,KCNMA1,FGFBP3,MAG,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NCAM1,NEUROD1,NOS1,NPPA,NPR2,NUCB2,OPRL1,OXTR,P2RY1,PDE4B,PDE4D,NLGN3,PIK3R1,FTO,FXYD1,PPP3CA,PTAFR,PTK2,PTPRO,TMEM100,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SGK1,NLGN1,SLC8A2,SLC8A1,SLC8A3,SLN,SCN3B,SP4,SSTR2,TAC1,TACR1,TF,DICER1,SIRT1,SPX,THRA,TLR4,HEY2,PARD3,TNNT1,TNR,TPM1,TRPC1,TRPC3,KCNE5,WNK1,WNK3,RTN4" GO: Biological Process GO:0030001 metal ion transport 2.92E-12 2.86E-08 3.11E-10 3.04E-09 238 855 "TTYH1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRB2,SLC24A4,AGT,PLA2G6,KCNT1,DPP10,ANK2,ANK3,KCNAB2,CACHD1,SHROOM2,CASK,SPTBN4,ARRB2,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,SLC5A11,RGN,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRNA4,CHRNB2,SLC24A2,STOML1,CLTC,CNGA3,CNTN1,AKAP7,AKAP6,AKAP5,SLC4A7,SLC4A8,CP,NOS1AP,DBI,HEPH,KLHL3,GRIN3A,DMD,DMPK,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN3,EDNRA,SGK2,CACNG7,CALCRL,KCNMB2,CACNG3,CACNG2,PTK2B,SLC9B2,FGF12,FGF14,FHL1,TMEM175,ATP6V1H,ATP2C1,SARAF,OGA,FYN,CAB39,AHCYL1,JPH4,INPP5K,GCK,KCNMB4,GNAO1,GNAS,GPM6A,MCHR1,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,IGF1,ITGAV,SLC35G1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MT3,MYO5A,NOS1,NPY,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PDPK1,SLC10A4,SERPINE2,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,PPP3CA,NKAIN4,PRKCB,CNNM2,NKAIN1,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SGK1,SLC6A8,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,SCN3B,NKAIN2,ABCC8,PLCB1,TPCN2,TF,TRPC1,TRPC3,TRPM2,KCNE5,TSC1,SGK3,BEST1,P2RY12,SLC13A3,KCNK12,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0030534 adult behavior 3.70E-12 3.63E-08 3.90E-10 3.81E-09 70 170 "ABAT,SLITRK1,ADRA1B,NLGN4X,UNC79,APP,SPTBN4,ARRB2,ATP1A2,ATP1A3,BBS2,CACNA1A,CACNB4,KALRN,CHRNA4,CHRNB2,NRXN3,CLCN3,NRXN1,NRXN2,CRHBP,CNTNAP2,SLITRK5,PUM1,DNM1,SHANK1,DRD1,SEZ6L2,EFNB3,SEZ6,EPS8,CEND1,FGF12,FGF14,CHL1,GABRG2,PCDH17,GLRB,GRIK1,GRIN1,GRIN2D,GRM7,HTR2A,KCNJ10,KCNMA1,FGFBP3,MAPT,ADAM22,NOS1,NPY,SLC10A4,NLGN3,PPARA,OXR1,ATXN1,SCN8A,SLC1A2,PREX2,SHANK2,SNCA,CNTN2,AGTPBP1,TMOD1,SEZ6L,TRH,TSC1,UCHL1,LGI4,ZIC1,PCDH15" GO: Biological Process GO:0071805 potassium ion transmembrane transport 4.30E-12 4.21E-08 4.44E-10 4.33E-09 73 181 "KCNH8,ACTN2,SLC12A5,KCNT1,DPP10,ANK2,ANK3,KCNAB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,HCN2,CACNA1D,KCNAB3,CNGA3,AKAP7,AKAP6,NOS1AP,DNM2,SLC12A6,DPP6,ABCC9,EDN3,KCNMB2,FHL1,TMEM175,CAB39,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NPPA,HCN1,KCNK10,TMEM38A,KCNIP3,KCNIP2,KCNIP1,SLC12A4,SNAP25,ABCC8,KCNE5,P2RY12,KCNK12,KCNT2,KCNAB1" GO: Biological Process GO:0071804 cellular potassium ion transport 4.30E-12 4.21E-08 4.44E-10 4.33E-09 73 181 "KCNH8,ACTN2,SLC12A5,KCNT1,DPP10,ANK2,ANK3,KCNAB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,HCN2,CACNA1D,KCNAB3,CNGA3,AKAP7,AKAP6,NOS1AP,DNM2,SLC12A6,DPP6,ABCC9,EDN3,KCNMB2,FHL1,TMEM175,CAB39,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NPPA,HCN1,KCNK10,TMEM38A,KCNIP3,KCNIP2,KCNIP1,SLC12A4,SNAP25,ABCC8,KCNE5,P2RY12,KCNK12,KCNT2,KCNAB1" GO: Biological Process GO:0050905 neuromuscular process 4.77E-12 4.68E-08 4.87E-10 4.76E-09 55 120 "ABR,ADCY5,ADORA2A,CNTNAP1,KCNAB2,APP,PDE8B,ATP2B2,CACNA1A,CAMK2B,NRXN1,TPP1,IGDCC3,PNKD,DBN1,DLG4,GRIN3A,SHANK1,DRD1,USH1C,FABP7,FGF12,FGF14,GAA,JPH4,NKX6-2,ATP8A2,GLRB,GRIN1,GRIN2C,GRIN2D,KCNA1,KCNH1,KCNMA1,MYO5A,MYO7A,GPR88,PENK,PEX5,PRRT2,ATXN2,SCN8A,SLC1A3,ANKFN1,SOX2,NPAS3,SPART,CAMTA1,AGTPBP1,CSMD1,TNR,RBFOX2,UCHL1,PCDH15,JPH3" GO: Biological Process GO:0099565 "chemical synaptic transmission, postsynaptic" 6.99E-12 6.86E-08 7.07E-10 6.91E-09 51 108 "ABAT,ADORA1,ADORA2A,ADRB2,NLGN4X,ARRB2,MTMR2,DGKI,CHRNA4,CHRNB2,NRXN1,RIMS2,DBN1,DLG4,DMPK,SHANK1,SEZ6,PTK2B,GABRA2,GABRA3,GABRA4,GABRB3,GABRG2,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,PRKCZ,RELN,LRRK2,STX1B,ATXN1,PPP1R9A,NLGN1,RAB3GAP1,IGSF9B,RIMS1,SNCA,STX1A,CUX2,ZMYND8,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0045597 positive regulation of cell differentiation 8.34E-12 8.18E-08 8.34E-10 8.15E-09 261 966 "ACHE,AXIN2,KIDINS220,BEND6,AGT,LRRC7,SEMA6A,BIN1,OGT,SEMA7A,APBB1,APC,EPB41L5,SHTN1,CPNE5,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,PTCH2,BRINP2,NCOA1,NUMB,RIPK1,PROM1,BMP7,BMPR1B,SYNJ1,ARHGEF7,BTK,MMD2,KALRN,HAP1,CAMK2B,SPAG9,CD86,CBFA2T2,NEURL1,CDC42,CDH2,NOG,NUMBL,SLIT2,CPNE6,CLU,QKI,CNR1,CNTN1,AKAP6,AKAP5,ZNF385A,CSF1,TENM4,CSF1R,RGS6,FEZ1,SOCS5,CTH,RIMS2,CX3CR1,BOC,MYADM,MAML1,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,BLOC1S6,CCDC3,DMD,CDON,DNM2,SHANK1,DSCAM,EDN1,EDN3,HEYL,RASGRP1,EGR3,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,SEZ6,CDKL3,PTK2B,PRMT5,SLC9B2,OLFM1,FGFR1,FGFR3,BAIAP2,SUCO,FOXG1,FOXO3,SEMA4D,FLT1,SYT3,TRIM16,NPTN,DLL3,STAU2,FYN,NKX6-2,SYT17,DISC1,ATP8A2,GCNT2,GFAP,GLI2,KDM2B,GNAS,GPER1,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,ATOH8,WIF1,HAS2,NCKAP1L,HMGB1,HNRNPK,NEGR1,HSP90AA1,SMAP1,HTR2A,IFI16,IGF1,RBPJ,SCIN,IL6R,IL6ST,IL12A,BRINP3,INSM1,ITPKA,ITPKB,JAK2,KIT,L1CAM,LIG4,LIMS1,SMAD1,SMAD9,MAG,MAPT,MEF2C,KITLG,CPNE9,MSR1,NAP1L2,NBL1,NELL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NRCAM,NTRK2,NTRK3,DDR2,OPA1,PAK3,PALM,PAX6,PDE3A,ENPP2,NLGN3,SERPINE2,PIK3R1,PLXNB1,PLXNB3,PACSIN1,MED1,PRKCZ,MAPK9,PROX1,RELN,GDPD2,PTCH1,PTK2,PTN,PTPRD,PTPRZ1,PPP2R3C,FEZF2,RET,RFX3,ROBO1,ROBO2,TMEM100,SOX8,SALL1,MAPK12,ATXN1,SOX6,SGK1,PPP1R9A,CPEB3,NLGN1,SIRT2,TRIM67,EPC1,SMARCA4,SMARCD3,RIMS1,SOX2,SOX5,SOX10,SOX11,ZHX3,KDM4C,LMO3,MESP1,MAPK8IP3,PLCB1,SYT1,COBL,SYT4,TAL1,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,OBSL1,CRTC1,TF,DICER1,SIRT1,THRA,TIAM1,HEY1,BHLHB9,IL34,NR2C2,ZMYND8,FNDC5,VLDLR,XRCC4,NDRG4,CRB2,ZBTB16,PLPPR5,LRP8,RGMA,GDPD5,ADAMTS9,FZD3,RTN4,NLRP3" GO: Biological Process GO:0034765 regulation of ion transmembrane transport 8.64E-12 8.48E-08 8.56E-10 8.36E-09 143 455 "KCNH8,ASIC2,ACTN2,AGT,PLA2G6,DPP10,ANK2,ANK3,CNIH2,KCNAB2,CASK,ASPH,ATP1A2,ATP1B3,RIPK1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,KCNAB3,CACNA2D2,CBARP,CHRNA4,CLCN3,CLCN4,NRXN1,STOML1,AKAP7,AKAP6,CRHBP,NOS1AP,CYBB,TCAF1,DAPK1,DBI,CNIH3,DLG4,DMD,DNM2,SHANK1,DPP6,DRD1,EDN3,EDNRA,CACNG7,CACNG3,CACNG2,PTK2B,FGF12,FGF14,FHL1,HVCN1,CAB39,AHCYL1,JPH4,PPARGC1A,GPER1,GRIK1,GRIN1,GRIN2D,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNMA1,KCNN2,KCNQ2,KCNQ3,MEF2C,MYO5A,NOS1,NPPA,HCN1,OPRL1,P2RX7,KCNK10,PDE4B,PDE4D,PIRT,PDPK1,NLGN3,NALCN,PIK3C2A,FXYD1,RELN,PTAFR,RASGRF1,RASGRF2,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,NLGN1,SLC8A1,SLN,SNCA,SCN3B,PLCB1,ARC,ACSL6,TPCN2,TRPC1,KCNE5,KCNK12,WNK1,KCNAB1,WNK3,WNK2,NETO2,JPH3" GO: Biological Process GO:0045665 negative regulation of neuron differentiation 9.02E-12 8.84E-08 8.84E-10 8.64E-09 85 227 "ADCY6,DISP3,SEMA6A,SEMA7A,APBB1,APP,SEMA4G,ARHGDIA,ASCL1,BMP7,CDK5R1,RAB29,ARHGEF1,CBFA2T2,GPR37L1,SLIT2,NGEF,MAP4K4,CRMP1,AATK,DCC,KIAA0319,NTM,EDNRB,SEMA3D,OLIG2,SEZ6,CDKL3,EFEMP1,FGF13,FOXG1,SEMA6C,FOXO3,SEMA4D,GFAP,STMN2,CIT,SOX21,LINGO1,RBPJ,HES5,MAG,MBP,MEIS1,MT3,NKX2-2,OMG,PAX6,PBX1,NLGN3,SEMA5B,PMP22,FAT3,MED1,PPP3CA,PTK2,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,SOX8,SEMA6D,DRAXIN,NLGN1,SLIT1,CDK5RAP2,SOX2,SOX3,SPP1,RAP1GAP2,SPART,KANK1,SEMA4A,CNTN2,HEY1,NR2E1,TNR,TTC3,EIF4ENIF1,GORASP1,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0097480 establishment of synaptic vesicle localization 1.59E-11 1.56E-07 1.53E-09 1.50E-08 58 133 "SYT13,DOC2A,AMPH,CNIH2,CADPS,ATP2A2,SYNJ1,CACNA1A,CANX,SYT6,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,DNM1,DNM2,DPYSL2,SYT15,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,SYT9,BLOC1S2,OPHN1,P2RX7,PACSIN1,SYTL2,RAB3A,LRRK2,STX1B,ITSN1,SH3GL2,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYT1,SYT4,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0048489 synaptic vesicle transport 1.59E-11 1.56E-07 1.53E-09 1.50E-08 58 133 "SYT13,DOC2A,AMPH,CNIH2,CADPS,ATP2A2,SYNJ1,CACNA1A,CANX,SYT6,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,DNM1,DNM2,DPYSL2,SYT15,STX2,FGF14,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,MYLK2,C2CD4C,SYTL4,SYT9,BLOC1S2,OPHN1,P2RX7,PACSIN1,SYTL2,RAB3A,LRRK2,STX1B,ITSN1,SH3GL2,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT11,SYN1,SYT1,SYT4,SYT5,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0051345 positive regulation of hydrolase activity 2.15E-11 2.11E-07 2.05E-09 2.00E-08 251 929 "RALGAPA1,ABR,ACTN2,PLEKHG5,ADCYAP1R1,AXIN2,ADRB2,AGT,TBC1D14,BCAR3,ARHGAP20,AMPH,BIN1,FGD2,C6orf89,PKP4,APAF1,ALS2,APOC2,APP,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ASPH,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,FGF17,BID,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,CCK,RGN,AIFM1,ARHGEF1,ARHGEF2,ARHGAP33,EVI5L,RCBTB2,CHM,CHN1,CHN2,CHRM4,ARHGAP22,NGEF,ARHGEF6,AKAP6,NRG2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,DAPK1,GIT2,ELMO1,TIAM2,MAGI2,SRGAP3,SGSM2,RABGAP1L,DLG4,DNM2,DOCK2,CASP8AP2,DNAJB6,FIS1,EDNRA,RASGRP1,FAM13A,EGFR,RASA4,EIF5,RGS17,PCOLCE2,RASGRP2,ERBB2,ERBB4,DENND4A,F3,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,ARFGAP2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,GNAO1,GNAS,ADAP1,GPER1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,GSN,ARHGAP19,NCKAP1L,ARHGAP36,HMGB1,GABARAPL2,HPCA,AGFG1,SMAP1,HTR2A,IFI16,DOCK7,KNDC1,INPP5B,JAK1,JAK2,KIT,STXBP5,LIMS1,ARHGAP12,SHC3,MEF2C,KITLG,AFDN,GIT1,MYL3,MYO9A,NCAM1,NF1,NODAL,SLC11A2,NTRK3,TBC1D25,OCRL,OPHN1,PDCD2,PDGFRA,PDPK1,PLCB2,PLXNB1,PTPA,RASGEF1B,PRKCZ,MAPK8,MAPK9,PSD,BCAS3,PTAFR,PTK2,RAB3A,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,ROBO1,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,ELMOD1,RASA3,ITSN1,ASAP3,DOCK10,PREX2,RAB3GAP1,ARHGEF40,ARFGAP1,SNCA,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,ST5,RGL1,FGD4,ARHGEF9,DNAJC9,PLCB1,MTCL1,MCF2L,DNMBP,TCEA1,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,SIRT1,TIAM1,TPM1,TRIO,TSC1,TSC2,BCL2L13,MTCH1,VAV1,VAV2,TBC1D15,LMF1,P2RY12,WRN,EVI5,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:0006928 movement of cell or subcellular component 2.35E-11 2.30E-07 2.21E-09 2.16E-08 455 1882 "ABR,ABHD6,ACTN1,ACTN2,PLEKHG5,ADORA1,UNC5A,ADORA3,AP2A1,AP2A2,MTUS1,AGT,HACE1,NME5,WDR35,OSBPL8,SEMA6A,ALCAM,MRTFA,KIF6,CDC42BPA,ANK2,ANK3,SEMA7A,CNIH2,APBB1,APBB2,APC,EPB41L5,DGKZ,APP,SHTN1,SHROOM2,SEMA4G,SPTBN4,ARHGAP5,ARHGDIA,ARRB2,ASCL1,DNAH17,CHRD,NUMB,ASTN1,DYNLL1,ATP1A1,ATP1A2,ATP1B3,ATP2A2,KIF1A,ADAM15,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,DST,ARHGEF7,CACNA1I,C5,WASF1,CDK5R2,IL33,LDLRAD4,CACNA1E,DDR1,CACNA2D1,CACNB2,LURAP1,HAP1,CAMK2D,ISPD,SPAG9,CCK,LDB2,KRIT1,FMNL3,RGN,SCARB1,NEURL1,CD81,CDC42,CDH2,DCLK1,LGI1,NOG,ADGRG1,CHGA,CHN1,JAM2,TAOK2,SLIT2,LHX2,NRXN3,NRXN1,MYL6B,CLTA,CCDC151,AKAP6,BAG4,MYRIP,NRG2,CDC42BPB,SH2B1,CRMP1,CSF1,CSF1R,CSF3R,FEZ2,FEZ1,VCAN,PLXNA4,SDC3,CX3CR1,NOS1AP,BOC,DOCK4,HDAC9,MYADM,TCAF1,ARHGAP24,HDAC4,KIF26A,DAPK3,SIRPA,DBN1,DCC,DCTN1,ZEB2,ELMO1,KIAA0319,MAGI2,BLOC1S6,SRGAP3,KIF19,DMD,DNAH9,DYNC1I1,DPYSL2,DRD1,ABI1,DSCAM,WDPCP,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,EGR3,PLXNC1,IRAK4,TNK2,CERCAM,EMX2,PLEKHO1,DMTN,EPHA5,EPHB1,EPS8,ERBB2,ERBB4,APC2,ETV1,CEND1,F3,PTK2B,TUBB3,EFEMP1,DLC1,ATP8A1,RACK1,FKTN,FER,FGF1,OLFM1,FGF12,FGF13,FGFR1,FGR,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,AKAP3,DPYSL4,TBR1,NRG3,FYN,GAB1,CHL1,NCKAP1,GAP43,DISC1,DNER,GBX2,GCNT2,GFRA1,PPARGC1A,KIRREL3,LYVE1,GLI2,GPM6A,FUT10,GPER1,RAPGEF4,RFFL,GSN,KIF3A,RNF165,BVES,RABL2A,ATOH8,CELF3,HAS2,PADI2,NCKAP1L,HMGB1,HSP90AA1,MYLK2,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INPP5B,INSM1,TUBB2B,ITGA7,ITGAM,ITGAV,JAK1,JAK2,KCNH2,KIF2A,KIF5A,KIF5C,KIFC3,KIT,KLC1,KTN1,L1CAM,LAMA2,STMN1,MAG,MAP4,MAPT,MARK1,MATK,MATN2,MEF2C,KITLG,MITF,CCDC80,BLOC1S2,CTNNA3,MDGA1,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,NACA,NBL1,NCAM1,NEFH,NF1,NFE2L2,NODAL,NPY,DNHD1,NRCAM,NRDC,NTRK2,NTRK3,DDR2,OGDH,OLR1,OPA1,OPHN1,P2RY1,PAK3,PALM,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,ANLN,PIK3CD,PIK3R1,FXYD1,PLTP,PLXNB1,PLXNB3,SCHIP1,MBOAT7,EPB41L4B,FAT3,SH3KBP1,POU3F2,PKN2,PRKCZ,MAPK3,MAPK8,HYDIN,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,CCDC40,FEZF2,RDX,RET,RFX3,KIF7,MYH14,ROBO1,ROBO2,FBXW7,PRR5L,LRRK2,SOX8,AP1AR,SEMA6D,DRAXIN,SCN2B,SCN4B,SELL,KIF27,SGK1,KIF21A,SH3GL2,ARX,FERMT1,KIF16B,ASAP3,MYO18A,DOCK10,FUZ,SLC8A1,CCDC88A,ELMO2,SLIT1,SMARCA4,IFT122,KIF13A,PALLD,USP33,SCN3B,SOX1,KIF21B,SOX10,CLUAP1,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,KIF1B,NFASC,PBLD,CLASP2,MESP1,SST,MAPK8IP3,KANK1,SYNE2,PLCB1,ARC,TAC1,TACR1,SEMA4A,ROBO3,UNC5D,CNTN2,ADGRL3,WWC1,SATB2,CLASP1,TEK,TF,DNAH7,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,TMOD1,PARD3,TNNT1,TNR,TNS1,RBFOX2,TPM1,TPM2,TPM3,TPM4,ELP5,KCNE5,TMEFF2,SGK3,AMOT,UCHL1,FLRT2,VAV1,VAV2,WIPF1,P2RY12,WNT7A,KLC2,ZIC2,FMN2,NDRG4,DPYSL5,ZFAND5,DNALI1,LRP8,SCG2,SEMA3B,WIPF2,DNAH10,FZD3,DOCK8,RTN4,PAK5,VANGL2,FRMD6,AP3B2,SPATA13" GO: Biological Process GO:0008016 regulation of heart contraction 2.44E-11 2.39E-07 2.28E-09 2.23E-08 88 242 "ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CACNA2D2,CHGA,AKAP6,NOS1AP,HDAC4,DMD,DMPK,ABCC9,EDN1,EDN3,CACNG7,CACNG3,CACNG2,GAA,AHCYL1,GNAO1,BVES,HSP90AA1,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NOS1,NPPA,NPR2,PDE4B,PDE4D,PIK3R1,FXYD1,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,SIRT1,SPX,THRA,HEY2,TPM1,TRPC1,KCNE5" GO: Biological Process GO:0022603 regulation of anatomical structure morphogenesis 3.23E-11 3.17E-07 2.99E-09 2.92E-08 294 1128 "ABR,ACHE,FMNL2,ADD1,AXIN2,CDC7,ERMN,ADRB2,AP2A1,AP2A2,AGT,TBC1D14,SEMA6A,SEMA7A,FGD2,ANXA7,APC,EPB41L5,GAS7,LRRC4C,SHTN1,CPNE5,SEMA4G,ARHGDIA,ARRB2,CAPRIN2,DACT3,NUMB,ADGRB1,ADGRB2,ADGRB3,CFLAR,BMP7,CDK5R1,ARHGEF7,C5,LDLRAD4,CFAP410,CACNA1A,KALRN,HAP1,CAMK2B,KRIT1,FMNL3,ARHGEF1,SEPT7,CDC42,CDH2,ZMYM4,EVI5L,NOG,NUMBL,CHN1,CHRNB2,TAOK2,SLIT2,CPNE6,CLTC,NGEF,CCDC151,AKAP5,MAGED1,AATK,CSF1,TENM4,CSF1R,CSNK1E,CSNK1G3,SIPA1L1,CST3,PLXNA4,PPP1R16B,RIMS2,USP6NL,CX3CR1,CYBB,HDAC9,MYADM,TBC1D5,IST1,DAPK3,DBN1,DCC,ZEB2,MAGI2,PARD6A,MED12,DNM2,DPYSL2,DSCAM,DNM1L,FIS1,WDPCP,EDN1,EDNRA,SEMA3D,CELSR3,PLXNC1,EIF4G2,PLEKHO1,EPB41,EPB41L2,DMTN,EPS8,ERBB2,CDKL3,EYA1,F3,TBC1D16,PTK2B,DLC1,RACK1,SEC24B,FGF1,OLFM1,FGF13,FGFR1,BAIAP2,MAD2L2,FGR,CAMSAP1,SEMA6C,SEMA4D,FLT1,SYT3,PDLIM5,STAU2,TBR1,FYN,ERAP1,SYT17,DISC1,SEPT9,WASF3,GCNT2,PPARGC1A,TTBK1,FERMT2,GRIN1,CIT,GSN,KIF3A,IL1RAPL1,BVES,LINGO1,HAS2,HMGB1,HNRNPK,NKD1,RBPJ,KNDC1,ITGA7,ITPKA,JAK1,KIT,L1CAM,LIMS1,MAG,MAP2,MAP4,MAPT,MBP,MEF2C,MKLN1,CPNE9,MT3,RSPO2,NACA,NF1,NFE2L2,NODAL,NRCAM,NTRK2,NTRK3,ODF2,OMG,OPA1,PAK3,PALM,PDE3B,ENPP2,NLGN3,SSH1,SEMA5B,PLXNB1,PLXNB3,SH3KBP1,POU3F2,MED1,PPP3CA,PRKCB,MAPK7,MAPK9,FITM2,PROX1,RELN,PSMA6,QRICH1,PSMD13,PTK2,PTN,PTPRD,PTPRO,PTPRZ1,PID1,CEP97,FEZF2,RDX,RET,KCTD17,RNH1,MYH14,ROBO1,ROBO2,TMEM100,FBXW7,LRRK2,LGR4,SOX8,RXRA,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,SGK1,PPP1R9A,FUZ,ST6GAL1,NLGN1,ANKRD6,LIMS2,BTBD7,SLIT1,RIMS1,TNIK,SPP1,SPART,PBLD,CLASP2,MESP1,STOX1,EPB41L3,LARP4,TTBK2,PHLDB1,KANK1,SULF2,FGD4,ARC,SYT1,SYT4,SEMA4A,DDHD2,CNTN2,TCF4,CUX2,TCF7L2,CLASP1,SYNE1,OBSL1,TEK,DICER1,SIRT1,TGFBR3,HHIP,THBS4,TIAM1,TIE1,HEY1,DDHD1,BHLHB9,NR2E1,HEY2,TNR,TPM1,TTC3,UBC,AMOT,GORASP1,TBC1D15,WIPF1,WNT7A,CRB2,MFF,LRP8,RGMA,EVI5,SEMA3B,WIPF2,FZD3,RTN4,VANGL2,IFT88" GO: Biological Process GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 3.40E-11 3.33E-07 3.12E-09 3.04E-08 52 115 "ABAT,ADORA1,ADORA2A,ADRB2,NLGN4X,ARRB2,MTMR2,DGKI,CHRNA4,CHRNB2,NRXN1,RIMS2,DBN1,DLG4,DMPK,SHANK1,SEZ6,PTK2B,GABRA2,GABRA3,GABRA4,GABRB3,GABRG2,GLI2,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,GRIN2D,MEF2C,NLGN3,PPP3CA,PRKCZ,RELN,LRRK2,STX1B,ATXN1,PPP1R9A,NLGN1,RAB3GAP1,IGSF9B,RIMS1,SNCA,STX1A,CUX2,ZMYND8,WNT7A,CELF4,SLC17A7,NETO2,NETO1" GO: Biological Process GO:0055085 transmembrane transport 3.59E-11 3.52E-07 3.26E-09 3.18E-08 343 1356 "TTYH1,ABCF1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,ADD1,ADD2,ADD3,SLC12A5,SLC24A4,SLC44A5,AGT,PLA2G6,ABCD2,UNC79,KCNT1,DPP10,ANK2,ANK3,CNIH2,KCNAB2,SHROOM2,AQP4,AQP6,SLC7A14,CASK,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ATP6V1G2,ATP6V0A1,RIPK1,AZGP1,HCN2,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,SLC5A11,RGN,SLC16A4,P2RX6,SCARB1,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,NRXN1,SLC24A2,STOML1,ABCG2,CNGA3,AKAP7,AKAP6,SLC4A7,SLC4A8,COX4I1,MFSD4A,CRHBP,SLC32A1,ABCG1,SLC45A1,NOS1AP,CYBB,TCAF1,DAPK1,TOMM20,DBI,CNIH3,SV2B,SV2A,DLG3,DLG4,GRIN3A,DMD,SLC29A4,DNM2,SHANK1,SLC12A6,DPP6,SLC25A18,DRD1,ABCC5,ABCC9,EDN1,EDN3,EDNRA,EDNRB,SGK2,CACNG7,MFSD10,DMTN,KCNMB2,SLC43A2,NCALD,ABCA8,CACNG3,CACNG2,PTK2B,ATP8A1,TOMM40L,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,PCYOX1,ATP13A4,SLC37A3,TMEM175,HVCN1,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CAB39,AHCYL1,JPH4,PPARGC1A,GJB1,GLRB,KCNMB4,GPM6A,GPER1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,ADAMTS8,GRIN2C,GRIN2D,GRM7,IL1RAPL1,MFSD2A,SLC2A6,HSP90AA1,HTR2A,SLC6A17,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,SFXN5,GPR155,MEF2C,MYO5A,FXYD7,FXYD6,NOS1,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PIRT,PDPK1,SLC10A4,BEST3,ABCB1,NLGN3,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,SLC25A23,SLC36A4,PRKAB2,SLC26A11,RELN,SLC22A23,PTAFR,PEX2,PEX5,SLC25A48,SLC25A41,RASGRF1,RASGRF2,SLC6A15,SLC25A36,RNASEL,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,SCP2,ASIC4,SLC30A10,RASA3,SGK1,NLGN1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,PEX26,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,UNC80,SCN3B,MLC1,ABCC8,ARHGEF9,PLCB1,ARC,SLC37A2,ANO4,ACSL6,TPCN2,AZIN2,SLC19A3,ATP13A2,SLC44A1,LRRC8A,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,SGK3,UBC,BEST1,P2RY12,SLC13A3,KCNK12,SLC47A2,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,WNK1,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,TMEM63C,GJC2,SLC39A12,NETO2,SLC4A10,JPH3" GO: Biological Process GO:0010976 positive regulation of neuron projection development 3.84E-11 3.76E-07 3.45E-09 3.37E-08 99 286 "ACHE,KIDINS220,LRRC7,SEMA7A,APBB1,SHTN1,CPNE5,ARHGDIA,CAPRIN2,NUMB,BMP7,KALRN,HAP1,CAMK2B,CBFA2T2,NEURL1,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,FEZ1,RIMS2,IST1,DBN1,DCC,ZEB2,MAGI2,DMD,SHANK1,DSCAM,EIF4G2,ELAVL4,SEZ6,CDKL3,PTK2B,FGFR1,BAIAP2,SEMA4D,SYT3,NPTN,STAU2,FYN,SYT17,DISC1,ATP8A2,STMN2,RAPGEF1,NR3C1,PTPN5,IL1RAPL1,HNRNPK,NEGR1,ITPKA,L1CAM,MAPT,CPNE9,NFE2L2,NTRK2,NTRK3,OPA1,PAK3,PALM,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,RELN,PTN,PTPRD,PTPRZ1,RET,ROBO1,ROBO2,SGK1,PPP1R9A,CPEB3,NLGN1,TRIM67,RIMS1,SYT1,COBL,SYT4,ACSL6,CUX2,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,ZMYND8,VLDLR,NDRG4,PLPPR5,LRP8,RGMA" GO: Biological Process GO:0034762 regulation of transmembrane transport 4.71E-11 4.62E-07 4.20E-09 4.10E-08 145 473 "KCNH8,ASIC2,ACTN2,AGT,PLA2G6,DPP10,ANK2,ANK3,CNIH2,KCNAB2,CASK,ASPH,ATP1A2,ATP1B3,RIPK1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,KCNAB3,CACNA2D2,CBARP,CHRNA4,CLCN3,CLCN4,NRXN1,STOML1,AKAP7,AKAP6,CRHBP,NOS1AP,CYBB,TCAF1,DAPK1,DBI,CNIH3,DLG4,DMD,DNM2,SHANK1,DPP6,DRD1,EDN3,EDNRA,CACNG7,CACNG3,CACNG2,PTK2B,FGF12,FGF14,FHL1,HVCN1,CAB39,AHCYL1,JPH4,PPARGC1A,GPER1,GRIK1,GRIN1,GRIN2D,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNMA1,KCNN2,KCNQ2,KCNQ3,MEF2C,MYO5A,NOS1,NPPA,HCN1,OPRL1,P2RX7,KCNK10,PDE4B,PDE4D,PIRT,PDPK1,NLGN3,NALCN,PIK3C2A,FXYD1,RELN,PTAFR,RASGRF1,RASGRF2,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCP2,NLGN1,SLC8A1,SLN,SNCA,SCN3B,PLCB1,ARC,ACSL6,TPCN2,AZIN2,TRPC1,KCNE5,KCNK12,WNK1,KCNAB1,WNK3,WNK2,NETO2,JPH3" GO: Biological Process GO:1900006 positive regulation of dendrite development 4.93E-11 4.83E-07 4.35E-09 4.25E-08 42 84 "ACHE,CAPRIN2,NUMB,BMP7,KALRN,CAMK2B,NEURL1,NUMBL,AKAP5,DBN1,SHANK1,EIF4G2,ELAVL4,SEZ6,CDKL3,BAIAP2,STAU2,NR3C1,IL1RAPL1,HNRNPK,ITPKA,OPA1,PAK3,PALM,NLGN3,PACSIN1,RELN,PTPRD,PTPRZ1,SGK1,PPP1R9A,CPEB3,NLGN1,COBL,CUX2,OBSL1,CRTC1,TIAM1,BHLHB9,ZMYND8,VLDLR,LRP8" GO: Biological Process GO:0044087 regulation of cellular component biogenesis 5.32E-11 5.21E-07 4.66E-09 4.55E-08 227 829 "ASIC2,SLITRK1,ADD1,ADD2,AGT,TBC1D14,KIAA1324,PLA2G6,PPFIA1,APC,EPB41L5,SPTBN4,ATM,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,MTMR3,WASF1,LDLRAD4,HAP1,CBLN1,CCK,LDB2,NEURL1,SEPT7,CDC42,CDH2,EVI5L,CHGA,CHRNB2,SLIT2,RAB33A,NRXN3,NRXN1,CLU,CCDC151,PICK1,BAG4,CHD1L,GDA,CLIP3,SNCAIP,FEZ2,FEZ1,ARHGEF10,SLITRK5,PPP1R16B,USP6NL,MYADM,ARHGAP24,HDAC4,TBC1D5,DAPK3,DBN1,MAGI2,SACS,DNM2,SHANK1,PDCD6IP,DNAJB6,DNM1L,WDPCP,EDN1,SH3GLB1,ABI2,SORBS3,TENM1,PAN3,DMTN,EPHB1,EPS8,ERCC2,SH3YL1,TBC1D16,PTK2B,DLC1,RACK1,SEC24B,FER,BAIAP2,EVL,PDLIM5,STAU2,NCKAP1,IQGAP2,GAP43,SEPT9,INPP5K,ARFIP1,GFAP,PCDH17,PSRC1,GPM6A,GPM6B,STMN2,TPPP,RAPGEF1,GRIN1,GSN,NCKAP1L,ATXN2L,HMGB1,SYNPO,HSP90AA1,IRF8,SCIN,INSM1,LRRTM3,LRRTM1,KIT,LRRC4B,STMN1,LIMS1,MAP4,MAPT,MEF2C,MITF,DBNL,MDGA1,NCAM1,NTRK2,NTRK3,ODF2,OXTR,P2RX7,PAK3,PALM,ENPP2,TMOD2,NLGN3,SSH1,PIK3R1,PLXNB3,MAGEL2,LRRN3,PRKCZ,MAPK8,MAPK9,PROX1,BCAS3,PTK2,PEX5,CEP97,RAP1GAP,RDX,KCTD17,KIRREL1,ROBO2,LRRK2,SYNDIG1,ATAT1,CLIP1,STX1B,AP1AR,ATXN2,LRRTM4,FNIP1,SMPD3,SGK1,PPP1R9A,PPM1E,ASAP3,FUZ,AMBRA1,FHOD3,SLITRK3,NLGN1,CLSTN1,RAB3GAP1,SIRT2,NAPB,ATF7IP,SLIT1,CDK5RAP2,RIMS1,SNCA,PALLD,SPTAN1,SPTB,CLASP2,CLSTN2,TTBK2,PHLDB1,STX1A,KANK1,STXBP1,COBL,TAC1,TACR1,MLST8,TAL1,ADGRL3,CUX2,CLASP1,TEK,THRA,BHLHB9,TLR4,HEY2,TMOD1,TPM1,LRRC24,ZMYND8,TSC1,LRTM2,TMEFF2,AMOT,FLRT2,FLRT1,TBC1D15,WIPF1,WNT7A,RICTOR,TRIM9,FMN2,SPIRE1,PLPPR5,TFIP11,PMEPA1,EVI5,WIPF2,ACTR3B,SLC39A12,IFT88,CBLN2" GO: Biological Process GO:0021543 pallium development 5.56E-11 5.46E-07 4.83E-09 4.72E-08 69 175 "ASCL1,NCOA1,BBS2,NRP2,CDK5R1,CDK5R2,CDH2,ADGRG1,SLIT2,LHX2,AKAP5,SLC32A1,CNTNAP2,CX3CR1,ZEB2,DLX1,TRAPPC9,CDON,DRD1,EGFR,EMX2,EPHA5,EZH1,FGF13,FGFR1,FOXG1,TACC2,DISC1,GART,KIRREL3,DCLK2,FUT10,GRIN1,KIF3A,HNRNPK,HTR5A,KCNA1,AFDN,MDGA1,NEFH,NEUROD1,NF1,NPY,NTRK2,OGDH,PAX6,MBOAT7,POU3F2,PROX1,RELN,PTPRZ1,PEX5,FAT4,FEZF2,ROBO1,ATAT1,TRA2B,ARX,BCAN,BTBD3,SOX2,PLCB1,TACC1,DICER1,NR2E1,TSC1,VLDLR,LRP8,RTN4" GO: Biological Process GO:0098660 inorganic ion transmembrane transport 5.61E-11 5.50E-07 4.83E-09 4.72E-08 210 754 "TTYH1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,SLC12A5,SLC24A4,AGT,PLA2G6,KCNT1,DPP10,ANK2,ANK3,KCNAB2,SHROOM2,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V0A1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,KCNAB3,CACNA2D2,CBARP,ASIC3,CLCN3,CLCN4,SLC24A2,STOML1,CNGA3,AKAP7,AKAP6,SLC4A7,COX4I1,NOS1AP,DBI,GRIN3A,DMD,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN3,EDNRA,CACNG7,KCNMB2,CACNG3,CACNG2,PTK2B,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,PCYOX1,SLC37A3,TMEM175,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CAB39,JPH4,GLRB,KCNMB4,GPM6A,GPER1,GRIN1,CACFD1,ADAMTS8,GRM7,IL1RAPL1,HTR2A,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,TTYH2,MYO5A,NOS1,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PDPK1,BEST3,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,PRKAB2,SLC26A11,PTAFR,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,SCN3B,ABCC8,PLCB1,SLC37A2,ANO4,TPCN2,TRPC1,TRPC3,TRPM2,KCNE5,ANO5,BEST1,P2RY12,KCNK12,KCNT2,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,SLC17A7,KCNAB1,WNK3,WNK2,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0032412 regulation of ion transmembrane transporter activity 6.54E-11 6.42E-07 5.58E-09 5.45E-08 76 201 "ASIC2,ACTN2,AGT,PLA2G6,ANK2,ANK3,CNIH2,ASPH,ATP1A2,ATP1B3,RIPK1,CACNA1D,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,RGN,CBARP,CHRNA4,NRXN1,STOML1,AKAP7,AKAP6,CRHBP,NOS1AP,TCAF1,DAPK1,CNIH3,DLG4,DMD,DNM2,SHANK1,CACNG7,CACNG3,CACNG2,PTK2B,FGF12,FGF14,FHL1,CAB39,AHCYL1,JPH4,PPARGC1A,KCNJ11,MEF2C,MYO5A,NOS1,NPPA,HCN1,OPRL1,PDE4B,PDE4D,PIRT,NLGN3,FXYD1,RELN,PTAFR,RASGRF1,RASGRF2,KCNIP2,SCN2B,SCN4B,NLGN1,SLN,SCN3B,PLCB1,ARC,KCNE5,WNK1,KCNAB1,WNK3,WNK2,NETO2,JPH3" GO: Biological Process GO:0051963 regulation of synapse assembly 7.61E-11 7.46E-07 6.43E-09 6.28E-08 43 88 "ASIC2,SLITRK1,ADGRB1,ADGRB2,ADGRB3,CBLN1,CHRNB2,NRXN3,NRXN1,SLITRK5,EPHB1,PDLIM5,STAU2,GRIN1,LRRTM3,LRRTM1,LRRC4B,MEF2C,MDGA1,NTRK2,NTRK3,OXTR,NLGN3,LRRN3,PTK2,ROBO2,SYNDIG1,LRRTM4,PPP1R9A,SLITRK3,NLGN1,CLSTN1,SLIT1,CLSTN2,ADGRL3,CUX2,BHLHB9,LRRC24,LRTM2,FLRT2,FLRT1,WNT7A,CBLN2" GO: Biological Process GO:0061337 cardiac conduction 9.16E-11 8.98E-07 7.68E-09 7.50E-08 56 131 "AGT,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1G,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CACNA2D2,DMPK,ABCC9,CACNG7,CACNG3,CACNG2,AHCYL1,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,CTNNA3,FXYD7,FXYD6,NOS1,NPPA,NPR2,PDE4D,FXYD1,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SLC8A2,SLC8A1,SLC8A3,SCN3B,TRPC1,KCNE5" GO: Biological Process GO:0032409 regulation of transporter activity 9.56E-11 9.38E-07 7.95E-09 7.76E-08 81 221 "ASIC2,ACTN2,AGT,PLA2G6,ANK2,ANK3,CNIH2,ASPH,ATP1A2,ATP1B3,RIPK1,CACNA1D,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,RGN,SYNGR3,CBARP,CHRNA4,NRXN1,STOML1,AKAP7,AKAP6,CRHBP,NOS1AP,TCAF1,DAPK1,CNIH3,DLG4,DMD,DNM2,SHANK1,SGK2,CACNG7,CACNG3,CACNG2,PTK2B,FGF12,FGF14,FHL1,CAB39,AHCYL1,JPH4,PPARGC1A,KCNJ11,MEF2C,MYO5A,NOS1,NPPA,HCN1,OPRL1,PDE4B,PDE4D,PIRT,NLGN3,FXYD1,RELN,PTAFR,RASGRF1,RASGRF2,KCNIP2,SCN2B,SCN4B,SGK1,NLGN1,SLN,SNCA,SCN3B,PLCB1,ARC,KCNE5,SGK3,WNK1,KCNAB1,WNK3,WNK2,NETO2,JPH3" GO: Biological Process GO:0001508 action potential 9.65E-11 9.46E-07 7.95E-09 7.77E-08 58 138 "ANK2,ANK3,CNTNAP1,ATP1A1,ATP1A2,ATP2A2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CAMK2D,CHRNA4,CHRNB2,CNR1,AKAP7,AKAP6,NOS1AP,DMD,DPP6,DRD1,KCNMB2,FGF12,KCNMB4,GPER1,RAPGEF4,GRIA1,GRIK2,KCNA1,KCNA2,KCNB1,KCNC2,KCND2,KCNH2,KCNMA1,CTNNA3,NRCAM,HCN1,GPR88,NALCN,MYH14,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A1,SCN3B,TAC1,TACR1,TPCN2,KCNE5" GO: Biological Process GO:0060997 dendritic spine morphogenesis 9.75E-11 9.56E-07 7.97E-09 7.78E-08 28 45 "CAPRIN2,CDK5R1,KALRN,CAMK2B,SEPT7,NGEF,SIPA1L1,CTNND2,DBN1,DLG4,SHANK1,EPHA5,EPHB1,BAIAP2,PDLIM5,STAU2,ITPKA,PAK3,NLGN3,RELN,LRRK2,PPP1R9A,NLGN1,CUX2,TIAM1,BHLHB9,WNT7A,LRP8" GO: Biological Process GO:0031346 positive regulation of cell projection organization 1.20E-10 1.18E-06 9.71E-09 9.49E-08 118 367 "ACHE,KIDINS220,LRRC7,SEMA7A,APBB1,APC,SHTN1,CPNE5,ARHGDIA,CAPRIN2,NUMB,BMP7,ARHGEF7,KALRN,HAP1,CAMK2B,CBFA2T2,NEURL1,SEPT7,CDC42,NUMBL,SLIT2,CPNE6,QKI,CNR1,CNTN1,AKAP5,FEZ1,RIMS2,HDAC4,IST1,DBN1,DCC,ZEB2,MAGI2,DMD,DNM2,SHANK1,DSCAM,EIF4G2,TENM1,ELAVL4,SEZ6,CDKL3,PTK2B,EFEMP1,FGFR1,BAIAP2,SEMA4D,SYT3,NPTN,STAU2,FYN,NCKAP1,SYT17,DISC1,SEPT9,ATP8A2,GPM6A,STMN2,RAPGEF1,NR3C1,PTPN5,IL1RAPL1,HNRNPK,NEGR1,HSP90AA1,ITPKA,KIT,L1CAM,MAPT,CPNE9,NFE2L2,NTRK2,NTRK3,OPA1,P2RX7,PAK3,PALM,ENPP2,NLGN3,SERPINE2,PLXNB1,PLXNB3,PACSIN1,RELN,BCAS3,PTN,PTPRD,PTPRZ1,RET,KCTD17,ROBO1,ROBO2,SGK1,PPP1R9A,CPEB3,FUZ,NLGN1,TRIM67,RIMS1,TTBK2,SYT1,COBL,SYT4,ACSL6,CUX2,OBSL1,CRTC1,SIRT1,TIAM1,BHLHB9,ZMYND8,VLDLR,NDRG4,PLPPR5,LRP8,RGMA" GO: Biological Process GO:0048814 regulation of dendrite morphogenesis 1.21E-10 1.19E-06 9.74E-09 9.51E-08 43 89 "ACHE,CAPRIN2,NUMB,ADGRB3,CDK5R1,KALRN,CAMK2B,NUMBL,CHRNB2,NGEF,AKAP5,SIPA1L1,DBN1,CDKL3,BAIAP2,SEMA4D,PDLIM5,STAU2,GRIN1,CIT,IL1RAPL1,KNDC1,ITPKA,PAK3,NLGN3,PPP3CA,RELN,PTPRD,PTPRZ1,ROBO1,LRRK2,SGK1,PPP1R9A,NLGN1,TNIK,CUX2,SYNE1,OBSL1,TIAM1,BHLHB9,NR2E1,GORASP1,LRP8" GO: Biological Process GO:0048168 regulation of neuronal synaptic plasticity 1.33E-10 1.30E-06 1.06E-08 1.03E-07 34 62 "AGT,PPFIA3,CAMK2A,CAMK2B,SHISA7,NEURL1,DBN1,DLG4,DRD1,NPTN,GRIK1,GRIK2,GRIN1,GRM5,SHISA6,MYLK2,KCNJ10,KIT,NF1,RAB3A,RASGRF1,S100B,BCAN,SLC8A2,RAB3GAP1,RIMS1,SNCA,NCDN,ARC,SYP,CNTN2,VGF,NETO1,JPH3" GO: Biological Process GO:0021953 central nervous system neuron differentiation 1.37E-10 1.34E-06 1.08E-08 1.06E-07 75 200 "SPTBN4,ASCL1,ATP2B2,NRP2,CACNA1A,CBLN1,DCLK1,CHRNB2,SLIT2,NRXN1,CSF1R,CHD5,PLXNA4,DCC,ZEB2,DLX1,DRD1,OLIG2,EPHB1,ERBB4,CEND1,FGFR1,FOXG1,TBR1,GABRB1,NKX6-2,SALL3,DISC1,GBX2,GLI2,DCLK2,LINGO1,KNDC1,HES5,MAP2,MDGA1,NFIX,NKX2-2,NPY,NTRK2,OGDH,PAX6,POU3F4,PROX1,MDGA2,PTCH1,PTK2,PEX5,FEZF2,ROBO1,ROBO2,SALL1,DRAXIN,ATXN2,ARX,SLIT1,SMARCC2,FAIM2,SOX1,SOX2,SOX5,MYCBP2,ZC4H2,TAL1,UNC5D,CNTN2,AGTPBP1,SATB2,SZT2,DICER1,NR2E1,WNT7A,GDPD5,PRDM8,SLC4A10" GO: Biological Process GO:0060291 long-term synaptic potentiation 1.41E-10 1.38E-06 1.10E-08 1.08E-07 35 65 "CAMK2B,SLC24A2,CX3CR1,DBI,DRD1,PTK2B,NPTN,GFAP,PTPN5,HNRNPK,LRRTM1,NF1,NOS1,NRGN,NTRK2,NLGN3,SERPINE2,PRKCZ,RELN,PTN,RAB3A,RASGRF2,S100B,PPP1R9A,NLGN1,SLC8A2,SLC8A3,SHANK2,RIMS1,SNAP25,SNCA,STAU1,CRTC1,NR2E1,TNR" GO: Biological Process GO:0090066 regulation of anatomical structure size 1.59E-10 1.56E-06 1.24E-08 1.21E-07 160 544 "ASIC2,ACTN2,ADCY6,ADD1,ADD2,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,SEMA6A,OGT,SEMA7A,ANXA7,ALS2,SHTN1,SHROOM2,AQP4,AQP6,SEMA4G,SPTBN4,ARHGAP5,ATP1A2,ATP2B2,BBS2,CDK5R1,CACNA1G,WASF1,CBS,CD38,CFL2,CHGA,CHRM1,SLIT2,CLCN3,PICK1,BAG4,CPS1,AATK,PLXNA4,DOCK4,MYADM,IST1,DBN1,DCC,HP1BP3,DNM2,DPYSL2,DRD1,DSCAM,USH1C,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,EGFR,ABI2,PLXNC1,EIF4G2,TENM1,DMTN,KCNMB2,EPS8,CDKL3,MRVI1,PTK2B,FER,OLFM1,FGF13,BAIAP2,SEMA6C,EVL,SEMA4D,NCKAP1,IQGAP2,DISC1,ARFIP1,KCNMB4,GPER1,CIT,GSN,GUCY1A1,NCKAP1L,HMGCR,HSP90AA1,HTR2A,SCIN,KCNMA1,L1CAM,MAPT,DBNL,MT3,NOS1,NPPA,NRCAM,NTRK3,OMG,OXTR,P2RX7,P2RY1,PAK3,TMOD2,SSH1,SEMA5B,PIK3C2A,MAGEL2,PTAFR,PTK2,RAP1GDS1,RDX,RET,KIRREL1,LRRK2,AP1AR,SEMA6D,DRAXIN,SMPD3,PPP1R9A,FHOD3,SLC8A1,SLC12A2,SLC12A4,SLIT1,WDTC1,SPP1,SPTAN1,SPTB,RAP1GAP2,SPART,CLASP2,KANK1,TACR1,SEMA4A,MLST8,CNTN2,ATP13A2,SIRT1,TGFBR3,LRRC8A,TMOD1,TNR,TSC1,TSC2,AMOT,PLEKHH2,VAV1,VAV2,WIPF1,WNT7A,RICTOR,FMN2,SPIRE1,RGMA,SEMA3B,WIPF2,RTN4,ACTR3B" GO: Biological Process GO:0097061 dendritic spine organization 1.81E-10 1.77E-06 1.40E-08 1.36E-07 31 54 "CAPRIN2,CDK5R1,MTMR2,KALRN,CAMK2B,SEPT7,NGEF,PICK1,SIPA1L1,CTNND2,DBN1,DLG4,SHANK1,EPHA5,EPHB1,BAIAP2,PDLIM5,STAU2,ITPKA,PAK3,NLGN3,RELN,LRRK2,PPP1R9A,NLGN1,CUX2,TIAM1,BHLHB9,ZMYND8,WNT7A,LRP8" GO: Biological Process GO:0008366 axon ensheathment 2.03E-10 1.99E-06 1.54E-08 1.51E-07 53 123 "ANK2,CNTNAP1,PRX,MPDZ,MTMR2,MYRF,CDH2,CLU,QKI,GAL3ST1,TENM4,ARHGEF10,OLIG2,ERBB2,ERCC2,FGFR3,FYN,NKX6-2,WASF3,HES5,KCNJ10,LAMA2,MAG,MBP,ADAM22,MYO5A,NF1,OMG,CLDN11,PLP1,PMP22,FA2H,POU3F2,KLK6,SH3TC2,RXRA,RXRG,SCN2A,SCN8A,SLC8A3,SIRT2,NFASC,EPB41L3,ACSBG1,CNTN2,TCF7L2,TF,DICER1,PARD3,TSC1,UGT8,LGI4,ZNF24" GO: Biological Process GO:0007272 ensheathment of neurons 2.03E-10 1.99E-06 1.54E-08 1.51E-07 53 123 "ANK2,CNTNAP1,PRX,MPDZ,MTMR2,MYRF,CDH2,CLU,QKI,GAL3ST1,TENM4,ARHGEF10,OLIG2,ERBB2,ERCC2,FGFR3,FYN,NKX6-2,WASF3,HES5,KCNJ10,LAMA2,MAG,MBP,ADAM22,MYO5A,NF1,OMG,CLDN11,PLP1,PMP22,FA2H,POU3F2,KLK6,SH3TC2,RXRA,RXRG,SCN2A,SCN8A,SLC8A3,SIRT2,NFASC,EPB41L3,ACSBG1,CNTN2,TCF7L2,TF,DICER1,PARD3,TSC1,UGT8,LGI4,ZNF24" GO: Biological Process GO:0051588 regulation of neurotransmitter transport 2.40E-10 2.35E-06 1.81E-08 1.77E-07 39 78 "ASIC1,ADORA2A,ATP1A2,ATP2A2,CACNA1A,CACNA1B,CAMK2A,PNKD,SNCAIP,RIMS4,RIMS2,RIMS3,DRD1,EDN3,GFAP,KCNMB4,GPM6B,GPER1,GRIK5,GRM8,ICA1,NAT8L,MEF2C,NF1,NOS1,NTRK2,RAB3A,LRRK2,STX1B,PPP1R9A,NLGN1,RAB3GAP1,NAPB,RIMS1,SNCA,STX1A,STXBP1,SYT11,SYN1" GO: Biological Process GO:0051648 vesicle localization 2.46E-10 2.42E-06 1.84E-08 1.80E-07 92 267 "SYT13,DOC2A,AMPH,CNIH2,SHROOM2,CADPS,ATP2A2,BBS2,SYNJ1,CACNA1A,HAP1,CANX,SYT6,CDH2,NRXN1,MYRIP,SEC24C,RIMS4,RIMS2,SNPH,RIMS3,DCTN1,CNIH3,MAGI2,BLOC1S6,SEC16A,DNM1,TRAPPC9,DYNC1I1,DNM2,DPYSL2,SYT15,RASGRP1,STX2,F5,F8,SEC24B,FGF14,SYT3,DCTN2,SYT17,CPLX2,CPLX1,PCDH17,PCLO,GRIA1,GRIK5,KIF3A,MYLK2,C2CD4C,SYTL4,SYT9,BLOC1S2,MYO5A,MYO7A,OPHN1,P2RX7,NLGN3,PACSIN1,PRKCZ,SYTL2,RAB3A,LRRK2,SYNDIG1,STX1B,AP1AR,ITSN1,SH3GL2,NLGN1,SEC31A,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,KIF13A,CLASP2,STX1A,STXBP1,SYT11,SYN1,SYT1,ANKRD28,SYT4,SYT5,TCF7L2,CLASP1,GORASP1,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0022898 regulation of transmembrane transporter activity 2.52E-10 2.47E-06 1.87E-08 1.83E-07 76 206 "ASIC2,ACTN2,AGT,PLA2G6,ANK2,ANK3,CNIH2,ASPH,ATP1A2,ATP1B3,RIPK1,CACNA1D,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,RGN,CBARP,CHRNA4,NRXN1,STOML1,AKAP7,AKAP6,CRHBP,NOS1AP,TCAF1,DAPK1,CNIH3,DLG4,DMD,DNM2,SHANK1,CACNG7,CACNG3,CACNG2,PTK2B,FGF12,FGF14,FHL1,CAB39,AHCYL1,JPH4,PPARGC1A,KCNJ11,MEF2C,MYO5A,NOS1,NPPA,HCN1,OPRL1,PDE4B,PDE4D,PIRT,NLGN3,FXYD1,RELN,PTAFR,RASGRF1,RASGRF2,KCNIP2,SCN2B,SCN4B,NLGN1,SLN,SCN3B,PLCB1,ARC,KCNE5,WNK1,KCNAB1,WNK3,WNK2,NETO2,JPH3" GO: Biological Process GO:0016192 vesicle-mediated transport 2.56E-10 2.51E-06 1.89E-08 1.84E-07 372 1514 "SERPINA3,ABR,ACHE,SYS1,ACTN1,ACTN2,ADD1,CDC7,ADORA1,ADORA2A,SNX30,ADORA3,ESYT2,ADRB2,AP2A1,AP2A2,AP1B1,SNX32,OSBPL1A,TBC1D14,PLA2G6,SRPX,SYT13,DOC2A,AMPH,BIN1,ANK1,ANK2,ANK3,CNIH2,APLP1,DGKD,APOC1,APOC2,APP,SPTBN4,ARRB1,ARRB2,CADPS,ASGR1,MARCH3,DYNLL1,STX16,ATP2A2,BBS2,SYNJ1,BTK,MTMR2,AP1M1,CACNA1I,CACNA1G,RAB29,CDK5R2,CACNA1A,CALM1,KALRN,HAP1,CANX,SYT6,BRSK2,HIP1R,SPAG9,USP6,SCARB1,CD81,AP4M1,CDC42,EVI5L,COPB2,CBARP,CHGA,RAB3C,EPS15L1,CPNE6,ZFYVE9,CLCN3,NRXN1,COG1,CLU,CLTA,CLTB,CLTC,RAB26,PICK1,SEC31B,CRHBP,CLIP3,SEC24C,CSNK1E,CSNK1G3,RIMS4,CALY,RIMS2,RUBCN,USP6NL,GAPVD1,SNPH,ZFYVE16,KIF26A,TBC1D5,RIMS3,SCRN1,SIRPA,DNAJC6,DCTN1,ELMO1,CNIH3,MAGI2,BLOC1S6,SNAP91,SGSM2,RABGAP1L,SEC16A,DLG4,RAB39B,DNM1,TRAPPC9,DYNC1I1,DNM2,DOCK2,DPYSL2,ABI1,PDCD6IP,TOM1,DNM1L,GOLT1B,SYT15,RASGRP1,OPTN,GOLGA7,TNK2,CALCRL,DCTN4,DMTN,RABEPK,STX2,RAB9B,NCALD,RTN3,SIRPB1,F5,F8,TBC1D16,PRAM1,ATP8A1,RACK1,FCGR1A,FCGR1B,FCGR3A,FCGRT,SEC24B,FER,FGF14,BAIAP2,FGR,SCARA3,MEX3B,SEC23B,VTI1B,RGPD5,ANKFY1,SGIP1,SYT3,DCTN2,FOLR2,TMEM175,NBEA,ARFGAP2,ATP6V1H,ERGIC3,NSG2,NSG1,HHIPL1,AP4B1,TVP23A,FYN,MEGF10,DENND2A,BRPF3,NCKAP1,SYT17,ATP8A2,CPLX2,CPLX1,DNER,WASHC2A,GHR,LOXL3,GOLGB1,STON1,CECR2,GRK4,PCLO,RAPGEF4,GRIA1,GRIA2,GRIK5,GSN,KIF3A,PTPN5,IL1RAPL1,BVES,MFSD2A,AP4S1,HBA1,PACSIN2,NCKAP1L,HMGB1,GABARAPL2,HNRNPK,HP,HPR,HSP90AA1,SMAP1,IRF8,MYLK2,RAB41,IGF1,SCIN,LRRTM1,ITGAV,C2CD4C,KCNB1,KIF2A,KIF5A,KIT,KLC1,STXBP5,LAMP2,SYTL4,LYPLAL1,SYT9,LDLRAD3,LRP1B,MIA2,SCAMP5,DBNL,BLOC1S2,MSR1,NRBP2,SCG3,MYO5A,MYO6,MYO7A,NCAM1,CLEC9A,TBC1D25,OLR1,OPHN1,P2RX7,TREM2,ENPP2,PDPK1,NLGN3,PIK3C2A,PIK3CD,PIK3R1,SNX10,EPN1,LRP12,MAGEL2,PACSIN1,SH3KBP1,PPP3CB,RAB39A,PRKCG,MAPK3,MASP1,BCAS3,VPS13C,SYTL2,PTAFR,PTK2,PTX3,RAB3A,RAB5B,RAP1GAP,RDX,SGSM1,LRRK2,STX1B,AP1AR,ATXN2,SMPD3,PEAR1,COPZ1,ITSN1,SH3GL2,SH3GL3,KIF16B,MYO18A,NLGN1,SEC31A,RPH3A,EPN2,RAB3GAP1,SLC11A1,NAPB,ELMO2,LGI3,ARFGAP1,RIMS1,SNAP25,SNCA,KIF13A,LMBRD1,USP33,FNBP1,ERC1,SPTAN1,SPTB,CLASP2,FCHO1,MAPK8IP3,STX1A,STXBP1,SYT11,MLC1,JMJD6,VAMP1,VPS13A,PLCB1,SYN1,ARC,SYP,SYT1,ANKRD28,SYT4,SYT5,EXOC7,CNTN2,CLASP1,SYNE1,ATP13A2,TF,LEFTY2,AP4E1,AKTIP,ICAM5,PARD3,TMPRSS5,TSC2,TUB,UBE3A,GORASP1,VAV1,VAV2,VLDLR,TBC1D15,LMF1,VSNL1,WIPF1,LAT2,WNT7A,KLC2,TRIM9,FMN2,PLPP4,NDRG4,SPIRE1,LRP8,EVI5,LMAN2L,ADAMTS9,VPS35L,SNX27,WIPF2,MPPE1,PLD4,C12orf4,GOPC,AP3B2" GO: Biological Process GO:0098815 modulation of excitatory postsynaptic potential 2.64E-10 2.59E-06 1.93E-08 1.88E-07 24 36 "NLGN4X,MTMR2,NRXN1,RIMS2,DBN1,DLG4,DMPK,SHANK1,PTK2B,GRIN1,NLGN3,PRKCZ,RELN,LRRK2,STX1B,NLGN1,RIMS1,STX1A,CUX2,ZMYND8,WNT7A,CELF4,NETO2,NETO1" GO: Biological Process GO:0051056 regulation of small GTPase mediated signal transduction 2.76E-10 2.71E-06 2.01E-08 1.96E-07 99 295 "RALGAPA1,ABR,PLEKHG5,ADRA1B,ARHGAP20,OGT,CDC42BPA,FGD2,DGKZ,ALS2,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,ARHGEF7,MMD2,KALRN,CAMK2D,ARHGEF25,ARHGEF1,DGKI,ARHGEF2,CDC42,CDH2,ARHGAP33,ADGRG1,CHN1,CHN2,ARHGAP22,SLIT2,NGEF,ARHGEF6,CSF1,ARHGEF10,SIPA1L1,ARHGEF4,ARHGAP32,ARHGAP24,TIAM2,RHOBTB1,SRGAP3,CDON,DNM2,DOCK2,RASGRP1,FAM13A,RASA4,ERBB2,DLC1,FOXM1,PSD2,STAMBP,RAPGEF1,ARHGAP19,ARHGAP36,IGF1,INPP5B,ITPKB,ARHGAP12,KITLG,MYO9A,NF1,OCRL,OPHN1,MAPKAP1,RELN,PSD,IQSEC3,RAP1GAP,RASGRF1,RASGRF2,RDX,ARHGEF10L,ROBO1,RASA3,ITSN1,PREX2,ARHGEF40,TRIM67,ARHGAP26,IQSEC2,MCF2L2,RAP1GAP2,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,PSD3,ARHGEF12,ARHGAP9,TIAM1,TRIO,TSC2,AMOT,VAV1,VAV2,SPATA13" GO: Biological Process GO:0042552 myelination 3.37E-10 3.30E-06 2.43E-08 2.37E-07 52 121 "ANK2,CNTNAP1,PRX,MPDZ,MTMR2,MYRF,CDH2,CLU,QKI,GAL3ST1,TENM4,ARHGEF10,OLIG2,ERBB2,ERCC2,FGFR3,FYN,NKX6-2,WASF3,HES5,KCNJ10,LAMA2,MAG,MBP,ADAM22,MYO5A,NF1,OMG,PLP1,PMP22,FA2H,POU3F2,KLK6,SH3TC2,RXRA,RXRG,SCN2A,SCN8A,SLC8A3,SIRT2,NFASC,EPB41L3,ACSBG1,CNTN2,TCF7L2,TF,DICER1,PARD3,TSC1,UGT8,LGI4,ZNF24" GO: Biological Process GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 3.54E-10 3.47E-06 2.53E-08 2.48E-07 82 230 "DSCAML1,PCDH19,ALCAM,PCDH10,PCDHGB4,CADM3,CBLN1,CLDN10,CDH2,CDH8,CDH10,CDH18,NRXN1,NECTIN3,MYADM,DSCAM,CELSR3,CDHR1,NPTN,ATP2C1,CHL1,PCDH17,KIRREL3,PCDH11X,PTPRT,IL1RAPL1,CDH20,L1CAM,CD200,CLDN11,PCDHGC3,PCDH8,PCDH9,PKD1,PCDH18,SDK2,FAT3,MAPK7,DCHS2,PTPRD,PTPRG,FAT4,RET,ROBO1,ROBO2,NLGN1,CLSTN1,IGSF9B,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TRO,CADM1,PCDH20,CADM2,PCDH15" GO: Biological Process GO:0007010 cytoskeleton organization 4.95E-10 4.86E-06 3.52E-08 3.44E-07 296 1164 "ABR,ACTN1,ACTN2,FMNL2,ADD1,ADD2,ERMN,CC2D2A,TAOK1,SEMA6A,CEP126,MRTFA,CDC42BPA,ANK1,ANK3,FGD2,PPFIA1,CNTNAP1,APC,EPB41L5,GAS7,SHTN1,SHROOM2,SPTBN4,ARHGDIA,ARRB1,MARK4,DYNLL1,BBS2,CFLAR,CDK5R1,DST,WASF1,CFAP410,LURAP1,CAPN3,BRSK2,MAP7,PRC1,FMNL3,INA,NEURL1,ARHGEF2,SEPT7,CDC42,ZMYM4,CFL2,TAOK2,SLIT2,CLTC,CCDC151,CNN3,PICK1,BAG4,CDC42BPB,CRMP1,NCOR1,GDA,CLIP3,CSF1R,ARHGEF10,MICAL2,SIPA1L1,MYADM,KATNAL2,DAPK3,SIRPA,DBN1,ELMO1,KIAA0753,KIF19,SHANK1,DOCK2,DPYSL2,ABI1,PDCD6IP,DNAJB6,USH1C,WDPCP,EDN1,FRY,ABI2,SORBS3,TENM1,EML1,EPB41,EPB41L1,EPB41L2,DMTN,EPHA5,EPS8,APC2,KATNAL1,EYA1,TUBA1B,PTK2B,CORO2B,DLC1,ZMYND10,TESK2,FER,FGF13,BAIAP2,MAD2L2,FGR,CAMSAP1,CAP2,AGAP2,EVL,DCTN2,TACC2,SORBS1,ATP2C1,STAU2,TPPP3,BRSK1,ABLIM2,NEK6,NCKAP1,IQGAP2,DISC1,ATP8A2,INPP5K,WASF3,TUBGCP4,TUBA8,ARFIP1,GFAP,RND1,MAP7D2,DCLK2,PSRC1,GPM6B,EML4,CECR2,PCLO,STMN2,TPPP,CIT,GSN,PACSIN2,NCKAP1L,SYNPO,AGFG1,SMAP1,DOCK7,SCIN,ITPKA,JAK2,KIF2A,KIT,STMN1,MAP2,MAP4,MAP6,MAPT,MARK1,MEF2C,MID1,MKLN1,DBNL,BLOC1S2,MYH3,MYH6,NEFM,NEFH,CCDC13,NF1,NTRK3,NUMA1,OPHN1,P2RX7,PAK3,PALM,PAX6,PDGFRA,PDPK1,TMOD2,SSH1,ANLN,PIK3R1,CCSER2,PKD1,GPSM2,PLXNB1,MAGEL2,EPB41L4B,PACSIN1,SH3KBP1,PTPA,PRKCZ,MAPK3,MAPK8,FITM2,HYDIN,PROX1,PRPH,BCAS3,GDPD2,QRICH1,CNTLN,PTK2,SPDL1,PPP2R3C,CEP97,CCDC40,IQSEC3,RAP1GDS1,RDX,FIGN,MYH14,KIRREL1,MAP6D1,ATAT1,CLIP1,AP1AR,ATXN7,MRAS,SGK1,PPP1R9A,PPM1E,ASAP3,MYO18A,FHOD3,NLGN1,ABLIM3,SIRT2,CCDC88A,ELMO2,MAST1,CDK5RAP2,TTC17,LIMCH1,SNCA,PALLD,USP33,SON,TNIK,CLUAP1,MYCBP2,ARHGAP26,SPTAN1,SPTB,IQSEC2,CLASP2,EPB41L3,LARP4,SS18,ERBIN,CEP68,PHLDB1,KANK1,FGD4,SYNE2,ARC,COBL,TAC1,TACC1,TACR1,MTCL1,MLST8,CAMSAP2,CNTN2,CLASP1,SYNE1,OBSL1,FRYL,TEK,TF,DNAH7,DICER1,TMOD1,DAAM2,PARD3,TPM1,TSC1,TMEFF2,TUBB1,AMOT,UGT8,PLEKHH2,MICAL1,WIPF1,RICTOR,XPO1,FMN2,SPIRE1,STMN4,PCDH15,WIPF2,PAK5,ACTR3B,VANGL2,SLC39A12,IFT88,GAN" GO: Biological Process GO:1903522 regulation of blood circulation 5.06E-10 4.96E-06 3.57E-08 3.49E-07 108 334 "ASIC2,ADCY6,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CD38,CACNA2D2,CHGA,CHRM1,AKAP6,CPS1,NOS1AP,DOCK4,HDAC4,DMD,DMPK,DRD1,ABCC9,EDN1,EDN3,CACNG7,EGFR,KCNMB2,CACNG3,CACNG2,GAA,AHCYL1,KCNMB4,GNAO1,GPER1,BVES,HMGCR,HSP90AA1,HTR2A,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,KCNMA1,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NOS1,NPPA,NPR2,OXTR,P2RY1,PDE4B,PDE4D,PIK3R1,FXYD1,PTAFR,PTK2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,TACR1,SIRT1,SPX,THRA,HEY2,TPM1,TRPC1,KCNE5" GO: Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway 5.83E-10 5.71E-06 4.08E-08 3.99E-07 19 25 "APP,ATP1A3,CDK5R1,CAMK2A,GRIN3A,PTK2B,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,CPEB4" GO: Biological Process GO:0007264 small GTPase mediated signal transduction 6.35E-10 6.23E-06 4.42E-08 4.31E-07 168 588 "RALGAPA1,ABR,PLEKHG5,BRAP,ADRA1B,HACE1,BCAR3,ARHGAP20,OGT,CDC42BPA,FGD2,USP28,DGKZ,ALS2,SHTN1,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RASL11B,DOCK11,KSR1,ARHGEF7,RAB29,WASF1,MMD2,DIRAS1,KALRN,CAMK2D,ARHGEF25,KRIT1,ARHGEF1,DGKI,ARHGEF2,CDC42,CDH2,ARHGAP33,ADGRG1,CHM,CHN1,CHN2,RAB3C,ARHGAP22,SLIT2,RAB33A,RAB28,NGEF,RAB26,ARHGEF6,AATK,CSF1,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,DOCK4,ARHGAP32,ARHGAP24,ELMO1,TIAM2,RHOBTB1,SRGAP3,G3BP2,RAB39B,CDON,DNM2,DOCK2,EDNRA,RASGRP1,FAM13A,ABI2,RASA4,TNK2,RASGRP2,RAB9B,EPS8,ERBB2,DNAJC27,RASL12,DLC1,BAIAP2,AGAP2,AGAP3,FOXM1,PSD2,STAMBP,RASL10A,RAPGEF6,NCKAP1,IQGAP2,RUNDC3A,RND1,RAB30,RAB40B,RAPGEF4,RAPGEF1,RABL2A,ARHGAP19,ARHGAP36,RAB41,IGF1,DOCK7,KNDC1,INPP5B,ITPKB,ARHGAP12,SHC3,KITLG,DBNL,MYO9A,NF1,OCRL,OPHN1,MAPKAP1,RASGEF1B,RAB39A,DIRAS2,RELN,PSD,RAB3A,RAB5B,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RDX,ARHGEF10L,RIT2,RERGL,ROBO1,LRRK2,RTKN,MRAS,RASA3,ITSN1,DOCK10,PREX2,ARHGEF40,TRIM67,ARHGAP26,IQSEC2,MCF2L2,RAP1GAP2,RGL1,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,DOCK9,PSD3,ARHGEF12,ARHGAP9,ARL10,TIAM1,RASD2,TRIO,TSC2,AMOT,VAV1,VAV2,HRASLS,DOCK8,VANGL2,SPATA13" GO: Biological Process GO:0060047 heart contraction 7.50E-10 7.36E-06 5.18E-08 5.06E-07 93 276 "ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CDC42,CACNA2D2,CHGA,AKAP6,NOS1AP,HDAC4,DMD,DMPK,DNM1L,ABCC9,EDN1,EDN3,CACNG7,CACNG3,CACNG2,FGF12,GAA,AHCYL1,GNAO1,BVES,HSP90AA1,MYLK2,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NOS1,NPPA,NPR2,PDE4B,PDE4D,PIK3R1,FXYD1,RPS6KA2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,SIRT1,SPX,THRA,HEY2,TPM1,TRPC1,KCNE5" GO: Biological Process GO:0016079 synaptic vesicle exocytosis 7.76E-10 7.61E-06 5.32E-08 5.20E-07 42 90 "SYT13,DOC2A,CADPS,ATP2A2,SYNJ1,CACNA1A,SYT6,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SYT15,STX2,SYT3,SYT17,CPLX2,CPLX1,PCLO,GRIK5,C2CD4C,SYTL4,SYT9,P2RX7,SYTL2,RAB3A,LRRK2,STX1B,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,STX1A,STXBP1,SYT11,SYN1,SYT1,SYT4,SYT5,TRIM9" GO: Biological Process GO:0050770 regulation of axonogenesis 8.00E-10 7.85E-06 5.45E-08 5.32E-07 70 188 "ACHE,SEMA6A,SEMA7A,LRRC4C,SHTN1,SEMA4G,ARHGDIA,CDK5R1,CACNA1A,ARHGEF1,CDH2,CHN1,SLIT2,AATK,SIPA1L1,PLXNA4,IST1,DBN1,DCC,ZEB2,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,FGF13,SEMA6C,SEMA4D,TBR1,DISC1,GRIN1,LINGO1,L1CAM,MAG,MAP2,MAPT,MBP,MT3,NRCAM,NTRK2,NTRK3,OMG,SSH1,SEMA5B,PLXNB1,PLXNB3,POU3F2,PTK2,PTPRO,FEZF2,RET,ROBO1,ROBO2,SEMA6D,DRAXIN,SLIT1,SPP1,SPART,CLASP2,SEMA4A,CNTN2,TIAM1,TNR,WNT7A,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0051130 positive regulation of cellular component organization 8.41E-10 8.25E-06 5.69E-08 5.56E-07 316 1263 "ABR,ASIC2,ACHE,ACTN2,SLITRK1,ADD1,AXIN2,ADRB2,KIDINS220,AGT,KIAA1324,PLA2G6,LRRC7,BIN1,OGT,DPP10,ANK1,ANK3,SEMA7A,C6orf89,APBB1,APC,EPB41L5,APOC2,SHTN1,CPNE5,MIER1,ARHGDIA,ARRB1,ARRB2,CAPRIN2,NUMB,DYNLL1,ATM,EIF4G3,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,CDK5R1,SYNJ1,ARHGEF7,WASF1,KALRN,HAP1,CAMK2B,CBLN1,CCK,CBFA2T2,NEURL1,SEPT7,CDC42,CDH2,NUMBL,CFL2,SLIT2,CPNE6,NRXN3,NRXN1,CLU,QKI,NIPBL,CNR1,PICK1,CNTN1,AKAP5,BAG4,CHD1L,SH2B1,NCOR1,GDA,CLIP3,FEZ1,ARHGEF10,SLITRK5,CALY,RIMS2,MYADM,TCAF1,FRMPD4,HDAC4,PHF19,TBC1D5,IST1,SIRPA,DBN1,DCC,ZEB2,MAGI2,DMD,DNM2,SHANK1,DOCK2,DPP6,PDCD6IP,DSCAM,DNM1L,FIS1,EDN1,EDN3,SH3GLB1,ABI2,EIF4G2,SORBS3,TENM1,ELAVL4,PAN3,DMTN,SEZ6,EPHB1,ERBB2,ERCC2,CDKL3,SIRPB1,PTK2B,EFEMP1,ATP8A1,RACK1,FCGR1A,FER,OLFM1,FGFR1,BAIAP2,MEX3B,EVL,SEMA4D,ANKFY1,SGIP1,SYT3,SORBS1,ZBED3,APOPT1,NPTN,PRELID3A,STAU2,OGA,FYN,NCKAP1,IQGAP2,SYT17,DISC1,SEPT9,ATP8A2,GCNT2,ARFIP1,PPARGC1A,PSRC1,GPM6A,GPR26,GPER1,STMN2,TPPP,RAPGEF1,NR3C1,GSN,KIF3A,PTPN5,IL1RAPL1,HAS2,NCKAP1L,SYNPO,HNMT,HNRNPK,HPCA,NEGR1,HSPA1L,HSP90AA1,IRF8,IGF1,SCIN,LRRTM3,LRRTM1,ITGAV,ITPKA,KCNB1,KCNN3,KIT,L1CAM,LRRC4B,LIG4,LIMS1,PAXBP1,MAPT,MITF,CPNE9,MYBPC1,NAP1L2,NEUROD2,NFE2L2,NOS1,NTRK2,NTRK3,DDR2,OPA1,OXTR,P2RX7,TREM2,PAK3,PALM,ENPP2,PDPK1,ZDHHC8,NLGN3,SERPINE2,PIK3R1,PLXNB1,PLXNB3,MAGEL2,PACSIN1,LRRN3,PPP3CC,MAPK3,MAPK8,MAPK9,PROX1,RELN,BCAS3,PTK2,PTN,PTPRD,PTPRZ1,PTX3,RAP1GAP,RET,KCTD17,ROBO1,KIRREL1,ROBO2,FBXW7,SYNDIG1,ATAT1,CLIP1,AP1AR,LRRTM4,FNIP1,ELMOD1,SFPQ,SGK1,PPP1R9A,PPM1E,CPEB3,FUZ,AMBRA1,SLITRK3,NLGN1,CLSTN1,ABLIM3,RAB3GAP1,SIRT2,TRIM67,SLC11A1,TET1,SLN,RIMS1,SNCA,PALLD,CLASP2,CLSTN2,TTBK2,PHLDB1,PLCB1,SYT1,COBL,SYT4,TAC1,TACR1,MTCL1,DDHD2,MLST8,TAL1,ADGRL3,ACSL6,CUX2,TCF7L2,CLASP1,SYNE1,OBSL1,CRTC1,TEK,TF,SIRT1,TIAM1,DDHD1,BHLHB9,TLR4,PARD3,TP53BP2,TPM1,WBP2,LRRC24,ZMYND8,TSC1,LRTM2,TUB,AMOT,FLRT2,FLRT1,VLDLR,WIPF1,WNT7A,RICTOR,FMN2,NDRG4,CRB2,SPIRE1,PLPPR5,MFF,LRP8,RGMA,HPS4,WIPF2,WNK3,NELFE,ACTR3B,CBLN2" GO: Biological Process GO:0051240 positive regulation of multicellular organismal process 9.02E-10 8.85E-06 6.06E-08 5.92E-07 389 1610 "ABAT,ASIC2,ACHE,SLITRK1,ADD1,AXIN2,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,KIDINS220,BEND6,AGT,PLA2G6,C1QTNF1,C1QTNF3,LRRC7,SEMA6A,BIN1,OGT,SEMA7A,APBB1,EPB41L5,GPAM,APOC2,SHTN1,CPNE5,SPTBN4,ARHGDIA,ARNTL,ASCL1,ASPA,CAPRIN2,PTCH2,BRINP2,NCOA1,NUMB,ATP1A1,ATP2A2,RIPK1,ADGRB1,ADGRB2,ADGRB3,BBS2,HCN2,NRP2,PROM1,BMP7,BMPR1B,SYNJ1,BTK,C5,MYRF,IL33,MMD2,LURAP1,KALRN,HAP1,CAMK2B,CAMK2D,SPAG9,CBLN1,USP2,CD86,CBFA2T2,SCARB1,CD38,NEURL1,ARHGEF2,CDC42,LRRFIP1,NOG,NUMBL,CACNA2D2,GPR37L1,CHGA,SLIT2,CPNE6,NRXN3,NRXN1,CLU,QKI,NIPBL,CNR1,CNTN1,AKAP6,AKAP5,MAGED1,CPS1,CSF1,TENM4,CSF1R,RGS6,FEZ1,SOCS5,SLITRK5,PPP1R16B,CTH,PUM1,RIMS2,CX3CR1,NOS1AP,CYBB,HDAC9,IST1,BRINP1,DBN1,DCC,DCT,ZEB2,MAGI2,DMD,CDON,SHANK1,DSCAM,EDN1,EDN3,EDNRA,EDNRB,HEYL,RASGRP1,EBI3,EGFR,EGR3,EIF4G1,EIF4G2,ELAVL4,OLIG2,DMTN,SEZ6,EPHB1,ERBB4,CDKL3,TLR7,F3,PTK2B,RACK1,PRMT5,SLC9B2,FGF1,OLFM1,FGFR1,FGFR3,BAIAP2,FGR,SUCO,FOXG1,AGAP2,FOXO3,SEMA4D,FLT1,SYT3,TRIM16,NPTN,CELF1,DLL3,STAU2,FYN,NKX6-2,GALR1,ERAP1,SYT17,DISC1,ATP8A2,INPP5K,WASF3,GCNT2,GFAP,GHR,PPARGC1A,MALT1,CRCP,GLI2,KDM2B,GNAS,GPM6B,GPER1,RAPGEF4,STMN2,RAPGEF1,NR3C1,GRM5,PTPN5,IL1RAPL1,ATOH8,IRAK3,HAS2,NCKAP1L,HMGB1,HMGCR,HNRNPK,NEGR1,HSP90AA1,SMAP1,HTR2A,IRF8,IFI16,MYLK2,IGF1,RBPJ,SCIN,IL6R,IL6ST,IL12A,BRINP3,LRRTM3,LRRTM1,ITPKA,ITPKB,JAK1,JAK2,KCNMA1,KIT,L1CAM,LRRC4B,LIG4,FGFBP3,SMAD1,MAG,MAPT,MEF2C,KITLG,SCAMP5,CPNE9,NACA,NAP1L2,NBL1,NCAM1,NELL1,NEUROD1,NEUROD2,NFE2L2,NKX2-2,NODAL,NOS1,NPPA,CLEC9A,NRCAM,NTRK2,NTRK3,DDR2,NUCB2,OPA1,OPRL1,OXTR,P2RX7,P2RY1,PAK3,PALM,PAX6,PDCD2,PDE3A,PDE4B,PDE4D,ENPP2,PENK,NLGN3,SERPINE2,PIK3R1,PLXNB1,PLXNB3,EPB41L4B,PACSIN1,POLR2F,POU3F2,MED1,LRRN3,PPP3CA,PRKCB,PRKCZ,MAPK8,MAPK9,PROX1,RELN,BCAS3,SYTL2,GDPD2,PTAFR,PTCH1,PTK2,PTN,PTPRD,PTPRZ1,PEX5,PPP2R3C,FEZF2,RET,RFX3,ROBO1,ROBO2,TMEM100,LGR4,SYNDIG1,SOX8,SALL1,ATXN1,LRRTM4,IL17RB,SEC14L1,SOX6,SGK1,PPP1R9A,ARX,CPEB3,SLITRK3,NLGN1,CLSTN1,SLC8A1,SIRT2,TRIM67,SLC11A1,SMARCD3,RIMS1,SCN3B,SOX2,SOX5,SOX10,SOX11,ZHX3,SPP1,KDM4C,CLASP2,CLSTN2,MESP1,STOX1,MAPK8IP3,PHLDB1,SULF2,PLCB1,SYT1,COBL,SYT4,TAC1,TACR1,TAL1,ADGRL3,ACSL6,VWC2,TCF4,CUX2,TCF7L2,ZEB1,TCF12,CLASP1,OBSL1,PUM2,CRTC1,TEK,TF,DICER1,SIRT1,ZFPM2,TIAM1,HEY1,BHLHB9,TLR4,NR2E1,HEY2,PARD3,TNR,TPM1,IL34,NR2C2,LRRC24,TRPC3,ZMYND8,LRTM2,CADM1,AMOT,FLRT2,FLRT1,VLDLR,NSD2,WNT7A,XRCC4,ZIC2,NDRG4,CRB2,ZBTB16,POLR3H,PLPPR5,LRP8,RGMA,GDPD5,FZD3,RTN4,NLRP3,CBLN2" GO: Biological Process GO:0060341 regulation of cellular localization 1.01E-09 9.93E-06 6.75E-08 6.60E-07 348 1416 "ABAT,ABR,ASIC1,ACHE,ACTN2,ADCY5,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,SYT13,DOC2A,OGT,DPP10,ANK2,ANK3,CNIH2,PPFIA1,APBB1,KCNAB2,APC,GPAM,MADD,ARNTL,ARRB1,RGS20,CADPS,PDE8B,ASPH,DACT3,NUMB,DYNLL1,ATP1A2,ATP2A2,BARD1,BID,BMP7,CDK5R1,SYNJ1,ARHGEF7,MTMR2,CACNA1I,CACNA1G,C5,RAB29,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALM1,KALRN,HAP1,CAMK2A,CAMK2D,CAPN3,SYT6,BRSK2,CCK,CCKBR,CD38,CDC42,CDH2,DCLK1,CACNA2D2,CBARP,CHGA,CHRM1,CHRNA4,RAB3C,CHRNB2,NRXN1,CLTC,HECTD1,MAP4K4,RAB26,CNR1,AKAP6,CABP1,AKAP5,BAG4,MYRIP,PNKD,CLOCK,CRHBP,CRY2,CLIP3,SNCAIP,CSF1R,CSNK1E,RIMS4,APPL1,RIMS2,TCAF1,RIMS3,DBI,DBN1,B3GAT3,C2CD2L,MAGI2,PARD6A,G3BP2,DMD,DNM1,DPP6,DPYSL2,DRD1,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EDNRA,SYT15,RASGRP1,SIDT2,SH3GLB1,EGFR,TENM1,DMTN,EPHA5,ERBB2,ERBB4,APC2,DNAJC27,TLR7,REEP2,PTK2B,PRAM1,RACK1,SEC24B,FER,FGF14,FGFR1,FGR,VTI1B,SYT3,SORBS1,ZBED3,TRIM16,NPTN,PRELID3A,OGA,FYN,GABBR1,JPH4,GALR1,SYT17,INPP5K,CPLX2,CPLX1,GCK,ARFIP1,GDF9,PCDH17,GLUL,OS9,KCNMB4,DCLK2,GNAS,GPM6B,GPR26,GPER1,PCLO,RAPGEF4,GRIK5,NR3C1,GRM7,GRM8,GSN,KIF3A,PTPN5,IL1RAPL1,KAT7,BVES,HRH3,HMGB1,HMGCR,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,HTR2A,ICA1,MYLK2,IGF1,C2CD4C,JAK2,KCNA2,KCNB1,KCNC2,KCNJ11,KCNN3,IPO5,STXBP5,SYTL4,NAT8L,MAOB,MAPT,LYPLAL1,SYT9,MDFI,MEF2C,SCAMP5,MXI1,MYBPC1,MYO5A,MYT1,HNRNPM,NCAM1,NEFH,NELL2,NEUROD1,NF1,NNAT,NODAL,NOS1,CLEC9A,NTRK2,NUCB1,NUCB2,OGG1,OXTR,P2RX7,P2RY1,TREM2,PAX6,PDE1C,PDE2A,PDE3B,PDE4D,PDPK1,PFKFB2,ZDHHC8,NLGN3,PIK3R1,PKD1,PLCD1,MED1,PPM1B,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PKIA,PRKCB,PRKCZ,MAPK3,MAPK7,MAPK8,BCAS3,SYTL2,PTAFR,PTN,RAB3A,PID1,SH3TC2,RDX,RFX3,FBXW7,LRRK2,LGR4,WLS,STX1B,SCP2,SMPD3,ELMOD1,IL17RB,SCG5,PPP1R9A,MYO18A,SYBU,NLGN1,ABLIM3,RPH3A,SLC8A1,RAB3GAP1,SIRT2,CDK5RAP3,NAPB,LGI3,RIMS1,SNAP25,SNCA,SOX11,PBLD,CLASP2,TTBK2,STX1A,KANK1,SULF2,STXBP1,SYT11,MLC1,ABCC8,PLCB1,SYN1,SYT1,SYT4,ASTN2,SYT5,TAC1,TACR1,MTCL1,WWC1,FBXW11,TCF7L2,CLASP1,TEK,ATP13A2,SIRT1,THRA,TIAM1,TLR4,PARD3,TP53BP2,ZNF384,TRH,STXBP4,TRPC1,TRPC3,TRPM2,ZMYND8,CADM1,VSNL1,WIPF1,P2RY12,XPO1,ZIC1,TRIM9,NDRG4,REEP1,MFF,HPS4,WNK3,C12orf4,GOPC,RTN4,NLRP3,AAAS,JPH3" GO: Biological Process GO:0098662 inorganic cation transmembrane transport 1.16E-09 1.13E-05 7.66E-08 7.48E-07 185 667 "TTYH1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,SLC12A5,SLC24A4,AGT,PLA2G6,KCNT1,DPP10,ANK2,ANK3,KCNAB2,SHROOM2,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V0A1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,KCNAB3,CACNA2D2,CBARP,ASIC3,SLC24A2,STOML1,CNGA3,AKAP7,AKAP6,SLC4A7,COX4I1,NOS1AP,DBI,GRIN3A,DMD,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN3,EDNRA,CACNG7,KCNMB2,CACNG3,CACNG2,PTK2B,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,TMEM175,ATP6V1H,ATP2C1,CAB39,JPH4,KCNMB4,GPM6A,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MYO5A,NOS1,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PDPK1,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,PRKAB2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,SCN3B,ABCC8,PLCB1,TPCN2,TRPC1,TRPC3,TRPM2,KCNE5,P2RY12,KCNK12,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC17A7,KCNAB1,WNK3,WNK2,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0003015 heart process 1.41E-09 1.39E-05 9.29E-08 9.08E-07 93 279 "ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CDC42,CACNA2D2,CHGA,AKAP6,NOS1AP,HDAC4,DMD,DMPK,DNM1L,ABCC9,EDN1,EDN3,CACNG7,CACNG3,CACNG2,FGF12,GAA,AHCYL1,GNAO1,BVES,HSP90AA1,MYLK2,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NOS1,NPPA,NPR2,PDE4B,PDE4D,PIK3R1,FXYD1,RPS6KA2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,SIRT1,SPX,THRA,HEY2,TPM1,TRPC1,KCNE5" GO: Biological Process GO:0043270 positive regulation of ion transport 1.74E-09 1.71E-05 1.14E-07 1.11E-06 94 284 "ABAT,ASIC2,ACTN2,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AGT,PLA2G6,ANK2,ANK3,CASK,ARRB2,ASPH,ATP1B3,ATP2B2,CACNA1D,CACNA2D1,CACNB2,CALM1,HAP1,CAMK2A,CAPN3,CCK,RGN,CHRM1,CHRNA4,CHRNB2,CNTN1,AKAP7,AKAP6,AKAP5,NOS1AP,TCAF1,DBI,DMD,DNM2,DPP6,DPYSL2,DRD1,EDN1,EDN3,EDNRA,SGK2,ATP8A1,FGF12,FGF14,FHL1,OGA,GABBR1,AHCYL1,ATP8A2,GNAS,MCHR1,GPER1,GRIK1,NR3C1,KCNC1,KCNC2,KCNH2,KCNJ11,NAT8L,NOS1,NPPA,HCN1,P2RX7,P2RY1,PIRT,PDPK1,NLGN3,FXYD1,MAPK9,RELN,PTAFR,SCN4B,SGK1,SLC6A1,RAB3GAP1,SNCA,SCN3B,ABCC8,PLCB1,ARC,ACSL6,TRH,TRPC1,TRPC3,KCNE5,SGK3,P2RY12,WNK1,WNK3,WNK2,RTN4" GO: Biological Process GO:0021782 glial cell development 2.00E-09 1.96E-05 1.30E-07 1.27E-06 41 89 "ADORA2A,AGT,PRX,ASCL1,MYRF,CLU,PICK1,TENM4,ARHGEF10,DMD,MED12,DRD1,EGFR,ERCC2,FGFR3,NKX6-2,WASF3,GFAP,GSN,HES5,ITGAM,KCNJ10,LAMA2,ADAM22,MT3,NF1,NKX2-2,OMG,PLP1,FA2H,POU3F2,SH3TC2,SIRT2,SOX11,CNTN2,TCF7L2,DICER1,TLR4,PARD3,LGI4,PRDM8" GO: Biological Process GO:0046928 regulation of neurotransmitter secretion 2.07E-09 2.03E-05 1.34E-07 1.31E-06 33 64 "ASIC1,ADORA2A,ATP2A2,CACNA1A,CACNA1B,CAMK2A,PNKD,SNCAIP,RIMS4,RIMS2,RIMS3,EDN3,KCNMB4,GPER1,GRIK5,GRM8,ICA1,MEF2C,NF1,NTRK2,RAB3A,LRRK2,STX1B,PPP1R9A,NLGN1,RAB3GAP1,NAPB,RIMS1,SNCA,STX1A,STXBP1,SYT11,SYN1" GO: Biological Process GO:0060627 regulation of vesicle-mediated transport 2.99E-09 2.93E-05 1.92E-07 1.87E-06 147 508 "ABR,ACTN2,ADD1,ADORA3,TBC1D14,PLA2G6,SYT13,DOC2A,BIN1,CNIH2,APOC1,APOC2,ARRB1,ARRB2,CADPS,ATP2A2,SYNJ1,MTMR2,CACNA1I,CACNA1G,CDK5R2,CACNA1A,HAP1,SYT6,USP6,SCARB1,EVI5L,CBARP,RAB3C,RAB26,PICK1,CLIP3,RIMS4,CALY,RIMS2,RUBCN,USP6NL,SNPH,ZFYVE16,TBC1D5,RIMS3,SIRPA,DNAJC6,MAGI2,SNAP91,SGSM2,RABGAP1L,DLG4,DNM1,DNM2,DOCK2,PDCD6IP,SYT15,TNK2,SIRPB1,TBC1D16,PRAM1,RACK1,FCGR1A,SEC24B,FER,FGF14,FGR,MEX3B,ANKFY1,SGIP1,SYT3,SYT17,CPLX2,CPLX1,STON1,PCLO,RAPGEF4,GRIK5,KIF3A,PTPN5,IL1RAPL1,BVES,PACSIN2,NCKAP1L,HMGB1,HNRNPK,SMAP1,LRRTM1,ITGAV,C2CD4C,KCNB1,STXBP5,SYTL4,LYPLAL1,SYT9,SCAMP5,MYO5A,NCAM1,TBC1D25,OPHN1,PDPK1,PACSIN1,PRKCG,MAPK3,SYTL2,PTAFR,PTK2,PTX3,RAB3A,RAB5B,RAP1GAP,RDX,SGSM1,LRRK2,STX1B,ATXN2,SMPD3,SH3GL2,NLGN1,RPH3A,EPN2,RAB3GAP1,SLC11A1,NAPB,LGI3,ARFGAP1,RIMS1,SNCA,CLASP2,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,CLASP1,SYNE1,ATP13A2,TF,PARD3,TSC2,TUB,TBC1D15,VSNL1,TRIM9,NDRG4,EVI5,C12orf4,GOPC" GO: Biological Process GO:0032535 regulation of cellular component size 3.21E-09 3.15E-05 2.04E-07 2.00E-06 116 377 "ACTN2,ADD1,ADD2,SEMA6A,OGT,SEMA7A,ANXA7,ALS2,SHTN1,SHROOM2,AQP4,AQP6,SEMA4G,SPTBN4,ARHGAP5,ATP2B2,CDK5R1,WASF1,CFL2,SLIT2,CLCN3,PICK1,BAG4,AATK,PLXNA4,MYADM,IST1,DBN1,DCC,HP1BP3,DNM2,DPYSL2,DSCAM,USH1C,EDN1,SEMA3D,ABI2,PLXNC1,EIF4G2,TENM1,DMTN,EPS8,CDKL3,PTK2B,FER,OLFM1,FGF13,BAIAP2,SEMA6C,EVL,SEMA4D,NCKAP1,IQGAP2,DISC1,ARFIP1,CIT,GSN,NCKAP1L,HSP90AA1,SCIN,KCNMA1,L1CAM,MAPT,DBNL,MT3,NRCAM,NTRK3,OMG,P2RX7,PAK3,TMOD2,SSH1,SEMA5B,MAGEL2,RDX,RET,KIRREL1,AP1AR,SEMA6D,DRAXIN,PPP1R9A,FHOD3,SLC12A2,SLC12A4,SLIT1,WDTC1,SPP1,SPTAN1,SPTB,RAP1GAP2,SPART,CLASP2,KANK1,SEMA4A,MLST8,CNTN2,ATP13A2,LRRC8A,TMOD1,TNR,TSC1,TSC2,AMOT,PLEKHH2,VAV1,VAV2,WIPF1,WNT7A,RICTOR,FMN2,SPIRE1,RGMA,SEMA3B,WIPF2,RTN4,ACTR3B" GO: Biological Process GO:0098655 cation transmembrane transport 3.33E-09 3.27E-05 2.11E-07 2.06E-06 199 738 "TTYH1,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,SLC12A5,SLC24A4,AGT,PLA2G6,KCNT1,DPP10,ANK2,ANK3,KCNAB2,SHROOM2,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V0A1,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,P2RX6,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRNA4,CHRNB2,SLC24A2,STOML1,CNGA3,AKAP7,AKAP6,SLC4A7,COX4I1,NOS1AP,DBI,GRIN3A,DMD,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN3,EDNRA,CACNG7,KCNMB2,CACNG3,CACNG2,PTK2B,ATP8A1,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,ATP13A4,TMEM175,ATP6V1H,ATP2C1,CAB39,JPH4,KCNMB4,GPM6A,GPER1,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,HTR2A,ITGAV,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MYO5A,NOS1,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PIRT,PDPK1,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,SLC36A4,PRKAB2,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC30A10,RASA3,SLC6A7,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,SCN3B,ABCC8,PLCB1,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,KCNE5,P2RY12,KCNK12,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,TMEM63C,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0060996 dendritic spine development 3.36E-09 3.30E-05 2.11E-07 2.07E-06 40 87 "SLC12A5,CAPRIN2,CDK5R1,KALRN,CAMK2B,NEURL1,SEPT7,NGEF,SIPA1L1,CTNND2,DBN1,DLG4,SHANK1,EIF4G2,EPHA5,EPHB1,ACSL4,BAIAP2,PDLIM5,STAU2,DISC1,NR3C1,HNRNPK,ITPKA,MEF2C,GIT1,PAK3,PALM,NLGN3,RELN,LRRK2,PPP1R9A,CPEB3,NLGN1,CUX2,TIAM1,BHLHB9,ZMYND8,WNT7A,LRP8" GO: Biological Process GO:0006812 cation transport 3.56E-09 3.50E-05 2.23E-07 2.18E-06 280 1110 "TTYH1,ABAT,KCNH8,ASIC2,ASIC1,ACTN2,SLC25A25,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRB2,SLC24A4,SLC44A5,AGT,PLA2G6,KCNT1,DPP10,ANK1,ANK2,ANK3,KCNAB2,CACHD1,SHROOM2,CASK,SPTBN4,ARRB2,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,HCN2,BTK,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SLC25A14,CAPN3,CCKBR,SLC5A11,RGN,P2RX6,KCNAB3,CACNA2D2,CBARP,ASIC3,CHRNA4,CHRNB2,SLC24A2,STOML1,CLTC,CNGA3,CNR1,CNTN1,AKAP7,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,COX4I1,CP,SLC32A1,NOS1AP,DBI,HEPH,KLHL3,GRIN3A,DMD,DMPK,DNM2,SLC12A6,DPP6,DRD1,ABCC9,EDN1,EDN3,EDNRA,SGK2,CACNG7,CALCRL,KCNMB2,CACNG3,CACNG2,PTK2B,ATP8A1,SLC9B2,FGF12,FGF14,PRKAG2,FHL1,ATP5PD,ATP13A4,TMEM175,HVCN1,ATP6V1H,ATP2C1,SARAF,OGA,FYN,GABBR1,CAB39,AHCYL1,JPH4,INPP5K,GCK,KCNMB4,GNAO1,GNAS,GPM6A,GPM6B,MCHR1,GPER1,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM7,IL1RAPL1,SLC2A6,HRH3,HTR2A,IGF1,SLC6A17,ITGAV,SLC35G1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NAT8L,MAOB,MT3,MYO5A,NOS1,NPY,NPPA,SLC11A2,HCN1,OPRL1,P2RX7,KCNK10,PDE2A,PDE4B,PDE4D,PIRT,PDPK1,SLC10A4,ABCB1,SERPINE2,NALCN,PIK3C2A,PKD1,TMEM38A,FXYD1,SLC36A4,PPP3CA,NKAIN4,PRKAB2,PRKCB,CNNM2,NKAIN1,SLC6A15,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,SMPD3,ASIC4,SLC30A10,SEC14L1,RASA3,SGK1,SLC6A7,SLC6A8,SLC6A9,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLC22A4,SLN,SNAP25,SNCA,SCN3B,NKAIN2,ABCC8,PLCB1,TPCN2,AZIN2,ATP13A2,TF,SLC44A1,TRPC1,TRPC3,TRPM2,KCNE5,TSC1,SGK3,SLC35A4,BEST1,P2RY12,SLC13A3,KCNK12,KCNT2,ATP6V0E2,SLC30A3,SLC30A4,SLC38A1,SLC17A7,KCNAB1,WNK3,WNK2,SLC17A6,RTN4,TMEM63C,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0021987 cerebral cortex development 3.71E-09 3.64E-05 2.30E-07 2.25E-06 50 121 "ASCL1,NCOA1,BBS2,NRP2,CDK5R1,CDK5R2,CDH2,ADGRG1,SLIT2,LHX2,CNTNAP2,CX3CR1,TRAPPC9,CDON,EGFR,EMX2,FGF13,FGFR1,FOXG1,TACC2,DISC1,GART,FUT10,GRIN1,HNRNPK,AFDN,MDGA1,NEFH,NF1,NPY,NTRK2,PAX6,MBOAT7,POU3F2,RELN,PEX5,FAT4,ROBO1,TRA2B,ARX,BTBD3,SOX2,PLCB1,TACC1,DICER1,NR2E1,TSC1,VLDLR,LRP8,RTN4" GO: Biological Process GO:0051650 establishment of vesicle localization 3.77E-09 3.70E-05 2.32E-07 2.27E-06 85 252 "SYT13,DOC2A,AMPH,CNIH2,SHROOM2,CADPS,ATP2A2,BBS2,SYNJ1,CACNA1A,HAP1,CANX,SYT6,MYRIP,SEC24C,RIMS4,RIMS2,SNPH,RIMS3,DCTN1,CNIH3,BLOC1S6,SEC16A,DNM1,TRAPPC9,DYNC1I1,DNM2,DPYSL2,SYT15,RASGRP1,STX2,F5,F8,SEC24B,FGF14,SYT3,DCTN2,SYT17,CPLX2,CPLX1,PCLO,GRIA1,GRIK5,KIF3A,MYLK2,C2CD4C,SYTL4,SYT9,BLOC1S2,MYO5A,MYO7A,OPHN1,P2RX7,PACSIN1,PRKCZ,SYTL2,RAB3A,LRRK2,STX1B,AP1AR,ITSN1,SH3GL2,NLGN1,SEC31A,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,KIF13A,CLASP2,STX1A,STXBP1,SYT11,SYN1,SYT1,ANKRD28,SYT4,SYT5,CLASP1,GORASP1,WNT7A,TRIM9,AP3B2" GO: Biological Process GO:0048589 developmental growth 4.28E-09 4.20E-05 2.62E-07 2.56E-06 184 673 "SLC25A25,SLITRK1,ADD1,SLC12A5,ADRA1B,ADRB2,NLGN4X,AGT,SEMA6A,ALCAM,UNC79,SEMA7A,PI16,APBA2,EPB41L5,GPAM,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,ADAM15,AZGP1,BBS2,NRP2,CFLAR,BMPR1B,CDK5R1,DDR1,CAMK2D,CAPN3,MAP7,SEPT7,CDC42,DCLK1,LARGE1,NOG,CACNA2D2,SLIT2,LHX2,KMT2C,CPNE6,NIPBL,AKAP6,COL9A1,NCOR1,AATK,CSF1,TENM4,PLXNA4,RIMS2,INTS1,IST1,DBN1,DCC,ZEB2,MAGI2,MED12,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,PLEKHA1,ERBB4,ERCC2,CDKL3,NRN1,FGF1,OLFM1,FGF13,FGFR1,FGFR3,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,CELF1,GAP43,SYT17,DISC1,ATP8A2,MSTN,GDF9,GHR,GLI2,GNAS,GPD2,NR3C1,GSN,MAEL,HNRNPK,IGF1,IGFBP1,NKD1,RBPJ,IL6R,KCNK2,L1CAM,SMAD1,MAPT,MEF2C,CPNE9,MT3,RSPO2,MYH6,NACA,NCAM1,NEK1,NINJ2,NPPA,NRCAM,NTRK3,DDR2,OMG,PDE4D,NLGN3,SEMA5B,PKM,FTO,PLXNB1,RC3H2,POU3F2,MED1,PPP3CB,PRKCZ,PROX1,KLK6,PTCH1,PTHLH,PTK2,PEX5,RBBP6,ROBO1,RXRA,RMI1,SALL1,SEMA6D,DRAXIN,ATXN2,ARX,SLC1A2,SLC12A2,SLIT1,SMARCA4,RIMS1,MBD5,WDTC1,SOX2,SOX10,SOX15,SP2,SPP1,SPART,CLASP2,MESP1,PLCB1,SYT1,COBL,SYT4,SEMA4A,WWC1,TCF7L2,TNS2,SIK3,DICER1,TGFBR3,TIAM1,TLL2,HEY2,TNR,CADM1,UBE3A,FLRT1,WNT7A,NDRG4,RGMA,SEMA3B,PCDH15,RTN4,VANGL2,SLC4A10" GO: Biological Process GO:0051965 positive regulation of synapse assembly 5.47E-09 5.36E-05 3.33E-07 3.25E-06 34 69 "ASIC2,SLITRK1,ADGRB1,ADGRB2,ADGRB3,CBLN1,NRXN3,NRXN1,SLITRK5,EPHB1,STAU2,LRRTM3,LRRTM1,LRRC4B,NTRK2,NTRK3,OXTR,NLGN3,LRRN3,SYNDIG1,LRRTM4,SLITRK3,NLGN1,CLSTN1,CLSTN2,ADGRL3,CUX2,BHLHB9,LRRC24,LRTM2,FLRT2,FLRT1,WNT7A,CBLN2" GO: Biological Process GO:0001764 neuron migration 9.27E-09 9.10E-05 5.62E-07 5.49E-06 60 160 "SEMA6A,MRTFA,APBB1,APBB2,SHTN1,ASCL1,ASTN1,NRP2,CDK5R1,CDK5R2,CCK,DCLK1,ADGRG1,DCC,KIAA0319,DRD1,CELSR3,ERBB4,FKTN,OLFM1,FGF13,FGFR1,FOXG1,NRG3,FYN,CHL1,DISC1,DNER,KIRREL3,GPM6A,HSP90AA1,SCRT2,TUBB2B,MAPT,MARK1,MATN2,MEF2C,MDGA1,NRCAM,NTRK2,NTRK3,PAX6,GPR173,FAT3,MAPK8,RELN,PTK2,PTPRZ1,PEX2,PEX5,FEZF2,ARX,SOX1,ROBO3,UNC5D,CNTN2,ADGRL3,SATB2,FLRT2,FZD3" GO: Biological Process GO:0031345 negative regulation of cell projection organization 1.01E-08 9.90E-05 6.07E-07 5.93E-06 65 179 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,CDK5R1,RAB29,ARHGEF1,CBFA2T2,EVI5L,SLIT2,NRXN1,NGEF,MAP4K4,CRMP1,AATK,ARHGAP24,DCC,KIAA0319,NTM,SEMA3D,SEZ6,CDKL3,EFEMP1,FGF13,SEMA6C,EVL,SEMA4D,GFAP,STMN2,CIT,LINGO1,RBPJ,MAG,MAP4,MBP,MT3,OMG,NLGN3,SEMA5B,PLXNB3,PMP22,FAT3,PPP3CA,PTK2,PTPRG,PTPRO,PTPRZ1,CEP97,RAP1GAP,SEMA6D,DRAXIN,NLGN1,SLIT1,SPP1,RAP1GAP2,SPART,KANK1,SEMA4A,TNR,GORASP1,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0008015 blood circulation 1.16E-08 1.14E-04 6.94E-07 6.78E-06 156 557 "ABAT,ABR,ASIC2,ADCY6,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BBS2,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CBS,CD38,CDC42,CACNA2D2,CHGA,CHRM1,SLIT2,CNR1,AKAP6,CPS1,NOS1AP,DOCK4,HDAC4,DMD,DMPK,DRD1,RCAN1,DNM1L,ABCC9,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,ELN,EPB41,KCNMB2,NCALD,MRVI1,F5,CACNG3,CACNG2,FGF12,GAA,AHCYL1,ERAP1,KCNMB4,GNAO1,GNAS,GPER1,NR3C1,BVES,GUCY1A1,GUCY1B1,HRH3,HMGCR,HSP90AA1,HTR2A,MYLK2,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,KCNMA1,FGFBP3,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NCF2,NOS1,NPY,NPPA,NPR2,OLR1,OPRL1,OXTR,P2RY1,PCSK5,PDE2A,PDE3A,PDE4B,PDE4D,PIK3C2A,PIK3R1,FXYD1,TRHDE,PPARA,PTAFR,PTK2,PTPRO,RAP1GDS1,RPS6KA2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SMPD3,SGK1,SLC2A5,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,TAC3,TACR1,TEK,SIRT1,SPX,TGFBR3,THRA,HEY2,TPM1,TRPC1,KCNE5,AMOT,WNK1,NAV2" GO: Biological Process GO:0021872 forebrain generation of neurons 1.17E-08 1.15E-04 6.94E-07 6.78E-06 36 77 "ASCL1,NUMB,NRP2,NUMBL,SLIT2,CSF1R,DCT,DLX1,DRD1,ERBB4,FGFR1,FOXG1,TBR1,SALL3,DISC1,GBX2,DCLK2,HES5,OGDH,PAX6,POU3F4,PROX1,FEZF2,ROBO1,ROBO2,SALL1,ARX,SLIT1,SMARCC2,SOX1,SOX2,CNTN2,SATB2,DICER1,NR2E1,SLC4A10" GO: Biological Process GO:0051336 regulation of hydrolase activity 1.22E-08 1.20E-04 7.22E-07 7.05E-06 334 1379 "RALGAPA1,SERPINA3,ABR,ACTN2,PLEKHG5,ELFN2,ADCYAP1R1,AXIN2,ADORA2A,ADRB2,AGT,TBC1D14,BCAR3,ARHGAP20,MRTFA,AMPH,BIN1,FGD2,C6orf89,PI16,PKP4,APAF1,ALS2,APOC1,APOC2,APP,SLC7A14,PPP4R4,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ARRB2,ASPH,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,FGF17,BID,CFLAR,ARHGEF7,C5,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAST,BRSK2,ARHGEF25,CCK,RGN,AIFM1,ARHGEF1,DGKI,ARHGEF2,ARHGAP33,EVI5L,CCPG1,RCBTB2,CHM,CHN1,CHN2,CHRM4,ARHGAP22,SLIT2,NGEF,CNN3,ARHGEF6,AKAP6,BAG4,NRG2,CRY2,RGS6,CSF2RA,ARHGEF10,SIPA1L1,VCAN,CST3,RASGEF1C,ARHGEF4,PPP6R2,USP6NL,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,TBC1D5,INTS1,DAPK1,GIT2,DBN1,ELMO1,TIAM2,MAGI2,SPOCK3,SRGAP3,SGSM2,RABGAP1L,DLG2,DLG3,DLG4,DNM2,CPEB2,DOCK2,CASP8AP2,RCAN1,DNAJB6,FIS1,EDNRA,RASGRP1,FAM13A,EGFR,RASA4,EIF5,TNK2,RGS17,PCOLCE2,RASGRP2,EPHA5,ERBB2,ERBB4,DENND4A,F3,TBC1D16,PTK2B,DLC1,RACK1,FGF1,FGFR1,FGFR3,MEX3B,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,ARFGAP2,FYN,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,PCDH11X,PCSK1N,GNAO1,GNAS,ADAP1,GPER1,RAPGEF4,RAPGEF1,RFFL,GRIN1,GRIN2C,GRIN2D,GSN,BVES,FICD,ARHGAP19,NCKAP1L,ARHGAP36,HMGB1,GABARAPL2,HPCA,AGFG1,SMAP1,HTR2A,IFI16,IGF1,DOCK7,KNDC1,INPP5B,ITIH2,JAK1,JAK2,METTL21A,KIT,IPO5,STXBP5,LIMS1,ARHGAP12,SHC3,MEF2C,KITLG,AFDN,GIT1,COL28A1,MT3,MYH6,MYL3,MYO9A,NCAM1,NF1,NODAL,NOS1,SLC11A2,NRDC,NTRK2,NTRK3,TBC1D25,OCRL,OPHN1,PDCD2,PDGFRA,PDPK1,SERPINE2,SERPINI1,A2ML1,NLE1,PLCB2,PLCD1,PLXNB1,PLXNB3,PPP2R2B,PPP2R2C,PTPA,PPP2R5C,PPP2R5E,RASGEF1B,PRKCZ,MAPK7,MAPK8,MAPK9,PSD,BCAS3,SYTL2,PTAFR,PTK2,PXK,PTPRN2,PTX3,RAB3A,RAB3IL1,USP47,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RDX,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,ROBO1,SGSM1,LRRK2,RTKN,MAPK12,SBF1,CSRNP3,FNIP1,ELMOD1,RASA3,ITSN1,ASAP3,DOCK10,PREX2,RAB3GAP1,ARHGEF40,CDK5RAP3,TMEM132D,ARFGAP1,SLN,SNCA,SOX2,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RBM26,RAP1GAP2,SSPO,ST5,MPRIP,RGL1,FGD4,ARHGEF9,DNAJC9,PLCB1,MTCL1,MLST8,MCF2L,DNMBP,TCEA1,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,ATP13A2,SIRT1,TIAM1,TIMP4,RIMBP2,TPM1,TPM2,TRIO,TSC1,TSC2,AMOT,BCL2L13,MTCH1,VAV1,VAV2,MICAL1,TBC1D15,LMF1,P2RY12,WRN,RICTOR,ELFN1,CRB2,WNK1,EVI5,DOCK8,NLRP3,SPATA13" GO: Biological Process GO:0061001 regulation of dendritic spine morphogenesis 1.24E-08 1.21E-04 7.26E-07 7.09E-06 21 33 "CAPRIN2,CDK5R1,KALRN,CAMK2B,NGEF,SIPA1L1,DBN1,BAIAP2,PDLIM5,STAU2,ITPKA,PAK3,NLGN3,RELN,LRRK2,PPP1R9A,NLGN1,CUX2,TIAM1,BHLHB9,LRP8" GO: Biological Process GO:0060560 developmental growth involved in morphogenesis 1.29E-08 1.27E-04 7.54E-07 7.36E-06 81 242 "SEMA6A,ALCAM,SEMA7A,EPB41L5,APP,SHTN1,CPNE5,SEMA4G,NRP2,CDK5R1,DDR1,SEPT7,DCLK1,SLIT2,LHX2,CPNE6,AATK,CSF1,PLXNA4,RIMS2,IST1,DBN1,DCC,ZEB2,MAGI2,MED12,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,NRN1,FGF1,OLFM1,FGF13,SEMA6C,SEMA4D,SYT3,SYT17,DISC1,HNRNPK,NKD1,L1CAM,MAPT,CPNE9,MT3,NRCAM,NTRK3,OMG,NLGN3,SEMA5B,PLXNB1,MED1,PPP3CB,PRKCZ,PTHLH,ROBO1,SALL1,SEMA6D,DRAXIN,SLC12A2,SLIT1,RIMS1,SPP1,SPART,CLASP2,MESP1,SYT1,COBL,SYT4,SEMA4A,TIAM1,TNR,CADM1,FLRT1,RGMA,SEMA3B,RTN4,VANGL2" GO: Biological Process GO:0030048 actin filament-based movement 1.35E-08 1.33E-04 7.86E-07 7.68E-06 50 125 "ACTN2,ANK2,APBB1,APBB2,EPB41L5,SHTN1,ATP1A1,ATP1A2,ATP2A2,CACNA2D1,CACNB2,CAMK2D,MYL6B,AKAP6,MYRIP,NOS1AP,DBN1,DMD,FGF12,EVL,MYLK2,KCNH2,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,PDE4B,PDE4D,FXYD1,MYH14,SCN2B,SCN4B,SCN3B,SYNE2,TMOD1,PARD3,TNNT1,TPM1,TPM2,TPM3,TPM4,KCNE5,WIPF1,WIPF2,FRMD6" GO: Biological Process GO:0044093 positive regulation of molecular function 1.37E-08 1.35E-04 7.91E-07 7.73E-06 440 1893 "RALGAPA1,ABR,ASIC2,ACTN2,PLEKHG5,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADD1,ADD2,AXIN2,ADORA1,ADORA2A,ADRB2,KIDINS220,AGT,TBC1D14,OSBPL8,TAOK1,BCAR3,ARHGAP20,ALK,AMH,AMPH,BIN1,OGT,ANK2,ANK3,FGD2,C6orf89,MAP4K3,PKP4,APAF1,EPB41L5,ALS2,APOC1,APOC2,APP,CDC14B,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,CAPRIN2,ASPH,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,FGF17,BID,CFLAR,CDK5R1,ARHGEF7,BTK,C5,CDK5R2,MMD2,BTRC,CACNA1D,CACNA2D1,CACNB2,DIRAS1,CALM1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,SPAG9,ARHGEF25,CCK,KRIT1,CCNH,CCNT1,RGN,AIFM1,ARHGEF1,SCARB1,SYNGR3,NEURL1,CD81,ARHGEF2,CDC25B,CDC27,CDC42,ARHGAP33,LRRFIP1,EVI5L,RCBTB2,CHM,CHN1,CHN2,CHRM4,TAOK2,ARHGAP22,PLAA,CLU,NGEF,ARHGEF6,AKAP7,AKAP6,AKAP5,MAGED1,NRG2,CLOCK,CSF1,CSF1R,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,CTH,ARHGEF4,USP6NL,NOS1AP,DOCK4,ARHGAP32,GAPVD1,TCAF1,ARHGAP24,HDAC4,RASSF2,TBC1D5,DAPK1,GIT2,ZEB2,ELMO1,B3GAT3,TIAM2,MAGI2,SRGAP3,SGSM2,RABGAP1L,DLG4,DMD,TRAPPC9,DNM2,DOCK2,CASP8AP2,DRD1,ABI1,ARRDC4,DUSP9,DNAJB6,FIS1,EDN1,EDN3,EDNRA,EEF1A2,SGK2,HIPK3,RASGRP1,SH3GLB1,FAM13A,APH1A,EGFR,RASA4,EIF5,TENM1,RGS17,PCOLCE2,EPB41,RASGRP2,EPHA5,ERBB2,ERBB4,ERCC2,DENND4A,F3,TBC1D16,PTK2B,TAOK3,DLC1,RACK1,STRADA,FER,FGF1,FGF13,FGF14,FGFR1,FGFR3,FGR,PRKAG2,MEX3B,CAP2,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,ARFGAP2,CAMKK2,NRG3,FYN,GAB1,CAB39,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,DBF4,GNAL,GNAO1,GNAS,GNG3,PSRC1,ADAP1,GPER1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GSN,MAP4K5,IRAK3,ARHGAP19,NCKAP1L,TNFAIP8L3,ARHGAP36,HMGB1,GABARAPL2,HPCA,AGFG1,SMAP1,HTR2A,IFI16,IGF1,DOCK7,KNDC1,IL6R,INPP5B,JAK1,JAK2,KCNJ11,KIT,STXBP5,LIMS1,ARHGAP12,MDFI,SHC3,MEF2C,MIA2,KITLG,AFDN,MMP16,MMP17,GIT1,DBNL,MT3,MYL3,MYO9A,NCAM1,NDP,NELL1,NEUROD1,NEUROD2,NF1,NKX2-2,NODAL,NOS1,NPPA,SLC11A2,HCN1,NTRK3,DDR2,TBC1D25,OCRL,OPHN1,P2RX7,PAK3,PDCD2,PIRT,PDGFRA,PDPK1,CYTL1,PFKFB2,NLGN3,PKD1,PLCB2,PLCL1,PLXNB1,MED1,PTPA,PPP3CA,RASGEF1B,PRKACB,PRKAR1B,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PSD,BCAS3,PSMA6,PSMD13,PTAFR,PTK2,PPP2R3C,RAB3A,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,DCUN1D2,ROBO1,FBXW7,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,ELMOD1,RASA3,SGK1,ITSN1,PPP1R9A,ASAP3,DOCK10,MAGI3,AMBRA1,PREX2,KDM4D,RAB3GAP1,ARHGEF40,SIRT2,CCDC88A,SLC11A1,ARFGAP1,SMARCA4,MAPKBP1,SNCA,USP33,TNIK,FNBP1,ERC1,BEX1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,TAB2,STOX1,ST5,MAPK8IP3,RGL1,FGD4,ARHGEF9,DNAJC9,PLCB1,ARC,MTCL1,MCF2L,DNMBP,TCEA1,TCF7L2,AZIN2,DOCK9,PSD3,ARHGEF12,ARHGAP9,CRTC1,TEK,TF,SIRT1,TGFBR3,AKTIP,TIAM1,TLR4,ZFP91,PIK3R5,TP53BP1,TPM1,TRIO,TSC1,TSC2,SGK3,UBC,BCL2L13,MTCH1,VAV1,VAV2,VIPR2,VLDLR,TBC1D15,LMF1,P2RY12,WRN,RICTOR,XRCC4,ZIC2,WNK1,MAP3K12,LRP8,EVI5,WNK3,WNK2,DOCK8,NLRP3,VANGL2,SPATA13" GO: Biological Process GO:0048709 oligodendrocyte differentiation 1.44E-08 1.42E-04 8.27E-07 8.08E-06 41 94 "ASCL1,ASPA,MYRF,CLU,QKI,TENM4,DLX1,OLIG1,MED12,OLIG2,ERBB2,ERCC2,PRMT5,FGFR3,NKX6-2,WASF3,GSN,LINGO1,HES5,KCNJ10,NF1,NKX2-2,NTRK2,OMG,PAX6,ENPP2,NLGN3,PLP1,FA2H,PTPRZ1,SOX8,SOX6,SLC8A3,SIRT2,SOX5,SOX10,SOX11,CNTN2,TCF7L2,DICER1,PRDM8" GO: Biological Process GO:0007163 establishment or maintenance of cell polarity 1.67E-08 1.63E-04 9.50E-07 9.28E-06 65 181 "ANK1,APC,SHTN1,DST,BRSK2,MAP7,KRIT1,ARHGEF2,CDC42,LHX2,CDC42BPB,SNAP91,PARD6A,DLG2,DLG3,DLG4,DOCK2,WDPCP,EPHB1,EYA1,PTK2B,RACK1,FGF13,CAP2,BRSK1,NCKAP1,GSN,KIF3A,NCKAP1L,IGF1,DOCK7,HES5,LIMS1,MAP2,MAP4,NUMA1,PAX6,PKD1,GPSM2,PRKCZ,BCAS3,LAMA1,PTK2,SPDL1,FERMT1,MYO18A,CDK5RAP2,CLASP2,ERBIN,KANK1,SYNE2,MTCL1,WWC1,RPGRIP1L,CLASP1,TEK,CRB1,HEY1,PARD3,AMOT,WNT7A,RICTOR,CRB2,SNX27,VANGL2" GO: Biological Process GO:0003013 circulatory system process 1.72E-08 1.69E-04 9.75E-07 9.52E-06 156 560 "ABAT,ABR,ASIC2,ADCY6,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ANK2,SPTBN4,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BBS2,HCN2,CACNA1G,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CBS,CD38,CDC42,CACNA2D2,CHGA,CHRM1,SLIT2,CNR1,AKAP6,CPS1,NOS1AP,DOCK4,HDAC4,DMD,DMPK,DRD1,RCAN1,DNM1L,ABCC9,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,ELN,EPB41,KCNMB2,NCALD,MRVI1,F5,CACNG3,CACNG2,FGF12,GAA,AHCYL1,ERAP1,KCNMB4,GNAO1,GNAS,GPER1,NR3C1,BVES,GUCY1A1,GUCY1B1,HRH3,HMGCR,HSP90AA1,HTR2A,MYLK2,JAK2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK3,KCNMA1,FGFBP3,MDM4,CTNNA3,MYH6,MYH7,MYL3,FXYD7,FXYD6,NCF2,NOS1,NPY,NPPA,NPR2,OLR1,OPRL1,OXTR,P2RY1,PCSK5,PDE2A,PDE3A,PDE4B,PDE4D,PIK3C2A,PIK3R1,FXYD1,TRHDE,PPARA,PTAFR,PTK2,PTPRO,RAP1GDS1,RPS6KA2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2B,SCN4B,SMPD3,SGK1,SLC2A5,SLC8A2,SLC8A1,SLC8A3,SCN3B,SP4,TAC1,TAC3,TACR1,TEK,SIRT1,SPX,TGFBR3,THRA,HEY2,TPM1,TRPC1,KCNE5,AMOT,WNK1,NAV2" GO: Biological Process GO:0030036 actin cytoskeleton organization 1.74E-08 1.70E-04 9.79E-07 9.56E-06 163 591 "ABR,ACTN1,ACTN2,FMNL2,ADD1,ADD2,ERMN,MRTFA,CDC42BPA,FGD2,PPFIA1,EPB41L5,GAS7,SHTN1,SHROOM2,SPTBN4,ARHGDIA,ARRB1,DYNLL1,CFLAR,CDK5R1,WASF1,LURAP1,CAPN3,BRSK2,FMNL3,ARHGEF2,CDC42,CFL2,TAOK2,SLIT2,CNN3,PICK1,BAG4,CDC42BPB,CSF1R,ARHGEF10,MICAL2,SIPA1L1,MYADM,DAPK3,SIRPA,DBN1,ELMO1,SHANK1,DOCK2,ABI1,DNAJB6,USH1C,EDN1,FRY,ABI2,SORBS3,TENM1,EPB41,EPB41L1,EPB41L2,DMTN,EPHA5,EPS8,PTK2B,CORO2B,DLC1,TESK2,FER,BAIAP2,MAD2L2,FGR,AGAP2,EVL,SORBS1,ATP2C1,STAU2,ABLIM2,NCKAP1,IQGAP2,INPP5K,WASF3,ARFIP1,RND1,GPM6B,CIT,GSN,PACSIN2,NCKAP1L,SYNPO,SMAP1,SCIN,ITPKA,JAK2,KIT,MEF2C,MKLN1,DBNL,MYH3,MYH6,NF1,NTRK3,OPHN1,PAK3,PDGFRA,PDPK1,TMOD2,SSH1,PIK3R1,MAGEL2,EPB41L4B,PACSIN1,PRKCZ,PROX1,BCAS3,GDPD2,IQSEC3,RAP1GDS1,RDX,MYH14,KIRREL1,AP1AR,MRAS,PPP1R9A,PPM1E,ASAP3,MYO18A,FHOD3,ABLIM3,CCDC88A,TTC17,LIMCH1,PALLD,TNIK,ARHGAP26,SPTAN1,SPTB,IQSEC2,CLASP2,EPB41L3,KANK1,FGD4,COBL,TAC1,TACR1,MLST8,CLASP1,OBSL1,FRYL,TEK,TF,TMOD1,DAAM2,TPM1,TSC1,TMEFF2,AMOT,PLEKHH2,MICAL1,WIPF1,RICTOR,FMN2,SPIRE1,PCDH15,WIPF2,ACTR3B,VANGL2" GO: Biological Process GO:0017156 calcium ion regulated exocytosis 1.75E-08 1.72E-04 9.81E-07 9.58E-06 52 133 "SYT13,DOC2A,CADPS,ATP2A2,SYNJ1,CACNA1I,CACNA1G,CDK5R2,CACNA1A,SYT6,CBARP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SYT15,STX2,SYT3,SYT17,CPLX2,CPLX1,PCLO,RAPGEF4,GRIK5,SCIN,C2CD4C,KCNB1,SYTL4,SYT9,SCAMP5,P2RX7,PPP3CB,SYTL2,RAB3A,LRRK2,STX1B,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,TRIM9" GO: Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential 1.93E-08 1.89E-04 1.07E-06 1.05E-05 18 26 "NRXN1,RIMS2,DBN1,DLG4,SHANK1,PTK2B,GRIN1,NLGN3,PRKCZ,RELN,STX1B,NLGN1,RIMS1,STX1A,CUX2,WNT7A,NETO2,NETO1" GO: Biological Process GO:0014013 regulation of gliogenesis 1.93E-08 1.90E-04 1.07E-06 1.05E-05 46 112 "BIN1,ASPA,SYNJ1,CDH2,NOG,GPR37L1,QKI,CSF1,TENM4,DLX1,OLIG2,EFEMP1,PRMT5,FGFR3,DLL3,NKX6-2,GFAP,LINGO1,HES5,IL6ST,MAG,MBD1,AFDN,MYCN,NF1,NKX2-2,NTRK3,ENPP2,SERPINE2,PTK2,PTN,PTPRZ1,SOX8,ATXN1,SIRT2,ZCCHC24,SOX10,SOX11,CNTN2,TCF7L2,TF,DICER1,TIAM1,NR2E1,P2RY12,RTN4" GO: Biological Process GO:0010977 negative regulation of neuron projection development 2.16E-08 2.12E-04 1.19E-06 1.16E-05 57 152 "ADCY6,SEMA6A,SEMA7A,SEMA4G,ARHGDIA,CDK5R1,RAB29,ARHGEF1,CBFA2T2,SLIT2,NGEF,MAP4K4,CRMP1,AATK,DCC,KIAA0319,NTM,SEMA3D,SEZ6,CDKL3,EFEMP1,FGF13,SEMA6C,SEMA4D,GFAP,STMN2,CIT,LINGO1,RBPJ,MAG,MBP,MT3,OMG,NLGN3,SEMA5B,PMP22,FAT3,PPP3CA,PTK2,PTPRG,PTPRO,PTPRZ1,SEMA6D,DRAXIN,NLGN1,SLIT1,SPP1,RAP1GAP2,SPART,KANK1,SEMA4A,TNR,GORASP1,RGMA,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0006835 dicarboxylic acid transport 2.22E-08 2.18E-04 1.22E-06 1.19E-05 43 102 "ABAT,ADORA1,ADORA2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,ATP1A2,CCK,SLC22A6,DPYSL2,FOLR2,GABBR1,CPLX1,GLS,NR3C1,GRM2,GRM7,HRH3,KCNJ10,MYO6,NF1,NTRK2,P2RX7,SLC26A11,RAB3A,SLC1A2,SLC1A3,SLC1A6,SLC1A7,RAB3GAP1,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,SLC19A3,TRH,SLC13A3,SLC26A10,SLC17A7,SLC17A6" GO: Biological Process GO:0051050 positive regulation of transport 2.54E-08 2.49E-04 1.39E-06 1.35E-05 265 1061 "ABAT,ABR,ASIC2,ACHE,ACTN2,ADCYAP1R1,ADD1,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,OSBPL8,PLA2G6,C1QTNF1,C1QTNF3,BIN1,ANK2,ANK3,APBB1,CASK,ARRB1,ARRB2,CADPS,ASPH,DYNLL1,ATP1B3,ATP2B2,BID,CDK5R1,SYNJ1,ARHGEF7,MTMR2,CACNA1I,CACNA1G,C5,RAB29,CDK5R2,IL33,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CALM1,HAP1,CAMK2A,CAPN3,CCK,CCKBR,RGN,SYNGR3,CD38,CDC42,CDH2,CHRM1,CHRNA4,CHRNB2,PICK1,CNTN1,AKAP7,AKAP6,AKAP5,MYRIP,CLIP3,ABCG1,CSF1R,CALY,NOS1AP,TCAF1,TBC1D5,DBI,SIRPA,B3GAT3,C2CD2L,MAGI2,DMD,DNM1,DNM2,DOCK2,DPP6,DPYSL2,DRD1,PDCD6IP,DNM1L,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,RASGRP1,SH3GLB1,EGFR,TENM1,ERBB2,ERBB4,TLR7,SIRPB1,ATP8A1,RACK1,FCGR1A,FGF12,FGF14,FGFR1,FGR,FHL1,MEX3B,ANKFY1,SGIP1,SYT3,SORBS1,ZBED3,TRIM16,PRELID3A,OGA,GABBR1,AHCYL1,GALR1,ATP8A2,INPP5K,GCK,GLUL,GNAS,MCHR1,GPR26,GPER1,RAPGEF4,GRIK1,NR3C1,KIF3A,PTPN5,NCKAP1L,HMGB1,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,IGF1,SCIN,ITGAV,JAK2,KCNB1,KCNC1,KCNC2,KCNH2,KCNJ11,KCNN3,IPO5,STXBP5,SYTL4,NAT8L,SYT9,SCAMP5,MYBPC1,HNRNPM,NELL2,NFE2L2,NNAT,NODAL,NOS1,NPPA,CLEC9A,HCN1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PIRT,PDPK1,PFKFB2,ZDHHC8,NLGN3,PIK3R1,PLCD1,FXYD1,PLTP,MED1,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PRKCZ,MAPK8,MAPK9,RELN,BCAS3,SYTL2,PTAFR,PTCH1,PTK2,PTX3,RAB3A,RAP1GAP,RDX,RNASEL,FBXW7,WLS,STX1B,SCN4B,SCP2,SMPD3,ELMOD1,IL17RB,SGK1,MYO18A,NLGN1,ABLIM3,SLC1A2,SLC6A1,RAB3GAP1,SLC11A1,RIMS1,SNAP25,SNCA,SCN3B,SOX11,CLASP2,STX1A,KANK1,SULF2,STXBP1,MLC1,ABCC8,PLCB1,ARC,SYT1,TAC1,TACR1,MTCL1,ACSL6,TCF7L2,CLASP1,AZIN2,SYNE1,TEK,ATP13A2,TF,SIRT1,TLR4,PARD3,TP53BP2,ZNF384,TRH,TRPC1,TRPC3,TRPM2,KCNE5,TUB,SGK3,CADM1,VSNL1,WIPF1,P2RY12,ZIC1,SLC30A3,WNK1,MFF,HPS4,WNK3,WNK2,RTN4,NLRP3" GO: Biological Process GO:0099601 regulation of neurotransmitter receptor activity 2.67E-08 2.62E-04 1.45E-06 1.41E-05 21 34 "CNIH2,CHRNA4,NRXN1,CRHBP,DAPK1,CNIH3,DLG4,SHANK1,CACNG7,CACNG3,CACNG2,PTK2B,PPARGC1A,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1,ARC,NETO2" GO: Biological Process GO:0051968 "positive regulation of synaptic transmission, glutamatergic" 2.83E-08 2.77E-04 1.52E-06 1.48E-05 17 24 "ADORA2A,CCKBR,NRXN1,DRD1,EGFR,PTK2B,GLUL,GRIA4,NTRK2,OXTR,NLGN3,RELN,NLGN1,RAB3GAP1,SHANK2,IQSEC2,TNR" GO: Biological Process GO:0048588 developmental cell growth 2.83E-08 2.78E-04 1.52E-06 1.48E-05 75 222 "AGT,SEMA6A,ALCAM,SEMA7A,PI16,APP,SHTN1,CPNE5,SEMA4G,NRP2,CDK5R1,DDR1,CAMK2D,SEPT7,DCLK1,SLIT2,LHX2,CPNE6,AKAP6,AATK,PLXNA4,RIMS2,IST1,DBN1,DCC,ZEB2,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,NRN1,OLFM1,FGF13,SEMA6C,SEMA4D,SYT3,PDLIM5,SYT17,DISC1,GDF9,NR3C1,HNRNPK,L1CAM,MAPT,CPNE9,MT3,NPPA,NRCAM,NTRK3,OMG,NLGN3,SEMA5B,PLXNB1,PPP3CB,PRKCZ,SEMA6D,DRAXIN,SLIT1,RIMS1,SPP1,SPART,CLASP2,SYT1,COBL,SYT4,SEMA4A,TIAM1,TNR,FLRT1,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0043085 positive regulation of catalytic activity 3.08E-08 3.02E-04 1.64E-06 1.60E-05 375 1588 "RALGAPA1,ABR,ACTN2,PLEKHG5,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRB2,KIDINS220,AGT,TBC1D14,OSBPL8,TAOK1,BCAR3,ARHGAP20,ALK,AMPH,BIN1,OGT,FGD2,C6orf89,MAP4K3,PKP4,APAF1,ALS2,APOC1,APOC2,APP,CDC14B,MADD,SPTBN4,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,RGS20,ASPH,ATP1B3,RIPK1,DOCK11,ADGRB3,RGS11,RGS9,FGF17,BID,CFLAR,CDK5R1,ARHGEF7,C5,CDK5R2,MMD2,BTRC,DIRAS1,CALM1,KALRN,NGB,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SPAG9,ARHGEF25,CCK,CCNH,CCNT1,RGN,AIFM1,ARHGEF1,SCARB1,NEURL1,CD81,ARHGEF2,CDC25B,CDC27,CDC42,ARHGAP33,EVI5L,RCBTB2,CHM,CHN1,CHN2,CHRM4,TAOK2,ARHGAP22,PLAA,CLU,NGEF,ARHGEF6,AKAP6,AKAP5,MAGED1,NRG2,CSF1,CSF1R,RGS6,CSF2RA,ARHGEF10,SIPA1L1,RASGEF1C,ARHGEF4,USP6NL,NOS1AP,DOCK4,ARHGAP32,GAPVD1,ARHGAP24,RASSF2,TBC1D5,DAPK1,GIT2,ZEB2,ELMO1,B3GAT3,TIAM2,MAGI2,SRGAP3,SGSM2,RABGAP1L,DLG4,DNM2,DOCK2,CASP8AP2,DRD1,ABI1,ARRDC4,DUSP9,DNAJB6,FIS1,EDN1,EDN3,EDNRA,EEF1A2,RASGRP1,SH3GLB1,FAM13A,APH1A,EGFR,RASA4,EIF5,TENM1,RGS17,PCOLCE2,RASGRP2,ERBB2,ERBB4,DENND4A,F3,TBC1D16,PTK2B,TAOK3,DLC1,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,FGR,PRKAG2,MEX3B,CAP2,AGAP2,AGAP3,SEMA4D,FLT1,PSD2,APOPT1,ARFGAP2,CAMKK2,NRG3,FYN,GAB1,CAB39,DENND2A,RAPGEF6,IQGAP2,GFRA1,GFRA2,GHR,MALT1,RUNDC3A,COPS8,DBF4,GNAL,GNAO1,GNAS,GNG3,PSRC1,ADAP1,GPER1,RAPGEF4,RAPGEF1,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GSN,MAP4K5,ARHGAP19,NCKAP1L,TNFAIP8L3,ARHGAP36,HMGB1,GABARAPL2,HPCA,AGFG1,SMAP1,HTR2A,IFI16,IGF1,DOCK7,KNDC1,IL6R,INPP5B,JAK1,JAK2,KIT,STXBP5,LIMS1,ARHGAP12,MDFI,SHC3,MEF2C,MIA2,KITLG,AFDN,MMP16,MMP17,GIT1,DBNL,MT3,MYL3,MYO9A,NCAM1,NELL1,NF1,NODAL,NOS1,SLC11A2,NTRK3,DDR2,TBC1D25,OCRL,OPHN1,P2RX7,PAK3,PDCD2,PDGFRA,PDPK1,PFKFB2,PKD1,PLCB2,PLXNB1,PTPA,RASGEF1B,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PSD,BCAS3,PSMA6,PSMD13,PTAFR,PTK2,PPP2R3C,RAB3A,RAB3IL1,RALGDS,IQSEC3,RAP1GAP,RAP1GDS1,RASGRF1,RASGRF2,RET,RGS3,RGS4,RGS7,RGS10,RGS12,ARHGEF10L,RIC8B,DCUN1D2,ROBO1,FBXW7,SGSM1,LRRK2,MAPK12,SBF1,FNIP1,ELMOD1,RASA3,ITSN1,PPP1R9A,ASAP3,DOCK10,MAGI3,AMBRA1,PREX2,RAB3GAP1,ARHGEF40,CCDC88A,SLC11A1,ARFGAP1,MAPKBP1,SNCA,TNIK,FNBP1,ARHGAP26,SPTAN1,SPTB,IQSEC2,MCF2L2,RAP1GAP2,TAB2,STOX1,ST5,MAPK8IP3,RGL1,FGD4,ARHGEF9,DNAJC9,PLCB1,MTCL1,MCF2L,DNMBP,TCEA1,AZIN2,DOCK9,PSD3,ARHGEF12,ARHGAP9,TEK,TF,SIRT1,TIAM1,TLR4,ZFP91,PIK3R5,TPM1,TRIO,TSC1,TSC2,UBC,BCL2L13,MTCH1,VAV1,VAV2,VIPR2,VLDLR,TBC1D15,LMF1,P2RY12,WRN,RICTOR,XRCC4,MAP3K12,LRP8,EVI5,DOCK8,NLRP3,VANGL2,SPATA13" GO: Biological Process GO:0019226 transmission of nerve impulse 4.05E-08 3.97E-04 2.15E-06 2.10E-05 36 80 "AGT,ANK3,CNTNAP1,PRX,SPTBN4,CACNA1I,CACNA1A,CACNA1E,CACNB4,CNTNAP2,DPP6,DRD1,CACNG7,KCNMB2,CACNG3,CACNG2,KCNMB4,GPER1,RAPGEF4,GRIA1,GRIK2,GRM7,KCNA1,KCNA2,KCND2,KCNMA1,KCNQ2,NRCAM,GPR88,MYH14,SCN2A,SCN3A,SCN7A,SCN8A,NFASC,TNR" GO: Biological Process GO:0044089 positive regulation of cellular component biogenesis 4.17E-08 4.09E-04 2.20E-06 2.15E-05 130 453 "ASIC2,SLITRK1,AGT,KIAA1324,APC,EPB41L5,ATM,ADGRB1,ADGRB2,ADGRB3,BID,BMP7,WASF1,HAP1,CBLN1,CCK,LDB2,NEURL1,SEPT7,CDC42,CDH2,CHGA,NRXN3,NRXN1,CLU,PICK1,BAG4,CHD1L,GDA,ARHGEF10,SLITRK5,HDAC4,MAGI2,DNM2,PDCD6IP,EDN1,SH3GLB1,ABI2,SORBS3,TENM1,PAN3,EPHB1,ERCC2,PTK2B,RACK1,FER,BAIAP2,EVL,STAU2,NCKAP1,IQGAP2,SEPT9,ARFIP1,PSRC1,GPM6A,TPPP,GSN,NCKAP1L,SYNPO,HSP90AA1,IRF8,SCIN,LRRTM3,LRRTM1,KIT,LRRC4B,LIMS1,MAPT,MITF,NTRK2,NTRK3,OXTR,P2RX7,PALM,ENPP2,NLGN3,MAGEL2,LRRN3,MAPK8,MAPK9,PROX1,BCAS3,KCTD17,KIRREL1,SYNDIG1,ATAT1,CLIP1,AP1AR,LRRTM4,FNIP1,PPM1E,FUZ,SLITRK3,NLGN1,CLSTN1,RAB3GAP1,RIMS1,PALLD,CLASP2,CLSTN2,TTBK2,PHLDB1,COBL,TAC1,TACR1,MLST8,TAL1,ADGRL3,CUX2,CLASP1,TEK,BHLHB9,TLR4,TPM1,LRRC24,ZMYND8,TSC1,LRTM2,AMOT,FLRT2,FLRT1,WIPF1,WNT7A,RICTOR,FMN2,SPIRE1,PLPPR5,WIPF2,ACTR3B,CBLN2" GO: Biological Process GO:1900449 regulation of glutamate receptor signaling pathway 4.32E-08 4.23E-04 2.26E-06 2.21E-05 20 32 "CNIH2,NRXN1,CRHBP,DAPK1,CNIH3,DLG4,SHANK1,CACNG7,CACNG3,CACNG2,PTK2B,PPARGC1A,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1,ARC,NETO2" GO: Biological Process GO:0060999 positive regulation of dendritic spine development 4.39E-08 4.31E-04 2.29E-06 2.24E-05 24 43 "CAPRIN2,KALRN,CAMK2B,NEURL1,DBN1,SHANK1,EIF4G2,BAIAP2,STAU2,NR3C1,HNRNPK,ITPKA,PAK3,PALM,NLGN3,RELN,PPP1R9A,CPEB3,NLGN1,CUX2,TIAM1,BHLHB9,ZMYND8,LRP8" GO: Biological Process GO:0061351 neural precursor cell proliferation 4.46E-08 4.37E-04 2.31E-06 2.26E-05 60 166 "FZD9,DISP3,ASCL1,NUMB,PTBP2,CDH2,NOG,NUMBL,GPR37L1,ADGRG1,NCOR2,CX3CR1,DBN1,DCT,ZEB2,CDON,EML1,EMX2,EPHB1,CEND1,FABP7,FGF13,FGFR1,FOXG1,FOXO3,TACC2,DISC1,GBX2,GLI2,KDM2B,RAPGEF1,KIF3A,IGF1,DOCK7,INSM1,KCNA1,LIMS1,AFDN,NF1,PAX6,POU3F2,PROX1,PTPRZ1,LRRK2,SALL1,ARX,LIMS2,SIRT2,SMARCD3,SOX2,SOX5,SOX10,TACC1,ACSL6,TF,HHIP,NR2E1,WNT7A,FZD3,IFT88" GO: Biological Process GO:0046717 acid secretion 5.46E-08 5.35E-04 2.82E-06 2.75E-05 49 126 "ABAT,ADORA1,ADORA2A,PLA2G6,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CACNA1A,CACNB4,CCK,CCKBR,PNPLA8,DPYSL2,EDN1,ACSL4,GABBR1,STARD10,CPLX1,GLS,GRIK1,NR3C1,GRM2,GRM7,HRH3,MYO6,NF1,NTRK2,OPRL1,OXTR,P2RX7,MAPK9,RAB3A,SGK1,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A9,RAB3GAP1,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,TRH,SLC17A7" GO: Biological Process GO:0021879 forebrain neuron differentiation 6.18E-08 6.07E-04 3.18E-06 3.10E-05 32 68 "ASCL1,NRP2,SLIT2,CSF1R,DLX1,DRD1,ERBB4,FGFR1,FOXG1,TBR1,SALL3,DISC1,GBX2,DCLK2,HES5,OGDH,PAX6,POU3F4,PROX1,FEZF2,ROBO1,ROBO2,SALL1,ARX,SLIT1,SMARCC2,SOX1,SOX2,CNTN2,SATB2,DICER1,SLC4A10" GO: Biological Process GO:0060998 regulation of dendritic spine development 6.73E-08 6.60E-04 3.44E-06 3.36E-05 31 65 "CAPRIN2,CDK5R1,KALRN,CAMK2B,NEURL1,NGEF,SIPA1L1,DBN1,SHANK1,EIF4G2,BAIAP2,PDLIM5,STAU2,DISC1,NR3C1,HNRNPK,ITPKA,MEF2C,PAK3,PALM,NLGN3,RELN,LRRK2,PPP1R9A,CPEB3,NLGN1,CUX2,TIAM1,BHLHB9,ZMYND8,LRP8" GO: Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis 7.08E-08 6.95E-04 3.60E-06 3.52E-05 40 95 "SYT13,DOC2A,CADPS,ATP2A2,CACNA1I,CACNA1G,CDK5R2,CACNA1A,SYT6,CBARP,RIMS4,RIMS2,RIMS3,SYT15,SYT3,SYT17,GRIK5,C2CD4C,KCNB1,SYTL4,SYT9,SCAMP5,SYTL2,RAB3A,LRRK2,STX1B,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,TRIM9" GO: Biological Process GO:0006468 protein phosphorylation 7.20E-08 7.06E-04 3.64E-06 3.55E-05 447 1952 "KCNH8,CLK4,ACTN2,NDRG2,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,BRAP,CDC7,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,BCAR3,ALK,OGT,CDC42BPA,SEMA7A,FGD2,MAP4K3,APC,ALS2,LRRC4C,APP,CDK10,MADD,CASK,SPTBN4,ZFYVE28,ARRB1,ARRB2,CDK13,STK33,MARK4,CAPRIN2,ATM,EIF4G3,RIPK1,FGF17,BLM,KSR1,BMP7,BMPR1B,CDK5R1,BTK,C5,CDK5R2,LDLRAD4,MMD2,BTRC,DDR1,DIRAS1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,SPAG9,CBS,CCK,CCKBR,CCNH,CCNT1,RGN,NEURL1,CD81,CDK11B,ARHGEF2,CDC25B,CDC42,CDH2,DCLK1,TBRG4,NOG,CRLF1,GPR37L1,SOCS6,TAOK2,SLIT2,CLU,FBXO7,MAP4K4,ARHGEF6,PICK1,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,NRG2,CDC42BPB,NCOR1,CLIP3,AATK,CSF1,CSF1R,CSF2RA,CSNK1E,CSNK1G3,SOCS5,CTNND1,MYADM,FGFR1OP2,RASSF2,MAML1,DAPK1,DAPK3,DCC,ZEB2,PARD6A,DLG4,DMD,DMPK,RPS6KL1,CDON,DRD1,ABI1,DUSP9,DYRK1A,EDN1,EDN3,EDNRA,EDNRB,SGK2,HIPK3,RASGRP1,CELSR3,EGFR,ABI2,RASA4,SORBS3,IRAK4,TENM1,TNK2,SRPK3,PAN3,DMTN,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,SPEG,CDKL3,DNAJC27,TLR7,RPS6KC1,PTK2B,TAOK3,EFEMP1,RACK1,FKTN,STRADA,PRMT5,TESK2,PPP1R1B,FECH,FER,FGF1,FGF12,FGF13,FGF14,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,MEX3B,AGAP2,FOXM1,SEMA4D,FLT1,WDR83,ZBED3,NPTN,CAMKK2,NRG3,BRSK1,FYB1,FYN,GAB1,CAB39,ZMYND11,ZNF274,NEK6,IP6K3,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA1,GFRA2,GHR,PPARGC1A,MALT1,TTBK1,COPS8,DCLK2,GNAS,GNG3,PSRC1,GPER1,GPR37,GRK4,CNTRL,RAPGEF1,C1QL4,GRIK2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,CIT,PTPN5,MAP4K5,IRAK3,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HSP90AA1,HTR2A,MYLK2,IGF1,NIM1K,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,INSM1,LRRTM3,LRRTM1,ITGAV,ITPKA,ITPKB,JAK1,JAK2,KCNH1,KCNH2,KIT,LRRC4B,CAMK2N2,FGFBP3,SMAD1,SMAD9,PIK3AP1,MARK1,MARK3,MATK,MDFI,SHC3,MEF2C,KITLG,MID1,PPM1L,DBNL,STK32C,NRBP2,MT3,NCAM1,NELL1,NEK1,NF1,NODAL,NOS1,NPR2,NTRK2,NTRK3,DDR2,KSR2,OPRL1,OXTR,P2RX7,P2RY1,TREM2,PAK3,PAX6,CDK18,PDE4D,PDGFRA,ENPP2,PDPK1,CDK14,DUSP26,PHKG1,CAMKV,PIK3CD,PIK3R1,PKD1,PLCL1,MED1,PPP1R1A,LRRN3,PPP3CB,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PSMA6,LAMA1,SNRK,PSMD13,PTK2,PXK,STK32A,PTPRZ1,PPP2R3C,PID1,RASGRF1,RASGRF2,DUSP15,RET,RGS3,RGS4,RNASEL,KIRREL1,NEK11,EPHA10,FBXW7,PRR5L,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,LRRTM4,FNIP1,TNFRSF19,RASA3,SGK1,PPP1R9A,PPM1E,MAGI3,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,MAST1,MAPKBP1,SNCA,LMBRD1,SOX2,TNIK,DOK5,ERC1,DBNDD2,SPTAN1,SPTB,CDK19,TSPYL2,LMO3,SRPK2,TAB2,PBLD,STOX1,SAMSN1,LRRC4,ST5,MAPK8IP3,MPRIP,NEK4,TTBK2,FGD4,PLCB1,MLST8,WWC1,FBXW11,NSD1,SIK3,TEK,ATP13A2,TF,DICER1,SIRT1,LEFTY2,TGFBR3,AKTIP,THBS4,TIAM1,TIE1,TLR4,ZFP91,TNFRSF1B,PARD3,PIK3R5,CDK20,IL34,NR2C2,TRIO,NTSR2,TSC1,TSC2,SGK3,UBC,UCHL1,FLRT2,FLRT1,MICAL1,VLDLR,WNT7A,RICTOR,NDRG4,WNK1,PMEPA1,MAP3K12,LRP8,RGMA,SCG2,WNK3,WNK2,NELFE,PAK5,CAMK1G,VANGL2,SOCS4" GO: Biological Process GO:0021954 central nervous system neuron development 7.68E-08 7.54E-04 3.86E-06 3.78E-05 37 85 "SPTBN4,ASCL1,NRP2,DCLK1,CHRNB2,SLIT2,PLXNA4,DCC,ZEB2,DRD1,EPHB1,FGFR1,FOXG1,GABRB1,SALL3,DISC1,GBX2,GLI2,DCLK2,LINGO1,MAP2,NPY,NTRK2,OGDH,PTK2,FEZF2,ROBO1,ROBO2,ARX,SLIT1,SOX1,MYCBP2,CNTN2,SZT2,NR2E1,PRDM8,SLC4A10" GO: Biological Process GO:0008306 associative learning 8.25E-08 8.10E-04 4.13E-06 4.04E-05 39 92 "ASIC1,ADRA1B,ADRB2,APBB1,APP,PDE8B,ATP1A2,ATP1A3,CACNA1E,NOG,CHRNB2,SHANK1,DRD1,PPP1R1B,NPTN,TBR1,GABRA5,GRIN1,GRM7,HMGCR,KIT,MEIS2,NEUROD2,NF1,NPTX2,NRGN,PDE1B,NLGN3,RELN,PTPRZ1,ATXN1,SGK1,SNAP25,TAC1,TACR1,DDHD2,TNR,NDRG4,NETO1" GO: Biological Process GO:0007158 neuron cell-cell adhesion 8.72E-08 8.55E-04 4.32E-06 4.22E-05 13 16 "NLGN4X,ASTN1,CDK5R1,NRXN3,NRXN1,NRXN2,NCAM2,NINJ2,NLGN3,RET,NLGN4Y,NLGN1,TNR" GO: Biological Process GO:2000310 regulation of NMDA receptor activity 8.72E-08 8.55E-04 4.32E-06 4.22E-05 13 16 "CNIH2,NRXN1,CRHBP,DAPK1,DLG4,PTK2B,PPARGC1A,MEF2C,NLGN3,RELN,RASGRF1,RASGRF2,NLGN1" GO: Biological Process GO:0046578 regulation of Ras protein signal transduction 9.34E-08 9.16E-04 4.60E-06 4.50E-05 68 200 "ABR,PLEKHG5,ADRA1B,OGT,FGD2,DGKZ,ALS2,MADD,ARHGDIA,ARRB1,ARHGEF7,MMD2,KALRN,CAMK2D,ARHGEF25,ARHGEF1,DGKI,ARHGEF2,CDH2,ADGRG1,NGEF,ARHGEF6,CSF1,ARHGEF10,ARHGEF4,ARHGAP24,TIAM2,DNM2,DOCK2,RASGRP1,RASA4,ERBB2,DLC1,FOXM1,PSD2,STAMBP,RAPGEF1,IGF1,ITPKB,KITLG,NF1,MAPKAP1,PSD,IQSEC3,RASGRF1,RASGRF2,RDX,ARHGEF10L,ROBO1,RASA3,ITSN1,PREX2,ARHGEF40,TRIM67,IQSEC2,MCF2L2,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,PSD3,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" GO: Biological Process GO:0003012 muscle system process 1.17E-07 1.15E-03 5.73E-06 5.59E-05 123 430 "ABAT,ACTN2,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ANK2,PI16,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP2A2,MYOM1,BBS2,CFLAR,SGCE,CACNA1G,CACNA2D1,CACNB2,CACNG1,CALM1,CAMK2B,CAMK2D,CAMK2G,P2RX6,MYOM2,CHGA,CHRM1,CHRNB2,MYL6B,AKAP6,NOS1AP,DOCK4,HDAC4,DAPK3,DBN1,DMD,DMPK,DRD1,DTNA,EDN1,EDN3,EDNRA,EDNRB,SORBS3,CALCRL,RCSD1,MRVI1,FGF12,FLT1,SORBS1,PDLIM5,OGA,GAA,ATP8A2,MSTN,PPARGC1A,GNAO1,GPER1,NR3C1,GSN,GUCY1A1,HSP90AA1,HTR2A,MYLK2,IGF1,IL6ST,KCNA1,KCNH2,KCNMA1,MEF2C,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,NOS1,NPPA,OXTR,P2RY1,PDE4B,PDE4D,TMOD2,PGAM2,PIK3C2A,FXYD1,PPP3CA,PTAFR,RAP1GDS1,MYH14,KCNIP2,RYR1,RYR3,SCN2B,SCN4B,SCN7A,SMPD3,SMTN,SLC6A8,SLC8A1,SLC8A3,SLN,SCN3B,CAMTA2,SSTR2,SULF2,TACR1,TPCN2,TIAM1,HEY2,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,TRPC3,KCNE5,SSPN" GO: Biological Process GO:0007613 memory 1.17E-07 1.15E-03 5.73E-06 5.59E-05 48 125 "ASIC1,ADCY8,PLA2G6,ATP1A3,CALB1,KALRN,NOG,CHRNB2,SLC24A2,CNR1,CX3CR1,SHANK1,DRD1,RCAN1,RCAN2,FGF13,GRIA1,GRIN1,GRM7,HRH3,HTR2A,IGF1,KCNK2,NTRK2,OXTR,KCNK10,PPP3CB,PRKCZ,RELN,RASGRF1,S100B,SGK1,CPEB3,SLC8A2,SLC8A3,SHANK2,SORCS3,SNAP25,PLCB1,TAC1,TACR1,CUX2,CRTC1,VLDLR,SLC17A7,PAK5,NETO1,JPH3" GO: Biological Process GO:0030902 hindbrain development 1.19E-07 1.16E-03 5.74E-06 5.61E-05 60 170 "ABAT,NLGN4X,ASCL1,NCOA1,ATP2B2,CDK5R1,CDK5R2,CACNA1A,HAP1,PTBP2,CBLN1,CBS,NOG,GPR37L1,NRXN1,CNTN1,WHRN,SLC4A7,NCOR1,SEZ6L2,EN2,SEZ6,CEND1,DLC1,SEC24B,TBR1,GART,GBX2,PPARGC1A,GLI2,KDM2B,GRIN1,HNRNPK,IGF1,KNDC1,KCNC1,SMAD1,SMAD9,NEUROD1,NEUROD2,NFIX,OGDH,PAX6,SERPINE2,PROX1,PTN,RFX4,WLS,ATXN2,SMARCA4,FAIM2,MYO16,SSTR1,SSTR2,AGTPBP1,RPGRIP1L,RBFOX2,SEZ6L,NR2C2,WNT7A" GO: Biological Process GO:0008344 adult locomotory behavior 1.19E-07 1.17E-03 5.74E-06 5.61E-05 41 100 "APP,SPTBN4,ARRB2,ATP1A2,ATP1A3,CACNA1A,CACNB4,CLCN3,PUM1,DNM1,DRD1,SEZ6L2,EFNB3,SEZ6,EPS8,CEND1,FGF12,FGF14,CHL1,GLRB,GRIN1,GRIN2D,KCNJ10,KCNMA1,MAPT,ADAM22,OXR1,ATXN1,SCN8A,PREX2,SNCA,CNTN2,AGTPBP1,TMOD1,SEZ6L,TRH,TSC1,UCHL1,LGI4,ZIC1,PCDH15" GO: Biological Process GO:0051640 organelle localization 1.37E-07 1.34E-03 6.57E-06 6.42E-05 141 510 "ADORA3,SEMA6A,SYT13,DOC2A,AMPH,OGT,CDC42BPA,CNIH2,SHROOM2,CADPS,ATM,ATP2A2,BBS2,SYNJ1,SYNJ2,BTK,CACNA1A,HAP1,CANX,SYT6,ARHGEF2,CDC42,CDH2,CHGA,NRXN1,MYRIP,SEC24C,FEZ1,RIMS4,RIMS2,SNPH,RIMS3,DCTN1,CNIH3,MAGI2,BLOC1S6,SEC16A,DMD,DNM1,TRAPPC9,DYNC1I1,DNM2,DPYSL2,PDCD6IP,SYT15,RASGRP1,DCTN4,STX2,EYA1,F5,F8,SEC24B,FER,KIAA1109,FGF14,FGR,ANKFY1,SYT3,DCTN2,TACC2,SYT17,CPLX2,CPLX1,PCDH17,PSRC1,PCLO,GRIA1,GRIK5,KIF3A,ATCAY,MYLK2,DOCK7,C2CD4C,KIT,SYTL4,MAP4,MAP6,MAPT,SYT9,BLOC1S2,MYO5A,MYO7A,NEFH,NUMA1,OPA1,OPHN1,P2RX7,PAX6,PDPK1,NLGN3,PIK3CD,GPSM2,PACSIN1,PRKCZ,SYTL2,PTK2,SPDL1,RAB3A,LRRK2,SYNDIG1,STX1B,AP1AR,ITSN1,SH3GL2,NLGN1,SEC31A,RPH3A,RAB3GAP1,NAPB,SLIT1,CDK5RAP2,RIMS1,SNAP25,SNCA,KIF13A,KIF1B,CLASP2,STX1A,STXBP1,SYT11,SYNE2,SYN1,SYT1,ANKRD28,SYT4,SYT5,TACC1,TCF7L2,CLASP1,SYNE1,PARD3,UCHL1,GORASP1,LAT2,WNT7A,XPO1,TRIM9,FMN2,SPIRE1,C12orf4,AP3B2" GO: Biological Process GO:0051899 membrane depolarization 1.39E-07 1.36E-03 6.65E-06 6.49E-05 42 104 "ADORA2A,ANK2,ANK3,SHTN1,ATP1A2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CAMK2D,CCK,CHRNA4,CHRNB2,EDN1,CACNG2,RACK1,FGF12,FHL1,OGA,GRIK1,CACFD1,KCNH2,HCN1,P2RX7,NALCN,PRKCZ,PPP2R3C,LRRK2,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A1,SCN3B,TPCN2" GO: Biological Process GO:0007422 peripheral nervous system development 1.47E-07 1.44E-03 7.00E-06 6.84E-05 35 80 "ASIC2,AGT,PRX,ADGRB1,ADGRB2,ARHGEF10,PLXNA4,DMD,MED12,EDNRB,HEYL,EGR3,ERBB2,ETV1,HAPLN2,HNRNPK,LAMA2,ADAM22,NEFH,NF1,NTRK2,SERPINI1,PMP22,FA2H,POU3F2,SH3TC2,SOX8,SCN8A,SIRT2,SOX10,NFASC,DICER1,PARD3,UGT8,LGI4" GO: Biological Process GO:0006814 sodium ion transport 1.48E-07 1.45E-03 7.00E-06 6.84E-05 72 218 "ASIC2,ASIC1,ADRB2,SLC24A4,AGT,ANK3,SHROOM2,SPTBN4,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,HCN2,CAMK2D,SLC5A11,ASIC3,SLC24A2,STOML1,CNTN1,SLC4A7,SLC4A8,KLHL3,DMD,DMPK,DNM2,SGK2,SLC9B2,FGF12,FGF14,AHCYL1,GNAS,KCNK1,NOS1,HCN1,P2RX7,SLC10A4,SERPINE2,NALCN,FXYD1,NKAIN4,NKAIN1,SLC6A15,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SGK1,SLC6A8,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC12A2,SLC20A2,SLC22A4,SCN3B,NKAIN2,PLCB1,TRPM2,SGK3,SLC13A3,SLC38A1,SLC17A7,WNK3,WNK2,SLC17A6,SLC4A10" GO: Biological Process GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.71E-07 1.68E-03 8.05E-06 7.86E-05 49 130 "SEMA6A,SEMA7A,SEMA4G,ARHGDIA,DACT3,CDK5R1,LDLRAD4,ARHGEF1,SLIT2,NGEF,AATK,DCC,SEMA3D,DMTN,CDKL3,FGF13,MAD2L2,SEMA6C,SEMA4D,CIT,LINGO1,MAG,MBP,MT3,OMG,NLGN3,SEMA5B,PPP3CA,PTK2,PTPRO,AP1AR,SALL1,SEMA6D,DRAXIN,FUZ,NLGN1,SLIT1,SPP1,SPART,PBLD,KANK1,SEMA4A,TGFBR3,TNR,TTC3,GORASP1,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0060292 long-term synaptic depression 1.75E-07 1.72E-03 8.20E-06 8.01E-05 17 26 "ABHD6,ADORA1,CD38,DGKI,SLC24A2,PICK1,DRD1,PTK2B,STAU2,GRIA1,KCNB1,MAPT,PPP1R9A,SHANK2,SORCS3,IQSEC2,STXBP1" GO: Biological Process GO:0022037 metencephalon development 1.88E-07 1.85E-03 8.79E-06 8.58E-05 47 123 "ABAT,NLGN4X,ASCL1,NCOA1,ATP2B2,CDK5R1,CDK5R2,CACNA1A,HAP1,PTBP2,CBLN1,CBS,NRXN1,CNTN1,WHRN,SLC4A7,NCOR1,SEZ6L2,SEZ6,CEND1,SEC24B,GART,GBX2,PPARGC1A,GLI2,GRIN1,HNRNPK,KNDC1,KCNC1,NEUROD1,NEUROD2,NFIX,OGDH,SERPINE2,PROX1,PTN,RFX4,ATXN2,FAIM2,MYO16,SSTR1,SSTR2,AGTPBP1,RPGRIP1L,SEZ6L,NR2C2,WNT7A" GO: Biological Process GO:0008038 neuron recognition 2.09E-07 2.05E-03 9.71E-06 9.49E-05 21 37 "DSCAML1,APP,CDK5R1,CNR1,CNTNAP2,NTM,DSCAM,EFNB3,CELSR3,FOXG1,GAP43,NRCAM,OPCML,PTPRZ1,FEZF2,CRTAC1,ROBO1,ROBO2,ROBO3,CNTN2,RTN4" GO: Biological Process GO:0048708 astrocyte differentiation 2.17E-07 2.12E-03 1.00E-05 9.79E-05 32 71 "ADORA2A,AGT,BIN1,NOG,GPR37L1,DRD1,EGFR,FGFR3,DLL3,GFAP,HES5,IL6ST,MAG,MBD1,MT3,MYCN,NF1,NFIX,NKX2-2,NTRK3,PAX6,SERPINE2,PLP1,POU3F2,MAPK3,SOX8,S100B,SOX6,TAL1,CNTN2,TLR4,NR2E1" GO: Biological Process GO:0048017 inositol lipid-mediated signaling 2.21E-07 2.17E-03 1.02E-05 9.95E-05 70 212 "ADORA3,AGT,OGT,TNRC6C,FGF17,SYNJ1,CA8,CD86,NRG2,NCOR1,CSF1R,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,STAMBP,FYN,GAB1,TNRC6A,GPER1,GSN,TNFAIP8L3,HTR2A,IGF1,JAK2,KIT,PIK3AP1,KITLG,MOV10,NF1,NTRK2,PIRT,PDGFRA,PDPK1,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,PLXNB1,MAPKAP1,PPP2R5C,MAPK3,RELN,PTAFR,PTK2,PTPN13,PRR5L,PREX2,SIRT2,MYO16,UNC5B,MLST8,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1,RICTOR" GO: Biological Process GO:0021988 olfactory lobe development 2.28E-07 2.24E-03 1.05E-05 1.02E-04 22 40 "SEMA7A,SLIT2,LHX2,CSF1R,DPYSL2,EFNA2,ERBB4,FGFR1,SALL3,OGDH,PAX6,CRTAC1,ROBO1,ROBO2,LRRK2,SALL1,ARX,SLIT1,AGTPBP1,RPGRIP1L,DICER1,NR2E1" GO: Biological Process GO:0019233 sensory perception of pain 2.42E-07 2.38E-03 1.11E-05 1.08E-04 50 135 "ADORA1,ADRB2,PRX,ARRB2,CACNA1A,CACNA1B,CACNA1E,CCK,CCKBR,ASIC3,CHRNA4,CHRNB2,CNR1,DLG2,EDN1,EDNRA,EDNRB,EPHB1,FCGR3A,FGFR1,FYN,GRIN1,GRIN2D,GRM1,GRM3,GRM8,HTR2A,KCNA1,KCNA2,KCND2,KCNJ10,NCAM1,NOS1,OPRL1,P2RX7,P2RY1,PENK,RETREG1,MAPK3,PTAFR,TMEM100,KCNIP3,SCN3A,SCN3B,TAC1,TACR1,SPX,TLR4,UCHL1,RTN4" GO: Biological Process GO:0007155 cell adhesion 2.54E-07 2.49E-03 1.15E-05 1.13E-04 357 1530 "TTYH1,ABAT,DGCR6,ACHE,ACTN1,ACTN2,DSCAML1,ADORA2A,ADRB2,NLGN4X,PCDH19,AGT,C1QTNF1,ALCAM,SRPX,PCDH10,ANK3,PPFIA2,PPFIA1,PKP4,CNTNAP1,APC,EPB41L5,APLP1,GPAM,APP,CASK,ARHGAP5,ARHGDIA,ARHGDIG,PCDHGB4,CHRD,ASTN1,ATP2A2,CADM3,ADAM23,ADAM15,AZGP1,ADGRB1,MPDZ,NRP2,BLM,BMP7,CDK5R1,DST,ARHGEF7,SGCE,DDR1,CACNB4,CBLN1,CLDN10,CD86,CDC42,CDH2,CDH8,CDH10,CDH18,MAGI1,ADGRG1,SOCS6,JAM2,TAOK2,SLIT2,NRXN3,NRXN1,NRXN2,CNTN1,ABI3BP,BAG4,NECTIN3,HAPLN1,NCOR1,CSF1,CSF3R,FEZ1,SUSD5,VCAN,NCAN,SOCS5,CNTNAP2,SDC3,CTNND1,CTNND2,CX3CR1,BOC,MYADM,DAPK3,SPOCK2,SIRPA,DBN1,NTM,DMD,CD99L2,CDON,DNM2,DOCK2,DSCAM,GNE,ECM2,DNAJB6,EDIL3,WDPCP,RASGRP1,EFNB3,CELSR3,EBI3,EGFR,EGR3,PLXNC1,SORBS3,CERCAM,DMTN,EPHA5,EPHB1,ERBB2,EFS,CDHR1,ADGRV1,PTK2B,DLC1,FCGR3A,TESK2,FER,MAD2L2,MEX3B,SEMA4D,SORBS1,NPTN,ATP2C1,CGREF1,FYN,MEGF11,MEGF10,CHL1,TMEM8B,SIGLEC8,DISC1,IGSF5,GCNT2,FREM1,PCDH17,MALT1,KIRREL3,LYVE1,RND1,GLI2,PCDH11X,GNAS,FERMT2,GP1BB,GPM6B,RAPGEF1,ADAMTS13,PTPRT,GSN,IL1RAPL1,BVES,HAS2,NCKAP1L,VSIG4,HAPLN2,HMGB1,NEGR1,HSP90AA1,IGF1,RBPJ,HES5,IL6ST,IL12A,ITGA7,ITGAM,ITGAV,ITPKB,JAK2,CDH20,KIFC3,KIT,L1CAM,LAMA2,LIG4,LIMS1,LMO1,LSAMP,MAG,KITLG,MKLN1,AFDN,MOG,CD200,COL28A1,CCDC80,ADAM22,CTNNA3,MYBPC1,NCAM1,NCAM2,NF1,NINJ2,NODAL,VWA2,NRCAM,DDR2,IGSF11,OLR1,OMG,OPCML,CLDN11,P2RX7,PAK3,CNTN3,PCDHGC3,PCDH8,PCDH9,PDE3B,PDGFRA,ENPP2,PDPK1,DUSP26,NLGN3,SERPINE2,SERPINI1,PIK3CD,PIK3R1,PKD1,PCDH18,PLXNB1,PLXNB3,MAPKAP1,RC3H2,SDK2,EPB41L4B,FAT3,PPARA,PPP3CA,PPP3CB,CEP41,PKN2,PRKCZ,EPDR1,MAPK7,DCHS2,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,STRC,FAT4,RAP1GAP,RDX,RET,ROBO1,KIRREL1,ROBO2,ROM1,GLDN,CNTNAP3,AP1AR,SATB1,SELL,NLGN4Y,FERMT1,FNDC3A,ST6GAL1,BCAN,NLGN1,CLSTN1,LIMS2,RADIL,SLC11A1,ELMO2,IGSF9B,PDZD2,SOX2,SPP1,NFASC,CLASP2,CLSTN2,SMOC1,SSPO,ERBIN,KANK1,STXBP1,AJAP1,JMJD6,PLCB1,SEMA4A,MLST8,UNC5D,CNTN2,ADGRL3,VWC2,TCF7,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,DICER1,ITGB3BP,THBS4,CDH22,TIAM1,RELL2,ICAM5,PARD3,TNR,TPM1,RGMB,TRO,TSC1,HEPACAM,CADM1,FLRT2,FLRT1,VAV1,P2RY12,RICTOR,XRCC4,PCDH20,ZBTB16,CADM2,SIGLEC10,PCDH15,DOCK8,NLRP3,SSPN" GO: Biological Process GO:0017157 regulation of exocytosis 2.70E-07 2.65E-03 1.22E-05 1.19E-04 68 205 "ABR,ADORA3,PLA2G6,SYT13,DOC2A,CADPS,ATP2A2,CACNA1I,CACNA1G,CDK5R2,CACNA1A,HAP1,SYT6,CBARP,RAB3C,RAB26,RIMS4,RIMS2,RIMS3,PDCD6IP,SYT15,PRAM1,FER,FGR,SYT3,SYT17,CPLX2,CPLX1,PCLO,RAPGEF4,GRIK5,IL1RAPL1,C2CD4C,KCNB1,STXBP5,SYTL4,SYT9,SCAMP5,MYO5A,NCAM1,PDPK1,SYTL2,PTAFR,RAB3A,LRRK2,STX1B,SMPD3,NLGN1,RPH3A,RAB3GAP1,NAPB,LGI3,RIMS1,SNCA,CLASP2,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,CLASP1,ATP13A2,VSNL1,TRIM9,C12orf4" GO: Biological Process GO:0048015 phosphatidylinositol-mediated signaling 2.71E-07 2.65E-03 1.22E-05 1.19E-04 69 209 "ADORA3,AGT,OGT,TNRC6C,FGF17,SYNJ1,CA8,CD86,NRG2,NCOR1,CSF1R,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,STAMBP,FYN,GAB1,TNRC6A,GPER1,GSN,HTR2A,IGF1,JAK2,KIT,PIK3AP1,KITLG,MOV10,NF1,NTRK2,PIRT,PDGFRA,PDPK1,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,PLXNB1,MAPKAP1,PPP2R5C,MAPK3,RELN,PTAFR,PTK2,PTPN13,PRR5L,PREX2,SIRT2,MYO16,UNC5B,MLST8,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1,RICTOR" GO: Biological Process GO:0050885 neuromuscular process controlling balance 2.71E-07 2.66E-03 1.22E-05 1.19E-04 30 65 "ABR,ADCY5,CNTNAP1,APP,PDE8B,ATP2B2,CACNA1A,CAMK2B,NRXN1,TPP1,IGDCC3,DLG4,SHANK1,USH1C,GAA,JPH4,NKX6-2,GRIN2C,KCNMA1,MYO5A,MYO7A,GPR88,SLC1A3,ANKFN1,SOX2,CAMTA1,TNR,RBFOX2,PCDH15,JPH3" GO: Biological Process GO:0051093 negative regulation of developmental process 2.77E-07 2.72E-03 1.24E-05 1.21E-04 228 914 "ABR,ADCY6,AXIN2,ADRB2,AGT,NR0B1,DISP3,SEMA6A,AMH,SEMA7A,PI16,APBB1,APC,APP,SEMA4G,ARHGDIA,ARNTL,ASCL1,DACT3,CHRD,ADGRB1,ADGRB2,ADGRB3,BBS2,CFLAR,BMP7,CDK5R1,MTMR2,C1QC,RAB29,LDLRAD4,CAPN3,RUNX1T1,KRIT1,USP2,RGN,CD86,ARHGEF1,CBFA2T2,ARHGEF2,EVI5L,NOG,GPR37L1,ADGRG1,SLIT2,NGEF,FBXO7,TJP2,MAP4K4,CRMP1,NCOR2,ABCG1,AATK,SOCS5,CST3,CMTM5,PHF14,CX3CR1,HDAC9,HDAC4,BRINP1,DCC,KIAA0319,NTM,DLX1,FAM57B,EDNRB,SEMA3D,OLIG2,DMTN,LRRC17,SEZ6,ERBB2,ERBB4,CDKL3,CEND1,ADGRV1,PTK2B,EFEMP1,PRMT5,OLFM1,FGF13,FGFR1,FGFR3,MAD2L2,FOXG1,FOXM1,SEMA6C,FOXO3,SEMA4D,DLL3,NRG3,NKX6-2,MSTN,GFAP,USP19,PPARGC1A,GLI2,GNAS,LILRB4,GPER1,STMN2,C1QL4,PLPP7,CIT,SOX21,LINGO1,HMGB1,HNRNPK,IGF1,NKD1,RBPJ,HES5,ITGAV,ITPKB,KCNK2,LIMS1,LMO2,MAG,MAP4,MBD1,MBP,MEIS1,MEIS2,MT3,RSPO2,MDGA1,MYCN,NEUROD2,NF1,NFE2L2,NKX2-2,NODAL,NPR2,NTRK3,NUCB2,OMG,PAX6,PBX1,PDE3B,GPR173,NLGN3,SEMA5B,PIK3R1,PMP22,TNPO2,FAT3,PPARA,MED1,PPP3CA,PRKACB,PTCH1,PTHLH,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,CEP97,RAP1GAP,FEZF2,RFX4,ROBO1,ROBO2,RORB,FBXW7,SOX8,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,FUZ,NLGN1,LIMS2,SIRT2,SLIT1,ZKSCAN3,CDK5RAP2,IFT122,SOX2,SOX3,SOX11,SOX15,SPP1,RAP1GAP2,SPART,PBLD,CLASP2,MESP1,KANK1,SEMA4A,CNTN2,WWC1,TCF4,TCF7L2,ZEB1,CLASP1,TEK,DICER1,SIRT1,ZFPM2,GPR161,TGFBR3,HHIP,THBS4,TIE1,HEY1,TLL2,TLR4,NR2E1,HEY2,TNR,TTC3,TTPA,EIF4ENIF1,AMOT,GORASP1,P2RY12,WNT7A,ZBTB16,RGMA,TMEM178A,SEMA3B,ITM2C,FZD3,RTN4" GO: Biological Process GO:0022610 biological adhesion 2.97E-07 2.91E-03 1.32E-05 1.29E-04 359 1542 "TTYH1,ABAT,DGCR6,ACHE,ACTN1,ACTN2,DSCAML1,ADORA2A,ADRB2,NLGN4X,PCDH19,AGT,C1QTNF1,ALCAM,SRPX,PCDH10,ANK3,PPFIA2,PPFIA1,PKP4,CNTNAP1,APC,EPB41L5,APLP1,GPAM,APP,CASK,ARHGAP5,ARHGDIA,ARHGDIG,PCDHGB4,CHRD,ASTN1,ATP2A2,CADM3,ADAM23,ADAM15,AZGP1,ADGRB1,MPDZ,NRP2,BLM,BMP7,CDK5R1,DST,ARHGEF7,SGCE,DDR1,CACNB4,CBLN1,CLDN10,CD86,SCARB1,CD81,CDC42,CDH2,CDH8,CDH10,CDH18,MAGI1,ADGRG1,SOCS6,JAM2,TAOK2,SLIT2,NRXN3,NRXN1,NRXN2,CNTN1,ABI3BP,BAG4,NECTIN3,HAPLN1,NCOR1,CSF1,CSF3R,FEZ1,SUSD5,VCAN,NCAN,SOCS5,CNTNAP2,SDC3,CTNND1,CTNND2,CX3CR1,BOC,MYADM,DAPK3,SPOCK2,SIRPA,DBN1,NTM,DMD,CD99L2,CDON,DNM2,DOCK2,DSCAM,GNE,ECM2,DNAJB6,EDIL3,WDPCP,RASGRP1,EFNB3,CELSR3,EBI3,EGFR,EGR3,PLXNC1,SORBS3,CERCAM,DMTN,EPHA5,EPHB1,ERBB2,EFS,CDHR1,ADGRV1,PTK2B,DLC1,FCGR3A,TESK2,FER,MAD2L2,MEX3B,SEMA4D,SORBS1,NPTN,ATP2C1,CGREF1,FYN,MEGF11,MEGF10,CHL1,TMEM8B,SIGLEC8,DISC1,IGSF5,GCNT2,FREM1,PCDH17,MALT1,KIRREL3,LYVE1,RND1,GLI2,PCDH11X,GNAS,FERMT2,GP1BB,GPM6B,RAPGEF1,ADAMTS13,PTPRT,GSN,IL1RAPL1,BVES,HAS2,NCKAP1L,VSIG4,HAPLN2,HMGB1,NEGR1,HSP90AA1,IGF1,RBPJ,HES5,IL6ST,IL12A,ITGA7,ITGAM,ITGAV,ITPKB,JAK2,CDH20,KIFC3,KIT,L1CAM,LAMA2,LIG4,LIMS1,LMO1,LSAMP,MAG,KITLG,MKLN1,AFDN,MOG,CD200,COL28A1,CCDC80,ADAM22,CTNNA3,MYBPC1,NCAM1,NCAM2,NF1,NINJ2,NODAL,VWA2,NRCAM,DDR2,IGSF11,OLR1,OMG,OPCML,CLDN11,P2RX7,PAK3,CNTN3,PCDHGC3,PCDH8,PCDH9,PDE3B,PDGFRA,ENPP2,PDPK1,DUSP26,NLGN3,SERPINE2,SERPINI1,PIK3CD,PIK3R1,PKD1,PCDH18,PLXNB1,PLXNB3,MAPKAP1,RC3H2,SDK2,EPB41L4B,FAT3,PPARA,PPP3CA,PPP3CB,CEP41,PKN2,PRKCZ,EPDR1,MAPK7,DCHS2,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRD,PTPRG,PTPRO,PTPRZ1,STRC,FAT4,RAP1GAP,RDX,RET,ROBO1,KIRREL1,ROBO2,ROM1,GLDN,CNTNAP3,AP1AR,SATB1,SELL,NLGN4Y,FERMT1,FNDC3A,ST6GAL1,BCAN,NLGN1,CLSTN1,LIMS2,RADIL,SLC11A1,ELMO2,IGSF9B,PDZD2,SOX2,SPP1,NFASC,CLASP2,CLSTN2,SMOC1,SSPO,ERBIN,KANK1,STXBP1,AJAP1,JMJD6,PLCB1,SEMA4A,MLST8,UNC5D,CNTN2,ADGRL3,VWC2,TCF7,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,DICER1,ITGB3BP,THBS4,CDH22,TIAM1,RELL2,ICAM5,PARD3,TNR,TPM1,RGMB,TRO,TSC1,HEPACAM,CADM1,FLRT2,FLRT1,VAV1,P2RY12,RICTOR,XRCC4,PCDH20,ZBTB16,CADM2,SIGLEC10,PCDH15,DOCK8,NLRP3,SSPN" GO: Biological Process GO:0061003 positive regulation of dendritic spine morphogenesis 3.08E-07 3.02E-03 1.36E-05 1.33E-04 13 17 "CAPRIN2,KALRN,CAMK2B,DBN1,BAIAP2,STAU2,ITPKA,PAK3,RELN,CUX2,TIAM1,BHLHB9,LRP8" GO: Biological Process GO:0050771 negative regulation of axonogenesis 3.21E-07 3.15E-03 1.41E-05 1.38E-04 32 72 "SEMA6A,SEMA7A,SEMA4G,ARHGDIA,CDK5R1,ARHGEF1,SLIT2,AATK,DCC,SEMA3D,CDKL3,FGF13,SEMA6C,SEMA4D,LINGO1,MAG,MBP,MT3,OMG,SEMA5B,PTK2,PTPRO,SEMA6D,DRAXIN,SLIT1,SPP1,SPART,SEMA4A,TNR,RGMA,SEMA3B,RTN4" GO: Biological Process GO:1903530 regulation of secretion by cell 3.33E-07 3.27E-03 1.46E-05 1.43E-04 191 744 "ABAT,ABR,ASIC1,ACHE,ADCY5,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,SYT13,DOC2A,APBB1,GPAM,MADD,ARNTL,ARRB1,CADPS,PDE8B,ATP2A2,ARHGEF7,CACNA1I,CACNA1G,C5,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,HAP1,CAMK2A,SYT6,BRSK2,CCK,CCKBR,CD38,CACNA2D2,CBARP,CHGA,CHRNA4,RAB3C,CHRNB2,NRXN1,MAP4K4,RAB26,CNR1,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SNCAIP,CSF1R,RIMS4,RIMS2,RIMS3,C2CD2L,DPYSL2,PDCD6IP,DNM1L,EDN1,EDN3,SYT15,RASGRP1,SIDT2,EGFR,EPHA5,PRAM1,FER,FGFR1,FGR,SYT3,TRIM16,OGA,GABBR1,GALR1,SYT17,CPLX2,CPLX1,GCK,ARFIP1,GDF9,GLUL,KCNMB4,GNAS,GPER1,PCLO,RAPGEF4,GRIK5,NR3C1,GRM7,GRM8,IL1RAPL1,HRH3,HMGB1,HMGCR,HTR2A,ICA1,IGF1,C2CD4C,JAK2,KCNA2,KCNB1,KCNC2,KCNJ11,STXBP5,SYTL4,MAOB,SYT9,MEF2C,SCAMP5,MYO5A,MYT1,NCAM1,NELL2,NEUROD1,NF1,NNAT,NOS1,CLEC9A,NTRK2,NUCB2,OXTR,P2RX7,P2RY1,PAX6,PDE1C,PDE3B,PDPK1,PFKFB2,PLCD1,PPP3CA,PPP3CB,PRKCB,PRKCZ,SYTL2,PTAFR,RAB3A,RFX3,LRRK2,LGR4,WLS,STX1B,SMPD3,IL17RB,SCG5,PPP1R9A,MYO18A,SYBU,NLGN1,RPH3A,RAB3GAP1,NAPB,LGI3,RIMS1,SNAP25,SNCA,SOX11,CLASP2,STX1A,STXBP1,SYT11,ABCC8,PLCB1,SYN1,SYT1,SYT4,SYT5,TAC1,TACR1,TCF7L2,CLASP1,TEK,ATP13A2,SIRT1,TIAM1,TLR4,ZNF384,TRH,STXBP4,TRPM2,CADM1,VSNL1,P2RY12,TRIM9,C12orf4,RTN4,NLRP3" GO: Biological Process GO:0040007 growth 3.40E-07 3.33E-03 1.48E-05 1.45E-04 265 1091 "SLC25A25,NDRG3,SLITRK1,ADD1,SLC12A5,ADRA1B,ADRB2,NLGN4X,AGT,SEMA6A,ALCAM,LTBP4,UNC79,AMH,SEMA7A,PI16,APBA2,APBB1,APBB2,EPB41L5,GPAM,DGKD,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,CAPRIN2,DACT3,CCAR2,ADAM15,AZGP1,BBS2,NRP2,CFLAR,BMP7,BMPR1B,CDK5R1,FUBP1,FOXK1,CACNA1A,DDR1,CAMK2D,CAPN3,MAP7,CD38,CD81,CDK11B,SEPT7,CDC42,DCLK1,LGI1,LARGE1,NOG,CACNA2D2,SOCS6,TAOK2,SLIT2,LHX2,KMT2C,CPNE6,NIPBL,AKAP6,COL9A1,NCOR1,AATK,CSF1,TENM4,SOCS5,PLXNA4,CTH,RIMS2,KIF26A,INTS1,IST1,DBN1,DCC,ZEB2,MAGI2,MED12,DNM2,DPYSL2,DSCAM,EDN1,SGK2,SEMA3D,EGFR,PLXNC1,EIF4G2,PLEKHA1,ING4,RASGRP2,ERBB2,ERBB4,ERCC2,CDKL3,CD320,NRN1,ACSL4,PTK2B,RACK1,KIAA1109,FGF1,OLFM1,FGF13,FGFR1,FGFR3,MAD2L2,FHL1,UBE2E3,IP6K2,FOXM1,SEMA6C,FOXO3,SEMA4D,SYT3,PDLIM5,CELF1,CGREF1,CSPG5,NRG3,GAP43,TMEM8B,SYT17,DISC1,ATP8A2,MSTN,GDF9,GHR,BRD8,GLI2,KDM2B,GNAS,GNG4,PSRC1,GPD2,NR3C1,GSN,FAM107A,MAEL,IGFBPL1,HNRNPK,IRF8,IFI16,IGF1,IGFBP1,NKD1,RBPJ,IL6R,ITGAV,KCNK2,L1CAM,SMAD1,MAPT,MEF2C,CPNE9,MT1M,MT3,N6AMT1,RSPO2,MYH6,NACA,NCAM1,NEK1,NELL2,NINJ2,NPPA,NRCAM,NTRK3,DDR2,IGSF11,OMG,PDE4D,NLGN3,SERPINE2,SEMA5B,PKM,FTO,PLXNB1,RC3H2,LRP12,ING3,POU3F2,MED1,PPP3CB,PRKCB,PRKCZ,PROX1,KLK6,PTCH1,PTHLH,PTK2,PEX5,USP47,RBBP6,ROBO1,RXRA,RMI1,SAFB,SALL1,SEMA6D,SBF1,DRAXIN,ATXN2,IL17RB,SGK1,ARX,CLSTN1,SLC1A2,SLC12A2,SLIT1,EPC1,SMARCA4,RIMS1,MBD5,WDTC1,SOX2,SOX10,SOX15,SP2,SPP1,TSPYL2,SPART,CLASP2,MESP1,EPB41L3,ERBIN,PLCB1,SYT1,COBL,SYT4,SEMA4A,TAF9,WWC1,TCF7L2,TNS2,SIK3,DICER1,SIRT1,LEFTY2,ZMAT3,TGFBR3,TIAM1,TLL2,HEY2,TNR,TRO,SGK3,HEPACAM,CADM1,UBE3A,FLRT1,WNT7A,WRN,ATP6V0E2,NDRG4,RGMA,SEMA3B,PCDH15,HRASLS,RTN4,PAK5,VANGL2,SOCS4,SLC4A10" GO: Biological Process GO:0051046 regulation of secretion 3.51E-07 3.44E-03 1.52E-05 1.49E-04 203 800 "ABAT,ABR,ASIC1,ACHE,ADCY5,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,SYT13,DOC2A,APBB1,GPAM,MADD,ARNTL,ARRB1,CADPS,PDE8B,ATP2A2,ARHGEF7,CACNA1I,CACNA1G,C5,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,HAP1,CAMK2A,SYT6,BRSK2,CCK,CCKBR,CD38,CACNA2D2,CBARP,CHGA,CHRNA4,RAB3C,CHRNB2,NRXN1,MAP4K4,RAB26,CNR1,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SNCAIP,CSF1R,RIMS4,RIMS2,RIMS3,C2CD2L,DPYSL2,PDCD6IP,DNM1L,EDN1,EDN3,EDNRB,SYT15,RASGRP1,SIDT2,EGFR,EPHA5,ACSL4,PRAM1,FER,FGFR1,FGR,SYT3,TRIM16,OGA,GABBR1,GALR1,SYT17,CPLX2,CPLX1,GCK,ARFIP1,GDF9,GLUL,KCNMB4,GNAS,GPER1,PCLO,RAPGEF4,GRIK1,GRIK5,NR3C1,GRM7,GRM8,IL1RAPL1,HRH3,HMGB1,HMGCR,HTR2A,ICA1,IGF1,SCIN,C2CD4C,JAK2,KCNA2,KCNB1,KCNC2,KCNJ11,STXBP5,SYTL4,MAOB,SYT9,MEF2C,SCAMP5,MYO5A,MYO6,MYT1,NCAM1,NELL2,NEUROD1,NF1,NNAT,NOS1,CLEC9A,NTRK2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PDE1C,PDE3B,PDPK1,PFKFB2,PLCD1,PPP3CA,PPP3CB,PRKCB,PRKCZ,MAPK9,SYTL2,PTAFR,RAB3A,RFX3,LRRK2,LGR4,WLS,STX1B,SMPD3,IL17RB,SGK1,SCG5,PPP1R9A,MYO18A,SYBU,NLGN1,RPH3A,SLC6A1,RAB3GAP1,NAPB,LGI3,RIMS1,SNAP25,SNCA,SOX11,CLASP2,STX1A,STXBP1,SYT11,ABCC8,PLCB1,SYN1,SYT1,SYT4,SYT5,TAC1,TACR1,TCF7L2,CLASP1,TEK,ATP13A2,SIRT1,SPX,TIAM1,TLR4,ZNF384,TRH,STXBP4,TRPM2,CADM1,VSNL1,P2RY12,TRIM9,WNK1,WNK3,C12orf4,RTN4,NLRP3" GO: Biological Process GO:0021772 olfactory bulb development 3.86E-07 3.79E-03 1.65E-05 1.61E-04 21 38 "SLIT2,LHX2,CSF1R,DPYSL2,EFNA2,ERBB4,FGFR1,SALL3,OGDH,PAX6,CRTAC1,ROBO1,ROBO2,LRRK2,SALL1,ARX,SLIT1,AGTPBP1,RPGRIP1L,DICER1,NR2E1" GO: Biological Process GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 3.86E-07 3.79E-03 1.65E-05 1.61E-04 21 38 "SYT13,DOC2A,ATP2A2,CACNA1A,SYT6,RIMS2,SYT15,SYT3,SYT17,C2CD4C,SYTL4,SYT9,SYTL2,RPH3A,RAB3GAP1,RIMS1,SNAP25,SYT11,SYT1,SYT4,SYT5" GO: Biological Process GO:0032291 axon ensheathment in central nervous system 3.87E-07 3.80E-03 1.65E-05 1.61E-04 12 15 "MYRF,CLU,TENM4,ERCC2,FGFR3,NKX6-2,HES5,KCNJ10,OMG,PLP1,FA2H,CNTN2" GO: Biological Process GO:0022010 central nervous system myelination 3.87E-07 3.80E-03 1.65E-05 1.61E-04 12 15 "MYRF,CLU,TENM4,ERCC2,FGFR3,NKX6-2,HES5,KCNJ10,OMG,PLP1,FA2H,CNTN2" GO: Biological Process GO:0021549 cerebellum development 3.95E-07 3.88E-03 1.67E-05 1.63E-04 43 111 "ABAT,NLGN4X,NCOA1,ATP2B2,CDK5R1,CDK5R2,CACNA1A,HAP1,PTBP2,CBLN1,CBS,NRXN1,CNTN1,WHRN,NCOR1,SEZ6L2,SEZ6,CEND1,GART,GBX2,PPARGC1A,GLI2,HNRNPK,KNDC1,KCNC1,NEUROD1,NEUROD2,NFIX,OGDH,SERPINE2,PROX1,PTN,RFX4,ATXN2,FAIM2,MYO16,SSTR1,SSTR2,AGTPBP1,RPGRIP1L,SEZ6L,NR2C2,WNT7A" GO: Biological Process GO:0006936 muscle contraction 3.95E-07 3.88E-03 1.67E-05 1.63E-04 102 348 "ABAT,ACTN2,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ANK2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP2A2,MYOM1,BBS2,CACNA1G,CACNA2D1,CACNB2,CACNG1,CALM1,CAMK2D,P2RX6,MYOM2,CHGA,CHRM1,CHRNB2,MYL6B,AKAP6,NOS1AP,DOCK4,HDAC4,DAPK3,DBN1,DMD,DMPK,DRD1,DTNA,EDN1,EDN3,EDNRA,EDNRB,SORBS3,CALCRL,RCSD1,MRVI1,FGF12,FLT1,SORBS1,GAA,ATP8A2,GNAO1,GPER1,GUCY1A1,HSP90AA1,HTR2A,MYLK2,KCNA1,KCNH2,KCNMA1,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,NOS1,NPPA,OXTR,PDE4B,PDE4D,TMOD2,PGAM2,PIK3C2A,FXYD1,PTAFR,RAP1GDS1,MYH14,KCNIP2,RYR1,RYR3,SCN2B,SCN4B,SCN7A,SMPD3,SMTN,SLC6A8,SLC8A1,SLC8A3,SCN3B,SSTR2,SULF2,TACR1,TPCN2,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,KCNE5,SSPN" GO: Biological Process GO:0060074 synapse maturation 4.19E-07 4.11E-03 1.76E-05 1.72E-04 15 22 "CAMK2B,NEURL1,NRXN3,NRXN1,SHANK1,SEZ6L2,SEZ6,ERBB4,DISC1,HNRNPK,NEUROD2,NFIA,PALM,RELN,SEZ6L" GO: Biological Process GO:0046903 secretion 4.37E-07 4.29E-03 1.83E-05 1.79E-04 293 1228 "SERPINA3,ABAT,ABR,SYN3,ASIC1,ACHE,ACTN1,ACTN2,ADCY5,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,ANK1,PPFIA4,PPFIA2,PPFIA1,APBB1,UPRT,GPAM,PPFIA3,APP,MADD,CASK,ARNTL,ARRB1,CADPS,PDE8B,NCOA1,ATP2A2,ATP2B2,SYNJ1,ARHGEF7,BTK,CACNA1I,CACNA1G,C5,BAIAP3,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,DDR1,CACNB4,CALM1,HAP1,CAMK2A,CAMK2G,CANX,SYT6,BRSK2,CBLN1,CCK,CCKBR,CD38,NEURL1,DGKI,CDO1,CACNA2D2,CBARP,CHGA,CHRM1,CHRNA4,RAB3C,CHRNB2,SLC22A6,NRXN3,NRXN1,NRXN2,CLU,MAP4K4,RAB26,CNR1,AKAP5,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SLC32A1,NCOR1,SNCAIP,CSF1R,RIMS4,PNPLA8,RIMS2,SNPH,RIMS3,SCRN1,C2CD2L,BLOC1S6,SNAP91,DPYSL2,PDCD6IP,DNM1L,EDN1,EDN3,EDNRA,EDNRB,SYT15,RASGRP1,SIDT2,OPTN,EGFR,DMTN,EPHA5,RABEPK,STX2,ERBB4,F5,F8,ACSL4,PRAM1,FER,FGFR1,FGR,VTI1B,SYT3,TRIM16,BRSK1,TVP23A,OGA,GABBR1,TRAF3IP2,ILDR2,GAD1,GAD2,BRPF3,GALR1,SYT17,STARD10,CPLX2,CPLX1,GCK,ARFIP1,GDF9,GLS,GLUL,KCNMB4,GNAS,GPER1,PCLO,RAPGEF4,GRIK1,GRIK5,NR3C1,GRM2,GRM7,GRM8,IL1RAPL1,HRH3,HMGB1,HMGCR,HTR2A,ICA1,IGF1,RBPJ,SCIN,C2CD4C,JAK2,KCNA2,KCNB1,KCNC2,KCNJ11,KCNMA1,KIT,STXBP5,LAMP2,SYTL4,MAOB,SYT9,MEF2C,SCAMP5,SCG3,MYO5A,MYO6,MYT1,NCAM1,NELL2,NEUROD1,NF1,NNAT,NOS1,CLEC9A,NTRK2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PCSK5,PDE1C,PDE3B,PDPK1,PFKFB2,SERPINE2,PIK3C2A,PIK3CD,PLCD1,MED1,PPP3CA,PPP3CB,PRKCB,PRKCZ,MAPK9,SYTL2,PTAFR,PTPRN,PTPRN2,RAB3A,RFX3,LRRK2,LGR4,WLS,STX1B,SMPD3,IL17RB,SGK1,SCG5,PPP1R9A,MYO18A,SYBU,NLGN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC1A7,SLC6A1,SLC6A9,RAB3GAP1,NAPB,LGI3,SLC22A4,RIMS1,SNAP25,SNCA,SOX11,CLASP2,STX1A,STXBP1,SYT11,ABCC8,VAMP1,PLCB1,SYN1,SYN2,SYT1,SYT4,SYT5,TAC1,TACR1,EXOC7,TCF7L2,CLASP1,TEK,ATP13A2,TF,SIRT1,SPX,LEFTY2,TIAM1,TLR4,TPD52,ZNF384,TRH,STXBP4,TRPC1,TRPM2,CADM1,VGF,LMF1,VSNL1,P2RY12,LAT2,WNT7A,TRIM9,WNK1,SCG2,SLC17A7,WNK3,C12orf4,RTN4,NLRP3" GO: Biological Process GO:0032940 secretion by cell 4.61E-07 4.52E-03 1.92E-05 1.88E-04 264 1090 "SERPINA3,ABAT,ABR,SYN3,ASIC1,ACHE,ACTN1,ACTN2,ADCY5,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,SYT13,DOC2A,ANK1,PPFIA4,PPFIA2,PPFIA1,APBB1,GPAM,PPFIA3,APP,MADD,CASK,ARNTL,ARRB1,CADPS,PDE8B,ATP2A2,SYNJ1,ARHGEF7,BTK,CACNA1I,CACNA1G,C5,BAIAP3,CDK5R2,IL33,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALM1,HAP1,CAMK2A,CAMK2G,CANX,SYT6,BRSK2,CBLN1,CCK,CCKBR,CD38,DGKI,CACNA2D2,CBARP,CHGA,CHRNA4,RAB3C,CHRNB2,NRXN3,NRXN1,NRXN2,CLU,MAP4K4,RAB26,CNR1,AKAP5,MYRIP,PNKD,CLOCK,CRHBP,CRY2,SLC32A1,SNCAIP,CSF1R,RIMS4,RIMS2,SNPH,RIMS3,SCRN1,C2CD2L,BLOC1S6,SNAP91,DPYSL2,PDCD6IP,DNM1L,EDN1,EDN3,SYT15,RASGRP1,SIDT2,OPTN,EGFR,DMTN,EPHA5,RABEPK,STX2,F5,F8,PRAM1,FER,FGFR1,FGR,VTI1B,SYT3,TRIM16,BRSK1,TVP23A,OGA,GABBR1,TRAF3IP2,ILDR2,GAD1,GAD2,BRPF3,GALR1,SYT17,CPLX2,CPLX1,GCK,ARFIP1,GDF9,GLS,GLUL,KCNMB4,GNAS,GPER1,PCLO,RAPGEF4,GRIK5,NR3C1,GRM2,GRM7,GRM8,IL1RAPL1,HRH3,HMGB1,HMGCR,HTR2A,ICA1,IGF1,RBPJ,SCIN,C2CD4C,JAK2,KCNA2,KCNB1,KCNC2,KCNJ11,KIT,STXBP5,LAMP2,SYTL4,MAOB,SYT9,MEF2C,SCAMP5,SCG3,MYO5A,MYO6,MYT1,NCAM1,NELL2,NEUROD1,NF1,NNAT,NOS1,CLEC9A,NTRK2,NUCB2,OXTR,P2RX7,P2RY1,PAX6,PCSK5,PDE1C,PDE3B,PDPK1,PFKFB2,SERPINE2,PIK3C2A,PIK3CD,PLCD1,PPP3CA,PPP3CB,PRKCB,PRKCZ,SYTL2,PTAFR,PTPRN,PTPRN2,RAB3A,RFX3,LRRK2,LGR4,WLS,STX1B,SMPD3,IL17RB,SCG5,PPP1R9A,MYO18A,SYBU,NLGN1,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC1A7,SLC6A9,RAB3GAP1,NAPB,LGI3,RIMS1,SNAP25,SNCA,SOX11,CLASP2,STX1A,STXBP1,SYT11,ABCC8,VAMP1,PLCB1,SYN1,SYN2,SYT1,SYT4,SYT5,TAC1,TACR1,EXOC7,TCF7L2,CLASP1,TEK,ATP13A2,TF,SIRT1,LEFTY2,TIAM1,TLR4,ZNF384,TRH,STXBP4,TRPM2,CADM1,VGF,LMF1,VSNL1,P2RY12,LAT2,WNT7A,TRIM9,SCG2,SLC17A7,C12orf4,RTN4,NLRP3" GO: Biological Process GO:0019932 second-messenger-mediated signaling 5.06E-07 4.96E-03 2.10E-05 2.05E-04 80 257 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA3,AGT,ANK2,DGKD,ASPH,ATP1A2,ATP2A2,KSR1,BTK,CACNA1D,CALM1,HAP1,CAMK2D,RGN,AKAP6,RIMS2,NOS1AP,HDAC4,DMD,DMPK,DRD1,RCAN1,FIS1,EDN1,EDN3,EDNRB,EGFR,RCAN2,DMTN,EPHA5,NCALD,MRVI1,PTK2B,CAMKK2,JPH4,GCK,TOX3,GNAS,PCLO,RAPGEF4,GRM1,GUCY1A1,GUCY1B1,PTGDR2,HPCA,HTR5A,IGF1,KCNC2,L1CAM,MYO5A,NCAM1,NEUROD1,NEUROD2,NOS1,NTRK2,KSR2,TREM2,PDE2A,PDE3A,PDE3B,PDE4A,PDE4D,PDPK1,PPP3CA,PPP3CB,MAPK7,TMEM100,LRRK2,PPP1R9A,SLC8A1,MGRN1,TPCN2,RASD2,LAT2,JPH3" GO: Biological Process GO:0051129 negative regulation of cellular component organization 5.50E-07 5.40E-03 2.28E-05 2.22E-04 176 680 "ADCY6,ADD1,ADD2,SEMA6A,OGT,SEMA7A,PPFIA1,APC,APOC1,APOC2,SHROOM2,SEMA4G,SPTBN4,ARHGDIA,ARRB2,DACT3,NUMB,ATM,CFLAR,BMP7,CDK5R1,MTMR2,RAB29,LDLRAD4,ARHGEF1,CBFA2T2,ARHGEF2,CDC42,EVI5L,SLIT2,NRXN1,CLU,CLTC,NGEF,HECTD1,MAP4K4,PICK1,BAG4,CRMP1,CLIP3,AATK,FEZ2,FEZ1,CST3,RUBCN,MYADM,SNPH,ARHGAP24,DBN1,DCC,KIAA0319,SACS,NTM,DLG4,DNM2,SHANK1,DNAJB6,SEMA3D,DMTN,SEZ6,EPS8,APC2,CDKL3,EFEMP1,DLC1,RACK1,FGF13,FGFR3,MAD2L2,SEMA6C,EVL,SEMA4D,INPP5K,GFAP,PPARGC1A,EML4,STMN2,CIT,GSN,LINGO1,IRAK3,PACSIN2,HMGB1,IGF1,RBPJ,SCIN,LRRTM1,STMN1,MAG,MAP4,LYPLAL1,MBP,SCAMP5,MID1,DBNL,MT3,MDGA1,NEUROD2,OMG,OPA1,TMOD2,NLGN3,SEMA5B,PLXNB3,PMP22,PACSIN1,FAT3,PPP3CA,PRKCZ,BCAS3,VPS13C,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PEX5,PID1,CEP97,RAP1GAP,RDX,ROBO2,RPS6KA2,MAP6D1,LRRK2,AP1AR,SALL1,SEMA6D,DRAXIN,ATXN2,SGK1,PPP1R9A,FUZ,FHOD3,NLGN1,KDM4D,SIRT2,TET1,SLIT1,SLN,CDK5RAP2,SNCA,KDM4B,KDM3A,SPP1,KDM4C,SPTAN1,SPTB,RAP1GAP2,SPART,PBLD,CLASP2,KANK1,SYT4,SEMA4A,SMG6,CLASP1,SIRT1,TGFBR3,THRA,HEY2,TMOD1,TNR,TTC3,TMEFF2,GORASP1,PLEKHH2,TOM1L2,TRIM9,TFIP11,PMEPA1,RGMA,SEMA3B,ITM2C,GOPC,RTN4" GO: Biological Process GO:0007009 plasma membrane organization 5.68E-07 5.57E-03 2.34E-05 2.29E-04 88 291 "SYS1,ACTN2,ADCY6,GPR158,DPP10,ANK1,ANK2,ANK3,PPFIA1,PRX,SPTBN4,NUMB,ATP1B3,ATP2A2,BBS2,MYRF,CACNB2,KALRN,MAP7,CDH2,NRXN1,CLU,CLTC,HECTD1,RAB26,BAG4,CLIP3,APPL1,MYADM,DNM2,DPP6,TSPAN5,OPTN,SH3GLB1,GOLGA7,MTSS1L,STX2,RACK1,FGF13,BAIAP2,VTI1B,SGIP1,SORBS1,FYB1,RAPGEF6,INPP5K,GPER1,PACSIN2,KCNB1,ZFYVE27,LYPLAL1,MYO5A,P2RX7,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,PIK3R1,PACSIN1,FA2H,PRKCZ,SYTL2,PTCH1,PID1,SH3TC2,FAT4,RDX,KCNIP3,CLIP1,SCP2,KIF13A,SCN3B,TNIK,SPTB,NFASC,CLASP2,EPB41L3,STXBP1,ANO4,CRB1,TSC2,TUB,TMEFF2,WNK3,PLSCR4,GOPC,TTC7A" GO: Biological Process GO:1903779 regulation of cardiac conduction 6.12E-07 6.01E-03 2.51E-05 2.46E-04 30 67 "AGT,ANK2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,CAMK2D,DMPK,ABCC9,AHCYL1,KCNJ11,FXYD7,FXYD6,NOS1,NPPA,NPR2,PDE4D,FXYD1,RYR1,RYR3,SLC8A2,SLC8A1,SLC8A3,TRPC1" GO: Biological Process GO:0051656 establishment of organelle localization 6.18E-07 6.06E-03 2.52E-05 2.47E-04 122 438 "ADORA3,SYT13,DOC2A,AMPH,CDC42BPA,CNIH2,SHROOM2,CADPS,ATM,ATP2A2,BBS2,SYNJ1,BTK,CACNA1A,HAP1,CANX,SYT6,ARHGEF2,CDC42,CHGA,MYRIP,SEC24C,FEZ1,RIMS4,RIMS2,SNPH,RIMS3,DCTN1,CNIH3,BLOC1S6,SEC16A,DNM1,TRAPPC9,DYNC1I1,DNM2,DPYSL2,PDCD6IP,SYT15,RASGRP1,DCTN4,STX2,EYA1,F5,F8,SEC24B,FER,FGF14,FGR,SYT3,DCTN2,SYT17,CPLX2,CPLX1,PSRC1,PCLO,GRIA1,GRIK5,KIF3A,MYLK2,C2CD4C,KIT,SYTL4,MAP4,MAPT,SYT9,BLOC1S2,MYO5A,MYO7A,NEFH,NUMA1,OPA1,OPHN1,P2RX7,PAX6,PDPK1,PIK3CD,GPSM2,PACSIN1,PRKCZ,SYTL2,PTK2,SPDL1,RAB3A,LRRK2,STX1B,AP1AR,ITSN1,SH3GL2,NLGN1,SEC31A,RPH3A,RAB3GAP1,NAPB,SLIT1,CDK5RAP2,RIMS1,SNAP25,SNCA,KIF13A,KIF1B,CLASP2,STX1A,STXBP1,SYT11,SYNE2,SYN1,SYT1,ANKRD28,SYT4,SYT5,CLASP1,SYNE1,UCHL1,GORASP1,LAT2,WNT7A,XPO1,TRIM9,FMN2,SPIRE1,C12orf4,AP3B2" GO: Biological Process GO:1902803 regulation of synaptic vesicle transport 6.53E-07 6.40E-03 2.66E-05 2.60E-04 20 36 "CNIH2,ATP2A2,SYNJ1,RIMS4,RIMS2,RIMS3,DNM1,FGF14,GRIK5,RAB3A,LRRK2,STX1B,NLGN1,RAB3GAP1,NAPB,RIMS1,SNCA,STX1A,STXBP1,SYN1" GO: Biological Process GO:0051932 "synaptic transmission, GABAergic" 6.79E-07 6.66E-03 2.75E-05 2.69E-04 24 48 "SYN3,ADORA1,ADORA2A,CACNA1A,CACNB4,HAP1,CCKBR,CLCN3,CNR1,DBI,DNM1,ERBB4,GABRA1,GABRB3,GABRG2,GRIK1,NF1,OXTR,PLCL1,NLGN1,SLC6A1,STXBP1,TAC1,TACR1" GO: Biological Process GO:0050775 positive regulation of dendrite morphogenesis 7.06E-07 6.93E-03 2.85E-05 2.78E-04 22 42 "ACHE,CAPRIN2,NUMB,KALRN,CAMK2B,NUMBL,AKAP5,DBN1,CDKL3,BAIAP2,STAU2,IL1RAPL1,ITPKA,PAK3,RELN,PTPRD,SGK1,CUX2,OBSL1,TIAM1,BHLHB9,LRP8" GO: Biological Process GO:0006897 endocytosis 7.75E-07 7.60E-03 3.12E-05 3.04E-04 172 665 "ABR,ACHE,ADD1,CDC7,ADORA1,ADORA2A,SNX30,ESYT2,ADRB2,AP2A1,AP2A2,SNX32,PLA2G6,SRPX,AMPH,BIN1,APLP1,DGKD,APOC1,APOC2,APP,ARRB1,ARRB2,ASGR1,MARCH3,SYNJ1,MTMR2,CANX,HIP1R,SCARB1,CD81,CDC42,EPS15L1,ZFYVE9,CLCN3,CLTA,CLTB,CLTC,PICK1,CLIP3,CSNK1E,CSNK1G3,CALY,RUBCN,GAPVD1,SNPH,ZFYVE16,TBC1D5,SIRPA,DNAJC6,ELMO1,MAGI2,SNAP91,DLG4,DNM1,DNM2,DOCK2,DPYSL2,ABI1,TOM1,DNM1L,TNK2,CALCRL,RABEPK,SIRPB1,RACK1,FCGR1A,FCGR1B,FCGR3A,BAIAP2,FGR,SCARA3,MEX3B,ANKFY1,SGIP1,FOLR2,TMEM175,ATP6V1H,HHIPL1,FYN,MEGF10,NCKAP1,DNER,GHR,LOXL3,STON1,GRK4,GRIA1,GRIA2,GSN,KIF3A,PTPN5,HBA1,PACSIN2,NCKAP1L,HMGB1,HNRNPK,HP,HPR,HSP90AA1,SMAP1,IRF8,LRRTM1,ITGAV,LDLRAD3,LRP1B,SCAMP5,DBNL,MSR1,MYO6,MYO7A,CLEC9A,OLR1,OPHN1,P2RX7,TREM2,ENPP2,NLGN3,PIK3C2A,PIK3R1,SNX10,EPN1,LRP12,PACSIN1,SH3KBP1,RAB39A,PRKCG,MAPK3,MASP1,PTK2,PTX3,RAB5B,RAP1GAP,LRRK2,ATXN2,PEAR1,ITSN1,SH3GL2,SH3GL3,NLGN1,EPN2,SLC11A1,ELMO2,ARFGAP1,SNCA,LMBRD1,USP33,FNBP1,FCHO1,MLC1,JMJD6,ARC,SYP,SYT1,SYT5,CNTN2,SYNE1,TF,ICAM5,PARD3,TMPRSS5,TSC2,TUB,UBE3A,VAV1,VAV2,VLDLR,WIPF1,PLPP4,LRP8,WIPF2,PLD4" GO: Biological Process GO:0021885 forebrain cell migration 7.89E-07 7.74E-03 3.15E-05 3.07E-04 31 71 "NRP2,CDK5R1,CDK5R2,ADGRG1,SLIT2,CX3CR1,DRD1,EGFR,EMX2,FGF13,FGFR1,FOXG1,NRG3,DISC1,FUT10,MDGA1,OGDH,MBOAT7,POU3F2,RELN,PEX5,FEZF2,ROBO1,LRRK2,ARX,SLIT1,CNTN2,NR2E1,TNR,LRP8,RTN4" GO: Biological Process GO:0010657 muscle cell apoptotic process 7.89E-07 7.74E-03 3.15E-05 3.07E-04 31 71 "RBM10,AGT,APAF1,ARRB1,ARRB2,BMP7,CAMK2A,CAMK2D,QKI,DMPK,EDN1,ERBB4,PTK2B,APOPT1,HMGCR,HSP90AA1,IGF1,RBPJ,IL12A,JAK2,LIFR,NACA,NFE2L2,PDE1A,PDPK1,PIK3R1,MAPK8,RPS6KA2,DICER1,SIRT1,HEY2" GO: Biological Process GO:0035418 protein localization to synapse 8.24E-07 8.08E-03 3.27E-05 3.20E-04 17 28 "ASIC2,CNIH2,DLGAP1,NRXN1,NRXN2,DLG2,DLG3,DLG4,SHANK1,LRRTM1,KLC1,NLGN3,RELN,NLGN1,WNT7A,ANKS1B,NETO1" GO: Biological Process GO:0006865 amino acid transport 8.58E-07 8.41E-03 3.39E-05 3.31E-04 57 167 "ABAT,ADORA1,ADORA2A,AGT,PPFIA4,PPFIA2,PPFIA1,PPFIA3,SLC7A14,ATP1A2,CACNA1A,CACNB4,CCK,SLC32A1,DPYSL2,SLC43A2,FOLR2,GABBR1,CPLX1,GLS,GRIK1,NR3C1,GRM2,GRM7,HRH3,SLC6A17,KCNJ10,MYO6,NF1,NTRK2,P2RX7,SLC36A4,RAB3A,SLC6A15,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,SLC19A3,TRH,SLC13A3,SLC38A1,SLC17A7,SLC17A6" GO: Biological Process GO:0022029 telencephalon cell migration 9.04E-07 8.86E-03 3.56E-05 3.48E-04 30 68 "NRP2,CDK5R1,CDK5R2,ADGRG1,SLIT2,CX3CR1,DRD1,EGFR,FGF13,FGFR1,FOXG1,NRG3,DISC1,FUT10,MDGA1,OGDH,MBOAT7,POU3F2,RELN,PEX5,FEZF2,ROBO1,LRRK2,ARX,SLIT1,CNTN2,NR2E1,TNR,LRP8,RTN4" GO: Biological Process GO:0008361 regulation of cell size 9.07E-07 8.90E-03 3.56E-05 3.48E-04 65 199 "ADD1,SEMA6A,OGT,SEMA7A,ANXA7,SHTN1,AQP4,AQP6,SEMA4G,ARHGAP5,ATP2B2,CDK5R1,SLIT2,CLCN3,AATK,PLXNA4,IST1,DBN1,DCC,DNM2,DPYSL2,DSCAM,EDN1,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,FGF13,SEMA6C,SEMA4D,DISC1,HSP90AA1,KCNMA1,L1CAM,MAPT,MT3,NRCAM,NTRK3,OMG,P2RX7,SEMA5B,RDX,RET,SEMA6D,DRAXIN,SLC12A2,SLC12A4,SLIT1,WDTC1,SPP1,RAP1GAP2,SPART,CLASP2,SEMA4A,LRRC8A,TNR,TSC1,TSC2,AMOT,VAV1,VAV2,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0010647 positive regulation of cell communication 1.08E-06 1.06E-02 4.20E-05 4.11E-04 384 1684 "ABAT,PLEKHG5,AXIN2,ADORA1,ADORA2A,ADORA3,ADRA1B,ADRB2,KIDINS220,AGT,KIAA1324,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,SPOP,SRPX,ALK,ANK3,SEMA7A,FGD2,MAP4K3,CNTNAP1,APAF1,ALS2,LGR5,MIER1,CDK10,MADD,ARNTL,ARRB1,ARRB2,ASCL1,CAPRIN2,ASPH,CCAR2,DYNLL1,ATM,RIPK1,BID,CFLAR,KSR1,BMP7,BMPR1B,SYNJ1,ARHGEF7,C5,MMD2,CACNA1B,LURAP1,DIRAS1,CALM1,HAP1,CAMK2B,CAMK2D,SPAG9,CCKBR,CD38,NEURL1,DGKI,CD81,CDC42,CDH2,LGI1,CRLF1,GPR37L1,ADGRG1,CHGA,CHN1,CHN2,CHRNB2,TAOK2,NRXN1,CLU,SLC24A2,LY86,AKAP6,AKAP5,MAGED1,BAG4,MYRIP,ZNF385A,SH2B1,AKAP12,CSF1,CSF1R,CSNK1E,CHD5,CTH,PUM1,RIMS2,CX3CR1,NOS1AP,RASSF2,DAPK3,DBI,DBN1,DCC,ZEB2,C2CD2L,GSDME,DLG4,DNM1,CDON,SHANK1,DOCK2,DRD1,DUSP9,DNM1L,FIS1,GOLT1B,TSPAN5,EDN1,EDN3,EDNRA,RASGRP1,EEF1D,SH3GLB1,EGFR,SORBS3,IRAK4,TENM1,DMTN,EPS8,ERBB2,ERBB4,DNAJC27,TLR7,RRAGB,ADGRV1,EYA1,F3,WAC,PTK2B,TAOK3,RACK1,PRMT5,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,SORBS1,ZBED3,APOPT1,TRIM16,NPTN,ATP2C1,OGA,FYN,GAB1,GABBR1,TRAF3IP2,GALR1,NEK6,DISC1,STARD10,GCK,GCNT2,GDF1,MSTN,GDF9,GFAP,GHR,MALT1,COPS8,SPIN1,GLUL,GNAS,GNG3,GPER1,GPR37,RAPGEF4,GRB10,RAPGEF1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,NR3C1,GRM1,GRM5,GSN,RNF165,PTPN5,MAP4K5,PTGDR2,TNFAIP8L3,HMGB1,HMGCR,HNRNPK,HTR2A,IGF1,NKD1,RBPJ,HES5,IL6R,IL6ST,IL12A,LRRTM1,ITGAV,ITPKB,JAK2,KIT,L1CAM,LAMA2,LIMS1,FGFBP3,PIK3AP1,NAT8L,MDFI,KITLG,MID1,DBNL,MT3,RSPO2,NCAM1,NELL2,NEUROD2,NF1,NNAT,NODAL,NOS1,NRGN,NTRK2,NTRK3,KSR2,NUCB2,OXTR,P2RX7,P2RY1,TREM2,PAK3,PAX6,PDGFRA,TMOD2,PFKFB2,NLGN3,SERPINE2,PIK3R1,NLE1,PLXNB1,RC3H2,PRRX1,SEPT4,MED1,PPP3CB,PPP3CC,PPP5C,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,DIRAS2,RELN,KLK6,PSMA6,PSMD13,PTK2,PTN,RAB3A,RASGRF1,RASGRF2,DUSP15,RET,KIF7,RNF220,ROBO1,FBXW7,PRR5L,LRRK2,LGR4,WLS,STX1B,S100B,SALL1,TNFRSF19,SMPD3,SFPQ,SH3BGR,SH3BP2,ITSN1,PPP1R9A,MAGI3,AMBRA1,NLGN1,ANKRD6,CLSTN1,SLA,SLC1A3,LIMS2,SLC8A2,RAB3GAP1,SLC8A3,CDK5RAP3,SHANK2,SMARCA4,IGSF9B,RIMS1,SNAP25,MAPKBP1,SNCA,MBD5,SOX2,TNIK,SOX11,UNC5B,ZNF423,IQSEC2,LMO3,TAB2,CLSTN2,MESP1,STOX1,ST5,MAPK8IP3,STAU1,STX1A,KANK1,SULF2,FGD4,SUPT5H,PLCB1,ARC,SYT1,TAC1,TACR1,MLST8,MCF2L,CNTN2,WWC1,CUX2,TCF7L2,PUM2,CRTC1,TEK,TF,SIRT1,LEFTY2,TGFBR3,THRA,TIAM1,NACC2,TLR4,ZFP91,NR2E1,TNFRSF1B,TNR,PIK3R5,TP53BP2,RASD2,TRH,TRPM2,TRPS1,NTSR2,RUSC1,TSC2,UBC,UBE3A,VSNL1,WNT7A,RICTOR,ZIC2,NDRG4,CRB2,TMEM198,MEIS3,MAP3K12,MFF,ITM2C,NELFE,EPM2A,VANGL2,IFT88,NETO2,NETO1,RNF146" GO: Biological Process GO:0048638 regulation of developmental growth 1.26E-06 1.23E-02 4.89E-05 4.77E-04 99 343 "ADRB2,AGT,SEMA6A,SEMA7A,PI16,GPAM,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,AZGP1,BBS2,CDK5R1,CAPN3,NOG,CACNA2D2,SLIT2,CPNE6,NIPBL,AKAP6,NCOR1,AATK,CSF1,PLXNA4,RIMS2,IST1,DBN1,DCC,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,ERBB4,CDKL3,OLFM1,FGF13,FGFR1,FGFR3,SEMA6C,SEMA4D,SYT3,CELF1,SYT17,DISC1,ATP8A2,MSTN,GHR,GNAS,NR3C1,MAEL,HNRNPK,IGF1,NKD1,RBPJ,KCNK2,L1CAM,MAPT,MEF2C,CPNE9,MT3,MYH6,NACA,NCAM1,NRCAM,NTRK3,OMG,SEMA5B,FTO,POU3F2,PROX1,PTCH1,PTK2,PEX5,SEMA6D,DRAXIN,ATXN2,ARX,SLIT1,RIMS1,MBD5,SOX15,SPP1,SPART,CLASP2,PLCB1,SYT1,SYT4,SEMA4A,WWC1,TCF7L2,TLL2,HEY2,TNR,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0023056 positive regulation of signaling 1.27E-06 1.25E-02 4.92E-05 4.81E-04 379 1662 "ABAT,PLEKHG5,AXIN2,ADORA1,ADORA2A,ADORA3,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,SPOP,SRPX,ALK,SEMA7A,FGD2,MAP4K3,CNTNAP1,APAF1,ALS2,LGR5,MIER1,CDK10,MADD,ARNTL,ARRB1,ARRB2,ASCL1,CAPRIN2,ASPH,CCAR2,DYNLL1,ATM,RIPK1,BID,CFLAR,KSR1,BMP7,BMPR1B,SYNJ1,ARHGEF7,C5,MMD2,CACNA1B,LURAP1,DIRAS1,CALM1,HAP1,CAMK2B,CAMK2D,SPAG9,CCKBR,CD38,NEURL1,DGKI,CD81,CDC42,CDH2,LGI1,CRLF1,GPR37L1,ADGRG1,CHGA,CHN1,CHN2,CHRNB2,TAOK2,NRXN1,CLU,SLC24A2,LY86,AKAP6,AKAP5,MAGED1,BAG4,MYRIP,ZNF385A,SH2B1,AKAP12,CSF1,CSF1R,CSNK1E,CHD5,CTH,PUM1,RIMS2,CX3CR1,NOS1AP,RASSF2,DAPK3,DBI,DBN1,DCC,ZEB2,C2CD2L,GSDME,DLG4,DNM1,CDON,SHANK1,DOCK2,DRD1,DUSP9,DNM1L,FIS1,GOLT1B,TSPAN5,EDN1,EDN3,EDNRA,RASGRP1,EEF1D,SH3GLB1,EGFR,SORBS3,IRAK4,TENM1,DMTN,EPS8,ERBB2,ERBB4,DNAJC27,TLR7,RRAGB,ADGRV1,EYA1,F3,PTK2B,TAOK3,RACK1,PRMT5,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,SORBS1,ZBED3,APOPT1,TRIM16,NPTN,ATP2C1,NSG1,OGA,FYN,GAB1,GABBR1,TRAF3IP2,GALR1,NEK6,DISC1,STARD10,GCK,GCNT2,GDF1,MSTN,GDF9,GFAP,GHR,MALT1,COPS8,SPIN1,GLUL,GNAS,GNG3,GPER1,GPR37,RAPGEF4,GRB10,RAPGEF1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,NR3C1,GRM1,GRM5,GSN,RNF165,PTPN5,BVES,MAP4K5,PTGDR2,TNFAIP8L3,HMGB1,HMGCR,HNRNPK,HTR2A,IGF1,NKD1,RBPJ,HES5,IL6R,IL6ST,IL12A,LRRTM1,ITGAV,ITPKB,JAK2,KIT,L1CAM,LAMA2,LIMS1,FGFBP3,PIK3AP1,NAT8L,MDFI,KITLG,MID1,DBNL,MT3,RSPO2,NCAM1,NELL2,NEUROD2,NF1,NNAT,NODAL,NOS1,NRGN,NTRK2,NTRK3,KSR2,NUCB2,OXTR,P2RX7,P2RY1,TREM2,PAK3,PAX6,PDGFRA,TMOD2,PFKFB2,NLGN3,SERPINE2,PIK3R1,NLE1,PLXNB1,RC3H2,PRRX1,SEPT4,MED1,PPP3CB,PPP3CC,PPP5C,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,DIRAS2,RELN,KLK6,PSMA6,PSMD13,PTK2,PTN,RAB3A,RASGRF1,RASGRF2,DUSP15,RET,KIF7,RNF220,ROBO1,FBXW7,PRR5L,LRRK2,LGR4,WLS,STX1B,S100B,SALL1,TNFRSF19,SMPD3,SFPQ,SH3BGR,SH3BP2,ITSN1,PPP1R9A,MAGI3,NLGN1,ANKRD6,CLSTN1,SLA,SLC1A3,LIMS2,SLC8A2,RAB3GAP1,SLC8A3,CDK5RAP3,SHANK2,SMARCA4,IGSF9B,RIMS1,SNAP25,MAPKBP1,SNCA,MBD5,SOX2,TNIK,SOX11,UNC5B,ZNF423,IQSEC2,LMO3,TAB2,CLSTN2,MESP1,STOX1,ST5,MAPK8IP3,STAU1,STX1A,KANK1,SULF2,FGD4,PLCB1,ARC,SYT1,TAC1,TACR1,MLST8,MCF2L,CNTN2,WWC1,CUX2,TCF7L2,PUM2,CRTC1,TEK,TF,SIRT1,LEFTY2,TGFBR3,THRA,TIAM1,NACC2,TLR4,ZFP91,NR2E1,TNFRSF1B,TNR,PIK3R5,TP53BP2,RASD2,TRH,TRPM2,TRPS1,NTSR2,RUSC1,UBC,UBE3A,VSNL1,WNT7A,RICTOR,ZIC2,NDRG4,CRB2,TMEM198,MEIS3,MAP3K12,MFF,ITM2C,NELFE,VANGL2,IFT88,NETO2,NETO1,RNF146" GO: Biological Process GO:0010959 regulation of metal ion transport 1.38E-06 1.35E-02 5.32E-05 5.20E-04 106 374 "ACTN2,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AGT,PLA2G6,DPP10,ANK2,ANK3,KCNAB2,CASK,SPTBN4,ARRB2,ASPH,ATP1A1,ATP1A2,ATP1B3,ATP2B2,CACNA1G,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,RGN,CBARP,STOML1,CNTN1,AKAP7,AKAP6,AKAP5,NOS1AP,DBI,DMD,DMPK,DNM2,DPP6,DRD1,EDN3,EDNRA,SGK2,PTK2B,FGF12,FGF14,FHL1,SARAF,OGA,CAB39,AHCYL1,JPH4,INPP5K,GCK,GNAO1,GNAS,MCHR1,GPER1,HTR2A,IGF1,KCNC1,KCNC2,KCNH2,KCNN2,MYO5A,NOS1,NPPA,OPRL1,P2RX7,PDE4B,PDE4D,PDPK1,SERPINE2,PIK3C2A,FXYD1,NKAIN4,NKAIN1,KCNIP3,KCNIP2,KCNIP1,SCN2B,SCN4B,SGK1,SLC8A1,SLN,SNCA,SCN3B,NKAIN2,ABCC8,PLCB1,TRPC1,TRPC3,KCNE5,SGK3,BEST1,P2RY12,KCNAB1,WNK3,WNK2,JPH3" GO: Biological Process GO:0016049 cell growth 1.54E-06 1.51E-02 5.93E-05 5.79E-04 148 562 "NDRG3,ADRA1B,AGT,SEMA6A,ALCAM,LTBP4,SEMA7A,PI16,APBB1,APBB2,EPB41L5,DGKD,APP,SHTN1,CPNE5,SEMA4G,CAPRIN2,DACT3,CCAR2,ADAM15,NRP2,CDK5R1,FUBP1,FOXK1,CACNA1A,DDR1,CAMK2D,CD38,CD81,CDK11B,SEPT7,CDC42,DCLK1,LGI1,TAOK2,SLIT2,LHX2,CPNE6,AKAP6,AATK,SOCS5,PLXNA4,CTH,RIMS2,KIF26A,IST1,DBN1,DCC,ZEB2,DNM2,DPYSL2,DSCAM,EDN1,SGK2,SEMA3D,EGFR,PLXNC1,EIF4G2,RASGRP2,ERBB2,CDKL3,CD320,NRN1,ACSL4,PTK2B,RACK1,KIAA1109,OLFM1,FGF13,MAD2L2,FHL1,IP6K2,FOXM1,SEMA6C,SEMA4D,SYT3,PDLIM5,CGREF1,NRG3,SYT17,DISC1,GDF9,KDM2B,GNG4,PSRC1,NR3C1,FAM107A,IGFBPL1,HNRNPK,IFI16,IGF1,IGFBP1,IL6R,ITGAV,L1CAM,MAPT,CPNE9,MT3,N6AMT1,NPPA,NRCAM,NTRK3,OMG,NLGN3,SERPINE2,SEMA5B,PLXNB1,PPP3CB,PRKCZ,PTK2,USP47,SEMA6D,SBF1,DRAXIN,IL17RB,SGK1,CLSTN1,SLIT1,SMARCA4,RIMS1,SPP1,TSPYL2,SPART,CLASP2,EPB41L3,ERBIN,SYT1,COBL,SYT4,SEMA4A,TAF9,SIRT1,LEFTY2,ZMAT3,TGFBR3,TIAM1,TNR,TRO,SGK3,CADM1,FLRT1,ATP6V0E2,NDRG4,RGMA,SEMA3B,HRASLS,RTN4,PAK5" GO: Biological Process GO:0071625 vocalization behavior 1.70E-06 1.66E-02 6.50E-05 6.35E-04 11 14 "NLGN4X,NRXN3,NRXN1,NRXN2,CNTNAP2,DLG4,SHANK1,NLGN3,MYH14,NLGN4Y,SHANK2" GO: Biological Process GO:0086010 membrane depolarization during action potential 1.98E-06 1.94E-02 7.51E-05 7.34E-04 22 44 "ANK2,ANK3,ATP1A2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,KCNH2,NALCN,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A1,SCN3B,TPCN2" GO: Biological Process GO:0070252 actin-mediated cell contraction 1.98E-06 1.94E-02 7.51E-05 7.34E-04 39 102 "ACTN2,ANK2,EPB41L5,SHTN1,ATP1A1,ATP1A2,ATP2A2,CACNA2D1,CACNB2,CAMK2D,MYL6B,AKAP6,NOS1AP,DBN1,DMD,FGF12,MYLK2,KCNH2,CTNNA3,MYBPC1,MYH3,MYH6,MYH7,MYL3,PDE4B,PDE4D,FXYD1,SCN2B,SCN4B,SCN3B,TMOD1,PARD3,TNNT1,TPM1,TPM2,TPM3,TPM4,KCNE5,FRMD6" GO: Biological Process GO:0010243 response to organonitrogen compound 2.01E-06 1.97E-02 7.56E-05 7.39E-04 213 866 "SERPINA3,ABAT,ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1B,ADRB2,AGT,OSBPL8,ALAD,OGT,APLP1,UPRT,GPAM,APP,ASCL1,ASPH,ATP1A2,ATP2A2,ATP6V1G2,ATP6V0A1,BCHE,HCN2,BLM,BMP7,CALM1,KALRN,CAMK2A,CBS,P2RX6,AIFM1,NEURL1,ARHGEF2,CDO1,CHRNA4,CHRNB2,SLIT2,SLC22A6,ABCG2,CNGA3,CNR1,AKAP7,AKAP6,AKAP5,CPS1,CREM,CRHBP,CRY2,APPL1,HDAC9,LYPD1,DLG4,DNM2,CPEB2,DPYSL2,DRD1,EDN1,EDNRA,EGFR,DMTN,RRAGB,PTK2B,PPP1R1B,FER,BAIAP2,FOXM1,FOLR2,SORBS1,TRIM16,ATP6V1H,FYN,GAB1,GABBR1,GABRA1,GABRB1,GABRB3,GABRG2,AHCYL1,INPP5K,GATM,GCK,MSTN,SESN1,GHR,PPARGC1A,GLRB,GNAL,GNAO1,GNAS,GNG3,GNG4,GPD1,GPR22,GPER1,GRB10,RAPGEF1,GRIN1,GSN,PTPN5,IRAK3,HNMT,HNRNPK,HPCA,HTR2A,IGF1,IGFBP1,JAK2,KCNC1,KCNC2,KCNJ11,KCNK1,KHK,IPO5,MAT2A,MBD1,MEF2C,MOG,SESN3,MYO5A,NCAM1,NEFH,VWA2,NOS1,NPPA,HCN1,NTRK2,NUCB2,OGG1,OXTR,P2RX7,TREM2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDE1B,PDGFRA,PDPK1,GPR173,GNG2,PENK,SSH1,PIK3C2A,PIK3R1,PKM,PLCD1,PPARA,PPP3CA,PPP5C,PRKACB,PRKAR1B,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK9,PTAFR,PTK2,PTN,PTPRE,CASTOR1,PTPRN,PYGM,QDPR,PID1,RNASEL,RPE65,LRRK2,RXRA,RYR1,RYR3,SELL,SGK1,CPEB3,SLC1A2,SLC1A3,SLC6A1,SLC8A1,SLC8A3,SIRT2,CPEB4,SNCA,MBD5,LMBRD1,WDTC1,SST,SSTR1,SSTR2,ERBIN,KANK1,ABCC8,PLCB1,TAC1,TACR1,ADGRL3,ZEB1,TEK,SIRT1,ZNF106,TIAM1,TIMP4,STXBP4,TRPC3,TSC1,TSC2,VGF,VLDLR,P2RY12,ATP6V0E2" GO: Biological Process GO:1990138 neuron projection extension 2.01E-06 1.97E-02 7.56E-05 7.39E-04 56 167 "SEMA6A,ALCAM,SEMA7A,SHTN1,CPNE5,SEMA4G,NRP2,CDK5R1,DDR1,DCLK1,SLIT2,LHX2,CPNE6,AATK,PLXNA4,RIMS2,DBN1,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,NRN1,OLFM1,SEMA6C,SEMA4D,SYT3,SYT17,DISC1,HNRNPK,L1CAM,MAPT,CPNE9,MT3,NRCAM,NTRK3,NLGN3,SEMA5B,PLXNB1,PPP3CB,PRKCZ,SEMA6D,DRAXIN,SLIT1,RIMS1,CLASP2,SYT1,SYT4,SEMA4A,TIAM1,TNR,FLRT1,SEMA3B,RTN4" GO: Biological Process GO:0032970 regulation of actin filament-based process 2.01E-06 1.97E-02 7.56E-05 7.39E-04 98 342 "ACTN2,ADD1,ADD2,ANK2,PPFIA1,SHROOM2,SPTBN4,ARHGDIA,ATP1A1,ATP1A2,ATP2A2,CDK5R1,WASF1,CAMK2D,CFL2,SLIT2,PICK1,AKAP6,BAG4,CSF1R,ARHGEF10,NOS1AP,MYADM,DAPK3,DBN1,SHANK1,EDN1,ABI2,SORBS3,TENM1,DMTN,EPHA5,EPS8,PTK2B,DLC1,FER,BAIAP2,FGR,EVL,STAU2,NCKAP1,IQGAP2,INPP5K,ARFIP1,GPM6B,CIT,GSN,NCKAP1L,SYNPO,MYLK2,SCIN,MEF2C,DBNL,CTNNA3,NTRK3,PAK3,PDE4B,PDE4D,PDGFRA,TMOD2,SSH1,PIK3R1,FXYD1,MAGEL2,PROX1,BCAS3,RDX,KIRREL1,AP1AR,PPP1R9A,PPM1E,ASAP3,FHOD3,CCDC88A,SPTAN1,SPTB,CLASP2,KANK1,TAC1,TACR1,MLST8,CLASP1,TEK,TMOD1,PARD3,TPM1,TSC1,TMEFF2,AMOT,PLEKHH2,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B,VANGL2,FRMD6" GO: Biological Process GO:0014003 oligodendrocyte development 2.05E-06 2.01E-02 7.68E-05 7.50E-04 20 38 "ASCL1,MYRF,CLU,TENM4,MED12,ERCC2,FGFR3,NKX6-2,WASF3,GSN,HES5,KCNJ10,NKX2-2,OMG,PLP1,FA2H,SOX11,CNTN2,TCF7L2,PRDM8" GO: Biological Process GO:0021761 limbic system development 2.35E-06 2.31E-02 8.77E-05 8.56E-04 41 110 "NR0B1,NCOA1,BBS2,NRP2,CDK5R1,CDK5R2,HAP1,AKAP5,SLC32A1,CNTNAP2,ZEB2,DLX1,DRD1,EMX2,EPHA5,EZH1,FGF13,FGFR1,TBR1,KIRREL3,DCLK2,KIF3A,HNRNPK,HTR5A,KCNA1,NEFH,NEUROD1,NF1,OGDH,POU3F2,PROX1,RELN,PTPRZ1,FEZF2,ATAT1,BCAN,RAB3GAP1,SOX3,NR2E1,TSC1,LRP8" GO: Biological Process GO:0040011 locomotion 2.94E-06 2.88E-02 1.09E-04 1.07E-03 391 1735 "ABR,ABHD6,PLEKHG5,ADORA1,ADORA2A,UNC5A,ADORA3,MTUS1,AGT,HACE1,OSBPL8,PLA2G6,SEMA6A,ALCAM,MRTFA,CDC42BPA,ANK3,SEMA7A,APBB1,APBB2,APC,EPB41L5,DGKZ,APP,SHTN1,SHROOM2,SEMA4G,SPTBN4,ARHGAP5,ARHGDIA,ARRB2,ASCL1,DNAH17,CHRD,NUMB,ASTN1,ATP1A2,ATP1B3,ATP2B2,ADAM15,BBS2,NRP2,BMP7,BMPR1B,CDK5R1,DST,ARHGEF7,CACNA1I,C5,CDK5R2,IL33,LDLRAD4,CACNA1E,DDR1,LURAP1,CAMK2D,ISPD,SPAG9,CCK,LDB2,KRIT1,FMNL3,RGN,CD86,SCARB1,NEURL1,CD81,CDC42,CDH2,DCLK1,LGI1,NOG,ADGRG1,CHGA,CHN1,CHRM1,CHRM4,JAM2,TAOK2,SLIT2,LHX2,NRXN3,NRXN1,BAG4,NRG2,HS3ST5,CDC42BPB,CRMP1,CSF1,CSF1R,CSF3R,FEZ2,FEZ1,VCAN,PLXNA4,SDC3,CMTM5,CX3CR1,BOC,DOCK4,HDAC9,MYADM,TCAF1,ARHGAP24,HDAC4,KIF26A,DAPK3,SIRPA,DBN1,DCC,ZEB2,ELMO1,KIAA0319,MAGI2,SRGAP3,DOCK2,DPYSL2,DRD1,DSCAM,RCAN1,WDPCP,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,ABI2,EGR3,PLXNC1,IRAK4,TNK2,EMX2,PLEKHO1,RCAN2,DMTN,EPHA5,EPHB1,EPS8,ERBB2,ERBB4,APC2,ETV1,CEND1,F3,PTK2B,TUBB3,EFEMP1,DLC1,ATP8A1,RACK1,FKTN,FER,FGF1,OLFM1,FGF13,FGFR1,FGR,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,DPYSL4,TBR1,NRG3,FYN,GAB1,CHL1,NCKAP1,GAP43,DISC1,DNER,GBX2,GCNT2,GFRA1,PPARGC1A,KIRREL3,GLI2,GPM6A,FUT10,GPER1,GPR37,RAPGEF4,RFFL,GRIN2C,GRM5,GSN,RNF165,BVES,RABL2A,ATOH8,CELF3,HAS2,PADI2,PTGDR2,NCKAP1L,HMGB1,HSP90AA1,HTR2A,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INPP5B,INSM1,TUBB2B,ITGA7,ITGAM,ITGAV,JAK1,JAK2,KIF5A,KIF5C,KIT,L1CAM,LAMA2,PAXBP1,MAG,MAPT,MARK1,MATK,MATN2,MEF2C,KITLG,MITF,MOG,CCDC80,MDGA1,MYO5A,NACA,NBL1,NCAM1,NF1,NFE2L2,NODAL,NRCAM,NRDC,NTRK2,NTRK3,DDR2,OGDH,OLR1,OPHN1,P2RY1,PAK3,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,ANLN,PIK3CD,PIK3R1,PLTP,PLXNB1,PLXNB3,SCHIP1,MBOAT7,EPB41L4B,FAT3,SH3KBP1,POU3F2,PPP3CB,PKN2,PRKCZ,MAPK3,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PTX3,PEX2,PEX5,CCDC40,FEZF2,RDX,RET,RFX3,ROBO1,ROBO2,FBXW7,PRR5L,LRRK2,SOX8,AP1AR,SEMA6D,DRAXIN,SELL,SGK1,ARX,FERMT1,ASAP3,MYO18A,DOCK10,FUZ,ST6GAL1,SLC8A1,CCDC88A,ELMO2,SLC20A2,SLIT1,SMARCA4,SNCA,PALLD,USP33,SOX1,SOX10,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,NFASC,PBLD,CLASP2,MESP1,SST,MAPK8IP3,KANK1,SYNE2,PLCB1,ARC,TAC1,TACR1,SEMA4A,ROBO3,EXOC7,UNC5D,CNTN2,ADGRL3,WWC1,SATB2,CLASP1,TEK,TF,DNAH7,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,PARD3,TNR,TNS1,RBFOX2,TPM1,ELP5,TSC2,TMEFF2,SGK3,AMOT,FLRT2,VAV1,VAV2,P2RY12,WNT7A,ZIC2,NDRG4,DPYSL5,ZFAND5,LRP8,SCG2,SEMA3B,FZD3,DOCK8,RTN4,PAK5,VANGL2,SPATA13,JPH3" GO: Biological Process GO:0046058 cAMP metabolic process 3.01E-06 2.95E-02 1.11E-04 1.09E-03 54 161 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,APLP1,PDE8B,CACNB4,CALM1,CHGA,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,RACK1,CAP2,GABBR1,GALR1,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A1,GUCY1B1,HRH3,HPCA,P2RY13,NF1,NUCB2,OPRL1,PALM,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7,PTHLH,MRAP2,GPR161,VIPR2" GO: Biological Process GO:1902531 regulation of intracellular signal transduction 3.18E-06 3.12E-02 1.17E-04 1.15E-03 400 1781 "RALGAPA1,ABR,NDRG2,PLEKHG5,ADORA1,ADORA3,ADRA1B,ADRB2,KIDINS220,AGT,NME5,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,SPOP,ARHGAP20,ALK,OGT,CDC42BPA,SEMA7A,FGD2,MAP4K3,APC,DGKZ,ALS2,LRRC4C,MIER1,CDK10,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARNTL,ARRB1,ARRB2,ASPH,CCAR2,ATM,RIPK1,BARD1,BCL2L2,FGF17,BID,BLM,CFLAR,KSR1,BMP7,CDK5R1,ARHGEF7,C5,MMD2,BTRC,LURAP1,DIRAS1,CALM1,KALRN,HAP1,CAMK2D,CAPN3,SPAG9,ARHGEF25,CBS,RGN,CD86,ARHGEF1,DGKI,CD81,ARHGEF2,CDC42,CDH2,ARHGAP33,CRLF1,GPR37L1,ADGRG1,SOCS6,CHN1,CHN2,TAOK2,ARHGAP22,SLIT2,CLU,NGEF,MAP4K4,ARHGEF6,AKAP7,AKAP6,AKAP5,MAGED1,BAG4,NRG2,ZNF385A,AKAP12,NCOR1,CSF1,CSF1R,ARHGEF10,SIPA1L1,CHD5,SOCS5,PPP1R16B,CTH,ARHGEF4,PUM1,NOS1AP,MYADM,ARHGAP32,ARHGAP24,RASSF2,DCC,ZEB2,TIAM2,MAGI2,GSDME,RHOBTB1,SRGAP3,G3BP2,DMD,CDON,DNM2,DOCK2,RCAN1,DUSP9,DYRK1A,DNM1L,FIS1,GOLT1B,SEZ6L2,EDN1,EDN3,EDNRA,HIPK3,RASGRP1,EEF1D,OPTN,SH3GLB1,FAM13A,EGFR,RASA4,SORBS3,IRAK4,TENM1,PLEKHA1,RCAN2,SEZ6,EPHB1,ERBB2,ERBB4,DNAJC27,TLR7,RRAGB,ADGRV1,F3,PTK2B,TAOK3,DLC1,RACK1,FKTN,PRMT5,FGF1,FGFR1,FGFR3,FGR,PRKAG2,AGAP2,FOXM1,SEMA4D,FLT1,PSD2,AKAP3,STAMBP,NPTN,ATP2C1,DOT1L,FYN,GAB1,TRAF3IP2,ZMYND11,JPH4,ZNF274,NEK6,INPP5K,GCNT2,GDF1,MSTN,GDF9,SESN1,GFRA2,GHR,MALT1,COPS8,GNAS,GNG3,GPER1,GPR37,RAPGEF1,C1QL4,RFFL,GRIK2,GRM1,GRM5,PTPN5,MAP4K5,IRAK3,ARHGAP19,TNFAIP8L3,ARHGAP36,HMGB1,HMGCR,HNRNPK,HTR2A,MYLK2,IGF1,HES5,IL6R,IL6ST,IL12A,INPP5B,LRRTM3,LRRTM1,ITGAV,ITPKB,JAK2,KIT,L1CAM,LRRC4B,FGFBP3,ARHGAP12,PIK3AP1,MDFI,MDM4,KITLG,MID1,DBNL,SESN3,MT3,MYO5A,MYO9A,NCAM1,NEUROD1,NEUROD2,NF1,NFE2L2,NODAL,NOS1,NTRK2,NTRK3,KSR2,OCRL,OPA1,OPHN1,P2RX7,P2RY1,TREM2,PAK3,PDE3B,PDE4A,PDE4D,PDGFRA,PDPK1,DUSP26,SERPINE2,PIK3CD,PIK3R1,PLXNB1,MAPKAP1,RC3H2,SEPT4,PPM1B,PPP2R5C,PPP5C,PRKAB2,PRKCB,PRKCZ,MAPK3,MAPK7,MAPK9,MAPK10,DIRAS2,RELN,PSD,PTK2,PTPN13,CASTOR1,USP47,RAD17,IQSEC3,RAP1GAP,RASGRF1,RASGRF2,RBBP8,RDX,DUSP15,RET,RGS3,RGS4,ARHGEF10L,ROBO1,ELP2,TMEM100,FBXW7,PRR5L,LRRK2,WLS,RMI1,S100B,LRRTM4,FNIP1,TNFRSF19,SMPD3,SEC14L1,SFPQ,RASA3,ITSN1,MAGI3,NLGN1,ANKRD6,PREX2,ARHGEF40,CDK5RAP3,TRIM67,SPHKAP,MAPKBP1,LMBRD1,SOX2,TNIK,SOX11,UNC5B,ARHGAP26,IQSEC2,MCF2L2,RAP1GAP2,LMO3,TAB2,STOX1,LRRC4,ERBIN,ST5,MAPK8IP3,KANK1,FGD4,ARHGEF9,PLCB1,TAF6,MLST8,MCF2L,TAF9,DNMBP,WWC1,FBXW11,MGRN1,TCF7L2,PSD3,ARHGEF12,PUM2,ARHGAP9,TEK,TF,SIRT1,LEFTY2,TIAM1,NACC2,TLR4,ZFP91,TNFRSF1B,PIK3R5,TP53BP2,SEZ6L,RASD2,TRIO,NTSR2,TSC1,TSC2,UBC,UBE3A,AMOT,UCHL1,PDIA2,FLRT2,FLRT1,VAV1,VAV2,MEAF6,WNT7A,WRN,RICTOR,NDRG4,MEIS3,MAP3K12,PCBP4,WNK2,NELFE,EPM2A,KAT6A,NLRP3,VANGL2,SOCS4,SPATA13,JPH3" GO: Biological Process GO:0048640 negative regulation of developmental growth 3.46E-06 3.39E-02 1.27E-04 1.24E-03 39 104 "ADRB2,SEMA6A,SEMA7A,PI16,SEMA4G,BBS2,CDK5R1,NOG,SLIT2,AATK,DCC,SEMA3D,CDKL3,FGF13,FGFR3,SEMA6C,SEMA4D,MSTN,GNAS,NKD1,KCNK2,MT3,SEMA5B,PTCH1,PTK2,SEMA6D,DRAXIN,ATXN2,SLIT1,SPP1,SPART,SEMA4A,WWC1,TCF7L2,TLL2,TNR,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0070997 neuron death 3.50E-06 3.44E-02 1.28E-04 1.25E-03 98 346 "ACHE,ADORA2A,AGT,APAF1,APP,ASCL1,ATM,BID,CDK5R1,NAE1,CACNA1A,AIFM1,CDC42,MAGI1,CRLF1,CHGA,CLU,CNTFR,SLC25A27,AATK,HDAC4,DCC,DLX1,ATN1,OPTN,EN2,EPHB1,PTK2B,RACK1,FGFR3,AGAP2,FOXO3,DPYSL4,STAMBP,FYN,GABRA5,CHL1,GABRB3,ZNF274,GFER,GHR,PPARGC1A,GPR75,TOX3,KDM2B,GRIK2,GRIK5,GRIN1,NR3C1,GRM7,PTPN5,IGF1,JAK2,KCNB1,KCNMA1,LIG4,MEF2C,NRBP2,MT3,NCF2,NF1,NOS1,NTRK2,PAK3,PDPK1,RETREG1,PPARA,PPP2R2B,PPP5C,VSTM2L,PRKCG,MAPK8,KLK6,PTPRZ1,OXR1,FBXW7,LRRK2,KCNIP3,DRAXIN,SCN2A,ITSN1,AMBRA1,CPEB4,SNCB,SNCA,FAIM2,UNC5B,SRPK2,STXBP1,TRIM2,ATP13A2,SIRT1,BHLHB9,TP53BP2,TRPM2,TSC1,XRCC4,MAP3K12" GO: Biological Process GO:0060563 neuroepithelial cell differentiation 4.16E-06 4.08E-02 1.52E-04 1.48E-03 35 90 "ASCL1,ATP2B2,CDH2,SLC4A7,ZEB2,BLOC1S6,USH1C,WDPCP,EDN3,EDNRB,SEC24B,FGFR1,RBPJ,HES5,INSM1,KCNMA1,KIT,MEF2C,KITLG,MITF,AFDN,MYCN,MYO5A,MYO6,MYO7A,NODAL,STRC,TMEM231,SOX10,SOX11,HEY1,HEY2,ADAMTS9,HPS4,PCDH15" GO: Biological Process GO:0006820 anion transport 4.40E-06 4.32E-02 1.60E-04 1.56E-03 163 641 "TTYH1,ABAT,SLC12A5,ADORA1,ADORA2A,AGT,OSBPL8,PLA2G6,ABCD2,PPFIA4,PPFIA2,PPFIA1,APOC1,APOC2,PPFIA3,AQP6,SLC7A14,NCOA1,ATP1A2,SLC4A4,RIPK1,CA4,CA12,CACNA1A,CACNB4,CCK,SLC16A4,SCARB1,ASIC3,CHRNA4,CHRNB2,SLC22A6,CLCN3,CLCN4,CNR1,SLC4A7,SLC4A8,CRY2,SLC32A1,NCOR1,ABCG1,PITPNM3,PNPLA8,TCAF1,PITPNC1,SLC12A6,DPYSL2,DRD1,ABCC5,ABCC9,EDN1,MFSD10,SLC43A2,ACSL4,ATP8A1,FGFR1,PRKAG2,IP6K2,PCYOX1,SLC37A3,FOLR2,PRELID3A,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,AHCYL1,ATP8A2,STARD10,CPLX1,GLRB,GLS,GPM6B,GRIK1,ADAMTS8,NR3C1,GRM2,GRM7,MFSD2A,HBA1,HRH3,TNFAIP8L3,HTR2A,SLC6A17,KCNA2,KCNJ10,TTYH2,SFXN5,NAT8L,MAOB,MTTP,MYO6,NF1,SLCO1C1,NOS1,NTRK2,P2RX7,SLC10A4,BEST3,FXYD1,SLC36A4,PPARA,PRKAB2,PRKCB,MAPK9,SLC26A11,SLC22A23,PTAFR,RAB3A,SLC6A15,ATP8B4,RXRA,SCP2,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLCO1A2,SLC22A4,RIMS1,SNAP25,SNCA,ATP10B,STX1A,STXBP1,ABCC8,SYT1,SLC37A2,ATP11A,ANO4,ACSL6,SLC19A3,SPX,LRRC8A,TRH,CA14,ANO5,PITPNB,BEST1,SLC13A3,SLC26A10,SLC38A1,SLC17A7,SLC17A6,RTN4,SLC4A10" GO: Biological Process GO:0010256 endomembrane system organization 5.12E-06 5.02E-02 1.85E-04 1.81E-03 149 578 "SYS1,ACTN2,ADCY6,GPR158,HACE1,OSBPL8,DPP10,ANK1,ANK2,ANK3,PPFIA1,ALS2,SHTN1,PRX,SPTBN4,NUMB,ATP1B3,STX16,ATP2A2,BBS2,SYNJ1,ARHGEF7,RAB29,MYRF,CACNB2,KALRN,MAP7,CDC42,CDH2,CLCN3,NRXN1,COG1,CLU,CLTC,HECTD1,RAB26,TBPL1,BAG4,ZNF385A,CLIP3,APPL1,UBXN2A,USP6NL,MYADM,IST1,TMEM170A,POM121,SEC16A,DNM1,DMPK,DNM2,DPP6,PDCD6IP,TSPAN5,ATL1,OPTN,SH3GLB1,GOLGA7,MTSS1L,STX2,RTN3,REEP2,RACK1,PRMT5,FGF13,BAIAP2,VTI1B,SGIP1,SORBS1,FYB1,RAPGEF6,NEK6,INPP5K,RAB30,GOLGB1,GPER1,CIT,PACSIN2,AGFG1,TJAP1,KCNB1,KIFC3,ZFYVE27,LYPLAL1,AQP11,BLOC1S2,MYO5A,P2RX7,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,SERPINE2,PIK3R1,SNX10,PACSIN1,FA2H,PRKCB,PRKCZ,MAPK3,BCAS3,SYTL2,PTCH1,PEX5,RAB5B,PID1,SH3TC2,FAT4,RDX,RFX2,ATP8B4,LRRK2,KCNIP3,CLIP1,SCP2,MYO18A,RAB3GAP1,KIF13A,SCN3B,TNIK,SPTB,NFASC,CLASP2,EPB41L3,STXBP1,NSFL1C,SYNE2,SYP,ANO4,WASHC4,CLASP1,SYNE1,OBSL1,CRB1,AKTIP,TSC2,TUB,TMEFF2,GORASP1,REEP1,WNK3,PLSCR4,PARP11,GOPC,RTN4,NUP214,TTC7A,AAAS" GO: Biological Process GO:0097090 presynaptic membrane organization 5.29E-06 5.19E-02 1.91E-04 1.86E-03 11 15 "NLGN4X,CDH2,NRXN1,MAGI2,PCDH17,IL1RAPL1,NLGN3,PTPRD,LRRTM4,NLGN1,CNTN2" GO: Biological Process GO:0008360 regulation of cell shape 5.47E-06 5.36E-02 1.96E-04 1.92E-03 50 148 "CDC7,ERMN,FGD2,ANXA7,GAS7,ARHGDIA,CFAP410,FMNL3,SEPT7,TAOK2,CSF1R,CSNK1E,CSNK1G3,DAPK3,WDPCP,PLEKHO1,EPB41,EPB41L2,DMTN,EPS8,PTK2B,DLC1,BAIAP2,FGR,SEMA4D,FYN,WASF3,TTBK1,FERMT2,KIF3A,BVES,ITGA7,KIT,MKLN1,PALM,PLXNB1,PLXNB3,SH3KBP1,PTK2,PTN,RDX,MYH14,S100B,EPB41L3,TTBK2,FGD4,SEMA4A,TPM1,WIPF1,WIPF2" GO: Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity 5.98E-06 5.86E-02 2.14E-04 2.09E-03 18 34 "AGT,CAMK2B,NEURL1,DLG4,DRD1,NPTN,GRIK1,GRIK2,GRIN1,GRM5,KCNJ10,KIT,NF1,S100B,RIMS1,SNCA,SYP,NETO1" GO: Biological Process GO:0006935 chemotaxis 6.01E-06 5.89E-02 2.14E-04 2.09E-03 148 575 "PLEKHG5,UNC5A,MTUS1,PLA2G6,SEMA6A,ALCAM,ANK3,SEMA7A,APBB1,APBB2,APP,SEMA4G,SPTBN4,ARRB2,NRP2,BMP7,BMPR1B,CDK5R1,C5,ISPD,LGI1,NOG,CHGA,CHN1,SLIT2,LHX2,NRXN3,NRXN1,CRMP1,CSF1,CSF1R,CSF3R,FEZ2,FEZ1,PLXNA4,CMTM5,CX3CR1,BOC,DOCK4,KIF26A,DCC,DOCK2,DPYSL2,DSCAM,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGR3,PLXNC1,EPHA5,EPHB1,ERBB2,ETV1,F3,PTK2B,TUBB3,FER,FGF1,FGFR1,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,DPYSL4,TBR1,NRG3,FYN,CHL1,GAP43,GBX2,GLI2,RNF165,PADI2,PTGDR2,NCKAP1L,HMGB1,IL6R,IL12A,ITGAM,ITGAV,KIF5A,KIF5C,KIT,L1CAM,LAMA2,MATN2,NBL1,NCAM1,NRCAM,NTRK3,OPHN1,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,SEMA5B,PIK3CD,PLXNB1,PLXNB3,MAPK3,RELN,PTAFR,PTK2,PTPRO,FEZF2,ROBO1,ROBO2,SEMA6D,DRAXIN,SELL,ARX,ST6GAL1,ELMO2,SLIT1,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,NFASC,MAPK8IP3,SEMA4A,ROBO3,UNC5D,CNTN2,THBS4,TIAM1,TNR,TSC2,AMOT,FLRT2,VAV1,ZIC2,DPYSL5,SCG2,SEMA3B,FZD3,VANGL2" GO: Biological Process GO:0048857 neural nucleus development 6.36E-06 6.24E-02 2.26E-04 2.21E-03 29 70 "NDRG2,ASCL1,DYNLL1,CDK5R1,CDK5R2,CACNA1A,CALM1,INA,SYNGR3,CDC42,CHRNB2,SLC4A7,SEC16A,SEC24B,FGFR3,KIRREL3,TTBK1,PADI2,KCNC1,KCNC2,MAG,MAOB,MBP,PLP1,MAPKAP1,ARX,ZNF430,SIRT2,CCDC14" GO: Biological Process GO:0007265 Ras protein signal transduction 6.39E-06 6.27E-02 2.26E-04 2.21E-03 94 333 "ABR,PLEKHG5,BRAP,ADRA1B,HACE1,OGT,FGD2,USP28,DGKZ,ALS2,SHTN1,MADD,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,KSR1,ARHGEF7,WASF1,MMD2,KALRN,CAMK2D,ARHGEF25,ARHGEF1,DGKI,ARHGEF2,CDH2,ADGRG1,NGEF,ARHGEF6,AATK,CSF1,ARHGEF10,ARHGEF4,ARHGAP32,ARHGAP24,ELMO1,TIAM2,G3BP2,DNM2,DOCK2,EDNRA,RASGRP1,ABI2,RASA4,RASGRP2,EPS8,ERBB2,DLC1,BAIAP2,FOXM1,PSD2,STAMBP,RAPGEF6,NCKAP1,RAPGEF1,IGF1,ITPKB,SHC3,KITLG,DBNL,NF1,MAPKAP1,PSD,RALGDS,IQSEC3,RASGRF1,RASGRF2,RDX,ARHGEF10L,ROBO1,RTKN,MRAS,RASA3,ITSN1,PREX2,ARHGEF40,TRIM67,IQSEC2,MCF2L2,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,PSD3,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,HRASLS,VANGL2,SPATA13" GO: Biological Process GO:0016482 cytosolic transport 6.68E-06 6.55E-02 2.36E-04 2.30E-03 179 720 "SYS1,ADCYAP1R1,AXIN2,AP2A1,TBC1D14,C1QTNF3,SYT13,DOC2A,AMPH,ANK2,CNIH2,RGS20,CADPS,ASPH,DACT3,ATP1A2,STX16,ATP2A2,BARD1,BMP7,SYNJ1,MTMR2,RAB29,CACNA1A,CALM1,HAP1,CAMK2D,CANX,CAPN3,SYT6,BRSK2,SPAG9,AP4M1,CLTC,AKAP6,CABP1,AKAP5,BAG4,RIMS4,RIMS2,SNPH,TBC1D5,RIMS3,DBI,DCTN1,BLOC1S6,SGSM2,G3BP2,DMD,DNM1,DNM2,DPYSL2,DRD1,EDNRA,SYT15,SH3GLB1,EGFR,STX2,RAB9B,ERBB4,APC2,DNAJC27,TLR7,PTK2B,RACK1,SEC24B,FGF14,VTI1B,ANKFY1,SYT3,ZBED3,PRELID3A,OGA,DENND2A,JPH4,SYT17,CPLX2,CPLX1,WASHC2A,OS9,GPR26,GPER1,PCLO,GRIK5,PTPN5,HNMT,HSPA1L,HSP90AA1,MYLK2,RAB41,IGF1,C2CD4C,JAK2,KCNN3,IPO5,SYTL4,LYPLAL1,SYT9,MDFI,BLOC1S2,MXI1,MYBPC1,MYO5A,NF1,NODAL,NOS1,OGG1,OPHN1,P2RX7,PDE2A,PDE4D,PDPK1,ZDHHC8,PIK3R1,PKD1,MAGEL2,PACSIN1,MED1,PPM1B,PPP3CA,PPP3CB,RANBP3L,PKIA,MAPK3,MAPK7,VPS13C,SYTL2,RAB3A,RDX,FBXW7,LRRK2,STX1B,AP1AR,ELMOD1,ITSN1,SH3GL2,KIF16B,NLGN1,ABLIM3,RPH3A,SLC8A1,RAB3GAP1,NAPB,RIMS1,SNAP25,SNCA,ERC1,PBLD,STX1A,KANK1,SULF2,STXBP1,SYT11,VPS13A,SYN1,SYT1,SYT4,SYT5,FBXW11,TCF7L2,TEK,SIRT1,AKTIP,THRA,TLR4,TRPC1,TRPC3,WIPF1,WNT7A,XPO1,ZIC1,TRIM9,EVI5,HPS4,GOPC,NLRP3,AAAS,AP3B2,JPH3" GO: Biological Process GO:0002028 regulation of sodium ion transport 6.72E-06 6.59E-02 2.36E-04 2.31E-03 34 88 "ADRB2,AGT,ANK3,SPTBN4,ATP1A1,ATP1A2,ATP1B3,CAMK2D,STOML1,CNTN1,DMD,DMPK,DNM2,SGK2,FGF12,FGF14,AHCYL1,GNAS,NOS1,P2RX7,SERPINE2,FXYD1,NKAIN4,NKAIN1,SCN2B,SCN4B,SGK1,SLC8A1,SCN3B,NKAIN2,PLCB1,SGK3,WNK3,WNK2" GO: Biological Process GO:0045161 neuronal ion channel clustering 7.29E-06 7.15E-02 2.56E-04 2.50E-03 10 13 "SPTBN4,PICK1,CNTNAP2,DLG2,NRCAM,GLDN,KCNIP2,NFASC,CNTN2,MTCH1" GO: Biological Process GO:0042330 taxis 7.34E-06 7.20E-02 2.56E-04 2.50E-03 148 577 "PLEKHG5,UNC5A,MTUS1,PLA2G6,SEMA6A,ALCAM,ANK3,SEMA7A,APBB1,APBB2,APP,SEMA4G,SPTBN4,ARRB2,NRP2,BMP7,BMPR1B,CDK5R1,C5,ISPD,LGI1,NOG,CHGA,CHN1,SLIT2,LHX2,NRXN3,NRXN1,CRMP1,CSF1,CSF1R,CSF3R,FEZ2,FEZ1,PLXNA4,CMTM5,CX3CR1,BOC,DOCK4,KIF26A,DCC,DOCK2,DPYSL2,DSCAM,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,EFNA2,EFNA3,EFNB3,CELSR3,EGR3,PLXNC1,EPHA5,EPHB1,ERBB2,ETV1,F3,PTK2B,TUBB3,FER,FGF1,FGFR1,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,DPYSL4,TBR1,NRG3,FYN,CHL1,GAP43,GBX2,GLI2,RNF165,PADI2,PTGDR2,NCKAP1L,HMGB1,IL6R,IL12A,ITGAM,ITGAV,KIF5A,KIF5C,KIT,L1CAM,LAMA2,MATN2,NBL1,NCAM1,NRCAM,NTRK3,OPHN1,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,SEMA5B,PIK3CD,PLXNB1,PLXNB3,MAPK3,RELN,PTAFR,PTK2,PTPRO,FEZF2,ROBO1,ROBO2,SEMA6D,DRAXIN,SELL,ARX,ST6GAL1,ELMO2,SLIT1,USP33,MYCBP2,SPP1,UNC5B,SPTAN1,SPTB,NFASC,MAPK8IP3,SEMA4A,ROBO3,UNC5D,CNTN2,THBS4,TIAM1,TNR,TSC2,AMOT,FLRT2,VAV1,ZIC2,DPYSL5,SCG2,SEMA3B,FZD3,VANGL2" GO: Biological Process GO:0019220 regulation of phosphate metabolic process 7.44E-06 7.29E-02 2.58E-04 2.52E-03 392 1756 "NDRG2,ADAR,ELFN2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,ADGRF5,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,APC,APLP1,ALS2,APOC1,APOC2,LRRC4C,APP,SLC7A14,CDK10,PPP4R4,MADD,SPTBN4,ZFYVE28,ARRB1,ARRB2,CAPRIN2,DYNLL1,ATM,EIF4G3,RIPK1,BARD1,BLM,KSR1,BMP7,CDK5R1,C5,CDK5R2,LDLRAD4,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CBS,CCK,LDB2,CCKBR,CCNH,CCNT1,RGN,SCARB1,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,NOG,CRLF1,GPR37L1,CHGA,SOCS6,TAOK2,SLIT2,CLU,FBXO7,MAP4K4,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,AKAP12,CRY2,NCOR1,CLIP3,CSF1,CSF1R,VCAN,SOCS5,PPP1R16B,CTNND1,PPP6R2,RUBCN,MYADM,HDAC4,RASSF2,DCC,ZEB2,MAGI2,SMG7,PARD6A,DLG2,DLG3,DMD,CDON,DRD1,ABI1,DSCAM,RCAN1,DUSP9,DNM1L,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,HIPK3,RASGRP1,SH3GLB1,CELSR3,EGFR,SORBS3,TENM1,TNK2,CALCRL,DMTN,EPHB1,ERBB2,ERBB4,DNAJC27,TLR7,PTK2B,TAOK3,DLC1,RACK1,FKTN,STRADA,PRMT5,PPP1R1B,FECH,FER,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,CAP2,AGAP2,RGPD5,FOXM1,SEMA4D,FLT1,ZBED3,NPTN,CAMKK2,NRG3,FYN,GAB1,GABBR1,CAB39,ZMYND11,GALR1,ZNF274,INPP5K,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,PCDH11X,GNAL,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,C1QL4,GRIK2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,GUCY1A2,GUCY1A1,MAP4K5,IRAK3,HRH3,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HPCA,HTR2A,MYLK2,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,INSM1,LRRTM3,LRRTM1,ITGAV,ITPKB,JAK2,KIT,LRRC4B,CAMK2N2,FGFBP3,PIK3AP1,MDFI,MEF2C,KITLG,MID1,DBNL,MT3,P2RY13,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,NUCB2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PALM,PAX6,PC,PDE2A,PDE4D,PDGFRA,ENPP2,PDPK1,PFKFB2,PGAM2,DUSP26,PIK3R1,PKD1,PLCD1,PLCL1,SLC25A23,PPARA,PPP1R1A,PPP2R2B,PPP2R2C,LRRN3,PTPA,PPP2R5C,PPP2R5E,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCZ,MAPK3,MAPK7,MAPK9,MAPK10,DIRAS2,PROX1,RELN,SYTL2,PTAFR,PTHLH,PTH1R,PTK2,PTPRZ1,PPP2R3C,PID1,RAD17,DUSP15,RET,RGS3,RGS4,KIRREL1,MRAP2,FBXW7,PRR5L,LRRK2,CSRNP3,ATXN1,ATXN7,LRRTM4,FNIP1,TNFRSF19,ITSN1,PPP1R9A,PPM1E,MAGI3,AMBRA1,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,TMEM132D,MAPKBP1,SNCA,LMBRD1,SOX2,TNIK,DBNDD2,TSPYL2,RBM26,LMO3,TAB2,PBLD,STOX1,SAMSN1,LRRC4,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,SMG6,NSD1,TEK,TF,DICER1,SIRT1,LEFTY2,GPR161,AKTIP,THBS4,TIAM1,TLR4,ZFP91,RIMBP2,TNFRSF1B,PARD3,PIK3R5,IL34,NTSR2,TSC1,TSC2,UBC,UCHL1,FLRT2,FLRT1,VAV2,VIPR2,MICAL1,VLDLR,WNT7A,RICTOR,ELFN1,NDRG4,WNK1,PMEPA1,MAP3K12,LRP8,RGMA,WNK3,WNK2,NELFE,VANGL2,SOCS4" GO: Biological Process GO:1990778 protein localization to cell periphery 7.45E-06 7.30E-02 2.58E-04 2.52E-03 69 227 "SYS1,ACTN2,ADCY6,GPR158,DPP10,ANK1,ANK2,ANK3,PPFIA1,SPTBN4,NUMB,ATP1B3,BBS2,CACNB2,KALRN,MAP7,CDH2,NRXN1,CLTC,HECTD1,RAB26,BAG4,CLIP3,APPL1,MYADM,DPP6,TSPAN5,OPTN,GOLGA7,RACK1,FGF13,MEX3B,VTI1B,SORBS1,FYB1,RAPGEF6,INPP5K,GPER1,KCNB1,ZFYVE27,LYPLAL1,MYO5A,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,PIK3R1,PACSIN1,PRKCZ,SYTL2,PTCH1,PID1,RDX,KCNIP3,CLIP1,SCP2,KIF13A,SCN3B,TNIK,NFASC,CLASP2,EPB41L3,STXBP1,TSC2,TUB,WNK3,GOPC,TTC7A" GO: Biological Process GO:1900271 regulation of long-term synaptic potentiation 7.59E-06 7.44E-02 2.62E-04 2.56E-03 14 23 "CX3CR1,DRD1,NPTN,PTPN5,HNRNPK,NF1,NOS1,NRGN,NLGN3,RELN,RAB3A,PPP1R9A,STAU1,CRTC1" GO: Biological Process GO:0045685 regulation of glial cell differentiation 8.87E-06 8.70E-02 3.04E-04 2.97E-03 29 71 "BIN1,ASPA,NOG,GPR37L1,QKI,TENM4,DLX1,OLIG2,PRMT5,FGFR3,DLL3,NKX6-2,LINGO1,HES5,IL6ST,MAG,MBD1,MYCN,NF1,NKX2-2,NTRK3,ENPP2,SERPINE2,SIRT2,CNTN2,TCF7L2,DICER1,NR2E1,RTN4" GO: Biological Process GO:0043647 inositol phosphate metabolic process 8.87E-06 8.70E-02 3.04E-04 2.97E-03 29 71 "ADCYAP1R1,SYNJ1,SYNJ2,MTMR2,CALM1,MTMR7,PLCH2,IP6K1,PTK2B,IP6K2,IP6K3,INPP5K,GPER1,INPP1,INPP5B,ITPKA,ITPKB,OCRL,P2RY1,PLCB2,PLCD1,PTAFR,PTH1R,NUDT11,SCP2,SNCA,NUDT10,PLCB1,PLD4" GO: Biological Process GO:0032411 positive regulation of transporter activity 8.96E-06 8.79E-02 3.06E-04 2.99E-03 34 89 "ASIC2,ACTN2,ANK2,ANK3,ASPH,ATP1B3,CACNA2D1,CACNB2,CALM1,HAP1,RGN,SYNGR3,AKAP7,AKAP6,NOS1AP,TCAF1,DMD,DNM2,SGK2,FGF14,KCNJ11,NPPA,HCN1,PIRT,NLGN3,RELN,PTAFR,SGK1,PLCB1,ARC,SGK3,WNK1,WNK3,WNK2" GO: Biological Process GO:2000300 regulation of synaptic vesicle exocytosis 8.98E-06 8.80E-02 3.06E-04 2.99E-03 15 26 "ATP2A2,RIMS4,RIMS2,RIMS3,GRIK5,RAB3A,LRRK2,STX1B,NLGN1,RAB3GAP1,NAPB,RIMS1,STX1A,STXBP1,SYN1" GO: Biological Process GO:0061024 membrane organization 9.12E-06 8.95E-02 3.10E-04 3.02E-03 256 1091 "SYS1,ACTN2,ADCY6,ADORA1,NLGN4X,AP1B1,GPR158,HACE1,TBC1D14,OSBPL8,SYT13,DOC2A,OGT,DPP10,ANK1,ANK2,ANK3,CNIH2,PPFIA1,ANXA7,PRX,SPTBN4,NUMB,DYNLL1,ATP1B3,STX16,ATP2A2,BBS2,BID,CDK5R1,SGCE,RAB29,MYRF,CACNA1A,CACNB2,KALRN,CAMK2A,CAPN3,SYT6,MAP7,CDH2,EVI5L,CHM,TAOK2,CLCN3,NRXN1,NRXN2,CLU,CLTC,HECTD1,RAB26,PICK1,BAG4,CLIP3,SEC24C,CNTNAP2,CALY,APPL1,UBXN2A,USP6NL,MYADM,TCAF1,SNPH,TBC1D5,TMEM170A,TOMM20,SIRPA,DBN1,ELMO1,CNIH3,MAGI2,BLOC1S6,POM121,SNAP91,SGSM2,RABGAP1L,SEC16A,DLG2,DLG3,DLG4,DMPK,TRAPPC9,DNM2,DOCK2,DPP6,PDCD6IP,DNM1L,FIS1,TSPAN5,SYT15,OPTN,SH3GLB1,EGFR,GOLGA7,DMTN,MTSS1L,GPHN,STX2,ERBB2,F5,REEP2,F8,TBC1D16,ATP8A1,RACK1,FCGR1A,SEC24B,FGF13,BAIAP2,VTI1B,ANKFY1,SGIP1,SYT3,FOLR2,TMEM175,SORBS1,NSG2,NSG1,OGA,FYB1,RAPGEF6,NEK6,SYT17,ATP8A2,INPP5K,PCDH17,GLRB,FERMT2,GPER1,GRIA1,GRIK2,GRIK5,GSN,IL1RAPL1,ATG4C,PACSIN2,NCKAP1L,HPCA,HSP90AA1,C2CD4C,KCNB1,SYTL4,ZFYVE27,LYPLAL1,MBP,SYT9,BLOC1S2,MT3,MYO5A,NRCAM,TBC1D25,OPA1,P2RX7,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,NLGN3,PIK3C2A,PIK3R1,PMP2,PACSIN1,FA2H,PPP3CC,PRKCB,RAB39A,PRKCZ,MAPK8,RELN,SYTL2,PTCH1,PTN,PTPRD,PEX5,RAB3A,PID1,SH3TC2,FAT4,RDX,RPL15,ATP8B4,GLDN,SGSM1,RPL38,RPS20,KCNIP3,KCNIP2,CLIP1,STX1B,LRRTM4,SCP2,MYO18A,NLGN1,SEC31A,RPH3A,PEX26,RAB3GAP1,CCDC88A,RTP5,NAPB,IFT122,RIMS1,SNAP25,SNCA,KIF13A,SCN3B,TNIK,SPTB,NFASC,ATP10B,CLASP2,EPB41L3,LRRC4,FCHO1,STX1A,STXBP1,NSFL1C,SYT11,SYNE2,VAMP1,ARHGEF9,SYP,SYT1,ANKRD28,SYT4,SYT5,ATP11A,MTCL1,CNTN2,ANO4,AZIN2,CRB1,TIAM1,TIE1,PARD3,TP53BP2,ZMYND8,TSC2,RFTN2,TUB,TMEFF2,GORASP1,MTCH1,TBC1D15,TRIM9,REEP1,MFF,EVI5,WNK3,PLSCR4,PARP11,GOPC,NUP214,TTC7A,AAAS" GO: Biological Process GO:0016198 axon choice point recognition 9.18E-06 9.00E-02 3.10E-04 3.03E-03 7 7 "APP,EFNB3,FOXG1,GAP43,ROBO1,ROBO2,ROBO3" GO: Biological Process GO:0019228 neuronal action potential 9.31E-06 9.13E-02 3.14E-04 3.07E-03 20 41 "ANK3,CACNA1I,DPP6,DRD1,KCNMB2,KCNMB4,GPER1,RAPGEF4,GRIA1,GRIK2,KCNA1,KCNA2,KCND2,KCNMA1,GPR88,MYH14,SCN2A,SCN3A,SCN7A,SCN8A" GO: Biological Process GO:0032271 regulation of protein polymerization 9.71E-06 9.52E-02 3.26E-04 3.18E-03 58 183 "ADD1,ADD2,APC,SPTBN4,WASF1,SLIT2,PICK1,BAG4,GDA,CLIP3,MYADM,DBN1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,ARFIP1,PSRC1,STMN2,TPPP,GSN,NCKAP1L,SCIN,STMN1,MAPT,DBNL,PAK3,TMOD2,MAGEL2,MAPK8,RDX,KIRREL1,CLIP1,AP1AR,SGK1,PPP1R9A,FHOD3,SNCA,SPTAN1,SPTB,CLASP2,KANK1,MLST8,CLASP1,TMOD1,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B,SLC39A12" GO: Biological Process GO:0033555 multicellular organismal response to stress 9.81E-06 9.62E-02 3.27E-04 3.20E-03 35 93 "ADCYAP1R1,ALS2,PDE8B,CACNA1A,CACNA1B,CACNA1E,KALRN,CCK,BRINP1,DBI,GIT2,LYPD1,DRD1,EDNRB,EIF4G1,GABRA5,GRIK1,GRIK2,GRM7,MEF2C,NCAM1,NEUROD2,NOS1,PIRT,PENK,PPP3CA,PRKCG,RELN,RET,KCNIP3,ANKFN1,TAC1,TACR1,THBS4,NR2E1" GO: Biological Process GO:0051952 regulation of amine transport 9.81E-06 9.62E-02 3.27E-04 3.20E-03 35 93 "ABAT,ADORA1,ADORA2A,AGT,ATP1A2,CACNA1A,CCK,CHGA,CHRNA4,CHRNB2,CNR1,DPYSL2,DRD1,GABBR1,GCK,GRIK1,NR3C1,GRM7,HRH3,HTR2A,KCNA2,KCNB1,NAT8L,OXTR,P2RX7,P2RY1,PLCD1,PRKCB,SLC6A1,RAB3GAP1,SNCA,STX1A,TRH,P2RY12,RTN4" GO: Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling 1.02E-05 9.99E-02 3.39E-04 3.31E-03 54 167 "ADORA3,AGT,FGF17,CD86,NRG2,NCOR1,PPP1R16B,NYAP1,EDN1,RASGRP1,EGFR,PLEKHA1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,STAMBP,FYN,GAB1,GPER1,HTR2A,IGF1,JAK2,KIT,PIK3AP1,KITLG,NF1,NTRK2,PDGFRA,SERPINE2,PIK3CD,PIK3R1,PLXNB1,PPP2R5C,MAPK3,RELN,PTK2,PTPN13,PRR5L,PREX2,SIRT2,MYO16,UNC5B,TEK,SIRT1,PIK3R5,TSC2,UBE3A,VAV1" GO: Biological Process GO:0021510 spinal cord development 1.04E-05 1.02E-01 3.44E-04 3.36E-03 40 112 "ASCL1,CHRD,CACNA1A,PTBP2,NOG,SLIT2,AKAP5,DCC,MED12,DPYSL2,OLIG2,ERCC2,ACTL6B,NKX6-2,GLI2,MDGA1,NEFH,NF1,NKX2-2,NOVA1,PAX6,PKD1,PROX1,RELN,MDGA2,PTCH1,PTN,RFX4,DRAXIN,FUZ,IFT122,SOX1,SOX11,ZC4H2,TAL1,DICER1,VLDLR,ZIC1,GDPD5,IFT88" GO: Biological Process GO:0072659 protein localization to plasma membrane 1.07E-05 1.05E-01 3.53E-04 3.45E-03 68 225 "SYS1,ACTN2,ADCY6,GPR158,DPP10,ANK1,ANK2,ANK3,PPFIA1,SPTBN4,NUMB,ATP1B3,BBS2,CACNB2,KALRN,MAP7,CDH2,NRXN1,CLTC,HECTD1,RAB26,BAG4,CLIP3,APPL1,MYADM,DPP6,TSPAN5,OPTN,GOLGA7,RACK1,FGF13,VTI1B,SORBS1,FYB1,RAPGEF6,INPP5K,GPER1,KCNB1,ZFYVE27,LYPLAL1,MYO5A,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,PIK3R1,PACSIN1,PRKCZ,SYTL2,PTCH1,PID1,RDX,KCNIP3,CLIP1,SCP2,KIF13A,SCN3B,TNIK,NFASC,CLASP2,EPB41L3,STXBP1,TSC2,TUB,WNK3,GOPC,TTC7A" GO: Biological Process GO:0055082 cellular chemical homeostasis 1.09E-05 1.07E-01 3.59E-04 3.50E-03 188 768 "ADCY5,ADCYAP1R1,SLC12A5,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,C1QTNF3,OGT,ANK2,ANXA7,APP,AQP4,AQP6,ARRB1,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CACNA1A,CACNA1E,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,BRSK2,CCKBR,RGN,CD38,SOCS6,CLCN3,NRXN1,SLC24A2,ABCG2,MAP4K4,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,DBI,HEPH,C2CD2L,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,SIDT2,EPHA5,PTK2B,RACK1,RGPD5,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,PPARGC1A,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIK5,GRIN1,GRM1,HRH3,HMGB1,HMGCR,HNRNPK,HTR2A,IGF1,IL6ST,ITGAV,JAK2,SLC35G1,KCNB1,KCNJ11,KCNK3,KCNMA1,AQP11,MT3,MYO5A,MYT1,NEUROD1,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PIK3R1,PKD1,PLCD1,FXYD1,SLC25A23,POLG,PPP3CA,PPP3CB,PRKCB,RAB39A,SLC26A11,FITM2,PTH1R,PTK2,PTPRN,PTPRN2,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,SGK1,HKDC1,SYBU,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SMARCA4,SNCA,WDTC1,TAC1,TACR1,TCF7L2,TPCN2,ATP13A2,TF,SIRT1,TIAM1,STXBP4,TRPC1,TRPC3,TRPM2,TTPA,SGK3,UBTF,VSNL1,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:1904062 regulation of cation transmembrane transport 1.13E-05 1.11E-01 3.71E-04 3.63E-03 71 238 "ASIC2,ACTN2,AGT,PLA2G6,DPP10,ANK2,ANK3,KCNAB2,ASPH,ATP1A2,ATP1B3,CACNA1D,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,CAPN3,RGN,CBARP,STOML1,AKAP7,AKAP6,NOS1AP,DBI,DMD,DNM2,DPP6,DRD1,EDN3,EDNRA,PTK2B,FGF12,FGF14,FHL1,CAB39,JPH4,GPER1,KCNC1,KCNC2,KCNH2,KCNJ11,KCNN2,MYO5A,NOS1,NPPA,HCN1,OPRL1,PDE4B,PDE4D,PIRT,PDPK1,PIK3C2A,FXYD1,KCNIP3,KCNIP2,KCNIP1,SCN2B,SCN4B,SLC8A1,SLN,SNCA,SCN3B,PLCB1,TRPC1,KCNE5,KCNAB1,WNK3,WNK2,JPH3" GO: Biological Process GO:0051705 multi-organism behavior 1.19E-05 1.17E-01 3.88E-04 3.79E-03 34 90 "NLGN4X,ANXA7,APP,NCOA1,KALRN,CHRNB2,NRXN3,NRXN1,NRXN2,CNTFR,CRHBP,CNTNAP2,BRINP1,DLG4,SHANK1,DRD1,PPP1R1B,GAD1,KIRREL3,GLS,GRID1,GRIN1,OXTR,PENK,NLGN3,SERPINE2,PPP3CB,NLGN4Y,SHANK2,VPS13A,DNAJC9,TACR1,THRA,NR2E1" GO: Biological Process GO:0045596 negative regulation of cell differentiation 1.22E-05 1.20E-01 3.98E-04 3.88E-03 172 694 "ADCY6,AXIN2,NR0B1,DISP3,SEMA6A,SEMA7A,PI16,APBB1,APP,SEMA4G,ARHGDIA,ARNTL,ASCL1,DACT3,CHRD,CFLAR,BMP7,CDK5R1,C1QC,RAB29,LDLRAD4,CAPN3,RUNX1T1,ARHGEF1,CBFA2T2,ARHGEF2,NOG,GPR37L1,ADGRG1,SLIT2,NGEF,FBXO7,TJP2,MAP4K4,CRMP1,NCOR2,ABCG1,AATK,SOCS5,CMTM5,HDAC4,BRINP1,DCC,KIAA0319,NTM,DLX1,FAM57B,EDNRB,SEMA3D,OLIG2,DMTN,LRRC17,SEZ6,ERBB2,ERBB4,CDKL3,ADGRV1,PTK2B,EFEMP1,PRMT5,OLFM1,FGF13,FGFR1,FGFR3,MAD2L2,FOXG1,SEMA6C,FOXO3,SEMA4D,DLL3,NRG3,NKX6-2,MSTN,GFAP,GLI2,LILRB4,GPER1,STMN2,C1QL4,PLPP7,CIT,SOX21,LINGO1,HMGB1,IGF1,RBPJ,HES5,ITGAV,ITPKB,LMO2,MAG,MBD1,MBP,MEIS1,MEIS2,MT3,MYCN,NF1,NFE2L2,NKX2-2,NODAL,NPR2,NTRK3,NUCB2,OMG,PAX6,PBX1,GPR173,NLGN3,SEMA5B,PIK3R1,PMP22,TNPO2,FAT3,PPARA,MED1,PPP3CA,PTCH1,PTHLH,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RORB,SOX8,AP1AR,S100B,SALL1,SEMA6D,DRAXIN,FUZ,NLGN1,SIRT2,SLIT1,CDK5RAP2,SOX2,SOX3,SOX11,SPP1,RAP1GAP2,SPART,PBLD,MESP1,KANK1,SEMA4A,CNTN2,TCF7L2,ZEB1,DICER1,SIRT1,ZFPM2,TGFBR3,HEY1,TLR4,NR2E1,HEY2,TNR,TTC3,TTPA,EIF4ENIF1,GORASP1,P2RY12,WNT7A,ZBTB16,RGMA,TMEM178A,SEMA3B,ITM2C,RTN4" GO: Biological Process GO:0010660 regulation of muscle cell apoptotic process 1.24E-05 1.22E-01 4.02E-04 3.93E-03 27 65 "RBM10,AGT,ARRB1,ARRB2,BMP7,CAMK2A,CAMK2D,QKI,EDN1,ERBB4,PTK2B,APOPT1,HMGCR,IGF1,RBPJ,IL12A,JAK2,LIFR,NACA,NFE2L2,PDE1A,PDPK1,PIK3R1,MAPK8,DICER1,SIRT1,HEY2" GO: Biological Process GO:1903305 regulation of regulated secretory pathway 1.26E-05 1.23E-01 4.05E-04 3.96E-03 48 144 "ABR,ADORA3,SYT13,DOC2A,CADPS,ATP2A2,CACNA1I,CACNA1G,CDK5R2,CACNA1A,SYT6,CBARP,RIMS4,RIMS2,RIMS3,SYT15,PRAM1,FER,FGR,SYT3,SYT17,GRIK5,C2CD4C,KCNB1,SYTL4,SYT9,SCAMP5,PDPK1,SYTL2,PTAFR,RAB3A,LRRK2,STX1B,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,TRIM9,C12orf4" GO: Biological Process GO:0071705 nitrogen compound transport 1.26E-05 1.23E-01 4.05E-04 3.96E-03 211 879 "ABAT,ADCY5,SLC12A5,ADORA1,ADORA2A,ADORA3,SLC44A5,AGT,PLA2G6,C1QTNF3,LTBP4,PPFIA4,PPFIA2,PPFIA1,PPFIA3,AQP6,SLC7A14,MADD,ARNTL,ARRB1,CADPS,PDE8B,ATP1A2,RIPK1,BMP7,ARHGEF7,BTK,CACNA1A,CACNA1D,CACNA1E,CACNB4,CAMK2G,BRSK2,CCK,CCKBR,CD38,CACNA2D2,NPIPA1,SRSF11,CHGA,CHRNA4,CHRNB2,NRXN1,ABCG2,QKI,MAP4K4,CNR1,PICK1,AHCTF1,MYRIP,CLOCK,CRHBP,SLC32A1,CRYM,RIMS2,TOMM20,C2CD2L,ZC3H11A,POM121,SMG7,G3BP2,SLC29A4,DPYSL2,DRD1,EDN1,EDN3,EDNRA,SIDT2,EGFR,EPHA5,SLC43A2,SRRM1,TLR7,CD320,PRKAG2,RGPD5,FOLR2,OGA,GABBR1,ILDR2,CPLX1,GCK,GJB1,RNPS1,GLS,GLUL,GNAS,GPM6B,GPER1,PCLO,RAPGEF4,GRIK1,NR3C1,GRM2,GRM7,HRH3,DDX19B,HMGCR,AGFG1,HTR2A,ICA1,SLC6A17,JAK2,KCNA2,KCNB1,KCNC2,KCNJ10,KCNJ11,KIF5C,SYTL4,NAT8L,MAOB,AQP11,SYT9,DDX25,MYO5A,MYO6,MYT1,NEUROD1,NF1,SLCO1C1,NNAT,NOS1,NTRK2,NUCB2,OXTR,P2RX7,P2RY1,PAX6,PDE1C,PDE3B,PFKFB2,ABCB1,PLCD1,SLC25A23,SLC36A4,PPM1B,PPP3CA,PPP3CB,PRKAB2,PRKCB,SIDT1,PTPRN,PTPRN2,RAB3A,SLC6A15,RFX3,SLC25A36,NCBP3,ATXN2,SMPD3,SEC14L1,CASC3,SYBU,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,SLC12A2,SLC14A1,SLC15A2,SLCO1A2,SLC22A4,RIMS1,SNAP25,SNCA,LMBRD1,NXT2,STX1A,STXBP1,ABCC8,SYT1,FBXW11,SMG6,TCF7L2,AZIN2,SLC19A3,ATP13A2,SIRT1,SLC44A1,TIAM1,TLR4,TRH,STXBP4,TRPM2,TSC1,RFTN2,TST,VGF,VSNL1,P2RY12,SLC13A3,XPO1,UPF3A,SLC38A1,SLC17A7,FIP1L1,SLC17A6,PARP11,RTN4,HNRNPA3,NUP214,NLRP3,AAAS" GO: Biological Process GO:0009187 cyclic nucleotide metabolic process 1.47E-05 1.44E-01 4.71E-04 4.60E-03 63 206 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,AMPD2,APLP1,PDE8B,ATP2B2,CACNB4,CALM1,CBS,CHGA,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,RACK1,CAP2,GABBR1,GALR1,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,HPCA,P2RY13,NF1,NOS1,NPPA,NPR2,NUCB2,OPRL1,PALM,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7,PTHLH,MRAP2,GPR161,VIPR2" GO: Biological Process GO:0050919 negative chemotaxis 1.47E-05 1.44E-01 4.71E-04 4.60E-03 20 42 "SEMA6A,SEMA7A,SEMA4G,NRP2,SLIT2,PLXNA4,SEMA3D,SEMA6C,SEMA4D,NRG3,ITGAV,SEMA5B,ROBO1,ROBO2,SEMA6D,SLIT1,SEMA4A,ROBO3,FLRT2,SEMA3B" GO: Biological Process GO:0040008 regulation of growth 1.51E-05 1.49E-01 4.84E-04 4.73E-03 177 720 "NDRG3,ADRB2,AGT,SEMA6A,LTBP4,SEMA7A,PI16,APBB1,APBB2,GPAM,APP,SHTN1,CPNE5,SEMA4G,SPTBN4,CAPRIN2,DACT3,CCAR2,ADAM15,AZGP1,BBS2,CDK5R1,FOXK1,DDR1,CAMK2D,CAPN3,CD38,CD81,CDK11B,CDC42,LGI1,NOG,CACNA2D2,SOCS6,TAOK2,SLIT2,CPNE6,NIPBL,AKAP6,NCOR1,AATK,CSF1,SOCS5,PLXNA4,CTH,RIMS2,KIF26A,IST1,DBN1,DCC,DNM2,DPYSL2,DSCAM,SGK2,SEMA3D,EGFR,PLXNC1,EIF4G2,ING4,RASGRP2,ERBB2,ERBB4,CDKL3,CD320,ACSL4,PTK2B,RACK1,KIAA1109,OLFM1,FGF13,FGFR1,FGFR3,MAD2L2,FHL1,UBE2E3,IP6K2,FOXM1,SEMA6C,SEMA4D,SYT3,CELF1,CGREF1,CSPG5,NRG3,GAP43,TMEM8B,SYT17,DISC1,ATP8A2,MSTN,GDF9,GHR,BRD8,KDM2B,GNAS,GNG4,PSRC1,NR3C1,FAM107A,MAEL,IGFBPL1,HNRNPK,IRF8,IFI16,IGF1,IGFBP1,NKD1,RBPJ,KCNK2,L1CAM,MAPT,MEF2C,CPNE9,MT1M,MT3,N6AMT1,MYH6,NACA,NCAM1,NELL2,NPPA,NRCAM,NTRK3,IGSF11,OMG,SERPINE2,SEMA5B,FTO,LRP12,ING3,POU3F2,PRKCB,PROX1,PTCH1,PTK2,PEX5,USP47,SEMA6D,SBF1,DRAXIN,ATXN2,IL17RB,SGK1,ARX,CLSTN1,SLIT1,EPC1,SMARCA4,RIMS1,MBD5,SOX15,SPP1,TSPYL2,SPART,CLASP2,EPB41L3,PLCB1,SYT1,SYT4,SEMA4A,TAF9,WWC1,TCF7L2,SIRT1,ZMAT3,TLL2,HEY2,TNR,TRO,SGK3,HEPACAM,WRN,RGMA,SEMA3B,HRASLS,RTN4,SOCS4" GO: Biological Process GO:0051174 regulation of phosphorus metabolic process 1.53E-05 1.50E-01 4.87E-04 4.76E-03 392 1769 "NDRG2,ADAR,ELFN2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,ADGRF5,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,APC,APLP1,ALS2,APOC1,APOC2,LRRC4C,APP,SLC7A14,CDK10,PPP4R4,MADD,SPTBN4,ZFYVE28,ARRB1,ARRB2,CAPRIN2,DYNLL1,ATM,EIF4G3,RIPK1,BARD1,BLM,KSR1,BMP7,CDK5R1,C5,CDK5R2,LDLRAD4,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CBS,CCK,LDB2,CCKBR,CCNH,CCNT1,RGN,SCARB1,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,NOG,CRLF1,GPR37L1,CHGA,SOCS6,TAOK2,SLIT2,CLU,FBXO7,MAP4K4,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,AKAP12,CRY2,NCOR1,CLIP3,CSF1,CSF1R,VCAN,SOCS5,PPP1R16B,CTNND1,PPP6R2,RUBCN,MYADM,HDAC4,RASSF2,DCC,ZEB2,MAGI2,SMG7,PARD6A,DLG2,DLG3,DMD,CDON,DRD1,ABI1,DSCAM,RCAN1,DUSP9,DNM1L,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,HIPK3,RASGRP1,SH3GLB1,CELSR3,EGFR,SORBS3,TENM1,TNK2,CALCRL,DMTN,EPHB1,ERBB2,ERBB4,DNAJC27,TLR7,PTK2B,TAOK3,DLC1,RACK1,FKTN,STRADA,PRMT5,PPP1R1B,FECH,FER,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,CAP2,AGAP2,RGPD5,FOXM1,SEMA4D,FLT1,ZBED3,NPTN,CAMKK2,NRG3,FYN,GAB1,GABBR1,CAB39,ZMYND11,GALR1,ZNF274,INPP5K,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,PCDH11X,GNAL,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,C1QL4,GRIK2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,GUCY1A2,GUCY1A1,MAP4K5,IRAK3,HRH3,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HPCA,HTR2A,MYLK2,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,INSM1,LRRTM3,LRRTM1,ITGAV,ITPKB,JAK2,KIT,LRRC4B,CAMK2N2,FGFBP3,PIK3AP1,MDFI,MEF2C,KITLG,MID1,DBNL,MT3,P2RY13,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,NUCB2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PALM,PAX6,PC,PDE2A,PDE4D,PDGFRA,ENPP2,PDPK1,PFKFB2,PGAM2,DUSP26,PIK3R1,PKD1,PLCD1,PLCL1,SLC25A23,PPARA,PPP1R1A,PPP2R2B,PPP2R2C,LRRN3,PTPA,PPP2R5C,PPP2R5E,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCZ,MAPK3,MAPK7,MAPK9,MAPK10,DIRAS2,PROX1,RELN,SYTL2,PTAFR,PTHLH,PTH1R,PTK2,PTPRZ1,PPP2R3C,PID1,RAD17,DUSP15,RET,RGS3,RGS4,KIRREL1,MRAP2,FBXW7,PRR5L,LRRK2,CSRNP3,ATXN1,ATXN7,LRRTM4,FNIP1,TNFRSF19,ITSN1,PPP1R9A,PPM1E,MAGI3,AMBRA1,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,TMEM132D,MAPKBP1,SNCA,LMBRD1,SOX2,TNIK,DBNDD2,TSPYL2,RBM26,LMO3,TAB2,PBLD,STOX1,SAMSN1,LRRC4,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,SMG6,NSD1,TEK,TF,DICER1,SIRT1,LEFTY2,GPR161,AKTIP,THBS4,TIAM1,TLR4,ZFP91,RIMBP2,TNFRSF1B,PARD3,PIK3R5,IL34,NTSR2,TSC1,TSC2,UBC,UCHL1,FLRT2,FLRT1,VAV2,VIPR2,MICAL1,VLDLR,WNT7A,RICTOR,ELFN1,NDRG4,WNK1,PMEPA1,MAP3K12,LRP8,RGMA,WNK3,WNK2,NELFE,VANGL2,SOCS4" GO: Biological Process GO:0043266 regulation of potassium ion transport 1.56E-05 1.53E-01 4.96E-04 4.85E-03 34 91 "ACTN2,ADORA1,ADRB2,DPP10,ANK2,ANK3,KCNAB2,ATP1B3,CACNA1D,AKAP7,AKAP6,AKAP5,NOS1AP,DNM2,DPP6,DRD1,EDN3,PTK2B,FHL1,CAB39,GCK,HTR2A,KCNC1,KCNC2,KCNH2,KCNN2,NOS1,NPPA,KCNIP3,KCNIP2,KCNIP1,ABCC8,KCNE5,KCNAB1" GO: Biological Process GO:2000177 regulation of neural precursor cell proliferation 1.68E-05 1.65E-01 5.32E-04 5.20E-03 35 95 "DISP3,ASCL1,PTBP2,CDH2,NOG,GPR37L1,ADGRG1,CX3CR1,DCT,CDON,CEND1,FOXG1,FOXO3,DISC1,GLI2,KDM2B,RAPGEF1,IGF1,INSM1,LIMS1,AFDN,NF1,PAX6,PROX1,PTPRZ1,LRRK2,SALL1,LIMS2,SIRT2,SMARCD3,SOX2,SOX10,TF,NR2E1,FZD3" GO: Biological Process GO:0061387 regulation of extent of cell growth 1.73E-05 1.70E-01 5.47E-04 5.34E-03 41 118 "SEMA6A,SEMA7A,SHTN1,SEMA4G,CDK5R1,SLIT2,AATK,PLXNA4,IST1,DBN1,DCC,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,FGF13,SEMA6C,SEMA4D,DISC1,L1CAM,MAPT,MT3,NRCAM,NTRK3,OMG,SEMA5B,SEMA6D,DRAXIN,SLIT1,SPP1,SPART,CLASP2,SEMA4A,TNR,RGMA,SEMA3B,RTN4" GO: Biological Process GO:0090075 relaxation of muscle 1.75E-05 1.72E-01 5.50E-04 5.37E-03 16 30 "ADORA1,ATP1A1,ATP1A2,ATP2A2,CAMK2D,CAMK2G,CHGA,AKAP6,MRVI1,GUCY1A1,KCNMA1,P2RY1,PDE4B,PDE4D,SLC8A1,SLN" GO: Biological Process GO:1901698 response to nitrogen compound 1.96E-05 1.93E-01 6.16E-04 6.01E-03 231 981 "SERPINA3,ABAT,ACTN2,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1B,ADRB2,AGT,OSBPL8,ALAD,OGT,APLP1,UPRT,GPAM,APP,ASCL1,ASPH,ATP1A2,ATP2A2,ATP6V1G2,ATP6V0A1,BCHE,HCN2,BLM,BMP7,CDK5R1,CALM1,KALRN,CAMK2A,CBS,P2RX6,AIFM1,NEURL1,ARHGEF2,CDO1,CHRM1,CHRM4,CHRNA4,CHRNB2,SLIT2,SLC22A6,ABCG2,CNGA3,CNR1,AKAP7,AKAP6,AKAP5,CPS1,CREM,CRHBP,CRY2,NCOR1,NCOR2,APPL1,HDAC9,LYPD1,DLG4,DNM2,CPEB2,DPYSL2,DRD1,EDN1,EDNRA,EGFR,DMTN,RRAGB,PTK2B,PPP1R1B,FER,BAIAP2,FOXM1,FOLR2,SORBS1,TRIM16,ATP6V1H,FYN,GAB1,GABBR1,GABRA1,GABRB1,GABRB3,GABRG2,AHCYL1,INPP5K,GATM,GCK,MSTN,SESN1,GHR,PPARGC1A,GLRB,GNAL,GNAO1,GNAS,GNG3,GNG4,GPD1,GPR22,GPER1,GRB10,RAPGEF1,GRIN1,GSN,PTPN5,GUCY1B1,IRAK3,HRH3,HNMT,HNRNPK,HPCA,HTR2A,IGF1,IGFBP1,ITGAV,JAK2,KCNC1,KCNC2,KCNJ11,KCNK1,KCNQ3,KHK,IPO5,SMAD1,MAT2A,MBD1,MEF2C,MOG,SESN3,MT3,MTR,MYO5A,NCAM1,NEFH,VWA2,NOS1,NPPA,HCN1,NTRK2,NUCB2,OGG1,OXTR,P2RX7,TREM2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDE1B,PDGFRA,PDPK1,GPR173,GNG2,PENK,SSH1,PIK3C2A,PIK3R1,PKM,PLCD1,PPARA,PPP3CA,PPP5C,PRKACB,PRKAR1B,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,MAPK9,PTAFR,PTK2,PTN,PTPRE,CASTOR1,PTPRN,PYGM,QDPR,PID1,RGS10,RNASEL,RPE65,LRRK2,RXRA,RYR1,RYR3,SELL,SGK1,CPEB3,SLC1A2,SLC1A3,SLC6A1,SLC8A1,SLC8A3,SIRT2,CPEB4,SNCA,MBD5,LMBRD1,WDTC1,SST,SSTR1,SSTR2,ERBIN,KANK1,ABCC8,PLCB1,TAC1,TACR1,ADGRL3,ZEB1,TEK,DICER1,SIRT1,ZNF106,TIAM1,TIMP4,METTL3,STXBP4,TRPC3,TSC1,TSC2,RFTN2,VGF,VLDLR,P2RY12,ATP6V0E2" GO: Biological Process GO:0043242 negative regulation of protein complex disassembly 2.01E-05 1.97E-01 6.27E-04 6.12E-03 28 70 "ADD1,ADD2,APC,SHROOM2,SPTBN4,ARHGEF2,DMTN,EPS8,APC2,FGF13,EVL,EML4,STMN2,GSN,IRAK3,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SLN,SPTAN1,SPTB,CLASP2,CLASP1,TMOD1,PLEKHH2" GO: Biological Process GO:0030031 cell projection assembly 2.03E-05 1.99E-01 6.32E-04 6.17E-03 115 436 "TTYH1,ACTN2,TBC1D14,NME5,WDR35,CC2D2A,CEP126,FGD2,APC,SHTN1,BBS2,ARHGEF7,HAP1,NEURL1,SEPT7,CDC42,EVI5L,SLIT2,NRXN1,MAP4K4,CCDC151,ARHGEF6,BAG4,SH2B1,PPP1R16B,ARHGEF4,USP6NL,ARHGAP24,HDAC4,TBC1D5,KIAA0586,DBN1,DMD,DNM2,WDPCP,CELSR3,TENM1,DMTN,MTSS1L,STX2,SH3YL1,TBC1D16,ZMYND10,FER,EVL,TMEM107,STAU2,RAPGEF6,NCKAP1,GAP43,DISC1,SEPT9,INPP5K,WASF3,GPM6A,KIF3A,RABL2A,HSP90AA1,KIT,MAP4,POC1B,DBNL,NEFH,CCDC13,NEK1,OCRL,ODF2,OPHN1,P2RX7,PALM,SSH1,SNX10,PLXNB3,PMP22,SPATA6,CEP41,HYDIN,BCAS3,PTPRO,TMEM231,CEP97,CCDC40,RAP1GAP,RDX,RFX2,RFX3,RFX4,KCTD17,KIF27,PPP1R9A,FUZ,NLGN1,DZIP1,ABLIM3,CCDC88A,IFT122,TNIK,CLUAP1,TTBK2,KANK1,FGD4,COBL,RPGRIP1L,DNAH7,ZMYND8,VAV2,TBC1D15,P2RY12,TMEM237,PLPPR5,EVI5,PCDH15,VANGL2,IFT88,SPATA13" GO: Biological Process GO:0051241 negative regulation of multicellular organismal process 2.04E-05 2.00E-01 6.34E-04 6.19E-03 261 1127 "ABAT,ABR,NDRG2,ADCY6,AXIN2,ADORA1,ADRA1D,ADRB2,AGT,DISP3,C1QTNF1,C1QTNF3,SEMA6A,AMH,SEMA7A,PI16,APBB1,APC,APOC1,APOC2,APP,AQP4,SEMA4G,MADD,SPTBN4,ARHGDIA,ARRB1,ARRB2,ASCL1,DACT3,CHRD,CHID1,ATP1A1,ATP1A2,ATP2A2,ADGRB1,ADGRB2,ADGRB3,BBS2,BMP7,CDK5R1,BTK,MTMR2,C1QC,RAB29,IL33,LDLRAD4,CAPN3,KRIT1,USP2,RGN,CD86,ARHGEF1,CBFA2T2,CD38,ARHGEF2,NOG,UBE2L6,GPR37L1,ADGRG1,CHGA,SLIT2,NGEF,FBXO7,TJP2,MAP4K4,HS3ST5,CRHBP,CRMP1,CRY2,AATK,SOCS5,CST3,PHF14,CX3CR1,DOCK4,HDAC9,HDAC4,BRINP1,DBN1,DCC,KIAA0319,NTM,DLX1,DRD1,EDN1,EDNRB,SEMA3D,CALCRL,OLIG2,LRRC17,SEZ6,ERBB2,ERBB4,CDKL3,CEND1,MRVI1,PTK2B,EFEMP1,OLFM1,FGF13,FGFR1,FGFR3,MAD2L2,FOXG1,SEMA6C,FOXO3,EVL,SEMA4D,DLL3,NRG3,OGA,NKX6-2,MSTN,GFAP,USP19,HPGDS,GLI2,GNAS,LILRB4,STMN2,CIT,SOX21,LINGO1,GUCY1A1,IRAK3,PTGDR2,NCKAP1L,VSIG4,HMGB1,HMGCR,HNRNPK,IGF1,RBPJ,HES5,IL6R,IL12A,ITPKB,JAK2,KCNK2,KCNMA1,LIMS1,LMO2,MAG,MBD1,MBP,MEF2C,MEIS1,MEIS2,MT3,RSPO2,MDGA1,MYCN,NEUROD2,NF1,NFE2L2,NKX2-2,NODAL,NOS1,NPPA,NPR2,NTRK3,OMG,OXTR,P2RX7,PAX6,PBX1,PDE3B,PDE4B,PDE4D,PDGFRA,GPR173,NLGN3,SERPINE2,SEMA5B,PIK3R1,PMP22,FAT3,MED1,PPM1B,PPP3CA,PRKACB,PTCH1,PTHLH,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,RAP1GAP,FEZF2,RFX4,ROBO1,ROBO2,RORB,FBXW7,LGR4,SOX8,S100B,SALL1,SEMA6D,DRAXIN,ATXN2,FUZ,NLGN1,LIMS2,SIRT2,SLC11A1,SLIT1,CDK5RAP2,IFT122,SOX2,SOX3,SOX11,SOX15,SPP1,RAP1GAP2,SPART,PBLD,MESP1,ERBIN,KANK1,TAC1,SEMA4A,CNTN2,WWC1,TCF4,TCF7L2,TEK,DICER1,SIRT1,ZFPM2,SPX,GPR161,TGFBR3,HHIP,THBS4,TIE1,HEY1,TLL2,TLR4,NR2E1,HEY2,TNNT1,TNR,TTC3,UBC,EIF4ENIF1,AMOT,GORASP1,WNT7A,ZBTB16,WNK1,RGMA,TMEM178A,SEMA3B,ITM2C,WNK3,FZD3,RTN4,NLRP3" GO: Biological Process GO:0021766 hippocampus development 2.10E-05 2.06E-01 6.51E-04 6.36E-03 31 81 "NCOA1,BBS2,CDK5R1,CDK5R2,AKAP5,SLC32A1,ZEB2,DLX1,DRD1,EMX2,EPHA5,EZH1,FGF13,KIRREL3,DCLK2,KIF3A,HNRNPK,HTR5A,KCNA1,NEFH,NEUROD1,OGDH,PROX1,RELN,PTPRZ1,FEZF2,ATAT1,BCAN,NR2E1,TSC1,LRP8" GO: Biological Process GO:1901214 regulation of neuron death 2.12E-05 2.08E-01 6.55E-04 6.39E-03 86 307 "ADORA2A,AGT,ASCL1,ATM,CDK5R1,NAE1,CACNA1A,AIFM1,CDC42,CRLF1,CHGA,CLU,CNTFR,HDAC4,DCC,DLX1,OPTN,EN2,EPHB1,PTK2B,RACK1,FGFR3,AGAP2,FOXO3,STAMBP,FYN,GABRA5,CHL1,GABRB3,GFER,GHR,PPARGC1A,GPR75,TOX3,KDM2B,GRIK2,GRIK5,GRIN1,NR3C1,GRM7,PTPN5,IGF1,JAK2,KCNB1,KCNMA1,LIG4,MEF2C,NRBP2,MT3,NCF2,NF1,NOS1,NTRK2,PAK3,PDPK1,RETREG1,PPARA,PPP2R2B,PPP5C,VSTM2L,PRKCG,MAPK8,PTPRZ1,OXR1,FBXW7,LRRK2,KCNIP3,DRAXIN,ITSN1,AMBRA1,CPEB4,SNCB,SNCA,FAIM2,UNC5B,SRPK2,STXBP1,TRIM2,ATP13A2,SIRT1,BHLHB9,TP53BP2,TRPM2,TSC1,XRCC4,MAP3K12" GO: Biological Process GO:1900372 negative regulation of purine nucleotide biosynthetic process 2.28E-05 2.23E-01 6.97E-04 6.81E-03 20 43 "APLP1,AKAP6,AKAP5,EDN1,EDNRA,EDNRB,GABBR1,GALR1,GRM2,GRM3,GRM7,GRM8,HRH3,HPCA,P2RY13,NUCB2,OPRL1,PALM,PDE2A,PID1" GO: Biological Process GO:0030809 negative regulation of nucleotide biosynthetic process 2.28E-05 2.23E-01 6.97E-04 6.81E-03 20 43 "APLP1,AKAP6,AKAP5,EDN1,EDNRA,EDNRB,GABBR1,GALR1,GRM2,GRM3,GRM7,GRM8,HRH3,HPCA,P2RY13,NUCB2,OPRL1,PALM,PDE2A,PID1" GO: Biological Process GO:0016477 cell migration 2.28E-05 2.24E-01 6.97E-04 6.81E-03 296 1300 "ABR,ABHD6,PLEKHG5,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,MRTFA,CDC42BPA,SEMA7A,APBB1,APBB2,APC,EPB41L5,DGKZ,SHTN1,SHROOM2,SEMA4G,ARHGAP5,ARHGDIA,ARRB2,ASCL1,CHRD,NUMB,ASTN1,ATP1B3,ADAM15,NRP2,CDK5R1,ARHGEF7,C5,CDK5R2,IL33,LDLRAD4,DDR1,LURAP1,CAMK2D,SPAG9,CCK,LDB2,KRIT1,FMNL3,SCARB1,CDC42,CDH2,DCLK1,NOG,ADGRG1,CHGA,JAM2,TAOK2,SLIT2,BAG4,CDC42BPB,CSF1,CSF1R,CSF3R,VCAN,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,ARHGAP24,HDAC4,DAPK3,SIRPA,DCC,ZEB2,ELMO1,KIAA0319,MAGI2,SRGAP3,DRD1,WDPCP,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,CELSR3,EGFR,ABI2,EGR3,PLXNC1,IRAK4,TNK2,EMX2,PLEKHO1,DMTN,EPHB1,EPS8,ERBB4,APC2,CEND1,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FKTN,FER,FGF1,OLFM1,FGF13,FGFR1,FGR,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,NRG3,FYN,GAB1,CHL1,NCKAP1,DISC1,DNER,GBX2,GCNT2,GFRA1,PPARGC1A,KIRREL3,GPM6A,FUT10,GPER1,RAPGEF4,RFFL,GSN,BVES,ATOH8,HAS2,PADI2,NCKAP1L,HMGB1,HSP90AA1,IGF1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INSM1,TUBB2B,ITGA7,ITGAM,ITGAV,JAK1,JAK2,KIT,L1CAM,LAMA2,MAG,MAPT,MARK1,MATK,MATN2,MEF2C,KITLG,MITF,MDGA1,NACA,NBL1,NF1,NFE2L2,NODAL,NRCAM,NRDC,NTRK2,NTRK3,DDR2,OGDH,OLR1,OPHN1,P2RY1,PAK3,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,ANLN,PIK3CD,PIK3R1,PLXNB1,PLXNB3,SCHIP1,MBOAT7,EPB41L4B,FAT3,SH3KBP1,POU3F2,PKN2,PRKCZ,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,FEZF2,RDX,RET,ROBO1,FBXW7,PRR5L,LRRK2,SOX8,SEMA6D,SELL,SGK1,ARX,FERMT1,ASAP3,MYO18A,DOCK10,FUZ,SLC8A1,CCDC88A,ELMO2,SLIT1,SMARCA4,PALLD,USP33,SOX1,SOX10,SPP1,PBLD,CLASP2,MESP1,SST,KANK1,SYNE2,PLCB1,ARC,TAC1,TACR1,SEMA4A,ROBO3,UNC5D,CNTN2,ADGRL3,WWC1,SATB2,CLASP1,TEK,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,PARD3,TNR,TNS1,RBFOX2,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,VAV1,VAV2,P2RY12,WNT7A,NDRG4,ZFAND5,LRP8,SCG2,SEMA3B,FZD3,DOCK8,RTN4,PAK5,VANGL2,SPATA13" GO: Biological Process GO:0010469 regulation of signaling receptor activity 2.29E-05 2.25E-01 6.97E-04 6.81E-03 44 131 "ACTN2,ADORA1,CNIH2,APP,ZFYVE28,ASPH,CALM1,HAP1,CAMK2D,NEURL1,CHRNA4,NRXN1,STOML1,AKAP6,CRHBP,SOCS5,DAPK1,CNIH3,DLG4,DMD,SHANK1,HEYL,CACNG7,CACNG3,CACNG2,PTK2B,JPH4,PPARGC1A,MEF2C,MYO5A,NOS1,P2RY1,PDE4D,NLGN3,MED1,RELN,RASGRF1,RASGRF2,FBXW7,NLGN1,ARC,NETO2,SOCS4,JPH3" GO: Biological Process GO:0015837 amine transport 2.31E-05 2.26E-01 6.97E-04 6.81E-03 36 100 "ABAT,ADORA1,ADORA2A,AGT,ATP1A2,CACNA1A,CCK,CHGA,CHRNA4,CHRNB2,CNR1,SLC32A1,DPYSL2,DRD1,GABBR1,GCK,GRIK1,NR3C1,GRM7,HRH3,HTR2A,KCNA2,KCNB1,NAT8L,OXTR,P2RX7,P2RY1,PLCD1,PRKCB,SLC6A1,RAB3GAP1,SNCA,STX1A,TRH,P2RY12,RTN4" GO: Biological Process GO:0051703 intraspecies interaction between organisms 2.31E-05 2.26E-01 6.97E-04 6.81E-03 23 53 "NLGN4X,ANXA7,KALRN,CHRNB2,NRXN3,NRXN1,NRXN2,CNTNAP2,BRINP1,DLG4,SHANK1,DRD1,GAD1,GRID1,GRIN1,OXTR,NLGN3,PPP3CB,NLGN4Y,SHANK2,VPS13A,DNAJC9,NR2E1" GO: Biological Process GO:0035176 social behavior 2.31E-05 2.26E-01 6.97E-04 6.81E-03 23 53 "NLGN4X,ANXA7,KALRN,CHRNB2,NRXN3,NRXN1,NRXN2,CNTNAP2,BRINP1,DLG4,SHANK1,DRD1,GAD1,GRID1,GRIN1,OXTR,NLGN3,PPP3CB,NLGN4Y,SHANK2,VPS13A,DNAJC9,NR2E1" GO: Biological Process GO:0042490 mechanoreceptor differentiation 2.54E-05 2.49E-01 7.65E-04 7.47E-03 30 78 "ATP2B2,WHRN,SLC4A7,GSDME,USH1C,WDPCP,ADGRV1,SEC24B,FGFR1,FGFR3,GABRA5,GABRB3,CECR2,KIF3A,RBPJ,HES5,KCNMA1,MYCN,MYO6,MYO7A,NTRK2,NTRK3,STRC,FAT4,DICER1,HEY1,HEY2,PCDH15,VANGL2,IFT88" GO: Biological Process GO:0051493 regulation of cytoskeleton organization 2.62E-05 2.57E-01 7.86E-04 7.68E-03 118 452 "ACTN2,ADD1,ADD2,TAOK1,PPFIA1,APC,SHROOM2,SPTBN4,ARHGDIA,CDK5R1,WASF1,ARHGEF2,CDC42,CFL2,SLIT2,PICK1,BAG4,GDA,CLIP3,CSF1R,ARHGEF10,MYADM,DAPK3,DBN1,SHANK1,PDCD6IP,EDN1,ABI2,SORBS3,TENM1,DMTN,EPHA5,EPS8,APC2,PTK2B,DLC1,FER,FGF13,BAIAP2,FGR,EVL,STAU2,NCKAP1,IQGAP2,INPP5K,ARFIP1,PSRC1,GPM6B,EML4,STMN2,CIT,GSN,NCKAP1L,SYNPO,SCIN,STMN1,MAPT,MEF2C,MID1,DBNL,NTRK3,P2RX7,PAK3,PDGFRA,TMOD2,SSH1,PIK3R1,PKD1,PLXNB1,MAGEL2,MAPK3,MAPK8,PROX1,BCAS3,PTK2,CEP97,RDX,KIRREL1,MAP6D1,ATAT1,CLIP1,AP1AR,SGK1,PPP1R9A,PPM1E,ASAP3,FHOD3,SIRT2,CCDC88A,CDK5RAP2,SNCA,MYCBP2,SPTAN1,SPTB,CLASP2,PHLDB1,KANK1,TAC1,TACR1,MLST8,CLASP1,TEK,TMOD1,TPM1,TSC1,TMEFF2,AMOT,PLEKHH2,WIPF1,RICTOR,XPO1,FMN2,SPIRE1,STMN4,WIPF2,ACTR3B,VANGL2,SLC39A12" GO: Biological Process GO:0045937 positive regulation of phosphate metabolic process 2.64E-05 2.59E-01 7.87E-04 7.69E-03 260 1126 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,ADGRF5,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,ALS2,APOC2,CDK10,MADD,ARRB1,ARRB2,CAPRIN2,ATM,EIF4G3,RIPK1,KSR1,BMP7,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CCK,CCNH,CCNT1,RGN,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,CRLF1,GPR37L1,CHGA,TAOK2,CLU,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,AKAP12,CLIP3,CSF1,CSF1R,PPP1R16B,CTNND1,RASSF2,DCC,ZEB2,MAGI2,CDON,DRD1,ABI1,DSCAM,DUSP9,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,RASGRP1,SH3GLB1,EGFR,SORBS3,TENM1,TNK2,CALCRL,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,DLC1,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,CAP2,AGAP2,SEMA4D,FLT1,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,GNAL,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,GRM1,GRM5,PTPN5,GUCY1A2,GUCY1A1,MAP4K5,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HPCA,HTR2A,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,ITGAV,JAK2,KIT,FGFBP3,MDFI,MEF2C,KITLG,MID1,DBNL,MT3,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PC,PDGFRA,ENPP2,PDPK1,PFKFB2,DUSP26,PIK3R1,PKD1,PLCD1,LRRN3,PTPA,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTAFR,PTHLH,PTH1R,PTK2,PTPRZ1,PPP2R3C,PID1,DUSP15,RET,MRAP2,FBXW7,PRR5L,LRRK2,FNIP1,TNFRSF19,ITSN1,PPP1R9A,MAGI3,AMBRA1,ANKRD6,CCDC88A,SLC11A1,MAPKBP1,SNCA,SOX2,TNIK,TAB2,STOX1,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,TEK,TF,SIRT1,LEFTY2,GPR161,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PIK3R5,IL34,NTSR2,UBC,VAV2,VIPR2,VLDLR,WNT7A,RICTOR,NDRG4,MAP3K12,LRP8,RGMA,WNK3,NELFE,VANGL2" GO: Biological Process GO:0010562 positive regulation of phosphorus metabolic process 2.64E-05 2.59E-01 7.87E-04 7.69E-03 260 1126 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,ADGRF5,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,ALS2,APOC2,CDK10,MADD,ARRB1,ARRB2,CAPRIN2,ATM,EIF4G3,RIPK1,KSR1,BMP7,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CCK,CCNH,CCNT1,RGN,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,CRLF1,GPR37L1,CHGA,TAOK2,CLU,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,AKAP12,CLIP3,CSF1,CSF1R,PPP1R16B,CTNND1,RASSF2,DCC,ZEB2,MAGI2,CDON,DRD1,ABI1,DSCAM,DUSP9,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,RASGRP1,SH3GLB1,EGFR,SORBS3,TENM1,TNK2,CALCRL,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,DLC1,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,CAP2,AGAP2,SEMA4D,FLT1,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,RUNDC3A,COPS8,GNAL,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,GRM1,GRM5,PTPN5,GUCY1A2,GUCY1A1,MAP4K5,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HPCA,HTR2A,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,ITGAV,JAK2,KIT,FGFBP3,MDFI,MEF2C,KITLG,MID1,DBNL,MT3,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PC,PDGFRA,ENPP2,PDPK1,PFKFB2,DUSP26,PIK3R1,PKD1,PLCD1,LRRN3,PTPA,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTAFR,PTHLH,PTH1R,PTK2,PTPRZ1,PPP2R3C,PID1,DUSP15,RET,MRAP2,FBXW7,PRR5L,LRRK2,FNIP1,TNFRSF19,ITSN1,PPP1R9A,MAGI3,AMBRA1,ANKRD6,CCDC88A,SLC11A1,MAPKBP1,SNCA,SOX2,TNIK,TAB2,STOX1,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,TEK,TF,SIRT1,LEFTY2,GPR161,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PIK3R5,IL34,NTSR2,UBC,VAV2,VIPR2,VLDLR,WNT7A,RICTOR,NDRG4,MAP3K12,LRP8,RGMA,WNK3,NELFE,VANGL2" GO: Biological Process GO:1904064 positive regulation of cation transmembrane transport 2.67E-05 2.62E-01 7.94E-04 7.75E-03 40 116 "ASIC2,ACTN2,ANK2,ANK3,ASPH,ATP1B3,CACNA2D1,CACNB2,CALM1,HAP1,CAPN3,RGN,AKAP7,AKAP6,NOS1AP,DBI,DMD,DNM2,DPP6,DRD1,EDN3,EDNRA,FGF14,GPER1,KCNC1,KCNC2,KCNH2,KCNJ11,NOS1,NPPA,HCN1,PIRT,PDPK1,FXYD1,SNCA,PLCB1,TRPC1,KCNE5,WNK3,WNK2" GO: Biological Process GO:0034764 positive regulation of transmembrane transport 2.74E-05 2.69E-01 8.11E-04 7.92E-03 51 160 "ASIC2,ACTN2,ANK2,ANK3,CASK,ASPH,ATP1B3,CACNA2D1,CACNB2,CALM1,HAP1,CAPN3,RGN,AKAP7,AKAP6,NOS1AP,TCAF1,DBI,DMD,DNM2,DPP6,DRD1,EDN3,EDNRA,FGF14,GPER1,KCNC1,KCNC2,KCNH2,KCNJ11,NOS1,NPPA,HCN1,P2RX7,PIRT,PDPK1,NLGN3,FXYD1,RELN,PTAFR,SCP2,SNCA,PLCB1,ARC,ACSL6,AZIN2,TRPC1,KCNE5,WNK1,WNK3,WNK2" GO: Biological Process GO:0034767 positive regulation of ion transmembrane transport 2.80E-05 2.75E-01 8.28E-04 8.09E-03 49 152 "ASIC2,ACTN2,ANK2,ANK3,CASK,ASPH,ATP1B3,CACNA2D1,CACNB2,CALM1,HAP1,CAPN3,RGN,AKAP7,AKAP6,NOS1AP,TCAF1,DBI,DMD,DNM2,DPP6,DRD1,EDN3,EDNRA,FGF14,GPER1,KCNC1,KCNC2,KCNH2,KCNJ11,NOS1,NPPA,HCN1,P2RX7,PIRT,PDPK1,NLGN3,FXYD1,RELN,PTAFR,SNCA,PLCB1,ARC,ACSL6,TRPC1,KCNE5,WNK1,WNK3,WNK2" GO: Biological Process GO:0035725 sodium ion transmembrane transport 2.83E-05 2.78E-01 8.34E-04 8.15E-03 44 132 "ASIC2,ASIC1,SLC24A4,AGT,ANK3,SHROOM2,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,HCN2,CAMK2D,ASIC3,SLC24A2,STOML1,SLC4A7,DMD,DNM2,FGF12,KCNK1,NOS1,HCN1,NALCN,FXYD1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC20A2,SCN3B,PLCB1,TRPM2,SLC17A7,WNK3,WNK2" GO: Biological Process GO:0019725 cellular homeostasis 2.85E-05 2.79E-01 8.36E-04 8.16E-03 210 885 "ADCY5,ADCYAP1R1,ADD1,SLC12A5,ADRA1D,ADRA1B,SLC24A4,AGT,TXNDC16,PLA2G6,C1QTNF1,C1QTNF3,OGT,ANK2,ANXA7,APC,APP,AQP4,AQP6,ARRB1,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CACNA1A,CACNA1E,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,BRSK2,CCKBR,KRIT1,RGN,AIFM1,CD38,LARGE1,CFL2,SOCS6,CLCN3,NRXN1,SLC24A2,ABCG2,MAP4K4,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,CYBB,DBI,HEPH,C2CD2L,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,SIDT2,EPHA5,PTK2B,RACK1,RGPD5,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,GAA,JPH4,GALR1,DISC1,GCK,MSTN,PPARGC1A,AIFM3,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIK5,GRIN1,GRM1,HRH3,HMGB1,HMGCR,HNRNPK,HTR2A,IGF1,IL6ST,NME9,ITGAV,JAK2,SLC35G1,KCNB1,KCNJ11,KCNK3,KCNMA1,LAMP2,AQP11,MT3,MYO5A,MYT1,NCF2,NELL2,NEUROD1,NFE2L2,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PIK3R1,PKD1,PLCD1,FXYD1,SLC25A23,POLG,PPP3CA,PPP3CB,PRKCB,RAB39A,SLC26A11,FITM2,PTH1R,PTK2,PTPRN,PTPRN2,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,SGK1,HKDC1,SYBU,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SLC12A2,SLC12A4,SMARCA4,SNCA,WDTC1,TAC1,TACR1,TCF7L2,TPCN2,TNS2,ATP13A2,TF,SIRT1,TIAM1,LRRC8A,STXBP4,TRPC1,TRPC3,TRPM2,TTPA,SGK3,UBC,UBTF,PDIA2,VSNL1,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0014829 vascular smooth muscle contraction 2.85E-05 2.80E-01 8.36E-04 8.16E-03 14 25 "AGT,BBS2,CACNA1G,CHRM1,DOCK4,EDN1,EDN3,EDNRA,EDNRB,HTR2A,PIK3C2A,RAP1GDS1,SMPD3,SLC8A1" GO: Biological Process GO:0072503 cellular divalent inorganic cation homeostasis 2.98E-05 2.92E-01 8.69E-04 8.49E-03 114 435 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,AKAP6,SLC25A27,AKAP5,DBI,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,PTK2B,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,MT3,MYO5A,NOS1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,SLC30A3,SLC30A4,TMEM178A,SLC39A12,JPH3" GO: Biological Process GO:0036465 synaptic vesicle recycling 3.00E-05 2.94E-01 8.72E-04 8.52E-03 16 31 "AMPH,SYNJ1,CANX,DNM1,FGF14,OPHN1,PACSIN1,RAB3A,LRRK2,ITSN1,SH3GL2,NLGN1,SNCA,SYT1,SYT5,WNT7A" GO: Biological Process GO:0031644 regulation of neurological system process 3.03E-05 2.97E-01 8.78E-04 8.58E-03 32 86 "ADORA1,ADRB2,AGT,MTMR2,MYRF,CCK,CCKBR,TENM4,EDN1,EDNRB,FCGR3A,FGFR1,WASF3,RAPGEF4,GRIN2D,GRM1,GRM3,KCNJ10,FGFBP3,MAG,NCAM1,NOS1,OPRL1,PTAFR,TMEM100,TF,DICER1,SPX,TLR4,PARD3,TNR,RTN4" GO: Biological Process GO:0072507 divalent inorganic cation homeostasis 3.05E-05 2.99E-01 8.82E-04 8.61E-03 119 458 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANK3,ANXA7,APP,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,AKAP6,SLC25A27,AKAP5,DBI,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,EGFR,PTK2B,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNK3,MT3,MYO5A,NOS1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,CNNM2,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,SLC30A3,SLC30A4,TMEM178A,SLC39A12,JPH3" GO: Biological Process GO:0097120 receptor localization to synapse 3.07E-05 3.02E-01 8.87E-04 8.66E-03 9 12 "CNIH2,NRXN1,DLG2,DLG3,DLG4,RELN,NLGN1,ANKS1B,NETO1" GO: Biological Process GO:0021700 developmental maturation 3.15E-05 3.09E-01 9.06E-04 8.85E-03 78 275 "APP,SPTBN4,ASCL1,ADGRB3,CDK5R1,BTK,AP1M1,CDK5R2,CACNA1A,CAMK2B,NEURL1,CDC25B,NRXN3,CLCN3,NRXN1,PICK1,CNTNAP2,BLOC1S6,DLG2,DLG4,SHANK1,SEZ6L2,EDNRB,FEM1B,SEZ6,ERBB4,ERCC2,CEND1,PTK2B,FGFR1,FGFR3,FOXO3,SEMA4D,DISC1,C1QL1,RND1,GRIN1,HNRNPK,ZDHHC15,IGF1,RBPJ,HES5,KCNMA1,MYO5A,NEUROD2,NFIA,NPR2,NRCAM,OPA1,PALM,PDE3A,PLP1,PLXNB1,SEPT4,RELN,PTH1R,RAB3A,FAT4,RET,RFX3,GLDN,RPS6KA2,LRRK2,SOX8,KCNIP2,RYR1,SIRT2,SOX10,NFASC,STXBP1,PLCB1,SYP,TAL1,CNTN2,SEZ6L,MTCH1,LGI4,SLC17A7" GO: Biological Process GO:0051261 protein depolymerization 3.18E-05 3.12E-01 9.13E-04 8.92E-03 38 109 "ACTN2,ADD1,ADD2,APC,SHROOM2,SPTBN4,ASPH,SYNJ1,ARHGEF2,CFL2,MICAL2,DNAJC6,KIF19,DMTN,EPS8,APC2,FGF13,EVL,EML4,STMN2,GSN,SCIN,STMN1,MID1,DBNL,TMOD2,RDX,MAP6D1,SGK1,SLN,SPTAN1,SPTB,CLASP2,CLASP1,TMOD1,PLEKHH2,MICAL1,STMN4" GO: Biological Process GO:0001558 regulation of cell growth 3.28E-05 3.21E-01 9.37E-04 9.15E-03 116 445 "NDRG3,AGT,SEMA6A,LTBP4,SEMA7A,PI16,APBB1,APBB2,SHTN1,CPNE5,SEMA4G,CAPRIN2,DACT3,CCAR2,ADAM15,CDK5R1,FOXK1,DDR1,CAMK2D,CD38,CD81,CDK11B,CDC42,LGI1,TAOK2,SLIT2,CPNE6,AKAP6,AATK,PLXNA4,CTH,RIMS2,KIF26A,IST1,DBN1,DCC,DNM2,DPYSL2,DSCAM,SGK2,SEMA3D,EGFR,PLXNC1,EIF4G2,RASGRP2,ERBB2,CDKL3,CD320,ACSL4,PTK2B,RACK1,KIAA1109,OLFM1,FGF13,MAD2L2,FHL1,IP6K2,FOXM1,SEMA6C,SEMA4D,SYT3,CGREF1,NRG3,SYT17,DISC1,GDF9,KDM2B,GNG4,PSRC1,NR3C1,FAM107A,IGFBPL1,HNRNPK,IFI16,IGF1,IGFBP1,L1CAM,MAPT,CPNE9,MT3,N6AMT1,NPPA,NRCAM,NTRK3,OMG,SERPINE2,SEMA5B,PTK2,USP47,SEMA6D,SBF1,DRAXIN,IL17RB,SGK1,CLSTN1,SLIT1,SMARCA4,RIMS1,SPP1,TSPYL2,SPART,CLASP2,EPB41L3,SYT1,SYT4,SEMA4A,TAF9,SIRT1,ZMAT3,TNR,TRO,SGK3,RGMA,SEMA3B,HRASLS,RTN4" GO: Biological Process GO:0032414 positive regulation of ion transmembrane transporter activity 3.38E-05 3.32E-01 9.62E-04 9.40E-03 30 79 "ASIC2,ACTN2,ANK2,ANK3,ASPH,ATP1B3,CACNA2D1,CACNB2,CALM1,HAP1,RGN,AKAP7,AKAP6,NOS1AP,TCAF1,DMD,DNM2,FGF14,KCNJ11,NPPA,HCN1,PIRT,NLGN3,RELN,PTAFR,PLCB1,ARC,WNK1,WNK3,WNK2" GO: Biological Process GO:0014015 positive regulation of gliogenesis 3.39E-05 3.32E-01 9.62E-04 9.40E-03 25 61 "BIN1,ASPA,SYNJ1,NOG,QKI,CSF1,TENM4,OLIG2,PRMT5,NKX6-2,GFAP,IL6ST,MAG,NKX2-2,ENPP2,SERPINE2,PTK2,PTPRZ1,SOX8,ATXN1,SOX10,TF,DICER1,TIAM1,RTN4" GO: Biological Process GO:0010765 positive regulation of sodium ion transport 3.45E-05 3.39E-01 9.79E-04 9.56E-03 20 44 "ADRB2,ANK3,ATP1B3,CNTN1,DMD,DNM2,SGK2,FGF12,FGF14,AHCYL1,GNAS,NOS1,FXYD1,SCN4B,SGK1,SCN3B,PLCB1,SGK3,WNK3,WNK2" GO: Biological Process GO:0032956 regulation of actin cytoskeleton organization 3.48E-05 3.41E-01 9.83E-04 9.60E-03 84 302 "ACTN2,ADD1,ADD2,PPFIA1,SHROOM2,SPTBN4,ARHGDIA,CDK5R1,WASF1,CFL2,SLIT2,PICK1,BAG4,CSF1R,ARHGEF10,MYADM,DAPK3,DBN1,SHANK1,EDN1,ABI2,SORBS3,TENM1,DMTN,EPHA5,EPS8,PTK2B,DLC1,FER,BAIAP2,FGR,EVL,STAU2,NCKAP1,IQGAP2,INPP5K,ARFIP1,GPM6B,CIT,GSN,NCKAP1L,SYNPO,SCIN,MEF2C,DBNL,NTRK3,PAK3,PDGFRA,TMOD2,SSH1,PIK3R1,MAGEL2,PROX1,BCAS3,RDX,KIRREL1,AP1AR,PPP1R9A,PPM1E,ASAP3,FHOD3,CCDC88A,SPTAN1,SPTB,CLASP2,KANK1,TAC1,TACR1,MLST8,CLASP1,TEK,TMOD1,TPM1,TSC1,TMEFF2,AMOT,PLEKHH2,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B,VANGL2" GO: Biological Process GO:0008277 regulation of G protein-coupled receptor signaling pathway 3.49E-05 3.42E-01 9.83E-04 9.60E-03 45 137 "ABHD6,ADRB2,GPR158,KCTD16,ARRB1,RGS20,ARRB2,RGS11,RGS9,CALM1,CAMK2B,CHGA,NMT2,RGS6,GPSM1,GPRASP1,KCTD8,GIT2,DNM1,DNM2,EDN1,PRMT5,GNG4,GPER1,GRK4,GRM5,PTGDR2,GIT1,NOS1,PALM,TMOD2,KLK6,RGS3,RGS4,RGS7,RGS12,RIC8B,LRRK2,SNCA,USP33,PLCB1,SYP,CNTN2,MGRN1,RPGRIP1L" GO: Biological Process GO:0002027 regulation of heart rate 3.61E-05 3.54E-01 1.02E-03 9.92E-03 35 98 "ADRA1B,AGT,ANK2,SPTBN4,ATP2A2,CACNA1G,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALM1,CAMK2D,NOS1AP,DMD,EDN1,EDN3,BVES,KCNH2,MDM4,CTNNA3,MYH6,MYH7,NPPA,PDE4D,PIK3R1,SCN2B,SCN4B,SLC8A1,SCN3B,TAC1,SIRT1,SPX,HEY2,TPM1,KCNE5" GO: Biological Process GO:0060113 inner ear receptor cell differentiation 3.70E-05 3.63E-01 1.04E-03 1.01E-02 28 72 "ATP2B2,WHRN,SLC4A7,GSDME,USH1C,WDPCP,ADGRV1,SEC24B,FGFR1,FGFR3,GABRA5,GABRB3,CECR2,KIF3A,RBPJ,HES5,KCNMA1,MYCN,MYO6,MYO7A,STRC,FAT4,DICER1,HEY1,HEY2,PCDH15,VANGL2,IFT88" GO: Biological Process GO:0090659 walking behavior 3.87E-05 3.80E-01 1.08E-03 1.05E-02 19 41 "SPTBN4,ARRB2,CACNA1A,CACNB4,DRD1,EFNB3,CEND1,GLRB,KCNJ10,KCNMA1,MAPT,OXR1,SCN8A,CNTN2,AGTPBP1,TRH,UCHL1,ZIC1,PCDH15" GO: Biological Process GO:0007628 adult walking behavior 3.87E-05 3.80E-01 1.08E-03 1.05E-02 19 41 "SPTBN4,ARRB2,CACNA1A,CACNB4,DRD1,EFNB3,CEND1,GLRB,KCNJ10,KCNMA1,MAPT,OXR1,SCN8A,CNTN2,AGTPBP1,TRH,UCHL1,ZIC1,PCDH15" GO: Biological Process GO:0006939 smooth muscle contraction 4.10E-05 4.02E-01 1.14E-03 1.11E-02 39 114 "ABAT,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ATP1A2,BBS2,CACNA1G,CHRM1,CHRNB2,DOCK4,DAPK3,DRD1,EDN1,EDN3,EDNRA,EDNRB,CALCRL,MRVI1,FLT1,GPER1,GUCY1A1,HTR2A,KCNMA1,OXTR,PDE4B,PDE4D,PIK3C2A,PTAFR,RAP1GDS1,SMPD3,SMTN,SLC8A1,SSTR2,SULF2,TACR1,TPCN2" GO: Biological Process GO:1900452 regulation of long-term synaptic depression 4.12E-05 4.04E-01 1.14E-03 1.11E-02 8 10 "ADORA1,DGKI,STAU2,KCNB1,MAPT,PPP1R9A,SORCS3,IQSEC2" GO: Biological Process GO:0097119 postsynaptic density protein 95 clustering 4.12E-05 4.04E-01 1.14E-03 1.11E-02 8 10 "CDH2,NRXN1,NRXN2,DBN1,RELN,NLGN1,LRRC4,ZMYND8" GO: Biological Process GO:0006874 cellular calcium ion homeostasis 4.23E-05 4.15E-01 1.16E-03 1.14E-02 108 411 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,AKAP6,SLC25A27,AKAP5,DBI,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,PTK2B,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,MYO5A,NOS1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SMPD3,RASA3,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,TMEM178A,JPH3" GO: Biological Process GO:0051592 response to calcium ion 4.26E-05 4.17E-01 1.16E-03 1.14E-02 42 126 "CPNE2,ANXA7,ASPH,CALM1,CAMK2D,CAPN3,ENTPD6,CPNE6,CRHBP,EDN1,EGFR,RASA4,DMTN,RASGRP2,KCNMB2,ADGRV1,PTK2B,SYT3,AHCYL1,KCNMB4,GRIN1,ITPKB,KCNH1,KCNMA1,MEF2C,NEUROD2,HCN1,P2RX7,PDE1C,PENK,PLCD1,SLC25A23,PPP3CA,CARF,KCNIP2,RYR3,SEC31A,SLC6A1,SYT1,TRPC1,TRPC3,PCDH15" GO: Biological Process GO:0006198 cAMP catabolic process 4.27E-05 4.19E-01 1.16E-03 1.14E-02 12 20 "PDE8B,RACK1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7" GO: Biological Process GO:0015812 gamma-aminobutyric acid transport 4.27E-05 4.19E-01 1.16E-03 1.14E-02 12 20 "ABAT,CACNA1A,CACNB4,SLC32A1,GABBR1,GRIK1,HRH3,NF1,P2RX7,SLC6A1,SLC6A11,TRH" GO: Biological Process GO:0051494 negative regulation of cytoskeleton organization 4.27E-05 4.19E-01 1.16E-03 1.14E-02 43 130 "ADD1,ADD2,PPFIA1,APC,SHROOM2,SPTBN4,ARHGEF2,SLIT2,PICK1,CLIP3,MYADM,DBN1,SHANK1,DMTN,EPS8,APC2,DLC1,FGF13,EVL,INPP5K,EML4,STMN2,GSN,SCIN,STMN1,MID1,DBNL,TMOD2,RDX,MAP6D1,SGK1,PPP1R9A,FHOD3,CDK5RAP2,SNCA,SPTAN1,SPTB,CLASP2,KANK1,CLASP1,TMOD1,TMEFF2,PLEKHH2" GO: Biological Process GO:0021884 forebrain neuron development 4.29E-05 4.21E-01 1.17E-03 1.14E-02 18 38 "NRP2,SLIT2,DRD1,FGFR1,FOXG1,SALL3,DISC1,GBX2,DCLK2,OGDH,FEZF2,ROBO1,ROBO2,ARX,SLIT1,SOX1,CNTN2,SLC4A10" GO: Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 4.50E-05 4.42E-01 1.22E-03 1.19E-02 170 700 "ADORA1,ADRB2,AP2A1,AP2A2,AGT,OSBPL8,ALK,OGT,DGKD,APP,ZFYVE28,ATP6V1G2,ATP6V0A1,FGF17,NRP2,CDK5R1,ARHGEF7,BTK,DDR1,KALRN,HAP1,NEURL1,REPS2,CDC42,NOG,CHN1,EPS15L1,CLTA,NGEF,COL4A5,NRG2,CSF1,CSF1R,SIPA1L1,SOCS5,APPL1,PHF14,CYBB,RASSF2,ELMO1,DNM1,ABI1,EFNA2,EFNA3,EFNB3,APH1A,EGFR,PLEKHA1,TNK2,EPHA5,EPHB1,EPS8,ERBB2,ERBB4,F3,PTK2B,EFEMP1,FER,FGF1,FGF12,FGF14,FGFR1,FGFR3,BAIAP2,FGR,FLT1,SORBS1,NPTN,ATP6V1H,NRG3,FYN,GAB1,NCKAP1,INPP5K,MSTN,GFRA1,GFRA2,GHR,GPER1,GRB10,RAPGEF1,GRIN1,PTPRT,NCKAP1L,HSP90AA1,IGF1,IGFBP1,RBPJ,ITGAV,JAK1,JAK2,KIT,FGFBP3,ZFYVE27,MATK,SHC3,GIT1,MT3,HNRNPM,NCF2,VWA2,NTRK2,NTRK3,DDR2,NUCB2,PAK3,PDGFRA,PDPK1,PIK3C2A,PIK3R1,EPN1,SCHIP1,PILRA,SH3KBP1,POLR2F,PRKCB,PRKCZ,MAPK3,PTK2,PTPRE,PTPRG,PID1,SH3TC2,FAT4,RET,RPE65,EPHA10,FBXW7,MAPK12,ATXN1,ATXN7,ITSN1,SH3GL2,KIF16B,FUZ,SHC4,SIRT2,ELMO2,SNCA,MBD5,LMBRD1,DOK5,CLASP2,SS18,ERBIN,KANK1,SULF2,PLCB1,TCF4,TCF7L2,TEK,SIRT1,ZNF106,HHIP,TIAM1,RBFOX2,STXBP4,TSC1,TSC2,UBC,FLRT2,FLRT1,VAV1,VAV2,ATP6V0E2,NDRG4,ZFAND5,MVB12B,IFT88,SOCS4" GO: Biological Process GO:0032228 "regulation of synaptic transmission, GABAergic" 4.67E-05 4.58E-01 1.26E-03 1.23E-02 17 35 "SYN3,ADORA1,ADORA2A,HAP1,CCKBR,CNR1,DBI,ERBB4,GRIK1,NF1,OXTR,PLCL1,NLGN1,SLC6A1,STXBP1,TAC1,TACR1" GO: Biological Process GO:0008542 visual learning 4.69E-05 4.60E-01 1.26E-03 1.23E-02 25 62 "ADRA1B,APBB1,APP,PDE8B,ATP1A2,ATP1A3,CACNA1E,NOG,CHRNB2,DRD1,PPP1R1B,NPTN,GRIN1,HMGCR,KIT,MEIS2,NF1,PDE1B,NLGN3,PTPRZ1,ATXN1,SGK1,DDHD2,NDRG4,NETO1" GO: Biological Process GO:0001964 startle response 4.97E-05 4.88E-01 1.34E-03 1.31E-02 16 32 "ADORA2A,NRXN1,DBN1,GRIN3A,DRD1,FABP7,GLRB,GRIN1,GRIN2C,GRIN2D,KCNA1,KCNH1,PENK,NPAS3,CSMD1,PCDH15" GO: Biological Process GO:0099612 protein localization to axon 4.99E-05 4.90E-01 1.34E-03 1.31E-02 6 6 "CNTNAP1,CNTNAP2,NFASC,EPB41L3,CNTN2,UGT8" GO: Biological Process GO:0010648 negative regulation of cell communication 5.05E-05 4.95E-01 1.35E-03 1.32E-02 299 1328 "ASIC1,ACHE,ABHD6,NDRG2,ADAR,AXIN2,BRAP,ADORA1,ADRA1B,ADRB2,BEND6,NLGN4X,AP2A1,AP2A2,AGT,NME5,NR0B1,PLA2G6,C1QTNF3,MRTFA,CNIH2,APC,DGKZ,LRRC4C,MADD,ZFYVE28,ARNTL,ARRB1,RGS20,ARRB2,PDE8B,DACT3,PTCH2,CHRD,NUMB,RASL11B,CCAR2,ATM,RIPK1,BCHE,RGS11,RGS9,BCL2L2,CFLAR,BMP7,ARHGEF7,MTMR2,LDLRAD4,BTRC,CALM1,CAMK2B,CD38,NEURL1,DGKI,ARHGEF2,CDC42,CDH2,NOG,GPR37L1,SOCS6,SLIT2,EPS15L1,CLU,SLC24A2,STOML1,CLTA,MAP4K4,PICK1,ZNF385A,PNKD,CLOCK,CRHBP,CRY2,NCOR1,RGS6,FEZ2,FEZ1,CSNK1E,SOCS5,PHF14,CTH,CTNND1,RUBCN,CX3CR1,GPRASP1,MYADM,ARHGAP24,KIF26A,RASSF2,DAPK1,MAGI2,G3BP2,CHRDL1,DLX1,DMD,DNM1,MED12,DNM2,DRD1,DUSP9,DYRK1A,EDN1,EDN3,HIPK3,HEYL,OPTN,SH3GLB1,EGFR,RASA4,PLEKHA1,RGS17,APC2,EYA1,PTK2B,TAOK3,DLC1,RACK1,FKTN,FGFR3,MAD2L2,AGAP2,FOXM1,FOXO3,STAMBP,DLL3,STAU2,FYN,DKK3,GABBR1,ZMYND11,SALL3,INPP5K,GCK,MSTN,SESN1,PCDH17,GPM6B,GPER1,GRK4,RAPGEF4,GRB10,RAPGEF1,GRIA1,C1QL4,RFFL,GRIK1,GRIK2,GRIK3,NR3C1,GRM5,PTPN5,WIF1,IRAK3,PADI2,HMGCR,HTR2A,IGF1,IGFBP1,NKD1,IL6ST,SCRT2,LRRTM3,LRRTM1,ITGAV,KCNB1,KCNJ11,LRRC4B,SYTL4,PIK3AP1,MAPT,MDFI,SESN3,NRBP2,NBL1,NEUROD1,NF1,NFE2L2,NODAL,NOS1,NUCB2,OPA1,P2RX7,PALM,PDE1C,PDE3B,PDPK1,DUSP26,NLGN3,SERPINE2,NLE1,EPN1,MAPKAP1,STRN3,SH3KBP1,PPM1B,PPP3CA,PRKACB,SKOR1,PRKCB,PRKCZ,MAPK7,VPS13C,PSMA6,PSMD13,PTCH1,PTPRE,CASTOR1,PTPRO,PID1,USP47,RFX4,RGS3,RGS4,RGS7,RGS10,RGS12,KIF7,ROBO1,FBXW7,PRR5L,LRRK2,LGR4,AMER2,SALL1,ATXN1,DRAXIN,ATXN7,LRRTM4,FNIP1,SEC14L1,RASA3,PPP1R9A,SH3GL2,FUZ,ANKRD6,SLC6A1,CDK5RAP3,TRIM67,SHANK2,CXXC4,SMARCA4,SORCS3,IFT122,SNCA,FAIM2,LMBRD1,SOX2,SOX10,HECW1,UNC5B,PEG10,IQSEC2,SPART,LMO3,PBLD,MESP1,LRRC4,ERBIN,KANK1,SULF2,STXBP1,SYT11,ABCC8,TAF9,WWC1,FBXW11,MGRN1,VWC2,TCF7L2,RPGRIP1L,SIRT1,GPR161,TGFBR3,HHIP,HEY1,TLR4,HEY2,TNR,TSC1,TSC2,SGK3,UBC,UCHL1,FLRT2,FLRT1,VSNL1,NDRG4,CELF4,MEIS3,PMEPA1,GDPD5,SCG2,PCBP4,WNK2,EPM2A,RGS7BP,PAK5,NLRP3,SOCS4" GO: Biological Process GO:0007015 actin filament organization 5.08E-05 4.98E-01 1.35E-03 1.32E-02 93 345 "ACTN1,ACTN2,ADD1,ADD2,ERMN,PPFIA1,GAS7,SHTN1,SHROOM2,SPTBN4,ARRB1,WASF1,ARHGEF2,CDC42,CFL2,SLIT2,PICK1,BAG4,ARHGEF10,MICAL2,MYADM,SIRPA,DBN1,SHANK1,ABI1,USH1C,FRY,ABI2,SORBS3,TENM1,DMTN,EPS8,PTK2B,DLC1,FER,BAIAP2,MAD2L2,EVL,SORBS1,NCKAP1,IQGAP2,INPP5K,WASF3,ARFIP1,RND1,CIT,GSN,NCKAP1L,SYNPO,SCIN,JAK2,DBNL,PAK3,TMOD2,SSH1,PIK3R1,MAGEL2,PACSIN1,PROX1,GDPD2,RDX,KIRREL1,AP1AR,PPP1R9A,PPM1E,ASAP3,FHOD3,TTC17,SPTAN1,SPTB,CLASP2,KANK1,COBL,TAC1,TACR1,MLST8,CLASP1,FRYL,TF,TMOD1,TPM1,TSC1,TMEFF2,AMOT,PLEKHH2,MICAL1,WIPF1,RICTOR,FMN2,SPIRE1,PCDH15,WIPF2,ACTR3B" GO: Biological Process GO:0035023 regulation of Rho protein signal transduction 5.11E-05 5.02E-01 1.36E-03 1.33E-02 39 115 "ABR,PLEKHG5,ADRA1B,FGD2,ALS2,ARHGDIA,ARRB1,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,CDH2,ADGRG1,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,DLC1,RASGRF1,RASGRF2,ARHGEF10L,ROBO1,ITSN1,PREX2,ARHGEF40,MCF2L2,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" GO: Biological Process GO:0045879 negative regulation of smoothened signaling pathway 5.15E-05 5.05E-01 1.37E-03 1.33E-02 15 29 "PTCH2,CHRD,BTRC,GPR37L1,FGFR3,SALL3,SERPINE2,PRKACB,PTCH1,RFX4,KIF7,SALL1,IFT122,GPR161,HHIP" GO: Biological Process GO:0050801 ion homeostasis 5.24E-05 5.14E-01 1.39E-03 1.35E-02 182 759 "ADCY5,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK1,ANK2,ANK3,ANXA7,GPAM,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCK,CCKBR,RGN,CD38,CLCN3,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,CPS1,ABCG1,DBI,HEPH,FBXL5,KLHL3,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,EGFR,PTK2B,RACK1,FECH,FGF12,FHL1,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNH2,KCNJ10,KCNK3,KCNMA1,SFXN5,AQP11,MT3,MYO5A,NOS1,SLC11A2,HCN1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,RAB39A,SLC26A11,CNNM2,PTH1R,PTK2,PYGM,PPP2R3C,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SCN2B,SCN7A,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SNCA,SCN3B,TAC1,TACR1,TPCN2,ATP13A2,TF,SIRT1,SPX,TRPC1,TRPC3,TRPM2,CA14,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC30A3,WNK1,SLC30A4,TMEM178A,SLC17A7,WNK3,WNK2,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0021681 cerebellar granular layer development 5.33E-05 5.23E-01 1.40E-03 1.37E-02 10 15 "ATP2B2,CBLN1,NRXN1,CEND1,KNDC1,NFIX,SERPINE2,PROX1,FAIM2,WNT7A" GO: Biological Process GO:0021781 glial cell fate commitment 5.33E-05 5.23E-01 1.40E-03 1.37E-02 10 15 "ASCL1,OLIG2,HES5,NKX2-2,PAX6,SOX8,SOX6,SMARCA4,SOX2,TAL1" GO: Biological Process GO:0072583 clathrin-dependent endocytosis 5.55E-05 5.44E-01 1.45E-03 1.42E-02 22 52 "AP2A1,AP2A2,AMPH,SYNJ1,CANX,HIP1R,CLTA,CLTB,DNAJC6,SNAP91,DNM1,TNK2,SMAP1,OPHN1,PACSIN1,ITSN1,SH3GL2,NLGN1,SNCA,FCHO1,SYT1,SYT5" GO: Biological Process GO:0021795 cerebral cortex cell migration 5.55E-05 5.44E-01 1.45E-03 1.42E-02 22 52 "NRP2,CDK5R1,CDK5R2,ADGRG1,SLIT2,CX3CR1,EGFR,FGF13,FGFR1,FOXG1,DISC1,FUT10,MDGA1,MBOAT7,POU3F2,RELN,PEX5,ROBO1,ARX,NR2E1,LRP8,RTN4" GO: Biological Process GO:0023057 negative regulation of signaling 5.94E-05 5.82E-01 1.55E-03 1.51E-02 295 1311 "ASIC1,ACHE,ABHD6,NDRG2,ADAR,AXIN2,BRAP,ADORA1,ADRA1B,ADRB2,BEND6,NLGN4X,AP2A1,AP2A2,AGT,NME5,NR0B1,PLA2G6,C1QTNF3,MRTFA,CNIH2,APC,DGKZ,LRRC4C,MADD,ZFYVE28,ARNTL,ARRB1,RGS20,ARRB2,PDE8B,DACT3,PTCH2,CHRD,NUMB,RASL11B,CCAR2,ATM,RIPK1,BCHE,RGS11,RGS9,BCL2L2,CFLAR,BMP7,ARHGEF7,MTMR2,LDLRAD4,BTRC,CALM1,CAMK2B,CD38,NEURL1,DGKI,ARHGEF2,CDC42,CDH2,NOG,GPR37L1,SOCS6,SLIT2,EPS15L1,CLU,SLC24A2,STOML1,CLTA,MAP4K4,PICK1,ZNF385A,PNKD,CLOCK,CRHBP,CRY2,NCOR1,RGS6,CSNK1E,SOCS5,PHF14,CTH,CTNND1,CX3CR1,GPRASP1,MYADM,ARHGAP24,KIF26A,RASSF2,DAPK1,MAGI2,G3BP2,CHRDL1,DLX1,DMD,DNM1,MED12,DNM2,DRD1,DUSP9,DYRK1A,EDN1,EDN3,HIPK3,HEYL,OPTN,SH3GLB1,EGFR,RASA4,PLEKHA1,RGS17,APC2,EYA1,PTK2B,TAOK3,DLC1,RACK1,FKTN,FGFR3,MAD2L2,AGAP2,FOXM1,FOXO3,STAMBP,DLL3,STAU2,FYN,DKK3,GABBR1,ZMYND11,SALL3,INPP5K,GCK,MSTN,SESN1,PCDH17,GPM6B,GPER1,GRK4,RAPGEF4,GRB10,RAPGEF1,GRIA1,C1QL4,RFFL,GRIK1,GRIK2,GRIK3,NR3C1,GRM5,PTPN5,WIF1,IRAK3,PADI2,HMGCR,HTR2A,IGF1,IGFBP1,NKD1,IL6ST,SCRT2,LRRTM3,LRRTM1,ITGAV,KCNB1,KCNJ11,LRRC4B,SYTL4,PIK3AP1,MAPT,MDFI,SESN3,NBL1,NEUROD1,NF1,NFE2L2,NODAL,NOS1,NUCB2,OPA1,P2RX7,PALM,PDE1C,PDE3B,PDPK1,DUSP26,NLGN3,SERPINE2,NLE1,EPN1,MAPKAP1,STRN3,SH3KBP1,PPM1B,PPP3CA,PRKACB,SKOR1,PRKCB,PRKCZ,MAPK7,PSMA6,PSMD13,PTCH1,PTPRE,CASTOR1,PTPRO,PID1,USP47,RFX4,RGS3,RGS4,RGS7,RGS10,RGS12,KIF7,ROBO1,FBXW7,PRR5L,LRRK2,LGR4,AP1AR,AMER2,SALL1,ATXN1,DRAXIN,ATXN7,LRRTM4,FNIP1,SEC14L1,RASA3,PPP1R9A,SH3GL2,FUZ,ANKRD6,SLC6A1,CDK5RAP3,TRIM67,SHANK2,CXXC4,SMARCA4,SORCS3,IFT122,SNCA,FAIM2,LMBRD1,SOX2,SOX10,HECW1,UNC5B,PEG10,IQSEC2,SPART,LMO3,PBLD,MESP1,LRRC4,ERBIN,KANK1,SULF2,STXBP1,SYT11,ABCC8,TAF9,WWC1,FBXW11,MGRN1,VWC2,TCF7L2,RPGRIP1L,SIRT1,GPR161,TGFBR3,HHIP,HEY1,TLR4,HEY2,TNR,TSC1,TSC2,SGK3,UBC,UCHL1,FLRT2,FLRT1,VSNL1,NDRG4,CELF4,MEIS3,PMEPA1,GDPD5,SCG2,PCBP4,WNK2,EPM2A,RGS7BP,PAK5,NLRP3,SOCS4" GO: Biological Process GO:0030010 establishment of cell polarity 6.40E-05 6.28E-01 1.67E-03 1.63E-02 40 120 "SHTN1,BRSK2,KRIT1,ARHGEF2,PARD6A,DOCK2,WDPCP,EPHB1,EYA1,PTK2B,RACK1,FGF13,BRSK1,GSN,DOCK7,HES5,MAP2,MAP4,NUMA1,PAX6,PKD1,GPSM2,PRKCZ,BCAS3,LAMA1,PTK2,SPDL1,FERMT1,MYO18A,CDK5RAP2,KANK1,WWC1,CLASP1,HEY1,PARD3,AMOT,WNT7A,RICTOR,SNX27,VANGL2" GO: Biological Process GO:0030003 cellular cation homeostasis 7.02E-05 6.88E-01 1.82E-03 1.78E-02 146 592 "ADCY5,ADCYAP1R1,SLC12A5,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,CLCN3,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,DBI,HEPH,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,PTK2B,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,KCNMA1,AQP11,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,RAB39A,SLC26A11,PTH1R,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,TRPC1,TRPC3,TRPM2,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0086012 membrane depolarization during cardiac muscle cell action potential 7.13E-05 7.00E-01 1.85E-03 1.80E-02 11 18 "ANK2,ANK3,ATP1A2,CACNA1G,CACNA1D,CACNA2D1,CACNB2,SCN2B,SCN4B,SLC8A1,SCN3B" GO: Biological Process GO:0055080 cation homeostasis 7.15E-05 7.01E-01 1.85E-03 1.80E-02 165 682 "ADCY5,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK1,ANK2,ANK3,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,CLCN3,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,DBI,HEPH,FBXL5,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,EGFR,PTK2B,FECH,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNH2,KCNJ10,KCNK3,KCNMA1,SFXN5,AQP11,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,RAB39A,SLC26A11,CNNM2,PTH1R,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SCN7A,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,SPX,TRPC1,TRPC3,TRPM2,CA14,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:1901880 negative regulation of protein depolymerization 7.23E-05 7.09E-01 1.86E-03 1.81E-02 26 67 "ADD1,ADD2,APC,SHROOM2,SPTBN4,ARHGEF2,DMTN,EPS8,APC2,FGF13,EVL,EML4,STMN2,GSN,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SPTAN1,SPTB,CLASP2,CLASP1,TMOD1,PLEKHH2" GO: Biological Process GO:0007632 visual behavior 7.23E-05 7.09E-01 1.86E-03 1.81E-02 26 67 "ADRA1B,APBB1,APP,PDE8B,ATP1A2,ATP1A3,CACNA1E,NOG,CHRNB2,DRD1,PPP1R1B,NPTN,GRIN1,HMGCR,KIT,MEIS2,NF1,PDE1B,NLGN3,PTPRZ1,ATXN1,SGK1,SLC1A2,DDHD2,NDRG4,NETO1" GO: Biological Process GO:0051954 positive regulation of amine transport 7.54E-05 7.39E-01 1.93E-03 1.89E-02 20 46 "ABAT,ADORA2A,AGT,CCK,CHRNA4,CHRNB2,DPYSL2,GABBR1,GRIK1,NR3C1,KCNB1,NAT8L,OXTR,P2RX7,PLCD1,SLC6A1,RAB3GAP1,STX1A,TRH,RTN4" GO: Biological Process GO:0060491 regulation of cell projection assembly 7.59E-05 7.45E-01 1.94E-03 1.89E-02 53 174 "TBC1D14,APC,HAP1,NEURL1,SEPT7,CDC42,EVI5L,SLIT2,NRXN1,CCDC151,PPP1R16B,USP6NL,ARHGAP24,HDAC4,TBC1D5,DBN1,DNM2,WDPCP,TENM1,DMTN,SH3YL1,TBC1D16,FER,EVL,STAU2,NCKAP1,GAP43,SEPT9,GPM6A,HSP90AA1,KIT,MAP4,ODF2,P2RX7,PALM,SSH1,PLXNB3,BCAS3,CEP97,RAP1GAP,RDX,KCTD17,PPP1R9A,FUZ,NLGN1,TTBK2,KANK1,COBL,ZMYND8,TBC1D15,PLPPR5,EVI5,IFT88" GO: Biological Process GO:0021846 cell proliferation in forebrain 8.01E-05 7.85E-01 2.04E-03 1.99E-02 16 33 "NUMB,NUMBL,NCOR2,DCT,ZEB2,EMX2,FABP7,FGFR1,TACC2,DISC1,DOCK7,PAX6,POU3F2,ARX,TACC1,WNT7A" GO: Biological Process GO:0060080 inhibitory postsynaptic potential 8.29E-05 8.13E-01 2.10E-03 2.05E-02 12 21 "ABAT,ADORA2A,CHRNA4,RIMS2,DBN1,GABRB3,GRIK1,GRIK2,NLGN3,NLGN1,IGSF9B,RIMS1" GO: Biological Process GO:2000311 regulation of AMPA receptor activity 8.29E-05 8.13E-01 2.10E-03 2.05E-02 12 21 "CNIH2,NRXN1,CNIH3,SHANK1,CACNG7,CACNG3,CACNG2,MEF2C,NLGN3,RELN,NLGN1,ARC" GO: Biological Process GO:0014048 regulation of glutamate secretion 8.29E-05 8.13E-01 2.10E-03 2.05E-02 12 21 "ADORA1,ADORA2A,CCK,DPYSL2,GABBR1,NR3C1,GRM7,HRH3,P2RX7,RAB3GAP1,SNCA,TRH" GO: Biological Process GO:0010770 positive regulation of cell morphogenesis involved in differentiation 8.39E-05 8.23E-01 2.12E-03 2.07E-02 55 183 "ACHE,AXIN2,SEMA7A,EPB41L5,SHTN1,ARHGDIA,CAPRIN2,NUMB,ARHGEF7,KALRN,CAMK2B,CDC42,NUMBL,SLIT2,AKAP5,MYADM,IST1,DBN1,ZEB2,DNM2,DSCAM,EIF4G2,DMTN,CDKL3,OLFM1,BAIAP2,SEMA4D,STAU2,DISC1,GCNT2,IL1RAPL1,HAS2,ITPKA,L1CAM,LIMS1,MAPT,NTRK2,NTRK3,PAK3,ENPP2,PLXNB1,PLXNB3,MAPK9,RELN,PTPRD,ROBO1,ROBO2,SGK1,CUX2,TCF7L2,OBSL1,TIAM1,BHLHB9,CRB2,LRP8" GO: Biological Process GO:0048710 regulation of astrocyte differentiation 8.55E-05 8.39E-01 2.15E-03 2.10E-02 15 30 "BIN1,NOG,GPR37L1,FGFR3,DLL3,HES5,IL6ST,MAG,MBD1,MYCN,NF1,NTRK3,SERPINE2,CNTN2,NR2E1" GO: Biological Process GO:0043268 positive regulation of potassium ion transport 8.70E-05 8.53E-01 2.18E-03 2.13E-02 19 43 "ACTN2,ADORA1,ADRB2,ANK2,ATP1B3,AKAP7,AKAP6,NOS1AP,DNM2,DPP6,DRD1,EDN3,FHL1,KCNC1,KCNC2,KCNH2,NPPA,ABCC8,KCNE5" GO: Biological Process GO:0051402 neuron apoptotic process 9.05E-05 8.88E-01 2.27E-03 2.21E-02 73 261 "ADORA2A,AGT,APAF1,APP,ASCL1,ATM,BID,CDK5R1,NAE1,CACNA1A,AIFM1,CDC42,CRLF1,CNTFR,AATK,HDAC4,DLX1,ATN1,OPTN,EN2,PTK2B,FGFR3,AGAP2,FOXO3,STAMBP,FYN,GABRA5,CHL1,GABRB3,ZNF274,PPARGC1A,TOX3,KDM2B,GRIK2,GRIK5,GRIN1,NR3C1,JAK2,KCNB1,KCNMA1,LIG4,MEF2C,NRBP2,MT3,NCF2,NF1,NTRK2,PAK3,PDPK1,RETREG1,PPP2R2B,VSTM2L,PRKCG,MAPK8,OXR1,FBXW7,KCNIP3,DRAXIN,SCN2A,ITSN1,AMBRA1,CPEB4,SNCB,SNCA,FAIM2,UNC5B,SRPK2,STXBP1,TRIM2,SIRT1,BHLHB9,XRCC4,MAP3K12" GO: Biological Process GO:0008154 actin polymerization or depolymerization 9.15E-05 8.98E-01 2.28E-03 2.23E-02 57 192 "ACTN2,ADD1,ADD2,GAS7,SHROOM2,SPTBN4,WASF1,CFL2,SLIT2,PICK1,BAG4,MICAL2,MYADM,DBN1,ABI1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,WASF3,ARFIP1,CIT,GSN,NCKAP1L,SCIN,JAK2,DBNL,PAK3,TMOD2,SSH1,MAGEL2,RDX,KIRREL1,AP1AR,PPP1R9A,FHOD3,TTC17,SPTAN1,SPTB,KANK1,COBL,MLST8,TMOD1,PLEKHH2,MICAL1,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Biological Process GO:0048870 cell motility 9.22E-05 9.04E-01 2.29E-03 2.24E-02 317 1428 "ABR,ABHD6,PLEKHG5,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,MRTFA,CDC42BPA,SEMA7A,APBB1,APBB2,APC,EPB41L5,DGKZ,SHTN1,SHROOM2,SEMA4G,ARHGAP5,ARHGDIA,ARRB2,ASCL1,DNAH17,CHRD,NUMB,ASTN1,ATP1B3,ADAM15,BBS2,NRP2,CDK5R1,DST,ARHGEF7,CACNA1I,C5,CDK5R2,IL33,LDLRAD4,CACNA1E,DDR1,LURAP1,CAMK2D,SPAG9,CCK,LDB2,KRIT1,FMNL3,RGN,SCARB1,NEURL1,CD81,CDC42,CDH2,DCLK1,NOG,ADGRG1,CHGA,JAM2,TAOK2,SLIT2,BAG4,NRG2,CDC42BPB,CSF1,CSF1R,CSF3R,VCAN,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,ARHGAP24,HDAC4,DAPK3,SIRPA,DCC,ZEB2,ELMO1,KIAA0319,MAGI2,SRGAP3,DRD1,WDPCP,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,CELSR3,EGFR,ABI2,EGR3,PLXNC1,IRAK4,TNK2,EMX2,PLEKHO1,DMTN,EPHB1,EPS8,ERBB2,ERBB4,APC2,CEND1,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FKTN,FER,FGF1,OLFM1,FGF13,FGFR1,FGR,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,NRG3,FYN,GAB1,CHL1,NCKAP1,DISC1,DNER,GBX2,GCNT2,GFRA1,PPARGC1A,KIRREL3,GPM6A,FUT10,GPER1,RAPGEF4,RFFL,GSN,BVES,RABL2A,ATOH8,CELF3,HAS2,PADI2,NCKAP1L,HMGB1,HSP90AA1,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INPP5B,INSM1,TUBB2B,ITGA7,ITGAM,ITGAV,JAK1,JAK2,KIT,L1CAM,LAMA2,MAG,MAPT,MARK1,MATK,MATN2,MEF2C,KITLG,MITF,CCDC80,MDGA1,NACA,NBL1,NF1,NFE2L2,NODAL,NRCAM,NRDC,NTRK2,NTRK3,DDR2,OGDH,OLR1,OPHN1,P2RY1,PAK3,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,ANLN,PIK3CD,PIK3R1,PLTP,PLXNB1,PLXNB3,SCHIP1,MBOAT7,EPB41L4B,FAT3,SH3KBP1,POU3F2,PKN2,PRKCZ,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,CCDC40,FEZF2,RDX,RET,RFX3,ROBO1,FBXW7,PRR5L,LRRK2,SOX8,AP1AR,SEMA6D,SELL,SGK1,ARX,FERMT1,ASAP3,MYO18A,DOCK10,FUZ,SLC8A1,CCDC88A,ELMO2,SLIT1,SMARCA4,PALLD,USP33,SOX1,SOX10,SPP1,PBLD,CLASP2,MESP1,SST,KANK1,SYNE2,PLCB1,ARC,TAC1,TACR1,SEMA4A,ROBO3,UNC5D,CNTN2,ADGRL3,WWC1,SATB2,CLASP1,TEK,TF,DNAH7,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,PARD3,TNR,TNS1,RBFOX2,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,VAV1,VAV2,P2RY12,WNT7A,NDRG4,ZFAND5,LRP8,SCG2,SEMA3B,FZD3,DOCK8,RTN4,PAK5,VANGL2,SPATA13" GO: Biological Process GO:0051674 localization of cell 9.22E-05 9.04E-01 2.29E-03 2.24E-02 317 1428 "ABR,ABHD6,PLEKHG5,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,MRTFA,CDC42BPA,SEMA7A,APBB1,APBB2,APC,EPB41L5,DGKZ,SHTN1,SHROOM2,SEMA4G,ARHGAP5,ARHGDIA,ARRB2,ASCL1,DNAH17,CHRD,NUMB,ASTN1,ATP1B3,ADAM15,BBS2,NRP2,CDK5R1,DST,ARHGEF7,CACNA1I,C5,CDK5R2,IL33,LDLRAD4,CACNA1E,DDR1,LURAP1,CAMK2D,SPAG9,CCK,LDB2,KRIT1,FMNL3,RGN,SCARB1,NEURL1,CD81,CDC42,CDH2,DCLK1,NOG,ADGRG1,CHGA,JAM2,TAOK2,SLIT2,BAG4,NRG2,CDC42BPB,CSF1,CSF1R,CSF3R,VCAN,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,ARHGAP24,HDAC4,DAPK3,SIRPA,DCC,ZEB2,ELMO1,KIAA0319,MAGI2,SRGAP3,DRD1,WDPCP,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,CELSR3,EGFR,ABI2,EGR3,PLXNC1,IRAK4,TNK2,EMX2,PLEKHO1,DMTN,EPHB1,EPS8,ERBB2,ERBB4,APC2,CEND1,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FKTN,FER,FGF1,OLFM1,FGF13,FGFR1,FGR,FOXG1,SEMA6C,EVL,SEMA4D,FLT1,FOLR2,NRG3,FYN,GAB1,CHL1,NCKAP1,DISC1,DNER,GBX2,GCNT2,GFRA1,PPARGC1A,KIRREL3,GPM6A,FUT10,GPER1,RAPGEF4,RFFL,GSN,BVES,RABL2A,ATOH8,CELF3,HAS2,PADI2,NCKAP1L,HMGB1,HSP90AA1,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INPP5B,INSM1,TUBB2B,ITGA7,ITGAM,ITGAV,JAK1,JAK2,KIT,L1CAM,LAMA2,MAG,MAPT,MARK1,MATK,MATN2,MEF2C,KITLG,MITF,CCDC80,MDGA1,NACA,NBL1,NF1,NFE2L2,NODAL,NRCAM,NRDC,NTRK2,NTRK3,DDR2,OGDH,OLR1,OPHN1,P2RY1,PAK3,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,ANLN,PIK3CD,PIK3R1,PLTP,PLXNB1,PLXNB3,SCHIP1,MBOAT7,EPB41L4B,FAT3,SH3KBP1,POU3F2,PKN2,PRKCZ,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PEX2,PEX5,CCDC40,FEZF2,RDX,RET,RFX3,ROBO1,FBXW7,PRR5L,LRRK2,SOX8,AP1AR,SEMA6D,SELL,SGK1,ARX,FERMT1,ASAP3,MYO18A,DOCK10,FUZ,SLC8A1,CCDC88A,ELMO2,SLIT1,SMARCA4,PALLD,USP33,SOX1,SOX10,SPP1,PBLD,CLASP2,MESP1,SST,KANK1,SYNE2,PLCB1,ARC,TAC1,TACR1,SEMA4A,ROBO3,UNC5D,CNTN2,ADGRL3,WWC1,SATB2,CLASP1,TEK,TF,DNAH7,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,PARD3,TNR,TNS1,RBFOX2,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,VAV1,VAV2,P2RY12,WNT7A,NDRG4,ZFAND5,LRP8,SCG2,SEMA3B,FZD3,DOCK8,RTN4,PAK5,VANGL2,SPATA13" GO: Biological Process GO:0033674 positive regulation of kinase activity 9.64E-05 9.46E-01 2.39E-03 2.33E-02 132 530 "ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADRB2,KIDINS220,AGT,OSBPL8,TAOK1,ALK,FGD2,MAP4K3,ALS2,MADD,ARRB1,RIPK1,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,SPAG9,CCNH,CCNT1,NEURL1,CD81,CDC25B,CDC42,TAOK2,CLU,AKAP6,MAGED1,CSF1,CSF1R,RASSF2,ZEB2,ABI1,DUSP9,EDN1,EDN3,EEF1A2,RASGRP1,SH3GLB1,EGFR,TENM1,ERBB2,ERBB4,PTK2B,TAOK3,STRADA,FGF1,FGF13,FGFR1,FGFR3,FGR,PRKAG2,AGAP2,FLT1,CAMKK2,NRG3,GAB1,CAB39,GHR,MALT1,COPS8,GNG3,PSRC1,RAPGEF1,GRM1,GRM5,MAP4K5,NCKAP1L,TNFAIP8L3,HMGB1,HTR2A,IGF1,IL6R,JAK2,KIT,MDFI,KITLG,DBNL,MT3,NELL1,NTRK3,DDR2,P2RX7,PAK3,PDGFRA,PDPK1,PFKFB2,PKD1,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK10,DIRAS2,PROX1,RELN,PTK2,PPP2R3C,FBXW7,LRRK2,PPP1R9A,MAGI3,AMBRA1,CCDC88A,SLC11A1,MAPKBP1,SNCA,TNIK,TAB2,STOX1,MAPK8IP3,FGD4,TEK,TF,SIRT1,TIAM1,TLR4,ZFP91,PIK3R5,UBC,VAV2,VLDLR,MAP3K12,LRP8,VANGL2" GO: Biological Process GO:0019722 calcium-mediated signaling 9.82E-05 9.63E-01 2.43E-03 2.37E-02 50 163 "ADORA3,ANK2,ASPH,ATP1A2,ATP2A2,BTK,CACNA1D,CALM1,HAP1,CAMK2D,RGN,AKAP6,HDAC4,DMD,DMPK,DRD1,RCAN1,FIS1,EDN1,EGFR,RCAN2,DMTN,NCALD,PTK2B,CAMKK2,JPH4,TOX3,GRM1,PTGDR2,HPCA,IGF1,L1CAM,MYO5A,NCAM1,NEUROD2,NOS1,NTRK2,KSR2,TREM2,PDE4D,PDPK1,PPP3CA,PPP3CB,TMEM100,LRRK2,PPP1R9A,SLC8A1,TPCN2,LAT2,JPH3" GO: Biological Process GO:1901879 regulation of protein depolymerization 9.86E-05 9.67E-01 2.43E-03 2.37E-02 30 83 "ACTN2,ADD1,ADD2,APC,SHROOM2,SPTBN4,ASPH,ARHGEF2,CFL2,DMTN,EPS8,APC2,FGF13,EVL,EML4,STMN2,GSN,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SLN,SPTAN1,SPTB,CLASP2,CLASP1,TMOD1,PLEKHH2" GO: Biological Process GO:0070588 calcium ion transmembrane transport 1.06E-04 1.00E+00 2.60E-03 2.54E-02 75 271 "ASIC1,SLC25A25,SLC24A4,PLA2G6,ANK2,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2D,CAPN3,RGN,CACNA2D2,CBARP,SLC24A2,AKAP6,NOS1AP,DBI,GRIN3A,DMD,DRD1,EDNRA,CACNG7,CACNG3,CACNG2,PTK2B,FGF14,ATP2C1,JPH4,GPM6A,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,ITGAV,MYO5A,NOS1,NPPA,OPRL1,P2RX7,PDE2A,PDE4B,PDE4D,PDPK1,PKD1,RYR1,RYR3,RASA3,SLC8A2,SLC8A1,SLC8A3,SLN,SNCA,TPCN2,TRPC1,TRPC3,TRPM2,P2RY12,JPH3" GO: Biological Process GO:0051270 regulation of cellular component movement 1.06E-04 1.00E+00 2.61E-03 2.55E-02 201 860 "ABR,ABHD6,ACTN1,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,ANK2,SEMA7A,CNIH2,APC,EPB41L5,SHTN1,SEMA4G,ARHGAP5,ARHGDIA,CHRD,NUMB,ATP1A1,ATP1A2,ATP2A2,ADAM15,BBS2,NRP2,ARHGEF7,C5,IL33,LDLRAD4,HAP1,CAMK2D,SPAG9,LDB2,KRIT1,RGN,SCARB1,CD81,NOG,ADGRG1,SLIT2,AKAP6,BAG4,NRG2,CSF1,CSF1R,PLXNA4,SDC3,CX3CR1,NOS1AP,DOCK4,HDAC9,MYADM,TCAF1,HDAC4,DAPK3,DBN1,MAGI2,SRGAP3,DRD1,DSCAM,WDPCP,EDN1,EDN3,EDNRA,SEMA3D,EGFR,PLXNC1,DMTN,ERBB2,ERBB4,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FER,FGF1,OLFM1,FGFR1,FGR,SEMA6C,EVL,SEMA4D,FLT1,TBR1,NRG3,GAB1,GCNT2,PPARGC1A,GPER1,RAPGEF4,RFFL,GSN,KIF3A,ATOH8,HAS2,PADI2,NCKAP1L,HMGB1,MYLK2,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INSM1,ITGAV,JAK2,KIT,LAMA2,STMN1,MAPT,KITLG,CTNNA3,NBL1,NEFH,NF1,NFE2L2,NODAL,NTRK3,DDR2,PAK3,PAX6,PDE4B,PDE4D,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,PIK3CD,PIK3R1,FXYD1,PLXNB1,PLXNB3,EPB41L4B,PKN2,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,CCDC40,FEZF2,RDX,RET,ROBO1,FBXW7,PRR5L,AP1AR,SEMA6D,SELL,SGK1,DOCK10,FUZ,SLC8A1,SLIT1,SMARCA4,PBLD,CLASP2,SST,KANK1,SYNE2,PLCB1,TAC1,TACR1,SEMA4A,UNC5D,CLASP1,TEK,TF,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,P2RY12,WNT7A,NDRG4,SEMA3B,RTN4,SPATA13" GO: Biological Process GO:0009914 hormone transport 1.11E-04 1.00E+00 2.72E-03 2.66E-02 97 370 "ABAT,ADCY5,ADORA1,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,BTK,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,CRY2,CRYM,RIMS2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,EPHA5,FGFR1,OGA,GABBR1,ILDR2,GALR1,CPLX1,GCK,GDF9,GLUL,GNAS,GPER1,PCLO,RAPGEF4,HMGCR,HTR2A,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYO5A,MYT1,NELL2,NEUROD1,SLCO1C1,NNAT,NOS1,NUCB2,P2RY1,PAX6,PDE1C,PDE3B,PFKFB2,ABCB1,PPP3CA,PPP3CB,PTPRN,PTPRN2,RFX3,SMPD3,SCG5,SYBU,SLCO1A2,SNAP25,SOX11,STX1A,ABCC8,TAC1,TACR1,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:0071867 response to monoamine 1.13E-04 1.00E+00 2.74E-03 2.68E-02 17 37 "ADCY6,ADRB2,APLP1,APP,AKAP6,DNM2,DRD1,PPARGC1A,GNAS,NOS1,PDE4B,PDE4D,GNG2,PENK,LRRK2,SIRT2,SNCA" GO: Biological Process GO:0055074 calcium ion homeostasis 1.13E-04 1.00E+00 2.75E-03 2.68E-02 109 425 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,AKAP6,SLC25A27,AKAP5,DBI,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,PTK2B,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,MYO5A,NOS1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SMPD3,RASA3,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,TMEM178A,JPH3" GO: Biological Process GO:0006171 cAMP biosynthetic process 1.17E-04 1.00E+00 2.85E-03 2.78E-02 41 127 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,APLP1,CALM1,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,CAP2,GABBR1,GALR1,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A1,GUCY1B1,HRH3,HPCA,P2RY13,NF1,NUCB2,OPRL1,PALM,PDE2A,PTHLH,MRAP2,GPR161,VIPR2" GO: Biological Process GO:0048712 negative regulation of astrocyte differentiation 1.19E-04 1.00E+00 2.86E-03 2.79E-02 10 16 "NOG,GPR37L1,FGFR3,DLL3,HES5,MBD1,MYCN,NF1,NTRK3,NR2E1" GO: Biological Process GO:0021889 olfactory bulb interneuron differentiation 1.19E-04 1.00E+00 2.86E-03 2.79E-02 10 16 "SLIT2,ERBB4,FGFR1,SALL3,ROBO1,ROBO2,SALL1,ARX,SLIT1,DICER1" GO: Biological Process GO:0014051 gamma-aminobutyric acid secretion 1.19E-04 1.00E+00 2.86E-03 2.79E-02 10 16 "ABAT,CACNA1A,CACNB4,GABBR1,GRIK1,HRH3,NF1,P2RX7,SLC6A1,TRH" GO: Biological Process GO:0048863 stem cell differentiation 1.19E-04 1.00E+00 2.86E-03 2.79E-02 82 303 "AXIN2,AP2A2,SEMA6A,SEMA7A,EPB41L5,SEMA4G,ASCL1,DACT3,ADAM15,BCHE,NRP2,BMP7,LDLRAD4,NOG,PUM1,ECE2,PHF19,ZEB2,EDN1,EDN3,EDNRA,EDNRB,HEYL,SEMA3D,ERBB4,ERCC2,OLFM1,FGFR1,MAD2L2,FOXF2,SEMA6C,SEMA4D,GBX2,GCNT2,MSTN,KDM2B,LOXL3,GPM6A,SOX21,HAS2,RBPJ,HES5,KIT,LIMS1,MEF2C,KITLG,NFE2L2,NFYA,NODAL,PAX6,PDGFRA,SEMA5B,MAPK3,RET,TMEM100,SOX8,SEMA6D,SOX6,FUZ,SHC4,SOX2,SOX5,SOX10,SOX11,KDM3A,KDM4C,PBLD,CLASP2,PHLDB1,SEMA4A,TAL1,TCF7L2,CLASP1,DICER1,TGFBR3,HEY1,HEY2,WNT7A,CRB2,SEMA3B,RTN4,VANGL2" GO: Biological Process GO:0052652 cyclic purine nucleotide metabolic process 1.23E-04 1.00E+00 2.96E-03 2.89E-02 48 156 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,AMPD2,APLP1,CALM1,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,CAP2,GABBR1,GALR1,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,HPCA,P2RY13,NF1,NOS1,NPPA,NPR2,NUCB2,OPRL1,PALM,PDE2A,PTHLH,MRAP2,GPR161,VIPR2" GO: Biological Process GO:0048878 chemical homeostasis 1.24E-04 1.00E+00 2.98E-03 2.91E-02 257 1136 "ACADM,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRA1D,ADRA1B,SLC24A4,AGT,DISP3,PLA2G6,C1QTNF1,ADGRF5,C1QTNF3,SPOP,AMPD2,OGT,ANK1,ANK2,ANK3,ANXA7,GPAM,APOC2,APP,AQP4,AQP6,ARRB1,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA1E,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,BRSK2,CCK,CCKBR,RGN,SCARB1,CD38,SOCS6,CLCN3,NRXN1,SLC24A2,ABCG2,MAP4K4,CNR1,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,CPS1,CRY2,NCOR1,NCOR2,ABCG1,DBI,HEPH,FBXL5,C2CD2L,KLHL3,SV2A,DLG4,DMD,DMPK,NR1D2,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,SIDT2,EGFR,EPHA5,ERBB4,PTK2B,RACK1,FECH,FGF12,FHL1,RGPD5,FOXO3,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,INPP5K,GCK,PPARGC1A,GK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIK5,GRIN1,GRM1,HAS2,HRH3,HMGB1,HMGCR,HNRNPK,HTR2A,IGF1,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNB1,KCNH2,KCNJ10,KCNJ11,KCNK3,KCNMA1,SFXN5,AQP11,SESN3,MT3,MTTP,MYO5A,MYT1,NEUROD1,NOS1,SLC11A2,HCN1,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PAX6,PDE3B,PDE4D,PDGFRA,PDPK1,PIK3R1,PKD1,PLCD1,FXYD1,SLC25A23,POLG,PPP3CA,PPP3CB,PRKACB,PRKAR1B,PRKCB,RAB39A,SLC26A11,FITM2,CNNM2,PTCH1,PTHLH,PTH1R,PTK2,PTPRN,PTPRN2,PEX2,PYGM,PPP2R3C,RAP1GDS1,KCTD17,FBXW7,LRRK2,RYR1,RYR3,RMI1,S100B,SCN2B,SCN7A,SMPD3,SLC30A10,RASA3,SGK1,HKDC1,SYBU,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SMARCA4,SNCA,MBD5,SCN3B,WDTC1,STAU1,APOM,TAC1,TACR1,TCF7L2,TPCN2,ATP13A2,TF,SIRT1,SPX,TIAM1,CSMD1,STXBP4,TRPC1,TRPC3,TRPM2,CA14,TTPA,SGK3,UBTF,VGF,VSNL1,ATP6V0E2,SLC26A10,SLC30A3,WNK1,SLC30A4,TMEM178A,SLC17A7,WNK3,WNK2,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0016601 Rac protein signal transduction 1.26E-04 1.00E+00 3.00E-03 2.93E-02 16 34 "HACE1,OGT,ALS2,WASF1,CAMK2D,ARHGAP24,ELMO1,DNM2,DOCK2,ABI2,EPS8,NCKAP1,DBNL,NF1,RASGRF1,TIAM1" GO: Biological Process GO:0014824 artery smooth muscle contraction 1.26E-04 1.00E+00 3.01E-03 2.94E-02 8 11 "AGT,BBS2,CACNA1G,EDN1,EDN3,EDNRA,HTR2A,SMPD3" GO: Biological Process GO:0002209 behavioral defense response 1.27E-04 1.00E+00 3.01E-03 2.94E-02 19 44 "ALS2,PDE8B,CACNA1E,KALRN,CCK,CCKBR,BRINP1,DBI,LYPD1,DRD1,EIF4G1,GABRA5,GRIK2,GRM7,MEF2C,NEUROD2,PENK,ANKFN1,NR2E1" GO: Biological Process GO:0072657 protein localization to membrane 1.34E-04 1.00E+00 3.18E-03 3.11E-02 128 515 "SYS1,ACTN2,ADCY6,ADORA1,GPR158,OSBPL8,OGT,DPP10,ANK1,ANK2,ANK3,PPFIA1,SPTBN4,NUMB,DYNLL1,ATP1B3,BBS2,BID,CDK5R1,RAB29,CACNA1A,CACNB2,KALRN,CAPN3,MAP7,CDH2,CHM,TAOK2,NRXN1,NRXN2,CLTC,HECTD1,RAB26,PICK1,BAG4,CLIP3,APPL1,MYADM,TCAF1,DBN1,MAGI2,DLG2,DLG3,DLG4,DPP6,FIS1,TSPAN5,OPTN,SH3GLB1,EGFR,GOLGA7,DMTN,GPHN,ERBB2,REEP2,RACK1,FGF13,VTI1B,FOLR2,SORBS1,OGA,FYB1,RAPGEF6,INPP5K,GLRB,FERMT2,GPER1,GRIK2,GRIK5,GSN,ATG4C,HPCA,HSP90AA1,KCNB1,ZFYVE27,LYPLAL1,MYO5A,P2RY1,ZDHHC22,TREM2,PALM,PDPK1,PIK3R1,PACSIN1,PPP3CC,PRKCZ,MAPK8,RELN,SYTL2,PTCH1,PTN,PEX5,PID1,RDX,RPL15,RPL38,RPS20,KCNIP3,CLIP1,LRRTM4,SCP2,NLGN1,PEX26,RAB3GAP1,RTP5,IFT122,KIF13A,SCN3B,TNIK,NFASC,CLASP2,EPB41L3,LRRC4,STXBP1,ARHGEF9,MTCL1,TIAM1,PARD3,TP53BP2,ZMYND8,TSC2,RFTN2,TUB,REEP1,MFF,WNK3,GOPC,TTC7A" GO: Biological Process GO:0014031 mesenchymal cell development 1.35E-04 1.00E+00 3.19E-03 3.12E-02 55 186 "AXIN2,SEMA6A,SEMA7A,EPB41L5,SEMA4G,DACT3,ADAM15,NRP2,BMP7,LDLRAD4,NOG,ZEB2,EDN1,EDN3,EDNRA,EDNRB,HEYL,SEMA3D,ERBB4,OLFM1,MAD2L2,FOXF2,SEMA6C,SEMA4D,GBX2,GCNT2,LOXL3,HAS2,RBPJ,LIMS1,KITLG,PAX6,SEMA5B,MAPK3,RET,TMEM100,SOX8,SEMA6D,FUZ,SOX10,SOX11,PBLD,CLASP2,PHLDB1,SEMA4A,TCF7L2,CLASP1,DICER1,TGFBR3,HEY1,HEY2,CRB2,SEMA3B,RTN4,VANGL2" GO: Biological Process GO:0070838 divalent metal ion transport 1.41E-04 1.00E+00 3.33E-03 3.25E-02 115 455 "ASIC1,SLC25A25,ADCYAP1R1,ADORA2A,ADRB2,SLC24A4,AGT,PLA2G6,ANK2,CACHD1,CASK,ARRB2,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,RGN,CACNA2D2,CBARP,CHRNA4,CHRNB2,SLC24A2,AKAP6,AKAP5,NOS1AP,DBI,GRIN3A,DMD,DRD1,EDNRA,CACNG7,CALCRL,CACNG3,CACNG2,PTK2B,FGF14,ATP2C1,SARAF,OGA,FYN,JPH4,INPP5K,GCK,GNAO1,GPM6A,MCHR1,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,IGF1,ITGAV,SLC35G1,MT3,MYO5A,NOS1,NPY,NPPA,SLC11A2,OPRL1,P2RX7,PDE2A,PDE4B,PDE4D,PDPK1,NALCN,PIK3C2A,PKD1,PPP3CA,PRKCB,CNNM2,RYR1,RYR3,SLC30A10,RASA3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SLN,SNCA,TPCN2,TF,TRPC1,TRPC3,TRPM2,BEST1,P2RY12,SLC30A3,SLC30A4,WNK3,SLC39A12,JPH3" GO: Biological Process GO:2001257 regulation of cation channel activity 1.42E-04 1.00E+00 3.35E-03 3.27E-02 34 100 "ASIC2,ACTN2,PLA2G6,ANK2,ANK3,ASPH,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,CBARP,STOML1,AKAP7,AKAP6,NOS1AP,DMD,FGF12,FGF14,JPH4,KCNJ11,MYO5A,NOS1,NPPA,HCN1,OPRL1,PDE4B,PDE4D,PIRT,KCNIP2,KCNE5,KCNAB1,JPH3" GO: Biological Process GO:0009190 cyclic nucleotide biosynthetic process 1.46E-04 1.00E+00 3.43E-03 3.35E-02 48 157 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,AMPD2,APLP1,CALM1,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,CAP2,GABBR1,GALR1,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,HPCA,P2RY13,NF1,NOS1,NPPA,NPR2,NUCB2,OPRL1,PALM,PDE2A,PTHLH,MRAP2,GPR161,VIPR2" GO: Biological Process GO:0042220 response to cocaine 1.51E-04 1.00E+00 3.54E-03 3.45E-02 22 55 "ABAT,ADRA1B,KALRN,CHRNB2,CNR1,CRHBP,DLG4,DNM2,DPYSL2,DRD1,PTK2B,HNMT,HTR2A,MBD1,NCAM1,NEFH,NOS1,OXTR,SLC6A1,SNCA,ADGRL3,TIAM1" GO: Biological Process GO:0051957 positive regulation of amino acid transport 1.52E-04 1.00E+00 3.54E-03 3.45E-02 12 22 "ABAT,ADORA2A,AGT,CCK,DPYSL2,GABBR1,GRIK1,NR3C1,P2RX7,SLC6A1,RAB3GAP1,TRH" GO: Biological Process GO:0051258 protein polymerization 1.52E-04 1.00E+00 3.54E-03 3.45E-02 68 243 "ADD1,ADD2,APC,GAS7,SPTBN4,WASF1,SLIT2,PICK1,BAG4,GDA,CLIP3,MYADM,DBN1,DNM1L,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,FGF13,BAIAP2,EVL,TPPP3,NCKAP1,IQGAP2,WASF3,TUBGCP4,ARFIP1,PSRC1,STMN2,TPPP,GSN,NCKAP1L,SCIN,JAK2,STMN1,MAPT,DBNL,BLOC1S2,PAK3,TMOD2,MAGEL2,MAPK8,RDX,KIRREL1,CLIP1,AP1AR,SGK1,PPP1R9A,FHOD3,TTC17,SNCA,SPTAN1,SPTB,CLASP2,KANK1,COBL,MLST8,CLASP1,TMOD1,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B,SLC39A12" GO: Biological Process GO:0006816 calcium ion transport 1.52E-04 1.00E+00 3.54E-03 3.45E-02 104 405 "ASIC1,SLC25A25,ADCYAP1R1,ADORA2A,ADRB2,SLC24A4,AGT,PLA2G6,ANK2,CACHD1,CASK,ARRB2,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,RGN,CACNA2D2,CBARP,CHRNA4,CHRNB2,SLC24A2,AKAP6,AKAP5,NOS1AP,DBI,GRIN3A,DMD,DRD1,EDNRA,CACNG7,CALCRL,CACNG3,CACNG2,PTK2B,FGF14,ATP2C1,SARAF,OGA,FYN,JPH4,INPP5K,GCK,GNAO1,GPM6A,MCHR1,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,IGF1,ITGAV,SLC35G1,MYO5A,NOS1,NPY,NPPA,OPRL1,P2RX7,PDE2A,PDE4B,PDE4D,PDPK1,NALCN,PKD1,PPP3CA,PRKCB,RYR1,RYR3,RASA3,SLC8A2,SLC8A1,SLC8A3,SLN,SNCA,TPCN2,TRPC1,TRPC3,TRPM2,BEST1,P2RY12,WNK3,JPH3" GO: Biological Process GO:1901379 regulation of potassium ion transmembrane transport 1.56E-04 1.00E+00 3.61E-03 3.53E-02 25 66 "ACTN2,DPP10,ANK2,ANK3,KCNAB2,ATP1B3,CACNA1D,AKAP7,AKAP6,NOS1AP,DNM2,DPP6,EDN3,FHL1,CAB39,KCNC1,KCNC2,KCNH2,KCNN2,NPPA,KCNIP3,KCNIP2,KCNIP1,KCNE5,KCNAB1" GO: Biological Process GO:0006873 cellular ion homeostasis 1.66E-04 1.00E+00 3.83E-03 3.74E-02 147 607 "ADCY5,ADCYAP1R1,SLC12A5,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,CLCN3,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,DBI,HEPH,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,PTK2B,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,KCNMA1,AQP11,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,RAB39A,SLC26A11,PTH1R,PTK2,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,TRPC1,TRPC3,TRPM2,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0098771 inorganic ion homeostasis 1.71E-04 1.00E+00 3.94E-03 3.85E-02 166 698 "ADCY5,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK1,ANK2,ANK3,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,CLCN3,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,SLC4A7,SLC4A8,CP,DBI,HEPH,FBXL5,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,EGFR,PTK2B,FECH,ATP13A4,TMEM175,NPTN,ATP6V1H,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNH2,KCNJ10,KCNK3,KCNMA1,SFXN5,AQP11,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,RAB39A,SLC26A11,CNNM2,PTH1R,PTK2,PYGM,RAP1GDS1,KCTD17,LRRK2,RYR1,RYR3,S100B,SCN7A,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC4A3,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,SPX,TRPC1,TRPC3,TRPM2,CA14,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC30A3,SLC30A4,TMEM178A,SLC17A7,TTC7A,SLC39A12,SLC4A10,JPH3" GO: Biological Process GO:0048864 stem cell development 1.76E-04 1.00E+00 4.05E-03 3.95E-02 56 192 "AXIN2,SEMA6A,SEMA7A,EPB41L5,SEMA4G,DACT3,ADAM15,NRP2,BMP7,LDLRAD4,NOG,ZEB2,EDN1,EDN3,EDNRA,EDNRB,HEYL,SEMA3D,ERBB4,OLFM1,MAD2L2,FOXF2,SEMA6C,SEMA4D,GBX2,GCNT2,LOXL3,HAS2,RBPJ,LIMS1,KITLG,PAX6,SEMA5B,MAPK3,RET,TMEM100,SOX8,SEMA6D,FUZ,SOX10,SOX11,PBLD,CLASP2,PHLDB1,SEMA4A,TCF7L2,CLASP1,DICER1,TGFBR3,HEY1,HEY2,WNT7A,CRB2,SEMA3B,RTN4,VANGL2" GO: Biological Process GO:0097091 synaptic vesicle clustering 1.81E-04 1.00E+00 4.14E-03 4.04E-02 7 9 "CDH2,NRXN1,MAGI2,PCDH17,NLGN3,SYNDIG1,NLGN1" GO: Biological Process GO:0060119 inner ear receptor cell development 1.81E-04 1.00E+00 4.14E-03 4.04E-02 21 52 "ATP2B2,WHRN,SLC4A7,USH1C,WDPCP,ADGRV1,SEC24B,FGFR1,GABRA5,GABRB3,CECR2,KIF3A,HES5,MYO7A,STRC,FAT4,DICER1,HEY1,PCDH15,VANGL2,IFT88" GO: Biological Process GO:0086001 cardiac muscle cell action potential 1.81E-04 1.00E+00 4.14E-03 4.04E-02 21 52 "ANK2,ANK3,ATP1A1,ATP1A2,ATP2A2,CACNA1G,CACNA1D,CACNA2D1,CACNB2,CAMK2D,NOS1AP,DMD,FGF12,KCND2,KCNH2,CTNNA3,SCN2B,SCN4B,SLC8A1,SCN3B,KCNE5" GO: Biological Process GO:0030517 negative regulation of axon extension 1.82E-04 1.00E+00 4.15E-03 4.05E-02 19 45 "SEMA6A,SEMA7A,SEMA4G,CDK5R1,SLIT2,AATK,SEMA3D,CDKL3,SEMA6C,SEMA4D,MT3,SEMA5B,SEMA6D,DRAXIN,SLIT1,SEMA4A,TNR,SEMA3B,RTN4" GO: Biological Process GO:0050954 sensory perception of mechanical stimulus 1.83E-04 1.00E+00 4.17E-03 4.08E-02 55 188 "ASIC2,AQP4,SPTBN4,ATP2B2,ALDH7A1,CACNA1D,ASIC3,CHRNB2,NIPBL,WHRN,COL11A2,CRYM,LRIG1,RIPOR2,GSDME,FAM107B,DNM1,USH1C,ADGRV1,EYA1,FGFR1,FYN,GABRA5,GABRB3,SRRM4,GRIN2D,GRM7,GRM8,HTR2A,IGF1,KCNA1,KCNMA1,KIT,MBP,MYO6,MYO7A,NDP,OTOGL,SERPINE2,TMIE,POU3F4,STRC,RAB3A,MYH14,RPL38,SCN8A,FBXO11,SLC1A3,SLC12A2,SOX2,TBL1X,TJP1,TUB,PCDH15,NAV2" GO: Biological Process GO:1900371 regulation of purine nucleotide biosynthetic process 1.84E-04 1.00E+00 4.17E-03 4.08E-02 46 150 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,APLP1,CALM1,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,CAP2,GABBR1,GALR1,PPARGC1A,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,HRH3,HPCA,P2RY13,NF1,NOS1,NUCB2,OPRL1,PALM,PDE2A,PTHLH,PID1,MRAP2,GPR161,VIPR2" GO: Biological Process GO:1900542 regulation of purine nucleotide metabolic process 1.86E-04 1.00E+00 4.21E-03 4.11E-02 64 227 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,OGT,APLP1,CALM1,CBS,CHGA,AKAP6,AKAP5,AKAP12,NCOR1,HDAC4,DRD1,DNM1L,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,RACK1,PRKAG2,CAP2,GABBR1,GALR1,GCK,PPARGC1A,RUNDC3A,GNAL,GNAS,GPD1,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,HRH3,HPCA,HTR2A,IGF1,P2RY13,NF1,NOS1,NUCB2,OPRL1,P2RX7,PALM,PDE2A,PDE4D,SLC25A23,PPARA,MAPK7,PTHLH,PID1,MRAP2,SNCA,GPR161,VIPR2" GO: Biological Process GO:0072511 divalent inorganic cation transport 1.87E-04 1.00E+00 4.22E-03 4.13E-02 115 458 "ASIC1,SLC25A25,ADCYAP1R1,ADORA2A,ADRB2,SLC24A4,AGT,PLA2G6,ANK2,CACHD1,CASK,ARRB2,ASPH,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,NIPA1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPN3,RGN,CACNA2D2,CBARP,CHRNA4,CHRNB2,SLC24A2,AKAP6,AKAP5,NOS1AP,DBI,GRIN3A,DMD,DRD1,EDNRA,CACNG7,CALCRL,CACNG3,CACNG2,PTK2B,FGF14,ATP2C1,SARAF,OGA,FYN,JPH4,INPP5K,GCK,GNAO1,GPM6A,MCHR1,GPER1,GRIN1,CACFD1,GRM7,IL1RAPL1,HTR2A,IGF1,ITGAV,SLC35G1,MT3,MYO5A,NOS1,NPY,NPPA,SLC11A2,OPRL1,P2RX7,PDE2A,PDE4B,PDE4D,PDPK1,NALCN,PIK3C2A,PKD1,PPP3CA,PRKCB,CNNM2,RYR1,RYR3,SLC30A10,RASA3,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SLN,SNCA,TPCN2,TF,TRPC1,TRPC3,TRPM2,BEST1,P2RY12,SLC30A3,SLC30A4,WNK3,SLC39A12,JPH3" GO: Biological Process GO:0009261 ribonucleotide catabolic process 1.92E-04 1.00E+00 4.30E-03 4.20E-02 16 35 "AMPD3,PDE8B,ENTPD4,GMPR2,RACK1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7,PRTFDC1" GO: Biological Process GO:0090218 positive regulation of lipid kinase activity 1.92E-04 1.00E+00 4.30E-03 4.20E-02 16 35 "CD81,CDC42,EEF1A2,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,KIT,PDGFRA,PTK2,AMBRA1,TEK,VAV2" GO: Biological Process GO:0071869 response to catecholamine 1.92E-04 1.00E+00 4.30E-03 4.20E-02 16 35 "ADCY6,APLP1,APP,AKAP6,DNM2,DRD1,PPARGC1A,GNAS,NOS1,PDE4B,PDE4D,GNG2,PENK,LRRK2,SIRT2,SNCA" GO: Biological Process GO:0043523 regulation of neuron apoptotic process 1.92E-04 1.00E+00 4.30E-03 4.20E-02 66 236 "ADORA2A,AGT,ASCL1,ATM,CDK5R1,NAE1,CACNA1A,AIFM1,CDC42,CRLF1,CNTFR,HDAC4,DLX1,OPTN,EN2,PTK2B,FGFR3,AGAP2,FOXO3,STAMBP,FYN,GABRA5,CHL1,GABRB3,PPARGC1A,TOX3,KDM2B,GRIK2,GRIK5,GRIN1,NR3C1,JAK2,KCNB1,KCNMA1,LIG4,MEF2C,NRBP2,MT3,NCF2,NF1,NTRK2,PAK3,PDPK1,RETREG1,PPP2R2B,VSTM2L,PRKCG,MAPK8,OXR1,FBXW7,KCNIP3,DRAXIN,ITSN1,AMBRA1,CPEB4,SNCB,SNCA,FAIM2,UNC5B,SRPK2,STXBP1,TRIM2,SIRT1,BHLHB9,XRCC4,MAP3K12" GO: Biological Process GO:0046879 hormone secretion 1.94E-04 1.00E+00 4.33E-03 4.23E-02 93 357 "ABAT,ADCY5,ADORA1,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,BTK,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,CRY2,RIMS2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,EPHA5,FGFR1,OGA,GABBR1,ILDR2,GALR1,CPLX1,GCK,GDF9,GLUL,GNAS,GPER1,PCLO,RAPGEF4,HMGCR,HTR2A,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYO5A,MYT1,NELL2,NEUROD1,NNAT,NOS1,NUCB2,P2RY1,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,PTPRN,PTPRN2,RFX3,SMPD3,SCG5,SYBU,SNAP25,SOX11,STX1A,ABCC8,TAC1,TACR1,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:0032386 regulation of intracellular transport 1.94E-04 1.00E+00 4.33E-03 4.23E-02 160 671 "ACTN2,ADCYAP1R1,AXIN2,ADORA3,C1QTNF3,OGT,ANK2,ANK3,CNIH2,RGS20,ASPH,DACT3,DYNLL1,ATP1A2,ATP2A2,BARD1,BID,BMP7,CDK5R1,SYNJ1,MTMR2,RAB29,CALM1,HAP1,CAMK2D,CAPN3,BRSK2,CDC42,CHRM1,AKAP6,CABP1,AKAP5,BAG4,RIMS4,RIMS2,TCAF1,RIMS3,DBI,DBN1,B3GAT3,G3BP2,DMD,DNM1,DRD1,FIS1,EDNRA,SH3GLB1,EGFR,TENM1,DMTN,ERBB2,ERBB4,APC2,DNAJC27,TLR7,REEP2,PTK2B,RACK1,SEC24B,FER,FGF14,FGR,ZBED3,PRELID3A,OGA,JPH4,INPP5K,OS9,GPR26,GPER1,GRIK5,KIF3A,PTPN5,BVES,HNMT,HPCA,HSPA1L,HSP90AA1,MYLK2,IGF1,JAK2,KCNB1,KCNN3,IPO5,MAPT,LYPLAL1,MDFI,MXI1,MYBPC1,MYO5A,NEFH,NF1,NODAL,NOS1,NUCB1,OGG1,P2RX7,PDE2A,PDE4D,PDPK1,ZDHHC8,PIK3R1,PKD1,MED1,PPM1B,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PKIA,MAPK3,MAPK7,MAPK8,BCAS3,RAB3A,SH3TC2,RDX,FBXW7,LRRK2,STX1B,SCP2,ELMOD1,NLGN1,ABLIM3,SLC8A1,RAB3GAP1,NAPB,RIMS1,SNCA,PBLD,STX1A,KANK1,SULF2,STXBP1,MLC1,SYN1,MTCL1,WWC1,FBXW11,TCF7L2,TEK,ATP13A2,SIRT1,THRA,TLR4,TP53BP2,TRPC1,TRPC3,WIPF1,XPO1,ZIC1,NDRG4,REEP1,MFF,HPS4,C12orf4,GOPC,NLRP3,AAAS,JPH3" GO: Biological Process GO:0006937 regulation of muscle contraction 1.98E-04 1.00E+00 4.39E-03 4.29E-02 49 163 "ABAT,ADORA1,ADRA1D,ADRA1B,ADRB2,ANK2,ASPH,ATP1A1,ATP1A2,ATP2A2,CALM1,CAMK2D,CHGA,CHRM1,AKAP6,NOS1AP,DOCK4,HDAC4,DAPK3,DBN1,DMD,DMPK,EDN1,CALCRL,MRVI1,FLT1,GPER1,GUCY1A1,HSP90AA1,MYLK2,KCNA1,KCNMA1,CTNNA3,MYH7,MYL3,NOS1,NPPA,OXTR,PDE4B,PDE4D,FXYD1,PTAFR,RYR1,SLC8A1,SLC8A3,SSTR2,TACR1,TNNT1,TPM1" GO: Biological Process GO:0090257 regulation of muscle system process 2.05E-04 1.00E+00 4.55E-03 4.45E-02 62 219 "ABAT,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,ANK2,PI16,ASPH,ATP1A1,ATP1A2,ATP2A2,CALM1,CAMK2B,CAMK2D,CAMK2G,CHGA,CHRM1,AKAP6,NOS1AP,DOCK4,HDAC4,DAPK3,DBN1,DMD,DMPK,EDN1,CALCRL,MRVI1,FLT1,OGA,MSTN,PPARGC1A,GPER1,NR3C1,GUCY1A1,HSP90AA1,MYLK2,IGF1,IL6ST,KCNA1,KCNMA1,CTNNA3,MYH7,MYL3,NOS1,NPPA,OXTR,PDE4B,PDE4D,FXYD1,PPP3CA,PTAFR,RYR1,SLC8A1,SLC8A3,SLN,SSTR2,TACR1,TNNT1,TPM1,TRPC3" GO: Biological Process GO:1903725 regulation of phospholipid metabolic process 2.06E-04 1.00E+00 4.55E-03 4.45E-02 25 67 "ADGRF5,APOC1,APOC2,CCKBR,SCARB1,CD81,CDC42,RUBCN,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,HTR2A,KIT,PC,PDGFRA,PIK3R1,PTK2,AMBRA1,TEK,PIK3R5,VAV2" GO: Biological Process GO:1902667 regulation of axon guidance 2.13E-04 1.00E+00 4.71E-03 4.60E-02 18 42 "SEMA6A,SEMA7A,SEMA4G,SLIT2,PLXNA4,DSCAM,SEMA3D,PLXNC1,SEMA6C,SEMA4D,TBR1,SEMA5B,PTPRO,FEZF2,SEMA6D,SLIT1,SEMA4A,SEMA3B" GO: Biological Process GO:0007616 long-term memory 2.15E-04 1.00E+00 4.74E-03 4.63E-02 15 32 "ADCY8,CALB1,SHANK1,GRIA1,GRIN1,NTRK2,PRKCZ,RELN,RASGRF1,SGK1,CPEB3,SNAP25,TAC1,TACR1,SLC17A7" GO: Biological Process GO:0051931 regulation of sensory perception 2.16E-04 1.00E+00 4.74E-03 4.63E-02 20 49 "ADORA1,ADRB2,CCK,CCKBR,EDN1,EDNRB,FCGR3A,FGFR1,GRIN2D,GRM1,GRM3,KCNJ10,NCAM1,NOS1,OPRL1,PTAFR,TMEM100,SPX,TLR4,RTN4" GO: Biological Process GO:0051930 regulation of sensory perception of pain 2.16E-04 1.00E+00 4.74E-03 4.63E-02 20 49 "ADORA1,ADRB2,CCK,CCKBR,EDN1,EDNRB,FCGR3A,FGFR1,GRIN2D,GRM1,GRM3,KCNJ10,NCAM1,NOS1,OPRL1,PTAFR,TMEM100,SPX,TLR4,RTN4" GO: Biological Process GO:0030808 regulation of nucleotide biosynthetic process 2.18E-04 1.00E+00 4.77E-03 4.66E-02 46 151 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,APLP1,CALM1,AKAP6,AKAP5,AKAP12,DRD1,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,CAP2,GABBR1,GALR1,PPARGC1A,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,HRH3,HPCA,P2RY13,NF1,NOS1,NUCB2,OPRL1,PALM,PDE2A,PTHLH,PID1,MRAP2,GPR161,VIPR2" GO: Biological Process GO:1901660 calcium ion export 2.30E-04 1.00E+00 5.03E-03 4.91E-02 6 7 "ATP2B1,ATP2B2,SLC35G1,SLC8A2,SLC8A1,SLC8A3" GO: Biological Process GO:1901699 cellular response to nitrogen compound 2.32E-04 1.00E+00 5.07E-03 4.95E-02 144 597 "ACTN2,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,AGT,OSBPL8,OGT,APLP1,GPAM,APP,ATP6V1G2,ATP6V0A1,HCN2,BLM,CDK5R1,CAMK2A,AIFM1,NEURL1,ARHGEF2,CHRM1,CHRM4,SLIT2,AKAP7,AKAP6,AKAP5,CPS1,CRHBP,NCOR1,NCOR2,APPL1,HDAC9,DNM2,CPEB2,DRD1,EDN1,EGFR,DMTN,RRAGB,FER,BAIAP2,FOLR2,SORBS1,ATP6V1H,FYN,GAB1,GABRA1,GABRB1,GABRB3,GABRG2,AHCYL1,INPP5K,GCK,MSTN,SESN1,GHR,PPARGC1A,GNAS,GNG3,GNG4,GPD1,GPER1,GRB10,RAPGEF1,GUCY1B1,HRH3,HNRNPK,IGF1,IGFBP1,JAK2,KCNC2,KCNJ11,KCNQ3,IPO5,SMAD1,MEF2C,SESN3,MT3,MTR,MYO5A,VWA2,NOS1,HCN1,NTRK2,NUCB2,P2RX7,TREM2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDGFRA,PDPK1,GPR173,GNG2,PENK,SSH1,PIK3C2A,PIK3R1,PRKACB,PRKAR1B,PRKCB,PRKCZ,MAPK3,MAPK8,PTAFR,PTK2,PTPRE,CASTOR1,PID1,RGS10,RNASEL,RPE65,LRRK2,RXRA,RYR1,RYR3,SGK1,CPEB3,SLC8A1,SLC8A3,SIRT2,CPEB4,SNCA,MBD5,LMBRD1,WDTC1,SSTR1,SSTR2,KANK1,PLCB1,ZEB1,DICER1,SIRT1,ZNF106,METTL3,STXBP4,TSC1,TSC2,VLDLR,P2RY12,ATP6V0E2" GO: Biological Process GO:0035640 exploration behavior 2.37E-04 1.00E+00 5.14E-03 5.02E-02 14 29 "ABAT,CHRNA4,DLG4,CHL1,GAD1,PTPN5,LRRTM1,LSAMP,PENK,LRRK2,SHANK2,TNR,SLC4A10,JPH3" GO: Biological Process GO:0043954 cellular component maintenance 2.37E-04 1.00E+00 5.14E-03 5.02E-02 14 29 "SHROOM2,ADGRB3,MTMR2,PICK1,WHRN,CSF1R,MYADM,PARD6A,C1QL1,ITPKA,KIFC3,AFDN,RAB3A,ZMYND8" GO: Biological Process GO:0030072 peptide hormone secretion 2.37E-04 1.00E+00 5.14E-03 5.02E-02 76 282 "ABAT,ADCY5,PLA2G6,LTBP4,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,RIMS2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,EPHA5,OGA,GABBR1,ILDR2,CPLX1,GCK,GLUL,GNAS,GPER1,PCLO,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYO5A,MYT1,NEUROD1,NNAT,NOS1,NUCB2,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,PTPRN,PTPRN2,RFX3,SMPD3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:2000179 positive regulation of neural precursor cell proliferation 2.48E-04 1.00E+00 5.34E-03 5.22E-02 21 53 "DISP3,ASCL1,NOG,GPR37L1,ADGRG1,CX3CR1,DCT,CDON,FOXG1,DISC1,GLI2,IGF1,INSM1,PAX6,PROX1,SMARCD3,SOX2,SOX10,TF,NR2E1,FZD3" GO: Biological Process GO:0050433 regulation of catecholamine secretion 2.48E-04 1.00E+00 5.34E-03 5.22E-02 21 53 "ABAT,ADORA2A,AGT,CHGA,CHRNA4,CHRNB2,CNR1,GABBR1,GCK,HRH3,HTR2A,KCNA2,KCNB1,OXTR,P2RY1,PLCD1,PRKCB,SNCA,STX1A,P2RY12,RTN4" GO: Biological Process GO:0051955 regulation of amino acid transport 2.48E-04 1.00E+00 5.34E-03 5.22E-02 17 39 "ABAT,ADORA1,ADORA2A,AGT,ATP1A2,CCK,DPYSL2,GABBR1,GRIK1,NR3C1,GRM7,HRH3,P2RX7,SLC6A1,RAB3GAP1,SNCA,TRH" GO: Biological Process GO:0021533 cell differentiation in hindbrain 2.54E-04 1.00E+00 5.45E-03 5.32E-02 13 26 "ATP2B2,CACNA1A,CBLN1,NOG,NRXN1,CEND1,KNDC1,NFIX,PROX1,ATXN2,FAIM2,AGTPBP1,WNT7A" GO: Biological Process GO:0021952 central nervous system projection neuron axonogenesis 2.54E-04 1.00E+00 5.45E-03 5.32E-02 13 26 "SPTBN4,DCLK1,CHRNB2,SLIT2,PLXNA4,DCC,ZEB2,EPHB1,GLI2,MYCBP2,SZT2,NR2E1,PRDM8" GO: Biological Process GO:1903727 positive regulation of phospholipid metabolic process 2.57E-04 1.00E+00 5.49E-03 5.36E-02 19 46 "ADGRF5,APOC2,CD81,CDC42,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,HTR2A,KIT,PC,PDGFRA,PTK2,AMBRA1,TEK,VAV2" GO: Biological Process GO:0032288 myelin assembly 2.62E-04 1.00E+00 5.58E-03 5.45E-02 11 20 "ANK2,CNTNAP1,PRX,MTMR2,TENM4,ERCC2,PMP22,NFASC,EPB41L3,DICER1,UGT8" GO: Biological Process GO:0006875 cellular metal ion homeostasis 2.62E-04 1.00E+00 5.58E-03 5.45E-02 127 518 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK2,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,CP,DBI,HEPH,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,PTK2B,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,KCNMA1,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,TRPC1,TRPC3,TRPM2,SGK3,SLC30A3,SLC30A4,TMEM178A,TTC7A,SLC39A12,JPH3" GO: Biological Process GO:0009214 cyclic nucleotide catabolic process 2.64E-04 1.00E+00 5.61E-03 5.48E-02 12 23 "PDE8B,RACK1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7" GO: Biological Process GO:1900543 negative regulation of purine nucleotide metabolic process 2.69E-04 1.00E+00 5.69E-03 5.56E-02 25 68 "APLP1,AKAP6,AKAP5,HDAC4,EDN1,EDNRA,EDNRB,GABBR1,GALR1,PPARGC1A,GRM2,GRM3,GRM7,GRM8,HRH3,HPCA,P2RY13,NUCB2,OPRL1,PALM,PDE2A,PPARA,MAPK7,PID1,SNCA" GO: Biological Process GO:0021779 oligodendrocyte cell fate commitment 2.72E-04 1.00E+00 5.69E-03 5.56E-02 5 5 "ASCL1,OLIG2,NKX2-2,PAX6,SOX6" GO: Biological Process GO:1900454 positive regulation of long-term synaptic depression 2.72E-04 1.00E+00 5.69E-03 5.56E-02 5 5 "STAU2,KCNB1,MAPT,PPP1R9A,IQSEC2" GO: Biological Process GO:0016199 axon midline choice point recognition 2.72E-04 1.00E+00 5.69E-03 5.56E-02 5 5 "APP,FOXG1,ROBO1,ROBO2,ROBO3" GO: Biological Process GO:0021778 oligodendrocyte cell fate specification 2.72E-04 1.00E+00 5.69E-03 5.56E-02 5 5 "ASCL1,OLIG2,NKX2-2,PAX6,SOX6" GO: Biological Process GO:0021780 glial cell fate specification 2.72E-04 1.00E+00 5.69E-03 5.56E-02 5 5 "ASCL1,OLIG2,NKX2-2,PAX6,SOX6" GO: Biological Process GO:0050432 catecholamine secretion 2.78E-04 1.00E+00 5.81E-03 5.68E-02 22 57 "ABAT,ADORA2A,AGT,CADPS,CHGA,CHRNA4,CHRNB2,CNR1,GABBR1,GCK,HRH3,HTR2A,KCNA2,KCNB1,OXTR,P2RY1,PLCD1,PRKCB,SNCA,STX1A,P2RY12,RTN4" GO: Biological Process GO:0045055 regulated exocytosis 2.81E-04 1.00E+00 5.86E-03 5.73E-02 83 315 "SERPINA3,ABR,ACTN1,ACTN2,ADORA3,SYT13,DOC2A,APP,CADPS,ATP2A2,SYNJ1,BTK,CACNA1I,CACNA1G,CDK5R2,CACNA1A,CALM1,SYT6,CBARP,CHGA,CLU,RAB26,CRHBP,RIMS4,RIMS2,SNPH,RIMS3,BLOC1S6,SYT15,RASGRP1,DMTN,STX2,F5,F8,PRAM1,FER,FGR,SYT3,BRPF3,SYT17,CPLX2,CPLX1,PCLO,RAPGEF4,GRIK5,IGF1,SCIN,C2CD4C,KCNB1,KIT,LAMP2,SYTL4,SYT9,SCAMP5,SCG3,P2RX7,PDPK1,PIK3CD,PPP3CB,SYTL2,PTAFR,RAB3A,LRRK2,STX1B,NLGN1,RPH3A,RAB3GAP1,NAPB,RIMS1,SNAP25,STX1A,STXBP1,SYT11,PLCB1,SYN1,SYT1,SYT4,SYT5,TF,LEFTY2,LAT2,TRIM9,C12orf4" GO: Biological Process GO:0006941 striated muscle contraction 2.82E-04 1.00E+00 5.88E-03 5.74E-02 48 161 "ADORA1,ADRA1B,ADRB2,ANK2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP2A2,CACNA2D1,CACNB2,CALM1,CAMK2D,CHGA,AKAP6,NOS1AP,HDAC4,DMD,DMPK,DTNA,RCSD1,FGF12,GAA,ATP8A2,HSP90AA1,MYLK2,KCNH2,CTNNA3,MYH3,MYH6,MYH7,MYL3,NOS1,NPPA,PDE4B,PDE4D,PGAM2,FXYD1,MYH14,RYR3,SCN2B,SCN4B,SLC8A1,SLC8A3,SCN3B,TNNT1,TPM1,KCNE5" GO: Biological Process GO:0042325 regulation of phosphorylation 2.86E-04 1.00E+00 5.95E-03 5.81E-02 329 1510 "NDRG2,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,APC,ALS2,LRRC4C,APP,CDK10,MADD,SPTBN4,ZFYVE28,ARRB1,ARRB2,CAPRIN2,DYNLL1,ATM,EIF4G3,RIPK1,BARD1,BLM,KSR1,BMP7,CDK5R1,C5,CDK5R2,LDLRAD4,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CBS,CCK,LDB2,CCKBR,CCNH,CCNT1,RGN,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,NOG,CRLF1,GPR37L1,SOCS6,TAOK2,SLIT2,CLU,FBXO7,MAP4K4,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,NCOR1,CLIP3,CSF1,CSF1R,SOCS5,CTNND1,RUBCN,MYADM,HDAC4,RASSF2,DCC,ZEB2,PARD6A,DMD,CDON,DRD1,ABI1,DSCAM,DUSP9,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,HIPK3,RASGRP1,SH3GLB1,CELSR3,EGFR,SORBS3,TENM1,TNK2,DMTN,EPHB1,ERBB2,ERBB4,DNAJC27,TLR7,PTK2B,TAOK3,RACK1,FKTN,STRADA,PRMT5,PPP1R1B,FECH,FER,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,AGAP2,RGPD5,FOXM1,SEMA4D,FLT1,ZBED3,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,ZMYND11,ZNF274,INPP5K,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,COPS8,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,C1QL4,GRIK2,GRM1,GRM5,PTPN5,MAP4K5,IRAK3,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HTR2A,MYLK2,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,INSM1,LRRTM3,LRRTM1,ITGAV,ITPKB,JAK2,KIT,LRRC4B,CAMK2N2,FGFBP3,PIK3AP1,MDFI,KITLG,MID1,DBNL,MT3,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PAX6,PDE4D,PDGFRA,ENPP2,PDPK1,PFKFB2,DUSP26,PIK3R1,PKD1,PLCL1,SLC25A23,PPARA,PPP1R1A,LRRN3,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCZ,MAPK3,MAPK7,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTK2,PTPRZ1,PPP2R3C,PID1,RAD17,DUSP15,RET,RGS3,RGS4,KIRREL1,FBXW7,PRR5L,LRRK2,ATXN1,ATXN7,LRRTM4,FNIP1,TNFRSF19,ITSN1,PPP1R9A,PPM1E,MAGI3,AMBRA1,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,MAPKBP1,SNCA,LMBRD1,SOX2,TNIK,DBNDD2,TSPYL2,LMO3,TAB2,PBLD,STOX1,SAMSN1,LRRC4,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,NSD1,TEK,TF,DICER1,SIRT1,LEFTY2,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PARD3,PIK3R5,IL34,NTSR2,TSC1,TSC2,UBC,UCHL1,FLRT2,FLRT1,VAV2,MICAL1,VLDLR,WNT7A,RICTOR,NDRG4,WNK1,PMEPA1,MAP3K12,LRP8,RGMA,WNK3,WNK2,NELFE,VANGL2,SOCS4" GO: Biological Process GO:0021696 cerebellar cortex morphogenesis 2.87E-04 1.00E+00 5.95E-03 5.81E-02 16 36 "ATP2B2,CACNA1A,CBLN1,NRXN1,WHRN,CEND1,GLI2,KNDC1,NFIX,SERPINE2,PROX1,RFX4,ATXN2,FAIM2,AGTPBP1,WNT7A" GO: Biological Process GO:0050877 nervous system process 2.92E-04 1.00E+00 6.04E-03 5.90E-02 308 1405 "ABR,ASIC2,ASIC1,ADCY5,ADCY8,SLC12A5,FZD9,ADORA1,ADORA2A,PTCHD1,ADRA1D,ADRA1B,ADRB2,NLGN4X,SLC24A4,AGT,PLA2G6,AMPH,ANK3,CNTNAP1,APBB1,KCNAB2,APP,AQP4,PRX,SPTBN4,ARRB2,PDE8B,ATP1A2,ATP1A3,ATP2B2,ALDH7A1,AZGP1,ADGRB3,BBS2,BCHE,RGS9,SYNJ1,MTMR2,CACNA1I,MYRF,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB2,CACNB4,CALB1,KALRN,NGB,CAMK2B,CCK,CCKBR,DGKI,NOG,ASIC3,CHM,CHRM1,CHRNA4,CHRNB2,NRXN3,NRXN1,NRXN2,SLC24A2,TPP1,VAX2,NIPBL,CNGA3,CNR1,WHRN,COL11A2,SLC4A7,IGDCC3,ZNF385A,PNKD,CRHBP,CRYBB1,CRYM,TENM4,LRIG1,CNTNAP2,CTNND2,CX3CR1,RIPOR2,DBI,DBN1,GSDME,FAM107B,DLG2,DLG4,GRIN3A,DNM1,SHANK1,DPP6,DRD1,RCAN1,USH1C,EDN1,EDNRA,EDNRB,CACNG7,EGFR,ABI2,ELAVL4,RCAN2,EPHB1,KCNMB2,ADGRV1,EYA1,REEP2,FABP7,CACNG3,CACNG2,EFEMP1,ATP8A1,FCGR3A,PPP1R1B,FGF12,FGF13,FGF14,FGFR1,AFF2,NPTN,TBR1,FYN,GAA,GABRA5,CHL1,GABRB3,JPH4,NKX6-2,ATP8A2,SRRM4,WASF3,C1QL1,GLRB,GLS,KCNMB4,GNAL,GNAS,GPER1,RAPGEF4,GRIA1,GRIK2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM3,GRM5,GRM7,GRM8,HRH3,HMGCR,HTR2A,IGF1,KCNA1,KCNA2,KCND2,KCNH1,KCNJ10,KCNJ11,KCNK2,KCNMA1,KCNQ2,KIFC3,KIT,FGFBP3,MAG,GPR155,MBP,SHC3,MEF2C,MEIS2,MYO5A,MYO6,MYO7A,MYO9A,NCAM1,NDP,NEUROD2,NF1,OTOGL,NOS1,NPTX2,SLC11A2,NRCAM,NRGN,NTRK2,GPR88,OPA1,OPRL1,OXTR,P2RX7,P2RY1,KCNK10,PAX6,PDE1C,PDE4A,PDE1B,PDYN,PENK,TMOD2,NLGN3,SERPINE2,SEMA5B,TMIE,RETREG1,PLCB2,JAKMIP1,POU3F4,DRAM2,PPP3CB,PRKAR1B,PRKCG,PRKCZ,MAPK3,RELN,PTAFR,PTN,PTPRZ1,PEX5,STRC,RAB3A,RASGRF1,PRRT2,RGR,RLBP1,MYH14,ROM1,RORB,RPE65,TMEM100,RPL38,RPS6KA2,KCNIP3,S100B,ATXN1,ATXN2,ATXN7,SCN2A,SCN3A,SCN7A,SCN8A,SCNN1D,PRCD,NLGN4Y,SGK1,CPEB3,FBXO11,NLGN1,SLC1A3,SLC6A1,SLC8A2,SLC8A3,SHANK2,SLC12A2,RTP5,SORCS3,RIMS1,SNAP25,ANKFN1,SCN3B,SOX2,SPATA7,NPAS3,SPART,NFASC,PLCB1,ARC,TAC1,TACR1,DDHD2,CAMTA1,CNTN2,AGTPBP1,TBL1X,CUX2,CRTC1,TF,DICER1,SPX,THRA,TJP1,BHLHB9,TLR4,NR2E1,CSMD1,PARD3,TNR,RBFOX2,NTSR2,TUB,UCHL1,VLDLR,BEST1,ZIC2,NDRG4,PCDH15,NAV2,SLC17A7,KCNAB1,EPM2A,RTN4,PAK5,AAAS,NETO1,JPH3" GO: Biological Process GO:0043279 response to alkaloid 2.93E-04 1.00E+00 6.05E-03 5.91E-02 47 157 "ABAT,ADORA2A,ADRA1B,ATP1A2,BCHE,BLM,KALRN,CHRNA4,CHRNB2,CNR1,CRHBP,LYPD1,DLG4,DNM2,DPYSL2,DRD1,EDN1,EDNRA,PTK2B,GABBR1,PPARGC1A,GNAL,GNAO1,GRIN1,HNMT,HTR2A,IGF1,KCNJ11,KCNK1,MBD1,NCAM1,NEFH,NOS1,OXTR,PENK,PPARA,PPP5C,PRKCG,RYR1,RYR3,SLC6A1,SLC8A1,SNCA,TAC1,TACR1,ADGRL3,TIAM1" GO: Biological Process GO:0048675 axon extension 2.97E-04 1.00E+00 6.12E-03 5.97E-02 41 132 "SEMA6A,ALCAM,SEMA7A,SHTN1,SEMA4G,NRP2,CDK5R1,DCLK1,SLIT2,LHX2,AATK,PLXNA4,DBN1,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,SEMA6C,SEMA4D,DISC1,L1CAM,MAPT,MT3,NRCAM,NTRK3,NLGN3,SEMA5B,PLXNB1,PPP3CB,SEMA6D,DRAXIN,SLIT1,CLASP2,SEMA4A,TNR,SEMA3B,RTN4" GO: Biological Process GO:0097581 lamellipodium organization 2.98E-04 1.00E+00 6.12E-03 5.97E-02 27 76 "ARHGEF7,WASF1,SLIT2,ARHGEF6,SH2B1,ARHGEF4,HDAC4,DNM2,ABI1,PLEKHO1,DMTN,MTSS1L,FER,NCKAP1,WASF3,HSP90AA1,KIT,ENPP2,SSH1,PLXNB3,PTPRO,ABLIM3,CCDC88A,KANK1,FGD4,VAV2,SPATA13" GO: Biological Process GO:0046883 regulation of hormone secretion 2.99E-04 1.00E+00 6.12E-03 5.97E-02 80 302 "ABAT,ADCY5,ADORA1,AGT,PLA2G6,C1QTNF1,C1QTNF3,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,CRY2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,EPHA5,FGFR1,OGA,GABBR1,GALR1,GCK,GDF9,GLUL,GNAS,GPER1,RAPGEF4,HMGCR,HTR2A,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYT1,NELL2,NEUROD1,NNAT,NOS1,NUCB2,P2RY1,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,RFX3,SCG5,SYBU,SNAP25,SOX11,STX1A,ABCC8,TAC1,TACR1,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VSNL1" GO: Biological Process GO:0006140 regulation of nucleotide metabolic process 2.99E-04 1.00E+00 6.12E-03 5.97E-02 65 235 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,OGT,APLP1,CALM1,CBS,CHGA,AKAP6,AKAP5,AKAP12,NCOR1,HDAC4,DRD1,DNM1L,EDN1,EDNRA,EDNRB,CALCRL,PTK2B,RACK1,PRKAG2,CAP2,GABBR1,GALR1,GCK,PPARGC1A,RUNDC3A,GNAL,GNAS,GPD1,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,HRH3,HPCA,HTR2A,IGF1,P2RY13,NF1,NOS1,NUCB2,OPRL1,P2RX7,PALM,PDE2A,PDE4D,PGAM2,SLC25A23,PPARA,MAPK7,PTHLH,PID1,MRAP2,SNCA,GPR161,VIPR2" GO: Biological Process GO:0042327 positive regulation of phosphorylation 3.00E-04 1.00E+00 6.12E-03 5.97E-02 227 1003 "ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,ALS2,CDK10,MADD,ARRB1,ARRB2,CAPRIN2,ATM,EIF4G3,RIPK1,KSR1,BMP7,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CCK,CCNH,CCNT1,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,CRLF1,GPR37L1,TAOK2,CLU,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,CLIP3,CSF1,CSF1R,CTNND1,RASSF2,DCC,ZEB2,CDON,ABI1,DSCAM,DUSP9,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,RASGRP1,SH3GLB1,EGFR,SORBS3,TENM1,TNK2,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,AGAP2,SEMA4D,FLT1,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,GCK,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,MALT1,COPS8,GNAS,GNG3,PSRC1,GPD1,GPER1,GPR37,GRB10,RAPGEF1,GRM1,GRM5,PTPN5,MAP4K5,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HTR2A,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,ITGAV,JAK2,KIT,FGFBP3,MDFI,KITLG,MID1,DBNL,MT3,NELL1,NODAL,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PDGFRA,ENPP2,PDPK1,PFKFB2,PIK3R1,PKD1,LRRN3,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTK2,PTPRZ1,PPP2R3C,DUSP15,RET,FBXW7,PRR5L,LRRK2,FNIP1,TNFRSF19,ITSN1,PPP1R9A,MAGI3,AMBRA1,ANKRD6,CCDC88A,SLC11A1,MAPKBP1,SNCA,SOX2,TNIK,TAB2,STOX1,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,TEK,TF,SIRT1,LEFTY2,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PIK3R5,IL34,NTSR2,UBC,VAV2,VLDLR,WNT7A,RICTOR,NDRG4,MAP3K12,LRP8,RGMA,WNK3,NELFE,VANGL2" GO: Biological Process GO:0048762 mesenchymal cell differentiation 3.00E-04 1.00E+00 6.12E-03 5.97E-02 57 200 "AXIN2,SEMA6A,SEMA7A,EPB41L5,SEMA4G,DACT3,ADAM15,NRP2,BMP7,LDLRAD4,NOG,ZEB2,EDN1,EDN3,EDNRA,EDNRB,HEYL,SEMA3D,ERBB4,OLFM1,FGFR1,MAD2L2,FOXF2,SEMA6C,SEMA4D,GBX2,GCNT2,LOXL3,HAS2,RBPJ,LIMS1,MEF2C,KITLG,PAX6,SEMA5B,MAPK3,RET,TMEM100,SOX8,SEMA6D,FUZ,SOX10,SOX11,PBLD,CLASP2,PHLDB1,SEMA4A,TCF7L2,CLASP1,DICER1,TGFBR3,HEY1,HEY2,CRB2,SEMA3B,RTN4,VANGL2" GO: Biological Process GO:0002065 columnar/cuboidal epithelial cell differentiation 3.03E-04 1.00E+00 6.17E-03 6.03E-02 46 153 "ARNTL,ASCL1,ATP2B2,CDH2,SLC4A7,CLOCK,ZEB2,BLOC1S6,USH1C,WDPCP,EDN3,EDNRB,SIDT2,SEC24B,FGFR1,RBPJ,HES5,INSM1,KCNMA1,KIT,MEF2C,KITLG,MITF,AFDN,MYCN,MYO5A,MYO6,MYO7A,NEUROD1,NKX2-2,NODAL,PAX6,PDPK1,PROX1,STRC,TMEM231,RFX3,RXRA,SOX10,SOX11,DICER1,HEY1,HEY2,ADAMTS9,HPS4,PCDH15" GO: Biological Process GO:0001662 behavioral fear response 3.04E-04 1.00E+00 6.18E-03 6.03E-02 18 43 "ALS2,PDE8B,CACNA1E,KALRN,CCK,BRINP1,DBI,LYPD1,DRD1,EIF4G1,GABRA5,GRIK2,GRM7,MEF2C,NEUROD2,PENK,ANKFN1,NR2E1" GO: Biological Process GO:0007405 neuroblast proliferation 3.05E-04 1.00E+00 6.18E-03 6.03E-02 23 61 "FZD9,ASCL1,NUMB,NUMBL,CX3CR1,DCT,EML1,FGF13,FGFR1,FOXG1,DISC1,DOCK7,KCNA1,NF1,PAX6,LRRK2,SMARCD3,SOX2,SOX5,SOX10,ACSL6,HHIP,FZD3" GO: Biological Process GO:0030073 insulin secretion 3.16E-04 1.00E+00 6.38E-03 6.23E-02 64 231 "ABAT,ADCY5,PLA2G6,ARNTL,ARRB1,PDE8B,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,RIMS2,C2CD2L,SIDT2,EPHA5,OGA,ILDR2,CPLX1,GCK,GLUL,GNAS,GPER1,PCLO,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYO5A,MYT1,NEUROD1,NNAT,NOS1,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,PTPRN,PTPRN2,RFX3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:0021683 cerebellar granular layer morphogenesis 3.18E-04 1.00E+00 6.40E-03 6.25E-02 8 12 "ATP2B2,CBLN1,NRXN1,KNDC1,NFIX,SERPINE2,PROX1,WNT7A" GO: Biological Process GO:0014820 tonic smooth muscle contraction 3.18E-04 1.00E+00 6.40E-03 6.25E-02 8 12 "AGT,BBS2,CACNA1G,EDN1,EDN3,EDNRA,HTR2A,SMPD3" GO: Biological Process GO:0031279 regulation of cyclase activity 3.24E-04 1.00E+00 6.50E-03 6.35E-02 30 88 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,CALM1,AKAP5,DRD1,EDNRA,EDNRB,CAP2,GABBR1,GALR1,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,HRH3,HPCA,P2RY13,NF1,NOS1,PALM,MAPK3,MAPK8,VIPR2" GO: Biological Process GO:0015844 monoamine transport 3.24E-04 1.00E+00 6.50E-03 6.35E-02 30 88 "ABAT,ADORA2A,AGT,CADPS,CHGA,CHRNA4,CHRNB2,CNR1,PICK1,SLC29A4,DRD1,GABBR1,GCK,GPM6B,HRH3,HTR2A,KCNA2,KCNB1,NAT8L,MAOB,NOS1,OXTR,P2RY1,PLCD1,PRKCB,SMPD3,SNCA,STX1A,P2RY12,RTN4" GO: Biological Process GO:0016050 vesicle organization 3.31E-04 1.00E+00 6.62E-03 6.46E-02 91 353 "SNX30,AP1B1,SNX32,TBC1D14,SRPX,SYT13,DOC2A,CNIH2,ALS2,SHROOM2,CADPS,STX16,AP1M1,RAB29,SYT6,EVI5L,CLCN3,TBPL1,ZNF385A,SEC24C,CALY,USP6NL,SNPH,ZFYVE16,TBC1D5,ZEB2,CNIH3,BLOC1S6,SNAP91,SGSM2,RABGAP1L,SEC16A,DLG4,TRAPPC9,PDCD6IP,SYT15,STX2,F5,F8,TBC1D16,ATP8A1,SEC24B,VTI1B,ANKFY1,SYT3,TMEM175,NSG2,NSG1,SYT17,ATP8A2,GRIA1,GRIK5,ZDHHC15,AGFG1,C2CD4C,SYTL4,SYT9,BLOC1S2,MYO7A,TBC1D25,P2RX7,SERPINE2,PIK3C2A,SNX10,RAB39A,SYTL2,PTPRN,RAB3A,RFX2,SGSM1,STX1B,MYO18A,SEC31A,RPH3A,SNAP25,KIF13A,FCHO1,STX1A,STXBP1,SYT11,VAMP1,SYP,SYT1,ANKRD28,SYT4,SYT5,GORASP1,TBC1D15,TRIM9,EVI5,SLC17A7" GO: Biological Process GO:0030516 regulation of axon extension 3.31E-04 1.00E+00 6.62E-03 6.46E-02 34 104 "SEMA6A,SEMA7A,SHTN1,SEMA4G,CDK5R1,SLIT2,AATK,PLXNA4,DBN1,DNM2,DPYSL2,DSCAM,SEMA3D,PLXNC1,EIF4G2,CDKL3,OLFM1,SEMA6C,SEMA4D,DISC1,L1CAM,MAPT,MT3,NRCAM,NTRK3,SEMA5B,SEMA6D,DRAXIN,SLIT1,CLASP2,SEMA4A,TNR,SEMA3B,RTN4" GO: Biological Process GO:0098657 import into cell 3.36E-04 1.00E+00 6.71E-03 6.55E-02 21 54 "AGT,ATP1A1,ATP1A2,DRD1,GFAP,GLUL,GPM6B,KCNJ10,NAT8L,NOS1,SLC11A2,SLC1A3,SLC2A5,SLC8A2,SLC8A3,SNAP25,SNCA,TF,TRPM2,SLC38A1,SLC17A6" GO: Biological Process GO:0002790 peptide secretion 3.56E-04 1.00E+00 7.08E-03 6.92E-02 77 290 "ABAT,ADCY5,ADORA1,PLA2G6,LTBP4,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,RIMS2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,EPHA5,OGA,GABBR1,ILDR2,CPLX1,GCK,GLUL,GNAS,GPER1,PCLO,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYO5A,MYT1,NEUROD1,NNAT,NOS1,NUCB2,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,PTPRN,PTPRN2,RFX3,SMPD3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:0042551 neuron maturation 3.57E-04 1.00E+00 7.08E-03 6.92E-02 19 47 "APP,SPTBN4,ADGRB3,PICK1,CNTNAP2,DLG2,EDNRB,C1QL1,RND1,NRCAM,OPA1,RET,GLDN,LRRK2,KCNIP2,NFASC,CNTN2,MTCH1,LGI4" GO: Biological Process GO:0001932 regulation of protein phosphorylation 3.57E-04 1.00E+00 7.08E-03 6.92E-02 307 1404 "NDRG2,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,APC,ALS2,LRRC4C,APP,CDK10,MADD,SPTBN4,ZFYVE28,ARRB1,ARRB2,CAPRIN2,ATM,EIF4G3,RIPK1,BLM,KSR1,BMP7,CDK5R1,C5,CDK5R2,LDLRAD4,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CBS,CCK,CCNH,CCNT1,RGN,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,NOG,CRLF1,GPR37L1,SOCS6,TAOK2,SLIT2,CLU,FBXO7,MAP4K4,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,NCOR1,CLIP3,CSF1,CSF1R,SOCS5,CTNND1,MYADM,RASSF2,DCC,ZEB2,PARD6A,DMD,CDON,DRD1,ABI1,DUSP9,EDN1,EDN3,EDNRA,EDNRB,HIPK3,RASGRP1,CELSR3,EGFR,SORBS3,TENM1,TNK2,DMTN,EPHB1,ERBB2,ERBB4,DNAJC27,TLR7,PTK2B,TAOK3,RACK1,FKTN,STRADA,PRMT5,PPP1R1B,FECH,FER,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,FGR,PRKAG2,AGAP2,FOXM1,SEMA4D,FLT1,ZBED3,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,ZMYND11,ZNF274,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,PPARGC1A,MALT1,COPS8,GNAS,GNG3,PSRC1,GPER1,GPR37,RAPGEF1,C1QL4,GRIK2,GRM1,GRM5,PTPN5,MAP4K5,IRAK3,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HTR2A,MYLK2,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,INSM1,LRRTM3,LRRTM1,ITGAV,ITPKB,JAK2,KIT,LRRC4B,CAMK2N2,FGFBP3,PIK3AP1,MDFI,KITLG,MID1,DBNL,MT3,NELL1,NF1,NODAL,NOS1,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PAX6,PDE4D,PDGFRA,ENPP2,PDPK1,DUSP26,PIK3R1,PKD1,PLCL1,PPP1R1A,LRRN3,PPP5C,PRKAB2,PRKACB,PKIA,PRKAR1B,PRKCZ,MAPK3,MAPK7,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTK2,PTPRZ1,PPP2R3C,PID1,DUSP15,RET,RGS3,RGS4,KIRREL1,FBXW7,PRR5L,LRRK2,LRRTM4,FNIP1,TNFRSF19,PPP1R9A,PPM1E,MAGI3,ANKRD6,KDM4D,SIRT2,CDK5RAP3,CCDC88A,SLC11A1,MAPKBP1,SNCA,LMBRD1,SOX2,TNIK,DBNDD2,TSPYL2,LMO3,TAB2,PBLD,STOX1,SAMSN1,LRRC4,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,NSD1,TEK,TF,DICER1,SIRT1,LEFTY2,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PARD3,PIK3R5,IL34,NTSR2,TSC1,TSC2,UBC,UCHL1,FLRT2,FLRT1,MICAL1,VLDLR,WNT7A,RICTOR,NDRG4,WNK1,PMEPA1,MAP3K12,LRP8,RGMA,WNK3,WNK2,NELFE,VANGL2,SOCS4" GO: Biological Process GO:0055065 metal ion homeostasis 3.58E-04 1.00E+00 7.08E-03 6.92E-02 142 593 "ADCY5,ADCYAP1R1,ADORA1,ADORA2A,ADRA1D,ADRA1B,SLC24A4,AGT,PLA2G6,C1QTNF1,ANK1,ANK2,ANK3,ANXA7,APP,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CACNB4,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,RGN,CD38,SLC24A2,ABCG2,AKAP6,SLC25A27,AKAP5,CP,DBI,HEPH,FBXL5,SV2A,DLG4,DMD,DMPK,DRD1,FIS1,EDN1,EDN3,EDNRA,EDNRB,SGK2,EGFR,PTK2B,FECH,ATP13A4,NPTN,ATP2C1,OGA,JPH4,GALR1,DISC1,GCK,GNAS,GNG3,GPR12,MCHR1,GPER1,GRIK2,GRIN1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNA1,KCNH2,KCNJ10,KCNK3,KCNMA1,SFXN5,MT3,MYO5A,NOS1,SLC11A2,NUCB2,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,SLC25A23,PRKCB,CNNM2,PTH1R,PYGM,RAP1GDS1,KCTD17,RYR1,RYR3,S100B,SCN7A,SMPD3,SLC30A10,RASA3,SGK1,CLSTN1,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SNCA,TAC1,TACR1,TPCN2,ATP13A2,TF,SPX,TRPC1,TRPC3,TRPM2,SGK3,SLC30A3,SLC30A4,TMEM178A,TTC7A,SLC39A12,JPH3" GO: Biological Process GO:0023014 signal transduction by protein phosphorylation 3.65E-04 1.00E+00 7.20E-03 7.03E-02 218 962 "KCNH8,ACTN2,NDRG2,BRAP,ADORA1,ADRA1B,ADRB2,KIDINS220,AGT,TAOK1,C1QTNF1,C1QTNF3,ALK,SEMA7A,FGD2,MAP4K3,APC,CDK10,MADD,SPTBN4,ARRB1,ARRB2,RIPK1,FGF17,KSR1,BMP7,BMPR1B,C5,BTRC,DIRAS1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SPAG9,CBS,CCKBR,CD81,CDC42,CDH2,GPR37L1,TAOK2,MAP4K4,ARHGEF6,MAGED1,NRG2,NCOR1,CSF1R,CSF2RA,RASSF2,DCC,ZEB2,DLG4,DMD,CDON,DUSP9,EDN1,EDN3,EDNRA,HIPK3,RASGRP1,EGFR,RASA4,SORBS3,IRAK4,TENM1,EPHB1,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,FKTN,PRMT5,FGF1,FGF12,FGF13,FGF14,FGFR1,FGFR3,FOXM1,FLT1,WDR83,NPTN,CAMKK2,FYN,GAB1,CAB39,ZMYND11,ZNF274,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA1,GFRA2,GHR,GNG3,GPER1,GPR37,RAPGEF1,C1QL4,GRIK2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,PTPN5,MAP4K5,IRAK3,TNFAIP8L3,HMGB1,HMGCR,HTR2A,MYLK2,IGF1,IL6R,ITGAV,ITPKB,JAK1,JAK2,KCNH1,KCNH2,KIT,FGFBP3,SMAD1,PIK3AP1,MARK3,MDFI,SHC3,MEF2C,KITLG,MID1,PPM1L,DBNL,MT3,NCAM1,NEK1,NF1,NODAL,NTRK2,NTRK3,KSR2,OXTR,P2RX7,P2RY1,TREM2,PAK3,PDGFRA,DUSP26,MED1,PPP5C,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,DUSP15,RET,RGS3,RGS4,FBXW7,LRRK2,MAPK12,TNFRSF19,RASA3,MAGI3,ANKRD6,CDK5RAP3,SLC11A1,MAPKBP1,LMBRD1,SOX2,TNIK,DOK5,SPTAN1,SPTB,LMO3,TAB2,STOX1,ST5,MAPK8IP3,NEK4,FGD4,PLCB1,WWC1,FBXW11,TEK,TF,LEFTY2,TIAM1,TLR4,TNFRSF1B,PIK3R5,NR2C2,NTSR2,TSC2,UBC,UCHL1,WNT7A,NDRG4,MAP3K12,SCG2,WNK2,NELFE,PAK5,VANGL2" GO: Biological Process GO:0019935 cyclic-nucleotide-mediated signaling 3.66E-04 1.00E+00 7.20E-03 7.04E-02 26 73 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,KSR1,AKAP6,RIMS2,EDNRB,EPHA5,MRVI1,PTK2B,GNAS,PCLO,RAPGEF4,GUCY1B1,HTR5A,KCNC2,PDE2A,PDE3A,PDE3B,PDE4A,PDE4D,MAPK7,MGRN1,RASD2" GO: Biological Process GO:0045686 negative regulation of glial cell differentiation 3.69E-04 1.00E+00 7.25E-03 7.08E-02 14 30 "NOG,GPR37L1,DLX1,FGFR3,DLL3,NKX6-2,LINGO1,HES5,MBD1,MYCN,NF1,NTRK3,SIRT2,NR2E1" GO: Biological Process GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 3.70E-04 1.00E+00 7.25E-03 7.08E-02 45 150 "ADORA3,AGT,FGF17,CD86,NRG2,NCOR1,PPP1R16B,RASGRP1,EGFR,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FGR,AGAP2,SEMA4D,FLT1,STAMBP,FYN,GAB1,GPER1,IGF1,JAK2,KIT,PIK3AP1,KITLG,NTRK2,PDGFRA,SERPINE2,PIK3CD,PIK3R1,PLXNB1,PPP2R5C,MAPK3,RELN,PTK2,PTPN13,PRR5L,UNC5B,TEK,SIRT1,TSC2,UBE3A,VAV1" GO: Biological Process GO:0010927 cellular component assembly involved in morphogenesis 3.78E-04 1.00E+00 7.41E-03 7.24E-02 87 336 "ACTN2,TBC1D14,NME5,WDR35,CC2D2A,CEP126,ANK2,CNTNAP1,PRX,BBS2,CFLAR,MTMR2,HAP1,CAPN3,NEURL1,SEPT7,EVI5L,CFL2,CCDC151,TBPL1,TENM4,USP6NL,TBC1D5,KIAA0586,DMD,WDPCP,EDN1,CELSR3,ERCC2,TBC1D16,ZMYND10,TMEM107,DISC1,SEPT9,KIF3A,RABL2A,AGFG1,MAP4,MEF2C,POC1B,MYH3,MYH6,CCDC13,NEK1,OCRL,ODF2,PDGFRA,TMOD2,SNX10,PMP22,SPATA6,CEP41,HYDIN,PROX1,TMEM231,CEP97,CCDC40,RFX2,RFX3,RFX4,KCTD17,KIF27,FUZ,FHOD3,DZIP1,ABLIM3,IFT122,CLUAP1,NFASC,CLASP2,EPB41L3,TTBK2,PHLDB1,RPGRIP1L,CLASP1,OBSL1,DNAH7,DICER1,TMOD1,TPM1,UGT8,TBC1D15,TMEM237,EVI5,PCDH15,VANGL2,IFT88" GO: Biological Process GO:0034332 adherens junction organization 3.81E-04 1.00E+00 7.44E-03 7.27E-02 38 121 "ACTN1,ACTN2,EPB41L5,NUMB,CADM3,ARHGEF7,CDC42,CDH2,CDH8,CDH10,CDH18,NUMBL,TAOK2,NECTIN3,CTNND1,DAPK3,WDPCP,DMTN,PTK2B,DLC1,TESK2,SORBS1,FERMT2,GPM6B,ITGAV,LIMS1,AFDN,ENPP2,PDPK1,BCAS3,PTK2,RDX,CLASP2,CLASP1,TEK,TSC1,CADM1,CADM2" GO: Biological Process GO:0046434 organophosphate catabolic process 3.95E-04 1.00E+00 7.71E-03 7.53E-02 51 176 "ABHD6,AMPD3,OGT,APOC1,APOC2,PLA2G4C,PDE8B,SYNJ1,SYNJ2,MTMR2,MTMR7,SCARB1,ENTPD2,ENTPD4,NCOR1,GDA,PNPLA8,HDAC4,DRD1,ENPP6,GMPR2,RACK1,PRKAG2,INPP5K,GCK,PPARGC1A,GPD1,HTR2A,IGF1,INPP1,NCF2,OGG1,P2RX7,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,ASPDH,PPARA,MAPK7,SMPD3,SMUG1,NEIL2,PRTFDC1,NT5M" GO: Biological Process GO:0009179 purine ribonucleoside diphosphate metabolic process 4.07E-04 1.00E+00 7.87E-03 7.69E-02 33 101 "AK2,AMPD3,OGT,CASK,ENTPD2,TJP2,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,ENO2,PRKAG2,GCK,PPARGC1A,GPD1,HTR2A,IGF1,KHK,MPP2,OGDH,P2RX7,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,PKM,PPARA,HKDC1,MAGI3,OGDHL" GO: Biological Process GO:0009135 purine nucleoside diphosphate metabolic process 4.07E-04 1.00E+00 7.87E-03 7.69E-02 33 101 "AK2,AMPD3,OGT,CASK,ENTPD2,TJP2,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,ENO2,PRKAG2,GCK,PPARGC1A,GPD1,HTR2A,IGF1,KHK,MPP2,OGDH,P2RX7,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,PKM,PPARA,HKDC1,MAGI3,OGDHL" GO: Biological Process GO:0015711 organic anion transport 4.07E-04 1.00E+00 7.87E-03 7.69E-02 114 462 "ABAT,ADORA1,ADORA2A,AGT,OSBPL8,PLA2G6,ABCD2,PPFIA4,PPFIA2,PPFIA1,APOC1,APOC2,PPFIA3,SLC7A14,NCOA1,ATP1A2,SLC4A4,CA4,CA12,CACNA1A,CACNB4,CCK,SLC16A4,SCARB1,ASIC3,SLC22A6,SLC4A7,SLC4A8,SLC32A1,NCOR1,ABCG1,PITPNM3,PNPLA8,PITPNC1,DPYSL2,ABCC5,EDN1,MFSD10,SLC43A2,ACSL4,ATP8A1,PRKAG2,FOLR2,PRELID3A,GABBR1,ATP8A2,STARD10,CPLX1,GLS,GRIK1,NR3C1,GRM2,GRM7,MFSD2A,HBA1,HRH3,TNFAIP8L3,SLC6A17,KCNJ10,SFXN5,MTTP,MYO6,NF1,SLCO1C1,NTRK2,P2RX7,SLC10A4,SLC36A4,PPARA,PRKAB2,MAPK9,SLC26A11,SLC22A23,RAB3A,SLC6A15,ATP8B4,RXRA,SCP2,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,SLCO1A2,SLC22A4,RIMS1,SNAP25,SNCA,ATP10B,STX1A,STXBP1,SYT1,SLC37A2,ATP11A,ACSL6,SLC19A3,SPX,TRH,CA14,PITPNB,BEST1,SLC13A3,SLC26A10,SLC38A1,SLC17A7,SLC17A6,SLC4A10" GO: Biological Process GO:0043244 regulation of protein complex disassembly 4.08E-04 1.00E+00 7.87E-03 7.69E-02 32 97 "ACTN2,ADD1,ADD2,APC,SHROOM2,SPTBN4,ASPH,ARHGEF2,CFL2,DMTN,EPS8,APC2,FGF13,EVL,OGA,EML4,STMN2,GSN,IRAK3,SCIN,MID1,DBNL,TMOD2,RDX,MAP6D1,SLN,SPTAN1,SPTB,CLASP2,CLASP1,TMOD1,PLEKHH2" GO: Biological Process GO:0021697 cerebellar cortex formation 4.08E-04 1.00E+00 7.87E-03 7.69E-02 13 27 "ATP2B2,CACNA1A,CBLN1,NRXN1,WHRN,CEND1,KNDC1,NFIX,PROX1,ATXN2,FAIM2,AGTPBP1,WNT7A" GO: Biological Process GO:0006688 glycosphingolipid biosynthetic process 4.08E-04 1.00E+00 7.87E-03 7.69E-02 13 27 "ST3GAL5,LARGE1,GAL3ST1,ST8SIA3,ST3GAL6,ST6GALNAC3,B4GALNT1,ST8SIA5,ST6GALNAC6,ST3GAL3,ST8SIA1,UGT8,ST8SIA2" GO: Biological Process GO:0071526 semaphorin-plexin signaling pathway 4.20E-04 1.00E+00 8.07E-03 7.88E-02 16 37 "SEMA6A,SEMA7A,SEMA4G,ARHGDIA,NRP2,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" GO: Biological Process GO:0034260 negative regulation of GTPase activity 4.27E-04 1.00E+00 8.19E-03 8.00E-02 18 44 "ARRB1,ARRB2,RGN,DGKI,SLIT2,CPEB2,RASA4,TNK2,IQGAP2,FICD,IPO5,PLXNB3,BCAS3,PTPRN2,RDX,LRRK2,RTKN,AMOT" GO: Biological Process GO:0008064 regulation of actin polymerization or depolymerization 4.31E-04 1.00E+00 8.26E-03 8.07E-02 49 168 "ACTN2,ADD1,ADD2,SHROOM2,SPTBN4,WASF1,CFL2,SLIT2,PICK1,BAG4,MYADM,DBN1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,ARFIP1,CIT,GSN,NCKAP1L,SCIN,DBNL,PAK3,TMOD2,SSH1,MAGEL2,RDX,KIRREL1,AP1AR,PPP1R9A,FHOD3,SPTAN1,SPTB,KANK1,MLST8,TMOD1,PLEKHH2,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Biological Process GO:0007224 smoothened signaling pathway 4.34E-04 1.00E+00 8.29E-03 8.10E-02 40 130 "PTCHD1,DISP3,CC2D2A,PTCH2,CHRD,GPC2,BTRC,CFAP410,GPR37L1,BOC,KIAA0586,CDON,WDPCP,FGFR3,SALL3,GLI2,KIF3A,DISP2,HES5,NKX2-2,PAX6,SERPINE2,PRRX1,PRKACB,PTCH1,TMEM231,RFX4,KIF7,SALL1,FUZ,DZIP1,IFT122,CLUAP1,TROVE2,TTBK2,RPGRIP1L,GPR161,HHIP,ZIC1,IFT88" GO: Biological Process GO:0007017 microtubule-based process 4.38E-04 1.00E+00 8.35E-03 8.16E-02 155 658 "AP2A1,AP2A2,NME5,WDR35,CC2D2A,CEP126,KIF6,CDC42BPA,CNIH2,APC,APP,DNAH17,MARK4,DYNLL1,KIF1A,BBS2,CDK5R1,DST,HAP1,MAP7,PRC1,NEURL1,ARHGEF2,CDC42,CLTA,CLTC,CCDC151,CRMP1,NCOR1,GDA,CLIP3,ARHGEF10,KATNAL2,KIF26A,DCTN1,KIAA0753,BLOC1S6,KIF19,DNAH9,DYNC1I1,PDCD6IP,RASGRP1,EML1,TUBD1,ERBB2,APC2,KATNAL1,EYA1,TUBA1B,TUBB3,TUBB4A,ZMYND10,FER,FGF13,DCTN2,TACC2,TPPP3,BRSK1,NEK6,DISC1,TUBGCP4,TUBA8,MAP7D2,DCLK2,PSRC1,EML4,TUBA1C,STMN2,TPPP,KIF3A,DOCK7,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,KTN1,STMN1,MAP2,MAP4,MAP6,MAPT,MARK1,MID1,BLOC1S2,NEFH,CCDC13,DNHD1,NUMA1,OPA1,PAX6,CCSER2,PKD1,GPSM2,PTPA,PRKCZ,MAPK8,HYDIN,BCAS3,CNTLN,PTK2,SPDL1,PPP2R3C,CEP97,CCDC40,FIGN,RFX3,KIF7,MAP6D1,ATAT1,CLIP1,ATXN7,KIF27,SGK1,KIF21A,SH3GL2,KIF16B,SIRT2,CDK5RAP2,IFT122,SNCA,KIF13A,USP33,SON,KIF21B,CLUAP1,KIF1B,CLASP2,SS18,CEP68,PHLDB1,TACC1,MTCL1,CAMSAP2,CNTN2,CLASP1,OBSL1,DNAH7,DICER1,PARD3,TUBB2A,TUBB1,UCHL1,KLC2,XPO1,FMN2,SPIRE1,DNALI1,STMN4,TUBA1A,DNAH10,SLC39A12,IFT88,AP3B2" GO: Biological Process GO:0022011 myelination in peripheral nervous system 4.40E-04 1.00E+00 8.36E-03 8.16E-02 12 24 "PRX,ARHGEF10,LAMA2,ADAM22,NF1,FA2H,POU3F2,SH3TC2,SIRT2,DICER1,PARD3,LGI4" GO: Biological Process GO:0032878 regulation of establishment or maintenance of cell polarity 4.40E-04 1.00E+00 8.36E-03 8.16E-02 12 24 "SHTN1,KRIT1,WDPCP,PTK2B,RACK1,GSN,KIF3A,IGF1,BCAS3,KANK1,TEK,RICTOR" GO: Biological Process GO:0032292 peripheral nervous system axon ensheathment 4.40E-04 1.00E+00 8.36E-03 8.16E-02 12 24 "PRX,ARHGEF10,LAMA2,ADAM22,NF1,FA2H,POU3F2,SH3TC2,SIRT2,DICER1,PARD3,LGI4" GO: Biological Process GO:0045980 negative regulation of nucleotide metabolic process 4.49E-04 1.00E+00 8.47E-03 8.27E-02 25 70 "APLP1,AKAP6,AKAP5,HDAC4,EDN1,EDNRA,EDNRB,GABBR1,GALR1,PPARGC1A,GRM2,GRM3,GRM7,GRM8,HRH3,HPCA,P2RY13,NUCB2,OPRL1,PALM,PDE2A,PPARA,MAPK7,PID1,SNCA" GO: Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 4.49E-04 1.00E+00 8.47E-03 8.27E-02 25 70 "ADORA3,AGT,ERBB2,ERBB4,FGFR1,FGR,AGAP2,SEMA4D,FLT1,FYN,GPER1,IGF1,JAK2,KIT,PIK3AP1,NTRK2,PDGFRA,PLXNB1,RELN,PTK2,PRR5L,UNC5B,TEK,SIRT1,UBE3A" GO: Biological Process GO:0030041 actin filament polymerization 4.50E-04 1.00E+00 8.47E-03 8.27E-02 48 164 "ADD1,ADD2,GAS7,SPTBN4,WASF1,SLIT2,PICK1,BAG4,MYADM,DBN1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,WASF3,ARFIP1,GSN,NCKAP1L,SCIN,JAK2,DBNL,PAK3,TMOD2,MAGEL2,RDX,KIRREL1,AP1AR,PPP1R9A,FHOD3,TTC17,SPTAN1,SPTB,KANK1,COBL,MLST8,TMOD1,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Biological Process GO:0034391 regulation of smooth muscle cell apoptotic process 4.52E-04 1.00E+00 8.47E-03 8.27E-02 10 18 "RBM10,ARRB1,ARRB2,EDN1,APOPT1,IGF1,RBPJ,IL12A,PDE1A,SIRT1" GO: Biological Process GO:0034390 smooth muscle cell apoptotic process 4.52E-04 1.00E+00 8.47E-03 8.27E-02 10 18 "RBM10,ARRB1,ARRB2,EDN1,APOPT1,IGF1,RBPJ,IL12A,PDE1A,SIRT1" GO: Biological Process GO:0055119 relaxation of cardiac muscle 4.52E-04 1.00E+00 8.47E-03 8.27E-02 10 18 "ATP1A1,ATP1A2,ATP2A2,CAMK2D,CAMK2G,CHGA,AKAP6,PDE4B,PDE4D,SLC8A1" GO: Biological Process GO:0048488 synaptic vesicle endocytosis 4.58E-04 1.00E+00 8.58E-03 8.38E-02 11 21 "AMPH,SYNJ1,CANX,OPHN1,PACSIN1,ITSN1,SH3GL2,NLGN1,SNCA,SYT1,SYT5" GO: Biological Process GO:0051480 regulation of cytosolic calcium ion concentration 4.64E-04 1.00E+00 8.67E-03 8.47E-02 80 306 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,AGT,PLA2G6,C1QTNF1,ANK2,ASPH,ATP1A2,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CALB1,CALB2,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,CD38,AKAP6,AKAP5,DBI,DLG4,DMD,DRD1,FIS1,EDN1,EDNRA,EDNRB,PTK2B,NPTN,OGA,JPH4,GALR1,GCK,GNG3,MCHR1,GPER1,GRM1,HRH3,HMGB1,HTR2A,IL6ST,ITGAV,JAK2,SLC35G1,KCNK3,MYO5A,NOS1,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,FXYD1,PTH1R,RYR1,RYR3,SMPD3,RASA3,SLC8A2,SLC8A1,SLC8A3,SNCA,TAC1,TACR1,TPCN2,TRPC1,TRPC3,TRPM2,TMEM178A,JPH3" GO: Biological Process GO:0045761 regulation of adenylate cyclase activity 4.66E-04 1.00E+00 8.69E-03 8.49E-02 26 74 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,CALM1,AKAP5,DRD1,EDNRA,EDNRB,CAP2,GABBR1,GALR1,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,HRH3,HPCA,P2RY13,NF1,PALM,VIPR2" GO: Biological Process GO:0007167 enzyme linked receptor protein signaling pathway 4.80E-04 1.00E+00 8.94E-03 8.73E-02 228 1016 "ADORA1,ADRB2,AP2A1,AP2A2,AGT,OSBPL8,LTBP4,ALK,OGT,DGKD,APP,ZFYVE28,ARRB2,CHRD,RASL11B,ATP6V1G2,ATP6V0A1,FGF17,NRP2,BMP7,BMPR1B,CDK5R1,ARHGEF7,BTK,LDLRAD4,DDR1,KALRN,HAP1,NEURL1,REPS2,CDC42,NOG,CHN1,EPS15L1,ZFYVE9,STOML1,CLTA,NGEF,AKAP7,COL4A5,NRG2,CSF1,CSF1R,SIPA1L1,SOCS5,APPL1,PHF14,CYBB,ZFYVE16,RASSF2,ELMO1,MAGI2,PARD6A,CHRDL1,DNM1,DNM2,ABI1,EFNA2,EFNA3,EFNB3,APH1A,EGFR,PLEKHA1,TNK2,EPHA5,EPHB1,EPS8,ERBB2,ERBB4,ECSIT,F3,PTK2B,EFEMP1,FER,FGF1,FGF12,FGF14,FGFR1,FGFR3,BAIAP2,FGR,FLT1,AKAP3,SORBS1,NPTN,ATP6V1H,NRG3,FYN,DKK3,GAB1,NCKAP1,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA1,GFRA2,GHR,FERMT2,GPER1,GRB10,RAPGEF1,GRIN1,PTPRT,RNF165,ATOH8,NCKAP1L,HSP90AA1,IGF1,IGFBP1,RBPJ,HES5,IL6ST,ITGAV,JAK1,JAK2,KIT,LIFR,FGFBP3,SMAD1,SMAD9,ZFYVE27,MATK,SHC3,PPM1L,GIT1,MT3,MYH6,HNRNPM,NBL1,NCF2,NODAL,VWA2,NPPA,NPR2,NTRK2,NTRK3,DDR2,NUCB2,PAK3,PDGFRA,PDPK1,PIK3C2A,PIK3R1,EPN1,SCHIP1,PILRA,SH3KBP1,POLR2F,SKOR1,PRKCB,PRKCZ,MAPK3,PTK2,PTN,PTPRD,PTPRE,PTPRG,PID1,SH3TC2,FAT4,DUSP15,RET,RPE65,TMEM100,EPHA10,FBXW7,MAPK12,ATXN1,ATXN7,ITSN1,SH3GL2,KIF16B,FUZ,SHC4,SIRT2,ELMO2,SNCA,MBD5,LMBRD1,SOX11,DOK5,PEG10,ZNF423,SPART,PBLD,CLASP2,SS18,ERBIN,KANK1,SULF2,PLCB1,VWC2,TCF4,TCF7L2,ZEB1,TEK,TF,SIRT1,LEFTY2,TGFBR3,ZNF106,HHIP,TIAM1,PARD3,RBFOX2,RGMB,TRIO,STXBP4,TRPS1,TSC1,TSC2,UBC,FLRT2,FLRT1,VAV1,VAV2,ZIC2,ATP6V0E2,NDRG4,CRB2,ZFAND5,PMEPA1,RGMA,MVB12B,IFT88,SOCS4" GO: Biological Process GO:0006898 receptor-mediated endocytosis 4.87E-04 1.00E+00 9.02E-03 8.81E-02 81 311 "ACHE,ADRB2,AP2A1,AP2A2,AMPH,APOC1,APOC2,ARRB1,ARRB2,ASGR1,SYNJ1,MTMR2,CANX,HIP1R,SCARB1,CD81,CLTA,CLTB,CLTC,PICK1,TBC1D5,DNAJC6,MAGI2,SNAP91,DLG4,DNM1,DNM2,TNK2,CALCRL,RABEPK,FCGR1A,FCGR1B,SCARA3,SGIP1,FOLR2,HHIPL1,GHR,LOXL3,GRK4,GRIA1,GRIA2,KIF3A,PTPN5,HBA1,PACSIN2,HNRNPK,HP,HPR,HSP90AA1,SMAP1,LRRTM1,LDLRAD3,LRP1B,DBNL,MSR1,CLEC9A,OLR1,OPHN1,ENPP2,NLGN3,LRP12,PACSIN1,MAPK3,MASP1,ATXN2,ITSN1,SH3GL2,NLGN1,SNCA,LMBRD1,FCHO1,MLC1,SYT1,SYT5,CNTN2,SYNE1,TF,PARD3,TMPRSS5,VLDLR,LRP8" GO: Biological Process GO:0009154 purine ribonucleotide catabolic process 4.87E-04 1.00E+00 9.02E-03 8.81E-02 15 34 "AMPD3,PDE8B,GMPR2,RACK1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,MAPK7,PRTFDC1" GO: Biological Process GO:0001941 postsynaptic membrane organization 4.87E-04 1.00E+00 9.02E-03 8.81E-02 15 34 "CDH2,NRXN1,NRXN2,DBN1,MAGI2,DLG4,GPHN,GLRB,NLGN3,RELN,PTN,LRRTM4,NLGN1,LRRC4,ZMYND8" GO: Biological Process GO:0009185 ribonucleoside diphosphate metabolic process 4.91E-04 1.00E+00 9.08E-03 8.87E-02 34 106 "AK2,AMPD3,OGT,CASK,ENTPD2,TJP2,ENTPD4,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,ENO2,PRKAG2,GCK,PPARGC1A,GPD1,HTR2A,IGF1,KHK,MPP2,OGDH,P2RX7,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,PKM,PPARA,HKDC1,MAGI3,OGDHL" GO: Biological Process GO:0030832 regulation of actin filament length 5.01E-04 1.00E+00 9.18E-03 8.96E-02 49 169 "ACTN2,ADD1,ADD2,SHROOM2,SPTBN4,WASF1,CFL2,SLIT2,PICK1,BAG4,MYADM,DBN1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,ARFIP1,CIT,GSN,NCKAP1L,SCIN,DBNL,PAK3,TMOD2,SSH1,MAGEL2,RDX,KIRREL1,AP1AR,PPP1R9A,FHOD3,SPTAN1,SPTB,KANK1,MLST8,TMOD1,PLEKHH2,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Biological Process GO:0000165 MAPK cascade 5.02E-04 1.00E+00 9.18E-03 8.96E-02 210 928 "ACTN2,NDRG2,BRAP,ADORA1,ADRA1B,ADRB2,KIDINS220,AGT,TAOK1,C1QTNF1,C1QTNF3,ALK,SEMA7A,FGD2,MAP4K3,APC,CDK10,MADD,SPTBN4,ARRB1,ARRB2,RIPK1,FGF17,KSR1,BMP7,C5,BTRC,DIRAS1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SPAG9,CBS,CCKBR,CD81,CDC42,CDH2,GPR37L1,TAOK2,MAP4K4,ARHGEF6,MAGED1,NRG2,NCOR1,CSF1R,CSF2RA,RASSF2,DCC,ZEB2,DLG4,DMD,CDON,DUSP9,EDN1,EDN3,EDNRA,HIPK3,RASGRP1,EGFR,RASA4,SORBS3,IRAK4,TENM1,EPHB1,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,FKTN,PRMT5,FGF1,FGF12,FGF13,FGF14,FGFR1,FGFR3,FOXM1,FLT1,WDR83,NPTN,CAMKK2,FYN,GAB1,ZMYND11,ZNF274,INPP5K,GCNT2,GDF1,MSTN,GDF9,GFRA1,GFRA2,GHR,GNG3,GPER1,GPR37,RAPGEF1,C1QL4,GRIK2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,PTPN5,MAP4K5,IRAK3,TNFAIP8L3,HMGB1,HMGCR,HTR2A,MYLK2,IGF1,IL6R,ITGAV,ITPKB,JAK1,JAK2,KIT,FGFBP3,SMAD1,PIK3AP1,MARK3,MDFI,SHC3,MEF2C,KITLG,MID1,PPM1L,DBNL,MT3,NCAM1,NF1,NODAL,NTRK2,NTRK3,KSR2,OXTR,P2RX7,P2RY1,TREM2,PAK3,PDGFRA,DUSP26,MED1,PPP5C,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,DIRAS2,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,DUSP15,RET,RGS3,RGS4,FBXW7,LRRK2,MAPK12,TNFRSF19,RASA3,MAGI3,ANKRD6,CDK5RAP3,SLC11A1,MAPKBP1,LMBRD1,SOX2,TNIK,DOK5,SPTAN1,SPTB,LMO3,TAB2,STOX1,ST5,MAPK8IP3,FGD4,PLCB1,WWC1,FBXW11,TEK,TF,LEFTY2,TIAM1,TLR4,TNFRSF1B,PIK3R5,NR2C2,NTSR2,TSC2,UBC,UCHL1,WNT7A,NDRG4,MAP3K12,SCG2,WNK2,NELFE,VANGL2" GO: Biological Process GO:0016188 synaptic vesicle maturation 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "CLCN3,DLG4,ZDHHC15,RAB3A,STXBP1,SYP,SLC17A7" GO: Biological Process GO:0021707 cerebellar granule cell differentiation 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "ATP2B2,CBLN1,NRXN1,KNDC1,NFIX,PROX1,WNT7A" GO: Biological Process GO:0043653 mitochondrial fragmentation involved in apoptotic process 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "CCAR2,DNM1L,FIS1,ERBB4,NPTX1,PPP2R2B,MFF" GO: Biological Process GO:0021684 cerebellar granular layer formation 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "ATP2B2,CBLN1,NRXN1,KNDC1,NFIX,PROX1,WNT7A" GO: Biological Process GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "SLIT2,FGFR1,OGDH,ROBO1,LRRK2,ARX,SLIT1" GO: Biological Process GO:1901841 regulation of high voltage-gated calcium channel activity 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "CACNA2D1,CACNB2,CALM1,NOS1AP,FGF14,NPPA,PDE4B" GO: Biological Process GO:0014052 regulation of gamma-aminobutyric acid secretion 5.05E-04 1.00E+00 9.18E-03 8.96E-02 7 10 "ABAT,GABBR1,GRIK1,HRH3,P2RX7,SLC6A1,TRH" GO: Biological Process GO:0045834 positive regulation of lipid metabolic process 5.09E-04 1.00E+00 9.22E-03 9.00E-02 45 152 "ABHD6,ADRB2,AGT,DISP3,PLA2G6,ADGRF5,ABCD2,GPAM,APOC1,APOC2,RGN,SCARB1,CD81,CDC42,ABCG1,DBI,CCDC3,EEF1A2,SH3GLB1,ERBB4,PTK2B,RACK1,FGF1,FGFR3,FGR,FLT1,SORBS1,PPARGC1A,TNFAIP8L3,HTR2A,IGF1,KIT,NUCB2,PC,PDGFRA,PPARA,MAPK9,PTK2,SCP2,SMPD3,AMBRA1,ACSL6,TCF7L2,TEK,VAV2" GO: Biological Process GO:0030100 regulation of endocytosis 5.14E-04 1.00E+00 9.31E-03 9.09E-02 62 226 "ABR,ADD1,BIN1,APOC1,APOC2,ARRB1,ARRB2,SYNJ1,MTMR2,SCARB1,PICK1,CLIP3,CALY,RUBCN,SNPH,ZFYVE16,TBC1D5,SIRPA,DNAJC6,MAGI2,SNAP91,DLG4,DNM2,DOCK2,TNK2,SIRPB1,RACK1,FCGR1A,FGR,MEX3B,ANKFY1,SGIP1,STON1,KIF3A,PTPN5,PACSIN2,NCKAP1L,HMGB1,HNRNPK,SMAP1,LRRTM1,ITGAV,SCAMP5,OPHN1,PACSIN1,PRKCG,PTK2,PTX3,RAB5B,RAP1GAP,ATXN2,SH3GL2,NLGN1,EPN2,SLC11A1,ARFGAP1,SNCA,SYNE1,TF,PARD3,TSC2,TUB" GO: Biological Process GO:0032272 negative regulation of protein polymerization 5.23E-04 1.00E+00 9.44E-03 9.22E-02 23 63 "ADD1,ADD2,SPTBN4,SLIT2,CLIP3,MYADM,DMTN,EPS8,EVL,STMN2,GSN,SCIN,STMN1,DBNL,TMOD2,RDX,SGK1,FHOD3,SNCA,SPTAN1,SPTB,KANK1,TMOD1" GO: Biological Process GO:0071417 cellular response to organonitrogen compound 5.27E-04 1.00E+00 9.50E-03 9.28E-02 125 517 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,AGT,OSBPL8,OGT,APLP1,GPAM,APP,ATP6V1G2,ATP6V0A1,HCN2,BLM,CAMK2A,NEURL1,ARHGEF2,SLIT2,AKAP7,AKAP6,AKAP5,CPS1,CRHBP,APPL1,HDAC9,DNM2,CPEB2,DRD1,EDN1,EGFR,DMTN,RRAGB,FER,BAIAP2,FOLR2,SORBS1,ATP6V1H,FYN,GAB1,GABRA1,GABRB1,GABRB3,GABRG2,AHCYL1,INPP5K,GCK,MSTN,SESN1,GHR,PPARGC1A,GNAS,GNG3,GNG4,GPD1,GPER1,GRB10,RAPGEF1,HNRNPK,IGF1,IGFBP1,JAK2,KCNJ11,IPO5,MEF2C,SESN3,MYO5A,VWA2,NOS1,HCN1,NTRK2,NUCB2,TREM2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDGFRA,PDPK1,GPR173,GNG2,PENK,SSH1,PIK3C2A,PIK3R1,PRKACB,PRKAR1B,PRKCB,PRKCZ,MAPK3,PTAFR,PTK2,PTPRE,CASTOR1,PID1,RNASEL,RPE65,LRRK2,RXRA,RYR1,RYR3,SGK1,CPEB3,SLC8A1,SLC8A3,SIRT2,CPEB4,SNCA,MBD5,LMBRD1,WDTC1,SSTR1,SSTR2,KANK1,PLCB1,ZEB1,SIRT1,ZNF106,STXBP4,TSC1,TSC2,VLDLR,P2RY12,ATP6V0E2" GO: Biological Process GO:0001934 positive regulation of protein phosphorylation 5.47E-04 1.00E+00 9.85E-03 9.62E-02 216 959 "ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADRA1B,ADRB2,KIDINS220,AGT,OSBPL8,PLA2G6,TAOK1,C1QTNF1,C1QTNF3,BCAR3,ALK,OGT,SEMA7A,FGD2,MAP4K3,ALS2,CDK10,MADD,ARRB1,ARRB2,CAPRIN2,ATM,EIF4G3,RIPK1,KSR1,BMP7,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,CAMK2D,SPAG9,CCK,CCNH,CCNT1,NEURL1,CD81,ARHGEF2,CDC25B,CDC42,CDH2,CRLF1,GPR37L1,TAOK2,CLU,CNTN1,AKAP6,AKAP5,MAGED1,BAG4,CLIP3,CSF1,CSF1R,CTNND1,RASSF2,DCC,ZEB2,CDON,ABI1,DUSP9,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,EGFR,SORBS3,TENM1,TNK2,ERBB2,ERBB4,DNAJC27,PTK2B,TAOK3,RACK1,STRADA,FGF1,FGF13,FGFR1,FGFR3,MAD2L2,PRKAG2,AGAP2,SEMA4D,FLT1,NPTN,CAMKK2,NRG3,FYN,GAB1,CAB39,GCNT2,GDF1,MSTN,GDF9,GFRA2,GHR,MALT1,COPS8,GNAS,GNG3,PSRC1,GPER1,GPR37,RAPGEF1,GRM1,GRM5,PTPN5,MAP4K5,NCKAP1L,TNFAIP8L3,HMGB1,HMGCR,HTR2A,IGF1,DOCK7,KNDC1,HES5,IL6R,IL6ST,IL12A,ITGAV,JAK2,KIT,FGFBP3,MDFI,KITLG,MID1,DBNL,MT3,NELL1,NODAL,NTRK2,NTRK3,DDR2,KSR2,OPRL1,P2RX7,P2RY1,TREM2,PAK3,PDGFRA,ENPP2,PDPK1,PIK3R1,PKD1,LRRN3,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK9,MAPK10,DIRAS2,PROX1,RELN,PTK2,PTPRZ1,PPP2R3C,DUSP15,RET,FBXW7,PRR5L,LRRK2,FNIP1,TNFRSF19,PPP1R9A,MAGI3,ANKRD6,CCDC88A,SLC11A1,MAPKBP1,SNCA,SOX2,TNIK,TAB2,STOX1,ST5,MAPK8IP3,MPRIP,FGD4,PLCB1,MLST8,WWC1,TEK,TF,SIRT1,LEFTY2,AKTIP,THBS4,TIAM1,TLR4,ZFP91,TNFRSF1B,PIK3R5,IL34,NTSR2,UBC,VLDLR,WNT7A,RICTOR,NDRG4,MAP3K12,LRP8,RGMA,WNK3,NELFE,VANGL2" GO: Biological Process GO:1901381 positive regulation of potassium ion transmembrane transport 5.60E-04 1.00E+00 1.01E-02 9.82E-02 14 31 "ACTN2,ANK2,ATP1B3,AKAP7,AKAP6,NOS1AP,DNM2,DPP6,EDN3,KCNC1,KCNC2,KCNH2,NPPA,KCNE5" GO: Biological Process GO:0051937 catecholamine transport 5.73E-04 1.00E+00 1.03E-02 1.00E-01 25 71 "ABAT,ADORA2A,AGT,CADPS,CHGA,CHRNA4,CHRNB2,CNR1,DRD1,GABBR1,GCK,HRH3,HTR2A,KCNA2,KCNB1,NAT8L,OXTR,P2RY1,PLCD1,PRKCB,SMPD3,SNCA,STX1A,P2RY12,RTN4" GO: Biological Process GO:0043551 regulation of phosphatidylinositol 3-kinase activity 5.90E-04 1.00E+00 1.06E-02 1.03E-01 18 45 "CCKBR,CDC42,RUBCN,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,KIT,PDGFRA,PIK3R1,PTK2,AMBRA1,TEK,PIK3R5,VAV2" GO: Biological Process GO:0009166 nucleotide catabolic process 5.95E-04 1.00E+00 1.06E-02 1.04E-01 34 107 "AMPD3,OGT,PDE8B,ENTPD4,NCOR1,GDA,HDAC4,GMPR2,RACK1,PRKAG2,GCK,PPARGC1A,GPD1,HTR2A,IGF1,NCF2,OGG1,P2RX7,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ASPDH,PPARA,MAPK7,SMUG1,NEIL2,PRTFDC1,NT5M" GO: Biological Process GO:0021695 cerebellar cortex development 5.98E-04 1.00E+00 1.06E-02 1.04E-01 21 56 "ATP2B2,CACNA1A,CBLN1,NRXN1,WHRN,SEZ6L2,SEZ6,CEND1,GLI2,KNDC1,NEUROD2,NFIX,OGDH,SERPINE2,PROX1,RFX4,ATXN2,FAIM2,AGTPBP1,SEZ6L,WNT7A" GO: Biological Process GO:0001755 neural crest cell migration 5.98E-04 1.00E+00 1.06E-02 1.04E-01 21 56 "SEMA6A,SEMA7A,SEMA4G,NRP2,ZEB2,EDN3,EDNRB,SEMA3D,ERBB4,SEMA6C,SEMA4D,GBX2,KITLG,PAX6,SEMA5B,RET,SOX8,SEMA6D,SOX10,SEMA4A,SEMA3B" GO: Biological Process GO:0044070 regulation of anion transport 6.07E-04 1.00E+00 1.08E-02 1.05E-01 48 166 "TTYH1,ABAT,ADORA1,ADORA2A,AGT,PLA2G6,ATP1A2,RIPK1,CACNA1A,CCK,CHRNA4,CHRNB2,CLCN3,CLCN4,CNR1,CRY2,NCOR1,TCAF1,DPYSL2,DRD1,EDN1,ACSL4,ATP8A1,GABBR1,AHCYL1,ATP8A2,GPM6B,GRIK1,NR3C1,GRM7,HRH3,HTR2A,KCNA2,NAT8L,MAOB,NOS1,P2RX7,FXYD1,PRKCB,MAPK9,PTAFR,SLC6A1,RAB3GAP1,SNCA,ACSL6,LRRC8A,TRH,RTN4" GO: Biological Process GO:0010038 response to metal ion 6.21E-04 1.00E+00 1.10E-02 1.08E-01 92 364 "CPNE2,ABAT,ALAD,ANK3,ANXA7,APBB1,GPAM,APP,ASCL1,ASPH,CACNA1G,CALM1,CAMK2B,CAMK2D,CAPN3,CD86,ENTPD6,CPNE6,CLU,ABCG2,CNGA3,CP,CPS1,CRHBP,EDN1,EGFR,RASA4,DMTN,RASGRP2,KCNMB2,ADGRV1,PTK2B,FECH,SYT3,HVCN1,AHCYL1,GATM,PPARGC1A,KCNMB4,GRIN1,GSN,HSD17B1,ITPKB,KCNA1,KCNC1,KCNC2,KCNH1,KCNK3,KCNMA1,KHK,LIG4,MAOB,MBP,MEF2C,MT1M,MT3,NCAM1,NEUROD2,NOS1,NPTX1,SLC11A2,HCN1,OGG1,P2RX7,PDE1C,PENK,PGAM2,PLCD1,SLC25A23,PPP3CA,PPP5C,MAPK8,MAPK9,QDPR,CARF,LRRK2,KCNIP2,RYR3,SLC30A10,SEC31A,SLC6A1,SNCA,ABCC8,SYT1,ATP13A2,TF,TRPC1,TRPC3,XRCC4,SLC30A3,SLC30A4,PCDH15" GO: Biological Process GO:0007266 Rho protein signal transduction 6.34E-04 1.00E+00 1.12E-02 1.09E-01 47 162 "ABR,PLEKHG5,ADRA1B,FGD2,ALS2,SHTN1,ARHGAP5,ARHGDIA,ARHGDIG,ARRB1,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,CDH2,ADGRG1,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,ARHGAP32,TIAM2,EDNRA,DLC1,BAIAP2,RASGRF1,RASGRF2,ARHGEF10L,ROBO1,RTKN,ITSN1,PREX2,ARHGEF40,MCF2L2,KANK1,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,VANGL2,SPATA13" GO: Biological Process GO:0014044 Schwann cell development 6.35E-04 1.00E+00 1.12E-02 1.09E-01 13 28 "PRX,ARHGEF10,MED12,LAMA2,ADAM22,NF1,FA2H,POU3F2,SH3TC2,SIRT2,DICER1,PARD3,LGI4" GO: Biological Process GO:0051647 nucleus localization 6.35E-04 1.00E+00 1.12E-02 1.09E-01 13 28 "CDC42BPA,CDC42,DMD,DCTN4,KIAA1109,TACC2,DOCK7,PAX6,PTK2,SLIT1,SYNE2,TACC1,SYNE1" GO: Biological Process GO:0001504 neurotransmitter uptake 6.35E-04 1.00E+00 1.12E-02 1.09E-01 13 28 "ATP1A2,DRD1,GFAP,GLUL,GPM6B,KCNJ10,NAT8L,NOS1,SLC1A3,SNAP25,SNCA,SLC38A1,SLC17A6" GO: Biological Process GO:0045956 positive regulation of calcium ion-dependent exocytosis 6.35E-04 1.00E+00 1.12E-02 1.09E-01 13 28 "CADPS,CACNA1I,CACNA1G,CDK5R2,KCNB1,SYT9,SCAMP5,NLGN1,RIMS1,STX1A,STXBP1,PLCB1,SYT1" GO: Biological Process GO:0050796 regulation of insulin secretion 6.55E-04 1.00E+00 1.15E-02 1.12E-01 55 197 "ABAT,ADCY5,PLA2G6,ARNTL,ARRB1,PDE8B,CACNA1A,CACNA1D,CACNA1E,BRSK2,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,C2CD2L,SIDT2,EPHA5,OGA,GCK,GLUL,GNAS,GPER1,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYT1,NEUROD1,NNAT,NOS1,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,RFX3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VSNL1" GO: Biological Process GO:0045860 positive regulation of protein kinase activity 6.56E-04 1.00E+00 1.15E-02 1.12E-01 120 496 "ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,ADORA1,ADRB2,KIDINS220,AGT,OSBPL8,TAOK1,ALK,FGD2,MAP4K3,ALS2,MADD,ARRB1,RIPK1,CDK5R1,C5,CDK5R2,MMD2,DIRAS1,CALM1,SPAG9,CCNH,CCNT1,NEURL1,CD81,CDC25B,TAOK2,CLU,AKAP6,MAGED1,CSF1,CSF1R,RASSF2,ZEB2,ABI1,DUSP9,EDN1,EDN3,RASGRP1,EGFR,TENM1,ERBB2,PTK2B,TAOK3,STRADA,FGF1,FGF13,FGFR1,PRKAG2,AGAP2,FLT1,CAMKK2,NRG3,GAB1,CAB39,GHR,MALT1,COPS8,GNG3,PSRC1,RAPGEF1,GRM1,GRM5,MAP4K5,NCKAP1L,HMGB1,HTR2A,IGF1,IL6R,JAK2,KIT,MDFI,KITLG,DBNL,MT3,NELL1,NTRK3,DDR2,P2RX7,PAK3,PDPK1,PKD1,PRKACB,PRKAR1B,PRKCZ,MAPK3,MAPK10,DIRAS2,PROX1,RELN,PTK2,PPP2R3C,FBXW7,LRRK2,PPP1R9A,MAGI3,CCDC88A,SLC11A1,MAPKBP1,SNCA,TNIK,TAB2,STOX1,MAPK8IP3,FGD4,TF,SIRT1,TIAM1,TLR4,ZFP91,PIK3R5,UBC,VLDLR,MAP3K12,LRP8,VANGL2" GO: Biological Process GO:0055067 monovalent inorganic cation homeostasis 6.63E-04 1.00E+00 1.16E-02 1.13E-01 46 158 "SLC12A5,ADORA1,ADORA2A,AGT,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP6V1G2,ATP6V0A1,CA4,CA12,CAMK2D,CLCN3,SLC4A7,SLC4A8,EDN1,EDNRB,SGK2,TMEM175,ATP6V1H,GNAS,KCNH2,KCNJ10,KCNMA1,AQP11,RAB39A,SLC26A11,LRRK2,SCN7A,SGK1,SLC4A3,SLC8A1,SLC9A5,SLC11A1,TAC1,TACR1,SPX,CA14,TTPA,SGK3,ATP6V0E2,SLC26A10,SLC17A7,SLC4A10" GO: Biological Process GO:0018105 peptidyl-serine phosphorylation 6.69E-04 1.00E+00 1.17E-02 1.14E-01 70 264 "CDC7,AGT,BCAR3,OGT,SPTBN4,ARRB1,ARRB2,CAPRIN2,ATM,RIPK1,CDK5R1,CAMK2A,CAMK2B,CAMK2D,BRSK2,CDC42,DCLK1,BAG4,CSNK1E,CSNK1G3,RASSF2,DMD,DMPK,DYRK1A,SGK2,HIPK3,TENM1,DMTN,RACK1,MAD2L2,BRSK1,CAB39,NEK6,INPP5K,GFRA2,TTBK1,DCLK2,DOCK7,STK32C,NOS1,NTRK2,NTRK3,PDE4D,PDPK1,PKD1,PLCL1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK7,MAPK8,STK32A,RET,RPS6KA2,STK32B,LRRK2,MAPK12,FNIP1,SGK1,MAST1,SNCA,STOX1,TTBK2,NSD1,TEK,SGK3,RICTOR,MAP3K12" GO: Biological Process GO:0048505 regulation of timing of cell differentiation 6.93E-04 1.00E+00 1.21E-02 1.18E-01 8 13 "ASCL1,RBPJ,NODAL,PAX6,SERPINE2,SOX5,NR2E1,GDPD5" GO: Biological Process GO:0032890 regulation of organic acid transport 7.04E-04 1.00E+00 1.22E-02 1.20E-01 24 68 "ABAT,ADORA1,ADORA2A,AGT,PLA2G6,ATP1A2,CCK,NCOR1,DPYSL2,EDN1,ACSL4,GABBR1,GRIK1,NR3C1,GRM7,HRH3,P2RX7,FXYD1,MAPK9,SLC6A1,RAB3GAP1,SNCA,ACSL6,TRH" GO: Biological Process GO:0032892 positive regulation of organic acid transport 7.09E-04 1.00E+00 1.22E-02 1.20E-01 17 42 "ABAT,ADORA2A,AGT,PLA2G6,CCK,DPYSL2,EDN1,GABBR1,GRIK1,NR3C1,P2RX7,FXYD1,MAPK9,SLC6A1,RAB3GAP1,ACSL6,TRH" GO: Biological Process GO:0014014 negative regulation of gliogenesis 7.09E-04 1.00E+00 1.22E-02 1.20E-01 17 42 "NOG,GPR37L1,DLX1,FGFR3,DLL3,NKX6-2,LINGO1,HES5,MBD1,MYCN,NF1,NTRK3,PTN,SIRT2,SOX11,DICER1,NR2E1" GO: Biological Process GO:0060122 inner ear receptor cell stereocilium organization 7.09E-04 1.00E+00 1.22E-02 1.20E-01 15 35 "ATP2B2,WHRN,USH1C,ADGRV1,SEC24B,CECR2,KIF3A,HES5,MYO7A,STRC,FAT4,HEY1,PCDH15,VANGL2,IFT88" GO: Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 7.09E-04 1.00E+00 1.22E-02 1.20E-01 15 35 "ADORA2A,DGKZ,DGKD,CCK,DGKI,CHRM1,PICK1,DGKB,DGKG,EDN1,EDNRA,GAP43,GRM1,GRM5,PARD3" GO: Biological Process GO:0043113 receptor clustering 7.29E-04 1.00E+00 1.25E-02 1.23E-01 20 53 "CACNA1A,CDH2,NRXN1,NRXN2,PICK1,MAGI2,DLG2,DLG3,DLG4,GPHN,GLRB,GRIK2,GRIK5,GSN,RELN,PTN,LRRTM4,NLGN1,IFT122,ARHGEF9" GO: Biological Process GO:0043550 regulation of lipid kinase activity 7.29E-04 1.00E+00 1.25E-02 1.23E-01 20 53 "CCKBR,CD81,CDC42,RUBCN,EEF1A2,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,KIT,PDGFRA,PIK3R1,PTK2,AMBRA1,TEK,PIK3R5,VAV2" GO: Biological Process GO:0014032 neural crest cell development 7.42E-04 1.00E+00 1.28E-02 1.25E-01 26 76 "SEMA6A,SEMA7A,SEMA4G,NRP2,ZEB2,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,ERBB4,SEMA6C,SEMA4D,GBX2,KITLG,PAX6,SEMA5B,MAPK3,RET,SOX8,SEMA6D,SOX10,SOX11,SEMA4A,DICER1,SEMA3B" GO: Biological Process GO:0040012 regulation of locomotion 7.57E-04 1.00E+00 1.30E-02 1.27E-01 196 866 "ABR,ABHD6,ADORA1,ADORA2A,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,SEMA7A,APC,EPB41L5,SHTN1,SEMA4G,ARHGAP5,ARHGDIA,CHRD,NUMB,ADAM15,BBS2,NRP2,ARHGEF7,C5,IL33,LDLRAD4,CAMK2D,SPAG9,LDB2,KRIT1,RGN,SCARB1,CD81,NOG,ADGRG1,CHRM1,CHRM4,SLIT2,BAG4,NRG2,HS3ST5,CSF1,CSF1R,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,HDAC4,DAPK3,DBN1,MAGI2,SRGAP3,DRD1,DSCAM,WDPCP,EDN1,EDN3,EDNRA,SEMA3D,EGFR,PLXNC1,DMTN,ERBB2,ERBB4,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FER,FGF1,OLFM1,FGFR1,FGR,SEMA6C,EVL,SEMA4D,FLT1,TBR1,NRG3,GAB1,GCNT2,PPARGC1A,GPER1,RAPGEF4,RFFL,GRM5,GSN,BVES,ATOH8,HAS2,PADI2,NCKAP1L,HMGB1,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INSM1,ITGAV,JAK2,KIT,LAMA2,PAXBP1,KITLG,NBL1,NF1,NFE2L2,NODAL,NTRK3,DDR2,PAK3,PAX6,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,PIK3CD,PIK3R1,PLXNB1,PLXNB3,EPB41L4B,PKN2,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRO,PTPRZ1,PTX3,FEZF2,RDX,RET,ROBO1,ROBO2,FBXW7,PRR5L,LRRK2,AP1AR,SEMA6D,SELL,SGK1,DOCK10,FUZ,ST6GAL1,SLC8A1,SLIT1,SMARCA4,SNCA,PBLD,CLASP2,SST,KANK1,SYNE2,PLCB1,TAC1,TACR1,SEMA4A,EXOC7,UNC5D,CLASP1,TEK,TF,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,P2RY12,WNT7A,NDRG4,SCG2,SEMA3B,RTN4,SPATA13" GO: Biological Process GO:0014887 cardiac muscle adaptation 7.65E-04 1.00E+00 1.31E-02 1.28E-01 11 22 "ATP2A2,HDAC4,OGA,MEF2C,MYH6,MYH7,NPPA,PPP3CA,CAMTA2,HEY2,TRPC3" GO: Biological Process GO:0097104 postsynaptic membrane assembly 7.70E-04 1.00E+00 1.31E-02 1.28E-01 6 8 "CDH2,NRXN1,NRXN2,MAGI2,NLGN3,NLGN1" GO: Biological Process GO:1901897 regulation of relaxation of cardiac muscle 7.70E-04 1.00E+00 1.31E-02 1.28E-01 6 8 "CAMK2D,CAMK2G,CHGA,AKAP6,PDE4B,PDE4D" GO: Biological Process GO:0019637 organophosphate metabolic process 7.77E-04 1.00E+00 1.32E-02 1.29E-01 256 1164 "ACHE,ABHD6,SLC25A25,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,SLC44A5,NME5,AK2,PLA2G6,ADGRF5,AMPD2,AMPD3,OGT,KCNAB2,APLP1,UPRT,GPAM,NT5C3B,APOC1,APOC2,PDXK,CASK,PLA2G4C,PDE8B,ATM,ATP1A2,ATP2B2,ATP6V0A1,FGF17,LDHD,SYNJ1,SYNJ2,MTMR3,MTMR2,CACNB4,CALM1,NFS1,CBS,CCKBR,MTMR7,CD86,SCARB1,ENTPD2,CD81,CDC42,CHGA,CPNE6,PLAA,TJP2,SULT4A1,PCYT1B,AKAP6,AKAP5,TBPL1,COX4I1,NRG2,CPS1,ENTPD4,AKAP12,NCOR1,GDA,CSF1R,PLCH2,PITPNM3,PNPLA8,RUBCN,HDAC4,IP6K1,DBI,PLPPR4,AK5,DLG2,DLG3,DLG4,DRD1,DNM1L,EDN1,EDNRA,EDNRB,SH3GLB1,EGFR,CALCRL,ENO2,COQ7,ENPP6,GPHN,ERBB2,ERBB4,GMPR2,SH3YL1,PTK2B,RACK1,FDFT1,FGF1,FGFR1,FGFR3,FGR,PRKAG2,ATP5PD,CAP2,IP6K2,FLT1,AK8,TPK1,OGA,FYN,GAB1,GABBR1,HRASLS5,GALR1,IP6K3,INPP5K,GART,GCK,SULT1C4,PPARGC1A,RUNDC3A,GK,GNAL,GNAS,GPD1,GPD2,GPER1,PLCD4,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,TNFAIP8L3,ACOT7,HMGCR,HPCA,HTR2A,IDH3A,IDH3B,IGF1,INPP1,INPP5B,NME9,ITPKA,ITPKB,KHK,KIT,KITLG,MPP2,MYH3,MYH6,MYH7,P2RY13,NCF2,NDUFA5,NF1,NME4,NOS1,NPPA,NPR2,NUCB2,OCRL,OGDH,OGG1,OPRL1,P2RX7,P2RY1,PALM,PC,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PDGFRA,ENPP2,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,PGAM2,PIK3C2A,PIK3CD,PIK3R1,PKM,PLCB2,PLCD1,SLC25A23,ASPDH,MBOAT7,PPARA,CRLS1,MAPK7,FITM2,PRPSAP2,NDUFS7,PIGG,PTAFR,PLPPR1,PTHLH,PTH1R,PTK2,PID1,NUDT11,MRAP2,RPE,ADAL,LRRK2,PLPPR3,SCP2,SMPD3,HKDC1,MAGI3,AMBRA1,NAXD,OGDHL,SNCA,NMNAT2,LHPP,NUDT10,PLCB1,SLC37A2,DDHD2,ACSL6,TEK,GPR161,SLC44A1,MTMR14,TK2,DDHD1,PIK3R5,SMUG1,NEIL2,PLPPR2,VAV1,VAV2,VIPR2,ETNPPL,PLPP4,SPHK2,PLPPR5,SMARCAD1,PRTFDC1,NT5M,MPPE1,PLD4" GO: Biological Process GO:0048172 regulation of short-term neuronal synaptic plasticity 7.82E-04 1.00E+00 1.32E-02 1.29E-01 9 16 "PPFIA3,SHISA7,GRIK1,GRIK2,SHISA6,RAB3A,SLC8A2,RAB3GAP1,SYP" GO: Biological Process GO:1900273 positive regulation of long-term synaptic potentiation 7.82E-04 1.00E+00 1.32E-02 1.29E-01 9 16 "DRD1,NPTN,PTPN5,HNRNPK,NOS1,NRGN,RELN,STAU1,CRTC1" GO: Biological Process GO:0001956 positive regulation of neurotransmitter secretion 7.82E-04 1.00E+00 1.32E-02 1.29E-01 9 16 "ADORA2A,CACNA1B,GPER1,STX1B,NLGN1,RAB3GAP1,RIMS1,SNCA,STX1A" GO: Biological Process GO:0032230 "positive regulation of synaptic transmission, GABAergic" 7.82E-04 1.00E+00 1.32E-02 1.29E-01 9 16 "ADORA2A,HAP1,CCKBR,ERBB4,GRIK1,OXTR,NLGN1,TAC1,TACR1" GO: Biological Process GO:0009719 response to endogenous stimulus 8.00E-04 1.00E+00 1.35E-02 1.32E-01 370 1740 "SERPINA3,ABAT,ACTN2,ARID1A,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,NR0B1,OSBPL8,AK2,ALAD,LTBP4,OGT,APAF1,APC,EPB41L5,APLP1,UPRT,GPAM,APP,ARNTL,ARRB2,ASCL1,ASPH,CHRD,NCOA1,RASL11B,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP6V1G2,ATP6V0A1,BBS2,BCHE,RGS9,HCN2,FGF17,BID,BLM,BMP7,BMPR1B,LDLRAD4,CACNA1B,CALM1,KALRN,CAMK2A,CBS,P2RX6,AIFM1,CD38,NEURL1,CD81,ARHGEF2,CDO1,NOG,CHRNA4,CHRNB2,SLIT2,SLC22A6,ZFYVE9,ABCG2,CNGA3,CNR1,AKAP7,AKAP6,AKAP5,BAG4,CPS1,CLOCK,CREM,CRHBP,CRY2,RNF14,NCOR1,ABCG1,APPL1,CX3CR1,HDAC9,HDAC4,ZFYVE16,MED24,MAGI2,LYPD1,PARD6A,ARNT2,CHRDL1,DLG4,MED12,NR1D2,DNM2,CPEB2,DPYSL2,DRD1,EDN1,EDNRA,HEYL,EGFR,EGR3,DMTN,EPHA5,RRAGB,ECSIT,F3,PTK2B,PPP1R1B,FECH,FER,FGF1,FGF12,FGF14,FGFR1,FGFR3,BAIAP2,FOXM1,FOLR2,SORBS1,UFM1,TRIM16,NPTN,ATP6V1H,FYN,DKK3,GAB1,GABBR1,GABRA1,GABRB1,GABRB3,GABRG2,AHCYL1,INPP5K,GATM,GCK,GCNT2,GDF1,MSTN,GDF9,SESN1,GHR,PPARGC1A,GLRB,GNAL,GNAO1,GNAS,GNG3,GNG4,FERMT2,GPD1,GPR22,GPER1,STMN2,GRB10,RAPGEF1,GRIN1,NR3C1,GSN,RNF165,PTPN5,IRAK3,HAS2,TOX2,PADI2,HMGB1,HNF4G,HNMT,HNRNPK,HPCA,HSP90AA1,HTR2A,HTR5A,IGF1,IGFBP1,RBPJ,HES5,JAK2,KCNC1,KCNC2,KCND3,KCNJ11,KCNK1,KCNMA1,KHK,KIT,IPO5,LIMS1,LMO2,FGFBP3,SMAD1,SMAD9,MAOB,MAT2A,MBD1,MBP,MEF2C,MOG,SESN3,MSI1,MT3,MYH6,MYO5A,HNRNPM,NASP,NBL1,NCAM1,NCF2,SFR1,NEFH,NKX2-2,NODAL,VWA2,NOS1,NPPA,HCN1,NTRK2,NTRK3,NUCB2,OGG1,OPRL1,OXTR,P2RX7,TREM2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDE1B,PDGFRA,PDPK1,GPR173,GNG2,PENK,SSH1,PIK3C2A,PIK3R1,PKM,PLCD1,STRN3,POLR2F,PPARA,MED1,PPP3CA,PPP5C,PRKACB,SKOR1,PRKAR1B,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK7,MAPK9,BCAS3,PTAFR,PTCH1,PTK2,PTN,PTPRE,CASTOR1,PTPRN,PYGM,QDPR,PID1,FAT4,RAP1GAP,RBBP8,RDX,DUSP15,TRIM68,RNASEL,ROBO2,RORB,RPE65,TMEM100,LRRK2,PAQR6,RXRA,RXRG,RYR1,RYR3,S100B,SAFB,SOX6,SELL,SGK1,KIF16B,CPEB3,FUZ,SLC1A2,SLC1A3,SLC6A1,SLC8A1,SLC8A3,SIRT2,CPEB4,SMARCA4,SNCA,MBD5,LMBRD1,SNRPN,WDTC1,SOX5,SOX11,KDM3A,SPP1,PEG10,ZNF423,SPART,LMO3,PBLD,SST,SSTR1,SSTR2,ERBIN,KANK1,SULF2,ACSBG1,ABCC8,PLCB1,TAC1,MMS19,TACR1,ADGRL3,TBL1X,VWC2,TCF7L2,ZEB1,TEK,SIRT1,LEFTY2,TGFBR3,ZNF106,HHIP,THRA,TIAM1,HEY1,TIMP4,NR2E1,PARD3,RBFOX2,WBP2,RGMB,NR2C2,TRH,STXBP4,TRPC3,TSC1,TSC2,TUB,UBC,UBE3A,FLRT2,FLRT1,VGF,VLDLR,P2RY12,WNT7A,ATP6V0E2,CRB2,PMEPA1,PRDM2,RGMA" GO: Biological Process GO:0061061 muscle structure development 8.04E-04 1.00E+00 1.35E-02 1.32E-01 153 657 "ACADM,ACHE,ACTN2,ARID1A,ADRB2,AGT,MRTFA,BIN1,ANK2,PI16,ARNTL,ATP2A2,ADGRB3,CFLAR,SGCE,FOXK1,CACNB4,CAMK2D,CAPN3,CAST,SPAG9,USP2,NEURL1,CDC42,CDH2,LARGE1,NOG,CACNA2D2,CFL2,MYL6B,QKI,CNTFR,AKAP6,HINFP,NCOR1,CSF1R,CMTM5,CTH,BOC,HDAC9,RIPOR2,HDAC4,MAML1,MYEF2,DMD,DMPK,NR1D2,CDON,RCAN1,EDN1,EDNRB,HEYL,KMT5B,EGR3,SRPK3,PLEKHO1,ERBB4,SPEG,ETV1,FKTN,FGFR1,FHL1,FLNC,PDLIM5,MEGF10,DNER,MSTN,USP19,GPER1,PLPP7,NR3C1,RNF165,BVES,HLF,HMGCR,EID2B,MYLK2,IGF1,NKD1,RBPJ,ITGA7,KCNH1,KCNK2,KIT,LAMA2,PAXBP1,MBNL1,MEF2C,MYH3,MYH6,MYH7,MYL3,MYT1,NACA,NCAM1,NF1,NOS1,NPPA,PDGFRA,TMOD2,PIK3R1,TNPO2,POU6F1,MED1,PPP3CA,PROX1,PSMA6,PBRM1,MYH14,SOX8,RXRA,RYR1,S100B,MAPK12,SCN8A,SOX6,MRAS,FHOD3,SMTN,SLC8A1,SIRT2,EPC1,SMARCA4,SMARCD3,MYH15,SOX11,SOX15,MESP1,PLCB1,SIN3B,TCF7L2,ZEB1,TCF12,SYNE1,OBSL1,DICER1,SIRT1,ZFPM2,TGFBR3,THRA,HEY1,TLL2,HEY2,TMOD1,TPM1,NR2C2,TSC1,HIRA,UCHL1,KCNAB1,VANGL2,FXR1,IFT88" GO: Biological Process GO:0051057 positive regulation of small GTPase mediated signal transduction 8.05E-04 1.00E+00 1.35E-02 1.32E-01 18 46 "ALS2,ARRB1,MMD2,CAMK2D,DGKI,ADGRG1,CSF1,CDON,DOCK2,RASGRP1,ERBB2,IGF1,ITPKB,KITLG,RELN,RASGRF1,ROBO1,MCF2L" GO: Biological Process GO:0061572 actin filament bundle organization 8.14E-04 1.00E+00 1.37E-02 1.34E-01 41 138 "ACTN1,ADD1,ADD2,PPFIA1,GAS7,SHTN1,SHROOM2,ARRB1,CDC42,BAG4,ARHGEF10,DBN1,SHANK1,USH1C,SORBS3,DMTN,EPS8,PTK2B,DLC1,BAIAP2,EVL,SORBS1,INPP5K,SYNPO,DBNL,PIK3R1,RDX,PPP1R9A,PPM1E,ASAP3,CLASP2,TAC1,TACR1,CLASP1,TPM1,TSC1,TMEFF2,AMOT,FMN2,SPIRE1,PCDH15" GO: Biological Process GO:0071870 cellular response to catecholamine stimulus 8.28E-04 1.00E+00 1.39E-02 1.36E-01 14 32 "ADCY6,APLP1,APP,AKAP6,DNM2,DRD1,GNAS,NOS1,PDE4B,PDE4D,GNG2,LRRK2,SIRT2,SNCA" GO: Biological Process GO:0038127 ERBB signaling pathway 8.40E-04 1.00E+00 1.41E-02 1.37E-01 44 151 "ADORA1,AP2A1,AP2A2,AGT,DGKD,APP,ZFYVE28,ARHGEF7,HAP1,NEURL1,REPS2,CDC42,EPS15L1,CLTA,NRG2,SOCS5,RASSF2,EGFR,EPS8,ERBB2,ERBB4,PTK2B,EFEMP1,FER,GAB1,GPER1,HSP90AA1,RBPJ,MATK,SHC3,PDPK1,PIK3C2A,PIK3R1,EPN1,SH3KBP1,PTK2,SH3TC2,FBXW7,SH3GL2,KIF16B,ERBIN,UBC,MVB12B,SOCS4" GO: Biological Process GO:0051017 actin filament bundle assembly 8.46E-04 1.00E+00 1.41E-02 1.38E-01 40 134 "ACTN1,ADD1,ADD2,PPFIA1,GAS7,SHROOM2,ARRB1,CDC42,BAG4,ARHGEF10,DBN1,SHANK1,USH1C,SORBS3,DMTN,EPS8,PTK2B,DLC1,BAIAP2,EVL,SORBS1,INPP5K,SYNPO,DBNL,PIK3R1,RDX,PPP1R9A,PPM1E,ASAP3,CLASP2,TAC1,TACR1,CLASP1,TPM1,TSC1,TMEFF2,AMOT,FMN2,SPIRE1,PCDH15" GO: Biological Process GO:0043254 regulation of protein complex assembly 8.48E-04 1.00E+00 1.41E-02 1.38E-01 99 400 "ADD1,ADD2,APC,SPTBN4,BID,WASF1,LDLRAD4,CCK,CDC42,SLIT2,CLU,PICK1,BAG4,CHD1L,GDA,CLIP3,MYADM,DBN1,PDCD6IP,DNM1L,SH3GLB1,ABI2,TENM1,DMTN,EPS8,ERCC2,PTK2B,RACK1,SEC24B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,ARFIP1,GFAP,PSRC1,STMN2,TPPP,GSN,NCKAP1L,HMGB1,HSP90AA1,IRF8,SCIN,INSM1,STMN1,MAPT,MITF,DBNL,NCAM1,PAK3,TMOD2,MAGEL2,PRKCZ,MAPK8,MAPK9,PEX5,CEP97,RDX,KIRREL1,ATAT1,CLIP1,STX1B,AP1AR,FNIP1,SGK1,PPP1R9A,FHOD3,RAB3GAP1,SIRT2,NAPB,ATF7IP,RIMS1,SNCA,PALLD,SPTAN1,SPTB,CLASP2,STX1A,KANK1,STXBP1,MLST8,TAL1,CLASP1,THRA,TLR4,HEY2,TMOD1,WIPF1,RICTOR,TRIM9,FMN2,SPIRE1,TFIP11,PMEPA1,WIPF2,ACTR3B,SLC39A12" GO: Biological Process GO:0050974 detection of mechanical stimulus involved in sensory perception 8.48E-04 1.00E+00 1.41E-02 1.38E-01 16 39 "ASIC2,ATP2B2,ASIC3,ADGRV1,FYN,GRIN2D,GRM8,HTR2A,IGF1,KCNA1,KIT,SERPINE2,STRC,SLC12A2,SOX2,PCDH15" GO: Biological Process GO:0006887 exocytosis 8.76E-04 1.00E+00 1.46E-02 1.42E-01 107 438 "SERPINA3,ABR,ACTN1,ACTN2,ADORA3,PLA2G6,SYT13,DOC2A,ANK1,APP,CADPS,ATP2A2,SYNJ1,BTK,CACNA1I,CACNA1G,CDK5R2,CACNA1A,CALM1,HAP1,SYT6,BRSK2,CBARP,CHGA,RAB3C,NRXN1,CLU,RAB26,CRHBP,RIMS4,RIMS2,SNPH,RIMS3,SCRN1,BLOC1S6,PDCD6IP,SYT15,RASGRP1,DMTN,RABEPK,STX2,F5,F8,PRAM1,FER,FGR,VTI1B,SYT3,BRPF3,SYT17,CPLX2,CPLX1,PCLO,RAPGEF4,GRIK5,IL1RAPL1,IGF1,SCIN,C2CD4C,KCNB1,KIT,STXBP5,LAMP2,SYTL4,SYT9,SCAMP5,SCG3,MYO5A,NCAM1,P2RX7,PDPK1,PIK3C2A,PIK3CD,PPP3CB,SYTL2,PTAFR,RAB3A,LRRK2,STX1B,SMPD3,NLGN1,RPH3A,RAB3GAP1,NAPB,LGI3,RIMS1,SNAP25,SNCA,CLASP2,STX1A,STXBP1,SYT11,VAMP1,PLCB1,SYN1,SYT1,SYT4,SYT5,EXOC7,CLASP1,ATP13A2,TF,LEFTY2,VSNL1,LAT2,TRIM9,C12orf4" GO: Biological Process GO:0008347 glial cell migration 8.88E-04 1.00E+00 1.47E-02 1.44E-01 19 50 "CDK5R1,ARHGEF7,CDK5R2,ADGRG1,CSF1,VCAN,EFEMP1,FOXG1,DISC1,MATN2,P2RY1,MBOAT7,RELN,PTPRZ1,TIAM1,NR2E1,P2RY12,LRP8,RTN4" GO: Biological Process GO:0090276 regulation of peptide hormone secretion 8.92E-04 1.00E+00 1.48E-02 1.44E-01 63 235 "ABAT,ADCY5,PLA2G6,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,C2CD2L,SIDT2,EGFR,EPHA5,OGA,GABBR1,GCK,GLUL,GNAS,GPER1,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYT1,NEUROD1,NNAT,NOS1,NUCB2,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,RFX3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VSNL1" GO: Biological Process GO:0009132 nucleoside diphosphate metabolic process 9.09E-04 1.00E+00 1.50E-02 1.47E-01 38 126 "NME5,AK2,AMPD3,OGT,CASK,ENTPD2,TJP2,ENTPD4,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,ENO2,PRKAG2,AK8,GCK,PPARGC1A,GPD1,HTR2A,IGF1,NME9,KHK,MPP2,NME4,OGDH,P2RX7,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,PKM,PPARA,HKDC1,MAGI3,OGDHL" GO: Biological Process GO:0060048 cardiac muscle contraction 9.40E-04 1.00E+00 1.55E-02 1.52E-01 37 122 "ADORA1,ADRA1B,ANK2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP2A2,CACNA2D1,CACNB2,CALM1,CAMK2D,CHGA,AKAP6,NOS1AP,HDAC4,DMD,FGF12,GAA,HSP90AA1,MYLK2,KCNH2,CTNNA3,MYH6,MYH7,MYL3,NOS1,NPPA,PDE4B,PDE4D,FXYD1,SCN2B,SCN4B,SLC8A1,SCN3B,TPM1,KCNE5" GO: Biological Process GO:0002791 regulation of peptide secretion 9.46E-04 1.00E+00 1.56E-02 1.52E-01 64 240 "ABAT,ADCY5,ADORA1,PLA2G6,MADD,ARNTL,ARRB1,PDE8B,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,C2CD2L,SIDT2,EGFR,EPHA5,OGA,GABBR1,GCK,GLUL,GNAS,GPER1,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYT1,NEUROD1,NNAT,NOS1,NUCB2,PAX6,PDE1C,PDE3B,PFKFB2,PPP3CA,PPP3CB,RFX3,SYBU,SNAP25,STX1A,ABCC8,TCF7L2,SIRT1,TIAM1,TRH,STXBP4,TRPM2,VSNL1" GO: Biological Process GO:0010107 potassium ion import 9.58E-04 1.00E+00 1.57E-02 1.54E-01 13 29 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,SLC12A6,ABCC9,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16" GO: Biological Process GO:1902668 negative regulation of axon guidance 9.58E-04 1.00E+00 1.57E-02 1.54E-01 13 29 "SEMA6A,SEMA7A,SEMA4G,SLIT2,SEMA3D,SEMA6C,SEMA4D,SEMA5B,PTPRO,SEMA6D,SLIT1,SEMA4A,SEMA3B" GO: Biological Process GO:0010656 negative regulation of muscle cell apoptotic process 9.73E-04 1.00E+00 1.60E-02 1.56E-01 17 43 "ARRB2,BMP7,QKI,EDN1,ERBB4,PTK2B,HMGCR,IGF1,RBPJ,JAK2,LIFR,NACA,NFE2L2,PDPK1,PIK3R1,SIRT1,HEY2" GO: Biological Process GO:0030833 regulation of actin filament polymerization 1.02E-03 1.00E+00 1.67E-02 1.63E-01 43 148 "ADD1,ADD2,SPTBN4,WASF1,SLIT2,PICK1,BAG4,MYADM,DBN1,ABI2,TENM1,DMTN,EPS8,PTK2B,FER,BAIAP2,EVL,NCKAP1,IQGAP2,ARFIP1,GSN,NCKAP1L,SCIN,DBNL,PAK3,TMOD2,MAGEL2,RDX,KIRREL1,AP1AR,PPP1R9A,FHOD3,SPTAN1,SPTB,KANK1,MLST8,TMOD1,WIPF1,RICTOR,FMN2,SPIRE1,WIPF2,ACTR3B" GO: Biological Process GO:0001661 conditioned taste aversion 1.08E-03 1.00E+00 1.75E-02 1.71E-01 5 6 "CHRNB2,DRD1,TBR1,GRIN1,GRM7" GO: Biological Process GO:0038007 netrin-activated signaling pathway 1.08E-03 1.00E+00 1.75E-02 1.71E-01 5 6 "UNC5A,SHTN1,DCC,PTK2,UNC5B" GO: Biological Process GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 1.08E-03 1.00E+00 1.75E-02 1.71E-01 5 6 "CACNB2,CAMK2D,NOS1AP,NOS1,NPPA" GO: Biological Process GO:0042596 fear response 1.08E-03 1.00E+00 1.75E-02 1.71E-01 18 47 "ALS2,PDE8B,CACNA1E,KALRN,CCK,BRINP1,DBI,LYPD1,DRD1,EIF4G1,GABRA5,GRIK2,GRM7,MEF2C,NEUROD2,PENK,ANKFN1,NR2E1" GO: Biological Process GO:0021762 substantia nigra development 1.08E-03 1.00E+00 1.75E-02 1.71E-01 18 47 "NDRG2,DYNLL1,CALM1,INA,SYNGR3,CDC42,SEC16A,FGFR3,TTBK1,PADI2,MAG,MAOB,MBP,PLP1,MAPKAP1,ZNF430,SIRT2,CCDC14" GO: Biological Process GO:0014888 striated muscle adaptation 1.08E-03 1.00E+00 1.75E-02 1.71E-01 18 47 "ATP2A2,CFLAR,CAMK2B,CAMK2G,HDAC4,OGA,MSTN,PPARGC1A,GSN,MEF2C,MYH6,MYH7,NPPA,PPP3CA,CAMTA2,HEY2,TNNT1,TRPC3" GO: Biological Process GO:0071709 membrane assembly 1.09E-03 1.00E+00 1.76E-02 1.72E-01 12 26 "NLGN4X,ANK3,CDH2,NRXN1,NRXN2,MAGI2,STX2,IL1RAPL1,PACSIN2,NLGN3,PTPRD,NLGN1" GO: Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway 1.09E-03 1.00E+00 1.76E-02 1.72E-01 12 26 "CACNA1A,CACNB4,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,PLCL1" GO: Biological Process GO:0045822 negative regulation of heart contraction 1.09E-03 1.00E+00 1.76E-02 1.72E-01 12 26 "ADORA1,ADRA1D,SPTBN4,ATP1A1,ATP1A2,ATP2A2,JAK2,NOS1,PDE4D,PIK3R1,TAC1,SPX" GO: Biological Process GO:0007423 sensory organ development 1.11E-03 1.00E+00 1.79E-02 1.75E-01 139 594 "ABR,ACHE,ARID1A,SLC25A25,CC2D2A,BCAR3,APC,LGR5,SHROOM2,ASCL1,ATP2B1,ATP2B2,PROM1,BMP7,BMPR1B,DDR1,CALB1,NOG,LHX2,KMT2C,VAX2,NIPBL,CNGA3,WHRN,SLC4A7,NECTIN3,LRIG1,ZEB2,GSDME,PLPPR4,CHRDL1,CDON,DSCAM,USH1C,WDPCP,EDN1,EGFR,ABI2,EPHB1,ADGRV1,EYA1,EFEMP1,SEC24B,FGFR1,FGFR3,FOXG1,FOXF2,FLT1,STAU2,MEGF11,GABRA5,GABRB3,ATP8A2,GBX2,GLI2,KDM2B,GPD2,GPM6A,CECR2,KIF3A,HMGB1,HNRNPK,HPCA,IFI16,IGF1,NKD1,RBPJ,HES5,OLFM3,KCNK2,KCNK3,KCNMA1,MEIS1,MEIS2,MITF,MYCN,MYO6,MYO7A,NDP,NEUROD1,NF1,HCN1,NTRK2,NTRK3,PAX6,PDGFRA,CYTL1,TMIE,PRRX1,SDK2,FAT3,POU3F4,MED1,MAPK3,PROX1,LAMA1,PTN,STRC,TMEM231,FAT4,RET,ROM1,RORB,RPE65,RPL38,SOX8,RXRA,SALL1,RAB3GAP1,SMARCA4,SMARCD3,MYH15,IFT122,SOX1,SOX2,SOX3,SOX11,STOX1,SMOC1,JMJD6,AGTPBP1,ZEB1,RPGRIP1L,DICER1,CRB1,HEY1,NR2E1,HEY2,TMOD1,TUB,WNT7A,ZIC1,CRB2,CELF4,PCDH15,SLC17A7,FZD3,VANGL2,IFT88" GO: Biological Process GO:0010563 negative regulation of phosphorus metabolic process 1.13E-03 1.00E+00 1.81E-02 1.77E-01 140 599 "NDRG2,ADAR,ELFN2,ADORA2A,OGT,APC,APLP1,APOC1,LRRC4C,SLC7A14,PPP4R4,ZFYVE28,ARRB1,DYNLL1,BMP7,LDLRAD4,CALM1,RGN,NOG,SOCS6,SLIT2,FBXO7,AKAP6,AKAP5,BAG4,CRY2,NCOR1,SOCS5,PPP1R16B,RUBCN,MYADM,HDAC4,RASSF2,PARD6A,DLG2,DLG3,DMD,DRD1,DUSP9,EDN1,EDNRA,EDNRB,HIPK3,DMTN,TAOK3,RACK1,FKTN,PPP1R1B,PRKAG2,RGPD5,FOXM1,SEMA4D,ZBED3,GABBR1,ZMYND11,GALR1,INPP5K,MSTN,GFRA2,PPARGC1A,PCDH11X,GPER1,GRB10,RAPGEF1,C1QL4,GRM2,GRM3,GRM7,GRM8,PTPN5,IRAK3,HRH3,NCKAP1L,HMGCR,HPCA,IGF1,INSM1,LRRTM3,LRRTM1,LRRC4B,CAMK2N2,P2RY13,NELL1,NF1,NOS1,NTRK3,NUCB2,OPRL1,P2RX7,PALM,PAX6,PDE2A,PDE4D,PDPK1,DUSP26,PPARA,PPP1R1A,PTPA,PPP5C,PKIA,PRKAR1B,PRKCZ,MAPK7,SYTL2,PID1,RGS3,RGS4,KIRREL1,PRR5L,LRRK2,CSRNP3,ATXN1,ATXN7,LRRTM4,PPM1E,SIRT2,CDK5RAP3,TMEM132D,SNCA,DBNDD2,RBM26,LMO3,PBLD,SAMSN1,LRRC4,MPRIP,SIRT1,TLR4,RIMBP2,PARD3,TSC2,UCHL1,FLRT2,FLRT1,MICAL1,ELFN1,WNK1,PMEPA1,WNK2,SOCS4" GO: Biological Process GO:0045936 negative regulation of phosphate metabolic process 1.13E-03 1.00E+00 1.81E-02 1.77E-01 140 599 "NDRG2,ADAR,ELFN2,ADORA2A,OGT,APC,APLP1,APOC1,LRRC4C,SLC7A14,PPP4R4,ZFYVE28,ARRB1,DYNLL1,BMP7,LDLRAD4,CALM1,RGN,NOG,SOCS6,SLIT2,FBXO7,AKAP6,AKAP5,BAG4,CRY2,NCOR1,SOCS5,PPP1R16B,RUBCN,MYADM,HDAC4,RASSF2,PARD6A,DLG2,DLG3,DMD,DRD1,DUSP9,EDN1,EDNRA,EDNRB,HIPK3,DMTN,TAOK3,RACK1,FKTN,PPP1R1B,PRKAG2,RGPD5,FOXM1,SEMA4D,ZBED3,GABBR1,ZMYND11,GALR1,INPP5K,MSTN,GFRA2,PPARGC1A,PCDH11X,GPER1,GRB10,RAPGEF1,C1QL4,GRM2,GRM3,GRM7,GRM8,PTPN5,IRAK3,HRH3,NCKAP1L,HMGCR,HPCA,IGF1,INSM1,LRRTM3,LRRTM1,LRRC4B,CAMK2N2,P2RY13,NELL1,NF1,NOS1,NTRK3,NUCB2,OPRL1,P2RX7,PALM,PAX6,PDE2A,PDE4D,PDPK1,DUSP26,PPARA,PPP1R1A,PTPA,PPP5C,PKIA,PRKAR1B,PRKCZ,MAPK7,SYTL2,PID1,RGS3,RGS4,KIRREL1,PRR5L,LRRK2,CSRNP3,ATXN1,ATXN7,LRRTM4,PPM1E,SIRT2,CDK5RAP3,TMEM132D,SNCA,DBNDD2,RBM26,LMO3,PBLD,SAMSN1,LRRC4,MPRIP,SIRT1,TLR4,RIMBP2,PARD3,TSC2,UCHL1,FLRT2,FLRT1,MICAL1,ELFN1,WNK1,PMEPA1,WNK2,SOCS4" GO: Biological Process GO:0018209 peptidyl-serine modification 1.14E-03 1.00E+00 1.83E-02 1.78E-01 72 278 "CDC7,AGT,BCAR3,OGT,SPTBN4,ARRB1,ARRB2,CAPRIN2,ATM,RIPK1,CDK5R1,CAMK2A,CAMK2B,CAMK2D,BRSK2,CDC42,DCLK1,BAG4,CSNK1E,CSNK1G3,RASSF2,SPOCK2,SPOCK3,DMD,DMPK,DYRK1A,SGK2,HIPK3,TENM1,DMTN,RACK1,MAD2L2,BRSK1,CAB39,NEK6,INPP5K,GFRA2,TTBK1,DCLK2,DOCK7,STK32C,NOS1,NTRK2,NTRK3,PDE4D,PDPK1,PKD1,PLCL1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK7,MAPK8,STK32A,RET,RPS6KA2,STK32B,LRRK2,MAPK12,FNIP1,SGK1,MAST1,SNCA,STOX1,TTBK2,NSD1,TEK,SGK3,RICTOR,MAP3K12" GO: Biological Process GO:1901019 regulation of calcium ion transmembrane transporter activity 1.14E-03 1.00E+00 1.83E-02 1.78E-01 25 74 "PLA2G6,ANK2,ASPH,ATP1A2,CACNA2D1,CACNB2,CACNB4,CALM1,HAP1,CAMK2D,RGN,CBARP,AKAP6,NOS1AP,DMD,FGF14,JPH4,MYO5A,NOS1,NPPA,OPRL1,PDE4B,PDE4D,SLN,JPH3" GO: Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 1.14E-03 1.00E+00 1.83E-02 1.78E-01 25 74 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,APLP1,GPR37L1,CHRM1,CHRM4,PRMT5,GABBR1,GNAL,MCHR1,GPR37,GRIK3,GRM2,GRM3,GRM7,GRM8,PTGDR2,HRH3,OPRL1,P2RY1,SSTR2,P2RY12" GO: Biological Process GO:0014049 positive regulation of glutamate secretion 1.17E-03 1.00E+00 1.85E-02 1.81E-01 7 11 "ADORA2A,CCK,DPYSL2,GABBR1,NR3C1,P2RX7,RAB3GAP1" GO: Biological Process GO:1901077 regulation of relaxation of muscle 1.17E-03 1.00E+00 1.85E-02 1.81E-01 7 11 "CAMK2D,CAMK2G,CHGA,AKAP6,PDE4B,PDE4D,SLN" GO: Biological Process GO:0021891 olfactory bulb interneuron development 1.17E-03 1.00E+00 1.85E-02 1.81E-01 7 11 "SLIT2,FGFR1,SALL3,ROBO1,ROBO2,ARX,SLIT1" GO: Biological Process GO:0072578 neurotransmitter-gated ion channel clustering 1.17E-03 1.00E+00 1.85E-02 1.81E-01 7 11 "NRXN1,DLG4,GPHN,GLRB,RELN,LRRTM4,NLGN1" GO: Biological Process GO:0090129 positive regulation of synapse maturation 1.17E-03 1.00E+00 1.85E-02 1.81E-01 7 11 "CAMK2B,NEURL1,NRXN3,NRXN1,HNRNPK,NEUROD2,RELN" GO: Biological Process GO:0030049 muscle filament sliding 1.17E-03 1.00E+00 1.85E-02 1.81E-01 16 40 "ACTN2,MYL6B,DBN1,DMD,MYLK2,MYBPC1,MYH3,MYH6,MYH7,MYL3,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4" GO: Biological Process GO:0046579 positive regulation of Ras protein signal transduction 1.17E-03 1.00E+00 1.85E-02 1.81E-01 16 40 "ALS2,ARRB1,MMD2,CAMK2D,DGKI,ADGRG1,CSF1,DOCK2,RASGRP1,ERBB2,IGF1,ITPKB,KITLG,RASGRF1,ROBO1,MCF2L" GO: Biological Process GO:0031032 actomyosin structure organization 1.18E-03 1.00E+00 1.87E-02 1.82E-01 46 162 "ACTN2,CDC42BPA,PPFIA1,EPB41L5,ARRB1,CFLAR,LURAP1,CAPN3,CFL2,CNN3,BAG4,CDC42BPB,ARHGEF10,EDN1,SORBS3,PTK2B,DLC1,EVL,SORBS1,INPP5K,SYNPO,MEF2C,MYH3,MYH6,PDGFRA,TMOD2,PIK3R1,EPB41L4B,PROX1,MYH14,PPP1R9A,PPM1E,ASAP3,MYO18A,FHOD3,LIMCH1,CLASP2,TAC1,TACR1,CLASP1,OBSL1,TMOD1,TPM1,TSC1,TMEFF2,AMOT" GO: Biological Process GO:0071868 cellular response to monoamine stimulus 1.20E-03 1.00E+00 1.88E-02 1.83E-01 14 33 "ADCY6,APLP1,APP,AKAP6,DNM2,DRD1,GNAS,NOS1,PDE4B,PDE4D,GNG2,LRRK2,SIRT2,SNCA" GO: Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.20E-03 1.00E+00 1.88E-02 1.83E-01 14 33 "CDC42,SH3GLB1,ERBB4,PTK2B,FGFR3,FGR,FLT1,TNFAIP8L3,KIT,PDGFRA,PTK2,AMBRA1,TEK,VAV2" GO: Biological Process GO:0031113 regulation of microtubule polymerization 1.20E-03 1.00E+00 1.88E-02 1.83E-01 14 33 "APC,GDA,CLIP3,PSRC1,STMN2,STMN1,MAPT,MAPK8,CLIP1,SGK1,SNCA,CLASP2,CLASP1,SLC39A12" GO: Biological Process GO:0032958 inositol phosphate biosynthetic process 1.22E-03 1.00E+00 1.92E-02 1.87E-01 11 23 "ADCYAP1R1,IP6K1,PTK2B,IP6K3,GPER1,P2RY1,PLCD1,PTAFR,PTH1R,SCP2,SNCA" GO: Biological Process GO:0030032 lamellipodium assembly 1.31E-03 1.00E+00 2.05E-02 2.00E-01 21 59 "ARHGEF7,SLIT2,ARHGEF6,SH2B1,ARHGEF4,HDAC4,DNM2,DMTN,FER,NCKAP1,WASF3,HSP90AA1,KIT,SSH1,PLXNB3,PTPRO,ABLIM3,CCDC88A,FGD4,VAV2,SPATA13" GO: Biological Process GO:1903861 positive regulation of dendrite extension 1.33E-03 1.00E+00 2.08E-02 2.03E-01 10 20 "CPNE5,CPNE6,RIMS2,SYT3,SYT17,HNRNPK,CPNE9,RIMS1,SYT1,SYT4" GO: Biological Process GO:1903859 regulation of dendrite extension 1.33E-03 1.00E+00 2.08E-02 2.03E-01 10 20 "CPNE5,CPNE6,RIMS2,SYT3,SYT17,HNRNPK,CPNE9,RIMS1,SYT1,SYT4" GO: Biological Process GO:0098609 cell-cell adhesion 1.34E-03 1.00E+00 2.09E-02 2.04E-01 217 980 "TTYH1,ABAT,ACTN1,DSCAML1,ADORA2A,ADRB2,NLGN4X,PCDH19,C1QTNF1,ALCAM,PCDH10,ANK3,PKP4,APC,EPB41L5,GPAM,PCDHGB4,ASTN1,CADM3,BLM,BMP7,CDK5R1,CACNB4,CBLN1,CLDN10,CD86,CDC42,CDH2,CDH8,CDH10,CDH18,SOCS6,JAM2,SLIT2,NRXN3,NRXN1,NRXN2,NECTIN3,NCOR1,SOCS5,CTNND1,CTNND2,BOC,MYADM,CDON,DOCK2,DSCAM,DNAJB6,RASGRP1,EFNB3,CELSR3,EBI3,EGFR,EGR3,CERCAM,DMTN,ERBB2,CDHR1,ADGRV1,FCGR3A,FER,MAD2L2,MEX3B,SEMA4D,NPTN,ATP2C1,FYN,MEGF11,MEGF10,CHL1,IGSF5,GCNT2,PCDH17,MALT1,KIRREL3,GLI2,PCDH11X,GNAS,RAPGEF1,PTPRT,GSN,IL1RAPL1,BVES,HAS2,NCKAP1L,VSIG4,HMGB1,NEGR1,HSP90AA1,IGF1,IL6ST,IL12A,ITGA7,ITGAM,ITGAV,ITPKB,JAK2,CDH20,KIFC3,KIT,L1CAM,LIG4,LIMS1,LMO1,CD200,CCDC80,CTNNA3,NCAM1,NCAM2,NINJ2,NODAL,NRCAM,OLR1,CLDN11,P2RX7,PAK3,PCDHGC3,PCDH8,PCDH9,PDGFRA,PDPK1,NLGN3,SERPINE2,PIK3CD,PIK3R1,PKD1,PCDH18,MAPKAP1,RC3H2,SDK2,FAT3,PPARA,PPP3CA,PPP3CB,CEP41,PRKCZ,MAPK7,DCHS2,PTAFR,PTK2,PTPRD,PTPRG,FAT4,RAP1GAP,RDX,RET,ROBO1,KIRREL1,ROBO2,GLDN,SATB1,NLGN4Y,FNDC3A,NLGN1,CLSTN1,LIMS2,SLC11A1,ELMO2,IGSF9B,SOX2,NFASC,CLSTN2,STXBP1,JMJD6,SEMA4A,MLST8,UNC5D,ADGRL3,TCF7,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,DICER1,THBS4,CDH22,ICAM5,PARD3,TNR,TRO,TSC1,CADM1,VAV1,P2RY12,RICTOR,XRCC4,PCDH20,ZBTB16,CADM2,PCDH15,DOCK8,NLRP3" GO: Biological Process GO:0090128 regulation of synapse maturation 1.36E-03 1.00E+00 2.10E-02 2.05E-01 8 14 "CAMK2B,NEURL1,NRXN3,NRXN1,DISC1,HNRNPK,NEUROD2,RELN" GO: Biological Process GO:0035020 regulation of Rac protein signal transduction 1.36E-03 1.00E+00 2.10E-02 2.05E-01 8 14 "OGT,ALS2,CAMK2D,ARHGAP24,DNM2,DOCK2,NF1,RASGRF1" GO: Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway 1.36E-03 1.00E+00 2.10E-02 2.05E-01 8 14 "HOMER3,GRIK3,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" GO: Biological Process GO:0040034 "regulation of development, heterochronic" 1.36E-03 1.00E+00 2.10E-02 2.05E-01 8 14 "ASCL1,RBPJ,NODAL,PAX6,SERPINE2,SOX5,NR2E1,GDPD5" GO: Biological Process GO:0007605 sensory perception of sound 1.36E-03 1.00E+00 2.10E-02 2.05E-01 46 163 "ASIC2,AQP4,SPTBN4,ATP2B2,ALDH7A1,CACNA1D,CHRNB2,NIPBL,WHRN,COL11A2,CRYM,LRIG1,RIPOR2,GSDME,FAM107B,DNM1,USH1C,ADGRV1,EYA1,FGFR1,GABRA5,GABRB3,SRRM4,GRM7,KCNMA1,KIT,MBP,MYO6,MYO7A,NDP,OTOGL,TMIE,POU3F4,STRC,MYH14,RPL38,SCN8A,FBXO11,SLC1A3,SLC12A2,SOX2,TBL1X,TJP1,TUB,PCDH15,NAV2" GO: Biological Process GO:0016082 synaptic vesicle priming 1.39E-03 1.00E+00 2.14E-02 2.09E-01 9 17 "CADPS,SYNJ1,STX1B,RAB3GAP1,NAPB,RIMS1,SNAP25,STX1A,STXBP1" GO: Biological Process GO:0021542 dentate gyrus development 1.39E-03 1.00E+00 2.14E-02 2.09E-01 9 17 "DRD1,EMX2,KIF3A,NEUROD1,PROX1,RELN,FEZF2,ATAT1,NR2E1" GO: Biological Process GO:0060081 membrane hyperpolarization 1.39E-03 1.00E+00 2.14E-02 2.09E-01 9 17 "AGT,ATP1A1,CACNG2,KCNJ10,KCNQ2,KCNQ3,HCN1,PRKCZ,CRTC1" GO: Biological Process GO:0043583 ear development 1.41E-03 1.00E+00 2.16E-02 2.11E-01 63 239 "ABR,LGR5,SHROOM2,ATP2B2,DDR1,NOG,NIPBL,WHRN,SLC4A7,LRIG1,GSDME,PLPPR4,USH1C,WDPCP,EDN1,ADGRV1,EYA1,SEC24B,FGFR1,FGFR3,FOXG1,GABRA5,GABRB3,ATP8A2,GBX2,GLI2,CECR2,KIF3A,HPCA,IFI16,IGF1,RBPJ,HES5,KCNK2,KCNK3,KCNMA1,MYCN,MYO6,MYO7A,NEUROD1,NTRK3,CYTL1,TMIE,PRRX1,POU3F4,MAPK3,PROX1,STRC,FAT4,RPL38,SALL1,SOX2,STOX1,ZEB1,RPGRIP1L,DICER1,HEY1,HEY2,ZIC1,PCDH15,FZD3,VANGL2,IFT88" GO: Biological Process GO:0086009 membrane repolarization 1.41E-03 1.00E+00 2.17E-02 2.12E-01 15 37 "ANK2,ATP1A1,ATP1A2,ATP1B3,CACNA1D,CACNA2D1,AKAP7,AKAP6,NOS1AP,KCND3,KCNH2,NPPA,KCNIP2,SCN4B,KCNE5" GO: Biological Process GO:0002175 protein localization to paranode region of axon 1.48E-03 1.00E+00 2.25E-02 2.20E-01 4 4 "CNTNAP1,NFASC,EPB41L3,UGT8" GO: Biological Process GO:0046959 habituation 1.48E-03 1.00E+00 2.25E-02 2.20E-01 4 4 "DGKI,SHANK1,DRD1,EPM2A" GO: Biological Process GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly 1.48E-03 1.00E+00 2.25E-02 2.20E-01 4 4 "CDH2,NRXN1,NRXN2,MAGI2" GO: Biological Process GO:0071205 protein localization to juxtaparanode region of axon 1.48E-03 1.00E+00 2.25E-02 2.20E-01 4 4 "CNTNAP2,NFASC,EPB41L3,CNTN2" GO: Biological Process GO:0050923 regulation of negative chemotaxis 1.48E-03 1.00E+00 2.25E-02 2.20E-01 4 4 "SLIT2,PLXNA4,ROBO1,ROBO2" GO: Biological Process GO:0010817 regulation of hormone levels 1.50E-03 1.00E+00 2.28E-02 2.23E-01 129 550 "ABAT,ADCY5,ADORA1,ADORA3,AGT,PLA2G6,C1QTNF1,C1QTNF3,LTBP4,DDO,MADD,ARNTL,ARRB1,PDE8B,ATP1A1,BMPR1B,ARHGEF7,BTK,CACNA1A,CACNA1D,CACNA1E,CAMK2G,BRSK2,CCKBR,SCARB1,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,CRY2,CRYM,RIMS2,ECE2,C2CD2L,EDN1,EDN3,SIDT2,EGFR,PLEKHA1,HSD17B14,EPHA5,FGFR1,OGA,DKK3,GABBR1,ILDR2,GALR1,CPLX1,GCK,GDF9,PPARGC1A,DHRS4,GLUL,STARD3,PCSK1N,GNAS,PRLHR,GPER1,PCLO,RAPGEF4,NR3C1,HMGCR,HSD17B1,HTR2A,ICA1,IGF1,JAK2,KCNB1,KCNC2,KCNJ11,KCNMA1,SYTL4,SYT9,BCO1,MYO5A,MYT1,NELL2,NEUROD1,SLCO1C1,NNAT,NOS1,NUCB2,P2RY1,PAX6,PCSK1,PCSK5,PCSK2,PDE1C,PDE3B,PDGFRA,PFKFB2,ABCB1,SCHIP1,MED1,PPP3CA,PPP3CB,RELN,KLK6,PTPRN,PTPRN2,RFX3,RPE65,SOX8,SAFB,SCP2,SMPD3,SCG5,SYBU,SLCO1A2,SNAP25,TRERF1,SOX11,STX1A,ABCC8,TAC1,TACR1,TCF7L2,SIRT1,CHST8,TIAM1,TRH,STXBP4,TRPM2,VGF,VSNL1" GO: Biological Process GO:0086003 cardiac muscle cell contraction 1.54E-03 1.00E+00 2.33E-02 2.27E-01 19 52 "ANK2,ATP1A1,ATP1A2,ATP2A2,CACNA2D1,CACNB2,CAMK2D,AKAP6,NOS1AP,FGF12,KCNH2,CTNNA3,PDE4B,PDE4D,FXYD1,SCN2B,SCN4B,SCN3B,KCNE5" GO: Biological Process GO:0033275 actin-myosin filament sliding 1.60E-03 1.00E+00 2.42E-02 2.36E-01 16 41 "ACTN2,MYL6B,DBN1,DMD,MYLK2,MYBPC1,MYH3,MYH6,MYH7,MYL3,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4" GO: Biological Process GO:0045823 positive regulation of heart contraction 1.60E-03 1.00E+00 2.42E-02 2.36E-01 16 41 "ADRA1B,ADRB2,ATP1A1,ATP2A2,HCN2,CHGA,NOS1AP,EDN1,EDN3,HSP90AA1,NPPA,PDE4D,SCN3B,SIRT1,HEY2,TPM1" GO: Biological Process GO:0031646 positive regulation of neurological system process 1.64E-03 1.00E+00 2.47E-02 2.41E-01 12 27 "MYRF,TENM4,WASF3,RAPGEF4,FGFBP3,MAG,OPRL1,PTAFR,TF,DICER1,PARD3,TNR" GO: Biological Process GO:0021511 spinal cord patterning 1.64E-03 1.00E+00 2.47E-02 2.41E-01 12 27 "ASCL1,CHRD,NKX6-2,GLI2,NKX2-2,PAX6,RELN,RFX4,FUZ,IFT122,SOX1,IFT88" GO: Biological Process GO:0070727 cellular macromolecule localization 1.66E-03 1.00E+00 2.49E-02 2.43E-01 354 1676 "SYS1,ACTN2,ADAR,ADCY6,AXIN2,ADORA1,AP2A1,AP2A2,AP1B1,GPR158,AGT,TBC1D14,WDR35,OSBPL8,C1QTNF3,OGT,DPP10,ANK1,ANK2,ANK3,PPFIA1,CNTNAP1,KCNAB2,APC,CASK,SPTBN4,ARNTL,RGS20,ASPH,DACT3,NUMB,DYNLL1,ATM,ATP1B3,STX16,BARD1,BBS2,BID,BMP7,CDK5R1,AP1M1,RAB29,CACNA1A,CACNB2,KALRN,CAPN3,BRSK2,MAP7,CD81,AP4M1,ARHGEF2,CDC42,CDH2,DCLK1,EVI5L,LRWD1,COPB2,CHM,CHRM1,TAOK2,ZFYVE9,NRXN1,NRXN2,CLTA,CLTB,CLTC,FBXO7,HECTD1,NIPBL,RAB26,HOMER3,PICK1,AKAP6,CABP1,AKAP5,BAG4,MYRIP,ZNF385A,AKAP12,CRY2,CLIP3,SEC24C,CSNK1E,CNTNAP2,APPL1,RIMS2,USP6NL,PYGO1,MYADM,TCAF1,ZFYVE16,TBC1D5,TOMM20,DBN1,B3GAT3,KIAA0753,MAGI2,SGSM2,G3BP2,RABGAP1L,MTX3,DLG2,DLG3,DLG4,DMD,SHANK1,DPP6,DRD1,TOM1,DNAJB6,DNM1L,FIS1,TSPAN5,OPTN,SH3GLB1,EGFR,GOLGA7,TENM1,PAN3,DMTN,GPHN,STX2,ERBB2,ERBB4,APC2,VPS26C,DNAJC27,TLR7,RRAGB,EYA1,REEP2,TBC1D16,RACK1,TOMM40L,STRADA,SEC24B,FGF13,MEX3B,SEC23B,VTI1B,AGAP3,RGPD5,DCTN2,FOLR2,NBEA,SORBS1,ZBED3,NPTN,PRELID3A,AP4B1,OGA,FYB1,FYN,AHCYL1,RAPGEF6,DISC1,INPP5K,ARFIP1,GLRB,TNRC6A,OS9,DCLK2,FERMT2,GPM6B,FUT10,GPR26,GPER1,RFFL,GRIK2,GRIK5,GSN,KIF3A,PTPN5,KAT7,AP4S1,ATG4C,PACSIN2,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,HTR2A,IGF1,SCIN,JAK2,KCNA1,KCNB1,KCNN3,KLC1,KPNA5,IPO5,LAMP2,SYTL4,ZFYVE27,LYPLAL1,MDFI,MID1,MT3,MXI1,MYBPC1,MYO5A,MYO6,MYO7A,HNRNPM,NF1,NODAL,NUCB1,TBC1D25,CHAMP1,OGG1,P2RY1,ZDHHC22,TREM2,PALM,PAX6,PDE2A,PDPK1,ZDHHC8,PIK3R1,PKD1,SNX10,EXOSC10,PACSIN1,TNPO2,MED1,PPM1B,PPP2R2B,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PKIA,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,RELN,BCAS3,VPS13C,SYTL2,CNTLN,PTCH1,SPDL1,PTN,PEX2,PEX5,PID1,SH3TC2,RDX,MRAP2,RPL15,FBXW7,SGSM1,RPL38,LRRK2,RPS20,SYNDIG1,KCNIP3,WLS,CLIP1,STX1B,AP1AR,LRRTM4,SCP2,ELMOD1,CASC3,COPZ1,SCG5,NLGN1,DZIP1,ABLIM3,ZNF365,RPH3A,PEX26,RAB3GAP1,SIRT2,CDK5RAP3,SLC11A1,RTP5,NAPB,IFT122,RIMS1,KIF13A,SCN3B,TNIK,SPATA7,CLUAP1,NFASC,PBLD,CLASP2,EPB41L3,LRRC4,ERBIN,MPRIP,STAU1,CEP68,TTBK2,STX1A,KANK1,SULF2,STXBP1,SYNE2,ARHGEF9,VPS13A,ASTN2,MTCL1,CNTN2,FBXW11,TCF7L2,SYNE1,OBSL1,TEX15,TEK,ATP13A2,SIRT1,AP4E1,THRA,TIAM1,NACC2,TLR4,HEY2,PARD3,TP53BP2,STXBP4,TRPS1,ZMYND8,TSC2,RFTN2,TUB,HEPACAM,AMOT,UGT8,PDIA2,TOM1L2,CCDC14,TBC1D15,WIPF1,XPO1,ZIC1,ZBTB16,REEP1,MFF,EVI5,HPS4,SNX27,WNK3,GOPC,NUP214,NLRP3,TTC7A,FRMD6,AP3B2" GO: Biological Process GO:0021955 central nervous system neuron axonogenesis 1.69E-03 1.00E+00 2.54E-02 2.48E-01 14 34 "SPTBN4,DCLK1,CHRNB2,SLIT2,PLXNA4,DCC,ZEB2,EPHB1,GLI2,PTK2,MYCBP2,SZT2,NR2E1,PRDM8" GO: Biological Process GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.69E-03 1.00E+00 2.54E-02 2.48E-01 14 34 "APC,ARHGEF2,CLIP3,APC2,FGF13,EML4,STMN2,STMN1,MID1,MAP6D1,SGK1,SNCA,CLASP2,CLASP1" GO: Biological Process GO:0048013 ephrin receptor signaling pathway 1.70E-03 1.00E+00 2.54E-02 2.48E-01 28 88 "AP2A1,AP2A2,CDK5R1,ARHGEF7,KALRN,CDC42,CHN1,NGEF,SIPA1L1,DNM1,EFNA2,EFNA3,EFNB3,APH1A,EPHA5,EPHB1,FYN,GRIN1,RBPJ,GIT1,NTRK3,PAK3,PTK2,EPHA10,ITSN1,SS18,TIAM1,VAV2" GO: Biological Process GO:0014033 neural crest cell differentiation 1.72E-03 1.00E+00 2.57E-02 2.52E-01 27 84 "SEMA6A,SEMA7A,SEMA4G,NRP2,ZEB2,EDN1,EDN3,EDNRA,EDNRB,SEMA3D,ERBB4,SEMA6C,SEMA4D,GBX2,MEF2C,KITLG,PAX6,SEMA5B,MAPK3,RET,SOX8,SEMA6D,SOX10,SOX11,SEMA4A,DICER1,SEMA3B" GO: Biological Process GO:0048041 focal adhesion assembly 1.75E-03 1.00E+00 2.60E-02 2.54E-01 24 72 "ACTN1,ACTN2,EPB41L5,ARHGEF7,TAOK2,DAPK3,WDPCP,DMTN,PTK2B,DLC1,TESK2,SORBS1,FERMT2,GPM6B,ITGAV,LIMS1,ENPP2,PDPK1,BCAS3,PTK2,CLASP2,CLASP1,TEK,TSC1" GO: Biological Process GO:0007045 cell-substrate adherens junction assembly 1.75E-03 1.00E+00 2.60E-02 2.54E-01 24 72 "ACTN1,ACTN2,EPB41L5,ARHGEF7,TAOK2,DAPK3,WDPCP,DMTN,PTK2B,DLC1,TESK2,SORBS1,FERMT2,GPM6B,ITGAV,LIMS1,ENPP2,PDPK1,BCAS3,PTK2,CLASP2,CLASP1,TEK,TSC1" GO: Biological Process GO:1903793 positive regulation of anion transport 1.75E-03 1.00E+00 2.60E-02 2.54E-01 25 76 "ABAT,ADORA2A,AGT,PLA2G6,CCK,CHRNA4,CHRNB2,TCAF1,DPYSL2,EDN1,ATP8A1,GABBR1,ATP8A2,GRIK1,NR3C1,NAT8L,P2RX7,FXYD1,MAPK9,PTAFR,SLC6A1,RAB3GAP1,ACSL6,TRH,RTN4" GO: Biological Process GO:2001259 positive regulation of cation channel activity 1.76E-03 1.00E+00 2.61E-02 2.55E-01 17 45 "ASIC2,ACTN2,ANK2,ANK3,ASPH,CACNA2D1,CACNB2,CALM1,HAP1,AKAP7,AKAP6,NOS1AP,FGF14,KCNJ11,NPPA,HCN1,PIRT" GO: Biological Process GO:0097484 dendrite extension 1.89E-03 1.00E+00 2.80E-02 2.73E-01 11 24 "CPNE5,CPNE6,RIMS2,CDKL3,SYT3,SYT17,HNRNPK,CPNE9,RIMS1,SYT1,SYT4" GO: Biological Process GO:0032880 regulation of protein localization 1.94E-03 1.00E+00 2.86E-02 2.80E-01 231 1057 "ABAT,ACHE,ACTN2,ADCY5,AXIN2,ADORA2A,AGT,PLA2G6,C1QTNF3,OGT,DPP10,ANK3,CNIH2,PPFIA1,APBB1,KCNAB2,APC,EPB41L5,GPAM,MADD,ARHGDIA,ARHGDIG,ARNTL,ARRB1,RGS20,PDE8B,ASPH,DACT3,NUMB,DYNLL1,BARD1,BID,BMP7,CDK5R1,C5,RAB29,IL33,MMD2,CACNA1A,CACNA1D,CACNA1E,KALRN,BRSK2,CD38,CDC42,CDH2,DCLK1,CACNA2D2,CHRM1,NRXN1,CLTC,HECTD1,MAP4K4,CNR1,AKAP6,CABP1,AKAP5,BAG4,MYRIP,CLOCK,CLIP3,CSF1R,CSNK1E,APPL1,GAPVD1,TCAF1,KIAA0586,DBN1,B3GAT3,C2CD2L,SNAP91,G3BP2,RABGAP1L,DPP6,DNAJB6,DNM1L,FIS1,WDPCP,RASGRP1,SIDT2,SH3GLB1,CELSR3,EGFR,TENM1,DMTN,EPHA5,ERBB2,ERBB4,APC2,DNAJC27,TLR7,RACK1,FGR,VTI1B,SORBS1,ZBED3,TRIM16,NPTN,PRELID3A,OGA,FYN,NCKAP1,INPP5K,GCK,ARFIP1,GLUL,OS9,DCLK2,GNAS,GPM6B,GPR26,GPER1,RAPGEF4,GSN,KIF3A,PTPN5,KAT7,HMGB1,HMGCR,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,ATCAY,ICA1,IGF1,JAK2,KCNB1,KCNC2,KCNJ11,KCNN3,IPO5,STXBP5,SYTL4,LYPLAL1,SYT9,MDFI,SCAMP5,MXI1,MYBPC1,MYT1,HNRNPM,NEUROD1,NF1,NNAT,NODAL,NOS1,CLEC9A,NUCB1,OGG1,P2RX7,TREM2,PDE1C,PDE2A,PDE3B,PDPK1,PFKFB2,ZDHHC8,NLGN3,PIK3R1,PKD1,MED1,PPM1B,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PKIA,PRKCZ,MAPK7,MAPK8,BCAS3,PTCH1,PTN,TMEM231,PID1,SH3TC2,RDX,RFX3,FBXW7,LRRK2,LGR4,WLS,ELMOD1,IL17RB,SGK1,MYO18A,SYBU,NLGN1,ABLIM3,SIRT2,CDK5RAP3,SNAP25,MYCBP2,PBLD,TTBK2,STX1A,KANK1,SULF2,ABCC8,ASTN2,MTCL1,FBXW11,TCF7L2,TEX15,SIK3,TEK,ATP13A2,SIRT1,THRA,TIAM1,TLR4,TP53BP2,ZNF384,TRH,STXBP4,TRPM2,ZMYND8,CADM1,VSNL1,WIPF1,NSD2,WNT7A,XPO1,ZIC1,MFF,HPS4,WNK3,GOPC,NLRP3" GO: Biological Process GO:1901292 nucleoside phosphate catabolic process 1.94E-03 1.00E+00 2.86E-02 2.80E-01 35 118 "AMPD3,OGT,PDE8B,ENTPD2,ENTPD4,NCOR1,GDA,HDAC4,GMPR2,RACK1,PRKAG2,GCK,PPARGC1A,GPD1,HTR2A,IGF1,NCF2,OGG1,P2RX7,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ASPDH,PPARA,MAPK7,SMUG1,NEIL2,PRTFDC1,NT5M" GO: Biological Process GO:0097105 presynaptic membrane assembly 1.95E-03 1.00E+00 2.86E-02 2.80E-01 6 9 "NLGN4X,NRXN1,IL1RAPL1,NLGN3,PTPRD,NLGN1" GO: Biological Process GO:0098828 modulation of inhibitory postsynaptic potential 1.95E-03 1.00E+00 2.86E-02 2.80E-01 6 9 "ABAT,RIMS2,DBN1,NLGN3,IGSF9B,RIMS1" GO: Biological Process GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel 1.95E-03 1.00E+00 2.86E-02 2.80E-01 6 9 "CACNA2D1,CACNB2,CAMK2D,NOS1AP,NOS1,NPPA" GO: Biological Process GO:0010807 regulation of synaptic vesicle priming 1.95E-03 1.00E+00 2.86E-02 2.80E-01 6 9 "STX1B,RAB3GAP1,NAPB,RIMS1,STX1A,STXBP1" GO: Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 1.98E-03 1.00E+00 2.90E-02 2.84E-01 44 157 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,APLP1,CACNA1D,GPR37L1,CHGA,CHRM1,CHRM4,CNR1,DRD1,CALCRL,PRMT5,GABBR1,GALR1,GNAL,GNAO1,GNAS,MCHR1,GPR26,GPER1,GPR37,GRIK3,GRM2,GRM3,GRM7,GRM8,PTGDR2,HRH3,OPRL1,P2RY1,PDE4D,GNG2,PRKACB,PTHLH,PTH1R,SSTR2,P2RY12" GO: Biological Process GO:0071277 cellular response to calcium ion 1.99E-03 1.00E+00 2.91E-02 2.85E-01 19 53 "CPNE2,ASPH,CAMK2D,CAPN3,CPNE6,CRHBP,EDN1,RASA4,DMTN,RASGRP2,ADGRV1,ITPKB,KCNH1,MEF2C,NEUROD2,SLC25A23,CARF,RYR3,SYT1" GO: Biological Process GO:0006942 regulation of striated muscle contraction 2.09E-03 1.00E+00 3.06E-02 2.99E-01 27 85 "ADORA1,ADRA1B,ANK2,ASPH,ATP1A1,ATP1A2,ATP2A2,CALM1,CAMK2D,CHGA,AKAP6,NOS1AP,HDAC4,DMD,DMPK,HSP90AA1,MYLK2,CTNNA3,MYH7,MYL3,NOS1,NPPA,PDE4B,PDE4D,FXYD1,SLC8A1,SLC8A3" GO: Biological Process GO:0046847 filopodium assembly 2.11E-03 1.00E+00 3.08E-02 3.00E-01 21 61 "TTYH1,FGD2,NEURL1,CDC42,NRXN1,PPP1R16B,ARHGEF4,DBN1,TENM1,DMTN,STAU2,GAP43,GPM6A,PALM,BCAS3,PPP1R9A,NLGN1,FGD4,ZMYND8,PLPPR5,SPATA13" GO: Biological Process GO:0019933 cAMP-mediated signaling 2.11E-03 1.00E+00 3.08E-02 3.00E-01 21 61 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,KSR1,AKAP6,RIMS2,EPHA5,GNAS,PCLO,RAPGEF4,HTR5A,PDE2A,PDE3A,PDE3B,PDE4A,PDE4D,MAPK7,MGRN1,RASD2" GO: Biological Process GO:0031110 regulation of microtubule polymerization or depolymerization 2.11E-03 1.00E+00 3.08E-02 3.00E-01 21 61 "APC,ARHGEF2,GDA,CLIP3,APC2,FGF13,PSRC1,EML4,STMN2,STMN1,MAPT,MID1,MAPK8,MAP6D1,CLIP1,SGK1,SNCA,CLASP2,CLASP1,STMN4,SLC39A12" GO: Biological Process GO:0003299 muscle hypertrophy in response to stress 2.13E-03 1.00E+00 3.08E-02 3.00E-01 10 21 "ATP2A2,HDAC4,MEF2C,MYH6,MYH7,NPPA,PPP3CA,CAMTA2,HEY2,TRPC3" GO: Biological Process GO:0014898 cardiac muscle hypertrophy in response to stress 2.13E-03 1.00E+00 3.08E-02 3.00E-01 10 21 "ATP2A2,HDAC4,MEF2C,MYH6,MYH7,NPPA,PPP3CA,CAMTA2,HEY2,TRPC3" GO: Biological Process GO:0097503 sialylation 2.13E-03 1.00E+00 3.08E-02 3.00E-01 10 21 "ST3GAL5,ST8SIA3,ST3GAL6,ST6GALNAC3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" GO: Biological Process GO:0051590 positive regulation of neurotransmitter transport 2.13E-03 1.00E+00 3.08E-02 3.00E-01 10 21 "ADORA2A,CACNA1B,GPER1,NAT8L,STX1B,NLGN1,RAB3GAP1,RIMS1,SNCA,STX1A" GO: Biological Process GO:0060219 camera-type eye photoreceptor cell differentiation 2.13E-03 1.00E+00 3.08E-02 3.00E-01 10 21 "PROM1,CNGA3,SLC4A7,DSCAM,HCN1,SDK2,PTN,ROM1,RORB,SOX8" GO: Biological Process GO:0042491 inner ear auditory receptor cell differentiation 2.15E-03 1.00E+00 3.10E-02 3.03E-01 16 42 "ATP2B2,SLC4A7,USH1C,WDPCP,SEC24B,FGFR1,RBPJ,HES5,KCNMA1,MYCN,MYO6,MYO7A,STRC,HEY1,HEY2,PCDH15" GO: Biological Process GO:0010658 striated muscle cell apoptotic process 2.15E-03 1.00E+00 3.10E-02 3.03E-01 16 42 "AGT,APAF1,BMP7,CAMK2A,CAMK2D,QKI,HMGCR,HSP90AA1,JAK2,NACA,NFE2L2,PDPK1,MAPK8,RPS6KA2,SIRT1,HEY2" GO: Biological Process GO:0009150 purine ribonucleotide metabolic process 2.18E-03 1.00E+00 3.15E-02 3.07E-01 125 536 "SLC25A25,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,NME5,AK2,AMPD2,AMPD3,OGT,APLP1,CASK,PDE8B,ATP1A2,ATP2B2,ATP6V0A1,LDHD,CACNB4,CALM1,NFS1,CBS,CHGA,TJP2,SULT4A1,AKAP6,AKAP5,COX4I1,AKAP12,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,DRD1,DNM1L,EDN1,EDNRA,EDNRB,CALCRL,ENO2,COQ7,GPHN,GMPR2,PTK2B,RACK1,PRKAG2,ATP5PD,CAP2,GABBR1,GALR1,GART,GCK,SULT1C4,PPARGC1A,RUNDC3A,GNAL,GNAS,GPD1,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,ACOT7,HMGCR,HPCA,HTR2A,IGF1,NME9,KHK,MPP2,MYH3,MYH6,MYH7,P2RY13,NDUFA5,NF1,NME4,NOS1,NPPA,NPR2,NUCB2,OGDH,OPRL1,P2RX7,PALM,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,PGAM2,PKM,SLC25A23,PPARA,MAPK7,NDUFS7,PTHLH,PID1,MRAP2,LRRK2,HKDC1,MAGI3,OGDHL,SNCA,GPR161,VIPR2,PRTFDC1" GO: Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration 2.22E-03 1.00E+00 3.19E-02 3.12E-01 71 280 "ADCY5,ADCYAP1R1,ADRA1D,ADRA1B,AGT,PLA2G6,C1QTNF1,ANK2,ASPH,ATP1A2,CACNA1I,CACNA1G,CACNA1A,CACNA2D1,CALM1,HAP1,CAMK2D,CAPN3,CCKBR,CD38,AKAP6,AKAP5,DBI,DLG4,DMD,DRD1,FIS1,EDN1,EDNRA,EDNRB,PTK2B,NPTN,OGA,JPH4,GALR1,GCK,GNG3,MCHR1,GPER1,GRM1,HRH3,HMGB1,HTR2A,ITGAV,JAK2,MYO5A,NOS1,OPRL1,OXTR,P2RX7,P2RY1,PDE4D,PDGFRA,PDPK1,PKD1,PLCD1,PTH1R,RYR1,RYR3,RASA3,SLC8A2,SLC8A1,SLC8A3,SNCA,TAC1,TACR1,TPCN2,TRPC1,TRPC3,TRPM2,JPH3" GO: Biological Process GO:0015696 ammonium transport 2.28E-03 1.00E+00 3.27E-02 3.19E-01 35 119 "ABAT,SLC12A5,ADORA2A,ADORA3,SLC44A5,BTK,CACNA1A,CCKBR,CHRNA4,CHRNB2,CNR1,DRD1,EDN1,EDNRA,PRKAG2,GABBR1,GPM6B,HRH3,HTR2A,KCNA2,NAT8L,MAOB,NOS1,ABCB1,PRKAB2,PRKCB,SMPD3,SEC14L1,SLC6A8,SLC12A2,SLC22A4,SNCA,AZIN2,SLC44A1,RTN4" GO: Biological Process GO:0030334 regulation of cell migration 2.30E-03 1.00E+00 3.30E-02 3.22E-01 167 742 "ABR,ABHD6,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,SEMA7A,APC,EPB41L5,SHTN1,SEMA4G,ARHGAP5,ARHGDIA,CHRD,NUMB,ADAM15,NRP2,ARHGEF7,C5,IL33,LDLRAD4,CAMK2D,SPAG9,LDB2,KRIT1,SCARB1,NOG,ADGRG1,SLIT2,BAG4,CSF1,CSF1R,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,HDAC4,DAPK3,MAGI2,SRGAP3,DRD1,WDPCP,EDN1,EDN3,EDNRA,SEMA3D,EGFR,PLXNC1,DMTN,ERBB4,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FER,FGF1,OLFM1,FGFR1,FGR,SEMA6C,EVL,SEMA4D,FLT1,NRG3,GAB1,GCNT2,PPARGC1A,GPER1,RAPGEF4,RFFL,GSN,ATOH8,HAS2,PADI2,NCKAP1L,HMGB1,IGF1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INSM1,ITGAV,JAK2,KIT,LAMA2,KITLG,NBL1,NF1,NFE2L2,NODAL,NTRK3,DDR2,PAK3,PAX6,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,PIK3CD,PIK3R1,PLXNB1,PLXNB3,EPB41L4B,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRZ1,RDX,RET,ROBO1,FBXW7,PRR5L,SEMA6D,SELL,SGK1,DOCK10,FUZ,SLC8A1,SMARCA4,PBLD,CLASP2,SST,KANK1,SYNE2,PLCB1,TAC1,TACR1,SEMA4A,UNC5D,CLASP1,TEK,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,P2RY12,WNT7A,NDRG4,SEMA3B,RTN4,SPATA13" GO: Biological Process GO:0007173 epidermal growth factor receptor signaling pathway 2.31E-03 1.00E+00 3.31E-02 3.23E-01 38 132 "ADORA1,AP2A1,AP2A2,AGT,DGKD,APP,ZFYVE28,ARHGEF7,HAP1,NEURL1,REPS2,CDC42,EPS15L1,CLTA,NRG2,SOCS5,RASSF2,EGFR,EPS8,PTK2B,EFEMP1,FER,GAB1,GPER1,SHC3,PDPK1,PIK3C2A,PIK3R1,EPN1,SH3KBP1,PTK2,FBXW7,SH3GL2,KIF16B,ERBIN,UBC,MVB12B,SOCS4" GO: Biological Process GO:1902284 neuron projection extension involved in neuron projection guidance 2.32E-03 1.00E+00 3.31E-02 3.23E-01 17 46 "SEMA6A,ALCAM,SEMA7A,SEMA4G,NRP2,SLIT2,PLXNA4,DSCAM,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,SEMA6D,SLIT1,SEMA4A,SEMA3B" GO: Biological Process GO:0048846 axon extension involved in axon guidance 2.32E-03 1.00E+00 3.31E-02 3.23E-01 17 46 "SEMA6A,ALCAM,SEMA7A,SEMA4G,NRP2,SLIT2,PLXNA4,DSCAM,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,SEMA6D,SLIT1,SEMA4A,SEMA3B" GO: Biological Process GO:0045216 cell-cell junction organization 2.34E-03 1.00E+00 3.33E-02 3.26E-01 60 230 "ACTN1,ACTN2,NLGN4X,AGT,ANK2,PKP4,CNTNAP1,APC,EPB41L5,SHROOM2,NUMB,CADM3,ARHGEF7,CDC42,CDH2,CDH8,CDH10,CDH18,NUMBL,TAOK2,WHRN,NECTIN3,CSF1R,CTNND1,MYADM,DAPK3,PARD6A,WDPCP,DMTN,PTK2B,DLC1,TESK2,SORBS1,GJB1,FERMT2,GPM6B,ITGAV,KIFC3,LIMS1,AFDN,ENPP2,PDPK1,PKN2,BCAS3,PTK2,PTPRO,RDX,LIMS2,NFASC,CLASP2,EPB41L3,CLASP1,TEK,TJP1,PARD3,TSC1,CADM1,AMOT,UGT8,CADM2" GO: Biological Process GO:0031643 positive regulation of myelination 2.36E-03 1.00E+00 3.34E-02 3.27E-01 7 12 "MYRF,TENM4,WASF3,MAG,TF,DICER1,PARD3" GO: Biological Process GO:0031987 locomotion involved in locomotory behavior 2.36E-03 1.00E+00 3.34E-02 3.27E-01 7 12 "DBN1,RCAN1,RCAN2,GPR37,MYO5A,PPP3CB,ADGRL3" GO: Biological Process GO:2000322 regulation of glucocorticoid receptor signaling pathway 2.36E-03 1.00E+00 3.34E-02 3.27E-01 7 12 "ARNTL,CLOCK,CRY2,NR3C1,NTRK2,PPP5C,LMO3" GO: Biological Process GO:0001973 adenosine receptor signaling pathway 2.36E-03 1.00E+00 3.34E-02 3.27E-01 7 12 "ADCY5,ADORA1,ADORA2A,ADORA3,P2RY1,CNTN2,P2RY12" GO: Biological Process GO:0015698 inorganic anion transport 2.39E-03 1.00E+00 3.38E-02 3.30E-01 43 154 "TTYH1,SLC12A5,AQP6,SLC4A4,SLC22A6,CLCN3,CLCN4,SLC4A7,SLC4A8,CRY2,SLC12A6,FGFR1,IP6K2,PCYOX1,SLC37A3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,ADAMTS8,TTYH2,BEST3,FXYD1,SLC26A11,PTAFR,SLC4A3,SLC11A1,SLC12A2,SLC12A4,SLC20A2,SLC37A2,ANO4,ANO5,BEST1,SLC26A10,SLC17A7,SLC4A10" GO: Biological Process GO:0030318 melanocyte differentiation 2.39E-03 1.00E+00 3.38E-02 3.31E-01 12 28 "ZEB2,BLOC1S6,EDN3,EDNRB,KIT,MEF2C,KITLG,MITF,MYO5A,SOX10,ADAMTS9,HPS4" GO: Biological Process GO:0015849 organic acid transport 2.45E-03 1.00E+00 3.45E-02 3.37E-01 83 337 "ABAT,ADORA1,ADORA2A,AGT,PLA2G6,ABCD2,PPFIA4,PPFIA2,PPFIA1,PPFIA3,SLC7A14,NCOA1,ATP1A2,CACNA1A,CACNB4,CCK,SLC16A4,SLC22A6,SLC32A1,NCOR1,PNPLA8,DPYSL2,EDN1,SLC43A2,ACSL4,PRKAG2,FOLR2,GABBR1,STARD10,CPLX1,GLS,GRIK1,NR3C1,GRM2,GRM7,MFSD2A,HRH3,SLC6A17,KCNJ10,SFXN5,MYO6,NF1,SLCO1C1,NTRK2,P2RX7,SLC10A4,FXYD1,SLC36A4,PPARA,PRKAB2,MAPK9,SLC26A11,RAB3A,SLC6A15,RXRA,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,SLCO1A2,SLC22A4,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,ACSL6,SLC19A3,SPX,TRH,SLC13A3,SLC26A10,SLC38A1,SLC17A7,SLC17A6" GO: Biological Process GO:0051339 regulation of lyase activity 2.46E-03 1.00E+00 3.46E-02 3.38E-01 28 90 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,CALM1,AKAP5,DRD1,EDNRA,EDNRB,CAP2,GABBR1,GALR1,RUNDC3A,GNAL,GNAS,GPER1,GRM2,GRM3,GRM7,HRH3,HPCA,P2RY13,NF1,NOS1,PALM,VIPR2" GO: Biological Process GO:0031532 actin cytoskeleton reorganization 2.46E-03 1.00E+00 3.46E-02 3.38E-01 28 90 "CDC42BPA,ARHGDIA,BRSK2,CDC42BPB,CSF1R,SIPA1L1,DAPK3,FRY,DMTN,EPS8,PTK2B,FER,BAIAP2,ATP2C1,GSN,SMAP1,KIT,MKLN1,NTRK3,PDGFRA,PRKCZ,BCAS3,GDPD2,TNIK,SPTAN1,FRYL,TEK,RICTOR" GO: Biological Process GO:0019751 polyol metabolic process 2.47E-03 1.00E+00 3.47E-02 3.39E-01 33 111 "ADCYAP1R1,SYNJ1,SYNJ2,MTMR2,CALM1,MTMR7,PLCH2,IP6K1,PTK2B,IP6K2,IP6K3,INPP5K,GK,GPD2,GPER1,INPP1,INPP5B,ITPKA,ITPKB,OCRL,P2RY1,PLCB2,PLCD1,PTAFR,PTH1R,NUDT11,ACER3,SCP2,SNCA,NUDT10,PLCB1,SPHK2,PLD4" GO: Biological Process GO:0043524 negative regulation of neuron apoptotic process 2.58E-03 1.00E+00 3.62E-02 3.54E-01 44 159 "ADORA2A,AGT,CACNA1A,CRLF1,CNTFR,DLX1,OPTN,EN2,PTK2B,AGAP2,STAMBP,FYN,GABRA5,CHL1,GABRB3,PPARGC1A,TOX3,KDM2B,GRIK2,GRIN1,JAK2,LIG4,MEF2C,NRBP2,MT3,NTRK2,PDPK1,RETREG1,VSTM2L,PRKCG,OXR1,DRAXIN,ITSN1,AMBRA1,CPEB4,SNCB,SNCA,FAIM2,UNC5B,STXBP1,SIRT1,BHLHB9,XRCC4,MAP3K12" GO: Biological Process GO:0046942 carboxylic acid transport 2.60E-03 1.00E+00 3.65E-02 3.56E-01 82 333 "ABAT,ADORA1,ADORA2A,AGT,PLA2G6,ABCD2,PPFIA4,PPFIA2,PPFIA1,PPFIA3,SLC7A14,NCOA1,ATP1A2,CACNA1A,CACNB4,CCK,SLC16A4,SLC22A6,SLC32A1,NCOR1,PNPLA8,DPYSL2,EDN1,SLC43A2,ACSL4,PRKAG2,FOLR2,GABBR1,STARD10,CPLX1,GLS,GRIK1,NR3C1,GRM2,GRM7,MFSD2A,HRH3,SLC6A17,KCNJ10,SFXN5,MYO6,NF1,SLCO1C1,NTRK2,P2RX7,SLC10A4,SLC36A4,PPARA,PRKAB2,MAPK9,SLC26A11,RAB3A,SLC6A15,RXRA,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,RAB3GAP1,SLC11A1,SLCO1A2,SLC22A4,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYT1,ACSL6,SLC19A3,SPX,TRH,SLC13A3,SLC26A10,SLC38A1,SLC17A7,SLC17A6" GO: Biological Process GO:0030042 actin filament depolymerization 2.61E-03 1.00E+00 3.65E-02 3.57E-01 20 58 "ACTN2,ADD1,ADD2,SHROOM2,SPTBN4,CFL2,MICAL2,DMTN,EPS8,EVL,GSN,SCIN,DBNL,TMOD2,RDX,SPTAN1,SPTB,TMOD1,PLEKHH2,MICAL1" GO: Biological Process GO:0007212 dopamine receptor signaling pathway 2.63E-03 1.00E+00 3.67E-02 3.58E-01 15 39 "ADCY5,ADCY6,ARRB2,RGS9,CALY,DRD1,PRMT5,NSG2,NSG1,GNAL,GNAO1,GNAS,PALM,GNG2,LRRK2" GO: Biological Process GO:0031281 positive regulation of cyclase activity 2.65E-03 1.00E+00 3.69E-02 3.61E-01 21 62 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,CALM1,AKAP5,DRD1,EDNRA,CAP2,RUNDC3A,GNAL,GNAS,GPER1,HPCA,NF1,NOS1,MAPK3,MAPK8,VIPR2" GO: Biological Process GO:0003407 neural retina development 2.65E-03 1.00E+00 3.69E-02 3.61E-01 21 62 "ATP2B1,PROM1,CALB1,CNGA3,SLC4A7,DSCAM,MEGF11,ATP8A2,GPM6A,NEUROD1,HCN1,SDK2,FAT3,PTN,ROM1,RORB,RPE65,SOX8,SMARCA4,SMARCD3,SLC17A7" GO: Biological Process GO:0031333 negative regulation of protein complex assembly 2.65E-03 1.00E+00 3.69E-02 3.61E-01 35 120 "ADD1,ADD2,SPTBN4,LDLRAD4,CDC42,SLIT2,CLU,CLIP3,MYADM,DMTN,EPS8,EVL,STMN2,GSN,HMGB1,SCIN,STMN1,DBNL,TMOD2,PRKCZ,PEX5,RDX,SGK1,FHOD3,SIRT2,SNCA,SPTAN1,SPTB,KANK1,THRA,HEY2,TMOD1,TRIM9,TFIP11,PMEPA1" GO: Biological Process GO:0021513 spinal cord dorsal/ventral patterning 2.81E-03 1.00E+00 3.91E-02 3.82E-01 11 25 "ASCL1,CHRD,NKX6-2,GLI2,NKX2-2,PAX6,RFX4,FUZ,IFT122,SOX1,IFT88" GO: Biological Process GO:0044091 membrane biogenesis 2.84E-03 1.00E+00 3.93E-02 3.84E-01 13 32 "NLGN4X,ANK3,CDH2,NRXN1,NRXN2,CLIP3,MAGI2,STX2,IL1RAPL1,PACSIN2,NLGN3,PTPRD,NLGN1" GO: Biological Process GO:0048639 positive regulation of developmental growth 2.84E-03 1.00E+00 3.93E-02 3.84E-01 49 182 "ADRB2,AGT,SEMA7A,GPAM,SHTN1,CPNE5,SPTBN4,BBS2,CAPN3,CACNA2D2,CPNE6,NIPBL,AKAP6,CSF1,RIMS2,IST1,DBN1,DSCAM,EIF4G2,ERBB4,FGFR1,SEMA4D,SYT3,CELF1,SYT17,DISC1,ATP8A2,GHR,NR3C1,HNRNPK,IGF1,RBPJ,L1CAM,MAPT,MEF2C,CPNE9,NACA,NCAM1,NTRK3,POU3F2,PROX1,PEX5,ARX,RIMS1,SOX15,PLCB1,SYT1,SYT4,HEY2" GO: Biological Process GO:0098661 inorganic anion transmembrane transport 2.89E-03 1.00E+00 4.00E-02 3.91E-01 33 112 "TTYH1,SLC12A5,CLCN3,CLCN4,SLC12A6,PCYOX1,SLC37A3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,ADAMTS8,TTYH2,BEST3,FXYD1,SLC26A11,PTAFR,SLC4A3,SLC12A2,SLC12A4,SLC20A2,SLC37A2,ANO4,ANO5,BEST1,SLC26A10,SLC17A7" GO: Biological Process GO:1902476 chloride transmembrane transport 2.94E-03 1.00E+00 4.06E-02 3.97E-01 28 91 "TTYH1,SLC12A5,CLCN3,CLCN4,SLC12A6,PCYOX1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,TTYH2,BEST3,FXYD1,SLC26A11,SLC4A3,SLC12A2,SLC12A4,ANO4,ANO5,BEST1,SLC26A10,SLC17A7" GO: Biological Process GO:0021587 cerebellum morphogenesis 3.02E-03 1.00E+00 4.16E-02 4.07E-01 17 47 "ATP2B2,CACNA1A,CBLN1,CBS,NRXN1,WHRN,CEND1,GLI2,KNDC1,NFIX,SERPINE2,PROX1,RFX4,ATXN2,FAIM2,AGTPBP1,WNT7A" GO: Biological Process GO:0034613 cellular protein localization 3.06E-03 1.00E+00 4.21E-02 4.11E-01 349 1666 "SYS1,ACTN2,ADAR,ADCY6,AXIN2,ADORA1,AP2A1,AP2A2,AP1B1,GPR158,AGT,TBC1D14,WDR35,OSBPL8,C1QTNF3,OGT,DPP10,ANK1,ANK2,ANK3,PPFIA1,CNTNAP1,KCNAB2,APC,CASK,SPTBN4,ARNTL,RGS20,ASPH,DACT3,NUMB,DYNLL1,ATP1B3,STX16,BARD1,BBS2,BID,BMP7,CDK5R1,AP1M1,RAB29,CACNA1A,CACNB2,KALRN,CAPN3,BRSK2,MAP7,CD81,AP4M1,ARHGEF2,CDC42,CDH2,DCLK1,EVI5L,LRWD1,COPB2,CHM,CHRM1,TAOK2,ZFYVE9,NRXN1,NRXN2,CLTA,CLTB,CLTC,FBXO7,HECTD1,NIPBL,RAB26,HOMER3,PICK1,AKAP6,CABP1,AKAP5,BAG4,MYRIP,AKAP12,CRY2,CLIP3,SEC24C,CSNK1E,CNTNAP2,APPL1,RIMS2,USP6NL,PYGO1,MYADM,TCAF1,ZFYVE16,TBC1D5,TOMM20,DBN1,B3GAT3,KIAA0753,MAGI2,SGSM2,G3BP2,RABGAP1L,MTX3,DLG2,DLG3,DLG4,DMD,SHANK1,DPP6,DRD1,TOM1,DNAJB6,DNM1L,FIS1,TSPAN5,OPTN,SH3GLB1,EGFR,GOLGA7,TENM1,PAN3,DMTN,GPHN,STX2,ERBB2,ERBB4,APC2,VPS26C,DNAJC27,TLR7,RRAGB,EYA1,REEP2,TBC1D16,RACK1,TOMM40L,STRADA,SEC24B,FGF13,MEX3B,SEC23B,VTI1B,AGAP3,RGPD5,DCTN2,FOLR2,NBEA,SORBS1,ZBED3,NPTN,PRELID3A,AP4B1,OGA,FYB1,FYN,AHCYL1,RAPGEF6,DISC1,INPP5K,ARFIP1,GLRB,TNRC6A,OS9,DCLK2,FERMT2,GPM6B,FUT10,GPR26,GPER1,RFFL,GRIK2,GRIK5,GSN,KIF3A,PTPN5,KAT7,AP4S1,ATG4C,PACSIN2,HNMT,HNRNPK,HPCA,HSPA1L,HSP90AA1,HTR2A,IGF1,SCIN,JAK2,KCNA1,KCNB1,KCNN3,KLC1,KPNA5,IPO5,LAMP2,SYTL4,ZFYVE27,LYPLAL1,MDFI,MID1,MT3,MXI1,MYBPC1,MYO5A,MYO6,MYO7A,HNRNPM,NF1,NODAL,NUCB1,TBC1D25,CHAMP1,OGG1,P2RY1,ZDHHC22,TREM2,PALM,PAX6,PDE2A,PDPK1,ZDHHC8,PIK3R1,PKD1,SNX10,PACSIN1,TNPO2,MED1,PPM1B,PPP2R2B,PPP3CA,PPP3CB,PPP3CC,RANBP3L,PKIA,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,RELN,BCAS3,VPS13C,SYTL2,CNTLN,PTCH1,SPDL1,PTN,PEX2,PEX5,PID1,SH3TC2,RDX,MRAP2,RPL15,FBXW7,SGSM1,RPL38,LRRK2,RPS20,SYNDIG1,KCNIP3,WLS,CLIP1,STX1B,AP1AR,LRRTM4,SCP2,ELMOD1,COPZ1,SCG5,NLGN1,DZIP1,ABLIM3,ZNF365,RPH3A,PEX26,RAB3GAP1,SIRT2,CDK5RAP3,SLC11A1,RTP5,NAPB,IFT122,RIMS1,KIF13A,SCN3B,TNIK,SPATA7,CLUAP1,NFASC,PBLD,CLASP2,EPB41L3,LRRC4,ERBIN,MPRIP,CEP68,TTBK2,STX1A,KANK1,SULF2,STXBP1,SYNE2,ARHGEF9,VPS13A,ASTN2,MTCL1,CNTN2,FBXW11,TCF7L2,SYNE1,OBSL1,TEX15,TEK,ATP13A2,SIRT1,AP4E1,THRA,TIAM1,NACC2,TLR4,HEY2,PARD3,TP53BP2,STXBP4,TRPS1,ZMYND8,TSC2,RFTN2,TUB,HEPACAM,AMOT,UGT8,PDIA2,TOM1L2,CCDC14,TBC1D15,WIPF1,XPO1,ZIC1,ZBTB16,REEP1,MFF,EVI5,HPS4,SNX27,WNK3,GOPC,NUP214,NLRP3,TTC7A,FRMD6,AP3B2" GO: Biological Process GO:0021536 diencephalon development 3.10E-03 1.00E+00 4.27E-02 4.17E-01 26 83 "NR0B1,NCOA1,NRP2,HAP1,NOG,CHRNB2,NCOR1,CNTNAP2,ZEB2,OLIG2,GBX2,GLI2,RBPJ,KCNC1,KCNC2,NCAM1,OGDH,PAX6,POU3F2,PTN,SALL1,ARX,RAB3GAP1,SOX2,SOX3,TCF7L2" GO: Biological Process GO:0009259 ribonucleotide metabolic process 3.13E-03 1.00E+00 4.29E-02 4.19E-01 127 551 "SLC25A25,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRB2,NME5,AK2,AMPD2,AMPD3,OGT,APLP1,UPRT,CASK,PDE8B,ATP1A2,ATP2B2,ATP6V0A1,LDHD,CACNB4,CALM1,NFS1,CBS,CHGA,TJP2,SULT4A1,AKAP6,AKAP5,COX4I1,ENTPD4,AKAP12,NCOR1,HDAC4,AK5,DLG2,DLG3,DLG4,DRD1,DNM1L,EDN1,EDNRA,EDNRB,CALCRL,ENO2,COQ7,GPHN,GMPR2,PTK2B,RACK1,PRKAG2,ATP5PD,CAP2,GABBR1,GALR1,GART,GCK,SULT1C4,PPARGC1A,RUNDC3A,GNAL,GNAS,GPD1,GPER1,GRM2,GRM3,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,ACOT7,HMGCR,HPCA,HTR2A,IGF1,NME9,KHK,MPP2,MYH3,MYH6,MYH7,P2RY13,NDUFA5,NF1,NME4,NOS1,NPPA,NPR2,NUCB2,OGDH,OPRL1,P2RX7,PALM,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PFKFB2,PFKFB3,PFKFB4,OLA1,PFKP,PGAM2,PKM,SLC25A23,PPARA,MAPK7,NDUFS7,PTHLH,PID1,MRAP2,LRRK2,HKDC1,MAGI3,OGDHL,SNCA,GPR161,VIPR2,PRTFDC1" GO: Biological Process GO:0021575 hindbrain morphogenesis 3.14E-03 1.00E+00 4.30E-02 4.20E-01 18 51 "ATP2B2,CACNA1A,CBLN1,CBS,NRXN1,WHRN,CEND1,DLC1,GLI2,KNDC1,NFIX,SERPINE2,PROX1,RFX4,ATXN2,FAIM2,AGTPBP1,WNT7A" GO: Biological Process GO:0048839 inner ear development 3.16E-03 1.00E+00 4.30E-02 4.20E-01 55 210 "ABR,LGR5,ATP2B2,WHRN,SLC4A7,LRIG1,GSDME,PLPPR4,USH1C,WDPCP,ADGRV1,EYA1,SEC24B,FGFR1,FGFR3,FOXG1,GABRA5,GABRB3,ATP8A2,GBX2,GLI2,CECR2,KIF3A,HPCA,IFI16,IGF1,RBPJ,HES5,KCNK2,KCNK3,KCNMA1,MYCN,MYO6,MYO7A,NEUROD1,NTRK3,CYTL1,TMIE,PRRX1,POU3F4,PROX1,STRC,FAT4,SOX2,STOX1,ZEB1,RPGRIP1L,DICER1,HEY1,HEY2,ZIC1,PCDH15,FZD3,VANGL2,IFT88" GO: Biological Process GO:0021626 central nervous system maturation 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "CDK5R1,CDK5R2,CACNA1A,CEND1,GRIN1" GO: Biological Process GO:2000807 regulation of synaptic vesicle clustering 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "CDH2,MAGI2,PCDH17,NLGN3,NLGN1" GO: Biological Process GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "GRIK3,GRM2,GRM3,GRM7,GRM8" GO: Biological Process GO:0021578 hindbrain maturation 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "CDK5R1,CDK5R2,CACNA1A,CEND1,GRIN1" GO: Biological Process GO:0090527 actin filament reorganization 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "FRY,DMTN,GSN,GDPD2,FRYL" GO: Biological Process GO:0023041 neuronal signal transduction 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "NRXN1,CLU,OLFM1,KCNA1,NLGN1" GO: Biological Process GO:0030913 paranodal junction assembly 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "ANK2,CNTNAP1,NFASC,EPB41L3,UGT8" GO: Biological Process GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 3.18E-03 1.00E+00 4.30E-02 4.20E-01 5 7 "ASCL1,TBR1,PAX6,FEZF2,SATB2" GO: Biological Process GO:0046839 phospholipid dephosphorylation 3.20E-03 1.00E+00 4.33E-02 4.23E-01 14 36 "SYNJ1,SYNJ2,MTMR3,MTMR2,MTMR7,PLPPR4,INPP5K,INPP5B,OCRL,PLPPR1,PLPPR3,PLPPR2,PLPP4,PLPPR5" GO: Biological Process GO:1902882 regulation of response to oxidative stress 3.23E-03 1.00E+00 4.35E-02 4.25E-01 24 75 "NME5,BMP7,NGB,RGN,GPR37L1,RACK1,FOXO3,SESN1,GFER,GPR37,HP,SESN3,MT3,NFE2L2,MAPK7,FBXW7,LRRK2,SFPQ,SNCA,STOX1,SZT2,SIRT1,TRPM2,PDIA2" GO: Biological Process GO:0050922 negative regulation of chemotaxis 3.23E-03 1.00E+00 4.35E-02 4.25E-01 19 55 "SEMA6A,SEMA7A,SEMA4G,C5,SLIT2,SEMA3D,SEMA6C,SEMA4D,PADI2,NBL1,SEMA5B,PTPRO,ROBO1,ROBO2,SEMA6D,ST6GAL1,SLIT1,SEMA4A,SEMA3B" GO: Biological Process GO:0021801 cerebral cortex radial glia guided migration 3.26E-03 1.00E+00 4.38E-02 4.28E-01 10 22 "CDK5R1,CDK5R2,ADGRG1,FOXG1,DISC1,MBOAT7,RELN,NR2E1,LRP8,RTN4" GO: Biological Process GO:0022030 telencephalon glial cell migration 3.26E-03 1.00E+00 4.38E-02 4.28E-01 10 22 "CDK5R1,CDK5R2,ADGRG1,FOXG1,DISC1,MBOAT7,RELN,NR2E1,LRP8,RTN4" GO: Biological Process GO:0044849 estrous cycle 3.26E-03 1.00E+00 4.38E-02 4.28E-01 10 22 "ADRB2,NCOA1,CCKBR,CLU,ERBB2,HAS2,OPRL1,OXTR,PTN,TRPM2" GO: Biological Process GO:0060042 retina morphogenesis in camera-type eye 3.28E-03 1.00E+00 4.39E-02 4.29E-01 20 59 "PROM1,CALB1,CNGA3,SLC4A7,NECTIN3,CDON,DSCAM,MEGF11,ATP8A2,HCN1,SDK2,FAT3,PROX1,PTN,ROM1,RORB,RPE65,SOX8,SOX2,CRB2" GO: Biological Process GO:0006906 vesicle fusion 3.28E-03 1.00E+00 4.39E-02 4.29E-01 42 152 "TBC1D14,SYT13,DOC2A,STX16,SYT6,EVI5L,USP6NL,SNPH,TBC1D5,BLOC1S6,SGSM2,RABGAP1L,SYT15,STX2,TBC1D16,VTI1B,ANKFY1,SYT3,TMEM175,SYT17,GRIK5,C2CD4C,SYTL4,SYT9,TBC1D25,RAB39A,SYTL2,RAB3A,SGSM1,STX1B,RPH3A,SNAP25,STX1A,STXBP1,SYT11,VAMP1,SYT1,SYT4,SYT5,TBC1D15,TRIM9,EVI5" GO: Biological Process GO:2000145 regulation of cell motility 3.31E-03 1.00E+00 4.44E-02 4.33E-01 176 793 "ABR,ABHD6,ADORA1,ADORA3,MTUS1,AGT,HACE1,OSBPL8,SEMA6A,SEMA7A,APC,EPB41L5,SHTN1,SEMA4G,ARHGAP5,ARHGDIA,CHRD,NUMB,ADAM15,BBS2,NRP2,ARHGEF7,C5,IL33,LDLRAD4,CAMK2D,SPAG9,LDB2,KRIT1,RGN,SCARB1,CD81,NOG,ADGRG1,SLIT2,BAG4,NRG2,CSF1,CSF1R,PLXNA4,SDC3,CX3CR1,DOCK4,HDAC9,MYADM,TCAF1,HDAC4,DAPK3,MAGI2,SRGAP3,DRD1,WDPCP,EDN1,EDN3,EDNRA,SEMA3D,EGFR,PLXNC1,DMTN,ERBB2,ERBB4,F3,PTK2B,EFEMP1,DLC1,ATP8A1,RACK1,FER,FGF1,OLFM1,FGFR1,FGR,SEMA6C,EVL,SEMA4D,FLT1,NRG3,GAB1,GCNT2,PPARGC1A,GPER1,RAPGEF4,RFFL,GSN,ATOH8,HAS2,PADI2,NCKAP1L,HMGB1,IGF1,NKD1,RBPJ,DOCK7,IL6R,IL6ST,SCRT2,IL12A,INSM1,ITGAV,JAK2,KIT,LAMA2,KITLG,NBL1,NF1,NFE2L2,NODAL,NTRK3,DDR2,PAK3,PAX6,PDGFRA,ENPP2,PDPK1,GPR173,SERPINE2,SEMA5B,PIK3CD,PIK3R1,PLXNB1,PLXNB3,EPB41L4B,PKN2,MAPK8,PROX1,RELN,BCAS3,LAMA1,PTAFR,PTK2,PTN,PTPRG,PTPRZ1,RDX,RET,ROBO1,FBXW7,PRR5L,AP1AR,SEMA6D,SELL,SGK1,DOCK10,FUZ,SLC8A1,SMARCA4,PBLD,CLASP2,SST,KANK1,SYNE2,PLCB1,TAC1,TACR1,SEMA4A,UNC5D,CLASP1,TEK,TF,TGFBR3,THBS4,TIAM1,TIE1,NR2E1,TPM1,ELP5,TMEFF2,SGK3,AMOT,FLRT2,P2RY12,WNT7A,NDRG4,SEMA3B,RTN4,SPATA13" GO: Biological Process GO:0060041 retina development in camera-type eye 3.34E-03 1.00E+00 4.46E-02 4.36E-01 44 161 "ACHE,APC,ATP2B1,PROM1,BMPR1B,CALB1,LHX2,VAX2,CNGA3,SLC4A7,NECTIN3,CDON,DSCAM,MEGF11,ATP8A2,GPM6A,HPCA,NDP,NEUROD1,HCN1,NTRK2,PAX6,PDGFRA,SDK2,FAT3,MED1,PROX1,LAMA1,PTN,RET,ROM1,RORB,RPE65,SOX8,SMARCA4,SMARCD3,SOX2,JMJD6,AGTPBP1,NR2E1,TUB,CRB2,CELF4,SLC17A7" GO: Biological Process GO:0042692 muscle cell differentiation 3.35E-03 1.00E+00 4.47E-02 4.37E-01 98 412 "ACADM,ACTN2,ARID1A,AGT,MRTFA,BIN1,ANK2,PI16,ATP2A2,ADGRB3,CFLAR,CACNB4,CAMK2D,CAPN3,CAST,SPAG9,CDC42,CDH2,CACNA2D2,CFL2,QKI,AKAP6,HINFP,CMTM5,CTH,BOC,HDAC9,RIPOR2,HDAC4,MAML1,MYEF2,DMD,DMPK,CDON,RCAN1,EDN1,EDNRB,PLEKHO1,SPEG,FLNC,PDLIM5,MEGF10,DNER,MSTN,GPER1,PLPP7,NR3C1,BVES,HMGCR,MYLK2,IGF1,RBPJ,KCNH1,KIT,MBNL1,MEF2C,MYH3,MYH6,NACA,NOS1,NPPA,PDGFRA,TMOD2,PIK3R1,TNPO2,PPP3CA,PROX1,PBRM1,SOX8,RXRA,RYR1,MAPK12,SOX6,FHOD3,SLC8A1,EPC1,SMARCA4,SMARCD3,SOX15,MESP1,PLCB1,TCF7L2,ZEB1,SYNE1,OBSL1,DICER1,THRA,HEY1,HEY2,TMOD1,TPM1,NR2C2,TSC1,HIRA,UCHL1,KCNAB1,VANGL2,IFT88" GO: Biological Process GO:0090087 regulation of peptide transport 3.35E-03 1.00E+00 4.47E-02 4.37E-01 72 289 "ABAT,ADCY5,ADORA1,PLA2G6,C1QTNF3,MADD,ARNTL,ARRB1,PDE8B,BMP7,ARHGEF7,CACNA1A,CACNA1D,CACNA1E,BRSK2,CCKBR,CD38,CACNA2D2,NRXN1,MAP4K4,CNR1,MYRIP,CLOCK,CRHBP,C2CD2L,G3BP2,SIDT2,EGFR,EPHA5,TLR7,OGA,GABBR1,GCK,GLUL,GNAS,GPER1,RAPGEF4,HMGCR,ICA1,JAK2,KCNB1,KCNC2,KCNJ11,SYTL4,SYT9,MYT1,NEUROD1,NNAT,NOS1,NUCB2,PAX6,PDE1C,PDE3B,PFKFB2,PPM1B,PPP3CA,PPP3CB,RFX3,SYBU,SNAP25,STX1A,ABCC8,FBXW11,TCF7L2,SIRT1,TIAM1,TLR4,TRH,STXBP4,TRPM2,VSNL1,NLRP3" GO: Biological Process GO:0010942 positive regulation of cell death 3.51E-03 1.00E+00 4.66E-02 4.56E-01 156 695 "ABR,RBM10,PLEKHG5,AXIN2,ADORA2A,ADRB2,AGT,PLA2G6,SPOP,SRPX,BIN1,FGD2,APAF1,APBB1,APBB2,APC,ARRB1,ASCL1,MARK4,NCOA1,CCAR2,DYNLL1,ATM,RIPK1,BARD1,BID,BMP7,BMPR1B,CDK5R1,ARHGEF7,KALRN,CAMK2A,CAMK2B,CAMK2D,CCK,AIFM1,NEURL1,ARHGEF2,CDC42,SLIT2,CLU,NGEF,ARHGEF6,CNR1,MAGED1,CLIP3,ARHGEF4,HDAC4,RASSF2,DAPK1,DAPK3,TIAM2,GSDME,DNM2,CASP8AP2,DNM1L,FIS1,EEF1A2,SH3GLB1,APH1A,ING4,ERBB4,F3,DLC1,RACK1,FGFR3,IP6K2,FOXO3,APOPT1,PNMA2,PPARGC1A,RNPS1,GPER1,GRIK2,GRIK5,GRIN1,NR3C1,GSN,PTPN5,HBA1,HMGB1,HMGCR,HP,SCIN,IL12A,JAK2,KCNK2,KCNMA1,MEF2C,MT3,MYCN,NCF2,NELL1,NEUROD1,NF1,NODAL,NOS1,SLC11A2,NTRK3,P2RX7,PAK3,PDCD2,PNMA3,ING3,SEPT4,PPP2R2B,PTPA,PPP3CC,MAPK8,MAPK9,PRODH,PTN,PTPRZ1,RASGRF2,RET,ROBO1,FBXW7,RPS6KA2,LRRK2,RXRA,S100B,CSRNP3,SCP2,FNIP1,SFPQ,ITSN1,SIRT2,SNCA,UNC5B,CDK19,SRPK2,FGD4,ARHGEF9,MCF2L,TCF7L2,ARHGEF12,SIRT1,ITGB3BP,ZMAT3,TIAM1,NACC2,TLR4,TP53BP2,ZNF346,TRIO,TRPM2,TRPS1,UBC,BCL2L13,MTCH1,VAV1,VAV2,ZBTB16,MFF,ITM2C,NLRP3" GO: Biological Process GO:0003018 vascular process in circulatory system 3.56E-03 1.00E+00 4.73E-02 4.62E-01 53 202 "ABR,ASIC2,ADCY6,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,ATP1A2,BBS2,CACNA1G,CBS,CD38,CHGA,CHRM1,SLIT2,CPS1,DOCK4,DRD1,EDN1,EDN3,EDNRA,EDNRB,EGFR,KCNMB2,MRVI1,KCNMB4,GPER1,NR3C1,GUCY1A1,HMGCR,HTR2A,KCNMA1,FGFBP3,NOS1,NPPA,OXTR,P2RY1,PDE2A,PDE3A,PIK3C2A,PTAFR,PTK2,RAP1GDS1,SMPD3,SLC8A1,TACR1,TEK,SIRT1,TGFBR3,AMOT" GO: Biological Process GO:0007187 "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" 3.60E-03 1.00E+00 4.77E-02 4.66E-01 49 184 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,APLP1,CACNA1D,GPR37L1,CHGA,CHRM1,CHRM4,CNR1,DRD1,CALCRL,PRMT5,GABBR1,GALR1,GNAL,GNAO1,GNAS,MCHR1,GPR26,GPER1,GPR37,GRIK3,GRM2,GRM3,GRM7,GRM8,PTGDR2,HRH3,HTR5A,NPY,OPRL1,P2RY1,PDE4D,GNG2,PRKACB,PTHLH,PTH1R,GKAP1,SSTR1,SSTR2,P2RY12" GO: Biological Process GO:0010941 regulation of cell death 3.63E-03 1.00E+00 4.81E-02 4.69E-01 345 1650 "KCNH8,ABR,ASIC2,RBM10,ACTN1,ACTN2,ADAR,PLEKHG5,ADCYAP1R1,AXIN2,ADORA1,ADORA2A,ADRB2,AGT,NME5,PLA2G6,SPOP,SRPX,ALK,MRTFA,BIN1,OGT,FGD2,APAF1,APBB1,APBB2,APC,GPAM,API5,PDXK,MADD,ARHGDIA,ARRB1,ARRB2,ASCL1,MARK4,NCOA1,CCAR2,DYNLL1,ATM,RIPK1,BARD1,BCL2L2,BID,BLM,CFLAR,BMP7,BMPR1B,CDK5R1,ARHGEF7,NAE1,BTK,CACNA1A,KALRN,NGB,CAMK2A,CAMK2B,CAMK2D,CAPN3,CAST,CBS,CCK,KRIT1,RGN,AIFM1,ARHGEF1,CD38,NEURL1,ARHGEF2,CDC42,NOG,CRLF1,GPR37L1,CHGA,CHM,SLIT2,CLU,NGEF,QKI,MAP4K4,ARHGEF6,CNR1,PICK1,CNTFR,SLC25A27,MAGED1,BAG4,ZNF385A,CLIP3,CSF1R,CST3,CTH,ARHGEF4,CX3CR1,NOS1AP,HDAC4,RASSF2,INTS1,DAPK1,DAPK3,DCC,TIAM2,GSDME,ARNT2,DLX1,DNM2,CASP8AP2,DNAJB6,DNM1L,FIS1,EDN1,EDNRA,EDNRB,EEF1A2,SGK2,HIPK3,FEM1B,EEF1D,OPTN,SH3GLB1,APH1A,EGFR,EGR3,ING4,EN2,EPHB1,ERBB2,ERBB4,EYA1,F3,PTK2B,DLC1,RACK1,FGFR1,FGFR3,IP6K2,AGAP2,FOXO3,SEMA4D,APOPT1,STAMBP,PNMA2,FYN,GABRA5,CHL1,GABRB3,ZMYND11,GDF1,MSTN,GDF9,GFER,GHR,PPARGC1A,MALT1,RNPS1,GLI2,GPR75,TOX3,KDM2B,GPER1,GPR37,RFFL,GRIK2,GRIK5,GRIN1,NR3C1,GRM7,GSN,PTPN5,IRAK3,MAEL,HBA1,NCKAP1L,HMGB1,HMGCR,HNRNPK,HP,IGF1,RBPJ,SCIN,IL6ST,SCRT2,IL12A,ITGAV,ITPKB,JAK2,KCNB1,KCNK2,KCNMA1,KIT,LIFR,LIG4,LIMS1,PACRG,MDM4,MEF2C,KITLG,MITF,NRBP2,MT3,MYCN,NACA,NCAM1,NCF2,NELL1,NEUROD1,NF1,NFE2L2,NME4,NODAL,NOS1,SLC11A2,NTRK2,NTRK3,OGG1,OPA1,P2RX7,PAK3,PDCD2,PDE1A,PDE3A,PDPK1,ABCB1,PIK3R1,RETREG1,NLE1,PNMA3,ING3,SEPT4,POU3F4,PPARA,MED1,PPP2R2B,PTPA,PPP3CC,PPP5C,VSTM2L,PRKCG,PRKCZ,MAPK7,MAPK8,MAPK9,PRODH,PTK2,PTN,PTPRZ1,USP47,OXR1,RASGRF2,RET,ROBO1,FBXW7,RPS6KA2,LRRK2,SOX8,KCNIP3,RXRA,S100B,CSRNP3,DRAXIN,SCP2,FNIP1,SELL,SFPQ,SGK1,ITSN1,MYO18A,AMBRA1,ST6GAL1,LIMS2,SIRT2,CPEB4,SMARCA4,SNCB,SNCA,FAIM2,SON,SOX2,SOX10,SOX11,SPP1,UNC5B,CDK19,SRPK2,DIP2A,STXBP1,FGD4,ARHGEF9,MCF2L,TAF9,TCF7,TCF7L2,TRIM2,ARHGEF12,TEK,ATP13A2,DICER1,SIRT1,ZFPM2,ITGB3BP,LEFTY2,ZMAT3,TGFBR3,THRA,TIAM1,NACC2,BHLHB9,TLR4,NR2E1,HEY2,TNFRSF1B,CABIN1,TP53BP2,ZNF346,TRIO,TRPM2,TRPS1,TSC1,TTPA,SGK3,UBC,PDIA2,BCL2L13,MTCH1,VAV1,VAV2,MICAL1,WNT7A,WRN,XRCC4,FMN2,SPHK2,ZBTB16,MEIS3,MAP3K12,MFF,SCG2,CIAPIN1,ITM2C,WNK3,FZD3,DOCK8,RTN4,PAK5,NLRP3" GO: Biological Process GO:2000114 regulation of establishment of cell polarity 3.71E-03 1.00E+00 4.91E-02 4.80E-01 9 19 "SHTN1,KRIT1,WDPCP,PTK2B,RACK1,GSN,BCAS3,KANK1,RICTOR" GO: Biological Process GO:0030835 negative regulation of actin filament depolymerization 3.72E-03 1.00E+00 4.92E-02 4.80E-01 16 44 "ADD1,ADD2,SHROOM2,SPTBN4,DMTN,EPS8,EVL,GSN,SCIN,DBNL,TMOD2,RDX,SPTAN1,SPTB,TMOD1,PLEKHH2" GO: Cellular Component GO:0097458 neuron part 1.20E-99 1.33E-96 1.33E-96 1.01E-95 619 1545 "DPF1,TTYH1,ABAT,SYN3,ACADM,ASIC2,ASIC1,ACHE,ACTN1,ACTN2,ARID1A,GPRIN1,NDRG2,ADCY2,ADCYAP1R1,ADD1,ADD2,ADD3,SLC12A5,ERMN,ADORA1,ADORA2A,UNC5A,ADRB2,NLGN4X,KCTD16,LRRC7,SEMA6A,ALCAM,ALK,SYT13,BEGAIN,DOC2A,AMPH,BIN1,OGT,ANK1,ANK2,ANK3,PPFIA4,PPFIA2,CNIH2,PPFIA1,CNTNAP1,APBA2,APBB1,KCNAB2,APBB2,APC,ALS2,PPFIA3,APP,SHTN1,CPNE5,SHROOM2,MADD,CASK,SPTBN4,ARRB1,ARRB2,CADPS,ASCL1,MARK4,BRINP2,NCOA1,ATP1A1,ATP1A2,ATP1A3,ATP2B1,ATP2B2,ATP6V1G2,ATP6V0A1,KIF1A,BBS2,MPDZ,RGS11,RGS9,HCN2,NRP2,PROM1,BMPR1B,CDK5R1,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,NGB,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,SYT6,CCK,P2RX6,SYNGR3,NEURL1,DGKI,ARHGEF2,SEPT7,CDC42,CDH2,CDH8,DCLK1,DLGAP2,DLGAP1,CBARP,CHRM1,PLEKHB1,CHRM4,SYNPR,CHRNA4,RAB3C,TAOK2,DLGAP3,CPNE6,NRXN3,CLCN3,NRXN1,NRXN2,CLU,CLTC,NGEF,CNGA3,CNN3,CNR1,PICK1,WHRN,SLC25A27,AKAP5,SLC4A7,SLC4A8,MYRIP,ZNF385A,CRHBP,CRMP1,SLC32A1,AATK,SNCAIP,TENM4,FEZ1,CSNK1E,SIPA1L1,RIMS4,CNTNAP2,CST3,SDC3,ERC2,CTNND1,CTNND2,NRSN1,RIMS2,CX3CR1,CYBB,BOC,DOCK4,ARHGAP32,RIPOR2,SNPH,FRMPD4,RIMS3,KCTD8,DBI,DBN1,DCC,DNAJC6,CNIH3,TIAM2,MAGI2,BLOC1S6,SNAP91,SACS,PARD6A,SV2B,SV2A,NTM,DLG2,DLG3,DLG4,GRIN3A,RAB39B,DMD,DNM1,DNM2,SHANK1,CPEB2,SLC12A6,DPP6,DPYSL2,DRD1,ABI1,DRP2,DSCAM,DTNA,DNM1L,USH1C,SEZ6L2,ATL1,EEF1A2,SYT15,EFNA2,ABI2,EIF4G2,COPS4,TNK2,ELAVL4,RGS17,ENO2,EPB41L1,DMTN,RASGRP2,SEZ6,EPHA5,EPHB1,GPHN,STX2,EPS8,CDHR1,ADGRV1,FABP7,ACSL4,PTK2B,TUBB3,TUBB4A,RACK1,PPP1R1B,OLFM1,FGF13,ACTL6B,BAIAP2,CAP2,VTI1B,SYNCRIP,PSD2,SGIP1,SYT3,DCTN2,PDLIM5,NPTN,STAU2,TBR1,BRSK1,GABBR1,GABRA2,GABRA5,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GAD2,JPH4,GAP43,SYT17,DISC1,ATP8A2,INPP5K,CPLX2,CPLX1,DNER,GFRA1,GHR,C1QL1,PPARGC1A,KIRREL3,NTNG2,CRCP,GLRB,GLUL,GNAO1,GNAS,GNG3,GPM6A,GPER1,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,KIF3A,PTPN5,IL1RAPL1,FAM107A,PTGDR2,HRH3,ELOVL5,ACOT7,HMGB1,SCRG1,SYNPO,HNMT,HNRNPK,HPCA,NEGR1,CPT1C,AGFG1,HSP90AA1,HTR2A,HTR5A,ATCAY,ICA1,MYLK2,IGF1,DOCK7,KNDC1,IL6R,IL6ST,BRINP3,SLC6A17,LRRTM1,ITPKA,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNJ10,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,KIF5A,KIF5C,KLC1,STXBP5,L1CAM,LAMA2,LRRC4B,STMN1,SYTL4,PACRG,MAG,ZFYVE27,MAP2,MAP4,MAPT,AQP11,MBP,SYT9,SCAMP5,GIT1,DBNL,BLOC1S2,ADAM22,MT3,MYO5A,MYO6,MYO7A,NAP1L1,NCAM1,NCAM2,NEFM,NEFH,NELL2,NF1,NOS1,NPY,NPTX1,NRCAM,NRGN,HCN1,NTRK2,NUMA1,OCRL,OPA1,OPHN1,OPRL1,P2RX7,P2RY1,PALM,PCDH8,PCDH9,PCSK2,PDE1A,PDE1C,PDE2A,PDE4B,PDE1B,PDPK1,PDYN,PENK,TMOD2,NLGN3,SERPINE2,PIK3R1,EPN1,STRN3,PACSIN1,FAT3,POLG,SH3KBP1,DRAM2,NKAIN4,PPP5C,SKOR1,PRKCG,PRKCZ,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPN13,PTPRN,PTPRN2,PTPRO,PTPRZ1,STRC,QDPR,RAB3A,RAP1GAP,RASGRF1,RDX,CRTAC1,RET,RGS7,RGS10,RGS12,TTLL7,MYH14,ROBO1,KIRREL1,ROBO2,ROM1,TMEM100,LRRK2,SYNDIG1,ATAT1,KCNIP3,WLS,KCNIP1,RXRA,STX1B,S100B,SCN2A,SCN3A,SCN8A,SGK1,ITSN1,PPP1R9A,CPEB3,CNKSR2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,RPH3A,SLC6A1,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SIRT2,SHANK2,LGI3,CPEB4,ARFGAP1,SMARCA4,SMARCC2,SORCS3,SMARCD3,SMARCE1,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,PALLD,PDZD2,NMNAT2,MYCBP2,ERC1,SPTAN1,KIF1B,RAP1GAP2,DDN,NFASC,CLASP2,CLSTN2,SST,SSTR1,SSTR2,EPB41L3,LRRC4,NCDN,MAPK8IP3,STAU1,STX1A,SEPT3,STXBP1,SYT11,ABCC8,VAMP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,COBL,SYT4,SYT5,TAC1,TACR1,ROBO3,EXOC7,CNTN2,ADGRL3,DMXL2,WDR7,PCDHGB1,AZIN2,SYNE1,PUM2,CRTC1,AHCYL2,ATP13A2,DICER1,SIRT1,TIAM1,TNFRSF1B,PARD3,SEZ6L,TPM3,TRPM2,ZMYND8,NTSR2,TMPRSS5,TSC1,TSC2,HEPACAM,CADM1,UCHL1,OSBP2,FLRT2,FLRT1,VGF,RBFOX3,CLIP2,WNT7A,WRN,KLC2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,SLC30A3,MAP3K12,MFF,CADM2,LRP8,SLC38A1,RGMA,GDPD5,STMN4,PCDH15,SLC17A7,KCNAB1,TMEM163,SLC17A6,GOPC,FZD3,RTN4,HNRNPA3,CAMK1G,SNX14,FXR1,IFT88,DPF3,AP3B2,SLC4A10" GO: Cellular Component GO:0045202 synapse 6.04E-92 6.73E-89 3.36E-89 2.55E-88 413 870 "SYN3,ASIC2,ASIC1,ACHE,ACTN1,ACTN2,DSCAML1,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,KCTD16,LRRC7,SPARCL1,SYT13,DOC2A,AMPH,BIN1,LRFN1,ANK1,ANK2,ANK3,PPFIA4,PPFIA2,CNIH2,PPFIA1,PKP4,APBA2,APBB1,KCNAB2,APBB2,APC,ALS2,LRRC4C,BCAS1,PPFIA3,APP,MADD,CASK,ARRB1,RGS20,ARRB2,CADPS,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP6V1G2,ATP6V0A1,ADGRB1,ADGRB3,MPDZ,HCN2,CDK5R1,SYNJ1,MTMR2,BSN,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNB4,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,SYT6,CBLN1,SHISA7,CCK,P2RX6,SYNGR3,NEURL1,DGKI,ARHGEF2,SEPT7,CDH2,CDH8,DCLK1,LGI1,DLGAP2,DLGAP1,CBARP,CHN2,CHRM1,CHRM4,SYNPR,CHRNA4,RAB3C,CHRNB2,DLGAP3,NRXN3,CLCN3,NRXN1,NRXN2,CLTC,HOMER3,CNN3,PICK1,WHRN,CABP1,COL4A5,AKAP5,SLC4A7,MYRIP,NECTIN3,SLC32A1,SNCAIP,SIPA1L1,RIMS4,ERC2,CTNND1,CTNND2,RIMS2,ARHGAP32,SNPH,FRMPD4,HDAC4,RIMS3,KCTD8,DBI,DBN1,DNAJC6,CNIH3,MAGI2,BLOC1S6,SNAP91,SV2B,SV2A,NTM,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM1,DNM2,SHANK1,CPEB2,DPYSL2,DRD1,ABI1,DRP2,DSCAM,DTNA,DTNB,DNM1L,USH1C,SYT15,EFNA2,EGFR,COPS4,RGS17,ENO2,EPB41L1,DMTN,RASGRP2,SEZ6,GPHN,STX2,EPS8,ERBB2,ERBB4,ADGRV1,NRN1,PTK2B,OLFM1,BAIAP2,CAP2,VTI1B,SGIP1,SYT3,NBEA,PDLIM5,NPTN,NSG1,BRSK1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GAP43,SYT17,DISC1,CPLX2,CPLX1,C1QL1,GLRB,GNG3,GPM6A,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KIF3A,IL1RAPL1,HRH3,SYNPO,HNRNPK,HPCA,CPT1C,SHISA6,ATCAY,ICA1,MYLK2,TMEM240,SLC6A17,LRRTM3,LRRTM1,ITGA7,ITPKA,KCNA1,KCNA2,OLFM3,KCNB1,KCNC2,KCND2,KCNH1,KCNJ4,KCNJ10,KCNK1,KCNMA1,KCNN2,KCNN3,STXBP5,L1CAM,LAMA2,LRRC4B,SYTL4,MAP2,MAP4,MAPT,SYT9,MEF2C,SCAMP5,GIT1,DBNL,MT3,MYO5A,MYO6,MYO7A,NEFH,NF1,NOS1,NPY,NRCAM,NRGN,HCN1,NTRK2,OPHN1,P2RX7,P2RY1,PALM,PCDH8,PDE2A,PDE4B,PDPK1,PENK,NLGN3,SERPINE2,EPN1,SDK2,PACSIN1,POLG,SH3KBP1,PPP3CA,PRKCG,MAPK10,NDUFS7,PTCH1,PTN,PTPRN,PTPRN2,PTPRO,PTPRZ1,RAB3A,IQSEC3,PRRT2,RGS10,RGS12,PRIMA1,LRRK2,SYNDIG1,STX1B,LRRTM4,NLGN4Y,ITSN1,PPP1R9A,CPEB3,SHC4,CNKSR2,BCAN,NLGN1,CLSTN1,SLC1A2,SLC1A3,RPH3A,SLC6A9,SLC8A2,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,LGI3,CPEB4,ARFGAP1,SORCS3,IGSF9B,RIMS1,SNAP25,SNCB,SNCA,FAIM2,PDZRN3,PDZD2,NMNAT2,ERC1,DDN,SPART,CLSTN2,EPB41L3,ZC4H2,LRRC4,STX1A,SEPT3,STXBP1,SYT11,ABCC8,VAMP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DNMBP,CNTN2,VWC2,DMXL2,WDR7,SYNE1,PSD3,CRTC1,THBS4,TIAM1,RIMBP2,PRRT1,ZMYND8,RUSC1,CADM1,FRRS1L,FLRT2,WNT7A,TRIM9,ELFN1,ANKS1B,SYNC,SLC30A3,MFF,CADM2,LRP8,PCDH15,SLC17A7,TMEM163,SLC17A6,GOPC,FZD3,RTN4,SSPN,FXR1,NETO2,NETO1" GO: Cellular Component GO:0043005 neuron projection 3.43E-86 3.82E-83 1.27E-83 9.66E-83 498 1194 "TTYH1,ABAT,ACADM,ASIC2,ASIC1,ACHE,ACTN1,ACTN2,GPRIN1,NDRG2,ADCY2,ADCYAP1R1,ADD1,SLC12A5,ERMN,ADORA1,ADORA2A,UNC5A,ADRB2,NLGN4X,LRRC7,SEMA6A,ALCAM,ALK,BEGAIN,DOC2A,AMPH,BIN1,OGT,ANK1,ANK2,ANK3,CNIH2,CNTNAP1,APBB1,KCNAB2,APBB2,APC,ALS2,APP,SHTN1,CPNE5,CASK,SPTBN4,ARRB1,ARRB2,MARK4,BRINP2,NCOA1,ATP1A2,ATP1A3,ATP2B1,ATP2B2,ATP6V0A1,KIF1A,MPDZ,RGS11,HCN2,NRP2,BMPR1B,CDK5R1,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,NGB,CAMK2A,CAMK2B,CAMK2D,CANX,CCK,P2RX6,NEURL1,DGKI,ARHGEF2,SEPT7,CDC42,CDH2,CDH8,DLGAP2,CBARP,CHRM1,CHRM4,SYNPR,CHRNA4,TAOK2,DLGAP3,CPNE6,CLCN3,NRXN1,CLU,CLTC,NGEF,CNGA3,CNN3,CNR1,PICK1,WHRN,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SLC32A1,AATK,TENM4,FEZ1,CSNK1E,SIPA1L1,CNTNAP2,CST3,SDC3,ERC2,CTNND1,CTNND2,NRSN1,RIMS2,CX3CR1,CYBB,BOC,ARHGAP32,SNPH,FRMPD4,DBN1,DCC,CNIH3,TIAM2,MAGI2,BLOC1S6,SNAP91,SACS,PARD6A,SV2B,SV2A,NTM,DLG2,DLG3,DLG4,GRIN3A,RAB39B,DMD,DNM1,DNM2,SHANK1,CPEB2,SLC12A6,DPYSL2,DRD1,ABI1,DRP2,DSCAM,DTNA,ATL1,ABI2,EIF4G2,TNK2,ELAVL4,RGS17,ENO2,RASGRP2,SEZ6,EPHA5,EPHB1,GPHN,EPS8,PTK2B,TUBB3,TUBB4A,RACK1,OLFM1,FGF13,BAIAP2,SYNCRIP,PSD2,SGIP1,DCTN2,PDLIM5,NPTN,STAU2,GABBR1,GABRA2,GABRA5,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GAD2,JPH4,GAP43,DISC1,INPP5K,CPLX2,CPLX1,DNER,GFRA1,C1QL1,PPARGC1A,KIRREL3,NTNG2,CRCP,GLRB,GLUL,GNAO1,GNAS,GNG3,GPM6A,GPER1,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KIF3A,PTPN5,IL1RAPL1,FAM107A,PTGDR2,HRH3,ELOVL5,ACOT7,HMGB1,SCRG1,SYNPO,HNMT,HNRNPK,HPCA,NEGR1,CPT1C,HSP90AA1,HTR2A,HTR5A,ATCAY,ICA1,MYLK2,DOCK7,KNDC1,IL6ST,BRINP3,LRRTM1,ITPKA,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN2,KCNN3,KCNQ2,KCNQ3,KIF5A,KIF5C,KLC1,L1CAM,LAMA2,LRRC4B,STMN1,PACRG,MAG,ZFYVE27,MAP2,MAP4,MAPT,AQP11,MBP,GIT1,DBNL,BLOC1S2,ADAM22,MT3,MYO5A,MYO6,NAP1L1,NCAM1,NCAM2,NEFM,NEFH,NELL2,NF1,NOS1,NPY,NPTX1,NRCAM,NRGN,HCN1,NTRK2,NUMA1,OPA1,OPHN1,OPRL1,P2RY1,PALM,PCDH8,PCDH9,PCSK2,PDE2A,PDE4B,PDYN,PENK,TMOD2,NLGN3,PIK3R1,EPN1,STRN3,PACSIN1,FAT3,POLG,SH3KBP1,PPP5C,SKOR1,PRKCG,PRKCZ,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPN13,PTPRN,PTPRN2,PTPRO,PTPRZ1,QDPR,RAB3A,RAP1GAP,RASGRF1,CRTAC1,RET,RGS7,RGS10,RGS12,TTLL7,MYH14,ROBO1,KIRREL1,ROBO2,LRRK2,SYNDIG1,ATAT1,KCNIP3,WLS,KCNIP1,RXRA,SCN2A,SCN3A,SCN8A,SGK1,ITSN1,PPP1R9A,CPEB3,CNKSR2,BCAN,NLGN1,SLC1A2,SLC1A3,RPH3A,SLC6A1,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SIRT2,SHANK2,LGI3,CPEB4,IGSF9B,SNAP25,SNCB,SNCA,PALLD,PDZD2,MYCBP2,SPTAN1,KIF1B,RAP1GAP2,DDN,NFASC,CLASP2,SSTR1,SSTR2,EPB41L3,LRRC4,NCDN,MAPK8IP3,STAU1,STX1A,SEPT3,STXBP1,SYT11,VAMP1,SYN1,ARC,SYN2,SYP,SYT1,COBL,SYT4,SYT5,TAC1,TACR1,ROBO3,EXOC7,CNTN2,ADGRL3,PCDHGB1,AZIN2,SYNE1,PUM2,CRTC1,AHCYL2,ATP13A2,DICER1,SIRT1,TIAM1,TNFRSF1B,PARD3,TPM3,TRPM2,ZMYND8,NTSR2,TSC1,TSC2,HEPACAM,CADM1,UCHL1,OSBP2,FLRT2,FLRT1,VGF,CLIP2,WRN,KLC2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,SLC30A3,MAP3K12,CADM2,LRP8,SLC38A1,RGMA,GDPD5,STMN4,SLC17A7,KCNAB1,SLC17A6,GOPC,FZD3,RTN4,HNRNPA3,CAMK1G,SNX14,FXR1,AP3B2,SLC4A10" GO: Cellular Component GO:0044456 synapse part 3.50E-78 3.89E-75 9.73E-76 7.39E-75 342 708 "SYN3,ASIC2,ASIC1,ACHE,ACTN1,ACTN2,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,KCTD16,LRRC7,SYT13,DOC2A,AMPH,BIN1,LRFN1,ANK1,ANK2,ANK3,PPFIA4,PPFIA2,CNIH2,PPFIA1,PKP4,APBA2,APBB1,KCNAB2,ALS2,LRRC4C,BCAS1,PPFIA3,APP,MADD,CASK,ARRB1,RGS20,ARRB2,CADPS,ATP1A1,ATP1A2,ATP1A3,ATP2B1,ATP6V1G2,ATP6V0A1,ADGRB1,ADGRB3,MPDZ,CDK5R1,SYNJ1,MTMR2,BSN,BAIAP3,CACNA1A,CACNA1B,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CANX,SYT6,CBLN1,CCK,P2RX6,SYNGR3,NEURL1,DGKI,ARHGEF2,CDH2,CDH8,DCLK1,DLGAP2,DLGAP1,CBARP,CHRM1,CHRM4,SYNPR,CHRNA4,RAB3C,CHRNB2,DLGAP3,NRXN3,CLCN3,NRXN1,NRXN2,CLTC,HOMER3,CNN3,PICK1,CABP1,AKAP5,NECTIN3,SLC32A1,SNCAIP,SIPA1L1,RIMS4,ERC2,CTNND1,CTNND2,RIMS2,ARHGAP32,SNPH,FRMPD4,RIMS3,KCTD8,DBI,DBN1,DNAJC6,CNIH3,MAGI2,BLOC1S6,SNAP91,SV2B,SV2A,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM1,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DRP2,DNM1L,SYT15,COPS4,ENO2,EPB41L1,DMTN,SEZ6,GPHN,STX2,EPS8,ERBB2,ERBB4,PTK2B,OLFM1,BAIAP2,CAP2,VTI1B,SGIP1,SYT3,NBEA,PDLIM5,NPTN,NSG1,BRSK1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GAP43,SYT17,DISC1,CPLX2,CPLX1,C1QL1,GLRB,GNG3,GPM6A,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IL1RAPL1,HRH3,SYNPO,HNRNPK,HPCA,ICA1,MYLK2,TMEM240,SLC6A17,LRRTM3,LRRTM1,ITPKA,KCNA1,KCNA2,KCNB1,KCNC2,KCND2,KCNH1,KCNJ4,KCNJ10,KCNMA1,KCNN2,STXBP5,L1CAM,LAMA2,LRRC4B,SYTL4,MAP2,MAP4,MAPT,SYT9,MEF2C,SCAMP5,DBNL,MT3,MYO5A,NEFH,NF1,NOS1,NPY,NRGN,NTRK2,OPHN1,P2RX7,P2RY1,PALM,PCDH8,PDE2A,PDE4B,PDPK1,NLGN3,EPN1,PACSIN1,POLG,PPP3CA,PRKCG,MAPK10,NDUFS7,PTCH1,PTPRN,PTPRN2,PTPRO,PTPRZ1,RAB3A,IQSEC3,RGS10,LRRK2,SYNDIG1,STX1B,LRRTM4,NLGN4Y,ITSN1,PPP1R9A,SHC4,CNKSR2,NLGN1,CLSTN1,SLC1A2,SLC1A3,RPH3A,SLC6A9,SLC8A2,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,LGI3,CPEB4,ARFGAP1,SORCS3,RIMS1,SNAP25,SNCB,SNCA,FAIM2,PDZD2,ERC1,DDN,CLSTN2,EPB41L3,ZC4H2,LRRC4,STX1A,SEPT3,STXBP1,SYT11,ABCC8,VAMP1,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,SYNE1,PSD3,TIAM1,ZMYND8,RUSC1,CADM1,WNT7A,TRIM9,ANKS1B,SLC30A3,MFF,LRP8,SLC17A7,TMEM163,SLC17A6,GOPC,FZD3,RTN4,SSPN,FXR1,NETO2,NETO1" GO: Cellular Component GO:0036477 somatodendritic compartment 3.13E-65 3.48E-62 6.97E-63 5.29E-62 368 867 "ASIC2,ASIC1,ACHE,ACTN1,ACTN2,ADCY2,ADD1,SLC12A5,ERMN,ADORA1,ADORA2A,UNC5A,ADRB2,NLGN4X,LRRC7,ALCAM,BEGAIN,OGT,ANK3,CNIH2,APBB1,APC,ALS2,APP,SHTN1,CPNE5,SHROOM2,CASK,SPTBN4,ARRB1,ARRB2,ASCL1,BRINP2,ATP1A2,ATP1A3,ATP2B1,ATP2B2,KIF1A,MPDZ,RGS11,HCN2,BMPR1B,CDK5R1,ARHGEF7,MTMR2,SGCE,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALB1,KALRN,HAP1,PTBP2,NGB,CAMK2A,CAMK2B,CAMK2D,CANX,CCK,P2RX6,NEURL1,DGKI,ARHGEF2,CDC42,CDH2,DLGAP2,CHRM1,CHRM4,CHRNA4,TAOK2,DLGAP3,CPNE6,NRXN1,CLU,CNGA3,CNN3,PICK1,WHRN,SLC25A27,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SLC32A1,SNCAIP,FEZ1,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CTNND1,CTNND2,NRSN1,CX3CR1,CYBB,BOC,ARHGAP32,SNPH,FRMPD4,DBN1,CNIH3,MAGI2,SACS,PARD6A,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DPP6,DPYSL2,DRD1,DRP2,SEZ6L2,EEF1A2,EFNA2,ABI2,TNK2,ELAVL4,ENO2,SEZ6,EPHA5,EPHB1,GPHN,FABP7,ACSL4,PTK2B,TUBB3,TUBB4A,RACK1,PPP1R1B,OLFM1,FGF13,BAIAP2,VTI1B,SYNCRIP,PSD2,NPTN,STAU2,GABBR1,GABRA2,GABRA5,CHL1,GABRB1,JPH4,CPLX2,CPLX1,DNER,GFRA1,GHR,PPARGC1A,KIRREL3,CRCP,GLRB,GLUL,GNAO1,GNAS,GNG3,GPM6A,GPER1,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,KIF3A,PTPN5,IL1RAPL1,ELOVL5,SYNPO,HNRNPK,HPCA,NEGR1,CPT1C,AGFG1,HSP90AA1,HTR2A,HTR5A,ATCAY,ICA1,MYLK2,IGF1,KNDC1,IL6R,IL6ST,BRINP3,ITPKA,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,KLC1,L1CAM,LAMA2,ZFYVE27,MAP2,MAPT,AQP11,MBP,DBNL,MT3,MYO5A,MYO6,NCAM1,NEFH,NELL2,NF1,NOS1,NPY,NRGN,HCN1,NTRK2,NUMA1,OPA1,OPHN1,P2RX7,P2RY1,PALM,PCDH8,PCSK2,PDE1A,PDE1C,PDE2A,PDE4B,PDE1B,PDPK1,PDYN,PENK,NLGN3,SERPINE2,STRN3,FAT3,PPP5C,SKOR1,PRKCG,PRKCZ,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTCH1,PTPRN,PTPRO,PTPRZ1,RAP1GAP,RASGRF1,RET,RGS7,RGS10,RGS12,TTLL7,ROBO1,KIRREL1,TMEM100,LRRK2,SYNDIG1,KCNIP3,WLS,KCNIP1,S100B,SCN3A,SCN8A,PPP1R9A,CPEB3,CNKSR2,BCAN,NLGN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,SLC8A3,SIRT2,SHANK2,CPEB4,IGSF9B,SNAP25,SNCB,PALLD,DDN,SST,LRRC4,NCDN,MAPK8IP3,STAU1,SYT11,SYN1,ARC,COBL,SYT5,TAC1,TACR1,CNTN2,AZIN2,SYNE1,PUM2,CRTC1,ATP13A2,DICER1,TIAM1,TNFRSF1B,PARD3,SEZ6L,TRPM2,ZMYND8,NTSR2,TMPRSS5,TSC2,CADM1,UCHL1,OSBP2,FLRT1,VGF,RBFOX3,CLIP2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,CADM2,LRP8,GDPD5,KCNAB1,GOPC,FZD3,RTN4,SNX14,FXR1,SLC4A10" GO: Cellular Component GO:0044463 cell projection part 2.69E-58 2.99E-55 4.99E-56 3.79E-55 429 1139 "TTYH1,SYN3,ASIC2,ASIC1,ACTN1,ACTN2,GPRIN1,NDRG2,ADCY6,ADD1,ADD2,ADD3,SLC12A5,ERMN,FZD9,ADORA1,ADORA2A,UNC5A,ADRB2,AP2A1,WDR35,CC2D2A,AK2,LRRC7,CEP126,AMPH,BIN1,ANK1,ANK3,FGD2,CNIH2,CNTNAP1,APBB1,KCNAB2,APBB2,APC,EPB41L5,ALS2,APP,SHTN1,AQP4,CASK,SPTBN4,ARRB1,ARRB2,DNAH17,MARK4,DYNLL1,ATP1A1,ATP1A2,ATP1A3,ATP2B1,ATP6V0A1,KIF1A,BBS2,RGS11,RGS9,HCN2,PROM1,CDK5R1,SYNJ1,SYNJ2,ARHGEF7,MTMR2,SGCE,BSN,CA4,CACNA1B,CACNA1D,CALB1,CALB2,CALM1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,CCK,P2RX6,SCARB1,ENTPD2,NEURL1,DGKI,ARHGEF2,SEPT7,CDH8,DCLK1,DLGAP1,CBARP,CHRM1,CHRM4,DLGAP3,RAB28,CLCN3,NRXN1,CLU,CLTB,CLTC,NGEF,CCDC151,CNGA3,CNN3,CNR1,PICK1,WHRN,AKAP5,RTTN,CRHBP,SLC32A1,AATK,CSNK1E,OSBPL3,SIPA1L1,CNTNAP2,ERC2,ARHGEF4,CTNND1,NRSN1,BOC,ARHGAP32,RIPOR2,FRMPD4,KIAA0586,AIF1L,DNAL1,DBN1,DCC,DNAJC6,CNIH3,TIAM2,BLOC1S6,SNAP91,PARD6A,SV2B,SV2A,KIF19,DLG2,DLG3,DLG4,DMD,DNM1,DNAH9,DNM2,SHANK1,DPYSL2,DRD1,ABI1,DSCAM,WDPCP,PLEKHA1,TNK2,ELAVL4,PLEKHO1,MFSD10,EPB41L1,DMTN,RASGRP2,SEZ6,EPHB1,EPS8,CDHR1,APC2,ADGRV1,SH3YL1,PTK2B,TUBB4A,DLC1,OLFM1,FGF13,BAIAP2,FGR,CAP2,SYNCRIP,SGIP1,DCTN2,AKAP3,TMEM107,AK8,STAU2,GABBR1,GABRA2,GABRB3,GABRG2,GAD1,JPH4,NCKAP1,GAP43,DISC1,SEPT9,INPP5K,CPLX2,CPLX1,KIRREL3,GLI2,GLUL,GNG3,FERMT2,GPM6A,MCHR1,GPER1,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,NR3C1,GRM1,GRM3,GRM5,GRM7,KIF3A,PTPN5,BVES,RABL2A,PACSIN2,SCRG1,SYNPO,HNRNPK,HPCA,CFAP126,HSP90AA1,HTR2A,MYLK2,DOCK7,LRRTM1,ITGAV,ITPKA,KCNA1,KCNA2,KCNA6,KCNB1,KCNC1,KCNC2,KCND2,KCNH1,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN2,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,KLC1,L1CAM,LAMA2,PACRG,MAG,ZFYVE27,MAP2,MAP4,MAPT,MBP,POC1B,BLOC1S2,MT3,MTTP,MYO5A,MYO6,MYO7A,NCAM1,NEFH,NOS1,NPY,SLC11A2,NRCAM,NRGN,HCN1,NTRK2,ODF2,OPA1,OPHN1,P2RY1,SNTG1,PALM,PCDH9,PDE4A,PDE4B,PDPK1,PDYN,PENK,TMOD2,ABCB1,PKD1,EPN1,SPATA6,SEPT4,PACSIN1,POLG,PPP5C,PRKACB,CEP41,PRKAR1B,PRKCB,PRKCG,PRKCZ,MAPK8,MAPK10,HYDIN,PRPH,PTCH1,PTH1R,PTPRN,PTPRN2,PTPRO,PTPRZ1,STRC,TMEM231,RAB3A,CCDC40,ATG16L1,RASGRF1,CRTAC1,RGS7,RGS10,KIF7,MYH14,ROBO1,KIRREL1,ROBO2,ROM1,LRRK2,SYNDIG1,KCNIP3,WLS,SCN2A,SCN8A,ITSN1,PPP1R9A,FERMT1,AMBRA1,CNKSR2,NLGN1,DZIP1,CLSTN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,SLC8A3,SIRT2,SHANK2,SLCO1A2,ARFGAP1,SORCS3,IFT122,SNAP25,SNCB,SNCA,PALLD,SPATA7,CLUAP1,ENKUR,SPTAN1,KIF1B,DDN,NFASC,CLASP2,CLSTN2,EPB41L3,LRRC4,MAPK8IP3,TTBK2,KANK1,STXBP1,SYT11,SYNE2,VAMP1,SYN1,ARC,SYN2,SYP,SYT1,COBL,EXOC7,CNTN2,WWC1,RPGRIP1L,PCDHGB1,SYNE1,DNAH7,DICER1,SIRT1,GPR161,HHIP,TIAM1,TNFRSF1B,PARD3,TPM1,TPM3,ZMYND8,NTSR2,TSC1,TSC2,CADM1,UCHL1,FLRT1,CLIP2,KLC2,NDRG4,TMEM237,ANKS1B,LAMP5,MAP3K12,DNALI1,GDPD5,STMN4,KCNAB1,SLC17A6,DNAH10,FZD3,RTN4,FXR1,IFT88,AP3B2,SPATA13" GO: Cellular Component GO:0098794 postsynapse 2.08E-53 2.32E-50 3.31E-51 2.51E-50 223 449 "SYN3,ASIC2,ASIC1,ACHE,ACTN1,ACTN2,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,LRFN2,ADRB2,NLGN4X,KCTD16,LRRC7,LRFN1,ANK1,ANK2,ANK3,CNIH2,PKP4,APBB1,KCNAB2,ALS2,LRRC4C,BCAS1,APP,ARRB1,RGS20,ARRB2,ATP1A1,ATP1A2,ATP1A3,ADGRB1,ADGRB3,MPDZ,CDK5R1,MTMR2,BSN,KALRN,CAMK2A,CAMK2B,CAMK2G,CANX,CBLN1,P2RX6,NEURL1,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,CHRM1,CHRM4,CHRNA4,CHRNB2,DLGAP3,HOMER3,CNN3,PICK1,CABP1,AKAP5,NECTIN3,SIPA1L1,ERC2,CTNND1,CTNND2,ARHGAP32,FRMPD4,KCTD8,DBN1,DNAJC6,CNIH3,MAGI2,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM2,SHANK1,DRD1,ABI1,DRP2,EPB41L1,DMTN,SEZ6,GPHN,EPS8,ERBB2,ERBB4,PTK2B,BAIAP2,CAP2,NBEA,PDLIM5,NPTN,NSG1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAP43,DISC1,GLRB,GNG3,GPM6A,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM3,GRM5,GRM7,IL1RAPL1,SYNPO,HNRNPK,HPCA,MYLK2,LRRTM3,LRRTM1,ITPKA,KCNB1,KCNC2,KCND2,KCNJ4,KCNMA1,KCNN2,LAMA2,MAP2,MAP4,MAPT,MEF2C,DBNL,MT3,NEFH,NF1,NOS1,NRGN,NTRK2,OPHN1,P2RY1,PALM,PCDH8,PDE4B,PDPK1,NLGN3,PPP3CA,PRKCG,MAPK10,PTCH1,PTPRO,PTPRZ1,IQSEC3,RGS10,LRRK2,SYNDIG1,LRRTM4,NLGN4Y,PPP1R9A,SHC4,CNKSR2,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,CPEB4,ARFGAP1,SORCS3,RIMS1,SNCA,FAIM2,PDZD2,CLSTN2,EPB41L3,ZC4H2,LRRC4,SYT11,SYN1,ARC,SYN2,SYNE1,PSD3,TIAM1,ZMYND8,RUSC1,ANKS1B,LRP8,SLC17A7,GOPC,RTN4,SSPN,FXR1,NETO2,NETO1" GO: Cellular Component GO:0030425 dendrite 1.83E-52 2.04E-49 2.55E-50 1.93E-49 265 590 "ASIC2,ASIC1,ACHE,ACTN1,ACTN2,ADCY2,ADD1,SLC12A5,ADORA1,ADORA2A,ADRB2,NLGN4X,LRRC7,ALCAM,BEGAIN,ANK3,CNIH2,APBB1,APC,ALS2,APP,CASK,ARRB1,ARRB2,BRINP2,ATP1A2,ATP1A3,ATP2B2,MPDZ,RGS11,HCN2,BMPR1B,CDK5R1,MTMR2,SGCE,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CALB1,HAP1,CAMK2A,CAMK2B,CANX,CCK,P2RX6,NEURL1,DGKI,ARHGEF2,CDH2,DLGAP2,CHRM1,CHRNA4,TAOK2,DLGAP3,CPNE6,CLU,CNGA3,CNN3,PICK1,WHRN,AKAP5,ZNF385A,CRHBP,CRMP1,SLC32A1,FEZ1,SIPA1L1,CNTNAP2,CTNND1,CTNND2,CYBB,ARHGAP32,FRMPD4,DBN1,CNIH3,MAGI2,SACS,DLG2,DLG3,DLG4,SHANK1,DPYSL2,DRD1,DRP2,ABI2,TNK2,ELAVL4,SEZ6,EPHA5,EPHB1,GPHN,PTK2B,TUBB3,RACK1,FGF13,BAIAP2,SYNCRIP,PSD2,NPTN,STAU2,GABBR1,GABRA2,GABRA5,CHL1,GABRB1,JPH4,CPLX2,CPLX1,DNER,PPARGC1A,KIRREL3,CRCP,GLRB,GNAO1,GNAS,GNG3,GPM6A,GPER1,GRK4,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,PTPN5,IL1RAPL1,ELOVL5,SYNPO,HNRNPK,HPCA,NEGR1,CPT1C,HTR2A,HTR5A,ATCAY,ICA1,MYLK2,KNDC1,IL6ST,BRINP3,ITPKA,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNK1,KCNMA1,KCNN2,KCNQ3,L1CAM,LAMA2,ZFYVE27,MAP2,MAPT,AQP11,DBNL,MT3,NELL2,NF1,NOS1,NRGN,HCN1,NTRK2,NUMA1,OPA1,OPHN1,P2RY1,PALM,PCDH8,PCSK2,PDE2A,PDE4B,PDYN,PENK,NLGN3,STRN3,FAT3,PPP5C,SKOR1,PRKCG,MAPK8,RELN,PTCH1,PTPRO,PTPRZ1,RAP1GAP,RASGRF1,RET,RGS7,RGS10,RGS12,TTLL7,KIRREL1,LRRK2,SYNDIG1,KCNIP3,WLS,KCNIP1,SCN8A,PPP1R9A,CPEB3,BCAN,NLGN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,SLC8A3,SHANK2,CPEB4,IGSF9B,DDN,LRRC4,NCDN,MAPK8IP3,STAU1,SYT11,SYN1,ARC,COBL,TACR1,AZIN2,SYNE1,PUM2,CRTC1,DICER1,TIAM1,ZMYND8,NTSR2,TSC2,CADM1,OSBP2,CLIP2,TRIM9,ELFN1,DPYSL5,ANKS1B,LAMP5,LRP8,KCNAB1,GOPC,FZD3,SNX14,FXR1,SLC4A10" GO: Cellular Component GO:0030424 axon 5.11E-50 5.69E-47 6.32E-48 4.80E-47 254 567 "TTYH1,ACADM,ACHE,ERMN,ADORA1,ADORA2A,ADRB2,LRRC7,SEMA6A,ALCAM,ALK,AMPH,BIN1,ANK1,ANK3,CNTNAP1,APBB1,KCNAB2,APC,ALS2,APP,SHTN1,SPTBN4,ATP1A3,ATP6V0A1,KIF1A,HCN2,NRP2,CDK5R1,DST,SYNJ1,SYNJ2,MTMR2,BSN,CACNA1B,CALB1,CALB2,HAP1,CAMK2A,CAMK2D,CANX,CCK,DGKI,SEPT7,CDH8,CHRM1,CHRM4,CPNE6,CLCN3,NRXN1,CLTC,CNR1,WHRN,CRHBP,SLC32A1,AATK,FEZ1,CNTNAP2,CST3,SDC3,ERC2,BOC,DBN1,DCC,BLOC1S6,SNAP91,SACS,PARD6A,SV2B,SV2A,NTM,DLG2,DLG4,DNM1,SLC12A6,DPYSL2,DRD1,DSCAM,DTNA,ATL1,EIF4G2,TNK2,EPHA5,EPHB1,PTK2B,TUBB3,TUBB4A,OLFM1,FGF13,SGIP1,STAU2,GABBR1,GABRA2,GABRB3,GABRG2,GAD1,GAD2,GAP43,DISC1,CPLX2,CPLX1,GFRA1,C1QL1,KIRREL3,NTNG2,CRCP,GLUL,GPM6A,GPER1,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM1,GRM2,GRM3,GRM7,KIF3A,PTPN5,IL1RAPL1,SYNPO,HNRNPK,HPCA,CPT1C,HTR2A,ATCAY,MYLK2,DOCK7,LRRTM1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCNH1,KCNJ11,KCNK2,KCNMA1,KCNQ2,KCNQ3,KIF5A,KLC1,L1CAM,LRRC4B,MAG,ZFYVE27,MAPT,MBP,BLOC1S2,ADAM22,MT3,MYO5A,MYO6,NCAM1,NCAM2,NEFM,NEFH,NF1,NPY,NRCAM,NRGN,HCN1,NTRK2,OPA1,OPHN1,PALM,PDE2A,PDYN,PENK,EPN1,PACSIN1,POLG,PRKCZ,MAPK8,PRPH,RELN,PTCH1,PTPRN,PTPRN2,PTPRO,PTPRZ1,RAB3A,RAP1GAP,RET,RGS10,MYH14,ROBO1,ROBO2,LRRK2,ATAT1,KCNIP3,RXRA,SCN2A,SCN3A,SCN8A,ITSN1,SLC1A2,SLC6A1,SIRT2,SNAP25,SNCB,SNCA,PALLD,MYCBP2,SPTAN1,KIF1B,NFASC,CLASP2,EPB41L3,NCDN,MAPK8IP3,STXBP1,SYT11,VAMP1,SYN1,SYN2,SYP,SYT1,COBL,TAC1,ROBO3,CNTN2,ADGRL3,AZIN2,DICER1,SIRT1,TIAM1,TNFRSF1B,PARD3,HEPACAM,CADM1,UCHL1,MAP3K12,CADM2,LRP8,SLC38A1,GDPD5,STMN4,SLC17A7,KCNAB1,SLC17A6,FZD3,FXR1,AP3B2" GO: Cellular Component GO:0043025 neuronal cell body 7.40E-46 8.23E-43 8.23E-44 6.25E-43 261 616 "ASIC2,ACHE,SLC12A5,ERMN,ADORA1,ADORA2A,UNC5A,ADRB2,ALCAM,BEGAIN,OGT,APBB1,APC,ALS2,SHTN1,CPNE5,SHROOM2,SPTBN4,ASCL1,BRINP2,ATP2B1,ATP2B2,KIF1A,HCN2,BMPR1B,CDK5R1,ARHGEF7,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALB1,KALRN,PTBP2,NGB,CAMK2A,CAMK2B,CAMK2D,CANX,CCK,P2RX6,NEURL1,DGKI,ARHGEF2,CDC42,CHRM4,CHRNA4,DLGAP3,CPNE6,NRXN1,CNGA3,CNN3,WHRN,SLC25A27,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SNCAIP,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CTNND2,NRSN1,CX3CR1,CYBB,BOC,SNPH,DBN1,PARD6A,DLG2,DLG3,GRIN3A,DPP6,DPYSL2,DRD1,DRP2,SEZ6L2,EEF1A2,EFNA2,TNK2,ELAVL4,ENO2,SEZ6,EPHA5,GPHN,FABP7,ACSL4,PTK2B,TUBB3,TUBB4A,RACK1,PPP1R1B,OLFM1,BAIAP2,VTI1B,SYNCRIP,PSD2,STAU2,GABBR1,GABRA2,GABRA5,CPLX2,CPLX1,DNER,GFRA1,GHR,PPARGC1A,CRCP,GLUL,GNAS,GPM6A,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM1,GRM7,GRM8,CIT,KIF3A,PTPN5,ELOVL5,SYNPO,HPCA,NEGR1,AGFG1,HSP90AA1,HTR2A,HTR5A,MYLK2,IGF1,KNDC1,IL6R,IL6ST,BRINP3,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,KLC1,L1CAM,MAP2,MBP,MYO5A,MYO6,NCAM1,NEFH,NELL2,NPY,NRGN,HCN1,NTRK2,NUMA1,P2RX7,PCSK2,PDE1A,PDE1C,PDE1B,PDPK1,PDYN,PENK,NLGN3,SERPINE2,STRN3,PPP5C,SKOR1,PRKCZ,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTPRN,PTPRZ1,RAP1GAP,RASGRF1,RET,RGS10,RGS12,TTLL7,ROBO1,TMEM100,LRRK2,KCNIP1,S100B,SCN3A,SCN8A,PPP1R9A,CNKSR2,SLC1A3,SLC8A2,SLC8A3,SIRT2,SHANK2,IGSF9B,SNAP25,SNCB,PALLD,DDN,SST,NCDN,STAU1,COBL,SYT5,TAC1,CNTN2,AZIN2,PUM2,CRTC1,ATP13A2,TIAM1,TNFRSF1B,PARD3,SEZ6L,TRPM2,NTSR2,TMPRSS5,TSC2,UCHL1,FLRT1,VGF,RBFOX3,DPYSL5,CADM2,LRP8,GDPD5,KCNAB1,FZD3,RTN4,SLC4A10" GO: Cellular Component GO:0044297 cell body 3.63E-44 4.04E-41 3.67E-42 2.79E-41 279 691 "ASIC2,ACHE,SLC12A5,ERMN,ADORA1,ADORA2A,UNC5A,ADRB2,ALCAM,ALK,BEGAIN,OGT,APBB1,APC,ALS2,SHTN1,CPNE5,SHROOM2,SPTBN4,ASCL1,BRINP2,ATP2B1,ATP2B2,KIF1A,HCN2,BMPR1B,CDK5R1,ARHGEF7,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALB1,KALRN,PTBP2,NGB,CAMK2A,CAMK2B,CAMK2D,CANX,CCK,P2RX6,ENTPD2,NEURL1,DGKI,ARHGEF2,SEPT7,CDC42,CHRM4,CHRNA4,DLGAP3,CPNE6,NRXN1,CNGA3,CNN3,WHRN,SLC25A27,AKAP5,SLC4A8,ZNF385A,CRHBP,CRMP1,SNCAIP,CSNK1E,SIPA1L1,CNTNAP2,CST3,ERC2,CTNND2,NRSN1,CX3CR1,CYBB,BOC,SNPH,DBN1,PARD6A,DLG2,DLG3,GRIN3A,DPP6,DPYSL2,DRD1,DRP2,SEZ6L2,EEF1A2,EFNA2,TNK2,ELAVL4,ENO2,SEZ6,EPHA5,GPHN,FABP7,ACSL4,PTK2B,TUBB3,TUBB4A,RACK1,PPP1R1B,OLFM1,BAIAP2,VTI1B,SYNCRIP,PSD2,STAU2,GABBR1,GABRA2,GABRA5,DISC1,CPLX2,CPLX1,DNER,GFAP,GFRA1,GHR,PPARGC1A,CRCP,GLUL,GNAO1,GNAS,GNG3,GPM6A,GRK4,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM1,GRM7,GRM8,CIT,KIF3A,PTPN5,ELOVL5,ACOT7,SYNPO,HPCA,NEGR1,AGFG1,HSPA1L,HSP90AA1,HTR2A,HTR5A,MYLK2,IGF1,KNDC1,IL6R,IL6ST,BRINP3,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ3,KIF5A,KLC1,L1CAM,PACRG,MAP2,MAPT,MBP,MYO5A,MYO6,NCAM1,NEFH,NELL2,NPY,NRGN,HCN1,NTRK2,NUMA1,P2RX7,P2RY1,PCSK2,PDE1A,PDE1C,PDE1B,PDPK1,PDYN,PENK,NLGN3,SERPINE2,STRN3,PPP5C,SKOR1,PRKCZ,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,PTPN13,PTPRN,PTPRZ1,RAP1GAP,RASGRF1,RET,RGS10,RGS12,TTLL7,RLBP1,ROBO1,RPE65,TMEM100,LRRK2,SYNDIG1,KCNIP1,S100B,SCN3A,SCN8A,PPP1R9A,CNKSR2,SLC1A3,SLC8A2,SLC8A3,SIRT2,SHANK2,IGSF9B,SNAP25,SNCB,PALLD,USP33,DDN,SST,NCDN,STAU1,COBL,SYT5,TAC1,TACR1,CNTN2,AZIN2,PUM2,CRTC1,ATP13A2,TIAM1,TNFRSF1B,PARD3,SEZ6L,TRPM2,NTSR2,TMPRSS5,TSC2,UCHL1,FLRT1,VGF,RBFOX3,DPYSL5,CADM2,LRP8,GDPD5,KCNAB1,FZD3,RTN4,SLC4A10" GO: Cellular Component GO:0060076 excitatory synapse 4.43E-44 4.93E-41 4.11E-42 3.12E-41 144 252 "SYN3,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,NLGN4X,LRRC7,LRFN1,CNIH2,PKP4,KCNAB2,ALS2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,CDK5R1,MTMR2,BSN,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,NEURL1,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,CHRM1,CHRM4,DLGAP3,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,CTNND2,ARHGAP32,DBN1,DNAJC6,MAGI2,SNAP91,NTM,DLG2,DLG3,DLG4,GRIN3A,DNM2,SHANK1,ABI1,DRP2,EPB41L1,DMTN,EPS8,ERBB4,PTK2B,BAIAP2,CAP2,PDLIM5,NPTN,FYN,GAP43,DISC1,GNG3,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,NR3C1,GRM1,GRM3,GRM5,SYNPO,HNRNPK,MYLK2,LRRTM1,KCND2,MAP2,MAP4,MAPT,DBNL,MT3,NEFH,NF1,NOS1,NRGN,NTRK2,P2RY1,PALM,PDE4B,PDPK1,NLGN3,PRKCG,MAPK10,PTCH1,SYNDIG1,STX1B,NLGN4Y,PPP1R9A,CNKSR2,NLGN1,CLSTN1,SHANK2,CPEB4,ARFGAP1,SORCS3,RIMS1,PDZD2,CLSTN2,EPB41L3,LRRC4,SYT11,SYN1,ARC,SYN2,SYP,SYT1,PSD3,RUSC1,ELFN1,ANKS1B,LRP8,SLC17A7,SLC17A6,GOPC,RTN4,NETO2,NETO1" GO: Cellular Component GO:0099572 postsynaptic specialization 5.30E-41 5.89E-38 4.21E-39 3.20E-38 133 232 "SYN3,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,NLGN4X,LRRC7,LRFN1,CNIH2,PKP4,KCNAB2,ALS2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,CDK5R1,MTMR2,BSN,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,NEURL1,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,CHRM1,CHRM4,DLGAP3,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,CTNND2,ARHGAP32,DBN1,DNAJC6,MAGI2,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DNM2,SHANK1,ABI1,DRP2,EPB41L1,DMTN,EPS8,ERBB4,PTK2B,BAIAP2,CAP2,PDLIM5,NPTN,FYN,GAP43,DISC1,GNG3,GPER1,PCLO,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,NR3C1,GRM1,GRM3,GRM5,SYNPO,HNRNPK,MYLK2,KCND2,MAP2,MAP4,MAPT,DBNL,MT3,NEFH,NF1,NOS1,NRGN,NTRK2,P2RY1,PALM,PDE4B,PDPK1,PRKCG,MAPK10,PTCH1,SYNDIG1,NLGN4Y,PPP1R9A,CNKSR2,NLGN1,CLSTN1,SHANK2,CPEB4,ARFGAP1,SORCS3,RIMS1,PDZD2,CLSTN2,EPB41L3,SYT11,SYN1,ARC,SYN2,PSD3,RUSC1,ANKS1B,LRP8,GOPC,RTN4,NETO2,NETO1" GO: Cellular Component GO:0014069 postsynaptic density 5.30E-41 5.89E-38 4.21E-39 3.20E-38 133 232 "SYN3,ADD1,ADD2,ADD3,AXIN2,ADORA1,ADORA2A,NLGN4X,LRRC7,LRFN1,CNIH2,PKP4,KCNAB2,ALS2,BCAS1,ARRB1,RGS20,ARRB2,ATP1A1,ADGRB1,MPDZ,CDK5R1,MTMR2,BSN,KALRN,CAMK2A,CAMK2B,CAMK2G,P2RX6,NEURL1,DGKI,ARHGEF2,DCLK1,DLGAP2,DLGAP1,CHRM1,CHRM4,DLGAP3,HOMER3,CNN3,PICK1,CABP1,AKAP5,SIPA1L1,ERC2,CTNND2,ARHGAP32,DBN1,DNAJC6,MAGI2,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DNM2,SHANK1,ABI1,DRP2,EPB41L1,DMTN,EPS8,ERBB4,PTK2B,BAIAP2,CAP2,PDLIM5,NPTN,FYN,GAP43,DISC1,GNG3,GPER1,PCLO,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,NR3C1,GRM1,GRM3,GRM5,SYNPO,HNRNPK,MYLK2,KCND2,MAP2,MAP4,MAPT,DBNL,MT3,NEFH,NF1,NOS1,NRGN,NTRK2,P2RY1,PALM,PDE4B,PDPK1,PRKCG,MAPK10,PTCH1,SYNDIG1,NLGN4Y,PPP1R9A,CNKSR2,NLGN1,CLSTN1,SHANK2,CPEB4,ARFGAP1,SORCS3,RIMS1,PDZD2,CLSTN2,EPB41L3,SYT11,SYN1,ARC,SYN2,PSD3,RUSC1,ANKS1B,LRP8,GOPC,RTN4,NETO2,NETO1" GO: Cellular Component GO:0098793 presynapse 3.90E-39 4.34E-36 2.89E-37 2.20E-36 167 341 "SYN3,ACHE,ADORA1,ADORA2A,KCTD16,SYT13,DOC2A,AMPH,BIN1,PPFIA4,PPFIA2,PPFIA1,APBA2,APBB1,PPFIA3,APP,MADD,CASK,CADPS,ATP6V1G2,ATP6V0A1,SYNJ1,MTMR2,BSN,BAIAP3,CACNA1A,CACNA1B,CALB1,CALB2,HAP1,CAMK2A,SYT6,CCK,SYNGR3,DGKI,CDH2,CBARP,SYNPR,RAB3C,NRXN3,CLCN3,NRXN1,NRXN2,CLTC,PICK1,SLC32A1,SNCAIP,RIMS4,ERC2,RIMS2,SNPH,RIMS3,KCTD8,DBI,BLOC1S6,SNAP91,SV2B,SV2A,DLG4,DNM1,DPYSL2,DNM1L,SYT15,COPS4,STX2,VTI1B,SGIP1,SYT3,NPTN,BRSK1,GABBR1,GABRA2,GABRB3,GAD1,GAD2,SYT17,DISC1,CPLX2,CPLX1,C1QL1,GPER1,PCLO,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM1,GRM2,GRM3,GRM7,GRM8,HRH3,ICA1,MYLK2,SLC6A17,KCNA1,KCNA2,KCNC2,KCNH1,KCNJ10,KCNMA1,STXBP5,L1CAM,LRRC4B,SYTL4,SYT9,SCAMP5,MT3,MYO5A,NF1,NPY,NTRK2,OPHN1,P2RX7,PCDH8,PDE2A,PDE4B,EPN1,PACSIN1,POLG,PTPRN,PTPRN2,RAB3A,LRRK2,SYNDIG1,STX1B,ITSN1,NLGN1,SLC1A2,RPH3A,SLC6A9,SHANK2,LGI3,RIMS1,SNAP25,SNCB,SNCA,ERC1,STX1A,SEPT3,STXBP1,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,CADM1,WNT7A,TRIM9,SLC30A3,MFF,SLC17A7,TMEM163,SLC17A6,FZD3" GO: Cellular Component GO:0097060 synaptic membrane 2.19E-38 2.44E-35 1.53E-36 1.16E-35 152 298 "ACHE,ADORA1,ADORA2A,LRFN2,NLGN4X,KCTD16,LRRC7,LRFN1,ANK1,ANK2,ANK3,CNIH2,APBB1,LRRC4C,CASK,ARRB1,ARRB2,ATP2B1,MPDZ,SYNJ1,MTMR2,CAMK2A,CBLN1,NEURL1,DGKI,DLGAP2,DLGAP1,CHRM1,CHRM4,CHRNA4,CHRNB2,DLGAP3,NRXN1,NRXN2,HOMER3,PICK1,CABP1,AKAP5,NECTIN3,SNCAIP,SIPA1L1,RIMS4,ERC2,RIMS2,ARHGAP32,SNPH,KCTD8,DBN1,CNIH3,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM2,SHANK1,ABI1,DRP2,ENO2,EPB41L1,GPHN,ERBB2,OLFM1,NBEA,PDLIM5,NPTN,NSG1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,DISC1,GLRB,GPER1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM7,GRM8,IL1RAPL1,SYNPO,TMEM240,LRRTM3,LRRTM1,KCNA1,KCNA2,KCNB1,KCNC2,KCND2,KCNH1,KCNJ4,KCNMA1,L1CAM,LRRC4B,NTRK2,P2RY1,PALM,PCDH8,PDE2A,PRKCG,NDUFS7,PTPRZ1,IQSEC3,SYNDIG1,LRRTM4,NLGN4Y,SHC4,CNKSR2,NLGN1,CLSTN1,SLC1A2,SHANK2,RIMS1,SNAP25,FAIM2,ERC1,DDN,CLSTN2,ZC4H2,LRRC4,SEPT3,SYT11,ARC,SYP,SYT1,SYNE1,PSD3,RUSC1,ANKS1B,GOPC,SSPN,NETO1" GO: Cellular Component GO:0098589 membrane region 1.69E-31 1.89E-28 1.11E-29 8.42E-29 395 1267 "TTYH1,ACHE,ADCY2,ADCY5,ADCY6,ADCYAP1R1,SLC12A5,FZD9,ADORA1,ADORA2A,UNC5A,LRFN2,ADRB2,NLGN4X,AP2A1,AP2A2,KCTD16,LRRC7,LRFN1,ANK1,ANK2,ANK3,FGD2,CNIH2,APBB1,APC,EPB41L5,LRRC4C,APP,SHROOM2,AQP4,AQP6,CASK,ARRB1,ARRB2,NUMB,ATP1A1,ATP1A2,SLC4A4,ATP1B3,ATP2B1,ATP2B2,ATP2B3,RIPK1,BBS2,MPDZ,RGS9,HCN2,CFLAR,PROM1,DST,SYNJ1,SYNJ2,BTK,MTMR2,SGCE,CA4,CACNA1D,DDR1,CAMK2A,HIP1R,MAP7,CBLN1,SCARB1,ENTPD2,NEURL1,DGKI,CD81,ARHGEF2,SEPT7,CDH2,DLGAP2,DLGAP1,CHRM1,CHRM4,CHRNA4,CHRNB2,SLC22A6,DLGAP3,EPS15L1,CLCN3,NRXN1,NRXN2,CLTA,CLTB,CLTC,ABCG2,CNGA3,HOMER3,CNR1,PICK1,CNTFR,CNTN1,AKAP7,AKAP6,WHRN,CABP1,AKAP5,SLC4A7,MYRIP,NECTIN3,CLIP3,SNCAIP,SIPA1L1,RIMS4,CNTNAP2,ERC2,ARHGEF4,CTNND1,RIMS2,NOS1AP,MYADM,ARHGAP32,RIPOR2,SNPH,TBC1D5,ACY3,KCTD8,DAPK3,AIF1L,DBN1,DCC,HEPH,CNIH3,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,SLC29A4,DNM2,SHANK1,SLC12A6,DRD1,ABI1,DRP2,DNM1L,WDPCP,EDNRA,EDNRB,EGFR,PLEKHA1,TNK2,PLEKHO1,ENO2,MFSD10,EPB41L1,DMTN,RASGRP2,EPHB1,GPHN,STX2,EPS8,ERBB2,ERBB4,CDHR1,APC2,ADGRV1,SH3YL1,PTK2B,DLC1,FCGR1A,OLFM1,FGR,AMOTL2,SGIP1,NBEA,SORBS1,PDLIM5,NPTN,NSG1,AP4B1,FYN,MEGF11,MEGF10,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,AHCYL1,RAPGEF6,NCKAP1,GAP43,DISC1,INPP5K,IGSF5,GLRB,GNAS,FERMT2,GPM6B,MCHR1,GPER1,GRK4,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM7,GRM8,IL1RAPL1,BVES,AP4S1,PACSIN2,SYNPO,HPCA,CFAP126,HSP90AA1,HTR2A,IL6R,TMEM240,LRRTM3,LRRTM1,ITGAV,JAK2,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND2,KCND3,KCNH1,KCNJ4,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNQ3,L1CAM,LRRC4B,LAMP2,SYTL4,MOG,MTTP,MDGA1,MYO6,MYO7A,NOS1,SLC11A2,HCN1,NTRK2,DDR2,OCRL,OLR1,OXTR,P2RY1,SNTG1,PALM,PCDH8,PDE2A,PDE4A,PDE4D,ABCB1,PKD1,PLCD1,PLEC,FXYD1,EPN1,LRP12,PACSIN1,DRAM2,TMEM235,PRKAB2,PRKCB,PRKCG,PRKCZ,MAPK3,PRPH,CNNM2,NDUFS7,PTCH1,PTH1R,PTK2,PTPRO,PTPRZ1,TMEM231,IQSEC3,RASGRF1,RDX,RET,ROBO1,KIRREL1,ROBO2,ROM1,LRRK2,SYNDIG1,ATAT1,WLS,LRRTM4,NLGN4Y,ITSN1,FERMT1,SHC4,CNKSR2,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC2A5,SLC8A2,SLC8A1,SHANK2,SLC12A2,SLC14A1,SLCO1A2,SLC22A4,RIMS1,SNAP25,FAIM2,TNIK,FNBP1,ERC1,UNC5B,DDN,CLASP2,CLSTN2,EPB41L3,ZC4H2,LRRC4,ERBIN,FCHO1,MAPK8IP3,KANK1,SEPT3,AJAP1,SYT11,MLC1,SYNE2,ARC,SYP,SYT1,MTCL1,WWC1,SYNE1,PSD3,TEK,TF,CRB1,AP4E1,GPR161,HHIP,TIAM1,TJP1,TLR4,TNFRSF1B,TNR,TPM1,RGMB,TRPC1,RUSC1,TSC2,RFTN2,CADM1,VLDLR,BEST1,P2RY12,LAT2,CLDND1,XPO1,NDRG4,CRB2,ANKS1B,LAMP5,LRP8,GOPC,FZD3,VANGL2,SSPN,PIANP,IFT88,NETO1,SLC4A10,SPATA13" GO: Cellular Component GO:0033267 axon part 6.41E-31 7.13E-28 3.96E-29 3.01E-28 144 309 "ERMN,ADORA1,ADORA2A,LRRC7,AMPH,BIN1,ANK1,ANK3,CNTNAP1,APBB1,KCNAB2,APC,APP,SHTN1,SPTBN4,ATP6V0A1,KIF1A,SYNJ1,SYNJ2,CACNA1B,CALB1,CALB2,HAP1,CAMK2D,CCK,DGKI,SEPT7,CDH8,CHRM1,CHRM4,CLCN3,NRXN1,CLTC,CRHBP,SLC32A1,AATK,CNTNAP2,ERC2,BOC,DBN1,BLOC1S6,SNAP91,PARD6A,SV2B,SV2A,DLG2,DLG4,DNM1,DPYSL2,DRD1,TUBB4A,OLFM1,SGIP1,GABBR1,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPM6A,GPER1,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM7,KIF3A,HNRNPK,MYLK2,KCNA1,KCNA2,KCNA6,KCNC1,KCNC2,KCNH1,KCNJ11,KCNK2,KCNMA1,KCNQ2,KCNQ3,L1CAM,MAG,MAPT,MBP,BLOC1S2,NPY,NRCAM,HCN1,NTRK2,OPA1,OPHN1,PDYN,PENK,EPN1,PACSIN1,POLG,PRKCZ,PTCH1,PTPRN,PTPRN2,RAB3A,RGS10,ROBO1,ROBO2,LRRK2,KCNIP3,SCN2A,SCN8A,ITSN1,SLC1A2,SIRT2,SNAP25,SNCB,SNCA,PALLD,SPTAN1,KIF1B,NFASC,CLASP2,EPB41L3,MAPK8IP3,STXBP1,VAMP1,SYN1,SYN2,SYP,SYT1,COBL,CNTN2,TIAM1,TNFRSF1B,PARD3,CADM1,UCHL1,KCNAB1,SLC17A6,AP3B2" GO: Cellular Component GO:0030054 cell junction 8.63E-31 9.60E-28 5.05E-29 3.84E-28 377 1200 "SYN3,ACHE,ACTN1,ACTN2,PLEKHG5,DSCAML1,ADCYAP1R1,ADD1,ADD3,ADRA1B,LRFN2,NLGN4X,KCTD16,LRRC7,ALCAM,DOC2A,AMPH,LRFN1,CDC42BPA,ANK2,ANK3,CNIH2,PPFIA1,PKP4,KCNAB2,APC,EPB41L5,LRRC4C,APP,SHROOM2,AQP4,PRX,CASK,SPTBN4,CADPS,NUMB,ATP1A1,ATP1A2,STX16,ATP2A2,ATP2B1,ATP2B2,SLC2A11,CADM3,ADAM15,ADGRB1,MPDZ,DST,ARHGEF7,BSN,WASF1,CALB2,HAP1,CAMK2A,CAMK2D,SYT6,CBLN1,CLDN10,KRIT1,P2RX6,SYNGR3,NEURL1,CD81,ARHGEF2,CDC42,CDH2,LGI1,MAGI1,DLGAP2,DLGAP1,CBARP,CHRM1,CHRM4,SYNPR,CHRNA4,CHRNB2,JAM2,ARHGAP22,DLGAP3,NRXN1,CLTC,TJP2,HOMER3,CNN3,ARHGEF6,PICK1,AKAP6,CABP1,NECTIN3,CDC42BPB,AKAP12,SIPA1L1,RIMS4,ERC2,CTNND1,CTNND2,RIMS2,MYADM,ARHGAP32,SNPH,ARHGAP24,RIMS3,KCTD8,AIF1L,GIT2,DBN1,CNIH3,MAGI2,PARD6A,SV2B,SV2A,DLG2,DLG3,DLG4,GRIN3A,DMD,CD99L2,DNM2,SHANK1,ABI1,DRP2,ATN1,PDCD6IP,DSCAM,DTNA,DNM1L,EGFR,ABI2,SORBS3,COPS4,TNK2,RGS17,C8orf37,EPB41,EPB41L2,RASGRP2,SEZ6,EPHA5,GPHN,STX2,EPS8,NRN1,FABP7,PTK2B,DLC1,FER,OLFM1,FGF13,FGFR3,AMOTL2,FHL1,EVL,FLNC,FLT1,NBEA,SORBS1,PDLIM5,BRSK1,FYB1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,NCKAP1,GAP43,DISC1,STARD10,IGSF5,GJB1,RND1,GLRB,FERMT2,GPER1,PCLO,GRIA1,GRIA2,GRIA4,PARD3B,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM2,GSN,BVES,PACSIN2,SYNPO,HNRNPK,CPT1C,OPALIN,FAAP20,ATCAY,ICA1,DOCK7,TJAP1,TMEM240,SLC6A17,LRRTM3,LRRTM1,ITGA7,ITGAV,JAK1,KCNA1,KCNA2,OLFM3,KCNB1,KCNC2,KCND2,KCNJ4,KCNJ11,KCNK1,KIFC3,KIT,STXBP5,L1CAM,LRRC4B,LIG4,LIMS1,SYT9,LDLRAD3,SCAMP5,AFDN,CD200,GIT1,DBNL,CTNNA3,LAYN,NCAM1,NFIA,DDR2,OPHN1,CLDN11,OXTR,P2RX7,PCDHGC3,PCDH8,PCDH9,PDPK1,ABCB1,NLGN3,PIK3R1,ZFYVE21,PLEC,PMP22,SDK2,EPB41L4B,PACSIN1,SH3KBP1,CEP41,PRKCG,PKN2,PRKCZ,MAPK3,LAMA1,PTK2,PTPRN,PTPRN2,RDX,PRRT2,RGS12,PRIMA1,KIRREL1,RPL38,LRRK2,SYNDIG1,ATAT1,SCN2A,SCN4B,LRRTM4,PUF60,NLGN4Y,ITSN1,PPP1R9A,FERMT1,ASAP3,SHC4,MAGI3,NLGN1,CLSTN1,RPH3A,LIMS2,SLC8A1,SLC8A3,SIRT2,SHANK2,LGI3,CDK5RAP2,RIMS1,SNAP25,SNCA,FAIM2,PALLD,USP33,PDZD2,ARHGAP26,SPTAN1,NFASC,CLASP2,EPB41L3,ZC4H2,LRRC4,ERBIN,MPRIP,CEP68,STX1A,SEPT3,AJAP1,SYT11,MLC1,SYNE2,VAMP1,SYN1,ARC,SYN2,SYP,SYT1,SYT4,SYT5,KAZN,DNMBP,PDLIM2,ADGRL3,VWC2,DMXL2,RPGRIP1L,CLASP1,PSD3,OBSL1,TNS2,TEK,TIAM1,TJP1,RIMBP2,PRRT1,PARD3,TNS1,TPM4,ZNF384,SYNPO2,RUSC1,HEPACAM,CADM1,AMOT,FRRS1L,FLRT2,FLRT1,VAV1,XRCC4,TRIM9,ANKS1B,SLC30A3,MFF,CADM2,SLC17A7,TMEM163,WNK3,SLC17A6,GOPC,GJC2,NUP214,VANGL2,SSPN,PIANP,FRMD6,NETO1" GO: Cellular Component GO:0098590 plasma membrane region 3.52E-30 3.92E-27 1.96E-28 1.49E-27 337 1041 "TTYH1,ACHE,ADCY6,ADCYAP1R1,SLC12A5,FZD9,ADORA1,ADORA2A,UNC5A,LRFN2,ADRB2,NLGN4X,AP2A1,KCTD16,LRRC7,LRFN1,ANK1,ANK2,ANK3,FGD2,CNIH2,APBB1,APC,EPB41L5,LRRC4C,SHROOM2,AQP4,AQP6,CASK,ARRB1,ARRB2,NUMB,ATP1A1,ATP1A2,SLC4A4,ATP1B3,ATP2B1,ATP2B2,BBS2,MPDZ,RGS9,HCN2,PROM1,DST,SYNJ1,SYNJ2,MTMR2,SGCE,CA4,CACNA1D,DDR1,CAMK2A,MAP7,CBLN1,SCARB1,ENTPD2,NEURL1,DGKI,CD81,ARHGEF2,SEPT7,CDH2,DLGAP2,DLGAP1,CHRM1,CHRM4,CHRNA4,CHRNB2,SLC22A6,DLGAP3,CLCN3,NRXN1,NRXN2,CLTB,ABCG2,CNGA3,HOMER3,PICK1,CNTFR,AKAP7,AKAP6,WHRN,CABP1,AKAP5,SLC4A7,MYRIP,NECTIN3,SNCAIP,SIPA1L1,RIMS4,CNTNAP2,ERC2,ARHGEF4,CTNND1,RIMS2,NOS1AP,ARHGAP32,RIPOR2,SNPH,ACY3,KCTD8,AIF1L,DBN1,HEPH,CNIH3,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,SLC29A4,DNM2,SHANK1,SLC12A6,DRD1,ABI1,DRP2,WDPCP,EGFR,PLEKHA1,PLEKHO1,ENO2,MFSD10,EPB41L1,DMTN,RASGRP2,GPHN,STX2,EPS8,ERBB2,ERBB4,CDHR1,APC2,ADGRV1,SH3YL1,DLC1,OLFM1,FGR,AMOTL2,NBEA,SORBS1,PDLIM5,NPTN,NSG1,MEGF11,MEGF10,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,AHCYL1,RAPGEF6,NCKAP1,GAP43,DISC1,INPP5K,IGSF5,GLRB,FERMT2,MCHR1,GPER1,GRK4,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM7,GRM8,IL1RAPL1,BVES,PACSIN2,SYNPO,HPCA,CFAP126,HSP90AA1,HTR2A,IL6R,TMEM240,LRRTM3,LRRTM1,ITGAV,JAK2,KCNA1,KCNA2,KCNB1,KCNC1,KCNC2,KCND2,KCND3,KCNH1,KCNJ4,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,L1CAM,LRRC4B,SYTL4,MTTP,MYO6,MYO7A,NOS1,SLC11A2,HCN1,NTRK2,DDR2,OXTR,P2RY1,SNTG1,PALM,PCDH8,PDE2A,PDE4A,PDE4D,ABCB1,PKD1,PLEC,FXYD1,PACSIN1,DRAM2,TMEM235,PRKAB2,PRKCB,PRKCG,PRKCZ,MAPK3,PRPH,CNNM2,NDUFS7,PTCH1,PTH1R,PTK2,PTPRO,PTPRZ1,TMEM231,IQSEC3,RASGRF1,RDX,ROBO1,KIRREL1,ROBO2,ROM1,LRRK2,SYNDIG1,WLS,LRRTM4,NLGN4Y,FERMT1,SHC4,CNKSR2,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC2A5,SLC8A2,SLC8A1,SHANK2,SLC12A2,SLC14A1,SLCO1A2,SLC22A4,RIMS1,SNAP25,FAIM2,TNIK,ERC1,DDN,CLASP2,CLSTN2,EPB41L3,ZC4H2,LRRC4,ERBIN,MAPK8IP3,KANK1,SEPT3,AJAP1,SYT11,MLC1,SYNE2,ARC,SYP,SYT1,MTCL1,WWC1,SYNE1,PSD3,TEK,TF,CRB1,GPR161,HHIP,TIAM1,TJP1,TPM1,TRPC1,RUSC1,TSC2,CADM1,BEST1,P2RY12,CLDND1,NDRG4,ANKS1B,LAMP5,LRP8,GOPC,FZD3,VANGL2,SSPN,PIANP,NETO1,SLC4A10,SPATA13" GO: Cellular Component GO:0045211 postsynaptic membrane 2.14E-27 2.39E-24 1.14E-25 8.63E-25 112 225 "ACHE,ADORA1,ADORA2A,LRFN2,NLGN4X,KCTD16,LRRC7,LRFN1,ANK1,ANK2,ANK3,CNIH2,APBB1,LRRC4C,ARRB1,ARRB2,MPDZ,CBLN1,NEURL1,DLGAP2,DLGAP1,CHRM1,CHRM4,CHRNA4,CHRNB2,DLGAP3,HOMER3,PICK1,CABP1,NECTIN3,SIPA1L1,ARHGAP32,KCTD8,DBN1,CNIH3,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM2,SHANK1,ABI1,DRP2,GPHN,ERBB2,NBEA,PDLIM5,NSG1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,DISC1,GLRB,GPER1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM3,GRM7,IL1RAPL1,SYNPO,LRRTM3,LRRTM1,KCNB1,KCNC2,KCND2,KCNJ4,KCNMA1,NTRK2,P2RY1,PCDH8,PTPRZ1,IQSEC3,SYNDIG1,LRRTM4,NLGN4Y,SHC4,CNKSR2,NLGN1,CLSTN1,SHANK2,FAIM2,CLSTN2,ZC4H2,LRRC4,ARC,SYNE1,PSD3,RUSC1,ANKS1B,GOPC,SSPN,NETO1" GO: Cellular Component GO:0034702 ion channel complex 4.71E-23 5.24E-20 2.38E-21 1.81E-20 125 291 "TTYH1,ABHD6,KCNT1,DPP10,CNIH2,CNTNAP1,KCNAB2,ASPH,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,SHISA7,CACNA2D2,CHRNA4,CHRNB2,DLGAP3,AKAP6,CNTNAP2,NOS1AP,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DPP6,ABCC9,CACNG7,KCNMB2,EPS8,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,CPT1C,SHISA6,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,STXBP5,TTYH2,NOS1,PDE4B,PDE4D,BEST3,FXYD1,PTPA,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,NLGN1,SHANK2,SNAP25,SCN3B,STX1A,ABCC8,CNTN2,VWC2,LRRC8A,KCNE5,BEST1,PORCN,KCNT2,KCNAB1" GO: Cellular Component GO:0043197 dendritic spine 6.92E-23 7.70E-20 3.35E-21 2.54E-20 81 151 "ASIC2,ASIC1,ACTN1,ACTN2,ADD1,ADORA1,ADRB2,LRRC7,CNIH2,APBB1,ALS2,APP,ARRB1,ARRB2,ATP1A2,ATP1A3,CDK5R1,MTMR2,CANX,P2RX6,NEURL1,DGKI,DLGAP3,CNN3,AKAP5,SIPA1L1,CTNND1,ARHGAP32,FRMPD4,DBN1,DLG4,SHANK1,DRD1,SEZ6,BAIAP2,GABBR1,GPM6A,GPER1,RAPGEF4,GRIA1,GRIA2,GRIN1,NR3C1,GRM1,GRM3,GRM5,SYNPO,HNRNPK,HPCA,MYLK2,ITPKA,KCND2,KCNN2,LAMA2,MT3,NOS1,NRGN,NTRK2,OPHN1,PALM,PDE4B,PTPRO,PTPRZ1,RGS10,SYNDIG1,PPP1R9A,NLGN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,SLC8A3,SHANK2,LRRC4,SYT11,ARC,SYNE1,TIAM1,ZMYND8,ANKS1B,FXR1" GO: Cellular Component GO:0044309 neuron spine 2.14E-22 2.38E-19 9.91E-21 7.52E-20 81 153 "ASIC2,ASIC1,ACTN1,ACTN2,ADD1,ADORA1,ADRB2,LRRC7,CNIH2,APBB1,ALS2,APP,ARRB1,ARRB2,ATP1A2,ATP1A3,CDK5R1,MTMR2,CANX,P2RX6,NEURL1,DGKI,DLGAP3,CNN3,AKAP5,SIPA1L1,CTNND1,ARHGAP32,FRMPD4,DBN1,DLG4,SHANK1,DRD1,SEZ6,BAIAP2,GABBR1,GPM6A,GPER1,RAPGEF4,GRIA1,GRIA2,GRIN1,NR3C1,GRM1,GRM3,GRM5,SYNPO,HNRNPK,HPCA,MYLK2,ITPKA,KCND2,KCNN2,LAMA2,MT3,NOS1,NRGN,NTRK2,OPHN1,PALM,PDE4B,PTPRO,PTPRZ1,RGS10,SYNDIG1,PPP1R9A,NLGN1,SLC1A2,SLC1A3,SLC8A2,SLC8A1,SLC8A3,SHANK2,LRRC4,SYT11,ARC,SYNE1,TIAM1,ZMYND8,ANKS1B,FXR1" GO: Cellular Component GO:1902495 transmembrane transporter complex 2.50E-21 2.79E-18 1.11E-19 8.46E-19 132 327 "TTYH1,ABHD6,KCNT1,DPP10,CNIH2,CNTNAP1,KCNAB2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,HCN2,BCS1L,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,SHISA7,CACNA2D2,CHRNA4,CHRNB2,DLGAP3,CNGA3,AKAP6,CNTNAP2,NOS1AP,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DPP6,ABCC9,CACNG7,KCNMB2,EPS8,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,CPT1C,SHISA6,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,STXBP5,TTYH2,NOS1,PDE4B,PDE4D,BEST3,FXYD1,PTPA,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,NLGN1,SHANK2,SNAP25,SCN3B,STX1A,ABCC8,CNTN2,VWC2,LRRC8A,KCNE5,BEST1,PORCN,KCNT2,KCNAB1" GO: Cellular Component GO:0030427 site of polarized growth 5.40E-21 6.01E-18 2.31E-19 1.76E-18 90 187 "GPRIN1,NDRG2,APBB1,APBB2,APC,ALS2,APP,SHTN1,CDK5R1,ARHGEF7,CALM1,HAP1,PTBP2,CBARP,NRXN1,CLU,NGEF,CNR1,WHRN,AATK,CSNK1E,ERC2,CTNND1,NRSN1,BOC,DBN1,DCC,TIAM2,PARD6A,DLG3,DNM2,DPYSL2,ABI1,DSCAM,FRY,TNK2,ELAVL4,EPS8,PTK2B,OLFM1,FGF13,DCTN2,GAP43,GPM6A,PCLO,RAPGEF4,STMN2,GRIA2,GRIN1,DOCK7,LRRTM1,KLC1,L1CAM,ZFYVE27,MAPT,MYO5A,NCAM1,NTRK2,PCDH9,TMOD2,PTCH1,PTPRO,PTPRZ1,RASGRF1,CRTAC1,MYH14,LRRK2,PPP1R9A,SIRT2,SHANK2,SNAP25,SNCB,SNCA,PALLD,CLASP2,COBL,EXOC7,PCDHGB1,FRYL,DICER1,SIRT1,TIAM1,PARD3,TPM3,TSC1,TSC2,LAMP5,MAP3K12,GDPD5,STMN4" GO: Cellular Component GO:0030426 growth cone 9.96E-21 1.11E-17 4.11E-19 3.12E-18 88 182 "GPRIN1,NDRG2,APBB1,APBB2,APC,ALS2,APP,SHTN1,CDK5R1,ARHGEF7,CALM1,HAP1,PTBP2,CBARP,NRXN1,CLU,NGEF,CNR1,WHRN,AATK,CSNK1E,ERC2,CTNND1,NRSN1,BOC,DBN1,DCC,TIAM2,PARD6A,DLG3,DNM2,DPYSL2,ABI1,DSCAM,TNK2,ELAVL4,EPS8,PTK2B,OLFM1,FGF13,DCTN2,GAP43,GPM6A,PCLO,RAPGEF4,STMN2,GRIA2,GRIN1,DOCK7,LRRTM1,KLC1,L1CAM,ZFYVE27,MAPT,MYO5A,NCAM1,NTRK2,PCDH9,TMOD2,PTCH1,PTPRO,PTPRZ1,RASGRF1,CRTAC1,MYH14,LRRK2,PPP1R9A,SIRT2,SHANK2,SNAP25,SNCB,SNCA,PALLD,CLASP2,COBL,EXOC7,PCDHGB1,DICER1,SIRT1,TIAM1,PARD3,TPM3,TSC1,TSC2,LAMP5,MAP3K12,GDPD5,STMN4" GO: Cellular Component GO:1990351 transporter complex 1.67E-20 1.86E-17 6.65E-19 5.05E-18 132 333 "TTYH1,ABHD6,KCNT1,DPP10,CNIH2,CNTNAP1,KCNAB2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,HCN2,BCS1L,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,SHISA7,CACNA2D2,CHRNA4,CHRNB2,DLGAP3,CNGA3,AKAP6,CNTNAP2,NOS1AP,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DPP6,ABCC9,CACNG7,KCNMB2,EPS8,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,KCNMB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,CPT1C,SHISA6,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,STXBP5,TTYH2,NOS1,PDE4B,PDE4D,BEST3,FXYD1,PTPA,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,NLGN1,SHANK2,SNAP25,SCN3B,STX1A,ABCC8,CNTN2,VWC2,LRRC8A,KCNE5,BEST1,PORCN,KCNT2,KCNAB1" GO: Cellular Component GO:0044304 main axon 1.02E-19 1.13E-16 3.90E-18 2.96E-17 49 74 "ERMN,ADORA1,ADORA2A,LRRC7,BIN1,ANK1,ANK3,CNTNAP1,APBB1,KCNAB2,APP,SPTBN4,CAMK2D,CCK,CRHBP,CNTNAP2,DLG2,DLG4,DNM1,TUBB4A,GABBR1,KCNA1,KCNA2,KCNC1,KCNC2,KCNH1,KCNJ11,KCNQ2,KCNQ3,MAG,MAPT,MBP,NRCAM,ROBO1,ROBO2,SCN2A,SCN8A,SLC1A2,SIRT2,SPTAN1,NFASC,EPB41L3,MAPK8IP3,CNTN2,TIAM1,TNFRSF1B,PARD3,CADM1,KCNAB1" GO: Cellular Component GO:0031252 cell leading edge 5.05E-19 5.62E-16 1.87E-17 1.42E-16 144 389 "ACTN1,PLEKHG5,SLC12A5,ADORA1,ADORA2A,UNC5A,AMPH,CDC42BPA,ANK1,FGD2,APBB1,APBB2,APC,EPB41L5,GAS7,DGKZ,ALS2,APP,SHTN1,ATP2B1,HCN2,DST,SYNJ2,ARHGEF7,SGCE,WASF1,CACNA1D,LDB2,ARHGEF2,CDC42,CDH2,ARHGEF6,AKAP5,CDC42BPB,SH2B1,CNTNAP2,ARHGEF4,CTNND1,MYADM,AIF1L,DBN1,DCTN1,TIAM2,PARD6A,DNM2,ABI1,ATN1,ABI2,PLEKHA1,PLEKHO1,RASGRP2,MTSS1L,STX2,EPS8,APC2,SH3YL1,PTK2B,DLC1,FER,BAIAP2,FGR,EVL,GABBR1,GABRA2,GABRG2,NCKAP1,IQGAP2,INPP5K,WASF3,GNAS,FERMT2,GPER1,STMN2,GRIA1,GRIN1,CIT,GSN,PACSIN2,HPCA,HSP90AA1,ITGAV,KCNA2,KCNB1,KCNC1,KCNC2,KCNH1,KCNJ11,MKLN1,DBNL,CTNNA3,LAYN,MYO5A,MYO6,HCN1,SNTG1,PALM,PDE4A,SSH1,PACSIN1,PKN2,PRKCZ,PSD,BCAS3,GDPD2,PTK2,PTPN13,PTPRO,PTPRZ1,RDX,ROBO1,ROBO2,WLS,CLIP1,S100B,ITSN1,PPP1R9A,FERMT1,ASAP3,ABLIM3,SLC1A2,CCDC88A,SNAP25,PALLD,DDN,CLASP2,SAMSN1,EPB41L3,MAPK8IP3,KANK1,FGD4,SYNE2,COBL,MCF2L,WWC1,TIAM1,MTMR14,TPM1,TSC1,AMOT,PLEKHH2,WIPF1,LAMP5,DOCK8,SPATA13" GO: Cellular Component GO:0070382 exocytic vesicle 1.06E-17 1.18E-14 3.81E-16 2.89E-15 80 172 "SYN3,DOC2A,AMPH,BIN1,APBA2,MADD,ATP6V1G2,MTMR2,HAP1,SYT6,SYNGR3,DGKI,CBARP,SYNPR,RAB3C,CLCN3,AKAP7,SLC32A1,SNCAIP,DBI,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM1L,COPS4,STX2,VTI1B,SYT3,BRSK1,GABBR1,GABRA2,GAD2,SYT17,DISC1,GRIA1,GRIA2,GRIN1,ICA1,MYLK2,IGF1,SLC6A17,STXBP5,SYTL4,SYT9,SCAMP5,MT3,MYO5A,PDE4B,SYTL2,PTPRN,PTPRN2,RAB3A,LRRK2,STX1B,RPH3A,LGI3,SNAP25,SNCA,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,CADM1,TRIM9,SLC30A3,MFF,SLC17A7,TMEM163,SLC17A6" GO: Cellular Component GO:0042734 presynaptic membrane 3.44E-17 3.83E-14 1.20E-15 9.08E-15 47 76 "ACHE,ADORA1,ADORA2A,KCTD16,APBB1,CASK,CAMK2A,NRXN1,NRXN2,PICK1,SNCAIP,ERC2,RIMS2,SNPH,KCTD8,SNAP91,NPTN,GABBR1,GAD2,GPER1,GRIA2,GRIK1,GRIK2,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM7,GRM8,KCNA1,KCNA2,KCNC2,KCNH1,KCNMA1,L1CAM,LRRC4B,PCDH8,PDE2A,SLC1A2,RIMS1,SNAP25,ERC1,SEPT3,SYT11,SYP,SYT1" GO: Cellular Component GO:0008021 synaptic vesicle 4.53E-17 5.05E-14 1.53E-15 1.16E-14 74 156 "SYN3,DOC2A,AMPH,BIN1,APBA2,MADD,ATP6V1G2,MTMR2,HAP1,SYT6,SYNGR3,DGKI,CBARP,SYNPR,RAB3C,CLCN3,SLC32A1,SNCAIP,DBI,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM1L,COPS4,STX2,VTI1B,BRSK1,GABBR1,GABRA2,GAD2,DISC1,GRIA1,GRIA2,GRIN1,ICA1,MYLK2,SLC6A17,STXBP5,SYT9,SCAMP5,MT3,MYO5A,PDE4B,PTPRN,PTPRN2,RAB3A,LRRK2,STX1B,RPH3A,LGI3,SNAP25,SNCA,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,CADM1,TRIM9,SLC30A3,MFF,SLC17A7,TMEM163,SLC17A6" GO: Cellular Component GO:0044306 neuron projection terminus 4.96E-17 5.52E-14 1.62E-15 1.23E-14 87 199 "ADORA1,AMPH,BIN1,KCNAB2,APC,APP,ATP6V0A1,SYNJ1,SYNJ2,BSN,CACNA1B,CALB1,CALB2,HAP1,CCK,DGKI,SEPT7,CDH8,CHRM1,CHRM4,CLCN3,CLTC,CRHBP,SLC32A1,ERC2,SNAP91,SV2B,SV2A,DLG4,DMD,DPYSL2,DRD1,SGIP1,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPER1,PCLO,RAPGEF4,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM7,SCRG1,HNRNPK,MYLK2,KCNA1,KCNA2,KCNA6,KCNC2,KCNK2,KCNMA1,L1CAM,NPY,HCN1,NTRK2,OPHN1,PDYN,PENK,EPN1,PACSIN1,POLG,PTPRN,PTPRN2,RAB3A,RGS10,LRRK2,KCNIP3,ITSN1,SNAP25,SNCB,SNCA,STXBP1,VAMP1,SYN1,SYN2,SYP,SYT1,UCHL1,FLRT1" GO: Cellular Component GO:0048786 presynaptic active zone 1.41E-16 1.57E-13 4.49E-15 3.41E-14 30 37 "ADORA1,ADORA2A,PPFIA4,PPFIA2,PPFIA1,PPFIA3,BSN,DGKI,CDH2,SLC32A1,RIMS4,ERC2,RIMS2,RIMS3,SV2A,GAD1,GPER1,PCLO,GRM3,GRM7,KCNMA1,NTRK2,SHANK2,RIMS1,ERC1,SYT11,SYN1,SYP,SLC17A7,FZD3" GO: Cellular Component GO:0031256 leading edge membrane 2.26E-16 2.51E-13 6.98E-15 5.30E-14 71 150 "SLC12A5,ADORA1,ADORA2A,UNC5A,AMPH,ANK1,FGD2,APC,EPB41L5,ATP2B1,HCN2,SYNJ2,SGCE,CACNA1D,ARHGEF2,CDC42,AKAP5,CNTNAP2,ARHGEF4,AIF1L,DNM2,PLEKHA1,PLEKHO1,RASGRP2,EPS8,APC2,SH3YL1,DLC1,FGR,GABBR1,GABRA2,GABRG2,NCKAP1,INPP5K,FERMT2,GPER1,GRIA1,GRIN1,PACSIN2,HPCA,HSP90AA1,ITGAV,KCNA2,KCNB1,KCNC1,KCNC2,KCNH1,KCNJ11,MYO6,HCN1,SNTG1,PALM,PDE4A,PACSIN1,PTPRZ1,ROBO1,ROBO2,WLS,FERMT1,SLC1A2,DDN,CLASP2,EPB41L3,MAPK8IP3,KANK1,SYNE2,WWC1,TIAM1,TPM1,LAMP5,SPATA13" GO: Cellular Component GO:0008328 ionotropic glutamate receptor complex 1.25E-15 1.39E-12 3.76E-14 2.86E-13 35 50 "ABHD6,CNIH2,SHISA7,DLGAP3,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,CACNG7,EPS8,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,CPT1C,SHISA6,OLFM3,LRRTM4,NLGN1,SHANK2,VWC2,PORCN" GO: Cellular Component GO:0043679 axon terminus 2.75E-15 3.06E-12 8.06E-14 6.12E-13 80 186 "ADORA1,AMPH,BIN1,KCNAB2,APP,ATP6V0A1,SYNJ1,SYNJ2,CACNA1B,CALB1,CALB2,HAP1,CCK,DGKI,SEPT7,CDH8,CHRM1,CHRM4,CLCN3,CLTC,CRHBP,SLC32A1,ERC2,SNAP91,SV2B,SV2A,DPYSL2,DRD1,SGIP1,GABRB3,GAD1,CPLX2,CPLX1,GLUL,GPER1,PCLO,RAPGEF4,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM7,HNRNPK,MYLK2,KCNA1,KCNA2,KCNA6,KCNC2,KCNK2,KCNMA1,L1CAM,NPY,HCN1,NTRK2,OPHN1,PDYN,PENK,EPN1,PACSIN1,POLG,PTPRN,PTPRN2,RAB3A,RGS10,LRRK2,KCNIP3,ITSN1,SNAP25,SNCB,SNCA,STXBP1,VAMP1,SYN1,SYN2,SYP,SYT1" GO: Cellular Component GO:0031226 intrinsic component of plasma membrane 8.16E-15 9.08E-12 2.33E-13 1.77E-12 433 1714 "KCNH8,ASIC2,ASIC1,ABHD6,ADCY2,ADCY6,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,UNC5A,ADORA3,ESYT2,ADRA1D,ADRA1B,ADRB2,NLGN4X,SLC24A4,KIAA1324,C1QTNF1,SEMA6A,ALCAM,PCDH10,ALK,KCNT1,SYT13,DPP10,CNIH2,CNTNAP1,KCNAB2,APP,LGR5,AQP4,AQP6,SLC7A14,IGDCC4,ASGR1,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CADM3,ADAM23,ADGRB1,HCN2,PROM1,BMPR1B,ST3GAL5,SGCE,C5,CA4,CACNA1D,DDR1,CACNB2,CALM1,SLC25A14,RHBDL1,SHISA7,CCKBR,SLC5A11,SLC16A4,P2RX6,SCARB1,CD81,DCLK1,ADGRG1,ASIC3,CHRM1,CHRM4,CHRNA4,CHRNB2,JAM2,SLC22A6,DLGAP3,NRXN3,NRXN1,SLC24A2,FADS2,RAB26,CNGA3,CNR1,CNTFR,SLC4A7,SLC4A8,GAL3ST1,IGDCC3,CP,NECTIN3,SLC32A1,ABCG1,TENM4,CSF1R,CSF2RA,CSF3R,CNTNAP2,PLXNA4,CALY,CX3CR1,NOS1AP,CYBB,BOC,SIRPA,CNIH3,TMEM130,PLPPR4,DLG2,DLG3,DLG4,GRIN3A,CDON,SHANK1,SLC12A6,DPP6,DRD1,DSCAM,ABCC5,ABCC9,TSPAN5,EDNRA,EDNRB,CACNG7,EFNA3,EFNB3,APH1A,PLXNC1,RASA4,TENM1,CALCRL,EPHA5,EPHB1,KCNMB2,SLC43A2,EPS8,IGSF6,CDHR1,TLR7,SIRPB1,NRN1,F3,REEP2,CACNG3,CACNG2,PTK2B,OLFM1,FGFR1,FGFR3,SEMA6C,SEMA4D,ATP13A4,FLT1,FOLH1,FOLR2,SORBS1,HVCN1,ATP2C1,CSPG5,NRG3,GABBR1,GABRA1,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GALR1,NEU3,GGTA1P,GGT7,GGT5,GHR,LYVE1,NTNG2,GLRB,GPR75,PCDH11X,KCNMB4,GP1BB,PRLHR,GPR12,GPR17,GPR19,GPR22,LPAR4,MCHR1,GPER1,GPR34,GPR37,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,BTN2A1,MFSD2A,SLC2A6,HAS2,PTGDR2,HRH3,NCKAP1L,CPT1C,SHISA6,HTR2A,HTR5A,IL6R,IL6ST,IL11RA,SLC6A17,ITGA7,ITGAM,ITGAV,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KLRC2,STXBP5,KTN1,LIFR,MMP16,MMP17,CD200,MPP2,MSR1,MDGA1,HNRNPM,P2RY13,NCF2,NF1,SLCO1C1,NINJ2,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,DDR2,GPR88,OLR1,OPRL1,CLDN11,OXTR,P2RX7,P2RY1,KCNK10,PALM,PCDHGC3,PCDH8,PCDH9,PDGFRA,ENPP2,SLC10A4,GPR85,BEST3,NLGN3,PKD1,FXYD1,PCDH18,PLXNB1,PLXNB3,TRHDE,LRP12,PILRA,SLC26A11,SLC22A23,PTAFR,PTCH1,PLPPR1,PTH1R,PTPRB,PTPRD,PTPRG,PTPRH,PTPRN2,PTPRO,PTPRZ1,SLC6A15,RET,RGR,PRIMA1,ROBO1,ROM1,EPHA10,LGR4,PLPPR3,SYNDIG1,KCNIP3,KCNIP2,KCNIP1,RYR1,SEMA6D,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,ASIC4,IL17RB,SELL,RASA3,NLGN4Y,NTNG1,NLGN1,SLC1A2,SLC4A3,SLC1A6,SLC2A5,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SHANK2,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SNAP25,SCN3B,SPTB,SSTR1,SSTR2,APOM,STX1A,SYT11,ABCC8,VAMP1,TMEM150C,SYPL1,TACR1,CNTN2,ADGRL3,VWC2,PCDHB15,SLC19A3,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,TEK,ATP13A2,TGFBR3,HHIP,TIE1,ICAM5,TLR4,TNFRSF1B,RGMB,TRO,TRPC1,TRPC3,TRPM2,NTSR2,KCNE5,CADM1,FLRT2,FLRT1,PLPPR2,VIPR2,BEST1,TSPAN11,P2RY12,PORCN,SLC13A3,KCNK12,KCNT2,PLPP4,SLC26A10,PLPPR5,SLC30A3,CADM2,SLC38A1,KCNAB1,SLC39A12,SSPN,SLC4A10" GO: Cellular Component GO:0034703 cation channel complex 1.05E-14 1.17E-11 2.92E-13 2.21E-12 76 176 "KCNT1,DPP10,CNTNAP1,KCNAB2,ASPH,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CACNA2D2,AKAP6,CNTNAP2,NOS1AP,DLG2,DLG4,DPP6,ABCC9,CACNG7,KCNMB2,CACNG3,CACNG2,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,NOS1,PDE4B,PDE4D,PTPA,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SNAP25,SCN3B,STX1A,ABCC8,CNTN2,KCNE5,KCNT2,KCNAB1" GO: Cellular Component GO:0032589 neuron projection membrane 4.76E-14 5.30E-11 1.29E-12 9.82E-12 33 49 "SLC12A5,ADORA1,ADORA2A,UNC5A,ANK1,ATP2B1,HCN2,SGCE,CACNA1D,AKAP5,CNTNAP2,GABBR1,GABRA2,GABRG2,GPER1,GRIA1,GRIN1,HPCA,KCNB1,KCNC1,KCNC2,KCNH1,KCNJ11,HCN1,PALM,ROBO1,ROBO2,WLS,SLC1A2,DDN,EPB41L3,MAPK8IP3,LAMP5" GO: Cellular Component GO:0005887 integral component of plasma membrane 1.18E-13 1.31E-10 3.12E-12 2.37E-11 414 1651 "KCNH8,ASIC2,ASIC1,ABHD6,ADCY2,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADORA3,ESYT2,ADRA1D,ADRA1B,ADRB2,NLGN4X,SLC24A4,KIAA1324,C1QTNF1,SEMA6A,ALCAM,PCDH10,ALK,KCNT1,SYT13,DPP10,CNIH2,CNTNAP1,KCNAB2,APP,LGR5,AQP4,AQP6,SLC7A14,IGDCC4,ASGR1,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CADM3,ADAM23,ADGRB1,HCN2,PROM1,BMPR1B,ST3GAL5,SGCE,C5,CACNA1D,DDR1,CACNB2,CALM1,SLC25A14,RHBDL1,SHISA7,CCKBR,SLC5A11,SLC16A4,P2RX6,SCARB1,CD81,DCLK1,ADGRG1,ASIC3,CHRM1,CHRM4,CHRNA4,CHRNB2,JAM2,SLC22A6,DLGAP3,NRXN3,NRXN1,SLC24A2,FADS2,CNGA3,CNR1,CNTFR,SLC4A7,SLC4A8,GAL3ST1,IGDCC3,NECTIN3,SLC32A1,ABCG1,TENM4,CSF1R,CSF2RA,CSF3R,CNTNAP2,PLXNA4,CALY,CX3CR1,NOS1AP,CYBB,BOC,SIRPA,CNIH3,TMEM130,PLPPR4,DLG2,DLG3,DLG4,GRIN3A,CDON,SHANK1,SLC12A6,DPP6,DRD1,DSCAM,ABCC5,ABCC9,TSPAN5,EDNRA,EDNRB,CACNG7,EFNA3,EFNB3,APH1A,PLXNC1,TENM1,CALCRL,EPHA5,EPHB1,KCNMB2,SLC43A2,EPS8,IGSF6,CDHR1,TLR7,SIRPB1,NRN1,REEP2,CACNG3,CACNG2,PTK2B,OLFM1,FGFR1,FGFR3,SEMA6C,SEMA4D,ATP13A4,FLT1,FOLH1,SORBS1,HVCN1,ATP2C1,CSPG5,NRG3,GABBR1,GABRA1,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GALR1,NEU3,GHR,LYVE1,GLRB,GPR75,PCDH11X,KCNMB4,GP1BB,PRLHR,GPR12,GPR17,GPR19,GPR22,LPAR4,MCHR1,GPER1,GPR34,GPR37,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,BTN2A1,MFSD2A,SLC2A6,HAS2,PTGDR2,HRH3,NCKAP1L,CPT1C,SHISA6,HTR2A,HTR5A,IL6R,IL6ST,IL11RA,SLC6A17,ITGA7,ITGAM,ITGAV,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNQ2,KCNQ3,KLRC2,STXBP5,KTN1,LIFR,MMP16,MMP17,CD200,MPP2,MSR1,HNRNPM,P2RY13,NCF2,SLCO1C1,NINJ2,SLC11A2,NRCAM,HCN1,NTRK2,NTRK3,DDR2,GPR88,OLR1,OPRL1,CLDN11,OXTR,P2RX7,P2RY1,KCNK10,PALM,PCDHGC3,PCDH8,PCDH9,PDGFRA,ENPP2,SLC10A4,GPR85,BEST3,NLGN3,PKD1,FXYD1,PCDH18,PLXNB1,PLXNB3,TRHDE,LRP12,PILRA,SLC26A11,SLC22A23,PTAFR,PTCH1,PLPPR1,PTH1R,PTPRB,PTPRD,PTPRG,PTPRH,PTPRN2,PTPRO,PTPRZ1,SLC6A15,RET,RGR,ROBO1,ROM1,EPHA10,LGR4,PLPPR3,SYNDIG1,KCNIP3,KCNIP2,KCNIP1,RYR1,SEMA6D,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,ASIC4,IL17RB,SELL,NLGN4Y,NLGN1,SLC1A2,SLC4A3,SLC1A6,SLC2A5,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC11A1,SHANK2,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SNAP25,SCN3B,SSTR1,SSTR2,APOM,STX1A,SYT11,ABCC8,VAMP1,TMEM150C,SYPL1,TACR1,CNTN2,ADGRL3,VWC2,PCDHB15,SLC19A3,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,TEK,ATP13A2,TGFBR3,HHIP,TIE1,ICAM5,TLR4,TNFRSF1B,TRO,TRPC1,TRPC3,TRPM2,NTSR2,KCNE5,CADM1,FLRT2,FLRT1,PLPPR2,VIPR2,BEST1,TSPAN11,P2RY12,PORCN,SLC13A3,KCNK12,KCNT2,PLPP4,SLC26A10,PLPPR5,SLC30A3,CADM2,SLC38A1,KCNAB1,SLC39A12,SSPN,SLC4A10" GO: Cellular Component GO:0008076 voltage-gated potassium channel complex 1.56E-13 1.74E-10 4.04E-12 3.07E-11 48 92 "KCNT1,DPP10,CNTNAP1,KCNAB2,HCN2,CALM1,CNTNAP2,NOS1AP,DLG2,DLG4,DPP6,ABCC9,KCNMB2,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,KCNIP3,KCNIP2,KCNIP1,SNAP25,STX1A,ABCC8,CNTN2,KCNE5,KCNT2,KCNAB1" GO: Cellular Component GO:0098797 plasma membrane protein complex 2.21E-13 2.46E-10 5.58E-12 4.24E-11 165 532 "ABHD6,AP2A1,AP2A2,ALCAM,KCNT1,DPP10,CNIH2,CNTNAP1,KCNAB2,APC,ARRB1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,RIPK1,AZGP1,RGS11,RGS9,HCN2,CFLAR,BMPR1B,SYNJ1,SGCE,CACNA1I,CACNA1G,C5,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,SHISA7,CDH2,CACNA2D2,CHRNA4,CHRNB2,DLGAP3,EPS15L1,CLTA,CLTB,CLTC,CNTFR,RGS6,CNTNAP2,CTNND1,NOS1AP,CYBB,TBC1D5,CNIH3,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,SHANK1,DPP6,DTNA,ABCC9,CACNG7,EGFR,TNK2,KCNMB2,EPS8,APC2,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,SGIP1,SORBS1,GABBR1,GJB1,GLRB,KCNMB4,GNAL,GNAO1,GNAS,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,CPT1C,SHISA6,IGF1,IL6R,IL6ST,ITGA7,ITGAM,ITGAV,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,STXBP5,NCF2,NOS1,SNTG1,PDE4B,PDE4D,GNG2,FXYD1,RGS7,KCNIP3,KCNIP2,KCNIP1,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,NLGN1,SHANK2,SNAP25,SCN3B,STX1A,ABCC8,CNTN2,VWC2,TF,TGFBR3,KCNE5,PORCN,KCNT2,KCNAB1,GJC2,SSPN" GO: Cellular Component GO:0034705 potassium channel complex 2.66E-13 2.96E-10 6.58E-12 5.00E-11 48 93 "KCNT1,DPP10,CNTNAP1,KCNAB2,HCN2,CALM1,CNTNAP2,NOS1AP,DLG2,DLG4,DPP6,ABCC9,KCNMB2,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,KCNIP3,KCNIP2,KCNIP1,SNAP25,STX1A,ABCC8,CNTN2,KCNE5,KCNT2,KCNAB1" GO: Cellular Component GO:0030133 transport vesicle 2.78E-13 3.09E-10 6.72E-12 5.10E-11 126 374 "SYN3,AP2A1,SYT13,DOC2A,AMPH,BIN1,CNIH2,APBA2,APP,AQP6,MADD,ATP6V1G2,MTMR2,IL33,CA4,HAP1,SYT6,SYNGR3,DGKI,COPB2,CBARP,CHGA,SYNPR,RAB3C,CLCN3,CLTA,CLTB,CLTC,RAB26,AKAP7,MYRIP,SEC31B,SLC32A1,SNCAIP,SEC24C,NRSN1,DBI,CNIH3,BLOC1S6,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM1L,COPS4,RABEPK,STX2,NCALD,F5,F8,SEC24B,FGFR3,SEC23B,VTI1B,SYT3,ATP2C1,BRSK1,GABBR1,GABRA2,GALNT15,GAD2,SYT17,DISC1,GNAS,PCLO,GRIA1,GRIA2,GRIN1,ICA1,MYLK2,IGF1,SLC6A17,STXBP5,SYTL4,SYT9,SCAMP5,MT3,SCG3,MYO5A,NPTX1,NRGN,PCSK1,PCSK2,PDE4B,SYTL2,PTPRN,PTPRN2,RAB3A,LRRK2,STX1B,AP1AR,COPZ1,SEC31A,RPH3A,LGI3,SNAP25,SNCA,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,AZIN2,ATP13A2,SPX,CADM1,VGF,TRIM9,SLC30A3,MFF,LMAN2L,SLC17A7,TMEM163,SLC17A6,GOPC,VANGL2,SSPN" GO: Cellular Component GO:0099501 exocytic vesicle membrane 8.21E-12 9.14E-09 1.91E-10 1.45E-09 35 61 "SYN3,DOC2A,AMPH,SYT6,SYNGR3,CBARP,SYNPR,SLC32A1,SV2B,SV2A,DNM1L,GAD2,GRIA2,ICA1,SLC6A17,SYT9,SCAMP5,PTPRN2,LRRK2,RPH3A,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYT1,SYT4,SYT5,DMXL2,SLC30A3,SLC17A7,TMEM163,SLC17A6" GO: Cellular Component GO:0030672 synaptic vesicle membrane 8.21E-12 9.14E-09 1.91E-10 1.45E-09 35 61 "SYN3,DOC2A,AMPH,SYT6,SYNGR3,CBARP,SYNPR,SLC32A1,SV2B,SV2A,DNM1L,GAD2,GRIA2,ICA1,SLC6A17,SYT9,SCAMP5,PTPRN2,LRRK2,RPH3A,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYT1,SYT4,SYT5,DMXL2,SLC30A3,SLC17A7,TMEM163,SLC17A6" GO: Cellular Component GO:0031253 cell projection membrane 1.25E-11 1.39E-08 2.83E-10 2.15E-09 111 332 "TTYH1,ADCY6,SLC12A5,FZD9,ADORA1,ADORA2A,UNC5A,ANK1,FGD2,APC,EPB41L5,AQP4,CASK,ATP2B1,BBS2,RGS9,HCN2,PROM1,SYNJ2,SGCE,CA4,CACNA1D,SCARB1,ENTPD2,ARHGEF2,CLTB,CNGA3,WHRN,AKAP5,CNTNAP2,ARHGEF4,RIPOR2,AIF1L,DMD,DNM2,DRD1,PLEKHA1,PLEKHO1,MFSD10,DMTN,RASGRP2,EPS8,CDHR1,APC2,ADGRV1,SH3YL1,DLC1,FGR,GABBR1,GABRA2,GABRG2,NCKAP1,GAP43,INPP5K,FERMT2,MCHR1,GPER1,GRK4,GRIA1,GRIN1,BVES,PACSIN2,HPCA,HSP90AA1,ITGAV,KCNA2,KCNB1,KCNC1,KCNC2,KCNH1,KCNJ11,KCNK1,MTTP,MYO6,SLC11A2,HCN1,SNTG1,PALM,PDE4A,ABCB1,PKD1,PACSIN1,PRKCB,PRPH,PTCH1,PTH1R,PTPRZ1,TMEM231,ROBO1,KIRREL1,ROBO2,ROM1,WLS,FERMT1,SLC1A2,SHANK2,SLCO1A2,DDN,CLASP2,EPB41L3,MAPK8IP3,KANK1,SYNE2,WWC1,GPR161,HHIP,TIAM1,TPM1,NDRG4,LAMP5,SPATA13" GO: Cellular Component GO:0043195 terminal bouton 2.24E-11 2.50E-08 4.99E-10 3.79E-09 51 112 "ADORA1,AMPH,APP,ATP6V0A1,SYNJ1,CALB1,CALB2,CCK,CLTC,ERC2,SNAP91,SV2B,SV2A,DPYSL2,SGIP1,GABRB3,CPLX2,CPLX1,PCLO,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM7,MYLK2,KCNC2,KCNMA1,L1CAM,NPY,NTRK2,OPHN1,EPN1,PACSIN1,POLG,PTPRN2,RAB3A,LRRK2,ITSN1,SNAP25,SNCB,SNCA,STXBP1,VAMP1,SYN1,SYN2,SYP,SYT1" GO: Cellular Component GO:0043204 perikaryon 6.55E-11 7.29E-08 1.43E-09 1.09E-08 59 142 "SLC12A5,SHTN1,CPNE5,CACNA1A,CACNA1E,NGB,CAMK2B,CCK,NEURL1,CPNE6,CNGA3,CRHBP,CNTNAP2,CTNND2,DRP2,EFNA2,ENO2,RACK1,OLFM1,GLUL,GRIA2,GRIK2,GRIK3,GRIK4,GRIK5,PTPN5,SYNPO,HPCA,HTR5A,KCNA1,KCNA2,KCNB1,KCNC2,KCND2,KCNK1,NEFH,NELL2,NPY,NTRK2,PCSK2,PDPK1,PENK,PPP5C,MAPK8,MAPK9,MAPK10,RELN,PTPRN,TTLL7,TMEM100,LRRK2,SLC8A2,SLC8A3,SIRT2,DDN,AZIN2,NTSR2,RBFOX3,KCNAB1" GO: Cellular Component GO:0043198 dendritic shaft 1.53E-10 1.70E-07 3.26E-09 2.48E-08 33 60 "ASIC1,SLC12A5,CNIH2,APP,HCN2,CACNA1B,ARHGEF2,WHRN,AKAP5,DBN1,CNIH3,DLG3,DRD1,SEZ6,STAU2,GABBR1,JPH4,KIRREL3,GPER1,GRIA1,GRIA2,GRM5,GRM7,HTR2A,MAP2,HCN1,KIRREL1,SYNDIG1,NLGN1,SLC1A2,SLC8A1,ZMYND8,NTSR2" GO: Cellular Component GO:0099568 cytoplasmic region 4.16E-10 4.63E-07 8.73E-09 6.63E-08 105 325 "ACTN1,ACTN2,ADD3,AXIN2,ERMN,OSBPL8,PDZD4,ANK1,APC,SHROOM2,SPTBN4,RGS20,PLA2G4C,ASPH,KIF1A,DST,ARHGEF7,BSN,HAP1,CAMK2A,CANX,USP2,SEPT7,CDH2,CABP1,MYRIP,AKAP12,MYADM,ARHGAP32,DBN1,BLOC1S6,PARD6A,DLG4,WDPCP,FRY,EPB41,EPB41L2,DMTN,MTSS1L,EPS8,PTK2B,DLC1,FER,FGF1,GAD1,SEPT9,GCK,FERMT2,GRK4,PCLO,GRIA2,GRIK2,GRIK3,GRM7,GSN,KIF3A,HNRNPK,HPCA,SCIN,MKLN1,DBNL,BLOC1S2,MYO6,MYO7A,NUMA1,OPA1,ANLN,GPSM2,PRKCZ,MAPK8,PTK2,RDX,RIC8B,LRRK2,WLS,RYR1,PPP1R9A,SNCA,FNBP1,ZHX3,SPTAN1,SPTB,KIF1B,CLASP2,STOX1,PHLDB1,ARHGEF9,COBL,EXOC7,PDLIM2,CLASP1,FRYL,TMOD1,PARD3,TPM3,TPM4,TSC1,UCHL1,PLEKHH2,WIPF1,FMN2,SPIRE1,KCNAB1,WIPF2,AP3B2" GO: Cellular Component GO:0043235 receptor complex 5.82E-10 6.47E-07 1.20E-08 9.10E-08 108 339 "ABHD6,ADCYAP1R1,ADRB2,KCTD16,ALCAM,CNIH2,APP,CAPRIN2,RIPK1,NRP2,BMPR1B,DDR1,SHISA7,GPR37L1,CHRNA4,CHRNB2,TAOK2,DLGAP3,CNTFR,PLXNA4,SLITRK5,NOS1AP,KCTD8,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,CACNG7,GPR61,EGFR,PLXNC1,EPS8,ERBB2,ERBB4,TLR7,ADGRV1,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,FGFR1,FLT1,SORBS1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GFRA1,GHR,GPR37,GRIA1,GRIA2,GRIA4,RFFL,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM7,CPT1C,SHISA6,IL6R,IL6ST,ITGA7,ITGAM,ITGAV,OLFM3,GPR62,KCNK1,KLRC2,STXBP5,LIFR,LRP1B,MTTP,NTRK2,NTRK3,OLR1,PLXNB1,PLXNB3,PTH1R,PTPRB,PTPRN2,RET,RXRA,LRRTM4,NLGN1,SHANK2,VWC2,TF,TGFBR3,TLR4,TRPC1,VLDLR,PORCN,LRP8" GO: Cellular Component GO:0012506 vesicle membrane 6.92E-10 7.70E-07 1.40E-08 1.06E-07 154 535 "SYN3,ACTN1,AP2A1,AP2A2,AP1B1,DISP3,DOC2A,AMPH,CNIH2,ANXA7,AQP6,ARRB1,CADPS,MARCH3,ATP2A2,ATP6V0A1,SYNJ1,AP1M1,CA4,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SYT6,HIP1R,SCARB1,SYNGR3,COPB2,CBARP,CHGA,SYNPR,TAOK2,CLCN3,CLTA,CLTB,CLTC,RAB26,PICK1,MYRIP,SEC31B,SLC32A1,SEC24C,CALY,APPL1,ECE2,CYBB,TBC1D5,DCT,CNIH3,SNAP91,SV2B,SV2A,DLG4,DNM2,DNM1L,EGFR,TNK2,MFSD10,RAB9B,NCALD,CLVS1,CACNG3,CACNG2,ATP8A1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SGIP1,SYT3,NSG2,CSPG5,GAD1,GAD2,GPER1,GRIA1,GRIA2,GRIA4,PACSIN2,ICA1,INPP5B,SLC6A17,CLVS2,KCNJ4,KIFC3,STXBP5,LAMP2,SYTL4,SYT9,SCAMP5,DBNL,MSR1,SCG3,MYO6,NOS1,NRGN,OCRL,ZDHHC8,CAMKV,PKD1,PACSIN1,SH3KBP1,RAB39A,PTCH1,PTPRN,PTPRN2,MARCH1,RAB3A,SNX22,LRRK2,WLS,CLIP1,COPZ1,SH3GL2,FNDC3A,SEC31A,RPH3A,EPN2,SLC11A1,SNCA,KIF1B,ATP10B,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,ATP13A2,TF,GPR161,UBC,FLRT1,VGF,WNT7A,ATP6V0E2,FMN2,SPIRE1,LAMP5,SLC30A3,SLC17A7,TMEM163,SLC17A6,GOPC,MARCH8,IFT88,AP3B2" GO: Cellular Component GO:0030659 cytoplasmic vesicle membrane 1.26E-09 1.40E-06 2.50E-08 1.90E-07 148 513 "SYN3,ACTN1,AP2A1,AP2A2,AP1B1,DISP3,DOC2A,AMPH,CNIH2,ANXA7,AQP6,ARRB1,CADPS,MARCH3,ATP6V0A1,AP1M1,CA4,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SYT6,HIP1R,SCARB1,SYNGR3,COPB2,CBARP,CHGA,SYNPR,TAOK2,CLCN3,CLTA,CLTB,CLTC,RAB26,PICK1,MYRIP,SEC31B,SLC32A1,SEC24C,CALY,ECE2,CYBB,TBC1D5,DCT,CNIH3,SNAP91,SV2B,SV2A,DLG4,DNM2,DNM1L,EGFR,TNK2,MFSD10,RAB9B,NCALD,CLVS1,CACNG3,CACNG2,ATP8A1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SGIP1,SYT3,NSG2,CSPG5,GAD1,GAD2,GPER1,GRIA1,GRIA2,GRIA4,PACSIN2,ICA1,INPP5B,SLC6A17,CLVS2,KCNJ4,KIFC3,STXBP5,LAMP2,SYTL4,SYT9,SCAMP5,DBNL,MSR1,SCG3,MYO6,NRGN,OCRL,ZDHHC8,CAMKV,PKD1,PACSIN1,SH3KBP1,RAB39A,PTCH1,PTPRN,PTPRN2,MARCH1,RAB3A,SNX22,LRRK2,WLS,CLIP1,COPZ1,SH3GL2,SEC31A,RPH3A,EPN2,SLC11A1,SNCA,KIF1B,ATP10B,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,TF,GPR161,UBC,FLRT1,VGF,WNT7A,ATP6V0E2,FMN2,SPIRE1,LAMP5,SLC30A3,SLC17A7,TMEM163,SLC17A6,GOPC,MARCH8,IFT88,AP3B2" GO: Cellular Component GO:0030658 transport vesicle membrane 3.10E-09 3.45E-06 6.06E-08 4.60E-07 60 158 "SYN3,AP2A1,DOC2A,AMPH,CNIH2,AQP6,CA4,SYT6,SYNGR3,CBARP,CHGA,SYNPR,CLCN3,CLTA,CLTB,CLTC,RAB26,SEC31B,SLC32A1,SEC24C,CNIH3,SV2B,SV2A,DNM1L,NCALD,SEC24B,SEC23B,VTI1B,SYT3,GAD2,GRIA1,GRIA2,ICA1,SLC6A17,SYTL4,SYT9,SCAMP5,SCG3,NRGN,PTPRN,PTPRN2,RAB3A,LRRK2,SEC31A,RPH3A,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYT1,SYT4,SYT5,DMXL2,SLC30A3,SLC17A7,TMEM163,SLC17A6" GO: Cellular Component GO:0031410 cytoplasmic vesicle 3.99E-09 4.44E-06 7.65E-08 5.81E-07 328 1355 "CPNE2,SERPINA3,SYN3,ACTN1,ACTN2,PLEKHG5,ADD2,AXIN2,TEX22,AP2A1,AP2A2,AP1B1,DISP3,ADGRF5,SYT13,DOC2A,AMPH,BIN1,OGT,CNIH2,ANXA7,APBA2,DGKD,APP,AQP6,MADD,ARHGDIG,ARRB1,RGS20,ARRB2,CADPS,MARCH3,NUMB,ATM,ATP1A1,ATP1B3,ATP6V1G2,ATP6V0A1,ADAM15,MPDZ,DST,BTK,MTMR2,AP1M1,RAB29,IL33,CA4,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,SYT6,HIP1R,SPAG9,SCARB1,SYNGR3,DGKI,LRBA,ARHGEF2,CDC42,COPB2,RCBTB2,CBARP,CHGA,CHGB,SYNPR,RAB3C,TAOK2,CPNE6,CLCN3,NRXN1,CLU,TPP1,STOML1,CLTA,CLTB,CLTC,RAB26,PICK1,AKAP7,SLC4A7,MYRIP,SEC31B,ENTPD4,CRHBP,SLC32A1,SNCAIP,SEC24C,CALY,NRSN1,USP6NL,ECE2,CYBB,TBC1D5,IST1,DBI,DCT,CNIH3,RUSC2,BLOC1S6,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM2,PDCD6IP,ARRDC4,DNM1L,EDN1,OPTN,SH3GLB1,EGFR,COPS4,TNK2,TMEM35A,MFSD10,DMTN,RABEPK,STX2,RAB9B,ERBB2,NCALD,TMEM74,TLR7,F5,F8,CLVS1,CACNG3,CACNG2,ATP8A1,FCGR1A,FCGR1B,SEC24B,FGFR1,FGFR3,BAIAP2,AMOTL2,SEC23B,VTI1B,ANKFY1,SGIP1,SYT3,AKAP3,POMT1,ATP2C1,NSG2,CSPG5,BRSK1,GABBR1,GABRA2,GALNT15,GAD1,GAD2,RAPGEF6,SYT17,DISC1,GCK,CRCP,PCSK1N,GNAS,GPER1,PCLO,GRIA1,GRIA2,GRIA4,RFFL,SPACA9,GRIN1,HBA1,PACSIN2,GABARAPL2,HP,AGFG1,HSP90AA1,HTR2A,ICA1,MYLK2,IGF1,INPP5B,SLC6A17,ITGAV,KCNA1,CLVS2,KCNJ4,KCNK1,KIFC3,KIT,KLC1,STXBP5,LAMP2,SYTL4,SYT9,CHIC1,SCAMP5,DBNL,MSR1,MT3,SCG3,MYO5A,MYO6,MYO7A,NAP1L1,NCF2,NOS1,NPTX1,SLC11A2,NRGN,NUCB1,TBC1D25,OCRL,OPRL1,PALM,PCSK1,PCSK5,PCSK2,PDE4B,PDPK1,ZDHHC8,NLGN3,SERPINE2,CAMKV,PIK3C2A,PKD1,ZFYVE21,MAPKAP1,PACSIN1,SH3KBP1,RAB39A,SYTL2,PTCH1,PTPRN,PTPRN2,MARCH1,RAB3A,RAB5B,SH3TC2,SNX22,MAP6D1,LRRK2,WLS,CLIP1,STX1B,AP1AR,SCN8A,COPZ1,SCG5,ITSN1,SH3GL2,AMBRA1,FNDC3A,SYBU,SEC31A,RPH3A,EPN2,CCDC88A,SLC11A1,LGI3,CXXC4,SNAP25,SNCA,LMBRD1,FNBP1,ENKUR,KIF1B,ATP10B,FCHO1,MAPK8IP3,STX1A,GANAB,STXBP1,ACSBG1,SYT11,MLC1,ABCC8,VAMP1,VPS13A,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,AZIN2,ATP13A2,TF,SPX,LEFTY2,GPR161,TRH,RUSC1,SGK3,UBC,CADM1,AMOT,FLRT1,VGF,WIPF1,CLIP2,WNT7A,TRIM9,ATP6V0E2,FMN2,TMEM198,SPIRE1,LAMP5,SLC30A3,SLC30A4,MFF,LMAN2L,SCG2,HPS4,SLC17A7,TMEM163,PLD4,SLC17A6,GOPC,MARCH8,VANGL2,SSPN,IFT88,AP3B2" GO: Cellular Component GO:0097708 intracellular vesicle 4.72E-09 5.25E-06 8.90E-08 6.76E-07 328 1357 "CPNE2,SERPINA3,SYN3,ACTN1,ACTN2,PLEKHG5,ADD2,AXIN2,TEX22,AP2A1,AP2A2,AP1B1,DISP3,ADGRF5,SYT13,DOC2A,AMPH,BIN1,OGT,CNIH2,ANXA7,APBA2,DGKD,APP,AQP6,MADD,ARHGDIG,ARRB1,RGS20,ARRB2,CADPS,MARCH3,NUMB,ATM,ATP1A1,ATP1B3,ATP6V1G2,ATP6V0A1,ADAM15,MPDZ,DST,BTK,MTMR2,AP1M1,RAB29,IL33,CA4,HAP1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,SYT6,HIP1R,SPAG9,SCARB1,SYNGR3,DGKI,LRBA,ARHGEF2,CDC42,COPB2,RCBTB2,CBARP,CHGA,CHGB,SYNPR,RAB3C,TAOK2,CPNE6,CLCN3,NRXN1,CLU,TPP1,STOML1,CLTA,CLTB,CLTC,RAB26,PICK1,AKAP7,SLC4A7,MYRIP,SEC31B,ENTPD4,CRHBP,SLC32A1,SNCAIP,SEC24C,CALY,NRSN1,USP6NL,ECE2,CYBB,TBC1D5,IST1,DBI,DCT,CNIH3,RUSC2,BLOC1S6,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM2,PDCD6IP,ARRDC4,DNM1L,EDN1,OPTN,SH3GLB1,EGFR,COPS4,TNK2,TMEM35A,MFSD10,DMTN,RABEPK,STX2,RAB9B,ERBB2,NCALD,TMEM74,TLR7,F5,F8,CLVS1,CACNG3,CACNG2,ATP8A1,FCGR1A,FCGR1B,SEC24B,FGFR1,FGFR3,BAIAP2,AMOTL2,SEC23B,VTI1B,ANKFY1,SGIP1,SYT3,AKAP3,POMT1,ATP2C1,NSG2,CSPG5,BRSK1,GABBR1,GABRA2,GALNT15,GAD1,GAD2,RAPGEF6,SYT17,DISC1,GCK,CRCP,PCSK1N,GNAS,GPER1,PCLO,GRIA1,GRIA2,GRIA4,RFFL,SPACA9,GRIN1,HBA1,PACSIN2,GABARAPL2,HP,AGFG1,HSP90AA1,HTR2A,ICA1,MYLK2,IGF1,INPP5B,SLC6A17,ITGAV,KCNA1,CLVS2,KCNJ4,KCNK1,KIFC3,KIT,KLC1,STXBP5,LAMP2,SYTL4,SYT9,CHIC1,SCAMP5,DBNL,MSR1,MT3,SCG3,MYO5A,MYO6,MYO7A,NAP1L1,NCF2,NOS1,NPTX1,SLC11A2,NRGN,NUCB1,TBC1D25,OCRL,OPRL1,PALM,PCSK1,PCSK5,PCSK2,PDE4B,PDPK1,ZDHHC8,NLGN3,SERPINE2,CAMKV,PIK3C2A,PKD1,ZFYVE21,MAPKAP1,PACSIN1,SH3KBP1,RAB39A,SYTL2,PTCH1,PTPRN,PTPRN2,MARCH1,RAB3A,RAB5B,SH3TC2,SNX22,MAP6D1,LRRK2,WLS,CLIP1,STX1B,AP1AR,SCN8A,COPZ1,SCG5,ITSN1,SH3GL2,AMBRA1,FNDC3A,SYBU,SEC31A,RPH3A,EPN2,CCDC88A,SLC11A1,LGI3,CXXC4,SNAP25,SNCA,LMBRD1,FNBP1,ENKUR,KIF1B,ATP10B,FCHO1,MAPK8IP3,STX1A,GANAB,STXBP1,ACSBG1,SYT11,MLC1,ABCC8,VAMP1,VPS13A,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,AZIN2,ATP13A2,TF,SPX,LEFTY2,GPR161,TRH,RUSC1,SGK3,UBC,CADM1,AMOT,FLRT1,VGF,WIPF1,CLIP2,WNT7A,TRIM9,ATP6V0E2,FMN2,TMEM198,SPIRE1,LAMP5,SLC30A3,SLC30A4,MFF,LMAN2L,SCG2,HPS4,SLC17A7,TMEM163,PLD4,SLC17A6,GOPC,MARCH8,VANGL2,SSPN,IFT88,AP3B2" GO: Cellular Component GO:0032281 AMPA glutamate receptor complex 6.55E-09 7.29E-06 1.22E-07 9.23E-07 20 30 "ABHD6,CNIH2,SHISA7,CNIH3,DLG3,DLG4,CACNG7,NRN1,CACNG3,CACNG2,OLFM1,GRIA1,GRIA2,GRIA4,CPT1C,SHISA6,OLFM3,LRRTM4,VWC2,PORCN" GO: Cellular Component GO:0043194 axon initial segment 1.37E-08 1.52E-05 2.49E-07 1.89E-06 12 13 "LRRC7,BIN1,ANK3,SPTBN4,CAMK2D,CCK,KCNQ2,KCNQ3,NRCAM,SCN2A,SCN8A,NFASC" GO: Cellular Component GO:0005938 cell cortex 1.50E-08 1.66E-05 2.68E-07 2.04E-06 86 266 "ACTN1,ACTN2,ADD3,AXIN2,ERMN,OSBPL8,PDZD4,ANK1,APC,SHROOM2,SPTBN4,RGS20,PLA2G4C,ASPH,DST,ARHGEF7,BSN,USP2,SEPT7,CDH2,CABP1,MYRIP,AKAP12,MYADM,ARHGAP32,DBN1,PARD6A,DLG4,WDPCP,FRY,EPB41,EPB41L2,DMTN,MTSS1L,EPS8,PTK2B,DLC1,FER,FGF1,GAD1,SEPT9,GCK,FERMT2,GRK4,PCLO,GRM7,GSN,HNRNPK,SCIN,MKLN1,DBNL,MYO6,MYO7A,NUMA1,ANLN,GPSM2,PRKCZ,PTK2,RDX,RIC8B,RYR1,PPP1R9A,SNCA,FNBP1,ZHX3,SPTAN1,SPTB,CLASP2,STOX1,PHLDB1,ARHGEF9,COBL,EXOC7,PDLIM2,CLASP1,FRYL,TMOD1,PARD3,TPM3,TPM4,TSC1,PLEKHH2,WIPF1,FMN2,SPIRE1,WIPF2" GO: Cellular Component GO:0030315 T-tubule 2.01E-08 2.24E-05 3.56E-07 2.70E-06 30 60 "ADRA1B,BIN1,ANK2,ANK3,AQP4,ATP1A1,ATP1A2,CACNA1D,CACNA2D1,CACNB2,CAMK2D,CAPN3,CDH2,CLTC,AKAP7,AKAP6,NOS1AP,ABCC9,EDNRA,KCND2,KCNJ3,KCNJ5,KCNJ11,KCNN2,NOS1,PPP3CB,RDX,RYR1,SCN2A,SLC8A1" GO: Cellular Component GO:0042383 sarcolemma 3.56E-08 3.96E-05 6.18E-07 4.70E-06 56 152 "ADCY5,ADCY6,ADRA1B,ADRB2,BIN1,ANK1,ANK2,ANK3,AQP4,ATP1A1,ATP1A2,ATP1A3,SGCE,CA4,CACNA1D,CACNA2D1,CACNB2,CAMK2D,CAPN3,CDH2,CHRM4,CLTC,AKAP7,AKAP6,NOS1AP,DMD,DTNA,ABCC9,EDNRA,FLNC,GNAS,BVES,ITGA7,KCNB1,KCND2,KCND3,KCNJ3,KCNJ5,KCNJ11,KCNN2,LAMA2,NOS1,PLEC,FXYD1,PPP3CA,PPP3CB,PTK2,RDX,RYR1,SCN2A,SLC2A5,SLC8A1,SLC8A3,ABCC8,SYNC,SSPN" GO: Cellular Component GO:0048471 perinuclear region of cytoplasm 3.93E-08 4.37E-05 6.73E-07 5.11E-06 189 724 "ACHE,NDRG2,PLEKHG5,ADD1,HHATL,FZD9,OSBPL6,PKP4,APBB1,APLP1,APP,SHTN1,STK33,STX16,ATP2A2,CDK5R1,SYNJ2,BTK,CACNA1G,RAB29,MMD2,CA4,CABP7,KALRN,HAP1,CAMK2D,SYT6,BRSK2,HIP1R,SPAG9,MAP7,USP2,AIFM1,NEURL1,DGKI,CHGA,RAB3C,CLU,PICK1,AKAP6,CABP1,AKAP5,MYRIP,NCOR1,AATK,CSF1,SEC24C,OSBPL3,CST3,PPP1R16B,PNPLA8,CX3CR1,NOS1AP,CYBB,CTIF,DBI,HEPH,FBXL5,MAGI2,NTM,CALN1,DYNC1I1,DNM2,ATN1,DNAJB6,ABCC5,DNM1L,OPTN,EGFR,TENM1,EML1,DMTN,SEZ6,EPHA5,ERBB2,APC2,ADGRV1,MRVI1,PTK2B,RACK1,SEC24B,FGFR1,FGFR3,SEC23B,VTI1B,GAD2,DISC1,SEPT9,INPP5K,SRCAP,MALT1,COPS8,TNRC6A,GNAS,GPER1,PCLO,CNTRL,STMN2,TPPP,GSN,MAEL,HSP90AA1,ICA1,KCND2,KCND3,KCNH1,KCNH2,KCNMA1,KIF5A,LIMS1,MAP6,MEIS2,MOBP,PTOV1,MT1M,MT3,MX1,MYO6,NELL1,NOS1,NPY,NPPA,SLC11A2,PDE2A,PDE4A,PDE4B,ZDHHC8,PIK3R1,PLEC,HMGCLL1,PACSIN1,PRKACB,PRKCG,PKN2,PRKCZ,PTCH1,PTN,TRIM68,KIRREL1,TMEM100,FBXW7,RYR3,S100B,ATXN2,CASC3,TRA2B,SGK1,AMBRA1,SEC31A,SLC8A3,SIRT2,CDK5RAP2,SNAP25,SNCA,MYO16,USP33,TNIK,TSNAXIP1,SPP1,RAP1GAP2,NXT2,MLC1,COBL,SYT4,SYT5,WWC1,AZIN2,SYNE1,OBSL1,PUM2,TEK,TF,MTMR14,TLR4,TNFRSF1B,TP53BP2,TPD52,TPD52L2,TSC1,TSC2,FLRT1,VLDLR,FMN2,SPIRE1,SYNC,GDPD5,ITM2C,SLC39A12,FXR1" GO: Cellular Component GO:0060077 inhibitory synapse 4.56E-08 5.08E-05 7.69E-07 5.84E-06 15 20 "BSN,CLCN3,SLC32A1,GPHN,NPTN,GABRA2,GABRB3,GABRG2,GAD1,GAD2,PCLO,NLGN3,IQSEC3,IGSF9B,SYT11" GO: Cellular Component GO:0044224 juxtaparanode region of axon 4.92E-08 5.48E-05 8.17E-07 6.20E-06 10 10 "KCNAB2,CNTNAP2,DLG2,DLG4,KCNA1,KCNA2,SIRT2,EPB41L3,CNTN2,KCNAB1" GO: Cellular Component GO:0043209 myelin sheath 8.33E-08 9.27E-05 1.36E-06 1.04E-05 68 202 "ERMN,CNTNAP1,PRX,ATP1A1,ATP1A2,ATP1A3,MPDZ,CANX,INA,SEPT7,CDC42,CLTC,CNTN1,CNRIP1,DNM1,DPYSL2,PDCD6IP,EEF1A2,ENO2,ERBB2,TUBA1B,TUBB4A,ATP5PD,GFAP,GLUL,GNAO1,TPPP,GSN,GSTM5,HRH3,HSP90AA1,IDH3A,KCNJ11,MAG,MBP,MOBP,MOG,TAGLN3,NCAM1,NEFH,OMG,CLDN11,PKM,PLP1,PMP2,PMP22,SEPT4,PACSIN1,PRKCZ,RDX,MYH14,SIRT2,NAPB,SNAP25,SPTAN1,NFASC,SEPT8,STXBP1,PLCB1,SYN1,SYN2,CNTN2,PARD3,UBC,UCHL1,TUBA1A,RTN4,GJC2" GO: Cellular Component GO:0032590 dendrite membrane 1.18E-07 1.31E-04 1.90E-06 1.44E-05 19 31 "SLC12A5,ATP2B1,HCN2,SGCE,CACNA1D,AKAP5,GABRA2,GABRG2,GPER1,GRIA1,GRIN1,HPCA,KCNB1,KCNC1,HCN1,PALM,WLS,DDN,LAMP5" GO: Cellular Component GO:0001726 ruffle 1.42E-07 1.57E-04 2.25E-06 1.71E-05 59 169 "ACTN1,FGD2,APC,EPB41L5,GAS7,ALS2,SYNJ2,ARHGEF7,ARHGEF2,SH2B1,ARHGEF4,MYADM,AIF1L,PARD6A,DNM2,PLEKHA1,PLEKHO1,RASGRP2,MTSS1L,EPS8,SH3YL1,DLC1,BAIAP2,FGR,INPP5K,GNAS,CIT,GSN,PACSIN2,HSP90AA1,ITGAV,MKLN1,DBNL,LAYN,MYO5A,MYO6,SNTG1,PDE4A,PACSIN1,PSD,PTPRZ1,RDX,CLIP1,S100B,FERMT1,ASAP3,PALLD,CLASP2,SAMSN1,KANK1,FGD4,COBL,WWC1,TIAM1,MTMR14,TPM1,AMOT,WIPF1,SPATA13" GO: Cellular Component GO:0044433 cytoplasmic vesicle part 1.87E-07 2.09E-04 2.90E-06 2.20E-05 163 619 "SERPINA3,SYN3,ACTN1,ACTN2,AP2A1,AP2A2,AP1B1,DISP3,DOC2A,AMPH,CNIH2,ANXA7,APP,AQP6,ARRB1,CADPS,MARCH3,ATP6V1G2,ATP6V0A1,AP1M1,CA4,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SYT6,HIP1R,SCARB1,SYNGR3,COPB2,CBARP,CHGA,SYNPR,TAOK2,CLCN3,CLU,CLTA,CLTB,CLTC,RAB26,PICK1,MYRIP,SEC31B,SLC32A1,SEC24C,CALY,ECE2,CYBB,TBC1D5,DCT,CNIH3,SNAP91,SV2B,SV2A,DLG4,DNM2,DNM1L,EGFR,TNK2,MFSD10,RAB9B,NCALD,F5,F8,CLVS1,CACNG3,CACNG2,ATP8A1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SGIP1,SYT3,NSG2,CSPG5,GABRA2,GAD1,GAD2,GPER1,GRIA1,GRIA2,GRIA4,HBA1,PACSIN2,HP,HSP90AA1,ICA1,IGF1,INPP5B,SLC6A17,CLVS2,KCNJ4,KIFC3,STXBP5,LAMP2,SYTL4,SYT9,SCAMP5,DBNL,MSR1,SCG3,MYO6,NRGN,OCRL,PCSK1,PCSK2,ZDHHC8,CAMKV,PKD1,PACSIN1,SH3KBP1,RAB39A,PTCH1,PTPRN,PTPRN2,MARCH1,RAB3A,SNX22,LRRK2,WLS,CLIP1,COPZ1,SH3GL2,SEC31A,RPH3A,EPN2,SLC11A1,SNCA,KIF1B,ATP10B,STX1A,SYT11,ABCC8,VAMP1,SYN1,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,TF,LEFTY2,GPR161,UBC,FLRT1,VGF,WNT7A,ATP6V0E2,FMN2,SPIRE1,LAMP5,SLC30A3,SLC17A7,TMEM163,SLC17A6,GOPC,MARCH8,IFT88,AP3B2" GO: Cellular Component GO:0030673 axolemma 1.90E-07 2.11E-04 2.90E-06 2.20E-05 14 19 "ADORA1,ADORA2A,ANK1,CNTNAP2,GABBR1,KCNC1,KCNC2,KCNH1,KCNJ11,ROBO1,ROBO2,SLC1A2,EPB41L3,MAPK8IP3" GO: Cellular Component GO:0005874 microtubule 1.90E-07 2.12E-04 2.90E-06 2.20E-05 120 426 "AXIN2,MTUS1,KIF6,KCNAB2,APC,SHTN1,SHROOM2,RGS20,DNAH17,DYNLL1,KIF1A,TTLL9,DST,SYNJ1,SYNJ2,CALM1,MAP7,PRC1,KRIT1,ARHGEF2,CDC27,CRHBP,NCOR1,FEZ1,KATNAL2,SNPH,KIF26A,DCTN1,CEP170,KIF19,DNM1,DNAH9,DYNC1I1,DNM2,DPYSL2,DNM1L,EML1,TUBD1,APC2,KATNAL1,REEP2,TUBA1B,TUBB3,TUBB4A,FGF13,CAMSAP1,DCTN2,STAU2,TPPP3,NEK6,IQGAP2,DISC1,SEPT9,TUBGCP4,TUBA8,DCLK2,PSRC1,EML4,TUBA1C,TPPP,SPACA9,KIF3A,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,STMN1,MAP2,MAP4,MAP6,MAPT,MID1,MT3,MYO5A,NUMA1,ODF2,JAKMIP1,FSD1,BCAS3,LRRC49,EML5,FIGN,TTLL7,TCP11L1,MAP6D1,ATAT1,CLIP1,KIF27,KIF21A,KIF16B,SYBU,WDR47,SLC8A2,SLC8A1,RADIL,SLC8A3,SIRT2,CDK5RAP3,CDK5RAP2,KIF13A,KIF21B,KIF1B,CLASP2,SS18,CAMSAP2,TBL1X,CLASP1,DNAH7,TIAM1,NEIL2,RUSC1,TUBB2A,TUBB1,CLIP2,KLC2,EML6,TUBA1A,DNAH10" GO: Cellular Component GO:0044295 axonal growth cone 1.94E-07 2.16E-04 2.92E-06 2.21E-05 18 29 "APC,SHTN1,NRXN1,AATK,BOC,DBN1,PARD6A,OLFM1,GPM6A,L1CAM,MAPT,PTCH1,SNAP25,PALLD,CLASP2,COBL,TIAM1,PARD3" GO: Cellular Component GO:0005905 clathrin-coated pit 2.64E-07 2.94E-04 3.92E-06 2.98E-05 31 69 "AP2A1,AP2A2,APP,ARRB1,ARRB2,SYNJ1,HIP1R,EPS15L1,CLTA,CLTB,CLTC,TBC1D5,SNAP91,DNM2,DNM1L,EGFR,TNK2,SGIP1,AP4B1,AP4S1,MYO6,OCRL,EPN1,LRP12,ATAT1,ITSN1,FNBP1,FCHO1,TF,AP4E1,VLDLR" GO: Cellular Component GO:0015629 actin cytoskeleton 3.96E-07 4.41E-04 5.80E-06 4.41E-05 130 476 "ACTN1,ACTN2,ADD1,ADD2,LRRC7,AMPH,BIN1,CDC42BPA,MYH7B,GAS7,SHROOM2,CASK,SPTBN4,MYOM1,DST,WASF1,LURAP1,KALRN,HAP1,MYOM2,SEPT7,ZBED1,CDH2,CFL2,MYL6B,CNN3,WHRN,MYRIP,CDC42BPB,MYADM,ARHGAP32,HDAC4,DAPK1,DAPK3,AIF1L,DBN1,DCTN1,PARD6A,DMD,DCTN4,EPB41,EPB41L2,DMTN,MTSS1L,APC2,RCSD1,CORO2B,DLC1,FER,BAIAP2,FGR,FLNC,DCTN2,SORBS1,PDLIM5,ABLIM2,FYB1,FYN,STAG2,DENND2A,IQGAP2,SEPT9,MYOZ2,GCK,TCERG1,FERMT2,CIT,GSN,SYNPO,HNRNPK,DBNL,MSRA,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,OPHN1,TMOD2,ANLN,POU6F1,PRKCZ,MAPK8,GDPD2,PTK2,RDX,MYH14,SCNN1D,PPP1R9A,FERMT1,MYO18A,FHOD3,ABLIM3,SMTN,PKNOX2,MYH15,TTC17,SNAP25,SNCA,PALLD,MYO16,SPTAN1,SPTB,MPRIP,STX1A,FGD4,ARC,COBL,PDLIM2,TEK,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,SYNPO2,TSC1,AMOT,PLEKHH2,WIPF1,FMN2,ZNF74,WIPF2,ACTR3B,VANGL2" GO: Cellular Component GO:0015630 microtubule cytoskeleton 7.28E-07 8.11E-04 1.05E-05 7.99E-05 267 1125 "NDRG2,AXIN2,CDC7,MTUS1,WDR35,PLA2G6,CEP126,KIF6,CCDC146,PKP4,KCNAB2,APC,ALS2,APP,SHTN1,SHROOM2,RGS20,DNAH17,MARK4,CAPRIN2,DYNLL1,ATM,KIF1A,TTLL9,BBS2,DST,SYNJ1,SYNJ2,CALM1,HAP1,CAMK2B,BRSK2,SPAG9,MAP7,PRC1,KRIT1,USP2,ARHGEF2,SEPT7,CDC25B,CDC27,CDC42,LRWD1,DIS3L,RAB28,CLTC,CCDC151,WHRN,RTTN,RBM39,CRHBP,CRMP1,NCOR1,FEZ1,ARHGEF10,PDE4DIP,KATNAL2,SNPH,KIF26A,KIAA0586,IST1,DNAL1,DCTN1,KIAA0753,CEP170,ALKBH8,AK5,KIF19,DNM1,DNAH9,MED12,DYNC1I1,DNM2,DPYSL2,PDCD6IP,DNM1L,FRY,EML1,DCTN4,TUBD1,ERCC2,CEP85L,APC2,KATNAL1,REEP2,TUBA1B,TUBB3,TUBB4A,CEP78,ZMYND10,FER,FGF13,MAD2L2,CAMSAP1,RGPD5,DCTN2,TACC2,SORBS1,STAU2,TPPP3,BRSK1,NEURL4,ZNF274,NEK6,IQGAP2,DISC1,SEPT9,TUBGCP4,TUBA8,SPIN1,CBX1,MAP7D2,DCLK2,PSRC1,NUDT21,EML4,TUBA1C,CNTRL,TPPP,DIDO1,SPACA9,NR3C1,KIF3A,AGBL5,CFAP126,LRRCC1,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,CAMK2N2,STMN1,SYTL4,MAP2,MAP4,MAP6,MAPT,MARK1,MBNL1,MID1,POC1B,BLOC1S2,MT3,MYO5A,CCDC13,NEK1,NFE2L2,DNHD1,NUCB1,NUMA1,ODF2,CHAMP1,PDE4B,PDE4D,OLA1,CCSER2,SNX10,GPSM2,JAKMIP1,PMS2,FSD1,PRKACB,CEP41,PRKCB,PKN2,PRKCZ,MAPK3,KLK6,BCAS3,LRRC49,CNTLN,PTK2,PXK,SPDL1,EML5,PPP2R3C,CEP97,RAD51D,RBBP6,DPF2,FIGN,TTLL7,KIF7,RIC8B,TCP11L1,RPS6KA2,MAP6D1,ATAT1,CLIP1,STX1B,ATXN7,KIF27,KIF21A,KIF16B,SHMT2,CCDC92,SYBU,DZIP1,ZNF365,PPP4R3A,WDR47,PKNOX2,SLC8A2,SLC8A1,RADIL,SLC8A3,SIRT2,CDK5RAP3,CDK5RAP2,IFT122,KIF13A,ZNF415,USP33,SPATA7,KIF21B,SP4,CLUAP1,MYCBP2,SPTAN1,KIF1B,TSPYL2,RAP1GAP2,CLASP2,STOX1,SS18,STAU1,CEP68,TTBK2,MMS19,TACC1,MTCL1,DDHD2,EXOC7,CAMSAP2,FBXW11,TBL1X,RPGRIP1L,CLASP1,SYNE1,OBSL1,DNAH7,TIAM1,ERCC6L2,PARD3,NEIL2,RUSC1,TUBB2A,TUBB1,MEAF6,CCDC14,CLIP2,WRN,KLC2,XRCC4,FMN2,POLR3H,EML6,DNALI1,LRP8,EVI5,TUBA1A,DNAH10,AAAS,IFT88,LAS1L" GO: Cellular Component GO:0044298 cell body membrane 1.35E-06 1.50E-03 1.90E-05 1.44E-04 17 29 "UNC5A,ADRB2,ATP2B1,ATP2B2,SLC4A8,CX3CR1,GABRA5,HPCA,IL6R,IL6ST,KCNA2,KCNB1,KCNC1,KCNC2,KCND2,FLRT1,CADM2" GO: Cellular Component GO:0032809 neuronal cell body membrane 1.35E-06 1.50E-03 1.90E-05 1.44E-04 17 29 "UNC5A,ADRB2,ATP2B1,ATP2B2,SLC4A8,CX3CR1,GABRA5,HPCA,IL6R,IL6ST,KCNA2,KCNB1,KCNC1,KCNC2,KCND2,FLRT1,CADM2" GO: Cellular Component GO:0005802 trans-Golgi network 1.37E-06 1.52E-03 1.90E-05 1.44E-04 68 216 "SYS1,AP1B1,KIAA1324,MARCH4,AMPH,APP,LGR5,RGS20,CHID1,STX16,AP1M1,BSN,RAB29,CA4,CABP7,AP4M1,LRBA,COG1,CLTA,CLTB,CLTC,CLIP3,USP6NL,ECE2,TRAPPC9,CALN1,DNM2,OPTN,RABEPK,CLVS1,ATP8A1,NBEA,ATP2C1,AP4B1,SYT17,ATP8A2,INPP5K,ARFIP1,RAB30,PCSK1N,GNAS,GPER1,PCLO,AP4S1,PACSIN2,TJAP1,CLVS2,SCAMP5,SLC11A2,NUCB1,OCRL,PACSIN1,MARCH1,LRRK2,WLS,ATXN2,MYO18A,SNAP25,KIF13A,FNBP1,NMNAT2,CLASP2,AZIN2,AP4E1,NTSR2,PLD4,IFT88,AP3B2" GO: Cellular Component GO:0030175 filopodium 1.38E-06 1.54E-03 1.90E-05 1.44E-04 39 102 "TTYH1,ACTN2,ERMN,FZD9,AP2A1,LRRC7,APBB1,APP,SHTN1,CDC42,AKAP5,OSBPL3,RIPOR2,DBN1,TIAM2,DMD,ABI1,ABI2,EPHB1,FGF13,BAIAP2,IQGAP2,GAP43,GPM6A,ITGAV,KCNN3,MYO5A,PALM,PTPRZ1,RDX,PPP1R9A,NLGN1,SNAP25,PALLD,FGD4,SYNE2,DNALI1,FZD3,SPATA13" GO: Cellular Component GO:0098858 actin-based cell projection 1.46E-06 1.62E-03 1.98E-05 1.50E-04 65 204 "TTYH1,ACTN2,ADCY6,ERMN,FZD9,AP2A1,LRRC7,APBB1,APP,SHTN1,BBS2,PROM1,CBR1,SCARB1,CDC42,WHRN,AKAP5,SLC4A7,OSBPL3,DOCK4,RIPOR2,DBN1,TIAM2,DMD,ABI1,USH1C,ABI2,EPHB1,EPS8,ERBB2,ADGRV1,FGF13,BAIAP2,IQGAP2,GAP43,STARD10,GPM6A,ITGAV,KCNJ10,KCNN3,MTTP,MYO5A,MYO6,MYO7A,OXTR,PALM,PDGFRA,PTPRZ1,STRC,RDX,LRRK2,PPP1R9A,NLGN1,SNAP25,PALLD,NFASC,FGD4,SYNE2,TEK,CRB1,FMN2,DNALI1,PCDH15,FZD3,SPATA13" GO: Cellular Component GO:0031984 organelle subcompartment 3.17E-06 3.53E-03 4.25E-05 3.23E-04 96 341 "SYS1,AP1B1,HACE1,KIAA1324,OSBPL8,MARCH4,AMPH,APP,LGR5,RGS20,ARSE,ASPH,CHID1,STX16,AP1M1,BSN,RAB29,CA4,CABP7,AP4M1,LRBA,B4GALT6,COG1,CLTA,CLTB,CLTC,CLIP3,USP6NL,ECE2,TRAPPC9,CALN1,DNM2,ATL1,OPTN,APH1A,GOLGA7,RABEPK,CLVS1,ATP8A1,NBEA,ATP2C1,NSG2,FUT9,AP4B1,SYT17,ATP8A2,INPP5K,ARFIP1,GGTA1P,RAB30,PCSK1N,GNAS,GOLGB1,FUT10,B4GALNT4,GPER1,PCLO,CIT,AP4S1,PACSIN2,ICA1,TJAP1,CLVS2,ZFYVE27,SCAMP5,SLC11A2,NUCB1,NUCB2,OCRL,PACSIN1,MARCH1,GAL3ST4,LRRK2,WLS,RYR1,ATXN2,SMPD3,MYO18A,ST6GAL1,ST3GAL3,RAB3GAP1,SNAP25,KIF13A,FNBP1,NMNAT2,CLASP2,SULF2,NSFL1C,DNMBP,AZIN2,AP4E1,NTSR2,GAL3ST3,PLD4,IFT88,AP3B2" GO: Cellular Component GO:0033270 paranode region of axon 4.59E-06 5.11E-03 6.08E-05 4.62E-04 11 15 "ERMN,ANK3,CNTNAP1,SPTBN4,KCNA1,MAG,SCN2A,SIRT2,SPTAN1,NFASC,EPB41L3" GO: Cellular Component GO:0016528 sarcoplasm 5.60E-06 6.23E-03 7.33E-05 5.57E-04 30 74 "ANK1,ANK3,ASPH,ATP2A2,CA4,CACNA2D1,CAMK2B,CAMK2D,CAMK2G,AKAP7,AKAP6,NOS1AP,DMPK,E2F5,MRVI1,FLNC,POMT1,JPH4,GSN,NOS1,TMEM38A,PLEC,PYGM,RYR1,RYR3,SLC8A3,SLN,SYNE2,THBS4,JPH3" GO: Cellular Component GO:0043292 contractile fiber 7.21E-06 8.03E-03 9.34E-05 7.09E-04 70 234 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,MYH7B,MYOM1,CDK5R1,DST,CACNA1D,CALM1,CAPN3,ARHGEF25,MYOM2,IGFN1,CFL2,MYL6B,PDE4DIP,CST3,NOS1AP,HDAC4,DBI,DMD,DNAJB6,ABCC9,FLNC,PDLIM5,ABLIM2,MYOZ2,FERMT2,MYLK2,KCNN2,MYBPC1,MYH3,MYH6,MYH7,MYL3,NOS1,PDE4B,TMOD2,PLEC,PPP3CA,PPP3CB,PSMA6,PYGM,RPL15,RYR1,SCN8A,FHOD3,SLC8A1,SPHKAP,MYH15,PALLD,SCN3B,SPTAN1,SYNE2,SYNE1,OBSL1,TIMP4,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,SYNPO2,TRPC1,SYNC,FXR1" GO: Cellular Component GO:0097386 glial cell projection 7.81E-06 8.70E-03 1.00E-04 7.59E-04 12 18 "APP,ADGRG1,GFAP,GLUL,GRM3,GRM5,KCNJ10,KCNK2,MT3,SCN7A,SIRT2,NFASC" GO: Cellular Component GO:0098791 Golgi subcompartment 8.21E-06 9.14E-03 1.04E-04 7.88E-04 91 326 "SYS1,AP1B1,HACE1,KIAA1324,MARCH4,AMPH,APP,LGR5,RGS20,ARSE,CHID1,STX16,AP1M1,BSN,RAB29,CA4,CABP7,AP4M1,LRBA,B4GALT6,COG1,CLTA,CLTB,CLTC,CLIP3,USP6NL,ECE2,TRAPPC9,CALN1,DNM2,ATL1,OPTN,APH1A,GOLGA7,RABEPK,CLVS1,ATP8A1,NBEA,ATP2C1,NSG2,FUT9,AP4B1,SYT17,ATP8A2,INPP5K,ARFIP1,GGTA1P,RAB30,PCSK1N,GNAS,GOLGB1,FUT10,B4GALNT4,GPER1,PCLO,CIT,AP4S1,PACSIN2,ICA1,TJAP1,CLVS2,SCAMP5,SLC11A2,NUCB1,NUCB2,OCRL,PACSIN1,MARCH1,GAL3ST4,LRRK2,WLS,ATXN2,SMPD3,MYO18A,ST6GAL1,ST3GAL3,SNAP25,KIF13A,FNBP1,NMNAT2,CLASP2,SULF2,NSFL1C,DNMBP,AZIN2,AP4E1,NTSR2,GAL3ST3,PLD4,IFT88,AP3B2" GO: Cellular Component GO:0019898 extrinsic component of membrane 8.44E-06 9.40E-03 1.06E-04 8.02E-04 80 278 "SNX30,ESYT2,SNX32,KCNAB2,APC,EPB41L5,ARRB1,NUMB,ATP2A2,RGS11,RGS9,SYNJ2,BTK,MTMR3,BSN,SYT6,CDH2,NMT2,CNTFR,RGS6,BLOC1S6,DLG4,DTNA,SYT15,TNK2,EPB41,EPB41L1,EPB41L2,COQ7,GPHN,APC2,PTK2B,FER,FGR,COQ5,FYN,GFRA1,GFRA2,GHR,GNAL,GNAO1,GNAS,GNG3,GNG4,FERMT2,FRMD5,PACSIN2,FRMD3,JAK1,JAK2,SYTL4,MATK,NUCB1,OLR1,OPA1,GNG2,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,SNX10,JAKMIP1,EPB41L4B,VPS13C,SYTL2,PTK2,RDX,RGS7,KCNIP1,RYR1,SCP2,RPH3A,SOX10,EPB41L3,VPS13A,MCF2L,TF,TIAM1,PIK3R5,KCNAB1" GO: Cellular Component GO:0005911 cell-cell junction 1.10E-05 1.22E-02 1.36E-04 1.03E-03 111 418 "ACTN1,PLEKHG5,ADCYAP1R1,ADD3,ADRA1B,CDC42BPA,ANK2,ANK3,PKP4,APC,APP,SHROOM2,AQP4,CASK,ATP1A1,ATP1A2,ATP2A2,CADM3,ADGRB1,MPDZ,CALB2,CAMK2D,CLDN10,KRIT1,ARHGEF2,CDC42,CDH2,MAGI1,JAM2,TJP2,ARHGEF6,AKAP6,NECTIN3,CDC42BPB,CTNND1,MYADM,DBN1,MAGI2,PARD6A,SV2A,DLG3,ABI2,STX2,FABP7,FGF13,AMOTL2,SORBS1,STARD10,IGSF5,GJB1,PARD3B,BVES,PACSIN2,SYNPO,OPALIN,TJAP1,KCNJ11,KIFC3,KIT,LIMS1,AFDN,CD200,CTNNA3,NCAM1,CLDN11,OXTR,P2RX7,PCDHGC3,PCDH9,ABCB1,PIK3R1,PMP22,EPB41L4B,SH3KBP1,CEP41,PRKCG,PKN2,PRKCZ,LAMA1,PTK2,RDX,KIRREL1,SCN2A,SCN4B,MAGI3,SLC8A1,SIRT2,PDZD2,SPTAN1,NFASC,EPB41L3,MLC1,KAZN,ADGRL3,RPGRIP1L,OBSL1,TEK,TIAM1,TJP1,PARD3,HEPACAM,CADM1,AMOT,FLRT2,FLRT1,VAV1,CADM2,WNK3,GJC2,VANGL2,FRMD6" GO: Cellular Component GO:0030016 myofibril 1.17E-05 1.30E-02 1.43E-04 1.09E-03 66 220 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,MYH7B,MYOM1,DST,CACNA1D,CALM1,CAPN3,ARHGEF25,MYOM2,IGFN1,CFL2,PDE4DIP,NOS1AP,HDAC4,DMD,DNAJB6,ABCC9,FLNC,PDLIM5,ABLIM2,MYOZ2,FERMT2,MYLK2,KCNN2,MYBPC1,MYH3,MYH6,MYH7,MYL3,NOS1,PDE4B,TMOD2,PLEC,PPP3CA,PPP3CB,PSMA6,PYGM,RPL15,RYR1,SCN8A,FHOD3,SLC8A1,SPHKAP,MYH15,PALLD,SCN3B,SPTAN1,SYNE2,SYNE1,OBSL1,TIMP4,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,SYNPO2,TRPC1,SYNC,FXR1" GO: Cellular Component GO:0099503 secretory vesicle 1.35E-05 1.51E-02 1.64E-04 1.24E-03 136 535 "SERPINA3,SYN3,ACTN1,ACTN2,TEX22,AP2A1,AP2A2,DOC2A,AMPH,BIN1,OGT,ANXA7,APBA2,APP,MADD,ATP6V1G2,ADAM15,MTMR2,CA4,HAP1,SYT6,SPAG9,SYNGR3,DGKI,CDC42,RCBTB2,CBARP,CHGA,CHGB,SYNPR,RAB3C,CLCN3,CLU,RAB26,AKAP7,MYRIP,CRHBP,SLC32A1,SNCAIP,DBI,SNAP91,SV2B,SV2A,DLG4,DNM1,DNM1L,EDN1,COPS4,STX2,F5,F8,ATP8A1,BAIAP2,VTI1B,SYT3,AKAP3,POMT1,ATP2C1,BRSK1,GABBR1,GABRA2,GAD2,SYT17,DISC1,GCK,CRCP,PCSK1N,GRIA1,GRIA2,SPACA9,GRIN1,ICA1,MYLK2,IGF1,SLC6A17,KIT,STXBP5,LAMP2,SYTL4,SYT9,SCAMP5,MT3,SCG3,MYO5A,NCF2,NOS1,PCSK1,PCSK5,PCSK2,PDE4B,SERPINE2,SYTL2,PTPRN,PTPRN2,RAB3A,LRRK2,STX1B,SCG5,FNDC3A,RPH3A,SLC11A1,LGI3,SNAP25,SNCA,ENKUR,STX1A,STXBP1,SYT11,ABCC8,VAMP1,VPS13A,SYN1,ARC,SYN2,SYP,SYPL1,SYT1,SYT4,SYT5,DMXL2,WDR7,TF,LEFTY2,TRH,CADM1,VGF,CLIP2,TRIM9,SLC30A3,MFF,SCG2,HPS4,SLC17A7,TMEM163,SLC17A6,IFT88" GO: Cellular Component GO:0098796 membrane protein complex 1.50E-05 1.67E-02 1.80E-04 1.36E-03 245 1059 "TTYH1,ABHD6,AP2A1,AP2A2,AP1B1,ALCAM,KCNT1,DPP10,CNIH2,CNTNAP1,KCNAB2,APC,ARRB1,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,STX16,ATP2A2,ATP6V1G2,ATP6V0A1,RIPK1,AZGP1,RGS11,RGS9,HCN2,BCS1L,CFLAR,BMPR1B,SYNJ1,AP1M1,SGCE,CACNA1I,CACNA1G,C5,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,SHISA7,AP4M1,CDH2,CACNA2D2,COPB2,CHRNA4,CHRNB2,DLGAP3,EPS15L1,CLTA,CLTB,CLTC,CNGA3,CNTFR,AKAP6,COX4I1,SEC31B,RGS6,SEC24C,CNTNAP2,CTNND1,NOS1AP,CYBB,TBC1D5,TOMM20,DCTN1,CNIH3,BLOC1S6,SNAP91,DLG2,DLG3,DLG4,GRIN3A,DMD,DNM1,SHANK1,DPP6,DTNA,ABCC9,CACNG7,EGFR,TNK2,KCNMB2,STX2,EPS8,NCALD,APC2,RRAGB,NRN1,CACNG3,CACNG2,PTK2B,TOMM40L,SEC24B,OLFM1,ATP5PD,SEC23B,VTI1B,ANKFY1,SGIP1,SORBS1,POMT1,ATP6V1H,AP4B1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CPLX2,CPLX1,WASHC2A,GJB1,GLRB,OS9,KCNMB4,GNAL,GNAO1,GNAS,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,CPT1C,SHISA6,IGF1,IL6R,IL6ST,ITGA7,ITGAM,ITGAV,KCNA1,KCNA2,OLFM3,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNMA1,KCNN1,KCNQ2,KCNQ3,STXBP5,TTYH2,LAMP2,SCAMP5,NCF2,NDUFA5,NOS1,SLC11A2,SNTG1,PDE4B,PDE4D,GNG2,BEST3,PIK3C2A,PIK3CD,PIK3R1,FXYD1,MAGEL2,LRRN3,PTPA,NDUFS7,RGS7,KCNIP3,KCNIP2,KCNIP1,STX1B,SCN2A,SCN2B,SCN3A,SCN4B,LRRTM4,SCN7A,SCN8A,FOXRED1,COPZ1,NLGN1,SEC31A,EPN2,SHANK2,NAPB,SNAP25,SNCA,SCN3B,EMC1,STX1A,ABCC8,VAMP1,SYN2,SYT1,CNTN2,VWC2,TF,AP4E1,TGFBR3,AKTIP,TLR4,LRRC8A,PIK3R5,KCNE5,BEST1,PORCN,KCNT2,ATP6V0E2,SNX27,KCNAB1,MVB12B,GJC2,SSPN,AP3B2" GO: Cellular Component GO:0044430 cytoskeletal part 2.57E-05 2.86E-02 3.05E-04 2.31E-03 336 1520 "ACTN1,ACTN2,NDRG2,ADD1,ADD2,AXIN2,ADORA2A,MTUS1,WDR35,PLA2G6,CEP126,KIF6,CDC42BPA,CCDC146,MYH7B,PKP4,KCNAB2,APC,GAS7,ALS2,APP,SHTN1,SHROOM2,SPTBN4,RGS20,DNAH17,MARK4,CAPRIN2,DYNLL1,ATM,MYOM1,KIF1A,TTLL9,BBS2,DST,SYNJ1,SYNJ2,LURAP1,CALM1,HAP1,CAMK2B,BRSK2,SPAG9,MAP7,PRC1,KRIT1,USP2,INA,MYOM2,ARHGEF2,SEPT7,CDC25B,CDC27,CDC42,CDH2,DLGAP2,LRWD1,DIS3L,RAB28,MYL6B,CLTC,CCDC151,WHRN,IFFO1,RTTN,CDC42BPB,RBM39,CRHBP,CRMP1,NCOR1,FEZ1,ARHGEF10,PDE4DIP,MYADM,KATNAL2,SNPH,HDAC4,KIF26A,KIAA0586,IST1,DAPK3,AIF1L,DNAL1,DBN1,DCTN1,KIAA0753,CEP170,AK5,KIF19,DNM1,DNAH9,MED12,DYNC1I1,DNM2,DPYSL2,PDCD6IP,DNM1L,FRY,EML1,DCTN4,TUBD1,EPB41,EPB41L2,DMTN,MTSS1L,ERCC2,CEP85L,APC2,RCSD1,KATNAL1,REEP2,TUBA1B,TUBB3,TUBB4A,DLC1,CEP78,ZMYND10,FGF13,MAD2L2,CAMSAP1,RGPD5,DCTN2,TACC2,SORBS1,STAU2,TPPP3,BRSK1,FYN,NEURL4,ZNF274,NEK6,IQGAP2,DISC1,SEPT9,GCK,TUBGCP4,TUBA8,GFAP,SPIN1,CBX1,DCLK2,FERMT2,PSRC1,GPER1,NUDT21,EML4,TUBA1C,CNTRL,TPPP,DIDO1,SPACA9,NR3C1,GSN,KIF3A,SYNPO,AGBL5,HNRNPK,CFAP126,LRRCC1,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,CAMK2N2,STMN1,SYTL4,MAP2,MAP4,MAP6,MAPT,MBNL1,MID1,POC1B,DBNL,BLOC1S2,MT3,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,NEFM,NEFH,CCDC13,NEK1,NFE2L2,DNHD1,NUMA1,ODF2,CHAMP1,PDE4B,PDE4D,TMOD2,OLA1,ANLN,SNX10,GPSM2,JAKMIP1,FSD1,PRKACB,CEP41,PRKCB,PKN2,PRKCZ,MAPK8,PRPH,BCAS3,LRRC49,GDPD2,CNTLN,PTK2,PXK,SPDL1,EML5,PPP2R3C,CEP97,RAD51D,RBBP6,RDX,DPF2,FIGN,TTLL7,KIF7,RIC8B,MYH14,TCP11L1,RPS6KA2,MAP6D1,ATAT1,CLIP1,STX1B,KIF27,KIF21A,PPP1R9A,FERMT1,KIF16B,MYO18A,FHOD3,CCDC92,SYBU,DZIP1,ABLIM3,ZNF365,PPP4R3A,WDR47,SLC8A2,SLC8A1,RADIL,SLC8A3,SIRT2,CDK5RAP3,SHANK2,CDK5RAP2,MYH15,IFT122,KIF13A,PALLD,MYO16,USP33,SPATA7,KIF21B,CLUAP1,SPTAN1,SPTB,KIF1B,TSPYL2,RAP1GAP2,CLASP2,STOX1,SS18,MPRIP,STAU1,CEP68,TTBK2,STX1A,COBL,MMS19,TACC1,MTCL1,DDHD2,EXOC7,CAMSAP2,PDLIM2,FBXW11,TBL1X,RPGRIP1L,CLASP1,SYNE1,OBSL1,TEK,DNAH7,TIAM1,ERCC6L2,TMOD1,PARD3,TNNT1,TPM1,TPM2,TPM3,TPM4,NEIL2,RUSC1,TSC1,TUBB2A,TUBB1,AMOT,PLEKHH2,MEAF6,CCDC14,MICAL1,WIPF1,CLIP2,WRN,KLC2,XRCC4,FMN2,POLR3H,EML6,SYNC,DNALI1,LRP8,EVI5,TUBA1A,WIPF2,DNAH10,ACTR3B,VANGL2,AAAS,IFT88,LAS1L" GO: Cellular Component GO:0017146 NMDA selective glutamate receptor complex 2.73E-05 3.04E-02 3.20E-04 2.43E-03 9 12 "DLGAP3,GRIN3A,SHANK1,EPS8,PTK2B,GRIN1,GRIN2C,GRIN2D,NLGN1" GO: Cellular Component GO:0005794 Golgi apparatus 3.05E-05 3.40E-02 3.54E-04 2.69E-03 335 1518 "ACHE,SYS1,NDRG2,GALNT16,GALNT13,AXIN2,AP2A1,AP1B1,MTUS1,HACE1,TBC1D14,KIAA1324,MARCH4,GOLGA7B,AMPH,ANK3,FGD2,C6orf89,CNIH2,APLP1,APP,LGR5,ARRB1,RGS20,ARSE,CDK13,CHID1,ATP1A1,ATP1A3,STX16,ATP2B3,B3GALT2,ATP6V0A1,ST3GAL5,AP1M1,SGCE,GPC2,BSN,RAB29,MMD2,CA4,CABP7,ENTPD6,AP4M1,LRBA,ARHGEF2,CDC42,LARGE1,COPB2,PLEKHB1,B4GALT6,NDST3,CLCN3,COG1,CLU,NMT2,CLTA,CLTB,CLTC,TMEM59L,RAB26,PICK1,CABP1,GAL3ST1,HS3ST5,PREPL,ENTPD4,CRHBP,CLIP3,ABCG1,RGS6,SEC24C,FEZ1,GALNT9,VCAN,NCAN,PDE4DIP,CNTNAP2,SDC3,PNPLA8,GPSM1,RUBCN,USP6NL,ECE2,CYBB,ARHGAP32,DBI,JAKMIP2,B3GAT3,CNIH3,TMEM130,RABGAP1L,SEC16A,RAB39B,DNM1,HS3ST4,HS3ST2,TRAPPC9,CALN1,DNM2,FAM57B,DNM1L,GOLT1B,ST8SIA3,ATL1,RASGRP1,OPTN,SH3GLB1,APH1A,EGFR,GOLGA7,TENM1,RABEPK,NCALD,APC2,RTN3,TLR7,RRAGB,F5,F8,CLVS1,FAM198B,ATP8A1,ST3GAL6,CHST15,FKTN,PRMT5,GORAB,SEC24B,FGFR3,SCARA3,SEC23B,VTI1B,NBEA,ARFGAP2,ATP2C1,ERGIC3,NSG2,ST6GALNAC3,CSPG5,NSG1,FUT9,B3GAT1,AP4B1,TVP23A,GALNT15,GAD2,B4GALNT1,SYT17,ATP8A2,INPP5K,GCNT2,SRCAP,ARFIP1,GGTA1P,GLYR1,RAB30,TNRC6A,PCSK1N,GNAS,GOLGB1,FUT10,B4GALNT4,GPER1,PCLO,STMN2,GRIA1,RFFL,GRM7,CIT,AP4S1,PACSIN2,MAN1B1,SCRG1,GABARAPL2,ZDHHC15,HP,OPALIN,HTR5A,ICA1,RAB41,TJAP1,INPP5B,OLFM3,CLVS2,CREG2,KIFC3,IPO5,CLEC18A,MAN2A2,MAP6,CHST6,MGAT3,SCAMP5,MMP16,DBNL,JAKMIP3,MTTP,MDGA1,MYO5A,MYO6,NCAM1,NPY,SLC11A2,NRGN,NUCB1,NUCB2,NUMA1,OCRL,ZDHHC22,PCSK5,PDE2A,PDE3B,ENPP2,ZDHHC8,DUSP26,PIK3C2A,PKD1,RETREG1,XRN1,PLCB2,ST8SIA5,MAPKAP1,STRN3,PACSIN1,DRAM2,RAB39A,MAPK3,SLC26A11,PTCH1,PTHLH,PTPRN,MARCH1,RAP1GAP,BEND5,GAL3ST4,TRIM68,ZDHHC4,FBXW7,ATP8B4,SGSM1,ACER3,MAP6D1,EMID1,LRRK2,SYNDIG1,ST6GALNAC6,ATAT1,KCNIP3,WLS,AP1AR,ATXN2,SMPD3,SEC14L1,GALNT10,COPZ1,SH3GL2,MYO18A,FNDC3A,ST6GAL1,CNKSR2,BCAN,SYBU,NLGN1,ST3GAL3,SEC31A,ST8SIA1,CLSTN1,SLC1A6,RPH3A,EPN2,RAB3GAP1,CCDC88A,ARFGAP1,GKAP1,CDK5RAP2,SNAP25,SNCB,SNCA,KIF13A,USP33,FNBP1,NMNAT2,GLT8D1,ERC1,CLASP2,CLSTN2,MAPK8IP3,SULF2,GANAB,NSFL1C,ACSBG1,FGD4,SYN1,SYT1,ANKRD28,DDHD2,DNMBP,CLASP1,AZIN2,SYNE1,OBSL1,SLC35G2,RNF175,CHST8,AP4E1,AKTIP,GALNT17,GZF1,CHST5,NTSR2,RUSC1,TSC2,SLC35A4,GORASP1,PITPNB,MGAT5B,LMF1,WNT7A,SPIRE1,PMEPA1,CSDE1,EVI5,STMN4,LMAN2L,GAL3ST3,ITM2C,MPPE1,PLD4,GOPC,KAT6A,CAMK1G,IFT88,AP3B2,ST8SIA2" GO: Cellular Component GO:0032587 ruffle membrane 3.65E-05 4.06E-02 4.18E-04 3.18E-03 31 84 "FGD2,APC,EPB41L5,SYNJ2,ARHGEF2,ARHGEF4,AIF1L,DNM2,PLEKHA1,PLEKHO1,RASGRP2,EPS8,SH3YL1,DLC1,FGR,INPP5K,PACSIN2,HSP90AA1,ITGAV,MYO6,SNTG1,PDE4A,PACSIN1,PTPRZ1,FERMT1,CLASP2,KANK1,WWC1,TIAM1,TPM1,SPATA13" GO: Cellular Component GO:0030017 sarcomere 4.12E-05 4.58E-02 4.68E-04 3.55E-03 59 198 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,MYOM1,DST,CACNA1D,CALM1,CAPN3,ARHGEF25,MYOM2,IGFN1,CFL2,NOS1AP,HDAC4,DMD,DNAJB6,ABCC9,FLNC,PDLIM5,MYOZ2,FERMT2,MYLK2,KCNN2,MYH3,MYH6,MYH7,MYL3,NOS1,PDE4B,TMOD2,PPP3CA,PPP3CB,PSMA6,PYGM,RPL15,RYR1,SCN8A,FHOD3,SLC8A1,SPHKAP,PALLD,SCN3B,SPTAN1,SYNE2,SYNE1,OBSL1,TIMP4,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,SYNPO2,TRPC1,SYNC" GO: Cellular Component GO:0042641 actomyosin 4.17E-05 4.64E-02 4.68E-04 3.56E-03 29 77 "ACTN1,CDC42BPA,LURAP1,SEPT7,CDC42BPB,HDAC4,DBN1,DLC1,SORBS1,SEPT9,FERMT2,SYNPO,MYH6,MYH7,MYO5A,PTK2,MYH14,MYO18A,ABLIM3,PALLD,MPRIP,STX1A,PDLIM2,TEK,TPM1,TPM3,TPM4,AMOT,VANGL2" GO: Cellular Component GO:0030027 lamellipodium 4.65E-05 5.17E-02 5.17E-04 3.93E-03 56 186 "PLEKHG5,FGD2,APBB1,APBB2,APC,DGKZ,ALS2,APP,SHTN1,ARHGEF7,WASF1,CDH2,ARHGEF6,CTNND1,DBN1,TIAM2,DNM2,ABI1,ABI2,MTSS1L,STX2,APC2,PTK2B,FER,EVL,NCKAP1,IQGAP2,WASF3,FERMT2,STMN2,GSN,ITGAV,KCNA2,DBNL,CTNNA3,SSH1,PKN2,GDPD2,PTK2,PTPN13,PTPRO,PTPRZ1,RDX,ITSN1,PPP1R9A,ABLIM3,CCDC88A,SNAP25,PALLD,FGD4,SYNE2,MCF2L,TSC1,AMOT,PLEKHH2,SPATA13" GO: Cellular Component GO:0097440 apical dendrite 6.24E-05 6.94E-02 6.87E-04 5.22E-03 11 18 "NEURL1,CLU,SEZ6,PTK2B,PPARGC1A,HCN1,RASGRF1,RGS12,CPEB3,OSBP2,SLC4A10" GO: Cellular Component GO:0097449 astrocyte projection 7.44E-05 8.29E-02 8.12E-04 6.17E-03 9 13 "APP,ADGRG1,GFAP,GLUL,GRM3,GRM5,KCNJ10,KCNK2,MT3" GO: Cellular Component GO:0044449 contractile fiber part 7.75E-05 8.63E-02 8.37E-04 6.36E-03 62 215 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,MYOM1,DST,CACNA1D,CALM1,CAPN3,ARHGEF25,MYOM2,IGFN1,CFL2,MYL6B,NOS1AP,HDAC4,DMD,DNAJB6,ABCC9,FLNC,PDLIM5,MYOZ2,FERMT2,MYLK2,KCNN2,MYH3,MYH6,MYH7,MYL3,NOS1,PDE4B,TMOD2,PLEC,PPP3CA,PPP3CB,PSMA6,PYGM,RPL15,RYR1,SCN8A,FHOD3,SLC8A1,SPHKAP,PALLD,SCN3B,SPTAN1,SYNE2,SYNE1,OBSL1,TIMP4,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,SYNPO2,TRPC1,SYNC,FXR1" GO: Cellular Component GO:0016323 basolateral plasma membrane 1.14E-04 1.26E-01 1.22E-03 9.22E-03 68 244 "ADORA1,AP2A1,ANK1,ANK2,ANK3,AQP4,CASK,ARRB1,ARRB2,NUMB,ATP1A1,SLC4A4,ATP2B1,DST,CA4,DDR1,MAP7,CDH2,SLC22A6,AKAP5,SLC4A7,HEPH,DLG2,DLG3,DLG4,SLC12A6,EGFR,STX2,ERBB2,ERBB4,MEGF11,MEGF10,RAPGEF4,HSP90AA1,IL6R,KCNC2,KCNJ4,KCNJ10,KCNJ16,MTTP,HCN1,P2RY1,PALM,PKD1,PLEC,CNNM2,PTH1R,PTK2,RASGRF1,SLC1A3,SLC8A2,SLC8A1,SLC12A2,SLC14A1,ERBIN,AJAP1,MLC1,TEK,TF,TJP1,TRPC1,CADM1,BEST1,P2RY12,NDRG4,VANGL2,PIANP,SLC4A10" GO: Cellular Component GO:0005891 voltage-gated calcium channel complex 1.22E-04 1.36E-01 1.29E-03 9.78E-03 18 41 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,NOS1AP,CACNG7,CACNG3,CACNG2,NOS1,PDE4B,PDE4D" GO: Cellular Component GO:0030132 clathrin coat of coated pit 1.24E-04 1.38E-01 1.29E-03 9.78E-03 11 19 "AP2A1,AP2A2,SYNJ1,EPS15L1,CLTA,CLTB,CLTC,TBC1D5,SNAP91,EGFR,SGIP1" GO: Cellular Component GO:0016529 sarcoplasmic reticulum 1.24E-04 1.38E-01 1.29E-03 9.78E-03 25 66 "ANK1,ANK3,ASPH,ATP2A2,CA4,CACNA2D1,CAMK2B,CAMK2D,CAMK2G,AKAP7,AKAP6,NOS1AP,DMPK,MRVI1,POMT1,JPH4,NOS1,TMEM38A,PYGM,RYR1,RYR3,SLN,SYNE2,THBS4,JPH3" GO: Cellular Component GO:0005884 actin filament 1.65E-04 1.83E-01 1.70E-03 1.29E-02 32 94 "ACTN1,ACTN2,GAS7,SHROOM2,WHRN,DAPK3,AIF1L,DBN1,DMTN,APC2,RCSD1,DLC1,FYN,IQGAP2,GCK,FERMT2,MYO5A,MYO6,PRKCZ,GDPD2,FERMT1,PALLD,COBL,TEK,TPM1,TPM3,TPM4,TSC1,AMOT,WIPF1,FMN2,WIPF2" GO: Cellular Component GO:0030665 clathrin-coated vesicle membrane 1.97E-04 2.19E-01 2.01E-03 1.52E-02 29 83 "AP2A1,AP2A2,AP1B1,AP1M1,HIP1R,CLTA,CLTB,CLTC,SLC32A1,TBC1D5,SNAP91,EGFR,NCALD,CLVS1,FCGR1A,FCGR1B,SGIP1,GAD1,GAD2,CLVS2,DBNL,MYO6,NRGN,RAB3A,SH3GL2,EPN2,SYT1,SLC17A7,AP3B2" GO: Cellular Component GO:0030285 integral component of synaptic vesicle membrane 2.12E-04 2.36E-01 2.15E-03 1.63E-02 6 7 "ATP6V1G2,SYNPR,GABRA2,SYP,SYPL1,TMEM163" GO: Cellular Component GO:0032983 kainate selective glutamate receptor complex 2.52E-04 2.81E-01 2.53E-03 1.92E-02 5 5 "GRIA4,GRIK1,GRIK2,GRIK4,GRIK5" GO: Cellular Component GO:0098802 plasma membrane receptor complex 2.67E-04 2.98E-01 2.66E-03 2.02E-02 52 180 "ABHD6,ALCAM,CNIH2,BMPR1B,SHISA7,CHRNA4,CHRNB2,DLGAP3,CNTFR,NOS1AP,CNIH3,DLG2,DLG3,DLG4,GRIN3A,SHANK1,CACNG7,EPS8,NRN1,CACNG3,CACNG2,PTK2B,OLFM1,SORBS1,GABBR1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,CPT1C,SHISA6,IL6R,IL6ST,ITGA7,ITGAM,ITGAV,OLFM3,KCNK1,STXBP5,LRRTM4,NLGN1,SHANK2,VWC2,TF,PORCN" GO: Cellular Component GO:0005768 endosome 3.59E-04 3.99E-01 3.53E-03 2.68E-02 188 826 "ADCY5,ADCY6,ADCYAP1R1,SNX30,ADRB2,KIDINS220,AP2A1,AP2A2,SNX32,OSBPL1A,TBC1D14,KIAA1324,FGD2,ALS2,APOC2,APP,ZFYVE28,MARCH3,NUMB,ASTN1,CHID1,ATP1A1,ATP1A2,ATP6V0A1,MTMR2,NIPA1,LDLRAD4,USP6,AP4M1,CPNE6,ZFYVE9,CLCN3,CLCN4,CLTA,CLTC,CRHBP,CLIP3,ABCG1,AATK,CNTNAP2,CST3,APPL1,RUBCN,ARHGAP32,GAPVD1,ZFYVE16,TBC1D5,PLEKHM1,KIAA0319,MAGI2,BLOC1S6,RABGAP1L,TRAPPC9,DYNC1I1,DNM2,ARRDC4,TOM1,OPTN,EGFR,IRAK4,TNK2,STARD3NL,CALCRL,EPHB1,ANKRD13B,RABEPK,ERBB2,VPS26C,TLR7,RRAGB,CD320,CLVS1,RPS6KC1,TBC1D16,FCGR1A,FCGR1B,AMOTL2,VTI1B,AGAP2,FLT1,ANKFY1,SYT3,TMEM175,WDR83,STAMBP,NSG2,NSG1,AP4B1,FYN,ATP8A2,DNER,TUBGCP4,WASHC2A,STARD3,GNAS,GPER1,STMN2,RAPGEF1,GRIA1,RFFL,AP4S1,PACSIN2,HMGB1,TJAP1,INPP5B,JAK2,KCNH1,CLVS2,KCNJ11,KCNK1,L1CAM,LAMP2,SYTL4,CLEC18A,ZFYVE27,SCAMP5,DBNL,BLOC1S2,MYO5A,SLC11A2,NTRK2,NUCB1,OCRL,PAK3,SNX10,ZFYVE21,MAGEL2,PACSIN1,RASGEF1B,PRKCZ,MAPK3,OCIAD1,PTPRN,MARCH1,RAB3A,RAB5B,PLEKHB2,SH3TC2,RAP1GAP,RET,LRRK2,SYNDIG1,WLS,CLIP1,AP1AR,SH3GL3,KIF16B,SEC31A,SLA,SLC11A1,SNAP25,KIF13A,TNIK,NMNAT2,TAB2,MLC1,ARC,ASTN2,SYT5,ATP11A,MGRN1,TPCN2,WASHC4,CYB561A3,ATP13A2,TF,AP4E1,GPR161,TMEM9,TLR4,RUSC1,TTPA,SGK3,UBC,ATP6V0E2,LAMP5,SLC30A3,SLC30A4,PMEPA1,TUBA1A,VPS35L,SNX27,TMEM163,SLC17A6,MVB12B,MARCH8,SNX14,ST8SIA2" GO: Cellular Component GO:0032839 dendrite cytoplasm 4.04E-04 4.50E-01 3.94E-03 2.99E-02 11 21 "CAMK2A,CANX,DLG4,GRIA2,GRIK2,GRIK3,HPCA,MAPK8,LRRK2,WLS,KCNAB1" GO: Cellular Component GO:0030120 vesicle coat 4.09E-04 4.55E-01 3.96E-03 3.00E-02 19 48 "AP2A1,AP2A2,COPB2,CLTA,CLTB,CLTC,SEC31B,SEC24C,TBC1D5,SNAP91,EGFR,NCALD,SEC24B,SEC23B,SGIP1,COPZ1,SEC31A,EPN2,TF" GO: Cellular Component GO:0034704 calcium channel complex 4.26E-04 4.74E-01 4.08E-03 3.10E-02 23 63 "ASPH,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2D,CACNA2D2,AKAP6,NOS1AP,CACNG7,CACNG3,CACNG2,NOS1,PDE4B,PDE4D,PTPA" GO: Cellular Component GO:0000139 Golgi membrane 4.42E-04 4.92E-01 4.21E-03 3.20E-02 165 716 "SYS1,GALNT16,GALNT13,AP2A1,AP1B1,HACE1,MARCH4,GOLGA7B,C6orf89,CNIH2,APP,LGR5,ARRB1,STX16,B3GALT2,ST3GAL5,AP1M1,MMD2,CABP7,ENTPD6,AP4M1,CDC42,LARGE1,COPB2,PLEKHB1,B4GALT6,NDST3,CLCN3,COG1,CLTA,CLTB,CLTC,TMEM59L,RAB26,CABP1,GAL3ST1,HS3ST5,ENTPD4,CLIP3,ABCG1,SEC24C,GALNT9,PNPLA8,GPSM1,USP6NL,ECE2,ARHGAP32,B3GAT3,CNIH3,TMEM130,SEC16A,HS3ST4,HS3ST2,TRAPPC9,CALN1,DNM2,FAM57B,GOLT1B,ST8SIA3,ATL1,RASGRP1,OPTN,SH3GLB1,APH1A,EGFR,GOLGA7,RABEPK,NCALD,RTN3,TLR7,F5,F8,CLVS1,FAM198B,ATP8A1,ST3GAL6,CHST15,FKTN,SEC24B,SCARA3,SEC23B,ARFGAP2,ATP2C1,NSG2,ST6GALNAC3,CSPG5,NSG1,FUT9,B3GAT1,AP4B1,TVP23A,GALNT15,GAD2,B4GALNT1,ATP8A2,GCNT2,ARFIP1,GGTA1P,RAB30,GNAS,GOLGB1,FUT10,B4GALNT4,GPER1,GRIA1,RFFL,AP4S1,GABARAPL2,ICA1,RAB41,CLVS2,MAN2A2,CHST6,MGAT3,SCAMP5,DBNL,NCAM1,NRGN,NUCB1,NUMA1,PKD1,ST8SIA5,RAB39A,MARCH1,RAP1GAP,GAL3ST4,ACER3,SYNDIG1,ST6GALNAC6,WLS,SMPD3,GALNT10,COPZ1,SH3GL2,MYO18A,FNDC3A,ST6GAL1,SYBU,ST3GAL3,SEC31A,ST8SIA1,CLSTN1,ARFGAP1,KIF13A,NMNAT2,ERC1,CLSTN2,MAPK8IP3,ANKRD28,RNF175,CHST8,AP4E1,GALNT17,CHST5,SLC35A4,GORASP1,PITPNB,MGAT5B,PMEPA1,LMAN2L,GAL3ST3,PLD4,GOPC,CAMK1G,ST8SIA2" GO: Cellular Component GO:0031594 neuromuscular junction 5.25E-04 5.85E-01 4.96E-03 3.76E-02 22 60 "ACHE,ANK3,APP,CDK5R1,CAMK2D,SYNGR3,COL4A5,HDAC4,SV2A,EFNA2,PCLO,GRIA1,ITGA7,KCNN3,P2RX7,SERPINE2,PTN,PPP1R9A,SLC8A3,PDZRN3,THBS4,SYNC" GO: Cellular Component GO:0044431 Golgi apparatus part 5.75E-04 6.40E-01 5.38E-03 4.09E-02 207 928 "SYS1,GALNT16,GALNT13,AP2A1,AP1B1,HACE1,KIAA1324,MARCH4,GOLGA7B,AMPH,C6orf89,CNIH2,APP,LGR5,ARRB1,RGS20,ARSE,CHID1,STX16,B3GALT2,ST3GAL5,AP1M1,GPC2,BSN,RAB29,MMD2,CA4,CABP7,ENTPD6,AP4M1,LRBA,CDC42,LARGE1,COPB2,PLEKHB1,B4GALT6,NDST3,CLCN3,COG1,CLTA,CLTB,CLTC,TMEM59L,RAB26,CABP1,GAL3ST1,HS3ST5,ENTPD4,CLIP3,ABCG1,SEC24C,GALNT9,VCAN,NCAN,SDC3,PNPLA8,GPSM1,USP6NL,ECE2,ARHGAP32,B3GAT3,CNIH3,TMEM130,SEC16A,HS3ST4,HS3ST2,TRAPPC9,CALN1,DNM2,FAM57B,GOLT1B,ST8SIA3,ATL1,RASGRP1,OPTN,SH3GLB1,APH1A,EGFR,GOLGA7,RABEPK,NCALD,RTN3,TLR7,F5,F8,CLVS1,FAM198B,ATP8A1,ST3GAL6,CHST15,FKTN,SEC24B,SCARA3,SEC23B,NBEA,ARFGAP2,ATP2C1,NSG2,ST6GALNAC3,CSPG5,NSG1,FUT9,B3GAT1,AP4B1,TVP23A,GALNT15,GAD2,B4GALNT1,SYT17,ATP8A2,INPP5K,GCNT2,ARFIP1,GGTA1P,RAB30,PCSK1N,GNAS,GOLGB1,FUT10,B4GALNT4,GPER1,PCLO,GRIA1,RFFL,CIT,AP4S1,PACSIN2,GABARAPL2,ICA1,RAB41,TJAP1,CLVS2,MAN2A2,CHST6,MGAT3,SCAMP5,MMP16,DBNL,NCAM1,SLC11A2,NRGN,NUCB1,NUCB2,NUMA1,OCRL,PCSK5,PKD1,ST8SIA5,PACSIN1,RAB39A,MARCH1,RAP1GAP,GAL3ST4,ACER3,MAP6D1,LRRK2,SYNDIG1,ST6GALNAC6,WLS,ATXN2,SMPD3,GALNT10,COPZ1,SH3GL2,MYO18A,FNDC3A,ST6GAL1,BCAN,SYBU,ST3GAL3,SEC31A,ST8SIA1,CLSTN1,ARFGAP1,SNAP25,KIF13A,FNBP1,NMNAT2,ERC1,CLASP2,CLSTN2,MAPK8IP3,SULF2,NSFL1C,ANKRD28,DNMBP,AZIN2,RNF175,CHST8,AP4E1,GALNT17,CHST5,NTSR2,SLC35A4,GORASP1,PITPNB,MGAT5B,WNT7A,PMEPA1,LMAN2L,GAL3ST3,PLD4,GOPC,CAMK1G,IFT88,AP3B2,ST8SIA2" GO: Cellular Component GO:0032279 asymmetric synapse 7.03E-04 7.82E-01 6.41E-03 4.87E-02 9 16 "ADORA1,ADORA2A,CHRM1,CHRM4,AKAP5,DBN1,GRIA1,GRIA2,GRM7" GO: Cellular Component GO:0031045 dense core granule 7.03E-04 7.82E-01 6.41E-03 4.87E-02 9 16 "ACTN1,MYRIP,CRHBP,SYT9,VPS13A,SYT1,SYT4,SYT5,SCG2" GO: Cellular Component GO:0033268 node of Ranvier 7.03E-04 7.82E-01 6.41E-03 4.87E-02 9 16 "BIN1,ANK3,SPTBN4,KCNQ2,KCNQ3,SCN2A,SCN8A,NFASC,CNTN2" GO: Cellular Component GO:0030863 cortical cytoskeleton 7.17E-04 7.98E-01 6.49E-03 4.93E-02 31 97 "ACTN1,ACTN2,ANK1,SHROOM2,SPTBN4,BSN,CDH2,MYADM,DLG4,EPB41,EPB41L2,DMTN,MTSS1L,DLC1,PCLO,GSN,ANLN,RDX,PPP1R9A,SPTAN1,SPTB,CLASP2,COBL,PDLIM2,CLASP1,TMOD1,TPM3,TPM4,PLEKHH2,WIPF1,WIPF2" GO: Cellular Component GO:0033017 sarcoplasmic reticulum membrane 7.24E-04 8.05E-01 6.50E-03 4.93E-02 16 39 "ASPH,ATP2A2,CAMK2B,CAMK2D,CAMK2G,AKAP6,NOS1AP,DMPK,JPH4,NOS1,TMEM38A,RYR1,RYR3,SLN,SYNE2,JPH3" GO: Cellular Component GO:0031674 I band 7.50E-04 8.35E-01 6.68E-03 5.07E-02 40 135 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,DST,CACNA1D,CAPN3,IGFN1,CFL2,NOS1AP,HDAC4,DMD,DNAJB6,FLNC,PDLIM5,MYOZ2,FERMT2,KCNN2,MYH6,MYH7,MYL3,NOS1,PDE4B,PPP3CA,PPP3CB,PYGM,RYR1,SCN8A,FHOD3,SLC8A1,SPHKAP,PALLD,SCN3B,SPTAN1,SYNE2,OBSL1,SYNPO2,SYNC" GO: Cellular Component GO:0045121 membrane raft 7.69E-04 8.56E-01 6.74E-03 5.12E-02 86 343 "ADCY2,ADCY5,ADCY6,ADCYAP1R1,UNC5A,ADRB2,ANK2,APP,ATP1A1,ATP1A2,ATP1B3,ATP2B1,ATP2B2,ATP2B3,RIPK1,CFLAR,SYNJ2,BTK,SCARB1,CDH2,SLC22A6,CNR1,CNTN1,AKAP6,CLIP3,CTNND1,NOS1AP,MYADM,DAPK3,DCC,DMD,DRD1,EDNRA,EDNRB,EGFR,EPHB1,STX2,ERBB2,ERBB4,PTK2B,DLC1,FCGR1A,SORBS1,FYN,GABBR1,GNAS,GPM6B,BVES,PACSIN2,HTR2A,JAK2,KCND2,KCND3,KCNMA1,KCNQ3,L1CAM,LAMP2,MOG,MDGA1,NOS1,OLR1,PDE2A,PLCD1,FXYD1,PRKCZ,MAPK3,PTCH1,RET,KIRREL1,LRRK2,SNAP25,FAIM2,UNC5B,MLC1,TEK,TLR4,TNFRSF1B,TNR,RGMB,TRPC1,TSC2,RFTN2,P2RY12,LAT2,CRB2,LRP8" GO: Cellular Component GO:0098857 membrane microdomain 7.69E-04 8.56E-01 6.74E-03 5.12E-02 86 343 "ADCY2,ADCY5,ADCY6,ADCYAP1R1,UNC5A,ADRB2,ANK2,APP,ATP1A1,ATP1A2,ATP1B3,ATP2B1,ATP2B2,ATP2B3,RIPK1,CFLAR,SYNJ2,BTK,SCARB1,CDH2,SLC22A6,CNR1,CNTN1,AKAP6,CLIP3,CTNND1,NOS1AP,MYADM,DAPK3,DCC,DMD,DRD1,EDNRA,EDNRB,EGFR,EPHB1,STX2,ERBB2,ERBB4,PTK2B,DLC1,FCGR1A,SORBS1,FYN,GABBR1,GNAS,GPM6B,BVES,PACSIN2,HTR2A,JAK2,KCND2,KCND3,KCNMA1,KCNQ3,L1CAM,LAMP2,MOG,MDGA1,NOS1,OLR1,PDE2A,PLCD1,FXYD1,PRKCZ,MAPK3,PTCH1,RET,KIRREL1,LRRK2,SNAP25,FAIM2,UNC5B,MLC1,TEK,TLR4,TNFRSF1B,TNR,RGMB,TRPC1,TSC2,RFTN2,P2RY12,LAT2,CRB2,LRP8" GO: Cellular Component GO:0030018 Z disc 8.86E-04 9.86E-01 7.71E-03 5.85E-02 36 119 "ACTN1,ACTN2,BIN1,ANK1,ANK2,ANK3,DST,CACNA1D,CAPN3,IGFN1,NOS1AP,HDAC4,DMD,DNAJB6,FLNC,PDLIM5,MYOZ2,KCNN2,MYH6,MYH7,NOS1,PDE4B,PPP3CA,PPP3CB,PYGM,SCN8A,FHOD3,SLC8A1,SPHKAP,PALLD,SCN3B,SPTAN1,SYNE2,OBSL1,SYNPO2,SYNC" GO: Cellular Component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane 9.87E-04 1.00E+00 8.52E-03 6.47E-02 33 107 "ESYT2,KCNAB2,ARRB1,ATP2A2,RGS11,RGS9,BTK,RGS6,DLG4,DTNA,TNK2,GPHN,PTK2B,FER,FGR,FYN,GNAL,GNAO1,GNAS,GNG3,GNG4,FERMT2,JAK1,JAK2,MATK,GNG2,PTK2,RGS7,KCNIP1,RYR1,MCF2L,TIAM1,KCNAB1" GO: Cellular Component GO:0005773 vacuole 1.13E-03 1.00E+00 9.65E-03 7.33E-02 263 1223 "ADCY5,ADCY6,ADCYAP1R1,SNX30,ADRB2,KIDINS220,AP2A1,AP2A2,AP1B1,SNX32,OSBPL1A,TBC1D14,KIAA1324,SRPX,DOC2A,ANK3,FGD2,ALS2,APOC2,APP,SLC7A14,ZFYVE28,ARRB1,MARCH3,NUMB,ASTN1,CHID1,ATP1A1,ATP1A2,ATP6V1G2,ATP6V0A1,ARHGEF7,BTK,MTMR2,AP1M1,GYG2,NIPA1,GPC2,RAB29,LDLRAD4,HAP1,USP6,SCARB1,AP4M1,LRBA,CDC42,CHGA,CPNE6,ZFYVE9,PPT2,CLCN3,CLCN4,TPP1,CLTA,CLTC,CP,ENTPD4,CRHBP,CLIP3,ABCG1,AATK,VCAN,NCAN,CNTNAP2,CST3,SDC3,APPL1,RUBCN,ARHGAP32,GAPVD1,ZFYVE16,TBC1D5,PLEKHM1,KIAA0319,MAGI2,BLOC1S6,RABGAP1L,TRAPPC9,DYNC1I1,DNM2,ARRDC4,TOM1,EEF1A2,RASGRP1,SIDT2,OPTN,SH3GLB1,EGFR,IRAK4,TNK2,STARD3NL,CALCRL,EPHB1,ANKRD13B,RABEPK,ERBB2,TMEM74,VPS26C,TLR7,RRAGB,CD320,CLVS1,RPS6KC1,TBC1D16,FCGR1A,FCGR1B,FGFR3,AMOTL2,PCYOX1,VTI1B,AGAP2,FLT1,ANKFY1,SYT3,TMEM175,WDR83,STAMBP,ATP6V1H,NSG2,CSPG5,NSG1,AP4B1,FYN,GAA,GALC,ATP8A2,CPLX2,DNER,TUBGCP4,WASHC2A,GFAP,STARD3,GNAS,GPER1,STMN2,RAPGEF1,GRIA1,RFFL,CIT,AP4S1,GYG1,PACSIN2,HMGB1,GABARAPL2,HSP90AA1,TJAP1,INPP5B,JAK2,KCNH1,CLVS2,KCNJ11,KCNK1,KIF2A,KIT,L1CAM,LAMP2,SYTL4,CLEC18A,ZFYVE27,TM6SF1,SCAMP5,DBNL,BLOC1S2,MYO5A,MYO6,MYO7A,NCF2,NOS1,NPPA,SLC11A2,NTRK2,NUCB1,TBC1D25,OCRL,PAK3,PIK3CD,SNX10,ZFYVE21,MAGEL2,PACSIN1,DRAM2,RASGEF1B,RAB39A,PRKCZ,MAPK3,EPDR1,SLC26A11,OCIAD1,PTPRN,MARCH1,RAB3A,RAB5B,PLEKHB2,SH3TC2,ATG16L1,RAP1GAP,RET,LRRK2,SYNDIG1,WLS,CLIP1,AP1AR,SH3GL3,KIF16B,AMBRA1,BCAN,SEC31A,SLA,SLC11A1,SLC12A4,NAPB,SNAP25,SNCA,KIF13A,LMBRD1,USP33,TNIK,FNBP1,NMNAT2,TAB2,MLC1,VAMP1,TMEM150C,ARC,ASTN2,SYT5,ATP11A,MGRN1,NEU4,TPCN2,WASHC4,CYB561A3,ATP13A2,TF,AP4E1,GPR161,TMEM9,TLR4,RUSC1,TSC2,TTC3,TTPA,SGK3,UBC,LAT2,ATP6V0E2,SPHK2,LAMP5,SLC30A3,SLC30A4,PMEPA1,TUBA1A,HPS4,VPS35L,SNX27,TMEM163,ITM2C,SLC17A6,MVB12B,GOPC,MARCH8,SNX14,ST8SIA2" GO: Cellular Component GO:0030662 coated vesicle membrane 1.14E-03 1.00E+00 9.68E-03 7.35E-02 41 142 "AP2A1,AP2A2,AP1B1,CNIH2,AP1M1,HIP1R,COPB2,CLTA,CLTB,CLTC,SEC31B,SLC32A1,SEC24C,TBC1D5,CNIH3,SNAP91,EGFR,NCALD,CLVS1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SGIP1,GAD1,GAD2,GRIA1,CLVS2,DBNL,MYO6,NRGN,RAB3A,COPZ1,SH3GL2,SEC31A,EPN2,SYT1,TF,SLC17A7,AP3B2" GO: Cellular Component GO:0044291 cell-cell contact zone 1.15E-03 1.00E+00 9.73E-03 7.39E-02 24 71 "ACTN1,ADRA1B,ANK2,ANK3,PKP4,ATP1A1,ATP1A2,ATP2A2,CAMK2D,CDH2,AKAP6,FGF13,OPALIN,KCNJ11,CTNNA3,PCDH9,PTK2,SCN2A,SCN4B,SLC8A1,SPTAN1,OBSL1,TIAM1,TJP1" GO: Cellular Component GO:0044448 cell cortex part 1.20E-03 1.00E+00 1.00E-02 7.61E-02 40 138 "ACTN1,ACTN2,OSBPL8,ANK1,SHROOM2,SPTBN4,ASPH,BSN,SEPT7,CDH2,MYRIP,MYADM,DLG4,EPB41,EPB41L2,DMTN,MTSS1L,DLC1,SEPT9,GCK,PCLO,GSN,ANLN,PRKCZ,RDX,PPP1R9A,SPTAN1,SPTB,CLASP2,PHLDB1,COBL,EXOC7,PDLIM2,CLASP1,TMOD1,TPM3,TPM4,PLEKHH2,WIPF1,WIPF2" GO: Cellular Component GO:0071565 nBAF complex 1.23E-03 1.00E+00 1.02E-02 7.77E-02 8 14 "DPF1,ARID1A,ACTL6B,SMARCA4,SMARCC2,SMARCD3,SMARCE1,DPF3" GO: Cellular Component GO:0005901 caveola 1.30E-03 1.00E+00 1.07E-02 8.12E-02 30 96 "ADCYAP1R1,ADRB2,ATP1A1,ATP1A2,ATP1B3,SCARB1,SLC22A6,AKAP6,CTNND1,NOS1AP,DRD1,ERBB4,DLC1,SORBS1,BVES,PACSIN2,HTR2A,JAK2,KCND2,KCND3,KCNMA1,NOS1,FXYD1,MAPK3,PTCH1,LRRK2,MLC1,TSC2,P2RY12,LRP8" GO: Cellular Component GO:0005862 muscle thin filament tropomyosin 1.39E-03 1.00E+00 1.12E-02 8.52E-02 4 4 "TPM1,TPM2,TPM3,TPM4" GO: Cellular Component GO:0033269 internode region of axon 1.39E-03 1.00E+00 1.12E-02 8.52E-02 4 4 "ERMN,TUBB4A,MBP,PARD3" GO: Cellular Component GO:1990635 proximal dendrite 1.39E-03 1.00E+00 1.12E-02 8.52E-02 4 4 "SYNCRIP,PTPN5,PPP5C,KCNAB1" GO: Cellular Component GO:0099513 polymeric cytoskeletal fiber 1.68E-03 1.00E+00 1.35E-02 1.02E-01 160 712 "ACTN1,ACTN2,AXIN2,ADORA2A,MTUS1,KIF6,KCNAB2,APC,GAS7,SHTN1,SHROOM2,RGS20,DNAH17,DYNLL1,KIF1A,TTLL9,DST,SYNJ1,SYNJ2,CALM1,MAP7,PRC1,KRIT1,INA,ARHGEF2,CDC27,DLGAP2,WHRN,IFFO1,CRHBP,NCOR1,FEZ1,KATNAL2,SNPH,KIF26A,DAPK3,AIF1L,DBN1,DCTN1,CEP170,KIF19,DNM1,DNAH9,DYNC1I1,DNM2,DPYSL2,DNM1L,EML1,TUBD1,DMTN,APC2,RCSD1,KATNAL1,REEP2,TUBA1B,TUBB3,TUBB4A,DLC1,FGF13,CAMSAP1,DCTN2,STAU2,TPPP3,FYN,NEK6,IQGAP2,DISC1,SEPT9,GCK,TUBGCP4,TUBA8,GFAP,DCLK2,FERMT2,PSRC1,GPER1,EML4,TUBA1C,TPPP,SPACA9,KIF3A,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,STMN1,MAP2,MAP4,MAP6,MAPT,MID1,MT3,MYO5A,MYO6,NEFM,NEFH,NUMA1,ODF2,JAKMIP1,FSD1,PRKCZ,PRPH,BCAS3,LRRC49,GDPD2,EML5,FIGN,TTLL7,TCP11L1,MAP6D1,ATAT1,CLIP1,KIF27,KIF21A,FERMT1,KIF16B,SYBU,WDR47,SLC8A2,SLC8A1,RADIL,SLC8A3,SIRT2,CDK5RAP3,SHANK2,CDK5RAP2,KIF13A,PALLD,KIF21B,KIF1B,CLASP2,SS18,COBL,CAMSAP2,TBL1X,CLASP1,TEK,DNAH7,TIAM1,TPM1,TPM3,TPM4,NEIL2,RUSC1,TSC1,TUBB2A,TUBB1,AMOT,MICAL1,WIPF1,CLIP2,KLC2,FMN2,EML6,SYNC,TUBA1A,WIPF2,DNAH10" GO: Cellular Component GO:0032588 trans-Golgi network membrane 2.10E-03 1.00E+00 1.65E-02 1.25E-01 26 82 "SYS1,AP1B1,APP,LGR5,STX16,AP1M1,CABP7,AP4M1,COG1,CLTA,CLTC,CLIP3,USP6NL,CALN1,RABEPK,CLVS1,AP4B1,ARFIP1,GNAS,AP4S1,CLVS2,SCAMP5,MARCH1,KIF13A,AP4E1,PLD4" GO: Cellular Component GO:1902710 GABA receptor complex 2.11E-03 1.00E+00 1.65E-02 1.25E-01 9 18 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2" GO: Cellular Component GO:1902711 GABA-A receptor complex 2.11E-03 1.00E+00 1.65E-02 1.25E-01 9 18 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2" GO: Cellular Component GO:0070852 cell body fiber 2.17E-03 1.00E+00 1.69E-02 1.28E-01 7 12 "APC,SPTBN4,SACS,HTR2A,KCNJ11,PENK,CADM1" GO: Cellular Component GO:0014704 intercalated disc 2.20E-03 1.00E+00 1.70E-02 1.29E-01 20 58 "ACTN1,ADRA1B,ANK2,ANK3,ATP1A1,ATP1A2,ATP2A2,CAMK2D,CDH2,AKAP6,FGF13,KCNJ11,CTNNA3,PTK2,SCN2A,SCN4B,SLC8A1,SPTAN1,OBSL1,TJP1" GO: Cellular Component GO:0097038 perinuclear endoplasmic reticulum 2.22E-03 1.00E+00 1.71E-02 1.30E-01 8 15 "OSBPL6,SYT6,OSBPL3,DBI,KCND2,KCND3,PIK3R1,GDPD5" GO: Cellular Component GO:0030117 membrane coat 2.30E-03 1.00E+00 1.74E-02 1.32E-01 29 95 "AP2A1,AP2A2,AP1B1,SYNJ1,AP1M1,AP4M1,COPB2,EPS15L1,CLTA,CLTB,CLTC,SEC31B,SEC24C,TBC1D5,SNAP91,DNM1,EGFR,NCALD,SEC24B,SEC23B,SGIP1,AP4B1,LRRN3,COPZ1,SEC31A,EPN2,TF,AP4E1,AP3B2" GO: Cellular Component GO:0048475 coated membrane 2.30E-03 1.00E+00 1.74E-02 1.32E-01 29 95 "AP2A1,AP2A2,AP1B1,SYNJ1,AP1M1,AP4M1,COPB2,EPS15L1,CLTA,CLTB,CLTC,SEC31B,SEC24C,TBC1D5,SNAP91,DNM1,EGFR,NCALD,SEC24B,SEC23B,SGIP1,AP4B1,LRRN3,COPZ1,SEC31A,EPN2,TF,AP4E1,AP3B2" GO: Cellular Component GO:0030666 endocytic vesicle membrane 2.37E-03 1.00E+00 1.78E-02 1.35E-01 43 156 "AP2A1,AP2A2,AP1B1,ATP6V0A1,AP1M1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SCARB1,CLTC,PICK1,CYBB,TBC1D5,SNAP91,DLG4,DNM2,EGFR,RAB9B,CLVS1,CACNG3,CACNG2,FCGR1A,FCGR1B,SGIP1,GRIA1,GRIA2,GRIA4,INPP5B,CLVS2,LAMP2,MSR1,OCRL,RAB39A,PTCH1,WLS,SH3GL2,EPN2,SLC11A1,GPR161,UBC,WNT7A,ATP6V0E2" GO: Cellular Component GO:0030125 clathrin vesicle coat 2.51E-03 1.00E+00 1.87E-02 1.42E-01 11 25 "AP2A1,AP2A2,CLTA,CLTB,CLTC,TBC1D5,SNAP91,EGFR,NCALD,SGIP1,EPN2" GO: Cellular Component GO:0017053 transcriptional repressor complex 2.61E-03 1.00E+00 1.94E-02 1.47E-01 25 79 "MTA3,PHF12,MIER1,JAZF1,NCOR1,NCOR2,CHD5,APPL1,HDAC4,HMGB1,INSM1,RCOR2,ARID4A,RBBP8,ELP2,SALL1,SMARCC2,SMARCE1,RCOR3,TBL1X,TBX15,NACC2,CBX5,HEY2,ZBTB16" GO: Cellular Component GO:0030118 clathrin coat 2.68E-03 1.00E+00 1.98E-02 1.50E-01 18 51 "AP2A1,AP2A2,AP1B1,SYNJ1,AP1M1,AP4M1,EPS15L1,CLTA,CLTB,CLTC,TBC1D5,SNAP91,EGFR,NCALD,SGIP1,AP4B1,LRRN3,EPN2" GO: Cellular Component GO:0005871 kinesin complex 2.74E-03 1.00E+00 2.01E-02 1.52E-01 19 55 "KIF6,KIF1A,KIF26A,KIF19,DISC1,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,KIF7,KIF27,KIF21A,KIF16B,KIF13A,KIF21B,KIF1B,KLC2" GO: Cellular Component GO:0034399 nuclear periphery 2.77E-03 1.00E+00 2.02E-02 1.53E-01 38 135 "CASK,SPTBN4,BLM,RUNX1T1,CFL2,AHCTF1,NCOR2,PHACTR3,MATR3,ATN1,TENM1,SRRM1,SORBS1,TCERG1,ATF7,PSIP1,IFI16,JAK2,IPO5,MAP2,MAPT,MBD1,HNRNPM,NUMA1,OGG1,TNPO2,PRKCZ,PSMA6,FIGN,RGS12,RNASEL,SATB1,ATXN1,ATXN7,SFPQ,SCAF8,SATB2,SMARCAD1" GO: Cellular Component GO:0099512 supramolecular fiber 2.87E-03 1.00E+00 2.07E-02 1.57E-01 160 721 "ACTN1,ACTN2,AXIN2,ADORA2A,MTUS1,KIF6,KCNAB2,APC,GAS7,SHTN1,SHROOM2,RGS20,DNAH17,DYNLL1,KIF1A,TTLL9,DST,SYNJ1,SYNJ2,CALM1,MAP7,PRC1,KRIT1,INA,ARHGEF2,CDC27,DLGAP2,WHRN,IFFO1,CRHBP,NCOR1,FEZ1,KATNAL2,SNPH,KIF26A,DAPK3,AIF1L,DBN1,DCTN1,CEP170,KIF19,DNM1,DNAH9,DYNC1I1,DNM2,DPYSL2,DNM1L,EML1,TUBD1,DMTN,APC2,RCSD1,KATNAL1,REEP2,TUBA1B,TUBB3,TUBB4A,DLC1,FGF13,CAMSAP1,DCTN2,STAU2,TPPP3,FYN,NEK6,IQGAP2,DISC1,SEPT9,GCK,TUBGCP4,TUBA8,GFAP,DCLK2,FERMT2,PSRC1,GPER1,EML4,TUBA1C,TPPP,SPACA9,KIF3A,TUBB2B,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,STMN1,MAP2,MAP4,MAP6,MAPT,MID1,MT3,MYO5A,MYO6,NEFM,NEFH,NUMA1,ODF2,JAKMIP1,FSD1,PRKCZ,PRPH,BCAS3,LRRC49,GDPD2,EML5,FIGN,TTLL7,TCP11L1,MAP6D1,ATAT1,CLIP1,KIF27,KIF21A,FERMT1,KIF16B,SYBU,WDR47,SLC8A2,SLC8A1,RADIL,SLC8A3,SIRT2,CDK5RAP3,SHANK2,CDK5RAP2,KIF13A,PALLD,KIF21B,KIF1B,CLASP2,SS18,COBL,CAMSAP2,TBL1X,CLASP1,TEK,DNAH7,TIAM1,TPM1,TPM3,TPM4,NEIL2,RUSC1,TSC1,TUBB2A,TUBB1,AMOT,MICAL1,WIPF1,CLIP2,KLC2,FMN2,EML6,SYNC,TUBA1A,WIPF2,DNAH10" GO: Cellular Component GO:0044853 plasma membrane raft 2.96E-03 1.00E+00 2.11E-02 1.60E-01 31 105 "ADCYAP1R1,ADRB2,ATP1A1,ATP1A2,ATP1B3,SCARB1,CDH2,SLC22A6,AKAP6,CTNND1,NOS1AP,DRD1,ERBB4,DLC1,SORBS1,BVES,PACSIN2,HTR2A,JAK2,KCND2,KCND3,KCNMA1,NOS1,FXYD1,MAPK3,PTCH1,LRRK2,MLC1,TSC2,P2RY12,LRP8" GO: Cellular Component GO:0016363 nuclear matrix 2.96E-03 1.00E+00 2.11E-02 1.60E-01 31 105 "CASK,SPTBN4,BLM,RUNX1T1,CFL2,AHCTF1,NCOR2,PHACTR3,MATR3,ATN1,TENM1,SRRM1,SORBS1,TCERG1,JAK2,MBD1,HNRNPM,NUMA1,OGG1,PRKCZ,PSMA6,FIGN,RGS12,RNASEL,SATB1,ATXN1,ATXN7,SFPQ,SCAF8,SATB2,SMARCAD1" GO: Cellular Component GO:0031901 early endosome membrane 3.14E-03 1.00E+00 2.22E-02 1.69E-01 33 114 "FGD2,ZFYVE28,MARCH3,MTMR2,LDLRAD4,ZFYVE9,CLCN3,CLCN4,CLIP3,APPL1,ZFYVE16,KIAA0319,EGFR,EPHB1,CLVS1,FCGR1A,FCGR1B,WASHC2A,INPP5B,KCNH1,CLVS2,OCRL,MARCH1,RAB5B,SYNDIG1,WLS,SH3GL3,KIF16B,LAMP5,PMEPA1,SNX27,TMEM163,MARCH8" GO: Cellular Component GO:0030139 endocytic vesicle 3.48E-03 1.00E+00 2.45E-02 1.86E-01 66 265 "CPNE2,PLEKHG5,AP2A1,AP2A2,AP1B1,ARRB2,ATP6V0A1,AP1M1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SCARB1,CPNE6,CLCN3,NRXN1,CLTC,PICK1,CYBB,TBC1D5,SNAP91,DLG4,DNM2,EGFR,RAB9B,TLR7,CLVS1,CACNG3,CACNG2,FCGR1A,FCGR1B,SGIP1,RAPGEF6,GRIA1,GRIA2,GRIA4,HBA1,HP,HSP90AA1,INPP5B,ITGAV,CLVS2,LAMP2,MSR1,MYO6,NCF2,OCRL,NLGN3,SH3KBP1,RAB39A,PTCH1,RAB5B,WLS,ITSN1,SH3GL2,AMBRA1,EPN2,SLC11A1,LMBRD1,TF,GPR161,UBC,AMOT,WNT7A,ATP6V0E2,PLD4" GO: Cellular Component GO:0032591 dendritic spine membrane 3.82E-03 1.00E+00 2.64E-02 2.01E-01 6 10 "ATP2B1,AKAP5,GPER1,GRIA1,PALM,DDN" GO: Cellular Component GO:0035253 ciliary rootlet 3.82E-03 1.00E+00 2.64E-02 2.01E-01 6 10 "APP,RAB28,KIF5A,KIF5C,KLC1,KLC2" GO: Cellular Component GO:0005883 neurofilament 3.82E-03 1.00E+00 2.64E-02 2.01E-01 6 10 "INA,DLGAP2,NEFM,NEFH,PRPH,SHANK2" GO: Cellular Component GO:0005769 early endosome 4.03E-03 1.00E+00 2.77E-02 2.10E-01 76 314 "ADRB2,FGD2,ALS2,APOC2,ZFYVE28,MARCH3,NUMB,MTMR2,NIPA1,LDLRAD4,ZFYVE9,CLCN3,CLCN4,CLIP3,CNTNAP2,APPL1,RUBCN,ZFYVE16,KIAA0319,RABGAP1L,TRAPPC9,ARRDC4,TOM1,EGFR,EPHB1,ANKRD13B,CLVS1,RPS6KC1,TBC1D16,FCGR1A,FCGR1B,ANKFY1,STAMBP,DNER,WASHC2A,GPER1,RAPGEF1,GRIA1,PACSIN2,HMGB1,INPP5B,KCNH1,CLVS2,DBNL,MYO5A,SLC11A2,NUCB1,OCRL,MAGEL2,RASGEF1B,MAPK3,MARCH1,RAB5B,RAP1GAP,RET,SYNDIG1,WLS,AP1AR,SH3GL3,KIF16B,MLC1,ATP11A,MGRN1,WASHC4,TF,RUSC1,SGK3,LAMP5,PMEPA1,VPS35L,SNX27,TMEM163,SLC17A6,MVB12B,MARCH8,ST8SIA2" GO: Cellular Component GO:0005875 microtubule associated complex 4.21E-03 1.00E+00 2.87E-02 2.18E-01 42 156 "KIF6,SHTN1,DNAH17,DYNLL1,KIF1A,MAP7,KIF26A,DNAL1,DCTN1,KIF19,DNAH9,DYNC1I1,EML1,DCTN4,RGPD5,DCTN2,DISC1,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KLC1,MAP2,MAP4,MAPT,MID1,DNHD1,KIF7,KIF27,KIF21A,KIF16B,KIF13A,KIF21B,KIF1B,STAU1,DNAH7,CLIP2,KLC2,DNALI1,LRP8,DNAH10" GO: Cellular Component GO:0019897 extrinsic component of plasma membrane 4.48E-03 1.00E+00 3.04E-02 2.31E-01 41 152 "ESYT2,KCNAB2,APC,ARRB1,NUMB,ATP2A2,RGS11,RGS9,BTK,CDH2,RGS6,DLG4,DTNA,TNK2,GPHN,APC2,PTK2B,FER,FGR,FYN,GNAL,GNAO1,GNAS,GNG3,GNG4,FERMT2,JAK1,JAK2,MATK,OLR1,GNG2,SERPINE2,SYTL2,PTK2,RGS7,KCNIP1,RYR1,MCF2L,TF,TIAM1,KCNAB1" GO: Cellular Component GO:0097418 neurofibrillary tangle 4.69E-03 1.00E+00 3.16E-02 2.40E-01 4 5 "CLU,MAPT,NEFM,NEFH" GO: Cellular Component GO:0097517 contractile actin filament bundle 6.24E-03 1.00E+00 4.16E-02 3.16E-01 21 67 "ACTN1,SEPT7,DLC1,SORBS1,SEPT9,FERMT2,SYNPO,MYH6,MYH7,PTK2,MYH14,ABLIM3,PALLD,MPRIP,PDLIM2,TEK,TPM1,TPM3,TPM4,AMOT,VANGL2" GO: Cellular Component GO:0001725 stress fiber 6.24E-03 1.00E+00 4.16E-02 3.16E-01 21 67 "ACTN1,SEPT7,DLC1,SORBS1,SEPT9,FERMT2,SYNPO,MYH6,MYH7,PTK2,MYH14,ABLIM3,PALLD,MPRIP,PDLIM2,TEK,TPM1,TPM3,TPM4,AMOT,VANGL2" GO: Cellular Component GO:0032838 plasma membrane bounded cell projection cytoplasm 6.42E-03 1.00E+00 4.25E-02 3.23E-01 20 63 "KIF1A,HAP1,CAMK2A,CANX,BLOC1S6,DLG4,GRIA2,GRIK2,GRIK3,KIF3A,HPCA,BLOC1S2,OPA1,MAPK8,LRRK2,WLS,KIF1B,UCHL1,KCNAB1,AP3B2" GO: Cellular Component GO:0001518 voltage-gated sodium channel complex 6.69E-03 1.00E+00 4.29E-02 3.26E-01 7 14 "SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCN3B" GO: Cellular Component GO:0030128 clathrin coat of endocytic vesicle 6.69E-03 1.00E+00 4.29E-02 3.26E-01 7 14 "AP2A1,AP2A2,TBC1D5,SNAP91,EGFR,SGIP1,EPN2" GO: Cellular Component GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane 6.75E-03 1.00E+00 4.29E-02 3.26E-01 5 8 "SLC32A1,GAD1,GAD2,RAB3A,SYT1" GO: Cellular Component GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle 6.75E-03 1.00E+00 4.29E-02 3.26E-01 5 8 "SLC32A1,GAD1,GAD2,RAB3A,SYT1" GO: Cellular Component GO:0014731 spectrin-associated cytoskeleton 6.75E-03 1.00E+00 4.29E-02 3.26E-01 5 8 "ANK1,ANK3,EPB41,DMTN,SPTB" GO: Cellular Component GO:0032584 growth cone membrane 6.75E-03 1.00E+00 4.29E-02 3.26E-01 5 8 "DCC,GAP43,ZFYVE27,EXOC7,LAMP5" GO: Cellular Component GO:0031209 SCAR complex 6.75E-03 1.00E+00 4.29E-02 3.26E-01 5 8 "WASF1,ABI1,ABI2,NCKAP1,NCKAP1L" GO: Cellular Component GO:0030864 cortical actin cytoskeleton 7.52E-03 1.00E+00 4.76E-02 3.61E-01 21 68 "ACTN1,ACTN2,SHROOM2,SPTBN4,CDH2,MYADM,EPB41,EPB41L2,MTSS1L,DLC1,GSN,ANLN,RDX,PPP1R9A,SPTAN1,SPTB,COBL,PDLIM2,PLEKHH2,WIPF1,WIPF2" GO: Cellular Component GO:1990761 growth cone lamellipodium 7.67E-03 1.00E+00 4.77E-02 3.62E-01 3 3 "APBB1,APP,PPP1R9A" GO: Cellular Component GO:0070110 ciliary neurotrophic factor receptor complex 7.67E-03 1.00E+00 4.77E-02 3.62E-01 3 3 "CNTFR,IL6R,IL6ST" GO: Cellular Component GO:0005594 collagen type IX trimer 7.67E-03 1.00E+00 4.77E-02 3.62E-01 3 3 "COL9A1,COL9A2,COL9A3" GO: Cellular Component GO:0005912 adherens junction 7.88E-03 1.00E+00 4.87E-02 3.70E-01 109 484 "ACTN1,ACTN2,ADD1,ALCAM,PPFIA1,APC,EPB41L5,SHROOM2,CASK,SPTBN4,NUMB,STX16,CADM3,ADAM15,DST,ARHGEF7,WASF1,CD81,ARHGEF2,CDC42,CDH2,MAGI1,ARHGAP22,CLTC,TJP2,CNN3,NECTIN3,AKAP12,CTNND1,CTNND2,ARHGAP24,AIF1L,GIT2,CD99L2,DNM2,PDCD6IP,EGFR,ABI2,SORBS3,TNK2,EPB41L2,EPHA5,PTK2B,DLC1,FGFR3,FHL1,EVL,FLNC,FLT1,SORBS1,NCKAP1,RND1,FERMT2,GSN,PACSIN2,HNRNPK,DOCK7,ITGA7,ITGAV,JAK1,KIFC3,L1CAM,LIG4,LIMS1,AFDN,CD200,GIT1,CTNNA3,LAYN,DDR2,OXTR,PDPK1,ZFYVE21,PLEC,SH3KBP1,MAPK3,PTK2,RDX,RPL38,ATAT1,FERMT1,ASAP3,LIMS2,PALLD,USP33,ARHGAP26,SPTAN1,NFASC,CLASP2,MPRIP,AJAP1,SYNE2,PDLIM2,CLASP1,TNS2,TEK,TJP1,PARD3,TNS1,TPM4,ZNF384,SYNPO2,CADM1,FLRT2,FLRT1,CADM2,WNK3,NUP214,PIANP" GO: Cellular Component GO:0030135 coated vesicle 8.05E-03 1.00E+00 4.95E-02 3.76E-01 59 241 "CPNE2,AP2A1,AP2A2,AP1B1,CNIH2,APP,NUMB,AP1M1,HIP1R,COPB2,CPNE6,CLTA,CLTB,CLTC,SEC31B,SLC32A1,SEC24C,TBC1D5,CNIH3,SNAP91,DNM2,EDN1,EGFR,TNK2,NCALD,F5,F8,CLVS1,FCGR1A,FCGR1B,SEC24B,SEC23B,VTI1B,SGIP1,GAD1,GAD2,GRIA1,CLVS2,DBNL,MYO6,NRGN,OCRL,PIK3C2A,PACSIN1,RAB3A,COPZ1,SH3GL2,SEC31A,EPN2,LMBRD1,FCHO1,MLC1,SYT1,TF,LMAN2L,SLC17A7,GOPC,VANGL2,AP3B2" Human Phenotype HP:0200134 Epileptic encephalopathy 4.05E-09 2.43E-05 2.43E-05 2.26E-04 35 66 "PCDH19,KCNT1,SYNJ1,CACNA1A,NRXN1,DNM1,DNM1L,EEF1A2,FGF12,GABRA1,GABRB1,GABRB3,GABRG2,GNAO1,GRIN2D,DOCK7,KCNA2,KCNB1,KCNQ2,MEF2C,HCN1,ROGDI,SCN2A,SCN8A,ARX,ST3GAL3,SLC1A2,SLC6A1,SPTAN1,STXBP1,ARHGEF9,PLCB1,SZT2,FRRS1L,AP3B2" Human Phenotype HP:0000514 Slow saccadic eye movements 5.31E-07 3.18E-03 1.34E-03 1.24E-02 20 33 "ALS2,ATP2B3,FBXO7,NOP56,GJB1,ELOVL5,TMEM240,MAPT,MOBP,PDYN,PEX2,ATXN1,ATXN2,ATXN7,SLCO1A2,SNCA,VAMP1,ATP13A2,PIK3R5,GJC2" Human Phenotype HP:0001255 Psychomotor developmental delay 6.68E-07 4.01E-03 1.34E-03 1.24E-02 427 1762 "DGCR6,ARID1A,ADAR,KLRC4,ADCY5,SLC12A5,PTCHD1,KIDINS220,NLGN4X,HECW2,PCDH19,HACE1,NR0B1,CC2D2A,PLA2G6,LTBP4,KCNT1,BIN1,AMT,CDC42BPA,ANK1,ANK3,KCNAB2,ALS2,APP,SLC7A14,PRX,CASK,ARHGDIA,CDK13,ASCL1,ASPA,PTCH2,ALDH4A1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,ATP2B3,ALDH7A1,KIF1A,BBS2,MPDZ,BCS1L,FGF17,BLM,PROM1,SYNJ1,ST3GAL5,BTK,MTMR2,CFAP410,CA4,CA8,CACNA1A,CACNA1D,ISPD,CBS,AIFM1,AP4M1,LRBA,LARGE1,CRLF1,CFL2,ADGRG1,CHM,CHN1,CHRNA4,RAB33A,CLCN4,NRXN1,NIPBL,ARHGEF6,COL11A2,SMARCAL1,RTTN,CPS1,PREPL,C2CD2,SH2B1,SEC24C,CNTNAP2,CTNND2,RUBCN,CX3CR1,CYBB,RIPOR2,FRMPD4,HDAC4,EARS2,MATR3,KIAA0586,DBT,DCC,DNAJC6,ZEB2,ZBTB24,B3GAT3,KIAA0753,SACS,ARNT2,DLG2,DLG3,RAB39B,DMD,DNM1,DMPK,MED12,TRAPPC9,CDON,DNM2,SLC12A6,DPH1,DPP6,DSCAM,GNE,DTNA,MAMLD1,DYRK1A,ABCC9,USH1C,WDPCP,EDN1,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,OPTN,EGFR,AASS,BSCL2,ELN,EML1,C8orf37,EMX2,VPS13B,EPB41L1,COQ7,ERBB4,ERCC2,CDHR1,APC2,ADGRV1,EYA1,CACNG2,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGF14,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,APOPT1,DLL3,AP4B1,MEGF10,GABRA1,GABRB3,GABRG2,GAD1,ZMYND11,B4GALNT1,ERAP1,ATP8A2,INPP5K,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,GFAP,MMADHC,GHR,PPARGC1A,KIRREL3,GJB1,GK,GLDC,GLI2,GNAO1,GNAS,GPT2,GP1BB,PARD3B,GRIK2,GRIN1,GRM1,CIT,IL1RAPL1,MFSD2A,AP4S1,HBA1,MAN1B1,AGBL5,HNMT,HNRNPK,ZDHHC15,IDH3B,IGF1,RBPJ,TMEM240,IL12A,RIPPLY2,SLC6A17,TUBB2B,ITGA7,KCNA2,KCNH1,KCNJ5,KCNJ10,KCNJ11,KCNQ2,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LAMP2,LIG4,MAPT,MEF2C,MEIS2,MTR,MYCN,MYH3,MYO5A,MYO7A,NEXMIF,NCF2,NDP,NEFH,NEK1,NF1,NFIA,NFIX,HCN1,OCRL,GPR88,CHAMP1,OPA1,OPHN1,PAH,TREM2,PAK3,PAX6,PC,PDE4D,NLGN3,NALCN,A2ML1,GPSM2,PLEC,PLP1,PMP22,MAGEL2,FA2H,POLR2F,PPM1B,KANSL1,CEP41,PRKAR1B,PRPH,MASP1,CNNM2,NDUFS7,SAMD9,LAMA1,PIGG,PTCH1,PEX2,PEX5,TMEM231,QDPR,SH3TC2,FAT4,ROGDI,RBBP8,RET,REV3L,PRRT2,RFX5,RGR,KIF7,RLBP1,SETD5,TMLHE,ROM1,YY1AP1,ELP2,RPE65,ZC3H14,RYR1,SALL1,SBF1,ATXN2,SCN2A,SCN8A,PRCD,FOXRED1,SH3BP2,ARX,NTNG1,CNKSR2,ST3GAL3,SLC1A2,SLC1A3,PEX26,SLC6A1,SLC6A8,RAB3GAP1,SLC11A1,SMARCA4,DMRTC1,CDK5RAP2,SMARCE1,MBD5,SNRPN,UNC80,DOP1A,SON,MYT1L,SOX2,SOX3,TNIK,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,SPART,POGZ,SMOC1,ZC4H2,ELOVL4,KANK1,STXBP1,KLHL7,MLC1,FGD4,ABCC8,ARHGEF9,SYN1,SYP,ASTN2,TAC3,SEMA4A,DDHD2,CAMTA1,TAF6,CNTN2,TCF4,DMXL2,SATB2,RPGRIP1L,TCF12,WASHC4,NSD1,AHCYL2,ZFPM2,CRB1,AP4E1,GPR161,MTMR14,TK2,TLR4,ERCC6L2,KAT6B,TNNT1,TPM2,TPM3,TRH,TRIO,PDSS1,TRPS1,KCNE5,TSC1,TSC2,TUB,HIRA,HEPACAM,UBE3A,FRRS1L,DNAJC12,VLDLR,BEST1,WIPF1,CLIP2,NSD2,KLC2,PORCN,ZIC1,ZIC2,ZNF711,AGMO,FMN2,ZBTB16,TMEM237,POLR3H,FTSJ1,MFF,LMAN2L,TUBA1A,PCDH15,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,NLRP3,ADAMTS10,AAAS,AP3B2,GAN,LAS1L" Human Phenotype HP:0000570 Abnormal saccadic eye movements 9.33E-07 5.60E-03 1.40E-03 1.30E-02 34 75 "KLRC4,ALS2,ATP2B3,TPP1,FBXO7,DNAJC6,FGF14,NOP56,ERAP1,GJB1,GRM1,ELOVL5,TMEM240,IL12A,MAPT,MOBP,NTRK3,PDYN,APTX,PEX2,ATXN1,ATXN2,ATXN7,SCP2,SLC1A3,SLCO1A2,SNCA,VAMP1,RPGRIP1L,ATP13A2,TLR4,PIK3R5,TMEM237,GJC2" Human Phenotype HP:0011442 Abnormality of central motor function 1.17E-06 7.03E-03 1.41E-03 1.30E-02 417 1722 "ABAT,ADAR,KLRC4,ADCY5,ADD1,ADD3,SLC12A5,KIDINS220,PCDH19,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,LTBP4,ALK,KCNT1,AMPD2,AMT,CDC42BPA,ANK3,KCNAB2,ALS2,APP,SLC7A14,CASK,PDE8B,ASPA,PTCH2,ATM,ATP1A2,ATP1A3,ATP2B3,KIF1A,BBS2,BCS1L,FGF17,BLM,PROM1,BMPR1B,SYNJ1,ST3GAL5,SGCE,CACNA1G,NIPA1,CFAP410,CA4,CA8,CACNA1A,CACNA1B,CACNA1D,CACNB4,CAPN3,CBS,AIFM1,CD81,AP4M1,CDC42,LARGE1,CRLF1,ADGRG1,CHN1,RAB33A,TPP1,FBXO7,NIPBL,WHRN,RTTN,CP,CPS1,PNKD,PREPL,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,RUBCN,CX3CR1,RIPOR2,EARS2,MATR3,KIAA0586,DBT,DNAJC6,DCTN1,MAGI2,KLHL3,SACS,ARNT2,RAB39B,DMD,DMPK,DNM2,SLC12A6,ATN1,DSCAM,DTNA,DYRK1A,DNM1L,USH1C,WDPCP,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,AASS,EIF4G1,TNK2,BSCL2,ELN,EML1,C8orf37,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,CDHR1,APC2,ADGRV1,EYA1,REEP2,F8,ACSL4,TUBB3,TUBB4A,CEP78,FKTN,FGF12,FGF14,FGFR1,FGFR3,MAD2L2,PRKAG2,FHL1,FOXG1,SEC23B,NOP56,POMT1,APOPT1,STAMBP,TPK1,AP4B1,MEGF10,GAA,GABRA1,GABRA3,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,ERAP1,SEPT9,ATP8A2,INPP5K,GCK,TUBGCP4,GFAP,MMADHC,PPARGC1A,GJB1,GLDC,GLRB,GLUL,GNAL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,GUCY1A1,ATXN2L,KLF12,ELOVL5,AGBL5,TLX1,HPCA,CPT1C,ATCAY,IDH3B,NKD1,RBPJ,TMEM240,IL12A,IBA57,TUBB2B,KCNA1,KCNA2,KCNC1,KCND3,KCNJ5,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LAMP2,LIG4,LMO1,MAG,NAT8L,ZFYVE27,MAPT,MEF2C,MITF,MOBP,MOG,MSR1,CTNNA3,MTTP,MTR,MYCN,MYH7,MYO5A,MYO7A,NEXMIF,NDP,NEFH,NEK1,NF1,HCN1,NTRK3,OCRL,CHAMP1,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDYN,SERPINI1,NALCN,RETREG1,FTO,PLP1,PMP22,PSAT1,PMS2,MBOAT7,FA2H,POLG,POLR2F,PPP2R2B,CEP41,PRKAR1B,PRKCG,PRPH,CNNM2,NDUFS7,SAMD9,VPS13C,APTX,LAMA1,PIGG,PTCH1,PEX2,PEX5,TMEM231,QDPR,ATG16L1,ROGDI,RET,REV3L,PRRT2,RGR,KCTD17,KIF7,RLBP1,RNASEL,SETD5,ROM1,ELP2,RPE65,FBXW7,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN4B,SCN8A,PRCD,SCP2,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,ST3GAL3,NUBPL,SLC1A2,ZNF365,SLC1A3,PEX26,LIMS2,SLC6A1,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,CDK5RAP2,SNAP25,SNCB,SNCA,MBD5,LMBRD1,SNRPN,UNC80,DOP1A,SOX2,SOX3,SPATA7,ZCCHC24,SOX10,FNBP1,EMC1,ZNF423,SPTAN1,SPTB,KIF1B,SPART,STOX1,ZC4H2,ELOVL4,TTBK2,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,VPS13A,PLCB1,ASTN2,TACC1,SEMA4A,DDHD2,CAMTA1,TAF6,TAL1,TCF4,DMXL2,TRIM2,RPGRIP1L,WASHC4,SYNE1,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,ERCC6L2,CSMD1,TNNT1,PIK3R5,AMACR,TSC1,TSC2,TTPA,TUB,TMEFF2,HEPACAM,UBE3A,UCHL1,FRRS1L,DNAJC12,VLDLR,BEST1,WIPF1,CLIP2,NSD2,WRN,KLC2,XRCC4,AGMO,REEP1,TMEM237,POLR3H,MFF,PRDM8,TUBA1A,PCDH15,EPM2A,DOCK8,GJC2,RNF170,SNX14,AAAS,GAN,JPH3" Human Phenotype HP:0004305 Involuntary movements 1.42E-06 8.49E-03 1.42E-03 1.31E-02 203 750 "DGCR6,ADAR,ADCY5,SLITRK1,ADD1,PTCHD1,NLGN4X,HECW2,PCDH19,HACE1,CC2D2A,PLA2G6,CEP126,ALK,KCNT1,AMPD2,AMT,CDC42BPA,KCNAB2,APP,ASPA,PTCH2,ATM,ATP1A2,ATP1A3,STX16,ATP2B3,KIF1A,FGF17,SYNJ1,ST3GAL5,SGCE,CACNA1G,NIPA1,CFAP410,CA8,CACNA1A,CACNA1B,CACNA1D,CACNB4,AIFM1,ADGRG1,RAB33A,TPP1,FBXO7,NIPBL,CP,PNKD,TENM4,CTNND2,CX3CR1,HDAC4,MATR3,KIAA0586,DNAJC6,DCTN1,RAB39B,DNM1,DNM2,SLC12A6,ATN1,OPTN,EGFR,EIF4G1,BSCL2,ELN,GPHN,ERBB4,ERCC2,TUBB4A,FGF14,FGFR1,FOXG1,NOP56,APOPT1,STAMBP,GABRA1,GABRA3,GABRB3,GABRG2,GALC,SEPT9,ATP8A2,GCK,GFAP,PPARGC1A,GJB1,GLDC,GNAO1,GNAS,GRIK2,ADAMTS13,GRM1,HPCA,ATCAY,TMEM240,SLC6A17,TUBB2B,JAK1,JAK2,KCNA1,KCNA2,KCNC1,KCND3,KCNJ10,KCNMA1,KCNQ2,KCNQ3,KIF5A,LMO1,NAT8L,ZFYVE27,MAPT,MEF2C,MOBP,MTTP,MYCN,MYO5A,NEXMIF,NDP,NEFH,NEK1,NTRK2,NTRK3,OCRL,GPR88,CHAMP1,OPA1,PAH,TREM2,PAX6,PC,PDYN,NLGN3,SERPINI1,SNX10,PLP1,PMP22,FA2H,POLG,PPP2R2B,CEP41,PRPH,VPS13C,APTX,PEX2,QDPR,SH3TC2,PRRT2,KCTD17,MYH14,ELP2,RPE65,FBXW7,LRRK2,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,SCP2,SLC30A10,ARX,ST3GAL3,SLC6A1,SLC6A8,SLC20A2,SLCO1A2,SNCA,MBD5,SNRPN,DOP1A,SOX5,ZCCHC24,SOX10,SPTAN1,KIF1B,SPART,ELOVL4,STXBP1,VPS13A,PLCB1,CNTN2,RPGRIP1L,ATP13A2,TNFRSF1B,TNNT1,PIK3R5,AMACR,TTPA,UBE3A,UCHL1,FRRS1L,VLDLR,CLIP2,NSD2,REEP1,TMEM237,POLR3H,PRDM8,EPM2A,GJC2,JPH3" Human Phenotype HP:0001249 Intellectual disability 1.97E-06 1.18E-02 1.59E-03 1.47E-02 399 1644 "DGCR6,ARID1A,ADAR,KLRC4,SLC12A5,PTCHD1,KIDINS220,NLGN4X,HECW2,PCDH19,HACE1,NR0B1,CC2D2A,PLA2G6,LTBP4,KCNT1,BIN1,AMT,CDC42BPA,ANK1,ANK3,KCNAB2,APP,SLC7A14,CASK,ARHGDIA,CDK13,ASCL1,ASPA,PTCH2,ALDH4A1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,ALDH7A1,KIF1A,BBS2,MPDZ,BCS1L,FGF17,BLM,PROM1,SYNJ1,ST3GAL5,BTK,CFAP410,CA4,CA8,CACNA1A,CACNA1D,ISPD,CBS,AIFM1,AP4M1,LRBA,LARGE1,CRLF1,ADGRG1,CHM,CHN1,CHRNA4,RAB33A,CLCN4,NRXN1,NIPBL,ARHGEF6,RTTN,CPS1,PREPL,C2CD2,SH2B1,SEC24C,CNTNAP2,CTNND2,RUBCN,CX3CR1,CYBB,RIPOR2,FRMPD4,HDAC4,EARS2,MATR3,KIAA0586,DBT,DCC,DNAJC6,ZEB2,ZBTB24,KIAA0753,SACS,ARNT2,DLG2,DLG3,RAB39B,DMD,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,DPH1,DPP6,DSCAM,GNE,DTNA,MAMLD1,DYRK1A,ABCC9,USH1C,WDPCP,EDN1,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,OPTN,EGFR,AASS,BSCL2,ELN,EML1,C8orf37,EMX2,VPS13B,EPB41L1,ERBB4,ERCC2,CDHR1,APC2,ADGRV1,EYA1,CACNG2,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGF14,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,APOPT1,DLL3,AP4B1,GABRA1,GABRB3,GABRG2,GAD1,ZMYND11,B4GALNT1,ERAP1,ATP8A2,INPP5K,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,GFAP,MMADHC,GHR,PPARGC1A,KIRREL3,GK,GLDC,GLI2,GNAO1,GNAS,GPT2,GP1BB,PARD3B,GRIK2,GRIN1,GRM1,CIT,IL1RAPL1,MFSD2A,AP4S1,HBA1,MAN1B1,AGBL5,HNMT,HNRNPK,ZDHHC15,IDH3B,IGF1,RBPJ,TMEM240,IL12A,RIPPLY2,SLC6A17,TUBB2B,ITGA7,KCNA2,KCNH1,KCNJ5,KCNJ10,KCNJ11,KCNQ2,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LAMP2,LIG4,MAPT,MEF2C,MEIS2,MTR,MYCN,MYH3,MYO5A,MYO7A,NEXMIF,NCF2,NDP,NEFH,NEK1,NF1,NFIA,NFIX,HCN1,OCRL,GPR88,CHAMP1,OPA1,OPHN1,PAH,TREM2,PAK3,PAX6,PC,PDE4D,NLGN3,NALCN,A2ML1,GPSM2,PLP1,MAGEL2,FA2H,POLR2F,PPM1B,KANSL1,CEP41,PRKAR1B,PRPH,MASP1,CNNM2,NDUFS7,LAMA1,PIGG,PTCH1,PEX2,PEX5,TMEM231,QDPR,FAT4,ROGDI,RBBP8,RET,REV3L,PRRT2,RFX5,RGR,KIF7,RLBP1,SETD5,TMLHE,ROM1,YY1AP1,ELP2,RPE65,ZC3H14,SALL1,SBF1,ATXN2,SCN8A,PRCD,FOXRED1,SH3BP2,ARX,NTNG1,CNKSR2,ST3GAL3,SLC1A2,PEX26,SLC6A1,SLC6A8,RAB3GAP1,SLC11A1,SMARCA4,DMRTC1,CDK5RAP2,SMARCE1,MBD5,SNRPN,UNC80,DOP1A,SON,MYT1L,SOX2,SOX3,TNIK,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,SPART,POGZ,SMOC1,ZC4H2,ELOVL4,KANK1,STXBP1,KLHL7,MLC1,ABCC8,ARHGEF9,SYN1,SYP,ASTN2,TAC3,SEMA4A,DDHD2,CAMTA1,TAF6,CNTN2,TCF4,DMXL2,SATB2,RPGRIP1L,TCF12,WASHC4,NSD1,AHCYL2,ZFPM2,CRB1,AP4E1,GPR161,TK2,TLR4,ERCC6L2,KAT6B,TRH,PDSS1,TRPS1,KCNE5,TSC1,TSC2,TUB,HIRA,HEPACAM,UBE3A,FRRS1L,DNAJC12,VLDLR,BEST1,WIPF1,CLIP2,NSD2,PORCN,ZIC1,ZIC2,ZNF711,AGMO,FMN2,ZBTB16,TMEM237,POLR3H,FTSJ1,MFF,LMAN2L,TUBA1A,PCDH15,UBE3B,KAT6A,JMJD1C,RSPRY1,NLRP3,ADAMTS10,AAAS,AP3B2,GAN,LAS1L" Human Phenotype HP:0003808 Abnormal muscle tone 2.25E-06 1.35E-02 1.59E-03 1.47E-02 405 1674 "ABAT,DGCR6,ACADM,RBM10,ARID1A,ADAR,ADCY5,ADCY6,ADD1,ADD3,PTCHD1,KIDINS220,HECW2,PCDH19,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,LTBP4,KCNT1,AMPD2,BIN1,AMT,CDC42BPA,ANK3,CNTNAP1,KCNAB2,ALS2,PRX,CASK,CDK13,ASCL1,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,ATP2B3,ALDH7A1,KIF1A,BCS1L,FGF17,DST,SYNJ1,ST3GAL5,SGCE,CACNA1G,NIPA1,CFAP410,CA8,CACNA1A,CACNA1D,ISPD,AIFM1,AP4M1,LARGE1,CRLF1,CFL2,ADGRG1,RAB33A,CLCN4,NRXN1,COG1,FBXO7,NIPBL,CNTN1,COL11A2,RTTN,CP,CPS1,PREPL,C2CD2,SH2B1,CSF1R,SEC24C,VAC14-AS1,PNPLA8,CTNND2,CX3CR1,RIPOR2,HDAC4,EARS2,MATR3,KIAA0586,DBT,DNAJC6,DCTN1,ZEB2,B3GAT3,KIAA0753,SACS,ARNT2,DLG3,RAB39B,DMD,DNM1,DMPK,MED12,TRAPPC9,DNM2,SLC12A6,DSCAM,GNE,DTNA,DYRK1A,DNM1L,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,OPTN,AASS,EIF4G1,BSCL2,ELN,EML1,DCTN4,EMX2,VPS13B,EPB41,COQ7,GPHN,ERBB4,ERCC2,APC2,EYA1,REEP2,WAC,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGFR1,FGFR3,MAD2L2,FOXG1,POMT1,APOPT1,STAMBP,TPK1,AP4B1,MEGF10,GAA,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,ATP8A2,INPP5K,GCK,TUBGCP4,TUBA8,AHDC1,GFAP,MMADHC,PPARGC1A,GJB1,GLDC,GLI2,GLRB,GLUL,GPT2,GP1BB,PCLO,PARD3B,GRIN2D,GRM1,PRDM5,CIT,MFSD2A,AP4S1,HBA1,HNRNPK,ZDHHC15,CPT1C,ATCAY,GAREM2,RBPJ,TMEM240,IBA57,TUBB2B,ITGA7,KCNA1,KCNB1,KCND3,KCNH1,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LIFR,LIG4,MAG,NAT8L,ZFYVE27,MAPT,MEF2C,MITF,MOBP,MSR1,MTTP,MTR,MYH7,MYO5A,NEXMIF,NDP,NEFH,NEK1,NF1,NFIA,NFIX,NTRK3,DDR2,OCRL,CHAMP1,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDE4D,NALCN,A2ML1,RETREG1,FTO,PLP1,PMP22,PSAT1,PMS2,MAGEL2,MBOAT7,FA2H,POLG,POLR2F,PPM1B,KANSL1,CEP41,PRPH,NDUFS7,VPS13C,LAMA1,WDR25,PIGG,PTCH1,BDNF-AS,PEX2,PEX5,TMEM231,QDPR,FAT4,ROGDI,RET,REV3L,PRRT2,KCTD17,KIF7,RNASEL,SETD5,ALG9,ELP2,RPE65,LRRK2,MEG3,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN4B,SCN8A,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,ST3GAL3,NUBPL,SLC1A2,SLC1A3,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,SMARCA4,DMRTC1,SMARCE1,SNCB,SNCA,MBD5,LMBRD1,SNRPN,UNC80,DOP1A,SON,SOX2,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,SPTAN1,SPTB,IQSEC2,SPART,POGZ,ZC4H2,ELOVL4,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,VPS13A,PLCB1,DDHD2,CAMTA1,TAF6,ALG1,TCF4,SATB2,TRIM2,RPGRIP1L,WASHC4,SZT2,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,THRA,TK2,DDHD1,ERCC6L2,CSMD1,KAT6B,TNNT1,TPM2,TPM3,AMACR,TRPS1,KCNE5,TTPA,TUBB2A,TMEFF2,HIRA,HEPACAM,UBE3A,UCHL1,FRRS1L,DNAJC12,VLDLR,CLIP2,NSD2,KLC2,LGI4,ZIC1,AGMO,FMN2,REEP1,TMEM237,POLR3H,WNK1,MFF,PRDM8,TUBA1A,PDSS2,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,SNX14,AAAS,AP3B2,GAN,LAS1L,JPH3" Human Phenotype HP:0000750 Delayed speech and language development 2.38E-06 1.43E-02 1.59E-03 1.47E-02 121 407 "ARID1A,KIDINS220,NLGN4X,PLA2G6,LTBP4,AMT,KCNAB2,CASK,CDK13,ASPA,ALDH7A1,BBS2,BMPR1B,ST3GAL5,BTK,CA8,AIFM1,RAB33A,TPP1,NIPBL,COL11A2,CP,SH2B1,VAC14-AS1,CTNND2,EARS2,ZEB2,DLG3,DMD,DNM1,DSCAM,GNE,DTNA,DYRK1A,EDN1,AASS,BSCL2,ELN,C8orf37,ERCC2,WAC,TUBB4A,FKTN,GORAB,FGF12,FGFR1,FOXG1,AFF2,POMT1,AP4B1,ZMYND11,ATP8A2,GATM,SRCAP,GLDC,GNAO1,GPT2,MFSD2A,HNMT,ZDHHC15,TUBB2B,KCNJ10,KIF5C,L1CAM,LIG4,MAPT,MEF2C,MEIS2,MOBP,NEXMIF,NF1,NFIA,NFIX,OPHN1,PAK3,PDE4D,NLGN3,NALCN,PIK3R1,PLP1,KANSL1,LAMA1,PIGG,TMEM231,REV3L,SETD5,TMLHE,ELP2,ARX,SLC6A8,SLCO1A2,SMARCE1,MBD5,SNRPN,UNC80,MYT1L,TNIK,SOX5,EMC1,IQSEC2,ZC4H2,STXBP1,ASTN2,CAMTA1,TAF6,TCF4,SATB2,NSD1,KAT6B,TRIO,TRPS1,UBE3A,FRRS1L,DNAJC12,VLDLR,CLIP2,XRCC4,FTSJ1,MFF,AP3B2,LAS1L" Human Phenotype HP:0002167 Neurological speech impairment 2.92E-06 1.75E-02 1.75E-03 1.62E-02 216 814 "ADAR,KLRC4,ADCY5,SLITRK1,ADD3,PLA2G6,BIN1,AMT,KCNAB2,ALS2,CASK,PDE8B,ATM,ATP1A2,ATP1A3,STX16,ATP2B3,ALDH7A1,BBS2,BCS1L,FGF17,SYNJ1,ST3GAL5,CACNA1G,CFAP410,CA8,CACNA1A,CACNA1B,CACNB4,LARGE1,ADGRG1,TPP1,FBXO7,NIPBL,RTTN,CP,PNKD,SH2B1,CSF1R,SEC24C,PNPLA8,CTNND2,RUBCN,EARS2,MATR3,DNAJC6,DCTN1,ZEB2,SACS,RAB39B,DNM1,MED12,DTNA,WDPCP,OPTN,EGFR,BSCL2,ELN,C8orf37,VPS13B,ERBB4,ERCC2,APC2,EYA1,ACSL4,TUBB4A,FKTN,FGF12,FGF14,FGFR1,FGFR3,FOXG1,NOP56,POMT1,TPK1,AP4B1,GAA,GABRG2,B4GALNT1,ERAP1,SEPT9,ATP8A2,INPP5K,SRCAP,GFAP,PPARGC1A,GJB1,GLDC,GNAL,GNAO1,GNAS,GPT2,GP1BB,GRM1,MFSD2A,HBA1,ELOVL5,HNRNPK,HPCA,ZDHHC15,ATCAY,TMEM240,IL12A,TUBB2B,JAK2,KCNA1,KCND3,KCNJ10,KCNQ2,KCNQ3,KIF5C,L1CAM,MAG,MAPT,MEF2C,MOBP,MYH3,NEXMIF,NEFH,NEK1,NF1,OCRL,GPR88,OPHN1,TREM2,PAX6,PDYN,SERPINI1,NALCN,PIK3R1,A2ML1,PLEC,PLP1,PMS2,FA2H,POLG,PPP2R2B,KANSL1,PRKAR1B,PRKCG,PRPH,CNNM2,NDUFS7,APTX,PEX2,TMEM231,REV3L,PRRT2,KCTD17,SETD5,LRRK2,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,SLC30A10,FOXRED1,ARX,SLC1A3,SLC6A1,SLC20A2,SLCO1A2,SMARCE1,SNAP25,SNCA,MBD5,UNC80,DOP1A,ZCCHC24,SOX10,IQSEC2,SPART,ZC4H2,ELOVL4,TTBK2,STXBP1,VAMP1,VPS13A,ASTN2,TACC1,DDHD2,CAMTA1,TAF6,TCF4,DMXL2,SATB2,SYNE1,SLC19A3,NSD1,ATP13A2,TK2,TLR4,KAT6B,PIK3R5,TRIO,TTPA,HIRA,HEPACAM,UBE3A,FRRS1L,VLDLR,CLIP2,KLC2,XRCC4,FMN2,REEP1,MFF,PRDM8,GJC2,JMJD1C,AAAS,AP3B2,GAN,LAS1L,JPH3" Human Phenotype HP:0007359 Focal-onset seizure 4.18E-06 2.51E-02 2.28E-03 2.12E-02 46 120 "SLC12A5,PCDH19,KCNT1,AMT,CACNA1D,CACNB4,LGI1,CHRNA4,C2CD2,PNPLA8,CX3CR1,RIPOR2,DNM1,DSCAM,GABRA1,GABRB3,GABRG2,GLDC,PARD3B,AP4S1,KCNQ2,KCNQ3,STXBP5,LAMA2,MBOAT7,POLG,RELN,LAMA1,PRRT2,STX1B,SCN2A,SCN8A,SLC11A1,STXBP1,PLCB1,SYN1,CNTN2,SZT2,AHCYL2,ZFPM2,TSC1,TSC2,UBE3A,AGMO,FMN2,EPM2A" Human Phenotype HP:0001273 Abnormal corpus callosum morphology 6.22E-06 3.73E-02 3.11E-03 2.88E-02 138 485 "ABAT,RBM10,ARID1A,KIDINS220,HACE1,WDR35,CC2D2A,KCNT1,AMPD2,AMT,KCNAB2,APC,CDK13,KIF1A,SYNJ1,ISPD,AIFM1,AP4M1,LARGE1,NIPBL,RTTN,EARS2,KIAA0586,DCC,ZEB2,KIAA0753,ARNT2,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,EDN3,EDNRB,ATL1,SEMA3D,EML1,EMX2,VPS13B,ERCC2,APC2,WAC,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,TMEM107,STAMBP,AP4B1,GABRB1,GABRB3,ATP8A2,AHDC1,GFAP,GLDC,GLI2,GLUL,GNAO1,GPT2,PCLO,CIT,MFSD2A,RBPJ,DOCK7,IBA57,TUBB2B,KCNQ2,KIF2A,KIF5C,L1CAM,LIG4,MAG,MEF2C,MID1,NEXMIF,NEK1,NFIA,NFIX,TREM2,PAX6,PDYN,GPSM2,PSAT1,PMS2,PRRX1,FA2H,KANSL1,CEP41,PIGG,PTCH1,TMEM260,TMEM231,FAT4,RET,KIF7,SALL1,SCN4B,ARX,FUZ,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SMARCA4,CDK5RAP2,SMARCE1,UNC80,SON,SOX2,SOX3,SOX11,EMC1,ZNF423,SPTAN1,POGZ,STXBP1,DDHD2,TCF4,RPGRIP1L,SZT2,NSD1,ZFPM2,KAT6B,TSC1,TSC2,TUBB2A,NSD2,PORCN,ZIC1,TMEM237,POLR3H,TUBA1A,GJC2,AP3B2" Human Phenotype HP:0011182 Interictal epileptiform activity 6.74E-06 4.04E-02 3.11E-03 2.89E-02 38 94 "AMT,KCNAB2,KIF1A,CACNB4,DNM1,EEF1A2,FGF12,GABRA1,GABRB1,GABRB3,GABRG2,GCK,GLDC,GNAO1,GRIN2D,DOCK7,KCNB1,KCNJ11,KCNMA1,KCNQ2,KCNQ3,NEXMIF,NF1,PIGG,ROGDI,SCN2A,ARX,ST3GAL3,SLC1A2,SLC6A1,SPTAN1,IQSEC2,STXBP1,ABCC8,PLCB1,TUBB2A,MFF,AP3B2" Human Phenotype HP:0001250 Seizures 7.94E-06 4.76E-02 3.40E-03 3.16E-02 366 1508 "ABAT,DGCR6,ACADM,ARID1A,ADAR,KLRC4,ADD1,ADD3,SLC12A5,NLGN4X,HECW2,PCDH19,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,KCNT1,AMPD2,AMT,CDC42BPA,ANK1,ANK2,ANK3,KCNAB2,APP,SLC7A14,CASK,ASCL1,ASPA,ALDH4A1,ATM,ATP1A2,ATP1A3,STX16,ATP2A2,ALDH7A1,KIF1A,BBS2,MPDZ,BCS1L,FGF17,PROM1,SYNJ1,ST3GAL5,NIPA1,CA4,CA8,CACNA1A,CACNA1D,CACNB4,CALM1,ISPD,CBS,KRIT1,AIFM1,AP4M1,LGI1,LARGE1,CRLF1,ADGRG1,CHN1,CHRNA4,CHRNB2,RAB33A,TPP1,NIPBL,RTTN,CPS1,PREPL,C2CD2,SH2B1,SEC24C,CNTNAP2,PNPLA8,RUBCN,CX3CR1,RIPOR2,FRMPD4,HDAC4,EARS2,KIAA0586,DBT,DNAJC6,ZEB2,ARNT2,DLG3,RAB39B,DNM1,MED12,TRAPPC9,CDON,DNM2,SLC12A6,ATN1,DSCAM,GNE,DTNA,DYRK1A,DNM1L,ABCC9,EDN3,EDNRB,EEF1A2,SEMA3D,EGFR,AASS,BSCL2,EML1,C8orf37,EMX2,VPS13B,GPHN,ERBB2,ERCC2,CDHR1,APC2,ADGRV1,F8,WAC,TUBB3,TUBB4A,FKTN,STRADA,FGF12,FGFR1,FGFR3,PRKAG2,FOXG1,SEC23B,POMT1,APOPT1,STAMBP,TPK1,AP4B1,MEGF10,GAA,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,TRAF3IP2,GAD1,GALC,ERAP1,ATP8A2,INPP5K,GCK,TUBGCP4,TUBA8,GFAP,MMADHC,GK,GLDC,GLI2,GLUL,GNAO1,GNAS,GPT2,GP1BB,PCLO,PARD3B,GRIK2,GRIN2D,GRM1,CIT,IL1RAPL1,MFSD2A,AP4S1,GUCY1A1,HBA1,MAN1B1,AGBL5,ZDHHC15,IDH3B,RBPJ,IL12A,TUBB2B,JAK2,KCNA1,KCNA2,KCNB1,KCNC1,KCNH1,KCNJ10,KCNJ11,KCNMA1,KCNQ2,KCNQ3,KIF2A,KIF5C,STXBP5,L1CAM,LAMA2,LIG4,NAT8L,MAPT,MEF2C,MEIS2,MOG,MTR,MYH3,MYO5A,NEXMIF,NDP,NF1,NFIA,HCN1,NTRK3,OCRL,OPHN1,PAH,TREM2,PAK3,PC,PCSK1,PDE4D,NLGN3,SERPINI1,NALCN,A2ML1,GPSM2,FTO,PLP1,PSAT1,PMS2,MAGEL2,MBOAT7,FA2H,POLG,POLR2F,PPM1B,KANSL1,CEP41,RELN,CNNM2,NDUFS7,SAMD9,LAMA1,WDR25,PIGG,PTCH1,BDNF-AS,PEX2,PEX5,TMEM231,QDPR,ROGDI,RET,PRRT2,RGR,KIF7,RLBP1,SETD5,TMLHE,ALG9,ROM1,RPE65,MEG3,STX1B,SCN2A,SCN4B,SCN8A,PRCD,FOXRED1,ARX,NTNG1,ST3GAL3,NUBPL,SLC1A2,ZNF365,SLC1A3,PEX26,SLC6A1,SLC6A8,RAB3GAP1,SLC11A1,SLC20A2,SMARCA4,DMRTC1,SMARCE1,MBD5,LMBRD1,SNRPN,UNC80,SON,SOX2,SOX3,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,POGZ,STOX1,ZC4H2,ELOVL4,STXBP1,KLHL7,MLC1,ABCC8,ARHGEF9,VPS13A,PLCB1,SYN1,SYP,TACC1,SEMA4A,ROBO3,TAF6,ALG1,CNTN2,TCF4,SATB2,RPGRIP1L,SZT2,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,GPR161,TK2,TLR4,CSMD1,KAT6B,TRIO,AMACR,TRPS1,TSC1,TSC2,TUB,TUBB2A,TMEFF2,HIRA,HEPACAM,UBE3A,VLDLR,BEST1,NSD2,LGI4,AGMO,FMN2,CRB2,TMEM237,POLR3H,FTSJ1,MFF,PRDM8,LMAN2L,TUBA1A,PDSS2,EPM2A,KAT6A,GJC2,JMJD1C,SNX14,AAAS,AP3B2,LAS1L" Human Phenotype HP:0001284 Areflexia 9.48E-06 5.69E-02 3.79E-03 3.52E-02 67 201 "PLEKHG5,ADCY6,PLA2G6,BIN1,CNTNAP1,PRX,ATP1A3,KIF1A,DST,ISPD,AIFM1,LARGE1,CFL2,RAB33A,CNTN1,CX3CR1,DCAF8,SACS,DNM2,SLC12A6,GNE,DNM1L,FKTN,FHL1,POMT1,MEGF10,GAA,SEPT9,INPP5K,GJB1,LAMA2,LIFR,MAG,MTTP,OCRL,RETREG1,PMP22,POLG,POLR2F,APTX,LAMA1,PEX2,PEX5,MYH14,RYR1,SBF1,ATXN1,PEX26,SNAP25,SOX10,KIF1B,ZC4H2,FGD4,VPS13A,ASTN2,ALG1,TRIM2,MTMR14,PIK3R5,PDSS1,TTPA,LGI4,REEP1,POLR3H,WNK1,RNF170,GAN" Human Phenotype HP:0007370 Aplasia/Hypoplasia of the corpus callosum 1.48E-05 8.86E-02 5.54E-03 5.14E-02 132 467 "ABAT,ARID1A,KIDINS220,HACE1,WDR35,CC2D2A,KCNT1,AMPD2,AMT,KCNAB2,APC,CDK13,KIF1A,SYNJ1,ISPD,AIFM1,AP4M1,LARGE1,NIPBL,EARS2,KIAA0586,DCC,ZEB2,KIAA0753,ARNT2,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,EDN3,EDNRB,ATL1,SEMA3D,EML1,EMX2,ERCC2,APC2,WAC,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,TMEM107,STAMBP,AP4B1,GABRB1,GABRB3,AHDC1,GFAP,GLDC,GLI2,GLUL,GNAO1,GPT2,PCLO,CIT,MFSD2A,RBPJ,DOCK7,IBA57,TUBB2B,KCNQ2,KIF2A,KIF5C,L1CAM,LIG4,MEF2C,MID1,NEXMIF,NEK1,NFIA,NFIX,TREM2,PAX6,PDYN,GPSM2,PSAT1,PMS2,PRRX1,FA2H,KANSL1,CEP41,PIGG,PTCH1,TMEM260,TMEM231,FAT4,RET,KIF7,SALL1,SCN4B,ARX,FUZ,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SMARCA4,CDK5RAP2,SMARCE1,UNC80,SON,SOX2,SOX3,SOX11,EMC1,ZNF423,SPTAN1,POGZ,STXBP1,DDHD2,TCF4,RPGRIP1L,NSD1,ZFPM2,KAT6B,TSC1,TSC2,TUBB2A,NSD2,PORCN,ZIC1,TMEM237,POLR3H,TUBA1A,GJC2,AP3B2" Human Phenotype HP:0002500 Abnormality of the cerebral white matter 1.93E-05 1.16E-01 6.47E-03 6.00E-02 154 563 "ABAT,RBM10,ARID1A,KIDINS220,HACE1,WDR35,CC2D2A,KCNT1,AMPD2,AMT,KCNAB2,APC,CDK13,KIF1A,SYNJ1,ISPD,AIFM1,AP4M1,LARGE1,NIPBL,RTTN,CSF1R,EARS2,KIAA0586,DCC,ZEB2,KIAA0753,ARNT2,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,EDN3,EDNRB,ATL1,SEMA3D,EML1,EMX2,VPS13B,ERCC2,APC2,WAC,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,TMEM107,STAMBP,AP4B1,GABRB1,GABRB3,GALC,ATP8A2,AHDC1,GFAP,GJB1,GLDC,GLI2,GLUL,GNAO1,GPT2,PCLO,CIT,MFSD2A,RBPJ,DOCK7,IBA57,TUBB2B,KCNQ2,KIF2A,KIF5C,L1CAM,LAMA2,LIG4,MAG,MAPT,MEF2C,MID1,NEXMIF,NDP,NEK1,NFIA,NFIX,OCRL,PAH,TREM2,PAX6,PC,PDYN,GPSM2,PLP1,PSAT1,PMS2,PRRX1,FA2H,POLG,KANSL1,CEP41,LAMA1,PIGG,PTCH1,TMEM260,PEX2,PEX5,TMEM231,FAT4,RET,KIF7,SALL1,SCN4B,ARX,FUZ,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SMARCA4,CDK5RAP2,SMARCE1,UNC80,SON,SOX2,SOX3,SOX11,EMC1,ZNF423,SPTAN1,POGZ,STXBP1,MLC1,DDHD2,TCF4,RPGRIP1L,SZT2,NSD1,ZFPM2,KAT6B,TSC1,TSC2,TUBB2A,HEPACAM,NSD2,PORCN,ZIC1,TMEM237,POLR3H,TUBA1A,GJC2,AP3B2" Human Phenotype HP:0002540 Inability to walk 1.96E-05 1.18E-01 6.47E-03 6.00E-02 28 64 "ADAR,SLC12A5,HACE1,LTBP4,KIF1A,SYNJ1,VAC14-AS1,DNAJC6,DMD,DNM1,ERBB4,STRADA,FGF12,POMT1,ATP8A2,BVES,MFSD2A,AP4S1,SLC6A17,KCNQ2,LAMA2,MEF2C,MBOAT7,LAMA1,SLC19A3,TK2,MFF,SNX14" Human Phenotype HP:0001311 Abnormal nervous system electrophysiology 2.05E-05 1.23E-01 6.47E-03 6.00E-02 165 611 "DGCR6,ARID1A,PLEKHG5,ADD1,NLGN4X,HECW2,PCDH19,WDR35,CC2D2A,PLA2G6,CEP126,AMT,KCNAB2,AMER3,PRX,ASPA,ATP1A2,ALDH7A1,KIF1A,BCS1L,MTMR2,CFAP410,CACNA1A,CACNA2D1,CACNB4,ISPD,AIFM1,LARGE1,RAB33A,NRXN3,NRXN1,TPP1,RTTN,SH2B1,ARHGEF10,CTNND2,CX3CR1,DOCK4,KATNAL2,DCAF8,MATR3,ZNF804A,SACS,DLG2,DMD,DNM1,DMPK,DNM2,SLC12A6,DPH1,EDNRB,EEF1A2,OPTN,AASS,EMX2,VPS13B,ERBB4,ERCC2,APC2,FKTN,FGF12,FGFR1,FOXG1,POMT1,TMEM107,GAA,GABRA1,GABRB1,GABRB3,GABRG2,GALC,GCK,GFAP,PPARGC1A,GJB1,GLDC,GNAO1,GRIN2D,HTR2A,RBPJ,DOCK7,KCNB1,KCNJ11,KCNMA1,KCNQ2,KCNQ3,MAPT,MOBP,MYH3,NEXMIF,NDP,NEFH,NEK1,NF1,NOS1,OCRL,OPA1,PAH,TREM2,PAX6,NLGN3,NALCN,RETREG1,PLEC,FTO,PMP22,PSAT1,POLR2F,PRPH,RELN,PIGG,PEX2,PEX5,TMEM231,SH3TC2,ROGDI,PRRT2,KIF7,TMLHE,SBF1,ATXN1,ATXN2,SCN2A,SCN8A,ARX,NTNG1,ST3GAL3,SLC1A2,PEX26,SLC6A1,SLCO1A2,SMARCA4,SMARCE1,MBD5,SOX10,SOX11,SPTAN1,KIF1B,IQSEC2,NPAS3,STXBP1,FGD4,ABCC8,PLCB1,SYN2,CNTN2,RPGRIP1L,SZT2,NSD1,CSMD1,PIK3R5,TSC1,TSC2,TUBB2A,UBE3A,VIPR2,NSD2,ZIC1,REEP1,TMEM237,WNK1,MFF,GJC2,NLRP3,AP3B2" Human Phenotype HP:0011198 EEG with generalized epileptiform discharges 2.36E-05 1.42E-01 7.09E-03 6.58E-02 35 88 "AMT,KCNAB2,KIF1A,CACNB4,EEF1A2,FGF12,GABRA1,GABRB1,GABRB3,GABRG2,GCK,GLDC,GNAO1,GRIN2D,DOCK7,KCNB1,KCNJ11,KCNMA1,KCNQ2,KCNQ3,NEXMIF,NF1,ROGDI,SCN2A,ARX,ST3GAL3,SLC1A2,SLC6A1,SPTAN1,STXBP1,ABCC8,PLCB1,TUBB2A,MFF,AP3B2" Human Phenotype HP:0002061 Lower limb spasticity 2.53E-05 1.52E-01 7.22E-03 6.70E-02 44 120 "KIDINS220,HACE1,AMPD2,ALS2,KIF1A,NIPA1,CACNA1D,AP4M1,FBXO7,EDNRB,ATL1,BSCL2,REEP2,AP4B1,B4GALNT1,INPP5K,AP4S1,CPT1C,IBA57,KIF5A,L1CAM,MAG,ZFYVE27,PLP1,FA2H,POLG,POLR2F,PRRT2,SLC30A10,ARX,SNCA,SOX10,SPART,STXBP1,VAMP1,DDHD2,ATP13A2,AP4E1,DDHD1,UCHL1,KLC2,REEP1,GJC2,GAN" Human Phenotype HP:0000322 Short philtrum 3.20E-05 1.92E-01 8.73E-03 8.10E-02 44 121 "ARID1A,CDK13,AP4M1,CDC42,NOG,NIPBL,SEC24C,CTNND2,MED12,TRAPPC9,VPS13B,FGFR1,AP4B1,SRCAP,FREM1,TXNL4A,GLI2,GP1BB,AP4S1,MAN1B1,DOCK7,MEF2C,MEIS2,NEXMIF,NFIX,CHAMP1,OPHN1,KIF7,RAB3GAP1,SMARCA4,SMARCE1,UNC80,SON,SOX11,EMC1,POGZ,TCF4,NSD1,AP4E1,HIRA,NSD2,TMEM237,UBE3B,JMJD1C" Human Phenotype HP:0001319 Neonatal hypotonia 3.76E-05 2.26E-01 9.81E-03 9.10E-02 53 155 "BIN1,AMT,CASK,ATP2B3,BCS1L,DST,AP4M1,CNTN1,PREPL,SH2B1,CTNND2,EARS2,DMPK,MED12,SLC12A6,EEF1A2,VPS13B,FGFR1,FOXG1,AP4B1,MEGF10,TUBA8,GJB1,GLDC,PCLO,PRDM5,ITGA7,LAMA2,MAG,MYH7,NEXMIF,OCRL,MAGEL2,POLR2F,LAMA1,PEX2,PEX5,RYR1,ARX,PEX26,SLC6A8,SNRPN,SOX10,CAMTA1,TAF6,NSD1,AP4E1,ERCC6L2,TPM2,TPM3,UBE3A,PDSS2,KAT6A" Human Phenotype HP:0030178 Abnormality of central nervous system electrophysiology 4.35E-05 2.61E-01 1.09E-02 1.01E-01 130 468 "DGCR6,ARID1A,ADD1,NLGN4X,HECW2,PCDH19,WDR35,CC2D2A,AMT,KCNAB2,AMER3,ASPA,ATP1A2,ALDH7A1,KIF1A,BCS1L,MTMR2,CACNA1A,CACNA2D1,CACNB4,ISPD,LARGE1,NRXN3,NRXN1,RTTN,SH2B1,CTNND2,CX3CR1,DOCK4,KATNAL2,ZNF804A,DLG2,DMD,DNM1,SLC12A6,DPH1,EDNRB,EEF1A2,AASS,EMX2,VPS13B,ERCC2,APC2,FKTN,FGF12,FGFR1,FOXG1,POMT1,TMEM107,GAA,GABRA1,GABRB1,GABRB3,GABRG2,GALC,GCK,GFAP,GLDC,GNAO1,GRIN2D,HTR2A,RBPJ,DOCK7,KCNB1,KCNJ11,KCNMA1,KCNQ2,KCNQ3,MAPT,MYH3,NEXMIF,NDP,NEK1,NF1,OCRL,OPA1,PAH,TREM2,PAX6,NLGN3,NALCN,FTO,PSAT1,POLR2F,RELN,PIGG,PEX2,PEX5,TMEM231,SH3TC2,ROGDI,PRRT2,KIF7,TMLHE,SCN2A,SCN8A,ARX,NTNG1,ST3GAL3,SLC1A2,PEX26,SLC6A1,SMARCA4,SMARCE1,MBD5,SOX10,SOX11,SPTAN1,IQSEC2,NPAS3,STXBP1,ABCC8,PLCB1,SYN2,CNTN2,RPGRIP1L,SZT2,NSD1,CSMD1,TSC1,TSC2,TUBB2A,UBE3A,VIPR2,NSD2,ZIC1,TMEM237,MFF,NLRP3,AP3B2" Human Phenotype HP:0002493 Upper motor neuron dysfunction 4.89E-05 2.93E-01 1.12E-02 1.04E-01 297 1213 "ABAT,ADAR,KLRC4,ADCY5,ADD1,ADD3,SLC12A5,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,KCNT1,AMPD2,AMT,CDC42BPA,ANK3,KCNAB2,ALS2,SLC7A14,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BBS2,BCS1L,FGF17,PROM1,SYNJ1,ST3GAL5,CACNA1G,NIPA1,CFAP410,CA4,CA8,CACNA1A,CACNA1D,CBS,AIFM1,AP4M1,LARGE1,CRLF1,ADGRG1,RAB33A,TPP1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,RUBCN,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,SLC12A6,ATN1,DSCAM,DTNA,DNM1L,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,AASS,EIF4G1,BSCL2,ELN,EML1,C8orf37,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,CDHR1,APC2,EYA1,REEP2,F8,ACSL4,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,NOP56,POMT1,STAMBP,TPK1,AP4B1,GABRA3,CHL1,GAD1,GALC,B4GALNT1,ERAP1,ATP8A2,INPP5K,TUBGCP4,GFAP,PPARGC1A,GJB1,GLDC,GLRB,GLUL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,GUCY1A1,AGBL5,CPT1C,IDH3B,RBPJ,TMEM240,IL12A,IBA57,TUBB2B,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,LIG4,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NF1,NTRK3,OCRL,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDYN,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,MBOAT7,FA2H,POLG,POLR2F,PPP2R2B,PRKCG,PRPH,CNNM2,NDUFS7,SAMD9,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RGR,RLBP1,RNASEL,SETD5,ROM1,ELP2,RPE65,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,PRCD,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,SLC1A3,PEX26,LIMS2,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,CDK5RAP2,SNCB,SNCA,UNC80,SOX2,SOX3,SPATA7,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,TTBK2,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,TACC1,SEMA4A,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,CSMD1,TNNT1,PIK3R5,AMACR,TSC1,TSC2,TTPA,TUB,TMEFF2,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,BEST1,CLIP2,WRN,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,DOCK8,GJC2,RNF170,SNX14,AAAS,GAN,JPH3" Human Phenotype HP:0007256 Abnormal pyramidal sign 4.89E-05 2.93E-01 1.12E-02 1.04E-01 297 1213 "ABAT,ADAR,KLRC4,ADCY5,ADD1,ADD3,SLC12A5,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,KCNT1,AMPD2,AMT,CDC42BPA,ANK3,KCNAB2,ALS2,SLC7A14,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BBS2,BCS1L,FGF17,PROM1,SYNJ1,ST3GAL5,CACNA1G,NIPA1,CFAP410,CA4,CA8,CACNA1A,CACNA1D,CBS,AIFM1,AP4M1,LARGE1,CRLF1,ADGRG1,RAB33A,TPP1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,RUBCN,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,SLC12A6,ATN1,DSCAM,DTNA,DNM1L,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,AASS,EIF4G1,BSCL2,ELN,EML1,C8orf37,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,CDHR1,APC2,EYA1,REEP2,F8,ACSL4,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,NOP56,POMT1,STAMBP,TPK1,AP4B1,GABRA3,CHL1,GAD1,GALC,B4GALNT1,ERAP1,ATP8A2,INPP5K,TUBGCP4,GFAP,PPARGC1A,GJB1,GLDC,GLRB,GLUL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,GUCY1A1,AGBL5,CPT1C,IDH3B,RBPJ,TMEM240,IL12A,IBA57,TUBB2B,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,LIG4,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NF1,NTRK3,OCRL,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDYN,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,MBOAT7,FA2H,POLG,POLR2F,PPP2R2B,PRKCG,PRPH,CNNM2,NDUFS7,SAMD9,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RGR,RLBP1,RNASEL,SETD5,ROM1,ELP2,RPE65,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,PRCD,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,SLC1A3,PEX26,LIMS2,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,CDK5RAP2,SNCB,SNCA,UNC80,SOX2,SOX3,SPATA7,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,TTBK2,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,TACC1,SEMA4A,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,CSMD1,TNNT1,PIK3R5,AMACR,TSC1,TSC2,TTPA,TUB,TMEFF2,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,BEST1,CLIP2,WRN,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,DOCK8,GJC2,RNF170,SNX14,AAAS,GAN,JPH3" Human Phenotype HP:0010864 "Intellectual disability, severe" 5.05E-05 3.03E-01 1.12E-02 1.04E-01 79 258 "CC2D2A,ASPA,KIF1A,CACNA1D,ISPD,AP4M1,LARGE1,NRXN1,NIPBL,PREPL,CTNND2,DNM1,DMPK,TRAPPC9,DSCAM,DYRK1A,EDN3,EDNRB,EEF1A2,SEMA3D,ELN,EML1,ERCC2,ACSL4,FKTN,FGFR3,FOXG1,POMT1,AP4B1,GABRB3,GCK,CIT,MFSD2A,AP4S1,HBA1,HNMT,SLC6A17,KCNH1,KCNJ11,L1CAM,MEF2C,OCRL,PAH,PC,A2ML1,PEX2,PEX5,TMEM231,ROGDI,RET,KIF7,SETD5,ARX,PEX26,RAB3GAP1,CDK5RAP2,MBD5,SNRPN,ZNF423,SPTAN1,SMOC1,STXBP1,ABCC8,ARHGEF9,TCF4,SATB2,AP4E1,KAT6B,KCNE5,TSC1,TSC2,UBE3A,CLIP2,NSD2,ZIC1,TMEM237,POLR3H,LMAN2L,TUBA1A" Human Phenotype HP:0002062 Morphological abnormality of the pyramidal tract 5.64E-05 3.38E-01 1.17E-02 1.08E-01 297 1215 "ABAT,ADAR,KLRC4,ADCY5,ADD1,ADD3,SLC12A5,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,KCNT1,AMPD2,AMT,CDC42BPA,ANK3,KCNAB2,ALS2,SLC7A14,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BBS2,BCS1L,FGF17,PROM1,SYNJ1,ST3GAL5,CACNA1G,NIPA1,CFAP410,CA4,CA8,CACNA1A,CACNA1D,CBS,AIFM1,AP4M1,LARGE1,CRLF1,ADGRG1,RAB33A,TPP1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,RUBCN,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,SLC12A6,ATN1,DSCAM,DTNA,DNM1L,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,AASS,EIF4G1,BSCL2,ELN,EML1,C8orf37,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,CDHR1,APC2,EYA1,REEP2,F8,ACSL4,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,NOP56,POMT1,STAMBP,TPK1,AP4B1,GABRA3,CHL1,GAD1,GALC,B4GALNT1,ERAP1,ATP8A2,INPP5K,TUBGCP4,GFAP,PPARGC1A,GJB1,GLDC,GLRB,GLUL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,GUCY1A1,AGBL5,CPT1C,IDH3B,RBPJ,TMEM240,IL12A,IBA57,TUBB2B,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,LIG4,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NF1,NTRK3,OCRL,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDYN,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,MBOAT7,FA2H,POLG,POLR2F,PPP2R2B,PRKCG,PRPH,CNNM2,NDUFS7,SAMD9,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RGR,RLBP1,RNASEL,SETD5,ROM1,ELP2,RPE65,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,PRCD,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,SLC1A3,PEX26,LIMS2,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,CDK5RAP2,SNCB,SNCA,UNC80,SOX2,SOX3,SPATA7,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,TTBK2,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,TACC1,SEMA4A,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,CSMD1,TNNT1,PIK3R5,AMACR,TSC1,TSC2,TTPA,TUB,TMEFF2,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,BEST1,CLIP2,WRN,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,DOCK8,GJC2,RNF170,SNX14,AAAS,GAN,JPH3" Human Phenotype HP:0002492 Abnormality of the corticospinal tract 5.64E-05 3.38E-01 1.17E-02 1.08E-01 297 1215 "ABAT,ADAR,KLRC4,ADCY5,ADD1,ADD3,SLC12A5,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,ALAD,KCNT1,AMPD2,AMT,CDC42BPA,ANK3,KCNAB2,ALS2,SLC7A14,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BBS2,BCS1L,FGF17,PROM1,SYNJ1,ST3GAL5,CACNA1G,NIPA1,CFAP410,CA4,CA8,CACNA1A,CACNA1D,CBS,AIFM1,AP4M1,LARGE1,CRLF1,ADGRG1,RAB33A,TPP1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,RUBCN,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,SLC12A6,ATN1,DSCAM,DTNA,DNM1L,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,AASS,EIF4G1,BSCL2,ELN,EML1,C8orf37,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,CDHR1,APC2,EYA1,REEP2,F8,ACSL4,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,NOP56,POMT1,STAMBP,TPK1,AP4B1,GABRA3,CHL1,GAD1,GALC,B4GALNT1,ERAP1,ATP8A2,INPP5K,TUBGCP4,GFAP,PPARGC1A,GJB1,GLDC,GLRB,GLUL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,GUCY1A1,AGBL5,CPT1C,IDH3B,RBPJ,TMEM240,IL12A,IBA57,TUBB2B,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,LIG4,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NF1,NTRK3,OCRL,OGDH,OPA1,OPHN1,PAH,TREM2,PAX6,PC,PDYN,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,MBOAT7,FA2H,POLG,POLR2F,PPP2R2B,PRKCG,PRPH,CNNM2,NDUFS7,SAMD9,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RGR,RLBP1,RNASEL,SETD5,ROM1,ELP2,RPE65,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,PRCD,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,SLC1A3,PEX26,LIMS2,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,CDK5RAP2,SNCB,SNCA,UNC80,SOX2,SOX3,SPATA7,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,TTBK2,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,TACC1,SEMA4A,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,CSMD1,TNNT1,PIK3R5,AMACR,TSC1,TSC2,TTPA,TUB,TMEFF2,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,BEST1,CLIP2,WRN,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,DOCK8,GJC2,RNF170,SNX14,AAAS,GAN,JPH3" Human Phenotype HP:0001337 Tremor 6.25E-05 3.75E-01 1.25E-02 1.16E-01 111 391 "ADAR,ADCY5,PCDH19,CC2D2A,PLA2G6,CEP126,CDC42BPA,ASPA,PTCH2,ATM,ATP2B3,FGF17,SYNJ1,SGCE,CACNA1G,NIPA1,CA8,CACNA1A,CACNA1B,AIFM1,RAB33A,TPP1,FBXO7,CP,TENM4,CX3CR1,KIAA0586,DNAJC6,DCTN1,RAB39B,DNM2,SLC12A6,EGFR,EIF4G1,BSCL2,ELN,TUBB4A,FGF14,FGFR1,GABRA1,GABRA3,GABRG2,GALC,ATP8A2,GCK,GFAP,GJB1,GRIK2,ADAMTS13,GRM1,HPCA,ATCAY,TMEM240,SLC6A17,TUBB2B,KCNA1,KCNA2,KCNC1,KCND3,KCNJ10,MAPT,MOBP,MYCN,MYO5A,NTRK3,OPA1,PAH,PAX6,PDYN,SNX10,PLP1,PMP22,POLG,PPP2R2B,CEP41,VPS13C,APTX,PEX2,QDPR,KCTD17,MYH14,FBXW7,LRRK2,ATXN2,ATXN7,SCN2A,SCP2,SLC30A10,SLC6A1,SLC20A2,SLCO1A2,SNCA,SOX10,ELOVL4,STXBP1,VPS13A,CNTN2,RPGRIP1L,ATP13A2,TNFRSF1B,TNNT1,PIK3R5,AMACR,TTPA,UBE3A,UCHL1,VLDLR,CLIP2,TMEM237,GJC2,JPH3" Human Phenotype HP:0001258 Spastic paraplegia 9.34E-05 5.61E-01 1.81E-02 1.68E-01 33 86 "KIDINS220,AMPD2,ALS2,KIF1A,NIPA1,CACNA1D,AP4M1,ATL1,BSCL2,REEP2,AP4B1,B4GALNT1,AP4S1,CPT1C,IBA57,KIF5A,L1CAM,ZFYVE27,PLP1,FA2H,POLG,SPART,STXBP1,VAMP1,DDHD2,ATP13A2,AP4E1,DDHD1,UCHL1,KLC2,REEP1,GJC2,GAN" Human Phenotype HP:0001257 Spasticity 1.01E-04 6.05E-01 1.83E-02 1.70E-01 218 863 "ADAR,ADCY5,ADD1,ADD3,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,KCNT1,AMPD2,AMT,ANK3,ALS2,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BCS1L,SYNJ1,CACNA1G,NIPA1,CFAP410,CACNA1A,CACNA1D,AP4M1,LARGE1,CRLF1,ADGRG1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,DSCAM,DTNA,EDN3,EDNRB,ATL1,SEMA3D,OPTN,AASS,EIF4G1,BSCL2,ELN,EML1,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,EYA1,REEP2,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,FOXG1,POMT1,STAMBP,TPK1,AP4B1,CHL1,GAD1,GALC,B4GALNT1,INPP5K,TUBGCP4,GFAP,PPARGC1A,GLDC,GLRB,PCLO,PARD3B,CIT,MFSD2A,AP4S1,CPT1C,RBPJ,TMEM240,IBA57,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NTRK3,OGDH,OPA1,OPHN1,PAH,TREM2,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,FA2H,POLG,POLR2F,PRPH,NDUFS7,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RNASEL,SETD5,ELP2,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,SNCB,SNCA,UNC80,SOX2,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,AHCYL2,ATP13A2,ZFPM2,AP4E1,DDHD1,CSMD1,TNNT1,AMACR,TTPA,TMEFF2,HEPACAM,UCHL1,FRRS1L,CLIP2,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,GJC2,SNX14,GAN,JPH3" Human Phenotype HP:0001276 Hypertonia 1.01E-04 6.05E-01 1.83E-02 1.70E-01 218 863 "ADAR,ADCY5,ADD1,ADD3,KIDINS220,HACE1,SORCS2,CC2D2A,PLA2G6,KCNT1,AMPD2,AMT,ANK3,ALS2,CASK,PDE8B,ASPA,ATM,ATP1A2,ATP1A3,KIF1A,BCS1L,SYNJ1,CACNA1G,NIPA1,CFAP410,CACNA1A,CACNA1D,AP4M1,LARGE1,CRLF1,ADGRG1,FBXO7,NIPBL,RTTN,CP,C2CD2,CSF1R,VAC14-AS1,PNPLA8,CTNND2,CX3CR1,RIPOR2,EARS2,MATR3,DBT,DNAJC6,DCTN1,SACS,ARNT2,RAB39B,DMPK,DSCAM,DTNA,EDN3,EDNRB,ATL1,SEMA3D,OPTN,AASS,EIF4G1,BSCL2,ELN,EML1,DCTN4,EMX2,EPB41,GPHN,ERBB4,ERCC2,EYA1,REEP2,TUBB3,TUBB4A,FKTN,FGFR1,FGFR3,FOXG1,POMT1,STAMBP,TPK1,AP4B1,CHL1,GAD1,GALC,B4GALNT1,INPP5K,TUBGCP4,GFAP,PPARGC1A,GLDC,GLRB,PCLO,PARD3B,CIT,MFSD2A,AP4S1,CPT1C,RBPJ,TMEM240,IBA57,KCNA1,KCND3,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,STXBP5,L1CAM,MAG,ZFYVE27,MAPT,MOBP,MSR1,MYO5A,NEXMIF,NDP,NEFH,NEK1,NTRK3,OGDH,OPA1,OPHN1,PAH,TREM2,NALCN,RETREG1,FTO,PLP1,PSAT1,PMS2,FA2H,POLG,POLR2F,PRPH,NDUFS7,VPS13C,PEX2,PEX5,QDPR,ROGDI,RET,PRRT2,RNASEL,SETD5,ELP2,LRRK2,RYR1,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,SLC30A10,FOXRED1,ARX,FUZ,NTNG1,NUBPL,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC8A3,SLC11A1,SLC20A2,SLCO1A2,SNCB,SNCA,UNC80,SOX2,SOX10,EMC1,SPTAN1,SPTB,SPART,ZC4H2,ELOVL4,STX1A,KANK1,STXBP1,KLHL7,MLC1,ABCC8,VAMP1,ARHGEF9,PLCB1,DDHD2,TAF6,RPGRIP1L,WASHC4,SLC19A3,AHCYL2,ATP13A2,ZFPM2,AP4E1,DDHD1,CSMD1,TNNT1,AMACR,TTPA,TMEFF2,HEPACAM,UCHL1,FRRS1L,CLIP2,KLC2,AGMO,REEP1,MFF,PRDM8,TUBA1A,GJC2,SNX14,GAN,JPH3" Human Phenotype HP:0002353 EEG abnormality 1.04E-04 6.25E-01 1.84E-02 1.71E-01 104 366 "DGCR6,ADD1,NLGN4X,HECW2,PCDH19,AMT,KCNAB2,AMER3,ASPA,ATP1A2,ALDH7A1,KIF1A,BCS1L,CACNA1A,CACNA2D1,CACNB4,LARGE1,NRXN3,NRXN1,RTTN,SH2B1,CX3CR1,DOCK4,KATNAL2,ZNF804A,DLG2,DMD,DNM1,SLC12A6,EEF1A2,AASS,EMX2,VPS13B,ERCC2,APC2,FKTN,FGF12,FOXG1,POMT1,GAA,GABRA1,GABRB1,GABRB3,GABRG2,GALC,GCK,GFAP,GLDC,GNAO1,GRIN2D,HTR2A,RBPJ,DOCK7,KCNB1,KCNJ11,KCNMA1,KCNQ2,KCNQ3,MAPT,NEXMIF,NDP,NF1,OCRL,PAH,TREM2,PAX6,NLGN3,RELN,PIGG,PEX2,PEX5,ROGDI,PRRT2,TMLHE,SCN2A,SCN8A,ARX,NTNG1,ST3GAL3,SLC1A2,PEX26,SLC6A1,MBD5,SPTAN1,IQSEC2,NPAS3,STXBP1,ABCC8,PLCB1,SYN2,CNTN2,SZT2,NSD1,CSMD1,TSC1,TSC2,TUBB2A,UBE3A,VIPR2,NSD2,ZIC1,MFF,NLRP3,AP3B2" Human Phenotype HP:0002411 Myokymia 1.15E-04 6.91E-01 1.98E-02 1.83E-01 18 37 "ADCY5,CACNA1G,PNKD,C2CD2,RIPOR2,DSCAM,PARD3B,KCNA1,KCNQ2,STXBP5,PPP2R2B,PRKCG,PRRT2,SLC11A1,AHCYL2,ZFPM2,UCHL1,AGMO" Human Phenotype HP:0010993 Abnormality of the cerebral subcortex 1.28E-04 7.70E-01 2.14E-02 1.99E-01 167 639 "ABAT,RBM10,ARID1A,ADD1,KIDINS220,HACE1,WDR35,CC2D2A,KCNT1,AMPD2,AMT,KCNAB2,APC,CDK13,PDE8B,KIF1A,SYNJ1,ISPD,AIFM1,AP4M1,LARGE1,RAB33A,NIPBL,RTTN,CSF1R,EARS2,KIAA0586,DCC,ZEB2,KIAA0753,ARNT2,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,EDN3,EDNRB,ATL1,SEMA3D,BSCL2,EML1,EMX2,VPS13B,ERCC2,APC2,WAC,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,TMEM107,STAMBP,AP4B1,GABRB1,GABRB3,GALC,ATP8A2,AHDC1,GFAP,GJB1,GLDC,GLI2,GLUL,GNAO1,GNAS,GPT2,PCLO,CIT,MFSD2A,RBPJ,DOCK7,IBA57,TUBB2B,KCNQ2,KIF2A,KIF5C,L1CAM,LAMA2,LIG4,MAG,MAPT,MEF2C,MID1,NEXMIF,NDP,NEK1,NF1,NFIA,NFIX,OCRL,PAH,TREM2,PAX6,PC,PDYN,GPSM2,PLP1,PSAT1,PMS2,PRRX1,FA2H,POLG,KANSL1,CEP41,LAMA1,PIGG,PTCH1,TMEM260,PEX2,PEX5,TMEM231,FAT4,RET,KIF7,LRRK2,SALL1,ATXN2,SCN4B,ARX,FUZ,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC20A2,SMARCA4,CDK5RAP2,SMARCE1,SNCA,UNC80,SON,SOX2,SOX3,SOX11,EMC1,ZNF423,SPTAN1,POGZ,STXBP1,MLC1,VPS13A,DDHD2,TCF4,RPGRIP1L,SZT2,SLC19A3,NSD1,ZFPM2,TK2,KAT6B,TSC1,TSC2,TUBB2A,HEPACAM,NSD2,PORCN,ZIC1,TMEM237,POLR3H,TUBA1A,GJC2,AP3B2" Human Phenotype HP:0001310 Dysmetria 1.44E-04 8.65E-01 2.34E-02 2.17E-01 40 113 "PLA2G6,PTCH2,ATP1A3,KIF1A,CA8,PNPLA8,SACS,ELN,FGFR1,B4GALNT1,ATP8A2,GJB1,GRM1,TUBB2B,MAG,MYCN,OPA1,OPHN1,PDYN,PLP1,FA2H,PPP2R2B,PRKCG,PEX2,FBXW7,ATXN1,ATXN2,ATXN7,SCN8A,SLC20A2,SPART,CAMTA1,SYNE1,PIK3R5,TTPA,UCHL1,VLDLR,CLIP2,XRCC4,GJC2" Human Phenotype HP:0011146 Dialeptic seizures 1.82E-04 1.00E+00 2.83E-02 2.63E-01 28 71 "SLC12A5,PCDH19,CACNA1D,CACNB4,LGI1,PNPLA8,DNM1,GABRA1,GABRB3,GABRG2,KCNMA1,KCNQ2,KCNQ3,LAMA2,RELN,LAMA1,PRRT2,STX1B,SCN2A,SLC6A1,IQSEC2,STXBP1,SZT2,TSC1,TSC2,UBE3A,FMN2,EPM2A" Human Phenotype HP:0011153 Focal motor seizures 1.84E-04 1.00E+00 2.83E-02 2.63E-01 16 32 "SLC12A5,PCDH19,AMT,CACNA1D,CACNB4,LGI1,GABRA1,GABRB3,GABRG2,GLDC,KCNQ2,KCNQ3,RELN,SCN2A,STXBP1,EPM2A" Human Phenotype HP:0007334 Generalized tonic-clonic seizures with focal onset 1.95E-04 1.00E+00 2.92E-02 2.71E-01 11 18 "SLC12A5,PCDH19,LGI1,GABRA1,GABRG2,KCNQ2,KCNQ3,RELN,SCN2A,STXBP1,EPM2A" Human Phenotype HP:0003781 Excessive salivation 2.02E-04 1.00E+00 2.95E-02 2.74E-01 33 89 "SLC12A5,ALS2,ATP1A3,CFAP410,AP4M1,NRXN1,VAC14-AS1,MATR3,ZEB2,OPTN,ERBB4,FOXG1,GABRG2,PPARGC1A,GPT2,TUBB2B,KCNQ2,NEFH,NEK1,PAH,TREM2,PAK3,PRPH,QDPR,REV3L,SETD5,ATXN2,SPART,ZC4H2,VPS13A,NSD1,AP4E1,UBE3A" Human Phenotype HP:0002363 Abnormality of brainstem morphology 2.55E-04 1.00E+00 3.50E-02 3.25E-01 57 181 "CC2D2A,KIF1A,CFAP410,CA8,ISPD,KRIT1,LARGE1,ADGRG1,CTNND2,MATR3,DNM1,DTNA,DNAJB6,OPTN,ERBB4,TUBB3,FKTN,FGFR3,POMT1,GABRB3,ATP8A2,TUBA8,GFAP,PPARGC1A,PCLO,CIT,GSN,MFSD2A,DOCK7,TUBB2B,ITGA7,LAMA2,MYH3,MYH7,NEFH,NEK1,TREM2,NALCN,FA2H,PRPH,LAMA1,TMEM231,REV3L,RYR1,ATXN1,ATXN2,SCN4B,FUZ,ZNF423,SPTAN1,RPGRIP1L,TPM2,TPM3,TUBB2A,VLDLR,TMEM237,TUBA1A" Human Phenotype HP:0001274 Agenesis of corpus callosum 2.58E-04 1.00E+00 3.50E-02 3.25E-01 70 233 "ABAT,ARID1A,KIDINS220,WDR35,AMT,KCNAB2,APC,CDK13,ISPD,LARGE1,NIPBL,DCC,ZEB2,KIAA0753,ARNT2,MED12,CDON,SLC12A6,EDN3,EDNRB,SEMA3D,EML1,ERCC2,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,GFAP,GLDC,GLI2,CIT,MFSD2A,TUBB2B,L1CAM,MID1,NEK1,NFIA,NFIX,PDYN,GPSM2,PSAT1,PMS2,PRRX1,CEP41,PTCH1,TMEM260,RET,KIF7,SALL1,SCN4B,ARX,FUZ,RAB3GAP1,SMARCA4,CDK5RAP2,SMARCE1,SOX2,SOX3,SOX11,RPGRIP1L,NSD1,ZFPM2,KAT6B,NSD2,PORCN,ZIC1,TMEM237,TUBA1A" Human Phenotype HP:0001260 Dysarthria 2.59E-04 1.00E+00 3.50E-02 3.25E-01 123 455 "KLRC4,ADCY5,PLA2G6,BIN1,ALS2,PDE8B,ATM,ATP1A2,ATP1A3,ATP2B3,BCS1L,FGF17,SYNJ1,CACNA1G,CFAP410,CA8,CACNA1A,CACNB4,TPP1,FBXO7,RTTN,CP,PNKD,PNPLA8,RUBCN,MATR3,DNAJC6,DCTN1,SACS,RAB39B,OPTN,ELN,ERBB4,ERCC2,TUBB4A,FGF14,FGFR1,FGFR3,NOP56,AP4B1,B4GALNT1,ERAP1,ATP8A2,INPP5K,GFAP,PPARGC1A,GJB1,GPT2,GRM1,ELOVL5,HPCA,ATCAY,TMEM240,IL12A,TUBB2B,JAK2,KCNA1,KCND3,MAG,MAPT,MOBP,NEFH,NEK1,TREM2,PDYN,SERPINI1,A2ML1,PLP1,PMS2,FA2H,POLG,PPP2R2B,PRKCG,PRPH,NDUFS7,APTX,PEX2,REV3L,PRRT2,KCTD17,LRRK2,ATXN1,ATXN2,ATXN7,SCN8A,SLC30A10,FOXRED1,ARX,SLC1A3,SLC6A1,SLC20A2,SLCO1A2,SNAP25,SNCA,DOP1A,SOX10,SPART,ELOVL4,TTBK2,VAMP1,VPS13A,DDHD2,CAMTA1,DMXL2,SYNE1,SLC19A3,ATP13A2,TK2,TLR4,KAT6B,PIK3R5,TTPA,HEPACAM,VLDLR,CLIP2,KLC2,XRCC4,REEP1,PRDM8,GJC2,AAAS,GAN,JPH3" Human Phenotype HP:0007364 Aplasia/Hypoplasia of the cerebrum 2.65E-04 1.00E+00 3.50E-02 3.25E-01 291 1210 "ABAT,ARID1A,ADAR,ADD1,ADD3,SLC12A5,KIDINS220,HECW2,PCDH19,AGT,HACE1,WDR35,CC2D2A,PLA2G6,ALK,KCNT1,AMPD2,AMT,ANK1,KCNAB2,APC,ALS2,CASK,ARSE,CDK13,ASPA,ATM,ALDH7A1,KIF1A,BCS1L,BLM,SYNJ1,ST3GAL5,CACNA1B,ISPD,AIFM1,AP4M1,CDC42,LARGE1,CHN1,COG1,TPP1,NIPBL,WHRN,RTTN,SEC24C,CTNND2,HDAC4,EARS2,KIAA0586,DCC,DNAJC6,ZEB2,KIAA0753,ARNT2,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,DPP6,DSCAM,DYRK1A,DNM1L,USH1C,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,BSCL2,ELN,EML1,EMX2,VPS13B,ERCC2,APC2,ADGRV1,EYA1,WAC,ACSL4,TUBB3,TUBB4A,FKTN,GORAB,FGF12,FGFR1,FGFR3,MAD2L2,FOXG1,POMT1,TMEM107,APOPT1,STAMBP,DLL3,AP4B1,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,ATP8A2,INPP5K,TUBGCP4,TUBA8,SRCAP,AHDC1,GFAP,MMADHC,FREM1,GLDC,GLI2,GLUL,GNAO1,GPT2,GP1BB,PCLO,GRIN2D,CIT,MFSD2A,AP4S1,HBA1,HNMT,IGF1,RBPJ,DOCK7,IBA57,RIPPLY2,TUBB2B,KCNJ5,KCNJ11,KCNQ2,KIF2A,KIF5A,KIF5C,KIT,L1CAM,LIG4,LMO1,MAG,NAT8L,MAPT,MEF2C,MEIS2,MID1,MOBP,MTR,MYCN,MYH3,MYO5A,MYO7A,NEXMIF,NDP,NEK1,NF1,NFIA,NFIX,NTRK3,CHAMP1,OPHN1,PAH,TREM2,PAK3,PAX6,PDYN,SERPINI1,NALCN,GPSM2,FTO,PLP1,PSAT1,PMS2,PRRX1,MBOAT7,FA2H,POLG,PPP2R2B,KANSL1,CEP41,PRKAR1B,MASP1,RELN,CNNM2,VPS13C,PIGG,PTCH1,TMEM260,PEX2,PEX5,TMEM231,QDPR,FAT4,ROGDI,RBBP8,RET,PRRT2,KIF7,SETD5,ALG9,SALL1,SBF1,SCN2A,SCN4B,SCN8A,PUF60,ARX,FUZ,NTNG1,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC20A2,SLCO1A2,SMARCA4,DMRTC1,CDK5RAP2,SMARCE1,MBD5,SNRPN,UNC80,SON,SOX2,SOX3,ZCCHC24,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,POGZ,SMOC1,ZC4H2,ELOVL4,KANK1,STXBP1,ABCC8,VPS13A,DDHD2,CAMTA1,TAF6,ALG1,TBX15,TCF4,SATB2,RPGRIP1L,NSD1,ATP13A2,ZFPM2,AP4E1,TK2,ERCC6L2,PARD3,KAT6B,TRIO,TRPS1,TSC1,TSC2,TUBB2A,HIRA,HEPACAM,UBE3A,UCHL1,FRRS1L,CLIP2,NSD2,PORCN,XRCC4,ZIC1,ZIC2,ZBTB16,TMEM237,POLR3H,MFF,TUBA1A,PCDH15,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,VANGL2,SNX14,AAAS,AP3B2,LAS1L" Human Phenotype HP:0002307 Drooling 2.69E-04 1.00E+00 3.50E-02 3.25E-01 31 83 "ALS2,ATP1A3,CFAP410,AP4M1,NRXN1,VAC14-AS1,MATR3,ZEB2,OPTN,ERBB4,FOXG1,GABRG2,PPARGC1A,GPT2,TUBB2B,KCNQ2,NEFH,NEK1,PAH,TREM2,PAK3,PRPH,REV3L,SETD5,ATXN2,SPART,ZC4H2,VPS13A,NSD1,AP4E1,UBE3A" Human Phenotype HP:0002266 Focal clonic seizures 2.77E-04 1.00E+00 3.53E-02 3.28E-01 8 11 "SLC12A5,PCDH19,GABRA1,GABRG2,KCNQ2,KCNQ3,SCN2A,STXBP1" Human Phenotype HP:0100547 Abnormality of forebrain morphology 2.87E-04 1.00E+00 3.59E-02 3.33E-01 356 1515 "ABAT,ACADM,RBM10,ARID1A,ADAR,ADD1,ADD3,SLC12A5,KIDINS220,HECW2,PCDH19,AGT,HACE1,WDR35,CC2D2A,PLA2G6,ALK,KCNT1,AMPD2,AMT,ANK1,KCNAB2,APC,ALS2,APP,CASK,ARSE,CDK13,PDE8B,ASPA,PTCH2,ATM,ALDH7A1,KIF1A,MPDZ,BCS1L,FGF17,BLM,SYNJ1,ST3GAL5,CFAP410,CA8,CACNA1B,ISPD,KRIT1,AIFM1,AP4M1,CDC42,LARGE1,ADGRG1,CHN1,RAB33A,COG1,TPP1,NIPBL,WHRN,RTTN,CPS1,C2CD2,CSF1R,SEC24C,CNTNAP2,CTNND2,CX3CR1,RIPOR2,HDAC4,EARS2,MATR3,KIAA0586,DBT,DCC,DNAJC6,ZEB2,KIAA0753,ARNT2,RAB39B,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,DPP6,DSCAM,DYRK1A,DNM1L,USH1C,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,OPTN,EGFR,EIF4G1,BSCL2,ELN,EML1,EMX2,VPS13B,GPHN,ERBB2,ERBB4,ERCC2,APC2,ADGRV1,EYA1,WAC,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,POMT1,TMEM107,APOPT1,STAMBP,DLL3,AP4B1,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,ATP8A2,INPP5K,TUBGCP4,TUBA8,SRCAP,AHDC1,GFAP,MMADHC,FREM1,PPARGC1A,GJB1,GLDC,GLI2,GLUL,GNAO1,GNAS,GPT2,GP1BB,PCLO,PARD3B,GRIN2D,CIT,MFSD2A,AP4S1,HBA1,HNMT,IGF1,RBPJ,DOCK7,IBA57,RIPPLY2,TUBB2B,KCNJ5,KCNJ11,KCNQ2,KIF2A,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LIG4,LMO1,MAG,NAT8L,MAPT,MEF2C,MEIS2,MID1,MOBP,MTR,MYCN,MYH3,MYO5A,MYO7A,NEXMIF,NDP,NEFH,NEK1,NF1,NFIA,NFIX,NTRK3,DDR2,OCRL,CHAMP1,OPHN1,PAH,TREM2,PAK3,PAX6,PC,PDYN,SERPINI1,NALCN,PKD1,GPSM2,FTO,PLP1,PSAT1,PMS2,PRRX1,MBOAT7,FA2H,POLG,PPP2R2B,KANSL1,CEP41,PRKAR1B,PRPH,MASP1,RELN,CNNM2,NDUFS7,VPS13C,LAMA1,PIGG,PTCH1,TMEM260,PEX2,PEX5,TMEM231,QDPR,FAT4,ROGDI,RBBP8,RET,PRRT2,KIF7,SETD5,ALG9,LRRK2,SALL1,SBF1,ATXN2,SCN2A,SCN4B,SCN8A,SCP2,FOXRED1,PUF60,ARX,FUZ,NTNG1,ST3GAL3,NUBPL,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC11A1,SLC20A2,SLCO1A2,SMARCA4,DMRTC1,CDK5RAP2,SMARCE1,SNCB,SNCA,MBD5,SNRPN,UNC80,SON,SOX2,SOX3,ZCCHC24,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,POGZ,STOX1,SMOC1,ZC4H2,ELOVL4,KANK1,STXBP1,MLC1,ABCC8,VPS13A,TACC1,DDHD2,CAMTA1,TAF6,ALG1,TBX15,TCF4,SATB2,RPGRIP1L,SZT2,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,AP4E1,GPR161,TK2,ERCC6L2,PARD3,KAT6B,TRH,TRIO,TRPS1,TSC1,TSC2,TUBB2A,HIRA,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,CLIP2,NSD2,PORCN,XRCC4,ZIC1,ZIC2,AGMO,ZBTB16,TMEM237,POLR3H,MFF,PRDM8,TUBA1A,PCDH15,EPM2A,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,VANGL2,SNX14,AAAS,AP3B2,LAS1L" Human Phenotype HP:0011338 Abnormality of mouth shape 2.97E-04 1.00E+00 3.59E-02 3.33E-01 56 178 "KIF1A,DST,NIPBL,CTNND2,HDAC4,ZEB2,MED12,TRAPPC9,EEF1A2,ELN,VPS13B,WAC,STRADA,FGFR1,CHL1,GCK,SRCAP,GK,PCLO,IL1RAPL1,HNRNPK,KCNH1,KCNJ11,LAMA2,LIFR,MEF2C,MYH3,OCRL,CHAMP1,PAK3,PDE4D,NALCN,PIK3R1,MAGEL2,KANSL1,MASP1,LAMA1,FAT4,REV3L,KIF7,SETD5,SLC6A8,DMRTC1,MBD5,SNRPN,UNC80,SOX5,SOX11,POGZ,ABCC8,TAF6,TCF4,CLIP2,NSD2,TMEM237,KAT6A" Human Phenotype HP:0002060 Abnormality of the cerebrum 3.00E-04 1.00E+00 3.59E-02 3.33E-01 355 1511 "ABAT,ACADM,RBM10,ARID1A,ADAR,ADD1,ADD3,SLC12A5,KIDINS220,HECW2,PCDH19,AGT,HACE1,WDR35,CC2D2A,PLA2G6,ALK,KCNT1,AMPD2,AMT,ANK1,KCNAB2,APC,ALS2,APP,CASK,ARSE,CDK13,PDE8B,ASPA,PTCH2,ATM,ALDH7A1,KIF1A,MPDZ,BCS1L,FGF17,BLM,SYNJ1,ST3GAL5,CFAP410,CA8,CACNA1B,ISPD,KRIT1,AIFM1,AP4M1,CDC42,LARGE1,ADGRG1,CHN1,RAB33A,COG1,TPP1,NIPBL,WHRN,RTTN,CPS1,C2CD2,CSF1R,SEC24C,CNTNAP2,CTNND2,CX3CR1,RIPOR2,HDAC4,EARS2,MATR3,KIAA0586,DBT,DCC,DNAJC6,ZEB2,KIAA0753,ARNT2,RAB39B,DNM1,DMPK,MED12,TRAPPC9,CDON,SLC12A6,DPP6,DSCAM,DYRK1A,DNM1L,USH1C,EDN3,EDNRB,ATL1,EEF1A2,SEMA3D,OPTN,EGFR,EIF4G1,BSCL2,ELN,EML1,EMX2,VPS13B,GPHN,ERBB2,ERBB4,ERCC2,APC2,ADGRV1,EYA1,WAC,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,POMT1,TMEM107,APOPT1,STAMBP,DLL3,AP4B1,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,ATP8A2,INPP5K,TUBGCP4,TUBA8,SRCAP,AHDC1,GFAP,MMADHC,FREM1,PPARGC1A,GJB1,GLDC,GLI2,GLUL,GNAO1,GNAS,GPT2,GP1BB,PCLO,PARD3B,GRIN2D,CIT,MFSD2A,AP4S1,HBA1,HNMT,IGF1,RBPJ,DOCK7,IBA57,RIPPLY2,TUBB2B,KCNJ5,KCNJ11,KCNQ2,KIF2A,KIF5A,KIF5C,KIT,STXBP5,L1CAM,LAMA2,LIG4,LMO1,MAG,NAT8L,MAPT,MEF2C,MEIS2,MID1,MOBP,MTR,MYCN,MYH3,MYO5A,MYO7A,NEXMIF,NDP,NEFH,NEK1,NF1,NFIA,NFIX,NTRK3,DDR2,OCRL,CHAMP1,OPHN1,PAH,TREM2,PAK3,PAX6,PC,PDYN,SERPINI1,NALCN,PKD1,GPSM2,FTO,PLP1,PSAT1,PMS2,PRRX1,MBOAT7,FA2H,POLG,PPP2R2B,KANSL1,CEP41,PRKAR1B,PRPH,MASP1,RELN,CNNM2,NDUFS7,VPS13C,LAMA1,PIGG,PTCH1,TMEM260,PEX2,PEX5,TMEM231,QDPR,FAT4,ROGDI,RBBP8,RET,PRRT2,KIF7,SETD5,ALG9,LRRK2,SALL1,SBF1,ATXN2,SCN2A,SCN4B,SCN8A,SCP2,FOXRED1,PUF60,ARX,FUZ,NTNG1,ST3GAL3,NUBPL,SLC1A2,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC11A1,SLC20A2,SLCO1A2,SMARCA4,DMRTC1,CDK5RAP2,SMARCE1,SNCB,SNCA,MBD5,SNRPN,UNC80,SON,SOX2,SOX3,ZCCHC24,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,POGZ,STOX1,SMOC1,ZC4H2,ELOVL4,KANK1,STXBP1,MLC1,ABCC8,VPS13A,TACC1,DDHD2,CAMTA1,TAF6,ALG1,TBX15,TCF4,SATB2,RPGRIP1L,SZT2,SLC19A3,NSD1,AHCYL2,ATP13A2,ZFPM2,AP4E1,GPR161,TK2,ERCC6L2,PARD3,KAT6B,TRIO,TRPS1,TSC1,TSC2,TUBB2A,HIRA,HEPACAM,UBE3A,UCHL1,FRRS1L,VLDLR,CLIP2,NSD2,PORCN,XRCC4,ZIC1,ZIC2,AGMO,ZBTB16,TMEM237,POLR3H,MFF,PRDM8,TUBA1A,PCDH15,EPM2A,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,VANGL2,SNX14,AAAS,AP3B2,LAS1L" Human Phenotype HP:0001761 Pes cavus 3.05E-04 1.00E+00 3.59E-02 3.33E-01 60 194 "PLEKHG5,BIN1,CDC42BPA,KCNAB2,ALS2,PRX,ATP1A3,FGF17,SYNJ1,NIPA1,AIFM1,RAB33A,DCAF8,DNAJC6,SACS,DNM2,ATL1,BSCL2,REEP2,FGF14,FGFR1,B4GALNT1,GJB1,KIF5A,L1CAM,LAMP2,MYH7,NEFH,NF1,PLP1,PMP22,POLG,POLR2F,APTX,PEX2,PEX5,SH3TC2,RET,SLC6A8,SOX10,KIF1B,IQSEC2,SPART,FGD4,VAMP1,VPS13A,TRIM2,ATP13A2,DDHD1,PIK3R5,TPM3,TTPA,UCHL1,KLC2,XRCC4,REEP1,GJC2,NLRP3,GAN,LAS1L" Human Phenotype HP:0025270 Abnormality of esophagus physiology 3.14E-04 1.00E+00 3.62E-02 3.36E-01 154 592 "ADAR,KLRC4,ADCY6,ADD3,PLA2G6,LTBP4,AMT,CNTNAP1,KCNAB2,ALS2,APP,ASCL1,PDE8B,ASPA,ATP1A3,KIF1A,CACNA1G,CFAP410,CACNA1A,NRXN1,NIPBL,COL4A5,PNKD,C2CD2,SH2B1,CRMP1,SEC24C,VAC14-AS1,CTNND2,CX3CR1,CYBB,RIPOR2,KIAA0513,MATR3,DCTN1,ARNT2,DNM1,DMPK,DSCAM,DNAJB6,EDN1,EDN3,EDNRB,SEMA3D,OPTN,FAM13A,ELN,DCTN4,ERBB4,TUBB4A,FGFR3,FOXG1,APOPT1,MEGF10,GAA,GABRB3,ERAP1,GFAP,PPARGC1A,GJB1,GLDC,GP1BB,PARD3B,GRIN2D,GUCY1A1,HPCA,IL12A,ITGA7,KCND3,KCNQ2,KIF5A,KIT,STXBP5,LAMA2,LIFR,LIG4,MAPT,MEIS2,MID1,MOBP,MSR1,MYH7,NEXMIF,NCF2,NEFH,NEK1,NF1,NOS1,NTRK3,OCRL,CHAMP1,TREM2,PDGFRA,NALCN,RETREG1,PLEC,PLP1,POLG,PRKCG,PRPH,SAMD9,LAMA1,QDPR,RET,REV3L,PRRT2,SETD5,LRRK2,RYR1,SALL1,ATXN1,ATXN2,ATXN7,SCN4B,ARX,FERMT1,FUZ,NTNG1,SLC6A9,SLC8A3,SLC11A1,SLCO1A2,DMRTC1,SNCA,SOX5,POGZ,SS18,TTBK2,STX1A,VAMP1,VPS13A,ATP11A,DDHD2,TAF6,TCF4,SLC19A3,AHCYL2,ZFPM2,TK2,TLR4,KAT6B,PIK3R5,TPM2,TPM3,HIRA,CLIP2,NSD2,PORCN,AGMO,REEP1,WNK1,MFF,JMJD1C,AAAS" Human Phenotype HP:0002072 Chorea 3.46E-04 1.00E+00 3.91E-02 3.63E-01 55 175 "ADAR,ADCY5,SLITRK1,ADD1,PLA2G6,AMT,ATM,ATP1A2,ATP1A3,ST3GAL5,CFAP410,CP,PNKD,MATR3,ATN1,OPTN,ERBB4,ERCC2,TUBB4A,FOXG1,GFAP,PPARGC1A,GLDC,GNAO1,GNAS,JAK1,JAK2,KCNQ2,KCNQ3,KIF5A,MTTP,NEFH,NEK1,GPR88,TREM2,PLP1,POLG,PRPH,APTX,QDPR,PRRT2,ELP2,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,ARX,SLC6A8,SLC20A2,VPS13A,PIK3R5,FRRS1L,GJC2,JPH3" Human Phenotype HP:0001347 Hyperreflexia 3.60E-04 1.00E+00 4.00E-02 3.71E-01 155 598 "ABAT,KLRC4,ADCY5,ADD1,KIDINS220,CC2D2A,PLA2G6,KCNT1,AMPD2,AMT,CDC42BPA,ALS2,SLC7A14,CASK,PDE8B,KIF1A,BBS2,BCS1L,PROM1,ST3GAL5,CACNA1G,NIPA1,CA4,CA8,CACNA1A,AP4M1,LARGE1,ADGRG1,TPP1,FBXO7,C2CD2,CSF1R,VAC14-AS1,RUBCN,RIPOR2,MATR3,DCTN1,SACS,DSCAM,ATL1,BSCL2,ELN,C8orf37,GPHN,CDHR1,APC2,EYA1,REEP2,ACSL4,MAD2L2,NOP56,AP4B1,GAD1,GALC,B4GALNT1,ERAP1,ATP8A2,GFAP,GJB1,GLDC,GLUL,GPT2,PCLO,PARD3B,GRM1,CIT,MFSD2A,AP4S1,AGBL5,CPT1C,IDH3B,IL12A,TUBB2B,KCNA1,KCND3,KCNQ2,KIF5A,STXBP5,L1CAM,ZFYVE27,MAPT,NDP,NEFH,OCRL,OPA1,PAH,TREM2,PC,PDYN,NALCN,PLP1,MBOAT7,FA2H,POLG,PPP2R2B,PRKCG,PRPH,CNNM2,NDUFS7,VPS13C,PEX2,PEX5,PRRT2,RGR,RLBP1,ROM1,ELP2,RPE65,ATXN1,ATXN7,PRCD,FOXRED1,ARX,NUBPL,PEX26,RAB3GAP1,SLC11A1,SLC20A2,CDK5RAP2,SNCA,SPATA7,SPTAN1,SPART,TTBK2,KLHL7,ABCC8,VAMP1,PLCB1,SEMA4A,DDHD2,RPGRIP1L,NSD1,AHCYL2,ATP13A2,ZFPM2,CRB1,AP4E1,DDHD1,TLR4,TUB,UBE3A,UCHL1,VLDLR,BEST1,CLIP2,WRN,KLC2,AGMO,REEP1,MFF,PRDM8,GJC2,AAAS,GAN,JPH3" Human Phenotype HP:0010550 Paraplegia 3.74E-04 1.00E+00 4.08E-02 3.79E-01 49 152 "KIDINS220,AMPD2,ALS2,KIF1A,FGF17,NIPA1,CACNA1D,AP4M1,C2CD2,RIPOR2,DSCAM,ATL1,BSCL2,REEP2,FGFR1,FGFR3,AP4B1,B4GALNT1,PARD3B,AP4S1,CPT1C,IBA57,KIF5A,STXBP5,L1CAM,LIG4,ZFYVE27,PAH,PLP1,FA2H,POLG,SAMD9,SLC11A1,SOX10,SPART,STXBP1,VAMP1,DDHD2,AHCYL2,ATP13A2,ZFPM2,AP4E1,DDHD1,UCHL1,KLC2,AGMO,REEP1,GJC2,GAN" Human Phenotype HP:0006989 Dysplastic corpus callosum 3.83E-04 1.00E+00 4.11E-02 3.81E-01 72 244 "ABAT,ARID1A,KIDINS220,WDR35,AMT,KCNAB2,APC,CDK13,ISPD,LARGE1,NIPBL,EARS2,KIAA0586,DCC,ZEB2,KIAA0753,ARNT2,MED12,CDON,SLC12A6,EDN3,EDNRB,SEMA3D,EML1,ERCC2,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,GFAP,GLDC,GLI2,CIT,MFSD2A,TUBB2B,L1CAM,MID1,NEK1,NFIA,NFIX,PDYN,GPSM2,PSAT1,PMS2,PRRX1,CEP41,PTCH1,TMEM260,RET,KIF7,SALL1,SCN4B,ARX,FUZ,RAB3GAP1,SMARCA4,CDK5RAP2,SMARCE1,SOX2,SOX3,SOX11,RPGRIP1L,NSD1,ZFPM2,KAT6B,NSD2,PORCN,ZIC1,TMEM237,TUBA1A" Human Phenotype HP:0001252 Muscular hypotonia 4.09E-04 1.00E+00 4.31E-02 3.99E-01 299 1254 "ABAT,DGCR6,ACADM,RBM10,ARID1A,ADCY5,ADCY6,PTCHD1,KIDINS220,HECW2,PCDH19,HACE1,CC2D2A,PLA2G6,ALAD,LTBP4,KCNT1,AMPD2,BIN1,AMT,CDC42BPA,ANK3,CNTNAP1,KCNAB2,PRX,CASK,CDK13,ASCL1,ASPA,ATP1A3,ATP2B3,ALDH7A1,KIF1A,BCS1L,FGF17,DST,SYNJ1,ST3GAL5,SGCE,CA8,CACNA1A,ISPD,AIFM1,AP4M1,LARGE1,CFL2,RAB33A,CLCN4,NRXN1,COG1,NIPBL,CNTN1,COL11A2,CPS1,PREPL,SH2B1,SEC24C,PNPLA8,CTNND2,HDAC4,EARS2,KIAA0586,DBT,ZEB2,B3GAT3,KIAA0753,DLG3,DMD,DNM1,DMPK,MED12,TRAPPC9,DNM2,SLC12A6,DSCAM,GNE,DYRK1A,DNM1L,EDN3,EDNRB,EEF1A2,AASS,ELN,VPS13B,COQ7,GPHN,ERCC2,APC2,WAC,ACSL4,TUBB3,TUBB4A,FKTN,STRADA,GORAB,FGF12,FGFR1,FGFR3,MAD2L2,FOXG1,POMT1,APOPT1,STAMBP,TPK1,AP4B1,MEGF10,GAA,GABRA1,CHL1,GABRB1,GABRB3,GABRG2,GALC,ATP8A2,INPP5K,GCK,TUBA8,AHDC1,GFAP,MMADHC,GJB1,GLDC,GLI2,GLUL,GPT2,GP1BB,PCLO,GRIN2D,GRM1,PRDM5,MFSD2A,AP4S1,HBA1,HNRNPK,ZDHHC15,ATCAY,GAREM2,RBPJ,IBA57,TUBB2B,ITGA7,KCNB1,KCNH1,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF5A,KIT,LAMA2,LIFR,LIG4,MAG,NAT8L,MEF2C,MITF,MTTP,MTR,MYH7,MYO5A,NEXMIF,NDP,NF1,NFIA,NFIX,NTRK3,DDR2,OCRL,CHAMP1,OGDH,OPA1,OPHN1,PAX6,PC,PDE4D,NALCN,A2ML1,RETREG1,PLP1,PMP22,PMS2,MAGEL2,MBOAT7,POLG,POLR2F,PPM1B,KANSL1,CEP41,NDUFS7,LAMA1,WDR25,PIGG,PTCH1,BDNF-AS,PEX2,PEX5,TMEM231,QDPR,FAT4,RET,REV3L,PRRT2,KCTD17,KIF7,SETD5,ALG9,ELP2,RPE65,MEG3,RYR1,ATXN1,ATXN2,SCN2A,SCN4B,SCN8A,FOXRED1,ARX,FUZ,ST3GAL3,NUBPL,SLC1A2,SLC1A3,PEX26,SLC6A8,RAB3GAP1,SMARCA4,DMRTC1,SMARCE1,MBD5,LMBRD1,SNRPN,UNC80,DOP1A,SON,SOX2,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,SPTAN1,IQSEC2,POGZ,ZC4H2,KANK1,STXBP1,ABCC8,VPS13A,PLCB1,CAMTA1,TAF6,ALG1,TCF4,SATB2,TRIM2,RPGRIP1L,SZT2,SLC19A3,NSD1,ZFPM2,CRB1,AP4E1,THRA,TK2,ERCC6L2,KAT6B,TPM2,TPM3,TRPS1,KCNE5,TUBB2A,HIRA,HEPACAM,UBE3A,FRRS1L,DNAJC12,VLDLR,CLIP2,NSD2,LGI4,ZIC1,FMN2,TMEM237,POLR3H,WNK1,MFF,TUBA1A,PDSS2,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,SNX14,AAAS,AP3B2,GAN,LAS1L" Human Phenotype HP:0000759 Abnormal peripheral nervous system morphology 4.45E-04 1.00E+00 4.60E-02 4.27E-01 300 1260 "PLEKHG5,KLRC4,ADCY6,GRAMD1B,HACE1,PLA2G6,ALAD,CEP126,LTBP4,ALK,AMPD2,AMPD3,BIN1,AMT,ANK1,CNTNAP1,KCNAB2,APC,ALS2,APP,SLC7A14,PRX,ARSE,ASCL1,ASPA,PTCH2,ATM,ATP1A3,STX16,KIF1A,BBS2,FGF17,PROM1,DST,SYNJ1,ST3GAL5,MTMR2,CACNA1G,NIPA1,CFAP410,CA4,CACNA1A,CAPN3,ISPD,KRIT1,AIFM1,LARGE1,CRLF1,CFL2,ADGRG1,CHN1,RAB33A,TPP1,NIPBL,CCDC151,CNTN1,PREPL,C2CD2,CSF3R,ARHGEF10,CNTNAP2,RUBCN,CX3CR1,RIPOR2,DCAF8,HDAC4,MATR3,KIAA0586,DNAL1,DNAJC6,DCTN1,SACS,ARNT2,DLG2,DMD,DMPK,DNM2,SLC12A6,DSCAM,GNE,DTNA,DNAJB6,DNM1L,EDN3,EDNRB,ATL1,SEMA3D,OPTN,EGFR,TENM1,BSCL2,ELN,C8orf37,COQ7,ERBB2,ERBB4,ERCC2,CDHR1,ETV1,EYA1,F8,TUBB3,ZMYND10,FKTN,FGF14,FGFR1,FGFR3,MAD2L2,FHL1,SEC23B,FLNC,POMT1,APOPT1,MEGF10,GAA,GABRA3,GALC,B4GALNT1,ERAP1,SEPT9,INPP5K,GCK,TUBA8,GFAP,PPARGC1A,GJB1,GLDC,GNAS,PARD3B,GSN,ELOVL5,AGBL5,IDH3B,GAREM2,TMEM240,IL12A,IBA57,ITGA7,JAK2,KCND3,KCNH1,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF5A,KIT,STXBP5,LAMA2,LAMP2,LIFR,LIG4,LMO1,MAG,MAPT,MSR1,MTTP,MYCN,MYH7,NEFH,NEK1,NF1,NOS1,NTRK3,OCRL,CHAMP1,OPA1,TREM2,PDE4D,PDGFRA,PDYN,PGAM2,SERPINI1,NALCN,A2ML1,SNX10,RETREG1,PLEC,PLP1,PMP22,PSAT1,PMS2,PRRX1,POLG,POLR2F,PPP2R2B,PRKCG,HYDIN,PRPH,NDUFS7,APTX,LAMA1,PIGG,PTCH1,BDNF-AS,PTH1R,PEX2,PEX5,PYGM,SH3TC2,RET,REV3L,PRRT2,RGR,KIF7,RLBP1,RNASEL,SETD5,MYH14,ROM1,RPE65,FBXW7,LRRK2,RYR1,SALL1,SBF1,ATXN1,ATXN2,SCN2A,SCN8A,PRCD,SCP2,SLC30A10,FOXRED1,SH3BP2,FUZ,NUBPL,PEX26,SLC6A8,SLC6A9,RAB3GAP1,SLC11A1,SMARCD3,SNAP25,SNRPN,DOP1A,SOX2,SOX3,SPATA7,ZCCHC24,SOX10,EMC1,ARHGAP26,KIF1B,ZC4H2,SS18,ELOVL4,TTBK2,KLHL7,FGD4,ABCC8,VPS13A,ASTN2,TAC3,TACC1,SEMA4A,ALG1,TRIM2,SZT2,AHCYL2,ATP13A2,DICER1,ZFPM2,CRB1,MTMR14,TK2,DDHD1,TLR4,ERCC6L2,TNFRSF1B,KAT6B,PIK3R5,TPM2,TPM3,PDSS1,AMACR,TSC1,ANO5,TSC2,TTPA,TUB,BEST1,WIPF1,CLIP2,WRN,KLC2,XRCC4,LGI4,CFAP298,AGMO,REEP1,POLR3H,WNK1,MFF,GJC2,NLRP3,RNF170,SNX14,AAAS,GAN" Human Phenotype HP:0002079 Hypoplasia of the corpus callosum 4.71E-04 1.00E+00 4.60E-02 4.27E-01 76 262 "ARID1A,HACE1,KCNT1,AMPD2,AMT,KCNAB2,KIF1A,SYNJ1,ISPD,AIFM1,AP4M1,LARGE1,EARS2,ZEB2,ARNT2,DNM1,DMPK,TRAPPC9,ATL1,WAC,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,STAMBP,AP4B1,GABRB1,GABRB3,AHDC1,GLDC,GLUL,GNAO1,GPT2,PCLO,MFSD2A,RBPJ,DOCK7,IBA57,TUBB2B,KCNQ2,KIF2A,KIF5C,MEF2C,NEXMIF,NFIA,TREM2,PAX6,GPSM2,FA2H,PIGG,FAT4,KIF7,SLC1A2,SLC6A8,SLC6A9,RAB3GAP1,SMARCA4,SMARCE1,UNC80,SON,SOX2,SOX3,SOX11,EMC1,SPTAN1,POGZ,STXBP1,DDHD2,TCF4,TUBB2A,POLR3H,TUBA1A,GJC2,AP3B2" Human Phenotype HP:0006978 Dysmyelinating leukodystrophy 4.83E-04 1.00E+00 4.60E-02 4.27E-01 5 5 "PLP1,FA2H,POLG,POLR2F,SOX10" Human Phenotype HP:0025373 Interictal EEG abnormality 4.83E-04 1.00E+00 4.60E-02 4.27E-01 5 5 "KCNQ2,KCNQ3,PRRT2,SCN2A,SCN8A" Human Phenotype HP:0040168 "Focal seizures, afebril" 4.83E-04 1.00E+00 4.60E-02 4.27E-01 5 5 "KCNQ2,KCNQ3,PRRT2,SCN2A,SCN8A" Human Phenotype HP:0002372 Normal interictal EEG 4.83E-04 1.00E+00 4.60E-02 4.27E-01 5 5 "KCNQ2,KCNQ3,PRRT2,SCN2A,SCN8A" Human Phenotype HP:0000496 Abnormality of eye movement 4.93E-04 1.00E+00 4.62E-02 4.29E-01 302 1271 "ARID1A,ADAR,KLRC4,ADD1,ADD3,KIDINS220,HECW2,HACE1,WDR35,CC2D2A,PLA2G6,ALK,BIN1,ANK1,KCNAB2,ALS2,SLC7A14,PRX,CASK,CDK13,ASCL1,ASPA,PTCH2,ATM,ATP1A2,ATP1A3,STX16,ATP2B3,ALDH7A1,KIF1A,BBS2,BCS1L,FGF17,PROM1,SYNJ1,CACNA1G,CFAP410,CA4,CA8,CACNA1A,CACNB4,AP4M1,LRBA,CDC42,LARGE1,NOG,COPB2,ADGRG1,CHN1,CLCN4,NRXN1,TPP1,FBXO7,NIPBL,CNGA3,WHRN,COL11A2,SH2B1,CRYBB1,SEC24C,CTNND2,RUBCN,EARS2,KIAA0586,DNAJC6,DCTN1,ZEB2,B3GAT3,KIAA0753,BLOC1S6,SACS,ARNT2,DLG3,RAB39B,DMPK,MED12,DNM2,SLC12A6,DPP6,ATN1,DTNA,DNM1L,WDPCP,EDNRB,LPAR6,ELN,C8orf37,EMX2,VPS13B,ERCC2,CDHR1,APC2,ADGRV1,WAC,ACSL4,TUBB3,TUBB4A,CEP78,FKTN,STRADA,FGF14,FGFR1,FGFR3,MAD2L2,NOP56,POMT1,APOPT1,GABRA3,CHL1,GALC,B4GALNT1,ERAP1,ATP8A2,INPP5K,TUBGCP4,SRCAP,AHDC1,GFAP,MMADHC,GJB1,GK,GLRB,GNAS,GP1BB,GRM1,ELOVL5,AGBL5,HMX1,ATCAY,IDH3B,RBPJ,TMEM240,IL12A,TUBB2B,ITGA7,KCND3,KIF2A,KIF5A,L1CAM,LAMA2,LIG4,LMO1,MAG,MAPT,MEF2C,POC1B,MITF,MOBP,MOG,MTR,MYCN,MYH3,MYH7,MYO5A,MYO7A,NEXMIF,NDP,NF1,NFIX,NTRK3,OCRL,CHAMP1,OPA1,OPHN1,TREM2,PAX6,PDE4D,PDYN,SERPINI1,NALCN,A2ML1,SNX10,PLEC,PLP1,PMP22,MAGEL2,FA2H,POLG,POLR2F,PPP2R2B,KANSL1,CEP41,PRKCG,MASP1,NDUFS7,APTX,LAMA1,PTCH1,PEX2,PEX5,TMEM231,SH3TC2,RET,REV3L,PRRT2,RGR,KIF7,RLBP1,SETD5,ALG9,ROM1,RPE65,FBXW7,RYR1,SALL1,SBF1,ATXN1,ATXN2,ATXN7,SCN8A,PRCD,SCP2,FOXRED1,KIF21A,ARX,FUZ,NUBPL,ZNF365,SLC1A3,PEX26,SLC6A8,SLCO1A2,SMARCA4,SMARCE1,IFT122,SNCA,MBD5,SNRPN,UNC80,SON,SOX2,SOX3,SOX5,SPATA7,SOX10,SOX11,EMC1,ZNF423,KIF1B,IQSEC2,POGZ,ZC4H2,ELOVL4,TTBK2,STXBP1,KLHL7,ABCC8,VAMP1,VPS13A,ASTN2,SEMA4A,DDHD2,ROBO3,CAMTA1,TAF6,TBX15,TCF4,SATB2,RPGRIP1L,TCF12,SYNE1,SLC19A3,NSD1,ATP13A2,CRB1,AP4E1,MTMR14,TK2,TLR4,ERCC6L2,KAT6B,PIK3R5,TPM2,TPM3,TRPS1,KCNE5,TTPA,TUB,HIRA,UBE3A,UCHL1,FRRS1L,DNAJC12,VLDLR,BEST1,CLIP2,NSD2,PORCN,XRCC4,LGI4,ZIC1,ZBTB16,TMEM237,POLR3H,MFF,UBE3B,KAT6A,GJC2,JMJD1C,RSPRY1,SNX14,GAN" Mouse Phenotype MP:0003635 abnormal synaptic transmission 1.61E-45 1.29E-41 1.29E-41 1.23E-40 382 918 "SYN3,ASIC1,DSCAML1,SLITRK1,ADCY8,ADCYAP1R1,ADD2,SLC12A5,ADORA1,ADRA1D,LRFN2,KIDINS220,MTA3,GPR158,SORCS2,LRRC7,SEMA6A,KCNT1,DOC2A,PPFIA2,CNIH2,APBA2,DDO,APP,AQP4,MADD,CASK,ARNTL,ARRB1,CADPS,ASPA,CHRD,TMEM108,ATP1A2,ATP1A3,ATP2A2,ATP2B2,ADGRB3,RGS9,HCN2,KSR1,CDK5R1,SYNJ1,ST3GAL5,BSN,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CACNB4,CALB2,KALRN,CAMK2A,CAMK2B,CBLN1,SHISA7,CCK,CCKBR,CD81,CDH8,LGI1,DLGAP2,CACNA2D2,CHGA,CHGB,CHRM1,CHRM4,CHRNA4,RAB3C,CHRNB2,DLGAP3,PLAA,CLCN3,NRXN1,NRXN2,SLC24A2,ARHGEF6,CNR1,PICK1,AKAP5,MAGED1,ZNF521,PNKD,CRMP1,SLC32A1,FEZ1,NCAN,SLITRK5,CALY,ERC2,CTNND2,RIMS2,CYBB,ARHGAP32,SNPH,DGKB,DAPK1,SIRPA,DBT,PLEKHM1,CNIH3,KIAA0319,BLOC1S6,LYPD1,PLPPR4,SNAP91,SV2B,SV2A,SRGAP3,DLG2,DLG3,DLG4,GRIN3A,DNM1,OLIG1,SHANK1,CPEB2,SLC12A6,DPP6,DRD1,SEZ6L2,EDNRA,EEF1A2,CACNG7,EFNA2,EFNA3,EFNB3,MBNL2,EGR3,ELAVL3,ELAVL4,TMEM35A,EN2,OLIG2,ENO2,SEZ6,KCNMB2,EPS8,ERBB2,ERBB4,ADGRV1,EZH1,NRN1,CLVS1,FABP7,CACNG3,CACNG2,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,FOXO3,DPYSL4,NBEA,PDLIM5,CAMKK2,CSPG5,B3GAT1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,JPH4,ARPP21,GALR1,DISC1,STARD10,CPLX2,CPLX1,DNER,GFAP,GFRA1,PCDH17,C1QL1,PPARGC1A,GLUL,DCLK2,GNAO1,GNAS,GPD2,ATF7,MCHR1,GPR37,PCLO,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,NR3C1,GRM1,GRM2,GRM5,GRM7,GRM8,PTPN5,GSTM5,IL1RAPL1,IGSF21,FRMD5,HRH3,HLF,ACOT7,SYNPO,HNMT,IRF8,IL6ST,LRRTM3,LRRTM1,ITPKA,KCNA1,KCNA2,KCND2,KCNJ9,KCNJ10,KCNK3,KCNMA1,KCNQ2,KIF5A,KIT,STXBP5,L1CAM,LAMA2,MAG,MAOB,MAP6,MAPT,MAT2A,MBD1,MBP,MEF2C,MITF,AFDN,GIT1,MYO5A,NCAM1,NELL2,NOS1,NOVA2,NPPA,NRCAM,NTRK2,IGSF11,OPHN1,OPRL1,PAH,PAK3,PAX6,PCDH9,PDE4B,TMOD2,ZDHHC8,NLGN3,SERPINE2,NALCN,FTO,PACSIN1,SH3KBP1,PPP1R1A,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK9,MAPK10,SLC26A11,PRODH,RELN,PTN,PTPRE,PTPRZ1,RAB3A,RASGRF1,KHDRBS2,RET,PRRT2,MRAP2,LRRK2,KCNIP3,STX1B,RYR3,DGLUCY,ATXN1,ATXN7,SCN4B,LRRTM4,SCN8A,ELMOD1,PPP1R9A,SH3GL2,SH3GL3,CPEB3,SLITRK3,BCAN,NLGN1,CLSTN1,SLC1A3,SLC6A1,SLC6A8,SLC6A9,SLC8A2,RAB3GAP1,SLC8A3,CCDC88A,SHANK2,NAPB,SORCS3,SNAP25,SNCB,SNCA,TNIK,SP4,LHFPL4,NPAS3,SST,SSTR1,SSTR2,NCDN,MAPK8IP3,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,TACR1,ADGRL3,WWC1,TCF4,CRTC1,AP4E1,ICAM5,RIMBP2,TNFRSF1B,SEZ6L,PRMT8,TRPC3,NTSR2,TSC1,TSC2,UBE3A,UCHL1,VAV2,VGF,VLDLR,ZIC2,KCNT2,ELFN1,CELF4,REEP1,DPYSL5,ANKS1B,LRP8,RNF103,SLC17A7,KCNAB1,TMEM163,SLC17A6,FZD3,NETO2,NETO1,JPH3" Mouse Phenotype MP:0002206 abnormal CNS synaptic transmission 3.34E-44 2.67E-40 1.33E-40 1.28E-39 307 683 "SYN3,ASIC1,DSCAML1,ADCY8,ADCYAP1R1,ADD2,SLC12A5,ADORA1,ADRA1D,LRFN2,KIDINS220,MTA3,GPR158,LRRC7,SEMA6A,DOC2A,PPFIA2,CNIH2,APBA2,APP,MADD,ARRB1,CADPS,ASPA,CHRD,TMEM108,ATP1A3,ATP2A2,ATP2B2,ADGRB3,RGS9,KSR1,CDK5R1,SYNJ1,BSN,WASF1,BAIAP3,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALB2,KALRN,CAMK2A,CAMK2B,CBLN1,SHISA7,CCK,CCKBR,CDH8,LGI1,DLGAP2,CACNA2D2,CHRM1,CHRM4,CHRNA4,RAB3C,CHRNB2,DLGAP3,PLAA,CLCN3,NRXN1,NRXN2,SLC24A2,ARHGEF6,CNR1,PICK1,AKAP5,ZNF521,CRMP1,SLC32A1,NCAN,CALY,ERC2,CTNND2,CYBB,ARHGAP32,DGKB,DAPK1,SIRPA,PLEKHM1,CNIH3,KIAA0319,LYPD1,PLPPR4,SNAP91,SV2B,SV2A,SRGAP3,DLG2,DLG3,DLG4,GRIN3A,DNM1,OLIG1,SHANK1,SLC12A6,DPP6,DRD1,SEZ6L2,EDNRA,CACNG7,EFNA2,EFNA3,EFNB3,MBNL2,EGR3,TMEM35A,OLIG2,ENO2,SEZ6,EPS8,ERBB2,ERBB4,ADGRV1,EZH1,NRN1,CLVS1,FABP7,CACNG3,CACNG2,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,FOXO3,DPYSL4,NBEA,PDLIM5,CAMKK2,CSPG5,B3GAT1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,JPH4,GALR1,DISC1,STARD10,CPLX2,CPLX1,DNER,GFAP,PCDH17,C1QL1,DCLK2,ATF7,GPR37,PCLO,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,NR3C1,GRM1,GRM2,GRM5,GRM7,GRM8,PTPN5,IL1RAPL1,IGSF21,FRMD5,ACOT7,SYNPO,IRF8,LRRTM3,LRRTM1,ITPKA,KCNA1,KCNA2,KCNJ10,KCNMA1,KCNQ2,KIF5A,STXBP5,L1CAM,LAMA2,MAG,MAP6,MAPT,MAT2A,MBD1,MBP,MEF2C,AFDN,GIT1,MYO5A,NCAM1,NELL2,NOS1,NOVA2,NRCAM,NTRK2,IGSF11,OPHN1,OPRL1,PAK3,PAX6,PCDH9,PDE4B,TMOD2,ZDHHC8,NLGN3,SERPINE2,PACSIN1,PPP1R1A,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK9,SLC26A11,RELN,PTN,PTPRZ1,RAB3A,RASGRF1,PRRT2,KCNIP3,STX1B,RYR3,ATXN1,ATXN7,SCN4B,LRRTM4,ELMOD1,PPP1R9A,SH3GL2,SH3GL3,CPEB3,SLITRK3,BCAN,NLGN1,CLSTN1,SLC1A3,SLC6A1,SLC6A9,SLC8A2,RAB3GAP1,CCDC88A,SHANK2,NAPB,SORCS3,SNAP25,TNIK,SP4,LHFPL4,NPAS3,SST,NCDN,MAPK8IP3,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT5,WWC1,TCF4,AP4E1,ICAM5,RIMBP2,TNFRSF1B,SEZ6L,TRPC3,NTSR2,TSC1,TSC2,UBE3A,UCHL1,VGF,VLDLR,ZIC2,ELFN1,CELF4,DPYSL5,ANKS1B,LRP8,RNF103,SLC17A7,KCNAB1,TMEM163,SLC17A6,FZD3,NETO2,NETO1,JPH3" Mouse Phenotype MP:0002882 abnormal neuron morphology 2.48E-32 1.98E-28 6.60E-29 6.31E-28 534 1589 "ABR,SYN3,DSCAML1,SLC12A5,UNC5A,LRFN2,ADRB2,KIDINS220,GPR158,SORCS2,CC2D2A,PLA2G6,LRRC7,SPARCL1,SEMA6A,ALCAM,BCAR3,ABCD2,MRTFA,ANK1,ANK3,SEMA7A,CNTNAP1,APAF1,APBB1,APBB2,GAS7,ALS2,APP,SEMA4G,PRX,MADD,SPTBN4,CADPS,ASCL1,NCOA1,NUMB,ASTN1,TMEM108,ATM,ATP1A3,ATP2B2,KIF1A,ADGRB3,BBS2,RGS9,BCL2L2,FGF17,NRP2,BID,PROM1,BMPR1B,CDK5R1,SYNJ2,SGCE,CACNA1G,BSN,WASF1,CDK5R2,CACNA1A,CACNA1D,CACNB2,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CANX,BRSK2,ISPD,CBLN1,AIFM1,CD86,CD81,SEPT7,CDH2,CDH8,DCLK1,ARHGAP33,DLGAP2,NOG,CRLF1,NUMBL,CACNA2D2,GPR37L1,ADGRG1,CHGB,ASIC3,CHM,CHN1,CHN2,CHRNA4,JAM2,SLIT2,LHX2,PLAA,CLCN3,CLU,TPP1,NGEF,VAX2,QKI,TMEM184B,CNGA3,ARHGEF6,CNR1,CNTFR,CNTN1,WHRN,SLC4A7,GAL3ST1,ZNF521,CP,CLOCK,CRMP1,CRY2,NCOR1,NCOR2,CLIP3,AATK,CSF1,CSF1R,LRIG1,VCAN,CST3,PLXNA4,SLITRK5,ERC2,CTNND1,RIMS2,CX3CR1,ARHGAP32,SNPH,FRMPD4,KIF26A,DGKB,BRINP1,SIRPA,DBN1,DCC,DNAJC6,DCTN1,HEPH,MAGI2,GSDME,SNAP91,SRGAP3,DLG3,DLG4,GRIN3A,DMD,DNM1,OLIG1,NYAP1,SHANK1,CPEB2,SLC12A6,DPYSL2,DRD1,DRP2,DSCAM,DTNA,DYRK1A,DNM1L,USH1C,EDIL3,EDN3,EDNRB,EEF1A2,HEYL,EFNA2,EFNA3,EFNB3,CELSR3,EGFR,MBNL2,ABI2,EGR3,PLXNC1,ELAVL4,EML1,C8orf37,EMX2,EN2,OLIG2,ENO2,SEZ6,EPHA5,EPHB1,GPHN,ERBB2,ERBB4,ERCC2,APC2,ETV1,CEND1,ADGRV1,EYA1,NRN1,CACNG2,TUBB3,FGF13,FGF14,ACTL6B,FGFR1,FGFR3,FOXG1,VTI1B,EVL,FLT1,DPYSL4,NBEA,POMT1,SMC2,STAMBP,CAMKK2,TBR1,AP4B1,BRSK1,FYN,MEGF11,MEGF10,GABBR1,GABRA1,GABRA5,CHL1,GABRB3,GABRG2,GALC,B4GALNT1,NKX6-2,IP6K3,GAP43,ATP8A2,SRRM4,GBX2,GFAP,GFRA1,GFRA2,PCDH17,C1QL1,PPARGC1A,KIRREL3,GJB1,GLI2,GLRB,DCLK2,GPT2,GPM6A,GPM6B,GPR37,PCLO,GRIA1,GRIA2,GRID1,GRIK4,GRIN1,NR3C1,GRM7,RNF165,MFSD2A,GUCY1A1,IGSF21,HAPLN2,ACOT7,HMX1,TLX1,HPCA,CPT1C,ATCAY,IGF1,ZIC5,RBPJ,HES5,INSM1,LRRTM3,LRRTM1,KCND2,KCNJ10,KCNMA1,KIF2A,KIF5A,KIF5C,KIT,KLC1,L1CAM,LAMA2,LIFR,SMAD9,MAG,MAP2,MAP6,MAPT,MBD1,MBNL1,MBP,MDM4,SHC3,PPM1L,MITF,MKLN1,AFF1,AFDN,MOG,MOV10,GIT1,BLOC1S2,ADAM22,MSR1,MYCN,MYO5A,MYO6,MYO7A,NAP1L1,NCAM1,NDP,RCOR2,NEFH,NEUROD1,NF1,NFIA,NFE2L2,NHLH1,NKX2-2,NOS1,NPR2,NRCAM,NRDC,HCN1,NTRK2,NTRK3,OPA1,OPHN1,CLDN11,TREM2,PAX6,PCDH9,PDE4B,ENPP2,ZDHHC8,ABCB1,NLGN3,SEMA5B,TMIE,RETREG1,GPSM2,PLEC,PLP1,PLXNB1,ANKRD16,PMP2,PMP22,MBOAT7,PACSIN1,FA2H,FAT3,POLG,POU3F2,POU3F4,PRKACB,PROX1,PRPH,RELN,KLK6,LAMA1,PTCH1,PTPN13,PEX2,PEX5,SH3TC2,FEZF2,KHDRBS2,RDX,SLC6A15,CRTAC1,RET,PRRT2,RFX3,RFX4,KIF7,RLBP1,RIC8B,ROBO1,ROBO2,ROM1,RORB,RPE65,FBXW7,GLDN,ACER3,LRRK2,LGR4,RXRA,STX1B,ATXN1,ATXN2,ATXN7,SCN8A,SH3GL2,SH3GL3,ARX,CPEB3,FUZ,SLITRK3,NLGN1,CLSTN1,SLC1A2,SLC1A3,SLC4A3,PREX2,SLC6A8,SIRT2,CCDC88A,SHANK2,SLC12A2,NAPB,TET1,SLIT1,CPEB4,SMARCC2,IFT122,SNCA,MBD5,MYO16,SOX1,SOX2,TNIK,SPATA7,KIF21B,SOX10,SOX11,SP2,NMNAT2,LHFPL4,MYCBP2,SPP1,ZNF423,SPTAN1,KIF1B,NFASC,CLSTN2,SMOC1,SSTR1,SSTR2,EPB41L3,ERBIN,MAPK8IP3,STAU1,ELOVL4,SEPT8,STX1A,SULF2,STXBP1,MLC1,FGD4,SYNE2,ARHGEF9,PLCB1,SYN1,SYN2,MTCL1,SEMA4A,DDHD2,ROBO3,CAMTA1,UNC5D,CNTN2,AGTPBP1,ATMIN,CUX2,ZEB1,TRIM2,USP22,SYNE1,SLC19A3,ATP13A2,SIRT1,CRB1,ZNF106,HHIP,THRA,ENHO,HEY1,TLR4,NR2E1,TNR,TP53BP2,RBFOX2,CDK20,WBP2,NR2C2,PRMT8,TRIO,TRPC3,TSC1,TSC2,TUB,HEPACAM,UBE3A,UCHL1,UGT8,VAV2,VGF,VLDLR,LGI4,ZIC2,ZNF24,TRIM9,ELFN1,CRB2,REEP1,DPYSL5,SPIRE1,SLC30A3,MAP3K12,LRP8,GDPD5,PRDM8,TUBA1A,PCDH15,SLC17A7,TMEM163,SLC17A6,PDSS2,EPM2A,RTN4,PAK5,GJC2,VANGL2,MSRB3,NETO1,ST8SIA2,GAN" Mouse Phenotype MP:0002063 abnormal learning/memory/conditioning 4.82E-31 3.85E-27 9.62E-28 9.20E-27 285 703 "SYN3,ASIC1,ADCY8,ADCYAP1R1,ADD2,SLC12A5,FZD9,ADORA2A,PTCHD1,ADRA1D,ADRA1B,LRFN2,KCTD16,PLA2G6,LRRC7,DOC2A,AMPH,APBA2,APBB1,KCNAB2,ALS2,APP,CDC14B,CHRD,NCOA1,TMEM108,ATM,ATP1A1,ATP1A2,ATP1A3,STX16,ADGRB3,RGS9,BCL2L2,BCL7A,KSR1,CDK5R1,SGCE,CACNA1G,WASF1,CA8,CACNA1B,KALRN,CAMK2A,CAMK2B,CANX,CAST,SHISA7,NEURL1,DLGAP2,GPR37L1,CHRNA4,CHRNB2,TAOK2,CLCN3,NRXN1,SLC24A2,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRMP1,NCOR1,CSF1R,FEZ1,CNTNAP2,ERC2,CTNND2,CYBB,ARHGAP32,DGKB,BRINP1,SIRPA,DBN1,LYPD1,SRGAP3,DLG3,DLG4,OLIG1,SHANK1,SLC12A6,DRD1,DSCAM,RCAN1,DYRK1A,EDIL3,EFNA2,EFNA3,MBNL2,ABI2,TMEM35A,EML1,EN2,ENO2,RCAN2,SEZ6,ERBB4,ERCC2,NRN1,FABP7,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,B3GAT1,TBR1,FYN,GABBR1,GABRA1,GABRA2,GABRA5,CHL1,GABRB1,GABRB3,GABRG2,GAD2,JPH4,GALR1,IP6K3,DISC1,CPLX2,GFAP,GHR,C1QL1,GNAS,PRLHR,MCHR1,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRIN2C,GRM1,GRM5,GRM7,GRM8,NXPH3,HRH3,SYNPO,CPT1C,HSD17B1,HTR5A,LRRTM1,KCNC1,KCNJ11,KCNMA1,L1CAM,LSAMP,NAT8L,MAOB,MAP2,MAPT,MBD1,MBP,ADAM11,GIT1,MYO5A,FXYD6,NCAM1,IDNK,NF1,NOS1,NPY,NPTX2,NRCAM,NRDC,HCN1,NTRK2,OPA1,OPHN1,OPRL1,OXTR,PAH,PAK3,PCDH9,PDE4B,PDE1B,PDYN,GPR85,PENK,TMOD2,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,FA2H,SH3KBP1,PRKACB,PKIA,PRKCB,PRKCG,MAPK3,RELN,PTPRG,PTPRZ1,RASGRF1,RGS4,RGS7,CARF,RORB,ZC3H14,CNTNAP3,KCNIP3,RYR3,ATXN1,ITSN1,ARX,CPEB3,SLC6A1,SLC6A8,SLC6A9,SLC8A2,CCDC88A,SHANK2,MTERF2,TET1,SORCS3,SNAP25,MBD5,ANKFN1,TNIK,KIF21B,SP4,NPAS3,CLSTN2,SST,SSTR2,NCDN,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYT4,TACR1,DDHD2,TAF6,WWC1,WSCD1,TCF4,DMXL2,CRTC1,ATP13A2,SLC44A1,THRA,ICAM5,NR2E1,PRMT8,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,NDRG4,ZNF142,SPIRE1,LRP8,GDPD5,RNF103,TUBA1A,NAV2,SLC17A7,KCNAB1,TMEM163,SLC17A6,EPM2A,FZD3,PAK5,GJC2,CERS6,AAAS,NETO1,ST8SIA2,SLC4A10,JPH3" Mouse Phenotype MP:0014114 abnormal cognition 6.45E-31 5.15E-27 1.03E-27 9.84E-27 285 704 "SYN3,ASIC1,ADCY8,ADCYAP1R1,ADD2,SLC12A5,FZD9,ADORA2A,PTCHD1,ADRA1D,ADRA1B,LRFN2,KCTD16,PLA2G6,LRRC7,DOC2A,AMPH,APBA2,APBB1,KCNAB2,ALS2,APP,CDC14B,CHRD,NCOA1,TMEM108,ATM,ATP1A1,ATP1A2,ATP1A3,STX16,ADGRB3,RGS9,BCL2L2,BCL7A,KSR1,CDK5R1,SGCE,CACNA1G,WASF1,CA8,CACNA1B,KALRN,CAMK2A,CAMK2B,CANX,CAST,SHISA7,NEURL1,DLGAP2,GPR37L1,CHRNA4,CHRNB2,TAOK2,CLCN3,NRXN1,SLC24A2,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRMP1,NCOR1,CSF1R,FEZ1,CNTNAP2,ERC2,CTNND2,CYBB,ARHGAP32,DGKB,BRINP1,SIRPA,DBN1,LYPD1,SRGAP3,DLG3,DLG4,OLIG1,SHANK1,SLC12A6,DRD1,DSCAM,RCAN1,DYRK1A,EDIL3,EFNA2,EFNA3,MBNL2,ABI2,TMEM35A,EML1,EN2,ENO2,RCAN2,SEZ6,ERBB4,ERCC2,NRN1,FABP7,PPP1R1B,FGF12,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,B3GAT1,TBR1,FYN,GABBR1,GABRA1,GABRA2,GABRA5,CHL1,GABRB1,GABRB3,GABRG2,GAD2,JPH4,GALR1,IP6K3,DISC1,CPLX2,GFAP,GHR,C1QL1,GNAS,PRLHR,MCHR1,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRIN2C,GRM1,GRM5,GRM7,GRM8,NXPH3,HRH3,SYNPO,CPT1C,HSD17B1,HTR5A,LRRTM1,KCNC1,KCNJ11,KCNMA1,L1CAM,LSAMP,NAT8L,MAOB,MAP2,MAPT,MBD1,MBP,ADAM11,GIT1,MYO5A,FXYD6,NCAM1,IDNK,NF1,NOS1,NPY,NPTX2,NRCAM,NRDC,HCN1,NTRK2,OPA1,OPHN1,OPRL1,OXTR,PAH,PAK3,PCDH9,PDE4B,PDE1B,PDYN,GPR85,PENK,TMOD2,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,FA2H,SH3KBP1,PRKACB,PKIA,PRKCB,PRKCG,MAPK3,RELN,PTPRG,PTPRZ1,RASGRF1,RGS4,RGS7,CARF,RORB,ZC3H14,CNTNAP3,KCNIP3,RYR3,ATXN1,ITSN1,ARX,CPEB3,SLC6A1,SLC6A8,SLC6A9,SLC8A2,CCDC88A,SHANK2,MTERF2,TET1,SORCS3,SNAP25,MBD5,ANKFN1,TNIK,KIF21B,SP4,NPAS3,CLSTN2,SST,SSTR2,NCDN,STX1A,ARHGEF9,PLCB1,SYN1,ARC,SYN2,SYT4,TACR1,DDHD2,TAF6,WWC1,WSCD1,TCF4,DMXL2,CRTC1,ATP13A2,SLC44A1,THRA,ICAM5,NR2E1,PRMT8,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,NDRG4,ZNF142,SPIRE1,LRP8,GDPD5,RNF103,TUBA1A,NAV2,SLC17A7,KCNAB1,TMEM163,SLC17A6,EPM2A,FZD3,PAK5,GJC2,CERS6,AAAS,NETO1,ST8SIA2,SLC4A10,JPH3" Mouse Phenotype MP:0001392 abnormal locomotor behavior 8.95E-31 7.14E-27 1.19E-27 1.14E-26 528 1585 "ABR,ACHE,ADCY5,SLITRK1,ADCYAP1R1,SLC12A5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,PLA2G6,C1QTNF1,LRRC7,ABCD2,UNC79,ALK,AMPD2,AMPD3,OGT,ANK3,PPFIA2,CNTNAP1,APAF1,APBA2,APC,ALS2,APP,PRX,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,NUMB,CCAR2,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,ADAM23,ADGRB2,RGS9,BCL2L2,HCN2,BCS1L,FGF17,BID,PROM1,CDK5R1,SYNJ1,MTMR2,CACNA1G,BSN,MYRF,FOXK1,CA8,CACNA1A,CACNA1B,DDR1,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2B,CANX,CAST,BRSK2,CBLN1,CCKBR,USP2,RGN,AIFM1,NEURL1,CD81,LGI1,DLGAP2,CDO1,CACNA2D2,CFL2,GPR37L1,ADGRG1,CHN1,CHRM1,CHRM4,CHRNA4,CHRNB2,PLAA,PPT2,CLCN3,NRXN1,NRXN2,CLU,TPP1,QKI,CNR1,CNTN1,WHRN,MAGED1,GAL3ST1,COX4I1,ZNF521,CP,CLOCK,CREM,CRY2,SLC32A1,NCOR1,ABCG1,CSF1R,FEZ1,PDE4DIP,CNTNAP2,APPL1,CTH,CYBB,GPRASP1,HDAC4,DGKB,DAPK1,BRINP1,DBT,DCC,DCTN1,BLOC1S6,SNAP91,SRGAP3,DLG3,DLG4,DMD,DNM1,OLIG1,SHANK1,SLC12A6,DRD1,ATN1,DSCAM,RCAN1,E2F5,E2F6,USH1C,EDIL3,ATL1,CACNG7,EFNA2,EFNA3,EFNB3,EGR3,EIF4G2,COPS4,MRNIP,BSCL2,TMEM35A,EML1,EN2,OLIG2,ENO2,RCAN2,SEZ6,ERBB2,ERBB4,ERCC2,NCALD,APC2,ETV1,PIPOX,CEND1,F3,F5,FABP7,CACNG3,CACNG2,ZIC4,FDFT1,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,ACTL6B,FGFR1,FGFR3,SUCO,FOXG1,CAP2,FOXO3,FLNC,SGIP1,NBEA,PDLIM5,FAM49B,KHDRBS3,BRSK1,FYN,DKK3,GAA,GABBR1,GABRA1,GABRA3,GABRA5,GABRB3,GABRG2,GAD1,GAD2,GALC,B4GALNT1,JPH4,IP6K3,DISC1,ATP8A2,STARD10,CPLX2,CPLX1,GATM,GCNT2,PPARGC1A,GJB1,HPGDS,GLI2,GLRB,GLS,GLUL,PCSK1N,GNAL,GNAO1,GNAS,GPT2,GPM6B,GPR22,MCHR1,GPR37,TPPP,GRIA1,GRIA2,GRIA4,PARD3B,GRIN1,GRIN2C,GRIN2D,NR3C1,ATE1,GRM1,GRM2,GRM5,GRM7,GRM8,CIT,KIF3A,GSTM5,MFSD2A,PSIP1,ATG4C,HAS2,NXPH3,FRMD5,HRH3,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,HTR2A,ATCAY,ZIC5,RBPJ,TUBB2B,LRRTM1,ITGA7,ITGAV,ITPKB,KCNA1,KCNA2,KCNB1,KCNC1,KCNH1,KCNJ3,KCNJ10,KCNJ11,KCNMA1,L1CAM,LAMA2,LAMP2,LIG4,LSAMP,MAG,NAT8L,MAOB,MAP6,MAPT,MBP,ADAM11,MEF2C,PPM1L,AFF1,MMP16,MN1,MOG,MOV10,GIT1,DBNL,MSI1,ADAM22,MSRA,MYCN,MYH6,MYO5A,MYO6,MYO7A,MYO9A,NDUFA5,NEUROD1,NEUROD2,NF1,NFIX,NOS1,NPY,NRCAM,NTRK2,NTRK3,OGG1,OPA1,OPHN1,OXTR,PAH,PCDH9,PDE4B,PDE1B,PDGFRA,PDYN,TMOD2,NLGN3,TMIE,PLCB2,FTO,PLP1,PCDH18,ANKRD16,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,POU3F4,PPP3CB,KANSL1,PRKAB2,MAPK3,EPDR1,HYDIN,PROX1,RELN,LAMA1,PTCH1,PTHLH,PTPRG,PEX2,PEX5,OXR1,ARID4A,FEZF2,KHDRBS2,RET,PRRT2,FIGN,RGS4,RGS7,ROBO2,RORB,RPE65,GLDN,ACER3,LRRK2,KCNIP3,STX1B,RYR1,RYR3,SATB1,ATXN1,ATXN2,ATXN7,SCN3A,SCN8A,ELMOD1,SH3GL2,ARX,CPEB3,FBXO11,CLSTN1,SLC1A2,SLC1A3,SLC4A3,PREX2,WDR47,SLC6A1,SLC6A8,SLC6A9,SIRT2,CCDC88A,SHANK2,SLC12A2,NAPB,SNAP25,SNCA,KIF13A,ANKFN1,SOX1,SOX2,TNIK,SOX10,SP4,ZNF423,BEX1,KIF1B,TSPYL2,NPAS3,NFASC,CLSTN2,ITPRID2,SMOC1,SST,SSTR1,SSTR2,EPB41L3,LRRC4,NCDN,STAU1,ELOVL4,SEPT8,STX1A,STXBP1,MLC1,VAMP1,VPS13A,PLCB1,SYPL1,TACR1,DDHD2,ROBO3,CAMTA1,ADGRL3,AGTPBP1,IQCE,ATMIN,TCF4,TCF7L2,ZEB1,TRIM2,USP22,TMEM151B,SLC19A3,ATP13A2,DICER1,SIRT1,CHST8,AP4E1,ZNF106,AKTIP,SLC44A1,THRA,ENHO,NACC2,TK2,TLR4,TNFRSF1B,CSMD1,TP53BP2,RBFOX2,SEZ6L,RASD2,WBP2,PRMT8,TRIO,TRPC3,NTSR2,TSC1,TSC2,TST,TTPA,UBE3A,UCHL1,FRRS1L,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,WNT7A,LGI4,ZIC1,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,REEP1,ANKS1B,FTSJ1,LRP8,TUBA1A,PCDH15,TMEM163,SLC17A6,PDSS2,EPM2A,PAK5,GJC2,CERS6,RNF170,VANGL2,AAAS,FXR1,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0001516 abnormal motor coordination/balance 4.62E-29 3.69E-25 5.27E-26 5.04E-25 327 864 "ABR,ACHE,ADCY5,ADRA1D,PLA2G6,ABCD2,ANK1,ANK3,PKP4,CNTNAP1,APBA2,GAS7,ALS2,APP,PRX,SPTBN4,ARNTL,ASPA,NCOA1,NUMB,ASTN1,ATM,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,ADAM23,BBS2,RGS9,BCL2L2,HCN2,BID,PROM1,BMP7,CDK5R1,SYNJ1,MTMR2,SGCE,CACNA1I,CACNA1G,BSN,WASF1,MYRF,CA8,CACNA1A,CACNB4,CALB1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CANX,CBLN1,CCKBR,CERS5,AIFM1,CACNA2D2,CFL2,GPR37L1,CHN1,CHRNB2,PLAA,PPT2,CLCN3,TPP1,QKI,CNR1,CNTN1,WHRN,AKAP5,GAL3ST1,IGDCC3,CP,PREPL,HAPLN1,CSF1R,CNTNAP2,CTNND2,CYBB,ARHGAP32,SNPH,BRINP1,DCC,DCTN1,BLOC1S6,DLG4,DMD,DNM1,SHANK1,SLC12A6,DRD1,DSCAM,DTNA,DTNB,E2F5,E2F6,USH1C,EDIL3,SEZ6L2,EEF1A2,CACNG7,EFNB3,CELSR3,MBNL2,EGR3,ELAVL3,ELAVL4,EML1,EN2,OLIG2,SEZ6,EPS8,ERBB2,ERCC2,APC2,ETV1,CEND1,F3,CACNG3,CACNG2,ZIC4,FDFT1,PRMT5,FGF12,FGF14,FGFR1,SUCO,AP4B1,GAA,GABRA1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,NKX6-2,SALL3,IP6K3,ATP8A2,SRRM4,CPLX2,CPLX1,DNER,PPARGC1A,GJB1,HPGDS,GLI2,GLRB,GNAO1,GNAS,GPM6B,GPR37,GRIA2,GRIA4,GRIN1,GRIN2C,GRM1,GRM2,GRM5,GRM7,GRM8,CIT,MFSD2A,NXPH3,ACOT7,HSD17B1,ATCAY,ITGAV,KCNA1,KCNA2,KCNC1,KCNJ10,KCNJ11,KCNK3,KCNMA1,KIF5A,KLC1,L1CAM,LAMA2,LIG4,LSAMP,MAG,MAPT,MBNL1,MBP,ADAM11,PPM1L,AFF1,MOG,GIT1,DBNL,MSI1,ADAM22,MYO5A,MYO6,MYO7A,NDUFA5,NEUROD1,NEUROD2,NF1,NFIX,NOS1,NOVA1,NRCAM,NRDC,NTRK2,NTRK3,OPA1,CLDN11,PAH,PCDH9,TMOD2,NLGN3,TMIE,PLCL1,JAKMIP1,PLP1,ANKRD16,PMP22,FA2H,POU3F4,MAPK10,SLC26A11,HYDIN,RELN,LAMA1,PTCH1,PTPRG,PTPRZ1,PEX2,PEX5,OXR1,PRRT2,FIGN,RGS4,RORB,EPHA10,GLDN,ACER3,LRRK2,STX1B,ATXN1,ATXN2,ATXN7,SCN8A,ITSN1,SH3GL2,ARX,SLC1A3,PREX2,SLC6A1,SLC6A8,SLC8A3,SIRT2,SHANK2,SLC12A2,NAPB,CPEB4,SNAP25,SNCA,MBD5,ANKFN1,SOX2,SOX10,SP4,ZNF423,KIF1B,NPAS3,NFASC,SSTR2,EPB41L3,NCDN,STXBP1,MLC1,VAMP1,VPS13A,SYT4,TACR1,MTCL1,DDHD2,ROBO3,CAMTA1,AGTPBP1,TRIM2,SYNE1,ATP13A2,ZNF106,THRA,ENHO,MTMR14,TLR4,RBFOX2,SEZ6L,RASD2,NR2C2,TRIO,TRPC3,TSN,TSC1,TSC2,TTPA,UBE3A,UCHL1,UGT8,VLDLR,CLIP2,LGI4,ZIC1,ELFN1,REEP1,SLC30A4,LRP8,PRDM8,RNF103,PCDH15,SLC17A7,SLC17A6,PDSS2,EPM2A,GJC2,CERS6,RNF170,VANGL2,AAAS,JPH3" Mouse Phenotype MP:0003491 abnormal voluntary movement 2.76E-28 2.20E-24 2.62E-25 2.51E-24 550 1702 "ABR,ACHE,ADCY5,SLITRK1,ADCYAP1R1,SLC12A5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,PLA2G6,C1QTNF1,LRRC7,ABCD2,UNC79,ALK,AMPD2,AMPD3,OGT,ANK3,PPFIA2,CNTNAP1,APAF1,APBA2,APC,ALS2,APP,PRX,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,NUMB,CCAR2,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,ADAM23,ADGRB2,RGS9,BCL2L2,HCN2,BCS1L,FGF17,BID,PROM1,CDK5R1,SYNJ1,MTMR2,CACNA1G,BSN,MYRF,FOXK1,CA8,CACNA1A,CACNA1B,DDR1,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CAMK2B,CANX,CAST,BRSK2,CBLN1,CCKBR,USP2,RGN,AIFM1,CD86,NEURL1,CD81,CDH8,LGI1,DLGAP2,CDO1,CACNA2D2,CFL2,GPR37L1,ADGRG1,CHN1,CHRM1,CHRM4,CHRNA4,CHRNB2,PLAA,PPT2,CLCN3,NRXN1,NRXN2,CLU,TPP1,QKI,CNR1,CNTN1,WHRN,MAGED1,GAL3ST1,COX4I1,ZNF521,CP,CLOCK,CREM,CRY2,SLC32A1,NCOR1,NCOR2,ABCG1,CSF1,TENM4,CSF1R,FEZ1,PDE4DIP,CNTNAP2,APPL1,CTH,CX3CR1,CYBB,GPRASP1,HDAC4,DGKB,DAPK1,BRINP1,DBT,DCC,DCTN1,BLOC1S6,SNAP91,SRGAP3,DLG3,DLG4,DMD,DNM1,OLIG1,SHANK1,SLC12A6,DRD1,ATN1,DSCAM,RCAN1,E2F5,E2F6,USH1C,EDIL3,ATL1,CACNG7,EFNA2,EFNA3,EFNB3,EGR3,EIF4G2,COPS4,MRNIP,BSCL2,TMEM35A,EML1,EN2,OLIG2,ENO2,RCAN2,SEZ6,ERBB2,ERBB4,ERCC2,NCALD,APC2,ETV1,PIPOX,CEND1,EYA1,F3,F5,FABP7,CACNG3,CACNG2,ZIC4,FDFT1,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,ACTL6B,FGFR1,FGFR3,SUCO,FOXG1,CAP2,FOXO3,FLNC,SGIP1,NBEA,PDLIM5,FAM49B,KHDRBS3,DLL3,BRSK1,FYN,DKK3,GAA,GABBR1,GABRA1,GABRA3,GABRA5,GABRB3,GABRG2,GAD1,GAD2,GALC,B4GALNT1,JPH4,IP6K3,DISC1,ATP8A2,SRRM4,STARD10,CPLX2,CPLX1,GATM,GCNT2,PPARGC1A,GJB1,HPGDS,GLI2,GLRB,GLS,GLUL,PCSK1N,GNAL,GNAO1,GNAS,GPT2,GPM6B,GPR22,MCHR1,GPR37,TPPP,GRIA1,GRIA2,GRIA4,PARD3B,GRIN1,GRIN2C,GRIN2D,NR3C1,ATE1,GRM1,GRM2,GRM5,GRM7,GRM8,CIT,KIF3A,GSTM5,MFSD2A,PSIP1,ATG4C,HAS2,NXPH3,FRMD5,HRH3,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,HTR2A,ATCAY,ZIC5,RBPJ,IL6R,TUBB2B,LRRTM1,ITGA7,ITGAV,ITPKB,KCNA1,KCNA2,KCNB1,KCNC1,KCNH1,KCNJ3,KCNJ10,KCNJ11,KCNMA1,KIF5A,L1CAM,LAMA2,LAMP2,LIG4,LSAMP,MAG,NAT8L,MAOB,MAP6,MAPT,MBP,ADAM11,MEF2C,PPM1L,AFF1,MMP16,MN1,MOG,MOV10,GIT1,DBNL,MSI1,ADAM22,MSRA,MYCN,MYH6,MYO5A,MYO6,MYO7A,MYO9A,NDUFA5,NEFH,NEUROD1,NEUROD2,NF1,NFIX,NOS1,NPY,NRCAM,NTRK2,NTRK3,OGG1,OPA1,OPHN1,OXTR,PAH,PCDH9,PDE4B,PDE1B,PDGFRA,PDYN,TMOD2,NLGN3,TMIE,PLCB2,FTO,PLP1,PCDH18,ANKRD16,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,POU3F4,PPP3CB,KANSL1,PRKAB2,MAPK3,EPDR1,MAPK7,HYDIN,PROX1,RELN,LAMA1,PTCH1,PTHLH,PTPRG,PEX2,PEX5,SH3TC2,OXR1,ARID4A,FEZF2,KHDRBS2,RET,PRRT2,FIGN,RGS4,RGS7,ROBO2,RORB,RPE65,GLDN,ACER3,LRRK2,KCNIP3,STX1B,RYR1,RYR3,SATB1,ATXN1,ATXN2,ATXN7,SCN3A,SCN8A,ELMOD1,SH3GL2,ARX,CPEB3,FBXO11,CLSTN1,SLC1A2,SLC1A3,SLC4A3,PREX2,WDR47,SLC6A1,SLC6A8,SLC6A9,SIRT2,CCDC88A,SHANK2,SLC12A2,NAPB,SNAP25,MAPKBP1,SNCA,KIF13A,ANKFN1,SNRPN,SOX1,SOX2,TNIK,SOX10,SP4,NMNAT2,ZNF423,BEX1,KIF1B,TSPYL2,NPAS3,NFASC,CLSTN2,ITPRID2,SMOC1,SST,SSTR1,SSTR2,EPB41L3,LRRC4,NCDN,STAU1,ELOVL4,SEPT8,STX1A,STXBP1,MLC1,VAMP1,VPS13A,PLCB1,SYPL1,POPDC3,TACR1,DDHD2,ROBO3,CAMTA1,ADGRL3,AGTPBP1,IQCE,ATMIN,TCF4,TCF7L2,ZEB1,TRIM2,USP22,TMEM151B,SLC19A3,ATP13A2,DICER1,SIRT1,CHST8,AP4E1,GPR161,ZNF106,AKTIP,SLC44A1,THRA,ENHO,NACC2,TK2,TLR4,TNFRSF1B,CSMD1,TP53BP2,RBFOX2,SEZ6L,RASD2,WBP2,PRMT8,TRIO,TRPC3,NTSR2,TSC1,TSC2,TST,TTPA,CADM1,UBE3A,UCHL1,FRRS1L,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,WNT7A,LGI4,ZIC1,ZIC2,ZIC3,ELFN1,NDRG4,CELF4,ZNF142,REEP1,ANKS1B,FTSJ1,LRP8,TUBA1A,PCDH15,TMEM163,SLC17A6,PDSS2,EPM2A,PAK5,GJC2,CERS6,RNF170,VANGL2,AAAS,FXR1,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0002272 abnormal nervous system electrophysiology 2.96E-28 2.36E-24 2.62E-25 2.51E-24 170 355 "SYN3,ASIC2,ADCY8,SLC12A5,ADORA1,PTCHD1,PCDH19,SEMA6A,ABCD2,KCNT1,ANK3,CNTNAP1,KCNAB2,ALS2,PRX,MADD,ATP1A2,ATP1A3,ATP2B2,ADGRB3,RGS11,HCN2,BID,MTMR2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA1D,CACNB4,CALB1,CALB2,KALRN,CANX,CD86,ENTPD2,LGI1,CACNA2D2,ASIC3,CHN1,CHRM1,CHRM4,CHRNA4,CHRNB2,STOML1,WHRN,CLOCK,SLC32A1,CNTNAP2,SNAP91,GRIN3A,DNM1,SLC12A6,DPP6,DRD1,EGR3,ELAVL3,EMX2,KCNMB2,GPHN,ERBB2,ETV1,CACNG2,FGF14,FGFR1,GABBR1,GABRB1,GABRG2,GAD1,GAD2,JPH4,NKX6-2,C1QL1,GJB1,KCNMB4,GNG3,MCHR1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIN1,NR3C1,GRM1,GRM5,GRM7,GSN,HLF,IL6ST,LRRTM3,KCNA1,KCNA2,KCNC2,KCNJ10,KCNJ11,KCNJ16,KCNK3,KCNMA1,KCNN3,KCNQ2,KCNQ3,KIT,LAMA2,STMN1,MBP,GIT1,MYO6,MYO7A,NEFH,NEUROD1,NOS1,NRCAM,HCN1,NALCN,PLCL1,JAKMIP1,PLEC,PLP1,PMP2,PMP22,PACSIN1,SLC26A11,SH3TC2,RGS7,GLDN,LRRK2,SCN2A,SCN2B,SCN4B,SCN8A,ARX,SLC1A2,SLC1A3,SLC1A6,SLC6A9,SIRT2,SOX2,SOX10,NFASC,SST,SSTR1,SSTR2,EPB41L3,ERBIN,SEPT8,FGD4,SYN1,ARC,SYN2,TACR1,TCF4,SIK3,TNR,TRPC1,TRPC3,TRPM2,TSC1,UBE3A,UGT8,KCNT2,ELFN1,REEP1,PCDH15,SLC17A7,KCNAB1,EPM2A,JPH3" Mouse Phenotype MP:0002152 abnormal brain morphology 6.68E-28 5.33E-24 5.33E-25 5.10E-24 563 1758 "ABR,ASIC2,ACHE,ARID1A,ADD1,AXIN2,SLC12A5,FZD9,LRFN2,KIDINS220,PCDH19,AGT,NME5,SORCS2,CC2D2A,PLA2G6,SPARCL1,SEMA6A,ABCD2,PCDH10,BBOX1,ALK,MRTFA,AMT,ANK1,ANK3,SEMA7A,CNTNAP1,APAF1,APBB1,APBB2,APC,ALS2,APP,SEMA4G,PRX,SPTBN4,ARHGAP5,CADPS,ASCL1,ASPA,CHRD,NCOA1,NUMB,ASTN1,DYNLL1,TMEM108,ATM,ATP1A2,ATP1A3,ATP2B2,BBS2,RGS9,BCL2L2,FGF17,NRP2,BID,BMP7,CDK5R1,FUBP1,SGCE,CACNA1G,WASF1,CDK5R2,CA8,CACNA1A,CACNA1D,CACNB2,CACNB4,CALB1,KALRN,HAP1,PTBP2,CAMK2A,CANX,BRSK2,CBLN1,KRIT1,RGN,AIFM1,CD81,ARHGEF2,CDH2,DCLK1,ARHGAP33,LGI1,NOG,NUMBL,CACNA2D2,COPB2,GPR37L1,ADGRG1,ASIC3,CHN1,CHN2,CHRM1,CHRNA4,CHRNB2,NDST3,SLIT2,LHX2,DLGAP3,PLAA,PPT2,CLCN3,TPP1,QKI,HECTD1,NIPBL,CNGA3,CNN3,CNR1,CNTFR,CNTN1,GAL3ST1,COX4I1,ZNF521,CP,CLOCK,AKAP12,CRMP1,NCOR1,NCOR2,AATK,CSF1,CSF1R,ATRNL1,CNTNAP2,CST3,PLXNA4,SLITRK5,CTNND1,PYGO1,CYBB,BOC,HDAC4,DGKB,BRINP1,DBN1,DCC,ZEB2,PLPPR4,SRGAP3,KIF19,ARNT2,DLG3,DLG4,DMD,DNM1,OLIG1,NYAP1,MED12,SLC29A4,TRAPPC9,CDON,DNM2,SHANK1,SLC12A6,DPYSL2,DRD1,ABI1,PDCD6IP,DSCAM,DYRK1A,DNM1L,E2F5,E2F6,EBF1,EDIL3,EDNRB,EEF1A2,EFNA2,EFNA3,CELSR3,APH1A,EGFR,ABI2,EML1,EMX2,EN2,OLIG2,ENO2,EPB41L1,EPB41L2,COQ7,EPHB1,ERBB4,ERCC2,APC2,CEND1,EYA1,F3,FABP7,CACNG2,ZIC4,TUBB3,DLC1,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,FOXG1,VTI1B,EVL,DPYSL4,NBEA,TMEM107,SMC2,AK8,STAMBP,ATP2C1,DLL3,TBR1,AP4B1,BRSK1,FYN,MEGF10,GABRA1,GABRA5,CHL1,GABRB3,GAD1,ZMYND11,GALC,B4GALNT1,NKX6-2,IP6K3,GAP43,DISC1,ATP8A2,SRRM4,CPLX2,DNER,GBX2,GDF1,GFAP,FREM1,GHR,PPARGC1A,KIRREL3,GLDC,GLI2,GLRB,GLUL,KDM2B,DCLK2,GNAS,GPT2,PRRC2B,GPM6B,GPR37,CECR2,RAPGEF1,GRIA2,GRIN1,GRIN2C,ATE1,CIT,KIF3A,IL1RAPL1,HLF,SYNPO,HMX1,HPCA,DHX35,HSF2,ATCAY,IGF1,ZIC5,LRRCC1,IGSF1,HES5,IL6ST,INSM1,TUBB2B,LRRTM1,ITGAV,KCNA1,KCNJ10,KCNQ2,KCNQ3,KIF2A,KIF5C,KIT,KLC1,L1CAM,LAMA2,LAMP2,STMN1,LIFR,LIG4,SYTL4,SMAD1,SMAD9,NAT8L,MAP2,MAPT,MBD1,MBP,MDM4,MEF2C,KITLG,PPM1L,AFF1,AFDN,MSI1,BLOC1S2,MTTP,MYCN,MYO5A,MYO9A,NCAM1,NCAM2,NDP,RCOR2,NEK1,NEUROD1,NEUROD2,NF1,NFIA,NFIX,NKX2-2,NODAL,NOS1,SLC11A2,NRCAM,NRDC,HCN1,NTRK2,DDR2,ODF2,OPA1,OPHN1,OXTR,PAH,PAX6,PCDH9,PDE4B,PDGFRA,ENPP2,PDPK1,PDYN,GPR85,ABCB1,NLGN3,SERPINE2,PIK3C2A,PKD1,JAKMIP1,EPN1,PLP1,PLXNB1,ANKRD16,PSAT1,MBOAT7,PACSIN1,FA2H,POU3F2,MED1,PPP3CA,PRKACB,CEP41,MAPK7,MAPK8,MAPK9,HYDIN,PROX1,RELN,LAMA1,PTCH1,PTHLH,PTH1R,PTK2,PEX2,PEX5,CCDC40,ATG16L1,FEZF2,KHDRBS2,CRTAC1,RET,PRRT2,FIGN,RFX4,RGS4,KIF7,RIC8B,SETD5,ROBO1,ROBO2,TMEM100,FBXW7,ZC3H14,RPL38,ACER3,LRRK2,ATAT1,WLS,RXRA,RXRG,SALL1,SATB1,ATXN1,DRAXIN,ATXN2,ATXN7,SCN2A,LRRTM4,SCN8A,SMPD3,SLC30A10,KIF27,SCG5,ITSN1,SH3GL2,ARX,CPEB3,FUZ,AMBRA1,BCAN,SLC1A2,ZNF365,SLC1A3,PREX2,EPN2,SLC6A8,SIRT2,CCDC88A,SHANK2,SLC20A2,TET1,SLIT1,SMARCA4,SMARCC2,CDK5RAP2,IFT122,SNAP25,SNCB,SNCA,MBD5,PALLD,PDZRN3,MYO16,SOX1,SOX2,SOX3,TNIK,SOX10,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,SPTB,KIF1B,NPAS3,NFASC,NCDN,MAPK8IP3,TTBK2,SULF2,STXBP1,MLC1,JMJD6,VPS13A,PLCB1,SYN1,SYN2,COBL,ATP11A,MTCL1,DDHD2,ROBO3,CAMTA1,MLST8,CNTN2,AGTPBP1,MGRN1,ATMIN,TCF4,DMXL2,CUX2,TCF7L2,ZEB1,TRIM2,RPGRIP1L,TCF12,USP22,ARHGEF12,TEK,SIRT1,AP4E1,GPR161,HHIP,THRA,ENHO,TIAM1,TIE1,HEY1,TK2,NR2E1,HEY2,PARD3,TNR,TP53BP2,RBFOX2,CDK20,PRMT8,TRH,TRIO,TRPC3,TSC1,TSC2,TUB,HIRA,HEPACAM,CADM1,UBE3A,AMOT,UCHL1,UGT8,VAV2,TOM1L2,VLDLR,CLIP2,XRCC4,ZBTB14,ZIC1,ZIC2,ZIC3,ZNF24,TRIM9,CRB2,SPHK2,CELF4,REEP1,DPYSL5,SLC30A3,WNK1,MAP3K12,LRP8,RGMA,PRDM8,TUBA1A,SEMA3B,TMEM163,SLC17A6,PDSS2,EPM2A,FZD3,UBE3B,GJC2,CERS6,VANGL2,IFT88,ST8SIA2,SLC4A10" Mouse Phenotype MP:0002064 seizures 6.39E-27 5.10E-23 4.64E-24 4.44E-23 179 390 "SYN3,ACHE,SLC12A5,FZD9,ADORA1,ADORA2A,AMPH,ANK3,KCNAB2,DGKD,NUMB,ATP1A3,HCN2,NRP2,BID,CDK5R1,SYNJ1,SGCE,CACNA1G,C5,BSN,MYRF,BAIAP3,CACNA1A,CACNB4,CAMK2A,P2RX6,AIFM1,SYNGR3,LGI1,NUMBL,CACNA2D2,CHN1,SYNPR,CHRNA4,CHRNB2,CLCN3,TPP1,QKI,CNR1,AKAP5,CREM,CNTNAP2,ARHGAP32,HDAC4,BLOC1S6,PLPPR4,SNAP91,SV2B,SV2A,DNM1,DMTF1,SLC12A6,DRD1,DSCAM,EDIL3,MBNL2,ELAVL3,EML1,OLIG2,SEZ6,APC2,ADGRV1,CACNG2,FGF13,FGF14,FYN,GABBR1,GABRA1,GABRB3,GABRG2,GAD2,GALC,B4GALNT1,CPLX1,GFAP,GFRA2,PPARGC1A,GJB1,KCNMB4,DCLK2,GNAO1,GNG3,TPPP,GRIA2,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,ATE1,GRM5,GRM7,CIT,HLF,ATCAY,ITGAV,KCNA1,KCNA2,KCNA4,KCNC1,KCNC2,KCNJ9,KCNJ10,KCNJ11,KCNK2,KCNQ2,KCNQ3,KIF5A,MAG,MAPT,MBP,DBNL,ADAM22,MYO5A,NEUROD1,NEUROD2,NF1,NOS1,NPY,NTRK2,PAH,PDGFRA,PDYN,SLC10A4,SERPINE2,PLCL1,PLP1,PMP22,PACSIN1,MAPK10,FITM2,PTPRO,PRRT2,KCNIP1,STX1B,ATXN7,SCN2B,SCN8A,SCG5,SH3GL2,SH3GL3,ARX,SLITRK3,ST8SIA1,SLC1A2,SLC1A3,SLC4A3,SLC6A11,NAPB,SNAP25,FAIM2,SOX1,SOX2,SOX10,SST,NCDN,PLCB1,SYN1,SYN2,SYP,CNTN2,TRIM2,TCF12,SZT2,TNFRSF1B,TSC1,TSC2,UBE3A,ZNF24,ELFN1,CELF4,TMEM163,EPM2A,GJC2,NETO1,AP3B2,SLC4A10,GAN" Mouse Phenotype MP:0003313 abnormal locomotor activation 8.69E-24 6.94E-20 5.78E-21 5.53E-20 400 1186 "ADCY5,SLITRK1,ADCYAP1R1,SLC12A5,ADORA2A,PTCHD1,ADRA1D,AGT,SORCS2,CC2D2A,PLA2G6,C1QTNF1,LRRC7,ABCD2,UNC79,ALK,ANK3,CNTNAP1,APAF1,APBA2,APC,ALS2,APP,SPTBN4,ARNTL,ARRB1,ARRB2,ASPA,MARK4,CHRD,CCAR2,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,ADGRB2,RGS9,BCL2L2,HCN2,BCS1L,CDK5R1,CACNA1G,FOXK1,CACNA1A,CACNA1B,DDR1,CACNB4,KALRN,HAP1,CAMK2A,CANX,BRSK2,CCKBR,USP2,AIFM1,CD81,LGI1,DLGAP2,CDO1,CACNA2D2,CFL2,GPR37L1,CHN1,CHRM1,CHRM4,CHRNA4,CHRNB2,PLAA,CLCN3,NRXN1,NRXN2,CLU,TPP1,QKI,CNR1,WHRN,MAGED1,COX4I1,ZNF521,CP,CLOCK,CREM,CRY2,SLC32A1,NCOR1,ABCG1,FEZ1,PDE4DIP,CNTNAP2,APPL1,CTH,CYBB,GPRASP1,HDAC4,DGKB,BRINP1,DBT,DCTN1,SNAP91,SRGAP3,DLG3,DLG4,DMD,OLIG1,SHANK1,SLC12A6,DRD1,RCAN1,USH1C,EFNA2,EFNA3,EIF4G2,COPS4,MRNIP,BSCL2,TMEM35A,EML1,EN2,OLIG2,ENO2,RCAN2,SEZ6,ERBB2,ERBB4,NCALD,PIPOX,F5,FABP7,CACNG2,PRMT5,PPP1R1B,FECH,FGF12,FGF13,FGF14,ACTL6B,FOXG1,CAP2,FOXO3,FLNC,SGIP1,NBEA,PDLIM5,FAM49B,KHDRBS3,BRSK1,DKK3,GAA,GABBR1,GABRA1,GABRA3,GABRA5,GABRB3,GABRG2,GAD2,GALC,JPH4,DISC1,STARD10,CPLX2,GATM,GCNT2,PPARGC1A,GLI2,GLS,GLUL,PCSK1N,GNAL,GNAO1,GNAS,GPT2,GPR22,MCHR1,GPR37,TPPP,GRIA1,GRIA2,GRIA4,PARD3B,GRIN1,GRIN2C,GRIN2D,NR3C1,ATE1,GRM1,GRM2,GRM5,GRM7,KIF3A,GSTM5,MFSD2A,PSIP1,ATG4C,FRMD5,HRH3,VSIG4,ACOT7,SYNPO,HMGCL,HNF4G,HNMT,NEGR1,SMAP1,HTR2A,ATCAY,RBPJ,TUBB2B,LRRTM1,ITPKB,KCNB1,KCNC1,KCNH1,KCNJ3,KCNJ10,KCNJ11,L1CAM,LAMP2,LSAMP,MAG,NAT8L,MAOB,MAP6,MAPT,MBP,ADAM11,MMP16,MN1,MOG,MOV10,GIT1,MYCN,MYH6,MYO5A,MYO6,MYO7A,NDUFA5,NEUROD1,NOS1,NPY,NRCAM,NTRK2,OGG1,OPHN1,OXTR,PCDH9,PDE4B,PDE1B,PDYN,TMOD2,NLGN3,PLCB2,FTO,PLP1,PCDH18,PMP22,MAGEL2,MBOAT7,FA2H,SH3KBP1,PPP3CB,KANSL1,PRKAB2,MAPK3,EPDR1,HYDIN,PROX1,RELN,PTPRG,PEX2,ARID4A,FEZF2,KHDRBS2,RET,PRRT2,RGS4,RGS7,RPE65,ACER3,LRRK2,KCNIP3,RYR1,RYR3,SATB1,ATXN1,ATXN2,ATXN7,SCN3A,SCN8A,ELMOD1,SH3GL2,ARX,CPEB3,FBXO11,CLSTN1,SLC1A2,SLC1A3,SLC4A3,PREX2,WDR47,SLC6A1,SLC6A8,SLC6A9,SIRT2,CCDC88A,SHANK2,SLC12A2,SNAP25,SNCA,KIF13A,ANKFN1,SOX1,SOX2,TNIK,SP4,BEX1,KIF1B,TSPYL2,NPAS3,NFASC,CLSTN2,ITPRID2,SST,SSTR1,SSTR2,LRRC4,NCDN,STAU1,ELOVL4,SEPT8,STX1A,VAMP1,VPS13A,PLCB1,SYPL1,TACR1,DDHD2,ADGRL3,IQCE,ATMIN,TCF4,TCF7L2,ZEB1,TMEM151B,SLC19A3,ATP13A2,DICER1,SIRT1,CHST8,AP4E1,ZNF106,AKTIP,SLC44A1,THRA,ENHO,TK2,TNFRSF1B,CSMD1,RBFOX2,SEZ6L,RASD2,WBP2,PRMT8,TSC1,TSC2,TST,TTPA,UBE3A,UCHL1,FRRS1L,UGT8,TOM1L2,VGF,VIPR2,VLDLR,LMF1,ZIC1,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,ANKS1B,FTSJ1,TUBA1A,PCDH15,TMEM163,SLC17A6,PAK5,GJC2,CERS6,VANGL2,AAAS,IFT88,AP3B2,GAN,JPH3" Mouse Phenotype MP:0001399 hyperactivity 1.04E-23 8.32E-20 6.40E-21 6.12E-20 203 488 "ADCYAP1R1,PTCHD1,AGT,SORCS2,PLA2G6,C1QTNF1,LRRC7,ABCD2,UNC79,APAF1,APP,ASPA,MARK4,CHRD,ATP1A3,B3GALT2,ADGRB2,CDK5R1,CACNA1G,CACNA1B,DDR1,KALRN,CAMK2A,CCKBR,USP2,DLGAP2,CACNA2D2,CHN1,CHRM1,CHRM4,CHRNB2,CLCN3,CNR1,WHRN,COX4I1,ZNF521,CLOCK,CREM,SLC32A1,NCOR1,ABCG1,FEZ1,PDE4DIP,CNTNAP2,APPL1,HDAC4,DGKB,BRINP1,SNAP91,SRGAP3,OLIG1,SLC12A6,DRD1,RCAN1,USH1C,EIF4G2,MRNIP,TMEM35A,EN2,ENO2,RCAN2,ERBB4,NCALD,FABP7,CACNG2,PPP1R1B,FGF12,FGF13,FGF14,ACTL6B,FOXG1,SGIP1,KHDRBS3,DKK3,GABBR1,GABRA1,GABRA3,GABRA5,GABRB3,GABRG2,GALC,DISC1,CPLX2,PPARGC1A,GLUL,GNAL,GNAO1,GNAS,GPR22,MCHR1,TPPP,GRIA1,GRIA2,GRIA4,PARD3B,GRIN1,ATE1,GRM2,GSTM5,MFSD2A,FRMD5,VSIG4,ACOT7,TUBB2B,KCNB1,KCNC1,KCNH1,KCNJ3,L1CAM,LSAMP,MAOB,MAP6,MAPT,ADAM11,MMP16,MOV10,GIT1,MYO5A,MYO6,MYO7A,NEUROD1,NTRK2,OPHN1,OXTR,PCDH9,PDE1B,TMOD2,NLGN3,FTO,SH3KBP1,PPP3CB,KANSL1,MAPK3,PTPRG,FEZF2,PRRT2,RGS4,RPE65,LRRK2,KCNIP3,RYR3,SATB1,ATXN2,ELMOD1,ARX,FBXO11,SLC1A2,WDR47,SLC6A1,SLC6A8,SIRT2,SHANK2,SLC12A2,SNAP25,SNCA,ANKFN1,SOX1,TNIK,SP4,KIF1B,TSPYL2,NPAS3,CLSTN2,ITPRID2,SST,LRRC4,NCDN,STX1A,PLCB1,TACR1,ADGRL3,ATMIN,TCF4,ZEB1,TMEM151B,SIRT1,AP4E1,AKTIP,SLC44A1,THRA,CSMD1,WBP2,PRMT8,TSC1,TST,UCHL1,FRRS1L,TOM1L2,VGF,VLDLR,ZIC2,ELFN1,NDRG4,CELF4,ZNF142,ANKS1B,FTSJ1,TUBA1A,PCDH15,TMEM163,CERS6,IFT88,AP3B2" Mouse Phenotype MP:0002207 abnormal long term potentiation 3.62E-23 2.89E-19 2.06E-20 1.97E-19 121 238 "ASIC1,ADCY8,ADCYAP1R1,ADD2,LRFN2,DOC2A,CNIH2,APP,CHRD,RGS9,KSR1,CDK5R1,WASF1,CACNA1B,CALB2,KALRN,CAMK2A,CAMK2B,SHISA7,SLC24A2,ARHGEF6,CNR1,AKAP5,CRMP1,NCAN,CTNND2,CYBB,DGKB,SIRPA,CNIH3,DLG3,DLG4,DPP6,DRD1,EFNA3,EFNB3,MBNL2,TMEM35A,ERBB4,PPP1R1B,FGF14,BAIAP2,DPYSL4,NBEA,CAMKK2,B3GAT1,FYN,GABBR1,GABRA5,JPH4,DISC1,CPLX2,GFAP,GRIA1,GRIA2,GRIK1,GRIK2,GRIK3,GRIK4,GRIN1,GRM1,GRM5,SYNPO,LRRTM1,ITPKA,KCNJ10,STXBP5,LAMA2,MAPT,MBD1,MEF2C,NCAM1,NELL2,NOS1,NOVA2,NTRK2,IGSF11,OPRL1,PAK3,PDE4B,TMOD2,SERPINE2,PPP1R1A,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK9,PTN,PTPRZ1,RASGRF1,KCNIP3,RYR3,ATXN1,PPP1R9A,BCAN,CLSTN1,SLC1A3,SLC8A2,CCDC88A,SHANK2,SP4,NCDN,STX1A,ARHGEF9,ARC,SYP,WWC1,TCF4,ICAM5,TSC1,TSC2,UBE3A,VLDLR,ELFN1,LRP8,SLC17A7,KCNAB1,TMEM163,NETO1,JPH3" Mouse Phenotype MP:0002572 abnormal emotion/affect behavior 5.36E-23 4.28E-19 2.85E-20 2.73E-19 252 659 "SYN3,SLITRK1,ADCY8,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,PTCHD1,ADRA1B,LRFN2,MTA3,GPR158,PLA2G6,LRRC7,ALK,APBA2,ALS2,APP,ASPA,CHRD,ATP1A1,ATP1A2,ATP1A3,STX16,B3GALT2,ADGRB2,BBS2,RGS9,BCL7A,HCN2,CDK5R1,WASF1,BAIAP3,CACNA1B,CACNA1E,DDR1,CACNB4,KALRN,HAP1,CAMK2A,CAMK2B,CANX,SHISA7,CCKBR,DLGAP2,DLGAP1,CHRNA4,CHRNB2,NDST3,DLGAP3,CLCN3,NRXN2,CLU,QKI,ARHGEF6,CNR1,AKAP5,MAGED1,ZNF521,CLOCK,CREM,CRHBP,NCOR1,CSF1R,CNTNAP2,SLITRK5,ERC2,ARHGAP32,DGKB,BRINP1,SIRPA,KIAA0319,LYPD1,SNAP91,SRGAP3,DLG4,OLIG1,NR1D2,SHANK1,SLC12A6,DRD1,DYRK1A,EFNA2,EFNA3,TMEM35A,HSD17B14,EN2,ENO2,ERBB4,ERCC2,FABP7,KIAA1109,FGF12,FGF13,FGF14,PDLIM5,FYN,GABBR1,GABRA1,CHL1,GABRB3,GABRG2,GAD2,JPH4,DISC1,CPLX2,PCDH17,PPARGC1A,KIRREL3,DHRS4,GLUL,PCSK1N,GNAL,GNAS,ATF7,GPR19,MCHR1,GPR26,TPPP,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,NR3C1,GRM1,GRM2,GRM3,GRM8,FAM19A2,HRH3,SYNPO,HNF4G,HNMT,HSD17B1,HTR2A,HTR5A,IL6R,LRRTM1,KCNC1,KCNC2,KCNH1,KCNJ11,L1CAM,LAMA2,FGFBP3,LSAMP,MAG,NAT8L,MAOB,MAP2,MAP6,MAPT,MOV10,GIT1,MYO7A,NOS1,NPY,HCN1,NTRK2,OPA1,OPHN1,OPRL1,OXTR,P2RX7,PDE4B,PDE1B,PDYN,PENK,ZDHHC8,NLGN3,SERPINI1,JAKMIP1,SH3KBP1,PKIA,PRKCG,PRKCZ,HYDIN,PTCH1,PTPRG,RGS4,RGS7,RORB,ATAT1,KCNIP3,RYR3,ATXN1,SCN8A,ELMOD1,ARX,CPEB3,SLC1A3,SLC6A1,SLC6A8,CCDC88A,SHANK2,EPC1,SNAP25,MBD5,KIF13A,SOX1,SP4,NPAS3,SSTR2,STX1A,ARHGEF9,DNAJC9,SYN1,ARC,SYN2,TAC1,TACR1,TAF6,ADGRL3,ATMIN,WSCD1,TCF4,DMXL2,ZEB1,CRTC1,ATP13A2,SLC44A1,THRA,NR2E1,CSMD1,RASD2,NR2C2,PRMT8,TRPM2,TSN,TSC1,TSC2,UBE3A,UCHL1,TOM1L2,ZIC2,ELFN1,ZNF142,GDPD5,RNF103,TUBA1A,NAV2,SLC17A7,TMEM163,SLC17A6,FZD3,PAK5,CERS6,AAAS,ST8SIA2,SLC4A10,JPH3" Mouse Phenotype MP:0000787 abnormal telencephalon morphology 1.32E-22 1.05E-18 6.58E-20 6.29E-19 310 868 "ACHE,FZD9,LRFN2,AGT,SORCS2,SEMA6A,PCDH10,MRTFA,ANK3,SEMA7A,APAF1,APBB1,APBB2,APC,APP,PRX,SPTBN4,ARHGAP5,CADPS,ASCL1,ASPA,CHRD,NUMB,TMEM108,ATM,ATP1A2,ATP1A3,ATP2B2,BBS2,RGS9,NRP2,BID,CDK5R1,FUBP1,WASF1,CDK5R2,KALRN,HAP1,PTBP2,CAMK2A,CANX,BRSK2,AIFM1,CD81,CDH2,DCLK1,ARHGAP33,LGI1,NOG,NUMBL,COPB2,ADGRG1,CHN1,CHN2,CHRM1,SLIT2,LHX2,DLGAP3,PLAA,PPT2,CLCN3,QKI,NIPBL,CNGA3,CNR1,ZNF521,CLOCK,CRMP1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,SLITRK5,CTNND1,DGKB,BRINP1,DBN1,DCC,DLG3,DLG4,OLIG1,TRAPPC9,CDON,SHANK1,SLC12A6,DPYSL2,DRD1,PDCD6IP,DSCAM,DYRK1A,E2F5,EBF1,EDIL3,EFNA2,EFNA3,CELSR3,APH1A,EGFR,ABI2,EML1,EMX2,OLIG2,ENO2,EPHB1,APC2,FABP7,CACNG2,TUBB3,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,FOXG1,VTI1B,EVL,DPYSL4,SMC2,AK8,STAMBP,TBR1,BRSK1,FYN,GABRA5,CHL1,GABRB3,GAD1,GALC,GAP43,DISC1,SRRM4,CPLX2,GBX2,GFAP,PPARGC1A,KIRREL3,GLI2,DCLK2,GPT2,GPM6B,GRIA2,GRIN1,CIT,KIF3A,SYNPO,HPCA,DHX35,HSF2,IGF1,ZIC5,HES5,IL6ST,TUBB2B,LRRTM1,KCNA1,KCNJ10,KCNQ2,KCNQ3,KIF2A,KIT,L1CAM,LAMA2,LIG4,MAP2,MAPT,MBD1,MBP,MDM4,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,MYO9A,NCAM1,NCAM2,RCOR2,NEK1,NEUROD1,NF1,NFIA,NFIX,NRDC,HCN1,NTRK2,OPA1,OPHN1,PAH,PAX6,PCDH9,ABCB1,PKD1,JAKMIP1,PLP1,PLXNB1,MBOAT7,PACSIN1,POU3F2,MED1,PPP3CA,MAPK8,MAPK9,HYDIN,PROX1,RELN,PTCH1,PEX2,PEX5,FEZF2,CRTAC1,PRRT2,RFX4,RGS4,RIC8B,SETD5,ROBO1,ROBO2,FBXW7,ZC3H14,RPL38,LRRK2,ATAT1,RXRG,SALL1,ATXN1,DRAXIN,LRRTM4,ITSN1,SH3GL2,ARX,CPEB3,FUZ,AMBRA1,BCAN,SLC1A2,SLC6A8,CCDC88A,SLC20A2,TET1,SLIT1,SMARCC2,CDK5RAP2,SNAP25,SNCB,SNCA,SOX1,SOX2,SOX3,SOX10,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,KIF1B,NPAS3,NCDN,MAPK8IP3,MLC1,VPS13A,PLCB1,SYN1,ATP11A,MLST8,CNTN2,AGTPBP1,CUX2,ZEB1,RPGRIP1L,USP22,AP4E1,THRA,HEY1,NR2E1,HEY2,PARD3,TNR,TP53BP2,TRIO,TSC1,TSC2,CADM1,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,ZIC3,TRIM9,REEP1,SLC30A3,MAP3K12,LRP8,PRDM8,TUBA1A,TMEM163,EPM2A,FZD3,UBE3B,CERS6,VANGL2,IFT88,ST8SIA2" Mouse Phenotype MP:0009745 abnormal behavioral response to xenobiotic 1.42E-22 1.14E-18 6.68E-20 6.39E-19 142 303 "ADCY5,SLC12A5,FZD9,ADORA2A,ADRA1D,ADRA1B,SORCS2,UNC79,ALK,AMPH,AQP4,ATP1A1,ATP1A3,MPDZ,HCN2,NRP2,CDK5R1,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CCKBR,P2RX6,AIFM1,CD81,LGI1,CACNA2D2,CHRM4,CHRNA4,CHRNB2,TAOK2,DLGAP3,CLCN3,NIPBL,CNR1,AKAP5,CLOCK,SLITRK5,GPRASP1,ARHGAP32,DGKB,DLG4,NR1D2,SLC12A6,DRD1,EDIL3,MBNL2,EML1,ENO2,SEZ6,EPS8,PPP1R1B,FGF14,PDLIM5,FYN,GABRA1,GABRA2,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD2,DISC1,GFAP,PPARGC1A,GLS,GNAS,PRLHR,MCHR1,GPR26,GRIA1,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,NR3C1,GRM2,GRM5,GRM7,CIT,GSTM5,HLF,KCNA1,KCNA2,KCNC1,KCNC2,KCNK2,KCNQ2,KIT,LAMP2,MAP6,MAPT,MBP,NEUROD2,NOS1,NPY,NTRK2,OPRL1,PDYN,SLC10A4,PENK,SERPINE2,PLCL1,SH3KBP1,PRKCG,MAPK10,PTPRO,PRRT2,RGS4,LRRK2,KCNIP1,RYR1,SCN2B,SCN4B,SCN8A,PPP1R9A,ARX,SLITRK3,SLC1A2,SLC1A3,SLC4A3,SLC6A1,SLC6A9,SLC6A11,FAIM2,NPAS3,NCDN,PLCB1,TACR1,CNTN2,ADGRL3,SZT2,TRPM2,ELFN1,ANKS1B,SLC17A6,SLC4A10" Mouse Phenotype MP:0008540 abnormal cerebral hemisphere morphology 1.08E-20 8.62E-17 4.79E-18 4.58E-17 242 646 "ACHE,FZD9,LRFN2,AGT,SORCS2,SEMA6A,MRTFA,ANK3,APAF1,APBB1,APBB2,APP,SPTBN4,ARHGAP5,CADPS,NUMB,TMEM108,ATM,ATP1A3,ATP2B2,BBS2,NRP2,BID,CDK5R1,FUBP1,WASF1,CDK5R2,KALRN,HAP1,PTBP2,CAMK2A,CANX,BRSK2,AIFM1,CD81,CDH2,DCLK1,ARHGAP33,LGI1,NUMBL,COPB2,ADGRG1,CHN1,CHN2,CHRM1,LHX2,PLAA,PPT2,CLCN3,NIPBL,CNR1,ZNF521,CRMP1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,CTNND1,DGKB,BRINP1,DBN1,DCC,DLG3,DLG4,OLIG1,CDON,SHANK1,SLC12A6,DPYSL2,DRD1,PDCD6IP,DSCAM,DYRK1A,E2F5,EDIL3,EFNA3,CELSR3,EGFR,ABI2,EML1,EMX2,OLIG2,ENO2,EPHB1,APC2,FABP7,CACNG2,TUBB3,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FOXG1,VTI1B,DPYSL4,SMC2,AK8,STAMBP,BRSK1,FYN,GABRA5,CHL1,GABRB3,GAD1,GALC,GAP43,DISC1,SRRM4,CPLX2,GFAP,PPARGC1A,DCLK2,GPT2,GPM6B,GRIA2,GRIN1,CIT,KIF3A,HPCA,HSF2,ZIC5,TUBB2B,LRRTM1,KCNA1,KCNJ10,KCNQ2,KCNQ3,KIF2A,L1CAM,LIG4,MAP2,MAPT,MBD1,MBP,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,NCAM1,RCOR2,NEUROD1,NF1,NFIA,NFIX,NRDC,NTRK2,OPHN1,PAH,PAX6,PCDH9,ABCB1,PLP1,PLXNB1,MBOAT7,PACSIN1,POU3F2,PPP3CA,MAPK8,MAPK9,HYDIN,PROX1,RELN,PEX2,PEX5,FEZF2,PRRT2,RFX4,RGS4,ROBO1,ROBO2,FBXW7,LRRK2,ATAT1,DRAXIN,LRRTM4,ITSN1,SH3GL2,ARX,CPEB3,BCAN,SLC1A2,SLC6A8,CCDC88A,SLC20A2,SMARCC2,CDK5RAP2,SNAP25,SNCA,SOX1,SOX2,SOX3,SOX11,SP2,SP4,MYCBP2,ZNF423,KIF1B,NPAS3,NCDN,MAPK8IP3,MLC1,PLCB1,SYN1,CNTN2,AGTPBP1,CUX2,RPGRIP1L,USP22,AP4E1,THRA,NR2E1,TNR,TP53BP2,TRIO,TSC1,TSC2,CADM1,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,ZIC3,TRIM9,REEP1,SLC30A3,MAP3K12,LRP8,PRDM8,TUBA1A,TMEM163,EPM2A,FZD3,UBE3B,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0008415 abnormal neurite morphology 1.17E-20 9.35E-17 4.92E-18 4.71E-17 187 459 "SLC12A5,LRFN2,KIDINS220,GPR158,SORCS2,PLA2G6,LRRC7,SEMA6A,ABCD2,ANK3,CNTNAP1,ALS2,PRX,SPTBN4,CADPS,NUMB,TMEM108,ATM,BCL2L2,NRP2,CACNA1A,KALRN,HAP1,CAMK2A,CANX,CD86,SEPT7,DCLK1,ARHGAP33,DLGAP2,CACNA2D2,JAM2,SLIT2,PLAA,CLU,QKI,TMEM184B,ARHGEF6,CNTN1,GAL3ST1,CRMP1,AATK,CSF1,VCAN,PLXNA4,SNPH,DBN1,SRGAP3,DLG3,DLG4,GRIN3A,DNM1,OLIG1,NYAP1,SLC12A6,DPYSL2,DRP2,DSCAM,DNM1L,EDIL3,EFNB3,OLIG2,SEZ6,EPHB1,ERBB2,CEND1,NRN1,FGF13,ACTL6B,FOXG1,EVL,POMT1,CAMKK2,GABBR1,CHL1,GABRB3,GALC,IP6K3,GAP43,SRRM4,GJB1,GPM6B,GRIA1,GRIK4,GRM7,HAPLN2,CPT1C,ZIC5,LRRTM3,LRRTM1,KIF2A,KLC1,L1CAM,MAG,MAPT,MBP,PPM1L,MOV10,GIT1,MYO5A,NAP1L1,NCAM1,NEFH,NF1,NFE2L2,NOS1,NRCAM,NRDC,NTRK2,OPHN1,CLDN11,TREM2,PCDH9,PDE4B,ZDHHC8,NLGN3,SEMA5B,PLEC,PLP1,PMP2,PMP22,MBOAT7,FA2H,POU3F2,PRPH,LAMA1,PTPN13,PEX5,SH3TC2,FEZF2,KHDRBS2,RET,ROBO1,ROBO2,GLDN,LRRK2,ATXN1,SH3GL2,CPEB3,NLGN1,CLSTN1,SLC1A3,PREX2,CCDC88A,SHANK2,SLIT1,CPEB4,SNCA,MBD5,MYO16,KIF21B,SOX10,NMNAT2,ZNF423,SPTAN1,NFASC,EPB41L3,ERBIN,STAU1,SEPT8,MLC1,FGD4,MTCL1,AGTPBP1,TRIM2,ZNF106,THRA,TLR4,PRMT8,TRPC3,TSC1,TSC2,HEPACAM,UBE3A,LGI4,ZIC2,ZNF24,ELFN1,REEP1,DPYSL5,SPIRE1,TUBA1A,SLC17A7,TMEM163,SLC17A6,PAK5,GAN" Mouse Phenotype MP:0001405 impaired coordination 1.12E-19 8.90E-16 4.45E-17 4.25E-16 190 477 "ADCY5,PLA2G6,ABCD2,CNTNAP1,GAS7,ALS2,APP,PRX,ASPA,NCOA1,ASTN1,ATM,ATP1A3,ATP2B2,B3GALT2,RGS9,HCN2,BMP7,CDK5R1,MTMR2,SGCE,CACNA1G,WASF1,CA8,CACNA1A,CACNB4,CALB2,KALRN,CAMK2B,CBLN1,CCKBR,AIFM1,CACNA2D2,CLCN3,TPP1,QKI,CNR1,AKAP5,IGDCC3,CP,CSF1R,CTNND2,CYBB,ARHGAP32,SNPH,BRINP1,DCTN1,DLG4,DMD,SHANK1,SLC12A6,DRD1,DTNA,DTNB,EDIL3,SEZ6L2,EEF1A2,EFNB3,CELSR3,MBNL2,ELAVL3,ELAVL4,EN2,SEZ6,ERBB2,APC2,CEND1,CACNG2,FDFT1,FGF14,FGFR1,AP4B1,GAA,GABRA1,GABRB3,GABRG2,GAD1,B4GALNT1,NKX6-2,IP6K3,CPLX2,DNER,PPARGC1A,GJB1,GNAO1,GPR37,GRIA2,GRIN1,GRIN2C,GRM2,GRM7,NXPH3,ACOT7,ITGAV,KCNA2,KCNC1,KCNJ11,KCNMA1,KIF5A,KLC1,L1CAM,MAG,MAPT,MBNL1,MBP,ADAM11,PPM1L,DBNL,MYO5A,NDUFA5,NEUROD2,NF1,NRCAM,NRDC,NTRK3,OPA1,CLDN11,PCDH9,TMOD2,NLGN3,JAKMIP1,PLP1,PMP22,FA2H,MAPK10,SLC26A11,RELN,LAMA1,PTPRG,PTPRZ1,FIGN,RGS4,RORB,ACER3,ATXN1,ATXN2,ATXN7,SCN8A,ITSN1,SH3GL2,ARX,PREX2,SLC6A8,SLC8A3,SIRT2,SHANK2,CPEB4,SNAP25,SNCA,MBD5,SOX10,SP4,KIF1B,NPAS3,NFASC,SSTR2,NCDN,VPS13A,SYT4,TACR1,DDHD2,ROBO3,CAMTA1,AGTPBP1,SYNE1,ZNF106,ENHO,MTMR14,RBFOX2,SEZ6L,RASD2,NR2C2,TSN,TSC1,TSC2,TTPA,UBE3A,UCHL1,UGT8,CLIP2,ELFN1,REEP1,RNF103,PCDH15,SLC17A7,SLC17A6,EPM2A,GJC2,CERS6,JPH3" Mouse Phenotype MP:0003492 abnormal involuntary movement 2.28E-19 1.82E-15 8.66E-17 8.28E-16 324 957 "ACHE,SLITRK1,ADCY8,SLC12A5,ADRA1D,LRFN2,AP2A2,KIAA1324,PLA2G6,LRRC7,ABCD2,MRTFA,ANK1,ANK3,PKP4,CNTNAP1,KCNAB2,APP,MIER1,PRX,MADD,SPTBN4,ARNTL,ASPA,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,ADAM23,BBS2,RGS9,HCN2,BMP7,CDK5R1,SYNJ1,MTMR2,CACNA1I,CACNA1G,BSN,WASF1,MYRF,CDK5R2,CA8,CACNA1A,CACNA1B,CACNA1D,CACNB4,CALB1,KALRN,CANX,CAST,BRSK2,CCK,CCKBR,USP2,AIFM1,CACNA2D2,CFL2,ASIC3,CHN1,CHRNB2,PLAA,PPT2,CLCN3,NRXN1,TPP1,VAX2,QKI,NIPBL,CNGA3,WHRN,GAL3ST1,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,CSF1,TENM4,ARHGEF4,CYBB,ARHGAP32,HDAC4,DCTN1,ZBTB24,SNAP91,DLG2,DLG4,DMD,DNM1,DMTF1,SLC12A6,DRD1,ATN1,DNM1L,USH1C,EDIL3,EDNRA,EEF1A2,EFNA2,EFNA3,EFNB3,EGR3,ELAVL4,EML1,EMX2,EN2,OLIG2,EPS8,ERBB2,ERCC2,NCALD,ADGRV1,CACNG2,ZIC4,FDFT1,PRMT5,KIAA1109,FGF11,FGF14,FGFR1,SUCO,FOXO3,EVL,FLNC,SGIP1,NBEA,POMT1,STAMBP,BRSK1,FYN,GABBR1,GABRA1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,JPH4,SALL3,DISC1,ATP8A2,SRRM4,CPLX2,GATM,PPARGC1A,GJB1,NTNG2,GLI2,GLRB,GNAO1,GNAS,GPM6B,ATF7,GRIA2,GRIA4,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2D,ATE1,GRM1,GRM7,CIT,PSIP1,NXPH3,CPT1C,HSD17B1,ATCAY,ITGAV,KCNA1,KCNA2,KCNC1,KCND2,KCNJ3,KCNJ10,KCNMA1,KIF5A,L1CAM,LAMA2,MAG,MAPT,MBP,PPM1L,MITF,MOG,DBNL,MYO5A,MYO6,MYO7A,NDUFA5,NELL1,NF1,NFIA,NFIX,NHLH1,NOVA1,NPR2,NRCAM,NRDC,NTRK2,NTRK3,OPA1,CLDN11,OXTR,PAX6,PCSK2,PDGFRA,PDYN,TMOD2,ABCB1,NLGN3,TMIE,GPSM2,PLP1,PRIMPOL,PMP2,PMP22,MBOAT7,POU3F4,PRODH,RELN,LAMA1,PTPRG,PEX2,PEX5,SH3TC2,RDX,FIGN,SETD5,RORB,RPE65,EPHA10,ACER3,KCNIP3,RYR1,SATB1,ATXN1,ATXN7,SCN8A,ELMOD1,SH3BP2,FBXO11,PREX2,WDR47,SLC6A1,SLC6A9,SLC8A3,SHANK2,SLC12A2,SLC20A2,SNAP25,SNCA,ANKFN1,SOX1,SOX2,SOX10,SP4,SPP1,ZNF423,BEX1,KIF1B,NPAS3,SMOC1,EPB41L3,LRRC4,ERBIN,STX1A,AJAP1,JMJD6,VAMP1,PLCB1,TACR1,ROBO3,AGTPBP1,IQCE,TCF4,ZEB1,TRIM2,ATP13A2,AP4E1,ZNF106,TK2,TLR4,CSMD1,WBP2,PRMT8,TRIO,NTSR2,TSC1,SSBP2,TTPA,UBE3A,UCHL1,FRRS1L,UGT8,VLDLR,WNT7A,KLC2,LGI4,ZIC1,ZIC2,ZNF24,NDRG4,DPYSL5,SLC30A4,LRP8,RNF103,PCDH15,NAV2,SLC17A7,TMEM163,SLC17A6,PDSS2,EPM2A,FZD3,GJC2,CERS6,AP3B2,JPH3" Mouse Phenotype MP:0009357 abnormal seizure response to inducing agent 4.24E-19 3.38E-15 1.53E-16 1.47E-15 99 195 "SYN3,SLC12A5,FZD9,ADORA1,ADORA2A,AMPH,ATP1A3,HCN2,NRP2,CDK5R1,CACNA1G,BSN,BAIAP3,CACNA1A,P2RX6,AIFM1,LGI1,CACNA2D2,CHRNA4,CHRNB2,CLCN3,TPP1,CNR1,AKAP5,CREM,CNTNAP2,ARHGAP32,HDAC4,DNM1,SLC12A6,EDIL3,MBNL2,EML1,SEZ6,ADGRV1,FGF13,FGF14,FYN,GABBR1,GABRA1,GABRB3,GABRG2,GAD2,B4GALNT1,GFAP,GFRA2,GNAO1,GNG3,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,GRM5,GRM7,CIT,HLF,KCNA1,KCNA2,KCNC2,KCNK2,KCNQ2,KCNQ3,MAPT,MBP,NEUROD2,NOS1,NPY,NTRK2,PAH,PDYN,SLC10A4,SERPINE2,PLCL1,PLP1,MAPK10,PTPRO,PRRT2,KCNIP1,SCN2B,SCN8A,ARX,SLITRK3,ST8SIA1,SLC1A2,SLC1A3,SLC4A3,SLC6A11,FAIM2,PLCB1,SYN1,SYN2,CNTN2,SZT2,TSC2,UBE3A,ELFN1,CELF4,SLC4A10" Mouse Phenotype MP:0000783 abnormal forebrain morphology 4.42E-19 3.53E-15 1.53E-16 1.47E-15 360 1096 "ACHE,ARID1A,FZD9,LRFN2,PCDH19,AGT,SORCS2,SEMA6A,PCDH10,BBOX1,ALK,MRTFA,ANK3,SEMA7A,APAF1,APBB1,APBB2,APC,APP,PRX,SPTBN4,ARHGAP5,CADPS,ASCL1,ASPA,CHRD,NUMB,TMEM108,ATM,ATP1A2,ATP1A3,ATP2B2,BBS2,RGS9,NRP2,BID,CDK5R1,FUBP1,WASF1,CDK5R2,CACNB4,KALRN,HAP1,PTBP2,CAMK2A,CANX,BRSK2,AIFM1,CD81,CDH2,DCLK1,ARHGAP33,LGI1,NOG,NUMBL,CACNA2D2,COPB2,ADGRG1,CHN1,CHN2,CHRM1,CHRNB2,NDST3,SLIT2,LHX2,DLGAP3,PLAA,PPT2,CLCN3,QKI,NIPBL,CNGA3,CNR1,ZNF521,CLOCK,CRMP1,NCOR1,NCOR2,CSF1,CSF1R,CNTNAP2,CST3,PLXNA4,SLITRK5,CTNND1,BOC,DGKB,BRINP1,DBN1,DCC,ARNT2,DLG3,DLG4,DMD,OLIG1,TRAPPC9,CDON,SHANK1,SLC12A6,DPYSL2,DRD1,PDCD6IP,DSCAM,DYRK1A,DNM1L,E2F5,EBF1,EDIL3,EFNA2,EFNA3,CELSR3,APH1A,EGFR,ABI2,EML1,EMX2,OLIG2,ENO2,EPHB1,APC2,EYA1,F3,FABP7,CACNG2,TUBB3,DLC1,ZMYND10,PRMT5,FGF1,FGF13,FGF14,FGFR1,FGFR3,FOXG1,VTI1B,EVL,DPYSL4,NBEA,SMC2,AK8,STAMBP,TBR1,BRSK1,FYN,GABRA5,CHL1,GABRB3,GAD1,ZMYND11,GALC,GAP43,DISC1,SRRM4,CPLX2,GBX2,GDF1,GFAP,GHR,PPARGC1A,KIRREL3,GLI2,DCLK2,GPT2,PRRC2B,GPM6B,GPR37,CECR2,GRIA2,GRIN1,CIT,KIF3A,SYNPO,HPCA,DHX35,HSF2,ATCAY,IGF1,ZIC5,IGSF1,HES5,IL6ST,INSM1,TUBB2B,LRRTM1,KCNA1,KCNJ10,KCNQ2,KCNQ3,KIF2A,KIT,L1CAM,LAMA2,LAMP2,LIG4,SYTL4,SMAD1,MAP2,MAPT,MBD1,MBP,MDM4,PPM1L,AFDN,MSI1,BLOC1S2,MYCN,MYO9A,NCAM1,NCAM2,RCOR2,NEK1,NEUROD1,NF1,NFIA,NFIX,NODAL,NRDC,HCN1,NTRK2,DDR2,OPA1,OPHN1,PAH,PAX6,PCDH9,ENPP2,PDPK1,ABCB1,PIK3C2A,PKD1,JAKMIP1,PLP1,PLXNB1,MBOAT7,PACSIN1,POU3F2,MED1,PPP3CA,MAPK8,MAPK9,HYDIN,PROX1,RELN,PTCH1,PTHLH,PEX2,PEX5,FEZF2,CRTAC1,PRRT2,RFX4,RGS4,RIC8B,SETD5,ROBO1,ROBO2,TMEM100,FBXW7,ZC3H14,RPL38,LRRK2,ATAT1,WLS,RXRG,SALL1,ATXN1,DRAXIN,LRRTM4,SMPD3,SCG5,ITSN1,SH3GL2,ARX,CPEB3,FUZ,AMBRA1,BCAN,SLC1A2,SLC6A8,CCDC88A,SLC20A2,TET1,SLIT1,SMARCC2,CDK5RAP2,SNAP25,SNCB,SNCA,MBD5,SOX1,SOX2,SOX3,SOX10,SOX11,SP2,SP4,NMNAT2,MYCBP2,SPP1,ZNF423,SPTAN1,KIF1B,NPAS3,NCDN,MAPK8IP3,MLC1,VPS13A,PLCB1,SYN1,ATP11A,MLST8,CNTN2,AGTPBP1,DMXL2,CUX2,TCF7L2,ZEB1,RPGRIP1L,USP22,TEK,SIRT1,AP4E1,THRA,TIAM1,TIE1,HEY1,NR2E1,HEY2,PARD3,TNR,TP53BP2,TRH,TRIO,TSC1,TSC2,TUB,HIRA,CADM1,UBE3A,VLDLR,CLIP2,XRCC4,ZIC2,ZIC3,TRIM9,REEP1,SLC30A3,MAP3K12,LRP8,PRDM8,TUBA1A,TMEM163,SLC17A6,EPM2A,FZD3,UBE3B,CERS6,VANGL2,IFT88,ST8SIA2" Mouse Phenotype MP:0002062 abnormal associative learning 5.23E-19 4.17E-15 1.74E-16 1.66E-15 139 316 "ASIC1,ADCY8,ADCYAP1R1,ADD2,PTCHD1,ADRA1B,LRFN2,KCTD16,DOC2A,AMPH,APBB1,KCNAB2,APP,CDC14B,TMEM108,ATP1A3,KSR1,CACNA1B,KALRN,CAMK2A,CAMK2B,SHISA7,CHRNA4,CHRNB2,TAOK2,CNR1,CREM,FEZ1,CTNND2,CYBB,DBN1,LYPD1,SRGAP3,DLG4,DRD1,DYRK1A,EFNA3,ABI2,TMEM35A,ENO2,ERBB4,NRN1,FABP7,PPP1R1B,FGF13,FGF14,NBEA,TBR1,FYN,GABBR1,GABRA1,GABRA2,GABRA5,GABRB1,GABRB3,GAD2,JPH4,GALR1,DISC1,GFAP,GHR,PRLHR,MCHR1,GRIA1,GRIA2,GRIK2,GRIN1,GRIN2C,GRM1,GRM5,GRM7,LRRTM1,KCNMA1,MAP2,MAPT,GIT1,MYO5A,FXYD6,IDNK,HCN1,NTRK2,OPRL1,OXTR,PAK3,PDE4B,PDYN,GPR85,PENK,TMOD2,NLGN3,JAKMIP1,PRKACB,PRKCB,PRKCG,MAPK3,PTPRG,PTPRZ1,RASGRF1,RGS4,CARF,KCNIP3,RYR3,ATXN1,ITSN1,ARX,CPEB3,SLC6A1,SLC6A8,SLC6A9,SLC8A2,CCDC88A,SORCS3,ANKFN1,KIF21B,SP4,NPAS3,STX1A,ARC,SYT4,TACR1,WWC1,CRTC1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,LRP8,RNF103,TMEM163,SLC17A6,EPM2A,FZD3,PAK5,ST8SIA2,JPH3" Mouse Phenotype MP:0002067 abnormal sensory capabilities/reflexes/nociception 9.29E-19 7.41E-15 2.97E-16 2.84E-15 323 961 "ACHE,SLITRK1,ADCY8,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRA1D,LRFN2,AP2A2,KIAA1324,LRRC7,KCNT1,MRTFA,PKP4,APP,PRX,MADD,SPTBN4,ARNTL,ARRB2,ASPA,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,BBS2,RGS9,HCN2,CDK5R1,MTMR2,CACNA1I,BSN,CDK5R2,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB4,CALB1,KALRN,CAST,BRSK2,CCK,CCKBR,USP2,P2RX6,CDH8,CACNA2D2,CFL2,ADGRG1,ASIC3,CHN1,CHRNA4,CHRNB2,PLAA,PPT2,TPP1,NIPBL,CNGA3,HOMER3,CNR1,WHRN,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,CNTNAP2,ARHGEF4,CYBB,ARHGAP32,FRMPD4,HDAC4,GIT2,DCTN1,ZBTB24,SNAP91,DLG2,DLG4,DMTF1,SLC12A6,DRD1,ATN1,DNM1L,USH1C,EDIL3,EDNRA,EDNRB,EFNA2,EFNA3,EFNB3,KMT5B,ELAVL4,EML1,EMX2,EN2,OLIG2,ENO2,GPHN,EPS8,ERBB2,ERCC2,NCALD,ADGRV1,CACNG2,ZIC4,KIAA1109,FGF11,FGF14,FGFR1,SUCO,SEMA6C,FOXO3,EVL,FLNC,FLT1,SGIP1,NBEA,POMT1,STAMBP,BRSK1,FYN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,JPH4,SALL3,DISC1,ATP8A2,SRRM4,CPLX2,GATM,PPARGC1A,NTNG2,GLI2,GLRB,GNAO1,GNAS,ATF7,PRLHR,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2D,ATE1,GRM1,GRM5,GRM7,PSIP1,MAP4K5,NXPH3,CPT1C,HSD17B1,ATCAY,KCNA1,KCNA2,KCNA6,KCND2,KCNJ3,KCNJ10,KCNMA1,L1CAM,LAMA2,MAG,MAPT,MBP,PPM1L,MITF,MOG,DBNL,MYO5A,MYO6,MYO7A,NBL1,NDUFA5,NELL1,NF1,NFIX,NHLH1,NPR2,NRCAM,NRDC,HCN1,NTRK2,NTRK3,OPA1,OPRL1,OXTR,P2RX7,PAH,PAX6,PCDH9,PCSK2,PIRT,PDYN,PENK,TMOD2,NLGN3,SERPINE2,TMIE,RETREG1,GPSM2,PLCB2,PLP1,PMP2,PMP22,MBOAT7,POU3F4,PRKAR1B,PRKCG,PRODH,RELN,LAMA1,PTPRG,PTPRZ1,PEX2,SH3TC2,RDX,FIGN,RGS4,SETD5,ROBO2,RORB,RPE65,EPHA10,ACER3,KCNIP3,RYR1,S100B,SATB1,ATXN1,ATXN7,SCN8A,ELMOD1,SH3BP2,ARX,FBXO11,PREX2,WDR47,SLC6A1,SLC6A9,SLC8A3,SHANK2,SLC12A2,SLC20A2,SNAP25,SNCA,SOX1,SOX2,SOX10,SP4,MYCBP2,SPP1,BEX1,KIF1B,NPAS3,SMOC1,EPB41L3,LRRC4,ERBIN,STX1A,AJAP1,JMJD6,VAMP1,PLCB1,TAC1,TACR1,ROBO3,TCF4,ZEB1,PHF24,ATP13A2,AP4E1,ZNF106,TLR4,NR2E1,CSMD1,WBP2,NR2C2,PRMT8,TRIO,NTSR2,TSC1,SSBP2,UBE3A,UCHL1,FRRS1L,WNT7A,KLC2,LGI4,ZIC1,ZIC2,KCNT2,NDRG4,DPYSL5,SLC30A4,RNF103,PCDH15,NAV2,SLC17A7,TMEM163,SLC17A6,PDSS2,EPM2A,FZD3,CERS6,RNF170,JPH3" Mouse Phenotype MP:0002910 abnormal excitatory postsynaptic currents 4.64E-18 3.70E-14 1.42E-15 1.36E-14 79 144 "SYN3,DSCAML1,ADORA1,LRFN2,GPR158,APBA2,MADD,CADPS,TMEM108,RGS9,CACNA1A,KALRN,CAMK2A,CBLN1,SHISA7,CCKBR,CHRM1,CLCN3,NRXN1,NRXN2,LYPD1,PLPPR4,SNAP91,DLG2,DLG3,DNM1,SEZ6L2,CACNG7,SEZ6,EPS8,CACNG3,CACNG2,FGF13,NBEA,CSPG5,GABBR1,GABRB3,GAD2,CPLX2,CPLX1,DNER,PCLO,GRIA2,GRIK4,GRIK5,GRIN1,GRIN2C,GRM1,GRM7,LRRTM3,LRRTM1,KCNJ10,IGSF11,NLGN3,SERPINE2,PACSIN1,PRKCG,STX1B,PPP1R9A,SH3GL2,SH3GL3,NLGN1,CLSTN1,SLC1A3,RAB3GAP1,CCDC88A,NAPB,STX1A,PLCB1,SYT1,RIMBP2,SEZ6L,TRPC3,ELFN1,ANKS1B,SLC17A7,SLC17A6,NETO2,NETO1" Mouse Phenotype MP:0001469 abnormal contextual conditioning behavior 2.77E-17 2.21E-13 8.18E-15 7.82E-14 85 164 "ADCY8,ADCYAP1R1,ADD2,PTCHD1,LRFN2,KCTD16,AMPH,KCNAB2,APP,CDC14B,TMEM108,ATP1A3,KSR1,KALRN,CAMK2A,CAMK2B,SHISA7,CREM,FEZ1,CTNND2,DLG4,DRD1,DYRK1A,EFNA3,ABI2,TMEM35A,ENO2,ERBB4,NRN1,FABP7,FGF14,NBEA,GABRA2,GABRA5,GABRB3,GAD2,DISC1,GRIA2,GRIK2,GRIN1,GRIN2C,GRM1,GRM5,GRM7,LRRTM1,MAP2,MAPT,GIT1,NTRK2,OXTR,GPR85,TMOD2,NLGN3,PRKCB,PRKCG,PTPRZ1,RASGRF1,CARF,KCNIP3,RYR3,ITSN1,ARX,CPEB3,SLC6A1,SLC6A8,SLC8A2,CCDC88A,SP4,STX1A,ARC,SYT4,WWC1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,LRP8,RNF103,TMEM163,SLC17A6,ST8SIA2" Mouse Phenotype MP:0002065 abnormal fear/anxiety-related behavior 1.08E-16 8.58E-13 3.07E-14 2.93E-13 158 395 "SLITRK1,ADCY8,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADRA1B,LRFN2,GPR158,LRRC7,ALK,APBA2,ALS2,APP,ASPA,ATP1A1,ATP1A2,ATP1A3,B3GALT2,RGS9,CDK5R1,WASF1,BAIAP3,CACNA1B,CACNA1E,DDR1,CACNB4,KALRN,CAMK2A,CAMK2B,SHISA7,CCKBR,CHRNA4,CHRNB2,NDST3,DLGAP3,NRXN2,CNR1,AKAP5,ZNF521,CREM,CRHBP,CSF1R,SLITRK5,BRINP1,KIAA0319,LYPD1,SNAP91,SRGAP3,DLG4,NR1D2,SHANK1,DRD1,EFNA2,EFNA3,TMEM35A,ENO2,ERBB4,FABP7,KIAA1109,FGF13,FGF14,FYN,GABBR1,GABRA1,CHL1,GABRG2,GAD2,DISC1,CPLX2,PPARGC1A,GLUL,PCSK1N,ATF7,GPR19,MCHR1,GPR26,TPPP,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,NR3C1,GRM2,GRM3,GRM8,FAM19A2,HRH3,SYNPO,HTR2A,LRRTM1,KCNC2,KCNJ11,L1CAM,FGFBP3,LSAMP,MAOB,MAP2,MAP6,MAPT,MOV10,GIT1,MYO7A,NOS1,NPY,HCN1,NTRK2,OPHN1,PDE4B,PDYN,PENK,NLGN3,SERPINI1,JAKMIP1,PRKCG,PRKCZ,HYDIN,PTCH1,PTPRG,ATAT1,KCNIP3,RYR3,SCN8A,ARX,CPEB3,SLC1A3,SHANK2,SNAP25,KIF13A,SP4,NPAS3,SSTR2,STX1A,ARHGEF9,DNAJC9,ARC,TAC1,TACR1,ADGRL3,ATMIN,TCF4,CRTC1,THRA,NR2E1,CSMD1,RASD2,NR2C2,TRPM2,TSC1,TOM1L2,ELFN1,RNF103,TUBA1A,SLC17A7,TMEM163,PAK5,SLC4A10" Mouse Phenotype MP:0002915 abnormal synaptic depression 1.24E-16 9.92E-13 3.42E-14 3.27E-13 72 131 "SYN3,ADCY8,ADORA1,LRRC7,ADGRB3,RGS9,CDK5R1,SYNJ1,BSN,WASF1,CAMK2A,CAMK2B,CBLN1,CHRM1,CHRM4,NRXN1,NRXN2,SLC24A2,ARHGEF6,CNR1,PICK1,AKAP5,CALY,SV2B,SV2A,EFNB3,CSPG5,DISC1,GFAP,PCDH17,C1QL1,PCLO,GRIA1,GRIA2,GRIN1,NR3C1,GRM1,GRM2,LRRTM3,KCNMA1,LAMA2,MAPT,MYO5A,NCAM1,NOS1,PDE4B,NLGN3,PACSIN1,PRKACB,PRKAR1B,RAB3A,RYR3,SCN4B,SH3GL2,SH3GL3,CPEB3,SLC8A2,SHANK2,SORCS3,NCDN,STX1A,ARHGEF9,SYN1,SYN2,SYT1,WWC1,UCHL1,VGF,ELFN1,DPYSL5,ANKS1B,SLC17A6" Mouse Phenotype MP:0001961 abnormal reflex 4.41E-16 3.52E-12 1.17E-13 1.12E-12 267 787 "ACHE,SLITRK1,ADCY8,SLC12A5,ADRA1D,LRFN2,AP2A2,KIAA1324,LRRC7,MRTFA,PKP4,APP,PRX,MADD,SPTBN4,ARNTL,ASPA,ATP1A2,ATP1A3,ATP2A2,ATP2B2,B3GALT2,KIF1A,BBS2,RGS9,CDK5R1,MTMR2,CACNA1I,BSN,CDK5R2,CACNA1A,CACNA1B,CACNA1D,CACNB4,CALB1,KALRN,CAST,BRSK2,CCK,CCKBR,USP2,CACNA2D2,CFL2,ASIC3,CHN1,CHRNB2,PLAA,PPT2,NIPBL,CNGA3,WHRN,COX4I1,PREPL,AKAP12,HAPLN1,CRY2,ARHGEF4,CYBB,ARHGAP32,HDAC4,DCTN1,ZBTB24,SNAP91,DLG2,DLG4,DMTF1,SLC12A6,DRD1,ATN1,DNM1L,USH1C,EDIL3,EDNRA,EFNA2,EFNA3,EFNB3,ELAVL4,EML1,EMX2,EN2,OLIG2,EPS8,ERBB2,ERCC2,NCALD,ADGRV1,CACNG2,ZIC4,KIAA1109,FGF11,FGF14,FGFR1,SUCO,FOXO3,EVL,FLNC,SGIP1,NBEA,POMT1,STAMBP,BRSK1,FYN,GABBR1,GABRA1,GABRA3,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,JPH4,SALL3,DISC1,ATP8A2,SRRM4,CPLX2,GATM,PPARGC1A,NTNG2,GLI2,GLRB,GNAO1,GNAS,ATF7,GRIA2,GRIA4,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2D,ATE1,GRM1,GRM7,PSIP1,NXPH3,CPT1C,HSD17B1,ATCAY,KCNA1,KCNA2,KCND2,KCNJ3,KCNJ10,KCNMA1,L1CAM,LAMA2,MAG,MAPT,MBP,PPM1L,MITF,MOG,DBNL,MYO5A,MYO6,MYO7A,NDUFA5,NELL1,NF1,NFIX,NHLH1,NPR2,NRCAM,NRDC,NTRK2,NTRK3,OPA1,OXTR,PAX6,PCSK2,PDYN,TMOD2,NLGN3,TMIE,GPSM2,PLP1,PMP2,PMP22,MBOAT7,POU3F4,PRODH,RELN,LAMA1,PTPRG,PEX2,SH3TC2,RDX,FIGN,SETD5,RORB,RPE65,EPHA10,ACER3,KCNIP3,RYR1,SATB1,ATXN1,ATXN7,SCN8A,ELMOD1,SH3BP2,FBXO11,PREX2,WDR47,SLC6A1,SLC6A9,SLC8A3,SHANK2,SLC12A2,SLC20A2,SNAP25,SNCA,SOX1,SOX2,SOX10,SP4,SPP1,BEX1,KIF1B,NPAS3,SMOC1,EPB41L3,LRRC4,ERBIN,STX1A,AJAP1,JMJD6,VAMP1,PLCB1,TACR1,ROBO3,TCF4,ZEB1,ATP13A2,AP4E1,ZNF106,TLR4,CSMD1,WBP2,PRMT8,TRIO,NTSR2,TSC1,SSBP2,UBE3A,UCHL1,FRRS1L,WNT7A,KLC2,LGI4,ZIC1,ZIC2,NDRG4,DPYSL5,SLC30A4,RNF103,PCDH15,NAV2,SLC17A7,TMEM163,SLC17A6,PDSS2,EPM2A,FZD3,CERS6,JPH3" Mouse Phenotype MP:0001463 abnormal spatial learning 4.68E-16 3.73E-12 1.20E-13 1.15E-12 111 248 "ASIC1,ADD2,SLC12A5,FZD9,ADRA1B,LRFN2,AMPH,APBB1,KCNAB2,APP,CHRD,NCOA1,ATP1A2,ATP1A3,CDK5R1,WASF1,CACNA1B,CAMK2A,DLGAP2,CHRNB2,SLC24A2,ARHGEF6,AKAP5,CLOCK,CRMP1,CTNND2,CYBB,DLG3,DLG4,SHANK1,DRD1,EDIL3,EML1,EN2,ENO2,SEZ6,NRN1,FGF13,FGF14,BAIAP2,NBEA,CAMKK2,B3GAT1,FYN,GABRA5,DISC1,CPLX2,GRIA2,GRIN1,GRM1,GRM5,NXPH3,HRH3,SYNPO,CPT1C,L1CAM,MAPT,MBD1,MBP,ADAM11,GIT1,NCAM1,NF1,NOS1,NRCAM,HCN1,NTRK2,OPHN1,OPRL1,PDE1B,TMOD2,NLGN3,FA2H,PRKCG,PTPRZ1,RASGRF1,KCNIP3,RYR3,ATXN1,ITSN1,ARX,SLC6A8,SLC6A9,SLC8A2,CCDC88A,SHANK2,TET1,SORCS3,SNAP25,KIF21B,SP4,CLSTN2,NCDN,ARHGEF9,PLCB1,ARC,DDHD2,WWC1,TCF4,ATP13A2,NR2E1,TSC1,TSC2,UBE3A,VGF,ZIC2,NDRG4,LRP8,KCNAB1,TMEM163,SLC17A6" Mouse Phenotype MP:0001468 abnormal temporal memory 6.05E-16 4.83E-12 1.51E-13 1.44E-12 93 194 "ADCY8,ADCYAP1R1,ADD2,PTCHD1,LRFN2,KCTD16,AMPH,KCNAB2,APP,CDC14B,TMEM108,ATP1A3,KSR1,KALRN,CAMK2A,CAMK2B,SHISA7,CREM,NCOR1,FEZ1,CTNND2,SRGAP3,DLG4,DRD1,DYRK1A,EFNA3,ABI2,TMEM35A,ENO2,ERBB4,NRN1,FABP7,FGF14,NBEA,GABRA2,GABRA5,GABRB3,GAD2,JPH4,DISC1,GRIA2,GRIK2,GRIN1,GRIN2C,GRM1,GRM5,GRM7,LRRTM1,MAP2,MAPT,GIT1,NTRK2,OXTR,PCDH9,GPR85,TMOD2,NLGN3,PRKCB,PRKCG,PTPRZ1,RASGRF1,CARF,KCNIP3,RYR3,ITSN1,ARX,CPEB3,SLC6A1,SLC6A8,SLC8A2,CCDC88A,TET1,SP4,STX1A,ARC,SYN2,SYT4,WWC1,TSC1,TSC2,UBE3A,VGF,VLDLR,CLIP2,ZIC2,SPIRE1,LRP8,RNF103,SLC17A7,TMEM163,SLC17A6,ST8SIA2,JPH3" Mouse Phenotype MP:0000947 convulsive seizures 7.98E-16 6.37E-12 1.93E-13 1.85E-12 87 177 "SYN3,SLC12A5,AMPH,ANK3,ATP1A3,HCN2,NRP2,BID,SYNJ1,SGCE,C5,BSN,CACNA1A,CACNB4,LGI1,CACNA2D2,CHN1,CHRNA4,CLCN3,TPP1,QKI,HDAC4,BLOC1S6,PLPPR4,SNAP91,DNM1,DRD1,MBNL2,EML1,ADGRV1,FYN,GABBR1,GABRA1,GAD2,B4GALNT1,PPARGC1A,GJB1,DCLK2,GNG3,TPPP,GRIA2,GRIK4,GRIN1,ATE1,GRM5,GRM7,CIT,HLF,ITGAV,KCNA1,KCNA2,KCNC1,KCNC2,KCNJ10,KCNJ11,KCNQ2,MAG,MBP,DBNL,ADAM22,MYO5A,NEUROD1,NEUROD2,PAH,PLP1,PMP22,PACSIN1,FITM2,PRRT2,ATXN7,SCN8A,SCG5,ARX,ST8SIA1,SLC1A2,SNAP25,SST,PLCB1,SYN1,SYN2,SZT2,UBE3A,ZNF24,CELF4,EPM2A,GJC2,AP3B2" Mouse Phenotype MP:0000801 abnormal temporal lobe morphology 4.10E-15 3.28E-11 9.64E-13 9.21E-12 148 375 "FZD9,LRFN2,AGT,SEMA6A,MRTFA,ANK3,APBB1,APBB2,SPTBN4,CADPS,NUMB,TMEM108,ATP1A3,ATP2B2,BBS2,NRP2,BID,CDK5R1,CDK5R2,KALRN,PTBP2,CAMK2A,BRSK2,CD81,DCLK1,ARHGAP33,LGI1,NUMBL,CHN2,CHRM1,LHX2,CLCN3,ZNF521,CRMP1,CSF1,CST3,PLXNA4,CTNND1,DGKB,BRINP1,DBN1,DLG4,SHANK1,SLC12A6,DRD1,PDCD6IP,DSCAM,DYRK1A,EDIL3,EFNA3,ABI2,EMX2,ENO2,APC2,FABP7,CACNG2,FGF13,FGF14,FOXG1,DPYSL4,AK8,STAMBP,BRSK1,FYN,GABRA5,CHL1,GABRB3,DISC1,CPLX2,GFAP,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HPCA,HSF2,ZIC5,LRRTM1,KCNA1,KCNQ2,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NCAM1,NEUROD1,NF1,NFIA,NFIX,PAX6,ABCB1,PLP1,MBOAT7,PACSIN1,PPP3CA,PROX1,RELN,FEZF2,RGS4,LRRK2,ATAT1,LRRTM4,ITSN1,SH3GL2,ARX,CPEB3,BCAN,SLC1A2,SLC6A8,CCDC88A,CDK5RAP2,SNAP25,SNCA,SOX1,SOX2,SOX11,SP2,SP4,MYCBP2,ZNF423,KIF1B,NPAS3,NCDN,MAPK8IP3,PLCB1,SYN1,AGTPBP1,THRA,NR2E1,TNR,TRIO,TSC1,TSC2,CADM1,VLDLR,ZIC3,SLC30A3,LRP8,TUBA1A,EPM2A,UBE3B,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0003312 abnormal locomotor coordination 5.93E-15 4.73E-11 1.35E-12 1.29E-11 236 687 "ABR,ACHE,SLC12A5,PTCHD1,PLA2G6,ABCD2,AMPD2,AMPD3,ANK3,PPFIA2,CNTNAP1,APBA2,APP,PRX,SPTBN4,ARNTL,ASPA,NUMB,ATM,ATP1A3,ATP2B2,KIF1A,ADAM23,BCL2L2,HCN2,FGF17,BID,PROM1,SYNJ1,MTMR2,BSN,MYRF,CA8,CACNA1A,CACNA1B,CACNB4,CALB1,CAMK2B,CANX,CAST,CBLN1,RGN,AIFM1,NEURL1,CACNA2D2,CHN1,PLAA,PPT2,CLCN3,TPP1,QKI,CNTN1,WHRN,GAL3ST1,CP,CSF1R,DAPK1,DCC,DCTN1,BLOC1S6,DMD,DNM1,SLC12A6,DRD1,ATN1,DSCAM,E2F5,E2F6,USH1C,EDIL3,ATL1,CACNG7,EFNB3,EGR3,OLIG2,SEZ6,ERBB2,ERCC2,APC2,ETV1,CEND1,F3,CACNG3,CACNG2,ZIC4,FDFT1,FGF12,FGF14,FGFR1,FGFR3,SUCO,GAA,GABBR1,GABRB3,GABRG2,GAD1,GALC,B4GALNT1,IP6K3,ATP8A2,CPLX2,CPLX1,GJB1,HPGDS,GLI2,GLRB,GNAS,GPM6B,GPR22,GRIA4,GRIN1,GRM1,GRM7,GRM8,CIT,MFSD2A,HAS2,ATCAY,ZIC5,ITGA7,ITGAV,KCNA1,KCNA2,KCNB1,KCNC1,KCNJ10,KCNMA1,L1CAM,LAMA2,LIG4,LSAMP,MAG,MAPT,MBP,MEF2C,PPM1L,AFF1,GIT1,DBNL,MSI1,ADAM22,MSRA,MYO5A,MYO6,MYO7A,MYO9A,NEUROD1,NEUROD2,NF1,NFIX,NRCAM,NTRK3,OPA1,PAH,PDGFRA,TMIE,PLP1,ANKRD16,PMP22,MBOAT7,POU3F4,HYDIN,RELN,LAMA1,PTCH1,PTHLH,PEX2,PEX5,OXR1,FIGN,ROBO2,RORB,GLDN,STX1B,ATXN1,ATXN7,SCN8A,ELMOD1,ARX,PREX2,SLC6A1,SLC6A8,SLC12A2,NAPB,SNAP25,SNCA,ANKFN1,SOX2,SOX10,ZNF423,NPAS3,NFASC,SMOC1,EPB41L3,STXBP1,MLC1,VAMP1,VPS13A,DDHD2,ROBO3,CAMTA1,AGTPBP1,TRIM2,USP22,ATP13A2,ZNF106,THRA,NACC2,TK2,TP53BP2,RBFOX2,SEZ6L,PRMT8,TRIO,TRPC3,NTSR2,TSC1,TSC2,TTPA,UBE3A,UCHL1,FRRS1L,UGT8,VLDLR,WNT7A,ZIC1,NDRG4,REEP1,LRP8,PCDH15,PDSS2,EPM2A,GJC2,RNF170,FXR1,GAN" Mouse Phenotype MP:0004166 abnormal limbic system morphology 1.05E-14 8.36E-11 2.32E-12 2.22E-11 159 416 "FZD9,LRFN2,AGT,SEMA6A,ALK,MRTFA,ANK3,APAF1,APBB1,APBB2,CADPS,NUMB,TMEM108,ATP1A2,ATP1A3,BBS2,NRP2,BID,CDK5R1,WASF1,CDK5R2,KALRN,HAP1,PTBP2,CAMK2A,BRSK2,CD81,DCLK1,LGI1,NUMBL,CHN2,LHX2,CLCN3,ZNF521,CLOCK,CRMP1,CSF1,CST3,PLXNA4,CTNND1,DGKB,BRINP1,DBN1,ARNT2,DLG4,SHANK1,SLC12A6,DRD1,PDCD6IP,DSCAM,DYRK1A,EDIL3,EFNA3,ABI2,EMX2,ENO2,APC2,FABP7,CACNG2,FGF13,FGF14,FOXG1,DPYSL4,AK8,STAMBP,TBR1,BRSK1,FYN,GABRA5,CHL1,GABRB3,DISC1,CPLX2,GFAP,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HPCA,HSF2,ZIC5,LRRTM1,KCNA1,KCNQ2,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NCAM1,NEUROD1,NF1,NFIA,NFIX,NTRK2,PAX6,ABCB1,PLP1,MBOAT7,PACSIN1,POU3F2,PPP3CA,PROX1,RELN,FEZF2,RGS4,LRRK2,ATAT1,LRRTM4,ITSN1,SH3GL2,ARX,CPEB3,BCAN,SLC1A2,SLC6A8,CCDC88A,TET1,CDK5RAP2,SNAP25,SNCA,SOX1,SOX2,SOX3,SOX11,SP2,SP4,MYCBP2,ZNF423,KIF1B,NPAS3,NCDN,MAPK8IP3,PLCB1,SYN1,AGTPBP1,DMXL2,THRA,NR2E1,TNR,TRIO,TSC1,TSC2,TUB,CADM1,VLDLR,ZIC2,ZIC3,SLC30A3,LRP8,TUBA1A,EPM2A,UBE3B,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0001473 reduced long term potentiation 2.80E-14 2.24E-10 6.05E-12 5.78E-11 77 156 "ADCY8,ADCYAP1R1,ADD2,DOC2A,CNIH2,APP,RGS9,KSR1,CDK5R1,CACNA1B,CALB2,KALRN,CAMK2A,CAMK2B,SHISA7,SLC24A2,ARHGEF6,AKAP5,CYBB,DGKB,SIRPA,CNIH3,EFNA3,EFNB3,MBNL2,TMEM35A,PPP1R1B,FGF14,DPYSL4,B3GAT1,FYN,GABBR1,JPH4,DISC1,CPLX2,GRIA1,GRIK2,GRIK3,GRIK4,GRIN1,GRM1,GRM5,SYNPO,LRRTM1,MAPT,NCAM1,NOS1,NTRK2,IGSF11,PAK3,SERPINE2,PPP1R1A,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK9,RASGRF1,ATXN1,PPP1R9A,SLC1A3,CCDC88A,SHANK2,SP4,NCDN,STX1A,ARC,SYP,WWC1,TSC1,UBE3A,VLDLR,ELFN1,LRP8,SLC17A7,NETO1,JPH3" Mouse Phenotype MP:0000807 abnormal hippocampus morphology 6.92E-14 5.52E-10 1.45E-11 1.39E-10 143 369 "FZD9,LRFN2,AGT,SEMA6A,MRTFA,ANK3,APBB1,APBB2,CADPS,NUMB,TMEM108,ATP1A3,BBS2,NRP2,BID,CDK5R1,CDK5R2,KALRN,PTBP2,CAMK2A,BRSK2,CD81,DCLK1,LGI1,NUMBL,CHN2,LHX2,CLCN3,ZNF521,CRMP1,CSF1,CST3,PLXNA4,CTNND1,DGKB,BRINP1,DBN1,DLG4,SHANK1,SLC12A6,DRD1,PDCD6IP,DSCAM,DYRK1A,EDIL3,EFNA3,ABI2,EMX2,ENO2,APC2,FABP7,CACNG2,FGF13,FGF14,FOXG1,DPYSL4,AK8,STAMBP,BRSK1,FYN,GABRA5,CHL1,GABRB3,CPLX2,GFAP,PPARGC1A,DCLK2,GPT2,GRIA2,CIT,HPCA,HSF2,ZIC5,LRRTM1,KCNA1,KCNQ2,KCNQ3,KIF2A,L1CAM,MAP2,MAPT,MBD1,AFDN,NCAM1,NEUROD1,NF1,NFIA,NFIX,PAX6,ABCB1,PLP1,MBOAT7,PACSIN1,PPP3CA,PROX1,RELN,FEZF2,RGS4,LRRK2,ATAT1,LRRTM4,ITSN1,SH3GL2,ARX,CPEB3,BCAN,SLC1A2,SLC6A8,CCDC88A,CDK5RAP2,SNAP25,SNCA,SOX1,SOX2,SOX11,SP2,SP4,MYCBP2,ZNF423,KIF1B,NPAS3,NCDN,MAPK8IP3,PLCB1,SYN1,AGTPBP1,THRA,NR2E1,TNR,TRIO,TSC1,TSC2,CADM1,VLDLR,ZIC3,SLC30A3,LRP8,TUBA1A,EPM2A,UBE3B,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0000950 abnormal seizure response to pharmacological agent 7.48E-14 5.97E-10 1.53E-11 1.46E-10 70 138 "SLC12A5,FZD9,AMPH,ATP1A3,HCN2,NRP2,CDK5R1,CACNA1G,BSN,BAIAP3,CACNA1A,P2RX6,AIFM1,LGI1,CACNA2D2,CHRNA4,CLCN3,CNR1,AKAP5,ARHGAP32,SLC12A6,EDIL3,MBNL2,EML1,SEZ6,FGF14,GABRA1,GABRB3,GABRG2,GAD2,GFAP,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,GRM5,GRM7,CIT,KCNA1,KCNA2,KCNC2,KCNK2,KCNQ2,MAPT,MBP,NEUROD2,NPY,PDYN,SLC10A4,SERPINE2,PLCL1,MAPK10,PTPRO,PRRT2,KCNIP1,SCN2B,SCN8A,ARX,SLITRK3,SLC1A2,SLC1A3,SLC4A3,SLC6A11,FAIM2,PLCB1,CNTN2,SZT2,ELFN1,SLC4A10" Mouse Phenotype MP:0001362 abnormal anxiety-related response 1.13E-13 9.06E-10 2.26E-11 2.17E-10 138 354 "SLITRK1,ADCY8,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,GPR158,LRRC7,ALK,APBA2,ALS2,APP,ASPA,ATP1A1,ATP1A2,ATP1A3,B3GALT2,RGS9,WASF1,BAIAP3,CACNA1B,CACNA1E,DDR1,KALRN,CAMK2A,CAMK2B,CCKBR,CHRNA4,CHRNB2,NDST3,DLGAP3,NRXN2,CNR1,AKAP5,ZNF521,CREM,CRHBP,CSF1R,SLITRK5,BRINP1,KIAA0319,LYPD1,SNAP91,DLG4,NR1D2,SHANK1,DRD1,EFNA2,EFNA3,TMEM35A,ENO2,ERBB4,FABP7,KIAA1109,FGF13,FGF14,CHL1,GABRG2,GAD2,DISC1,CPLX2,PPARGC1A,PCSK1N,ATF7,GPR19,MCHR1,GPR26,TPPP,GRIA1,GRIA2,GRIA4,GRIN1,NR3C1,GRM2,GRM3,GRM8,FAM19A2,HRH3,SYNPO,HTR2A,LRRTM1,KCNC2,KCNJ11,L1CAM,FGFBP3,LSAMP,MAOB,MAP6,MAPT,MOV10,GIT1,MYO7A,NOS1,NPY,HCN1,NTRK2,OPHN1,PDE4B,PDYN,PENK,NLGN3,SERPINI1,JAKMIP1,PRKCG,PRKCZ,ATAT1,KCNIP3,SCN8A,ARX,CPEB3,SLC1A3,SHANK2,SNAP25,KIF13A,NPAS3,SSTR2,STX1A,ARHGEF9,DNAJC9,TAC1,TACR1,ADGRL3,ATMIN,TCF4,CRTC1,THRA,NR2E1,CSMD1,RASD2,NR2C2,TRPM2,TSC1,ELFN1,RNF103,TUBA1A,SLC17A7,TMEM163,SLC4A10" Mouse Phenotype MP:0001393 ataxia 3.41E-13 2.72E-09 6.63E-11 6.34E-10 132 338 "PLA2G6,ABCD2,ANK3,CNTNAP1,APBA2,APP,SPTBN4,ASPA,NUMB,ATM,ATP1A3,ATP2B2,KIF1A,ADAM23,BCL2L2,HCN2,BID,PROM1,SYNJ1,BSN,MYRF,CA8,CACNA1A,CACNB4,CALB1,CAMK2B,CANX,CBLN1,AIFM1,CACNA2D2,PLAA,PPT2,TPP1,QKI,CNTN1,GAL3ST1,CSF1R,DCC,BLOC1S6,DNM1,SLC12A6,E2F5,E2F6,CACNG7,EFNB3,EGR3,OLIG2,ERBB2,ERCC2,ETV1,F3,CACNG3,CACNG2,ZIC4,FDFT1,FGF12,FGF14,GALC,B4GALNT1,ATP8A2,CPLX1,GJB1,HPGDS,GNAS,GPM6B,GRIA4,GRIN1,GRM1,CIT,MFSD2A,ATCAY,ITGAV,KCNA1,KCNA2,KCNC1,KCNJ10,KCNMA1,LAMA2,LIG4,MAPT,MBP,AFF1,MSI1,ADAM22,MYO5A,NEUROD1,NEUROD2,NF1,NFIX,NRCAM,OPA1,PLP1,ANKRD16,PMP22,HYDIN,RELN,PTCH1,PEX5,OXR1,GLDN,STX1B,ATXN1,ATXN7,SCN8A,SLC6A1,SLC12A2,NAPB,SNAP25,ZNF423,NFASC,EPB41L3,STXBP1,MLC1,ROBO3,CAMTA1,AGTPBP1,TRIM2,THRA,RBFOX2,TRIO,TSC1,TSC2,TTPA,UCHL1,UGT8,VLDLR,ZIC1,LRP8,PCDH15,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0003861 abnormal nervous system development 8.34E-13 6.66E-09 1.58E-10 1.51E-09 379 1269 "ABR,SYN3,ARID1A,ADAR,ADD1,AXIN2,BRAP,FZD9,KIDINS220,PCDH19,NME5,CC2D2A,BBOX1,MRTFA,AMT,SEMA7A,EP400,APAF1,APBB1,APBB2,APC,EPB41L5,APP,PRX,ASCL1,CHRD,NUMB,ASTN1,DYNLL1,ATP2B2,BARD1,BCL2L2,NRP2,BMP7,BMPR1B,CDK5R1,WASF1,CDK5R2,CACNA1A,CACNB2,KALRN,HAP1,PTBP2,BRSK2,ISPD,KRIT1,CDH2,DCLK1,LGI1,NOG,NUMBL,CACNA2D2,GPR37L1,ADGRG1,CHN1,CHN2,CHRM1,NDST3,SLIT2,LHX2,NRXN1,NRXN2,NGEF,VAX2,QKI,HECTD1,CNN3,CNR1,CNTN1,COX4I1,RTTN,ZNF521,NCOR1,NCOR2,CSF1,TENM4,CSF1R,PLXNA4,PYGO1,BOC,ARHGAP32,HDAC4,KIF26A,KIAA0586,BRINP1,DCC,DCTN1,ZEB2,FBXL5,MED24,SRGAP3,KIF19,DLG3,OLIG1,MED12,CDON,DNM2,SHANK1,DPH1,ABI1,PDCD6IP,DSCAM,DTNA,DTNB,DYRK1A,DNM1L,E2F5,EBF1,EDIL3,WDPCP,EDN3,EFNA2,EFNA3,RBM12,EFNB3,CELSR3,APH1A,EGFR,ELAVL4,EML1,EMX2,EN2,OLIG2,COQ7,EPHB1,GPHN,ERBB2,ERBB4,ETV1,CEND1,NRN1,F3,CACNG2,ZIC4,TUBB3,DLC1,ZMYND10,FDFT1,PRMT5,SEC24B,ACTL6B,FGFR1,FOXG1,VTI1B,EVL,TMEM107,SMC2,AK8,ATP2C1,DLL3,FUT9,TBR1,BRSK1,GALC,NKX6-2,IP6K3,NCKAP1,GAP43,SRRM4,DNER,GBX2,GDF1,GFAP,GFRA1,GLDC,GLI2,KDM2B,GPT2,GPM6A,CECR2,RAPGEF1,GRIA2,KIF3A,RNF165,SYNPO,HMX1,ZDHHC15,DHX35,ZIC5,RBPJ,LRRCC1,HES5,IL6ST,INSM1,TUBB2B,ITGA7,ITGAV,KCNA1,KIF2A,KIT,L1CAM,LAMA2,LIG4,LMO2,SMAD1,SMAD9,MAP2,MAPT,MBD1,MDFI,MDM4,MEIS2,KITLG,MITF,AFDN,MSI1,BLOC1S2,MTTP,MYCN,MYO9A,NAP1L2,NCAM1,NEFH,NEK1,NEUROD1,NF1,NFIA,NFIX,NKX2-2,NODAL,NOS1,NRCAM,HCN1,NTRK2,ODF2,OPA1,OPHN1,PAX6,PCSK5,PDE4B,PDGFRA,ENPP2,PDPK1,NLGN3,SERPINE2,PIK3C2A,PKD1,EPN1,PLP1,PLXNB1,PSAT1,PRRX1,MBOAT7,POU3F2,MED1,PRKACB,CEP41,PKN2,MAPK7,MAPK8,MAPK9,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,PEX5,TMEM231,RAD17,CCDC40,RAD51D,FAT4,FEZF2,KHDRBS2,CRTAC1,RET,REV3L,FIGN,RFX4,RGS4,KIF7,ROBO1,ROBO2,TMEM100,FBXW7,RPL38,LRRK2,WLS,RXRA,SALL1,LRRTM4,SCN8A,KIF27,ARX,FUZ,AMBRA1,NLGN1,DZIP1,SLC1A3,EPN2,DHX30,CCDC88A,TET1,SLIT1,CPEB4,SMARCA4,SMARCC2,CDK5RAP2,IFT122,PALLD,SOX1,SOX2,TNIK,SOX10,SOX11,SP2,NMNAT2,CLUAP1,MYCBP2,UNC5B,ZNF423,SPTAN1,NPAS3,MESP1,SS18,MAPK8IP3,STAU1,TTBK2,JMJD6,SYN1,SYN2,COBL,ATP11A,ROBO3,MLST8,UNC5D,CNTN2,ATMIN,TCF4,CUX2,ZEB1,RPGRIP1L,TCF12,USP22,TEK,DICER1,SIRT1,GPR161,HHIP,THRA,TIAM1,TIE1,HEY1,TLR4,NR2E1,HEY2,PARD3,TP53BP2,RBFOX2,CDK20,TRIO,TSC1,TSC2,HIRA,VAV2,TOM1L2,VLDLR,PORCN,ZBTB14,ZIC1,ZIC2,ZIC3,TRIM9,CRB2,SPHK2,MAP3K12,LRP8,RGMA,GDPD5,PRDM8,ADAMTS9,TMEM163,PDSS2,FZD3,RTN4,VANGL2,IFT88,ST8SIA2" Mouse Phenotype MP:0012349 increased susceptibility to induction of seizure by inducing agent 8.49E-13 6.78E-09 1.58E-10 1.51E-09 59 112 "SLC12A5,FZD9,AMPH,ATP1A3,HCN2,NRP2,CDK5R1,BSN,BAIAP3,CACNA1A,LGI1,CACNA2D2,CHRNA4,CHRNB2,CNR1,ARHGAP32,SLC12A6,EDIL3,MBNL2,EML1,FGF14,GABRA1,GABRB3,GABRG2,GFAP,GRIK2,GRIK4,GRIK5,GRIN1,GRM5,GRM7,CIT,KCNA1,KCNA2,KCNC2,KCNK2,KCNQ2,MBP,NEUROD2,NPY,PDYN,SLC10A4,SERPINE2,PLCL1,PTPRO,PRRT2,KCNIP1,SCN2B,ARX,SLITRK3,SLC1A2,SLC1A3,SLC4A3,FAIM2,PLCB1,CNTN2,SZT2,ELFN1,CELF4" Mouse Phenotype MP:0004811 abnormal neuron physiology 4.48E-12 3.57E-08 8.12E-10 7.77E-09 225 684 "NDRG2,UNC5A,KIDINS220,SLC24A4,PCDH19,SORCS2,KCNT1,MRTFA,AMPH,APAF1,GAS7,ALS2,SEMA4G,CASK,CADPS,ASCL1,NUMB,ASTN1,ATM,ATP1A3,ATP2B2,KIF1A,HCN2,NRP2,WASF1,CA8,CACNA1D,CALB1,KALRN,HAP1,CAMK2A,CAST,INA,AIFM1,ARHGEF2,CDH2,DLGAP2,NUMBL,CACNA2D2,COPB2,GPR37L1,ADGRG1,CHRM4,PLAA,PPT2,CNR1,WHRN,MAGED1,CREM,CRMP1,NCOR2,AATK,CSNK1E,CNTNAP2,RIMS2,CX3CR1,SNPH,HDAC4,KIF26A,MAML1,DAPK1,DNAJC6,DCTN1,SNAP91,DNM1,CDON,DRD1,DNM1L,USH1C,EDIL3,CELSR3,PLXNC1,ELAVL4,EML1,EMX2,EN2,OLIG2,ENO2,APC2,CEND1,ADGRV1,FKTN,PRMT5,FGF13,FGFR1,MAD2L2,FOXG1,VTI1B,TBR1,GABBR1,GABRG2,GAD1,GAD2,GAP43,CPLX2,CPLX1,GFAP,GFRA1,GLI2,KDM2B,GPR37,GRIA2,GRIA4,GRIN1,NR3C1,GRM2,GRM3,GRM7,CIT,GSTM5,HPCA,IGF1,INSM1,TUBB2B,KCNJ16,KCNMA1,KCNQ2,KCNQ3,KIF2A,KIF5A,KLC1,LAMA2,LIG4,MAOB,MAPT,MBP,MEF2C,MOG,DBNL,BLOC1S2,MDGA1,MYCN,MYO7A,NAP1L1,NCAM2,RCOR2,NEFH,NEUROD1,NF1,NOS1,NOVA1,NTRK2,OGG1,PAX6,PIRT,PDPK1,PLCB2,PLP1,PLXNB1,MBOAT7,PACSIN1,POU3F2,MED1,KANSL1,MAPK9,MAPK10,RELN,PTCH1,STRC,OXR1,RET,RFX3,RIC8B,ROBO1,FBXW7,STX1B,SCN8A,TNFRSF19,ITSN1,PPP1R9A,SH3GL2,SH3GL3,ARX,CPEB3,SLC6A8,SLC6A9,SLC8A2,CCDC88A,NAPB,TET1,SMARCC2,CDK5RAP2,SNCA,SOX1,SOX2,SOX10,SOX11,SP2,SPP1,ZNF423,KIF1B,MAPK8IP3,STX1A,SYN1,SYT1,TACR1,TAL1,UNC5D,TCF4,CUX2,THRA,TLR4,NR2E1,TNFRSF1B,TP53BP2,RBFOX2,IL34,NR2C2,TRIO,TSC1,FLRT2,VLDLR,XRCC4,TRIM9,DPYSL5,MAP3K12,LRP8,GDPD5,TUBA1A,PCDH15,PDSS2,EPM2A,ST8SIA2,SLC4A10,GAN" Mouse Phenotype MP:0002906 increased susceptibility to pharmacologically induced seizures 5.07E-12 4.04E-08 8.99E-10 8.59E-09 57 110 "SLC12A5,FZD9,AMPH,ATP1A3,HCN2,NRP2,CDK5R1,BSN,BAIAP3,CACNA1A,LGI1,CACNA2D2,CHRNA4,CNR1,ARHGAP32,SLC12A6,EDIL3,MBNL2,EML1,FGF14,GABRA1,GABRB3,GABRG2,GFAP,GRIK2,GRIK4,GRIK5,GRIN1,GRM5,GRM7,CIT,KCNA1,KCNA2,KCNC2,KCNK2,KCNQ2,MBP,NEUROD2,NPY,PDYN,SLC10A4,SERPINE2,PLCL1,PTPRO,PRRT2,KCNIP1,SCN2B,ARX,SLITRK3,SLC1A2,SLC1A3,SLC4A3,FAIM2,PLCB1,CNTN2,SZT2,ELFN1" Mouse Phenotype MP:0009538 abnormal synapse morphology 8.79E-12 7.02E-08 1.53E-09 1.46E-08 89 208 "SLC12A5,LRFN2,GAS7,ALS2,APP,MADD,CADPS,KIF1A,BSN,CACNA1A,CACNB4,KALRN,CAMK2A,CBLN1,DLGAP2,CACNA2D2,PLAA,CLCN3,TMEM184B,ARHGEF6,CLIP3,ERC2,RIMS2,DGKB,SIRPA,DNAJC6,DCTN1,SNAP91,DLG3,DMD,DNM1,DTNA,EDNRB,EEF1A2,MBNL2,OLIG2,GPHN,ERBB2,NRN1,CACNG2,NBEA,POMT1,GABRA1,GABRG2,NKX6-2,PCDH17,GPT2,PCLO,GRIK4,GRM7,IGSF21,LRRTM1,MAP6,MAPT,MBNL1,AFDN,NRCAM,NTRK2,ZDHHC8,NLGN3,PACSIN1,SH3TC2,RET,PRRT2,STX1B,SCN8A,SH3GL2,SH3GL3,SLITRK3,NLGN1,SLC6A8,SHANK2,NAPB,CPEB4,KIF21B,LHFPL4,MYCBP2,KIF1B,NFASC,CLSTN2,STX1A,SYNE2,SYN2,SYNE1,TNR,UCHL1,SLC30A3,SLC17A7,SLC17A6" Mouse Phenotype MP:0000847 abnormal metencephalon morphology 2.78E-11 2.22E-07 4.71E-09 4.51E-08 174 506 "ABR,SLC12A5,SORCS2,SPARCL1,SEMA6A,ABCD2,ANK1,ANK3,CNTNAP1,ALS2,APP,SEMA4G,SPTBN4,CADPS,ASCL1,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,BID,CDK5R1,FUBP1,SGCE,CACNA1G,CDK5R2,CA8,CACNA1A,CACNA1D,CALB1,CANX,CBLN1,AIFM1,ARHGEF2,DCLK1,LGI1,CACNA2D2,GPR37L1,ADGRG1,SLIT2,PLAA,PPT2,TPP1,QKI,NIPBL,CNTFR,CNTN1,ZNF521,CP,AKAP12,DCC,DNM1,OLIG1,SLC12A6,DSCAM,DNM1L,E2F6,EBF1,EDIL3,EEF1A2,EGFR,EN2,ENO2,EPB41L1,EPB41L2,ERBB4,ERCC2,APC2,CEND1,ZIC4,PRMT5,FGF13,FGFR1,AP4B1,MEGF10,GABRA1,GABRB3,GALC,B4GALNT1,NKX6-2,IP6K3,DISC1,DNER,GBX2,PPARGC1A,GLI2,GLRB,GNAS,GRIN2C,CIT,IL1RAPL1,IGF1,TUBB2B,KIF2A,L1CAM,MAP2,MBP,MDM4,AFF1,MYCN,MYO5A,NCAM1,NEUROD1,NEUROD2,NFIA,NRCAM,NTRK2,OPA1,PAX6,PDYN,SERPINE2,JAKMIP1,PLP1,PLXNB1,ANKRD16,FA2H,POU3F2,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,RET,FIGN,ROBO2,FBXW7,ACER3,WLS,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,SHANK2,TNIK,SOX11,NMNAT2,ZNF423,NPAS3,NFASC,STXBP1,MLC1,MTCL1,ROBO3,CAMTA1,AGTPBP1,TRIM2,RPGRIP1L,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UBE3A,UGT8,VLDLR,XRCC4,ZIC1,ZIC3,DPYSL5,LRP8,PDSS2,EPM2A,GJC2,VANGL2,ST8SIA2" Mouse Phenotype MP:0000849 abnormal cerebellum morphology 3.53E-11 2.82E-07 5.87E-09 5.61E-08 164 471 "ABR,SLC12A5,SORCS2,SPARCL1,SEMA6A,ABCD2,ANK1,ANK3,CNTNAP1,ALS2,APP,SEMA4G,SPTBN4,CADPS,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,BID,CDK5R1,FUBP1,SGCE,CACNA1G,CDK5R2,CA8,CACNA1A,CALB1,CANX,CBLN1,AIFM1,ARHGEF2,DCLK1,LGI1,CACNA2D2,GPR37L1,ADGRG1,SLIT2,PLAA,PPT2,TPP1,QKI,NIPBL,CNTN1,ZNF521,CP,AKAP12,DNM1,OLIG1,SLC12A6,DSCAM,DNM1L,E2F6,EDIL3,EEF1A2,EGFR,EN2,ENO2,EPB41L1,EPB41L2,ERBB4,ERCC2,APC2,CEND1,ZIC4,PRMT5,FGF13,FGFR1,AP4B1,MEGF10,GABRA1,GABRB3,GALC,B4GALNT1,IP6K3,DISC1,DNER,GBX2,PPARGC1A,GLI2,GLRB,GNAS,GRIN2C,CIT,IL1RAPL1,IGF1,TUBB2B,KIF2A,L1CAM,MAP2,MBP,MDM4,AFF1,MYCN,MYO5A,NCAM1,NEUROD1,NEUROD2,NFIA,NRCAM,NTRK2,OPA1,PAX6,PDYN,SERPINE2,JAKMIP1,PLP1,PLXNB1,ANKRD16,FA2H,POU3F2,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,FIGN,ROBO2,FBXW7,ACER3,WLS,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,SHANK2,TNIK,SOX11,ZNF423,NPAS3,NFASC,STXBP1,MLC1,MTCL1,CAMTA1,AGTPBP1,TRIM2,RPGRIP1L,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UBE3A,UGT8,VLDLR,XRCC4,ZIC1,ZIC3,DPYSL5,LRP8,PDSS2,EPM2A,GJC2,ST8SIA2" Mouse Phenotype MP:0002199 abnormal brain commissure morphology 4.02E-11 3.21E-07 6.55E-09 6.27E-08 79 181 "MRTFA,APBB1,APBB2,APP,ARHGAP5,NUMB,NRP2,CDK5R1,WASF1,PTBP2,CANX,CD81,DCLK1,NUMBL,PLAA,NIPBL,CSF1R,CNTNAP2,PLXNA4,DCC,SLC12A6,DSCAM,EBF1,EDIL3,CELSR3,ABI2,EMX2,OLIG2,EPHB1,TUBB3,FGFR1,FOXG1,VTI1B,TBR1,FYN,GALC,SRRM4,GFAP,GPM6B,KIF3A,TUBB2B,MAP2,MBP,PPM1L,MSI1,NFIA,NFIX,PAX6,PLP1,PLXNB1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,ARX,SOX1,SOX2,SOX3,MYCBP2,ZNF423,KIF1B,NPAS3,MAPK8IP3,MLC1,ROBO3,CNTN2,RPGRIP1L,AP4E1,NR2E1,CLIP2,ZIC2,TRIM9,MAP3K12,PRDM8,SEMA3B,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0000778 abnormal nervous system tract morphology 5.22E-11 4.17E-07 8.33E-09 7.97E-08 90 217 "MRTFA,APBB1,APBB2,ALS2,APP,ARHGAP5,NUMB,NRP2,CDK5R1,WASF1,PTBP2,CANX,ISPD,CD81,CDH2,DCLK1,NUMBL,CHN1,SLIT2,PLAA,NIPBL,CSF1R,CNTNAP2,PLXNA4,DCC,SLC12A6,DSCAM,EBF1,EDIL3,EFNB3,CELSR3,ABI2,EMX2,OLIG2,EPHB1,TUBB3,FGF14,FGFR1,FOXG1,VTI1B,TBR1,FYN,GALC,SRRM4,GFAP,GPM6B,KIF3A,TUBB2B,L1CAM,MAP2,MBP,PPM1L,AFDN,MSI1,NFIA,NFIX,PAX6,PLP1,PLXNB1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,ARX,SLIT1,SOX1,SOX2,SOX3,NMNAT2,MYCBP2,ZNF423,KIF1B,NPAS3,MAPK8IP3,MLC1,ROBO3,CNTN2,RPGRIP1L,AP4E1,NR2E1,CLIP2,ZIC2,TRIM9,MAP3K12,PRDM8,SEMA3B,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0002945 abnormal inhibitory postsynaptic currents 5.68E-11 4.53E-07 8.89E-09 8.50E-08 47 87 "SYN3,SEMA6A,APBA2,BAIAP3,CACNA1A,CACNA1B,CHRM1,CHRNA4,NRXN2,CNR1,SLC32A1,ERC2,SNAP91,SV2A,DNM1,FGF13,NBEA,CSPG5,GABBR1,GABRA1,GABRA4,GABRA5,GABRG2,GAD1,GAD2,CPLX2,CPLX1,DCLK2,GPR37,GRIK1,GRIK2,IL1RAPL1,KCNA1,KCNA2,NOVA2,NLGN3,PACSIN1,PRRT2,STX1B,NLGN1,SLC6A1,SLC6A9,STX1A,ARHGEF9,SYN1,SYT1,SYT5" Mouse Phenotype MP:0002912 abnormal excitatory postsynaptic potential 6.92E-11 5.53E-07 1.06E-08 1.02E-07 54 107 "ASIC1,ADORA1,CDK5R1,WASF1,CACNA1A,CACNA1B,CAMK2A,CHRM1,DLGAP3,CLCN3,CNR1,AKAP5,SIRPA,PLPPR4,SNAP91,DLG2,EFNA3,MBNL2,EGR3,OLIG2,SEZ6,ERBB2,FYN,GAD1,JPH4,GALR1,GFAP,GRIA1,GRIA2,GRIA4,GRIK2,GRM2,GRM5,STXBP5,MAPT,AFDN,NTRK2,OPHN1,NLGN3,SERPINE2,MAPK9,RASGRF1,ATXN1,LRRTM4,CLSTN1,SHANK2,TNIK,SST,STX1A,ARHGEF9,SYN1,SYN2,SLC17A7,JPH3" Mouse Phenotype MP:0000780 abnormal corpus callosum morphology 8.48E-11 6.77E-07 1.28E-08 1.22E-07 68 149 "MRTFA,APBB1,APBB2,APP,ARHGAP5,NUMB,CDK5R1,WASF1,PTBP2,CANX,CD81,DCLK1,NUMBL,PLAA,NIPBL,CSF1R,CNTNAP2,DCC,SLC12A6,DSCAM,EDIL3,ABI2,EMX2,OLIG2,EPHB1,TUBB3,FGFR1,FOXG1,VTI1B,FYN,GALC,SRRM4,GFAP,GPM6B,KIF3A,TUBB2B,MAP2,MBP,PPM1L,MSI1,NFIA,NFIX,PLP1,PLXNB1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,ARX,SOX2,SOX3,MYCBP2,ZNF423,NPAS3,MAPK8IP3,MLC1,CNTN2,RPGRIP1L,AP4E1,CLIP2,ZIC2,TRIM9,MAP3K12,PRDM8,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0005404 abnormal axon morphology 1.16E-10 9.25E-07 1.71E-08 1.64E-07 91 223 "KIDINS220,PLA2G6,ABCD2,ANK3,CNTNAP1,ALS2,PRX,SPTBN4,CADPS,CACNA1A,CANX,CD86,SEPT7,DCLK1,CACNA2D2,QKI,TMEM184B,GAL3ST1,AATK,VCAN,SNPH,DLG3,OLIG1,SLC12A6,DRP2,EFNB3,OLIG2,EPHB1,ERBB2,FGF13,POMT1,CAMKK2,GABBR1,CHL1,GALC,GAP43,GJB1,GPM6B,GRM7,HAPLN2,ZIC5,KIF2A,KLC1,MAG,MAPT,MBP,PPM1L,NCAM1,NEFH,NFE2L2,NRCAM,NRDC,NTRK2,CLDN11,NLGN3,PLEC,PLP1,PMP2,PMP22,FA2H,POU3F2,PRPH,PTPN13,PEX5,SH3TC2,FEZF2,KHDRBS2,GLDN,LRRK2,SH3GL2,NLGN1,SNCA,SOX10,SPTAN1,NFASC,EPB41L3,ERBIN,SEPT8,MLC1,FGD4,MTCL1,TRIM2,ZNF106,TLR4,HEPACAM,LGI4,ZNF24,REEP1,SLC17A7,TMEM163,GAN" Mouse Phenotype MP:0008026 abnormal brain white matter morphology 1.20E-10 9.58E-07 1.74E-08 1.67E-07 94 233 "PLA2G6,MRTFA,APBB1,APBB2,APP,ARHGAP5,ASPA,NUMB,NRP2,CDK5R1,WASF1,PTBP2,CANX,CD81,DCLK1,NUMBL,PLAA,PPT2,QKI,NIPBL,CSF1R,CNTNAP2,PLXNA4,DBN1,DCC,SRGAP3,SLC12A6,DSCAM,DNM1L,EBF1,EDIL3,CELSR3,ABI2,EMX2,OLIG2,EPHB1,TUBB3,FGFR1,FOXG1,VTI1B,EVL,TBR1,FYN,GALC,SRRM4,GFAP,GPM6B,KIF3A,DHX35,ATCAY,TUBB2B,KLC1,MAP2,MBP,PPM1L,MSI1,NFIA,NFIX,PAX6,PLP1,PLXNB1,PEX2,PEX5,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,ARX,SOX1,SOX2,SOX3,NMNAT2,MYCBP2,ZNF423,KIF1B,NPAS3,MAPK8IP3,MLC1,ROBO3,CNTN2,RPGRIP1L,AP4E1,NR2E1,CLIP2,ZIC2,TRIM9,MAP3K12,PRDM8,SEMA3B,FZD3,GJC2,VANGL2,ST8SIA2" Mouse Phenotype MP:0004994 abnormal brain wave pattern 1.31E-10 1.04E-06 1.86E-08 1.78E-07 42 75 "SYN3,PCDH19,ANK3,BID,BSN,CACNA1A,LGI1,CACNA2D2,CHRM4,CHRNA4,CNTNAP2,SNAP91,DNM1,DRD1,ELAVL3,CACNG2,GABRG2,GAD1,GNG3,GRIK4,GRIN1,HLF,KCNA1,KCNA2,KCNC2,KCNQ2,GIT1,NEUROD1,NOS1,NALCN,ARX,SLC1A2,SSTR1,SSTR2,SYN1,SYN2,SIK3,TRPM2,TSC1,UBE3A,ELFN1,EPM2A" Mouse Phenotype MP:0003107 abnormal response to novelty 1.40E-10 1.12E-06 1.96E-08 1.88E-07 114 301 "ADORA2A,ADRA1B,PLA2G6,LRRC7,APBA2,ALS2,APP,CHRD,ATP1A1,ATP1A3,STX16,BCL7A,WASF1,BAIAP3,CANX,CHRNA4,CHRNB2,CLCN3,NRXN2,QKI,ARHGEF6,CNR1,MAGED1,CLOCK,NCOR1,CNTNAP2,ERC2,ARHGAP32,DGKB,BRINP1,SIRPA,SNAP91,SRGAP3,OLIG1,SLC12A6,DYRK1A,EFNA2,EFNA3,ENO2,ERCC2,FGF12,FGF14,GABBR1,CHL1,GABRB3,JPH4,DISC1,CPLX2,GNAL,GNAS,GRIA1,GRIA2,GRIA4,GRIN1,GRM1,GRM8,HSD17B1,HTR5A,LRRTM1,KCNC1,KCNJ11,L1CAM,LSAMP,NAT8L,MAOB,NPY,NTRK2,OPA1,OPHN1,OPRL1,PDE4B,PDE1B,ZDHHC8,SERPINI1,SH3KBP1,PKIA,RGS7,RORB,ATXN1,ARX,SLC6A1,SLC6A8,CCDC88A,SHANK2,MBD5,SP4,NPAS3,SSTR2,STX1A,ARHGEF9,TAF6,WSCD1,TCF4,DMXL2,CRTC1,ATP13A2,SLC44A1,NR2E1,PRMT8,TSC1,TSC2,ELFN1,ZNF142,GDPD5,TUBA1A,NAV2,TMEM163,SLC17A6,PAK5,CERS6,AAAS,ST8SIA2,SLC4A10,JPH3" Mouse Phenotype MP:0004097 abnormal cerebellar cortex morphology 1.51E-10 1.20E-06 2.07E-08 1.98E-07 134 371 "ABR,SLC12A5,SORCS2,SPARCL1,SEMA6A,ABCD2,ANK1,ANK3,CNTNAP1,ALS2,APP,SEMA4G,CADPS,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,BID,CDK5R1,FUBP1,SGCE,CACNA1G,CDK5R2,CA8,CACNA1A,CALB1,CBLN1,AIFM1,DCLK1,LGI1,CACNA2D2,GPR37L1,ADGRG1,SLIT2,PLAA,PPT2,TPP1,QKI,CNTN1,CP,AKAP12,DNM1,DSCAM,DNM1L,EDIL3,EEF1A2,EGFR,EN2,ENO2,ERBB4,ERCC2,APC2,CEND1,ZIC4,FGF13,FGFR1,AP4B1,GABRA1,GABRB3,B4GALNT1,IP6K3,DNER,GBX2,GLI2,GLRB,GNAS,GRIN2C,CIT,IL1RAPL1,IGF1,L1CAM,MAP2,MDM4,AFF1,MYCN,MYO5A,NEUROD1,NFIA,NRCAM,NTRK2,PAX6,PDYN,SERPINE2,PLP1,PLXNB1,ANKRD16,FA2H,POU3F2,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,FIGN,ROBO2,FBXW7,ACER3,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,SHANK2,TNIK,ZNF423,NPAS3,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UGT8,VLDLR,XRCC4,ZIC1,DPYSL5,LRP8,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0008219 abnormal dorsal telencephalic commissure morphology 2.51E-10 2.00E-06 3.39E-08 3.24E-07 68 152 "MRTFA,APBB1,APBB2,APP,ARHGAP5,NUMB,CDK5R1,WASF1,PTBP2,CANX,CD81,DCLK1,NUMBL,PLAA,NIPBL,CSF1R,CNTNAP2,DCC,SLC12A6,DSCAM,EDIL3,ABI2,EMX2,OLIG2,EPHB1,TUBB3,FGFR1,FOXG1,VTI1B,FYN,GALC,SRRM4,GFAP,GPM6B,KIF3A,TUBB2B,MAP2,MBP,PPM1L,MSI1,NFIA,NFIX,PLP1,PLXNB1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,ARX,SOX2,SOX3,MYCBP2,ZNF423,NPAS3,MAPK8IP3,MLC1,CNTN2,RPGRIP1L,AP4E1,CLIP2,ZIC2,TRIM9,MAP3K12,PRDM8,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0001363 increased anxiety-related response 2.82E-10 2.25E-06 3.75E-08 3.59E-07 87 213 "SLITRK1,SLC12A5,ADORA1,ADORA2A,LRRC7,ALK,APBA2,ALS2,APP,ATP1A1,ATP1A2,ATP1A3,RGS9,BAIAP3,CACNA1E,CCKBR,CHRNA4,DLGAP3,NRXN2,CNR1,CREM,CRHBP,CSF1R,SLITRK5,LYPD1,DLG4,NR1D2,SHANK1,DRD1,EFNA2,EFNA3,TMEM35A,ENO2,FABP7,FGF13,FGF14,GABRG2,GAD2,DISC1,CPLX2,PPARGC1A,ATF7,GPR19,GPR26,GRIA1,GRIA2,GRIA4,GRIN1,GRM8,FAM19A2,HRH3,LRRTM1,KCNC2,KCNJ11,L1CAM,FGFBP3,MAOB,MAP6,MAPT,MOV10,MYO7A,NOS1,NPY,HCN1,NTRK2,OPHN1,PENK,NLGN3,ATAT1,KCNIP3,SCN8A,ARX,CPEB3,SLC1A3,SHANK2,SNAP25,KIF13A,SSTR2,ARHGEF9,ATMIN,CRTC1,THRA,CSMD1,RASD2,TRPM2,RNF103,SLC17A7" Mouse Phenotype MP:0002557 abnormal social/conspecific interaction 3.52E-10 2.81E-06 4.61E-08 4.41E-07 132 368 "SYN3,ADORA2A,LRFN2,LRRC7,APBA2,APC,DDO,SPTBN4,NUMB,CACNA1A,CACNA1B,KALRN,CAMK2A,CAMK2B,NEURL1,DLGAP2,DLGAP1,NUMBL,CACNA2D2,RAB3C,CHRNB2,NRXN1,NRXN2,CNR1,WHRN,MAGED1,ZNF521,CSF1,CSF1R,CNTNAP2,RIMS2,ARHGAP32,BRINP1,SNAP91,SRGAP3,DLG4,SHANK1,DSCAM,EDN3,EFNA2,EFNA3,EN2,NBEA,CSPG5,DLL3,TBR1,FYN,GABRA1,GABRB3,GAD2,DISC1,CPLX1,KIRREL3,GLRB,GNAL,GNAO1,MCHR1,GRIA1,GRIA2,GRIA4,GRIN1,GRM1,GSTM5,HNF4G,HNMT,NKD1,DOCK7,LRRTM1,KCNA1,L1CAM,LAMA2,LSAMP,MAG,NAT8L,MAOB,MAP6,MAPT,MBP,MEST,MITF,MYO7A,NOS1,NRCAM,NTRK2,OPHN1,OXTR,PCDH9,ABCB1,NLGN3,SERPINE2,TMIE,JAKMIP1,PMP22,MAGEL2,RELN,RAB3A,FIGN,RGS4,RORB,SAFB,ARX,NLGN1,SLC6A1,SHANK2,SLC12A2,MBD5,SOX1,SP4,NPAS3,STX1A,VPS13A,SYN1,SYN2,TBX15,ZEB1,CRTC1,ATP13A2,SIRT1,CHST8,THRA,NR2E1,TRPM2,TSC1,TSC2,UBE3A,LGI4,ZIC2,FMN2,TUBA1A,PCDH15,TMEM163,PAK5" Mouse Phenotype MP:0009956 abnormal cerebellar layer morphology 4.13E-10 3.30E-06 5.32E-08 5.08E-07 121 330 "ABR,SLC12A5,SORCS2,SPARCL1,SEMA6A,ABCD2,ANK1,ANK3,CNTNAP1,ALS2,APP,SEMA4G,CADPS,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,BID,CDK5R1,SGCE,CACNA1G,CDK5R2,CA8,CACNA1A,CALB1,CBLN1,AIFM1,LGI1,CACNA2D2,GPR37L1,SLIT2,PLAA,PPT2,TPP1,QKI,CNTN1,CP,AKAP12,DNM1,DNM1L,EDIL3,EEF1A2,EGFR,EN2,ENO2,ERBB4,ERCC2,APC2,CEND1,FGF13,AP4B1,GABRA1,B4GALNT1,IP6K3,DNER,GLI2,GLRB,GRIN2C,CIT,IL1RAPL1,IGF1,L1CAM,MAP2,MDM4,AFF1,MYCN,MYO5A,NEUROD1,NFIA,NRCAM,NTRK2,PAX6,PDYN,SERPINE2,PLP1,PLXNB1,ANKRD16,FA2H,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,ROBO2,FBXW7,ACER3,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,SHANK2,TNIK,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UGT8,VLDLR,XRCC4,DPYSL5,LRP8,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0009937 abnormal neuron differentiation 5.95E-10 4.75E-06 7.54E-08 7.21E-07 131 367 "ABR,SYN3,KIDINS220,MRTFA,SEMA7A,APAF1,APBB1,APBB2,APP,ASCL1,NUMB,ATP2B2,NRP2,BMPR1B,CDK5R1,CDK5R2,HAP1,PTBP2,BRSK2,ISPD,CDH2,DCLK1,NUMBL,GPR37L1,ADGRG1,CHN1,CHN2,SLIT2,NGEF,VAX2,CNR1,CNTN1,ZNF521,NCOR1,NCOR2,PLXNA4,ARHGAP32,KIF26A,BRINP1,DCC,DSCAM,EDIL3,EFNA2,EFNB3,CELSR3,ELAVL4,EML1,EMX2,EPHB1,GPHN,ETV1,NRN1,CACNG2,TUBB3,FGFR1,FOXG1,VTI1B,EVL,BRSK1,NKX6-2,GAP43,SRRM4,GFAP,GLI2,GPM6A,GRIA2,RNF165,HMX1,RBPJ,HES5,INSM1,KIF2A,L1CAM,MAPT,MBD1,AFDN,BLOC1S2,MYCN,NCAM1,NEFH,NEUROD1,NFIA,NOS1,NTRK2,PAX6,PDE4B,ENPP2,PLXNB1,MBOAT7,RELN,LAMA1,PTCH1,FEZF2,CRTAC1,RET,KIF7,ROBO1,ROBO2,FBXW7,LRRK2,SLC1A3,CCDC88A,TET1,SLIT1,CPEB4,SMARCC2,SOX1,SOX2,TNIK,SOX10,SOX11,SP2,NMNAT2,MYCBP2,MAPK8IP3,ROBO3,UNC5D,USP22,TLR4,NR2E1,TP53BP2,TRIO,TSC1,VAV2,TRIM9,MAP3K12,GDPD5,PRDM8,PDSS2,RTN4,ST8SIA2" Mouse Phenotype MP:0000841 abnormal hindbrain morphology 6.09E-10 4.86E-06 7.59E-08 7.26E-07 187 572 "ABR,SLC12A5,SORCS2,SPARCL1,SEMA6A,ABCD2,BBOX1,ANK1,ANK3,CNTNAP1,APAF1,ALS2,APP,SEMA4G,SPTBN4,CADPS,ASCL1,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,BID,CDK5R1,FUBP1,SGCE,CACNA1G,CDK5R2,CA8,CACNA1A,CACNA1D,CALB1,CANX,CBLN1,AIFM1,ARHGEF2,DCLK1,LGI1,CACNA2D2,GPR37L1,ADGRG1,SLIT2,PLAA,PPT2,TPP1,QKI,NIPBL,CNTFR,CNTN1,ZNF521,CP,AKAP12,DCC,DNM1,OLIG1,SLC12A6,DSCAM,DYRK1A,DNM1L,E2F6,EBF1,EDIL3,EEF1A2,EGFR,EN2,ENO2,EPB41L1,EPB41L2,ERBB4,ERCC2,APC2,CEND1,ZIC4,PRMT5,FGF13,FGFR1,AP4B1,MEGF10,GABRA1,GABRB3,GALC,B4GALNT1,NKX6-2,IP6K3,DISC1,DNER,GBX2,PPARGC1A,GLI2,GLRB,KDM2B,GNAS,GRIN2C,CIT,IL1RAPL1,IGF1,TUBB2B,KIF2A,L1CAM,SMAD1,SMAD9,MAP2,MAPT,MBP,MDM4,AFF1,MYCN,MYO5A,NCAM1,NEK1,NEUROD1,NEUROD2,NF1,NFIA,NRCAM,NTRK2,OPA1,PAX6,PDYN,SERPINE2,JAKMIP1,PLP1,PLXNB1,ANKRD16,FA2H,POU3F2,CEP41,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,RET,FIGN,RFX4,SETD5,ROBO2,FBXW7,ACER3,WLS,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,SHANK2,TNIK,SOX11,NMNAT2,ZNF423,NPAS3,NFASC,STXBP1,MLC1,MTCL1,ROBO3,CAMTA1,AGTPBP1,TRIM2,RPGRIP1L,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UBE3A,UCHL1,UGT8,VLDLR,XRCC4,ZIC1,ZIC3,DPYSL5,LRP8,PDSS2,EPM2A,GJC2,VANGL2,ST8SIA2" Mouse Phenotype MP:0005402 abnormal action potential 8.77E-10 7.00E-06 1.08E-07 1.03E-06 62 137 "SLC12A5,KCNT1,ANK3,CNTNAP1,ALS2,PRX,MADD,ATP1A2,ATP1A3,ATP2B2,HCN2,CACNA1G,BSN,BAIAP3,CACNA1A,CACNA1D,KALRN,CD86,WHRN,EMX2,KCNMB2,ETV1,FGFR1,GABBR1,GAD2,KCNMB4,GRIA1,GRIA4,GRM7,IL6ST,LRRTM3,KCNA1,KCNA2,KCNC2,KCNJ11,KCNK3,KCNMA1,KCNN3,KCNQ2,KIT,MBP,MYO6,MYO7A,NEFH,NEUROD1,NRCAM,HCN1,NALCN,PMP22,SLC26A11,LRRK2,SCN4B,SCN8A,SIRT2,SOX2,SOX10,NFASC,FGD4,TCF4,KCNT2,PCDH15,KCNAB1" Mouse Phenotype MP:0001454 abnormal cued conditioning behavior 9.32E-10 7.44E-06 1.13E-07 1.08E-06 59 128 "ADD2,PTCHD1,KCTD16,AMPH,APP,KSR1,CAMK2A,CNR1,CREM,FEZ1,CTNND2,CYBB,DBN1,LYPD1,DRD1,TMEM35A,ENO2,ERBB4,NRN1,FGF13,FGF14,TBR1,GABRA2,GABRA5,GAD2,GRIK2,GRM5,LRRTM1,MAPT,GIT1,FXYD6,IDNK,PDE4B,PENK,TMOD2,NLGN3,JAKMIP1,PRKACB,PRKCB,PTPRG,ATXN1,ARX,SLC6A1,SLC6A9,ANKFN1,KIF21B,SP4,NPAS3,STX1A,ARC,WWC1,CRTC1,TSC1,VLDLR,ZIC2,SPIRE1,SLC17A6,FZD3,ST8SIA2" Mouse Phenotype MP:0001406 abnormal gait 1.58E-09 1.26E-05 1.89E-07 1.80E-06 149 437 "ACHE,SLC12A5,PTCHD1,PLA2G6,AMPD2,AMPD3,ANK3,PPFIA2,CNTNAP1,PRX,SPTBN4,ARNTL,ASPA,ATM,ATP1A3,ATP2B2,BCL2L2,HCN2,FGF17,MTMR2,CA8,CACNA1A,CACNA1B,CACNB4,CANX,CAST,CBLN1,RGN,AIFM1,CACNA2D2,CHN1,PLAA,CLCN3,TPP1,QKI,CNTN1,WHRN,CP,DAPK1,DCC,DCTN1,BLOC1S6,DMD,DNM1,SLC12A6,ATN1,DSCAM,EDIL3,ATL1,CACNG7,EFNB3,EGR3,ERBB2,ERCC2,APC2,CEND1,CACNG2,FGF12,FGF14,FGFR1,FGFR3,SUCO,GAA,GABBR1,GABRG2,GAD1,GALC,IP6K3,ATP8A2,CPLX2,GJB1,GLI2,GLRB,GPR22,GRM1,GRM7,CIT,HAS2,ATCAY,ZIC5,ITGA7,ITGAV,KCNA1,KCNA2,KCNB1,KCNMA1,LAMA2,MAG,MBP,MEF2C,MSRA,MYO5A,MYO7A,MYO9A,NF1,NRCAM,PLP1,PMP22,MBOAT7,POU3F4,RELN,LAMA1,PTHLH,PEX2,ROBO2,RORB,ATXN1,ATXN7,SCN8A,ELMOD1,ARX,PREX2,SNCA,SOX10,ZNF423,NPAS3,NFASC,SMOC1,EPB41L3,VPS13A,DDHD2,USP22,ATP13A2,ZNF106,NACC2,TK2,TP53BP2,SEZ6L,PRMT8,TRPC3,NTSR2,TSC1,TSC2,UBE3A,UCHL1,FRRS1L,UGT8,VLDLR,WNT7A,ZIC1,NDRG4,REEP1,LRP8,PCDH15,PDSS2,GJC2,RNF170,FXR1,GAN" Mouse Phenotype MP:0011270 decreased excitatory postsynaptic current amplitude 2.23E-09 1.78E-05 2.61E-07 2.50E-06 23 32 "CADPS,TMEM108,CACNA1A,NRXN1,NRXN2,SNAP91,DLG3,DNM1,SEZ6L2,SEZ6,GRIN1,LRRTM3,LRRTM1,IGSF11,NLGN3,PACSIN1,STX1B,SH3GL2,SH3GL3,NLGN1,STX1A,RIMBP2,SEZ6L" Mouse Phenotype MP:0000788 abnormal cerebral cortex morphology 2.49E-09 1.98E-05 2.88E-07 2.75E-06 134 385 "SORCS2,APAF1,APBB1,APBB2,APP,ARHGAP5,NUMB,ATM,ATP2B2,BBS2,CDK5R1,FUBP1,WASF1,CDK5R2,KALRN,HAP1,PTBP2,BRSK2,AIFM1,CD81,CDH2,DCLK1,ARHGAP33,NUMBL,COPB2,ADGRG1,CHN1,LHX2,PPT2,CLCN3,CNR1,CRMP1,NCOR2,PLXNA4,BRINP1,DLG3,OLIG1,CDON,DPYSL2,DRD1,PDCD6IP,DSCAM,DYRK1A,E2F5,CELSR3,EGFR,ABI2,EML1,EMX2,EPHB1,APC2,ZMYND10,PRMT5,FGF1,FGF13,FOXG1,SMC2,STAMBP,BRSK1,FYN,CHL1,GAD1,GAP43,DISC1,SRRM4,GFAP,PPARGC1A,GPT2,GRIN1,ZIC5,TUBB2B,LRRTM1,KCNA1,KCNJ10,KIF2A,L1CAM,LIG4,MAP2,MAPT,AFDN,MSI1,BLOC1S2,MYCN,RCOR2,NF1,NFIX,NRDC,NTRK2,OPHN1,PAH,PAX6,PCDH9,PLXNB1,MBOAT7,POU3F2,HYDIN,RELN,PEX2,PEX5,FEZF2,PRRT2,RFX4,RGS4,FBXW7,ARX,CCDC88A,SLC20A2,SMARCC2,CDK5RAP2,SNAP25,SOX1,SOX2,SOX11,MYCBP2,NPAS3,MAPK8IP3,CUX2,USP22,TP53BP2,TSC1,TSC2,CADM1,UBE3A,VLDLR,XRCC4,ZIC2,ZIC3,REEP1,MAP3K12,LRP8,TUBA1A,TMEM163,FZD3,ST8SIA2" Mouse Phenotype MP:0009748 abnormal behavioral response to addictive substance 3.02E-09 2.41E-05 3.44E-07 3.29E-06 50 104 "ADORA2A,ADRA1D,ADRA1B,SORCS2,UNC79,ALK,AQP4,ATP1A1,ATP1A3,MPDZ,CACNA1B,CCKBR,CD81,CHRM4,CHRNA4,CHRNB2,TAOK2,CNR1,CLOCK,GPRASP1,DLG4,DRD1,ENO2,PPP1R1B,PDLIM5,FYN,GABRB1,PPARGC1A,GLS,PRLHR,GRIA1,GRIN1,NR3C1,GRM5,KCNC1,MAP6,NOS1,NTRK2,OPRL1,PENK,PRKCG,RGS4,LRRK2,SCN4B,PPP1R9A,SLC6A1,SLC6A9,TACR1,ADGRL3,SLC17A6" Mouse Phenotype MP:0002886 abnormal glutamate-mediated receptor currents 3.28E-09 2.62E-05 3.69E-07 3.52E-06 38 70 "GPR158,CNIH2,RGS9,WASF1,KALRN,SHISA7,LGI1,DLGAP3,NRXN1,NRXN2,AKAP5,DAPK1,CNIH3,DLG4,CACNG7,EFNA3,EPS8,FABP7,CACNG2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK4,GRIN1,GRIN2C,LRRTM1,NLGN3,SERPINE2,STX1B,CLSTN1,SLC6A9,ARC,TCF4,TNFRSF1B,TMEM163,SLC17A6" Mouse Phenotype MP:0011267 abnormal excitatory postsynaptic current amplitude 5.83E-09 4.65E-05 6.46E-07 6.18E-06 26 40 "CADPS,TMEM108,CACNA1A,NRXN1,NRXN2,SNAP91,DLG3,DNM1,SEZ6L2,SEZ6,GABRB3,GAD2,PCLO,GRIN1,LRRTM3,LRRTM1,IGSF11,NLGN3,PACSIN1,STX1B,SH3GL2,SH3GL3,NLGN1,STX1A,RIMBP2,SEZ6L" Mouse Phenotype MP:0003634 abnormal glial cell morphology 7.28E-09 5.81E-05 7.96E-07 7.61E-06 145 431 "ABR,NDRG2,ADRB2,SPARCL1,ABCD2,ALS2,APP,PRX,ASCL1,ASPA,ATP1A3,BID,MYRF,CANX,CAST,ISPD,CBS,CD81,CDH2,CDH18,LGI1,CACNA2D2,ADGRG1,PLAA,CLCN3,QKI,CNTN1,CP,CSF1,TENM4,CSF1R,CNTNAP2,CX3CR1,DCTN1,DMD,OLIG1,DRD1,DRP2,PDCD6IP,EDIL3,EEF1A2,EML1,EMX2,OLIG2,ERBB2,ERCC2,FGF14,FGFR1,FOXG1,EVL,GALC,DNER,GFAP,PPARGC1A,GJB1,HPGDS,GLS,GPM6B,GPR17,GPR34,GRIA2,ACOT7,HES5,IL6ST,ITGAV,KCNA1,KCNJ10,KCNQ3,L1CAM,LAMA2,STMN1,LIFR,MAG,NAT8L,MAPT,MBP,AFF1,AFDN,MOG,CD200,BLOC1S2,ADAM22,MYO7A,NCAM1,NEUROD1,NF1,NFIA,NFE2L2,NKX2-2,NTRK2,OGG1,OPA1,PDGFRA,SERPINE2,PLP1,PMP22,FA2H,POU3F2,KLK6,LAMA1,PTK2,PTPN13,PTPRZ1,PEX5,SH3TC2,LRRK2,SMPD3,ZNF365,SLC4A3,SLC6A8,SLC20A2,SNCA,SOX2,SOX10,SP4,SPP1,NCDN,MAPK8IP3,MLC1,SYNE2,VPS13A,MGRN1,ATMIN,SLC19A3,ATP13A2,CRB1,ZNF106,TK2,NR2E1,TNFRSF1B,IL34,TSC1,TSC2,CADM1,UCHL1,UGT8,MGAT5B,LGI4,ZNF24,CRB2,PDSS2,GJC2,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0000952 abnormal CNS glial cell morphology 7.73E-09 6.17E-05 8.34E-07 7.97E-06 119 337 "ABR,NDRG2,ADRB2,ABCD2,ALS2,APP,ASCL1,ASPA,ATP1A3,MYRF,CANX,CAST,ISPD,CBS,CD81,CDH2,CACNA2D2,ADGRG1,CLCN3,QKI,CP,CSF1,TENM4,CSF1R,CNTNAP2,CX3CR1,DCTN1,DMD,OLIG1,DRD1,PDCD6IP,EDIL3,EML1,EMX2,OLIG2,ERBB2,ERCC2,FGF14,FGFR1,FOXG1,EVL,GALC,DNER,GFAP,GJB1,HPGDS,GLS,GPM6B,GPR17,GPR34,GRIA2,HES5,IL6ST,KCNA1,KCNJ10,KCNQ3,LIFR,MAG,NAT8L,MAPT,MBP,AFDN,MOG,CD200,BLOC1S2,NCAM1,NEUROD1,NF1,NFE2L2,NKX2-2,NTRK2,OGG1,PDGFRA,SERPINE2,PLP1,FA2H,POU3F2,KLK6,LAMA1,PTK2,PTPRZ1,PEX5,LRRK2,SMPD3,ZNF365,SLC4A3,SLC6A8,SLC20A2,SNCA,SOX2,SOX10,SPP1,NCDN,MAPK8IP3,MLC1,SYNE2,MGRN1,ATMIN,SLC19A3,ATP13A2,CRB1,ZNF106,TK2,NR2E1,TNFRSF1B,IL34,TSC1,TSC2,CADM1,UCHL1,UGT8,MGAT5B,ZNF24,CRB2,PDSS2,GJC2,CERS6,VANGL2,ST8SIA2" Mouse Phenotype MP:0000920 abnormal myelination 9.53E-09 7.60E-05 1.01E-06 9.69E-06 81 206 "CNTNAP1,APP,PRX,SPTBN4,ASPA,CADM3,MTMR2,MYRF,CANX,CD86,CACNA2D2,TPP1,QKI,GAL3ST1,CP,CSF1,TENM4,CSF1R,CX3CR1,OLIG1,SLC12A6,DRP2,EEF1A2,OLIG2,ERBB2,ERBB4,FDFT1,ACTL6B,FOXG1,FYN,GABBR1,GALC,NKX6-2,ATP8A2,GFAP,GJB1,GPM6B,GPR17,LINGO1,IGF1,IL6ST,ITGA7,ITGAV,KCNJ10,LAMA2,STMN1,MAG,MBP,PPM1L,MOBP,MOG,ADAM22,NF1,NRCAM,NRDC,NTRK2,OPA1,PDGFRA,PLP1,PMP22,FA2H,POU3F2,PTPRE,PTPRZ1,PEX5,SH3TC2,ZNF365,SIRT2,SOX10,EPB41L3,ERBIN,SEPT8,FGD4,TNFRSF1B,UGT8,MGAT5B,LGI4,ZNF24,REEP1,DOCK8,GJC2" Mouse Phenotype MP:0001898 abnormal long term depression 9.70E-09 7.74E-05 1.02E-06 9.74E-06 46 95 "ADCY8,LRRC7,ADGRB3,RGS9,CDK5R1,WASF1,CAMK2A,CAMK2B,CBLN1,CHRM1,SLC24A2,ARHGEF6,CNR1,PICK1,AKAP5,CALY,EFNB3,CSPG5,GFAP,C1QL1,GRIA1,GRIA2,GRIN1,NR3C1,GRM1,GRM2,LAMA2,MYO5A,NCAM1,NOS1,NLGN3,PRKACB,PRKAR1B,RYR3,SCN4B,CPEB3,SLC8A2,SHANK2,SORCS3,NCDN,ARHGEF9,WWC1,VGF,DPYSL5,ANKS1B,SLC17A6" Mouse Phenotype MP:0000955 abnormal spinal cord morphology 1.14E-08 9.13E-05 1.19E-06 1.13E-05 119 339 "UNC5A,KIDINS220,PLA2G6,ALCAM,APAF1,GAS7,ALS2,ASCL1,NRP2,CDK5R1,MYRF,CDK5R2,CACNB4,CANX,ISPD,CDH2,NOG,CRLF1,CACNA2D2,CHN1,SLIT2,LHX2,CNTFR,CP,CLIP3,TENM4,RIMS2,DCC,DCTN1,OLIG1,SLC12A6,EDIL3,EEF1A2,EFNB3,EGR3,OLIG2,GPHN,ERBB2,ERBB4,CACNG2,FGF14,FGFR1,GALC,ATP8A2,SRRM4,GBX2,GFAP,GFRA1,GLI2,GLRB,GRIA1,GRIA2,GRM7,KIF3A,RNF165,TLX1,ATCAY,IGF1,RBPJ,HES5,KCNJ10,KIF5A,KIF5C,KLC1,L1CAM,LAMA2,LIFR,SMAD9,MAPT,MOG,NEFH,NFIA,NKX2-2,NOS1,NOVA1,NPR2,NTRK2,PAX6,PCSK5,PDE4B,PIK3C2A,PTCH1,RET,RFX4,KIF7,ROBO1,ROBO2,DRAXIN,SCN8A,FUZ,AMBRA1,SLC1A2,SLIT1,CPEB4,IFT122,SNCA,SOX2,SOX10,NMNAT2,MYCBP2,KIF1B,ROBO3,CNTN2,CUX2,ZNF106,TK2,TP53BP2,TTPA,UCHL1,ZIC2,ZNF24,ELFN1,REEP1,MAP3K12,LRP8,GDPD5,FZD3,VANGL2,GAN" Mouse Phenotype MP:0004859 abnormal synaptic plasticity 1.38E-08 1.10E-04 1.42E-06 1.35E-05 37 70 "ADD2,LRFN2,NRP2,KSR1,CDK5R1,CAMK2A,CAMK2B,CLCN3,CNR1,PICK1,AKAP5,DBN1,SNAP91,DLG4,DRD1,MBNL2,DPYSL4,CPLX2,CPLX1,GRIA1,GRIA2,GRIN1,MAP6,NTRK2,NLGN3,RASGRF1,PRRT2,SLC8A2,STX1A,ARHGEF9,SYP,RIMBP2,UCHL1,VLDLR,CLIP2,ELFN1,ANKS1B" Mouse Phenotype MP:0001486 abnormal startle reflex 1.85E-08 1.48E-04 1.87E-06 1.79E-05 98 267 "SLITRK1,ADRA1D,LRFN2,KIAA1324,ASPA,ATP1A3,ATP2B2,B3GALT2,BBS2,CACNA1B,KALRN,CAST,CCK,USP2,COX4I1,ZBTB24,DLG4,SLC12A6,DRD1,EDIL3,EDNRA,EFNA2,EFNA3,ADGRV1,CACNG2,KIAA1109,FGF11,FOXO3,EVL,SGIP1,FYN,GABRA1,GABRA3,DISC1,ATP8A2,CPLX2,GATM,PPARGC1A,NTNG2,GLRB,GNAO1,ATF7,GRIA4,GRIK5,GRIN1,CACFD1,GRIN2D,ATE1,NXPH3,CPT1C,KCNA1,KCNJ10,MAG,MBP,MYO6,MYO7A,NF1,TMOD2,NLGN3,TMIE,GPSM2,PLP1,POU3F4,PRODH,LAMA1,PTPRG,FIGN,SCN8A,ELMOD1,SH3BP2,FBXO11,PREX2,SLC6A1,SLC8A3,SLC12A2,SP4,BEX1,NPAS3,LRRC4,STX1A,AJAP1,JMJD6,PLCB1,TCF4,AP4E1,CSMD1,NTSR2,TSC1,SSBP2,ZIC2,RNF103,PCDH15,NAV2,SLC17A7,TMEM163,PDSS2,EPM2A,FZD3" Mouse Phenotype MP:0001462 abnormal avoidance learning behavior 2.08E-08 1.66E-04 2.05E-06 1.96E-05 43 88 "ADCY8,PTCHD1,ADRA1B,DOC2A,APBB1,APP,ATP1A3,CACNA1B,KALRN,CAMK2A,CHRNB2,CNR1,LYPD1,SRGAP3,DRD1,TBR1,FYN,GABBR1,GABRA1,JPH4,DISC1,GHR,MCHR1,GRIN1,GRM7,NTRK2,OPRL1,PAK3,MAPK3,RASGRF1,RYR3,ARX,SLC6A1,SLC6A9,SORCS3,SP4,ARC,WWC1,SLC17A6,EPM2A,PAK5,ST8SIA2,JPH3" Mouse Phenotype MP:0009747 impaired behavioral response to xenobiotic 2.08E-08 1.66E-04 2.05E-06 1.96E-05 43 88 "ADCY5,ADORA2A,ADRA1D,ADRA1B,UNC79,AQP4,CACNA1G,CACNA1B,CACNA2D1,CACNB4,CCKBR,CD81,CHRM4,CHRNA4,TAOK2,CNR1,GPRASP1,DGKB,DLG4,NR1D2,DRD1,ENO2,PPP1R1B,PDLIM5,GABRA1,GABRA2,GABRA4,GABRB3,GABRG2,MCHR1,GRIN1,GRM5,HLF,KCNK2,KIT,OPRL1,PLCL1,PRKCG,RGS4,LRRK2,SLC6A9,TACR1,SLC17A6" Mouse Phenotype MP:0001413 abnormal response to new environment 2.13E-08 1.70E-04 2.08E-06 1.99E-05 88 233 "ADORA2A,ADRA1B,PLA2G6,APBA2,ALS2,APP,CHRD,ATP1A1,ATP1A3,STX16,BCL7A,CANX,CHRNA4,CHRNB2,CLCN3,CNR1,MAGED1,CLOCK,ERC2,BRINP1,SIRPA,OLIG1,SLC12A6,DYRK1A,EFNA2,EFNA3,ENO2,ERCC2,FGF12,FGF14,GABBR1,CHL1,JPH4,DISC1,CPLX2,GNAS,GRIA1,GRIA2,GRIA4,GRIN1,GRM1,GRM8,HSD17B1,HTR5A,LRRTM1,KCNC1,KCNJ11,L1CAM,LSAMP,MAOB,NPY,OPA1,OPHN1,OPRL1,PDE4B,PDE1B,ZDHHC8,SERPINI1,SH3KBP1,PKIA,RGS7,RORB,ATXN1,ARX,CCDC88A,SP4,NPAS3,SSTR2,ARHGEF9,TAF6,WSCD1,TCF4,DMXL2,CRTC1,SLC44A1,NR2E1,PRMT8,ZNF142,GDPD5,NAV2,TMEM163,SLC17A6,PAK5,CERS6,AAAS,ST8SIA2,SLC4A10,JPH3" Mouse Phenotype MP:0012317 impaired conditioning behavior 4.88E-08 3.90E-04 4.69E-06 4.49E-05 56 130 "PTCHD1,ADRA1B,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,CACNA1B,CAMK2A,CAMK2B,SHISA7,CHRNA4,TAOK2,CNR1,DBN1,DRD1,DYRK1A,EFNA3,TMEM35A,ENO2,ERBB4,NRN1,PPP1R1B,FGF13,FGF14,GAD2,GALR1,GRIA2,GRIN1,GRIN2C,MAPT,GIT1,FXYD6,IDNK,PDE4B,PDYN,NLGN3,RASGRF1,RGS4,CARF,ITSN1,ARX,SLC6A1,SLC6A8,CCDC88A,ANKFN1,KIF21B,SP4,STX1A,TACR1,WWC1,CRTC1,UBE3A,ZIC2,SLC17A6,FZD3" Mouse Phenotype MP:0008143 abnormal dendrite morphology 6.48E-08 5.17E-04 6.16E-06 5.89E-05 84 224 "SLC12A5,LRFN2,KIDINS220,GPR158,LRRC7,SEMA6A,NUMB,TMEM108,ATM,BCL2L2,NRP2,CACNA1A,KALRN,CAMK2A,SEPT7,ARHGAP33,DLGAP2,JAM2,SLIT2,PLAA,ARHGEF6,CNTN1,CRMP1,DBN1,SRGAP3,DLG4,GRIN3A,DNM1,DPYSL2,EDIL3,OLIG2,SEZ6,CEND1,NRN1,ACTL6B,FOXG1,POMT1,CAMKK2,GABRB3,IP6K3,GRIA1,GRIK4,CPT1C,LRRTM3,LRRTM1,MAPT,MOV10,GIT1,MYO5A,NF1,NOS1,NTRK2,OPHN1,PCDH9,PDE4B,ZDHHC8,SEMA5B,LAMA1,ROBO2,LRRK2,ATXN1,CPEB3,CLSTN1,SLC1A3,PREX2,CCDC88A,SHANK2,CPEB4,KIF21B,ZNF423,STAU1,MTCL1,AGTPBP1,THRA,PRMT8,TRPC3,TSC1,TSC2,UBE3A,ELFN1,DPYSL5,SPIRE1,TUBA1A,SLC17A6" Mouse Phenotype MP:0003008 enhanced long term potentiation 7.50E-08 5.99E-04 7.04E-06 6.73E-05 34 65 "LRFN2,CHRD,WASF1,CAMK2A,CNR1,AKAP5,DLG4,ERBB4,BAIAP2,NBEA,GFAP,GRIA2,GRIK1,ITPKA,KCNJ10,LAMA2,NELL2,OPRL1,PDE4B,TMOD2,PTN,PTPRZ1,KCNIP3,RYR3,CLSTN1,SLC8A2,SHANK2,ARHGEF9,ARC,TCF4,ICAM5,TSC2,KCNAB1,TMEM163" Mouse Phenotype MP:0003997 tonic-clonic seizures 9.85E-08 7.86E-04 9.14E-06 8.74E-05 38 77 "SYN3,SLC12A5,HCN2,LGI1,CLCN3,PLPPR4,SNAP91,DNM1,MBNL2,GABBR1,GABRA1,GAD2,B4GALNT1,DCLK2,GNG3,GRIA2,GRIK4,GRIN1,ATE1,HLF,KCNA1,KCNC2,KCNJ10,KCNJ11,KCNQ2,NEUROD1,NEUROD2,PLP1,PACSIN1,ARX,ST8SIA1,SST,SYN1,SYN2,SZT2,UBE3A,CELF4,AP3B2" Mouse Phenotype MP:0002200 abnormal brain ventricular system morphology 1.08E-07 8.60E-04 9.89E-06 9.45E-05 132 399 "ADD1,KIDINS220,NME5,CC2D2A,APAF1,ARHGAP5,ASPA,NUMB,BBS2,NRP2,CDK5R1,WASF1,PTBP2,BRSK2,DCLK1,NUMBL,CHN1,CLCN3,CP,NCOR1,CSF1R,ZEB2,SRGAP3,KIF19,ARNT2,SLC29A4,TRAPPC9,CDON,DNM2,DRD1,PDCD6IP,DSCAM,DNM1L,E2F5,EDIL3,EML1,EMX2,ZMYND10,PRMT5,FOXG1,VTI1B,EVL,AK8,DLL3,BRSK1,CHL1,GBX2,GDF1,GFAP,GLDC,GLI2,KDM2B,GPM6B,KIF3A,HSF2,ZIC5,LRRCC1,HES5,TUBB2B,ITGAV,KCNJ10,KIF2A,L1CAM,MDM4,PPM1L,MSI1,BLOC1S2,MYO9A,NEK1,NFIA,NFIX,NODAL,NRDC,ODF2,OPA1,OPHN1,PAX6,PKD1,PLP1,PLXNB1,MBOAT7,POU3F2,MAPK8,MAPK9,HYDIN,PTCH1,CCDC40,RFX4,RGS4,KIF7,ZC3H14,ATAT1,WLS,ATXN1,SCN8A,KIF27,ARX,FUZ,TET1,CDK5RAP2,SOX1,SOX2,SOX3,SP2,MYCBP2,ZNF423,SPTAN1,NPAS3,MAPK8IP3,CNTN2,ZEB1,RPGRIP1L,AP4E1,NR2E1,TP53BP2,RBFOX2,TSC1,VAV2,TOM1L2,VLDLR,CLIP2,ZIC2,CRB2,SPHK2,MAP3K12,LRP8,TMEM163,SLC17A6,FZD3,VANGL2,ST8SIA2,SLC4A10" Mouse Phenotype MP:0000822 abnormal brain ventricle morphology 1.23E-07 9.83E-04 1.12E-05 1.07E-04 113 330 "KIDINS220,APAF1,ARHGAP5,ASPA,NUMB,BBS2,CDK5R1,WASF1,PTBP2,BRSK2,DCLK1,NUMBL,CHN1,CLCN3,CP,NCOR1,CSF1R,ZEB2,SRGAP3,KIF19,ARNT2,SLC29A4,TRAPPC9,CDON,DRD1,PDCD6IP,DSCAM,DNM1L,E2F5,EDIL3,EML1,EMX2,ZMYND10,PRMT5,FOXG1,VTI1B,EVL,AK8,DLL3,BRSK1,CHL1,GBX2,GDF1,GLDC,KDM2B,GPM6B,HSF2,ZIC5,HES5,TUBB2B,KCNJ10,KIF2A,L1CAM,MDM4,PPM1L,MSI1,BLOC1S2,MYO9A,NEK1,NFIA,NFIX,NODAL,NRDC,ODF2,OPA1,OPHN1,PAX6,PKD1,PLP1,PLXNB1,MBOAT7,POU3F2,MAPK8,MAPK9,HYDIN,RFX4,RGS4,ZC3H14,ATAT1,WLS,ATXN1,SCN8A,ARX,FUZ,TET1,CDK5RAP2,SOX2,SOX3,MYCBP2,ZNF423,SPTAN1,NPAS3,MAPK8IP3,CNTN2,ZEB1,RPGRIP1L,AP4E1,NR2E1,TP53BP2,TSC1,VLDLR,CLIP2,ZIC2,CRB2,SPHK2,MAP3K12,LRP8,TMEM163,SLC17A6,FZD3,VANGL2,ST8SIA2,SLC4A10" Mouse Phenotype MP:0020573 abnormal corpus callosum size 1.91E-07 1.52E-03 1.71E-05 1.63E-04 29 53 "APP,ARHGAP5,CDK5R1,WASF1,DCLK1,PLAA,NIPBL,SLC12A6,EMX2,EPHB1,VTI1B,FYN,GFAP,GPM6B,PPM1L,PLP1,PLXNB1,ROBO1,ROBO2,DRAXIN,SOX2,MYCBP2,RPGRIP1L,AP4E1,CLIP2,ZIC2,TRIM9,MAP3K12,FZD3" Mouse Phenotype MP:0001364 decreased anxiety-related response 2.12E-07 1.70E-03 1.88E-05 1.80E-04 64 161 "ADCY8,ADCYAP1R1,GPR158,APBA2,ASPA,ATP1A3,B3GALT2,WASF1,CACNA1B,DDR1,KALRN,CAMK2A,CAMK2B,CCKBR,CHRNB2,NDST3,AKAP5,ZNF521,CREM,BRINP1,KIAA0319,SNAP91,DLG4,EFNA2,EFNA3,ERBB4,KIAA1109,FGF14,CHL1,DISC1,PCSK1N,MCHR1,TPPP,GRIA1,NR3C1,HRH3,SYNPO,HTR2A,KCNJ11,L1CAM,LSAMP,MAPT,GIT1,OPHN1,PDE4B,PDYN,JAKMIP1,PRKCG,PRKCZ,ARX,NPAS3,STX1A,DNAJC9,TAC1,TACR1,ADGRL3,TCF4,NR2E1,NR2C2,TSC1,ELFN1,TUBA1A,TMEM163,SLC4A10" Mouse Phenotype MP:0009358 environmentally induced seizures 2.36E-07 1.89E-03 2.07E-05 1.98E-04 27 48 "SYN3,ADORA1,ATP1A3,NRP2,CACNA1A,LGI1,TPP1,CNTNAP2,HDAC4,ADGRV1,FGF13,FYN,GABBR1,B4GALNT1,GNG3,GRM5,HLF,MBP,PAH,PLP1,PRRT2,ST8SIA1,SYN1,SYN2,TSC2,UBE3A,ELFN1" Mouse Phenotype MP:0009944 abnormal olfactory lobe morphology 2.76E-07 2.21E-03 2.40E-05 2.29E-04 72 189 "MRTFA,SEMA7A,ASCL1,NUMB,ATP1A2,NRP2,CDK5R1,CDK5R2,PTBP2,NUMBL,SLIT2,LHX2,CNGA3,OLIG1,DSCAM,EDIL3,EFNA2,EFNA3,EGFR,EMX2,ENO2,APC2,FOXG1,TBR1,FYN,GAD1,KIRREL3,CIT,DHX35,IGF1,TUBB2B,LAMA2,NCAM1,NCAM2,NEK1,HCN1,PAX6,POU3F2,HYDIN,RELN,FEZF2,CRTAC1,RGS4,RIC8B,SETD5,ROBO1,ROBO2,RPL38,SALL1,ARX,CCDC88A,SLIT1,CDK5RAP2,SOX1,SOX2,SOX10,SOX11,SP2,NMNAT2,ZNF423,ATP11A,AGTPBP1,ZEB1,RPGRIP1L,NR2E1,TP53BP2,TRIO,VLDLR,ZIC2,MAP3K12,LRP8,ST8SIA2" Mouse Phenotype MP:0002918 abnormal paired-pulse facilitation 3.36E-07 2.68E-03 2.88E-05 2.76E-04 36 74 "ADD2,APBA2,CHRD,CACNA1A,CAMK2A,CHRM1,RAB3C,CNR1,SNPH,SIRPA,SNAP91,DLG4,CSPG5,GRIA2,GRIK2,GRIK3,GRIK4,GRIK5,LRRTM3,KCNA1,STXBP5,MAPT,MEF2C,MAPK9,PTN,RAB3A,ATXN1,SLC8A2,RAB3GAP1,SNAP25,TNIK,STX1A,SYN1,SYP,RIMBP2,UCHL1" Mouse Phenotype MP:0000812 abnormal dentate gyrus morphology 3.40E-07 2.72E-03 2.89E-05 2.76E-04 50 117 "FZD9,MRTFA,APBB1,APBB2,CADPS,ATP1A3,CDK5R1,CDK5R2,CAMK2A,DCLK1,ZNF521,BRINP1,DRD1,DYRK1A,ABI2,EMX2,ENO2,APC2,FABP7,FGF13,FGF14,FOXG1,FYN,GFAP,DCLK2,CIT,MAPT,MBD1,NEUROD1,NFIX,PROX1,RELN,FEZF2,ATAT1,LRRTM4,ARX,SLC6A8,CCDC88A,SOX1,SOX2,SOX11,SP4,NCDN,NR2E1,TRIO,TSC1,VLDLR,LRP8,TUBA1A,UBE3B" Mouse Phenotype MP:0003232 abnormal forebrain development 3.56E-07 2.84E-03 2.99E-05 2.86E-04 92 260 "FZD9,PCDH19,APAF1,APBB1,APBB2,APC,PRX,ASCL1,CHRD,NUMB,NRP2,CDK5R1,CDK5R2,PTBP2,BRSK2,CDH2,NOG,NUMBL,ADGRG1,CHN2,LHX2,ZNF521,NCOR2,BOC,DLG3,CDON,EDIL3,CELSR3,APH1A,EML1,EMX2,F3,DLC1,PRMT5,FGFR1,FOXG1,EVL,BRSK1,GBX2,GLI2,CECR2,SYNPO,ZIC5,HES5,IL6ST,TUBB2B,KIT,MBD1,AFDN,BLOC1S2,MYCN,NEUROD1,NODAL,NTRK2,OPA1,PAX6,ENPP2,PIK3C2A,PLXNB1,POU3F2,MED1,MAPK8,MAPK9,RELN,PTCH1,FEZF2,TMEM100,FBXW7,ARX,AMBRA1,TET1,CDK5RAP2,SOX2,SOX11,SP2,MYCBP2,SPTAN1,MAPK8IP3,MLST8,CNTN2,USP22,TEK,TIE1,NR2E1,PARD3,TP53BP2,VLDLR,ZIC2,LRP8,TMEM163,VANGL2,IFT88" Mouse Phenotype MP:0000745 tremors 3.94E-07 3.15E-03 3.28E-05 3.13E-04 106 311 "ACHE,PLA2G6,ABCD2,ANK1,ANK3,CNTNAP1,KCNAB2,MIER1,SPTBN4,ASPA,ATP1A3,ATP2B2,ADAM23,HCN2,BMP7,SYNJ1,MTMR2,CACNA1G,WASF1,MYRF,CA8,CACNA1A,CANX,AIFM1,CACNA2D2,PLAA,CLCN3,NRXN1,TPP1,VAX2,QKI,GAL3ST1,CSF1,TENM4,DMD,DNM1,EEF1A2,EGR3,OLIG2,ERCC2,FDFT1,PRMT5,GABRA1,GABRB3,GABRG2,GALC,ATP8A2,SRRM4,GJB1,GLI2,GLRB,GNAO1,GNAS,GPM6B,GRIA2,GRM1,GRM7,CIT,KCNA1,KCNA2,KCNC1,KCNJ10,KCNMA1,KIF5A,LAMA2,MAG,MAPT,MBP,MOG,DBNL,NFIA,NOVA1,NRCAM,OPA1,CLDN11,PDGFRA,ABCB1,PLP1,PRIMPOL,PMP2,PMP22,RELN,PEX5,SH3TC2,ATXN7,SCN8A,ELMOD1,SLC6A1,SNAP25,ANKFN1,SOX10,ZNF423,AGTPBP1,IQCE,TRIM2,ZNF106,TK2,TSC1,TTPA,UCHL1,UGT8,VLDLR,ZNF24,LRP8,TMEM163,GJC2" Mouse Phenotype MP:0004769 abnormal synaptic vesicle morphology 4.04E-07 3.22E-03 3.30E-05 3.15E-04 31 60 "MADD,CADPS,KIF1A,BSN,CAMK2A,CLCN3,ERC2,RIMS2,SIRPA,DNAJC6,SNAP91,DNM1,CACNG2,NBEA,PCDH17,PCLO,IGSF21,LRRTM1,MAP6,PACSIN1,STX1B,SH3GL2,SH3GL3,NAPB,KIF1B,STX1A,SYN2,TNR,SLC30A3,SLC17A7,SLC17A6" Mouse Phenotype MP:0011966 abnormal auditory brainstem response waveform shape 4.05E-07 3.23E-03 3.30E-05 3.15E-04 24 41 "AQP4,SPTBN4,ASPA,ATP2B2,CACNA1D,NIPBL,SLC4A7,CSF1,LRIG1,DMD,DNM1,GABRA5,GABRB3,CPLX1,NTNG2,GPM6B,IGF1,MBP,CLDN11,PLP1,SCN8A,SLC1A3,LRRC4,WBP2" Mouse Phenotype MP:0008225 abnormal anterior commissure morphology 4.36E-07 3.48E-03 3.48E-05 3.33E-04 32 63 "MRTFA,APP,ARHGAP5,NRP2,DCLK1,PLXNA4,EBF1,CELSR3,EMX2,EPHB1,TUBB3,FOXG1,VTI1B,TBR1,GPM6B,TUBB2B,MAP2,PPM1L,PLP1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,SOX1,MYCBP2,MAPK8IP3,CNTN2,NR2E1,MAP3K12,SEMA3B,FZD3" Mouse Phenotype MP:0008220 abnormal ventral commissure morphology 4.36E-07 3.48E-03 3.48E-05 3.33E-04 32 63 "MRTFA,APP,ARHGAP5,NRP2,DCLK1,PLXNA4,EBF1,CELSR3,EMX2,EPHB1,TUBB3,FOXG1,VTI1B,TBR1,GPM6B,TUBB2B,MAP2,PPM1L,PLP1,FEZF2,ROBO1,ROBO2,DRAXIN,ITSN1,SOX1,MYCBP2,MAPK8IP3,CNTN2,NR2E1,MAP3K12,SEMA3B,FZD3" Mouse Phenotype MP:0004753 abnormal miniature excitatory postsynaptic currents 4.66E-07 3.72E-03 3.69E-05 3.53E-04 50 118 "SLC12A5,LRFN2,DOC2A,CNIH2,MADD,CADPS,CHRD,TMEM108,CACNA1A,CACNA1B,KALRN,SHISA7,CDH8,LGI1,DLGAP2,CHRM1,NRXN1,CNIH3,PLPPR4,SNAP91,DNM1,NRN1,CACNG3,CACNG2,NBEA,CPLX2,CPLX1,GRIA1,GRIN1,GRIN2C,LRRTM3,LRRTM1,MAPT,NLGN3,PACSIN1,PRRT2,STX1B,LRRTM4,PPP1R9A,SH3GL2,SH3GL3,SHANK2,SNAP25,TNIK,STX1A,ARC,SYN2,SYT1,CELF4,SLC17A7" Mouse Phenotype MP:0000781 decreased corpus callosum size 4.83E-07 3.86E-03 3.78E-05 3.62E-04 28 52 "APP,ARHGAP5,CDK5R1,WASF1,DCLK1,PLAA,NIPBL,SLC12A6,EMX2,EPHB1,VTI1B,FYN,GFAP,GPM6B,PPM1L,PLP1,PLXNB1,ROBO1,ROBO2,DRAXIN,SOX2,MYCBP2,RPGRIP1L,AP4E1,CLIP2,ZIC2,MAP3K12,FZD3" Mouse Phenotype MP:0000743 muscle spasm 5.00E-07 3.99E-03 3.88E-05 3.71E-04 35 72 "CNTNAP1,NRP2,BID,SGCE,BSN,CACNA1A,CACNB4,CACNA2D2,PPT2,DRD1,EML1,GABRA1,GAD2,PPARGC1A,GLRB,GPM6B,GRM1,CIT,ATCAY,KCNA1,KCNC1,KCNC2,KCNJ11,LAMA2,MYO5A,PLP1,HYDIN,RELN,RYR1,ATXN7,SCN8A,ARX,SNAP25,EPM2A,GAN" Mouse Phenotype MP:0009046 muscle twitch 5.11E-07 4.08E-03 3.92E-05 3.75E-04 36 75 "CNTNAP1,NRP2,BID,SGCE,BSN,CACNA1A,CACNB4,CACNA2D2,PPT2,DRD1,EML1,GABRA1,GAD2,GALC,PPARGC1A,GLRB,GPM6B,GRM1,CIT,ATCAY,KCNA1,KCNC1,KCNC2,KCNJ11,LAMA2,MYO5A,PLP1,HYDIN,RELN,RYR1,ATXN7,SCN8A,ARX,SNAP25,EPM2A,GAN" Mouse Phenotype MP:0000243 myoclonus 6.20E-07 4.95E-03 4.72E-05 4.51E-04 21 34 "NRP2,BID,SGCE,BSN,CACNA2D2,DRD1,EML1,GABRA1,GAD2,PPARGC1A,CIT,KCNA1,KCNC1,KCNC2,KCNJ11,MYO5A,ATXN7,SCN8A,ARX,SNAP25,EPM2A" Mouse Phenotype MP:0008503 abnormal spinal cord grey matter morphology 6.43E-07 5.13E-03 4.84E-05 4.63E-04 83 231 "UNC5A,KIDINS220,PLA2G6,ALCAM,APAF1,GAS7,ALS2,ASCL1,CDK5R1,CDK5R2,CACNB4,CRLF1,CACNA2D2,CHN1,LHX2,CNTFR,CP,CLIP3,RIMS2,DCTN1,OLIG1,EEF1A2,EFNB3,EGR3,OLIG2,GPHN,ERBB2,ERBB4,CACNG2,FGFR1,ATP8A2,SRRM4,GBX2,GFRA1,GLI2,GLRB,GRIA2,GRM7,RNF165,TLX1,ATCAY,IGF1,RBPJ,KIF5A,KIF5C,L1CAM,LIFR,SMAD9,MAPT,NEFH,NKX2-2,NOS1,NTRK2,PAX6,PTCH1,RET,RFX4,KIF7,DRAXIN,SCN8A,FUZ,SLC1A2,CPEB4,IFT122,SNCA,SOX2,SOX10,NMNAT2,MYCBP2,KIF1B,ROBO3,CNTN2,CUX2,ZNF106,TK2,TTPA,UCHL1,ZIC2,REEP1,MAP3K12,LRP8,GDPD5,GAN" Mouse Phenotype MP:0000953 abnormal oligodendrocyte morphology 6.49E-07 5.18E-03 4.84E-05 4.63E-04 31 61 "ASPA,MYRF,QKI,CSF1,TENM4,OLIG1,OLIG2,ERBB2,GALC,GFAP,GJB1,GPM6B,GPR17,HES5,KCNJ10,MAG,MBP,MOG,NF1,NKX2-2,PDGFRA,PLP1,KLK6,PTPRZ1,PEX5,ZNF365,SOX10,UGT8,MGAT5B,ZNF24,GJC2" Mouse Phenotype MP:0001968 abnormal touch/ nociception 6.64E-07 5.30E-03 4.91E-05 4.69E-04 103 303 "ADCY8,SLC12A5,ADORA1,ADORA2A,ADORA3,KCNT1,PRX,MADD,ARRB2,ASPA,ATP1A2,ATP1A3,KIF1A,BBS2,HCN2,CDK5R1,CDK5R2,CACNA1A,CACNA1B,BRSK2,CCKBR,P2RX6,CDH8,ADGRG1,ASIC3,CHRNA4,CHRNB2,TPP1,HOMER3,CNR1,WHRN,CNTNAP2,ARHGEF4,FRMPD4,HDAC4,GIT2,DLG2,DLG4,SLC12A6,EDNRB,KMT5B,FGF11,SEMA6C,FLNC,NBEA,BRSK1,GABBR1,GABRA2,GABRA4,GNAO1,PRLHR,GRIA1,GRIA2,GRIA4,GRIK1,GRIK5,GRM5,GRM7,MAP4K5,KCNA1,KCNA6,KCND2,L1CAM,NBL1,HCN1,OPRL1,P2RX7,PCSK2,PIRT,PDYN,PENK,RETREG1,PRKAR1B,PRKCG,PTPRG,PTPRZ1,RGS4,KCNIP3,RYR1,S100B,ELMOD1,ARX,SLC6A9,SNAP25,SOX10,MYCBP2,SPP1,KIF1B,ERBIN,TAC1,TACR1,PHF24,ZNF106,TLR4,NR2C2,NTSR2,TSC1,UCHL1,KCNT2,NAV2,SLC17A7,SLC17A6,RNF170" Mouse Phenotype MP:0000875 abnormal cerebellar Purkinje cell layer 6.91E-07 5.51E-03 5.06E-05 4.84E-04 93 267 "SLC12A5,SPARCL1,ABCD2,ANK1,ANK3,ALS2,APP,NCOA1,NUMB,ASTN1,ATM,ATP2B2,BCL2L2,FGF17,CDK5R1,SGCE,CACNA1G,CDK5R2,CACNA1A,CALB1,AIFM1,CACNA2D2,GPR37L1,SLIT2,PLAA,TPP1,QKI,CNTN1,CP,AKAP12,DNM1,DNM1L,EDIL3,EEF1A2,EGFR,ERCC2,APC2,CEND1,AP4B1,GABRA1,B4GALNT1,IP6K3,DNER,GLI2,GLRB,CIT,IGF1,MAP2,MDM4,AFF1,MYCN,MYO5A,NEUROD1,NTRK2,PAX6,ANKRD16,FA2H,RELN,LAMA1,PTK2,PEX2,KHDRBS2,ROBO2,FBXW7,ACER3,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,RBFOX2,PRMT8,TRIO,TRPC3,TSC1,TSC2,UGT8,VLDLR,DPYSL5,LRP8,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0004792 abnormal synaptic vesicle number 8.11E-07 6.47E-03 5.89E-05 5.63E-04 28 53 "MADD,CADPS,KIF1A,BSN,CAMK2A,ERC2,RIMS2,SIRPA,DNAJC6,SNAP91,DNM1,CACNG2,NBEA,PCDH17,PCLO,IGSF21,MAP6,PACSIN1,STX1B,SH3GL2,SH3GL3,NAPB,KIF1B,STX1A,SYN2,TNR,SLC17A7,SLC17A6" Mouse Phenotype MP:0003088 abnormal prepulse inhibition 1.11E-06 8.84E-03 7.96E-05 7.62E-04 72 195 "ADRA1D,LRFN2,MTA3,LRRC7,PPFIA2,ARRB1,ASPA,TMEM108,ATP1A3,ATP2A2,ATP2B2,KALRN,CCK,NRXN1,ZNF521,PLEKHM1,KIAA0319,SRGAP3,GRIN3A,OLIG1,SLC12A6,EDNRA,EFNA2,EFNA3,ENO2,ERBB4,ADGRV1,EZH1,CLVS1,FABP7,FOXO3,PDLIM5,GABBR1,GABRA3,GABRA5,GAD2,DISC1,STARD10,ATF7,GRIA4,GRIN1,GRM8,PTPN5,IGSF21,FRMD5,ACOT7,IRF8,KCNQ2,MAG,MAP6,MAT2A,NRCAM,NTRK2,PCDH9,TMOD2,ZDHHC8,RELN,ELMOD1,SLC6A1,CCDC88A,SNAP25,NPAS3,NCDN,PLCB1,TCF4,AP4E1,NTSR2,ZIC2,ANKS1B,RNF103,TMEM163,FZD3" Mouse Phenotype MP:0002229 neurodegeneration 1.33E-06 1.06E-02 9.45E-05 9.04E-04 157 511 "PLA2G6,ABCD2,AMPD2,AMPD3,ANK1,ANK3,APAF1,ALS2,APP,SPTBN4,ASPA,ATM,ATP2B2,KIF1A,RGS9,PROM1,SYNJ2,MTMR2,CACNA1A,CACNA1D,CACNB2,HAP1,PTBP2,AIFM1,LGI1,CACNA2D2,ASIC3,CHM,CLCN3,TPP1,QKI,TMEM184B,CNGA3,WHRN,SLC4A7,CP,CSF1R,CX3CR1,CYBB,DCTN1,HEPH,SLC12A6,ATN1,USH1C,EDIL3,EDNRB,EEF1A2,EGR3,OLIG2,GPHN,ERCC2,ADGRV1,FGF14,FOXG1,VTI1B,FLT1,STAMBP,GABRA5,CHL1,GABRB3,GALC,B4GALNT1,NKX6-2,ATP8A2,SRRM4,GFAP,GFRA1,PPARGC1A,GJB1,GPM6B,GPR37,GRIA2,GRID1,GRM7,ACOT7,HPCA,ATCAY,ITGA7,ITGAV,KCNJ10,KIF5A,KIT,KLC1,STMN1,MAG,NAT8L,MAPT,MBP,MITF,AFF1,MSR1,MYO6,MYO7A,NCAM1,NDP,NEFH,NF1,NFE2L2,NTRK2,NTRK3,OGG1,OPA1,CLDN11,ABCB1,TMIE,RETREG1,PLP1,ANKRD16,PMP22,POLG,POU3F4,RELN,SH3TC2,OXR1,RDX,RFX3,ROM1,RORB,RPE65,ACER3,LRRK2,LGR4,ATXN1,ATXN7,SCN8A,SH3GL2,SLC1A3,SLC8A3,SNCB,SNCA,SOX2,SPATA7,SOX10,NMNAT2,ELOVL4,STXBP1,MTCL1,CAMTA1,AGTPBP1,ATMIN,TRIM2,SLC19A3,ZNF106,TSC2,TTPA,TUB,UCHL1,UGT8,VAV2,VLDLR,REEP1,LRP8,PCDH15,PDSS2,EPM2A,GJC2,MSRB3" Mouse Phenotype MP:0004077 abnormal striatum morphology 1.38E-06 1.10E-02 9.77E-05 9.34E-04 42 96 "MRTFA,ASCL1,RGS9,CDK5R1,WASF1,CD81,DCLK1,DLGAP3,QKI,CNR1,CLOCK,SLITRK5,DLG4,DRD1,DSCAM,EBF1,ENO2,FOXG1,VTI1B,PPARGC1A,GRIN1,ZIC5,LIG4,MAPT,PPM1L,JAKMIP1,RELN,LRRK2,RXRG,ARX,FUZ,SNCB,SNCA,SOX1,MYCBP2,SPP1,VPS13A,CNTN2,TMEM163,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0003484 abnormal channel response 1.61E-06 1.28E-02 1.12E-04 1.07E-03 22 38 "KCNT1,HCN2,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,DPP6,KCNMB2,FGF12,FGF14,ARPP21,GNAO1,IL6ST,KCNA2,KCND2,KCNK3,KCNMA1,NALCN,PTPRE,KCNIP3,SLC8A3,KCNT2" Mouse Phenotype MP:0000819 abnormal olfactory bulb morphology 1.83E-06 1.46E-02 1.27E-04 1.21E-03 65 173 "MRTFA,ASCL1,NUMB,NRP2,CDK5R1,CDK5R2,PTBP2,NUMBL,LHX2,CNGA3,OLIG1,DSCAM,EDIL3,EFNA2,EFNA3,EGFR,EMX2,ENO2,APC2,FOXG1,TBR1,FYN,GAD1,KIRREL3,CIT,DHX35,IGF1,TUBB2B,LAMA2,NCAM1,NCAM2,NEK1,HCN1,PAX6,POU3F2,HYDIN,RELN,FEZF2,RGS4,RIC8B,SETD5,ROBO2,RPL38,SALL1,ARX,CCDC88A,CDK5RAP2,SOX1,SOX10,SOX11,SP2,NMNAT2,ZNF423,ATP11A,AGTPBP1,ZEB1,RPGRIP1L,NR2E1,TP53BP2,TRIO,VLDLR,ZIC2,MAP3K12,LRP8,ST8SIA2" Mouse Phenotype MP:0002061 abnormal aggression-related behavior 2.03E-06 1.62E-02 1.39E-04 1.33E-03 41 94 "SYN3,ADORA2A,PTCHD1,LRRC7,APBA2,BBS2,CACNA1B,CAMK2A,DLGAP2,CLU,ARHGAP32,EN2,GAD2,KIRREL3,GRIA1,GRIA2,GRIN1,HNMT,LAMA2,LSAMP,MAG,MAOB,MAP6,NOS1,NTRK2,OPHN1,OXTR,HYDIN,RGS4,RORB,ARX,SOX1,SYN1,SYN2,TACR1,ZEB1,CRTC1,NR2E1,TSN,ZIC2,PAK5" Mouse Phenotype MP:0009142 decreased prepulse inhibition 2.11E-06 1.68E-02 1.43E-04 1.36E-03 56 143 "LRFN2,MTA3,LRRC7,ARRB1,ASPA,TMEM108,ATP1A3,ATP2A2,KALRN,CCK,NRXN1,ZNF521,PLEKHM1,SRGAP3,OLIG1,SLC12A6,EDNRA,ENO2,ERBB4,ADGRV1,EZH1,CLVS1,FABP7,FOXO3,GABRA3,GABRA5,GAD2,DISC1,STARD10,ATF7,GRIA4,GRIN1,GRM8,IGSF21,FRMD5,ACOT7,KCNQ2,MAG,MAP6,MAT2A,NRCAM,NTRK2,PCDH9,TMOD2,ZDHHC8,ELMOD1,SLC6A1,CCDC88A,SNAP25,NCDN,PLCB1,TCF4,ZIC2,ANKS1B,TMEM163,FZD3" Mouse Phenotype MP:0012315 impaired learning 2.12E-06 1.69E-02 1.43E-04 1.36E-03 40 91 "SYN3,ADCY8,SLC12A5,PTCHD1,ADRA1B,APP,ATP1A3,CACNA1B,KALRN,CAMK2A,CHRNB2,ARHGAP32,SRGAP3,EML1,ENO2,FGF14,CAMKK2,TBR1,GABBR1,GABRA1,DISC1,GRIA2,GRIN1,RASGRF1,RYR3,ARX,SLC6A8,CCDC88A,TET1,SORCS3,KIF21B,SP4,CLSTN2,SYN1,SYT4,DDHD2,WWC1,TCF4,TMEM163,PAK5" Mouse Phenotype MP:0013189 abnormal exploration in a new environment 2.13E-06 1.70E-02 1.43E-04 1.36E-03 70 191 "ADORA2A,ADRA1B,PLA2G6,ALS2,APP,CHRD,ATP1A1,ATP1A3,STX16,BCL7A,CHRNA4,CNR1,MAGED1,CLOCK,ERC2,BRINP1,SIRPA,OLIG1,SLC12A6,DYRK1A,ERCC2,FGF14,JPH4,DISC1,CPLX2,GRIA1,GRIA2,GRIA4,GRIN1,GRM1,GRM8,HSD17B1,HTR5A,LRRTM1,KCNC1,KCNJ11,L1CAM,LSAMP,MAOB,NPY,OPHN1,PDE4B,PDE1B,ZDHHC8,SERPINI1,SH3KBP1,PKIA,RGS7,RORB,ATXN1,ARX,SP4,NPAS3,SSTR2,ARHGEF9,TAF6,WSCD1,DMXL2,CRTC1,SLC44A1,NR2E1,ZNF142,GDPD5,NAV2,TMEM163,SLC17A6,PAK5,AAAS,ST8SIA2,JPH3" Mouse Phenotype MP:0001402 hypoactivity 2.18E-06 1.74E-02 1.45E-04 1.39E-03 156 511 "ADCY5,SLITRK1,ALK,ANK3,CNTNAP1,APBA2,ALS2,APP,ARNTL,ASPA,CCAR2,ATM,ATP1A3,KIF1A,RGS9,HCN2,BCS1L,CACNA1G,FOXK1,CACNA1A,CACNB4,HAP1,BRSK2,CD81,CDO1,CHN1,PLAA,QKI,MAGED1,CRY2,CTH,SRGAP3,DLG4,DMD,SHANK1,DRD1,EFNA2,EFNA3,COPS4,BSCL2,EML1,EN2,RCAN2,SEZ6,PIPOX,PPP1R1B,FECH,FOXO3,FLNC,NBEA,PDLIM5,FAM49B,GAA,GABBR1,GABRG2,JPH4,STARD10,CPLX2,GATM,GCNT2,GNAS,GPT2,GPR37,GRIA2,GRIN1,GRIN2D,NR3C1,GRM1,GRM7,GSTM5,PSIP1,ATG4C,HRH3,ACOT7,SYNPO,HNMT,NEGR1,SMAP1,LRRTM1,ITPKB,L1CAM,LAMP2,MAG,NAT8L,MBP,MOG,NOS1,NPY,NTRK2,OGG1,PDYN,NLGN3,PLCB2,FTO,PLP1,PMP22,MAGEL2,FA2H,PRKAB2,EPDR1,HYDIN,PROX1,RELN,PEX2,ARID4A,KHDRBS2,RET,RGS7,RPE65,ATXN1,ATXN7,SCN8A,SH3GL2,ARX,CPEB3,SLC1A3,SLC4A3,PREX2,SLC6A1,SLC6A8,CCDC88A,SNAP25,SNCA,KIF13A,BEX1,NFASC,SSTR1,SSTR2,STAU1,VPS13A,SYPL1,TCF7L2,ZEB1,ATP13A2,DICER1,SIRT1,CHST8,ZNF106,ENHO,TK2,TNFRSF1B,SEZ6L,RASD2,TSC1,UBE3A,UGT8,VIPR2,LMF1,ZIC1,ZIC2,TMEM163,PAK5,GJC2,AAAS,IFT88,JPH3" Mouse Phenotype MP:0008946 abnormal neuron number 2.20E-06 1.76E-02 1.45E-04 1.39E-03 166 550 "DSCAML1,UNC5A,ADRB2,KIDINS220,SEMA6A,BCAR3,ANK3,APAF1,GAS7,ALS2,PRX,ASCL1,NUMB,ATP2B2,CACNA1G,CACNA1A,CACNA1D,CACNB2,PTBP2,CDH2,NOG,CRLF1,NUMBL,CACNA2D2,CHM,CHRNA4,CLCN3,CNGA3,CNTFR,WHRN,SLC4A7,ZNF521,CP,CRY2,CSF1,PLXNA4,RIMS2,CX3CR1,BRINP1,DCTN1,GSDME,OLIG1,DSCAM,DNM1L,EDIL3,HEYL,EGFR,EGR3,C8orf37,EMX2,EN2,OLIG2,ENO2,GPHN,ERBB2,ETV1,EYA1,FGF13,FGF14,FGFR1,FGFR3,FOXG1,SMC2,FYN,GABRA1,ATP8A2,SRRM4,GFRA1,PPARGC1A,GLI2,GRIA2,GRM7,GUCY1A1,ACOT7,IGF1,RBPJ,HES5,INSM1,KIF5C,KIT,LAMA2,LIFR,MAPT,MDM4,MITF,AFDN,GIT1,MYCN,MYO6,MYO7A,NDP,RCOR2,NEFH,NEUROD1,NHLH1,NKX2-2,NTRK2,NTRK3,OPA1,PAX6,PCDH9,PLXNB1,ANKRD16,POU3F2,RELN,KLK6,PTCH1,RET,RFX3,KIF7,RLBP1,RIC8B,RORB,RPE65,FBXW7,LRRK2,RXRA,ATXN1,ATXN7,SCN8A,ARX,SLC1A2,SLC1A3,SIRT2,CCDC88A,SLC12A2,SMARCC2,IFT122,SNCA,SOX2,TNIK,SOX10,SOX11,NMNAT2,SPP1,ZNF423,KIF1B,SMOC1,STXBP1,SYNE2,SEMA4A,AGTPBP1,ATMIN,CUX2,TRIM2,SLC19A3,CRB1,ZNF106,HHIP,HEY1,TP53BP2,RBFOX2,CDK20,NR2C2,TRPC3,TSC1,TUB,ZIC2,CRB2,MAP3K12,LRP8,GDPD5,TUBA1A,PDSS2,VANGL2,ST8SIA2" Mouse Phenotype MP:0000823 abnormal lateral ventricle morphology 2.34E-06 1.87E-02 1.53E-04 1.47E-03 67 181 "APAF1,ARHGAP5,ASPA,NUMB,BBS2,CDK5R1,WASF1,PTBP2,DCLK1,NUMBL,CLCN3,CSF1R,TRAPPC9,CDON,DRD1,PDCD6IP,DSCAM,E2F5,EMX2,PRMT5,FOXG1,VTI1B,AK8,CHL1,HSF2,ZIC5,KCNJ10,L1CAM,MDM4,PPM1L,MSI1,BLOC1S2,MYO9A,NEK1,NFIA,NFIX,NRDC,OPA1,OPHN1,PKD1,PLXNB1,MBOAT7,POU3F2,HYDIN,RGS4,ZC3H14,ATAT1,ATXN1,TET1,SOX2,MYCBP2,ZNF423,SPTAN1,NPAS3,MAPK8IP3,CNTN2,AP4E1,NR2E1,TP53BP2,TSC1,VLDLR,ZIC2,MAP3K12,LRP8,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0000913 abnormal brain development 2.39E-06 1.91E-02 1.55E-04 1.49E-03 234 821 "ABR,ADD1,AXIN2,FZD9,PCDH19,NME5,CC2D2A,MRTFA,AMT,APAF1,APBB1,APBB2,APC,PRX,ASCL1,CHRD,NUMB,ASTN1,DYNLL1,NRP2,BMP7,CDK5R1,WASF1,CDK5R2,CACNA1A,CACNB2,PTBP2,BRSK2,CDH2,DCLK1,LGI1,NOG,NUMBL,CACNA2D2,GPR37L1,ADGRG1,CHN2,NDST3,LHX2,HECTD1,CNN3,COX4I1,ZNF521,NCOR2,CSF1,CSF1R,PYGO1,BOC,HDAC4,ZEB2,SRGAP3,KIF19,DLG3,OLIG1,MED12,CDON,DNM2,ABI1,PDCD6IP,DSCAM,DNM1L,E2F5,EDIL3,EFNA3,CELSR3,APH1A,EGFR,EML1,EMX2,EN2,OLIG2,COQ7,CEND1,F3,ZIC4,DLC1,ZMYND10,PRMT5,FGFR1,FOXG1,EVL,TMEM107,AK8,ATP2C1,TBR1,BRSK1,GALC,DNER,GBX2,GDF1,GFAP,GLDC,GLI2,KDM2B,GPT2,CECR2,KIF3A,SYNPO,HMX1,DHX35,ZIC5,LRRCC1,HES5,IL6ST,TUBB2B,ITGAV,KCNA1,KIT,L1CAM,LAMA2,LIG4,MBD1,MDM4,KITLG,AFDN,MSI1,BLOC1S2,MTTP,MYCN,MYO9A,NEK1,NEUROD1,NF1,NFIA,NFIX,NKX2-2,NODAL,NRCAM,HCN1,NTRK2,ODF2,OPA1,OPHN1,PAX6,PDGFRA,ENPP2,PDPK1,SERPINE2,PIK3C2A,PKD1,PLP1,PLXNB1,PSAT1,MBOAT7,POU3F2,MED1,PRKACB,CEP41,MAPK7,MAPK8,MAPK9,HYDIN,RELN,LAMA1,PTCH1,PTK2,PEX2,PEX5,CCDC40,FEZF2,KHDRBS2,FIGN,RFX4,RGS4,KIF7,TMEM100,FBXW7,RPL38,WLS,RXRA,SALL1,SCN8A,KIF27,ARX,FUZ,AMBRA1,CCDC88A,TET1,SMARCA4,CDK5RAP2,IFT122,PALLD,SOX1,SOX2,SOX11,SP2,MYCBP2,ZNF423,SPTAN1,NPAS3,MAPK8IP3,TTBK2,JMJD6,COBL,ATP11A,MLST8,CNTN2,ATMIN,TCF4,ZEB1,RPGRIP1L,TCF12,USP22,TEK,SIRT1,GPR161,HHIP,THRA,TIAM1,TIE1,NR2E1,PARD3,TP53BP2,RBFOX2,CDK20,TRIO,TSC1,HIRA,VAV2,TOM1L2,VLDLR,ZBTB14,ZIC1,ZIC2,ZIC3,CRB2,SPHK2,LRP8,RGMA,TMEM163,PDSS2,VANGL2,IFT88,ST8SIA2" Mouse Phenotype MP:0003871 abnormal myelin sheath morphology 2.43E-06 1.94E-02 1.57E-04 1.50E-03 36 79 "PLA2G6,CNTNAP1,CANX,CD86,QKI,OLIG1,SLC12A6,DRP2,ERBB2,GABBR1,GALC,GJB1,GPM6B,MAG,MBP,PPM1L,NCAM1,NFE2L2,NRCAM,NRDC,NTRK2,CLDN11,PLP1,PMP2,PMP22,FA2H,SH3TC2,ERBIN,SEPT8,MLC1,FGD4,TLR4,HEPACAM,LGI4,ZNF24,GAN" Mouse Phenotype MP:0001970 abnormal pain threshold 2.68E-06 2.14E-02 1.71E-04 1.64E-03 86 249 "ADCY8,SLC12A5,ADORA1,ADORA2A,KCNT1,PRX,MADD,ARRB2,ASPA,ATP1A3,KIF1A,BBS2,HCN2,CDK5R1,CACNA1A,CACNA1B,BRSK2,CCKBR,P2RX6,ADGRG1,ASIC3,CHRNA4,CHRNB2,TPP1,CNR1,WHRN,CNTNAP2,FRMPD4,HDAC4,GIT2,DLG4,SLC12A6,EDNRB,KMT5B,SEMA6C,FLNC,BRSK1,GABBR1,GABRA2,GABRA4,GNAO1,PRLHR,GRIA1,GRIA2,GRIA4,GRIK1,GRIK5,GRM5,GRM7,MAP4K5,KCNA1,KCNA6,KCND2,NBL1,HCN1,OPRL1,P2RX7,PCSK2,PIRT,PDYN,PENK,RETREG1,PRKAR1B,PRKCG,PTPRG,PTPRZ1,KCNIP3,S100B,ARX,SLC6A9,SOX10,MYCBP2,SPP1,ERBIN,TAC1,TACR1,ZNF106,TLR4,NR2C2,NTSR2,TSC1,UCHL1,KCNT2,NAV2,SLC17A6,RNF170" Mouse Phenotype MP:0004262 abnormal physical strength 3.39E-06 2.71E-02 2.15E-04 2.06E-03 152 499 "SYN3,ACHE,SLITRK1,PLA2G6,ADGRF5,LTBP4,UNC79,ALK,CNTNAP1,GAS7,ALS2,APP,SPTBN4,ARHGDIA,ARRB2,ASPA,ATP2B2,RGS9,CDK5R1,SYNJ1,WASF1,CDK5R2,FOXK1,CACNA1A,CACNA1B,CAMK2B,CD86,PLAA,NRXN1,TPP1,ABCG2,QKI,TMEM184B,CNTN1,GAL3ST1,NECTIN3,PREPL,CRYM,CX3CR1,DBI,ELMO1,DLG4,DMD,CDON,SLC12A6,DRD1,DTNA,DTNB,USH1C,EEF1A2,MBNL2,EIF4G2,EN2,OLIG2,DNAJC27,EFEMP1,FKTN,FGF12,FGF14,MAD2L2,FHL1,CAP2,FLNC,FYB1,GAA,GABBR1,GAD1,GALC,SALL3,GATM,USP19,PPARGC1A,GNAS,GRIA2,GRIA4,GRM1,GRM7,RNF165,BVES,PSIP1,FRMD5,VSIG4,NEGR1,HSP90AA1,SMAP1,ITGAV,KCNA2,KCNJ10,L1CAM,LAMA2,SMAD9,MAPT,MBNL1,CD200,NOVA1,NRCAM,NRDC,OGDH,CLDN11,PLP1,PMP22,MAGEL2,PTH1R,PYGM,SH3TC2,RET,SETD5,RYR1,SCN8A,ELMOD1,SH3GL2,ARX,CCDC92,WDR37,SLC2A5,WDR47,SLC6A8,SIRT2,SLC12A2,SLC20A2,SNCA,MBD5,SNRPN,SOX1,ZHX3,SPP1,MLC1,FGD4,AGTPBP1,IQCE,SYNE1,AKNA,AP4E1,ZNF106,GALNT17,THRA,NACC2,TK2,CBX5,LRRC8A,TNFRSF1B,TNS1,SSBP2,UCHL1,FRRS1L,ELFN1,EPM2A,UBE3B,PAK5,RNF170,FXR1,GAN" Mouse Phenotype MP:0005403 abnormal nerve conduction 3.67E-06 2.93E-02 2.31E-04 2.20E-03 34 74 "ABCD2,CNTNAP1,PRX,MTMR2,CACNB4,CANX,CD86,SLC12A6,ERBB2,ETV1,NKX6-2,GJB1,LAMA2,STMN1,MBP,NRCAM,NALCN,PLEC,PLP1,PMP2,PMP22,SH3TC2,GLDN,SCN8A,SLC1A3,SLC1A6,SIRT2,SOX10,NFASC,ERBIN,SEPT8,FGD4,TNR,UGT8" Mouse Phenotype MP:0000948 nonconvulsive seizures 3.98E-06 3.18E-02 2.46E-04 2.35E-03 24 45 "ATP1A3,HCN2,CACNA1G,CACNA1A,LGI1,CACNA2D2,HDAC4,ELAVL3,CACNG2,GABBR1,GABRA1,GABRB3,GABRG2,KCNMB4,GNAO1,GRIA4,HLF,MBP,SLC10A4,SCN8A,ARX,SOX2,UBE3A,CELF4" Mouse Phenotype MP:0001900 impaired synaptic plasticity 3.98E-06 3.18E-02 2.46E-04 2.35E-03 24 45 "ADD2,KSR1,CDK5R1,CAMK2A,CLCN3,PICK1,DBN1,MBNL2,DPYSL4,CPLX2,CPLX1,GRIA1,GRIA2,GRIN1,MAP6,NTRK2,NLGN3,RASGRF1,STX1A,SYP,VLDLR,CLIP2,ELFN1,ANKS1B" Mouse Phenotype MP:0002184 abnormal innervation 4.04E-06 3.23E-02 2.48E-04 2.37E-03 84 244 "SORCS2,ALCAM,ALS2,ATP2B2,NRP2,CDK5R1,CA8,BRSK2,CBLN1,CHN1,VAX2,CLIP3,LRIG1,PLXNA4,RIMS2,BOC,DCC,DLG3,DLG4,SEZ6L2,EEF1A2,EFNA2,EFNB3,CELSR3,EGFR,EGR3,OLIG2,SEZ6,EPHA5,EPHB1,ERBB2,ERBB4,ETV1,CACNG2,FGFR3,VTI1B,POMT1,TBR1,GABRA5,CHL1,GABRB3,SRRM4,DNER,GBX2,GFRA1,GRIN1,GRM7,RNF165,HMX1,TLX1,IGF1,KCNMA1,L1CAM,SMAD9,MAPT,MYO7A,NEUROD1,NOS1,NPR2,NPTX1,NPTX2,NRCAM,NTRK2,NTRK3,RELN,PTK2,PTPN13,RET,ROBO1,ROBO2,SCN8A,SIRT2,CPEB4,SOX11,NMNAT2,MYCBP2,ROBO3,CNTN2,ZEB1,SEZ6L,WBP2,VAV2,KAT6A,GAN" Mouse Phenotype MP:0002885 abnormal AMPA-mediated synaptic currents 4.30E-06 3.43E-02 2.62E-04 2.51E-03 21 37 "GPR158,CNIH2,KALRN,SHISA7,LGI1,NRXN1,NRXN2,AKAP5,CNIH3,DLG4,CACNG7,CACNG2,GRIA1,GRIA2,GRIA4,GRIN1,LRRTM1,NLGN3,STX1B,ARC,SLC17A6" Mouse Phenotype MP:0009939 abnormal hippocampus neuron morphology 4.70E-06 3.75E-02 2.84E-04 2.72E-03 50 126 "MRTFA,ANK3,CADPS,TMEM108,ATP1A3,NRP2,CDK5R1,KALRN,CAMK2A,CD81,CLCN3,ZNF521,CRMP1,CSF1,CST3,CTNND1,DGKB,DLG4,SHANK1,SLC12A6,EFNA3,ABI2,APC2,CACNG2,FGF14,FOXG1,DPYSL4,STAMBP,FYN,GABRB3,GFAP,DCLK2,GPT2,GRIA2,HPCA,MAPT,AFDN,NEUROD1,ABCB1,PROX1,CPEB3,SLC1A2,SOX2,PLCB1,SYN1,TSC1,TSC2,TUBA1A,EPM2A,ST8SIA2" Mouse Phenotype MP:0002799 abnormal passive avoidance behavior 5.09E-06 4.06E-02 3.05E-04 2.92E-03 27 54 "ADCY8,ADRA1B,DOC2A,APBB1,APP,ATP1A3,KALRN,CHRNB2,LYPD1,SRGAP3,DRD1,FYN,GABBR1,GABRA1,JPH4,DISC1,MCHR1,GRIN1,OPRL1,MAPK3,RYR3,ARX,SP4,EPM2A,PAK5,ST8SIA2,JPH3" Mouse Phenotype MP:0003216 absence seizures 5.15E-06 4.11E-02 3.07E-04 2.93E-03 22 40 "ATP1A3,HCN2,CACNA1G,CACNA1A,LGI1,CACNA2D2,HDAC4,ELAVL3,CACNG2,GABBR1,GABRA1,GABRB3,GABRG2,GNAO1,GRIA4,HLF,MBP,SLC10A4,SCN8A,ARX,UBE3A,CELF4" Mouse Phenotype MP:0000877 abnormal Purkinje cell morphology 6.09E-06 4.86E-02 3.59E-04 3.43E-03 82 239 "SLC12A5,SPARCL1,ABCD2,ANK1,ANK3,ALS2,APP,NCOA1,NUMB,ATM,ATP2B2,BCL2L2,FGF17,CDK5R1,SGCE,CACNA1G,CACNA1A,CALB1,AIFM1,CACNA2D2,GPR37L1,SLIT2,PLAA,TPP1,QKI,CNTN1,CP,DNM1,DNM1L,EDIL3,EEF1A2,EGFR,ERCC2,APC2,CEND1,AP4B1,GABRA1,B4GALNT1,IP6K3,GLRB,MAP2,MDM4,AFF1,MYCN,MYO5A,NEUROD1,NTRK2,PAX6,ANKRD16,FA2H,RELN,LAMA1,PEX2,ROBO2,FBXW7,ACER3,ATXN1,ATXN2,ATXN7,SCN8A,SLC1A3,PREX2,ZNF423,NFASC,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,THRA,ENHO,RBFOX2,PRMT8,TRPC3,TSC1,TSC2,UGT8,DPYSL5,LRP8,PDSS2,EPM2A,GJC2" Mouse Phenotype MP:0001360 abnormal social investigation 6.12E-06 4.89E-02 3.59E-04 3.43E-03 50 127 "SYN3,LRFN2,APBA2,NUMB,DLGAP2,DLGAP1,NUMBL,CHRNB2,NRXN2,MAGED1,ZNF521,CNTNAP2,ARHGAP32,BRINP1,SRGAP3,DLG4,EFNA2,EFNA3,EN2,NBEA,TBR1,GABRB3,DISC1,GNAO1,MCHR1,GRIA1,GRIA4,GRIN1,DOCK7,LRRTM1,L1CAM,NAT8L,MAP6,NRCAM,OXTR,PCDH9,NLGN3,RELN,ARX,SHANK2,MBD5,NPAS3,STX1A,VPS13A,SYN1,SYN2,CRTC1,TRPM2,TSC1,TSC2" Mouse Phenotype MP:0000951 sporadic seizures 6.33E-06 5.06E-02 3.69E-04 3.53E-03 20 35 "KCNAB2,NUMB,CACNA1A,CAMK2A,NUMBL,GABBR1,CPLX1,GJB1,GNAO1,KCNC2,KIF5A,MBP,NEUROD1,NEUROD2,NPY,ARX,SOX10,CNTN2,TSC1,GJC2" Mouse Phenotype MP:0001523 impaired righting response 7.23E-06 5.77E-02 4.15E-04 3.97E-03 51 131 "ACHE,PKP4,APP,ARNTL,ATP2A2,ATP2B2,CACNA1I,BSN,CACNA1A,CACNB4,CFL2,CHN1,WHRN,PREPL,HAPLN1,DRD1,USH1C,EDIL3,EFNB3,EN2,CACNG2,ZIC4,SUCO,GABRG2,GALC,B4GALNT1,SALL3,GLI2,GLRB,GNAO1,GNAS,GRIN1,GRM1,GRM7,HSD17B1,ATCAY,KCNJ10,MOG,MYO5A,MYO7A,NTRK2,PMP22,RELN,EPHA10,SHANK2,SOX2,VAMP1,LGI4,ZIC1,SLC30A4,PCDH15" Mouse Phenotype MP:0005405 axon degeneration 7.23E-06 5.77E-02 4.15E-04 3.97E-03 41 98 "PLA2G6,ABCD2,ALS2,SPTBN4,KIF1A,MTMR2,CACNA2D2,TMEM184B,CSF1R,CYBB,SLC12A6,CHL1,GALC,NKX6-2,ATP8A2,GJB1,GPM6B,ITGA7,ITGAV,KCNJ10,KIF5A,KLC1,STMN1,MAG,MBP,NCAM1,NEFH,NF1,OPA1,PLP1,PMP22,SCN8A,SNCA,NMNAT2,STXBP1,MTCL1,ZNF106,UCHL1,REEP1,EPM2A,GJC2" Mouse Phenotype MP:0002917 decreased synaptic depression 7.38E-06 5.89E-02 4.21E-04 4.03E-03 13 18 "ADORA1,BSN,CHRM1,CHRM4,CNR1,SV2B,SV2A,PCDH17,PDE4B,PACSIN1,PRKACB,STX1A,SYN2" Mouse Phenotype MP:0000934 abnormal telencephalon development 7.71E-06 6.16E-02 4.37E-04 4.18E-03 62 169 "APAF1,APBB1,APBB2,APC,PRX,ASCL1,NUMB,CDK5R1,CDK5R2,PTBP2,BRSK2,CDH2,NUMBL,ADGRG1,LHX2,NCOR2,EDIL3,CELSR3,APH1A,EML1,EMX2,PRMT5,FOXG1,EVL,BRSK1,GBX2,GLI2,SYNPO,ZIC5,HES5,IL6ST,TUBB2B,KIT,AFDN,BLOC1S2,MYCN,NTRK2,PAX6,PLXNB1,POU3F2,MED1,RELN,PTCH1,FEZF2,FBXW7,ARX,AMBRA1,SOX11,SP2,MYCBP2,SPTAN1,MAPK8IP3,MLST8,CNTN2,USP22,NR2E1,PARD3,TP53BP2,VLDLR,ZIC2,LRP8,TMEM163" Mouse Phenotype MP:0002862 altered righting response 9.19E-06 7.33E-02 5.16E-04 4.94E-03 56 149 "ACHE,PKP4,APP,ARNTL,ATP2A2,ATP2B2,CACNA1I,BSN,CACNA1A,CACNB4,CFL2,CHN1,WHRN,PREPL,HAPLN1,CYBB,DRD1,USH1C,EDIL3,EFNB3,EML1,EN2,EPS8,CACNG2,ZIC4,SUCO,GABRB3,GABRG2,GALC,B4GALNT1,SALL3,GLI2,GLRB,GNAO1,GNAS,GRIN1,GRM1,GRM7,HSD17B1,ATCAY,KCNJ10,MOG,MYO5A,MYO7A,NTRK2,NLGN3,PMP22,RELN,EPHA10,SHANK2,SOX2,VAMP1,LGI4,ZIC1,SLC30A4,PCDH15" Mouse Phenotype MP:0001525 impaired balance 1.02E-05 8.12E-02 5.68E-04 5.43E-03 55 146 "ABR,ABCD2,ANK1,CNTNAP1,SPTBN4,ATP2B2,KIF1A,HCN2,SGCE,WASF1,CACNA1A,CAMK2B,PLAA,BLOC1S6,DLG4,DRD1,DSCAM,USH1C,ERCC2,PRMT5,FGF14,SRRM4,GLI2,GNAS,GRIN2C,GRM1,GRM7,KCNA1,KCNC1,KCNJ10,MAPT,AFF1,MYO5A,MYO6,MYO7A,NEUROD1,NOS1,PAH,TMIE,RELN,PEX2,PRRT2,SCN8A,ARX,SLC12A2,NFASC,DDHD2,ROBO3,TRPC3,VLDLR,LRP8,PCDH15,PDSS2,EPM2A,VANGL2" Mouse Phenotype MP:0009435 abnormal miniature inhibitory postsynaptic currents 1.07E-05 8.53E-02 5.93E-04 5.67E-03 24 47 "ATP1A3,BAIAP3,CACNA1B,CACNA2D2,PLAA,ARHGAP32,FGF13,NBEA,GABRA1,GABRA2,GABRB1,GABRG2,IGSF21,KCNA2,KIF5A,GIT1,NLGN3,PACSIN1,SLC26A11,STX1B,SLITRK3,NLGN1,LHFPL4,STX1A" Mouse Phenotype MP:0012676 dilated brain ventricles 1.12E-05 8.96E-02 6.18E-04 5.91E-03 39 93 "ARHGAP5,CDK5R1,NCOR1,DSCAM,E2F5,EMX2,ZMYND10,AK8,HSF2,ZIC5,KCNJ10,L1CAM,MDM4,MSI1,MYO9A,NEK1,NFIA,NFIX,OPA1,OPHN1,PKD1,MBOAT7,HYDIN,ATAT1,ATXN1,FUZ,MYCBP2,ZNF423,SPTAN1,MAPK8IP3,RPGRIP1L,NR2E1,TP53BP2,CLIP2,CRB2,SPHK2,MAP3K12,FZD3,ST8SIA2" Mouse Phenotype MP:0000937 abnormal motor neuron morphology 1.16E-05 9.27E-02 6.35E-04 6.07E-03 66 185 "UNC5A,KIDINS220,ALCAM,APAF1,GAS7,ALS2,CDK5R1,CDK5R2,CACNB4,CRLF1,CACNA2D2,CHN1,CNTFR,CP,CLIP3,RIMS2,DCTN1,OLIG1,EEF1A2,EFNB3,EGR3,OLIG2,GPHN,ERBB2,ERBB4,CACNG2,FGFR1,ATP8A2,SRRM4,GBX2,GFRA1,GLI2,GRIA2,GRM7,RNF165,ATCAY,IGF1,KIF5A,KIF5C,LIFR,SMAD9,MAPT,NEFH,NKX2-2,NOS1,NTRK2,PTCH1,RET,RFX4,KIF7,SCN8A,FUZ,SLC1A2,CPEB4,IFT122,SOX2,SOX10,NMNAT2,MYCBP2,ZNF106,UCHL1,REEP1,MAP3K12,LRP8,GDPD5,GAN" Mouse Phenotype MP:0006007 abnormal basal ganglion morphology 1.19E-05 9.51E-02 6.47E-04 6.19E-03 51 133 "MRTFA,ASCL1,BBS2,RGS9,CDK5R1,WASF1,CD81,DCLK1,LHX2,DLGAP3,QKI,CNR1,CLOCK,SLITRK5,DLG4,DRD1,DSCAM,EBF1,CELSR3,ENO2,TUBB3,FOXG1,VTI1B,PPARGC1A,GPR37,GRIN1,ZIC5,TUBB2B,LIG4,MAPT,PPM1L,JAKMIP1,RELN,RFX4,LRRK2,RXRG,ARX,FUZ,SLC20A2,SNCB,SNCA,SOX1,MYCBP2,SPP1,VPS13A,CNTN2,ZIC3,TMEM163,FZD3,VANGL2,ST8SIA2" Mouse Phenotype MP:0000921 demyelination 1.21E-05 9.65E-02 6.49E-04 6.21E-03 42 103 "APP,ASPA,CANX,CD86,TPP1,QKI,CP,CSF1,TENM4,CSF1R,CX3CR1,SLC12A6,EEF1A2,ERBB2,FDFT1,GALC,ATP8A2,GJB1,GPM6B,ITGAV,LAMA2,STMN1,MAG,MBP,MOG,ADAM22,NRCAM,NTRK2,OPA1,PLP1,PMP22,FA2H,PTPRE,SH3TC2,SOX10,SEPT8,FGD4,TNFRSF1B,MGAT5B,LGI4,REEP1,GJC2" Mouse Phenotype MP:0003461 abnormal response to novel object 1.21E-05 9.68E-02 6.49E-04 6.21E-03 30 65 "ADRA1B,LRRC7,APBA2,CHRD,ATP1A3,WASF1,NRXN2,QKI,ARHGEF6,CNR1,NCOR1,DGKB,SNAP91,SRGAP3,EFNA3,CHL1,GABRB3,DISC1,GRIA2,NAT8L,NTRK2,SLC6A1,SLC6A8,MBD5,NPAS3,STX1A,ATP13A2,TSC2,TUBA1A,SLC4A10" Mouse Phenotype MP:0001513 limb grasping 1.24E-05 9.90E-02 6.60E-04 6.31E-03 85 254 "SLITRK1,LRRC7,PRX,SPTBN4,ASPA,ATP1A3,ATP2B2,RGS9,MTMR2,CACNA1A,CACNA2D2,PLAA,PPT2,NIPBL,AKAP12,ARHGAP32,DCTN1,SNAP91,DMTF1,SLC12A6,DRD1,ATN1,USH1C,EDIL3,ELAVL4,OLIG2,ERCC2,FGF14,STAMBP,GABRB3,GABRG2,GAD1,JPH4,ATP8A2,CPLX2,PPARGC1A,GLRB,GRM1,GRM7,PSIP1,KCNA2,KCNJ3,LAMA2,MAPT,MBP,PPM1L,DBNL,NDUFA5,NFIX,NPR2,NRCAM,NRDC,NTRK3,OPA1,PMP2,PMP22,LAMA1,PEX2,SH3TC2,RORB,RPE65,ACER3,SATB1,ATXN1,ATXN7,SCN8A,PREX2,WDR47,SHANK2,NPAS3,EPB41L3,ATP13A2,AP4E1,ZNF106,PRMT8,TRIO,TSC1,UBE3A,UCHL1,FRRS1L,WNT7A,NDRG4,DPYSL5,CERS6,JPH3" Mouse Phenotype MP:0005445 abnormal neurotransmitter secretion 1.36E-05 1.08E-01 7.17E-04 6.86E-03 36 84 "DOC2A,CASK,CHRD,ST3GAL5,CACNA1A,CACNA2D2,CHRNA4,RAB3C,NRXN1,NRXN2,SLC32A1,DLG4,EEF1A2,EN2,CPLX2,CPLX1,GFRA1,PCLO,HRH3,NOS1,MAPK9,RAB3A,RET,LRRK2,SLC1A3,SLC6A1,RAB3GAP1,SNAP25,SNCA,SSTR1,SSTR2,SYN1,SYT1,PRMT8,UCHL1,SLC17A6" Mouse Phenotype MP:0002888 abnormal NMDA-mediated synaptic currents 1.37E-05 1.09E-01 7.18E-04 6.86E-03 18 31 "RGS9,WASF1,LGI1,DLGAP3,NRXN1,NRXN2,DAPK1,DLG4,EPS8,FABP7,GRIK4,GRIN1,GRIN2C,SERPINE2,CLSTN1,SLC6A9,TCF4,TMEM163" Mouse Phenotype MP:0011085 "postnatal lethality, complete penetrance" 1.45E-05 1.16E-01 7.56E-04 7.23E-03 189 658 "ACHE,ADAR,SLC12A5,PCDH10,UNC79,MRTFA,AMPD2,AMPD3,OGT,ANK1,ANK3,CNTNAP1,APAF1,APC,APP,SLC4A4,RIPK1,KIF1A,ADAM23,BMP7,SYNJ1,NAE1,MYRF,CACNA1A,HAP1,PTBP2,DCLK1,LGI1,CFL2,CHRNB2,CNTN1,CPS1,CSF1R,CTNND1,HDAC4,MAML1,DBT,MAGI2,SNAP91,SV2B,SV2A,ARNT2,DLX1,DNM1,OLIG1,DRD1,DSCAM,GNE,DNM1L,ABCC9,EDIL3,EDNRB,EGFR,EMX2,OLIG2,SLC43A2,ERBB4,ERCC2,SPEG,F3,PRMT5,FGFR1,SUCO,FOXG1,FOXF2,TBR1,FYN,GABRG2,GAP43,ATP8A2,GCK,PPARGC1A,SPIN1,GLI2,GLUL,LOXL3,GNAS,GRIA2,GRIN1,NR3C1,GRM7,CIT,RNF165,IGF1,RBPJ,KCNA2,KCNJ10,KIF5A,KIT,L1CAM,LAMA2,MAPT,AQP11,MDM4,MEF2C,KITLG,PPM1L,MITF,MMP16,ADAM22,MYH6,MYO5A,MYT1,NEUROD1,NF1,NKX2-2,NOVA1,NOVA2,SLC11A2,NRCAM,NTRK2,NTRK3,PAX6,PBX1,PDGFRA,PKD1,PLEC,PLP1,POU3F2,HYDIN,PROX1,PTCH1,PTHLH,PEX2,PEX5,CCDC40,RET,FIGN,RGS10,ROBO2,GLDN,RPL38,STX1B,SATB1,ATXN1,SCN2A,SCN8A,FNIP1,SOX6,CASC3,ARX,FERMT1,FHOD3,SLC1A2,CCDC88A,SLC14A1,EPC1,SMARCA4,SMARCC2,MBD5,SNRPN,SOX10,SOX11,SP2,SPP1,ZNF423,NFASC,SMOC1,MAPK8IP3,VAMP1,SYT1,CAMTA1,TCF4,TCF12,TF,DICER1,SIRT1,ZFPM2,THRA,TK2,HEY2,RBFOX2,RGMB,TRIO,TSC1,TSC2,VLDLR,LMF1,NSD2,ZIC1,ZIC2,MAP3K12,LRP8,SNX27,SLC17A6,PDSS2,NLRP3,TTC7A,ST8SIA2" Mouse Phenotype MP:0002980 abnormal postural reflex 1.47E-05 1.17E-01 7.57E-04 7.24E-03 58 158 "ACHE,PKP4,APP,ARNTL,ATP2A2,ATP2B2,CACNA1I,BSN,CACNA1A,CACNB4,CFL2,CHN1,WHRN,PREPL,HAPLN1,CYBB,DRD1,USH1C,EDIL3,EFNB3,EML1,EN2,EPS8,CACNG2,ZIC4,SUCO,GABRB3,GABRG2,GALC,B4GALNT1,SALL3,GLI2,GLRB,GNAO1,GNAS,GRIK4,GRIN1,GRM1,GRM7,HSD17B1,ATCAY,KCNJ10,MOG,MYO5A,MYO7A,NTRK2,NLGN3,PMP22,RELN,EPHA10,SHANK2,SOX2,VAMP1,ZEB1,LGI4,ZIC1,SLC30A4,PCDH15" Mouse Phenotype MP:0002919 enhanced paired-pulse facilitation 1.47E-05 1.17E-01 7.57E-04 7.24E-03 22 42 "ADD2,APBA2,CHRD,CACNA1A,RAB3C,SNPH,SIRPA,SNAP91,DLG4,CSPG5,STXBP5,MAPT,MEF2C,PTN,RAB3A,SLC8A2,RAB3GAP1,SNAP25,TNIK,STX1A,SYN1,RIMBP2" Mouse Phenotype MP:0000746 weakness 1.58E-05 1.26E-01 8.06E-04 7.71E-03 53 141 "ACHE,UNC79,CNTNAP1,APP,SPTBN4,ARHGDIA,CDK5R1,SYNJ1,WASF1,CDK5R2,FOXK1,CACNA1A,PLAA,TPP1,QKI,CNTN1,GAL3ST1,NECTIN3,PREPL,DBI,DMD,CDON,SLC12A6,EEF1A2,FKTN,FGF12,FGF14,MAD2L2,GABBR1,GALC,SALL3,GNAS,GRIA2,GRM1,SMAP1,ITGAV,KCNJ10,MAPT,NOVA1,PLP1,RET,SCN8A,ARX,SLC12A2,SNCA,SNRPN,AGTPBP1,SYNE1,AKNA,TK2,LRRC8A,TNS1,GAN" Mouse Phenotype MP:0009750 impaired behavioral response to addictive substance 1.77E-05 1.41E-01 8.92E-04 8.53E-03 25 51 "ADORA2A,ADRA1D,ADRA1B,AQP4,CACNA1B,CCKBR,CD81,CHRNA4,TAOK2,CNR1,GPRASP1,DLG4,DRD1,ENO2,PPP1R1B,PDLIM5,GRIN1,GRM5,OPRL1,PRKCG,RGS4,LRRK2,SLC6A9,TACR1,SLC17A6" Mouse Phenotype MP:0001441 increased grooming behavior 1.77E-05 1.41E-01 8.92E-04 8.53E-03 25 51 "DLGAP1,DLGAP3,NRXN1,QKI,CNTNAP2,SLITRK5,ARHGAP32,DLG4,OLIG1,EFNA2,EFNA3,EN2,NBEA,L1CAM,NAT8L,NEUROD2,NOS1,JAKMIP1,PRRT2,LRRK2,SLC6A8,SHANK2,MBD5,SYN2,TSC1" Mouse Phenotype MP:0008428 abnormal spatial working memory 1.98E-05 1.58E-01 9.94E-04 9.51E-03 35 82 "ADRA1D,APP,TMEM108,KALRN,CAMK2A,DGKB,BRINP1,SRGAP3,DLG4,SHANK1,EDIL3,ENO2,FGF13,CHL1,DISC1,GRIA1,GRIA2,GRIA4,GRIN1,GRM7,LRRTM1,MAPT,NRDC,NTRK2,PDE4B,PTPRZ1,ZC3H14,ATXN1,SLC6A1,SLC6A8,SORCS3,STX1A,WWC1,ZIC2,TUBA1A" Mouse Phenotype MP:0002802 abnormal discrimination learning 2.00E-05 1.60E-01 9.99E-04 9.55E-03 17 29 "SYN3,CACNA1B,NEURL1,ARHGAP32,DLG4,ENO2,CAMKK2,TBR1,GRIA2,GRIN1,NF1,NPTX2,PAH,RASGRF1,TNIK,SYN1,SYT4" Mouse Phenotype MP:0002082 postnatal lethality 2.06E-05 1.64E-01 1.02E-03 9.76E-03 358 1360 "ACADM,ACHE,ADAR,DSCAML1,SLITRK1,ADCYAP1R1,SLC12A5,CDC7,AGT,PCDH10,LTBP4,UNC79,ALK,MRTFA,AMPD2,AMPD3,OGT,ANK1,ANK3,CNTNAP1,APAF1,APBB1,APBB2,APC,APP,CASK,NUMB,SLC4A4,RIPK1,KIF1A,ADAM23,HCN2,NRP2,BMP7,SYNJ1,NAE1,WASF1,MYRF,FOXK1,CA4,CACNA1A,CACNA1B,HAP1,PTBP2,CANX,RUNX1T1,CBS,CBFA2T2,CDC25B,DCLK1,LGI1,CDO1,NUMBL,CACNA2D2,CFL2,CHRNB2,NRXN1,NRXN2,QKI,NIPBL,CNR1,CNTN1,AKAP6,NRG2,ZNF385A,CPS1,CSF1,CSF1R,CTNND1,HDAC4,KIF26A,MAML1,BRINP1,DBT,DNAJC6,HP1BP3,MAGI2,PLPPR4,SNAP91,SV2B,SV2A,KIF19,ARNT2,DLG4,DLX1,DMD,DNM1,OLIG1,CDON,CPEB2,DMTF1,DPH1,DRD1,ATN1,DSCAM,GNE,DTNA,DYRK1A,DNM1L,ABCC9,E2F6,EDIL3,EDN3,EDNRB,HEYL,EFNA3,EGFR,MBNL2,EGR3,PLEKHA1,BSCL2,EMX2,OLIG2,SLC43A2,ERBB2,ERBB4,ERCC2,SPEG,F3,CACNG3,CACNG2,ZIC4,ZMYND10,PRMT5,SEC24B,ACTL6B,FGFR1,FGFR3,SUCO,FOXG1,CAP2,FOXF2,DLL3,TBR1,DOT1L,FYN,GAB1,GABBR1,GABRA1,GABRA2,GABRB3,GABRG2,GALC,GAP43,ATP8A2,GBX2,GCK,GHR,PPARGC1A,GLDC,SPIN1,GLI2,GLRB,GLUL,DCLK2,GNAL,LOXL3,GNAO1,GNAS,GPD2,GRIA2,GRIN1,NR3C1,GRM7,CIT,RNF165,MFSD2A,PSIP1,HMGCR,HP,HSF2,IGF1,ZIC5,RBPJ,IL6ST,ITGAV,KCNA1,KCNA2,KCNJ10,KCNQ2,KIF5A,KIT,L1CAM,LAMA2,LIMS1,LMO1,SMAD1,SMAD9,MAN2A2,MAPT,MARK3,AQP11,MDFI,MDM4,MEF2C,MEST,KITLG,PPM1L,MITF,AFF1,MMP16,GIT1,ADAM22,MYCN,MYH6,MYO5A,MYT1,NEK1,NEUROD1,NF1,NFIA,NFE2L2,NKX2-2,NOVA1,NOVA2,NPR2,SLC11A2,NRCAM,NRDC,NTRK2,NTRK3,ODF2,PAX6,PBX1,PCSK1,PDGFRA,PIK3R1,PKD1,PLEC,FTO,PLP1,PMP22,RC3H2,SCHIP1,MAGEL2,MBOAT7,POU3F2,PRKACB,MAPK8,MAPK9,HYDIN,PROX1,RELN,PTCH1,PTHLH,PEX2,PEX5,CCDC40,ARID4A,RET,FIGN,RGS4,RGS10,RIC8B,KIRREL1,ROBO2,GLDN,RPL38,LGR4,RXRA,STX1B,SATB1,SBF1,CSRNP3,ATXN1,SCN2A,SCN8A,FNIP1,SMPD3,SOX6,CASC3,SCG5,ARX,FERMT1,FHOD3,SLC1A2,SMTN,LIMS2,SLC6A9,CCDC88A,SHANK2,SLC12A2,SLC14A1,CPEB4,EPC1,SMARCA4,SMARCC2,CDK5RAP2,SNAP25,MBD5,SNRPN,SOX1,SOX2,SOX3,SOX10,SOX11,SP2,SP4,SPP1,ZNF423,NPAS3,NFASC,TAB2,MESP1,SMOC1,MAPK8IP3,SULF2,VAMP1,PLCB1,SYT1,CAMTA1,MGRN1,TCF4,ZEB1,TCF12,SYNE1,AKNA,FRYL,TF,DICER1,SIRT1,ZFPM2,LEFTY2,THRA,TIE1,HEY1,TK2,HEY2,RBFOX2,RGMB,TRIO,CA14,TSC1,TSC2,UBE3A,FLRT2,USP1,VGF,VLDLR,LMF1,NSD2,LGI4,ZIC1,ZIC2,ZIC3,CELF4,ANKS1B,SMARCAD1,MAP3K12,LRP8,SNX27,TMEM163,SLC17A6,PDSS2,NLRP3,VANGL2,TTC7A,ST8SIA2" Mouse Phenotype MP:0009454 impaired contextual conditioning behavior 2.10E-05 1.68E-01 1.03E-03 9.84E-03 34 79 "PTCHD1,KCNAB2,CDC14B,TMEM108,ATP1A3,KSR1,CAMK2A,CAMK2B,SHISA7,DRD1,DYRK1A,EFNA3,TMEM35A,ERBB4,NRN1,FGF14,GAD2,GRIA2,GRIN2C,MAPT,GIT1,NLGN3,RASGRF1,CARF,ITSN1,ARX,SLC6A8,CCDC88A,SP4,STX1A,WWC1,UBE3A,ZIC2,SLC17A6" Mouse Phenotype MP:0005267 abnormal olfactory cortex morphology 2.14E-05 1.71E-01 1.03E-03 9.84E-03 15 24 "SEMA7A,ATP1A2,PTBP2,SLIT2,LHX2,TBR1,RELN,CRTAC1,ROBO1,ROBO2,SLIT1,SOX1,SOX2,NR2E1,MAP3K12" Mouse Phenotype MP:0002578 impaired ability to fire action potentials 2.14E-05 1.71E-01 1.03E-03 9.84E-03 15 24 "SLC12A5,KCNT1,ANK3,MADD,CACNA1G,KCNMB2,ETV1,GAD2,GRIA1,GRIA4,KCNA2,KCNMA1,NEUROD1,NALCN,NFASC" Mouse Phenotype MP:0004008 abnormal GABA-mediated receptor currents 2.14E-05 1.71E-01 1.03E-03 9.84E-03 15 24 "SLC12A5,NRXN1,NRXN2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG2,KIF5A,SLC26A11,STX1B,SLC6A1,UBE3A" Mouse Phenotype MP:0008840 abnormal spike wave discharge 2.14E-05 1.71E-01 1.03E-03 9.84E-03 15 24 "ATP1A3,HCN2,CACNA1G,CACNA1A,LGI1,CACNA2D2,HDAC4,ELAVL3,GABRA1,GNAO1,GRIA4,SLC10A4,SCN8A,ARX,CELF4" Mouse Phenotype MP:0001475 reduced long term depression 2.39E-05 1.91E-01 1.14E-03 1.09E-02 22 43 "LRRC7,CDK5R1,WASF1,CAMK2A,CHRM1,CNR1,AKAP5,CSPG5,GFAP,GRM1,GRM2,LAMA2,MYO5A,PRKAR1B,SCN4B,SHANK2,NCDN,ARHGEF9,WWC1,VGF,ANKS1B,SLC17A6" Mouse Phenotype MP:0011380 enlarged brain ventricles 2.47E-05 1.97E-01 1.17E-03 1.12E-02 61 171 "KIDINS220,ASPA,NUMB,BBS2,WASF1,PTBP2,BRSK2,DCLK1,NUMBL,CHN1,CLCN3,CSF1R,SRGAP3,ARNT2,CDON,DRD1,PDCD6IP,DSCAM,DNM1L,EDIL3,EML1,PRMT5,VTI1B,EVL,BRSK1,CHL1,GLDC,GPM6B,HSF2,TUBB2B,KIF2A,L1CAM,PPM1L,BLOC1S2,MYO9A,NFIX,NRDC,PLP1,PLXNB1,POU3F2,HYDIN,RGS4,ZC3H14,ATXN1,SCN8A,ARX,CDK5RAP2,SOX2,MYCBP2,ZNF423,NPAS3,MAPK8IP3,CNTN2,AP4E1,NR2E1,TP53BP2,TSC1,ZIC2,SLC17A6,FZD3,VANGL2" Mouse Phenotype MP:0009456 impaired cued conditioning behavior 2.67E-05 2.13E-01 1.25E-03 1.20E-02 28 61 "PTCHD1,KSR1,CNR1,DBN1,DRD1,TMEM35A,ENO2,ERBB4,NRN1,FGF13,FGF14,GAD2,MAPT,GIT1,FXYD6,IDNK,PDE4B,NLGN3,ARX,SLC6A1,ANKFN1,KIF21B,SP4,WWC1,CRTC1,ZIC2,SLC17A6,FZD3" Mouse Phenotype MP:0002804 abnormal motor learning 2.67E-05 2.13E-01 1.25E-03 1.20E-02 28 61 "SLC12A5,ALS2,ATM,ADGRB3,RGS9,BCL2L2,SGCE,CACNA1G,CA8,GPR37L1,CHRNA4,NRXN1,SLC24A2,DSCAM,ENO2,GABRA1,IP6K3,C1QL1,GRIN1,MAPT,NRCAM,HCN1,FA2H,CNTNAP3,SLC6A8,SST,UBE3A,GJC2" Mouse Phenotype MP:0008414 abnormal spatial reference memory 3.07E-05 2.45E-01 1.43E-03 1.37E-02 33 77 "ASIC1,LRRC7,APP,KSR1,CACNA1B,CAMK2A,DGKB,BRINP1,SRGAP3,SHANK1,MBNL2,TMEM35A,ENO2,FGF14,GABRA1,GABRG2,CPLX2,GRIA1,GRIA2,GRIA4,KCNJ11,RELN,RASGRF1,CARF,CPEB3,SLC6A8,MTERF2,SP4,CLSTN2,DDHD2,NR2E1,LRP8,SLC17A6" Mouse Phenotype MP:0002961 abnormal axon guidance 3.42E-05 2.73E-01 1.59E-03 1.52E-02 31 71 "NRP2,BMPR1B,ISPD,DCLK1,SLIT2,VAX2,CNTN1,PLXNA4,DCC,EDIL3,CELSR3,EPHB1,ETV1,TUBB3,FGFR1,VTI1B,GAP43,SRRM4,L1CAM,FEZF2,RET,ROBO1,ROBO2,SLIT1,SOX1,SOX10,MYCBP2,MAPK8IP3,ROBO3,VAV2,PRDM8" Mouse Phenotype MP:0001899 absent long term depression 3.58E-05 2.86E-01 1.65E-03 1.58E-02 21 41 "ADCY8,ADGRB3,RGS9,CDK5R1,CAMK2A,CNR1,PICK1,AKAP5,CALY,C1QL1,GRIA1,GRIA2,GRIN1,NR3C1,NCAM1,NOS1,NLGN3,PRKACB,RYR3,SORCS3,DPYSL5" Mouse Phenotype MP:0002068 abnormal parental behavior 3.68E-05 2.94E-01 1.69E-03 1.62E-02 61 173 "LRRC7,APC,CACNA1A,KALRN,CAMK2B,NEURL1,RAB3C,NRXN1,WHRN,CNTNAP2,RIMS2,SNAP91,DLG4,SHANK1,DSCAM,EFNA3,CSPG5,FYN,GABRA1,GABRB3,GLRB,GNAL,GRIA2,GRIN1,GRM1,HNF4G,NKD1,DOCK7,MAP6,MBP,MEST,MITF,MYO7A,NOS1,NRCAM,OXTR,ABCB1,NLGN3,TMIE,MAGEL2,RAB3A,FIGN,NLGN1,SHANK2,SLC12A2,SOX1,NPAS3,TBX15,ZEB1,CRTC1,ATP13A2,SIRT1,CHST8,THRA,NR2E1,UBE3A,LGI4,FMN2,TUBA1A,PCDH15,TMEM163" Mouse Phenotype MP:0004274 abnormal embryonic/fetal subventricular zone morphology 3.85E-05 3.08E-01 1.76E-03 1.68E-02 28 62 "APAF1,ASCL1,SLIT2,BOC,CDON,EBF1,EDIL3,CELSR3,EMX2,PRMT5,FOXG1,SRRM4,HES5,ITGAV,PAX6,POU3F2,ROBO1,FBXW7,SLIT1,CDK5RAP2,SOX11,SP2,SPTAN1,CUX2,NR2E1,TP53BP2,PDSS2,IFT88" Mouse Phenotype MP:0002752 abnormal somatic nervous system morphology 4.15E-05 3.31E-01 1.88E-03 1.80E-02 270 1001 "DSCAML1,ADRB2,CC2D2A,SEMA6A,ALCAM,BCAR3,ABCD2,PPFIA2,APAF1,GAS7,ALS2,APP,MADD,SPTBN4,ASCL1,CHRD,NUMB,ATP2B2,BBS2,NRP2,PROM1,BMPR1B,SYNJ2,MTMR2,BSN,MYRF,CACNA1D,CACNB2,CACNB4,KALRN,CAMK2A,BRSK2,RGN,AIFM1,CD86,CDH8,NOG,CACNA2D2,ASIC3,CHM,CHN1,LHX2,PLAA,CLCN3,VAX2,TMEM184B,CNGA3,WHRN,SLC4A7,CP,CRY2,CLIP3,CSF3R,LRIG1,PLXNA4,ERC2,CX3CR1,RIPOR2,DBN1,DCC,DCTN1,HEPH,GSDME,DLX1,DMD,OLIG1,TRAPPC9,CPEB2,SLC12A6,DSCAM,DTNA,USH1C,WDPCP,EDNRA,EDNRB,EEF1A2,HEYL,EFNA2,EGFR,MBNL2,EGR3,C8orf37,EMX2,OLIG2,ENO2,EPHA5,EPHB1,GPHN,EPS8,ERBB2,ERBB4,ETV1,ADGRV1,EYA1,CACNG2,TUBB3,SEC24B,FGFR1,FGFR3,FOXG1,FOXF2,VTI1B,POMT1,DLL3,TBR1,FYN,MEGF11,MEGF10,GABBR1,GABRA5,CHL1,GABRB3,ZMYND11,GALC,NKX6-2,SALL3,GAP43,ATP8A2,SRRM4,GBX2,GFRA1,GFRA2,KIRREL3,GJB1,GLRB,PRRC2B,GRID1,GRIN1,GRM7,RNF165,MFSD2A,GUCY1A1,TLX1,DHX35,IGF1,ZIC5,HES5,ITGA7,KCNJ10,KCNMA1,KIF5C,KIT,L1CAM,LAMA2,LIFR,SMAD1,MAPT,MBNL1,SHC3,MEIS2,MITF,MOG,MYCN,MYO6,MYO7A,NDP,NEFH,NEUROD1,NF1,NOS1,NPR2,NRCAM,NRDC,HCN1,NTRK2,NTRK3,OPA1,CLDN11,PAX6,PDPK1,SERPINE2,SEMA5B,TMIE,RETREG1,GPSM2,PLP1,PMP22,FA2H,FAT3,POLG,POU3F4,PRKACB,MAPK9,MAPK10,PROX1,PRPH,RELN,PTCH1,PTPN13,STRC,SH3TC2,ATG16L1,FAT4,FEZF2,RDX,RET,RFX3,RLBP1,RIC8B,SETD5,ROM1,RORB,RPE65,LGR4,WLS,RXRA,ATXN7,SCN8A,ASIC4,ELMOD1,ANKRD6,SLC1A3,SLC4A3,SLC12A2,SLC20A2,CPEB4,SNCA,SOX2,SPATA7,SOX10,SOX11,NMNAT2,MYCBP2,ZNF423,NFASC,MESP1,SMOC1,SSTR1,SSTR2,MAPK8IP3,ELOVL4,SYNE2,ATP11A,SEMA4A,CNTN2,AGTPBP1,SATB2,CUX2,ZEB1,TRIM2,RPGRIP1L,SYNE1,DICER1,SIRT1,CRB1,ZNF106,THRA,HEY1,TLR4,NR2E1,PARD3,TP53BP2,WBP2,TUB,UCHL1,VAV2,VLDLR,LGI4,ZIC2,ZIC3,CRB2,MAP3K12,PCDH15,NAV2,FZD3,GJC2,VANGL2,MSRB3,NETO1,GAN" Mouse Phenotype MP:0011003 reduced AMPA-mediated synaptic currents 4.26E-05 3.40E-01 1.92E-03 1.84E-02 13 20 "CNIH2,KALRN,SHISA7,NRXN1,NRXN2,CNIH3,DLG4,CACNG7,CACNG2,GRIA1,GRIN1,LRRTM1,NLGN3" Mouse Phenotype MP:0001488 increased startle reflex 4.32E-05 3.44E-01 1.94E-03 1.85E-02 40 101 "LRFN2,KIAA1324,B3GALT2,CCK,ZBTB24,DRD1,KIAA1109,SGIP1,GABRA1,GABRA3,DISC1,CPLX2,PPARGC1A,GLRB,ATF7,GRIK5,GRIN1,GRIN2D,ATE1,NXPH3,KCNA1,NF1,PRODH,LAMA1,FIGN,SH3BP2,PREX2,SLC6A1,SLC8A3,BEX1,STX1A,AJAP1,JMJD6,AP4E1,TSC1,SSBP2,ZIC2,SLC17A7,PDSS2,EPM2A" Mouse Phenotype MP:0012348 decreased susceptibility to induction of seizure by inducing agent 4.35E-05 3.47E-01 1.94E-03 1.85E-02 18 33 "ADORA2A,CACNA1G,P2RX6,CLCN3,AKAP5,SEZ6,GABRG2,GAD2,GRIK2,GRIN1,GRM5,MAPT,NPY,MAPK10,SCN8A,SLC6A11,CELF4,SLC4A10" Mouse Phenotype MP:0003463 abnormal single cell response 5.68E-05 4.54E-01 2.52E-03 2.41E-02 21 42 "ADCY8,PTCHD1,SEMA6A,ADGRB3,RGS11,CACNA1G,CACNA1B,CHRNB2,CLOCK,GRIN3A,GABRB1,C1QL1,GRIK2,GRIN1,GRM7,KCNA2,RGS7,SCN4B,TRPC1,TSC1,SLC17A7" Mouse Phenotype MP:0003412 abnormal afterhyperpolarization 5.90E-05 4.71E-01 2.60E-03 2.49E-02 12 18 "KCNAB2,ADGRB3,HCN2,DPP6,JPH4,C1QL1,KCNC2,KCNQ2,KCNQ3,SLC26A11,KCNAB1,JPH3" Mouse Phenotype MP:0005656 decreased aggression 6.01E-05 4.80E-01 2.64E-03 2.52E-02 23 48 "SYN3,APBA2,BBS2,ARHGAP32,EN2,GAD2,KIRREL3,GRIA1,GRIA2,GRIN1,LAMA2,LSAMP,MAG,MAP6,NOS1,OPHN1,RGS4,RORB,ARX,TACR1,TSN,ZIC2,PAK5" Mouse Phenotype MP:0001496 audiogenic seizures 6.19E-05 4.94E-01 2.70E-03 2.58E-02 14 23 "LGI1,TPP1,ADGRV1,FYN,GABBR1,B4GALNT1,GNG3,GRM5,HLF,MBP,PAH,PRRT2,ST8SIA1,UBE3A" Mouse Phenotype MP:0001524 impaired limb coordination 6.54E-05 5.22E-01 2.84E-03 2.71E-02 31 73 "PLA2G6,CNTNAP1,ATP2B2,CACNA1A,CACNB4,CALB1,CNTN1,GAL3ST1,DNM1,SLC12A6,EFNB3,ERBB2,ETV1,FDFT1,GALC,ATP8A2,GLI2,GRM1,GRM7,ITGAV,L1CAM,PPM1L,MYO5A,NTRK3,RORB,SCN8A,VAMP1,ZNF106,TRPC3,ZIC1,RNF170" Mouse Phenotype MP:0003651 abnormal axon extension 6.60E-05 5.27E-01 2.85E-03 2.72E-02 35 86 "SYN3,SEMA7A,APBB1,APBB2,CDK5R1,BRSK2,CHN1,NGEF,KIF26A,EMX2,EPHB1,GPHN,NRN1,VTI1B,BRSK1,NKX6-2,GAP43,SRRM4,GPM6A,RNF165,KIF2A,L1CAM,MAPT,NEFH,NFIA,NTRK2,ENPP2,RELN,ROBO1,LRRK2,CPEB4,NMNAT2,MYCBP2,UNC5D,RTN4" Mouse Phenotype MP:0012079 abnormal spinal reflex 7.26E-05 5.80E-01 3.10E-03 2.96E-02 40 103 "ADCY8,SLC12A5,PRX,MADD,ATP1A2,KIF1A,BBS2,CDK5R1,CDK5R2,CACNA1A,CACNA1B,BRSK2,CCKBR,ASIC3,ARHGEF4,DLG2,FGF11,FLNC,NBEA,BRSK1,GABBR1,GRM7,KCND2,L1CAM,PCSK2,PDYN,PTPRG,KCNIP3,RYR1,ELMOD1,SLC6A9,SNAP25,SOX10,SPP1,KIF1B,ERBIN,TACR1,TLR4,TSC1,SLC17A7" Mouse Phenotype MP:0005316 abnormal response to tactile stimuli 7.26E-05 5.80E-01 3.10E-03 2.96E-02 40 103 "ADCY8,SLC12A5,PRX,MADD,ATP1A2,KIF1A,BBS2,CDK5R1,CDK5R2,CACNA1A,CACNA1B,BRSK2,CCKBR,ASIC3,ARHGEF4,DLG2,FGF11,FLNC,NBEA,BRSK1,GABBR1,GRM7,KCND2,L1CAM,PCSK2,PDYN,PTPRG,KCNIP3,RYR1,ELMOD1,SLC6A9,SNAP25,SOX10,SPP1,KIF1B,ERBIN,TACR1,TLR4,TSC1,SLC17A7" Mouse Phenotype MP:0009453 enhanced contextual conditioning behavior 8.04E-05 6.42E-01 3.41E-03 3.26E-02 15 26 "LRFN2,APP,FABP7,NBEA,GABRA2,GABRB3,DISC1,LRRTM1,GPR85,KCNIP3,CPEB3,SLC8A2,SPIRE1,RNF103,TMEM163" Mouse Phenotype MP:0000830 abnormal diencephalon morphology 1.02E-04 8.15E-01 4.31E-03 4.12E-02 98 317 "ALK,APAF1,ASPA,CHRD,NUMB,BBS2,NRP2,CACNB4,HAP1,DCLK1,NOG,NUMBL,CACNA2D2,CHRNB2,ZNF521,NCOR1,ARNT2,DMD,TRAPPC9,DSCAM,DYRK1A,E2F5,EDIL3,EFNA2,EFNA3,CELSR3,EMX2,ENO2,EYA1,CACNG2,FOXG1,NBEA,FYN,DISC1,GBX2,GDF1,GHR,GLI2,CIT,DHX35,HSF2,ATCAY,ZIC5,IGSF1,HES5,INSM1,LIG4,SYTL4,MYO9A,NEK1,NF1,NFIA,NFIX,NODAL,DDR2,OPHN1,PAX6,PDPK1,PKD1,MBOAT7,POU3F2,MAPK8,MAPK9,PTCH1,FEZF2,SETD5,FBXW7,ATXN1,SMPD3,SCG5,ARX,FUZ,SLC20A2,TET1,MBD5,SOX2,SOX3,MYCBP2,ZNF423,NPAS3,MAPK8IP3,ATP11A,AGTPBP1,DMXL2,TCF7L2,RPGRIP1L,SIRT1,THRA,TIAM1,TP53BP2,TRH,TUB,ZIC3,SLC17A6,FZD3,VANGL2,IFT88,ST8SIA2" Mouse Phenotype MP:0013229 abnormal brain ventricle size 1.14E-04 9.08E-01 4.78E-03 4.57E-02 61 179 "KIDINS220,ASPA,NUMB,BBS2,WASF1,PTBP2,BRSK2,DCLK1,NUMBL,CHN1,CLCN3,CSF1R,SRGAP3,ARNT2,CDON,DRD1,PDCD6IP,DSCAM,DNM1L,EDIL3,EML1,PRMT5,VTI1B,EVL,BRSK1,CHL1,GLDC,GPM6B,HSF2,TUBB2B,KIF2A,L1CAM,PPM1L,BLOC1S2,MYO9A,NFIX,NRDC,PLP1,PLXNB1,POU3F2,HYDIN,RGS4,ZC3H14,ATXN1,SCN8A,ARX,CDK5RAP2,SOX2,MYCBP2,ZNF423,NPAS3,MAPK8IP3,CNTN2,AP4E1,NR2E1,TP53BP2,TSC1,ZIC2,SLC17A6,FZD3,VANGL2" Mouse Phenotype MP:0003990 decreased neurotransmitter release 1.21E-04 9.62E-01 5.04E-03 4.82E-02 18 35 "DOC2A,CACNA1A,CACNA2D2,CHRNA4,RAB3C,NRXN1,NRXN2,SLC32A1,DLG4,EEF1A2,EN2,NOS1,RAB3A,SNAP25,SSTR1,PRMT8,UCHL1,SLC17A6" Mouse Phenotype MP:0000771 abnormal brain size 1.28E-04 1.00E+00 5.25E-03 5.02E-02 112 373 "ARID1A,KIDINS220,APAF1,APP,CHRD,WASF1,HAP1,BRSK2,AIFM1,CD81,ARHGEF2,ARHGAP33,NOG,CACNA2D2,COPB2,LHX2,PLAA,PPT2,CLCN3,NIPBL,ZNF521,AATK,CYBB,PLPPR4,NYAP1,SLC12A6,DRD1,PDCD6IP,DYRK1A,DNM1L,EDIL3,EGFR,EN2,EPB41L1,EPB41L2,PRMT5,FGF14,FOXG1,VTI1B,NBEA,TBR1,BRSK1,GAD1,DISC1,GFAP,GHR,KDM2B,GPT2,ATE1,CIT,TUBB2B,KCNA1,KCNJ10,KIF5C,LAMA2,LAMP2,LIG4,MAPT,MBD1,MEF2C,AFDN,BLOC1S2,MYCN,NCAM1,RCOR2,NEUROD1,NF1,NFIX,NODAL,NRDC,OPHN1,PDPK1,GPR85,NLGN3,MBOAT7,PTHLH,PEX2,KHDRBS2,WLS,ATXN1,ATXN7,ITSN1,ARX,SIRT2,CCDC88A,CDK5RAP2,MBD5,MYO16,SOX1,SOX11,ZNF423,SPTB,KIF1B,MAPK8IP3,MLC1,PLCB1,SYN2,TCF4,CUX2,SIRT1,NR2E1,TRIO,TSC1,TSC2,UBE3A,VLDLR,ZIC2,ZNF24,LRP8,PDSS2,UBE3B,IFT88" Mouse Phenotype MP:0004996 abnormal CNS synapse formation 1.28E-04 1.00E+00 5.25E-03 5.02E-02 19 38 "BCL2L2,KALRN,CHRM1,NRXN1,NRXN2,SHANK1,DTNA,DTNB,DNM1L,NRN1,CACNG2,ACTL6B,FOXG1,IP6K3,NLGN3,LRRTM4,STAU1,SYN1,SYN2" Mouse Phenotype MP:0004770 abnormal synaptic vesicle recycling 1.28E-04 1.00E+00 5.25E-03 5.02E-02 12 19 "AMPH,DNAJC6,SNAP91,DNM1,DBNL,PACSIN1,STX1B,ITSN1,SH3GL2,SH3GL3,STX1A,SYN1" Mouse Phenotype MP:0002916 increased synaptic depression 1.28E-04 1.00E+00 5.25E-03 5.02E-02 12 19 "SYN3,SYNJ1,PCLO,KCNMA1,RAB3A,SH3GL2,SH3GL3,SYN1,SYN2,SYT1,UCHL1,ELFN1" Mouse Phenotype MP:0005237 abnormal olfactory tract morphology 1.33E-04 1.00E+00 5.41E-03 5.17E-02 9 12 "SEMA7A,PTBP2,SLIT2,TBR1,CRTAC1,ROBO1,ROBO2,SLIT1,MAP3K12" Mouse Phenotype MP:0008439 abnormal cortical plate morphology 1.34E-04 1.00E+00 5.41E-03 5.17E-02 22 47 "CDK5R1,CDK5R2,BRSK2,LHX2,NCOR2,EMX2,PRMT5,FOXG1,EVL,BRSK1,IL6ST,TUBB2B,AFDN,BLOC1S2,NTRK2,PAX6,FBXW7,ARX,SP2,MAPK8IP3,USP22,TP53BP2" Mouse Phenotype MP:0004101 abnormal brain interneuron morphology 1.34E-04 1.00E+00 5.41E-03 5.17E-02 21 44 "SLC12A5,ASCL1,ATM,CACNA1A,CNTNAP2,BRINP1,OLIG1,CHL1,GAD1,NKX6-2,DCLK2,GRIA2,TUBB2B,PDYN,ROBO2,SATB1,ARX,ZNF365,MYCBP2,TMEM163,ST8SIA2" Mouse Phenotype MP:0000886 abnormal cerebellar granule layer morphology 1.41E-04 1.00E+00 5.66E-03 5.41E-02 47 130 "ABR,SLC12A5,SORCS2,SEMA6A,SEMA4G,NUMB,ASTN1,ATM,ATP2B2,BID,CDK5R1,CACNA1A,CBLN1,AIFM1,LGI1,PPT2,CNTN1,CP,EDIL3,EN2,ENO2,ERBB4,APC2,FGF13,GLI2,GRIN2C,CIT,L1CAM,MDM4,MYCN,NEUROD1,NFIA,NRCAM,PAX6,PDYN,SERPINE2,PLP1,PLXNB1,RELN,LAMA1,PEX2,SCN8A,TNIK,CAMTA1,AGTPBP1,TRIO,XRCC4" Mouse Phenotype MP:0005076 abnormal cell differentiation 1.48E-04 1.00E+00 5.89E-03 5.63E-02 202 736 "ABR,SYN3,AXIN2,FZD9,ADRB2,KIDINS220,MRTFA,SEMA7A,APAF1,APBB1,APBB2,APC,APP,ASCL1,NUMB,ATM,ATP2A2,ATP2B2,NRP2,KSR1,BMPR1B,CDK5R1,CDK5R2,CACNA1D,HAP1,PTBP2,BRSK2,ISPD,CBS,CDC25B,CDH2,DCLK1,NUMBL,GPR37L1,ADGRG1,CHN1,CHN2,SLIT2,NGEF,VAX2,NIPBL,CNR1,CNTN1,ZNF521,CREB5,NCOR1,NCOR2,ABCG1,CSF1,CSF1R,CSF3R,LRIG1,PLXNA4,ARHGAP32,KIF26A,RASSF2,BRINP1,GIT2,DCC,DSCAM,EDIL3,EFNA2,EFNB3,CELSR3,EGFR,EIF4G2,ELAVL4,BSCL2,EML1,EMX2,OLIG2,EPHB1,GPHN,ETV1,EYA1,NRN1,CACNG2,TUBB3,FCGR1A,FGFR1,FGFR3,SUCO,FOXG1,VTI1B,FOXO3,EVL,FLT1,ZCCHC17,ATP6V1H,BRSK1,ILDR2,NKX6-2,GAP43,SIGLEC8,SRRM4,GBX2,GFAP,GLI2,GPM6A,GRIA2,DIDO1,NR3C1,GSN,RNF165,HMX1,RBPJ,SCIN,HES5,IL6ST,INSM1,ITGAV,JAK2,KIF2A,L1CAM,SMAD1,MAPT,MBD1,MEF2C,AFDN,BLOC1S2,MYCN,NCAM1,NEFH,NEUROD1,NF1,NFIA,NKX2-2,NOS1,NTRK2,PAX6,PCSK2,PDE4B,ENPP2,PDPK1,PKD1,GPSM2,PLCD1,PLXNB1,MBOAT7,PPARA,MAPK8,MAPK9,RELN,LAMA1,PTCH1,PTHLH,PTPRE,PTX3,ARID4A,FEZF2,CRTAC1,RET,RGS10,KIF7,ROBO1,ROBO2,FBXW7,LRRK2,IL17RB,RASA3,SH3BP2,SLA,SLC1A3,CCDC88A,TET1,SLIT1,CPEB4,SMARCC2,SOX1,SOX2,TNIK,SOX10,SOX11,SP2,NMNAT2,MYCBP2,MAPK8IP3,ATP11A,ROBO3,UNC5D,SIN3B,SATB2,USP22,SIK3,DICER1,TLR4,NR2E1,TP53BP2,TRIO,TSC1,VAV2,TRIM9,REEP1,MAP3K12,GDPD5,PRDM8,TMEM178A,PDSS2,RTN4,NLRP3,RNF146,ST8SIA2" Mouse Phenotype MP:0009746 enhanced behavioral response to xenobiotic 1.49E-04 1.00E+00 5.90E-03 5.64E-02 32 79 "UNC79,ALK,ATP1A1,ATP1A3,CACNA1A,CACNA1B,CCKBR,CHRM4,CHRNA4,TAOK2,DLGAP3,CLCN3,CLOCK,SLITRK5,DLG4,PPP1R1B,FYN,GABRA2,GABRB1,GABRG2,KCNC1,LAMP2,NOS1,NTRK2,PRKCG,RYR1,SCN8A,PPP1R9A,SLC6A1,NCDN,ADGRL3,ANKS1B" Mouse Phenotype MP:0002204 abnormal neurotransmitter level 1.52E-04 1.00E+00 6.00E-03 5.74E-02 73 225 "SLITRK1,SORCS2,APBA2,DDO,AQP4,ARNTL,ASPA,ATP1A2,ATP2A2,CDK5R1,CACNA1A,CD81,CHGA,CHGB,CHRM1,CHRM4,MAGED1,PNKD,FEZ1,ERC2,RIMS2,DBT,BLOC1S6,CPEB2,ELAVL3,ELAVL4,EN2,FYN,GAD1,GAD2,DISC1,PPARGC1A,GLUL,GNAS,GPD2,MCHR1,GPR37,GRIA1,NR3C1,GRM2,GSTM5,HLF,HNMT,KIT,MAOB,MITF,NOS1,NPPA,OPRL1,PAH,FTO,SH3KBP1,MAPK9,MAPK10,PRODH,KHDRBS2,MRAP2,LRRK2,DGLUCY,SLC6A8,SNAP25,SNCB,SNCA,SSTR2,STX1A,TACR1,ADGRL3,CRTC1,UBE3A,VAV2,VGF,REEP1,SLC17A6" Mouse Phenotype MP:0000813 abnormal hippocampus layer morphology 1.55E-04 1.00E+00 6.11E-03 5.84E-02 42 113 "AGT,MRTFA,CADPS,TMEM108,ATP1A3,CDK5R1,CDK5R2,KALRN,CAMK2A,CD81,DCLK1,CLCN3,ZNF521,CRMP1,CSF1,CTNND1,DLG4,SHANK1,EFNA3,ABI2,APC2,FGF14,FOXG1,DPYSL4,FYN,DCLK2,KIF2A,MAP2,MAPT,AFDN,NCAM1,NEUROD1,PROX1,RELN,CPEB3,SLC1A2,SYN1,TNR,TSC1,TSC2,LRP8,TUBA1A" Mouse Phenotype MP:0010053 decreased grip strength 1.63E-04 1.00E+00 6.37E-03 6.09E-02 89 286 "ACHE,SLITRK1,PLA2G6,LTBP4,GAS7,APP,ASPA,ATP2B2,RGS9,CACNA1A,CACNA1B,CAMK2B,CD86,PLAA,NRXN1,TMEM184B,CRYM,CX3CR1,DLG4,DMD,DRD1,DTNA,DTNB,USH1C,MBNL2,EIF4G2,EN2,OLIG2,EFEMP1,FKTN,FGF12,FGF14,FHL1,CAP2,FLNC,FYB1,GAA,GAD1,GATM,PPARGC1A,GRIA2,GRIA4,GRM7,RNF165,PSIP1,FRMD5,VSIG4,NEGR1,KCNA2,L1CAM,SMAD9,MBNL1,NRCAM,NRDC,PMP22,MAGEL2,PYGM,SH3TC2,SETD5,RYR1,SCN8A,ELMOD1,SH3GL2,CCDC92,WDR37,SLC2A5,WDR47,SLC6A8,SIRT2,MBD5,SOX1,ZHX3,MLC1,FGD4,AP4E1,ZNF106,GALNT17,THRA,NACC2,TNFRSF1B,SSBP2,UCHL1,FRRS1L,ELFN1,EPM2A,UBE3B,PAK5,RNF170,FXR1" Mouse Phenotype MP:0008948 decreased neuron number 1.65E-04 1.00E+00 6.37E-03 6.09E-02 134 462 "ADRB2,KIDINS220,SEMA6A,BCAR3,ANK3,GAS7,ALS2,PRX,ASCL1,NUMB,ATP2B2,CACNA1G,CACNA1A,CACNA1D,CACNB2,CRLF1,CACNA2D2,CHM,CHRNA4,CLCN3,CNGA3,CNTFR,WHRN,SLC4A7,CP,CRY2,CSF1,PLXNA4,CX3CR1,DCTN1,GSDME,OLIG1,DNM1L,EDIL3,HEYL,EGFR,EGR3,C8orf37,EMX2,EN2,OLIG2,ENO2,GPHN,ERBB2,ETV1,EYA1,FGF13,FGF14,FGFR1,FOXG1,SMC2,GABRA1,ATP8A2,SRRM4,GFRA1,PPARGC1A,GLI2,GRIA2,GRM7,GUCY1A1,ACOT7,IGF1,INSM1,KIF5C,KIT,LAMA2,LIFR,MDM4,MITF,GIT1,MYCN,MYO6,MYO7A,NDP,RCOR2,NEFH,NEUROD1,NHLH1,NTRK2,NTRK3,OPA1,PAX6,PCDH9,ANKRD16,RELN,KLK6,RET,RFX3,RLBP1,RIC8B,RORB,RPE65,FBXW7,RXRA,ATXN1,ATXN7,SCN8A,ARX,SLC1A2,SLC1A3,SIRT2,CCDC88A,SLC12A2,SNCA,SOX2,TNIK,SOX10,SOX11,NMNAT2,ZNF423,KIF1B,SMOC1,STXBP1,SYNE2,SEMA4A,AGTPBP1,ATMIN,TRIM2,SLC19A3,CRB1,ZNF106,NR2C2,TRPC3,TSC1,TUB,ZIC2,CRB2,MAP3K12,LRP8,GDPD5,TUBA1A,PDSS2,VANGL2,ST8SIA2" Mouse Phenotype MP:0002887 decreased susceptibility to pharmacologically induced seizures 1.65E-04 1.00E+00 6.37E-03 6.09E-02 16 30 "CACNA1G,P2RX6,CLCN3,AKAP5,SEZ6,GABRG2,GAD2,GRIK2,GRIN1,GRM5,MAPT,NPY,MAPK10,SCN8A,SLC6A11,SLC4A10" Mouse Phenotype MP:0002826 tonic seizures 1.65E-04 1.00E+00 6.37E-03 6.09E-02 16 30 "AMPH,CACNB4,LGI1,CACNA2D2,CHN1,QKI,HDAC4,BLOC1S6,DNM1,FYN,GJB1,KCNA2,MBP,ARX,ZNF24,GJC2" Mouse Phenotype MP:0003863 decreased aggression towards mice 1.81E-04 1.00E+00 6.91E-03 6.61E-02 17 33 "SYN3,APBA2,ARHGAP32,EN2,GAD2,KIRREL3,GRIA1,GRIA2,GRIN1,LSAMP,MAG,NOS1,OPHN1,RGS4,ARX,ZIC2,PAK5" Mouse Phenotype MP:0000792 abnormal cortical marginal zone morphology 1.81E-04 1.00E+00 6.91E-03 6.61E-02 17 33 "APAF1,APBB1,APBB2,PRX,NUMB,CDK5R1,CDK5R2,NUMBL,ADGRG1,CELSR3,HES5,KIT,RELN,ARX,MAPK8IP3,VLDLR,LRP8" Mouse Phenotype MP:0020527 small thalamus 1.82E-04 1.00E+00 6.91E-03 6.61E-02 11 17 "NUMB,NUMBL,NCOR1,EMX2,FOXG1,DISC1,ZIC5,PAX6,FEZF2,FBXW7,ZNF423" Mouse Phenotype MP:0000965 abnormal sensory neuron morphology 1.84E-04 1.00E+00 6.96E-03 6.65E-02 144 503 "DSCAML1,ADRB2,CC2D2A,SEMA6A,ALCAM,BCAR3,APAF1,ASCL1,ATP2B2,BBS2,NRP2,PROM1,BMPR1B,BSN,CACNB2,BRSK2,AIFM1,CDH8,NOG,ASIC3,CHM,LHX2,CLCN3,VAX2,CNGA3,WHRN,SLC4A7,CP,CRY2,LRIG1,PLXNA4,ERC2,CX3CR1,DCC,HEPH,GSDME,OLIG1,CPEB2,DSCAM,HEYL,EFNA2,EGFR,EGR3,C8orf37,EMX2,OLIG2,ENO2,EPHA5,EPHB1,ERBB2,ERBB4,ETV1,EYA1,FGFR1,FGFR3,FOXG1,POMT1,TBR1,MEGF11,MEGF10,GABRA5,CHL1,GABRB3,ATP8A2,SRRM4,GFRA2,KIRREL3,GRM7,MFSD2A,GUCY1A1,TLX1,IGF1,HES5,KCNMA1,KIF5C,L1CAM,LAMA2,MAPT,SHC3,MITF,MYO6,MYO7A,NDP,NEFH,NEUROD1,NF1,NOS1,NPR2,HCN1,NTRK2,NTRK3,OPA1,PAX6,SEMA5B,RETREG1,FAT3,PROX1,PRPH,RELN,PTPN13,FEZF2,RET,RFX3,RLBP1,RIC8B,ROM1,RORB,RPE65,LGR4,RXRA,ATXN7,SLC1A3,SLC4A3,SLC12A2,SOX2,SPATA7,SOX10,SOX11,NMNAT2,MYCBP2,ZNF423,SMOC1,SSTR1,SSTR2,ELOVL4,SYNE2,SEMA4A,CNTN2,AGTPBP1,ZEB1,TRIM2,SIRT1,CRB1,HEY1,TLR4,NR2E1,WBP2,TUB,VAV2,VLDLR,CRB2,MAP3K12,VANGL2,NETO1" Mouse Phenotype MP:0008569 lethality at weaning 1.92E-04 1.00E+00 7.21E-03 6.90E-02 40 107 "CNTNAP1,HCN2,CACNA1A,CLCN3,CNTN1,DBI,SNAP91,DNM2,DPH1,EDIL3,EDNRB,FGFR3,STAMBP,GABRB3,GABRG2,JPH4,ATP8A2,HPSE2,ITGA7,KCNC1,KIF5A,KIT,MYO5A,NFE2L2,NFIX,NALCN,PLP1,PMP22,RELN,WLS,SOX10,ZNF423,STX1A,PLCB1,HEY2,TMEFF2,VLDLR,LRP8,SLC17A7,JPH3" Mouse Phenotype MP:0001415 increased exploration in new environment 1.94E-04 1.00E+00 7.28E-03 6.97E-02 35 90 "ADRA1B,PLA2G6,STX16,BCL7A,CHRNA4,CNR1,CLOCK,ERC2,SIRPA,OLIG1,FGF14,DISC1,GRIA1,GRIA2,GRIN1,HTR5A,KCNC1,L1CAM,LSAMP,OPHN1,PDE4B,PDE1B,SH3KBP1,PKIA,ARX,NPAS3,TAF6,WSCD1,DMXL2,SLC44A1,ZNF142,GDPD5,TMEM163,SLC17A6,ST8SIA2" Mouse Phenotype MP:0012316 enhanced conditioning behavior 2.01E-04 1.00E+00 7.49E-03 7.16E-02 20 42 "LRFN2,APP,ATP1A3,CHRNA4,FABP7,NBEA,GABRA2,GABRA5,GABRB3,DISC1,PRLHR,GRIA1,LRRTM1,GPR85,KCNIP3,CPEB3,SLC8A2,SPIRE1,RNF103,TMEM163" Mouse Phenotype MP:0000774 decreased brain size 2.30E-04 1.00E+00 8.53E-03 8.15E-02 93 304 "ARID1A,KIDINS220,APP,CHRD,WASF1,HAP1,BRSK2,AIFM1,ARHGEF2,ARHGAP33,NOG,CACNA2D2,COPB2,LHX2,PLAA,PPT2,CLCN3,NIPBL,ZNF521,AATK,PLPPR4,NYAP1,DRD1,PDCD6IP,DYRK1A,DNM1L,EDIL3,EGFR,EN2,EPB41L1,EPB41L2,PRMT5,FGF14,FOXG1,VTI1B,TBR1,BRSK1,GAD1,DISC1,GFAP,GHR,GPT2,CIT,TUBB2B,KCNJ10,KIF5C,LAMA2,LAMP2,LIG4,MAPT,MBD1,MEF2C,BLOC1S2,MYCN,NCAM1,RCOR2,NEUROD1,NF1,NODAL,NRDC,PDPK1,NLGN3,MBOAT7,PTHLH,PEX2,KHDRBS2,WLS,ATXN1,ATXN7,ITSN1,ARX,SIRT2,CCDC88A,CDK5RAP2,MYO16,SOX1,SOX11,ZNF423,SPTB,KIF1B,MAPK8IP3,SYN2,TCF4,SIRT1,NR2E1,TRIO,UBE3A,VLDLR,ZIC2,ZNF24,LRP8,PDSS2,UBE3B" Mouse Phenotype MP:0008226 decreased anterior commissure size 2.56E-04 1.00E+00 9.43E-03 9.02E-02 12 20 "APP,ARHGAP5,DCLK1,PLXNA4,EMX2,GPM6B,MAP2,PPM1L,PLP1,DRAXIN,ITSN1,NR2E1" Mouse Phenotype MP:0003477 abnormal nerve fiber response 2.56E-04 1.00E+00 9.43E-03 9.02E-02 12 20 "CACNA1A,ENTPD2,CHN1,SLC32A1,GAD1,GAD2,GRM5,KCNA1,KCNJ11,KCNJ16,KCNMA1,TACR1" Mouse Phenotype MP:0001522 impaired swimming 2.81E-04 1.00E+00 1.03E-02 9.85E-02 31 78 "ABR,CNTNAP1,APP,ATP2B2,HCN2,CACNA1A,WHRN,DRD1,DSCAM,USH1C,SEZ6,CACNG2,FGF14,GABRB3,GLRB,GRM8,KCNA1,KCNMA1,LSAMP,GIT1,DBNL,MYO6,MYO7A,PAH,TMIE,POU3F4,SLC6A8,ANKFN1,SOX2,TSC1,PCDH15" Mouse Phenotype MP:0001417 decreased exploration in new environment 3.01E-04 1.00E+00 1.10E-02 1.05E-01 40 109 "ADORA2A,ADRA1B,ALS2,APP,CHRD,ATP1A1,ATP1A3,CNR1,MAGED1,SLC12A6,DYRK1A,ERCC2,FGF14,JPH4,DISC1,CPLX2,GRIA2,GRIA4,GRM1,GRM8,HSD17B1,LRRTM1,KCNJ11,MAOB,NPY,ZDHHC8,SERPINI1,RGS7,RORB,ATXN1,ARX,SP4,SSTR2,ARHGEF9,CRTC1,NR2E1,NAV2,PAK5,AAAS,JPH3" Mouse Phenotype MP:0000959 abnormal somatic sensory system morphology 3.12E-04 1.00E+00 1.13E-02 1.08E-01 200 737 "DSCAML1,ADRB2,CC2D2A,SEMA6A,ALCAM,BCAR3,ABCD2,APAF1,ASCL1,CHRD,NUMB,ATP2B2,BBS2,NRP2,PROM1,BMPR1B,SYNJ2,BSN,CACNA1D,CACNB2,CAMK2A,BRSK2,RGN,AIFM1,CD86,CDH8,NOG,ASIC3,CHM,LHX2,CLCN3,VAX2,CNGA3,WHRN,SLC4A7,CP,CRY2,LRIG1,PLXNA4,ERC2,CX3CR1,RIPOR2,DCC,HEPH,GSDME,OLIG1,TRAPPC9,CPEB2,SLC12A6,DSCAM,USH1C,WDPCP,EDNRB,HEYL,EFNA2,EGFR,EGR3,C8orf37,EMX2,OLIG2,ENO2,EPHA5,EPHB1,EPS8,ERBB2,ERBB4,ETV1,ADGRV1,EYA1,CACNG2,SEC24B,FGFR1,FGFR3,FOXG1,VTI1B,POMT1,DLL3,TBR1,MEGF11,MEGF10,GABBR1,GABRA5,CHL1,GABRB3,SALL3,ATP8A2,SRRM4,GBX2,GFRA1,GFRA2,KIRREL3,GLRB,GRID1,GRM7,MFSD2A,GUCY1A1,TLX1,IGF1,ZIC5,HES5,KCNJ10,KCNMA1,KIF5C,KIT,L1CAM,LAMA2,LIFR,MAPT,SHC3,MEIS2,MITF,MYCN,MYO6,MYO7A,NDP,NEFH,NEUROD1,NF1,NOS1,NPR2,HCN1,NTRK2,NTRK3,OPA1,CLDN11,PAX6,PDPK1,SEMA5B,TMIE,RETREG1,GPSM2,PMP22,FAT3,POLG,POU3F4,PRKACB,PROX1,PRPH,RELN,PTCH1,PTPN13,STRC,FAT4,FEZF2,RDX,RET,RFX3,RLBP1,RIC8B,ROM1,RORB,RPE65,LGR4,RXRA,ATXN7,ELMOD1,ANKRD6,SLC1A3,SLC4A3,SLC12A2,SOX2,SPATA7,SOX10,SOX11,NMNAT2,MYCBP2,ZNF423,SMOC1,SSTR1,SSTR2,ELOVL4,SYNE2,SEMA4A,CNTN2,AGTPBP1,ZEB1,TRIM2,RPGRIP1L,DICER1,SIRT1,CRB1,ZNF106,THRA,HEY1,TLR4,NR2E1,TP53BP2,WBP2,TUB,UCHL1,VAV2,VLDLR,ZIC2,CRB2,MAP3K12,PCDH15,FZD3,VANGL2,MSRB3,NETO1" Mouse Phenotype MP:0011396 abnormal sleep behavior 3.27E-04 1.00E+00 1.18E-02 1.13E-01 45 127 "PTCHD1,LRRC7,PKP4,ARNTL,ATP1A3,STX16,CACNA1G,C5,CACNA1B,CHRNB2,DLGAP3,CP,CLOCK,CRYM,NRSN1,DBN1,HEYL,MBNL2,NCALD,CLVS1,FOXO3,GABBR1,MCHR1,TPPP,GRIA2,PTPN5,VSIG4,HNMT,HSD17B1,IRF8,KCNA2,KCNC2,MAG,MAP6,NOS1,TMOD2,NALCN,SST,AJAP1,TMEM136,TMEM151B,SIK3,AP4E1,TNFRSF1B,UBE3A" Mouse Phenotype MP:0003894 abnormal Purkinje cell innervation 3.49E-04 1.00E+00 1.25E-02 1.20E-01 9 13 "ATP2B2,CBLN1,SEZ6L2,SEZ6,CACNG2,CHL1,DNER,PTK2,SEZ6L" Mouse Phenotype MP:0008917 abnormal oligodendrocyte physiology 3.73E-04 1.00E+00 1.33E-02 1.28E-01 14 26 "CSF1,TENM4,GALC,GFAP,GJB1,GPM6B,MOG,PLP1,SOX10,NFASC,MLC1,TNFRSF1B,HEPACAM,GJC2" Mouse Phenotype MP:0003460 decreased fear-related response 4.03E-04 1.00E+00 1.44E-02 1.37E-01 22 50 "ADCY8,ADRA1B,APP,ATP1A3,KALRN,CHRNB2,SRGAP3,DRD1,TMEM35A,GABBR1,GABRA1,DISC1,GRIK2,GRIN1,MAP2,GIT1,PTCH1,RYR3,ARX,SP4,ARC,PAK5" Mouse Phenotype MP:0002182 abnormal astrocyte morphology 4.24E-04 1.00E+00 1.50E-02 1.44E-01 64 198 "ABR,NDRG2,ABCD2,ALS2,APP,ASPA,ATP1A3,CANX,CAST,CBS,CD81,CLCN3,CP,CNTNAP2,DCTN1,DRD1,PDCD6IP,EDIL3,EMX2,ERCC2,FGF14,FGFR1,GALC,GFAP,GJB1,HPGDS,GLS,GPM6B,HES5,IL6ST,KCNA1,KCNJ10,KCNQ3,LIFR,NAT8L,MAPT,MOG,NF1,NFE2L2,NTRK2,SERPINE2,PLP1,FA2H,POU3F2,LRRK2,SMPD3,SLC4A3,SNCA,NCDN,MLC1,MGRN1,ATMIN,SLC19A3,ATP13A2,ZNF106,TK2,TSC1,TSC2,CADM1,UCHL1,MGAT5B,GJC2,VANGL2,ST8SIA2" Mouse Phenotype MP:0008779 abnormal maternal behavior 4.32E-04 1.00E+00 1.53E-02 1.46E-01 46 132 "APC,CACNA1A,KALRN,NEURL1,RAB3C,WHRN,RIMS2,DLG4,SHANK1,DSCAM,EFNA3,CSPG5,FYN,GABRA1,GABRB3,GLRB,GNAL,GRIA2,GRIN1,GRM1,NKD1,DOCK7,MAP6,MBP,MEST,MITF,NOS1,NRCAM,OXTR,ABCB1,TMIE,MAGEL2,RAB3A,FIGN,SHANK2,SLC12A2,NPAS3,TBX15,SIRT1,CHST8,THRA,NR2E1,LGI4,FMN2,PCDH15,TMEM163" Mouse Phenotype MP:0001953 respiratory failure 4.37E-04 1.00E+00 1.54E-02 1.47E-01 61 187 "SLC12A5,LGR5,MADD,CASK,CADPS,ATP1A2,CACNA1A,PTBP2,ISPD,SLC32A1,CLIP3,PHF14,DMD,CPEB2,DPH1,CELSR3,EGFR,ERBB2,FOXG1,FOXM1,FLNC,OGA,GAD1,GAD2,NR3C1,IGF1,RBPJ,RIPPLY2,INSM1,RSPO2,MYCN,NELL1,NF1,PAX6,PCSK5,PDGFRA,PKD1,PRRX1,IRX1,PTHLH,PTH1R,ROBO1,ROBO2,FBXW7,RYR1,SOX6,SNAP25,SOX5,SOX10,NMNAT2,KIF1B,MAPK8IP3,JMJD6,SYNE2,ZEB1,SYNE1,HHIP,TIE1,TRPS1,TMEM163,SLC17A6" Mouse Phenotype MP:0008128 abnormal brain internal capsule morphology 4.46E-04 1.00E+00 1.56E-02 1.49E-01 19 41 "PTBP2,CANX,DCLK1,DBN1,DSCAM,EBF1,CELSR3,EPHB1,FOXG1,EVL,DHX35,TUBB2B,PAX6,ARX,MYCBP2,CNTN2,RPGRIP1L,MAP3K12,FZD3" Mouse Phenotype MP:0008027 abnormal spinal cord white matter morphology 4.51E-04 1.00E+00 1.56E-02 1.50E-01 18 38 "NRP2,ISPD,CACNA2D2,CHN1,SLIT2,TENM4,DCC,EDIL3,GALC,ATP8A2,KCNJ10,KLC1,NPR2,ROBO1,ROBO2,SLIT1,UCHL1,ZNF24" Mouse Phenotype MP:0012312 impaired avoidance learning behavior 4.51E-04 1.00E+00 1.56E-02 1.50E-01 18 38 "ADCY8,PTCHD1,ADRA1B,APP,ATP1A3,KALRN,CHRNB2,SRGAP3,GABBR1,GABRA1,DISC1,GRIN1,RYR3,ARX,SORCS3,SP4,WWC1,PAK5" Mouse Phenotype MP:0002969 impaired social transmission of food preference 4.61E-04 1.00E+00 1.59E-02 1.52E-01 8 11 "SYN3,CACNA1B,CAMKK2,TBR1,GRIN1,RASGRF1,SYN1,SYT4" Mouse Phenotype MP:0012296 impaired discrimination learning 4.61E-04 1.00E+00 1.59E-02 1.52E-01 8 11 "SYN3,CACNA1B,CAMKK2,TBR1,GRIN1,RASGRF1,SYN1,SYT4" Mouse Phenotype MP:0009936 abnormal dendritic spine morphology 4.75E-04 1.00E+00 1.62E-02 1.55E-01 31 80 "SLC12A5,LRFN2,KIDINS220,GPR158,LRRC7,TMEM108,NRP2,DLGAP2,ARHGEF6,DBN1,SRGAP3,DLG4,EDIL3,IP6K3,CPT1C,LRRTM3,LRRTM1,GIT1,PCDH9,PDE4B,ZDHHC8,CPEB3,CLSTN1,CCDC88A,SHANK2,CPEB4,KIF21B,TSC2,ELFN1,SPIRE1,SLC17A6" Mouse Phenotype MP:0003993 abnormal ventral spinal root morphology 4.79E-04 1.00E+00 1.62E-02 1.55E-01 12 21 "ALS2,CD86,CACNA2D2,ERBB2,ETV1,NEFH,SCN8A,SNCA,SOX10,AGTPBP1,CUX2,GAN" Mouse Phenotype MP:0002921 abnormal post-tetanic potentiation 4.79E-04 1.00E+00 1.62E-02 1.55E-01 12 21 "ADD2,CYBB,GRIK3,KCNJ10,PDE4B,MAPK9,ATXN7,SLC8A2,STX1A,SYN1,SYN2,SYP" Mouse Phenotype MP:0020525 abnormal thalamus size 4.79E-04 1.00E+00 1.62E-02 1.55E-01 12 21 "APAF1,NUMB,NUMBL,NCOR1,EMX2,FOXG1,DISC1,ZIC5,PAX6,FEZF2,FBXW7,ZNF423" Mouse Phenotype MP:0020167 abnormal vertical activity 4.90E-04 1.00E+00 1.65E-02 1.58E-01 73 233 "ADCY5,SLC12A5,ADRA1D,ABCD2,ALK,SPTBN4,ASPA,ATM,CHRNA4,NRXN2,TPP1,CNR1,CLOCK,FEZ1,PDE4DIP,CYBB,GPRASP1,DGKB,BRINP1,DCTN1,DLG4,DRD1,EFNA2,EFNA3,SEZ6,CACNG2,FLNC,GAA,GABRB3,GAD2,DISC1,CPLX2,PCSK1N,GRIA1,GRIA4,GRIN1,GRIN2C,GRIN2D,MFSD2A,PSIP1,VSIG4,HTR2A,LRRTM1,KCNJ11,L1CAM,NAT8L,NPY,NRCAM,OGG1,PDE4B,TMOD2,NLGN3,PCDH18,MAGEL2,FA2H,KHDRBS2,RGS4,ACER3,SH3GL2,ARX,SNAP25,SP4,BEX1,SSTR2,DDHD2,AP4E1,TSC1,TSC2,TOM1L2,ELFN1,GJC2,CERS6,VANGL2" Mouse Phenotype MP:0000825 dilated lateral ventricles 5.26E-04 1.00E+00 1.76E-02 1.69E-01 27 67 "ARHGAP5,CDK5R1,E2F5,AK8,HSF2,ZIC5,KCNJ10,L1CAM,MDM4,MSI1,MYO9A,NEK1,NFIA,NFIX,OPA1,OPHN1,PKD1,MBOAT7,HYDIN,ATAT1,MYCBP2,ZNF423,MAPK8IP3,NR2E1,MAP3K12,FZD3,ST8SIA2" Mouse Phenotype MP:0009751 enhanced behavioral response to alcohol 5.45E-04 1.00E+00 1.82E-02 1.74E-01 10 16 "UNC79,ALK,CACNA1B,TAOK2,PPP1R1B,FYN,GABRB1,KCNC1,PRKCG,SLC6A1" Mouse Phenotype MP:0005498 hyporesponsive to tactile stimuli 5.63E-04 1.00E+00 1.87E-02 1.79E-01 22 51 "ADCY8,SLC12A5,PRX,MADD,KIF1A,BBS2,CACNA1A,CACNA1B,BRSK2,CCKBR,ASIC3,FLNC,BRSK1,GABBR1,PCSK2,KCNIP3,SLC6A9,SPP1,ERBIN,TACR1,TLR4,TSC1" Mouse Phenotype MP:0008281 abnormal hippocampus size 5.72E-04 1.00E+00 1.89E-02 1.81E-01 26 64 "BBS2,PTBP2,CD81,CLCN3,DRD1,PDCD6IP,DYRK1A,EMX2,FOXG1,AK8,CPLX2,HSF2,LRRTM1,KCNA1,MAPT,MBOAT7,PACSIN1,RGS4,SLC6A8,CDK5RAP2,SOX2,SOX11,SP2,AGTPBP1,NR2E1,UBE3B" Mouse Phenotype MP:0011188 increased erythrocyte protoporphyrin level 5.74E-04 1.00E+00 1.89E-02 1.81E-01 7 9 "ANK1,HEPH,FECH,KIT,KITLG,SLC11A2,SPTB" Mouse Phenotype MP:0008535 enlarged lateral ventricles 5.77E-04 1.00E+00 1.90E-02 1.81E-01 36 98 "ASPA,NUMB,BBS2,WASF1,PTBP2,DCLK1,NUMBL,CLCN3,CSF1R,CDON,DRD1,PDCD6IP,DSCAM,PRMT5,VTI1B,CHL1,HSF2,PPM1L,BLOC1S2,NFIX,NRDC,PLXNB1,POU3F2,RGS4,ZC3H14,ATXN1,SOX2,MYCBP2,ZNF423,NPAS3,CNTN2,AP4E1,TSC1,ZIC2,FZD3,VANGL2" Mouse Phenotype MP:0008814 decreased nerve conduction velocity 5.95E-04 1.00E+00 1.95E-02 1.86E-01 21 48 "CNTNAP1,PRX,CACNB4,CANX,CD86,LAMA2,MBP,NRCAM,PLEC,PMP2,PMP22,SH3TC2,GLDN,SCN8A,SIRT2,SOX10,NFASC,ERBIN,SEPT8,FGD4,TNR" Mouse Phenotype MP:0011084 "lethality at weaning, incomplete penetrance" 6.24E-04 1.00E+00 2.03E-02 1.95E-01 20 45 "CNTNAP1,HCN2,CLCN3,SNAP91,DNM2,FGFR3,JPH4,ATP8A2,HPSE2,KIF5A,KIT,NFE2L2,NFIX,WLS,SOX10,ZNF423,STX1A,PLCB1,HEY2,JPH3" Mouse Phenotype MP:0003106 abnormal fear-related response 6.32E-04 1.00E+00 2.05E-02 1.96E-01 28 71 "SLITRK1,ADCY8,ADRA1B,APP,ATP1A3,CDK5R1,KALRN,SHISA7,CHRNB2,LYPD1,SRGAP3,DRD1,TMEM35A,FYN,GABBR1,GABRA1,DISC1,GLUL,GRIK2,GRIN1,MAP2,GIT1,PTCH1,RYR3,ARX,SP4,ARC,PAK5" Mouse Phenotype MP:0003486 abnormal channel response intensity 6.42E-04 1.00E+00 2.08E-02 1.98E-01 6 7 "KCNT1,HCN2,CACNA1E,CACNA2D1,IL6ST,KCNT2" Mouse Phenotype MP:0009940 abnormal hippocampus pyramidal cell morphology 6.92E-04 1.00E+00 2.23E-02 2.13E-01 27 68 "CADPS,ATP1A3,CDK5R1,KALRN,CD81,CLCN3,CRMP1,CSF1,CTNND1,DLG4,SHANK1,EFNA3,ABI2,APC2,FGF14,FOXG1,DPYSL4,FYN,DCLK2,MAPT,AFDN,CPEB3,SLC1A2,SYN1,TSC1,TSC2,TUBA1A" Mouse Phenotype MP:0001458 abnormal object recognition memory 7.02E-04 1.00E+00 2.24E-02 2.15E-01 32 85 "APP,ATP1A3,WASF1,CAMK2A,CAMK2B,NCOR1,SRGAP3,RCAN1,RCAN2,FGF13,BAIAP2,GABBR1,JPH4,GRIA4,GRIN1,MAPT,GIT1,PCDH9,PDE4B,RGS4,CARF,SLC6A1,SLC6A8,SLC8A2,CCDC88A,SNAP25,TNIK,ARC,SYN2,THRA,SLC17A7,JPH3" Mouse Phenotype MP:0003360 abnormal depression-related behavior 7.06E-04 1.00E+00 2.24E-02 2.15E-01 45 131 "SLITRK1,MTA3,GPR158,APP,B3GALT2,ADGRB2,RGS9,HCN2,HAP1,CAMK2A,CNR1,MAGED1,ZNF521,CSF1R,SIRPA,SLC12A6,DRD1,FGF13,PDLIM5,GABBR1,GAD2,DISC1,PCDH17,PPARGC1A,DHRS4,GPR26,NR3C1,HNF4G,KCNH1,NOS1,HCN1,P2RX7,PDE1B,PTPRG,ELMOD1,EPC1,STX1A,TAC1,CRTC1,CSMD1,TSC2,UBE3A,UCHL1,SLC17A7,FZD3" Mouse Phenotype MP:0004631 abnormal auditory cortex morphology 7.06E-04 1.00E+00 2.24E-02 2.15E-01 5 5 "SPTBN4,ATP2B2,ARHGAP33,CHRM1,TUBA1A" Mouse Phenotype MP:0002733 abnormal thermal nociception 7.56E-04 1.00E+00 2.40E-02 2.29E-01 52 157 "SLC12A5,ADORA1,ADORA2A,KCNT1,PRX,ATP1A3,HCN2,CDK5R1,CACNA1A,CACNA1B,P2RX6,CDH8,ADGRG1,ASIC3,TPP1,CNR1,WHRN,CNTNAP2,FRMPD4,HDAC4,GIT2,KMT5B,SEMA6C,GABRA4,GNAO1,PRLHR,GRIA4,GRIK5,GRM5,KCNA1,KCNA6,KCND2,L1CAM,OPRL1,PCSK2,PIRT,PDYN,RETREG1,PRKAR1B,PTPRZ1,KCNIP3,ARX,MYCBP2,ZNF106,TLR4,NR2C2,NTSR2,UCHL1,KCNT2,NAV2,SLC17A6,RNF170" Mouse Phenotype MP:0000866 cerebellum vermis hypoplasia 7.86E-04 1.00E+00 2.48E-02 2.37E-01 9 14 "CACNA2D2,EN2,ZIC4,GBX2,L1CAM,FBXW7,ZNF423,ZIC1,PDSS2" Mouse Phenotype MP:0003043 hypoalgesia 7.94E-04 1.00E+00 2.50E-02 2.39E-01 53 161 "ADCY8,SLC12A5,ADORA2A,PRX,MADD,ATP1A3,KIF1A,BBS2,HCN2,CDK5R1,CACNA1A,CACNA1B,BRSK2,CCKBR,P2RX6,ASIC3,TPP1,CNR1,WHRN,HDAC4,GIT2,EDNRB,KMT5B,FLNC,BRSK1,GABBR1,PRLHR,GRIA4,GRIK1,GRIK5,GRM5,MAP4K5,KCNA6,PCSK2,PIRT,RETREG1,PRKAR1B,PTPRZ1,KCNIP3,SLC6A9,SPP1,ERBIN,TAC1,TACR1,ZNF106,TLR4,NR2C2,NTSR2,TSC1,UCHL1,NAV2,SLC17A6,RNF170" Mouse Phenotype MP:0002196 absent corpus callosum 8.29E-04 1.00E+00 2.59E-02 2.48E-01 21 49 "MRTFA,APBB1,APBB2,APP,NUMB,PTBP2,DCLK1,NUMBL,NIPBL,DCC,TUBB3,FOXG1,KIF3A,TUBB2B,NFIA,PLXNB1,FEZF2,DRAXIN,ZNF423,RPGRIP1L,PRDM8" Mouse Phenotype MP:0020157 abnormal behavioral response to alcohol 8.45E-04 1.00E+00 2.62E-02 2.51E-01 12 22 "ADORA2A,UNC79,ALK,CACNA1B,TAOK2,PPP1R1B,FYN,GABRB1,GRIN1,KCNC1,PRKCG,SLC6A1" Mouse Phenotype MP:0011617 abnormal habituation 8.45E-04 1.00E+00 2.62E-02 2.51E-01 12 22 "SLC12A5,ATP1A3,CHRNB2,TAOK2,ARHGAP32,ENO2,GABBR1,NAT8L,CCDC88A,TCF4,TMEM163,CERS6" Mouse Phenotype MP:0001504 abnormal posture 8.73E-04 1.00E+00 2.70E-02 2.58E-01 83 276 "ACHE,SLC12A5,MTA3,ABCD2,CNTNAP1,APC,MIER1,CASK,SPTBN4,ARNTL,ATP2B2,KIF1A,HCN2,BCS1L,CACNA1A,CACNB4,CDO1,CLCN3,TPP1,CNTN1,GAL3ST1,ZNF521,SLC32A1,DMD,DNM1,SLC12A6,DRD1,DSCAM,USH1C,EGR3,OLIG2,GPHN,ERBB2,GORAB,FGF14,FGFR1,GABBR1,GABRA1,GABRG2,ATP8A2,CPLX2,GLRB,GNAS,GPM6B,GRIA2,GRM1,PSIP1,SMAP1,ZIC5,ITGAV,KCNA1,KCNA2,KCNJ10,KIF5A,MYO5A,MYO7A,NF1,PBX1,PLP1,RELN,PEX2,RYR1,SCN8A,ELMOD1,SLC6A9,SNCA,SOX10,NMNAT2,MYCBP2,NFASC,VAMP1,CAMTA1,RBFOX2,TRPS1,TSC1,UBE3A,FRRS1L,REEP1,SLC17A7,SLC17A6,PDSS2,KAT6A,GAN" Mouse Phenotype MP:0004948 abnormal neuronal precursor proliferation 8.90E-04 1.00E+00 2.74E-02 2.62E-01 36 100 "ASCL1,COPB2,GPR37L1,CNR1,CRMP1,NCOR2,KIF26A,CDON,EML1,EMX2,PRMT5,FOXG1,GAD1,GAP43,GFRA1,GLI2,KDM2B,TUBB2B,BLOC1S2,MYCN,NAP1L1,RCOR2,NF1,PAX6,PLXNB1,PTCH1,TET1,SMARCC2,SOX1,SOX2,SOX11,SP2,CUX2,NR2E1,TP53BP2,GDPD5" Mouse Phenotype MP:0011616 abnormal nonassociative learning 9.35E-04 1.00E+00 2.87E-02 2.74E-01 13 25 "SLC12A5,ATP1A3,CDK5R1,CHRNB2,TAOK2,ARHGAP32,ENO2,GABBR1,NAT8L,CCDC88A,TCF4,TMEM163,CERS6" Mouse Phenotype MP:0001963 abnormal hearing physiology 9.71E-04 1.00E+00 2.97E-02 2.84E-01 128 456 "ASIC2,PTCHD1,AQP4,SPTBN4,ASPA,NUMB,ATP2B2,KIF1A,ADGRB1,MPDZ,HCN2,SYNJ2,C5,BSN,CA8,CACNA1D,HIP1R,FMNL3,RGN,NOG,NUMBL,ASIC3,NIPBL,WHRN,COL9A1,COL9A2,COL11A2,SLC4A7,CS,CSF1,CSF1R,LRIG1,RIPOR2,RIMS3,SIRPA,GSDME,FAM107B,DLX1,DMD,DNM1,SLC12A6,USH1C,EDIL3,EDNRA,EDNRB,EMX2,ADGRV1,EYA1,CACNG2,ACSL4,FGFR1,FGFR3,GABRA5,GABRB3,ATP8A2,SRRM4,CPLX1,ALDH1L1,NTNG2,GPM6B,GRID1,PACSIN2,IGF1,KCNA1,KCNJ10,KCNMA1,KIT,LAMA2,MAG,MBP,MITF,MYO6,MYO7A,NDP,NEUROD1,NTRK2,OPA1,OPRL1,CLDN11,ABCB1,TMIE,GPSM2,PLP1,PMP22,EPB41L4B,POLG,POU3F4,PTN,TMEM145,STRC,ENOX1,RDX,FIGN,RFX3,GSTCD,RPL38,SALL1,SCN8A,ELMOD1,FBXO11,CCDC92,SLC1A3,SLC12A2,SNAP25,WDTC1,SOX2,ZHX3,TSPYL2,LRRC4,ROBO3,AGTPBP1,ZEB1,SIRT1,AP4E1,THRA,WBP2,TUB,KLC2,ZNF24,ZNF142,FTSJ1,PCDH15,UBE3B,VANGL2,MSRB3,NHSL1,AP3B2,SLC4A10" Mouse Phenotype MP:0020468 abnormal circadian behavior period 9.97E-04 1.00E+00 3.04E-02 2.90E-01 17 37 "ADCYAP1R1,ARNTL,ATP1A3,USP2,CIART,CNGA3,MAGED1,CLOCK,CRY2,NCOR1,CSNK1E,NR1D2,FYN,NCAM1,RAB3A,ANKFN1,VGF" Mouse Phenotype MP:0010170 abnormal glial cell apoptosis 1.06E-03 1.00E+00 3.23E-02 3.09E-01 10 17 "TENM4,GALC,GJB1,GPM6B,MOG,TREM2,PLP1,TLR4,TNFRSF1B,GJC2" Mouse Phenotype MP:0000852 small cerebellum 1.09E-03 1.00E+00 3.31E-02 3.16E-01 53 163 "ANK3,CNTNAP1,APP,NUMB,ASTN1,ATP2B2,CDK5R1,CDK5R2,CACNA1A,AIFM1,DCLK1,CACNA2D2,PLAA,CNTN1,DNM1L,E2F6,EDIL3,EGFR,EN2,EPB41L1,EPB41L2,ZIC4,DISC1,GLI2,CIT,TUBB2B,L1CAM,MDM4,MYCN,NEUROD1,NEUROD2,NRCAM,OPA1,HYDIN,RELN,LAMA1,PEX2,KHDRBS2,FBXW7,SCN8A,SOX11,ZNF423,CAMTA1,AGTPBP1,RPGRIP1L,RBFOX2,TRIO,UBE3A,VLDLR,ZIC1,LRP8,PDSS2,ST8SIA2" Mouse Phenotype MP:0008284 abnormal hippocampus pyramidal cell layer 1.11E-03 1.00E+00 3.31E-02 3.17E-01 32 87 "MRTFA,CADPS,ATP1A3,CDK5R1,KALRN,CD81,CLCN3,CRMP1,CSF1,CTNND1,DLG4,SHANK1,EFNA3,ABI2,APC2,FGF14,FOXG1,DPYSL4,FYN,DCLK2,MAPT,AFDN,NCAM1,RELN,CPEB3,SLC1A2,SYN1,TNR,TSC1,TSC2,LRP8,TUBA1A" Mouse Phenotype MP:0004103 abnormal ventral striatum morphology 1.12E-03 1.00E+00 3.31E-02 3.17E-01 8 12 "CD81,CLOCK,EBF1,RELN,ARX,SOX1,MYCBP2,CNTN2" Mouse Phenotype MP:0030735 abnormal glutamic acid level 1.12E-03 1.00E+00 3.31E-02 3.17E-01 8 12 "ASPA,CACNA1A,DBT,ELAVL3,ELAVL4,PRODH,DGLUCY,REEP1" Mouse Phenotype MP:0004716 abnormal cochlear nerve morphology 1.12E-03 1.00E+00 3.31E-02 3.17E-01 8 12 "ATP2B2,CACNA1D,GABRB3,IGF1,KCNJ10,LAMA2,NTRK2,NTRK3" Mouse Phenotype MP:0010698 abnormal impulsive behavior control 1.12E-03 1.00E+00 3.31E-02 3.17E-01 8 12 "CNR1,ZNF521,ENO2,DISC1,JAKMIP1,PRKCG,SNAP25,ELFN1" Mouse Phenotype MP:0000832 abnormal thalamus morphology 1.17E-03 1.00E+00 3.45E-02 3.30E-01 27 70 "APAF1,NUMB,DCLK1,NUMBL,CHRNB2,NCOR1,DYRK1A,EDIL3,EFNA2,EFNA3,EMX2,CACNG2,FOXG1,DISC1,GBX2,ZIC5,PAX6,FEZF2,FBXW7,ARX,SLC20A2,SOX2,MYCBP2,ZNF423,MAPK8IP3,AGTPBP1,ZIC3" Mouse Phenotype MP:0005369 muscle phenotype 1.34E-03 1.00E+00 3.95E-02 3.78E-01 386 1550 "ACADM,ASIC2,ACHE,ARID1A,PLEKHG5,ADCY6,ADORA2A,PTCHD1,ADRA1D,ADRA1B,ADRB2,AGT,WDR35,PLA2G6,LTBP4,MRTFA,BIN1,ANK1,CNTNAP1,GAS7,ALS2,APP,SPTBN4,ARNTL,ARRB1,ASPA,ASPH,PTCH2,CHRD,TMEM108,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,ATP2B1,BACH1,NRP2,BID,CFLAR,NAE1,SGCE,BSN,WASF1,FOXK1,CACNA1A,CACNA2D1,CACNB2,CACNB4,CACNG1,KALRN,CAMK2D,CAPN3,CBS,KRIT1,AIFM1,CD86,ARHGEF1,SCARB1,CDH2,NOG,CACNA2D2,CFL2,CHGA,CHN1,CHRM4,CHRNB2,PLAA,PPT2,CLCN3,CLU,TPP1,QKI,TMEM184B,NIPBL,AKAP6,SLC4A7,PREPL,CREM,AKAP12,CRY2,SLC32A1,NCOR1,NCOR2,CLIP3,CSF1,ATRNL1,CST3,APPL1,CTH,GPSM1,CX3CR1,CYBB,HDAC9,HDAC4,KIF26A,MAML1,DCTN1,MED24,BLOC1S6,DMD,DMPK,TRAPPC9,DNM2,SLC12A6,DRD1,ABI1,DSCAM,RCAN1,GNE,DTNA,DNM1L,ABCC9,EDIL3,EDN1,EDNRA,EDNRB,EEF1A2,HEYL,APH1A,EGFR,MBNL2,EGR3,PLEKHA1,SRPK3,EML1,CALCRL,OLIG2,RCAN2,ERBB2,ERBB4,SPEG,ETV1,EYA1,MRVI1,ECSIT,F3,PTK2B,EFEMP1,FKTN,FGF14,FGFR1,PRKAG2,FHL1,FOXG1,CAP2,FOXM1,EVL,FLNC,FLT1,NBEA,POMT1,PDLIM5,DLL3,DOT1L,GAA,GAB1,GABRA1,GAD2,ZMYND11,GALC,NEK6,INPP5K,MYOZ2,GATM,MSTN,GFAP,GFRA1,GFRA2,FREM1,USP19,GHR,PPARGC1A,GLI2,GLRB,GNAS,PRRC2B,GPM6B,LPAR4,RAPGEF4,GRB10,RAPGEF1,NR3C1,ATE1,GRM1,GRM7,CIT,KIF3A,RNF165,BVES,ADAMTS6,GUCY1A1,GUCY1B1,HAS2,HBA1,CPT1C,HTR2A,ATCAY,MYLK2,IGF1,RBPJ,RIPPLY2,ITGA7,ITGAV,KCNA1,KCNC1,KCNC2,KCNH2,KCNJ11,KCNMA1,KIT,LAMA2,LAMP2,STMN1,LIMS1,SMAD1,SMAD9,MAPT,MBNL1,MDM4,MEF2C,MEST,MOG,CTNNA3,MYCN,MYH6,MYH7,MYO5A,MYO6,MYT1,NACA,NF1,NODAL,NOS1,NPPA,NPR2,NRCAM,DDR2,OLR1,OPA1,PAX6,PBX1,PCSK1,PDGFRA,PDPK1,PIK3R1,PKD1,TMEM38A,PLEC,PLIN1,FXYD1,PLP1,PMP22,SCHIP1,MAGEL2,POLG,PPARA,MED1,PPP3CA,PPP3CB,PRKAB2,MAPK7,MAPK8,MAPK9,HYDIN,PROX1,RELN,SNRK,QRICH1,PTCH1,PTK2,PTPRB,PEX5,PYGM,SH3TC2,ATG16L1,RET,RFX3,KIF7,SETD5,MYH14,ROBO1,ROBO2,TMEM100,RPS6KA2,WLS,RXRA,RXRG,RYR1,RYR3,ATXN1,ATXN7,SCN8A,FNIP1,SH3BP2,ARX,FUZ,FHOD3,SLC4A3,SMTN,LIMS2,SLC6A8,SLC6A9,SLC8A1,SLC8A3,MTERF2,EPC1,SMARCA4,SNAP25,LMBRD1,SOX1,SOX2,SOX11,SOX15,KDM3A,SP4,NMNAT2,MYCBP2,SPP1,ARHGAP26,SPTAN1,SPTB,KIF1B,MESP1,SULF2,JMJD6,SYNE2,SYT1,ATP11A,TAL1,AGTPBP1,MGRN1,TBX15,TCF7L2,ZEB1,RPGRIP1L,SYNE1,ARHGEF12,HIF3A,TEK,DICER1,SIRT1,ZFPM2,AP4E1,TGFBR3,ZNF106,THBS4,THRA,ENHO,MTMR14,TIE1,HEY1,TK2,TLL2,TLR4,HEY2,LRRC8A,TMOD1,DAAM2,TNFRSF1B,TNNT1,TP53BP2,TPM3,TRIO,TRPM2,TSC1,ANO5,TSC2,TTPA,HIRA,FLRT2,VAV2,RICTOR,ZIC1,SPHK2,CELF4,ZFAND5,SYNC,WNK1,PCDH15,PDSS2,EPM2A,RNF170,SSPN,FXR1,GAN" Mouse Phenotype MP:0002566 abnormal sexual interaction 1.38E-03 1.00E+00 4.05E-02 3.87E-01 30 81 "DDO,SPTBN4,CACNA2D2,CSF1,CSF1R,DLL3,GABRB3,CPLX1,KIRREL3,GRIA1,GRIA2,GRIN1,GRM1,KCNA1,LAMA2,MAPT,NOS1,NRCAM,SERPINE2,PMP22,RELN,RORB,SAFB,SHANK2,SLC12A2,SOX1,SP4,CRTC1,TSC1,LGI4" Mouse Phenotype MP:0001731 abnormal postnatal growth 1.40E-03 1.00E+00 4.09E-02 3.91E-01 259 1006 "ACHE,AXIN2,SLC12A5,FZD9,AGT,CC2D2A,ALK,ANK1,ANXA7,APC,GPAM,AQP4,CASK,ARNTL,DACT3,NUMB,ATM,SLC4A4,ATP2B2,BCS1L,NRP2,BLM,SYNJ1,WASF1,DDR1,CACNB4,KALRN,HAP1,PTBP2,CAMK2B,HIP1R,RUNX1T1,AIFM1,LGI1,CDO1,NUMBL,CACNA2D2,CFL2,CHGA,CHRNB2,KMT2C,CLCN3,NIPBL,CNR1,COL11A2,SMARCAL1,ZNF521,PREPL,CRHBP,SH2B1,CSF1,CSF1R,PNPLA8,CTH,HDAC9,KIF26A,RASSF2,MAML1,IP6K1,BRINP1,DBI,HP1BP3,MAGI2,SNAP91,SV2B,SV2A,KIF19,DMD,DNM2,DMTF1,DRD1,DSCAM,DTNA,ABCC9,E2F6,EDIL3,EDNRB,EEF1A2,EGFR,EN2,RCAN2,SLC43A2,ERBB2,ERCC2,APC2,CACNG2,RACK1,ZMYND10,FKTN,FDFT1,FGFR3,MAD2L2,SUCO,CAP2,FOXF2,STAMBP,GABRG2,GALC,ATP8A2,ACSS1,GBX2,GCK,GGT5,GHR,GLUL,GNAS,GNG3,FERMT2,GPD2,MCHR1,GRIA2,GRIN1,ATE1,KIF3A,RNF165,GUCY1B1,HPSE2,IGF1,NKD1,RBPJ,INPP5B,ITGA7,ITPKB,KCNA2,KCNC1,KCNJ10,KCNJ11,KCNMA1,KIF5A,KIT,L1CAM,LAMA2,LIG4,LIMS1,MAPT,AQP11,KITLG,MMP16,ADAM22,MSRA,MYCN,MYO5A,MYO7A,MYO9A,NACA,NEUROD1,NEUROD2,NF1,NFIX,NKX2-2,NPR2,SLC11A2,NRCAM,NTRK2,DDR2,OCRL,PAH,PAX6,PCSK1,NLGN3,PIK3C2A,PKD1,SNX10,PLEC,FTO,EPN1,PMP22,POU3F2,MED1,HYDIN,RELN,PTCH1,PTHLH,PTH1R,PEX2,PEX5,RASGRF1,FEZF2,RET,FIGN,RFX3,RGS7,RGS10,RPL38,LGR4,SOX8,WLS,SATB1,ATXN1,SLC30A10,ITSN1,SH3GL2,ARX,FERMT1,SLC1A2,EPN2,SMTN,LIMS2,CCDC88A,SLC12A2,SLC14A1,SNCA,MBD5,SNRPN,SOX3,SOX10,SP2,SP4,NFASC,ITPRID2,SMOC1,SULF2,MLC1,PLCB1,TBX15,TCF4,ZEB1,TCF12,USP22,SYNE1,FRYL,TF,DICER1,SIRT1,THRA,TJP1,TK2,NR2E1,HEY2,LRRC8A,TP53BP1,TRH,TRIO,TSN,TSC1,TSC2,TMEFF2,SGK3,UBE3A,UGT8,LMF1,CLIP2,NSD2,PORCN,RICTOR,XRCC4,LGI4,ZIC1,ZIC3,SMARCAD1,SLC30A4,PCDH15,SLC17A7,SNX27,TMEM163,NLRP3,FXR1,IFT88,SLC4A10" Mouse Phenotype MP:0001408 stereotypic behavior 1.43E-03 1.00E+00 4.18E-02 3.99E-01 67 218 "ACHE,LRFN2,PPFIA2,APP,SPTBN4,NUMB,ATP2B2,HCN2,SGCE,CACNA1A,CACNB4,NUMBL,CHN1,CLCN3,NIPBL,CNTN1,WHRN,LRIG1,FEZ1,CNTNAP2,ARHGAP32,BRINP1,DLG4,OLIG1,USH1C,EDIL3,EYA1,CACNG2,FOXG1,GABRB3,SRRM4,PCSK1N,GNAO1,GRIN1,KCNMA1,MAP6,MAPT,MYO5A,MYO6,MYO7A,NEUROD1,NEUROD2,NF1,NFE2L2,NTRK2,NLGN3,TMIE,JAKMIP1,POU3F4,FIGN,SCN8A,ELMOD1,SHANK2,SLC12A2,ANKFN1,SOX2,NPAS3,SST,ADGRL3,ZEB1,TTPA,ANKS1B,SLC30A4,PRDM8,PCDH15,SLC17A6,VANGL2" Mouse Phenotype MP:0008947 increased neuron number 1.46E-03 1.00E+00 4.23E-02 4.05E-01 37 106 "DSCAML1,UNC5A,APAF1,ASCL1,ATP2B2,NOG,RIMS2,GSDME,DSCAM,HEYL,EMX2,GPHN,ETV1,EYA1,FGF13,FGFR1,FGFR3,FOXG1,FYN,GLI2,HES5,KIF5C,MAPT,NEUROD1,NKX2-2,PTCH1,KIF7,RORB,IFT122,SPP1,CUX2,CRB1,HEY1,RBFOX2,CRB2,MAP3K12,VANGL2" Mouse Phenotype MP:0005551 abnormal eye electrophysiology 1.49E-03 1.00E+00 4.30E-02 4.12E-01 69 226 "ASIC2,CC2D2A,CNTNAP1,AQP4,SLC7A14,ARNTL,BBS2,RGS11,RGS9,PROM1,CACNB2,CACNB4,AIFM1,ASIC3,CHM,CHRNB2,CLCN3,CNGA3,WHRN,SLC4A7,CSF1,ERC2,SV2B,GRIN3A,DMD,DRD1,DSCAM,C8orf37,CDHR1,ADGRV1,FOXG1,RGPD5,ATP8A2,GNAO1,GPM6B,HAPLN2,KCNJ10,MITF,MYO6,MYO7A,NEUROD1,NPTX1,NPTX2,NTRK2,OPA1,CLDN11,SEMA5B,PLP1,SDK2,RELN,LAMA1,RGR,RGS7,ROM1,RORB,RPE65,RXRA,SCN8A,SLC4A3,SPATA7,SSTR1,ELOVL4,SYNE2,SEMA4A,AGTPBP1,NR2E1,TTPA,BEST1,CRB2" Mouse Phenotype MP:0001489 decreased startle reflex 1.52E-03 1.00E+00 4.35E-02 4.16E-01 43 128 "SLITRK1,ADRA1D,ASPA,ATP2B2,BBS2,CACNA1B,KALRN,CAST,USP2,COX4I1,DLG4,EDNRA,EFNA2,EFNA3,ADGRV1,CACNG2,FOXO3,EVL,DISC1,ATP8A2,GATM,GNAO1,GRIA4,CACFD1,CPT1C,MAG,MBP,MYO6,MYO7A,TMOD2,NLGN3,PTPRG,SCN8A,ELMOD1,FBXO11,PLCB1,TCF4,CSMD1,NTSR2,RNF103,NAV2,TMEM163,FZD3" Mouse Phenotype MP:0006254 thin cerebral cortex 1.52E-03 1.00E+00 4.35E-02 4.16E-01 43 128 "ARHGAP5,ATM,BBS2,WASF1,HAP1,PTBP2,AIFM1,DCLK1,ARHGAP33,CDON,PDCD6IP,DSCAM,EGFR,ZMYND10,PRMT5,FOXG1,SMC2,GAD1,DISC1,GFAP,TUBB2B,LRRTM1,KCNJ10,L1CAM,LIG4,BLOC1S2,RCOR2,NF1,NRDC,OPHN1,PAX6,PCDH9,PLXNB1,HYDIN,PRRT2,RGS4,CDK5RAP2,SOX1,SOX11,XRCC4,ZIC2,FZD3,ST8SIA2" Mouse Phenotype MP:0001425 abnormal alcohol consumption 1.53E-03 1.00E+00 4.35E-02 4.16E-01 15 32 "UNC79,ALK,MPDZ,CACNA1B,TAOK2,EPS8,PPP1R1B,GABRB1,GNAS,GPR26,GRIN1,GRM5,NOS1,PRKCG,SLC6A1" Mouse Phenotype MP:0008916 abnormal astrocyte physiology 1.53E-03 1.00E+00 4.35E-02 4.16E-01 15 32 "ABR,NDRG2,PLA2G6,ANXA7,AQP4,CDH18,CP,MEGF10,GFAP,GRM3,KCNJ10,NF1,PLP1,MLC1,TSC1" Mouse Phenotype MP:0009749 enhanced behavioral response to addictive substance 1.54E-03 1.00E+00 4.37E-02 4.18E-01 21 51 "UNC79,ALK,ATP1A1,ATP1A3,CACNA1B,CCKBR,CHRM4,CHRNA4,TAOK2,CLOCK,DLG4,PPP1R1B,FYN,GABRB1,KCNC1,NOS1,NTRK2,PRKCG,PPP1R9A,SLC6A1,ADGRL3" Mouse Phenotype MP:0001499 abnormal kindling response 1.58E-03 1.00E+00 4.47E-02 4.28E-01 9 15 "ATP1A3,CREM,DNM1,FGF13,GFRA2,GNAO1,NTRK2,SLC1A3,SZT2" Mouse Phenotype MP:0009967 abnormal neuron proliferation 1.59E-03 1.00E+00 4.47E-02 4.28E-01 47 143 "ASCL1,HAP1,COPB2,GPR37L1,CNR1,CRMP1,NCOR2,KIF26A,MAML1,CDON,EDIL3,EML1,EMX2,EN2,CEND1,PRMT5,FOXG1,GAD1,GAP43,GFRA1,GLI2,KDM2B,TUBB2B,BLOC1S2,MYCN,NAP1L1,NCAM2,RCOR2,NF1,PAX6,PLXNB1,PTCH1,SLC6A8,TET1,SMARCC2,CDK5RAP2,SOX1,SOX2,SOX10,SOX11,SP2,ZNF423,CUX2,NR2E1,TP53BP2,RBFOX2,GDPD5" Mouse Phenotype MP:0003224 neuron degeneration 1.64E-03 1.00E+00 4.60E-02 4.39E-01 112 397 "ABCD2,ANK1,ANK3,APAF1,APP,ATM,ATP2B2,KIF1A,PROM1,SYNJ2,CACNA1A,CACNA1D,CACNB2,PTBP2,AIFM1,CACNA2D2,ASIC3,CHM,CLCN3,TPP1,QKI,CNGA3,WHRN,SLC4A7,CP,CSF1R,CX3CR1,DCTN1,HEPH,SLC12A6,USH1C,EDIL3,EDNRB,EEF1A2,EGR3,OLIG2,GPHN,ERCC2,ADGRV1,FGF14,FOXG1,FLT1,STAMBP,GABRA5,GABRB3,B4GALNT1,ATP8A2,SRRM4,GFAP,GFRA1,PPARGC1A,GPM6B,GPR37,GRIA2,GRID1,GRM7,HPCA,ATCAY,KCNJ10,KIT,MAPT,MITF,AFF1,MSR1,MYO6,MYO7A,NDP,NF1,NTRK3,OPA1,CLDN11,ABCB1,TMIE,RETREG1,PLP1,ANKRD16,POLG,POU3F4,RELN,RDX,RFX3,ROM1,RORB,RPE65,ACER3,LGR4,ATXN1,ATXN7,SCN8A,SLC1A3,SNCA,SOX2,SPATA7,SOX10,ELOVL4,STXBP1,MTCL1,CAMTA1,AGTPBP1,TRIM2,ZNF106,TSC2,TUB,UCHL1,VAV2,VLDLR,LRP8,PCDH15,PDSS2,EPM2A,GJC2,MSRB3" Mouse Phenotype MP:0003878 abnormal ear physiology 1.68E-03 1.00E+00 4.72E-02 4.51E-01 138 503 "ASIC2,SLC12A5,PTCHD1,AQP4,SPTBN4,ASPA,NUMB,ATP2B2,KIF1A,ADGRB1,MPDZ,HCN2,SYNJ2,C5,BSN,CA8,CACNA1D,CALB1,HIP1R,FMNL3,RGN,NOG,NUMBL,ASIC3,QKI,NIPBL,WHRN,COL9A1,COL9A2,COL11A2,SLC4A7,CS,CSF1,CSF1R,LRIG1,RIPOR2,RIMS3,SIRPA,BLOC1S6,GSDME,FAM107B,DLX1,DMD,DNM1,SLC12A6,USH1C,EDIL3,EDNRA,EDNRB,EMX2,ADGRV1,EYA1,CACNG2,ACSL4,FGFR1,FGFR3,GABRA5,GABRB3,ATP8A2,SRRM4,CPLX1,ALDH1L1,NTNG2,GPM6B,GRID1,PACSIN2,IGF1,JAK1,KCNA1,KCNJ10,KCNMA1,KIT,LAMA2,MAG,MBP,MITF,MYO6,MYO7A,NDP,NEUROD1,NTRK2,ODF2,OPA1,OPRL1,CLDN11,ABCB1,TMIE,GPSM2,PLP1,PMP22,EPB41L4B,POLG,POU3F4,PTN,TMEM145,STRC,ENOX1,RDX,FIGN,RFX3,GSTCD,RPL38,RXRA,SALL1,SCN8A,ELMOD1,KIF27,FBXO11,CCDC92,SLC1A3,SLC12A2,SNAP25,ANKFN1,WDTC1,SOX2,ZHX3,TSPYL2,LRRC4,ROBO3,AGTPBP1,ZEB1,SIRT1,AP4E1,THRA,WBP2,TUB,KLC2,ZNF24,ZNF142,FTSJ1,SLC30A4,PCDH15,UBE3B,VANGL2,MSRB3,NHSL1,AP3B2,SLC4A10" Mouse Phenotype MP:0009964 abnormal cerebellum lobule morphology 1.69E-03 1.00E+00 4.72E-02 4.51E-01 39 114 "ABR,SEMA4G,NUMB,CDK5R1,FUBP1,CDK5R2,DCLK1,DSCAM,DNM1L,EDIL3,EN2,ZIC4,GABRB3,DNER,GBX2,GLI2,CIT,L1CAM,MYCN,NEUROD1,NFIA,NRCAM,PLXNB1,POU3F2,RELN,LAMA1,PTCH1,PTK2,PEX2,KHDRBS2,FIGN,FBXW7,ZNF423,NPAS3,TRIO,VLDLR,ZIC1,LRP8,PDSS2" Mouse Phenotype MP:0011086 "postnatal lethality, incomplete penetrance" 1.71E-03 1.00E+00 4.73E-02 4.52E-01 209 798 "ACADM,DSCAML1,SLITRK1,ADCYAP1R1,CDC7,AGT,LTBP4,ALK,ANK1,APAF1,APC,APP,NUMB,RIPK1,HCN2,NRP2,FOXK1,CACNA1B,HAP1,CANX,RUNX1T1,CBS,CBFA2T2,CDC25B,DCLK1,CDO1,NUMBL,CACNA2D2,CFL2,NRXN1,NRXN2,QKI,CNR1,AKAP6,ZNF385A,CSF1,KIF26A,MAML1,BRINP1,DNAJC6,HP1BP3,PLPPR4,SNAP91,KIF19,DLG4,DMD,CDON,CPEB2,DMTF1,DPH1,DRD1,ATN1,DSCAM,DTNA,DYRK1A,E2F6,EDIL3,EDN3,HEYL,EFNA3,EGFR,MBNL2,EGR3,BSCL2,ERBB2,CACNG3,CACNG2,ZIC4,ZMYND10,SEC24B,ACTL6B,FGFR3,FOXG1,CAP2,DLL3,DOT1L,FYN,GAB1,GABBR1,GABRA1,GABRA2,GABRB3,GALC,GAP43,GBX2,GHR,PPARGC1A,GLDC,GLI2,GLRB,DCLK2,GNAL,GNAO1,GNAS,GPD2,GRIA2,GRIN1,RNF165,MFSD2A,PSIP1,HMGCR,HP,HSF2,IGF1,IL6ST,ITGAV,KCNA1,KCNQ2,KIT,L1CAM,LAMA2,LIMS1,SMAD9,MAN2A2,MDFI,MEST,KITLG,PPM1L,MITF,AFF1,MMP16,GIT1,MYCN,MYO5A,NEK1,NEUROD1,NF1,NFIA,NFE2L2,NPR2,NRCAM,NRDC,NTRK2,ODF2,PAX6,PCSK1,PDGFRA,PIK3R1,PKD1,FTO,RC3H2,MAGEL2,MBOAT7,MAPK8,MAPK9,PROX1,RELN,PTHLH,RET,FIGN,RGS4,RIC8B,KIRREL1,LGR4,RXRA,SBF1,CSRNP3,SCN8A,SMPD3,SCG5,ARX,SMTN,LIMS2,SLC6A9,SHANK2,SLC12A2,CPEB4,SMARCA4,SNAP25,SNRPN,SOX1,SOX2,SOX3,SOX10,SP2,SP4,ZNF423,NPAS3,TAB2,MESP1,SULF2,MGRN1,TCF4,ZEB1,TCF12,SYNE1,AKNA,FRYL,DICER1,SIRT1,LEFTY2,THRA,HEY1,HEY2,RBFOX2,TSC1,TSC2,UBE3A,FLRT2,USP1,VGF,LGI4,ZIC1,ZIC3,CELF4,ANKS1B,SMARCAD1,TMEM163,VANGL2" Mouse Phenotype MP:0001386 abnormal maternal nurturing 1.71E-03 1.00E+00 4.73E-02 4.52E-01 42 125 "APC,CACNA1A,NEURL1,RAB3C,WHRN,RIMS2,DLG4,SHANK1,EFNA3,CSPG5,FYN,GABRA1,GABRB3,GLRB,GNAL,GRIA2,GRIN1,GRM1,NKD1,MAP6,MBP,MEST,MITF,NRCAM,OXTR,ABCB1,TMIE,MAGEL2,RAB3A,FIGN,SHANK2,SLC12A2,NPAS3,TBX15,SIRT1,CHST8,THRA,NR2E1,LGI4,FMN2,PCDH15,TMEM163" Mouse Phenotype MP:0003202 abnormal neuron apoptosis 1.71E-03 1.00E+00 4.73E-02 4.52E-01 80 270 "NDRG2,UNC5A,KIDINS220,MRTFA,APAF1,CASK,ASCL1,NUMB,ASTN1,ATM,CAST,AIFM1,NUMBL,COPB2,PPT2,CNR1,MAGED1,CREM,CX3CR1,DAPK1,DCTN1,DNM1L,ELAVL4,EML1,EMX2,ENO2,APC2,PRMT5,MAD2L2,FOXG1,VTI1B,GFAP,GPR37,GRIA2,GRIN1,NR3C1,GRM2,CIT,GSTM5,HPCA,IGF1,INSM1,TUBB2B,LIG4,MAOB,MAPT,MBP,MEF2C,MOG,NOS1,NOVA1,NTRK2,OGG1,MBOAT7,MED1,MAPK9,MAPK10,OXR1,RET,RIC8B,FBXW7,CDK5RAP2,SNCA,SOX1,SOX10,SOX11,SPP1,TAL1,TLR4,TNFRSF1B,TP53BP2,RBFOX2,IL34,TRIO,TSC1,XRCC4,MAP3K12,PDSS2,EPM2A,ST8SIA2" Mouse Phenotype MP:0001732 postnatal growth retardation 1.75E-03 1.00E+00 4.81E-02 4.60E-01 252 980 "ACHE,AXIN2,SLC12A5,FZD9,AGT,CC2D2A,ALK,ANK1,APC,GPAM,AQP4,CASK,ARNTL,DACT3,NUMB,ATM,SLC4A4,ATP2B2,BCS1L,NRP2,BLM,SYNJ1,WASF1,DDR1,CACNB4,KALRN,HAP1,PTBP2,CAMK2B,HIP1R,RUNX1T1,AIFM1,LGI1,CDO1,NUMBL,CACNA2D2,CFL2,CHGA,CHRNB2,KMT2C,CLCN3,NIPBL,COL11A2,SMARCAL1,ZNF521,PREPL,CRHBP,SH2B1,CSF1,CSF1R,PNPLA8,CTH,HDAC9,KIF26A,RASSF2,MAML1,IP6K1,BRINP1,DBI,HP1BP3,MAGI2,SNAP91,SV2B,SV2A,KIF19,DMD,DNM2,DMTF1,DRD1,DSCAM,DTNA,ABCC9,E2F6,EDIL3,EDNRB,EEF1A2,EGFR,EN2,RCAN2,SLC43A2,ERBB2,ERCC2,APC2,CACNG2,RACK1,ZMYND10,FKTN,FDFT1,FGFR3,MAD2L2,SUCO,CAP2,FOXF2,STAMBP,GABRG2,GALC,ATP8A2,ACSS1,GCK,GGT5,GHR,GNAS,GNG3,FERMT2,GPD2,MCHR1,GRIA2,GRIN1,ATE1,KIF3A,RNF165,GUCY1B1,HPSE2,IGF1,NKD1,RBPJ,INPP5B,ITGA7,ITPKB,KCNA2,KCNC1,KCNJ10,KCNJ11,KIF5A,KIT,L1CAM,LAMA2,LIG4,LIMS1,MAPT,AQP11,KITLG,MMP16,ADAM22,MSRA,MYCN,MYO5A,MYO7A,MYO9A,NACA,NEUROD1,NEUROD2,NF1,NFIX,NKX2-2,NPR2,SLC11A2,NRCAM,NTRK2,DDR2,OCRL,PAH,PAX6,PCSK1,NLGN3,PIK3C2A,PKD1,SNX10,PLEC,FTO,EPN1,PMP22,POU3F2,MED1,HYDIN,RELN,PTCH1,PTHLH,PTH1R,PEX2,PEX5,RASGRF1,FEZF2,RET,FIGN,RFX3,RGS7,RGS10,RPL38,LGR4,SOX8,WLS,SATB1,ATXN1,SLC30A10,ITSN1,SH3GL2,ARX,FERMT1,SLC1A2,EPN2,SMTN,LIMS2,CCDC88A,SLC12A2,SLC14A1,SNCA,MBD5,SNRPN,SOX3,SOX10,SP2,SP4,NFASC,ITPRID2,SMOC1,SULF2,MLC1,PLCB1,TCF4,ZEB1,TCF12,USP22,SYNE1,FRYL,TF,DICER1,SIRT1,THRA,TJP1,TK2,NR2E1,HEY2,LRRC8A,TP53BP1,TRH,TRIO,TSN,TSC1,TSC2,TMEFF2,UBE3A,UGT8,LMF1,CLIP2,NSD2,PORCN,RICTOR,XRCC4,LGI4,ZIC1,ZIC3,SMARCAD1,SLC30A4,PCDH15,SLC17A7,SNX27,TMEM163,NLRP3,FXR1,IFT88,SLC4A10" Mouse Phenotype MP:0002623 abnormal vestibular hair cell morphology 1.79E-03 1.00E+00 4.91E-02 4.70E-01 19 45 "APAF1,ATP2B2,WHRN,USH1C,EYA1,CACNG2,FOXG1,SRRM4,HES5,KCNJ10,KIT,LAMA2,MYO6,MYO7A,NTRK2,ANKRD6,SOX2,PCDH15,VANGL2" Mouse Phenotype MP:0001431 abnormal eating behavior 1.82E-03 1.00E+00 4.97E-02 4.76E-01 156 578 "SLC25A25,UNC79,ALK,BIN1,OGT,APBA2,APP,LGR5,PRX,CASK,ASCL1,MARK4,ATM,BBS2,HCN2,WASF1,HAP1,BRSK2,RUNX1T1,CCKBR,NEURL1,LGI1,CDO1,CRLF1,CACNA2D2,CFL2,COPB2,FADS2,CNR1,CNTFR,CLOCK,CRHBP,SLC32A1,NCOR1,NCOR2,CSF1,SDC3,GPSM1,BRINP1,DCC,DNM1,DMTF1,DRD1,ATN1,GNE,DNM1L,BSCL2,EN2,OLIG2,RCAN2,GPHN,EZH1,FGFR3,PRKAG2,FOXG1,SEC23B,FOXF2,FLNC,CAMKK2,TBR1,FYN,GABRB3,GAD1,JPH4,SALL3,DISC1,ATP8A2,ACSS1,GATM,MSTN,GFRA2,GHR,PPARGC1A,GLUL,GNAL,GNAS,GPD2,PRLHR,MCHR1,GPR26,GRIN1,ATE1,GRM7,RNF165,PSIP1,HRH3,HNF4G,NEGR1,CPT1C,RBPJ,JAK1,KIF2A,MN1,CCDC80,RSPO2,MYO7A,NFE2L2,NOS1,NTRK2,P2RX7,PCSK1,PDPK1,PDYN,KCTD15,PLEC,FTO,PLIN1,PRRX1,MAGEL2,MBOAT7,SH3KBP1,IRX1,MAPK8,PROX1,PEX2,FEZF2,ROBO1,ROBO2,MRAP2,RMI1,SAFB,SALL1,SCN2A,SCP2,SCG5,SH3GL2,SH3GL3,SLC6A1,SLC6A9,CPEB4,SNAP25,SNRPN,ZNF423,ITPRID2,SYT1,TCF7L2,ZEB1,SYNE1,CRTC1,SIK3,SIRT1,THRA,ENHO,TLR4,TNFRSF1B,NR2C2,TRIO,TUB,UCHL1,VIPR2,ZIC1,SLC17A7,SLC17A6,PDSS2,EPM2A,JPH3" Domain IPR011993 PH_dom-like InterPro 1.56E-16 1.27E-12 1.27E-12 1.22E-11 149 427 "ABR,FAM43B,PLEKHG5,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,APBA2,APBB1,APBB2,EPB41L5,DGKD,ALS2,SPTBN4,CADPS,NUMB,MTMR9,KIF1A,DOCK11,ARHGEF7,BTK,MTMR3,MTMR2,KALRN,ARHGEF25,MTMR7,ARHGEF1,LRBA,ARHGEF2,NUMBL,PLEKHB1,ARHGAP22,NGEF,HOMER3,ARHGEF6,CDC42BPB,SH2B1,ARHGEF10,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,NOS1AP,ARHGAP24,FRMPD4,PLEKHM1,ELMO1,TIAM2,RABGAP1L,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,EPB41,EPB41L1,EPB41L2,EPS8,PTK2B,AGAP2,AGAP3,RGPD5,EVL,PSD2,NBEA,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,FRMD5,FRMD3,JAK1,JAK2,ARHGAP12,SHC3,MYO7A,OPHN1,SNTG1,PDPK1,ANLN,PLCB2,PLCD1,PLCL1,EPB41L4B,RANBP3L,PSD,MTMR10,PTK2,PTPN13,PID1,PLEKHB2,IQSEC3,RASGRF1,RASGRF2,VEPH1,RDX,RGS3,RGS12,ARHGEF10L,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FRMPD1,FERMT1,ASAP3,DOCK10,SHC4,CNKSR2,PREX2,PPP4R3A,ARHGEF40,ELMO2,DOK5,ARHGAP26,KIF1B,IQSEC2,MCF2L2,EPB41L3,MPRIP,PHLDB1,FGD4,ARHGEF9,PLCB1,MCF2L,DOCK9,PSD3,ARHGEF12,TNS2,ARHGAP9,TIAM1,TNS1,WBP2,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,ANKS1B,FRMD6,SPATA13" Domain 2.30.29.30 - Gene3D 1.81E-15 1.47E-11 3.83E-12 3.67E-11 137 391 "ABR,FAM43B,PLEKHG5,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,APBA2,APBB1,APBB2,EPB41L5,DGKD,ALS2,SPTBN4,CADPS,NUMB,MTMR9,KIF1A,DOCK11,ARHGEF7,BTK,MTMR3,MTMR2,KALRN,ARHGEF25,MTMR7,ARHGEF1,ARHGEF2,NUMBL,PLEKHB1,ARHGAP22,NGEF,HOMER3,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,NOS1AP,ARHGAP24,PLEKHM1,ELMO1,TIAM2,RABGAP1L,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,EPB41,EPB41L1,EPB41L2,EPS8,AGAP2,AGAP3,EVL,PSD2,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,FRMD5,FRMD3,ARHGAP12,SHC3,MYO7A,OPHN1,SNTG1,PDPK1,ANLN,PLCD1,PLCL1,EPB41L4B,RANBP3L,PSD,MTMR10,PTPN13,PID1,PLEKHB2,IQSEC3,RASGRF1,RASGRF2,VEPH1,RDX,RGS3,RGS12,ARHGEF10L,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,SHC4,CNKSR2,PREX2,PPP4R3A,ARHGEF40,ELMO2,DOK5,ARHGAP26,KIF1B,IQSEC2,MCF2L2,EPB41L3,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGEF12,TNS2,ARHGAP9,TIAM1,TNS1,WBP2,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,ANKS1B,FRMD6,SPATA13" Domain PF07679 I-set Pfam 1.88E-15 1.53E-11 3.83E-12 3.67E-11 82 190 "DSCAML1,UNC5A,LRFN2,ADGRF5,LRFN1,LRRC4C,IGDCC4,CADM3,MYOM1,KALRN,MYOM2,IGFN1,JAM2,IGLON5,CNTN1,NRG2,IGDCC3,LRIG1,BOC,DCC,MFAP3L,NTM,CDON,DSCAM,SPEG,FGFR1,FGFR3,FLT1,NPTN,CHL1,SIGLEC8,IGSF5,KIRREL3,ADGRA3,IL1RAPL1,LINGO1,VSIG4,IGFBPL1,NEGR1,L1CAM,LRRC4B,LSAMP,MAG,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,CNTN3,PRTG,PDGFRA,SDK2,LRRN3,MDGA2,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,IGSF9B,PALLD,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,ICAM5,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain IPR013098 Ig_I-set InterPro 1.88E-15 1.53E-11 3.83E-12 3.67E-11 82 190 "DSCAML1,UNC5A,LRFN2,ADGRF5,LRFN1,LRRC4C,IGDCC4,CADM3,MYOM1,KALRN,MYOM2,IGFN1,JAM2,IGLON5,CNTN1,NRG2,IGDCC3,LRIG1,BOC,DCC,MFAP3L,NTM,CDON,DSCAM,SPEG,FGFR1,FGFR3,FLT1,NPTN,CHL1,SIGLEC8,IGSF5,KIRREL3,ADGRA3,IL1RAPL1,LINGO1,VSIG4,IGFBPL1,NEGR1,L1CAM,LRRC4B,LSAMP,MAG,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,CNTN3,PRTG,PDGFRA,SDK2,LRRN3,MDGA2,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,IGSF9B,PALLD,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,ICAM5,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain SM00060 FN3 SMART 1.38E-13 1.12E-09 1.73E-10 1.66E-09 77 185 "ELFN2,DSCAML1,LRFN2,LRFN1,IGDCC4,ASTN1,MYOM1,KALRN,MYOM2,IGFN1,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,CSF3R,BOC,PHYHIP,DCC,KIAA0319,CDON,DSCAM,FSD1L,EBI3,EPHA5,EPHB1,SPEG,FLNC,PHYHIPL,CHL1,GHR,PTPRT,IL6R,IL6ST,IL11RA,L1CAM,LIFR,MID1,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,ROBO2,EPHA10,TRIM46,FNDC3A,TRIM67,IGSF9B,ANKFN1,NFASC,ASTN2,ROBO3,CNTN2,OBSL1,TEK,TIE1,RIMBP2,TNR,FNDC5,FLRT2,FLRT1,TRIM9" Domain SM00408 IGc2 SMART 1.49E-13 1.21E-09 1.73E-10 1.66E-09 91 235 "DSCAML1,LRFN2,ADGRF5,ALCAM,LRFN1,LRRC4C,IGDCC4,CADM3,MYOM1,KALRN,MYOM2,IGFN1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,CSF1R,LRIG1,BOC,DCC,MFAP3L,NTM,CDON,DSCAM,SPEG,FCGR1A,FCGR1B,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,SIGLEC8,MALT1,KIRREL3,LILRA1,LILRA2,IL1RAPL1,LINGO1,VSIG4,IGFBPL1,NEGR1,IGSF1,IL6R,KIT,L1CAM,LRRC4B,LSAMP,MAG,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,IGSF11,OPCML,CNTN3,PRTG,PDGFRA,SDK2,LRRN3,MDGA2,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,IGSF9B,PALLD,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain IPR003598 Ig_sub2 InterPro 1.49E-13 1.21E-09 1.73E-10 1.66E-09 91 235 "DSCAML1,LRFN2,ADGRF5,ALCAM,LRFN1,LRRC4C,IGDCC4,CADM3,MYOM1,KALRN,MYOM2,IGFN1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,CSF1R,LRIG1,BOC,DCC,MFAP3L,NTM,CDON,DSCAM,SPEG,FCGR1A,FCGR1B,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,SIGLEC8,MALT1,KIRREL3,LILRA1,LILRA2,IL1RAPL1,LINGO1,VSIG4,IGFBPL1,NEGR1,IGSF1,IL6R,KIT,L1CAM,LRRC4B,LSAMP,MAG,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,IGSF11,OPCML,CNTN3,PRTG,PDGFRA,SDK2,LRRN3,MDGA2,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,IGSF9B,PALLD,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SIGLEC10,ADAMTSL3" Domain PF00041 fn3 Pfam 6.75E-13 5.51E-09 6.89E-10 6.60E-09 69 162 "DSCAML1,LRFN2,LRFN1,IGDCC4,MYOM1,KALRN,MYOM2,IGFN1,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF3R,BOC,PHYHIP,DCC,CDON,DSCAM,FSD1L,EBI3,EPHA5,EPHB1,SPEG,PHYHIPL,CHL1,GHR,PTPRT,IL6R,IL6ST,IL11RA,L1CAM,LIFR,MID1,MYBPC1,NCAM1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,ROBO2,EPHA10,TRIM46,FNDC3A,TRIM67,IGSF9B,ANKFN1,NFASC,ROBO3,CNTN2,OBSL1,TEK,TIE1,RIMBP2,TNR,FNDC5,FLRT2,FLRT1,TRIM9" Domain IPR003961 FN3_dom InterPro 1.04E-12 8.47E-09 9.41E-10 9.02E-09 82 209 "ELFN2,DSCAML1,LRFN2,LRFN1,IGDCC4,ASTN1,MYOM1,KALRN,MYOM2,IGFN1,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,CSF3R,BOC,PHYHIP,DCC,KIAA0319,CDON,DSCAM,FSD1L,EBI3,EPHA5,EPHB1,SPEG,F3,FLNC,PHYHIPL,CHL1,GHR,PTPRT,IL6R,IL6ST,IL11RA,L1CAM,LIFR,MID1,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,MDGA2,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,ROBO2,EPHA10,LRFN5,TRIM46,FNDC3A,TRIM67,ATF7IP,IGSF9B,ANKFN1,NFASC,FNDC9,ASTN2,ROBO3,CNTN2,OBSL1,TEK,TIE1,RIMBP2,TNR,FNDC5,FLRT2,FLRT1,TRIM9" Domain PS50853 FN3 PROSITE 1.31E-12 1.07E-08 1.07E-09 1.03E-08 79 199 "ELFN2,DSCAML1,LRFN2,LRFN1,IGDCC4,ASTN1,MYOM1,KALRN,MYOM2,IGFN1,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF2RA,CSF3R,BOC,PHYHIP,DCC,CDON,DSCAM,FSD1L,EBI3,EPHA5,EPHB1,SPEG,PHYHIPL,CHL1,GHR,PTPRT,IL6R,IL6ST,IL11RA,L1CAM,LIFR,MID1,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,MDGA2,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,ROBO2,EPHA10,LRFN5,TRIM46,FNDC3A,TRIM67,ATF7IP,IGSF9B,ANKFN1,NFASC,FNDC9,ASTN2,ROBO3,CNTN2,OBSL1,TEK,TIE1,RIMBP2,TNR,FNDC5,FLRT2,FLRT1,TRIM9" Domain IPR013164 Cadherin_N InterPro 4.10E-12 3.35E-08 2.79E-09 2.67E-08 37 65 "PCDH19,PCDH10,PCDHGB4,PCDH17,PCDH11X,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Domain PF08266 Cadherin_2 Pfam 4.10E-12 3.35E-08 2.79E-09 2.67E-08 37 65 "PCDH19,PCDH10,PCDHGB4,PCDH17,PCDH11X,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Domain IPR002126 Cadherin InterPro 7.17E-12 5.85E-08 4.50E-09 4.31E-08 54 118 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,KIAA0319,CELSR3,CDHR1,FREM1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain IPR001849 PH_domain InterPro 1.02E-11 8.31E-08 5.94E-09 5.69E-08 99 281 "ABR,PLEKHG5,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,DGKD,ALS2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,ARHGAP24,PLEKHM1,ELMO1,TIAM2,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,EPS8,AGAP2,AGAP3,PSD2,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,ARHGAP12,OPHN1,SNTG1,PDPK1,ANLN,PLCD1,PLCL1,PSD,PLEKHB2,IQSEC3,RASGRF1,RASGRF2,VEPH1,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,TEX2,ARHGAP26,KIF1B,IQSEC2,MCF2L2,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGEF12,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,SPATA13" Domain PF00028 Cadherin Pfam 1.35E-11 1.10E-07 7.31E-09 7.01E-08 52 113 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain PS50003 PH_DOMAIN PROSITE 2.00E-11 1.63E-07 9.22E-09 8.83E-08 98 280 "ABR,PLEKHG5,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,DGKD,ALS2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,ARHGAP24,PLEKHM1,ELMO1,TIAM2,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,EPS8,AGAP2,AGAP3,PSD2,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,ARHGAP12,OPHN1,SNTG1,PDPK1,ANLN,PLCD1,PLCL1,PSD,PLEKHB2,IQSEC3,RASGRF1,RASGRF2,VEPH1,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,ARHGAP26,KIF1B,IQSEC2,MCF2L2,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGEF12,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,SPATA13" Domain 2.60.40.60 - Gene3D 2.03E-11 1.66E-07 9.22E-09 8.83E-08 52 114 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain PS50268 CADHERIN_2 PROSITE 2.03E-11 1.66E-07 9.22E-09 8.83E-08 52 114 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain SM00112 CA SMART 3.06E-11 2.49E-07 1.31E-08 1.26E-07 52 115 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain SM00233 PH SMART 3.89E-11 3.17E-07 1.59E-08 1.52E-07 97 279 "ABR,PLEKHG5,PLEKHH1,OSBPL1A,OSBPL6,OSBPL8,ARHGAP20,CDC42BPA,FGD2,DGKD,ALS2,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,ARHGAP24,PLEKHM1,ELMO1,TIAM2,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,AGAP2,AGAP3,PSD2,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,ARHGAP12,OPHN1,SNTG1,ANLN,PLCD1,PLCL1,PSD,PLEKHB2,IQSEC3,RASGRF1,RASGRF2,VEPH1,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,CNKSR2,PREX2,ARHGEF40,ELMO2,DOK5,TEX2,ARHGAP26,KIF1B,IQSEC2,MCF2L2,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGEF12,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,SPATA13" Domain IPR015919 Cadherin-like InterPro 4.56E-11 3.72E-07 1.77E-08 1.70E-07 52 116 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain PS00232 CADHERIN_1 PROSITE 5.14E-11 4.19E-07 1.90E-08 1.82E-07 51 113 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,CLSTN1,CLSTN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain IPR020894 Cadherin_CS InterPro 1.45E-10 1.18E-06 5.14E-08 4.93E-07 49 109 "PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CELSR3,CDHR1,PCDH17,PCDH11X,CDH20,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,DCHS2,FAT4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,PCDH20,PCDH15" Domain PF00595 PDZ Pfam 2.39E-10 1.95E-06 8.11E-08 7.77E-07 58 141 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,SNX27,GOPC" Domain PS50106 PDZ PROSITE 6.10E-10 4.98E-06 1.99E-07 1.91E-06 60 151 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,GORASP1,SNX27,GOPC" Domain IPR001478 PDZ InterPro 8.29E-10 6.76E-06 2.60E-07 2.49E-06 60 152 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,GORASP1,SNX27,GOPC" Domain 2.30.42.10 - Gene3D 1.34E-09 1.10E-05 4.06E-07 3.89E-06 59 150 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,GORASP1,SNX27,GOPC" Domain PF00169 PH Pfam 1.91E-09 1.56E-05 5.22E-07 5.00E-06 80 230 "ABR,PLEKHH1,OSBPL6,OSBPL8,CDC42BPA,FGD2,DGKD,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,KALRN,ARHGEF2,PLEKHB1,ARHGAP22,NGEF,ARHGEF6,CDC42BPB,SH2B1,OSBPL3,IPCEF1,PLCH2,APPL1,ARHGEF4,ARHGAP24,TIAM2,DNM1,DNM2,RASA4,PLEKHA1,PLEKHO1,AGAP2,AGAP3,PSD2,GAB1,FERMT2,ADAP1,GRB10,PLCD4,CIT,ARHGAP12,OPHN1,ANLN,PLCD1,PSD,PLEKHB2,RASGRF1,RASGRF2,VEPH1,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,CNKSR2,PREX2,DOK5,ARHGAP26,KIF1B,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGAP9,TIAM1,DOK6,TRIO,OSBP2,PLEKHH2,VAV1,VAV2,SPATA13" Domain SM00409 IG SMART 1.92E-09 1.57E-05 5.22E-07 5.00E-06 127 421 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,CADM3,MYOM1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,LRIG1,VCAN,NCAN,BOC,SIRPA,DCC,MFAP3L,NTM,CDON,DSCAM,SEMA3D,IGSF6,SPEG,SIRPB1,FCGR1A,FCGR1B,FCGR3A,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,ILDR2,SIGLEC8,IGSF5,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,IGSF1,IL6R,IL11RA,KIT,L1CAM,LRRC4B,LSAMP,MAG,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,SDK2,PILRA,LRRN3,VSTM2L,MDGA2,NCR3LG1,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,SCN2B,SCN4B,BCAN,IGSF9B,PALLD,SCN3B,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,TIE1,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SEMA3B,SIGLEC10,ADAMTSL3" Domain IPR003599 Ig_sub InterPro 1.92E-09 1.57E-05 5.22E-07 5.00E-06 127 421 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,CADM3,MYOM1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,LRIG1,VCAN,NCAN,BOC,SIRPA,DCC,MFAP3L,NTM,CDON,DSCAM,SEMA3D,IGSF6,SPEG,SIRPB1,FCGR1A,FCGR1B,FCGR3A,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,ILDR2,SIGLEC8,IGSF5,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,IGSF1,IL6R,IL11RA,KIT,L1CAM,LRRC4B,LSAMP,MAG,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,SDK2,PILRA,LRRN3,VSTM2L,MDGA2,NCR3LG1,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,SCN2B,SCN4B,BCAN,IGSF9B,PALLD,SCN3B,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,TIE1,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SEMA3B,SIGLEC10,ADAMTSL3" Domain SM00228 PDZ SMART 2.18E-09 1.78E-05 5.73E-07 5.49E-06 58 148 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,SNX27,GOPC" Domain PF16492 Cadherin_C_2 Pfam 3.52E-09 2.87E-05 8.69E-07 8.33E-06 25 42 "PCDH10,PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7" Domain IPR032455 Cadherin_C InterPro 3.52E-09 2.87E-05 8.69E-07 8.33E-06 25 42 "PCDH10,PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7" Domain IPR001452 SH3_domain InterPro 8.49E-09 6.93E-05 2.04E-06 1.95E-05 76 221 "CASKIN1,AMPH,BIN1,GAS7,CASK,ZNF582,DST,ARHGEF7,BTK,CACNB2,CACNB4,KALRN,ARHGAP33,NGEF,TJP2,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SRGAP3,DLG2,DLG3,DLG4,SHANK1,DOCK2,ABI1,SH3GLB1,ABI2,SORBS3,TNK2,EPS8,EFS,SH3YL1,PRAM1,BAIAP2,FGR,SORBS1,MPP6,FYB1,FYN,PACSIN2,ARHGAP12,MATK,MIA2,MPP2,DBNL,MYO7A,NCF2,PIK3R1,PACSIN1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SLA,SHANK2,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,TJP1,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,VAV2,SH3GLB2,SPATA13" Domain PS50002 SH3 PROSITE 1.99E-08 1.62E-04 4.63E-06 4.44E-05 74 217 "CASKIN1,AMPH,BIN1,GAS7,CASK,DST,ARHGEF7,BTK,CACNB2,CACNB4,KALRN,ARHGAP33,NGEF,TJP2,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SRGAP3,DLG2,DLG3,DLG4,SHANK1,DOCK2,ABI1,SH3GLB1,ABI2,SORBS3,TNK2,EPS8,EFS,SH3YL1,PRAM1,BAIAP2,FGR,SORBS1,MPP6,FYB1,FYN,PACSIN2,ARHGAP12,MATK,MPP2,DBNL,MYO7A,NCF2,PIK3R1,PACSIN1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SLA,SHANK2,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,TJP1,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,VAV2,SH3GLB2,SPATA13" Domain IPR031904 Cadherin_CBD InterPro 3.17E-08 2.59E-04 7.00E-06 6.70E-05 22 37 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Domain PF15974 Cadherin_tail Pfam 3.17E-08 2.59E-04 7.00E-06 6.70E-05 22 37 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Domain 2.60.40.10 - Gene3D 4.39E-08 3.58E-04 9.42E-06 9.03E-05 177 663 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,ASTN1,CADM3,MYOM1,AZGP1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,CRLF1,JAM2,IGLON5,CNTFR,CNTN1,ABI3BP,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,CSF2RA,CSF3R,LRIG1,VCAN,NCAN,PLXNA4,BOC,PHYHIP,SIRPA,DCC,MFAP3L,NTM,CDON,DSCAM,EBF1,SEMA3D,FSD1L,EBI3,PLXNC1,EPHA5,EPHB1,IGSF6,SPEG,SIRPB1,F3,FCGR1A,FCGR1B,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FLNC,FLT1,NPTN,PHYHIPL,CHL1,ILDR2,SIGLEC8,IGSF5,GHR,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,TMEM25,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,RBPJ,IGSF1,IL6R,IL6ST,IL11RA,KIT,L1CAM,LRRC4B,LIFR,LSAMP,MAG,MID1,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,NOMO2,PLXNB1,PLXNB3,SDK2,PILRA,FSD1,LRRN3,VSTM2L,MDGA2,NCR3LG1,PTPRB,PTPRD,PTPRG,PTPRO,PTPRZ1,ROBO1,KIRREL1,ROBO2,EPHA10,LRFN5,SCN2B,SCN4B,TRIM46,FNDC3A,BCAN,TRIM67,ATF7IP,IGSF9B,ANKFN1,PALLD,SCN3B,MYCBP2,UNC5B,NFASC,LRRC4,ASTN2,ROBO3,CAMTA1,UNC5D,CNTN2,TRIM2,OBSL1,TEK,TIE1,ICAM5,RIMBP2,TNR,LILRA4,LRRC24,TRIO,FNDC5,HEPACAM,CADM1,FLRT2,FLRT1,TRIM9,FSTL5,CADM2,SEMA3B,SIGLEC10,EPM2A,ADAMTSL3" Domain SM00326 SH3 SMART 4.67E-08 3.81E-04 9.76E-06 9.36E-05 73 217 "CASKIN1,AMPH,BIN1,GAS7,CASK,ARHGEF7,BTK,CACNB2,CACNB4,KALRN,ARHGAP33,NGEF,TJP2,ARHGEF6,ARHGEF4,DOCK4,ARHGAP32,RUSC2,SRGAP3,DLG2,DLG3,DLG4,SHANK1,DOCK2,ABI1,SH3GLB1,ABI2,SORBS3,TNK2,EPS8,EFS,SH3YL1,PRAM1,BAIAP2,FGR,SORBS1,MPP6,FYB1,FYN,PACSIN2,ARHGAP12,MATK,MPP2,DBNL,MYO7A,NCF2,PIK3R1,PACSIN1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SLA,SHANK2,FNBP1,ARHGAP26,SPTAN1,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,ARHGAP9,TJP1,RIMBP2,TP53BP2,TRIO,RUSC1,VAV1,VAV2,SH3GLB2,SPATA13" Domain IPR011009 Kinase-like_dom InterPro 1.46E-07 1.19E-03 2.98E-05 2.86E-04 148 543 "CLK4,CDC7,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,ATM,RIPK1,KSR1,BMPR1B,DST,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMD,DNM1,DMPK,RPS6KL1,DNM2,PDCD6IP,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,TTBK1,DCLK2,DIPK1C,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,KNDC1,JAK1,JAK2,KIT,MARK1,MARK3,MATK,STK32C,NRBP2,NEK1,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,CAMKV,PIK3C2A,PIK3CD,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,PTK2,PXK,STK32A,PTPN13,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,CHD9,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TIE1,CDK20,TRIO,SGK3,WNK1,MAP3K12,PRDM2,WNK3,WNK2,PAK5,CAMK1G" Domain IPR013783 Ig-like_fold InterPro 1.67E-07 1.36E-03 3.32E-05 3.18E-04 184 707 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,ASTN1,CADM3,MYOM1,AZGP1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,CRLF1,JAM2,IGLON5,CNTFR,CNTN1,ABI3BP,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,CSF2RA,CSF3R,LRIG1,VCAN,NCAN,PLXNA4,BOC,PHYHIP,SIRPA,DCC,MFAP3L,KIAA0319,NTM,CDON,DSCAM,EBF1,SEMA3D,FSD1L,EBI3,PLXNC1,EPHA5,EPHB1,IGSF6,SPEG,SIRPB1,F3,FCGR1A,FCGR1B,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FLNC,FLT1,NPTN,PHYHIPL,CHL1,ILDR2,SIGLEC8,IGSF5,GHR,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,TMEM25,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,RBPJ,IGSF1,IL6R,IL6ST,IL11RA,KIT,L1CAM,LRRC4B,LIFR,LSAMP,MAG,MID1,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,NOMO2,PLXNB1,PLXNB3,SDK2,PILRA,FSD1,LRRN3,VSTM2L,PRKAB2,MDGA2,NCR3LG1,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,KIRREL1,ROBO2,EPHA10,LRFN5,SCN2B,SCN4B,TRIM46,FNDC3A,BCAN,TRIM67,SHANK2,ATF7IP,IGSF9B,ANKFN1,PALLD,SCN3B,MYCBP2,UNC5B,NFASC,CAMTA2,LRRC4,FNDC9,ASTN2,SEMA4A,ROBO3,CAMTA1,UNC5D,CNTN2,TRIM2,OBSL1,TEK,TIE1,ICAM5,RIMBP2,TNR,LILRA4,LRRC24,TRIO,FNDC5,HEPACAM,CADM1,FLRT2,FLRT1,TRIM9,FSTL5,CADM2,SEMA3B,SIGLEC10,EPM2A,ADAMTSL3" Domain IPR000719 Prot_kinase_dom InterPro 2.34E-07 1.91E-03 4.54E-05 4.35E-04 135 489 "CLK4,CDC7,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK1,JAK2,KIT,MARK1,MARK3,MATK,STK32C,NRBP2,NEK1,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,CAMKV,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,PTK2,PXK,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TIE1,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain PS50011 PROTEIN_KINASE_DOM PROSITE 3.86E-07 3.14E-03 7.31E-05 7.01E-04 135 493 "CLK4,CDC7,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,PAN3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK1,JAK2,KIT,MARK1,MARK3,MATK,STK32C,NRBP2,NEK1,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,CAMKV,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,PTK2,PXK,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TIE1,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain PS00741 DH_1 PROSITE 4.31E-07 3.52E-03 7.99E-05 7.66E-04 29 63 "ABR,PLEKHG5,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain IPR011511 SH3_2 InterPro 4.90E-07 4.00E-03 8.60E-05 8.24E-04 36 87 "CASKIN1,AMPH,BIN1,CASK,ARHGEF7,ARHGAP33,TJP2,ARHGEF6,DOCK4,RUSC2,DLG2,SHANK1,DOCK2,SORBS3,BAIAP2,SORBS1,MPP6,FYB1,MIA2,MPP2,PIK3R1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SHANK2,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,TJP1,RIMBP2,VAV2,SH3GLB2" Domain PF07653 SH3_2 Pfam 4.90E-07 4.00E-03 8.60E-05 8.24E-04 36 87 "CASKIN1,AMPH,BIN1,CASK,ARHGEF7,ARHGAP33,TJP2,ARHGEF6,DOCK4,RUSC2,DLG2,SHANK1,DOCK2,SORBS3,BAIAP2,SORBS1,MPP6,FYB1,MIA2,MPP2,PIK3R1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SHANK2,SAMSN1,STAC2,ARHGEF9,MCF2L,DNMBP,TJP1,RIMBP2,VAV2,SH3GLB2" Domain PF00621 RhoGEF Pfam 5.06E-07 4.13E-03 8.60E-05 8.24E-04 31 70 "ABR,PLEKHG5,FGD2,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain PS50010 DH_2 PROSITE 5.06E-07 4.13E-03 8.60E-05 8.24E-04 31 70 "ABR,PLEKHG5,FGD2,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain PF00168 C2 Pfam 5.55E-07 4.53E-03 9.24E-05 8.85E-04 48 131 "CPNE2,ABR,ESYT2,HECW2,CC2D2A,SYT13,DOC2A,CPNE5,CADPS,BAIAP3,SYT6,CPNE6,C2CD2,PLCH2,RIMS4,RIMS2,RIMS3,SYT15,RASA4,SYT3,SYT17,PCLO,PLCD4,C2CD4C,SYTL4,SYT9,CPNE9,PIK3C2A,PLCB2,PLCD1,PLCL1,PRKCB,PRKCG,SYTL2,RGS3,RASA3,ITSN1,RPH3A,RIMS1,HECW1,SYT11,PLCB1,SYT1,SYT4,SYT5,WWC1,RPGRIP1L,CPNE4" Domain IPR028082 Peripla_BP_I InterPro 6.59E-07 5.37E-03 1.08E-04 1.03E-03 21 39 "GRIN3A,GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NPR2" Domain 1.20.900.10 - Gene3D 7.41E-07 6.04E-03 1.16E-04 1.11E-03 31 71 "ABR,PLEKHG5,FGD2,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain IPR000219 DH-domain InterPro 7.41E-07 6.04E-03 1.16E-04 1.11E-03 31 71 "ABR,PLEKHG5,FGD2,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain PF00060 Lig_chan Pfam 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain PF10613 Lig_chan-Glu_bd Pfam 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain IPR001508 Iono_rcpt_met InterPro 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain SM00918 Lig_chan-Glu_bd SMART 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain IPR019594 Glu/Gly-bd InterPro 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain SM00079 PBPe SMART 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain IPR001320 Iontro_rcpt InterPro 8.89E-07 7.25E-03 1.23E-04 1.18E-03 13 18 "GRIN3A,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D" Domain PF01094 ANF_receptor Pfam 1.12E-06 9.15E-03 1.50E-04 1.44E-03 20 37 "GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NPR2" Domain IPR001828 ANF_lig-bd_rcpt InterPro 1.12E-06 9.15E-03 1.50E-04 1.44E-03 20 37 "GABBR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NPR2" Domain PS00107 PROTEIN_KINASE_ATP PROSITE 1.40E-06 1.14E-02 1.85E-04 1.77E-03 125 459 "CLK4,CDC7,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,BMPR1B,BTK,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SRPK3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,JAK1,JAK2,KIT,MARK1,MARK3,MATK,STK32C,NEK1,NTRK2,NTRK3,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,PTK2,STK32A,RET,RNASEL,NEK11,EPHA10,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TIE1,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain IPR013151 Immunoglobulin InterPro 1.51E-06 1.23E-02 1.93E-04 1.85E-03 62 190 "DSCAML1,ADGRF5,ALCAM,MYOM1,JAM2,IGLON5,CNTFR,IGDCC3,CSF1R,BOC,NTM,CDON,DSCAM,FCGR1A,FCGR1B,FCGR3A,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,SIGLEC8,MALT1,ADGRA3,LILRB4,LILRA1,LILRA2,IL1RAPL1,IGSF21,VSIG4,NEGR1,IGSF1,IL6R,IL11RA,KIT,MAG,CD200,MDGA1,NCAM1,NCAM2,NRCAM,NTRK3,OPCML,CNTN3,PDGFRA,SDK2,VSTM2L,MDGA2,PTPRD,NFASC,LRRC4,UNC5D,CNTN2,OBSL1,TIE1,ICAM5,LILRA4,FSTL5,SEMA3B,SIGLEC10,ADAMTSL3" Domain PF00047 ig Pfam 1.51E-06 1.23E-02 1.93E-04 1.85E-03 62 190 "DSCAML1,ADGRF5,ALCAM,MYOM1,JAM2,IGLON5,CNTFR,IGDCC3,CSF1R,BOC,NTM,CDON,DSCAM,FCGR1A,FCGR1B,FCGR3A,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,SIGLEC8,MALT1,ADGRA3,LILRB4,LILRA1,LILRA2,IL1RAPL1,IGSF21,VSIG4,NEGR1,IGSF1,IL6R,IL11RA,KIT,MAG,CD200,MDGA1,NCAM1,NCAM2,NRCAM,NTRK3,OPCML,CNTN3,PDGFRA,SDK2,VSTM2L,MDGA2,PTPRD,NFASC,LRRC4,UNC5D,CNTN2,OBSL1,TIE1,ICAM5,LILRA4,FSTL5,SEMA3B,SIGLEC10,ADAMTSL3" Domain IPR000008 C2_dom InterPro 2.25E-06 1.84E-02 2.78E-04 2.67E-03 55 164 "CPNE2,ABR,ESYT2,HECW2,OSBPL6,CC2D2A,SYT13,DOC2A,CPNE5,CADPS,BAIAP3,SYT6,CPNE6,C2CD2,PLCH2,RIMS4,RIMS2,RIMS3,DNAJC6,C2CD2L,SYT15,RASA4,SYT3,SYT17,PCLO,PLCD4,C2CD4C,SYTL4,SYT9,CPNE9,PIK3C2A,PIK3CD,PLCB2,PLCD1,PLCL1,PRKCB,PRKCG,PKN2,SYTL2,RGS3,RASA3,ITSN1,RPH3A,RIMS1,HECW1,SYT11,PLCB1,SYT1,SYT4,SYT5,WWC1,RPGRIP1L,TNS2,TNS1,CPNE4" Domain PF00018 SH3_1 Pfam 2.25E-06 1.84E-02 2.78E-04 2.67E-03 55 164 "AMPH,BIN1,GAS7,DST,ARHGEF7,BTK,CACNB2,CACNB4,ARHGAP33,NGEF,ARHGEF6,ARHGEF4,ARHGAP32,SRGAP3,DLG2,DLG3,DLG4,ABI1,SH3GLB1,ABI2,SORBS3,TNK2,EPS8,EFS,SH3YL1,FGR,SORBS1,FYN,PACSIN2,ARHGAP12,MATK,DBNL,NCF2,PIK3R1,PACSIN1,SH3KBP1,SH3TC2,ITSN1,SH3GL2,SH3GL3,SLA,FNBP1,ARHGAP26,SPTAN1,STAC2,ARHGEF9,DNMBP,ARHGAP9,TP53BP2,TRIO,RUSC1,VAV1,VAV2,SH3GLB2,SPATA13" Domain IPR017441 Protein_kinase_ATP_BS InterPro 2.36E-06 1.93E-02 2.88E-04 2.76E-03 106 379 "CLK4,CDC7,TAOK1,ALK,CDC42BPA,MAP4K3,CDK10,CDK13,STK33,MARK4,BMPR1B,BTK,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,DCLK1,TAOK2,MAP4K4,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,DYRK1A,SGK2,HIPK3,EGFR,TNK2,SRPK3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,PTK2B,TAOK3,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,MYLK2,NIM1K,JAK1,JAK2,KIT,MARK1,MARK3,MATK,STK32C,NEK1,NTRK2,NTRK3,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,SNRK,PTK2,STK32A,RET,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,TIE1,CDK20,SGK3,PAK5,CAMK1G" Domain SM00239 C2 SMART 2.45E-06 2.00E-02 2.94E-04 2.82E-03 48 137 "CPNE2,ABR,ESYT2,HECW2,CC2D2A,SYT13,DOC2A,CPNE5,CADPS,BAIAP3,SYT6,CPNE6,C2CD2,PLCH2,RIMS4,RIMS2,RIMS3,SYT15,RASA4,SYT3,SYT17,PCLO,PLCD4,C2CD4C,SYTL4,SYT9,CPNE9,PIK3C2A,PLCB2,PLCD1,PLCL1,PRKCB,PRKCG,PKN2,SYTL2,RGS3,RASA3,ITSN1,RPH3A,RIMS1,HECW1,SYT11,PLCB1,SYT1,SYT4,SYT5,RPGRIP1L,CPNE4" Domain PS50835 IG_LIKE PROSITE 2.86E-06 2.33E-02 3.38E-04 3.24E-03 131 492 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,CADM3,MYOM1,AZGP1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,CRLF1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,LRIG1,VCAN,NCAN,BOC,SIRPA,DCC,MFAP3L,NTM,CDON,DSCAM,SEMA3D,IGSF6,SPEG,SIRPB1,FCGR1A,FCGR1B,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,ILDR2,SIGLEC8,IGSF5,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,TMEM25,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,IGSF1,IL6R,IL11RA,KIT,L1CAM,LRRC4B,LSAMP,MAG,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,SDK2,PILRA,LRRN3,VSTM2L,MDGA2,NCR3LG1,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,SCN2B,SCN4B,BCAN,IGSF9B,PALLD,SCN3B,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,TEK,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SEMA3B,SIGLEC10,ADAMTSL3" Domain SM00325 RhoGEF SMART 2.99E-06 2.44E-02 3.49E-04 3.34E-03 29 68 "ABR,PLEKHG5,FGD2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Domain PS50004 C2 PROSITE 3.18E-06 2.59E-02 3.65E-04 3.50E-03 49 142 "CPNE2,ABR,ESYT2,HECW2,CC2D2A,SYT13,DOC2A,CPNE5,CADPS,BAIAP3,SYT6,CPNE6,C2CD2,PLCH2,RIMS4,RIMS2,RIMS3,SYT15,RASA4,SYT3,SYT17,PCLO,PLCD4,C2CD4C,SYTL4,SYT9,CPNE9,PIK3C2A,PLCB2,PLCD1,PLCL1,PRKCB,PRKCG,PKN2,SYTL2,RGS3,RASA3,ITSN1,RPH3A,RIMS1,HECW1,SYT11,PLCB1,SYT1,SYT4,SYT5,WWC1,RPGRIP1L,CPNE4" Domain IPR001331 GDS_CDC24_CS InterPro 3.33E-06 2.72E-02 3.77E-04 3.62E-03 20 39 "ABR,ALS2,ARHGEF7,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,ITSN1,PREX2,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2" Domain IPR007110 Ig-like_dom InterPro 3.98E-06 3.24E-02 4.44E-04 4.26E-03 133 504 "DSCAML1,UNC5A,LRFN2,ADGRF5,ALCAM,LRFN1,SEMA7A,LRRC4C,SEMA4G,IGDCC4,CADM3,MYOM1,AZGP1,KALRN,VSTM2A,CD86,MYOM2,IGFN1,CRLF1,JAM2,IGLON5,CNTFR,CNTN1,NRG2,IGDCC3,NECTIN3,HAPLN1,CSF1R,CSF3R,LRIG1,VCAN,NCAN,BOC,SIRPA,DCC,MFAP3L,NTM,CDON,DSCAM,SEMA3D,IGSF6,SPEG,SIRPB1,FCGR1A,FCGR1B,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FLT1,NPTN,CHL1,ILDR2,SIGLEC8,IGSF5,MALT1,KIRREL3,ADGRA3,LILRB4,LILRA1,LILRA2,BTN2A1,PTPRT,TMEM25,IL1RAPL1,LINGO1,IGSF21,VSIG4,HAPLN2,IGFBPL1,NEGR1,IGSF1,IL6R,IL11RA,KIT,L1CAM,LRRC4B,LSAMP,MAG,MOG,CD200,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,TREM2,CNTN3,PRTG,PDGFRA,SDK2,PILRA,LRRN3,VSTM2L,MDGA2,NCR3LG1,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,SCN2B,SCN4B,BCAN,IGSF9B,PALLD,SCN3B,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,TEK,TIE1,ICAM5,LILRA4,LRRC24,TRIO,HEPACAM,CADM1,FSTL5,CADM2,SEMA3B,SIGLEC10,ADAMTSL3" Domain IPR019748 FERM_central InterPro 4.41E-06 3.59E-02 4.79E-04 4.59E-03 23 49 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain IPR000299 FERM_domain InterPro 4.41E-06 3.59E-02 4.79E-04 4.59E-03 23 49 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain IPR014352 FERM/acyl-CoA-bd_prot_3-hlx InterPro 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,ACBD5,FRMPD4,DBI,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain IPR019749 Band_41_domain InterPro 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain PS00660 FERM_1 PROSITE 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain PS50057 FERM_3 PROSITE 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain SM00295 B41 SMART 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain PS00661 FERM_2 PROSITE 6.75E-06 5.50E-02 6.80E-04 6.51E-03 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain IPR000483 Cys-rich_flank_reg_C InterPro 1.12E-05 9.11E-02 1.10E-03 1.05E-02 34 90 "ELFN2,SLITRK1,LRFN2,LRFN1,LRRC4C,LGI1,SLIT2,LRIG1,SLITRK5,LRRC17,TLR7,ADGRA3,GP1BB,LINGO1,LRRC4B,LRIT2,NTRK2,NTRK3,PKD1,LRRN3,LGI2,LRFN5,SLITRK3,LRRC55,LGI3,SLIT1,LRRC4,TLR4,LRRC24,LRTM2,FLRT2,FLRT1,LGI4,ELFN1" Domain SM00082 LRRCT SMART 1.12E-05 9.11E-02 1.10E-03 1.05E-02 34 90 "ELFN2,SLITRK1,LRFN2,LRFN1,LRRC4C,LGI1,SLIT2,LRIG1,SLITRK5,LRRC17,TLR7,ADGRA3,GP1BB,LINGO1,LRRC4B,LRIT2,NTRK2,NTRK3,PKD1,LRRN3,LGI2,LRFN5,SLITRK3,LRRC55,LGI3,SLIT1,LRRC4,TLR4,LRRC24,LRTM2,FLRT2,FLRT1,LGI4,ELFN1" Domain 2.60.40.150 - Gene3D 1.17E-05 9.52E-02 1.13E-03 1.08E-02 49 148 "CPNE2,ABR,ESYT2,HECW2,CC2D2A,SYT13,DOC2A,CPNE5,BAIAP3,SYT6,CPNE6,C2CD2,PLCH2,RIMS4,RIMS2,RIMS3,C2CD2L,RASA4,SYT3,SYT17,PCLO,PLCD4,C2CD4C,SYTL4,SYT9,CPNE9,PIK3C2A,PIK3CD,PLCB2,PLCD1,PLCL1,PRKCB,PRKCG,PKN2,SYTL2,RGS3,RASA3,ITSN1,RPH3A,RIMS1,HECW1,SYT11,PLCB1,SYT1,SYT4,SYT5,WWC1,RPGRIP1L,CPNE4" Domain IPR009071 HMG_box_dom InterPro 1.18E-05 9.58E-02 1.13E-03 1.08E-02 27 65 "KMT2C,CHD5,TOX,TOX3,SOX21,MAEL,TOX2,HMGB1,MIA2,PROX1,PBRM1,SOX8,SOX6,SH3GL2,FAM81A,SMARCE1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,TCF7,TCF7L2,UBTF,NSD2" Domain 1.20.80.10 - Gene3D 1.72E-05 1.40E-01 1.63E-03 1.57E-02 22 49 "PLEKHH1,EPB41L5,KRIT1,ACBD5,FRMPD4,DBI,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain PF00373 FERM_M Pfam 1.95E-05 1.59E-01 1.83E-03 1.75E-02 21 46 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Domain IPR011011 Znf_FYVE_PHD InterPro 2.15E-05 1.75E-01 1.99E-03 1.91E-02 48 147 "DPF1,KDM5D,FGD2,PHF12,ZFYVE28,MTMR3,BSN,KMT2C,ZFYVE9,MYRIP,CHD5,PHF14,RIMS2,PYGO1,PHF19,ZFYVE16,PHF20L1,ING4,ANKFY1,BRPF3,ZMYND11,KDM2B,PCLO,DIDO1,RFFL,SYTL4,ZFYVE27,MOBP,ZFYVE21,ING3,SYTL2,DPF2,UBR7,RPH3A,RUFY2,RIMS1,KDM4B,KDM3A,KDM4C,FGD4,PHF24,NSD1,KAT6B,ZMYND8,NSD2,SPIRE1,KAT6A,DPF3" Domain IPR027359 Channel_four-helix_dom InterPro 2.71E-05 2.21E-01 2.46E-03 2.35E-02 24 57 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,HVCN1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,NALCN,SCN2A,SCN3A,SCN7A,SCN8A,TPCN2" Domain 1.20.120.350 - Gene3D 2.71E-05 2.21E-01 2.46E-03 2.35E-02 24 57 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,HVCN1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,NALCN,SCN2A,SCN3A,SCN7A,SCN8A,TPCN2" Domain SM00220 S_TKc SMART 2.87E-05 2.34E-01 2.57E-03 2.46E-02 97 359 "CLK4,CDC7,TAOK1,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,CSNK1G3,DAPK1,DAPK3,DMPK,DYRK1A,SGK2,HIPK3,IRAK4,SRPK3,SPEG,CDKL3,RPS6KC1,TAOK3,CAMKK2,BRSK1,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,MYLK2,NIM1K,MARK1,MARK3,STK32C,NEK1,KSR2,PAK3,CDK18,PDGFRA,PDPK1,CDK14,PHKG1,CAMKV,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,STK32A,RNASEL,NEK11,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,TEK,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain SM00109 C1 SMART 3.74E-05 3.05E-01 3.28E-03 3.14E-02 26 65 "CDC42BPA,DGKZ,DGKD,KSR1,DGKI,ARHGEF2,CHN1,CHN2,KMT2C,CDC42BPB,DGKB,DGKG,PLEKHM1,RASGRP1,RASGRP2,CIT,MYO9A,KSR2,PRKCB,PRKCG,PRKCZ,DEF8,STAC2,TNS2,VAV1,VAV2" Domain SM00033 CH SMART 3.74E-05 3.05E-01 3.28E-03 3.14E-02 26 65 "ACTN1,ACTN2,LRCH2,SPTBN4,DST,ARHGEF7,CNN3,ARHGEF6,MICAL2,DMD,FLNC,SPECC1,IQGAP2,TAGLN3,PLEC,SMTN,LIMCH1,SPTB,SYNE2,EHBP1,SYNE1,VAV1,VAV2,MICAL1,NAV3,NAV2" Domain IPR001565 Synaptotagmin InterPro 4.15E-05 3.38E-01 3.60E-03 3.45E-02 12 20 "DOC2A,SYT6,SYT3,SYT17,PCLO,SYTL4,SYT9,RPH3A,SYT11,SYT1,SYT4,SYT5" Domain PF00069 Pkinase Pfam 4.55E-05 3.71E-01 3.91E-03 3.75E-02 101 381 "CLK4,CDC7,TAOK1,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,BMPR1B,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,IRAK4,SRPK3,SPEG,CDKL3,RPS6KC1,TAOK3,STRADA,TESK2,CAMKK2,BRSK1,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,MARK1,MARK3,STK32C,NRBP2,NEK1,NPR2,KSR2,PAK3,CDK18,PDPK1,CDK14,PHKG1,CAMKV,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,PXK,STK32A,RNASEL,NEK11,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,CDK20,TRIO,SGK3,WNK1,WNK3,WNK2,PAK5,CAMK1G" Domain PS50021 CH PROSITE 4.70E-05 3.84E-01 3.95E-03 3.79E-02 28 73 "ACTN1,ACTN2,LRCH2,SPTBN4,DST,ARHGEF7,CNN3,ARHGEF6,MICAL2,DMD,CAMSAP1,FLNC,SPECC1,IQGAP2,TAGLN3,PLEC,SMTN,LIMCH1,SPTB,SYNE2,CAMSAP2,EHBP1,SYNE1,VAV1,VAV2,MICAL1,NAV3,NAV2" Domain PF00435 Spectrin Pfam 4.72E-05 3.85E-01 3.95E-03 3.79E-02 13 23 "ACTN1,ACTN2,SPTBN4,DST,KALRN,DMD,DRP2,SPTAN1,SPTB,SYNE2,MCF2L,SYNE1,TRIO" Domain SM00150 SPEC SMART 4.80E-05 3.91E-01 3.95E-03 3.79E-02 16 32 "ACTN1,ACTN2,SPTBN4,DST,KALRN,AKAP6,DMD,DRP2,PLEC,SPTAN1,SPTB,MCF2L2,SYNE2,MCF2L,SYNE1,TRIO" Domain IPR018159 Spectrin/alpha-actinin InterPro 4.80E-05 3.91E-01 3.95E-03 3.79E-02 16 32 "ACTN1,ACTN2,SPTBN4,DST,KALRN,AKAP6,DMD,DRP2,PLEC,SPTAN1,SPTB,MCF2L2,SYNE2,MCF2L,SYNE1,TRIO" Domain IPR002219 PE/DAG-bd InterPro 5.10E-05 4.16E-01 4.16E-03 3.98E-02 26 66 "CDC42BPA,DGKZ,DGKD,KSR1,DGKI,ARHGEF2,CHN1,CHN2,KMT2C,CDC42BPB,DGKB,DGKG,PLEKHM1,RASGRP1,RASGRP2,CIT,MYO9A,KSR2,PRKCB,PRKCG,PRKCZ,DEF8,STAC2,TNS2,VAV1,VAV2" Domain IPR011989 ARM-like InterPro 5.43E-05 4.43E-01 4.38E-03 4.20E-02 76 271 "ARID1A,AP2A1,AP2A2,AP1B1,USP35,GPRASP2,ARMC12,PKP4,APC,API5,PPP4R4,LRBA,PLAA,HECTD1,NIPBL,ARMC8,RTTN,TOGARAM2,CTNND1,CTNND2,PUM1,PPP6R2,GPRASP1,RIPOR2,ARMCX2,ELMO1,MED12,DOCK2,MRO,APC2,ARMCX1,NBEA,ATP6V1H,AP4B1,STAG2,CAB39,HMGB1,KPNA5,IPO5,CHIC1,MN1,NF1,TNPO2,PPP2R5C,PPP2R5E,RIPOR1,RAP1GDS1,ZYG11B,RIC8B,ARMC5,ARMH4,LRRK2,DOCK10,FHOD3,PPP4R3A,ELMO2,CAND2,CLASP2,MMS19,TAF6,AGTPBP1,CLASP1,PUM2,FRYL,AP4E1,BHLHB9,DAAM2,TSC2,HSPBP1,FAM155A,RICTOR,XPO1,CAB39L,DOCK8,RSPRY1,AP3B2" Domain PS00108 PROTEIN_KINASE_ST PROSITE 6.83E-05 5.57E-01 5.46E-03 5.23E-02 96 362 "CLK4,CDC7,TAOK1,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,IRAK4,SRPK3,SPEG,CDKL3,RPS6KC1,TAOK3,CAMKK2,BRSK1,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,MARK1,MARK3,STK32C,NEK1,KSR2,PAK3,CDK18,PDPK1,CDK14,PHKG1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,STK32A,NEK11,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,TTBK2,SIK3,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain 1.10.418.10 - Gene3D 7.60E-05 6.20E-01 6.01E-03 5.76E-02 27 71 "ACTN1,ACTN2,LRCH2,SPTBN4,DST,ARHGEF7,CNN3,ARHGEF6,MICAL2,DMD,FLNC,SPECC1,IQGAP2,TAGLN3,PLEC,SMTN,LIMCH1,SPTB,SYNE2,CAMSAP2,EHBP1,SYNE1,VAV1,VAV2,MICAL1,NAV3,NAV2" Domain PF00618 RasGEF_N Pfam 8.05E-05 6.57E-01 6.32E-03 6.05E-02 12 21 "RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR001715 CH-domain InterPro 8.25E-05 6.73E-01 6.34E-03 6.07E-02 28 75 "ACTN1,ACTN2,LRCH2,SPTBN4,DST,ARHGEF7,CNN3,ARHGEF6,MICAL2,DMD,CAMSAP1,FLNC,SPECC1,IQGAP2,TAGLN3,PLEC,SMTN,LIMCH1,SPTB,SYNE2,CAMSAP2,EHBP1,SYNE1,VAV1,VAV2,MICAL1,NAV3,NAV2" Domain PS50081 ZF_DAG_PE_2 PROSITE 8.31E-05 6.78E-01 6.34E-03 6.07E-02 25 64 "CDC42BPA,DGKZ,DGKD,KSR1,DGKI,ARHGEF2,CHN1,CHN2,CDC42BPB,DGKB,DGKG,PLEKHM1,RASGRP1,RASGRP2,CIT,MYO9A,KSR2,PRKCB,PRKCG,PRKCZ,DEF8,STAC2,TNS2,VAV1,VAV2" Domain PS00479 ZF_DAG_PE_1 PROSITE 8.31E-05 6.78E-01 6.34E-03 6.07E-02 25 64 "CDC42BPA,DGKZ,DGKD,KSR1,DGKI,ARHGEF2,CHN1,CHN2,CDC42BPB,DGKB,DGKG,PLEKHM1,RASGRP1,RASGRP2,CIT,MYO9A,KSR2,PRKCB,PRKCG,PRKCZ,DEF8,STAC2,TNS2,VAV1,VAV2" Domain PF00520 Ion_trans Pfam 9.07E-05 7.40E-01 6.79E-03 6.50E-02 38 114 "KCNH8,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CNGA3,HVCN1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNMA1,KCNQ2,KCNQ3,HCN1,NALCN,RYR1,RYR3,SCN2A,SCN3A,SCN7A,SCN8A,TPCN2,TRPC1,TRPC3,TRPM2" Domain IPR005821 Ion_trans_dom InterPro 9.07E-05 7.40E-01 6.79E-03 6.50E-02 38 114 "KCNH8,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CNGA3,HVCN1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNMA1,KCNQ2,KCNQ3,HCN1,NALCN,RYR1,RYR3,SCN2A,SCN3A,SCN7A,SCN8A,TPCN2,TRPC1,TRPC3,TRPM2" Domain PF02210 Laminin_G_2 Pfam 9.58E-05 7.81E-01 7.10E-03 6.81E-02 18 40 "CNTNAP1,SLIT2,NRXN3,NRXN1,NRXN2,COL11A2,CNTNAP2,CELSR3,LAMA2,NELL1,NELL2,FAT3,LAMA1,FAT4,CNTNAP3,SLIT1,CRB1,CRB2" Domain IPR008271 Ser/Thr_kinase_AS InterPro 1.07E-04 8.74E-01 7.88E-03 7.55E-02 94 357 "CLK4,CDC7,TAOK1,CDC42BPA,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,RIPK1,KSR1,BMPR1B,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CDK11B,DCLK1,TAOK2,MAP4K4,CDC42BPB,CSNK1E,CSNK1G3,DAPK1,DAPK3,DMPK,RPS6KL1,DYRK1A,SGK2,HIPK3,SRPK3,SPEG,CDKL3,RPS6KC1,TAOK3,CAMKK2,BRSK1,NEK6,TTBK1,DCLK2,GRK4,CIT,MAP4K5,IRAK3,MYLK2,NIM1K,MARK1,MARK3,STK32C,NEK1,KSR2,PAK3,CDK18,PDPK1,CDK14,PHKG1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,SNRK,STK32A,NEK11,RPS6KA2,STK32B,LRRK2,HUNK,MAPK12,SGK1,MAST1,TNIK,CDK19,SRPK2,NEK4,SIK3,CDK20,TRIO,SGK3,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Domain IPR016024 ARM-type_fold InterPro 1.21E-04 9.90E-01 8.84E-03 8.48E-02 90 340 "RALGAPA1,ARID1A,FMNL2,AP2A1,AP2A2,AP1B1,USP35,UNC79,GPRASP2,ARMC12,PKP4,APC,API5,PPP4R4,ATM,EIF4G3,DOCK11,FMNL3,LRBA,PLAA,CLTC,HECTD1,NIPBL,ARMC8,RTTN,TOGARAM2,MROH8,CTNND1,CTNND2,PUM1,PPP6R2,GPRASP1,RIPOR2,INTS1,CTIF,ARMCX2,ELMO1,DOCK2,MRO,EIF4G1,EIF4G2,EIF5,APC2,ARMCX1,NBEA,ATP6V1H,AP4B1,STAG2,CAB39,KPNA5,IPO5,NF1,PIK3C2A,PIK3CD,TNPO2,PPP2R5C,PPP2R5E,RIPOR1,RAP1GDS1,VEPH1,ZYG11B,RIC8B,ARMC5,LRRK2,RYR3,FHOD3,PPP4R3A,ELMO2,CAND2,CLASP2,NCDN,MMS19,TAF6,AGTPBP1,CLASP1,DOCK9,PUM2,FRYL,AP4E1,BHLHB9,DAAM2,TSC2,HSPBP1,CLHC1,RICTOR,XPO1,CAB39L,DOCK8,RSPRY1,AP3B2" Domain IPR008936 Rho_GTPase_activation_prot InterPro 1.25E-04 1.00E+00 9.03E-03 8.65E-02 31 88 "ABR,ARHGAP20,ARHGAP5,ARHGAP33,CHN1,CHN2,ARHGAP22,PLXNA4,ARHGAP32,GAPVD1,ARHGAP24,SRGAP3,FAM13A,PLXNC1,RASA4,DLC1,IQGAP2,ARHGAP19,ARHGAP36,INPP5B,ARHGAP12,MYO9A,NF1,OCRL,OPHN1,PIK3R1,PLXNB1,PLXNB3,RASA3,ARHGAP26,ARHGAP9" Domain 1.10.30.10 - Gene3D 1.45E-04 1.00E+00 1.04E-02 9.92E-02 22 55 "CHD5,TOX,TOX3,SOX21,MAEL,TOX2,HMGB1,PBRM1,SOX8,SOX6,SMARCE1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,TCF7,TCF7L2,UBTF,NSD2" Domain PS50212 RASGEF_NTER PROSITE 1.48E-04 1.00E+00 1.04E-02 9.92E-02 12 22 "RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR000651 Ras-like_Gua-exchang_fac_N InterPro 1.48E-04 1.00E+00 1.04E-02 9.92E-02 12 22 "RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain SM00516 SEC14 SMART 1.48E-04 1.00E+00 1.04E-02 9.92E-02 13 25 "KALRN,SEC14L5,CLVS1,PRUNE2,ATCAY,CLVS2,NF1,RLBP1,SEC14L1,MCF2L2,MCF2L,TRIO,TTPA" Domain PF00307 CH Pfam 1.61E-04 1.00E+00 1.11E-02 1.07E-01 26 70 "ACTN1,ACTN2,LRCH2,SPTBN4,DST,ARHGEF7,CNN3,ARHGEF6,MICAL2,DMD,FLNC,SPECC1,IQGAP2,TAGLN3,PLEC,SMTN,LIMCH1,SPTB,SYNE2,EHBP1,SYNE1,VAV1,VAV2,MICAL1,NAV3,NAV2" Domain SM00181 EGF SMART 1.77E-04 1.00E+00 1.20E-02 1.15E-01 66 236 "ZNF578,LTBP4,CNTNAP1,TMEFF1,BRINP2,ASTN1,ADAM23,ADAM15,SLIT2,NRXN3,NRXN1,NRXN2,NRG2,TENM4,ATRNL1,VCAN,NCAN,CNTNAP2,EDIL3,CELSR3,TENM1,EFEMP1,CSPG5,DLL3,NRG3,MEGF11,MEGF10,TMEM8B,DNER,ADAM28,NTNG2,WIF1,BRINP3,LAMA2,CLEC18A,MATN2,MATN3,ADAM11,LRP1B,ADAM22,NELL1,NELL2,VWA2,PCSK5,FAT3,RELN,LAMA1,FAT4,CNTNAP3,PEAR1,SELL,NTNG1,BCAN,SLIT1,VWCE,TEK,CRB1,HHIP,THBS4,TIE1,TLL2,TNR,TMEFF2,VLDLR,CRB2,LRP8" Domain SM00218 ZU5 SMART 1.77E-04 1.00E+00 1.20E-02 1.15E-01 7 9 "UNC5A,ANK1,ANK2,ANK3,UNC5B,UNC5D,TJP1" Domain IPR003585 Neurexin-like InterPro 1.91E-04 1.00E+00 1.28E-02 1.22E-01 9 14 "CNTNAP1,CADM3,NRXN3,NRXN1,NRXN2,CNTNAP2,SDC3,CADM1,CADM2" Domain SM00294 4.1m SMART 1.91E-04 1.00E+00 1.28E-02 1.22E-01 9 14 "CNTNAP1,CADM3,NRXN3,NRXN1,NRXN2,CNTNAP2,SDC3,CADM1,CADM2" Domain PF01437 PSI Pfam 2.08E-04 1.00E+00 1.37E-02 1.31E-01 15 32 "SEMA6A,SEMA7A,SEMA4G,ATRNL1,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain IPR002165 Plexin_repeat InterPro 2.08E-04 1.00E+00 1.37E-02 1.31E-01 15 32 "SEMA6A,SEMA7A,SEMA4G,ATRNL1,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain IPR002017 Spectrin_repeat InterPro 2.30E-04 1.00E+00 1.50E-02 1.44E-01 14 29 "ACTN1,ACTN2,SPTBN4,DST,KALRN,DMD,DRP2,PLEC,SPTAN1,SPTB,SYNE2,MCF2L,SYNE1,TRIO" Domain PF00505 HMG_box Pfam 2.38E-04 1.00E+00 1.53E-02 1.47E-01 21 53 "KMT2C,TOX,TOX3,SOX21,TOX2,HMGB1,PBRM1,SOX8,SOX6,SMARCE1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,TCF7,TCF7L2,UBTF,NSD2" Domain PF01462 LRRNT Pfam 2.38E-04 1.00E+00 1.53E-02 1.47E-01 21 53 "LRRC4C,LGR5,SLIT2,LRIG1,LRRC3B,SLITRK5,GP1BB,LRRTM3,LRRC4B,NTRK2,NTRK3,OMG,PKD1,LRRN3,LGR4,LRRC55,SLIT1,LRRC4,LRTM2,FLRT2,FLRT1" Domain SM00072 GuKc SMART 2.47E-04 1.00E+00 1.54E-02 1.48E-01 13 26 "CASK,CACNB2,CACNB4,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain PF00625 Guanylate_kin Pfam 2.47E-04 1.00E+00 1.54E-02 1.48E-01 13 26 "CASK,CACNB2,CACNB4,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain IPR008145 GK/Ca_channel_bsu InterPro 2.47E-04 1.00E+00 1.54E-02 1.48E-01 13 26 "CASK,CACNB2,CACNB4,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain IPR008144 Guanylate_kin-like_dom InterPro 2.47E-04 1.00E+00 1.54E-02 1.48E-01 13 26 "CASK,CACNB2,CACNB4,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain SM00229 RasGEFN SMART 2.55E-04 1.00E+00 1.58E-02 1.51E-01 11 20 "RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain PF00130 C1_1 Pfam 2.67E-04 1.00E+00 1.64E-02 1.57E-01 22 57 "CDC42BPA,DGKZ,DGKD,KSR1,DGKI,ARHGEF2,CHN1,CHN2,CDC42BPB,DGKB,DGKG,RASGRP1,RASGRP2,CIT,KSR2,PRKCB,PRKCG,PRKCZ,DEF8,STAC2,VAV1,VAV2" Domain IPR020635 Tyr_kinase_cat_dom InterPro 3.08E-04 1.00E+00 1.86E-02 1.79E-01 30 88 "ALK,BTK,DDR1,CSF1R,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1" Domain SM00219 TyrKc SMART 3.08E-04 1.00E+00 1.86E-02 1.79E-01 30 88 "ALK,BTK,DDR1,CSF1R,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1" Domain PS50026 EGF_3 PROSITE 3.14E-04 1.00E+00 1.88E-02 1.80E-01 65 236 "LTBP4,CNTNAP1,TMEFF1,ASTN1,ADAM23,ADAM15,SLIT2,NRXN3,NRXN1,NRXN2,NRG2,TENM4,ATRNL1,VCAN,NCAN,CNTNAP2,EDIL3,CELSR3,TENM1,EFEMP1,CSPG5,DLL3,NRG3,MEGF11,MEGF10,TMEM8B,DNER,ADAM28,NTNG2,WIF1,MSANTD3-TMEFF1,CLEC18A,MATN2,MATN3,ADAM11,LRP1B,ADAM22,NELL1,NELL2,VWA2,FAT3,MASP1,RELN,FAT4,CRTAC1,CNTNAP3,PEAR1,SELL,NTNG1,BCAN,SLIT1,SSPO,ASTN2,VWCE,TEK,CRB1,HHIP,THBS4,TIE1,TLL2,TNR,TMEFF2,VLDLR,CRB2,LRP8" Domain PF09379 FERM_N Pfam 3.17E-04 1.00E+00 1.88E-02 1.80E-01 15 33 "EPB41L5,EPB41,EPB41L1,EPB41L2,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,FRMD6" Domain IPR018979 FERM_N InterPro 3.17E-04 1.00E+00 1.88E-02 1.80E-01 15 33 "EPB41L5,EPB41,EPB41L1,EPB41L2,FERMT2,FRMD5,FRMD3,MYO7A,EPB41L4B,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,FRMD6" Domain PS50118 HMG_BOX_2 PROSITE 3.23E-04 1.00E+00 1.88E-02 1.81E-01 21 54 "TOX,TOX3,SOX21,MAEL,TOX2,HMGB1,PBRM1,SOX8,SOX6,SMARCE1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,TCF7,TCF7L2,UBTF,NSD2" Domain SM00398 HMG SMART 3.23E-04 1.00E+00 1.88E-02 1.81E-01 21 54 "KMT2C,TOX,TOX3,SOX21,TOX2,HMGB1,PBRM1,SOX8,SOX6,SMARCE1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,TCF7,TCF7L2,UBTF,NSD2" Domain SM00462 PTB SMART 3.46E-04 1.00E+00 2.00E-02 1.92E-01 17 40 "FAM43B,APBA2,APBB1,APBB2,NUMB,NUMBL,APPL1,NOS1AP,RABGAP1L,EPS8,SHC3,PID1,RGS12,SHC4,TNS2,TNS1,ANKS1B" Domain PS00109 PROTEIN_KINASE_TYR PROSITE 3.88E-04 1.00E+00 2.21E-02 2.12E-01 32 97 "ALK,BTK,DDR1,AATK,CSF1R,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1" Domain IPR008266 Tyr_kinase_AS InterPro 3.88E-04 1.00E+00 2.21E-02 2.12E-01 32 97 "ALK,BTK,DDR1,AATK,CSF1R,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1" Domain PS50191 CRAL_TRIO PROSITE 3.97E-04 1.00E+00 2.25E-02 2.15E-01 13 27 "KALRN,SEC14L5,CLVS1,PRUNE2,ATCAY,CLVS2,NF1,RLBP1,SEC14L1,MCF2L2,MCF2L,TRIO,TTPA" Domain SM00282 LamG SMART 4.12E-04 1.00E+00 2.32E-02 2.22E-01 18 44 "CNTNAP1,SLIT2,NRXN3,NRXN1,NRXN2,COL11A2,CNTNAP2,CELSR3,LAMA2,NELL1,NELL2,FAT3,LAMA1,FAT4,CNTNAP3,SLIT1,CRB1,CRB2" Domain SM00831 Cation_ATPase_N SMART 4.41E-04 1.00E+00 2.41E-02 2.31E-01 10 18 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP13A4,ATP2C1,ATP13A2" Domain SM00593 RUN SMART 4.41E-04 1.00E+00 2.41E-02 2.31E-01 10 18 "RUBCN,PLEKHM1,RUSC2,SGSM2,SNX29,RUNDC3A,SGSM1,RUFY2,RUNDC3B,RUSC1" Domain SM00231 FA58C SMART 4.47E-04 1.00E+00 2.41E-02 2.31E-01 11 21 "CNTNAP1,NRP2,DDR1,CNTNAP2,EDIL3,F5,F8,DDR2,CNTNAP3,SSPO,DCBLD1" Domain PS01285 FA58C_1 PROSITE 4.47E-04 1.00E+00 2.41E-02 2.31E-01 11 21 "CNTNAP1,NRP2,DDR1,CNTNAP2,EDIL3,F5,F8,DDR2,CNTNAP3,SSPO,DCBLD1" Domain PS50022 FA58C_3 PROSITE 4.47E-04 1.00E+00 2.41E-02 2.31E-01 11 21 "CNTNAP1,NRP2,DDR1,CNTNAP2,EDIL3,F5,F8,DDR2,CNTNAP3,SSPO,DCBLD1" Domain PS01286 FA58C_2 PROSITE 4.47E-04 1.00E+00 2.41E-02 2.31E-01 11 21 "CNTNAP1,NRP2,DDR1,CNTNAP2,EDIL3,F5,F8,DDR2,CNTNAP3,SSPO,DCBLD1" Domain IPR000372 LRRNT InterPro 4.76E-04 1.00E+00 2.53E-02 2.42E-01 32 98 "SLITRK1,LRFN2,LRRC4C,LGR5,LGI1,SLIT2,LRIG1,LRRC3B,SLITRK5,TLR7,GP1BB,LINGO1,LRRTM3,LRRTM1,LRRC4B,LRIT2,NTRK2,NTRK3,OMG,PKD1,LRRN3,LGR4,LRFN5,LRRTM4,SLITRK3,LRRC55,SLIT1,LRRC4,LRRC24,LRTM2,FLRT2,FLRT1" Domain SM00013 LRRNT SMART 4.76E-04 1.00E+00 2.53E-02 2.42E-01 32 98 "SLITRK1,LRFN2,LRRC4C,LGR5,LGI1,SLIT2,LRIG1,LRRC3B,SLITRK5,TLR7,GP1BB,LINGO1,LRRTM3,LRRTM1,LRRC4B,LRIT2,NTRK2,NTRK3,OMG,PKD1,LRRN3,LGR4,LRFN5,LRRTM4,SLITRK3,LRRC55,SLIT1,LRRC4,LRRC24,LRTM2,FLRT2,FLRT1" Domain IPR000048 IQ_motif_EF-hand-BS InterPro 4.77E-04 1.00E+00 2.53E-02 2.42E-01 30 90 "MYH7B,IQCG,IQGAP2,GAP43,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,NRGN,CEP97,IQSEC3,RASGRF1,RASGRF2,MYH14,SCN2A,SCN3A,SCN7A,SCN8A,MYO18A,MYO16,ENKUR,IQSEC2,CAMTA2,CAMTA1,IQCE,XKR7,UBE3B" Domain IPR006020 PTB/PI_dom InterPro 4.91E-04 1.00E+00 2.59E-02 2.48E-01 17 41 "FAM43B,APBA2,APBB1,APBB2,NUMB,NUMBL,APPL1,NOS1AP,RABGAP1L,EPS8,SHC3,PID1,RGS12,SHC4,TNS2,TNS1,ANKS1B" Domain PS51145 ZU5 PROSITE 4.96E-04 1.00E+00 2.60E-02 2.49E-01 7 10 "UNC5A,ANK1,ANK2,ANK3,UNC5B,UNC5D,TJP1" Domain SM00630 Sema SMART 5.44E-04 1.00E+00 2.77E-02 2.66E-01 14 31 "SEMA6A,SEMA7A,SEMA4G,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain PS51004 SEMA PROSITE 5.44E-04 1.00E+00 2.77E-02 2.66E-01 14 31 "SEMA6A,SEMA7A,SEMA4G,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain PF01403 Sema Pfam 5.44E-04 1.00E+00 2.77E-02 2.66E-01 14 31 "SEMA6A,SEMA7A,SEMA4G,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain IPR001627 Semap_dom InterPro 5.44E-04 1.00E+00 2.77E-02 2.66E-01 14 31 "SEMA6A,SEMA7A,SEMA4G,PLXNA4,SEMA3D,PLXNC1,SEMA6C,SEMA4D,SEMA5B,PLXNB1,PLXNB3,SEMA6D,SEMA4A,SEMA3B" Domain 2.60.120.200 - Gene3D 5.86E-04 1.00E+00 2.97E-02 2.84E-01 31 95 "CNTNAP1,CANX,LRBA,CLGN,SLIT2,NRXN3,NRXN1,NRXN2,COL9A1,COL11A2,CNTNAP2,CELSR3,ADGRV1,NBEA,LAMA2,NELL1,NELL2,NPTX1,NPTX2,FAT3,LAMA1,PTX3,FAT4,CNTNAP3,CLSTN1,SLIT1,CLSTN2,CRB1,THBS4,CRB2,LMAN2L" Domain PF07974 EGF_2 Pfam 6.15E-04 1.00E+00 3.07E-02 2.94E-01 22 60 "ADAM23,ADAM15,TENM4,ATRNL1,EDIL3,TENM1,DLL3,MEGF11,MEGF10,DNER,NTNG2,WIF1,ADAM11,LRP1B,ADAM22,NELL1,NELL2,RELN,TEK,HHIP,TIE1,TNR" Domain IPR013111 EGF_extracell InterPro 6.15E-04 1.00E+00 3.07E-02 2.94E-01 22 60 "ADAM23,ADAM15,TENM4,ATRNL1,EDIL3,TENM1,DLL3,MEGF11,MEGF10,DNER,NTNG2,WIF1,ADAM11,LRP1B,ADAM22,NELL1,NELL2,RELN,TEK,HHIP,TIE1,TNR" Domain IPR001251 CRAL-TRIO_dom InterPro 6.17E-04 1.00E+00 3.07E-02 2.94E-01 13 28 "KALRN,SEC14L5,CLVS1,PRUNE2,ATCAY,CLVS2,NF1,RLBP1,SEC14L1,MCF2L2,MCF2L,TRIO,TTPA" Domain SM01195 FA SMART 6.79E-04 1.00E+00 3.32E-02 3.18E-01 8 13 "EPB41L5,EPB41,EPB41L1,EPB41L2,FRMD5,FRMD3,EPB41L4B,EPB41L3" Domain IPR014847 FERM-adjacent InterPro 6.79E-04 1.00E+00 3.32E-02 3.18E-01 8 13 "EPB41L5,EPB41,EPB41L1,EPB41L2,FRMD5,FRMD3,EPB41L4B,EPB41L3" Domain PF08736 FA Pfam 6.79E-04 1.00E+00 3.32E-02 3.18E-01 8 13 "EPB41L5,EPB41,EPB41L1,EPB41L2,FRMD5,FRMD3,EPB41L4B,EPB41L3" Domain PF07714 Pkinase_Tyr Pfam 7.04E-04 1.00E+00 3.42E-02 3.28E-01 39 129 "ALK,RIPK1,KSR1,BMPR1B,BTK,DDR1,AATK,CSF1R,EGFR,IRAK4,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NPR2,NTRK2,NTRK3,DDR2,KSR2,PDGFRA,PTK2,RET,EPHA10,TEK,TIE1,MAP3K12" Domain 1.10.196.10 - Gene3D 7.46E-04 1.00E+00 3.57E-02 3.42E-01 11 22 "AXIN2,RGS20,RGS11,RGS9,RGS6,RGS17,RGS3,RGS4,RGS7,RGS10,RGS12" Domain IPR024066 RGS_subdom1 InterPro 7.46E-04 1.00E+00 3.57E-02 3.42E-01 11 22 "AXIN2,RGS20,RGS11,RGS9,RGS6,RGS17,RGS3,RGS4,RGS7,RGS10,RGS12" Domain IPR003388 Reticulon InterPro 7.58E-04 1.00E+00 3.57E-02 3.42E-01 6 8 "RTN3,RETREG1,RETREG2,RTN1,PRR18,RTN4" Domain IPR000162 GPCR_3_mtglu_rcpt InterPro 7.58E-04 1.00E+00 3.57E-02 3.42E-01 6 8 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Domain IPR020590 Guanylate_kinase_CS InterPro 7.65E-04 1.00E+00 3.57E-02 3.42E-01 9 16 "CASK,MAGI1,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3" Domain PS01186 EGF_2 PROSITE 7.73E-04 1.00E+00 3.57E-02 3.42E-01 70 266 "LTBP4,CNTNAP1,TMEFF1,ASTN1,ADAM23,ADAM15,SLIT2,NRXN3,NRXN1,NRXN2,NRG2,TENM4,ATRNL1,VCAN,NCAN,CNTNAP2,EDIL3,CELSR3,TENM1,EPHA5,EPHB1,EFEMP1,CSPG5,DLL3,NRG3,MEGF11,MEGF10,TMEM8B,DNER,ADAM28,NTNG2,WIF1,LAMA2,MSANTD3-TMEFF1,CLEC18A,MATN2,MATN3,ADAM11,LRP1B,ADAM22,NELL1,NELL2,VWA2,FAT3,MASP1,RELN,LAMA1,FAT4,CRTAC1,EPHA10,CNTNAP3,PEAR1,SELL,NTNG1,BCAN,SLIT1,SSPO,ASTN2,VWCE,TEK,CRB1,HHIP,THBS4,TIE1,TLL2,TNR,TMEFF2,VLDLR,CRB2,LRP8" Domain IPR004012 Run_dom InterPro 7.79E-04 1.00E+00 3.57E-02 3.42E-01 10 19 "RUBCN,PLEKHM1,RUSC2,SGSM2,SNX29,RUNDC3A,SGSM1,RUFY2,RUNDC3B,RUSC1" Domain IPR004014 ATPase_P-typ_cation-transptr_N InterPro 7.79E-04 1.00E+00 3.57E-02 3.42E-01 10 19 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP13A4,ATP2C1,ATP13A2" Domain PF02759 RUN Pfam 7.79E-04 1.00E+00 3.57E-02 3.42E-01 10 19 "RUBCN,PLEKHM1,RUSC2,SGSM2,SNX29,RUNDC3A,SGSM1,RUFY2,RUNDC3B,RUSC1" Domain PS50826 RUN PROSITE 7.79E-04 1.00E+00 3.57E-02 3.42E-01 10 19 "RUBCN,PLEKHM1,RUSC2,SGSM2,SNX29,RUNDC3A,SGSM1,RUFY2,RUNDC3B,RUSC1" Domain 1.25.10.10 - Gene3D 8.75E-04 1.00E+00 3.99E-02 3.82E-01 60 222 "ARID1A,AP2A1,AP2A2,AP1B1,ARMC12,PKP4,APC,API5,PPP4R4,LRBA,HECTD1,NIPBL,ARMC8,RTTN,TOGARAM2,CTNND1,CTNND2,PUM1,GPRASP1,RIPOR2,ARMCX2,ELMO1,MED12,MRO,APC2,ARMCX1,ATP6V1H,AP4B1,CAB39,KPNA5,IPO5,CHIC1,NF1,TNPO2,PPP2R5C,PPP2R5E,RIPOR1,RAP1GDS1,ZYG11B,RIC8B,ARMC5,LRRK2,ELMO2,CAND2,CLASP2,MMS19,TAF6,AGTPBP1,CLASP1,PUM2,FRYL,AP4E1,BHLHB9,DAAM2,TSC2,HSPBP1,RICTOR,XPO1,CAB39L,AP3B2" Domain SM00015 IQ SMART 8.94E-04 1.00E+00 4.05E-02 3.88E-01 27 81 "MYH7B,IQCG,IQGAP2,GAP43,MYH3,MYH6,MYH7,MYO5A,MYO6,MYO7A,MYO9A,NRGN,CEP97,RASGRF1,RASGRF2,MYH14,SCN2A,SCN3A,SCN7A,SCN8A,MYO18A,MYO16,CAMTA2,CAMTA1,IQCE,XKR7,UBE3B" Domain PS50009 RASGEF_CAT PROSITE 9.32E-04 1.00E+00 4.20E-02 4.03E-01 13 29 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR001757 P_typ_ATPase InterPro 9.80E-04 1.00E+00 4.35E-02 4.16E-01 15 36 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP13A4,ATP2C1,ATP8A2,ATP8B4,ATP10B,ATP11A,ATP13A2" Domain IPR018303 ATPase_P-typ_P_site InterPro 9.80E-04 1.00E+00 4.35E-02 4.16E-01 15 36 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP13A4,ATP2C1,ATP8A2,ATP8B4,ATP10B,ATP11A,ATP13A2" Domain PS00154 ATPASE_E1_E2 PROSITE 9.80E-04 1.00E+00 4.35E-02 4.16E-01 15 36 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP13A4,ATP2C1,ATP8A2,ATP8B4,ATP10B,ATP11A,ATP13A2" Domain SM00324 RhoGAP SMART 1.03E-03 1.00E+00 4.51E-02 4.32E-01 22 62 "ABR,ARHGAP20,ARHGAP5,ARHGAP33,CHN1,CHN2,ARHGAP22,ARHGAP32,ARHGAP24,SRGAP3,FAM13A,DLC1,ARHGAP19,ARHGAP36,INPP5B,ARHGAP12,MYO9A,OCRL,OPHN1,PIK3R1,ARHGAP26,ARHGAP9" Domain PS00720 RASGEF PROSITE 1.07E-03 1.00E+00 4.51E-02 4.32E-01 12 26 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR001390 GABAAa_rcpt InterPro 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5" Domain IPR005492 EPTP InterPro 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "LGI1,ADGRV1,LGI2,LGI3,LGI4" Domain IPR002515 Znf_C2HC InterPro 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "L3MBTL4,ST18,KAT7,MYT1,MYT1L" Domain PF01530 zf-C2HC Pfam 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "L3MBTL4,ST18,KAT7,MYT1,MYT1L" Domain PF11878 DUF3398 Pfam 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "DOCK11,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR021816 DOCK_C/D_N InterPro 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "DOCK11,DOCK7,DOCK10,DOCK9,DOCK8" Domain PF03736 EPTP Pfam 1.07E-03 1.00E+00 4.51E-02 4.32E-01 5 6 "LGI1,ADGRV1,LGI2,LGI3,LGI4" Domain PS50178 ZF_FYVE PROSITE 1.14E-03 1.00E+00 4.61E-02 4.42E-01 16 40 "FGD2,ZFYVE28,MTMR3,ZFYVE9,MYRIP,RIMS2,ZFYVE16,ANKFY1,RFFL,SYTL4,ZFYVE27,ZFYVE21,RPH3A,RUFY2,RIMS1,FGD4" Domain PS51650 DHR_1 PROSITE 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain PS51651 DHR_2 PROSITE 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR027357 DHR-2 InterPro 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain PF02318 FYVE_2 Pfam 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "MYRIP,RIMS2,SYTL4,MOBP,SYTL2,RPH3A,RIMS1" Domain PF06920 DHR-2 Pfam 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR010703 DOCK_C InterPro 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR027007 DHR-1_domain InterPro 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR026791 DOCK InterPro 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain PF14429 DOCK-C2 Pfam 1.15E-03 1.00E+00 4.61E-02 4.42E-01 7 11 "DOCK11,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Domain IPR028325 VG_K_chnl InterPro 1.16E-03 1.00E+00 4.64E-02 4.44E-01 14 33 "KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNMA1,KCNQ2,KCNQ3" Domain SM00225 BTB SMART 1.19E-03 1.00E+00 4.64E-02 4.44E-01 50 180 "KLHL32,KLHL13,KCTD16,SPOP,ZBTB10,BACH1,RCBTB2,KCTD8,ZBTB24,KLHL3,RHOBTB1,KBTBD11,KLHL5,KCTD3,ANKFY1,KBTBD12,ZBTB49,ZBTB45,BACH2,BTBD17,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KLHL23,KCTD6,KCTD15,KCTD17,KLHL11,BTBD3,KBTBD4,BTBD7,ABTB1,ZBTB43,KLHL7,KLHL4,GZF1,NACC2,KCTD2,ZBTB14,ZBTB38,ZBTB16,GAN" Domain PS50052 GUANYLATE_KINASE_2 PROSITE 1.19E-03 1.00E+00 4.64E-02 4.44E-01 11 23 "CASK,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain PF00855 PWWP Pfam 1.19E-03 1.00E+00 4.64E-02 4.44E-01 11 23 "PWWP2A,BRPF3,ZMYND11,GLYR1,PSIP1,MUM1,ZCWPW1,MBD5,NSD1,ZMYND8,NSD2" Domain 3.40.525.10 - Gene3D 1.19E-03 1.00E+00 4.64E-02 4.44E-01 11 23 "KALRN,SEC14L5,CLVS1,PRUNE2,ATCAY,CLVS2,RLBP1,SEC14L1,MCF2L2,TRIO,TTPA" Domain PS00856 GUANYLATE_KINASE_1 PROSITE 1.19E-03 1.00E+00 4.64E-02 4.44E-01 11 23 "CASK,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Domain IPR000313 PWWP_dom InterPro 1.19E-03 1.00E+00 4.64E-02 4.44E-01 11 23 "PWWP2A,BRPF3,ZMYND11,GLYR1,PSIP1,MUM1,ZCWPW1,MBD5,NSD1,ZMYND8,NSD2" Domain IPR000210 BTB/POZ_dom InterPro 1.28E-03 1.00E+00 4.95E-02 4.75E-01 51 185 "KLHL32,KLHL13,KCTD16,SPOP,ZBTB10,BACH1,RCBTB2,KCTD8,ZBTB24,KLHL3,RHOBTB1,KBTBD11,KLHL5,KCTD3,ANKFY1,KBTBD12,ZBTB49,ZBTB45,BACH2,BTBD17,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KLHL23,KCTD6,KCTD15,KCTD17,KLHL11,ARMC5,BTBD3,KBTBD4,BTBD7,ABTB1,ZBTB43,KLHL7,KLHL4,GZF1,NACC2,KCTD2,ZBTB14,ZBTB38,ZBTB16,GAN" Domain IPR001675 Glyco_trans_29 InterPro 1.30E-03 1.00E+00 4.95E-02 4.75E-01 10 20 "ST3GAL5,ST8SIA3,ST3GAL6,ST6GALNAC3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" Domain PF00777 Glyco_transf_29 Pfam 1.30E-03 1.00E+00 4.95E-02 4.75E-01 10 20 "ST3GAL5,ST8SIA3,ST3GAL6,ST6GALNAC3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" Domain IPR027231 Semaphorin InterPro 1.30E-03 1.00E+00 4.95E-02 4.75E-01 10 20 "SEMA6A,SEMA7A,SEMA4G,SEMA3D,SEMA6C,SEMA4D,SEMA5B,SEMA6D,SEMA4A,SEMA3B" Domain PF00620 RhoGAP Pfam 1.31E-03 1.00E+00 4.95E-02 4.75E-01 22 63 "ABR,ARHGAP20,ARHGAP5,ARHGAP33,CHN1,CHN2,ARHGAP22,ARHGAP32,ARHGAP24,SRGAP3,FAM13A,DLC1,ARHGAP19,ARHGAP36,INPP5B,ARHGAP12,MYO9A,OCRL,OPHN1,PIK3R1,ARHGAP26,ARHGAP9" Domain IPR019804 Ras_G-nucl-exch_fac_CS InterPro 1.33E-03 1.00E+00 4.99E-02 4.79E-01 8 14 "RASGEF1C,RAPGEF4,RAPGEF1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR013032 EGF-like_CS InterPro 1.35E-03 1.00E+00 4.99E-02 4.79E-01 68 262 "LTBP4,CNTNAP1,TMEFF1,ASTN1,ADAM23,ADAM15,SLIT2,NRXN3,NRXN1,NRXN2,NRG2,TENM4,ATRNL1,VCAN,NCAN,CNTNAP2,EDIL3,CELSR3,TENM1,EPHA5,EPHB1,EFEMP1,CSPG5,DLL3,NRG3,MEGF11,MEGF10,TMEM8B,DNER,ADAM28,NTNG2,WIF1,LAMA2,MSANTD3-TMEFF1,CLEC18A,MATN2,MATN3,ADAM11,LRP1B,ADAM22,NELL1,NELL2,VWA2,FAT3,MASP1,RELN,LAMA1,FAT4,CRTAC1,EPHA10,CNTNAP3,PEAR1,SELL,NTNG1,BCAN,SLIT1,VWCE,TEK,CRB1,HHIP,THBS4,TIE1,TLL2,TNR,TMEFF2,VLDLR,CRB2,LRP8" Domain PF00617 RasGEF Pfam 1.37E-03 1.00E+00 4.99E-02 4.79E-01 13 30 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR001895 RASGEF_cat_dom InterPro 1.37E-03 1.00E+00 4.99E-02 4.79E-01 13 30 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain 1.10.840.10 - Gene3D 1.37E-03 1.00E+00 4.99E-02 4.79E-01 13 30 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain IPR023578 Ras_GEF_dom InterPro 1.37E-03 1.00E+00 4.99E-02 4.79E-01 13 30 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain SM00147 RasGEF SMART 1.37E-03 1.00E+00 4.99E-02 4.79E-01 13 30 "BCAR3,RASGEF1C,RASGRP1,RASGRP2,RAPGEF6,RAPGEF4,RAPGEF1,KNDC1,RASGEF1B,RALGDS,RASGRF1,RASGRF2,RGL1" Domain PF00122 E1-E2_ATPase Pfam 1.37E-03 1.00E+00 4.99E-02 4.79E-01 15 37 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP13A4,ATP2C1,ATP8A2,ATP8B4,ATP10B,ATP11A,ATP13A2" Domain IPR008250 ATPase_P-typ_transduc_dom_A InterPro 1.37E-03 1.00E+00 4.99E-02 4.79E-01 15 37 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP13A4,ATP2C1,ATP8A2,ATP8B4,ATP10B,ATP11A,ATP13A2" Pathway 1268763 Neuronal System BioSystems: REACTOME 6.54E-41 2.02E-37 2.02E-37 1.74E-36 170 351 "ABAT,KCNH8,SYN3,ACHE,ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,LRFN2,NLGN4X,AP2A1,AP2A2,BEGAIN,LRFN1,PPFIA4,PPFIA2,PPFIA1,APBA2,KCNAB2,EPB41L5,PPFIA3,CASK,BCHE,HCN2,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CACNB2,CACNB4,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,KCNAB3,DLGAP2,DLGAP1,CACNA2D2,CHRNA4,CHRNB2,DLGAP3,NRXN3,NRXN1,NRXN2,HOMER3,PICK1,AKAP5,SLC32A1,SIPA1L1,DLG2,DLG3,DLG4,SHANK1,ABCC9,EPB41,EPB41L1,EPB41L2,KCNMB2,NCALD,RTN3,CACNG3,CACNG2,PDLIM5,NPTN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,CPLX1,GLS,GLUL,KCNMB4,GNAL,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,GRM1,GRM5,LRRTM3,LRRTM1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,SYT9,DBNL,MYO6,HCN1,KCNK10,PDPK1,GNG2,NLGN3,PLCB2,PRKACB,PRKCB,PRKCG,PTPRD,RAB3A,RASGRF1,RASGRF2,RPS6KA2,LRRTM4,NLGN4Y,NLGN1,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,SHANK2,RIMS1,SNAP25,EPB41L3,STX1A,STXBP1,ABCC8,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SLC38A1,SLC17A7,KCNAB1" Pathway 1268766 Transmission across Chemical Synapses BioSystems: REACTOME 4.91E-24 1.51E-20 7.57E-21 6.51E-20 103 218 "ABAT,SYN3,ACHE,ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,AP2A1,AP2A2,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,BCHE,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CACNB2,CACNB4,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CACNA2D2,CHRNA4,CHRNB2,PICK1,AKAP5,SLC32A1,DLG3,DLG4,EPB41L1,NCALD,CACNG3,CACNG2,NPTN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,CPLX1,GLS,GLUL,GNAL,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,CACFD1,GRIN2C,GRIN2D,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,MYO6,PDPK1,GNG2,PLCB2,PRKACB,PRKCB,PRKCG,RAB3A,RASGRF1,RASGRF2,RPS6KA2,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,RIMS1,SNAP25,STX1A,STXBP1,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SLC38A1,SLC17A7" Pathway 1427849 Protein-protein interactions at synapses BioSystems: REACTOME 6.97E-17 2.15E-13 7.15E-14 6.16E-13 45 73 "LRFN2,NLGN4X,BEGAIN,LRFN1,APBA2,EPB41L5,CASK,DLGAP2,DLGAP1,DLGAP3,NRXN3,NRXN1,NRXN2,HOMER3,SIPA1L1,DLG2,DLG3,DLG4,SHANK1,EPB41,EPB41L1,EPB41L2,RTN3,PDLIM5,GRIA1,GRIA4,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,LRRTM3,LRRTM1,SYT9,DBNL,NLGN3,PTPRD,LRRTM4,NLGN4Y,NLGN1,SHANK2,EPB41L3,STX1A,STXBP1,SYT1" Pathway 1427850 Interactions of neurexins and neuroligins at synapses BioSystems: REACTOME 2.52E-16 7.76E-13 1.94E-13 1.67E-12 39 59 "NLGN4X,BEGAIN,APBA2,EPB41L5,CASK,DLGAP2,DLGAP1,DLGAP3,NRXN3,NRXN1,NRXN2,HOMER3,SIPA1L1,DLG2,DLG3,DLG4,SHANK1,EPB41,EPB41L1,EPB41L2,PDLIM5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,LRRTM3,LRRTM1,SYT9,DBNL,NLGN3,LRRTM4,NLGN4Y,NLGN1,SHANK2,EPB41L3,STX1A,STXBP1,SYT1" Pathway 1270303 Axon guidance BioSystems: REACTOME 1.77E-15 5.44E-12 1.09E-12 9.37E-12 173 554 "ACTN2,BRAP,UNC5A,AP2A1,AP2A2,SEMA6A,ALCAM,ANK1,ANK2,ANK3,SEMA7A,CNTNAP1,SHTN1,SPTBN4,ARRB1,ARRB2,NUMB,FGF17,NRP2,KSR1,CDK5R1,ARHGEF7,CACNA1I,CACNA1G,CACNA1D,CACNB2,CACNB4,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CDC42,SLIT2,CLTA,CLTB,CLTC,NGEF,CNTN1,COL4A5,COL9A1,COL9A2,COL9A3,NRG2,CRMP1,CSF2RA,NCAN,PLXNA4,DCC,SRGAP3,DLG3,DLG4,DNM1,DNM2,DPYSL2,DUSP9,RASGRP1,EFNA2,EFNA3,EFNB3,APH1A,EGFR,PLXNC1,RASA4,EPHA5,EPHB1,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,CAP2,AGAP2,EVL,SEMA4D,WDR83,DPYSL4,NRG3,ABLIM2,FYN,GAB1,CHL1,GAP43,GFRA1,GFRA2,RND1,GRB10,GRIN1,GRIN2C,GRIN2D,HSP90AA1,ITGAV,JAK1,JAK2,KCNQ2,KCNQ3,KIT,L1CAM,MARK3,SHC3,KITLG,GIT1,NCAM1,NF1,NRCAM,KSR2,TREM2,PAK3,PDGFRA,PIK3CD,PIK3R1,PLXNB1,PLXNB3,PPP2R5C,PPP2R5E,PPP5C,PRKACB,MAPK3,MAPK7,PSMA6,LAMA1,PSMD13,PTK2,RAP1GAP,RASGRF1,RASGRF2,RDX,RET,MYH14,ROBO1,ROBO2,EPHA10,RPS6KA2,SEMA6D,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,RASA3,ITSN1,SH3GL2,CNKSR2,ABLIM3,SLIT1,SCN3B,DOK5,UNC5B,SPTAN1,SPTB,NFASC,CLASP2,SEMA4A,ROBO3,UNC5D,CNTN2,CLASP1,ARHGEF12,TEK,TIAM1,DOK6,RGMB,TRIO,TRPC1,TRPC3,UBC,VAV2,DPYSL5,RGMA,PAK5,ST8SIA2" Pathway 1339115 Cardiac conduction BioSystems: REACTOME 8.37E-15 2.58E-11 4.29E-12 3.70E-11 65 142 "ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CACNA2D2,DMPK,ABCC9,CACNG7,CACNG3,CACNG2,FGF11,FGF12,FGF13,FGF14,AHCYL1,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNK3,FXYD7,FXYD6,NOS1,NPPA,NPR2,KCNK10,FXYD1,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A2,SLC8A1,SLC8A3,SLN,SCN3B,TRPC1,KCNE5,KCNK12" Pathway 213818 Glutamatergic synapse BioSystems: KEGG 6.32E-14 1.95E-10 2.78E-11 2.40E-10 55 114 "ADCY2,ADCY5,ADCY6,ADCY8,PLA2G4C,CACNA1A,CACNA1D,DLGAP1,HOMER3,DLG4,GRIN3A,SHANK1,GLS,GLUL,GNAO1,GNAS,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNJ3,GNG2,PLCB2,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SHANK2,PLCB1,TRPC1,SLC38A1,SLC17A7,SLC17A6" Pathway 1269868 Muscle contraction BioSystems: REACTOME 8.22E-14 2.53E-10 3.16E-11 2.73E-10 81 204 "ACTN2,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CACNA2D2,MYL6B,DMD,DMPK,ABCC9,CACNG7,SORBS3,CACNG3,CACNG2,FGF11,FGF12,FGF13,FGF14,SORBS1,AHCYL1,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ11,KCNK1,KCNK2,KCNK3,MYBPC1,MYH3,MYH6,MYL3,FXYD7,FXYD6,NOS1,NPPA,NPR2,KCNK10,TMOD2,FXYD1,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SLC8A2,SLC8A1,SLC8A3,SLN,SCN3B,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,TRPC1,KCNE5,KCNK12" Pathway 1268786 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell BioSystems: REACTOME 2.41E-13 7.42E-10 8.25E-11 7.10E-10 64 147 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,AP2A1,AP2A2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CHRNA4,CHRNB2,PICK1,AKAP5,DLG3,DLG4,EPB41L1,NCALD,CACNG3,CACNG2,NPTN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GNAL,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,MYO6,PDPK1,GNG2,PLCB2,PRKACB,PRKCB,PRKCG,RASGRF1,RASGRF2,RPS6KA2,ARHGEF9,PLCB1" Pathway P00037 Ionotropic glutamate receptor pathway PantherDB 1.24E-12 3.83E-09 3.83E-10 3.30E-09 30 46 "CACNA1A,CACNA1B,CACNA1E,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PICK1,GRIN3A,SHANK1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM2,GRM3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SNAP25,VAMP1,SLC17A6" Pathway 83065 Axon guidance BioSystems: KEGG 8.44E-12 2.60E-08 2.36E-09 2.04E-08 69 175 "UNC5A,SEMA6A,SEMA7A,LRRC4C,SEMA4G,BMP7,BMPR1B,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CDC42,CFL2,SLIT2,NGEF,PLXNA4,BOC,DCC,PARD6A,SRGAP3,DPYSL2,SEMA3D,EFNA2,EFNA3,EFNB3,PLXNC1,EPHA5,EPHB1,SEMA6C,SEMA4D,ABLIM2,FYN,NTNG2,RND1,L1CAM,PAK3,SSH1,SEMA5B,PIK3CD,PIK3R1,PLXNB1,PLXNB3,PPP3CA,PPP3CB,PPP3CC,PRKCZ,MAPK3,PTCH1,PTK2,RGS3,ROBO1,ROBO2,SEMA6D,NTNG1,ABLIM3,SLIT1,UNC5B,LRRC4,SEMA4A,ROBO3,UNC5D,ARHGEF12,PARD3,TRPC1,TRPC3,DPYSL5,SEMA3B,FZD3,PAK5" Pathway P00027 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway PantherDB 2.18E-11 6.71E-08 5.50E-09 4.74E-08 50 111 "ADORA1,ADORA2A,ADORA3,RGS11,RGS9,CACNA1A,CACNA1B,CACNA1E,ARHGEF1,CHRM1,CHRM4,CLTA,CLTB,CLTC,RGS6,GPSM1,DRD1,RASGRP1,RGS17,RASGRP2,DNAJC27,GNAO1,GNG3,GNG4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GPR45,KCNJ3,KCNJ5,KCNJ9,OPRL1,GNG2,GPSM2,PLCB2,PRKCB,PRKCG,PRKCZ,RAP1GAP,RGS3,RGS4,RGS7,RGS10,RGS12,SSTR1,SSTR2,PLCB1" Pathway 83050 Calcium signaling pathway BioSystems: KEGG 2.32E-11 7.15E-08 5.50E-09 4.74E-08 70 182 "ADCY2,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CCKBR,P2RX6,CD38,CHRM1,DRD1,EDNRA,EDNRB,EGFR,ERBB2,ERBB4,PTK2B,GNAL,GNAS,PLCD4,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,HTR2A,HTR5A,MYLK2,ITPKA,ITPKB,NOS1,OXTR,P2RX7,PDE1A,PDE1C,PDE1B,PDGFRA,PHKG1,PLCB2,PLCD1,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,PTAFR,RYR1,RYR3,SLC8A2,SLC8A1,SLC8A3,PLCB1,TACR1,SPHK2" Pathway 1270323 L1CAM interactions BioSystems: REACTOME 3.26E-11 1.01E-07 7.18E-09 6.18E-08 47 102 "AP2A1,AP2A2,ALCAM,ANK1,ANK2,ANK3,CNTNAP1,SHTN1,SPTBN4,NUMB,NRP2,CLTA,CLTC,CNTN1,NCAN,DLG3,DLG4,DNM1,DNM2,DPYSL2,EGFR,FGFR1,CHL1,GAP43,ITGAV,KCNQ2,KCNQ3,L1CAM,NCAM1,NRCAM,MAPK3,LAMA1,RDX,RPS6KA2,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SH3GL2,SCN3B,SPTAN1,SPTB,NFASC,CNTN2,VAV2" Pathway 552665 Morphine addiction BioSystems: KEGG 8.10E-11 2.50E-07 1.66E-08 1.43E-07 43 91 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ARRB1,ARRB2,PDE8B,CACNA1A,CACNA1B,SLC32A1,DRD1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GNAO1,GNAS,GNG3,GNG4,GRK4,KCNJ3,KCNJ5,KCNJ9,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,GNG2,PRKACB,PRKCB,PRKCG" Pathway 169346 Regulation of RAC1 activity BioSystems: Pathway Interaction Database 1.67E-10 5.15E-07 3.22E-08 2.77E-07 25 39 "ABR,ARHGDIA,ARHGEF7,KALRN,ARHGEF25,ARHGEF2,CHN1,CHN2,NGEF,ARHGEF6,ELMO1,TIAM2,DOCK2,ABI1,EPS8,RAP1GDS1,RASGRF1,RASGRF2,PREX2,ARHGAP9,TIAM1,TRIO,VAV1,VAV2,SPATA13" Pathway 1268821 Potassium Channels BioSystems: REACTOME 8.70E-10 2.68E-06 1.58E-07 1.36E-06 44 100 "KCNH8,KCNAB2,HCN2,KCNAB3,ABCC9,KCNMB2,GABBR1,KCNMB4,GNG3,GNG4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,HCN1,KCNK10,GNG2,ABCC8,KCNAB1" Pathway 537443 Retrograde endocannabinoid signaling BioSystems: KEGG 1.28E-09 3.94E-06 2.19E-07 1.88E-06 44 101 "ABHD6,ADCY2,ADCY5,ADCY6,ADCY8,CACNA1A,CACNA1B,CACNA1D,CNR1,SLC32A1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GNAO1,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRM1,GRM5,KCNJ3,KCNJ5,KCNJ9,GNG2,PLCB2,PRKACB,PRKCB,PRKCG,MAPK3,MAPK8,MAPK9,MAPK10,MAPK12,RIMS1,PLCB1,SLC17A7,SLC17A6" Pathway P00039 Metabotropic glutamate receptor group III pathway PantherDB 3.61E-09 1.11E-05 5.85E-07 5.04E-06 32 64 "CACNA1A,CACNA1B,CACNA1E,GRIN3A,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GRM7,GRM8,PRKACB,PRKAR1B,STX1B,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SNAP25,STX1A,VAMP1,SLC17A7" Pathway 908257 Adrenergic signaling in cardiomyocytes BioSystems: KEGG 4.27E-09 1.32E-05 6.58E-07 5.66E-06 55 144 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CACNA2D2,CREM,CREB5,CACNG7,CACNG3,CACNG2,GNAS,RAPGEF4,MYH6,MYH7,MYL3,PLCB2,PPP1R1A,PPP2R2B,PPP2R2C,PPP2R5C,PPP2R5E,PRKACB,MAPK3,PPP2R3C,MAPK12,SCN4B,SCN7A,SLC8A1,PLCB1,PIK3R5,TPM1,TPM2,TPM3,TPM4" Pathway 1339121 Ion homeostasis BioSystems: REACTOME 6.92E-09 2.13E-05 1.02E-06 8.74E-06 29 56 "ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DMPK,ABCC9,AHCYL1,KCNJ11,FXYD7,FXYD6,NOS1,FXYD1,RYR1,RYR3,SLC8A2,SLC8A1,SLC8A3,SLN,TRPC1" Pathway P00057 Wnt signaling pathway PantherDB 1.20E-08 3.70E-05 1.65E-06 1.42E-05 94 305 "ARID1A,AXIN2,FZD9,PCDH19,PCDH10,EP400,MYH7B,APC,ARRB1,ARRB2,PCDHGB4,BMPR1B,BTRC,CDH2,CDH8,CDH10,CDH18,SMARCAL1,CHD1L,CSNK1E,CSNK1G3,PYGO1,EDN1,CELSR3,EN2,CDHR1,APC2,SRCAP,PCDH11X,GNG3,GNG4,NKD1,CDH20,SMAD1,CTNNA3,MYCN,MYH3,MYH6,MYH7,PCDHGC3,PCDH8,PCDH9,GNG2,PLCB2,PCDH18,FAT3,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PRKCB,PRKCG,PRKCZ,ANKRD6,SMARCA4,SMARCC2,SMARCD3,SMARCE1,PLCB1,FBXW11,TBL1X,TCF7L2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,WNT7A,PCDH20,PCDH15,FZD3" Pathway 1268768 Neurotransmitter Release Cycle BioSystems: REACTOME 1.23E-08 3.79E-05 1.65E-06 1.42E-05 27 51 "ABAT,SYN3,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,SLC32A1,GAD1,GAD2,CPLX1,GLS,RAB3A,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,RIMS1,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYT1,SLC17A7" Pathway 1268771 Glutamate Neurotransmitter Release Cycle BioSystems: REACTOME 1.56E-08 4.79E-05 2.00E-06 1.72E-05 17 24 "PPFIA4,PPFIA2,PPFIA1,PPFIA3,CPLX1,GLS,RAB3A,SLC1A2,SLC1A3,SLC1A6,SLC1A7,RIMS1,SNAP25,STX1A,STXBP1,SYT1,SLC17A7" Pathway 583255 Nicotine addiction BioSystems: KEGG 1.85E-08 5.70E-05 2.21E-06 1.90E-05 23 40 "CACNA1A,CACNA1B,CHRNA4,CHRNB2,SLC32A1,GRIN3A,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,SLC17A7,SLC17A6" Pathway 1269443 Signalling by NGF BioSystems: REACTOME 1.86E-08 5.74E-05 2.21E-06 1.90E-05 134 483 "ABR,ACTN2,PLEKHG5,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,BRAP,ADORA2A,KIDINS220,AP2A1,AP2A2,FGD2,TNRC6C,SPTBN4,ARHGDIA,ARRB1,ARRB2,FGF17,KSR1,ARHGEF7,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,ARHGEF1,ARHGEF2,CLTA,CLTC,NGEF,ARHGEF6,MAGED1,NRG2,CSF2RA,ARHGEF10,ARHGEF4,TIAM2,DLG4,DNM1,DNM2,DUSP9,RASGRP1,APH1A,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,RAPGEF1,GRIN1,GRIN2C,GRIN2D,LINGO1,JAK1,JAK2,KIT,MAG,PIK3AP1,MARK3,SHC3,MEF2C,KITLG,MOV10,NCAM1,NF1,NTRK2,KSR2,OMG,PCSK5,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK7,MAPK8,PSMA6,PSMD13,PTK2,RALGDS,RASGRF1,RASGRF2,RET,ARHGEF10L,RIT2,RPS6KA2,MAPK12,RASA3,ITSN1,SH3GL2,CNKSR2,ARHGEF40,SPTAN1,SPTB,FGD4,ARHGEF9,MLST8,MCF2L,ARHGEF12,TEK,ITGB3BP,TIAM1,TRIO,TSC2,UBC,VAV1,VAV2,RICTOR,RTN4" Pathway 377263 GABAergic synapse BioSystems: KEGG 2.27E-08 6.99E-05 2.56E-06 2.21E-05 38 88 "ABAT,ADCY2,ADCY5,ADCY6,ADCY8,SLC12A5,CACNA1A,CACNA1B,CACNA1D,HAP1,SLC32A1,GPHN,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLS,GLUL,GNAO1,GNG3,GNG4,GABARAPL2,GNG2,PLCL1,PRKACB,PRKCB,PRKCG,SLC6A1,SLC6A11,SLC38A1" Pathway 1269950 Ion channel transport BioSystems: REACTOME 2.33E-08 7.18E-05 2.56E-06 2.21E-05 70 209 "TTYH1,ASIC2,ASIC1,UNC79,ASPH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V1G2,ATP6V0A1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ASIC3,CLCN3,CLCN4,SGK2,ATP8A1,SLC9B2,ATP13A4,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,ATP8A2,GLRB,TTYH2,FXYD7,FXYD6,BEST3,NALCN,FXYD1,ATP8B4,RYR1,RYR3,SCNN1D,ASIC4,SGK1,SLN,UNC80,ATP10B,ARHGEF9,ATP11A,ANO4,TPCN2,ATP13A2,TRPC1,TRPC3,TRPM2,ANO5,SGK3,UBC,BEST1,ATP6V0E2,WNK1,WNK3,WNK2" Pathway P00012 Cadherin signaling pathway PantherDB 3.24E-08 9.96E-05 3.39E-06 2.92E-05 57 159 "FZD9,PCDH19,PCDH10,PCDHGB4,CDH2,CDH8,CDH10,CDH18,CTNND1,CTNND2,CELSR3,EGFR,ERBB2,ERBB4,CDHR1,FER,FYN,PCDH11X,CDH20,CTNNA3,PCDHGC3,PCDH8,PCDH9,PCDH18,FAT3,TCF7L2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,WNT7A,PCDH20,PCDH15,FZD3" Pathway 698773 Circadian entrainment BioSystems: KEGG 3.30E-08 1.02E-04 3.39E-06 2.92E-05 40 96 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,CACNA1I,CACNA1G,CACNA1D,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,NOS1AP,GNAO1,GNAS,GNG3,GNG4,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,GUCY1A2,GUCY1A1,GUCY1B1,KCNJ3,KCNJ5,KCNJ9,NOS1,GNG2,PLCB2,PRKACB,PRKCB,PRKCG,MAPK3,RYR1,RYR3,PLCB1" Pathway 1339117 Phase 0 - rapid depolarisation BioSystems: REACTOME 3.77E-08 1.16E-04 3.75E-06 3.23E-05 25 47 "CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CACNA2D2,CACNG7,CACNG3,CACNG2,FGF11,FGF12,FGF13,FGF14,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCN3B" Pathway 1268770 Serotonin Neurotransmitter Release Cycle BioSystems: REACTOME 4.36E-08 1.34E-04 4.20E-06 3.62E-05 14 18 "SYN3,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CPLX1,RAB3A,RIMS1,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYT1" Pathway P05734 Synaptic vesicle trafficking PantherDB 6.28E-08 1.93E-04 5.70E-06 4.91E-05 16 23 "SYT6,RIMS2,SYT15,STX2,SYT3,RAB3A,STX1B,RIMS1,STX1A,STXBP1,SYT11,VAMP1,SYN1,SYP,SYT1,SYT5" Pathway P00026 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway PantherDB 6.29E-08 1.94E-04 5.70E-06 4.91E-05 54 150 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,ARRB1,ARRB2,RGS11,RGS9,CHRM1,CHRM4,CLTA,CLTB,CLTC,CREM,RGS6,GPSM1,DRD1,RGS17,GNAL,GNG3,GNG4,GRK4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,HTR2A,HTR5A,KCNJ3,KCNJ5,KCNJ9,OPRL1,GNG2,PHKG1,GPSM2,PRKACB,PRKAR1B,PYGM,RGS3,RGS4,RGS7,RGS10,RGS12,SSTR1,SSTR2" Pathway 777534 Insulin secretion BioSystems: KEGG 9.66E-08 2.97E-04 8.50E-06 7.32E-05 36 85 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CACNA1D,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CREB5,RIMS2,KCNMB2,GCK,KCNMB4,GNAS,PCLO,RAPGEF4,KCNJ11,KCNMA1,KCNN1,KCNN2,KCNN3,PLCB2,PRKACB,PRKCB,PRKCG,RAB3A,SNAP25,STX1A,ABCC8,PLCB1" Pathway 952859 Oxytocin signaling pathway BioSystems: KEGG 1.34E-07 4.13E-04 1.15E-05 9.88E-05 54 153 "ADCY2,ADCY5,ADCY6,ADCY8,PLA2G4C,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD38,CACNA2D2,MYL6B,RCAN1,CACNG7,EGFR,CACNG3,CACNG2,PRKAG2,CAMKK2,GNAO1,GNAS,GUCY1A2,GUCY1A1,GUCY1B1,MYLK2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,MEF2C,NPR2,OXTR,PLCB2,PPP3CA,PPP3CB,PPP3CC,PRKAB2,PRKACB,PRKCB,PRKCG,MAPK3,MAPK7,RYR1,RYR3,PLCB1,PIK3R5,TRPM2,CAMK1G" Pathway 469199 Dopaminergic synapse BioSystems: KEGG 1.38E-07 4.26E-04 1.15E-05 9.91E-05 48 130 "ADCY5,ARNTL,ARRB2,CACNA1A,CACNA1B,CACNA1D,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CLOCK,CREB5,CALY,DRD1,PPP1R1B,GNAL,GNAO1,GNAS,GNG3,GNG4,GRIA1,GRIA2,GRIA4,KCNJ3,KCNJ5,KCNJ9,KIF5A,KIF5C,MAOB,GNG2,PLCB2,PPP2R2B,PPP2R2C,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK8,MAPK9,MAPK10,PPP2R3C,MAPK12,PLCB1" Pathway 1017634 cAMP signaling pathway BioSystems: KEGG 1.71E-07 5.26E-04 1.38E-05 1.19E-04 65 198 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AMH,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,HCN2,CACNA1D,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CHRM1,CNGA3,CREB5,GRIN3A,DRD1,EDNRA,PPP1R1B,GABBR1,GNAS,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,AFDN,NPY,OXTR,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PIK3CD,PIK3R1,FXYD1,PPARA,PRKACB,MAPK3,MAPK8,MAPK9,MAPK10,PTCH1,SSTR1,SSTR2,HHIP,TIAM1,VAV1,VAV2,VIPR2" Pathway 1270349 LGI-ADAM interactions BioSystems: REACTOME 2.51E-07 7.73E-04 1.98E-05 1.71E-04 12 15 "ADAM23,LGI1,DLG4,CACNG3,CACNG2,ADAM11,ADAM22,LGI2,STX1B,LGI3,STX1A,LGI4" Pathway 1270325 Interaction between L1 and Ankyrins BioSystems: REACTOME 2.75E-07 8.47E-04 2.07E-05 1.78E-04 18 30 "ANK1,ANK2,ANK3,SPTBN4,KCNQ2,KCNQ3,L1CAM,NRCAM,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,SCN3B,SPTAN1,SPTB,NFASC" Pathway 137990 Regulation of CDC42 activity BioSystems: Pathway Interaction Database 2.75E-07 8.47E-04 2.07E-05 1.78E-04 18 30 "BCAR3,APC,ARHGDIA,DOCK11,ARHGEF7,ARHGEF25,CDC42,NGEF,ARHGEF6,GIT1,ITSN1,DOCK10,ARHGEF9,MCF2L,DNMBP,DOCK9,VAV2,SPATA13" Pathway 1268772 Dopamine Neurotransmitter Release Cycle BioSystems: REACTOME 5.99E-07 1.84E-03 4.39E-05 3.78E-04 15 23 "SYN3,PPFIA4,PPFIA2,PPFIA1,PPFIA3,CASK,CPLX1,RAB3A,RIMS1,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYT1" Pathway 1427858 Clathrin-mediated endocytosis BioSystems: REACTOME 8.39E-07 2.59E-03 6.01E-05 5.18E-04 48 137 "ADRB2,AP2A1,AP2A2,AMPH,BIN1,ARRB1,ARRB2,SYNJ1,SYNJ2,HIP1R,REPS2,EPS15L1,CLTA,CLTB,CLTC,GAPVD1,DNAJC6,COPS7A,KIAA0319,SNAP91,DNM1,DNM2,EGFR,COPS4,SGIP1,COPS8,STON1,PACSIN2,AGFG1,SYT9,OCRL,PIK3C2A,EPN1,PACSIN1,SH3KBP1,RAB5B,ITSN1,SH3GL2,SH3GL3,EPN2,ARFGAP1,FNBP1,FCHO1,SYT11,SYT1,TACR1,TF,UBC" Pathway 1268795 Trafficking of AMPA receptors BioSystems: REACTOME 1.04E-06 3.21E-03 7.14E-05 6.15E-04 18 32 "AP2A1,AP2A2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PICK1,AKAP5,DLG4,EPB41L1,CACNG3,CACNG2,GRIA1,GRIA2,GRIA4,MYO6,PRKCB,PRKCG" Pathway 1268794 "Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity" BioSystems: REACTOME 1.04E-06 3.21E-03 7.14E-05 6.15E-04 18 32 "AP2A1,AP2A2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PICK1,AKAP5,DLG4,EPB41L1,CACNG3,CACNG2,GRIA1,GRIA2,GRIA4,MYO6,PRKCB,PRKCG" Pathway 547607 Amphetamine addiction BioSystems: KEGG 1.41E-06 4.34E-03 9.44E-05 8.13E-04 29 68 "ADCY5,CACNA1D,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CREB5,GRIN3A,DRD1,PPP1R1B,GNAS,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,MAOB,PDYN,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,STX1A,ARC,SIRT1" Pathway 1268774 "GABA synthesis, release, reuptake and degradation" BioSystems: REACTOME 1.54E-06 4.75E-03 1.01E-04 8.70E-04 13 19 "ABAT,SLC32A1,GAD1,GAD2,CPLX1,RAB3A,SLC6A1,SLC6A11,RIMS1,SNAP25,STX1A,STXBP1,SYT1" Pathway 1268799 "Unblocking of NMDA receptor, glutamate binding and activation" BioSystems: REACTOME 2.40E-06 7.38E-03 1.54E-04 1.32E-03 12 17 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D" Pathway PW:0000031 purine metabolic Pathway Ontology 2.89E-06 8.91E-03 1.82E-04 1.57E-03 21 43 "ADCY2,ADCY5,ADCY6,ADCY8,AK2,AMPD3,GDA,GART,GUCY1A2,GUCY1A1,GUCY1B1,NPR2,PDE1A,PDE2A,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PKM,POLR2F" Pathway 213307 Endocrine and other factor-regulated calcium reabsorption BioSystems: KEGG 4.11E-06 1.27E-02 2.53E-04 2.18E-03 22 47 "ADCY6,AP2A1,AP2A2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2B1,CALB1,CLTA,CLTB,CLTC,DNM1,DNM2,GNAS,PLCB2,PRKACB,PRKCB,PRKCG,PTH1R,SLC8A1,PLCB1" Pathway 1269508 Rho GTPase cycle BioSystems: REACTOME 5.23E-06 1.61E-02 3.16E-04 2.72E-03 48 145 "ABR,PLEKHG5,ARHGAP20,FGD2,ARHGAP5,ARHGDIA,ARHGDIG,ARHGEF7,KALRN,ARHGEF1,ARHGEF2,CDC42,ARHGAP33,CHN1,CHN2,ARHGAP22,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,ARHGAP32,ARHGAP24,TIAM2,RHOBTB1,SRGAP3,FAM13A,DLC1,ARHGAP19,ARHGAP36,INPP5B,ARHGAP12,MYO9A,OCRL,OPHN1,RASGRF2,ARHGEF10L,ITSN1,ARHGEF40,ARHGAP26,FGD4,ARHGEF9,MCF2L,ARHGEF12,ARHGAP9,TIAM1,TRIO,VAV1,VAV2" Pathway 1269951 Ion transport by P-type ATPases BioSystems: REACTOME 5.90E-06 1.82E-02 3.50E-04 3.01E-03 25 58 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ATP8A1,ATP13A4,ATP2C1,ATP8A2,FXYD7,FXYD6,FXYD1,ATP8B4,SLN,ATP10B,ATP11A,ATP13A2" Pathway PW:0000674 insulin secretion pathway Pathway Ontology 6.02E-06 1.85E-02 3.50E-04 3.01E-03 12 18 "CACNA1A,CACNA1D,CDC42,GCK,KCNB1,KCNJ11,SYT9,RAB3A,SNAP25,STX1A,STXBP1,ABCC8" Pathway 1269877 Membrane Trafficking BioSystems: REACTOME 7.06E-06 2.17E-02 3.99E-04 3.43E-03 151 614 "SYS1,ADRB2,AP2A1,AP2A2,AP1B1,TBC1D14,PLA2G6,AMPH,KIF6,BIN1,ANK1,ANK2,ANK3,MYH7B,CNIH2,ALS2,APP,MADD,SPTBN4,ARRB1,ARRB2,DYNLL1,STX16,KIF1A,SYNJ1,SYNJ2,AP1M1,CALM1,HIP1R,AP4M1,REPS2,COPB2,CHM,EPS15L1,RAB33A,COG1,CLTA,CLTB,CLTC,SEC24C,PUM1,USP6NL,GAPVD1,KIF26A,DNAJC6,DCTN1,CNIH3,COPS7A,KIAA0319,BLOC1S6,SNAP91,KIF19,SEC16A,RAB39B,DNM1,TRAPPC9,DYNC1I1,DNM2,OPTN,EGFR,COPS4,DCTN4,RABEPK,RAB9B,DENND4A,F5,F8,CLVS1,TBC1D16,SEC24B,PRKAG2,SGIP1,DCTN2,ARFGAP2,AP4B1,DENND2A,GJB1,COPS8,RAB30,GOLGB1,STON1,GRIA1,KIF3A,AP4S1,PACSIN2,GABARAPL2,AGFG1,RAB41,CLVS2,KIF2A,KIF5A,KLC1,MAN2A2,SYT9,MIA2,MYH3,MYH6,MYH7,MYO5A,MYO6,TBC1D25,OCRL,PIK3C2A,EPN1,PACSIN1,SH3KBP1,PRKAB2,RAB39A,RAB3A,RAB3IL1,RAB5B,TRAPPC13,SBF1,KIF27,COPZ1,KIF21A,ITSN1,SH3GL2,SH3GL3,KIF16B,SEC31A,EPN2,RAB3GAP1,NAPB,ARFGAP1,MYH15,KIF21B,FNBP1,SPTAN1,SPTB,KIF1B,ST5,FCHO1,SYT11,SYT1,ANKRD28,TACR1,EXOC7,TF,AP4E1,TJP1,TPD52,TSC1,TSC2,UBC,GORASP1,TBC1D15,KLC2,LMAN2L,HPS4,GJC2" Pathway 1269448 NRAGE signals death through JNK BioSystems: REACTOME 7.12E-06 2.19E-02 3.99E-04 3.43E-03 26 62 "ABR,PLEKHG5,FGD2,ARHGEF7,KALRN,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF10,ARHGEF4,TIAM2,MAPK8,RASGRF2,ARHGEF10L,ITSN1,ARHGEF40,FGD4,ARHGEF9,MCF2L,ARHGEF12,TIAM1,TRIO,VAV1,VAV2" Pathway 373900 Synaptic vesicle cycle BioSystems: KEGG 1.01E-05 3.11E-02 5.50E-04 4.74E-03 26 63 "AP2A1,AP2A2,ATP6V1G2,ATP6V0A1,CACNA1A,CACNA1B,CLTA,CLTB,CLTC,SLC32A1,DNM1,DNM2,STX2,ATP6V1H,CPLX2,CPLX1,RAB3A,STX1B,RIMS1,SNAP25,STX1A,STXBP1,SYT1,ATP6V0E2,SLC17A7,SLC17A6" Pathway 1268813 GABA receptor activation BioSystems: REACTOME 1.02E-05 3.14E-02 5.50E-04 4.74E-03 24 56 "ADCY2,ADCY5,ADCY6,ADCY8,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GNAL,GNG3,GNG4,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,GNG2,ARHGEF9" Pathway 1268802 Ras activation uopn Ca2+ infux through NMDA receptor BioSystems: REACTOME 1.37E-05 4.22E-02 7.27E-04 6.26E-03 12 19 "ACTN2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D,RASGRF1,RASGRF2" Pathway SMP00375 Verapamil Pathway SMPDB 1.47E-05 4.51E-02 7.52E-04 6.47E-03 24 57 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CALM1,CACNA2D2,ABCC9,EDNRA,EDNRB,MYLK2,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,MYH6,MYL3,SLC8A1,ABCC8,TPM1,TPM3" Pathway SMP00359 Diltiazem Pathway SMPDB 1.47E-05 4.51E-02 7.52E-04 6.47E-03 24 57 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CALM1,CACNA2D2,ABCC9,EDNRA,EDNRB,MYLK2,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,MYH6,MYL3,SLC8A1,ABCC8,TPM1,TPM3" Pathway 1269460 NGF signalling via TRKA from the plasma membrane BioSystems: REACTOME 1.60E-05 4.92E-02 8.06E-04 6.94E-03 102 390 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,BRAP,ADORA2A,KIDINS220,AP2A1,AP2A2,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,CLTA,CLTC,NRG2,CSF2RA,DLG4,DNM1,DNM2,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,RAPGEF1,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,PIK3AP1,MARK3,SHC3,MEF2C,KITLG,MOV10,NCAM1,NF1,NTRK2,KSR2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,MAPK7,PSMA6,PSMD13,PTK2,RALGDS,RASGRF1,RASGRF2,RET,RIT2,RPS6KA2,MAPK12,RASA3,SH3GL2,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC2,UBC,VAV1,RICTOR" Pathway 868086 Rap1 signaling pathway BioSystems: KEGG 1.64E-05 5.05E-02 8.15E-04 7.01E-03 62 210 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,FGF17,CALM1,KRIT1,CDC42,MAGI1,CNR1,CSF1,CSF1R,SIPA1L1,CTNND1,DOCK4,MAGI2,PARD6A,EFNA2,EFNA3,EGFR,RASGRP2,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,FLT1,FYB1,RAPGEF6,GNAO1,GNAS,LPAR4,RAPGEF4,RAPGEF1,GRIN1,IGF1,ITGAM,KIT,KITLG,AFDN,P2RY1,PDGFRA,PIK3CD,PIK3R1,PLCB2,PRKCB,PRKCG,PRKCZ,MAPK3,RALGDS,RAP1GAP,MAPK12,MRAS,MAGI3,PLCB1,TEK,TIAM1,PARD3,VAV2" Pathway PW:0000543 protein kinase A (PKA) signaling Pathway Ontology 1.67E-05 5.14E-02 8.15E-04 7.02E-03 21 47 "ADCY2,ADCY5,ADCY6,ADCY8,PDE8B,AKAP7,AKAP6,AKAP5,AKAP12,AKAP3,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,PRKAR1B" Pathway 1269876 Vesicle-mediated transport BioSystems: REACTOME 2.11E-05 6.50E-02 1.02E-03 8.75E-03 158 660 "SYS1,ADRB2,AP2A1,AP2A2,AP1B1,TBC1D14,PLA2G6,AMPH,KIF6,BIN1,ANK1,ANK2,ANK3,MYH7B,CNIH2,ALS2,APP,MADD,SPTBN4,ARRB1,ARRB2,DYNLL1,STX16,KIF1A,SYNJ1,SYNJ2,AP1M1,CALM1,HIP1R,SCARB1,AP4M1,REPS2,COPB2,CHM,EPS15L1,RAB33A,COG1,CLTA,CLTB,CLTC,SEC24C,PUM1,USP6NL,GAPVD1,KIF26A,DNAJC6,DCTN1,CNIH3,COPS7A,KIAA0319,BLOC1S6,SNAP91,KIF19,SEC16A,RAB39B,DNM1,TRAPPC9,DYNC1I1,DNM2,OPTN,EGFR,COPS4,DCTN4,RABEPK,RAB9B,DENND4A,F5,F8,CLVS1,TBC1D16,SEC24B,PRKAG2,SGIP1,DCTN2,ARFGAP2,AP4B1,DENND2A,GJB1,COPS8,RAB30,GOLGB1,STON1,GRIA1,KIF3A,AP4S1,HBA1,PACSIN2,GABARAPL2,HP,HPR,AGFG1,HSP90AA1,RAB41,CLVS2,KIF2A,KIF5A,KLC1,MAN2A2,SYT9,MIA2,MSR1,MYH3,MYH6,MYH7,MYO5A,MYO6,TBC1D25,OCRL,PIK3C2A,EPN1,PACSIN1,SH3KBP1,PRKAB2,RAB39A,MASP1,RAB3A,RAB3IL1,RAB5B,TRAPPC13,SBF1,KIF27,COPZ1,KIF21A,ITSN1,SH3GL2,SH3GL3,KIF16B,SEC31A,EPN2,RAB3GAP1,NAPB,ARFGAP1,MYH15,KIF21B,FNBP1,SPTAN1,SPTB,KIF1B,ST5,FCHO1,SYT11,SYT1,ANKRD28,TACR1,EXOC7,TF,AP4E1,TJP1,TPD52,TSC1,TSC2,UBC,GORASP1,TBC1D15,KLC2,LMAN2L,HPS4,GJC2" Pathway 1268798 Activation of NMDA receptor upon glutamate binding and postsynaptic events BioSystems: REACTOME 2.22E-05 6.84E-02 1.03E-03 8.84E-03 19 41 "ACTN2,ADCY8,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,PDPK1,PRKACB,RASGRF1,RASGRF2,RPS6KA2" Pathway 1268811 Activation of Ca-permeable Kainate Receptor BioSystems: REACTOME 2.23E-05 6.88E-02 1.03E-03 8.84E-03 9 12 "CALM1,DLG3,DLG4,NCALD,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pathway 1268809 Ionotropic activity of Kainate Receptors BioSystems: REACTOME 2.23E-05 6.88E-02 1.03E-03 8.84E-03 9 12 "CALM1,DLG3,DLG4,NCALD,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pathway 1268773 Acetylcholine Neurotransmitter Release Cycle BioSystems: REACTOME 2.29E-05 7.06E-02 1.04E-03 8.94E-03 11 17 "PPFIA4,PPFIA2,PPFIA1,PPFIA3,CPLX1,RAB3A,RIMS1,SNAP25,STX1A,STXBP1,SYT1" Pathway 1269903 Transmembrane transport of small molecules BioSystems: REACTOME 3.31E-05 1.02E-01 1.48E-03 1.27E-02 161 680 "TTYH1,ABCF1,ASIC2,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,ADD2,ADD3,SLC12A5,SLC24A4,SLC44A5,ABCD2,UNC79,AQP4,AQP6,ASPH,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ATP6V1G2,ATP6V0A1,AZGP1,NIPA1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SLC5A11,ASIC3,SLC22A6,CLCN3,CLCN4,SLC24A2,ABCG2,SLC4A7,SLC4A8,CP,SLC32A1,ABCG1,HEPH,POM121,SLC29A4,SLC12A6,SLC25A18,ABCC5,ABCC9,SGK2,DMTN,SLC43A2,ABCA8,ATP8A1,SLC9B2,ATP13A4,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,ATP8A2,GCK,GLRB,OS9,GNAS,GNG3,GNG4,SLC2A6,KCNJ11,TTYH2,AQP11,FXYD7,FXYD6,SLCO1C1,SLC11A2,GNG2,BEST3,ABCB1,NALCN,FXYD1,PRKACB,PRKAR1B,SLC26A11,PSMA6,PSMD13,SLC6A15,RNASEL,ATP8B4,RYR1,RYR3,SCNN1D,ASIC4,SGK1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,SLC6A1,SLC6A7,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SLN,UNC80,ATP10B,ABCC8,ARHGEF9,ATP11A,ANO4,TPCN2,AHCYL2,ATP13A2,TF,SLC44A1,TRPC1,TRPC3,TRPM2,ANO5,SGK3,UBC,BEST1,SLC13A3,SLC47A2,ATP6V0E2,SLC30A3,WNK1,SLC38A1,SLC17A7,WNK3,WNK2,SLC17A6,NUP214,AAAS,SLC4A10" Pathway 1269447 "Cell death signalling via NRAGE, NRIF and NADE" BioSystems: REACTOME 3.44E-05 1.06E-01 1.51E-03 1.30E-02 29 78 "ABR,PLEKHG5,FGD2,ARHGEF7,KALRN,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF10,ARHGEF4,TIAM2,APH1A,MAPK8,RASGRF2,ARHGEF10L,ITSN1,ARHGEF40,FGD4,ARHGEF9,MCF2L,ARHGEF12,ITGB3BP,TIAM1,TRIO,UBC,VAV1,VAV2" Pathway 1269579 G alpha (12/13) signalling events BioSystems: REACTOME 3.90E-05 1.20E-01 1.69E-03 1.46E-02 32 90 "ABR,PLEKHG5,ADRA1D,ADRA1B,FGD2,ARHGEF7,KALRN,ARHGEF1,ARHGEF2,CDC42,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,GNG3,GNG4,GNG2,PIK3R1,PLXNB1,RASGRF2,ARHGEF10L,ITSN1,ARHGEF40,FGD4,ARHGEF9,MCF2L,ARHGEF12,TIAM1,TRIO,VAV1,VAV2" Pathway 1268769 Norepinephrine Neurotransmitter Release Cycle BioSystems: REACTOME 4.95E-05 1.52E-01 2.11E-03 1.82E-02 11 18 "PPFIA4,PPFIA2,PPFIA1,PPFIA3,CPLX1,RAB3A,RIMS1,SNAP25,STX1A,STXBP1,SYT1" Pathway 1269341 Platelet homeostasis BioSystems: REACTOME 5.01E-05 1.54E-01 2.11E-03 1.82E-02 32 91 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,P2RX6,KCNMB2,MRVI1,FGR,KCNMB4,GNAS,GNG3,GNG4,GUCY1A2,GUCY1A1,GUCY1B1,KCNMA1,NOS1,P2RX7,PDE1A,PDE2A,PDE3A,PDE3B,PDE1B,GNG2,PPP2R5C,PPP2R5E,SLC8A2,SLC8A1,SLC8A3,TRPC3,LRP8" Pathway 1269343 Nitric oxide stimulates guanylate cyclase BioSystems: REACTOME 5.85E-05 1.80E-01 2.42E-03 2.09E-02 13 24 "KCNMB2,MRVI1,KCNMB4,GUCY1A2,GUCY1A1,GUCY1B1,KCNMA1,NOS1,PDE1A,PDE2A,PDE3A,PDE3B,PDE1B" Pathway 1269480 Signaling by VEGF BioSystems: REACTOME 5.91E-05 1.82E-01 2.42E-03 2.09E-02 89 341 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,NRP2,KSR1,WASF1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CDC42,NRG2,CSF2RA,CTNND1,CYBB,ELMO1,DLG4,ABI1,DUSP9,RASGRP1,EGFR,ABI2,RASA4,ERBB2,ERBB4,PTK2B,FGF1,FGFR1,FGFR3,BAIAP2,FLT1,WDR83,NRG3,FYN,AHCYL1,NCKAP1,WASF3,GFRA1,GFRA2,GRIN1,GRIN2C,GRIN2D,NCKAP1L,HSP90AA1,ITGAV,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NCF2,NF1,KSR2,PAK3,PDGFRA,PDPK1,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKCB,PRKCZ,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,MAPK12,RASA3,CNKSR2,ELMO2,SPTAN1,SPTB,MLST8,TEK,UBC,VAV1,VAV2,RICTOR" Pathway 1268814 GABA A receptor activation BioSystems: REACTOME 6.11E-05 1.88E-01 2.42E-03 2.09E-02 9 13 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,ARHGEF9" Pathway 1268767 Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels BioSystems: REACTOME 6.11E-05 1.88E-01 2.42E-03 2.09E-02 9 13 "CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNA2D2,CACNG2,CACFD1" Pathway 1222951 Renin secretion BioSystems: KEGG 6.14E-05 1.89E-01 2.42E-03 2.09E-02 25 65 "ADCY5,ADCY6,ADCYAP1R1,ADORA1,ADRB2,AGT,CACNA1D,CALM1,EDNRA,GNAS,GUCY1A2,GUCY1A1,GUCY1B1,KCNMA1,PDE1A,PDE1C,PDE3A,PDE3B,PDE1B,PLCB2,PPP3CA,PPP3CB,PPP3CC,PRKACB,PLCB1" Pathway 83072 Gap junction BioSystems: KEGG 6.28E-05 1.93E-01 2.45E-03 2.11E-02 31 88 "ADCY2,ADCY5,ADCY6,ADCY8,DRD1,EGFR,TUBA1B,TUBB3,TUBB4A,TUBA8,GNAS,TUBA1C,GRM1,GRM5,GUCY1A2,GUCY1A1,GUCY1B1,HTR2A,TUBB2B,PDGFRA,PLCB2,PRKACB,PRKCB,PRKCG,MAPK3,MAPK7,PLCB1,TJP1,TUBB2A,TUBB1,TUBA1A" Pathway 1269445 p75 NTR receptor-mediated signalling BioSystems: REACTOME 6.48E-05 2.00E-01 2.50E-03 2.15E-02 34 100 "ABR,PLEKHG5,FGD2,ARHGDIA,ARHGEF7,KALRN,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF10,ARHGEF4,TIAM2,APH1A,LINGO1,MAG,OMG,MAPK8,RASGRF2,ARHGEF10L,ITSN1,ARHGEF40,FGD4,ARHGEF9,MCF2L,ARHGEF12,ITGB3BP,TIAM1,TRIO,UBC,VAV1,VAV2,RTN4" Pathway 1269483 VEGFA-VEGFR2 Pathway BioSystems: REACTOME 6.85E-05 2.11E-01 2.61E-03 2.24E-02 87 333 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,WASF1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CDC42,NRG2,CSF2RA,CTNND1,CYBB,ELMO1,DLG4,ABI1,DUSP9,RASGRP1,EGFR,ABI2,RASA4,ERBB2,ERBB4,PTK2B,FGF1,FGFR1,FGFR3,BAIAP2,WDR83,NRG3,FYN,AHCYL1,NCKAP1,WASF3,GFRA1,GFRA2,GRIN1,GRIN2C,GRIN2D,NCKAP1L,HSP90AA1,ITGAV,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NCF2,NF1,KSR2,PAK3,PDGFRA,PDPK1,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKCB,PRKCZ,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,MAPK12,RASA3,CNKSR2,ELMO2,SPTAN1,SPTB,MLST8,TEK,UBC,VAV1,VAV2,RICTOR" Pathway 1268830 Voltage gated Potassium channels BioSystems: REACTOME 7.44E-05 2.29E-01 2.80E-03 2.41E-02 19 44 "KCNH8,KCNAB2,KCNAB3,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNQ2,KCNQ3,KCNAB1" Pathway M5940 "Endocytotic role of NDK, Phosphins and Dynamin" MSigDB C2 BIOCARTA (v6.0) 9.87E-05 3.04E-01 3.66E-03 3.15E-02 11 19 "AP2A1,AMPH,BIN1,SYNJ1,SYNJ2,CALM1,DNM1,EPN1,PPP3CA,PPP3CB,PPP3CC" Pathway M11650 Nitric Oxide Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.04E-04 3.19E-01 3.80E-03 3.27E-02 12 22 "CALM1,DLG4,GRIN1,GRIN2C,GRIN2D,NOS1,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKAR1B,PRKCB" Pathway 154409 Gastric acid secretion BioSystems: KEGG 1.20E-04 3.70E-01 4.36E-03 3.75E-02 27 75 "ADCY2,ADCY5,ADCY6,ADCY8,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CCKBR,GNAS,MYLK2,KCNJ10,KCNJ16,KCNK2,KCNK10,PLCB2,PRKACB,PRKCB,PRKCG,SST,SSTR2,PLCB1" Pathway 1270314 Netrin-1 signaling BioSystems: REACTOME 1.29E-04 3.97E-01 4.62E-03 3.98E-02 18 42 "UNC5A,CDC42,SLIT2,DCC,AGAP2,ABLIM2,FYN,PTK2,ROBO1,ABLIM3,SLIT1,UNC5B,UNC5D,RGMB,TRIO,TRPC1,TRPC3,RGMA" Pathway 217716 Cholinergic synapse BioSystems: KEGG 1.49E-04 4.59E-01 5.27E-03 4.54E-02 36 112 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,CACNA1A,CACNA1B,CACNA1D,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CHRM1,CHRM4,CHRNA4,CHRNB2,CREB5,FYN,GNAO1,GNG3,GNG4,JAK2,KCNJ3,KCNJ4,KCNQ2,KCNQ3,GNG2,PIK3CD,PIK3R1,PLCB2,PRKACB,PRKCB,PRKCG,MAPK3,PLCB1,PIK3R5" Pathway 1268801 CREB phosphorylation through the activation of Ras BioSystems: REACTOME 1.56E-04 4.80E-01 5.45E-03 4.69E-02 14 29 "ACTN2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D,PDPK1,RASGRF1,RASGRF2,RPS6KA2" Pathway 1268805 CREB phosphorylation through the activation of CaMKII BioSystems: REACTOME 1.73E-04 5.34E-01 6.00E-03 5.16E-02 10 17 "ACTN2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D" Pathway 1269883 Lysosome Vesicle Biogenesis BioSystems: REACTOME 1.82E-04 5.59E-01 6.19E-03 5.33E-02 16 36 "AP1B1,APP,ARRB1,AP1M1,AP4M1,CLTA,CLTB,CLTC,DNAJC6,DNM2,CLVS1,AP4B1,AP4S1,CLVS2,SH3GL2,AP4E1" Pathway 1270329 NrCAM interactions BioSystems: REACTOME 1.85E-04 5.69E-01 6.19E-03 5.33E-02 6 7 "ANK1,NRP2,DLG3,DLG4,NRCAM,CNTN2" Pathway 1339118 Phase 1 - inactivation of fast Na+ channels BioSystems: REACTOME 1.85E-04 5.69E-01 6.19E-03 5.33E-02 6 7 "KCND1,KCND2,KCND3,KCNIP3,KCNIP2,KCNIP1" Pathway 1269380 Signaling by EGFR BioSystems: REACTOME 2.14E-04 6.60E-01 7.10E-03 6.11E-02 92 367 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,ARHGEF7,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,CDC42,EPS15L1,NRG2,CSF2RA,LRIG1,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,PIK3AP1,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,EPN1,MAPKAP1,SH3KBP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,SH3GL2,SH3GL3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC2,UBC,VAV1,RICTOR" Pathway 153376 Salivary secretion BioSystems: KEGG 2.54E-04 7.81E-01 7.85E-03 6.76E-02 30 90 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2B1,ATP2B2,ATP2B3,CALM1,CD38,CST3,GNAS,GUCY1A2,GUCY1A1,GUCY1B1,KCNMA1,NOS1,PLCB2,PRKACB,PRKCB,PRKCG,RYR3,SLC12A2,PLCB1" Pathway SMP00326 Fosphenytoin (Antiarrhythmic) Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00328 Lidocaine (Antiarrhythmic) Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway 1268800 Post NMDA receptor activation events BioSystems: REACTOME 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ACTN2,ADCY8,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D,PDPK1,PRKACB,RASGRF1,RASGRF2,RPS6KA2" Pathway SMP00331 Flecainide Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00323 Quinidine Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00332 Ibutilide Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00329 Mexiletine Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00325 Disopyramide Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00327 Phenytoin (Antiarrhythmic) Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00330 Tocainide Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway SMP00324 Procainamide (Antiarrhythmic) Pathway SMPDB 2.68E-04 8.24E-01 7.85E-03 6.76E-02 16 37 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,CACNA2D2,ABCC9,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK1,SLC8A1,ABCC8" Pathway 1427859 Cargo recognition for clathrin-mediated endocytosis BioSystems: REACTOME 3.03E-04 9.33E-01 8.76E-03 7.54E-02 32 99 "ADRB2,AP2A1,AP2A2,ARRB1,ARRB2,REPS2,EPS15L1,CLTA,CLTB,CLTC,COPS7A,KIAA0319,SNAP91,EGFR,COPS4,SGIP1,COPS8,STON1,AGFG1,SYT9,EPN1,SH3KBP1,ITSN1,SH3GL2,SH3GL3,EPN2,FCHO1,SYT11,SYT1,TACR1,TF,UBC" Pathway M15181 Regulation of PGC-1a MSigDB C2 BIOCARTA (v6.0) 3.05E-04 9.41E-01 8.76E-03 7.54E-02 12 24 "CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PPARGC1A,MEF2C,PPARA,PPP3CA,PPP3CB,PPP3CC,CAMK1G" Pathway 83085 Long-term potentiation BioSystems: KEGG 3.07E-04 9.46E-01 8.76E-03 7.54E-02 24 67 "ADCY8,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,GRIA1,GRIA2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,PLCB2,PPP1R1A,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,RPS6KA2,PLCB1" Pathway 1383059 SALM protein interactions at the synapses BioSystems: REACTOME 3.25E-04 1.00E+00 9.19E-03 7.91E-02 11 21 "LRFN2,LRFN1,DLG3,DLG4,RTN3,GRIA1,GRIA4,GRIN1,GRIN2C,GRIN2D,PTPRD" Pathway 83053 Neuroactive ligand-receptor interaction BioSystems: KEGG 3.69E-04 1.00E+00 1.03E-02 8.90E-02 72 278 "ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,CCKBR,P2RX6,CHRM1,CHRM4,CHRNA4,CHRNB2,CNR1,GRIN3A,DRD1,EDNRA,EDNRB,LPAR6,CALCRL,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GALR1,GHR,GLRB,PRLHR,LPAR4,MCHR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,HTR2A,HTR5A,P2RY13,OPRL1,OXTR,P2RX7,P2RY1,PTAFR,PTH1R,SSTR1,SSTR2,TACR1,THRA,PARD3,NTSR2,VIPR2" Pathway 83048 MAPK signaling pathway BioSystems: KEGG 3.78E-04 1.00E+00 1.05E-02 9.04E-02 67 255 "TAOK1,MAP4K3,ARRB1,ARRB2,PLA2G4C,FGF17,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CDC25B,CDC42,CACNA2D2,TAOK2,MAP4K4,DUSP9,RASGRP1,CACNG7,EGFR,RASGRP2,ECSIT,CACNG3,CACNG2,TAOK3,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,FLNC,PTPN5,HSPA1L,STMN1,MAPT,MEF2C,NF1,NTRK2,PDGFRA,PPM1B,PPP3CA,PPP3CB,PPP3CC,PPP5C,PRKACB,PRKCB,PRKCG,MAPK3,MAPK7,MAPK8,MAPK9,MAPK10,RASGRF1,RASGRF2,RPS6KA2,MAPK12,MRAS,TAB2,MAPK8IP3,MAP3K12" Pathway 1270231 Cell-Cell communication BioSystems: REACTOME 3.83E-04 1.00E+00 1.05E-02 9.06E-02 40 134 "ACTN1,ACTN2,DSCAML1,CASK,CADM3,DST,CLDN10,CDH2,CDH8,CDH10,CDH18,ARHGEF6,NECTIN3,CTNND1,SIRPA,DCC,MAGI2,PARD6A,DSCAM,SIRPB1,PTK2B,FLNC,FYB1,FYN,KIRREL3,FERMT2,LIMS1,AFDN,CLDN11,PIK3R1,PLEC,MAPK8,PTK2,KIRREL1,MAPK12,LIMS2,SPTAN1,PARD3,CADM1,CADM2" Pathway 1269145 Neurotoxicity of clostridium toxins BioSystems: REACTOME 3.96E-04 1.00E+00 1.07E-02 9.22E-02 7 10 "SV2B,SV2A,STX1B,SNAP25,STX1A,VAMP1,SYT1" Pathway M477 Gamma-aminobutyric Acid Receptor Life Cycle MSigDB C2 BIOCARTA (v6.0) 3.96E-04 1.00E+00 1.07E-02 9.22E-02 7 10 "DNM1,GPHN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5" Pathway 1270102 Regulation of insulin secretion BioSystems: REACTOME 4.05E-04 1.00E+00 1.08E-02 9.26E-02 27 80 "ADCY5,ADCY6,ADCY8,CACNA1A,CACNA1D,CACNA1E,CACNB2,CACNA2D2,AKAP5,AHCYL1,GNAS,GNG3,GNG4,RAPGEF4,KCNB1,KCNC2,KCNJ11,GNG2,PLCB2,PRKACB,PRKAR1B,SNAP25,STX1A,STXBP1,ABCC8,PLCB1,SYT5" Pathway 546258 Cocaine addiction BioSystems: KEGG 4.05E-04 1.00E+00 1.08E-02 9.26E-02 19 49 "ADCY5,RGS9,CDK5R1,CREB5,GPSM1,DLG4,GRIN3A,DRD1,PPP1R1B,GNAS,GRIA2,GRIN1,GRIN2C,GRIN2D,GRM2,GRM3,MAOB,PDYN,PRKACB" Pathway P00003 Alzheimer disease-amyloid secretase pathway PantherDB 4.98E-04 1.00E+00 1.30E-02 1.12E-01 23 65 "APBA2,APBB1,APP,CACNA1D,CACNB2,CHRM1,CHRM4,APOPT1,KLC1,PCSK1,PCSK2,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,KLC2" Pathway 138070 Regulation of RhoA activity BioSystems: Pathway Interaction Database 5.02E-04 1.00E+00 1.30E-02 1.12E-01 18 46 "ABR,ARHGAP5,ARHGDIA,ARHGDIG,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF10,DLC1,OPHN1,ARHGEF10L,MCF2L,ARHGEF12,ARHGAP9,TRIO,VAV1,VAV2" Pathway 83094 Type II diabetes mellitus BioSystems: KEGG 5.02E-04 1.00E+00 1.30E-02 1.12E-01 18 46 "CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,GCK,KCNJ11,PIK3CD,PIK3R1,PKM,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,HKDC1,ABCC8,SOCS4" Pathway 1268808 Activation of Kainate Receptors upon glutamate binding BioSystems: REACTOME 5.57E-04 1.00E+00 1.43E-02 1.23E-01 14 32 "CALM1,DLG3,DLG4,NCALD,GNG3,GNG4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GNG2,PLCB2,PLCB1" Pathway 1269563 Nucleotide-like (purinergic) receptors BioSystems: REACTOME 5.85E-04 1.00E+00 1.48E-02 1.28E-01 9 16 "ADORA1,ADORA2A,ADORA3,LPAR6,GPR17,LPAR4,P2RY13,P2RY1,P2RY12" Pathway 983748 cGMP-PKG signaling pathway BioSystems: KEGG 5.87E-04 1.00E+00 1.48E-02 1.28E-01 46 163 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA3,ADRA1D,ADRA1B,ADRB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1D,CALM1,CREB5,EDNRA,EDNRB,KCNMB2,MRVI1,KCNMB4,GUCY1A2,GUCY1A1,GUCY1B1,MYLK2,KCNMA1,MEF2C,MYH7,NPR2,PDE2A,PDE3A,PDE3B,PLCB2,PPP3CA,PPP3CB,PPP3CC,MAPK3,SLC8A2,SLC8A1,SLC8A3,PLCB1,PIK3R5" Pathway 121494 Dilated cardiomyopathy BioSystems: KEGG 6.03E-04 1.00E+00 1.51E-02 1.30E-01 29 90 "ADCY2,ADCY5,ADCY6,ADCY8,ATP2A2,CACNA1D,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,DMD,CACNG7,CACNG3,CACNG2,GNAS,IGF1,ITGA7,ITGAV,LAMA2,MYH6,MYH7,MYL3,PRKACB,SLC8A1,TPM1,TPM2,TPM3,TPM4" Pathway 1269284 DAP12 signaling BioSystems: REACTOME 6.34E-04 1.00E+00 1.58E-02 1.36E-01 88 359 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,BTK,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,KLRC2,PIK3AP1,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,TREM2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC2,UBC,VAV1,VAV2,RICTOR" Pathway 1311074 Phospholipase D signaling pathway BioSystems: KEGG 6.50E-04 1.00E+00 1.60E-02 1.38E-01 42 146 "ADCY2,ADCY5,ADCY6,ADCY8,DGKZ,DGKD,PLA2G4C,DGKI,DGKB,DGKG,DNM1,DNM2,EGFR,LPAR6,PTK2B,FYN,GAB1,GNAS,LPAR4,RAPGEF4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KIT,SHC3,KITLG,PDGFRA,PIK3CD,PIK3R1,PLCB2,MAPK3,RALGDS,MRAS,SHC4,PLCB1,PIK3R5,TSC1,TSC2,SPHK2" Pathway 1270324 Recycling pathway of L1 BioSystems: REACTOME 6.59E-04 1.00E+00 1.61E-02 1.39E-01 13 29 "AP2A1,AP2A2,SHTN1,NUMB,CLTA,CLTC,DNM1,DNM2,DPYSL2,L1CAM,RDX,RPS6KA2,SH3GL2" Pathway 1269988 Inositol phosphate metabolism BioSystems: REACTOME 6.80E-04 1.00E+00 1.65E-02 1.42E-01 18 47 "SYNJ1,CALM1,PLCH2,IP6K1,IP6K2,IP6K3,PLCD4,INPP1,INPP5B,ITPKA,ITPKB,OCRL,PLCB2,PLCD1,NUDT11,NUDT10,PLCB1,PLD4" Pathway 83099 Amyotrophic lateral sclerosis (ALS) BioSystems: KEGG 7.27E-04 1.00E+00 1.75E-02 1.51E-01 19 51 "APAF1,ALS2,BID,TOMM40L,GRIA1,GRIA2,GRIN1,GRIN2C,GRIN2D,NEFM,NEFH,NOS1,PPP3CA,PPP3CB,PPP3CC,PRPH,MAPK12,SLC1A2,TNFRSF1B" Pathway 1269953 Stimuli-sensing channels BioSystems: REACTOME 7.98E-04 1.00E+00 1.90E-02 1.64E-01 32 104 "TTYH1,ASIC2,ASIC1,UNC79,ASPH,CALM1,ASIC3,CLCN3,CLCN4,SGK2,SLC9B2,TTYH2,BEST3,NALCN,RYR1,RYR3,SCNN1D,ASIC4,SGK1,UNC80,ANO4,TPCN2,TRPC1,TRPC3,TRPM2,ANO5,SGK3,UBC,BEST1,WNK1,WNK3,WNK2" Pathway 1268721 Sialic acid metabolism BioSystems: REACTOME 8.11E-04 1.00E+00 1.92E-02 1.65E-01 14 33 "ST3GAL5,GNE,ST8SIA3,ST3GAL6,ST6GALNAC3,NEU3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,NEU4,NPL,ST8SIA2" Pathway 1270267 Ligand-independent caspase activation via DCC BioSystems: REACTOME 9.23E-04 1.00E+00 2.17E-02 1.87E-01 7 11 "UNC5A,MAGED1,APPL1,DAPK1,DAPK3,DCC,UNC5B" Pathway 1270313 NCAM1 interactions BioSystems: REACTOME 9.43E-04 1.00E+00 2.20E-02 1.89E-01 15 37 "CACNA1I,CACNA1G,CACNA1D,CACNB2,CACNB4,COL4A5,COL9A1,COL9A2,COL9A3,NCAN,GFRA1,GFRA2,NCAM1,CNTN2,ST8SIA2" Pathway 1270302 Developmental Biology BioSystems: REACTOME 9.81E-04 1.00E+00 2.27E-02 1.96E-01 230 1081 "ACTN2,BRAP,UNC5A,AP2A1,AP2A2,SEMA6A,ALCAM,ANK1,ANK2,ANK3,SEMA7A,PKP4,CNTNAP1,SHTN1,SPTBN4,ARRB1,ARRB2,NCOA1,NUMB,ADAM23,FGF17,NRP2,KSR1,CDK5R1,ARHGEF7,CACNA1I,CACNA1G,CACNA1D,CACNB2,CACNB4,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SPAG9,CDC42,CDH2,LGI1,SLIT2,KMT2C,CLTA,CLTB,CLTC,NGEF,CNTN1,COL4A5,COL9A1,COL9A2,COL9A3,NRG2,CRMP1,NCOR1,NCOR2,CSF2RA,NCAN,PLXNA4,BOC,DCC,MED24,SRGAP3,DLG3,DLG4,DNM1,MED12,CDON,DNM2,DPYSL2,DUSP9,EBF1,RASGRP1,EFNA2,EFNA3,EFNB3,APH1A,EGFR,PLXNC1,RASA4,EPHA5,EPHB1,ERBB2,ERBB4,CACNG3,CACNG2,FGF1,FGFR1,FGFR3,CAP2,AGAP2,FOXO3,EVL,SEMA4D,WDR83,DPYSL4,NRG3,ABLIM2,FYN,GAB1,CHL1,FAM120B,GAP43,GCK,GDF1,GFRA1,GFRA2,PPARGC1A,RND1,ZNF638,GRB10,GRIN1,GRIN2C,GRIN2D,HNF4G,HSP90AA1,RBPJ,INSM1,ITGAV,JAK1,JAK2,KCNQ2,KCNQ3,KIT,L1CAM,MARK3,ADAM11,SHC3,MEF2C,MEIS1,KITLG,GIT1,ADAM22,NCAM1,NEUROD1,NF1,NKX2-2,NODAL,NRCAM,KSR2,TREM2,PAK3,PAX6,PBX1,PDGFRA,PIK3CD,PIK3R1,PLIN1,PLXNB1,PLXNB3,POLR2F,PPARA,MED1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,MAPK3,MAPK7,PSMA6,LAMA1,PSMD13,PTK2,RAP1GAP,RASGRF1,RASGRF2,RDX,RET,LGI2,MYH14,ROBO1,ROBO2,EPHA10,RPS6KA2,RXRA,STX1B,SALL1,MAPK12,SEMA6D,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCN8A,RASA3,ITSN1,SH3GL2,CHD9,CNKSR2,ABLIM3,LGI3,SLIT1,SMARCD3,SCN3B,SOX2,DOK5,UNC5B,SPTAN1,SPTB,CDK19,NFASC,CLASP2,STX1A,KAZN,SEMA4A,ROBO3,UNC5D,CNTN2,TBL1X,TCF4,TCF12,CLASP1,ARHGEF12,HIF3A,TEK,LEFTY2,TIAM1,DOK6,RGMB,TRIO,TRPC1,TRPC3,UBC,VAV2,LGI4,ZIC3,DPYSL5,RGMA,PAK5,ST8SIA2" Pathway 1270304 Semaphorin interactions BioSystems: REACTOME 1.02E-03 1.00E+00 2.35E-02 2.02E-01 23 68 "SEMA6A,SEMA7A,CDK5R1,CDC42,CRMP1,PLXNA4,DPYSL2,PLXNC1,ERBB2,SEMA4D,DPYSL4,FYN,RND1,HSP90AA1,TREM2,PAK3,PLXNB1,PLXNB3,MYH14,SEMA6D,SEMA4A,ARHGEF12,DPYSL5" Pathway 83052 Phosphatidylinositol signaling system BioSystems: KEGG 1.04E-03 1.00E+00 2.35E-02 2.03E-01 30 97 "DGKZ,DGKD,SYNJ1,SYNJ2,MTMR3,MTMR2,CALM1,MTMR7,DGKI,DGKB,DGKG,IP6K1,IP6K2,IP6K3,INPP5K,PLCD4,INPP1,INPP5B,ITPKA,ITPKB,OCRL,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PRKCB,PRKCG,PLCB1,MTMR14" Pathway 1269347 Reduction of cytosolic Ca++ levels BioSystems: REACTOME 1.05E-03 1.00E+00 2.35E-02 2.03E-01 8 14 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,SLC8A2,SLC8A1,SLC8A3" Pathway 1269478 Signaling by PDGF BioSystems: REACTOME 1.05E-03 1.00E+00 2.35E-02 2.03E-01 91 379 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,COL4A5,COL9A1,COL9A2,COL9A3,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,RAPGEF1,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,PIK3AP1,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPP1,SPTAN1,SPTB,MLST8,TEK,THBS4,TSC2,UBC,VAV1,RICTOR" Pathway 1270312 NCAM signaling for neurite out-growth BioSystems: REACTOME 1.13E-03 1.00E+00 2.52E-02 2.17E-01 70 279 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CACNA1I,CACNA1G,CACNA1D,CACNB2,CACNB4,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,COL4A5,COL9A1,COL9A2,COL9A3,NRG2,CSF2RA,NCAN,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,WDR83,NRG3,FYN,GFRA1,GFRA2,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,PDGFRA,PPP2R5C,PPP2R5E,PPP5C,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,CNTN2,TEK,UBC,ST8SIA2" Pathway 138013 Internalization of ErbB1 BioSystems: Pathway Interaction Database 1.16E-03 1.00E+00 2.56E-02 2.21E-01 14 34 "AMPH,ZFYVE28,SYNJ1,ARHGEF7,CDC42,LRIG1,DNM1,EGFR,STAMBP,PIK3R1,EPN1,SH3KBP1,ITSN1,SH3GL2" Pathway 1269584 Opioid Signalling BioSystems: REACTOME 1.17E-03 1.00E+00 2.57E-02 2.21E-01 27 85 "ADCY2,ADCY5,ADCY6,ADCY8,CALM1,PPP1R1B,AHCYL1,GNAL,GNAO1,GNG3,GNG4,PDE1A,PDE1C,PDE4A,PDE4B,PDE4D,PDE1B,PDYN,GNG2,PLCB2,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKAR1B,PRKCG,PLCB1" Pathway 1268784 Neurotransmitter uptake and Metabolism In Glial Cells BioSystems: REACTOME 1.26E-03 1.00E+00 2.70E-02 2.33E-01 4 4 "GLUL,SLC1A2,SLC1A3,SLC38A1" Pathway 1270319 Regulation of Commissural axon pathfinding by Slit and Robo BioSystems: REACTOME 1.26E-03 1.00E+00 2.70E-02 2.33E-01 4 4 "SLIT2,ROBO1,ROBO2,ROBO3" Pathway 1268785 Astrocytic Glutamate-Glutamine Uptake And Metabolism BioSystems: REACTOME 1.26E-03 1.00E+00 2.70E-02 2.33E-01 4 4 "GLUL,SLC1A2,SLC1A3,SLC38A1" Pathway P05730 Endogenous cannabinoid signaling PantherDB 1.37E-03 1.00E+00 2.90E-02 2.50E-01 11 24 "CACNA1G,CACNA1A,CACNA1B,CNR1,GNAO1,GNG3,GNG4,GRM1,GRM5,PLCB2,PLCB1" Pathway P00041 Metabotropic glutamate receptor group I pathway PantherDB 1.37E-03 1.00E+00 2.90E-02 2.50E-01 11 24 "GRIN3A,GRIK1,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,PRKACB,PRKAR1B,PRKCB" Pathway 1269592 Gastrin-CREB signalling pathway via PKC and MAPK BioSystems: REACTOME 1.38E-03 1.00E+00 2.92E-02 2.52E-01 104 446 "ABHD6,ACTN2,BRAP,ADRA1D,ADRA1B,AGT,DGKZ,DGKD,APP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF25,CCK,CCKBR,DGKI,CHRM1,NRG2,CSF2RA,DGKB,DGKG,DLG4,DUSP9,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,EGFR,RASA4,LPAR6,RASGRP2,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,WDR83,NRG3,FYN,GFRA1,GFRA2,GNG3,GNG4,GPR17,LPAR4,MCHR1,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,HTR2A,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,OXTR,P2RY1,PDGFRA,GNG2,PIK3R1,PLCB2,PPP2R5C,PPP2R5E,PPP5C,MAPK3,MAPK7,PSMA6,PSMD13,PTAFR,PTK2,RASGRF1,RASGRF2,RET,RGS3,RPS6KA2,RASA3,CNKSR2,SPTAN1,SPTB,PLCB1,TAC1,TAC3,TACR1,TEK,TRH,TRIO,TRPC3,NTSR2,UBC" Pathway 1268824 Inwardly rectifying K+ channels BioSystems: REACTOME 1.41E-03 1.00E+00 2.96E-02 2.54E-01 13 31 "ABCC9,GABBR1,GNG3,GNG4,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,GNG2,ABCC8" Pathway 83071 Tight junction BioSystems: KEGG 1.54E-03 1.00E+00 3.21E-02 2.76E-01 46 170 "ACTN1,MYH7B,MPDZ,CACNA1D,CLDN10,ARHGEF2,CDC42,MAGI1,JAM2,MYL6B,TJP2,PARD6A,DLG2,DLG3,ERBB2,TUBA1B,AMOTL2,PRKAG2,RAPGEF6,IGSF5,TUBA8,TUBA1C,BVES,SYNPO,TJAP1,AFDN,MYH3,CLDN11,EPB41L4B,PPP2R2B,PPP2R2C,PRKAB2,PRKACB,PRKCZ,MAPK8,MAPK9,MAPK10,RDX,MYH14,MYH15,TIAM1,TJP1,PARD3,AMOT,TUBA1A,ACTR3B" Pathway 1269283 DAP12 interactions BioSystems: REACTOME 1.58E-03 1.00E+00 3.26E-02 2.80E-01 89 374 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,BTK,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,SIRPB1,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,KLRC2,PIK3AP1,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,TREM2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC2,UBC,VAV1,VAV2,RICTOR" Pathway 1268822 Ca2+ activated K+ channels BioSystems: REACTOME 1.59E-03 1.00E+00 3.26E-02 2.80E-01 6 9 "KCNMB2,KCNMB4,KCNMA1,KCNN1,KCNN2,KCNN3" Pathway 1269479 Downstream signal transduction BioSystems: REACTOME 1.64E-03 1.00E+00 3.35E-02 2.88E-01 85 355 "ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,TNRC6C,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CD86,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GAB1,AHCYL1,GFRA1,GFRA2,TNRC6A,RAPGEF1,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,PIK3AP1,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,PDE1A,PDE1C,PDE1B,PDGFRA,PDPK1,PIK3CD,PIK3R1,MAPKAP1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,PRKAR1B,PRKCG,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC2,UBC,VAV1,RICTOR" Pathway 1269989 Synthesis of IP3 and IP4 in the cytosol BioSystems: REACTOME 1.71E-03 1.00E+00 3.44E-02 2.96E-01 12 28 "SYNJ1,CALM1,PLCH2,PLCD4,INPP5B,ITPKA,ITPKB,OCRL,PLCB2,PLCD1,PLCB1,PLD4" Pathway 1269873 RORA activates gene expression BioSystems: REACTOME 1.71E-03 1.00E+00 3.44E-02 2.96E-01 12 28 "ARNTL,NCOA1,CLOCK,NCOR1,PPARGC1A,PPARA,MED1,RXRA,CHD9,SMARCD3,TBL1X,SIRT1" Pathway 1269501 MAPK family signaling cascades BioSystems: REACTOME 1.76E-03 1.00E+00 3.51E-02 3.03E-01 72 293 "ACTN2,BRAP,TNRC6C,CDC14B,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SEPT7,CDC42,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,FOXO3,WDR83,NRG3,FYN,GFRA1,GFRA2,TNRC6A,GRIN1,GRIN2C,GRIN2D,IL6R,IL6ST,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,MOV10,NCAM1,NF1,KSR2,PAK3,PDGFRA,PPP2R5C,PPP2R5E,PPP5C,PRKACB,MAPK3,MAPK4,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,TEK,UBC,XPO1" Pathway 1269344 cGMP effects BioSystems: REACTOME 1.77E-03 1.00E+00 3.51E-02 3.03E-01 9 18 "KCNMB2,MRVI1,KCNMB4,KCNMA1,PDE1A,PDE2A,PDE3A,PDE3B,PDE1B" Pathway 102279 Endocytosis BioSystems: KEGG 1.83E-03 1.00E+00 3.61E-02 3.11E-01 65 260 "ADRB2,AP2A1,AP2A2,SNX32,AMPH,BIN1,ARRB1,ARRB2,CDC42,EPS15L1,ZFYVE9,CLTA,CLTB,CLTC,CSF1R,ZFYVE16,IST1,GIT2,DNAJC6,PARD6A,DNM1,DNM2,PDCD6IP,SH3GLB1,EGFR,ERBB4,FGFR3,AGAP2,AGAP3,FLT1,PSD2,FOLR2,STAMBP,ARFGAP2,WASHC2A,GRK4,HSPA1L,SMAP1,KIF5A,KIF5C,KIT,ZFYVE27,GIT1,PDGFRA,EPN1,SH3KBP1,PRKCZ,PSD,RAB5B,IQSEC3,RET,SH3GL2,SH3GL3,ASAP3,EPN2,ARFGAP1,IQSEC2,SPART,WASHC4,PSD3,PARD3,WIPF1,SH3GLB2,WIPF2,MVB12B" Pathway 1269613 WNT5A-dependent internalization of FZD4 BioSystems: REACTOME 1.90E-03 1.00E+00 3.72E-02 3.20E-01 8 15 "AP2A1,AP2A2,ARRB2,CLTA,CLTB,CLTC,PRKCB,PRKCG" Pathway 83063 Hedgehog signaling pathway BioSystems: KEGG 1.98E-03 1.00E+00 3.87E-02 3.33E-01 17 47 "SPOP,ARRB1,ARRB2,PTCH2,BTRC,CSNK1E,CSNK1G3,BOC,CDON,GLI2,KIF3A,PRKACB,PTCH1,KIF7,FBXW11,GPR161,HHIP" Pathway P00029 Huntington disease PantherDB 2.16E-03 1.00E+00 4.18E-02 3.60E-01 35 123 "AP2A1,AP2A2,APAF1,VAT1L,DYNLL1,KALRN,HAP1,CAPN3,CDC42,CLTB,NCOR1,NCOR2,DCTN1,DLG4,GRIN3A,DYNC1I1,TUBB3,TUBB4A,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,TUBB2B,PACSIN1,MAPK9,PRODH,SH3GL3,SIN3B,DNAH7,TUBB2A,TUBB1" Pathway P05731 GABA-B receptor II signaling PantherDB 2.22E-03 1.00E+00 4.27E-02 3.68E-01 14 36 "ADCY2,ADCY5,ADCY6,ADCY8,CACNA1G,CACNA1A,CACNA1B,GABBR1,GNAO1,GNG3,GNG4,KCNJ3,PRKACB,PRKAR1B" Pathway 948277 Inflammatory mediator regulation of TRP channels BioSystems: KEGG 2.24E-03 1.00E+00 4.28E-02 3.68E-01 29 97 "ASIC2,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,PLA2G6,PLA2G4C,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ASIC3,GNAS,HTR2A,IGF1,PIK3CD,PIK3R1,PLCB2,PRKACB,PRKCB,PRKCG,MAPK8,MAPK9,MAPK10,MAPK12,ASIC4,PLCB1" Pathway 1269429 Insulin receptor signalling cascade BioSystems: REACTOME 2.37E-03 1.00E+00 4.48E-02 3.86E-01 73 301 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,EIF4G1,ERBB2,ERBB4,RRAGB,STRADA,FGF1,FGFR1,FGFR3,PRKAG2,WDR83,NRG3,FYN,GAB1,CAB39,GFRA1,GFRA2,GRB10,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,PDE3B,PDGFRA,PDPK1,PIK3R1,PPP2R5C,PPP2R5E,PPP5C,PRKAB2,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC1,TSC2,UBC,CAB39L" Pathway 1268815 GABA B receptor activation BioSystems: REACTOME 2.39E-03 1.00E+00 4.48E-02 3.86E-01 15 40 "ADCY2,ADCY5,ADCY6,ADCY8,GABBR1,GNAL,GNG3,GNG4,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,GNG2" Pathway 1268816 Activation of GABAB receptors BioSystems: REACTOME 2.39E-03 1.00E+00 4.48E-02 3.86E-01 15 40 "ADCY2,ADCY5,ADCY6,ADCY8,GABBR1,GNAL,GNG3,GNG4,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,GNG2" Pathway 1427866 RET signaling BioSystems: REACTOME 2.57E-03 1.00E+00 4.79E-02 4.13E-01 67 273 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,ERBB2,ERBB4,FGF1,FGFR1,FGFR3,WDR83,NRG3,FYN,GAB1,GFRA1,GFRA2,GRB10,GRIN1,GRIN2C,GRIN2D,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,PDGFRA,PIK3CD,PIK3R1,PPP2R5C,PPP2R5E,PPP5C,PRKACB,MAPK3,MAPK7,PSMA6,PSMD13,PTK2,RAP1GAP,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,DOK5,SPTAN1,SPTB,TEK,DOK6,UBC" Pathway 1269620 IRS-related events triggered by IGF1R BioSystems: REACTOME 2.60E-03 1.00E+00 4.79E-02 4.13E-01 73 302 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,EIF4G1,ERBB2,ERBB4,RRAGB,STRADA,FGF1,FGFR1,FGFR3,PRKAG2,WDR83,NRG3,FYN,GAB1,CAB39,GFRA1,GFRA2,GRIN1,GRIN2C,GRIN2D,IGF1,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,PDE3B,PDGFRA,PDPK1,PIK3R1,PPP2R5C,PPP2R5E,PPP5C,PRKAB2,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC1,TSC2,UBC,CAB39L" Pathway 1269618 IGF1R signaling cascade BioSystems: REACTOME 2.60E-03 1.00E+00 4.79E-02 4.13E-01 73 302 "ACTN2,BRAP,SPTBN4,ARRB1,ARRB2,FGF17,KSR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,NRG2,CSF2RA,DLG4,DUSP9,RASGRP1,EGFR,RASA4,EIF4G1,ERBB2,ERBB4,RRAGB,STRADA,FGF1,FGFR1,FGFR3,PRKAG2,WDR83,NRG3,FYN,GAB1,CAB39,GFRA1,GFRA2,GRIN1,GRIN2C,GRIN2D,IGF1,JAK1,JAK2,KIT,MARK3,SHC3,KITLG,NCAM1,NF1,KSR2,PDE3B,PDGFRA,PDPK1,PIK3R1,PPP2R5C,PPP2R5E,PPP5C,PRKAB2,MAPK3,PSMA6,PSMD13,PTK2,RASGRF1,RASGRF2,RET,RASA3,CNKSR2,SPTAN1,SPTB,MLST8,TEK,TSC1,TSC2,UBC,CAB39L" Pathway 1270328 Neurofascin interactions BioSystems: REACTOME 2.67E-03 1.00E+00 4.89E-02 4.21E-01 5 7 "ANK1,CNTNAP1,CNTN1,NRCAM,NFASC" Pubmed 28671696 Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Pubmed 4.37E-148 1.00E-142 1.00E-142 1.30E-141 381 916 "ABR,ASIC1,TMEM132B,ADD1,SLC12A5,AP2A1,AP2A2,AP1B1,GPR158,CASKIN1,KCTD16,LRRC7,UNC79,KCNT1,BEGAIN,AMPD2,BIN1,LRFN1,OGT,LRCH2,ANK3,USP28,PPFIA1,PKP4,CNTNAP1,KCNAB2,APC,DGKZ,PPFIA3,SHTN1,CASK,SPTBN4,ZSCAN18,CCAR2,DYNLL1,SLC4A4,DOCK11,ADGRB2,ADGRB3,MPDZ,HCN2,SYNJ1,ARHGEF7,BSN,WASF1,CACNA1A,CACNA1E,CACNA2D1,CACNB2,CACNB4,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,SHISA7,LDB2,INA,DGKI,ARHGEF2,SEPT7,CDH2,CDH10,DCLK1,LRRFIP1,LGI1,MAGI1,DLGAP2,DLGAP1,NUMBL,RAB3C,TAOK2,DLGAP3,EPS15L1,NRXN1,CLU,CLTC,NGEF,MAP4K4,NIPBL,HOMER3,CNTN1,ARMC8,SLC4A8,MAGED1,CNRIP1,CDC42BPB,PREPL,AKAP12,CRMP1,NCOR1,NCOR2,GDA,RGS6,SEC24C,OSBPL3,SIPA1L1,NCAN,PDE4DIP,DZIP3,ERC2,APPL1,CTNND1,CTNND2,PPP6R2,GPRASP1,ARHGAP32,TCAF1,ARHGAP24,HDAC4,TBC1D5,MATR3,DAPK1,DAPK3,GIT2,SIRPA,DBN1,ARMCX4,DNAJC6,DCTN1,JAKMIP2,ZEB2,MYEF2,KIAA0319,CEP170,MAGI2,PLPPR4,SNAP91,SRGAP3,G3BP2,SEC16A,DLG2,DLG3,DLG4,EXOG,DNM1,DNM2,SHANK1,DPYSL2,ABI1,PDCD6IP,DSCAM,DYRK1A,FARSB,DNM1L,EEF1A2,FRY,ABI2,EIF4G1,ELAVL2,ELAVL3,ELAVL4,EML1,EPB41L1,EPB41L2,MTSS1L,GPHN,APC2,CACNG2,RACK1,BAIAP2,CAMSAP1,FOXG1,CAP2,AGAP2,RGPD5,ANKFY1,SGIP1,NOP56,SYT3,DPYSL4,NBEA,SORBS1,SMC2,FAM49B,ADGRA1,BRSK1,NEURL4,NCKAP1,IQGAP2,GLUL,GNAO1,GOLGB1,PRRC2B,GPM6A,RAPGEF4,TPPP,GRIA1,GRIA2,DIDO1,GRIA4,GRIK2,GRIK3,GRIK5,GRIN1,GRIN2D,GRM1,GRM2,GRM3,GRM5,CIT,GSN,KIF3A,SYNPO,HNRNPK,HSP90AA1,DOCK7,TJAP1,TMEM240,TUBB2B,LRRTM1,KCNA1,KCNA2,KCNA4,KCNB1,KCNJ4,KCNJ10,KCNJ16,KCNMA1,KIF2A,KIF5A,KIF5C,KLC1,MAP6,AFDN,MPP2,GIT1,JAKMIP3,ADAM22,TAGLN3,MYO5A,HNRNPM,NCAM1,RCOR2,NEFH,CCDC13,NF1,NOS1,NRCAM,HCN1,NTRK2,KSR2,NUMA1,OPA1,P2RX7,PAK3,PCDH8,PDE2A,PDE4A,PDE4B,PDE1B,NLGN3,SSH1,CAMKV,PLCL1,JAKMIP1,PLP1,STRN3,SH3KBP1,PPP3CA,PPP3CB,PRKACB,PRKAR1B,PRKCB,PRKCG,MAPK3,PROX1,PTK2,PTPRN2,FAM120C,PEX5,RAB3A,IQSEC3,RDX,KIF7,PBRM1,RPS6KA2,CLIP1,RTN1,SBF1,ATXN2,TRIM46,CASC3,SFPQ,TRA2B,KIF21A,ITSN1,PPP1R9A,SH3GL2,CNKSR2,SEC31A,ABLIM3,SLC1A2,SLC1A3,FAM81A,RPH3A,WDR47,CCDC88A,TRIM67,SHANK2,ATF7IP,SPHKAP,SMARCA4,SMARCC2,CDK5RAP2,LIMCH1,RIMS1,TRERF1,TNIK,KIF21B,HECW1,UHRF1BP1L,MYCBP2,ERC1,SPTAN1,IQSEC2,DDN,NFASC,SRPK2,CLASP2,EPB41L3,ERBIN,NCDN,MAPK8IP3,MPRIP,SEPT3,KLHL7,ZC3H4,PRRC2C,SYNE2,DNAJC9,PLCB1,SYN1,ARC,SYT1,ANKRD28,MTCL1,CAMSAP2,TBL1X,SMG6,SIN3B,DMXL2,ZEB1,CLASP1,WDR7,SYNE1,NSD1,ARHGEF12,SIK3,TJP1,ICAM5,RIMBP2,PARD3,CABIN1,TNR,TNS1,TP53BP1,TP53BP2,TPD52L2,LRRC24,TRIO,TSC1,TSC2,TTC3,HIRA,UBE3A,VGF,CLIP2,ZIC2,ANKS1B,EMSY,STOX2,PPP1R3F,KCNAB1,WNK3,WNK2,PAK5,FXR1,NETO1,SPATA13" Pubmed 24952961 A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Pubmed 1.29E-135 2.97E-130 1.49E-130 1.92E-129 543 1835 "CPNE2,TTYH1,SERPINA3,ABAT,ASIC2,ASIC1,ACHE,ADCY2,DSCAML1,ADCYAP1R1,AXIN2,FZD9,ADORA2A,UNC5A,MTA3,PCDH19,AGT,NR0B1,SEMA6A,ALCAM,PCDH10,ALK,TRMT9B,AMH,ANK3,SEMA7A,APBA2,APC,APLP1,VAT1L,APP,AQP4,SEMA4G,SPTBN4,ARNTL,ASCL1,NCOA1,NUMB,ASTN1,ALDH4A1,ATP1A1,ATP1A2,B3GALT2,CADM3,BACH1,BCHE,FGF17,CFLAR,PROM1,BMP7,BMPR1B,CDK5R1,JAZF1,CACNA1G,BAIAP3,BTRC,FOXK1,CACNA1A,CACNA1B,DDR1,CACNA2D1,CALB1,CALB2,HAP1,CAMK2A,RUNX1T1,ARHGEF25,CCK,LDB2,CCKBR,CERS5,SCARB1,CDH2,KCNAB3,CDH8,CDH10,CDH18,LARGE1,ZNF445,IGFN1,NOG,CRLF1,GPR37L1,ADGRG1,CHRM1,CHRM4,SYNPR,CHRNA4,CHRNB2,SLIT2,LHX2,KMT2C,NRXN1,CLU,NGEF,FAM189A2,VAX2,CNR1,CNTN1,WHRN,COL4A5,COL9A1,LETMD1,COL9A3,COL11A2,MAGED1,AHCTF1,NRG2,NECTIN3,CLOCK,SLC32A1,C1QL2,NCOR1,NCOR2,GDA,CRYM,AATK,CSF1,CSF1R,FEZ1,CSNK1E,CST3,PLXNA4,CTNND1,ST18,PYGO1,BOC,TOX,MAML1,DBI,DCC,ZEB2,TIAM2,BLOC1S6,LYPD1,NTM,ARNT2,DLG4,DLX1,GRIN3A,HS3ST4,OLIG1,MED12,SLC29A4,NR1D2,CDON,DRD1,E2F5,E2F6,EBF1,EDNRB,HEYL,SEMA3D,CACNG7,EFNA2,EFNA3,EFNB3,CELSR3,APH1A,EGFR,PLXNC1,EMX2,EN2,OLIG2,EPHA5,EPHB1,ERBB2,ERBB4,CDHR1,APC2,ETV1,ADGRV1,NRN1,ZIC4,TUBB3,EFEMP1,PPP1R1B,FGF1,FGF12,FGF14,FGFR1,FGFR3,SCARA3,FOXG1,FOXM1,SEMA6C,FOXO3,EVL,SEMA4D,FLT1,SORBS1,DACH2,DLL3,ADGRA1,TBR1,NRG3,FYN,DKK3,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,CHL1,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,NKX6-2,GALR1,NCKAP1,GAP43,DISC1,DNER,IGSF5,GBX2,GDF1,MSTN,GDF9,GFAP,GFRA1,GFRA2,CSDC2,PPARGC1A,NTNG2,GLRB,GLS,TOX3,GLUL,PCDH11X,KCNMB4,MCHR1,GPR26,GPR37,GRK4,PCLO,RAPGEF4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,PRDM5,GRM5,GRM8,CIT,KAT7,WIF1,MAEL,TOX2,ZHX1,HRH3,BACH2,HLF,HMX1,HNF4G,TLX1,HTR2A,HTR5A,SOWAHA,IGF1,IGFBP1,NKD1,ZIC5,RBPJ,HES5,IL6ST,INPP1,LRRTM1,ITGAM,ITGAV,KCNA1,KCNA2,CDH20,KCNC1,KCNC2,KCND2,KCNK2,KCNQ3,KIF5C,KIT,L1CAM,LIFR,LIMS1,LMO1,SMAD1,SMAD9,MAOB,MAP2,MAPT,MBP,MEF2C,MEIS2,MEST,KITLG,MITF,MOBP,MOG,SCG3,RSPO2,MDGA1,MYBPC1,MYCN,LAYN,MYT1,FXYD6,NCAM1,NCAM2,RCOR2,NEFH,NEUROD1,NF1,NFIA,NFE2L2,NFIX,NFYA,NHLH1,NKX2-2,NNAT,NODAL,NOS1,NPY,NRCAM,HCN1,NTRK2,NTRK3,DDR2,GPR88,CLDN11,OXTR,P2RX7,PAH,CNTN3,PAX6,PCSK2,PDE1A,PDE1C,PDGFRA,PDYN,PENK,SEMA5B,PIK3R1,PKD1,NLE1,PLCD1,PLP1,PCDH18,PLXNB1,PLXNB3,PRRX1,NECAB2,FAT3,POU3F2,POU3F4,POU6F1,IRX1,PPARA,LRRN3,PPP3CA,PRKCB,MAPK8,MAPK9,MAPK10,PRODH,PROX1,RELN,PSD,LAMA1,PTCH1,PTHLH,PTK2,PTPRZ1,QDPR,RAB3A,RASGRF1,RASGRF2,DBX2,FEZF2,CRTAC1,ZMAT4,RET,RGS4,RGS10,PBRM1,ZFHX4,LGI2,ROBO1,ROBO2,RORB,EPHA10,FBXW7,LRRK2,SOX8,KCNIP2,RXRA,RXRG,S100B,SEMA6D,SATB1,ATXN1,DRAXIN,SCN4B,SOX6,SGK1,SCG5,ITSN1,ARX,NTNG1,FNDC3A,BCAN,CLSTN1,SLC1A2,SLC1A3,SLC1A6,SLC6A1,PKNOX2,SLC6A11,SLC12A2,LGI3,SLIT1,CXXC4,ABTB1,SMARCE1,SNCA,PDZD2,MYT1L,SOX2,SOX5,SOX10,SOX11,ZHX3,MYCBP2,SPP1,UNC5B,PEG10,NPAS3,NFASC,SRPK2,CLSTN2,CAMTA2,POGZ,SST,SSTR1,SSTR2,LRRC4,MAPK8IP3,STX1A,VAMP1,SYN1,ARC,SYT1,ASTN2,TAC1,TAC3,TACR1,SEMA4A,ROBO3,CAMTA1,TAF6,TAF9,TAL1,UNC5D,CNTN2,TBX15,TCF4,SATB2,CUX2,TCF7L2,ZEB1,TCF12,NSD1,AKNA,PCDHA7,HIF3A,TEK,TF,ZFPM2,LEFTY2,GPR161,TGFBR3,HHIP,THRA,TIAM1,TIE1,HEY1,ICAM5,NR2E1,HEY2,DAAM2,PARD3,TNNT1,NR2C2,TRH,TRPS1,NTSR2,TSC1,TSC2,CADM1,RPRM,UBE3A,UBTF,MGAT5B,VAV2,VGF,VIPR2,NSD2,PORCN,PCDH20,ZIC1,ZIC2,ZIC3,ZNF24,ZBTB16,ZNF189,DPYSL5,LAMP5,MEIS3,CA10,LRP8,EVI5,SCG2,SEMA3B,SLC17A7,KCNAB1,SLC17A6,FZD3,ST7,PHTF2,CBLN2" Pubmed 17114649 Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Pubmed 6.58E-105 1.51E-99 5.04E-100 6.51E-99 190 330 "SYN3,GPRIN1,XKR4,ELFN2,ADCY5,ADD1,ADD2,ADD3,AP2A1,CASKIN1,TAOK1,LRRC7,BEGAIN,BIN1,PPFIA2,PKP4,CNTNAP1,APC,BCAS1,MADD,ATP1A1,ATP1A2,EIF4G3,STX16,ATP2A2,ATP2B2,ATP6V0A1,ADGRB3,HCN2,SYNJ1,ARHGEF7,BSN,CACNA1A,CACNA1B,CACNA1E,CACNB4,CAMK2A,CAMK2B,CAMK2G,CANX,BRSK2,ARHGEF2,SEPT7,DCLK1,DLGAP1,NUMBL,GPR37L1,EPS15L1,NGEF,NRG2,SIPA1L1,PITPNM3,ERC2,CTNND1,CTNND2,RIMS2,PPP6R2,RIMS3,TOMM20,DBN1,DNAJC6,RUSC2,C2CD2L,MAGI2,SNAP91,SV2A,SRGAP3,G3BP2,KBTBD11,DLG2,DLG4,DPYSL2,ABI1,EPB41L1,DMTN,RTN3,CACNG3,ATP8A1,BAIAP2,CAP2,AGAP2,SGIP1,NBEA,SORBS1,SPECC1,CAMKK2,ABLIM2,GABBR1,GABRA1,GABRA3,GAP43,GNG3,GPM6B,TMEM121B,PCLO,GRIN1,GRM7,CIT,ATXN2L,SYNPO,SLC6A17,KCNA2,KCNA4,KCNB1,KCND2,KCNMA1,KCNQ2,STXBP5,L1CAM,STMN1,MAP2,MAP4,MAPT,MPP2,GIT1,ADAM22,SAMD14,MYO5A,NCAM1,NCAM2,NEFH,NF1,NRCAM,HCN1,CLDN11,PALM,PDPK1,GNG2,PIK3C2A,PLEC,SH3KBP1,PPP3CA,PRKACB,PRKCB,PRKCG,MAPK10,BCAS3,SYTL2,PTK2,TMEM145,RAB3A,IQSEC3,OXR1,RASGRF1,RGS7,RTN1,AMER2,HSPA4L,ITSN1,CPEB3,MYO18A,CNKSR2,BCAN,CCDC92,ABLIM3,SLC1A2,SLC1A3,EPN2,RADIL,SHANK2,ARFGAP1,RIMS1,MYCBP2,TEX2,SPTAN1,EPB41L3,MAPK8IP3,STXBP1,PLCB1,SYN1,SYN2,ADGRL3,DMXL2,WDR7,DOCK9,PHF24,AHCYL2,RIMBP2,MTCH1,TOM1L2,CLIP2,FMN2,NDRG4,DHX33,SLC30A3,TMEM163,ITM2C,RTN4,SLC4A10,JPH3" Pubmed 28611215 Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Pubmed 1.13E-93 2.60E-88 6.50E-89 8.40E-88 416 1489 "RALGAPA1,ABAT,KCNH8,ABR,ARID1A,PLEKHH1,SNX30,ESYT2,LRFN2,KIDINS220,MTA3,ZNF608,INTS2,GPR158,TBC1D14,PLA2G6,LRRC7,SEMA6A,ALCAM,TRMT9B,PITPNM2,OGT,CDC42BPA,ANK3,PPFIA2,ANXA7,APBB2,TNRC6C,APP,SHTN1,SHROOM2,CDC14B,SFMBT2,PPP4R4,PDXK,CASK,SPTBN4,ARRB1,ARRB2,CDK13,ASPH,NUMB,EIF4G3,ATP2B1,SLC2A11,KIF1A,BARD1,BMPR1B,SYNJ2,FUBP1,BAIAP3,DDR1,CACNB2,PTBP2,CAMK2B,CAST,CBFA2T2,SCARB1,LRBA,ZMYM4,EVI5L,MAGI1,NUMBL,CACNA2D2,ADGRG1,SRSF11,FOXN3,CASC2,KMT2C,EPS15L1,RPL32P3,RAB28,NGEF,FAM19A5,HECTD1,FAM149A,COL4A5,BTF3L4,MYRIP,CHD1L,ZNF385A,CDC42BPB,C2CD2,RBM39,SH2B1,ANKRD44,NCOR2,ABCG1,MICAL2,RASGEF1C,SDC3,PHF14,GREB1,ARHGEF4,CTNND1,DCAF8,HDAC4,TM9SF4,TBC1D5,CTIF,PLEKHM1,HP1BP3,CEP170,ZC3H11A,SMG7,SGSM2,USP3,RPS6KL1,TRAPPC9,SLC12A6,DPP6,DPYSL2,PDCD6IP,DTNA,DTNB,TOM1,SNX29,EEF1A2,SGK2,HIPK3,FAM13A,SUGP2,EGFR,MBNL2,TNK2,BSCL2,PAN3,HSD17B14,VPS13B,EPB41,EPB41L1,ERBB2,ETV1,RTN3,ANKMY1,KATNAL1,ADGRV1,NSRP1,ZNF461,SH3YL1,ZNF589,FECH,KIAA1109,FGF13,BAIAP2,PRKAG2,POLK,SCARA3,UBE2E3,CAP2,AGAP3,FOXO3,EVL,SEMA4D,FOLH1,POMT1,ATP2C1,NRG3,MPP6,ABLIM2,ZNF512,ZMAT1,STAG2,ZNF44,NEK6,TMEM8B,SEPT9,STARD10,WASF3,SESN1,AHDC1,MALT1,SPIN1,GLI2,GLYR1,TOX3,ZNF638,OS9,LUZP2,DCLK2,RAB40B,GNAS,GNG4,GPT2,GOLGB1,PRUNE2,ATF7,FUT10,GRB10,PARD3B,GRIK1,GRIK2,RNF165,BVES,GUCY1A1,HPS5,MAN1B1,FRMD3,SYNPO,IGF1,KNDC1,TJAP1,IL6R,ZNF385B,ITPKB,JAK2,KCND3,KCNJ3,KLHL23,KCNMA1,KCNN2,KIF5C,LSS,PACRG,MAP2,MAP4,MAPT,MARK3,MBNL1,MBP,MDM4,MKLN1,AFF1,MMP16,MRPL42,STK32C,MSRA,MYO5A,MYO6,MYO9A,MYT1,NCAM2,NFIA,NFIX,KSR2,NUCB2,OGDH,OPRL1,GPR137C,ZNF827,PAK3,PBX1,PDE3B,PDE4D,PFKFB4,CDK14,NLGN3,PSAT1,SPATA6,EPB41L4B,POLG,PPARA,TATDN3,PPP2R2C,PPP3CA,VSTM2L,PRKACB,PRKAR1B,PRKCZ,NDUFS7,BCAS3,VPS13C,SLC22A23,WDR25,PTK2,PTPN13,PTPRB,PTPRE,PTPRG,PTPRN2,FAM120C,C1orf109,RIPOR1,MARCH1,RAD52,ZNF793,HKR1,ZDHHC14,SLC25A36,RIC8B,ZNF532,SETD5,MYH14,KIAA0895L,SGSM1,RPS6KA2,ATAT1,KCNIP3,YJEFN3,KCNIP2,RXRA,ZNF331,ATXN1,ATXN2,ATXN7,SCP2,FNIP1,TNFRSF19,CASC3,GALNT10,RASA3,SCAF8,NLGN4Y,SH3BGR,SH3BP2,PPP1R9A,FRMPD1,MAGI3,CHD9,SLITRK3,ST3GAL3,WDR37,NBPF1,KANSL3,PKNOX2,SHANK2,EFHD1,NAXD,MAST1,RCOR3,TTC17,IFT122,IGSF9B,LIMCH1,RIMS1,MBD5,TMCC1,KDM4B,DOP1A,PDZD2,BDP1,FNBP1,NMNAT2,MYCBP2,SPTB,KIF1B,CDK19,TSPYL2,NFASC,LHPP,SRPK2,CLASP2,ZC4H2,LARP4,SSPO,ERBIN,ST5,NCDN,INKA2,MAPK8IP3,PHLDB1,FAM168A,ABCC8,ARHGEF9,COBL,ASTN2,ATP11A,ANKRD12,CAMTA1,MCF2L,FBXW11,TBL1X,SMG6,MGRN1,ATMIN,EHBP1,TCF7L2,TPCN2,PCDHGB1,FRYL,AHCYL2,THRA,NACC2,TJP1,ANKRD24,CSMD1,PARD3,KAT6B,RBFOX2,TRIO,TRPM2,TRPS1,TMPRSS5,TTTY15,TTC3,TMEFF2,UBE2H,SLC35A4,VAV2,BEST1,LMF1,NSD2,PORCN,ZNF708,ZBTB16,ZNF189,DPYSL5,SPIRE1,MEIS3,INTS3,SLC30A4,MAP3K12,LRP8,CSDE1,VPS35L,SEMA3B,CAB39L,WNK2,ST7,KAT6A,HNRNPA3,TMEM63C,CERS6,JMJD1C,ZNF248,NETO1" Pubmed 12693553 Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.38E-86 3.18E-81 6.36E-82 8.22E-81 190 395 "RBM10,SLC25A25,CSMD3,KLHL32,ADCY2,ADCY6,RNF157,SLC12A5,PLEKHH1,GRAMD1B,USP31,UNC5A,LRFN2,KIDINS220,KLHL13,PCDH19,LRRC7,MARCH4,PCDH10,LRCH2,EP400,ALS2,VAT1L,LRRC4C,TNRC6C,MADD,IGDCC4,CADPS,MARK4,BRINP2,CCAR2,DCAF5,MTMR3,BAIAP3,CAMK2A,LARGE1,CLTC,WHRN,TENM4,SEC24C,SIPA1L1,PDE4DIP,DZIP3,ERC2,ARHGEF4,PUM1,ST18,RUBCN,DOCK4,RIPOR2,SNPH,FRMPD4,KIAA0513,ZFYVE16,RIMS3,IST1,DGKB,SPOCK2,SPATA2,DNAJC6,ZEB2,MFAP3L,RUSC2,C2CD2L,KIAA0319,MAGI2,ZC3H11A,SV2B,SV2A,SRGAP3,SGSM2,RABGAP1L,SEC16A,DLG3,FEM1B,SUGP2,VPS13B,EPB41L1,SPEG,CHST15,ANKFY1,SORBS1,CAMKK2,MEGF11,NCKAP1,SEPT9,WASHC2A,USP19,KIRREL3,PRRC2B,GRB10,NEGR1,DOCK7,DISP2,STXBP5,MARK3,NEFH,NRCAM,OPA1,PLXNB3,PPP2R5E,KANSL1,GON4L,RIPOR1,IQSEC3,ZYG11B,LGI2,SETD5,SEMA6D,FNIP1,SCAF8,PPP1R9A,PPM1E,FRMPD1,DOCK10,R3HDM2,CNKSR2,NLGN1,ZNF365,DHX30,WDR47,BTBD7,SPHKAP,SLIT1,MAST1,LIMCH1,MAPKBP1,FAIM2,USP33,SON,PDZD2,TNIK,FNBP1,ZHX3,ERC1,ZNF423,KIF1B,CDK19,ZBTB43,RAP1GAP2,DDN,CAMTA2,POGZ,ERBIN,NCDN,PHLDB1,KANK1,GANAB,GSE1,FAM168A,SYT11,MLC1,JMJD6,PRRC2C,ZFR2,ARHGEF9,COBL,ANKRD12,MTCL1,CAMTA1,MCF2L,CAMSAP2,ADGRL3,KIAA1107,AGTPBP1,ATMIN,ACSL6,CLASP1,WDR7,SYNE1,DOCK9,PHF24,PSD3,ARHGEF12,PUM2,AHCYL2,DAAM2,RIMBP2,R3HDM1,SEZ6L,TRO,TSC1,FSTL5,SMARCAD1,CSDE1,NAV3,SNX27,NUP214,SPATA13,SENP7" Pubmed 27507650 Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Pubmed 1.05E-73 2.41E-68 4.01E-69 5.18E-68 136 241 "ABR,TMEM132B,CASKIN1,LRRC7,BEGAIN,ANK3,CNTNAP1,KCNAB2,DGKZ,SPTBN4,ADGRB2,ADGRB3,MPDZ,SYNJ1,ARHGEF7,WASF1,CACNB2,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,INA,SEPT7,DCLK1,LGI1,DLGAP2,DLGAP1,RAB3C,TAOK2,DLGAP3,NRXN1,CLU,HOMER3,CNTN1,CNRIP1,GDA,NCAN,ERC2,CTNND1,CTNND2,ARHGAP32,SIRPA,DNAJC6,DCTN1,DLG2,DLG3,DLG4,DNM1,SHANK1,DPYSL2,ABI1,EPB41L1,EPB41L2,CACNG2,RACK1,BAIAP2,AGAP2,NBEA,SORBS1,ADGRA1,NCKAP1,IQGAP2,GLUL,GNAO1,GPM6A,RAPGEF4,TPPP,GRIA1,GRIA2,GRIA4,GRIK2,GRIK5,GRIN1,GRIN2D,GRM3,GRM5,CIT,GSN,SYNPO,TUBB2B,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ10,KCNJ16,KIF5C,MPP2,GIT1,ADAM22,MYO5A,NCAM1,NEFH,HCN1,PDE2A,PDE4B,NLGN3,PLCL1,SH3KBP1,PPP3CA,PPP3CB,PRKACB,PRKCB,PRKCG,MAPK3,PTK2,RAB3A,IQSEC3,RPS6KA2,PPP1R9A,CNKSR2,SLC1A2,SLC1A3,FAM81A,SHANK2,TNIK,SPTAN1,IQSEC2,DDN,NFASC,EPB41L3,ERBIN,NCDN,MPRIP,SEPT3,PLCB1,SYN1,ARC,SYT1,DMXL2,SYNE1,TRIO,ANKS1B,KCNAB1,NETO1" Pubmed 28706196 Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. Pubmed 1.63E-72 3.75E-67 5.35E-68 6.92E-67 140 259 "RALGAPA1,ACTN1,GPRIN1,AP2A1,AP2A2,AP1B1,KCTD16,LRRC7,BEGAIN,PITPNM2,AMPH,ANK3,PPFIA2,PPFIA1,PKP4,CNTNAP1,KCNAB2,DGKZ,ADGRB2,SYNJ1,WASF1,CACNA1E,CACNB2,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SHISA7,INA,SEPT7,CDH10,DCLK1,DLGAP2,DLGAP1,NUMBL,RAB3C,DLGAP3,CLTC,CNRIP1,CRMP1,GDA,SIPA1L1,NCAN,APPL1,CTNND2,RIMS2,ARHGAP32,DBN1,SRGAP3,AK5,KBTBD11,DLG2,DLG3,DLG4,DNM1,DYNC1I1,SHANK1,DPYSL2,DNM1L,EPB41L1,EPB41L2,GPHN,CACNG2,PTK2B,BAIAP2,AGAP2,NBEA,SORBS1,CAMKK2,NCKAP1,IQGAP2,GLUL,GNAO1,GNAS,PCLO,RAPGEF4,GRIA1,GRIA2,GRIN1,GRIN2D,GRM1,GRM2,GRM3,GRM5,CIT,GSN,SYNPO,SHISA6,ITPKA,KCNA4,KCNJ10,MAP6,GIT1,ADAM22,MYO5A,NCAM1,NCAM2,NF1,NRCAM,NTRK3,OPA1,NLGN3,PLCL1,PPP3CA,PPP3CB,PRKACB,PRKCB,PRKCG,PKN2,MAPK3,MAPK10,PTK2,RAB3A,IQSEC3,PPP1R9A,PPM1E,CNKSR2,NLGN1,SLC1A3,FAM81A,SHANK2,RIMS1,TNIK,SPTAN1,IQSEC2,DDN,EPB41L3,NCDN,STXBP1,ARC,DMXL2,WDR7,SYNE1,SIK3,TNR,TP53BP2,PRMT8,TRIO,ANKS1B" Pubmed 24154525 Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Pubmed 2.49E-70 5.72E-65 7.14E-66 9.23E-65 161 348 "CPNE2,ABAT,ADARB2,SEMA6A,ALCAM,DPP10,ANK1,CPNE5,AQP4,SEMA4G,IGDCC4,CADPS,ASCL1,ATP1A2,C1QC,CALB2,SYT6,VSTM2A,PRC1,CBS,ENTPD2,CD81,KCNAB3,CACNA2D2,GPR37L1,ADGRG1,PLEKHB1,RAB3C,LHX2,CLU,QKI,CNN3,CNR1,COL9A3,HAPLN1,SLC32A1,CNTNAP2,CST3,NRSN1,RIMS3,DBI,ZNF804A,ELMO1,ARNT2,DLX1,EGFR,ELAVL2,RCAN2,MTSS1L,SEZ6,EPS8,ERBB4,ADGRV1,FABP7,ST3GAL6,FGF12,FGFR1,CSPG5,ADGRA1,MEGF10,GAA,GAD1,GAD2,GAP43,ACSS1,CPLX1,DNER,GFAP,GLDC,GLRB,GLUL,GNAS,STMN2,GRIA4,GRIK1,CIT,PTPRT,GSN,GYG1,PADI2,IGFBPL1,IRF8,IGF1,HES5,KCNC1,KCNC2,KCNK1,KIT,STMN1,LSAMP,MBP,TM6SF1,MOBP,MOG,MSI1,SCG3,MYBPC1,MYCN,FXYD6,NEFH,NEUROD1,NFIA,NNAT,NOS1,NPY,HCN1,NTRK2,CLDN11,PDE3A,SLC10A4,SERPINE2,SERPINI1,PLP1,PLTP,PSAT1,NECAB2,SEPT4,NXPH1,RASGEF1B,RELN,PTHLH,PTN,PTPRN,PTPRZ1,PTX3,FEZF2,RGS10,RGS12,LGI2,ROBO1,PLPPR3,ATAT1,WLS,ST6GAL1,BCAN,SLC1A2,SLC1A3,SLC6A1,SLC8A1,SLC14A1,MYO16,SOX2,SOX11,ACSBG1,MLC1,TAC1,TAC3,KAZN,CUX2,THBS4,NACC2,DAAM2,HSPBP1,HEPACAM,VAV2,DPYSL5,LAMP5,CAMK1G,NETO1,CBLN2,SPATA13" Pubmed 15226823 Genomic analysis of mouse retinal development. Pubmed 3.50E-66 8.05E-61 8.94E-62 1.16E-60 279 961 "TTYH1,ADAR,GRAMD1B,FZD9,MTUS1,SORCS2,SPARCL1,C1QTNF4,FAM135A,PITPNM2,BIN1,LCORL,APC,DDO,SEMA4G,PDXK,CADPS,NCOA1,CCAR2,TTC9B,BBS2,RGS9,BMP7,CDK5R1,BSN,CDK5R2,FOXK1,DDR1,CACNB2,CAMK2D,BRSK2,LDB2,USP2,C1orf52,CD81,DCLK1,ZMYM4,LARGE1,COPB2,ADGRG1,CHGA,CHGB,CHRM1,TAOK2,SLIT2,LHX2,NRXN2,CLU,CLTB,TMEM59L,BTF3L4,LETMD1,ZNF385A,RBM39,CRHBP,SLC32A1,NCOR1,NCOR2,CLIP3,CRYM,PDE4DIP,FAM169A,PITPNM3,GREB1,PUM1,MED24,SV2B,SRGAP3,RABGAP1L,KBTBD11,DLG4,DMTF1,FAM57B,ABI1,DTNA,EBF1,SEZ6L2,PHC2,FEM1B,MBNL2,EIF5,TMEM35A,EML1,EPB41,EPB41L2,SEZ6,GPHN,ERCC2,NCALD,CDHR1,EZH1,FABP7,TUBA1B,PRMT5,KIAA1109,FGFR1,FGFR3,IP6K2,EVL,ANKFY1,NOP56,DPYSL4,TACC2,ARFGAP2,OGA,PHYHIPL,DKK3,GABBR1,GABRB3,SALL3,STARD10,CPLX2,CPLX1,WASHC2A,CYP46A1,GLDC,GLYR1,GLUL,CBX1,PCSK1N,GNAO1,PRRC2B,EML4,GPR37,GRB10,RFFL,COQ10A,CELF3,IGSF21,TOX2,ACOT7,TCEAL6,HSP90AA1,BTBD17,SHISAL1,NKD1,RBPJ,NIM1K,HES5,ZNF385B,KCNK1,KCNQ3,KIF5C,KIT,TTYH2,STMN1,SMAD1,NAT8L,MAN2A2,MAP2,MARK3,MAT2A,MBNL1,MEST,KITLG,SCAMP5,MPP2,COMMD5,PTOV1,SAMD14,MYCN,RCOR2,NEUROD1,NHLH1,NNAT,CNOT4,NPY,LRIT2,PCBP3,PAK3,PAX6,PDGFRA,DUSP26,SERPINI1,NOMO2,PIK3R1,PKD1,KCTD15,PLEC,PMS2,PRRX1,SEPT4,POLR2F,DIRAS2,LRRC49,DEF8,SNRK,PTK2,NKAIN1,RALGDS,RAP1GDS1,SLC6A15,ZMAT4,RNASEL,ZFHX4,CARF,ROBO1,RORB,ELP2,PCMTD2,RPL15,ATAT1,RTN1,SATB1,SCP2,HES6,ZNF821,RASA3,SGK1,SCG5,HKDC1,CLSTN1,SLC1A7,PPP4R3A,SLC6A1,SLC6A9,SLC6A11,SEPHS1,RAB3GAP1,CDK5RAP3,NAPB,SPHKAP,LGI3,SLIT1,EPC1,ZKSCAN3,MAST1,SNAP25,SNCB,USP33,SOX2,SPATA7,SOX11,ZSWIM8,SRPK2,ERBIN,ELOVL4,STX1A,STXBP1,ZC3H4,SYT1,TAC1,MMS19,ROBO3,MCF2L,TMEM136,SIN3B,TCF7L2,TCF12,USP22,PSD3,NSD1,FRYL,TMPO,PIK3R5,TPD52,SMUG1,TSC1,CADM1,FAM155A,USP1,PLPPR2,VIPR2,WNT7A,NPDC1,ZIC3,ZNF24,ZFP41,NDRG4,ZNF184,LAMP5,ZFAND5,LRP8,GDPD5,PRDM8,SCG2,NAV3,SLC17A7,FZD3" Pubmed 11544199 Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Pubmed 6.89E-52 1.58E-46 1.58E-47 2.05E-46 252 947 "KLHL32,INTS2,TAOK1,FAM135A,MRTFA,ANK3,PPFIA1,APC,DGKZ,ALS2,SHROOM2,MIER1,MADD,TMEFF1,ARHGAP5,ZBTB10,DDX3Y,ATP2B1,DCAF5,SYNJ1,BAIAP3,CACNB2,PTBP2,CAMK2D,ARHGEF1,ENTPD6,CDC27,DCLK1,ZNF445,COPB2,CNOT8,KMT2C,PLAA,CLTC,FBXO7,TJP2,ARHGEF6,ARMC8,AKAP6,COL4A5,SLC4A7,AHCTF1,FAM171B,AKAP12,CRMP1,SEC24C,FEZ2,CSNK1E,OSBPL3,CSNK1G3,ATRNL1,SIPA1L1,VCAN,SOCS5,DZIP3,KIAA0040,PUM1,MYADM,GAPVD1,TCAF1,RIPOR2,MATR3,SPOCK2,DCTN1,ZBTB24,TIAM2,KIAA0753,COPS7A,MED24,ZC3H11A,ALKBH8,SEC16A,DNM2,DMTF1,PDCD6IP,DYRK1A,FARSB,DNM1L,FEM1B,KLHL5,EIF4G2,IRAK4,PAN3,VPS13B,LRRC17,SLC43A2,MRPL10,RPS6KC1,TAOK3,RACK1,FECH,KIAA1109,POLK,SUCO,NOP56,FLYWCH1,TACC2,DOT1L,ZMAT1,STAG2,HBS1L,RAPGEF6,SALL3,IQGAP2,GCNT2,ARFIP1,WASHC2A,PPARGC1A,BRD8,SPIN1,GLYR1,ZNF638,FERMT2,GOLGB1,CNTRL,DIDO1,ZNF496,KAT7,AP4S1,FAM107A,PACSIN2,MAN1B1,NCKAP1L,KLF12,HNRNPK,ICA1,IFI16,RBPJ,DIPK1A,KCNH1,KCNJ3,KIF2A,LIMS1,PAXBP1,MAP4,MAP6,MARK1,MBNL1,MEST,MKLN1,AFF1,DBNL,NASP,NEUROD1,ALDH1L2,NRDC,P2RX7,PDE4B,NLGN3,ANLN,PIK3CD,PIK3R1,ZNF655,CCSER2,FAM216A,PLEC,PCDH18,SMIM7,PLXNB1,C11orf49,EXOSC10,PMS2,EPB41L4B,FA2H,POLG,PPP2R5E,PRKCZ,EPDR1,DEF8,PTCH1,ANKHD1,UHRF1BP1,PTPN13,EML5,RAD17,SETD5,RPL15,PRR5L,LGR4,WLS,ZNF821,SFPQ,ITSN1,SH3GL3,FRMPD1,SHMT2,FBXO11,ST6GAL1,SEC31A,ANKRD6,ABLIM3,SLC1A3,SMTN,CDK5RAP3,TET1,ARFGAP1,OGDHL,CDK5RAP2,KIF13A,LMBRD1,MYT1L,FNBP1,CAND2,UHRF1BP1L,TEX2,ARHGAP26,TAB2,CLASP2,CAMTA2,ERBIN,NCDN,SEPT8,TTBK2,FAM168A,SYT1,ATP11A,ANKRD12,PJA1,CAMTA1,FAM208A,TCEA1,DOCK9,NSD1,CRTC1,FRYL,CHST8,SLC44A1,CBX5,DDHD1,PARD3,TP53BP1,TRH,STXBP4,TTC3,TUB,UBC,AMOT,UBTF,TOM1L2,CLDND1,RICTOR,ZNF24,ZNF32,FMN2,SPIRE1,TFIP11,WNK1,PRDM2,VPS35L,SNX27,PHTF2,FXR1" Pubmed 16169070 A human protein-protein interaction network: a resource for annotating the proteome. Pubmed 1.14E-50 2.61E-45 2.37E-46 3.07E-45 363 1678 "DPF1,ABCF1,RBM10,ACTN2,KIDINS220,AP2A1,DISP3,CEP126,BBOX1,BIN1,LRFN1,PKP4,APLP1,DGKZ,DGKD,FAM131A,ARHGDIA,ARRB2,ARSE,CADPS,MARK4,DYNLL1,ATP1A1,ALDH7A1,NOL4,ADGRB2,BCS1L,ARHGEF7,FUBP1,NAE1,SGCE,IL33,CA8,CA12,DDR1,CACNB4,HAP1,TRIM41,CANX,CBR1,AIFM1,CD81,CDK11B,CDC42,CDH10,MAGI1,TBRG4,CHGB,CHN1,CHN2,MS4A7,CPNE6,NRXN2,CLTB,CLTC,NGEF,NIPBL,COL4A5,SUMF2,COL9A2,MAGED1,TBPL1,CRMP1,SNCAIP,FEZ1,PHACTR3,RASGEF1C,BOC,GPRASP1,ZNF337,INTS1,PHYHIP,TOMM20,KIAA0087,DBI,DBN1,DCTN1,ZEB2,PLEKHM1,RUSC2,COPS7A,BLOC1S6,GSDME,POM121,SMG7,PLPPR4,AK5,SGSM2,TMCC2,FAM107B,DNM1,DMPK,DNM2,ATN1,PDCD6IP,DNM1L,EDN1,FAM135B,PHC2,EEF1D,EFNA3,CELSR3,EGFR,RASA4,EIF4G1,IRAK4,TNK2,EIF1,ENO2,DMTN,RASGRP2,SEZ6,ANKRD13B,EPS8,EFS,MRPL10,PIPOX,ECSIT,ZNF585B,SH3YL1,TUBB3,CORO2B,RACK1,FDFT1,PRMT5,PPP1R1B,ACTL6B,FGFR3,BAIAP2,ATP5PD,MEX3B,FOXG1,VTI1B,IQCG,FLYWCH1,NELFCD,DCTN2,DPYSL4,NBEA,TACC2,STAMBP,TRIM16,ATP6V1H,KHDRBS3,NSG2,CELF1,STAU2,SARAF,OGA,GABBR1,HIGD1B,SEPT9,SRCAP,GDF9,NFU1,GFER,SPIN1,CBX1,HTATSF1,OS9,LOXL3,GNAO1,GOLGB1,GPD1,ADAP1,NUDT21,EML4,STMN2,SPACA9,GRIK5,GSN,KAT7,ZBTB45,LINGO1,FAM107A,CELF3,HBA1,IGSF21,ZHX1,FRMD5,DDX19B,HMGB1,GABARAPL2,HMGCL,HSP90AA1,EID2B,IDH3B,LRRCC1,INPP1,INSM1,TUBB2B,ITIH2,KCNA4,KCNH2,KCNQ2,GATD1,KIF5A,KIF5C,KLC1,L1CAM,MAN2A2,MAP4,MARK3,ADAM11,GIT1,MRPL42,MSI1,PTOV1,MYO6,MYO9A,NACA,NAP1L1,FXYD6,NASP,RCOR2,NOVA1,OGG1,PCMT1,PDPK1,OLA1,CAMKV,PIK3CD,CCSER2,PKM,KCTD15,EPN1,C11orf49,RETREG2,PACSIN1,TNPO2,FSD1,PPARA,PPP5C,MAPK9,MAPK10,PRPSAP2,NDUFS7,PSD,PSMA6,GDPD2,ANKHD1,SPDL1,PTN,PTPRO,PEX2,PEX5,PLEKHB2,RAP1GAP,ROGDI,ENOX1,BEND5,BSDC1,MSANTD2,GAL3ST4,PRRT2,ARHGEF10L,SLC25A36,ROBO1,ROBO2,RPL15,FBXW7,PLPPR3,SYNDIG1,RXRA,RXRG,SAFB,ATXN2,SCN2A,TRIM46,SFPQ,TRA2B,PUF60,SCG5,SH3BP2,ITSN1,SH3GL2,SH3GL3,CCDC92,SYBU,ST3GAL3,SLA,SLC1A6,WDR47,KANSL3,SEPHS1,RADIL,ARHGEF40,CDK5RAP3,KBTBD4,SCMH1,ARFGAP1,SMARCC2,CDK5RAP2,SNAP25,SNCB,SNRPN,KDM4B,USP33,FAM219A,SPP1,SPTAN1,KIF1B,ITPRID2,EPB41L3,FCHO1,MAPK8IP3,APOM,STX1A,SEPT3,GSE1,NSFL1C,SUPT5H,NUDT10,SYN1,SYT1,SYT5,TAC1,TAC3,PJA1,TAF9,EXOC7,FAM208A,WWC1,TCF12,USP22,SLC35G2,TF,ITGB3BP,AKTIP,TMEM9,ANKRD24,TNNT1,TP53BP1,TP53BP2,WBP2,TRIO,HSPBP1,TUBB2A,UBC,UBTF,UCHL1,WNT7A,KLC2,GUSBP1,XRCC4,ZNF24,TRIM9,ZBTB16,DPYSL5,UPF3A,MAP3K12,DNALI1,RGMA,CSDE1,STMN4,TUBA1A,URM1,ITM2C,NELFE,RTN4,ACTR3B,FXR1,RNF146" Pubmed 16452087 Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Pubmed 2.61E-49 5.99E-44 4.99E-45 6.45E-44 105 214 "ABCF1,SYN3,GPRIN1,ELFN2,ADD1,ADD2,CASKIN1,LRRC7,BEGAIN,ANK1,PPFIA2,PKP4,BCAS1,PPFIA3,FUBP1,BSN,CACNA1B,CACNA1E,CACNB4,CAMK2B,CAMK2D,CAMK2G,DCLK1,ARHGAP33,EPS15L1,CLU,NGEF,TJP2,QKI,HOMER3,RBM39,SIPA1L1,CTNND2,RIMS2,FAM131B,MATR3,C2CD2L,DYNC1I1,DPYSL2,EEF1A2,EPB41L1,EPB41L2,DMTN,GPHN,SPEG,RTN3,CACNG2,PTK2B,AGAP2,RGPD5,SGIP1,NOP56,SORBS1,ABLIM2,GABBR1,GAP43,GFAP,PRRC2B,PCLO,TPPP,GRIN2D,CIT,PSIP1,SYNPO,HNRNPK,KCNB1,MAP2,MAPT,MARK1,MBP,CTNNA3,MYO5A,NCAM1,ZDHHC8,PURG,SEPT4,PRKCB,PTPRZ1,IQSEC3,RPL38,RPS20,AMER2,ITSN1,CNKSR2,SHANK2,SMARCC2,RIMS1,FNBP1,SPTAN1,CLASP2,EPB41L3,MAPK8IP3,MPRIP,SEPT8,STX1A,SEPT3,SYN1,CLASP1,TIAM1,TMPO,TSC2,PAK5,GJC2,SLC4A10,JPH3" Pubmed 16713569 A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Pubmed 1.40E-46 3.22E-41 2.48E-42 3.20E-41 184 608 "RBM10,ACTN1,ACTN2,ADCY6,ADORA1,NR0B1,C1QTNF1,LTBP4,PDZD4,BEGAIN,PPFIA4,PPFIA1,APBB1,KCNAB2,GAS7,CHRD,ATP1A3,CACNA1G,KALRN,HAP1,PTBP2,RUNX1T1,USP6,AIFM1,CBFA2T2,ENTPD6,ZBED1,NUMBL,KIAA1549L,FADS2,QKI,FHL5,PICK1,MAGED1,RCHY1,IFFO1,PREPL,NCOR1,PDE4DIP,CST3,DZIP3,PUM1,PPP6R2,ARHGAP32,TCAF1,TBC1D5,MATR3,IST1,ZNF804A,POM121,SACS,ARNT2,DMPK,ATN1,DTNA,USH1C,EDN1,PHC2,SUGP2,PLEKHO1,EPB41L2,CEND1,WAC,EFEMP1,BAIAP2,UBE2E3,PDLIM5,FYN,MEGF11,DKK3,TMEM8B,SYT17,AHDC1,PCDH17,RUNDC3A,ZNF276,RNPS1,LNX1,PRRC2B,NUDT21,RAPGEF4,CLASRP,TMEM25,CELF3,C1orf94,ZHX1,ARHGAP19,ATXN2L,ACOT7,HNRNPK,IDH3B,USP54,KPNA5,STMN1,MATN2,MBD1,MBP,MDFI,NELL1,NELL2,NOVA1,NPPA,PCBP3,PCDH8,PCSK5,C11orf49,NECAB2,FA2H,VSTM2L,PRKCG,EPDR1,APTX,QRICH1,ANKHD1,PTN,PTPRN,PTPRN2,FAT4,BEND5,UBR7,RNF220,MYH14,ROBO2,YY1AP1,ST6GALNAC6,ATXN1,ATXN2,ATXN7,SUPT20H,PUF60,SCG5,SH3GL2,SH3GL3,MYO18A,R3HDM2,SYBU,RADIL,SCMH1,SLIT1,GKAP1,SMARCC2,MAPKBP1,ZHX3,ZSWIM8,HECW1,SPP1,ZNF423,TSPYL2,LMO3,EPB41L3,SSPO,STAC2,KAZN,TAF9,CAMSAP2,AGTPBP1,TNS2,ZFPM2,TMPO,R3HDM1,KAT6B,TP53BP2,RBFOX2,IL34,PRMT8,ELP5,TRO,STXBP4,ZMYND8,HSPBP1,EIF4ENIF1,UBE3A,CCDC136,CCDC14,VSNL1,LAT2,KLC2,XRCC4,WNK1,PMEPA1,SCG2,PCBP4,WNK2,KAT6A" Pubmed 25921289 Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Pubmed 2.83E-45 6.50E-40 4.65E-41 6.00E-40 385 1922 "ABCF1,ACADM,ACLY,ACTN1,GPRIN1,ADAR,FMNL2,ADD1,KIAA1211,ESYT2,KIDINS220,AP2A1,AP2A2,AP1B1,KLHL13,WDR35,OSBPL8,AK2,TAOK1,ALCAM,ABCD2,AMPD2,OGT,CDC42BPA,ANK2,MAP4K3,PPFIA1,PARG,EPB41L5,API5,SHTN1,LGR5,MADD,CASK,ARHGDIA,CDK13,CCAR2,ATP1A1,ATP1A3,EIF4G3,ATP2A2,ATP2B1,ATP6V0A1,KIF1A,ARHGEF7,FUBP1,NAE1,AP1M1,WASF1,FOXK1,CANX,CARS,HIP1R,SPAG9,CBR1,CBS,FMNL3,CCNT1,INA,AIFM1,ARHGEF1,CDK11B,ARHGEF2,CDC27,CDH2,LRRFIP1,LRWD1,TBRG4,CLGN,COPB2,SRSF11,CHGA,EPS15L1,PLAA,COG1,CLTA,CLTC,FADS2,QKI,MAP4K4,CNN3,SLC4A7,MAGED1,SMARCAL1,CHD1L,CDC42BPB,RBM39,CRMP1,ANKRD44,CS,SEC24C,CSNK1E,PLXNA4,APPL1,CTNND1,PUM1,PPP6R2,GPSM1,DOCK4,ARHGAP32,GAPVD1,TCAF1,EARS2,TBC1D5,MATR3,INTS1,DBN1,DCTN1,MYEF2,ELMO1,HP1BP3,CEP170,ZC3H11A,GSDME,DDX46,SV2A,G3BP2,SEC16A,DNM1,MED12,TRAPPC9,DNM2,DPYSL2,PDCD6IP,GNE,TOM1,DNAJB6,DYRK1A,FARSB,DNM1L,SEZ6L2,ATL1,EEF1D,RBM12,EGFR,ABI2,RASA4,EIF4G1,EIF4G2,EIF5,COPS4,ELAVL3,ELAVL4,DCTN4,ENO2,EPB41,GPHN,SRRM1,ERCC2,MRPL37,TUBB3,RACK1,PRMT5,SEC24B,POLR1B,CAMSAP1,SEC23B,SYNCRIP,AGAP3,ANKFY1,NELFCD,DCTN2,DPYSL4,SMC2,PDLIM5,ATP2C1,MPP6,OGA,STAG2,GAA,GAB1,HBS1L,NCKAP1,SEPT9,GART,WASHC2A,USP19,TCERG1,GLDC,HTATSF1,GNAO1,GNAS,FERMT2,GPD2,NUDT21,EML4,KIF3A,MAP4K5,ATXN2L,ACOT7,HMGB1,HNRNPK,HSP90AA1,IDH3B,GAREM2,DOCK7,TUBB2B,ITGAV,JAK1,KCNH2,KIF2A,KIF5C,KLC1,IPO5,KTN1,L1CAM,LSS,MAP2,MAP4,MARK3,MAT2A,SHC3,AFDN,MOV10,GIT1,DBNL,THYN1,MTR,MYO5A,MYO6,NACA,HNRNPM,NAP1L1,NASP,NCAM1,NRCAM,NRDC,NTRK3,DDR2,NUMA1,OCRL,OGDH,OPA1,PC,PCDHGC3,PCMT1,PDE4B,PDGFRA,FAM98B,OLA1,PFKP,ABCB1,PIK3C2A,PIK3R1,XRN1,PKM,EPN1,STRN3,PSAT1,EXOSC10,TNPO2,FSD1,MED1,LRRN3,PPP5C,PRKACB,MAPK7,PROX1,PRPSAP2,PSMA6,LRRC49,QRICH1,PSMD13,PTK2,EML5,CEP97,USP47,RAP1GDS1,RDX,ZYG11B,RET,RNH1,EXD2,ELP2,RPL15,MCMBP,SAFB,SARS,SBF1,ATXN2,TRIM46,SFPQ,TRA2B,HSPA4L,PUF60,SCAF8,KIF21A,PPM1E,SHMT2,SEC31A,RPH3A,URGCP,PPP4R3A,DHX30,RAB3GAP1,ARHGEF40,CCDC88A,SLC12A2,SMARCA4,SMARCC2,IFT122,LIMCH1,SNRPN,PALLD,ZSWIM8,EMC1,UNC5B,SPTAN1,RBM26,SRPK2,CLASP2,TROVE2,LARP4,NACAD,MAPK8IP3,STAU1,PHLDB1,GANAB,STXBP1,GSE1,SYT11,ZC3H4,SUPT5H,PRRC2C,DNAJC9,SYT1,ANKRD28,SYT4,MMS19,TAF6,EXOC7,CAMSAP2,TCF4,TCF12,WASHC4,CLASP1,WDR7,SYNE1,PCDHB3,ARHGEF12,PUM2,DICER1,TJP1,LRRC8A,TMOD1,TMPO,RBFOX2,TPM3,TPM4,SYNPO2,TRIO,TSC2,HSPBP1,UBC,UBE3A,UBTF,UCHL1,PITPNB,VAV2,VGF,MICAL1,TBC1D15,WRN,KLC2,XPO1,SF1,DPYSL5,TFIP11,SMARCAD1,INTS3,CSDE1,TUBA1A,VPS35L,SNX27,FIP1L1,NELFE,RTN4,HNRNPA3,NUP214,VANGL2,AAAS,FXR1,AP3B2,LAS1L,PRRT4" Pubmed 17081983 "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Pubmed 7.86E-44 1.81E-38 1.20E-39 1.56E-38 328 1546 "ABCF1,ACLY,RBM10,CLK4,ACTN1,ARID1A,ADAR,ELFN2,ADD1,ADD3,OSBPL1A,OSBPL8,TAOK1,BCAR3,MRTFA,ZNF687,BEGAIN,AMPD2,BIN1,ANK2,ARMC12,PPFIA1,PKP4,APAF1,APC,DGKZ,API5,USP37,SHROOM2,MIER1,PRX,SPTBN4,CDK13,NUMB,CCAR2,EIF4G3,ATP2A2,ATP2B1,MPDZ,PROM1,KSR1,DST,ARHGEF7,FOXK1,CACNA1B,CACNA1D,CAMK2D,CAMK2G,CANX,CAST,SPAG9,MAP7,CERS5,CCNH,C1orf52,CDK11B,LRBA,SEPT7,KCNAB3,LRRFIP1,CLGN,NUMBL,CFL2,COPB2,SRSF11,CBARP,KMT2C,EPS15L1,NRXN3,TJP2,TMEM184B,NIPBL,CNN3,ARHGEF6,AHCTF1,CDC42BPB,RBM39,AKAP12,NCOR1,NCOR2,CSNK1E,SIPA1L1,CHD5,CALY,PHF14,CTNND1,PUM1,RIMS2,USP6NL,HDAC9,MATR3,RIMS3,TOMM20,SPOCK2,GIT2,DBN1,YTHDC1,ELMSAN1,RUSC2,C2CD2L,CEP170,MED24,ZC3H11A,DDX46,POM121,SMG7,G3BP2,WDR20,SEC16A,MED12,ABI1,ATN1,TOM1,DNAJB6,EEF1D,SIDT2,OPTN,RBM12,YAF2,EGFR,PLXNC1,EIF4G1,SORBS3,EIF5,TNK2,STARD3NL,VPS13B,EPB41L1,SRRM1,EPS8,ERBB2,RTN3,NSRP1,WAC,RPS6KC1,SEC24B,SEMA4D,NOP56,SPECC1,PDLIM5,KHDRBS3,STAG2,ZNF44,RAPGEF6,SEPT9,BRD8,RNPS1,ZNF638,CBX1,KIAA1958,HTATSF1,FERMT2,ADGRA3,PRRC2B,PRUNE2,ATF7,EML4,TUBA1C,RAPGEF1,DIDO1,CIT,CLASRP,KAT7,PACSIN2,ATXN2L,SYNPO,HNRNPK,AGFG1,HSP90AA1,IL6ST,KLC1,IPO5,STXBP5,KTN1,L1CAM,STMN1,PAXBP1,SYTL4,SMAD9,MAP2,MAP4,MBP,MIA2,MID1,AFDN,MOV10,GIT1,DBNL,CTNNA3,HNRNPM,NAP1L1,NASP,NFIA,NINJ2,NUMA1,CHAMP1,PALM,PDE4D,PDPK1,ANLN,PKD1,XRN1,PKM,PLEC,EPN1,MAPKAP1,RETREG2,SH3KBP1,MED1,PKN2,PRKCZ,MAPK3,PRPSAP2,VPS13C,TMEM104,PTK2,PTPRB,OXR1,RBBP6,DPF2,REV3L,PBRM1,CCDC82,ROBO1,CCDC25,CLIP1,RMI1,SAFB,MAPK12,CASC3,SFPQ,TRA2B,SCAF8,ITSN1,SH3GL2,MYO18A,DOCK10,CHD9,FNDC3A,ABLIM3,EPN2,RAB3GAP1,SHANK2,SCMH1,ATF7IP,SMARCA4,MAST1,SMARCC2,CDK5RAP2,SMARCD3,MYH15,RCOR3,PALLD,TMCC1,RBM34,FAM219A,SON,ZCCHC24,MYCBP2,ZC3H13,SPTAN1,KIF1B,RBM26,POGZ,ITPRID2,ERBIN,ST5,MPRIP,PHLDB1,NSFL1C,ZC3H4,SUPT5H,SYNE2,TACC1,MTCL1,TAF9,TCEA1,ZEB1,SYNE1,PUM2,SLC35G2,SIRT1,ZNF106,TJP1,CBX5,ZFP91,LRRC8A,TMPO,PARD3,KAT6B,TNS1,TP53BP1,TP53BP2,TPD52,TPD52L2,TPM3,TRIO,TRPS1,ZMYND8,TSC2,UBC,BCL2L13,MICAL1,TBC1D15,CLIP2,NSD2,KLC2,KCNK12,SF1,ZNF142,ZBTB38,TFIP11,SMARCAD1,WNK1,CA10,PRDM2,CSDE1,TUBA1A,NAV2,FIP1L1,NELFE,RTN4,KAT6A,NUP214,TTC7A,FXR1,GAN,SENP7" Pubmed 14621295 Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 4.68E-43 1.08E-37 6.72E-39 8.69E-38 160 508 "RALGAPA1,PLEKHG5,MTA3,ZNF608,INTS2,MTUS1,HECW2,CASKIN1,CEP126,ARHGAP20,CARNS1,KCNT1,SYT13,ZNF687,PITPNM2,CDC42BPA,EP400,USP28,PHF12,CACHD1,MIER1,KIAA1614,ZFYVE28,CAPRIN2,ATP1A2,ADGRB3,SYNJ2,ARHGEF7,CACNA1G,BSN,HIP1R,FMNL3,ZMYM4,TBRG4,TAOK2,KMT2C,NRXN2,MAP4K4,AKAP6,CLOCK,PREPL,PLCH2,CHD5,CNTNAP2,SDC3,RIMS2,USP6NL,GAPVD1,EARS2,KIF26A,MATR3,MAML1,TOMM20,SCRN1,HEPH,MYEF2,TIAM2,DDX46,SMG7,PLPPR4,KBTBD11,CASP8AP2,PDCD6IP,RBM12,CELSR3,ERBB2,ADGRV1,MED12L,AMOTL2,SEMA6C,FLYWCH1,CAMKK2,HHIPL1,OGA,DENND2A,BRPF3,SRRM4,KIAA1841,TNRC6A,KDM2B,CECR2,DIDO1,HPS5,PADI2,SYNPO,SHISAL1,IGSF1,NACA,CHAMP1,PALM,CDK14,SEMA5B,CCSER2,FTO,PLXNB1,SDK2,PACSIN1,VPS13C,SNRK,ANKHD1,RALGDS,ERI2,ARHGEF10L,ROBO2,SBF1,KIF21A,KIF16B,AMBRA1,FNDC3A,DZIP1,WDR37,URGCP,KANSL3,CCDC88A,TET1,CDK5RAP2,FAIM2,KDM4B,KIF21B,KDM3A,NMNAT2,EMC1,CAND2,TEX2,ARHGAP26,NFASC,POGZ,ZC4H2,SEPT8,SULF2,ACSBG1,ZC3H4,PLCB1,DNMBP,IQCE,SMG6,MGRN1,SATB2,ZFP90,WASHC4,SZT2,AKNA,CRTC1,PCDHA3,SIK3,DICER1,DDHD1,LRRC8A,AMOT,NSD2,TRIM9,NDRG4,SH3GLB2,SPIRE1,STOX2,HPS4,NAV2,WNK2,RTN4,VANGL2" Pubmed 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 1.01E-42 2.31E-37 1.36E-38 1.76E-37 118 301 "ACHE,ACTN2,ADCYAP1R1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,CNTNAP1,PDXK,ASTN1,CCK,CCKBR,CHRM1,CHRNB2,NRXN3,NRXN1,NRXN2,CNR1,PICK1,CNTFR,CNTN1,NRG2,CRHBP,CNTNAP2,DBI,MAGI2,SNAP91,DLG2,DLG3,GRIN3A,DRD1,EGFR,PPP1R1B,NBEA,NRG3,GABBR1,GABRA1,GABRA2,GABRA3,GABRA5,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GALR1,DISC1,GLRB,RAPGEF4,GRIA1,GRIA2,GRIA4,PLCD4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,NR3C1,GRM2,GRM3,GRM5,GRM7,HTR2A,HTR5A,INPP1,L1CAM,MAOB,NCAM1,NCAM2,NEUROD1,NEUROD2,NOS1,NPY,NPPA,NPR2,NRCAM,NTRK2,NTRK3,OXTR,PAH,CNTN3,PDYN,PENK,ABCB1,PLCD1,RELN,PTN,S100B,SHMT2,NLGN1,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A9,SLC6A11,SNAP25,SST,SSTR1,SSTR2,SYN1,ASTN2,TAC1,TAC3,TACR1,CNTN2,TRH,NTSR2,TSC2,UBE3A,VIPR2,TFIP11,SLC17A7,SLC17A6" Pubmed 12168954 Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. Pubmed 3.72E-42 8.55E-37 4.75E-38 6.14E-37 100 225 "DSCAML1,ADCY6,ESYT2,AP2A2,ZNF608,GPR158,WDR35,OSBPL8,MRTFA,APAF1,ALS2,TNRC6C,PPFIA3,CADPS,ADGRB3,DST,SYNJ1,CACNA1G,BAIAP3,THSD7A,SPAG9,KMT2C,NRXN1,NRXN2,AKAP6,CDC42BPB,AATK,TENM4,ARHGEF10,SIPA1L1,CHD5,PPP1R16B,ERC2,APPL1,ARHGEF4,TOX,SCRN1,GIT2,ZBTB24,HEPH,C2CD2L,SMG7,SRGAP3,TMCC2,SEC16A,CASP8AP2,RBM12,ADGRV1,ANKFY1,CAMKK2,OGA,ERAP1,WASF3,NTNG2,PRUNE2,HPS5,PACSIN1,SNRK,DOCK10,FNDC3A,SLIT1,UNC80,KDM4B,MYT1L,TNIK,ZHX3,HECW1,MYCBP2,ERC1,CDK19,NFASC,TAB2,ERBIN,CEP68,PHLDB1,SULF2,MLC1,ZC3H4,SYNE2,PLCB1,ANKRD28,CAMTA1,SMG6,DMXL2,CUX2,SYNE1,DOCK9,PSD3,OBSL1,PUM2,SIK3,DICER1,KAT6B,AMOT,CLIP2,TRIM9,NDRG4,WNK1,NAV2,TTC7A" Pubmed 8619474 "A ""double adaptor"" method for improved shotgun library construction." Pubmed 1.15E-41 2.65E-36 1.39E-37 1.80E-36 169 569 "ASPHD1,ADCY2,ADD2,SLC12A5,MARCH4,BIN1,OGT,ANK2,APBA2,APC,MARCH3,BRINP2,CHRD,ATP2B1,MTMR9,KIF1A,ADAM23,BCS1L,BAIAP3,ZNF555,CAMK2B,CANX,RUNX1T1,METTL6,AIFM1,DCLK1,ARHGAP22,DLGAP3,CLCN4,FAM19A5,COX4I1,ABCG1,MICAL2,CTNND2,RIMS2,HDAC4,KIAA0513,MATR3,ZNF804A,CNIH3,FBXL5,BLOC1S6,GSDME,SNAP91,SV2B,G3BP2,DNM1,CALN1,DMTF1,RCAN1,DTNB,SEZ6L2,WDPCP,FAM135B,ATL1,ANKRD46,OPTN,PLXNC1,LINC00599,BSCL2,EML1,EPB41L2,STX2,ERBB4,NCALD,CEP85L,ETV1,REEP2,ATP8A1,OLFM1,IP6K2,SEMA6C,EVL,STAMBP,NPTN,B3GAT1,SDCBP2,DKK3,AHCYL1,TMEM8B,MYOZ2,AHDC1,MMADHC,CSDC2,MALT1,RUNDC3A,NTNG2,PCDH11X,GPD2,EML4,GRM5,FAM107A,PACSIN2,ARHGAP19,ATXN2L,HLF,ELOVL5,LINC00667,C2orf72,TUBB2B,HECTD2,ARHGAP12,MAP4,MMP16,PTOV1,SAMD14,NF1,NTRK3,OPCML,KCNK10,PAK3,CCSER2,FAM216A,FTO,HMGCLL1,PLTP,SCHIP1,NECAB2,MAPK10,WBP1L,RGS3,LGI2,MEG3,RXRA,SEC14L1,ZNF821,STUM,ST6GAL1,SLC1A2,SLC1A3,SIRT2,SHANK2,ZNF415,KDM4B,FAM219A,SPP1,PEG10,NFASC,LARP4,AJAP1,ACSBG1,SUPT5H,VPS13A,MMS19,KAZN,KIAA0930,RALYL,PCDHB10,OBSL1,DICER1,CDH22,TIAM1,MTMR14,TJP1,BHLHB9,TMOD1,TMPO,KCTD2,UBC,FRRS1L,FLRT1,TOM1L2,MEAF6,ZIC1,NDRG4,PLPPR5,CSDE1,WIPF2,FAM13C" Pubmed 9110174 Large-scale concatenation cDNA sequencing. Pubmed 1.72E-40 3.95E-35 1.97E-36 2.55E-35 166 563 "ASPHD1,ADCY2,ADD2,SLC12A5,MARCH4,BIN1,OGT,ANK2,APBA2,APC,MARCH3,BRINP2,CHRD,ATP2B1,MTMR9,KIF1A,ADAM23,BCS1L,BAIAP3,ZNF555,CAMK2B,CANX,RUNX1T1,METTL6,AIFM1,DCLK1,DLGAP3,CLCN4,FAM19A5,ABCG1,MICAL2,CTNND2,RIMS2,HDAC4,KIAA0513,MATR3,ZNF804A,CNIH3,FBXL5,BLOC1S6,GSDME,SNAP91,SV2B,G3BP2,DNM1,CALN1,DMTF1,RCAN1,DTNB,SEZ6L2,WDPCP,FAM135B,ATL1,ANKRD46,OPTN,PLXNC1,LINC00599,BSCL2,EML1,EPB41L2,STX2,ERBB4,NCALD,CEP85L,ETV1,REEP2,ATP8A1,OLFM1,IP6K2,SEMA6C,EVL,STAMBP,NPTN,B3GAT1,SDCBP2,DKK3,AHCYL1,TMEM8B,MYOZ2,AHDC1,MMADHC,CSDC2,MALT1,RUNDC3A,NTNG2,PCDH11X,GPD2,EML4,GRM5,FAM107A,PACSIN2,ARHGAP19,ATXN2L,HLF,ELOVL5,LINC00667,C2orf72,TUBB2B,HECTD2,ARHGAP12,MAP4,MMP16,PTOV1,SAMD14,NF1,NTRK3,OPCML,KCNK10,PAK3,FAM216A,FTO,HMGCLL1,PLTP,SCHIP1,NECAB2,MAPK10,WBP1L,RGS3,LGI2,RPL15,MEG3,RXRA,SEC14L1,ZNF821,STUM,ST6GAL1,SLC1A2,SLC1A3,SIRT2,SHANK2,ZNF415,KDM4B,FAM219A,SPP1,PEG10,NFASC,LARP4,AJAP1,NSFL1C,ACSBG1,SUPT5H,VPS13A,MMS19,KAZN,KIAA0930,RALYL,PCDHB10,OBSL1,DICER1,CDH22,MTMR14,TJP1,BHLHB9,TMOD1,TMPO,KCTD2,UBC,FRRS1L,FLRT1,TOM1L2,MEAF6,ZIC1,NDRG4,PLPPR5,CSDE1,FAM13C" Pubmed 27626380 High-throughput discovery of novel developmental phenotypes. Pubmed 7.30E-40 1.68E-34 7.99E-36 1.03E-34 331 1634 "SYN3,C3orf14,ADAR,ELFN2,SLITRK1,RNF157,ADCYAP1R1,ESYT2,PTCHD1,LRFN2,SLC24A4,AP2A2,GPR158,CASKIN1,HACE1,KIAA1324,ADGRF5,SPOP,BBOX1,DPP10,PKP4,CNTNAP1,CPNE5,AQP6,ZFYVE28,ARRB1,ARRB2,DACT3,TMEM108,CCDC181,ATP1A3,STX16,ATP2A2,ATP2B1,ATP6V0A1,ADAM23,BACH1,SYNJ1,NAE1,JAZF1,CACNA1I,GPC2,IL33,LDLRAD4,BTRC,CA4,CACNA1B,VXN,CAST,CH25H,HIP1R,RHBDL1,CCK,KRIT1,FMNL3,CERS5,USP2,P2RX6,SCARB1,AP4M1,KCNAB3,CDH10,ARHGAP33,CHN1,CHRNB2,ZBED5,JAM2,PPT2,NRXN1,CLU,ABCG2,TMEM184B,HECTD1,CNR1,COL9A2,COX4I1,CP,HAPLN1,CRYM,CS,CSF3R,ARHGEF10,GREB1,GPSM1,CYBB,BOC,SNPH,RIMS3,DAPK1,AIF1L,SIRPA,DBN1,DCC,SPATA2,DCT,ZBTB24,PLEKHM1,KIAA0753,KLHL3,USP3,ATN1,DNM1L,SEZ6L2,SNX29,HEYL,LPAR6,EIF4G2,EPB41,NCALD,SPEG,PIPOX,ADGRV1,EZH1,CLVS1,ABCA8,PRAM1,EFEMP1,SLC9B2,FGFR1,BAIAP2,HPCAL4,CAP2,RGPD5,FOXO3,EVL,SEMA4D,SGIP1,CINP,USP16,FAM49B,KHDRBS3,NSG1,HHIPL1,FYB1,GAD2,GALC,IQGAP2,SYT17,STARD10,GART,DNER,GATM,ALDH1L1,GHR,TOX3,PCSK1N,GNAO1,GP1BB,TDRKH,GPR17,GPR22,TPPP,PARD3B,ADAMTS13,GRM3,ZNF496,BVES,MFSD2A,RABL2A,GYG1,RASSF8,PADI2,FRMD5,PACSIN2,ARHGAP19,GABARAPL2,NEGR1,HSD17B1,HSF2,IRF8,PLD5,USP54,IL6R,IL6ST,INPP1,LRRTM3,KCNA1,KCNB1,KCNC2,KCNJ3,KCNJ9,LIFR,HECTD2,FGFBP3,NCOA7,LSS,C2orf80,MAG,MAPT,LYPLAL1,MAT2A,CHST6,POC1B,MMP16,BLOC1S2,MYO9A,TCEAL5,NEFH,NRCAM,NTRK2,IGSF11,OXTR,P2RX7,PC,PCSK1,PCSK5,PDCD2,PDE1B,PENK,PFKFB2,PFKFB4,PIK3C2A,KCTD15,GPSM2,FAM216A,PLCB2,PCDH18,PRIMPOL,MAPKAP1,STRN3,SPATA6,MBOAT7,EPB41L4B,TATDN3,PPP2R2B,PTPA,PRKAB2,PKIA,RAB39A,EPDR1,PRODH,NDUFS7,VPS13C,SIDT1,USP47,SH3TC2,IQSEC3,RDX,RLBP1,RIC8B,CARF,GSTCD,TMEM100,SNX22,NEK11,EPHA10,SGSM1,PAQR6,RTN1,SATB1,ASIC4,ELMOD1,CASC3,SH3BP2,SH3GL2,MYO18A,ANKRD6,NUBPL,CLSTN1,SLC1A3,RPH3A,SLC2A5,PEX26,DHX30,SLC8A3,SLC20A2,SLIT1,MAPKBP1,LMBRD1,ZHX3,DBNDD2,KIF1B,TSPYL2,THSD1,SMOC1,SST,DIP2A,AJAP1,MLC1,JMJD6,RHBDL3,VPS13A,DNAJC9,SYPL1,POPDC3,ADGRL3,IQCE,TMEM136,VWA3A,SATB2,TPCN2,USP22,TMEM151B,DICER1,SIRT1,CHST8,AP4E1,AKTIP,SLC44A1,FBXL16,GALNT17,ARL10,THRA,NACC2,DAAM2,PARD3,SEZ6L,ZNF346,SYNPO2,TRPC3,NUTM2A,SSBP2,TST,UBE2H,FRRS1L,SLC13A3,ELFN1,NDRG4,LYPD6,FTSJ1,DHX33,GDPD5,PRDM10,SNX27,CAB39L,ITM2C,PARP11,C12orf4,FZD3,FBXO36,IFT88" Pubmed 21900206 A directed protein interaction network for investigating intracellular signal transduction. Pubmed 2.94E-39 6.74E-34 3.07E-35 3.96E-34 255 1123 "CPNE2,CCDC85A,ADD1,TBC1D14,TAOK1,CEP126,GPRASP2,AMPH,LRFN1,LCORL,PKP4,ANXA7,APBA2,APBB1,APLP1,DGKZ,DGKD,APOC1,SPTBN4,ARHGDIA,DYNLL1,TMEM108,EIF4G3,NOL4,BCS1L,BID,BTRC,CA12,DDR1,HAP1,SPAG9,CBS,ARHGEF1,ENTPD6,ZBED1,CDC42,UBE2L6,CHGA,CHGB,CHN1,CHRNA4,CNOT8,KMT2C,CPNE6,NRXN2,NMT2,CLTA,NGEF,ARHGEF6,CNTFR,CNTN1,ARMC8,COL4A5,ANKRD35,COL11A2,ZFP28,AKAP12,CRMP1,CRYM,SNCAIP,FEZ1,CSNK1E,PDE4DIP,PHACTR3,UBXN2A,CTNND2,EDRF1,KIAA0408,MATR3,DBI,DBN1,DCTN1,PLEKHM1,TIAM2,FBXL5,MED24,DNM1,DMPK,DYNC1I1,DNM2,DPYSL2,PDCD6IP,PHC2,EEF1A2,KLHL5,EIF4G1,EIF1,SEZ6,RABEPK,EPS8,MRPL37,VPS26C,TUBA1B,TUBB3,RACK1,ACTL6B,FHL1,MEX3B,HPCAL4,IQCG,FOXO3,DCTN2,DPYSL4,UFM1,FAM49B,NPTN,ZNF605,NSG2,OGA,FYN,INPP5K,TUBGCP4,GDF9,PSRC1,GPM6A,ADAP1,NUDT21,STMN2,GRB10,SPACA9,NR3C1,KAT7,PSIP1,MAP4K5,CELF3,HBA1,IGSF21,ZHX1,NXPH3,MAN1B1,HMGB1,GABARAPL2,HMGCL,IDH3B,RBPJ,DOCK7,INPP1,TUBB2B,KLHL23,KIF5A,KLC1,STMN1,SMAD1,MAP4,SHC3,MEST,MPP2,GIT1,BLOC1S2,NAP1L1,NASP,NELL2,NEUROD2,NOVA1,PCDH8,PDE1B,PDPK1,PFKFB4,SEMA5B,NOMO2,CCSER2,PKM,C11orf49,PSAT1,RETREG2,MBOAT7,SH3KBP1,PPP3CA,PPP5C,PKN2,PRKCZ,MAPK3,MAPK8,MAPK9,PRPH,MASP1,PTK2,PTN,PTPRO,PEX5,RIPOR1,RAP1GAP,ROBO2,YY1AP1,ZNF671,RXRA,RXRG,ZNF331,RMI1,SAFB,SBF1,TRIM46,ASRGL1,ITSN1,SH3GL2,SH3GL3,SEC31A,PAAF1,SLA,RUFY2,ARFGAP1,ZNF667,SNCA,FAM219A,KIF21B,BEX1,SPTAN1,NACAD,STAU1,SEPT8,SEPT3,NSFL1C,ACSBG1,SYNE2,SYT5,TAC1,MCF2L,KIAA1107,WWC1,FBXW11,TCF4,USP22,ATP13A2,ITGB3BP,SLC44A1,FBXL16,CBX5,TNNT1,TNS1,TP53BP2,TPM3,RUNDC3B,ZMYND8,TSC2,TTC3,ZKSCAN5,TUBB2A,UBC,UBE3A,GORASP1,OSBP2,CCDC136,VAV1,MICAL1,KLC2,CFAP298,TCEAL7,ZBTB16,MAP3K12,DNALI1,TUBA1A,CIAPIN1,RTN4,JMJD1C,ADAMTS10" Pubmed 15368895 Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 3.99E-39 9.17E-34 3.99E-35 5.15E-34 147 471 "NDRG2,FMNL2,ELFN2,GALNT16,SLITRK1,CCDC85A,PWWP2A,AP2A2,KIAA1324,WDR35,OSBPL8,DISP3,TXNDC16,TAOK1,ADGRF5,FAM135A,EPB41L5,GAS7,GPAM,DGKD,USP37,SLC7A14,SEMA4G,PRX,PPP4R4,CDK13,DNAH17,BCL2L2,SCAPER,THSD7A,BRSK2,SPAG9,DIS3L,HECTD1,SLC4A8,ZFP28,PNKD,CDC42BPB,SH2B1,CRY2,GDA,OSBPL3,ATRNL1,SOCS5,FAM169A,SLITRK5,APPL1,PHF14,PPP6R2,HDAC9,ARHGAP32,TCAF1,RASSF2,KIAA0586,IP6K1,CTIF,ARMCX2,YTHDC1,KIAA0753,CEP170,POM121,RHOBTB1,TMCC2,GRIN3A,MED12,TRAPPC9,DOCK2,SH3GLB1,ABCA8,WAC,KIAA1109,MEX3B,PCYOX1,ATP2C1,ZNF512,NEURL4,HBS1L,ACSS1,TTBK1,GLS,PRUNE2,LRRCC1,SCIN,MARK1,MOV10,MYO6,NEK1,NFIA,NLGN3,SSH1,PCDH18,PDZRN4,SYTL2,SH3TC2,RAP1GAP,ATP8B4,SEC14L1,ZFP30,NTNG1,MAGI3,ANKRD6,CLSTN1,ABLIM3,PPP4R3A,EPN2,RUFY2,FAM214B,RADIL,RAB3GAP1,CPEB4,MBD5,PALLD,TMCC1,PDZRN3,UNC80,SCN3B,DOP1A,SP2,HECW1,KDM4C,EPB41L3,FCHO1,CEP68,RGL1,ASTN2,ATP11A,KAZN,DDHD2,EXOC7,FAM208A,EHBP1,SIN3B,DMXL2,KIAA0930,FAM189A1,GPRIN3,BHLHB9,ANKRD24,ZKSCAN5,FLRT2,PLEKHH2,CLIP2,RICTOR,WNK1,ADAMTS9,JMJD1C,RSPRY1" Pubmed 23251661 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Pubmed 3.50E-37 8.05E-32 3.35E-33 4.33E-32 203 817 "ASIC2,ADCY5,GALNT13,ADORA3,LRFN2,SORCS2,CC2D2A,LRRC7,KIF6,DPP10,PKP4,CDK5R2,CA8,CACNA2D1,CACNB2,CAMK2A,SYT6,CBS,CDH2,DCLK1,DLGAP1,CHN2,RAB28,CLTB,SRP14-AS1,NIPBL,WHRN,AATK,CSF1,TENM4,SIPA1L1,RIMS4,CNTNAP2,UBXN2A,GREB1,USP6NL,NOS1AP,HDAC9,ARHGAP24,TOMM20,SCRN1,DBI,DCC,YTHDC1,ZNF804A,C8orf34,ZEB2,MAGI2,PARD6A,SPOCK3,NTM,KBTBD11,DLG2,GRIN3A,HS3ST4,TRAPPC9,DYNC1I1,DRD1,DSCAM,ABCC9,EBF1,SNX29,WDPCP,EDNRA,MBNL2,ASB3,ELAVL4,C8orf37,EMX2,TUBD1,ADGRV1,ZNF585B,DLC1,OLFM1,TACC2,SORBS1,SPECC1,AK8,AP4B1,NRG3,CHL1,GABRB1,GALR1,SRRM4,CPLX2,GRIA1,GRIK2,PRDM5,FAM19A2,FICD,GUCY1A2,RNFT2,HAS2,NCKAP1L,BACH2,HPSE2,SHISA6,ICA1,IFI16,PLD5,C2CD4C,CDH20,KCNB1,KLHL23,KCNN2,KCNN3,VWA5A,ASPRV1,MATK,SAMD5,CTNNA3,WDR11-AS1,LAYN,NAP1L1,NELL1,CCDC13,SETD4,IGSF11,PCSK2,PDE4D,FAM218A,KCTD15,PCDH18,HMGCLL1,ANKRD16,PSAT1,MBOAT7,SLC36A4,NXPH1,POU3F2,DCHS2,BCAS3,SLC22A23,SNRK,MDGA2,PTPRD,PTPRN2,SLC25A48,RBBP6,GTDC1,RGS7,ARHGEF10L,TTLL7,KIF7,RNASE1,CYB561D1,KIRREL1,LRRK2,SCG5,SH3GL2,MAGI3,FHOD3,BTBD3,PKNOX2,SLC8A1,RADIL,TRIM67,SHANK2,TMEM132D,SLIT1,CPEB4,IGSF9B,CABCOCO1,SNRPN,MYO16,PDZD2,BDP1,SOX11,NMNAT2,HECW1,KDM4C,SPTB,LHPP,SS18,MPRIP,ZC3H4,SYT1,ASTN2,FAM189A1,SLC19A3,PSD3,TLR4,TMOD1,CSMD1,TSC2,CADM1,FAM155A,UBE3A,RICTOR,AGMO,DPYSL5,ANKS1B,PLPPR5,PMEPA1,PRTFDC1,TMEM178A,NAV2,MVB12B,DOCK8,PAK5,PHTF2,ACTR3B,FAM198A" Pubmed 15342556 Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Pubmed 6.76E-37 1.55E-31 6.22E-33 8.03E-32 258 1178 "KLHL13,PLA2G6,SYT13,ANK3,APC,GAS7,ALS2,CDC14B,ARSE,ARSF,ZNF583,ATP6V1G2,RIPK1,BCL2L2,BCS1L,BLM,DST,SYNJ1,MTMR2,CACNA1E,CACNB2,CACNB4,ZNF501,CCNH,SLC16A4,MYOM2,SEPT7,CDC27,DIS3L,SRSF11,FOXN3,TAOK2,KMT2C,CLCN3,CLCN4,CLU,TPP1,AKAP6,SLC25A27,SUMF2,RCHY1,GAL3ST1,COX4I1,ACBD5,CPS1,CREM,MROH8,VCAN,PDE4DIP,CTNND1,RIMS2,GPRASP1,DCAF8,DAPK1,SPOCK2,DBI,DNAJC6,DCT,ZEB2,HEPH,TIAM2,CEP170,LYPD1,SV2A,WDR20,CHRDL1,DLG4,DYNC1I1,CASP8AP2,DPYSL2,GNE,DNM1L,E2F5,FSD1L,GOLGA7,ELAVL2,ING4,BSCL2,ELN,RCAN2,SIRPB1,EXTL2,GMPR2,DLC1,ATP8A1,FKTN,KAT8,TMEM164,SEC23B,IP6K2,COQ5,POMT1,SPECC1,HVCN1,APOPT1,UFM1,PDLIM5,ZNF512,FYB1,SDCBP2,NEK6,ERAP1,SIGLEC8,ZNF559,MYOZ2,PCDH17,DHRS4,RAB30,ZNF638,GNAL,PSRC1,GOLGB1,ATF7,LILRA2,GRIA2,PLCD4,MFSD2A,FAM107A,IRAK3,VSIG4,SYNPO,CPT1C,OPALIN,KLC1,LIFR,LMO1,SYTL4,MDM4,MEF2C,SRSF12,MT3,ZNF92,CTNNA3,MYBPC1,MYH3,MYL3,NCF2,NEFM,NF1,NFIX,NME4,OLR1,OPHN1,PALM,PDE1B,BEST3,NLGN3,GDAP1L1,SSH1,KCTD15,NLE1,PLCL1,PLEC,ZNF426,PRIMPOL,PMS2,SH3KBP1,PPARA,MED1,PPP1R1A,PPP2R2B,CRLS1,NKAIN4,HYDIN,KLK6,SNRK,SPDL1,PEX2,PLEKHB2,RAP1GAP,BSDC1,DPF2,REV3L,RGS3,KCTD17,SEC61A2,CCDC82,ROBO1,TCP11L1,PTGR2,PAQR6,ATAT1,RYR1,NCBP3,FAM192A,RMI1,SALL1,SARS,ATXN1,ATXN7,SCN2A,ASRGL1,SCG5,SH3GL3,CNKSR2,NUBPL,ABLIM3,PEX26,LIMS2,KANSL3,SLN,ZFP1,COA1,OGDHL,RCOR3,INAVA,SCN3B,BDP1,UNC5B,PEG10,DBNDD2,SPTAN1,KIF1B,MESP1,ZC4H2,ERBIN,RGL1,KANK1,SUPT5H,ARHGEF9,TAC3,ANKRD12,EHBP1,TCF4,TPCN2,CYB561A3,DNAH7,DICER1,ZNF34,HEY1,CBX5,ZFP91,CSMD1,TP53BP1,TPD52L2,ZNF384,ELP5,TSN,TTC3,UBTF,UCHL1,CCDC14,WRN,KLC2,RICTOR,SLC13A3,TMEM237,ZNF177,ANKS1B,CSDE1,EVI5,PRDM8,VPS35L,PLSCR4,KAT6A,PHTF2,SSPN,SPATA13" Pubmed 21832049 "Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein." Pubmed 3.12E-36 7.17E-31 2.76E-32 3.56E-31 357 1891 "DGCR6,ABCF1,ABR,ACLY,FMNL2,KLHL32,ADD2,CDC7,ERMN,DPY19L2P4,AP2A2,BCAR3,PDZD4,BEGAIN,BIN1,EPB41L5,GPAM,PHYHD1,VAT1L,APP,MIER1,PLA2G4C,ASGR1,MARCH3,STK33,ASPH,ZSCAN18,NUMB,RASL11B,ALDH4A1,CHID1,ALDH7A1,BMPR1B,CDK5R1,BTK,GYG2,DIRAS1,TRIM41,SYT6,CARS,KYAT1,FMNL3,USP6,USP2,P2RX6,CBFA2T2,KCNAB3,DCLK1,L3MBTL4,CIART,CHGB,LSMEM2,SLC22A6,RAB28,NMT2,STOML1,QKI,LY86,RAB26,HOMER3,PCYT1B,LETMD1,GAL3ST1,TBPL1,COX4I1,TCEAL2,PNKD,RBM39,HAPLN1,TRIM69,MROH8,SEC24C,CSNK1E,SOCS5,RIMS4,CTNND1,PPP6R2,USP6NL,NOS1AP,ARHGAP24,HDAC4,KIAA0513,ZFYVE16,SPATA2,ZEB2,HP1BP3,MED24,BLOC1S6,GUCD1,NTM,TMCC2,ARNT2,DMD,DNM2,RCAN1,TOM1,DNAJB6,DYRK1A,E2F6,TSPAN5,SGK2,HEYL,FSD1L,SH3GLB1,GPR61,PHF20L1,EIF5,TMEM35A,EIF1,EPB41L1,EPB41L2,DMTN,RASGRP2,KCNMB2,IGSF6,EFS,SPEG,SRARP,CDKL3,MRPL10,RASL12,RRAGB,NSRP1,WAC,CACNG3,CACNG2,ACSL4,ST3GAL6,FCGR3A,GORAB,OLFM1,FGF12,ACTL6B,BAIAP2,ATP5PD,SYNCRIP,TMEM175,ZCCHC17,CINP,TRIM16,CAMKK2,CELF1,HRASLS5,GABRA4,HBS1L,SYT17,SEPT9,STARD10,CPLX2,KIAA1841,MSTN,AHDC1,GFAP,GJB1,MSL3,AIFM3,POLL,RAB40B,FERMT2,GPT2,LNX1,PSRC1,PRRC2B,CNDP1,GPR12,TPPP,GRB10,DIDO1,PLCD4,ANKRD36BP1,KIF3A,CLASRP,KAT7,AP4S1,GUCY1B1,RASSF8,TOX2,DDX19B,KLF12,VSIG4,GABARAPL2,AGFG1,SMAP1,ATCAY,IFI16,RBPJ,NIM1K,INPP5B,OLFM3,KCNJ10,KCNN3,GATD1,KIFC3,VWA5A,PACRG,SMAD1,MAG,ZFYVE27,MAP2,MBD1,MBNL1,MDM4,MEIS2,MEST,MITF,MOBP,MSI1,BLOC1S2,MX1,MXI1,NDP,NDUFA5,NFYA,NNAT,NOVA1,SMIM11A,NTRK3,ODF2,OPA1,PCDHGC3,CDK18,PDE1A,PDE4D,PDPK1,PDYN,TMOD2,CAMKV,CCSER2,RETREG1,PKM,PLCD1,PSAT1,ING3,POLR2F,C19orf57,PTPA,PPP2R5C,PPP2R5E,PPP3CC,PPP5C,RAB39A,PRKCG,MAPK7,MAPK8,MAPK10,PRPSAP2,PIGG,PTK2,PTPRO,PEX2,TMEM255A,CCDC40,ATG16L1,FAM184A,BEND5,ZMAT4,GTDC1,RGS3,RGS10,TTLL7,RIT2,MRPS18A,RLBP1,PBRM1,DCUN1D2,CARF,PNMA8A,MRAP2,NEK11,TCP11L1,RPS20,ATAT1,RTKN,NCBP3,DGLUCY,COPZ1,RASA3,SH3GL2,SHMT2,FNDC3A,ZNF365,LIMS2,FAM214B,ARHGEF40,ARFGAP1,CXXC4,RCOR3,LIMCH1,SNAP25,SNCA,FAM126B,SOX5,SPATA7,TSNAXIP1,SP2,NMNAT2,CLUAP1,TEX2,ERC1,SPART,SRPK2,TAB2,POGZ,SSTR2,LARP4,NXT2,FCHO1,INKA2,STAU1,RGL1,STXBP1,ACSBG1,NECAB1,DDHD2,TAF6,TAF9,TCEA1,KIAA0930,PCDHGC5,ARHGAP9,PCDHA7,TEK,SPX,ITGB3BP,ZMAT3,MTMR14,BHLHB9,PIK3R5,NPL,RUSC1,KCNE5,HSPBP1,TTPA,SGK3,UBE3A,AMOT,DNAJC12,BCL2L13,TOM1L2,CCDC14,VIPR2,NSD2,KLC2,ETNPPL,CFAP298,ZNF23,CELF4,ANKS1B,FTSJ1,ZFAND5,UPF3A,INTS3,DNALI1,KCNAB1,FIP1L1,PDSS2,HRASLS" Pubmed 20936779 A human MAP kinase interactome. Pubmed 3.87E-36 8.90E-31 3.30E-32 4.26E-31 145 486 "NCKAP5,ACTN1,FMNL2,CDC42BPA,ANK3,MAP4K3,ANXA7,APC,GAS7,MADD,ARHGDIA,ARRB1,ARRB2,SLC4A4,RIPK1,PROM1,DST,SYNJ2,ARHGEF7,BTK,ARHGEF1,CDC42,ARHGAP33,MAGI1,DLGAP1,KMT2C,KIAA1549L,CLTC,MAP4K4,ABI3BP,CDC42BPB,ARHGEF4,PYGO1,HDAC9,ARHGAP32,RIPOR2,HDAC4,KIF26A,ELMSAN1,DCTN1,BLOC1S6,POM121,DMD,SHANK1,CASP8AP2,PDCD6IP,HIPK3,TNK2,EPB41L2,BAIAP2,CAP2,FLNC,DCTN2,SORBS1,STAMBP,ABLIM2,GAB1,GFAP,TCERG1,TNRC6A,GLUL,OS9,GOLGB1,CNTRL,RAPGEF1,KIF3A,MAP4K5,ZHX1,PACSIN2,SYNPO,HNRNPK,AGFG1,HSP90AA1,KIF5A,KTN1,MEF2C,STK32C,MYO6,MYO9A,HNRNPM,NFYA,PAK3,PIK3R1,PLEC,PACSIN1,KANSL1,PRKAR1B,PRKCZ,MAPK7,MAPK9,MAPK10,PTK2,RALGDS,RAP1GDS1,RBBP6,ROBO1,YY1AP1,ATXN1,SFPQ,SUPT20H,ITSN1,MYO18A,CCDC92,SEC31A,SLC1A2,PPP4R3A,CCDC88A,ATF7IP,MBD5,SPTAN1,RAP1GAP2,POGZ,ITPRID2,EPB41L3,SS18,ERBIN,RGL1,ARHGEF9,PLCB1,COBL,EHBP1,SYNE1,CRTC1,SIK3,ZNF106,ANKRD24,TNS1,RBFOX2,TPM4,SYNPO2,UBC,TOM1L2,CCDC14,WIPF1,CLIP2,ZNF142,WNK1,CSDE1,HPS4,NAV3,NAV2,WIPF2,WNK2,PAK5,NUP214" Pubmed 15618518 Mouse brain organization revealed through direct genome-scale TF expression analysis. Pubmed 2.45E-35 5.63E-30 2.01E-31 2.60E-30 327 1689 "DPF1,SERPINA3,RBM10,KDM5D,ARID1A,NDRG3,NDRG2,RNF157,BRAP,MTA3,NR0B1,OSBPL6,MRTFA,ZNF687,ZFAT,LCORL,PHF12,ARNTL,ASCL1,NCOA1,ATP1A1,ZNF583,KIF1A,BACH1,BARD1,SCAPER,JAZF1,FOXK1,LDB2,CERS5,ZMYM4,ZNF445,CNOT8,LHX2,KMT2C,VAX2,FHL5,CNN3,TBPL1,AHCTF1,ZNF521,ZFP28,ZNF385A,CLOCK,CREM,CREB5,RNF14,HINFP,NCOR1,CLIP3,TRIM69,PHF14,ST18,PYGO1,TOX,PHF19,ZFYVE16,ZNF804A,ZEB2,ZBTB24,RHOBTB1,ARNT2,KBTBD11,DLX1,OLIG1,NR1D2,DMTF1,E2F5,E2F6,EBF1,HEYL,KLHL5,PHF20L1,MBNL2,EGR3,PLXNC1,EIF5,COPS4,ING4,EMX2,EN2,OLIG2,ETV1,RTN3,ZIC4,FHL1,FOXG1,FOXF2,FOXM1,FOXO3,ANKFY1,TACC2,PDLIM5,STAMBP,TRIM16,ARFGAP2,TBR1,ABLIM2,ZNF512,ZMAT1,BRPF3,ZMYND11,NKX6-2,SALL3,ZNF274,GBX2,SRCAP,BRD8,ZNF276,DBF4,GLI2,GLYR1,TOX3,ZNF638,INSM2,ATF7,CECR2,STMN2,DIDO1,RFFL,NR3C1,PRDM5,ZNF496,KAT7,ZBTB49,SOX21,ATOH8,MAEL,ZHX1,KLF12,BACH2,HMX1,HNF4G,TLX1,ZDHHC15,HSF2,IRF8,BTBD17,ZNF546,ZIC5,HES5,SCRT2,INSM1,ZNF385B,LIMS1,LMO1,LMO2,SMAD1,SMAD9,ZFYVE27,MBD1,MBNL1,MEF2C,MEIS2,MID1,MITF,AFDN,MXI1,MYCN,MYT1,RCOR2,NEUROD1,NEUROD2,NFIA,NFE2L2,NFIX,NFYA,NHLH1,NKX2-2,CNOT4,CHAMP1,PAX6,PBX1,ZNF655,ZNF426,PRRX1,ING3,POU3F2,POU3F4,POU6F1,IRX1,PPARA,MED1,PROX1,QRICH1,ZIK1,PEX2,ZSCAN2,ROGDI,DBX2,FEZF2,TRIM68,DPF2,RET,RFX2,RFX3,RFX4,ZDHHC4,UBR7,RNF220,PBRM1,ZFHX4,RORB,FBXW7,SOX8,ZNF354C,RXRA,RXRG,SALL1,SATB1,ATXN1,HES6,ZFP2,SOX6,TRIM46,ZNF821,ZFP30,PPP1R9A,ARX,FBXO11,DZIP1,LIMS2,RUFY2,PKNOX2,KDM4D,ZNF334,BTBD7,ZKSCAN3,ZFP1,ZNF667,SMARCA4,SMARCD3,SMARCE1,PDZRN3,KDM4B,SOX1,MYT1L,TRERF1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,KDM3A,ZHX3,SP2,SP4,KDM4C,ZNF423,KIF1B,ZBTB43,RBM26,NPAS3,POGZ,MESP1,JMJD6,SUPT5H,PJA1,TAF6,TAL1,MGRN1,TBX15,TCEA1,TCF4,SIN3B,SATB2,ZFP90,CUX2,TCF7L2,ZEB1,TRIM2,TCF12,NSD1,AKNA,HIF3A,ZFPM2,ZMAT3,ZNF106,THRA,GZF1,HEY1,ZFP91,NR2E1,HEY2,NR2C2,ZNF346,TRPS1,ZMYND8,ZKSCAN5,UBTF,VAV1,NSD2,ZFP37,ZBTB14,ZIC1,ZIC2,ZIC3,ZNF711,ZNF23,ZNF24,TRIM9,ZFP41,ATP6V0E2,NDRG4,MKRN3,SPHK2,ZNF142,ZBTB38,ZBTB16,ZNF184,ZNF189,ZNF213,ZFAND5,MEIS3,PRDM2,EVI5,PRDM8,RNF103,NAV3,RTN4,KAT6A,JMJD1C,ZNF248,ZDHHC20,DPF3,RNF146" Pubmed 16959763 Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Pubmed 1.61E-34 3.70E-29 1.28E-30 1.65E-29 70 138 "ARID1A,GRAMD1B,KCTD16,PPFIA2,KCNAB2,PPFIA3,MADD,MARK4,ATP2B1,ATP2B2,ARHGEF7,CAMK2A,CAMK2B,CAMK2D,CAMK2G,INA,ARHGEF2,CLTC,HOMER3,ARHGEF6,MATR3,RIMS3,AK5,DMTN,EVL,GFAP,GSN,PADI2,IDH3B,DOCK7,ITPKA,KIF2A,KIF5C,MAP2,MAP6,MARK3,MBP,GIT1,MYO5A,NF1,NOS1,PDE1A,PDE1B,PFKP,CAMKV,PLEC,PPP3CA,PPP3CB,PPP3CC,PRKACB,ROGDI,RASGRF2,SBF1,SFPQ,MYO18A,WDR37,SLC1A3,CCDC88A,ERC1,SPTAN1,SYN1,SYN2,CAMSAP2,DMXL2,WDR7,PSD3,SIK3,TUBB2A,CLIP2,TUBA1A" Pubmed 16512683 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. Pubmed 1.16E-33 2.66E-28 8.88E-30 1.15E-28 74 157 "ADD1,ADD2,AP1B1,AMPH,BIN1,VAT1L,BCAS1,PPFIA3,SPTBN4,ATP2B1,ATP2B3,ADGRB1,FUBP1,CALM1,CAMK2A,CAMK2B,CAMK2D,DCLK1,CLTB,NGEF,MATR3,SV2A,DYNC1I1,DPYSL2,PHF20L1,EPB41L2,RTN3,TUBB4A,NCKAP1,PCSK1N,MAP2,MAP6,MBP,NF1,NOS1,PDE1A,PDE1B,PFKP,CAMKV,STRN3,SEPT4,PPP3CA,PPP3CB,DIRAS2,PTPRE,RAB3A,RAP1GAP,ROGDI,RPS20,SARS,SBF1,TRIM46,KIF21A,SH3GL2,WDR37,RPH3A,SIRT2,NAPB,KIF21B,FNBP1,SPTAN1,CLASP2,EPB41L3,SEPT8,SEPT3,STXBP1,ACSBG1,SYN1,SYN2,SYT1,SYT5,TPD52,TPD52L2,RTN4" Pubmed 8125298 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Pubmed 2.10E-33 4.82E-28 1.56E-29 2.01E-28 348 1883 "ACHE,RBM10,ABHD6,AS3MT,ACTN1,ARID1A,ADCY6,ADD3,ADRB2,AP2A2,AGT,SPOP,FAM135A,ANK1,ANXA7,GAS7,DGKZ,APOC1,BCAS1,AQP4,CDC14B,PDXK,ARSE,CDK13,ZSCAN18,ALDH4A1,CHID1,CCDC181,ATP1A2,ATP1A3,EIF4G3,MTMR9,ATP6V0A1,BARD1,BCS1L,PROM1,BTK,RAB29,CALB2,CAMK2B,CAMK2G,CARS,NFS1,LDB2,CCKBR,RGN,SLC16A4,SEPT7,TBRG4,GPR37L1,FOXN3,CHGA,CHGB,CHI3L2,CPNE6,PLAA,CLCN4,TPP1,STOML1,CLTA,FHL5,PICK1,LETMD1,NSL1,CHD1L,CLOCK,CRHBP,CSNK1E,CTH,NRSN1,PUM1,CX3CR1,DCAF8,RASSF2,GIT2,DBN1,TMEM130,WDR20,DNM1,DPYSL2,DTNB,DNAJB6,E2F6,USH1C,ATL1,EEF1D,SH3GLB1,EGFR,KMT5B,AASS,LPAR6,ASB3,EIF4G2,COPS4,TNK2,PCOLCE2,BSCL2,ELN,TMEM35A,PLEKHO1,VPS13B,COQ7,LRRC23,LRRC17,SEZ6,IGSF6,RTN3,ANKMY1,CD320,REEP2,ARMCX1,WAC,TUBB3,DLC1,RACK1,ZMYND10,FCGR3A,KAT8,PPP1R1B,FECH,GTF2IRD2,KIAA1109,FGFR1,BAIAP2,AMOTL2,FHL1,PCYOX1,SYNCRIP,ANKFY1,DCTN2,FOLR2,COQ5,WDR83,ZBED3,USP16,APOPT1,SARAF,DKK3,GABBR1,GABRA1,GABRB1,GALNT15,ZNF274,IP6K3,ERAP1,MTHFD2,GATM,ALDH1L1,GFAP,ADAM28,GGT5,RUNDC3A,BRD8,STARD3,HTATSF1,GNAS,TDRKH,LILRA2,GRK4,TUBA1C,PLCD4,NR3C1,TMEM25,SLC2A6,HBA1,FRMD3,DDX19B,HSF2,HSPA1L,SMAP1,IDH3A,TJAP1,IGSF1,IL6R,LRRTM1,ITIH2,KCNJ16,KHK,IPO5,MAG,MATK,MBD1,TM6SF1,MDM4,MOV10,MPP2,N6AMT1,MTTP,SAMD14,MX1,NACA,NAP1L3,NASP,DDR2,NUCB1,GPR88,OMG,P2RX7,ZNF827,PCSK5,PDPK1,OLA1,GDAP1L1,SERPINE2,NOMO2,PIK3R1,ZNF655,RETREG1,PKM,KCTD15,PLTP,MTRF1L,RC3H2,PRRX1,PTPA,NKAIN4,PPP5C,MAPK10,DCHS2,NDUFS7,SAMD9,BCAS3,SLC22A23,CYBC1,LRRC49,SYTL2,GON4L,PSMD13,PLPPR1,PEX5,PPP2R3C,QDPR,CEP97,USP47,PLEKHB2,HKR1,BSDC1,GAL3ST4,PRRT2,RFX5,ZDHHC4,RGS3,TTLL7,RNF220,C12orf49,ALG9,CARF,GSTCD,YY1AP1,ELP2,CCDC102B,FBXW7,ZNF671,ATAT1,NCBP3,DGLUCY,FOXRED2,SARS,TRIM46,SELL,ASRGL1,SUPT20H,COPZ1,SH3BP2,PPP1R9A,FERMT1,SHMT2,FBXO11,CCDC92,SEC31A,PAAF1,CLSTN1,ABLIM3,SMTN,WDR47,SIRT2,CDK5RAP3,MTERF2,ARFGAP1,NAXD,OGDHL,INTS9,IFT122,SNAP25,KIF13A,LMBRD1,SNRPN,USP33,SOX5,SPATA7,ZC4H2,NSFL1C,TAC1,POPDC3,MMS19,ROBO3,TCF7L2,PCDHB7,CYB561A3,TF,TGFBR3,AKTIP,TIE1,HEY1,ACTR6,TPD52,TPD52L2,TPM2,SMUG1,ELP5,PDSS1,NEIL2,AMACR,TRO,ZMYND8,KCNE5,TSN,TST,TMEFF2,SGK3,UGT8,MTCH1,PLPPR2,VAV1,VGF,MEAF6,MICAL1,TBC1D15,LMF1,LAT2,NPDC1,CFAP298,ZNF225,INTS3,PRTFDC1,DNALI1,SLC38A1,STMN4,LMAN2L,ITM2C,PCBP4,MPPE1,PDSS2,PHTF2,RNF170,AAAS,FXR1,LAS1L" Pubmed 15302935 Large-scale characterization of HeLa cell nuclear phosphoproteins. Pubmed 3.48E-33 7.98E-28 2.50E-29 3.22E-28 188 773 "ABCF1,ACLY,RBM10,GPRIN1,ADCY6,ADD1,ESYT2,TAOK1,MRTFA,ZNF687,BIN1,EP400,PHF12,PARG,MIER1,CDK13,ASPH,CCAR2,ATM,ATP2A2,BACH1,BLM,FUBP1,CAST,SPAG9,CBFA2T2,CDK11B,ARHGEF2,ZMYM4,LRRFIP1,CDO1,LRWD1,EPS15L1,CLTC,TJP2,MAP4K4,NIPBL,ARHGEF6,IQCK,NCOR1,NCOR2,SEC24C,CSNK1E,SIPA1L1,APPL1,PHF14,GAPVD1,MATR3,DBN1,YTHDC1,MED24,ZC3H11A,DDX46,SEC16A,DNM2,ATN1,PHC2,FAM13A,SUGP2,EGFR,EIF4G1,EIF4G2,SORBS3,EPB41L2,SRRM1,SCML2,UBE2E3,FOXM1,EVL,USP16,TRIM16,OGA,STAG2,RAPGEF6,SEPT9,USP19,BRD8,RNPS1,DBF4,MSL3,ZNF638,KIAA1958,KDM2B,EML4,DIDO1,RFFL,CLASRP,PSIP1,ZHX1,ATXN2L,HNRNPK,IFI16,TJAP1,PAXBP1,MAP4,MAPT,MATK,AFF1,AFDN,MN1,GIT1,MYCN,NASP,NF1,NFIA,NUMA1,ODF2,CHAMP1,PDPK1,PFKP,SSH1,ANLN,PLEC,STRN3,MED1,KANSL1,PKN2,MAPK3,MAPK8,RIPOR1,USP47,ARID4A,RBBP6,RBBP8,DPF2,YY1AP1,CLIP1,SAFB,ATXN7,SCAF8,ITSN1,MYO18A,URGCP,PPP4R3A,SMTN,KANSL3,ARFGAP1,SMARCA4,SMARCC2,LIMCH1,RIMS1,FAM126B,KDM4B,SON,TRERF1,FNBP1,KDM3A,ZHX3,MYCBP2,ZC3H13,SPTAN1,KIF1B,POGZ,ITPRID2,ERBIN,MAPK8IP3,GSE1,NSFL1C,ZC3H4,TAF6,DNMBP,UNC5D,AGTPBP1,TCEA1,ZEB1,CLASP1,PUM2,SIRT1,ZNF106,ZFP91,TMPO,PARD3,KAT6B,TP53BP1,TPM3,ZMYND8,KLC2,RICTOR,XPO1,SF1,TFIP11,SMARCAD1,INTS3,EMSY,PRDM2,FIP1L1,NELFE,NUP214" Pubmed 26638075 A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Pubmed 1.66E-32 3.80E-27 1.15E-28 1.49E-27 337 1820 "RALGAPA1,ASIC1,C3orf14,XKR4,ADD1,ADD3,SNX30,ESYT2,KIDINS220,AP2A1,AP1B1,MTUS1,RTL9,OSBPL8,TXNDC16,CC2D2A,AK2,SEMA6A,MRTFA,OGT,ANK2,ANK3,PKP4,APBB1,APC,EPB41L5,CACHD1,TNRC6C,APP,CASK,ARRB2,ASPH,NUMB,CCAR2,DDX3Y,DYNLL1,CHID1,ATP1A1,ATP1A2,STX16,ATP2A2,ATP2B1,DPY19L3,ATP6V0A1,KIF1A,SEC11C,BLM,DST,BSN,BTRC,CFAP410,CACNA1A,CALM1,CAMK2B,CAMK2D,TRIM41,CANX,MAP7,PRC1,INA,AIFM1,SCARB1,LRBA,ARHGEF2,DCLK1,CLGN,COPB2,CBARP,CLTC,TJP2,FADS2,HECTD1,MAP4K4,BTF3L4,AKAP5,SLC4A7,MAGED1,RTTN,FAM171B,AKAP12,NCOR1,SEC24C,CSNK1E,SIPA1L1,APPL1,CTNND1,USP6NL,TBC1D5,LIN54,MATR3,KIAA0586,DAPK3,DBT,SPATA2,DCTN1,MYEF2,KIAA0753,CEP170,SMG7,WDR20,SEC16A,CD99L2,DNM2,SLC12A6,DTNB,DNAJB6,ABCC5,GOLT1B,SH3GLB1,SUGP2,COPS4,TENM1,PLEKHA1,EML1,DCTN4,ENO2,MFSD10,EPB41L1,CEP85L,RTN3,REEP2,TUBA1B,TUBB4A,GORAB,SEC24B,BAIAP2,CAMSAP1,SEC23B,FOXO3,DCTN2,WDR83,NBEA,SORBS1,SMC2,PDLIM5,ARFGAP2,ATP2C1,ERGIC3,PNMA2,AP4B1,OGA,NEURL4,GAB1,HBS1L,AHCYL1,RAPGEF6,NCKAP1,TUBA8,ARFIP1,WASHC2A,TOX3,TNRC6A,HTATSF1,MAP7D2,OS9,DCLK2,GNAO1,FERMT2,PRRC2B,EML4,TUBA1C,CNTRL,NR3C1,GRM5,KIF3A,AP4S1,RASSF8,PACSIN2,DDX19B,KLF12,HMGCR,AGFG1,DHX35,HSPA1L,HSP90AA1,FAAP20,IDH3B,LRRCC1,USP54,TUBB2B,KIF2A,KLC1,IPO5,KTN1,MAP2,MAPT,LYPLAL1,MARK3,POC1B,MTR,MYO9A,NACA,HNRNPM,NAP1L1,NDUFA5,NEK1,PCBP3,SLC11A2,NUCB2,NUMA1,OCRL,ODF2,PALM,PIK3C2A,ANLN,PIK3R1,CCSER2,RETREG1,XRN1,EPN1,C11orf49,MBOAT7,FA2H,SH3KBP1,FSD1,PPP2R2B,CEP41,PKN2,MAPK9,CNNM2,BCAS3,LRRC49,PTPN13,OCIAD1,TTC13,PPP2R3C,RAB5B,CEP97,BSDC1,SLC6A15,KIF7,RNH1,ALG9,KIRREL1,ZC3H14,WLS,CLIP1,NCBP3,CCDC112,SCN3A,TRA2B,COPZ1,HSPA4L,FNDC3A,CCDC92,SEC31A,SLC1A3,EPN2,DHX30,SLC6A8,SLC6A9,RAB3GAP1,SIRT2,SLC12A2,SLC12A4,SLC20A2,GKAP1,CDK5RAP2,INTS9,RCOR3,LIMCH1,PALLD,PDZRN3,FAM219A,TNIK,FNBP1,ZSWIM8,CLUAP1,EMC1,TEX2,ERC1,UNC5B,KIF1B,SPART,TAB2,CLASP2,ERBIN,MPRIP,STAU1,NEK4,GANAB,GSE1,SUPT5H,ANKRD28,DNMBP,CAMSAP2,FAM208A,AGTPBP1,TBCEL,FBXW11,EHBP1,TRIM2,RPGRIP1L,WASHC4,USP22,CLASP1,DICER1,SIRT1,AP4E1,AKTIP,TMEM9,TJP1,TMPO,PARD3,TP53BP2,RBFOX2,METTL3,TRIO,STXBP4,HSPBP1,TUBB2A,EIF4ENIF1,AMOT,UGT8,CCDC14,TBC1D15,KLC2,TRIM9,TMEM237,SH3GLB2,FTSJ1,TFIP11,SMARCAD1,EMSY,LRP8,SLC38A1,TUBA1A,SNX27,ITM2C,GOPC,ST7,RTN4,VANGL2,ZDHHC20,AAAS,IFT88,NETO2" Pubmed 11230166 Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Pubmed 1.46E-30 3.36E-25 9.88E-27 1.28E-25 179 750 "RBM10,NDRG2,KIAA1211,AP2A1,INTS2,ADGRF5,FAM135A,SYT13,BIN1,C6orf89,GPAM,USP37,CCAR2,TMEM108,NAE1,GPC2,BAIAP3,ZNF555,CAST,ENTPD6,ARHGEF2,SYNPR,CNOT8,PPT2,CLCN3,SOCS5,PNPLA8,ARHGAP24,AIF1L,DBN1,ELMO1,FBXL5,TMEM130,SV2A,FAM107B,CCDC3,ARNT2,RAB39B,CD99L2,FAM57B,ECM2,DNAJB6,GOLT1B,AASDH,FCF1,EIF5,MRNIP,ELN,EMX2,COQ7,EPHA5,NCALD,ADGRV1,CD320,NSRP1,FAM198B,ZMYND10,TOMM40L,MEX3B,HPCAL4,RGPD5,IQCG,ZMYND15,PSD2,SGIP1,SLC37A3,FLYWCH1,SYT3,JKAMP,SORBS1,PDLIM5,MSANTD4,MPP6,PHYHIPL,GALNT15,BRD8,SPIN1,GPM6B,NUDT21,ADAMTS13,FAM107A,PACSIN2,DDX19B,MIER3,ELOVL5,SYNPO,OPALIN,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MITF,MMP16,MOV10,MPP2,MRPL42,MYBPC1,FXYD6,SNTG1,PCSK5,GPR85,OLA1,ABCB1,CAMKV,C11orf49,PDZRN4,CDIP1,RETREG2,PACSIN1,KANSL1,GON4L,ANKHD1,MTMR10,RAB5B,RAD17,FAM184A,ZCWPW1,ROGDI,TRIM68,ZDHHC4,ALG9,PNMA8A,YY1AP1,PLPPR3,KCNIP2,FAM192A,AP1AR,DGLUCY,FAM19A1,SEC14L1,SOX6,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,RADIL,ELMO2,LIMCH1,SCN3B,SPATA7,ZC3H13,TSPYL2,POGZ,STAU1,SEPT3,KLHL7,SYNE2,TCF12,SLC35G2,SIRT1,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,SSBP2,PLEKHH2,USP1,KLC2,NDRG4,SPHK2,TFIP11,CA10,RGMA,STMN4,LMAN2L,CIAPIN1,VPS35L,FIP1L1,ITM2C,PHTF2,TIGD6,RNF170,SSPN,RNF146,SENP7" Pubmed 11076863 DNA cloning using in vitro site-specific recombination. Pubmed 1.10E-29 2.53E-24 7.24E-26 9.35E-25 184 794 "RBM10,TKTL1,NDRG2,ADCY8,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,APC,GPAM,APOC1,USP37,CDK10,CCAR2,HCN2,PROM1,C1QC,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,SYNPR,CNOT8,JAM2,PPT2,CLCN3,FBXO7,TJP2,PNKD,MROH8,LRRC3B,NCAN,PNPLA8,CTNND2,USP6NL,NOS1AP,AIF1L,DBN1,FBXL5,TMEM130,SV2A,FAM107B,CCDC3,ARNT2,RAB39B,DMD,CD99L2,FAM57B,ECM2,DNAJB6,MRNIP,ELN,PLEKHO1,COQ7,EPHA5,NCALD,F5,NSRP1,FAM198B,RACK1,ZMYND10,TOMM40L,MEX3B,HPCAL4,PSD2,SGIP1,SYT3,JKAMP,SORBS1,PDLIM5,CSPG5,KBTBD12,MSANTD4,PHYHIPL,GALNT15,GAP43,SPIN1,GPM6B,CCDC184,NUDT21,GRM1,IL1RAPL1,SOX21,FAM107A,MIER3,GABARAPL2,SYNPO,OPALIN,HSPA1L,ICA1,IGSF1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,ADAM11,MIA2,SCAMP5,MOV10,MYBPC1,FXYD6,NDP,SNTG1,PCSK5,GPR85,ABCB1,C11orf49,PACSIN1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAB5B,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,KCNIP2,FAM192A,AP1AR,DGLUCY,FAM19A1,SEC14L1,SOX6,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SCN3B,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,TLL2,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,VAV2,KLC2,ZIC3,NDRG4,TFIP11,RGMA,CSDE1,LMAN2L,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,SSPN,FXR1,RNF146,SENP7" Pubmed 16284245 Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Pubmed 1.47E-29 3.38E-24 9.40E-26 1.21E-24 61 123 "UNC5A,SEMA6A,SEMA7A,SEMA4G,PTCH2,CALB1,CALB2,LDB2,CDH8,CDH10,SLIT2,LHX2,CRYM,PLXNA4,BOC,DCC,ARNT2,CDON,SEMA3D,PLXNC1,EMX2,EPHA5,ETV1,FGFR1,FGFR3,FOXG1,SEMA4D,TBR1,DKK3,GAD1,NTNG2,LIX1,SYT9,KITLG,NEFH,NEUROD1,NKX2-2,PAX6,SERPINE2,SEMA5B,PLXNB3,RELN,PTCH1,PTN,FEZF2,ROBO1,ROBO2,RORB,SEMA6D,NTNG1,SLIT1,SOX2,SOX5,UNC5B,ROBO3,UNC5D,CDH22,SEMA3B,TMEM163,NETO2,NETO1" Pubmed 16985003 Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Pubmed 5.01E-29 1.15E-23 3.11E-25 4.02E-24 64 137 "KCNH8,KCNAB2,ATP1A2,ATP2A2,HCN2,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,P2RX6,KCNAB3,CACNA2D2,CLCN3,CLCN4,ABCC9,KCNMB2,CACNG2,KCNMB4,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN3,KCNQ2,KCNQ3,HCN1,P2RX7,KCNIP3,KCNIP2,KCNIP1,SCN3A,SCN7A,SCN8A,SLC8A1,SCN3B,ABCC8,KCNK12,KCNAB1" Pubmed 11125038 Database resources of the National Center for Biotechnology Information. Pubmed 3.36E-28 7.72E-23 2.03E-24 2.62E-23 297 1614 "KCNH8,CCDC85A,HHATL,ESYT2,CASKIN1,SORCS2,DISP3,TXNDC16,CC2D2A,C1QTNF3,C1QTNF4,ZNF687,PITPNM2,CNIH2,PPFIA1,NT5C3B,FAM131A,LRRC4C,SHTN1,CDC14B,MIER1,SEMA4G,ARHGDIA,ARHGDIG,CHID1,CADM3,N4BP2L1,KIF1A,DOCK11,CARMIL3,LDHD,JAZF1,NIPA1,CA12,KALRN,METTL6,SYNGR3,MAGI1,UBE2L6,DIS3L,CHN1,CHN2,EPS15L1,TMEM59L,FBXO7,QKI,CCDC151,ARMC8,LETMD1,ACBD5,MFSD4A,FAM171B,CLIP3,SIPA1L1,RASGEF1C,APPL1,FGFR1OP2,GAPVD1,ARHGAP24,TBC1D5,LIN54,KIAA0586,INTS1,MAML1,ARMCX2,YTHDC1,ZNF804A,CNIH3,HP1BP3,KIAA0753,SV2B,CCDC3,EXOG,NYAP1,RPS6KL1,FAM57B,FCF1,KLHL5,EBI3,MBNL2,SORBS3,ELAVL3,C3orf18,TMEM35A,STARD3NL,ANKRD13B,CD320,ECSIT,ARMCX1,CLVS1,FAM198B,WAC,ZIC4,CEP78,KAT8,MAD2L2,SCARA3,ATP5PD,IQCG,SGIP1,DCTN2,TMEM175,EFCAB2,WDR83,JKAMP,AK8,FAM49B,ARFGAP2,ST6GALNAC3,MSANTD4,SARAF,ZNF512,PHYHIPL,DENND2A,HIGD1B,KIAA1841,FAXC,MMADHC,ZNF276,RND1,RNPS1,RAB30,KDM2B,OS9,PRUNE2,ATF7,ADAP1,EML4,PRDM5,ZBTB49,RABL2A,MAEL,RASSF8,FRMD3,ARHGAP19,NCKAP1L,ARHGAP36,ZDHHC15,LRRCC1,DISP2,USP54,ZNF385B,SLC35G1,GATD1,HECTD2,ARHGAP12,LYPLAL1,SYT9,KCTD6,BLOC1S2,RSPO2,HS6ST3,NAP1L3,NKX2-2,TBC1D25,ANLN,ZFYVE21,XRN1,FAM216A,FTO,EPN1,ZNF426,SPATA6,MINDY2,CEP41,RAB39A,GDPD1,LRRC49,GDPD2,QRICH1,CNTLN,PLPPR1,PXK,SPDL1,TMEM260,ZIK1,PEX5,RIPOR1,ZSCAN2,MARCH1,SUSD4,RADX,VEPH1,KHDRBS2,ERI2,GTDC1,PRIMA1,ARHGEF10L,SLC25A36,ZFHX4,KLHDC8A,CYB561D1,CCDC25,ELP2,TMEM100,NEK11,UEVLD,GLDN,TCP11L1,EMID1,FAM161B,ST6GALNAC6,WLS,TRAPPC13,FAM192A,RMI1,DGLUCY,ZNF821,TRA2B,HSPA4L,PUF60,SH3BP2,KIF21A,FERMT1,FUZ,CHD9,SYBU,NUBPL,WDR37,ZNF365,FAM81A,SLC1A7,PPP4R3A,EPN2,FAM214B,KBTBD4,MTERF2,SORCS3,CABCOCO1,PDZRN3,KDM4B,FAM219A,EMC1,ZBTB43,LHPP,PBLD,POGZ,FCHO1,NCDN,KLHL7,DNAJC9,COBL,TAC3,SEMA4A,ROBO3,EXOC7,PDLIM2,KIAA1107,TBCEL,IQCE,EHBP1,PHF24,PCDHB7,PCDHB6,VWCE,ATP13A2,C18orf54,CDH22,FBXL16,MTMR14,NACC2,BHLHB9,ERCC6L2,RIMBP2,PPIL6,FNDC5,CA14,RFTN2,HEPACAM,FRRS1L,PDIA2,FAM181B,PLEKHH2,TBC1D15,LMF1,PCDH20,ZNF23,ZFP41,TCEAL7,ZBTB38,FSTL5,ZNF189,SPIRE1,PLPPR5,INTS3,EMSY,CADM2,DNALI1,TMEM178A,PPP1R3F,TMEM163,FAM13C,UBE3B,PHTF2,FBXO36,SNX14,CBLN2" Pubmed 16381901 The LIFEdb database in 2006. Pubmed 5.04E-28 1.16E-22 2.97E-24 3.84E-23 169 720 "RBM10,TKTL1,NDRG2,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,GPAM,APOC1,USP37,CDK10,CCAR2,PROM1,C1QC,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,SYNPR,CNOT8,JAM2,PPT2,CLCN3,FBXO7,TJP2,PNKD,MROH8,LRRC3B,PNPLA8,USP6NL,AIF1L,DBN1,FBXL5,TMEM130,SV2A,FAM107B,CCDC3,ARNT2,RAB39B,CD99L2,FAM57B,ECM2,DNAJB6,MRNIP,ELN,PLEKHO1,COQ7,EPHA5,NCALD,NSRP1,FAM198B,RACK1,ZMYND10,TOMM40L,MEX3B,HPCAL4,PSD2,SGIP1,SYT3,JKAMP,SORBS1,PDLIM5,KBTBD12,MSANTD4,PHYHIPL,GALNT15,GAP43,SPIN1,GPM6B,CCDC184,NUDT21,FAM107A,MIER3,GABARAPL2,SYNPO,OPALIN,HSPA1L,ICA1,IGSF1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MOV10,MYBPC1,FXYD6,NDP,SNTG1,PCSK5,GPR85,ABCB1,C11orf49,PACSIN1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAB5B,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,KCNIP2,FAM192A,AP1AR,DGLUCY,FAM19A1,SEC14L1,SOX6,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SCN3B,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,VAV2,KLC2,NDRG4,TFIP11,RGMA,CSDE1,LMAN2L,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,SSPN,FXR1,RNF146,SENP7" Pubmed 15489336 From ORFeome to biology: a functional genomics pipeline. Pubmed 7.07E-28 1.62E-22 4.02E-24 5.19E-23 169 722 "RBM10,TKTL1,NDRG2,INTS2,ADGRF5,SPOP,FAM135A,GPRASP2,SYT13,BIN1,C6orf89,GPAM,APOC1,USP37,CDK10,CCAR2,PROM1,C1QC,GPC2,BAIAP3,ZNF555,CAMK2B,CAST,ENTPD6,ARHGEF2,SYNPR,CNOT8,JAM2,PPT2,CLCN3,FBXO7,TJP2,PNKD,MROH8,LRRC3B,PNPLA8,USP6NL,AIF1L,DBN1,FBXL5,TMEM130,SV2A,FAM107B,CCDC3,ARNT2,RAB39B,CD99L2,FAM57B,ECM2,DNAJB6,MRNIP,ELN,PLEKHO1,COQ7,EPHA5,NCALD,NSRP1,FAM198B,RACK1,ZMYND10,TOMM40L,MEX3B,HPCAL4,PSD2,SGIP1,SYT3,JKAMP,SORBS1,PDLIM5,KBTBD12,MSANTD4,PHYHIPL,GALNT15,GAP43,SPIN1,GPM6B,CCDC184,NUDT21,FAM107A,MIER3,GABARAPL2,SYNPO,OPALIN,HSPA1L,ICA1,IGSF1,KHK,STMN1,NCOA7,PIK3AP1,GPR155,MIA2,SCAMP5,MOV10,MYBPC1,FXYD6,NDP,SNTG1,PCSK5,GPR85,ABCB1,C11orf49,PACSIN1,PPP3CA,KANSL1,PRKACB,MTMR10,PTN,QDPR,RAB5B,RAD17,C1orf54,ROGDI,TRIM68,NUDT11,TMLHE,ALG9,PNMA8A,YY1AP1,KCNIP2,FAM192A,AP1AR,DGLUCY,FAM19A1,SEC14L1,SOX6,STUM,FOXRED1,WDR37,ABLIM3,FAM214B,KANSL3,ELMO2,LIMCH1,SNAP25,SCN3B,SPATA7,SPP1,DBNDD2,TSPYL2,POGZ,SEPT3,IQCE,TCF12,SLC35G2,ZNF34,TMEM9,ZNF346,SYNPO2,NEIL2,AMACR,PLEKHH2,USP1,VAV2,KLC2,NDRG4,TFIP11,RGMA,CSDE1,LMAN2L,CIAPIN1,FIP1L1,RTN4,PHTF2,TIGD6,SSPN,FXR1,RNF146,SENP7" Pubmed 26972000 Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways. Pubmed 7.17E-28 1.65E-22 4.02E-24 5.19E-23 283 1517 "SDE2,ACLY,BRAP,CDC7,ESYT2,KIDINS220,CASKIN1,HACE1,OSBPL1A,OSBPL6,OSBPL8,AK2,PLA2G6,FAM135A,GPRASP2,OGT,LRCH2,ANK2,ANK3,PPFIA1,PARG,APBB1,APC,CACHD1,MADD,TMEM263,ZBTB10,NUMB,CCAR2,DYNLL1,ATP1A1,ATP1B3,STX16,ATP2A2,RIPK1,BACH1,BLM,KSR1,NAE1,MTMR3,BTRC,FOXK1,CFAP410,CAMK2D,CANX,CBS,CCNT1,AIFM1,LRBA,CDC27,CDC42,CDO1,TAOK2,ZFYVE9,PLAA,TPP1,HECTD1,MAP4K4,CNN3,ARMC8,MAGED1,IFFO1,ACBD5,CHD1L,PNKD,CREB5,AKAP12,ANKRD44,NCOR1,NCOR2,CS,FEZ2,CSNK1E,OSBPL3,PLXNA4,CTNND1,PUM1,PPP6R2,ARHGAP32,KATNAL2,GAPVD1,TCAF1,DCAF8,ZFYVE16,EARS2,KIAA0586,MAML1,TOMM20,DBN1,DCTN1,CEP170,SMG7,SEC16A,DNM2,TOM1,DUSP9,DNAJB6,DYRK1A,FEM1B,KCTD3,DCTN4,GPHN,DENND4A,MRPL37,TUBA1B,TUBB3,TUBB4A,CEP78,FDFT1,PRMT5,FECH,SEC24B,POLR1B,CAMSAP1,ATP5PD,SEC23B,FOXO3,ANKFY1,DCTN2,COQ5,SMC2,ARFGAP2,ATP6V1H,MPP6,NEURL4,GAB1,HBS1L,FAM120B,INPP5K,GART,GFER,GLI2,GLUL,MAP7D2,OS9,GNAS,PRRC2B,TUBA1C,HNRNPK,HSP90AA1,IDH3B,DOCK7,TJAP1,USP54,TUBB2B,KIF2A,KLC1,IPO5,MKLN1,DBNL,MSI1,PTOV1,MTR,MYO6,NACA,NAP1L1,NASP,NDUFA5,NRDC,NUCB1,OCRL,OPA1,PDCD2,PRTG,PDE3B,CDK14,PIK3C2A,PIK3R1,CCSER2,XRN1,KCTD15,MAPKAP1,PPM1B,PPP5C,PRKAR1B,RAB39A,NDUFS7,QRICH1,PSMD13,ANKHD1,PTPN13,OCIAD1,C1orf109,TTC13,CEP97,USP47,RADX,MORC4,UBR7,KIF7,RNASEL,RNH1,EXD2,ARMC5,RAVER2,ROBO1,ELP2,MCMBP,RTKN,RMI1,FOXRED2,SARS,SBF1,ATXN2,COPZ1,HSPA4L,SCAF8,CPEB3,AMBRA1,PAAF1,SMTN,RADIL,RAB3GAP1,CCDC88A,CPEB4,CDK5RAP2,TTC17,PDZRN3,ZSWIM8,MYCBP2,SPART,TAB2,TROVE2,ERBIN,NCDN,PHLDB1,GANAB,FAM168A,SYNE2,ANKRD28,MMS19,MTCL1,PJA1,MLST8,TAF9,EXOC7,CAMSAP2,ALG1,FBXW11,TBL1X,MGRN1,TCF4,DMXL2,TCF12,WDR7,OBSL1,SIK3,DICER1,SIRT1,ZFPM2,ZNF106,MTMR14,DDHD1,TMPO,R3HDM1,PARD3,RBFOX2,TPD52,STXBP4,TSC2,HSPBP1,TUBB2A,TUBB1,UBC,EIF4ENIF1,UBE3A,AMOT,GORASP1,SLAIN1,MTCH1,TBC1D15,RICTOR,XPO1,ZIC2,ZNF24,MFF,CIAPIN1,GOPC,RTN4,JMJD1C,NHSL1,AAAS,LAS1L" Pubmed 16189514 Towards a proteome-scale map of the human protein-protein interaction network. Pubmed 1.11E-27 2.55E-22 6.06E-24 7.83E-23 290 1573 "RBM10,ACTN1,FZD9,AGT,NME5,C1QTNF1,SPOP,BEGAIN,KIF6,OGT,PPFIA1,UPRT,SEMA4G,ARRB1,ASPA,RASL11B,MTMR9,NOL4,ADAM15,BBS2,CDK5R1,AP1M1,GYG2,BTRC,LURAP1,CALM1,PTBP2,TRIM41,CAPN3,RUNX1T1,PRC1,CBS,CCNH,USP2,CBFA2T2,ZBED1,CDC42,EVI5L,CFL2,RCBTB2,CNOT8,SLC22A6,RAB33A,FAM189A2,QKI,HOMER3,FHL5,CNTFR,IFFO1,PNKD,HINFP,TRIM69,SEC24C,CSNK1E,APPL1,CTH,GPSM1,KIAA0408,TCAF1,DCAF8,ZNF337,TBC1D5,MATR3,IST1,IP6K1,SIRPA,PITPNC1,SPATA2,JAKMIP2,ZBTB24,BLOC1S6,ZC3H11A,POM121,PARD6A,DYNC1I1,DTNB,ABCC9,E2F6,PHC2,HEYL,EEF1D,OPTN,EBI3,ABI2,SORBS3,COPS4,ELAVL3,ELAVL4,BSCL2,EML1,HSD17B14,EPS8,NCALD,EFS,RTN3,KATNAL1,WAC,SH3YL1,EFEMP1,RACK1,ZMYND10,BAIAP2,AMOTL2,HPCAL4,SEC23B,IP6K2,VTI1B,DCTN2,C2orf88,ZCCHC17,CINP,PDLIM5,STAMBP,KHDRBS3,SDCBP2,PHYHIPL,TRAF3IP2,GAD1,FAM120B,NEK6,ZNF559,SYT17,INPP5K,MYOZ2,TUBGCP4,GFAP,RUNDC3A,NTNG2,ZNF276,TXNL4A,RNPS1,GLUL,ZNF638,POLL,LNX1,PRRC2B,PRUNE2,NUDT21,STMN2,DIDO1,PLCD4,SERP2,ANKRD36BP1,ZNF496,CLASRP,KAT7,LINGO1,FAM107A,GYG1,RASSF8,C1orf94,PACSIN2,KLF12,GABARAPL2,HNRNPK,ITPKB,LIMS1,LMO2,SYTL4,SMAD9,MARK3,MATK,MDFI,DBNL,MXI1,HNRNPM,NASP,NDUFA5,NFYA,NME4,OGDH,PCSK5,CDK18,ZNF655,NLE1,ZNF426,C11orf49,MAPKAP1,NECAB2,PACSIN1,C19orf57,PPARA,PPP3CA,KANSL1,PRKCZ,MAPK9,PRPH,WDR25,PTK2,ZSCAN32,PEX5,RAB3IL1,RAP1GDS1,ENOX1,BEND5,RBBP8,KHDRBS2,RFX2,RFX3,RGR,KCTD17,SETD5,CARF,YY1AP1,RPE,SNX22,BAALC,ZC3H14,MCMBP,KCNIP3,RTN1,RXRG,CCDC112,S100B,SATB1,ELMOD1,ZNF821,PUF60,DOCK10,FUZ,WDR37,PEX26,FAM214B,SEPHS1,RADIL,ZNF334,GKAP1,RCOR3,SNAP25,DOK5,CLUAP1,SPP1,DBNDD2,ZBTB43,LMO3,SRPK2,PBLD,EPB41L3,ZC4H2,NXT2,GSE1,SYT11,ARC,SYT4,TAF9,EXOC7,NEU4,TRIM2,RALYL,ARHGAP9,FRYL,C18orf54,ITGB3BP,AKTIP,CBX5,HEY2,FAM124A,TNNT1,RBFOX2,TPM1,TPM3,PRMT8,SMUG1,SSBP2,HSPBP1,UBC,EIF4ENIF1,BCL2L13,MEAF6,CCDC14,VSNL1,NPDC1,XRCC4,SF1,ZNF24,TRIM9,ZBTB16,SH3GLB2,PRTFDC1,CIAPIN1,NAV2,FIP1L1,ITM2C,PLSCR4,PARP11,GOPC,FAM13C,RTN4,PAK5,FRMD6" Pubmed 24722188 Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Pubmed 2.36E-27 5.43E-22 1.26E-23 1.63E-22 115 400 "ABAT,DGCR6,GALNT13,ADORA2A,PTCHD1,ADRB2,CEP126,PCDH10,GPRASP2,MRTFA,DOC2A,LCORL,PPFIA1,CASK,ARNTL,RGS20,NOL4,KIF1A,NRP2,CACNA1G,CAMK2B,ZBED1,CDH10,LARGE1,DLGAP2,RCBTB2,TAOK2,MAGED1,RCHY1,IFFO1,CHD1L,CRMP1,PDE4DIP,CNTNAP2,CMTM5,RIMS3,ZEB2,BLOC1S6,ZC3H11A,ARNT2,DLG2,DLX1,DMPK,DPYSL2,SEZ6L2,SORBS3,ERBB2,EFS,WAC,FGFR3,GABRA4,GABRB1,GABRB3,DISC1,CPLX1,TUBGCP4,LNX1,RAPGEF4,C1orf94,KLF12,INPP1,KIFC3,MARK1,MDFI,MEIS2,MIA2,NTRK3,OXTR,PCDH9,PDE4B,NLGN3,NECAB2,PRKAB2,MAPK3,PRODH,MTMR10,PYGM,RAP1GDS1,BEND5,CCDC102B,RPS6KA2,NTNG1,NUBPL,SLC6A8,NAPB,GKAP1,SNRPN,SP4,NPAS3,ZC4H2,CEP68,STX1A,GSE1,FAM168A,IQCE,TCF4,TCF12,TNS2,TP53BP2,TSC1,TSC2,CADM1,EIF4ENIF1,UBE2H,UBE3A,AMOT,MGAT5B,CCDC136,VIPR2,AGMO,MKRN3,TFIP11,GOPC,DOCK8,ST7" Pubmed 29031500 Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Pubmed 2.63E-27 6.03E-22 1.37E-23 1.77E-22 86 246 "SLITRK1,SEMA6A,ALK,SEMA4G,ARNTL,ASCL1,NRP2,BMP7,JAZF1,CALB1,SLIT2,SLITRK5,ZEB2,ARNT2,DLX1,EBF1,EDN1,EDN3,EDNRB,SEMA3D,EFNB3,CELSR3,ELAVL3,ELAVL4,EPHA5,ETV1,FGF1,FGF13,FGFR1,FOXO3,SEMA4D,CSPG5,GFRA1,GFRA2,HLF,HMX1,IGF1,L1CAM,MEF2C,MEIS2,MYCN,MYT1,NOS1,NPY,NRCAM,NTRK2,NTRK3,PLXNB1,PTCH1,PTN,ZIK1,PTPRN,PTPRO,PTPRZ1,RET,ZFHX4,ROBO2,SOX8,RXRA,RXRG,SEMA6D,SATB1,SOX6,NTNG1,SLITRK3,SLIT1,MYT1L,SOX2,SOX5,SOX10,SOX11,ZHX3,UNC5D,TCF4,SATB2,CUX2,TCF7L2,ZEB1,TCF12,FLRT2,FLRT1,ZNF24,ZNF184,LRP8,SEMA3B,FZD3" Pubmed 27173435 An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Pubmed 4.65E-27 1.07E-21 2.38E-23 3.07E-22 254 1321 "ABCF1,ACTN1,FMNL2,ADCY6,CDC7,AP2A1,AP2A2,RTL9,OSBPL1A,OSBPL6,WDR35,AMPD2,LRFN1,OGT,LRCH2,ANK3,ARHGDIA,ARNTL,DACT3,NUMB,CCAR2,DYNLL1,ATP2B2,BACH1,BBS2,BLM,KSR1,WASF1,FOXK1,CFAP410,CALM1,CAMK2A,CAMK2B,SPAG9,MAP7,CBS,SEPT7,CDC25B,CDC27,DCLK1,LARGE1,MAGI1,CLGN,NUMBL,SLIT2,EPS15L1,RAB28,NRXN1,MYL6B,CLTA,CLTB,TMEM184B,ARHGEF6,ARMC8,WHRN,IFFO1,CLOCK,AKAP12,CS,OSBPL3,SIPA1L1,DZIP3,APPL1,EDRF1,CCDC144A,GAPVD1,HDAC4,MAML1,GIT2,DCTN1,CEP170,POM121,RABGAP1L,WDR20,SEC16A,TRAPPC9,DNM2,ABI1,DYRK1A,E2F5,USH1C,SH3GLB1,KCTD3,COPS4,STARD3NL,C8orf37,PAN3,DCTN4,GPHN,DENND4A,DUSP27,ECSIT,ZMYND10,TESK2,FECH,SEC24B,BAIAP2,ATP5PD,VTI1B,SYNCRIP,AGAP3,FOXO3,DCTN2,WDR83,SMC2,UFM1,USP21,TBR1,NEURL4,TRAF3IP2,GALC,NCKAP1,IQGAP2,TUBGCP4,MMADHC,COPS8,ZNF638,POLL,FERMT2,PRRC2B,EML4,GSN,KIF3A,CLASRP,RASSF8,ARHGAP19,ELOVL5,HMGB1,HSPA1L,SOWAHA,DOCK7,ITGAV,KIF5C,KLC1,KTN1,PACRG,SMAD9,MBNL1,SRSF12,MKLN1,AFDN,MOV10,GIT1,BLOC1S2,PTOV1,MYO7A,NDUFA5,NEFM,NEK1,NF1,TBC1D25,OCRL,OPA1,PCDH9,CDK18,PFKFB2,OLA1,PFKP,PIK3R1,PLEC,MAPKAP1,MBOAT7,MED1,PPP2R5C,PPP2R5E,RAB39A,PSMD13,UHRF1BP1,PTPN13,OCIAD1,EML5,PTPRG,RIPOR1,TMEM231,RAB3IL1,CEP97,CCDC40,ATG16L1,RADX,ZYG11B,RFX3,KIF7,RPRD1A,RNH1,SETD5,TCP11L1,RTKN,CLIP1,COPZ1,FUZ,SHMT2,AMBRA1,URGCP,PPP4R3A,EPN2,DHX30,CCDC88A,GKAP1,IFT122,WDTC1,SPATA7,CLUAP1,CAND2,UHRF1BP1L,MYCBP2,ERC1,ARHGAP26,KIF1B,IQSEC2,CLASP2,MPRIP,NEK4,KLHL7,SUPT5H,DNAJC9,ANKRD28,MLST8,EXOC7,CAMSAP2,EHBP1,KIAA0930,RPGRIP1L,CLASP1,OBSL1,CRTC1,TF,DICER1,TIAM1,DDHD1,PARD3,TP53BP1,TP53BP2,CDK20,TSC2,SSBP2,HSPBP1,TUBB1,EIF4ENIF1,UBE2H,AMOT,WRN,XRCC4,TMEM237,DPYSL5,SPIRE1,WNK1,DNALI1,SNX27,GOPC,UBE3B,RSPRY1,IFT88,GAN,LAS1L" Pubmed 24194600 "The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data." Pubmed 5.02E-27 1.15E-21 2.51E-23 3.24E-22 216 1051 "DPF1,SYN3,ADAR,ELFN2,SLITRK1,ADCYAP1R1,ESYT2,LRFN2,SLC24A4,GPR158,CASKIN1,HACE1,BBOX1,PKP4,PARG,CPNE5,AQP6,ARRB1,ARRB2,ATP1A3,STX16,ATP2A2,ATP2B1,DOCK11,ADAM23,BACH1,ADGRB2,SYNJ1,JAZF1,CACNA1I,GPC2,IL33,CA4,CAST,HIP1R,RHBDL1,CCK,KRIT1,FMNL3,CERS5,USP2,SCARB1,CDH10,ARHGAP33,CHN1,CHRNB2,JAM2,PPT2,NRXN1,ABCG2,TMEM184B,CNR1,COL4A5,COL9A2,COX4I1,CP,HAPLN1,CRYM,ARHGEF10,SIPA1L1,CST3,GREB1,NRSN1,PPP6R2,GPSM1,BOC,SNPH,PHF19,RIMS3,SPOCK2,AIF1L,DBN1,DCT,KIAA0753,KLHL3,RPS6KL1,LPAR6,NCALD,ADGRV1,CLVS1,ABCA8,PRAM1,SLC9B2,FGFR1,BAIAP2,HPCAL4,RGPD5,FOXO3,EVL,SEMA4D,SGIP1,DCTN2,CINP,KHDRBS3,NSG1,HHIPL1,GAD2,SYT17,STARD10,ALDH1L1,GHR,DBF4,TOX3,GNAO1,TDRKH,GPR17,GPR19,GPR22,TPPP,PARD3B,GRM3,PTPN5,BVES,RABL2A,GYG1,RASSF8,PADI2,PACSIN2,GABARAPL2,IL6R,IL6ST,KCNC2,KCNJ3,KCNJ9,KCNJ11,LIFR,FGFBP3,NCOA7,LSS,MAG,LYPLAL1,MAT2A,ADAM11,NEFH,NRCAM,NTRK2,IGSF11,OXTR,P2RX7,PC,PCSK5,PDE1B,PENK,TMOD2,PFKFB4,KCTD15,PLCB2,PCDH18,PRIMPOL,MAPKAP1,STRN3,SPATA6,MBOAT7,EPB41L4B,PRKAB2,PKIA,FITM2,PRODH,NDUFS7,VPS13C,SH3TC2,IQSEC3,ENOX1,RDX,CARF,GSTCD,TMEM100,SNX22,NEK11,ELMOD1,SLC1A3,PEX26,DHX30,SLC8A3,SLC20A2,MAPKBP1,ZHX3,SPP1,KIF1B,TSPYL2,THSD1,SST,AJAP1,MLC1,RHBDL3,DNAJC9,POPDC3,TMEM136,WSCD1,TPCN2,USP22,TMEM151B,ATP13A2,DICER1,AP4E1,FBXL16,GALNT17,ARL10,PARD3,ZNF346,TRPC3,SSBP2,TST,FRRS1L,SLC13A3,LGI4,NDRG4,LYPD6,ZNF142,FTSJ1,ADAMTS9,SNX27,CAB39L,PARP11,FZD3,IFT88" Pubmed 10470851 Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.30E-26 2.98E-21 6.33E-23 8.18E-22 53 104 "ADCY2,MTMR2,NCOR1,ARHGEF4,KIAA1109,HBS1L,SYNPO,KCND2,MYT1,ANKHD1,IQSEC3,PCMTD2,SCAF8,PPM1E,NLGN1,EPN2,SLC8A2,SHANK2,SORCS3,IGSF9B,LIMCH1,PDZRN3,USP33,DOP1A,SON,WDTC1,MYT1L,ERC1,PEG10,CDK19,RAP1GAP2,MAPK8IP3,ZC3H4,PRRC2C,ZFR2,ATP11A,TACC1,KAZN,EXOC7,CAMSAP2,FAM208A,KIAA1107,AGTPBP1,IQCE,SATB2,WASHC4,USP22,DOCK9,PHF24,TNS2,TRO,AMOT,NSD2" Pubmed 17474147 Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Pubmed 1.57E-26 3.62E-21 7.53E-23 9.74E-22 101 330 "ABAT,ABR,NCKAP5,CSMD2,BIN1,ANK2,SEMA7A,MAP4K3,PPFIA4,CNTNAP1,PPFIA3,SHROOM2,PRX,RGS20,CHRD,HCN2,SYNJ2,CAST,NFS1,CCKBR,LRBA,CDC27,DLGAP2,DLGAP1,DLGAP3,CNTFR,AKAP6,MYRIP,CSF2RA,RIMS2,G3BP2,DLG4,DNM1,DNM2,CELSR3,EFS,EXTL1,SEC24B,POLR1B,FOXF2,FLNC,AFF2,NBEA,PNMA2,FYB1,FYN,GABBR1,GABRA3,GAD1,BRPF3,ZNF274,CSDC2,GHR,GRB10,RAPGEF1,GRIN2D,MAP4K5,NXPH3,GPR45,JAK2,KCNN1,MAP4,MIA2,P2RX7,PIK3CD,PIK3R1,PKD1,SH3KBP1,PPP3CA,PTPRN2,DUSP15,RGS7,RIT2,RYR1,SHANK2,ZKSCAN3,SMARCC2,SMARCD3,RIMS1,KIF13A,TNIK,NFASC,EPB41L3,ZC4H2,VPS13A,TAL1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMPO,TP53BP2,PDIA2,WIPF1,ZNF32,CSDE1,SCG2,WNK2,RTN4" Pubmed 25979088 Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Pubmed 2.68E-26 6.16E-21 1.26E-22 1.62E-21 34 44 "CACNA1A,CACNA1D,CAMK2B,CAMK2D,CLCN3,SLC32A1,CACNG2,TUBB3,GABRA3,GABRB1,GABRG2,GAD1,GAD2,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNB1,KCNC2,KCNH2,KCNK1,KCNQ3,RELN,SCN8A,SLC6A1,STX1A,KCNAB1" Pubmed 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 3.34E-26 7.68E-21 1.54E-22 1.99E-21 185 852 "ACLY,ADAR,KIAA1211,ESYT2,OGT,EP400,USP28,PARG,ZBTB10,CCAR2,ATP2B1,ATP2B3,BLM,WASF1,BTRC,FOXK1,SPAG9,RUNX1T1,PRC1,LDB2,CBFA2T2,SYNGR3,ARHGEF2,CDC27,ZMYM4,LRWD1,COPB2,FOXN3,CHI3L2,ARMC8,SLC4A7,SMARCAL1,CHD1L,CPS1,CREM,SH2B1,NCOR1,NCOR2,CTH,CTNND1,PUM1,GAPVD1,KIAA0513,LIN54,MAML1,YTHDC1,DCTN1,ZEB2,MYEF2,ZC3H11A,DLX1,ABI1,DUSP9,DYRK1A,FARSB,E2F6,EEF1D,PHF20L1,SUGP2,ABI2,EIF4G1,GPHN,ACSL4,CAMSAP1,FHL1,FOXG1,FOXF2,FOXM1,FOXO3,FLNC,FLYWCH1,NELFCD,SMC2,STAG2,GAA,NCKAP1,IQGAP2,BRD8,GK,TCERG1,GLYR1,ATF7,NR3C1,PSIP1,ACOT7,HSPA1L,HSP90AA1,C5orf24,RBPJ,KIT,KPNA5,KTN1,LIG4,SMAD9,MBD1,MDM4,MEF2C,MEIS1,MOV10,MXI1,MYCN,MYH7,NEFM,NFIA,NFIX,NFYA,NOVA1,NOVA2,PBX1,A2ML1,PKM,ING3,KANSL1,MAPK9,BCAS3,QRICH1,ANKHD1,UHRF1BP1,USP47,ZCWPW1,ARID4A,REV3L,RFX2,RFX3,TTLL7,KIF7,MRPS18A,RNASEL,ZFHX4,RXRA,TRAPPC13,FAM192A,SALL1,SATB1,KIF27,PUF60,FRMPD1,FBXO11,WDR47,KANSL3,EPC1,SMARCA4,SMARCC2,SMARCE1,FNBP1,RBM26,NPAS3,SRPK2,POGZ,GSE1,PRRC2C,DNAJC9,ANKRD28,MMS19,TAF9,AGTPBP1,FBXW11,TBL1X,TCF4,SIN3B,SATB2,TCF12,OBSL1,NACC2,CABIN1,TP53BP1,TPM1,CDK20,TPM2,NR2C2,TRO,TRPS1,ZMYND8,HIRA,MEAF6,ZIC2,SMARCAD1,INTS3,EMSY,PRDM10,TUBA1A,FIP1L1,GOPC,JMJD1C,FXR1" Pubmed 19554387 The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Pubmed 3.84E-26 8.83E-21 1.73E-22 2.24E-21 49 91 "ABAT,ASIC2,ACHE,SLC12A5,OGT,SEMA4G,CALB2,CABP7,KCNAB3,HOMER3,CNR1,WHRN,SLC32A1,SPOCK3,ELAVL2,RCAN2,NSG2,NSG1,GAD1,GAD2,GRM1,GRM2,GRM3,GRM5,GRM8,RASSF8,SHISA6,LRRTM1,KCNA2,KCNMA1,KIT,NEFH,HCN1,PENK,SERPINI1,EML5,IQSEC3,ZMAT4,BCAN,SLC6A1,SNCA,SST,CDH22,TNR,TRPC3,VGF,VLDLR,TRIM9,LYPD6" Pubmed 19030180 Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. Pubmed 4.02E-25 9.25E-20 1.78E-21 2.30E-20 57 126 "ASCL1,NRP2,CDH8,LHX2,ZNF521,SLC32A1,CRYM,TIAM2,DLX1,OLIG1,DRD1,EBF1,EGR3,EMX2,OLIG2,ERBB4,ETV1,FOXG1,TBR1,GAD1,NKX6-2,SALL3,GBX2,GNAL,GUCY1A1,HES5,LMO1,MAP2,MEF2C,MEIS2,NKX2-2,NTRK2,PAX6,PBX1,PENK,POU3F2,POU3F4,POU6F1,PROX1,FEZF2,ROBO1,ROBO2,RORB,RXRG,ARX,SLIT1,SOX1,SOX10,SOX11,TAC1,TCF4,CUX2,HEY1,NR2E1,ZIC1,SLC17A7,SLC17A6" Pubmed 23055939 A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. Pubmed 6.84E-25 1.57E-19 2.96E-21 3.83E-20 45 81 "ADD1,SLC12A5,WDR35,MADD,CASK,CADPS,DYNLL1,SYNJ1,CACNA1B,CACNA1D,CACNB2,PTBP2,CHGB,ERC2,RIMS2,SNAP91,DTNA,SH3GLB1,ATP13A4,SGIP1,SORBS1,ERGIC3,RAPGEF6,SRRM4,CIT,FAM222A,KCNQ2,SCG3,MYO7A,NRCAM,PPP3CB,VPS13C,STUM,NUBPL,RUFY2,KANSL3,SNAP25,SCN3B,DOP1A,EMC1,KIF1B,CLASP2,MCF2L,PARP6,SNX14" Pubmed 17043677 Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Pubmed 2.15E-24 4.93E-19 9.14E-21 1.18E-19 62 151 "SPARCL1,GPRASP2,ANK2,PPFIA2,DST,KALRN,CLU,AKAP6,NCOR2,PDE4DIP,KIAA0408,MATR3,DCTN1,TIAM2,CEP170,SNAP91,SRGAP3,DMD,DPYSL2,ABI2,WAC,OLFM1,DCTN2,NBEA,SMC2,CAMKK2,DISC1,KIF3A,KIF5A,IPO5,SFR1,NEFM,PDE4B,CCSER2,KANSL1,PPP5C,ROGDI,PPM1E,CNKSR2,SYBU,ZNF365,CDK5RAP3,CCDC88A,SMARCE1,MYT1L,TNIK,SPTAN1,TAB2,GSE1,EXOC7,WWC1,AGTPBP1,TRIM2,SYNE1,FRYL,TRIO,TUBB2A,CCDC136,CCDC14,ZNF17,TRIM9,TFIP11" Pubmed 16987237 Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. Pubmed 2.89E-24 6.63E-19 1.21E-20 1.56E-19 40 66 "ACHE,CACNA1A,CACNA1D,CCK,DLGAP1,NRXN1,NRXN2,PICK1,DLG4,DRD1,DSCAM,ENO2,GPHN,GABRA1,GABRA2,GABRA4,GABRA5,GABRB1,GAD1,GAD2,GALR1,PCLO,GRIA1,GRIK2,GRIN1,NOS1,NPY,CNTN3,PCSK1,PCSK2,PDYN,PENK,SCG5,RIMS1,SST,SSTR1,STXBP1,TAC1,TACR1,CNTN2" Pubmed 17145500 PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Pubmed 3.66E-24 8.40E-19 1.50E-20 1.94E-19 53 114 "SLITRK1,FZD9,LRFN2,SEMA6A,LRFN1,SEMA7A,LRRC4C,SEMA4G,CADM3,ADAM23,NRP2,CALB2,NECTIN3,LRRC3B,PLXNA4,SLITRK5,SEMA3D,EFNA2,EFNA3,PLXNC1,EPHA5,SEMA6C,SEMA4D,NTNG2,L1CAM,MAG,MBP,ADAM11,ADAM22,MDGA1,NCAM1,SEMA5B,PLXNB1,PLXNB3,SDK2,PRKCB,PRKCG,SEMA6D,LRFN5,NTNG1,SLITRK3,LRRC4,TAC1,SEMA4A,DCBLD1,TMPRSS5,CADM1,CADM2,SEMA3B,SLC17A7,FZD3,NETO2,NETO1" Pubmed 27880917 Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Pubmed 4.59E-24 1.05E-18 1.84E-20 2.38E-19 208 1048 "RALGAPA1,ARID1A,GPRIN1,ADD2,USP31,ESYT2,MTUS1,AK2,CDC42BPA,ANK3,PPFIA1,PKP4,CACHD1,PPFIA3,APP,CDC14B,PPP4R4,MADD,CASK,ARHGAP5,NUMB,CCAR2,STX16,ATP2A2,ATP2B1,MTMR9,BLM,MTMR3,MTMR2,WASF1,BTRC,CANX,SPAG9,CCNH,MTMR7,AIFM1,ARHGEF2,CDC25B,NUMBL,COPB2,CBARP,ZFYVE9,CLTA,CLTB,CLTC,AKAP5,COX4I1,ACBD5,FAM171B,CDC42BPB,NCOR1,NCOR2,CTNND1,PUM1,PPP6R2,NOS1AP,ARHGAP32,ZFYVE16,TBC1D5,DAPK3,DBT,KIAA0753,SMG7,WDR20,SEC16A,DMD,ACOT8,RCAN1,DTNA,DTNB,DUSP9,CNNM1,EGFR,ABI2,KCTD3,SORBS3,PLEKHA1,EPB41L1,EYA1,ACSL4,TUBA1B,FDFT1,FECH,SEC24B,BAIAP2,ATP5PD,CAP2,NBEA,CSPG5,PNMA2,ZNF512,NEURL4,GAB1,GLYR1,TNRC6A,ZNF638,PRRC2B,GPD2,PTPRT,PTPN5,HMGB1,HSP90AA1,SCIN,C2CD4C,KCNMA1,PPM1L,MYO5A,ODF2,OPA1,PALM,PC,DUSP26,SSH1,PIK3R1,FTO,PSAT1,PMS2,PPM1B,PTPA,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PPP5C,MAPK3,MAPK8,MAPK9,PSMD13,MTMR10,PTPN13,PTPRB,OCIAD1,PTPRD,PTPRE,PTPRG,PTPRH,PTPRN,PTPRN2,PTPRZ1,SLC6A15,ZYG11B,KIF7,ROBO1,KIRREL1,ELP2,FBXW7,MCMBP,SBF1,ATXN2,PPP1R9A,PPM1E,SHMT2,PAAF1,PPP4R3A,CCDC88A,SLC12A2,SLC12A4,CDK5RAP2,EMC1,MYCBP2,ERC1,SPTAN1,TAB2,CLASP2,ITPRID2,ERBIN,GANAB,GSE1,SUPT5H,SYNE2,VPS13A,ANKRD28,AGTPBP1,FBXW11,RPGRIP1L,PSD3,TNS2,GPRIN3,FBXL16,TIAM1,MTMR14,TJP1,TMPO,TNS1,TP53BP2,TPD52,TPD52L2,ELP5,TRIO,STXBP4,TRPS1,TSC1,TUBB2A,CADM1,UBTF,USP1,CCDC14,NSD2,RICTOR,XPO1,FMN2,SLC38A1,SNX27,GOPC,ST7,NHSL1,AAAS" Pubmed 20201926 Human variation in alcohol response is influenced by variation in neuronal signaling genes. Pubmed 4.64E-24 1.07E-18 1.84E-20 2.38E-19 66 171 "ASIC2,ACTN2,DSCAML1,ADRB2,DDO,ASPA,BMPR1B,CACNB2,CCKBR,LARGE1,CHRM1,CHRNA4,NRXN1,ENTPD4,FEZ2,VCAN,ERC2,DLG4,DYNC1I1,DOCK2,SORBS1,GAD1,GAD2,GALR1,CPLX1,GLI2,GLRB,ZNF638,GNAS,PCLO,GRIK1,GRIK4,ADAMTS13,ADAMTS8,GRM7,GRM8,PTPRT,HLF,SYNPO,IRF8,KCNH1,MATN3,MYO6,MYO7A,NEFM,PDE4B,PDE4D,PKD1,PTPRB,PTPRD,PTPRE,PTPRG,PTPRN2,PTPRZ1,QDPR,ROBO2,RORB,RYR3,NLGN1,CDK5RAP2,MYO16,ERC1,DICER1,PDSS1,TSC2,PCDH15" Pubmed 15345747 Phosphoproteomic analysis of the developing mouse brain. Pubmed 8.19E-24 1.88E-18 3.19E-20 4.12E-19 79 236 "ABCF1,ADD1,ADD2,AMPH,APBA2,CCAR2,PTBP2,CAMK2D,CDK11B,DCLK1,DLGAP1,MAP4K4,PCYT1B,AKAP12,CRMP1,FEZ1,APPL1,CTNND2,PPP6R2,GPSM1,DBN1,SNAP91,PARD6A,G3BP2,TMCC2,EPB41L1,DCTN2,OGA,GAP43,HTATSF1,GRB10,KIF3A,ITIH2,KIF2A,ARHGAP12,MAP2,MAP4,MAPT,SAMD14,NACA,HNRNPM,NAP1L1,NCAM1,SFR1,NEK1,PALM,PDE1B,CAMKV,KCTD15,CEP41,MAPK8,USP47,FAT4,NUDT11,CCDC25,RPS6KA2,CLIP1,AMER2,ITSN1,CNKSR2,SYBU,EPN2,SMARCC2,TMCC1,TNIK,KIF21B,SOX11,CLASP2,EPB41L3,SYN1,COBL,CAMSAP2,ARHGEF12,TPD52L2,EIF4ENIF1,TBC1D15,REEP1,TUBA1A,RTN4" Pubmed 19322201 Ubiquitin-mediated proteolysis of HuR by heat shock. Pubmed 9.65E-24 2.22E-18 3.70E-20 4.77E-19 291 1671 "SDE2,ARID1A,NDRG3,ADAR,RNF150,ADRA1D,MTA3,BIN1,USP28,ANXA7,APAF1,FAM131A,API5,MIER1,PDXK,TMEM263,CASK,ATM,ATP2A2,RNF182,MTMR9,ADAM23,BARD1,BCL2L2,FUBP1,MTMR2,OSGIN2,CALM1,PTBP2,CANX,CAST,SLC16A4,NEURL1,ARHGEF2,SEPT7,CDC42,FOXN3,CNOT8,KMT2C,QKI,COL4A5,SUMF2,BTF3L4,TBPL1,BAG4,ZNF521,CPS1,PREPL,C2CD2,ABCG1,CSNK1E,OSBPL3,CSNK1G3,PDE4DIP,APPL1,CTH,PUM1,MYADM,FGFR1OP2,GAPVD1,HDAC4,CENPL,TM9SF4,LIN54,TOMM20,CTIF,AIF1L,SPATA2,ELMSAN1,ZEB2,KLHL3,BLOC1S6,DDX46,GUCD1,SMG7,G3BP2,FAM107B,DLG3,DLG4,USP3,DPYSL2,PDCD6IP,GNE,DYRK1A,GOLT1B,ANKRD46,SYT15,APH1A,MBNL2,ASB3,PLEKHA1,STARD3NL,PAN3,EPB41L1,SLC43A2,STX2,SRRM1,KATNAL1,F3,ACSL4,TUBB3,FECH,PRKAG2,FOXO3,SEMA4D,FLYWCH1,ZBED3,UFM1,FAM49B,ATP2C1,CELF1,STAU2,OGA,AHCYL1,BRPF3,ZMYND11,ZNF234,MTHFD2,GART,C1QL1,RNPS1,SPIN1,GLYR1,ZNF638,GPM6B,EML4,GRB10,NR3C1,CIT,RABL2A,MAP4K5,MUM1,ZHX1,ARHGAP19,ELOVL5,GABARAPL2,HP,FAAP20,RBPJ,TJAP1,ITPKB,SLC35G1,KCNK1,LAMP2,HECTD2,MAT2A,LDLRAD3,MID1,MITF,MKLN1,GIT1,SESN3,MTR,NAP1L1,NFIA,NHLH1,CNOT4,NPTX1,SMIM11A,DDR2,OCRL,ODF2,OLR1,OPA1,PBX1,PCDH9,PFKFB3,SERPINE2,SSH1,SNX10,SLC25A23,SMIM7,ZNF426,PMP22,STRN3,RC3H2,ING3,EPB41L4B,TNPO2,SH3KBP1,DRAM2,IRX1,MED1,PPP2R5E,PPP3CB,PKN2,PTK2,RAB5B,ATG16L1,ZDHHC14,RDX,ZYG11B,DUSP15,RPRD1A,ZNF532,C12orf49,CCDC25,SPIN3,ACER3,FAM192A,AP1AR,SAFB,SCP2,CASC3,SFPQ,SGK1,KIF21A,FBXO11,FNDC3A,R3HDM2,CCDC92,PEX26,BTBD3,SEPHS1,SLC9A5,NAPB,SMARCC2,RCOR3,LIMCH1,USP33,TRERF1,FNBP1,CLUAP1,KIF1B,IQSEC2,ZBTB43,SSTR2,EPB41L3,LARP4,SS18,NXT2,STAU1,GSE1,PRRC2C,KAZN,CAMSAP2,FAM208A,TBL1X,MGRN1,SATB2,TCF7L2,TRIM2,TCF12,CLASP1,PUM2,SIK3,SIRT1,DICER1-AS1,C18orf54,AP4E1,ZMAT3,TGFBR3,SLC44A1,HEY1,TJP1,ZFP91,LRRC8A,RBFOX2,TPM1,TPM3,NEIL2,TRPC1,HIRA,UBC,RPRM,UBE2H,PITPNB,OSBP2,VAV2,MEAF6,CCDC14,WIPF1,RICTOR,XPO1,ZBTB14,ZIC2,REEP1,DHX33,INTS3,MAP3K12,CSDE1,EVI5,SNX27,KCNAB1,PDSS2,KAT6A,PHTF2,FAM219B,RSPRY1,FXR1,NETO2" Pubmed 28558017 A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. Pubmed 2.28E-23 5.25E-18 8.60E-20 1.11E-18 43 79 "PCDH19,SEMA6A,ALCAM,PCDH10,SEMA7A,CDH2,CDH8,CDH10,TENM4,LYPD1,EFNA2,EFNB3,PLXNC1,TENM1,EPHB1,NRN1,DNER,GFRA1,GFRA2,KIRREL3,NTNG2,PCDH11X,WIF1,KIT,MDGA1,NTRK2,SDK2,FAT3,LRRN3,RET,LGI2,EPHA10,NTNG1,CLSTN1,IGSF9B,CLSTN2,ASTN2,CADM1,VGF,LRP8,NETO2,NETO1,CBLN2" Pubmed 20059953 A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Pubmed 4.60E-23 1.06E-17 1.70E-19 2.20E-18 253 1398 "DPF1,KIDINS220,MTA3,NR0B1,PLA2G6,MRTFA,ZNF687,ANK1,LCORL,PHF12,ARNTL,ASCL1,BACH1,BARD1,FUBP1,JAZF1,FOXK1,RUNX1T1,LDB2,CERS5,CCNH,CCNT1,CHGB,CNOT8,LHX2,VAX2,FHL5,MAGED1,TBPL1,ZNF521,ZFP28,ZNF385A,FAM171B,RBM39,CREB5,RNF14,HINFP,NCOR2,SNCAIP,PPP1R16B,PHF14,ST18,PYGO1,TOX,PHF19,MAML1,ZEB2,ZBTB24,MYEF2,B3GAT3,MED24,OLIG1,NR1D2,DMTF1,E2F5,E2F6,EBF1,ANKRD46,FEM1B,HEYL,EGR3,ASB3,ELAVL2,ING4,EMX2,EN2,OLIG2,ERCC2,ETV1,EZH1,KAT8,PPP1R1B,POLR1B,FHL1,FOXG1,FOXF2,FOXM1,FOXO3,NELFCD,ZNF512,ZMAT1,ZMYND11,SALL3,ZNF274,GBX2,CSDC2,PPARGC1A,BRD8,ZNF276,TCERG1,GLI2,TOX3,MSL3,HTATSF1,INSM2,PRRC2B,ATF7,STON1,TMEM121B,NR3C1,PRDM5,KAT7,PSIP1,ATOH8,MAEL,KLF12,MIER3,HLF,HNF4G,ZDHHC15,HSF2,HTR5A,IRF8,IFI16,ZNF546,RBPJ,HES5,LMO1,LMO2,SMAD1,MEF2C,MEIS2,MID1,MITF,MXI1,MYCN,NACA,RCOR2,NEUROD1,NEUROD2,NFIA,NFE2L2,NFIX,NFYA,NKX2-2,CNOT4,CHAMP1,PAX6,PBX1,ENPP2,DUSP26,ZNF655,ZNF426,CDIP1,PRRX1,ING3,POLR2F,POU3F4,POU6F1,IRX1,PPARA,MED1,PPP3CB,MAPK8,PROX1,TMEM260,ZIK1,ZSCAN2,FEZF2,DPF2,RFX2,RFX3,RFX4,UBR7,PBRM1,CARF,RORB,ARMH4,FBXW7,SOX8,KCNIP3,ZNF354C,RXRA,SATB1,HES6,ZFP2,SOX6,ZFP30,ARX,ANKRD6,PKNOX2,SIRT2,SCMH1,ATF7IP,ZKSCAN3,ZFP1,ZNF667,ABTB1,SMARCA4,SMARCE1,KDM4B,TRERF1,SOX2,SOX10,SOX15,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,KANK1,SUPT5H,MMS19,TAF6,TAF9,TAL1,TBX15,TCEA1,TCF4,SIN3B,ZFP90,TCF7L2,TCF12,CRTC1,SIRT1,ZFPM2,THRA,GZF1,HEY1,NR2E1,HEY2,TMPO,TP53BP1,RBFOX2,TRPC3,TRPS1,ZMYND8,SSBP2,ZKSCAN5,UBTF,VAV1,CLIP2,ZFP37,ZBTB14,ZIC1,ZIC2,ZIC3,ZNF23,ZNF24,ZNF32,ZFP41,ZBTB38,ZBTB16,POLR3H,ZNF189,MEIS3,MAP3K12,CSDE1,CERS6,JMJD1C,ZNF248,DPF3" Pubmed 18519826 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Pubmed 1.53E-22 3.52E-17 5.59E-19 7.22E-18 48 101 "ADCY2,DSCAML1,SORCS1,MTUS1,ADGRF5,ASTN1,TMEM108,CACNB2,LARGE1,MAGI1,CHN2,NRXN3,CREB5,ERC2,DAPK1,DPP6,DSCAM,ATP8A1,FGF12,TACC2,ST6GALNAC3,NRG3,LUZP2,GRIK1,GRIK2,PTPRT,OLFM3,KCNK2,KCNN3,NELL1,NECAB2,PPP2R2B,LAMA1,PTPRD,NEK11,SLC1A2,SNAP25,TNIK,SOX5,ZNF423,NPAS3,CLSTN2,KAZN,TEK,CSMD1,TRIO,BCL2L13,PCDH15" Pubmed 10718198 Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. Pubmed 2.00E-22 4.60E-17 7.19E-19 9.29E-18 60 153 "HECW2,KLHL13,CASKIN1,PCDH19,KCTD16,RTL9,HACE1,TBC1D14,KIAA1324,SORCS2,WDR35,DISP3,TXNDC16,CC2D2A,TAOK1,LRRC7,SEMA6A,USP35,CEP126,ARHGAP20,CARNS1,MARCH4,PCDH10,UNC79,FAM135A,KCNT1,SYT13,MRTFA,ZNF687,COG1,ZFP28,SH2B1,TENM4,CHD5,APPL1,INTS1,MYEF2,CASP8AP2,PDCD6IP,GPHN,SPEG,KIAA1109,SORBS1,ATP2C1,PCDH11X,NFIA,SSH1,PACSIN1,VPS13C,RALGDS,SCN3A,KANSL3,RCOR3,SYT4,LRRC8A,STOX2,ADAMTS9,NAV2,JMJD1C,NHSL1" Pubmed 12975309 "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Pubmed 2.20E-22 5.05E-17 7.76E-19 1.00E-17 195 987 "SLC25A25,SLITRK1,GRAMD1B,ADORA3,NLGN4X,KIAA1324,C1QTNF1,C1QTNF3,BCAR3,C6orf89,PI16,FAM131A,LRRC4C,PTCH2,CHRD,TMEM108,CADM3,FGF17,ST3GAL5,SGCE,SLC25A14,LGI1,CRLF1,ADGRG1,JAM2,TAOK2,NDST3,PPT2,TPP1,FAM19A5,SLC25A27,SUMF2,MFSD4A,PNKD,LRRC3B,PLXNA4,ECE2,BOC,MYADM,INTS1,SPOCK2,AIF1L,HEPH,TMEM130,LYPD1,SPOCK3,NTM,TMCC2,HS3ST2,CD99L2,TOM1,GOLT1B,SEZ6L2,SEMA3D,EEF1D,SIDT2,APH1A,PCOLCE2,STARD3NL,PAN3,HSD17B14,LRRC17,ENPP6,TLR7,CD320,FAM198B,PCYOX1,ATP13A4,TMEM107,HVCN1,ST6GALNAC3,SARAF,HHIPL1,PHYHIPL,MEGF11,DKK3,GALNT15,ERAP1,DNER,KIRREL3,LYVE1,DHRS4,NTNG2,LUZP2,LNX1,ADGRA3,CNDP1,ADAMTS13,CACFD1,CLASRP,COQ10A,TMEM25,MFSD2A,FICD,LINGO1,RNFT2,WIF1,NXPH3,MAN1B1,VSIG4,SCRG1,ZDHHC15,NEGR1,LRRC25,LRRTM3,LRRTM1,ITGA7,OLFM3,KCNQ2,CLEC18A,MATN2,PTOV1,SCG3,RSPO2,LAYN,FXYD6,DNHD1,CLEC9A,IGSF11,CYTL1,SEMA5B,SMOX,TRHDE,DRAM2,LRRN3,GRAMD1C,GDPD2,MDGA2,PIGG,TMEM231,ATG16L1,SUSD4,BSDC1,ZDHHC4,KIF7,GLDN,STK32B,ST6GALNAC6,WLS,DGLUCY,DRAXIN,SCN2B,LRRTM4,TNFRSF19,IL17RB,NTNG1,SHC4,BCAN,LGI3,IGSF9B,ANKRD36,GLT8D1,IZUMO4,UNC5B,THSD1,LRRC4,SULF2,TAC3,SEMA4A,UNC5D,ALG1,VWC2,PCDHB10,HHIP,ENHO,TMEM9,RELL2,LRRC8A,FAM124A,CSMD1,SEZ6L,CHST5,CA14,TMEFF2,CADM1,FLRT2,FLRT1,MTCH1,TOM1L2,TSPAN11,CLDND1,LGI4,LYPD6,CA10,GDPD5,LMAN2L,TMEM178A,SIGLEC10,PLD4,RSPRY1,MSRB3,PIANP,NETO2,CBLN2,ST8SIA2" Pubmed 21145461 Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Pubmed 3.97E-22 9.11E-17 1.38E-18 1.78E-17 289 1696 "CPNE2,ABCF1,ACADM,ACLY,RBM10,ARID1A,ADAR,TMCC3,GALNT13,BRAP,AP1B1,KLHL13,AK2,SMIM17,SRPX,GPRASP2,LRCH2,CCDC146,PPFIA1,ANXA7,APBB1,TNRC6C,API5,PDXK,ARHGDIA,CAPRIN2,ASPH,ZBTB10,CCAR2,DYNLL1,ATP1A1,ATP1A2,ATP2A2,MTMR9,BCL7A,DCAF5,BLM,LDHD,FUBP1,NAE1,MTMR3,BTRC,CALM1,CAMK2G,CANX,CBR1,AIFM1,ARHGEF1,SCARB1,ZMYM4,CCPG1,SRSF11,SOCS6,DLGAP3,MYL6B,CLTA,CLTC,FBXO7,ARMC8,MAGED1,TCEAL2,BAG4,RBM39,TENM4,SEC24C,SOCS5,CTNND1,PUM1,GPSM1,DCAF4,EDRF1,DCAF8,MATR3,DCTN1,HP1BP3,FBXL5,COPS7A,DDX46,RHOBTB1,G3BP2,SEC16A,DLG4,NYAP1,DYNC1I1,PDCD6IP,DNAJB6,DNM1L,EEF1A2,FEM1B,EEF1D,KLHL5,YAF2,ASB3,KCTD3,EIF4G1,EIF4G2,COPS4,ELAVL2,SRPK3,EML1,ENO2,SRRM1,MRPL37,TUBB3,TUBB4A,RACK1,PRMT5,FECH,SEC24B,POLR1B,AMOTL2,SEC23B,SYNCRIP,FLNC,ANKFY1,NOP56,DCTN2,STAU2,GABRB1,HBS1L,FAM120B,MTHFD2,GART,COPS8,RNPS1,GLDC,GLS,TNRC6A,ZNF638,HTATSF1,POLL,RAB40B,GPT2,CCDC184,NUDT21,TUBA1C,PTPRT,MUM1,NXPH3,MAN1B1,DDX19B,ATXN2L,BACH2,HMGCR,HNRNPK,HSPA1L,HSP90AA1,KNDC1,TUBB2B,KCNH2,KLHL23,KHK,KIF5C,KPNA5,IPO5,ASPRV1,MAP4,MAT2A,LRP1B,KCTD6,MOV10,MPP2,DBNL,CCDC80,PTOV1,MYH3,NACA,HNRNPM,NAP1L1,NAP1L2,NDUFA5,KSR2,NUCB2,OPA1,PCMT1,FAM98B,PFKP,CAMKV,PIK3R1,PKM,NLE1,PLEC,SLC25A23,EXOSC10,PRKAR1B,PRPH,PRPSAP2,DCHS2,MASP1,RELN,PSMA6,ANKHD1,QDPR,FAM184A,RBBP6,ZYG11B,DPF2,FIGN,RGS12,KCTD17,TTLL7,KLHL11,DCUN1D2,ARMC5,PCMTD2,RPL15,FBXW7,MCMBP,RPL38,RPS20,HSD11B1L,RXRG,RYR3,NCBP3,SAFB,ATXN2,CASC3,SFPQ,TRA2B,PUF60,MYO18A,SHMT2,AMBRA1,FBXO11,SEC31A,SLA,SLC1A3,DHX30,KDM4D,SEPHS1,KBTBD4,BTBD7,COA1,ABTB1,SMARCA4,SMARCC2,SMARCE1,UNC80,WDTC1,ZSWIM8,EMC1,MYCBP2,ERC1,SPTAN1,SRPK2,TROVE2,ZNF302,LARP4,SS18,FCHO1,STAU1,TTBK2,KLHL7,SUPT5H,ADAMTS17,DNAJC9,MMS19,ANKRD12,FBXW11,KLHL4,EHBP1,DOCK9,PCDHA6,DICER1,KCTD2,RBFOX2,TPM3,ZNF346,TUBB2A,TUBB1,UBC,RPL7L1,AMOT,TBC1D15,SF1,TRIM9,FTSJ1,PMEPA1,CSDE1,PRDM10,TUBA1A,SCG2,FIP1L1,HNRNPA3,NUP214,FXR1,SOCS4,GAN,LAS1L" Pubmed 17953485 Regulatory pathway analysis by high-throughput in situ hybridization. Pubmed 4.04E-22 9.27E-17 1.38E-18 1.79E-17 45 91 "TTYH1,ADCY8,ARHGAP5,CALB1,CALB2,SYT6,CCK,CDH8,CHRNA4,LHX2,PDE4DIP,OPTN,EFNB3,PLXNC1,FGF14,GABRB1,GAD2,PCDH17,PRUNE2,GRIA1,GRIN1,GRM1,GRM3,PTPRT,IGFBPL1,NEUROD1,PAX6,PDE1C,PDE1B,POU3F4,NKAIN4,RASGRF1,RORB,ARX,BCAN,SLA,SLC6A1,ZNF423,SST,TAC1,TCF7L2,NR2E1,HEPACAM,WNT7A,TRIM9" Pubmed 10048485 Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 7.62E-22 1.75E-16 2.57E-18 3.33E-17 47 100 "RALGAPA1,AP2A2,ADGRF5,PPFIA4,SYNJ1,TAOK2,CNTNAP2,FAM169A,SLITRK5,PPP1R16B,FAM13A,ABCA8,PCYOX1,PNMA2,WASF3,USP19,GLS,MYT1,NEFH,CDK14,SLITRK3,CNKSR2,SEC31A,CLSTN1,ABLIM3,ZNF365,DHX30,WDR47,MYO16,KDM4B,ZSWIM8,MYCBP2,ZC3H13,MCF2L2,CAMTA2,MPRIP,TTBK2,ANKRD12,CAMTA1,WWC1,EHBP1,ACSL6,DMXL2,FRYL,AHCYL2,CSDE1,RTN4" Pubmed 20436479 A genomic atlas of mouse hypothalamic development. Pubmed 7.93E-22 1.82E-16 2.64E-18 3.41E-17 68 195 "TMCC3,SEMA6A,NCOA1,ZNF445,SLIT2,LHX2,CNTFR,IGDCC3,NECTIN3,CRYM,SIPA1L1,NCAN,KIAA0513,DLX1,FEM1B,EMX2,OLIG2,SEZ6,EPHA5,ERBB2,ADGRV1,FGFR1,FOXG1,TMEM151A,DKK3,GAD1,GAD2,NKX6-2,GFRA1,NTNG2,GNAO1,GPM6B,FAM107A,WIF1,IGSF1,HES5,INSM1,KCNA2,LSAMP,NEXMIF,NAP1L1,NKX2-2,NOS1,NOVA1,NTRK3,OPRL1,PAK3,PBX1,MAGEL2,EPDR1,PROX1,RASGRF1,FEZF2,ROBO1,RORB,SEMA6D,ARX,YPEL4,SOX11,ROBO3,BHLHB9,SSBP2,WNT7A,ZIC2,ZIC3,SLC17A6,FZD3,SPATA13" Pubmed 10512203 Exchangeable gene trap using the Cre/mutated lox system. Pubmed 1.30E-21 2.98E-16 4.26E-18 5.51E-17 122 506 "RBM10,ARID1A,ALAD,MAP4K3,PKP4,DGKD,TMEFF1,ATP2B1,WASF1,MAP7,CCNT1,CD81,ARHGEF2,SRSF11,TJP2,HECTD1,MAP4K4,NIPBL,CNN3,CHD1L,NCOR1,NCOR2,TENM4,OSBPL3,SIPA1L1,CTNND1,PUM1,HDAC4,IST1,YTHDC1,DNAJC6,G3BP2,RABGAP1L,WDR20,DTNB,TSPAN5,HIPK3,SIDT2,SUGP2,MBNL2,COPS4,EPB41L1,EPB41L2,EPS8,NSRP1,POLR1B,FGFR1,SYNCRIP,ZCCHC17,TACC2,SORBS1,CAMKK2,TRAF3IP2,C15orf41,SEPT9,AHDC1,TXNL4A,GLI2,RAB30,TNRC6A,STMN2,PACSIN2,KLF12,RBPJ,KIFC3,MARK3,MAT2A,NAP1L1,NODAL,ODF2,PKM,FTO,MAPKAP1,POLR2F,PPM1B,KANSL1,WBP1L,QRICH1,PTPRG,RALGDS,RNF220,KIRREL1,PCMTD2,LGR4,RMI1,CSRNP3,GALNT10,SEC31A,EPN2,TET1,MBD5,TEX2,ZNF423,SRPK2,ERBIN,KANK1,ATP11A,TACC1,KAZN,CAMTA1,TAF9,WWC1,TBCEL,SMG6,EHBP1,TCF4,TCF12,CLASP1,FRYL,DICER1,GZF1,TIAM1,ZFP91,LRRC8A,PARD3,C9orf85,CADM1,MEAF6,PMEPA1,SLC38A1,CAB39L,JMJD1C" Pubmed 26673895 A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Pubmed 7.02E-21 1.61E-15 2.27E-17 2.93E-16 198 1038 "ABCF1,ADD1,ADD3,CDC7,AP2A1,AP1B1,TBC1D14,MRTFA,BEGAIN,PITPNM2,DGKZ,TNRC6C,MADD,ARRB2,PDE8B,NUMB,CCAR2,MTMR9,RIPK1,BACH1,KSR1,AP1M1,IL33,FOXK1,CFAP410,ARHGEF1,AP4M1,SEPT7,CDC25B,CDC27,EVI5L,NUMBL,DIS3L,COPB2,EPS15L1,TJP2,MAP4K4,CRY2,SEC24C,CSNK1E,CTNND1,PUM1,PPP6R2,GPSM1,NOS1AP,GAPVD1,DCAF8,TBC1D5,MAML1,SPATA2,HP1BP3,RUSC2,CEP170,SMG7,WDR20,SEC16A,DMD,MED12,TOM1,DNAJB6,DYRK1A,KCTD3,EIF4G2,EIF5,PAN3,ERCC2,RTN3,TUBA1B,TUBB3,TUBB4A,CEP78,STRADA,SEC24B,AMOTL2,SEC23B,FOXO3,EVL,CINP,ZBED3,PDLIM5,ARFGAP2,AP4B1,HBS1L,AHCYL1,RAPGEF6,SEPT9,WASHC2A,MALT1,RNPS1,DBF4,GNAS,FERMT2,PSRC1,GRB10,CLASRP,KAT7,GYG1,AGFG1,DHX35,SMAP1,RBPJ,DOCK7,KNDC1,TJAP1,ARHGAP12,LSS,SMAD1,MITF,HNRNPM,NAP1L1,NEK1,NFIA,CNOT4,OCRL,PDE4B,PDPK1,FAM98B,XRN1,EPN1,MAPKAP1,STRN3,SCHIP1,PPM1B,PRKACB,CEP41,PRKAR1B,MAPK7,BCAS3,SNRK,OCIAD1,C1orf109,PEX5,RIPOR1,CEP97,USP47,ATG16L1,RAP1GAP,ROGDI,RIC8B,GSTCD,RTKN,SARS,CASC3,COPZ1,SH3BP2,FERMT1,SEC31A,SIRT2,CCDC88A,SHANK2,BTBD7,ARFGAP1,SMARCE1,LIMCH1,WDTC1,TNIK,ZSWIM8,IQSEC2,RBM26,RAP1GAP2,TAB2,CLASP2,POGZ,ERBIN,NCDN,NEK4,SEPT8,PHLDB1,PJA1,MLST8,CAMSAP2,WWC1,AGTPBP1,TBL1X,EHBP1,TCF12,WASHC4,CLASP1,CRTC1,AHCYL2,AP4E1,MTMR14,TJP1,R3HDM1,EIF4ENIF1,GORASP1,TOM1L2,TBC1D15,RICTOR,XPO1,UPF3A,WNK1,CSDE1,FIP1L1,ACTR3B,AAAS,RNF146,LAS1L" Pubmed 15840001 Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Pubmed 8.40E-21 1.93E-15 2.68E-17 3.46E-16 120 504 "RBM10,ARID1A,ALAD,MAP4K3,PKP4,DGKD,TMEFF1,ATP2B1,WASF1,MAP7,CCNT1,CD81,ARHGEF2,SRSF11,TJP2,HECTD1,MAP4K4,NIPBL,CNN3,CHD1L,NCOR1,NCOR2,TENM4,OSBPL3,SIPA1L1,CTNND1,PUM1,HDAC4,IST1,YTHDC1,DNAJC6,G3BP2,RABGAP1L,WDR20,DTNB,TSPAN5,HIPK3,SIDT2,SUGP2,MBNL2,COPS4,EPB41L1,EPB41L2,EPS8,NSRP1,FGFR1,SYNCRIP,ZCCHC17,TACC2,SORBS1,CAMKK2,TRAF3IP2,C15orf41,SEPT9,AHDC1,TXNL4A,GLI2,RAB30,TNRC6A,STMN2,PACSIN2,KLF12,RBPJ,KIFC3,MARK3,MAT2A,NAP1L1,NODAL,ODF2,PKM,FTO,MAPKAP1,POLR2F,PPM1B,KANSL1,WBP1L,QRICH1,PTPRG,RALGDS,RNF220,KIRREL1,PCMTD2,LGR4,CSRNP3,GALNT10,SEC31A,EPN2,TET1,MBD5,TEX2,ZNF423,SRPK2,ERBIN,KANK1,ATP11A,TACC1,KAZN,CAMTA1,TAF9,WWC1,TBCEL,SMG6,EHBP1,TCF4,TCF12,CLASP1,FRYL,DICER1,GZF1,TIAM1,ZFP91,LRRC8A,PARD3,C9orf85,CADM1,MEAF6,PMEPA1,SLC38A1,CAB39L,JMJD1C" Pubmed 19906978 Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. Pubmed 8.73E-21 2.01E-15 2.75E-17 3.55E-16 60 163 "KCNH8,ALCAM,AQP4,NRP2,NGB,SYT6,CDH8,ADGRG1,SLIT2,RGS6,LRRC3B,PLCH2,KCTD8,DCC,DPP6,SEMA3D,PLXNC1,ETV1,FABP7,TUBB3,FGF14,GFAP,GFRA1,NTNG2,GRB10,WIF1,SLC35G1,KCND2,KCNMA1,LSAMP,PACRG,SYT9,MSI1,SAMD14,NCAM1,NEUROD1,NNAT,PCBP3,OPCML,CDK14,NECAB2,IRX1,PRPSAP2,RFX4,ROBO1,ARMH4,KCNIP1,SCN8A,LRRC55,MYO16,SMOC1,TAC1,TAC3,TACR1,ROBO3,TEX15,SPX,HHIP,VAV2,SPATA13" Pubmed 19386638 Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Pubmed 9.59E-21 2.20E-15 2.98E-17 3.85E-16 51 122 "ASCL1,NRP2,CDH8,LHX2,MAGED1,ZNF521,SLC32A1,CRYM,TIAM2,DLX1,DRD1,EBF1,EGR3,EMX2,OLIG2,ERBB4,ETV1,FOXG1,FOXO3,TBR1,GAD1,NKX6-2,SALL3,GBX2,GUCY1A1,HES5,LMO1,MEF2C,MEIS2,NKX2-2,PAX6,PBX1,PENK,NXPH1,POU3F2,POU3F4,POU6F1,PROX1,FEZF2,ROBO2,RORB,RXRG,ARX,SOX1,SOX11,TCF4,CUX2,HEY1,NR2E1,TP53BP1,ZIC1" Pubmed 12465718 Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 1.07E-20 2.45E-15 3.27E-17 4.23E-16 43 89 "DSCAML1,GPR158,TBC1D14,SORCS2,ASTN1,SYNJ1,ARHGEF2,DCLK1,NRXN1,ENTPD4,NCOR1,AATK,CTNND1,TM9SF4,SNAP91,ARNT2,EZH1,NBEA,PCLO,KCND2,KIF5C,MBNL1,MYT1,CPEB3,CHD9,BTBD3,ELMO2,MYT1L,ZSWIM8,UHRF1BP1L,TAB2,CLASP2,ITPRID2,MAPK8IP3,MPRIP,SEPT8,DIP2A,SYNE2,FBXW11,PCDHGA2,FRYL,ZMYND8,ZNF142" Pubmed 21516116 Next-generation sequencing to generate interactome datasets. Pubmed 1.40E-20 3.21E-15 4.22E-17 5.45E-16 212 1147 "CPNE2,SNX32,SPOP,GPRASP2,OGT,EP400,CCDC146,PPFIA1,PKP4,UPRT,RGS20,MTMR9,ZNF599,BMP7,CDK5R1,AP1M1,BTRC,CALM1,PTBP2,TRIM41,RUNX1T1,CBS,CCNH,CBFA2T2,ZBED1,CFL2,SRSF11,CHN1,FAM189A2,QKI,HOMER3,FHL5,AKAP7,MAGED1,IFFO1,CREB5,HINFP,CRYBB1,TRIM69,PDE4DIP,DZIP3,CMTM5,EDRF1,MYADM,TCAF1,RIPOR2,DCAF8,ACY3,MATR3,RIMS3,ARMCX2,FBXL5,POM121,PARD6A,SPOCK3,RAB39B,DPYSL2,DTNB,FIS1,E2F6,PHC2,HEYL,EEF1D,OPTN,YAF2,APH1A,ABI2,SORBS3,DCTN4,NCALD,SH3YL1,EFEMP1,FGF12,BAIAP2,AMOTL2,SCARA3,HPCAL4,SEC23B,IP6K2,VTI1B,ZCCHC17,HVCN1,PNMA2,SDCBP2,ZMAT1,TRAF3IP2,GAD1,MTHFD2,ZNF559,SEPT9,RUNDC3A,ZNF276,STARD3,RAB40B,FERMT2,LNX1,PRRC2B,ATF7,CACFD1,GSTM5,C1orf94,GABARAPL2,HNRNPK,ITPKB,METTL21A,KCNK1,KIF2A,KIFC3,KPNA5,LMO1,LMO2,PIK3AP1,MAT2A,MDFI,MIA2,SCAMP5,MID1,THYN1,HNRNPM,FXYD6,NAP1L3,NCF2,NFYA,PDE4D,PLP1,ZNF426,CDIP1,NECAB2,TNPO2,FA2H,SH3KBP1,C19orf57,PPP3CA,KANSL1,PRKAB2,MAPK7,MAPK9,CYBC1,PSMA6,PTPRN,FAM120C,C1orf109,PPP2R3C,RAD51D,RAP1GDS1,BEND5,RADX,KHDRBS2,RFX2,RFX3,RGS3,TMEM100,RXRG,S100B,SCP2,PUF60,SHMT2,FAM214B,SEPHS1,NAPB,NAXD,ABTB1,SMARCE1,RCOR3,FAM126B,SOX5,ZHX3,SP2,PEG10,ARHGAP26,SRPK2,ZC4H2,NXT2,FAM168A,SYT11,MMS19,TACC1,TAF9,NEU4,TRIM2,TCF12,SLC19A3,SIK3,CYB561A3,THRA,CBX5,FAM124A,TNNT1,TPM1,TPM3,WBP2,RUSC1,SSBP2,RPRM,EIF4ENIF1,MGAT5B,TBC1D15,WIPF1,ZNF23,ZNF24,MKRN3,TFIP11,PRTFDC1,SLC38A1,CSDE1,SCG2,CIAPIN1,PLSCR4,GOPC,RTN4,MSRB3,FRMD6" Pubmed 26514267 Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. Pubmed 1.98E-20 4.56E-15 5.92E-17 7.65E-16 89 320 "ACTN1,AP1B1,DISP3,USP28,RGS20,ASCL1,ATP1A3,SLC4A4,MPDZ,DST,CACNA1B,CANX,CFL2,KMT2C,COG1,HECTD1,COL9A2,SLC4A7,RBM39,CRMP1,CRYM,CTNND1,ECE2,RIPOR2,INTS1,ZC3H11A,DMD,DNM1,DPYSL2,ARRDC4,MAMLD1,EBF1,KLHL5,COPS4,ENO2,TUBA1B,TUBB3,TUBB4A,RACK1,AMOTL2,GFAP,GGT7,GNAS,GPM6B,TUBA1C,CIT,CYP27C1,MAP2,MYH7,MYO9A,NAP1L1,NASP,PPP3CA,PRKCG,PRKCZ,MAPK10,PTPN13,PTPRD,PTX3,PPP2R3C,RGS12,FAM192A,TRIM46,ASAP3,SLC12A4,SLIT1,SNAP25,SOX11,STXBP1,SYNE2,SYN1,SYN2,MMS19,ANKRD12,DDHD2,DMXL2,WASHC4,CLASP1,PCDHB10,AP4E1,THRA,UCHL1,BCL2L13,CLIP2,CLDND1,MFF,STMN4,TUBA1A,ITM2C" Pubmed 25056061 Biological insights from 108 schizophrenia-associated genetic loci. Pubmed 2.06E-20 4.74E-15 6.08E-17 7.86E-16 86 303 "ASPHD1,AS3MT,GRAMD1B,NLGN4X,DOC2A,PITPNM2,ATP2A2,CA8,CACNB2,INA,DGKI,TAOK2,CLCN3,CLU,NGEF,SLC32A1,ANKRD44,RGS6,PLCH2,NCAN,PPP1R16B,CTNND1,TBC1D5,ZNF804A,PARD6A,SGSM2,FAM57B,SEZ6L2,TMTC1,APH1A,PLEKHO1,REEP2,APOPT1,FUT9,LUZP2,GPM6A,GRIA1,GRM3,KCNB1,KLC1,TMEM110-MUSTN1,MAN2A2,MEF2C,MMP16,NEK1,NRGN,HCN1,ZFYVE21,PLCB2,PLCL1,MAPK3,CNNM2,WBP1L,PTN,ZSCAN2,C1orf54,MSANTD2,PBRM1,ATXN7,GALNT10,SHMT2,R3HDM2,CNKSR2,YPEL4,SLC12A4,EFHD1,IGSF9B,RIMS1,TSNAXIP1,GLT8D1,C11orf87,SRPK2,NEK4,SEPT3,PJA1,SMG6,TCF4,SATB2,SLC35G2,CSMD1,CA14,RFTN2,TOM1L2,ADAMTSL3,FXR1,SLC4A10" Pubmed 15572359 Proteomic analysis of in vivo phosphorylated synaptic proteins. Pubmed 5.57E-20 1.28E-14 1.62E-16 2.09E-15 32 52 "AP2A1,PKP4,ARHGEF7,BSN,CACNB4,CAMK2A,CAMK2B,CANX,CTNND2,FAM131B,DBN1,ATL1,EPB41L1,DMTN,SGIP1,AHCYL1,PCLO,MAP2,MAP4,MAPT,MBP,SAMD14,NCAM1,PALM,MAPK3,RTN1,NFASC,EPB41L3,STXBP1,PLCB1,GPRIN3,FMN2" Pubmed 19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Pubmed 7.70E-20 1.77E-14 2.21E-16 2.86E-15 49 118 "ACHE,ADCY2,ADCY8,ADORA2A,BCHE,RGS9,CAMK2A,CAMK2B,CHRM1,CHRM4,CHRNA4,CHRNB2,GRIN3A,DRD1,CACNG2,PPP1R1B,GAD1,GAD2,GLS,GLUL,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,HNMT,HTR2A,HTR5A,MAOB,NTRK2,ZDHHC8,RELN,SLC1A2,SLC1A3,SLC1A6,RIMS1,SNAP25,SYT11,SYT4,SLC17A7,SLC17A6" Pubmed 12421765 Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. Pubmed 2.72E-19 6.25E-14 7.71E-16 9.97E-15 51 130 "DSCAML1,HACE1,SEMA6A,CARNS1,EP400,CACHD1,SHTN1,MADD,SPTBN4,CADPS,DST,SYNJ2,SCAPER,THSD7A,TAOK2,NRXN1,NRXN2,HECTD1,WHRN,SH2B1,SIPA1L1,CNTNAP2,ARHGAP32,FRMPD4,HDAC4,SPOCK2,KIAA0319,MAGI2,FEM1B,RBM12,CELSR3,SORBS1,MEGF10,GRB10,IGSF1,NRCAM,PLXNB3,PTPRN2,MAGI3,CLSTN1,BTBD3,CDK5RAP2,MBD5,MYO16,PDZD2,WDTC1,MCF2L2,EPB41L3,SSPO,FAM208A,PUM2" Pubmed 16632597 Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Pubmed 4.27E-19 9.80E-14 1.20E-15 1.55E-14 30 48 "ASCL1,CDH2,CRMP1,DLX1,ELAVL2,ELAVL4,ETV1,TUBB3,FGF13,NSG2,GAP43,GFRA1,GNG3,STMN2,L1CAM,MAPT,SCG3,TAGLN3,GNG2,SERPINI1,MAPK10,PRPH,RET,SOX2,SOX10,SYT11,PCDHA1,TMEFF2,CADM1,UCHL1" Pubmed 22723691 Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord. Pubmed 4.40E-19 1.01E-13 1.20E-15 1.56E-14 39 80 "ADCYAP1R1,CCKBR,GRIN3A,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GALR1,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TLX1,OPRL1,SSTR1,SSTR2,TACR1,NTSR2,VIPR2" Pubmed 19240061 Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Pubmed 4.40E-19 1.01E-13 1.20E-15 1.56E-14 77 265 "CSMD2,SLITRK1,BBOX1,APP,DNAH17,ADGRB3,MMD2,CACNA1D,CACNA2D1,P2RX6,LONRF2,RAB3C,KMT2C,SLC24A2,ABI3BP,CREB5,ANKRD44,GREB1,CFAP61,CTNND2,DCC,MAGI2,DSCAM,YAF2,ERBB4,EYA1,DLC1,AK8,KIAA1841,FAM19A2,GUCY1A2,IGSF21,TOX2,KLF12,RBPJ,DOCK7,IL6ST,ZNF385B,KCNJ16,MEIS1,MMP16,MN1,NPY,ZNF827,PDE1C,PDE4B,IRX1,PTHLH,PTPN13,PTPRD,SH3TC2,MSANTD2,FIGN,ROBO2,STK32B,SOX6,NTNG1,SLA,SLC12A2,SLC15A2,TMEM132D,RIMS1,MYCBP2,AJAP1,ACSBG1,PLCB1,COBL,WDR7,GALNT17,R3HDM1,CSMD1,PARD3,TNS1,TMEFF2,CELF4,CA10,PCDH15" Pubmed 22939624 Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Pubmed 5.23E-19 1.20E-13 1.41E-15 1.83E-14 95 371 "KLHL32,KLHL13,ALK,CDK10,RIPK1,RGS11,KSR1,BTK,BTRC,DDR1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,TRIM41,CDK11B,RCBTB2,SOCS6,MAP4K4,CSF1R,RGS6,CSNK1E,KCTD8,DAPK3,HP1BP3,FBXO25,RHOBTB1,DMPK,RPS6KL1,SGK2,EGFR,ASB3,TNK2,SRPK3,EPHB1,ERBB2,ERBB4,RPS6KC1,PTK2B,TAOK3,TESK2,FER,GTF2IRD2,FGFR1,FGFR3,FGR,FOXM1,CAMKK2,FYN,DCLK2,LNX1,GRK4,ZBTB49,IRAK3,HSP90AA1,MYLK2,JAK1,KCNA6,KLHL23,MATK,MDM4,STK32C,NTRK2,NTRK3,DDR2,KSR2,CDK18,CDK14,CAMKV,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK4,MAPK7,PTK2,RET,RGS7,ARMC5,NEK11,FBXW7,RPS6KA2,STK32B,SGK1,KBTBD4,FBXW11,TRIM2,TIE1,NR2C2,SGK3,ZNF74,MAP3K12,CAMK1G,GAN" Pubmed 9628581 Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 5.40E-19 1.24E-13 1.44E-15 1.87E-14 45 105 "ADGRB3,SPAG9,LARGE1,CACNA2D2,NRXN3,NRXN1,SUSD5,ATRNL1,GREB1,ST18,ECE2,CCDC144A,KIAA0513,KIAA0586,ARMCX2,JAKMIP2,ZEB2,RASA4,VPS13B,CHST15,NCKAP1,ERAP1,PRRC2B,PCLO,KIF5C,ZNF862,OPA1,MAPKBP1,TNIK,FNBP1,KIF1B,IQSEC2,SPART,COLGALT2,SSPO,NCDN,CEP68,JMJD6,PLCB1,MGRN1,WSCD1,TRIM2,WDR7,FAM189A1,ADAMTSL3" Pubmed 24255178 Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Pubmed 5.89E-19 1.35E-13 1.55E-15 2.01E-14 107 446 "RALGAPA1,ARID1A,AP2A1,AP2A2,AP1B1,AMPD2,LRCH2,PPFIA1,PKP4,APC,DYNLL1,DOCK11,MPDZ,KSR1,DST,MTMR3,TRIM41,ARHGEF2,MAGI1,TJP2,HECTD1,MAP4K4,MAGED1,IFFO1,ANKRD44,CSNK1E,SIPA1L1,PUM1,PPP6R2,FGFR1OP2,GAPVD1,HDAC4,RASSF2,TBC1D5,DBN1,KIAA0753,CEP170,SEC16A,TRAPPC9,PLEKHA1,DMTN,EPS8,DENND4A,BAIAP2,AMOTL2,AGAP3,FOXO3,SORBS1,PNMA2,RAPGEF6,NCKAP1,TNRC6A,RASSF8,DOCK7,USP54,KIF2A,MARK1,MARK3,AFDN,NF1,CDK18,PDCD2,PFKFB2,PIK3C2A,CCSER2,STRN3,PTPN13,DPF2,KIF7,KIRREL1,RTKN,CLIP1,PPP1R9A,R3HDM2,RADIL,CPEB4,UHRF1BP1L,ERC1,SPTAN1,KIF1B,CLASP2,EPB41L3,NEK4,ANKRD28,MTCL1,WWC1,KIAA0930,CLASP1,FRYL,FBXL16,TJP1,R3HDM1,PARD3,TP53BP2,TPM1,WBP2,RUNDC3B,STXBP4,TSC2,TUBB2A,EIF4ENIF1,AMOT,KLC2,RICTOR,SH3GLB2,WNK1,DOCK8" Pubmed 19723784 "Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses." Pubmed 7.26E-19 1.67E-13 1.88E-15 2.43E-14 21 24 "LRBA,SYNPR,SLC32A1,SV2A,DLG4,DNM1,DNM2,GPHN,NBEA,GABRA1,CPLX2,RAB3A,STX1B,RIMS1,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYP,SLC17A7" Pubmed 15146197 Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Pubmed 7.30E-19 1.68E-13 1.88E-15 2.43E-14 201 1103 "CPNE2,GALNT13,ADD2,ADD3,ADORA2A,PWWP2A,FAHD2CP,NLGN4X,ZNF608,HACE1,USP35,BCAR3,ANK2,NT5C3B,ARSE,EIF4G3,ATP1B3,ADAM23,BID,FUBP1,DDR1,CBLN1,CBFA2T2,ARHGEF2,CDH2,SRSF11,TAOK2,CLTB,NIPBL,HOMER3,CNN3,COX4I1,CHD1L,CPS1,CREM,ENTPD4,NCOR2,FEZ1,ARHGEF10,CSNK1G3,VCAN,NCAN,CTNND1,PUM1,RIMS2,RUBCN,MYADM,KATNAL2,KIAA0586,DAPK1,ARMCX2,HEPH,RHOBTB1,DLG3,ABCC5,E2F5,EEF1D,ABI2,LINC00599,TENM1,ELAVL2,PLEKHA1,TNK2,MRNIP,MFSD10,STX2,ERBB2,ERCC2,ZNF391,ETV1,AMZ2,WAC,TBC1D16,ACSL4,TMEM164,UBE2E3,IP6K2,SLC37A3,NOP56,FLYWCH1,TACC2,SPECC1,UFM1,FAM49B,NPTN,TVP23A,ZNF44,NEU3,ARFIP1,WASHC2A,AHDC1,FREM1,OS9,PSRC1,PRRC2B,B4GALNT4,TMEM121B,DIDO1,LINC01089,MAP4K5,C1orf94,ZHX1,PACSIN2,BACH2,HMGCR,HNRNPUL2-BSCL2,FAAP20,ZIC5,USP54,IBA57,ITGAV,KIT,LAMA2,LMO2,SMAD9,ADAM11,MEST,CCDC80,BLOC1S2,SAMD14,HNRNPM,NF1,NFIA,NNAT,NOVA1,ODF2,CHAMP1,OPA1,OPRL1,PALM,PC,PDE4B,HERC2P3,PIK3CD,PKD1,KCTD15,FAT3,PRODH,CYBC1,GON4L,PTN,RIPOR1,TUG1,BSDC1,ZDHHC4,RNF220,RPE,MCMBP,LRRK2,CCDC112,AP1AR,SAFB,TRIM46,MRAS,PUF60,SHMT2,SLC6A9,RADIL,EPC1,ZNF415,SOX2,MYCBP2,ZNF423,ZC3H13,DBNDD2,SPTB,MAPK8IP3,APOM,ZC3H4,VPS13A,ANKRD28,MMS19,UNC5D,CNTN2,AGTPBP1,MGRN1,TCF7,NSD1,C18orf54,ITGB3BP,TJP1,ANKRD24,RBFOX2,TPM1,TUBA3FP,RUSC1,TTC3,RPL7L1,TMEM161B-AS1,BCL2L13,CCDC14,KLC2,PORCN,SLC13A3,ZNF28,ZNF154,EVI5,WIPF2,RTN4,ADAMTS10,RNF146" Pubmed 19274049 "A census of human transcription factors: function, expression and evolution." Pubmed 1.07E-18 2.47E-13 2.74E-15 3.54E-14 174 908 "NR0B1,LCORL,MIER1,ARNTL,ASCL1,NCOA1,BACH1,JAZF1,MYRF,FOXK1,ZBED1,FOXN3,LHX2,VAX2,AHCTF1,ZNF385A,CLOCK,CREM,CREB5,HINFP,ST18,ELMSAN1,ZEB2,ZBTB24,ZC3H11A,ARNT2,DLX1,OLIG1,NR1D2,DMTF1,E2F5,E2F6,EBF1,HEYL,EGR3,EMX2,EN2,OLIG2,ETV1,EZH1,FOXG1,FOXF2,FOXM1,FOXO3,ZBED3,DACH2,TBR1,ZNF44,NKX6-2,ZNF274,GBX2,GLI2,TOX3,ATF7,NR3C1,PRDM5,SOX21,ATOH8,MAEL,TOX2,ZHX1,KLF12,BACH2,MIER3,HLF,HMX1,HNF4G,TLX1,HSF2,IRF8,ZNF181,RBPJ,HES5,INSM1,SMAD1,SMAD9,MEF2C,MEIS1,MEIS2,MITF,MXI1,MYCN,MYT1,RCOR2,NEUROD1,NEUROD2,NFIA,NFE2L2,NFIX,NFYA,NHLH1,NKX2-2,PAX6,PBX1,RC3H2,PRRX1,POU3F2,POU3F4,POU6F1,IRX1,PPARA,SKOR1,PROX1,GON4L,ZSCAN2,DBX2,DPF2,RFX2,RFX3,RFX4,RFX5,ZFHX4,RORB,SOX8,RXRA,RXRG,SALL1,SATB1,SOX6,ARX,PKNOX2,RCOR3,SOX1,MYT1L,TRERF1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,ZHX3,SP2,SP4,NPAS3,CAMTA2,MESP1,CAMTA1,TAL1,TBX15,TCF4,SATB2,CUX2,TCF7,TCF7L2,ZEB1,TCF12,AKNA,HIF3A,ZFPM2,THRA,HEY1,NR2E1,HEY2,ZNF384,NR2C2,TRPS1,UBTF,NSD2,ZBTB14,ZIC1,ZIC2,ZNF711,ZNF708,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZBTB38,MEIS3,PRDM2,CERS6,ZNF30" Pubmed 10817752 "Cadherin superfamily genes: functions, genomic organization, and neurologic diversity." Pubmed 1.18E-18 2.72E-13 2.99E-15 3.86E-14 37 74 "PCDH10,PCDHGB4,PCDH17,PCDH11X,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 23382691 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. Pubmed 1.46E-18 3.36E-13 3.66E-15 4.72E-14 64 199 "FMNL2,GPR158,TBC1D14,LRRC4C,CADPS,CACNA1I,CACNA1E,MAGI1,RAB3C,CNTN1,CNTNAP2,ARHGAP24,CTIF,ELMO1,DOCK2,DPP6,DYRK1A,FRY,KMT5B,EPB41L2,SORBS1,NRG3,MEGF10,DNER,GFRA1,GPM6A,GRM3,PTPRT,BACH2,SHISA6,PLD5,IL6ST,PIK3AP1,SYT9,LRP1B,MGAT3,MX1,ALDH1L2,SNTG1,CDK18,JAKMIP1,VPS13C,MDGA2,PEX5,CCDC40,ROBO2,HUNK,SBF1,LRRTM4,ST6GAL1,SEPHS1,SLC8A3,TMEM132D,SLIT1,SMARCD3,ZNF423,MPRIP,TEK,CDH22,PRRT1,CSMD1,VAV2,PDSS2,DNAH10" Pubmed 24613359 Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Pubmed 2.26E-18 5.20E-13 5.59E-15 7.23E-14 30 50 "SLITRK1,ADGRB1,ADGRB2,ADGRB3,NRXN1,NRXN2,SLITRK5,DLG2,DLG4,GPHN,GAD1,GRIA1,LRRTM3,LRRTM1,NTRK2,NTRK3,LRRN3,LRRTM4,SLITRK3,NLGN1,CLSTN1,CLSTN2,SYN1,SYP,ADGRL3,LRRC24,LRTM2,FLRT2,FLRT1,SLC17A7" Pubmed 16385451 A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Pubmed 2.34E-18 5.37E-13 5.71E-15 7.38E-14 101 416 "AS3MT,ADARB2,ADD3,SORCS1,GPR158,ANK3,ANXA7,GPAM,SHTN1,SEMA4G,BTRC,CACNB2,CAMK2G,CH25H,INA,NEURL1,LGI1,ARHGAP22,ACBD5,SEC31B,CREM,ATRNL1,CALY,SPOCK2,RHOBTB1,FAM107B,CHRDL1,ABI1,CNNM1,OPTN,CDHR1,CHST15,TACC2,SORBS1,ADGRA1,PHYHIPL,GAD2,GFRA1,POLL,ATE1,ARHGAP19,HPSE2,KNDC1,USP54,ITIH2,KCNMA1,HECTD2,ARHGAP12,PIK3AP1,ZFYVE27,JAKMIP3,CTNNA3,MXI1,SFR1,NODAL,VWA2,PFKFB3,PFKP,CCSER2,CNNM2,PSD,WBP1L,PTPRE,CRTAC1,RET,RGR,RGS10,SEC61A2,MCMBP,KCNIP2,CPEB3,HKDC1,ZNF365,RUFY2,SEPHS1,TET1,SLIT1,EPC1,OGDHL,SORCS3,CABCOCO1,ZCCHC24,ZSWIM8,UNC5B,LHPP,PBLD,MMS19,DNMBP,TCF7L2,ZEB1,SIRT1,TLL2,PARD3,KAT6B,DNAJC12,PCDH15,FAM13C,MARCH8,JMJD1C,ZNF248,SLC39A12" Pubmed 10716726 Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Pubmed 3.87E-18 8.89E-13 9.36E-15 1.21E-13 38 80 "PCDH10,PCDHGB4,CELSR3,PCDH17,PCDH11X,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 14691545 Transcriptome analysis of mouse stem cells and early embryos. Pubmed 5.89E-18 1.35E-12 1.41E-14 1.82E-13 77 276 "NCKAP5,TAOK1,ALS2,CDC14B,ATP2B1,DOCK11,CACNA1G,CAPN3,LDB2,CCPG1,CNTN1,COL4A5,LETMD1,HINFP,LRIG1,PDE4DIP,ERC2,PUM1,DCAF4,ARHGAP32,DCC,HP1BP3,MAGI2,SNAP91,DLG3,FARSB,EDNRA,EIF4G2,ELAVL4,POLK,STAU2,ZNF274,USP19,FERMT2,NR3C1,GSN,HPSE2,RBPJ,ITGA7,IPO5,MBNL1,TM6SF1,CD200,PLEC,EPB41L4B,BCAS3,CYBC1,DEF8,MTMR10,RAP1GDS1,PBRM1,LGR4,NCBP3,ZNF821,SGK1,KIF16B,FBXO11,SLC12A2,SCMH1,OGDHL,SMARCE1,USP33,LARP4,RGL1,ZC3H4,SYT4,PJA1,DOCK9,ZNF106,NACC2,TMPO,CABIN1,ZMYND8,P2RY12,ZIC1,WNK1,ADAMTS9" Pubmed 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 6.21E-18 1.43E-12 1.47E-14 1.90E-13 123 565 "GPRIN1,NDRG2,FMNL2,ELFN2,ADD1,ADD3,ESYT2,KIDINS220,LRRC7,ANK3,PKP4,SHTN1,ARHGAP5,NUMB,ATP2B1,BCL2L2,DST,SYNJ1,SYNJ2,CAST,SCARB1,SEPT7,LRRFIP1,MAGI1,NUMBL,EPS15L1,TJP2,CNN3,SLC4A7,FAM171B,CTNND1,USP6NL,ARHGAP32,GAPVD1,ZFYVE16,IST1,SIRPA,DBN1,ABI1,EEF1D,SH3GLB1,EGFR,EIF4G1,EIF4G2,EIF5,PLEKHA1,EPB41,EPB41L1,ERBB2,RACK1,SEC24B,BAIAP2,NOP56,SORBS1,SPECC1,PDLIM5,ARFGAP2,GAB1,SEPT9,ARFIP1,GOLGB1,PACSIN2,ATXN2L,HNRNPK,AGFG1,IL6ST,KTN1,MAP4,MARK3,AFDN,DBNL,MYO6,PCMT1,OLA1,PFKP,ANLN,CCSER2,XRN1,PKM,PLEC,EPB41L4B,SH3KBP1,PKN2,RDX,RPL15,PUF60,FERMT1,MAGI3,ABLIM3,EPN2,SHANK2,SLC12A2,INAVA,LIMCH1,SNAP25,FAM126B,ERC1,SPTAN1,ITPRID2,EPB41L3,ERBIN,MPRIP,NSFL1C,EHBP1,DOCK9,ARHGEF12,TJP1,TMPO,PARD3,TP53BP2,TPD52,TPD52L2,UBC,KLC2,SH3GLB2,SLC38A1,CIAPIN1,NAV2,WIPF2,RTN4,NUP214,TTC7A,NHSL1" Pubmed 10835267 Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. Pubmed 6.53E-18 1.50E-12 1.53E-14 1.98E-13 37 77 "PCDH10,PCDHGB4,PCDH17,PCDH11X,PCDHGC3,PCDH8,PCDH9,PCDH18,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PCDH20" Pubmed 27889896 Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice. Pubmed 6.89E-18 1.58E-12 1.60E-14 2.07E-13 43 102 "NDRG3,NDRG2,ADD1,AP1B1,PPFIA2,PPFIA1,PPFIA3,NUMB,SLC4A4,ATP2A2,ATP2B3,WASF1,CAMK2D,ENTPD2,NRXN1,ERC2,CTNND2,C2CD2L,DTNA,ATL1,CAMSAP1,AGAP2,FERMT2,LNX1,GRIA2,KCNJ10,KIF5A,VWA5A,CDK14,NOMO2,PPP3CA,PRKAR1B,PRKCG,KLHL11,HSPA4L,SLC1A3,SLC6A1,SPHKAP,ERC1,PHLDB1,KAZN,HEPACAM,TRIM9" Pubmed 24324551 Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. Pubmed 7.40E-18 1.70E-12 1.70E-14 2.20E-13 50 134 "ASIC2,ADARB2,GPR158,SMIM29,LRRC4C,ZFYVE28,DIRAS1,KALRN,SLC5A11,DLGAP1,SUMF2,RGS6,LRIG1,CTNND2,DOCK4,HDAC9,DGKB,MAGI2,DLG2,HS3ST4,DYNC1I1,LOC101928524,FDFT1,CHL1,FAM184B,ALDH1L1,GRIA4,ALDH1L1-AS2,TJAP1,SYT9,MITF,NCAM1,NELL1,PTPRD,ATXN1,MRAS,SLC8A1,SPTB,NPAS3,RAP1GAP2,KAZN,CAMTA1,PMS2CL,TIAM1,ASXL3,CSMD1,RUNDC3B,EMX2OS,WIPF2,SMIM8" Pubmed 15146195 Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Pubmed 8.73E-18 2.01E-12 1.99E-14 2.57E-13 27 42 "SPARCL1,APBB1,APLP1,APP,ATP1A1,ATP1A3,ATP2B2,CADM3,ADAM23,CLU,CNTN1,NTM,DNM1,DPP6,DPYSL2,APH1A,L1CAM,LSAMP,MAG,MBP,MOG,NCAM1,NCAM2,OPCML,PLP1,CLSTN1,STXBP1" Pubmed 23431145 The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Pubmed 9.95E-18 2.29E-12 2.24E-14 2.89E-13 40 90 "NRP2,CCK,CDH8,CDH10,ZNF521,NCOR2,CRYM,MICAL2,PLXNA4,DCT,SV2B,EMX2,ETV1,PPP1R1B,FGFR3,CAP2,TBR1,DNER,ALDH1L1,GNAL,UBE2QL1,LRRTM3,KCNQ3,LMO1,FGFBP3,MEST,MMP17,NCAM2,PAX6,FAT3,PTPRO,ROBO1,ROBO2,RORB,BCAN,TCF4,HEY1,PRDM8,NAV2,ACTR3B" Pubmed 10231032 Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.07E-17 2.47E-12 2.39E-14 3.09E-13 43 103 "MYRF,THSD7A,CAMK2A,TBRG4,NRXN2,CORO2B,AMOTL2,SEPT9,CIT,HPS5,PADI2,NLGN4Y,ZFP30,FRMPD1,CPEB3,NTNG1,FNDC3A,R3HDM2,DZIP1,ANKRD6,WDR37,RPH3A,BTBD3,MAST1,MYH15,FAIM2,PALLD,EPB41L3,RGL1,SYNE2,VPS13A,DNAJC9,DNMBP,KIAA0930,RPGRIP1L,PSD3,SIK3,DNAH7,DICER1,TLL2,SEZ6L,ZKSCAN5,NAV3" Pubmed 15217342 The synaptic vesicle cycle. Pubmed 1.62E-17 3.71E-12 3.57E-14 4.61E-13 23 31 "SYN3,PPFIA4,PPFIA2,PPFIA1,PPFIA3,BSN,RIMS4,ERC2,RIMS2,RIMS3,SV2B,SV2A,CPLX2,CPLX1,PCLO,STXBP5,RAB3A,RIMS1,SNAP25,STXBP1,SYN1,SYN2,SYP" Pubmed 9205841 Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 1.66E-17 3.81E-12 3.63E-14 4.69E-13 43 104 "MADD,SYNJ2,MTMR3,DCLK1,AKAP6,CLOCK,ENTPD4,ARHGEF10,ERC2,CTNND1,RIPOR2,SNPH,FRMPD4,ZFYVE16,PLEKHM1,RUSC2,KIAA0319,ARNT2,SEC16A,DNAH9,SUGP2,EPB41L1,EZH1,SRCAP,PRUNE2,DIDO1,IGSF1,MYO6,NRCAM,PTPRN2,CHD9,RIMS1,PDZD2,HECW1,NACAD,ANKRD28,MCF2L,ARHGEF12,DAAM2,RIMBP2,KAT6B,CABIN1,WNK1" Pubmed 24448406 The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Pubmed 1.95E-17 4.47E-12 4.22E-14 5.45E-13 21 26 "CASK,CADM3,PTBP2,CAMK2A,CAMK2B,MAGI1,DBN1,DLG4,DNM1,DNM2,GPHN,ERBB4,GABRG2,GRIA2,KCNQ2,PPP3CA,NLGN1,KIF21B,SYP,ARHGEF12,PITPNB" Pubmed 9872452 Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 3.04E-17 6.99E-12 6.53E-14 8.44E-13 42 101 "PLEKHG5,ADGRF5,ATP1A2,DST,BAIAP3,ZBED1,NRXN3,SLC4A8,MICAL2,PHF14,RIMS2,FAM131B,DOCK4,HDAC9,ARHGAP32,TCAF1,TOX,MATR3,DGKB,SPATA2,KIAA0753,DDX46,RHOBTB1,SACS,SV2B,SV2A,KBTBD11,RBM12,CAMKK2,TMCC1,KDM3A,KDM4C,ZNF423,DDN,NFASC,TAB2,ATP10B,MTCL1,DDHD2,ADGRL3,SMG6,SYNE1" Pubmed 20412781 Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Pubmed 3.56E-17 8.18E-12 7.57E-14 9.78E-13 147 744 "RBM10,KDM5D,ARID1A,MTA3,NR0B1,MRTFA,ZNF687,LCORL,ARNTL,NCOA1,BACH1,SCAPER,JAZF1,FOXK1,LDB2,CERS5,ZNF445,TBPL1,AHCTF1,ZFP28,ZNF385A,CLOCK,CREM,HINFP,NCOR1,PHF14,TOX,PHF19,ZBTB24,ARNT2,OLIG1,NR1D2,DMTF1,E2F5,E2F6,EBF1,PHF20L1,MBNL2,PLXNC1,ING4,ETV1,FOXM1,FOXO3,ANKFY1,PDLIM5,ARFGAP2,ABLIM2,ZNF512,ZMYND11,SALL3,ZNF274,GBX2,SRCAP,BRD8,DBF4,GLYR1,TOX3,ZNF638,ATF7,DIDO1,NR3C1,PRDM5,ZNF496,KAT7,SOX21,MAEL,KLF12,BACH2,IRF8,ZIC5,RBPJ,LIMS1,LMO1,SMAD1,MBD1,MBNL1,MEIS2,MYCN,MYT1,RCOR2,NEUROD1,NFE2L2,NFYA,PAX6,ZNF655,ZNF426,PRRX1,ING3,PPARA,ROGDI,ZDHHC14,DPF2,RFX2,RFX3,ZDHHC4,PBRM1,ZNF354C,RXRA,SALL1,SATB1,ATXN1,HES6,SOX6,DZIP1,LIMS2,ZNF334,BTBD7,ZKSCAN3,SMARCE1,KDM4B,SOX1,MYT1L,TRERF1,SOX2,SOX3,SOX5,SOX15,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,RBM26,POGZ,JMJD6,TAF6,TBX15,TCEA1,TCF4,SATB2,CUX2,TCF7L2,ZEB1,TCF12,ZMAT3,THRA,HEY1,NR2E1,ZNF346,TRPS1,ZMYND8,UBTF,ZFP37,ZFP41,ZDHHC20,DPF3" Pubmed 16944949 Identification of 14-3-3epsilon substrates from embryonic murine brain. Pubmed 3.81E-17 8.76E-12 8.03E-14 1.04E-12 48 129 "SYN3,ACLY,OGT,LRCH2,MARK4,KSR1,BRSK2,CBR1,INA,DCLK1,ARHGAP33,DLGAP3,CLTC,HOMER3,ERC2,CTNND1,RIMS2,RIMS3,GIT2,DBN1,CEP170,SRGAP3,DYRK1A,EEF1A2,BAIAP2,MSANTD4,BRSK1,DCLK2,DOCK7,KIF5A,MARK1,MARK3,GIT1,DBNL,NF1,ATAT1,SFPQ,R3HDM2,WDR37,CCDC88A,KIF21B,ERC1,MPRIP,SYN1,SYN2,CRTC1,TSC1,DOCK8" Pubmed 22802532 Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Pubmed 6.31E-17 1.45E-11 1.32E-13 1.70E-12 25 38 "ACTN1,MTA3,ANK3,NUMB,ATM,PTBP2,CAMK2B,CAMK2G,RAB28,DBN1,DNM1,ERBB4,GLUL,NOVA2,PAX6,GPR85,PPP3CB,PXK,DZIP1,SPHKAP,SNAP25,MCF2L,PUM2,TPM3,PITPNB" Pubmed 16537572 Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Pubmed 8.43E-17 1.94E-11 1.75E-13 2.25E-12 62 203 "APAF1,CHRD,BMP7,BMPR1B,CALB1,SLC25A14,NOG,CNR1,PICK1,COL9A1,COL9A2,COL11A2,PNKD,HAPLN1,VCAN,NCAN,DGKG,SPOCK2,SPOCK3,NR1D2,FABP7,RACK1,FGFR1,FGFR3,BAIAP2,CSPG5,DLL3,TBR1,SYT17,GBX2,ADAMTS8,PACSIN2,HAPLN2,MATN2,MATN3,NCAM1,NCAM2,NELL1,NEUROD2,PAX6,SEMA5B,PKD1,PACSIN1,MED1,PRKCG,RELN,LAMA1,PTHLH,PTH1R,CRTAC1,BAALC,S100B,HKDC1,SCN3B,THSD1,NCDN,STX1A,THBS4,TLL2,NPDC1,ZBTB16,TFIP11" Pubmed 16919269 A global genomic transcriptional code associated with CNS-expressed genes. Pubmed 1.04E-16 2.39E-11 2.14E-13 2.76E-12 79 301 "ADCYAP1R1,SORCS1,GRAMD1B,APAF1,SEMA4G,ARHGAP5,MARCH3,ADAM23,NRP2,BTRC,CLDN10,LRBA,CDH8,L3MBTL4,CHN1,NRXN1,PCYT1B,RIMS2,SNPH,DCT,ZEB2,EBF1,EDNRB,HIPK3,ELAVL4,SPEG,ZIC4,DLC1,GCNT2,POLL,DCLK2,GRIA2,IGSF1,METTL21A,KCNA1,EFHB,MEIS2,MITF,PAX6,PBX1,GPR85,OLA1,KCTD15,FTO,PROX1,APTX,CNTLN,PTCH1,PTPRE,PEX2,OXR1,FIGN,RGS4,ZFHX4,SALL1,SATB1,SGK1,ARX,CPEB3,NLGN1,ST8SIA1,DZIP1,SORCS3,SOX2,SOX5,SOX11,DOK5,NPAS3,GSE1,TCF4,TCF12,ZFPM2,AKTIP,GALNT17,TMPO,TRPS1,TTC3,ZIC2,SLC4A10" Pubmed 9371744 Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Pubmed 1.43E-16 3.28E-11 2.90E-13 3.75E-12 62 205 "ABR,AGT,SPARCL1,ANXA7,APBB1,LDHD,CDK5R1,CBLN1,DLGAP1,NGEF,CNTN1,MAGED1,COX4I1,ZFP28,CRMP1,RNF14,LRIG1,PDE4DIP,CST3,RIMS2,TMEM170A,SIRPA,PLPPR4,SPEG,TUBA1B,TUBB4A,RACK1,AHCYL1,ARPP21,GP1BB,GPR12,KIF5A,MAG,MBP,MPP2,NPTX1,PKM,PRKAR1B,MAPK3,SNRK,PTK2,SGSM1,FOXRED2,SARS,CCDC92,SLC1A3,RUFY2,TTC17,SNRPN,UNC5B,DBNDD2,TSPYL2,DDN,VAMP1,SYN2,TCF12,TUBB2A,UBE2H,NDRG4,TUBA1A,RGS7BP,NHSL1" Pubmed 15144186 Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Pubmed 1.58E-16 3.64E-11 3.19E-13 4.12E-12 48 133 "CDK13,PDE8B,DDX3Y,RIPK1,ARHGEF7,SPAG9,EPS15L1,TJP2,ARHGEF6,SLC4A7,USP6NL,ZFYVE16,TBC1D5,GIT2,DOCK2,RBM12,EGFR,SRRM1,FCGR3A,DCTN2,FYB1,FYN,ARPP21,RAPGEF1,ATXN2L,ARHGAP12,MAP4,AFDN,DBNL,OPA1,PDPK1,SH3KBP1,MAPK3,PTPRB,KIRREL1,AP1AR,TNIK,FNBP1,ZC3H13,SRPK2,ERBIN,EHBP1,DMXL2,ICAM5,R3HDM1,PARD3,TP53BP2,GOPC" Pubmed 17353931 Large-scale mapping of human protein-protein interactions by mass spectrometry. Pubmed 1.94E-16 4.46E-11 3.88E-13 5.02E-12 217 1284 "ACLY,LRRC7,SPOP,BCAR3,UNC79,OGT,ALS2,BCAS1,ARHGDIA,ARRB1,RGS20,ARRB2,CCAR2,DYNLL1,EIF4G3,ATP1B3,ATP2A2,CFLAR,ARHGEF7,FUBP1,NAE1,FOXK1,CALM1,CAMK2A,CAMK2B,CAMK2D,SPAG9,RUNX1T1,CBR1,CCNH,AIFM1,CDK11B,LRBA,ARHGEF2,SEPT7,CDC25B,CDC42,MAGI1,CDO1,TBRG4,COPB2,SRSF11,CNOT8,KMT2C,CLTC,TJP2,SLC4A7,MAGED1,TBPL1,COX4I1,CDC42BPB,CSNK1E,OSBPL3,DOCK4,GAPVD1,HDAC4,MATR3,DGKB,GIT2,DBT,DCTN1,ZBTB24,MAGI2,G3BP2,DLG3,PDCD6IP,DYRK1A,EEF1A2,RASGRP1,EEF1D,KMT5B,ASB3,EIF4G1,EIF4G2,COPS4,EPB41,EPB41L2,SRRM1,DENND4A,FDFT1,BAIAP2,SYNCRIP,NOP56,NELFCD,SORBS1,SMC2,UFM1,PNMA2,AP4B1,NEURL4,CAB39,FAM120B,NEK6,NCKAP1,IQGAP2,MTHFD2,C15orf41,INPP5K,GART,MALT1,TTBK1,RNPS1,HTATSF1,GNAS,NUDT21,EML4,GSN,FAM107A,RASSF8,DDX19B,GABARAPL2,SMAP1,ICA1,JAK1,KHK,KIF5C,KLC1,LIG4,LIMS1,MARK3,MEST,MKLN1,AFDN,MOV10,GIT1,DBNL,MTR,MYH7,MYO6,HNRNPM,NASP,OGG1,OPA1,PCMT1,PFKFB3,FAM98B,OLA1,PFKP,CDK14,PIK3R1,STRN3,TNPO2,PPM1B,PRKAB2,PSMA6,SNRK,PSMD13,PTK2,PYGM,PLEKHB2,RAD51D,ATG16L1,RASGRF2,RGS10,CCDC82,RPL38,KCNIP2,SARS,ATXN2,TRA2B,HSPA4L,PUF60,SGK1,SHMT2,CNKSR2,PAAF1,PPP4R3A,RADIL,SIRT2,CDK5RAP3,EFHD1,SMARCA4,RIMS1,SNRPN,SON,EMC1,MYCBP2,ERC1,KIF1B,CDK19,SRPK2,CLASP2,TROVE2,EPB41L3,MPRIP,SEPT8,TTBK2,GANAB,MMS19,FBXW11,KIAA0930,CLASP1,FRYL,CRB1,AKTIP,TIAM1,PARD3,TPM3,TSC1,TSC2,RPRM,RPL7L1,CLEC2L,KLC2,XRCC4,SPIRE1,CAB39L,NELFE,PARP11,RTN4,PAK5,HNRNPA3,ACTR3B,JMJD1C,FRMD6,LAS1L,JPH3" Pubmed 19571125 Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. Pubmed 2.89E-16 6.64E-11 5.67E-13 7.33E-12 21 28 "ASCL1,CALB2,LDB2,LHX2,OLIG1,ENO2,ETV1,TBR1,GAD1,GFAP,MBP,NEFH,PAX6,PLP1,RELN,FEZF2,RORB,ARX,SATB2,CUX2,SLC17A7" Pubmed 19208628 The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. Pubmed 2.89E-16 6.64E-11 5.67E-13 7.33E-12 21 28 "LRRC7,ARHGEF7,CAMK2A,DLGAP1,CTNND1,CTNND2,DLG4,SHANK1,ABI1,EPS8,CACNG2,BAIAP2,GRIA1,GRIK1,GRIN1,SYNPO,MAP2,DBNL,SHANK2,SPTAN1,ARC" Pubmed 19736351 "Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation." Pubmed 3.90E-16 8.96E-11 7.53E-13 9.73E-12 22 31 "NLGN4X,DOC2A,DPP10,APBA2,CASK,DLGAP2,NRXN1,DLG2,ERBB4,GABRA2,GABRA4,GABRA5,GABRB3,GABRG1,GRM7,IL1RAPL1,MAPT,PRODH,PTK2,NLGN1,SLC1A3,ST7" Pubmed 22357600 The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Pubmed 3.90E-16 8.96E-11 7.53E-13 9.73E-12 22 31 "ADD3,CASK,CADPS,FUBP1,CACNA1B,CACNA1D,CALB1,CHD5,DMTN,DKK3,GABRG2,KCND3,KCNQ2,NRCAM,PBRM1,SCN8A,SNAP25,EPB41L3,CAMTA1,RBFOX2,LRP8,CSDE1" Pubmed 17634366 Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. Pubmed 4.12E-16 9.46E-11 7.88E-13 1.02E-11 53 161 "CNTNAP1,ATP1A1,ATP1A2,ATP1A3,CANX,INA,SEPT7,CLTC,CNTN1,CNRIP1,DNM1,DPYSL2,PDCD6IP,EEF1A2,ENO2,TUBA1B,TUBB4A,ATP5PD,GFAP,GLUL,GNAO1,TPPP,GSTM5,HBA1,HSP90AA1,IDH3A,MAG,MBP,MOBP,MOG,TAGLN3,NCAM1,NEFH,CLDN11,PKM,PLP1,SEPT4,PACSIN1,RDX,MYH14,SIRT2,NAPB,SNAP25,SPTAN1,NFASC,SEPT8,STXBP1,PLCB1,SYN1,SYN2,UBC,UCHL1,TUBA1A" Pubmed 16107646 Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Pubmed 4.42E-16 1.02E-10 8.39E-13 1.08E-11 51 151 "NCKAP5,FMNL2,LRCH2,SHTN1,DCLK1,QKI,CNN3,SLC4A7,ST18,MATR3,DCC,FAM107B,CDON,GNE,DNM1L,ATL1,FEM1B,PHF20L1,TMEM74,MEX3B,FOXG1,STAG2,GABRG2,TOX3,ZNF638,GRIK1,SOX21,PSIP1,ARHGAP12,SMAD1,MEST,KITLG,POC1B,PCDH18,TNPO2,POU3F2,PBRM1,PCMTD2,SFPQ,TRA2B,WDR37,ATF7IP,SOX5,SOX11,THSD1,ERBIN,EHBP1,SIRT1,CRB1,TMPO,TP53BP1" Pubmed 15324660 "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." Pubmed 5.80E-16 1.33E-10 1.09E-12 1.41E-11 70 256 "ADORA3,PPFIA1,ALS2,USP37,SHROOM2,ARHGEF7,CAPN3,ARHGEF2,NUMBL,CLTC,TJP2,HECTD1,ARHGEF6,SLC4A7,OSBPL3,CTNND1,DOCK4,GAPVD1,HDAC4,GIT2,CEP170,DYRK1A,SRRM1,DENND4A,TUBB4A,PRMT5,FER,BAIAP2,FOXO3,RAPGEF6,NCKAP1,RNPS1,PARD3B,RASSF8,DOCK7,KLC1,MARK3,AFDN,GIT1,HNRNPM,PFKFB2,PIK3R1,JAKMIP1,MAPKAP1,RGS12,TRA2B,PUF60,EPN2,RADIL,SON,MYCBP2,ERC1,KIF1B,EPB41L3,MPRIP,KIAA0930,CLASP1,CRTC1,FRYL,TIAM1,PARD3,TP53BP2,TSC1,TSC2,TUBB2A,UBC,KLC2,WNK1,TUBA1A,FRMD6" Pubmed 20195357 A comprehensive resource of interacting protein regions for refining human transcription factor networks. Pubmed 6.44E-16 1.48E-10 1.20E-12 1.56E-11 58 189 "KIDINS220,ANK2,ANK3,ANXA7,APP,KIF1A,CACNA1B,SRSF11,CHGB,CLU,STOML1,CABP1,NCOR2,FEZ1,ERC2,KIAA0408,MATR3,DCTN1,EEF1D,OPTN,COPS4,TUBA1B,TUBB4A,TAOK3,KIAA1109,KHDRBS3,MPP6,GABBR1,TCERG1,CBX1,GNAS,ATF7,NR3C1,HMGB1,HSP90AA1,MAP2,TCEAL5,NAP1L1,NEFM,PKM,SCHIP1,PKIA,CYBC1,SYTL2,OCIAD1,RGS3,RYR3,LINC00461,CLSTN1,ZC3H13,SYT1,TAF9,CAMSAP2,TP53BP1,UBTF,ZNF24,TUBA1A,GOPC" Pubmed 20114047 Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes. Pubmed 7.68E-16 1.76E-10 1.42E-12 1.84E-11 28 51 "AP2A1,AMPD2,ATP1A1,ATP1A2,ATP1A3,CLTC,DNM1,TNK2,VTI1B,NCKAP1,TUBGCP4,GNAO1,GPM6A,KCNMA1,KIF5C,MAP6,STX1B,NAPB,SNAP25,STX1A,STXBP1,SYP,KIAA1107,TUBB2A,KLC2,SLC30A3,TUBA1A,ST8SIA2" Pubmed 25826454 Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Pubmed 8.09E-16 1.86E-10 1.49E-12 1.92E-11 46 128 "DSCAML1,LRFN2,ALCAM,LRFN1,IGDCC4,CADM3,VSTM2A,JAM2,IGLON5,CNTN1,IGDCC3,NECTIN3,CSF1R,LRIG1,BOC,DCC,NTM,CDON,DSCAM,OLIG2,SPEG,FLT1,CHL1,MALT1,ADGRA3,PTPRT,LINGO1,NEGR1,NCAM2,LRIT2,NRCAM,IGSF11,CNTN3,PRTG,LRRN3,KIRREL1,LRFN5,LRRC4,CNTN2,TEK,TIE1,ICAM5,LRRC24,TRIO,CADM1,CADM2" Pubmed 29513653 Developmental diversification of cortical inhibitory interneurons. Pubmed 1.09E-15 2.51E-10 1.98E-12 2.55E-11 36 83 "TTYH1,PCDH10,ASCL1,RUNX1T1,LHX2,SLC32A1,CST3,DBI,TIAM2,DLX1,EBF1,EDNRB,OLIG2,FGFR3,GAD1,GAD2,SALL3,CSDC2,SOX21,HES5,INSM1,LMO1,MEF2C,MYT1,NCAM1,NFIA,NNAT,PAX6,POU3F4,PROX1,PTPRZ1,PBRM1,ARX,SLC1A3,SOX11,NPAS3" Pubmed 10862698 Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Pubmed 1.09E-15 2.51E-10 1.98E-12 2.55E-11 36 83 "ACTN2,BSN,CAMK2A,CAMK2B,INA,CDH2,DLGAP1,CLTC,AKAP5,APPL1,CTNND1,DLG2,DLG3,DLG4,DNM1,PTK2B,GRIN1,GRIN2D,GRM1,CIT,MAP2,NF1,NOS1,PIK3R1,PPP3CA,PPP5C,PRKCB,PRKCG,MAPK3,SHANK2,SPTAN1,ARC,TJP1,TP53BP1,KLC2,TUBA1A" Pubmed 15747579 Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Pubmed 1.46E-15 3.35E-10 2.62E-12 3.38E-11 74 284 "VWA5B2,ADAR,AP1B1,KIAA1324,LTBP4,LCORL,APP,SLC7A14,ASPH,STX16,OSGIN2,BTRC,HIP1R,CLTC,TJP2,SLC4A7,SLC4A8,CREM,SIPA1L1,CNTNAP2,RUBCN,PLEKHM1,WDR20,ABI1,USH1C,SGK2,STARD3NL,PAN3,FECH,MED12L,FGF12,SEC23B,FLT1,UFM1,USP21,KIAA1841,IGSF5,USP19,GNAO1,PRRC2B,RAPGEF4,FICD,PSIP1,HECTD2,RTL5,NTRK2,OXTR,PFKFB3,SGSM1,DGLUCY,FOXRED2,SARS,ATXN7,RADIL,KDM4B,SP2,CAND2,LARP4,NEK4,JMJD6,MTCL1,EXOC7,DNMBP,AGTPBP1,TJP1,BHLHB9,PPIL6,SLC35A4,ZNF24,ZFP41,FMN2,MEIS3,JMJD1C,SLC4A10" Pubmed 22558309 Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks. Pubmed 1.73E-15 3.98E-10 3.08E-12 3.98E-11 42 111 "AGT,LTBP4,AMPH,PPFIA2,DST,SYNJ2,DLGAP2,DLGAP1,EPS15L1,CLTC,PDE4DIP,DNM2,PDCD6IP,CEP85L,DISC1,AHDC1,GOLGB1,HNRNPK,AGFG1,GAREM2,ITPKA,PIK3AP1,MBNL1,PDE4D,PIK3R1,SH3KBP1,SPDL1,ITSN1,KIF16B,EPN2,FNBP1,ERC1,SYN1,TACC1,ZFPM2,TIAM1,NR2C2,TRIO,WIPF1,CLIP2,SYNC,WIPF2" Pubmed 16303743 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Pubmed 1.81E-15 4.16E-10 3.20E-12 4.14E-11 97 430 "SYS1,C1QTNF1,ADGRF5,C1QTNF3,SEMA6A,PI16,CHID1,SLC2A11,ADAM15,PROM1,ENTPD6,ADGRG1,MS4A7,STOML1,FADS2,TMEM184B,SUMF2,CS,MYADM,RRP7BP,LYPD1,SV2A,SEZ6L2,SIDT2,APH1A,PCOLCE2,ELN,SLC43A2,RTN3,ARMCX1,TUBB4A,FCGRT,C2orf88,POMT1,ATP2C1,ERGIC3,DLL3,SARAF,GHDC,LYVE1,GPR19,GPR34,PLPP7,SPACA9,CACFD1,TMEM25,MFSD2A,SLC2A6,IGSF21,MAN1B1,VSIG4,ELOVL5,SCIN,FGFBP3,CLEC18A,AQP11,MATN2,LDLRAD3,KCTD6,CD200,SCG3,PAX6,NLGN3,RETREG2,DRAM2,SLC26A11,SYTL2,PIGG,TMEM145,TTC13,PRRT2,WLS,DRAXIN,EMC1,SPP1,DBNDD2,SYT11,ALG1,CYB561A3,SPX,LEFTY2,TMEM9,RELL2,LRRC8A,RUSC1,HSPBP1,TMEFF2,CADM1,RPRM,CLDND1,ATP6V0E2,SLC38A1,RGMA,GDPD5,LMAN2L,TMEM178A,ITM2C" Pubmed 22589738 Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. Pubmed 1.84E-15 4.23E-10 3.23E-12 4.17E-11 58 193 "ADCY2,ZNF608,ZFAT,BACH1,LARGE1,CP,HAPLN1,CRY2,CNTNAP2,TOX,POM121,PDCD6IP,SNX29,EPHB1,HSPA12B,FKTN,MAD2L2,C1orf61,PDLIM5,NSG2,DKK3,SALL3,PCDH17,LUZP2,DCLK2,GRM7,GUCY1A2,BACH2,NEGR1,HTR2A,SLC6A17,ITPKB,KCND3,LYPLAL1,WDR49,NCAM2,KSR2,OPCML,SNX10,FTO,PSAT1,RORB,TNFRSF19,FAM81A,LHPP,CLSTN2,NKAIN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,CADM2,ADAMTS9,DNAH10" Pubmed 10380929 A striking organization of a large family of human neural cadherin-like cell adhesion genes. Pubmed 2.29E-15 5.27E-10 3.99E-12 5.16E-11 33 72 "PCDH10,PCDHGB4,CELSR3,PCDHGC3,PCDH8,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 11230163 Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Pubmed 2.35E-15 5.40E-10 4.06E-12 5.25E-11 32 68 "PCDH10,PCDHGB4,PCDHGC3,PCDH8,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 11256614 Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. Pubmed 4.30E-15 9.88E-10 7.37E-12 9.52E-11 110 523 "ABAT,ACADM,RBM10,TKTL1,NDRG2,INTS2,SYT13,BIN1,APOC1,USP37,CCAR2,GPC2,NFS1,CDC27,TBRG4,CNOT8,PPT2,FBXO7,PNKD,MROH8,PNPLA8,ARHGAP24,AIF1L,DBN1,ELMO1,TMEM130,SV2A,CCDC3,RAB39B,FAM57B,DNAJB6,GOLT1B,COQ7,NCALD,CD320,NSRP1,FAM198B,RACK1,ZMYND10,TOMM40L,MEX3B,HPCAL4,PSD2,SGIP1,SYT3,PDLIM5,MSANTD4,PHYHIPL,GALNT15,GAP43,SPIN1,GNAS,CCDC184,NUDT21,FAM107A,DDX19B,GABARAPL2,SYNPO,AGBL5,OPALIN,KHK,STMN1,NCOA7,MYBPC1,FXYD6,SNTG1,PCSK5,GPR85,OLA1,CAMKV,PKM,MTRF1L,PACSIN1,KANSL1,PTN,QDPR,RAB5B,ROGDI,TRIM68,NUDT11,TMLHE,FAM192A,AP1AR,FAM19A1,SOX6,FOXRED1,FAM214B,KANSL3,SMARCE1,LIMCH1,FAM126B,SCN3B,TSPYL2,KLHL7,TCF12,SLC35G2,MTMR14,ZNF346,SYNPO2,SSBP2,PLEKHH2,USP1,KLC2,TFIP11,RGMA,ITM2C,PHTF2,TIGD6,SSPN,SENP7" Pubmed 19058789 A common variant in DRD3 receptor is associated with autism spectrum disorder. Pubmed 5.93E-15 1.36E-09 1.01E-11 1.30E-10 45 129 "ADRA1B,NLGN4X,APAF1,CAMK2B,CCK,CHRNA4,CNR1,CSNK1E,DLX1,SLC12A6,DRD1,RASGRP1,PPP1R1B,GABRA3,GABRA5,GABRB3,GAD2,MCHR1,GRM8,HTR2A,INPP1,KCNN3,MAOB,NPY,NPTX2,NRCAM,OPRL1,CDK14,NLGN3,RELN,TMEM100,HES6,SCG5,SLC6A1,SNAP25,COBL,NR2E1,TSC1,TSC2,TUB,UBE2H,UBE3A,SLC30A4,ST7,NLRP3" Pubmed 18250082 Gene expression in cortical interneuron precursors is prescient of their mature function. Pubmed 7.29E-15 1.68E-09 1.23E-11 1.59E-10 16 18 "DPF1,SLC12A5,CACNB4,SLC32A1,ZEB2,GAD1,GRIA1,NPY,NXPH1,POU3F4,SATB1,SLC12A2,SST,TAC1,CUX2,SSBP2" Pubmed 26167880 SR protein kinases promote splicing of nonconsensus introns. Pubmed 7.45E-15 1.71E-09 1.25E-11 1.61E-10 85 361 "PNMA8B,ANK3,SFMBT2,SPTBN4,CDK13,MYOM1,AP1M1,MAP7,ZMYM4,SRSF11,CLU,TJP2,ANKRD35,CHD1L,RBM39,CTNND2,MATR3,IP6K1,YTHDC1,CEP170,DDX46,DNAH9,CELSR3,EIF4G1,ELAVL3,MFSD10,SRRM1,DENND4A,RASL12,F5,TUBA1B,ZMYND10,FGFR3,CAMSAP1,SCARA3,ANKFY1,ZCCHC17,HRASLS5,ZNF234,CYP46A1,GHR,HTATSF1,PRRC2B,DIDO1,CLASRP,C1orf94,HNMT,HNRNPK,MAP4,NF1,SDK2,EPB41L4B,VSTM2L,PSMD13,RASGRF1,RBBP6,ZFHX4,SAFB,TRA2B,PALLD,SON,MYCBP2,ERC1,ZC3H13,SRPK2,CLASP2,FCHO1,PHLDB1,GSE1,PRRC2C,MTCL1,CLASP1,FAM189A1,ARHGEF12,CRTC1,ASXL3,ZFP91,TMPO,HSPBP1,MICU3,FIP1L1,SLC17A6,EPM2A,HNRNPA3,JMJD1C" Pubmed 19874574 Genetical genomic determinants of alcohol consumption in rats and humans. Pubmed 8.22E-15 1.89E-09 1.37E-11 1.77E-10 45 130 "ADRB2,ARRB2,MPDZ,CDK5R1,CCK,CCKBR,CHRM1,CHRM4,CHRNA4,CHRNB2,CNR1,CLOCK,CRHBP,SLC32A1,CSNK1E,DBI,DRD1,GPHN,PPP1R1B,GABRA2,GABRA3,GABRA4,GABRB1,GABRB3,GABRG2,GAD1,GAD2,GLRB,GRIK1,GRIN1,GRIN2C,NR3C1,GRM1,HTR2A,MAOB,NPY,NTRK2,OPRL1,PDYN,PENK,MAPK3,SLC6A7,SLC6A11,TAC1,NTSR2" Pubmed 21368052 MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. Pubmed 8.48E-15 1.95E-09 1.40E-11 1.81E-10 27 51 "ASCL1,BMP7,CALB2,DLX1,ELAVL2,ETV1,TUBB3,FOXG1,TBR1,GAD1,GAP43,L1CAM,MEF2C,MEIS2,MSI1,NEUROD1,PAX6,POLG,POU3F2,RELN,RORB,ARX,SMARCE1,SOX5,CNTN2,SATB2,NR2E1" Pubmed 10574462 Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.16E-14 2.66E-09 1.90E-11 2.45E-10 39 102 "NDRG2,TMCC3,PLEKHH1,GRAMD1B,USP31,KIAA1211,RNF150,ESYT2,LRFN2,KIDINS220,NLGN4X,MTA3,ZNF608,INTS2,MTUS1,CCPG1,GDA,KIF26A,DLG3,ANKFY1,FAM184B,DENND2A,BRPF3,GRID1,ZDHHC8,PLXNB3,KANSL1,PPP1R9A,CCDC88A,OGDHL,BDP1,ERBIN,SULF2,SYNE1,FSTL5,PRDM10,PAK5,ADAMTSL3,VANGL2" Pubmed 16964243 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Pubmed 1.18E-14 2.71E-09 1.92E-11 2.48E-10 106 503 "ABCF1,ADAR,TAOK1,BCAR3,MRTFA,ZNF687,BEGAIN,AMPD2,APC,CDK13,NUMB,EIF4G3,BACH1,BLM,FUBP1,KALRN,MAP7,PRC1,CDK11B,ARHGEF2,LRRFIP1,TBRG4,EPS15L1,TJP2,NIPBL,ARHGEF6,AHCTF1,NCOR1,YTHDC1,ZC3H11A,SEC16A,DPYSL2,FAM13A,EIF4G1,SORBS3,EPB41L1,EPB41L2,GPHN,SRRM1,NSRP1,WAC,AGAP3,TACC2,STAU2,SEPT9,BRD8,ZNF638,PSRC1,GRB10,DIDO1,KAT7,ATXN2L,HNRNPK,IFI16,KLC1,STMN1,MAP4,AFDN,DBNL,HNRNPM,NAP1L1,NASP,NUMA1,CHAMP1,PDE3A,PDE4D,PFKP,ANLN,PKM,STRN3,PMS2,MED1,PKN2,USP47,RBBP6,PBRM1,MCMBP,CLIP1,SAFB,TRA2B,ARFGAP1,EPC1,KIF13A,PALLD,SON,FNBP1,ERC1,ZC3H13,RBM26,EPB41L3,ZC3H4,MTCL1,TAF6,EXOC7,SIRT1,TP53BP1,METTL3,TBC1D15,KLC2,SF1,WNK1,ZXDA,NAV2,FIP1L1,NELFE,LAS1L" Pubmed 15582152 A neurogenomics approach to gene expression analysis in the developing brain. Pubmed 1.41E-14 3.23E-09 2.27E-11 2.94E-10 48 147 "ADCY6,SPARCL1,MADD,NRP2,FUBP1,SCAPER,CAMK2A,CD86,ARHGEF1,NRXN2,COL4A5,RBM39,VCAN,CST3,PPP6R2,TM9SF4,NTM,TSPAN5,GORAB,NSG1,GABRG2,FAM19A2,IGF1,STMN1,NCAM1,SLCO1C1,NPR2,NRDC,PCDH9,PDE3B,ABCB1,PKD1,PKM,LRRN3,SNRK,PTPN13,SUSD4,ROGDI,ROBO2,RTN1,TAB2,PRRC2C,FAM208A,ZEB1,FSTL5,WNK1,SCG2,NETO2" Pubmed 17207965 "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." Pubmed 1.43E-14 3.29E-09 2.30E-11 2.97E-10 259 1675 "SERPINA3,C3orf14,ERMN,SNX32,TRMT9B,ANK1,LCORL,CNIH2,NT5C3B,PHYHD1,VAT1L,AQP4,TMEM263,ARRB1,CCDC74A,ASPH,CHID1,B3GALT2,SEC11C,CDK5R1,LDLRAD4,CFAP410,CA4,CA8,SYT6,VSTM2A,NFS1,KYAT1,AP4M1,CDO1,CIART,CBARP,C7orf61,RAB28,PPT2,QKI,LY86,ARMC8,LETMD1,RCHY1,IFFO1,ACBD5,CRHBP,HAPLN1,GDA,PDE4DIP,PLXNA4,CMTM5,DCAF4,ECE2,KATNAL2,SNPH,PHF19,CENPL,ACY3,IST1,TMEM170A,SCRN1,PABPC5,DBI,ELMO1,B3GAT3,CNIH3,FBXO25,GUCD1,ALKBH8,SPOCK3,NTM,DMTF1,RCAN1,DTNA,FIS1,GOLT1B,SEZ6L2,TSPAN5,EDN3,APH1A,MRO,EIF5,MRNIP,C3orf18,HSD17B14,MRPL37,TMEM74,RASL12,SIRPB1,GMPR2,CLVS1,AMZ2,SH3YL1,CACNG3,FCGR3A,ACTL6B,PRKAG2,SCARA3,EVL,DCTN2,C2orf88,WDR83,TMEM107,AK8,FAM49B,ERGIC3,ST6GALNAC3,PNMA2,TPPP3,HRASLS5,ARPP21,C15orf41,STARD10,RUNDC3A,COPS8,GNAL,GNAS,PSRC1,LILRA2,RFFL,BTN2A1,GSTM5,BVES,MAEL,RASSF8,C1orf94,DDX19B,ELOVL5,ATCAY,C5orf24,LRRC25,DIPK1A,TUBB2B,KCNA6,KCNJ5,KCNN3,KPNA5,LMO1,PACRG,CLEC18A,AQP11,KCTD6,MIA2,KITLG,POC1B,MOBP,DBNL,MSR1,TAGLN3,MYL3,PAH,PALM,ETFRF1,PCMT1,TMOD2,DUSP26,GDAP1L1,PIK3R1,FAM218A,RETREG1,KCTD15,SLC25A23,HMGCLL1,ASPDH,MTRF1L,C11orf49,ANKRD16,NXPH1,PPM1B,PPP3CC,NKAIN4,DIRAS2,CYBC1,SYTL2,PLPPR1,ELOVL2,C1orf109,ZSCAN2,PPP2R3C,BEND5,RBBP6,KHDRBS2,DUSP15,PRRT2,MRPS18A,DCUN1D2,KLHDC8A,ROM1,TMEM206,MRAP2,ACER3,RIMKLA,PTGR2,SYNDIG1,CCDC112,HOGA1,SCP2,ASIC4,ZNF821,COPZ1,NTNG1,ST6GAL1,CCDC92,ST3GAL3,NUBPL,PAAF1,RUFY2,CDK5RAP3,NAPB,ARFGAP1,COA1,ANKRD36,SNAP25,CABCOCO1,FAIM2,ZNF415,RBM34,NMNAT2,IZUMO4,ZNF302,INKA2,ELOVL4,APOM,FAM168A,NUDT10,FNDC9,SYP,SYPL1,POPDC3,RALYL,RNF175,C18orf54,ZMAT3,AKTIP,ACTR6,ERCC6L2,TMPO,C9orf85,CHST5,TTPA,RPRM,RPL7L1,SLC35A4,GORASP1,MEAF6,CLDND1,CFAP298,ZNF19,TMEM198,PROCA1,FTSJ1,PRTFDC1,DNALI1,SHD,KCNAB1,ITM2C,MVB12B,PARP11,GOPC,SMIM8,MSRB3,SOCS4" Pubmed 16710414 The DNA sequence and biological annotation of human chromosome 1. Pubmed 1.48E-14 3.39E-09 2.35E-11 3.04E-10 178 1031 "FAM43B,CSMD2,ARID1A,CDC7,ADORA3,AK2,LRRC7,BCAR3,MRTFA,ZNF687,CDC42BPA,KCNAB2,MIER1,PTCH2,BRINP2,ASTN1,ALDH4A1,ATP1A1,B3GALT2,CADM3,ADGRB2,C1QC,LURAP1,PTBP2,SYT6,SLC16A4,C1orf52,CDC42,CIART,CNN3,ANKRD35,BTF3L4,COL9A2,NSL1,CHD5,SDC3,KIAA0040,CTH,SLC45A1,PUM1,NOS1AP,CENPL,RIMS3,TOMM20,DNAJC6,CNIH3,CEP170,SMG7,SV2A,FAM78B,PHC2,EFNA3,SH3GLB1,GPR61,KCTD3,ELAVL4,EPB41,SRRM1,MRPL37,SRARP,EXTL1,F3,RPS6KC1,TOMM40L,GORAB,MAD2L2,FGR,HPCAL4,SEMA6C,SGIP1,EFCAB2,ZCCHC17,GPR153,AP4B1,ILDR2,AHCYL1,DISC1,GLUL,PSRC1,MFSD2A,MAEL,IGSF21,PADI2,ACOT7,NEGR1,IFI16,DOCK7,HES5,IL6R,IBA57,BRINP3,ZNF678,DIPK1A,INPP5B,SLC6A17,ITPKB,KCND3,KCNJ9,KCNJ10,STMN1,MARK1,LYPLAL1,MDM4,MOV10,NASP,NCF2,NFIA,NPPA,NRDC,PBX1,CDK18,PFKFB2,PRRX1,SPATA6,DRAM2,PRKAB2,PRKACB,PKN2,PRKCZ,GON4L,NKAIN1,C1orf54,BSDC1,RFX5,RGS4,RGS7,TTLL7,RNF220,CYB561D1,TMEM206,YY1AP1,RIMKLA,WLS,RXRG,DRAXIN,SCNN1D,STUM,ASAP3,NTNG1,CLSTN1,TRIM67,SCMH1,RCOR3,RBM34,KIF21B,NMNAT2,EMC1,NFASC,TROVE2,POGZ,CAMTA1,TAL1,CNTN2,TBX15,SZT2,AZIN2,ATP13A2,CRB1,ITGB3BP,GPR161,TGFBR3,TNFRSF1B,TNR,NPL,TPM3,CA14,MEAF6,FMN2,INTS3,PRDM2,DNALI1,CSDE1,EVI5,SNX27,GJC2,CAMK1G,NLRP3,VANGL2" Pubmed 11471062 High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Pubmed 1.84E-14 4.22E-09 2.91E-11 3.76E-10 28 56 "SYN3,ACLY,SLC12A5,NRP2,CHN1,CST3,SIRPA,MYEF2,MED24,RBM12,EZH1,RASL10A,GAD1,INPP5K,GFAP,GGT7,MCHR1,KCNJ4,MAPT,PCSK2,PDYN,MED1,PTPRN,ZFP2,SLA,SNAP25,PLCB1,ZNF142" Pubmed 21862448 Gene expression analysis of the embryonic subplate. Pubmed 1.94E-14 4.46E-09 3.06E-11 3.95E-10 22 35 "CSMD3,CDH10,CDH18,ZNF521,PLXNA4,SV2B,RCAN2,GABRA5,GAD1,LRRTM3,KIT,MYO9A,NEUROD1,RELN,RASGRF1,RORB,SEMA6D,SLC8A2,SLC8A1,SLIT1,UNC5D,KCNT2" Pubmed 19029045 A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster. Pubmed 2.48E-14 5.69E-09 3.87E-11 5.00E-10 26 49 "PCDHGB4,BSN,CALB1,LHX2,SLC32A1,DLG4,GPHN,GFAP,NKX2-2,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SLC17A7,TMEM163,SLC17A6" Pubmed 23602568 The protein interaction landscape of the human CMGC kinase group. Pubmed 3.04E-14 6.97E-09 4.71E-11 6.09E-10 132 694 "CLK4,AXIN2,ESYT2,EP400,APC,CDK10,CASK,ARNTL,CDK13,DYNLL1,ATP1A1,AZGP1,BACH1,CDK5R1,FOXK1,CAMK2D,TRIM41,CCNH,CCNT1,EVI5L,FOXN3,CLU,TJP2,HOMER3,RBM39,SIPA1L1,RIMS4,YTHDC1,MED24,DDX46,MED12,PDCD6IP,DUSP9,DYRK1A,EDIL3,EEF1A2,HIPK3,FRY,SUGP2,RASA4,SRPK3,EPB41L1,SRRM1,ERBB2,ERCC2,CDKL3,NSRP1,CACNG2,KAT8,FGF12,FGFR1,BAIAP2,FHL1,SEC23B,FLT1,NOP56,NSG1,NEURL4,HBS1L,AHCYL1,ZMYND11,KIAA1841,RNPS1,MSL3,STON1,NUDT21,DIDO1,CLASRP,FAM222A,HMGB1,KCNN2,ARHGAP12,SRSF12,AFF1,MTR,HNRNPM,NOVA1,CDK18,PDGFRA,PDPK1,PFKP,CDK14,PKM,MED1,PPP5C,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MASP1,LAMA1,PTK2,CEP97,RBBP6,HKR1,RDX,ZMAT4,RIT2,RPS6KA2,ATAT1,NCBP3,FAM192A,MAPK12,TRA2B,SHANK2,RBM34,SON,ERC1,ARHGAP26,SPTAN1,CDK19,C11orf87,SRPK2,NXT2,STAU1,OBSL1,AHCYL2,TEK,SIRT1,CBX5,FAM124A,TPD52,CDK20,TRPS1,DHX33,PPP1R3F,KCNAB1,FIP1L1,NELFE,ZNF30" Pubmed 17124501 Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. Pubmed 4.06E-14 9.33E-09 6.26E-11 8.09E-10 18 24 "PPFIA1,CASK,RAB3C,ERC2,RIMS2,SV2B,DLG4,CPLX2,RAB3A,RPH3A,RIMS1,SNAP25,ERC1,STX1A,STXBP1,SYP,SYT1,RIMBP2" Pubmed 10997877 Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 4.63E-14 1.06E-08 7.09E-11 9.17E-10 38 101 "EPB41L5,GPAM,ALS2,CACHD1,VAT1L,LRRC4C,TNRC6C,USP37,SHTN1,CPNE5,MIER1,SLC7A14,KIAA1614,SFMBT2,SEMA4G,PRX,PPP4R4,IGDCC4,SPTBN4,ZFYVE28,PLXNA4,MED12L,FLYWCH1,NBEA,MOV10,PCDH18,SYTL2,GON4L,CCDC40,ARHGEF10L,ZNF532,RAVER2,ROBO2,KIF16B,MAGI3,CDK5RAP2,ANKRD36,WNK3" Pubmed 28065597 A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Pubmed 5.27E-14 1.21E-08 8.02E-11 1.04E-09 92 419 "RBM10,USP31,HECW2,ALK,CCDC146,API5,MIER1,CDK13,ATP1A1,ALDH7A1,MTMR9,KIF1A,MTMR3,MTMR2,CANX,CDC25B,ZMYM4,SRSF11,RBM39,AATK,CSF1R,CENPL,CEP170,SEC16A,DUSP9,AASDH,SNX29,EGFR,EIF4G2,ING4,EPB41L2,EPHA5,SRRM1,ERBB2,ERBB4,FOXO3,GABRA3,SYT17,SRRM4,GLUL,HTATSF1,GOLGB1,GRID1,GRIK4,PTPRT,HMGB1,HNRNPK,KIT,MAP4,PPM1L,XRRA1,MYO9A,NF1,PDE1C,DUSP26,SSH1,ZFYVE21,TRHDE,PPM1B,PPP3CA,PPP3CB,RASGEF1B,MTMR10,PTPRB,PTPRH,PID1,DUSP15,RET,RPS20,SBF1,LRRTM4,TRA2B,DOCK10,SLITRK3,SHANK2,FAM126B,UNC80,DOP1A,TNIK,DIP2A,ZC3H4,SUPT5H,AGTPBP1,PCDHGA3,TEK,DNAH7,MTMR14,TIE1,RUNDC3B,ZBTB14,EML6,LRP8" Pubmed 20610746 NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. Pubmed 5.71E-14 1.31E-08 8.63E-11 1.12E-09 20 30 "ASCL1,CALB1,CALB2,LHX2,OLIG1,OLIG2,TBR1,GFAP,GRIK4,HES5,NFIA,PAX6,PROX1,RELN,SOX8,S100B,SLC1A3,SOX3,SOX10,HEY1" Pubmed 15601927 CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure. Pubmed 7.19E-14 1.65E-08 1.08E-10 1.40E-09 13 13 "CNTNAP1,CNTN1,NKX6-2,KCNA2,STMN1,MAG,MBP,CLDN11,PLP1,SCN8A,NFASC,EPB41L3,CNTN2" Pubmed 27107014 An inter-species protein-protein interaction network across vast evolutionary distance. Pubmed 8.25E-14 1.90E-08 1.23E-10 1.59E-09 101 483 "SERPINA3,C1QTNF1,SPOP,BBOX1,GPRASP2,OGT,RGS20,CAMK2B,CAMK2D,TRIM41,CAPN3,CBS,CDC27,ZBED1,EVI5L,CFL2,COPB2,RCBTB2,CNOT8,QKI,HOMER3,FHL5,TRIM69,SEC24C,PDE4DIP,CMTM5,TBC1D5,ACY3,JAKMIP2,KLHL3,BLOC1S6,USH1C,PHC2,OPTN,SH3GLB1,ABI2,BSCL2,HSD17B14,EFS,RTN3,KATNAL1,WAC,AMOTL2,SEC23B,CAP2,ZCCHC17,KHDRBS3,SDCBP2,GAD1,TUBGCP4,GFAP,LNX1,NUDT21,C1orf94,PACSIN2,MAT2A,MDFI,MX1,NFYA,NUCB1,ZNF426,C11orf49,NECAB2,POLR2F,C19orf57,MAPK7,ANKHD1,RBBP8,KHDRBS2,ZMAT4,RPE,MCMBP,KCNIP3,S100B,PUF60,CCDC92,FAM214B,GKAP1,ABTB1,RCOR3,DBNDD2,CAMTA2,EXOC7,TRIM2,RALYL,ARHGAP9,FAM124A,RBFOX2,SSBP2,HSPBP1,UBC,EIF4ENIF1,SH3GLB2,PRTFDC1,NAV2,FIP1L1,PLSCR4,GOPC,DOCK8,RTN4,PAK5" Pubmed 22863883 A high-throughput approach for measuring temporal changes in the interactome. Pubmed 8.76E-14 2.01E-08 1.30E-10 1.68E-09 229 1456 "ABCF1,ACADM,ACLY,ACTN1,MTA3,AP1B1,ALAD,AMPD2,BIN1,OGT,PPFIA1,API5,SHTN1,CCAR2,DYNLL1,ALDH7A1,FUBP1,NAE1,MTMR2,AP1M1,FOXK1,CAST,CARS,SPAG9,MAP7,CBS,ARHGEF1,LRBA,SEPT7,CDC42,LRRFIP1,COPB2,EPS15L1,PLAA,CLU,TJP2,HECTD1,BTF3L4,AKAP12,CRMP1,GDA,CS,SEC24C,ARHGEF10,APPL1,CTH,GAPVD1,DCAF8,IST1,SCRN1,COPS7A,SEC16A,DNM1,DPYSL2,PDCD6IP,GNE,TOM1,FARSB,DNM1L,EEF1A2,EEF1D,OPTN,RBM12,SH3GLB1,ABI2,EIF4G1,EIF5,COPS4,DCTN4,ENO2,EPB41L1,EPB41L2,GPHN,RRAGB,GMPR2,TUBB3,TUBB4A,RACK1,PRMT5,SEC23B,CAP2,SYNCRIP,FLNC,ANKFY1,DCTN2,SMC2,UFM1,PDLIM5,STAMBP,TRIM16,ATP6V1H,PNMA2,OGA,HBS1L,AHCYL1,NCKAP1,GART,ARFIP1,WASHC2A,USP19,COPS8,GLS,GLUL,HTATSF1,FERMT2,PRUNE2,NUDT21,TUBA1C,NR3C1,ATE1,PACSIN2,DDX19B,ACOT7,HNRNPK,AGFG1,HSPA1L,HSP90AA1,KLC1,IPO5,KTN1,LAMP2,NCOA7,MAP2,MAP4,MAT2A,GIT1,DBNL,MTR,NACA,HNRNPM,NAP1L1,NASP,NRDC,NUCB1,NUCB2,PDE3A,PDE4D,OLA1,PFKP,SERPINE2,PKM,PLEC,FTO,EPN1,STRN3,PSAT1,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PPP5C,PRKACB,PRKAR1B,PRPSAP2,PSMA6,QRICH1,PSMD13,SPDL1,PEX5,RIPOR1,USP47,ATG16L1,RAP1GDS1,OXR1,RDX,UBR7,RPRD1A,RNH1,MYH14,ELP2,RPL15,MCMBP,RPL38,RPS20,CLIP1,SARS,COPZ1,HSPA4L,PUF60,KIF21A,SHMT2,PAAF1,PPP4R3A,RAB3GAP1,ARFGAP1,INTS9,LIMCH1,SNCA,KIF13A,PEG10,SPTAN1,KIF1B,TROVE2,SMOC1,NCDN,GANAB,NSFL1C,JMJD6,SUPT5H,ANKRD28,MMS19,DNMBP,TCEA1,WASHC4,FRYL,SIRT1,TPD52,TPD52L2,TPM1,TPM2,TPM3,TPM4,TSN,HSPBP1,TUBB2A,UBE2H,UBE3A,TBC1D15,KLC2,XPO1,SF1,SH3GLB2,SMARCAD1,WNK1,CSDE1,PARP6,TUBA1A,CIAPIN1,GOPC" Pubmed 19615732 Defining the human deubiquitinating enzyme interaction landscape. Pubmed 9.11E-14 2.09E-08 1.34E-10 1.73E-09 172 1005 "ACADM,KLHL13,SRPX,GPRASP2,OGT,USP28,APBA2,APC,USP37,CASK,MARK4,DYNLL1,EIF4G3,AZGP1,ADGRB1,BARD1,MPDZ,NAE1,BTRC,FOXK1,CALM1,CAMK2D,CAMK2G,USP6,USP2,ARHGEF2,CDC25B,LONRF2,CDC27,ZMYM4,CLTA,FBXO7,TJP2,QKI,HECTD1,MAP4K4,AKAP7,ARMC8,COL11A2,TCEAL2,PREPL,CS,ARHGEF10,SIPA1L1,UBXN2A,CTNND1,PPP6R2,DCAF4,GPRASP1,FGFR1OP2,TCAF1,DBT,SPATA2,COPS7A,G3BP2,WDR20,USP3,DTNA,E2F5,FEM1B,OPTN,KCTD3,EIF4G1,EIF4G2,COPS4,PAN3,USPL1,GPHN,CEP85L,SCML2,FECH,POLR1B,RGPD5,FLNC,ANKFY1,USP16,STAMBP,USP21,CELF1,OGA,NEURL4,AHCYL1,USP19,TXNL4A,COPS8,GLDC,CBX1,GNAL,GPT2,PRRC2B,ATE1,KIF3A,DDX19B,ATXN2L,IDH3A,DOCK7,KLHL23,IPO5,KTN1,SYTL4,MARK1,MARK3,KCTD6,MOG,BLOC1S2,MYO6,NDUFA5,NRDC,OGDH,PDCD2,PFKP,PGAM2,PIK3C2A,PLEC,STRN3,PPP5C,PKN2,PSMA6,TMEM104,PSMD13,USP47,RAD17,RDX,ZYG11B,KIF7,SEC61A2,RNF220,RNH1,MCMBP,SAFB,SUPT20H,PPP1R9A,SHMT2,MAGI3,AMBRA1,FBXO11,CNKSR2,PAAF1,USP33,WDTC1,KDM3A,MYCBP2,CLASP2,NSFL1C,ANKRD28,MMS19,MTCL1,TAF9,FBXW11,KIAA0930,USP22,AHCYL2,DICER1,SIRT1,TJP1,RIMBP2,TP53BP1,AMOT,UCHL1,USP1,CCDC14,WRN,ZNF24,USP32P2,POLR3H,FTSJ1,DHX33,TUBA1A,SNX27,NELFE,PARP11,NUP214" Pubmed 18725516 Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Pubmed 9.18E-14 2.11E-08 1.34E-10 1.74E-09 30 67 "TTYH1,NDRG2,CARMIL3,SDC3,AIF1L,EDNRB,ELAVL2,ELAVL4,NRN1,CLVS1,OLFM1,FGFR3,NSG2,DLL3,INSM1,CCDC80,MYT1,NEUROD1,PPP1R1A,LRRN3,RASGEF1B,HES6,ARX,SYBU,SLC1A3,SOX11,SSTR2,MGAT5B,LRP8,SLC17A6" Pubmed 15347688 Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha. Pubmed 1.27E-13 2.92E-08 1.85E-10 2.39E-09 21 34 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 19723505 SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch. Pubmed 1.46E-13 3.36E-08 2.11E-10 2.73E-09 20 31 "ASCL1,OLIG2,FGFR3,DLL3,GFAP,SOX21,HES5,MBP,NFIA,NKX2-2,PAX6,PDGFRA,SOX8,S100B,SOX6,SLC1A3,SOX1,SOX2,SOX3,SOX10" Pubmed 15772651 The DNA sequence of the human X chromosome. Pubmed 1.49E-13 3.43E-08 2.14E-10 2.77E-09 89 406 "TKTL1,KLHL13,PCDH19,SRPX,GPRASP2,LRCH2,MAGEE2,UPRT,SHROOM2,BTK,SLC25A14,RGN,AIFM1,CHM,RAB33A,ARHGEF6,MAGED1,TCEAL2,GPRASP1,PABPC5,ARMCX4,ARMCX2,CHRDL1,RAB39B,DMD,DUSP9,TENM1,TMEM35A,RAB9B,RRAGB,ARMCX1,TMEM164,FHL1,AFF2,STAG2,PCDH11X,HTATSF1,MAP7D2,LPAR4,ARHGAP36,ZDHHC15,USP51,TCEAL6,RAB41,L1CAM,LAMP2,SYTL4,MAOB,CHIC1,RTL5,NEXMIF,TCEAL5,BEX5,NAP1L3,ZC3H12B,OCRL,OPHN1,PAK3,PLP1,POU3F4,SMIM10L2B,GDPD2,TMEM255A,RADX,MORC4,NUDT11,TMLHE,SPIN3,CNKSR2,DMRTC1,SOX3,BEX1,IQSEC2,ZC4H2,NXT2,ARHGEF9,NUDT10,SYN1,PJA1,KLHL4,BEX4,TRO,ZIC3,ZNF711,TCEAL7,FTSJ1,ZXDA,WNK3,LAS1L" Pubmed 19328558 Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Pubmed 1.57E-13 3.62E-08 2.25E-10 2.90E-09 26 52 "SORCS2,ARNTL,CAMK2A,CLOCK,DPYSL2,PDLIM5,GABRA5,GAD1,DISC1,GNAL,GRIK4,GRIN1,GRM3,GRM7,CIT,HTR2A,HTR5A,MTR,NCAM1,NOS1,P2RX7,RFX4,KIF13A,SST,CUX2,MPPE1" Pubmed 29055695 Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Pubmed 1.68E-13 3.86E-08 2.38E-10 3.08E-09 27 56 "OGT,PTBP2,SRSF11,ZNF521,RBM39,MATR3,ZEB2,MBNL2,SYNCRIP,HNRNPK,HES5,MEIS2,NOVA1,PAX6,PBX1,OLA1,STRN3,RC3H2,MED1,SETD5,SFPQ,TRA2B,NPAS3,TCF12,RBFOX2,XPO1,CSDE1" Pubmed 22360420 "Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration." Pubmed 3.46E-13 7.94E-08 4.87E-10 6.29E-09 36 97 "SYN3,AP2A1,AP2A2,AP1B1,AMPH,CNTNAP1,AQP4,CADM3,CALB2,CAMK2A,CBR1,VCAN,SCRN1,DNM2,ENO2,SIRPB1,HSPA12B,ATP6V1H,GFAP,GLS,NEGR1,HSP90AA1,PSAT1,PPP3CA,PPP3CC,PRPH,PRRT2,STX1B,MYH15,SPTB,NCDN,STX1A,STXBP1,SYT1,TUBB2A,TUBB1" Pubmed 12588844 BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Pubmed 3.67E-13 8.43E-08 5.14E-10 6.64E-09 15 18 "SLC12A5,CALB1,CALB2,GABRA1,GABRA2,GAD1,GAD2,GRIA1,GRIA2,GRIN1,RELN,STX1B,STX1A,SYN1,SYP" Pubmed 16330018 Brg1 is required for murine neural stem cell maintenance and gliogenesis. Pubmed 7.29E-13 1.68E-07 1.02E-09 1.31E-08 16 21 "CALB2,ELAVL3,ELAVL4,OLIG2,TUBB3,GFAP,MBP,MSI1,NKX2-2,PAX6,PDGFRA,PLP1,RELN,S100B,SMARCA4,SOX1" Pubmed 28489004 Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Pubmed 7.66E-13 1.76E-07 1.06E-09 1.37E-08 28 63 "TTYH1,ATP1A2,CA8,CALB1,CLU,CST3,DBI,FABP7,FGFR1,GABRB1,GBX2,ALDH1L1,GFAP,GPM6B,FAM107A,TUBB2B,SHC3,PAX6,NKAIN4,MAPK3,PTN,PTPRZ1,SLC1A2,SLC1A3,SOX2,ACSBG1,TIMP4,TUBB2A" Pubmed 27565344 Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Pubmed 8.17E-13 1.88E-07 1.12E-09 1.45E-08 20 33 "ADD1,SGCE,DCTN1,ABI1,EPB41L1,GPHN,EVL,DCLK2,EML4,KIF2A,PAX6,CLIP1,KIF21A,ELMO2,SOX2,CLASP2,EPB41L3,SYNE2,CLASP1,CLIP2" Pubmed 24457600 The central role of EED in the orchestration of polycomb group complexes. Pubmed 8.21E-13 1.89E-07 1.12E-09 1.45E-08 257 1719 "ABCF1,ACLY,AS3MT,ACTN1,ARID1A,ADAR,ADD3,MTA3,AP2A1,AP2A2,ZNF687,OGT,ANK3,EP400,PKP4,ANXA7,EPB41L5,GPAM,API5,APP,ARHGDIA,CDK13,NUMB,CCAR2,DYNLL1,ATP1A1,ATP2A2,ATP2B1,ATP6V0A1,SYNJ1,FUBP1,AP1M1,CACNB4,CALM1,TRIM41,CANX,CBR1,FMNL3,AIFM1,LRRFIP1,COPB2,EPS15L1,CPNE6,PLAA,MYL6B,CLTC,TJP2,NIPBL,CNN3,RCHY1,AHCTF1,SEC31B,CDC42BPB,RBM39,SIPA1L1,PDE4DIP,CTNND1,PUM1,MYADM,GAPVD1,PHF19,MATR3,INTS1,DAPK1,TOMM20,DBN1,DBT,YTHDC1,DCTN1,MYEF2,TIAM2,HP1BP3,ZC3H11A,G3BP2,SEC16A,MED12,DNM2,ACOT8,PDCD6IP,TOM1,FARSB,DNM1L,PHC2,FCF1,EEF1D,YAF2,SUGP2,MBNL2,EIF4G1,ELAVL2,MFSD10,EZH1,ACSL4,TUBA1B,PTK2B,SCML2,RACK1,SYNCRIP,RGPD5,ANKFY1,NOP56,SMC2,SPECC1,PDLIM5,USP21,ATP6V1H,ATP2C1,KHDRBS3,CELF1,STAU2,ZNF512,STAG2,CHL1,NCKAP1,SEPT9,GART,TCERG1,COPS8,RNPS1,GLDC,GLYR1,ZNF638,CBX1,KDM2B,FERMT2,TDRKH,NUDT21,TUBA1C,DIDO1,CIT,GSN,KAT7,ADAMTS6,ATXN2L,HNRNPK,HSP90AA1,ZNF385B,SLC35G1,KCNMA1,KLC1,IPO5,KTN1,LIMS1,PAXBP1,AFDN,MOV10,SESN3,MTTP,MDGA1,MYL3,MYO6,HNRNPM,NAP1L1,NME4,NUMA1,FAM98B,OLA1,PIK3C2A,ANLN,XRN1,PKM,PLEC,FTO,EPN1,PSAT1,EXOSC10,VPS13C,PSMA6,LAMA1,RAB3IL1,RAB5B,RAP1GAP,ENOX1,RDX,DPF2,PBRM1,MYH14,RPL15,ZC3H14,RPL38,RPS20,CLIP1,RYR3,NCBP3,SAFB,ATXN2,CASC3,SFPQ,TRA2B,COPZ1,PUF60,MYO18A,FBXO11,SEC31A,NUBPL,EPN2,DHX30,RAB3GAP1,SIRT2,SCMH1,CPEB4,SMARCA4,SMARCC2,CDK5RAP2,SMARCE1,LIMCH1,SNRPN,RBM34,SON,CAND2,MYCBP2,ZC3H13,SPTAN1,SRPK2,POGZ,MPRIP,STAU1,ZC3H4,SUPT5H,DNAJC9,MMS19,MLST8,FAM208A,WASHC4,SZT2,SYNE1,NSD1,PUM2,TJP1,ZFP91,TMPO,TP53BP1,RBFOX2,TPM3,ZNF346,TRIO,TUBB2A,RPL7L1,UBTF,VGF,TBC1D15,NSD2,KLC2,RICTOR,XPO1,SF1,ZSCAN26,TFIP11,SMARCAD1,DHX33,INTS3,VPS35L,FIP1L1,HNRNPA3,NUP214,FXR1,LAS1L" Pubmed 26928066 Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Pubmed 9.82E-13 2.26E-07 1.34E-09 1.73E-08 19 30 "ERMN,APC,MYRF,MAP7,OLIG1,OLIG2,GFAP,GLUL,TPPP,GSN,HES5,MAG,NFYA,PDGFRA,ENPP2,PLP1,SMARCA4,SOX10,TCF7L2" Pubmed 17500595 Huntingtin interacting proteins are genetic modifiers of neurodegeneration. Pubmed 1.04E-12 2.38E-07 1.40E-09 1.81E-08 50 174 "ASPH,CA4,CACNA2D1,SEPT7,TPP1,CLTC,CNTN1,NCOR1,FEZ1,ARHGAP24,SIRPA,SRGAP3,NTM,DNM1,DPYSL2,EEF1D,OPTN,EPB41,EPB41L1,WAC,RACK1,DCTN2,SORBS1,NPTN,GFAP,TCERG1,GNAO1,GPM6A,NEGR1,LSAMP,MOG,OPCML,PIK3R1,PKM,JAKMIP1,PLP1,PACSIN1,DIRAS2,STX1B,SLC1A2,SLC6A1,SNAP25,SPTAN1,STX1A,STXBP1,SYN1,SYP,SYT1,TACC1,DNALI1" Pubmed 18554416 Identification of transcripts with enriched expression in the developing and adult pancreas. Pubmed 1.26E-12 2.89E-07 1.69E-09 2.18E-08 111 575 "VWA5B2,ACLY,ACTN2,SPARCL1,ALCAM,LTBP4,SYT13,APLP1,SLC7A14,ARHGDIG,CADPS,ATP2A2,MYOM1,RGS11,BTK,HAP1,SYT6,CCK,CHGA,CHGB,CLU,COL9A2,MAGED1,ZNF385A,AKAP12,ST18,DCC,DNAJC6,DCT,USH1C,COQ7,VPS26C,SCARA3,VTI1B,EFCAB2,UFM1,ST6GALNAC3,SARAF,SDCBP2,MYOZ2,GCK,TCERG1,PCSK1N,LOXL3,FERMT2,GPD2,CCDC184,GRIK5,GSN,CELF3,HBA1,HSP90AA1,IGFBP1,ITIH2,KCNJ11,KIFC3,SYTL4,PACRG,MEST,MOV10,SCG3,MYL3,MYT1,NACA,SFR1,NEUROD1,NKX2-2,NPPA,PAX6,PCSK1,PCSK2,PDE1C,PGAM2,GDAP1L1,PRRX1,POU3F4,PPP1R1A,RAP1GAP,DPF2,ZDHHC4,MRPS18A,LGI2,TMEM206,HES6,PPP1R9A,ARX,FERMT1,SPHKAP,SLIT1,CDK5RAP2,SON,SPP1,BEX1,RAP1GAP2,APOM,FGD4,ABCC8,ARC,TCF7L2,TF,DICER1,TMOD1,BEX4,TTC3,RPL7L1,DNAJC12,PITPNB,MTCH1,ZNF24,CA10,SCG2" Pubmed 26795843 LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Pubmed 1.32E-12 3.04E-07 1.77E-09 2.28E-08 21 37 "SYN3,SYT13,ASCL1,CALB2,LHX2,DLX1,OLIG1,EMX2,OLIG2,TUBB3,TBR1,STMN2,MAP2,MAPT,RCOR2,NKX2-2,PTCH1,FEZF2,SOX2,SST,SATB2" Pubmed 22745667 Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. Pubmed 1.43E-12 3.29E-07 1.90E-09 2.46E-08 26 56 "SNX30,AMPH,BTK,ARHGEF4,RUSC2,DLG2,DLG3,DLG4,DOCK2,ABI2,SH3YL1,FGR,SORBS1,MPP6,FYN,MIA2,MYO7A,PIK3R1,PACSIN1,SH3KBP1,ITSN1,ARHGEF9,DNMBP,TJP1,VAV1,SPATA13" Pubmed 11347906 Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.45E-12 3.32E-07 1.91E-09 2.47E-08 37 106 "TMEM132B,EP400,CDK13,MARK4,CAPRIN2,DCAF5,WAC,SEMA6C,ADGRA1,MSANTD4,HHIPL1,DOT1L,BRSK1,ABLIM2,ZNF512,PHYHIPL,NEURL4,ZMAT1,MEGF11,MEGF10,FAM120B,JPH4,SRRM4,ACSS1,KIAA1841,KIRREL3,NTNG2,TTBK1,ATCAY,MAP6,CHAMP1,HYDIN,RADIL,ELMO2,UNC80,CCDC136,SH3GLB2" Pubmed 17916349 A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Pubmed 1.59E-12 3.64E-07 2.08E-09 2.69E-08 15 19 "ACHE,AXIN2,NRP2,CDH2,TUBB3,TBR1,GRIK4,HES5,MEIS2,PAX6,POU3F2,PROX1,SLC1A3,SOX2,TJP1" Pubmed 17620599 Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Pubmed 1.83E-12 4.21E-07 2.39E-09 3.09E-08 73 317 "RBM10,AP2A1,AP2A2,APLP1,DGKZ,ARRB1,ARRB2,CDK13,PTCH2,BSN,CALM1,CAMK2D,INA,CLTA,CLTB,CLTC,CNGA3,ARHGEF6,SDC3,CTNND1,ARHGAP32,KIF26A,DGKG,DBN1,G3BP2,DMD,DNM1,EEF1A2,KCTD3,TUBB3,TUBB4A,PRMT5,POLR1B,NOP56,TUBA8,SPIN1,HTATSF1,TUBA1C,GSN,KIF3A,BACH2,HNRNPK,HSPA1L,HSP90AA1,STXBP5,KTN1,LRP1B,AFDN,HNRNPM,NAP1L1,PDE4D,PFKFB3,PIK3C2A,PKM,PPM1B,RGS3,RPL15,SPIN3,SFPQ,SPTAN1,SRPK2,EPB41L3,MPRIP,ARHGEF12,TMPO,TPM4,TUBB2A,UBC,TUBA1A,KCNAB1,PAK5,HNRNPA3,AP3B2" Pubmed 15142957 Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Pubmed 1.97E-12 4.53E-07 2.56E-09 3.30E-08 28 65 "OSBPL1A,SEMA7A,CACNA2D1,CDH8,CRLF1,NGEF,CRYM,RASGRP2,ATP8A1,NEGR1,SOWAHA,LSAMP,MEF2C,MMP17,MYH7,FXYD7,NPY,PAX6,PENK,RXRG,SLC8A1,LIMCH1,SOX5,SST,TST,VSNL1,SCG2,NAV2" Pubmed 25231870 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Pubmed 2.06E-12 4.73E-07 2.66E-09 3.43E-08 45 149 "ASPHD1,ADARB2,CCDC85A,BEND6,ARNTL,DST,EVI5L,DLGAP1,DNAJC6,EIF4G1,GHR,BRD8,GPR45,KLF12,NEGR1,OLFM3,NCOA7,LRP1B,NTRK2,IGSF11,PCSK1,PCSK2,FTO,MAGEL2,WDR25,BDNF-AS,PTPRD,PTPRN2,PEX2,LGR4,RXRG,RMI1,GALNT10,TRA2B,KDM4C,WSCD1,SATB2,TCF7,CRTC1,CSMD1,STXBP4,CADM1,MKRN3,SMARCAD1,CA10" Pubmed 22365545 A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Pubmed 2.18E-12 5.01E-07 2.80E-09 3.62E-08 23 45 "AXIN2,BMP7,CALB2,SLIT2,EFNB3,EPHB1,FABP7,TBR1,GFAP,L1CAM,SMAD1,SMAD9,NBL1,NFIA,PAX6,POU3F2,FEZF2,DRAXIN,SLIT1,CNTN2,SATB2,CUX2,ZIC1" Pubmed 25838543 Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Pubmed 2.70E-12 6.21E-07 3.45E-09 4.46E-08 18 28 "AP2A1,PPFIA2,SYNJ1,SLIT2,CLTA,SHANK1,DCTN2,NBEA,TBR1,RAPGEF6,SRRM4,ZFYVE27,PAX6,VPS13C,ITSN1,SATB2,ZMYND8,VAV2" Pubmed 10819331 Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 2.76E-12 6.34E-07 3.50E-09 4.52E-08 36 103 "OSBPL8,PDZD4,BEGAIN,TRMT9B,PITPNM2,LRFN1,ZFAT,DPP10,LRCH2,EP400,CCDC146,MYH7B,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,SCAPER,KMT2C,WHRN,GAPVD1,CERCAM,TNRC6A,MARK1,CNTN3,NLGN3,SEMA5B,SDK2,ERI2,SEMA6D,SYBU,NLGN1,URGCP,RUFY2,FAM214B,BTBD7,MBD5,KIF1B" Pubmed 19165527 Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Pubmed 3.05E-12 7.01E-07 3.85E-09 4.98E-08 32 84 "SERPINA3,ERMN,PKP4,CADM3,FUBP1,BSN,CRYM,CTNND2,SIRPA,DNAJC6,HP1BP3,EPB41L1,SIRPB1,SORBS1,TPPP3,HNRNPK,ATCAY,TUBB2B,L1CAM,MAP2,MAP6,MOG,OPA1,PLEC,SEPT4,PRKCG,RLBP1,KIF21A,SH3GL2,EPB41L3,NSFL1C,RTN4" Pubmed 20861386 RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks. Pubmed 3.18E-12 7.29E-07 3.96E-09 5.12E-08 14 17 "ATP1A1,ATP1A2,ATP1A3,G3BP2,DLG4,GPHN,GABRA1,GAD2,GRIA1,GRIN1,FXYD7,FXYD6,FXYD1,SYN1" Pubmed 16606357 Expression and distribution of JNK/SAPK-associated scaffold protein JSAP1 in developing and adult mouse brain. Pubmed 3.18E-12 7.29E-07 3.96E-09 5.12E-08 14 17 "CALB1,SLC32A1,DLG4,FABP7,GAD1,GAP43,MAP2,MAPK8,MAPK9,MAPK10,MAPK8IP3,SYP,SLC17A7,SLC17A6" Pubmed 25936505 Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Pubmed 3.82E-12 8.78E-07 4.72E-09 6.10E-08 20 35 "ASCL1,NUMB,CDH2,OLIG2,FABP7,FGFR3,RBPJ,HES5,NFIA,NKX2-2,NOS1,PAX6,PDGFRA,PRKCZ,PTCH1,DBX2,SLIT1,SOX2,SOX10,PARD3" Pubmed 25798587 Ion channel expression in the developing enteric nervous system. Pubmed 3.82E-12 8.78E-07 4.72E-09 6.10E-08 20 35 "ANK3,CACNA1A,CACNA1B,CACNB4,CLCN3,CLCN4,CACNG2,TUBB3,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCND2,KCND3,KCNN1,KCNN3,KCNQ2,KCNQ3" Pubmed 26871637 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Pubmed 4.30E-12 9.87E-07 5.28E-09 6.82E-08 115 615 "ACADM,RBM10,ACTN1,ACTN2,NME5,GPRASP2,APBB2,ALS2,APOC2,ARHGDIA,ARRB1,ATP1A2,ATP2A2,BCS1L,ST3GAL5,SGCE,BTRC,CAPN3,SCARB1,LGI1,ADGRG1,HOMER3,FHL5,SUMF2,MAGED1,SDC3,CYBB,ACY3,ZBTB24,KIAA0753,DMD,CD99L2,E2F6,USH1C,ATL1,OPTN,RBM12,SORBS3,IRAK4,COPS4,BSCL2,DCTN4,RABEPK,SRRM1,ANKMY1,EFEMP1,FCGR3A,FGFR1,AMOTL2,FOXM1,KHDRBS3,PNMA2,GABRA2,GAD1,AHCYL1,SEPT9,MYOZ2,ALDH1L1,GFAP,GNAS,GPD2,ZNF496,C1orf94,HNRNPK,AGFG1,ATCAY,INPP1,ZFYVE27,MDFI,MDM4,MOBP,MXI1,NCF2,NEUROD1,NLGN3,SERPINI1,PLP1,PPP3CA,MAPK7,SPDL1,PEX5,ZCWPW1,ENOX1,BEND5,KHDRBS2,RGR,ALG9,MCMBP,ST6GALNAC6,S100B,ASAP3,SHMT2,PEX26,SP4,ARHGAP26,SPART,POGZ,ZC4H2,TRIM2,TNS2,TPM1,CDK20,TPM3,SMUG1,GORASP1,BCL2L13,BEST1,TRIM9,NDRG4,MKRN3,ZBTB16,FTSJ1,TFIP11,PRTFDC1,DOCK8" Pubmed 15033168 Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. Pubmed 4.44E-12 1.02E-06 5.43E-09 7.01E-08 32 85 "ABR,CSMD2,PHF12,ATP2B2,CADM3,FUBP1,B4GALT6,TAOK2,CLCN4,CLTB,NIPBL,SIPA1L1,SHANK1,PHC2,EML1,ERBB4,DLL3,CPLX1,RUNDC3A,PRRC2B,PTPRT,IGFBPL1,MYO5A,NCAM1,NFIX,CAMKV,ROBO1,ASRGL1,FAIM2,SYT1,DICER1,ICAM5" Pubmed 26071364 The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Pubmed 5.16E-12 1.19E-06 6.27E-09 8.10E-08 19 32 "AXIN2,ASCL1,BMP7,CALB1,CALB2,SLIT2,TUBB3,TBR1,GAD1,GFAP,L1CAM,MAP2,MAPT,NFIA,NFIX,PAX6,RFX3,SATB2,RPGRIP1L" Pubmed 22884324 Functional significance of isoform diversification in the protocadherin gamma gene cluster. Pubmed 5.28E-12 1.21E-06 6.39E-09 8.25E-08 21 39 "PCDHGB4,BSN,CALB1,SLC32A1,GFAP,PAX6,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SLC17A7" Pubmed 21307259 LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. Pubmed 5.59E-12 1.28E-06 6.72E-09 8.69E-08 13 15 "AP2A1,AP2A2,AP1B1,CADPS,CLTC,SNAP91,SV2A,DNM1,LRRK2,STX1B,SYN1,SYP,SYT1" Pubmed 20301682 Hereditary Spastic Paraplegia Overview Pubmed 5.65E-12 1.30E-06 6.76E-09 8.73E-08 27 63 "ADAR,AMPD2,KIF1A,NIPA1,AP4M1,ATL1,BSCL2,REEP2,TUBB4A,AP4B1,GAD1,B4GALNT1,AP4S1,CPT1C,IBA57,KIF5A,L1CAM,ZFYVE27,PLP1,FA2H,SPART,DDHD2,AP4E1,DDHD1,KLC2,REEP1,GJC2" Pubmed 15229646 Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. Pubmed 5.77E-12 1.33E-06 6.87E-09 8.88E-08 15 20 "ASCL1,LHX2,DLX1,EMX2,ETV1,TBR1,GAD1,GRIA2,PAX6,ROBO1,RORB,SLIT1,NR2E1,SLC17A7,SLC17A6" Pubmed 20468064 Association study of 182 candidate genes in anorexia nervosa. Pubmed 6.55E-12 1.51E-06 7.76E-09 1.00E-07 50 182 "ADORA1,ADORA2A,ADRA1B,ADRB2,CALM1,CCK,CCKBR,CNR1,CALY,GPRASP1,DNM2,DRD1,EPB41L1,GPHN,PPP1R1B,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,GALR1,PPARGC1A,GNAS,GRIA1,GRIA2,GRIN1,GRM5,GABARAPL2,HTR2A,HTR5A,IGF1,KCNJ3,KCNN3,STMN1,NPY,NTRK2,PAH,ZDHHC8,PLIN1,QDPR,RGS10,TAC1,TACR1,TRH" Pubmed 28378742 Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Pubmed 6.71E-12 1.54E-06 7.91E-09 1.02E-07 236 1577 "SERPINA3,ACLY,RBM10,ACTN1,ADAR,FMNL2,ADD1,ESYT2,SORCS2,OSBPL8,FGD2,ASPH,ATP1A1,ATP1A2,EIF4G3,ATP2A2,ATP2B1,ATP2B3,MYOM1,DOCK11,NRP2,FUBP1,C1QC,CANX,HIP1R,CBLN1,INA,AIFM1,ARHGEF1,SYNGR3,ENTPD6,MYOM2,ARHGEF2,LRRFIP1,CLGN,COPB2,PLAA,COG1,CLU,MYL6B,CLTC,QKI,COL11A2,MAGED1,AHCTF1,NRG2,CP,RBM39,AKAP12,CRMP1,ANKRD44,SEC24C,CTNND1,PUM1,CYBB,DCAF8,MATR3,INTS1,DBN1,DBT,MYEF2,ELMO1,HP1BP3,POM121,DNM1,DNM2,DOCK2,DPYSL2,DNAJB6,FIS1,GOLT1B,EEF1D,EFNB3,EGFR,SORBS3,SRPK3,STARD3NL,MFSD10,EPB41L1,SPEG,ADGRV1,HSPA12B,TUBA1B,PTK2B,TUBB3,TUBB4A,RACK1,PRMT5,FGR,ATP5PD,SYNCRIP,RGPD5,FLNC,ANKFY1,NOP56,SMC2,FAM49B,ATP6V1H,MPP6,GAA,HBS1L,IQGAP2,GAP43,ERAP1,SEPT9,GART,TUBA8,AHDC1,COPS8,SPIN1,GLYR1,CBX1,GNAO1,GNAS,GP1BB,GPD2,TUBA1C,STMN2,C1QL4,GRM5,GSN,MAEL,MAN1B1,NCKAP1L,ATXN2L,HMGCL,HMGCR,HNRNPK,HP,HSP90AA1,IDH3B,IFI16,DOCK7,TUBB2B,JAK1,KIF5A,IPO5,MAT2A,MEST,MOV10,DBNL,MYBPC1,MYH3,MYH6,MYO5A,HNRNPM,NAP1L1,NCAM1,NCF2,NPR2,NUMA1,OGDH,PALM,PCDHGC3,PDGFRA,PFKFB3,FAM98B,PFKP,SSH1,PKM,NLE1,PLEC,PCDH18,PLTP,PPM1B,CRLS1,PRKACB,PRKAR1B,PRKCB,PRPH,PSMA6,PSMD13,PTH1R,PYGM,RAB5B,RFX4,RNH1,MYH14,EXD2,KLHDC8A,KIRREL1,PCMTD2,RPL15,RPL38,RPS20,SAFB,SEMA6D,ELMOD1,SFPQ,TRA2B,PUF60,MYO18A,DOCK10,HKDC1,SEC31A,SLC1A3,DHX30,SMTN,SEPHS1,SMARCA4,TTC17,RBM34,SON,BDP1,GLT8D1,CAND2,SPTAN1,TROVE2,SUPT5H,DNAJC9,MMS19,TCF12,PUM2,ARL10,TMPO,RBFOX2,TPM3,TUBB2A,SGK3,TUBB1,RPL7L1,UBE3A,UBTF,FLRT2,BCL2L13,VAV1,XPO1,CSDE1,TUBA1A,SIGLEC10,ITM2C,UBE3B,AAAS,FXR1,AP3B2,LAS1L" Pubmed 20798045 "Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex." Pubmed 7.20E-12 1.65E-06 8.44E-09 1.09E-07 24 51 "ATP2B3,CHN2,VAX2,PHF19,CALN1,DUSP9,ST8SIA3,NRN1,TUBB3,FGF11,DPYSL4,TBR1,B4GALNT1,CPLX1,GFAP,NEXMIF,PAX6,PFKP,POU3F2,PPP2R2C,RGS10,BCAN,SCN3B,SATB2" Pubmed 21826226 Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. Pubmed 7.26E-12 1.67E-06 8.47E-09 1.10E-07 16 23 "NUMB,PROM1,CALB2,ELAVL3,ELAVL4,EMX2,OLIG2,ERBB2,TUBB3,FOXG1,TBR1,MSI1,PAX6,RELN,SOX2,DICER1" Pubmed 12467588 Gamma protocadherins are required for survival of spinal interneurons. Pubmed 7.36E-12 1.69E-06 8.54E-09 1.10E-07 17 26 "ALCAM,CALB1,DLG4,GPHN,GAD1,GAP43,GFAP,GRIN1,MAP2,NCAM1,PCDHGC3,RELN,SYN1,SYP,TAC1,CNTN2,PCDHB15" Pubmed 23414517 A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. Pubmed 8.40E-12 1.93E-06 9.69E-09 1.25E-07 31 82 "ACTN2,CDC42BPA,DGKD,MYOM1,DST,CAPN3,MYOM2,DNAJB5,AKAP6,APPL1,DNAJB6,OPTN,SH3GLB1,FLNC,CAB39,HSP90AA1,LIMS1,BLOC1S2,MYBPC1,ZNF426,RDX,RYR1,ATXN1,SPTB,SYNE2,ANKRD28,DOCK9,AMOT,WIPF1,SH3GLB2,WIPF2" Pubmed 15741177 Tagging genes with cassette-exchange sites. Pubmed 9.91E-12 2.28E-06 1.14E-08 1.47E-07 70 308 "ZFAT,MAP4K3,CARS,ARHGEF2,SEPT7,ZMYM4,CHM,JAM2,KMT2C,PLAA,COL11A2,RBM39,NCOR1,NCOR2,PUM1,HDAC4,DDX46,RABGAP1L,EIF4G1,EN2,DMTN,WAC,SEPT9,MALT1,GLI2,STMN2,DIDO1,PRDM5,CIT,KAT7,MAT2A,MKLN1,AFDN,ZNF655,PLEC,TNPO2,PPP2R5E,PRKACB,MAPK3,QRICH1,PTK2,ENOX1,BSDC1,RNF220,SAFB,SFPQ,SCAF8,NTNG1,DHX30,TET1,ZNF423,ARHGAP26,CLASP2,PRRC2C,MMS19,SMG6,WDR7,DOCK9,ARHGEF12,PUM2,SIRT1,TNS1,NPL,ZNF346,ZMYND8,TOM1L2,SMARCAD1,CIAPIN1,NAV2,SOCS4" Pubmed 9734811 Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. Pubmed 1.01E-11 2.32E-06 1.15E-08 1.49E-07 35 102 "PPFIA3,HIP1R,ARHGEF2,MAP4K4,CRY2,AATK,OSBPL3,SOCS5,DZIP3,PPP6R2,HEPH,MFAP3L,MAGI2,ZC3H11A,POM121,SNAP91,G3BP2,ADGRV1,OGA,KIF21A,DOCK10,CLUAP1,CAND2,UHRF1BP1L,ARHGAP26,CLASP2,PHLDB1,ACSBG1,COBL,ASTN2,FBXW11,SIN3B,CLASP1,OBSL1,CRTC1" Pubmed 25631876 The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon. Pubmed 1.11E-11 2.54E-06 1.26E-08 1.62E-07 19 33 "SEMA6A,CALB2,LHX2,PLXNA4,EBF1,OLIG2,TUBB3,TBR1,NKX6-2,GBX2,NKX2-2,PAX6,SEMA5B,PTCH1,RFX3,ROBO1,ROBO2,SLIT1,SATB2" Pubmed 9455477 Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.21E-11 2.79E-06 1.37E-08 1.77E-07 24 52 "ADCY6,APAF1,GAS7,BSN,ZMYM4,PREPL,IPCEF1,SIPA1L1,SEC14L5,KIAA0408,GPRASP1,CTIF,DNAJC6,ZBTB24,SRGAP3,SGSM2,FEM1B,MBNL1,PLXNB1,ZHX3,ZBTB43,ARHGEF9,ATMIN,FLRT2" Pubmed 21491433 "Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala." Pubmed 1.22E-11 2.79E-06 1.37E-08 1.77E-07 31 83 "RASL11B,ATP1A2,BAIAP3,CALB1,VXN,NECTIN3,GREB1,TOX,OLIG1,DRD1,SEMA3D,ETV1,TBR1,GAD1,KIT,MAG,RSPO2,NFIA,PDE1C,PDYN,MAGEL2,RELN,RFX3,RORB,SMOC1,SST,ASTN2,TAC3,CHST8,SLC30A3,SPATA13" Pubmed 15328020 A screen for downstream effectors of Neurogenin2 in the embryonic neocortex. Pubmed 1.23E-11 2.82E-06 1.38E-08 1.78E-07 23 48 "ARHGAP5,CALB2,PTBP2,QKI,NIPBL,NCOR1,DCC,SRGAP3,ELAVL4,EPHA5,TUBB3,FUT9,GPM6B,STMN2,GRIK2,NEGR1,L1CAM,MAP2,MEF2C,PCDH9,NLGN1,SST,UNC5D" Pubmed 21565611 Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Pubmed 1.40E-11 3.23E-06 1.57E-08 2.02E-07 101 524 "ACTN1,CDC7,ERMN,WDR35,CC2D2A,OGT,EP400,EPB41L5,ASPH,DYNLL1,ATP1A1,ATP2A2,ATP6V1G2,CALB1,CALM1,AIFM1,CDH2,RAB3C,ZBED5,CLTA,MAP4K4,VCAN,CNTNAP2,CALY,ERC2,LIN54,DNAL1,DBN1,ZC3H11A,SEC16A,DNM1,DPYSL2,ANKRD13B,ABCA8,TUBA1B,TUBB3,FLNC,NEURL4,CAB39,CPLX1,GFAP,GOLGB1,TUBA1C,CNTRL,TPPP,GRB10,GSN,HBA1,HSP90AA1,KCNMA1,MAG,MAP2,MAP4,MAP6,DBNL,MSR1,MYO5A,NACA,HNRNPM,NAP1L1,NEFM,NKX2-2,PCBP3,NUCB1,PALM,PAX6,PFKFB2,PKD1,PKM,PLEC,STRN3,PRKACB,VPS13C,PSMA6,ANKHD1,PTPN13,QDPR,CEP97,RNH1,PCMTD2,ZC3H14,FAM161B,SMTN,NAPB,IFT122,CAND2,SPTAN1,STXBP1,SYN2,MMS19,KLHL4,RPGRIP1L,SIK3,TPM3,HSPBP1,TUBB2A,UCHL1,TUBA1A,NAV3,UBE3B,IFT88" Pubmed 17582329 Dlx transcription factors promote migration through repression of axon and dendrite growth. Pubmed 1.84E-11 4.22E-06 2.02E-08 2.61E-07 15 21 "ASCL1,NRP2,ELMO1,DLX1,DSCAM,ERBB4,GAD1,GAP43,HES5,MAP2,MAPT,MEF2C,PAK3,ROBO1,CADM1" Pubmed 19859539 Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. Pubmed 1.84E-11 4.22E-06 2.02E-08 2.61E-07 15 21 "ASCL1,CALB2,SLIT2,DCC,EPHB1,TUBB3,TBR1,GAD1,GFAP,L1CAM,MAP2,NPY,SNAP25,SATB2,SLC17A7" Pubmed 19075228 A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Pubmed 1.84E-11 4.23E-06 2.02E-08 2.61E-07 25 57 "ADGRF5,CASK,ASPH,ATP2B1,MYOM1,MTMR3,PTBP2,NCOR2,DTNA,MBNL2,FLNC,SORBS1,MPP6,ITGA7,MAP2,MBNL1,MEF2C,PPP3CA,CLIP1,KIF1B,FAM168A,R3HDM1,RBFOX2,ANO5,FXR1" Pubmed 19741146 A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. Pubmed 1.92E-11 4.41E-06 2.10E-08 2.71E-07 33 94 "ARNTL,FOXK1,LHX2,TBPL1,OLIG1,E2F5,E2F6,OLIG2,FOXM1,GFAP,GLUL,SOX21,HES5,MBP,MID1,NFIA,NFIX,NKX2-2,PDGFRA,PLP1,IRX1,RFX3,RFX4,RXRA,ZKSCAN3,SMARCE1,SOX2,SOX10,TCF4,TCF7L2,TCF12,NSD1,NR2E1" Pubmed 22632720 High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Pubmed 1.98E-11 4.55E-06 2.16E-08 2.79E-07 16 24 "ABHD6,DLG3,DLG4,NRN1,CACNG3,CACNG2,OLFM1,GRIA1,GRIA2,GRIA4,CPT1C,SHISA6,OLFM3,LRRTM4,VWC2,PORCN" Pubmed 20301317 Hereditary Ataxia Overview Pubmed 2.30E-11 5.29E-06 2.50E-08 3.23E-07 30 80 "ATM,ATP1A3,ATP2B3,CACNA1A,CACNB4,SACS,ATN1,FGF12,FGF14,NOP56,ELOVL5,TMEM240,KCNA1,KCND3,OPHN1,PDYN,PPP2R2B,PRKCG,APTX,LAMA1,ATXN1,ATXN2,ATXN7,SLC1A3,ELOVL4,TTBK2,VAMP1,PDSS1,TTPA,PDSS2" Pubmed 25640309 Systematic identification of molecular links between core and candidate genes in breast cancer. Pubmed 2.43E-11 5.57E-06 2.62E-08 3.38E-07 51 194 "MTA3,BCAR3,APC,MADD,ATM,ATP1A3,TTC9B,ADGRB1,CFL2,SULT4A1,PICK1,TCEAL2,BAG4,CRY2,GREB1,EEF1A2,ENO2,ERBB2,GMPR2,TUBB4A,FECH,ACTL6B,DKK3,SEPT9,GFAP,PCSK1N,GNAS,WIF1,HSP90AA1,STMN1,PLP1,PRKCB,KLK6,BCAS3,QDPR,FBXW7,BAALC,CASC3,ZNF821,SIRT2,SNCB,FAIM2,SOX2,BEX1,CLASP2,MAPK8IP3,SYN1,PDLIM2,UCHL1,MTCH1,TUBA1A" Pubmed 19056867 Large-scale proteomics and phosphoproteomics of urinary exosomes. Pubmed 2.46E-11 5.66E-06 2.64E-08 3.42E-07 165 1017 "SERPINA3,ACLY,ACTN1,NDRG3,ERMN,OSBPL1A,TAOK1,ALCAM,BBOX1,ALK,CDC42BPA,PPFIA2,ANXA7,APAF1,CPNE5,SHROOM2,PDXK,ARHGDIA,ARSE,ARSF,SLC4A4,ATP6V0A1,PROM1,AP1M1,C5,RAB29,CA4,CACNA2D1,CALB1,KALRN,SPAG9,CBR1,CD81,AP4M1,CDC42,SLIT2,SLC22A6,CLU,TPP1,CLTC,NIPBL,AHCTF1,CP,CDC42BPB,CREB5,CRYM,CST3,APPL1,CTH,ACY3,IST1,AIF1L,SIRPA,TIAM2,RUSC2,DNM2,ABI1,PDCD6IP,TOM1,GOLGA7,PLEKHA1,ENPP6,EPS8,ADGRV1,ACSL4,RACK1,BAIAP2,PCYOX1,IQCG,ANKFY1,DCTN2,SMC2,FAM49B,STAMBP,ATP6V1H,SDCBP2,GAA,CAB39,HBS1L,NCKAP1,IQGAP2,ALDH1L1,GFRA1,GK,COPS8,GLUL,GPD1,GPM6A,GRID1,GSN,KIF3A,PADI2,PACSIN2,DDX19B,ACOT7,HNMT,HP,SCIN,ITGAV,GATD1,KHK,KIFC3,LAMP2,GPR155,DBNL,MSRA,MYH3,MYO6,DNHD1,PDCD2,OLA1,ABCB1,DUSP26,PIK3C2A,PKD1,TMEM38A,PKM,PLCD1,PSAT1,PRKCZ,SLC26A11,VPS13C,CNTLN,PTPN13,EML5,PTPRO,RIPOR1,QDPR,RAB5B,RAP1GDS1,RDX,RNH1,MYH14,GSTCD,ROBO2,UEVLD,LRRK2,RYR1,FUZ,SHMT2,CNKSR2,SLC2A5,RAB3GAP1,SLC15A2,CDK5RAP2,MBD5,PBLD,GANAB,STXBP1,SYPL1,MGRN1,CUX2,ARHGEF12,TF,TGFBR3,SLC44A1,BHLHB9,STXBP4,TUBB2A,TOM1L2,SLC13A3,CRB2,TUBA1A,ITM2C,MVB12B" Pubmed 17913789 Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Pubmed 2.71E-11 6.24E-06 2.90E-08 3.75E-07 13 16 "CALB1,CALB2,ETV1,FABP7,TBR1,GAD1,NEFH,RELN,RORB,SLC1A3,CUX2,VLDLR,LRP8" Pubmed 11780052 The DNA sequence and comparative analysis of human chromosome 20. Pubmed 3.28E-11 7.54E-06 3.49E-08 4.51E-07 99 517 "EMILIN3,NDRG3,SLC12A5,ADRA1D,MYH7B,BCAS1,STX16,BMP7,NFS1,CBFA2T2,ENTPD6,CDC25B,CHGB,CHRNA4,COL9A3,RBM39,SLC32A1,MROH8,RIMS4,PHACTR3,CST3,PPP1R16B,CFAP61,SNPH,ZNF337,RASSF2,TM9SF4,SIRPA,SPATA2,ACOT8,EDN3,EEF1A2,SGK2,RBM12,EPB41L1,SIRPB1,HSPA12B,SEC23B,NOP56,NELFCD,ERGIC3,SDCBP2,ACSS1,GGT7,GNAS,DIDO1,PTPRT,TOX2,HRH3,DHX35,IDH3B,MYLK2,SCRT2,INSM1,KCNB1,KCNQ2,MYT1,NKX2-2,NNAT,OPRL1,PCSK2,PDYN,GDAP1L1,SMOX,PLTP,CRLS1,NKAIN4,VSTM2L,FITM2,DUSP15,TSPY26P,PCMTD2,SYNDIG1,FAM182A,KIF16B,BTBD3,ZNF334,NAPB,ELMO2,ARFGAP1,SNAP25,DOK5,ZHX3,DBNDD2,STAU1,SULF2,NSFL1C,PLCB1,CDH22,GZF1,TPD52L2,ZMYND8,TUBB1,SLC13A3,LAMP5,PMEPA1,XKR7,PAK5,FAM182B" Pubmed 15231748 Functional proteomics mapping of a human signaling pathway. Pubmed 3.67E-11 8.43E-06 3.88E-08 5.02E-07 109 591 "FMNL2,AP2A1,AP2A2,AP1B1,SPARCL1,ANK3,CASK,ARHGAP5,ARRB2,CDK13,CCDC181,STX16,DST,THSD7A,CANX,LDB2,FMNL3,ZBED5,ZFYVE9,SUMF2,RNF14,NCOR1,NCOR2,TRIM69,PDE4DIP,PHACTR3,PUM1,RUBCN,ZFYVE16,DCTN1,ZEB2,DNM2,DMTF1,PDCD6IP,TOM1,HIPK3,HEYL,OPTN,EBI3,EIF4G1,EIF4G2,CAMSAP1,CAP2,FLNC,NELFCD,ZMYND11,GLUL,HTATSF1,OS9,GOLGB1,SMAD1,SMAD9,MBD1,AFF1,AFDN,MYO6,PKD1,PLEC,EPN1,PPP2R5E,KANSL1,SYTL2,QRICH1,MTMR10,PLEKHB2,RBBP6,MORC4,RGS3,PBRM1,FAM161B,RXRA,ZFP2,SFPQ,ITSN1,EPN2,DHX30,LIMS2,SLC12A4,ATF7IP,ABTB1,SMARCE1,KIF13A,SON,SOX5,MYCBP2,PEG10,SPART,ERBIN,ST5,STAU1,KANK1,SUPT5H,ANKRD28,WASHC4,ARHGAP9,ZNF106,HEY1,TP53BP2,TPM2,ZMYND8,TTC3,UBC,CADM1,UBE3A,GORASP1,PITPNB,TOM1L2,ZBTB16,DOCK8" Pubmed 15604093 Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Pubmed 3.90E-11 8.97E-06 4.11E-08 5.32E-07 40 133 "ACTN1,ACTN2,NR0B1,NCOA1,KIF1A,CAMK2B,RGN,REPS2,RNF14,NCOR1,NCOR2,DCTN1,NR1D2,EEF1D,FOXO3,PCDH17,PPARGC1A,GLUL,NR3C1,GSN,CLASRP,GABARAPL2,HNF4G,MAP4,MAP6,NPY,NPPA,NUCB2,NECAB2,ING3,MED1,PROX1,RORB,RXRA,RXRG,SCG5,SHMT2,ITGB3BP,THRA,NR2C2" Pubmed 18617019 Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei. Pubmed 4.18E-11 9.61E-06 4.39E-08 5.67E-07 17 28 "SEMA6A,SEMA7A,NRP2,SLIT2,PLXNA4,SRGAP3,SEMA3D,PLXNC1,SEMA4D,SEMA5B,PLXNB1,ROBO1,ROBO2,SEMA6D,SLIT1,ROBO3,SEMA3B" Pubmed 15529118 Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation. Pubmed 4.50E-11 1.03E-05 4.70E-08 6.07E-07 14 19 "SYN3,APBB1,APLP1,APP,KIF5A,KLC1,MAPT,RAB3A,SYN1,SYN2,SYP,SYT1,KLC2,CAMK1G" Pubmed 25053427 Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Pubmed 4.63E-11 1.06E-05 4.81E-08 6.22E-07 25 59 "CDC42BPA,VAT1L,JAZF1,RUNX1T1,CHGA,CHGB,SPOCK2,CELSR3,FGF14,GHR,CELF3,INSM1,ERICH3,SCG3,NEUROD1,NHLH1,NKX2-2,NNAT,PAK3,PAX6,SNRK,ARX,SNAP25,MYT1L,SST" Pubmed 23359859 NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Pubmed 5.01E-11 1.15E-05 5.18E-08 6.69E-07 16 25 "SYNGR3,DLG3,RASGRP2,STX2,ACTL6B,GABBR1,GLRB,HNRNPK,NOVA1,NOVA2,RASGRF1,DZIP1,SLC4A3,SLC1A6,CDK5RAP2,SLC4A10" Pubmed 22768092 The biochemical anatomy of cortical inhibitory synapses. Pubmed 5.03E-11 1.15E-05 5.18E-08 6.69E-07 12 14 "NRXN1,GPHN,NBEA,GABRA1,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,NLGN3" Pubmed 23515096 Maturation of postnatally generated olfactory bulb granule cells depends on functional ?-protocadherin expression. Pubmed 5.25E-11 1.21E-05 5.39E-08 6.96E-07 15 22 "PCDHGB4,PCDHGC3,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1" Pubmed 11114734 The protein tyrosine kinase family of the human genome. Pubmed 6.75E-11 1.55E-05 6.90E-08 8.91E-07 30 83 "ALK,BTK,DDR1,AATK,CSF1R,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,FER,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,MATK,NTRK2,NTRK3,DDR2,PDGFRA,PTK2,RET,TEK,TIE1" Pubmed 18614564 Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Pubmed 7.20E-11 1.65E-05 7.32E-08 9.45E-07 44 158 "AP2A1,AP1B1,CASKIN1,KCNAB2,BCAS1,DYNLL1,ATP6V0A1,CAMK2A,CAMK2B,CAMK2D,INA,CLTC,CNTN1,NTM,EPB41L2,TUBB3,TUBB4A,ATP5PD,AGAP2,DCTN2,BRSK1,GLUL,GNAO1,TPPP,LSAMP,MAP2,MAP4,MAP6,MARK1,MYO5A,NDUFA5,OPCML,TMOD2,NDUFS7,SLC1A2,SLC1A3,SNCA,SPTAN1,EPB41L3,STX1A,STXBP1,SYP,ICAM5,KCNAB1" Pubmed 25814554 Phospho-tyrosine dependent protein-protein interaction network. Pubmed 7.33E-11 1.68E-05 7.42E-08 9.58E-07 83 410 "OSBPL6,C1QTNF3,BCAR3,MYH7B,CCDC74A,NUMB,BTK,SCAPER,CA8,KRIT1,USP2,LRRFIP1,SOCS6,CHN2,PLEKHB1,KMT2C,NGEF,LETMD1,SH2B1,APPL1,NOS1AP,DCAF8,DBN1,ZBTB24,PARD6A,RABGAP1L,WDR20,OLIG1,DTNA,E2F6,PHC2,ASB3,ING4,TNK2,EPS8,FABP7,FER,FGF12,FGF13,BAIAP2,SEMA4D,WDR83,FYB1,FYN,ZMAT1,MYOZ2,CYP46A1,AHDC1,LNX1,PRRC2B,TUBA1C,GRB10,LIX1,MATK,BEX5,NME4,PDPK1,ANLN,PIK3R1,ZNF655,PPARA,VSTM2L,PTK2,KCTD17,GSTCD,SH3BP2,ARFGAP1,DOK5,ZHX3,SPTB,NXT2,NACAD,MLST8,OBSL1,TNS2,LEFTY2,TNS1,TSC1,CCDC14,ANKS1B,SHD,MSRB3,SOCS4" Pubmed 16701208 A shared vesicular carrier allows synaptic corelease of GABA and glycine. Pubmed 7.55E-11 1.73E-05 7.57E-08 9.78E-07 11 12 "SLC12A5,SLC32A1,RIMS2,GPHN,GABRA1,GAD1,GAD2,MAP2,RIMS1,SYN1,SLC17A6" Pubmed 16980967 NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Pubmed 7.55E-11 1.73E-05 7.57E-08 9.78E-07 11 12 "LRRC4C,DLG2,DLG3,DLG4,NTNG2,LRRC4B,MAP2,NTNG1,LRRC4,SYP,SLC17A7" Pubmed 23453885 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Pubmed 9.04E-11 2.08E-05 9.03E-08 1.17E-06 26 65 "AS3MT,ANK3,CACNB2,NEURL1,MAP4K4,TENM4,SLC45A1,HDAC4,ZNF804A,MPP6,GRIK1,KIF5C,MMP16,NTRK3,PPP2R2B,CNNM2,KIF21B,GLT8D1,TCF4,SYNE1,ZFPM2,CSMD1,ANO5,FAM155A,ANKS1B,SLC17A6" Pubmed 16186258 Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. Pubmed 9.19E-11 2.11E-05 9.14E-08 1.18E-06 17 29 "CASKIN1,PPFIA2,PPFIA1,PPFIA3,CASK,CDH2,NRXN1,DLG4,ERBB4,GRIA2,GRIA4,NLGN3,RAB5B,NLGN1,SNAP25,STXBP1,SYP" Pubmed 15123239 An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies. Pubmed 9.54E-11 2.19E-05 9.44E-08 1.22E-06 30 84 "ABR,ACTN1,ACTN2,ADRA1D,APC,CASK,ATP2B1,ATP2B2,ADGRB2,ADGRB3,ARHGEF7,MTMR2,GDA,FOXO3,PRLHR,GRIN2C,GUCY1A2,ADAMTS6,KCNA4,KCNJ4,KCNJ10,LMO1,MAP4,MPP2,MAPK12,SLC1A7,SSTR1,ERBIN,NR2E1,VIPR2" Pubmed 22586326 Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Pubmed 9.86E-11 2.27E-05 9.72E-08 1.26E-06 116 653 "ABCF1,ACLY,ACTN1,ARID1A,AP1B1,OSBPL8,ARHGDIA,CCAR2,ATM,ATP1A1,EIF4G3,ATP2A2,KIF1A,BLM,DST,CANX,SPAG9,INA,COPB2,CLTC,TJP2,HECTD1,NIPBL,AHCTF1,RBM39,SEC24C,PUM1,GAPVD1,INTS1,MYEF2,HP1BP3,CEP170,ZC3H11A,DDX46,SEC16A,MED12,DNM2,DPYSL2,PDCD6IP,SUGP2,EIF4G1,EPB41L2,SRRM1,TUBB4A,RACK1,PRMT5,SEC23B,SYNCRIP,FLNC,ZNF512,STAG2,NCKAP1,GART,GLYR1,ZNF638,PRRC2B,TUBA1C,DIDO1,ATXN2L,DOCK7,IPO5,MAP4,AFDN,MOV10,MYO5A,NAP1L1,NEFM,NF1,NUMA1,PFKP,XRN1,NLE1,PLEC,EXOSC10,ANKHD1,USP47,PBRM1,RNH1,MYH14,RPL15,ZC3H14,RPL38,SBF1,SFPQ,PUF60,DHX30,SMARCA4,SMARCC2,RBM34,SON,ZSWIM8,MYCBP2,ZC3H13,SPTAN1,POGZ,EPB41L3,LARP4,STAU1,GANAB,SUPT5H,PRRC2C,SYNE2,ANKRD28,NSD1,FRYL,DICER1,TJP1,TP53BP1,UBTF,NSD2,XPO1,CSDE1,HNRNPA3,NUP214,FXR1,LAS1L" Pubmed 17678855 Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Pubmed 1.05E-10 2.41E-05 1.01E-07 1.31E-06 13 17 "ASCL1,DLX1,OLIG1,OLIG2,TUBB3,GAD1,STMN2,MBP,NKX2-2,PDGFRA,PLP1,PTCH1,SOX10" Pubmed 28864826 IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2?. Pubmed 1.05E-10 2.41E-05 1.01E-07 1.31E-06 13 17 "NRXN2,SLC32A1,DLG4,GPHN,GABRA1,GABRG2,GRIA1,IGSF21,NLGN3,NLGN1,SYN1,SYP,SLC17A7" Pubmed 17554007 "Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo." Pubmed 1.05E-10 2.41E-05 1.01E-07 1.31E-06 13 17 "CALB1,CALB2,TUBB3,SEMA4D,GAD1,GAP43,GFAP,NCAM1,NEUROD1,PLXNB1,PROX1,TAC1,CNTN2" Pubmed 15822905 Phosphoproteomic analysis of synaptosomes from human cerebral cortex. Pubmed 1.05E-10 2.41E-05 1.01E-07 1.31E-06 13 17 "ADD1,SV2A,GPM6A,TPPP,HSP90AA1,MAP2,MAPT,NCAM1,NEFM,PKN2,SLC1A2,STX1A,SYN1" Pubmed 20825492 ERK1 and ERK2 are required for radial glial maintenance and cortical lamination. Pubmed 1.05E-10 2.41E-05 1.01E-07 1.31E-06 13 17 "ASCL1,CALB1,OLIG2,TBR1,GAD1,GFAP,MBP,PDGFRA,MAPK3,RELN,S100B,SLC1A3,SST" Pubmed 19799774 Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Pubmed 1.07E-10 2.45E-05 1.03E-07 1.33E-06 27 70 "APP,CAMK2A,CHGB,IPCEF1,CYBB,SIRPA,ELAVL3,PPP1R1B,ACTL6B,UBE2E3,GSTM5,HBA1,MAPT,MBP,NEUROD1,PLP1,SEPT4,PPP3CA,RGS4,ROBO1,RORB,FAM81A,SNCB,SOX11,CAND2,KIAA0930,RBFOX2" Pubmed 16033648 A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Pubmed 1.28E-10 2.94E-05 1.22E-07 1.58E-06 64 285 "RBM10,ADAR,ADARB2,TNRC6C,SYNJ2,FUBP1,PTBP2,SRSF11,QKI,RBM39,PUM1,PABPC5,MYEF2,KLHL3,ALKBH8,G3BP2,CPEB2,RBM12,ELAVL2,ELAVL3,ELAVL4,POLR1B,SYNCRIP,ZCCHC17,KHDRBS3,STAU2,PPARGC1A,RNPS1,TNRC6A,ZNF638,HTATSF1,TDRKH,NUDT21,HNRNPK,CELF5,MSI1,HNRNPM,CNOT4,NOVA1,NOVA2,PCBP3,ANKHD1,KHDRBS2,RAVER2,SAFB,SFPQ,TRA2B,SCAF8,DHX30,RUFY2,SLC6A8,CPEB4,RBM34,SON,PEG10,RBM26,STAU1,PUM2,PRMT8,CELF4,TFIP11,PCBP4,NELFE,FXR1" Pubmed 20943929 "The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence." Pubmed 1.33E-10 3.04E-05 1.26E-07 1.63E-06 18 33 "SEMA6A,NRP2,CDH8,LHX2,EBF1,EMX2,OLIG2,TUBB3,TBR1,NKX6-2,GBX2,PAX6,PDGFRA,RELN,PTCH1,RORB,SOX5,SATB2" Pubmed 18187620 Identification of host proteins required for HIV infection through a functional genomic screen. Pubmed 1.52E-10 3.49E-05 1.44E-07 1.86E-06 62 273 "XKR4,TAOK1,SMIM29,PHF12,BRINP2,ATP6V0A1,ST3GAL5,CACNG1,HIP1R,CCNT1,USP6,DLGAP1,RAB28,C4orf33,NCOR2,RIMS4,ARHGAP32,GAPVD1,DNAL1,TIAM2,RUSC2,ALKBH8,EDNRA,TMTC1,EGFR,KMT5B,STARD3NL,RABEPK,EPS8,RRAGB,TMEM132C,AGAP2,RGPD5,GCK,MMADHC,HTATSF1,RAPGEF1,GABARAPL2,AGBL5,SOWAHA,ITPKA,JAK1,MAP4,NCR3LG1,ERI2,KCNIP3,SEC14L1,ANKRD6,KDM4D,WDTC1,SPTAN1,SEPT8,STAC2,FBXW11,ARHGEF12,FAM200B,DOK6,CLDND1,DHX33,WNK1,TMEM163,RNF170" Pubmed 24658140 The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Pubmed 1.58E-10 3.63E-05 1.49E-07 1.93E-06 39 133 "APBB2,APP,ARRB1,ARRB2,ARHGEF7,CALM1,SOCS6,SH2B1,CTNND1,PDCD6IP,EGFR,EPS8,ERBB2,ERBB4,BAIAP2,FGR,GAB1,GABBR1,WASF3,GRB10,RAPGEF1,NR3C1,HSP90AA1,MAPT,NTRK2,PDGFRA,PRKCZ,MAPK8,MAPK9,PTK2,RET,RGS4,SH3GL2,SH3GL3,SHC4,SLA,SNCA,VAV1,TUBA1A" Pubmed 25281560 Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. Pubmed 1.70E-10 3.90E-05 1.60E-07 2.07E-06 113 636 "SDE2,PWWP2A,AP2A1,ZNF608,ZNF687,EP400,PARG,SHTN1,MIER1,ARRB2,BARD1,DST,ARHGEF7,WASF1,SPAG9,MAP7,PRC1,LRBA,EPS15L1,ARHGEF6,CP,CHD1L,FAM169A,DZIP3,EDRF1,ZFYVE16,GIT2,DBT,ZBTB24,KIAA0753,CEP170,MED24,SEC16A,USP3,MED12,DYRK1A,PHC2,EPB41,SRRM1,F5,KAT8,CAMSAP1,ATP5PD,CAP2,FOXM1,NOP56,DCTN2,PDLIM5,ATP6V1H,ZNF512,C15orf41,SRCAP,BRD8,RNPS1,GLYR1,MSL3,ZNF638,GNAO1,KIF3A,KAT7,MSL1,RBPJ,DOCK7,KIF5A,GIT1,NASP,ODF2,ANLN,XRN1,PMS2,MED1,GON4L,ARID4A,DPF2,RFX5,UBR7,KIF7,PBRM1,MYH14,CCDC25,SCP2,SUPT20H,TRA2B,EPC1,KDM4B,MYCBP2,ERC1,SPTAN1,SPART,EPB41L3,ERBIN,NSFL1C,DNAJC9,TCEA1,CBX5,ACTR6,ZFP91,CABIN1,TP53BP2,TPD52,TPD52L2,METTL3,HSPBP1,HIRA,AMOT,CCDC14,NSD2,XRCC4,ZNF711,SH3GLB2,WNK1,TUBA1A,FIP1L1" Pubmed 18603407 Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum. Pubmed 1.93E-10 4.43E-05 1.81E-07 2.34E-06 17 30 "CALB1,CALB2,CCNH,TUBB4A,GRIN1,GRIN2C,GRIN2D,OPALIN,KNDC1,KCNC1,MOBP,PENK,PRKCG,SLC1A3,SST,ZIC1,TUBA1A" Pubmed 20398908 Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Pubmed 2.01E-10 4.62E-05 1.88E-07 2.43E-06 26 67 "DGCR6,ACHE,ACTN2,FZD9,NIPA1,NRXN3,NOS1AP,DLG2,NRG3,GABBR1,GALR1,DISC1,GRIA1,GRIA2,GRM5,GRM7,GRM8,PLCD1,PPP3CC,PRODH,S100B,NLGN1,SLC1A2,TACR1,TRH,TFIP11" Pubmed 20211142 An atlas of combinatorial transcriptional regulation in mouse and man. Pubmed 2.05E-10 4.72E-05 1.91E-07 2.47E-06 140 846 "KDM5D,MRTFA,BIN1,APC,ARNTL,ASCL1,ZSCAN18,BACH1,BARD1,RUNX1T1,LDB2,CERS5,CBFA2T2,CNOT8,LHX2,VAX2,FHL5,TBPL1,ZFP28,RBM39,RNF14,NCOR2,PHF14,PYGO1,HDAC9,HDAC4,MAML1,ZEB2,ZBTB24,ARNT2,DLX1,OLIG1,EBF1,HEYL,SUGP2,ASB3,ELAVL2,ING4,EMX2,DENND4A,POLR1B,FOXG1,FOXM1,DACH2,ZMYND11,NKX6-2,ZNF274,CSDC2,PPARGC1A,ZNF276,RNPS1,TOX3,KDM2B,INSM2,NR3C1,PRDM5,ZNF496,HLF,HNF4G,TLX1,ZDHHC15,ZNF546,LMO1,LMO2,SMAD1,MBD1,MEF2C,MEIS1,MEIS2,MITF,ZNF92,MXI1,MYCN,NAP1L2,NEUROD1,NFE2L2,NFYA,NKX2-2,PAX6,PBX1,PRRX1,POU3F4,POU6F1,PPARA,MED1,PROX1,ZSCAN32,ZSCAN2,DPF2,RFX2,RFX3,RFX4,CARF,RORB,SOX8,KCNIP3,RXRA,RXRG,HES6,ZFP2,SOX6,ZFP30,ANKRD6,PKNOX2,SIRT2,SCMH1,ABTB1,SMARCE1,KDM4B,SOX2,SOX15,SP2,KDM4C,ZBTB43,SUPT5H,MMS19,TAL1,TBL1X,TBX15,TCF4,TCF7,TCF12,SIRT1,THRA,RBFOX2,ZNF384,TRPS1,SSBP2,ZKSCAN5,UBTF,ZIC1,ZIC2,ZNF23,ZNF24,ZNF70,ZBTB16,ZNF184,ZNF195,MEIS3,CSDE1" Pubmed 28705898 Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Pubmed 2.06E-10 4.73E-05 1.91E-07 2.47E-06 37 123 "AXIN2,SEMA6A,CACHD1,CALB1,CRLF1,TMEM59L,COL9A3,CTNND2,ARNT2,PPP1R1B,KHDRBS3,NSG1,GFRA1,KDM2B,PSRC1,B4GALNT4,MFSD2A,WIF1,ACOT7,NKD1,STMN1,MEST,MYCN,FXYD6,NASP,NNAT,SERPINE2,NKAIN1,RET,SOX8,C18orf54,TMPO,DOK6,CADM1,RPRM,VLDLR,PCBP4" Pubmed 23455924 A Y2H-seq approach defines the human protein methyltransferase interactome. Pubmed 2.11E-10 4.84E-05 1.94E-07 2.51E-06 72 342 "INTS2,MYH7B,CCDC74A,MTMR9,SOCS6,QKI,CCDC151,ZFP28,PDE4DIP,PYGO1,KIAA0408,DCAF8,PHF19,CENPL,RASSF2,ZBTB24,SRGAP3,NR1D2,PHC2,PHF20L1,ASB3,ING4,PRMT5,BAIAP2,SYNCRIP,NELFCD,WDR83,ZCCHC17,AK8,FYN,STARD10,MALT1,SPIN1,GLYR1,LNX1,NUDT21,ATE1,RASSF8,DOCK7,KIFC3,SMAD9,RSPO2,NFIX,NME4,NECAB2,PPARA,KANSL1,RAD17,KCTD17,RPRD1A,GSTCD,OGDHL,RCOR3,KDM4B,KDM3A,DIP2A,MLC1,JMJD6,TACC1,MLST8,C18orf54,ITGB3BP,NR2C2,PRMT8,TSC1,ZKSCAN5,CCDC14,SH3GLB2,DNALI1,FIP1L1,JMJD1C,FRMD6" Pubmed 20562859 Network organization of the human autophagy system. Pubmed 2.20E-10 5.06E-05 2.02E-07 2.62E-06 85 433 "EMILIN3,ESYT2,OSBPL8,TAOK1,ASPH,CCAR2,DYNLL1,ALDH7A1,DCAF5,FOXK1,CALM1,BRSK2,CBR1,INA,COPB2,CLTA,CLTC,TJP2,CSNK1G3,DZIP3,CTNND1,RUBCN,RASSF2,RABGAP1L,DNM2,PDCD6IP,FARSB,SH3GLB1,EIF5,CEP78,STRADA,SEC24B,PRKAG2,SEC23B,VTI1B,FOXO3,FLNC,ANKFY1,UFM1,CAMKK2,CAB39,IQGAP2,SEPT9,FREM1,GYG1,ATG4C,GABARAPL2,IDH3A,IPO5,NCOA7,MAP4,PTOV1,NEFM,PCMT1,PDPK1,PFKP,PIK3C2A,PRKAB2,ATG16L1,SEC61A2,MCMBP,SAFB,SARS,FNIP1,SHMT2,AMBRA1,RAB3GAP1,WDTC1,FNBP1,ERC1,RBM26,GANAB,MLST8,OBSL1,TJP1,TMPO,TP53BP2,TSC1,AMOT,TBC1D15,XPO1,ZNF24,SH3GLB2,CAB39L,GAN" Pubmed 18227507 Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Pubmed 2.29E-10 5.26E-05 2.10E-07 2.71E-06 12 15 "NLGN4X,DLG4,GPHN,GRIN1,NLGN3,NLGN4Y,NLGN1,SNAP25,VAMP1,SYP,SLC17A7,SLC17A6" Pubmed 19243017 Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Pubmed 2.42E-10 5.56E-05 2.21E-07 2.85E-06 23 54 "SEMA6A,PROM1,RUNX1T1,ADGRG1,PLXNA4,EBF1,HEYL,FRY,HSPA12B,WIF1,KCNA1,AFDN,NEUROD1,NF1,TMOD2,RGS3,SEMA6D,SEPT3,TMEM178B,HEY2,TUBB1,ZIC1,NDRG4" Pubmed 20392955 Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. Pubmed 2.64E-10 6.07E-05 2.40E-07 3.10E-06 16 27 "CALB1,CALB2,SLC32A1,TIAM2,DLX1,ERBB4,TUBB3,TBR1,GAD1,GUCY1A1,MAP2,NPY,RELN,RXRG,SST,TAC1" Pubmed 11756498 Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. Pubmed 2.96E-10 6.79E-05 2.67E-07 3.46E-06 19 38 "ABR,PLEKHG5,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ITSN1,FGD4,ARHGEF9,MCF2L,ARHGEF12,TIAM1,VAV1,VAV2" Pubmed 26930384 "Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun." Pubmed 2.99E-10 6.86E-05 2.69E-07 3.48E-06 38 130 "EMILIN3,ADCY5,ATP1A2,MYOM1,AKAP6,AKAP12,CRMP1,LRIG1,BOC,MYADM,ABI2,NCALD,EFS,MRVI1,FOXF2,SORBS1,ADAMTS8,ACOT7,NKD1,MAPT,MEF2C,NCAM1,NELL2,NF1,DDR2,PSD,PTN,KCNIP1,SMTN,SLC8A1,FNBP1,ZNF423,TAL1,HHIP,THBS4,ZIC3,RGMA,FZD3" Pubmed 25402006 In silico prediction of physical protein interactions and characterization of interactome orphans. Pubmed 3.28E-10 7.53E-05 2.94E-07 3.80E-06 39 136 "APBB2,APP,ARRB1,ARRB2,RIPK1,ARHGEF7,CALM1,SOCS6,SH2B1,CTNND1,PDCD6IP,EGFR,EPS8,BAIAP2,FGR,GAB1,WASF3,GRB10,RAPGEF1,NR3C1,HSP90AA1,MAPT,NTRK2,PDGFRA,PRKCZ,MAPK8,MAPK9,PTK2,RET,RGS4,SH3GL2,SH3GL3,SHC4,SLA,SNCA,TCF4,VAV1,ZIC3,TUBA1A" Pubmed 27480238 SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Pubmed 3.34E-10 7.66E-05 2.95E-07 3.81E-06 15 24 "LRFN2,LRFN1,CASK,DLGAP1,MAGI2,DLG2,DLG3,DLG4,GRIA1,GRIA2,GRIN1,MAPK3,LRFN5,SYN1,SYP" Pubmed 18794345 The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Pubmed 3.34E-10 7.66E-05 2.95E-07 3.81E-06 15 24 "CDK5R1,CALB2,ETV1,TBR1,HES5,MAP2,NEFH,NEUROD1,PAX6,POU3F2,RELN,SOX1,SOX2,SATB2,CUX2" Pubmed 24507192 Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain. Pubmed 3.34E-10 7.66E-05 2.95E-07 3.81E-06 15 24 "APC,CALB2,SLC32A1,DLX1,OLIG1,OLIG2,GPHN,TBR1,GAD1,GFAP,MBP,NPY,PLP1,SOX10,SST" Pubmed 22534482 Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas. Pubmed 3.34E-10 7.66E-05 2.95E-07 3.81E-06 15 24 "CACNA1A,CACNA1B,CACNA2D1,CLCN3,CACNG3,GABRB1,GABRG2,GRIA4,GRIK1,GRIK2,GRIK5,KCNA4,KCNQ3,SCN2B,SCN3B" Pubmed 16309667 Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Pubmed 3.44E-10 7.91E-05 3.03E-07 3.92E-06 13 18 "SLIT2,DCC,EMX2,FGFR1,FGFR3,FOXG1,TBR1,GAP43,GFAP,PAX6,ROBO2,CNTN2,CUX2" Pubmed 23793025 Genome-wide meta-analysis identifies new susceptibility loci for migraine. Pubmed 3.47E-10 7.98E-05 3.05E-07 3.94E-06 28 78 "ADARB2,ADRA1B,TRMT9B,FHL5,CTIF,RABGAP1L,MRPL37,EYA1,MRVI1,NBEA,SORBS1,GFRA1,GFRA2,ATF7,NR3C1,HPSE2,MMP16,CTNNA3,KSR2,CNNM2,PTPRD,SUGCT,LIMCH1,KANK1,AJAP1,ASTN2,NSD1,TSC1" Pubmed 25708312 "Early growth response 1 (Egr-1) directly regulates GABAA receptor ?2, ?4, and ? subunits in the hippocampus." Pubmed 3.73E-10 8.56E-05 3.24E-07 4.19E-06 14 21 "SLC32A1,DLG4,GPHN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GAD2,GRIA1,SYN1,SYP" Pubmed 26494785 FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Pubmed 3.73E-10 8.56E-05 3.24E-07 4.19E-06 14 21 "KCNT1,DPP10,NGEF,CNR1,ELAVL4,RASGRP2,DNER,KCND2,HCN1,CNTNAP3,RYR1,SPHKAP,MTCL1,FBXL16" Pubmed 26745185 The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Pubmed 3.78E-10 8.68E-05 3.27E-07 4.23E-06 23 55 "SLC12A5,ASCL1,ATM,PROM1,EGFR,OLIG2,TUBB3,FGFR3,DLL3,TBR1,GABRA1,GFAP,GLI2,MAP2,MBP,NKX2-2,PAX6,PDGFRA,SNAP25,SOX2,SYP,SATB2,TP53BP1" Pubmed 27806288 Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Pubmed 3.88E-10 8.92E-05 3.34E-07 4.32E-06 17 31 "APC,CDH2,ZEB2,OLIG2,FGFR3,ALDH1L1,GFAP,NFIA,NKX2-2,PAX6,PDGFRA,PLP1,RELN,SLIT1,SOX2,SOX10,ZEB1" Pubmed 10767319 Dissection of behavior and psychiatric disorders using the mouse as a model. Pubmed 3.88E-10 8.92E-05 3.34E-07 4.32E-06 17 31 "APP,CALB2,CAMK2A,CHRNB2,GABRB3,GRIA1,GRM5,NCAM1,NTRK2,PAH,PPP3CA,PRKCG,PRODH,RYR3,ATXN1,UBE3A,KCNAB1" Pubmed 11853319 Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. Pubmed 4.40E-10 1.01E-04 3.77E-07 4.88E-06 22 51 "UNC5A,CCAR2,DIS3L,FAM171B,EARS2,YTHDC1,GRIN3A,ADGRV1,KIAA1958,C2CD4C,SH3TC2,ATP8B4,SGSM1,FNIP1,TMEM132D,ZFP90,AZIN2,AKNA,ANKRD24,ZNF17,AMZ1,RSPRY1" Pubmed 16814779 "Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family." Pubmed 4.47E-10 1.03E-04 3.77E-07 4.88E-06 11 13 "CALB1,SLC32A1,DLG4,SEZ6L2,SEZ6,GRIA1,GRIA2,GRIK5,GRIN1,SEZ6L,SLC17A7" Pubmed 16880397 From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Pubmed 4.47E-10 1.03E-04 3.77E-07 4.88E-06 11 13 "CALB2,GAP43,GRIA1,GRIA2,GRIA4,GRIN1,L1CAM,MAP2,RELN,SLC1A2,SLC1A3" Pubmed 19892785 Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon. Pubmed 4.47E-10 1.03E-04 3.77E-07 4.88E-06 11 13 "CALB1,CALB2,CCK,MBP,NF1,OMG,STX1B,SNAP25,SST,STX1A,RTN4" Pubmed 27223325 NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Pubmed 4.47E-10 1.03E-04 3.77E-07 4.88E-06 11 13 "SLIT2,DCC,EPHA5,L1CAM,NEFH,NOVA1,NOVA2,ROBO2,NTNG1,SYP,CNTN2" Pubmed 22923088 The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Pubmed 4.75E-10 1.09E-04 4.00E-07 5.16E-06 24 60 "AXIN2,ASCL1,FGF17,NRP2,BMP7,CALB2,CDH8,LHX2,ELAVL4,EMX2,EPHB1,ETV1,FOXG1,TBR1,GRIK4,HES5,L1CAM,RSPO2,PAX6,PROX1,RELN,RORB,SATB2,CUX2" Pubmed 12376548 "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway." Pubmed 5.25E-10 1.21E-04 4.40E-07 5.69E-06 20 43 "ABR,PLEKHG5,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF4,TIAM2,MAPK8,RASGRF1,RASGRF2,ITSN1,FGD4,ARHGEF9,ARHGEF12,TIAM1,VAV1,VAV2" Pubmed 17470284 Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. Pubmed 5.61E-10 1.29E-04 4.67E-07 6.04E-06 16 28 "ASCL1,LHX2,DLX1,EMX2,ETV1,TUBB3,FOXG1,TBR1,GAD1,NKX6-2,GAP43,PAX6,RELN,ROBO1,RORB,CUX2" Pubmed 27568567 "Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function." Pubmed 5.61E-10 1.29E-04 4.67E-07 6.04E-06 16 28 "ASPA,CCKBR,CHRM4,DRD1,GALR1,GFAP,GJB1,KCNJ10,MAG,MOBP,OXTR,FA2H,EPB41L3,TCF4,UGT8,GJC2" Pubmed 20360068 Systematic analysis of human protein complexes identifies chromosome segregation proteins. Pubmed 5.75E-10 1.32E-04 4.77E-07 6.16E-06 176 1149 "ARID1A,AP2A1,BEGAIN,OGT,APC,ARRB1,ARRB2,CCAR2,DYNLL1,ATM,AZGP1,BACH1,BCL7A,BLM,SYNJ2,CACNA2D1,CANX,SPAG9,PRC1,AIFM1,C1orf52,CDC25B,CDC27,ZMYM4,LRWD1,COPB2,CNOT8,EPS15L1,PLAA,CLU,CLTC,ABCG2,NIPBL,HOMER3,AHCTF1,NSL1,CPS1,PNKD,RBM39,AKAP12,CRY2,TRIM69,CSNK1E,DCAF4,GAPVD1,DCAF8,LIN54,MATR3,AIF1L,DCTN1,COPS7A,CEP170,DDX46,PARD6A,FAM107B,PDCD6IP,EDIL3,PHF20L1,EIF4G1,COPS4,DCTN4,VPS13B,GPHN,TUBA1B,RACK1,CEP78,PRMT5,KAT8,FECH,MAD2L2,SYNCRIP,RGPD5,NOP56,DCTN2,TACC2,SPECC1,FYN,NEURL4,STAG2,GATM,TUBGCP4,WASHC2A,BRD8,MSL3,CBX1,HTATSF1,GNAL,GNAO1,GNAS,PRRC2B,HMGB1,HNRNPK,HP,DHX35,HSF2,HSP90AA1,MSL1,KIFC3,IPO5,PAXBP1,SYTL4,LYPLAL1,POC1B,MOV10,NACA,PCBP3,NUMA1,CHAMP1,OGG1,PDE4D,ANLN,CCSER2,PKM,STRN3,RETREG2,SH3KBP1,PPP2R5C,PPP2R5E,KANSL1,PYGM,PPP2R3C,CEP97,USP47,BSDC1,DPF2,PBRM1,TCP11L1,CLIP1,ZNF331,RMI1,SFPQ,TRA2B,COPZ1,AMBRA1,DHX30,SMTN,KANSL3,ZFP1,SMARCA4,SMARCC2,CDK5RAP2,SMARCE1,RCOR3,WDTC1,UHRF1BP1L,CLASP2,POGZ,SS18,NCDN,MPRIP,TTBK2,KANK1,GANAB,ZC3H4,MTCL1,WASHC4,CLASP1,SYNE1,TF,SIRT1,ZNF106,TJP1,TMPO,KCTD2,TP53BP1,TPM1,STXBP4,TRPS1,GORASP1,XPO1,TFIP11,CSDE1,STOX2,MRPL47,HNRNPA3,NUP214" Pubmed 25241761 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. Pubmed 6.29E-10 1.45E-04 5.20E-07 6.72E-06 75 371 "ACTN1,ADCY2,APC,APP,ARRB2,NUMB,BID,CFLAR,CAMK2A,CAMK2G,CANX,RUNX1T1,CD86,CDC42,TAOK2,CLTC,ARHGEF6,CSF1R,CSF2RA,CSNK1E,APPL1,DAPK1,DOCK2,DUSP9,EGFR,ERBB2,ECSIT,F3,F8,PTK2B,FCGR1A,FCGR3A,STRADA,FGF1,FGFR1,FOXO3,FLT1,FYN,GAB1,CAB39,GHR,GNAS,GRM5,HSPA1L,KIT,SMAD1,KITLG,CTNNA3,NTRK2,PDGFRA,PDPK1,PIK3R1,PKM,PPM1B,PPP2R5C,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,PTK2,RALGDS,RET,RPS6KA2,RXRA,MAPK12,SNCA,SPP1,TAB2,FBXW11,TBL1X,PARD3,PIK3R5,RICTOR,ZBTB16" Pubmed 14534257 "The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion." Pubmed 7.17E-10 1.65E-04 5.86E-07 7.58E-06 10 11 "OLIG1,OLIG2,SEMA4D,MAG,MBP,MOG,PDGFRA,PLP1,PLXNB1,RTN4" Pubmed 21119615 DGK? regulates presynaptic release during mGluR-dependent LTD. Pubmed 7.17E-10 1.65E-04 5.86E-07 7.58E-06 10 11 "DGKI,DLG2,DLG3,DLG4,GPHN,GAD2,MAP2,NEFH,SHANK2,SYN1" Pubmed 15882093 Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1. Pubmed 7.17E-10 1.65E-04 5.86E-07 7.58E-06 10 11 "ASCL1,DLX1,TUBB3,PPP1R1B,PAX6,POU3F4,ROBO1,SOX1,SOX2,SOX3" Pubmed 12466305 "Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set." Pubmed 7.20E-10 1.65E-04 5.86E-07 7.58E-06 37 128 "ALDH4A1,C1QC,CLDN10,CDC25B,BTF3L4,CREM,PDE4DIP,DCAF4,DCC,DMD,DNM1L,EGFR,VPS13B,DMTN,SYNCRIP,ANKFY1,CGREF1,MSANTD4,HBS1L,GPR19,ITGA7,LIMS1,ZFYVE27,CPNE9,NAP1L2,P2RX7,SEPT4,C19orf57,PRKAR1B,PBRM1,SCMH1,IGSF9B,MCF2L,WASHC4,ENHO,PORCN,CAB39L" Pubmed 15935055 "Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation." Pubmed 7.59E-10 1.74E-04 6.14E-07 7.93E-06 15 25 "DOC2A,BSN,CALB1,RAB3C,GAP43,GRIN1,SCAMP5,RAB3A,STX1B,SNAP25,STX1A,STXBP1,SYN1,SYN2,SYP" Pubmed 22334647 Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons. Pubmed 7.59E-10 1.74E-04 6.14E-07 7.93E-06 15 25 "LDB2,CDH10,ELAVL3,ELAVL4,TBR1,DKK3,GFAP,L1CAM,PAX6,PTN,FEZF2,RORB,SOX2,SATB2,CUX2" Pubmed 22365546 Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Pubmed 8.34E-10 1.92E-04 6.63E-07 8.57E-06 12 16 "APC,MYRF,ZEB2,OLIG1,OLIG2,GFAP,SMAD1,MBP,PDGFRA,PLP1,SOX10,UGT8" Pubmed 18599437 Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. Pubmed 8.34E-10 1.92E-04 6.63E-07 8.57E-06 12 16 "CDK5R1,ETV1,FABP7,TUBB3,TBR1,GAD1,GAD2,GRIN1,MAP2,MEF2C,NCAM1,SYP" Pubmed 27984743 Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Pubmed 8.34E-10 1.92E-04 6.63E-07 8.57E-06 12 16 "PPFIA2,SYNJ1,SLIT2,DNM2,SHANK1,NBEA,RAPGEF6,SRRM4,VPS13C,ITSN1,ZMYND8,VAV2" Pubmed 24305805 Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. Pubmed 8.34E-10 1.92E-04 6.63E-07 8.57E-06 12 16 "AP2A1,AP2A2,AMPH,SNAP91,PARD6A,CELSR3,EPHB1,L1CAM,MAPK8,MAPK9,CNTN2,FZD3" Pubmed 24948802 Stage-specific regulation of oligodendrocyte development by Wnt/?-catenin signaling. Pubmed 8.34E-10 1.92E-04 6.63E-07 8.57E-06 12 16 "AXIN2,OLIG1,OLIG2,FABP7,GFAP,GLI2,MBP,PDGFRA,PLP1,PTCH1,SOX10,TCF7L2" Pubmed 24997765 Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Pubmed 9.07E-10 2.08E-04 7.19E-07 9.29E-06 19 40 "APC,LDB2,INA,AKAP12,KIF26A,SV2B,EFNB3,EPHB1,TBR1,LRRTM3,MBP,FEZF2,SLC15A2,ERBIN,SATB2,CUX2,TIE1,FLRT2,TMEM163" Pubmed 18371380 Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Pubmed 9.33E-10 2.14E-04 7.31E-07 9.45E-06 14 22 "APC,OLIG2,FABP7,TUBB3,GAP43,GFAP,MAP2,MBP,NEFH,NF1,MAPK3,SOX2,SYN1,SYP" Pubmed 11239428 Tbr1 regulates differentiation of the preplate and layer 6. Pubmed 9.33E-10 2.14E-04 7.31E-07 9.45E-06 14 22 "CDK5R1,CDK5R2,CALB2,CAMK2A,NCAN,ETV1,TUBB3,TBR1,GFAP,MAP2,RELN,CNTN2,VLDLR,LRP8" Pubmed 25875176 Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development. Pubmed 9.33E-10 2.14E-04 7.31E-07 9.45E-06 14 22 "NRP2,BMP7,CCK,CCKBR,ERBB4,ETV1,GAD1,GFAP,CLDN11,RELN,RORB,CNTN2,SATB2,CUX2" Pubmed 25382142 Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle. Pubmed 9.93E-10 2.28E-04 7.73E-07 9.99E-06 13 19 "AQP4,OLIG2,GALC,GFAP,KCNJ10,MBP,NEFH,PDGFRA,PLP1,S100B,MLC1,TJP1,HEPACAM" Pubmed 23303943 Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions. Pubmed 9.93E-10 2.28E-04 7.73E-07 9.99E-06 13 19 "CNTN1,GAP43,GFAP,L1CAM,MAP2,NEUROD2,POU3F2,ROBO1,SOX5,CNTN2,SATB2,CUX2,SLC17A7" Pubmed 23042737 Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Pubmed 1.14E-09 2.62E-04 8.84E-07 1.14E-05 16 29 "AXIN2,BMP7,CALB1,CALB2,SLIT2,FABP7,TUBB3,TBR1,GFAP,L1CAM,NFIA,NFIX,MAPK3,PTCH1,SLC1A3,SATB2" Pubmed 29459677 A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Pubmed 1.22E-09 2.81E-04 9.46E-07 1.22E-05 56 247 "ERMN,BEND6,AMER3,ZBTB10,C5,CAMK2D,HIP1R,DLGAP2,CLTC,MAP4K4,ARMC8,IFFO1,OSBPL3,PHF14,SGSM2,EGFR,TUBD1,RCSD1,AMZ2,TUBA1B,TUBB3,SMC2,ARFIP1,TUBA1C,IL1RAPL1,HSP90AA1,LRRCC1,TUBB2B,SYTL4,AFDN,GIT1,HNRNPM,NUMA1,PLEC,PTPN13,PCMTD2,RYR3,CCDC112,ATXN7,SFPQ,BTBD3,ZFP1,SNRPN,SOX1,SPTAN1,IQCE,ARHGEF12,TEX15,METTL3,TRIO,TUBB2A,UBC,MEAF6,PRDM2,TUBA1A,NUP214" Pubmed 23382219 Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Pubmed 1.50E-09 3.44E-04 1.16E-06 1.49E-05 31 98 "ADCYAP1R1,ADRB2,ALK,APP,DDR1,GPR37L1,TAOK2,SLITRK5,GPR61,EGFR,ERBB2,ERBB4,TLR7,ADGRV1,FGFR1,FLT1,GPR37,GRM7,GPR62,LRP1B,MTTP,NTRK2,NTRK3,OLR1,PTPRB,PTPRN2,RET,TRPC1,VLDLR,LRP8,SNX27" Pubmed 16712791 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Pubmed 1.82E-09 4.19E-04 1.40E-06 1.81E-05 87 466 "SERPINA3,SDE2,ABR,CLK4,ACTN2,NDRG2,OLMALINC,KIAA1324,ALCAM,ASPH,ATP1A3,AZGP1,BCS1L,CFLAR,HAP1,MAP7,CCK,CDH2,PICK1,CHD1L,GALNT9,IP6K1,LYPD1,SUGP2,EGFR,LRRC23,CD320,F5,WAC,BAIAP2,IP6K2,WDR83,APOPT1,SDCBP2,DKK3,GABRB3,MTHFD2,ARFIP1,GJB1,AGBL5,HP,HPR,ZIC5,ITIH2,STXBP5,ZFYVE27,MBP,BLOC1S2,MT3,MTTP,MX1,MYO9A,IDNK,NME4,PDE1C,ABCB1,TATDN3,PRKAB2,CEP41,PRKCZ,MASP1,WBP1L,TUG1,RGS10,TMEM100,RPL38,RPS20,MAPK12,SELL,COPZ1,FUZ,CLSTN1,KANSL3,EPC1,DMRTC1,SPP1,DBNDD2,PBLD,ADHFE1,MLC1,PRRC2C,SYN2,SLC35G2,C9orf85,DNAJC12,POLR3H,ZNF189" Pubmed 21228161 Calcium channels link the muscle-derived synapse organizer laminin ?2 to Bassoon and CAST/Erc2 to organize presynaptic active zones. Pubmed 1.90E-09 4.37E-04 1.46E-06 1.88E-05 11 14 "BSN,CACNA1A,CACNA1B,ERC2,SV2B,SV2A,PCLO,NEFH,ERC1,SYN1,SYP" Pubmed 20634891 Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Pubmed 1.94E-09 4.45E-04 1.48E-06 1.91E-05 68 331 "ACTN1,C1QTNF3,AMT,APOC2,MARK4,PTCH2,BMPR1B,CBS,CDH2,FOXN3,CHRNA4,NRXN2,NIPBL,COL11A2,NECTIN3,CTH,ZEB2,ARNT2,DLX1,EDN1,EGFR,EGR3,EMX2,ERCC2,PIPOX,EYA1,FGF1,FGF12,FGFR1,FGFR3,FOXF2,FOLH1,FOLR2,POMT1,CHL1,GABRB3,GAD1,GAD2,SALL3,MTHFD2,GART,ALDH1L1,GDF1,GLI2,NR3C1,HSP90AA1,SMAD1,MAT2A,MTR,OGG1,PDGFRA,ABCB1,PRRX1,PTCH1,RET,RXRG,SALL1,SOX1,SOX5,SPP1,TBX15,SATB2,CUX2,LEFTY2,TGFBR3,TRPS1,NSD2,ZNF189" Pubmed 19521500 The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Pubmed 2.15E-09 4.94E-04 1.64E-06 2.11E-05 53 231 "ABAT,ADD2,OGT,ADGRB3,DDX46,KLHL5,ING4,ETV1,RTN3,TUBB3,FGFR1,SORBS1,TBR1,GAB1,NCKAP1,GAP43,SESN1,CBX1,PCSK1N,IDH3A,LIX1,MEST,KCTD6,NELL2,NEUROD1,NFYA,NTRK2,IGSF11,OGDH,PAK3,PAX6,ENPP2,GPR85,FAM98B,PKM,PEX2,RAB3A,RDX,ELP2,RPS20,PUF60,NTNG1,BCAN,KBTBD4,SCN3B,BEX1,NCDN,ZC3H4,TAF9,TBL1X,MTMR14,UBTF,PLPPR2" Pubmed 27452460 The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Pubmed 2.17E-09 4.98E-04 1.65E-06 2.13E-05 14 23 "ADORA2A,ASCL1,CALB2,CHRM4,DRD1,EBF1,GRIK3,NPY,NTRK2,P2RY1,PDYN,PENK,SST,TAC1" Pubmed 15939374 eXPRESSION: an in silico tool to predict patterns of gene expression. Pubmed 2.22E-09 5.10E-04 1.68E-06 2.17E-05 16 30 "DGKD,ASGR1,CADM3,SYNGR3,OLIG1,DYNC1I1,OLIG2,B3GAT1,TBR1,IGFBPL1,NAP1L2,PCSK2,MYT1L,SEZ6L,TTPA,FRRS1L" Pubmed 12853948 The DNA sequence of human chromosome 7. Pubmed 2.26E-09 5.19E-04 1.70E-06 2.20E-05 87 468 "ACHE,FZD9,AMPH,CDK13,AZGP1,SGCE,FOXK1,CACNA2D1,CAMK2B,KRIT1,CHN2,KMT2C,SUMF2,CREB5,OSBPL3,CNTNAP2,PLXNA4,FAM131B,DOCK4,HDAC9,DGKB,SCRN1,MAGI2,GSDME,POM121,CALN1,DYNC1I1,DPP6,DNAJB6,FIS1,SEMA3D,EGFR,RASA4,AASS,ELN,STARD3NL,EN2,LRRC17,ETV1,ACTL6B,PRKAG2,MPP6,DBF4,GPR22,GPR37,PCLO,GRB10,GRM3,HTR5A,IGFBP1,SCIN,KCND2,KCNH2,ADAM22,NDUFA5,NPY,NPTX2,NRCAM,PDE1C,GPR85,CDK14,ABCB1,PHKG1,ZNF655,SNX10,PMS2,ING3,NXPH1,RELN,SAMD9,SUGCT,PPP1R9A,RADIL,SMARCD3,SP4,PEG10,SRPK2,NACAD,STX1A,KLHL7,SYPL1,ZKSCAN5,UBE2H,CLIP2,LAT2,ST7,ACTR3B" Pubmed 26460568 Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. Pubmed 2.33E-09 5.36E-04 1.75E-06 2.26E-05 46 187 "RBM10,MAP4K3,APBB2,DST,INA,ARHGEF1,RTTN,DMD,CELSR3,TUBA1B,TUBB3,TUBB4A,RACK1,PRMT5,TUBA8,SPIN1,HSPA1L,HSP90AA1,TUBB2B,KIFC3,HNRNPM,NEFM,NEFH,DNHD1,SEMA5B,PKD1,PLEC,PRPH,MYH14,MYO18A,ANKRD36,SNRPN,KIF21B,ZC3H13,SPTAN1,SPTB,PHLDB1,SYNE2,PLCB1,CLASP1,SYNE1,ARHGEF12,WIPF1,TUBA1A,DNAH10,GAN" Pubmed 21244100 Protein array based interactome analysis of amyloid-? indicates an inhibition of protein translation. Pubmed 2.37E-09 5.45E-04 1.78E-06 2.29E-05 64 305 "ABCF1,PDZD4,GPAM,PHYHD1,APP,TRIM41,SYT6,USP2,TBPL1,PNKD,CSNK1E,SOCS5,CTNND1,USP6NL,HDAC4,HP1BP3,ALKBH8,PARD6A,TRAPPC9,DNM2,FCF1,EEF1D,EPB41L2,CDKL3,FGF12,FGF13,SYNCRIP,SGIP1,ZCCHC17,CAMKK2,GABRA4,GLRB,AIFM3,POLL,LNX1,PSRC1,KIF3A,KLF12,ZNF385B,KCNN3,ADAM22,OPA1,PURG,MAPK7,GRAMD1C,GTDC1,RFX5,TTLL7,MRPS18A,CARF,ST6GALNAC6,ATAT1,TRIM46,ZNF365,TMCC1,RBM34,TAB2,ROBO3,TAF6,THBS4,NSD2,KLC2,UPF3A,KCNAB1" Pubmed 12690205 Human chromosome 7: DNA sequence and biology. Pubmed 2.57E-09 5.89E-04 1.86E-06 2.40E-05 96 536 "ATP6V0E2-AS1,ACHE,ADCYAP1R1,ESYT2,AMPH,AZGP1,GPR146,CASTOR3,JAZF1,GPC2,CAMK2B,VSTM2A,ISPD,KRIT1,DGKI,AP4M1,TBRG4,ASIC3,CHN2,C7orf61,CREB5,OSBPL3,CNTNAP2,PLXNA4,PNPLA8,DGKB,KIAA0087,ELMO1,MAGI2,TMEM130,NYAP1,CALN1,DYNC1I1,DNAJB6,SEMA3D,AASS,LINC-PINT,STARD3NL,EN2,ETV1,ACTL6B,PRKAG2,AGAP3,SLC37A3,TPK1,MPP6,GCK,GPR22,GPER1,GPR37,PCLO,GRM3,HTR5A,IGFBP1,KCND2,KCNH2,MEST,MKLN1,COL28A1,DBNL,NPY,NPTX2,CDK14,ABCB1,ZNF655,SNX10,PILRA,NXPH1,CEP41,EPDR1,RELN,SAMD9,PTN,PTPRZ1,GAL3ST4,ZDHHC4,SUGCT,PPP1R9A,SMARCD3,HECW1,LRRC4,SYPL1,TAC1,TAF6,TMEM178B,GALNT17,RUNDC3B,ZKSCAN5,UBE2H,LINC00689,CCDC136,VIPR2,AGMO,AMZ1,ST7,PRRT4" Pubmed 26659141 Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Pubmed 2.58E-09 5.93E-04 1.86E-06 2.40E-05 13 20 "UNC5A,CALB2,DCC,DSCAM,EBF1,TBR1,L1CAM,MAP2,POU3F2,DRAXIN,NTNG1,UNC5B,CNTN2" Pubmed 20696379 Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Pubmed 2.58E-09 5.93E-04 1.86E-06 2.40E-05 13 20 "SLIT2,LHX2,DCC,ETV1,TUBB3,MSI1,PAX6,ROBO1,ROBO2,SLIT1,ROBO3,CNTN2,SLC17A6" Pubmed 26182416 Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Pubmed 2.58E-09 5.93E-04 1.86E-06 2.40E-05 13 20 "ELAVL3,ELAVL4,OLIG2,TUBB3,TBR1,GFAP,L1CAM,NEUROD1,PAX6,POU3F2,UNC5D,SATB2,ZFPM2" Pubmed 23332759 Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "APC,MYRF,OLIG1,OLIG2,GFAP,MBP,PDGFRA,PLP1,SALL1,SMARCA4,SOX10,UGT8" Pubmed 12533617 DLX5 regulates development of peripheral and central components of the olfactory system. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "DLX1,TUBB3,TBR1,GAD1,GAD2,GAP43,HES5,NCAM1,NCAM2,NPY,PAX6,RELN" Pubmed 21068328 Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "PRX,ADAM23,ELAVL3,ELAVL4,FABP7,TUBB3,GFAP,ADAM11,ADAM22,PRPH,SOX10,LGI4" Pubmed 17376983 Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "ASCL1,SLC32A1,DLX1,ERBB4,ETV1,GAD1,HES5,PAX6,RELN,ROBO1,ROBO2,SLIT1" Pubmed 17721516 OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "PCDH10,ASCL1,NRP2,CALB2,EBF1,EMX2,PPP1R1B,L1CAM,PAX6,NTNG1,SLIT1,CNTN2" Pubmed 25568100 Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "MYRF,OLIG2,GFAP,GLUL,IFI16,MBP,NKX2-2,PDGFRA,PLP1,SLC1A3,SMARCA4,SOX10" Pubmed 16715082 Midline radial glia translocation and corpus callosum formation require FGF signaling. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "CALB2,CDH2,SLIT2,DCC,FABP7,TUBB3,FGFR1,GAP43,GFAP,L1CAM,ROBO1,CNTN2" Pubmed 22542597 The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Pubmed 2.58E-09 5.94E-04 1.86E-06 2.40E-05 12 17 "APC,CSF1,CSF1R,TUBB3,TBR1,GFAP,MBP,PAX6,PDGFRA,S100B,SATB2,IL34" Pubmed 18579678 Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Pubmed 2.66E-09 6.12E-04 1.91E-06 2.47E-05 18 38 "ASCL1,NOG,LHX2,ETV1,TUBB3,FOXG1,GRIK4,RBPJ,HES5,KITLG,PROX1,RELN,ROBO1,RORB,SLIT1,CUX2,HEY1,HEY2" Pubmed 12787561 Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR). Pubmed 2.93E-09 6.72E-04 2.09E-06 2.71E-05 23 60 "ABR,PLEKHG5,FGD2,KALRN,ARHGEF2,NGEF,ARHGEF6,MAGED1,ARHGEF4,TIAM2,APH1A,MAPK8,RASGRF1,RASGRF2,ITSN1,FGD4,ARHGEF9,ARHGEF12,ITGB3BP,TIAM1,UBC,VAV1,VAV2" Pubmed 27611684 mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium. Pubmed 3.34E-09 7.67E-04 2.38E-06 3.08E-05 15 27 "DPF1,ASCL1,LHX2,ELAVL3,ELAVL4,TUBB3,ACTL6B,FOXG1,GAP43,NCAM1,NEUROD1,PAX6,RELN,SMARCC2,SOX2" Pubmed 27568519 Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Pubmed 3.74E-09 8.59E-04 2.66E-06 3.44E-05 22 56 "CPNE5,LDB2,CDH8,CDH10,CREB5,TMTC1,OLIG2,EPHA5,MEGF11,DKK3,NKX6-2,ARHGAP36,HLF,CDH20,LIFR,SMAD1,SMAD9,NOS1,PAX6,PBX1,SOX5,CDH22" Pubmed 16723544 WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. Pubmed 3.92E-09 9.01E-04 2.76E-06 3.56E-05 10 12 "CNTNAP1,APC,WASF1,OLIG2,WASF3,KCNA1,MBP,SCN2A,SCN8A,NFASC" Pubmed 25285789 "Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor." Pubmed 3.92E-09 9.01E-04 2.76E-06 3.56E-05 10 12 "OLIG2,FABP7,FGFR3,GFAP,GLUL,RELN,S100B,SLC1A3,SLIT1,SOX10" Pubmed 28283561 Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness. Pubmed 3.92E-09 9.01E-04 2.76E-06 3.56E-05 10 12 "TBR1,DISC1,KCNA1,KCNA2,KCNA6,KCNB1,L1CAM,PDE4A,PDE4B,SCN8A" Pubmed 15457507 Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. Pubmed 3.92E-09 9.01E-04 2.76E-06 3.56E-05 10 12 "NRP2,DCC,ERBB4,TUBB3,GAP43,L1CAM,NCAM2,ROBO2,NTNG1,CNTN2" Pubmed 17883393 Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains. Pubmed 4.17E-09 9.59E-04 2.92E-06 3.78E-05 16 31 "ST3GAL5,B4GALT6,GAL3ST1,ST8SIA3,FUT9,B3GAT1,GALC,B4GALNT1,NEU3,MAP2,ST8SIA5,ST6GALNAC6,ST8SIA1,SOX2,NEU4,UGT8" Pubmed 22906231 Neurog1 and Neurog2 coordinately regulate development of the olfactory system. Pubmed 4.54E-09 1.04E-03 3.17E-06 4.10E-05 17 35 "ASCL1,CALB2,DLX1,ETV1,TBR1,GAD1,GAP43,STMN2,NCAM1,NEUROD1,NTRK2,NTRK3,PAX6,RELN,S100B,SLC17A7,SLC17A6" Pubmed 24711643 Identifying biological pathways that underlie primordial short stature using network analysis. Pubmed 4.59E-09 1.06E-03 3.20E-06 4.13E-05 157 1024 "ABCF1,ACLY,RBM10,ACTN1,ADAR,AP2A1,EP400,APP,ARHGDIA,CCAR2,ATP1A1,ATP2A2,ATP2B1,DST,FUBP1,CACNA2D1,CANX,CBR1,INA,AIFM1,ARHGEF2,LRWD1,SRSF11,SLIT2,MYL6B,CLTA,CLTC,TJP2,MAP4K4,NIPBL,RBM39,CS,SEC24C,CTNND1,PUM1,GAPVD1,MATR3,INTS1,MYEF2,HP1BP3,CEP170,ZC3H11A,DDX46,POM121,SACS,SEC16A,PDCD6IP,EDIL3,EEF1D,SUGP2,EIF4G1,EPB41L2,SRRM1,F5,TUBA1B,RACK1,PRMT5,ATP5PD,SYNCRIP,FLNC,NOP56,SMC2,SPECC1,FYN,NEURL4,STAG2,SEPT9,GART,SRCAP,RNPS1,ZNF638,CBX1,GNAS,GOLGB1,GPD2,NUDT21,TUBA1C,CIT,GSN,PSIP1,HBA1,HNRNPK,IDH3A,IDH3B,DOCK7,SCIN,TUBB2B,KIF2A,IPO5,MAP4,AFDN,MYO5A,NACA,NAP1L1,NF1,NUMA1,PCMT1,OLA1,PFKP,ABCB1,PKM,NLE1,PLEC,EXOSC10,PEX5,RAB5B,KIF7,PBRM1,MYH14,EXD2,RPL15,ZC3H14,NCBP3,SAFB,SFPQ,TRA2B,PUF60,PPP1R9A,SHMT2,DHX30,SLC12A2,SMARCA4,SMARCC2,SON,EMC1,MYCBP2,ITPRID2,NCDN,STAU1,PHLDB1,GANAB,ZC3H4,SUPT5H,SYNE2,SYNE1,OBSL1,DICER1,TJP1,CBX5,TMPO,TPM3,UBC,RPL7L1,AMOT,UBTF,UCHL1,TBC1D15,XPO1,SF1,ZNF24,FIP1L1,ITM2C,HNRNPA3,NUP214,AAAS,FXR1,LAS1L" Pubmed 24698270 "Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity." Pubmed 4.74E-09 1.09E-03 3.29E-06 4.25E-05 14 24 "PCDHGC3,PCDHGB7,PCDHGB2,PCDHGA10,PCDHGA3,PCDHB15,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 10574461 Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. Pubmed 4.79E-09 1.10E-03 3.32E-06 4.29E-05 26 76 "GALNT16,DSCAML1,TMCC3,HHATL,SLC12A5,PNMA8B,ERMN,GPR158,CADPS,CACNA1I,CACNA1G,HECTD1,PNKD,CDC42BPB,KLHL3,SRGAP3,NXPH3,CCSER2,MINDY2,SCN3B,ZC4H2,ZMYND8,NDRG4,SPIRE1,SMARCAD1,TTC7A" Pubmed 23376485 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Pubmed 5.14E-09 1.18E-03 3.55E-06 4.58E-05 242 1744 "SERPINA3,ABAT,ACADM,ABHD6,ACTN2,SLC25A25,NDRG2,GALNT16,AGT,TAOK1,ALAD,SPARCL1,BBOX1,LTBP4,PI16,ANXA7,APOC1,APOC2,APP,PDXK,ARHGDIA,ARSF,ASPA,DYNLL1,ATP1A1,SLC4A4,ALDH7A1,ATP6V0A1,AZGP1,BCL2L2,BID,PROM1,DST,C1QC,RAB29,CA4,DDR1,CACNA2D1,CALB1,THSD7A,CALM1,CANX,SPAG9,CBR1,ENTPD6,CD81,CDC42,CDH2,ZNF445,ADGRG1,SLIT2,SLC22A6,PPT2,CLU,TPP1,CLTC,CNTN1,COX4I1,CP,GDA,CRYM,CS,CSF1,CST3,ZSCAN23,MYADM,ACY3,IST1,DBI,AIF1L,B3GAT3,DPP6,PDCD6IP,SNX29,SH3GLB1,GOLGA7,COPS4,PCOLCE2,EPB41L2,ENPP6,STX2,EPS8,NCALD,RTN3,SIRPB1,EXTL2,CD320,F3,REEP2,ACSL4,TUBA1B,EFEMP1,RACK1,ST3GAL6,FCGR3A,BAIAP2,ATP5PD,PCYOX1,UFM1,FAM49B,ATP6V1H,TPPP3,SDCBP2,GAA,CAB39,AHCYL1,GALC,IQGAP2,GATM,ALDH1L1,LYVE1,DHRS4,GK,COPS8,GLUL,PCDH11X,PCSK1N,GNAS,LILRB4,GPD1,GRM5,BTN2A1,GSN,KIF3A,GYG1,HBA1,PACSIN2,VSIG4,ZDHHC15,HP,NEGR1,HSP90AA1,GAREM2,SCIN,IL6ST,ITGAM,ITGAV,KCNMA1,KHK,LAMA2,LAMP2,GPR155,MAOB,MAP4,LYPLAL1,MSRA,MYO6,NACA,BEX5,NCAM1,DDR2,IGSF11,OCRL,OLR1,OPCML,CLDN11,PAH,PCDHGC3,PCMT1,GNG2,OLA1,ABCB1,SERPINI1,A2ML1,PKM,PLCD1,PLEC,TRHDE,PSAT1,POLG,PTPA,PPP3CC,PRKACB,MAPK3,EPDR1,PSMA6,PSMD13,PTH1R,PTPN13,PTPRG,PTPRO,RIPOR1,QDPR,FAT4,RNASE1,RNH1,MYH14,KIRREL1,CCDC25,EPHA10,RPL15,UEVLD,PTGR2,RPS20,HOGA1,SCP2,MRAS,KIF27,SH3GL2,SH3GL3,FRMPD1,ST6GAL1,CLSTN1,SLC2A5,EFHD1,SPHKAP,CDK5RAP2,SPP1,NFASC,PBLD,APOM,GANAB,PLCB1,SYPL1,TAC3,PDLIM2,MGRN1,PCDHGC5,CLASP1,SZT2,TF,TGFBR3,TST,UBC,CADM1,UCHL1,PITPNB,FLRT2,TOM1L2,TBC1D15,ZNF711,ELFN1,CRB2,RGMA,SEMA3B,PCDH15,URM1,CAB39L,ITM2C,MVB12B,PLSCR4,RTN4" Pubmed 18973680 Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Pubmed 5.48E-09 1.26E-03 3.77E-06 4.87E-05 59 277 "KDM5D,PCDH19,AMPH,ANK3,APP,CDC14B,ASTN1,ATM,SLC4A4,BCL2L2,PROM1,INA,IGDCC3,HAPLN1,GPSM1,DBT,MYEF2,FAM107B,CD99L2,PLEKHA1,AMZ2,FABP7,TUBB4A,SCARA3,ILDR2,PCSK1N,AP4S1,RABL2A,CFAP126,INPP1,FGFBP3,MEST,KITLG,SESN3,PTOV1,NNAT,NPTX2,PCSK5,PPP1R1A,PTPRG,SLC25A36,SCN2B,SFPQ,SCG5,EFHD1,LIMCH1,TROVE2,SMOC1,PHLDB1,ZC3H4,PDLIM2,TIE1,TRH,CADM1,RPL7L1,FLRT2,TBC1D15,ZBTB16,MAP3K12" Pubmed 23948231 Sox2 modulates the function of two distinct cell lineages in mouse skin. Pubmed 6.18E-09 1.42E-03 4.21E-06 5.44E-05 13 21 "PROM1,CACNA1A,RAB3C,DCC,PCLO,NCAM1,NEFH,PDGFRA,SOX2,SOX10,SYN2,UCHL1,SLC17A6" Pubmed 19657336 SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development. Pubmed 6.18E-09 1.42E-03 4.21E-06 5.44E-05 13 21 "ASCL1,CALB1,CALB2,OLIG2,TBR1,NPY,PAX6,RELN,SOX6,SOX5,SST,CUX2,SLC17A6" Pubmed 17084361 SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Pubmed 6.18E-09 1.42E-03 4.21E-06 5.44E-05 13 21 "OLIG2,FABP7,GLUL,SOX21,MBP,PDGFRA,PLP1,SOX8,SOX6,SOX3,SOX5,SOX10,SOX11" Pubmed 27503909 Gsk3? and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease. Pubmed 6.31E-09 1.45E-03 4.29E-06 5.54E-05 85 463 "ASPHD1,MTUS1,GPAM,CDK10,ASPH,NUMB,ATP1A1,AIFM1,LRRFIP1,CLTC,FBXO7,QKI,LETMD1,MAGED1,TBPL1,RBM39,CLIP3,CSNK1E,MATR3,TOMM20,ACOT8,DNAJB6,USH1C,EEF1D,EIF4G1,PLEKHA1,SRPK3,ERBB2,TUBB4A,RACK1,GORAB,FGF13,FGFR1,AMOTL2,C2orf88,AK8,KHDRBS3,INPP5K,PRRC2B,ANKRD36BP1,HNRNPK,HSP90AA1,KIFC3,KPNA5,PACRG,MARK3,MBNL1,MEST,MITF,HNRNPM,SFR1,NFIA,PDE4D,TMOD2,CDK14,ZFYVE21,XRN1,PKM,PRKACB,PRKCB,PRKCG,MAPK9,MAPK10,PSMA6,RET,RORB,RPS20,ATAT1,S100B,PUF60,SHMT2,CPEB4,SNAP25,MBD5,CMTR2,SON,INKA2,TMPRSS5,TUBB2A,CLHC1,AMOT,SLAIN1,TMEM237,KCNAB1,IFT88" Pubmed 12490199 Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "OLIG2,TUBB3,GFAP,MAP2,MBP,NKX2-2,PAX6,PDGFRA,PLP1,S100B,SOX10" Pubmed 17482548 LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "BRSK2,TUBB3,STRADA,TBR1,BRSK1,CAB39,L1CAM,MAP2,MAPT,RELN,CNTN2" Pubmed 22956844 Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "ASCL1,FABP7,TUBB3,TBR1,GFAP,SOX21,HES5,NCAM1,POU3F2,S100B,SOX2" Pubmed 23064108 Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "CALB1,CALB2,CCK,SLC32A1,GAP43,NPY,STX1B,SNAP25,STX1A,SLC17A7,SLC17A6" Pubmed 24257626 Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "MYRF,OLIG2,GFAP,GLUL,MBP,PDGFRA,PLP1,SOX1,SOX2,SOX3,SOX10" Pubmed 9481670 Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+. Pubmed 6.50E-09 1.49E-03 4.34E-06 5.61E-05 11 15 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIA1,GRIA2,GRIA4,GRIN1,GRIN2D" Pubmed 21220101 Specific functions for ERK/MAPK signaling during PNS development. Pubmed 6.55E-09 1.50E-03 4.36E-06 5.63E-05 15 28 "APC,OLIG2,ERBB2,ETV1,FABP7,MAG,MBP,NEFH,PDGFRA,MAPK3,MAPK7,RPS6KA2,S100B,SOX2,UCHL1" Pubmed 18455991 Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Pubmed 6.76E-09 1.55E-03 4.44E-06 5.73E-05 9 10 "OLIG1,OLIG2,NKX6-2,GFAP,NFIA,NKX2-2,PAX6,RELN,SLIT1" Pubmed 27067865 Brg1 directly regulates Olig2 transcription and is required for oligodendrocyte progenitor cell specification. Pubmed 6.76E-09 1.55E-03 4.44E-06 5.73E-05 9 10 "ELAVL4,OLIG2,FABP7,TBR1,MAP2,PAX6,PDGFRA,SLC1A3,SMARCA4" Pubmed 21789198 Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. Pubmed 6.76E-09 1.55E-03 4.44E-06 5.73E-05 9 10 "ASIC2,ASIC1,ASIC3,GABRA1,GABRA2,GABRA3,GABRA4,GABRG1,GABRG2" Pubmed 11804571 Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Pubmed 6.76E-09 1.55E-03 4.44E-06 5.73E-05 9 10 "CALB1,CALB2,SLIT2,GFAP,NEFH,NPY,ROBO1,ROBO2,SLIT1" Pubmed 26525805 Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. Pubmed 6.76E-09 1.55E-03 4.44E-06 5.73E-05 9 10 "MYRF,OLIG2,GLUL,MBP,PDGFRA,SOX6,SOX2,SOX5,SOX10" Pubmed 23535033 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Pubmed 7.03E-09 1.62E-03 4.56E-06 5.89E-05 21 53 "ARHGAP20,VAT1L,CACNA1G,SLC4A8,ST18,ELMO1,MRPL10,MEGF10,AFF1,MOBP,BCAS3,STK32B,LIMS2,MYO16,HECW1,NKAIN2,PRRC2C,ANO4,CSMD1,FMN2,PLPP4" Pubmed 18985723 GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Pubmed 7.06E-09 1.62E-03 4.56E-06 5.89E-05 12 18 "SLC32A1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRB1,GABRB3,GABRG1,GABRG2,SLC6A1,SLC6A11" Pubmed 12799088 Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Pubmed 7.06E-09 1.62E-03 4.56E-06 5.89E-05 12 18 "PLEKHG5,ARHGEF7,ARHGEF25,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF10L,MCF2L,DNMBP,ARHGEF12,SPATA13" Pubmed 18311135 Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. Pubmed 7.06E-09 1.62E-03 4.56E-06 5.89E-05 12 18 "CAMK2A,CAMK2B,CAMK2D,CAMK2G,AKAP5,DLG4,CACNG2,GRIA1,GRIA2,GRIA4,MYO5A,MYO6" Pubmed 26701169 "Prss56, a novel marker of adult neurogenesis in the mouse brain." Pubmed 7.06E-09 1.62E-03 4.56E-06 5.89E-05 12 18 "APC,CALB1,CALB2,ELAVL3,ELAVL4,FABP7,TUBB3,GFAP,NEUROD1,PROX1,SOX2,SOX10" Pubmed 25331604 NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Pubmed 7.06E-09 1.62E-03 4.56E-06 5.89E-05 12 18 "ASCL1,CALB1,CALB2,TUBB3,GAD1,GFAP,HES5,NCAM1,NFIX,PAX6,S100B,SOX2" Pubmed 16516881 Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening. Pubmed 7.59E-09 1.74E-03 4.87E-06 6.30E-05 16 32 "RUNX1T1,ZEB2,SALL3,IGFBPL1,KIT,PRKCG,ROBO2,RORB,SATB1,C11orf87,AJAP1,TCF4,PRMT8,TRPC3,FRRS1L,NETO2" Pubmed 22991445 Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Pubmed 7.59E-09 1.74E-03 4.87E-06 6.30E-05 16 32 "AQP4,EMX2,TUBB3,TBR1,ALDH1L1,GFAP,KIRREL3,PAX6,POU3F2,FEZF2,CRTAC1,RORB,SLC14A1,TAC1,SATB2,CUX2" Pubmed 16751776 A germline-specific class of small RNAs binds mammalian Piwi proteins. Pubmed 7.88E-09 1.81E-03 5.04E-06 6.52E-05 82 443 "ACLY,ELFN2,ARHGAP20,MTMR3,BSN,BRSK2,CARS,HIP1R,USP6,CDC42,LRWD1,COL9A1,COL9A3,AKAP12,SEC24C,APPL1,IP6K1,FBXO25,SV2B,SEC16A,EXOG,RPS6KL1,DNM2,EIF4G2,TNK2,BSCL2,DNAJC27,PTK2B,ATP5PD,WDR83,SPECC1,STAMBP,DOT1L,NEU3,RNPS1,PRRC2B,C1orf94,DDX19B,FAM95B1,ZNF546,KNDC1,MBD1,LOC643201,XRRA1,NUMA1,FAM225B,PDPK1,CDIP1,POLG,PTPA,PEX5,PLEKHB2,RAD51D,ZDHHC4,RGS12,RPS6KA2,SBF1,CCDC92,CCDC88A,IFT122,SON,WDTC1,ZHX3,SPTB,CDK19,MPRIP,TTBK2,MLC1,SYN2,ANKRD12,USP22,CBX5,WBP2,NR2C2,CCDC136,TOM1L2,CSDE1,WIPF2,MARCH8,UBE3B,RNF170,IFT88" Pubmed 20935630 "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Pubmed 8.10E-09 1.86E-03 5.16E-06 6.66E-05 22 58 "ZNF608,CCDC146,STK33,PTBP2,NRXN3,IQCK,SH2B1,DNAJC27,CELF1,CBX1,ATXN2L,HMGCR,HNF4G,NEGR1,LRP1B,KCTD15,FTO,SKOR1,FAIM2,ZC3H4,TUB,CADM2" Pubmed 19734545 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. Pubmed 8.10E-09 1.86E-03 5.16E-06 6.66E-05 22 58 "API5,JAM2,NRXN1,SLC24A2,NCOR2,TOX,CORO2B,FLT1,GABRB3,ARPP21,LMO2,MDM4,MID1,MOBP,FAT4,RIT2,SEC14L1,SH3GL2,PLCB1,UCHL1,LOC100506497,VANGL2" Pubmed 19125103 "Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia." Pubmed 8.57E-09 1.97E-03 5.39E-06 6.97E-05 8 8 "GAD2,GLUL,GRIA4,GRIK3,GRIK4,GRIK5,GRIN2D,GRM3" Pubmed 23652595 Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice. Pubmed 8.57E-09 1.97E-03 5.39E-06 6.97E-05 8 8 "ATP1A1,ATP1A2,ATP1A3,SLC32A1,GAD1,GAD2,SLC17A7,SLC17A6" Pubmed 17392456 Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. Pubmed 8.57E-09 1.97E-03 5.39E-06 6.97E-05 8 8 "CALB1,CALB2,SLIT2,L1CAM,NPY,ROBO1,ROBO2,SLIT1" Pubmed 11879655 Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Pubmed 8.57E-09 1.97E-03 5.39E-06 6.97E-05 8 8 "AP2A1,AP2A2,AMPH,BIN1,SYNJ1,CLTC,DNM1,SYP" Pubmed 20471030 Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Pubmed 8.71E-09 2.00E-03 5.45E-06 7.05E-05 20 49 "SYN3,ANK2,CBR1,FHL5,GDA,CRYM,EPB41L1,GFAP,GLUL,MAPT,MBP,MOG,NEFM,PCMT1,PLEC,PRKCG,QDPR,STX1A,STXBP1,SYT5" Pubmed 19019082 Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. Pubmed 8.71E-09 2.00E-03 5.45E-06 7.05E-05 20 49 "ACLY,APP,CASK,MARK4,ATP1A1,ATP2A2,CBS,TJP2,CRMP1,SCRN1,TMCC2,DCTN2,AHCYL1,GFAP,BRINP3,MAT2A,MEST,ZNF302,STXBP1,TUBB2A" Pubmed 22922362 Transcription factor Foxp3 and its protein partners form a complex regulatory network. Pubmed 9.77E-09 2.24E-03 6.10E-06 7.88E-05 70 358 "ARID1A,ADAR,ADD1,ADD3,AP2A1,AP1B1,CCAR2,ATM,EIF4G3,BCL7A,CAMK2D,KRIT1,ARHGEF1,COPB2,QKI,CNN3,ARHGEF6,AHCTF1,CHD1L,SEC24C,SIPA1L1,GIT2,DBT,ELMSAN1,MYEF2,DNM2,PDCD6IP,DNAJB6,DNM1L,PHC2,EIF4G1,WAC,ACSL4,RGPD5,SPECC1,ARFGAP2,ZNF512,FYB1,RNPS1,ZNF638,TUBA1C,NR3C1,GSN,NCKAP1L,MSL1,LIMS1,MAP4,MBNL1,DBNL,PC,PFKFB3,FAM98B,PLEC,DPF2,NCBP3,ATXN2,DHX30,SMARCA4,SMARCC2,SMARCE1,RBM34,SP2,CLASP2,ZNF346,VAV1,NSD2,TFIP11,INTS3,NUP214,LAS1L" Pubmed 22266860 Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells. Pubmed 1.05E-08 2.40E-03 6.50E-06 8.40E-05 21 54 "MYH7B,CALM1,MYL6B,CDC42BPB,FGFR1OP2,DBN1,TUBA1B,TUBB3,TUBB4A,FHL1,MYL3,MYO6,ODF2,PLEC,PTPA,CNTLN,MYH14,TPM1,TPM2,TPM3,TPM4" Pubmed 24529757 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. Pubmed 1.05E-08 2.41E-03 6.50E-06 8.40E-05 28 89 "ASIC2,TMEM132B,SLITRK1,KCTD16,ALCAM,ANK3,ATP2B2,BMPR1B,NOG,ABCG1,RGS6,CTNND2,CALN1,TMEM132E,EPB41,KCNMB2,ERBB4,STON1,METTL21A,LAMA2,OPCML,PFKP,FAT3,MASP1,MRAS,NFASC,GSE1,SYNPO2" Pubmed 19409883 The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Pubmed 1.23E-08 2.84E-03 7.64E-06 9.88E-05 15 29 "ETV1,TUBB3,TBR1,GRIK4,HES5,MAP2,NEUROD1,PAX6,PROX1,RELN,RORB,SNCB,SNCA,UNC5D,NR2E1" Pubmed 20889312 A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. Pubmed 1.25E-08 2.87E-03 7.72E-06 9.97E-05 23 64 "NCKAP5,MRTFA,VAT1L,BCAS1,CACNA2D1,MYOM2,CRYBB1,CNTNAP2,CTNND2,NTM,DMD,ATP8A2,ADAMTS6,CELF5,DIPK1A,COL28A1,NALCN,VPS13C,RFX2,FAM81A,KDM4C,ASTN2,SMARCAD1" Pubmed 19953087 Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. Pubmed 1.25E-08 2.88E-03 7.73E-06 9.98E-05 47 203 "ERMN,AMPD2,KCNAB2,SHTN1,MARK4,RASL11B,BMPR1B,CDK5R1,BTK,DIRAS1,TRIM41,KCNAB3,TCEAL2,DAPK3,TOM1,SGK2,EGFR,EIF5,DMTN,EPHA5,NSRP1,FGF12,FGFR1,BAIAP2,FLT1,CAMKK2,FYN,SEPT9,GRK4,MAP4K5,KCNB1,KIFC3,MAP2,NTRK2,PDGFRA,PKN2,PRRT2,RGS3,TCP11L1,MAPK12,SGK1,SAMSN1,SYT1,ROBO3,WBP2,TOM1L2,KCNAB1" Pubmed 14676191 Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. Pubmed 1.28E-08 2.93E-03 7.84E-06 1.01E-04 24 69 "MARK4,CCAR2,ARHGEF2,CDC42,BRINP1,PARD6A,STRADA,PNMA2,CAB39,RASSF8,HSP90AA1,DOCK7,LIMS1,MARK1,MARK3,PNMA3,PRKCG,PRKCZ,PNMA8A,MYO18A,CCDC88A,SMARCA4,MTCL1,PARD3" Pubmed 24769233 Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset. Pubmed 1.32E-08 3.03E-03 8.09E-06 1.05E-04 20 50 "ATP1A1,ATP1A2,ATP1A3,ATP2B3,CBR1,CLTC,PDCD6IP,EDIL3,F5,GPM6A,GRIA4,MAN1B1,PCMT1,SERPINE2,PKM,RAB3A,SLC12A2,SPTAN1,TUBB2A,SLC39A12" Pubmed 28069946 Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Pubmed 1.34E-08 3.08E-03 8.19E-06 1.06E-04 16 33 "AXIN2,CAMK2A,CAMK2B,DLG4,GRIA1,GRIA2,GRIN1,MAP2,NEFH,NEUROD1,MAPK3,MAPK8,SYN1,SYP,WNT7A,SLC17A7" Pubmed 17537790 Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Pubmed 1.38E-08 3.16E-03 8.36E-06 1.08E-04 13 22 "OLIG2,FABP7,TUBB3,GFAP,RBPJ,MBP,PDGFRA,PRPH,SOX8,S100B,SLC1A3,SOX10,TAL1" Pubmed 16892058 The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Pubmed 1.38E-08 3.16E-03 8.36E-06 1.08E-04 13 22 "PROM1,CDH2,ELAVL3,ELAVL4,TUBB3,GAP43,GFAP,MAP2,NEUROD1,PAX6,CUX2,PARD3,SLC17A6" Pubmed 16273093 A quantitative protein interaction network for the ErbB receptors using protein microarrays. Pubmed 1.38E-08 3.17E-03 8.36E-06 1.08E-04 28 90 "BCAR3,APBB1,APBB2,NUMB,NUMBL,CHN1,CHN2,SH2B1,APPL1,EGFR,ERBB2,ERBB4,FER,FGFR1,FGR,JAK1,JAK2,MATK,SHC3,PIK3R1,SH3BP2,SLA,DOK5,TNS2,DOK6,VAV1,VAV2,ANKS1B" Pubmed 22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Pubmed 1.54E-08 3.53E-03 9.16E-06 1.18E-04 21 55 "ADCY5,SFMBT2,MADD,FOXN3,AKAP6,CRY2,DGKB,CHL1,GCK,KDM2B,GRB10,IGF1,LMO1,LYPLAL1,PCSK1,PROX1,VPS13C,UHRF1BP1,SYN2,TCF7L2,DPYSL5" Pubmed 15815621 Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Pubmed 1.54E-08 3.53E-03 9.16E-06 1.18E-04 81 442 "GALNT13,ADD1,ADD2,RNF150,CCDC74A,KIF1A,BARD1,ST3GAL5,CDK5R2,LRRFIP1,CHN1,NDST3,NRXN1,NGEF,CNGA3,TMEM155,CNRIP1,FEZ2,DBI,YTHDC1,E2F6,KLHL5,SPEG,POLR1B,UBE2E3,RGPD5,STAMBP,TBR1,GAB1,MTHFD2,DNER,GBX2,SULT1C4,MMADHC,GPR75,ZNF638,EML4,GRK4,RABL2A,GPR45,HNMT,AGFG1,C2orf72,ITGAV,SFXN5,LIMS1,ASPRV1,GPR155,MAT2A,NEUROD1,FIGN,CARF,KCNIP3,AP1AR,CSRNP3,HES6,ASIC4,HSPA4L,DOCK10,ANKRD36,PALLD,KDM3A,ITPRID2,CEP68,NEU4,CLASP1,SLC19A3,PUM2,FAM200B,TSN,RFTN2,TMEFF2,XPO1,REEP1,TMEM237,LMAN2L,RNF103,SCG2,TMEM163,HNRNPA3,SLC4A10" Pubmed 12106288 A Collection of cDNA Clones with Specific Expression Patterns in Mouse Brain. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "ABAT,CBLN1,DBI,GABRA1,NCKAP1,KIF5C,NAP1L1,SEPT4,PRKACB,NAPB" Pubmed 20847152 Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "PCDH19,CDH8,ETV1,TBR1,PCDH11X,L1CAM,PCDH8,PCDH9,RELN,CUX2" Pubmed 18854036 Loss of transforming growth factor-beta 2 leads to impairment of central synapse function. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "SLC32A1,GPHN,NLGN3,S100B,NLGN1,SYN1,SYN2,SYP,SLC17A7,SLC17A6" Pubmed 17699610 Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "DCT,OLIG2,FABP7,KIT,MBP,PLP1,SOX1,SOX2,SOX3,SOX10" Pubmed 18024993 Sall1 regulates mitral cell development and olfactory nerve extension in the developing olfactory bulb. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "CALB2,TUBB3,TBR1,GAD1,GAD2,GAP43,NCAM1,RELN,S100B,SALL1" Pubmed 18260139 Sall3 is required for the terminal maturation of olfactory glomerular interneurons. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "CALB1,CALB2,ETV1,TUBB3,GAD1,GAD2,SALL3,PAX6,RELN,SALL1" Pubmed 20519520 Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "DLGAP3,DLG4,PPP1R1B,GABRB3,GABRG2,GAD1,GAD2,GRIN1,CARF,SYP" Pubmed 22186729 Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Pubmed 1.55E-08 3.56E-03 9.16E-06 1.18E-04 10 13 "DCT,EDN3,EDNRB,FABP7,TUBB3,KIT,MITF,SOX2,SOX10,UCHL1" Pubmed 25071457 Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation. Pubmed 1.62E-08 3.72E-03 9.54E-06 1.23E-04 19 46 "CALB2,CCK,SLC32A1,DLX1,DRD1,ERBB4,ETV1,GAD2,NOS1,PENK,RASGRF2,RORB,SNAP25,SST,TAC1,TAC3,CUX2,SLC17A7,SLC17A6" Pubmed 21386911 "Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways." Pubmed 1.62E-08 3.73E-03 9.54E-06 1.23E-04 43 179 "ADCY8,ATP1A2,CACNB4,SLC22A6,LY86,COL9A1,RBM39,SLC32A1,SNCAIP,RASSF2,MAGI2,ELAVL4,PIPOX,EYA1,C2orf88,CGREF1,ALDH1L1,GPD1,GPM6A,GPM6B,CCDC184,GRIA4,IGF1,LIX1,AQP11,KITLG,MYBPC1,NPY,OPCML,PDGFRA,GNG2,SERPINI1,NXPH1,PTN,PID1,TMEM100,DZIP1,APOM,VWCE,SYNPO2,VLDLR,SLC13A3,SEMA3B" Pubmed 20602615 Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Pubmed 1.71E-08 3.92E-03 1.00E-05 1.29E-04 45 192 "ACHE,ADORA1,ADORA3,ADRB2,AGT,CCK,CCKBR,SCARB1,CHRM1,CALY,EDN1,PRKAG2,FLT1,GABRA2,GABRA4,GAD1,GAD2,DISC1,GNAO1,NR3C1,HRH3,HMGCR,HNMT,HP,HTR2A,IGF1,MTTP,NPY,OLR1,PFKP,ABCB1,PIK3CD,PIK3R1,PKM,PLIN1,PPARA,RXRA,RXRG,SLC12A4,SST,APOM,ABCC8,TCF7L2,TEK,TNFRSF1B" Pubmed 2137249 Diabetogenic response to streptozotocin varies among obese yellow and among lean agouti (BALB/c x VY)F1 hybrid mice. Pubmed 1.75E-08 4.01E-03 1.02E-05 1.31E-04 12 19 "APC,CALB1,CALB2,ELAVL3,ELAVL4,FABP7,TUBB3,GFAP,NEUROD1,PROX1,SOX2,SOX10" Pubmed 18799476 Identification of Arx transcriptional targets in the developing basal forebrain. Pubmed 1.75E-08 4.01E-03 1.02E-05 1.31E-04 12 19 "VAT1L,CALB1,HAP1,EBF1,GBX2,LMO1,MEF2C,KITLG,MAGEL2,SOX8,ARX,SST" Pubmed 17507395 Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia. Pubmed 1.75E-08 4.01E-03 1.02E-05 1.31E-04 12 19 "ASCL1,ELAVL3,ELAVL4,FABP7,TUBB3,GAP43,KIT,MAP2,NOS1,RET,SOX10,UCHL1" Pubmed 21078624 Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Pubmed 1.82E-08 4.17E-03 1.05E-05 1.36E-04 33 119 "ACTN1,ACTN2,HHATL,C1QTNF1,LTBP4,CACNA1A,KALRN,ARHGAP22,DNAJB5,SUMF2,CRMP1,GPRASP1,IP6K1,OLIG1,ABI1,EFEMP1,NELFCD,ZCCHC17,KHDRBS3,SRRM4,TUBB2B,MATK,MATN2,NELL1,NELL2,PCSK5,ATXN7,SCP2,PUF60,HECW1,ITPRID2,MPRIP,RIMBP2" Pubmed 11214970 Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Pubmed 1.82E-08 4.19E-03 1.06E-05 1.36E-04 30 102 "BRINP2,TMEM108,DLC1,CECR2,DOCK7,KNDC1,LRRCC1,KIAA1755,DISP2,FTO,VEPH1,ZYG11B,SETD5,CNTNAP3,KIF21A,AMBRA1,FHOD3,NBPF1,SPHKAP,TET1,CPEB4,BDP1,TEX2,KLHL4,SYNE1,ASXL3,DDHD1,BHLHB9,WNK2,SENP7" Pubmed 23042739 NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis. Pubmed 1.90E-08 4.36E-03 1.09E-05 1.41E-04 11 16 "CALB1,CALB2,TBR1,GFAP,GRIK4,NFIX,PAX6,PROX1,RELN,SLC1A3,SOX2" Pubmed 15572149 The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Pubmed 1.90E-08 4.36E-03 1.09E-05 1.41E-04 11 16 "CALB2,GFAP,L1CAM,MAP2,MAPK8,MAPK9,MAPK10,PTK2,SNAP25,MAPK8IP3,STXBP1" Pubmed 21795542 Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. Pubmed 1.92E-08 4.41E-03 1.10E-05 1.42E-04 18 42 "LGR5,BMPR1B,PLPPR4,EPHA5,CDHR1,PCDH17,FAM19A2,HPCA,IFI16,IGF1,NPR2,PCDH8,PCDH9,CYTL1,PROX1,NTNG1,ZFPM2,FZD3" Pubmed 22689450 Regulation of archicortical arealization by the transcription factor Zbtb20. Pubmed 1.93E-08 4.44E-03 1.11E-05 1.43E-04 14 26 "NRP2,CALB2,LHX2,EMX2,EPHB1,ETV1,FOXG1,GRIK4,INSM1,KITLG,NEUROD1,PAX6,SOX2,SATB2" Pubmed 22232070 "Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1." Pubmed 1.93E-08 4.44E-03 1.11E-05 1.43E-04 14 26 "AXIN2,FABP7,TUBB3,FGFR3,FOXG1,TBR1,GLI2,RBPJ,HES5,MAP2,MSI1,PAX6,SOX2,NR2E1" Pubmed 7829101 Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Pubmed 2.00E-08 4.60E-03 1.14E-05 1.48E-04 27 86 "ACTN1,DYNLL1,QKI,COL9A1,PREPL,PDCD6IP,KATNAL1,EYA1,FGF12,GFRA1,STXBP5,HECTD2,RSPO2,NEFM,PDE4D,PENK,PTN,FBXW7,SATB1,ATXN7,TNFRSF19,EPC1,NMNAT2,GLT8D1,ZNF423,TEK,REEP1" Pubmed 18498732 Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves. Pubmed 2.30E-08 5.29E-03 1.31E-05 1.69E-04 16 34 "MRTFA,LDB2,CHRNB2,ETV1,TUBB3,GFRA1,GFRA2,NCAM1,NEFH,NTRK2,NTRK3,MAPK3,PRPH,RET,TAC1,TRPC3" Pubmed 21706016 Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. Pubmed 2.33E-08 5.36E-03 1.32E-05 1.71E-04 30 103 "MAP4K3,SYNJ1,ARHGEF7,EPS15L1,DOCK4,SIRPA,DNM1,DNM2,EGFR,STAMBP,GAB1,NCKAP1,STARD10,MAP4K5,GAREM2,TTYH2,ARHGAP12,PIK3AP1,AFDN,GIT1,PIK3R1,PPP5C,RBBP6,KIRREL1,HUNK,RADIL,ELMO2,CLASP2,WIPF1,WIPF2" Pubmed 11812828 Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Pubmed 2.36E-08 5.41E-03 1.33E-05 1.72E-04 34 126 "MADD,FAM19A5,CNIH3,PARD6A,KBTBD11,DNAJB6,ELAVL2,PAN3,MRPL10,STAU2,STAG2,FERMT2,TOX2,SCRT2,KCNQ2,AFDN,CCDC13,PKM,ANKHD1,PTX3,RDX,DUSP15,ZFHX4,RPL38,LGR4,SPTAN1,SRPK2,AJAP1,AGTPBP1,FRYL,FAM124A,FLRT2,VIPR2,MEIS3" Pubmed 19167335 Large-scale structural analysis of the classical human protein tyrosine phosphatome. Pubmed 2.47E-08 5.68E-03 1.40E-05 1.80E-04 19 47 "ALK,PKP4,CDH2,EGFR,TNK2,ERBB2,GAB1,GHR,JAK2,KIT,PDPK1,MAPK3,PTPRB,PTPRE,PTPRG,PTPRO,PTPRZ1,TEK,TIE1" Pubmed 26687479 "The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis." Pubmed 2.75E-08 6.32E-03 1.55E-05 2.00E-04 74 396 "ABCF1,MTA3,AK2,SPOP,EP400,API5,CCAR2,PRC1,CFL2,LETMD1,MAGED1,NCOR2,CS,EBF1,PHC2,TMTC1,YAF2,ING4,MRPL37,ARMCX1,AMZ2,PRAM1,TUBB3,TUBB4A,SCML2,FECH,SPECC1,SALL3,TUBGCP4,TXNL4A,TCERG1,KDM2B,CECR2,PCLO,TUBA1C,DIDO1,KAT7,SOX21,PSIP1,ZIC5,TUBB2B,NACA,NDUFA5,PCMT1,EXOSC10,PPP2R5E,NDUFS7,PSMD13,RAD52,PBRM1,RPRD1A,PCMTD2,RPE,RPL38,CLIP1,SALL1,FBXO11,SMARCC2,TRERF1,SOX2,ERC1,PEG10,STAU1,GANAB,TBL1X,TCF4,SATB2,TP53BP1,TSC2,ZIC2,ZIC3,TUBA1A,PCDH15,MRPL47" Pubmed 21238928 Rheb1 is required for mTORC1 and myelination in postnatal brain development. Pubmed 2.88E-08 6.62E-03 1.61E-05 2.08E-04 13 23 "APC,OLIG2,TUBB3,GFAP,MAG,MAP2,MAPT,MBP,MOBP,MOG,PDGFRA,PLP1,TSC2" Pubmed 16818446 FGF signalling generates ventral telencephalic cells independently of SHH. Pubmed 2.88E-08 6.62E-03 1.61E-05 2.08E-04 13 23 "ASCL1,LHX2,EBF1,EMX2,FGFR1,FGFR3,FOXG1,GAD1,HES5,NPY,PAX6,PROX1,CNTN2" Pubmed 27149841 Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. Pubmed 2.88E-08 6.62E-03 1.61E-05 2.08E-04 13 23 "APC,MYRF,OLIG1,OLIG2,GFAP,GPR37,OPALIN,MAG,MBP,MOG,NKX2-2,PAX6,PDGFRA" Pubmed 24351932 Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity. Pubmed 2.88E-08 6.62E-03 1.61E-05 2.08E-04 13 23 "ADORA2A,PCDH10,CALB1,CALB2,CHRM4,DRD1,EBF1,MEF2C,NOS1,PAX6,PDYN,PENK,TAC1" Pubmed 28598330 Analysis of SUMO1-conjugation at synapses. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "GPHN,GRIK2,GRIN1,GRM7,RIMS1,STX1A,SYN1,SYP,SYT1" Pubmed 18509043 GPR56 regulates pial basement membrane integrity and cortical lamination. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "CALB1,CALB2,ADGRG1,FABP7,TUBB3,PPP1R1B,TBR1,RELN,SLC1A3" Pubmed 26520399 Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "SLIT2,L1CAM,NKX2-2,PAX6,PROX1,ROBO1,ROBO2,SLIT1,SOX2" Pubmed 9882498 Synapse formation by hippocampal neurons from agrin-deficient mice. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "DLGAP1,SV2B,SV2A,DLG4,GPHN,GABRB3,GRIA1,SYN1,SYP" Pubmed 12456676 "Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1." Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "AMPH,BIN1,SYNJ1,DNM1,DNM2,SH3GLB1,SH3GL2,SH3GL3,SYN1" Pubmed 12091317 Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "CALB2,LHX2,EMX2,GAP43,GFAP,L1CAM,MAP2,RELN,CNTN2" Pubmed 11163262 Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "CALB1,CALB2,DLX1,TUBB3,GAD1,MAP2,NPY,RELN,SST" Pubmed 23478408 Planar cell polarity genes control the connectivity of enteric neurons. Pubmed 3.39E-08 7.79E-03 1.85E-05 2.40E-04 9 11 "CALB2,CELSR3,ELAVL3,ELAVL4,TUBB3,KIT,NOS1,RET,FZD3" Pubmed 21658586 Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors. Pubmed 3.66E-08 8.40E-03 2.00E-05 2.58E-04 14 27 "NRP2,CALB1,CALB2,DLX1,ETV1,GAD1,NKX6-2,NPY,POU3F4,PTCH1,SOX6,ARX,SST,ZIC1" Pubmed 20811636 "The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1." Pubmed 3.89E-08 8.94E-03 2.12E-05 2.74E-04 45 197 "RALGAPA1,ACLY,ACTN1,AP2A2,ARHGAP20,CDK13,DDX3Y,ATP2B1,ATP2B3,DST,CCNT1,MYOM2,SRSF11,TBPL1,RASGEF1C,G3BP2,SEC16A,DMD,DOCK2,ATN1,AASS,F5,PRMT5,SEC24B,CLASRP,ATXN2L,IDH3A,PAXBP1,MARK3,NEXMIF,NME4,PCMT1,KCTD15,REV3L,SNX22,SFPQ,HSPA4L,ZC3H13,SPTAN1,GANAB,SYNE2,SYNE1,TBC1D15,TFIP11,DHX33" Pubmed 23312518 "Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons." Pubmed 3.96E-08 9.10E-03 2.14E-05 2.76E-04 15 31 "CALB1,ZEB2,DLX1,OLIG2,GAD1,GBX2,KCNMB4,NOS1,NPY,SOX6,SST,TACR1,CUX2,ZEB1,TMEM163" Pubmed 19666558 Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Pubmed 3.96E-08 9.10E-03 2.14E-05 2.76E-04 15 31 "CLTA,CLTB,CLTC,DNM1,HEYL,RBPJ,HES5,OCRL,EPN1,HES6,ITSN1,EPN2,SYT1,HEY1,HEY2" Pubmed 18199763 Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. Pubmed 3.96E-08 9.10E-03 2.14E-05 2.76E-04 15 31 "CALB2,CHRM4,NGEF,NECTIN3,EBF1,PPP1R1B,GRIA1,MAP2,MEIS2,RELN,FIGN,KCNIP2,SST,UNC5D,NETO1" Pubmed 23396189 Gli3 is required in Emx1+ progenitors for the development of the corpus callosum. Pubmed 3.98E-08 9.14E-03 2.14E-05 2.76E-04 12 20 "AXIN2,CALB1,CALB2,SLIT2,FABP7,TBR1,GFAP,L1CAM,NFIA,ROBO1,SLIT1,SATB2" Pubmed 16971467 Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. Pubmed 3.98E-08 9.14E-03 2.14E-05 2.76E-04 12 20 "DLX1,EBF1,EMX2,EN2,TUBB3,FOXG1,GBX2,PAX6,IRX1,FEZF2,TCF4,TCF7L2" Pubmed 15648052 Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. Pubmed 3.98E-08 9.14E-03 2.14E-05 2.76E-04 12 20 "ATP1A1,ATP1A3,CAMK2A,DBN1,DPYSL2,ENO2,GAP43,GNAS,MBP,RAB3A,STX1B,VAMP1" Pubmed 12107410 "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants." Pubmed 4.05E-08 9.30E-03 2.17E-05 2.80E-04 31 111 "ADD1,TAOK1,ATP2B2,COL9A1,CP,NCOR2,NTM,ABCC9,F5,FOXO3,FLT1,SYT17,MDFI,MDM4,NFIA,CNOT4,PAX6,ENPP2,PLP1,POLR2F,ATXN2,AMBRA1,SYBU,SEC31A,TMCC1,ZSWIM8,CEP68,CAMSAP2,EHBP1,TEK,BEST1" Pubmed 19946888 Defining the membrane proteome of NK cells. Pubmed 4.45E-08 1.02E-02 2.38E-05 3.07E-04 170 1168 "ABCF1,ABR,ACLY,ADAR,GRAMD1B,ESYT2,KIDINS220,AP2A1,INTS2,OSBPL8,C1QTNF3,ANXA7,API5,DDX3Y,DYNLL1,CHID1,ATP2B1,KSR1,AP1M1,CAMK2D,CAMK2G,CANX,CD81,LRBA,CDC42,EPS15L1,CLCN3,CLTA,CLTC,FADS2,COX4I1,ACBD5,NCOR1,NCOR2,OSBPL3,CHD5,MATR3,INTS1,DCTN1,ELMO1,B3GAT3,MED12,DOCK2,PDCD6IP,DNAJB6,FARSB,DNM1L,FIS1,GOLT1B,APH1A,PLXNC1,EIF4G1,EIF4G2,TNK2,STARD3NL,CD320,F5,ACSL4,ATP8A1,AGAP2,SYNCRIP,EVL,NOP56,NELFCD,ATP2C1,ERGIC3,CELF1,STAU2,OGA,STAG2,GAA,HBS1L,GHDC,ERAP1,INPP5K,TUBGCP4,GNAS,GOLGB1,EML4,CNTRL,RFFL,CIT,GYG1,HBA1,MAN1B1,NCKAP1L,DDX19B,ATXN2L,ELOVL5,HNRNPK,HSP90AA1,IFI16,IL6ST,KIF2A,KIF5A,KLC1,IPO5,KTN1,LSS,MIA2,GIT1,MYO5A,MYO6,HNRNPM,NAP1L1,NCAM1,NF1,SLC11A2,NUCB1,OPA1,PDE3B,PDGFRA,OLA1,PFKP,PIK3C2A,PIK3R1,XRN1,EXOSC10,MBOAT7,MED1,CEP41,PRPH,GDPD1,PSMD13,PIGG,OCIAD1,PEX2,MYH14,ALG9,RPS20,ATXN2,SCP2,MYO18A,DOCK10,FNDC3A,CDK5RAP3,SMARCA4,IFT122,LMBRD1,KDM3A,GLT8D1,MYCBP2,CLASP2,LARP4,NCDN,STAU1,GANAB,PRRC2C,MMS19,ATP11A,EXOC7,ALG1,MGRN1,CLASP1,DOCK9,AKNA,SLC44A1,LRRC8A,TMPO,EIF4ENIF1,KLC2,XPO1,TMEM237,LRP8,DOCK8,CERS6,ZDHHC20,AAAS,FXR1,LAS1L" Pubmed 22094256 A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. Pubmed 4.47E-08 1.03E-02 2.38E-05 3.08E-04 24 73 "PRX,SRSF11,TJP2,NIPBL,ABI2,FOXM1,FOXO3,SORBS1,PPARGC1A,MSL3,CLASRP,SRSF12,NUMA1,CASC3,TRA2B,SOX5,SOX10,POGZ,ANKRD12,ZEB1,SIRT1,SYNPO2,SSBP2,EIF4ENIF1" Pubmed 20881960 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Pubmed 4.57E-08 1.05E-02 2.43E-05 3.14E-04 45 198 "SYN3,NCKAP5,CASKIN1,ZFAT,LCORL,JAZF1,NOG,SOCS5,ZBTB24,CCDC3,STARD3NL,ANKRD13B,DNAJC27,EFEMP1,FER,FOLH1,DOT1L,ADAM28,SPIN1,DIPK1A,KCNJ16,LYPLAL1,MEF2C,GIT1,MYO9A,SLCO1C1,NUCB2,PCSK5,SERPINE2,SMOX,PKN2,PRKCZ,PTCH1,PEX2,SCMH1,ADAMTS17,FAM208A,FBXW11,HHIP,TNS1,MICAL1,ZNF142,ZBTB38,ADAMTSL3,ADAMTS10" Pubmed 28219675 Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Pubmed 4.62E-08 1.06E-02 2.45E-05 3.17E-04 18 44 "AXIN2,ASCL1,NRP2,INA,SLIT2,LHX2,OLIG2,EFS,GBX2,PAX6,IRX1,ROBO1,ROBO2,SLIT1,ROBO3,TAL1,CNTN2,TCF7L2" Pubmed 28190767 An Interaction Landscape of Ubiquitin Signaling. Pubmed 4.66E-08 1.07E-02 2.47E-05 3.19E-04 83 468 "ACTN1,BRAP,AP2A1,AP2A2,OSBPL8,OGT,USP37,KIF1A,BARD1,HAP1,CANX,ARHGEF2,CDC27,EPS15L1,ZFYVE9,PLAA,HECTD1,UBXN2A,CTNND1,TCAF1,TBC1D5,DBT,SPATA2,COPS7A,DDX46,USP3,DNM2,PDCD6IP,TOM1,OPTN,COPS4,TNK2,GPHN,ANKRD13B,ERCC2,ATP5PD,USP16,NPTN,NEURL4,USP19,DDX19B,ELOVL5,GABARAPL2,ITGAV,MYL3,MYO5A,MYO6,NFIA,PDPK1,OLA1,SERPINE2,PLEC,EPN1,PMS2,MBOAT7,PPM1B,LAMA1,PSMD13,USP47,RNF220,PCMTD2,RMI1,ITSN1,CCDC92,URGCP,EPN2,PALLD,SPTAN1,TAB2,FCHO1,NSFL1C,KLHL7,ALG1,AGTPBP1,UBC,UBE3A,UCHL1,TOM1L2,CCDC14,TBC1D15,ZFAND5,SNX27,UBE3B" Pubmed 11572484 Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. Pubmed 4.71E-08 1.08E-02 2.49E-05 3.21E-04 22 63 "CSMD2,GPRIN1,XKR4,SLC25A25,CSMD3,FMNL2,KLHL32,TMEM132B,ELFN2,PSMG3-AS1,SLITRK1,CCDC85A,GALNT13,RNF157,PWWP2A,TRAPPC9,SCIN,NEK1,RIPOR1,LGI2,ITPRID2,CSMD1" Pubmed 19709629 The cell-intrinsic requirement of Sox6 for cortical interneuron development. Pubmed 4.90E-08 1.13E-02 2.56E-05 3.31E-04 11 17 "CALB2,OLIG2,TBR1,GAD1,KCNC1,KCNC2,NPY,SOX6,SOX5,SST,SATB2" Pubmed 23575864 Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia. Pubmed 4.90E-08 1.13E-02 2.56E-05 3.31E-04 11 17 "MYRF,MED12,OLIG2,MED12L,GPR17,MBP,NKX2-2,PDGFRA,PLP1,SOX2,SOX10" Pubmed 8889549 "Generation and analysis of 280,000 human expressed sequence tags." Pubmed 4.92E-08 1.13E-02 2.56E-05 3.31E-04 65 336 "ADARB2,ADD2,CDC7,SYT13,SMIM29,DST,CACNB2,CDH10,CFL2,FOXN3,SNCAIP,PDE4DIP,DAPK1,SPATA2,TMCC2,EGR3,EIF1,AMOTL2,USP21,PNMA2,ZMAT1,WASHC2A,GJB1,COPS8,GOLGB1,GPR34,GRK4,PTPRT,HLF,ZNF491,HP,HPR,IL6R,MRPL42,ZNF92,MYBPC1,NAP1L1,DDR2,PIK3CD,FTO,SH3KBP1,RFX2,PBRM1,UEVLD,DGLUCY,MAPK12,LINC00461,BTBD3,KIF13A,ZNF415,TMCC1,CLUAP1,SPART,DNMBP,SIK3,CYB561A3,TJP1,PARD3,SYNPO2,FAM155A,PCDH20,ZNF138,WNK1,NAV2,FAM47E" Pubmed 10373510 Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2D,RASGRF1,RASGRF2" Pubmed 21795692 Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "DLGAP1,DLG4,SHANK1,ABI1,BAIAP2,GRIA1,GRIN1,GRM1,GRM5,SHANK2" Pubmed 18400903 Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "CCK,GRIA2,TLX1,MAPT,PDYN,PENK,SST,TAC1,TAC3,TRPC3" Pubmed 19712103 IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "CALB1,CALB2,TUBB3,TBR1,GAD2,GFAP,IGF1,NCAM1,PAX6,RELN" Pubmed 18940588 Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "LHX2,ETV1,TUBB3,FOXG1,TBR1,L1CAM,NEFH,NEUROD1,RORB,CUX2" Pubmed 16615895 Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Pubmed 4.95E-08 1.14E-02 2.56E-05 3.31E-04 10 14 "ASCL1,CALB1,CALB2,EBF1,ERBB4,TUBB3,FOXG1,GAD1,L1CAM,MEIS2" Pubmed 15461802 A genome annotation-driven approach to cloning the human ORFeome. Pubmed 5.27E-08 1.21E-02 2.72E-05 3.52E-04 59 294 "DGCR6,SYN3,ADORA2A,AP1B1,PLA2G6,MRTFA,SLC2A11,BID,MTMR3,P2RX6,LARGE1,FBXO7,TMEM184B,SULT4A1,PICK1,GAL3ST1,CRYBB1,CSNK1E,SLC25A18,TOM1,CACNG2,TUBA8,CSDC2,GGT5,AIFM3,MCHR1,GSTT2,RABL2A,PACSIN2,KCNJ4,LINC00634,MGAT3,MN1,ZDHHC8,POLR2F,PPARA,CASTOR1,TUG1,EMID1,FOXRED2,MAPK12,PEX26,SOX10,SEPT3,MLC1,KIAA0930,RBFOX2,SEZ6L,RASD2,TST,HIRA,EIF4ENIF1,PITPNB,BCL2L13,ZNF70,ZNF74,POLR3H,TFIP11,HPS4" Pubmed 15561718 Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. Pubmed 5.53E-08 1.27E-02 2.85E-05 3.68E-04 17 40 "ADD3,SEMA6A,APP,COG1,CASP8AP2,ETV1,TCERG1,STMN2,MEF2C,HNRNPM,SATB1,CAMSAP2,KAT6B,HIRA,ZNF24,WNK1,NELFE" Pubmed 20301334 Dystonia Overview Pubmed 5.56E-08 1.28E-02 2.86E-05 3.69E-04 25 79 "ADAR,PLA2G6,ATP1A3,SGCE,CBS,TPP1,CP,PNKD,ATN1,GALC,GATM,MMADHC,GNAL,PAH,PLP1,FA2H,POLG,PRRT2,SLC30A10,SLC6A8,SLC20A2,VPS13A,SLC19A3,ATP13A2,JPH3" Pubmed 16221301 "Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events." Pubmed 5.72E-08 1.32E-02 2.94E-05 3.79E-04 13 24 "GPRASP2,TCEAL2,GPRASP1,ARMCX4,ARMCX2,ARMCX1,TCEAL6,TCEAL5,BEX5,BEX1,BHLHB9,BEX4,TCEAL7" Pubmed 9455484 Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. Pubmed 6.14E-08 1.41E-02 3.14E-05 4.06E-04 20 54 "CDC42BPA,PLCH2,CHD5,PDE4DIP,SDC3,NOS1AP,DNAJC6,CEP170,PLPPR4,RABGAP1L,TMCC2,SH3GLB1,DISC1,PRKCZ,RAP1GAP,KIF21B,NMNAT2,POGZ,SZT2,SNX27" Pubmed 12923177 Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "PPFIA4,PPFIA2,PPFIA1,PPFIA3,CAST,ERC2,GIT1,ERC1" Pubmed 10531433 Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "DLG4,GPHN,GABRA2,GABRG2,GRIA2,GRIN1,KIF1B,SYP" Pubmed 11799060 Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "OLIG2,ERBB2,GFAP,MAG,MBP,PDGFRA,PLP1,SOX10" Pubmed 19625254 Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "CNTNAP1,CNTNAP2,GFAP,KCNA1,MAP2,PLEC,NFASC,SYP" Pubmed 20071536 Sox2 induces neuronal formation in the developing mammalian cochlea. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "TUBB3,MAP2,NEFH,NEUROD1,SOX1,SOX2,SOX3,SOX10" Pubmed 27800545 Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "PICK1,DLG2,DLG4,GRIA1,GRIA2,GRIN1,SYNDIG1,SYP" Pubmed 24917275 Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "TBR1,GPM6A,GPM6B,L1CAM,MAP2,PLP1,SOX5,SATB2" Pubmed 21356198 Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "BSN,CBLN1,NRXN1,NRXN2,SLC32A1,NLGN1,SLC17A7,CBLN2" Pubmed 25653379 Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "ANK3,SPTBN4,GFAP,KCNA1,NRCAM,GLDN,BCAN,NFASC" Pubmed 15479642 "Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment." Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "ANK3,CALB1,GAD1,GAD2,HCN1,SLC6A1,NFASC,SYN1" Pubmed 9051806 Expression of glutamate receptor subunit genes during development of the mouse retina. Pubmed 6.30E-08 1.45E-02 3.15E-05 4.07E-04 8 9 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 10843805 A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5. Pubmed 6.79E-08 1.56E-02 3.38E-05 4.36E-04 15 32 "CACNA2D1,CD38,CRMP1,DPP6,SEMA3D,EN2,EPHA5,FGFR3,GABRA4,GABRB1,HTR5A,KCNH2,KCNK3,QDPR,SLC30A3" Pubmed 23667531 The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. Pubmed 6.79E-08 1.56E-02 3.38E-05 4.36E-04 57 282 "ARID1A,MTA3,INTS2,ZNF687,EP400,MIER1,ZBTB10,CCAR2,CCNT1,ARMC8,CLOCK,NCOR1,CTNND1,INTS1,ZEB2,MYEF2,SEC16A,DNAJB6,DNM1L,PHC2,SUGP2,EPS8,TUBB3,AMOTL2,SMC2,AHCYL1,WASHC2A,BRD8,MSL3,FERMT2,MSL1,IPO5,MEIS2,MKLN1,OLA1,PFKP,PPP2R5C,ZFHX4,RNH1,SOX6,CHD9,INTS9,TRERF1,SOX2,SP2,SUPT5H,MMS19,SMG6,SIN3B,TCF12,ZNF384,ZMYND8,TUBB2A,INTS3,TUBA1A,NUP214,LAS1L" Pubmed 21041608 Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. Pubmed 7.00E-08 1.61E-02 3.47E-05 4.49E-04 18 45 "CNR1,DRD1,PPP1R1B,FGFR1,GAD1,DISC1,GPM6A,GRM3,HTR2A,LRRTM1,MTR,NOS1,NPY,P2RX7,PRODH,RGS4,ROBO1,PRDM2" Pubmed 19531213 Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. Pubmed 7.60E-08 1.75E-02 3.76E-05 4.86E-04 30 108 "SYNJ1,SYNJ2,MAP7,PRC1,SEPT7,CDC27,ELMSAN1,POM121,DNM1,DNM2,PDCD6IP,KCTD3,SRRM1,SEPT9,TUBGCP4,PSRC1,PSIP1,SYNPO,HNRNPK,MAP4,ANLN,SH3KBP1,ATXN2,SH3BP2,LIMCH1,ERC1,SEPT8,PHLDB1,WIPF1,WIPF2" Pubmed 25971728 Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2. Pubmed 8.46E-08 1.94E-02 4.15E-05 5.36E-04 12 21 "CDH8,LHX2,EMX2,ETV1,TUBB3,TBR1,NEFH,PAX6,RORB,STX1A,SATB2,CUX2" Pubmed 22705452 PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Pubmed 8.46E-08 1.94E-02 4.15E-05 5.36E-04 12 21 "PTBP2,CDH2,OLIG2,TUBB3,TBR1,GFAP,PAX6,PKM,POU3F2,PRKCZ,S100B,TJP1" Pubmed 27076429 Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System. Pubmed 8.46E-08 1.94E-02 4.15E-05 5.36E-04 12 21 "ASCL1,CALB1,ELAVL3,ELAVL4,FABP7,NEUROD1,NOS1,NPY,RET,S100B,SOX2,SOX10" Pubmed 22726835 Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Pubmed 8.46E-08 1.94E-02 4.15E-05 5.36E-04 12 21 "UNC5A,CDH8,CDH10,DCC,DSCAM,FOXG1,NEUROD1,NHLH1,RELN,UNC5B,UNC5D,SLC17A6" Pubmed 11060228 The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Pubmed 8.46E-08 1.94E-02 4.15E-05 5.36E-04 12 21 "ASCL1,CALB1,CALB2,DLX1,EBF1,PPP1R1B,GAD1,NEUROD1,NKX2-2,PAX6,PENK,PTN" Pubmed 19521566 The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease. Pubmed 8.55E-08 1.96E-02 4.18E-05 5.40E-04 45 202 "APP,AQP6,ARNTL,ALDH4A1,BMP7,BTRC,CLDN10,CDH2,CHRNB2,SLC22A6,CNTN1,SLC25A27,SLC4A8,CPS1,PYGO1,ZEB2,DPP6,OLIG2,GAD1,GART,IGSF5,GLUL,GPR22,MCHR1,GRIK4,ATOH8,NEGR1,CDH20,LSAMP,MXI1,SLCO1C1,NHLH1,SLC26A11,SLC2A5,SLC6A1,SLC12A2,NPAS3,MESP1,SLC37A2,TAL1,HEY1,HEY2,TRPC3,PORCN,SLC13A3" Pubmed 12514217 Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "SLIT2,FABP7,TBR1,GFAP,NFIA,ROBO1,ROBO2" Pubmed 24987331 "Altered GABAergic markers, increased binocularity and reduced plasticity in the visual cortex of Engrailed-2 knockout mice." Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CALB1,SLC32A1,EN2,GAD1,NPY,SST,SLC17A7" Pubmed 9280305 Clathrin interacts specifically with amphiphysin and is displaced by dynamin. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "AP2A1,AP2A2,AP1B1,AMPH,BIN1,CLTC,DNM1" Pubmed 19342380 Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "DLG3,NCALD,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 16722236 The role of SNARE proteins in trafficking and function of neurotransmitter transporters. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "GAD1,CPLX1,RAB3A,RIMS1,SNAP25,STX1A,STXBP1" Pubmed 7913715 Organization of the embryonic and early postnatal murine hippocampus. I. Immunocytochemical characterization of neuronal populations in the subplate and marginal zone. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CALB1,CALB2,CCK,MAP2,NPY,SNAP25,SST" Pubmed 12975355 Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CNTNAP1,CNTNAP2,KCNA2,MAG,NFASC,EPB41L3,CNTN2" Pubmed 1310861 Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK5" Pubmed 18490449 "Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane." Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CNTNAP1,CALB1,OPALIN,MAG,MBP,MOG,PLP1" Pubmed 15102707 Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "OLIG2,GFAP,MBP,PLP1,SOX8,S100B,SOX10" Pubmed 16514356 Expression of olig2 in retinal progenitor cells. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CALB1,CALB2,OLIG2,TUBB3,GFAP,GLUL,NEFH" Pubmed 17428973 Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "ADORA1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,PPP3CA" Pubmed 7560270 Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "GABRA2,GABRA3,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2" Pubmed 17332754 The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "APBA2,APBB1,APP,KIF2A,KLC1,CLSTN1,KLC2" Pubmed 17117441 Prox1 expression patterns in the developing and adult murine brain. Pubmed 8.87E-08 2.04E-02 4.20E-05 5.43E-04 7 7 "CALB2,OLIG1,OLIG2,TUBB3,GFAP,NEFH,PROX1" Pubmed 12466855 A gene expression map of human chromosome 21 orthologues in the mouse. Pubmed 9.13E-08 2.10E-02 4.32E-05 5.58E-04 37 151 "APP,PDXK,BACH1,SYNJ1,CFAP410,CBR1,CBS,JAM2,CLTC,C2CD2,ABCG1,OLIG1,DSCAM,RCAN1,DYRK1A,OLIG2,VPS26C,USP16,GART,IGSF5,GRIK1,PAXBP1,LSS,N6AMT1,NCAM2,PCBP3,SETD4,HUNK,S100B,ITSN1,SON,SAMSN1,DIP2A,TIAM1,TRPM2,TTC3,CFAP298" Pubmed 23314748 Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? Pubmed 9.24E-08 2.12E-02 4.36E-05 5.63E-04 40 170 "ACLY,KIAA1211,KLHL13,UNC79,CBR1,CDH2,CHGA,SLIT2,RTTN,SOCS5,ECE2,KIAA0586,C8orf34,TOM1,PHF20L1,EFS,MRPL37,TNRC6A,ZHX1,MAP4,PTOV1,HNRNPM,SNTG1,EPN1,HYDIN,PTH1R,KLHL11,UEVLD,SFPQ,SGK1,NBPF1,SYNE2,TAC3,DNAH7,CDH22,TIAM1,UBC,RPL7L1,TOM1L2,ZNF213" Pubmed 15164053 DNA sequence and analysis of human chromosome 9. Pubmed 9.62E-08 2.21E-02 4.53E-05 5.85E-04 69 371 "ALAD,KCNT1,MPDZ,IL33,KYAT1,PLAA,SLC24A2,CLTA,FAM189A2,TJP2,BRINP1,AIF1L,SEC16A,GNE,ECM2,FSD1L,ELAVL2,RABEPK,FKTN,SEMA4D,TMEM8B,FREM1,SPIN1,KIAA1958,PRRC2B,PRUNE2,PLPP7,SPACA9,ADAMTS13,CACFD1,SLC2A6,MAN1B1,JAK2,NPR2,PTPA,DIRAS2,APTX,CNTLN,PTCH1,RFX3,RGS3,RORB,RMI1,FAM102A,SH3GL2,CDK5RAP2,FAM219A,FNBP1,KDM4C,SPTAN1,KANK1,VPS13A,PHF24,SLC44A1,NACC2,LRRC8A,TMOD1,CDK20,TPM2,C9orf85,ANKRD20A2,FRRS1L,VLDLR,CRB2,ZNF189,SH3GLB2,ZFAND5,URM1,DOCK8" Pubmed 21192082 Dynamic spatiotemporal gene expression in embryonic mouse thalamus. Pubmed 1.01E-07 2.33E-02 4.76E-05 6.16E-04 16 37 "ASCL1,CHRD,BMP7,NOG,LHX2,FABP7,GBX2,GFRA1,GRIA1,GRM1,GRM3,KITLG,NKX2-2,PROX1,PTCH1,SLC17A6" Pubmed 26651292 A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis. Pubmed 1.09E-07 2.50E-02 5.08E-05 6.57E-04 13 25 "CARS,ETV1,TUBB3,FOXG1,TBR1,INSM1,PAX6,PSAT1,POU3F2,RORB,SATB1,SLC6A9,SOX2" Pubmed 25467980 NPAS1 represses the generation of specific subtypes of cortical interneurons. Pubmed 1.09E-07 2.50E-02 5.08E-05 6.57E-04 13 25 "CALB2,DLX1,OLIG1,ERBB4,FGFR1,FGFR3,TBR1,GAD1,NPY,RELN,ARX,NPAS3,SST" Pubmed 23341629 Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Pubmed 1.09E-07 2.51E-02 5.10E-05 6.59E-04 44 197 "ACHE,SNX30,BCAR3,ASPH,C1QC,CNOT8,FADS2,CP,NECTIN3,CRYM,SDC3,PLPPR4,CHRDL1,DLG4,MBNL2,SEZ6,SCARA3,ILDR2,GFAP,ADGRA3,GPM6B,KIFC3,LMO1,MEF2C,MSRA,RSPO2,NRCAM,PRTG,ZNF655,FXYD1,ELOVL2,ZIK1,PYGM,PID1,HKDC1,ARHGEF40,SLC12A4,MESP1,KAZN,THRA,MTMR14,BHLHB9,SEMA3B,DOCK8" Pubmed 12466854 Human chromosome 21 gene expression atlas in the mouse. Pubmed 1.10E-07 2.52E-02 5.10E-05 6.60E-04 37 152 "APP,PDXK,BACH1,SYNJ1,CFAP410,CBR1,CBS,JAM2,C2CD2,ABCG1,DSCAM,RCAN1,DYRK1A,OLIG2,VPS26C,USP16,GART,IGSF5,GRIK1,PAXBP1,LSS,N6AMT1,NCAM1,NCAM2,PCBP3,SETD4,HUNK,S100B,ITSN1,SON,SAMSN1,DIP2A,SLC37A2,TIAM1,TRPM2,TTC3,CFAP298" Pubmed 25977363 Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo. Pubmed 1.13E-07 2.60E-02 5.27E-05 6.81E-04 15 33 "AXIN2,PCDH19,PCDH10,CHRD,NOG,GBX2,PCDH17,PCDH11X,PCDH8,PCDH9,PCDH18,MESP1,TCF4,TCF7L2,PCDH20" Pubmed 18448566 Neurogenin 2 has an essential role in development of the dentate gyrus. Pubmed 1.15E-07 2.64E-02 5.31E-05 6.86E-04 11 18 "ASCL1,ELAVL3,ELAVL4,OLIG2,TUBB3,GAD1,GFAP,GRIK2,NEUROD1,PDGFRA,PROX1" Pubmed 28049845 REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Pubmed 1.15E-07 2.64E-02 5.31E-05 6.86E-04 11 18 "ASCL1,CHRNB2,RIPOR2,CELSR3,OLIG2,GAD2,INSM1,MAP2,RCOR2,PROX1,TRIM67" Pubmed 18329113 "Genes, plasticity and mental retardation." Pubmed 1.15E-07 2.64E-02 5.31E-05 6.86E-04 11 18 "ARHGEF6,DLG3,DMD,L1CAM,NF1,OPHN1,PAK3,RELN,RAB3GAP1,UBE3A,VLDLR" Pubmed 23482494 Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord. Pubmed 1.17E-07 2.69E-02 5.40E-05 6.98E-04 14 29 "APC,ASCL1,MMD2,OLIG2,GFAP,GLI2,FGFBP3,MBP,NFIA,NKX2-2,PAX6,PDGFRA,PTCH1,SOX10" Pubmed 29184203 Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Pubmed 1.17E-07 2.70E-02 5.40E-05 6.98E-04 19 51 "CALB1,CALB2,SLC32A1,HDAC4,DLG4,OLIG2,GPHN,TBR1,GABRA1,GABRG2,GAD1,GAD2,GFAP,PPARGC1A,MYCN,SST,ARHGEF9,TCF4,SLC17A7" Pubmed 17110338 Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Pubmed 1.20E-07 2.75E-02 5.49E-05 7.09E-04 43 191 "ADCY8,AP1B1,APC,ATP2A2,CANX,AIFM1,DCLK1,CFL2,TPP1,CLTA,AKAP6,CEP170,MED12,DPYSL2,EPS8,RACK1,SARAF,SEPT9,KIF3A,IL1RAPL1,ATXN2L,HSPA1L,HSP90AA1,KIF5C,KLC1,IPO5,MAP4,PCMT1,PKD1,PPP2R2B,SEC61A2,RYR3,ERBIN,SEPT3,MMS19,TRIM2,TIAM1,TJP1,TPM3,TRO,UBE3A,XPO1,PCDH15" Pubmed 12074840 "Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology." Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "APP,SV2A,GAD1,GFAP,GRM2,GRM3,MAP2,MAPT,SYP" Pubmed 29056747 PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "SYS1,DLG4,MAP2,PRRT2,SNAP25,STX1A,SYN1,SYN2,SYP" Pubmed 29106906 Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "AQP4,OLIG2,ALDH1L1,GFAP,GLUL,NFIA,NFIX,SLC1A3,SOX2" Pubmed 16701205 A role for Nr-CAM in the patterning of binocular visual pathways. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "CNTN1,EPHB1,CHL1,L1CAM,NRCAM,CNTN3,NFASC,CNTN2,ZIC2" Pubmed 12815021 Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D" Pubmed 24115331 Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "NECTIN3,TUBB3,TBR1,GFAP,MBP,PAX6,RELN,FEZF2,SOX2" Pubmed 15629701 Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "ASCL1,OLIG1,OLIG2,NKX6-2,MBP,PDGFRA,PLP1,DBX2,SOX10" Pubmed 20830809 Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "CNTNAP1,TUBB3,GLUL,COL28A1,NEFH,PRPH,RDX,S100B,SOX10" Pubmed 22318628 Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "CDH2,CTNND1,FOXG1,PRKCZ,SOX2,PCDH15,FZD3,VANGL2,IFT88" Pubmed 8665664 Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation. Pubmed 1.24E-07 2.85E-02 5.58E-05 7.21E-04 9 12 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2C,GRIN2D" Pubmed 18464913 A genome-wide association study identifies protein quantitative trait loci (pQTLs). Pubmed 1.25E-07 2.88E-02 5.63E-05 7.28E-04 21 61 "OSBPL1A,ATP2A2,CACNB2,CNTN1,CHD1L,SACS,DLG2,DOCK2,WDPCP,EPS8,FAM49B,KIRREL3,IL6R,BCO1,PDZRN4,NXPH1,DIRAS2,CYBC1,KHDRBS2,ROBO1,ROBO2" Pubmed 25277244 The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Pubmed 1.32E-07 3.03E-02 5.92E-05 7.65E-04 48 225 "ACTN1,ACTN2,ADD3,ZFAT,ANK1,EIF4G3,ARHGEF7,CLCN3,TJP2,HECTD1,RBM39,GAPVD1,LONRF1,OPTN,KCTD3,EIF4G2,EIF5,EPB41L1,EPB41L2,CEP78,AGAP3,PHYHIPL,INPP5K,NFU1,SPIN1,CBX1,BVES,HSP90AA1,MSL1,RAB41,RBPJ,KLC1,NAP1L1,ENPP2,KANSL1,PSMA6,PPP2R3C,SBF1,CDK5RAP3,SMARCA4,SPATA7,TSNAXIP1,EPB41L3,SUPT5H,OBSL1,TTC3,XPO1,FXR1" Pubmed 22828515 Generation and characterization of Tmeff2 mutant mice. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "GAD1,GAD2,NOS1,RET,SST,TAC1,TMEFF2,UCHL1,SLC17A7,SLC17A6" Pubmed 17462911 STAT5A/B activity is required in the developing forebrain and spinal cord. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CALB2,DLX1,ETV1,TUBB3,TBR1,STMN2,L1CAM,RELN,RORB,CNTN2" Pubmed 23817546 Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "NUMB,CALB2,CDH2,TUBB3,FOXG1,TBR1,PAX6,RELN,SOX2,ZIC1" Pubmed 20058045 Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CALB2,TUBB3,DNER,GFAP,MYO6,MYO7A,PRPH,SLC1A3,SOX2,SYP" Pubmed 22745484 Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CALB1,CALB2,SLC32A1,CDHR1,TBR1,ARX,SYP,UCHL1,SLC17A7,SLC17A6" Pubmed 24262147 Lhx2 regulates a cortex-specific mechanism for barrel formation. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CDH8,LHX2,ETV1,TBR1,GAP43,GRIN1,PAX6,FEZF2,RORB,CUX2" Pubmed 15893981 Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "OLIG2,FABP7,MBP,NKX2-2,PDGFRA,SOX8,SOX1,SOX2,SOX3,SOX10" Pubmed 23197722 Critical role of GFR?1 in the development and function of the main olfactory system. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CALB1,CALB2,TBR1,GAD1,GAD2,GAP43,GFRA1,NCAM1,RELN,SLC17A6" Pubmed 29326173 Transcriptional Regulator ZEB2 Is Essential for Bergmann Glia Development. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "CALB1,ZEB2,OLIG1,GFAP,NTNG2,HES5,MBP,S100B,SOX2,ZIC1" Pubmed 22578469 Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "ASCL1,CALB1,CALB2,FABP7,FGFR1,GAD1,RELN,SOX2,ZIC1,ZIC2" Pubmed 18521945 "Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool." Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "NRP2,CALB2,CDH2,TBR1,GFAP,GRIK4,MSI1,NEUROD1,PROX1,RELN" Pubmed 21122816 Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "SEMA4G,CALB1,OLIG2,SEMA4D,GFAP,PAX6,PLXNB1,PLXNB3,S100B,SEMA4A" Pubmed 14622581 The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2D,RASGRF1,RASGRF2" Pubmed 16790476 Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Pubmed 1.36E-07 3.11E-02 5.92E-05 7.65E-04 10 15 "DCT,OLIG2,FABP7,KIT,MBP,MITF,PLP1,SOX8,SOX10,UCHL1" Pubmed 25515538 A systems-wide screen identifies substrates of the SCF?TrCP ubiquitin ligase. Pubmed 1.36E-07 3.12E-02 5.92E-05 7.65E-04 49 232 "RBM10,ADAR,LRCH2,APC,CACHD1,USP37,APP,BTRC,CDC25B,CLTC,HECTD1,BAG4,ACBD5,CRY2,SIPA1L1,PUM1,DCAF8,MATR3,SMG7,FOXG1,FLNC,KHDRBS3,EML4,DOCK7,USP54,MOV10,MXI1,NACA,NFE2L2,SSH1,PIK3C2A,PTPN13,EML5,USP47,FBXW7,SBF1,FNIP1,SHMT2,AMBRA1,SYBU,SON,WDTC1,TACC1,FBXW11,EIF4ENIF1,ZIC2,TRIM9,SPIRE1,HNRNPA3" Pubmed 21194568 Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Pubmed 1.43E-07 3.29E-02 6.24E-05 8.06E-04 26 88 "ATM,BMPR1B,RUNX1T1,AHCTF1,ZNF521,DLX1,E2F5,E2F6,HEYL,MBNL2,FABP7,FOXM1,NELFCD,GLI2,STMN2,MEIS2,NFIX,PAX6,ANKHD1,DPF2,HES6,ATF7IP,TAF9,NR2E1,TMPO,NSD2" Pubmed 21163940 Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Pubmed 1.48E-07 3.40E-02 6.42E-05 8.30E-04 30 111 "ACTN1,ACTN2,APP,ATP1A1,EVI5L,CLU,PCYT1B,FIS1,ELAVL3,ENO2,ECSIT,TUBA1B,PRAM1,EFEMP1,FGF13,FOXG1,OGA,HMGB1,SCAMP5,FXYD7,PCMT1,RAB3A,SH3GL2,EPN2,EFHD1,MAST1,EPB41L3,NCDN,MPRIP,MLST8" Pubmed 15102471 Bioinformatics and cellular signaling. Pubmed 1.53E-07 3.51E-02 6.62E-05 8.55E-04 40 173 "ACLY,ARHGDIA,ARRB1,ARHGEF7,BTK,CAMK2A,CAMK2B,ARHGEF1,HDAC9,GIT2,ELMO1,DNM2,ABI1,PDCD6IP,DNAJB6,EIF4G2,COPS4,EFS,RTN3,ECSIT,RACK1,SMC2,FYN,GAB1,TRAF3IP2,RAPGEF1,IRAK3,IPO5,PIK3AP1,MEF2C,NAP1L1,NFE2L2,PIK3R1,PRKCZ,MAPK9,PEX5,RYR1,MAPK12,TCF7L2,WIPF1" Pubmed 22681889 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Pubmed 1.56E-07 3.58E-02 6.74E-05 8.72E-04 124 806 "ABCF1,ADAR,ANXA7,API5,CDK13,CCAR2,EIF4G3,FUBP1,PTBP2,CANX,CDK11B,TBRG4,SRSF11,CLTC,QKI,BAG4,ZNF385A,RBM39,CS,CSNK1E,PUM1,MATR3,YTHDC1,MYEF2,ZC3H11A,DDX46,G3BP2,DNM1,CPEB2,RBM12,SUGP2,MBNL2,EIF4G2,EIF5,ELAVL2,EIF1,SRRM1,MRPL10,RACK1,MEX3B,SYNCRIP,NOP56,ZCCHC17,KHDRBS3,CELF1,STAU2,TCERG1,RNPS1,TNRC6A,ZNF638,PRRC2B,NUDT21,DIDO1,PSIP1,ATXN2L,HMGB1,HNRNPK,HSP90AA1,IBA57,IPO5,MAP4,MBNL1,SRSF12,MOV10,MSI1,MYO5A,HNRNPM,NAP1L1,CNOT4,NOVA1,NOVA2,FAM98B,XRN1,PURG,RC3H2,EXOSC10,ANKHD1,FAM120C,RBBP6,RADX,RAVER2,RPL15,ZC3H14,RPS20,NCBP3,SAFB,ATXN2,CASC3,SFPQ,TRA2B,PUF60,CPEB3,MYO18A,DHX30,CPEB4,RBM34,SON,ZCCHC24,PEG10,ZC3H13,RBM26,SRPK2,LARP4,STAU1,ZC3H4,SUPT5H,PRRC2C,PCDHGA9,SYNE1,PUM2,R3HDM1,RBFOX2,ZNF346,UBC,RPL7L1,EIF4ENIF1,UBTF,SF1,PCDH20,CSDE1,FIP1L1,HNRNPA3,FXR1,LAS1L" Pubmed 20029029 Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Pubmed 1.64E-07 3.76E-02 7.07E-05 9.14E-04 25 83 "SPARCL1,CALM1,CBR1,COL9A3,AKAP12,MATR3,RUSC2,EGFR,ERBB2,ERBB4,CEND1,OLFM1,DCTN2,GPM6B,GABARAPL2,HSP90AA1,PPP5C,PRKAR1B,RAB3A,RAP1GDS1,MAST1,CNTN2,TPM1,UCHL1,MAP3K12" Pubmed 16964442 Identification of candidate maternal-effect genes through comparison of multiple microarray data sets. Pubmed 1.68E-07 3.86E-02 7.25E-05 9.37E-04 19 52 "AMPD3,APBB2,RUNX1T1,USP2,BSCL2,IQGAP2,KIT,SMAD1,KITLG,SERPINI1,RGS10,FBXW7,HSPA4L,TRO,ZNF23,NDRG4,NAV2,ST7,SSPN" Pubmed 24595293 "Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration." Pubmed 1.70E-07 3.90E-02 7.27E-05 9.40E-04 12 22 "ETV1,TUBB3,TBR1,MAP2,NEFH,PAX6,RELN,RORB,SATB2,CUX2,TMEM163,SLC17A6" Pubmed 12842915 The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Pubmed 1.70E-07 3.90E-02 7.27E-05 9.40E-04 12 22 "OLIG2,FABP7,FGFR3,GFAP,GLUL,MBP,NKX2-2,PDGFRA,SOX8,S100B,SLC1A3,SOX10" Pubmed 26950368 Diverse functions of myosin VI elucidated by an isoform-specific ?-helix domain. Pubmed 1.70E-07 3.90E-02 7.27E-05 9.40E-04 12 22 "AP2A1,AP2A2,REPS2,COPB2,CLTC,DCTN1,SEC16A,DCTN2,DOCK7,MYO6,PIK3C2A,ARHGEF12" Pubmed 16147992 Analysis of BCL6-interacting proteins by tandem mass spectrometry. Pubmed 1.72E-07 3.96E-02 7.37E-05 9.52E-04 21 62 "OSBPL1A,WDR35,CACNA1A,NCOR1,NCOR2,HDAC9,HDAC4,ARNT2,DNAH9,EBF1,PPARGC1A,ATF7,LPAR4,PCDH9,OLA1,SMARCA4,MAPK8IP3,CSMD1,ZMYND8,EIF4ENIF1,SENP7" Pubmed 28808228 "Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors." Pubmed 1.85E-07 4.24E-02 7.88E-05 1.02E-03 15 34 "AXIN2,APC,NUMB,PROM1,BTRC,CDH2,FABP7,TBR1,GFAP,HES5,AFDN,SOX1,SOX2,SATB2,PARD3" Pubmed 22696295 Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Pubmed 1.98E-07 4.54E-02 8.40E-05 1.09E-03 17 43 "ALCAM,BMP7,SLIT2,CHL1,NR3C1,ATOH8,LAMA2,KITLG,NRCAM,PLCL1,PTCH1,SOX6,ARX,SLIT1,SOX1,TCF12,HEY1" Pubmed 23643363 Chromatin regulation by BAF170 controls cerebral cortical size and thickness. Pubmed 1.98E-07 4.55E-02 8.40E-05 1.09E-03 13 26 "PROM1,ETV1,TUBB3,TBR1,PAX6,POU3F2,RORB,SMARCA4,SMARCC2,SMARCE1,CNTN2,SATB2,CUX2" Pubmed 10087302 Genetic mapping of eight SH3 domain genes on seven mouse chromosomes. Pubmed 1.98E-07 4.55E-02 8.40E-05 1.09E-03 13 26 "BIN1,CACNA1B,CACNB2,SORBS3,SORBS1,GABRA1,HTR2A,DBNL,SH3GL2,SH3GL3,FNDC3A,SYT4,VAV2" Pubmed 14973295 Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Pubmed 2.00E-07 4.60E-02 8.47E-05 1.09E-03 14 30 "SYT13,PTCH2,INA,DLX1,EBF1,GAP43,MSTN,GLI2,SHISAL1,MAPT,NELL2,PTCH1,SLC1A2,SYT4" Pubmed 19838179 Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Pubmed 2.00E-07 4.60E-02 8.47E-05 1.09E-03 14 30 "ZEB2,ELAVL3,ELAVL4,OLIG2,FABP7,FGFR3,TBR1,GFAP,NTRK3,POU3F2,MAPK3,MAPK8,SOX5,SATB2" Pubmed 18391951 Many sequence variants affecting diversity of adult human height. Pubmed 2.07E-07 4.75E-02 8.73E-05 1.13E-03 35 143 "HACE1,LCORL,NOG,ZBTB24,DDX46,SV2A,DTNB,DNAJC27,PRAM1,EFEMP1,STRADA,CAP2,SPIN1,BVES,MRPL42,SLCO1C1,PDE3A,PENK,SERPINI1,RASGEF1B,BCAS3,PEX2,RBBP8,ZFHX4,RPS20,SH3GL3,KIF13A,ADAMTS17,POPDC3,HHIP,CDK20,PPIL6,ZBTB38,ADAMTSL3,ADAMTS10" Pubmed 16168404 Gli3 is required for the specification and differentiation of preplate neurons. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "AXIN2,NUMB,CALB2,TBR1,STMN2,MAP2,PAX6,RELN,SOX2,TJP1,PARD3" Pubmed 12130536 Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "CDK5R1,OLIG1,ETV1,FABP7,TBR1,GAD1,POU3F2,POU3F4,RELN,RORB,VLDLR" Pubmed 23791195 "mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking." Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "PPFIA2,PPFIA1,CASK,BSN,ERC2,DLG4,LRRC4B,NLGN1,ERC1,STXBP1,SLC17A7" Pubmed 19217427 AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "APC,OLIG2,FABP7,TUBB3,GFAP,MAP2,MBP,PRKAB2,PRKCZ,SOX2,PARD3" Pubmed 23946445 Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "EMX2,TUBB3,FGFR3,RBPJ,HES5,MYO6,MYO7A,PROX1,SOX2,HEY1,HEY2" Pubmed 23895693 Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "ETV1,TUBB3,TBR1,ALDH1L1,GFAP,GLUL,PAX6,POU3F2,S100B,SATB2,DICER1" Pubmed 22405202 A radial glia-specific role of RhoA in double cortex formation. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "MRTFA,TUBB3,TBR1,GFAP,MAG,MDGA1,PAX6,FEZF2,RORB,SATB2,PARD3" Pubmed 16920270 Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "ETV1,FABP7,TUBB3,FOXG1,TBR1,GFAP,MAP2,PAX6,RELN,FEZF2,CUX2" Pubmed 21421818 Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "HDAC9,HDAC4,MEF2C,MYH7,NPPA,PPP3CA,PPP3CB,MAPK3,RPS6KA2,TRPC1,TRPC3" Pubmed 20685999 A novel transient glutamatergic population migrating from the pallial-subpallial boundary contributes to neocortical development. Pubmed 2.49E-07 5.71E-02 1.03E-04 1.33E-03 11 19 "ASCL1,CALB1,OLIG2,ETV1,TBR1,GFAP,MAPT,PAX6,RELN,CUX2,SLC17A6" Pubmed 14759258 An unappreciated role for RNA surveillance. Pubmed 2.67E-07 6.13E-02 1.10E-04 1.43E-03 28 102 "CHRD,ATP1A1,CFLAR,CD38,ZFYVE9,PPT2,DMPK,DTNB,USH1C,CELF1,GABBR1,GFRA1,GLS,KCNQ2,MAN2A2,MAP2,MAP4,ADAM11,ADAM22,MSR1,NPR2,SETD4,PDE4A,PTPRD,RAD51D,IL17RB,SH3BP2,SON" Pubmed 15057823 The DNA sequence and analysis of human chromosome 13. Pubmed 2.69E-07 6.19E-02 1.11E-04 1.44E-03 39 170 "SLITRK1,RCBTB2,SLITRK5,DCT,SACS,FRY,MBNL2,LPAR6,PAN3,KATNAL1,FGF14,UFM1,ATP8A2,WASF3,PCDH17,GPR12,SERP2,KLF12,HTR2A,LIG4,HS6ST3,CHAMP1,PCDH9,DCUN1D2,AMER2,SUPT20H,FNDC3A,MYCBP2,ZC3H13,RBM26,SPART,THSD1,ATP11A,DOCK9,ZIC2,UPF3A,CAB39L,ZDHHC20,SPATA13" Pubmed 20562862 A mouse knockout library for secreted and transmembrane proteins. Pubmed 2.75E-07 6.31E-02 1.13E-04 1.46E-03 73 411 "SLC25A25,SLITRK1,KIAA1324,C1QTNF1,C1QTNF3,FAM131A,LRRC4C,TMEM108,CADM3,PNKD,BOC,MYADM,INTS1,TMEM130,LYPD1,NTM,SEZ6L2,SIDT2,STARD3NL,HSD17B14,ENPP6,TLR7,CD320,FAM198B,TMEM107,DKK3,ERAP1,SIGLEC8,MALT1,KIRREL3,DHRS4,LNX1,ADGRA3,CNDP1,CACFD1,MFSD2A,LINGO1,WIF1,SCRG1,LRRTM3,LRRTM1,OLFM3,IL17D,LAYN,NNAT,CYTL1,SMOX,TRHDE,DRAM2,LRRN3,SUSD4,STK32B,DRAXIN,SCN2B,LRRTM4,NTNG1,GLT8D1,IZUMO4,THSD1,TAC3,VWC2,LRRC8A,SEZ6L,TRPM2,TMEFF2,FLRT2,FLRT1,LYPD6,TMEM178A,SIGLEC10,RSPRY1,PIANP,NETO2" Pubmed 15964765 Differential expression of individual gamma-protocadherins during mouse brain development. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "PCDHGB4,CDH2,PCDHGC3,PCDHGC5,PCDHGB6,PCDHGA4,PCDHGA3,PCDHGA1" Pubmed 24243579 SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "APC,CALB1,ZEB2,TBR1,GFAP,GRM2,NEFH,SOX2" Pubmed 29536590 Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "TUBB3,GAP43,MYO6,MYO7A,NEFH,NRCAM,SOX2,SYT1" Pubmed 8901523 Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "CALM1,SYT6,NRXN1,SYT9,RPH3A,SYT1,SYT4,SYT5" Pubmed 16540585 Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "CALB1,CALB2,TBR1,NEFH,PAX6,POU3F2,RELN,SLC17A6" Pubmed 23606270 Spatiotemporal expression of Zic genes during vertebrate inner ear development. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "AXIN2,ZIC4,ZIC5,POU3F4,SOX10,ZIC1,ZIC2,ZIC3" Pubmed 9069281 Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Pubmed 2.88E-07 6.61E-02 1.17E-04 1.52E-03 8 10 "GABBR1,GABRA1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Pubmed 15172686 Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. Pubmed 2.93E-07 6.73E-02 1.19E-04 1.54E-03 17 44 "C1QTNF3,ALCAM,CAPRIN2,SLC22A6,FAM19A5,CRYM,TENM4,SNAP91,SPSB4,GCNT2,RABL2A,PCDH9,RAVER2,SALL1,CLSTN1,SMARCD3,SOX11" Pubmed 19389623 Docking motif-guided mapping of the interactome of protein phosphatase-1. Pubmed 3.12E-07 7.18E-02 1.27E-04 1.64E-03 24 80 "ELFN2,SLC7A14,DZIP3,SPATA2,SACS,DLG2,DLG3,TMEM132C,PCDH11X,GPR12,KCNK10,HYDIN,SYTL2,CSRNP3,PREX2,TMEM132D,RBM26,RPGRIP1L,RIMBP2,CSMD1,TSC2,ELFN1,ZBTB38,WNK1" Pubmed 20016102 The small GTPase Rac1 regulates auditory hair cell morphogenesis. Pubmed 3.23E-07 7.43E-02 1.30E-04 1.68E-03 12 23 "WHRN,USH1C,FOXG1,MYO6,MYO7A,PAK3,SPTAN1,TUBB2A,TUBB1,TUBA1A,FZD3,VANGL2" Pubmed 9225980 cDNAs with long CAG trinucleotide repeats from human brain. Pubmed 3.23E-07 7.43E-02 1.30E-04 1.68E-03 12 23 "EP400,CASK,MAGI1,NUMBL,NCOR2,MED12,TOX3,TNRC6A,CELF3,ATXN2,ZNF384,JPH3" Pubmed 24487590 TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. Pubmed 3.23E-07 7.43E-02 1.30E-04 1.68E-03 12 23 "CALB1,CALB2,HAP1,GAD1,GFAP,GNG4,KCNJ4,KITLG,PAX6,RELN,SYBU,ARC" Pubmed 22988430 A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Pubmed 3.23E-07 7.43E-02 1.30E-04 1.68E-03 12 23 "ACHE,NDRG2,TACC2,LMO1,SATB1,SOX2,SOX10,KIF1B,UCHL1,TRIM9,NDRG4,RTN4" Pubmed 19838178 The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "OLIG1,OLIG2,GFAP,GPR17,MAG,MBP,NEFH,PDGFRA,PLP1,UGT8" Pubmed 28685891 Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "ASCL1,DLX1,GAD1,NKX2-2,NPY,PENK,ARX,SOX2,TAL1,SLC17A6" Pubmed 24142862 Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "CDK5R1,CALB1,CALB2,EGFR,ERBB2,ERBB4,TUBB3,NRG3,GAD1,SST" Pubmed 27779093 MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "PCDH19,PCDH10,NRXN1,GABRA5,PCDH17,MEF2C,NOS1,NTNG1,NLGN1,SHANK2" Pubmed 21466690 Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "CALB1,CALB2,ELAVL3,ELAVL4,TBR1,GAD1,GAD2,PAX6,SLC17A7,SLC17A6" Pubmed 19549840 Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "ASCL1,CALB1,DLX1,OLIG2,TUBB3,PPP1R1B,TBR1,NPY,PDPK1,SLC17A7" Pubmed 24441682 Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "CDH8,ETV1,PPP1R1B,TBR1,GAD1,MEF2C,MDGA1,RORB,NTNG1,CNTN2" Pubmed 27320921 Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "TBR1,INSM1,L1CAM,NEUROD1,PAX6,RELN,SOX2,CNTN2,SATB2,ZFPM2" Pubmed 16854408 The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "ALCAM,SLIT2,EPHB1,L1CAM,NKX2-2,ROBO1,ROBO2,SLIT1,ROBO3,CNTN2" Pubmed 26389685 Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "CALB1,SLC32A1,CNTNAP2,PPP1R1B,GAD1,MAG,PENK,CNTNAP3,TAC1,SLC17A7" Pubmed 20554876 MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "OLIG1,OLIG2,GFAP,NKX2-2,PAX6,PDGFRA,S100B,SLIT1,SOX10,DICER1" Pubmed 21300049 Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "HEYL,EMX2,TUBB3,HES5,MYO6,MYO7A,PROX1,SOX2,HEY1,HEY2" Pubmed 28066179 "Distinct and Cooperative Functions for the Protocadherin-?, -? and -? Clusters in Neuronal Survival and Axon Targeting." Pubmed 3.30E-07 7.58E-02 1.30E-04 1.68E-03 10 16 "CALB1,CALB2,SLC32A1,TUBB3,GFAP,MAP2,PCDHB15,PCDHB4,SLC17A7,SLC17A6" Pubmed 19460752 A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. Pubmed 3.32E-07 7.63E-02 1.31E-04 1.69E-03 46 218 "NDRG3,ADD2,ARNTL,MYOM1,RGS11,NRP2,CDK5R2,CAPN3,NPIPA1,NRXN1,FAM149A,KIAA0408,DTNA,TSPAN5,EPB41,TUBA1B,ACTL6B,FOXO3,AFF2,TPK1,GALC,RAPGEF6,TUBA1C,PRDM5,HSD17B1,SMAP1,IL6ST,CDK18,PKD1,SNX10,PROX1,OCIAD1,RGS4,RIC8B,SH3BGR,CXXC4,TAB2,FAM208A,WSCD1,ACSL6,TCF12,DICER1,AMOT,PMEPA1,PRDM2,TUBA1A" Pubmed 20308569 Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Pubmed 3.32E-07 7.64E-02 1.31E-04 1.69E-03 14 31 "AXIN2,NRP2,CALB2,ETV1,TBR1,GRIK4,WIF1,SMAD1,SMAD9,MEF2C,MAPK3,PROX1,SOX5,CUX2" Pubmed 26354767 Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Pubmed 3.40E-07 7.82E-02 1.34E-04 1.73E-03 31 121 "AP2A1,DDO,LINC00173,OSGIN2,TJP2,NECTIN3,NCOR1,CYBB,CTIF,ALKBH8,PHF20L1,KATNAL1,TUBA1B,DLC1,CINP,DIDO1,GRIK3,GRM3,LRRTM1,ITGAV,CDK18,SPDL1,PTPRN2,FBXW7,TNFRSF19,PUF60,RALYL,C5orf64,NELFE,RSPRY1,SENP7" Pubmed 22056141 Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions. Pubmed 3.48E-07 7.99E-02 1.36E-04 1.76E-03 13 27 "CALB2,OLIG2,TUBB3,TBR1,GFAP,MBP,PAX6,MAPK3,S100B,SLC1A3,TSC1,TSC2,RICTOR" Pubmed 15917450 Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. Pubmed 3.48E-07 7.99E-02 1.36E-04 1.76E-03 13 27 "LHX2,DLX1,EBF1,EFNA2,EMX2,EN2,EPHB1,FOXG1,GBX2,PAX6,PROX1,TCF4,TCF7L2" Pubmed 11891216 "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs." Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "PICK1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRM2,GRM3,GRM7" Pubmed 23727838 "A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse." Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "ASCL1,CALB2,NECTIN3,TUBB3,TBR1,GAD1,TUBB2B,FEZF2,RORB" Pubmed 15145078 Quantification of synapse formation and maintenance in vivo in the absence of synaptic release. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "DOC2A,DLG4,GRIA2,MAPT,STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 23142661 Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "SLC12A5,CALB2,ETV1,GAD1,NOS1,NPY,SATB1,SST,CUX2" Pubmed 26637354 Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "OLIG1,DPYSL2,OLIG2,TUBB3,GFAP,MAG,MBP,NKX2-2,SOX10" Pubmed 21460838 Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "CALB1,CALB2,EFNB3,TBR1,GFAP,RELN,SATB2,VLDLR,LRP8" Pubmed 26813976 Gradient COUP-TFI Expression Is Required for Functional Organization of the Hippocampal Septo-Temporal Longitudinal Axis. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "NRP2,CALB1,CALB2,CDH8,GAD1,GRIK4,MAP2,NEFH,FEZF2" Pubmed 16452088 O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry. Pubmed 3.68E-07 8.44E-02 1.42E-04 1.83E-03 9 13 "BSN,CTNND2,SORBS1,PCLO,TPPP,SYNPO,SHANK2,SYN1,EMSY" Pubmed 16382104 International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pubmed 3.73E-07 8.57E-02 1.43E-04 1.85E-03 16 40 "KCNH8,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNQ2,KCNQ3" Pubmed 20381070 Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Pubmed 3.73E-07 8.57E-02 1.43E-04 1.85E-03 16 40 "CPNE2,ARHGDIA,SCRN1,DPYSL2,ENO2,TUBA1B,NEFM,RNH1,SNCA,SPTAN1,TPM1,TPM2,TPM3,TPM4,TUBB2A,UCHL1" Pubmed 20734064 A large-scale candidate gene association study of age at menarche and age at natural menopause. Pubmed 3.92E-07 8.99E-02 1.50E-04 1.94E-03 54 275 "ADRB2,AGT,AMH,ARRB2,BMP7,BMPR1B,CCK,SCARB1,NOG,CHRNA4,CHRNB2,CNR1,FGFR1OP2,DRD1,EML1,F5,FGFR1,AFF2,DOT1L,GDF1,MSTN,GDF9,GHR,MCHR1,ADAMTS13,NR3C1,SLC2A6,HSD17B1,HTR2A,HTR5A,IGF1,IGFBP1,SMAD1,MAOB,NODAL,NPY,PCSK1,PDYN,PENK,FTO,PLIN1,POLG,PTH1R,DOK5,SST,SSTR1,SSTR2,NEK4,ABCC8,TACC1,LEFTY2,TGFBR3,FMN2,ADAMTS9" Pubmed 17015433 Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Pubmed 4.00E-07 9.20E-02 1.53E-04 1.98E-03 50 247 "ARID1A,TMCC3,MTUS1,PLA2G6,ALS2,SHTN1,THSD7A,PLAA,FAM189A2,AKAP7,RCHY1,CENPL,WDR20,DNAJB6,DNM1L,STARD3NL,POLK,ERGIC3,MTHFD2,GART,COPS8,SPIN1,OS9,GPR19,ICA1,NKD1,NPTX2,ODF2,EXOSC10,PPP5C,LRRC49,SYTL2,SPDL1,RDX,DCUN1D2,SGSM1,CCDC112,TRA2B,EPC1,ZBTB43,RBM26,PDLIM2,MTMR14,WBP2,TRPS1,UBC,CCDC14,NAV2,FAM47E,NELFE" Pubmed 25332235 Substrate trapping proteomics reveals targets of the ?TrCP2/FBXW11 ubiquitin ligase. Pubmed 4.04E-07 9.28E-02 1.55E-04 2.00E-03 32 128 "AXIN2,OGT,EPB41L5,CACHD1,USP37,BTRC,CDC25B,MAGI1,CBARP,CLTC,ACBD5,COPS7A,MTSS1L,FLNC,TUBGCP4,USP54,NFE2L2,NRDC,PLEC,PTPN13,EML5,USP47,KCTD17,FNIP1,MAGI3,ELMO2,TACC1,FBXW11,TIAM1,TJP1,UBC,TRIM9" Pubmed 25917818 Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Pubmed 4.27E-07 9.80E-02 1.63E-04 2.10E-03 21 65 "AXIN2,ANK1,HCN2,CACNA1A,TPP1,CNTN1,EFNB3,FGFR1,ATP8A2,MYO5A,MYO7A,OPHN1,RORB,SCN8A,SOX10,ROBO3,UCHL1,WNT7A,PLD4,VANGL2,AP3B2" Pubmed 21731673 Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Pubmed 4.28E-07 9.83E-02 1.63E-04 2.11E-03 68 378 "ACADM,FZD9,NR0B1,USP28,PTCH2,NCOA1,ATP1B3,ADAM23,BBS2,BCL2L2,BMPR1B,MTMR7,AIFM1,JAM2,LHX2,ANKRD35,ZNF385A,UBXN2A,HDAC9,HDAC4,FBXL5,PARD6A,FGF1,FGFR1,FGFR3,NKX6-2,GBX2,GDF9,NFU1,GLI2,GPR19,PRDM5,ZBTB45,RBPJ,KIT,SMAD1,NCAM1,RCOR2,NEUROD1,NKX2-2,NODAL,PAX6,PFKP,NOMO2,PIK3CD,PIK3R1,PTCH1,RFX4,SALL1,SGK1,SLC6A1,SOX1,SOX2,SOX11,SOX15,SPP1,KDM4C,TCF4,TRIM2,DICER1,LEFTY2,TGFBR3,ZKSCAN5,WNT7A,ZIC3,SMARCAD1,FZD3,KAT6A" Pubmed 22926577 "Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis." Pubmed 4.28E-07 9.84E-02 1.63E-04 2.11E-03 17 45 "NDRG2,DYNLL1,CALM1,INA,SYNGR3,CDC42,SEC16A,TTBK1,PADI2,MAG,MAOB,MBP,PLP1,MAPKAP1,ZNF430,SIRT2,CCDC14" Pubmed 20677014 An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Pubmed 4.44E-07 1.02E-01 1.68E-04 2.18E-03 42 193 "ABAT,SYN3,ASIC2,ADCY8,SORCS1,DOC2A,APBB2,ADGRB2,ADGRB3,BMP7,CACNB2,SCARB1,CHRNB2,AKAP6,TRIM69,DGKB,DAPK1,DCC,DRD1,HIPK3,EPS8,FOXO3,GAB1,NEK6,PPARGC1A,ADGRA3,PCLO,PARD3B,RFFL,KCNMA1,MDM4,GIT1,PLCB2,SCP2,ELMOD1,NLGN1,WDR37,SNAP25,ADGRL3,TRPC3,TRPS1,CADM1" Pubmed 17979178 A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes. Pubmed 4.45E-07 1.02E-01 1.69E-04 2.18E-03 25 87 "SHROOM2,KSR1,OSBPL3,HDAC4,DENND4A,BAIAP2,FOXO3,RASSF8,KLC1,MARK3,AFDN,CDK18,PFKFB2,KIF1B,CLASP2,CLASP1,CRTC1,TIAM1,PARD3,TP53BP2,TSC1,TSC2,KLC2,REEP1,TUBA1A" Pubmed 18498735 Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Pubmed 4.59E-07 1.05E-01 1.74E-04 2.24E-03 15 36 "MRTFA,LDB2,ETV1,TUBB3,GFRA1,GFRA2,NCAM1,NEFH,NTRK2,NTRK3,PRPH,RET,TAC1,TRPC3,UCHL1" Pubmed 23312517 Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Pubmed 5.04E-07 1.16E-01 1.90E-04 2.45E-03 11 20 "ASCL1,NRP2,CALB2,DCC,ZEB2,ERBB4,GAD1,NPY,UNC5B,SST,FLRT2" Pubmed 29170629 Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool. Pubmed 5.04E-07 1.16E-01 1.90E-04 2.45E-03 11 20 "CDH2,ELAVL3,ELAVL4,GAD1,MAP2,MAPK3,MAPK9,RFX3,SOX2,TJP1,SLC17A6" Pubmed 17460091 "Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation." Pubmed 5.04E-07 1.16E-01 1.90E-04 2.45E-03 11 20 "ASCL1,CALB1,CALB2,EBF1,ETV1,PPP1R1B,GAD1,MAP2,NPY,PENK,ARX" Pubmed 25888505 Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Pubmed 5.04E-07 1.16E-01 1.90E-04 2.45E-03 11 20 "ASCL1,CALB1,OLIG2,FABP7,GFAP,PAX6,SOX8,S100B,SLC1A3,SOX2,SOX10" Pubmed 21697133 Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. Pubmed 5.13E-07 1.18E-01 1.93E-04 2.49E-03 30 117 "ADD2,KIDINS220,DISP3,PDXK,ARHGDIG,CADPS,KIF1A,VAX2,ZNF385A,SEC16A,FAM57B,FAM78B,CDHR1,HHIPL1,CPLX1,SRCAP,GOLGB1,HMX1,DPP10-AS1,MATK,AFDN,BLOC1S2,RCOR2,NEUROD1,NUMA1,PAX6,RXRG,SLC1A7,MAPK8IP3,JPH3" Pubmed 20467437 Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. Pubmed 5.23E-07 1.20E-01 1.96E-04 2.53E-03 94 581 "RBM10,ARID1A,AP1B1,TAOK1,PPFIA1,MAGEE2,API5,ATM,BID,BLM,FUBP1,PTBP2,HIP1R,MAP7,ARHGEF1,ARHGEF2,SEPT7,CDC27,LRWD1,COPB2,SRSF11,NIPBL,CHD1L,SEC31B,RBM39,NCOR2,SEC24C,CTNND1,INTS1,DCTN1,GSDME,DDX46,G3BP2,DNM2,DOCK2,PDCD6IP,DNM1L,SRRM1,TUBA1B,TUBB3,MED12L,SEC23B,SYNCRIP,DCTN2,SMC2,STAG2,SEPT9,TUBGCP4,ARFIP1,BRD8,ZNF638,GNAS,GOLGB1,NUDT21,TUBA1C,DDX19B,HNRNPK,HSP90AA1,IPO5,LIMS1,MPP2,HNRNPM,NF1,OLA1,PFKP,ANLN,PLEC,EXOSC10,KANSL1,PKN2,PSMD13,FAM120C,SFPQ,KIF27,PUF60,SCAF8,KIF21A,FERMT1,SMARCA4,SMARCC2,SPTAN1,EPB41L3,MTCL1,EXOC7,CLASP1,TMPO,METTL3,TUBB1,SMARCAD1,INTS3,FIP1L1,DOCK8,HNRNPA3,LAS1L" Pubmed 19851296 Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Pubmed 5.33E-07 1.22E-01 1.99E-04 2.58E-03 34 142 "SORCS2,BIN1,GAS7,USP37,SPTBN4,SLIT2,AKAP12,NCOR2,DNAJC6,RABGAP1L,TRAPPC9,ATL1,FAM13A,MEGF11,SEPT9,ACSS1,CPLX2,ALDH1L1,DIDO1,ACOT7,PCSK2,MAPKAP1,PIGG,PTPRN2,RGS12,SBF1,ZFP30,WDR37,OGDHL,CAMTA1,VIPR2,ITM2C,WNK2,JPH3" Pubmed 19948975 Integrative predictive model of coronary artery calcification in atherosclerosis. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 47 229 "SORCS1,ADORA2A,ADRB2,AGT,AMPD2,APOC2,RGS9,C5,CBS,SCARB1,ABCG1,CTH,NOS1AP,DMPK,EDN1,FEM1B,PLEKHA1,ELN,MRPL10,TLR7,F5,EFEMP1,PRKAG2,GCK,PPARGC1A,GNAS,GRK4,NR3C1,HMGCR,IGF1,IGFBP1,KCNK1,KCNK2,MTR,MYO7A,NFE2L2,NPPA,OLR1,PAX6,PDE4D,PDYN,PLTP,PPARA,PRKAB2,TCF7L2,TLR4,WRN" Pubmed 10920050 Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "CALB1,CALB2,CCK,TUBB3,MAP2,NPY,SST" Pubmed 11526078 Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "OLIG1,OLIG2,GFAP,MBP,NKX2-2,PDGFRA,PLP1" Pubmed 17131403 "Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development." Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "CNTN1,GAP43,L1CAM,MAP2,MAPT,FAT3,CNTN2" Pubmed 22912413 Slit2 and Robo3 modulate the migration of GnRH-secreting neurons. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SLIT2,TUBB3,PRPH,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 12837627 Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "OLIG1,OLIG2,GLI2,MBP,NKX2-2,PDGFRA,PLP1" Pubmed 25047565 Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "PICK1,GRIK2,GRM1,GRM7,SST,ELFN1,SLC17A7" Pubmed 18615557 Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "CADM3,FABP7,GAD1,CADM1,CADM2,SLC17A7,SLC17A6" Pubmed 15071120 Molecular determinants of synapsin targeting to presynaptic terminals. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SYN3,DLG4,GAP43,SYN1,SYN2,SYP,SYT1" Pubmed 26345464 Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "APC,OLIG2,MBP,PDGFRA,SOX6,SOX5,SOX10" Pubmed 658175 Studies of erythrocyte protoporphyrin in anemic mutant mice: use of a modified hematofluorometer for the detection of heterozygotes for hemolytic disease. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "ANK1,HEPH,KIT,KITLG,SLC11A2,CDK5RAP2,SPTB" Pubmed 22349628 Multiple Slits regulate the development of midline glial populations and the corpus callosum. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SLIT2,GAP43,GFAP,ROBO1,ROBO2,SLC1A3,SLIT1" Pubmed 20631173 Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SLIT2,L1CAM,ROBO1,ROBO2,SLIT1,ROBO3,CNTN2" Pubmed 27294512 "Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair." Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "ZEB2,EDNRB,TUBB3,MBP,S100B,SOX2,HEY2" Pubmed 12115694 Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "BSN,CALB1,SLC32A1,DLG4,DMD,STX1A,SYP" Pubmed 25754822 Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "OLIG2,GFAP,MBP,PDGFRA,PLP1,SLC1A3,DAAM2" Pubmed 15681343 Control of excitatory and inhibitory synapse formation by neuroligins. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SLC32A1,DLG4,GRIA1,GRIN1,NLGN3,NLGN1,SLC17A7" Pubmed 12895513 Development of the mouse neuromuscular junction in the absence of regulated secretion. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SYN3,ACHE,GAP43,NEFH,STXBP1,SYN1,SYN2" Pubmed 20798046 Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "CALB2,FOXG1,HES5,MYO7A,SLC1A3,SOX2,HEY1" Pubmed 14532115 "Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold." Pubmed 5.81E-07 1.33E-01 2.11E-04 2.72E-03 7 8 "SLC12A5,SLC12A6,GFAP,KCNJ10,MAG,MAP2,SYP" Pubmed 24983448 FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. Pubmed 5.90E-07 1.35E-01 2.13E-04 2.75E-03 12 24 "CALB1,CALB2,FABP7,FGFR1,FGFR3,GAD2,GFAP,PAX6,PTCH1,S100B,SLC1A3,SOX2" Pubmed 16637659 Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays. Pubmed 5.90E-07 1.35E-01 2.13E-04 2.75E-03 12 24 "CASK,DLG2,DLG3,DLG4,CACNG2,KCNA4,PAX6,RGS3,MAPK12,CNKSR2,KIF1B,TJP1" Pubmed 26620267 Impaired Interneuron Development after Foxg1 Disruption. Pubmed 5.91E-07 1.36E-01 2.13E-04 2.75E-03 13 28 "ASCL1,NRP2,CALB1,CALB2,DLX1,EPHB1,FOXG1,GAD1,PROX1,RELN,ROBO1,SLIT1,SST" Pubmed 22991444 Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres. Pubmed 5.91E-07 1.36E-01 2.13E-04 2.75E-03 13 28 "ASCL1,DLX1,ELAVL3,FOXG1,GAD1,GBX2,NKX2-2,NPY,PENK,ARX,SOX2,TAL1,SLC17A6" Pubmed 25336744 The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Pubmed 5.91E-07 1.36E-01 2.13E-04 2.75E-03 13 28 "AXIN2,CALB2,SLIT2,DCC,TBR1,GFAP,L1CAM,NFIA,ROBO1,DRAXIN,SOX2,SATB2,ZIC2" Pubmed 15174051 "An investigation into the human serum ""interactome""." Pubmed 6.04E-07 1.39E-01 2.17E-04 2.80E-03 37 162 "ADRA1B,AMPD3,APOC1,APOC2,IGDCC4,ATM,C1QC,AP1M1,CACNA1I,CLU,CP,CST3,FAM169A,DGKG,DCC,SACS,DMD,SORBS3,GABBR1,GFAP,GSN,PTPN5,HBA1,HP,KCNMA1,MIA2,PDE4B,PDZRN4,QDPR,ROBO3,CAMTA1,OBSL1,DICER1,CRB1,AP4E1,TIAM1,GJC2" Pubmed 20096683 A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Pubmed 6.18E-07 1.42E-01 2.22E-04 2.86E-03 17 46 "ADORA2A,GUCD1,DLX1,ERBB4,ETV1,TUBB3,TBR1,GAD1,GGT5,GSTT2,LSS,PAX6,S100B,ARX,SST,DIP2A,CABIN1" Pubmed 20198315 Association of genetic variants with hemorrhagic stroke in Japanese individuals. Pubmed 6.34E-07 1.46E-01 2.27E-04 2.93E-03 34 143 "SORCS2,BIN1,GAS7,USP37,SPTBN4,SLIT2,AKAP12,NCOR2,DNAJC6,RABGAP1L,TRAPPC9,ATL1,FAM13A,MEGF11,SEPT9,ACSS1,CPLX2,ALDH1L1,DIDO1,ACOT7,PCSK2,MAPKAP1,PIGG,PTPRN2,RGS12,SBF1,ZFP30,WDR37,OGDHL,CAMTA1,VIPR2,ITM2C,WNK2,JPH3" Pubmed 21044950 Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. Pubmed 6.40E-07 1.47E-01 2.29E-04 2.96E-03 61 330 "CPNE2,AMPD2,AMPH,PHYHD1,PRX,MADD,ARHGDIA,ARRB1,MAP7,SULT4A1,CRYBB1,CRYM,FAM131B,DBN1,EEF1D,ENO2,EPB41L1,PIPOX,RTN3,TUBB3,EVL,TRIM16,ARPP21,PTPN5,PACSIN2,DDX19B,ACOT7,HMGB1,HNMT,HNRNPK,LRRC25,IPO5,MAP4,DBNL,MT3,NAP1L1,NASP,NUMA1,PALM,PDE1B,PFKP,PKM,PACSIN1,TNPO2,PRKCB,PEX5,RGS3,KCTD17,MAPK12,SARS,SH3GL2,SMARCC2,NCDN,SUPT5H,PDLIM2,TBL1X,TUBB2A,UCHL1,XPO1,RGMA,RTN4" Pubmed 26743624 Pulmonary neuroendocrine cells function as airway sensors to control lung immune response. Pubmed 7.02E-07 1.61E-01 2.51E-04 3.24E-03 15 37 "ASCL1,CALB1,CCK,CHGA,SLIT2,EDN1,TUBB3,GAD1,PENK,ROBO1,ROBO2,SLIT1,SST,SYP,TAC1" Pubmed 20410112 Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "CALB1,CALB2,TUBB3,FGFR1,TBR1,GAD1,PAX6,RELN,SST,SATB2" Pubmed 26802325 Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "PROM1,CDH2,CTNND1,TBR1,RELN,SOX2,CRB1,TJP1,PARD3,CRB2" Pubmed 10357937 Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "ACHE,CHGB,GAP43,NR3C1,L1CAM,NPY,PENK,PRPH,SST,SCG2" Pubmed 25116473 Fgfr1 inactivation in the mouse telencephalon results in impaired maturation of interneurons expressing parvalbumin. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "APC,ASCL1,DLG4,FGFR1,TBR1,GAD1,GFAP,KCNC1,SLC1A3,SST" Pubmed 27725084 Calcium handling precedes cardiac differentiation to initiate the first heartbeat. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "ACTN2,ATP2A2,MYOM1,CACNA1G,CACNA1D,MEF2C,MYH6,SLC8A1,SOX1,MESP1" Pubmed 28272472 Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "ETV1,TBR1,CLDN11,PAX6,RELN,RORB,SLC1A3,SOX2,SATB2,CUX2" Pubmed 23444355 Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "ASCL1,EBF1,OLIG2,FOXG1,NPY,PAX6,SOX1,SOX2,SOX3,SST" Pubmed 22095278 RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "ETV1,FABP7,TBR1,GFAP,MAP2,RELN,RORB,SLC1A3,SATB2,CUX2" Pubmed 21957238 Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "DLG4,ELAVL3,ELAVL4,TUBB3,SMAD1,SMAD9,NTRK3,S100B,SNAP25,UCHL1" Pubmed 15570159 "CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity." Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "L1CAM,RELN,CNTN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 19666823 "MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex." Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "PROM1,CDH2,FABP7,TBR1,PAX6,PRKCZ,RELN,SLC1A3,SOX2,PARD3" Pubmed 23197712 Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "NUMB,NUMBL,GLUL,RBPJ,HES5,PAX6,PRKCZ,HEY1,TJP1,PARD3" Pubmed 26727548 Adult mouse cortical cell taxonomy revealed by single cell transcriptomics. Pubmed 7.31E-07 1.68E-01 2.56E-04 3.30E-03 10 17 "CALB2,SLC32A1,GAD2,NOS1,RORB,SNAP25,SST,TAC1,CUX2,SLC17A6" Pubmed 20439489 "miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells." Pubmed 7.35E-07 1.69E-01 2.57E-04 3.32E-03 31 125 "WDR35,ADAM23,NRP2,CACNB4,INA,LRBA,STOML1,UBXN2A,CTH,SPOCK2,ELAVL2,PCOLCE2,EPS8,GLDC,PRDM5,GSTT2,PADI2,MAT2A,NEFH,PAX6,PFKP,SNX10,RFX2,MRAS,SOX1,KDM3A,SPP1,SSTR1,TRIM2,SIRT1,UBTF" Pubmed 25910212 Widespread macromolecular interaction perturbations in human genetic disorders. Pubmed 8.15E-07 1.87E-01 2.84E-04 3.67E-03 78 461 "ACTN1,ACTN2,NR0B1,GPRASP2,AMPD3,AQP4,ASPA,BTK,CA8,CACNB4,LURAP1,TRIM41,KRIT1,ZBED1,CFL2,CHN1,FBXO7,HOMER3,FHL5,MAGED1,PNKD,CRYBB1,CSNK1E,PDE4DIP,KATNAL2,ACY3,JAKMIP2,DMD,EBF1,OPTN,RBM12,SH3GLB1,GOLGA7,IRAK4,HSD17B14,MRPL10,EFEMP1,RACK1,FDFT1,AMOTL2,CAP2,KHDRBS3,PNMA2,AHCYL1,MYOZ2,GFAP,GGT7,GLUL,LNX1,ZNF496,C1orf94,HSF2,LIG4,MDFI,KCTD6,MID1,NCF2,PMP22,C19orf57,GRAMD1C,SPDL1,RAD51D,KHDRBS2,RXRG,CDK5RAP3,SPP1,STXBP1,MTMR14,TPM3,EIF4ENIF1,BCL2L13,XRCC4,ZNF24,MKRN3,SH3GLB2,TFIP11,PRTFDC1,PAK5" Pubmed 28330616 Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Pubmed 8.92E-07 2.05E-01 3.10E-04 4.01E-03 92 572 "ACLY,INTS2,AMH,PPFIA2,PPFIA1,PPFIA3,CCAR2,ATP2A2,ATP2B1,CANX,AIFM1,COPB2,CDC42BPB,ANKRD44,CS,GALNT9,PHACTR3,PPP1R16B,PPP6R2,FGFR1OP2,INTS1,DBN1,DBT,SEC16A,DTNB,DNAJB6,CNNM1,KCTD3,ECSIT,TUBB4A,RACK1,FECH,NOP56,TUBA1C,PTPN5,GYG1,RASSF8,MAN1B1,HMGB1,HSPA1L,HSP90AA1,TUBB2B,KCNK3,STMN1,MYO6,MYO9A,OPA1,PCMT1,STRN3,PPP2R2B,PPP2R2C,PPP2R5C,PPP2R5E,PPP5C,MAPK3,CNNM2,PSMD13,CNTLN,PTPRE,PTPRH,PTPRO,DUSP15,SEC61A2,RPL38,RASA3,PPP1R9A,SHMT2,PPP4R3A,INTS9,CAND2,KIF1B,ATP10B,ERBIN,GANAB,ANKRD28,MTCL1,FBXW11,SYNE1,TNS2,ICAM5,PARD3,TP53BP2,TPM4,TRPM2,TUBB2A,CADM1,UCHL1,XPO1,INTS3,RTN4,VANGL2,LAS1L" Pubmed 11331379 Complex trait analysis of the hippocampus: mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "FGFR3,GABRA2,GABRB1,GABRG1,KCNJ9,RXRG" Pubmed 21734292 Neto1 is an auxiliary subunit of native synaptic kainate receptors. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "GRIK1,GRIK2,GRIK4,GRIN1,NETO2,NETO1" Pubmed 16690755 Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "CALB1,GFAP,L1CAM,ROBO1,ROBO2,ROBO3" Pubmed 19366869 The role of Robo3 in the development of cortical interneurons. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "CALB1,GAD1,RELN,ROBO1,ROBO2,ROBO3" Pubmed 15381686 BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ANK3,CNTNAP1,SPTBN4,CNTNAP2,KCNA1,KCNA2" Pubmed 27609886 Identification of an elaborate complex mediating postsynaptic inhibition. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ARHGAP32,GPHN,INSYN1,INSYN2,IQSEC3,ARHGEF9" Pubmed 21104742 IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "SYT6,ETV1,MDGA1,RORB,UNC5D,CUX2" Pubmed 9195986 Identification and characterization of a nerve terminal-enriched amphiphysin isoform. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "AP2A2,AMPH,BIN1,SYNJ1,CLTC,DNM1" Pubmed 18054781 "The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons." Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "CALB1,SLIT2,ROBO1,ROBO2,ARX,SLIT1" Pubmed 28924206 Ephrin-A2 regulates excitatory neuron differentiation and interneuron migration in the developing neocortex. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "CALB1,EFNA2,OLIG2,GAD1,GAD2,ALDH1L1" Pubmed 11746780 Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "MAG,MBP,MOG,OMG,PLP1,UGT8" Pubmed 15345243 Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ALCAM,ATP1A1,SV2A,DLG4,SYP,TMEM163" Pubmed 22606296 Overstimulation of NMDA receptors impairs early brain development in vivo. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "GAD1,GRIN1,L1CAM,MAP2,SLC1A2,SLC1A3" Pubmed 20188654 A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ANK3,CNTNAP1,SPTBN4,NRCAM,GLDN,NFASC" Pubmed 15456859 Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "POU3F2,POU3F4,SOX1,SOX2,SOX3,SOX11" Pubmed 20610380 Ankyrin-B regulates Kir6.2 membrane expression and function in heart. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ANK2,ABCC9,KCNJ11,NTRK2,SLC8A1,ABCC8" Pubmed 19022416 Proteomics analysis of immuno-precipitated synaptic protein complexes. Pubmed 9.18E-07 2.11E-01 3.11E-04 4.02E-03 6 6 "ARHGEF7,GDA,DLG4,GRIA1,GRIA2,GIT1" Pubmed 19948886 Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CALB2,TUBB3,SEMA4D,GAD1,GFAP,MAP2,PLXNB1,RELN,CNTN2" Pubmed 15240797 Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CALB1,FABP7,FGFR1,FGFR3,FOXG1,GFAP,GRIA1,GRIK4,SLC1A3" Pubmed 20029409 Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "LRRC4C,SLIT2,EFNB3,NTNG2,NCAM1,NCAM2,ROBO1,ROBO2,NTNG1" Pubmed 21435555 Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "SLIT2,DLX1,EBF1,L1CAM,MEIS2,ROBO1,ROBO2,SLIT1,CNTN2" Pubmed 19020026 Specific glial populations regulate hippocampal morphogenesis. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CALB1,CALB2,LHX2,TBR1,GFAP,GRIK2,PROX1,RELN,SLC1A3" Pubmed 19605412 Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "ACHE,TBR1,GAD1,MAP2,NOS1,NPY,ARX,SST,SATB2" Pubmed 26880306 Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CAMK2A,PICK1,DLG4,DNM1,GRIA1,GRIA2,GRIN1,SYP,TF" Pubmed 22103416 Differential gene expression in migratory streams of cortical interneurons. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CDH8,CNR1,NRN1,GAD1,RASGEF1B,RELN,PTPRO,PLCB1,FLRT2" Pubmed 9179496 Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "ASTN1,HDAC4,ELMO1,C2CD2L,PTPRT,FCHO1,CUX2,CLIP2,TRIM9" Pubmed 19961580 Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "CALB2,SLIT2,DCC,TBR1,GAP43,GFAP,NFIA,SLC1A3,SATB2" Pubmed 22951639 Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Pubmed 9.40E-07 2.16E-01 3.12E-04 4.03E-03 9 14 "ETV1,FABP7,TBR1,GFAP,HES5,POU3F2,RORB,S100B,GDPD5" Pubmed 23275563 Development and application of a DNA microarray-based yeast two-hybrid system. Pubmed 9.54E-07 2.19E-01 3.12E-04 4.03E-03 33 139 "ADD3,SEMA4G,CAMK2B,PLEKHB1,QKI,CREM,CRY2,TOMM20,SV2A,HEYL,OPTN,UBE2E3,EVL,RAPGEF1,MBD1,NCAM1,NME4,OPCML,PIK3R1,ZNF655,KCTD15,CDIP1,BAALC,ATXN1,UHRF1BP1L,RBM26,TACC1,MLST8,HEY2,RBFOX2,TSC1,SF1,UPF3A" Pubmed 23637331 The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "ASCL1,OLIG2,FOXG1,MBP,PAX6,PDGFRA,PLP1,SOX10" Pubmed 17360631 Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "KIF1A,KIF3A,KIF5A,MAP2,TTLL7,SYP,SYT1,TUBA1A" Pubmed 9742148 Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,CALB2,CCK,GAD1,GAD2,NPY,RELN,SST" Pubmed 17804638 Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,FABP7,TUBB3,GFAP,KIF3A,CNTN2,ZIC1,IFT88" Pubmed 16600913 Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CDK5R1,CDK5R2,CALB2,TUBB3,TBR1,GFAP,HSF2,RELN" Pubmed 26156989 Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB2,SV2A,FABP7,GFRA1,NOS1,RET,SOX10,UCHL1" Pubmed 29666241 Muscularis macrophage development in the absence of an enteric nervous system. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CSF1,CX3CR1,ELAVL3,ELAVL4,TUBB3,KIT,PDGFRA,RET" Pubmed 25150496 The G protein ? subunit G?s is a tumor suppressor in Sonic hedgehog-driven medulloblastoma. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "OLIG1,OLIG2,GLI2,GNAS,MYCN,PTCH1,HHIP,ZIC1" Pubmed 19924828 Expression of PTPRO in the interneurons of adult mouse olfactory bulb. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,CALB2,SYNPR,NCALD,GAD1,MAP2,PTPRO,UCHL1" Pubmed 21485009 Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "BMP7,LDB2,SLIT2,TUBB3,TBR1,GFAP,L1CAM,SOX5" Pubmed 20950430 RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,TUBB3,GFAP,RBPJ,HES5,PAX6,PTCH1,SOX2" Pubmed 21451043 Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "OLIG2,FGFR1,FGFR3,FOXG1,PDGFRA,MAPK3,PTCH1,SOX10" Pubmed 19906969 Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "NRP2,SLIT2,TUBB3,GNAO1,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 18562598 Molecular mechanisms controlling midline crossing by precerebellar neurons. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,SLIT2,ETV1,PAX6,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 25007825 The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "NRP2,CALB1,SYNPR,CHL1,L1CAM,NCAM1,SYP,MICAL1" Pubmed 15273690 Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "NUMB,NUMBL,TUBB3,HES5,MSI1,PAX6,POU3F2,RELN" Pubmed 22573669 Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CALB1,DCLK1,APC2,TUBB3,TBR1,GFAP,NTRK2,RELN" Pubmed 10325223 Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "BMP7,CALB2,LHX2,EMX2,GAD1,GFAP,GRIA1,MAP2" Pubmed 11894096 The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "CNR1,DNM1,SH3GLB1,GAB1,SH3KBP1,SH3GL2,SH3GL3,SH3GLB2" Pubmed 22461560 WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Pubmed 9.65E-07 2.22E-01 3.12E-04 4.03E-03 8 11 "APC,CALB1,FABP7,GFAP,PAX6,S100B,SOX1,SOX2" Pubmed 19923290 The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis. Pubmed 9.66E-07 2.22E-01 3.12E-04 4.03E-03 11 21 "NUMB,CDH2,ETV1,TUBB3,FGFR1,TBR1,HES5,PAX6,MAPK3,CUX2,PARD3" Pubmed 23637172 Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis. Pubmed 9.66E-07 2.22E-01 3.12E-04 4.03E-03 11 21 "FABP7,TUBB3,TBR1,GAD1,GAD2,GFAP,MAP2,SOX2,SOX5,SATB2,RICTOR" Pubmed 22998872 MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Pubmed 9.66E-07 2.22E-01 3.12E-04 4.03E-03 11 21 "OLIG2,FABP7,GFAP,L1CAM,MBP,PAX6,PDGFRA,MAPK3,SLC1A3,SOX2,ACSBG1" Pubmed 18077674 The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. Pubmed 9.77E-07 2.24E-01 3.14E-04 4.06E-03 13 29 "NR0B1,LARGE1,CNR1,GDA,GABRA5,KCNQ3,NKX2-2,NPY,NPTX2,PPP3CA,FBXW7,SATB2,SLC17A7" Pubmed 28942923 Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Pubmed 9.77E-07 2.24E-01 3.14E-04 4.06E-03 13 29 "CALB2,CCK,NDST3,CHST15,TOX3,HS6ST3,NFIX,NOS1,PDE1A,POU3F2,SOX15,SST,HEY1" Pubmed 10737800 Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Pubmed 9.84E-07 2.26E-01 3.16E-04 4.09E-03 84 510 "FMNL2,TMCC3,GRAMD1B,AP1B1,MTUS1,TAOK1,CDC42BPA,PPFIA1,PDE8B,EIF4G3,KIF1A,CARMIL3,AZGP1,BCL2L2,MTMR2,CACNA1A,KALRN,CAMK2A,ISPD,ARHGEF2,CHRM4,MYL6B,FBXO7,SUMF2,PDE4DIP,ARHGAP32,DBI,ATN1,ABCC5,HIPK3,SUGP2,LPAR6,TENM1,GMPR2,FLT1,AFF2,NOP56,PDLIM5,ABLIM2,ZNF44,HIGD1B,TNRC6A,PSRC1,GRIK3,KAT7,USP51,AGFG1,KLHL23,STK32C,VWA2,NOVA1,ENPP2,A2ML1,PRRX1,SYTL2,SIDT1,DUSP15,RIC8B,NEK11,ATP8B4,RYR1,FAM102A,R3HDM2,EPC1,RCOR3,IGSF9B,UNC80,KDM4B,ZSWIM8,ARHGAP26,VPS13A,SZT2,PCDHGA11,PCDHA1,TJP1,ASXL3,TNS1,ELP5,ZIC1,ZNF225,PRDM2,NAV2,LINC00632,SLC39A12" Pubmed 28794184 Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Pubmed 1.03E-06 2.37E-01 3.31E-04 4.27E-03 12 25 "NRXN1,PUM1,ATN1,GFAP,GIT1,SNAP25,SOX2,SYT1,PUM2,DICER1,CBX5,PARP6" Pubmed 27178982 Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition. Pubmed 1.03E-06 2.37E-01 3.31E-04 4.27E-03 12 25 "CDK5R1,PARD6A,DLG2,OLIG2,FLT1,CHL1,MEIS2,PRKCZ,PTCH1,CNTN2,ZEB1,PARD3" Pubmed 17507568 Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. Pubmed 1.03E-06 2.37E-01 3.31E-04 4.27E-03 12 25 "ASCL1,DLX1,ETV1,TUBB3,TBR1,GAD1,HES5,RELN,SLIT1,ZIC1,ZIC2,ZIC3" Pubmed 19911011 Mutation of ARHGAP9 in patients with coronary spastic angina. Pubmed 1.06E-06 2.43E-01 3.38E-04 4.36E-03 15 38 "ARHGEF1,ARHGEF2,CHN2,NGEF,ARHGEF6,DLC1,OPHN1,ARHGEF10L,ARHGEF9,MCF2L,ARHGEF12,ARHGAP9,TIAM1,TRIO,VAV2" Pubmed 15383276 "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease." Pubmed 1.14E-06 2.61E-01 3.63E-04 4.69E-03 22 74 "CEP126,GPRASP2,APLP1,BARD1,HAP1,CLTC,CRMP1,FEZ1,ARMCX2,PLEKHM1,DNM1L,NSG2,GDF9,TCERG1,KAT7,FICD,ZHX1,GIT1,PTN,SH3GL3,TAL1,DNALI1" Pubmed 21532573 Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Pubmed 1.23E-06 2.84E-01 3.93E-04 5.08E-03 18 53 "ARID1A,CCAR2,NCOR1,NCOR2,MYEF2,OLIG1,SALL3,DOCK7,RFX3,SOX8,SALL1,SMARCA4,SMARCC2,SMARCE1,SOX2,SOX5,ZEB1,ZNF24" Pubmed 29576527 "Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability." Pubmed 1.25E-06 2.87E-01 3.97E-04 5.13E-03 34 147 "USP31,USP35,USP28,USP37,BLM,USP6,USP2,TJP2,SMARCAL1,USP3,DTNB,VPS26C,USP16,USP19,DHRS4,USP54,NF1,MINDY2,USP47,KIF7,USP33,FNBP1,ZSWIM8,MLST8,AGTPBP1,DMXL2,RPGRIP1L,USP22,SZT2,FRYL,TJP1,UBC,UCHL1,RICTOR" Pubmed 18848646 Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Pubmed 1.32E-06 3.03E-01 4.19E-04 5.41E-03 14 34 "LRFN2,LRFN1,LRRC4C,LRIG1,ADGRA3,LINGO1,LRRC4B,LRIT2,NTRK2,NTRK3,LRRN3,LRFN5,LRRC4,LRRC24" Pubmed 22008794 Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Pubmed 1.34E-06 3.09E-01 4.26E-04 5.51E-03 33 141 "KLHL32,ADCY8,ALCAM,DDO,MARCH3,MYOM2,CDO1,CLU,LRIG1,ERC2,TOX,F5,SCARA3,CHL1,GNG4,GPER1,GRIK3,GSN,WIF1,SYNPO,IGSF1,KCNA2,JAKMIP1,SMOX,TMEM255A,TMEM100,CPEB3,CLSTN2,EPB41L3,PCDHB15,TF,CFAP52,NAV3" Pubmed 16335952 "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." Pubmed 1.37E-06 3.15E-01 4.34E-04 5.61E-03 50 257 "SERPINA3,AGT,ADGRF5,SPARCL1,ALCAM,APP,AZGP1,BCHE,C5,NIPA1,CACNA2D1,JAM2,CLU,CNTN1,CP,CSF1R,SIRPA,SIRPB1,F5,F8,OLFM1,FGFR1,PCYOX1,GAA,CHL1,LYVE1,CNDP1,LPAR4,ADAMTS13,HP,IL6ST,ITIH2,KIT,L1CAM,LAMA2,LAMP2,CPNE9,MDGA1,NCAM1,NRCAM,NTRK2,CNTN3,PLTP,PLXNB1,PTPRG,PTPRZ1,SELL,APOM,CNTN2,TF" Pubmed 28584103 Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex. Pubmed 1.50E-06 3.45E-01 4.72E-04 6.11E-03 10 18 "ASCL1,TUBB3,FOXG1,TBR1,L1CAM,PAX6,FEZF2,SOX2,CNTN2,SATB2" Pubmed 24082127 The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Pubmed 1.50E-06 3.45E-01 4.72E-04 6.11E-03 10 18 "ASCL1,CALB1,EBF1,PPP1R1B,FOXG1,MEIS2,NPY,PENK,SYN1,TAC1" Pubmed 21508241 Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain. Pubmed 1.50E-06 3.45E-01 4.72E-04 6.11E-03 10 18 "NRP2,CALB1,SLIT2,PPP1R1B,FLT1,GAD1,ROBO1,ROBO2,SLIT1,SST" Pubmed 19455133 Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Pubmed 1.50E-06 3.45E-01 4.72E-04 6.11E-03 10 18 "CAMK2A,GDA,DLG2,DLG3,DLG4,BAIAP2,GRIN1,KCNA4,ARC,NETO1" Pubmed 8653788 Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Pubmed 1.50E-06 3.45E-01 4.72E-04 6.11E-03 10 18 "ACHE,SV2B,SV2A,DNM1,SYT3,SYT17,NEFH,SYP,SYT1,SYT4" Pubmed 26671461 Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Pubmed 1.56E-06 3.59E-01 4.91E-04 6.34E-03 15 39 "AXIN2,CALB2,LHX2,DLX1,EMX2,ETV1,TBR1,SMAD1,PAX6,PBX1,RELN,RORB,PDZRN3,SMOC1,CUX2" Pubmed 20181579 The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. Pubmed 1.57E-06 3.61E-01 4.91E-04 6.34E-03 13 30 "CALB1,CALB2,DLX1,OLIG2,ETV1,TUBB3,PPP1R1B,GAD1,NKX6-2,GNAL,NPY,SST,ZIC1" Pubmed 27321927 Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity. Pubmed 1.57E-06 3.61E-01 4.91E-04 6.34E-03 13 30 "GAS7,CASK,CACNA1E,TBR1,ZMYND11,NFYA,FEZF2,ITSN1,SMARCD3,MYCBP2,GSE1,SATB2,ZFPM2" Pubmed 26830346 Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation. Pubmed 1.57E-06 3.61E-01 4.91E-04 6.34E-03 13 30 "BMP7,LDB2,LHX2,EPHA5,EPHB1,TUBB3,TBR1,L1CAM,PRKCG,FEZF2,SLC6A7,SATB2,SEMA3B" Pubmed 23942779 A genome-wide association study of behavioral disinhibition. Pubmed 1.57E-06 3.61E-01 4.91E-04 6.34E-03 13 30 "SYT6,NRXN1,SEPT9,FAXC,HSP90AA1,OPCML,ZNF827,SLC6A15,GALNT10,TMEM132D,CSMD1,NEIL2,LRTM2" Pubmed 22235033 Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus. Pubmed 1.70E-06 3.90E-01 5.30E-04 6.84E-03 16 44 "CACHD1,CADPS,NRP2,ELAVL2,FGFR3,IGFBPL1,KCND2,RSPO2,NFIA,NFIX,NTRK3,PROX1,RFX4,TNFRSF19,CUX2,ZIC2" Pubmed 14574404 The DNA sequence and analysis of human chromosome 6. Pubmed 1.72E-06 3.95E-01 5.37E-04 6.93E-03 97 621 "ABCF1,LRFN2,HACE1,KIF6,FGD2,C6orf89,DDO,CPNE5,ATP6V1G2,RIPK1,DST,SYNJ2,DDR1,MAP7,PPT2,QKI,LY86,FHL5,CNR1,AKAP7,COL9A1,COL11A2,TBPL1,NRSN1,ZSCAN23,KIAA0408,ZBTB24,KIAA0319,SNAP91,EDN1,RGS17,NRN1,FABP7,SYNCRIP,FOXO3,FUT9,FYN,GABBR1,TRAF3IP2,HBS1L,BRPF3,FAXC,TTBK1,GRM1,BTN2A1,BACH2,ELOVL5,HSF2,HSPA1L,SMAP1,TJAP1,TUBB2B,STXBP5,NCOA7,PACRG,MDFI,AFDN,MOG,MYO6,NFYA,PDCD2,POU3F2,UHRF1BP1,ZDHHC14,REV3L,MRPS18A,MRAP2,RPS6KA2,ATXN1,SCAF8,SGK1,ANKRD6,ZKSCAN3,KIF13A,LMBRD1,TRERF1,CDK19,TAB2,NKAIN2,ELOVL4,APOM,POPDC3,SYNE1,NR2E1,HEY2,DAAM2,PPIL6,DCBLD1,TUBB2A,RPL7L1,MTCH1,MICAL1,NELFE,PDSS2,GOPC,SMIM8,RNF146" Pubmed 20080794 "Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1." Pubmed 1.75E-06 4.02E-01 5.40E-04 6.98E-03 12 26 "LHX2,GAD1,MAPT,NOS1,NPY,PENK,SST,SSTR2,TAC1,TRH,SLC17A7,SLC17A6" Pubmed 18448089 Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Pubmed 1.75E-06 4.02E-01 5.40E-04 6.98E-03 12 26 "AXIN2,CALB1,CALB2,ETV1,FOXG1,TBR1,GAD1,MAP2,RELN,RORB,SOX5,CUX2" Pubmed 18957218 Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Pubmed 1.75E-06 4.02E-01 5.40E-04 6.98E-03 12 26 "CDH8,CRYM,EMX2,ETV1,TUBB3,TBR1,GAD1,PAX6,POU3F2,PRKCG,RORB,CUX2" Pubmed 21976438 Primary cilia and Gli3 activity regulate cerebral cortical size. Pubmed 1.75E-06 4.02E-01 5.40E-04 6.98E-03 12 26 "ASCL1,CALB2,TJP2,EMX2,TUBB3,TBR1,KIF3A,KITLG,PAX6,PTCH1,CUX2,IFT88" Pubmed 22992956 Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "ZNF521,ZEB2,GBX2,PAX6,POU3F2,POU3F4,SOX1,SOX2,SOX3,ZIC2,ZIC3" Pubmed 28386764 Roles of tau protein in health and disease. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "TAOK1,MARK4,DYRK1A,FYN,TTBK1,MAPT,MARK1,MARK3,PPP5C,TTBK2,SIRT1" Pubmed 20237275 Dicer is required for the transition from early to late progenitor state in the developing mouse retina. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "CALB1,CALB2,ELAVL3,ELAVL4,TUBB3,PAX6,PROX1,RLBP1,SLC1A3,SOX2,DICER1" Pubmed 24360543 Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "LHX2,EFNB3,ELAVL3,ELAVL4,EPHA5,EPHB1,ROBO1,ROBO2,SOX2,ROBO3,ZIC2" Pubmed 25294941 ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "DYNLL1,OLIG2,KIF3A,NKX2-2,PAX6,PTCH1,RFX3,IFT122,ATMIN,TP53BP1,IFT88" Pubmed 22817342 Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "SEMA7A,TBR1,CPLX2,LYVE1,INSM1,NEUROD1,PAX6,RELN,RLBP1,WLS,SSTR2" Pubmed 19020049 Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "CCK,FOXG1,TBR1,GBX2,HES5,NEUROD1,NEUROD2,NPY,PROX1,RELN,SST" Pubmed 18391953 Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Pubmed 1.76E-06 4.05E-01 5.40E-04 6.98E-03 11 22 "SLC12A5,SLC12A6,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,SLC12A2,SLC12A4" Pubmed 25737280 "Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt." Pubmed 1.90E-06 4.37E-01 5.83E-04 7.53E-03 51 267 "ARID1A,OGT,ARHGAP5,ATP2A2,ATP2B1,DST,MTMR2,CALM1,CDC42,COPB2,CNOT8,PLAA,CLTC,SLC4A7,MATR3,DPYSL2,DNM1L,EIF4G1,EIF4G2,WAC,TUBB3,TUBB4A,RACK1,IP6K2,FAM49B,ATP6V1H,TXNL4A,GLS,PRRC2B,HMGCR,HSP90AA1,MKLN1,OGDH,OPA1,GPR85,PKN2,OCIAD1,MCMBP,SAFB,SFPQ,TRA2B,FBXO11,LIMCH1,TROVE2,CBX5,TMPO,RBFOX2,XPO1,SLC38A1,CSDE1,RTN4" Pubmed 29078390 "WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy." Pubmed 2.00E-06 4.60E-01 6.12E-04 7.91E-03 14 35 "STMN2,L1CAM,MAPT,NEFH,PAX6,PPP2R2B,ATG16L1,WDR37,WDR47,WDTC1,KIF21B,DMXL2,ZNF106,HIRA" Pubmed 26740489 Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CNTNAP1,FABP7,TUBB3,TBR1,GFAP,HES5,PAX6,S100B,SOX2" Pubmed 17640523 An essential switch in subunit composition of a chromatin remodeling complex during neural development. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "DPF1,ARID1A,ACTL6B,PBRM1,SMARCA4,SMARCC2,SMARCD3,SMARCE1,DPF3" Pubmed 23821580 Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "NRP2,SLIT2,ENO2,NCAM1,NCAM2,ROBO1,ROBO2,S100B,SLIT1" Pubmed 20507551 Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB1,CCK,TBR1,GAD1,GAD2,MAPT,NOS1,NPY,SST" Pubmed 18215621 SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB2,CRYM,TBR1,RELN,FEZF2,RORB,S100B,SOX5,CUX2" Pubmed 12368262 "Identification of a polymorphic, neuron-specific chromatin remodeling complex." Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "ARID1A,SRGAP3,TUBB3,ACTL6B,GFAP,PBRM1,SMARCA4,SMARCC2,SMARCE1" Pubmed 16157277 Fezl is required for the birth and specification of corticospinal motor neurons. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "LDB2,CRYM,ZEB2,PPP1R1B,TBR1,POU3F2,FEZF2,RORB,CUX2" Pubmed 24451661 miRNAs are Essential for the Survival and Maturation of Cortical Interneurons. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "EBF1,TBR1,GAD1,GAD2,IGF1,NPY,SOX6,SST,DICER1" Pubmed 23454273 Role for Lhx2 in corticogenesis through regulation of progenitor differentiation. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "LHX2,ETV1,TUBB3,TBR1,HES5,PAX6,RORB,CUX2,HEY1" Pubmed 23785148 Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "DPF1,ARID1A,ACTL6B,PBRM1,SMARCA4,SMARCC2,SMARCD3,SS18,DPF3" Pubmed 24496615 "Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice." Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB1,CALB2,CAMK2A,EGFR,OLIG2,FGFR1,GFAP,NEUROD1,PROX1" Pubmed 25079316 Glial origin of mesenchymal stem cells in a tooth model system. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "FABP7,TUBB3,GFAP,MBP,MITF,PLP1,S100B,SOX10,UCHL1" Pubmed 21989918 "Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis." Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB1,CALB2,ELAVL3,ELAVL4,FABP7,NOS1,NPY,SOX2,TAC1" Pubmed 27667971 Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "NRP2,TUBB3,FOXG1,NCAM1,NEUROD1,RELN,ROBO2,SLIT1,SOX2" Pubmed 19332887 Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "ASCL1,FABP7,TUBB3,GFAP,NUMA1,GPSM2,RELN,SLC1A3,VANGL2" Pubmed 20619750 ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB1,ETV1,TUBB3,NEFH,PAX6,RLBP1,TJP1,PARD3,TP53BP2" Pubmed 20713522 Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CALB1,CALB2,ERBB4,FOXG1,GAD1,L1CAM,NPY,RELN,SST" Pubmed 29659809 A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Pubmed 2.15E-06 4.93E-01 6.41E-04 8.29E-03 9 15 "CACNA1A,CALB1,CALB2,DRD1,TBR1,PAX6,ARX,SST,TAC1" Pubmed 23400010 Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Pubmed 2.17E-06 4.98E-01 6.47E-04 8.37E-03 21 71 "ADARB2,TNRC6C,ARRB1,JAZF1,COX4I1,SLC35F1,SEC31B,GRIN3A,IQGAP2,PPARGC1A,IGF1,MEF2C,NELL1,WDR37,PHLDB1,LINC00511,FMN2,CA10,STOX2,PCDH15,ZDHHC20" Pubmed 22190034 Global landscape of HIV-human protein complexes. Pubmed 2.18E-06 5.01E-01 6.50E-04 8.40E-03 76 457 "OSBPL6,CNTNAP1,APP,ARRB2,CCAR2,ATP2A2,ATP2B1,DPY19L3,AP1M1,BTRC,CANX,CCNT1,TBRG4,CLGN,CHI3L2,PLAA,SUMF2,MAGED1,COX4I1,ACBD5,NCOR1,OSBPL3,DCAF8,MATR3,CEP170,G3BP2,ACOT8,COPS4,RTN3,PTK2B,EFEMP1,FECH,ATP5PD,EVL,ERGIC3,AHCYL1,MTHFD2,NFU1,COPS8,OS9,PSIP1,IDH3A,AFF1,MRPL42,CTNNA3,OLA1,PKM,PSAT1,PPP2R5E,ANKHD1,RNASE1,RNH1,SARS,FNIP1,CASC3,AMBRA1,IFT122,SNRPN,KIF21B,EMC1,CAND2,TAB2,GANAB,FBXW11,SMG6,ARHGEF12,PUM2,AHCYL2,SIRT1,ZFP91,TRPS1,MTCH1,TBC1D15,XPO1,CSDE1,RTN4" Pubmed 24198358 A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. Pubmed 2.28E-06 5.23E-01 6.77E-04 8.75E-03 15 40 "FGF17,TUBB3,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,IGF1,NEFH,NTRK2,NTRK3,RET,SOX10" Pubmed 12679517 The G protein-coupled receptor repertoires of human and mouse. Pubmed 2.38E-06 5.47E-01 6.88E-04 8.89E-03 22 77 "ADGRF5,ADGRB2,ADGRB3,GPR146,GPR37L1,DRD1,GPR153,ADGRA1,GPR17,GPR22,LPAR4,GPR26,GRM2,GRM5,GRM7,GPR62,GPR155,GPR137C,GPR173,LGR4,ADGRL3,GPR161" Pubmed 23754746 Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Pubmed 2.39E-06 5.48E-01 6.88E-04 8.89E-03 17 50 "C1QTNF3,RAB33A,CSF2RA,ST18,ZDHHC15,OCRL,MAGEL2,SH3KBP1,SLC6A8,SNRPN,PCDHB15,PCDHB4,PCDHB3,PCDHA6,PCDHA1,MKRN3,TMEM163" Pubmed 17192421 Involvement of the myelin-associated inhibitor Nogo-A in early cortical development and neuronal maturation. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CALB1,TUBB3,GAD1,GAD2,MAP2,CNTN2,RTN4" Pubmed 19103752 Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "BTRC,TUBA1B,GLI2,TUBA1C,SMAD1,SMAD9,TUBA1A" Pubmed 10707971 Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "NRP2,CALB1,CALB2,MBP,PROX1,CNTN2,SLC30A3" Pubmed 19631204 HeyL regulates the number of TrkC neurons in dorsal root ganglia. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "HEYL,ETV1,NTRK2,NTRK3,SOX10,HEY1,HEY2" Pubmed 20170731 Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "INA,FABP7,TUBB3,TBR1,NEFH,RELN,CNTN2" Pubmed 26671463 TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "ANK3,SPTBN4,CALB1,PRC1,MAPT,TRIM46,NFASC" Pubmed 18832395 Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "PTCH2,BOC,GFAP,GLI2,PTCH1,HHIP,ZIC2" Pubmed 7553862 Complexins: cytosolic proteins that regulate SNAP receptor function. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CPLX2,CPLX1,SNAP25,STX1A,STXBP1,SYP,SYT1" Pubmed 24069373 Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "PICK1,DLG2,DLG4,GRIK1,GRIN1,NTRK2,SORCS3" Pubmed 12057195 Accessory protein recruitment motifs in clathrin-mediated endocytosis. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "AP2A1,AP2A2,AMPH,SYNJ1,CLTA,CLTC,EPN1" Pubmed 2561974 Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CYBB,DMD,F8,GABRA1,GABRA2,GABRA3,GABRB1" Pubmed 18719084 Sox2 plays a role in the induction of amacrine and Müller glial cells in mouse retinal progenitor cells. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CALB1,CALB2,ELAVL3,ELAVL4,GLUL,PAX6,SOX2" Pubmed 12659632 "Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3." Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "EFNA2,ZMYND11,ZHX1,NFYA,ATXN1,ATF7IP,ZHX3" Pubmed 16407979 Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "APBB1,APBB2,APP,TUBB3,L1CAM,RELN,CNTN2" Pubmed 19150975 Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "APC,TBR1,GFAP,MBP,PAX6,TSC1,TSC2" Pubmed 16148239 Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "APC,ASCL1,OLIG1,OLIG2,MBP,NKX2-2,SOX10" Pubmed 16551741 Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CNTNAP1,CALB1,GFAP,KCNA1,SPTAN1,EPB41L3,UGT8" Pubmed 10841580 Mouse numb is an essential gene involved in cortical neurogenesis. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "NUMB,FGF17,EMX2,FOXG1,MAP2,PAX6,TMEM163" Pubmed 21144999 Superresolution imaging of chemical synapses in the brain. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "BSN,DLG4,SHANK1,GABBR1,PCLO,GRIA1,RIMS1" Pubmed 15634788 "Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex." Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "ELAVL2,ELAVL3,ELAVL4,TUBB3,TBR1,PAX6,RELN" Pubmed 24449836 Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "OLIG1,OLIG2,MBP,NKX2-2,PDGFRA,PLP1,SOX10" Pubmed 19544586 In vitro and in vivo differentiation of human embryonic stem cells into retina-like organs and comparison with that from mouse pluripotent epiblast stem cells. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "ELAVL3,ELAVL4,TUBB3,GFAP,PAX6,RPE65,SYP" Pubmed 23665444 Expression of the murine transcription factor SOX3 during embryonic and adult neurogenesis. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "CALB1,FABP7,TUBB3,GFAP,PAX6,SOX2,SOX3" Pubmed 17018287 Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Pubmed 2.39E-06 5.49E-01 6.88E-04 8.89E-03 7 9 "DLG4,EPS8,GRIA1,GRIN1,GRIN2C,SYN1,SYP" Pubmed 25131634 Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice. Pubmed 2.53E-06 5.82E-01 7.28E-04 9.41E-03 23 83 "ACHE,APP,BCHE,CAMK2A,CHRNA4,CSF1,VCAN,ELAVL3,FCGR1A,GABRA2,GABRA4,GABRB3,GABRG1,MAPT,MBP,MSR1,NTRK2,NTRK3,PPP3CC,MAPK8,KCNIP3,MAPK12,SST" Pubmed 28965759 Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "TUBB3,TBR1,GFAP,NEUROD1,PAX6,S100B,SATB2,METTL3" Pubmed 23342162 Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "MTMR2,GAA,PCSK1N,HAS2,PAX6,FAT4,SNCA,KIF1B" Pubmed 26030886 "The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1." Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CALB1,CALB2,GFAP,NCAM1,NEUROD1,PAX6,SLC17A7,SLC17A6" Pubmed 21125652 Peripheral contributions to olfactory bulb cell populations (migrations towards the olfactory bulb). Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CALB1,CALB2,FABP7,TUBB3,GAP43,MAP2,S100B,SOX2" Pubmed 20871603 SOX9 induces and maintains neural stem cells. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "PROM1,TUBB3,GFAP,NCAM1,SOX8,SLC1A3,SOX2,SOX10" Pubmed 11937501 Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ADGRB1,DLG3,DLG4,GRIN1,GRIN2C,GRIN2D,KCNA1,KCNA4" Pubmed 16225856 The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CALB1,CALB2,GAD1,L1CAM,NCAM1,PAX6,ROBO3,CNTN2" Pubmed 17803915 SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CASK,RPH3A,RIMS1,SNAP25,STXBP1,SYN2,SYP,UBC" Pubmed 10734137 "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms." Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "KLHL3,SYNCRIP,SYT3,SYT9,SYT11,SYT1,SYT4,SYT5" Pubmed 12571102 FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CDH8,EMX2,FGFR1,FGFR3,FOXG1,TBR1,GAD1,PAX6" Pubmed 25218043 "Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice." Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CNIH2,SYNGR3,DLG4,OLFM1,GRIA1,GRIA2,GRIA4,SYP" Pubmed 21545793 Netrin1 is required for neural and glial precursor migrations into the olfactory bulb. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CALB1,CALB2,OLIG2,TUBB3,GFAP,NCAM1,PDGFRA,S100B" Pubmed 15331610 The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2A,TUBB1,TUBA1A" Pubmed 20531390 Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CALB1,CANX,GFAP,ATXN1,SLC1A2,SLC1A3,CDK5RAP3,SOX2" Pubmed 16301330 Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "APBB1,APP,KIF1A,KIF5A,KIF5C,KLC1,KIF1B,KLC2" Pubmed 17329426 Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "SEMA6A,SLIT2,LHX2,GAD1,NPTX1,NPTX2,NTNG1,SLIT1" Pubmed 20151419 Differential gene expression in migrating cortical interneurons during mouse forebrain development. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ASTN1,CALB1,DGKG,CHL1,GAD1,PTPRT,MGAT5B,WNT7A" Pubmed 18840685 "SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons." Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ETV1,TBR1,MAP2,RELN,FEZF2,RORB,SOX5,ZFPM2" Pubmed 11700294 Identification of epilepsy genes in human and mouse. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CACNA1A,CACNB4,CACNA2D2,ADGRV1,CACNG2,MYO5A,PLP1,PMP22" Pubmed 28041852 The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CCK,SLC32A1,GAD1,GAD2,NTRK3,PRKCG,RET,RORB" Pubmed 18816825 Baf60c is a component of the neural progenitor-specific BAF complex in developing retina. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ELAVL3,ELAVL4,TUBB3,HES5,SLC1A3,SMARCA4,SMARCD3,SOX2" Pubmed 25988834 Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CDH2,OLIG2,TUBB3,TBR1,GFAP,MBP,AFDN,SOX2" Pubmed 16540508 Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "SLIT2,DLX1,GAD1,GAP43,NCAM1,RELN,ARX,SLIT1" Pubmed 26209882 In vivo overactivation of the Notch signaling pathway in the developing cochlear epithelium. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "EMX2,TUBB3,HES5,MYO6,PROX1,SOX2,HEY1,HEY2" Pubmed 28826478 Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "CACNA2D1,ABCC9,MBNL2,MBNL1,PPP3CA,PPP3CB,PPP3CC,CLASP1" Pubmed 8615909 "Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma." Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ACTN2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLG4,GRIN1,GRIN2D" Pubmed 21800304 Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ASTN1,CALB1,CDH2,GFAP,NFIX,PAX6,SLC1A3,CNTN2" Pubmed 18031722 LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "OLIG2,ETV1,GFAP,LIFR,NKX2-2,PDGFRA,S100B,SOX10" Pubmed 24209760 Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "ASCL1,CALB2,OLIG2,GFAP,IL6R,PAX6,SOX2,SATB2" Pubmed 22241839 Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor. Pubmed 2.65E-06 6.08E-01 7.33E-04 9.48E-03 8 12 "GRIA1,GRIK2,GRIK3,GRIN1,GRM1,GRM5,NEFH,SLC17A6" Pubmed 15761153 High-throughput mapping of a dynamic signaling network in mammalian cells. Pubmed 2.82E-06 6.47E-01 7.79E-04 1.01E-02 49 256 "APBB2,BMPR1B,ARHGEF7,ARHGEF1,CDC42,SOCS6,CHN1,CHN2,PLEKHB1,FHL5,ARHGEF6,RNF14,OSBPL3,PPP1R16B,GIT2,RHOBTB1,PARD6A,PLEKHO1,RASL12,ECSIT,UBE2E3,MEX3B,USP21,NEK6,RAB30,CLASRP,SMAP1,IRF8,INPP5B,LIMS1,LMO2,SMAD1,SNTG1,GNG2,CDK14,SH3KBP1,PPP2R2B,PPP3CC,ATG16L1,VEPH1,RGS3,RTKN,PREX2,TTC17,FCHO1,TNNT1,RASD2,UBTF,RNF146" Pubmed 24491816 The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells. Pubmed 2.87E-06 6.60E-01 7.92E-04 1.02E-02 12 27 "CA8,CALB1,GAD1,GOLGB1,NEFH,PAX6,RELN,PTCH1,SLC1A6,VLDLR,LRP8,SLC17A6" Pubmed 18649358 Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. Pubmed 2.87E-06 6.60E-01 7.92E-04 1.02E-02 12 27 "GALNT13,GPR158,PKP4,GRIN3A,EPHB1,MYH3,PACSIN1,KDM4C,PLCB1,MTCL1,SYNE1,PSD3" Pubmed 15147765 Emx1 and Emx2 cooperate in initial phase of archipallium development. Pubmed 2.87E-06 6.60E-01 7.92E-04 1.02E-02 12 27 "NRP2,NOG,LHX2,CNTN1,DLX1,EMX2,EPHB1,FOXG1,KITLG,CNTN3,PAX6,PROX1" Pubmed 24027274 Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "MAPT,NTRK2,NTRK3,PRKCG,MAPK3,RET,SST,TAC1,SLC17A7,SLC17A6" Pubmed 15698476 "HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?" Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "TUBD1,TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Pubmed 20219685 "Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression." Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "AXIN2,ZEB2,EMX2,NR3C1,MAPT,CLASP2,TCF7L2,TSC2,WNT7A,FZD3" Pubmed 26944677 ?linc1 encodes a long noncoding RNA that regulates islet ?-cell formation and function. Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "CHGA,CHGB,DISP2,NEUROD1,NKX2-2,NNAT,PAX6,SCG5,ARX,SST" Pubmed 16651659 SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "CALB2,TUBB3,GFAP,HES5,NEUROD1,PAX6,RLBP1,SOX1,SOX2,TMEM163" Pubmed 15691386 HIV-1 Tat protein enhances microtubule polymerization. Pubmed 2.89E-06 6.65E-01 7.92E-04 1.02E-02 10 19 "TUBD1,TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Pubmed 28700664 "Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program." Pubmed 2.95E-06 6.78E-01 8.07E-04 1.04E-02 35 159 "SYN3,STX16,CAST,CERS5,CHN1,JAM2,CP,CRYM,ARHGEF10,DBN1,KIAA0753,RPS6KL1,HEYL,LPAR6,NCALD,FOXO3,CINP,GHR,DBF4,HSF2,IRF8,RBPJ,IL6ST,NEFH,NRCAM,IGSF11,PCSK5,SH3TC2,ENOX1,KIF1B,TMEM136,TMEM151B,AP4E1,ZNF346,IFT88" Pubmed 18094027 Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Pubmed 2.98E-06 6.85E-01 8.15E-04 1.05E-02 14 36 "LHX2,EBF1,FOXG1,TBR1,GAP43,GBX2,NKX2-2,PAX6,IRX1,PROX1,FEZF2,ARX,SSPO,TCF7L2" Pubmed 17192257 Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Pubmed 3.02E-06 6.93E-01 8.23E-04 1.06E-02 22 78 "CDK10,MARK4,CAMK2D,CAMK2G,MAP4K4,CSNK1E,DYRK1A,EGFR,PTK2B,FER,FYN,MAP4K5,MARK1,MARK3,CDK18,PRKCB,MAPK3,MAPK8,MAPK9,PTK2,RPS6KA2,TNIK" Pubmed 24561123 CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human ??-adrenergic receptor. Pubmed 3.05E-06 7.02E-01 8.32E-04 1.08E-02 18 56 "ADRB2,ARHGAP5,ARHGDIA,RGS20,ARRB2,RGS11,RGS9,CCKBR,CD81,ADGRG1,RGS17,GMPR2,RACK1,GPR37,IL6R,RAB3A,RGS10,WNK1" Pubmed 19036983 A crucial role for primary cilia in cortical morphogenesis. Pubmed 3.08E-06 7.08E-01 8.34E-04 1.08E-02 11 23 "AXIN2,LHX2,EMX2,EPHB1,TUBB3,FOXG1,MAPT,PAX6,RELN,PTCH1,IFT88" Pubmed 22522171 Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Pubmed 3.08E-06 7.08E-01 8.34E-04 1.08E-02 11 23 "OLIG1,OLIG2,TUBB3,MBP,NKX2-2,PDGFRA,RAP1GAP,S100B,SLC1A3,SOX10,UGT8" Pubmed 24463367 Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells. Pubmed 3.08E-06 7.08E-01 8.34E-04 1.08E-02 11 23 "CALB2,LHX2,TUBB3,GFAP,GRIK1,PAX6,PROX1,RLBP1,SLC1A3,SST,TAC1" Pubmed 26371318 Lhx2 regulates the timing of ?-catenin-dependent cortical neurogenesis. Pubmed 3.08E-06 7.08E-01 8.34E-04 1.08E-02 11 23 "AXIN2,LHX2,FABP7,TBR1,GFAP,PAX6,POU3F2,RELN,HES6,SLC1A3,SATB2" Pubmed 22479201 The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. Pubmed 3.08E-06 7.08E-01 8.34E-04 1.08E-02 11 23 "CALB1,CALB2,TBR1,GAD1,GFAP,L1CAM,RELN,PTCH1,RFX3,SLC1A3,SATB2" Pubmed 21875946 "Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/?-catenin signaling." Pubmed 3.21E-06 7.38E-01 8.70E-04 1.12E-02 20 67 "NRP2,WASF1,AIFM1,CDH2,ABI1,CELSR3,CDHR1,NCKAP1,WASF3,ADGRA3,PCDH9,FAT3,MAPK3,CNNM2,NCR3LG1,FAT4,PCDHGA11,UBC,PCDH20,ITM2C" Pubmed 21725061 CIN85 interacting proteins in B cells-specific role for SHIP-1. Pubmed 3.26E-06 7.48E-01 8.80E-04 1.14E-02 17 51 "AP2A1,AP2A2,HIP1R,SEPT7,CLTC,DBT,DNM2,PDCD6IP,SEPT9,IDH3B,PIK3AP1,PIK3CD,PIK3R1,SH3KBP1,SPTAN1,UBTF,WIPF1" Pubmed 26166575 OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum. Pubmed 3.27E-06 7.51E-01 8.82E-04 1.14E-02 15 41 "FGF17,ARHGAP22,SLIT2,DLX1,OLIG1,EN2,OLIG2,ETV1,TUBB3,SALL3,ROBO2,ARX,TLL2,ZIC1,TMEM163" Pubmed 24639526 RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Pubmed 3.95E-06 9.07E-01 1.06E-03 1.38E-02 41 202 "ABAT,KIDINS220,CDC42BPA,ATP1A1,ATP1A2,ATP1A3,EIF4G3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CANX,LRRFIP1,CLTC,CDC42BPB,CREB5,MATR3,DCTN1,DMPK,DSCAM,EEF1A2,EIF4G1,TUBA1B,TUBA8,ZNF638,HNRNPK,DOCK7,USP54,MAP4,AFDN,NUMA1,PIK3C2A,PIGG,PTK2,MYH14,LGR4,SAFB,ARHGEF40,MYCBP2,PRRC2C,UBC" Pubmed 20362541 An Oct4-centered protein interaction network in embryonic stem cells. Pubmed 3.98E-06 9.13E-01 1.07E-03 1.38E-02 35 161 "ARID1A,MTA3,NR0B1,OGT,EP400,ZMYM4,KMT2C,ELMSAN1,MED24,MED12,KAT8,SALL3,BRD8,RBPJ,KIF5A,RCOR2,CHAMP1,ING3,MED1,DPF2,PBRM1,SALL1,KANSL3,SMARCA4,SMARCC2,SMARCE1,SOX2,PEG10,POGZ,TAF6,TAF9,SATB2,CABIN1,EMSY,JMJD1C" Pubmed 20546612 The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. Pubmed 4.01E-06 9.22E-01 1.08E-03 1.39E-02 24 91 "HACE1,LCORL,JAZF1,NOG,EFEMP1,DOT1L,BVES,ZNF678,MRPL42,PENK,BCAS3,PTCH1,PEX2,RBBP8,ZFHX4,RPS20,SH3GL3,SCMH1,COLGALT2,ADAMTS17,POPDC3,HHIP,ZBTB38,ADAMTSL3" Pubmed 19060904 An empirical framework for binary interactome mapping. Pubmed 4.34E-06 9.97E-01 1.17E-03 1.51E-02 45 231 "KIF6,PPFIA1,ARRB2,AP1M1,USP6,CBFA2T2,EVI5L,SLC22A6,RAB33A,HOMER3,APPL1,DCAF8,PITPNC1,ZBTB24,ZC3H11A,EML1,HSD17B14,MAD2L2,SYNCRIP,STAMBP,TUBGCP4,LIMS1,MDFI,DBNL,NFYA,C19orf57,MAPK9,ZSCAN32,RAB3IL1,SETD5,RCOR3,SNAP25,EPB41L3,GSE1,SYT11,NEU4,TIE1,RBFOX2,RASD2,PRMT8,EIF4ENIF1,MEAF6,ZNF24,PARP11,PAK5" Pubmed 19034380 "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." Pubmed 4.37E-06 1.00E+00 1.17E-03 1.52E-02 14 37 "ERMN,CALM1,CLTB,SIRPB1,GFAP,HAPLN2,MBP,MOG,NEFM,OMG,PPP3CA,RNH1,SPTAN1,VSNL1" Pubmed 16923961 Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "ALCAM,CACNA2D1,CDH8,TUBB3,KCND2,NEUROD1,ROBO1,MYT1L,SYT1" Pubmed 21518438 Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "DDX3Y,HDAC9,EDIL3,FGFR3,ADAM22,P2RX7,PKD1,SOX6,CPEB3" Pubmed 29229865 Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "ANKRD13B,FOXG1,NUCB1,GPSM2,PRKCZ,CCDC88A,TJP1,PARD3,VANGL2" Pubmed 19258013 Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "OLIG2,GFAP,NKX2-2,PAX6,RELN,PTCH1,DBX2,SLIT1,SULF2" Pubmed 23999003 "SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation." Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "CPNE5,CPNE6,RIMS2,SYT3,SYT17,CPNE9,RIMS1,SYT1,SYT4" Pubmed 18184563 Members of the miRNA-200 family regulate olfactory neurogenesis. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "ASCL1,LHX2,ELAVL3,ELAVL4,FOXG1,GNAO1,NCAM1,NEUROD1,DICER1" Pubmed 22021915 A subpopulation of dorsal lateral/caudal ganglionic eminence-derived neocortical interneurons expresses the transcription factor Sp8. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "CALB2,OLIG2,TBR1,GFAP,NPY,PAX6,RELN,SOX6,SST" Pubmed 8221886 Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "ASCL1,TUBB3,STMN2,KIT,KITLG,NCAM1,NTRK2,PRPH,RET" Pubmed 19138174 "Channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics." Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "CAMK2A,CAMK2B,GDA,BAIAP2,TUBA1C,PPP3CA,PRKCB,TUBB2A,TUBA1A" Pubmed 15456728 The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity. Pubmed 4.48E-06 1.00E+00 1.19E-03 1.54E-02 9 16 "ASCL1,LHX2,TUBB3,GAP43,GNAL,STMN2,NCAM1,NCAM2,NEUROD1" Pubmed 21525287 "Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus." Pubmed 4.51E-06 1.00E+00 1.20E-03 1.55E-02 21 74 "BMP7,LHX2,DLX1,OLIG2,ZIC4,TUBB3,SOX21,LMO1,POU3F2,PTCH1,RFX3,RORB,RXRA,RXRG,SMARCD3,SOX2,SOX5,TCF7L2,TCF12,NR2E1,ZIC3" Pubmed 16951258 The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Pubmed 4.58E-06 1.00E+00 1.21E-03 1.57E-02 12 28 "CCK,CDH2,CHGA,INSM1,NEUROD1,NKX2-2,PCSK1,PCSK2,ARX,SST,SYP,TAC1" Pubmed 20816195 Analyses of shared genetic factors between asthma and obesity in children. Pubmed 4.62E-06 1.00E+00 1.22E-03 1.58E-02 16 47 "ADRA1B,ADRB2,DPP10,STK33,IL33,SH2B1,DGKG,NEGR1,PDE4D,KCTD15,FTO,PTPRD,ROBO1,FAIM2,CHST8,CRB1" Pubmed 20125193 Common genetic variation and performance on standardized cognitive tests. Pubmed 4.75E-06 1.00E+00 1.26E-03 1.62E-02 19 63 "NRXN3,FAM135B,ATL1,NCALD,NEK6,ACSS1,GRIK4,MAP4K5,TNFAIP8L3,BACH2,HTR2A,LINC01750,MDGA2,RIMS1,PLCB1,CAMTA1,WWC1,CSMD1,PARP11" Pubmed 23824909 Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Pubmed 5.17E-06 1.00E+00 1.31E-03 1.69E-02 64 374 "CPNE2,ABAT,AK2,PLA2G6,DPP10,API5,RASL11B,BID,AIFM1,LRBA,PPT2,NECTIN3,TRIM69,ECE2,AIF1L,ELMO1,FAM107B,DLG3,PDCD6IP,SORBS3,COPS4,SH3YL1,EVL,EFCAB2,APOPT1,GAB1,GFRA1,SPIN1,GNAO1,LPAR4,MUM1,HNRNPK,HSPA1L,HSP90AA1,SCIN,METTL21A,STMN1,MAP4,DBNL,NAP1L1,NASP,NDP,OLA1,ZNF655,PLEC,ZNF426,PSAT1,MED1,MAPK7,PSMA6,S100B,COPZ1,FUZ,PBLD,FAM168A,ALG1,PCDHGB2,TPD52,WBP2,SSBP2,TOM1L2,WIPF1,CFAP298,NETO1" Pubmed 19373938 Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "AQP4,DMD,DTNA,GFAP,ITGAM,LAMA2,MAG,MBP,LAMA1,PTPRZ1,S100B" Pubmed 26857994 Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "CLTC,NBEA,MEIS2,NTRK2,NTRK3,RET,SOX2,SOX10,SYT1,UCHL1,MEIS3" Pubmed 15858069 Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "FZD9,LHX2,CRYM,EMX2,EPHB1,TUBB3,FOXG1,GRIK4,KITLG,PROX1,RELN" Pubmed 28760865 Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "CALB1,CALB2,ISPD,EDIL3,GFAP,GLUL,L1CAM,PRKCB,PRKCG,SLC6A9,SLC17A7" Pubmed 22157746 CPEB2-eEF2 interaction impedes HIF-1? RNA translation. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "COPS7A,C2CD2L,CPEB2,SORBS3,BSCL2,GAA,GABBR1,NECAB2,PUF60,CPEB3,TUBA1A" Pubmed 24391519 The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "NUMB,NEURL1,NUMBL,MAML1,HEYL,RBPJ,HES5,PROX1,SOX2,HEY1,HEY2" Pubmed 17880938 Six1 is essential for early neurogenesis in the development of olfactory epithelium. Pubmed 5.19E-06 1.00E+00 1.31E-03 1.69E-02 11 24 "ASCL1,LHX2,EBF1,TUBB3,GAP43,STMN2,HES5,NCAM1,NEUROD1,PAX6,SOX2" Pubmed 19713751 Proteomic analyses of native brain K(V)4.2 channel complexes. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DPP10,DPP6,KCND2,KCNIP3,KCNIP2,KCNIP1" Pubmed 12351730 Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "ACHE,CALB2,TUBB3,MAP2,NEFH,FZD3" Pubmed 22376909 Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DLX1,EGFR,ERBB4,NRG3,GAD1,RELN" Pubmed 9341169 Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "AMPH,BIN1,SYNJ1,DNM1,SH3GL2,SH3GL3" Pubmed 15758185 "Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex." Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "LDB2,LHX2,EMX2,TBR1,NEUROD1,PAX6" Pubmed 16823490 Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in mice. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "ADCYAP1R1,GFAP,PDGFRA,SLC1A3,SOX10,IFT88" Pubmed 21491541 Fgfr3 regulates development of the caudal telencephalon. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "OLIG2,FGFR3,TBR1,GAD1,GFAP,PAX6" Pubmed 3402356 A survey of neurological mutant mice. II. Lipid composition of myelinated tissue in possible myelin mutants. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "QKI,GALC,LAMA2,MBP,PLP1,PMP22" Pubmed 27052163 PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CANX,DLG4,PRRT2,SNAP25,SYP,SYT1" Pubmed 12764029 Increase in reelin-positive cells in the marginal zone of Pax6 mutant mouse cortex. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,CALB2,EMX2,TBR1,PAX6,RELN" Pubmed 16820005 Characterization of TROY-expressing cells in the developing and postnatal CNS: the possible role in neuronal and glial cell development. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "TUBB3,GFAP,MAP2,MSI1,NCAM1,TNFRSF19" Pubmed 7671305 "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein." Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "AP2A1,AP2A2,STX1A,SYN1,SYP,AP3B2" Pubmed 10542231 The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "AMPH,SYNJ1,DNM1,DNM2,SH3GL2,SH3GL3" Pubmed 22099461 Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "SYNJ1,DNM1,DNM2,SH3GL2,SH3GL3,TMEM163" Pubmed 26443267 Imbalance of excitatory/inhibitory synaptic protein expression in iPSC-derived neurons from FOXG1(+/-) patients and in foxg1(+/-) mice. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DLG4,FOXG1,GABRA1,GAD1,GRIA1,SLC17A7" Pubmed 14999075 Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,FABP7,TUBB3,TBR1,NEFH,SLC1A3" Pubmed 11414789 Platelet-derived growth factor receptor-alpha in ventricular zone cells and in developing neurons. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,TUBB3,GFAP,MAP2,PDGFRA,SYP" Pubmed 11140673 Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DLG4,CACNG2,GRIA1,GRIA2,GRIA4,GRIN1" Pubmed 18066062 Ciliary proteins link basal body polarization to planar cell polarity regulation. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "FOXG1,KIF3A,MYO6,FZD3,VANGL2,IFT88" Pubmed 10729834 Pairing SOX off: with partners in the regulation of embryonic development. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "SOX6,SOX1,SOX2,SOX3,SOX5,SOX10" Pubmed 10844022 Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DYNLL1,DLGAP1,DLG2,DLG4,MYO5A,SHANK2" Pubmed 22404429 "Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons." Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DBN1,TUBB3,PRPH,STX1B,STX1A,RUSC1" Pubmed 15091338 Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "SLIT2,L1CAM,ROBO1,ROBO2,SLIT1,CNTN2" Pubmed 16223892 "Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage." Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "ABCD2,APP,CALB1,GFAP,NEFH,SYP" Pubmed 9852577 Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "KCNA1,KCNA2,KCNA4,KCNB1,KCNC1,KCNC2" Pubmed 15381924 Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,GPHN,GAD2,DISC1,GFAP,MAP2" Pubmed 28431046 BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DCT,FABP7,KIT,MITF,SMARCA4,SOX10" Pubmed 21688288 Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,SLIT2,TUBB3,ROBO1,ROBO2,SLIT1" Pubmed 20843900 Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Pubmed 16857183 Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "DCT,TUBB3,GFAP,PAX6,SOX2,SOX10" Pubmed 9016303 Glutamate receptors in cortical plasticity: molecular and cellular biology. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3" Pubmed 21280162 Prospective identification and isolation of enteric nervous system progenitors using Sox2. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "ELAVL3,ELAVL4,TUBB3,GFAP,SOX2,SOX10" Pubmed 19710317 Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,CALB2,MAP2,RELN,VLDLR,LRP8" Pubmed 10398046 Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "SV2B,SV2A,DNM1,DNM2,NCAM1,STX1A" Pubmed 9651535 Glutamate receptors: brain function and signal transduction. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3" Pubmed 10719888 Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "OLIG1,OLIG2,NKX2-2,PAX6,PDGFRA,PLP1" Pubmed 11148209 The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "BCAS1,DYNLL1,DLGAP1,DYNC1I1,ZMYND11,MYO5A" Pubmed 14757526 Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,NCAN,TUBB3,RELN,PTPRE,PTPRZ1" Pubmed 22337885 TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "PLPPR4,PTGR2,PLPPR3,TRIM67,UBC,TRIM9" Pubmed 29252214 Microglia ablation alleviates myelin-associated catatonic signs in mice. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CADPS,DLG2,DLG4,MBP,PLP1,AMBRA1" Pubmed 11856531 Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CALB1,ETV1,MAP2,RELN,VLDLR,LRP8" Pubmed 10712642 "Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain." Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "SV2A,STMN1,MAP2,SNAP25,STX1A,SYP" Pubmed 14592966 Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization. Pubmed 5.27E-06 1.00E+00 1.31E-03 1.69E-02 6 7 "CNTNAP1,CNTN1,KCNA1,KCNA2,KCNAB1,RTN4" Pubmed 24403153 Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex. Pubmed 5.28E-06 1.00E+00 1.31E-03 1.69E-02 10 20 "FGF17,CALB2,LHX2,DLX1,ETV1,TBR1,GRM1,MAP2,PAX6,RELN" Pubmed 18448648 Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. Pubmed 5.28E-06 1.00E+00 1.31E-03 1.69E-02 10 20 "CALB2,ETV1,TBR1,GAD1,RELN,FEZF2,RORB,ZIC1,ZIC2,ZIC3" Pubmed 27469598 Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Pubmed 5.28E-06 1.00E+00 1.31E-03 1.69E-02 10 20 "APC,CALB1,OLIG1,OLIG2,FABP7,TBR1,GFAP,PAX6,PDGFRA,POU3F2" Pubmed 29961574 Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Pubmed 5.28E-06 1.00E+00 1.31E-03 1.69E-02 10 20 "SLIT2,TUBB3,TBR1,GRM1,HES5,PAX6,RELN,ROBO1,ROBO2,SLIT1" Pubmed 26798014 Oligodendrocyte precursors migrate along vasculature in the developing nervous system. Pubmed 5.28E-06 1.00E+00 1.31E-03 1.69E-02 10 20 "APC,OLIG1,OLIG2,FABP7,MBP,NKX2-2,PDGFRA,PLP1,SLC1A3,WNT7A" Pubmed 12107411 "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts." Pubmed 5.36E-06 1.00E+00 1.33E-03 1.72E-02 18 58 "DGCR6,SLC25A25,GRAMD1B,CEP126,AQP4,ANKRD35,ST18,USP16,TPPP3,THYN1,TAGLN3,PNMA8A,MIR124-2HG,SP4,UNC5B,SYP,CELF4,SLC17A7" Pubmed 26988119 A cellular and molecular mosaic establishes growth and differentiation states for cranial sensory neurons. Pubmed 5.69E-06 1.00E+00 1.41E-03 1.82E-02 13 33 "ASCL1,LHX2,ELAVL3,ELAVL4,TUBB3,FGFR1,HMX1,NEUROD1,NTRK2,NTRK3,PAX6,RET,SOX10" Pubmed 26901059 ?-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development. Pubmed 5.69E-06 1.00E+00 1.41E-03 1.82E-02 13 33 "CHGB,GCK,KCNJ11,SYTL4,NEUROD1,NKX2-2,NPY,PAX6,PCSK1,PCSK2,POU3F4,ARX,ABCC8" Pubmed 28228269 Diverse Central Projection Patterns of Retinal Ganglion Cells. Pubmed 5.69E-06 1.00E+00 1.41E-03 1.82E-02 13 33 "CALB2,CCK,SLC32A1,DRD1,ERBB4,ETV1,GAD2,SDK2,SST,TAC3,CUX2,SLC17A6,NETO1" Pubmed 20571754 Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Pubmed 5.70E-06 1.00E+00 1.41E-03 1.82E-02 21 75 "ADCY5,APOC1,APOC2,LGR5,MADD,STK33,SH2B1,CRY2,DGKB,HMGCR,NEGR1,IGF1,KCNJ11,PCSK1,KCTD15,FTO,PLTP,PROX1,SARS,TCF7L2,AGMO" Pubmed 27325702 Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration. Pubmed 5.70E-06 1.00E+00 1.41E-03 1.82E-02 21 75 "APP,ATP6V0A1,DCAF5,RNF14,DCAF8,COPS7A,SV2B,SV2A,COPS4,COPS8,MAPT,PSMD13,RAB3A,SNAP25,HECW1,SYN1,SYN2,SYT1,FBXL16,UBE3A,SLC17A7" Pubmed 24667918 Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction. Pubmed 5.75E-06 1.00E+00 1.42E-03 1.83E-02 26 105 "SERPINA3,AGT,CA12,CH25H,CD38,CHI3L2,FHL5,CP,SORBS1,SULT1C4,GGT5,PPARGC1A,IGFBP1,KCNB1,NRCAM,PCSK5,GPR85,ELOVL2,RORB,SELL,SMOC1,SLC19A3,TF,SLC13A3,SCG2,PCDH15" Pubmed 16829211 Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Pubmed 6.15E-06 1.00E+00 1.50E-03 1.94E-02 19 64 "NRP2,CDH2,CDO1,PCOLCE2,CGREF1,GSN,MEF2C,SNX10,PLTP,PTCH1,PTH1R,PTPN13,PTPRZ1,PRR5L,SMPD3,RASA3,SPP1,UNC5B,SATB2" Pubmed 18279309 Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,DLG4,GLUL,SYP,PCDHB15,PCDHB6,PCDHB4,PCDHB3" Pubmed 18937294 Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ADRB2,ARRB2,CHRNA4,DRD1,HTR2A,SULF2,SYT1,NAV2" Pubmed 17141158 Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,STK33,CDC25B,DLL3,INSM1,POU3F2,POU3F4,FBXW7" Pubmed 9876181 Mash1 regulates neurogenesis in the ventral telencephalon. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,LHX2,DLX1,DLL3,GAD1,STMN2,HES5,PENK" Pubmed 16873583 "Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes." Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,CALB2,ETV1,FABP7,TUBB3,RELN,RORB,CUX2" Pubmed 25852085 Inhibition of type 5 phosphodiesterase counteracts ?2-adrenergic signalling in beating cardiomyocytes. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ADRB2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B" Pubmed 17391983 BMP signaling mutant mice exhibit glial cell maturation defects. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "BMPR1B,OLIG2,GALC,GFAP,MBP,PDGFRA,PLP1,S100B" Pubmed 10908577 HIV-1 rev depolymerizes microtubules to form stable bilayered rings. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2A,TUBB1,TUBA1A" Pubmed 25680202 Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "MYRF,OLIG1,OLIG2,MBP,NKX2-2,PLP1,SLC1A3,SOX10" Pubmed 22699903 The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "DLX1,TUBB3,FOXG1,GAD1,HES5,MAP2,RELN,SST" Pubmed 20144603 Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "DCT,OLIG2,FABP7,TUBB3,MBP,MITF,SOX8,SOX10" Pubmed 18641643 "Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation." Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "BSN,CALB1,DMD,GRIK2,PRKCB,PRKCG,S100B,STX1A" Pubmed 20620871 Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,ETV1,NOVA1,NOVA2,POU3F2,RELN,RAP1GAP,LRP8" Pubmed 21315259 Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CDH2,TBR1,GAD1,GAD2,MAP2,NEFH,RELN,CUX2" Pubmed 12561075 "Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding." Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB2,LHX2,EMX2,TUBB3,TBR1,L1CAM,RELN,RORB" Pubmed 11543631 Genomic analysis of synaptotagmin genes. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ESYT2,SYT13,SYT6,SYT15,SYT3,SYT9,SYTL2,SYT11" Pubmed 27923395 Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,CHGA,STMN2,RBPJ,TAGLN3,NHLH1,PAX6,CNTN2" Pubmed 17409253 Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,CALB2,FOXG1,TBR1,GAD1,GFAP,L1CAM,CNTN2" Pubmed 14622142 Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,DLG4,TUBB3,GFAP,MAP2,SHANK2,SYN1,SYP" Pubmed 18459960 Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,CALB2,TUBB3,ZFYVE27,MAP2,NKX2-2,PAX6,PRPH" Pubmed 14623284 Yeast two-hybrid screens implicate DISC1 in brain development and function. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "PPFIA4,KALRN,DMTN,KATNAL1,DISC1,MGAT3,SMARCE1,SPTAN1" Pubmed 23534961 Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "NRP2,SLIT2,DCC,ROBO1,ROBO2,SLIT1,ROBO3,SEMA3B" Pubmed 19332558 The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "NRP2,CALB1,CALB2,CELSR3,ERBB4,TUBB3,MAP2,SST" Pubmed 11456441 Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,VAX2,DCT,L1CAM,MITF,NEUROD1,PAX6,PTCH1" Pubmed 20859245 Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "GAD1,GRIA1,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRM1" Pubmed 14627641 Tlx controls proliferation and patterning of lateral telencephalic progenitor domains. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,LHX2,ETV1,PPP1R1B,TBR1,NKX6-2,PAX6,NR2E1" Pubmed 23434913 Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "ASCL1,CALB1,CDH2,TUBB3,SCRT2,PAX6,SOX2,TJP1" Pubmed 15673434 "A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins." Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CASK,CAMK2A,INA,DLGAP1,DLG4,SHANK1,GRIA1,SPTAN1" Pubmed 15972963 Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin. Pubmed 6.29E-06 1.00E+00 1.50E-03 1.94E-02 8 13 "CALB1,CALB2,CNTN1,GAP43,L1CAM,SST,TAC1,TACR1" Pubmed 24165879 Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Pubmed 6.30E-06 1.00E+00 1.50E-03 1.94E-02 14 38 "RASL11B,COX4I1,DBI,TIAM2,EDIL3,PPP1R1B,NSG2,TBR1,NXPH3,IGFBPL1,NEUROD1,NEUROD2,SLA,SATB2" Pubmed 25613138 HIV-1 subtypes B and C Tat differentially impact synaptic plasticity expression and implicates HIV-associated neurocognitive disorders. Pubmed 6.30E-06 1.00E+00 1.50E-03 1.94E-02 14 38 "CAMK2G,EGR3,GABRA5,GRIA1,GRIN1,GRIN2C,GRIN2D,GRM3,GRM5,GRM7,SYNPO,NOS1,RAB3A,SIRT1" Pubmed 23597562 Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Pubmed 6.48E-06 1.00E+00 1.54E-03 1.99E-02 15 43 "AGT,CCK,CCKBR,EDN1,EDNRA,EDNRB,EGFR,CALCRL,FGFR1,GALR1,OPRL1,PENK,TAC1,TAC3,TACR1" Pubmed 14760703 Proteomic identification of brain proteins that interact with dynein light chain LC8. Pubmed 6.48E-06 1.00E+00 1.54E-03 1.99E-02 15 43 "DYNLL1,HIP1R,CS,DLG4,GRIN3A,DNM2,GPHN,GLUL,MARK3,MTR,PFKP,MAST1,PARD3,TUBB2A,CLIP2" Pubmed 24014668 Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants. Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "NRP2,LHX2,TBR1,GBX2,HPCA,PAX6,SEMA5B,PTCH1,SLC6A7,SOX5,CNTN2,SATB2" Pubmed 26758845 Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1. Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "DCC,DLG4,OLIG2,ITGAM,MAPT,NKX2-2,NTRK2,NTRK3,RET,SNCA,STX1A,STXBP1" Pubmed 22514301 c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "CCK,EBF1,GABRA5,GFRA2,TLX1,MAPT,NEFH,NTRK2,NTRK3,RET,RORB,SLC17A7" Pubmed 26839365 The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord. Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "SLC32A1,OLIG2,TUBB3,GAD1,GAD2,GFAP,NFIA,NKX2-2,PAX6,SOX2,SST,SLC17A6" Pubmed 21998595 "Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry." Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "SYN3,ZFAT,LCORL,SMIM29,ARSE,DCLK1,ATF7,ENPP2,CCDC88A,TNS1,ZBTB38,ADAMTSL3" Pubmed 11156964 HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway. Pubmed 7.13E-06 1.00E+00 1.67E-03 2.15E-02 12 29 "PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PIK3C2A,PIK3CD,PIK3R1" Pubmed 23375831 In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Pubmed 7.26E-06 1.00E+00 1.67E-03 2.15E-02 32 145 "MAP4K3,ARNTL,RASL11B,LGI1,CNN3,ENTPD4,CNTNAP2,DLC1,MTHFD2,CACFD1,FAM107A,HMGCL,SCIN,MYH7,MYL3,SERPINI1,PKD1,SCHIP1,SEPT4,WLS,RXRG,DGLUCY,ABLIM3,EPC1,SMARCE1,TIMP4,TNNT1,LRTM2,LYPD6,ZFAND5,ACTR3B,NETO2" Pubmed 18650339 Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CNTNAP1,OLIG2,TUBB3,L1CAM,MAP2,NEFH,CNTN2" Pubmed 19240213 Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "DLG4,ERBB2,ERBB4,TBR1,GFAP,GRIN1,LAMA2" Pubmed 10037800 From head to toes: the multiple facets of Sox proteins. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "SOX6,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11" Pubmed 27170656 Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,CALB2,CELSR3,PAX6,RELN,SLC17A6,FZD3" Pubmed 21491429 PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-? activation in mouse models of Down syndrome. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,CALB2,CAMK2A,CAMK2D,CAMK2G,TUBB3,MAP2" Pubmed 23828756 Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "FABP7,GFAP,GLUL,PROX1,RELN,S100B,SLC1A2" Pubmed 19616129 Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,TUBB3,GLUL,PAX6,PRKCG,STX1A,PRDM8" Pubmed 26705332 Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CDH8,LYPD1,EMX2,TBR1,RORB,UNC5D,CUX2" Pubmed 1383027 Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCND1" Pubmed 18291358 Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "HEYL,HES5,MYO6,PROX1,SOX2,HEY1,HEY2" Pubmed 12223406 MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "TUBB3,MAP2,MAPK3,MAPK8,MAPK9,MAPK12,MAP3K12" Pubmed 15748846 GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,GAD1,GAD2,GFRA1,GFRA2,NCAM1,RET" Pubmed 21940705 Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "LHX2,EPHA5,LMO1,PBX1,SATB1,MYT1L,CPNE4" Pubmed 19071123 Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "MPDZ,MAGI1,TJP2,MPP6,MAGI3,TJP1,GOPC" Pubmed 22879516 Fate-restricted neural progenitors in the mammalian cerebral cortex. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "TBR1,GAD1,GAD2,NEFH,PAX6,SATB2,CUX2" Pubmed 27466336 "Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons." Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CPLX2,CPLX1,STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 27618674 Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "ASCL1,CALB2,CCK,ETV1,GAD2,NOS1,SST" Pubmed 14602683 Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "OLIG1,OLIG2,MBP,NKX2-2,PDGFRA,PLP1,SOX10" Pubmed 20739404 The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,TUBB3,GFAP,MYH6,MYH7,SOX10,THRA" Pubmed 23862023 Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "ELAVL3,ELAVL4,FABP7,TUBB3,NCAM1,NPY,SOX10" Pubmed 22241837 Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,TUBB3,GFAP,STMN2,PROX1,SOX1,SYT4" Pubmed 11074448 Evidence for intrinsic development of olfactory structures in Pax-6 mutant mice. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "NRP2,CALB1,CALB2,EMX2,PAX6,ROBO2,SEMA3B" Pubmed 15385616 The Tlx gene regulates the timing of neurogenesis in the cortex. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB2,TUBB3,SALL3,MAP2,PAX6,SALL1,NR2E1" Pubmed 22173850 SPARC-like 1 (SC1) is a diversely expressed and developmentally regulated matricellular protein that does not compensate for the absence of SPARC in the CNS. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "SPARCL1,AQP4,FABP7,TUBB3,TBR1,GFAP,S100B" Pubmed 24027281 Endothelial VEGF sculpts cortical cytoarchitecture. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,CALB2,TBR1,CHL1,GAD1,GAD2,MAP2" Pubmed 25037921 Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CRYM,L1CAM,HCN1,PRKCG,FEZF2,SATB2,ZFPM2" Pubmed 22623663 Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CDH8,EMX2,TBR1,KITLG,ZIC1,ZIC2,ZIC3" Pubmed 22806269 CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,CALB2,TUBB3,GFAP,MBP,RELN,CDK5RAP2" Pubmed 16374517 Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "AGT,ATP2A2,PTK2B,MYH6,MYH7,NPPA,PTK2" Pubmed 21307234 Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "SLIT2,TBR1,GFAP,L1CAM,ROBO1,ROBO2,SLIT1" Pubmed 17420921 The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome. Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "NIPA1,ATL1,BSCL2,KIF5A,L1CAM,PLP1,SPART" Pubmed 16707115 "Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain." Pubmed 7.29E-06 1.00E+00 1.67E-03 2.15E-02 7 10 "CALB1,PSD2,GRIA1,GRM1,PSD,SYP,PSD3" Pubmed 25807483 Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Pubmed 7.37E-06 1.00E+00 1.68E-03 2.17E-02 24 94 "AP1B1,CC2D2A,SEMA6A,SLIT2,HECTD1,CCDC151,DNM2,EVL,GLDC,CNTRL,ADAMTS6,PCSK5,PDE2A,PKD1,MAPK7,QRICH1,RFX3,KIF7,ROBO1,FUZ,SMARCA4,WRN,ZBTB14,IFT88" Pubmed 23752268 The functional interactome landscape of the human histone deacetylase family. Pubmed 7.45E-06 1.00E+00 1.70E-03 2.20E-02 52 287 "ACADM,ADAR,ADD3,PWWP2A,MTA3,ZNF687,PHF12,MIER1,CCAR2,AIFM1,PLAA,ZNF521,NCOR1,NCOR2,APPL1,HDAC9,HDAC4,ELMSAN1,ZC3H11A,SEC16A,DNAJB6,FDFT1,NOP56,STAG2,MIER3,IPO5,PAXBP1,RCOR2,ZNF827,ZSCAN2,USP47,ARID4A,PUF60,RCOR3,RBM34,SON,TRERF1,MYCBP2,GSE1,SYNE2,ANKRD12,TBL1X,SIN3B,DICER1,HHIP,TMPO,TPM3,TPM4,ZMYND8,TFIP11,EMSY,FIP1L1" Pubmed 29799838 Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. Pubmed 8.39E-06 1.00E+00 1.91E-03 2.47E-02 13 34 "HIP1R,RGN,JAM2,YTHDC1,CNNM1,DNER,LRP1B,SLC11A2,PSAT1,SPATA7,TRPS1,ZNF711,PARP6" Pubmed 18625063 FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Pubmed 8.45E-06 1.00E+00 1.92E-03 2.48E-02 11 25 "FGF17,EMX2,TUBB3,FGFR1,FGFR3,TBR1,GAD1,MEF2C,MEST,PAX6,RELN" Pubmed 17185339 Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. Pubmed 8.45E-06 1.00E+00 1.92E-03 2.48E-02 11 25 "GABBR1,GNAO1,GNG3,GNG4,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,RGS4" Pubmed 9275178 Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Pubmed 8.45E-06 1.00E+00 1.92E-03 2.48E-02 11 25 "KIF6,KIF1A,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KIF7,KIF16B,KIF13A,KIF1B" Pubmed 18927156 Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner. Pubmed 8.45E-06 1.00E+00 1.92E-03 2.48E-02 11 25 "AXIN2,ASCL1,CDH2,OLIG1,OLIG2,GLI2,SMAD1,SMAD9,NKX2-2,PAX6,PTCH1" Pubmed 25142465 Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Pubmed 8.52E-06 1.00E+00 1.93E-03 2.49E-02 16 49 "AMH,SPAG9,HDAC4,ELAVL2,ERBB4,HPGDS,PTGDR2,KIT,NODAL,PDE3A,ARID4A,SALL1,TET1,CPEB4,SOX2,NR2C2" Pubmed 15592455 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Pubmed 8.56E-06 1.00E+00 1.94E-03 2.50E-02 57 326 "ACLY,ALK,KCNAB2,DDX3Y,BID,FUBP1,CARS,C1orf52,SEPT7,TJP2,CDC42BPB,ENTPD4,CTNND1,ZFYVE16,IST1,GIT2,KBTBD11,DNM1,DOCK2,DYRK1A,EEF1A2,HIPK3,EIF4G1,TNK2,EIF1,ENO2,TUBA1B,RACK1,BAIAP2,MPP6,GART,CRCP,RNPS1,NUDT21,EML4,TUBA1C,SYNPO,GIT1,DBNL,NUMA1,PFKP,PIK3R1,PKM,PLEC,RASA3,ELMO2,FNBP1,SRPK2,ERBIN,STXBP1,TACC1,DICER1,VAV1,TBC1D15,CFAP298,ZNF24,FXR1" Pubmed 27432908 Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Pubmed 8.64E-06 1.00E+00 1.94E-03 2.50E-02 131 931 "ACLY,AP2A2,HECW2,CASKIN1,CDC14B,STX16,MTMR9,DOCK11,DCAF5,MTMR3,MTMR2,RAB29,CANX,CBS,MTMR7,CDC25B,CLGN,DIS3L,RAB28,TPP1,QKI,CNN3,ARMC8,COX4I1,PNKD,CDC42BPB,CTNND1,GAPVD1,DCAF8,DCTN1,B3GAT3,MTX3,DMD,ACOT8,DTNA,DTNB,DUSP9,KCTD3,COPS4,DCTN4,FDFT1,POLR1B,CAP2,PCYOX1,VTI1B,DCTN2,COQ5,PNMA2,AHCYL1,MTHFD2,NFU1,DHRS4,COPS8,SPIN1,CBX1,OS9,ATE1,PTPN5,MAN1B1,ACOT7,DOCK7,GATD1,KIF2A,KPNA5,IPO5,KCTD6,DBNL,PCMT1,PDE4D,DUSP26,SSH1,TNPO2,PPP2R2B,PPP5C,MAPK3,MAPK4,MAPK8,MAPK9,CNNM2,CYBC1,PSMD13,MTMR10,PTPRE,PTPRN,PTPRO,RAB5B,RAP1GDS1,OXR1,SEC61A2,ELP2,AP1AR,SARS,SBF1,COPZ1,HSPA4L,AMBRA1,FBXO11,PPP4R3A,RBM34,GLT8D1,CAND2,ZBTB43,TROVE2,NCDN,GANAB,SUPT5H,NUDT10,ALG1,WWC1,FBXW11,MGRN1,TNS2,AHCYL2,SIRT1,ZFPM2,ARL10,MTMR14,TMEM9,TNS1,STXBP4,HSPBP1,RPL7L1,AMOT,UGT8,MTCH1,TBC1D15,XPO1,XRCC4,MFF,GOPC,MRPL47" Pubmed 27241892 Spatio-temporal expression of Sox genes in murine palatogenesis. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "SOX21,SOX8,SOX6,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11" Pubmed 23292680 Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "NRP2,SLIT2,EMX2,FOXG1,TBR1,GAD1,PAX6,RELN,SLIT1" Pubmed 10556054 Ebf1 controls early cell differentiation in the embryonic striatum. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "CALB1,CDH8,DLX1,EBF1,PPP1R1B,DLL3,GAD1,MAP2,RXRG" Pubmed 19439493 "Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1." Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "CALB1,CALB2,CAMK2A,ELAVL3,ELAVL4,GAD1,GFAP,PAX6,SLC17A6" Pubmed 22243746 Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathway. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "EFNA2,EFNA3,EFNB3,TUBB3,GRM2,GRM3,NEFH,POU3F4,SOX10" Pubmed 11498051 The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "CALB1,CALB2,EBF1,NTRK2,NTRK3,PRKCG,PRPH,RET,TAC1" Pubmed 1354644 A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "APC,CAMK2A,CSF1R,DCC,FGF1,GNAL,NR3C1,KIF5A,MBP" Pubmed 22090513 Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "TUBB3,GAD1,L1CAM,NEFH,POU3F2,MAPK8,CNTN2,SATB2,SLC17A6" Pubmed 26864488 Expression of Sox genes in tooth development. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "SOX21,SOX8,SOX6,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11" Pubmed 25535838 Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "APC,CALB1,CALB2,FABP7,GFAP,MAP2,NF1,MAPK3,ZIC1" Pubmed 26302206 Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "NRP2,SEMA3D,TUBB3,GAP43,MYO6,NEFH,SOX2,SYT1,SEMA3B" Pubmed 21562282 "N-myc controls proliferation, morphogenesis, and patterning of the inner ear." Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "CALB2,TUBB3,FOXG1,MYCN,MYO7A,NEUROD1,PROX1,SOX2,SOX10" Pubmed 26209645 "Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development." Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "MPDZ,TUBB3,PAX6,FAT4,SOX2,SATB2,TJP1,PARD3,VANGL2" Pubmed 21666133 Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "CDH8,FABP7,TUBB3,TBR1,MEF2C,PAX6,RELN,RORB,CUX2" Pubmed 24336726 The indirect role of fibroblast growth factor-8 in defining neurogenic niches of the olfactory/GnRH systems. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "ASCL1,NOG,ELAVL3,ELAVL4,TUBB3,SMAD1,SMAD9,PAX6,SOX2" Pubmed 23749646 Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons. Pubmed 8.70E-06 1.00E+00 1.94E-03 2.50E-02 9 17 "TUBB3,PPP1R1B,TBR1,HES5,NFIA,PAX6,FEZF2,SOX2,SATB2" Pubmed 17213182 Identification of genes related to Parkinson's disease using expressed sequence tags. Pubmed 8.95E-06 1.00E+00 1.99E-03 2.57E-02 21 77 "AQP4,CLTA,CREM,SIPA1L1,VCAN,STARD3NL,SEMA4D,TRAF3IP2,GGTA1P,GRIK3,FAM107A,CFAP126,DBNL,OCIAD1,RERGL,PAQR6,HES6,ASRGL1,DBNDD2,BAALC-AS1,CBX5" Pubmed 23863479 Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Pubmed 8.96E-06 1.00E+00 1.99E-03 2.57E-02 14 39 "AXIN2,CALB2,LHX2,CLU,FABP7,AMOTL2,GFAP,GRIK4,PAX6,PRKCZ,PROX1,RELN,SOX2,TJP1" Pubmed 19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Pubmed 8.96E-06 1.00E+00 1.99E-03 2.57E-02 14 39 "NCKAP5,FOXO3,MXI1,PCSK5,PDZRN4,RELN,SLC25A36,KCNIP1,SH3GL2,NUBPL,WDR7,CSMD1,ZIC1,CBLN2" Pubmed 22889411 "Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase." Pubmed 9.12E-06 1.00E+00 2.01E-03 2.60E-02 18 60 "ABR,ADRA1D,PKP4,KALRN,LRRC3B,CTNND2,LNX1,GRIN1,KCNA4,MDGA1,NRCAM,ABCB1,PDZRN4,SLC6A15,HUNK,PDZRN3,DOCK9,TSC2" Pubmed 27005988 "Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome." Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "CALB1,TBR1,GAD1,HES5,NEUROD2,PAX6,FEZF2,RORB,MESP1,SST" Pubmed 17409257 Plexin-B2 controls the development of cerebellar granule cells. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "SEMA6A,SEMA4G,CALB1,SEMA4D,GFAP,PAX6,SEMA4A,CNTN2,ZIC1,SLC17A6" Pubmed 28413018 PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "CA8,CALB1,PLAA,SV2A,GALR1,GFAP,AP4S1,SNAP25,UBC,VLDLR" Pubmed 20081193 The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "ASCL1,LHX2,OLIG2,FGFR1,FGFR3,FOXG1,MEST,PAX6,RELN,PTCH1" Pubmed 17644613 Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "AXIN2,ZEB2,EMX2,TUBB3,GRIK4,MAPK8,MAPK9,MAPK10,PROX1,SATB2" Pubmed 19820705 Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "ASCL1,NRP2,BMP7,LHX2,ETV1,FABP7,PAX6,ARX,SLC6A7,SATB2" Pubmed 20445055 Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "BMPR1B,CALB1,CALB2,ETV1,TUBB3,TBR1,SMAD1,SMAD9,FEZF2,RORB" Pubmed 15148151 Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families. Pubmed 9.21E-06 1.00E+00 2.01E-03 2.60E-02 10 21 "ATN1,FGF14,TMEM240,KCND3,PPP2R2B,PRKCG,ATXN1,ATXN2,ATXN7,TTBK2" Pubmed 18793656 "Kainate receptors: pharmacology, function and therapeutic potential." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 12827191 Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CACNA1A,CACNA1B,CACNA1E,NRXN1,NRXN2" Pubmed 11807022 A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CNTN1,L1CAM,NCAM1,NRCAM,CNTN2" Pubmed 22441692 JNK regulates the photic response of the mammalian circadian clock. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ARNTL,CLOCK,MAPK8,MAPK9,MAPK10" Pubmed 24120991 The tumor suppressor Chd5 is induced during neuronal differentiation in the developing mouse brain. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CALB1,CHD5,OLIG2,TUBB3,S100B" Pubmed 23664614 Three mechanisms assemble central nervous system nodes of Ranvier. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CNTNAP1,SPTBN4,VCAN,HAPLN2,BCAN" Pubmed 18923512 Neuroligins and neurexins link synaptic function to cognitive disease. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "NLGN4X,NRXN3,NRXN1,NRXN2,NLGN4Y" Pubmed 18582453 "Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "OLIG2,GAD1,GFAP,SLC1A3,TJP1" Pubmed 16421295 "Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ERMN,CNTNAP1,TUBB4A,AGFG1,MBP" Pubmed 25707359 Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ADAM23,CNTNAP2,ADAM11,ADAM22,CNTN2" Pubmed 21685723 JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CALB2,MAP2,MAPK8,PTK2,MAPK8IP3" Pubmed 22390626 PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ASCL1,OLIG2,PDGFRA,PDPK1,SOX10" Pubmed 25308109 Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "NEUROD1,RELN,UNC5D,VLDLR,LRP8" Pubmed 19053060 Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "PROM1,OLIG2,L1CAM,NCAM1,PLP1" Pubmed 20089912 "ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CNTNAP1,CNTNAP2,DLG2,DLG4,ADAM22" Pubmed 28687665 Mutation of the ?-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CALB2,GAD1,GFAP,NCAM1,TUBA1A" Pubmed 9736652 Embryonic expression of the myelin basic protein gene: identification of a promoter region that targets transgene expression to pioneer neurons. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CALB2,GFAP,MAPT,MBP,RELN" Pubmed 12963709 Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "KCNAB2,CNTNAP2,KCNA1,KCNA2,CNTN2" Pubmed 15578212 Regulation of cardiac shal-related potassium channel Kv 4.3 by serum- and glucocorticoid-inducible kinase isoforms in Xenopus oocytes. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "SGK2,KCND3,KCNIP2,SGK1,SGK3" Pubmed 9507007 "High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "NCAN,HMGB1,PTN,PTPRZ1,TNR" Pubmed 12223554 Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 28978485 An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GABRA1,GABRA2,GABRB3,GABRG2,LHFPL4" Pubmed 23076118 Developmental expression patterns of kainate receptors in the mouse spinal cord. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 12451131 Normal development of embryonic thalamocortical connectivity in the absence of evoked synaptic activity. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CALB1,CALB2,L1CAM,RELN,SNAP25" Pubmed 11867766 Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "SYN3,NOS1AP,NOS1,SYN1,SYN2" Pubmed 28063956 Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ZEB2,EDN3,EDNRB,TUBB3,SOX10" Pubmed 12764042 Choreography of early thalamocortical development. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "EMX2,L1CAM,PAX6,RELN,SNAP25" Pubmed 14985430 Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CDK5R1,CDK5R2,RELN,VLDLR,LRP8" Pubmed 23292839 "Expression of NCAM (CD56), chromogranin A, synaptophysin, c-KIT (CD117) and PDGFRA in normal non-neoplastic skin and basal cell carcinoma: an immunohistochemical study of 66 consecutive cases." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CHGA,KIT,NCAM1,PDGFRA,SYP" Pubmed 12473661 The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ARHGEF7,GIT2,PCLO,GIT1,PTK2" Pubmed 15834957 "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "CRMP1,DPYSL2,MAP2,MAPT,DPYSL5" Pubmed 23571214 BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "BEND6,TUBB3,GFAP,RBPJ,SOX2" Pubmed 15084255 The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "ROBO1,ROBO2,SLIT1,ROBO3,CNTN2" Pubmed 15572147 Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "NOS1,SOX8,S100B,SOX10,UCHL1" Pubmed 15939089 Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "FZD9,CALB1,CALB2,GFAP,MAP2" Pubmed 23684581 Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "TUBB3,GFAP,MYO6,MYO7A,SOX10" Pubmed 28647557 KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "SLC12A5,SV2A,SLC12A6,NEFH,SLC12A2" Pubmed 8288598 "Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies." Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIA1,GRIA2,GRIK2,GRIK4,GRIK5" Pubmed 9593973 Development of laminar distributions of kainate receptors in the somatosensory cortex of mice. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 18358623 Molecular determinants of kainate receptor trafficking. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 9466455 Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum. Pubmed 9.49E-06 1.00E+00 2.01E-03 2.60E-02 5 5 "GRIA1,GRIA4,GRIK2,GRIK3,GRIK5" Pubmed 16055720 WW domains provide a platform for the assembly of multiprotein networks. Pubmed 1.02E-05 1.00E+00 2.16E-03 2.79E-02 33 154 "ARID1A,AP2A1,APBB1,GAS7,CDK11B,SRSF11,DDX46,G3BP2,DNM2,ABI1,SRRM1,EVL,RAPGEF6,NCKAP1,TCERG1,RNPS1,HTATSF1,NUDT21,NCKAP1L,HNRNPK,CHAMP1,PKM,MED1,SFPQ,DHX30,SMARCC2,SMARCE1,SPART,WBP2,WIPF1,SF1,FIP1L1,WIPF2" Pubmed 24501781 Leukodystrophy Overview Pubmed 1.03E-05 1.00E+00 2.18E-03 2.82E-02 17 55 "ADAR,ASPA,CSF1R,EARS2,TUBB4A,GALC,GFAP,PLP1,POLR2F,PEX2,PEX5,SCP2,PEX26,SOX10,MLC1,HEPACAM,GJC2" Pubmed 18854154 Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. Pubmed 1.06E-05 1.00E+00 2.23E-03 2.89E-02 51 283 "RBM10,ARID1A,OSBPL6,MPDZ,MYRF,NUMBL,CLTA,AHCTF1,CLOCK,CLIP3,OSBPL3,CYBB,MYEF2,DNM2,MRPL10,RTN3,ZCCHC17,CGREF1,NCKAP1,RNPS1,GPT2,B4GALNT4,TPPP,KIF3A,HMGB1,KCNJ11,MAP4,MAT2A,MPP2,EXOSC10,PPP2R5E,PTPRN2,NUDT11,RNH1,RMI1,ATXN2,DOCK10,ST3GAL3,CEP68,GANAB,STXBP1,ATMIN,CDH22,R3HDM1,TTC3,UBE2H,DPYSL5,PRDM10,KAT6A,NUP214,FXR1" Pubmed 22711842 Wnt/?-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Pubmed 1.08E-05 1.00E+00 2.28E-03 2.94E-02 12 30 "AXIN2,BMP7,NOG,HEYL,RBPJ,SMAD1,SMAD9,MEF2C,SMARCD3,MESP1,HEY1,HEY2" Pubmed 19401682 High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. Pubmed 1.08E-05 1.00E+00 2.28E-03 2.94E-02 12 30 "FMNL2,OSBPL6,PLXNA4,DOCK4,RAPGEF4,ZNF385B,KCND2,ING3,RELN,CSRNP3,SCN2A,CUX2" Pubmed 19054571 Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Pubmed 1.08E-05 1.00E+00 2.28E-03 2.94E-02 12 30 "ADAM15,SEMA3D,SEMA6C,ADAM28,WIF1,ADAM22,NEFH,RELN,PCDHA3,WNT7A,FZD3,RTN4" Pubmed 9714600 The AP-3 complex: a coat of many colours. Pubmed 1.08E-05 1.00E+00 2.28E-03 2.94E-02 12 30 "AP2A1,AP2A2,AP1B1,AP1M1,AP4M1,BLOC1S6,AP4B1,AP4S1,HPS5,AP4E1,HPS4,AP3B2" Pubmed 20111592 RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors. Pubmed 1.08E-05 1.00E+00 2.28E-03 2.94E-02 12 30 "ASCL1,USH1C,FGFR3,FOXM1,IGF1,KCND2,KCNJ10,MBP,MEF2C,MYO7A,MAPK3,PROX1" Pubmed 24024966 Genome-wide association study of chronic periodontitis in a general German population. Pubmed 1.09E-05 1.00E+00 2.28E-03 2.95E-02 24 96 "ACTN1,ACTN2,SEMA6A,ERC2,NRSN1,PDCD6IP,FAM135B,GRIK1,PTPRT,KCNJ16,LRP1B,CCDC13,LRP12,RIT2,ROBO2,RYR3,SCN2A,NLGN1,SNRPN,KDM4B,NKAIN2,SS18,CSMD1,RGMA" Pubmed 23503679 Protein interaction discovery using parallel analysis of translated ORFs (PLATO). Pubmed 1.11E-05 1.00E+00 2.34E-03 3.02E-02 21 78 "RIMS2,E2F6,FSD1L,TUBB4A,HBS1L,PRUNE2,RASSF8,ARHGAP19,HNRNPK,HTR2A,LAMP2,ADAM22,SCG3,PRKCB,KHDRBS2,RDX,SLC12A4,ZNF423,PLEKHH2,CFAP298,ZNF189" Pubmed 26831064 CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly. Pubmed 1.15E-05 1.00E+00 2.41E-03 3.11E-02 78 494 "ACLY,OGT,TNRC6C,CCAR2,BARD1,BLM,CAMK2D,SPAG9,SEPT7,LRRFIP1,COPB2,CLTC,RCHY1,AKAP12,SEC24C,MATR3,DCTN1,HP1BP3,SEC16A,PDCD6IP,DYRK1A,EEF1D,EIF4G1,TUBB3,RACK1,PRMT5,SEC24B,SEC23B,SYNCRIP,FLNC,NOP56,PDLIM5,SEPT9,GART,TNRC6A,TUBA1C,ATXN2L,HNRNPK,HSPA1L,HSP90AA1,IPO5,MAP4,MOV10,NACA,HNRNPM,NAP1L1,NUMA1,PCMT1,PFKP,PKM,PLEC,EXOSC10,PSMD13,ZYG11B,MYH14,PCMTD2,RPL15,CLIP1,SFPQ,TRA2B,HSPA4L,CHD9,SEC31A,SMARCA4,SMARCC2,PALLD,ERC1,SPTAN1,ITPRID2,STAU1,GANAB,GPR161,TP53BP1,XPO1,CSDE1,HNRNPA3,NUP214,AAAS" Pubmed 29107558 ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Pubmed 1.26E-05 1.00E+00 2.63E-03 3.40E-02 14 40 "DGKD,ATP1A1,COL11A2,CTNND1,EPB41,MYO7A,OCRL,CLDN11,PROX1,LIMCH1,SOX2,GANAB,HEY1,HEY2" Pubmed 23673330 Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS. Pubmed 1.26E-05 1.00E+00 2.63E-03 3.40E-02 14 40 "BRAP,KSR1,CALB1,CALB2,DCTN1,TUBB3,GFAP,NKX2-2,KSR2,PAX6,MAPK3,CLIP1,SOX2,TMEM163" Pubmed 22321011 Protein phosphatase 1? interacting proteins in the human brain. Pubmed 1.28E-05 1.00E+00 2.68E-03 3.46E-02 19 67 "CEP126,ZFYVE9,CLTC,MAP4K4,CNTN1,AATK,SNCAIP,PHACTR3,SLC45A1,FRMPD4,DCTN1,CEP170,NDP,ZNF827,GLIPR1L2,STAU1,KANK1,TP53BP2,JPH3" Pubmed 24366813 Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. Pubmed 1.28E-05 1.00E+00 2.68E-03 3.46E-02 49 270 "LRCH2,CASK,DYNLL1,AZGP1,MPDZ,BTRC,ZFYVE9,COL4A5,FGFR1OP2,RASSF2,EPB41L1,EPB41L2,SRRM1,PRMT5,AMOTL2,MPP6,RAPGEF6,RNPS1,TUBA1C,GSN,GUCY1A2,GUCY1B1,RASSF8,FRMD5,FRMD3,DOCK7,MPP2,PTOV1,NRCAM,NUMA1,A2ML1,STRN3,PPP3CB,PRKCZ,PTPN13,MCMBP,HSPA4L,PPP1R9A,EPB41L3,ERBIN,KANK1,WWC1,FBXW11,PARD3,TP53BP2,WBP2,CADM1,AMOT,FRMD6" Pubmed 21423176 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation. Pubmed 1.29E-05 1.00E+00 2.70E-03 3.49E-02 51 285 "ACTN1,ADD1,ALCAM,CASK,NUMB,STX16,DST,ARHGEF7,CD81,ARHGEF2,CDC42,CDH2,ARHGAP22,CLTC,CNN3,AKAP12,GIT2,CD99L2,DNM2,PDCD6IP,EGFR,SORBS3,EPB41L2,FHL1,FLNC,FLT1,NCKAP1,FERMT2,GSN,PACSIN2,HNRNPK,DOCK7,ITGAV,JAK1,L1CAM,LIMS1,GIT1,LAYN,DDR2,PLEC,RDX,RPL38,LIMS2,PALLD,NFASC,MPRIP,TNS2,TNS1,TPM4,SYNPO2,FLRT2" Pubmed 15164054 The DNA sequence and comparative analysis of human chromosome 10. Pubmed 1.32E-05 1.00E+00 2.73E-03 3.52E-02 59 346 "ADARB2,SORCS1,GPR158,GOLGA7B,GPAM,SFMBT2,SEMA4G,CAMK2G,CH25H,NEURL1,LGI1,NMT2,FAM107B,ABI1,OPTN,PLEKHA1,WAC,CHST15,DPYSL4,TACC2,ADGRA1,NRG3,ZMYND11,POLL,PRLHR,ARHGAP19,HPSE2,USP54,SLC35G1,KCNMA1,HECTD2,FGFBP3,ZFYVE27,JAKMIP3,STK32C,BLOC1S2,CTNNA3,MXI1,SFR1,ANKRD16,WBP1L,HOGA1,CPEB3,WDR37,ZNF365,RUFY2,TET1,EPC1,SORCS3,ZCCHC24,ENKUR,STOX1,MMS19,SIRT1,TLL2,PDSS1,DNAJC12,ZNF32,MARCH8" Pubmed 12617826 Sexually dimorphic gene expression in the developing mouse gonad. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 11 26 "KDM5D,AMH,DDX3Y,MMD2,CBLN1,COL9A3,DTNA,PAK3,SERPINE2,SPP1,HHIP" Pubmed 23918385 Conditionals by inversion provide a universal method for the generation of conditional alleles. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 11 26 "CHRD,FLT1,MSTN,EXOSC10,RET,SOX2,SOX10,TEK,DICER1,SIRT1,TIE1" Pubmed 17698011 Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 11 26 "BMP7,HS3ST2,HMX1,IGFBPL1,SMAD1,SMAD9,SCN3B,CLSTN2,SST,TMEFF2,UCHL1" Pubmed 27789623 Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 11 26 "ASCL1,ELAVL3,ELAVL4,OLIG2,TUBB3,GAD1,NKX6-2,NKX2-2,SOX2,SOX10,SLC17A6" Pubmed 17614941 Novel genes differentially expressed in cortical regions during late neurogenesis. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 11 26 "NRP2,CDH8,TOX,DCT,PPP1R1B,TBR1,CSDC2,ZIC5,SCRT2,WSCD1,ATP13A2" Pubmed 15084498 bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "ASCL1,CALB2,EMX2,GFAP,HES5,NEUROD1,NEUROD2,PROX1" Pubmed 11157096 Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "AP2A1,AP2A2,DYNLL1,CLTA,CLTC,NTRK2,NTRK3,SH3GL2" Pubmed 27214567 Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "ASCL1,TUBB3,TBR1,KIF3A,PAX6,SLC1A3,SOX2,SATB2" Pubmed 12432077 Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "DOCK11,CDC42,DOCK4,DOCK2,DOCK7,DOCK10,DOCK9,DOCK8" Pubmed 19948250 Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "CALB1,CALB2,TBR1,GAD1,GFAP,NEUROD1,PAX6,SOX2" Pubmed 20463034 "Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "SPOP,OLIG2,GLI2,NKX2-2,PAX6,PTCH1,UBC,TMEM163" Pubmed 25530182 Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "SLIT2,DCC,OLIG2,TUBB3,NKX2-2,ROBO1,ROBO2,SLIT1" Pubmed 12771190 "SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "PDCD6IP,EGFR,PTK2B,GFAP,SH3KBP1,MASP1,PTK2,TUBA1A" Pubmed 25456121 A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "SLIT2,DCC,MAPT,ROBO1,ROBO2,SLIT1,ROBO3,CNTN2" Pubmed 29361054 Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "MYRF,OLIG2,MBP,PDGFRA,PLP1,SOX8,SOX2,SOX10" Pubmed 21945863 The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "TUBB3,NEFH,NTRK2,NTRK3,PRPH,ROBO3,CNTN2,CUX2" Pubmed 24781987 Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "CALB2,LHX2,TUBB3,TBR1,GFAP,DRAXIN,SOX2,SATB2" Pubmed 24376126 "Progressive effects of N-myc deficiency on proliferation, neurogenesis, and morphogenesis in the olfactory epithelium." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "LHX2,ELAVL3,ELAVL4,TUBB3,FOXG1,HES5,MYCN,NEUROD1" Pubmed 15634701 CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "ASCL1,CNTFR,DLX1,TUBB3,FGFR1,GAD2,IL6ST,LIFR" Pubmed 19936227 Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "CALB1,CALB2,ERBB2,TUBB3,MYO7A,NEUROD1,NTRK2,NTRK3" Pubmed 11156606 The transcription factor Sox10 is a key regulator of peripheral glial development. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "DCT,FABP7,TUBB3,HES5,KIT,MITF,PRPH,SOX10" Pubmed 16903783 Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "RALGAPA1,EPS15L1,CLTC,TOM1,ARFGAP2,AGFG1,EPN1,ITSN1" Pubmed 21664576 "Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "CDO1,BOC,CDON,OLIG2,GLI2,NKX2-2,PAX6,PTCH1" Pubmed 22632726 Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "SEMA6A,PLXNA4,SEMA3D,SEMA6C,NRCAM,SEMA6D,ZIC2,SEMA3B" Pubmed 14697242 "Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "ADGRB2,EPB41L1,TUBA1B,HMGCR,HSP90AA1,SMARCD3,KIF1B,TUBA1A" Pubmed 20392740 Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "BMPR1B,LHX2,ELAVL3,ELAVL4,TUBB3,FGFR1,FOXG1,HES5" Pubmed 12486001 "HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2A,TUBB1,TUBA1A" Pubmed 28434801 "Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord." Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "UNC5A,DCC,OLIG2,GLI2,RBPJ,SOX2,ROBO3,CNTN2" Pubmed 21147989 Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "HCN2,GAP43,MAP2,NCAM1,NCAM2,HCN1,PRPH,SLC17A6" Pubmed 24599474 The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. Pubmed 1.34E-05 1.00E+00 2.73E-03 3.52E-02 8 14 "ASCL1,OLIG2,TUBB3,GFAP,MBP,PDGFRA,MAPK3,SOX10" Pubmed 24097068 Discovery and refinement of loci associated with lipid levels. Pubmed 1.35E-05 1.00E+00 2.74E-03 3.54E-02 41 212 "BRAP,PLA2G6,AMPD3,GPAM,APOC1,GPR146,MTMR3,CAPN3,SCARB1,FADS2,CPS1,CSNK1G3,DLG4,TOM1,FAM13A,ABCA8,ERGIC3,HBS1L,STARD3,FRMD5,HMGCR,HPR,DOCK7,AFF1,PDE3A,A2ML1,PLEC,FTO,PLTP,PPARA,PXK,ASAP3,R3HDM2,RAB3GAP1,PHLDB1,EHBP1,TRPS1,VLDLR,EVI5,MARCH8,JMJD1C" Pubmed 22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Pubmed 1.36E-05 1.00E+00 2.75E-03 3.55E-02 23 91 "XKR4,PTCHD1,CDC42,DAPK1,TOMM20,SPOCK3,DYNC1I1,MAMLD1,IRAK4,TENM1,ATP8A1,CNTRL,KCND2,KCND3,TMEM110-MUSTN1,COL28A1,P2RY1,ZNF827,PDE4D,DCHS2,BCAS3,SGK1,LOC100129027" Pubmed 19367581 Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. Pubmed 1.51E-05 1.00E+00 3.05E-03 3.95E-02 18 62 "AMT,BSN,FEZ1,DRD1,ERBB4,CSPG5,GAD1,DISC1,GRM2,GRM3,HP,MAP4,CAMKV,PLXNB1,PPP3CC,PRODH,RGS4,SEMA3B" Pubmed 15163632 Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. Pubmed 1.51E-05 1.00E+00 3.06E-03 3.95E-02 16 51 "SERPINA3,MPDZ,CAMK2B,EN2,FABP7,OLFM1,SALL3,LMO1,MBNL1,MEF2C,PPP2R2B,ELOVL2,ROM1,RXRG,SOX11,WWC1" Pubmed 24332808 PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Pubmed 1.53E-05 1.00E+00 3.09E-03 4.00E-02 58 340 "RBM10,ADAR,ADD1,AP2A1,AP2A2,AP1B1,KCNAB2,CCAR2,BLM,CANX,CCNH,ARHGEF2,CLTC,NIPBL,SMARCAL1,RBM39,MATR3,INTS1,ELMSAN1,DDX46,EEF1A2,EGFR,POLR1B,SYNCRIP,SMC2,CELF1,TCERG1,ZNF638,NUDT21,TUBA1C,DIDO1,PSIP1,HNRNPK,MAP4,MOV10,HNRNPM,NUMA1,XRN1,EXOSC10,RPL15,RMI1,SFPQ,SMARCC2,LIMCH1,SPTAN1,RBM26,MPRIP,DNAJC9,COBL,WASHC4,TMPO,RBFOX2,TPM2,UBC,WRN,INTS3,RTN4,HNRNPA3" Pubmed 26633881 Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "UNC5A,DCC,DSCAM,EPHB1,NTNG2,NTNG1,UNC5B,UNC5D,RGMB,RGMA" Pubmed 20534675 Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "EBF1,GFRA1,GFRA2,NEFH,NTRK2,NTRK3,PRPH,RET,UCHL1,SLC17A7" Pubmed 16855091 Central roles of the roof plate in telencephalic development and holoprosencephaly. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "LHX2,EMX2,TUBB3,FOXG1,TBR1,SMAD1,SMAD9,PAX6,ZIC2,TMEM163" Pubmed 8464923 Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "APP,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIN1,PMP22,SPTAN1" Pubmed 21734270 Brn3a and Islet1 act epistatically to regulate the gene expression program of sensory differentiation. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "ETV1,TUBB3,FGF13,NTRK2,NTRK3,PIRT,PRPH,RET,SOX10,CNTN2" Pubmed 28684471 Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "ASCL1,FABP7,TUBB3,MITF,NOS1,PRPH,RET,S100B,SOX1,SOX10" Pubmed 21752992 Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "ASCL1,OLIG1,CDHR1,GAP43,GNAO1,STMN2,MEIS2,NCAM1,NEUROD1,SYP" Pubmed 20875817 DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Pubmed 1.54E-05 1.00E+00 3.09E-03 4.00E-02 10 22 "BMPR1B,CALB1,CALB2,DCC,TUBB3,GLUL,SMAD1,SMAD9,NEUROD1,PAX6" Pubmed 18557763 Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation. Pubmed 1.58E-05 1.00E+00 3.15E-03 4.07E-02 24 98 "ARNTL,ASCL1,CLOCK,ARNT2,OLIG1,HEYL,OLIG2,ATOH8,HES5,MITF,MXI1,MYCN,NEUROD1,NEUROD2,NHLH1,HES6,NPAS3,MESP1,TAL1,TCF4,TCF12,HIF3A,HEY1,HEY2" Pubmed 23459943 Common partner Smad-independent canonical bone morphogenetic protein signaling in the specification process of the anterior rhombic lip during cerebellum development. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "CALB1,TUBB3,TBR1,SMAD1,SMAD9,PAX6,POU3F2,CNTN2,ZIC1" Pubmed 12421703 The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "SEMA6A,CDH8,DLX1,EBF1,EFNA2,EMX2,EPHA5,FGFR3,GBX2" Pubmed 29343636 Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "ALCAM,SLIT2,CNTN1,DCC,MAPT,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 10567358 The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "AP2A1,AP2A2,EPS15L1,CLTA,CLTC,EGFR,EPN1,SH3GL2,EPN2" Pubmed 26511239 Retinoic Acid Receptor ? Controls Development of Striatonigral Projection Neurons through FGF-Dependent and Meis1-Dependent Mechanisms. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "ADORA2A,ASCL1,CHRM4,DRD1,GAD1,GAD2,PDYN,PENK,TAC1" Pubmed 20301612 Hirschsprung Disease Overview Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "ZEB2,EDN3,EDNRB,L1CAM,NF1,POLR2F,RET,SOX10,TCF4" Pubmed 22398208 Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "CALB1,CDH2,TUBB3,GFAP,GLUL,PAX6,CRB1,PARD3,CRB2" Pubmed 10640277 A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "ASCL1,DLX1,EMX2,TBR1,GAD1,STMN2,HES5,NEUROD1,PAX6" Pubmed 11955448 Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "OLIG1,OLIG2,GFAP,MBP,NKX2-2,PAX6,PDGFRA,PLP1,SOX10" Pubmed 19078961 Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2" Pubmed 26939553 Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "CELSR3,OLIG2,TBR1,GFAP,NFIA,PAX6,MAPK3,SATB2,FZD3" Pubmed 25113559 Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "ACHE,CALB1,CALB2,CELSR3,OLIG2,ETV1,GFAP,MAPT,SLC17A6" Pubmed 19806666 Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Pubmed 1.59E-05 1.00E+00 3.15E-03 4.07E-02 9 18 "OLIG2,TUBB3,TBR1,GAD1,MAP2,MBP,PAX6,PDGFRA,DICER1" Pubmed 20877624 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. Pubmed 1.63E-05 1.00E+00 3.23E-03 4.18E-02 129 926 "ABAT,ACADM,ACLY,AS3MT,METAP1D,SLC25A25,AK2,ABCD2,BBOX1,AMT,GPAM,ALDH4A1,ALDH7A1,BCS1L,DCAF5,BID,LDHD,NFS1,TBRG4,ZBED5,SLC25A27,LETMD1,COX4I1,CPS1,PNKD,CS,SNPH,EARS2,TOMM20,DBT,EXOG,SLC25A18,FIS1,TMTC1,AASS,ELN,COQ7,MRPL37,MRPL10,DNAJC27,ECSIT,TOMM40L,FECH,ATP5PD,COQ5,APOPT1,PRELID3A,PHYHIPL,GALC,MTHFD2,ACSS1,GATM,ALDH1L1,NFU1,GFER,DHRS4,GLDC,GLS,AIFM3,GPT2,GPD2,TDRKH,COQ10A,HMGCL,CPT1C,IDH3A,IDH3B,IBA57,SFXN5,PACRG,MOBP,MRPL42,MSRA,NDUFA5,ALDH1L2,NME4,NRDC,OGDH,OGG1,OPA1,PC,ETFRF1,DUSP26,SLC25A23,MTRF1L,SEPT4,POLG,TATDN3,CRLS1,FITM2,PRODH,NDUFS7,OCIAD1,ACSM5,QDPR,SLC25A48,OXR1,MRPS18A,SLC25A36,SUGCT,PRR5L,PTGR2,DGLUCY,SARS,HOGA1,SCP2,FOXRED1,SHMT2,NUBPL,MTERF2,EFHD1,SLC22A4,NAXD,OGDHL,KIF1B,ADHFE1,VAMP1,IQCE,TK2,PDSS1,AMACR,TST,BCL2L13,MTCH1,CCDC136,NT5M,PDSS2,MRPL47,PAK5" Pubmed 21102462 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Pubmed 1.65E-05 1.00E+00 3.27E-03 4.22E-02 15 46 "CCDC85A,BEGAIN,ARNTL,TMEM108,ARHGEF7,ECE2,LRP1B,PCSK2,PLCL1,FTO,PEX2,RXRG,TRA2B,CRTC1,CA10" Pubmed 20932939 Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Pubmed 1.68E-05 1.00E+00 3.32E-03 4.30E-02 45 243 "NR0B1,ATP1A1,FOXK1,CERS5,TOX,NR1D2,EN2,ETV1,TOMM40L,FHL1,FOXG1,FOXF2,FOXM1,NKX6-2,GBX2,TOX3,NR3C1,ZHX1,HMX1,HNF4G,IRF8,LIMS1,LMO1,MEIS2,NKX2-2,PAX6,PRRX1,POU3F2,POU3F4,POU6F1,PPARA,PROX1,ZFHX4,RXRA,RXRG,HES6,SOX6,LIMS2,SOX2,SOX10,ZHX3,TCF7L2,THRA,NR2E1,MEIS3" Pubmed 18978678 Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. Pubmed 1.70E-05 1.00E+00 3.36E-03 4.34E-02 21 80 "SLC12A5,SUGT1P4-STRA6LP-CCDC180,BMP7,CDH2,NRXN3,HS3ST5,ERBB2,FGFR1,FOXO3,FYN,GABRB3,GART,HSF2,PDGFRA,MTRF1L,PRRX1,PKN2,TGFBR3,TLR4,PDSS2,DPF3" Pubmed 25036637 A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. Pubmed 1.73E-05 1.00E+00 3.42E-03 4.42E-02 56 326 "ACTN1,GPRASP2,BIN1,AMT,DNAH17,ATP2A2,ATP2B1,COPB2,HECTD1,MAGED1,BAG4,SEC24C,VCAN,EDRF1,DNAJB6,EGFR,ERBB2,ERBB4,TUBA1B,TUBB4A,FER,GABRB1,USP19,NR3C1,MAEL,HSF2,HSPA1L,HSP90AA1,KLHL23,POC1B,HNRNPM,DNHD1,KSR2,PDCD2,PIK3R1,EPN1,SH3KBP1,PPP5C,PRPSAP2,CEP97,RADX,ROM1,MCMBP,FAM192A,COPZ1,HSPA4L,ITSN1,PHLDB1,SYNE2,DNAJC9,WBP2,HSPBP1,AMOT,XPO1,DHX33,TUBA1A" Pubmed 15745951 Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. Pubmed 1.74E-05 1.00E+00 3.42E-03 4.42E-02 13 36 "PKP4,MPDZ,DLX1,GABRG2,GBX2,HBA1,KCNC1,MARK1,FXYD7,ANLN,PHLDB1,RPRM,ZBTB16" Pubmed 23064961 GWAS of dental caries patterns in the permanent dentition. Pubmed 1.74E-05 1.00E+00 3.42E-03 4.42E-02 14 41 "PROM1,ABCG2,EDNRA,IL17D,CTNNA3,ZNF827,PCDH9,MYO16,SPP1,NFASC,AJAP1,PLPPR5,PHTF2,IFT88" Pubmed 28472653 Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "CX3CR1,OLIG2,GLUL,PAX6,PDGFRA,SOX2,SST" Pubmed 25209608 "Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype." Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "CALB1,CALB2,TBR1,GFAP,MEF2C,LINC00461,SATB2" Pubmed 27050589 Advancing the understanding of autism disease mechanisms through genetics. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "NRXN1,CNTNAP2,TBR1,NLGN3,SHANK2,TSC1,TSC2" Pubmed 21147077 Cellular expression of the K+-Cl- cotransporter KCC3 in the central nervous system of mouse. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "CALB1,CALB2,SLC12A6,GFAP,S100B,SLC1A3,SST" Pubmed 24338367 The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "ASCL1,SLC32A1,TUBB3,GAD1,GAD2,NCAM1,TNR" Pubmed 28970231 The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "GAD1,PRPH,ROBO1,ROBO2,ARX,SLIT1,ROBO3" Pubmed 10521398 Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "ACHE,ERBB2,GAP43,L1CAM,PRKAR1B,PTCH1,SOX10" Pubmed 29500351 Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "MYRF,OLIG2,MBP,NKX2-2,PDGFRA,PLP1,SOX10" Pubmed 15117958 90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "RTN3,FGFR1,PIK3R1,RTN1,SH3BP2,SLA,TNS2" Pubmed 26786414 Canonical Notch signaling plays an instructive role in auditory supporting cell development. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "EMX2,DKK3,RBPJ,SHC3,MYO7A,SOX2,DAAM2" Pubmed 11753414 Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "GAP43,SNAP25,STX1A,STXBP1,SYN1,SYP,SYT1" Pubmed 16380905 Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "DPYSL2,TUBA8,GRID1,GRM3,NOS1,RGS4,ATXN1" Pubmed 22500632 Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "NDRG2,MMD2,ARHGEF4,FGFBP3,NFIA,SLC1A3,ZCCHC24" Pubmed 18341993 Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "AP4M1,CACNG3,CACNG2,AP4B1,GRIA1,GRIA2,AP4E1" Pubmed 29920279 Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "APC,OLIG2,GFAP,MBP,PDGFRA,PLP1,SMARCA4" Pubmed 10409504 Role of Pax6 in development of the cerebellar system. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "DCC,TUBB3,MAPT,NCAM1,PAX6,ZIC1,ZIC2" Pubmed 10995443 Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "ACHE,ANK3,DMD,DTNA,DTNB,NOS1,SYP" Pubmed 19805384 C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "GUCY1B1,L1CAM,NPPA,NPR2,PRPH,CNTN2,SLC17A7" Pubmed 22627280 Olig2-dependent developmental fate switch of NG2 cells. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "OLIG2,ALDH1L1,GFAP,IFI16,MBP,PDGFRA,SOX10" Pubmed 12154121 Molecular mechanisms governing Pcdh-gamma gene expression: evidence for a multiple promoter and cis-alternative splicing model. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "PCDHGB4,PCDHGC5,PCDHGB6,PCDHGB2,PCDHGA11,PCDHAC2,PCDHA5" Pubmed 20648636 Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "APC,OLIG1,OLIG2,MBP,PDGFRA,PLP1,SOX10" Pubmed 21776083 Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "ASCL1,CALB2,TUBB3,GFAP,S100B,SNRPN,SOX2" Pubmed 21205893 TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "DRD1,PPP1R1B,NPY,NTRK2,DDR2,PENK,TAC1" Pubmed 25030704 Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "SLIT2,CNR1,L1CAM,MAPT,ROBO1,ROBO2,CNTN2" Pubmed 22789544 Innate neural stem cell heterogeneity determines the patterning of glioma formation in children. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "SLIT2,CNTN1,OLIG2,FABP7,CHL1,NF1,SOX2" Pubmed 17151198 Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "CA8,CALB1,EBF1,TUBB3,GFAP,SLC1A3,ZNF423" Pubmed 16481105 Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "GRIN3A,GRIN1,GRIN2C,GRIN2D,MAPK8,MAPK9,MAPK10" Pubmed 9924185 Review: Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,SST,TAC1" Pubmed 15064766 Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "SLC32A1,GAD1,STMN2,GRIA2,GRIK2,TLX1,SLC17A6" Pubmed 29192291 Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "ELAVL3,ELAVL4,TUBB3,NOS1,RET,SOX10,TACR1" Pubmed 11071752 Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "SOX8,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11" Pubmed 25652406 Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development. Pubmed 1.84E-05 1.00E+00 3.52E-03 4.55E-02 7 11 "CALB1,EDIL3,GFAP,GLI2,HMGCR,PTCH1,CNTN2" Pubmed 20392943 Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB1,CALB2,TUBB3,NOS1,RET,SOX10" Pubmed 18313668 Mice lacking the transcription factor Ikaros display behavioral alterations of an anti-depressive phenotype. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "DRD1,PPP1R1B,GAD1,GAD2,PENK,TAC1" Pubmed 26248544 Prospective separation and transcriptome analyses of cortical projection neurons and interneurons based on lineage tracing by Tbr2 (Eomes)-GFP/Dcx-mRFP reporters. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SOX1,SOX2,SOX5,CNTN2,SATB2,WNT7A" Pubmed 22982106 Distribution of protocadherin 9 protein in the developing mouse nervous system. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "PCDH10,CALB1,CALB2,NEFH,PCDH9,PRPH" Pubmed 22512338 Nectins localize Willin to cell-cell junctions. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "NECTIN3,AFDN,TJP1,PARD3,CADM1,FRMD6" Pubmed 12435606 N-terminal PDZ-binding domain in Kv1 potassium channels. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ACTN2,DLG4,KCNA1,KCNA2,KCNA4,KCND2" Pubmed 24931760 Cytoarchitecture of the olfactory bulb in the laggard mutant mouse. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB2,GFAP,MBP,NCAM1,RELN,S100B" Pubmed 27881777 Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "GPR37L1,ARHGEF4,GFAP,GLUL,SLC1A3,SPATA13" Pubmed 17729288 Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB2,GAD2,MEIS2,NOS1,SLC6A9,STX1A" Pubmed 9736654 TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "NTRK2,NTRK3,SNAP25,STX1A,SYP,SYT1" Pubmed 22298430 Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ARHGEF2,USP21,MAP4,MARK1,MARK3,UBC" Pubmed 20578039 Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "GFAP,GJB1,ITGAM,MBP,PLP1,GJC2" Pubmed 12826663 Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CADM3,NECTIN3,MPP6,AFDN,CADM1,CADM2" Pubmed 19640847 Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "DLGAP2,DLGAP1,DLGAP3,DLG4,SHANK1,GRIN1" Pubmed 27634570 Septin7 regulates inner ear formation at an early developmental stage. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SEPT7,EMX2,TUBB3,FOXG1,MYO6,SOX2" Pubmed 11239431 Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ASCL1,FABP7,GFAP,HES5,NEUROD1,RELN" Pubmed 18632947 Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "OLIG2,LINGO1,MAG,MBP,PLP1,RTN4" Pubmed 11517264 p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CDK5R1,CDK5R2,CALB1,CALB2,MAPT,NEFH" Pubmed 19515912 GPR56-regulated granule cell adhesion is essential for rostral cerebellar development. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB1,ADGRG1,FABP7,GFAP,SLC1A3,ZIC1" Pubmed 12798291 Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "GFAP,MAP2,NCAM1,NOS1,NTRK2,SOX2" Pubmed 18839409 Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "HS3ST2,NEFH,NTRK2,NTRK3,RET,UCHL1" Pubmed 25327963 Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "EGFR,EMX2,HES5,PAX6,S100B,SOX2" Pubmed 11698390 Tubulin seeds alpha-synuclein fibril formation. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "TUBA1B,TUBB3,MAPT,SNCB,SNCA,TUBA1A" Pubmed 23482493 CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CLIP3,TUBB3,PRPH,CLIP1,S100B,CLIP2" Pubmed 21382552 Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ASCL1,OLIG1,OLIG2,NKX2-2,PAX6,SOX10" Pubmed 12963086 Co-purification and localization of Munc18-1 (p67) and Cdk5 with neuronal cytoskeletal proteins. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "MAPT,NEFM,NEFH,STX1A,STXBP1,TUBB2A" Pubmed 16571605 Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB2,TUBB3,MAP2,NCAM1,RELN,ARX" Pubmed 9184108 Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "VCAN,NCAN,L1CAM,NCAM1,PTPRZ1,SYP" Pubmed 22216198 A genome-wide association study of the Protein C anticoagulant pathway. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "MYH7B,KCTD8,DNAJC6,ELMO1,LINGO1,FRMD6" Pubmed 19144833 The CREB/CREM transcription factors negatively regulate early synaptogenesis and spontaneous network activity. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CREM,GABRA1,GRIA2,GRIN1,L1CAM,CNTN2" Pubmed 24327345 Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "DBN1,DYRK1A,NEFH,SNAP25,SYN1,SYT1" Pubmed 23217150 "Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea." Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "BSN,SHANK1,GRIA1,GRIA2,GRIA4,PRPH" Pubmed 12966207 "Expression of FGF receptors 1, 2, 3 in the embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: implications for oligodendrocyte development." Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "OLIG1,OLIG2,FGFR1,FGFR3,PDGFRA,PLP1" Pubmed 25485759 PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "NRP2,SLIT2,ROBO1,ROBO2,SLIT1,SEMA3B" Pubmed 20549747 "Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus." Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "FABP7,GFAP,GLUL,S100B,SLC1A2,SLC1A3" Pubmed 16382103 International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "KCNT1,KCNMA1,KCNN1,KCNN2,KCNN3,KCNT2" Pubmed 10069332 "Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons." Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ACHE,GFRA1,GFRA2,RET,TAC1,UCHL1" Pubmed 11389829 Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SV2B,SV2A,KIF5A,SNAP25,KIF1B,SYP" Pubmed 11395011 Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SLC12A5,SLC12A6,GPHN,MAP2,SLC12A2,SLC12A4" Pubmed 16696976 Two mechanistically distinct forms of endocytosis in adrenal chromaffin cells: Differential effects of SH3 domains and amphiphysin antagonism. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "AP2A1,AMPH,DNM2,SH3GLB1,ITSN1,SH3GL2" Pubmed 18084280 Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "GPSM1,TUBB3,TBR1,PAX6,GPSM2,TJP1" Pubmed 7750641 Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CDH2,GAP43,L1CAM,MAP2,NCAM1,CNTN2" Pubmed 8565847 Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ASCL1,ENO2,GFAP,PRPH,RET,S100B" Pubmed 23884932 Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SLIT2,TUBB3,MYO6,ROBO1,ROBO2,SLIT1" Pubmed 28986144 Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SLIT2,DCC,TUBB3,ROBO1,ROBO2,SLIT1" Pubmed 22412988 Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "APC,ASCL1,L1CAM,MAP2,PAX6,CNTN2" Pubmed 17310244 Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "ARHGEF7,GIT2,DLG4,EPHB1,GIT1,SYP" Pubmed 22806432 Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "SLIT2,DCC,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 16387639 Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB2,DCLK1,TBR1,GFAP,DCLK2,L1CAM" Pubmed 23931996 Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues. Pubmed 1.93E-05 1.00E+00 3.55E-03 4.59E-02 6 8 "CALB2,CDH2,NECTIN3,TUBB3,AFDN,RELN" Pubmed 15778465 "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer." Pubmed 1.99E-05 1.00E+00 3.65E-03 4.72E-02 23 93 "APC,SYNJ2,MAGI1,TJP2,OSBPL3,SIPA1L1,ARHGAP32,HDAC4,DYRK1A,ZNF638,PARD3B,KLC1,MARK1,MARK3,PTOV1,MAPKAP1,MYCBP2,ST5,MPRIP,PARD3,KLC2,SPIRE1,GAN" Pubmed 18022353 New nomenclature for chromatin-modifying enzymes. Pubmed 1.99E-05 1.00E+00 3.66E-03 4.73E-02 16 52 "KDM5D,NCOA1,KMT2C,CLOCK,KMT5B,KAT8,DOT1L,KDM2B,KAT7,KDM4D,KDM4B,KDM3A,KDM4C,NSD1,PRDM2,KAT6A" Pubmed 22020285 Image-based genome-wide siRNA screen identifies selective autophagy factors. Pubmed 2.05E-05 1.00E+00 3.76E-03 4.86E-02 33 159 "ADRB2,MYOM1,C5,KIAA1549L,HAPLN1,FAM131B,BOC,TBC1D5,RIMS3,PHYHIP,IST1,REEP2,CLVS1,FGF14,ZCCHC17,CSPG5,GABRA5,MSTN,HPR,KCNK3,NEFM,SNTG1,PFKP,STK32A,SLC1A3,SLC6A1,SLCO1A2,MBD5,TNIK,NR2C2,ZNF189,MAP3K12,DPF3" Pubmed 20801516 Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip. Pubmed 2.05E-05 1.00E+00 3.77E-03 4.87E-02 22 87 "BBS2,CA4,CNGA3,USH1C,OPTN,ADGRV1,EFEMP1,MITF,MYO7A,NDP,PAX6,RGR,RLBP1,ROM1,RPE65,RIMS1,ELOVL4,SEMA4A,CRB1,TTPA,BEST1,PCDH15" Pubmed 24431450 Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum. Pubmed 2.06E-05 1.00E+00 3.77E-03 4.88E-02 11 27 "CALB1,FABP7,TUBB3,GFAP,NEUROD1,PAX6,PDGFRA,MAPK3,SLC1A3,SOX2,CNTN2" Pubmed 15203218 Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Pubmed 2.09E-05 1.00E+00 3.82E-03 4.94E-02 21 81 "SNX32,DCLK1,CSF1R,CNTNAP2,SGK2,ADGRV1,TUBB3,DIDO1,KCNK2,ADAM11,MYBPC1,MYH3,SDK2,PTPA,BSDC1,URGCP,ZNF423,TPCN2,CSMD1,WNK1,ADAMTS10" Pubmed 22139419 New gene functions in megakaryopoiesis and platelet formation. Pubmed 2.09E-05 1.00E+00 3.82E-03 4.94E-02 21 81 "TAOK1,KALRN,SIRPA,TMCC2,ANKMY1,HBS1L,MEF2C,PLEC,PSMD13,SATB1,COPZ1,RPH3A,KIF1B,SYN2,ZFPM2,CBX5,TPM1,TPM4,TUBB1,DOCK8,JMJD1C" Pubmed 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 2.17E-05 1.00E+00 3.98E-03 5.14E-02 63 383 "APC,ARRB1,ARRB2,CHRD,NCOA1,RIPK1,BMP7,BMPR1B,NOG,CNTFR,CRHBP,CSF1,CSF1R,CSF3R,DLX1,EGFR,EGR3,FGF1,FGFR1,FGFR3,FLT1,DLL3,DKK3,MSTN,GHR,PPARGC1A,GLI2,MCHR1,NR3C1,WIF1,IRAK3,HSD17B1,IGF1,IGFBP1,IL6R,IL6ST,LIFR,SMAD1,MEF2C,NTRK2,NTRK3,P2RX7,PPARA,MAPK3,PTCH1,PTHLH,PTH1R,PTN,RXRA,RXRG,SOX6,SOX5,SPP1,TCF4,TCF7,TGFBR3,THRA,HEY1,TLR4,TNFRSF1B,PIK3R5,TRH,WNT7A" Pubmed 19454010 In vitro nuclear interactome of the HIV-1 Tat protein. Pubmed 2.30E-05 1.00E+00 4.20E-03 5.42E-02 38 195 "ARID1A,ADAR,MTA3,EP400,DYNLL1,CCNT1,AHCTF1,RBM39,MATR3,MYEF2,HP1BP3,DDX46,EEF1D,ERCC2,TUBB3,RACK1,NOP56,SMC2,STAU2,ZNF512,ZNF638,KAT7,DDX19B,HNRNPM,NUMA1,RBBP6,DPF2,PBRM1,DHX30,SMARCA4,SMARCC2,TMPO,ZNF384,TUBB2A,UBTF,MEAF6,NSD2,XPO1" Pubmed 12040188 A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Pubmed 2.30E-05 1.00E+00 4.20E-03 5.42E-02 28 126 "ZMYM4,RUBCN,DLG2,GRIN3A,DENND4A,MRVI1,DLC1,KIAA1109,NBEA,MPP6,GOLGB1,CNTRL,SERP2,IBA57,ERICH3,C10orf105,CCDC13,NUDT11,STUM,KIF16B,ANKFN1,UNC80,ENHO,ERCC6L2,CLEC2L,CCDC136,ADAMTS9,NAV2" Pubmed 24623722 Systematic identification of pathological lamin A interactors. Pubmed 2.32E-05 1.00E+00 4.24E-03 5.48E-02 57 337 "OSBPL8,C1QTNF1,ASGR1,BCL2L2,C5,MMD2,CACNG1,SYT6,CLDN10,USP2,CD81,IFFO1,CRY2,CMTM5,MYADM,CNIH3,GOLT1B,TMEM74,RTN3,FDFT1,SCARA3,VTI1B,TMEM107,PRELID3A,MTHFD2,STARD3,SERP2,GRM2,ACOT7,ZDHHC15,ITGAM,KCNK1,SMAD1,FXYD6,NINJ2,SMIM11A,NALCN,PLP1,PMP22,FA2H,CYBC1,RTN1,SLC2A5,LIMS2,SLN,DBNDD2,STAC2,VAMP1,SYPL1,TMPO,RPRM,SLC35A4,SLC13A3,PLPP4,ZNF138,SLC30A3,RTN4" Pubmed 19286674 Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Pubmed 2.35E-05 1.00E+00 4.29E-03 5.54E-02 12 32 "OLIG2,TUBB3,GLI2,KIF3A,HES5,NKX2-2,PAX6,POU3F2,PTCH1,DBX2,SOX1,IFT88" Pubmed 23444366 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. Pubmed 2.37E-05 1.00E+00 4.33E-03 5.59E-02 14 42 "HECTD1,HDAC4,CEP170,WDR20,SPEG,AFDN,CDK18,PDE3A,MYCBP2,EPB41L3,TPD52,TPD52L2,WNK1,MFF" Pubmed 25201988 Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Pubmed 2.39E-05 1.00E+00 4.35E-03 5.62E-02 23 94 "PITPNM2,ZFAT,PPFIA2,NRXN1,SH2B1,CEP170,TBR1,IP6K3,GART,GPM6A,ATXN2L,NEGR1,KCNMA1,MDM4,POU3F2,SEMA6D,LINC00461,ITSN1,SNAP25,MAPKBP1,LRRC24,CELF4,JMJD1C" Pubmed 16783635 Quantitative trait loci for body size components in mice. Pubmed 2.39E-05 1.00E+00 4.35E-03 5.62E-02 23 94 "FZD9,DDR1,FBXO7,FGFR1OP2,ADGRV1,FGF12,NRG3,ZNF546,IGF1,PTHLH,PTH1R,PTX3,ZSCAN2,RASGRF2,RFX4,KIF7,PBRM1,SOX5,APOM,FGD4,TAF6,WNT7A,ST8SIA2" Pubmed 28288114 Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Pubmed 2.49E-05 1.00E+00 4.51E-03 5.83E-02 10 23 "DLGAP3,ETV1,GATM,NPY,PAX6,PDYN,PMP22,ATXN1,SATB2,CUX2" Pubmed 15163631 Presenilin 1 in migration and morphogenesis in the central nervous system. Pubmed 2.49E-05 1.00E+00 4.51E-03 5.83E-02 10 23 "TUBB3,TBR1,GAD1,GBX2,HES5,NEUROD1,PAX6,PROX1,RELN,CNTN2" Pubmed 20301690 Brugada Syndrome Pubmed 2.49E-05 1.00E+00 4.51E-03 5.83E-02 10 23 "CACNA2D1,CACNB2,ABCC9,FGF12,KCND2,KCND3,KCNH2,SCN2B,SCN3B,KCNE5" Pubmed 19149881 Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Pubmed 2.49E-05 1.00E+00 4.51E-03 5.83E-02 10 23 "AXIN2,APC,ASCL1,CDH2,OLIG2,TUBB3,FOXG1,TBR1,PAX6,PTCH1" Pubmed 15890332 Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells. Pubmed 2.49E-05 1.00E+00 4.51E-03 5.83E-02 10 23 "TTYH1,CD81,CHGB,EDNRB,FABP7,NSG2,NSG1,IGFBPL1,PTPRZ1,SEPT8" Pubmed 16778019 Characterization of the piRNA complex from rat testes. Pubmed 2.52E-05 1.00E+00 4.57E-03 5.90E-02 27 120 "USP31,ARHGAP20,CDK10,ZBTB10,USP2,SEC31B,IP6K1,SLC43A2,DNAJC27,FKTN,ANKFY1,ARFGAP2,SPIN1,DDX19B,SMIM7,PRKAB2,RAD51D,ZYG11B,KDM3A,MLC1,ZC3H4,TACC1,RPGRIP1L,CBX5,NR2C2,STXBP4,TUB" Pubmed 27542412 Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development. Pubmed 2.57E-05 1.00E+00 4.66E-03 6.02E-02 20 76 "TNRC6C,PDXK,CSNK1E,SACS,SEC23B,FLNC,GFAP,GOLGB1,TUBA1C,TUBB2B,PDE4D,PLEC,MAPK3,USP47,SON,MYCBP2,PRRC2C,TCF12,TUBB2A,TUBA1A" Pubmed 20686565 "Biological, clinical and population relevance of 95 loci for blood lipids." Pubmed 2.59E-05 1.00E+00 4.66E-03 6.03E-02 31 147 "BRAP,PLA2G6,AMPD3,GPAM,APOC1,APOC2,CAPN3,SCARB1,FADS2,NCAN,TOMM20,ABCA8,ERGIC3,STARD3,PSRC1,FRMD5,HMGCR,HP,HPR,DOCK7,AFF1,PDE3A,PLEC,PLTP,R3HDM2,CCDC92,RAB3GAP1,ZHX3,TRPS1,EVI5,JMJD1C" Pubmed 10381338 Quantitative analysis of expression of mouse sialyltransferase genes by competitive PCR. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ST3GAL5,ST8SIA3,ST6GALNAC3,ST8SIA5,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" Pubmed 19884655 Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ELAVL3,ELAVL4,FABP7,TUBB3,GFAP,MAPK3,SOX10,SYP" Pubmed 27213272 The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "APC,OLIG1,OLIG2,GFAP,MAG,MBP,NKX2-2,PDGFRA" Pubmed 18165280 "COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "EMX2,ETV1,TUBB3,FGFR3,TBR1,PAX6,MAPK3,FEZF2" Pubmed 29911975 Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "PTK2B,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 18255031 Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ETV1,TBR1,L1CAM,POU3F2,FEZF2,RORB,SATB2,CUX2" Pubmed 10932191 "A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "HEPH,KIT,KITLG,AFF1,PMP22,FBXO11,SNAP25,ZIC2" Pubmed 14976552 "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "TAOK1,MARK4,BRSK2,STRADA,BRSK1,CAB39,MARK1,SIK3" Pubmed 27935475 Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "SLC12A5,CDH8,TBR1,GBX2,RORB,SST,SLC17A7,SLC17A6" Pubmed 29507213 Liver X receptor ? regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "CALB1,CALB2,DLG4,FABP7,GFAP,PROX1,SOX2,SYP" Pubmed 26818521 MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "TUBB2B,MYO6,MYO7A,MAPK8,PROX1,SOX2,TUBB2A,TUBB1" Pubmed 24453333 Differential neuronal targeting of a new and two known calcium channel ?4 subunit splice variants correlates with their regulation of gene expression. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNA2D2" Pubmed 20431123 Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "CALB2,TUBB3,TBR1,HES5,PAX6,RELN,FEZF2,RORB" Pubmed 23782696 "Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "LRRC7,ARRB2,ADGRB1,MAGI1,MAGI2,DLG4,MAGI3,PDZD2" Pubmed 12571103 Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ACHE,ASCL1,DLX1,ETV1,PPP1R1B,MEIS2,PAX6,NR2E1" Pubmed 16007083 "Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "CALB1,CALB2,DLX1,GAD1,NOS1,NPY,RELN,SST" Pubmed 22071110 Six3 is required for ependymal cell maturation. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ASCL1,NOG,OLIG2,FABP7,TUBB3,GFAP,S100B,SLC1A3" Pubmed 10934256 Origin and molecular specification of striatal interneurons. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ASCL1,CALB1,CALB2,PPP1R1B,NOS1,NPY,PENK,SST" Pubmed 21745462 Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "PRX,SPTBN4,CDH2,CNTN1,CNTNAP2,DRP2,NRCAM,PTPRZ1" Pubmed 17356169 Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "PLXNA4,ARNT2,DLX1,PLXNC1,TUBB3,NPTX1,NPTX2,PLXNB1" Pubmed 24623842 GABRA1 and STXBP1: novel genetic causes of Dravet syndrome. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "RIMS2,GABRA1,KDM2B,CLSTN1,SLC8A1,KIF1B,STXBP1,SPATA13" Pubmed 15976074 Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ASCL1,EBF1,DLL3,HES5,MAP2,NKX2-2,PDGFRA,RET" Pubmed 19320733 Pigmentation-related genes and their implication in malignant melanoma susceptibility. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "EDNRB,VPS13B,KIT,MITF,MYO5A,MYO7A,SOX10,MGRN1" Pubmed 10679268 "Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains." Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "SH2B1,CSF1R,PTK2B,JAK2,KIT,MATK,PIK3R1,VAV1" Pubmed 20188150 Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNA2D2" Pubmed 16957084 Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3. Pubmed 2.63E-05 1.00E+00 4.66E-03 6.03E-02 8 15 "ASCL1,CALB1,CALB2,LHX2,TUBB3,FOXG1,PAX6,RELN" Pubmed 24613305 Proximity interactions among centrosome components identify regulators of centriole duplication. Pubmed 2.70E-05 1.00E+00 4.78E-03 6.18E-02 24 101 "CDC7,MAGED1,SIPA1L1,PUM1,KIAA0586,SPATA2,KIAA0753,MAP7D2,DOCK7,USP54,KIF2A,MARK3,MYO9A,A2ML1,CEP97,KIF7,CDK5RAP2,TNIK,MYCBP2,PJA1,FBXW11,CLASP1,CCDC14,GOPC" Pubmed 15363391 Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "CALB1,CALB2,GLUL,NEUROD1,PAX6,PROX1,SLC6A1,SLC6A9,STX1A" Pubmed 21471366 Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "APC,CALB1,CALB2,DLX1,ETV1,TBR1,MEF2C,NOS1,PAX6" Pubmed 24465223 FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "EMX2,FGFR1,FOXG1,HES5,MYO7A,MAPK3,PROX1,SOX2,HEY2" Pubmed 28031177 DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "AXIN2,NRP2,CDH8,LHX2,EMX2,GRIK4,PAX6,PROX1,RORB" Pubmed 29285798 Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "OLIG2,GFAP,MBP,NFIA,NKX2-2,PAX6,RELN,S100B,SOX2" Pubmed 16026391 Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "CALB1,CALB2,GAD1,GAD2,GLUL,NOS1,PAX6,SLC6A9,STX1A" Pubmed 15051154 Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "SEMA6A,SEMA7A,SEMA4G,NRP2,SEMA6C,SEMA4D,SEMA5B,SEMA4A,SEMA3B" Pubmed 17461779 Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "CLTC,CPS1,TUBA1B,DHRS4,MAPKAP1,PRR5L,MLST8,RICTOR,TUBA1A" Pubmed 16306355 The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "SOX21,NKX2-2,SOX8,SOX2,SOX5,SOX10,SOX11,SOX15,SST" Pubmed 23903190 GDNF is required for neural colonization of the pancreas. Pubmed 2.76E-05 1.00E+00 4.85E-03 6.27E-02 9 19 "ELAVL3,ELAVL4,TUBB3,GFAP,GFRA1,GFRA2,NKX2-2,RET,SOX10" Pubmed 16754659 Stable association between G alpha(q) and phospholipase C beta 1 in living cells. Pubmed 2.87E-05 1.00E+00 5.03E-03 6.50E-02 23 95 "ADRA1D,ADRA1B,AGT,CCK,CCKBR,CHRM1,EDN1,EDN3,EDNRA,EDNRB,LPAR6,GPR17,LPAR4,MCHR1,HTR2A,OXTR,PTAFR,PLCB1,TAC1,TAC3,TACR1,TRH,NTSR2" Pubmed 23443559 LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Pubmed 2.88E-05 1.00E+00 5.04E-03 6.52E-02 94 639 "SDE2,ABR,LRCH2,PPFIA1,APC,PPFIA3,CASK,CAMK2D,ARHGEF2,CDC27,MYL6B,HECTD1,MAGED1,TCEAL2,ZNF385A,AKAP12,NCOR2,UBXN2A,CTNND1,PUM1,PPP6R2,TCAF1,DCAF8,MATR3,HP1BP3,CEP170,SEC16A,EEF1A2,FRY,ACSL4,TUBA1B,TUBB3,TUBB4A,CEP78,FECH,FGFR1,NEURL4,SEPT9,TUBGCP4,TCERG1,TNRC6A,PCLO,TUBA1C,PARD3B,GRIN2D,PSIP1,HBA1,HPCA,HSPA1L,HSP90AA1,IDH3B,DOCK7,TUBB2B,LAMP2,MOV10,HNRNPM,NAP1L1,PCMT1,PIK3C2A,STRN3,PACSIN1,PPM1B,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PSMA6,CEP97,PBRM1,RPRD1A,ARMC5,RPL15,RPL38,RPS20,SBF1,PUF60,CCDC88A,SMARCE1,ZSWIM8,UNC5B,SPTAN1,NSFL1C,PRRC2C,OBSL1,DICER1,TPD52L2,TUBB2A,TUBB1,EIF4ENIF1,AMOT,KLC2,TUBA1A,SLC4A10,LAS1L" Pubmed 26238476 Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Pubmed 2.91E-05 1.00E+00 5.09E-03 6.58E-02 38 197 "SPARCL1,PTCH2,BMPR1B,JAZF1,CNTFR,WHRN,IGDCC3,CREB5,NCOR2,EDNRB,TMTC1,FOXF2,EFCAB2,SALL3,DIPK1C,KIT,FGFBP3,MEIS2,CLDN11,PBX1,SDK2,PTPA,RASGEF1B,SLC26A11,PTCH1,PLPPR1,SALL1,CXXC4,CLSTN2,SMOC1,POPDC3,HHIP,SMUG1,FAM181B,PLPPR2,ZIC3,LYPD6,PMEPA1" Pubmed 27210758 Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Pubmed 2.93E-05 1.00E+00 5.13E-03 6.62E-02 15 48 "CALB1,CALB2,OLIG2,ETV1,KCND2,NKX2-2,PAX6,KCNIP3,SALL1,SATB1,SOX2,SPP1,SATB2,ZFPM2,ZBTB16" Pubmed 14743216 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Pubmed 3.05E-05 1.00E+00 5.34E-03 6.90E-02 33 162 "CCAR2,RIPK1,BCL7A,BTRC,CALM1,SPAG9,USP2,COPB2,CLTC,CS,PPP6R2,SEC16A,POLR1B,IQGAP2,HSPA1L,HSP90AA1,KTN1,PDCD2,PSMA6,PSMD13,ANKHD1,ATG16L1,DPF2,FBXW7,SMARCA4,SMARCC2,SMARCE1,TAB2,ANKRD28,FBXW11,TNFRSF1B,TPM3,NR2C2" Pubmed 28560839 Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Pubmed 3.09E-05 1.00E+00 5.40E-03 6.97E-02 11 28 "CALB1,FABP7,TUBB3,GFAP,GLI2,SOX21,PAX6,PROX1,PTCH1,SOX1,SOX2" Pubmed 19762422 Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins. Pubmed 3.09E-05 1.00E+00 5.40E-03 6.97E-02 11 28 "GPC2,COL9A1,FGFR1,FGFR3,FOXG1,SMAD1,SMAD9,MAPK3,PTCH1,SPP1,VANGL2" Pubmed 18839057 Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. Pubmed 3.09E-05 1.00E+00 5.40E-03 6.97E-02 11 28 "CSMD2,KALRN,CREB5,DNM1,AK8,MAN2A2,MOBP,MYT1L,UNC5B,ASTN2,TLL2" Pubmed 12435358 Noggin is required for correct guidance of dorsal root ganglion axons. Pubmed 3.09E-05 1.00E+00 5.40E-03 6.97E-02 11 28 "SEMA6A,SEMA7A,SEMA4G,ASCL1,NOG,EFNB3,SEMA6C,SEMA4D,SEMA5B,SEMA4A,SEMA3B" Pubmed 15449545 Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Pubmed 3.11E-05 1.00E+00 5.42E-03 7.00E-02 21 83 "INTS2,CARMIL3,ARHGEF1,ZNF521,BOC,GGT7,CNTRL,ARHGAP19,TMEM104,ANKHD1,USP47,ATG16L1,ARMC5,PEAR1,GALNT10,FAM102A,ARHGEF40,IFT122,MVB12B,DOCK8,LAS1L" Pubmed 19077034 Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Pubmed 3.21E-05 1.00E+00 5.59E-03 7.22E-02 14 43 "TBC1D14,USP6,EVI5L,USP6NL,TBC1D5,SGSM2,RABGAP1L,TBC1D16,TBC1D25,RAB3A,SGSM1,RAB3GAP1,TBC1D15,EVI5" Pubmed 24705354 The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. Pubmed 3.34E-05 1.00E+00 5.81E-03 7.51E-02 41 220 "ADD1,SEMA4G,STX16,CBS,PLEKHB1,SUMF2,FEZ2,EDRF1,KIAA0408,TOX,WDR20,RAB39B,FAM135B,TMTC1,OPTN,WAC,PRMT5,BAIAP2,EVL,ZCCHC17,FUT9,MYOZ2,AHDC1,GPM6A,GRB10,ZNF667-AS1,ODF2,PDE4D,PDPK1,PIK3R1,PPP2R5E,BCAS3,QRICH1,TTLL7,PBRM1,ASIC4,ZFP2,SLC1A3,TMCC1,SP2,LMAN2L" Pubmed 26002199 The Repeat Expansion Diseases: The dark side of DNA repair. Pubmed 3.37E-05 1.00E+00 5.86E-03 7.57E-02 12 33 "CACNA1A,DMPK,ATN1,AFF2,NOP56,ZNF713,PPP2R2B,ATXN1,ATXN2,ATXN7,TCF4,JPH3" Pubmed 16870172 Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Pubmed 3.37E-05 1.00E+00 5.86E-03 7.57E-02 12 33 "CDO1,SLIT2,EYA1,BAIAP2,SYNCRIP,DKK3,BRD8,NPPA,IRX1,CXXC4,VSNL1,TMEM163" Pubmed 26657772 The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Pubmed 3.38E-05 1.00E+00 5.87E-03 7.58E-02 13 38 "CALB1,CDH2,OLIG2,FABP7,TUBB3,GFAP,PAX6,PDGFRA,RELN,S100B,HEY1,TJP1,PARD3" Pubmed 9039502 Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. Pubmed 3.77E-05 1.00E+00 6.54E-03 8.45E-02 21 84 "KDM5D,BCL2L2,WASF1,RUBCN,TM9SF4,TBC1D5,RIMS3,PHYHIP,SPOCK2,IP6K1,SMG7,DOCK2,GRB10,PALM,MYO18A,SEPT8,FAM168A,ARC,PUM2,TSC1,ZNF142" Pubmed 24721909 Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Pubmed 3.84E-05 1.00E+00 6.66E-03 8.61E-02 15 49 "LRIG1,TM9SF4,DLG4,USH1C,MAD2L2,MYO5A,MYO6,MYO7A,DUSP26,PPP3CA,CYBC1,OXR1,WDR37,RPGRIP1L,HIRA" Pubmed 23892456 A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal. Pubmed 3.85E-05 1.00E+00 6.66E-03 8.61E-02 30 143 "ARID1A,MTA3,NR0B1,EP400,KMT2C,NCOR1,PUM1,INTS1,ELMSAN1,MYEF2,SEC16A,KAT8,RGPD5,SALL3,BRD8,MOV10,RCOR2,DPF2,SALL1,TET1,SOX2,POGZ,TAF9,TBL1X,PUM2,RBFOX2,HIRA,UBTF,ZIC3,EMSY" Pubmed 19369396 A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "HES5,MEIS2,PBX1,PTCH1,HES6,SOX2,SOX3,SOX5,SOX11,WNT7A" Pubmed 19110265 "Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia." Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "INA,CRYM,DNM1,DPYSL2,ATP5PD,GFAP,HSP90AA1,MBP,PCMT1,TF" Pubmed 24335253 Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "ASCL1,CALB1,GAD2,GBX2,GFAP,MEIS2,PAX6,SOX2,ZIC1,SLC17A6" Pubmed 24023788 Gene network analysis in a pediatric cohort identifies novel lung function genes. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "FOXK1,CDH2,CTIF,MED12L,CTNNA3,MYBPC1,IGSF11,GSTCD,MYO16,PSD3" Pubmed 27578785 The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "ASCL1,DLX1,OLIG2,GAD1,GFAP,NR3C1,NPY,SOX2,SST,TRH" Pubmed 25240745 A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "CDH18,ZNF521,CHD1L,EDIL3,MRPL37,SH3YL1,CAP2,ST6GALNAC3,SLC8A1,NPAS3" Pubmed 19208226 Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "SLC12A5,BOC,EBF1,CELSR3,TMEM35A,KCNA1,LMO1,RGS4,TNS1,TUB" Pubmed 11493561 Emx2 directs the development of diencephalon in cooperation with Otx2. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "DLX1,EBF1,EFNA2,EMX2,EN2,FOXG1,GAP43,GBX2,PAX6,TCF7L2" Pubmed 19088086 Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. Pubmed 3.90E-05 1.00E+00 6.71E-03 8.67E-02 10 24 "ASCL1,ELAVL3,ELAVL4,OLIG2,GAD1,GAD2,NKX2-2,PAX6,SOX2,SLC17A6" Pubmed 20453000 A Large-scale genetic association study of esophageal adenocarcinoma risk. Pubmed 3.94E-05 1.00E+00 6.78E-03 8.76E-02 58 351 "AXIN2,APAF1,APC,GPAM,ALDH4A1,ATM,BARD1,RGS11,BID,CFLAR,CBS,ABCG2,CHD1L,HAPLN1,RGS6,CX3CR1,EGFR,RGS17,ERBB2,ERCC2,FLT1,MTHFD2,ALDH1L1,GHR,PPARGC1A,DIDO1,GRIK1,HSD17B1,IGF1,IGFBP1,IL6R,IL12A,ITGA7,LIG4,MTR,NPY,OGG1,PDGFRA,ABCB1,PIK3C2A,PMS2,PTPN13,RAD52,RET,REV3L,IL17RB,SPP1,SSTR1,SSTR2,ABCC8,TP53BP1,CHST5,TSC1,TSC2,WRN,XRCC4,ZNF24,EMSY" Pubmed 17646384 Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CDK5R1,CALB1,TUBB3,GFAP,MAP2,MAPK3,RELN" Pubmed 22017987 Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "FABP7,TUBB3,TBR1,GFAP,MAP2,PAX6,SATB2" Pubmed 22820053 The onion skin-like organization of the septum arises from multiple embryonic origins to form multiple adult neuronal fates. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CALB1,CALB2,OLIG2,NOS1,PAX6,SOX6,ZIC1" Pubmed 16162939 Absence of Fyn and Src causes a reeler-like phenotype. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CALB1,CALB2,TUBB3,TBR1,FYN,RELN,PTK2" Pubmed 25050931 Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ASCL1,CALB1,TUBB3,TBR1,GFAP,HES5,PAX6" Pubmed 19095005 New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ATP2A2,JPH4,TMEM38A,RYR1,RYR3,SLC8A1,JPH3" Pubmed 20159447 Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CALB2,FOXG1,TBR1,NKX6-2,NPY,PTCH1,SST" Pubmed 24559674 Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CNTN1,CHL1,L1CAM,NCAM1,NRCAM,CNTN3,CNTN2" Pubmed 22645310 Prolyl isomerase Pin1 regulates neuronal differentiation via ?-catenin. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "DLG4,FABP7,TUBB3,GFAP,PAX6,RELN,RBBP8" Pubmed 23217742 Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ISPD,SLIT2,EDIL3,L1CAM,ROBO1,ROBO2,SLIT1" Pubmed 20639873 Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CALB1,CALB2,OLIG1,OLIG2,TUBB3,TBR1,SST" Pubmed 16120638 Notch signaling coordinates the patterning of striatal compartments. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ASCL1,EBF1,PPP1R1B,FOXG1,GRIA1,HES5,NEUROD1" Pubmed 8288240 Molecular diversity of the SCG10/stathmin gene family in the mouse. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CCK,FGR,STMN2,STMN1,NPPA,LAMA1,VAV1" Pubmed 22678282 Cis-regulatory control of corticospinal system development and evolution. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "L1CAM,PRKCG,RELN,FEZF2,SOX5,SOX11,ZFPM2" Pubmed 18796539 alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "SPTBN4,EPB41,EPB41L2,TUBB3,MYO7A,SPTAN1,SPTB" Pubmed 16766700 A role for proneural genes in the maturation of cortical progenitor cells. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ASCL1,DLX1,TUBB3,NEUROD1,PAX6,UNC5D,CUX2" Pubmed 20419449 "Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people." Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "ADCY5,MADD,CRY2,DGKB,IGF1,PROX1,AGMO" Pubmed 17553984 Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "CALB1,CDH2,NCAM1,NEUROD1,NFIA,NFIX,S100B" Pubmed 14687546 Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "NUMB,CDH2,NUMBL,ETV1,TUBB3,HES5,RELN" Pubmed 19782674 Robo2 is required for Slit-mediated intraretinal axon guidance. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "SLIT2,TUBB3,PAX6,ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 20397748 Genome-wide association study of height and body mass index in Australian twin families. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "LCORL,EFEMP1,LAMA2,FTO,SH3GL3,HHIP,ADAMTSL3" Pubmed 21452241 Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala. Pubmed 4.04E-05 1.00E+00 6.83E-03 8.83E-02 7 12 "TIAM2,DLX1,PPP1R1B,GAD1,GNAL,RXRG,TAC1" Pubmed 23455922 Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Pubmed 4.09E-05 1.00E+00 6.92E-03 8.94E-02 70 447 "AXIN2,TAOK1,ZNF687,DYNLL1,ATP1A1,ATP2A2,BACH1,DST,ARHGEF7,BTRC,CCNT1,AIFM1,CDK11B,CDC42,HECTD1,ARHGEF6,AKAP7,AKAP5,MAGED1,PNKD,CSNK1E,PDE4DIP,FGFR1OP2,RASSF2,HP1BP3,SEC16A,DYRK1A,YAF2,VPS13B,SRRM1,PRMT5,PRKAG2,SEC23B,C2orf88,AHCYL1,RNPS1,HSP90AA1,LIMS1,AFF1,MOV10,GIT1,ADAM22,CDK18,PFKP,PKM,STRN3,PRKAB2,PRKACB,PRKAR1B,PRKCB,SNX22,RPS6KA2,ZNF568,DHX30,LIMS2,CDK5RAP2,ZSWIM8,ERC1,CLASP2,EPB41L3,STAU1,PRRC2C,MMS19,FBXW11,OBSL1,TNS2,AHCYL2,DICER1,GPR161,STOX2" Pubmed 11252894 Three ways to make a vesicle. Pubmed 4.29E-05 1.00E+00 7.21E-03 9.32E-02 14 44 "AP1B1,ARRB1,AP1M1,CLTA,CLTC,SEC24C,PUM1,DNAJC6,BLOC1S6,DNM2,SEC24B,VTI1B,SH3GL2,SEC31A" Pubmed 19877281 Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion. Pubmed 4.29E-05 1.00E+00 7.21E-03 9.32E-02 14 44 "NRP2,DCC,RASA4,CEND1,EYA1,NRN1,CHL1,INSM1,LMO2,MEIS2,SLC6A1,SSTR2,CNTN2,ZFPM2" Pubmed 21909369 Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "SLC4A4,BMPR1B,AP4M1,KATNAL1,FGF11,ACTL6B,PRUNE2,MAT2A,DZIP1,SPP1,TAF6" Pubmed 27798109 Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "PLCXD3,HDAC4,EBF1,EGR3,TENM1,ERBB4,GPR26,PTCH1,ARX,MYT1L,TNR" Pubmed 19633665 The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "CALB1,CALB2,TUBB3,GAD1,GFAP,GRM2,NPY,SOX2,SST,SYP,TP53BP1" Pubmed 15632069 The transcription factor gene Nfib is essential for both lung maturation and brain development. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "NRP2,SLIT2,DCC,EMX2,GFAP,L1CAM,NFIA,NFIX,ROBO1,ROBO2,ROBO3" Pubmed 22508726 The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "OLIG2,TUBB3,FGFR1,HES5,SMAD1,SMAD9,NKX2-2,PAX6,MAPK3,SOX2,DICER1" Pubmed 25556712 Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "ASCL1,ELAVL3,ELAVL4,GFAP,GLUL,HES5,NEUROD1,PAX6,RXRG,S100B,SOX2" Pubmed 20615956 Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "FGF17,CRYM,ETV1,TBR1,MEF2C,NHLH1,PAX6,PCDH8,FEZF2,RORB,SOX5" Pubmed 24192035 A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Pubmed 4.55E-05 1.00E+00 7.21E-03 9.32E-02 11 29 "SYN3,APC,TUBB3,GFAP,OMG,OPCML,PAX6,SYT1,UNC5D,TCF4,CA10" Pubmed 23658188 "MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex." Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "MPDZ,CALB2,CDH2,CTNND1,TUBB3,TBR1,SOX2,PARD3,CRB2" Pubmed 19686682 The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ELAVL3,ELAVL4,DLL3,TBR1,GAP43,MAP2,MYCN,PAX6,RELN" Pubmed 12897243 Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "SPAG9,GRIA1,KLC1,MAPK8,MAPK9,SNAP25,MAPK8IP3,STXBP1,SYT1" Pubmed 20399730 The apical complex couples cell fate and cell survival to cerebral cortical development. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "TUBB3,TBR1,MAP2,PAX6,PRKCZ,RELN,CUX2,TSC2,CRB2" Pubmed 22031906 FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "FABP7,TUBB3,FGFR1,FGFR3,TBR1,PAX6,SATB2,ZFPM2,PARD3" Pubmed 22417325 Detection of genes regulated by Lmx1b during limb dorsalization. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "INSYN2B,NOG,COL9A3,COL11A2,EMX2,EFEMP1,SCIN,RFX4,CBLN2" Pubmed 19079260 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "SH2B1,DGKG,NEGR1,KCTD15,FTO,BDNF-AS,TRA2B,FAIM2,CHST8" Pubmed 22090492 Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "CALB1,TUBB3,TBR1,GAD2,NFIX,SOX2,SOX5,SST,CUX2" Pubmed 29879109 METTL3-mediated m6A modification is required for cerebellar development. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ATP2B3,CALB1,DAPK1,GFAP,GRIN1,GRM1,SOX2,METTL3,LRP8" Pubmed 19815519 Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "PTCH2,BMP7,ZNF445,FGFR1,FGFR3,GLI2,PTCH1,SOX6,SOX5" Pubmed 23416452 "mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex." Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ABR,BAIAP3,CALY,MOBP,DRAXIN,TET1,SON,KIF1B,WIPF1" Pubmed 20417196 Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ASCL1,ELAVL3,ELAVL4,GAD1,HES5,NKX2-2,PAX6,SOX2,SLC17A6" Pubmed 16235133 A quantitative survey of gravity receptor function in mutant mouse strains. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "SPTBN4,ATP2B2,QKI,MBP,MYO6,MYO7A,TMIE,POU3F4,PCDH15" Pubmed 17954614 The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "GUCY1A2,GUCY1A1,GUCY1B1,L1CAM,NOS1,NPR2,PRPH,CNTN2,SLC17A7" Pubmed 20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ADCY5,MADD,CRY2,DGKB,GCK,IGF1,PROX1,TCF7L2,AGMO" Pubmed 18723693 "Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice." Pubmed 4.59E-05 1.00E+00 7.21E-03 9.32E-02 9 20 "ADD1,ADD2,ADD3,ANK1,EPB41,DMTN,SPTAN1,SPTB,TMOD1" Pubmed 15475267 Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation. Pubmed 4.62E-05 1.00E+00 7.21E-03 9.32E-02 17 61 "C1QTNF3,ATP1A3,IL33,USP2,CNR1,RCAN2,DUSP27,F3,SLC37A3,GATM,GPT2,ANLN,TMEM38A,PKIA,PYGM,DAAM2,FNDC5" Pubmed 19724895 Association of gene polymorphisms with chronic kidney disease in Japanese individuals. Pubmed 4.62E-05 1.00E+00 7.21E-03 9.32E-02 13 39 "AKAP12,TRAPPC9,ATL1,FAM13A,ACSS1,ACOT7,PCSK2,PIGG,PTPRN2,WDR37,OGDHL,WNK2,JPH3" Pubmed 21319224 Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Pubmed 4.62E-05 1.00E+00 7.21E-03 9.32E-02 13 39 "CALB1,DGKB,DGKG,FABP7,GFAP,PLD5,ENPP2,PRKCG,MAPK3,S100B,SLC1A3,SPHK2,PLD4" Pubmed 12972431 "Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "APBA2,APBB1,APP,CLSTN1,CLSTN2" Pubmed 23097495 LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TUBB3,TBR1,MAP2,MBOAT7,RELN" Pubmed 24236178 Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CDH2,TUBB3,AFDN,S100B,SOX2" Pubmed 26613292 Multiple Src Homology 3 Binding to the Ubiquitin Ligase Itch Conserved Proline-Rich Region. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "BIN1,ARHGEF7,PACSIN1,ITSN1,SH3GL2" Pubmed 25374360 FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "EDIL3,TBR1,UNC5B,UNC5D,FLRT2" Pubmed 16601687 Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DLG4,GRIA1,GRIA2,GRIN1,EXOC7" Pubmed 25231763 Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "BOC,CDON,NKX2-2,PAX6,PTCH1" Pubmed 8863127 Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GFAP,MAP2,RELN,ZIC1,ZIC3" Pubmed 20943905 "Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "KCNA4,KCND2,KCND3,KCNIP3,KCNIP2" Pubmed 8201022 Expression of the tight junction protein ZO-1 in the olfactory system: presence of ZO-1 on olfactory sensory neurons and glial cells. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ENO2,GFAP,L1CAM,MBP,TJP1" Pubmed 20525073 Distinct expression of C1q-like family mRNAs in mouse brain and biochemical characterization of their encoded proteins. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CBLN1,C1QL2,C1QL1,C1QL4,CBLN2" Pubmed 23424281 Impairment of TrkB-PSD-95 signaling in Angelman syndrome. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DLG4,GAB1,NTRK2,ARC,UBE3A" Pubmed 21031554 Composition of the migratory mass during development of the olfactory nerve. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "FABP7,TUBB3,GAP43,DNER,PRPH" Pubmed 7821514 Sox gene expression during neuronal development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ASCL1,PROX1,SOX2,SOX3,SOX11" Pubmed 9069287 Homer: a protein that selectively binds metabotropic glutamate receptors. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "HOMER3,GRIA1,GRIK1,GRM1,GRM5" Pubmed 14704420 Foxg1 suppresses early cortical cell fate. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ETV1,FOXG1,MAP2,RELN,RORB" Pubmed 10331083 Genetic regulation of glutamate receptor ion channels. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GRIA1,GRIA2,GRIK5,GRIN1,GRIN2C" Pubmed 16469306 Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "OLIG2,MBP,NKX2-2,PDGFRA,PLP1" Pubmed 17244534 Ubiquitin binds to and regulates a subset of SH3 domains. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "AMPH,BIN1,DNM1,SH3KBP1,UBC" Pubmed 15878625 Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB1,OLIG1,OLIG2,SOX8,SOX10" Pubmed 12533605 BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GFAP,GLUL,GNAO1,KIF3A,NEUROD1" Pubmed 11359932 Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "MADD,RAB3C,RAB3A,RPH3A,SYN1" Pubmed 25866077 Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GFAP,MAG,MAP2,NCAM1,CADM1" Pubmed 11418862 Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "HOMER3,GRIA1,GRIK1,GRM1,GRM5" Pubmed 18602423 A clathrin-dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell-T cell transmission. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CLTA,CLTB,CLTC,DNM1,DNM2" Pubmed 14734538 "Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "BSN,ERC2,PCLO,RAB3A,RIMS1" Pubmed 20457185 GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5" Pubmed 17178400 The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "OLIG2,GFAP,NFIA,S100B,SLC1A3" Pubmed 11278603 The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "PICK1,ERBB2,GRIN2C,KCNA4,ERBIN" Pubmed 19118189 "Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ARHGEF7,FRMPD4,DLG2,DLG3,DLG4" Pubmed 22378868 Foxg1 has an essential role in postnatal development of the dentate gyrus. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB2,FOXG1,GFAP,PROX1,RELN" Pubmed 23516305 Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TUBB3,NTRK2,NTRK3,PTPRO,RET" Pubmed 18922769 Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GRIA1,GRIA2,GRIA4,GRIK3,GRM1" Pubmed 24214099 Spatiotemporal expression pattern of Myt/NZF family zinc finger transcription factors during mouse nervous system development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ST18,TUBB3,TBR1,MYT1,MYT1L" Pubmed 15897264 "Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "RGS11,RGS9,RGS6,RGS7,RGS7BP" Pubmed 24821223 Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CDH10,DLGAP1,IQCK,GRIK2,PTPRD" Pubmed 24489718 Prdm8 regulates the morphological transition at multipolar phase during neocortical development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TBR1,NEUROD1,PAX6,UNC5D,PRDM8" Pubmed 20503364 Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TUBB3,MYO7A,NEUROD1,SOX2,SOX10" Pubmed 11572861 Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DLG2,DLG3,DLG4,GUCY1A2,GUCY1B1" Pubmed 24706829 Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ?-propeller domain. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ALK,EML1,TUBA1B,TUBB3,EML4" Pubmed 16374801 Neural activity- and development-dependent expression and distribution of CASK interacting nucleosome assembly protein in mouse brain. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CASK,TUBB3,TSPYL2,SYP,TAF9" Pubmed 21838267 The synaptic protein neuroligin-1 interacts with the amyloid ?-peptide. Is there a role in Alzheimer's disease? Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "NLGN4X,APP,NLGN3,NLGN4Y,NLGN1" Pubmed 19573479 Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "XKR4,GFRA2,GRIA4,NPAS3,TNR" Pubmed 9012511 Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "EDN1,EDN3,EDNRA,EDNRB,KITLG" Pubmed 18521090 Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "XKR4,GFRA2,GRIA4,NPAS3,TNR" Pubmed 23979718 JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "MAPK8,MAPK9,MAPK10,MYCBP2,MAP3K12" Pubmed 20037577 HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DNM1,KIF2A,KIF5A,XPO1,TUBA1A" Pubmed 26586761 Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "L1CAM,NELL1,NELL2,ROBO3,CNTN2" Pubmed 11056535 cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "RIMS2,RAPGEF4,RAB3A,RPH3A,RIMS1" Pubmed 8626542 Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SYT6,SYT3,SYT1,SYT4,SYT5" Pubmed 27056679 Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CNR1,GRM2,GRM3,MAPK3,STXBP1" Pubmed 22074847 Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN). Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GPSM1,FRMPD4,NUMA1,GPSM2,FRMPD1" Pubmed 23666762 Role of individual MARK isoforms in phosphorylation of tau at Ser²?² in Alzheimer's disease. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "MARK4,MAPT,MARK1,MARK3,PEG10" Pubmed 16120608 "Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ACTN2,LRRC7,CAMK2A,CAMK2D,CAMK2G" Pubmed 9096138 A hierarchy of Hu RNA binding proteins in developing and adult neurons. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ELAVL2,ELAVL3,ELAVL4,GFAP,PAH" Pubmed 25249462 Ascl1 controls the number and distribution of astrocytes and oligodendrocytes in the gray matter and white matter of the spinal cord. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ASCL1,OLIG2,NFIA,PDGFRA,SOX2" Pubmed 10409510 Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DCC,GLI2,L1CAM,NRCAM,CNTN2" Pubmed 1150661 Alpha hydroxylation of lignoceric acid to cerebronic acid during brain development. Diminished hydroxylase activity in myelin-deficient mouse mutants. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CACNA2D2,QKI,ATP8A2,MYO5A,PLP1" Pubmed 10648716 The lack of Emx2 causes impairment of Reelin signaling and defects of neuronal migration in the developing cerebral cortex. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB2,EMX2,TUBB3,MAP2,RELN" Pubmed 16341215 The claw paw mutation reveals a role for Lgi4 in peripheral nerve development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "LGI1,PLP1,LGI2,LGI3,LGI4" Pubmed 2170109 Structural diversity and evolution of human receptor-like protein tyrosine phosphatases. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "PTPRB,PTPRD,PTPRE,PTPRG,PTPRZ1" Pubmed 11567059 "3-Phosphoglycerate dehydrogenase, a key enzyme for l-serine biosynthesis, is preferentially expressed in the radial glia/astrocyte lineage and olfactory ensheathing glia in the mouse brain." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GAP43,GFAP,MAP2,PLP1,SLC1A3" Pubmed 22832508 High-resolution gene expression atlases for adult and developing mouse brain and spinal cord. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ACHE,GAD1,GFAP,PDYN,SST" Pubmed 20203209 Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ASCL1,GFAP,RBPJ,HES5,S100B" Pubmed 28123425 Ankfy1 is dispensable for neural stem/precursor cell development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "OLIG2,ANKFY1,GLUL,NKX2-2,SLC1A3" Pubmed 23640057 Molecular components required for resting and stimulated endocytosis of botulinum neurotoxins by glutamatergic and peptidergic neurons. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "AP2A2,AMPH,CLTC,DNM1,DNM2" Pubmed 21733846 WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB1,GFAP,NEFH,WNK1,WNK2" Pubmed 18842816 Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SLIT2,TUBB3,ROBO1,ROBO2,SLIT1" Pubmed 15465018 Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ZIC4,ZIC5,MDFI,ZIC1,ZIC2" Pubmed 28445456 Floor-plate-derived netrin-1 is dispensable for commissural axon guidance. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ALCAM,DCC,ROBO1,SOX2,ROBO3" Pubmed 19458237 "Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CNTNAP1,CNTN1,CNTNAP2,L1CAM,CNTN2" Pubmed 15930147 Creatine transporter localization in developing and adult retina: importance of creatine to retinal function. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB1,CALB2,GAD2,GLUL,SLC6A8" Pubmed 27076121 NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "APP,SHC3,MAPK8,MAPK9,MAPK10" Pubmed 23386061 Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DCTN1,CEP170,KIF3A,ODF2,IFT88" Pubmed 12095917 A common protein interaction domain links two recently identified epilepsy genes. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "LGI1,ADGRV1,LGI2,LGI3,LGI4" Pubmed 8617499 Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CHGA,CHGB,GLS,MAP2,SCG2" Pubmed 18768805 Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TUBB3,TBR1,MAP2,POU3F2,RELN" Pubmed 26987813 Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at G?i/o. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "RGS6,GPSM1,GPSM2,RGS4,RGS12" Pubmed 12629181 Widespread defects in the primary olfactory pathway caused by loss of Mash1 function. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ASCL1,GAD1,KITLG,NCAM1,RELN" Pubmed 12767889 Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC8A1" Pubmed 18620078 Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB1,CALB2,GAD1,DISC1,PROX1" Pubmed 15188430 Msx1 disruption leads to diencephalon defects and hydrocephalus. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CALB1,CALB2,GFAP,L1CAM,CNTN2" Pubmed 15033447 "Modelling extracellular domains of GABA-A receptors: subtypes 1, 2, 3, and 5." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GABRA1,GABRA2,GABRA3,GABRA5,GABRG2" Pubmed 27532821 The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "MYRF,MBP,PLP1,DUSP15,SOX10" Pubmed 15034937 Characterizing the new transcription regulator protein p60TRP. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CRLF1,IPO5,PTPA,PPP2R5E,BHLHB9" Pubmed 23187129 "Role of dynamin, synaptojanin, and endophilin in podocyte foot processes." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SYNJ1,DNM1,DNM2,SH3GL2,SH3GL3" Pubmed 10449403 A conformational switch in syntaxin during exocytosis: role of munc18. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CPLX2,CPLX1,SNAP25,STX1A,STXBP1" Pubmed 21751815 "New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "GABRA1,GABRA2,GABRA5,GABRB1,GABRG2" Pubmed 15774481 Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SYT6,STX2,STX1B,STX1A,SYT1" Pubmed 18384059 Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SPARCL1,ASTN1,DLX1,MDGA1,RELN" Pubmed 20877009 A ?(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ANK3,SPTBN4,CACNB2,CAMK2A,CAMK2D" Pubmed 16990550 Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ADAM23,LGI1,DLG4,GRIA2,ADAM22" Pubmed 10764649 Regulation of area identity in the mammalian neocortex by Emx2 and Pax6. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ACHE,CDH8,EMX2,GBX2,PAX6" Pubmed 8576240 "Structures, alternative splicing, and neurexin binding of multiple neuroligins." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "NRXN3,NRXN1,NRXN2,NLGN3,NLGN1" Pubmed 18948074 Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "CAMK2A,CAMK2B,CAMK2D,CAMK2G,MAPK8" Pubmed 11018052 "Agrin isoforms with distinct amino termini: differential expression, localization, and function." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ACHE,SV2B,SV2A,NEFH,SYP" Pubmed 23785143 "A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "AMPH,CLTC,DNM1,PACSIN1,SH3GL2" Pubmed 17360927 Robo1 and robo2 control the development of the lateral olfactory tract. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "SLIT2,L1CAM,ROBO1,ROBO2,SLIT1" Pubmed 20206619 Genetic interaction between Sox10 and Zfhx1b during enteric nervous system development. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ZEB2,FABP7,TUBB3,GFAP,SOX10" Pubmed 21224388 Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ADRB2,CACNA1D,AKAP7,AKAP5,MAP2" Pubmed 12217514 The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "LGI1,ADGRV1,LGI2,LGI3,LGI4" Pubmed 24174661 Netrin-1 promotes excitatory synaptogenesis between cortical neurons by initiating synapse assembly. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "DCC,DLG4,GRIA1,SYN1,SLC17A7" Pubmed 19029029 Control of patterns of corneal innervation by Pax6. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "TUBB3,NTRK2,NTRK3,PAX6,TACR1" Pubmed 27339059 "Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), adenosine receptors (A1 and A2A) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction." Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "ADORA1,ADORA2A,CHRM1,CHRM4,NTRK2" Pubmed 19576965 The distribution and characterization of endogenous protein arginine N-methyltransferase 8 in mouse CNS. Pubmed 4.69E-05 1.00E+00 7.21E-03 9.32E-02 5 6 "APC,GFAP,MAP2,MAPT,PRMT8" Pubmed 22407321 MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Pubmed 4.75E-05 1.00E+00 7.29E-03 9.42E-02 12 34 "SEMA7A,CALB1,VCAN,SEMA3D,MEGF11,MEGF10,GALNT15,GLUL,HAS2,MMP17,NPY,ABCC8" Pubmed 12878157 Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. Pubmed 4.75E-05 1.00E+00 7.29E-03 9.42E-02 12 34 "ALAD,F5,SEMA6C,AHCYL1,KCNK2,CYBC1,FOXRED2,SS18,VAMP1,TCEA1,TRO,FXR1" Pubmed 18590716 FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Pubmed 4.75E-05 1.00E+00 7.29E-03 9.42E-02 12 34 "BMP7,LHX2,OLIG2,TUBB3,GLI2,KIF3A,SMAD1,SMAD9,NKX2-2,PAX6,SOX1,IFT88" Pubmed 22575789 Localization of septin proteins in the mouse cochlea. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "SEPT7,TUBB3,SEPT9,MYO7A,SEPT4,SEPT8,SEPT3,SYP" Pubmed 20016109 Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "CALB1,TUBB3,PPP1R1B,TBR1,GFAP,PAX6,RELN,SST" Pubmed 21518694 PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "CALB1,TUBB3,GAP43,GFAP,PAX6,PCSK5,SYP,CNTN2" Pubmed 14594945 MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "MARK4,MAP2,MAP4,MAPT,MARK1,MARK3,TUBB2A,TUBA1A" Pubmed 23136392 Frs2? enhances fibroblast growth factor-mediated survival and differentiation in lens development. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "ALK,ETV1,NTRK2,NTRK3,PAX6,MAPK3,PROX1,RET" Pubmed 11404013 Molecular evolution of Sry and Sox gene. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "SOX6,SOX1,SOX2,SOX3,SOX5,SOX10,TCF4,UBTF" Pubmed 19451621 Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "SEMA6A,B4GALT6,CSNK1G3,EFEMP1,DISC1,ATXN1,SCN7A,SELL" Pubmed 21338885 Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "ASCL1,CALB2,TBR1,GAD1,FEZF2,LIMCH1,SST,SATB2" Pubmed 12590134 Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "MYRIP,SYTL4,SYTL2,RAB3A,RPH3A,SNAP25,STX1A,STXBP1" Pubmed 12930780 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "ASCL1,CALB1,EBF1,OLIG2,GAD1,PAX6,PDGFRA,PLP1" Pubmed 16860307 Laminar organization of the early developing anterior hypothalamus. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "ALCAM,CBLN1,LDB2,NKX2-2,PDZRN4,POU3F2,RGS4,TRH" Pubmed 22090484 A wide diversity of cortical GABAergic interneurons derives from the embryonic preoptic area. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "CALB1,CALB2,TBR1,NKX6-2,NOS1,NPY,RELN,SST" Pubmed 22461901 "Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse." Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "BMP7,TBR1,GAD1,MAP2,NEUROD1,PAX6,RELN,SOX2" Pubmed 24799694 Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "CALB1,CALB2,EBF1,FOXG1,GAD1,GAD2,GFAP,FZD3" Pubmed 16055064 PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "AP2A1,AP2A2,PICK1,GRIA1,GRIA2,GRIA4,PRKCB,PRKCG" Pubmed 19805360 The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "DCT,FABP7,L1CAM,MBP,NTRK2,PMP22,RET,SOX10" Pubmed 16061358 Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "ASCL1,MAML1,DAPK1,TUBB3,RBPJ,HES5,HEY1,HEY2" Pubmed 27223328 NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "PTBP2,DCC,EPHA5,NOVA1,NOVA2,SOX2,ROBO3,CNTN2" Pubmed 21510873 The role of the transcription factor Rbpj in the development of dorsal root ganglia. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "FABP7,TUBB3,STMN2,RBPJ,NEUROD1,NTRK2,NTRK3,SOX10" Pubmed 20808911 A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "DLGAP1,SLC12A6,ELAVL4,NSG1,KIF5A,PALM,STAU1,SYT1" Pubmed 18501628 BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood-brain-barrier. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "CALB2,NCAN,GFAP,MAG,MAP2,MBP,S100B,SLC1A2" Pubmed 25082827 A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis. Pubmed 4.82E-05 1.00E+00 7.29E-03 9.42E-02 8 16 "BSN,IP6K1,IP6K2,GPD2,PFKFB4,INAVA,KIF21B,ACTR3B" Pubmed 10591208 The DNA sequence of human chromosome 22. Pubmed 4.84E-05 1.00E+00 7.32E-03 9.46E-02 51 299 "SYN3,ELFN2,PLA2G6,MRTFA,MTMR3,CACNA1I,P2RX6,LARGE1,FBXO7,FAM19A5,TMEM184B,SULT4A1,PICK1,CRYBB1,CSNK1E,PPP6R2,TOM1,CACNG2,TUBA8,CSDC2,GGT5,MCHR1,GSTT2,PACSIN2,KCNJ4,MGAT3,ZDHHC8,POLR2F,PPARA,CASTOR1,KCTD17,MAPK12,SBF1,PEX26,SMTN,SOX10,SEPT3,MLC1,KIAA0930,CABIN1,RBFOX2,SEZ6L,RASD2,TST,PITPNB,OSBP2,BCL2L13,ZNF74,POLR3H,TFIP11,HPS4" Pubmed 23703321 A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors. Pubmed 5.00E-05 1.00E+00 7.56E-03 9.77E-02 15 50 "ATM,PLAA,TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,HSPA1L,HSP90AA1,PFKP,PKM,CNTLN,GANAB,TUBA1A,NAV2" Pubmed 12819125 Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Pubmed 5.12E-05 1.00E+00 7.73E-03 9.99E-02 41 224 "ADAR,MYH7B,ATP1A2,MYOM1,RUNX1T1,CCNH,TBRG4,CPS1,PUM1,MYADM,DNAJC6,DMTN,SEPT9,WASHC2A,GPR12,HPCA,IL11RA,ITIH2,KLC1,IPO5,NFE2L2,OGDH,P2RY1,RETREG1,PRODH,C1orf109,RXRG,SGK1,SPHKAP,SNCA,GSE1,SYN2,DDHD2,TCF4,TPM3,XRCC4,ZIC3,TCEAL7,CAB39L,RSPRY1,RNF146" Pubmed 15840729 Scanning the human proteome for calmodulin-binding proteins. Pubmed 5.19E-05 1.00E+00 7.73E-03 9.99E-02 22 92 "ACADM,DOCK11,DST,SCAPER,CALM1,AKAP6,MATR3,ZBTB24,CASP8AP2,OPTN,USP16,GNAS,OPALIN,MYBPC1,RDX,CLIP1,S100B,MYCBP2,KIF1B,SYNE2,CCDC14,XRCC4" Pubmed 14598259 Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB2,GFAP,NPY,PRPH,SST,TAC1" Pubmed 18703590 The transcription factor Sox5 modulates Sox10 function during melanocyte development. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DCT,KIT,MITF,SOX6,SOX5,SOX10" Pubmed 10512984 Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "APC,CALB1,TUBB4A,GFAP,MBP,NCAM1" Pubmed 21117150 Sox11 regulates survival and axonal growth of embryonic sensory neurons. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,NTRK2,NTRK3,RET,SOX10,SOX11" Pubmed 19000783 Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TBR1,L1CAM,AFF1,PAX6,RELN,CUX2" Pubmed 22266424 Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ACHE,FABP7,TUBB3,S100B,SOX10,UCHL1" Pubmed 12297500 G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ADCY5,ADCY6,ADRB2,KCNJ3,KCNJ5,KCNJ9" Pubmed 25378163 Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor ? family proteins during corticogenesis. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "BMP7,OLIG2,SMAD1,SMAD9,PDGFRA,PROX1" Pubmed 27878595 Cell-type-specific expression of NFIX in the developing and adult cerebellum. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB1,CALB2,OLIG2,GFAP,NFIX,PAX6" Pubmed 17938206 "The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity." Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CASK,MAGI1,DLG3,DLG4,MPP6,MPP2" Pubmed 25056828 Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "SLIT2,DCC,TUBB3,ROBO1,ROBO2,SLIT1" Pubmed 27713499 "Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits." Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB2,SLC32A1,GAD1,GFAP,SST,SLC17A7" Pubmed 17332510 Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ASCL1,OLIG1,EGFR,OLIG2,GAB1,NKX2-2" Pubmed 23483698 Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,MYCN,NEUROD1,MAPK3,PROX1,SOX11" Pubmed 9914469 Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "SYT3,RAB3A,NAPB,SYT1,SYT4,SYT5" Pubmed 9278515 Binding of neuroligins to PSD-95. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "NLGN4X,DLG2,DLG3,DLG4,NLGN3,NLGN1" Pubmed 10899153 Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DPP6,EN2,GABRB1,HTR5A,KCNK3,QDPR" Pubmed 17526495 Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DLG3,DLG4,FYN,GRIN1,GRIN2C,GRIN2D" Pubmed 12629171 Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "PPFIA4,PPFIA2,PPFIA1,PTK2B,GIT1,PTK2" Pubmed 12660151 Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ATP2B1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,PPP3CA" Pubmed 10531343 "Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X." Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "SYT6,SYT3,SYT9,SYT11,SYT4,SYT5" Pubmed 20653027 Molecular regulation of the developing commissural plate. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "EMX2,GAP43,GFAP,NFIA,SATB2,ZIC2" Pubmed 12186854 Notch1 control of oligodendrocyte differentiation in the spinal cord. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,GFAP,MAG,MBP,PDGFRA,PLP1" Pubmed 16407767 Distinct developmental expression of synaptotagmin I and IX in the mouse brain. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "SYT6,SYT3,SYT9,SYP,SYT1,SYT5" Pubmed 19146812 The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "APC,NUMB,CALB2,FABP7,TBR1,L1CAM" Pubmed 19321785 E-Cadherin regulates neural stem cell self-renewal. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "PROM1,CDH2,CTNND1,GFAP,NCAM1,SOX2" Pubmed 11784856 The neuronal basic helix-loop-helix transcription factor NSCL-1 is dispensable for normal neuronal development. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB1,CALB2,GFAP,STMN2,NEUROD1,NHLH1" Pubmed 16554481 Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DLG4,GRIN3A,GRIN1,GRIN2C,GRIN2D,NR3C1" Pubmed 12644247 "Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin." Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB1,CALB2,DLX1,EMX2,TBR1,RELN" Pubmed 25232112 Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CDH2,DLG4,TBR1,GRIA1,POU3F2,SYP" Pubmed 9834195 Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ENO2,TUBB3,GFAP,NPY,RET,S100B" Pubmed 23457482 Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "UNC5A,GFAP,UNC5B,UNC5D,RGMB,RGMA" Pubmed 18551627 Development of satellite glia in mouse sympathetic ganglia: GDNF and GFR alpha 1 are not essential. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "FABP7,GFRA1,NCAM1,RET,S100B,SOX10" Pubmed 14622577 Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CASK,BSN,CDH2,DLG4,SYN1,SYP" Pubmed 16710293 NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ACTN2,AP2A1,CAMK2A,DLG4,GRIN1,RASGRF1" Pubmed 19037081 Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CDK5R1,CALB1,CALB2,GAD1,RELN,SST" Pubmed 11835375 Charcot-Marie-Tooth disease and related neuropathies: mutation distribution and genotype-phenotype correlation. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "PRX,MTMR2,GJB1,PMP22,PRPH,KIF1B" Pubmed 16916601 Genetic modifiers of muscular dystrophy: implications for therapy. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DMD,MSTN,IGF1,ITGA7,LAMA2,NOS1" Pubmed 24582971 Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "GAP43,GFAP,NCAM1,NPY,PRPH,S100B" Pubmed 27384060 Foxp2 Regulates Identities and Projection Patterns of Thalamic Nuclei During Development. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CALB2,LHX2,GAD1,GBX2,NTNG1,SLC17A6" Pubmed 11032813 Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ASCL1,CALB1,GFAP,MAP2,NEUROD1,S100B" Pubmed 18308723 Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "MAP7,CREM,B4GALNT1,KIT,CLDN11,TJP1" Pubmed 19389366 Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "FABP7,TUBB3,GFAP,MBP,RELN,S100B" Pubmed 22293606 DYRK1A: a master regulatory protein controlling brain growth. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DYRK1A,GAP43,GFAP,MAP2,SNAP25,SYP" Pubmed 20093372 Nogo-a regulates neural precursor migration in the embryonic mouse cortex. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,TBR1,LINGO1,TNFRSF19,SATB2,RTN4" Pubmed 22071102 The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "EGFR,FGFR3,GFAP,NKX2-2,PAX6,PDGFRA" Pubmed 27480591 Cdk5 is required for the positioning and survival of GABAergic neurons in developing mouse striatum. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CDK5R1,CDK5R2,PPP1R1B,GFAP,MAPK3,MAPK8" Pubmed 19580868 Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CCK,CDHR1,GRM1,NCAM1,PAX6,UCHL1" Pubmed 26403076 Behavioral phenotypes of genetic mouse models of autism. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "NRXN1,CNTNAP2,SHANK1,NLGN3,NLGN1,SHANK2" Pubmed 27023172 "Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse." Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DLG4,GAD1,GFAP,MAPT,KDM4B,KDM4C" Pubmed 20804972 Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "ASCL1,DYRK1A,EGFR,TUBB3,GFAP,SOX2" Pubmed 18184726 Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "OLIG2,MBP,NKX2-2,PDGFRA,PLP1,SOX10" Pubmed 20566868 Liver X receptor beta and thyroid hormone receptor alpha in brain cortical layering. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,TBR1,POU3F2,RELN,THRA,LRP8" Pubmed 24292102 Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "CHRM1,DRD1,GRIA1,GRIA2,GRIA4,GRIN1" Pubmed 24013503 Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "TUBB3,PRMT5,TBR1,GFAP,MDM4,SOX2" Pubmed 19777589 Neural stem cell self-renewal requires the Mrj co-chaperone. Pubmed 5.31E-05 1.00E+00 7.73E-03 9.99E-02 6 9 "DNAJB6,OLIG2,STMN2,HES5,NKX2-2,PAX6" Pubmed 25544563 Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Pubmed 5.49E-05 1.00E+00 7.99E-03 1.03E-01 80 533 "RALGAPA1,KIDINS220,OSBPL6,OSBPL8,TAOK1,AMPD2,ANXA7,EPB41L5,APP,DPY19L3,ATP6V0A1,BLM,WASF1,FOXK1,TRIM41,CANX,CDC27,TBRG4,TPP1,TJP2,ARMC8,COX4I1,AKAP12,ANKRD44,CS,OSBPL3,PPP6R2,B3GAT3,POM121,DNM1L,GOLT1B,EPB41,RABEPK,SRRM1,TAOK3,FECH,AGAP3,ZCCHC17,ATP6V1H,NEURL4,WASF3,OS9,NUDT21,ATE1,IL6ST,KPNA5,MKLN1,NEK1,OGDH,PDE3B,SERPINE2,MBOAT7,TNPO2,MAPK3,NCR3LG1,KCTD17,MRPS18A,ARMC5,RPS6KA2,FBXO11,RAB3GAP1,CDK5RAP3,KDM3A,MYCBP2,EPB41L3,GANAB,ANKRD28,EXOC7,CAMSAP2,KLHL4,DAAM2,KCTD2,ZNF346,HIRA,FTSJ1,FIP1L1,MARCH8,NUP214,VANGL2,NHSL1" Pubmed 21884692 Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Pubmed 5.50E-05 1.00E+00 7.99E-03 1.03E-01 16 56 "ACTN2,HHATL,ATP2A2,HDAC4,GLI2,MEF2C,MYH3,MYH7,NEFH,NOS1,PGAM2,MAPK3,SOX6,SYP,TNNT1,HRASLS" Pubmed 23934736 Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Pubmed 5.50E-05 1.00E+00 7.99E-03 1.03E-01 16 56 "SORCS1,CADPS,CACNA2D1,CNTN1,DKK3,ICA1,CTNNA3,MYO5A,TRHDE,RELN,ANKRD6,CDK5RAP3,TPD52,FAM155A,ZNF213,PRTFDC1" Pubmed 23088713 Protein interactions of the transcription factor Hoxa1. Pubmed 5.79E-05 1.00E+00 8.41E-03 1.09E-01 17 62 "OGT,RGS20,RAB33A,FHL5,PDCD6IP,RGS17,BSCL2,PRRC2B,C1orf94,LIMS1,MDFI,PBX1,PCSK5,SMOC1,MGAT5B,ZBTB16,PLSCR4" Pubmed 26212757 Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "ACTN2,CDH2,ZEB2,RAPGEF1,AFDN,PRKCZ,RAP1GAP,RAP1GDS1,ZEB1,TJP1" Pubmed 25810530 The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/?-catenin signaling. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "AXIN2,APC,OLIG2,NKD1,SMAD1,MBP,PDGFRA,PLP1,SOX10,TCF7L2" Pubmed 27578777 Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "ASCL1,FGF17,CALB2,EFNA2,EN2,TUBB3,GBX2,PAX6,MAPK3,SOX2" Pubmed 23042297 Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "ASCL1,DLX1,EBF1,OLIG2,GAD1,NKX6-2,SALL3,HES5,PBX1,ARX" Pubmed 26809587 The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "CDH2,CLTC,EDIL3,EMX2,EN2,NKX2-2,PDPK1,PRKCZ,TJP1,PARD3" Pubmed 19279220 "An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency." Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "ARID1A,BCL7A,NUMA1,DPF2,PBRM1,SFPQ,SMARCA4,SMARCC2,SMARCD3,SMARCE1" Pubmed 21300867 Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "BMP7,NTM,IGSF21,NEFH,NTRK2,NTRK3,RET,TRPC3,UCHL1,SLC17A7" Pubmed 19749747 AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex. Pubmed 5.93E-05 1.00E+00 8.57E-03 1.11E-01 10 25 "ASCL1,ETV1,TUBB3,TBR1,L1CAM,NEUROD1,PAX6,SLC1A3,CUX2,SLC17A6" Pubmed 17971504 Tissue expression patterns identify mouse cilia genes. Pubmed 6.18E-05 1.00E+00 8.92E-03 1.15E-01 22 93 "NME5,CCDC146,CCDC181,CCDC151,LRRC23,ZMYND10,CFAP126,PACRG,ERICH3,PMP22,HYDIN,RFX2,KIF27,HSPA4L,CABCOCO1,TSNAXIP1,ENKUR,PPIL6,CFAP52,DNALI1,MDH1B,AMN1" Pubmed 1628813 Rat gene mapping using PCR-analyzed microsatellites. Pubmed 6.24E-05 1.00E+00 9.01E-03 1.16E-01 13 40 "ADRB2,AGT,ASGR1,NR3C1,HP,IGF1,MBP,MYL3,NPY,NPPA,PRKCG,PTHLH,SST" Pubmed 17151600 Genome-wide atlas of gene expression in the adult mouse brain. Pubmed 6.45E-05 1.00E+00 9.31E-03 1.20E-01 15 51 "SLC4A4,NCOR1,DCC,ETV1,FOXG1,GAD2,GBX2,HNF4G,KIT,ARX,SLC1A3,SLC1A6,CUX2,HEY2,SLC17A6" Pubmed 15755804 Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "AXIN2,EPB41L5,HECTD1,ABI1,NCKAP1,KIF3A,OPA1,PAX6,IFT122,TTBK2,IFT88" Pubmed 24302887 "Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton." Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "AXIN2,WDPCP,OLIG2,DKK3,GLI2,NKD1,PAX6,PTCH1,WLS,VANGL2,IFT88" Pubmed 16306228 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK. Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "MARK4,BRSK2,USP2,BRSK1,HSP90AA1,MARK1,MARK3,PRKAB2,SNRK,SIK3,TUBA1A" Pubmed 20306291 A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "TMCC3,CARS,BOC,RGS17,FOXO3,IDH3A,CTNNA3,IRX1,RXRA,FERMT1,PDZRN3" Pubmed 22837378 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "SEMA7A,CREB5,CALN1,EMX2,SEPT9,PCDH8,PTPRD,WLS,SEZ6L,ST8SIA2,SPATA13" Pubmed 20083228 Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India. Pubmed 6.55E-05 1.00E+00 9.41E-03 1.22E-01 11 30 "DCC,EDN1,DLC1,FGF12,KCNH1,KCNK2,NCAM1,NTRK2,TLR4,TRIO,WNT7A" Pubmed 11416179 "All kinesin superfamily protein, KIF, genes in mouse and human." Pubmed 6.59E-05 1.00E+00 9.46E-03 1.22E-01 12 35 "KIF6,KIF1A,KIF26A,KIF19,KIF3A,KIF2A,KIF7,KIF21A,KIF16B,KIF13A,KIF21B,KIF1B" Pubmed 22688191 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Pubmed 6.59E-05 1.00E+00 9.46E-03 1.22E-01 12 35 "ANK3,ADAM23,PTBP2,FEZ1,KCNMB2,DLC1,MMP16,MSRA,CNNM2,PKNOX2,TCF4,CSMD1" Pubmed 20301590 Nonsyndromic Retinitis Pigmentosa Overview Pubmed 6.91E-05 1.00E+00 9.91E-03 1.28E-01 20 81 "SLC7A14,BBS2,PROM1,CA4,C8orf37,ADGRA3,AGBL5,IDH3B,NEUROD1,RGR,RLBP1,ROM1,RPE65,PRCD,SPATA7,EMC1,KLHL7,SEMA4A,CRB1,BEST1" Pubmed 19351817 Genetic mutations associated with cigarette smoking in pancreatic cancer. Pubmed 7.22E-05 1.00E+00 1.04E-02 1.34E-01 17 63 "APC,ATM,CSF1R,EGFR,ERBB2,FGFR3,GNAS,PTPRT,JAK2,KIT,NF1,NTRK3,PDGFRA,PIK3R1,PTCH1,RET,FBXW7" Pubmed 16923123 Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. Pubmed 7.27E-05 1.00E+00 1.04E-02 1.35E-01 18 69 "RAB29,USP6,EVI5L,RAB3C,RAB33A,RAB28,RAB26,RABGAP1L,RAB39B,RAB9B,RAB30,RAB40B,TBC1D25,RAB39A,RAB3A,RAB5B,RAB3GAP1,TBC1D15" Pubmed 8827514 Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. Pubmed 7.31E-05 1.00E+00 1.04E-02 1.35E-01 24 107 "CDO1,CLU,CPS1,DCAF8,DAPK1,ENO2,F3,FDFT1,ERGIC3,GAD2,GHR,DHRS4,GRIA4,HMGCR,NPPA,PAH,PLP1,POU3F4,POU6F1,PPARA,RXRG,SCP2,SELL,VLDLR" Pubmed 18593464 Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "DDR1,CSF1R,EPHB1,FGFR1,FLT1,KIT,TEK,TIE1,TNFRSF1B" Pubmed 23284715 Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "CLDN10,CHN1,CD320,GPM6A,GPM6B,VSIG4,OCIAD1,ATP13A2,PMEPA1" Pubmed 24167708 The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "ASCL1,ELAVL3,ELAVL4,GAD1,NKX2-2,PAX6,SOX2,TAL1,SLC17A6" Pubmed 15452121 "A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP)." Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "ADRB2,CHRM1,CHRM4,GPRASP1,GRM1,GRM5,GRM8,OXTR,TACR1" Pubmed 16038893 Multiple requirements for Hes 1 during early eye formation. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "ASCL1,DCT,DLX1,TUBB3,B3GAT1,MITF,NEUROD1,PAX6,RXRG" Pubmed 28289129 Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "ASCL1,CALB1,DLX1,EBF1,PPP1R1B,GFAP,MAP2,PENK,TAC1" Pubmed 21205789 Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "AXIN2,BMP7,TUBB3,HES5,MITF,NEUROD1,PAX6,SOX2,ZIC1" Pubmed 23790753 SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "BRSK2,ETV1,TUBB3,BRSK1,MAPT,NEFH,NTRK3,MAPK3,SLC17A7" Pubmed 22114277 The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "GRIN3A,GRIN1,GRIN2C,GRIN2D,PRKACB,PRKCB,PRKCG,PRKCZ,SMPD3" Pubmed 22522401 Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Pubmed 7.34E-05 1.00E+00 1.04E-02 1.35E-01 9 21 "ATM,CALB1,FABP7,TUBB3,TBR1,GFAP,LIG4,POU3F2,SATB2" Pubmed 21150319 Proteomic profiling of Myc-associated proteins. Pubmed 7.73E-05 1.00E+00 1.10E-02 1.42E-01 25 114 "EP400,CALM1,CAMK2D,NRXN3,AKAP6,SEC31B,CTNND1,RIMS2,SPEG,ECSIT,RBPJ,KNDC1,OPA1,ROBO2,SMTN,RCOR3,PDZD2,ERC1,ERBIN,GANAB,TCF12,TF,TSN,UBC,UBTF" Pubmed 12376551 RhoG signals in parallel with Rac1 and Cdc42. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CDC42,IQGAP2,MCF2L,ARHGEF12,TIAM1,VAV1,VAV2" Pubmed 12194848 "Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families." Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "SOX21,SOX1,SOX2,SOX3,SOX5,SOX11,SOX15" Pubmed 25100583 Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CDH2,TUBB3,GFAP,L1CAM,AFDN,PAX6,CNTN2" Pubmed 20624980 Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "SEMA7A,APAF1,BSN,TUBB3,NCAM1,NCAM2,SYP" Pubmed 20473291 "Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus." Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CELSR3,GFAP,MDGA1,SSPO,TJP1,FZD3,VANGL2" Pubmed 21339379 Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "FGF14,GABRG2,GRIA2,L1CAM,NTRK2,MAPK3,SCN2A" Pubmed 16476661 The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB1,CALB2,ETV1,TBR1,GAD1,PAX6,SLC1A3" Pubmed 29045729 Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB1,CALB2,KIAA0319,NEFH,PAX6,RELN,SST" Pubmed 15902206 Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB2,EFNA2,EFNA3,TUBB3,TBR1,MAP2,RELN" Pubmed 22442076 Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB1,CALB2,GAD1,NCAM1,MAPK7,RELN,SOX2" Pubmed 25135772 Neonatal lethality of neural crest cell-specific Rest knockout mice is associated with gastrointestinal distension caused by aberrations of myenteric plexus. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "ACHE,TUBB3,GFAP,SOX1,SOX10,SYP,SYT4" Pubmed 8441686 Seven new members of the Sox gene family expressed during mouse development. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "SOX8,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11" Pubmed 20643355 Epicardial spindle orientation controls cell entry into the myocardium. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "NUMB,CDH2,PARD6A,PRKCZ,TJP1,PARD3,TUBA1A" Pubmed 11306624 Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "LHX2,TUBB3,GBX2,MAP2,NKX2-2,PAX6,PTPRG" Pubmed 11934853 Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "ASCL1,LHX2,EBF1,DLL3,STMN2,HES5,NEUROD1" Pubmed 17108173 The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB2,TUBB3,MAP2,MAPT,MAPK8,RELN,MAP3K12" Pubmed 24327562 A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "DLG4,TUBB3,FOXG1,GRIA2,MYO7A,NEFH,SYP" Pubmed 20040495 Role of Fgf8 signalling in the specification of rostral Cajal-Retzius cells. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB2,EMX2,ETV1,FOXG1,TBR1,PAX6,RELN" Pubmed 22569571 Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "ADRA1B,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,HTR2A" Pubmed 18625210 Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "PTCH2,CDC25B,OLIG1,GFAP,MBP,PDGFRA,PTCH1" Pubmed 22304922 Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "EFNA2,OLIG2,EPHA5,TUBB3,GFRA1,NTRK2,RET" Pubmed 23575831 Lmo4 establishes rostral motor cortex projection neuron subtype diversity. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "LDB2,LHX2,OLIG2,GAD1,GFAP,KITLG,RORB" Pubmed 28482867 Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "PROM1,CDH2,CTNND1,AFDN,PAX6,TJP1,PARD3" Pubmed 18786638 Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CDK5R1,CALB1,CALB2,CREM,MAPT,PROX1,RELN" Pubmed 24355921 Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB1,HAP1,GFAP,GRIA2,MBP,NTRK2,SOX2" Pubmed 22640814 Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "ADRA1B,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,HTR2A" Pubmed 27163549 Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "ENTPD4,OPALIN,NPY,PSAT1,ZFHX4,NKAIN2,ZBTB16" Pubmed 26235615 Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "CALB1,CDH2,TBR1,FYN,RELN,CUX2,TSC2" Pubmed 21873192 Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "NDRG2,BEND6,ZNF608,ARHGEF25,NSG2,MYT1,SOX11" Pubmed 10520995 "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates." Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "SEMA7A,NRP2,PLXNA4,PLXNC1,SEMA4D,PLXNB1,PLXNB3" Pubmed 28137836 DSCAM promotes axon fasciculation and growth in the developing optic pathway. Pubmed 8.02E-05 1.00E+00 1.12E-02 1.45E-01 7 13 "DSCAML1,DSCAM,TUBB3,NRCAM,SLIT1,CNTN2,ZIC2" Pubmed 26618866 ?F508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Pubmed 8.21E-05 1.00E+00 1.14E-02 1.48E-01 92 640 "ACLY,ACTN1,ACTN2,SORCS1,ESYT2,AP1B1,MYH7B,PDXK,CCAR2,ATP2A2,ATP2B1,CALM1,CANX,CAST,CBR1,AIFM1,LRBA,SEPT7,COPB2,CLTC,AKAP12,SEC24C,PABPC5,DBN1,DCTN1,SEC16A,DNM2,DNAJB6,EGFR,SRRM1,ACSL4,TUBB3,RACK1,FHL1,ATP5PD,SEC23B,DCTN2,ERAP1,TUBA8,GSN,IDH3A,IDH3B,ITIH2,MAT2A,MOV10,DBNL,CCDC80,MX1,MYH3,MYH6,MYH7,MYO6,HNRNPM,NAP1L1,PCBP3,PCMT1,TMOD2,PGAM2,PKM,PLEC,PPP2R2B,PSMA6,RAB5B,RDX,ZYG11B,RNH1,MYH14,RPL15,HSPA4L,MYO18A,SMARCC2,LIMCH1,SPTAN1,MPRIP,STAU1,TTBK2,GANAB,PRRC2C,MMS19,EXOC7,ALG1,TF,TP53BP1,TPM1,TPM2,TPM4,TUBB1,UBTF,TBC1D15,XPO1,SNX27,ACTR3B" Pubmed 14595844 Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Pubmed 8.26E-05 1.00E+00 1.15E-02 1.48E-01 15 52 "AP1B1,CBLN1,COL9A3,MAGED1,PUM1,ING4,USP19,GNAS,MEST,NACA,SERPINE2,SS18,TPM3,WRN,ITM2C" Pubmed 20935640 Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "FABP7,TBR1,GFAP,MSI1,POU3F2,FBXW7,S100B,SLC1A3" Pubmed 26212322 "miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability." Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "ELAVL2,EN2,TUBB3,FOXG1,GBX2,HES5,NKX2-2,PAX6" Pubmed 21316586 Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "DCC,CELSR3,L1CAM,NKX2-2,MAPK8,CNTN2,FZD3,VANGL2" Pubmed 19244520 The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "CALB2,LHX2,TUBB3,GBX2,GFAP,NEUROD1,NKX2-2,PTCH1" Pubmed 22028030 "Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex." Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "DPY19L3,DCTN4,TUBB3,TBR1,GAD1,ZC3H14,SCMH1,CNTN2" Pubmed 20200953 Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "CBLN1,SLC35F1,RAPGEF4,LMO1,NELL1,PTPRD,SCG2,FAM13C" Pubmed 23404109 Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "ASCL1,OLIG2,TBR1,MAP2,PAX6,RELN,RLBP1,ZIC1" Pubmed 20627871 Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "RGS20,RGS11,RGS9,RGS3,RGS4,RGS7,RGS10,RGS12" Pubmed 16774995 "A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography." Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "PCDH10,CALB1,CDH8,EBF1,FABP7,GFAP,RELN,SLC1A3" Pubmed 23426694 Gata3 is a critical regulator of cochlear wiring. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "PCDH19,SPARCL1,CHRDL1,TUBB3,MYH6,NEFH,NTNG1,RGS7BP" Pubmed 22837015 Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "CALB2,ELAVL2,ELAVL3,ELAVL4,TUBB3,MAP2,PAX6,UCHL1" Pubmed 15677725 Arx homeobox gene is essential for development of mouse olfactory system. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "NRP2,L1CAM,NCAM1,NCAM2,NPY,RELN,ARX,SLC1A3" Pubmed 19503085 HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "APC,OLIG1,OLIG2,GFAP,MBP,PDGFRA,PLP1,TCF7L2" Pubmed 23284756 Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "ASCL1,TUBB3,TUBB4A,KIT,NCAM1,SOX2,TJP1,UCHL1" Pubmed 24086760 Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "GRIN3A,GRIN1,GRIN2C,GRIN2D,KCNB1,PPP3CA,PPP3CB,PPP3CC" Pubmed 23022035 p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "CALB1,PARD6A,TUBB3,GAD1,GSN,NPY,SST,CUX2" Pubmed 1676978 Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "ADRA1D,ADRA1B,ADRB2,EGFR,ERBB2,NR3C1,MBP,THRA" Pubmed 29483282 BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "APC,OLIG2,F3,TUBB3,ALDH1L1,GFAP,ITGAM,S100B" Pubmed 14506234 "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton." Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "WASF1,DBN1,DNM1,EVL,NCKAP1,DNMBP,TUBA1A,WIPF2" Pubmed 23001562 Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "MPDZ,CDH2,CTNND1,GFAP,GLUL,CRB1,PARD3,CRB2" Pubmed 22832960 A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Pubmed 8.33E-05 1.00E+00 1.15E-02 1.48E-01 8 17 "CSMD3,APBA2,NRXN1,PCDH18,PTPRD,SLA,CADM2,MSRB3" Pubmed 23383108 Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1. Pubmed 8.54E-05 1.00E+00 1.17E-02 1.52E-01 24 108 "ADORA3,OSBPL1A,C1QTNF1,APOC1,ASGR1,CA12,VCAN,SDC3,ARNT2,HS3ST2,TLR7,SIRPB1,F3,FOLR2,DNER,GPR34,VSIG4,INSM1,KCNJ5,NDP,TREM2,RNASE1,ASRGL1,SCG5" Pubmed 24029230 "Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7." Pubmed 8.68E-05 1.00E+00 1.19E-02 1.54E-01 19 76 "KCNAB2,ARHGEF7,PYGO1,SIRPA,ZBTB24,EML1,BVES,DOCK7,ITGAM,PDGFRA,ANLN,SAMD9,PTPRZ1,SMPD3,SLC8A3,PRRC2C,WDR7,SIGLEC10,PLD4" Pubmed 26073538 Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pubmed 8.68E-05 1.00E+00 1.19E-02 1.54E-01 22 95 "ABCF1,GRAMD1B,PKP4,RASSF2,TRAPPC9,ATP8A2,ADAMTS13,ADAMTS8,SOX21,ZDHHC15,MYO5A,MYO6,ABCB1,PPP3CC,PKN2,ALG9,WDR37,SOX2,ALG1,WNK1,RGMA,TTC7A" Pubmed 11140838 A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory. Pubmed 8.76E-05 1.00E+00 1.20E-02 1.55E-01 16 58 "ADORA2A,CCK,CNR1,DRD1,EPHB1,GABBR1,GABRA1,GABRA3,GABRA5,GABRB1,GABRB3,GAD1,GRIN1,HTR2A,OXTR,PENK" Pubmed 19026994 Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord. Pubmed 8.80E-05 1.00E+00 1.20E-02 1.55E-01 10 26 "RNF157,PPFIA3,HIP1R,SEC24C,KIAA0319,TUBB3,KIF1B,FSTL5,NAV2,NUP214" Pubmed 26628093 Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Pubmed 8.80E-05 1.00E+00 1.20E-02 1.55E-01 10 26 "BMP7,CALB1,CDH2,GLUL,WIF1,MITF,PAX6,SMARCA4,TJP1,PARD3" Pubmed 22345400 The transcription factor c-Maf controls touch receptor development and function. Pubmed 8.80E-05 1.00E+00 1.20E-02 1.55E-01 10 26 "CALB1,CALB2,FABP7,KCNA1,NEFH,NTRK2,NTRK3,PRPH,RET,UCHL1" Pubmed 25820252 Interactome of the negative regulator of nuclear import BRCA1-binding protein 2. Pubmed 8.80E-05 1.00E+00 1.20E-02 1.55E-01 10 26 "BRAP,ZNF521,RBM12,AKAP3,NUMA1,FAM184A,SMARCE1,SYNE2,ATMIN,UBC" Pubmed 11044607 Large-scale screen for genes involved in gonad development. Pubmed 8.91E-05 1.00E+00 1.20E-02 1.55E-01 18 70 "FUBP1,TBRG4,CNRIP1,CST3,GAPVD1,MED24,GLYR1,AFDN,PTOV1,HNRNPM,PDGFRA,PSAT1,PRRX1,MYO18A,CDK5RAP3,PEG10,KIF1B,PJA1" Pubmed 24523460 Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Pubmed 9.02E-05 1.00E+00 1.20E-02 1.55E-01 12 36 "ASCL1,BMP7,LHX2,TUBB3,B3GAT1,SMAD1,NEUROD1,PAX6,MAPK3,PROX1,RXRG,SOX2" Pubmed 15717329 Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics. Pubmed 9.02E-05 1.00E+00 1.20E-02 1.55E-01 12 36 "G3BP2,MED12,EEF1A2,PTK2B,GFRA2,PDGFRA,PTPA,PKN2,PTK2,SMTN,ARHGAP26,TTBK2" Pubmed 2288909 Multiple genes encoding zinc finger domains are expressed in human T cells. Pubmed 9.27E-05 1.00E+00 1.20E-02 1.55E-01 11 31 "ZNF44,ZFP1,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZNF45,ZNF30" Pubmed 22889265 Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons. Pubmed 9.27E-05 1.00E+00 1.20E-02 1.55E-01 11 31 "CALB1,FGFR3,GAD1,GFAP,GLI2,MAPT,NKX2-2,CLDN11,PTCH1,SYN1,SLC17A6" Pubmed 7542761 Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Pubmed 9.27E-05 1.00E+00 1.20E-02 1.55E-01 11 31 "CSF1R,FGFR1,GABRA2,GABRB1,JAK1,JAK2,KIT,DDR2,PDGFRA,TEK,TIE1" Pubmed 25179941 Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Pubmed 9.27E-05 1.00E+00 1.20E-02 1.55E-01 11 31 "ASCL1,CALB1,OLIG2,GAD2,GFAP,GLUL,NKX2-2,PAX6,RXRG,SLC6A9,SOX1" Pubmed 25391964 Radial glia require PDGFD-PDGFR? signalling in human but not mouse neocortex. Pubmed 9.27E-05 1.00E+00 1.20E-02 1.55E-01 11 31 "BMP7,C5,PRC1,QKI,LRRC17,FABP7,PAX6,SOX1,SOX2,STOX1,RFTN2" Pubmed 20301532 Charcot-Marie-Tooth Hereditary Neuropathy Overview Pubmed 9.65E-05 1.00E+00 1.20E-02 1.55E-01 14 47 "CNTNAP1,PRX,MTMR2,AIFM1,DNM2,DRP2,BSCL2,DCTN2,GJB1,PMP22,SH3TC2,SBF1,KIF1B,FGD4" Pubmed 8631898 Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MAP2,MAP4,MAPT,MARK1" Pubmed 8955346 The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "APBA2,APBB1,APBB2,APP" Pubmed 9750131 Dot far-western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EFS,PTK2B,FYN,PTK2" Pubmed 19240035 {beta}-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "APP,CAMK2A,GRIA1,GRIN1" Pubmed 18794346 Tuberous sclerosis complex proteins control axon formation. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BRSK2,BRSK1,TSC1,TSC2" Pubmed 20573900 "Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ASTN1,GFAP,NLGN1,ASTN2" Pubmed 18760366 Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTNAP2,KCNA1,KCNA2,CNTN2" Pubmed 25653382 Axon initial segment-associated microglia. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ANK3,VCAN,CX3CR1,BCAN" Pubmed 15693750 Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SPAG9,MAPK8,MAPK9,MAPK10" Pubmed 25644714 Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,CAMK2B,RASGRF1,VLDLR" Pubmed 21940441 IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase ?. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BSN,SHANK1,IL1RAPL1,LRRC4B" Pubmed 9314494 High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DLGAP2,ARHGEF10,KBTBD11,FAM13A" Pubmed 20858756 ?-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SNCAIP,KCNJ11,SNCA,ABCC8" Pubmed 14960623 Multiple roles for slits in the control of cell migration in the rostral migratory stream. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,ROBO2,SLIT1,ROBO3" Pubmed 24314728 "Fezf2 expression identifies a multipotent progenitor for neocortical projection neurons, astrocytes, and oligodendrocytes." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GAD1,MAPT,FEZF2,CUX2" Pubmed 24381170 Clusterin is a ligand for apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and signals via the Reelin-signaling pathway. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CLU,RELN,VLDLR,LRP8" Pubmed 19657020 Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CACNA1G,CACNA1E,GRIA1,GRM1" Pubmed 10662501 Structural and functional evolution of the L1 family: are four adhesion molecules better than one? Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CHL1,L1CAM,NRCAM,NFASC" Pubmed 24096136 Gephyrin plays a key role in BDNF-dependent regulation of amygdala surface GABAARs. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GPHN,GABRA1,GABRG1,GABRG2" Pubmed 9895385 Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EDN3,EDNRB,RET,UCHL1" Pubmed 14654075 Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CSF1,CSF1R,KIT,KITLG" Pubmed 15707673 "Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "L1CAM,NCAM1,CNTN2,CADM1" Pubmed 20301604 X-Linked Adrenal Hypoplasia Congenita Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NR0B1,DMD,GK,IL1RAPL1" Pubmed 8806824 Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DCT,KIT,KITLG,PDGFRA" Pubmed 15485773 "Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and biochemical study." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "FYN,MAG,MBP,NCAM1" Pubmed 23360469 Genetic testing in benign familial epilepsies of the first year of life: clinical and diagnostic significance. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KCNQ2,KCNQ3,PRRT2,SCN2A" Pubmed 19830834 Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB1,GFAP,PADI2,MAP2" Pubmed 19722700 Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CLTC,DNM1,DYRK1A,SH3GL2" Pubmed 17367784 Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 26518133 "The ?1, ?2, ?3, and ?2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GABRA1,GABRA2,GABRA3,GABRG2" Pubmed 11027579 "The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "HAPLN1,NCAN,HAPLN2,BCAN" Pubmed 11804778 Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NTNG2,L1CAM,NTNG1,CNTN2" Pubmed 10468580 Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,CACNA1D,STX1B,STX1A" Pubmed 20849899 Role of TPPP/p25 on ?-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SNCAIP,TPPP,SIRT2,SNCA" Pubmed 18201104 Different conformational switches underlie the calmodulin-dependent modulation of calcium pumps and channels. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP2B1,CALM1,MYLK2,RYR1" Pubmed 15834631 "Cardiac muscle cell cytoskeletal protein 4.1: analysis of transcripts and subcellular location--relevance to membrane integrity, microstructure, and possible role in heart failure." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EPB41,EPB41L1,EPB41L2,EPB41L3" Pubmed 25080596 Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GABRA1,GABRA2,GABRA3,GABRG2" Pubmed 19570895 Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,ATP1A2,FXYD1,SLC12A2" Pubmed 11472852 Expression patterns of Slit and Robo family members during vertebrate limb development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ROBO1,ROBO2,SLIT1,ROBO3" Pubmed 20489179 Strong synaptic transmission impact by copy number variations in schizophrenia. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DOC2A,CACNA1B,RET,RIT2" Pubmed 26410934 [The Role of Neurotrophins and Neurexins Genes in the Risk of Paranoid Schizophrenia in Russians and Tatars]. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NRXN1,NTRK2,NTRK3,NXPH1" Pubmed 18506028 "C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB2,RAPGEF1,MAP2,RELN" Pubmed 24899703 Cortical interneurons require Jnk1 to enter and navigate the developing cerebral cortex. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB1,MAPK8,MAPK9,MAPK10" Pubmed 11714752 Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "PPP3CA,PPP3CB,PPP3CC,CABIN1" Pubmed 20452978 Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "RIMS4,RIMS2,RIMS3,RIMS1" Pubmed 25865415 Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GABRA1,GABRA2,GABRA3,GABRA5" Pubmed 19380828 HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "PDPK1,MAPK8,MAPK9,MAPK10" Pubmed 12954862 Distribution of kainate receptor subunits at hippocampal mossy fiber synapses. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GRIK2,GRIK3,GRIK4,GRIK5" Pubmed 19833108 Regional distribution of the leucine-rich glioma inactivated (LGI) gene family transcripts in the adult mouse brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "LGI1,LGI2,LGI3,LGI4" Pubmed 23913827 "SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GRM1,KIT,MITF,SOX10" Pubmed 27770832 Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 17234593 "Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,ATP1A2,ATP1A3,GRIN1" Pubmed 1374350 Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CSF1,CSF1R,KIT,KITLG" Pubmed 11401406 Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DCT,EDN3,KITLG,NF1" Pubmed 15705853 Mammalian SAD kinases are required for neuronal polarization. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BRSK2,TBR1,BRSK1,CNTN2" Pubmed 11839681 Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "PDE3B,PDE4A,PDE4B,PDE4D" Pubmed 24790209 "Acetylcholine controls GABA-, glutamate-, and glycine-dependent giant depolarizing potentials that govern spontaneous motoneuron activity at the onset of synaptogenesis in the mouse embryonic spinal cord." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC32A1,SYP,SLC17A7,SLC17A6" Pubmed 16226035 Evidence for the existence of two Robo3 isoforms with divergent biochemical properties. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,ROBO1,ROBO2,ROBO3" Pubmed 16525039 A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ANK3,KCNA2,KCNQ2,KCNQ3" Pubmed 10471813 A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MAPK8,MAPK9,MAPK10,MAPKBP1" Pubmed 17320079 Thrombospondin-4 and matrix three-dimensionality in axon outgrowth and adhesion in the developing retina. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB1,TUBB3,GFAP,THBS4" Pubmed 18821008 GABA(A) receptor downregulation in brains of subjects with autism. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GABRA1,GABRA2,GABRA3,GABRB3" Pubmed 24469251 Miswiring the brain: ?9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNR1,STMN2,L1CAM,MAPK8" Pubmed 24243019 Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ASCL1,MAPT,POU3F2,MYT1L" Pubmed 24423059 New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "OLIG1,OLIG2,MBP,PLP1" Pubmed 27537483 Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ERC2,RIMS2,RIMS1,ERC1" Pubmed 10719889 Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "OLIG1,OLIG2,PDGFRA,SOX10" Pubmed 18444965 Timeline and distribution of melanocyte precursors in the mouse heart. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DCT,EDN3,EDNRB,KIT" Pubmed 7568881 Molecular genetic analyses of myelin deficiency and cerebellar ataxia. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MAG,MBP,PLP1,PMP22" Pubmed 23022470 Alterations in the expression of PSA-NCAM and synaptic proteins in the dorsolateral prefrontal cortex of psychiatric disorder patients. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GAD1,NCAM1,SYP,SLC17A7" Pubmed 20525557 "JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ABCB1,MAPK8,MAPK9,MAPK10" Pubmed 15557343 Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "PPP3CB,SLC8A2,SLC8A1,SLC8A3" Pubmed 18331873 Distinct immunohistochemically defined areas in the medial amygdala in the developing and adult mouse. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB1,CALB2,NOS1,SLC17A6" Pubmed 23224879 Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1). Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,ATP1A2,FXYD1,SLC8A1" Pubmed 12942088 CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AP2A1,NUMB,DPYSL2,L1CAM" Pubmed 6194264 "Myelin basic protein deposition in the optic and sciatic nerves of dysmyelinating mutants quaking, jimpy, Trembler, mld, and shiverer during development." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "QKI,MBP,PLP1,PMP22" Pubmed 23644063 The role of SOX10 during enteric nervous system development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "FABP7,SOX2,SOX10,UCHL1" Pubmed 599283 "Myelin deficient, a new neurological mutant in the mouse." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CACNA2D2,QKI,MBP,PLP1" Pubmed 21883219 Reduced levels of the tyrosine phosphatase STEP block ? amyloid-mediated GluA1/GluA2 receptor internalization. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "APP,GRIA1,GRIA2,PTPN5" Pubmed 10381553 Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 23675446 Notch signaling maintains neural rosette polarity. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "PROM1,RBPJ,PRKCZ,TJP1" Pubmed 21217699 Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KAT8,MSL3,MSL1,KANSL1" Pubmed 17018285 Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NCOR1,DLG4,ERBB4,TAB2" Pubmed 17651422 Cajal-Retzius cells and subplate neurons differentially express vesicular glutamate transporters 1 and 2 during development of mouse cortex. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MAP2,RELN,SLC17A7,SLC17A6" Pubmed 15120852 Altered blood-brain barrier development in dystrophic MDX mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AQP4,DMD,GFAP,TJP1" Pubmed 23986251 Synaptic protein ?1-takusan mitigates amyloid-?-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "APP,DLG4,MAPT,SYP" Pubmed 12620390 Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "RIMS4,RIMS2,RIMS3,RIMS1" Pubmed 10336464 Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AP2A1,CLTC,DNM1,EPN2" Pubmed 27626661 SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAST,ERC2,BRSK1,ERC1" Pubmed 10624965 "Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KCNAB2,CNTNAP2,KCNA1,KCNA2" Pubmed 10428811 A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ARHGEF7,ARHGEF6,GIT2,GIT1" Pubmed 21190592 The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC32A1,GAD1,GAD2,SYP" Pubmed 17690840 Expression of oligodendroglial differentiation markers in pilocytic astrocytomas identifies two clinical subsets and shows a significant correlation with proliferation index and progression free survival. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "OLIG1,OLIG2,MBP,PDGFRA" Pubmed 14595443 The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "LRRC4C,NYAP1,NTNG1,LRRC4" Pubmed 17182677 Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KAT8,KAT7,KAT6B,KAT6A" Pubmed 18940311 Recurrent CNVs disrupt three candidate genes in schizophrenia patients. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NRXN1,CTNND2,MYT1L,ASTN2" Pubmed 26351028 Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,ATP2B3,CACNA1D,KCNJ5" Pubmed 22250198 "Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ADCY5,P2RY13,P2RX7,P2RY1" Pubmed 19131325 "Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CCK,CHGB,PDYN,SST" Pubmed 29084334 "Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ZNF385A,PSD2,PADI2,A2ML1" Pubmed 7706555 "Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "L1CAM,NCAM1,NRCAM,NFASC" Pubmed 26277340 "The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GRIK1,GRIK2,NETO2,NETO1" Pubmed 16407245 "Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP2A2,SLC24A2,SLC8A2,SLC8A1" Pubmed 21124317 Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NBAT1,BARD1,LMO1,CASC15" Pubmed 18854160 A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CDC42BPA,LURAP1,CDC42BPB,MYO18A" Pubmed 25851601 The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DOCK11,PAK3,DOCK10,DOCK9" Pubmed 24722207 Overexpression of LARGE suppresses muscle regeneration via down-regulation of insulin-like growth factor 1 and aggravates muscular dystrophy in mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "LARGE1,FKTN,IGF1,LAMA2" Pubmed 25369766 A systematic nomenclature for mammalian tropomyosin isoforms. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "TPM1,TPM2,TPM3,TPM4" Pubmed 25077544 JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BID,ALDH1L1,MAPK8,MAPK9" Pubmed 14593108 Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ANK2,SLC8A1,SPTAN1,SPTB" Pubmed 24076135 Developmental expression of IL-33 in the mouse brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "IL33,OLIG2,GFAP,MAP2" Pubmed 23044470 Distinct development of GABA system in the ventral and dorsal horns in the embryonic mouse spinal cord. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC12A5,SLC32A1,GAD1,GAD2" Pubmed 12700166 Spontaneous deletion of epilepsy gene orthologs in a mutant mouse with a low electroconvulsive threshold. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CHRNA4,KCNQ2,NKAIN4,ARFGAP1" Pubmed 17823315 A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC32A1,NLGN3,SYP,SLC17A7" Pubmed 10366625 "Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout mice." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GFAP,L1CAM,MAP2,MBP" Pubmed 28484035 Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "RELN,ITSN1,VLDLR,LRP8" Pubmed 9314527 Nef-mediated clathrin-coated pit formation. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AP1M1,CLTA,CLTB,CLTC" Pubmed 12441294 Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "FGFR3,GFAP,GLUL,PDGFRA" Pubmed 16179923 Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BMPR1B,DGKB,SOX5,SMOC1" Pubmed 8886980 N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "TMOD2,TMOD1,TPM1,TPM3" Pubmed 10066790 "AP-4, a novel protein complex related to clathrin adaptors." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AP4M1,AP4B1,AP4S1,AP4E1" Pubmed 14715953 Gephyrin is critical for glycine receptor clustering but not for the formation of functional GABAergic synapses in hippocampal neurons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GPHN,GABRA1,GABRA2,GABRG2" Pubmed 22785238 Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2?. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "INSM2,INSM1,PTPRN,PTPRN2" Pubmed 8786425 CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CASK,NRXN3,NRXN1,NRXN2" Pubmed 21169560 Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CLTC,DNM1,DNM2,TNK2" Pubmed 7509919 "The ligand-receptor interactions of the endothelin systems are mediated by distinct ""message"" and ""address"" domains." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 3418751 Expression of myelin protein genes in quaking mouse brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "QKI,MAG,MBP,PLP1" Pubmed 22411787 Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EFNB3,MAG,OMG,RTN4" Pubmed 11306627 Cortical axon guidance by the glial wedge during the development of the corpus callosum. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,GFAP,ROBO1,ROBO2" Pubmed 25411505 Netrin-G/NGL complexes encode functional synaptic diversification. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "LRRC4C,NTNG2,NTNG1,LRRC4" Pubmed 15662035 Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KCNAB2,KCND2,KCND3,KCNAB1" Pubmed 15454437 Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DPP10,DPP6,KCND1,KCND2" Pubmed 17369816 R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CACNA1E,KCNJ11,SST,ABCC8" Pubmed 9811881 Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DPP6,EN2,KIT,PDGFRA" Pubmed 25894826 Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 8663089 Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ADD1,CALM1,SPTAN1,SPTB" Pubmed 12542678 Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTNAP2,EPB41,NPPA,EPB41L3" Pubmed 9506712 Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1). Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KCNJ3,KCNK1,KCNK2,KCNK3" Pubmed 22403409 The protein phosphatase PP2A/B? binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "FYN,MAP2,MAPT,PTPA" Pubmed 15895369 "Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ZIC4,ZIC1,ZIC2,ZIC3" Pubmed 9619499 Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GRIA1,GRIA2,GRIK1,GRM5" Pubmed 20466094 Tuba8 is expressed at low levels in the developing mouse and human brain. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "TUBB3,TUBA8,TUBB2B,TUBA1A" Pubmed 10931822 The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AP1B1,AMPH,DNM1,CABIN1" Pubmed 17446412 Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Pubmed 18776950 M6a is expressed in the murine neural retina and regulates neurite extension. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "TUBB3,GLUL,GPM6A,SYP" Pubmed 10676964 Modulation of A-type potassium channels by a family of calcium sensors. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "KCND2,KCNIP3,KCNIP2,KCNIP1" Pubmed 19150847 "Draxin, a repulsive guidance protein for spinal cord and forebrain commissures." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GFAP,L1CAM,DRAXIN,CNTN2" Pubmed 18057022 Differential targeting of nNOS and AQP4 to dystrophin-deficient sarcolemma by membrane-directed alpha-dystrobrevin. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "AQP4,DMD,DTNA,NOS1" Pubmed 16077734 Analysis of four neuroligin genes as candidates for autism. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NLGN4X,NLGN3,NLGN4Y,NLGN1" Pubmed 18986510 Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ROBO1,ROBO2,ROBO3,CNTN2" Pubmed 21046454 Immunohistochemical and biochemical studies with region-specific antibodies to chromogranins A and B and secretogranins II and III in neuroendocrine tumors. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CHGA,CHGB,SCG3,SCG2" Pubmed 15175395 Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CACNA1G,CACNA1A,CACNB4,CACNG2" Pubmed 21632923 The cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTNAP1,CNTNAP2,EPB41L3,TMEM163" Pubmed 11889801 "[Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions]." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 25051234 Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BIN1,CLU,FGF14,MAPT" Pubmed 21946559 Structural basis for cell surface patterning through NetrinG-NGL interactions. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "LRRC4C,NTNG2,NTNG1,LRRC4" Pubmed 11030619 Combinatorial roles of the nuclear receptor corepressor in transcription and development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NCOR1,NCOR2,GFAP,MAP2" Pubmed 25666757 Whole-exome sequencing points to considerable genetic heterogeneity of cerebral palsy. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CD99L2,TENM1,L1CAM,PAK3" Pubmed 11106729 Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SPAG9,KLC1,MAPK8IP3,KLC2" Pubmed 1373175 Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "QKI,MOG,OMG,PLP1" Pubmed 14722083 "Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 12139915 Analysis of interactions of the adhesion molecule TAG-1 and its domains with other immunoglobulin superfamily members. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTN1,L1CAM,NRCAM,CNTN2" Pubmed 18620027 Clusterin expression during fetal and postnatal CNS development in mouse. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CLU,GFAP,MBP,SYP" Pubmed 19369569 Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GRIK1,GRIK2,GRIK3,GRIK5" Pubmed 7537231 Lethality of Rw/Rw mouse embryos during early postimplantation development. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "EN2,HTR5A,KIT,PDGFRA" Pubmed 17525706 Association of single nucleotide polymorphisms in endothelin family genes with the progression of atherosclerosis in patients with essential hypertension. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ECE2,EDN1,EDNRA,EDNRB" Pubmed 11967891 "Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MPDZ,TBR1,GBX2,PAX6" Pubmed 12815063 Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "FGF1,FGF12,FGF14,FGFR3" Pubmed 11543611 Analysis of SOX10 function in neural crest-derived melanocyte development: SOX10-dependent transcriptional control of dopachrome tautomerase. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DCT,KIT,MITF,SOX10" Pubmed 25875008 OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ERBB2,MAP2,NCAM2,SOX2" Pubmed 19217926 "Aspects of the neuroendocrine cerebellum: expression of secretogranin II, chromogranin A and chromogranin B in mouse cerebellar unipolar brush cells." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CALB2,GRIA1,MAP2,SCG2" Pubmed 20410110 Cotrafficking of SV2 and synaptotagmin at the synapse. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SV2B,SV2A,SYP,SYT1" Pubmed 23818941 Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CRLF1,IL6ST,JAK1,JAK2" Pubmed 27182061 "Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ARHGEF7,ARHGEF6,GIT2,GIT1" Pubmed 21149567 Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DNM1L,FIS1,OPA1,MFF" Pubmed 22423107 Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC12A6,GAD1,GAP43,GFAP" Pubmed 16324103 Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "NCAN,L1CAM,RELN,CNTN2" Pubmed 11724816 "Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ANK3,CALB1,NRCAM,NFASC" Pubmed 21037240 Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ANK3,NRGN,PBRM1,TCF4" Pubmed 27895162 Cannabinoid Receptor Interacting Protein 1a Competition with ?-Arrestin for CB1 Receptor Binding Sites. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ARRB1,ARRB2,CNR1,CNRIP1" Pubmed 7931345 "A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "RYR1,ZIC1,ZIC2,ZIC3" Pubmed 29737974 Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca2+-Activated K+ Current in Patients with Chronic Atrial Fibrillation. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CAMK2A,KCNN1,KCNN2,KCNN3" Pubmed 28691197 Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DCC,L1CAM,ROBO3,CNTN2" Pubmed 19900187 "beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ADD1,ADD2,ADD3,FYN" Pubmed 28054918 APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLC12A5,APP,GABRA1,GAD1" Pubmed 23083737 Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 8743987 The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CACNB4,IGF1,KITLG,TMPO" Pubmed 15188439 Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "GAP43,L1CAM,FEZF2,CNTN2" Pubmed 19109503 Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTNAP2,DLG2,DLG4,CNTN2" Pubmed 22975310 The microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretion. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "MSI1,PROX1,SYBU,SOX1" Pubmed 19564905 Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "ABI1,EPS8,BAIAP2,MAPK3" Pubmed 16104378 Gene expression differences in mice divergently selected for methamphetamine sensitivity. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CSNK1E,PPP1R1B,GRIA1,MED1" Pubmed 22311982 Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "DPP10,DPP6,KCND2,KCNIP3" Pubmed 15143189 "Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels." Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "WASF1,ABI1,ABI2,STX1A" Pubmed 23821748 Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "STX1B,SNAP25,STX1A,STXBP1" Pubmed 20133774 The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "CNTN1,CNTN3,PTPRG,PTPRZ1" Pubmed 11384986 Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase. Pubmed 9.82E-05 1.00E+00 1.20E-02 1.55E-01 4 4 "BIN1,MAP4K3,SH3GLB1,SH3GL2" Pubmed 26777405 ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Pubmed 9.83E-05 1.00E+00 1.20E-02 1.55E-01 52 315 "ADAR,ANXA7,DST,MAP4K4,CNN3,MAGED1,SEC24C,SIPA1L1,CTNND1,PUM1,G3BP2,DPYSL2,PDCD6IP,SUGP2,EIF4G1,EIF4G2,ELAVL2,TUBB3,PRMT5,FHL1,SYNCRIP,SORBS1,PDLIM5,KHDRBS3,CELF1,STAU2,ZNF638,CBX1,TUBA1C,CIT,ATXN2L,HSP90AA1,MAP4,MOV10,MYO6,TNPO2,RNH1,ZC3H14,ATXN2,DHX30,PALLD,RBM26,LARP4,STAU1,PRRC2C,TCEA1,PUM2,TPM1,TPM2,CSDE1,HNRNPA3,FXR1" Pubmed 19490893 A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Pubmed 1.00E-04 1.00E+00 1.22E-02 1.58E-01 54 331 "ADCY8,MPDZ,PROM1,NAE1,CA12,USP6,CDC27,CACNA2D2,ADGRG1,CHN1,RCHY1,FEZ2,TOMM20,COPS4,DCTN4,CDKL3,FCGR1A,NOP56,WDR83,ZMAT1,TUBGCP4,FREM1,COPS8,DCLK2,DIDO1,JAK1,MATN2,MID1,ADAM22,NEK1,NF1,SLC11A2,EXOSC10,RELN,SYTL2,GON4L,RFX4,FBXW7,EMID1,CCDC112,FRMPD1,WDR37,RIMS1,SNRPN,ZC3H13,FNDC9,WWC1,TK2,UBTF,FLRT2,XPO1,NAV3,UBE3B,FBXO36" Pubmed 21909110 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Pubmed 1.10E-04 1.00E+00 1.34E-02 1.73E-01 13 42 "ATP2B1,CACNB2,SLC4A7,EBF1,EDN3,GNAS,GUCY1A1,GUCY1B1,MAP4,MOV10,FIGN,ATXN2,CABCOCO1" Pubmed 26365490 Systematic identification of factors for provirus silencing in embryonic stem cells. Pubmed 1.10E-04 1.00E+00 1.34E-02 1.73E-01 30 151 "SDE2,ARID1A,MTA3,AIFM1,TJP2,AKAP12,SEC24C,DAPK1,COPS4,SEC23B,RGPD5,NCKAP1,COPS8,CBX1,EML4,KAT7,RCOR2,NRDC,RTN1,SMARCA4,CAND2,PRRC2C,DNAJC9,ANKRD28,TBL1X,SIRT1,CBX5,TP53BP1,SMARCAD1,LAS1L" Pubmed 22379092 "A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening." Pubmed 1.10E-04 1.00E+00 1.34E-02 1.74E-01 17 65 "SRSF11,CREM,REEP2,FHL1,NUDT21,HMGB1,HNRNPK,TCEAL6,RBPJ,PTPA,PPP2R5E,PPP5C,RAD51D,CCDC25,SMARCC2,RELL2,ZBTB38" Pubmed 20424473 L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. Pubmed 1.11E-04 1.00E+00 1.35E-02 1.74E-01 29 144 "LTBP4,BMP7,CACNA1D,CACNA1E,CCK,ADGRG1,EGFR,CALCRL,FGF1,FOLR2,GFRA1,GPR37,GRK4,KCNJ4,KCNMA1,P2RX7,PDGFRA,PTH1R,RYR1,RYR3,SLC1A6,SLC1A7,SLC6A7,SLC6A11,SLC8A1,SLC11A1,SLC14A1,SLC15A2,TGFBR3" Pubmed 25157170 Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "CALB1,EIF4G1,EIF5,FOXG1,GFAP,L1CAM,MAP2,PAX6,SATB2" Pubmed 12812986 "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation." Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "ACTN2,CEP126,SPTBN4,DISC1,MYH7,ANKHD1,ITSN1,ATF7IP,SYNE1" Pubmed 20808958 Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "ASCL1,CALB2,LHX2,TUBB3,GFAP,HES5,NEUROD1,PROX1,SOX2" Pubmed 11124115 Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "ASCL1,LHX2,DLX1,ETV1,TBR1,GAD1,PAX6,POU3F4,TAC1" Pubmed 23826228 Systematic Analysis of the Functions of Lysine Acetylation in the Regulation of Tat Activity. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "TUBD1,TUBA1B,TUBB3,TUBB4A,TUBA8,TUBB2B,TUBB2A,TUBB1,TUBA1A" Pubmed 21348951 Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "CA8,FGF1,NRG3,GRIK2,FAM19A2,HTR2A,BTBD3,SNAP25,UBE3A" Pubmed 19887680 The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "LHX2,NKX2-2,PAX6,PTCH1,RFX2,RFX3,RFX4,TACR1,CNTN2" Pubmed 20301725 Hypertrophic Cardiomyopathy Overview Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "ACTN2,B3GAT3,PRKAG2,MYOZ2,MYLK2,MYH6,MYH7,MYL3,TPM1" Pubmed 18628988 Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease. Pubmed 1.14E-04 1.00E+00 1.37E-02 1.78E-01 9 22 "CDC42,DCC,PLXNC1,EPHB1,FYN,PPP3CA,MRAS,NTNG1,PAK5" Pubmed 22566634 The genetic architecture of economic and political preferences. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 12 37 "CADPS,DLGAP1,AKAP6,RGS6,PLXNA4,RAB30,CNTN3,PDE4B,ASTN2,DCBLD1,EML6,NETO1" Pubmed 18267097 Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 12 37 "VCAN,ERBB2,ADAMTS8,HAS2,MEF2C,MEST,NPPA,SMARCA4,TEK,TIE1,HEY1,ADAMTS9" Pubmed 18270576 Individual retinal progenitor cells display extensive heterogeneity of gene expression. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 12 37 "LHX2,CRYM,MAML1,FOXM1,FOXO3,GLUL,PTCH1,RLBP1,RXRA,HES6,RHBDL3,TCF7L2" Pubmed 26297811 Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 12 37 "GAS7,NRP2,C1QL2,KIF26A,GBX2,GFRA2,PIK3R1,IRX1,ROBO3,TAL1,CNTN2,CUX2" Pubmed 23592779 "Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head." Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 12 37 "FGF17,BMP7,NOG,EDIL3,EMX2,EN2,FGFR1,FGFR3,FOXG1,SMAD1,SMAD9,MAPK3" Pubmed 18298960 "CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA." Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "ZIC4,GLI2,ZIC5,ZIC1,ZIC2,ZIC3" Pubmed 27810937 Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CPEB2,TUBB3,NEFH,CPEB3,CPEB4,TACR1" Pubmed 17581864 HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "AP2A1,AP2A2,AP1M1,CLTA,CLTB,CLTC" Pubmed 18054859 Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "PPFIA2,PPFIA1,CASK,CDK5R1,CACNA1B,SYP" Pubmed 12756228 JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "PAX6,MAPK8,MAPK9,MAPK10,PTCH1,SOX2" Pubmed 7791877 Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "AP2A1,SYT6,STX2,SYT3,STX1A,SYT1" Pubmed 23934215 Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "GNAO1,MYO6,GPSM2,PRKCZ,PARD3,VANGL2" Pubmed 19298847 In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain: implication of ErbB receptors for dopaminergic neurons. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "EGFR,OLIG2,ENO2,ERBB2,ERBB4,S100B" Pubmed 20950796 Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "HAPLN1,NCAN,B3GAT1,HAPLN2,BCAN,TNR" Pubmed 23147502 Dystroglycan on radial glia end feet is required for pial basement membrane integrity and columnar organization of the developing cerebral cortex. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "ETV1,TBR1,GFAP,PAX6,RELN,RORB" Pubmed 24501358 RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "ASCL1,OLIG2,ETV1,TUBB3,GFAP,MAPK3" Pubmed 19515974 Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "APC,OLIG1,OLIG2,PDGFRA,PLP1,TCF7L2" Pubmed 19622544 Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "ACTN2,CDH2,MEF2C,NPPA,MAPK8,MAPK9" Pubmed 15681609 Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "NCOA1,NCOR1,NCOR2,PPARGC1A,MED1,RXRA" Pubmed 15820695 CAPS1 regulates catecholamine loading of large dense-core vesicles. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CADPS,CHGA,STX1A,STXBP1,SYT1,SCG2" Pubmed 22228756 Sall1 regulates cortical neurogenesis and laminar fate specification in mice: implications for neural abnormalities in Townes-Brocks syndrome. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "TUBB3,TBR1,PAX6,POU3F2,RELN,SALL1" Pubmed 11953448 Interaction between metabotropic glutamate receptor 7 and alpha tubulin. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALM1,TUBA1B,TUBA8,GRM5,GRM7,TUBA1A" Pubmed 21228158 A role for FE65 in controlling GnRH-1 neurogenesis. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "APBB1,APP,ELAVL3,ELAVL4,PRPH,SOX2" Pubmed 16957075 Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALB2,TUBB3,GRIA1,GRM2,PAX6,RELN" Pubmed 28344083 Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "PTCH2,OLIG2,GLI2,NKX2-2,PTCH1,HHIP" Pubmed 22046273 "Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits." Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CSF1,CSF1R,GFAP,MBP,S100B,RTN4" Pubmed 27680501 Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "SMAD1,SMAD9,MBP,PPM1L,MAPK3,MAPK8" Pubmed 23175820 The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "LDB2,CNR1,TBR1,L1CAM,PRKCG,SATB2" Pubmed 17568776 Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALM1,CAMK2A,CAMK2G,KRIT1,RCHY1,UBC" Pubmed 19332541 N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CAMK2A,CAMK2B,GRIN3A,GRIN1,GRIN2C,GRIN2D" Pubmed 26755700 The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "NUMB,GPSM1,GNAO1,PAX6,GPSM2,TJP1" Pubmed 17038521 Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "SV2B,SV2A,ETV1,TBR1,NTRK2,PAX6" Pubmed 28929580 Selective expression of eGFP in mouse perivascular astrocytes by modification of the Mlc1 gene using T2A-based ribosome skipping. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "AQP4,CALB1,TUBB3,GFAP,MBP,MLC1" Pubmed 19233709 Expression QTL and regulatory network analysis of microtubule-associated protein tau gene. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "TAOK1,APBB2,MAPT,ATXN7,SLC1A3,SYN2" Pubmed 11152634 Distinct cortical migrations from the medial and lateral ganglionic eminences. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALB1,DLX1,TUBB3,NOS1,NPY,SST" Pubmed 15880651 Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "OLIG2,MBP,NKX2-2,PDGFRA,PLP1,SOX10" Pubmed 29784671 A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CELSR3,MYO7A,NEFH,SOX2,FZD3,VANGL2" Pubmed 12508235 Targeted disruption of mouse Dach1 results in postnatal lethality. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "DACH2,GFAP,MSI1,SLC1A3,SST,TRH" Pubmed 16950124 Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "OLIG2,GLI2,NKX2-2,PAX6,TCF4,TCF7L2" Pubmed 15920476 v-SNAREs control exocytosis of vesicles from priming to fusion. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "RAB3A,SNAP25,STX1A,VAMP1,SYP,SYT1" Pubmed 12777533 Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "MED12,AFF2,IL1RAPL1,L1CAM,OPHN1,PAK3" Pubmed 15781876 Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "BMPR1B,HAPLN1,SMAD1,SMAD9,SOX6,SOX5" Pubmed 23499385 Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "TUBB3,TBR1,NEUROD1,PAX6,SOX2,SATB2" Pubmed 29716946 Cell-autonomous role of GFR?1 in the development of olfactory bulb GABAergic interneurons. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALB1,CALB2,GAD1,GFAP,GFRA1,RELN" Pubmed 15728677 Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "COL9A1,COL9A2,COL9A3,NECTIN3,AFDN,TJP1" Pubmed 12642493 Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALB1,CALB2,SLIT2,GAD1,NPY,SLIT1" Pubmed 25199915 GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "FOXO3,GRIK2,RGS7,SOX6,LIMCH1,CADM2" Pubmed 23166838 Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "OLIG2,GLI2,NKX2-2,PAX6,PTCH1,KIF7" Pubmed 11739749 The septin CDCrel-1 is dispensable for normal development and neurotransmitter release. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CAMK2A,SEPT7,DLG4,SEPT4,SNAP25,STXBP1" Pubmed 16687575 The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "CALB1,CDH2,FYN,GAP43,NCAM1,MAPK8" Pubmed 16284117 Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Pubmed 1.22E-04 1.00E+00 1.44E-02 1.86E-01 6 10 "FGFR1,FGFR3,GLI2,PTCH1,PTHLH,PTH1R" Pubmed 21308776 DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. Pubmed 1.23E-04 1.00E+00 1.45E-02 1.88E-01 26 124 "ALCAM,SEMA7A,C1QC,MS4A7,CSF1R,CX3CR1,SIRPA,EDIL3,PLXNC1,BSCL2,SEMA4D,DKK3,PSRC1,LILRB4,NCKAP1L,IGF1,TM6SF1,MSR1,TREM2,PTX3,TAC1,ATP13A2,ZMAT3,TPD52,ZIC1,PLD4" Pubmed 23377640 Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. Pubmed 1.24E-04 1.00E+00 1.46E-02 1.89E-01 14 48 "CCNH,FEM1B,FGF12,AK8,IGFBP1,IL12A,KCTD15,EPN1,SCHIP1,RASGEF1B,ENOX1,ATXN1,CHST8,GALNT17" Pubmed 28579317 Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "CALB1,CALB2,LHX2,TUBB3,GLUL,MITF,PAX6,MAPK3,PROX1,SOX2" Pubmed 12654290 BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "BMPR1B,CALB2,SLIT2,VAX2,EFNA2,EFNB3,MAG,PAX6,SLC1A3,ZIC2" Pubmed 24148613 Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "ASCL1,LHX2,DLX1,OLIG1,OLIG2,HES5,NEUROD1,NHLH1,PAX6,HEY1" Pubmed 22323600 Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "CALB1,GAD1,RBPJ,HES5,NEUROD1,PAX6,RXRG,HES6,SLC6A9,HEY1" Pubmed 28077597 Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "USP28,LRRFIP1,ABCC9,RCAN2,FOXO3,MEF2C,MYO5A,MYO6,PAX6,MYO18A" Pubmed 23144326 Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Pubmed 1.28E-04 1.00E+00 1.50E-02 1.94E-01 10 27 "RNF150,NTM,EYA1,JAKMIP3,OPCML,P2RX7,HYDIN,ASRGL1,KAZN,WNT7A" Pubmed 25189868 Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study. Pubmed 1.29E-04 1.00E+00 1.51E-02 1.95E-01 11 32 "ADARB2,NRXN3,SACS,TRAPPC9,FRY,GRB10,LRP1B,MN1,OPCML,RPS6KA2,TNFRSF19" Pubmed 21074523 FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors. Pubmed 1.29E-04 1.00E+00 1.51E-02 1.95E-01 11 32 "ASCL1,PROM1,TJP2,ELAVL3,ELAVL4,FGFR1,FGFR3,MAPK3,SOX2,TJP1,PARD3" Pubmed 15340161 Signal peptide prediction based on analysis of experimentally verified cleavage sites. Pubmed 1.32E-04 1.00E+00 1.55E-02 2.00E-01 45 264 "NLGN4X,CADM3,AZGP1,CRLF1,ADGRG1,JAM2,LY86,CST3,SPOCK2,NTM,SIDT2,EFNB3,EGFR,PCOLCE2,CALCRL,EPHB1,FCGR1A,FCGRT,NPTN,SARAF,DKK3,TMEM25,NXPH3,VSIG4,SCRG1,ITGA7,LAMP2,NELL2,CYTL1,SERPINE2,DRAXIN,TNFRSF19,IL17RB,NTNG1,LRRC55,CNTN2,PCDHB10,TEK,TIE1,TLR4,TMEFF2,FLRT2,LYPD6,FZD3,NETO2" Pubmed 24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Pubmed 1.33E-04 1.00E+00 1.55E-02 2.00E-01 15 54 "ALCAM,PPT2,FADS2,SLC45A1,PPT2-EGFL8,CLVS1,CDK18,ELOVL2,RAB3IL1,SLC1A2,TLR4,CSMD1,RPL7L1,BEST1,JMJD1C" Pubmed 25631074 Analysis of HIV-1 Gag protein interactions via biotin ligase tagging. Pubmed 1.33E-04 1.00E+00 1.55E-02 2.00E-01 15 54 "ATP1A1,EIF4G1,EIF5,EPB41,EPB41L2,ATXN2L,MAP4,AFDN,HNRNPM,XRN1,RBM26,EPB41L3,PRRC2C,TMPO,CSDE1" Pubmed 21525035 PEX14 is required for microtubule-based peroxisome motility in human cells. Pubmed 1.33E-04 1.00E+00 1.55E-02 2.00E-01 15 54 "ARHGEF2,DCTN1,DNM2,DNM1L,TUBA1B,TUBB3,TUBB4A,IQGAP2,DHRS4,TUBB2B,PEX2,PEX5,TCP11L1,TUBB2A,TUBA1A" Pubmed 15790807 Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Pubmed 1.35E-04 1.00E+00 1.58E-02 2.05E-01 17 66 "BCL2L2,DNM2,SGK2,AIFM3,KCNH2,L1CAM,LSS,PLXNB3,RELN,CASTOR1,MORC4,DGLUCY,ARFGAP1,SSPO,SYNE2,MCF2L,CLIP2" Pubmed 19598235 "Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome." Pubmed 1.35E-04 1.00E+00 1.58E-02 2.05E-01 17 66 "ABAT,NLGN4X,CNR1,ARNT2,CALCRL,GABRB3,RAPGEF4,IGF1,MAOB,NRCAM,NTRK2,NTRK3,OXTR,SCP2,NLGN1,TAC1,VGF" Pubmed 23362303 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Pubmed 1.36E-04 1.00E+00 1.59E-02 2.05E-01 16 60 "NCKAP5,PPT2,FADS2,CNN3,SEC31B,PLXNA4,GPR61,PPT2-EGFL8,ZNF512,GRID1,GRIK2,KCNJ16,PTPRD,RAB3IL1,CAMTA1,FAM13C" Pubmed 17150988 Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "EMX2,EPHA5,FHL1,DKK3,HES5,NFIX,SMOC1,TCF4" Pubmed 12815626 Expression of Sox transcription factors in the developing mouse pancreas. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "SOX8,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15" Pubmed 11149944 Serological detection of cutaneous T-cell lymphoma-associated antigens. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "ZNF638,MIA2,TSPYL2,RBM26,FAM208A,PARD3,ZMYND8,UBE3A" Pubmed 11859196 Transcriptional regulation of cortical neuron migration by POU domain factors. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CDK5R1,CDK5R2,MAP2,POU3F2,RELN,RORB,VLDLR,LRP8" Pubmed 16968817 Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CALB1,OLIG1,OLIG2,GAD1,GAD2,PLP1,SLC6A1,SLC17A7" Pubmed 24157949 Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "DLX1,ERBB4,ETV1,GBX2,NPY,SOX6,ARX,SST" Pubmed 23818142 Splicing factor TRA2B is required for neural progenitor survival. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "NRP2,SRSF11,SUGP2,TBR1,PSIP1,FEZF2,TRA2B,SOX2" Pubmed 26449264 A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CALB1,CALB2,VAX2,DLX1,GFAP,NEFH,PAX6,TSC1" Pubmed 18430798 Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CALB1,CALB2,GAD1,NEFH,PENK,PRKCG,RET,TAC1" Pubmed 23056351 The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "TBR1,MAP2,PAX6,POU3F2,PROX1,RELN,SOX2,SATB2" Pubmed 23160044 BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "NUMB,MAML1,FABP7,TUBB3,TBR1,HES5,PAX6,SIRT1" Pubmed 24528677 Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "ASCL1,NRP2,ETV1,GBX2,PAX6,IRX1,PTCH1,ROBO3" Pubmed 23534349 Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "LDB2,MAGI1,MICAL2,DPP6,MFSD2A,SERPINI1,TMEM132D,NKAIN2" Pubmed 23616538 Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "ASCL1,GAD1,NPY,PDYN,PRPH,RORB,KCNIP2,SLC17A6" Pubmed 20148032 Rfx6 directs islet formation and insulin production in mice and humans. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CHGA,NKX2-2,RFX2,RFX3,RFX4,SST,SYP,IFT88" Pubmed 10393115 Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CALB1,CALB2,ETV1,TUBB3,GAD1,GNAL,MAP2,PAX6" Pubmed 21205797 Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "ASCL1,GAD1,GBX2,NKX2-2,NPY,SOX2,TAL1,SLC17A6" Pubmed 29158485 Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "CLTC,DNM2,FDFT1,HMGCR,LAMP2,MYO5A,RAB5B,EXOC7" Pubmed 19027001 Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "ASCL1,LHX2,EBF1,EYA1,GAP43,NEUROD1,PAX6,SOX2" Pubmed 12874134 Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Pubmed 1.37E-04 1.00E+00 1.59E-02 2.05E-01 8 18 "OLIG2,NKX6-2,NKX2-2,PAX6,PDGFRA,PRPH,DBX2,SOX10" Pubmed 29128334 A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-?B Signaling. Pubmed 1.39E-04 1.00E+00 1.60E-02 2.07E-01 108 787 "ACLY,ACTN1,ADAR,ADD1,KIDINS220,AP1B1,AK2,ANXA7,TNRC6C,API5,ARHGDIA,CCAR2,DYNLL1,ATP1A1,ATP2A2,ALDH7A1,KIF1A,BID,BLM,FUBP1,AP1M1,CALM1,CANX,INA,AIFM1,SEPT7,CDC42,CLTB,COX4I1,IST1,DGKG,DBN1,YTHDC1,HP1BP3,SEC16A,ACOT8,PDCD6IP,DNM1L,EEF1D,EIF4G1,COPS4,ATP5PD,NOP56,DCTN2,UFM1,ZNF512,MTHFD2,SEPT9,GART,GFAP,DHRS4,TTBK1,COPS8,RNPS1,SPIN1,CBX1,GOLGB1,NUDT21,GSN,HBA1,HPS5,ACOT7,HMGB1,IDH3A,STMN1,MAT2A,CCDC80,MYO6,NACA,NAP1L1,NDUFA5,NEFM,NUMA1,PCMT1,PCSK1,TMOD2,FAM98B,OLA1,PLEC,PPM1B,EPDR1,PRPH,PSMA6,PSMD13,MYH14,ELP2,ZC3H14,SAFB,SARS,SCP2,COPZ1,MYO18A,SHMT2,DHX30,SMARCE1,GANAB,DNAJC9,RALYL,TJP1,TMPO,TPD52,TPM1,TPM3,TPM4,AMOT,UCHL1,PITPNB,FIP1L1" Pubmed 21399614 Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Pubmed 1.43E-04 1.00E+00 1.61E-02 2.08E-01 29 146 "DYNLL1,PDE4DIP,KIAA0586,DCTN1,KIAA0753,CEP170,DCTN4,CEP85L,CEP78,DCTN2,TUBGCP4,CNTRL,LRRCC1,KIF2A,POC1B,NEK1,ODF2,PRKACB,CEP41,PPP2R3C,CEP97,CLIP1,CDK5RAP2,RAP1GAP2,CEP68,FBXW11,RPGRIP1L,CLASP1,CCDC14" Pubmed 26439863 Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef. Pubmed 1.43E-04 1.00E+00 1.61E-02 2.08E-01 27 132 "ELFN2,LRFN1,SCARB1,CD81,ARHGEF2,NRXN3,SLC4A7,NECTIN3,CSF1,GAPVD1,CD99L2,EIF4G1,CD320,FGFR1,SEMA4D,GART,ADGRA3,NCKAP1L,IPO5,PCDH9,NCR3LG1,RAP1GDS1,SEMA4A,PCDHGB1,VLDLR,TMEM237,SLC38A1" Pubmed 21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Pubmed 1.44E-04 1.00E+00 1.61E-02 2.08E-01 13 43 "ADCY8,SLC44A5,EDNRB,CLVS1,ARPP21,GFRA2,HMGB1,NME9,RNF219-AS1,NCAM1,PCSK5,KCNT2,FRMD6" Pubmed 18614579 Hedgehog signaling is involved in development of the neocortex. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "CALB2,CDH2,TUBB3,TBR1,MAP2,PAX6,RELN" Pubmed 22586713 Hmx1 is required for the normal development of somatosensory neurons in the geniculate ganglion. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "HMX1,NEFH,NTRK2,NTRK3,PRPH,RET,SOX10" Pubmed 21920314 Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "DLG2,DLG3,DLG4,DYNC1I1,TJAP1,PRKCZ,TJP1" Pubmed 17589506 Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "NUMB,PROM1,CDH2,NUMBL,GFAP,GRIN1,NEFH" Pubmed 14993235 "Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate." Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "FGFR3,PTCH1,PTHLH,PTH1R,SOX6,SOX5,SPP1" Pubmed 21325536 Wnt5a is a transcriptional target of Dlx homeogenes and promotes differentiation of interneuron progenitors in vitro and in vivo. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "FZD9,CALB1,CALB2,TUBB3,MAPK8,MAPK9,MAPK10" Pubmed 25757017 The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "TUBB3,FOXG1,GFAP,KAT7,NEUROD1,SOX2,KAT6A" Pubmed 25721514 Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "NRP2,DPYSL2,OLIG2,NKX2-2,PRKCZ,TJP1,SEMA3B" Pubmed 28939666 The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "ASCL1,TUBB3,TBR1,PAX6,SOX2,SATB2,SLC17A7" Pubmed 29317485 "Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation." Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "CALB1,FABP7,GFAP,L1CAM,SMAD1,SMAD9,PAX6" Pubmed 21552265 Complex interactions between genes controlling trafficking in primary cilia. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "OLIG2,GLI2,NKX2-2,PAX6,PTCH1,IFT122,IFT88" Pubmed 12810600 Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "GFRA1,GFRA2,NOS1,NPY,NTRK2,NTRK3,RET" Pubmed 16407399 Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "OLIG1,OLIG2,GFAP,MBP,NKX2-2,PAX6,PDGFRA" Pubmed 18160702 Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "TBR1,MEF2C,NEUROD1,NEUROD2,NHLH1,FEZF2,SLC17A6" Pubmed 12239168 gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12" Pubmed 15640798 Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Pubmed 28981838 An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "MIER1,KMT5B,DOT1L,BRD8,CBX1,ING3,KDM4C" Pubmed 21766338 Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "OLIG2,FABP7,PAX6,POU3F4,SOX1,SOX2,SOX3" Pubmed 21943598 A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "CALB2,CCK,DLX1,ETV1,GAD2,NOS1,SST" Pubmed 9921901 CCG repeats in cDNAs from human brain. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "HCN2,NRXN1,SLC32A1,HCN1,LRP12,FEZF2,CA10" Pubmed 25450229 The contribution of rare and common variants in 30 genes to risk nicotine dependence. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "ARRB2,NRXN3,NRXN1,NRXN2,GRIN3A,DNM1,NTRK2" Pubmed 15491607 Alternative splice variants encoding unstable protein domains exist in the human brain. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "ARHGEF7,NRXN2,PPP1R16B,MYO18A,MAPKBP1,NFASC,PHLDB1" Pubmed 18985738 Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "VAX2,GFAP,SMAD1,SMAD9,MITF,PAX6,PROX1" Pubmed 22069191 Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "ASCL1,MAML1,HEYL,HES5,MAP2,HEY1,HEY2" Pubmed 27476503 Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "CALB1,SV2A,DLG4,TBR1,GFAP,PAX6,SATB2" Pubmed 18443282 Modular patterning of structure and function of the striatum by retinoid receptor signaling. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "ASCL1,CALB1,EBF1,PPP1R1B,PDYN,PENK,RXRG" Pubmed 27701636 Loss of Axin2 Causes Ocular Defects During Mouse Eye Development. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "AXIN2,CALB1,MITF,PAX6,PROX1,TCF4,TCF7L2" Pubmed 9584121 Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "GCK,NKX2-2,PAX6,PCSK1,POU3F4,SST,SYP" Pubmed 17389516 Stage-specific association of apolipoprotein A-I and E in developing mouse retina. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "SCARB1,DLG4,GFAP,MAP2,RLBP1,VLDLR,LRP8" Pubmed 8921394 Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "SOX8,SOX6,SOX2,SOX5,SOX10,SOX11,SOX15" Pubmed 24962325 Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "LARGE1,ANKRD44,C2orf88,LSAMP,NCAM2,FAM81A,SLC6A9" Pubmed 26874185 Subtype-Specific Genes that Characterize Subpopulations of Callosal Projection Neurons in Mouse Identify Molecularly Homologous Populations in Macaque Cortex. Pubmed 1.47E-04 1.00E+00 1.61E-02 2.08E-01 7 14 "CHN2,NECTIN3,DKK3,GFRA2,PTN,FEZF2,LIMCH1" Pubmed 18660489 Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Pubmed 1.49E-04 1.00E+00 1.61E-02 2.08E-01 43 250 "ACADM,ACLY,ADD1,AGT,ABCD2,GPAM,APOC2,NCOA1,SCARB1,ARHGAP33,NCOR1,NCOR2,ABCG1,EDN1,EDNRA,EDNRB,FDFT1,SORBS1,PPARGC1A,GK,RAPGEF1,NR3C1,ELOVL5,HMGCR,LSS,MEF2C,MSR1,NPPA,PDPK1,PIK3R1,PLTP,PPARA,MED1,PPP3CA,MAPK3,ELOVL2,FBXW7,RXRA,RXRG,SLC8A1,SMARCA4,SPP1,SIRT1" Pubmed 20053908 Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "BOC,CDON,EPHB1,L1CAM,ZIC2" Pubmed 11745664 GABA influences the development of the ventromedial nucleus of the hypothalamus. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GABRA3,GABRA5,GABRB3,GABRG2,GAD1" Pubmed 27619418 Pore size matters for potassium channel conductance. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "KCNA1,KCNA2,KCNA4,KCNA6,KCNMA1" Pubmed 12756176 The glial sling is a migratory population of developing neurons. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB2,ERBB4,TUBB3,GFAP,ROBO1" Pubmed 15813942 Behavioural phenotypes of hypomorphic KCC2-deficient mice. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SLC12A5,CALB1,CALB2,SLC12A4,SYP" Pubmed 16378758 "Expression of coiled-coil protein 1, a novel gene downstream of FGF2, in the developing brain." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,TBR1,GAD1,GAD2,RELN" Pubmed 18214987 E protein dosage influences brain development more than family member identity. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,GFAP,NEUROD2,TCF4,TCF12" Pubmed 25605781 A transient wave of BMP signaling in the retina is necessary for Müller glial differentiation. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ASCL1,NOG,GLUL,SMAD1,RLBP1" Pubmed 21655271 Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SRGAP3,L1CAM,ROBO1,ROBO2,CNTN2" Pubmed 10527873 Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLGAP2,DLGAP1,DLGAP3,DLG4,SHANK2" Pubmed 15385965 Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "APLP1,APP,MAP2,RELN,SLC1A3" Pubmed 17884558 Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DCC,EPHB1,GAD2,L1CAM,CNTN2" Pubmed 21295525 N-?-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ARHGEF7,CDC42,ARHGEF6,GIT2,GIT1" Pubmed 19243221 Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLG2,DLG3,DLG4,GRIN1,NETO1" Pubmed 21765815 Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NRP2,CCK,NRN1,NELL2,TCF12" Pubmed 16101898 Developmental changes in GABA receptor subunit composition within the gonadotrophin-releasing hormone-1 neuronal system. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GABRA1,GABRA2,GABRA3,GABRB3,PRPH" Pubmed 28118374 "Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "TUBB3,NEFH,PROX1,PRPH,SOX2" Pubmed 10894496 Identification of two chromosomal loci determining glucose intolerance in a C57BL/6 mouse strain. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CHGB,KCNB1,PCSK1,PCSK2,PIK3R1" Pubmed 17581972 Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SLIT2,ROBO1,ROBO2,SLIT1,CNTN2" Pubmed 16828986 "Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "LRFN2,LRFN1,DLG4,LRFN5,ZIC2" Pubmed 16280634 Gliogenic radial glial cells show heterogeneity in the developing mouse spinal cord. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "FABP7,TUBB3,NKX2-2,PAX6,SLC1A3" Pubmed 14648547 Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "OLIG1,OLIG2,NKX2-2,PDGFRA,S100B" Pubmed 12750892 "The SLC32 transporter, a key protein for the synaptic release of inhibitory amino acids." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SLC32A1,GAD1,GAD2,RAB3A,SYT1" Pubmed 9115257 SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLGAP2,DLGAP1,DLGAP3,DLG3,DLG4" Pubmed 18703708 Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "STX1B,SNAP25,STX1A,STXBP1,SYT1" Pubmed 9920659 Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GRM1,GRM2,GRM3,GRM5,GRM7" Pubmed 17024414 Expression of glial progenitor markers p75NTR and S100 protein in the developing mouse parathyroid gland. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CHGA,TUBB3,GFAP,SOX10,UCHL1" Pubmed 10896954 The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ARHGEF7,ARHGEF6,GIT2,GIT1,PAK3" Pubmed 15870285 Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NCOR1,NCOR2,NR3C1,NFE2L2,PPARA" Pubmed 21525288 Axon formation in neocortical neurons depends on stage-specific regulation of microtubule stability by the dual leucine zipper kinase-c-Jun N-terminal kinase pathway. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,CALB2,MAPT,MAPK8,MAP3K12" Pubmed 9115241 Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 23776550 Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "MSI1,PTCH1,SOX1,SOX2,SOX3" Pubmed 15037614 Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "APBA2,APBB1,APP,CLSTN1,CLSTN2" Pubmed 25818041 Diagnostic yield of genetic testing in epileptic encephalopathy in childhood. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "PCDH19,KCNQ2,SCN2A,SCN8A,STXBP1" Pubmed 28130356 "A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "LRRC7,CACNB2,CAMK2A,CAMK2B,GRM5" Pubmed 18848628 Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "TUBB3,GFAP,MAP2,NEUROD1,RELN" Pubmed 24736997 "A novel protein, CHRONO, functions as a core component of the mammalian circadian clock." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ARNTL,CIART,CLOCK,CRY2,NR3C1" Pubmed 7546735 Pax3: a paired domain gene as a regulator in PNS myelination. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GFAP,L1CAM,MBP,NCAM1,S100B" Pubmed 25575549 Single-cell-level spatial gene expression in the embryonic neural differentiation niche. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "MDGA1,RCOR2,PAX6,SATB2,NR2E1" Pubmed 9856994 Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NRXN3,NRXN1,NXPH3,NXPH2,NXPH1" Pubmed 20019668 mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DCTN1,DYNC1I1,KIF5A,KIF5C,KLC1" Pubmed 23615280 A dynamic code of dorsal neural tube genes regulates the segregation between neurogenic and melanogenic neural crest cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DCT,FABP7,TUBB3,KIT,MITF" Pubmed 22215812 "Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "TUBB3,GFAP,RET,SOX10,UCHL1" Pubmed 10810084 Comparative genome mapping in the sequence-based era: early experience with human chromosome 7. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SEPT7,DOCK4,RASA4,ETV1,ICA1" Pubmed 10375501 Sonic hedgehog regulates the growth and patterning of the cerebellum. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,FABP7,GFAP,GLI2,ZIC1" Pubmed 10964956 Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,CALB2,L1CAM,NCAM1,PAX6" Pubmed 22084111 "POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ATP1A1,ATP2A2,ATP2B1,SLC35G1,XPO1" Pubmed 20573893 Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CDK5R1,CDH2,CTNND1,CTNND2,DLG4" Pubmed 14727813 Fine mapping of the circling (cir) gene on the distal portion of mouse chromosome 9. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ZIC4,MAP4,MYL3,TMIE,ZIC1" Pubmed 16488402 Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NRG2,EGFR,ERBB2,ERBB4,NRG3" Pubmed 26397040 Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB2,DCC,GFAP,L1CAM,UNC5B" Pubmed 27076426 TARP ?-2 and ?-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CACNG3,CACNG2,GRIA1,GRIA2,GRIA4" Pubmed 15883194 Molecular constituents of neuronal AMPA receptors. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLG4,CACNG2,GRIA1,GRIA2,GRIA4" Pubmed 23353076 Pax6 regulates Tbr1 and Tbr2 expressions in olfactory bulb mitral cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "FABP7,TBR1,GAD1,NCAM1,PAX6" Pubmed 26269635 Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EFNB3,EPHB1,TBR1,RELN,ZIC2" Pubmed 10373452 "EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?" Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SYNJ1,DNM1,ITSN1,SNAP25,STX1A" Pubmed 17103415 Mash1 regulates the development of C cells in mouse thyroid glands. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ASCL1,TUBB3,NEUROD1,SST,UCHL1" Pubmed 22457488 The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "LHX2,GBX2,L1CAM,ROBO1,ROBO2" Pubmed 21368048 Glutamate receptor ?2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GRIA1,GRIA2,GRIA4,GRIN2D,GRM1" Pubmed 22504067 Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EGFR,OLIG2,ERBB2,ERBB4,PDGFRA" Pubmed 23596255 Sox2 requirement in sonic hedgehog-associated medulloblastoma. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "OLIG2,PAX6,SOX1,SOX2,SOX3" Pubmed 24512687 Cux2 acts as a critical regulator for neurogenesis in the olfactory epithelium of vertebrates. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ELAVL3,ELAVL4,HES5,NEUROD1,CUX2" Pubmed 21472479 "Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "AXIN2,LGR5,MYO7A,PROX1,SOX2" Pubmed 28514446 Identification of preoptic sleep neurons using retrograde labelling and gene profiling. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CCK,GAD2,PDYN,TAC1,SLC17A6" Pubmed 17093100 Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ALS2,DLG4,GRIA1,GRIA2,GRIN1" Pubmed 16481432 "Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GFAP,GJB1,MAG,MYO6,NEFH" Pubmed 16076873 Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "RASGRP1,RASGRP2,RAPGEF4,RAP1GAP,RAP1GAP2" Pubmed 27540587 A novel GABA-mediated corticotropin-releasing hormone secretory mechanism in the median eminence. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SLC12A5,SLC32A1,GABRG2,GAD1,SLC12A2" Pubmed 22138645 ?2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CHN1,CHN2,DPYSL2,TUBB3,MAP2" Pubmed 17854420 "Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SERPINA3,APBB1,CYP46A1,OLR1,VLDLR" Pubmed 12103442 Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GRIN1,GRIN2C,GRIN2D,MAP2,SYP" Pubmed 20939858 Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ELAVL3,ELAVL4,TUBB3,RET,TLR4" Pubmed 17960183 Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NRG2,EGFR,ERBB2,ERBB4,NRG3" Pubmed 17515609 Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "OLIG2,MBP,PLP1,SOX10,SOX11" Pubmed 27010057 Tubulinopathies Overview Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "TUBB3,TUBA8,TUBB2B,TUBB2A,TUBA1A" Pubmed 20668654 Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 11943148 The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GRIK1,GRIK3,GRM5,GRM7,GRM8" Pubmed 17376969 Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB2,ETV1,GAD1,SST,CUX2" Pubmed 25003238 Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GRM1,GRM5,KCND1,KCND2,P2RY1" Pubmed 16080114 Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GABRA2,GABRA4,GABRA5,GABRB3,GABRG1" Pubmed 12508309 Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "FABP7,RET,S100B,SOX10,UCHL1" Pubmed 12270041 Neuronal nitric oxide synthase expression in the mouse vomeronasal organ during prenatal development. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,NOS1,NPPA,TAC1,UCHL1" Pubmed 22941191 Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NBAT1,HACE1,BARD1,LMO1,CASC15" Pubmed 30038273 Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CCK,SLC32A1,PDYN,TAC1,SLC17A6" Pubmed 20387078 Smooth-muscle-specific expression of neurotrophin-3 in mouse embryonic and neonatal gastrointestinal tract. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ELAVL2,ELAVL3,ELAVL4,KIT,S100B" Pubmed 23870127 Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EPB41,EPB41L2,NUMA1,ANLN,GPSM2" Pubmed 11117530 Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NCOA1,MED24,MED1,RXRA,THRA" Pubmed 21849552 Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "APC,OLIG2,GFAP,SOX2,SOX10" Pubmed 10407040 Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CACNG2,GRIA1,GRIA2,GRIA4,NTRK2" Pubmed 15711057 "SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EGFR,TUBB3,GFAP,NCAM1,SOX2" Pubmed 24379252 "[Hereditary hypomelanocytoses: the role of PAX3, SOX10, MITF, SNAI2, KIT, EDN3 and EDNRB genes]." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EDN3,EDNRB,KIT,MITF,SOX10" Pubmed 19409494 Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DCC,NRCAM,PRPH,ROBO3,CNTN2" Pubmed 10449790 "theta, a novel gamma-aminobutyric acid type A receptor subunit." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GABRA1,GABRA2,GABRB1,GABRG1,GABRG2" Pubmed 11997254 Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLG2,DLG3,DLG4,KCNA4,KCNJ4" Pubmed 16272887 Analysis of hedgehog interacting protein in the brain and its expression in nitric oxide synthase-positive cells. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GAD1,GAD2,NOS1,PTCH1,HHIP" Pubmed 16267219 Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ALCAM,DCC,GAP43,GLI2,L1CAM" Pubmed 26110920 Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "SLC12A5,GABRG1,GFAP,SLC4A3,SLC12A2" Pubmed 26961948 Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB2,OLIG2,TBR1,SOX2,SST" Pubmed 28284905 Embryonic mosaic deletion of APP results in displaced Reelin-expressing cells in the cerebral cortex. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "APP,TBR1,GFAP,MAP2,RELN" Pubmed 15306553 Embryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouse. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NRG2,EGFR,ERBB2,ERBB4,NRG3" Pubmed 15183722 Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB1,TUBB3,PTCH1,CNTN2,ZIC1" Pubmed 9808458 "Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "HOMER3,GRIA1,GRIK1,GRM1,GRM5" Pubmed 21322090 Mash1 is required for the differentiation of AADC-positive type III cells in mouse taste buds. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ASCL1,NCAM1,HES6,SNAP25,UCHL1" Pubmed 25740311 Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ALK,EML1,TUBB3,EML4,TUBA1A" Pubmed 11511537 COUP-TFI: an intrinsic factor for early regionalization of the neocortex. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CDH8,EMX2,LSAMP,PAX6,RORB" Pubmed 8999968 Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "STX2,STX1B,SNAP25,STX1A,SYT1" Pubmed 9611234 "The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "NCOR1,NR1D2,TAF6,TAF9,SIN3B" Pubmed 21375603 "Neural stem cells are increased after loss of ?-catenin, but neural progenitors undergo cell death." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "AXIN2,ASCL1,TBR1,PAX6,PROX1" Pubmed 24560577 FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DCC,GBX2,ROBO1,ROBO2,SLIT1" Pubmed 15252009 "A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DNM1,DNM2,PACSIN1,FNBP1,TF" Pubmed 21962519 "Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CALB2,CNTNAP2,GAD1,GFAP,NPY" Pubmed 7605629 Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLX1,EMX2,FOXG1,MAP2,PAX6" Pubmed 17131200 Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "LARGE1,NCAN,SPOCK3,SUGP2,FCHO1" Pubmed 11517249 c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "APBA2,APBB1,APLP1,APP,MAPK8" Pubmed 20065300 "Expression and distribution of Na, K-ATPase isoforms in the human uterus." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,FXYD1" Pubmed 19915564 "Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "FABP7,TUBB3,MEGF11,MEGF10,PEAR1" Pubmed 7477295 Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "DLG2,DLG4,KCNA1,KCNA2,KCNA4" Pubmed 11438518 "Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin." Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "CACNA1B,RAPGEF4,RIMS1,SNAP25,SYT1" Pubmed 26391954 RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "ACTN1,PTBP2,DZIP1,WDR7,PUM2" Pubmed 18185516 Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "GABRA1,GABRA3,GABRA4,GABRA5,GABRB3" Pubmed 24038449 The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Pubmed 1.51E-04 1.00E+00 1.61E-02 2.08E-01 5 7 "EPHB1,NEUROD1,PAX6,PROX1,SOX2" Pubmed 29121065 Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase. Pubmed 1.51E-04 1.00E+00 1.62E-02 2.09E-01 19 79 "CLK4,AP2A1,PPFIA1,PPFIA3,CDK13,NUMB,NUMBL,DZIP3,ERC2,LNX1,CIT,MID1,KIF7,KLHL11,FBXO11,MYCBP2,ERC1,DNAJC9,ZNF24" Pubmed 21947380 Pancreatic islet and progenitor cell surface markers with cell sorting potential. Pubmed 1.51E-04 1.00E+00 1.62E-02 2.09E-01 19 79 "ALCAM,TMEM108,PROM1,DDR1,JAM2,SEZ6L2,EFNB3,DNER,LILRB4,DISP2,KCNK1,KIT,FXYD6,PAX6,PDGFRA,RETREG1,ZDHHC4,TNFRSF19,LMBRD1" Pubmed 18614015 A mitochondrial protein compendium elucidates complex I disease biology. Pubmed 1.54E-04 1.00E+00 1.65E-02 2.13E-01 130 982 "ABAT,ACADM,ACLY,AS3MT,METAP1D,SLC25A25,AK2,ABCD2,BBOX1,AMT,GPAM,ALDH4A1,ALDH7A1,BCS1L,DCAF5,BID,LDHD,SLC25A14,NFS1,AIFM1,TBRG4,ZBED5,SLC25A27,LETMD1,COX4I1,PNKD,CS,SNPH,EARS2,TOMM20,DBT,EXOG,FIS1,TMTC1,AASS,COQ7,MRPL37,MRPL10,DNAJC27,ECSIT,ACSL4,TOMM40L,FECH,ATP5PD,COQ5,APOPT1,PRELID3A,PHYHIPL,GALC,MTHFD2,ACSS1,GATM,ALDH1L1,NFU1,GFER,DHRS4,GK,GLDC,AIFM3,GPT2,GPD1,GPD2,TDRKH,HMGCL,CPT1C,IDH3A,IDH3B,IBA57,SFXN5,PACRG,MAOB,MOBP,MRPL42,MSRA,NDUFA5,ALDH1L2,NME4,NRDC,OGDH,OGG1,OPA1,PC,ETFRF1,DUSP26,SLC25A23,MTRF1L,SEPT4,POLG,TATDN3,CRLS1,FITM2,PRODH,NDUFS7,OCIAD1,QDPR,ACSS3,SLC25A41,OXR1,MRPS18A,SLC25A36,SUGCT,PRR5L,PTGR2,DGLUCY,SARS,HOGA1,SCP2,FOXRED1,SHMT2,NUBPL,MTERF2,EFHD1,SLC22A4,NAXD,KIF1B,ADHFE1,VAMP1,IQCE,NEU4,TK2,PDSS1,AMACR,TST,BCL2L13,MTCH1,CCDC136,NT5M,PDSS2,MRPL47,PAK5" Pubmed 21440680 Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. Pubmed 1.55E-04 1.00E+00 1.65E-02 2.14E-01 21 92 "SEMA7A,ATM,MPDZ,PRC1,OLIG1,CDHR1,FOXM1,SMC2,INSM1,MEIS2,MYCN,NEUROD1,NHLH1,PAX6,PDE2A,NXPH1,RELN,HES6,UNC5D,AKNA,TMPO" Pubmed 20473970 Identification of FBXO25-interacting proteins using an integrated proteomics approach. Pubmed 1.56E-04 1.00E+00 1.66E-02 2.15E-01 24 112 "ATP1A1,ATP1A2,ATP2A2,DBN1,FBXO25,EEF1A2,TUBB3,TUBB4A,PRMT5,GTF2IRD2,GFAP,TUBA1C,GSN,MYO5A,MYO6,NAP1L1,PFKP,SH3KBP1,MYH14,CXXC4,MPRIP,TUBB2A,TUBB1,XPO1" Pubmed 29321139 BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons Pubmed 1.62E-04 1.00E+00 1.74E-02 2.24E-01 12 38 "BMP7,BMPR1B,CALB1,CDH2,TUBB3,SMAD1,SMAD9,MAP2,MAPK3,MAPK8,SOX6,TJP1" Pubmed 19730683 The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. Pubmed 1.65E-04 1.00E+00 1.76E-02 2.28E-01 22 99 "ACHE,AMH,ARRB2,NCOR2,RTN3,ADGRV1,FGFR1,GHR,IGFBP1,IL6ST,JAK1,JAK2,KIT,MATN2,PMS2,PTCH1,PTHLH,PTH1R,KCNIP3,TCF12,THRA,MAP3K12" Pubmed 27869233 Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Pubmed 1.66E-04 1.00E+00 1.77E-02 2.29E-01 15 55 "PPP4R4,ARHGDIG,MATR3,LPAR6,USPL1,TUBA1B,AKAP3,TUBA1C,MXI1,PBRM1,NECAB1,RPL7L1,PLPP4,TUBA1A,RTN4" Pubmed 23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Pubmed 1.68E-04 1.00E+00 1.79E-02 2.31E-01 20 86 "GAS7,SNAP25-AS1,NCOR2,LRIG1,HS3ST2,EBF1,NSG2,GALC,GRM7,PTPN5,MATN2,PRTG,PDE4D,SERPINE2,WLS,RXRA,LHPP,KAZN,CSMD1,OSBP2" Pubmed 19191219 Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "ASCL1,OLIG2,TUBB3,DLL3,HES5,NEUROD1,HES6,SLC1A3,SOX2" Pubmed 20564261 Uncoupling of bait-protein expression from the prey protein environment adds versatility for cell and tissue interaction proteomics and reveals a complex of CARP-1 and the PKA Cbeta1 subunit. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "TUBA1B,TUBB4A,MAP2,PDPK1,PRKACB,PKIA,RAP1GAP,SYN1,SIK3" Pubmed 18367606 A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "CALB1,SLC32A1,DLX1,NEUROD1,PROX1,ZFHX4,RXRG,SLC6A1,SLC17A6" Pubmed 29086765 Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "SLC32A1,FLT1,TBR1,GABRB3,GAD1,GAD2,MAP2,WNT7A,SLC17A7" Pubmed 20237272 Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "AXIN2,FGF17,ETV1,FABP7,TUBB3,FGFR3,TBR1,MEST,MAPK3" Pubmed 20457670 Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in mice. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "TUBB3,GBX2,STMN2,MAPT,NPY,NTRK2,NTRK3,DICER1,UCHL1" Pubmed 19357274 Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "ASCL1,OLIG2,TUBB3,GBX2,NKX2-2,NPY,PTCH1,SOX1,SOX2" Pubmed 23223237 The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "ASCL1,OLIG2,FGFR3,ALDH1L1,GFAP,HES5,NFIA,SOX1,SOX2" Pubmed 20301402 Parkinson Disease Overview Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "PLA2G6,FBXO7,SNCAIP,MAPT,LRRK2,ATXN2,SNCA,ATP13A2,UCHL1" Pubmed 10021345 The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "CDH2,ERBB4,MEF2C,MYCN,MYH6,MYH7,MYL3,NF1,NPPA" Pubmed 21926974 Genome-wide association study identifies five new schizophrenia loci. Pubmed 1.71E-04 1.00E+00 1.81E-02 2.34E-01 9 23 "ANK3,CALN1,MMP16,PIK3C2A,PLCB2,CNNM2,PTPRG,TCF4,CSMD1" Pubmed 26378152 LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation. Pubmed 1.77E-04 1.00E+00 1.87E-02 2.42E-01 11 33 "ATP2A2,EDN1,KCNA4,KCNB1,KCND2,KCND3,KCNH2,KCNJ5,KCNJ11,KCNK3,MYH6" Pubmed 24204828 Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. Pubmed 1.77E-04 1.00E+00 1.87E-02 2.42E-01 11 33 "ARHGEF7,MAGI1,PLXNA4,SNX29,EMX2,NRG3,SERP2,FAT3,SLC22A23,CLSTN2,PARP11" Pubmed 25064009 Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Pubmed 1.77E-04 1.00E+00 1.87E-02 2.42E-01 11 33 "DLG2,TMEM175,MAPT,VPS13C,RIT2,LRRK2,STX1B,SNCA,SYT11,TMEM163,FAM47E" Pubmed 18067320 "Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications." Pubmed 1.82E-04 1.00E+00 1.92E-02 2.48E-01 10 28 "ARHGEF7,BTK,DLG4,FYB1,FYN,MBP,MPP2,ITSN1,VAV1,VAV2" Pubmed 19906857 Lhx2 links the intrinsic and extrinsic factors that control optic cup formation. Pubmed 1.82E-04 1.00E+00 1.92E-02 2.48E-01 10 28 "AXIN2,BMP7,LHX2,VAX2,SMAD1,SMAD9,MITF,PAX6,MAPK3,SOX2" Pubmed 21779340 Genetic variations strongly influence phenotypic outcome in the mouse retina. Pubmed 1.86E-04 1.00E+00 1.97E-02 2.55E-01 13 44 "ABCD2,RGS9,MITF,GNG2,PRRX1,MED1,RORB,ZNF365,SCMH1,NSD1,TP53BP1,NR2C2,SEMA3B" Pubmed 16919471 Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. Pubmed 1.86E-04 1.00E+00 1.97E-02 2.55E-01 13 44 "CRMP1,TENM4,TENM1,EMX2,MTSS1L,TUBA1B,RACK1,TUBA1C,CELF3,PAX6,TCF4,THRA,UCHL1" Pubmed 16110338 A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome. Pubmed 1.92E-04 1.00E+00 2.03E-02 2.62E-01 18 74 "RGS9,ENTPD4,EPB41L1,CDHR1,DLL3,DKK3,ELOVL2,PYGM,IQSEC3,ZDHHC14,RPE65,EPHA10,RXRG,MAPK8IP3,CRB1,SMUG1,CCDC136,SLC38A1" Pubmed 17148452 "Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2." Pubmed 1.98E-04 1.00E+00 2.10E-02 2.71E-01 20 87 "CCNT1,AIFM1,PSD2,DOCK7,IPO5,MOV10,PIK3C2A,XRN1,PMS2,PPP2R2B,PPP3CB,PPP3CC,REV3L,SBF1,SMARCA4,MMS19,PSD3,UBC,AMOT,XPO1" Pubmed 18240029 Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. Pubmed 2.00E-04 1.00E+00 2.11E-02 2.73E-01 36 200 "ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,C5,CHRM1,CHRM4,CNR1,DRD1,LPAR6,CALCRL,GNAO1,GNAS,LPAR4,GPER1,HRH3,HTR2A,HTR5A,P2RY13,OPRL1,P2RY1,PDYN,GNG2,PENK,PTHLH,PTH1R,RGR,SST,SSTR1,SSTR2,VIPR2,P2RY12" Pubmed 26426291 Comprehensive interactome of Otx2 in the adult mouse neural retina. Pubmed 2.01E-04 1.00E+00 2.12E-02 2.73E-01 14 50 "CDK13,ZNF385A,KAT8,ZNF512,ZNF638,DIDO1,PSIP1,HNRNPK,NFIX,RORB,RPL38,SFPQ,TMPO,ZSCAN26" Pubmed 19807924 Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Pubmed 2.01E-04 1.00E+00 2.12E-02 2.73E-01 14 50 "BTK,CACNB4,KALRN,DOCK4,SRGAP3,DLG2,SORBS3,FYB1,FYN,PIK3R1,SH3GL3,SAMSN1,DNMBP,ARHGAP9" Pubmed 20301607 Deafness and Hereditary Hearing Loss Overview Pubmed 2.01E-04 1.00E+00 2.12E-02 2.74E-01 17 68 "ATP2B2,FAM189A2,TJP2,WHRN,COL11A2,GSDME,USH1C,KCNJ10,MYO6,MYO7A,TMIE,GPSM2,POU3F4,STRC,RDX,MYH14,PCDH15" Pubmed 19423573 A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea. Pubmed 2.06E-04 1.00E+00 2.17E-02 2.81E-01 29 149 "SERPINA3,ALAD,ANXA7,PRX,PDXK,CADM3,CALB2,INA,AIF1L,DPYSL2,ENO2,GFAP,CBX1,GSTM5,HNRNPK,HPCA,HSPA1L,IDH3A,INPP1,KCNMA1,STMN1,MBP,NEFH,NUCB1,PRPH,EPB41L3,TF,UCHL1,TUBA1A" Pubmed 18676680 Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. Pubmed 2.13E-04 1.00E+00 2.24E-02 2.90E-01 59 381 "AXIN2,PLA2G6,ALAD,AMT,APAF1,APC,ATM,BARD1,BLM,CBR1,CBS,CCNH,CD86,SCARB1,CD81,CDC25B,CSF1R,RGS6,CTH,CX3CR1,CYBB,MATR3,DRD1,EDN1,EFNB3,EGFR,RGS17,ERBB2,ERCC2,MTHFD2,ALDH1L1,GHR,HMGCR,HSD17B1,IGF1,IGFBP1,IL6R,IL12A,LMO2,MEST,MSR1,MTR,MX1,MYO5A,NCF2,OGG1,P2RX7,ABCB1,PMS2,MASP1,RAD52,RET,RNASEL,FBXW7,RXRA,AMACR,WRN,XRCC4,SLC30A4" Pubmed 23864651 The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity. Pubmed 2.14E-04 1.00E+00 2.25E-02 2.91E-01 12 39 "APLP1,SYNGR3,CD81,APH1A,CEND1,FDFT1,GPR37,STMN1,NRGN,PIGG,PAQR6,CAND2" Pubmed 29348145 FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. Pubmed 2.14E-04 1.00E+00 2.25E-02 2.91E-01 12 39 "CIART,LONRF1,SACS,AASS,RAPGEF4,SYT9,NACA,ABCB1,LRRC4,RGL1,AGTPBP1,HSPBP1" Pubmed 27534441 Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Pubmed 2.14E-04 1.00E+00 2.25E-02 2.91E-01 12 39 "WHRN,ADGRV1,ECSIT,IDH3A,MAG,MYO6,MYO7A,PCSK1,TMEM145,SLC12A2,PLD4,SLC4A10" Pubmed 21966449 "High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies." Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CALB2,CDH2,LGI1,GABRB3,JPH4,GRIA1,ARX,SNRPN" Pubmed 26965927 Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CALB1,CNGA3,GFAP,GLUL,PAX6,PRKCB,PRKCG,CCDC136" Pubmed 27770010 Six3 dosage mediates the pathogenesis of holoprosencephaly. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "ASCL1,EBF1,FOXG1,GAD1,GBX2,PAX6,PROX1,PTCH1" Pubmed 22387004 Arx is required for normal enteroendocrine cell development in mice and humans. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CCK,DCLK1,CHGA,NEUROD1,NKX2-2,PAX6,ARX,SST" Pubmed 15733084 Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-type-dependent expression in the developing mouse CNS. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CALB1,CALB2,DLX1,TBR1,PAX6,RELN,SATB1,SATB2" Pubmed 28880149 Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "ERBB2,LAMA2,MBP,POU3F2,MAPK3,SOX2,SOX10,TSC1" Pubmed 28688895 Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "PTCH2,BMPR1B,OLIG2,GLI2,NKX2-2,PAX6,PTCH1,HHIP" Pubmed 11342430 A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "RGS20,RGS11,RGS9,RGS6,RGS17,RGS3,RGS4,RGS7" Pubmed 28433741 Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "ADORA2A,DRD1,PPP1R1B,GPR88,PENK,RGS4,SST,TAC1" Pubmed 23332756 The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "OLIG2,FOXG1,GLI2,KIF3A,NKX2-2,PAX6,PTCH1,GPR161" Pubmed 19632216 Patterning of ventral telencephalon requires positive function of Gli transcription factors. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "EBF1,TUBB3,FOXG1,GAD1,NKX6-2,GLI2,PAX6,PDGFRA" Pubmed 27719760 BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "BLOC1S6,EGFR,FABP7,TUBB3,TBR1,HES5,BLOC1S2,PAX6" Pubmed 15024025 Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CASK,DLG2,DLG3,DLG4,DMD,DTNA,MPP6,KCNJ4" Pubmed 28154153 Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "AXIN2,OLIG2,FOXG1,NKX2-2,PAX6,POLR2F,PTCH1,TACC1" Pubmed 26212662 Boundary Caps Give Rise to Neurogenic Stem Cells and Terminal Glia in the Skin. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "TUBB3,MBP,MITF,MSI1,NTRK2,NTRK3,SOX10,UCHL1" Pubmed 19692620 Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CALB1,CALB2,GAD1,GAD2,GLUL,PAX6,PROX1,SLC6A9" Pubmed 21925491 Impaired stria vascularis integrity upon loss of E-cadherin in basal cells. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "AXIN2,ATP1A1,CDH2,DCT,SLC12A6,KCNJ10,CLDN11,TJP1" Pubmed 16679559 Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "FABP7,GAP43,GDF1,GRIN1,HES5,NBL1,PRKAR1B,MEIS3" Pubmed 23166209 Impact of ancestry and common genetic variants on QT interval in African Americans. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "OSBPL6,SLC4A4,NOS1AP,CEP85L,FGF14,KCNH2,MBP,PDZRN3" Pubmed 23677977 A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "GPRASP1,ARMCX2,ZMAT1,TCEAL6,BEX1,BHLHB9,BEX4,TMEM163" Pubmed 29679559 Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "EMX2,FOXG1,GAD1,RORB,ARX,SST,TRH,VIPR2" Pubmed 11748150 The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum. Pubmed 2.17E-04 1.00E+00 2.26E-02 2.92E-01 8 19 "CDH8,SLIT2,EFNB3,EPHA5,FABP7,ROBO1,ROBO2,SLIT1" Pubmed 17643375 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Pubmed 2.26E-04 1.00E+00 2.35E-02 3.04E-01 60 390 "SDE2,AK2,LRCH2,CCAR2,DDX3Y,CCNH,CCNT1,ARHGEF1,CDK11B,ARHGEF2,AKAP7,TBPL1,RBM39,MATR3,INTS1,MED24,DDX46,DNM2,MRPL37,PRMT5,SYNCRIP,NOP56,KHDRBS3,TUBA8,SRCAP,HNRNPK,HSPA1L,MYLK2,DOCK7,KPNA5,IPO5,MOV10,HNRNPM,PCBP3,NUMA1,ANLN,SYTL2,KHDRBS2,RPL38,RXRG,SAFB,SUPT20H,PUF60,SMARCA4,SMARCC2,SNRPN,SPTAN1,ERBIN,TAF6,TAF9,FBXW11,TCEA1,EHBP1,ACTR6,PRMT8,TBC1D15,XPO1,POLR3H,INTS3,NELFE" Pubmed 18577758 Dissociation of heterotrimeric g proteins in cells. Pubmed 2.29E-04 1.00E+00 2.38E-02 3.07E-01 33 179 "ADCYAP1R1,ADORA1,ADORA3,ADRA1B,CCK,CHRM1,CHRM4,CNR1,EDN3,EDNRA,EDNRB,LPAR6,GALR1,MCHR1,PTGDR2,HRH3,HTR2A,HTR5A,P2RY13,NPY,OPRL1,P2RY1,GNG2,PENK,PTAFR,SST,SSTR1,SSTR2,TAC1,TAC3,TRH,VIPR2,P2RY12" Pubmed 28172500 Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice. Pubmed 2.38E-04 1.00E+00 2.48E-02 3.20E-01 11 34 "SEMA6A,VCAN,PLXNA4,SEMA6C,FLT1,HAS2,MYH6,NCAM1,SEMA6D,TEK,TIE1" Pubmed 25429064 Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Pubmed 2.39E-04 1.00E+00 2.49E-02 3.22E-01 27 136 "SYN3,ZFAT,LCORL,CDK10,SV2A,DNM2,STARD3NL,DNAJC27,EFEMP1,FAM184B,GHR,GLI2,ZNF638,ATF7,PLCD4,IGF1,MEF2C,RASGEF1B,PTCH1,RBBP8,ADAMTS17,FBXW11,ATP13A2,HHIP,TNS1,ZBTB38,ADAMTSL3" Pubmed 29180410 "Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,TUBB3,TBR1,MAP2,PPP4R3A,SOX2" Pubmed 11044402 Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GFAP,GFRA1,GFRA2,STMN2,PRPH,RET" Pubmed 21743471 Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GAD1,GAD2,PAX6,SLC6A9,STX1A,SATB2" Pubmed 19079261 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "STK33,SH2B1,MEX3B,NEGR1,KCTD15,FTO" Pubmed 12727448 The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB2,TBR1,GAD1,GAP43,NCAM1,RELN" Pubmed 25374362 The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CADPS,CPLX2,CPLX1,SNAP25,STX1A,SYT1" Pubmed 22399681 Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ALCAM,SLIT2,L1CAM,ROBO1,ROBO2,SLIT1" Pubmed 16421308 Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "EFNB3,EPHB1,TUBB3,GAP43,GFAP,CNTN2" Pubmed 17942321 Expression of connexin30.2 in interneurons of the central nervous system in the mouse. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ACHE,CALB1,GFAP,KCNC1,S100B,SST" Pubmed 27466379 The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "SLIT2,OLIG2,ROBO1,ROBO2,SLIT1,SYP" Pubmed 27111087 C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB2,CDH2,TBR1,RAPGEF1,MAP2,MAPT" Pubmed 11842093 "Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ACTN1,ACTN2,FLNC,MYOZ2,PPP3CA,PPP3CB" Pubmed 17021016 Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "DGKZ,DGKD,DGKI,DGKB,DGKG,EGFR" Pubmed 19743445 Expression of Pou3f3/Brn-1 and its genomic methylation in developing auditory epithelium. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "AQP4,TUBB3,MYO7A,POU3F2,PROX1,SLC12A2" Pubmed 21944720 Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CDK5R1,WASF1,DLG4,GFAP,GRIN1,SYN1" Pubmed 10631168 Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "NRP2,CALB2,FOXG1,GFAP,PROX1,TCF7L2" Pubmed 17117437 Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "FGFR1,FGFR3,HES5,MYO6,MYO7A,PROX1" Pubmed 21949878 Aebp2 as an epigenetic regulator for neural crest cells. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ZEB2,EDN3,EDNRB,MITF,RET,SOX10" Pubmed 25834049 "Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity, and nociception." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,GAD1,PRKCG,RELN,SST,TACR1" Pubmed 28673820 PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "KIAA0586,GLI2,NKX2-2,PAX6,PRKACB,PTCH1" Pubmed 15322115 Protein kinase Cdelta regulates apoptosis via activation of STAT1. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CAMK2G,EGFR,FGFR3,JAK1,JAK2,PRKCG" Pubmed 18547559 FGF8 signaling patterns the telencephalic midline by regulating putative key factors of midline development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "LHX2,ETV1,ZIC4,MEST,ZIC1,ZIC2" Pubmed 19389374 "Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "BMP7,FGFR1,FGFR3,PTCH1,PTHLH,TRPS1" Pubmed 25151262 Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GFAP,GLUL,NFIA,PAX6,S100B,SOX10" Pubmed 19302145 Secreted TARSH regulates olfactory mitral cell dendritic complexity. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CAMK2B,PLPPR4,PRUNE2,MEF2C,RGS4,PCDH20" Pubmed 29374155 Kruppel-like factor 4-dependent Staufen1-mediated mRNA decay regulates cortical neurogenesis. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "TUBB3,TBR1,MAP2,PAX6,STAU1,SATB2" Pubmed 12933680 "Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "NKX2-2,PAX6,PCSK1,PCSK2,POU3F4,SST" Pubmed 20484636 Developmental origin of the neuronal subtypes that comprise the amygdalar fear circuit in the mouse. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,CALB2,FOXG1,TBR1,MEF2C,MEIS2" Pubmed 15964824 Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GAP43,L1CAM,NCAM1,RELN,RORB,CNTN2" Pubmed 11069887 Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "DCT,TUBB3,PAX6,PROX1,SOX2,STX1A" Pubmed 19523119 "High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CASK,NRXN2,ABI2,L1CAM,SEPT4,SYT1" Pubmed 15295034 LIM genes parcellate the embryonic amygdala and regulate its development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "LDB2,LHX2,LMO1,LMO2,NEUROD1,PLP1" Pubmed 24411736 Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CNTNAP1,CNTNAP2,CHL1,KIRREL3,L1CAM,NRCAM" Pubmed 18626943 Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,CALB2,GLUL,PAX6,SOX2,STX1A" Pubmed 10707974 Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ACHE,ERBB4,TUBB3,SOX10,SYP,UCHL1" Pubmed 9647694 "CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "NRXN2,DLG4,GRIN1,GRIN2C,GRIN2D,KCNJ10" Pubmed 14499647 TACE is required for fetal murine cardiac development and modeling. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "EGFR,ERBB4,MYH6,MYH7,NPPA,MAPK8" Pubmed 18302773 Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "HES5,MYO6,PROX1,HES6,HEY1,HEY2" Pubmed 25313962 RBM24 is a major regulator of muscle-specific alternative splicing. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "USP28,NUMB,NUMBL,ABCC9,NACA,FXR1" Pubmed 21563316 Synaptic vesicle trafficking and Parkinson's disease. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "SYNJ1,SNCAIP,LRRK2,SNCA,SYT11,SYN1" Pubmed 17482496 Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "HCN2,MEF2C,MYH6,MYH7,NPPA,HCN1" Pubmed 17661397 Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,DKK3,PAX6,PRKCB,PRKCG,S100B" Pubmed 10872802 Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "BTK,FYN,JAK1,JAK2,KIT,KITLG" Pubmed 15837802 Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ATP1A3,EGR3,PRPH,SSTR2,HEY1,TMEM178A" Pubmed 23283686 Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "TBR1,MEF2C,FEZF2,SOX5,SATB2,ZFPM2" Pubmed 28239148 Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ACTN2,CDH2,AMOTL2,FAT4,MESP1,AMOT" Pubmed 9247261 Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "LHX2,DLX1,PPP1R1B,GAD1,MAP2,POU3F4" Pubmed 23637329 Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "SV2B,SV2A,DLG4,KIRREL3,GNAO1,KIRREL1" Pubmed 28475893 Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB2,FABP7,TBR1,PAX6,FLRT2,FLRT1" Pubmed 19235102 Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CACNA1A,ATN1,PPP2R2B,ATXN1,ATXN2,ATXN7" Pubmed 29082311 MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "TBR1,GFAP,MAP2,NEFH,PAX6,RELN" Pubmed 27452274 Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrn?3 in Cerebellar Granule Neuron progenitors during development. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "ASTN1,NRXN1,PAX6,NLGN3,ASTN2,SLC17A7" Pubmed 27693255 "Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome." Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GAD1,GAD2,S100B,PCDH20,SLC17A7,SLC17A6" Pubmed 17828260 COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CDH8,TBR1,MDGA1,PAX6,FEZF2,RORB" Pubmed 24107967 GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "GFRA1,MAPK3,RET,SOX10,UCHL1,TMEM163" Pubmed 19874786 SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB1,DCTN1,TBR1,RELN,SYNE2,SYNE1" Pubmed 21220099 CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "CALB2,DLX1,TBR1,RELN,SATB2,CUX2" Pubmed 12872126 Emx2 patterns the neocortex by regulating FGF positional signaling. Pubmed 2.46E-04 1.00E+00 2.49E-02 3.22E-01 6 11 "FGF17,CDH8,EMX2,ETV1,FGFR3,RORB" Pubmed 22745311 ?-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "AXIN2,ASCL1,LHX2,GBX2,NEUROD1,NKX2-2,PAX6,PTCH1,SOX2" Pubmed 24852369 Atmin mediates kidney morphogenesis by modulating Wnt signaling. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "DYNLL1,PRKCZ,PTCH1,RET,ATMIN,DAAM2,SGK3,VANGL2,IFT88" Pubmed 21655085 FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "BMP7,ENTPD2,EGFR,TUBB3,FGFR1,FGFR3,NCAM1,SOX2,TMEM163" Pubmed 21420948 Rbpj regulates development of prosensory cells in the mammalian inner ear. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "FOXG1,RBPJ,HES5,MYO6,MYO7A,PROX1,SOX2,HEY1,HEY2" Pubmed 21536733 A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "ASCL1,FOXM1,ATCAY,SHC3,RCOR2,PAK3,SYT4,TP53BP1,CELF4" Pubmed 28729440 The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "AXIN2,BMP7,CELSR3,TUBB3,FOXG1,MITF,PAX6,FZD3,VANGL2" Pubmed 17131407 Reduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "ACHE,ZEB2,EDN3,EDNRB,GFRA1,GFRA2,L1CAM,RET,SOX10" Pubmed 17307970 Overview of PDEs and their regulation. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE1B" Pubmed 24710276 PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation. Pubmed 2.50E-04 1.00E+00 2.51E-02 3.24E-01 9 24 "OSBPL1A,ATM,ATP1B3,PDE4DIP,DYRK1A,TRAPPC13,PPP4R3A,SON,TJP1" Pubmed 10508479 Antigens recognized by autologous antibody in patients with renal-cell carcinoma. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 16 63 "BRAP,ZNF608,NCOA1,USH1C,KCTD3,IRAK4,HSP90AA1,RBPJ,LIMS1,NEK1,PFKFB3,PPP2R5C,ZC3H14,KIF21A,TP53BP2,UBE3A" Pubmed 24728074 "Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome." Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 16 63 "BCAR3,SOCS6,SOCS5,FGR,GAB1,KIT,MATK,SHC3,PIK3R1,SH3BP2,SHC4,TNS2,TNS1,VAV1,VAV2,SHD" Pubmed 19884258 Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 14 51 "AXIN2,NR0B1,MMD2,CBLN1,DCLK1,COL9A3,DOCK4,DAPK1,DTNA,SERPINE2,PTPRE,SOX8,ZFPM2,ACTR6" Pubmed 21122108 Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 14 51 "MIER1,NCOR1,IP6K1,ELMSAN1,EZH1,FOXG1,IP6K2,HNF4G,CLIP1,ARX,TRERF1,CUX2,HEY2,KAT6A" Pubmed 24586484 Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CLTB,TUBD1,MAPT,NASP,SOX6,TRA2B,TCF4" Pubmed 10479680 Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "GRIN2C,GRIN2D,KCND1,KCND2,KCND3,KCNJ4,KCNJ10" Pubmed 18628400 Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "ACADM,ATP2A2,COX4I1,PPARGC1A,MYH6,NPPA,PFKP" Pubmed 15629702 Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "OLIG1,OLIG2,NKX6-2,NKX2-2,PDGFRA,DBX2,SOX10" Pubmed 26839344 Proper closure of the optic fissure requires ephrin A5-EphB2-JNK signaling. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "VAX2,EFNA2,EFNA3,EFNB3,EPHB1,MAPK8,MAPK9" Pubmed 26025376 Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "ZIC4,ALDH1L1,GFAP,GLUL,SOX2,ZIC1,ZIC3" Pubmed 26395878 Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,CALB2,OLIG2,FOXG1,GAD1,GFAP,SOX10" Pubmed 9630982 Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "BIN1,SORBS3,SORBS1,DBNL,ITSN1,SH3GL2,SH3GL3" Pubmed 22513377 Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "ASCL1,CALB1,TBR1,GFAP,NEUROD1,PAX6,ZIC1" Pubmed 18403412 MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "TUBB3,TBR1,GFAP,PRKCZ,SATB2,TJP1,CRB2" Pubmed 24639535 Role of BRCA1 in brain development. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,TUBB3,TBR1,GFAP,PAX6,RELN,SOX2" Pubmed 24035762 Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "SV2A,DLG4,GFAP,L1CAM,MAP2,NTRK2,TF" Pubmed 21561989 Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "ASCL1,TUBB3,GAD1,GFAP,MAP2,NCAM1,SOX2" Pubmed 17444492 Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CACNA1B,CRMP1,EBF1,FGF12,GAP43,MEIS2,SNCA" Pubmed 19144635 Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "AMPH,BIN1,CLTA,EGFR,TNK2,MAGI3,HECW1" Pubmed 27721240 Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "GIT2,KIAA0319,GPR34,P2RY13,PDE3B,MED1,P2RY12" Pubmed 26940020 "Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9." Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,OLIG2,FABP7,MBP,PAX6,PDGFRA,SOX10" Pubmed 18224708 Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB2,CDH2,EGFR,L1CAM,PAX6,STX1B,STX1A" Pubmed 22337526 Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "OLIG2,GFAP,GJB1,MAG,MBP,SOX2,SOX10" Pubmed 16382105 International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16" Pubmed 24516396 Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "GFRA1,GFRA2,NTRK2,NTRK3,RET,TRPC3,UCHL1" Pubmed 19680541 CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,TUBB3,GFAP,GRM1,MYO6,SLC1A3,SYP" Pubmed 25993409 Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "ASCL1,CALB1,CALB2,GAD1,NKX2-2,TAL1,SLC17A6" Pubmed 18272593 Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "OLIG2,TUBB3,GLI2,NKX2-2,PAX6,PTCH1,IFT88" Pubmed 20064391 Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "EDIL3,GFRA1,GFRA2,MAPT,NTRK2,NTRK3,RET" Pubmed 18385258 Dynamic regulation of the expression of neurotrophin receptors by Runx3. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,CALB2,NTRK2,NTRK3,RET,SST,SLC17A7" Pubmed 24125957 Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CALB1,CALB2,PAX6,PRKCB,PRKCG,PROX1,SOX2" Pubmed 18507827 "Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance." Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "CDH2,GFAP,L1CAM,NCAM1,PAX6,STX1B,STX1A" Pubmed 11504923 HIV envelope gp120 activates human arterial smooth muscle cells. Pubmed 2.52E-04 1.00E+00 2.51E-02 3.24E-01 7 15 "PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10" Pubmed 11991713 An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia. Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "ASPH,CLDN10,DCT,MBNL2,IPO5,HS6ST3,NALCN,DZIP1,DOCK9,ZIC2" Pubmed 23396134 Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "CACNA1D,TJP2,TOX,GRIA4,SHISA6,LAMA2,RASGRF1,ZMAT4,RORB,ZIC2" Pubmed 29137925 Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation. Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "CALB1,LHX2,EBF1,GAD1,GAD2,GLUL,NEUROD1,PAX6,SLC6A9,SOX2" Pubmed 15071553 "Biology, structure and mechanism of P-type ATPases." Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP8A1,ATP2C1" Pubmed 16123981 Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "FGF17,VPS26C,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,TRHDE" Pubmed 21834987 "Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration." Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "FMNL2,CFAP410,FMNL3,ZMYM4,CAMSAP1,WASF3,SH3KBP1,FITM2,LARP4,ARC" Pubmed 23652001 An isoform of retinoid-related orphan receptor ? directs differentiation of retinal amacrine and horizontal interneurons. Pubmed 2.53E-04 1.00E+00 2.51E-02 3.24E-01 10 29 "CALB1,GFAP,GLUL,NEUROD1,NPY,PAX6,PROX1,RORB,SLC6A9,STX1A" Pubmed 19625176 PTEN identified as important risk factor of chronic obstructive pulmonary disease. Pubmed 2.65E-04 1.00E+00 2.63E-02 3.40E-01 58 376 "AXIN2,PLA2G6,ALAD,AMT,APAF1,APC,ATM,BARD1,BLM,CBR1,CBS,CCNH,CD86,SCARB1,CD81,CDC25B,CSF1R,RGS6,CTH,CX3CR1,CYBB,MATR3,DRD1,EDN1,EGFR,RGS17,ERBB2,ERCC2,MTHFD2,ALDH1L1,GHR,HMGCR,HSD17B1,IGF1,IGFBP1,IL6R,IL12A,LMO2,MEST,MSR1,MTR,MX1,MYO5A,NCF2,OGG1,P2RX7,ABCB1,PMS2,MASP1,RAD52,RET,RNASEL,FBXW7,RXRA,AMACR,WRN,XRCC4,SLC30A4" Pubmed 23535729 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Pubmed 2.74E-04 1.00E+00 2.72E-02 3.51E-01 18 76 "METAP1D,SNX32,MRTFA,N4BP2L1,RAB3C,SLC4A7,DLX1,EBF1,AP4B1,TOX3,HNF4G,PDE4D,FTO,PTHLH,EMID1,ZNF365,TCF7L2,STXBP4" Pubmed 23891004 Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins. Pubmed 2.74E-04 1.00E+00 2.72E-02 3.51E-01 20 89 "FMNL2,FMNL3,CHD1L,DUSP9,DNAJB6,USPL1,ERCC2,NSRP1,GGT7,MSL1,PCBP3,ELP2,SON,MMS19,ELP5,TSC1,TSC2,TUBB2A,SF1,WNK1" Pubmed 24163370 "The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition." Pubmed 2.90E-04 1.00E+00 2.87E-02 3.71E-01 46 281 "NCKAP5,HECW2,RTL9,OSBPL8,EP400,SCAPER,CDC27,KIAA0586,MED12,PHC2,EEF1D,ACSL4,SCML2,PRMT5,KAT8,BAIAP2,ZCCHC17,SPECC1,USP21,FAM120B,SRCAP,ZNF638,GRB10,DIDO1,CIT,MAP2,MARK1,KCTD6,CHAMP1,PC,XRN1,PKN2,RBBP6,ZMAT4,MORC4,PBRM1,ZC3H14,SUPT20H,KDM4D,RADIL,SP2,HECW1,CABIN1,ZMYND8,TSC2,SPHK2" Pubmed 29091030 CHIP as a membrane-shuttling proteostasis sensor. Pubmed 3.06E-04 1.00E+00 3.03E-02 3.91E-01 16 64 "BIN1,ARHGAP33,DNAJB6,BAIAP2,VTI1B,WDR83,SRCAP,PRRC2B,KIFC3,GPSM2,STAU1,DNAJC9,TAF6,FBXW11,TCF4,AAAS" Pubmed 17626619 An analysis of expression patterns of genes encoding proteins with catalytic activities. Pubmed 3.06E-04 1.00E+00 3.03E-02 3.91E-01 16 64 "CA4,CA8,CA12,CS,ENO2,ACSS1,GCK,LOXL3,IDH3A,IDH3B,OGDH,PFKP,PGAM2,PKM,CA14,CA10" Pubmed 27664421 Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Pubmed 3.17E-04 1.00E+00 3.14E-02 4.05E-01 11 35 "ARRB1,ARRB2,CDH2,TUBB3,GFAP,MAP2,PAX6,MAPK8,SLC1A3,SATB2,TJP1" Pubmed 25615642 Galnt1 is required for normal heart valve development and cardiac function. Pubmed 3.17E-04 1.00E+00 3.14E-02 4.05E-01 11 35 "GALNT16,GALNT13,HAPLN1,VCAN,EGFR,GALNT15,SMAD1,MAPK3,GALNT10,GALNT17,ADAMTS9" Pubmed 19844255 Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. Pubmed 3.17E-04 1.00E+00 3.14E-02 4.05E-01 11 35 "VAT1L,LDHD,TMEM170A,GABARAPL2,CHST6,BCO1,FA2H,ZFP1,ATMIN,CHST5,GAN" Pubmed 27705803 A High-Density Map for Navigating the Human Polycomb Complexome. Pubmed 3.24E-04 1.00E+00 3.20E-02 4.13E-01 72 495 "PWWP2A,MTA3,MTUS1,OGT,DYNLL1,ATP2A2,ARHGEF7,BTRC,FOXK1,AIFM1,ARHGEF2,ZMYM4,L3MBTL4,KMT2C,FBXO7,ARHGEF6,NSL1,RBM39,PHF19,LIN54,ATN1,DNAJB6,DYRK1A,E2F5,E2F6,PHC2,YAF2,EIF4G1,EZH1,KAT8,MAD2L2,NOP56,DCTN2,SPECC1,OGA,AHDC1,CBX1,KDM2B,EML4,TUBA1C,DIDO1,MSL1,SOWAHA,ZNF678,TUBB2B,KPNA5,GIT1,MXI1,CHAMP1,PDPK1,MAPKAP1,RC3H2,KANSL1,PSMA6,SPDL1,MORC4,FBXO11,KANSL3,TET1,RCOR3,MBD5,SPATA7,MYCBP2,POGZ,GSE1,FBXW11,SIN3B,CBX5,RICTOR,PPP1R3F,LAS1L,SENP7" Pubmed 7760812 Molecular characterization of a novel transcription factor that controls stromelysin expression. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "AXIN2,CALB1,GFAP,MITF,PAX6,PROX1,TCF4,THRA" Pubmed 27870829 Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "EDIL3,TUBB3,RDX,SOX2,CRB1,TJP1,PARD3,CRB2" Pubmed 22424930 Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "SCARB1,CD81,CDH2,NECTIN3,PLXNA4,SIRPA,PDGFRA,ROBO2" Pubmed 23704327 The giant spectrin ?V couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "DYNC1I1,USH1C,EPB41,DCTN2,KIF3A,MYO7A,SPTAN1,SYP" Pubmed 23217170 The transcription factor Uncx4.1 acts in a short window of midbrain dopaminergic neuron differentiation. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "ASCL1,CALB1,CALB2,OLIG2,TUBB3,GAD1,NKX2-2,PAX6" Pubmed 27117402 Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "LDB2,LHX2,PPP1R1B,TBR1,DKK3,FEZF2,RBBP8,ZFPM2" Pubmed 19088125 Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "CALB1,CALB2,NEUROD1,PAX6,PRKCG,PROX1,RLBP1,SLC6A9" Pubmed 24948604 The cortical hem regulates the size and patterning of neocortex. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "NRP2,LHX2,EMX2,GRIK4,SMAD1,SMAD9,PROX1,RORB" Pubmed 27302397 Tcf7l1 protects the anterior neural fold from adopting the neural crest fate. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "AXIN2,CDH2,FOXG1,GBX2,SOX1,SOX2,SOX10,TCF7L2" Pubmed 11322959 "The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number." Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "PCDHB17P,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3" Pubmed 27385012 Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "CALB1,ZEB2,GAD1,GLUL,NEUROD1,PAX6,PROX1,SLC6A9" Pubmed 27633990 Control of lens development by Lhx2-regulated neuroretinal FGFs. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "BMP7,CDH2,LHX2,ETV1,SMAD1,SMAD9,PAX6,PROX1" Pubmed 18547144 Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "SLIT2,DCC,PAX6,ROBO1,ROBO2,SLIT1,ROBO3,CNTN2" Pubmed 1783381 Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "APP,CBS,CP,GAP43,GART,S100B,SST,TF" Pubmed 20660756 Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "AXIN2,BMPR1B,SMAD1,SMAD9,MYCN,PTCH1,TCF4,TCF7L2" Pubmed 21502507 Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Pubmed 3.31E-04 1.00E+00 3.24E-02 4.19E-01 8 20 "AXIN2,PROM1,CDH2,TUBB3,FOXG1,HES5,PAX6,SOX2" Pubmed 27292642 Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and ?-Cell Function. Pubmed 3.47E-04 1.00E+00 3.40E-02 4.39E-01 10 30 "GCK,KCNJ11,NEUROD1,NKX2-2,PAX6,ARX,SNAP25,SST,ABCC8,SYP" Pubmed 20080650 Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. Pubmed 3.47E-04 1.00E+00 3.40E-02 4.39E-01 10 30 "SORCS2,ANK2,KALRN,CREB5,MRVI1,C2orf80,NXPH1,RYR1,PSD3,TUB" Pubmed 26586428 SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "ACLY,MTMR3,LRRFIP1,DMTF1,E2F6,RNPS1,MYH7,NASP,FXR1" Pubmed 17468181 Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "ASCL1,BMP7,EDIL3,EMX2,SMAD1,SMAD9,PAX6,PROX1,PTCH1" Pubmed 8493579 Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "SPTBN4,EGFR,FYN,JAK1,JAK2,NCAM1,PTK2,SPTAN1,SPTB" Pubmed 25843547 Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "NRP2,CDH2,SLIT2,SEMA3D,TUBB3,ROBO1,ROBO2,SLIT1,SOX10" Pubmed 26554594 The MAFB transcription factor impacts islet ?-cell function in rodents and represents a unique signature of primate islet ?-cells. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "ATP2A2,KCNJ11,NEUROD1,NNAT,PAX6,PCSK2,POU3F4,ARX,SST" Pubmed 27518902 HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "NRP2,LYVE1,IGFBPL1,PROX1,SCN7A,MESP1,TNNT1,HIRA,NSD2" Pubmed 16374509 Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "SNX30,ADAM15,ARHGEF7,ARHGEF6,SH3GLB1,SORBS3,SORBS1,FYN,SH3GL2" Pubmed 12724834 Patterning of the lateral ganglionic eminence by the Gsh1 and Gsh2 homeobox genes regulates striatal and olfactory bulb histogenesis and the growth of axons through the basal ganglia. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "ASCL1,NRP2,CALB1,LHX2,TBR1,GAD1,NPY,PAX6,PENK" Pubmed 12397111 Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "ASCL1,LHX2,DLX1,TUBB3,GAD1,GAD2,HES5,MAP2,POU3F4" Pubmed 20589901 Identification of genes controlled by LMX1B in E13.5 mouse limbs. Pubmed 3.57E-04 1.00E+00 3.42E-02 4.41E-01 9 25 "SLITRK1,NRP2,NTM,EYA1,FOXF2,NBL1,PENK,SSTR1,CBLN2" Pubmed 22083510 Oct4 links multiple epigenetic pathways to the pluripotency network. Pubmed 3.65E-04 1.00E+00 3.42E-02 4.41E-01 34 191 "ARID1A,MTA3,TAOK1,OGT,ATP1A1,PTBP2,CNN3,NCOR2,MATR3,DBT,GFAP,TCERG1,GLI2,PRRC2B,TOX2,IDH3B,LIMS1,AFDN,NACA,RCOR2,NUMA1,LAMA1,DPF2,PBRM1,SALL1,SCAF8,TET1,SMARCA4,SMARCC2,SMARCE1,TMPO,TP53BP1,RTN4,JMJD1C" Pubmed 24925909 Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,TUBB3,MITF,RET,SOX10" Pubmed 20427655 CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CNTNAP1,OLIG2,GFAP,MOG,PMP22" Pubmed 14685273 Identification of PKCzetaII: an endogenous inhibitor of cell polarity. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PARD6A,MBP,PKM,PRKCZ,TJP1" Pubmed 18454205 The secreted metalloprotease ADAMTS20 is required for melanoblast survival. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "VCAN,KIT,KITLG,MITF,ADAMTS9" Pubmed 19786558 The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "NCOA1,NCOR1,NCOR2,MED1,RXRA" Pubmed 12134159 CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CRMP1,DPYSL2,DPYSL4,TUBB2A,DPYSL5" Pubmed 17442807 The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,OLIG1,OLIG2,TUBB3,PDGFRA" Pubmed 28299779 The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,NSG2,NSG1,SOX2,SATB2" Pubmed 8951061 Forebrain patterning defects in Small eye mutant mice. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,DLX1,EMX2,PAX6,PROX1" Pubmed 18090917 Patterned neuropathologic events occurring in hyh congenital hydrocephalic mutant mice. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GFAP,MBP,NCAM1,NEFH,S100B" Pubmed 21467208 Ascl1 participates in Cajal-Retzius cell development in the neocortex. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,CALB1,CALB2,PAX6,RELN" Pubmed 10212259 Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CAMK2G,PRKCB,PRKCG,PRKCZ,TIAM1" Pubmed 18371392 Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB2,SLC32A1,TBR1,NTRK2,PAX6" Pubmed 28330839 "Evolutionary insights into T-type Ca(2+) channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CACNA1I,CACNA1G,CACNA1B,CACNA1D,CACNA1E" Pubmed 26487682 Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ATP2A2,MYH6,MYH7,NPPA,TMOD1" Pubmed 16814267 Mice without transcription factor KLF7 provide new insight into olfactory bulb development. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GAD1,GAP43,STMN2,RELN,SYP" Pubmed 9831645 EMX2 protein in the developing mouse brain and olfactory area. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,CALB2,EMX2,GAP43,MAP2" Pubmed 17287360 "Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TMEM108,DCTN1,LAMP2,NTRK2,RAB5B" Pubmed 21664577 Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,BOC,CDON,PAX6,CNTN2" Pubmed 27816769 In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "DLG4,GFAP,MBP,PLP1,SYP" Pubmed 11114196 "Calsarcins, a novel family of sarcomeric calcineurin-binding proteins." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ACTN1,ACTN2,MYOZ2,PPP3CA,PPP3CB" Pubmed 15294144 EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CDH8,LHX2,EMX2,GBX2,PAX6" Pubmed 24122442 Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "RAB39B,GRIA1,LMO1,PAX6,ARX" Pubmed 21613606 Similar effects of all WNK3 variants on SLC12 cotransporters. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SLC12A5,SLC12A6,SLC12A2,SLC12A4,WNK3" Pubmed 22265416 Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "OLIG2,GLI2,NKX2-2,PAX6,PTCH1" Pubmed 20237162 "Chemerin, a novel adipokine in the regulation of angiogenesis." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PI16,EDIL3,GRM8,TRHDE,PTCH1" Pubmed 23308235 Kif14 mutation causes severe brain malformation and hypomyelination. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,OLIG2,MAG,MBP,PDGFRA" Pubmed 11821434 The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PKP4,CDH2,CTNND1,CTNND2,ERBIN" Pubmed 8163463 Transmembrane topology of the glutamate receptor subunit GluR6. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GRIA1,GRIA4,GRIK1,GRIK2,GRIK3" Pubmed 21768377 "G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,ADGRG1,TUBB3,TBR1,RELN" Pubmed 19914172 KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "KIF26A,TUBB3,KIT,MAPK3,UCHL1" Pubmed 22898830 "Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB2,GFAP,MAP2,RELN,DICER1" Pubmed 26546974 "Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ELAVL3,ELAVL4,SOX8,SOX10,TMEM163" Pubmed 18479186 Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "UNC5A,DCC,GBX2,L1CAM,UNC5B" Pubmed 21106831 "Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "APP,GRIN3A,GRIN1,GRIN2C,GRIN2D" Pubmed 12692556 The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ARHGDIA,ARHGEF1,MAG,OMG,RTN4" Pubmed 28467410 Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,TBR1,MAP2,PAX6,PPP4R3A" Pubmed 22689348 Hes1 is required for the development of the superior cervical ganglion of sympathetic trunk and the carotid body. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CHGA,FABP7,TUBB3,S100B,UCHL1" Pubmed 9651375 GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GRM1,GRM2,GRM5,RGS12,PLCB1" Pubmed 19372219 Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ADRB2,ARRB1,ARRB2,RACK1,PDE4D" Pubmed 23415800 Making sense of Dlx1 antisense RNA. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "DLX1,OLIG2,GAD1,SST,TMEM163" Pubmed 16603319 Expression of discoidin domain receptor 1 during mouse brain development follows the progress of myelination. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "APC,DDR1,GFAP,CNDP1,MBP" Pubmed 10547923 A QTL for the genetic variance in free-running period and level of locomotor activity between inbred strains of mice. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "KCNJ10,NHLH1,DDR2,RXRG,VANGL2" Pubmed 11748155 The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,TBR1,GLI2,PDGFRA,PTCH1" Pubmed 17604700 Expression of LHX3 and SOX2 during mouse inner ear development. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,MYO6,MYO7A,PROX1,SOX2" Pubmed 18638478 Consequence of the loss of Sox2 in the developing brain of the mouse. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,HES5,MAP2,SOX2,SOX3" Pubmed 16336945 "Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "OLIG1,MBP,PDGFRA,PLP1,SOX10" Pubmed 16618118 Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CSNK1E,CSNK1G3,MAPT,SNCA,DBNDD2" Pubmed 23213374 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "DCTN1,CEP170,CNTRL,KIF2A,ODF2" Pubmed 20070850 Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CCAR2,BRINP1,PLEKHM1,MAPT,SNCA" Pubmed 22006950 Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EPB41L5,TJP2,EPB41L4B,TJP1,PARD3" Pubmed 22056988 Nuclear PKM2 regulates ?-catenin transactivation upon EGFR activation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "AXIN2,APC,EGFR,PKM,TCF7L2" Pubmed 18287202 Ascl1 is required for oligodendrocyte development in the spinal cord. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,OLIG2,MAG,MBP,NKX2-2" Pubmed 25960350 Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CDH2,GFAP,NFIA,NFIX,SOX3" Pubmed 14622145 "Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SCRG1,SNAP25,SYT1,SYT5,SCG2" Pubmed 17507397 Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ETV1,MAP2,NEUROD1,RELN,CUX2" Pubmed 15964829 Generation and characterization of Rac3 knockout mice. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,GAD1,GAD2,MAP2,SYN1" Pubmed 24993945 A crucial role for polysialic acid in developmental interneuron migration and the establishment of interneuron densities in the mouse prefrontal cortex. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,GAD1,NCAM1,SST,ST8SIA2" Pubmed 16565076 New insights into BS69 functions. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "E2F6,EZH1,ZMYND11,SMARCA4,ZMYND8" Pubmed 23416450 EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EGFR,MAP2,NTRK2,NTRK3,PAX6" Pubmed 24766809 "Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,TBR1,GFAP,NEFH,PAX6" Pubmed 24771490 A novel cell migratory zone in the developing hippocampal formation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ELAVL2,EPHB1,NEUROD1,PROX1,SOX2" Pubmed 25527292 Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,TOX,TUBB3,SOX2,SATB2" Pubmed 24744148 Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "STXBP5,STX1B,SNAP25,STX1A,SYT1" Pubmed 20028935 "EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EDN1,EDN3,EDNRA,EDNRB,NOS1" Pubmed 24198279 Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ELAVL3,ELAVL4,LAMA1,SOX1,SOX10" Pubmed 15152034 Cholecystokinin modulates migration of gonadotropin-releasing hormone-1 neurons. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CCK,CCKBR,TUBB3,NCAM1,PRPH" Pubmed 22855790 Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SYT17,KCNH1,KCNH2,KCNJ3,PTCH1" Pubmed 19185337 Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB2,EPB41,TUBB3,ELP5,TUBA1A" Pubmed 12526740 Reelin activates SRC family tyrosine kinases in neurons. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "FYN,RELN,PTK2,VLDLR,LRP8" Pubmed 17360663 HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "DLG4,GRIN1,GRIN2C,GRIN2D,NOS1" Pubmed 24618891 Genome-wide association study reveals two new risk loci for bipolar disorder. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ADCY2,ANK3,TENM4,NCAN,POU3F2" Pubmed 19666824 Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CDH2,MITF,PAX6,PROX1,SOX2" Pubmed 17301033 Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PRKAG2,FOXO3,PPARGC1A,MAPK8,MAPK9" Pubmed 17923693 "Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CAMK2A,AKAP6,PDE4DIP,SYNPO,SYNPO2" Pubmed 17596436 A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,CALB2,DLX1,TBR1,GAD1" Pubmed 28515211 Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and Testes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EGR3,GFRA1,SOX1,SOX2,SOX3" Pubmed 27277803 Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PDE8B,CRHBP,MEF2C,HCN1,SGK1" Pubmed 18417704 Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SLIT2,GAP43,ROBO1,ROBO2,SLIT1" Pubmed 15834155 "Kinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "AMPH,DNM1,DNM2,ITSN1,SH3GL2" Pubmed 24803543 Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to ?-motoneurons and altered during motoneuron diseases. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SLC32A1,ERBB2,ERBB4,SLC17A7,SLC17A6" Pubmed 20516201 Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "OLIG2,GLI2,NKX2-2,PTCH1,ARX" Pubmed 26245956 Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "APC,OLIG2,KCNC2,L1CAM,MAP2" Pubmed 12351654 Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CASK,DLG2,DLG3,MPP6,MPP2" Pubmed 7983158 Structural diversity of band 4.1 superfamily members. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EPB41L5,EPB41,EPB41L1,EPB41L2,EPB41L3" Pubmed 24739528 Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB2,DCC,GFAP,L1CAM,SATB2" Pubmed 16691566 Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ACHE,CALB1,ETV1,PPP1R1B,L1CAM" Pubmed 19515977 Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SLIT2,EPHB1,GFAP,L1CAM,RGS3" Pubmed 7615634 "Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "AMH,ANK1,ANK3,KITLG,PAH" Pubmed 24086156 In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "LRIG1,MYO7A,NEFH,SOX2,SYP" Pubmed 17448763 Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "KIT,NOS1,TAC1,TAC3,TACR1" Pubmed 12203721 Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "PARD6A,AFDN,PRKCZ,TJP1,PARD3" Pubmed 19619645 Tissue-specific requirements for FGF8 during early inner ear development. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,MYO7A,NEUROD1,PROX1,MESP1" Pubmed 24393035 The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SLC12A5,SLC12A6,CAB39,SLC12A4,WNK1" Pubmed 16267237 Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CDH2,PARD6A,AFDN,PRKCZ,PARD3" Pubmed 27510895 Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,KIAA0319,EDIL3,NEFH,PAX6" Pubmed 23100420 "Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,FABP7,GFAP,PAX6,RBFOX2" Pubmed 22691363 Tenascin C regulates proliferation and differentiation processes during embryonic retinogenesis and modulates the de-differentiation capacity of Müller glia by influencing growth factor responsiveness and the extracellular matrix compartment. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ASCL1,TUBB3,GLUL,PAX6,PTPRZ1" Pubmed 15253893 The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ATP1A1,ATP1A2,ATP1A3,ATP2A2,SLC8A1" Pubmed 18602463 Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "EGFR,SH3KBP1,ATXN2,SH3GL2,SH3GL3" Pubmed 16135819 The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "DUSP9,MAPK3,MAPK7,MAPK8,MAPK9" Pubmed 15541311 GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ACHE,GAP43,GFRA1,RET,SOX10" Pubmed 22253716 Bmp7 functions via a polarity mechanism to promote cloacal septation. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "BMP7,SMAD1,SMAD9,MAPK8,MAPK9" Pubmed 8175718 gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GABRA1,GABRA2,GABRA3,GABRA4,GABRB3" Pubmed 10380922 Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "CALB1,MAP2,RELN,VLDLR,LRP8" Pubmed 18334916 "Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ABAT,GPHN,GABRA3,GABRA4,SLC6A11" Pubmed 19935654 Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "OLIG2,MBP,NEFH,NRDC,PDGFRA" Pubmed 23246003 Mutations in the ?-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,TUBB4A,TUBB2B,TUBB2A,TUBB1" Pubmed 11528422 GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "GABRA1,GABRA2,GABRA3,GABRB1,GABRB3" Pubmed 19683723 "Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ATP1A1,ATP1A2,ATP1A3,FXYD1,SLC8A1" Pubmed 20418906 Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,RBPJ,HES5,PTCH1,SOX2" Pubmed 12809483 ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ACTN2,ZFYVE9,RACK1,LRP12,ST7" Pubmed 8738414 Synaptobrevin is essential for secretion but not for the development of synaptic processes. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "SV2B,SV2A,SNAP25,SYP,SYT1" Pubmed 16316992 Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "MAGI1,MAGI2,DLG4,MAGI3,GOPC" Pubmed 20006658 "Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice." Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "NRP2,CALB1,SEMA3B,SLC17A7,SLC17A6" Pubmed 10951186 Gene knockout studies of Ca2+-transporting ATPases. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP2C1" Pubmed 25218921 Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. Pubmed 3.69E-04 1.00E+00 3.42E-02 4.41E-01 5 8 "TUBB3,MYO6,GPSM2,ANKRD6,VANGL2" Pubmed 15533830 Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Pubmed 3.83E-04 1.00E+00 3.42E-02 4.41E-01 13 47 "NR0B1,AMH,CBLN1,SCARB1,QKI,COL9A3,DTNA,MRO,EMX2,PDGFRA,SERPINE2,ZFPM2,HHIP" Pubmed 27510977 Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Pubmed 3.83E-04 1.00E+00 3.42E-02 4.41E-01 13 47 "AXIN2,LGR5,NUMB,DCLK1,CHGA,HEYL,RBPJ,HES5,MSI1,SMARCA4,TCF4,TCF7L2,FZD3" Pubmed 12578829 "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2." Pubmed 3.84E-04 1.00E+00 3.42E-02 4.41E-01 15 59 "RAB29,RAB3C,RAB33A,RAB28,RAB26,RIMS2,RAB39B,RAB9B,RAB30,RAB40B,RAB39A,RAB3A,RAB5B,RPH3A,RIMS1" Pubmed 22053931 Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. Pubmed 3.85E-04 1.00E+00 3.42E-02 4.41E-01 18 78 "CDC42,RBM39,MATR3,SYNCRIP,DCTN2,GLUL,MTR,NACA,NASP,PCMT1,PSAT1,PSMA6,PNMA8A,RPS20,CDK5RAP3,SPART,UBC,AMOT" Pubmed 28611094 Agonist-specific protein interactomes of glucocorticoid and androgen receptor as revealed by proximity mapping. Pubmed 3.85E-04 1.00E+00 3.42E-02 4.41E-01 18 78 "DPF1,ARID1A,NCOA1,NCOR1,NCOR2,DBT,ZNF512,NR3C1,MED1,DPF2,SMARCA4,SMARCC2,SMARCE1,RBM34,POGZ,GSE1,RBFOX2,JMJD1C" Pubmed 23284306 A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. Pubmed 4.00E-04 1.00E+00 3.42E-02 4.41E-01 22 105 "SACS,DPP6,EGFR,STX2,ETV1,NELFCD,DOT1L,ARPP21,ADAM28,PACRG,MIA2,MYBPC1,PURG,IRX1,PKIA,PTX3,C12orf49,DZIP1,PSD3,STXBP4,USP1,LGI4" Pubmed 27093085 Calmodulin Promotes N-BAR Domain-Mediated Membrane Constriction and Endocytosis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AMPH,BIN1,CALM1,SH3GL2" Pubmed 10972938 Synapse formation during neuron differentiation: an in situ study of the myenteric plexus during murine embryonic life. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ENO2,RET,SNAP25,SYP" Pubmed 24554721 Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "BSN,GPHN,GABRA2,MAP2" Pubmed 18086889 The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ARID1A,NR3C1,SMARCA4,SMARCC2" Pubmed 19966779 Enhanced tonic GABAA inhibition in typical absence epilepsy. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1A,CACNB4,CACNG2,SLC6A1" Pubmed 14559911 Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ATP1A1,DLG4,KCNA4,KCND2" Pubmed 15878769 Mash1 is required for glomus cell formation in the mouse carotid body. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ASCL1,TUBB3,GFAP,UCHL1" Pubmed 12223541 The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACTN1,CDK5R1,CDK5R2,CAMK2A" Pubmed 15617678 Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB2,FABP7,MAP2,RELN" Pubmed 11877424 Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AMPH,DNM1,DYRK1A,SH3GL2" Pubmed 23500099 Immunocytochemical identification of electroneutral Na?-coupled HCO?? transporters in freshly dissociated mouse medullary raphé neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLC4A7,SLC4A8,GAD2,SLC4A10" Pubmed 9129177 Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,SLC1A2,SLC1A3,SLC1A6" Pubmed 12209604 "Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "INA,ELAVL3,ELAVL4,NACA" Pubmed 27170659 Deletion of novel protein TMEM35 alters stress-related functions and impairs long-term memory in mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,DLG4,TMEM35A,GRIA1" Pubmed 26975582 Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CLTA,CLTB,CLTC,EPN1" Pubmed 15682390 Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EGFR,ERBB2,ERBB4,GAD1" Pubmed 16436603 Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 27991901 Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLC32A1,GAD1,SCN7A,SLC17A6" Pubmed 10900017 The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "BSN,GPHN,GABRG2,GABARAPL2" Pubmed 20805473 Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CNIH2,CNIH3,CACNG2,GRIA1" Pubmed 15563604 Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactions. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APBA2,SYTL4,STX1A,STXBP1" Pubmed 10626068 Endothelin in the central control of cardiovascular and respiratory functions. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 14704270 Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AMPH,SYNJ1,SH3GLB1,PPP3CA" Pubmed 26245976 Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KIF3A,PKD1,VANGL2,IFT88" Pubmed 22178608 Spatio-temporal expression analysis of the calcium-binding protein calumenin in the rodent brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,DLG4,GFAP,NCAM1" Pubmed 23136391 Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "LHX2,GBX2,ROBO1,ROBO2" Pubmed 26954557 Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DCTN1,KIF5C,KIFC3,KIF1B" Pubmed 20427320 The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CLTA,CLTB,CLTC,TF" Pubmed 12871946 "Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,RIMS2,RPH3A,RIMS1" Pubmed 17785183 alpha2-Chimaerin is an essential EphA4 effector in the assembly of neuronal locomotor circuits. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CHN1,CHN2,SIPA1L1,EPHB1" Pubmed 10022198 Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GABRA2,GABRB3,GAD1,NPY" Pubmed 21454491 "Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NCOA1,HEYL,HEY1,HEY2" Pubmed 20639532 A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CPEB2,EGFR,CPEB3,CPEB4" Pubmed 10864954 Slit2 is a repellent for retinal ganglion cell axons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 17494763 ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CD320,RELN,VLDLR,LRP8" Pubmed 9615221 Physical and genetic maps of the deafwaddler region on distal mouse Chr 6. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ATP2B2,CNTN3,SLC6A11,SYN2" Pubmed 12773624 Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB2,TUBB3,FOXG1,RELN" Pubmed 14505571 Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ARHGEF7,CDC42,EGFR,PAK3" Pubmed 15035981 A small modulatory dsRNA specifies the fate of adult neural stem cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "STMN2,GRM2,SMARCA4,SMARCC2" Pubmed 12093152 Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "STX1B,STX1A,STXBP1,VAMP1" Pubmed 9808460 SAP90 binds and clusters kainate receptors causing incomplete desensitization. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DLG3,DLG4,GRIK2,GRIK5" Pubmed 17436251 Mutations in cytokine receptor-like factor 1 (CRLF1) account for both Crisponi and cold-induced sweating syndromes. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CRLF1,CNTFR,IL6ST,LIFR" Pubmed 17215451 BAD-LAMP defines a subset of early endocytic organelles in subpopulations of cortical projection neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ETV1,MAP2,CUX2,LAMP5" Pubmed 8982507 Characterization of endothelin receptors in the human umbilical artery and vein. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 15597051 Mice lacking IGF-I and LIF have motoneuron deficits in brain stem nuclei. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,CALB2,GFAP,IGF1" Pubmed 22764252 Lack of molecular-anatomical evidence for GABAergic influence on axon initial segment of cerebellar Purkinje cells by the pinceau formation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "BSN,SLC32A1,GABRA1,GAD1" Pubmed 15141162 Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PROM1,TUBB3,ANLN,PARD3" Pubmed 28426968 MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ANK3,TUBB3,MAP2,TRIM46" Pubmed 18444252 Neurotransmission and bipolar disorder: a systematic family-based association study. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GRIA1,GRIN2C,GRIN2D,QDPR" Pubmed 9723620 Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AP2A1,AP2A2,EPS15L1,EPN1" Pubmed 23912123 DBZ (DISC1-binding zinc finger protein)-deficient mice display abnormalities in basket cells in the somatosensory cortices. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB2,GAD1,ZNF365,SST" Pubmed 15207848 Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 17722031 Differential expression of phosphacan/RPTPbeta isoforms in the developing mouse visual system. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CNTN1,L1CAM,PTPRZ1,CNTN2" Pubmed 15682394 The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,DLX1,GAD1,ARX" Pubmed 19136967 Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RCAN1,RCAN2,PPP3CB,TAB2" Pubmed 18829436 Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NCOR1,GFAP,NCAM1,SIRT1" Pubmed 28512739 Normal development of spinal axons in early embryo stages and posterior locomotor function is independent of GAL-1. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PLXNA4,TUBB3,GFAP,PRPH" Pubmed 10430869 Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AP2A2,BIN1,SNAP91,DNM1" Pubmed 10428084 Subunit composition of Kv1 channels in human CNS. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KCNAB2,KCNA1,KCNA2,KCNA4" Pubmed 27635635 An alternative splicing program promotes adipose tissue thermogenesis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NOVA1,NOVA2,MAPK8,MAPK9" Pubmed 15459722 Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SNPH,SYBU,SNAP25,STX1A" Pubmed 10194519 "Gene expression of vasoactive intestinal contractor/endothelin-2 in ovary, uterus and embryo: comprehensive gene expression profiles of the endothelin ligand-receptor system revealed by semi-quantitative reverse transcription-polymerase chain reaction analysis in adult mouse tissues and during late embryonic development." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 9620692 Oligodendrocyte population dynamics and the role of PDGF in vivo. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GALC,MBP,PDGFRA,PLP1" Pubmed 9009191 Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACTN2,CALM1,DLG4,GRIN1" Pubmed 21200028 "Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,SDC3,TUBB3,PTN" Pubmed 23358160 Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ARNTL,SNX29,CTNNA3,ZEB1" Pubmed 27769864 HMGB1 induces human non-small cell lung cancer cell motility by activating integrin ?v?3/FAK through TLR4/NF-?B signaling pathway. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "HMGB1,ITGAV,PTK2,TLR4" Pubmed 15317815 PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MAGI1,ASIC3,DLG4,GOPC" Pubmed 19671701 Alpha-kinase anchoring protein alphaKAP interacts with SERCA2A to spatially position Ca2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ATP2A2,CAMK2A,CAMK2D,CAMK2G" Pubmed 22683750 A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EMX2,KCND3,SEC14L1,MGAT5B" Pubmed 15665106 Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACTN1,ACTN2,MYOZ2,PPP3CA" Pubmed 21262840 The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ADGRB3,C1QL2,C1QL1,C1QL4" Pubmed 8100981 Levels of somatostatin and cholecystokinin in the brain of ataxic mutant mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1A,CCK,SST,AGTPBP1" Pubmed 7877445 Genomic structure and mapping of precerebellin and a precerebellin-related gene. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CBLN1,DCC,MBP,CBLN2" Pubmed 15558732 "Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,CALB2,CDH8,SLC6A1" Pubmed 28974418 MGE-derived nNOS(+) interneurons promote fear acquisition in nNOS(-/-) mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "FOXG1,MEIS2,NOS1,PAX6" Pubmed 23776487 Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GFAP,NFIX,PROX1,SLC1A3" Pubmed 16606358 Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DLG4,SHANK1,GRIA1,SHANK2" Pubmed 28780049 Netrin1 establishes multiple boundaries for axon growth in the developing spinal cord. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "OLIG2,SOX2,ROBO3,CNTN2" Pubmed 11296258 Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1A,CACNA1B,CACNA1D,CACNA1E" Pubmed 19558451 Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GABBR1,KCNJ3,KCNJ5,KCNJ9" Pubmed 10996085 Synapse formation: if it looks like a duck and quacks like a duck .... Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NLGN4X,NLGN3,NLGN4Y,NLGN1" Pubmed 12504591 The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CDC42,SHANK1,BAIAP2,SHANK2" Pubmed 12202822 "SynCAM, a synaptic adhesion molecule that drives synapse assembly." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CASK,NLGN1,SYP,CADM1" Pubmed 15184042 Evidence showing an intermolecular interaction between KChIP proteins and Taiwan cobra cardiotoxins. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KCND2,KCNIP3,KCNIP2,KCNIP1" Pubmed 25232121 Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MYO6,SOX2,HEY1,HEY2" Pubmed 20664520 "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ADCY2,ARRB2,AKAP5,PDE4D" Pubmed 9403476 Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MAPK3,MAPK8,MAPK9,MAPK10" Pubmed 11013247 Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 1717158 RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GRIA2,GRIA4,GRIK1,GRIK2" Pubmed 7894155 High-resolution genetic map and YAC contig around the mouse neurological locus reeler. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA2D1,DPP6,EN2,RELN" Pubmed 26077106 Generation of BAF53b-Cre transgenic mice with pan-neuronal Cre activities. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,ACTL6B,GFAP,MBP" Pubmed 20231428 Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "LMO2,TAL1,TCF4,HEY1" Pubmed 11160423 Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "LRRC7,CAMK2A,CAMK2B,CAMK2G" Pubmed 19193724 "Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br/+ adult mice." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ATP1A1,EDN1,EDNRA,EDNRB" Pubmed 23728480 In vivo assembly of the axon initial segment in motor neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ANK3,SPTBN4,SPTAN1,NFASC" Pubmed 10766765 "Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ST8SIA3,NCAM1,ST8SIA1,ST8SIA2" Pubmed 17113391 Role of CLASP2 in microtubule stabilization and the regulation of persistent motility. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APC,CLIP1,CLASP2,CLASP1" Pubmed 25176044 Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SV2A,TUBB3,S100B,SOX10" Pubmed 12011466 The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APP,NUMB,NUMBL,NBL1" Pubmed 15843399 Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDNRB,ATP8A1,SOX10,UCHL1" Pubmed 10725395 The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DLG2,DLG3,DLG4,ERBB4" Pubmed 16908628 An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "OLIG2,MBP,PDGFRA,PLP1" Pubmed 17306257 "Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DBNL,SH3KBP1,SH3BP2,VAV1" Pubmed 16292983 "Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ANK2,ATP1A1,ATP1A2,SLC8A1" Pubmed 15620359 Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NLGN4X,NRXN1,NLGN3,NLGN1" Pubmed 15451373 Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1A,CACNA1B,CACNA1D,CACNA1E" Pubmed 7568894 The molecular basis of the neuropathies of mouse and human. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MAG,MBP,PLP1,PMP22" Pubmed 15964665 P2X(7) receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GFAP,GLUL,MAP2,P2RX7" Pubmed 9238017 The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SYNJ1,DNM1,SH3GL2,SH3GL3" Pubmed 8699246 Structure and evolution of neurexophilin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NRXN1,NXPH3,NXPH2,NXPH1" Pubmed 18425115 Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACTN1,ACTN2,CALB1,CALB2" Pubmed 10394361 Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MAPK8,S100B,VAV1,VAV2" Pubmed 26290247 Netrin1-DCC-Mediated Attraction Guides Post-Crossing Commissural Axons in the Hindbrain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DCC,TUBB3,ROBO1,ROBO2" Pubmed 21139978 "HuB/C/D, nPTB, REST4, and miR-124 regulators of neuronal cell identity are also utilized in the lens." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PTBP2,ELAVL2,ELAVL3,ELAVL4" Pubmed 10842075 "Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,SLIT2,ROBO1,ROBO2" Pubmed 26506308 Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AMPH,BIN1,CLIP1,SYNE2" Pubmed 23903657 Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APC,LGR5,ROBO1,ROBO2" Pubmed 8548579 Regulation of retinoblastoma gene expression in a mouse mammary tumor model. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN3,EDNRA,EDNRB,PRPH" Pubmed 28234971 Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 24802752 The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR). Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CNTFR,IL6R,IL6ST,LIFR" Pubmed 10436028 Characterization of a fourth adaptor-related protein complex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AP4M1,AP4B1,AP4S1,AP4E1" Pubmed 20386732 Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "VAX2,L1CAM,DICER1,ZIC2" Pubmed 19926856 The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NRXN1,F8,NLGN1,SYP" Pubmed 14550776 "Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "HAPLN1,HAPLN2,NEFH,BCAN" Pubmed 19357271 Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APP,DLG4,MAP2,SYP" Pubmed 28041903 Exosomal MicroRNA Transport from Salivary Mesenchyme Regulates Epithelial Progenitor Expansion during Organogenesis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NUMB,NUMBL,FOXG1,IFT88" Pubmed 15372074 TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GFAP,MAP2,MBP,NTRK2" Pubmed 22772332 Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB2,ROBO1,ROBO2,SLIT1" Pubmed 21976236 "The usefulness of S100B, NSE, GFAP, NF-H, secretagogin and Hsp70 as a predictive biomarker of outcome in children with traumatic brain injury." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ENO2,GFAP,NEFH,S100B" Pubmed 21209221 Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 19213956 Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,KCNC1,KCND2,KCND3" Pubmed 17921328 "Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ADORA1,ADORA2A,ADORA3,PLCB2" Pubmed 27629715 Soluble Conformers of A? and Tau Alter Selective Proteins Governing Axonal Transport. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "FGF14,KIF5A,KLC1,MAPT" Pubmed 3839797 Five mouse tubulin isotypes and their regulated expression during development. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBA1B,TUBB4A,TUBB2A,TUBA1A" Pubmed 23261870 Differential maturation of GIRK2-expressing neurons in the mouse cerebellum. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GAD1,GRM2,GRM3,PAX6" Pubmed 10399933 Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,TUBB3,RELN,CNTN2" Pubmed 22948383 Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NLGN4X,NRXN1,CNTNAP2,CTNNA3" Pubmed 9284755 Endothelin-1 and ETA receptor expression in vascular smooth muscle cells from human placenta: a new ETA receptor messenger ribonucleic acid is generated by alternative splicing of exon 3. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 21849472 Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TMEM108,APPL1,NTRK2,SH3GL2" Pubmed 9753148 Prenatal differentiation of mouse vomeronasal neurones. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,GAP43,CNDP1,UCHL1" Pubmed 18562329 Characterization of the HeCo mutant mouse: a new model of subcortical band heterotopia associated with seizures and behavioral deficits. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EML1,TBR1,SLC1A3,CUX2" Pubmed 12060068 Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1G,CACNA1D,CACNA1E,KIT" Pubmed 18565740 Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "FGF13,L1CAM,RET,SOX10" Pubmed 22253765 Distinct expression/function of potassium and chloride channels contributes to the diverse volume regulation in cortical astrocytes of GFAP/EGFP mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GFAP,KCNJ10,KCNK2,KCNK3" Pubmed 12609596 Slit and robo: expression patterns in lung development. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 21472480 TAK1 expression in the cochlea: a specific marker for adult supporting cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,MYO7A,PROX1,SOX2" Pubmed 15073037 C/EBPalpha deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CSF1R,CSF2RA,IL6R,IL6ST" Pubmed 14659090 Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN3,EDNRB,TUBB3,RET" Pubmed 18053187 Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,FABP7,MAPT,PAX6" Pubmed 10639171 Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,CALB2,NEUROD1,PROX1" Pubmed 19917775 The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RACK1,FYN,GNG2,PTK2" Pubmed 12700241 "Phosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowth." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CNTN1,L1CAM,PTPRB,PTPRZ1" Pubmed 18849981 KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MADD,KIF1A,RAB3A,KIF1B" Pubmed 9495516 Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDNRA,EDNRB,SPP1" Pubmed 11290329 Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CLIP1,CLASP2,CLASP1,CLIP2" Pubmed 12519779 Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PRKCB,PRKCG,STX1A,STXBP1" Pubmed 18925875 mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MAPKAP1,SGK1,MLST8,RICTOR" Pubmed 15207726 Myogenic repressor I-mfa interferes with the function of Zic family proteins. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MDFI,ZIC1,ZIC2,ZIC3" Pubmed 23902858 Neuropilin2 regulates the guidance of post-crossing spinal commissural axons in a subtype-specific manner. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NRP2,GAD2,CNTN2,SEMA3B" Pubmed 8703126 Close linkage of three neuronal genes on distal mouse chromosome 15. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CNTN1,SLC11A2,PRPH,SCN8A" Pubmed 15579137 Myelination triggers local loss of axonal CNR/protocadherin alpha family protein expression. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GAP43,L1CAM,MAG,MBP" Pubmed 18218981 Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2A,CAMK2B,CAMK2D,CAMK2G" Pubmed 11404425 Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ADORA2A,CNR1,DRD1,GNAL" Pubmed 22886731 Expression of nuclear factor one A and -B in the olfactory bulb. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,GAD1,GFAP,NFIA" Pubmed 20884879 RGS6/G?5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RGS6,KCNJ3,KCNJ5,RGS7BP" Pubmed 11830569 Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "OLIG2,MBP,NKX2-2,PDGFRA" Pubmed 21559374 Presenilin/?-secretase regulates neurexin processing at synapses. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CDH2,NRXN1,DLG4,SYP" Pubmed 17009072 Mutations and polymorphisms of Hirschsprung disease candidate genes in Thai patients. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN3,EDNRB,RET,SOX10" Pubmed 12730201 Ca2+-dependent phosphorylation of syntaxin-1A by the death-associated protein (DAP) kinase regulates its interaction with Munc18. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DAPK1,SNAP25,STX1A,STXBP1" Pubmed 22554477 Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "LRIG1,EGFR,ERBB2,ERBB4" Pubmed 29632360 Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CDH8,JAM2,AFDN,SLC17A6" Pubmed 2277065 Developmental regulation of myosin gene expression in mouse cardiac muscle. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "MYH3,MYH6,MYH7,MYL3" Pubmed 21589880 Oligodendrocytes as regulators of neuronal networks during early postnatal development. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,GRIA2,GRIN1,SYP" Pubmed 19855010 Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APC,OLIG1,OLIG2,MAG" Pubmed 11398101 Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CAMK2G,USH1C,MYO7A,PCDH15" Pubmed 14630787 "Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ZNF521,EBF1,SMAD1,ZNF423" Pubmed 12573530 Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GRIA1,GRIA2,GRIK2,GRIK5" Pubmed 18981235 Semaphorin 4D regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,SEMA4D,NCAM1,PLXNB1" Pubmed 11160397 The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ASCL1,HEYL,HEY1,HEY2" Pubmed 25752299 Polysialic acid on SynCAM 1 in NG2 cells and on neuropilin-2 in microglia is confined to intracellular pools that are rapidly depleted upon stimulation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NRP2,NCAM1,CADM1,ST8SIA2" Pubmed 17011503 "Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NCOA1,PPARGC1A,MED1,PDIA2" Pubmed 8587354 Gene expression of endothelin isoforms and receptors in endothelin-1 knockout mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Pubmed 7916325 Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PCSK2,SNAP25,PLCB1,SLC30A4" Pubmed 12403814 Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GFAP,MYO5A,NEFH,PRPH" Pubmed 12200427 Action of complexin on SNARE complex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CPLX2,CPLX1,SNAP25,STX1A" Pubmed 18197264 Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ETV1,PAX6,POU3F2,RELN" Pubmed 27662084 Central Control Circuit for Context-Dependent Micturition. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLC32A1,GAD1,GAD2,SLC17A6" Pubmed 15024750 Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DLGAP2,DLGAP1,DLGAP3,DLG4" Pubmed 21750526 Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KIF5C,KLC1,MAPK8IP3,KLC2" Pubmed 9039914 Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GABRA1,GABRA2,GABRB1,GABRB3" Pubmed 11748139 Slit proteins are not dominant chemorepellents for olfactory tract and spinal motor axons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 9395480 "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APBA2,SNAP25,STX1A,STXBP1" Pubmed 11374908 Isolation of novel heart-specific genes using the BodyMap database. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "HHATL,PDE4DIP,KCNH2,PFKFB2" Pubmed 19013515 "The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PPFIA4,PPFIA2,PPFIA1,PPFIA3" Pubmed 15504324 Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,CHL1,MAP2,RELN" Pubmed 16412618 Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DCT,EDNRB,MITF,SOX10" Pubmed 11520671 Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 20392936 Cholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CCKBR,PRKCB,PRKCG,PLCB1" Pubmed 9126746 An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ASCL1,CHGA,ENO2,SYP" Pubmed 16452688 Layer positioning of late-born cortical interneurons is dependent on Reelin but not p35 signaling. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,CALB2,NOS1,RELN" Pubmed 15458844 The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PICK1,DLG4,RGS3,PDZRN3" Pubmed 15973681 "Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,CALB2,CDH8,TBR1" Pubmed 28464250 Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KCNH2,KCNJ3,KCNJ5,KCNJ11" Pubmed 15255972 Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,MAP2,RELN,SYN1" Pubmed 21652625 "Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DYNC1I1,PDE4A,PDE4B,PDE4D" Pubmed 19557857 De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SNAP25,STX1A,STXBP1,SYT1" Pubmed 21871565 Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,TUBB3,TMEM163,PDSS2" Pubmed 10548550 Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SGK2,PDPK1,SGK1,SGK3" Pubmed 17532644 Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GABBR1,KLC1,JAKMIP1,KIF1B" Pubmed 23691221 ?-Catenin is critical for cerebellar foliation and lamination. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB1,FABP7,GFAP,CNTN2" Pubmed 18586123 Transcriptional repression by leukaemia-associated ETO family members can be independent of oligomerization and coexpressed hSIN3B and N-CoR. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RUNX1T1,CBFA2T2,NCOR1,SIN3B" Pubmed 21296049 Mitochondria-cytoskeleton interaction: distribution of ?-tubulins in cardiomyocytes and HL-1 cells. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "TUBB3,TUBB4A,TUBB2B,TUBB2A" Pubmed 15345594 The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "FYN,SH3BP2,VAV1,VAV2" Pubmed 9482932 "Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GRIA1,GRIA2,GRIA4,NCAM1" Pubmed 22689652 GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "GPR158,RGS11,RGS6,RGS7" Pubmed 15659226 "Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "STXBP5,STX1B,STX1A,STXBP1" Pubmed 24014171 Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AQP4,DMD,DTNA,KCNJ10" Pubmed 9716537 Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "VCAN,NCAN,MAP2,RELN" Pubmed 28450540 "APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "APLP1,APP,DLG4,SYP" Pubmed 7926018 Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "KCNJ3,KCNJ4,KCNJ5,KCNJ9" Pubmed 18854318 "C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "BRSK2,STRADA,BRSK1,CAB39" Pubmed 18558633 Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ALS2,TUBB3,GFAP,NEFH" Pubmed 14729956 Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EDNRB,NEFH,MYCBP2,SYP" Pubmed 10976052 Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "STMN2,NEUROD1,HES6,SOX10" Pubmed 12954717 On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 16885222 Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CALB2,SLIT2,TUBB3,SLIT1" Pubmed 11640898 Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "OLIG1,OLIG2,STMN2,PDGFRA" Pubmed 12695511 Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SNCAIP,SEPT4,SNCB,SNCA" Pubmed 21618221 Analyses of the spatiotemporal expression and subcellular localization of liprin-? proteins. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PPFIA2,PPFIA1,PPFIA3,SYN1" Pubmed 25788872 Non-cell autonomous and non-catalytic activities of ATX in the developing brain. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ENPP2,PTK2,TJP1,PARD3" Pubmed 21118670 Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLIT2,ROBO1,ROBO2,SLIT1" Pubmed 21335558 Collagen I induces discoidin domain receptor (DDR) 1 expression through DDR2 and a JAK2-ERK1/2-mediated mechanism in primary human lung fibroblasts. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "DDR1,JAK2,DDR2,MAPK3" Pubmed 8825650 "Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "CACNA1A,CACNA1B,CACNA1E,CACNB4" Pubmed 12401793 "Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RIMS2,PCLO,RAPGEF4,RAB3A" Pubmed 29466446 The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "RGS9,CNR1,GAD2,GPR88" Pubmed 16901480 A novel mode of tangential migration of cortical projection neurons. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ZEB2,OLIG1,RELN,SATB2" Pubmed 9813051 "Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "AGFG1,EPN1,ITSN1,EPN2" Pubmed 7605908 Acetylcholine esterase and peripherin mRNA level decrease in wobbler mouse. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACHE,CNTN1,NTRK3,PRPH" Pubmed 10572067 Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EGFR,ERBB2,ERBB4,PIK3R1" Pubmed 22982319 Band 4.1 proteins regulate integrin-dependent cell spreading. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "EPB41L1,EPB41L2,GFAP,EPB41L3" Pubmed 16301216 Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "SLC4A7,USH1C,ADGRV1,PCDH15" Pubmed 19109891 An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ANK2,ANK3,DMD,DCTN4" Pubmed 25998125 An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ANK3,KCNQ2,KCNQ3,SCN2A" Pubmed 20301302 "Multiple Epiphyseal Dysplasia, Autosomal Dominant" Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "COL9A1,COL9A2,COL9A3,MATN3" Pubmed 15456872 Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "PDCD6IP,EGFR,SH3KBP1,SH3GL2" Pubmed 19816407 Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn. Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "NRXN1,FYN,PTPRT,NLGN1" Pubmed 24500875 "Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo." Pubmed 4.05E-04 1.00E+00 3.42E-02 4.41E-01 4 5 "ACTN2,MYOM1,CDH2,TMOD1" Pubmed 23884446 Notch/Rbpj? signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ASCL1,HEYL,GFAP,RBPJ,HES5,NPY,SOX2" Pubmed 23420014 Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,CALB2,EDIL3,GFAP,GLUL,ITGAM,MAP2" Pubmed 22370000 SMAD4 is essential for generating subtypes of neurons during cerebellar development. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,CALB2,TBR1,GFAP,SMAD1,SMAD9,PAX6" Pubmed 23382203 Ikaros promotes early-born neuronal fates in the cerebral cortex. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "TUBB3,TBR1,GFAP,PAX6,POU3F2,S100B,SATB2" Pubmed 17360442 MafB is required for islet beta cell maturation. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "EDIL3,GCK,NEUROD1,NKX2-2,PAX6,POU3F4,ARX" Pubmed 25942625 Zeb family members and boundary cap cells underlie developmental plasticity of sensory nociceptive neurons. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ZEB2,NEUROD1,NTRK2,NTRK3,RET,SOX10,ZEB1" Pubmed 21292315 Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "HIP1R,TMEM175,MAPT,LRRK2,SNCA,SYT11,LINC02210" Pubmed 22920256 Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ASCL1,DLX1,GAD1,GBX2,NKX2-2,NPY,TAL1" Pubmed 17567809 Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ADCY2,ADCY5,ADCY6,ADCY8,WHRN,ADGRV1,MYO7A" Pubmed 29258872 Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,CALB2,GAD1,GAD2,PAX6,SLC6A9,SOX2" Pubmed 14603322 Hedgehog signalling in the mouse requires intraflagellar transport proteins. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "OLIG2,KIF3A,NKX2-2,NODAL,PAX6,PTCH1,IFT88" Pubmed 20881139 The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "TUBB3,GAP43,NCAM1,STX1B,S100B,STX1A,SYP" Pubmed 20724581 Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "NRXN3,SH2B1,NEGR1,LYPLAL1,MSRA,KCTD15,FTO" Pubmed 20064392 Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,GFRA2,NEFH,NTRK2,NTRK3,RET,UCHL1" Pubmed 11683995 Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,PLXNA4,PLXNC1,PLXNB1,PLXNB3,PROX1,RELN" Pubmed 11493566 Math5 is required for retinal ganglion cell and optic nerve formation. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,CALB2,TUBB3,NEFH,PAX6,PRKCG,STX1A" Pubmed 19641107 "Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome." Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,CALB2,GAD1,MAP2,SLCO1C1,NPY,SST" Pubmed 21983115 Laminin ?1 is essential for mouse cerebellar development. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB1,EDIL3,GFAP,LAMA2,PAX6,LAMA1,PTK2" Pubmed 29474907 Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ASCL1,CALB1,ERBB4,GAD1,SOX2,SST,AGTPBP1" Pubmed 11825874 Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "ASCL1,DLX1,GAD1,STMN2,HES5,NEUROD1,PROX1" Pubmed 25406395 RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "SPAG9,HEYL,GFRA1,RBPJ,KITLG,HEY1,ZBTB16" Pubmed 10022833 Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CSF1R,FYN,KIT,PIK3R1,TEK,VAV1,VAV2" Pubmed 17086203 Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "LHX2,BOC,CDON,NKX2-2,PAX6,ROBO3,CNTN2" Pubmed 23395374 Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "CALB2,EBF1,TBR1,L1CAM,MAPT,CNTN2,ZFPM2" Pubmed 19607792 Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Pubmed 4.11E-04 1.00E+00 3.43E-02 4.44E-01 7 16 "FGF17,CDH8,FABP7,TUBB3,TBR1,PAX6,SLC1A3" Pubmed 26332085 "Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon." Pubmed 4.17E-04 1.00E+00 3.48E-02 4.49E-01 17 72 "ARNTL,CLOCK,CRY2,CSNK1E,GFAP,PPARGC1A,HLF,HMGCR,NFE2L2,NOS1,NPY,PDE4B,PPARA,SIRT1,TJP1,TLR4,NLRP3" Pubmed 15031102 Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Pubmed 4.17E-04 1.00E+00 3.48E-02 4.49E-01 17 72 "ARHGEF25,MAGED1,AIF1L,SH3GLB1,DENND2A,GRB10,MEST,MN1,PTCH1,NKAIN1,UBR7,SMARCA4,CDK19,KANK1,SULF2,NSD2,SPATA13" Pubmed 24035498 Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. Pubmed 4.17E-04 1.00E+00 3.48E-02 4.50E-01 11 36 "ZBTB10,BACH1,CLGN,FBXL5,STRADA,HPCAL4,AHCYL1,NFE2L2,MMS19,DICER1,FBXL16" Pubmed 19170196 "Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China." Pubmed 4.28E-04 1.00E+00 3.57E-02 4.61E-01 58 383 "AXIN2,PLA2G6,ALAD,AMT,APAF1,APC,ATM,BARD1,BLM,CBR1,CBS,CCNH,CD86,SCARB1,CD81,CDC25B,CSF1R,RGS6,CTH,CX3CR1,CYBB,MATR3,DRD1,EDN1,EFNB3,EGFR,RGS17,ERBB2,ERCC2,MTHFD2,ALDH1L1,GHR,HMGCR,HSD17B1,IGF1,IGFBP1,IL6R,IL12A,LMO2,MEST,MSR1,MTR,MX1,MYO5A,NCF2,OGG1,P2RX7,ABCB1,PMS2,MASP1,RAD52,RET,RNASEL,FBXW7,RXRA,AMACR,WRN,XRCC4" Pubmed 19834535 "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." Pubmed 4.50E-04 1.00E+00 3.68E-02 4.76E-01 21 99 "SPARCL1,LDLRAD4,HAPLN1,RGS6,GPR61,GABRA4,GABRG2,GLRB,LIX1,MAP4,MATN2,MTR,FA2H,PTPRO,RPL15,ACER3,SP2,SPP1,THBS4,TPD52,FLRT2" Pubmed 17123745 Identification of genes regulated by transcription factor KLF7 in differentiating olfactory sensory neurons. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "INA,GAP43,STMN2,L1CAM,PRPH,SYP" Pubmed 1354640 A multipoint genetic linkage map of mouse chromosome 18. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ADRB2,CSF1R,DRD1,FGF1,NR3C1,MBP" Pubmed 24859200 Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "EML1,TBR1,GFAP,PAX6,S100B,PARD3" Pubmed 19318120 Fibroblast growth factor-2 increases the expression of neurogenic genes and promotes the migration and differentiation of neurons derived from transplanted neural stem/progenitor cells. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ASCL1,OLIG1,OLIG2,TBR1,HES5,NEUROD1" Pubmed 17660199 Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CRMP1,FGFR1,FGFR3,PTCH1,PTHLH,PTH1R" Pubmed 23395379 LTP requires a unique postsynaptic SNARE fusion machinery. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "DLG4,GRIA1,GRIN1,STX1B,SNAP25,STX1A" Pubmed 27641493 Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "PLPPR4,L1CAM,ENPP2,RDX,PLPPR3,SLC17A6" Pubmed 15496442 Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "BMP7,EYA1,STMN2,NEUROD1,NHLH1,SOX10" Pubmed 19700621 Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "SLIT2,B3GAT1,GBX2,ROBO1,SLIT1,SOX10" Pubmed 18926818 "TGIF, a homeodomain transcription factor, regulates retinal progenitor cell differentiation." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,ELAVL3,ELAVL4,GLUL,PAX6,SLC6A9" Pubmed 28790015 Retinoic acid controls early neurogenesis in the developing mouse cerebral cortex. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "AXIN2,TUBB3,TBR1,INSM1,PAX6,RORB" Pubmed 15733660 Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ASCL1,DLX1,TUBB3,NEUROD1,PAX6,STX1A" Pubmed 10482239 "GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ENO2,TUBB3,GFRA1,GFRA2,NEFH,RET" Pubmed 19208224 Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ASCL1,CALB1,CALB2,PPP1R1B,GAD1,HES5" Pubmed 8804307 Diversity and specialization of mammalian SWI/SNF complexes. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ARID1A,ACTL6B,SMARCA4,SMARCC2,SMARCD3,SMARCE1" Pubmed 22821687 Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "SEMA6A,GBX2,L1CAM,PAX6,RELN,CNTN2" Pubmed 27097562 Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ATP1A1,ATP1A2,ATP1A3,MITF,TJP1,ZIC2" Pubmed 25564653 ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,FABP7,TUBB3,GFAP,MAPK3,S100B" Pubmed 19244508 Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CNTNAP1,PRX,GJB1,KCNA1,PMP22,SCN8A" Pubmed 20152827 Emx2 and early hair cell development in the mouse inner ear. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "EMX2,FGFR1,GFAP,MYO7A,NEFH,PROX1" Pubmed 18590718 Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "OLIG2,HES5,NKX2-2,PAX6,PTCH1,SOX2" Pubmed 21827743 The F-box protein Fbw7 is required for cerebellar development. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,GFAP,NEFH,FBXW7,SLC17A7,SLC17A6" Pubmed 17478475 Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "DCT,ZEB2,FABP7,MITF,RET,SOX10" Pubmed 12379852 Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,DLX1,GAD1,NOS1,NPY,ARX" Pubmed 19884882 Cyclin-dependent kinases: a family portrait. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CDK13,CDK11B,CDK18,CDK14,CDK19,CDK20" Pubmed 28412462 Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "SPOP,OLIG2,GLI2,NKX2-2,PAX6,PTCH1" Pubmed 21632926 Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "RBPJ,MYO6,PROX1,SOX2,HEY1,HEY2" Pubmed 15590934 Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "NOG,DLX1,ETV1,TUBB3,GFAP,RELN" Pubmed 1572638 Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ATP1A1,ATP1A2,ATP1A3,MBP,NCAM1,SST" Pubmed 27648578 Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "DCC,TBR1,GFAP,L1CAM,ROBO1,SYP" Pubmed 18223201 Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "OLIG2,TUBB3,NEUROD1,NKX2-2,PAX6,CUX2" Pubmed 12189208 Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "NCOA1,MED24,ABCC9,PPARGC1A,PPARA,MED1" Pubmed 16234809 Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "LHX2,SLC32A1,GAD1,GAD2,STMN2,SLC17A6" Pubmed 24723342 The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CDH8,ETV1,TBR1,MEF2C,NOS1,FEZF2" Pubmed 21991391 Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "NRP2,LHX2,TBR1,PROX1,RELN,DICER1" Pubmed 16787938 "Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosome related functions." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "MTMR9,MTMR3,MTMR2,MTMR7,MTMR10,SBF1" Pubmed 17331196 "Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB2,DLG3,SCIN,MYO6,MYO7A,RTKN" Pubmed 8424456 "Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "MYH6,MYH7,MYH14,TPM1,TPM2,TPM3" Pubmed 23093780 PPAR?/? affects pancreatic ? cell mass and insulin secretion in mice. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "NEUROD1,NKX2-2,PAX6,POU3F4,PPARA,SST" Pubmed 15834408 The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CDH2,CTNND1,TUBB3,KIF5A,KIF5C,KIF1B" Pubmed 19759535 Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CDH8,EFNA2,EFNA3,EPHA5,RELN,SOX5" Pubmed 10729342 Emx2 is required for growth of the hippocampus but not for hippocampal field specification. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "EMX2,EPHB1,TUBB3,GRIK3,GRIK4,KITLG" Pubmed 24626607 Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB2,ETV1,NPY,RORB,SST,CUX2" Pubmed 15457338 A gene-driven ENU-based approach to generating an allelic series in any gene. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "MRO,FOXF2,NEGR1,KCNJ11,FTO,ATMIN" Pubmed 22595669 IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "OLIG2,GLI2,NKX2-2,PAX6,PTCH1,IFT88" Pubmed 11830575 Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,SLIT2,PAX6,ROBO1,ROBO2,SLIT1" Pubmed 12880961 Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ARFGAP2,NCOA7,NXPH1,OXR1,ATAT1,POGZ" Pubmed 25574476 "Mutations in PTRH2 cause novel infantile-onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,CALB2,GFAP,MAP2,MAPK3,PTK2" Pubmed 21673655 FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "PAX6,UNC5B,UNC5D,SATB2,FLRT2,FLRT1" Pubmed 22998873 gdnf activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "DCC,GFRA1,NCAM1,NRCAM,RET,SEMA3B" Pubmed 21072209 Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "BMP7,SPAG9,CLGN,CCDC80,MAPK8,VAV2" Pubmed 27399837 "Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility." Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ESYT2,OSBPL8,EDIL3,SYT3,TMEM110-MUSTN1,SYT1" Pubmed 21270798 Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "SEMA6A,NRP2,PLXNA4,PLXNC1,PLXNB1,PLXNB3" Pubmed 27707970 A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "EDIL3,ETV1,MAPT,NEFH,RET,S100B" Pubmed 20018852 Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "OGT,KAT8,MSL3,MSL1,KANSL1,KANSL3" Pubmed 16766712 Cellular patterns of transcription factor expression in developing cortical interneurons. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB2,DLX1,GAD1,ARX,SST,CUX2" Pubmed 11688560 Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "BMP7,CBLN1,EYA1,SALL3,RET,SALL1" Pubmed 21761479 PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "OLIG2,NKX2-2,PAX6,FUZ,VANGL2,IFT88" Pubmed 20034568 Runx3 is required for the specification of TrkC-expressing mechanoreceptive trigeminal ganglion neurons. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CALB1,CALB2,NTRK2,NTRK3,SST,TAC1" Pubmed 18579745 Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "CNTNAP1,DRP2,ITGAM,KCNA1,RDX,NFASC" Pubmed 20185807 Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "MADD,DGKB,GCK,IGF1,PROX1,TCF7L2" Pubmed 20038947 Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Pubmed 4.52E-04 1.00E+00 3.68E-02 4.76E-01 6 12 "ATP6V0A1,LY86,LINC-PINT,GRM7,MKLN1,SP4" Pubmed 18654987 Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. Pubmed 4.59E-04 1.00E+00 3.74E-02 4.83E-01 22 106 "NCKAP5,LTBP4,EIF4G3,GAPVD1,CEP170,PLEKHA1,CEP78,TRMO,NFU1,CRCP,MSL1,PIK3AP1,PPM1B,RBBP6,SH3BGR,ITSN1,GKAP1,SRPK2,POGZ,DNMBP,NR2C2,VAV2" Pubmed 20682791 A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. Pubmed 4.67E-04 1.00E+00 3.80E-02 4.91E-01 15 60 "ANK2,DST,PCYT1B,DCTN1,DYNC1I1,DCTN2,KDM2B,GOLGB1,GAREM2,MYH7,HNRNPM,PSMA6,KIF1B,SYNE1,TUBA1A" Pubmed 21441570 Genome-wide meta-analysis for severe diabetic retinopathy. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "CREB5,IGSF21,IRF8,KCNK1,VEPH1,MYT1L,TAB2,MPRIP,TCF4,TCF7L2" Pubmed 8681137 Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "ANK1,PDE4DIP,FLNC,SYNPO,MYLK2,TMIE,TNPO2,SLN,OBSL1,TNNT1" Pubmed 21138975 Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "HES5,MITF,NEUROD1,PAX6,PTCH1,RLBP1,STX1B,SOX2,STX1A,DICER1" Pubmed 22076636 Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "CHRD,BMP7,NOG,SLIT2,SEMA3D,FGFR1,FGFR3,PTCH1,UNC5B,SEMA3B" Pubmed 27100196 Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "CDH8,CRYM,EMX2,GAP43,GBX2,KITLG,MDGA1,PAX6,RBBP8,RORB" Pubmed 23426374 Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "BMP7,VAX2,CRYBB1,TUBB3,SMAD1,SMAD9,MITF,PAX6,PROX1,SOX2" Pubmed 16000382 Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Pubmed 4.68E-04 1.00E+00 3.80E-02 4.91E-01 10 31 "NEURL1,HEYL,ELAVL3,ELAVL4,DLL3,RBPJ,HES5,NEUROD1,HEY1,HEY2" Pubmed 19538736 Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. Pubmed 4.79E-04 1.00E+00 3.89E-02 5.03E-01 13 48 "NR0B1,AMH,CLGN,TENM4,PLXNC1,GDF9,PCDH11X,KCND2,KITLG,CLSTN2,LRRC4,TCF4,ZBTB16" Pubmed 20826531 The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CHRD,ATM,GBX2,MEIS2,NODAL,PKNOX2,SOX1,LEFTY2" Pubmed 21690297 Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "MAD2L2,STAG2,HSF2,PPP3CA,PPP3CB,RAD51D,TEX15,UBC" Pubmed 18721803 A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CCK,GAD1,NEUROD1,NEUROD2,NPY,PDYN,PENK,TAC1" Pubmed 17032746 The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "SYT13,CHGA,CDHR1,MYT1,NNAT,IRX1,SST,RHBDL3" Pubmed 16987518 Disruption of parental-specific expression of imprinted genes in uniparental fetuses. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "SGCE,GRB10,MEST,NNAT,MAGEL2,SNRPN,PEG10,MKRN3" Pubmed 27600842 The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "EBF1,FOXG1,TBR1,GBX2,MEF2C,SOX5,SOX11,SATB2" Pubmed 22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "ARHGEF2,NRXN3,KIAA0513,PCSK5,ST3GAL3,ZNF142,ANKS1B,CPNE4" Pubmed 20159594 Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "OLIG2,GLI2,NKX2-2,PAX6,PTCH1,CDK20,TUBA1A,IFT88" Pubmed 24946904 Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CALB1,EN2,GFAP,MYCN,NEUROD1,PAX6,PTCH1,RFX3" Pubmed 27568557 Identification of Modifier Genes in a Mouse Model of Gaucher Disease. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "DPP10,RGS6,CTNND2,GCK,TOX3,GRIK2,FAT4,KCNIP1" Pubmed 20089898 Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "EMX2,ETV1,FOXG1,LIX1,PAX6,RELN,FEZF2,CUX2" Pubmed 17065231 BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "BMPR1B,FGFR1,SMAD1,SMAD9,MAPK3,PTCH1,PTH1R,SPP1" Pubmed 22258620 Pten coordinates retinal neurogenesis by regulating Notch signalling. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CALB1,MAML1,TUBB3,GLUL,RBPJ,PAX6,PROX1,SOX2" Pubmed 25512300 Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "ASCL1,DLX1,GAD1,NKX2-2,ARX,SOX2,TAL1,SLC17A6" Pubmed 30021842 SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CDH2,NOG,SEMA3D,ENPP2,MYH14,SOX6,ABLIM3,SOX5" Pubmed 22748019 The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "DCC,EN2,GFRA1,MEIS2,PBX1,RET,SNCA,MEIS3" Pubmed 21087508 MATH5 controls the acquisition of multiple retinal cell fates. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CALB1,CALB2,GAD2,GNAO1,NEUROD1,PAX6,PROX1,RXRG" Pubmed 25190801 Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "ATP1A3,CACNA1D,DCC,ABCC9,EDN1,LYVE1,ITGA7,KCND2" Pubmed 25926459 Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "AXIN2,TUBB3,GFAP,L1CAM,PAX6,MAPK3,PROX1,RELN" Pubmed 24631216 BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "AXIN2,BMP7,CDH2,NOG,FOXG1,PRKCZ,SOX2,ZEB1" Pubmed 25995483 Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "CALB1,CALB2,GAD1,GAD2,PAX6,KCNIP3,S100B,SLC6A9" Pubmed 21571225 ?-Catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "FGF17,BMPR1B,FGFR1,FGFR3,FOXG1,FOXO3,TJP1,PARD3" Pubmed 23535733 Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Pubmed 4.89E-04 1.00E+00 3.94E-02 5.09E-01 8 21 "MRTFA,N4BP2L1,EBF1,TOX3,MDM4,FTO,PTHLH,ZNF365" Pubmed 20637190 O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Pubmed 4.95E-04 1.00E+00 3.98E-02 5.15E-01 17 73 "UNC5A,ADGRB1,ADGRB2,ADGRB3,THSD7A,ADAMTS13,ADAMTS8,ADAMTS6,NODAL,SEMA5B,SOX2,SSPO,ADAMTS17,LEFTY2,ADAMTS9,ADAMTSL3,ADAMTS10" Pubmed 23398456 The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Pubmed 4.96E-04 1.00E+00 4.00E-02 5.17E-01 51 328 "RBM10,AP2A2,CALM1,INA,AIFM1,CFL2,MYL6B,CLTA,CLTB,CLTC,CNN3,CSF1R,MATR3,DBN1,CEP170,SEC16A,PAN3,TUBA1B,PRMT5,SPECC1,ZNF234,HBA1,HSP90AA1,DOCK7,STMN1,MT1M,MYO5A,MYO6,HNRNPM,TMOD2,PKM,PLEC,PPM1B,MYH14,RPL15,RPL38,SFPQ,MYO18A,EFHD1,ERC1,SPTAN1,CLASP2,MPRIP,TJP1,TMOD1,TPM1,TPM3,TPM4,TUBA1A,HNRNPA3,ACTR3B" Pubmed 28720576 Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway. Pubmed 4.99E-04 1.00E+00 4.01E-02 5.18E-01 9 26 "MPDZ,ARMC8,CSNK1E,DCTN1,AMOTL2,RAPGEF6,CIT,WWC1,AMOT" Pubmed 20510229 Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Pubmed 4.99E-04 1.00E+00 4.01E-02 5.18E-01 9 26 "SYT13,ASCL1,DLX1,ELAVL4,GAP43,WIF1,KLHL4,WNT7A,KCNAB1" Pubmed 24741061 Robo1 modulates proliferation and neurogenesis in the developing neocortex. Pubmed 4.99E-04 1.00E+00 4.01E-02 5.18E-01 9 26 "SLIT2,TUBB3,PAX6,ROBO1,ROBO2,SLIT1,ZNF423,ROBO3,HEY1" Pubmed 24706806 Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo. Pubmed 4.99E-04 1.00E+00 4.01E-02 5.18E-01 9 26 "AXIN2,CDH2,EDIL3,NKX2-2,PAX6,PTCH1,TP53BP1,VANGL2,IFT88" Pubmed 22182523 Redundant functions of Rac GTPases in inner ear morphogenesis. Pubmed 4.99E-04 1.00E+00 4.01E-02 5.18E-01 9 26 "EYA1,TUBB3,FOXG1,GBX2,MYO6,MYO7A,NEUROD1,SOX2,TJP1" Pubmed 19723774 Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Pubmed 5.32E-04 1.00E+00 4.27E-02 5.52E-01 16 67 "INTS2,KRIT1,DBI,ARFGAP2,KCNB1,STMN1,NASP,PTN,FBXO11,SPP1,EXOC7,ITGB3BP,HEY1,HEY2,ZFAND5,NELFE" Pubmed 16094384 Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. Pubmed 5.34E-04 1.00E+00 4.29E-02 5.54E-01 18 80 "C1QTNF4,PKP4,CAPRIN2,ADAM23,ARHGEF6,DBN1,DMD,SEC24B,STMN1,MBD1,DBNL,REV3L,PBRM1,ERBIN,TP53BP1,WBP2,TRIO,PLD4" Pubmed 16196087 Large-scale analysis of the human ubiquitin-related proteome. Pubmed 5.41E-04 1.00E+00 4.34E-02 5.61E-01 49 313 "FGD2,APC,DCAF5,BTRC,CBS,USP2,FBXO7,RBM39,TCAF1,MATR3,G3BP2,TOM1,DNAJB6,FRY,RBM12,COPS4,FHL1,SYNCRIP,NOP56,DCTN2,TNRC6A,GLUL,HNRNPK,MTR,MYO6,NACA,HNRNPM,NAP1L1,NASP,PCMT1,PFKFB2,PSAT1,PSMA6,LAMA1,OCIAD1,PNMA8A,RPS20,SFPQ,KIF21B,MYCBP2,SPART,NCDN,PJA1,TRO,UBC,AMOT,TBC1D15,HNRNPA3,LAS1L" Pubmed 1302014 Evolution of the mammalian G protein alpha subunit multigene family. Pubmed 5.42E-04 1.00E+00 4.35E-02 5.62E-01 11 37 "CCK,CSF1R,EN2,GNAL,GNAO1,GNAS,HP,MBP,PAH,TF,THRA" Pubmed 28576773 "Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets." Pubmed 5.42E-04 1.00E+00 4.35E-02 5.62E-01 11 37 "CHGA,KCNJ11,NEUROD1,NKX2-2,PAX6,PCSK1,ARX,SST,ABCC8,SYP,RICTOR" Pubmed 26534985 NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo. Pubmed 5.42E-04 1.00E+00 4.35E-02 5.62E-01 11 37 "AXIN2,CHRD,EDIL3,TUBB3,GBX2,RBPJ,HES5,NODAL,SOX1,SOX2,LEFTY2" Pubmed 25900982 BioID-based Identification of Skp Cullin F-box (SCF)?-TrCP1/2 E3 Ligase Substrates. Pubmed 5.51E-04 1.00E+00 4.42E-02 5.71E-01 38 226 "RTL9,OGT,APC,BTRC,CDC25B,CLTC,MAGED1,ACBD5,NOS1AP,SMG7,MRPL37,SYNCRIP,FLNC,PDLIM5,WASHC2A,TNRC6A,USP54,MTR,NFE2L2,NRDC,C11orf49,LRRC49,USP47,MRPS18A,FNIP1,SIRT2,ELMO2,FAM219A,ERBIN,NSFL1C,FBXW11,TJP1,PLEKHH2,ZIC2,TRIM9,GOPC,MRPL47,HNRNPA3" Pubmed 22442722 Functional consequences of necdin nucleocytoplasmic localization. Pubmed 5.64E-04 1.00E+00 4.52E-02 5.84E-01 15 61 "PPFIA3,HAP1,CDH2,COPB2,RCBTB2,IFFO1,DCTN1,C8orf37,DNER,NUCB1,PCDH18,RUFY2,KIF21B,POGZ,TUBA1A" Pubmed 23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Pubmed 5.82E-04 1.00E+00 4.66E-02 6.02E-01 25 129 "LCORL,JAZF1,NRXN3,LY86,SH2B1,EPB41L1,EFEMP1,DOT1L,HNF4G,NEGR1,LYPLAL1,HS6ST3,PCSK5,FTO,PPM1B,SCMH1,COLGALT2,ADAMTS17,FBXW11,HHIP,DCBLD1,ZBTB38,AMZ1,CADM2,ADAMTSL3" Pubmed 24357327 Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Pubmed 5.82E-04 1.00E+00 4.66E-02 6.03E-01 12 43 "CDH2,FCGR1A,L1CAM,NCAM1,NTRK2,NTRK3,ZDHHC8,PRODH,ROBO1,ROBO2,ROBO3,HIRA" Pubmed 17687036 Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. Pubmed 5.82E-04 1.00E+00 4.66E-02 6.03E-01 12 43 "AXIN2,ASCL1,FGF17,ELAVL3,ELAVL4,FGFR1,GBX2,HES5,NEFH,PAX6,SOX2,SOX3" Pubmed 21150899 Subtypes of medulloblastoma have distinct developmental origins. Pubmed 5.87E-04 1.00E+00 4.70E-02 6.07E-01 14 55 "SEMA6A,COL4A5,COL9A3,CSNK1E,GAD1,GALR1,WIF1,NHLH1,PAX6,LRRN3,PTCH1,LGI2,SATB2,ZIC1" Pubmed 7774911 Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse. Pubmed 5.95E-04 1.00E+00 4.76E-02 6.15E-01 13 49 "ALAD,C5,CNTFR,GCNT2,GRIN1,GSN,RXRA,SPTAN1,TMOD1,VAV2,VLDLR,ZFP37,NUP214" Pubmed 18023262 Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Pubmed 5.95E-04 1.00E+00 4.76E-02 6.15E-01 13 49 "KDM5D,RUNX1T1,SNCAIP,LPAR6,FOXG1,FOXF2,DACH2,NR3C1,ING3,ZIK1,SMARCE1,ZFPM2,ZFP37" Pubmed 24146773 The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. Pubmed 6.04E-04 1.00E+00 4.83E-02 6.24E-01 32 181 "PHF12,BACH1,RUNX1T1,LHX2,ZNF385A,NCOR2,EBF1,HEYL,ELAVL2,EMX2,EN2,SALL3,GBX2,GLI2,HES5,LMO2,MEIS2,MYCN,NFIA,PAX6,PRRX1,ING3,POU3F4,IRX1,PROX1,PKNOX2,SMARCA4,SMARCE1,KANK1,TBX15,TCF7L2,HEY1" Pubmed 25715395 Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "HEYL,KLF12,RBPJ,HES5,PKD1,PRKCZ,SPP1,SST,HEY1,HEY2" Pubmed 24954895 "Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia." Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "AS3MT,KLHL32,GOLGA7B,ATP2B1,DAPK1,KCNMA1,POC1B,FIGN,RXRA,PRDM8" Pubmed 22424883 Genome-wide association study of lung function decline in adults with and without asthma. Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "ANK1,PLXNA4,CTNND2,PCDH9,CNTLN,KANK1,SYNE2,CSMD1,FLRT2,PCDH15" Pubmed 23364326 The transcription factor Otx2 regulates choroid plexus development and function. Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "AXIN2,PROM1,CALB2,FGF12,TBR1,WIF1,HES5,PAX6,PENK,RELN" Pubmed 22087225 Biochemical and computational analysis of LNX1 interacting proteins. Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "PLEKHG5,SHTN1,RASL11B,DAPK1,WAC,LNX1,KCNA4,CAMK2N2,SNCB,INKA2" Pubmed 26951610 Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. Pubmed 6.22E-04 1.00E+00 4.96E-02 6.41E-01 10 32 "NDRG2,DMPK,STMN1,MAPT,NEFH,KCNIP1,ATXN2,NTNG1,TROVE2,TTC3" Interaction int:TNIK TNIK interactions 1.49E-30 2.17E-26 2.17E-26 2.21E-25 136 282 "AP2A1,AP2A2,LRRC7,BIN1,ANK2,ANK3,APC,CASK,ZSCAN18,CCAR2,DOCK11,DST,WASF1,CACNA1A,CACNA1E,CACNA2D1,CACNB4,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SHISA7,INA,DGKI,ARHGEF2,CDH2,CDH10,DCLK1,DLGAP1,TAOK2,CLU,NGEF,MAP4K4,HOMER3,NCOR2,SEC24C,SIPA1L1,PDE4DIP,ERC2,CTNND1,CTNND2,ARHGAP32,MATR3,ZEB2,TIAM2,CEP170,MAGI2,SNAP91,SRGAP3,DLG2,DLG3,DLG4,DNM1,SHANK1,DPYSL2,ABI1,EGFR,ABI2,MTSS1L,BAIAP2,CAP2,AGAP2,NOP56,NBEA,NEURL4,NCKAP1,DISC1,GLUL,PRRC2B,RAPGEF4,GRIA1,GRIA2,GRIK2,GRIN1,GRM5,CIT,GSN,DOCK7,KCNMA1,KIF2A,KIF5A,KIF5C,GIT1,MYO5A,RCOR2,NEFM,NOS1,HCN1,PCDH8,CAMKV,STRN3,SH3KBP1,PPP3CB,PRKACB,PRKAR1B,PRKCB,PRKCG,IQSEC3,KIF7,TRIM46,SH3GL2,PPM1E,CNKSR2,SHANK2,SMARCC2,SMARCE1,RIMS1,TNIK,MYCBP2,SPTAN1,IQSEC2,TAB2,SEPT3,GSE1,ZC3H4,SYNE2,ARC,WWC1,AGTPBP1,TRIM2,CLASP1,SYNE1,TJP1,RIMBP2,CABIN1,TNR,TP53BP1,TRIO,TSC1,TUBB2A,HIRA,XPO1,ZIC2,PAK5,FXR1" Interaction int:DLG4 DLG4 interactions 3.77E-28 5.49E-24 2.51E-24 2.55E-23 129 272 "ABR,ASIC2,ACTN2,NLGN4X,LRRC7,PCDH10,BEGAIN,LRFN1,ANK3,CNTNAP1,KCNAB2,ALS2,SEMA4G,CASK,DYNLL1,ATP1A1,ATP2B2,ADGRB1,ADGRB3,SYNJ1,KALRN,CAMK2A,CAMK2B,CAMK2D,INA,LGI1,DLGAP2,DLGAP1,ASIC3,RAB3C,DLGAP3,NRXN1,CLU,CLTC,CNTN1,AKAP5,GDA,SIPA1L1,ARHGAP32,DBN1,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DPYSL2,ABI1,ERBB2,ERBB4,CACNG2,PTK2B,BAIAP2,AGAP2,NBEA,SORBS1,ADGRA1,FYN,NCKAP1,IQGAP2,GLUL,GNAO1,GPM6A,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM3,CIT,KIF3A,PTPN5,GUCY1A2,ZDHHC15,HTR2A,TJAP1,TUBB2B,KCNA1,KCNA2,KCNA4,KCND2,KCNJ4,KCNJ10,KCNJ16,KIF2A,KIF5A,MPP2,GIT1,ADAM22,NCAM1,NEFH,NOS1,NRCAM,NTRK2,PDE2A,NLGN3,PIK3C2A,PLP1,SH3KBP1,PPP3CA,PPP3CB,PRKACB,PRKCB,PRKCG,PTK2,PTPRG,MAPK12,CNKSR2,NLGN1,SLC1A2,FAM81A,SHANK2,TNIK,KIF1B,IQSEC2,EPB41L3,ERBIN,SYNE2,ARC,SYT1,SYNE1,TSC1,ANKS1B,LRP8,KCNAB1,NETO1" Interaction int:DLGAP1 DLGAP1 interactions 5.18E-28 7.52E-24 2.51E-24 2.55E-23 94 167 "TMEM132B,CASKIN1,LRRC7,BEGAIN,CNTNAP1,APC,CASK,DYNLL1,ADGRB2,ADGRB3,MPDZ,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SEPT7,LGI1,DLGAP2,DLGAP1,DLGAP3,NRXN1,MAP4K4,HOMER3,CTNND1,CTNND2,ARHGAP32,DBN1,DNAJC6,SNAP91,DLG2,DLG3,DLG4,DNM1,SHANK1,DPYSL2,EPB41L1,RACK1,BAIAP2,AGAP2,NBEA,SORBS1,NCKAP1,IQGAP2,GLUL,RAPGEF4,GRIA1,GRIA2,GRIN1,GRIN2C,GRIN2D,CIT,GSN,SYNPO,LRRTM1,KCNA1,KCNA2,KCNA4,KCNJ4,KCNJ10,KIF2A,KIF5A,KIF5C,GIT1,ADAM22,MYO5A,NEFH,PDE4B,SH3KBP1,PPP3CA,PPP3CB,PRKCB,PRKCG,MAPK3,PTK2,IQSEC3,ITSN1,CNKSR2,SHANK2,TNIK,SPTAN1,IQSEC2,DDN,EPB41L3,ERBIN,NCDN,MPRIP,SEPT3,ARC,SYNE1,TRIO,KCNAB1,FXR1" Interaction int:AGAP2 AGAP2 interactions 2.84E-27 4.14E-23 1.03E-23 1.05E-22 102 193 "RALGAPA1,ACTN1,AP2A1,AP2A2,AP1B1,KCTD16,LRRC7,ANK3,PPFIA2,PPFIA1,SYNJ1,WASF1,CACNA1E,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,INA,SEPT7,CDC42,DCLK1,DLGAP2,DLGAP1,NUMBL,DLGAP3,CLTC,CRMP1,PDE4DIP,APPL1,RIMS2,DBN1,SRGAP3,AK5,DLG2,DLG3,DLG4,DNM1,DYNC1I1,SHANK1,DPYSL2,EPB41L1,EPB41L2,GPHN,PTK2B,AGAP2,NBEA,SORBS1,CAMKK2,NCKAP1,IQGAP2,GLUL,GNAO1,GNAS,PCLO,RAPGEF4,GRIA1,GRIA2,GRIN1,GRM1,GRM2,GRM3,GRM5,GSN,MAP6,GIT1,MYO5A,NCAM2,NF1,NRCAM,NLGN3,PIK3R1,PPP3CA,PPP3CB,PRKACB,PRKCB,PRKCG,PKN2,MAPK3,MAPK10,PTK2,IQSEC3,PPP1R9A,PPM1E,CNKSR2,NLGN1,SHANK2,RIMS1,TNIK,SPTAN1,IQSEC2,EPB41L3,NCDN,MPRIP,STXBP1,SYNE1,SIK3,TNR,TP53BP2,PRMT8,TRIO,ANKS1B" Interaction int:DGUOK DGUOK interactions 1.07E-22 1.56E-18 3.12E-19 3.17E-18 51 71 "SLC12A5,AMPH,BIN1,ANK2,APP,ATP2B2,ATP2B3,CALB2,CAMK2A,CAMK2B,DCLK1,CNTN1,CRMP1,ERC2,SNAP91,NTM,DNM1,DPYSL2,DNM1L,EDIL3,EEF1A2,ELAVL4,EPB41L1,NCALD,HPCAL4,DPYSL4,GNAO1,GPM6B,GRIA2,HPCA,L1CAM,LIG4,MAP2,MAPT,NCAM1,GNG2,CAMKV,RAB3A,STX1B,NAPB,SNAP25,SNCB,SNCA,STX1A,STXBP1,SYN1,SYN2,SYP,SYT1,VSNL1,DPYSL5" Interaction int:SHANK3 SHANK3 interactions 1.97E-22 2.86E-18 4.77E-19 4.85E-18 86 166 "CASKIN1,LRRC7,ANK3,CNTNAP1,SPTBN4,HCN2,ARHGEF7,WASF1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,INA,SEPT7,DCLK1,DLGAP2,DLGAP1,TAOK2,DLGAP3,MAP4K4,HOMER3,CNTN1,CDC42BPB,NCAN,PDE4DIP,ERC2,PPP6R2,SIRPA,DBN1,DCTN1,SNAP91,DLG2,DLG4,DNM1,SHANK1,ABI1,ABI2,EPB41L1,BAIAP2,AGAP2,NCKAP1,GLUL,RAPGEF4,TPPP,GRIN1,GRM2,GRM3,GRM5,CIT,SYNPO,KIF5C,MPP2,MYO5A,NF1,NRCAM,HCN1,PAX6,PPP3CA,PPP3CB,PRKCB,PRKCG,MAPK3,RET,KIF7,RPS6KA2,KIF21A,PPP1R9A,CNKSR2,SHANK2,TNIK,HECW1,SPTAN1,IQSEC2,NFASC,EPB41L3,NCDN,SEPT3,PLCB1,ANKRD28,SYNE1,TNR,TSC1,ANKS1B,FXR1,SPATA13" Interaction int:SYNGAP1 SYNGAP1 interactions 4.22E-21 6.14E-17 8.77E-18 8.91E-17 76 142 "LRRC7,BEGAIN,PITPNM2,AMPH,CNTNAP1,KCNAB2,DGKZ,ADGRB2,MPDZ,SYNJ1,CACNB2,KALRN,CAMK2A,CAMK2B,DLGAP2,DLGAP1,RAB3C,DLGAP3,CNRIP1,GDA,NCAN,ARHGAP32,DBN1,KBTBD11,DLG2,DLG3,DLG4,DNM1,SHANK1,DPYSL2,DNM1L,EPB41L2,CACNG2,PTK2B,BAIAP2,AGAP2,NBEA,SORBS1,IQGAP2,GLUL,GNAO1,GNAS,LNX1,GRIA1,GRIA2,GRIN1,GRIN2D,GRM5,SHISA6,ITPKA,KCNA4,KCNJ10,GIT1,ADAM22,MYO5A,NCAM1,NTRK3,OPA1,PLCL1,PRKCG,MAPK3,RAB3A,CNKSR2,SLC1A3,FAM81A,SHANK2,TNIK,MYCBP2,IQSEC2,DDN,SYN1,ARC,DMXL2,WDR7,TSC1,ANKS1B" Interaction int:DNAAF2 DNAAF2 interactions 5.94E-19 8.63E-15 1.08E-15 1.10E-14 52 83 "AMPH,ANK2,ALS2,APP,ATP2B2,CACNA2D1,CALB2,CALM1,CAMK2A,CAMK2B,DCLK1,CNTN1,CRMP1,PLXNA4,SNAP91,DNM1,DPP6,DPYSL2,DNM1L,EPB41L1,NCALD,HPCAL4,DPYSL4,FAM49B,PHYHIPL,GNAO1,GPM6A,GPM6B,GRIA2,HPCA,L1CAM,LSAMP,MAPT,NCAM1,GNG2,CAMKV,RAB3A,STX1B,NAPB,SNAP25,SNCB,SNCA,STX1A,SEPT3,STXBP1,SYN1,SYN2,SYP,SYT1,VSNL1,NDRG4,DPYSL5" Interaction int:HNRNPL HNRNPL interactions 3.17E-16 4.61E-12 5.12E-13 5.21E-12 435 1671 "RALGAPA1,ABAT,KCNH8,ABR,ARID1A,PLEKHH1,SNX30,ESYT2,LRFN2,KIDINS220,MTA3,ZNF608,INTS2,GPR158,TBC1D14,PLA2G6,LRRC7,SEMA6A,ALCAM,TRMT9B,PITPNM2,OGT,CDC42BPA,ANK3,PPFIA2,ANXA7,APBB2,TNRC6C,APP,SHTN1,SHROOM2,CDC14B,SFMBT2,PPP4R4,PDXK,CASK,SPTBN4,ARRB1,ARRB2,CDK13,ASPH,NUMB,EIF4G3,ATP2B1,SLC2A11,KIF1A,BARD1,BMPR1B,SYNJ2,FUBP1,BAIAP3,DDR1,CACNB2,PTBP2,CAMK2B,CAST,CBFA2T2,SCARB1,LRBA,ZMYM4,EVI5L,MAGI1,NUMBL,CACNA2D2,ADGRG1,SRSF11,FOXN3,CASC2,KMT2C,EPS15L1,RPL32P3,RAB28,NGEF,FAM19A5,HECTD1,FAM149A,COL4A5,BTF3L4,MYRIP,CHD1L,ZNF385A,CDC42BPB,C2CD2,RBM39,SH2B1,ANKRD44,NCOR2,ABCG1,MICAL2,RASGEF1C,SDC3,PHF14,GREB1,ARHGEF4,CTNND1,DOCK4,DCAF8,HDAC4,TM9SF4,TBC1D5,MATR3,CTIF,PLEKHM1,HP1BP3,CEP170,ZC3H11A,SMG7,SGSM2,USP3,RPS6KL1,TRAPPC9,SLC12A6,DPP6,DPYSL2,PDCD6IP,DTNA,DTNB,TOM1,SNX29,EEF1A2,SGK2,HIPK3,FAM13A,SUGP2,EGFR,MBNL2,ELAVL2,TNK2,BSCL2,PAN3,HSD17B14,VPS13B,EPB41,EPB41L1,ERBB2,ETV1,RTN3,ANKMY1,KATNAL1,ADGRV1,NSRP1,ZNF461,SH3YL1,ZNF589,FECH,KIAA1109,FGF13,FGFR3,BAIAP2,PRKAG2,POLK,SCARA3,UBE2E3,CAP2,SYNCRIP,AGAP3,FOXO3,EVL,SEMA4D,FOLH1,POMT1,ATP2C1,NRG3,MPP6,ABLIM2,ZNF512,ZMAT1,STAG2,ZNF44,NEK6,TMEM8B,SEPT9,STARD10,WASF3,SESN1,AHDC1,MALT1,SPIN1,GLI2,GLYR1,TOX3,ZNF638,OS9,LUZP2,DCLK2,RAB40B,GNAS,GNG4,GPT2,GOLGB1,PRUNE2,ATF7,FUT10,GRB10,PARD3B,GRIK1,GRIK2,RNF165,BVES,GUCY1A1,HPS5,MAN1B1,FRMD3,SYNPO,HNRNPK,IGF1,KNDC1,TJAP1,IL6R,ZNF385B,ITPKB,JAK2,KCND3,KCNJ3,KLHL23,KCNMA1,KCNN2,KIF5C,LSS,PACRG,MAP2,MAP4,MAPT,MARK3,MBNL1,MBP,MDM4,MKLN1,AFF1,MMP16,MRPL42,STK32C,MSRA,MYO5A,MYO6,MYO9A,MYT1,HNRNPM,NCAM2,NFIA,NFIX,NOVA2,KSR2,NUCB2,OGDH,OPRL1,GPR137C,ZNF827,PAK3,PBX1,PDE3B,PDE4D,PFKFB4,CDK14,NLGN3,PLEC,PSAT1,SPATA6,EPB41L4B,POLG,PPARA,TATDN3,PPP2R2C,PPP3CA,VSTM2L,PRKACB,PRKAR1B,PRKCZ,NDUFS7,BCAS3,VPS13C,SLC22A23,WDR25,PTK2,PTPN13,PTPRB,PTPRE,PTPRG,PTPRN2,FAM120C,C1orf109,RIPOR1,MARCH1,RAD52,ZNF793,HKR1,KHDRBS2,ZDHHC14,TRIM68,SLC25A36,RIC8B,ZNF532,SETD5,MYH14,KIAA0895L,SGSM1,RPS6KA2,ATAT1,KCNIP3,YJEFN3,KCNIP2,RXRA,ZNF331,ATXN1,ATXN2,ATXN7,SCP2,FNIP1,TNFRSF19,CASC3,GALNT10,SFPQ,RASA3,PUF60,SCAF8,NLGN4Y,SH3BGR,SH3BP2,PPP1R9A,FRMPD1,MAGI3,CHD9,SLITRK3,ST3GAL3,WDR37,NBPF1,KANSL3,PKNOX2,SHANK2,EFHD1,NAXD,MAST1,RCOR3,TTC17,IFT122,IGSF9B,LIMCH1,RIMS1,MBD5,TMCC1,KDM4B,DOP1A,PDZD2,BDP1,FNBP1,NMNAT2,MYCBP2,SPTB,KIF1B,CDK19,TSPYL2,NFASC,LHPP,SRPK2,CLASP2,ZC4H2,LARP4,SSPO,ERBIN,ST5,NCDN,INKA2,MAPK8IP3,PHLDB1,FAM168A,ABCC8,ARHGEF9,COBL,ASTN2,ATP11A,ANKRD12,PJA1,CAMTA1,MCF2L,FBXW11,TBL1X,SMG6,MGRN1,ATMIN,EHBP1,TCF7L2,TPCN2,PCDHGB1,OBSL1,FRYL,AHCYL2,THRA,NACC2,TJP1,TMPO,ANKRD24,CSMD1,PARD3,KAT6B,RBFOX2,TRIO,TRPM2,TRPS1,TMPRSS5,TTTY15,HSPBP1,TTC3,TMEFF2,UBE2H,SLC35A4,VAV2,BEST1,LMF1,NSD2,PORCN,SF1,ZNF708,ZBTB16,ZNF189,DPYSL5,SPIRE1,SMARCAD1,MEIS3,INTS3,SLC30A4,MAP3K12,LRP8,CSDE1,VPS35L,SEMA3B,CAB39L,WNK2,ST7,KAT6A,HNRNPA3,TMEM63C,CERS6,JMJD1C,ZNF248,NETO1" Interaction int:NUFIP1 NUFIP1 interactions 4.96E-16 7.21E-12 7.21E-13 7.33E-12 60 116 "ADD2,SLC12A5,AMPH,BIN1,ANK2,ATP2B2,ATP6V0A1,CALB2,CAMK2A,CAMK2B,CCNT1,DCLK1,CNTN1,CRMP1,SNAP91,NTM,DNM1,DPYSL2,DNM1L,EDIL3,EEF1A2,EPB41L1,NCALD,HPCAL4,DPYSL4,FAM49B,GLS,GNAO1,GPD2,GPM6A,GPM6B,GRIA2,HPCA,L1CAM,MAP2,MAPT,SCAMP5,NCAM1,PDE2A,GNG2,CAMKV,RAB3A,RAB5B,STX1B,NAPB,SNAP25,SNCB,SNCA,STX1A,STXBP1,SYN1,SYP,SYT1,TAF9,TRIM2,VSNL1,XPO1,NDRG4,DPYSL5,CADM2" Interaction int:CYFIP1 CYFIP1 interactions 2.05E-15 2.98E-11 2.71E-12 2.76E-11 77 173 "AP2A1,AP1B1,HECW2,CNTNAP1,APBB1,GAS7,MARK4,WASF1,CAMK2A,CAMK2B,ARHGEF1,ARHGEF2,DCLK1,DLGAP1,NUMBL,SLC4A8,PREPL,CRMP1,NCAN,ERC2,MATR3,DBN1,DNAJC6,DCTN1,SNAP91,DLG2,DLG4,DNM1,NYAP1,DNM2,SHANK1,DPYSL2,ABI1,PDCD6IP,DNM1L,EEF1A2,ABI2,EPB41L1,BAIAP2,AGAP2,SGIP1,DPYSL4,NCKAP1,WASF3,TCERG1,GLUL,LNX1,GRM3,NCKAP1L,SYNPO,TMEM240,KCNB1,KIF2A,MYO5A,NEFH,NTRK2,OPA1,P2RX7,PDE4A,CAMKV,PIK3R1,PRKCB,PRKCG,PROX1,RTN1,SBF1,ARX,MYO16,TNIK,SPTAN1,EPB41L3,NCDN,TPD52L2,LRRC24,TSC1,AMZ1,FXR1" Interaction int:FMR1 FMR1 interactions 7.40E-13 1.08E-08 8.97E-10 9.12E-09 102 281 "CASKIN1,KCNT1,BIN1,LRCH2,USP28,PKP4,APC,CCAR2,DYNLL1,BSN,CACNB2,CACNB4,CAMK2A,CAMK2B,CAMK2D,CAMK2G,LDB2,INA,ARHGEF2,CDC27,MAGI1,DLGAP1,NUMBL,DLGAP3,MAP4K4,NIPBL,HOMER3,CNTN1,MAGED1,NCOR1,NCOR2,ARHGAP24,MATR3,DAPK3,CEP170,PLPPR4,G3BP2,DLG2,DLG4,DNM1,DPYSL2,EIF4G1,ELAVL2,ELAVL3,ELAVL4,EML1,APC2,AGAP2,RGPD5,NBEA,BRSK1,NCKAP1,PRRC2B,IFI16,DOCK7,KCNMA1,KIF2A,KIF5A,KIF5C,KLC1,GIT1,NUMA1,PDE2A,PRKCB,PRKCG,PTPRN2,FAM120C,PBRM1,FBXW7,ATXN2,CASC3,TRA2B,WDR47,SMARCA4,SMARCC2,CDK5RAP2,SNCA,TNIK,KIF21B,UHRF1BP1L,MYCBP2,IQSEC2,SRPK2,STAU1,PRRC2C,MTCL1,CAMSAP2,TBL1X,SMG6,SIN3B,CLASP1,SIK3,TJP1,ICAM5,PARD3,TNR,TNS1,TP53BP1,TSC1,EMSY,PAK5,FXR1" Interaction int:YWHAZ YWHAZ interactions 2.70E-12 3.93E-08 3.02E-09 3.07E-08 172 569 "ARID1A,PLEKHG5,GRAMD1B,ADORA3,KCTD16,CEP126,PPFIA2,KCNAB2,PPFIA3,APP,MADD,ARRB1,MARK4,ATP2B1,ATP2B2,BARD1,KSR1,ARHGEF7,BTRC,CAMK2A,CAMK2B,CAMK2D,CAMK2G,INA,CDK11B,ARHGEF2,CDC25B,DLGAP1,CLTC,FAM189A2,TJP2,HOMER3,ARHGEF6,NSL1,NCOR1,CTNND1,HDAC9,RIPOR2,HDAC4,RASSF2,MATR3,RIMS3,PARD6A,AK5,DLG4,DNM1L,OPTN,EFNB3,APH1A,EGFR,EIF5,EPB41L1,EPB41L2,DMTN,PRMT5,KAT8,MEX3B,FOXO3,EVL,PNMA2,GABBR1,NCKAP1,DISC1,GFAP,FERMT2,LNX1,GP1BB,GSN,PADI2,GABARAPL2,SYNPO,IDH3B,DOCK7,ITPKA,KCNK3,KCNMA1,KIF2A,KIF5C,KLC1,MAP2,MAP6,MAPT,MARK1,MARK3,MBP,MDM4,MEF2C,MOV10,GIT1,ADAM22,MYO5A,NF1,NOS1,PDE1A,PDE1B,PFKFB2,OLA1,PFKP,SSH1,CAMKV,PLEC,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCZ,MAPK7,MAPK8,PTPN13,PTPRO,RAD52,ROGDI,RASGRF2,RGS3,RPRD1A,LRRK2,SBF1,ATXN1,SFPQ,TRA2B,SGK1,MYO18A,SHMT2,CNKSR2,WDR37,SLC1A3,SLC8A2,CCDC88A,MAST1,SOX2,BDP1,UHRF1BP1L,MYCBP2,ERC1,SPTAN1,RBM26,RAP1GAP2,TAB2,ITPRID2,SAMSN1,EPB41L3,STAU1,KLHL7,SYN1,SYN2,CAMSAP2,FBXW11,DMXL2,KIAA0930,RPGRIP1L,WDR7,PSD3,OBSL1,SIK3,PARD3,TNS1,TP53BP1,TP53BP2,SYNPO2,TSC1,TSC2,TUBB2A,UBE3A,CLIP2,KLC2,XPO1,REEP1,WNK1,TUBA1A,WNK2,PAK5,SPATA13" Interaction int:GRIN1 GRIN1 interactions 4.21E-12 6.11E-08 4.37E-09 4.44E-08 52 110 "ACTN2,NUMB,BSN,CALM1,CAMK2A,CAMK2B,CAMK2G,CANX,INA,CDH2,DLGAP1,CLTC,AKAP5,APPL1,CTNND1,DLG2,DLG3,DLG4,GRIN3A,DNM1,DRD1,EPS8,CACNG2,PTK2B,AGAP2,FYN,LNX1,GRIA1,GRIN1,GRIN2D,GRM1,CIT,MAP2,SHC3,NF1,NOS1,PIK3R1,PPP3CA,PPP5C,PRKCB,PRKCG,MAPK3,SHANK2,TNIK,SPTAN1,ARC,TIAM1,TJP1,TP53BP1,KLC2,LRP8,TUBA1A" Interaction int:ARMC1 ARMC1 interactions 5.51E-12 8.02E-08 5.34E-09 5.43E-08 29 44 "APP,CALM1,CAMK2A,CAMK2B,CNTN1,CRMP1,DPYSL2,EPB41L1,EPS8,NCALD,DCTN2,GNAO1,GPM6A,GPM6B,MAP2,MAPT,NCAM1,GNG2,CAMKV,RAB3A,STX1B,SNCB,STXBP1,SYN1,SYN2,SYT1,HSPBP1,VSNL1,DPYSL5" Interaction int:KALRN KALRN interactions 1.67E-11 2.43E-07 1.52E-08 1.55E-07 38 70 "GPRIN1,PKP4,CACNA1A,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,SHISA7,INA,CDH10,DLGAP1,SNCAIP,SIPA1L1,PDE4DIP,CTNND2,DLG2,DLG4,AGAP2,SORBS1,DISC1,LNX1,RAPGEF4,GRIA2,CIT,SYNPO,GIT1,ADAM22,MYO5A,ATXN7,PPP1R9A,CNKSR2,TNIK,SPTAN1,IQSEC2,EPB41L3,DICER1,TRIO" Interaction int:NRXN1 NRXN1 interactions 4.74E-11 6.89E-07 4.05E-08 4.12E-07 26 39 "SYT13,APBA2,CASK,SYT6,DLGAP1,NRXN1,SIPA1L1,DLG4,SDCBP2,GABRA1,NXPH3,NXPH2,SYT9,AFDN,NLGN3,NXPH1,SYTL2,NLGN1,RPH3A,MYO16,PDZD2,ARHGAP26,SYT1,SYT4,SYT5,ATP13A2" Interaction int:CYFIP2 CYFIP2 interactions 7.26E-11 1.06E-06 5.86E-08 5.96E-07 44 91 "AP2A1,CASKIN1,CNTNAP1,APBB1,GAS7,MARK4,WASF1,CAMK2A,CAMK2B,INA,CDH2,CDH10,DLGAP1,HOMER3,APPL1,SRGAP3,DLG4,DNM1,NYAP1,SHANK1,ABI1,ABI2,BAIAP2,AGAP2,NCKAP1,WASF3,TCERG1,PACSIN2,NCKAP1L,KCNMA1,MYO5A,NLGN3,PACSIN1,PTPRE,MYO16,TNIK,MYCBP2,SPTAN1,STAU1,DNMBP,TCF4,TSC1,AMZ1,FXR1" Interaction int:GRIN2B GRIN2B interactions 2.51E-10 3.65E-06 1.92E-07 1.95E-06 45 97 "ACTN2,AP1M1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,AP4M1,CDH2,DLGAP1,CLTC,AKAP5,CTNND1,ARHGAP32,DLG2,DLG3,DLG4,GRIN3A,DNM1,PTK2B,RACK1,AGAP2,FYN,GRIN1,GRM1,CIT,PTPN5,MAP2,SHC3,NF1,NOS1,PIK3R1,PPP3CA,PPP5C,PRKCB,PRKCG,MAPK3,MAGI3,SHANK2,TNIK,SPTAN1,ERBIN,ARC,EXOC7,TUBA1A" Interaction int:DISC1 DISC1 interactions 7.27E-10 1.06E-05 5.29E-07 5.37E-06 56 137 "ACTN2,SPARCL1,CEP126,GPRASP2,PPFIA4,SPTBN4,DST,KALRN,CLU,AKAP6,FEZ1,MATR3,DCTN1,TIAM2,CEP170,SRGAP3,DMD,DYNC1I1,DPYSL2,ASB3,DMTN,KATNAL1,OLFM1,DCTN2,SMC2,DISC1,CIT,KIF3A,MGAT3,MYH7,NEFM,PDE4B,KANSL1,PPP5C,ANKHD1,ROGDI,FBXW7,ITSN1,PPM1E,SYBU,ZNF365,CDK5RAP3,CCDC88A,ATF7IP,SMARCE1,MYT1L,TNIK,SPTAN1,EXOC7,AGTPBP1,SYNE1,FRYL,TRIO,TUBB2A,CCDC136,TFIP11" Interaction int:FXR1 FXR1 interactions 1.24E-09 1.80E-05 8.55E-07 8.69E-06 77 216 "AP2A1,AP2A2,CEP126,MYH7B,PPFIA3,CCAR2,DYNLL1,ARHGEF7,CAMK2A,CAMK2B,INA,ARHGEF2,CDH2,DLGAP1,LRWD1,EPS15L1,CLU,MAP4K4,CRMP1,NCOR1,NCOR2,SEC24C,PDE4DIP,GPRASP1,GIT2,MYEF2,CEP170,SEC16A,EXOG,FARSB,ELAVL2,ELAVL4,PLEKHO1,BAIAP2,RGPD5,ANKFY1,NOP56,ZNF512,GOLGB1,PRRC2B,TUBA1C,DIDO1,GRIK3,HNRNPK,IFI16,DOCK7,KIF2A,AFDN,GIT1,HNRNPM,RCOR2,PAK3,CDK18,RDX,KIF7,CLIP1,SBF1,KIF21A,ITSN1,WDR47,CCDC88A,SPHKAP,SMARCA4,SMARCC2,SNCA,TNIK,MYCBP2,SRPK2,EPB41L3,PRRC2C,DNAJC9,TNR,TP53BP1,TSC1,TTC3,FXR1,SPATA13" Interaction int:HAX1 HAX1 interactions 2.59E-09 3.77E-05 1.71E-06 1.74E-05 56 141 "AMPH,ANK2,DGKD,CALB2,CAMK2A,CAMK2B,DCLK1,CLU,CNTN1,CRMP1,KIAA0513,SNAP91,NTM,DNM1,DPP6,DPYSL2,DNM1L,EDIL3,TNK2,EPB41L1,NCALD,TUBB4A,DPYSL4,IQGAP2,GNAO1,GPD2,GPM6A,GPM6B,TUBA1C,GRIA2,HNF4G,HPCA,L1CAM,MAP2,MAPT,NCAM1,GNG2,ABCB1,CAMKV,PPP3CC,MAPK10,RAB3A,STX1B,NAPB,SNCA,STX1A,STXBP1,SYN1,SYN2,SYP,SYT1,CDK20,VSNL1,XPO1,NDRG4,DPYSL5" Interaction int:PEX5L PEX5L interactions 4.47E-09 6.50E-05 2.83E-06 2.87E-05 26 45 "ADD1,SLC12A5,AP2A1,AP2A2,CASKIN1,KCTD16,SLC4A4,HCN2,CAMK2A,ARHGEF2,CDH2,NCAN,CTNND2,DBN1,NCKAP1,GIT1,MYO5A,HCN1,PEX5,TNIK,SPTAN1,WDR7,ICAM5,PARD3,TNR,PPP1R3F" Interaction int:DLG1 DLG1 interactions 4.96E-09 7.21E-05 3.01E-06 3.05E-05 46 108 "ACTN2,BEGAIN,CASK,ATP2B2,ADGRB1,BTRC,CAMK2A,DLGAP2,DLGAP1,DLGAP3,AKAP5,GDA,DLG2,DLG3,DLG4,EFNB3,EPB41,ERBB4,CACNG2,AGAP2,ADGRA3,GRIA1,GRIK2,GRIN1,GUCY1A2,TJAP1,KCNA1,KCNA2,KCNA4,KCNC1,KCNJ4,KCNJ10,MPP2,MYO6,NRCAM,HCN1,PAX6,PTPRE,MAPK12,CNKSR2,TNIK,KIF1B,WWC1,UBE3A,AMOT,KCNAB1" Interaction int:CAMK2A CAMK2A interactions 5.25E-09 7.64E-05 3.06E-06 3.10E-05 43 98 "ACTN1,ACTN2,LRRC7,ATP2A2,MPDZ,CDK5R1,CDK5R2,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DLGAP1,RCHY1,PDE4DIP,ARHGAP32,DCTN1,DLG3,DLG4,EGFR,CACNG2,AGAP2,DCTN2,NCKAP1,GFAP,GNAO1,GRIN1,HNRNPK,HSP90AA1,ITPKA,KCNC1,CAMK2N2,MAPT,GIT1,NOS1,HCN1,CNKSR2,RIMS1,TNIK,MYCBP2,TSC1,SSBP2,FXR1" Interaction int:ATXN1 ATXN1 interactions 8.90E-09 1.29E-04 4.98E-06 5.06E-05 86 260 "ADCY6,ADD3,APBB1,KCNAB2,SEMA4G,ATP1A3,CAMK2B,ENTPD6,NUMBL,PLEKHB1,KIAA1549L,QKI,CREM,CRY2,NCOR1,NCOR2,CST3,DZIP3,PUM1,PPP6R2,ARHGAP32,HDAC4,TBC1D5,IST1,TOMM20,ZNF804A,MYEF2,POM121,SV2A,DMPK,HEYL,SUGP2,UBE2E3,FYN,AHDC1,ZNF276,PRRC2B,NUDT21,RAPGEF4,RAPGEF1,CLASRP,C1orf94,ZHX1,ATXN2L,ACOT7,USP54,MATN2,MBP,NCAM1,OPCML,KCTD15,CDIP1,VSTM2L,QRICH1,ANKHD1,FAT4,YY1AP1,BAALC,ST6GALNAC6,ATXN1,ATXN2,SUPT20H,MYO18A,R3HDM2,SYBU,SMARCC2,ZHX3,ZSWIM8,UHRF1BP1L,RBM26,STAC2,MLST8,TBX15,HEY2,R3HDM1,RBFOX2,IL34,ELP5,TSC1,EIF4ENIF1,CCDC136,VSNL1,SF1,WNK1,WNK2,KAT6A" Interaction int:NLGN1 NLGN1 interactions 5.72E-08 8.31E-04 3.08E-05 3.13E-04 10 10 "NRXN3,NRXN1,NRXN2,B3GAT3,DLG2,DLG3,DLG4,AGAP2,NLGN3,NLGN1" Interaction int:PDE4DIP PDE4DIP interactions 1.69E-07 2.45E-03 8.76E-05 8.90E-04 90 292 "GPR158,CASKIN1,AMPD2,CCDC146,PKP4,PPFIA3,DYNLL1,WASF1,KALRN,CAMK2A,CAMK2B,CDH2,CDH10,LRRFIP1,CLU,MAP4K4,HOMER3,ARMC8,RGS6,CSNK1E,OSBPL3,PDE4DIP,DZIP3,ERC2,ARHGAP32,HDAC4,MATR3,ARMCX4,JAKMIP2,CEP170,ARNT2,SHANK1,DPYSL2,FRY,ELAVL2,ELAVL3,ELAVL4,CAMSAP1,FHL1,AGAP2,NBEA,GATM,CIT,KIF2A,GIT1,JAKMIP3,CCDC13,NF1,KSR2,PDE4D,A2ML1,ZFYVE21,JAKMIP1,PRKACB,PRKCB,PRKCG,PTPRN2,FAM120C,C1orf109,RDX,KIF7,CLIP1,WDR47,CCDC88A,RTP5,ATF7IP,CDK5RAP2,SNCA,TNIK,KIF21B,SPTAN1,SRPK2,CLASP2,KLHL7,SYNE2,ANKRD28,ZEB1,CLASP1,ARHGEF12,PARD3,TNR,TP53BP1,TP53BP2,VGF,CLIP2,ZBTB38,ZSCAN26,TFIP11,STOX2,FXR1" Interaction int:YWHAB YWHAB interactions 1.80E-07 2.62E-03 9.04E-05 9.19E-04 117 407 "AMPD2,PPFIA1,ALS2,APP,ARRB1,ARRB2,MARK4,DOCK11,BID,KSR1,ARHGEF7,BTRC,FOXK1,CAMK2A,CAMK2B,CDK11B,ARHGEF2,CDC25B,DLGAP1,FAM189A2,TJP2,SLC4A7,OSBPL3,PUM1,DOCK4,GAPVD1,HDAC4,RASSF2,TBC1D5,DAPK1,CEP170,WDR20,DLG4,DYRK1A,DNM1L,OPTN,EGFR,EPB41,EPB41L1,DMTN,DENND4A,RRAGB,TESK2,FER,BAIAP2,MEX3B,AGAP3,FOXO3,SORBS1,RAPGEF6,NCKAP1,RNPS1,LNX1,FRMD5,USP54,KCNJ11,KCNK3,KCNMA1,KLC1,MAPT,MARK1,MARK3,MDM4,AFDN,ADAM22,NCAM1,NF1,CDK18,PDE3B,PFKFB2,CDK14,SSH1,PIK3C2A,PPP5C,PRKCG,PRKCZ,MAPK7,PTPN13,RASGRF1,RGS3,RGS7,LRRK2,RTKN,R3HDM2,SLC8A2,SLC8A1,RADIL,SLC8A3,MAST1,SNCA,SON,UHRF1BP1L,MYCBP2,SPTAN1,KIF1B,SRPK2,CLASP2,SAMSN1,EPB41L3,MPRIP,WWC1,FBXW11,KIAA0930,CLASP1,TNS2,FRYL,SIK3,R3HDM1,PARD3,TP53BP2,TSC1,TSC2,KLC2,RICTOR,WNK1,FRMD6,SPATA13" Interaction int:GRIN2A GRIN2A interactions 2.42E-07 3.52E-03 1.17E-04 1.19E-03 23 43 "ACTN1,CASK,AP1M1,CAMK2A,CAMK2B,AP4M1,DLGAP1,ARHGAP32,DLG2,DLG3,DLG4,GRIN3A,EPS8,PTK2B,AGAP2,FYN,GRIA1,GRIN1,GRIN2C,PTPN5,RGS3,TNIK,SPTAN1" Interaction int:PRKACA PRKACA interactions 2.57E-07 3.74E-03 1.21E-04 1.23E-03 87 282 "ASIC1,ACLY,ADCY5,ADD1,ADD2,ANXA7,APC,DYNLL1,SLC4A4,ATP2B1,WASF1,BTRC,CACNB2,ASIC3,CLTC,AKAP7,AKAP5,CREM,PDE4DIP,KLHL3,DRD1,DYRK1A,SH3GLB1,EGFR,DMTN,ETV1,CACNG2,PPP1R1B,AGAP2,EVL,C2orf88,CAMKK2,GABRB3,GAD1,GAD2,GCK,GFAP,GJB1,GP1BB,CNTRL,STMN2,GRIA1,GRIA4,GRIN1,NR3C1,HMGCR,HSP90AA1,ITPKA,ITPKB,KCNH2,STMN1,MAP2,MAPT,MBP,MOV10,NASP,NOS1,PDE3A,PDE3B,PDE4B,PDE4D,PDPK1,PFKFB2,PLIN1,FXYD1,PRKACB,PKIA,PRKAR1B,PTPN13,RAP1GAP,RASGRF1,RGS10,RPE,RYR1,SBF1,CCDC88A,CDK5RAP2,SNAP25,TNIK,SYN1,SYN2,FBXW11,SIK3,GPR161,TPD52,UBE3A,XPO1" Interaction int:YWHAH YWHAH interactions 5.57E-07 8.10E-03 2.53E-04 2.57E-03 76 241 "PLEKHG5,CC2D2A,OGT,ARRB1,ARRB2,MARK4,NCOA1,ALDH7A1,ARHGEF2,CDC25B,DLGAP1,CHRNA4,HOMER3,SNCAIP,RIMS2,NOS1AP,HDAC4,RASSF2,RUSC2,CEP170,PARD6A,WDR20,OPTN,EIF5,EPB41L2,MEX3B,FOXO3,FERMT2,CNTRL,NR3C1,RASSF8,FRMD5,HNRNPK,DOCK7,KCNH2,KCNK3,KCNMA1,MAPT,MARK1,MARK3,MDM4,PTOV1,NEK1,NF1,PDPK1,SSH1,MED1,PRKCZ,MAPK7,PTH1R,ZC3H14,LRRK2,FAM192A,RPH3A,CCDC88A,MAST1,RIMS1,SNCA,MYCBP2,KIF1B,SAMSN1,EPB41L3,WWC1,KIAA0930,RPGRIP1L,TNS2,FRYL,SIK3,THRA,PARD3,TP53BP2,TSC1,TSC2,XPO1,FRMD6,SPATA13" Interaction int:GABRA1 GABRA1 interactions 6.33E-07 9.20E-03 2.79E-04 2.83E-03 16 25 "CANX,NRXN1,GPHN,NBEA,GABRA1,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,OS9,NLGN3,PPP3CA,PRKCG" Interaction int:HCN1 HCN1 interactions 7.13E-07 1.04E-02 3.05E-04 3.10E-03 22 42 "ASIC1,KCTD16,MPDZ,HCN2,ARHGEF7,BSN,CAMK2A,CAMK2B,DSCAM,GPHN,CIT,GIT1,NF1,HCN1,PAK3,SH3KBP1,PRKAR1B,RPH3A,SPHKAP,TNIK,MAPK8IP3,TNS1" Interaction int:DNM1 DNM1 interactions 9.90E-07 1.44E-02 4.11E-04 4.18E-03 38 96 "AP2A2,CEP126,AMPH,BIN1,ARRB1,DLGAP1,CLTC,DNM1,DNM2,DYRK1A,SH3GLB1,PTK2B,RACK1,FER,AGAP2,NCKAP1,GRIN1,GRIN2D,PACSIN2,KCNMA1,KIF2A,KIF5A,PIK3R1,PACSIN1,SH3KBP1,RPE,SCN2B,ITSN1,SH3GL2,SH3GL3,SNAP25,TNIK,FNBP1,DNMBP,CABIN1,TBC1D15,LYPD6,TUBA1A" Interaction int:PATJ PATJ interactions 1.66E-06 2.41E-02 6.69E-04 6.79E-03 31 73 "PLEKHG5,ADGRB1,CAMK2A,CAMK2B,ASIC3,NRXN2,HOMER3,GDA,CACNG2,BAIAP2,AMOTL2,TUBA1C,GRIN2C,GRIN2D,HSF2,HTR2A,KCNA4,KCNJ10,PAX6,PPP3CA,PRKCB,MAPK12,CNKSR2,SNCA,KIF1B,WWC1,PCDHAC2,PARD3,TUBB2A,AMOT,TUBA1A" Interaction int:AP2A1 AP2A1 interactions 1.94E-06 2.82E-02 7.63E-04 7.76E-03 46 128 "AP2A1,AP2A2,AP1B1,AMPH,BIN1,ARRB1,ARRB2,NUMB,SYNJ1,REPS2,CLTB,CLTC,PPP6R2,DBN1,SEC16A,DNM2,DPYSL2,EGFR,AGAP2,SYT3,STAMBP,NCKAP1,GHR,RUNDC3A,LNX1,SYNPO,L1CAM,SMAD9,MYO6,OCRL,ANLN,EPN1,SLC25A41,FBXW7,ARX,MYO18A,ARFGAP1,SNAP25,TNIK,FCHO1,MMS19,OBSL1,TMPO,UBC,XPO1,FXR1" Interaction int:ATXN1L ATXN1L interactions 2.23E-06 3.24E-02 8.52E-04 8.66E-03 29 67 "ADORA1,APBB1,GAS7,CBFA2T2,FADS2,PICK1,NCOR1,NCOR2,SUGP2,EPB41L2,TMEM8B,PRRC2B,CLASRP,TMEM25,ACOT7,USP54,MATN2,MBD1,ANKHD1,YY1AP1,ST6GALNAC6,ATXN1,SMARCC2,ZSWIM8,EPB41L3,STAC2,CAMSAP2,RBFOX2,ELP5" Interaction int:PRKCG PRKCG interactions 2.37E-06 3.44E-02 8.82E-04 8.96E-03 33 81 "ANXA7,APP,MARK4,NUMB,ARHGEF25,CDC42,DLGAP1,FBXO7,PICK1,PDE4DIP,PARD6A,DLG4,EPHB1,AGAP2,PDLIM5,GABRA1,GABRA4,GFAP,LNX1,GRIA4,GRIN1,GRIN2D,GRM5,HSP90AA1,NRGN,PRKCG,SCN3A,CNKSR2,TNIK,STXBP1,TIAM1,PARD3,TSC1" Interaction int:YWHAE YWHAE interactions 2.46E-06 3.57E-02 8.83E-04 8.97E-03 144 548 "SYN3,ACLY,RBM10,PLEKHG5,OGT,LRCH2,SHROOM2,ARRB1,ARRB2,MARK4,ALDH7A1,KSR1,BTRC,CALM1,BRSK2,CBR1,INA,CDK11B,ARHGEF2,CDC25B,DCLK1,ARHGAP33,DLGAP1,DLGAP3,CLTC,FAM189A2,HOMER3,RCHY1,CRY2,NCOR2,OSBPL3,ERC2,CTNND1,RIMS2,RUBCN,HDAC9,HDAC4,RASSF2,RIMS3,GIT2,DBN1,CEP170,SRGAP3,DLG4,DYRK1A,DNM1L,EEF1A2,APH1A,EIF5,DMTN,DENND4A,KAT8,FGF12,BAIAP2,MEX3B,CAP2,FOXO3,MSANTD4,BRSK1,DISC1,SPIN1,DCLK2,FERMT2,GRB10,RASSF8,DOCK7,TUBB2B,KCNH2,KCNK3,KCNMA1,KIF5A,KLC1,MAPT,MARK1,MARK3,MDM4,AFDN,GIT1,DBNL,NF1,CDK18,PFKFB2,CDK14,SSH1,PPM1B,PRKCG,MAPK7,PRPSAP2,RAD52,RAP1GDS1,RASGRF1,RGS3,LRRK2,ATAT1,ATXN1,SFPQ,TRA2B,SHMT2,R3HDM2,WDR37,SLC8A2,SLC8A1,SLC8A3,CCDC88A,MAST1,SNCA,KIF21B,ERC1,KIF1B,RAP1GAP2,CLASP2,ITPRID2,SAMSN1,EPB41L3,MPRIP,SYN1,SYN2,WWC1,FBXW11,KIAA0930,RPGRIP1L,CLASP1,OBSL1,TNS2,CRTC1,SIK3,TIAM1,ACTR6,TMPO,PARD3,TP53BP2,TSC1,TSC2,TUBB2A,UBE3A,KLC2,XPO1,REEP1,POLR3H,WNK1,TUBA1A,DOCK8,HNRNPA3,SPATA13" Interaction int:CNKSR2 CNKSR2 interactions 2.49E-06 3.62E-02 8.83E-04 8.97E-03 25 54 "LRRC7,ARHGEF7,KALRN,CAMK2A,CAMK2B,INA,DLGAP1,SNAP91,DLG2,DLG3,DLG4,BAIAP2,AGAP2,GLUL,GNAO1,GIT1,PRKACB,PRKCG,RGS3,CNKSR2,TNIK,SPTAN1,SYT1,TJP1,TNR" Interaction int:CALM1 CALM1 interactions 2.96E-06 4.30E-02 1.02E-03 1.04E-02 93 323 "ACADM,ADCY8,ADCYAP1R1,ADD1,ADD2,ADRB2,PLA2G6,AMPH,BIN1,ATP2B1,DOCK11,DST,ARHGEF7,SCAPER,CALM1,CAMK2G,MYL6B,CLTB,AKAP6,AKAP5,RCHY1,MATR3,DAPK1,DBN1,ZBTB24,DLG3,CASP8AP2,DNM1L,OPTN,EGFR,FECH,FER,DCTN2,USP16,CAMKK2,IQGAP2,GAP43,GJB1,GNAS,GRK4,GRIN1,NR3C1,GRM3,GRM5,GRM7,OPALIN,HSP90AA1,MYLK2,ITPKA,ITPKB,JAK2,KCNB1,KCNH1,KCNN2,KCNN3,KCNQ2,KCNQ3,MAPT,MOV10,MYBPC1,MYO7A,NEUROD1,NRGN,PDE1A,PHKG1,ANLN,PLCD1,STRN3,PTAFR,CEP97,RDX,RGS4,RGS10,RIT2,LRRK2,CLIP1,RYR1,S100B,SH3GL2,MYO18A,SNCA,MYCBP2,SPP1,KIF1B,SYNE2,SYT1,TCF4,CABIN1,TRPC3,TSC2,UBE3A,CCDC14,XRCC4" Interaction int:KHDRBS1 KHDRBS1 interactions 3.10E-06 4.50E-02 1.03E-03 1.05E-02 58 177 "SNX30,AMPH,APBB1,GAS7,RIPK1,BTK,PTBP2,CD81,RBM39,CRY2,ARHGEF4,MATR3,YTHDC1,RUSC2,DLG2,DLG3,DLG4,DOCK2,ABI2,GPHN,SRRM1,SH3YL1,TUBB3,EFEMP1,FGR,SYNCRIP,SORBS1,KHDRBS3,MPP6,FYN,PACSIN2,ATXN2L,HNRNPK,KCNMA1,MIA2,MYO7A,PIK3R1,PACSIN1,SH3KBP1,PTCH1,KHDRBS2,LGR4,ATXN2,SFPQ,SCG5,ITSN1,SRPK2,ITPRID2,ARHGEF9,DNMBP,FBXW11,TBL1X,OBSL1,TJP1,RBFOX2,VAV1,SMARCAD1,SPATA13" Interaction int:HOMER1 HOMER1 interactions 3.12E-06 4.54E-02 1.03E-03 1.05E-02 35 89 "BIN1,SPTBN4,WASF1,KALRN,CAMK2A,DLGAP1,HOMER3,PDE4DIP,SIRPA,DBN1,DNM1,SHANK1,EEF1A2,AGAP2,GRIA1,GRIK1,GRIN1,GRM1,GRM5,DOCK7,KIF5C,DBNL,NCAM1,C19orf57,PPP3CA,RYR1,SHANK2,TNIK,SPTAN1,NCDN,FRYL,TNR,TP53BP2,TPM1,TRPC1" Interaction int:KCNA2 KCNA2 interactions 3.60E-06 5.24E-02 1.16E-03 1.18E-02 14 22 "CNTNAP1,KCNAB2,DLGAP1,CNTNAP2,DLG4,ETV1,PTK2B,FYN,KCNA1,KCNA2,KCNA4,KCNB1,KCNAB1,RTN4" Interaction int:DLG2 DLG2 interactions 4.22E-06 6.13E-02 1.33E-03 1.36E-02 24 52 "DYNLL1,ATP2B2,KALRN,DLGAP1,DLG2,DLG3,DLG4,ERBB4,CACNG2,AGAP2,GRID1,GRIN1,GRIN2D,GUCY1A2,KCNA4,KCNJ4,NOS1,NLGN3,MAPK12,CNKSR2,NLGN1,TNIK,MYCBP2,KIF1B" Interaction int:DLG3 DLG3 interactions 6.07E-06 8.82E-02 1.88E-03 1.91E-02 33 84 "APC,ATP2B2,CALM1,CAMK2A,RHBDL1,DLGAP1,DLGAP3,GDA,DLG2,DLG3,DLG4,DYNC1I1,ERBB4,CACNG2,PTK2B,AGAP2,GRIK2,GRIK5,GRIN1,GRIN2C,GUCY1A2,TJAP1,KCNA4,NLGN3,MAPK12,CNKSR2,NLGN1,ARFGAP1,TNIK,KIF1B,EXOC7,ZFP91,KCTD2" Interaction int:AMPH AMPH interactions 7.15E-06 1.04E-01 2.17E-03 2.20E-02 23 50 "AP2A1,AP2A2,AP1B1,AMPH,BIN1,CDK5R1,SYNJ1,CALM1,REPS2,CLTC,DNM1,DNM2,DYRK1A,SH3GLB1,TNK2,SGIP1,PPP3CC,PTK2,ITSN1,SH3GL2,SH3GL3,SYN1,CABIN1" Interaction int:ITSN2 ITSN2 interactions 7.50E-06 1.09E-01 2.20E-03 2.23E-02 35 92 "AGT,SEMA6A,LTBP4,AMPH,MAP4K3,DST,SYNJ2,DLGAP1,EPS15L1,PDE4DIP,TM9SF4,DNM2,PDCD6IP,GOLT1B,EGFR,MEGF10,AHDC1,GOLGB1,HNRNPK,GAREM2,ITPKA,PIK3AP1,MBNL1,SH3KBP1,PTN,ITSN1,PPP4R3A,ERC1,SYN1,TACC1,NR2C2,TRIO,UBC,WIPF1,WIPF2" Interaction int:CAMK2G CAMK2G interactions 7.56E-06 1.10E-01 2.20E-03 2.23E-02 28 67 "ACTN2,LRRC7,CALM1,KALRN,CAMK2A,CAMK2D,CAMK2G,DLGAP1,RCHY1,CREM,DBN1,EGFR,AGAP2,PDLIM5,USP19,MALT1,GRIA1,GRIA4,GRIN1,SYNPO,HSP90AA1,STMN1,ANLN,RYR1,TNIK,SYN1,TIAM1,TSC1" Interaction int:GSK3B GSK3B interactions 8.20E-06 1.19E-01 2.34E-03 2.38E-02 92 326 "ACLY,AXIN2,HECW2,MRTFA,OGT,APC,APP,SPTBN4,ARRB1,ARRB2,DYNLL1,BTRC,ENTPD6,FBXO7,CREM,SNCAIP,CSF3R,CTNND1,CTNND2,HDAC4,DBI,DCTN1,MED24,DYNC1I1,DPYSL2,RCAN1,DUSP9,DNM1L,PLEKHO1,RCAN2,EYA1,ACTL6B,AGAP2,IQCG,FOXM1,DCTN2,UFM1,OGA,DKK3,NCKAP1,DISC1,PPARGC1A,COPS8,ADAP1,TPPP,IGSF21,ZHX1,HSP90AA1,RBPJ,SMAD1,MAP4,MAPT,MITF,NFE2L2,HCN1,PDE4D,PFKFB4,PPP3CC,PRKCB,PRKCZ,MASP1,PTK2,PTN,RNF220,FBXW7,LRRK2,RXRA,ASRGL1,SGK1,ANKRD6,SLA,SNCA,TNIK,SOX10,BEX1,TAB2,CLASP2,EPB41L3,NSFL1C,ACSBG1,FBXW11,TSC1,TSC2,SGK3,UBE3A,MICAL1,RICTOR,XPO1,UPF3A,TUBA1A,EPM2A,FXR1" Interaction int:KCNA4 KCNA4 interactions 9.04E-06 1.31E-01 2.51E-03 2.55E-02 15 26 "ACTN2,KCNAB2,CASK,DLGAP1,DLG2,DLG3,DLG4,FYN,LNX1,KCNA1,KCNA2,KCNA4,SNTG1,ERBIN,SIRT1" Interaction int:ADRB1 ADRB1 interactions 9.14E-06 1.33E-01 2.51E-03 2.55E-02 12 18 "GPRASP2,ARRB1,ARRB2,DLGAP2,GPRASP1,MAGI2,DLG4,NOS1,SH3GL2,SH3GL3,MAGI3,GOPC" Interaction int:ADGRB1 ADGRB1 interactions 1.26E-05 1.83E-01 3.39E-03 3.45E-02 13 21 "LRRC7,ARRB2,ADGRB1,BAIAP3,MAGI1,PHYHIP,ELMO1,MAGI2,DLG4,ERBB2,BAIAP2,MAGI3,PDZD2" Interaction int:STARD13 STARD13 interactions 1.48E-05 2.16E-01 3.92E-03 3.98E-02 20 42 "LRFN1,ADGRB2,KSR1,DCLK1,MAGI1,SIPA1L1,HDAC4,KCTD3,EPB41L1,TUBA1B,TESK2,ZNF638,HMGCR,HSP90AA1,SMAD1,NF1,RTKN,SMARCD3,KIF1B,TUBA1A" Interaction int:RAC1 RAC1 interactions 1.57E-05 2.28E-01 4.07E-03 4.13E-02 71 240 "ABR,HACE1,LTBP4,ARHGDIA,ARHGDIG,SYNJ2,ARHGEF7,WASF1,CALM1,KALRN,ARHGEF25,USP6,ARHGEF2,ARHGAP33,MAGI1,DLGAP1,CHN1,CHN2,ARHGAP22,MYL6B,CLTC,ARHGEF6,ARHGEF4,CYBB,ARHGAP32,BRINP1,PARD6A,DLG4,DMPK,DOCK2,TOM1,USH1C,BAIAP2,AGAP2,NCKAP1,IQGAP2,GRIN1,CIT,HNRNPK,KTN1,GIT1,NCF2,OCRL,OPHN1,PAK3,PIK3R1,PKM,PLXNB1,PSAT1,PPP2R2B,PTK2,RAP1GDS1,RASGRF1,LRRK2,CLIP1,SFPQ,SH3BP2,TNIK,IQSEC2,STAU1,MCF2L,TCF7L2,TIAM1,TRIO,TSC1,VAV1,VAV2,HPS4,DOCK8,UBE3B,PAK5" Interaction int:LIN7C LIN7C interactions 1.60E-05 2.32E-01 4.07E-03 4.13E-02 23 52 "PLEKHG5,CASKIN1,PPFIA2,PPFIA1,APC,PPFIA3,CASK,MPDZ,NRXN1,SPATA2,DLG3,BAIAP2,AMOTL2,MPP6,ABLIM2,KCNJ4,KCNMA1,MPP2,SLC25A41,FOXRED2,WWC1,AMOT,XPO1" Interaction int:CACNG2 CACNG2 interactions 1.69E-05 2.45E-01 4.23E-03 4.30E-02 15 27 "APP,CAMK2A,CCNT1,CSNK1E,DLG2,DLG3,DLG4,CACNG2,HBS1L,GRIA1,GRIA2,GRIA4,GRIN1,SRPK2,GOPC" Interaction int:WASL WASL interactions 1.75E-05 2.54E-01 4.26E-03 4.33E-02 27 66 "BIN1,APBB1,APP,ASPA,BCHE,WASF1,CDC42,ABI1,EGFR,ABI2,SORBS3,BAIAP2,WASF3,ZNF638,GSN,ATG4C,PACSIN2,HP,HSP90AA1,IPO5,PACSIN1,SH3KBP1,ITSN1,FNBP1,DNMBP,WIPF1,WIPF2" Interaction int:SHANK2 SHANK2 interactions 1.76E-05 2.56E-01 4.26E-03 4.33E-02 17 33 "DYNLL1,ADGRB2,ARHGEF7,DLGAP2,DLGAP1,DLGAP3,DLG4,DNM2,EGFR,BAIAP2,AGAP2,GRIN1,MYO5A,SHANK2,TNIK,SSTR2,XPO1" Interaction int:MYCBP2 MYCBP2 interactions 1.82E-05 2.64E-01 4.33E-03 4.40E-02 62 203 "UNC79,LRCH2,APC,SHTN1,ZSCAN18,CALM1,CAMK2A,CAMK2B,ARHGEF2,DCLK1,LRRFIP1,MAP4K4,AKAP12,CRY2,TBC1D5,MATR3,DAPK1,DBN1,DCTN1,MYEF2,G3BP2,DLG2,RACK1,SYT3,SORBS1,NEURL4,LNX1,GSN,GUCY1B1,DOCK7,SESN3,TAGLN3,CTNNA3,ALDH1L2,PDE1B,SSH1,IQSEC3,ROBO2,FBXW7,LGR4,PPP1R9A,SEC31A,ABLIM3,SMARCC2,LIMCH1,TNIK,KIF21B,MYCBP2,SPTAN1,SRPK2,CLASP2,MPRIP,PRRC2C,SYNE2,CLASP1,PCDHA3,ATP13A2,HEY1,TJP1,UBE3A,NSD2,FXR1" Interaction int:NEFL NEFL interactions 2.03E-05 2.95E-01 4.75E-03 4.83E-02 28 70 "APP,MTMR2,KALRN,USP2,DLGAP1,PDE4DIP,PPP1R16B,SEC16A,DLG4,AGAP2,NCKAP1,GRIN1,KCNMA1,KIFC3,MAP2,MYO5A,NEFM,NEFH,CNKSR2,CDK5RAP2,SPTAN1,TRIM2,OBSL1,TSC1,SYNC,RSPRY1,FXR1,GAN" Interaction int:PTPRA PTPRA interactions 2.07E-05 3.01E-01 4.77E-03 4.85E-02 26 63 "CALM1,CANX,EGFR,EPB41L1,ERBB2,DENND4A,BAIAP2,FYN,GAB1,GABARAPL2,KCNA2,KCNMA1,MBP,PSAT1,PRKCB,PTPRD,PTPRE,PTPRG,ATXN2,PPP4R3A,CCDC88A,SP4,NCDN,TPCN2,PSD3,GPRIN3" Interaction int:SYT3 SYT3 interactions 2.14E-05 3.11E-01 4.86E-03 4.94E-02 10 14 "AP2A1,MADD,SYT6,SYNCRIP,SYT3,MYH7,FNDC3A,SNAP25,MYCBP2,SYT5" Interaction int:GNB1 GNB1 interactions 2.70E-05 3.93E-01 6.04E-03 6.14E-02 40 116 "ADRB2,ARRB1,BTK,CACNA1A,CACNA1B,KALRN,DLGAP1,COX4I1,RGS6,HDAC4,DLG4,DYNC1I1,DUSP9,APH1A,RACK1,FGFR1,AGAP2,FYN,DISC1,GNAO1,GNAS,GNG3,GNG4,NR3C1,SYNPO,KCNJ3,NCF2,GNG2,PIK3R1,PTH1R,PTK2,RIC8B,CNKSR2,RADIL,MCF2L,PIK3R5,RASD2,UBC,RICTOR,XPO1" Interaction int:NCKAP1 NCKAP1 interactions 2.82E-05 4.10E-01 6.21E-03 6.31E-02 31 82 "AP2A1,GAS7,WASF1,CAMK2A,DLGAP1,HOMER3,DLG4,DNM1,NYAP1,DPYSL2,ABI1,ABI2,EPB41L1,BAIAP2,CAP2,AGAP2,SGIP1,NCKAP1,WASF3,SYNPO,PIK3R1,SNAP25,MYO16,TNIK,SPP1,SPTAN1,EPB41L3,DNMBP,TCF4,TSC1,AMZ1" Interaction int:LNX2 LNX2 interactions 3.48E-05 5.05E-01 7.45E-03 7.57E-02 34 94 "PLEKHG5,NUMB,SLC4A4,ATP2A2,USP2,NUMBL,SRSF11,NRXN1,ERC2,CTNND2,C2CD2L,OPTN,IP6K2,AGAP2,IGSF5,FERMT2,LNX1,GRIA2,KCNJ10,KIF5A,MDGA1,NOMO2,PDZRN4,PPP3CA,PRKAR1B,MAPK9,KLHL11,SLC6A1,SPHKAP,PDZRN3,ERC1,PEG10,KAZN,MSRB3" Interaction int:LNX1 LNX1 interactions 3.48E-05 5.06E-01 7.45E-03 7.57E-02 102 382 "CPNE2,ABR,CLK4,NDRG3,NDRG2,PLEKHG5,ADD1,ADRA1D,AP2A1,AP1B1,C1QTNF1,PPFIA2,PPFIA1,PKP4,PPFIA3,APP,SHTN1,CDK13,NUMB,RASL11B,ATP2B3,MTMR9,WASF1,CA8,KALRN,CAMK2D,ENTPD2,NUMBL,SOCS6,LRRC3B,DZIP3,ERC2,CTNND2,ACY3,DAPK1,DTNA,ATL1,ERBB2,WAC,CAMSAP1,KHDRBS3,NEK6,IGSF5,FERMT2,LNX1,GRIN1,CIT,HSP90AA1,METTL21A,KCNA4,CAMK2N2,VWA5A,KCTD6,MID1,NRCAM,CDK14,ABCB1,PKM,PDZRN4,NECAB2,PPP3CA,PRKAR1B,PRKCG,MAPK9,PRPH,RAD51D,ENOX1,SLC6A15,DPF2,KCTD17,KIF7,KLHL11,CCDC102B,HUNK,HSPA4L,FBXO11,SLC1A3,SLC6A1,SPHKAP,SNCB,PDZRN3,MYCBP2,ERC1,ZBTB43,PBLD,NXT2,INKA2,STAC2,PHLDB1,DNAJC9,KAZN,ROBO3,TBCEL,DOCK9,FAM124A,TPM4,TSC2,HEPACAM,OSBP2,ZNF24,TRIM9,MVB12B" Interaction int:GRIA1 GRIA1 interactions 3.91E-05 5.68E-01 8.23E-03 8.36E-02 19 41 "CAMK2G,CANX,DLGAP1,PICK1,DLG4,EPB41L1,EPB41L2,EPS8,CACNG2,AGAP2,GRIA1,GRIA2,GRIA4,GRIK2,GRIN1,GRIN2C,MYO5A,TNIK,TRPC1" Interaction int:PAK3 PAK3 interactions 4.29E-05 6.24E-01 8.91E-03 9.06E-02 12 20 "ARHGEF7,CDC42,ARHGEF6,GIT2,GIT1,MYO6,HCN1,PAK3,ITSN1,SNCA,SYN1,FXR1" Interaction int:IQSEC3 IQSEC3 interactions 4.83E-05 7.02E-01 9.88E-03 1.00E-01 7 8 "DLGAP1,MAGI2,DMD,AGAP2,IQSEC3,TNIK,MYCBP2" Interaction int:ERC2 ERC2 interactions 4.89E-05 7.11E-01 9.88E-03 1.00E-01 13 23 "PPFIA4,PPFIA2,PPFIA1,PPFIA3,BSN,PDE4DIP,ERC2,LNX1,PCLO,GIT1,RIMS1,TNIK,ERC1" Interaction int:ERBIN ERBIN interactions 4.97E-05 7.22E-01 9.89E-03 1.01E-01 37 107 "ABR,ACTN1,ACTN2,PKP4,APC,CASK,ATP2B1,ATP2B2,DST,ARHGEF7,BTRC,TRIM41,DLGAP1,ZFYVE9,CLTC,PICK1,CTNND1,CTNND2,DBN1,DLG4,ERBB2,FOXO3,GRIN2C,GUCY1A2,ARHGAP19,KCNA4,LMO1,LMO2,SMAD1,MAP4,MPP2,MAPK12,PDZD2,ERBIN,NR2E1,VIPR2,XPO1" Interaction int:GRIK2 GRIK2 interactions 5.17E-05 7.52E-01 1.01E-02 1.02E-01 14 26 "CASK,CDH2,PICK1,CTNND1,DLG3,DLG4,GRIA1,GRIA2,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,TNIK" Interaction int:RIMS1 RIMS1 interactions 5.19E-05 7.54E-01 1.01E-02 1.02E-01 15 29 "BSN,CACNA1B,CAMK2A,RAB3C,RAB26,ERC2,AGAP2,RAPGEF4,RAB3A,RIMS1,SNAP25,TNIK,ERC1,STX1A,SYT1" Interaction int:RGS4 RGS4 interactions 5.36E-05 7.79E-01 1.01E-02 1.03E-01 10 15 "CALM1,KRIT1,COPB2,PREPL,EGFR,GABBR1,GNAO1,PTAFR,RGS4,PLCB1" Interaction int:NRCAM NRCAM interactions 5.36E-05 7.79E-01 1.01E-02 1.03E-01 10 15 "ANK2,DLG4,AGAP2,LNX1,FRMD5,NRCAM,PTPRB,MAGI3,NFASC,CNTN2" Interaction int:GAK GAK interactions 5.46E-05 7.93E-01 1.02E-02 1.03E-01 33 92 "KIDINS220,AP2A1,AP2A2,ALK,APP,NUMB,AP1M1,CALM1,HIP1R,CLTA,CLTB,CLTC,SEC24C,EDRF1,DBN1,SEC16A,FEM1B,TNK2,STAMBP,GOLGB1,KIF3A,CLASRP,SYNPO,MYO6,PIK3C2A,PPM1B,FBXW7,LGR4,SPTAN1,ATP13A2,ZNF106,HSPBP1,WNK1" Interaction int:CBY1 CBY1 interactions 6.12E-05 8.89E-01 1.13E-02 1.14E-01 48 152 "OSBPL6,LRFN1,LRCH2,DACT3,KSR1,CFAP410,MAP7,CDC25B,DCLK1,MAGI1,NUMBL,CLU,OSBPL3,SIPA1L1,HDAC4,CEP170,EGFR,KCTD3,DENND4A,TESK2,BAIAP2,FOXO3,USP21,ZNF638,ARHGAP19,DOCK7,KIF5C,KLC1,SRSF12,AFDN,NF1,TBC1D25,CDK18,PFKFB2,MAPKAP1,UHRF1BP1,PTPN13,RTKN,KIF1B,CAMSAP2,AGTPBP1,KIAA0930,CLASP1,CRTC1,TIAM1,TSC2,SPIRE1,GAN" Interaction int:WWC1 WWC1 interactions 6.48E-05 9.42E-01 1.18E-02 1.20E-01 25 63 "DYNLL1,MPDZ,BTRC,AIFM1,ARMC8,FEZ2,FEZ1,CSNK1E,KIAA0513,DCTN1,EPB41L2,DLC1,RAPGEF6,TUBGCP4,CIT,MOV10,PRKCZ,FAM219A,TNIK,DDN,EPB41L3,WWC1,FBXW11,AMOT,XPO1" Interaction int:PTPRB PTPRB interactions 7.17E-05 1.00E+00 1.28E-02 1.30E-01 11 18 "CNTNAP1,CNTN1,EGFR,GHR,NRCAM,PTN,PTPRB,PTPRG,MAGI3,TEK,GOPC" Interaction int:BIN1 BIN1 interactions 7.20E-05 1.00E+00 1.28E-02 1.30E-01 29 78 "AP2A1,AP2A2,AMPH,BIN1,MAP4K3,APP,SYNJ1,CALM1,CLTC,DNM1,DNM2,RBM12,SH3GLB1,TNK2,MAPT,MBNL1,MOV10,PDE4D,PTK2,RFX3,CLIP1,ATXN2,SH3GL2,SH3GL3,SHMT2,TNIK,SYNE2,SYN1,XRCC4" Interaction int:ACTN2 ACTN2 interactions 7.70E-05 1.00E+00 1.35E-02 1.37E-01 30 82 "ACTN1,ACTN2,ADORA2A,LRRC7,CAMK2A,CAMK2D,CAMK2G,NCOR1,DLG4,DISC1,MYOZ2,GRIN1,KCNA4,KCNN2,MYH3,MYH6,MYH7,LRP12,ATXN2,ATXN7,RTP5,PALLD,ERBIN,ITGB3BP,TPM1,TPM2,TPM3,TPM4,SYNPO2,ST7" Interaction int:SYNJ1 SYNJ1 interactions 8.06E-05 1.00E+00 1.39E-02 1.42E-01 16 33 "AP2A1,AMPH,BIN1,SYNJ1,CLTA,CLTC,DLG4,SH3GLB1,AGAP2,PACSIN2,PACSIN1,SH3KBP1,PPP3CA,ITSN1,SH3GL2,SH3GL3" Interaction int:CDH2 CDH2 interactions 8.15E-05 1.00E+00 1.39E-02 1.42E-01 31 86 "LRRC7,PKP4,NUMB,DDR1,CDH2,PPT2,PDE4DIP,CTNND1,CTNND2,BOC,ARHGAP32,DBN1,CDON,EGFR,ERBB2,FGFR1,GAA,GRIK2,GRIN1,GRIN2D,KIF5C,KTN1,CTNNA3,DDR2,PC,PIK3R1,PRPH,TNIK,SUPT5H,TPM4,FXR1" Interaction int:PTAFR PTAFR interactions 8.39E-05 1.00E+00 1.40E-02 1.42E-01 9 13 "ARRB1,ARRB2,CALM1,CLTC,GORAB,JAK2,PTAFR,PTK2,RGS4" Interaction int:HOXB1 HOXB1 interactions 8.39E-05 1.00E+00 1.40E-02 1.42E-01 9 13 "SERPINA3,RCHY1,NR3C1,HMGB1,MEIS1,PAX6,PBX1,PKNOX2,SIRT1" Interaction int:RAPGEF5 RAPGEF5 interactions 8.61E-05 1.00E+00 1.42E-02 1.45E-01 15 30 "ANK1,ANK2,ANK3,ATP2B2,FLNC,KCND3,PLEC,PRKACB,PRKAR1B,MRAS,CCDC88A,DDHD2,TUBB1,RICTOR,WNK1" Interaction int:FYN FYN interactions 8.88E-05 1.00E+00 1.43E-02 1.45E-01 71 252 "ADD2,CNTNAP1,ADAM15,BTK,WASF1,ARHGAP33,CLTC,CNN3,CNTN1,SLC4A8,CSF1R,SDC3,CTNND1,CTNND2,NOS1AP,ARHGAP32,DCC,YTHDC1,DLG4,TNK2,EFS,TUBA1B,PTK2B,RACK1,EVL,FLT1,FYB1,FYN,PRUNE2,GRB10,GRIN1,NR3C1,GRM1,PTPN5,HNRNPK,HSP90AA1,JAK2,KCNA2,KCNA4,KIT,MAG,MAP2,MAPT,NCAM1,NTRK2,PCDHGC3,PDE4D,GNG2,ANLN,PIK3R1,PMS2,SH3KBP1,PRKCZ,PTK2,PTPRD,PTPRE,PTPRZ1,SLC25A41,RPS6KA2,ATXN1,SH3BP2,MYO18A,SNCA,SON,ANKRD12,ZNF106,TNNT1,RBFOX2,VAV1,VAV2,SPHK2" Interaction int:TNR TNR interactions 8.92E-05 1.00E+00 1.43E-02 1.45E-01 14 27 "CCDC146,CNTN1,VCAN,NCAN,PDE4DIP,AGAP2,PTPRZ1,CNKSR2,BCAN,TNIK,NFASC,TNR,TSC1,FXR1" Interaction int:AP2M1 AP2M1 interactions 8.94E-05 1.00E+00 1.43E-02 1.45E-01 65 226 "RALGAPA1,ADRA1B,AP2A1,AP2A2,AP1B1,AMPH,APC,AQP4,ARRB2,NUMB,SYNJ1,CACNA1A,DGKI,CDK11B,REPS2,EPS15L1,CLTB,CLTC,CRY2,NCOR2,CTNND1,PPP6R2,NOS1AP,TBC1D5,DBN1,SV2A,SNX29,EGFR,TUBA1B,TUBB3,MEGF10,GFAP,RUNDC3A,LNX1,TUBA1C,ATXN2L,SYNPO,HSPA1L,KCNJ11,L1CAM,MAP4,MYO6,OCRL,ANLN,EPN1,PRKACB,PRKAR1B,MASP1,PEX5,ATG16L1,SLC25A41,RPL38,SFPQ,ITSN1,MYO18A,ARFGAP1,KIF13A,STAU1,ANKRD28,PJA1,FAM208A,TUBB2A,UBC,XPO1,TUBA1A" Interaction int:ARHGAP32 ARHGAP32 interactions 9.28E-05 1.00E+00 1.47E-02 1.49E-01 23 57 "ARRB1,CAMK2A,CDC42,CDH2,DLGAP1,PDE4DIP,DZIP3,ARHGAP32,DLG4,EGFR,ABI2,ASB3,SYNCRIP,FYN,MEGF10,GAB1,CAMK2N2,MDFI,SHC3,PIK3R1,ATXN1,TNIK,TSC1" Interaction int:NCK2 NCK2 interactions 9.46E-05 1.00E+00 1.48E-02 1.50E-01 44 138 "SEMA6A,CPNE5,ARHGEF7,WASF1,DDR1,TRIM41,CHN1,MAP4K4,ARHGEF6,ARHGAP32,GIT2,CEP170,DNM1,ABI1,ATN1,EGFR,ABI2,TNK2,ERBB2,FGFR1,BAIAP2,SORBS1,FYB1,NCKAP1,WASF3,LNX1,SYNPO,HNRNPK,LIMS1,PIK3AP1,AFDN,GIT1,NTRK2,PKN2,MASP1,PTK2,TNIK,RBM26,SRPK2,TCF4,TNR,WIPF1,WIPF2,NHSL1" Interaction int:DNM2 DNM2 interactions 9.68E-05 1.00E+00 1.50E-02 1.52E-01 42 130 "AP2A1,AMPH,BIN1,APP,DYNLL1,DCTN1,TIAM2,DNM1,DYNC1I1,DNM2,SHANK1,ABI1,SH3GLB1,EGFR,FER,MPP6,GDF9,CNTRL,PACSIN2,MAN1B1,HMGB1,KCNN3,PDGFRA,PIK3R1,PACSIN1,SH3KBP1,PTK2,PTPN13,RPE,SCN2B,ITSN1,SH3GL2,SHANK2,ATF7IP,FNBP1,STAU1,UBC,VAV1,TBC1D15,LYPD6,ZBTB16,DNALI1" Interaction int:TIAM1 TIAM1 interactions 9.96E-05 1.00E+00 1.52E-02 1.55E-01 30 83 "LRFN1,ANK1,ANK3,KSR1,BTRC,CAMK2G,CDC25B,DCLK1,MAGI1,CSNK1E,SIPA1L1,HDAC4,KCTD3,EPHB1,TESK2,USP21,ZNF638,GRIN1,SRSF12,NF1,MAPKAP1,PRKCB,PRKCG,PRKCZ,RTKN,CAMSAP2,FBXW11,TIAM1,PARD3,NSD2" Interaction int:SNAP25 SNAP25 interactions 1.18E-04 1.00E+00 1.79E-02 1.82E-01 25 65 "AP2A1,APP,ATP1A1,FBXO7,DNM1,STX2,SYT3,NCKAP1,CPLX1,KCNB1,KIF5C,MAP6,SYT9,PRRT2,ITSN1,RIMS1,SNAP25,SNCA,STX1A,STXBP1,SYP,SYT1,TUBB2A,TRIM9,TUBA1A" Interaction int:GRID2 GRID2 interactions 1.19E-04 1.00E+00 1.79E-02 1.82E-01 10 16 "AP4M1,MAGI2,DLG2,EML1,GRIA1,GRIA2,GRIK2,GRIK5,SHANK2,GOPC" Interaction int:PRKCA PRKCA interactions 1.24E-04 1.00E+00 1.84E-02 1.87E-01 77 281 "ADCY5,ADD3,ADRA1B,ANXA7,APC,DGKZ,DGKD,NUMB,ATM,ATP1A1,ATP2B1,ATP2B2,BTK,TRIM41,ARHGEF1,CDC42,FBXO7,PICK1,AKAP5,CREM,AKAP12,FBXO25,DLG4,DNM1,EEF1D,EGFR,RACK1,AGAP2,FLNC,GABRB3,GABRG2,GFAP,GJB1,LNX1,GPM6A,ADAP1,GRIA1,GRIA2,GRIA4,GRIN1,GRM1,GRM5,GRM7,HMGB1,HSP90AA1,ITPKA,ITPKB,KCNQ2,KIF2A,KIT,MBP,MOV10,NFE2L2,NOS1,NRGN,OGG1,PFKFB2,MAPKAP1,PPARA,PRKCB,PRKCG,PRKCZ,MAPK7,SLC25A41,RGS7,FBXW7,SELL,SLC6A9,SNAP25,SPP1,STXBP1,FGD4,PLCB1,WWC1,TIAM1,TRPC3,RICTOR" Interaction int:LRRC7 LRRC7 interactions 1.53E-04 1.00E+00 2.24E-02 2.27E-01 12 22 "ACTN2,LRRC7,ADGRB1,CAMK2A,CAMK2G,CDH2,DLGAP1,CTNND2,DLG4,AGAP2,CNKSR2,TNIK" Interaction int:SHANK1 SHANK1 interactions 1.54E-04 1.00E+00 2.24E-02 2.27E-01 13 25 "ADGRB2,ARHGEF7,DLGAP1,PDE4DIP,DLG4,DNM2,SHANK1,BAIAP2,AGAP2,RPS6KA2,TNIK,SPTAN1,SSTR2" Interaction int:BAIAP2 BAIAP2 interactions 1.57E-04 1.00E+00 2.25E-02 2.29E-01 29 81 "HECW2,APP,ADGRB1,KSR1,WASF1,CDC42,DLGAP1,CSNK1E,DLG4,SHANK1,ABI1,ATN1,EGFR,KCTD3,EPS8,BAIAP2,NCKAP1,GRB10,PTPRE,RAP1GDS1,CNKSR2,SHANK2,TNIK,RBM26,SRPK2,KANK1,TP53BP2,RTN4,FXR1" Interaction int:AP2A2 AP2A2 interactions 1.63E-04 1.00E+00 2.32E-02 2.35E-01 30 85 "AP2A1,AP2A2,AP1B1,AMPH,BIN1,APP,ARRB2,NUMB,ATP1A1,CLTB,CLTC,DBN1,DNAJC6,SNAP91,DNM1,EGFR,AGAP2,RUNDC3A,SMAD1,MOV10,MYO6,OCRL,NLGN3,EPN1,ARFGAP1,TNIK,FCHO1,TMPO,UBC,FXR1" Interaction int:PLCG1 PLCG1 interactions 1.64E-04 1.00E+00 2.32E-02 2.35E-01 50 166 "ALK,DGKZ,TTC9B,BTK,LDLRAD4,DDR1,CAMK2A,ARHGEF2,ARHGAP32,SNAP91,DNM1,EGFR,ERBB2,RACK1,FGFR1,AGAP2,SYNCRIP,FLT1,FYN,GAB1,GHR,GRIN1,GSN,HNRNPK,JAK1,JAK2,KCNJ5,KIT,LIFR,GIT1,NCAM1,NTRK2,NTRK3,PDGFRA,PFKP,PLXNB1,PKN2,PTK2,KHDRBS2,RET,UBR7,MCMBP,RPL38,SH3BP2,SYN1,TRPC3,TUB,VAV1,LAT2,MVB12B" Interaction int:LIN7A LIN7A interactions 1.70E-04 1.00E+00 2.38E-02 2.42E-01 17 38 "PPFIA2,APP,CASK,ADGRB1,MPDZ,DLG2,DLG3,DLG4,EPB41L2,BAIAP2,MPP6,GUCY1A2,GUCY1B1,KCNJ4,MPP2,CADM1,AMOT" Interaction int:DRD2 DRD2 interactions 1.93E-04 1.00E+00 2.68E-02 2.72E-01 16 35 "ADORA2A,ARRB2,CADPS,CALM1,DLG4,DNM1,EGFR,EPB41,EPB41L1,GRIA2,KCNJ3,KCNJ5,KCNJ9,MSRA,SH3KBP1,SH3GL2" Interaction int:GTSE1 GTSE1 interactions 2.01E-04 1.00E+00 2.76E-02 2.80E-01 43 138 "KIDINS220,AP2A1,AP2A2,AP1B1,PKP4,NUMB,BARD1,SYNJ1,AP1M1,HIP1R,CDC42,NUMBL,CLTA,CLTB,CLTC,SEC24C,CSNK1E,DBN1,DCTN1,KIAA0753,CEP170,SEC16A,TNK2,SEC24B,VTI1B,STAMBP,WASHC2A,TNRC6A,CNTRL,MYO6,OCRL,PIK3C2A,ANLN,EPN1,SH3KBP1,ARX,BTBD3,EPN2,ERBIN,DNMBP,ZNF106,XPO1,WNK1" Interaction int:RAP1A RAP1A interactions 2.17E-04 1.00E+00 2.94E-02 2.99E-01 32 94 "BIN1,ARHGDIA,KRIT1,ARHGEF1,DGKI,CDK11B,CDC42,DLGAP1,TBRG4,DUSP9,RASGRP2,FGFR1,RAPGEF6,CPLX2,RUNDC3A,RAPGEF4,RAPGEF1,GRIN1,GABARAPL2,KCNMA1,AFDN,HNRNPM,RAB5B,RALGDS,RAP1GAP,RAP1GDS1,RASA3,RADIL,SMARCA4,GANAB,SIRT1,TSC2" Interaction int:ARRB1 ARRB1 interactions 2.20E-04 1.00E+00 2.94E-02 2.99E-01 71 259 "RBM10,ADRB2,AP2A1,APLP1,DGKZ,ARRB1,ARRB2,PTCH2,ALDH4A1,DCAF5,BTK,INA,CDC42,CLTA,CLTC,CNGA3,SDC3,DOCK4,ARHGAP32,KIF26A,DGKG,DMD,DNM1,ARRDC4,EDNRA,EEF1A2,EGFR,KCTD3,PRMT5,FGR,NEK6,SPIN1,TUBA1C,GSN,KIF3A,BACH2,HNRNPK,HSP90AA1,JAK1,KHK,STXBP5,KTN1,LRP1B,HNRNPM,PDE4D,GNG2,PFKFB3,PIK3C2A,PKM,PPM1B,MAPK3,MAPK9,MAPK10,PTAFR,PTHLH,PTH1R,RALGDS,RGS3,RPL15,SLC9A5,ELMO2,SNCA,USP33,SPTAN1,ZBTB43,MPRIP,TMPO,TPM4,TUBB2A,RPL7L1,HNRNPA3" Interaction int:PRNP PRNP interactions 2.21E-04 1.00E+00 2.94E-02 2.99E-01 37 114 "SPARCL1,APBB1,APLP1,APP,ZFYVE28,MARK4,ATP1A1,ATP1A3,ATP2B2,CADM3,ADAM23,CLU,CNTN1,TBPL1,PDE4DIP,NTM,DNM1,DPP6,DPYSL2,FGF13,FHL1,ZBED3,AIFM3,HSP90AA1,L1CAM,LSAMP,MAG,MBP,MOG,NCAM1,NCAM2,OPCML,PLP1,CLSTN1,STXBP1,SYN1,TMEM237" Interaction int:PPFIA4 PPFIA4 interactions 2.31E-04 1.00E+00 2.95E-02 3.00E-01 6 7 "PPFIA4,CAST,ERC2,DISC1,GIT1,AGTPBP1" Interaction int:GRIK3 GRIK3 interactions 2.31E-04 1.00E+00 2.95E-02 3.00E-01 6 7 "GRIK2,GRIK3,GRIK4,GRIK5,FBXW7,FXR1" Interaction int:KCNIP1 KCNIP1 interactions 2.31E-04 1.00E+00 2.95E-02 3.00E-01 6 7 "KCND1,KCND2,KCND3,KCNIP2,KCNIP1,SPP1" Interaction int:DDN DDN interactions 2.31E-04 1.00E+00 2.95E-02 3.00E-01 6 7 "ACTN1,MAGI1,DLGAP1,SH3KBP1,DDN,WWC1" Interaction int:SORBS2 SORBS2 interactions 2.31E-04 1.00E+00 2.95E-02 3.00E-01 23 60 "ACTN1,SEMA6A,ADAM15,SYNJ1,WASF1,DLGAP2,DLGAP1,CLTC,PDE4DIP,DBN1,DLG4,EGFR,EFS,PTK2B,AGAP2,SYNPO,AFDN,ANLN,PKM,MYO18A,PALLD,TNIK,MYCBP2" Interaction int:PDE4D PDE4D interactions 2.59E-04 1.00E+00 3.25E-02 3.30E-01 19 46 "BIN1,APP,ARRB1,ARRB2,FBXO7,AKAP6,AKAP12,PDE4DIP,RACK1,FYN,ITPKB,PDE4B,PDE4D,PFKFB2,PIK3R1,PPP3CA,PPP3CB,ITSN1,SPTAN1" Interaction int:CAMK4 CAMK4 interactions 2.63E-04 1.00E+00 3.25E-02 3.30E-01 11 20 "ARHGEF7,PPP6R2,HDAC4,GIT2,CAMKK2,HSP90AA1,RBPJ,GIT1,NOS1,ANKRD28,CABIN1" Interaction int:GABRA3 GABRA3 interactions 2.66E-04 1.00E+00 3.25E-02 3.30E-01 12 23 "SEC11C,TMEM59L,EGFR,POMT1,SDCBP2,GABRA1,GABRA3,GABRA5,GLRB,ALG9,WLS,TTC17" Interaction int:NLGN2 NLGN2 interactions 2.66E-04 1.00E+00 3.25E-02 3.30E-01 12 23 "NRXN3,NRXN1,NRXN2,CLU,B3GAT3,DLG2,DLG3,DLG4,GABRA1,NLGN3,SUSD4,TNIK" Interaction int:SNTA1 SNTA1 interactions 2.66E-04 1.00E+00 3.25E-02 3.30E-01 31 91 "ADRA1D,DGKZ,ATP2B2,ADGRB1,ADGRB2,ADGRB3,RGS11,MTMR2,CALM1,GDA,DMD,DTNA,DTNB,GLS,PRLHR,GUCY1A2,ADAMTS6,KCNA4,KCNJ4,KCNJ10,LMO1,MAP4,NOS1,MAPK12,CNKSR2,SLC1A7,MAST1,KIF1B,SSTR1,MLC1,TNS2" Interaction int:LGI1 LGI1 interactions 2.73E-04 1.00E+00 3.25E-02 3.30E-01 5 5 "LGI1,DLGAP1,DLG4,ADAM22,TSC1" Interaction int:BHLHB9 BHLHB9 interactions 2.73E-04 1.00E+00 3.25E-02 3.30E-01 5 5 "APP,IPO5,PTPA,PPP2R5E,BHLHB9" Interaction int:CAMK2N2 CAMK2N2 interactions 2.73E-04 1.00E+00 3.25E-02 3.30E-01 5 5 "CAMK2A,CAMK2B,ARHGAP32,LNX1,CAMK2N2" Interaction int:CASK CASK interactions 3.32E-04 1.00E+00 3.89E-02 3.95E-01 31 92 "CASKIN1,PPFIA2,CASK,CACNA1B,DLGAP1,NRXN3,NRXN1,NRXN2,WHRN,CNTNAP2,SDC3,SPATA2,DLG4,DTNB,EPB41,EPS8,TBR1,GRIK2,KCNA4,KCNJ4,P2RX7,PPM1B,RAB3A,FOXRED2,RPH3A,PPP4R3A,TNIK,TSPYL2,SRPK2,ERBIN,CADM1" Interaction int:PTK2B PTK2B interactions 3.34E-04 1.00E+00 3.89E-02 3.95E-01 32 96 "PITPNM2,ARHGAP5,DLGAP3,PITPNM3,DLG3,DLG4,DNM1,PDCD6IP,EGFR,ERBB2,EFS,PTK2B,FGFR3,AGAP2,FLT1,FYN,GP1BB,GRIN1,GSN,HSP90AA1,JAK1,JAK2,KCNA2,MAPT,MATK,GIT1,PDPK1,PIK3R1,SH3KBP1,PTK2,SNCA,VAV1" Interaction int:SIPA1L1 SIPA1L1 interactions 3.35E-04 1.00E+00 3.89E-02 3.95E-01 33 100 "OSBPL6,LRFN1,KSR1,KALRN,CDC25B,DCLK1,MAGI1,NRXN1,SIPA1L1,HDAC4,DLG4,DYRK1A,KCTD3,DENND4A,TESK2,WDR83,USP21,ZNF638,NUDT21,SYNPO,SRSF12,AFDN,NF1,TBC1D25,ODF2,MAPKAP1,PTPN13,RTKN,TNIK,CAMSAP2,FBXW11,RPGRIP1L,TIAM1" Interaction int:CLTC CLTC interactions 3.37E-04 1.00E+00 3.89E-02 3.95E-01 82 312 "ADRB2,KIDINS220,AP2A1,AP2A2,AP1B1,MTUS1,AMPH,BIN1,PKP4,ARRB1,ARRB2,NUMB,ATP1A1,ATP1A2,ATP1A3,ATP6V0A1,SYNJ1,CANX,HIP1R,ZFYVE9,CLTA,CLTB,CLTC,FBXO7,CSF1R,SEC24C,CSNK1E,IST1,DBN1,DNAJC6,DCTN1,SNAP91,SEC16A,DLG4,DNM1,TOM1,DYRK1A,TNK2,ERBB2,NCALD,SEC24B,VTI1B,AGAP2,STAMBP,FYN,TNRC6A,CNTRL,GRIN1,GRIN2D,SYNPO,KIT,IPO5,POC1B,MYO6,OCRL,PIK3C2A,ANLN,EPN1,SH3KBP1,PTAFR,PTCH1,RAB5B,CEP97,ATG16L1,LRRK2,LGR4,ITSN1,ARX,MYO18A,BTBD3,EPN2,SNCA,SPART,ERBIN,STAU1,FBXW11,OBSL1,TMPO,TOM1L2,RICTOR,WNK1,AP3B2" Interaction int:MAPK8IP1 MAPK8IP1 interactions 3.61E-04 1.00E+00 4.13E-02 4.20E-01 17 40 "ANK2,ANK3,APP,FEM1B,EGFR,ERBB2,TUBB3,KLC1,HCN1,MAPK8,MAPK9,MAPK10,SNCA,MAPK8IP3,TIAM1,MAP3K12,LRP8" Interaction int:TSC1 TSC1 interactions 3.75E-04 1.00E+00 4.26E-02 4.33E-01 49 167 "AMPD2,WASF1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,ARHGEF2,LGI1,MAGED1,CNRIP1,NCAN,APPL1,ARHGAP32,TCAF1,MATR3,DAPK1,DLG4,ABI1,DYRK1A,RACK1,FOXG1,SMC2,FAM49B,NCKAP1,HSP90AA1,DOCK7,KIF5C,MOV10,PPP3CA,PRKCB,PRKCG,PTK2,RDX,ATXN1,SFPQ,TNIK,DOK5,CLASP1,TNS2,AKTIP,TNR,TP53BP1,TSC1,TSC2,TTC3,WNK3,WNK2,PAK5,FXR1" Interaction int:PTK2 PTK2 interactions 4.07E-04 1.00E+00 4.49E-02 4.56E-01 47 159 "ACTN1,AMPH,BIN1,APC,APP,RIPK1,DLGAP1,DLGAP3,DCC,DLG4,DNM2,PDCD6IP,EGFR,ERBB2,EFS,PTK2B,FGR,AGAP2,FLT1,SORBS1,FYN,GSN,HSP90AA1,ITGAV,JAK2,KCNMA1,GIT1,NASP,GNG2,PIK3R1,PKD1,SH3KBP1,PTAFR,PTK2,PTPRH,RET,ZNF331,ARHGAP26,NACAD,MAPK8IP3,TEK,TNS1,TRIO,TSC1,TSC2,UBE2H,MICAL1" Interaction int:CACNA1A CACNA1A interactions 4.08E-04 1.00E+00 4.49E-02 4.56E-01 34 105 "ACTN1,HHATL,C1QTNF1,LTBP4,CACNA1A,CACNB2,CACNB4,KALRN,ARHGAP22,DNAJB5,CABP1,SUMF2,CRMP1,IP6K1,OLIG1,ABI1,EFEMP1,NELFCD,ZCCHC17,KHDRBS3,SRRM4,TUBB2B,MATK,MATN2,NELL1,NELL2,PCSK5,REV3L,SCP2,PUF60,TNIK,HECW1,SYT1,RIMBP2" Interaction int:EML1 EML1 interactions 4.11E-04 1.00E+00 4.49E-02 4.56E-01 9 15 "DCTN1,EML1,TUBA1B,TUBB3,EML4,GRID1,TUBB2B,TUBB2A,TUBA1A" Interaction int:SSTR3 SSTR3 interactions 4.11E-04 1.00E+00 4.49E-02 4.56E-01 9 15 "MPDZ,MAGI1,TJP2,MPP6,LNX1,MAGI3,SST,TJP1,GOPC" Interaction int:GRIA4 GRIA4 interactions 4.11E-04 1.00E+00 4.49E-02 4.56E-01 9 15 "ACTN1,CAMK2G,PICK1,DLG4,EPB41L1,CACNG2,GRIA1,GRIA4,PRKCG" Interaction int:L1CAM L1CAM interactions 4.22E-04 1.00E+00 4.55E-02 4.62E-01 16 37 "AP2A1,ANK1,ANK2,NUMB,CANX,CNTN1,NCAN,EGFR,ERBB2,FGFR1,ITGAV,L1CAM,NCAM1,RDX,RPS6KA2,CNTN2" Interaction int:GRIN2D GRIN2D interactions 4.22E-04 1.00E+00 4.55E-02 4.62E-01 16 37 "INA,CDH2,DLGAP1,CLTC,DLG2,DLG4,DNM1,GRIN1,GRIN2D,CIT,MAP2,NF1,PRKCB,PRKCG,SPTAN1,TJP1" Interaction int:GHDC GHDC interactions 4.43E-04 1.00E+00 4.72E-02 4.79E-01 12 24 "PCDHGB4,ATP2B2,SEC11C,FAM189A2,CNGA3,SLC4A8,TSPAN5,GHDC,TMEM206,PCDHAC2,PCDHA3,LRP8" Interaction int:PIK3R1 PIK3R1 interactions 4.48E-04 1.00E+00 4.72E-02 4.79E-01 67 247 "SNX32,ALK,ANK3,PROM1,WASF1,CDC42,CDH2,SOCS6,NCOR1,CSF1R,CSF2RA,APPL1,ARHGAP32,DNM1,NYAP1,DNM2,ABI1,EGFR,EPS8,ERBB2,TUBA1B,PTK2B,FER,FGFR1,AGAP2,FLT1,FYN,GAB1,NCKAP1,WASF3,GHR,GRB10,GRIN1,VSIG4,HNRNPK,IL6ST,JAK1,JAK2,KIT,PIK3AP1,MAPT,NTRK2,PDE4D,PDGFRA,NLGN3,PIK3CD,PIK3R1,EPN1,SH3KBP1,MAPK8,PTK2,PXK,RET,RXRA,ITSN1,MYO16,ENKUR,SPP1,SSTR2,SYN1,TEK,SIRT1,TIE1,RASD2,TUB,FLRT1,VAV1" Interaction int:SH3GL2 SH3GL2 interactions 4.52E-04 1.00E+00 4.72E-02 4.79E-01 25 70 "AMPH,BIN1,MAP4K3,APP,TMEM108,ADAM15,SYNJ1,CALM1,TIAM2,ARNT2,DNM1,DNM2,PDCD6IP,DYRK1A,EGFR,DPYSL4,SH3KBP1,LRRK2,ATXN2,ITSN1,SH3GL2,SH3GL3,TNIK,SYN1,SLC17A7" Interaction int:KLHDC3 KLHDC3 interactions 4.54E-04 1.00E+00 4.72E-02 4.79E-01 21 55 "BRAP,FOXK1,CSNK1E,DAPK3,FBXL5,G3BP2,DLG3,DPYSL2,DPYSL4,DIDO1,VSIG4,AFDN,MOV10,CRTAC1,RPL15,CLASP2,TBL1X,UBC,EIF4ENIF1,XPO1,DPYSL5" Interaction int:INA INA interactions 4.54E-04 1.00E+00 4.72E-02 4.79E-01 21 55 "ARRB1,KALRN,INA,DLG4,AGAP2,GFAP,GRIN1,GRIN2D,KCNMA1,NEFM,NEFH,ODF2,CNKSR2,TNIK,STAU1,OBSL1,PRMT8,SYNC,RSPRY1,FXR1,GAN" Interaction int:SHC3 SHC3 interactions 4.61E-04 1.00E+00 4.75E-02 4.83E-01 11 21 "ALK,APP,ARHGAP32,EGFR,ERBB2,GRIN1,SHC3,NTRK2,RET,SH3GL3,SHC4" Cytoband 5q31 5q31 7.04E-14 8.27E-11 8.27E-11 6.33E-10 42 115 "NME5,PCDHGB4,ALDH7A1,KLHL3,CDKL3,REEP2,FGF1,BRD8,TCERG1,KIF3A,PCDHGC3,PCDHB17P,ARHGAP26,SEPT8,ACSL6,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Transcription Factor Binding Site CAGGTG_V$E12_Q6 CAGGTG_V$E12_Q6 4.56E-19 2.80E-16 2.80E-16 1.96E-15 558 1956 "TTYH1,ABR,ASIC2,ASIC1,ACLY,EMILIN3,ACTN2,ARID1A,DSCAML1,ADCY8,ADD3,AXIN2,SLC12A5,ADRA1B,ADRB2,AP1B1,MTUS1,GPR158,KLHL13,CASKIN1,KIAA1324,PLA2G6,C1QTNF1,SEMA6A,C1QTNF4,ALCAM,MRTFA,DOC2A,AMPD2,ANK1,ANK2,ANK3,MAP4K3,PKP4,KCNAB2,EPB41L5,DGKZ,DGKD,USP37,APP,SEMA4G,MADD,ARHGAP5,ARRB2,DDX3Y,ATM,ATP2B3,NOL4,ADGRB2,NRP2,BMP7,BMPR1B,JAZF1,CACNA1G,CACNA1D,CACNA1E,DDR1,CACNB2,CALB1,CALM1,KALRN,NGB,CAMK2A,CAMK2B,CAMK2G,TRIM41,CANX,SLC25A14,SYT6,CAST,RHBDL1,SPAG9,MAP7,CBLN1,SHISA7,KYAT1,CCKBR,USP2,SYNGR3,ENTPD2,NEURL1,DGKI,AP4M1,CDH2,MAGI1,TIGD7,CRLF1,UBE2L6,NUMBL,CACNA2D2,CHRM1,PLEKHB1,CASC2,B4GALT6,SLIT2,RAB33A,NRXN3,ZFYVE9,PPT2,NRXN1,SLC24A2,NMT2,DNAJB5,RAB26,CCDC151,COL9A3,COL11A2,SLC4A8,TBPL1,ZNF521,NRG2,AKAP12,CRMP1,NCOR1,SNCAIP,RGS6,LRIG1,MICAL2,SOCS5,RIMS4,PHACTR3,PPP1R16B,CALY,UBXN2A,GREB1,CTNND1,RIMS2,HDAC9,ARHGAP32,ARHGAP24,RASSF2,PHYHIP,DGKG,DAPK1,SPOCK2,GIT2,ARMCX2,DCT,DCTN1,ELMO1,C2CD2L,KLHL3,RHOBTB1,SV2B,SV2A,AK5,G3BP2,WDR20,DLG2,DMD,HS3ST4,DMPK,NYAP1,CALN1,CDON,SHANK1,SLC12A6,DRP2,DSCAM,DTNB,DUSP9,WDPCP,EDN1,PHC2,CNNM1,HEYL,PLXNC1,ELAVL3,ELAVL4,RGS17,BSCL2,ELN,EML1,EPB41,DMTN,RASGRP2,EPS8,ERBB4,ETV1,RTN3,RASL12,EYA1,ARMCX1,CLVS1,ACSL4,PTK2B,ZIC4,CORO2B,EFEMP1,FGF1,FGF11,FGF12,FGF13,FGR,PRKAG2,POLK,HPCAL4,IP6K2,AGAP2,SYNCRIP,AGAP3,SEMA6C,FLNC,SYT3,NBEA,TACC2,SORBS1,NSG2,CELF1,FUT9,TBR1,FYN,GABRA3,CHL1,GABRB1,GABRG2,GAD1,GAD2,AHCYL1,NKX6-2,ARPP21,GALR1,IP6K3,IQGAP2,GAP43,GATM,GCK,GFAP,GFRA1,PCDH17,PPARGC1A,KIRREL3,GJB1,RUNDC3A,NTNG2,GK,GLI2,HTATSF1,GNAO1,GNAS,GNG3,GPD1,GPM6B,TDRKH,EML4,GPR37,RAPGEF4,STMN2,GRIA1,PLCD4,GRIK3,GRIK5,GRIN1,ADAMTS8,NR3C1,GRM1,GRM8,ZNF496,LINC01089,CLASRP,IL1RAPL1,KAT7,AP4S1,PSIP1,GUCY1A1,GUCY1B1,CELF3,HRH3,ZDHHC15,NEGR1,MYLK2,RBPJ,USP54,IGSF1,IL6R,SCRT2,IL11RA,ZNF385B,ITGA7,ITPKA,KCNA4,KCNB1,KCNC2,KCND1,KCND2,KCND3,KCNH2,KCNJ4,KCNJ9,KCNJ11,KCNK1,KCNMA1,KCNN2,KCNN3,KCNQ3,KIT,KTN1,LMO1,LMO2,HECTD2,PIK3AP1,MAPT,MARK1,MATK,CHST6,ADAM11,MEF2C,MEIS2,SCAMP5,MID1,MMP16,GIT1,SESN3,STK32C,MT3,MDGA1,HS6ST3,MYH6,MYL3,NACA,NBL1,NCAM1,NCAM2,NDP,RCOR2,NEFH,NEUROD1,NFIX,NHLH1,NNAT,NODAL,NOS1,CNOT4,NOVA2,NPPA,NPTX1,NPTX2,NRCAM,NTRK2,NTRK3,OMG,OPHN1,ZNF827,KCNK10,PAK3,PALM,PAX6,PC,CDK18,PDE1C,PDE2A,PDE3A,PDE4B,PDGFRA,ENPP2,PDYN,PFKFB2,CDK14,SERPINE2,SERPINI1,PIK3CD,PIK3R1,SNX10,KCTD15,PLCB2,PLEC,FXYD1,SLC25A23,HMGCLL1,PMP22,STRN3,MAGEL2,ING3,EPB41L4B,FA2H,NXPH1,POU3F2,POU3F4,PPARA,PPP2R2B,PTPA,RASGEF1B,CEP41,PKIA,PRKCG,PRKCZ,MAPK10,PROX1,PRPH,MASP1,CNNM2,PSD,GDPD2,ANKHD1,PTHLH,STK32A,PTPRB,EML5,PTPRO,TTC13,STRC,RAB5B,OXR1,RASGRF2,KHDRBS2,TSPY26P,REV3L,RFX3,RGS3,RGS7,RIT2,PBRM1,LGI2,ZNF532,MYH14,ROM1,RORB,KCNIP2,KCNIP1,RTN1,RYR1,RYR3,TRAPPC13,MAPK12,LRFN5,SCN2B,HES6,SMPD3,ASIC4,TRIM46,SELL,ZNF821,SH3GL2,CPEB3,MYO18A,SLITRK3,CNKSR2,ABLIM3,RPH3A,SLC1A7,BTBD3,SMTN,SLC6A7,SLC6A11,SHANK2,SMARCC2,TTC17,SNAP25,SNCA,KIF13A,SCN3B,WDTC1,TRERF1,SOX3,SOX10,SOX15,UNC5B,ARHGAP26,SPTAN1,SPTB,RAP1GAP2,LMO3,TAB2,CAMTA2,SMOC1,SSTR1,NKAIN2,NCDN,STX1A,SEPT3,STXBP1,GSE1,SYT11,FGD4,SYNE2,VPS13A,ADAMTS17,PLCB1,SYT1,COBL,SYT4,TAC1,TACC1,TACR1,ROBO3,TAL1,PDLIM2,CNTN2,FBXW11,TCEA1,TCF7,SYNE1,RALYL,ARHGEF12,PCDHA6,PCDHA1,HIF3A,SIRT1,CHST8,HHIP,FBXL16,THRA,TIAM1,TJP1,TLL2,ZFP91,NR2E1,TMOD1,DAAM2,TP53BP1,RASD2,TPM3,WBP2,TRPS1,SSBP2,HSPBP1,CLHC1,TMEFF2,HIRA,AMOT,UBTF,FLRT1,FAM181B,USP1,MGAT5B,VGF,KCNK12,ZIC2,ZIC3,NDRG4,SLC26A10,CELF4,ZNF189,DPYSL5,SH3GLB2,SLC30A3,CA10,PMEPA1,RGMA,STMN4,PRDM10,LMAN2L,SCG2,SEMA3B,PCDH15,GAL3ST3,NAV2,FIP1L1,PCBP4,SLC17A6,RTN4,PAK5,GJC2,JMJD1C,NETO2,DPF3,SLC4A10,JPH3" Transcription Factor Binding Site CTGCAGY_UNKNOWN CTGCAGY_UNKNOWN 7.84E-18 4.81E-15 2.41E-15 1.68E-14 216 607 "SLITRK1,ADD3,AXIN2,SLC12A5,ADORA2A,AP2A1,MTUS1,KLHL13,C1QTNF3,SEMA6A,ALCAM,ABCD2,DOC2A,ANK3,PHF12,APBB2,APP,CASK,ATP1A3,STX16,B3GALT2,NOL4,ADGRB2,ADGRB3,CDK5R2,CACNB2,CALM1,CAMK2D,CAMK2G,SPAG9,CBLN1,SHISA7,SLC5A11,CDH2,DCLK1,DLGAP1,CFL2,FOXN3,CHGA,RAB3C,NRXN3,NRXN1,COL11A2,MAGED1,IFFO1,TBPL1,BAG4,ABCG1,PHACTR3,SLITRK5,CTNND1,CTNND2,HDAC9,SNPH,SPOCK2,GIT2,ELMO1,DLG2,DLG3,GRIN3A,DMD,DNM1,CD99L2,CALN1,DMTF1,DPYSL2,DSCAM,DUSP9,CNNM1,GPR61,MBNL2,EGR3,EIF4G2,ELAVL4,BSCL2,DCTN4,ENO2,EPB41,DMTN,GPHN,APC2,ETV1,RRAGB,CACNG3,CACNG2,DLC1,FGF1,FGF11,FGF12,FGF13,FGF14,FGFR1,FHL1,MEX3B,IP6K2,FOXO3,SYT3,NBEA,TACC2,USP21,ATP2C1,CELF1,TPPP3,FYN,GABRA3,KIAA1841,PCDH17,GGT7,RAB30,PCSK1N,GNG3,GPM6A,STMN2,GRIA4,GRIK2,GRIN2D,IL1RAPL1,HRH3,KLF12,HPSE2,MYLK2,NKD1,IGSF1,LRRTM1,ITGA7,KCND1,KCNH2,KCNN2,KCNN3,MAP4,MAPT,ADAM11,LRP1B,MEIS1,KITLG,AMZ2P1,NAP1L2,NBL1,RCOR2,NFIX,NNAT,NOVA1,NTRK2,OMG,OPCML,PAX6,PCDH9,PDE4D,NLGN3,SEMA5B,PIK3R1,PLXNB1,PNMA3,EPB41L4B,PPP2R2B,PPP2R5C,MAPK7,PSD,SYTL2,PTK2,PTX3,RAB3A,RAB5B,RAD51D,PRIMA1,ZNF532,FBXW7,RTKN,KCNIP1,SALL1,SARS,SATB1,LRFN5,SCN8A,MYO18A,SLITRK3,ATF7IP,SMARCD3,RIMS1,SNRPN,SOX2,SOX10,ZSWIM8,BEX1,LMO3,C11orf87,POGZ,EPB41L3,NCDN,TTBK2,RGL1,GANAB,ANKRD28,CNTN2,SZT2,PCDHB15,PCDHB4,NSD1,PUM2,CHST8,HEY1,TIMP4,RBFOX2,TRPS1,FNDC5,RUSC1,HIRA,VSNL1,XPO1,SLC26A10,FSTL5,GAL3ST3,KCNAB1,RTN4,JMJD1C,SLC4A10" Transcription Factor Binding Site CTTTGT_V$LEF1_Q2 CTTTGT_V$LEF1_Q2 1.39E-17 8.51E-15 2.84E-15 1.98E-14 454 1547 "DPF1,KCNH8,NCKAP5,ARID1A,CSMD3,NDRG2,SLITRK1,ADD3,AXIN2,ADORA1,ADRB2,MTUS1,OSBPL6,C1QTNF1,SEMA6A,C1QTNF4,SPOP,SRPX,BCAR3,BBOX1,OGT,LRCH2,ANK2,ANK3,SEMA7A,PHF12,GAS7,DGKZ,AMER3,APP,AQP4,SEMA4G,CASK,TMEFF1,ARRB2,NUMB,RASL11B,ATP1A3,ATP1B3,ZNF583,B3GALT2,NOL4,ATP6V0A1,BACH1,BCHE,RGS9,NRP2,BMPR1B,CDK5R1,ARHGEF7,CACNA1G,WASF1,BTRC,CACNA1E,DDR1,CACNA2D1,PTBP2,SYT6,SPAG9,CBLN1,LDB2,CCNT1,RGN,AP4M1,ARHGEF2,CDC42,CDH2,CDO1,CRLF1,NUMBL,CFL2,FOXN3,CHN2,CHRM1,KMT2C,EPS15L1,RAB33A,DNAJB5,HECTD1,MAP4K4,CNN3,CNR1,CNTFR,AKAP7,PCYT1B,COL9A1,COL9A2,TBPL1,ZNF521,IGDCC3,ZNF385A,CREB5,AKAP12,CRMP1,HAPLN1,CS,CSNK1E,ATRNL1,SOCS5,RIMS4,PHACTR3,SLITRK5,PPP1R16B,ARHGEF4,ST18,PYGO1,DOCK4,ARHGAP24,RASSF2,DGKB,DAPK1,PITPNC1,ARMCX2,RHOBTB1,CHRDL1,DLG3,DLX1,DMD,NYAP1,USP3,CD99L2,CDON,DPYSL2,ABI1,ECM2,ABCC5,USH1C,PHC2,KLHL5,EFNB3,MBNL2,EGR3,PLXNC1,EIF4G1,EIF4G2,ELAVL2,ING4,ELAVL3,ELAVL4,EN2,LRRC17,SEZ6,EPS8,APC2,ETV1,PIPOX,RTN3,TLR7,RRAGB,EXTL2,KATNAL1,EYA1,HSPA12B,CLVS1,TBC1D16,ZIC4,TUBB4A,SCML2,ATP8A1,FECH,FGFR3,FHL1,UBE2E3,MEX3B,FOXF2,IP6K2,SYNCRIP,SEMA6C,FOXO3,DPYSL4,TACC2,ATP2C1,CELF1,NSG1,DLL3,AP4B1,OGA,FYN,MEGF10,CHL1,GABRG2,GAD1,AHCYL1,ARPP21,SALL3,KIAA1841,GBX2,GCNT2,GDF1,MSTN,GFRA1,PCDH17,PPARGC1A,LYVE1,GJB1,BRD8,RAB30,PCDH11X,STARD3,LOXL3,GPM6A,GPM6B,ATF7,GPR12,EML4,STMN2,GRIA1,GRIK2,GRIK3,GRIN1,GRIN2D,GRM2,GRM3,ZNF496,BTN2A1,PTPRT,GSN,KIF3A,KAT7,SLC2A6,MAP4K5,ATOH8,CELF3,KLF12,BACH2,HMGB1,SCRG1,HPSE2,HMX1,HNRNPK,HSF2,ATCAY,NKD1,ZIC5,RBPJ,DOCK7,USP54,SCRT2,INSM1,LRRTM1,KCND2,KIF5A,KIT,KTN1,L1CAM,STMN1,ARHGAP12,SMAD1,MAP2,MAPT,MAT2A,SHC3,MEF2C,MEIS1,MEIS2,KCTD6,MID1,MITF,AFDN,MMP16,MN1,MPP2,GIT1,SESN3,PTOV1,MXI1,MYT1,HNRNPM,FXYD6,NBL1,NDP,RCOR2,NEUROD1,NEUROD2,NFIX,NFYA,NKX2-2,NNAT,CNOT4,NRCAM,IGSF11,OMG,OPCML,OPHN1,P2RX7,ZNF827,KCNK10,SNTG1,PALM,PAX6,PCDH9,PCSK1,PCSK2,PDE4D,PDGFRA,PDYN,GPR85,TMOD2,PFKFB3,GDAP1L1,SERPINI1,SEMA5B,PIK3CD,PIK3R1,CCSER2,KCTD15,PLEC,SMOX,PLP1,PCDH18,PLXNB3,PDZRN4,PRRX1,NXPH1,PPP2R2B,RASGEF1B,CEP41,PKIA,PROX1,MASP1,PSD,GDPD2,PTH1R,PTPRG,PTPRO,RALGDS,ZCWPW1,RBBP6,ZDHHC14,DUSP15,DPF2,RFX3,RGS3,RLBP1,PBRM1,ZNF532,MYH14,ROBO1,KIRREL1,RORB,RTKN,RTN1,RYR3,FAM192A,SEMA6D,SATB1,SCN3A,HES6,SMPD3,SOX6,TRIM46,SFPQ,SH3BGR,KIF21A,ARX,FBXO11,CNKSR2,PREX2,BTBD3,DHX30,FAM214B,SLC6A1,KANSL3,LGI3,EPC1,CXXC4,SMARCA4,SMARCC2,SMARCE1,SOX2,SOX5,SOX10,SOX11,KDM3A,SP4,KIF1B,LMO3,THSD1,NKAIN2,SS18,ERBIN,ST5,MPRIP,GANAB,SEPT3,GSE1,KLHL7,SYT11,FGD4,SYT4,ASTN2,ANKRD12,MCF2L,TAL1,CNTN2,ADGRL3,FBXW11,KLHL4,ANO4,TCF12,CLASP1,PCDHGA11,RALYL,NSD1,PCDHAC2,TF,ZFPM2,GPR161,GALNT17,TIAM1,HEY1,ZFP91,NR2E1,C5orf64,RBFOX2,TPM1,TPM3,STXBP4,CA14,TSC1,HIRA,UBE2H,UBTF,UCHL1,FLRT1,VAV2,P2RY12,WNT7A,PORCN,SF1,ZIC1,ZIC3,ZNF32,MKRN3,FSTL5,ZNF184,DPYSL5,SMARCAD1,PRTFDC1,LRP8,SLC38A1,RGMA,STMN4,ADAMTS9,NAV3,CAB39L,PCBP4,FAM13C,ST7,RTN4,PAK5,KAT6A,CERS6,JMJD1C" Transcription Factor Binding Site AACTTT_UNKNOWN AACTTT_UNKNOWN 2.22E-16 1.36E-13 3.41E-14 2.38E-13 445 1531 "KCNH8,NCKAP5,ARID1A,CSMD3,ADCY2,DSCAML1,SLITRK1,ADCY6,ADCY8,ADD3,AXIN2,ADRA1B,ADRB2,SLC24A4,OSBPL6,SPARCL1,SEMA6A,ALCAM,BCAR3,PCDH10,UNC79,ALK,MRTFA,BEGAIN,ANK3,MAP4K3,PPFIA2,APBB2,DGKD,APP,CPNE5,CDC14B,TMEFF1,CADPS,DDX3Y,NOL4,DOCK11,ADAM23,ADGRB2,ADGRB3,BCHE,BCS1L,NRP2,ARHGEF7,JAZF1,CACNA1G,BTRC,CA12,CACNA1D,CACNA1E,CACNB2,CALB1,CALB2,CABP7,CALM1,PTBP2,CAMK2A,CAMK2D,SYT6,SPAG9,LDB2,DGKI,ARHGEF2,REPS2,CDH10,LARGE1,MAGI1,NOG,FOXN3,CHN1,CHN2,SYNPR,RAB3C,NDST3,LHX2,KMT2C,CLCN3,NRXN1,SLC24A2,NMT2,CLTA,CNTFR,CNTN1,CABP1,COL4A5,COL9A1,SLC4A7,ACBD5,ZNF521,CP,CREM,CRHBP,CREB5,HAPLN1,RNF14,SNCAIP,PHACTR3,CNTNAP2,SLITRK5,GREB1,CTNND1,CTNND2,ST18,PYGO1,DOCK4,FGFR1OP2,HDAC4,RASSF2,PHYHIP,PITPNC1,ELMO1,FBXL5,KLHL3,DDX46,RHOBTB1,NTM,CHRDL1,DLG2,DLX1,GRIN3A,DMD,HS3ST4,CALN1,CPEB2,TOM1,DYRK1A,ABCC5,EDIL3,PHC2,EFNB3,GPR61,MBNL2,EGR3,PLXNC1,RASA4,EIF4G1,EIF5,ELAVL2,ING4,ELAVL4,EMX2,RCAN2,EPHA5,EPHB1,ERBB2,ERBB4,NCALD,IGSF6,ETV1,EXTL2,EYA1,MRVI1,CLVS1,CACNG3,CACNG2,ACSL4,ZIC4,FCGRT,PPP1R1B,SEC24B,OLFM1,FGF12,FGF13,FGF14,FGFR1,PRKAG2,FOXO3,SORBS1,NSG2,DACH2,FUT9,MPP6,STAG2,GABRA1,GABRA3,GABRB1,GABRG1,ARPP21,SALL3,NEK6,IQGAP2,ATP8A2,MYOZ2,MSTN,SESN1,GFRA1,GHR,PPARGC1A,KIRREL3,NTNG2,GK,GLDC,RAB30,GLS,PCDH11X,GNAS,GNG4,ATF7,GPR22,GPR37,RAPGEF4,GRIK1,GRIK3,NR3C1,GRM1,GRM3,IL1RAPL1,SOX21,CELF3,NXPH3,PACSIN2,HRH3,KLF12,ELOVL5,HMGB1,HPSE2,HTR2A,IGF1,NKD1,ZIC5,IL6ST,SCRT2,LRRTM3,LRRTM1,ITIH2,KCND3,KCNJ3,KCNMA1,KCNN2,KIT,LAMP2,SFXN5,HECTD2,LSAMP,SMAD1,MBNL1,MDFI,LRP1B,SHC3,MEF2C,MEIS1,MEIS2,KITLG,MID1,MITF,MMP16,MN1,MPP2,GIT1,SESN3,CTNNA3,MDGA1,MXI1,MYBPC1,MYT1,NCAM2,NDP,RCOR2,NELL1,NELL2,NEUROD1,NFIA,NHLH1,NKX2-2,NOS1,NOVA1,NPTX2,HCN1,NTRK3,DDR2,NUCB1,NUCB2,ZNF827,ZDHHC22,SNTG1,PAX6,PBX1,PCDHGC3,PCDH8,PCDH9,PCSK1,PCSK5,CDK18,PDE1A,PDE2A,PDE4B,PDE4D,PDYN,GPR85,NLGN3,SERPINI1,PIK3R1,CCSER2,KCTD15,PLCL1,PLIN1,PLP1,PCDH18,PDZRN4,PSAT1,PRRX1,ING3,TNPO2,NXPH1,SH3KBP1,POU3F2,POU3F4,PPP2R2B,PRKAB2,PRKACB,PRKCG,MAPK3,MAPK10,PROX1,RELN,SYTL2,PTHLH,PTK2,ZSCAN32,PTPRG,OXR1,SLC6A15,CRTAC1,RFX3,RFX4,RFX5,RGS3,PRIMA1,RIT2,RORB,FBXW7,RPS6KA2,STK32B,KCNIP1,RYR3,FAM192A,SALL1,SEMA6D,SATB1,SCN4B,LRRTM4,SCN8A,TNFRSF19,SOX6,SCAF8,ITSN1,SH3GL2,PPM1E,MYO18A,SLITRK3,CNKSR2,NLGN1,DZIP1,SLC1A3,BTBD3,SLC6A1,SLC6A11,SEPHS1,SHANK2,SLC12A2,ELMO2,EPC1,CXXC4,SORCS3,TTC17,RIMS1,SNCA,MBD5,SOX1,TRERF1,SOX2,SOX3,SOX5,KDM3A,SP4,SPP1,SPTB,NPAS3,SPART,LMO3,C11orf87,TAB2,CLSTN2,SMOC1,NCDN,ELOVL4,TTBK2,STAC2,STX1A,SYNE2,PLCB1,TAC1,TACR1,TAL1,TCF4,TCF7L2,TRIM2,TCF12,WASHC4,SYNE1,RALYL,NSD1,ZFPM2,CHST8,TIMP4,NR2E1,DAAM2,PARD3,SEZ6L,TPM3,TRPC1,TRPS1,TSC1,SSBP2,TMEFF2,TOM1L2,VIPR2,VLDLR,NSD2,WNT7A,KCNK12,XPO1,ZIC1,ZIC3,CELF4,CA10,PMEPA1,LRP8,RGMA,STMN4,ADAMTS9,SCG2,NAV3,SNX27,FIP1L1,ITM2C,FAM13C,MRPL47,KAT6A,ADAMTSL3,NETO2,NETO1,DPF3,SLC4A10,CPNE4" Transcription Factor Binding Site V$NRSF_01 V$NRSF_01 7.70E-15 4.73E-12 9.45E-13 6.62E-12 48 78 "KCNH8,SLC12A5,FGD2,APBB1,AMER3,ATP2B2,ATP6V0A1,CDK5R1,CALB1,SYT6,CHGA,CHRNB2,BRINP1,ELAVL3,SEZ6,FGF12,PHYHIPL,GABRB3,GABRG2,DNER,RUNDC3A,STMN2,GRIN1,GRM1,CELF3,HTR5A,L1CAM,SCAMP5,DDX25,NEFH,HCN1,OMG,PCSK2,GDAP1L1,PTPRN,RASGRF1,KCNIP2,RPH3A,OGDHL,SNAP25,SCN3B,SST,SYT4,SLC35G2,MGAT5B,VGF,TRIM9,SLC17A6" Transcription Factor Binding Site GGGAGGRR_V$MAZ_Q6 GGGAGGRR_V$MAZ_Q6 7.12E-14 4.37E-11 7.29E-12 5.10E-11 506 1838 "ASIC1,ARID1A,NDRG2,SLITRK1,ADD3,SLC12A5,SORCS1,ADORA2A,MTUS1,TBC1D14,KIAA1324,ALAD,C1QTNF4,ALCAM,SRPX,BCAR3,BEGAIN,AMPD2,AMPH,SEMA7A,FGD2,MAP4K3,PHF12,PKP4,APBB1,DGKZ,PPFIA3,CASK,TMEFF1,SPTBN4,ARHGAP5,ARRB2,CADPS,ASCL1,ASGR1,ZBTB10,CHRD,ALDH4A1,ATP1A1,ATP1A2,ATP1A3,STX16,ATP2A2,NOL4,ADAM15,AZGP1,ADGRB2,BCL2L2,HCN2,FGF17,BMP7,SYNJ1,JAZF1,CACNA1G,WASF1,CACNB2,CAMK2G,TRIM41,SPAG9,KYAT1,USP2,SLC16A4,REPS2,CDH2,KCNAB3,NUMBL,ADGRG1,CHM,CHRM1,PLEKHB1,CASC2,RAB3C,CHRNB2,CPNE6,RAB33A,PPT2,NRXN2,CLTC,DNAJB5,HECTD1,CNN3,CNTFR,PCYT1B,CABP1,COL4A5,COL11A2,MAGED1,ZNF521,ZNF385A,CLOCK,CREM,AKAP12,CRMP1,HAPLN1,NCOR1,CS,SEC24C,MICAL2,CSNK1E,PHACTR3,CNTNAP2,SLITRK5,PPP1R16B,CTNND1,CTNND2,DOCK4,MYADM,SNPH,ARHGAP24,HDAC4,RASSF2,MATR3,PHYHIP,DGKG,BRINP1,PITPNC1,COPS7A,C2CD2L,KLHL3,SV2B,G3BP2,CHRDL1,DLG2,DLG3,DLX1,DMD,DMPK,NYAP1,RPS6KL1,CALN1,CDON,SHANK1,CASP8AP2,DRD1,DSCAM,ARRDC4,DUSP9,DYRK1A,ATL1,PHC2,CNNM1,EFNB3,ABI2,EGR3,PLXNC1,RASA4,EIF4G1,EIF4G2,ELAVL2,ELAVL3,CERCAM,ELAVL4,DCTN4,EMX2,EN2,OLIG2,EPB41L1,RASGRP2,GPHN,SRRM1,EFS,APC2,ETV1,RTN3,EYA1,F5,WAC,CACNG2,ZIC4,TUBB4A,DLC1,FGF11,FGF13,FGF14,FGFR1,HPCAL4,AGAP2,SYNCRIP,FOXO3,FLNC,SYT3,TACC2,SORBS1,CELF1,DLL3,HHIPL1,FYN,STAG2,GABBR1,GABRA3,CHL1,GABRG2,JPH4,GAP43,GART,CPLX2,MYOZ2,GBX2,TUBA8,SESN1,PCDH17,KIRREL3,RUNDC3A,MSL3,PCDH11X,GNAL,LOXL3,GNAO1,GNAS,FERMT2,GPM6B,ATF7,GPR17,ADAP1,STMN2,RAPGEF1,GRIA1,GRIN1,GRIN2D,GRM1,GRM7,ZNF496,GSN,PTPN5,IL1RAPL1,SOX21,PSIP1,CELF3,HPS5,NXPH3,HRH3,FRMD3,KLF12,BACH2,GABARAPL2,AGBL5,HMX1,HNF4G,HNRNPK,TLX1,HPCA,ZDHHC15,USP51,MYLK2,RBPJ,USP54,IGSF1,IL11RA,INSM1,LRRTM1,ITPKA,JAK2,KCNC1,KCNC2,KCND1,KCNH2,KCNJ4,KCNJ10,KCNJ11,KCNMA1,LAMP2,PIK3AP1,MAP4,MAPT,CHST6,ADAM11,MDFI,MDM4,MEIS1,MEIS2,MGAT3,MITF,MOV10,SESN3,MSI1,ADAM22,HS6ST3,MXI1,MYCN,MYH6,MYL3,MYT1,NAP1L2,FXYD6,NCAM1,NCAM2,RCOR2,NEFH,NEUROD2,NF1,NFIX,NKX2-2,NNAT,NODAL,NOS1,CNOT4,NPY,NOVA2,NPTX1,NTRK2,NTRK3,DDR2,ODF2,OGG1,OPHN1,KCNK10,PAK3,PAX6,PCDH9,PCSK2,PDE2A,PENK,NLGN3,GDAP1L1,SERPINI1,TMIE,PLCB2,PLEC,PLIN1,FXYD1,EPN1,SLC25A23,PURG,EPB41L4B,TNPO2,NXPH1,POU3F2,PPP2R2B,PPP2R2C,PPP2R5E,PPP3CA,PRKCG,MAPK3,MAPK7,MAPK10,PROX1,PRPH,CNNM2,PSD,VPS13C,LAMA1,GDPD2,SNRK,PTAFR,PTH1R,PTPRG,RAB3A,RAB5B,RAD17,RALGDS,RAP1GDS1,ZCWPW1,ARID4A,ZDHHC14,GAL3ST4,DPF2,FIGN,RFX3,RFX4,RFX5,RGS3,RGS7,SEC61A2,RPRD1A,ZNF532,TMLHE,CARF,CYB561D1,RORB,RPL15,FBXW7,RTKN,KCNIP2,RXRG,RYR1,SALL1,MAPK12,SATB1,LRFN5,SCN8A,SMPD3,TRIM46,ZNF821,SCAF8,PPM1E,FBXO11,SLITRK3,CNKSR2,NLGN1,DZIP1,EPN2,FAM214B,SLC6A7,SLC6A9,KDM4D,SHANK2,SLC12A4,SLC14A1,GKAP1,SMARCA4,SMARCD3,RIMS1,SNAP25,SNCB,SNCA,KIF13A,SCN3B,SON,TRERF1,SOX5,TSNAXIP1,SOX10,SOX11,SOX15,KDM3A,SP4,NMNAT2,KIF1B,LMO3,TAB2,CAMTA2,LRRC4,ST5,NCDN,ELOVL4,RGL1,STAC2,PHLDB1,SULF2,SYT11,SYNE2,ARC,SYN2,SYT4,TAC1,TAC3,PJA1,ROBO3,TAF9,CNTN2,ADGRL3,KLHL4,TCF4,TCF7L2,TCF12,SYNE1,ARHGEF12,TNS2,AHCYL2,HIF3A,ZFPM2,CHST8,THRA,NR2E1,C5orf64,RBFOX2,TPM2,TPM3,CHST5,ZNF384,TRH,TRPS1,KCNE5,CA14,TSC1,SSBP2,TUB,UBE2H,AMOT,UBTF,FAM181B,VGF,VLDLR,WNT7A,WRN,KLC2,NPDC1,SLC13A3,XPO1,SF1,PCDH20,ZIC2,ZNF24,ZNF32,CRB2,CELF4,FSTL5,CA10,PRTFDC1,SLC38A1,RGMA,PRDM8,ADAMTS9,NAV2,KCNAB1,ITM2C,PCBP4,SLC17A6,ST7,FBXO36,CAMK1G,NETO1,CBLN2,SLC4A10,SENP7,JPH3" Transcription Factor Binding Site TTGTTT_V$FOXO4_01 TTGTTT_V$FOXO4_01 1.63E-13 1.00E-10 1.43E-11 1.00E-10 449 1603 "ASIC2,CLK4,ADARB2,SLITRK1,AXIN2,ADORA1,KLHL13,C1QTNF3,SPARCL1,SEMA6A,ARHGAP20,BIN1,OGT,LRCH2,ANK3,APBA2,APC,APP,CDC14B,SEMA4G,PRX,TMEFF1,RGS20,ARRB2,LINC00173,STK33,ASPA,SLC4A4,STX16,ATP2A2,B3GALT2,ATP6V0A1,DOCK11,RGS9,BCL2L2,BCL7A,FGF17,NRP2,BLM,BSN,WASF1,CACNA1E,CACNA2D1,CALB1,CABP7,SYT6,HIP1R,SPAG9,MAP7,NFS1,CBLN1,KYAT1,LDB2,FMNL3,USP2,CBFA2T2,CD38,AP4M1,REPS2,CDH10,CRLF1,CACNA2D2,CFL2,FOXN3,CHGA,CHN1,CHN2,CASC2,KMT2C,RAB33A,ZFYVE9,SLC24A2,TJP2,QKI,MAP4K4,FHL5,ARHGEF6,CNR1,PCYT1B,COL4A5,COL9A1,SLC4A7,ZNF521,HS3ST5,CPS1,CREM,CREB5,CRMP1,HAPLN1,CRY2,SNCAIP,CSNK1G3,SIPA1L1,SLITRK5,KIAA0040,GREB1,CTNND1,PUM1,DOCK4,HDAC9,RASSF2,KIAA0586,MAML1,IP6K1,BRINP1,PITPNC1,DCT,KLHL3,G3BP2,CHRDL1,DLG2,DLX1,DMD,USP3,CALN1,SLC12A6,GNE,ECM2,DYRK1A,ABCC5,SH3GLB1,MBNL2,EIF4G1,ELAVL2,ING4,ELAVL4,EML1,EMX2,EN2,LRRC17,ENPP6,ERBB4,NCALD,ETV1,EYA1,EZH1,CLVS1,CACNG3,CACNG2,ACSL4,ZIC4,EFEMP1,DLC1,SEC24B,OLFM1,FGF12,FGF13,FGF14,PRKAG2,FOXG1,IP6K2,SEMA6C,EVL,FLT1,AKAP3,DPYSL4,SORBS1,NSG2,TPPP3,MPP6,STAG2,GABRA1,GABRA2,CHL1,GABRG1,GABRG2,GAD2,SALL3,KIAA1841,DNER,ARFIP1,ADAM28,GFRA1,PCDH17,GHR,PPARGC1A,RUNDC3A,BRD8,RAB30,GLRB,MSL3,GNAO1,GNAS,GOLGB1,GPM6A,ATF7,GPR12,GPR22,STMN2,GRIA1,GRIK2,GRIK3,GRIK4,NR3C1,GRM3,GRM5,GRM7,IL1RAPL1,KAT7,SOX21,GUCY1A2,MAP4K5,ATOH8,HAS2,NXPH3,KLF12,HPSE2,GABARAPL2,AGBL5,HNF4G,ZDHHC15,IGF1,IGFBP1,NKD1,ZIC5,NIM1K,USP54,IGSF1,IL6ST,INPP1,ZNF385B,LRRTM3,LRRTM1,KCNA1,KCNC2,KCNJ16,KCNN1,KCNN2,STMN1,HECTD2,SMAD1,MARK1,MARK3,MAT2A,AQP11,MEF2C,MEIS1,MEIS2,KCTD6,KITLG,PPM1L,MITF,GIT1,SESN3,MSI1,PTOV1,SCG3,DDX25,CTNNA3,MDGA1,HS6ST3,MXI1,MYH7,NAP1L1,NASP,NBL1,NCAM1,NDP,NEK1,NEUROD2,NF1,NFIA,NFE2L2,NFIX,NKX2-2,NOVA1,NPTX1,NPTX2,NTRK2,NTRK3,OMG,OPCML,ZDHHC22,KCNK10,PAK3,PALM,PAX6,PBX1,PCDH8,PCSK2,PDCD2,PDE1A,PDE3B,PDE4D,PDGFRA,ENPP2,PENK,PFKFB3,ABCB1,SEMA5B,PIK3C2A,PIK3CD,PIK3R1,PLCB2,FXYD1,PLP1,PCDH18,PDZRN4,PRRX1,SDK2,POU3F4,PPM1B,PPP2R2B,LRRN3,PPP3CB,RASGEF1B,CEP41,PKIA,MAPK3,MAPK8,MAPK10,PROX1,MASP1,APTX,SYTL2,PXK,PTN,PTPRD,ZCWPW1,ARID4A,ZDHHC14,GTDC1,FIGN,RFX4,ZDHHC4,RGS3,RIT2,SEC61A2,NUDT11,ZNF532,ROBO1,KIRREL1,RORB,NEK11,KCNIP2,RTN1,RXRG,SEMA6D,SATB1,LRFN5,SCN3A,LRRTM4,TNFRSF19,SMPD3,ASIC4,SOX6,COPZ1,SGK1,FRMPD1,CPEB3,MYO18A,FBXO11,CLSTN1,ABLIM3,PREX2,BTBD3,EPN2,DHX30,SLC6A1,PKNOX2,SEPHS1,ATF7IP,SLCO1A2,CPEB4,CXXC4,SMARCA4,TTC17,MBD5,FAIM2,TRERF1,SOX2,SOX3,SOX5,FNBP1,KDM3A,SP4,NMNAT2,BEX1,NPAS3,LMO3,SRPK2,CLSTN2,SMOC1,SST,ERBIN,ST5,NCDN,ELOVL4,APOM,TTBK2,KANK1,SULF2,GSE1,FGD4,NUDT10,ANKRD28,SYT4,POPDC3,TAL1,ADGRL3,TCF4,SATB2,TCF7L2,DOCK9,RALYL,NSD1,SIK3,TEK,DNAH7,DICER1,ZFPM2,CHST8,HHIP,THRA,TIAM1,HEY1,TJP1,DAAM2,C5orf64,WBP2,ZNF384,NR2C2,TRPS1,CA14,TSC1,SSBP2,UBE2H,UBE3A,AMOT,UGT8,TOM1L2,VLDLR,NSD2,XRCC4,ZIC1,ZIC2,ZNF24,FSTL5,DPYSL5,PRDM8,NAV3,FIP1L1,CAB39L,SLC17A6,EPM2A,PHTF2,JMJD1C,FXR1,JPH3" Transcription Factor Binding Site TGACATY_UNKNOWN TGACATY_UNKNOWN 1.91E-13 1.17E-10 1.46E-11 1.02E-10 183 534 "ABR,RBM10,CSMD3,ADARB2,ADCY6,ADRA1B,SLC24A4,AP2A2,C1QTNF4,SYT13,APBB2,GAS7,MADD,CDK13,ASGR1,ATP2B3,DOCK11,ADGRB2,BCHE,NRP2,CACNA1G,C5,CA12,CACNA1D,DDR1,CABP7,CALM1,MAP7,CBFA2T2,CDH10,LARGE1,CFL2,FOXN3,KMT2C,CLTB,HECTD1,CNN3,ARHGEF6,COL4A5,AKAP5,RTTN,ZNF521,NECTIN3,CREM,AKAP12,HAPLN1,RNF14,SNCAIP,RGS6,MICAL2,SLITRK5,CTNND1,CTNND2,ARHGAP24,KIAA0586,DAPK3,SPOCK2,PITPNC1,ELMO1,DLG2,DMD,SGK2,CELSR3,EGFR,TENM1,ELAVL4,BSCL2,OLIG2,RCAN2,EYA1,ZIC4,EFEMP1,PPP1R1B,OLFM1,FGF12,FGFR3,FOXG1,SYNCRIP,AKAP3,TACC2,SORBS1,FYN,GABRG1,HBS1L,RAPGEF6,MYOZ2,MSTN,RAB30,GNG3,GPR22,GRIA4,NR3C1,CELF3,ELOVL5,HAPLN2,IGF1,SCRT2,INSM1,KCNH2,KCNK1,KCNN2,LIFR,LIMS1,ARHGAP12,MAP2,MBNL1,ADAM11,LRP1B,MEF2C,MEIS1,MEIS2,MID1,MITF,SESN3,STK32C,MYO7A,MYT1,NAP1L3,NKX2-2,NOVA2,PCSK2,PDE1C,PDE4D,PDGFRA,ENPP2,GPR85,GDAP1L1,PIK3R1,CCSER2,FXYD1,PDZRN4,SCHIP1,NXPH1,POU3F4,PPP2R5C,MAPK10,PTHLH,PTPRD,PYGM,RAP1GDS1,RBBP6,DPF2,RFX4,RORB,PRR5L,SBF1,LRFN5,SCN7A,SCN8A,TNFRSF19,SMPD3,RASA3,SH3BGR,SLN,TTC17,FAIM2,SCN3B,WDTC1,NPAS3,LMO3,SS18,ST5,NCDN,TTBK2,STAC2,FGD4,SYNE2,SYT4,FBXW11,TBL1X,DNAH7,DICER1,TJP1,ZFP91,TPM3,ZIC1,TRIM9,FSTL5,STMN4,KCNAB1,FBXO36,SNX14,DPF3" Transcription Factor Binding Site CAGCTG_V$AP4_Q5 CAGCTG_V$AP4_Q5 3.33E-13 2.05E-10 2.27E-11 1.59E-10 349 1192 "ABR,ASIC2,EMILIN3,NCKAP5,ARID1A,CSMD3,ADCY8,FZD9,CASKIN1,C1QTNF1,SPOP,SRPX,ALK,DOC2A,AMPH,ANK1,ANK2,SEMA7A,APBA2,APBB2,GAS7,ALS2,APP,CASK,CADPS,ASPA,PTCH2,CHRD,ATP1A2,ATP2B3,B3GALT2,NOL4,BACH1,ADGRB3,BCL2L2,BCL7A,FGF17,NRP2,CACNA1G,CDK5R2,DDR1,CACNB2,CAMK2G,SYT6,CAST,HIP1R,CBFA2T2,NEURL1,LRBA,ARHGEF2,REPS2,CDC25B,ARHGAP33,LGI1,CDO1,DLGAP1,NUMBL,GPR37L1,RAB3C,LHX2,RAB33A,DNAJB5,RAB26,ARHGEF6,PCYT1B,CABP1,MAGED1,SMARCAL1,ZNF521,NRG2,NECTIN3,ZNF385A,CPS1,CREM,CRHBP,RNF14,CSF1R,RGS6,IPCEF1,SLITRK5,PPP1R16B,DOCK4,HDAC9,MYADM,SNPH,ARHGAP24,HDAC4,RASSF2,KCTD8,SCRN1,SPOCK2,PABPC5,BRINP1,DCTN1,SV2A,DLG2,DLX1,DMD,HS3ST4,DMPK,USP3,CD99L2,SLC29A4,DMTF1,DRP2,DSCAM,RCAN1,WDPCP,EDN3,SGK2,GPR61,MBNL2,ABI2,GOLGA7,EIF4G2,ELAVL2,ELAVL3,BSCL2,ELN,SEZ6,EFS,ETV1,RASL12,EXTL1,EYA1,MRVI1,CLVS1,CACNG2,ACSL4,TUBB4A,CORO2B,DLC1,FGF1,FGF12,FGF13,FGF14,BAIAP2,FGR,ATP5PD,AGAP2,FLNC,NBEA,SORBS1,UFM1,NSG2,DLL3,TPPP3,TBR1,MEGF10,GABRA3,ARPP21,IP6K3,GAP43,MYOZ2,TUBA8,MSTN,CYP46A1,GHR,NTNG2,RAB30,POLL,GNG3,GPD1,GPM6B,GPR17,GPR34,STMN2,GRIK3,ADAMTS8,GRIN2D,LINC01089,TMEM25,PSIP1,ATOH8,CELF3,PADI2,NXPH3,KLF12,BACH2,HAPLN2,HPSE2,AGBL5,HPCA,SHISA6,HTR5A,IGF1,NKD1,USP54,IL11RA,LRRTM3,LRRTM1,KCNA2,GPR62,KCNH2,KCNJ16,KCNMA1,KCNN2,KCNN3,KIFC3,L1CAM,VWA5A,HECTD2,PIK3AP1,MBNL1,MBP,MEF2C,MEIS2,SCAMP5,MID1,MITF,MOG,MXI1,MYBPC1,MYCN,MYH3,MYL3,MYO7A,MYT1,NACA,RCOR2,NEUROD2,NFIX,NKX2-2,NNAT,NOVA1,NPPA,KSR2,OGG1,OMG,OPCML,PAK3,PCDH9,CDK18,PDE1A,PDE3A,NLGN3,PLCB2,PLEC,PLP1,PCDH18,PLXNB3,PMP22,SPATA6,LRRN3,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PRKCB,PRKCG,MAPK4,MASP1,CNNM2,PSD,BCAS3,SYTL2,PTH1R,PTK2,PYGM,RAB3A,RAB5B,RAD51D,RASGRF2,DPF2,RGR,RGS7,RGS12,RTKN,KCNIP2,RXRG,RYR1,SALL1,SEMA6D,LRFN5,HES6,TNFRSF19,TRIM46,ITSN1,PPM1E,CPEB3,MYO18A,SLC1A7,PREX2,BTBD3,EPN2,SLC8A3,SLC12A2,NAPB,ATF7IP,LGI3,CPEB4,CXXC4,RIMS1,SCN3B,WDTC1,TRERF1,SOX2,SOX5,SOX10,ZSWIM8,KDM4C,SPTAN1,KIF1B,C11orf87,CLSTN2,NCDN,MPRIP,PHLDB1,SEPT3,SUPT5H,VAMP1,TACC1,ANKRD12,SEMA4A,PDLIM2,CNTN2,ADGRL3,TCF4,TCF7,TCF12,DOCK9,CRB1,TIMP4,NR2E1,TNNT1,TP53BP1,RBFOX2,TPM2,TPM3,ZNF384,FNDC5,EIF4ENIF1,UBE2H,SLC35A4,AMOT,UBTF,USP1,VGF,LGI4,USP32P2,SLC26A10,PRDM8,NAV3,PCBP4,PAK5,FBXO36,GJC2,JMJD1C,FXR1" Transcription Factor Binding Site GCANCTGNY_V$MYOD_Q6 GCANCTGNY_V$MYOD_Q6 9.25E-11 5.68E-08 5.68E-09 3.97E-08 222 721 "ABR,ASIC2,CSMD3,ADCY6,AXIN2,SLC12A5,FZD9,MTUS1,GPR158,SPOP,ALK,DOC2A,ANK1,ANK2,FGD2,PKP4,APBB2,PPP4R4,CASK,CADPS,CHRD,ATP1A3,ATP2A2,B3GALT2,NOL4,ADGRB2,BCL7A,FGF17,CDK5R2,CACNB2,CALM1,SYT6,MAP7,SHISA7,USP2,NEURL1,REPS2,CDH10,CRLF1,NUMBL,GPR37L1,SLIT2,RAB33A,NRXN3,CLCN3,NRXN2,ARHGEF6,CABP1,SLC4A8,MAGED1,TBPL1,ZNF521,ZNF385A,CSF1R,PHACTR3,PPP1R16B,HDAC9,SNPH,ARHGAP24,RASSF2,PABPC5,BRINP1,C2CD2L,SV2A,DLG2,DMD,DMPK,SLC29A4,DRP2,HEYL,MBNL2,EIF4G2,ELAVL2,ELAVL3,ELAVL4,SEZ6,GPHN,ETV1,EYA1,CLVS1,TUBB4A,FGF11,FGF12,FGF13,FGFR1,FGR,PRKAG2,NBEA,NSG2,DLL3,FYN,MEGF10,GABRA3,NKX6-2,GALR1,GFAP,GFRA1,PPARGC1A,PCSK1N,GPD1,TDRKH,STMN2,GRIK3,ADAMTS8,GRIN2D,AP4S1,PSIP1,GUCY1A1,ATOH8,CELF3,MUM1,KLF12,AGBL5,HPCA,NEGR1,USP54,LRRTM3,ITGA7,KCND2,GPR62,KCNH2,KCNN2,KCNN3,VWA5A,MBNL1,ADAM11,MPP2,GIT1,MYH3,MYO7A,MYT1,NCAM1,NEFH,NEUROD1,NHLH1,NNAT,NOVA1,NRGN,NTRK3,OPCML,PCDH9,PCSK2,PDE1A,STRN3,FA2H,LRRN3,PPP3CA,PPP3CB,RASGEF1B,PRKCB,PRKCG,PROX1,MASP1,PSD,BCAS3,SYTL2,PTH1R,EML5,RAB3A,RAB5B,OXR1,RGS3,RGS12,RIT2,PBRM1,RTKN,RXRG,TRAPPC13,LRFN5,SCN8A,HES6,TNFRSF19,TRIM46,MYO18A,CNKSR2,PREX2,RADIL,SLC8A3,ATF7IP,SCN3B,TRERF1,SOX2,SOX5,SOX15,SPTB,KIF1B,LMO3,C11orf87,SRPK2,NKAIN2,MPRIP,VAMP1,COBL,SYT4,TACC1,TACR1,ROBO3,ADGRL3,TBL1X,TCF7,TCF12,SYNE1,RALYL,ARHGEF12,HIF3A,CRB1,TJP1,ZFP91,NR2E1,RASD2,TPM2,FNDC5,HIRA,EIF4ENIF1,XPO1,CELF4,DPYSL5,SLC30A3,LMAN2L,PCDH15,PCBP4,DPF3" Transcription Factor Binding Site TGACCTY_V$ERR1_Q2 TGACCTY_V$ERR1_Q2 1.09E-10 6.67E-08 6.07E-09 4.25E-08 250 834 "ABR,ASIC1,NCKAP5,CSMD3,NDRG2,SLITRK1,SORCS1,FZD9,USP31,SLC24A4,AP1B1,MTUS1,NR0B1,AK2,BCAR3,AMPD3,AMPH,CDC42BPA,ANK3,SEMA7A,FGD2,MAP4K3,APBA2,USP37,APP,MADD,TMEFF1,CDK13,ATP1A3,ADAM15,BMPR1B,NAE1,CACNB2,DIRAS1,CAMK2G,CANX,SPAG9,SHISA7,USP2,CD86,SYNGR3,NEURL1,DGKI,NOG,CHGA,LHX2,ZFYVE9,NRXN1,NRXN2,CLTC,CCDC151,CNTFR,SLC25A27,IFFO1,COX4I1,RNF14,CS,PHACTR3,PPP1R16B,RIMS2,BOC,MYADM,SNPH,ARHGAP24,KIAA0586,DCT,DCTN1,FBXL5,COPS7A,PARD6A,SV2A,DLG2,DLX1,DMD,DNM1,DMPK,NYAP1,USP3,DTNB,ABCC5,EEF1A2,ELAVL3,ELAVL4,RCAN2,RASGRP2,KCNMB2,ERBB4,MRPL37,PIPOX,VPS26C,RTN3,DNAJC27,EXTL2,MRVI1,ZIC4,TUBB4A,FGF12,FGFR3,FHL1,HPCAL4,AGAP2,AGAP3,DCTN2,ARFGAP2,TPPP3,MPP6,GABRA3,GABRG2,AHCYL1,DNER,GFAP,PPARGC1A,KIRREL3,NTNG2,GK,TCERG1,HTATSF1,GRIA4,GRIK3,GRM8,LINC01089,MAP4K5,HRH3,KLF12,SYNPO,USP51,HP,DHX35,IDH3A,LRRTM3,ITGA7,ITPKA,CDH20,KCNC1,KCND3,KCNK1,KCNN1,KCNN3,KIF5A,STMN1,LIFR,HECTD2,MEF2C,MEIS2,KCTD6,SCAMP5,PPM1L,MITF,MPP2,CTNNA3,MYL3,NDUFA5,RCOR2,NFIX,NFYA,NNAT,NPTX2,HCN1,OPHN1,SNTG1,PAX6,PCSK5,PCSK2,PDE1A,CDK14,CCSER2,PLEC,FXYD1,PACSIN1,POU3F2,PPM1B,PPP3CC,MASP1,STK32A,PYGM,RAB3A,CRTAC1,RFX5,RGS3,RGS7,ZNF532,PNMA8A,RPE,RPS6KA2,PLPPR3,RTKN,KCNIP2,SATB1,LRFN5,SH3GL2,PPM1E,ARX,SLC4A3,RPH3A,PEX26,BTBD3,PKNOX2,SLC6A8,SLC6A9,RADIL,SMARCC2,OGDHL,MBD5,TRERF1,SOX5,SP2,SPTAN1,RAP1GAP2,LMO3,SMOC1,ST5,NCDN,STAC2,GSE1,VAMP1,ANKRD28,SLC37A2,ASTN2,MLST8,CNTN2,ANO4,TCF7,TCF7L2,ARHGEF12,SIK3,TEK,TF,NACC2,TLL2,TLR4,ZFP91,TP53BP1,TPM2,TPM3,TPM4,NR2C2,FNDC5,KCNE5,UCHL1,BCL2L13,PLPPR2,TBC1D15,VSNL1,SLC30A3,PMEPA1,PCBP4,MRPL47,ADAMTSL3,JMJD1C,DPF3" Transcription Factor Binding Site YGCANTGCR_UNKNOWN YGCANTGCR_UNKNOWN 6.23E-10 3.82E-07 3.19E-08 2.23E-07 50 104 "ASIC2,SEMA7A,DGKD,APP,ARHGAP5,ASCL1,STX16,ADGRB2,SYNJ1,CAST,NRXN3,NRXN1,CLTC,MAGED1,EIF4G2,PLEKHA1,EPHB1,RTN3,FGF13,FGFR1,NOP56,TACC2,OGA,KIAA1841,IL1RAPL1,HPSE2,ZDHHC15,KCNA1,KCNN2,SFXN5,MAT2A,NNAT,NOVA1,CDK14,NLGN3,HMGCLL1,PNMA3,ELP2,SARS,LRFN5,FBXO11,CLSTN1,C11orf87,EPB41L3,ELOVL4,GANAB,VAMP1,VSNL1,KLC2,TRIM9" Transcription Factor Binding Site V$ZIC2_01 V$ZIC2_01 7.28E-10 4.47E-07 3.44E-08 2.41E-07 80 201 "ABR,MTUS1,PCDH10,OGT,PI16,PHF12,PKP4,PRX,PTCH2,NOL4,CALB1,USP2,NOG,CHRNB2,CLTC,DNAJB5,CCDC151,ZNF385A,PPP1R16B,CTNND1,RASSF2,EDN3,KLHL5,RBM12,TENM1,CERCAM,FGF12,FGF13,SYNCRIP,SEMA6C,ATP2C1,SDCBP2,GABRA1,GABRG2,ZMYND11,GHR,GNAO1,GNAS,GPM6A,GRIN2D,HPCA,ZDHHC15,SCRT2,LRRTM3,LRRTM1,KCNA1,KCNC1,KCND2,KCNJ10,KCNK3,MAP4,MYCN,NELL2,NFYA,NKX2-2,OGG1,GPR85,NLGN3,PPP2R5E,MAPK10,RAD52,ZCWPW1,RBBP6,FBXW7,SFPQ,DHX30,TRERF1,FNBP1,SOX15,SMOC1,PDLIM2,TP53BP1,ZNF384,CRB2,CA10,LRP8,PRDM10,LMAN2L,SEMA3B,SLC4A10" Transcription Factor Binding Site YTATTTTNR_V$MEF2_02 YTATTTTNR_V$MEF2_02 1.31E-09 8.01E-07 5.43E-08 3.80E-07 176 558 "NDRG3,SLITRK1,SLC12A5,GPR158,SEMA6A,LRCH2,USP28,PPFIA2,CASK,ARNTL,ASPH,NOL4,ADAM23,ADGRB3,NRP2,BMP7,JAZF1,CAPN3,CAST,USP2,DGKI,CDC27,LGI1,CHN1,RAB33A,NRXN3,SMARCAL1,HS3ST5,CREB5,SIPA1L1,PPP1R16B,CTNND1,RIMS2,HDAC9,HDAC4,MAML1,DGKB,C2CD2L,MED24,DLG2,DMD,DMPK,DTNB,EDN1,EEF1A2,HIPK3,MBNL2,ELAVL4,ETV1,TLR7,EYA1,WAC,FGF12,FGF13,IP6K2,SEMA4D,NBEA,ATP2C1,TBR1,STAG2,GABRA1,SALL3,MYOZ2,GBX2,PPARGC1A,NTNG2,MSL3,KCNMB4,GNAO1,GNAS,GPER1,GPR34,EML4,PLCD4,GRIK1,GRIK2,GRIN2D,GRM8,LINC01089,IL1RAPL1,MAP4K5,HAS2,KLF12,HNF4G,HSF2,IGFBP1,ZIC5,IL6R,ZNF385B,ITGA7,KCND3,KCNJ9,KCNJ11,KCNN1,KCNN3,KTN1,LAMA2,LIFR,MARK1,ADAM11,PPM1L,MITF,SCG3,MXI1,MYH6,MYL3,MIR4697HG,MYO9A,NCAM1,NDP,NFIA,NFIX,OMG,OPCML,ZDHHC22,DPY19L2P2,PCDH9,PCSK1,PDGFRA,ENPP2,PGAM2,RETREG1,FXYD1,EPN1,PDZRN4,PRRX1,PPARA,PPM1B,PEX5,RASGRF1,RFX3,RFX4,YJEFN3,KCNIP2,ITSN1,PPM1E,FBXO11,RPH3A,EPN2,SLC8A3,SLC14A1,SLN,SNAP25,KIF13A,SOX1,SOX2,FNBP1,SP4,ARHGAP26,SPTB,LMO3,LRRC4,RGL1,ADHFE1,ANKRD28,SYT4,CNTN2,AGTPBP1,CLASP1,SYNE1,PCDHGA1,PCDHA6,SIK3,ZFPM2,C5orf64,KAT6B,TNNT1,TSC1,P2RY12,SLC30A4,HRASLS,DOCK8,JMJD1C,SSPN,FXR1,RNF146" Transcription Factor Binding Site CTTTGA_V$LEF1_Q2 CTTTGA_V$LEF1_Q2 1.38E-09 8.46E-07 5.43E-08 3.80E-07 281 981 "KCNH8,ABR,NCKAP5,ARID1A,ADD3,SORCS1,USP31,SLC24A4,OSBPL6,WDR35,OSBPL8,ALCAM,ABCD2,ARHGAP20,AMPD3,LRCH2,ANK3,MAP4K3,APBB2,GAS7,ALS2,PPFIA3,SEMA4G,CASK,CADPS,ASPH,PTCH2,SLC4A4,DOCK11,ADGRB2,FGF17,NRP2,BMP7,CA4,CA12,CABP7,SPAG9,USP2,CBFA2T2,CDC25B,NOG,CACNA2D2,FOXN3,CHGA,CHN2,SYNPR,NDST3,LHX2,ZFYVE9,NRXN1,CLTC,DNAJB5,MAP4K4,ARHGEF6,CNTFR,PCYT1B,COL11A2,ZNF521,IGDCC3,CPS1,CDC42BPB,CREM,CREB5,HAPLN1,RNF14,CS,SNCAIP,CSNK1G3,CTNND1,PHYHIP,SPOCK2,DCT,MYEF2,ELMO1,SV2A,CHRDL1,DLX1,DMD,NYAP1,USP3,DSCAM,EDN3,EIF4G1,EIF4G2,EIF5,TENM1,ELAVL2,ELAVL4,BSCL2,ERBB4,NCALD,ETV1,EYA1,GMPR2,MRVI1,ZIC4,SCML2,DLC1,PPP1R1B,SEC24B,FGF14,FGFR3,NBEA,SORBS1,TBR1,AP4B1,MPP6,STAG2,GABRG2,AHCYL1,ARPP21,GBX2,GFRA1,PPARGC1A,TCERG1,GLI2,GLYR1,RAB30,GNG3,GOLGB1,GPM6A,EML4,LINC01089,IL1RAPL1,SOX21,PSIP1,MAP4K5,HAS2,NXPH3,SCRG1,AGBL5,ICA1,NKD1,SCRT2,LRRTM3,LRRTM1,ITGAM,TTYH2,LAMP2,LIFR,LMO1,SMAD1,MAOB,MBNL1,MBP,MEF2C,MEIS1,MEIS2,KCTD6,KITLG,MID1,PPM1L,MITF,MOV10,MPP2,SESN3,SCG3,HS6ST3,MYL3,NDP,RCOR2,NEUROD1,NFIX,NINJ2,NPPA,DDR2,ODF2,OGG1,OPCML,ZNF827,SNTG1,PAX6,PCDHGC3,PCDH8,PCSK1,PDE1A,ENPP2,PDYN,PFKFB4,PIK3R1,KCTD15,PLEC,PCDH18,MTRF1L,PMP2,PRRX1,NXPH1,POU3F4,PPP2R2B,LRRN3,PPP2R5C,PRKCB,MAPK10,PROX1,SYTL2,PTHLH,PXK,PTPRO,ACSS3,KHDRBS2,RET,FIGN,RFX3,RFX4,RGS3,RGS12,RLBP1,PBRM1,CYB561D1,ROBO1,PGBD4,FBXW7,EMID1,RTN1,FAM192A,SALL1,SEMA6D,SATB1,SCN2B,SCN3A,TNFRSF19,SOX6,ARX,CNKSR2,URGCP,SLC6A9,KBTBD4,SLC14A1,ELMO2,SLN,SMARCC2,SNAP25,SOX5,KDM3A,SP4,SPTAN1,CLSTN2,MESP1,NCDN,ELOVL4,RGL1,STAC2,STX1A,KLHL7,SYNE2,ANKRD28,TCF4,TCF7,TCF7L2,TRIM2,TCF12,PCDHGA4,RALYL,NSD1,HIF3A,TF,GALNT17,HEY1,TLL2,NR2E1,HEY2,TP53BP1,UBE3A,VSNL1,ZIC1,TRIM9,CELF4,SLC30A3,WNK1,PMEPA1,PRDM2,LRP8,RGMA,SCG2,NAV2,PCBP4,MPPE1,SLC17A6,DPF3,AP3B2,CPNE4" Transcription Factor Binding Site V$RORA1_01 V$RORA1_01 1.42E-09 8.69E-07 5.43E-08 3.80E-07 79 200 "ABAT,NCKAP5,NDRG2,SORCS1,ARNTL,ASPH,B3GALT2,NOL4,CACNA1A,CACNB2,CAMK2B,SPAG9,LDB2,KCNAB3,LARGE1,NOG,SLC22A6,CNTFR,SLC25A27,SLC4A7,RGS6,CTH,HDAC9,KIAA0586,SPOCK2,CHRDL1,DTNB,EFNA3,RASA4,ELAVL4,CDHR1,RTN3,EXTL2,MRVI1,ACSL4,IP6K2,CAMKK2,MPP6,GK,LPAR4,GRIA1,GRIK3,GRM1,PSIP1,KIF5A,MATK,MEF2C,MYL3,NELL2,NFYA,HCN1,SNTG1,PCDH18,PACSIN1,RAB3A,KHDRBS2,FBXW7,RYR1,SATB1,ARX,SLA,URGCP,BTBD3,SLC8A3,SCMH1,SOX15,SPTAN1,LMO3,MPRIP,TTBK2,STAC2,VAMP1,CNTN2,TCF7,SYNE1,GPR161,TPM3,JMJD1C,SOCS4" Transcription Factor Binding Site GGGTGGRR_V$PAX4_03 GGGTGGRR_V$PAX4_03 2.16E-09 1.32E-06 7.79E-08 5.45E-07 301 1068 "DPF1,ABR,ASIC2,ASIC1,NDRG2,ADD1,ADD3,SLC12A5,ADORA2A,MTUS1,SEMA6A,SPOP,BCAR3,MRTFA,BEGAIN,ANK2,SEMA7A,MAP4K3,PPFIA2,ANXA7,CPNE5,AQP4,IGDCC4,SPTBN4,ARHGAP5,CHRD,RASL11B,ATP1A3,NOL4,DOCK11,ADGRB2,FGF17,LDHD,BMP7,BTK,AP1M1,CACNA1G,GPC2,CDK5R2,CACNA1A,CACNA1D,CACNA1E,TRIM41,SYT6,CAST,SPAG9,KYAT1,FMNL3,USP2,ARHGEF1,CD38,ARHGEF2,CRLF1,NUMBL,FOXN3,CHRM1,CPNE6,COL9A1,COL11A2,MAGED1,ACBD5,ZNF521,NRG2,ZNF385A,HAPLN1,CS,PHACTR3,DZIP3,CTNND1,CTNND2,ARHGAP32,FGFR1OP2,RASSF2,KIAA0586,PHYHIP,PITPNC1,DCTN1,C2CD2L,CHRDL1,DLG2,DLG3,DLX1,HS3ST4,DMPK,HS3ST2,NYAP1,SLC12A6,DPYSL2,ABI1,DYRK1A,EEF1A2,EFNB3,ABI2,EGR3,EIF4G1,EIF4G2,ELAVL2,ELAVL3,CERCAM,ELAVL4,ELN,DCTN4,EN2,ENO2,DMTN,RASGRP2,SEZ6,EPHB1,NCALD,RTN3,HSPA12B,CLVS1,WAC,CACNG2,PTK2B,ZIC4,TUBB4A,FGF11,FGFR1,FHL1,MEX3B,HPCAL4,SYNCRIP,SEMA6C,FLNC,FLT1,FOLR2,TPPP3,ZNF512,OGA,FYN,STAG2,GABRG2,IQGAP2,GAP43,ARFIP1,SESN1,C1QL1,RUNDC3A,RAB30,PCSK1N,GNAO1,FERMT2,GPM6B,ATF7,GPR17,STMN2,PLCD4,GRIK1,GRIK3,GRIN2D,NR3C1,GRM3,GRM7,AP4S1,ATOH8,KLF12,BACH2,HPSE2,AGBL5,HNRNPK,NEGR1,HSD17B1,IGF1,ZIC5,IGSF1,ITPKB,KCNA1,KCND3,KCNH2,KCNN3,MAP4,MAPT,MBNL1,ADAM11,MEIS2,MGAT3,SCAMP5,MN1,MOV10,MPP2,MSI1,HS6ST3,MXI1,MYL3,FXYD7,NBL1,NCAM2,RCOR2,NEUROD2,NFIX,NHLH1,CNOT4,ODF2,OGDH,OPRL1,ZNF827,KCNK10,PAX6,PBX1,PCSK2,GPR85,ZDHHC8,NLGN3,SERPINI1,PLEC,PLXNB3,PURG,PMP22,TRHDE,STRN3,PRRX1,TNPO2,NXPH1,POU3F4,PPM1B,PPP2R2B,PKIA,PRKCG,MAPK3,PRPH,PSD,GDPD2,PTPRN,PYGM,ZCWPW1,ZDHHC14,CRTAC1,RPRD1A,LGI2,ZNF532,ELP2,EMID1,RTKN,SALL1,LRFN5,LRRTM4,SCN8A,TRIM46,ZNF821,MYO18A,SLITRK3,FAM214B,SLC6A11,RADIL,SLC9A5,SLC12A4,EPC1,SCN3B,TRERF1,SOX10,SOX15,KDM3A,SP2,SP4,ARHGAP26,SPTAN1,SPTB,C11orf87,TAB2,POGZ,NCDN,SEPT3,GSE1,PJA1,ROBO3,TAL1,CNTN2,TCF4,CLASP1,ARHGEF12,ZFPM2,FBXL16,THRA,HEY1,ZFP91,TP53BP1,SEZ6L,TPM3,FNDC5,TUB,EIF4ENIF1,UBE3A,AMOT,WRN,KCNK12,LGI4,ZIC2,CELF4,DPYSL5,SH3GLB2,CA10,RGMA,STMN4,PRDM10,ADAMTS9,SEMA3B,PCBP4,RTN4,FBXO36,JMJD1C" Transcription Factor Binding Site TAATTA_V$CHX10_01 TAATTA_V$CHX10_01 3.30E-09 2.03E-06 1.13E-07 7.88E-07 200 659 "NCKAP5,ADARB2,DSCAML1,SLITRK1,ADD3,MTUS1,OSBPL8,ALK,PITPNM2,OGT,DPP10,SEMA7A,SEMA4G,CASK,ARNTL,ARRB1,RASL11B,ATP2A2,NOL4,BACH1,BMPR1B,ARHGEF7,C5,GPC2,CA4,CANX,LDB2,ARHGEF2,CDH10,CDO1,FOXN3,SLC24A2,CNN3,WHRN,COL4A5,COL11A2,ACBD5,CREB5,HAPLN1,CS,FEZ2,SOCS5,SLITRK5,CTNND1,CTNND2,PITPNC1,ELMO1,COPS7A,MED24,DLX1,DMD,CALN1,DSCAM,RCAN1,WDPCP,ELAVL2,ELAVL4,EMX2,SEZ6,ERBB4,ETV1,EYA1,CACNG2,ZIC4,TUBB4A,DLC1,PPP1R1B,FOXG1,FOXF2,AGAP3,ZBED3,ARFGAP2,TBR1,FYN,STAG2,CHL1,ARPP21,SALL3,GAP43,GBX2,MSTN,KIRREL3,NTNG2,GNAO1,GNAS,GPR22,LPAR4,STMN2,ADAMTS13,GRM8,IL1RAPL1,WIF1,BACH2,IFI16,NIM1K,SCRT2,ZNF385B,LRRTM1,CDH20,KCNK2,KCNMA1,KCNN3,LIMS1,LMO1,SMAD1,MBNL1,ADAM11,MEF2C,MID1,MITF,MYBPC1,MYT1,NDP,NELL2,NEUROD1,NFIX,NFYA,NKX2-2,NOVA1,OGG1,SNTG1,PAX6,PCSK2,PDE1A,PDGFRA,PENK,SEMA5B,KCTD15,PCDH18,PDZRN4,PRRX1,NXPH1,POU3F4,PPP2R2B,CEP41,PTH1R,PTPRO,RAB5B,FIGN,RFX3,RGS12,ROBO1,RORB,ELP2,SALL1,LRFN5,PPM1E,SLITRK3,BTBD3,SLC9A5,ELMO2,CPEB4,SLN,CMTR2,SOX5,UNC5B,ZNF423,ARHGAP26,LMO3,SRPK2,CLSTN2,POGZ,SMOC1,EPB41L3,LRRC4,STAC2,SULF2,GSE1,SYNE2,ADAMTS17,ARC,TAC1,POPDC3,PJA1,ROBO3,TAL1,KLHL4,PCDHB15,PCDHB3,PCDHA6,CHST8,ITGB3BP,HHIP,THRA,DAAM2,C5orf64,KAT6B,TP53BP1,RBFOX2,SEZ6L,VLDLR,WNT7A,ZIC1,PMEPA1,PRDM8,FIP1L1,PHTF2,ADAMTS10,SSPN,JPH3" Transcription Factor Binding Site GTTRYCATRR_UNKNOWN GTTRYCATRR_UNKNOWN 4.91E-09 3.02E-06 1.59E-07 1.11E-06 56 128 "CASKIN1,DOC2A,ANK2,ALS2,NUMB,ATP1A3,CAMK2A,SYT6,PPT2,CALY,HDAC4,SPATA2,ELMO1,SHANK1,KATNAL1,TBC1D16,TUBB4A,HPCAL4,AGAP2,FYN,CHL1,GDF1,POLL,PCSK1N,GPR17,GRIN2D,KIF3A,NIM1K,MPP2,FXYD6,NOS1,NLGN3,FXYD1,PDZRN4,SPATA6,PRKCG,MAPK10,PSD,RFX4,ZNF532,PNMA8A,KCNIP2,PPM1E,DHX30,FAM214B,FAIM2,SOX3,LMO3,ST5,NCDN,FGD4,FNDC9,CHST8,TP53BP1,ZNF24,SMARCAD1" Transcription Factor Binding Site CAGNWMCNNNGAC_UNKNOWN CAGNWMCNNNGAC_UNKNOWN 6.63E-09 4.07E-06 2.04E-07 1.42E-06 37 71 "CSMD3,SLC12A5,FGD2,CDK5R1,CACNA1B,CALB1,SYT6,CHGA,CHGB,CHRNB2,BRINP1,ELAVL3,PHYHIPL,GABRG2,DNER,GRIN1,GRM1,CELF3,HPCA,L1CAM,NEFH,OMG,SCHIP1,PTH1R,PTPRN,KCNIP2,TNFRSF19,RPH3A,OGDHL,SCN3B,BEX1,GSE1,SYT4,SLC35G2,MGAT5B,SLC17A6,JMJD1C" Transcription Factor Binding Site TGACAGNY_V$MEIS1_01 TGACAGNY_V$MEIS1_01 7.41E-09 4.55E-06 2.17E-07 1.52E-06 195 645 "DPF1,RBM10,ADCY5,ADCY8,FZD9,ADRA1B,CASKIN1,AK2,SPARCL1,PCDH10,UNC79,CDC42BPA,DPP10,PHF12,APBB1,CASK,LINC00173,ASCL1,ATP1A3,B3GALT2,NOL4,ADGRB3,MTMR3,SLC25A14,CAST,SPAG9,USP2,ARHGAP33,CHN2,KMT2C,NRXN1,CLTC,TJP2,DNAJB5,MAP4K4,TBPL1,NRG2,CDC42BPB,CREB5,RNF14,RGS6,CSF3R,DOCK4,KCTD8,SPOCK2,ELMO1,RHOBTB1,WDR20,DMD,DMTF1,DSCAM,PHC2,SGK2,ELAVL2,ELAVL4,EML1,OLIG2,GPHN,NCALD,ETV1,EXTL2,EYA1,CACNG3,PTK2B,TUBB4A,PPP1R1B,FGF12,FGF13,CAMSAP1,SEMA6C,FOXO3,NOP56,ARFGAP2,CAMKK2,ATP2C1,NSG2,GALNT15,GAD1,IP6K3,MYOZ2,GATM,SESN1,PCDH17,C1QL1,PPARGC1A,GNAO1,GPM6A,GRB10,GRIA1,GRIK1,GRIK3,AP4S1,HPS5,KLF12,BACH2,ELOVL5,MYLK2,IL11RA,LRRTM3,KCNH2,LMO2,LSAMP,PACRG,MAP2,MBNL1,MEIS1,MEIS2,KITLG,MITF,MN1,MYBPC1,MYT1,NCAM1,RCOR2,NEUROD2,NNAT,CNOT4,NPPA,NRGN,HCN1,ODF2,KCNK10,SNTG1,PAK3,PAX6,PCDHGC3,PDE1A,PDGFRA,ENPP2,PFKFB3,TMIE,PLCB2,PLP1,PDZRN4,STRN3,SDK2,PPP2R2B,PTPA,PPP2R5C,PPP3CA,PPP3CB,SYTL2,PTN,RFX3,PBRM1,HUNK,KCNIP2,RXRG,FAM192A,SEMA6D,LRRTM4,HES6,TNFRSF19,ZNF821,SHANK2,SLC12A2,ELMO2,TRERF1,SOX2,SOX5,KDM4C,SPTB,KIF1B,SRPK2,TAB2,CLSTN2,SMOC1,NCDN,TACC1,ANKRD12,SEMA4A,CNTN2,TCF7L2,ARHGEF12,TNS2,SIRT1,TIAM1,NR2E1,TPM2,EIF4ENIF1,UBE2H,UBE3A,PITPNB,FLRT1,PLPPR2,VLDLR,XPO1,SLC30A4,MDH1B,NAV3,NAV2,PCBP4,KAT6A,FXR1,DPF3" Transcription Factor Binding Site V$E47_02 V$E47_02 1.66E-08 1.02E-05 4.64E-07 3.25E-06 76 199 "ABR,ASIC2,DSCAML1,KLHL13,MRTFA,AMPH,SEMA4G,NOL4,CALB1,SHISA7,NUMBL,CHRM1,PLEKHB1,RAB33A,SNCAIP,RIMS2,HDAC9,ARMCX2,RHOBTB1,PARD6A,DMD,DMPK,DSCAM,DUSP9,ELAVL2,FGF11,FGF13,NSG2,CELF1,GATM,GFAP,PCDH17,GRIA1,AP4S1,HAPLN2,USP54,KCNA4,KCNN2,LMO2,MEF2C,MEIS2,MMP16,GIT1,NPTX2,PDE4B,CDK14,PLEC,STRN3,POU3F2,PPP2R2B,LRRN3,CEP41,SYTL2,ZNF532,TRAPPC13,MAPK12,HES6,ASIC4,MYO18A,SLITRK3,BTBD3,SNAP25,TRERF1,UNC5B,NCDN,GSE1,FGD4,SYNE2,TAL1,PCDHA6,PCDHA1,THRA,TPM2,CELF4,JMJD1C,JPH3" Transcription Factor Binding Site AAAYRNCTG_UNKNOWN AAAYRNCTG_UNKNOWN 2.02E-08 1.24E-05 5.40E-07 3.78E-06 108 315 "ARID1A,DSCAML1,ADD3,APBB2,ASPH,ATP1A2,ADGRB3,BMPR1B,CACNB2,HIP1R,FMNL3,CDH2,CHRM1,B4GALT6,CLTC,CNTN1,PCYT1B,COL4A5,ZNF521,FGFR1OP2,MAML1,DGKB,SPOCK2,PLEKHM1,KLHL3,DMD,DYRK1A,PHC2,EIF5,RGS17,EMX2,ERBB4,EYA1,ZIC4,FGF12,FGFR1,FOXG1,IP6K2,MPP6,STAG2,GABRA3,PCDH17,DHRS4,RAB30,RAPGEF4,IL1RAPL1,AP4S1,SOX21,ATOH8,HPSE2,IGF1,KCNN3,VWA5A,PACRG,MAP2,MAP6,SHC3,MEIS1,KITLG,MID1,SESN3,NEK1,NTRK2,OMG,PDGFRA,GPR85,PLEC,PCDH18,PDZRN4,STRN3,PTPA,PPP2R5E,PPP3CA,PRKCG,PTH1R,RAB5B,ARID4A,TSPY26P,KCNIP2,RTN1,SEMA6D,SCN8A,ARX,MYO18A,BTBD3,SLC6A1,NAPB,EPC1,TTC17,SCN3B,SOX5,LRRC4,NCDN,GSE1,FGD4,FNDC9,ANKRD28,ANKRD12,PDLIM2,ZFPM2,ZFP91,TRPS1,SSBP2,USP1,ZIC1,NAV3,NAV2,RNF146" Transcription Factor Binding Site RTAAACA_V$FREAC2_01 RTAAACA_V$FREAC2_01 2.14E-08 1.31E-05 5.47E-07 3.83E-06 218 746 "ASIC2,CSMD3,NDRG2,AXIN2,C1QTNF3,UNC79,BIN1,DPP10,ANK2,SEMA4G,ARNTL,CADPS,LINC00173,ASCL1,ASPA,ZBTB10,ALDH4A1,STX16,ADGRB3,CASTOR3,CACNB2,SYT6,CBFA2T2,AP4M1,ARHGEF2,LGI1,CLGN,CFL2,FOXN3,CASC2,ZFYVE9,PPT2,SLC24A2,NGEF,ARHGEF6,PCYT1B,ZNF521,CREB5,SNCAIP,CSNK1G3,PHACTR3,SLITRK5,CTH,SCRN1,SPOCK2,PITPNC1,ELMO1,DLX1,DMD,NYAP1,USP3,SLC12A6,RCAN1,EDN1,GPR61,MBNL2,TENM1,EML1,EMX2,EN2,ERBB2,ERBB4,ETV1,EYA1,MRVI1,EZH1,CACNG2,EFEMP1,DLC1,FGF12,FGF14,MEX3B,FOXG1,IP6K2,FOXO3,NSG2,MPP6,OGA,FYN,SDCBP2,STAG2,RAPGEF6,SALL3,STARD10,GCNT2,GFRA1,PPARGC1A,BRD8,GLYR1,RAB30,GNAO1,GPM6A,ATF7,GRIK2,GRIK3,ADAMTS13,NR3C1,MAP4K5,KLF12,BACH2,GABARAPL2,SYNPO,HSF2,IGF1,NIM1K,IL6ST,ZNF385B,KCNA1,KCNA4,KCNH2,KCNN3,LIFR,ARHGAP12,SMAD1,SMAD9,MATN2,MBNL1,MEIS1,MID1,MITF,MMP16,MN1,SESN3,MYT1,NDUFA5,NEUROD1,NF1,NFIX,NFYA,NINJ2,NTRK3,P2RX7,PALM,PBX1,PCDH9,PCSK1,PCSK5,PDE1A,ENPP2,CDK14,ABCB1,NLGN3,PIK3C2A,RETREG1,KCTD15,PLCB2,SMOX,EPN1,PCDH18,PDZRN4,ING3,POU3F2,POU3F4,PPP2R2B,PPP3CA,RASGEF1B,PKIA,MAPK3,MAPK10,PROX1,BCAS3,PTH1R,PXK,RAB5B,ARID4A,ZNF532,ROBO1,RORB,FBXW7,SEMA6D,SCN4B,TNFRSF19,SCAF8,KIF21A,ARX,CPEB3,CLSTN1,ABLIM3,PREX2,BTBD3,ABTB1,SNAP25,WDTC1,TRERF1,SOX2,SOX5,ZNF423,LMO3,SRPK2,NCDN,GSE1,ANKRD28,PJA1,TCF4,SATB2,TCF7,TCF7L2,TRIM2,TCF12,TNS2,TEK,CRB1,HHIP,THRA,TIAM1,C5orf64,TRPS1,TSC1,UBE2H,BCL2L13,KLC2,NPDC1,TRIM9,MKRN3,SH3GLB2,FAM13C,KAT6A,SLC4A10" Transcription Factor Binding Site V$MYOD_01 V$MYOD_01 3.10E-08 1.91E-05 7.62E-07 5.33E-06 77 205 "CSMD3,KIAA1324,SORCS2,SPOP,ALCAM,DGKD,BACH1,CACNB2,CALB1,CAMK2A,SHISA7,CBFA2T2,ARHGEF2,CRLF1,CACNA2D2,RAB26,COL11A2,CALY,RIMS2,ELMO1,USP3,CALN1,DRP2,DSCAM,PLXNC1,ELAVL4,EML1,ETV1,PTK2B,FGF11,AGAP3,NSG2,CELF1,GABRA3,GCK,PPARGC1A,GNAS,GPR37,GRIK5,PSIP1,HRH3,HPSE2,IGF1,USP54,KCNB1,KCNN2,KCNN3,KTN1,MT3,NHLH1,NTRK2,OMG,EPB41L4B,CEP41,CNNM2,PSD,GDPD2,RXRG,HES6,ITSN1,FRMPD1,ABLIM3,SLC6A7,SHANK2,KDM4C,NCDN,GSE1,SYT4,GALNT17,WBP2,FNDC5,KCNE5,EIF4ENIF1,USP32P2,CA10,SCG2,GAL3ST3" Transcription Factor Binding Site YNGTTNNNATT_UNKNOWN YNGTTNNNATT_UNKNOWN 4.63E-08 2.84E-05 1.09E-06 7.65E-06 99 286 "ADARB2,AXIN2,KLHL13,PCDH10,DPP10,PKP4,ASPA,NUMB,ATP2A2,CACNA1G,CACNA1E,CALM1,CBLN1,NOG,FOXN3,CHN2,LHX2,NRXN3,SLC24A2,PCYT1B,COL9A1,ZNF521,ATRNL1,CNTNAP2,CTNND1,CYBB,DOCK4,DCTN1,ELMO1,CHRDL1,GRIN3A,DMD,HS3ST4,DSCAM,KCNMB2,ETV1,EYA1,ACSL4,DLC1,TPPP3,STAG2,GABRA4,CHL1,GABRG2,GNAO1,GRIN1,KAT7,HAPLN2,INSM1,MITF,MXI1,NEUROD2,NFIX,NKX2-2,NTRK3,OGG1,OMG,PBX1,PDE1A,PDE1C,ENPP2,PIK3CD,PIK3R1,KCTD15,PDZRN4,PPP2R5E,CEP41,SYTL2,PTPRD,RASGRF1,FIGN,RGS3,RORB,RYR1,SATB1,CPEB4,KIF13A,WDTC1,SOX2,SOX5,SOX10,SP4,LMO3,TAB2,LRRC4,PLCB1,TAL1,TPCN2,TCF12,RALYL,ZFPM2,TNR,TPM2,ZIC2,ZIC3,CELF4,CA10,JMJD1C,SLC39A12" Transcription Factor Binding Site V$E47_01 V$E47_01 5.69E-08 3.50E-05 1.30E-06 9.06E-06 76 204 "EMILIN3,KLHL13,SORCS2,SPOP,DGKD,ARRB2,CHRD,CALB1,KALRN,CAMK2A,CAMK2G,NEURL1,CDH2,NUMBL,CACNA2D2,DNAJB5,RAB26,AKAP12,GIT2,CHRDL1,DRP2,DSCAM,DUSP9,ELAVL3,ELAVL4,EPB41,PTK2B,FLNC,SORBS1,NSG2,GABRG2,PCDH17,GJB1,GK,GNAS,GPM6B,GPR37,PSIP1,CELF3,HRH3,RBPJ,SCRT2,KCNB1,KCNH2,KCNJ4,KCNMA1,MYO7A,NBL1,NODAL,PAK3,PLEC,EPB41L4B,PPP2R2B,CNNM2,TTC13,RAB5B,KHDRBS2,ZNF532,KCNIP2,RXRG,RYR1,HES6,ABLIM3,TTC17,SPTAN1,LMO3,GSE1,VPS13A,PLCB1,NSD1,THRA,EIF4ENIF1,KCNK12,DPYSL5,SH3GLB2,NETO2" Transcription Factor Binding Site V$E12_Q6 V$E12_Q6 6.45E-08 3.96E-05 1.37E-06 9.61E-06 75 201 "SLC12A5,MTUS1,KLHL13,SORCS2,DOC2A,ANK2,NOL4,CALB1,KALRN,CAMK2A,CANX,MAP7,USP2,NEURL1,CDH2,DNAJB5,RAB26,PHACTR3,ARHGAP24,RASSF2,ELMO1,WDR20,CHRDL1,DMPK,CALN1,DSCAM,HEYL,PTK2B,CORO2B,FGF11,PRKAG2,AGAP3,NSG2,DLL3,FYN,GFAP,GFRA1,GNAS,GPD1,GPM6B,GPR37,RAPGEF4,GRIA1,NEGR1,MYLK2,KCNB1,KCNN3,GIT1,MT3,MDGA1,NBL1,NHLH1,NTRK2,NTRK3,PLEC,PPARA,CNNM2,GDPD2,MYH14,HES6,SELL,ABLIM3,TTC17,SPTB,NKAIN2,SYT4,ROBO3,RALYL,ARHGEF12,HIF3A,TPM3,KCNK12,CELF4,SCG2,PCDH15" Transcription Factor Binding Site V$CDPCR3HD_01 V$CDPCR3HD_01 6.49E-08 3.98E-05 1.37E-06 9.61E-06 73 194 "DPF1,ASIC1,CSMD3,SLC12A5,TBC1D14,DPP10,LINC00173,NOL4,CAMK2D,SLC25A14,CBFA2T2,NOG,FOXN3,CPNE6,RAB33A,CREM,HAPLN1,BRINP1,DLG2,DLG3,DMD,CALN1,DPYSL2,DRP2,WDPCP,EEF1A2,EGR3,EIF4G2,ETV1,EYA1,DACH2,FYN,STAG2,JPH4,GART,GCK,NTNG2,STMN2,GRIK4,IL1RAPL1,HNF4G,TLX1,NEGR1,ITGA7,KCNA1,KCND1,KCNH2,SMAD1,MEIS1,MN1,GIT1,MYT1,NFIX,NKX2-2,NOVA1,ZNF827,PDE1A,SERPINI1,RASGRF1,GAL3ST4,RFX4,ROBO1,FBXW7,RPH3A,BTBD3,SON,SOX5,CLSTN2,TCF7L2,MGAT5B,VGF,CELF4,ST7" Transcription Factor Binding Site YCATTAA_UNKNOWN YCATTAA_UNKNOWN 1.03E-07 6.29E-05 2.10E-06 1.47E-05 144 462 "TTYH1,CSMD3,SORCS1,ADRA1B,KLHL13,CPNE5,SEMA4G,TMEFF1,NOL4,DOCK11,ADGRB2,JAZF1,CA4,KALRN,LARGE1,FOXN3,CHM,CASC2,ARHGAP22,CCDC151,COL9A1,ACBD5,CPS1,CLOCK,CREB5,PPP1R16B,CTNND2,BOC,RASSF2,PABPC5,DCT,RHOBTB1,SV2A,NTM,DLG2,DMD,HIPK3,KLHL5,MBNL2,TENM1,ELAVL4,EMX2,EYA1,ZIC4,TUBB4A,SCML2,CHST15,FGF13,SEC23B,IP6K2,AGAP3,MPP6,PHYHIPL,GABRA1,GBX2,MSTN,RAB30,PLCD4,GRIK3,GRM3,GRM8,AP4S1,BACH2,SHISA6,IGFBP1,IL11RA,KCND1,KCNH2,KCNMA1,LIMS1,LMO1,SYTL4,MARK1,AQP11,MITF,ADAM22,MSRA,MYT1,NDP,NF1,NOS1,NOVA1,NPTX2,OPCML,ZNF827,PDE4D,PDGFRA,PDYN,GPR85,CDK14,NLGN3,KCTD15,PLIN1,STRN3,POU3F4,LRRN3,PPP3CB,SYTL2,PTK2,PTPRO,RAB5B,RASGRF1,RASGRF2,RBBP8,DPF2,ZNF532,CYB561D1,ROBO1,RORB,KCNIP2,RTN1,SATB1,KIF21A,PPM1E,SLC8A3,TRERF1,SOX5,ZNF423,NPAS3,LMO3,SMOC1,SSTR1,LRRC4,STAC2,GSE1,ANKRD28,SYT4,SEMA4A,KLHL4,SATB2,PCDHGB7,DOCK9,NSD1,PCDHAC2,CHST8,HHIP,NR2E1,TPM2,TRPS1,MGAT5B,P2RY12,CELF4,WNK1,PMEPA1" Transcription Factor Binding Site V$MYOD_Q6 V$MYOD_Q6 1.18E-07 7.22E-05 2.29E-06 1.60E-05 74 200 "DSCAML1,SLC12A5,MTUS1,SPOP,ANK2,PKP4,DGKD,B3GALT2,NOL4,FGF17,JAZF1,USP2,ARHGEF2,PHACTR3,RIMS2,HDAC9,DCT,C2CD2L,RHOBTB1,DMPK,CDON,SHANK1,DSCAM,HEYL,ELAVL3,ELAVL4,ERBB4,ZIC4,PRKAG2,NSG2,CELF1,TBR1,NKX6-2,ARPP21,GFRA1,PPARGC1A,GK,RND1,GNAS,AP4S1,GUCY1A1,MYLK2,RBPJ,KCNH2,KCNN3,ADAM11,MID1,MDGA1,HS6ST3,NBL1,NHLH1,PAK3,STRN3,PTPA,PRKCG,PROX1,ANKHD1,RASGRF2,GTDC1,HES6,SELL,SPTB,TAB2,NKAIN2,PLCB1,SYT4,FBXW11,TJP1,NR2E1,FNDC5,KCNE5,SLC26A10,SCG2,DPF3" Transcription Factor Binding Site V$E2A_Q2 V$E2A_Q2 1.19E-07 7.32E-05 2.29E-06 1.60E-05 72 193 "SPOP,AMPD2,APBB2,DGKZ,DGKD,ATP2A2,ADGRB2,BCL7A,JAZF1,KALRN,CAMK2G,SYT6,CAST,CBLN1,USP2,ARHGEF2,SLIT2,DNAJB5,NRG2,PHACTR3,PABPC5,ARMCX2,DCT,WDR20,DMD,DSCAM,EIF4G2,ELAVL3,ELAVL4,FGF11,NSG2,TPPP3,GJB1,GK,GNAS,RAPGEF4,GRIK3,GRIN1,PSIP1,GUCY1B1,IGF1,KCNMA1,MID1,MDGA1,PLCB2,PPP2R2B,PTPA,MASP1,PSD,ANKHD1,ZNF532,KCNIP2,CPEB3,EPN2,LGI3,WDTC1,C11orf87,TAB2,NKAIN2,SEPT3,GSE1,VPS13A,CNTN2,FNDC5,KCNE5,EIF4ENIF1,USP32P2,MKRN3,SH3GLB2,SLC30A3,PRDM8,NETO2" Transcription Factor Binding Site V$CDPCR1_01 V$CDPCR1_01 1.43E-07 8.79E-05 2.54E-06 1.78E-05 47 109 "CSMD3,SLC12A5,TBC1D14,DPP10,LINC00173,NOL4,NOG,CPNE6,NRXN3,PPT2,CREM,DGKB,BRINP1,WDPCP,EEF1A2,ETV1,FGF12,FOXG1,STAG2,GART,NTNG2,INSM2,STMN2,GRIK4,IL1RAPL1,KAT7,ITGA7,KCNA1,KCND1,MAOB,MBNL1,MEIS1,MN1,NKX2-2,NOVA1,ZNF827,SERPINI1,RFX4,RPH3A,BTBD3,SON,TCF7L2,THRA,MGAT5B,CELF4,TMEM237,ST7" Transcription Factor Binding Site RYTGCNWTGGNR_UNKNOWN RYTGCNWTGGNR_UNKNOWN 1.44E-07 8.85E-05 2.54E-06 1.78E-05 41 90 "KIAA1324,TRMT9B,OGT,ANK2,DDR1,CACNB2,CAMK2A,SYT6,CALY,SHANK1,ARRDC4,KATNAL1,PTK2B,HPCAL4,POLL,PCSK1N,GRIN2D,LRRTM3,KCNN2,FXYD7,FXYD6,NNAT,NOS1,NLGN3,FXYD1,PPP3CA,MAPK10,RFX4,PNMA8A,ITSN1,PPM1E,BTBD3,SLC8A3,NCDN,FNDC9,CHST8,ITGB3BP,TIMP4,TP53BP1,ZNF24,SLC39A12" Transcription Factor Binding Site V$AP4_Q6_01 V$AP4_Q6_01 1.45E-07 8.89E-05 2.54E-06 1.78E-05 76 208 "ABR,CSMD3,SPOP,ALK,ANK1,GAS7,CADPS,CHRD,NOL4,BACH1,BCL2L2,FGF17,CDK5R2,SYT6,NEURL1,ARHGEF2,NUMBL,GPR37L1,ZNF385A,CSF1R,SPOCK2,BRINP1,DLG2,DMD,DRP2,MBNL2,SEZ6,ETV1,RASL12,EYA1,CLVS1,TUBB4A,FGF12,FGF13,SORBS1,TPPP3,GRIK3,GRIN2D,LINC01089,PSIP1,CELF3,AGBL5,HPCA,USP54,KCNN2,VWA5A,MYCN,MYH3,MYO7A,PPP3CA,PPP3CB,PRKCB,PRKCG,MASP1,PSD,SYTL2,PTH1R,RAB3A,RAB5B,RGS12,RTKN,RXRG,HES6,TRIM46,FRMPD1,MYO18A,PREX2,BTBD3,ATF7IP,SOX2,ZSWIM8,CNTN2,ADGRL3,FNDC5,EIF4ENIF1,PCBP4" Transcription Factor Binding Site TTANTCA_UNKNOWN TTANTCA_UNKNOWN 1.75E-07 1.07E-04 2.94E-06 2.06E-05 217 760 "METAP1D,SLITRK1,ADCY8,GPR158,KLHL13,PLA2G6,BCAR3,ALK,TRMT9B,CPNE5,CASK,ASCL1,ASPA,B3GALT2,NRP2,JAZF1,C5,WASF1,CA8,CABP7,CAMK2D,HIP1R,SPAG9,USP2,CBFA2T2,DGKI,DCLK1,LARGE1,MAGI1,NOG,CRLF1,NUMBL,CHN2,CLCN4,NMT2,CLTC,TJP2,HOMER3,FHL5,COL4A5,CREM,CRHBP,CREB5,ATRNL1,CTNND2,ARHGAP24,TBC1D5,DBN1,PITPNC1,DLG2,DLX1,EXOG,DMD,DNM1,HS3ST4,USP3,RCAN1,EDN1,ELAVL2,SEZ6,NCALD,RTN3,EYA1,ACSL4,EFEMP1,DLC1,FGF12,FGFR1,BAIAP2,IP6K2,AGAP3,FLT1,UFM1,ARFGAP2,NSG2,TBR1,STAG2,CHL1,GABRB1,GAD1,RAPGEF6,ARPP21,GAP43,GCNT2,MSTN,CYP46A1,GFRA1,KIRREL3,PCDH11X,GPD1,GPM6A,GPR34,STMN2,IL1RAPL1,ADAMTS6,HPSE2,SYNPO,HNMT,SHISA6,IGF1,ZIC5,DOCK7,ITIH2,CDH20,KIF5A,L1CAM,LIFR,LMO2,SMAD1,MAP2,ADAM11,MEIS2,KITLG,PPM1L,MITF,NDP,NFIX,NHLH1,NPTX2,NUMA1,GPR88,OMG,PAK3,PAX6,PCDH9,PCSK1,PDE1A,PDE4D,CDK14,SEMA5B,TMIE,KCTD15,PLCB2,PMP22,PRRX1,POLG,POU3F4,PPP2R2B,RASGEF1B,PKIA,MAPK8,MAPK9,PROX1,MASP1,SYTL2,PTPRG,PTPRO,ZCWPW1,ARID4A,CRTAC1,RFX4,PRIMA1,LGI2,ZNF532,RORB,FBXW7,KCNIP2,RTN1,SALL1,CPEB3,FBXO11,NLGN1,RPH3A,SLC8A1,SLC8A3,SLC9A5,SHANK2,CPEB4,RIMS1,SCN3B,TRERF1,SOX5,SOX10,ZNF423,SPTB,KIF1B,LMO3,C11orf87,SRPK2,MESP1,SSTR1,ERBIN,ST5,NCDN,RGL1,STAC2,SULF2,FNDC9,ANKRD28,TAC1,PJA1,ROBO3,TAF6,TCF7,PCDHB3,TEX15,ZFPM2,ZFP91,NR2E1,C5orf64,TRPS1,TSC1,TMEFF2,UBE3A,VLDLR,ZIC2,SLC30A3,WNK1,STMN4,PRDM8,GAL3ST3,SLC17A6,HRASLS,CERS6,JMJD1C,DPF3,CPNE4" Transcription Factor Binding Site CATTGTYY_V$SOX9_B1 CATTGTYY_V$SOX9_B1 1.77E-07 1.09E-04 2.94E-06 2.06E-05 99 293 "ARID1A,NDRG2,SLITRK1,KLHL13,TBC1D14,ADGRF5,TRMT9B,ANK3,B3GALT2,ADAM15,GPC2,SPAG9,CBFA2T2,CDC27,NUMBL,CFL2,CHN1,NDST3,MAP4K4,CNN3,ZNF521,CLOCK,CRMP1,PPP1R16B,GREB1,DOCK4,HDAC9,RASSF2,MAML1,G3BP2,DLG2,DLX1,DMD,DYRK1A,EDN1,ATL1,PLEKHA1,OLIG2,DLC1,OLFM1,FGFR1,FGFR3,SEMA6C,CHL1,GFRA1,GNAO1,PSIP1,CELF3,HAPLN2,HMGB1,IGF1,KCNN2,STMN1,MAOB,MBP,MDFI,MEIS1,MID1,MITF,MN1,MYL3,NASP,NEUROD2,NKX2-2,PBX1,PCSK2,GPR85,PCDH18,MAPK3,SYTL2,LAMA1,MYO18A,FBXO11,ABLIM3,SLC6A9,SEPHS1,RADIL,SOX2,SOX5,KIF1B,LMO3,FGD4,TCF4,TRIM2,TNS2,CHST8,TIAM1,TPM3,TPM4,UBE3A,OSBP2,MGAT5B,VLDLR,DPYSL5,PRDM8,PCBP4,FAM13C,KAT6A,GJC2" Transcription Factor Binding Site V$RFX1_02 V$RFX1_02 2.35E-07 1.44E-04 3.79E-06 2.66E-05 74 203 "CSMD3,CASKIN1,TRMT9B,ANK2,GAS7,ATP1A3,BAIAP3,KALRN,CAMK2A,SYT6,PPT2,RGS6,CALY,PUM1,HDAC4,SPATA2,ELMO1,DMD,ARRDC4,ATL1,ELAVL3,EML1,DMTN,NCALD,KATNAL1,TBC1D16,PTK2B,TUBB4A,HPCAL4,AGAP2,CINP,CHL1,POLL,PCSK1N,GPR17,GRIN2D,GRM1,NIM1K,ITPKA,KCNJ9,KCNJ16,MPP2,FXYD7,FXYD6,NOS1,TMIE,PLEC,FXYD1,LRRN3,CEP41,PRKCG,MAPK10,HYDIN,PSD,RFX4,ZNF532,KCNIP2,ITSN1,PPM1E,BTBD3,SLC8A3,BDP1,TSNAXIP1,KDM3A,FGD4,SYT5,ITGB3BP,ICAM5,TP53BP1,TRPS1,TUB,CRB2,SH3GLB2,SLC17A6" Transcription Factor Binding Site V$OCT1_02 V$OCT1_02 2.49E-07 1.53E-04 3.92E-06 2.75E-05 68 182 "CSMD3,DOC2A,ANK3,PPFIA2,CACNA1D,NRXN3,COL9A1,GAL3ST1,ZNF521,HDAC9,CHRDL1,DLG2,DLX1,DMD,HS3ST4,DNAH9,DPYSL2,DSCAM,TENM1,ELAVL4,ERBB4,ZIC4,FGF13,FGFR1,TBR1,GABRG2,ARPP21,GAP43,PPARGC1A,KIRREL3,GNAL,GPR17,IL1RAPL1,ZHX1,GABARAPL2,INSM1,ZNF385B,KCNN3,MAP2,MBNL1,MEIS1,NFIA,NHLH1,NPTX2,OMG,PAX6,PCSK2,PDE1A,PDE4D,PDZRN4,LRRN3,RASGEF1B,CEP41,PTPRN,CARF,PKNOX2,SEPHS1,ATF7IP,NPAS3,RGL1,TCF4,PCDHGA1,THRA,TRPS1,TSC1,ZIC1,ZIC2,PRDM8" Transcription Factor Binding Site V$AMEF2_Q6 V$AMEF2_Q6 2.83E-07 1.74E-04 4.35E-06 3.04E-05 76 211 "ASIC2,SLITRK1,MTUS1,SLC4A4,NRP2,JAZF1,USP2,ARHGEF2,CDH10,NOG,SLC24A2,CNTN1,PCYT1B,COL9A1,HS3ST5,CRHBP,CREB5,HAPLN1,SNCAIP,PPP1R16B,HDAC9,DCTN1,C2CD2L,RHOBTB1,SV2A,CHRDL1,DLG2,EDN1,MBNL2,ELAVL2,ETV1,EYA1,CACNG3,TBC1D16,FGF13,ATP5PD,FLT1,ARPP21,SALL3,MSTN,PPARGC1A,GNAO1,WIF1,HAS2,ZNF385B,ITGA7,MID1,CTNNA3,MYH6,MYO9A,NDP,PENK,ZDHHC8,PDZRN4,PRRX1,PPP2R2B,USP47,ZCWPW1,RBBP6,RFX3,RGS3,CYB561D1,RORB,RTN1,SALL1,SOX2,SOX5,SOX15,SPTAN1,TACR1,FBXW11,CLASP1,TPM2,GAL3ST3,JMJD1C,SSPN" Transcription Factor Binding Site V$FOXO4_01 V$FOXO4_01 3.04E-07 1.86E-04 4.55E-06 3.18E-05 72 197 "ASIC2,CSMD3,C1QTNF3,CADPS,LINC00173,SLC4A4,STX16,MTMR2,LDB2,CBFA2T2,CACNA2D2,CASC2,ZFYVE9,TJP2,ZNF521,SNCAIP,CSNK1G3,SLITRK5,HDAC9,PITPNC1,DMD,NYAP1,SLC12A6,ABCC5,EIF4G1,EPHB1,ETV1,EZH1,CACNG2,FGF14,FOXG1,SALL3,BRD8,NR3C1,ATOH8,KLF12,NIM1K,IL6ST,ZNF385B,LRRTM3,MBNL1,MEIS2,SESN3,MXI1,NTRK3,PALM,PDE4D,ENPP2,PFKFB3,PLCB2,EPN1,PROX1,PTH1R,PXK,SH3GL3,ABLIM3,ATF7IP,TRERF1,KDM3A,NMNAT2,ST5,ANKRD28,SATB2,PCDHB15,CRB1,HHIP,THRA,TJP1,C5orf64,TRPS1,UBE2H,VLDLR" Transcription Factor Binding Site CCCNNGGGAR_V$OLF1_01 CCCNNGGGAR_V$OLF1_01 3.21E-07 1.97E-04 4.69E-06 3.29E-05 89 259 "DPF1,TTYH1,ABR,RBM10,ARID1A,C1QTNF1,PPFIA2,ATP1A1,ATP2B3,ADGRB2,CACNA1I,DDR1,CALM1,KALRN,SLC25A14,LHX2,PCYT1B,COL11A2,AKAP12,C2CD2L,CHRDL1,DLX1,HS3ST4,DMPK,HS3ST2,CDON,ECM2,SGK2,ELAVL3,EFS,CLVS1,FGF11,FLT1,STAG2,CHL1,GCNT2,C1QL1,GNAO1,GPM6B,GRIK1,GRIK3,GRIN2D,GRM7,HPCA,ICA1,LRRTM3,KCND1,MAP4,MEIS2,GIT1,SCG3,MDGA1,NEUROD2,OPCML,ENPP2,PDZRN4,MAPKAP1,PRRX1,MAGEL2,EPB41L4B,PACSIN1,PPP3CB,RAB39A,SYTL2,PTAFR,PTHLH,ZDHHC14,RGS3,CYB561D1,SMPD3,FBXO11,SMARCE1,SNCB,SP4,NCDN,ROBO3,CNTN2,TNS2,THRA,TIAM1,NR2E1,TPM1,TST,UBTF,DPYSL5,CA10,LRP8,PRDM10,PCBP4" Transcription Factor Binding Site TGCTGAY_UNKNOWN TGCTGAY_UNKNOWN 4.01E-07 2.46E-04 5.72E-06 4.00E-05 136 440 "ASIC1,ADARB2,SLITRK1,GALNT13,AXIN2,SPOP,PCDH10,ANK3,PPFIA2,PKP4,DGKZ,PRX,MADD,ASPA,ADGRB2,NRP2,CACNA1B,CACNA1E,CAMK2A,USP2,P2RX6,CDH10,NUMBL,RAB3C,HECTD1,NECTIN3,PPP1R16B,CTNND1,ARHGAP24,SPOCK2,PABPC5,PITPNC1,ARMCX2,SHANK1,DRP2,DTNB,ELAVL2,SEZ6,ETV1,F5,CACNG3,CACNG2,DLC1,FGF13,CAMSAP1,MEX3B,SYNCRIP,AGAP3,USP16,FYN,STAG2,GABBR1,GAD2,GART,SRCAP,ARFIP1,LYVE1,NTNG2,RAB30,GPM6B,KCNA1,KCND1,KCND3,MAOB,MAP4,MEIS1,MEIS2,MITF,PTOV1,MXI1,FXYD6,SLCO1C1,NHLH1,OMG,PCDHGC3,PCSK1,CDK18,PDE1C,ENPP2,GPR85,PFKFB3,SNX10,PLEC,PCDH18,PURG,PDZRN4,TNPO2,POU3F4,PPP2R2B,PPP2R5C,GDPD2,PTPRG,PTPRN,RAB5B,RLBP1,ZNF532,FBXW7,RYR1,MAPK12,LRRTM4,GALNT10,PPM1E,FBXO11,SLITRK3,SNAP25,SNCB,MBD5,SON,LMO3,TAB2,LRRC4,NCDN,FNDC9,ANKRD28,SYT4,SYT5,TBL1X,TCF4,TRIM2,SZT2,NSD1,TEK,DICER1,ZFPM2,TPM4,ZNF384,TUBA3FP,TUB,WNT7A,WRN,KCNK12,CA10,STMN4,NAV2,PCBP4,JMJD1C" Transcription Factor Binding Site V$HNF6_Q6 V$HNF6_Q6 8.41E-07 5.16E-04 1.17E-05 8.21E-05 71 198 "CSMD3,SLITRK1,MTUS1,ADGRB3,JAZF1,SYT6,CAST,CDH10,CHN2,DGKG,BRINP1,DCTN1,CALN1,ABI1,EDN1,RCAN2,ZIC4,ATP6V1H,JPH4,MSTN,PCDH17,GNAO1,GRIK2,GRM3,IL1RAPL1,GABARAPL2,HNF4G,MAT2A,MBNL1,MEF2C,MITF,MN1,NEUROD2,NFIX,NOVA1,HCN1,OGG1,ZNF827,PDGFRA,GPR85,PIK3R1,KCTD15,PDZRN4,LRRN3,GAL3ST4,ZNF532,NEK11,SALL1,FBXO11,PREX2,SLC6A9,SLC12A2,TTC17,SRPK2,CLSTN2,POGZ,SST,SULF2,ANKRD28,NSD1,ARHGEF12,THRA,NR2C2,VLDLR,ZIC1,ZIC3,CELF4,WNK1,CA10,KCNAB1,SLC17A6" Transcription Factor Binding Site V$OCT1_03 V$OCT1_03 1.14E-06 6.97E-04 1.55E-05 1.08E-04 67 185 "PHF12,NOL4,ATP6V0A1,BCL2L2,NRP2,ARHGEF7,FOXN3,MS4A7,COL4A5,CREB5,CTNND2,RIMS2,CX3CR1,HDAC9,MED24,DLX1,DMD,RCAN1,DYRK1A,WDPCP,EMX2,RCAN2,PIPOX,EYA1,CLVS1,CACNG2,DLC1,FGF13,FOXO3,STAG2,IL1RAPL1,KLF12,BACH2,HNRNPK,ZNF385B,LIFR,LMO1,MBNL1,MEF2C,MEIS2,MID1,MITF,NAP1L2,RCOR2,NFIX,NPTX2,PDGFRA,GDAP1L1,PLEC,PPP2R2B,PTPRG,FBXW7,SALL1,FRMPD1,FBXO11,SLC6A11,SOX5,ZNF423,LMO3,FGD4,TAC3,TBL1X,TCF4,CDH22,TP53BP1,FLRT1,JPH3" Transcription Factor Binding Site GTGGGTGK_UNKNOWN GTGGGTGK_UNKNOWN 1.59E-06 9.75E-04 2.11E-05 1.48E-04 80 234 "KCNH8,ASIC2,ADD3,MTUS1,PCDH10,DOC2A,LRCH2,MAP4K3,APP,PRX,CHRD,ATP2B3,BCS1L,CACNA1A,CHRM1,CPNE6,CLTC,MAGED1,PPP1R16B,CTNND1,PHYHIP,CHRDL1,ATL1,EGR3,ELAVL2,ACSL4,PPP1R1B,FOXO3,SORBS1,GABRA1,AHCYL1,GRIA1,NR3C1,GRM3,HAS2,NXPH3,KLF12,IGF1,KCND1,KCND2,KCNH2,MAPT,SCAMP5,MITF,GIT1,CTNNA3,MYCN,RCOR2,NEUROD2,NRGN,PAK3,PCSK2,PRRX1,PPP2R2B,PPP3CA,MAPK10,PTHLH,PTPRG,ZCWPW1,ASIC4,FAM214B,SHANK2,SLC12A2,SOX10,SOX15,SP2,SP4,SPTB,EPB41L3,SIRT1,CDH22,THRA,TPM1,ZNF384,CA14,TUB,UCHL1,CELF4,SEMA3B,PCBP4" Transcription Factor Binding Site V$SOX5_01 V$SOX5_01 1.61E-06 9.91E-04 2.11E-05 1.48E-04 74 212 "ADRB2,KLHL13,SEMA6A,LRCH2,ANK2,ANK3,SPAG9,FMNL3,CBFA2T2,CASC2,COL4A5,ATRNL1,PUM1,RASSF2,RHOBTB1,G3BP2,DLG2,DLX1,ELAVL2,ELAVL4,EN2,EPHB1,ERBB4,TUBB4A,SEMA6C,STAG2,SALL3,EML4,FICD,HAPLN2,ZNF385B,LRRTM3,MARK1,MXI1,MYL3,NASP,NCAM1,NFIA,NFE2L2,NOVA1,NPTX2,PCSK2,PDZRN4,POU3F4,PPM1B,PPP2R2B,MAPK3,RFX3,SOX6,FBXO11,ZNF365,PREX2,CPEB4,TTC17,TRERF1,SOX2,SOX5,SPTAN1,LMO3,KANK1,PLCB1,ANKRD28,TCF4,SATB2,TCF12,RALYL,HHIP,C5orf64,RBFOX2,NR2C2,ZIC2,WNK1,KAT6A,CAMK1G" Transcription Factor Binding Site TGAYRTCA_V$ATF3_Q6 TGAYRTCA_V$ATF3_Q6 2.68E-06 1.65E-03 3.41E-05 2.39E-04 130 430 "ABR,SLC25A25,ADARB2,ADCY8,ADRA1B,AP2A2,PKP4,ALS2,PRX,CDK13,NOL4,CACNA1G,CA12,CALM1,CAMK2D,CH25H,SPAG9,KYAT1,CBFA2T2,SYNGR3,CFL2,CHGB,CLCN4,SULT4A1,CNN3,CREM,AKAP12,HAPLN1,RNF14,CS,SNCAIP,PHACTR3,CTNND1,KCTD8,DAPK3,SPOCK2,PITPNC1,DCTN1,PARD6A,G3BP2,HS3ST2,RCAN1,SGK2,CELSR3,EGFR,MBNL2,PLEKHA1,ING4,BSCL2,OLIG2,EPB41,RCAN2,NCALD,EFS,DNAJC27,EYA1,OLFM1,FGF12,ZMYND15,FLT1,AKAP3,TACC2,ABLIM2,STAG2,HBS1L,MYOZ2,PPARGC1A,RUNDC3A,RAB30,LOXL3,GNG3,GPM6B,ADAP1,GPR22,GRIA4,GRIN1,CELF3,ELOVL5,IGF1,SCRT2,KCNF1,KCNK1,KCNN2,ZFYVE27,ADAM11,SCAMP5,MID1,MITF,SESN3,MYO7A,MYT1,NF1,NOVA2,OGDH,PCSK1,PCSK2,PNMA3,SCHIP1,PPP2R5C,MAPK10,PTHLH,FIGN,RPRD1A,SBF1,TNFRSF19,SH3BGR,SLN,SNAP25,FAIM2,SCN3B,SPATA7,LMO3,C11orf87,SST,ST5,NCDN,FBXW11,TBL1X,TJP1,NR2E1,DAAM2,TPM3,RUSC1,UBE2H,VGF,ZNF184,SLC38A1,STMN4,SCG2,NUP214" Transcription Factor Binding Site YATTNATC_UNKNOWN YATTNATC_UNKNOWN 2.72E-06 1.67E-03 3.41E-05 2.39E-04 98 305 "TTYH1,ADD3,AXIN2,C1QTNF3,ANK2,PKP4,APP,LINC00173,RASL11B,ATP2A2,BMPR1B,CA4,CALB1,CAMK2D,ARHGAP33,CFL2,FOXN3,CHM,RAB3C,RAB33A,TJP2,QKI,CREB5,HAPLN1,SLITRK5,DOCK4,KCTD8,PITPNC1,ELMO1,DLG2,DMD,DYRK1A,MBNL2,EGR3,ELAVL2,EMX2,EYA1,DLC1,FOLR2,SORBS1,ABLIM2,ZNF512,GABRB3,GNAO1,STMN2,GRIK3,IL1RAPL1,ADAMTS6,HNMT,USP51,SHISA6,IGF1,NKD1,DOCK7,LRRTM1,KCNH2,KIF5A,MITF,MN1,CTNNA3,MXI1,NDP,NFIX,NOVA1,NPTX2,OMG,PCSK5,NALCN,TMIE,PLEC,PDZRN4,POU3F4,PPP2R2B,RASGEF1B,RFX4,KCNIP2,ABLIM3,CPEB4,SOX1,TRERF1,SOX2,SP4,KIF1B,NPAS3,SSTR1,SYT1,TAC1,ROBO3,TCF7L2,NSD1,ZIC1,ZIC2,CELF4,CA10,LRP8,ST7,CERS6,SSPN" Transcription Factor Binding Site V$NKX61_01 V$NKX61_01 3.08E-06 1.89E-03 3.79E-05 2.65E-04 66 186 "ATP2A2,ADGRB3,CDK11B,CDH10,LGI1,LARGE1,RAB3C,KMT2C,COL11A2,CLOCK,CREB5,NCOR1,CTNND1,RIMS2,BOC,SV2A,SLC12A6,KLHL5,MBNL2,TENM1,EYA1,ZIC4,FGF12,FHL1,GAD2,SALL3,PPARGC1A,NTNG2,PLCD4,LRRTM1,ITGA7,KCNJ16,KCNN3,LMO1,MAP2,MID1,SESN3,MDGA1,MYT1,NEUROD2,PCSK2,PDGFRA,CCSER2,PDZRN4,PRRX1,POU3F4,PPP3CB,PTPRD,RAB5B,RBBP8,SLC6A15,KCNIP2,PPM1E,ARX,SLITRK3,SOX5,LMO3,PLCB1,TCF4,SATB2,NSD1,ZFPM2,C5orf64,SEZ6L,WNT7A,WNK1" Transcription Factor Binding Site V$ZIC3_01 V$ZIC3_01 4.07E-06 2.50E-03 4.90E-05 3.43E-04 73 213 "MTUS1,PCDH10,OGT,PHF12,PRX,PTCH2,STX16,BCL2L2,CDK5R2,ARHGAP33,NRXN1,CLTC,CNTFR,ZNF521,PPP1R16B,CTNND1,RBM12,DMTN,EPHB1,SYNCRIP,STAG2,GABRA1,GABRA3,GABRG2,ZMYND11,GHR,GJB1,LOXL3,GNAO1,GNAS,GRIK3,GRIN2D,HAS2,HPCA,NEGR1,LRRTM3,KCND2,KCNH2,KCNK3,MYCN,RCOR2,NELL2,NHLH1,NKX2-2,PAX6,GPR85,NLGN3,MAPK10,GDPD2,PYGM,ZNF532,CYB561D1,PAQR6,SAFB,SLITRK3,DHX30,SCN3B,TRERF1,ZSWIM8,TAL1,THRA,TIMP4,ZFP91,ZNF384,CA14,UCHL1,CRB2,CA10,LRP8,PRDM8,PRDM10,SEMA3B,PCBP4" Transcription Factor Binding Site V$MMEF2_Q6 V$MMEF2_Q6 5.03E-06 3.09E-03 5.94E-05 4.16E-04 77 229 "ASIC2,ADD3,SLC12A5,BEGAIN,PRX,ASPH,ADGRB3,NRP2,USP2,CBFA2T2,DGKI,NOG,CFL2,CHN2,DNAJB5,COL11A2,HS3ST5,CPS1,CRHBP,HAPLN1,CSNK1E,PPP1R16B,RIMS2,DCTN1,RHOBTB1,SV2A,DLG2,DMD,DMPK,MBNL2,ELAVL2,ELAVL4,RTN3,EYA1,FGF13,FLT1,GPR153,TBR1,STAG2,GABRA1,SALL3,MYOZ2,KIRREL3,GRIK1,HAS2,ZNF385B,LRRTM1,ARHGAP12,ADAM11,MITF,MXI1,MYH6,NHLH1,PENK,CDK14,ZDHHC8,PRRX1,POU3F2,PPP2R2B,LRRN3,ZCWPW1,RFX3,CYB561D1,RTN1,SALL1,SOX3,SOX5,ARHGAP26,LMO3,TACR1,CLASP1,UBE3A,ADAMTS9,GAL3ST3,SSPN,FXR1,GAN" Transcription Factor Binding Site TGCCAAR_V$NF1_Q6 TGCCAAR_V$NF1_Q6 5.95E-06 3.66E-03 6.90E-05 4.83E-04 164 574 "ASIC1,NDRG2,ADARB2,DSCAML1,ADD3,AXIN2,ADRB2,C1QTNF1,C1QTNF3,SEMA6A,SPOP,BBOX1,PI16,MAP4K3,DGKD,DDO,ARRB2,STK33,B3GALT2,NRP2,BTRC,CACNA1D,CACNB2,CALM1,SPAG9,CLDN10,RGN,CBFA2T2,CDH10,DCLK1,NUMBL,CPNE6,HECTD1,ARHGEF6,CS,PHYHIP,BRINP1,DCT,B3GAT3,G3BP2,DLG2,DLG3,DLX1,DMD,HS3ST4,DTNB,WDPCP,EDN1,PLXNC1,EIF4G1,EPHA5,ERBB2,NCALD,PIPOX,MRVI1,OLFM1,AMOTL2,AGAP2,SYNCRIP,ABLIM2,PHYHIPL,GCNT2,GDF1,MSTN,ARFIP1,GFAP,GHR,GNAO1,GPD1,GPR22,RAPGEF4,MAP4K5,KLF12,BACH2,HPSE2,ZIC5,IGSF1,SCRT2,LRRTM3,ITGA7,ITIH2,KCNK3,KIT,LIFR,HECTD2,MAPT,MAT2A,AQP11,MBNL1,MEIS2,MITF,CTNNA3,MYBPC1,MYH3,MYL3,NAP1L3,NCAM1,RCOR2,NEUROD2,SLCO1C1,NFIA,NFIX,NNAT,HCN1,NTRK3,OPHN1,PDE1A,ENPP2,NLGN3,GDAP1L1,NALCN,SNX10,SMOX,PLP1,PLXNB1,PDZRN4,PMP2,MAGEL2,PPP2R2C,PPP2R5E,PROX1,APTX,SYTL2,GDPD2,MDGA2,PTHLH,PTK2,ROBO1,PAQR6,ZNF821,KIF21A,SLC6A11,NAPB,SLC15A2,CPEB4,KIF13A,WDTC1,LMO3,MESP1,NUDT10,PLCB1,SYT4,ANKRD12,TCF4,ARHGEF12,PUM2,SLC35G2,HHIP,TPM3,TRPS1,KCNE5,HIRA,EIF4ENIF1,UBE2H,FLRT1,TOM1L2,VSNL1,ZIC2,WNK1,PRDM2,STMN4,PRDM8,NAV3,PCBP4" Transcription Factor Binding Site V$E4BP4_01 V$E4BP4_01 6.45E-06 3.96E-03 7.20E-05 5.04E-04 62 175 "ADRB2,OSBPL6,OGT,PPFIA1,BSN,CALM1,USP2,DGKI,CDC42,LARGE1,RAB3C,NDST3,SLC24A2,NMT2,CREB5,RGS6,CSNK1E,SPATA2,DMD,ECM2,ELAVL4,CALCRL,EPB41,ACSL4,FGF14,FOXO3,FUT9,MPP6,GPM6A,IL1RAPL1,HRH3,GABARAPL2,NEGR1,IL6ST,MAP4,LRP1B,MPP2,NPTX1,PCSK2,PIK3R1,PTHLH,ZDHHC14,FBXW7,SH3GL2,CLSTN1,PREX2,EPN2,FAIM2,FNBP1,POGZ,RGL1,SYT11,PLCB1,CLASP1,TNS2,RBFOX2,UCHL1,ZBTB14,PMEPA1,PRDM8,JMJD1C,JPH3" Transcription Factor Binding Site V$S8_01 V$S8_01 6.45E-06 3.96E-03 7.20E-05 5.04E-04 71 208 "SLC25A25,SLC24A4,MTUS1,OGT,ANK2,ARNTL,JAZF1,LDB2,NRXN1,SLC24A2,CNN3,CS,SOCS5,CTNND1,DCT,DLX1,DMD,DSCAM,PHC2,EFNB3,SEZ6,ETV1,PIPOX,TESK2,SALL3,GAP43,GBX2,GCNT2,GRM5,HAS2,HPSE2,LRRTM1,KCNK2,MBNL1,ADAM11,MEF2C,MEIS1,MITF,MYT1,PDE3B,KCTD15,PDZRN4,PRRX1,MAPK8,SYTL2,PTH1R,SLC6A15,FIGN,RFX3,RORB,LRFN5,SCN3A,PREX2,BTBD3,SOX5,ZNF423,NPAS3,LMO3,CLSTN2,POGZ,LRRC4,SULF2,GSE1,TAC1,ZFPM2,HEY2,C5orf64,KAT6B,SEZ6L,PRDM8,JPH3" Transcription Factor Binding Site RNGTGGGC_UNKNOWN RNGTGGGC_UNKNOWN 6.79E-06 4.17E-03 7.45E-05 5.21E-04 171 604 "ASIC2,CSMD3,FMNL2,ADD3,SLC12A5,LCNL1,AK2,BEGAIN,AMPD2,PHF12,PKP4,PPFIA3,USP37,APP,PRX,B3GALT2,SYNJ1,CACNA1A,PTBP2,CAMK2A,HIP1R,CCKBR,CERS5,P2RX6,CD86,SYNGR3,NEURL1,LRRFIP1,ADGRG1,CHRM1,CHRM4,CHRNB2,DNAJB5,COL9A3,NRG2,AKAP12,MICAL2,SOCS5,RIMS4,PPP1R16B,ARMCX2,DCTN1,PARD6A,DLG2,DLG3,DMD,DMPK,OLIG1,SHANK1,DMTF1,DPYSL2,DRD1,ATL1,EFNB3,GPR61,EGR3,ELAVL4,RGS17,EMX2,SEZ6,EPHB1,ACSL4,PTK2B,DLC1,FGF11,FGF12,POLK,FOXG1,SYNCRIP,FLT1,FYN,GABBR1,CHL1,GJB1,GNAS,STMN2,ADAMTS13,NR3C1,KAT7,NXPH3,KLF12,ELOVL5,DHX35,SHISA6,ITPKB,KCNB1,KCND1,KCND3,KCNH2,KCNN3,MAN2A2,CHST6,MEIS2,MPP2,GIT1,MXI1,NCAM1,RCOR2,NKX2-2,NRCAM,NRDC,NRGN,NUCB1,ODF2,OGG1,PAK3,PBX1,PCSK2,PFKFB3,PKD1,KCTD15,PRRX1,PACSIN1,TNPO2,SH3KBP1,PPP2R2B,PPP2R2C,PPP3CB,CEP41,PRKCB,KLK6,ANKHD1,PTPRE,ZCWPW1,RBBP6,CYB561D1,FBXW7,RTKN,FAM192A,SAFB,SALL1,SH3GL3,PPM1E,BTBD3,FAM214B,KANSL3,SLC8A3,CMTR2,TRERF1,SP4,SPTAN1,SMOC1,SSTR1,EPB41L3,ST5,NCDN,TTBK2,GSE1,COBL,SEMA4A,PDLIM2,KLHL4,SATB2,TNS2,SIK3,NR2E1,TP53BP1,TUBA3FP,RUNDC3B,CA14,HIRA,VLDLR,CELF4,SH3GLB2,ADAMTS9,SEMA3B,PCBP4,FBXO36,AP3B2,SLC4A10,CPNE4" Transcription Factor Binding Site V$FOXO1_01 V$FOXO1_01 6.96E-06 4.28E-03 7.50E-05 5.25E-04 69 201 "AXIN2,C1QTNF3,BIN1,SEMA4G,CADPS,LINC00173,SYT6,SPAG9,CBFA2T2,AP4M1,FOXN3,CREM,SNCAIP,CSNK1G3,PHACTR3,SLITRK5,DLX1,DMD,USP3,ELAVL2,EML1,EPHB1,ETV1,EZH1,EFEMP1,FGF12,FGF14,NSG2,SALL3,GFRA1,GRIK3,IL1RAPL1,KLF12,NIM1K,IGSF1,ZNF385B,KCNN1,SMAD1,MITF,SESN3,NF1,NFIX,NFYA,NKX2-2,NTRK3,PALM,PLCB2,SDK2,POU3F2,POU3F4,RASGEF1B,PROX1,PTPRD,ARID4A,SEMA6D,SH3GL3,ABLIM3,PREX2,ATF7IP,SOX2,KDM3A,NMNAT2,LMO3,ANKRD28,CRB1,THRA,NR2C2,TSC1,UBE2H" Transcription Factor Binding Site V$HOXA4_Q2 V$HOXA4_Q2 7.18E-06 4.41E-03 7.60E-05 5.32E-04 73 216 "ARID1A,SLITRK1,BBOX1,ALK,DPP10,BMPR1B,ARHGEF7,CAMK2D,SPAG9,ARHGEF2,CNN3,CREB5,CS,CYBB,BOC,HDAC4,MED24,DLX1,DMD,SHANK1,WDPCP,PHC2,EFNB3,MBNL2,EIF4G2,RCAN2,ZIC4,TUBB4A,SYNCRIP,ARFGAP2,STAG2,GCK,PPARGC1A,GRIA1,IL1RAPL1,ZHX1,GABARAPL2,LRRTM3,LRRTM1,LMO1,MAP2,MEF2C,MITF,NTRK2,ZNF827,PAK3,PCDH9,PIK3R1,PDZRN4,PRRX1,RFX4,RFX5,PPM1E,KDM4D,SLC9A5,ELMO2,CPEB4,SOX5,LMO3,POGZ,SMOC1,ST5,STAC2,SYNE2,ADAMTS17,ROBO3,NSD1,DICER1,CHST8,THRA,C5orf64,ZIC1,GAL3ST3" Transcription Factor Binding Site CTTTAAR_UNKNOWN CTTTAAR_UNKNOWN 9.06E-06 5.56E-03 9.32E-05 6.52E-04 217 799 "KCNH8,NCKAP5,SLITRK1,ADD3,USP31,GPR158,PCDH10,MRTFA,TRMT9B,BIN1,DPP10,SEMA7A,PI16,PHF12,PPFIA2,EPB41L5,APLP1,PPFIA3,ARHGAP5,ATP1A1,ATP1A2,NOL4,ATP6V0A1,DOCK11,JAZF1,CA4,CACNA1A,CACNA1D,CALM1,CAST,LDB2,CDK11B,AP4M1,CFL2,FOXN3,RAB3C,NDST3,RAB33A,ZFYVE9,PPT2,FHL5,COL9A1,IGDCC3,CREB5,CS,SNCAIP,FEZ2,ATRNL1,RIMS2,SNPH,KCTD8,ARMCX2,C2CD2L,CHRDL1,DLG3,DLX1,DMD,OLIG1,RPS6KL1,CALN1,DPYSL2,DSCAM,RCAN1,ECM2,WDPCP,EDN1,MBNL2,ABI2,ELAVL2,PLEKHA1,CERCAM,ELAVL4,CALCRL,EMX2,EN2,EPB41,ENPP6,TLR7,EYA1,GMPR2,MRVI1,CACNG3,PTK2B,FOXG1,IP6K2,NBEA,SORBS1,TBR1,OGA,JPH4,SALL3,PPARGC1A,KIRREL3,NTNG2,MSL3,GPM6A,GPR22,EML4,GRIA1,PLCD4,GRIK3,GRM7,IL1RAPL1,ATOH8,HAS2,PACSIN2,HPSE2,IDH3A,CDH20,KTN1,HECTD2,MAP2,MATN3,MEF2C,MEIS1,MITF,MMP17,MPP2,GIT1,CTNNA3,NASP,NBL1,NDP,NELL2,NEUROD1,NFIX,NODAL,CNOT4,NPPA,NUCB1,OMG,OPHN1,CLDN11,PBX1,PCDH9,PDE3B,PDGFRA,PDYN,CDK14,ABCB1,NLGN3,GDAP1L1,PLCL1,PLP1,SLC25A23,PCDH18,PMP22,PRRX1,NXPH1,SH3KBP1,PPP2R2B,PRKCG,MAPK10,PROX1,PRPH,MASP1,BCAS3,PXK,PEX5,PYGM,SLC25A48,RFX4,RFX5,PRIMA1,CYB561D1,ROBO1,FBXW7,SALL1,SATB1,LRRTM4,TNFRSF19,PPM1E,FBXO11,ZNF365,SLC1A3,SEPHS1,SHANK2,ELMO2,EFHD1,EPC1,TTC17,MBD5,SON,TRERF1,SOX5,SOX15,UNC5B,KIF1B,SRPK2,NKAIN2,ERBIN,ANKRD28,TCF4,TCF7,AHCYL2,SIK3,TEK,ZFP91,TP53BP1,NR2C2,AMOT,VGF,VSNL1,KLC2,PORCN,KCNK12,ZIC2,CELF4,PMEPA1,SEMA3B,FIP1L1,RTN4,KAT6A,CAMK1G,JMJD1C,DPF3,GAN" Transcription Factor Binding Site V$MYOD_Q6_01 V$MYOD_Q6_01 9.11E-06 5.59E-03 9.32E-05 6.52E-04 67 195 "NCKAP5,AXIN2,SORCS2,SPOP,APBB1,APBB2,DGKD,BCL7A,BMP7,JAZF1,CDK5R2,CALB1,CAMK2A,SPAG9,NEURL1,CDH2,ZFYVE9,RAB26,AKAP12,ELMO1,WDR20,DMD,DSCAM,ELAVL3,ELAVL4,RCAN2,SEZ6,ZIC4,FGF11,AGAP3,TBR1,POLL,GNAS,GPR37,GRIK3,GRIN1,PSIP1,HRH3,KCNA4,KCND3,KCNH2,STMN1,GIT1,MT3,MDGA1,NHLH1,PLEC,PPARA,PPP2R2B,PRPH,PSD,KCNIP2,SELL,WDTC1,SPTAN1,CLSTN2,VPS13A,TACR1,ARHGEF12,UBTF,VGF,KCNK12,USP32P2,NDRG4,SH3GLB2,SCG2,JMJD1C" Transcription Factor Binding Site V$CART1_01 V$CART1_01 1.05E-05 6.43E-03 1.05E-04 7.38E-04 63 181 "ASIC2,ASIC1,MTUS1,KLHL13,ARRB1,NOL4,CALB2,CFL2,RCHY1,ACBD5,NECTIN3,CREB5,SLITRK5,RIMS2,CHRDL1,DLG2,RCAN1,WDPCP,HIPK3,MBNL2,EYA1,EFEMP1,FGF13,FYN,ARPP21,SALL3,GBX2,CYP46A1,GRM8,HPSE2,ADAM11,MEF2C,MEIS2,MID1,MYT1,NFIX,NOS1,NPTX2,OGG1,PAK3,PBX1,PDGFRA,GPR85,KCTD15,PDZRN4,PRRX1,CRTAC1,RFX3,SALL1,LRFN5,PPM1E,SEPHS1,SOX5,ZNF423,SPTB,LMO3,POGZ,PCDHB15,ZFPM2,ZIC3,PRDM10,NETO1,JPH3" Transcription Factor Binding Site V$NKX3A_01 V$NKX3A_01 1.12E-05 6.87E-03 1.11E-04 7.75E-04 64 185 "NCKAP5,SLC25A25,SLITRK1,ATP2A2,CDK11B,NOG,CHRM1,RAB3C,NRXN3,ZNF521,CREB5,SLITRK5,DLG2,DMD,ELAVL2,EYA1,ZIC4,EFEMP1,DLC1,TBR1,ZNF512,GPR12,GRM8,ZIC5,LRRTM1,KCNMA1,KCNN3,KIT,LMO1,MBNL1,ADAM11,MID1,MYT1,NNAT,PAX6,PCSK2,GPR85,PDZRN4,SH3KBP1,POU3F2,POU3F4,PROX1,PTH1R,PTN,SALL1,LRFN5,CASC3,ARX,SLITRK3,DHX30,KDM4D,CMTR2,SOX5,ZNF423,SPTB,LMO3,NCDN,ADAMTS17,TCF12,ZFPM2,THRA,TPM1,WNT7A,ZIC1" Transcription Factor Binding Site TGGAAA_V$NFAT_Q4_01 TGGAAA_V$NFAT_Q4_01 1.35E-05 8.29E-03 1.32E-04 9.20E-04 377 1497 "ABR,ASIC2,ACLY,EMILIN3,NCKAP5,NDRG2,ADCY2,SLITRK1,ADD3,ADORA1,GPR158,KLHL13,C1QTNF3,SEMA6A,SRPX,BCAR3,ABCD2,ARHGAP20,PCDH10,UNC79,MRTFA,TRMT9B,AMPH,OGT,SEMA7A,MAP4K3,PPFIA2,PKP4,GAS7,DGKZ,AQP4,PPP4R4,CASK,TMEFF1,ASPA,ASPH,ZBTB10,NUMB,DDX3Y,ATP1A2,ATP1B3,STX16,ATP2A2,ATP2B1,NOL4,FGF17,BSN,WASF1,BAIAP3,CACNB2,CALB1,CALM1,CAMK2G,CAST,SPAG9,MAP7,ARHGEF25,LDB2,USP2,CD86,NEURL1,CDK11B,ARHGEF2,DCLK1,ZNF445,NOG,CHN1,CNOT8,KMT2C,PPT2,CLCN3,TJP2,MAP4K4,FHL5,CNR1,ZNF521,ZNF385A,CREM,CREB5,HAPLN1,GDA,SNCAIP,ATRNL1,IPCEF1,PHACTR3,CNTNAP2,SLITRK5,GREB1,CTNND1,CTNND2,DOCK4,HDAC4,RASSF2,KIAA0586,DGKG,DBN1,PITPNC1,ELMO1,C2CD2L,SV2A,CCDC3,DLG2,DLX1,DMD,DPYSL2,RCAN1,ARRDC4,EDNRA,EFNB3,MBNL2,EIF4G1,ELAVL3,ELAVL4,CALCRL,DCTN4,RCAN2,ERBB4,MRPL37,ETV1,RASL12,EXTL2,EYA1,CLVS1,WAC,CACNG2,ZIC4,DLC1,PPP1R1B,FGF12,FGF13,FGF14,PRKAG2,ATP5PD,FOXG1,FOXF2,IP6K2,SYNCRIP,SEMA4D,FLNC,TACC2,ATP2C1,NSG2,ABLIM2,FYB1,CHL1,GABRB3,GAD1,RAPGEF6,SALL3,GAP43,STARD10,GCNT2,SRCAP,C1QL1,PPARGC1A,KIRREL3,NTNG2,HPGDS,RAB30,GLS,GNAO1,GNAS,GPR22,GPER1,EML4,STMN2,GRB10,GRIN1,NR3C1,GRM3,GRM8,GSN,IL1RAPL1,AP4S1,SOX21,PSIP1,GUCY1B1,CELF3,HAS2,KLF12,HMGCR,HNF4G,IDH3B,IGF1,ZIC5,NIM1K,IL6ST,IL11RA,LRRTM3,LRRTM1,ITGA7,KCNA1,KCNA2,CDH20,KCND3,KCNJ10,KCNMA1,KCNN2,STMN1,LIMS1,LMO2,SYTL4,HECTD2,LSAMP,MBNL1,LRP1B,MEF2C,MEIS1,KCTD6,MITF,MOBP,PTOV1,HS6ST3,MXI1,MYL3,MYO9A,FXYD6,NDP,NF1,NFIA,NFIX,NINJ2,NKX2-2,NNAT,NOS1,NRDC,HCN1,DDR2,KSR2,OPCML,OPHN1,ZNF827,PAK3,PAX6,PCDHGC3,PCDH8,PCSK5,PDE3B,PDE4B,PDE4D,PDE1B,PDGFRA,ENPP2,GPR85,SERPINI1,GPSM2,PLCL1,PLEC,EPN1,PLXNB1,PDZRN4,PMP22,STRN3,PRRX1,MBOAT7,SH3KBP1,POU3F4,PPARA,PPM1B,LRRN3,PPP2R5E,CEP41,PRKCG,MAPK4,MAPK10,ANKHD1,PTPRO,PTPRZ1,RASGRF2,ARID4A,KHDRBS2,CRTAC1,DPF2,RGS3,ZNF532,FBXW7,RTKN,KCNIP2,ZNF354C,FAM192A,SEMA6D,SCN2B,SCN3A,LRRTM4,TNFRSF19,SMPD3,IL17RB,TRIM46,SFPQ,COPZ1,SGK1,KIF21A,CPEB3,FBXO11,SLITRK3,SLA,SLC4A3,BTBD3,ZNF430,SHANK2,EFHD1,CPEB4,EPC1,SLN,SMARCE1,SNAP25,TRERF1,SOX2,SOX3,SOX5,SOX10,SOX11,NMNAT2,SPP1,LMO3,SRPK2,TAB2,POGZ,NCDN,APOM,STAC2,PHLDB1,STXBP1,FGD4,SYNE2,ADAMTS17,FNDC9,PLCB1,ANKRD28,SYT4,TAC1,TAL1,TBL1X,KLHL4,TCF4,SATB2,TCF12,DOCK9,RALYL,ARHGEF12,PCDHA6,TEX15,DICER1,TIAM1,DAAM2,TNFRSF1B,TP53BP1,RBFOX2,TPM1,TPM2,TPM3,ZNF384,TRPS1,SSBP2,TUB,UBE2H,UCHL1,VGF,VSNL1,NSD2,XPO1,PCDH20,ZIC1,ZIC2,ZNF138,CELF4,FSTL5,WNK1,SCG2,GAL3ST3,NAV3,CAB39L,ITM2C,SLC17A6,ADAMTSL3,JMJD1C,DPF3" Transcription Factor Binding Site V$MYB_Q5_01 V$MYB_Q5_01 1.48E-05 9.10E-03 1.40E-04 9.80E-04 69 205 "ASIC2,AK2,PLA2G6,SEMA7A,PPP4R4,B3GALT2,CAMK2A,CANX,SPAG9,CPNE6,ARHGEF6,CREB5,SPOCK2,G3BP2,DMD,DSCAM,PLXNC1,ELAVL4,BSCL2,EPB41,GPHN,GMPR2,FGF12,FGF13,MYOZ2,GCNT2,BRD8,PCSK1N,GNAS,GNG3,GPR22,KLF12,IL11RA,CDH20,LIG4,ARHGAP12,MAP4,NRGN,HCN1,DDR2,OCRL,ODF2,OMG,PCDH9,PDE3B,CDK14,ING3,MDGA2,FIGN,RFX3,RFX4,SEMA6D,LRFN5,HES6,RASA3,MYO18A,SLC6A9,OGDHL,RIMS1,SOX5,MPRIP,ANKRD28,TCF12,SSBP2,UBE2H,UBE3A,XPO1,KAT6A,JPH3" Transcription Factor Binding Site V$HAND1E47_01 V$HAND1E47_01 1.48E-05 9.10E-03 1.40E-04 9.80E-04 73 220 "ADCY6,SPOP,MRTFA,ANK1,PI16,CALM1,CBFA2T2,CDH10,LGI1,NOG,GPR37L1,NGEF,LY86,CREB5,PHYHIP,ELMO1,C2CD2L,SV2A,DMD,RPS6KL1,DPYSL2,EDN1,GOLGA7,EIF4G1,TENM1,ELAVL2,ELAVL4,DMTN,EYA1,ARMCX1,CLVS1,DLC1,NSG2,GPR19,EML4,GRIN2D,IL1RAPL1,CELF3,HAS2,HRH3,USP51,IL11RA,STMN1,LMO2,MBNL1,ADAM11,MEF2C,CTNNA3,MYH6,MYT1,RCOR2,PURG,PPP2R2C,MAPK3,RIT2,EMID1,LRRTM4,SELL,BTBD3,KANSL3,SLC15A2,SLN,OGDHL,SNCA,SOX5,ZSWIM8,LMO3,SSTR1,NCDN,RALYL,TMPO,VGF,WRN" Transcription Factor Binding Site AAAYWAACM_V$HFH4_01 AAAYWAACM_V$HFH4_01 1.55E-05 9.54E-03 1.45E-04 1.01E-03 70 209 "ASIC1,CSMD3,C1QTNF3,PRX,STX16,ATP2A2,FGF17,BMP7,CAST,CDK11B,ARHGEF2,REPS2,CDH10,LGI1,CHN2,NRXN3,CRY2,SNCAIP,KLHL3,DMD,EIF4G1,EPHB1,CLVS1,FGF13,EVL,NSG2,STAG2,ARPP21,GFRA1,PPARGC1A,GRIK2,GRIK3,ATOH8,KLF12,SCRG1,HSF2,NKD1,INSM1,ADAM11,MEF2C,MITF,SCG3,NCAM1,NFIX,OMG,PBX1,ENPP2,GPR85,NLGN3,NALCN,PIK3C2A,SDK2,ING3,SYTL2,NUDT11,SGK1,CPEB3,ATF7IP,SPHKAP,SOX1,SOX3,NMNAT2,EPB41L3,NKAIN2,TCF4,TCF7L2,TJP1,UBE3A,ZIC3,NAV3" Transcription Factor Binding Site V$OCT1_07 V$OCT1_07 1.61E-05 9.87E-03 1.46E-04 1.02E-03 48 129 "ADD3,ADORA2A,MTUS1,USP28,MAGEE2,ZBTB10,ATM,JAZF1,LDB2,KMT2C,RAB26,HDAC9,SCRN1,HEPH,RCAN1,ELAVL4,ETV1,CLVS1,ZIC4,TUBB4A,FGF11,SALL3,KCNN3,MBP,MID1,MYT1,NDP,NFIA,NFIX,NOS1,GPR85,TMOD2,CDK14,SEMA5B,PDZRN4,NXPH1,POU3F4,SALL1,LRFN5,ITSN1,SLA,BTBD3,CPEB4,TRERF1,SOX3,PLCB1,UBE3A,ZIC1" Transcription Factor Binding Site V$ZF5_B V$ZF5_B 1.61E-05 9.90E-03 1.46E-04 1.02E-03 67 198 "ASIC1,RBM10,SLC12A5,SEMA6A,DGKZ,BCL7A,MTMR3,NEURL1,KCNAB3,LHX2,NRXN1,COL11A2,NRG2,CLOCK,SV2B,GRIN3A,NYAP1,CDON,RASGRP1,CACNG7,PLXNC1,ELAVL3,GPHN,EFS,FGF12,FGF13,FGFR3,SYNCRIP,GABRA3,GAP43,MTHFD2,GFRA1,HTATSF1,GRIK3,ZDHHC15,SCRT2,INSM1,STMN1,MAT2A,MEIS2,MT3,CLDN11,ZNF827,PCDHGC3,NLGN3,EPB41L4B,PPP3CA,PSD,PTPRG,CRTAC1,RFX4,RPS6KA2,TRA2B,SCAF8,ABLIM3,SLC6A7,LGI3,EPC1,PLCB1,HHIP,THRA,ZFP91,NR2E1,PORCN,ZIC2,SLC26A10,NAV2" Transcription Factor Binding Site CAGGTA_V$AREB6_01 CAGGTA_V$AREB6_01 1.71E-05 1.05E-02 1.52E-04 1.06E-03 178 642 "CSMD3,NDRG3,AXIN2,ADRB2,TBC1D14,OSBPL6,PCDH10,SEMA7A,PHF12,ALS2,CASK,ARNTL,ASCL1,ALDH4A1,ATP1A3,NOL4,BMP7,BTK,CACNA1G,CACNA1D,CACNB2,CABP7,CAMK2A,CAST,CBLN1,SHISA7,LDB2,USP2,REPS2,DCLK1,CDR1,CRLF1,FOXN3,CHN2,CHRM1,NRXN3,CLCN3,NRXN2,TJP2,DNAJB5,MAP4K4,CREB5,PHACTR3,GREB1,HDAC4,TBC1D5,TOMM20,DBI,DCTN1,HEPH,DLG2,DMD,RPS6KL1,DTNB,WDPCP,EGR3,EIF4G1,EIF5,CERCAM,ELAVL4,BSCL2,EMX2,EPB41L1,SEZ6,ENPP6,GMPR2,PTK2B,ZIC4,EFEMP1,FGF11,FGF13,FOXG1,NBEA,DACH2,STAG2,GABRA1,CHL1,GAP43,MSTN,NTNG2,GNG3,GPM6A,GPR22,GRM2,HAS2,HPSE2,AGBL5,TLX1,USP51,SHISA6,IGF1,DISP2,LRRTM3,ITPKB,KCNA1,KCND3,KCNK1,PACRG,MBNL1,MDFI,KCTD6,MOV10,MSI1,MYH7,MIR4697HG,NCAM1,NDP,NELL2,NEUROD1,NFIA,NFIX,NRGN,NUMA1,ZNF827,PBX1,PDE4B,PDE4D,PDGFRA,GPR85,ZDHHC8,PLXNB3,PURG,SH3KBP1,PPM1B,PPP2R2B,PRKACB,PRKCZ,PROX1,PSD,GDPD2,PTHLH,PTN,OXR1,ARID4A,KHDRBS2,MYH14,LRFN5,TNFRSF19,ABLIM3,PREX2,SLC8A3,SPHKAP,TET1,MBD5,KIF13A,SOX3,SOX5,ZSWIM8,NPAS3,LMO3,SRPK2,ERBIN,ST5,PLCB1,SYT5,TACC1,TACR1,FBXW11,TCF12,DOCK9,DICER1,ITGB3BP,RBFOX2,TUBA3FP,TRPS1,KCNE5,UCHL1,VSNL1,WRN,PORCN,SF1,ZIC1,NDRG4,CELF4,SLC30A3,SLC38A1,KCNAB1,SLC4A10" Transcription Factor Binding Site V$CACCCBINDINGFACTOR_Q6 V$CACCCBINDINGFACTOR_Q6 1.77E-05 1.09E-02 1.53E-04 1.07E-03 73 221 "KCNH8,ADCY5,SLC12A5,PLA2G6,PHF12,CALM1,SPAG9,ENTPD2,CDC27,KCNAB3,LGI1,CRLF1,CHRM1,CNTFR,CREM,RGS6,BOC,DCTN1,G3BP2,DLX1,DYRK1A,EFNA3,PPP1R1B,FGF11,FOXF2,FLNC,SORBS1,STAG2,JPH4,CPLX1,GFAP,PCDH17,RAB30,MSL3,GNAO1,GRM3,KCND1,MAPT,MEIS1,GIT1,RCOR2,NINJ2,KCNK10,SLC25A23,PLTP,PMP22,MAGEL2,ZNF532,RTKN,CNKSR2,SLC6A9,SOX15,SP4,RAP1GAP2,LMO3,CAMTA2,EPB41L3,PHLDB1,GSE1,TBL1X,SZT2,ZNF384,PORCN,XPO1,LGI4,CELF4,SH3GLB2,CA10,RGMA,STMN4,SEMA3B,PCBP4,ADAMTSL3" Transcription Factor Binding Site SMTTTTGT_UNKNOWN SMTTTTGT_UNKNOWN 1.77E-05 1.09E-02 1.53E-04 1.07E-03 103 337 "ACLY,CLK4,MTUS1,PHF12,APP,DDX3Y,BTK,CAMK2G,KYAT1,USP2,FOXN3,CHN1,RAB33A,NRXN1,QKI,CNN3,PCYT1B,MAGED1,CTNND2,DMD,HS3ST4,DMPK,EDN3,RBM12,EIF4G2,ELAVL4,EPB41L1,ETV1,CACNG3,IP6K2,ZNF512,GABRA2,GATM,KIRREL3,GLYR1,GNAO1,GPM6A,GPR12,KLF12,BACH2,HMGB1,ATCAY,IGF1,IL11RA,KCNN3,STMN1,LMO1,SMAD1,MBNL1,MEIS2,MID1,MOG,SCG3,NDP,NEUROD1,NF1,NFIX,NTRK2,OMG,KCNK10,PCDH8,PDE4D,ENPP2,GPR85,NLGN3,KCTD15,EPN1,PPP2R2B,PROX1,ARID4A,ATP8B4,SAFB,SMPD3,SFPQ,TRA2B,CNKSR2,EPN2,CPEB4,EPC1,CXXC4,TRERF1,SOX3,SOX5,NMNAT2,KIF1B,LMO3,SRPK2,TAB2,LRRC4,SS18,GSE1,KLHL4,TCF4,SATB2,TCF7,CLASP1,TIAM1,CBX5,ZBTB14,DPYSL5,SLC30A3,SLC38A1,DPF3" Transcription Factor Binding Site V$AREB6_02 V$AREB6_02 2.33E-05 1.43E-02 1.99E-04 1.39E-03 67 200 "AXIN2,GPR158,USP37,NOL4,NRP2,DDR1,MAP7,USP2,CHRM1,NRXN3,DNAJB5,COL11A2,DOCK4,DGKG,ARMCX2,DCTN1,DLG2,DMD,DMPK,NYAP1,SLC12A6,DRP2,WDPCP,EDN1,ERBB4,IP6K2,SYT3,NBEA,GABRA3,GJB1,GRIK3,GRIK4,GUCY1B1,HRH3,HPSE2,IGF1,LMO2,ADAM11,MYL3,NOVA1,OMG,PIK3R1,ING3,POU3F4,PTPA,MAPK10,PROX1,PRPH,ANKHD1,RAB5B,KHDRBS2,LGI2,RTN1,SH3GL2,MYO18A,EPN2,SLC6A7,SLC6A9,RIMS1,KIF13A,SOX10,TAB2,RBFOX2,WBP2,USP1,VGF,RGMA" Transcription Factor Binding Site GTTGNYNNRGNAAC_UNKNOWN GTTGNYNNRGNAAC_UNKNOWN 2.47E-05 1.52E-02 2.08E-04 1.46E-03 32 76 "TRMT9B,KALRN,CAMK2A,PPT2,CALY,PUM1,SPATA2,ELMO1,RHOBTB1,ELAVL4,DMTN,NCALD,TUBB4A,CINP,GRM1,LRRC25,KCNJ9,MPP2,FXYD7,FXYD6,PLEC,MAPK10,HYDIN,RFX4,KCNIP2,BTBD3,SPTB,SYT5,RALYL,TP53BP1,SH3GLB2,LMAN2L" Transcription Factor Binding Site V$P53_02 V$P53_02 2.55E-05 1.56E-02 2.11E-04 1.48E-03 69 208 "ASIC2,DSCAML1,SLITRK1,SYT13,SEMA7A,DGKZ,TMEFF1,ADGRB1,CACNA1E,DDR1,CACNB2,HIP1R,CHRM1,NRXN3,TJP2,DNAJB5,CNR1,AKAP6,WHRN,CTNND2,PITPNC1,RHOBTB1,DMD,SLC12A6,ARRDC4,ABCC5,EGFR,MBNL2,EIF4G2,BSCL2,EPB41L1,ETV1,CACNG2,FOXG1,GAD1,GCNT2,GNG3,GPD2,MAP4,MBNL1,MEIS2,MITF,HS6ST3,MYL3,NDP,NTRK3,ENPP2,PRRX1,MAGEL2,NXPH1,PTPA,PTH1R,PTPRG,ASIC4,SLC1A3,PREX2,DHX30,CXXC4,TRERF1,SOX5,KDM4C,ST5,PLCB1,SYT4,FLRT1,SH3GLB2,DNALI1,PRDM8,PAK5" Transcription Factor Binding Site V$ZIC1_01 V$ZIC1_01 2.75E-05 1.69E-02 2.25E-04 1.58E-03 71 216 "FMNL2,MTUS1,PHF12,PTCH2,NOL4,CBLN1,LGI1,DNAJB5,MAGED1,CTNND1,CTNND2,DCTN1,DMTF1,DRD1,ATL1,RBM12,EIF4G1,CERCAM,ERBB4,CACNG3,ACSL4,FCGR3A,USP21,GABRG2,ZMYND11,GHR,GJB1,GNAO1,GRIN2D,NXPH3,KLF12,HPCA,USP51,NEGR1,SHISA6,KCNA1,KCND1,KCND2,KCNH2,MBNL1,GIT1,CTNNA3,RCOR2,NELL2,NFYA,NKX2-2,KCNK10,CDK18,NLGN3,PMP22,PACSIN1,DEF8,CYB561D1,FAM192A,SALL1,CPEB3,DHX30,KANSL3,TRERF1,SZT2,PCDHGA2,TPM2,ZNF384,CA14,CRB2,CA10,LRP8,PRDM10,LMAN2L,SEMA3B,PCBP4" Transcription Factor Binding Site V$FOXJ2_02 V$FOXJ2_02 2.91E-05 1.79E-02 2.35E-04 1.65E-03 64 190 "CSMD3,ARNTL,ADAM23,ADGRB3,SYT6,CAST,USP2,CDH10,NOG,NRXN1,PCYT1B,IFFO1,NECTIN3,FEZ1,ATRNL1,PHACTR3,HDAC9,C2CD2L,DMD,EDN1,EFEMP1,FGF13,JPH4,ARPP21,GHR,PPARGC1A,KIRREL3,GPM6B,ATF7,HAS2,HPSE2,LRRTM3,CDH20,LIFR,MAP2,LRP1B,MXI1,NFIA,NFIX,NPTX2,OLR1,PAX6,PBX1,PDE4B,PDE4D,CDK14,POLG,POU3F4,PPM1B,PTHLH,PTPRO,RAB5B,RORB,SATB1,SLCO1A2,TRERF1,SOX2,ZNF423,LMO3,TCF4,SATB2,TRIM2,TTC3,MRPL47" Transcription Factor Binding Site V$PAX2_02 V$PAX2_02 3.47E-05 2.13E-02 2.77E-04 1.94E-03 68 206 "ASIC2,CSMD3,ADCY8,CADPS,SYT6,CACNA2D2,CFL2,AKAP7,PHACTR3,CTNND1,KIAA0586,TOMM20,KLHL3,DMD,NYAP1,EGFR,GOLGA7,EIF4G1,EIF5,ELAVL4,EPHB1,PTK2B,ZIC4,IP6K2,EVL,FLNC,MPP6,DNER,STARD3,STMN2,GRIK3,IGF1,LRRTM1,KCNJ10,LSAMP,PACRG,MEIS2,MN1,NFYA,NTRK2,KCNK10,PFKFB3,SERPINI1,PLEC,PMP22,ING3,POU3F2,PPP2R2B,PPP2R5C,PPP3CA,PTH1R,RTN1,SEMA6D,LRRTM4,ATF7IP,SOX10,LMO3,EPB41L3,TCF4,TCF7L2,TRIM2,TCF12,ZFPM2,CHST8,CRB1,XPO1,ZNF184,DPF3" Transcription Factor Binding Site V$CHX10_01 V$CHX10_01 3.66E-05 2.25E-02 2.88E-04 2.01E-03 65 195 "ASIC1,SLITRK1,ADD3,MTUS1,GPR158,OGT,CASK,BACH1,LDB2,SLC24A2,CNN3,CS,MED24,DLG2,DLX1,DMD,RCAN1,WDPCP,ETV1,ZIC4,TUBB4A,PPP1R1B,FOXF2,AGAP3,SEMA6C,FYN,GAP43,MSTN,GNAO1,LPAR4,GRM5,LRRTM1,CDH20,KCNK2,KCNMA1,LMO1,MAP4,MITF,PAX6,PCDH9,SEMA5B,PCDH18,PDZRN4,PRRX1,PTPRG,FIGN,RGS12,LRFN5,PPM1E,BTBD3,ELMO2,ZNF423,LMO3,POGZ,SYNE2,ADAMTS17,ROBO3,CHST8,THRA,DAAM2,KAT6B,SEZ6L,VLDLR,VSNL1,ZIC1" Transcription Factor Binding Site V$HFH4_01 V$HFH4_01 3.70E-05 2.27E-02 2.88E-04 2.01E-03 58 169 "ASIC2,PPFIA2,ARRB2,ATP2A2,ADGRB3,CACNA1D,CHN2,MAP4K4,CREB5,DMD,EIF4G1,ELAVL2,ETV1,FGF14,IP6K2,TPPP3,GFRA1,PCDH17,KIRREL3,MSL3,GRM3,ATOH8,IGFBP1,ZIC5,MEF2C,MITF,SCG3,MIR4697HG,NEUROD2,NFIA,NOVA1,PDGFRA,PIK3C2A,KCTD15,PDZRN4,SCHIP1,PRKACB,SGK1,FRMPD1,FBXO11,CPEB4,ZNF423,NPAS3,LMO3,POGZ,NCDN,SYT4,CHST8,C5orf64,TNR,UBE2H,UBE3A,TOM1L2,ZIC3,CELF4,PHTF2,FBXO36,RNF146" Transcription Factor Binding Site V$SOX9_B1 V$SOX9_B1 4.19E-05 2.57E-02 3.21E-04 2.25E-03 64 192 "ADRB2,KLHL13,CASK,TMEFF1,CADPS,BSN,CBFA2T2,CASC2,SLIT2,MAP4K4,SEC24C,PPP1R16B,PUM1,DOCK4,HDAC9,MAML1,RHOBTB1,G3BP2,DLX1,DMD,CDON,DPYSL2,ELAVL2,ELAVL4,ETV1,ZIC4,DLC1,OLFM1,FGFR1,SEMA6C,CHL1,GNAO1,CELF3,HMGB1,KCNN2,MAOB,MBP,MEIS1,MYT1,NASP,NCAM1,NDP,NEUROD2,NFIX,PBX1,PPP2R2B,SYTL2,RGS3,MYO18A,SEPHS1,SOX2,SOX5,SYT4,TAL1,TEK,RBFOX2,UBE3A,VLDLR,ZIC1,ZIC2,DPYSL5,RTN4,KAT6A,GJC2" Transcription Factor Binding Site V$AP3_Q6 V$AP3_Q6 4.90E-05 3.01E-02 3.67E-04 2.57E-03 68 208 "NCKAP5,ADCY8,SEMA6A,CASK,ADGRB3,BCL2L2,FGF17,PRMT9,NRXN3,NMT2,MAP4K4,WHRN,HAPLN1,RGS6,CTNND1,DMD,EDNRA,EIF4G1,TENM1,ELAVL2,ERBB4,ETV1,CACNG3,CACNG2,TESK2,FGF13,MPP6,GAD1,RND1,RAPGEF4,IL1RAPL1,LMO1,ARHGAP12,SMAD1,MBNL1,MEIS2,PPM1L,MSR1,MYBPC1,MYH6,RCOR2,NTRK2,NTRK3,PCDH8,PCDH9,PDE3B,CDK14,SMOX,POU3F4,MASP1,DPF2,TRIM46,PPM1E,RADIL,CXXC4,TACR1,TAL1,PCDHGB2,NSD1,PCDHA6,ZFPM2,ICAM5,C5orf64,TRPS1,TMEFF2,PRDM2,JMJD1C,GAN" Transcription Factor Binding Site V$RSRFC4_01 V$RSRFC4_01 4.90E-05 3.01E-02 3.67E-04 2.57E-03 68 208 "NDRG2,ADCY2,ADAM23,ADGRB3,DIRAS1,CAPN3,USP2,DGKI,CFL2,NRXN3,CNTN1,HAPLN1,SIPA1L1,CTNND2,HDAC9,ARHGAP32,ELMO1,SV2A,DLG2,DMD,SHANK1,DTNB,EEF1A2,MBNL2,ELAVL4,EXTL1,EYA1,FGF12,GPR153,STAG2,MYOZ2,GCK,PCDH11X,HAS2,ZNF385B,ITGA7,KCNN1,KTN1,TTYH2,ADAM11,MEF2C,MYH3,MYL3,NDP,PCDH9,PDGFRA,RETREG1,RASGEF1B,PTPRO,RASGRF1,RGS3,LRRTM4,ITSN1,SLC8A3,SLC9A5,CPEB4,SOX5,ARHGAP26,FBXW11,SIK3,ZFPM2,ITGB3BP,TRPS1,CELF4,SH3GLB2,PMEPA1,GAL3ST3,HRASLS" Transcription Factor Binding Site WTGAAAT_UNKNOWN WTGAAAT_UNKNOWN 5.56E-05 3.41E-02 4.11E-04 2.88E-03 140 496 "NCKAP5,CSMD3,SPARCL1,PCDH10,OGT,PKP4,APC,ASPA,ZBTB10,B3GALT2,MTMR3,JAZF1,C5,LDB2,FMNL3,USP2,DCLK1,SYNPR,RAB33A,CPS1,CREM,HAPLN1,SNCAIP,SLITRK5,ST18,HDAC9,SNPH,TOMM20,SPOCK2,RHOBTB1,DLG2,DMD,RCAN1,ARRDC4,DYRK1A,KLHL5,TENM1,ELAVL2,ELAVL4,TUBD1,NCALD,PIPOX,GMPR2,ZIC4,FGF11,FGF13,FOXG1,NBEA,SORBS1,FYN,GABRB1,ARPP21,NEK6,MTHFD2,DNER,HTATSF1,GPD1,GPM6A,GPM6B,GPR22,GPER1,STMN2,GRM8,PSIP1,SHISA6,IGF1,IL6ST,INPP1,ZNF385B,STMN1,ADAM11,SHC3,MEF2C,MID1,MITF,MN1,GIT1,MYT1,NEUROD2,NFE2L2,NHLH1,NPTX2,OCRL,GPR88,OGG1,OMG,OPCML,P2RY1,KCNK10,SNTG1,PAX6,PCDHGC3,PCSK2,PLCL1,PURG,POU3F4,PPM1B,PPP2R5E,PRKAB2,SYTL2,PTHLH,PTK2,PTPRD,RFX3,RGS12,ROBO1,RORB,FBXW7,LRRTM4,SCN7A,SCN8A,TNFRSF19,SOX6,ARX,SLC1A3,BTBD3,SEPHS1,SLC8A3,MBD5,TRERF1,SOX2,SOX5,SPATA7,ZNF423,SPTAN1,LMO3,SRPK2,ANKRD28,TCEA1,TCF4,TLL2,NR2E1,EIF4ENIF1,P2RY12,ZIC1,LRP8,NAV3,KAT6A,SSPN,SLC4A10" Transcription Factor Binding Site V$EFC_Q6 V$EFC_Q6 6.34E-05 3.89E-02 4.63E-04 3.24E-03 71 221 "ARID1A,KIAA1324,B3GALT2,BCL2L2,AP1M1,BTRC,CACNA1D,CAMK2A,SYT6,CARS,LDB2,PPT2,PCYT1B,WHRN,MAGED1,TBPL1,SNPH,C2CD2L,GRIN3A,DMD,DNAH9,SHANK1,EFNB3,ABI2,ELAVL4,EN2,EYA1,TBC1D16,PCDH17,GPR22,GRIK5,PACSIN2,KCNA1,KCNA2,KCNN3,MEIS2,MITF,BLOC1S2,FXYD6,NEUROD2,NOS1,NRGN,PAX6,PDE1A,NLGN3,SEMA5B,PDZRN4,PRRX1,PPP3CB,CEP41,PSD,GDPD2,RFX4,ACER3,BTBD3,DHX30,SOX2,KDM3A,NPAS3,LMO3,RGL1,ROBO3,TNS2,THRA,TP53BP1,CDK20,FLRT1,DPYSL5,STMN4,SLC17A6,SLC39A12" Transcription Factor Binding Site V$COMP1_01 V$COMP1_01 7.96E-05 4.89E-02 5.75E-04 4.02E-03 37 97 "NUMB,LGI1,RAB3C,COL4A5,CREB5,CTNND2,DLX1,TOM1,MBNL2,ELAVL2,ERBB4,EYA1,CACNG3,ZIC4,NSG2,SALL3,HMGB1,IGF1,LMO1,MBNL1,MEIS2,MITF,MPP2,NCAM1,PDE1B,KCTD15,MAPK9,PROX1,SALL1,SLC1A3,TCF7L2,TCF12,NR2E1,TSC1,ZIC1,PRDM8,NAV3" Transcription Factor Binding Site TGACCTTG_V$SF1_Q6 TGACCTTG_V$SF1_Q6 8.69E-05 5.33E-02 6.20E-04 4.34E-03 65 200 "SLITRK1,FZD9,AK2,AMPD3,SEMA7A,APP,MADD,CACNB2,DIRAS1,CAMK2G,CHGA,NRXN2,COX4I1,CS,PHACTR3,PPP1R16B,SNPH,KIAA0586,SV2A,NYAP1,EEF1A2,ELAVL3,RCAN2,KCNMB2,TUBB4A,ARFGAP2,TPPP3,GABRA3,DNER,KIRREL3,NTNG2,GK,LINC01089,IDH3A,KCNK1,KIF5A,MEF2C,MYL3,NNAT,NPTX2,HCN1,SNTG1,PPP3CC,MASP1,STK32A,RAB3A,RGS7,LRFN5,SH3GL2,RPH3A,SLC6A8,OGDHL,NCDN,STAC2,ANKRD28,SLC37A2,ASTN2,CNTN2,SIK3,FNDC5,UCHL1,TBC1D15,VSNL1,SLC30A3,MRPL47" Transcription Factor Binding Site V$SMAD3_Q6 V$SMAD3_Q6 9.62E-05 5.90E-02 6.79E-04 4.75E-03 63 193 "ACTN2,ARID1A,APBB2,RASL11B,ALDH4A1,STX16,B3GALT2,CDK5R2,CACNB2,CHRM1,CPNE6,NRXN3,CLTC,CNTFR,COL11A2,PABPC5,DMPK,HS3ST2,SHANK1,EDN1,EPB41,EYA1,FGF11,FGF14,DCTN2,GRIN2D,CELF3,HAPLN2,HMGB1,SCRG1,SYNPO,TLX1,MAP2,MEIS1,MN1,GIT1,MYT1,NNAT,NTRK3,ZDHHC22,PAK3,PDE4D,KCTD15,POU3F4,PPP3CB,RFX4,RFX5,KIRREL1,EMID1,IL17RB,BTBD3,SMTN,SLC6A9,RIMS1,KDM3A,C11orf87,ST5,PDLIM2,DOCK9,TIMP4,RUSC1,JMJD1C,FXR1" Transcription Factor Binding Site V$BRN2_01 V$BRN2_01 9.94E-05 6.10E-02 6.93E-04 4.85E-03 64 197 "ASIC2,SLITRK1,C5,NOG,CHN2,CASC2,NDST3,NRXN3,CNN3,HS3ST5,CLOCK,CREB5,CS,RGS6,PPP1R16B,CTNND2,ELMO1,DLX1,DMD,EDNRA,MBNL2,TENM1,KCNMB2,EXTL2,EYA1,PPP1R1B,FGF13,FGF14,FGFR3,FOXG1,IP6K2,TACC2,SALL3,GNAO1,GPM6A,STMN2,KLF12,ZNF385B,MBNL1,ADAM11,MMP16,MYT1,NCAM2,NFIA,ANLN,PLCB2,PLEC,PCDH18,PDZRN4,PPM1B,PTHLH,PTPRG,PTPRO,RPE,RPE65,SALL1,SNAP25,SOX3,TAC3,AGTPBP1,TCF4,ARHGEF12,ITGB3BP,NR2E1" Transcription Factor Binding Site V$POU1F1_Q6 V$POU1F1_Q6 1.10E-04 6.76E-02 7.59E-04 5.31E-03 62 190 "SLITRK1,BCAR3,ANK3,PKP4,APBB1,CACNA1D,CREB5,ATRNL1,HDAC9,KCTD8,DLX1,DMD,DUSP9,SUGP2,ELAVL4,EN2,RTN3,CACNG2,ZIC4,FGF12,TBR1,SALL3,GAP43,GBX2,CYP46A1,STMN2,ZHX1,ZIC5,DOCK7,SMAD1,MAP2,MEIS2,SESN3,STK32C,MYBPC1,NHLH1,GPR88,PCSK5,PDE2A,TMIE,PDZRN4,MAPK9,PTHLH,PTPRD,ZCWPW1,PRIMA1,RORB,FBXW7,SEPHS1,ZNF423,SPTB,LMO3,STAC2,SLC37A2,DICER1,ZNF384,TRPS1,VGF,ZIC1,ZIC2,PRDM8,RTN4" Transcription Factor Binding Site V$NKX22_01 V$NKX22_01 1.15E-04 7.07E-02 7.84E-04 5.49E-03 51 149 "TTYH1,PITPNM2,ADGRB3,NRP2,CDK11B,CHRM1,ZFYVE9,ARMCX2,DLG2,DMD,ELAVL2,EPB41,COQ7,RRAGB,CLVS1,DLC1,TBR1,STAG2,SALL3,PCDH17,HPSE2,LRRTM1,CTNNA3,MYL3,NDP,NFIA,NFIX,NKX2-2,PDYN,PIK3R1,PDZRN4,SCHIP1,SH3KBP1,SYTL2,RGS3,RIT2,FBXW7,ASIC4,PPM1E,KDM4D,CPEB4,KIF13A,ZNF423,SRPK2,GSE1,SYT4,NSD1,THRA,TIAM1,WNT7A,JMJD1C" Transcription Factor Binding Site V$CREBP1_01 V$CREBP1_01 1.16E-04 7.13E-02 7.84E-04 5.49E-03 48 138 "ADRB2,OSBPL6,BSN,CALM1,SYT6,USP2,DGKI,CDC42,LARGE1,NDST3,ZFYVE9,CREB5,RGS6,CSNK1E,DMD,MBNL2,ELAVL4,EPB41,EYA1,FGF14,IP6K2,MPP6,GPM6A,IL1RAPL1,HRH3,GABARAPL2,NEGR1,LRRTM3,KCNC1,MPP2,NPTX2,PCSK2,SERPINE2,PTHLH,CRTAC1,FBXW7,CLSTN1,PREX2,EPN2,FNBP1,POGZ,SYT11,CLASP1,TNS2,ZBTB14,PMEPA1,PRDM8,JMJD1C" Transcription Factor Binding Site V$RP58_01 V$RP58_01 1.26E-04 7.73E-02 8.31E-04 5.81E-03 61 187 "ABR,ASIC2,ASIC1,C1QTNF1,ANK2,GAS7,PTCH2,ATP2A2,B3GALT2,ADGRB3,CACNA1G,CACNB2,CABP7,CALM1,FMNL3,CASC2,ARHGAP22,MAGED1,TBPL1,RIMS2,DAPK1,DLG3,DMD,MBNL2,TLR7,EYA1,SORBS1,GRIN2D,NR3C1,ATOH8,NXPH3,IGF1,LRRTM3,PACRG,MYL3,RCOR2,NKX2-2,NRGN,NTRK2,GPSM2,POU3F4,PPM1B,SEMA6D,SCN2B,KIF21A,ARX,ABLIM3,BTBD3,DHX30,SPTB,LMO3,PHLDB1,SEPT3,TAC1,ANKRD12,CNTN2,TCF12,UBTF,SH3GLB2,CA10,ADAMTS10" Transcription Factor Binding Site V$MEIS1_01 V$MEIS1_01 1.26E-04 7.73E-02 8.31E-04 5.81E-03 61 187 "SLC25A25,ADCY8,ANK2,LINC00173,B3GALT2,NOL4,SPAG9,KCNAB3,CLTC,DNAJB5,CREB5,RGS6,SPOCK2,HEPH,ARRDC4,ATL1,ELAVL4,EPB41,GPHN,NCALD,ETV1,EYA1,FGF12,FGF13,SORBS1,ARFGAP2,KIRREL3,GNAO1,GRIK3,PSIP1,MYLK2,MAPT,MYT1,NCAM1,NDP,NEUROD2,NPPA,PLCD1,PDZRN4,PPP2R2B,PPP3CA,PSMA6,PBRM1,FBXW7,FAM192A,HES6,TNFRSF19,SMPD3,SMOC1,SS18,PHLDB1,SEMA4A,TCF7L2,SIRT1,THRA,TIAM1,TIMP4,PITPNB,ZIC3,PCBP4,DPF3" Transcription Factor Binding Site V$CP2_01 V$CP2_01 1.27E-04 7.81E-02 8.31E-04 5.81E-03 67 210 "IGDCC4,NOL4,CDK5R2,DDR1,SYT6,SHISA7,CDH2,TJP2,CABP1,COL11A2,ACBD5,CRMP1,SLITRK5,HDAC9,SPOCK2,DCTN1,DMTF1,ELAVL2,RASGRP2,MEX3B,STAG2,GLYR1,RAB30,GNAS,GPD1,GRM7,IL1RAPL1,HPSE2,KCNN2,KIF5A,MDFI,PTOV1,RCOR2,NNAT,PAX6,PDE2A,KCTD15,PLEC,SMOX,SLC25A23,PMP22,MAPKAP1,PPP2R2B,MAPK3,CRTAC1,RGS3,ZNF532,RTN1,SALL1,SATB1,SLC8A3,EPC1,SOX10,CLSTN2,NCDN,STX1A,FGD4,SEMA4A,TCF7L2,DOCK9,TNS2,HIF3A,CA14,USP1,SF1,ZIC2,RGMA" Transcription Factor Binding Site ACCTGTTG_UNKNOWN ACCTGTTG_UNKNOWN 1.31E-04 8.03E-02 8.46E-04 5.92E-03 44 124 "ABR,MTUS1,DOC2A,FGF17,HAP1,NEURL1,AP4M1,RIMS4,PHYHIP,WDPCP,ZIC4,FOXO3,GALNT15,RAPGEF6,GALR1,GAP43,EML4,NR3C1,SOX21,HRH3,ELOVL5,GABARAPL2,KCND2,KCNQ3,MMP16,OCRL,GPR85,PRRX1,LRRN3,RASGEF1B,NUDT11,HUNK,RYR1,EPN2,SORCS3,RIMS1,SNCA,KIF13A,SOX10,NUDT10,TJP1,UCHL1,PCBP4,JPH3" Transcription Factor Binding Site RTTTNNNYTGGM_UNKNOWN RTTTNNNYTGGM_UNKNOWN 1.41E-04 8.68E-02 9.04E-04 6.33E-03 45 128 "ASIC2,OGT,BACH1,SPAG9,REPS2,CFL2,PCYT1B,CREB5,HAPLN1,DDX46,DMD,RCAN1,EGFR,ETV1,EYA1,ZIC4,PPP1R1B,GABRG2,MSTN,GRIA1,HAS2,KCTD6,MITF,NDP,NOVA1,SLC11A2,NTRK2,ODF2,GPR85,PPP2R5E,PTPRG,RFX3,RGS3,FBXO11,SLC6A9,ZNF423,ANKRD28,PUM2,TRPS1,ZIC1,ZIC2,CELF4,NAV3,CAB39L,DPF3" Transcription Factor Binding Site V$AP2_Q3 V$AP2_Q3 1.45E-04 8.93E-02 9.20E-04 6.44E-03 66 207 "ASIC2,SPOP,GAS7,APLP1,ADAM23,CDK5R1,CACNA1G,CHN2,LHX2,HECTD1,COL11A2,ZNF385A,CLOCK,C1QL2,PHACTR3,SLITRK5,PITPNC1,CNNM1,PLXNC1,EIF4G2,EMX2,EPHB1,CACNG2,MEX3B,FOXO3,OGA,STAG2,GABRA4,GRIK3,NR3C1,GRM3,KAT7,KCNA1,KCNA6,KCND1,KCNN2,MAPT,MAT2A,MOV10,MSI1,MYCN,NLGN3,SPATA6,RAP1GDS1,CRTAC1,PBRM1,ROM1,SALL1,PPM1E,SLC4A3,SLC12A4,EPC1,RIMS1,WDTC1,SOX2,CAMTA2,TCF7,HEY1,HIRA,UBTF,PORCN,SF1,ZIC1,ZNF70,SLC30A3,RGMA" Transcription Factor Binding Site V$GATA2_01 V$GATA2_01 1.48E-04 9.06E-02 9.23E-04 6.46E-03 34 89 "ACTN1,SPOP,NEURL1,REPS2,CDC27,RAB3C,DNAJB5,CRMP1,DPYSL2,CNNM1,KLHL5,PLXNC1,EIF4G1,SRRM1,DNAJC27,SYNCRIP,GNAS,GRIK2,NXPH3,HS6ST3,NFIA,PDGFRA,FBXW7,SALL1,SLC8A3,LMO3,NCDN,TTBK2,SYN1,FBXW11,UBE2H,AMOT,UBTF,DPF3" Transcription Factor Binding Site V$ER_Q6_02 V$ER_Q6_02 1.49E-04 9.14E-02 9.23E-04 6.46E-03 67 211 "NDRG2,KIAA1324,MADD,CDK13,NOL4,SPAG9,SLC22A6,SLC25A27,SLC4A7,RIMS4,DOCK4,MYADM,SPOCK2,DTNB,EEF1A2,CNNM1,EFNA3,FGF12,FGFR3,FHL1,HPCAL4,FOXF2,DCTN2,TPPP3,GABRG2,GFAP,KIRREL3,HTATSF1,GRIA4,ADAMTS8,GRM1,GABARAPL2,IDH3A,KIF5A,STMN1,MID1,NDUFA5,RCOR2,NEFH,SNTG1,PAX6,CDK14,PCDH18,PLXNB1,SCHIP1,MASP1,REV3L,RGS7,ZNF532,FBXW7,PLPPR3,SATB1,PPM1E,BTBD3,SLC8A3,EFHD1,TET1,SOX2,SPATA7,CAMTA2,STAC2,TCF7,TCF7L2,NR2C2,BCL2L13,GAL3ST3,ADAMTSL3" Transcription Factor Binding Site V$MEF2_01 V$MEF2_01 1.62E-04 9.92E-02 9.86E-04 6.90E-03 44 125 "SLC12A5,BEGAIN,ANK3,ASPH,BMP7,CDC25B,HS3ST5,AKAP12,HAPLN1,RIMS2,HDAC9,MBNL2,EPHB1,EYA1,ABCA8,TBC1D16,ZIC4,FGF12,MYOZ2,GNAS,GRIK1,HAS2,ZNF385B,ITGA7,KCNJ9,KCNN1,TTYH2,SMAD1,MEF2C,SESN3,MYH6,MYO9A,NDP,NFIX,PDGFRA,USP47,SOX2,AGTPBP1,ZFPM2,ITGB3BP,TPM2,TSC1,UBE3A,SSPN" Transcription Factor Binding Site V$PAX4_02 V$PAX4_02 1.62E-04 9.96E-02 9.86E-04 6.90E-03 64 200 "SLITRK1,PITPNM2,ARRB1,ATM,SLC4A4,ATP2A2,ATP6V0A1,DOCK11,C5,CA4,CAST,LDB2,CBFA2T2,CS,CSNK1E,ARHGAP24,ELMO1,CHRDL1,DLX1,WDPCP,MBNL2,SEZ6,NCALD,ETV1,EYA1,ZIC4,AGAP3,MPP6,NTNG2,STMN2,GRIA1,IL1RAPL1,HAS2,ITGA7,ADAM11,MEIS2,MITF,MYBPC1,NEUROD2,NFIA,NFIX,NNAT,OGG1,PAX6,SEMA5B,PCDH18,PDZRN4,POU3F2,SYTL2,PTPRG,RFX3,SLITRK3,BTBD3,SLC20A2,CPEB4,SOX5,POGZ,SMOC1,TCF4,HIF3A,TRPS1,ZIC1,SLC38A1,PRDM8" Transcription Factor Binding Site V$SF1_Q6 V$SF1_Q6 1.66E-04 1.02E-01 1.00E-03 7.00E-03 65 204 "ABAT,NDRG2,SLITRK1,AK2,AMPD3,SEMA7A,APBB1,MADD,CACNB2,DIRAS1,CAMK2G,SPAG9,CHGA,NRXN2,COX4I1,CS,KIAA0586,GIT2,SV2A,EFNB3,PLEKHA1,ELAVL3,RASGRP2,CDHR1,TUBB4A,ARFGAP2,TPPP3,CYP46A1,KIRREL3,LINC01089,PTPN5,NXPH3,IDH3A,KCNC1,KCNK1,KIF5A,POLG,RAB3A,RGS4,RGS7,STX1B,RYR3,SAFB,LRFN5,PPM1E,RPH3A,EPN2,KANSL3,OGDHL,UNC5B,NCDN,MAPK8IP3,MPRIP,STAC2,SLC37A2,CNTN2,SIK3,THRA,FNDC5,HSPBP1,TOM1L2,TBC1D15,VSNL1,SLC30A3,SOCS4" Transcription Factor Binding Site V$MEF2_Q6_01 V$MEF2_Q6_01 1.70E-04 1.04E-01 1.01E-03 7.10E-03 66 208 "ASIC2,SLITRK1,ADCY6,DPP10,PRX,CASK,ASPH,JAZF1,DIRAS1,CAPN3,USP2,DGKI,NOG,CNTN1,HS3ST5,PPP1R16B,CTNND2,RIMS2,HDAC4,DCTN1,RHOBTB1,SV2A,DLG2,DMD,HS3ST2,EEF1A2,HIPK3,MBNL2,ELAVL4,ETV1,FGF12,FGF13,TBR1,MYOZ2,PPARGC1A,GPER1,GABARAPL2,ZNF385B,ITGA7,KCNJ9,KCNN1,KTN1,ADAM11,MITF,MYH6,MYO9A,NDP,PCDH9,PDGFRA,PPM1B,RASGEF1B,RASGRF1,RFX3,YJEFN3,SCN3A,SLC8A3,SLC9A5,SNAP25,SOX5,ARHGAP26,ZFPM2,TPM2,PMEPA1,SSPN,FXR1,GAN" Transcription Factor Binding Site V$ER_Q6_01 V$ER_Q6_01 1.74E-04 1.07E-01 1.02E-03 7.12E-03 67 212 "NDRG2,KIAA1324,PHF12,PKP4,GAS7,B3GALT2,DDR1,NOG,KMT2C,SLC4A7,MAGED1,CREB5,RIMS4,GREB1,SPOCK2,CHRDL1,HS3ST2,NYAP1,DTNB,ERBB4,MRVI1,ZIC4,FGF13,CAMKK2,TBR1,GALNT15,GFAP,KIRREL3,GRM8,IL1RAPL1,GABARAPL2,SHISA6,KCNN3,STMN1,LIFR,MID1,MITF,NKX2-2,PCDH8,PDE1A,CDK14,PPARA,LRRN3,CEP41,PTH1R,FIGN,ZNF532,FBXW7,SATB1,PPM1E,BTBD3,SLC6A9,SPATA7,SPTAN1,SRPK2,PHLDB1,TCF7,SIK3,TPM3,TRPS1,TBC1D15,ZIC1,ZNF32,PRDM10,GAL3ST3,PCBP4,RTN4" Transcription Factor Binding Site RGAANNTTC_V$HSF1_01 RGAANNTTC_V$HSF1_01 1.75E-04 1.07E-01 1.02E-03 7.12E-03 103 355 "ACTN2,ADCY6,ADCY8,SLC24A4,PCDH10,UNC79,OGT,LINC00173,ATP1B3,NOL4,ADAM15,SYNJ1,CACNA1A,CACNA1D,HIP1R,SPAG9,CDH10,CACNA2D2,PLEKHB1,NRXN3,PPT2,DNAJB5,MAP4K4,CNTFR,COL4A5,CREM,GREB1,RIMS2,HDAC4,DAPK1,DBI,DMD,SHANK1,DMTF1,ABCC5,EFNB3,MBNL2,EGR3,PLXNC1,EIF4G2,ELAVL4,RASGRP2,CLVS1,FHL1,FLNC,CAMKK2,ATP2C1,STAG2,GAD1,GAD2,NEK6,CYP46A1,RUNDC3A,GNAS,GPR17,GRIK1,GRM1,GRM8,GSN,CLASRP,ELOVL5,HSPA1L,SHISA6,RBPJ,IL6ST,SMAD1,MAP2,MAP6,MARK3,MAT2A,SHC3,MEF2C,MMP16,MOBP,HS6ST3,NNAT,PAK3,ENPP2,PLEC,PPP2R2C,PPP2R5C,PTHLH,RALGDS,RFX3,CARF,RORB,RTN1,TRERF1,SP4,TAB2,FNDC9,ANKRD28,POPDC3,CHST8,TPM2,TRPS1,EIF4ENIF1,AMOT,XPO1,LMAN2L,ADAMTS9,SCG2,NETO2" Transcription Factor Binding Site V$HP1SITEFACTOR_Q6 V$HP1SITEFACTOR_Q6 1.76E-04 1.08E-01 1.02E-03 7.12E-03 61 189 "ZBTB10,ATP2B3,CA4,CDK11B,NOG,NRXN3,MAP4K4,CNTFR,NCOR1,CS,SNCAIP,HDAC9,PARD6A,CHRDL1,DLX1,DMD,DMTF1,DPYSL2,MBNL2,EIF4G2,CALCRL,SEZ6,NCALD,POLK,IP6K2,SYNCRIP,STAG2,GCNT2,MSTN,ADAM28,EML4,HAPLN2,IGF1,SFXN5,SMAD1,MBNL1,ADAM11,MEIS1,NFIX,ZNF827,PIK3R1,SCHIP1,LRRN3,PRKACB,MAPK10,RGS3,LRFN5,ASIC4,PREX2,SOX2,KIF1B,NPAS3,MPRIP,ANKRD28,PJA1,PUM2,PCDHA7,FLRT1,VLDLR,XPO1,ZIC1" Transcription Factor Binding Site V$GATA_C V$GATA_C 1.77E-04 1.09E-01 1.02E-03 7.12E-03 68 216 "ADORA3,ADGRF5,SPTBN4,B3GALT2,BTRC,CAST,CLDN10,RGN,LGI1,NRXN3,PPT2,CTNND1,HEPH,DMD,HS3ST4,EDN1,ELAVL4,DMTN,ETV1,EYA1,ZIC4,FGF14,GABBR1,CPLX2,GATM,GBX2,PCDH11X,GRIK3,MAP4K5,KLF12,HPSE2,CPT1C,ZNF385B,KCNK3,LIFR,LMO2,MBD1,CHST6,KCTD6,MID1,MITF,MSR1,HS6ST3,SLCO1C1,SNTG1,CCSER2,MASP1,RORB,SATB1,TNFRSF19,PPM1E,SPHKAP,SOX5,SOX10,ZHX3,ZSWIM8,GSE1,TACC1,FBXW11,TEK,C5orf64,TPM3,PRR18,UBE2H,UBE3A,AMOT,P2RY12,ZIC1" Transcription Factor Binding Site V$GATA1_01 V$GATA1_01 1.86E-04 1.14E-01 1.05E-03 7.31E-03 63 197 "ACLY,ADD3,SPOP,ANK3,PHF12,ATP2B2,DOCK11,BMP7,CDC27,CRLF1,RAB3C,CLU,CLTA,CLOCK,FEZ2,GRIN3A,DPYSL2,RCAN1,DYRK1A,PLXNC1,ELAVL2,EPHB1,CLVS1,WAC,CACNG2,ZIC4,SYNCRIP,STAG2,GABRA3,RAPGEF6,KAT7,LSAMP,NFIA,NTRK3,ZNF827,PCDH8,ENPP2,PENK,ING3,POU3F4,PPP2R2B,PROX1,RIT2,STX1B,SALL1,SLC4A3,SLC8A3,SNCA,TRERF1,SOX2,ZNF423,KIF1B,LMO3,LRRC4,NCDN,STAC2,TF,NR2E1,HIRA,UBE2H,FAM181B,ZIC1,ZIC3" Transcription Factor Binding Site V$NGFIC_01 V$NGFIC_01 1.86E-04 1.14E-01 1.05E-03 7.31E-03 63 197 "ACTN1,APP,MADD,CACNA1A,CACNA1E,CDH2,CLTC,CRY2,HDAC9,MATR3,G3BP2,ATL1,EGR3,ELAVL3,IP6K2,SYNCRIP,AGAP3,GABRB1,PCDH17,GRIN1,KAT7,GUCY1A2,GABARAPL2,KCNA1,KCNB1,KCNC1,KCND2,KCNN2,ARHGAP12,MAN2A2,MEF2C,GIT1,MSI1,NRDC,NRGN,NTRK3,ZNF827,PCSK2,SH3KBP1,RBBP6,RFX4,NUDT11,KCNIP2,FAM192A,LRFN5,SEC14L1,TRA2B,SH3GL3,CLSTN1,FAM214B,SNAP25,SPTB,LRRC4,GSE1,NUDT10,PJA1,WASHC4,PCDHAC2,ICAM5,TPM4,AMOT,UBTF,VGF" Transcription Factor Binding Site TGATTTRY_V$GFI1_01 TGATTTRY_V$GFI1_01 1.96E-04 1.20E-01 1.09E-03 7.65E-03 75 244 "SLC25A25,ADCY8,CASKIN1,NRP2,JAZF1,CACNA1E,LDB2,FOXN3,CHN1,NRXN3,NRXN1,ZNF521,NECTIN3,CREB5,CTNND1,RIMS2,CHRDL1,DMD,HS3ST4,CALN1,CDON,WDPCP,PHC2,ELAVL4,ZIC4,FGF14,IP6K2,FYN,GABRA1,JPH4,PPARGC1A,RAB30,GPM6A,GPR17,GRB10,JAK1,LSAMP,MEF2C,MEIS2,MID1,MSR1,MYBPC1,NAP1L3,NOVA1,PCDHGC3,CDK14,CCSER2,POU3F2,MAPK8,MAPK10,RASGRF2,RXRG,SALL1,SARS,MRAS,ITSN1,FRMPD1,SNAP25,SNCA,TRERF1,SOX5,NMNAT2,SRPK2,CLSTN2,POGZ,ROBO3,TCF12,RALYL,ZFPM2,CRB1,TSC1,FLRT1,ZIC1,CAB39L,JMJD1C" Transcription Factor Binding Site V$PAX4_03 V$PAX4_03 2.03E-04 1.24E-01 1.12E-03 7.84E-03 67 213 "ASIC2,USP31,AGT,SEMA6A,ANK2,ARHGAP5,BCL2L2,BTK,CDK5R2,CAMK2G,SPAG9,COL11A2,CS,PHACTR3,PHYHIP,DCTN1,C2CD2L,DPYSL2,ABI2,CERCAM,EMX2,TUBB4A,FGF11,FGFR1,MEX3B,FLT1,TPPP3,STAG2,C1QL1,PCSK1N,GNAO1,STMN2,ZIC5,SCRT2,KCNN2,KCNN3,STMN1,MGAT3,MOV10,HS6ST3,MXI1,MYL3,NEUROD2,NFIX,NHLH1,NRGN,NTRK2,PBX1,ZDHHC8,NLGN3,SERPINI1,PTPRN,ZNF532,TRIM46,SP4,SPTAN1,LMO3,NCDN,PLCB1,HIF3A,ZFP91,ZIC2,SH3GLB2,CA10,PRDM10,PCBP4,SLC4A10" Transcription Factor Binding Site V$AP4_Q5 V$AP4_Q5 2.06E-04 1.27E-01 1.13E-03 7.91E-03 68 217 "ABR,FZD9,AMPH,PTCH2,CHRD,BACH1,CACNB2,ARHGEF2,PCYT1B,ZNF385A,ATRNL1,DOCK4,ARHGAP24,HDAC4,PABPC5,BRINP1,DMD,HS3ST4,RASL12,EYA1,NBEA,DLL3,IP6K3,RAB30,GPM6B,GRIK3,GRIN2D,LINC01089,PSIP1,ATOH8,CELF3,PADI2,HAPLN2,HPCA,IGF1,KCNH2,KCNMA1,KCNN2,MBP,KSR2,OPCML,PDE3A,PRKCG,MASP1,SYTL2,RASGRF2,RGS7,RTKN,RXRG,SALL1,SEMA6D,TNFRSF19,CPEB3,PREX2,SLC8A3,NCDN,PHLDB1,ANKRD12,TCF7,TPM3,KCNE5,UBE2H,AMOT,VGF,SLC26A10,PRDM8,NAV3,PCBP4" Transcription Factor Binding Site V$NKX25_02 V$NKX25_02 2.27E-04 1.39E-01 1.23E-03 8.63E-03 65 206 "SLC25A25,KLHL13,BBOX1,ANK3,SLC4A4,CA4,CFL2,FOXN3,NRXN1,WHRN,NECTIN3,DOCK4,HDAC9,DLG3,DLX1,DMD,HS3ST2,MBNL2,ELAVL2,SEZ6,EYA1,FLT1,TBR1,ABLIM2,GAD1,ATF7,HAS2,KLF12,HPSE2,GABARAPL2,KCNJ3,LRP1B,MEIS2,NELL2,NTRK2,PCDH9,SEMA5B,ANLN,KCTD15,PDZRN4,PRRX1,CEP41,CNNM2,RAB5B,SLC6A15,RGS12,FBXW7,PPM1E,TET1,CXXC4,ZNF423,LMO3,TAB2,ROBO3,FBXW11,TBL1X,TCF12,NSD1,SIK3,HHIP,SEZ6L,TPM2,FLRT2,VLDLR,DPF3" Transcription Factor Binding Site V$TST1_01 V$TST1_01 2.39E-04 1.47E-01 1.29E-03 9.02E-03 68 218 "TTYH1,CSMD3,KLHL13,BEGAIN,B3GALT2,ADAM23,JAZF1,CACNA2D2,CFL2,NRXN3,CABP1,RNF14,SIPA1L1,SLITRK5,SCRN1,HEPH,DLG2,DMD,HS3ST4,RCAN1,ELAVL2,ELAVL4,OLIG2,PIPOX,CLVS1,ZIC4,FOXG1,STAG2,NEK6,PCDH17,GPM6A,GRB10,CELF3,HAS2,SCRT2,ZNF385B,MAP2,MPP2,SESN3,PAX6,PCDH8,PDE1A,PDE4B,CDK14,SEMA5B,KCTD15,PCDH18,PURG,ING3,PRKACB,RAP1GDS1,FIGN,RFX3,ZNF532,RTN1,SLC1A7,BTBD3,RIMS1,SMOC1,ANKRD28,RALYL,HEY1,NR2E1,ZNF384,PORCN,ZIC1,SLC17A6,KLHDC1" Transcription Factor Binding Site V$TFIII_Q6 V$TFIII_Q6 2.48E-04 1.52E-01 1.31E-03 9.17E-03 56 172 "NDRG2,MAP4K3,DGKZ,ARHGAP5,ASCL1,PTCH2,ATP1A2,BCL2L2,CBFA2T2,CHRM1,MICAL2,CNNM1,PLXNC1,ELAVL3,EMX2,APC2,FGF11,FGF14,FOXG1,CELF1,GNAS,NXPH3,SHISA6,MYLK2,KCNJ10,ADAM11,MSI1,RCOR2,NFIX,NKX2-2,NNAT,NODAL,PBX1,PCDH9,PRRX1,PPP2R5E,VPS13C,RAB5B,STX1B,SALL1,TRIM46,SHANK2,WDTC1,LMO3,NCDN,CNTN2,TCF12,THRA,UBTF,XPO1,SF1,ZIC2,CELF4,CA10,FBXO36,JPH3" Transcription Factor Binding Site V$RREB1_01 V$RREB1_01 2.48E-04 1.52E-01 1.31E-03 9.17E-03 56 172 "NDRG2,SLC12A5,GPR158,PPFIA2,ARHGAP5,CALM1,FMNL3,CPNE6,CLTC,ZNF385A,PHACTR3,DCTN1,DLX1,NYAP1,RBM12,EGR3,EIF4G1,ELAVL4,EMX2,CACNG2,PPP1R1B,FLNC,STAG2,AHCYL1,GLYR1,GNAO1,GRIN2D,KLF12,KCNA1,KCNN3,MXI1,MYH7,MYL3,NEUROD2,NKX2-2,NOVA2,NTRK3,ZDHHC22,PLXNB3,PURG,ING3,TNPO2,PPP3CB,ZNF532,TRIM46,ZNF821,ARX,FBXO11,TRERF1,SP4,NCDN,PLCB1,WRN,CELF4,ST7,FBXO36" Transcription Factor Binding Site V$AP4_Q6 V$AP4_Q6 2.56E-04 1.57E-01 1.34E-03 9.38E-03 57 176 "EMILIN3,ARID1A,AMPH,GAS7,CADPS,PTCH2,BACH1,BCL2L2,CACNA1G,CACNB2,ARHGEF2,PCYT1B,ZNF385A,DOCK4,ARHGAP24,HDAC4,SPOCK2,PABPC5,HS3ST4,WDPCP,BSCL2,RASL12,EYA1,FGF12,SORBS1,DLL3,RAB30,GNG3,GRIK3,CELF3,NXPH3,HAPLN2,KCNMA1,KCNN2,SCAMP5,NPPA,KSR2,PDE3A,PLXNB3,CNNM2,SYTL2,RAB3A,RASGRF2,RGS7,RTKN,RXRG,CPEB3,WDTC1,ZSWIM8,PHLDB1,TCF7,TPM3,FNDC5,KCNE5,UBTF,VGF,JMJD1C" Transcription Factor Binding Site V$OCT1_Q5_01 V$OCT1_Q5_01 2.81E-04 1.72E-01 1.46E-03 1.02E-02 69 223 "ASIC2,ADORA1,ADORA2A,MTUS1,ALK,ATP2A2,BTK,LDB2,CD86,CBFA2T2,CDH10,SYNPR,NRXN3,NRXN1,RAB26,PCYT1B,RTTN,DAPK3,DLG2,DLX1,DMD,DPYSL2,RCAN1,SUGP2,ETV1,EYA1,FGF12,FGF14,HPCAL4,FOXG1,SEMA6C,PCDH11X,GPM6A,KCNN3,MID1,MYBPC1,NDP,NFIA,NOS1,PAX6,PCDH8,PDE4D,GPR85,TMOD2,PRRX1,NXPH1,POU3F4,PPP2R2B,PPP2R5C,CEP41,PTHLH,SLC6A15,MRAS,ITSN1,SH3GL3,ATF7IP,CXXC4,KIF13A,TRERF1,ZNF423,LMO3,TCF12,THRA,TLL2,TPD52,MGAT5B,PLPPR2,VSNL1,FSTL5" Transcription Factor Binding Site V$CHOP_01 V$CHOP_01 2.84E-04 1.75E-01 1.47E-03 1.03E-02 61 192 "SLC12A5,AP2A1,CASK,ZBTB10,ATM,CACNA1E,CACNB2,CAST,CARS,ARHGEF6,CNTFR,SNCAIP,SOCS5,CTNND1,DPYSL2,PLXNC1,GPHN,FGF11,FGF14,SYNCRIP,TPPP3,GABRA1,PCDH17,PPARGC1A,KLF12,HMGB1,KCNN2,STMN1,MAP4,MBNL1,TM6SF1,MEF2C,MEIS1,KITLG,SESN3,MIR4697HG,NFE2L2,NTRK2,NTRK3,PCDH9,CDK14,SEMA5B,KCTD15,PCDH18,PDZRN4,ZNF532,SARS,LRRTM4,FBXO11,SLITRK3,RIMS1,TRERF1,NPAS3,LMO3,SRPK2,ANKRD28,TBL1X,AHCYL2,ITGB3BP,SH3GLB2,JMJD1C" Transcription Factor Binding Site V$HLF_01 V$HLF_01 3.07E-04 1.89E-01 1.57E-03 1.10E-02 65 208 "ADRB2,OSBPL6,CASK,ADGRB3,BSN,CALM1,USP2,CDC42,CDH10,CHN1,NDST3,ZFYVE9,SLC24A2,CREB5,CSNK1E,DLX1,DMD,ECM2,EGFR,MBNL2,ELAVL4,CALCRL,EPB41,F5,CACNG2,ACSL4,IP6K2,FOXO3,MPP6,GBX2,EML4,HRH3,MAP4,MEIS2,MPP2,NEUROD1,NPTX1,OCRL,PCSK2,PDE4D,GPR85,PIK3R1,PTHLH,ZDHHC14,RGR,ROBO1,FBXW7,SEMA6D,LRRTM4,SHMT2,PREX2,EPN2,PKNOX2,FAIM2,FNBP1,POGZ,KLHL7,SYT11,PLCB1,TAC1,CLASP1,TNS2,RBFOX2,SMARCAD1,JPH3" Transcription Factor Binding Site V$OCT_Q6 V$OCT_Q6 3.20E-04 1.97E-01 1.63E-03 1.14E-02 68 220 "ADORA1,ADORA2A,MTUS1,ALK,ATP2A2,BTK,LDB2,CD86,CBFA2T2,SYNPR,NRXN3,NRXN1,RAB26,PCYT1B,RTTN,HDAC9,DAPK3,DLG2,DLX1,DMD,DPYSL2,RCAN1,SUGP2,ETV1,EYA1,FGF12,FGF14,HPCAL4,FOXG1,SEMA6C,GPM6A,KCNN3,MID1,SESN3,MYBPC1,NDP,NFIA,PAX6,PCDH8,PDE4D,GPR85,TMOD2,PRRX1,NXPH1,POU3F4,PPP2R2B,CEP41,PTHLH,SLC6A15,MRAS,ITSN1,SH3GL3,ATF7IP,CXXC4,KIF13A,TRERF1,ZNF423,LMO3,TCF12,THRA,TLL2,TPD52,TSC1,MGAT5B,PLPPR2,VSNL1,FSTL5,PRDM10" Transcription Factor Binding Site V$P300_01 V$P300_01 3.32E-04 2.04E-01 1.67E-03 1.17E-02 61 193 "CSMD3,SLITRK1,KCNAB2,ASCL1,ADAM15,CACNB2,PTBP2,CAMK2D,CANX,CAST,AKAP12,SLITRK5,ELMO1,DLX1,DMD,DMTF1,DPYSL2,EFNB3,SUGP2,EGR3,ELAVL4,RASGRP2,EPHB1,ZIC4,PPP1R1B,FGF12,FGFR1,PRKAG2,SYNCRIP,STAG2,GABRA1,NKX6-2,ATP8A2,GJB1,GRM7,GSN,SHISA6,KCNN3,NLGN3,SERPINI1,PIK3CD,RETREG1,PLP1,PPP3CA,PPP3CB,PRKACB,PSMD13,RFX2,SMPD3,SLC12A4,WDTC1,SRPK2,ERBIN,GSE1,SYN1,PCDHAC2,PUM2,ZIC1,ZIC3,ZNF23,DPF3" Transcription Factor Binding Site YNTTTNNNANGCARM_UNKNOWN YNTTTNNNANGCARM_UNKNOWN 3.42E-04 2.10E-01 1.71E-03 1.19E-02 24 58 "GPR158,LDB2,SYNPR,CNN3,DMD,KLHL5,ELAVL2,EYA1,FGF12,FGF14,FOXG1,GABRA1,GABRG1,GPM6A,HPSE2,ZNF385B,LRRTM1,KCNA2,MYBPC1,OMG,PDE4D,KIF13A,FGD4,TLL2" Transcription Factor Binding Site WTTGKCTG_UNKNOWN WTTGKCTG_UNKNOWN 3.63E-04 2.23E-01 1.80E-03 1.26E-02 116 415 "ARID1A,SLC25A25,SPARCL1,ABCD2,DPP10,PPFIA2,PRX,ZBTB10,CACNA1G,CACNA1E,REPS2,CDH10,ARHGAP33,RAB3C,NRXN1,CNN3,PCYT1B,SLC4A7,BAG4,ZNF385A,PHACTR3,CTNND1,HDAC9,RASSF2,IST1,PITPNC1,HEPH,ELMO1,DLG3,DMD,OLIG1,USP3,TOM1,ELAVL3,ELAVL4,GPHN,APC2,FGF13,MEX3B,SYNCRIP,DACH2,CSPG5,RAPGEF6,GATM,GFRA1,PCDH17,RND1,STARD3,HAS2,BACH2,ELOVL5,HMGB1,SCRG1,HPSE2,TLX1,ATCAY,NKD1,SCRT2,KCND3,KCNH2,STMN1,MDFI,MEIS1,MN1,MYT1,NCAM1,NDP,SLC11A2,NTRK2,PALM,PCDHGC3,GPR85,SEMA5B,PIK3R1,SMOX,POU3F4,PPP2R2B,RAB39A,MASP1,RAB5B,ARID4A,ZNF532,EMID1,ABLIM3,FAM214B,TSNAXIP1,SOX10,LMO3,POGZ,STAC2,SEPT3,ANKRD12,ADGRL3,TCF4,CLASP1,RALYL,CHST8,TIAM1,HEY1,TLL2,TPM1,WBP2,NR2C2,DNAJC12,XPO1,SF1,PCDH20,ZIC2,ZNF32,CRB2,ZNF189,DPYSL5,STMN4,LMAN2L,JMJD1C,ADAMTS10" Transcription Factor Binding Site V$GR_Q6 V$GR_Q6 3.66E-04 2.24E-01 1.80E-03 1.26E-02 67 217 "ADCY6,ADORA1,ABCD2,LRCH2,PKP4,PRX,B3GALT2,ADGRB3,FGF17,BTK,USP2,AP4M1,LARGE1,NOG,CHRM1,RAB3C,HAPLN1,GREB1,CTNND2,RIMS2,DLX1,SGK2,ELAVL2,ELAVL4,EYA1,FGF12,FGF13,IP6K2,SYNCRIP,AGAP3,RAB30,HMGB1,HNMT,NEGR1,USP54,INSM1,ZNF385B,LRRTM3,KCND2,LIFR,MBNL1,MBP,MEIS2,MID1,MITF,NCAM1,RCOR2,NNAT,PCDH8,PDE2A,PCDH18,SCHIP1,PRRX1,PPP2R2B,PRKCG,RGS3,ZNF532,FBXW7,LGI3,ZNF423,LMO3,SRPK2,NCDN,KLHL7,FGD4,DAAM2,CA14" Transcription Factor Binding Site GGGYGTGNY_UNKNOWN GGGYGTGNY_UNKNOWN 3.78E-04 2.32E-01 1.84E-03 1.29E-02 142 524 "KCNH8,ABR,SLITRK1,ADCY8,SEMA6A,SRPX,OGT,MAP4K3,PPFIA2,APBB1,KCNAB2,MAGEE2,DGKZ,PRX,IGDCC4,ATP1A1,ATP1A3,BCS1L,MTMR3,GPC2,CACNA1B,KALRN,CANX,CAST,AP4M1,CRLF1,B4GALT6,CPNE6,CNTFR,COL9A1,COL11A2,ACBD5,NRG2,CRMP1,GDA,BOC,MYADM,IST1,SPOCK2,DBI,ARMCX2,WDR20,NYAP1,DPYSL2,ABI1,EDIL3,ATL1,EFNA3,PLXNC1,ELAVL3,EFS,ARMCX1,PTK2B,SCML2,FHL1,VTI1B,DCTN2,ATP2C1,CELF1,DACH2,STAG2,GABRA3,CHL1,GAP43,RAB30,ATF7,GPR22,LPAR4,GRIA1,NR3C1,GRM3,MAP4K5,CELF3,HPCA,DHX35,IGSF1,KCNA6,KCNC1,KCND1,KCNH2,KCNK3,KIF5A,LAMP2,STMN1,PIK3AP1,MITF,MOV10,MPP2,PTOV1,NCAM1,RCOR2,NELL2,NFYA,NOVA2,NTRK2,NUCB1,PAK3,PALM,PCDH9,PLEC,PMP22,MAGEL2,MBOAT7,EPB41L4B,SH3KBP1,RAB39A,PRKCG,CNNM2,PSD,RGS3,RTKN,RTN1,SCN8A,ITSN1,FAM214B,NAPB,TRERF1,TAB2,CAMTA2,SMOC1,EPB41L3,STX1A,GSE1,EXOC7,SYNE1,DOCK9,HIF3A,SIK3,THRA,SEZ6L,KCNE5,AMOT,UCHL1,BCL2L13,PLPPR2,XPO1,LGI4,DPYSL5,STMN4,SEMA3B,NAV2,PCBP4" Transcription Factor Binding Site V$POU6F1_01 V$POU6F1_01 3.87E-04 2.38E-01 1.86E-03 1.30E-02 61 194 "BEGAIN,C5,CAMK2D,HIP1R,SPAG9,CBLN1,CFL2,FOXN3,SYNPR,FHL5,CREB5,RHOBTB1,DLX1,TENM1,ELAVL2,EMX2,ETV1,EYA1,EFEMP1,FGF13,MPP6,ABLIM2,FYN,STAG2,NEK6,PPARGC1A,NTNG2,GRIK3,GRIK4,IL1RAPL1,ZNF385B,CDH20,KCNMA1,MBNL1,ADAM11,MEIS1,MEIS2,PPM1L,STK32C,MYT1,NCAM1,NDP,ZNF827,TMIE,KCTD15,PCDH18,PDZRN4,PTH1R,RFX3,PRIMA1,FBXW7,SEPHS1,SOX5,LMO3,SYT5,NSD1,PCDHA3,ZFPM2,RBFOX2,SCG2,RTN4" Transcription Factor Binding Site V$PTF1BETA_Q6 V$PTF1BETA_Q6 3.87E-04 2.38E-01 1.86E-03 1.30E-02 61 194 "SLITRK1,BBOX1,ANK3,CASK,ATP1B3,PTBP2,SLC25A14,CCKBR,ASIC3,MAGED1,ZNF521,SNCAIP,CSNK1E,SLITRK5,PUM1,ST18,RASSF2,PHYHIP,DLG4,DMD,EEF1A2,PLXNC1,EIF4G1,BSCL2,NCALD,CLVS1,FGF14,FOXO3,SYT3,GABRA1,PCDH17,PPARGC1A,GNG3,FERMT2,IL1RAPL1,NXPH3,LRRTM1,ITGA7,MAP4,NPPA,PCDHGC3,KCTD15,PMP22,ROBO1,LRRTM4,SLITRK3,SLC8A3,RIMS1,TRERF1,SMOC1,TBL1X,RALYL,DICER1,HHIP,THRA,KCNE5,UBTF,NPDC1,XPO1,ZIC1,ZIC3" Transcription Factor Binding Site V$LMO2COM_01 V$LMO2COM_01 4.00E-04 2.46E-01 1.89E-03 1.32E-02 63 202 "ADCY8,MTUS1,KIAA1324,SORCS2,SEMA6A,ATP2B3,CALB1,MAP7,SHISA7,NEURL1,CDH2,NUMBL,B4GALT6,ZNF521,NRG2,PPP1R16B,MYADM,DCTN1,ELMO1,C2CD2L,PARD6A,DMTF1,EPB41,FGF11,FGF12,FGR,AGAP2,AGAP3,NBEA,NSG2,GFRA1,GNAS,STMN2,GRIN1,PSIP1,HAPLN2,ITGA7,KCNB1,KCNN3,LMO1,MAPT,COMMD5,MDGA1,NHLH1,PLEC,PPP2R5C,PRKCZ,CNNM2,OXR1,KCNIP2,TRAPPC13,HES6,SMPD3,RAP1GAP2,SYT4,SYNE1,DOCK9,PCDHA6,PCDHA1,HIF3A,TJP1,NR2E1,PRDM10" Transcription Factor Binding Site V$SPZ1_01 V$SPZ1_01 4.00E-04 2.46E-01 1.89E-03 1.32E-02 63 202 "ASIC1,SLITRK1,PHF12,ARNTL,BCL7A,FGF17,CDK5R2,CNTFR,CRMP1,PITPNC1,DCTN1,DLG2,NYAP1,SHANK1,DPYSL2,RBM12,EIF4G1,EIF4G2,EPHB1,SRRM1,PPP1R1B,SEC24B,FGF13,SYNCRIP,STAG2,GPM6B,SCRT2,KCNC1,KCNK2,KCNN2,MEIS2,MOV10,CNOT4,NPPA,NTRK3,PCSK2,SLC25A23,PRRX1,PPP2R5C,PRKCG,PSD,CXXC4,RIMS1,WDTC1,SOX3,SOX10,SOX15,SP4,CAMTA2,NCDN,STAC2,TNS2,AHCYL2,HIF3A,TIAM1,ZFP91,TPM3,SSBP2,HIRA,TOM1L2,XPO1,ADAMTS9,SLC17A7" Transcription Factor Binding Site V$CDC5_01 V$CDC5_01 4.17E-04 2.56E-01 1.95E-03 1.37E-02 66 214 "ARNTL,NOL4,ADGRB3,NRXN3,CREB5,CSNK1G3,CTNND1,MAML1,DGKB,CHRDL1,DLG2,TENM1,EYA1,ACSL4,FGF12,FYN,STAG2,SALL3,NEK6,GFRA1,PPARGC1A,GK,ADAMTS6,KLF12,BACH2,ITPKB,MBNL1,MN1,SESN3,MXI1,MYH6,NOVA1,NPTX1,ZNF827,SNTG1,PBX1,PCDHGC3,PCDH8,ENPP2,GPR85,PIK3R1,KCTD15,PDZRN4,PRRX1,ING3,PPP2R2B,PRKACB,RORB,SALL1,LRFN5,SCN7A,BTBD3,CPEB4,FNBP1,LMO3,SAMSN1,SYT4,KLHL4,CLASP1,TNS2,ZFPM2,TRPS1,UCHL1,KCNK12,NDRG4,ADAMTS9" Transcription Factor Binding Site SYATTGTG_UNKNOWN SYATTGTG_UNKNOWN 4.34E-04 2.66E-01 2.02E-03 1.41E-02 59 187 "CASK,BCL7A,FGF17,BSN,WASF1,CAMK2A,CFL2,RAB3C,CLU,NECTIN3,FEZ1,PYGO1,DLX1,ABI1,CELSR3,EGR3,PLXNC1,EIF4G1,FGF14,AHCYL1,GALC,ZNF274,PCSK1N,GPM6A,GRIK3,ATE1,IL1RAPL1,ELOVL5,KCNF1,SMAD1,MEIS1,MMP16,ADAM22,MYL3,NNAT,OMG,OPHN1,PCDHGC3,PCDH8,PDYN,PLP1,PPP2R5C,MAPK10,LAMA1,ANKHD1,RFX4,PRIMA1,ZNF532,RTN1,KIF21A,MBD5,TSNAXIP1,LMO3,RALYL,NSD1,C5orf64,TPM3,CA14,GJC2" Transcription Factor Binding Site V$FOXD3_01 V$FOXD3_01 4.39E-04 2.69E-01 2.03E-03 1.42E-02 53 164 "ATP2A2,ADGRB3,SYT6,CAST,CHN2,NRXN3,PCYT1B,CREB5,SNCAIP,CSNK1G3,FGFR1OP2,DMD,E2F5,EPHB1,FYN,STAG2,MSTN,PCDH17,MSL3,GNAO1,GRM3,HAS2,KLF12,ATCAY,LRRTM3,LRRTM1,KCNA4,SMAD1,MEF2C,SCG3,NEUROD2,NFIX,NOVA1,PIK3C2A,KCTD15,SYTL2,ARID4A,PRIMA1,CYB561D1,SGK1,FBXO11,SLITRK3,KDM3A,LMO3,POGZ,MESP1,NCDN,ANKRD28,TCF7L2,ARHGEF12,HHIP,P2RY12,CELF4" Transcription Factor Binding Site V$AHR_Q5 V$AHR_Q5 4.64E-04 2.85E-01 2.12E-03 1.49E-02 55 172 "ASIC2,ASIC1,SLITRK1,AXIN2,NR0B1,DOC2A,AMPD2,BIN1,PPFIA2,USP37,ARRB2,ASCL1,ASPH,CACNA1B,CAMK2D,CHRM1,RAB33A,ZNF521,FGFR1OP2,GIT2,PITPNC1,ATL1,ABI2,ELAVL4,EPHB1,WAC,CACNG3,MEX3B,FOXO3,DOT1L,GAD2,STARD10,NR3C1,RBPJ,MEIS1,MEIS2,ZNF827,ING3,PPP2R2B,PSD,REV3L,TRAPPC13,SEC14L1,BTBD3,SLC9A5,SORCS3,LMO3,STAC2,ZFP91,VLDLR,SF1,ZIC2,RTN4,FBXO36,SNX14" Transcription Factor Binding Site V$GFI1_01 V$GFI1_01 4.85E-04 2.98E-01 2.21E-03 1.54E-02 67 219 "ADD3,MAP4K3,ADGRB3,JAZF1,CACNB2,CAMK2D,ARHGEF2,CHRM1,NRXN3,NGEF,SLC4A7,ZNF521,CREM,CREB5,PHACTR3,PHYHIP,KLHL3,CALN1,CDON,SLC25A18,EDN1,SGK2,ELAVL4,RCAN2,CLVS1,CACNG3,ZIC4,MEX3B,TBR1,JPH4,PPARGC1A,GPR17,PLCD4,KLF12,STMN1,MBNL1,MEF2C,MEIS1,MSR1,NCAM1,NFIA,DDR2,PBX1,PCDH8,PDE4D,CCSER2,PTHLH,PRIMA1,TRAPPC13,ITSN1,CPEB3,PREX2,SOX5,SOX15,LMO3,EXOC7,TCF4,TCF12,PCDHAC2,ZFPM2,ICAM5,ZIC1,ZIC3,CELF4,PRDM10,JMJD1C,DPF3" Transcription Factor Binding Site V$NCX_01 V$NCX_01 5.00E-04 3.07E-01 2.26E-03 1.58E-02 47 142 "SLC24A4,PITPNM2,ANK2,PHF12,PTCH2,ATP1A3,CACNA2D2,NRXN1,MAP4K4,HAPLN1,SNCAIP,WDPCP,PLXNC1,ELAVL2,ELAVL4,EMX2,ETV1,PTK2B,IP6K2,TBR1,GAP43,GNAS,GNG4,LPAR4,KLF12,KCND2,LMO1,MAP4,MOV10,SESN3,NOS1,PCDH9,SEMA5B,PDZRN4,SDK2,ING3,RAB39A,ZCWPW1,RFX3,ZNF532,ATP8B4,SLC1A7,LMO3,ANKRD28,ROBO3,THRA,CA10" Transcription Factor Binding Site V$DBP_Q6 V$DBP_Q6 5.36E-04 3.29E-01 2.40E-03 1.68E-02 63 204 "SEMA6A,ANK2,ARRB2,BTK,HAPLN1,CRY2,DMD,MBNL2,OLIG2,SEZ6,SYNCRIP,ATP2C1,JPH4,MYOZ2,GBX2,GFRA1,PCDH17,PPARGC1A,PCDH11X,GPM6A,GRIK1,IL1RAPL1,SOX21,MAP4K5,OPALIN,ZIC5,ZNF385B,ITPKB,HECTD2,MBNL1,KCTD6,MID1,MITF,MN1,MXI1,MIR4697HG,NEUROD2,NFIA,NFIX,PCDH8,PCDH9,GPSM2,PTPRG,ARID4A,RFX3,KIRREL1,FBXW7,BTBD3,DHX30,FAM214B,SLC6A9,ZNF334,LMO3,SRPK2,GANAB,PUM2,ITGB3BP,TIMP4,UBE2H,VSNL1,ADAMTS9,GOPC,FAM13C" Transcription Factor Binding Site TGTTTGY_V$HNF3_Q6 TGTTTGY_V$HNF3_Q6 5.42E-04 3.33E-01 2.40E-03 1.68E-02 158 596 "ADARB2,SEMA6A,OGT,APC,BCAS1,PRX,ARRB2,ATP2A2,B3GALT2,ADAM15,ADGRB2,C5,HIP1R,KYAT1,REPS2,CDH10,CHN2,CHRM1,NRXN3,ARHGEF6,CNTN1,HS3ST5,CREB5,HAPLN1,CRY2,CNTNAP2,ARHGAP32,DCT,DCTN1,CHRDL1,DLG2,DMD,DSCAM,ELAVL4,EML1,LRRC17,EYA1,CACNG2,ZIC4,PPP1R1B,FGF14,IP6K2,ATP2C1,STAG2,GABRA2,GABRB1,JPH4,ARPP21,NEK6,IQGAP2,GBX2,KIRREL3,PCDH11X,GOLGB1,GPM6A,GPR37,GRIK1,GRIK2,ATOH8,KLF12,HPSE2,HNF4G,SHISA6,IGFBP1,NKD1,ZIC5,IL11RA,ITPKB,SHC3,MEF2C,MEIS1,MEIS2,MITF,SESN3,BLOC1S2,SCG3,MXI1,NCAM1,NDP,NEUROD1,NEUROD2,NFIA,NKX2-2,OMG,ZNF827,PCSK2,PDE3B,PDE4D,PDGFRA,PDYN,CDK14,SEMA5B,CCSER2,PURG,SDK2,PPP2R2B,MAPK3,MAPK10,MASP1,PTPRG,RAB5B,ZDHHC14,FIGN,RFX3,RFX4,RGS3,RIT2,LGI2,KIRREL1,ROM1,RPE65,RTN1,SGK1,CPEB3,EPN2,DHX30,SLC6A1,SLC14A1,SLCO1A2,SORCS3,SNAP25,SNCB,KIF13A,SOX2,SOX5,ZSWIM8,SP4,NMNAT2,SRPK2,SMOC1,ST5,NCDN,SYNE2,ROBO3,PDLIM2,FBXW11,TCF4,TCF7L2,DOCK9,NSD1,PUM2,TF,THRA,TIMP4,TJP1,C5orf64,WBP2,TRPS1,CA14,UBE2H,FLRT1,VSNL1,WRN,ZIC1,NAV3,FAM13C,ADAMTS10,RNF146" Transcription Factor Binding Site V$OCT1_Q6 V$OCT1_Q6 5.48E-04 3.36E-01 2.40E-03 1.68E-02 65 212 "CSMD3,ADORA1,ADORA2A,MTUS1,ANK3,ATP2A2,NRP2,PROM1,BTK,LDB2,CBFA2T2,CHRM1,NRXN1,RAB26,PCYT1B,COL11A2,RTTN,SOCS5,RIMS2,DLX1,DMD,SUGP2,ETV1,DLC1,FGF14,SEMA6C,GPM6A,KLF12,KCNN3,MAP2,MID1,NDP,NEUROD2,NFIA,NOS1,PAX6,PCDH8,PDE4D,GPR85,TMOD2,PIK3CD,PRRX1,NXPH1,PRKCB,SLC6A15,RGS3,SCN3A,MRAS,SH3GL3,CXXC4,TRERF1,SOX5,LMO3,STAC2,TCF4,SATB2,THRA,TLL2,NR2C2,TSC1,PLPPR2,VSNL1,PCDH20,PRDM10,DPF3" Transcription Factor Binding Site V$T3R_Q6 V$T3R_Q6 5.48E-04 3.36E-01 2.40E-03 1.68E-02 65 212 "ABR,SLITRK1,C1QTNF4,OGT,APBB1,IGDCC4,ATP1A2,FGF17,BTK,MTMR3,AP4M1,KCNAB3,NOG,CACNA2D2,CREM,CTNND2,DLX1,NYAP1,USP3,DRP2,GOLGA7,ELAVL2,PIPOX,FGF11,FGF12,SEMA6C,TPPP3,STAG2,RAB30,KDM2B,GP1BB,GRM2,HAPLN2,SYNPO,DHX35,SHISA6,MYLK2,KCNH2,KCNN2,KCNN3,MXI1,MIR4697HG,NFIX,NNAT,PAX6,CDK18,RGS7,SALL1,LRRTM4,SLC8A3,CXXC4,SNCB,SOX5,SPATA7,RAP1GAP2,SMOC1,GSE1,TCF7,TNS2,THRA,TPM1,DNALI1,GAL3ST3,PCBP4,SSPN" Transcription Factor Binding Site V$MEF2_02 V$MEF2_02 6.04E-04 3.71E-01 2.63E-03 1.84E-02 61 197 "NDRG2,ADCY2,CASK,ARNTL,ATP1A2,ADAM23,DIRAS1,CAPN3,USP2,DGKI,MYOM2,NOG,CNTN1,TBPL1,HS3ST5,HAPLN1,SIPA1L1,HDAC9,RHOBTB1,SV2A,DLG2,DMD,ELAVL4,EXTL1,EYA1,CACNG3,FGF12,NBEA,GPR153,GABRB3,ARPP21,MYOZ2,PPARGC1A,ZNF385B,ITGA7,KCNJ9,KCNN1,KTN1,ADAM11,MEF2C,MIR4697HG,NDP,NELL2,RETREG1,RASGEF1B,RASGRF1,RFX4,RGS3,SLC8A3,SLC9A5,CPEB4,SOX5,ARHGAP26,SPTB,FBXW11,SIK3,ITGB3BP,RASD2,TPM2,CELF4,PMEPA1" Transcription Factor Binding Site TTAYRTAA_V$E4BP4_01 TTAYRTAA_V$E4BP4_01 6.25E-04 3.84E-01 2.70E-03 1.89E-02 64 209 "ASIC2,ADRB2,OSBPL6,PPFIA1,BSN,CALM1,SYT6,USP2,DGKI,LARGE1,RAB3C,NDST3,ZFYVE9,SLC24A2,NMT2,CREB5,RGS6,CSNK1E,SPATA2,DMD,DPYSL2,MBNL2,ELAVL4,EPB41,EYA1,CLVS1,FGF14,IP6K2,FUT9,MPP6,GPM6A,IL1RAPL1,HRH3,GABARAPL2,NEGR1,IL6ST,LRRTM3,HECTD2,MPP2,MIR4697HG,NOS1,NPTX1,NPTX2,PCSK2,SERPINE2,PTHLH,ZDHHC14,CRTAC1,FBXW7,SH3GL2,CLSTN1,PREX2,EPN2,FAIM2,FNBP1,POGZ,RGL1,TNS2,RBFOX2,UBE2H,ZBTB14,PRDM8,JMJD1C,JPH3" Transcription Factor Binding Site V$MYCMAX_02 V$MYCMAX_02 6.39E-04 3.92E-01 2.74E-03 1.92E-02 67 221 "CSMD3,ADD3,AMPD2,SEMA7A,B3GALT2,BACH1,CDK5R1,CALB2,SYT6,MAP7,IP6K1,DCT,DLX1,DSCAM,CNNM1,TENM1,EPB41,ETV1,TESK2,FGF14,FOXF2,SYNCRIP,IQGAP2,RAB30,GPR17,ATOH8,BACH2,HPCA,SCRT2,INSM1,MAN2A2,MAT2A,MBNL1,GIT1,NACA,RCOR2,NEUROD2,ENPP2,EPB41L4B,PPP2R2B,RASGEF1B,PRKCG,ANKHD1,FBXW7,FAM192A,SYBU,DZIP1,SLC1A7,KANSL3,SLC12A4,ATF7IP,SOX10,KDM3A,NMNAT2,LMO3,EPB41L3,SEPT3,ADAMTS17,TCF4,SATB2,CBX5,ZFP91,VGF,XPO1,MKRN3,JMJD1C,FXR1" Transcription Factor Binding Site V$NF1_Q6_01 V$NF1_Q6_01 7.27E-04 4.47E-01 3.08E-03 2.16E-02 66 218 "NCKAP5,SLC24A4,GPR158,BCAR3,BBOX1,ALK,MRTFA,B3GALT2,NOL4,JAZF1,CACNA2D1,CLDN10,CBFA2T2,CDH10,CHGA,NRXN2,COL11A2,DCT,SV2A,WDPCP,MBNL2,EIF4G2,RASGRP2,NCALD,PIPOX,FGF11,JPH4,MSTN,NTNG2,RAB30,GLS,STARD3,GPD1,MAP4K5,MYLK2,ZIC5,LRRTM1,KCNH2,MBNL1,MID1,MOV10,MPP2,SESN3,NACA,NFIA,PCDHGC3,PDZRN4,SYTL2,GDPD2,MDGA2,PTH1R,RPE65,SALL1,TRIM46,SLC9A5,SLC15A2,TRERF1,SOX2,ZSWIM8,ANKRD28,SLC35G2,TEK,RBFOX2,ZNF384,STMN4,NAV2" Transcription Factor Binding Site V$OLF1_01 V$OLF1_01 7.27E-04 4.47E-01 3.08E-03 2.16E-02 66 218 "ADCY6,HACE1,PITPNM2,PPFIA2,PPFIA3,ATP1A2,ATP2B3,CACNA1E,SYT6,CCKBR,NOG,CRLF1,COL11A2,C2CD2L,DLG3,HS3ST4,OLIG1,GPR61,ELAVL3,ERCC2,MRVI1,FGF11,FGF12,POLK,FLT1,CYP46A1,GFRA1,GHR,GRIK1,GRIN2D,GRM7,GSTM5,HPSE2,GABARAPL2,IGSF1,KCND1,MEIS2,NEUROD2,NF1,NLGN3,LRRN3,PPP3CB,PRKCG,PSD,PTHLH,RBBP6,RGS3,RLBP1,SCN4B,SMPD3,SGK1,FRMPD1,SLC6A9,EPC1,SOX5,ROBO3,TNS2,TPM1,TRPS1,CA14,UBTF,VGF,DPYSL5,SEMA3B,PCBP4,SLC17A6" Transcription Factor Binding Site V$ZID_01 V$ZID_01 7.77E-04 4.77E-01 3.27E-03 2.29E-02 58 187 "BCAR3,TMEFF1,CHRD,ATP2A2,BCS1L,CDK5R1,BTK,NEURL1,DCLK1,DNAJB5,CNTN1,WHRN,DMD,EPB41,PIPOX,CACNG2,ZIC4,FGFR1,SEMA6C,GDF1,MSTN,GRIK3,MAP4K5,HMGB1,GABARAPL2,TLX1,RBPJ,SCRT2,MBNL1,MEIS2,SESN3,MYH6,NELL2,NFYA,DDR2,ODF2,KCNK10,PAX6,NLGN3,SERPINI1,PLP1,POLG,PPP2R2B,PSD,STX1B,TRIM46,DHX30,SPHKAP,SP4,TCF4,GALNT17,TIAM1,TP53BP1,KCNE5,HIRA,ZIC1,JMJD1C,DPF3" Transcription Factor Binding Site TCCATTKW_UNKNOWN TCCATTKW_UNKNOWN 7.87E-04 4.83E-01 3.29E-03 2.30E-02 59 191 "SEMA6A,BCL7A,BSN,CACNA1D,SLC25A14,CFL2,CHM,CLU,CABP1,CTNND1,CTNND2,MATR3,DLG3,DLX1,DPYSL2,EGR3,ELAVL2,ELAVL4,OLFM1,FGF11,FGF12,FGFR1,IP6K2,SYNCRIP,STAG2,GART,GNAO1,EML4,NR3C1,CELF3,IGF1,IL6ST,MAP2,KITLG,NASP,NCAM2,NNAT,NOS1,OMG,PLXNB1,PPP2R5C,RFX3,LRRTM4,SFPQ,MYO18A,SHANK2,SON,SOX2,SOX5,BEX1,TAB2,TACC1,FBXW11,CLASP1,TEX15,TPM3,NR2C2,VSNL1,NETO1" Transcription Factor Binding Site V$HSF1_01 V$HSF1_01 8.23E-04 5.06E-01 3.42E-03 2.39E-02 64 211 "ACTN2,ADCY6,ADCY8,SLC24A4,PCDH10,UNC79,LINC00173,NOL4,CACNA2D2,PLEKHB1,NRXN3,PPT2,DNAJB5,CREM,SOCS5,GREB1,RIMS2,DBI,DMD,SHANK1,ABCC5,MBNL2,EGR3,PLXNC1,EIF5,ELAVL4,RASGRP2,FHL1,FLNC,GAD1,GAD2,NEK6,GPR17,GRIK1,GRM1,GSN,ELOVL5,SHISA6,SMAD1,MAP2,MOBP,HS6ST3,NNAT,PAK3,PURG,PPP2R2C,PPP2R5C,PTHLH,RFX4,CARF,RORB,RTN1,TNFRSF19,TRERF1,TAB2,FNDC9,ANKRD28,CHST8,TPM2,NR2C2,WRN,ADAMTS9,SCG2,NETO2" Transcription Factor Binding Site V$LBP1_Q6 V$LBP1_Q6 8.47E-04 5.20E-01 3.49E-03 2.44E-02 54 172 "ARID1A,B3GALT2,BCL7A,CACNB2,CAMK2G,SYT6,NEURL1,GPR37L1,CABP1,ZNF385A,SLITRK5,DLG2,MBNL2,EIF4G2,BSCL2,FGR,NBEA,POLL,GRIK3,TMEM25,CELF3,HPSE2,HPCA,USP54,LRRTM3,KCNA2,KCNN3,VWA5A,MYO7A,NOVA1,PCDH9,SPATA6,PPP3CB,PSD,SYTL2,RAB5B,RGR,KCNIP2,RXRG,LRFN5,TRIM46,ATF7IP,SCN3B,SOX5,KIF1B,C11orf87,PHLDB1,VAMP1,DOCK9,CRB1,FNDC5,SLC26A10,GJC2,JMJD1C" Transcription Factor Binding Site YATGNWAAT_V$OCT_C YATGNWAAT_V$OCT_C 8.71E-04 5.35E-01 3.57E-03 2.50E-02 87 304 "EMILIN3,CSMD3,ADORA1,ADORA2A,MTUS1,ALK,ANK3,SEMA7A,MAGEE2,LDB2,CBFA2T2,SYNPR,RAB3C,NRXN3,NRXN1,RAB26,PCYT1B,SNCAIP,HDAC9,DGKG,SCRN1,C2CD2L,DLX1,GRIN3A,RCAN1,PHC2,MBNL2,EML1,ETV1,PIPOX,EYA1,CLVS1,CACNG2,TUBB4A,FGF12,HPCAL4,FOXG1,SEMA6C,SORBS1,DLL3,SALL3,GBX2,GPR22,IL1RAPL1,KCNN3,STMN1,KCTD6,MID1,MMP17,SESN3,NFIA,NKX2-2,NOS1,NPTX2,PAX6,PCDH8,GPR85,CDK14,PLCB2,PDZRN4,PRRX1,NXPH1,POU3F4,SLC6A15,SALL1,LRFN5,MRAS,ITSN1,SH3GL3,ATF7IP,EPC1,TRERF1,SOX5,LMO3,SYT1,ROBO3,TCF4,ARHGEF12,DNAH7,ITGB3BP,THRA,TRPS1,TSC1,PLPPR2,PCDH20,PRDM10,SLC17A7" Transcription Factor Binding Site V$OCT1_04 V$OCT1_04 9.25E-04 5.68E-01 3.76E-03 2.63E-02 61 200 "ANK3,PKP4,CASK,ZBTB10,JAZF1,CACNA1D,SYT6,LDB2,CD86,SYNPR,HDAC9,DLX1,GRIN3A,DMD,ELAVL4,NCALD,ETV1,EYA1,ZIC4,FGF13,FOXG1,TBR1,GABRG1,GABRG2,SALL3,GNAO1,GPM6A,GRIK3,GRM8,MBNL1,MEF2C,MEIS1,MID1,MITF,NCAM1,NDP,NFIA,NFIX,NPTX2,OPCML,PAX6,PBX1,PDE1A,GPR85,PDZRN4,POU3F2,POU3F4,PPP3CB,PRKCB,PTPRD,SOX5,FNBP1,LMO3,RGL1,ZFPM2,THRA,TPD52,ZIC1,ZIC3,PRDM2,SLC17A6" Transcription Factor Binding Site V$DR3_Q4 V$DR3_Q4 9.31E-04 5.72E-01 3.76E-03 2.63E-02 37 108 "ARNTL,ZBTB10,ATP2A2,B3GALT2,TRIM41,CDC27,COL11A2,ZNF385A,DMD,USH1C,ELAVL3,LRRC17,CACNG2,FGR,PRKAG2,MEX3B,NBEA,GGT7,GRM1,TLX1,HPCA,KCNB1,KCNC1,KCNK3,PAX6,EPN1,ARID4A,RBBP6,SALL1,SGK1,LMO3,ERBIN,TMPO,SSBP2,TTC3,XPO1,PCBP4" Transcription Factor Binding Site V$FOXM1_01 V$FOXM1_01 9.38E-04 5.76E-01 3.76E-03 2.63E-02 63 208 "ASIC1,SLITRK1,SLC24A4,MTUS1,MADD,CDH10,CHN2,NRG2,CREB5,PUM1,HDAC9,DLX1,DMD,ELAVL4,FABP7,ATP5PD,FOXG1,IP6K2,SYNCRIP,SALL3,SRCAP,PCDH17,PPARGC1A,PCSK1N,GRM3,HNF4G,KCNA2,KCNJ3,STMN1,LSAMP,MEF2C,MEIS2,MITF,MN1,CTNNA3,MDGA1,NCAM1,NCAM2,NEUROD1,NPTX2,OGG1,OPHN1,P2RX7,PAX6,PCDH9,POU3F4,CEP41,RASGRF1,RGS12,RTKN,SNAP25,SOX5,LMO3,NCDN,CNTN2,TCF12,RALYL,ARHGAP9,VGF,VSNL1,CELF4,RTN4,SLC4A10" Transcription Factor Binding Site V$MZF1_01 V$MZF1_01 1.05E-03 6.47E-01 4.20E-03 2.94E-02 60 197 "ARID1A,NDRG2,ADD3,SEMA6A,ANK2,PHF12,SPTBN4,ARHGAP5,CACNA1D,SYT6,ZNF385A,DLX1,SHANK1,WDPCP,EIF4G1,EIF4G2,RASGRP2,RTN3,FGF11,MEX3B,HPCAL4,FLT1,GABBR1,GAD1,KIAA1841,RAB30,PCDH11X,PRDM5,GRM7,USP54,KCNN3,MEIS2,MGAT3,MN1,MSI1,MXI1,RCOR2,NF1,NFIX,NTRK3,PBX1,PRRX1,NXPH1,PPP2R2B,PPP2R2C,PRKCG,PTPRN,ZDHHC14,GAL3ST4,ZNF532,SALL1,TRIM46,SLITRK3,KANSL3,SCN3B,SPTB,NCDN,CNTN2,XPO1,PCBP4" Transcription Factor Binding Site V$IPF1_Q4 V$IPF1_Q4 1.07E-03 6.59E-01 4.24E-03 2.97E-02 63 209 "SLC24A4,CASK,CBFA2T2,FOXN3,CHM,HAPLN1,RNF14,CTNND2,RHOBTB1,DMD,DYRK1A,KLHL5,TENM1,ELAVL4,CLVS1,ZIC4,EFEMP1,OLFM1,BAIAP2,IP6K2,SYNCRIP,FOXO3,MPP6,ARPP21,SALL3,LPAR4,BACH2,KCNA2,LMO1,SYTL4,MBNL1,MEF2C,MEIS2,NDP,NFIX,OCRL,ZNF827,SNTG1,SLC10A4,GPR85,PLCD1,POU3F4,PPP3CC,RALGDS,RASGRF1,ROM1,SEMA6D,ATF7IP,EPC1,ZHX3,NPAS3,LMO3,TCF12,PCDHGB7,SLC35G2,NR2E1,TNR,ZIC1,ZIC3,CELF4,PMEPA1,PRDM8,DPF3" Transcription Factor Binding Site V$HEB_Q6 V$HEB_Q6 1.08E-03 6.63E-01 4.24E-03 2.97E-02 65 217 "CSMD3,SRPX,ALK,SEMA7A,GAS7,CADPS,NOL4,ADGRB3,BCL2L2,CDK5R2,CACNB2,SYT6,USP2,CBFA2T2,ARHGEF2,GPR37L1,ZNF385A,SPOCK2,DLG2,ELN,SEZ6,RTN3,RASL12,CLVS1,SORBS1,UFM1,TPPP3,NTNG2,POLL,GPD1,GRIK3,ADAMTS8,GRIN2D,LINC01089,CELF3,AGBL5,HPCA,IGF1,GPR62,KCNH2,L1CAM,MYH3,RCOR2,KSR2,PLXNB3,PMP22,PRKCB,MAPK4,PSD,SYTL2,RAB3A,RGS7,RTKN,RXRG,TRIM46,ITSN1,MYO18A,SLC1A7,SOX5,ZSWIM8,CNTN2,ADGRL3,FNDC5,UBTF,USP1" Transcription Factor Binding Site V$AP1_Q2 V$AP1_Q2 1.08E-03 6.65E-01 4.24E-03 2.97E-02 68 229 "AXIN2,ADORA2A,AP2A2,ANXA7,CASK,USP2,NRXN2,MAGED1,CREM,ST18,SCRN1,PITPNC1,AK5,DNM1,HS3ST2,USP3,ARRDC4,EIF4G1,ELAVL2,EPB41L1,RTN3,CLVS1,ZIC4,FGF11,FGF12,BAIAP2,FLNC,DCTN2,RAPGEF6,LYVE1,GSN,MAP4K5,HPSE2,ZNF385B,KCNH2,MAP2,MAP4,MDFI,LRP1B,SHC3,MEIS2,NDP,NEFH,NPY,NTRK2,OMG,KCNK10,PCDH9,PLCD1,MAPK3,PTPRH,PTPRN,ROM1,SLC9A5,SNCB,KDM3A,RAP1GAP2,SRPK2,NCDN,MPRIP,ANKRD28,FBXW11,TCF12,UBE3A,PORCN,ZIC1,PAK5,JMJD1C" Transcription Factor Binding Site TAAYNRNNTCC_UNKNOWN TAAYNRNNTCC_UNKNOWN 1.13E-03 6.95E-01 4.40E-03 3.08E-02 46 143 "ASIC1,ADARB2,SLITRK1,SEMA7A,ARHGAP5,ARRB1,ATP2A2,NOL4,CAMK2A,SYT6,COL11A2,NCOR1,USP3,CERCAM,SEZ6,ZIC4,PPP1R1B,SYNCRIP,FOXO3,GABRA3,GAP43,GPM6A,GRIN2D,KCNH2,KCNJ16,HECTD2,MAP2,MITF,MDGA1,CNOT4,SEMA5B,PLEC,PPARA,LRRN3,SYTL2,RFX2,TNFRSF19,ELMO2,SNAP25,SPATA7,ZNF423,LMO3,ST5,ZFPM2,ITGB3BP,FAM181B" Transcription Factor Binding Site V$TITF1_Q3 V$TITF1_Q3 1.19E-03 7.32E-01 4.60E-03 3.22E-02 58 190 "ASIC2,ASIC1,CSMD3,ADD3,PTBP2,CFL2,CNTN1,CHRDL1,DMD,SHANK1,EGFR,ETV1,EYA1,ZIC4,DACH2,MSTN,PPARGC1A,GNAO1,GPM6A,GRM7,IL1RAPL1,LRRTM1,ITPKB,KCND1,KCNJ3,MARK3,MEF2C,MID1,MXI1,NCAM2,NKX2-2,PAX6,PDGFRA,KCTD15,PPP2R2B,PPP2R5E,CNNM2,SYTL2,PTPRO,ZDHHC14,RFX3,RIT2,KLHL11,ZNF532,RPE65,SATB1,ASIC4,ARX,KANSL3,SLC6A11,CPEB4,SOX5,SRPK2,POGZ,TCF4,NSD1,UBE2H,FIP1L1" Transcription Factor Binding Site V$ATF3_Q6 V$ATF3_Q6 1.22E-03 7.46E-01 4.64E-03 3.24E-02 61 202 "ABR,ADARB2,ADCY8,ADRA1B,PKP4,NOL4,CACNA1G,CDC42,CFL2,CHGB,DNAJB5,SULT4A1,CNN3,CREM,CREB5,PHACTR3,PITPNC1,DCTN1,HS3ST2,MBNL2,PLEKHA1,ING4,OLIG2,AKAP3,ABLIM2,PPARGC1A,RUNDC3A,GLYR1,GPM6B,ADAP1,ELOVL5,ICA1,IGF1,INSM1,KCNN2,MBNL1,ADAM11,MITF,PAK3,ZDHHC8,PNMA3,RPRD1A,TNFRSF19,SLN,SCN3B,ZSWIM8,LMO3,C11orf87,SST,NCDN,GSE1,FBXW11,HHIP,TJP1,NR2E1,DAAM2,RUSC1,UBE2H,ZNF184,SCG2,NUP214" Transcription Factor Binding Site V$CEBP_01 V$CEBP_01 1.23E-03 7.55E-01 4.64E-03 3.24E-02 65 218 "ACLY,NCKAP5,SLC24A4,BCAR3,CASK,ARHGAP5,ARHGEF25,CD86,MAP4K4,CS,HDAC4,DAPK1,SV2B,DMD,CALN1,ARRDC4,EDNRA,PLXNC1,ELAVL2,EYA1,CACNG2,FGF13,IP6K2,NSG2,GCNT2,NR3C1,IL1RAPL1,OPALIN,NIM1K,LRRTM1,KCNK2,LSAMP,MYBPC1,NEUROD1,NKX2-2,PCDH8,PCDH9,PDE3B,PURG,POU3F4,PRKCG,MDGA2,FIGN,RGS3,LRFN5,PPM1E,SLITRK3,CPEB4,RIMS1,SOX2,SOX5,LMO3,SAMSN1,ST5,NCDN,SYNE2,NUDT10,TBL1X,DOCK9,HEY1,C5orf64,TPM1,VSNL1,WRN,PRDM10" Transcription Factor Binding Site V$OCT1_B V$OCT1_B 1.23E-03 7.55E-01 4.64E-03 3.24E-02 67 226 "CSMD3,ADORA1,ADORA2A,ALK,BTK,LDB2,CD86,SYNPR,NRXN3,NRXN1,RAB26,PCYT1B,CSNK1E,HDAC9,DLG2,DMD,ETV1,PIPOX,FGF12,FGF14,HPCAL4,FOXG1,TBR1,GPM6A,KLF12,KCNN3,KCTD6,MID1,MITF,SESN3,MYBPC1,NDP,NFIA,PAX6,PDE4D,TMOD2,PIK3CD,PRRX1,NXPH1,POU3F4,CEP41,PTHLH,SLC6A15,LRRTM4,MRAS,ITSN1,SH3GL3,SLC1A2,ATF7IP,CXXC4,KIF13A,SOX2,ZNF423,LMO3,RGL1,SATB2,TCF12,SLC19A3,THRA,TLL2,NR2C2,TSC1,MGAT5B,PLPPR2,VSNL1,PCDH20,FSTL5" Transcription Factor Binding Site V$LYF1_01 V$LYF1_01 1.23E-03 7.55E-01 4.64E-03 3.24E-02 66 222 "PPFIA2,SHTN1,ASPA,ATP2B3,WASF1,SPAG9,CDC27,NRG2,HAPLN1,DLG2,DMPK,SHANK1,EFNB3,ENO2,RTN3,EYA1,ZIC4,FGF13,IP6K2,ATP2C1,MPP6,STAG2,JPH4,NEK6,MSTN,GFRA1,GLS,GPD1,GPM6A,GRM3,IL1RAPL1,IL11RA,LRRTM3,ITGA7,KCND1,KCNJ10,MEF2C,MEIS1,MSI1,NNAT,NOVA1,NRGN,PDE2A,GPR85,NLGN3,SERPINI1,PLCB2,PLEC,EPB41L4B,MED1,PRKAB2,DPF2,RFX4,CARF,RYR1,TNFRSF19,RPH3A,SOX2,MPRIP,STAC2,SYNE2,TAC3,FBXW11,TCF4,CLASP1,TNNT1" Transcription Factor Binding Site V$HFH3_01 V$HFH3_01 1.26E-03 7.76E-01 4.73E-03 3.31E-02 51 163 "ASIC2,C1QTNF3,PRX,ATP2A2,ADAM23,ADGRB3,SYT6,REPS2,CDH10,LGI1,CSNK1E,DMD,ELAVL4,ETV1,NSG2,IQGAP2,GFRA1,PCDH17,GNAO1,GRIK2,GRM3,KLF12,NKD1,NIM1K,MEF2C,MID1,SCG3,MIR4697HG,NCAM1,NEUROD2,NFIA,NOVA1,PIK3C2A,KCTD15,EPN1,GAL3ST4,SGK1,FBXO11,CPEB4,SOX15,NMNAT2,FBXW11,TCF7L2,TJP1,KAT6B,UBE2H,CELF4,RGMA,NAV3,CAB39L,PHTF2" Transcription Factor Binding Site V$SRY_02 V$SRY_02 1.38E-03 8.50E-01 5.13E-03 3.59E-02 60 199 "KLHL13,LRCH2,B3GALT2,CACNA1E,KYAT1,CBFA2T2,AP4M1,CFL2,CHN1,CASC2,QKI,PUM1,MAML1,RHOBTB1,G3BP2,MBNL2,EIF4G2,ELAVL2,ELAVL4,EN2,OLFM1,SEMA6C,MPP6,STAG2,SALL3,GNAO1,SCRT2,ZNF385B,KCNN2,MITF,MOBP,MDGA1,MXI1,NDP,NFIA,NFIX,NKX2-2,OPCML,PAK3,PIK3R1,PDZRN4,POU3F4,PPP2R2B,PTN,NUDT11,SATB1,TNFRSF19,SOX6,MYO18A,PREX2,SOX2,SOX5,TCF4,TIAM1,HEY1,C5orf64,RBFOX2,ZIC2,KAT6A,CAMK1G" Transcription Factor Binding Site V$OCT1_06 V$OCT1_06 1.40E-03 8.56E-01 5.13E-03 3.59E-02 67 227 "NDRG2,KLHL13,OSBPL6,SEMA6A,ANK3,USP28,PKP4,ZBTB10,SLC4A4,ATP2B1,NOL4,CACNA1D,CARS,LDB2,CBFA2T2,DCLK1,LGI1,FOXN3,CREB5,DLG2,DLX1,ELAVL2,ERBB4,PIPOX,EYA1,FGF12,FGFR3,SEMA6C,DHRS4,GNAO1,GPM6A,STMN2,GRM7,MAP4K5,HNF4G,IGF1,LRRTM3,LMO1,MBNL1,MSR1,NFIA,NPTX2,NTRK3,OMG,PDE4D,MTRF1L,PDZRN4,PMP22,PRRX1,FIGN,KLHL11,FBXW7,SATB1,SCN3A,CHD9,MBD5,TRERF1,SOX5,LMO3,SRPK2,TTBK2,SULF2,SYNE2,PCDHGA1,RALYL,NSD1,CELF4" Transcription Factor Binding Site V$CEBPGAMMA_Q6 V$CEBPGAMMA_Q6 1.40E-03 8.57E-01 5.13E-03 3.59E-02 63 211 "ADARB2,SEMA6A,PPFIA2,BCAS1,NRP2,KALRN,CAMK2G,SPAG9,LDB2,CDK11B,FOXN3,CASC2,HS3ST5,CREB5,CSNK1G3,ST18,DLG2,DLX1,EIF5,ELAVL2,NCALD,EYA1,ACSL4,GABRA1,SALL3,PPARGC1A,GPR22,HNF4G,OPALIN,SHISA6,KCNA1,KCNF1,KIT,LSAMP,MEF2C,MID1,MITF,MN1,RCOR2,NF1,NOVA1,NTRK2,PDGFRA,PCDH18,PDZRN4,PPP3CB,PTK2,PTPRG,RALGDS,RORB,SALL1,SEPHS1,SMARCE1,TRERF1,LMO3,SST,NSD1,ITGB3BP,TMPO,SLC38A1,SCG2,NAV3,JMJD1C" Transcription Factor Binding Site V$MIF1_01 V$MIF1_01 1.44E-03 8.87E-01 5.28E-03 3.69E-02 43 133 "ARID1A,CSMD3,KIAA1324,MADD,PTCH2,BBS2,AP1M1,CARS,CRLF1,CCDC151,MAGED1,TBPL1,DCTN1,C2CD2L,DMD,DNAH9,CPEB2,E2F5,EFNB3,ELAVL2,EMX2,MRPL10,GMPR2,TBC1D16,FGF13,FGR,SDCBP2,GRIK5,GRM3,PACRG,NRGN,RFX2,DHX30,SHANK2,SOX3,SOX5,SPTAN1,NCDN,DNAH7,TP53BP1,CDK20,STMN4,MDH1B" Transcription Factor Binding Site AAANWWTGC_UNKNOWN AAANWWTGC_UNKNOWN 1.49E-03 9.14E-01 5.41E-03 3.78E-02 52 168 "SPARCL1,ANK2,ANK3,PPFIA2,APP,ASPA,CACNA1D,CALM1,SPAG9,FOXN3,DNAJB5,CNTFR,SNCAIP,DLG2,DMD,DSCAM,ELAVL4,OLIG2,CACNG3,OLFM1,SEMA6C,SALL3,NEK6,PPARGC1A,KLF12,LSAMP,MAN2A2,MBNL1,SHC3,MEF2C,MEIS1,MID1,NFE2L2,NNAT,NTRK3,OMG,ZNF827,PAX6,PCSK1,PPP3CC,MAPK3,PRIMA1,FBXW7,SOX5,ZHX3,C11orf87,ADHFE1,KANK1,GANAB,SATB2,DPYSL5,ITM2C" Transcription Factor Binding Site V$CDP_02 V$CDP_02 1.51E-03 9.26E-01 5.45E-03 3.81E-02 32 92 "SEMA6A,LRCH2,NRXN3,CS,PHACTR3,DOCK4,DGKB,STAG2,GBX2,GNAO1,GPM6A,IL1RAPL1,HNF4G,LSAMP,MBNL1,MEF2C,MEIS1,PPM1L,HCN1,OGG1,SEMA5B,PDZRN4,POU3F4,CARF,SALL1,SLC1A3,SLC6A9,CPEB4,KIF1B,SRPK2,SYT1,TCF4" Transcription Factor Binding Site V$TCF11_01 V$TCF11_01 1.56E-03 9.58E-01 5.53E-03 3.87E-02 57 188 "NCKAP5,KIAA1324,SPARCL1,PI16,ZNF582,BTK,SPAG9,CFL2,SYNPR,PCYT1B,COL9A1,MAGED1,CREB5,RIMS2,AK5,WDR20,DLG2,DMD,HS3ST2,ECM2,MBNL2,CACNG2,ZIC4,CAMSAP1,UBE2E3,SORBS1,STAG2,GRIA1,GRIK3,SHISA6,LRRTM3,ITGAM,KCNA1,HECTD2,MAP2,MAPT,MITF,MYT1,NTRK3,PCSK5,PCSK2,PDE4D,POU3F4,LRRTM4,SLC4A3,EFHD1,CPEB4,SMARCD3,ZSWIM8,KIF1B,SRPK2,CNTN2,SATB2,TNR,KCNK12,FBXO36,JMJD1C" Transcription Factor Binding Site V$MYB_Q3 V$MYB_Q3 1.56E-03 9.58E-01 5.53E-03 3.87E-02 57 188 "ASIC2,SEMA7A,PPP4R4,CASK,B3GALT2,CACNA1G,CAMK2A,CANX,SPAG9,DGKI,CHGA,NRXN3,ARHGEF6,SPOCK2,DMD,DSCAM,PLXNC1,GOLGA7,BSCL2,EPB41,GPHN,GMPR2,FGF12,FOXF2,CELF1,MYOZ2,PCSK1N,GNAS,GNG3,KLF12,IL11RA,CDH20,LIG4,MAP4,NOVA1,NRGN,HCN1,ODF2,OMG,OPCML,PCDH9,ING3,MDGA2,FIGN,RFX3,RASA3,RIMS1,SCN3B,SOX5,ANKRD28,TRIM2,SSBP2,UBE2H,UBE3A,VAV1,XPO1,GAN" Transcription Factor Binding Site V$AP1FJ_Q2 V$AP1FJ_Q2 1.57E-03 9.62E-01 5.53E-03 3.87E-02 69 236 "AXIN2,ANXA7,CASK,SPTBN4,USP2,NRXN2,DNAJB5,RGS6,ST18,SCRN1,PITPNC1,SV2A,AK5,DNM1,HS3ST2,USP3,ARRDC4,EEF1A2,EIF4G1,EPB41L1,RTN3,CACNG2,FGF11,FGF12,FLNC,GABBR1,GABRA1,RAPGEF6,LYVE1,RUNDC3A,GRIN2D,GSN,ATOH8,HPSE2,SYNPO,ZNF385B,MAP2,MAP4,MDFI,LRP1B,SHC3,MEIS2,NDP,NPY,NTRK2,OMG,KCNK10,PCDH9,PLCD1,MAPK3,PTPRH,PTPRN,ROM1,SLC6A9,SLC9A5,SNCB,TSNAXIP1,KDM3A,NCDN,MPRIP,FBXW11,TCF12,UBE3A,FLRT1,VGF,PORCN,ZNF23,RTN4,JMJD1C" Transcription Factor Binding Site V$GCM_Q2 V$GCM_Q2 1.57E-03 9.63E-01 5.53E-03 3.87E-02 58 192 "ARID1A,ADD3,ADRA1B,SPOP,AMPD2,MAP4K3,SPTBN4,B3GALT2,NOL4,ADGRB3,CACNA1G,KALRN,CAST,LGI1,DNAJB5,MAGED1,NRG2,SLITRK5,DCT,SEMA3D,EMX2,FGF11,MPP6,STAG2,GAP43,GDF1,LOXL3,GNAO1,GNAS,GRIA1,TMEM25,KAT7,KLF12,RBPJ,LRRTM1,KCNB1,MBNL1,MITF,SESN3,NEUROD1,NTRK2,NLGN3,EPB41L4B,RASGEF1B,CNNM2,PSD,RASGRF1,SLC12A4,SCMH1,SRPK2,TBL1X,RALYL,THRA,HEY1,NR2E1,TPM2,ZNF32,PCBP4" Transcription Factor Binding Site CAGNYGKNAAA_UNKNOWN CAGNYGKNAAA_UNKNOWN 1.79E-03 1.00E+00 6.22E-03 4.35E-02 22 57 "EMILIN3,ATP1A2,CBFA2T2,CACNA2D2,RHOBTB1,SYNCRIP,GABRB3,GAD2,GFRA1,GRIK3,NR3C1,SYTL4,HECTD2,NKX2-2,NNAT,PDE4D,TNFRSF19,MYO18A,DHX30,WDTC1,CLSTN2,TBL1X" Transcription Factor Binding Site V$CREBP1CJUN_01 V$CREBP1CJUN_01 1.80E-03 1.00E+00 6.22E-03 4.35E-02 63 213 "SLC25A25,ADCY8,PKP4,ALS2,MADD,B3GALT2,NOL4,CAMK2D,SPAG9,KYAT1,SYNGR3,CHGB,CLCN3,SULT4A1,CREM,SEC24C,PHACTR3,KCTD8,DCTN1,PARD6A,G3BP2,HS3ST2,RCAN1,MBNL2,ING4,EPB41,NCALD,DNAJC27,SYNCRIP,ZMYND15,FLT1,PPARGC1A,RUNDC3A,GPM6B,ADAP1,ELOVL5,KCNF1,ZFYVE27,SCAMP5,MITF,NCAM1,NF1,OGDH,PCSK1,PNMA3,MAPK10,RPRD1A,SNAP25,SPATA7,C11orf87,SST,SYT11,HHIP,NR2E1,DAAM2,TRPC1,RUSC1,UBE2H,VGF,ZNF184,SLC38A1,SCG2,NUP214" Transcription Factor Binding Site V$AP1_Q6_01 V$AP1_Q6_01 1.80E-03 1.00E+00 6.22E-03 4.35E-02 63 213 "CSMD3,AXIN2,AP2A2,ANK3,ANXA7,CASK,BTK,DCLK1,ZFYVE9,MAGED1,SNPH,SCRN1,GIT2,PITPNC1,SV2A,AK5,DMPK,DYRK1A,EEF1A2,EIF4G1,ELAVL2,EPB41L1,RCAN2,EYA1,FLNC,DCTN2,GABBR1,MYOZ2,RAB30,GRIA1,MAP4K5,RBPJ,ZNF385B,KCNA2,KCNH2,MAP2,MAP4,MDFI,LRP1B,GIT1,NDP,OLR1,OMG,KCNK10,PCDH9,SNX10,PPP2R2C,MAPK3,PTPRH,NUDT11,SGK1,SLC11A1,RIMS1,SNAP25,KDM3A,RAP1GAP2,SRPK2,MPRIP,NUDT10,SYN1,FBXW11,UBE3A,VGF" Transcription Factor Binding Site V$CDX2_Q5 V$CDX2_Q5 1.80E-03 1.00E+00 6.22E-03 4.35E-02 61 205 "NCKAP5,NDRG3,ZBTB10,BTK,RGN,CBFA2T2,CFL2,CASC2,NRXN1,CLTC,CPS1,CREB5,NCOR1,RIMS2,DLX1,DMD,ECM2,MBNL2,ELAVL2,ELAVL4,SEZ6,ZIC4,GAD1,PPARGC1A,GRIK3,IL1RAPL1,BACH2,HECTD2,LSAMP,SMAD1,MBNL1,ADAM11,MEIS1,MEIS2,MN1,PAX6,PCSK1,PCSK2,KCTD15,PDZRN4,PRPH,SYTL2,PTH1R,CYB561D1,ROBO1,RPE65,RPL38,ARX,SNAP25,MBD5,TRERF1,LMO3,SRPK2,TRIM2,RALYL,ZFPM2,AMOT,VLDLR,NAV3,PLSCR4,DPF3" Transcription Factor Binding Site YYCATTCAWW_UNKNOWN YYCATTCAWW_UNKNOWN 1.92E-03 1.00E+00 6.58E-03 4.60E-02 49 158 "DPF1,ASIC2,CDC7,AP1B1,ANK3,CASK,BMP7,WASF1,CALM1,DCLK1,CLTC,DNAJB5,CPS1,DLX1,DMD,DNM1L,ERBB4,FGFR3,FOXG1,FYN,GABRA1,SALL3,GAP43,RAB30,GPM6A,KLF12,SHISA6,RBPJ,SCG3,MXI1,MYO9A,NFIA,DDR2,PDE4B,CCSER2,PLCB2,LAMA1,RFX4,RGS3,EMID1,SCN3A,ATF7IP,SMARCA4,SP4,TPM3,TSC1,XPO1,LRP8,SCG2" Transcription Factor Binding Site V$ERR1_Q2 V$ERR1_Q2 2.05E-03 1.00E+00 6.83E-03 4.78E-02 62 210 "ABAT,NDRG2,SORCS1,FZD9,SEMA7A,APP,CACNB2,DIRAS1,SPAG9,NOG,LHX2,RIMS4,KIAA0586,DLG2,ABCC5,ELAVL3,RASGRP2,CDHR1,DLC1,KIRREL3,GK,HTATSF1,GRIK3,PSIP1,KCNH2,KCNK1,KCNN1,KIF5A,HECTD2,MEF2C,MYL3,SNTG1,RAB3A,RFX5,RGS4,RYR3,SATB1,PPM1E,RPH3A,URGCP,SMARCC2,UNC5B,LMO3,SRPK2,MPRIP,STAC2,VAMP1,ANKRD28,SLC37A2,CNTN2,TCF7,THRA,NR2C2,UCHL1,PLPPR2,TBC1D15,VSNL1,SLC30A3,PCBP4,KAT6A,JMJD1C,SOCS4" Transcription Factor Binding Site V$MEF2_03 V$MEF2_03 2.05E-03 1.00E+00 6.83E-03 4.78E-02 59 198 "NDRG2,ADCY2,SEMA7A,CASK,ARNTL,ATP1A2,DIRAS1,CAPN3,USP2,DGKI,CNTN1,HAPLN1,NCOR1,SIPA1L1,CTNND2,HDAC9,SV2A,DLG2,DMD,MBNL2,ELAVL4,EXTL1,EYA1,FGF12,NBEA,ARPP21,MYOZ2,PPARGC1A,ZNF385B,ITGA7,KCNJ9,KCNN1,KTN1,ADAM11,MEF2C,MGAT3,MIR4697HG,NDP,GPR85,PRRX1,RASGEF1B,PTPRO,RASGRF1,RFX4,YJEFN3,LRRTM4,FBXO11,SLC8A3,SHANK2,EFHD1,CPEB4,SOX5,ARHGAP26,FBXW11,TPM2,CELF4,PMEPA1,GAL3ST3,SSPN" Transcription Factor Binding Site V$AFP1_Q6 V$AFP1_Q6 2.05E-03 1.00E+00 6.83E-03 4.78E-02 61 206 "DSCAML1,C1QTNF3,PKP4,ARNTL,LINC00173,SLC4A4,JAZF1,NOG,MAP4K4,HS3ST5,CREB5,CNTNAP2,CHRDL1,DLX1,DMPK,DPYSL2,EGFR,TENM1,ELAVL2,ING4,ZIC4,EFEMP1,FGF12,FOXF2,TBR1,KIRREL3,IL1RAPL1,HAS2,LRRTM3,KCNMA1,KCNN3,MAP4,MBD1,ADAM11,MEIS2,MYBPC1,NKX2-2,PCDHGC3,PCSK2,PDGFRA,KCTD15,PDZRN4,PRRX1,PROX1,LRFN5,TRERF1,SPATA7,SP4,SPTB,EPB41L3,SULF2,ANKRD28,SATB2,PUM2,TEX15,ZFPM2,RBFOX2,WNT7A,ZIC1,WNK1,JPH3" Transcription Factor Binding Site V$DR4_Q2 V$DR4_Q2 2.05E-03 1.00E+00 6.83E-03 4.78E-02 61 206 "ADD3,PHF12,APOC1,RASL11B,ATP1A2,ASIC3,NDST3,MAP4K4,COL11A2,ZNF385A,ABCG1,ARHGAP24,HDAC4,DLG2,DLX1,DMD,EDN1,OPTN,EIF4G1,ELAVL2,PLEKHA1,ELAVL4,ENO2,RASGRP2,EYA1,PTK2B,FGF11,IP6K2,SEMA6C,CAMKK2,STAG2,GAD1,GART,PCSK1N,HRH3,HMGB1,KCND3,PIK3AP1,MEIS2,MITF,MOV10,MYH6,NELL2,NNAT,NOVA1,NPTX2,NLGN3,ACER3,SGK1,SLC1A7,SON,SOX5,SOX15,SPTB,STAC2,PUM2,NR2E1,STXBP4,UBE2H,ZIC2,ZNF213" Transcription Factor Binding Site V$AP2_Q6_01 V$AP2_Q6_01 2.05E-03 1.00E+00 6.83E-03 4.78E-02 61 206 "KCNH8,ASIC2,ARID1A,UNC79,APLP1,ASCL1,KCNAB3,LHX2,DBN1,DLG3,DMPK,NYAP1,DTNB,EFNB3,EGR3,PLXNC1,EIF4G2,CERCAM,RASGRP2,EPHB1,EYA1,FGF11,ATP5PD,TACC2,CGREF1,OGA,MSTN,GP1BB,GPR12,CLASRP,TMEM25,NXPH3,ITPKA,KCNH2,KCNK3,STMN1,MN1,PFKFB3,FXYD1,SPATA6,RAP1GDS1,CYB561D1,SALL1,LRFN5,PPM1E,CPEB3,SLC6A11,SLC12A4,SOX2,FNBP1,TAB2,CAMTA2,RALYL,HEY1,NR2E1,TUBA3FP,UBTF,PORCN,RGMA,SLC17A7,ST7" Transcription Factor Binding Site YKACATTT_UNKNOWN YKACATTT_UNKNOWN 2.28E-03 1.00E+00 7.56E-03 5.29E-02 66 227 "ADD3,ARNTL,ATP2B3,ZNF582,ADGRB2,FOXN3,CASC2,KMT2C,CLU,RGS6,MICAL2,ARHGAP24,PITPNC1,ELMO1,DMD,EFEMP1,DLC1,POLR1B,FGF13,OGA,RAPGEF6,GBX2,MSTN,GDF9,DHRS4,GLYR1,PCDH11X,NR3C1,KLF12,HAPLN2,ZNF546,IGF1,INSM1,LIMS1,ARHGAP12,LRP1B,MEF2C,MEIS1,GIT1,STK32C,ADAM22,DDX25,PDGFRA,PIK3R1,PDZRN4,PPP2R2B,MAPK10,PTPRD,PYGM,RAP1GDS1,RBBP6,DPF2,PRR5L,ZNF568,LRFN5,SMPD3,LMO3,SS18,FGD4,SYNE2,DNAH7,AMOT,ZNF189,FTSJ1,SNX14,DPF3" Transcription Factor Binding Site V$NF1_Q6 V$NF1_Q6 2.29E-03 1.00E+00 7.56E-03 5.29E-02 65 223 "ADORA1,SLC24A4,ALK,CHRD,B3GALT2,NOL4,FGF17,JAZF1,CALM1,CLDN10,CBFA2T2,CHGA,NRXN2,COL11A2,DCT,DLG3,WDPCP,MBNL2,PIPOX,FGF11,JPH4,NTNG2,STARD3,MYLK2,IL11RA,LRRTM1,KCNH2,MBNL1,MEF2C,MID1,MOV10,MPP2,SESN3,RCOR2,NFIA,NKX2-2,NTRK3,PCDHGC3,NLGN3,PDZRN4,MAGEL2,SYTL2,GDPD2,MDGA2,PTH1R,RPE65,SALL1,TRIM46,BTBD3,SLC15A2,SOX2,ZNF423,CAMTA2,GSE1,ANKRD28,SLC35G2,TEK,HEY1,RBFOX2,ZNF384,SSBP2,STMN4,NAV2,HRASLS,SLC4A10" Transcription Factor Binding Site V$ARNT_01 V$ARNT_01 2.61E-03 1.00E+00 8.55E-03 5.99E-02 63 216 "MTUS1,AMPD2,ZBTB10,SYT6,MAP7,AKAP12,CRY2,TBC1D5,KIAA0586,COPS7A,DSCAM,CNNM1,CELSR3,ELAVL3,DCTN4,ETV1,TESK2,PPP1R1B,FGF14,FOXF2,SYNCRIP,SYT3,GK,TCERG1,HPS5,SCRT2,STMN1,MBNL1,FXYD6,RCOR2,NEUROD1,NEUROD2,SLCO1C1,NKX2-2,NPTX1,PAX6,EPB41L4B,ANKHD1,RAB3IL1,RBBP6,PBRM1,FAM192A,ATF7IP,CPEB4,EPC1,OGDHL,SNAP25,NMNAT2,TAC1,ANKRD12,WASHC4,RALYL,SIRT1,CBX5,ZFP91,CA14,HIRA,VGF,VLDLR,TBC1D15,XPO1,RTN4,KAT6A" Transcription Factor Binding Site V$E2F1_Q3_01 V$E2F1_Q3_01 2.64E-03 1.00E+00 8.59E-03 6.01E-02 59 200 "AXIN2,SLC12A5,AK2,PHF12,CPNE5,ARNTL,ADAM23,CALM1,SYT6,USP2,AP4M1,DCLK1,LHX2,ZNF521,NRG2,MAML1,SPOCK2,DMD,ABI2,EGR3,EIF4G1,EIF5,ELAVL4,FGF11,FGF13,SYNCRIP,FOXO3,TPK1,STAG2,NKX6-2,TMEM25,INSM1,ITPKA,KCNA1,KCND3,STMN1,MEIS1,MEIS2,MSI1,NCAM1,NEUROD2,NRGN,RELN,ZCWPW1,KLHL11,SATB1,PUF60,ARX,SLITRK3,ELMO2,TTC17,DNAJC9,SATB2,ARHGEF12,NR2E1,RASD2,TRPS1,CELF4,LRP8" Transcription Factor Binding Site V$CREBP1_Q2 V$CREBP1_Q2 2.64E-03 1.00E+00 8.59E-03 6.01E-02 58 196 "ABR,SLC25A25,BIN1,NOL4,KYAT1,USP2,SYNGR3,CHGB,CREM,KCTD8,DMD,HS3ST2,RCAN1,EGR3,NCALD,DNAJC27,FGF13,ZMYND15,FLT1,PPARGC1A,RUNDC3A,GK,GLYR1,GNAS,GNG4,GPM6B,GRM3,ELOVL5,ICA1,KCNK1,SMAD1,MBNL1,SCAMP5,NAP1L2,NF1,NPTX1,PCSK1,PDE4D,PNMA3,ING3,RBBP8,RET,RPRD1A,SNAP25,C11orf87,TACR1,HHIP,THRA,NR2E1,DAAM2,TPM4,RUSC1,BCL2L13,VGF,SPHK2,ZNF184,SCG2,NUP214" Transcription Factor Binding Site GGATTA_V$PITX2_Q2 GGATTA_V$PITX2_Q2 2.76E-03 1.00E+00 8.91E-03 6.24E-02 127 484 "EMILIN3,CSMD3,ADD3,SLC12A5,ADORA1,GPR158,SEMA6A,CDC42BPA,EPB41L5,PRX,ASPA,SYNJ1,CAMK2A,SLC25A14,LGI1,NOG,SYNPR,NDST3,SLC22A6,CNTFR,PCYT1B,SLC4A7,ZNF385A,CLOCK,CREM,CREB5,SNCAIP,SIPA1L1,SLITRK5,PPP1R16B,DCT,ELMO1,C2CD2L,DLG4,DMD,DNM1,DMPK,PHC2,MBNL2,TENM1,NCALD,EFS,RTN3,EYA1,EFEMP1,FGFR3,HPCAL4,FOXF2,IP6K2,TBR1,GABRA1,GAD1,ARFIP1,GK,GLI2,GOLGB1,GPM6B,PLCD4,IL1RAPL1,HMGB1,HSF2,USP54,INSM1,KTN1,LIFR,LMO1,MAP2,KITLG,MID1,MITF,DDX25,CTNNA3,MYBPC1,MYH6,NACA,NEUROD2,NOVA1,NTRK2,DDR2,PBX1,PCSK1,PDE1A,PDE4B,KCTD15,PRRX1,PPM1B,PPP3CA,MAPK9,PSD,SYTL2,SLC6A15,FIGN,RFX4,RGR,RLBP1,ROBO1,RXRG,SCN3A,ITSN1,ARX,FBXO11,SLITRK3,DHX30,CPEB4,SOX15,SP4,ARHGAP26,LMO3,ANKRD28,MTCL1,ROBO3,TCF4,TCF7,AHCYL2,DNAH7,NR2E1,TPM2,TRPS1,UBTF,PRDM8,PRDM10,NAV3,PCBP4,FBXO36,CAMK1G,JMJD1C,SLC39A12" Transcription Factor Binding Site V$AP1_Q2_01 V$AP1_Q2_01 2.85E-03 1.00E+00 9.18E-03 6.42E-02 67 233 "NDRG2,ADCY8,AXIN2,ADORA2A,GPR158,ANK3,ADAM15,DIRAS1,P2RX6,CHRM1,BRINP1,C2CD2L,DLG4,USP3,DUSP9,DYRK1A,EIF4G1,ELAVL2,ELAVL4,ENO2,EPB41L1,RTN3,EYA1,TUBB4A,FLNC,MYOZ2,GFAP,RUNDC3A,RAB30,PCSK1N,KLF12,HPSE2,RBPJ,ZNF385B,KCNH2,SFXN5,MITF,DDR2,OLR1,OMG,KCNK10,PCDH9,NLGN3,SNX10,PLCD1,PPP2R2C,PTPRH,PTPRN,RPS20,TRIM46,SHANK2,RIMS1,SNCB,KDM3A,RAP1GAP2,NCDN,GSE1,SYP,COBL,TAC1,TCF4,TCF12,TUBA3FP,UBE3A,SLC30A3,SEMA3B,RTN4" Transcription Factor Binding Site V$HMX1_01 V$HMX1_01 2.88E-03 1.00E+00 9.20E-03 6.44E-02 15 35 "SLITRK1,AMPH,PHF12,BCL2L2,CACNB2,CBLN1,FGF12,PTPRT,KCNN1,NKX2-2,OMG,PBX1,TNPO2,TRERF1,DAAM2" Transcription Factor Binding Site V$RORA2_01 V$RORA2_01 2.94E-03 1.00E+00 9.22E-03 6.45E-02 39 122 "TTYH1,ABAT,CSMD3,C1QTNF3,C1QTNF4,ARNTL,ASPH,B3GALT2,CACNA1A,KCNAB3,KMT2C,NMT2,CLOCK,CTH,HDAC9,NTM,CHRDL1,DMD,ATP5PD,CAMKK2,OGA,GLYR1,GRIA1,HPCA,LMO1,MEIS2,MPP2,KCTD15,PYGM,KHDRBS2,RYR1,SH3GL2,SLA,SPTAN1,TTBK2,SYNE1,TMEFF2,PCBP4,JMJD1C" Transcription Factor Binding Site V$CEBP_C V$CEBP_C 2.96E-03 1.00E+00 9.22E-03 6.45E-02 50 165 "ADRB2,SLC24A4,OSBPL6,SEMA7A,APC,USP2,MAP4K4,CREB5,BOC,HDAC9,DLG2,DLX1,DMD,MBNL2,SEZ6,ETV1,CACNG2,ZIC4,FGF12,FGF14,FOXO3,STAG2,MSL3,IL1RAPL1,CELF3,SHISA6,LRRTM3,LRRTM1,KCNMA1,MEIS1,MITF,NEUROD1,DDR2,NUMA1,P2RY1,PDE4D,PDGFRA,PIK3C2A,PIK3R1,PLCB2,ING3,PROX1,PTAFR,RFX4,FBXW7,SARS,LMO3,BCL2L13,ZIC1,JMJD1C" Transcription Factor Binding Site V$FOXO4_02 V$FOXO4_02 2.98E-03 1.00E+00 9.22E-03 6.45E-02 60 205 "BCL7A,CACNA2D1,AP4M1,CFL2,CASC2,ZFYVE9,CNR1,ZNF521,SNCAIP,DOCK4,PITPNC1,USP3,EIF4G2,ELAVL2,EML1,EZH1,FGF12,FLNC,MPP6,STAG2,SALL3,ARFIP1,GFRA1,BRD8,GNAO1,GNAS,NR3C1,IL1RAPL1,HAS2,NXPH3,KLF12,IL6ST,SMAD1,MEIS2,MDGA1,NFIX,NNAT,NTRK3,ZNF827,PALM,ENPP2,PCDH18,PDZRN4,RASGEF1B,MAPK10,ARID4A,RFX3,SCN3A,SH3GL3,TRERF1,KDM3A,NPAS3,LMO3,APOM,SATB2,TEK,THRA,TIAM1,UBE2H,JPH3" Transcription Factor Binding Site V$FAC1_01 V$FAC1_01 2.98E-03 1.00E+00 9.22E-03 6.45E-02 51 169 "SRPX,LRCH2,APC,TMEFF1,NRP2,MTMR3,CACNA1G,CACNA1D,REPS2,CHM,NRXN3,MAP4K4,HDAC9,DMTF1,EPS8,EYA1,ZIC4,FGF12,STAG2,SALL3,GNAS,GRIK3,IL1RAPL1,MAP4K5,HAS2,GABARAPL2,IGF1,NKD1,KCNC2,KCNMA1,MSRA,NEUROD2,NFIX,NKX2-2,CNOT4,NTRK2,CCSER2,ZCWPW1,RBBP6,PBRM1,ROBO1,SGK1,FBXO11,SOX5,LMO3,ADGRL3,TCF7L2,HEY1,ZIC1,DNALI1,NAV3" Transcription Factor Binding Site YRTCANNRCGC_UNKNOWN YRTCANNRCGC_UNKNOWN 2.98E-03 1.00E+00 9.22E-03 6.45E-02 20 52 "SULT4A1,PARD6A,DPYSL2,FLNC,GNAO1,GPM6B,GRM7,ELOVL5,NCAM1,PFKFB3,RASGRF1,SLC6A15,TRIM46,NCDN,TACC1,NR2E1,UBE2H,UCHL1,PITPNB,SMARCAD1" Transcription Factor Binding Site V$PBX1_01 V$PBX1_01 2.99E-03 1.00E+00 9.22E-03 6.45E-02 59 201 "AXIN2,PCDH10,BMPR1B,CAMK2D,CBLN1,COL4A5,FEZ1,PHACTR3,HDAC9,DLG2,DLX1,ELAVL2,EMX2,ERBB4,MRVI1,ZIC4,FGF13,IP6K2,TBR1,IL1RAPL1,ADAMTS6,HNF4G,STMN1,MBNL1,SHC3,PPM1L,MITF,MYT1,NAP1L2,NDP,KCTD15,PDZRN4,SCHIP1,PPP3CB,ZNF532,SALL1,SCN7A,SOX6,FBXO11,PREX2,SMTN,SLC6A9,TRERF1,SSTR1,STAC2,SYT1,SYT4,ROBO3,TBL1X,TCF7,RALYL,ZFPM2,RBFOX2,ZIC1,ZIC2,CELF4,PRDM8,SLC17A6,CAMK1G" Transcription Factor Binding Site V$ZF5_01 V$ZF5_01 3.00E-03 1.00E+00 9.22E-03 6.45E-02 57 193 "ASIC1,DSCAML1,SEMA7A,PHF12,APBB1,BCL7A,ARHGEF7,BTRC,CACNA1A,CALM1,SPAG9,NEURL1,DCLK1,HOMER3,ZNF521,CDC42BPB,DNM2,PHC2,PLXNC1,ELAVL3,SEZ6,MEX3B,GFER,KIRREL3,GRIK3,TLX1,HPCA,ITPKA,KCNC1,KCND3,STMN1,MSI1,HS6ST3,TMOD2,KCTD15,TNPO2,RASGRF1,ARID4A,RGS7,PRIMA1,SALL1,LRFN5,SMPD3,SEC14L1,SORCS3,KIF1B,ABCC8,TAL1,ARHGEF12,TPM1,UBTF,KLC2,ZIC2,CELF4,CA10,LRP8,FAM13C" Transcription Factor Binding Site V$CACBINDINGPROTEIN_Q6 V$CACBINDINGPROTEIN_Q6 3.00E-03 1.00E+00 9.22E-03 6.45E-02 57 193 "DPF1,ADRA1D,MRTFA,ARHGAP5,NOL4,BCL7A,CACNA1G,CACNA1D,SYT6,CHRM1,ZNF521,ZNF385A,PHACTR3,PYGO1,DCTN1,DLX1,DMD,EFNB3,EIF4G1,EMX2,RTN3,CACNG2,FGF11,HPCAL4,DCTN2,TPPP3,CHL1,JPH4,GNAO1,AP4S1,NXPH3,NEGR1,KCNN3,MGAT3,NCAM1,RCOR2,NEUROD2,NFIX,NRGN,PBX1,STRN3,PRRX1,PKIA,PRKCG,PSD,GDPD2,EMID1,FAM192A,SALL1,LRFN5,TRIM46,EPC1,NCDN,ARHGEF12,VGF,ADAMTS9,FBXO36" Transcription Factor Binding Site V$IRF1_Q6 V$IRF1_Q6 3.30E-03 1.00E+00 1.00E-02 7.03E-02 63 218 "ADORA3,DPP10,ARHGAP5,ASPA,STX16,ATP2B1,B3GALT2,ADAM23,ADAM15,NRXN3,QKI,LY86,COL9A1,TOGARAM2,ZNF385A,SIPA1L1,CTNND2,DLG2,DLX1,DYRK1A,PLXNC1,ELAVL4,EMX2,TUBD1,ENPP6,EPS8,ERBB2,FGF12,FOXG1,SORBS1,ATP2C1,MEGF11,PPARGC1A,KIF3A,SCRT2,MBNL1,MEF2C,MITF,MYL3,NCAM2,CNOT4,PAX6,PCDHGC3,PCDH9,SERPINI1,SEMA5B,PDZRN4,PRKCB,PROX1,MDGA2,RET,FIGN,TRAPPC13,TNFRSF19,SGK1,EPN2,NAPB,TTC17,SOX11,SYNE2,SIK3,TMPRSS5,NETO1" Transcription Factor Binding Site YTAATTAA_V$LHX3_01 YTAATTAA_V$LHX3_01 3.30E-03 1.00E+00 1.00E-02 7.03E-02 46 150 "ADD3,OSBPL8,ARNTL,LDB2,CDH10,SLC24A2,PITPNC1,ELMO1,DMD,CALN1,DLC1,PPP1R1B,TBR1,SALL3,GNAO1,LRRTM1,KCNK2,MBNL1,ADAM11,MID1,MYT1,NFYA,NOVA1,SEMA5B,KCTD15,PDZRN4,PRRX1,FIGN,RORB,LRFN5,PPM1E,ZNF423,LMO3,SRPK2,LRRC4,SULF2,TAL1,CHST8,HHIP,KAT6B,SEZ6L,WNT7A,PRDM8,FIP1L1,ADAMTS10,SSPN" Transcription Factor Binding Site RRAGTTGT_UNKNOWN RRAGTTGT_UNKNOWN 3.39E-03 1.00E+00 1.02E-02 7.13E-02 58 198 "ASIC1,CSMD3,LRCH2,GAS7,APP,SPAG9,LGI1,FOXN3,CNR1,ZNF521,CREB5,CNTNAP2,SLITRK5,RASSF2,DLG3,DMD,EDIL3,ERBB2,NCALD,ETV1,ZIC4,POLK,SYNCRIP,GABRA1,GABRA3,ZNF274,GHR,RAB30,MSL3,SCRT2,KCNA1,KCND2,MBNL1,SESN3,NKX2-2,ZDHHC22,PAX6,PIK3R1,ING3,RELN,PTPRG,ZDHHC14,CRTAC1,ITSN1,BTBD3,DHX30,RIMS1,SOX2,SOX11,C11orf87,TCF4,HHIP,TLL2,DAAM2,ZNF32,CELF4,ZNF189,SNX27" Transcription Factor Binding Site V$AR_Q6 V$AR_Q6 3.40E-03 1.00E+00 1.02E-02 7.13E-02 57 194 "SLC25A25,CSMD3,CASK,BMP7,BTK,LDB2,SLC22A6,NRXN3,NRG2,ATRNL1,HDAC9,SPATA2,ELMO1,KLHL3,DMD,SGK2,ELAVL2,SEZ6,CAMSAP1,IP6K2,SYNCRIP,NBEA,RAPGEF6,GAP43,MSTN,PPARGC1A,GK,USP54,LMO1,SMAD1,MAP4,MBNL1,MEF2C,MID1,SESN3,NKX2-2,NNAT,PCDH9,PDYN,GDAP1L1,EPN1,MTRF1L,EPB41L4B,FA2H,PPP2R2B,MAPK3,RBBP6,PBRM1,SCN3B,ARHGAP26,SMOC1,TBL1X,PUM2,SIK3,TEK,TPM3,TOM1L2" Transcription Factor Binding Site V$TCF11MAFG_01 V$TCF11MAFG_01 3.41E-03 1.00E+00 1.02E-02 7.13E-02 51 170 "SPTBN4,ATP6V0A1,BTK,JAZF1,P2RX6,NUMBL,KMT2C,NRXN2,RIMS2,SV2B,DMD,DRP2,EIF4G1,EIF5,RTN3,ZIC4,FGF12,FLNC,GAP43,PPARGC1A,KIRREL3,GRIK2,KCNA2,SFXN5,HECTD2,LRP1B,MEIS2,MITF,OMG,PCDH9,PPP2R2C,PSMA6,RASGRF1,NUDT11,RORB,SATB1,LRRTM4,SLC11A1,SHANK2,SNCB,SOX5,ST5,NUDT10,TAC1,POPDC3,TBL1X,PCDHA6,PCDHA1,TUBA3FP,UCHL1,CA10" Transcription Factor Binding Site V$RSRFC4_Q2 V$RSRFC4_Q2 3.42E-03 1.00E+00 1.02E-02 7.13E-02 54 182 "NME5,ASPH,ADGRB3,DIRAS1,CAPN3,USP2,DGKI,NRXN3,CNTN1,HS3ST5,HAPLN1,CTNND2,HDAC9,SV2A,DLG2,DMD,DTNB,EEF1A2,MBNL2,ELAVL4,EYA1,FGF12,GPR153,MYOZ2,HAS2,ZNF385B,ITGA7,KCNJ9,KCNN1,KTN1,TTYH2,ADAM11,MITF,MYL3,NDP,PCDH9,PDGFRA,RASGEF1B,PTPRO,RGS3,YJEFN3,SLC8A3,CPEB4,SOX5,ARHGAP26,FBXW11,ZFPM2,ITGB3BP,TPM2,TRPS1,CELF4,PMEPA1,JMJD1C,SSPN" Transcription Factor Binding Site V$OCT1_01 V$OCT1_01 3.71E-03 1.00E+00 1.10E-02 7.67E-02 63 219 "EMILIN3,CSMD3,ADORA2A,MTUS1,ALK,ANK3,BTK,SYNPR,NRXN3,NRXN1,RAB26,SNCAIP,PYGO1,HDAC9,DGKG,RHOBTB1,DLX1,DMD,RCAN1,PHC2,ETV1,HPCAL4,DLL3,TBR1,KLF12,KCNN3,MID1,MITF,SESN3,NDP,NFIA,NFIX,NKX2-2,PAX6,PBX1,PCDH8,PDE4D,GPR85,PDZRN4,NXPH1,POU3F4,CEP41,SLC6A15,ITSN1,SLC1A2,ATF7IP,CXXC4,KIF13A,SOX5,ZNF423,LMO3,NXT2,SYT1,TCF4,TCF12,SLC19A3,DNAH7,THRA,TRPS1,TSC1,PLPPR2,PCDH20,PRDM10" Transcription Factor Binding Site V$EVI1_05 V$EVI1_05 3.74E-03 1.00E+00 1.10E-02 7.67E-02 44 143 "ASIC2,CSMD3,SORCS1,JAZF1,CACNA1D,USP2,LGI1,HS3ST5,CREB5,IPCEF1,DMD,MBNL2,ELAVL4,SALL3,NEK6,PPARGC1A,GNAO1,GPR22,LPAR4,GRM3,PTGDR2,IGF1,LMO2,HECTD2,MBNL1,MEIS2,MID1,SESN3,CTNNA3,NCAM2,NF1,HCN1,CDK14,RFX4,RTN1,SOX5,SOX11,LMO3,SRPK2,NCDN,VAMP1,SATB2,ZFPM2,TSC1" Transcription Factor Binding Site CYTAGCAAY_UNKNOWN CYTAGCAAY_UNKNOWN 3.76E-03 1.00E+00 1.10E-02 7.67E-02 36 112 "DSCAML1,SLITRK1,NME5,AP1M1,CACNA1D,TBPL1,RGS6,DCTN1,EFNB3,MRPL10,GMPR2,TBC1D16,FGR,TPPP3,SDCBP2,GABRB3,GRIK2,GRIK5,GRM3,GABARAPL2,KCNMA1,PACRG,MARK3,NKX2-2,NRGN,PDE1A,SEC14L1,ZNF365,SLC6A8,TRERF1,SPATA7,DNAH7,CDK20,HSPBP1,TOM1L2,POLR3H" Transcription Factor Binding Site V$SMAD_Q6 V$SMAD_Q6 3.79E-03 1.00E+00 1.10E-02 7.67E-02 60 207 "NCKAP5,ARID1A,ADCY8,SPOP,PHF12,PRX,CADPS,CACNB2,CHRM1,CHRNB2,CREM,CSNK1E,ST18,FGFR1OP2,SNPH,NYAP1,RBM12,EIF4G2,ELAVL2,ELN,SRRM1,CACNG2,MEX3B,DACH2,GABRB1,GRIN2D,IL1RAPL1,SOX21,HPCA,LRRTM3,KCNA1,KCNC1,KCNH2,STMN1,MBNL1,MYH6,NEUROD1,CNOT4,NRGN,ZNF827,PIK3R1,POLG,SH3KBP1,PSD,ZNF532,FBXW7,SLC8A3,RIMS1,ZSWIM8,SPTAN1,NCDN,GSE1,SYT11,SEMA4A,NSD1,TNS2,CBX5,ZFP91,PMEPA1,JMJD1C" Transcription Factor Binding Site V$AP4_01 V$AP4_01 3.79E-03 1.00E+00 1.10E-02 7.67E-02 60 207 "DPF1,CSMD3,DOC2A,ANK2,SEMA7A,ADGRB2,MTMR3,CACNB2,USP2,CBFA2T2,DNAJB5,ZNF385A,DLX1,DMD,TLR7,EYA1,ATP8A1,SORBS1,CELF1,TPPP3,STARD10,STARD3,GRIN2D,GRM7,PTPRT,HAPLN2,IGF1,KCNH2,LMO1,NEUROD2,NRDC,OPCML,PCSK1,PDE3A,PLEC,NXPH1,PPP2R5E,MASP1,GDPD2,PTK2,RIT2,SALL1,HES6,TRIM46,EPN2,SNAP25,SNCA,SOX11,SOX15,LMO3,SEPT3,TCF7,CRB1,TP53BP1,RUSC1,SSBP2,CELF4,NAV3,PCBP4,JMJD1C" Transcription Factor Binding Site V$TAL1ALPHAE47_01 V$TAL1ALPHAE47_01 3.79E-03 1.00E+00 1.10E-02 7.67E-02 60 207 "ACLY,C1QTNF4,ABCD2,AMPH,OGT,B3GALT2,MAP7,FMNL3,ARHGEF2,REPS2,CDH2,NUMBL,SYNPR,ARHGAP22,HECTD1,PHACTR3,DAPK1,PABPC5,ELMO1,RHOBTB1,DMD,MBNL2,ELAVL4,RCAN2,CLVS1,NSG2,STAG2,GFRA1,GK,RAB30,GNAS,GPD1,GRM8,NXPH3,GABARAPL2,NKD1,MAP2,MARK1,MEF2C,MSI1,NDP,RCOR2,NEUROD2,NHLH1,NPR2,PDE1A,PDE4B,SH3KBP1,GTDC1,SEMA6D,HES6,ZNF821,RADIL,SLN,KDM4C,PLCB1,TAC1,FBXW11,TCF12,NAV3" Transcription Factor Binding Site V$AML1_01 V$AML1_01 3.83E-03 1.00E+00 1.10E-02 7.68E-02 58 199 "BCAR3,ANK3,MADD,ATP2A2,NGB,CLDN10,ARHGEF2,FOXN3,NRXN3,COL9A2,CREM,HINFP,SLITRK5,ARHGAP32,SLC12A6,PLXNC1,AKAP3,TACC2,CELF1,HHIPL1,RAB30,GPD1,ADAMTS8,LMO2,ARHGAP12,MEIS2,MRPL42,BLOC1S2,RCOR2,NUCB2,PAX6,PDE3B,PDZRN4,RAB39A,MDGA2,STRC,RAB5B,CRTAC1,PRR5L,SCN2B,SCN8A,SLC6A9,ATF7IP,SCN3B,SOX5,KIF1B,LMO3,FGD4,SLC37A2,SEMA4A,TCF12,SIRT1,TLL2,TPM1,MKRN3,NAV3,FAM13C,JMJD1C" Transcription Factor Binding Site V$AML1_Q6 V$AML1_Q6 3.83E-03 1.00E+00 1.10E-02 7.68E-02 58 199 "BCAR3,ANK3,MADD,ATP2A2,NGB,CLDN10,ARHGEF2,FOXN3,NRXN3,COL9A2,CREM,HINFP,SLITRK5,ARHGAP32,SLC12A6,PLXNC1,AKAP3,TACC2,CELF1,HHIPL1,RAB30,GPD1,ADAMTS8,LMO2,ARHGAP12,MEIS2,MRPL42,BLOC1S2,RCOR2,NUCB2,PAX6,PDE3B,PDZRN4,RAB39A,MDGA2,STRC,RAB5B,CRTAC1,PRR5L,SCN2B,SCN8A,SLC6A9,ATF7IP,SCN3B,SOX5,KIF1B,LMO3,FGD4,SLC37A2,SEMA4A,TCF12,SIRT1,TLL2,TPM1,MKRN3,NAV3,FAM13C,JMJD1C" Transcription Factor Binding Site CTAWWWATA_V$RSRFC4_Q2 CTAWWWATA_V$RSRFC4_Q2 3.98E-03 1.00E+00 1.14E-02 7.96E-02 82 298 "NDRG2,SLC12A5,NME5,PRX,ASPH,DIRAS1,CAPN3,USP2,DGKI,MYOM2,NOG,CFL2,CHN2,CNTN1,HAPLN1,NCOR1,SNCAIP,SIPA1L1,CTNND2,RIMS2,HDAC9,RHOBTB1,SV2A,DLG2,DMD,EEF1A2,ELAVL4,RASGRP2,EYA1,ZIC4,FGF12,GPR153,STAG2,MYOZ2,PPARGC1A,PCDH11X,GPM6B,LPAR4,GRIN2D,IGF1,LRRTM1,ITGA7,KCNN1,KTN1,TTYH2,MAT2A,ADAM11,MGAT3,GIT1,MYH3,NDP,RETREG1,PDZRN4,PRRX1,POU3F4,RASGEF1B,SYTL2,PTPRO,USP47,RASGRF1,YJEFN3,SCN4B,LRRTM4,ITSN1,SLC8A3,SLC9A5,ELMO2,EFHD1,CPEB4,TTC17,SOX5,SPTB,FBXW11,SIK3,ITGB3BP,TPM2,TPM3,TSC1,CELF4,SH3GLB2,PMEPA1,PLSCR4" Transcription Factor Binding Site TGGNNNNNNKCCAR_UNKNOWN TGGNNNNNNKCCAR_UNKNOWN 4.11E-03 1.00E+00 1.17E-02 8.17E-02 91 336 "NCKAP5,ADD3,C1QTNF1,PHF12,DGKD,RASL11B,ATP2A2,B3GALT2,ADAM23,RGN,CBFA2T2,ARHGEF2,ASIC3,CHRM1,NRXN3,CLCN3,GAL3ST1,CREB5,CS,SNCAIP,KIAA0040,ELMO1,WDPCP,EIF4G2,LRRC17,MRVI1,FGF11,FHL1,TPPP3,JPH4,PPARGC1A,NTNG2,GLS,STARD3,PLCD4,SHISA6,RBPJ,USP54,IGSF1,SCRT2,LRRTM1,KCNH2,KCNN3,MEF2C,MID1,MOV10,MPP2,CTNNA3,MYCN,NEK1,NEUROD2,NFIA,NFYA,NNAT,NPPA,DDR2,PCDHGC3,NLGN3,FXYD1,PLXNB1,PDZRN4,MAGEL2,NXPH1,PPARA,MAPK3,GDPD2,PTHLH,RPE65,EMID1,RTN1,SALL1,SCN4B,TRIM46,CPEB3,SOX15,SPTB,KIF1B,KANK1,VAMP1,RALYL,HIF3A,ZFPM2,HEY1,TIMP4,DDHD1,CHST5,NR2C2,UBE2H,ZNF189,PCBP4,JPH3" Transcription Factor Binding Site V$AREB6_04 V$AREB6_04 4.25E-03 1.00E+00 1.20E-02 8.42E-02 60 208 "PKP4,HIP1R,FOXN3,ZNF521,PABPC5,DLG2,DMD,WDPCP,EDN1,EIF4G1,ELAVL4,PAN3,RACK1,PPP1R1B,FGF13,STAG2,GART,ATOH8,KLF12,HMGB1,AGBL5,ITIH2,SHC3,MEIS2,MXI1,NF1,NFIX,OMG,PDE3B,PLEC,SLC25A23,PURG,PDZRN4,SDK2,LRRN3,PPP3CB,MAPK3,RASGRF1,RFX5,LGI2,ROM1,SLN,SNAP25,SON,TRERF1,SOX10,SOX11,KDM3A,NMNAT2,SPART,ST5,TCF4,TJP1,TRPS1,FLRT1,WRN,XPO1,SLC30A3,NAV3,PCBP4" Transcription Factor Binding Site V$TCF4_Q5 V$TCF4_Q5 4.31E-03 1.00E+00 1.22E-02 8.50E-02 58 200 "ARID1A,ABCD2,ARHGAP20,FGF17,NRP2,BMP7,CBFA2T2,CHN2,SYNPR,IGDCC3,CDC42BPB,HAPLN1,SPOCK2,DCT,ELMO1,DLX1,EDN3,EYA1,ZIC4,SORBS1,PPARGC1A,EML4,MAP4K5,HAS2,NKD1,LRRTM3,LIFR,SMAD1,MITF,SCG3,MYL3,RCOR2,NFIX,NPPA,OGG1,PCDH8,PRRX1,PPP2R5C,PRKCB,PROX1,SYTL2,TNFRSF19,SOX6,SOX5,MESP1,NCDN,STX1A,ANKRD28,TCF7,TCF7L2,RALYL,TLL2,UBE3A,ZIC1,PRDM2,NAV2,PCBP4,SLC17A6" Transcription Factor Binding Site V$HSF_Q6 V$HSF_Q6 4.37E-03 1.00E+00 1.23E-02 8.57E-02 46 152 "NCKAP5,AMPD2,ANK3,GAS7,CACNA1G,LGI1,CHRM1,DNAJB5,MAP4K4,CALY,EDN1,CNNM1,ELAVL2,GPHN,SEMA6C,ATP2C1,STAG2,GAD2,CPLX2,CYP46A1,LYVE1,GRIA4,GRM8,GSN,HSPA1L,MAP6,MID1,PTOV1,HS6ST3,RCOR2,NFIA,NKX2-2,NNAT,PCSK1,DPF2,RFX4,MYH14,ROBO1,ATP8B4,KCNIP1,RTN1,SNAP25,HSPBP1,UBE2H,UCHL1,SLC4A10" Transcription Factor Binding Site V$PR_01 V$PR_01 4.53E-03 1.00E+00 1.26E-02 8.85E-02 37 117 "ADCY6,ADGRB3,FGF17,GREB1,ARHGAP32,PABPC5,ELMO1,C2CD2L,DLG3,KLHL5,ELAVL4,TUBB4A,IP6K2,AGAP2,SYNCRIP,MSTN,RAB30,USP54,LRRTM3,MBP,KCTD6,NHLH1,PCDH8,PCDH9,PROX1,PYGM,FIGN,RGS3,RTKN,ATF7IP,NCDN,MPRIP,NSD1,TNS2,AMOT,FSTL5,JMJD1C" Transcription Factor Binding Site V$EGR1_01 V$EGR1_01 4.85E-03 1.00E+00 1.35E-02 9.43E-02 58 201 "CSMD3,APP,CACNA1A,CACNA1E,CAMK2A,CBLN1,CDH2,KCNAB3,NUMBL,CLTC,DNAJB5,RAB26,AKAP12,SOCS5,MATR3,EGR3,EPHB1,GPHN,PCDH17,GRIN1,ATE1,KAT7,PACSIN2,KCNB1,KCNC1,KCND2,KCNN2,MAN2A2,MEF2C,GIT1,MSI1,NEUROD2,NRGN,ZNF827,PBX1,PCSK2,SLC25A23,SH3KBP1,RAB39A,RBBP6,RFX4,FAM192A,LRFN5,SCN8A,SEC14L1,TRA2B,SH3GL3,CLSTN1,FAM214B,SPTB,PJA1,ICAM5,TPM4,UBTF,USP1,VGF,PORCN,SF1" Transcription Factor Binding Site V$HSF2_01 V$HSF2_01 4.88E-03 1.00E+00 1.35E-02 9.45E-02 57 197 "ACTN2,PCDH10,NOL4,CDK5R1,CACNA1D,CACNA2D2,PPT2,DNAJB5,CREM,GREB1,RIMS2,DMD,HS3ST4,SHANK1,ABCC5,EFNB3,MBNL2,EGR3,EIF4G2,EIF5,ELAVL4,RASGRP2,FHL1,FLNC,STAG2,GABRB1,GAD1,NEK6,RAB30,GRIK1,GRM1,CLASRP,IL1RAPL1,ELOVL5,HSPA1L,SMAD1,MAP2,MAT2A,SHC3,MEF2C,MID1,MOBP,HS6ST3,NNAT,ENPP2,PLEC,RALGDS,RFX4,TRERF1,KDM3A,SPTB,TAB2,FNDC9,RALYL,TPM2,NR2C2,WRN" Transcription Factor Binding Site V$MAZ_Q6 V$MAZ_Q6 4.96E-03 1.00E+00 1.36E-02 9.55E-02 44 145 "ARID1A,APBB1,ATP1A1,ADGRB2,CAMK2G,NEURL1,ARHGEF2,CNN3,CREM,CTNND1,PHC2,EIF4G2,EMX2,WAC,CELF1,OGA,GFRA1,GRIK3,ZNF496,PTPN5,HPS5,TLX1,HPCA,KCNC1,PIK3AP1,MDM4,MOV10,RCOR2,NPPA,PAX6,PBX1,PROX1,RFX5,KCNIP2,TRIM46,CLSTN1,POGZ,ST5,NCDN,SYT11,TCF7L2,ZFP91,TPM3,CA14" Transcription Factor Binding Site V$MSX1_01 V$MSX1_01 4.98E-03 1.00E+00 1.37E-02 9.56E-02 45 149 "BCAR3,ARNTL,NOL4,CALM1,CBFA2T2,NOG,SPOCK2,ELMO1,CCDC3,DLX1,ELAVL2,PIPOX,EYA1,ZIC4,FOXG1,GAD1,GPR12,IL1RAPL1,LIMS1,SMAD1,ADAM11,MITF,MDGA1,NDP,NKX2-2,PCDHGC3,PMP22,ING3,CEP41,SYTL2,ZNF532,SALL1,ARX,TRERF1,SPTB,KIF1B,NCDN,SIK3,CBX5,VAV1,ZIC1,STMN4,KCNAB1,MPPE1,CBLN2" Transcription Factor Binding Site V$FOXJ2_01 V$FOXJ2_01 5.00E-03 1.00E+00 1.37E-02 9.56E-02 46 153 "ATP2A2,ADGRB3,CH25H,CDH10,LGI1,CHN2,CREB5,RGS6,DMD,E2F5,NSG2,GAP43,MSTN,GFRA1,PCDH17,MSL3,GNAO1,GRM3,KLF12,HSF2,MEF2C,MITF,SCG3,NCAM1,NEUROD2,NOVA1,KCNK10,PIK3C2A,KCTD15,PLEC,PKIA,SOX6,FBXO11,PREX2,CPEB4,SLN,TRERF1,POGZ,NCDN,HEY2,C5orf64,TNR,TRPS1,CELF4,RGMA,PHTF2" Transcription Factor Binding Site V$CRX_Q4 V$CRX_Q4 5.19E-03 1.00E+00 1.41E-02 9.86E-02 63 222 "SLITRK1,SLC12A5,CASK,ATP1B3,C5,BTRC,CAMK2A,LDB2,RAB33A,NRXN3,ZNF385A,CREB5,ATRNL1,DCTN1,DLG4,DMD,DMPK,ERBB4,EFS,DLC1,SLC9B2,FGF14,FOXG1,FLNC,GAP43,KCNA1,KCNH2,LIFR,MEIS1,MN1,MDGA1,NFIX,NOS1,CNOT4,PAX6,PCDHGC3,PCSK1,PDE4D,PRRX1,KCNIP2,SATB1,LRRTM4,NLGN1,SLC1A7,CPEB4,RIMS1,SOX15,LMO3,SRPK2,SST,FNDC9,ROBO3,SATB2,TCF7,TCF7L2,CLASP1,SYNE1,NR2E1,TNNT1,ZNF384,SSBP2,FLRT1,JMJD1C" Transcription Factor Binding Site V$OCT_C V$OCT_C 5.24E-03 1.00E+00 1.42E-02 9.92E-02 62 218 "EMILIN3,ADORA1,ADORA2A,MTUS1,ALK,SEMA7A,LDB2,CBFA2T2,CDH10,SYNPR,NRXN1,RAB26,PCYT1B,SNCAIP,HDAC9,DGKG,DLX1,DMD,DPYSL2,RCAN1,SUGP2,EML1,ETV1,FGF12,FGF14,FOXG1,SEMA6C,GAP43,GCNT2,RAB30,GPM6A,KCNN3,KCTD6,MMP17,SESN3,MYBPC1,NFIA,PAX6,PCDH8,PDE4D,TMOD2,CDK14,PRRX1,POU3F4,SLC6A15,SALL1,MRAS,ITSN1,SH3GL3,SLC1A2,KIF13A,LMO3,NXT2,THRA,TLL2,NR2E1,TSC1,PLPPR2,VSNL1,ZIC3,FSTL5,PRDM10" Transcription Factor Binding Site V$STAT4_01 V$STAT4_01 5.35E-03 1.00E+00 1.44E-02 1.01E-01 60 210 "ACTN1,MTUS1,PKP4,CACNA1E,USP2,LGI1,CLOCK,CSF3R,FEZ2,CALY,DOCK4,PITPNC1,EDN1,HIPK3,GPHN,EXTL2,CACNG3,FGF12,FOXG1,FLT1,NSG2,PPARGC1A,ADAP1,EML4,STMN2,GRIA1,HNF4G,IGF1,ZNF385B,TTYH2,MBNL1,MEF2C,MITF,MYL3,NCAM1,KCNK10,PBX1,PDE4D,ZDHHC8,ABCB1,SMOX,PRKCB,MAPK10,PRR5L,FAM192A,SATB1,TNFRSF19,SGK1,CPEB4,CXXC4,TRERF1,ANKRD28,PDLIM2,AP4E1,C5orf64,CA14,VSNL1,PRDM10,EPM2A,JMJD1C" Transcription Factor Binding Site V$TEF_Q6 V$TEF_Q6 5.40E-03 1.00E+00 1.45E-02 1.01E-01 59 206 "ASIC2,DSCAML1,DPP10,PPFIA3,CACNA1D,SYT6,CAST,SPAG9,DGKI,LGI1,CREB5,CSNK1E,BOC,DOCK4,DPYSL2,WDPCP,EMX2,EN2,EYA1,FGF12,HPCAL4,IP6K2,ARPP21,SALL3,GBX2,MSL3,PCDH11X,GRM5,KLF12,IGF1,CDH20,KCNJ16,ZFYVE27,MAP2,NDP,NFIX,NPTX2,PAX6,PBX1,PDE4B,PPP2R2B,PRKACB,RAB5B,RGS3,ROBO1,RIMS1,TRERF1,FNBP1,ZNF423,NCDN,PUM2,CRB1,HEY1,KAT6B,TNR,UBE2H,ZIC2,USP32P2,SLC39A12" Transcription Factor Binding Site YGTCCTTGR_UNKNOWN YGTCCTTGR_UNKNOWN 5.44E-03 1.00E+00 1.45E-02 1.02E-01 27 80 "SYT13,ATP2A2,KCNAB3,CS,SOCS5,ELAVL2,EMX2,PHYHIPL,GABRA3,GK,HRH3,KCNJ16,ADAM11,MT3,NPTX2,PTPA,SEMA6D,SCN2B,CXXC4,SNCB,RGL1,ANO4,TRIM2,CHST8,THRA,VGF,ZIC3" Transcription Factor Binding Site V$AP1_Q4_01 V$AP1_Q4_01 5.85E-03 1.00E+00 1.55E-02 1.09E-01 62 219 "CSMD3,NDRG2,ADCY8,SLC24A4,ANXA7,PRX,MARK4,ADAM15,BACH1,BTK,CALB2,DIRAS1,USP2,P2RX6,CSF1R,C2CD2L,SV2B,AK5,HS3ST2,USP3,DYRK1A,ELAVL2,EPB41L1,RTN3,TUBB4A,FGF11,FGF12,UBE2E3,MYOZ2,PCDH17,LYVE1,GRIA1,MAP4K5,SYNPO,RBPJ,ZNF385B,LRRTM3,KCNA2,MAP2,MAP4,MARK1,SHC3,MSI1,NDP,NEFH,OLR1,OMG,ZNF827,SNX10,PLCD1,PTPRN,MYH14,ROM1,RIMS1,SNCB,SRPK2,NCDN,GSE1,COBL,ANKRD28,FBXW11,TUBA3FP" Transcription Factor Binding Site V$MAF_Q6 V$MAF_Q6 5.91E-03 1.00E+00 1.57E-02 1.10E-01 61 215 "ACTN1,ADORA3,ALCAM,PCDH10,FGD2,PHF12,CNTNAP1,GAS7,NUMB,SPAG9,CHM,SYNPR,RAB33A,NRG2,CALN1,DYRK1A,EFNB3,ELAVL4,FGF13,SYNCRIP,FLT1,ZNF512,GABRA3,MSL3,GRM3,MAP4K5,HAS2,TLX1,NEGR1,ITPKB,KCNJ16,LAMP2,MEIS2,MITF,NKX2-2,NOVA2,OGG1,PAX6,PDGFRA,PIK3CD,KCTD15,POLG,PPP2R5C,SATB1,PPM1E,SLA,FAM214B,SNAP25,TRERF1,SOX2,NPAS3,STAC2,SEMA4A,PCDHAC2,TIAM1,TTC3,AMOT,VAV2,NUP214,JMJD1C,CBLN2" Transcription Factor Binding Site V$MYB_Q6 V$MYB_Q6 6.10E-03 1.00E+00 1.61E-02 1.12E-01 58 203 "AK2,ANK2,SEMA7A,PPP4R4,ASPA,B3GALT2,CACNA1G,CACNB2,CAMK2A,SPAG9,RGN,DLGAP1,CHN1,RAB3C,MAP4K4,ARHGEF6,MICAL2,SPOCK2,CHRDL1,DLG3,DLX1,EIF4G2,BSCL2,EPB41,RCAN2,GMPR2,FGF12,FYN,GCNT2,PCSK1N,GNAS,GNG3,SYNPO,AGBL5,IGSF1,IL11RA,ARHGAP12,MAP4,SESN3,NOVA2,DDR2,ODF2,PCDH9,CDK14,ING3,NXPH1,MDGA2,RFX4,LRFN5,HES6,MYO18A,ANKRD28,TNS2,TRPC1,SSBP2,UBE2H,FSTL5,JPH3" Transcription Factor Binding Site AGCYRWTTC_UNKNOWN AGCYRWTTC_UNKNOWN 6.17E-03 1.00E+00 1.62E-02 1.13E-01 30 92 "CASKIN1,C1QTNF4,ALS2,HIP1R,LGI1,CLTC,HAPLN1,DMD,FGF12,TBR1,MPP6,MSTN,KIRREL3,GRM3,SOX21,PTGDR2,IGF1,LMO1,DDX25,SLCO1C1,PDE3B,MASP1,PTH1R,GSE1,RALYL,SIRT1,ZFP91,NR2E1,TNR,NAV2" Transcription Factor Binding Site V$LHX3_01 V$LHX3_01 6.26E-03 1.00E+00 1.63E-02 1.14E-01 55 191 "ADRB2,SLC24A4,SEMA6A,PCDH10,EPB41L5,ARNTL,LDB2,CHN2,DCT,ELMO1,DMD,CALN1,KLHL5,PPP1R1B,TBR1,GABRG1,SALL3,GNAO1,GPR22,GRM5,HAS2,SCRT2,LRRTM1,KCNMA1,KCNN3,MBNL1,ADAM11,MID1,NFYA,NOVA1,SNTG1,PCSK2,KCTD15,PDZRN4,PRRX1,PPP2R2B,PTH1R,PTPRO,FIGN,RGS12,ROBO1,RORB,UNC5B,LMO3,SRPK2,STAC2,SULF2,GSE1,ADAMTS17,TAC1,HHIP,KAT6B,FIP1L1,SSPN,JPH3" Transcription Factor Binding Site V$ATF1_Q6 V$ATF1_Q6 6.26E-03 1.00E+00 1.63E-02 1.14E-01 55 191 "ADARB2,SYT13,NOL4,CACNA1G,CDC42,CFL2,CHGB,NRXN1,SULT4A1,CNN3,CREM,KCTD8,PARD6A,DLG2,HS3ST2,MBNL2,PLEKHA1,NCALD,FLT1,GABRG2,RUNDC3A,GK,RNPS1,LOXL3,GPM6B,ELOVL5,KCNA6,SCAMP5,NDP,NOVA1,NOVA2,NTRK2,OGDH,PCSK1,PDE1A,PDE4D,PPP2R5C,MAPK10,RET,KCNIP2,SNAP25,SOX11,C11orf87,SST,GSE1,FBXW11,HHIP,THRA,NR2E1,DAAM2,TPM4,UBE2H,VGF,SLC38A1,SCG2" Transcription Factor Binding Site V$VDR_Q3 V$VDR_Q3 6.30E-03 1.00E+00 1.63E-02 1.14E-01 54 187 "ARID1A,SLC12A5,AP1B1,PHF12,PRX,ATP1A2,CALM1,ARHGEF2,NUMBL,CHRM1,ZNF385A,SLITRK5,EFNB3,EIF4G2,AGAP2,TBR1,STAG2,GDF1,ATF7,GRM3,KCNB1,KCND1,LMO1,MEIS2,MSI1,NCAM1,NEUROD2,NHLH1,NRGN,NTRK3,PBX1,NLGN3,PLXNB3,POLG,SH3KBP1,PROX1,RBBP6,RFX5,PRIMA1,KCNIP2,SATB1,DHX30,FAM214B,CXXC4,TRERF1,SOX10,SOX15,POGZ,HIF3A,THRA,TRPS1,XPO1,SLC26A10,FBXO36" Transcription Factor Binding Site V$GRE_C V$GRE_C 6.70E-03 1.00E+00 1.73E-02 1.21E-01 33 104 "NCKAP5,TRMT9B,ATP1A3,FGF17,BTK,AP4M1,RIMS2,WDPCP,MBNL2,ELAVL4,ARPP21,GLYR1,GPD1,ATF7,WIF1,LSAMP,MEF2C,MYL3,NNAT,NPR2,PIK3R1,KCTD15,PRRX1,LRRN3,ZNF532,RTKN,ARX,SLC6A11,KIF13A,LMO3,TCF12,NSD1,UBE3A" Transcription Factor Binding Site YGCGYRCGC_UNKNOWN YGCGYRCGC_UNKNOWN 6.76E-03 1.00E+00 1.73E-02 1.21E-01 67 241 "ASIC1,METAP1D,SLC12A5,SEMA6A,USP37,PPP4R4,ARRB2,ASCL1,ATP2A2,CDK5R1,MTMR3,NEURL1,MAGI1,RAB33A,ZNF521,C2CD2L,EXOG,CDON,PLEKHA1,DCTN4,WAC,ACSL4,PRKAG2,SYNCRIP,PHYHIPL,GABRA4,JPH4,MTHFD2,STARD10,GBX2,GNAS,NXPH3,KCNC1,KCNN1,PACRG,MAPT,MEIS2,MMP16,NEUROD1,PENK,PMP22,PPP3CC,PSD,ZCWPW1,ZDHHC14,RGS7,PBRM1,ROM1,LRFN5,PUF60,PPM1E,KANSL3,SLC9A5,SORCS3,KDM4C,SPTAN1,GSE1,GALNT17,TIAM1,ZFP91,NR2C2,UBTF,SF1,ZIC2,CA10,GOPC,TIGD6" Transcription Factor Binding Site TTCYRGAA_UNKNOWN TTCYRGAA_UNKNOWN 6.76E-03 1.00E+00 1.73E-02 1.21E-01 67 241 "NCKAP5,SEMA6A,GAS7,PROM1,CACNA1I,CDK5R2,CAMK2B,LGI1,CDR1,CLU,DNAJB5,SLC25A27,IPCEF1,CNTNAP2,RIMS2,EMX2,EPB41L1,LRRC17,ETV1,SYNCRIP,FLNC,STAMBP,ATP2C1,STAG2,MEGF10,GABRA1,GABRB1,GABRB3,GCNT2,CYP46A1,HPGDS,GPR22,GRB10,GRIN2D,CELF3,KCNH2,MAPT,MAT2A,MGAT3,MYT1,NNAT,NODAL,PCDH8,PIK3R1,PRPH,PTHLH,ZDHHC14,LGI2,RTN1,SCN3A,TRA2B,EFHD1,CXXC4,SRPK2,SATB2,RALYL,ARHGEF12,CDH22,WBP2,ZNF384,UCHL1,FLRT1,XPO1,PRDM2,KCNAB1,PLSCR4,NETO1" Transcription Factor Binding Site V$AR_01 V$AR_01 6.96E-03 1.00E+00 1.77E-02 1.24E-01 35 112 "SLITRK1,AMPH,CLDN10,USP2,BRINP1,DTNB,CALCRL,OLFM1,IP6K2,SDCBP2,IP6K3,USP54,ITGA7,ITPKB,JAK2,KCNH2,LIFR,SMOX,FXYD1,PMP22,PPP3CB,PSMA6,ZNF532,RTKN,SGK1,SLC9A5,LGI3,SNAP25,KIF13A,TRERF1,SOX10,NCDN,TP53BP1,VGF,WNT7A" Transcription Factor Binding Site V$FOXO1_02 V$FOXO1_02 7.02E-03 1.00E+00 1.77E-02 1.24E-01 55 192 "C1QTNF3,STX16,CACNA2D1,CAMK2G,CFL2,FOXN3,SNCAIP,CSNK1G3,PITPNC1,DDX46,EIF4G1,TENM1,EML1,EN2,ETV1,EZH1,FOXG1,SALL3,GCNT2,BRD8,GNAO1,GNAS,IL1RAPL1,MAP4K5,KLF12,IL6ST,KCNA1,KCNJ16,LIFR,MEIS2,MITF,MOBP,MDGA1,NDUFA5,NFIX,NKX2-2,PIK3C2A,PCDH18,PPM1B,MAPK10,PROX1,ARID4A,SEMA6D,SH3GL3,CLSTN1,TRERF1,ST5,ANKRD28,TBL1X,SATB2,TCF7,TEK,THRA,RASD2,JPH3" Transcription Factor Binding Site V$CMYB_01 V$CMYB_01 7.02E-03 1.00E+00 1.77E-02 1.24E-01 55 192 "ASIC1,ADD3,CDC14B,ARNTL,ATP2B2,CANX,SPAG9,USP2,CDC27,DLX1,TOM1,EGR3,ERBB4,EYA1,GMPR2,WAC,CACNG2,ZIC4,SCML2,FGF12,POMT1,STAG2,IL1RAPL1,ZBTB49,AGBL5,ITPKB,STMN1,ARHGAP12,PIK3AP1,MXI1,NFYA,NOVA2,NRGN,ODF2,PBX1,PDZRN4,SH3KBP1,PTPA,RBBP6,HES6,ZNF821,PPM1E,DHX30,CPEB4,EPC1,LMO3,POGZ,VPS13A,TIMP4,NR2E1,C5orf64,TPM3,UBE2H,PRDM10,RTN4" Transcription Factor Binding Site WCAANNNYCAG_UNKNOWN WCAANNNYCAG_UNKNOWN 7.02E-03 1.00E+00 1.77E-02 1.24E-01 55 192 "PCDH10,PHF12,DOCK11,BTRC,ARHGEF2,CHM,PLEKHB1,CNGA3,CNTFR,SMARCAL1,HS3ST5,C2CD2L,SV2A,DMD,USH1C,EGR3,EPB41L2,ENPP6,FGFR1,FGFR3,POLK,SYNCRIP,FOXM1,SYT3,NSG2,STAG2,ZNF274,GBX2,RAB30,MSL3,KCNJ5,HECTD2,MYH6,HNRNPM,NCAM1,NFIX,CNOT4,NUMA1,PCDH8,PPP2R2B,MAPK10,TRAPPC13,SALL1,SCN2B,SCN8A,SLC6A9,SOX1,SOX2,TAB2,WBP2,SMUG1,ZNF32,PHTF2,FBXO36,DPF3" Transcription Factor Binding Site TGACGTCA_V$ATF3_Q6 TGACGTCA_V$ATF3_Q6 7.08E-03 1.00E+00 1.77E-02 1.24E-01 54 188 "SLC25A25,ADCY8,PKP4,ALS2,NOL4,CAMK2D,SPAG9,KYAT1,SYNGR3,CHGB,SULT4A1,CREM,PHACTR3,KCTD8,DCTN1,PARD6A,G3BP2,HS3ST2,RCAN1,MBNL2,ING4,EPB41,NCALD,DNAJC27,ZMYND15,FLT1,PPARGC1A,RUNDC3A,GPM6B,ADAP1,ELOVL5,KCNF1,ZFYVE27,SCAMP5,MITF,NF1,OGDH,PCSK1,PNMA3,MAPK10,RPRD1A,SNAP25,SPATA7,C11orf87,SST,NR2E1,DAAM2,RUSC1,UBE2H,VGF,ZNF184,SLC38A1,SCG2,NUP214" Transcription Factor Binding Site KCCGNSWTTT_UNKNOWN KCCGNSWTTT_UNKNOWN 7.09E-03 1.00E+00 1.77E-02 1.24E-01 29 89 "ACLY,OGT,ASCL1,PTBP2,ARMCX2,USP3,DMTF1,EIF4G2,RGS17,SRRM1,SYNCRIP,FOXO3,CELF1,STAG2,HNRNPK,RBPJ,MEIS2,NCAM1,PPP2R2B,TRA2B,KANSL3,KDM3A,SYT11,ADGRL3,ZFP91,UBC,XPO1,SF1,PAK5" Transcription Factor Binding Site V$MAZR_01 V$MAZR_01 7.14E-03 1.00E+00 1.77E-02 1.24E-01 53 184 "ABR,PHF12,ADGRB2,FGF17,CAMK2G,TRIM41,CDC27,CLOCK,SLITRK5,DMPK,EIF4G1,RTN3,EYA1,ZIC4,FGF14,MEX3B,SYT3,DLL3,JPH4,GART,GRIK1,GRIN2D,IL1RAPL1,GABARAPL2,HMX1,HPCA,KCND3,KCNH2,MAPT,MEIS2,MOV10,NEUROD2,NPTX1,PAX6,FXYD1,TNPO2,POU3F2,PRKCG,SALL1,LRFN5,LRRTM4,URGCP,SON,TRERF1,POGZ,EPB41L3,SEPT3,TCF7L2,TRPS1,SSBP2,SF1,PCBP4,NETO1" Transcription Factor Binding Site V$OCT1_05 V$OCT1_05 7.43E-03 1.00E+00 1.84E-02 1.29E-01 60 213 "EMILIN3,ADORA1,MTUS1,SEMA7A,ATP2A2,NRP2,PROM1,BTK,LDB2,LGI1,CTNND1,DGKG,RHOBTB1,DLX1,DMD,EDN1,SUGP2,FGF14,SEMA6C,TBR1,GABRB1,GPM6A,STMN2,IL1RAPL1,HMGB1,KCNN3,LIG4,MID1,MYBPC1,NOS1,PAX6,PCDH8,PDE4D,TMOD2,PRRX1,LRRN3,CEP41,PRKCB,SLC6A15,RGS3,LRFN5,MRAS,SH3GL3,PPM1E,PKNOX2,TRERF1,SOX5,ZNF423,LMO3,SYT1,SATB2,TCF12,SLC19A3,THRA,TLL2,NR2E1,UBE3A,PLPPR2,FSTL5,PRDM10" Transcription Factor Binding Site V$GR_Q6_01 V$GR_Q6_01 7.52E-03 1.00E+00 1.85E-02 1.30E-01 59 209 "ANK3,AQP4,BACH1,BCL7A,NRP2,SYT6,CDH2,LGI1,NOG,QKI,AKAP7,AKAP5,MAGED1,ATRNL1,GREB1,CTNND2,C2CD2L,SV2B,KLHL5,MBNL2,EIF4G2,ELAVL2,ELAVL4,GMPR2,ZIC4,TUBB4A,ATP8A1,SYNCRIP,ARPP21,RND1,LOXL3,GPM6A,IL1RAPL1,LRRTM3,STMN1,SESN3,NHLH1,KCNK10,PCDH8,PCDH9,PDYN,KCTD15,SCHIP1,PPM1B,PRKCG,MASP1,ZNF532,RTKN,ZNF423,EPB41L3,NCDN,ELOVL4,FGD4,TPM1,NSD2,ZNF24,PCBP4,JMJD1C,DPF3" Transcription Factor Binding Site V$AP2GAMMA_01 V$AP2GAMMA_01 7.69E-03 1.00E+00 1.89E-02 1.32E-01 57 201 "KCNH8,ARID1A,DSCAML1,GAS7,APLP1,CABP7,CALM1,SPAG9,LHX2,ZNF385A,SLITRK5,DGKG,C2CD2L,CHRDL1,NYAP1,CDON,DSCAM,PHC2,EFNB3,PLXNC1,CERCAM,MRVI1,SCML2,FGF11,ATP5PD,SEMA6C,MSTN,GRIK3,NR3C1,KLF12,KITLG,MYH7,RCOR2,PAK3,SPATA6,POU3F2,PTPRG,PPM1E,FRMPD1,SLC6A11,SLC12A4,CPEB4,TRERF1,SOX5,SOX10,SP4,PDLIM2,ADGRL3,NR2C2,TRPC1,UBE2H,UBTF,KCNK12,SLC30A3,LRP8,TIGD6,DPF3" Transcription Factor Binding Site V$GATA4_Q3 V$GATA4_Q3 7.78E-03 1.00E+00 1.90E-02 1.33E-01 56 197 "ACTN1,ALK,ALDH4A1,ATP2B3,ADGRB2,ARHGEF2,CHN2,CHRM1,CNR1,PCYT1B,AKAP6,ZNF521,CTNND1,TOMM20,DMD,EGR3,ASB3,ELAVL2,ZIC4,FCGR1A,STAG2,ARPP21,PPARGC1A,LYVE1,GRM1,LRRTM3,LIFR,LMO2,MBNL1,MEIS1,MEIS2,NDP,NNAT,NOS1,PDE4D,PPP2R5C,RFX5,SCN3A,LRRTM4,TNFRSF19,SLC8A3,CPEB4,SMARCE1,TRERF1,SOX2,SOX5,LMO3,ANKRD28,TCF7L2,HHIP,HIRA,AMOT,VGF,SF1,ZIC1,CELF4" Transcription Factor Binding Site V$STAT3_02 V$STAT3_02 8.26E-03 1.00E+00 2.01E-02 1.41E-01 37 121 "ASIC2,BCL7A,CHRM1,ZFYVE9,MAML1,SV2B,HEYL,EGR3,EIF4G1,GPHN,GABRB1,CPLX2,KIRREL3,RND1,GRIN2D,RBPJ,KCNN2,KCNN3,MEIS2,HS6ST3,MYT1,NCAM1,NELL2,CRTAC1,RGS3,ASIC4,ARX,NAPB,RIMS1,ZSWIM8,TCF7L2,UBTF,FLRT1,VSNL1,CA10,NAV2,PCBP4" Transcription Factor Binding Site V$ATF_B V$ATF_B 8.38E-03 1.00E+00 2.03E-02 1.42E-01 46 157 "SLC25A25,ADCY8,PKP4,NOL4,CAMK2D,SPAG9,CHGB,SULT4A1,CREM,PHACTR3,KCTD8,DCTN1,PARD6A,HS3ST2,RCAN1,MBNL2,ING4,EPB41,NCALD,FLT1,PPARGC1A,RUNDC3A,GPM6B,ADAP1,ELOVL5,KCNF1,MBNL1,SCAMP5,MITF,NEK1,OGDH,PAK3,PNMA3,MAPK10,RPRD1A,SNAP25,C11orf87,SST,TACR1,HHIP,NR2E1,DAAM2,RUSC1,UBE2H,VGF,SCG2" Transcription Factor Binding Site TAAWWATAG_V$RSRFC4_Q2 TAAWWATAG_V$RSRFC4_Q2 8.41E-03 1.00E+00 2.03E-02 1.42E-01 40 133 "SEMA6A,ADAM23,NRP2,CAPN3,USP2,DGKI,NOG,NRXN3,CTNND2,HDAC4,SV2A,ELAVL4,DLC1,FGF13,IP6K2,STAG2,PPARGC1A,LPAR4,GPER1,ZNF385B,KCNJ9,KCNN1,KTN1,MAT2A,MYL3,PCDH9,PDGFRA,RASGEF1B,SALL1,FBXO11,SLC8A3,SLC9A5,SLN,SNAP25,SOX5,ARHGAP26,TCF4,SATB2,TRPS1,FXR1" Transcription Factor Binding Site V$EVI1_04 V$EVI1_04 8.78E-03 1.00E+00 2.11E-02 1.48E-01 55 194 "CSMD3,MTUS1,SEMA6A,CASK,PTCH2,SLC4A4,PRMT9,LDB2,NRXN3,CSNK1E,CHRDL1,DMD,EDN1,HIPK3,EIF5,ELAVL4,EMX2,EYA1,ZIC4,FGF12,FGF13,CYP46A1,PPARGC1A,KIRREL3,GJB1,GRIK3,GRM1,IL1RAPL1,ADAMTS6,HAS2,HPSE2,NIM1K,LRRTM3,LRRTM1,MBNL1,MEIS2,MID1,CTNNA3,NCAM2,NEUROD2,OPCML,PDE4D,PDZRN4,RORB,SOX5,LMO3,POGZ,ST5,CLASP1,RALYL,PCDHA5,TPM1,P2RY12,ZIC1,SLC17A6" Transcription Factor Binding Site V$OSF2_Q6 V$OSF2_Q6 9.29E-03 1.00E+00 2.23E-02 1.56E-01 59 211 "PHF12,ATP2A2,NOL4,ATP6V0A1,ADGRB2,MTMR3,SPAG9,CHN1,CLCN3,NGEF,HAPLN1,CSNK1G3,DMPK,KLHL5,ELAVL2,ELAVL3,SRRM1,ZIC4,FGFR1,MEX3B,DACH2,FERMT2,GPD1,ADAMTS8,IL1RAPL1,HP,KCNMA1,SMAD9,MSRA,NCAM1,NEUROD1,NEUROD2,NKX2-2,OMG,PCSK5,KCTD15,PURG,PRRX1,ZNF532,SGK1,SLC6A9,SLC8A1,SOX2,LMO3,TAF6,TCF4,TCF12,SYNE1,PCDHA1,SIRT1,HEY1,WRN,ZIC1,CELF4,DPYSL5,RGMA,PRDM10,FAM13C,JMJD1C" Transcription Factor Binding Site V$TAL1BETAITF2_01 V$TAL1BETAITF2_01 9.42E-03 1.00E+00 2.25E-02 1.58E-01 58 207 "ACLY,C1QTNF4,ABCD2,RASL11B,B3GALT2,MAP7,FMNL3,CD81,NUMBL,ARHGAP22,HECTD1,PHACTR3,DAPK1,ELMO1,DMD,DNAH9,MBNL2,ELAVL4,RCAN2,EFS,CLVS1,ATP8A1,FGF13,FLNC,SORBS1,STAG2,GFRA1,GPD1,NXPH3,GABARAPL2,MARK1,MID1,MSI1,NAP1L1,RCOR2,NEUROD2,NHLH1,NPR2,PAK3,PDE1A,SERPINI1,KCTD15,SH3KBP1,GTDC1,RGS3,SEMA6D,ZNF821,SLN,SOX5,KDM4C,FGD4,PLCB1,TAC1,TCF12,NSD1,ZFPM2,PRDM8,FBXO36" Transcription Factor Binding Site V$SRY_01 V$SRY_01 9.48E-03 1.00E+00 2.26E-02 1.58E-01 46 158 "ANK3,SEMA4G,ATP2A2,B3GALT2,CACNA1E,LGI1,CRY2,DLG2,SH3GLB1,EIF4G2,ING4,ELAVL4,EMX2,DPYSL4,SORBS1,GFRA1,ATF7,KCNA1,STMN1,HECTD2,CTNNA3,MXI1,NBL1,NCAM1,NFIA,OPCML,PAX6,PDE3B,PIK3C2A,PIK3CD,PDZRN4,PRRX1,RFX4,KIRREL1,SOX6,CPEB3,CLSTN1,ATF7IP,SOX5,NMNAT2,LMO3,TAL1,TCF7L2,CA14,NAV3,JMJD1C" Transcription Factor Binding Site V$EN1_01 V$EN1_01 9.92E-03 1.00E+00 2.35E-02 1.65E-01 29 91 "ANK2,LINC00173,FGF17,MAP4K4,CREM,RGS6,SIPA1L1,ELN,ERBB4,EFEMP1,FHL1,GAP43,GRIA1,IL1RAPL1,LMO1,MITF,NKX2-2,NOS1,PAX6,PCDH9,PDGFRA,PEX2,RPL38,RTKN,SLC6A9,KDM4D,PLCB1,TCF4,UBE2H" Transcription Factor Binding Site V$ATF4_Q2 V$ATF4_Q2 1.06E-02 1.00E+00 2.50E-02 1.75E-01 57 204 "NDRG2,CDC14B,NOL4,CDK5R1,BSN,USP2,SYNGR3,ADGRG1,NRXN2,SULT4A1,PHACTR3,DCTN1,SV2B,HS3ST2,MBNL2,EIF4G1,FGF14,ZMYND15,FLNC,SORBS1,GABRA1,GNAS,GPM6B,ADAP1,GRM3,ELOVL5,ICA1,KCNN2,SMAD1,ZFYVE27,SCAMP5,MPP2,NF1,NPTX1,OGDH,PAH,PAK3,PCDH9,PDE4D,PENK,PNMA3,PKIA,PSD,RBBP8,RFX5,ROM1,SGK1,KDM3A,ZNF423,C11orf87,TAB2,NR2E1,DAAM2,TPM4,UBE2H,XPO1,SMARCAD1" Transcription Factor Binding Site TGANTCA_V$AP1_C TGANTCA_V$AP1_C 1.07E-02 1.00E+00 2.50E-02 1.75E-01 221 919 "CSMD3,NDRG2,ADCY8,GALNT13,AXIN2,SLC24A4,AP2A2,GPR158,KLHL13,CASKIN1,ANK3,ANXA7,ALS2,APP,PRX,CASK,ARNTL,ASPH,RASL11B,ATP2A2,ATP6V0A1,ADAM15,BACH1,NRP2,BTK,JAZF1,CACNA1A,DDR1,CALB2,DIRAS1,SPAG9,USP2,P2RX6,CBFA2T2,ARHGEF2,DCLK1,ADGRG1,CHRM1,KMT2C,NRXN3,ZFYVE9,NRXN1,MAGED1,ZFP28,CREB5,CSF1R,SIPA1L1,CNTNAP2,ST18,DOCK4,HDAC9,ARHGAP32,SNPH,DGKB,SCRN1,GIT2,PITPNC1,DCT,HEPH,C2CD2L,GSDME,SV2A,AK5,DLG4,DLX1,DMD,DMPK,HS3ST2,USP3,DRP2,RCAN1,DTNB,DYRK1A,EDN3,ATL1,EEF1A2,EIF4G1,ELAVL2,ENO2,EPB41L1,RCAN2,RTN3,EYA1,F3,CLVS1,ACSL4,TUBB4A,FGF1,FGF11,FGF12,FGF13,UBE2E3,HPCAL4,FLNC,DCTN2,ATP6V1H,ARPP21,NEK6,MYOZ2,MSTN,GFAP,GFRA1,PCDH17,PPARGC1A,KIRREL3,LYVE1,RUNDC3A,GLI2,RAB30,PCSK1N,GPM6A,LPAR4,STMN2,GRIA1,PLCD4,AP4S1,MAP4K5,SYNPO,AGBL5,RBPJ,ZNF385B,LRRTM3,JAK2,KCNA2,KCND1,KCNH2,KCNK1,MAP2,MAP4,MARK1,MDFI,LRP1B,SHC3,MITF,GIT1,MSI1,MT3,NASP,NDP,NEFH,NRDC,OLR1,OMG,ZNF827,KCNK10,PCDH9,PDE4D,PDE1B,PDGFRA,PFKFB2,PFKFB3,CDK14,NLGN3,SNX10,PKM,PLCD1,PLEC,SLC25A23,PDZRN4,PMP22,STRN3,PPP2R2B,PPP2R2C,LRRN3,PRKCG,MAPK3,MAPK10,MASP1,BCAS3,PTH1R,PTPRN,PEX5,RGS3,NUDT11,MYH14,ROM1,RPS20,RTN1,MAPK12,SGK1,ARX,SMTN,PKNOX2,SLC11A1,NAPB,LGI3,RIMS1,SNAP25,SNCB,KDM3A,ZHX3,SRPK2,TAB2,SSTR2,NCDN,MPRIP,ELOVL4,STX1A,GSE1,KLHL7,NUDT10,SYN1,SYP,COBL,ANKRD28,TAC1,POPDC3,MCF2L,PDLIM2,FBXW11,TBL1X,TCF12,NSD1,TPM2,TUBA3FP,UBE3A,VGF,TRIM9,SLC38A1,SEMA3B,RTN4" Transcription Factor Binding Site V$STAT5A_04 V$STAT5A_04 1.07E-02 1.00E+00 2.50E-02 1.75E-01 46 159 "ACTN1,CSMD3,OSBPL6,APBB2,NOL4,LDB2,FEZ2,DMD,DUSP9,ELAVL2,FGF12,FGF14,PPARGC1A,NTNG2,GPR34,GRIA1,IGF1,ZNF385B,MBNL1,MITF,MYH3,NCAM1,SLCO1C1,NKX2-2,PBX1,ABCB1,SMOX,MAPK9,SYTL2,ANKHD1,PTPRD,RALGDS,DPF2,RORB,TNFRSF19,CXXC4,FNBP1,ARC,ANKRD28,ZFPM2,AP4E1,TRPS1,SSBP2,P2RY12,SCG2,JMJD1C" Transcription Factor Binding Site V$STAT5A_02 V$STAT5A_02 1.07E-02 1.00E+00 2.50E-02 1.75E-01 34 111 "NCKAP5,SRPX,BTK,BTRC,CACNB2,CREM,PPP1R16B,ELMO1,ERBB4,SYNCRIP,MPP6,GABRB1,GBX2,CYP46A1,GFAP,STARD3,GSN,ATOH8,HNF4G,MBNL1,KITLG,MITF,DDX25,PCDH9,PCSK2,ENPP2,PIK3R1,LRRN3,LAMA1,ZNF423,TAL1,MGRN1,ZNF384,ZNF184" Transcription Factor Binding Site V$LEF1_Q6 V$LEF1_Q6 1.11E-02 1.00E+00 2.57E-02 1.80E-01 61 221 "KCNH8,ABR,ARID1A,BCAR3,ABCD2,ARHGAP20,FGF17,NRP2,BMP7,CDK5R1,CACNA2D1,CHN2,HECTD1,IGDCC3,EDN3,KLHL5,ELAVL2,SEZ6,KATNAL1,ZIC4,TUBB4A,MEX3B,SYNCRIP,DPYSL4,SORBS1,GABRG2,GAP43,GDF1,NKD1,SCRT2,INSM1,KCND2,KIF5A,LIFR,SHC3,SESN3,NFYA,NRCAM,ODF2,PDE4D,PRRX1,RGS3,ZNF532,TNFRSF19,CNKSR2,PREX2,SOX5,SOX11,LMO3,THSD1,SYT11,ANKRD28,MCF2L,TCF7,TCF7L2,CLASP1,CA14,ZNF184,LRP8,PCBP4,SLC17A6" Transcription Factor Binding Site V$IK3_01 V$IK3_01 1.16E-02 1.00E+00 2.67E-02 1.87E-01 50 176 "ASIC1,ACTN1,SLITRK1,PCDH10,MRTFA,ANK3,PKP4,MADD,ADAM15,ADGRB3,FGF17,SYNPR,CHRNB2,HECTD1,MAP4K4,IGDCC3,CCDC3,DNAH9,MBNL2,EGR3,EPB41,FLNC,STAG2,GABBR1,GABRB1,DHRS4,STARD3,GNAO1,CLASRP,IL11RA,KCNA4,KCNH2,KIFC3,LIFR,MYT1,RCOR2,SERPINI1,PRRX1,PPP2R2B,PSD,RTN1,SALL1,SLC6A9,TAL1,NSD1,CHST8,VSNL1,XPO1,SLC30A3,CA10" Transcription Factor Binding Site V$TTF1_Q6 V$TTF1_Q6 1.16E-02 1.00E+00 2.67E-02 1.87E-01 58 209 "NDRG2,ADCY6,PHYHD1,AQP4,ADGRB2,FGF17,PTBP2,CFL2,CNTN1,ZNF521,NRG2,PITPNC1,DCTN1,B3GAT3,DLX1,ELAVL4,CACNG2,ZIC4,DLC1,HPCAL4,FLT1,PCDH17,GPM6A,GRIK5,PTPRT,AP4S1,ICA1,DOCK7,SCRT2,LRRTM3,KCNH2,ZFYVE27,MAP4,STK32C,MXI1,RCOR2,NOVA1,NPPA,PCDHGC3,PCSK1,PHKG1,PLXNB1,STRN3,EPB41L4B,SYTL2,CRTAC1,ZNF532,RYR1,ARX,SLC6A7,NCDN,TCF4,PCDHAC2,HHIP,TPM2,ZIC1,PRDM8,GJC2" Transcription Factor Binding Site V$AP2_Q6 V$AP2_Q6 1.19E-02 1.00E+00 2.74E-02 1.92E-01 56 201 "ARID1A,PHF12,PPFIA1,GAS7,APLP1,SPTBN4,ARHGAP5,BSN,CRLF1,LHX2,COL11A2,CTNND2,MYADM,NYAP1,CNNM1,PLXNC1,RASGRP2,EPHB1,WAC,FGF11,ATP5PD,CELF1,STAG2,KAT7,GUCY1A2,NXPH3,ICA1,INSM1,KCNN2,MEIS2,RCOR2,HCN1,SMOX,SPATA6,PPP2R5E,CNNM2,RAP1GDS1,ZDHHC14,DUSP15,REV3L,CARF,SALL1,GALNT10,PPM1E,FBXO11,ATF7IP,CPEB4,SOX2,SP4,SPTB,CAMTA2,GSE1,SIRT1,UBTF,WNT7A,KLC2" Transcription Factor Binding Site YWATTWNNRGCT_UNKNOWN YWATTWNNRGCT_UNKNOWN 1.20E-02 1.00E+00 2.76E-02 1.93E-01 20 58 "ARNTL,ATP1A2,CA4,CTNND2,HDAC9,DMD,GNAO1,LINC01089,MAP2,ZDHHC8,PCDH18,PRRX1,RASGRF1,SLC1A7,CPEB4,SNAP25,CMTR2,HEY1,VLDLR,FBXO36" Transcription Factor Binding Site V$HFH1_01 V$HFH1_01 1.21E-02 1.00E+00 2.76E-02 1.93E-01 55 197 "SLC12A5,C1QTNF3,CASK,LINC00173,ASPA,ATP2A2,CACNA1D,CAPN3,ARHGEF2,LGI1,TOGARAM2,CREB5,SNCAIP,CSNK1G3,RASSF2,DMD,DPYSL2,ELAVL2,EMX2,EZH1,EFEMP1,IP6K2,NSG2,STAG2,SALL3,MSL3,GRIK2,GRIK3,KLF12,SMAD1,SCG3,NCAM1,NLGN3,PIK3C2A,PDZRN4,ING3,POU3F4,PPP2R2B,MAPK3,MAPK10,PROX1,SEMA6D,SCN4B,SHANK2,TRERF1,SOX2,NCDN,ANKRD28,SATB2,RALYL,ITGB3BP,HHIP,C5orf64,UBE2H,PLPPR2" Transcription Factor Binding Site V$NKX25_01 V$NKX25_01 1.22E-02 1.00E+00 2.77E-02 1.94E-01 32 104 "ASIC1,AQP6,RASL11B,DDR1,CFL2,MAP4K4,CREB5,DCTN1,DLX1,EGFR,STARD3NL,ZIC4,STAG2,PCDH17,GGT7,GPM6A,TLX1,LRRTM1,MBP,MEF2C,CTNNA3,NKX2-2,PAX6,PPP3CC,CRTAC1,ELP2,LRRC4,TCF4,PCDHAC2,TPD52,PRDM8,PCBP4" Transcription Factor Binding Site V$MEIS1BHOXA9_01 V$MEIS1BHOXA9_01 1.24E-02 1.00E+00 2.82E-02 1.97E-01 35 116 "ACTN2,CSMD3,UNC79,ATP2B3,NOG,CHN2,SYNPR,DMD,ZIC4,OLFM1,TBR1,GABRG2,GBX2,GNAO1,GRM8,HNF4G,ZIC5,INSM1,KLRC2,KLRC3,MBNL1,NOVA1,PCSK2,CDK14,PIK3R1,PTH1R,RASGRF1,NMNAT2,LMO3,TBL1X,KLHL4,ITGB3BP,TPM2,EIF4ENIF1,AMOT" Transcription Factor Binding Site V$P53_DECAMER_Q2 V$P53_DECAMER_Q2 1.26E-02 1.00E+00 2.85E-02 1.99E-01 59 214 "SLITRK1,ADD3,SPTBN4,SLC4A4,NOL4,BTK,CACNA1A,CACNB2,KALRN,HIP1R,TJP2,DNAJB5,ARHGEF6,AKAP6,WHRN,IFFO1,PITPNC1,DLG2,DMD,USP3,ABCC5,EGFR,BSCL2,ETV1,CACNG2,FGF11,MSTN,GNG3,AP4S1,TLX1,SHISA6,LRRTM3,MXI1,NCAM2,NDP,CNOT4,NTRK3,PHKG1,SMOX,STRN3,PRRX1,ING3,PTAFR,PTH1R,PXK,PTPRG,SEMA6D,SLC1A3,PREX2,DHX30,SLC6A9,EFHD1,TRERF1,KDM4C,ERBIN,ST5,FGD4,DOCK9,FLRT1" Transcription Factor Binding Site V$GNCF_01 V$GNCF_01 1.27E-02 1.00E+00 2.86E-02 2.00E-01 21 62 "SLITRK1,NOG,SOCS5,CTNND2,KIAA0586,DMD,TUBD1,KCNMB2,MRVI1,FLT1,GK,GNAO1,GPR155,MEF2C,MYL3,SLCO1C1,ZNF532,ERBIN,STAC2,SEZ6L,TRPS1" Transcription Factor Binding Site RNTCANNRNNYNATTW_UNKNOWN RNTCANNRNNYNATTW_UNKNOWN 1.30E-02 1.00E+00 2.90E-02 2.03E-01 18 51 "MTUS1,NOL4,NRXN1,CHRDL1,USP3,ELAVL4,EMX2,GPM6B,CDH20,MAP2,ZNF827,PDZRN4,SRPK2,SULF2,TAC1,HEY1,CELF4,ST7" Transcription Factor Binding Site V$GATA6_01 V$GATA6_01 1.30E-02 1.00E+00 2.91E-02 2.03E-01 57 206 "ADCY6,SPOP,BIN1,LRCH2,BSN,CACNB2,CDH2,NOG,HS3ST5,CREB5,CS,GREB1,CDON,PHC2,ELAVL4,ENO2,EYA1,SORBS1,GABRA2,GATM,GBX2,PPARGC1A,PTGDR2,KLF12,HPSE2,LIMS1,LSAMP,GPR155,MEF2C,MID1,BCO1,CTNNA3,DDR2,SNTG1,PCDH9,PDE3B,PDGFRA,PRRX1,PKIA,MASP1,PTPRG,RGS3,RORB,PPM1E,SOX5,KDM3A,LMO3,EPB41L3,TACC1,PUM2,ZFPM2,ITGB3BP,TRPS1,UBE2H,VSNL1,CELF4,DOCK8" Transcription Factor Binding Site V$EGR_Q6 V$EGR_Q6 1.35E-02 1.00E+00 2.99E-02 2.09E-01 61 223 "ADCY8,PHF12,PRX,CACNA1A,CACNA1B,CACNA1D,SYT6,CBLN1,REPS2,CDH2,KCNAB3,NUMBL,DNAJB5,RAB26,SLITRK5,PPP1R16B,MATR3,C2CD2L,AK5,CHRDL1,OLIG1,EFNB3,CELSR3,ABI2,GPHN,GABRG2,GAD1,GBX2,PCDH17,INSM1,KCNB1,KCNJ10,KCNN2,MSI1,NEUROD2,NKX2-2,NRDC,PCSK2,SH3KBP1,PPP3CA,PPP3CB,PSD,EML5,ACER3,SLC9A5,SP4,SPTB,LMO3,RGL1,ICAM5,TPM4,TSC2,UBE3A,UBTF,OSBP2,VLDLR,CELF4,FSTL5,PRDM10,FBXO36,NETO1" Transcription Factor Binding Site V$IK1_01 V$IK1_01 1.37E-02 1.00E+00 3.03E-02 2.12E-01 60 219 "ABR,ACTN1,ARID1A,SLITRK1,SEMA6A,MRTFA,DOC2A,PI16,ARHGAP5,ATP1A3,ADGRB3,FGF17,CD86,SNCAIP,DLX1,HS3ST4,ABCC5,ZIC4,FGF13,NEK6,TUBGCP4,PCDH17,DHRS4,RND1,GPM6A,CLASRP,IL1RAPL1,GUCY1B1,PACSIN2,ZIC5,LIFR,SHC3,MMP16,MSI1,NDP,NNAT,PURG,MED1,PPP2R5E,PSD,LAMA1,CRTAC1,RFX4,SALL1,PREX2,NAPB,SP4,SMOC1,NEK4,PHLDB1,COBL,NSD1,ZFPM2,TRPC1,EIF4ENIF1,UBE2H,VGF,VSNL1,WRN,KCNAB1" Transcription Factor Binding Site V$GATA1_02 V$GATA1_02 1.49E-02 1.00E+00 3.27E-02 2.29E-01 55 199 "ADCY6,ADGRF5,SEMA6A,BIN1,NRP2,CACNB2,CAST,PLEKHB1,RAB3C,MAP4K4,HS3ST5,CREM,CREB5,CRY2,CS,HDAC9,DMD,CDON,ELAVL2,ING4,ELAVL4,EMX2,FGF13,GPM6A,EML4,HNMT,TLX1,ZNF385B,KCNJ10,KCNK3,LIFR,GPR155,MBNL1,MITF,CTNNA3,MYH6,MYT1,PDGFRA,CCSER2,SMOX,SCHIP1,SH3KBP1,MASP1,RFX4,SATB1,FBXO11,SLC8A3,SNCA,SOX11,KDM3A,NCDN,SYN1,SATB2,UBE2H,CELF4" Transcription Factor Binding Site V$NKX62_Q2 V$NKX62_Q2 1.49E-02 1.00E+00 3.27E-02 2.29E-01 55 199 "SLITRK1,C1QTNF3,AQP6,ATP2A2,NOL4,COL11A2,ELMO1,RHOBTB1,DLX1,DMD,RCAN1,WDPCP,ELAVL4,EYA1,ZIC4,FGF13,MSTN,STMN2,SCRT2,LRRTM3,ITGA7,KCNN3,ADAM11,MEF2C,MITF,MYT1,NEUROD2,NFIX,NKX2-2,OGG1,PDGFRA,ABCB1,PDZRN4,PTH1R,GAL3ST4,FIGN,PRIMA1,EMID1,LRFN5,LRRTM4,BTBD3,SLN,SOX15,UNC5B,LMO3,EPB41L3,ADAMTS17,ZFPM2,C5orf64,KAT6B,TNR,FLRT1,XPO1,ZIC1,JPH3" Transcription Factor Binding Site V$CIZ_01 V$CIZ_01 1.53E-02 1.00E+00 3.35E-02 2.34E-01 53 191 "ASIC2,PKP4,AQP4,SEMA4G,CAST,NRG2,SNCAIP,TBC1D5,RIMS3,SPOCK2,PITPNC1,DMTF1,ELAVL2,CACNG3,ZIC4,FGF14,FOXF2,TUBGCP4,GLS,PCDH11X,GRM3,KLF12,HPSE2,TLX1,KIT,LAMP2,MBNL1,MEIS2,NCAM1,NDP,NFIX,NKX2-2,CDK18,PDE4D,CCSER2,PLP1,PRRX1,SYTL2,GAL3ST4,RFX4,ARX,SLC8A3,WDTC1,TRERF1,LMO3,ADAMTS17,SYN2,TBL1X,TCF4,ZFPM2,TMPO,ZIC1,CAB39L" Transcription Factor Binding Site V$AP1_Q6 V$AP1_Q6 1.53E-02 1.00E+00 3.35E-02 2.34E-01 59 216 "NDRG2,AXIN2,ADORA2A,AP2A2,ANXA7,CASK,BTK,DIRAS1,P2RX6,ST18,SCRN1,PITPNC1,C2CD2L,AK5,DMPK,HS3ST2,EEF1A2,RCAN2,FGF12,FLNC,DCTN2,NEK6,GFAP,LYVE1,RUNDC3A,RAB30,RBPJ,ZNF385B,KCNA2,MAP2,MAP4,MARK1,MDFI,SHC3,NDP,NEFH,OLR1,OMG,KCNK10,PCDH9,CDK14,PLCD1,PLEC,MAPK3,PTPRH,PTPRN,ROM1,SLC9A5,RIMS1,SNCB,KDM3A,NCDN,MPRIP,COBL,FBXW11,TCF12,TUBA3FP,VGF,RTN4" Transcription Factor Binding Site V$FOXO3_01 V$FOXO3_01 1.56E-02 1.00E+00 3.38E-02 2.37E-01 52 187 "BIN1,LINC00173,BCL7A,CACNA2D1,SYT6,LDB2,CDK11B,AP4M1,CFL2,ZNF521,SNCAIP,DOCK4,MBNL2,TENM1,EZH1,CACNG2,FGF12,MPP6,SALL3,ARFIP1,GFRA1,BRD8,IL1RAPL1,HAS2,NXPH3,KLF12,MBNL1,MEIS2,KITLG,NFIX,NNAT,NTRK3,PAX6,ENPP2,CDK14,RETREG1,PCDH18,PDZRN4,POU3F4,MAPK10,ARID4A,RFX3,ABTB1,NMNAT2,LMO3,TAL1,TBL1X,TJP1,C5orf64,UBE2H,PHTF2,JMJD1C" Transcription Factor Binding Site V$PXR_Q2 V$PXR_Q2 1.56E-02 1.00E+00 3.38E-02 2.37E-01 58 212 "TTYH1,NDRG2,MAP4K3,APP,ARNTL,CDK13,ADAM15,CACNA1G,CDH10,NRXN3,MAP4K4,CCDC151,CABP1,CREB5,ATRNL1,SCRN1,NTM,DMD,USP3,MBNL2,PLEKHA1,KCNMB2,GPHN,FGF11,FGR,AKAP3,GAP43,GLYR1,PLCD4,GRIK3,IL1RAPL1,NXPH3,IL11RA,LRRTM3,ITIH2,LMO1,SMAD1,MEIS1,MEIS2,MITF,MPP2,NEUROD1,HCN1,NLGN3,PRRX1,SYTL2,KLHL11,ZNF532,ROM1,EMID1,SLN,STAC2,SEMA4A,TAL1,NR2C2,CA14,ZNF70,JMJD1C" Transcription Factor Binding Site V$HIF1_Q3 V$HIF1_Q3 1.58E-02 1.00E+00 3.41E-02 2.39E-01 51 183 "DSCAML1,SLC12A5,SPOP,AMPD2,PHF12,USP37,ARNTL,ZBTB10,ATP1B3,FGF17,RAB33A,PPT2,MICAL2,DSCAM,ABI2,ASB3,EIF4G1,EML1,FGF11,DOT1L,GPM6B,SHISA6,INSM1,LRRTM1,KTN1,STMN1,MEF2C,RCOR2,ZNF827,KCTD15,ING3,EPB41L4B,NXPH1,PSD,RFX5,COPZ1,PPM1E,FAM214B,SLC6A1,SLC12A4,SORCS3,SNCB,KDM4B,SOX2,KDM3A,EMC1,HIF3A,ZIC2,SLC26A10,LRP8,NAV2" Transcription Factor Binding Site V$STAT5A_03 V$STAT5A_03 1.59E-02 1.00E+00 3.42E-02 2.39E-01 57 208 "ASIC2,ACTN1,KLHL13,BCAR3,STK33,ATP2A2,ADAM23,MAP4K4,ZNF385A,CREB5,SNCAIP,PHACTR3,SLITRK5,HEPH,KLHL3,SV2A,DPYSL2,RCAN1,PLEKHA1,FGF11,FGF13,FGR,MEX3B,PCYOX1,FLNC,FLT1,DCTN2,DACH2,GABRG1,PCDH17,IL1RAPL1,HPCA,ITGA7,KCND3,KCNJ16,KCNN3,STMN1,KITLG,MYT1,NEUROD2,NFE2L2,PCDH8,PDE3B,LRRN3,PSMA6,FBXW7,SATB1,SCN2B,EFHD1,FAIM2,TAB2,ROBO3,TCF4,TPM3,TRPS1,UBE2H,CELF4" Transcription Factor Binding Site V$PAX4_01 V$PAX4_01 1.69E-02 1.00E+00 3.62E-02 2.53E-01 59 217 "AP1B1,PHF12,DGKZ,NAE1,CACNA1D,GPR37L1,RAB33A,NRXN1,DNAJB5,CNTFR,C1QL2,MAML1,DLG3,DNM1,HS3ST2,PLEKHA1,MEX3B,SYNCRIP,C1QL1,GK,GRIK1,IL1RAPL1,PSIP1,SMAD1,ZFYVE27,MAPT,MXI1,NRDC,NTRK3,ZNF827,PBX1,PDE4D,PIK3CD,PDZRN4,MAPK10,PTPRG,RBBP6,STX1B,SALL1,GALNT10,EFHD1,SORCS3,TRERF1,SP4,SPTAN1,NCDN,GSE1,ARHGEF12,HIF3A,DAAM2,TPM1,UBTF,VGF,KLC2,XPO1,ZIC2,SEMA3B,FBXO36,TIGD6" Transcription Factor Binding Site RYCACNNRNNRNCAG_UNKNOWN RYCACNNRNNRNCAG_UNKNOWN 1.70E-02 1.00E+00 3.63E-02 2.54E-01 19 56 "ASIC1,CALB1,LDB2,CHRDL1,EGR3,EMX2,CLVS1,FGF13,FYB1,LINC01089,MEF2C,NEUROD2,PPP3CB,ARX,FBXO11,PHLDB1,AHCYL2,C5orf64,TPM3" Transcription Factor Binding Site V$CDP_01 V$CDP_01 1.70E-02 1.00E+00 3.63E-02 2.54E-01 24 75 "CASKIN1,CAST,WDPCP,PHC2,PIPOX,FGF12,FGF13,FOXF2,FYN,STMN2,SCRT2,ADAM11,MEIS1,MITF,MN1,NFIX,NKX2-2,ACER3,SMOC1,SULF2,TAC1,RALYL,STMN4,SLC17A6" Transcription Factor Binding Site V$EVI1_03 V$EVI1_03 1.85E-02 1.00E+00 3.93E-02 2.75E-01 17 49 "ASIC2,SORCS1,CACNA1D,HS3ST5,CREB5,IPCEF1,DMD,MBNL2,PPARGC1A,PTGDR2,LMO2,CTNNA3,SRPK2,NCDN,VAMP1,ZFPM2,TSC1" Transcription Factor Binding Site CTGRYYYNATT_UNKNOWN CTGRYYYNATT_UNKNOWN 1.96E-02 1.00E+00 4.15E-02 2.91E-01 18 53 "ASIC2,CSMD3,NRP2,CACNB2,CABP1,COL9A1,PHYHIP,CCDC3,DMD,CSPG5,GRIA1,IL1RAPL1,NTRK2,PIK3R1,SMOX,CNKSR2,SOX10,NCDN" Transcription Factor Binding Site V$NMYC_01 V$NMYC_01 2.03E-02 1.00E+00 4.26E-02 2.98E-01 59 219 "SLC12A5,ARHGAP20,AMPD2,SEMA7A,B3GALT2,ADGRB2,CACNA1D,MAP7,USP2,CHRM1,NRXN1,SNCAIP,SOCS5,KIAA0586,CTIF,COPS7A,DLX1,EIF4G1,EN2,EPB41,ENPP6,ETV1,DLC1,TESK2,FGF11,FOXO3,NOP56,CELF1,IQGAP2,RAB30,GPD1,IL1RAPL1,HRH3,HPCA,SCRT2,GIT1,RCOR2,NEUROD2,NKX2-2,PFKFB3,NXPH1,SH3KBP1,PRKCG,RBBP6,SYBU,FAM214B,SLC9A5,KDM3A,SEPT3,ADAMTS17,HHIP,ZFP91,SEZ6L,TPM2,WBP2,CA14,VGF,STMN4,KAT6A" Transcription Factor Binding Site V$GATA3_01 V$GATA3_01 2.03E-02 1.00E+00 4.26E-02 2.98E-01 54 198 "ASIC2,CSMD3,BIN1,CRLF1,RAB3C,CREB5,HDAC9,DMD,EDN1,ELAVL4,DMTN,SRRM1,ERBB2,CLVS1,EFEMP1,FER,SYNCRIP,SORBS1,ATP2C1,IGF1,ZNF385B,KCNK3,LMO1,MAP4,MBNL1,MEIS2,MITF,NRGN,GPR85,PENK,NLGN3,PRRX1,SH3KBP1,MASP1,APTX,RGS12,SALL1,MYO18A,FBXO11,SLC8A3,SNCA,SOX5,SOX10,LMO3,NCDN,TTBK2,SYN1,TACC1,SATB2,TF,PRR18,VGF,VSNL1,SH3GLB2" Transcription Factor Binding Site V$HMGIY_Q6 V$HMGIY_Q6 2.06E-02 1.00E+00 4.30E-02 3.01E-01 53 194 "NDRG2,SLITRK1,PCDH10,GAS7,LINC00173,ATP1B3,STX16,PTBP2,USP2,NEURL1,CDC27,CTNND1,COPS7A,EIF4G1,CALCRL,WAC,ZIC4,TACC2,DLL3,GAD1,LYVE1,GRIK1,HAPLN2,SHISA6,RBPJ,INSM1,KLRC2,KLRC3,STMN1,HECTD2,MBNL1,TM6SF1,MEIS1,STK32C,MYBPC1,NCAM1,NFIX,NOS1,NTRK3,PDE4D,KCTD15,PPM1B,MAPK4,PTHLH,LRRTM4,SH3BGR,SLC1A7,SOX5,LMO3,ANKRD28,ANKRD12,ZIC1,KCNAB1" Transcription Factor Binding Site V$NFAT_Q4_01 V$NFAT_Q4_01 2.07E-02 1.00E+00 4.30E-02 3.01E-01 58 215 "NDRG2,SLITRK1,PCDH10,OGT,GAS7,PPP4R4,CASK,ZBTB10,ATP1B3,USP2,KMT2C,TJP2,MAP4K4,FHL5,CNTFR,CREB5,CHRDL1,CALN1,MBNL2,ETV1,ZIC4,FGF14,ABLIM2,RAPGEF6,PCDH17,C1QL1,KIRREL3,GSN,IL1RAPL1,PACSIN2,LIMS1,MITF,HS6ST3,NDP,PAK3,PDE3B,PDZRN4,MAPK4,PTHLH,PTPRZ1,DPF2,RGS3,SMPD3,SLITRK3,SLA,SNAP25,TRERF1,SOX3,SOX5,SRPK2,ANKRD28,SYT4,KLHL4,DICER1,TIAM1,TPM3,TRPS1,XPO1" Transcription Factor Binding Site V$POU3F2_01 V$POU3F2_01 2.07E-02 1.00E+00 4.30E-02 3.01E-01 26 84 "ASPA,ADGRB3,CDH10,SYNPR,RAB3C,CSNK1G3,HDAC9,SALL3,GPM6A,LRRTM3,MAP2,PPM1L,MYBPC1,NOVA1,KCNK10,KCTD15,PDZRN4,PRRX1,PTHLH,FBXO11,ZNF423,SPTB,LMO3,STAC2,NSD1,VGF" Transcription Factor Binding Site GCCNNNWTAAR_UNKNOWN GCCNNNWTAAR_UNKNOWN 2.10E-02 1.00E+00 4.36E-02 3.05E-01 35 120 "ARID1A,NDRG2,EPB41L5,ASGR1,LDHD,CAMK2D,KYAT1,DGKI,RAB33A,DMPK,ABCC5,ELAVL4,EN2,FYN,JPH4,PPARGC1A,EML4,HPSE2,SFXN5,MID1,MITF,MN1,MPP2,NPTX1,OPCML,KCTD15,PTPRG,PEX5,RFX4,SOX5,SIK3,CA14,KLC2,CELF4,DPF3" Transcription Factor Binding Site V$AHRARNT_01 V$AHRARNT_01 2.11E-02 1.00E+00 4.37E-02 3.05E-01 34 116 "SLITRK1,CNTNAP1,JAZF1,CAMK2D,HECTD1,RGS6,SPOCK2,PITPNC1,CNNM1,EGR3,ELAVL2,ELAVL4,SEZ6,ACSL4,MEX3B,IP6K2,GABRA1,PCDH17,GHR,GNAO1,NR3C1,GRM7,INSM1,MBNL1,MOV10,MXI1,NEUROD2,PAX6,NLGN3,EPB41L4B,SGK1,TACC1,TCF7L2,USP1" Transcription Factor Binding Site V$LEF1_Q2 V$LEF1_Q2 2.25E-02 1.00E+00 4.63E-02 3.24E-01 48 174 "ARID1A,ADD3,SORCS1,SYT13,AMPD3,ANK3,SEMA4G,PTCH2,ADGRB2,CACNB2,ZFYVE9,CREM,CTNND1,SPOCK2,SV2A,EIF4G2,ELAVL4,BSCL2,MRVI1,SORBS1,AP4B1,AHCYL1,GFRA1,RAB30,GNG3,LRRTM3,LMO1,MOV10,RCOR2,NPPA,DDR2,PAX6,PRRX1,PROX1,RET,CYB561D1,SOX6,SLC6A9,KBTBD4,NCDN,RGL1,TCF7L2,TMEM9,TLL2,PRDM2,LRP8,NAV2,SLC17A6" Transcription Factor Binding Site GATAAGR_V$GATA_C GATAAGR_V$GATA_C 2.28E-02 1.00E+00 4.68E-02 3.28E-01 66 250 "ASIC2,ADD3,BIN1,B3GALT2,NRP2,BTRC,CA4,SPAG9,NRXN3,PPT2,HS3ST5,CREB5,CS,CTNND1,HEPH,DMD,DYRK1A,EDN1,ELAVL4,ENO2,DMTN,ETV1,EYA1,GABBR1,GATM,PPARGC1A,PTGDR2,HPSE2,ZNF385B,KHK,LMO2,GPR155,MEF2C,MEIS2,MID1,MITF,CTNNA3,MYH6,MYH7,MYT1,NFIA,CDK14,CCSER2,PKIA,MASP1,FIGN,ROBO1,PLPPR3,SALL1,SATB1,TNFRSF19,PPM1E,MYO18A,SPHKAP,RIMS1,SOX5,SOX10,KDM3A,ZHX3,TAB2,NCDN,GSE1,TACC1,NPL,TRPS1,PRR18" Transcription Factor Binding Site V$CREB_01 V$CREB_01 2.31E-02 1.00E+00 4.73E-02 3.31E-01 57 212 "SLC25A25,ADCY8,PKP4,ALS2,NOL4,CAMK2D,SPAG9,KYAT1,SYNGR3,CDC42,CHGB,SULT4A1,CREM,PHACTR3,KCTD8,DCTN1,PARD6A,G3BP2,HS3ST2,RCAN1,MBNL2,ING4,EPB41,NCALD,DNAJC27,ZMYND15,FLT1,PPARGC1A,RUNDC3A,GPM6B,ADAP1,ELOVL5,KCNF1,ZFYVE27,SCAMP5,MITF,NF1,OGDH,PCSK1,PNMA3,MAPK10,RPRD1A,SNAP25,SPATA7,C11orf87,SST,SYT11,HHIP,NR2E1,DAAM2,RUSC1,UBE2H,VGF,ZNF184,SLC38A1,SCG2,NUP214" Transcription Factor Binding Site V$USF_C V$USF_C 2.33E-02 1.00E+00 4.75E-02 3.32E-01 61 229 "METAP1D,SLC12A5,ARHGAP20,AMPD2,SEMA7A,CACNA1D,SYT6,USP2,CHRM1,AKAP12,CRMP1,SNCAIP,MICAL2,SOCS5,CTIF,DRD1,CNNM1,EIF4G1,ENPP6,ETV1,RRAGB,FGF11,FGF14,HPCAL4,SYT3,RAPGEF6,GK,GPD1,IL1RAPL1,ZBTB49,HPCA,SCRT2,STMN1,MAT2A,GIT1,CNOT4,NPTX1,PAX6,NXPH1,SH3KBP1,BCAS3,SLC6A15,PBRM1,ARX,SYBU,FAM214B,SLC9A5,KDM3A,ELOVL4,ADAMTS17,SATB2,SIRT1,HHIP,ZFP91,SEZ6L,WBP2,RUSC1,CA14,VGF,LRP8,KAT6A" Transcription Factor Binding Site V$EGR2_01 V$EGR2_01 2.39E-02 1.00E+00 4.85E-02 3.39E-01 44 158 "AK2,DOC2A,USP37,CHRD,ATP2A2,ADGRB3,CAMK2A,LGI1,CLTC,HDAC9,PDCD6IP,DSCAM,ATL1,EGR3,PLXNC1,EPHB1,PPP1R1B,SYNCRIP,GABRA1,ARPP21,GUCY1A2,ITPKA,SMAD1,MAN2A2,NKX2-2,NRCAM,NRGN,PKD1,RBBP6,KCNIP2,SEC14L1,SH3GL3,FAM214B,SORCS3,RIMS1,SNAP25,SPTB,SSTR1,GSE1,RALYL,SIRT1,THRA,VGF,CELF4" Transcription Factor Binding Site WGTTNNNNNAAA_UNKNOWN WGTTNNNNNAAA_UNKNOWN 2.40E-02 1.00E+00 4.85E-02 3.39E-01 112 450 "ASIC2,ADARB2,KLHL13,ALK,CASK,ATP1A2,ADGRB3,WASF1,SYT6,LDB2,LGI1,NOG,FOXN3,CHN2,RAB3C,NRXN3,ARHGEF6,COL9A2,ZNF521,CREB5,HDAC9,KIAA0586,C2CD2L,DMD,HS3ST4,CALN1,SLC25A18,DRP2,EPHB1,ETV1,EYA1,ARMCX1,CLVS1,CHST15,FGF12,FGF13,FGFR1,ATP2C1,TPPP3,STAG2,GABRA3,GAD1,HBS1L,ARPP21,GBX2,GLS,PCDH11X,GRM8,ADAMTS6,ATOH8,HPSE2,KCNMA1,ARHGAP12,PACRG,MARK1,MBNL1,ADAM11,SHC3,MEIS2,MITF,CTNNA3,MXI1,NCAM1,NFIA,NOVA1,ODF2,ZNF827,PAX6,PCDH9,PCSK1,GPR85,CDK14,ANLN,PIK3R1,CCSER2,PCDH18,PDZRN4,PPM1B,PPP2R2B,PPP2R5C,PRKACB,OXR1,RDX,RFX3,RGS3,KLHL11,FBXW7,LRFN5,TNFRSF19,KIF13A,SP4,ZNF423,LMO3,SSTR1,LRRC4,GSE1,SYNE2,FBXW11,TCF4,RALYL,NSD1,ARHGEF12,TEK,NR2E1,SSBP2,FLRT2,XPO1,CA10,PRDM10,JMJD1C,ZNF248,DPF3" Transcription Factor Binding Site V$ETF_Q6 V$ETF_Q6 2.40E-02 1.00E+00 4.85E-02 3.39E-01 26 85 "ARID1A,CDC7,CACNA1E,CAMK2G,ZFYVE9,EFNA3,SRRM1,WAC,HPCAL4,USP21,GRIK3,ZNF496,KCND3,NFIA,SPATA6,PPP3CB,PRKACB,RXRG,CLSTN1,EPC1,ZSWIM8,EMC1,UNC5B,RUSC1,LRP8,FAM13C" Transcription Factor Binding Site V$NFE2_01 V$NFE2_01 2.43E-02 1.00E+00 4.88E-02 3.42E-01 59 221 "METAP1D,NDRG3,DOC2A,ANXA7,BACH1,BCL7A,BTK,JAZF1,CALB2,P2RX6,CHN2,SCRN1,SV2B,HS3ST2,DRP2,ATL1,EEF1A2,EIF4G1,RCAN2,FGF11,FGF12,DCTN2,GAA,LYVE1,STMN2,SHISA6,KCNA2,MAP2,MAP4,MDFI,LRP1B,SHC3,MITF,NDP,OMG,PCDH9,PDE1B,NLGN3,SNX10,PLEC,PPP2R2C,MAPK10,PTPRN,ZCWPW1,NUDT11,ROM1,MAPK12,SLC11A1,SNCB,C11orf87,NCDN,NUDT10,SYN1,COBL,FBXW11,TBL1X,CLASP1,TUBA3FP,PAK5" Transcription Factor Binding Site V$SMAD4_Q6 V$SMAD4_Q6 2.45E-02 1.00E+00 4.90E-02 3.43E-01 54 200 "ARID1A,SLC12A5,PHF12,APBB1,ATP2A2,CACNA1G,CALM1,PTBP2,SLC25A14,USP2,LGI1,CHRM1,CLOCK,DCTN1,RCAN1,EPHB1,RTN3,CLVS1,CACNG3,AGAP2,DACH2,GDF1,KIRREL3,RUNDC3A,LOXL3,TMEM25,NXPH3,ELOVL5,AGBL5,HNRNPK,KCNN2,LMO1,MEF2C,MEIS2,NTRK3,PAK3,PDGFRA,KCTD15,PLEC,PPP2R2B,PPP3CA,PPP3CB,PRKCZ,RGS3,EPC1,C11orf87,SST,TCF4,TNS2,THRA,TRPS1,FLRT1,VGF,PCBP4" Transcription Factor Binding Site V$LFA1_Q6 V$LFA1_Q6 2.45E-02 1.00E+00 4.90E-02 3.43E-01 54 200 "ASIC2,ARID1A,SEMA6A,PHF12,CACNA1G,NEURL1,CLTC,ZNF385A,CRMP1,BOC,DCTN1,DLX1,DMPK,EFNA3,RBM12,RASGRP2,ETV1,RASL12,FLT1,NSG2,TBR1,OGA,GABRG2,GAD1,JPH4,GNAO1,CELF3,RBPJ,MOV10,SESN3,NACA,NRGN,PALM,PDYN,PLEC,PRRX1,PSD,ARID4A,RBBP6,DPF2,RFX4,ROM1,SALL1,CNKSR2,SOX5,NPAS3,C11orf87,NCDN,TAL1,TCF7,HIRA,LRP8,PRDM10,KCNAB1" Transcription Factor Binding Site V$PIT1_Q6 V$PIT1_Q6 2.50E-02 1.00E+00 4.97E-02 3.48E-01 53 196 "ASIC2,CSMD3,SLITRK1,KLHL13,SEMA7A,CASK,PTCH2,CAST,LDB2,NOG,CHN2,ZNF521,FEZ1,PHACTR3,DLG2,DSCAM,MBNL2,TENM1,ELAVL2,ELAVL4,EN2,EYA1,CACNG2,FGF13,FGFR3,NSG2,GBX2,GNAO1,IL1RAPL1,DOCK7,ZNF385B,STXBP5,MEIS1,MEIS2,MID1,MYBPC1,MIR4697HG,OPCML,PAX6,PCDH18,POU3F4,PPP2R2B,LGI2,SALL1,SCN3A,CPEB4,PCDHGB7,HHIP,THRA,RBFOX2,TPM1,PRDM8,FXR1" Gene Family 593 Fibronectin type III domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 2.77E-26 1.67E-23 1.67E-23 1.17E-22 75 161 "DSCAML1,UNC5A,LRFN2,ADGRF5,LRFN1,LRRC4C,IGDCC4,MYOM1,KALRN,MYOM2,IGFN1,JAM2,CNTN1,NRG2,IGDCC3,NECTIN3,LRIG1,BOC,DCC,MFAP3L,NTM,CDON,DSCAM,SPEG,FGFR1,FGFR3,FLT1,NPTN,CHL1,IGSF5,KIRREL3,ADGRA3,IL1RAPL1,LINGO1,IGFBPL1,NEGR1,L1CAM,LRRC4B,LSAMP,MAG,MDGA1,MYBPC1,NCAM1,NCAM2,LRIT2,NRCAM,NTRK2,NTRK3,IGSF11,OPCML,CNTN3,PRTG,PDGFRA,SDK2,LRRN3,MDGA2,PTPRD,ROBO1,KIRREL1,ROBO2,LRFN5,IGSF9B,PALLD,UNC5B,NFASC,LRRC4,ROBO3,UNC5D,CNTN2,OBSL1,LRRC24,TRIO,FSTL5,CADM2,ADAMTSL3" Gene Family 555 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 6.68E-22 4.03E-19 2.02E-19 1.41E-18 69 160 "ELFN2,DSCAML1,LRFN2,LRFN1,IGDCC4,ASTN1,MYOM1,KALRN,MYOM2,IGFN1,CRLF1,CNTFR,CNTN1,ABI3BP,IGDCC3,CSF3R,BOC,DCC,CDON,DSCAM,FSD1L,EBI3,EPHA5,EPHB1,PHYHIPL,CHL1,GHR,PTPRT,IL6ST,L1CAM,LIFR,MID1,MYBPC1,NCAM1,NCAM2,NRCAM,CNTN3,PRTG,SDK2,FSD1,LRRN3,PTPRB,PTPRD,PTPRG,PTPRH,PTPRO,PTPRZ1,ROBO1,ROBO2,EPHA10,LRFN5,FNDC3A,TRIM67,ATF7IP,IGSF9B,ANKFN1,NFASC,FNDC9,ASTN2,ROBO3,CNTN2,TEK,TIE1,TNR,FNDC5,FLRT2,FLRT1,TRIM9,ELFN1" Gene Family 1220 Membrane associated guanylate kinases|PDZ domain containing genenames.org 5.46E-17 3.30E-14 1.10E-14 7.68E-14 60 152 "LRRC7,PDZD4,APBA2,SHROOM2,PRX,CASK,MPDZ,MAGI1,TJP2,PICK1,WHRN,SIPA1L1,RIMS2,FRMPD4,TIAM2,MAGI2,PARD6A,DLG2,DLG3,DLG4,SHANK1,USH1C,PDLIM5,MPP6,SDCBP2,RAPGEF6,LNX1,PCLO,PARD3B,AFDN,MPP2,NOS1,SNTG1,PDZRN4,PTPN13,RGS3,RGS12,PPP1R9A,FRMPD1,MYO18A,MAGI3,CNKSR2,PREX2,RADIL,SHANK2,MAST1,RIMS1,PDZRN3,PDZD2,ERBIN,PDLIM2,ARHGEF12,TIAM1,TJP1,PARD3,SYNPO2,STXBP4,GORASP1,SNX27,GOPC" Gene Family 682 Zinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors genenames.org 5.50E-15 3.32E-12 8.31E-13 5.80E-12 69 206 "ABR,PLEKHG5,PLEKHH1,OSBPL8,FGD2,DGKD,SPTBN4,CADPS,KIF1A,DOCK11,ARHGEF7,BTK,ARHGEF2,PLEKHB1,ARHGAP22,ARHGEF6,SH2B1,OSBPL3,IPCEF1,APPL1,ARHGEF4,ARHGAP24,PLEKHM1,TIAM2,DNM1,DNM2,PLEKHA1,PLEKHO1,AGAP2,AGAP3,PSD2,GAB1,FERMT2,ADAP1,GRB10,ARHGAP12,ANLN,PSD,PLEKHB2,RASGRF1,RASGRF2,VEPH1,RTKN,SBF1,RASA3,SH3BP2,ITSN1,FERMT1,ASAP3,DOCK10,CNKSR2,DOK5,SPTB,KIF1B,MPRIP,PHLDB1,FGD4,ARHGEF9,MCF2L,DOCK9,PSD3,ARHGAP9,TIAM1,DOK6,OSBP2,PLEKHH2,VAV1,VAV2,SPATA13" Gene Family 20 Clustered protocadherins genenames.org 1.96E-11 1.18E-08 2.36E-09 1.65E-08 30 64 "PCDHGB4,PCDHGC3,PCDHB17P,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" Gene Family 722 Rho guanine nucleotide exchange factors genenames.org 5.15E-11 3.11E-08 5.19E-09 3.62E-08 30 66 "ABR,FGD2,ALS2,ARHGEF7,KALRN,ARHGEF25,ARHGEF1,ARHGEF2,NGEF,ARHGEF6,ARHGEF10,ARHGEF4,TIAM2,RASGRF1,RASGRF2,ARHGEF10L,ITSN1,PREX2,ARHGEF40,MCF2L2,FGD4,ARHGEF9,MCF2L,DNMBP,ARHGEF12,TIAM1,TRIO,VAV1,VAV2,SPATA13" Gene Family 694 Protein phosphatase 1 regulatory subunits genenames.org 2.20E-10 1.33E-07 1.90E-08 1.33E-07 55 181 "ELFN2,APC,SLC7A14,BCL2L2,NCOR1,AATK,PHACTR3,DZIP3,PPP1R16B,ZFYVE16,SPATA2,SACS,DLG2,DLG3,SH3GLB1,TMEM132C,PPP1R1B,FER,AHCYL1,PCDH11X,GPR12,GRM1,GRM5,GRM7,KCNA6,MAPT,KCNK10,PLCL1,PPP1R1A,HYDIN,SYTL2,PTK2,RYR1,CSRNP3,SFPQ,TRA2B,PPP1R9A,PREX2,SLC12A2,TMEM132D,MYO16,RBM26,STAU1,ANKRD28,WWC1,RPGRIP1L,RIMBP2,CSMD1,PARD3,TNS1,TP53BP2,TSC2,ELFN1,WNK1,PPP1R3F" Gene Family 1293 Minor histocompatibility antigens|FERM domain containing genenames.org 6.88E-09 4.15E-06 5.19E-07 3.62E-06 23 50 "PLEKHH1,EPB41L5,KRIT1,FRMPD4,EPB41,EPB41L1,EPB41L2,PTK2B,FERMT2,FRMD5,FRMD3,JAK1,JAK2,MYO7A,EPB41L4B,PTK2,PTPN13,RDX,FRMPD1,FERMT1,EPB41L3,PLEKHH2,FRMD6" Gene Family 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 8.46E-09 5.11E-06 5.68E-07 3.97E-06 54 193 "DSCAML1,ADGRF5,ALCAM,SEMA7A,SEMA4G,IGDCC4,CADM3,CD86,MYOM2,IGLON5,CNTFR,CNTN1,NECTIN3,CSF1R,BOC,DCC,CDON,DSCAM,FCGR1A,FCGR1B,FCGR3A,SEMA4D,FLT1,NPTN,CHL1,IGSF5,MALT1,KIRREL3,PTPRT,IL1RAPL1,IGSF21,VSIG4,IGSF1,IL6R,IL11RA,KIT,CD200,MDGA1,NRCAM,CNTN3,SDK2,MDGA2,KIRREL1,IGSF9B,ROBO3,CNTN2,OBSL1,TEK,TIE1,ICAM5,HEPACAM,CADM1,SEMA3B,ADAMTSL3" Gene Family 925 Granins genenames.org 7.54E-08 4.55E-05 4.55E-06 3.18E-05 8 8 "CHGA,CHGB,PCSK1N,GNAS,SCG3,SCG5,VGF,SCG2" Gene Family 28 Zinc fingers C2H2-type|BTB domain containing genenames.org 8.47E-08 5.11E-05 4.65E-06 3.25E-05 140 720 "ZNF608,ZNF578,ZFAT,ZSCAN18,ZBTB10,ZNF582,ZNF583,ZNF599,SCAPER,JAZF1,ZNF555,ZNF501,ZNF445,ZNF521,ZFP28,HINFP,ZSCAN23,ZNF337,ZEB2,ZBTB24,EGR3,ZNF391,ZNF549,ZNF461,ZNF585B,ZIC4,ZSCAN30,ZNF589,ZNF605,ZNF512,ZNF44,SALL3,ZNF234,ZNF274,ZNF559,ZNF276,GLI2,INSM2,ZNF782,PRDM5,ZNF496,ZBTB49,ZBTB45,ZHX1,KLF12,ZNF491,ZNF181,ZNF546,ZIC5,SCRT2,ZNF678,ZNF680,ZNF92,ZNF862,CHAMP1,ZNF713,ZNF827,ZNF655,ZNF426,ZSCAN32,ZIK1,ZSCAN2,ZNF615,ZNF844,ZNF793,ZNF493,FEZF2,HKR1,ZNF532,ZNF671,ZNF354C,ZNF568,ZNF331,SALL1,ZFP2,ZNF821,ZFP30,ZNF365,ZNF430,ZNF334,ZKSCAN3,ZFP1,ZNF667,ZNF415,ZHX3,SP2,SP4,ZNF423,ZBTB43,ZNF621,ZNF302,ZSCAN29,ATMIN,ZFP90,ZEB1,ZFPM2,ZNF34,ZNF106,GZF1,ZFP91,ZNF384,TRPS1,ZKSCAN5,ZNF610,ZNF709,ZNF781,ZFP37,ZBTB14,ZIC1,ZIC2,ZIC3,ZNF711,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,ZNF45,ZFP41,ZNF540,ZNF70,ZNF74,ZNF138,ZNF142,ZBTB38,ZBTB16,ZNF154,ZNF177,ZNF184,ZSCAN26,ZNF189,ZNF195,ZNF213,ZNF225,ZXDA,PRDM10,ZNF248,ZNF30" Gene Family 253 Calcium voltage-gated channel subunits genenames.org 5.58E-07 3.37E-04 2.81E-05 1.96E-04 14 26 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG3,CACNG2" Gene Family 775 Myb/SANT domain containing|Trinucleotide repeat containing genenames.org 2.41E-06 1.46E-03 1.12E-04 7.81E-04 13 25 "EP400,TNRC6C,CASK,MAGI1,NUMBL,NCOR2,MED12,TOX3,TNRC6A,CELF3,ATXN2,ZNF384,JPH3" Gene Family 904 Calcium voltage-gated channel subunits|Membrane associated guanylate kinases genenames.org 4.26E-06 2.57E-03 1.84E-04 1.28E-03 13 26 "CASK,CACNB2,CACNB4,MAGI1,TJP2,MAGI2,DLG2,DLG3,DLG4,MPP6,MPP2,MAGI3,TJP1" Gene Family 765 Synaptotagmins genenames.org 8.53E-06 5.15E-03 3.44E-04 2.40E-03 10 17 "SYT13,SYT6,SYT15,SYT3,SYT17,SYT9,SYT11,SYT1,SYT4,SYT5" Gene Family 274 Potassium voltage-gated channels genenames.org 1.27E-05 7.66E-03 4.79E-04 3.34E-03 16 40 "KCNH8,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNQ2,KCNQ3" Gene Family 858 Potassium voltage-gated channel regulatory subunits|EF-hand domain containing genenames.org 1.98E-05 1.20E-02 6.67E-04 4.66E-03 9 15 "DPP10,KCNAB2,KCNAB3,DPP6,KCNIP3,KCNIP2,KCNIP1,KCNE5,KCNAB1" Gene Family 21 Non-clustered protocadherins genenames.org 1.99E-05 1.20E-02 6.67E-04 4.66E-03 8 12 "PCDH19,PCDH10,PCDH17,PCDH11X,PCDH8,PCDH9,PCDH18,PCDH20" Gene Family 1147 PHD finger proteins|Lysine methyltransferases|PWWP domain containing genenames.org 2.38E-05 1.44E-02 7.56E-04 5.28E-03 11 22 "PWWP2A,BRPF3,ZMYND11,GLYR1,PSIP1,MUM1,ZCWPW1,MBD5,NSD1,ZMYND8,NSD2" Gene Family 757 SRY-boxes genenames.org 3.19E-05 1.92E-02 9.08E-04 6.34E-03 10 19 "SOX21,SOX8,SOX6,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15" Gene Family 752 Solute carriers genenames.org 3.55E-05 2.15E-02 9.08E-04 6.34E-03 78 395 "SLC25A25,SLC12A5,SLC24A4,SLC44A5,SLC7A14,SLC4A4,SLC2A11,SLC25A14,SLC5A11,SLC16A4,SLC22A6,SLC24A2,SLC25A27,SLC4A7,SLC4A8,SLC35F1,SLC32A1,SLC45A1,SLC29A4,SLC12A6,SLC25A18,SLC43A2,SLC9B2,SLC37A3,SLC2A6,SLC6A17,SLC35G1,SLCO1C1,SLC11A2,SLC10A4,SLC25A23,SLC36A4,SLC26A11,SLC22A23,SLC25A48,SLC25A41,SLC6A15,SLC25A36,SLC30A10,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,SLC6A1,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,SLC37A2,SLC19A3,SLC35G2,SLC44A1,SLC35A4,MTCH1,SLC13A3,SLC47A2,SLC26A10,SLC30A3,SLC30A4,SLC38A1,SLC17A7,SLC17A6,SLC39A12,SLC4A10" Gene Family 409 Armadillo repeat containing genenames.org 3.69E-05 2.23E-02 9.08E-04 6.34E-03 16 43 "GPRASP2,ARMC12,PKP4,APC,ARMC8,CTNND1,CTNND2,GPRASP1,ARMCX4,ARMCX2,APC2,ARMCX1,KPNA5,RAP1GDS1,ARMC5,BHLHB9" Gene Family 1052 I-set domain containing|IgLON cell adhesion molecules genenames.org 3.76E-05 2.27E-02 9.08E-04 6.34E-03 5 5 "IGLON5,NTM,NEGR1,LSAMP,OPCML" Gene Family 1127 Phospholipid phosphatase related genenames.org 3.76E-05 2.27E-02 9.08E-04 6.34E-03 5 5 "PLPPR4,PLPPR1,PLPPR3,PLPPR2,PLPPR5" Gene Family 1199 Glutamate ionotropic receptor kainate type subunits genenames.org 3.76E-05 2.27E-02 9.08E-04 6.34E-03 5 5 "GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Gene Family 863 EF-hand domain containing genenames.org 4.14E-05 2.50E-02 9.61E-04 6.71E-03 49 219 "SLC25A25,DST,CACNA1B,CACNA1E,CALB1,CALB2,CABP7,CALM1,CAPN3,REPS2,EPS15L1,MYL6B,CABP1,PLCH2,DGKB,DGKG,AIF1L,CALN1,RASGRP1,RASGRP2,NCALD,HPCAL4,EFCAB2,CGREF1,GPD2,PLCD4,HPCA,NKD1,EFHB,MYL3,NUCB1,NUCB2,PLCD1,SLC25A23,NECAB2,KCNIP3,KCNIP2,KCNIP1,RYR3,S100B,ITSN1,EFHD1,SPTAN1,NECAB1,RHBDL3,DNAH7,VSNL1,MICU3,FSTL5" Gene Family 736 Immunoglobulin like domain containing|Semaphorins genenames.org 5.65E-05 3.41E-02 1.20E-03 8.41E-03 10 20 "SEMA6A,SEMA7A,SEMA4G,SEMA3D,SEMA6C,SEMA4D,SEMA5B,SEMA6D,SEMA4A,SEMA3B" Gene Family 438 Sialyltransferases genenames.org 5.65E-05 3.41E-02 1.20E-03 8.41E-03 10 20 "ST3GAL5,ST8SIA3,ST3GAL6,ST6GALNAC3,ST8SIA5,ST6GALNAC6,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" Gene Family 321 Receptor Tyrosine Kinases|Protein phosphatase 1 regulatory subunits genenames.org 5.78E-05 3.49E-02 1.20E-03 8.41E-03 15 40 "ALK,DDR1,AATK,CSF1R,FGFR1,FGFR3,FLT1,KIT,NTRK2,NTRK3,DDR2,PDGFRA,RET,TEK,TIE1" Gene Family 760 Fibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors genenames.org 6.15E-05 3.72E-02 1.24E-03 8.65E-03 25 88 "CASKIN1,PPFIA4,PPFIA2,PPFIA1,DGKD,PPFIA3,SFMBT2,L3MBTL4,SHANK1,PHC2,EPHA5,EPHB1,SCML2,SAMD5,SAMD14,SAMD9,EPHA10,PPP1R9A,CNKSR2,SHANK2,SCMH1,SAMSN1,KAZN,DDHD2,ANKS1B" Gene Family 721 Rho GTPase activating proteins genenames.org 8.04E-05 4.85E-02 1.57E-03 1.09E-02 17 50 "ARHGAP20,ARHGAP5,ARHGAP33,CHN1,CHN2,ARHGAP22,ARHGAP32,ARHGAP24,SRGAP3,FAM13A,DLC1,ARHGAP19,ARHGAP36,ARHGAP12,OPHN1,ARHGAP26,ARHGAP9" Gene Family 281 Glutamate metabotropic receptors genenames.org 9.04E-05 5.46E-02 1.65E-03 1.15E-02 6 8 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Gene Family 622 Kinesins|Protein phosphatase 1 regulatory subunits genenames.org 9.50E-05 5.74E-02 1.65E-03 1.15E-02 16 46 "KIF6,KIF1A,KIF26A,KIF19,KIF3A,KIF2A,KIF5A,KIF5C,KIFC3,KIF7,KIF27,KIF21A,KIF16B,KIF13A,KIF21B,KIF1B" Gene Family 813 "Fibronectin type III domain containing|Protein tyrosine phosphatases, receptor type" genenames.org 9.56E-05 5.78E-02 1.65E-03 1.15E-02 10 21 "PTPRT,PTPRB,PTPRD,PTPRE,PTPRG,PTPRH,PTPRN,PTPRN2,PTPRO,PTPRZ1" Gene Family 720 Regulators of G-protein signaling genenames.org 9.56E-05 5.78E-02 1.65E-03 1.15E-02 10 21 "RGS20,RGS11,RGS9,RGS6,RGS17,RGS3,RGS4,RGS7,RGS10,RGS12" Gene Family 778 Tubulins genenames.org 1.61E-04 9.69E-02 2.69E-03 1.88E-02 11 26 "TUBD1,TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBA3FP,TUBB2A,TUBB1,TUBA1A" Gene Family 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 1.82E-04 1.10E-01 2.97E-03 2.07E-02 17 53 "MTA3,EP400,MIER1,NCOR1,NCOR2,ELMSAN1,DMTF1,EZH1,MSANTD4,MIER3,RCOR2,GON4L,MSANTD2,SMARCC2,RCOR3,TRERF1,BDP1" Gene Family 563 Gamma-aminobutyric acid type A receptor subunits genenames.org 2.27E-04 1.37E-01 3.61E-03 2.52E-02 9 19 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2" Gene Family 861 Kelch like|BTB domain containing genenames.org 2.46E-04 1.49E-01 3.81E-03 2.66E-02 32 134 "KLHL32,KLHL13,SPOP,ZBTB10,BACH1,RCBTB2,ZBTB24,KLHL3,RHOBTB1,KBTBD11,KLHL5,ANKFY1,KBTBD12,ZBTB49,ZBTB45,BACH2,BTBD17,KLHL23,KLHL11,BTBD3,KBTBD4,BTBD7,ABTB1,ZBTB43,KLHL7,KLHL4,GZF1,NACC2,ZBTB14,ZBTB38,ZBTB16,GAN" Gene Family 833 Regulating synaptic membrane exocytosis family|PDZ domain containing genenames.org 2.98E-04 1.80E-01 4.28E-03 2.99E-02 4 4 "RIMS4,RIMS2,RIMS3,RIMS1" Gene Family 777 Tropomyosins genenames.org 2.98E-04 1.80E-01 4.28E-03 2.99E-02 4 4 "TPM1,TPM2,TPM3,TPM4" Gene Family 951 Erythrocyte membrane protein band 4.1|FERM domain containing genenames.org 2.98E-04 1.80E-01 4.28E-03 2.99E-02 4 4 "EPB41,EPB41L1,EPB41L2,EPB41L3" Gene Family 681 Phosphodiesterases genenames.org 3.71E-04 2.24E-01 5.21E-03 3.64E-02 10 24 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Gene Family 366 Ubiquitin specific peptidases genenames.org 3.80E-04 2.30E-01 5.22E-03 3.64E-02 17 56 "USP31,USP35,USP28,USP37,USP6,USP2,USP3,USPL1,USP16,USP21,USP19,USP51,USP54,USP47,USP33,USP22,USP1" Gene Family 651 Mitogen-activated protein kinases genenames.org 4.37E-04 2.64E-01 5.87E-03 4.10E-02 7 13 "MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12" Gene Family 1179 Apolipoproteins|Sushi domain containing genenames.org 4.79E-04 2.89E-01 6.28E-03 4.39E-02 17 57 "CSMD2,CSMD3,SRPX,SUSD5,VCAN,NCAN,SEZ6L2,SEZ6,GABBR1,HP,HPR,MASP1,SUSD4,SELL,BCAN,CSMD1,SEZ6L" Gene Family 262 "G protein-coupled receptors, Class A orphans" genenames.org 5.16E-04 3.12E-01 6.64E-03 4.63E-02 21 78 "LGR5,GPR146,GPR37L1,GPR61,GPR153,GPR162,GPR75,GPR12,GPR17,GPR19,GPR22,GPR26,GPR34,GPR37,GPR45,GPR62,GPR88,GPR173,GPR85,LGR4,GPR161" Gene Family 24 Cadherin related genenames.org 5.42E-04 3.28E-01 6.83E-03 4.77E-02 8 17 "CDHR1,FAT3,DCHS2,FAT4,RET,CLSTN1,CLSTN2,PCDH15" Gene Family 87 Zinc fingers MYND-type genenames.org 5.70E-04 3.45E-01 7.03E-03 4.91E-02 9 21 "RUNX1T1,CBFA2T2,ANKMY1,ZMYND10,ZMYND15,ZMYND11,USP19,PDCD2,ZMYND8" Gene Family 362 Ring finger proteins|WD repeat domain containing genenames.org 5.88E-04 3.55E-01 7.11E-03 4.96E-02 52 262 "WDR35,APAF1,DCAF5,BTRC,LRBA,LRWD1,COPB2,PLAA,SEC31B,DCAF4,DCAF8,WDR20,DYNC1I1,EML1,CORO2B,RACK1,WDR83,NBEA,EML4,STXBP5,POC1B,WDR49,NLE1,STRN3,PPP2R2B,PPP2R2C,BCAS3,WDR25,EML5,ATG16L1,NWD1,ELP2,FBXW7,KIF21A,AMBRA1,SEC31A,PAAF1,WDR37,WDR47,IFT122,MAPKBP1,WDTC1,KIF21B,MLST8,FBXW11,TBL1X,DMXL2,WDR7,HIRA,CFAP52,EML6,AAAS" Gene Family 88 Zinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases genenames.org 6.42E-04 3.88E-01 7.60E-03 5.31E-02 23 90 "DPF1,KDM5D,PHF12,KMT2C,CHD5,PHF14,PYGO1,PHF19,PHF20L1,ING4,BRPF3,ZMYND11,KDM2B,DIDO1,ING3,DPF2,PHF24,NSD1,KAT6B,ZMYND8,NSD2,KAT6A,DPF3" Gene Family 396 A-kinase anchoring proteins genenames.org 7.01E-04 4.23E-01 8.14E-03 5.68E-02 11 30 "WASF1,AKAP7,AKAP6,AKAP5,MYRIP,AKAP12,AKAP3,NBEA,MAP2,MYO7A,SPHKAP" Gene Family 403 Ankyrin repeat domain containing|BRCA1 B complex genenames.org 9.48E-04 5.73E-01 1.08E-02 7.54E-02 48 242 "KIDINS220,CASKIN1,HACE1,OSBPL1A,PLA2G6,ANK1,ANK2,ANK3,BARD1,KRIT1,DGKI,HECTD1,ANKRD35,ANKRD44,CLIP3,SNCAIP,PPP1R16B,DAPK1,GIT2,SHANK1,ANKRD46,FEM1B,ASB3,ANKRD13B,ANKMY1,AGAP2,AGAP3,ANKFY1,GLS,SOWAHA,GIT1,ANKRD16,ANKHD1,RNASEL,ASAP3,ANKRD6,SHANK2,ABTB1,ANKRD36,ANKFN1,MYO16,KANK1,ANKRD28,ANKRD12,ANKRD24,TP53BP2,ANKRD20A2,ANKS1B" Gene Family 420 Basic helix-loop-helix proteins genenames.org 1.06E-03 6.38E-01 1.18E-02 8.25E-02 26 110 "ARNTL,ASCL1,NCOA1,CLOCK,ARNT2,OLIG1,HEYL,OLIG2,ATOH8,HES5,MITF,MXI1,MYCN,NEUROD1,NEUROD2,NHLH1,HES6,NPAS3,MESP1,TAL1,TCF4,TCF12,HIF3A,HEY1,BHLHB9,HEY2" Gene Family 290 Acid sensing ion channel subunits genenames.org 1.15E-03 6.95E-01 1.26E-02 8.82E-02 4 5 "ASIC2,ASIC1,ASIC3,ASIC4" Gene Family 725 RNA binding motif containing genenames.org 1.18E-03 7.13E-01 1.27E-02 8.88E-02 43 213 "RBM10,PTBP2,SRSF11,RBM39,PABPC5,MYEF2,ALKBH8,G3BP2,CPEB2,RBM12,ELAVL2,ELAVL3,ELAVL4,SYNCRIP,CELF1,PPARGC1A,RNPS1,ZNF638,HTATSF1,CELF3,CELF5,SRSF12,MSI1,PABPC1L2A,HNRNPM,CNOT4,ENOX1,RAVER2,SAFB,SFPQ,TRA2B,PUF60,SCAF8,CPEB3,CPEB4,RBM34,RBM26,RALYL,RBFOX2,RBFOX3,CELF4,NELFE,HNRNPA3" Gene Family 903 Myotubularins|Phosphoinositide phosphatases genenames.org 1.30E-03 7.86E-01 1.38E-02 9.63E-02 7 15 "MTMR9,MTMR3,MTMR2,MTMR7,MTMR10,SBF1,MTMR14" Gene Family 763 "Sulfotransferases, membrane bound" genenames.org 1.42E-03 8.57E-01 1.48E-02 1.03E-01 12 37 "NDST3,GAL3ST1,HS3ST5,HS3ST4,HS3ST2,CHST15,CHST6,HS6ST3,GAL3ST4,CHST8,CHST5,GAL3ST3" Gene Family 741 SH2 domain containing genenames.org 1.49E-03 9.02E-01 1.53E-02 1.07E-01 24 101 "BCAR3,BTK,SOCS6,CHN1,CHN2,SH2B1,SOCS5,FER,FGR,FYN,GRB10,JAK2,MATK,SHC3,PIK3R1,SH3BP2,SHC4,SLA,TNS2,TNS1,VAV1,VAV2,SHD,SOCS4" Gene Family 1289 N-BAR domain containing genenames.org 1.90E-03 1.00E+00 1.91E-02 1.33E-01 6 12 "AMPH,BIN1,SH3GLB1,SH3GL2,SH3GL3,SH3GLB2" Gene Family 276 Potassium voltage-gated channel subfamily J genenames.org 2.06E-03 1.00E+00 2.01E-02 1.40E-01 7 16 "KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16" Gene Family 672 Parkinson disease associated genes|Ubiquitin C-terminal hydrolases genenames.org 2.06E-03 1.00E+00 2.01E-02 1.40E-01 7 16 "PLA2G6,FBXO7,EIF4G1,LRRK2,SNCA,ATP13A2,UCHL1" Gene Family 1261 Zinc fingers C2H2C-type genenames.org 2.36E-03 1.00E+00 2.16E-02 1.51E-01 3 3 "ST18,MYT1,MYT1L" Gene Family 1325 Synapsins genenames.org 2.36E-03 1.00E+00 2.16E-02 1.51E-01 3 3 "SYN3,SYN1,SYN2" Gene Family 912 "Adhesion G protein-coupled receptors, subfamily B" genenames.org 2.36E-03 1.00E+00 2.16E-02 1.51E-01 3 3 "ADGRB1,ADGRB2,ADGRB3" Gene Family 774 Transmembrane and coiled-coil domain containing genenames.org 2.36E-03 1.00E+00 2.16E-02 1.51E-01 3 3 "TMCC3,TMCC2,TMCC1" Gene Family 829 Copines genenames.org 2.61E-03 1.00E+00 2.31E-02 1.62E-01 5 9 "CPNE2,CPNE5,CPNE6,CPNE9,CPNE4" Gene Family 1209 ATPases Ca2+ transporting genenames.org 2.61E-03 1.00E+00 2.31E-02 1.62E-01 5 9 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP2C1" Gene Family 1151 Phosphatidylinositol transfer proteins genenames.org 3.09E-03 1.00E+00 2.67E-02 1.86E-01 4 6 "PITPNM2,PITPNM3,PITPNC1,PITPNB" Gene Family 255 Potassium calcium-activated channels genenames.org 3.09E-03 1.00E+00 2.67E-02 1.86E-01 4 6 "KCNMA1,KCNN1,KCNN2,KCNN3" Gene Family 81 Zinc fingers FYVE-type genenames.org 3.65E-03 1.00E+00 3.11E-02 2.17E-01 10 31 "FGD2,ZFYVE28,MTMR3,ZFYVE9,ZFYVE16,ANKFY1,ZFYVE27,ZFYVE21,RUFY2,FGD4" Gene Family 590 Receptor Tyrosine Kinases|CD molecules|V-set domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 3.94E-03 1.00E+00 3.31E-02 2.31E-01 33 163 "ADORA3,ALCAM,CADM3,VSTM2A,CD86,JAM2,IGLON5,NECTIN3,HAPLN1,VCAN,NCAN,SIRPA,SEMA3D,IGSF6,SIRPB1,SIGLEC8,BTN2A1,IGSF21,VSIG4,HAPLN2,MOG,TREM2,PILRA,VSTM2L,SCN2B,SCN4B,BCAN,IGSF9B,SCN3B,HEPACAM,CADM1,CADM2,SIGLEC10" Gene Family 1178 EF-hand domain containing|Diacylglycerol kinases genenames.org 4.67E-03 1.00E+00 3.85E-02 2.69E-01 5 10 "DGKZ,DGKD,DGKI,DGKB,DGKG" Gene Family 1079 Atypical dual specificity phosphatases|Phosphoinositide phosphatases genenames.org 4.72E-03 1.00E+00 3.85E-02 2.69E-01 10 32 "SYNJ1,SYNJ2,MTMR3,MTMR2,MTMR7,INPP5K,INPP1,INPP5B,OCRL,MTMR14" Gene Family 1288 F-BAR domain containing genenames.org 5.44E-03 1.00E+00 4.38E-02 3.06E-01 8 23 "GAS7,SRGAP3,FER,PACSIN2,PACSIN1,FNBP1,FCHO1,SRGAP2B" Gene Family 395 ArfGAPs genenames.org 6.01E-03 1.00E+00 4.78E-02 3.34E-01 10 33 "GIT2,AGAP2,AGAP3,ARFGAP2,ADAP1,AGFG1,SMAP1,GIT1,ASAP3,ARFGAP1" Gene Family 1208 ATPase Na+/K+ transporting subunits genenames.org 6.49E-03 1.00E+00 4.93E-02 3.44E-01 4 7 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Gene Family 1201 Glutamate ionotropic receptor NMDA type subunits genenames.org 6.49E-03 1.00E+00 4.93E-02 3.44E-01 4 7 "GRIN3A,GRIN1,GRIN2C,GRIN2D" Gene Family 1098 Myosin heavy chains genenames.org 7.34E-03 1.00E+00 4.93E-02 3.44E-01 6 15 "MYH7B,MYH3,MYH6,MYH7,MYH14,MYH15" Gene Family 696 Protein phosphatase 2 regulatory subunits genenames.org 7.34E-03 1.00E+00 4.93E-02 3.44E-01 6 15 "STRN3,PPP2R2B,PPP2R2C,PPP2R5C,PPP2R5E,PPP2R3C" Gene Family 688 Proline rich transmembrane proteins genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "PRRT2,PRRT1,PRRT4" Gene Family 574 Hyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "VCAN,NCAN,BCAN" Gene Family 820 "Guanylate cyclases, soluble" genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "GUCY1A2,GUCY1A1,GUCY1B1" Gene Family 211 Adenosine receptors genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "ADORA1,ADORA2A,ADORA3" Gene Family 1204 V-set domain containing|Immunoglobulin like domain containing|Sodium voltage-gated channel beta subunits genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "SCN2B,SCN4B,SCN3B" Gene Family 1138 Stathmins genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "STMN2,STMN1,STMN4" Gene Family 1096 Erb-b2 receptor tyrosine kinases genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "EGFR,ERBB2,ERBB4" Gene Family 659 Na+/K+ transporting ATPase interacting genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "NKAIN4,NKAIN1,NKAIN2" Gene Family 1200 Glutamate ionotropic receptor AMPA type subunits genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "GRIA1,GRIA2,GRIA4" Gene Family 1077 "6-phosphofructo-2-kinases/fructose-2,6-biphosphatases" genenames.org 7.35E-03 1.00E+00 4.93E-02 3.44E-01 3 4 "PFKFB2,PFKFB3,PFKFB4" Coexpression 18223198-TableS3 Human Brain_Chen-Plotkin08_747genes GeneSigDB 1.65E-100 1.90E-96 1.90E-96 1.89E-95 312 594 "SYN3,ACTN2,ADD2,SLC12A5,ADORA3,NLGN4X,KIAA1324,DOC2A,AMPH,PPFIA4,PKP4,CNTNAP1,APBA2,KCNAB2,GAS7,DGKZ,AQP4,TMEFF1,ARHGDIG,ASCL1,BRINP2,ATP1A2,ATP2A2,ATP2B1,ATP2B3,NOL4,ATP6V0A1,ADAM23,ADGRB2,CFLAR,CDK5R1,SYNJ1,CACNA1G,BSN,RAB29,WASF1,DDR1,CACNB4,KALRN,CAMK2A,CAMK2B,HIP1R,LDB2,INA,CDC42,DCLK1,CDH18,LARGE1,DLGAP2,DLGAP1,CHGA,CHGB,CHN1,B4GALT6,NRXN3,NRXN1,TMEM59L,TJP2,QKI,SULT4A1,LY86,FHL5,CNR1,CABP1,PREPL,CRYM,MICAL2,IPCEF1,SIPA1L1,VCAN,PDE4DIP,CNTNAP2,DZIP3,CALY,ERC2,GPRASP1,ARHGAP32,FRMPD4,KIAA0513,PHYHIP,DCTN1,SNAP91,SV2B,SV2A,SRGAP3,AK5,DLG2,DLG3,DLG4,DYNC1I1,DOCK2,DPP6,DTNA,ECM2,USH1C,SEZ6L2,EEF1A2,RASGRP1,EFNB3,EGFR,EGR3,AASS,ELAVL4,RGS17,SRPK3,BSCL2,EMX2,ENO2,DMTN,EPS8,NCALD,RTN3,RASL12,NRN1,ABCA8,CACNG3,PTK2B,TUBB3,TUBB4A,FCGRT,OLFM1,FGF13,ACTL6B,BAIAP2,FGR,HPCAL4,CAP2,RASL10A,CAMKK2,PNMA2,GABRA1,CHL1,GABRB3,GAD1,GAD2,ARPP21,GAP43,HIGD1B,ATP8A2,GATM,GFRA2,RUNDC3A,GLS,PCSK1N,GNAO1,GNAS,GNG3,GPR22,PCLO,STMN2,GRIA1,GRIN1,GRM5,GRM7,CIT,PTPRT,GSN,ACOT7,HMGCR,HNMT,HPCA,HTR2A,IFI16,SHISAL1,TUBB2B,ITPKA,ITPKB,KCNB1,KCND3,KCNJ4,KCNK1,KCNQ2,KLC1,KTN1,L1CAM,LAMP2,MAP2,MATN2,MEF2C,MEST,SCAMP5,CD200,TAGLN3,FXYD7,NAP1L2,FXYD6,NAP1L3,NELL1,NELL2,NPTX1,NRGN,OPA1,OPCML,PAK3,PCSK2,PDE4A,CDK14,GDAP1L1,SERPINI1,CAMKV,SNX10,PLXNB1,TRHDE,FSD1,PPP3CA,PPP3CB,PRKAR1B,PRKCB,PRKCZ,DIRAS2,LRRC49,SIDT1,PTPN13,PTPRB,PTPRN,PTPRO,IQSEC3,RAP1GAP,SUSD4,RDX,ZMAT4,RGS4,RGS7,RNASE1,NUDT11,ZFHX4,PNMA8A,FBXW7,RTN1,CSRNP3,SCN2A,IL17RB,SELL,SCG5,ITSN1,SH3GL2,CNKSR2,CLSTN1,ZNF365,RPH3A,WDR47,PKNOX2,SLC8A2,ARHGEF40,SHANK2,EFHD1,SLCO1A2,OGDHL,RIMS1,SNAP25,SNCB,SNCA,FAIM2,SCN3B,MYT1L,NMNAT2,BEX1,ITPRID2,ERBIN,NCDN,ELOVL4,STX1A,KANK1,ARHGEF9,PLCB1,SYN1,SYN2,SYP,SYT1,SYT5,TAC1,KIAA1107,TBL1X,SATB2,CUX2,TCF12,WDR7,PHF24,TMEM151B,RALYL,PSD3,TNS2,TGFBR3,TJP1,ICAM5,RIMBP2,R3HDM1,PARD3,TNS1,SEZ6L,RUNDC3B,TUBB2A,UCHL1,VSNL1,WIPF1,KLC2,ZIC1,NDRG4,REEP1,ZNF184,SYNC,SLC30A3,PRDM2,STMN4,SCG2,SLC17A7,KCNAB1,CAMK1G,ACTR3B,SSPN,NETO2,AP3B2" Coexpression 19621087-Table1d Mouse EmbryonicStemCell_Abranches09_1170genes GeneSigDB 4.34E-67 5.02E-63 2.51E-63 2.50E-62 283 651 "ABAT,GALNT16,ADCY6,RNF157,SORCS1,PCDH19,OSBPL6,TXNDC16,ALCAM,ABCD2,ANK2,APBA2,APP,CASK,CADPS,ASCL1,ASTN1,TMEM108,DPY19L3,ADGRB2,MPDZ,DCAF5,AP1M1,SGCE,CACNA1G,PTBP2,BRSK2,SPAG9,CBLN1,LONRF2,CDH2,DCLK1,MAGI1,CACNA2D2,RCBTB2,SOCS6,SLIT2,LHX2,FBXO7,HOMER3,COL4A5,LETMD1,NECTIN3,SLC35F1,FAM171B,ANKRD44,CLIP3,SNCAIP,LRIG1,FEZ1,ATRNL1,SIPA1L1,NCAN,CNTNAP2,SLITRK5,DZIP3,PHF14,CTNND2,GPSM1,BOC,DOCK4,HDAC9,TCAF1,TOX,RASSF2,SCRN1,CTIF,DBN1,DCC,JAKMIP2,RHOBTB1,SRGAP3,TMCC2,ARNT2,USP3,CDON,DPYSL2,EDNRB,PHC2,EFNA2,YAF2,EFNB3,PHF20L1,PLXNC1,ELAVL4,EN2,PLEKHO1,GPHN,STX2,RTN3,EXTL2,KATNAL1,ADGRV1,EYA1,WAC,FABP7,TBC1D16,TMEM132C,OLFM1,SPSB4,FGF13,MEX3B,FOXG1,EVL,DPYSL4,NBEA,DACH2,FYN,MEGF10,ILDR2,ZMYND11,GAP43,GLRB,TOX3,GNAS,ADGRA3,GP1BB,GPM6A,GPM6B,GRIK5,RNF165,MFSD2A,SOX21,ADAMTS6,TOX2,ZHX1,BACH2,NEGR1,MSL1,NKD1,DOCK7,HES5,LIX1,LRRTM1,KCNA1,KIF5C,LRRC4B,CAMK2N2,FGFBP3,LSAMP,SMAD1,NAT8L,MAN2A2,MARK1,MEIS1,MEIS2,PPM1L,MKLN1,MMP16,MN1,MSI1,RSPO2,SAMD14,MYO5A,NCAM1,NELL2,NOVA1,NRCAM,OPHN1,CNTN3,PAX6,PCDH8,GPR173,TMOD2,SEMA5B,PCDH18,PURG,LRP12,PRRX1,FAT3,POU3F4,IRX1,PPP2R5E,PKIA,MAPK10,PROX1,GDPD1,RELN,SLC22A23,LRRC49,LAMA1,PTH1R,PTPRD,PTPRN2,PTPRZ1,NKAIN1,USP47,FAT4,FEZF2,GAL3ST4,RFX3,RFX4,ZFHX4,CCDC82,ROBO2,ATAT1,WLS,RTKN,CLIP1,RTN1,RXRA,AMER2,SEMA6D,SATB1,CSRNP3,SCN8A,TNFRSF19,SOX6,GALNT10,RASA3,HSPA4L,SCG5,ITSN1,PPM1E,ARX,FHOD3,CNKSR2,DZIP1,SLC1A2,CXXC4,SMARCE1,IFT122,MBD5,TMCC1,SOX11,SP4,KIF1B,NPAS3,NFASC,CLSTN2,ERBIN,MPRIP,ELOVL4,SEPT3,SYNE2,SYT1,PJA1,ADGRL3,EHBP1,TCF4,SATB2,ZEB1,TCF12,PCDHGA11,PCDHA1,GPR161,FBXL16,ENHO,ASXL3,NR2E1,TRIO,STXBP4,SSBP2,TTC3,CADM1,RPRM,UBE2H,FLRT2,FAM181B,BCL2L13,MTCH1,VLDLR,NSD2,ZIC1,ZFP41,ATP6V0E2,FMN2,REEP1,DPYSL5,ZXDA,LRP8,SHD,STOX2,TMEM163,WNK2,MVB12B,FZD3,ST7,VANGL2,ADAMTS10,NHSL1,ST8SIA2,SENP7" Coexpression 19621087-Table1e Mouse EmbryonicStemCell_Abranches09_919genes GeneSigDB 1.18E-65 1.37E-61 4.57E-62 4.54E-61 254 555 "TTYH1,ASIC1,ACHE,NCKAP5,CSMD2,GPRIN1,ADCY5,ADCY8,ADD2,SLC12A5,RNF150,KIDINS220,SNX32,ARHGAP20,PCDH10,LCORL,CNIH2,APC,SEMA4G,ASCL1,RNF182,ATP6V1G2,BCL7A,DCAF5,CDK5R1,SYNJ1,ARHGEF7,NIPA1,CACNB4,CALM1,KALRN,HAP1,RUNX1T1,CDC25B,CDC42,DCLK1,ARHGAP33,EVI5L,MAGI1,CDO1,CFL2,ADGRG1,CHGB,CHN2,CHRNA4,RAB3C,CHRNB2,JAM2,SLIT2,NRXN3,NRXN1,IGLON5,CNTN1,AKAP6,SLC25A27,CNTNAP2,SDC3,ERC2,CTNND2,ST18,GPRASP1,HP1BP3,SRGAP3,NTM,DLG4,DNM1,OLIG1,CD99L2,EDIL3,EDNRB,EFNA2,KMT5B,ELAVL3,ELAVL4,OLIG2,LRRC23,EPHA5,APC2,NRN1,CLVS1,ZIC4,ACTL6B,IP6K2,PSD2,SGIP1,ST6GALNAC3,DLL3,STAU2,TPPP3,ZMAT1,GABBR1,CHL1,TMEM8B,SRRM4,DNER,CYP46A1,GFRA1,GLS,PCDH11X,OS9,RAB40B,GP1BB,GPM6B,GPR22,GRIA2,PARD3B,GRIK1,GRIK2,KIF3A,IGSF21,KLF12,GABARAPL2,IGFBPL1,SCRT2,INSM1,TUBB2B,KCNC1,KCND2,KCND3,KCNK2,KCNN1,KCNQ2,KIF5A,KIF5C,L1CAM,LMO2,LSS,MAPT,MARK1,MBD1,CD200,TAGLN3,MXI1,RTL5,MYT1,NFIA,NFIX,NHLH1,NPR2,NTRK2,GPR137C,PBX1,PCDH9,GNG2,SERPINI1,NALCN,GPSM2,SMOX,PRRX1,SLC36A4,POU3F2,POU3F4,DRAM2,POU6F1,MINDY2,PCDHB17P,LRRN3,NKAIN4,RASGEF1B,MAPK10,VPS13C,CNTLN,PTPRO,TUG1,RBBP6,KHDRBS2,RGS7,TTLL7,RNASEL,MEG3,ATAT1,SCN3A,HES6,SMPD3,MRAS,ZFP30,ITSN1,DOCK10,NTNG1,SYBU,ST8SIA1,DZIP1,WDR47,YPEL4,SIRT2,CCDC88A,NAPB,SCMH1,ZKSCAN3,SMARCD3,LIMCH1,SNAP25,MYO16,KDM4B,SCN3B,MYT1L,TNIK,SOX5,KIF21B,GLT8D1,CDK19,NPAS3,SRPK2,SST,NACAD,MAPK8IP3,TTBK2,STXBP1,FAM168A,KLHL7,MLC1,ARHGEF9,SYT4,ROBO3,CAMTA1,CNTN2,ADGRL3,ACSL6,TCF4,CUX2,TRIM2,RALYL,PCDHB10,PCDHB7,PCDHB3,ARHGEF12,PCDHA1,THRA,NR2E1,RGMB,TRPS1,TUBB2A,TMEFF2,UCHL1,FLRT2,VLDLR,NPDC1,TRIM9,NDRG4,MKRN3,CELF4,FSTL5,CADM2,PARP6,GDPD5,PRDM8,TMEM178A,SCG2,NAV3,SLC17A6,PAK5,NETO1,DPF3,ST8SIA2" Coexpression 19185848-TableS1 Mouse StemCell_Read09_438genes GeneSigDB 8.24E-59 9.53E-55 2.38E-55 2.37E-54 167 299 "ASPHD1,ASIC1,KLHL32,ADCY5,ADD2,KIDINS220,SEMA6A,BIN1,CNIH2,APBB1,APC,APLP1,AQP6,SEMA4G,CADPS,CADM3,CDK5R1,ARHGEF7,CACNA1B,CACNB4,THSD7A,BRSK2,INA,SYNGR3,CDC42,DCLK1,MAGI1,CHGB,SYNPR,RAB33A,NRXN1,FBXO7,CNTN1,SCRN1,DBN1,DNAJC6,ELMO1,SNAP91,SV2B,SV2A,SRGAP3,RABGAP1L,CPEB2,DTNA,EDIL3,SEZ6L2,ATL1,PHF20L1,ELAVL4,RGS17,RCAN2,APC2,CLVS1,TUBB3,TUBB4A,ACTL6B,SGIP1,SORBS1,GABBR1,JPH4,ARPP21,DNER,GPR162,GGT7,AIFM3,PCSK1N,GNG3,GP1BB,GPM6A,STMN2,GRIA4,GRIK2,CELF3,UBE2QL1,KLF12,IGFBPL1,CELF5,DISP2,SCRT2,KCNK2,KCNQ2,KIF5A,KIF5C,KLC1,L1CAM,TTYH2,LSAMP,MAPT,CD200,MYT1,NAP1L2,NEUROD1,NHLH1,NPR2,NPTX1,NRCAM,PDE4D,GPR173,SERPINI1,PIK3R1,PLCD1,SH3KBP1,MINDY2,PKIA,PRKCB,PRKCZ,MAPK10,SPDL1,EML5,NKAIN1,RAB3A,PID1,RBBP6,PRRT2,RNASEL,KLHDC8A,ACER3,ATAT1,RTN1,SCN3A,SCN8A,PPM1E,WDR47,YPEL4,NAPB,SPHKAP,CPEB4,MAST1,SNAP25,PDZRN3,DOP1A,MYT1L,TNIK,KIF21B,KIF1B,NFASC,NACAD,SEPT3,STXBP1,SYT11,PLCB1,SYP,SYT1,MCF2L,CNTN2,ANO4,DMXL2,PCDHB9,GPRIN3,ZFPM2,THRA,ASXL3,TPM3,TRIO,TUB,TUBB2A,MGAT5B,PCDH20,NDRG4,CELF4,MAP3K12,CADM2,GDPD5,STMN4,SLC17A6,PAK5,ST8SIA2" Coexpression M2369 Genes down-regulated during differentiation of Oli-Neu cells (oligodendroglial precursor) in response to PD174265 [PubChem=4709]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.34E-54 8.50E-50 1.70E-50 1.69E-49 367 1080 "CPNE2,TTYH1,SERPINA3,ASIC1,FMNL2,DSCAML1,TMCC3,ADD3,SNX30,KIDINS220,PCDH19,TBC1D14,KIAA1324,WDR35,ALCAM,OGT,ANK3,EP400,LCORL,CNIH2,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,GAS7,LRRC4C,BCAS1,TNRC6C,SHROOM2,SEMA4G,TMEFF1,ARHGAP5,ASPA,ASTN1,DYNLL1,TMEM108,N4BP2L1,ATP6V1G2,BCHE,DST,WASF1,MYRF,BTRC,CFAP410,DDR1,CACNA2D1,THSD7A,KALRN,CAMK2D,TRIM41,HIP1R,ARHGEF25,CD81,REPS2,CDH10,DCLK1,ZNF445,CFL2,SOCS6,CHN2,JAM2,CLCN3,TPP1,FAM189A2,QKI,IGLON5,COL4A5,COL9A1,COL11A2,GAL3ST1,IFFO1,RTTN,ACBD5,CNRIP1,ANKRD44,NCOR1,CLIP3,AATK,CSF1,LRIG1,NCAN,PPP1R16B,RUBCN,USP6NL,DOCK4,HDAC9,KATNAL2,RASSF2,ACY3,LIN54,KIAA0586,DBN1,DCC,DCT,ZEB2,B3GAT3,MFAP3L,KIAA0753,LYPD1,SV2A,RABGAP1L,TMCC2,NR1D2,CPEB2,ABI1,DSCAM,DTNA,ABCC5,ATL1,SGK2,KLHL5,RBM12,MBNL2,PLXNC1,SORBS3,PLEKHA1,ELAVL3,CERCAM,SRPK3,TMEM35A,EPB41L1,EPB41L2,EPS8,NCALD,SPEG,KATNAL1,WAC,TBC1D16,TUBB3,TUBB4A,ATP8A1,CEP78,FCGRT,STRADA,AMOTL2,MEX3B,SEMA4D,WDR83,SORBS1,SPECC1,APOPT1,FAM49B,FUT9,TMEM151A,BRSK1,FYN,PHYHIPL,ZMAT1,GAB1,GALC,TMEM8B,INPP5K,DNER,GATM,FAXC,SRCAP,GFRA2,PCDH17,KIRREL3,RUNDC3A,GLRB,GNAO1,GPD1,GPR17,GPR37,TPPP,RAPGEF1,GRIA2,GRIA4,RFFL,KIF3A,FAM19A2,COQ10A,SOX21,MAP4K5,HAS2,PADI2,FRMD5,HLF,SYNPO,NEGR1,LRRC75A,BTBD17,SHISAL1,NKD1,GAREM2,DOCK7,TJAP1,DIPK1A,ITGA7,JAK2,KCNA1,CDH20,KCNA6,TTYH2,VWA5A,LSAMP,ZFYVE27,MAP6,MAPT,MARK1,MATN2,MBP,CHIC1,LDLRAD3,MGAT3,PPM1L,POC1B,MPP2,SESN3,MT3,MXI1,MIR4697HG,MYO6,NASP,NCAM2,RCOR2,NINJ2,NRCAM,IGSF11,OMG,OPHN1,PAK3,PRTG,PDE4B,PDE4D,ENPP2,SERPINI1,SEMA5B,RETREG1,XRN1,PLEC,PLP1,PLXNB1,PLXNB3,PURG,PDZRN4,SEPT4,EPB41L4B,FA2H,PPARA,PPP2R2B,LRRN3,KANSL1,RASGEF1B,PRKAR1B,RELN,BCAS3,SLC22A23,LRRC49,PIGG,MTMR10,PTPRE,PTPRZ1,PEX5,NKAIN1,RALGDS,RBBP6,ZDHHC14,DUSP15,RFX5,RGS3,RNASEL,TMEM206,PCMTD2,MAP6D1,SOX8,ATAT1,KCNIP3,WLS,S100B,SEMA6D,KIF21A,FAM102A,MYO18A,FHOD3,ST8SIA1,DZIP1,ZNF365,SLC1A3,LIMS2,FAM214B,SIRT2,CCDC88A,SLC15A2,EFHD1,ZFP1,ABTB1,INAVA,KIF13A,LMBRD1,TEX2,UNC5B,DBNDD2,KIF1B,CDK19,NFASC,LHPP,ERBIN,MAPK8IP3,ZSCAN29,PHLDB1,KANK1,ACSBG1,SYT11,PRRC2C,SYT1,ANKRD28,SYT4,ANKRD12,KAZN,CAMSAP2,PDLIM2,ADGRL3,IQCE,ATMIN,EHBP1,WSCD1,KIAA0930,TCF7L2,TRIM2,TCF12,SYNE1,DOCK9,ATP13A2,TGFBR3,SLC44A1,HEY1,DDHD1,CABIN1,TNR,TNS1,TRIO,ZMYND8,RUSC1,TMPRSS5,CA14,RFTN2,TST,TTC3,TMEFF2,HIRA,CADM1,UBE2H,UGT8,FLRT2,FAM181B,NSD2,WRN,RICTOR,ZNF24,ZNF32,FMN2,NDRG4,LYPD6,REEP1,ZSCAN26,PLPPR5,ZFAND5,CADM2,NAV3,URM1,NAV2,FAM13C,AMN1,RTN4,CERS6,NHSL1" Coexpression M17728 Genes down-regulated in brain from patients with Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.19E-50 3.69E-46 6.14E-47 6.10E-46 395 1237 "ABAT,ASIC2,ACHE,ABHD6,C3orf14,ACTN1,ADCY2,SLC12A5,KIDINS220,OGT,ANK3,MAP4K3,ANXA7,APBA2,KCNAB2,APC,APP,TMEFF1,RGS20,CADPS,ASPH,NUMB,ASTN1,DYNLL1,ATP1A2,ATP2A2,ATP2B1,ATP2B2,MTMR9,B3GALT2,ATP6V1G2,ADAM23,ADGRB2,ADGRB3,CDK5R1,SYNJ1,NAE1,SCAPER,BSN,WASF1,CACNB2,CALM1,KALRN,CAMK2A,SLC25A14,RUNX1T1,CLDN10,CCK,LDB2,CCNH,USP6,INA,SYNGR3,CDC27,CDC42,CDH8,CDH10,ZMYM4,CDH18,LARGE1,DLGAP2,CDO1,DLGAP1,CCPG1,CHGA,CHN1,B4GALT6,SLIT2,LHX2,CPNE6,NRXN1,STOML1,CLTC,SULT4A1,CNR1,CABP1,LETMD1,MAGED1,RCHY1,TBPL1,COX4I1,TCEAL2,PREPL,AKAP12,CRMP1,RNF14,CLIP3,CRYM,CS,CSNK1G3,NCAN,PDE4DIP,CNTNAP2,ARHGEF4,RIMS2,NOS1AP,RIPOR2,TOX,MATR3,DGKB,TOMM20,BRINP1,DNAJC6,ELMO1,COPS7A,SACS,SV2B,SV2A,AK5,G3BP2,ARNT2,CHRDL1,DLG2,DMD,HS3ST2,DYNC1I1,CASP8AP2,DNM1L,GOLT1B,EDN3,CNNM1,EIF5,COPS4,TENM1,ELAVL4,BSCL2,ENO2,RCAN2,DMTN,RABEPK,DENND4A,RTN3,GMPR2,NRN1,REEP2,F8,ARMCX1,FAM198B,FABP7,SH3YL1,CACNG3,PTK2B,TUBB3,FECH,OLFM1,FGF13,ACTL6B,FGFR3,FHL1,ATP5PD,UBE2E3,HPCAL4,FOXG1,SEC23B,CAP2,AGAP2,SYNCRIP,DCTN2,TACC2,STAMBP,NPTN,CAMKK2,ATP6V1H,ATP2C1,CSPG5,PNMA2,OGA,GAA,GABBR1,GABRA2,CHL1,GABRB3,CAB39,GAD1,GAD2,GALC,B4GALNT1,GAP43,ATP8A2,NFU1,RUNDC3A,TCERG1,COPS8,GLRB,GLS,TOX3,GLUL,GNAL,GNAO1,GNAS,GNG3,FERMT2,GPM6A,GPR22,PCLO,RAPGEF4,STMN2,GRIA1,GRIA2,BTN2A1,PTPRT,AP4S1,GUCY1B1,WIF1,ACOT7,SCRG1,HNRNPK,HPCA,HSF2,HSP90AA1,SMAP1,HTR2A,IDH3B,IGF1,DIPK1A,ITPKA,JAK2,KCND2,KCNF1,KCNJ3,KCNK1,KCNN2,KCNQ2,KIF2A,KIF5C,KIT,KLC1,IPO5,L1CAM,MATK,TM6SF1,LRP1B,SHC3,MEF2C,CD200,THYN1,SCG3,TAGLN3,FXYD7,NAP1L2,FXYD6,NDUFA5,NEFM,NEFH,NELL1,NELL2,NEUROD1,SLCO1C1,NNAT,NPY,NRGN,OMG,OPA1,SNTG1,PAK3,PCMT1,PCSK1,PCSK2,PDCD2,PDE2A,PDE4B,PDE4D,PENK,CDK14,ABCB1,SERPINI1,SNX10,FAM216A,LRP12,PSAT1,SCHIP1,MAGEL2,FSD1,PPP2R2B,LRRN3,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PRKAR1B,PRKCB,MAPK9,MAPK10,DIRAS2,SNRK,ELOVL2,PTN,PTPRE,PTPRN2,PTX3,RAB3A,RAP1GDS1,OXR1,RFX5,RGS4,RGS7,RIT2,SEC61A2,NUDT11,ROBO1,RPE,RPL15,FBXW7,RPL38,MEG3,KCNIP1,CLIP1,RTN1,ATXN1,SCN2A,SCN3A,SCP2,SFPQ,HSPA4L,SCG5,CNKSR2,BCAN,CCDC92,SEC31A,DZIP1,SLC4A3,SLC6A1,PKNOX2,SHANK2,ELMO2,SORCS3,SNAP25,SNCA,FAIM2,USP33,SCN3B,SON,MYT1L,NMNAT2,GLT8D1,PEG10,BEX1,KIF1B,DDN,SRPK2,CLASP2,SST,ELOVL4,STX1A,STXBP1,NSFL1C,VAMP1,ARHGEF9,PLCB1,SYN1,SYN2,SYT1,SYT5,TAC1,PJA1,TAF9,ADGRL3,DMXL2,WDR7,PSD3,PUM2,ATP13A2,ZMAT3,AKTIP,HEY1,TMOD1,R3HDM1,SEZ6L,TRO,TRPC1,RUSC1,TTC3,TUBB2A,UBC,RPRM,UCHL1,DNAJC12,PITPNB,FLRT2,VLDLR,VSNL1,USP32P2,NDRG4,ZNF142,ZNF184,SH3GLB2,MFF,LRP8,KCNAB1,RTN4,CAMK1G,ACTR3B,NETO2,AP3B2,JPH3" Coexpression M10371 "Set 'H3K27 bound': genes posessing the trimethylated H3K27 (H3K27me3) mark in their promoters in human embryonic stem cells, as identified by ChIP on chip." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.72E-48 1.99E-44 2.84E-45 2.82E-44 364 1117 "TTYH1,ASIC1,FAM43B,CSMD2,CSMD3,ADARB2,GALNT16,DSCAML1,SLITRK1,ADCY8,SORCS1,LRFN2,SLC24A4,KLHL13,KIAA1324,ARHGAP20,AMPH,LRCH2,LGR5,SPTBN4,ZFYVE28,ARNTL,RGS20,ASCL1,PDE8B,BRINP2,CHRD,ASTN1,ATP1A3,NOL4,TTLL9,ADAM15,ADGRB2,RGS9,ARHGEF7,CACNA1G,CDK5R2,MMD2,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB4,CAMK2B,SYT6,CH25H,CBLN1,INA,CD38,ENTPD2,NEURL1,DGKI,LRBA,REPS2,DCLK1,CRLF1,CIART,CHN2,SLIT2,LHX2,RAB33A,NRXN1,TMEM59L,VAX2,CNTFR,COL4A5,ANKRD35,SLC25A27,COL9A2,NRG2,CNRIP1,MFSD4A,CRMP1,SLC32A1,SNCAIP,CSF1,FEZ1,CHD5,RIMS4,PDE4DIP,RASGEF1C,CTNND2,FRMPD4,DGKG,DCC,ZEB2,FBXO25,SV2B,SPOCK3,CHRDL1,DLX1,GRIN3A,HS3ST4,HS3ST2,DYNC1I1,DPP6,DTNB,EBF1,CNNM1,HEYL,EFNA3,YAF2,EGR3,PLXNC1,TMEM132E,ELAVL2,ELAVL3,EN2,OLIG2,SEZ6,EPHA5,EPHB1,RAB9B,ERBB4,RCSD1,NRN1,CACNG3,ZIC4,FGF11,ACTL6B,PRKAG2,HPCAL4,FOXG1,FOXF2,AGAP2,ZMYND15,PSD2,RASL10A,DACH2,FUT9,TPPP3,TMEM151A,TBR1,PHYHIPL,GABRA2,GABRA4,ILDR2,GAD2,B4GALNT1,NKX6-2,SRRM4,DNER,GBX2,PCDH17,GHR,C1QL1,KIRREL3,NTNG2,INSM2,DCLK2,RAB40B,GNAO1,PRUNE2,GPM6B,PRLHR,GPR12,GPR26,RAPGEF4,STMN2,GRB10,GRIA2,PARD3B,GRID1,GRIK1,GRIK3,GRIN1,GRIN2D,GRM7,PTPRT,GSN,GUCY1A1,ATOH8,HBA1,IGSF21,PADI2,C1orf94,FRMD3,HPSE2,TLX1,NEGR1,HSPA1L,SHISA6,SOWAHA,IGFBP1,NIM1K,SCIN,HES5,BRINP3,RIPPLY2,LRRTM1,ITPKA,SLC35G1,KCNA1,KCNC2,KCND3,KCNF1,GPR62,KCNH1,KCNJ3,KCNJ4,KCNJ9,KCNJ10,KCNK2,KCNK3,KCNMA1,KCNQ3,CAMK2N2,LMO1,C1orf194,MAP6,MAPT,IL17D,MEIS1,ADAM22,MT1M,MT3,DDX25,RSPO2,HS6ST3,LAYN,RTL5,PABPC1L2A,FXYD7,NBL1,NCAM1,NEFM,NEFH,NELL1,NEUROD1,NEUROD2,NFIA,NFIX,NKX2-2,NOVA2,NPTX1,NRGN,NTRK2,GPR88,PAX6,DPY19L2P2,PCDH8,PCSK2,PDE1B,PDGFRA,SLC10A4,PENK,TMOD2,ST8SIA5,PLEC,PLP1,PMP22,POU3F2,POU3F4,IRX1,PRKCB,MAPK4,DCHS2,CNNM2,SIDT1,PLPPR1,PTHLH,ELOVL2,PTPRN2,SUSD4,RASGRF1,FEZF2,CRTAC1,DUSP15,RFX4,RGS10,TTLL7,EPHA10,RIMKLA,RPS6KA2,STK32B,SOX8,KCNIP2,RXRG,RYR3,AMER2,SEMA6D,LRFN5,SCN4B,SMPD3,ELMOD1,SLC30A10,IL17RB,SH3GL2,PPM1E,FRMPD1,SHC4,SLITRK3,BCAN,SLC1A2,FAM81A,SLC6A1,PKNOX2,SLC6A11,TRIM67,LGI3,SLIT1,GKAP1,SORCS3,PDZD2,UNC5B,SPTB,CLSTN2,COLGALT2,MESP1,SSTR1,SSTR2,NKAIN2,PHLDB1,STX1A,ABCC8,ADAMTS17,ASTN2,TAC1,TACR1,ROBO3,TAL1,CNTN2,ADGRL3,WSCD1,SATB2,AZIN2,SYNE1,CHST8,HHIP,ARL10,HEY1,ICAM5,NR2E1,TNFRSF1B,PRRT1,CSMD1,DOK6,TRH,FNDC5,ANKRD20A2,TTPA,PRR18,TMEFF2,OSBP2,FLRT2,WNT7A,KCNK12,ZIC1,TRIM9,ZBTB16,REEP1,DPYSL5,LAMP5,SLC30A3,CA10,SLC30A4,SEMA3B,NAV2,SLC17A7,KCNAB1,TMEM163,SLC17A6,DPF3,ST8SIA2" Coexpression M2115 Genes correlated with proneural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-46 2.94E-42 3.68E-43 3.65E-42 111 177 "DPF1,TTYH1,ABAT,KLRC4,CDC7,NR0B1,ALCAM,CASK,TMEFF1,ASCL1,ATP1A3,NOL4,ADGRB3,BCL7A,CDK5R1,WASF1,DGKI,ARHGAP33,CLGN,RAB33A,NRXN1,NRXN2,VAX2,CNTN1,CRMP1,CSNK1E,MATR3,DBN1,ZNF804A,ZEB2,SRGAP3,DPP6,TMEM35A,OLIG2,EPB41,EPHB1,NCALD,AMOTL2,C1orf61,DPYSL4,CSPG5,DLL3,GABRA3,C1QL1,TOX3,PCDH11X,CBX1,GNG4,GPM6A,GPR17,LPAR4,GRIA2,IL1RAPL1,KAT7,RNFT2,CELF3,RBPJ,KLRC3,STMN1,MAP2,MAPT,MMP16,SCG3,MYT1,FXYD6,NCAM1,NKX2-2,P2RX7,PAK3,DUSP26,NLGN3,PURG,NKAIN1,SEC61A2,ATAT1,SATB1,SCN3A,LRRTM4,ZNF821,PPM1E,FERMT1,FHOD3,BCAN,CXXC4,MAST1,SORCS3,INAVA,TMCC1,SOX2,KIF21B,SOX10,SOX11,BEX1,CLASP2,ZC4H2,ARHGEF9,CAMSAP2,ADGRL3,CRB1,SEZ6L,TTC3,FLRT1,ZNF711,REEP1,ZNF184,CA10,STMN4,MVB12B,HRASLS,PAK5,ZNF248" Coexpression M9898 Set 'Suz12 targets': genes identified by ChIP on chip as targets of the Polycomb protein SUZ12 [GeneID=23512] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.14E-42 3.63E-38 4.03E-39 4.01E-38 332 1038 "TTYH1,DGCR6,ASIC2,ABHD6,FAM43B,CSMD3,ADARB2,DSCAML1,SLITRK1,ADCY8,SLC12A5,SORCS1,PTCHD1,SLC24A4,GPR158,NR0B1,KIAA1324,ARHGAP20,LRCH2,LCORL,GAS7,LGR5,ZFYVE28,RGS20,ASCL1,PDE8B,BRINP2,CHRD,ASTN1,CADM3,NOL4,ADGRB2,ARHGEF7,CACNA1G,CDK5R2,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB4,HAP1,NGB,SYT6,CH25H,CBLN1,INA,CD38,DGKI,REPS2,NOG,CRLF1,SLIT2,LHX2,RAB33A,TMEM59L,VAX2,CNTFR,COL4A5,COL9A2,TCEAL2,NRG2,CNRIP1,MFSD4A,CRHBP,CRMP1,SLC32A1,GDA,CSF1,FEZ1,LRRC3B,PDE4DIP,SLITRK5,CTNND2,FRMPD4,DGKG,SPOCK2,DCC,ZEB2,LYPD1,PLPPR4,SV2B,SPOCK3,DLX1,GRIN3A,HS3ST4,OLIG1,HS3ST2,USP3,DPP6,EDN3,CNNM1,RASGRP1,EFNA3,EGR3,TMEM132E,KCTD3,ELAVL3,EMX2,EN2,OLIG2,EPHA5,EPHB1,RAB9B,EPS8,ERBB4,RCSD1,ZIC4,DLC1,ST3GAL6,FGF13,TMEM164,HPCAL4,FOXG1,ZMYND15,AFF2,RASL10A,DACH2,TPPP3,TBR1,PHYHIPL,MEGF11,GABRA2,GABRA4,ILDR2,GAD2,ZMYND11,B4GALNT1,NKX6-2,ACSS1,DNER,GATM,GBX2,ALDH1L1,TUBA8,GFRA1,GFRA2,PCDH17,GHR,KIRREL3,NTNG2,PCDH11X,MAP7D2,INSM2,PCSK1N,DCLK2,RAB40B,GNAS,GPM6B,PRLHR,GPR12,RAPGEF4,STMN2,GRIA2,GRID1,GRIK1,GRIK3,GRIN2D,GRM7,PTPRT,IL1RAPL1,SOX21,GUCY1A2,GUCY1A1,ATOH8,CELF3,HBA1,IGSF21,TOX2,FRMD3,HLF,HPSE2,TLX1,TCEAL6,SHISA6,NKD1,BRINP3,INSM1,LRRTM1,ITPKA,ITPKB,KCNA1,KCNC2,KCND3,KCNH1,KCNJ3,KCNJ5,KCNK2,KCNMA1,KCNQ3,SYTL4,C1orf194,MAP6,MAPT,MID1,MT1M,RSPO2,HS6ST3,LAYN,NEXMIF,PABPC1L2A,NBL1,NCAM1,NDP,NEFM,NEFH,NELL1,NEUROD1,NEUROD2,NFIA,NFIX,NKX2-2,NOS1,NPTX1,NRCAM,NTRK2,NTRK3,GPR88,PAX6,DPY19L2P2,PCDH8,PDGFRA,SLC10A4,PENK,TMOD2,PLEC,PMP22,TRHDE,POU3F4,IRX1,MAPK4,DCHS2,SIDT1,PLPPR1,PTHLH,EML5,RIPOR1,TMEM255A,SUSD4,RASGRF1,RASGRF2,DBX2,FEZF2,CRTAC1,RGS10,RORB,EPHA10,RIMKLA,STK32B,WLS,RXRG,RYR3,AMER2,SEMA6D,LRFN5,SCN4B,SCP2,ELMOD1,SLC30A10,HSPA4L,PPM1E,FRMPD1,SHC4,SLITRK3,ST8SIA1,SLC1A2,ZNF365,FAM81A,SLC6A1,PKNOX2,SLC6A11,SLC8A3,TRIM67,LGI3,SLIT1,SORCS3,PDZD2,SOX1,SOX3,SOX10,UNC5B,SPTB,C11orf87,CLSTN2,COLGALT2,MESP1,THSD1,SSTR1,SSTR2,PHLDB1,ABCC8,PLCB1,ASTN2,TACR1,ROBO3,TAL1,ADGRL3,TBL1X,CHST8,HHIP,HEY1,ICAM5,TLL2,TNFRSF1B,CSMD1,PARD3,DOK6,PRMT8,TRH,ANKRD20A2,TMEFF2,AMOT,FLRT2,MGAT5B,VIPR2,WNT7A,KCNK12,ZIC1,ZNF711,TRIM9,ZBTB16,DPYSL5,LAMP5,SLC30A3,CA10,SLC30A4,NAV2,KCNAB1,TMEM163,ADAMTSL3,KLHDC1,DPF3,ST8SIA2" Coexpression M2019 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.36E-39 2.74E-35 2.74E-36 2.72E-35 220 589 "TTYH1,KCNH8,ACHE,EMILIN3,ACTN2,GPRIN1,ELFN2,DSCAML1,SLC12A5,UNC5A,DISP3,C1QTNF4,MARCH4,GOLGA7B,ALK,KCNT1,DOC2A,DPP10,APBA2,AMER3,SHTN1,SLC7A14,ASTN1,ATP1A3,ATP2B2,CADM3,TTC9B,ADGRB1,ADGRB3,FGF17,BSN,CDK5R2,CA4,CACNA1E,CALB1,CALB2,CABP7,DIRAS1,NGB,CAMK2B,VSTM2A,BRSK2,CCKBR,CDH8,DLGAP2,CACNA2D2,CHGA,CHGB,CHRNA4,CHRNB2,NRXN2,TMEM59L,MYRIP,CRHBP,SLC32A1,C1QL2,CRYM,AATK,LRRC3B,PHACTR3,RASGEF1C,PPP1R16B,SLC45A1,DCC,DNAJC6,ZNF804A,TMEM130,NTM,OLIG1,HS3ST2,DSCAM,ST8SIA3,EEF1A2,CNNM1,ELAVL2,OLIG2,RASGRP2,TUBB4A,FGF11,FGF12,FGF14,ACTL6B,FOXG1,PSD2,CSPG5,DLL3,NRG3,GABRA5,GAD1,NKX6-2,GALR1,ATP8A2,SRRM4,CPLX2,CPLX1,C1QL1,RUNDC3A,AIFM3,INSM2,LUZP2,GP1BB,GPR12,GPR26,RAPGEF4,GRIA2,GRID1,GRIK3,GRIN2C,GRM1,PTPRT,GSTT2,TMEM179,IGSF21,PADI2,HMX1,IGFBPL1,TLX1,SHISA6,SOWAHA,KNDC1,HES5,INSM1,KCNA2,CDH20,KCNB1,KCNC1,KCND3,KCNH1,KCNJ10,KCNQ2,KCNQ3,ADAM11,CPNE9,NELL1,NEUROD1,NEUROD2,NKX2-2,HCN1,NTRK3,OXTR,PCDH8,PIK3CD,NECAB2,PACSIN1,NXPH1,POU3F2,PPP2R2C,VSTM2L,SKOR1,PRKCZ,RELN,PSD,PTPRN2,IQSEC3,FEZF2,CRTAC1,ZMAT4,RFX4,LGI2,SGSM1,RIMKLA,STK32B,PAQR6,KCNIP1,LRFN5,SCN8A,ASIC4,SLITRK3,BCAN,SLC6A1,SLC6A7,SLC6A11,SLC8A2,SLIT1,MAST1,SORCS3,SNAP25,SNCB,SCN3B,SOX1,SOX2,LHFPL4,RAP1GAP2,SST,FCHO1,ABCC8,TMEM150C,TACR1,MCF2L,TAL1,CNTN2,WSCD1,ACSL6,VWC2,PHF24,TMEM151B,LEFTY2,THBS4,NR2E1,PRRT1,CSMD1,SEZ6L,PRMT8,TRH,FNDC5,LRTM2,UGT8,MGAT5B,RBFOX3,WNT7A,SLC13A3,PLPP4,CELF4,LAMP5,CA10,PRDM8,SLC17A6,NETO1,CBLN2,JPH3" Coexpression M2892 Genes up-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 5.66E-38 6.55E-34 5.96E-35 5.92E-34 90 143 "SLC12A5,NME5,SPARCL1,ANK2,ANK3,AQP4,ASPA,ATP1A2,NOL4,CDK5R1,CALB1,MAP7,DLGAP2,CDR1,CHGA,CHGB,NRXN1,TCEAL2,CP,CRYM,ERC2,SNAP91,SV2B,AK5,DYNC1I1,RCAN2,ETV1,NRN1,TUBB4A,ST3GAL6,HPCAL4,SORBS1,NSG2,NSG1,PNMA2,GABRA1,GABRA5,GABRB1,GAD1,ARPP21,GAP43,GATM,GLDC,GPM6A,GPR19,GPR37,RAPGEF4,GRIA2,GRIK2,GRM5,WIF1,KIF5C,KIT,MEF2C,SCG3,NAP1L2,NRCAM,PCDH9,SERPINI1,PLCL1,PLP1,PMP2,RELN,SLC6A15,RIT2,NUDT11,TMEM100,RTN1,SATB1,SCN2A,SCG5,CPEB3,SLC1A3,SLC6A1,LIMCH1,SNAP25,NMNAT2,LMO3,EPB41L3,PLCB1,SYT1,WSCD1,TRIM2,HEY1,TMOD1,VIPR2,TRIM9,CAB39L,PLSCR4,FZD3" Coexpression 19605494-TableS2 Mouse Skin_Driskell09_1477genes GeneSigDB 4.56E-35 5.27E-31 4.39E-32 4.37E-31 278 872 "TTYH1,KCNH8,ABHD6,TMCC3,GALNT13,AXIN2,ERMN,OSBPL1A,OSBPL6,C1QTNF1,LTBP4,OGT,CDC42BPA,MAP4K3,ANXA7,APBB2,VAT1L,PRX,ARNTL,ASPA,ASPH,TMEM108,SLC4A4,ATP2B1,RNF182,KIF1A,DOCK11,BCHE,DST,ARHGEF7,IL33,MMD2,CACNA1B,THSD7A,CAMK2D,BRSK2,LDB2,CBFA2T2,REPS2,CDH2,CDH10,DCLK1,LGI1,MAGI1,DLGAP1,NOG,ADGRG1,CHN2,PLEKHB1,SLIT2,NRXN1,TJP2,FAM19A5,CNTN1,SLC4A7,ABI3BP,CP,SLC35F1,RBM39,ABCG1,LRIG1,FEZ1,MICAL2,VCAN,FAM169A,SLITRK5,ECE2,HDAC4,RASSF2,KCTD8,DAPK1,DCC,DNAJC6,PLEKHM1,MFAP3L,RHOBTB1,SNAP91,SPOCK3,NTM,ARNT2,GRIN3A,RAB39B,DMPK,DMTF1,DNM1L,PHF20L1,MBNL2,PLEKHA1,SRPK3,VPS13B,LRRC17,EPHA5,ETV1,RCSD1,AMZ2,ATP8A1,CHST15,FGF1,FGF14,CAP2,FOXM1,FOXO3,FOLR2,NBEA,SORBS1,SPECC1,CAMKK2,MEGF10,CHL1,GART,DNER,GATM,GCNT2,GHR,PPARGC1A,SPIN1,PCDH11X,GNAS,PSRC1,GPD2,GPM6B,LPAR4,RAPGEF4,GRIA2,GRIK2,WIF1,NEGR1,IGF1,LRRTM1,METTL21A,KCNA1,KCND2,KCNJ10,KCNQ3,LIMS1,LSS,MAG,MAPT,MBP,MEIS1,MEST,MMP17,MN1,CCDC80,MYT1,NCAM1,NCAM2,NELL1,NFIA,NFIX,NNAT,NTRK2,NUCB2,IGSF11,P2RX7,PAK3,PBX1,PCDH9,PCSK5,PRTG,PDE1C,PDE2A,PDE3A,TMOD2,DUSP26,SERPINE2,NALCN,RETREG1,PLCL1,PLP1,PLXNB3,PURG,PMP2,STRN3,RC3H2,SCHIP1,PRRX1,FA2H,FAT3,LRRN3,PRKAR1B,MASP1,RELN,SLC22A23,GDPD2,MDGA2,PTH1R,PTPRD,PTPRZ1,PTX3,TMEM255A,FAM184A,BEND5,KHDRBS2,DUSP15,FIGN,RFX3,RGS10,TTLL7,MRPS18A,ZFHX4,RORB,FBXW7,LRRK2,LGR4,HUNK,RYR3,S100B,MAPK12,SCN4B,LRRTM4,SCN8A,HSPA4L,KIF21A,ASAP3,NTNG1,FHOD3,NLGN1,ANKRD6,WDR37,SLC1A3,SLC6A1,SLC8A3,EFHD1,SNCA,PALLD,FAM126B,UNC80,TNIK,SPP1,ERC1,ATP10B,STOX1,NKAIN2,SS18,RGL1,SULF2,FGD4,ARHGEF9,TMEM150C,TAL1,ADGRL3,TCF4,CUX2,TCF7,CHST8,HHIP,CDH22,SLC44A1,ASXL3,DDHD1,ZFP91,PRRT1,RGMB,AMACR,SSBP2,TTPA,SLAIN1,VAV2,VLDLR,TSPAN11,P2RY12,RICTOR,ZIC1,TRIM9,LYPD6,CELF4,ZBTB16,FTSJ1,ZFAND5,CADM2,ADAMTS9,SEMA3B,NAV3,NAV2,RGS7BP,JMJD1C,SSPN" Coexpression M2110 Genes whose expression significantly and positively correlated with the density of CALB1-positive [GeneID=793] GABAergic interneurons in the BA9 brain region across all subjects with psychiatric disorders. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.32E-34 3.84E-30 2.96E-31 2.94E-30 200 548 "ABR,ACTN1,ADAR,SLC12A5,OSBPL1A,DOC2A,AMPH,ANXA7,APLP1,FAM131A,MADD,ATP1A3,ATP2A2,ATP2B1,MTMR9,ATP6V0A1,ADAM23,ADGRB2,SYNJ1,CACNA1A,CALB1,CALM1,KALRN,CAMK2B,CAMK2G,CANX,CCK,LDB2,INA,SYNGR3,DCLK1,CHGA,CHGB,CHN1,B4GALT6,NRXN1,CLTB,MAGED1,PREPL,CRHBP,CRMP1,CLIP3,CRYM,ATRNL1,SOCS5,SLITRK5,PPP1R16B,PUM1,CX3CR1,DOCK4,KIAA0513,TM9SF4,DGKB,TOMM20,SCRN1,BRINP1,DCTN1,ELMO1,COPS7A,CEP170,G3BP2,DLG3,DNM1,DYNC1I1,DPP6,ABCC5,ANKRD46,OPTN,EFNB3,EGR3,EIF5,ENO2,RCAN2,NCALD,CACNG3,PTK2B,TUBB3,SEC24B,FHL1,UBE2E3,FOXG1,CAP2,NPTN,KHDRBS3,NSG2,STAU2,PNMA2,SARAF,OGA,GABRA1,GABRA2,GABRA5,CHL1,GABRG2,NCKAP1,SYT17,RUNDC3A,COPS8,GLRB,GNAS,PRUNE2,GPM6A,STMN2,GRIA2,GUCY1B1,ACOT7,HMGCR,HNRNPK,HPCA,HSP90AA1,HTR2A,IDH3A,IDH3B,KCNF1,KCNK1,KLC1,MAN2A2,MAPT,MBNL1,CD200,LYRM9,NDUFA5,NELL1,NELL2,NNAT,NPY,NPTX1,NRGN,OMG,OPCML,DPY19L2P2,PCDH8,PCMT1,PCSK1,PDE2A,PFKP,SERPINI1,PKM,SCHIP1,NECAB2,PRKACB,MAPK9,PSMA6,PTPRN2,SLC6A15,RGS4,RGS7,RIT2,SLC25A36,RTN1,SARS,SCAF8,SCG5,CNKSR2,CLSTN1,ZNF365,BTBD3,WDR47,SNAP25,SNCB,NMNAT2,MYCBP2,LMO3,SRPK2,SST,NCDN,STX1A,STXBP1,SYT11,ARHGEF9,SYT1,TAC1,DDHD2,CAMSAP2,KIAA1107,EHBP1,WDR7,PHF24,RALYL,PUM2,TIAM1,ICAM5,BEX4,RUSC1,TTC3,TUBB2A,UBC,UCHL1,VSNL1,NDRG4,REEP1,ZFAND5,RNF103,SCG2,SLC17A7,KCNAB1,RTN4,HNRNPA3,CAMK1G,CERS6" Coexpression M1954 Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.06E-32 2.39E-28 1.70E-29 1.69E-28 168 434 "ASIC2,ASIC1,ACHE,EMILIN3,FAM43B,ELFN2,ADORA2A,DISP3,C1QTNF4,KCNT1,DPP10,ANK1,SEMA7A,CPNE5,ATP2B2,ATP2B3,TTC9B,ADGRB1,ADGRB2,JAZF1,CACNA1I,CACNA1G,BSN,CACNA1D,CABP7,CAMK2B,SYT6,BRSK2,CBLN1,SHISA7,CCK,CCKBR,DLGAP2,CLGN,NOG,CRLF1,CACNA2D2,CHRNB2,SLIT2,NRXN2,TMEM59L,COL9A2,MYRIP,SLC32A1,C1QL2,RIMS4,PDE4DIP,RASGEF1C,DBN1,ZNF804A,AK5,HS3ST2,DSCAM,CNNM1,EFNA2,TMEM132E,EPHB1,RASL12,CORO2B,FGF12,PSD2,DPYSL4,DLL3,HHIPL1,NRG3,PHYHIPL,GABRA4,GABRA5,NKX6-2,ATP8A2,CYP46A1,C1QL1,GLDC,AIFM3,PRLHR,CCDC184,GRB10,GRIA2,C1QL4,GRID1,GRIN2C,GRM1,PTPRT,PTPN5,IGSF21,NXPH2,HMX1,IRF8,NKD1,HES5,SLC6A17,ITPKA,KCNA2,KCND3,KCNH1,KCNH2,KCNJ4,KCNMA1,KCNQ2,KCNQ3,L1CAM,LMO1,STK32C,NEFH,NELL1,NELL2,NEUROD1,NPTX2,NTRK3,OXTR,PDE1B,TRHDE,SDK2,NECAB2,PACSIN1,IRX1,VSTM2L,SKOR1,RELN,PTPRB,FAM184A,FEZF2,LGI2,DRAXIN,SCN4B,SCN8A,ASIC4,SLC30A10,STUM,ARX,SLITRK3,BCAN,ABLIM3,SLC6A1,SLC6A7,SLC8A2,LGI3,SLIT1,MYO16,MYCBP2,NPAS3,CLSTN2,SSTR1,EPB41L3,ABCC8,PDLIM2,CNTN2,WSCD1,PHF24,TMEM151B,PCDHAC2,CDH22,SEZ6L,DOK6,PRMT8,NEIL2,FNDC5,NTSR2,LRTM2,FAM155A,RBFOX3,ZIC1,CELF4,ZBTB16,LAMP5,PLPPR5,TMEM178A,JPH3" Coexpression 17880687-TableS2 Human Embryo_Heim07_2325genes GeneSigDB 9.47E-31 1.10E-26 7.30E-28 7.26E-27 413 1565 "CLK4,EMILIN3,CSMD2,NDRG2,FMNL2,TMEM132B,ADCYAP1R1,ADD2,AXIN2,NLGN4X,PCDH19,TBC1D14,TAOK1,SEMA6A,SPOP,SYT13,PDZD4,BIN1,CDC42BPA,PKP4,CNTNAP1,APBB2,ALS2,PHYHD1,VAT1L,SHROOM2,CDC14B,IGDCC4,CADPS,DACT3,RASL11B,DDX3Y,STX16,CADM3,KIF1A,BACH1,NRP2,PROM1,SYNJ1,CASTOR3,SGCE,FOXK1,CA12,DDR1,CACNA2D1,THSD7A,PTBP2,RUNX1T1,CBLN1,CLDN10,KYAT1,CCKBR,INA,MYOM2,SEPT7,CDC42,CRLF1,CHN2,PLEKHB1,JAM2,SLIT2,KMT2C,TMEM59L,FAM189A2,TJP2,VAX2,ABCG2,FAM19A5,HECTD1,NIPBL,HOMER3,TMEM155,ARHGEF6,CNR1,AKAP7,ARMC8,COL9A3,AHCTF1,BAG4,FAM171B,C2CD2,RBM39,CREB5,SNCAIP,TENM4,FEZ1,CSNK1G3,SIPA1L1,PDE4DIP,CNTNAP2,CTH,HDAC9,FGFR1OP2,GAPVD1,TOX,TBC1D5,MATR3,TMEM170A,DAPK1,BRINP1,DBT,PITPNC1,YTHDC1,ZEB2,ZBTB24,CNIH3,MAGI2,FBXO25,LYPD1,GSDME,SMG7,RABGAP1L,MTX3,FAM107B,DYNC1I1,NR1D2,DPP6,RCAN1,DTNA,DUSP9,DNM1L,ST8SIA3,TSPAN5,EDN1,ATL1,FEM1B,FCF1,YAF2,FAM13A,EGFR,TMEM132E,TUBD1,EPB41,EPB41L1,EPB41L2,ERBB2,EFS,TMEM74,RTN3,RASL12,FABP7,TBC1D16,ACSL4,EFEMP1,DLC1,OLFM1,AMOTL2,POLK,MEX3B,SEMA4D,FLT1,TACC2,SORBS1,TMEM107,UFM1,PDLIM5,NPTN,CSPG5,B3GAT1,MPP6,GABBR1,ZNF44,GABRA5,GAD1,AHCYL1,NEK6,IQGAP2,CPLX2,IGSF5,GCNT2,ARFIP1,SESN1,PCDH17,RND1,GLI2,GLS,TOX3,TNRC6A,ZNF638,KIAA1958,KDM2B,HTATSF1,GNAO1,GNAS,GNG3,FERMT2,LNX1,GPD2,PRUNE2,GPM6B,LPAR4,NUDT21,EML4,DIDO1,ADAMTS8,NR3C1,KIF3A,ATOH8,RASSF8,HAS2,TOX2,ZHX1,BACH2,MIER3,AGFG1,IFI16,RBPJ,IL6ST,ZNF678,ITPKB,KCNJ4,KCNN2,L1CAM,CAMK2N2,LIMS1,PAXBP1,SMAD1,SMAD9,MARK1,AQP11,MBNL1,CHST6,LDLRAD3,MDM4,SHC3,MEIS1,MEIS2,MID1,PPM1L,MN1,CD200,MPP2,TAGLN3,DDX25,MXI1,MYH6,MYO6,RTL5,FXYD6,NASP,NCAM1,NCAM2,NEFH,CCDC13,NFIA,NFYA,NODAL,NPTX2,SLC11A2,PBX1,CDK18,PRTG,PDE4B,PDGFRA,GNG2,PFKFB2,SEMA5B,PIK3C2A,ZNF655,SNX10,GPSM2,PLP1,MTRF1L,PURG,EPB41L4B,FAT3,PPP1R1A,CRLS1,PPP3CA,KANSL1,PRKAB2,CEP41,PRODH,SLC22A23,SYTL2,GON4L,PTPRG,PTPRZ1,ZSCAN2,TTC13,USP47,ZNF493,ARID4A,VEPH1,RET,FIGN,RFX3,RGS3,RGS4,PRIMA1,RIC8B,RPRD1A,EXD2,GSTCD,MRAP2,RPE,BAALC,SPIN3,ACER3,STK32B,HUNK,RTKN,CLIP1,AP1AR,AMER2,MAPK12,SEMA6D,SATB1,ATXN2,SCN4B,FNIP1,IL17RB,PEAR1,ASRGL1,TRA2B,RASA3,FERMT1,ASAP3,CHD9,CNKSR2,CCDC92,ANKRD6,SLC1A6,URGCP,PREX2,FAM214B,KANSL3,SEPHS1,CCDC88A,SHANK2,KBTBD4,SLC15A2,CPEB4,GKAP1,LIMCH1,PALLD,PDZD2,SOX3,KIF21B,SOX11,DOK5,LHFPL4,PEG10,SPTAN1,TSPYL2,RBM26,LMO3,LRRC4,NXT2,SOX21-AS1,MPRIP,GSE1,KLHL7,FGD4,PRRC2C,SYNE2,TMEM150C,SYN2,KAZN,PDLIM2,CNTN2,TBL1X,KLHL4,WSCD1,TCF4,TCF7,PSD3,OBSL1,PCDHAC2,AHCYL2,TEK,LEFTY2,AKTIP,SLC44A1,TIAM1,TLL2,LRRC8A,FAM124A,TP53BP1,TPM4,RGMB,TRH,TRIO,TRPS1,FNDC5,DCBLD1,RPRM,UBE2H,FLRT2,CCDC136,VSNL1,RBFOX3,WIPF1,SLC13A3,SF1,ZIC2,KCNT2,ATP6V0E2,PLPP4,SYNC,WNK1,PMEPA1,MAP3K12,SHD,STOX2,NAV2,TMEM163,RTN4,UBE3B,FBXO36,JMJD1C,SSPN,SPATA13" Coexpression 19168792-TableS3 Human Leukemia_Figueroa09_1035genes GeneSigDB 5.31E-30 6.14E-26 3.84E-27 3.81E-26 244 774 "ADCY8,SORCS1,PTCHD1,KIDINS220,HECW2,KCTD16,OSBPL1A,C1QTNF3,CDC42BPA,ALS2,LRRC4C,LGR5,AQP4,SPTBN4,CADPS,ZNF582,NOL4,FGF17,NRP2,BMP7,ARHGEF7,CACNA1G,CDK5R2,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,KALRN,SYT6,VSTM2A,MAP7,CDH8,L3MBTL4,MAGI1,CDO1,CHGB,RAB3C,DLGAP3,TMEM155,CNN3,TCEAL2,ZFP28,HAPLN1,C1QL2,SNCAIP,RGS6,FEZ1,SUSD5,GALNT9,CHD5,VCAN,PITPNM3,PYGO1,FRMPD4,KIF26A,MATR3,PABPC5,DCC,ZNF804A,LYPD1,GRIN3A,DRD1,ATN1,TMTC1,CELSR3,ELAVL2,ELAVL3,EML1,EPHA5,EFS,ZNF549,ETV1,NRN1,ZIC4,TAOK3,CEP78,FECH,UBE2E3,FOXG1,DPYSL4,FUT9,ADGRA1,DKK3,CHL1,GABRB3,B4GALNT1,GALR1,SALL3,NCKAP1,SYT17,CPLX2,GFRA1,PCDH17,PPARGC1A,MALT1,MAP7D2,PRUNE2,PRLHR,GPR26,STMN2,GRIA2,GRM1,GRM3,GRM7,PTPRT,RNF165,SOX21,GUCY1B1,TMEM179,IRAK3,IGSF21,NXPH2,FRMD3,MIER3,HLF,HPSE2,HMX1,SMAP1,IRF8,SOWAHA,ZIC5,IL11RA,BRINP3,INSM1,LRRTM1,KCNA4,KCNJ9,KCNN2,KCNQ3,KTN1,MAP6,MARK1,CHST6,SCG3,MDGA1,MYH7,MYO7A,NDP,NEFM,NELL1,NEUROD1,NKX2-2,NOVA1,NRCAM,HCN1,OPHN1,OXTR,PCDH8,PDYN,GPR173,PENK,GDAP1L1,PCDH18,PSAT1,PRRX1,NXPH1,POU3F2,POU3F4,PPP1R1A,PCDHB17P,PPP2R2C,PRKCZ,DIRAS2,PROX1,RELN,PTHLH,ELOVL2,PTPN13,PTPRO,PTPRZ1,RAB3IL1,SH3TC2,RASGRF1,DBX2,FEZF2,HKR1,SLC6A15,PRIMA1,RNH1,UEVLD,AMER2,SALL1,LRFN5,SCP2,SUPT20H,HSPA4L,SCG5,SLITRK3,DZIP1,SLC1A6,FAM81A,SLC6A11,SLC8A3,TRIM67,ZNF667,OGDHL,SORCS3,PDZRN3,SOX3,SOX11,DOK5,LHFPL4,HECW1,PEG10,KIF1B,NPAS3,SSTR1,SYNE2,RHBDL3,TAC1,VWC2,SATB2,PCDHGC5,PCDHGB7,PCDHB15,PCDHB10,PCDHB6,THBS4,TJP1,TPM1,DOK6,RGMB,RUSC1,TSN,CA14,TUB,PRR18,TMEFF2,FLRT2,PLEKHH2,KCNK12,PCDH20,ZNF540,NDRG4,SPIRE1,ZNF225,CA10,RGMA,ADAMTS9,WNK3,WNK2,HRASLS,MSRB3,AP3B2" Coexpression M1884 Genes up-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-28 1.17E-24 6.87E-26 6.82E-25 354 1305 "DPF1,RALGAPA1,ABAT,KCNH8,ASIC2,ACHE,ADAR,ADCYAP1R1,SLC12A5,CDC7,UNC5A,ADORA3,ADRA1D,ADRB2,AGT,AK2,LRRC7,ALCAM,KCNT1,BEGAIN,BIN1,ANK3,APBA2,APBB1,KCNAB2,APC,GAS7,DGKZ,GPAM,AQP6,MADD,ARRB2,ASGR1,ASPH,ATP1A1,ATP1A3,ATP2B1,ATP2B2,ATP2B3,AZGP1,RGS9,FGF17,BMP7,CDK5R1,NAE1,C1QC,GPC2,BSN,CACNA1A,CACNA1D,DDR1,CACNB4,CACNG1,CALB2,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2G,CAPN3,RHBDL1,ISPD,CBS,CCK,MTMR7,INA,ENTPD2,CDK11B,CDC25B,KCNAB3,CDH8,DLGAP2,CDO1,DLGAP1,CHGB,CHN1,CHRM1,CHRM4,CHRNA4,RAB3C,CHRNB2,LHX2,DLGAP3,PPT2,SLC24A2,CLTA,RAB26,CNGA3,CNTN1,COL9A1,COX4I1,CRHBP,SH2B1,AKAP12,CRYBB1,FEZ1,NCAN,CTNND2,SIRPA,DBN1,SNAP91,SV2B,DLG2,GRIN3A,DPP6,DRD1,DYRK1A,DNM1L,ABCC9,WDPCP,EDN3,EDNRA,EEF1A2,HIPK3,APH1A,EGFR,ABI2,EGR3,PLEKHA1,ELAVL4,CALCRL,COQ7,ENPP6,ERBB2,ERBB4,EXTL2,ACSL4,EFEMP1,DLC1,OLFM1,POLR1B,FGF14,FGR,HPCAL4,FOXG1,CAP2,FOXM1,EVL,SYT3,DPYSL4,CAMKK2,ST6GALNAC3,CSPG5,NSG1,DLL3,B3GAT1,GABBR1,HRASLS5,GABRA3,GABRB3,GABRG1,GABRG2,CPLX2,GFAP,LYVE1,GJB1,GNAL,GNAS,ADAP1,GPR19,RAPGEF4,GRIA1,PLCD4,GRID1,GRIK1,GRIK4,GRIN1,GRIN2D,NR3C1,GRM1,GRM3,GRM5,GRM8,GSTT2,PADI2,FRMD5,ACOT7,SYNPO,HP,HTR2A,HTR5A,MYLK2,IGF1,IGFBP1,HES5,ITPKA,ITPKB,JAK2,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC2,KCND2,KCND3,KCNH2,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK3,KCNN3,KCNQ3,KHK,KIT,L1CAM,CAMK2N2,LSAMP,MAG,MAOB,MAP2,MAP6,MAPT,MAT2A,SYT9,SHC3,KITLG,AFDN,MOBP,PTOV1,MT3,SCG3,MXI1,MYH6,MYH7,MYL3,NAP1L1,NDUFA5,NEFH,NELL2,NF1,NOS1,NPY,NPPA,NPTX2,CLEC9A,NRCAM,NRGN,NTRK2,NTRK3,OXTR,PAK3,PDCD2,PDE2A,PDE3A,PDE4A,PDE4B,PDE4D,PDE1B,PDGFRA,PFKFB2,PFKFB3,PGAM2,PHKG1,NLGN3,NALCN,CAMKV,PIK3CD,FXYD1,EPN1,MTRF1L,TRHDE,EPB41L4B,SH3KBP1,POU3F2,PPARA,MINDY2,PPP1R1A,PRKCB,PRKCG,PRKCZ,MAPK3,PRPSAP2,MASP1,PSMA6,PTK2,PTPRE,PTPRH,PTPRN,PYGM,RAB3A,RALGDS,RET,RTN1,S100B,MAPK12,ATXN1,HOGA1,SCN3A,SCN7A,SELL,MRAS,KIF27,SCG5,PPP1R9A,SH3GL2,CNKSR2,BCAN,NLGN1,ST3GAL3,ST8SIA1,WDR37,SLC1A2,SLC4A3,SLC1A6,SLC6A7,SLC6A9,SLC6A11,SLC8A2,SLC8A3,ARFGAP1,RIMS1,SNAP25,SNCA,MYT1L,SOX10,DDN,SST,SSTR1,SSTR2,STX1A,GSE1,FGD4,ABCC8,ARC,SYN2,TAC1,TACR1,MCF2L,EXOC7,CNTN2,PCDHGA11,TF,TGFBR3,THBS4,CDH22,CBX5,TLR4,CABIN1,TNR,TRH,TST,TTPA,CADM1,UBE3A,UCHL1,VSNL1,SLC13A3,NDRG4,DOCK8" Coexpression 17880687-TableS3 Human Embryo_Heim07_1515genes GeneSigDB 7.26E-27 8.40E-23 4.67E-24 4.63E-23 279 971 "CSMD2,NDRG2,TMEM132B,AXIN2,NLGN4X,PCDH19,SPOP,MARCH4,SYT13,PDZD4,APBA2,APBB2,GAS7,ALS2,PHYHD1,VAT1L,SHROOM2,CDC14B,IGDCC4,DACT3,RASL11B,TMEM108,CADM3,KIF1A,ADAM23,NRP2,PROM1,SYNJ1,SGCE,CALB1,THSD7A,PTBP2,RUNX1T1,CLDN10,CCKBR,INA,MYOM2,DCLK1,LRRFIP1,CRLF1,CHN2,PLEKHB1,SLIT2,PPT2,TMEM59L,FAM189A2,TJP2,VAX2,ABCG2,DNAJB5,HOMER3,TMEM155,CNR1,AKAP7,COL9A3,C2CD2,RBM39,TENM4,FEZ1,SIPA1L1,CNTNAP2,CTH,HDAC9,TOX,MATR3,RIMS3,BRINP1,PITPNC1,MAGI2,LYPD1,GSDME,NTM,RABGAP1L,FAM107B,OLIG1,DYNC1I1,DPP6,DUSP9,DNM1L,ST8SIA3,EDN1,YAF2,FAM13A,EGFR,TMEM132E,EPB41,EPB41L1,EPB41L2,RASGRP2,ERBB2,EFS,TMEM74,RASL12,FABP7,TBC1D16,ACSL4,DLC1,OLFM1,AMOTL2,SEMA4D,FLNC,TACC2,B3GAT1,MPP6,MEGF10,GABBR1,GAD1,IQGAP2,CPLX2,IGSF5,GCNT2,PCDH17,GHR,RND1,GLI2,GLRB,TOX3,PCDH11X,KDM2B,GNAO1,GNG3,GNG4,LNX1,PRUNE2,GPM6B,MCHR1,DIDO1,RFFL,NR3C1,ATOH8,RASSF8,HAS2,TOX2,BACH2,IFI16,RBPJ,IL6ST,KCNJ4,KCNN2,KCNQ2,L1CAM,PAXBP1,SMAD9,AQP11,CHST6,SHC3,MEIS1,MEIS2,MID1,PPM1L,CD200,MPP2,TAGLN3,DDX25,RTL5,FXYD6,NASP,NCAM1,NEFH,NFIA,NODAL,SETD4,OGG1,PBX1,CDK18,PRTG,PDGFRA,ENPP2,SLC10A4,GNG2,SNX10,PLP1,ANKRD16,EPB41L4B,MINDY2,PPP1R1A,SLC22A23,SYTL2,PTPRG,PTPRO,PTPRZ1,ZSCAN2,TTC13,VEPH1,RET,RFX3,RGS3,PRIMA1,RIC8B,MRAP2,BAALC,RPS6KA2,LGR4,HUNK,RTKN,CLIP1,AMER2,MAPK12,SEMA6D,SATB1,PEAR1,ASRGL1,MRAS,RASA3,ANKRD6,SLC1A6,URGCP,PREX2,FAM214B,KANSL3,SEPHS1,SHANK2,SLC15A2,TET1,CPEB4,LIMCH1,SNRPN,PDZD2,SOX3,KIF21B,FNBP1,LHFPL4,SPP1,PEG10,ARHGAP26,SPTAN1,TSPYL2,LMO3,LRRC4,SEPT3,GSE1,KLHL7,FGD4,ZFR2,SYNE2,RHBDL3,VPS13A,KAZN,PDLIM2,CNTN2,KLHL4,WSCD1,TCF7,TCF12,AKNA,PCDHAC2,AHCYL2,TEK,LEFTY2,SLC44A1,TIAM1,TLL2,LRRC8A,FAM124A,TPM4,RGMB,TRH,TRIO,TRPS1,ZMYND8,FNDC5,RPRM,FLRT2,CCDC136,MICAL1,VSNL1,RBFOX3,CLIP2,SLC13A3,SF1,ZIC2,PLPP4,LRP8,SHD,TMEM178A,SCG2,RTN4,AP3B2,SPATA13" Coexpression M7617 Set 'Eed targets': genes identified by ChIP on chip as targets of the Polycomb protein EED [GeneID=8726] in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.61E-27 9.95E-23 5.24E-24 5.20E-23 298 1062 "TTYH1,FAM43B,ARID1A,CSMD3,ADARB2,DSCAML1,SLITRK1,ADCY8,CDC7,SORCS1,LRFN2,SLC24A4,KIAA1324,SORCS2,ARHGAP20,PCDH10,LRCH2,LCORL,LGR5,ZFYVE28,ARNTL,RGS20,ASCL1,BRINP2,CHRD,ASTN1,ATP1B3,NOL4,DOCK11,BMPR1B,CACNA1G,CDK5R2,MMD2,CACNA1B,CACNA1D,CACNA1E,HAP1,NGB,CAMK2B,CH25H,CBLN1,INA,NEURL1,DGKI,REPS2,DCLK1,NOG,CRLF1,CHN2,B4GALT6,SLIT2,LHX2,TMEM59L,VAX2,CNTFR,COL4A5,COL9A2,NRG2,CNRIP1,CRHBP,SLC32A1,GDA,RGS6,FEZ1,CSNK1E,PDE4DIP,CTNND2,FRMPD4,CENPL,DGKG,SCRN1,DCC,ZEB2,MAGI2,LYPD1,GSDME,SNAP91,SV2B,SPOCK3,DLX1,GRIN3A,OLIG1,EBF1,CNNM1,RASGRP1,EEF1D,EFNA3,YAF2,EGFR,EGR3,PLXNC1,TMEM132E,ELAVL2,EMX2,EN2,OLIG2,EPHA5,EPHB1,EPS8,ERBB4,NRN1,ABCA8,ZIC4,BAIAP2,HPCAL4,FOXG1,FOXF2,ZMYND15,PSD2,AFF2,TRMO,RASL10A,DACH2,TPPP3,TBR1,MEGF11,GABRA2,GABRA4,ILDR2,GAD1,GAD2,B4GALNT1,NKX6-2,GBX2,GFRA1,PCDH17,GHR,KIRREL3,NTNG2,MAP7D2,INSM2,PCSK1N,DCLK2,GPM6B,PRLHR,GPR12,STMN2,GRIA2,GRID1,GRIK1,GRIK3,GRM3,GRM7,PTPRT,BVES,SOX21,GUCY1A1,ATOH8,IRAK3,HBA1,IGSF21,FRMD3,BACH2,HLF,HPSE2,TLX1,HSPA1L,SHISA6,SCIN,BRINP3,LRRTM1,ITPKA,KCNA1,KCNC2,KCND3,KCNH1,KCNK2,KCNMA1,KCNQ3,CREG2,LMO1,C1orf194,MAPT,TM6SF1,MID1,MT1M,RSPO2,MDGA1,HS6ST3,LAYN,PABPC1L2A,HNRNPM,NCAM1,NEFM,NELL1,NEUROD1,NEUROD2,NFIX,NKX2-2,NPTX1,NPTX2,NRCAM,NTRK2,GPR88,PAX6,DPY19L2P2,PCDH8,PDGFRA,SLC10A4,PENK,TMOD2,ST8SIA5,PLEC,PMP22,TRHDE,EPB41L4B,POU3F2,POU3F4,PRKCB,MAPK4,DCHS2,RELN,CNNM2,SIDT1,PLPPR1,PTHLH,ELOVL2,EML5,SUSD4,RASGRF1,FEZF2,CRTAC1,RGS10,RIMKLA,STK32B,WLS,RYR3,SEMA6D,LRFN5,SCN4B,ELMOD1,GALNT10,PPM1E,FUZ,SHC4,SLITRK3,ST8SIA1,SLC1A2,ZNF365,FAM81A,SLC6A1,PKNOX2,SLC8A3,TRIM67,SLIT1,SORCS3,DMRTC1,PDZD2,SOX1,SOX3,SOX5,C11orf87,CLSTN2,COLGALT2,MESP1,SSTR1,SSTR2,NKAIN2,ABCC8,PLCB1,ASTN2,TAC1,ROBO3,TAL1,ADGRL3,CHST8,HHIP,HEY1,ICAM5,NR2E1,CSMD1,PARD3,DOK6,TRH,ANKRD20A2,TTPA,TMEFF2,AMOT,FLRT2,VGF,VIPR2,WNT7A,KCNK12,ZIC1,ZIC2,ZNF711,TRIM9,ZBTB16,LAMP5,UPF3A,SLC30A3,CA10,SLC30A4,NAV2,KCNAB1,JMJD1C,DPF3,ST8SIA2" Coexpression M16478 Genes down-regulated in medulloblastoma tumors from animals with inactivating mutations of one copy of PTCH1 or SUFU [GeneID=5727;51684] in conjunction with TP53 [GeneID=7157] loss. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.98E-26 2.29E-22 1.15E-23 1.14E-22 56 83 "C1QTNF4,CNIH2,PDXK,ASPH,ATP2A2,ATP2B2,KIF1A,CACNA1G,CA8,CALB1,CAMK2D,CBLN1,DCLK1,NRXN3,PREPL,SLC32A1,NRSN1,SPOCK2,NTM,SEZ6L2,RCAN2,CEND1,GAD1,CSDC2,PCSK1N,GRIA1,GRM3,GUCY1A1,ITPKA,KCND2,KCNK1,KIF5A,MAP4,NCAM1,NEFH,PENK,SKOR1,PRKCG,MASP1,RAB3A,MEG3,ELMOD1,SLC1A6,SLC8A1,NAPB,FNBP1,C11orf87,CLSTN2,SYT1,TRPC3,VSNL1,SLC13A3,ZIC3,NDRG4,LRP8,SLC4A10" Coexpression M1951 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.68E-26 3.10E-22 1.48E-23 1.47E-22 170 490 "ABR,ACHE,GPRIN1,ADRA1D,ADRA1B,ADRB2,SLC44A5,SNX32,HFM1,MARCH4,LTBP4,GOLGA7B,SYT13,DOC2A,ANK1,CNIH2,ARHGDIG,ATP1A3,ADAM23,TTC9B,BMP7,CACNA1G,BSN,CACNA1B,CALB2,SYT6,CH25H,BRSK2,MAP7,ARHGEF25,CBS,SHISA7,USP2,MTMR7,SYNGR3,NEURL1,CRLF1,CHGB,CHRNB2,ANKRD35,COL9A3,MFSD4A,SLC32A1,GDA,AATK,LRRC3B,PDE4DIP,PITPNM3,SPOCK2,BRINP1,DNAJC6,ZNF804A,C8orf34,PLPPR4,CCDC3,DNM1,DYNC1I1,DPP6,RASGRP1,EFNA2,ELAVL2,RCAN2,RCSD1,REEP2,OLFM1,FGF12,SEMA4D,FLNC,C2orf88,DPYSL4,AK8,FAM49B,GPR153,DLL3,HHIPL1,NRG3,GAD2,NKX6-2,SRRM4,ACSS1,STARD10,CPLX2,CYP46A1,MAP7D2,GNAL,GP1BB,DIPK1C,CCDC184,TMEM121B,GRIK2,GRIK4,GRIN2D,MFSD2A,SLC2A6,TNFAIP8L3,LRRC75A,IRF8,KIAA1755,INSM1,C2CD4C,ITPKA,KCNB1,KCNF1,KCNJ10,KCNK2,CREG2,SMAD9,PIK3AP1,MATK,MBP,ADAM11,TM6SF1,SRSF12,MN1,NNAT,NPY,NPR2,NPTX2,KCTD15,NECAB2,PACSIN1,FA2H,DIRAS2,SIDT1,PTHLH,ELOVL2,PTPRB,PTPRE,RAP1GAP,ZMAT4,DUSP15,RFX2,PRIMA1,LGI2,RAVER2,SNX22,RIMKLA,PTGR2,RTN1,PEAR1,KIF16B,ABLIM3,SLC4A3,SLC1A6,RADIL,SLC8A3,TMEM132D,RIMS1,SNCB,LHFPL4,EPB41L3,FCHO1,ARC,SLC37A2,POPDC3,TCF7,TMEM151B,NSD1,SLC44A1,TLL2,TPM1,KCNE5,LRTM2,OSBP2,MGAT5B,VIPR2,CELF4,PLPPR5,SYNC,PRDM8" Coexpression M4500 Genes down-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.90E-26 1.03E-21 4.68E-23 4.65E-22 251 854 "KIDINS220,OSBPL8,SPOP,ALCAM,BCAR3,MRTFA,AMPH,OGT,CDC42BPA,PPFIA1,PKP4,PARG,APBB2,APC,APP,CASK,RGS20,CDK13,NCOA1,NUMB,EIF4G3,ATP2B1,BARD1,BLM,DST,ST3GAL5,SYNJ2,ARHGEF7,FUBP1,MTMR3,WASF1,BTRC,SPAG9,KRIT1,USP6,CDC27,CDH2,ZMYM4,LRRFIP1,FOXN3,SOCS6,SLIT2,ZFYVE9,NMT2,TJP2,QKI,NIPBL,SLC4A7,AHCTF1,NECTIN3,CLOCK,C2CD2,RBM39,CREB5,NCOR2,LRIG1,ARHGEF10,MICAL2,SIPA1L1,SOCS5,FAM169A,PHF14,PUM1,DOCK4,GAPVD1,HDAC4,ZFYVE16,DAPK1,CTIF,ZNF804A,ZEB2,CEP170,SACS,RABGAP1L,ARNT2,DMD,ABI1,GNE,MAMLD1,DNAJB6,DYRK1A,E2F5,TSPAN5,YAF2,EGFR,VPS13B,EPS8,F3,ACSL4,TAOK3,DLC1,SEC24B,KIAA1109,SUCO,CAP2,FOXO3,PDLIM5,ATP6V1H,ATP2C1,STAU2,MPP6,FYN,STAG2,ZMYND11,NCKAP1,SEPT9,WASF3,AHDC1,MALT1,DBF4,GLRB,ZNF638,FERMT2,ADGRA3,NR3C1,MAP4K5,ARHGAP19,AGFG1,RBPJ,KIF2A,KIF5C,KLC1,ARHGAP12,MARK3,MBNL1,MEIS2,MIA2,MID1,MITF,MKLN1,AFF1,MN1,MTR,NEK1,CNOT4,SLC11A2,DDR2,OPA1,PCMT1,PIK3C2A,CCSER2,FTO,STRN3,SCHIP1,MED1,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,PRKACB,PKN2,MAPK8,ELOVL2,PTK2,PTPN13,PTX3,ARID4A,RDX,REV3L,RGS7,ZC3H14,RPS6KA2,CLIP1,ATXN1,ATXN2,SEC14L1,SUPT20H,SCAF8,ITSN1,CHD9,FNDC3A,R3HDM2,WDR37,ABLIM3,RAB3GAP1,SLC20A2,LIMCH1,TMCC1,SON,DOK5,KDM3A,ZHX3,MYCBP2,KDM4C,ERC1,CDK19,SPART,SRPK2,TAB2,CLASP2,LARP4,ST5,NEK4,RGL1,GSE1,FAM168A,ZC3H4,PRRC2C,SYNE2,VPS13A,ANKRD28,KAZN,MTCL1,DNMBP,CAMSAP2,FAM208A,WWC1,FBXW11,TBL1X,EHBP1,DMXL2,SATB2,TCF7L2,ZEB1,TRIM2,TCF12,WASHC4,CLASP1,WDR7,DOCK9,PSD3,PUM2,FRYL,SIK3,DICER1,TGFBR3,TIAM1,R3HDM1,PARD3,KAT6B,TP53BP1,TP53BP2,RBFOX2,TRIO,TRPC1,ZMYND8,SSBP2,HIRA,FAM155A,UBE3A,FLRT2,VLDLR,WRN,XPO1,XRCC4,INTS3,EVI5,NAV3,KAT6A,CERS6,FXR1" Coexpression M2817 Genes up-regulated in prefrontal cortex (PFC) of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.32E-25 1.53E-21 6.65E-23 6.61E-22 92 195 "RALGAPA1,ACTN1,GPRIN1,PCDH19,BIN1,OGT,DGKD,ATP1A3,SLC4A4,ATP2B1,CDK5R1,BSN,CAMK2A,ZNF445,DLGAP2,NUMBL,SRSF11,CPNE6,NRXN3,CNR1,RBM39,TCAF1,KIAA0513,SPOCK2,ZNF804A,ZEB2,ZC3H11A,DDX46,POM121,SMG7,NTM,DLG4,CD99L2,DNM2,CPEB2,CNNM1,PLXNC1,SRRM1,DNAJC27,PTK2B,ATP8A1,PPP1R1B,OLFM1,B3GAT1,DOT1L,ILDR2,CPLX2,PRRC2B,GRIA1,RNF165,LINGO1,CREG2,KIF5C,MEF2C,NFIX,OPCML,PBX1,TMOD2,PFKP,PIK3R1,SLC25A23,TNPO2,PPP2R2C,PPP2R5E,PRKAB2,PRKCG,PYGM,MEG3,LINC00461,TNFRSF19,FNDC3A,SLC1A2,SLC1A3,SLC6A1,SLC8A1,SMARCC2,SP4,MYCBP2,NCDN,SYN2,TCF4,TRIM2,GPRIN3,NACC2,RIMBP2,R3HDM1,NR2C2,UBTF,RICTOR,PLPPR5,WNK1,SLC17A7" Coexpression M2808 Genes up-regulated in neurons. MSigDB C6: Oncogenic Signatures (v6.0) 3.51E-24 4.06E-20 1.69E-21 1.68E-20 60 100 "SYT13,PPFIA2,AMER3,CPNE5,CALB1,CAMK2B,CCK,CRHBP,GDA,KIAA0319,SV2B,HS3ST2,CALN1,DYNC1I1,DRD1,ENO2,DMTN,CACNG3,RASL10A,TBR1,GABRA5,GABRG2,GAD2,JPH4,GPR22,NXPH2,HPCA,SLC6A17,ITPKA,MEF2C,MYH3,NEFM,NELL1,NRGN,HCN1,PENK,CAMKV,TRHDE,SIDT1,RGS4,SLC6A7,SLC8A1,NAPB,MYT1L,CLSTN2,SST,STX1A,STXBP1,SYT1,SYT4,SYT5,SATB2,PHF24,ICAM5,CELF4,LAMP5,PRDM8,SCG2,SLC17A6,CPNE4" Coexpression 18308945-Table3 Human StemCell_Huang08_60genes_NSCs GeneSigDB 5.30E-24 6.13E-20 2.45E-21 2.44E-20 41 52 "SPARCL1,ANK2,AQP4,ASCL1,ATP1A2,DCLK1,NRXN1,LRRC3B,NCAN,CTNND2,EDNRB,ETV1,FABP7,FOXG1,CSPG5,MEGF10,GAD1,GAP43,DNER,GPM6A,GPM6B,GRIA2,FAM107A,TUBB2B,MAP2,PAX6,SLC10A4,FAT3,PTN,PTPRZ1,RFX4,AMER2,SALL1,SEMA6D,ARX,SLC1A2,SLC1A3,SOX2,SOX11,COLGALT2,ZIC1" Coexpression 17880687-TableS1 Human Embryo_Heim07_1650genes GeneSigDB 2.64E-23 3.05E-19 1.17E-20 1.17E-19 300 1122 "ABHD6,CSMD2,NDRG2,FMNL2,TMEM132B,ADCYAP1R1,OLMALINC,NLGN4X,ZNF608,PCDH19,TAOK1,SPARCL1,SPOP,PDZD4,APBB2,GAS7,VAT1L,DACT3,DDX3Y,EIF4G3,CADM3,KIF1A,BACH1,SYNJ1,ARHGEF7,CASTOR3,SGCE,CA8,CACNA2D1,THSD7A,PTBP2,CANX,RUNX1T1,CBLN1,CLDN10,CCKBR,INA,SCARB1,SEPT7,CDC42,DCLK1,CRLF1,CHN2,PLEKHB1,B4GALT6,SLIT2,KMT2C,NRXN3,TMEM59L,FAM189A2,ABCG2,HECTD1,NIPBL,HOMER3,TMEM155,CNR1,AKAP7,COL9A3,SLC4A7,AHCTF1,RTTN,BAG4,FAM171B,C2CD2,TENM4,FEZ1,SIPA1L1,PDE4DIP,CNTNAP2,FAM169A,HDAC9,TOX,TBC1D5,MATR3,DAPK1,BRINP1,YTHDC1,ZEB2,MAGI2,FBXO25,LYPD1,SMG7,G3BP2,RABGAP1L,FAM107B,USP3,DYNC1I1,NR1D2,DPP6,DUSP9,EDN1,FEM1B,FCF1,KLHL5,YAF2,FAM13A,PHF20L1,EGFR,RGS17,OLIG2,EPB41,EPB41L2,LRRC23,ERBB2,RTN3,FABP7,SH3YL1,TBC1D16,ACSL4,DLC1,OLFM1,FHL1,POLK,FLNC,DPYSL4,TACC2,SORBS1,UFM1,GABBR1,GAD1,AHCYL1,GCNT2,ARFIP1,PCDH17,GHR,RND1,GLI2,GLS,TOX3,TNRC6A,ZNF638,HTATSF1,GNAS,GNG4,GPD2,PRUNE2,GPM6B,STON1,LPAR4,MCHR1,EML4,DIDO1,NR3C1,KIF3A,ATOH8,RASSF8,HAS2,UBE2QL1,TOX2,BACH2,MIER3,HNMT,IFI16,RBPJ,IL6ST,ZNF678,KCNJ4,KCNN2,CAMK2N2,PAXBP1,SMAD9,MAP2,AQP11,MBNL1,CHST6,TM6SF1,MEIS1,MEIS2,MID1,MITF,CD200,MPP2,TAGLN3,DDX25,RTL5,FXYD6,NASP,NCAM1,NEFH,CCDC13,NFIA,CNOT4,SLC11A2,PBX1,PRTG,PDGFRA,ENPP2,GNG2,PIK3C2A,ZNF655,PLP1,PLXNB1,PMP22,MINDY2,PPP1R1A,CRLS1,KANSL1,CEP41,PRODH,SLC22A23,SYTL2,PTPRG,PTPRZ1,PEX5,ZSCAN2,TTC13,USP47,VEPH1,RET,FIGN,RFX3,RGS4,RIC8B,RPRD1A,EXD2,BAALC,SPIN3,HUNK,RTKN,CLIP1,RYR3,AP1AR,AMER2,MAPK12,SEMA6D,ATXN2,FNIP1,PEAR1,ASRGL1,MRAS,TRA2B,FERMT1,CNKSR2,ANKRD6,SLC1A6,URGCP,PREX2,KANSL3,CCDC88A,SHANK2,SLC15A2,CPEB4,GKAP1,LIMCH1,PALLD,FAM126B,SOX3,FNBP1,SOX11,LHFPL4,PEG10,TSPYL2,RBM26,LMO3,LRRC4,SOX21-AS1,SEPT8,SEPT3,FGD4,PRRC2C,TMEM150C,KAZN,FBXW11,KLHL4,WSCD1,TCF7,AHCYL2,LEFTY2,ZMAT3,SLC44A1,TIAM1,LRRC8A,TP53BP1,SEZ6L,TPD52,TPM4,RGMB,TRH,TRPS1,FNDC5,RPRM,FLRT2,VSNL1,RBFOX3,WIPF1,SLC13A3,SF1,ZIC2,KCNT2,PLPP4,WNK1,MAP3K12,SHD,STOX2,TMEM178A,NAV2,RTN4,UBE3B,JMJD1C,NHSL1" Coexpression M2105 Genes whose expression was significantly and positively correlated with the number of perineuronal oligodendrocytes in the layer III of BA9 brain region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.83E-22 2.11E-18 7.82E-20 7.77E-19 221 756 "ASIC2,RBM10,ADAR,AMPD2,BIN1,PPFIA4,APBA2,APLP1,DGKZ,SHROOM2,MADD,ARRB2,MTMR9,ADGRB2,ST3GAL5,BSN,BAIAP3,CAMK2B,CAMK2G,CANX,CCK,INA,SYNGR3,ENTPD6,CD81,DCLK1,CDH18,MYL6B,STOML1,CLTA,CLTB,FADS2,TMEM184B,SULT4A1,CABP1,MAGED1,COX4I1,MYRIP,CRMP1,CRY2,CRYM,FEZ1,MICAL2,ATRNL1,IPCEF1,NCAN,SLITRK5,PPP1R16B,CX3CR1,SEC14L5,DOCK4,KIAA0513,RASSF2,RIMS3,SPOCK2,IP6K1,DBN1,ELMO1,RUSC2,COPS7A,SNAP91,SV2A,ARNT2,KBTBD11,DNM1,DPYSL2,SEZ6L2,EFNB3,EGR3,LINC00599,EIF4G2,ENO2,RCAN2,DMTN,NCALD,ECSIT,CACNG3,TUBB3,TUBB4A,CORO2B,RACK1,CHST15,OLFM1,ACTL6B,UBE2E3,FOXG1,C1orf61,DCTN2,STAMBP,RASL10A,ARFGAP2,NSG2,B3GAT1,GABBR1,CHL1,GABRB1,GAD1,NCKAP1,GPR162,GFAP,RUNDC3A,RNPS1,GLRB,GLS,OS9,RAB40B,GNAS,PRRC2B,STMN2,PADI2,ACOT7,GABARAPL2,HMGCR,HPCA,MSL1,IDH3B,ITPKA,KCNF1,KCNK1,KCNN1,MAN2A2,MOG,CD200,PTOV1,LYRM9,FXYD7,NBL1,NEFH,NELL1,NNAT,NPY,NPTX1,NRDC,NRGN,NUCB1,OMG,DPY19L2P2,PCSK1,PDE2A,ENPP2,PFKP,CDK14,SERPINI1,FTO,FXYD1,PLP1,NECAB2,PTPA,MAPK3,KLK6,NDUFS7,PSMA6,PTPRN,PTPRN2,IQSEC3,ZMAT4,DPF2,RGS7,RNH1,RTN1,S100B,SARS,TRA2B,PUF60,SCG5,FAM102A,CCDC92,CLSTN1,ZNF365,SLC4A3,BTBD3,DHX30,WDR47,SMARCA4,SMARCD3,SNCB,FAIM2,KIF21B,NMNAT2,SPTAN1,RAP1GAP2,CLASP2,SST,EPB41L3,NCDN,SEPT8,STX1A,STXBP1,SYT11,SYN1,SYP,COBL,TAC1,DDHD2,TAF6,MCF2L,KIAA1107,MGRN1,WDR7,PHF24,TMEM151B,PUM2,BEX4,RIMBP2,CABIN1,WBP2,RUSC1,TUBB2A,UCHL1,CLDND1,ATP6V0E2,SPHK2,REEP1,LMAN2L,RNF103,TUBA1A,SCG2,WIPF2,NELFE,CAMK1G,AP3B2" Coexpression M8448 Set 'PRC2 targets': Polycomb Repression Complex 2 (PRC) targets; identified by ChIP on chip on human embryonic stem cells as genes that: posess the trimethylated H3K27 mark in their promoters and are bound by SUZ12 [GeneID=23512] and EED [GeneID=8726] Polycomb proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.45E-22 2.84E-18 1.01E-19 1.01E-18 198 652 "TTYH1,FAM43B,CSMD3,ADARB2,DSCAML1,SLITRK1,ADCY8,SORCS1,SLC24A4,KIAA1324,ARHGAP20,LRCH2,LGR5,ZFYVE28,RGS20,ASCL1,BRINP2,CHRD,ASTN1,NOL4,CACNA1G,CDK5R2,CACNA1B,CACNA1D,CACNA1E,CH25H,CBLN1,INA,DGKI,REPS2,CRLF1,SLIT2,LHX2,TMEM59L,VAX2,CNTFR,COL4A5,COL9A2,NRG2,CNRIP1,SLC32A1,FEZ1,PDE4DIP,CTNND2,FRMPD4,DGKG,DCC,ZEB2,SV2B,SPOCK3,DLX1,GRIN3A,CNNM1,EFNA3,EGR3,TMEM132E,EN2,OLIG2,EPHA5,EPHB1,ERBB4,ZIC4,HPCAL4,FOXG1,ZMYND15,RASL10A,DACH2,TPPP3,TBR1,GABRA2,GABRA4,ILDR2,GAD2,B4GALNT1,NKX6-2,GBX2,PCDH17,GHR,KIRREL3,NTNG2,INSM2,DCLK2,GPM6B,PRLHR,GPR12,STMN2,GRIA2,GRID1,GRIK1,GRIK3,GRM7,PTPRT,GUCY1A1,ATOH8,HBA1,IGSF21,FRMD3,HPSE2,TLX1,SHISA6,BRINP3,LRRTM1,ITPKA,KCNA1,KCNC2,KCND3,KCNH1,KCNK2,KCNMA1,KCNQ3,C1orf194,MAPT,MT1M,RSPO2,HS6ST3,LAYN,PABPC1L2A,NCAM1,NEFM,NELL1,NEUROD1,NEUROD2,NFIX,NKX2-2,NPTX1,NTRK2,GPR88,PAX6,DPY19L2P2,PCDH8,PDGFRA,SLC10A4,PENK,TMOD2,PLEC,PMP22,POU3F4,MAPK4,DCHS2,SIDT1,PLPPR1,PTHLH,SUSD4,RASGRF1,FEZF2,CRTAC1,RGS10,RIMKLA,STK32B,RYR3,SEMA6D,LRFN5,SCN4B,ELMOD1,PPM1E,SHC4,SLITRK3,SLC1A2,FAM81A,SLC6A1,PKNOX2,TRIM67,SLIT1,SORCS3,PDZD2,CLSTN2,COLGALT2,MESP1,SSTR1,SSTR2,ABCC8,ASTN2,ROBO3,TAL1,ADGRL3,CHST8,HHIP,HEY1,ICAM5,CSMD1,DOK6,TRH,ANKRD20A2,TMEFF2,FLRT2,WNT7A,KCNK12,ZIC1,TRIM9,ZBTB16,LAMP5,SLC30A3,CA10,SLC30A4,NAV2,KCNAB1,DPF3,ST8SIA2" Coexpression M1941 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation at K4 (H3K4me2) and trimethylation at K27 (H3K27me3) in brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.76E-22 3.20E-18 1.10E-19 1.09E-18 286 1069 "CPNE2,ABAT,KCNH8,ASIC2,NDRG2,ADORA2A,ADRA1D,ADRA1B,ADRB2,SLC24A4,SLC44A5,MTUS1,SORCS2,C1QTNF4,BCAR3,SYT13,DPP10,VAT1L,CPNE5,LGR5,SFMBT2,ASCL1,PTCH2,CHRD,TMEM108,SLC4A4,ADGRB2,PROM1,BMP7,CA4,CABP7,SYT6,CH25H,CBLN1,CBS,CCKBR,INA,SYNGR3,ENTPD2,L3MBTL4,NOG,CACNA2D2,CHRNB2,LHX2,IGDCC3,HS3ST5,SEC31B,SLC32A1,C1QL2,SNCAIP,TENM4,RGS6,PLXNA4,AIF1L,ZNF804A,CNIH3,LYPD1,CCDC3,DLX1,OLIG1,HS3ST2,SLC29A4,DPP6,EBF1,EDN3,CNNM1,HEYL,EGFR,EGR3,EMX2,EN2,OLIG2,EPB41L1,ERBB2,RCSD1,ADGRV1,EYA1,F3,DLC1,PPP1R1B,FGF11,SPSB4,FGFR3,SCARA3,FOXF2,FLT1,PDLIM5,DLL3,TBR1,NRG3,MEGF11,GAB1,GAD1,GAD2,NKX6-2,GALR1,SALL3,DISC1,GFRA1,PCDH17,C1QL1,GLDC,GLI2,GNAL,GNAS,DIPK1C,PRLHR,GPR26,TUBA1C,GRIK3,ADAMTS8,GRIN2C,GRM8,FAM19A2,PTPN5,BVES,MFSD2A,SOX21,ATOH8,WIF1,IRAK3,IGSF21,NXPH3,HRH3,TNFAIP8L3,SHISA6,IRF8,SOWAHA,ZIC5,PLD5,SCIN,SLC6A17,TUBB2B,ITGA7,C2CD4C,ITPKA,ITPKB,KCNF1,KCNH1,KCNH2,KCNJ4,KCNJ10,KCNQ2,KIT,LMO1,PIK3AP1,KITLG,PPM1L,CPNE9,RSPO2,MDGA1,MYCN,FXYD6,NBL1,NEFH,NELL1,NEUROD1,NEUROD2,NFE2L2,NFIX,NKX2-2,NODAL,NPTX2,HCN1,GPR88,CLDN11,OXTR,P2RY1,PAX6,PCDH8,CDK18,PDE3A,PDE4A,PDE1B,PDGFRA,PENK,SERPINE2,SEMA5B,ANLN,PLTP,PMP22,TRHDE,POU3F2,IRX1,PPARA,VSTM2L,PRKCZ,DIRAS2,PRODH,PROX1,RELN,LAMA1,SIDT1,PTHLH,STK32A,PTPRB,PTPRO,FAT4,RASGRF1,RASGRF2,DBX2,FEZF2,CRTAC1,RET,FIGN,RGS10,RNF220,SNX22,GLDN,PRR5L,SALL1,MAPK12,SATB1,SCN4B,SLC30A10,IL17RB,PEAR1,ARX,ASAP3,SHC4,BCAN,ABLIM3,SLC1A3,SLC6A1,SLC6A11,SLC12A4,EFHD1,MAST1,INAVA,PDZRN3,MYO16,SOX1,SOX2,SOX3,UNC5B,RAP1GAP2,SMOC1,SSTR1,ERBIN,STAC2,KANK1,SULF2,ADAMTS17,POPDC3,PDLIM2,CNTN2,TBX15,VWC2,SATB2,TCF7L2,TMEM151B,RALYL,CHST8,HHIP,CDH22,ICAM5,TLL2,NR2E1,PIK3R5,SEZ6L,TPM1,NTSR2,ANO5,RPRM,FAM181B,MGAT5B,VAV2,VGF,VIPR2,WNT7A,SLC13A3,KCNK12,ZIC1,ZIC2,ZIC3,ELFN1,PLPP4,DPYSL5,SLC30A3,CA10,PRDM8,TMEM163,RGS7BP,DOCK8,CBLN2,ST8SIA2" Coexpression M15472 Down-regulated genes distinguishing between early gastric cancer (EGC) and normal tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.60E-22 7.64E-18 2.55E-19 2.53E-18 131 366 "ABAT,ADRB2,NME5,KIAA1324,SRPX,AQP4,ASPA,ATP1A2,BCHE,BMPR1B,VSTM2A,CLDN10,INA,LONRF2,CCPG1,CFL2,CHGA,CHGB,JAM2,SLIT2,CLU,CNTN1,TCEAL2,MYRIP,MFSD4A,PLCXD3,ARHGAP24,RIMS3,ARMCX2,DNAJC6,MAGI2,CHRDL1,DMD,ARRDC4,DTNA,DTNB,EBF1,SIDT2,RCAN2,LRRC17,KCNMB2,RAB9B,CEP85L,ARMCX1,ABCA8,EFEMP1,ST3GAL6,FHL1,FUT9,GABRB3,DNER,GCNT2,ADAM28,GHR,LYVE1,GLUL,MAP7D2,GNAO1,GPM6B,GPER1,NR3C1,FAM107A,WIF1,UBE2QL1,PTGDR2,HLF,USP51,LINC00667,IL6R,ZNF385B,KCNJ16,KIF5C,KIT,LAMA2,LIFR,GPR155,ZNF667-AS1,MT1M,MTTP,LINC00672,NEXMIF,BEX5,NAP1L2,NCAM1,ALDH1L2,SMIM11A,NTRK3,PCDH9,ENPP2,SERPINI1,PLIN1,PLP1,SLC36A4,PRKACB,PTPRZ1,ZNF844,PID1,SUSD4,BEND5,VEPH1,FIGN,RGS4,PRIMA1,TTLL7,TMEM100,SCN7A,SOX6,SH3GL2,SLC1A2,SNRPN,SOX2,BEX1,SPART,PBLD,SST,SSTR1,ERBIN,SYT4,SEMA4A,UNC5D,ADGRL3,TPCN2,HHIP,RGMB,SYNPO2,TMEFF2,VLDLR,CLDND1,ETNPPL,PCDH20,STOX2" Coexpression M4391 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of TP53 [GeneID=7157] off adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.10E-21 2.43E-17 7.85E-19 7.80E-18 304 1172 "ABR,ABHD6,EMILIN3,FAM43B,SLC25A25,ELFN2,ADCY6,ADCYAP1R1,HHATL,GRAMD1B,KIAA1211,ADRB2,SNX32,TBC1D14,KIAA1324,C1QTNF1,USP35,CARNS1,GOLGA7B,ANK1,ANK3,APAF1,DGKZ,TNRC6C,SHROOM2,ZFYVE28,ARRB1,ASCL1,MARCH3,ASPA,MARK4,ALDH4A1,ATP2B2,ALDH7A1,ADAM23,BID,CFLAR,KSR1,BMP7,MYRF,BAIAP3,LDLRAD4,CACNB2,CABP7,KALRN,CAMK2B,CAMK2G,CAPN3,CAST,HIP1R,USP6,CBFA2T2,ENTPD2,DCLK1,CACNA2D2,ADGRG1,CLCN4,ABCG2,CNGA3,TMEM155,ARHGEF6,AKAP7,FAM149A,WHRN,COL9A3,NRG2,ZNF385A,SLC32A1,ABCG1,SUSD5,VCAN,CST3,UBXN2A,GREB1,ARHGEF4,GPSM1,USP6NL,SEC14L5,DOCK4,TOX,KIF26A,MAML1,BRINP1,DNAJC6,KLHL3,FBXO25,TMCC2,WDR20,CCDC3,ARNT2,ABCC5,USH1C,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,TMEM35A,EML1,EMX2,EN2,ENO2,VPS13B,EPB41,DMTN,MTSS1L,CEP85L,CDHR1,APC2,ADGRV1,F8,FAM198B,CHST15,STRADA,FECH,FGF1,FGF11,FGF13,FGFR3,BAIAP2,MEX3B,FOXF2,AGAP3,SEMA4D,FLNC,C2orf88,DPYSL4,TMEM107,HVCN1,ATP6V1H,NSG1,OGA,FYN,MEGF11,MEGF10,GAA,GAB1,GABRA4,ILDR2,GAD1,ZNF234,C15orf41,SEPT9,GATM,ALDH1L1,GCNT2,GDF9,AHDC1,CSDC2,GHR,GLDC,KDM2B,MAP7D2,INSM2,GNAS,GPT2,PRRC2B,MCHR1,GPR37,CROCCP2,DIDO1,GRIK3,GRM8,GSTT2,BVES,UBE2QL1,TOX2,FRMD5,FRMD3,ARHGAP19,INSYN1,HSD17B1,LINC00667,SHISAL1,KNDC1,DISP2,INPP5B,LRRTM1,ITGAM,ITPKB,KCNB1,KCNK3,CYP27C1,TTYH2,INSYN2,LIFR,PAXBP1,FGFBP3,ASPRV1,SMAD9,GPR155,MAP6,MBNL1,LOC643201,AFF1,MN1,NRBP2,MX1,MXI1,MYO6,MYT1,KCNK10,TREM2,DPY19L2P2,GNG2,ABCB1,ZNF655,RETREG1,CDIP1,EPB41L4B,FA2H,FITM2,VPS13C,SLC22A23,SIDT1,PTAFR,PLPPR1,FAM184A,MSANTD2,ZYG11B,ALG9,PCMTD2,GLDN,PRR5L,MAP6D1,CNTNAP3,MEG3,HUNK,KCNIP3,FAM182A,DRAXIN,HOGA1,HES6,ELMOD1,SLC30A10,PEAR1,SOX6,GALNT10,FAM102A,ARX,KIF16B,DZIP1,NBPF1,WDR47,ARHGEF40,ELMO2,INAVA,SNRPN,KDM4B,DOP1A,ZCCHC24,UNC5B,KIF1B,ZBTB43,EPB41L3,DIP2A,GSE1,ACSBG1,MLC1,FGD4,ARC,C12orf76,KAZN,MTCL1,CAMTA1,MCF2L,EXOC7,CNTN2,TBCEL,ANO4,ZFP90,TRIM2,DOCK9,SLC35G2,VWCE,ZMAT3,AKTIP,RIMBP2,TNS1,TSC2,TUB,HEPACAM,CADM1,VSNL1,TSPAN11,LAT2,WNT7A,ZIC2,ZNF708,USP32P2,ATP6V0E2,LYPD6,REEP1,EML6,ZNF195,CA10,GDPD5,STOX2,FAM13C,DOCK8,MARCH8,ZNF248,ZNF30,JPH3" Coexpression M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.07E-21 5.86E-17 1.83E-18 1.82E-17 144 428 "EMILIN3,GALNT16,SLITRK1,KIAA1211,LRFN2,NR0B1,SPARCL1,PCDH10,SYT13,AMPH,DPP10,PKP4,FAM131A,CACHD1,PDXK,IGDCC4,ATP2B1,ADAM23,ADGRB2,NRP2,C1QC,CACNA1G,WASF1,RUNX1T1,LDB2,CBFA2T2,CDH2,CDH10,LARGE1,MS4A7,CHRNA4,SLIT2,CNTN1,AKAP5,ZNF521,FAM171B,ENTPD4,CREB5,NCOR2,PDE4DIP,DOCK4,GPRASP1,HDAC4,RASSF2,DCC,ARMCX2,TIAM2,FAM107B,GRIN3A,CALN1,ABCC9,EDIL3,EDNRA,FEM1B,FAM13A,ABI2,TMEM132E,ELN,C8orf37,EPHA5,EPHB1,TMEM132C,MEX3B,NBEA,CAMKK2,DACH2,ADGRA1,ABLIM2,GABRA1,GABRA4,GABRB1,DENND2A,GAD2,AHDC1,GPM6B,GRIA1,ADAMTS8,GUCY1A1,GUCY1B1,MAP4K5,KLF12,NEGR1,IGF1,RBPJ,KNDC1,KCNA4,PACRG,MARK1,MATN2,MBD1,IL17D,MEIS1,MMP16,SAMD5,CCDC80,RSPO2,MYCN,NFIX,NTRK2,DDR2,PRTG,PDE1A,PDE1B,ENPP2,SEMA5B,CAMKV,PCDH18,CDIP1,PRRX1,SH3KBP1,PRKCB,PROX1,GON4L,PTHLH,RALGDS,DBX2,ZMAT4,REV3L,ROBO2,PRR5L,RIMKLA,HUNK,LRFN5,NTNG1,ANKRD6,SLC1A3,SLC1A6,SLC14A1,PALLD,ERC1,LHPP,LMO3,RHBDL3,KAZN,ADGRL3,TCF4,SYNPO2,TSN,FAM181B,WNT7A,PCDH20,PMEPA1,KCNAB1,NETO1" Coexpression M12135 Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.28E-21 9.58E-17 2.90E-18 2.89E-17 76 164 "TTYH1,ABCD2,CADPS,ASCL1,RNF182,NOL4,CDK5R1,BRSK2,INA,CFL2,ADGRG1,JAM2,LY86,CNR1,CSF1R,NCAN,UBXN2A,PNPLA8,ST18,CX3CR1,KIAA0408,HDAC9,TCAF1,SCRN1,BRINP1,JAKMIP2,EDNRB,ELAVL2,ELAVL3,ELAVL4,APC2,FABP7,SCARA3,FOXG1,NSG1,TBR1,FYN,ZMAT1,ACSS1,KIAA1841,GFRA1,GPM6B,NUDT21,STMN2,FRMD5,IGFBPL1,MAP2,MDM4,SCG3,RSPO2,MYT1,NAP1L2,NEUROD1,PDGFRA,SPATA6,POU3F4,PKIA,SKOR1,MAPK10,RGS4,RNH1,ATAT1,RTN1,SATB1,LINC00461,SCG5,KIF21A,SYT11,FGD4,RHBDL3,TAL1,PRMT8,SGK3,FMN2,FSTL5,SLC17A6" Coexpression M9112 Age down-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.89E-20 3.35E-16 9.84E-18 9.78E-17 72 153 "OGT,ANK2,EP400,ATP2A2,ATP2B2,ATP6V1G2,CDK5R1,CA4,CACNB2,CALB1,CALB2,CALM1,CAMK2A,CCKBR,CHGB,NRXN1,CLTB,CNTN1,NECTIN3,FRMPD4,DYNC1I1,NR1D2,DNM1L,MBNL2,ABI2,ELAVL2,ATP8A1,FGF12,FGF13,FOXG1,CAP2,ATP6V1H,NSG1,GABRB3,GAD1,GFRA2,NUDT21,TPPP,GRIA1,HTR2A,ITPKA,KCNJ9,MAP2,MAPT,MAT2A,MEF2C,TAGLN3,PCMT1,PDE4D,PENK,PRKCB,PRKCG,PRKCZ,MAPK9,PTPRO,RAB3A,PLEKHB2,RASGRF1,RGS4,SARS,SCN2B,SFPQ,PPM1E,KIF1B,TSPYL2,SST,VAMP1,SYN2,CDH22,CBX5,PITPNB,SLC17A7" Coexpression 19658189-TableS3 Human EmbryonicStemCell_Xu09_1311genes GeneSigDB 3.45E-20 3.99E-16 1.14E-17 1.13E-16 259 969 "ABAT,DGCR6,ACTN2,NDRG2,ADCY5,ADCY6,SORCS1,ADORA1,RNF150,ADRB2,MTUS1,GPR158,KLHL13,AGT,NME5,ANK2,PPFIA4,ANXA7,CPNE5,CDK10,PLA2G4C,CADPS,MARK4,ASPH,ATP1A1,SLC4A4,ATP2A2,ATP2B1,SLC2A11,ATP6V1G2,MYOM1,ADGRB2,RGS9,GPR146,BMP7,SYNJ1,JAZF1,CACNA1G,CACNB2,KALRN,CAMK2A,CAMK2B,CAMK2D,CAPN3,CAST,USP2,RGN,ENTPD2,DGKI,MYOM2,CDH2,CDH10,L3MBTL4,MAGI1,NRXN1,QKI,AKAP6,COL9A1,PNKD,CRHBP,CRY2,RNF14,MICAL2,CSNK1E,PHACTR3,HDAC9,ARHGAP24,ZFYVE16,HEPH,KIAA0319,KLHL3,SNAP91,DMD,DMPK,NR1D2,CPEB2,DTNA,ABCC5,ABCC9,EDNRA,EEF1A2,FRY,YAF2,SH3GLB1,PHF20L1,TNK2,PLEKHO1,LRRC23,RAB9B,RCSD1,RRAGB,EXTL1,KATNAL1,ABCA8,DLC1,ST3GAL6,FECH,PRKAG2,CAP2,FLNC,SGIP1,FOLR2,TACC2,SORBS1,USP16,PDLIM5,DKK3,ZMYND11,GATM,GCK,ADAM28,FREM1,PPARGC1A,BRD8,DCLK2,GNAL,GNAO1,GP1BB,GPR22,RAPGEF4,PLPP7,NR3C1,GRM5,GRM8,BTN2A1,TMEM25,BVES,GUCY1A2,ATOH8,FRMD5,FRMD3,HSPA1L,ICA1,IDH3A,ZNF181,IL6ST,BRINP3,ITGAV,JAK2,KCNH2,KCNJ5,KCNJ11,KPNA5,KTN1,LAMA2,HECTD2,SMAD9,MAP4,MARK1,MBNL1,ADAM11,IL17D,TM6SF1,MEF2C,MEIS1,MEIS2,MITF,MSRA,CTNNA3,MYH6,MYH7,MYL3,NCAM1,NDUFA5,NFIA,NPPA,HCN1,PDE4D,PFKFB2,PFKP,PGAM2,DUSP26,PLCL1,FXYD1,SCHIP1,MAPK4,PROX1,MASP1,LRRC49,SIDT1,PTPRE,TMEM255A,ZCWPW1,RBBP6,SEC61A2,RPE65,PAQR6,ZNF568,RXRG,ATXN1,SCN2B,MRAS,SUPT20H,SH3BGR,SH3GL3,CPEB3,MYO18A,FHOD3,SLA,SLC4A3,FAM81A,LIMS2,SLC6A9,SLC8A1,SLC8A3,SCMH1,SLC20A2,CPEB4,SORCS3,SMARCD3,SNCA,PALLD,TNIK,UNC5B,ARHGAP26,SPTB,LMO3,EPB41L3,DIP2A,VPS13A,POPDC3,PDLIM2,KLHL4,DOCK9,PCDHB10,PCDHB7,PSD3,TLL2,TMOD1,TPM1,TPM2,SYNPO2,TRH,TRPC1,TRPC3,OSBP2,VIPR2,NSD2,ETNPPL,PCDH20,ZNF32,ZNF540,NDRG4,ZNF154,REEP1,SLC30A3,SHD,PRDM8,RNF103,PPP1R3F,CAB39L,MPPE1,EPM2A,HRASLS,ST7,PHTF2,MSRB3,SSPN,DPF3" Coexpression 15374961-TableS2 Human Brain_Freije04_595genes GeneSigDB 7.52E-20 8.70E-16 2.42E-17 2.40E-16 152 474 "SERPINA3,ACTN1,NDRG2,ADCY2,DSCAML1,CCDC85A,ADCY8,GALNT13,HHATL,UNC5A,C1QTNF4,CARNS1,SYT13,PDE8B,SLC4A4,ATP2B2,TTC9B,CA12,CACNA1E,PRC1,CBR1,CBS,REPS2,DLGAP1,CHRM1,SYNPR,RAB3C,SLIT2,LHX2,NGEF,TJP2,COL9A3,MFSD4A,CP,AKAP12,MICAL2,VCAN,PDE4DIP,NRSN1,HDAC4,TOX,TMEM130,SV2B,DLG2,HS3ST4,HS3ST2,CALN1,RCAN1,DTNA,EDNRB,FRY,ELAVL2,CALCRL,RCAN2,APC2,NRN1,FGF12,FOXM1,SORBS1,RASL10A,DLL3,NRG3,GABRA1,GABRB3,ZMYND11,JPH4,ARPP21,MTHFD2,ATP8A2,CPLX2,CPLX1,CSDC2,C1QL1,GLRB,PTPN5,UBE2QL1,VSIG4,SYNPO,NEGR1,KCNJ9,KCNN2,KCNN3,KLRC3,STXBP5,MAP4,MAPT,LRP1B,MN1,SCG3,MX1,FXYD7,NCAM1,NCF2,NPTX2,NTRK2,KSR2,ZDHHC22,CNTN3,PDE1A,ENPP2,NALCN,SNX10,FXYD1,PACSIN1,NKAIN4,PTX3,RASGRF2,CRTAC1,RGS4,RNASE1,KLHDC8A,TMEM100,FBXW7,MEG3,KCNIP3,STX1B,RYR3,AMER2,SCN2A,SCN2B,SCN3A,FERMT1,BCAN,NAPB,SLC15A2,SPHKAP,RIMS1,SNCA,MYO16,SPP1,STOX1,SMOC1,SYN2,SYT4,ZEB1,CRB1,THRA,ENHO,HEY2,DAAM2,PRRT1,CSMD1,TPM2,FLRT1,RBFOX3,P2RY12,ZNF711,CELF4,FSTL5,ANKS1B,CBLN2,JPH3" Coexpression M1533 All significantly down-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.33E-20 1.08E-15 2.92E-17 2.90E-16 229 830 "FMNL2,TMCC3,MTUS1,HECW2,OSBPL8,TAOK1,ADGRF5,SPOP,FAM135A,APBB2,SHROOM2,PRX,ARHGAP5,ARRB1,B3GALT2,SEC11C,DCAF5,GPR146,CFLAR,DST,MTMR2,THSD7A,CALM1,CAMK2D,CAST,LDB2,KRIT1,CD38,MYOM2,LRBA,LRRFIP1,JAM2,KMT2C,TPP1,QKI,ARMC8,COL4A5,ACBD5,NECTIN3,CLOCK,NCOR1,SNCAIP,CSNK1G3,PDE4DIP,PPP1R16B,CYBB,DOCK4,MYADM,RIPOR2,ARHGAP24,ZFYVE16,LIN54,AIF1L,SIRPA,DBT,PITPNC1,ZEB2,MAGI2,RABGAP1L,TMCC2,KBTBD11,CPEB2,SLC12A6,DPYSL2,RCAN1,DTNA,DNAJB6,E2F5,EBF1,TSPAN5,EDNRB,HIPK3,KLHL5,TMTC1,FRY,OPTN,SH3GLB1,PHF20L1,MBNL2,EML1,CALCRL,RCAN2,EPHB1,SPEG,ARMCX1,ACSL4,DLC1,ST3GAL6,MED12L,FLT1,SGIP1,SORBS1,FAM49B,ST6GALNAC3,FYN,STAG2,GABRA4,ILDR2,GALC,IQGAP2,SYT17,PCDH17,MALT1,FERMT2,GPD2,STON1,LPAR4,RAPGEF4,PARD3B,GRM7,GSN,GUCY1A1,GYG1,ZHX1,SYNPO,AGFG1,HSP90AA1,IL6ST,ITPKB,JAK1,LIFR,LIMS1,LMO2,MAPT,MARK1,SHC3,MEF2C,KITLG,MYO6,NEK1,PDE2A,PDE4B,PDE4D,PFKFB3,ABCB1,SERPINI1,RETREG1,PLCL1,SMIM7,RC3H2,SCHIP1,ING3,SLC36A4,MINDY2,SNRK,PTPRB,PTPRG,PTPRO,RIPOR1,TUG1,ARID4A,RBBP6,ZDHHC14,TTLL7,CCDC82,KIRREL1,PCMTD2,CLIP1,ATXN7,SCN7A,GALNT10,SGK1,ITSN1,FAM102A,MYO18A,FNDC3A,ABLIM3,PREX2,BTBD3,EPN2,SLC12A2,CPEB4,MBD5,LMBRD1,PALLD,FAM126B,USP33,SON,SP2,KDM4C,TEX2,ARHGAP26,KIF1B,DDN,TROVE2,ITPRID2,NXT2,ST5,MPRIP,KANK1,SULF2,FGD4,VPS13A,TMEM150C,TACC1,MTCL1,FAM208A,PDLIM2,ADGRL3,WASHC4,PSD3,PUM2,TNS2,GPRIN3,FRYL,TEK,C18orf54,AP4E1,TGFBR3,TLR4,HEY2,DAAM2,TPM1,NPL,TRPC1,SSBP2,TUBB2A,SGK3,TUBB1,RICTOR,SPIRE1,RNF103,SEMA3B,PLSCR4,GOPC,FAM13C,CERS6,MSRB3,FRMD6" Coexpression M2013 Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.06E-19 1.22E-15 3.22E-17 3.20E-16 145 445 "SYN3,NCKAP5,SLITRK1,ADCY6,ADD3,ZNF608,CC2D2A,SPARCL1,ABCD2,ANK2,CNTNAP1,LRRC4C,B3GALT2,NOL4,ATP6V1G2,TTLL9,BCHE,BCL2L2,SYNJ2,CDH10,CHM,NRXN1,TPP1,STOML1,AKAP7,PCYT1B,COL4A5,SUMF2,SMARCAL1,RTTN,CREB5,NCAN,CTNND1,KIAA0408,HDAC9,KATNAL2,TCAF1,DGKB,ZEB2,MED24,ALKBH8,SRGAP3,DLG4,CD99L2,SLC12A6,DTNA,FIS1,KLHL5,FAM13A,MBNL2,LPAR6,TMEM35A,ETV1,EXTL1,ABCA8,TOMM40L,ATP13A4,SYT3,TRIM16,BRSK1,MEGF10,GABRG1,GHDC,GAP43,PPARGC1A,ZNF276,LOXL3,GPM6A,LPAR4,GPER1,PLPP7,GRIK5,GRM3,ADAMTS6,SCRG1,CPT1C,HSPA1L,LIX1,LRRTM3,KCNA4,KCND2,LRRC4B,MT3,LINC00672,NDP,RCOR2,IDNK,DDR2,P2RX7,PBX1,PCDH9,PDE1A,PDE1C,PDE4B,GNG2,SERPINI1,C11orf49,LRRN3,PPP2R5C,MAPK10,WBP1L,PTN,ZIK1,PPP2R3C,SUSD4,RFX5,TMEM100,ARMH4,FBXW7,ADAL,TRAPPC13,S100B,DGLUCY,CSRNP3,TRIM46,YPEL4,SLC15A2,MTERF2,CPEB4,INTS9,SOX5,TSNAXIP1,SRPK2,ZC4H2,ST5,ADHFE1,ACSBG1,ARHGEF9,SYT1,EHBP1,TPCN2,ACTR6,SMUG1,ZMYND8,RFTN2,ZKSCAN5,DNAJC12,TSPAN11,CFAP52,FTSJ1,DNALI1,MDH1B,NAV3,C12orf4,SSPN" Coexpression 15665281-Table2 Human Brain_Wong05_96genes GeneSigDB 2.43E-19 2.82E-15 7.22E-17 7.17E-16 43 67 "SLC12A5,ALCAM,GAS7,ASCL1,BSN,CACNA1A,CBLN1,DCLK1,CDH18,COL9A1,SUSD5,NCAN,DLG4,TSPAN5,CHL1,GABRG2,GNAO1,GRM1,GRM3,GRM5,CELF3,SCRG1,KCNC1,KCNK1,KCNK3,KCNN2,KCNQ2,KIT,L1CAM,TAGLN3,NEUROD1,NEUROD2,NPTX1,PAX6,PPP3CA,RELN,PTPRE,PTPRZ1,SH3GL2,SH3GL3,SYT1,HEY2,FLRT2" Coexpression 17555561-Table2 Human Breast_Mackay07_1395GenesUpRegulated GeneSigDB 3.98E-19 4.60E-15 1.15E-16 1.14E-15 301 1196 "CLK4,ARID1A,KIDINS220,BEND6,OSBPL8,TAOK1,C1QTNF3,SPARCL1,SRPX,GPRASP2,AMPD3,OGT,PPFIA1,ANXA7,KCNAB2,APBB2,APC,DGKZ,UPRT,MIER1,SFMBT2,CASK,ARNTL,DNAH17,CAPRIN2,CCAR2,MTMR9,DOCK11,BBS2,NRP2,CFLAR,KSR1,ST3GAL5,BTK,CA4,CACNB4,THSD7A,LDB2,FMNL3,SYNGR3,SEPT7,ZMYM4,LRRFIP1,CFL2,RCBTB2,CHM,CHN2,CNOT8,JAM2,RAB33A,RAB28,ZFYVE9,TPP1,CLTA,QKI,LY86,AKAP7,SLC25A27,COL9A3,AKAP5,MYRIP,ZNF521,FAM171B,SEC31B,AKAP12,SNCAIP,FEZ1,ARHGEF10,OSBPL3,VCAN,SOCS5,PDE4DIP,RASGEF1C,CYBB,DOCK4,FGFR1OP2,HDAC4,TOX,MATR3,DAPK1,SIRPA,ZEB2,HEPH,ELMO1,BLOC1S6,RABGAP1L,WDR20,DNAH9,DOCK2,DPYSL2,ABI1,ECM2,ABCC9,GOLT1B,AASDH,EDNRA,EDNRB,SH3GLB1,FAM13A,ABI2,LPAR6,ASB3,ELN,EML1,STARD3NL,CALCRL,PAN3,RCAN2,STX2,DNAJC27,TLR7,CEND1,EFEMP1,ATP8A1,SEC24B,FER,KIAA1109,CAMSAP1,SYNCRIP,FOXO3,USP16,PDLIM5,FAM49B,PNMA2,OGA,FYB1,STAG2,GAB1,GALNT15,TRAF3IP2,ZMYND11,GALC,RAPGEF6,NCKAP1,IQGAP2,GCK,ARFIP1,WASHC2A,SESN1,GGTA1P,MALT1,LYVE1,TCERG1,SPIN1,GLS,INSM2,LNX1,GPR34,EML4,RAPGEF4,DIDO1,NR3C1,GUCY1A1,VSIG4,HSD17B1,IRF8,SCIN,IL6ST,ITGAV,JAK2,KCNF1,KCNK2,STXBP5,LAMP2,ARHGAP12,MBNL1,MBP,MEIS2,KITLG,MID1,MKLN1,AFF1,MMP16,BLOC1S2,MTR,RSPO2,MYO5A,MYO9A,NDP,NEK1,SLC11A2,OLR1,PDGFRA,SERPINE2,PIK3R1,RETREG1,PCDH18,PPARA,CRLS1,PPP3CB,PPP3CC,PRKAB2,MAPK10,LAMA1,PTAFR,MTMR10,ELOVL2,ZSCAN32,PEX2,PPP2R3C,FAT4,HKR1,SLC6A15,REV3L,GTDC1,KLHL11,RNASEL,RNH1,RPL15,WLS,SATB1,ATXN1,PEAR1,GALNT10,SGK1,ITSN1,DOCK10,FNDC3A,ST6GAL1,SLC1A2,SLC1A3,PREX2,SLC8A1,SLC8A3,CCDC88A,SLIT1,RCOR3,TTC17,IFT122,FAIM2,TMCC1,PDZRN3,SON,SPATA7,ZCCHC24,KDM3A,GLT8D1,MYCBP2,KDM4C,ZNF423,ARHGAP26,TAB2,CLASP2,ZNF302,ZC4H2,SEPT8,RGL1,KLHL7,SYT11,PRRC2C,PLCB1,SYPL1,TACC1,MCF2L,CAMSAP2,AGTPBP1,TCEA1,WSCD1,TCF4,ZEB1,TRIM2,TCF12,WDR7,SYNE1,ARHGEF12,PUM2,CRTC1,SIK3,DICER1,SIRT1,KHDC1,AP4E1,ZMAT3,ZNF106,SLC44A1,TJP1,TLR4,ZFP91,PIK3R5,TP53BP2,SYNPO2,TRPC1,ZMYND8,TSC1,SSBP2,RFTN2,UBE3A,PITPNB,PLEKHH2,ZNF24,TCEAL7,ZFAND5,SMARCAD1,WNK1,CSDE1,ADAMTS9,JMJD1C,SSPN,FRMD6,RNF146,LAS1L" Coexpression 19658189-TableS4 Human EmbryonicStemCell_Xu09_1801genes GeneSigDB 5.79E-19 6.70E-15 1.63E-16 1.62E-15 346 1430 "ASPHD1,ACLY,TKTL1,XKR4,SLC25A25,CSMD3,FMNL2,ADARB2,TMCC3,ADD3,CDC7,PLEKHH1,FZD9,UNC5A,NLGN4X,PCDH19,OSBPL6,ZNF578,SEMA6A,C1QTNF4,BCAR3,UNC79,SYT13,PDZD4,PPFIA1,APBA2,KCNAB2,SHTN1,CASK,TMEFF1,SPTBN4,TMEM108,STX16,ATP2A2,KIF1A,ADGRB1,BLM,PROM1,LDHD,GYG2,GPC2,BSN,CA4,CA12,CACNG1,DIRAS1,SYT6,BRSK2,RHBDL1,CBS,CLDN10,CCKBR,MTMR7,INA,SLC16A4,CD86,SYNGR3,CD38,CDC25B,LARGE1,DLGAP1,CRLF1,NUMBL,CHGA,RAB3C,JAM2,NRXN1,NGEF,SULT4A1,ANKRD35,COL9A2,LETMD1,COL9A3,SLC4A7,SLC4A8,GAL3ST1,TCEAL2,RTTN,SLC32A1,CRYBB1,CRYM,SIPA1L1,GALNT9,CNTNAP2,SLITRK5,PPP1R16B,CTH,ARHGEF4,RIMS2,RASSF2,DGKG,DAPK1,SPOCK2,PITPNC1,ELMO1,CNIH3,MFAP3L,KIF19,HS3ST2,CDON,FAM57B,DPYSL2,ARRDC4,DTNB,E2F5,SEZ6L2,HEYL,CACNG7,CELSR3,KMT5B,ABI2,IRAK4,ELAVL2,PCOLCE2,OLIG2,EPB41L2,SEZ6,EPHB1,SLC43A2,HSPA12B,F3,TBC1D16,TUBB3,TUBB4A,EFEMP1,TESK2,OLFM1,FGF13,FGFR1,BAIAP2,MAD2L2,FGR,SCARA3,HPCAL4,ZMYND15,SEMA4D,FLT1,DLL3,B3GAT1,MPP6,GABBR1,GABRA4,GABRB3,GABRG2,JPH4,GAP43,MTHFD2,SYT17,ACSS1,GCNT2,GDF1,RND1,GLDC,GLI2,CBX1,KIAA1958,GNG3,GNG4,PSRC1,GPM6B,TDRKH,FUT10,B4GALNT4,GPR17,GPR19,STMN2,GRB10,DIDO1,ADAMTS8,CIT,GSTM5,SOX21,PSIP1,FAM107A,WIF1,IGSF21,ACOT7,ATCAY,ZNF546,HES5,INSM1,TUBB2B,KCNA1,KCNB1,KCND1,KCND2,KCNK1,KCNN1,KCNQ2,KIT,CAMK2N2,MATK,MATN3,MBP,CHST6,MMP16,WDR49,CD200,BCO1,MT3,SAMD14,MX1,MYT1,NDP,RCOR2,NEFH,NELL2,NFIX,NFYA,NODAL,NPY,NPTX1,NPTX2,NTRK3,ZDHHC22,KCNK10,PAK3,PCDH8,PCSK1,PCSK5,PDE2A,ENPP2,PDPK1,PDYN,PFKFB4,SERPINE2,SEMA5B,CAMKV,A2ML1,SNX10,PLP1,PLXNB3,PSAT1,MAGEL2,SPATA6,EPB41L4B,PPP2R2B,PPP2R2C,PRKCZ,HYDIN,PRODH,KLK6,LAMA1,STK32A,PTPRB,PTPRE,PTPRN,PTPRZ1,ZNF493,RASGRF2,SLC6A15,RET,RGS7,RGS10,RIT2,RNASE1,NUDT11,RORB,SNX22,NEK11,GLDN,EMID1,SOX8,KCNIP2,KCNIP1,RTN1,SALL1,LRFN5,HES6,SOX6,TRIM46,GALNT10,ASRGL1,SH3GL2,PPM1E,FBXO11,SLC1A2,SLC1A6,SLC8A2,SLCO1A2,SLIT1,MAST1,TRERF1,SOX3,SOX10,NMNAT2,ZNF423,KIF1B,NFASC,SST,SSTR1,NXT2,FCHO1,STXBP1,ACSBG1,KLHL7,ABCC8,RHBDL3,NUDT10,SYN2,SYP,SYPL1,COBL,SEMA4A,ROBO3,CNTN2,WWC1,PCDHGB7,SLC19A3,AKNA,ARHGAP9,TEX15,VWCE,TEK,ITGB3BP,SLC44A1,FBXL16,GALNT17,TIE1,TIMP4,HEY2,TNFRSF1B,TNNT1,TPD52,NPL,TPM4,RPRM,UGT8,PLEKHH2,VGF,MICAL1,KLC2,KCNK12,ZIC2,ZIC3,TRIM9,LRP8,RGMA,GDPD5,SCG2,HPS4,SLC17A7,KCNAB1,VANGL2,CPNE4,LAS1L" Coexpression M2116 Genes correlated with neural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.08E-19 7.04E-15 1.68E-16 1.67E-15 63 129 "NDRG2,ADD3,PPFIA2,ANXA7,BCAS1,SHTN1,ARRB1,CA4,CAMK2G,CCK,REPS2,CDC42,CDR1,CHN1,CPNE6,TCEAL2,NSL1,CRYM,ATRNL1,DYNC1I1,EDIL3,ANKRD46,ACSL4,HPCAL4,FAM49B,FUT9,RND1,GPR22,GRM1,GRM3,GABARAPL2,HPCA,KCNJ3,KCNK1,MBP,MYBPC1,LYRM9,ENPP2,SERPINI1,PLCL1,FXYD1,SCHIP1,PPP1R1A,PRPSAP2,ROGDI,FEZF2,RERGL,SLC30A10,SH3GL2,SH3GL3,SLCO1A2,USP33,EPB41L3,POPDC3,AGTPBP1,TPM3,NTSR2,TTPA,SGK3,UGT8,BEST1,ETNPPL,ANKS1B" Coexpression 19377508-SuppTable1 Human Lymphoma_Chin09_1201genes GeneSigDB 1.64E-18 1.90E-14 4.42E-16 4.39E-15 197 695 "TMEM132B,CCDC85A,RNF150,PTCHD1,SLC24A4,AP2A2,GPR158,HECW2,WDR35,SPARCL1,BCAR3,SYT13,PITPNM2,AMPD3,LRCH2,EP400,FGD2,PPFIA2,BCAS1,ARNTL,PLA2G4C,ZBTB10,SLC4A4,AZGP1,MPDZ,RGS9,CFLAR,SGCE,CBS,SLC16A4,CD38,ADGRG1,CHI3L2,JAM2,LHX2,NMT2,CNR1,WHRN,AKAP5,ABI3BP,MYRIP,FEZ1,PDE4DIP,PPP1R16B,ARHGEF4,CTNND1,CTNND2,RIMS2,GPSM1,CX3CR1,MYADM,SPOCK2,SIRPA,KLHL3,TMCC2,DLG2,DMD,HIPK3,EBI3,PLXNC1,PCOLCE2,CALCRL,EPB41L1,EPS8,ERBB2,PIPOX,DUSP27,ABCA8,TBC1D16,TUBB3,EFEMP1,FGFR1,DPYSL4,KHDRBS3,FYB1,CHL1,ARPP21,ADAM28,GFRA1,PPARGC1A,GPD1,GPD2,GPR19,RAPGEF4,GRID1,RFFL,GRIK2,GRIN2C,GRM8,PTPRT,FAM19A2,ADAMTS6,GUCY1A1,GUCY1B1,HBA1,BACH2,SYNPO,IGFBPL1,ATCAY,IL6ST,ITPKA,JAK1,KCNMA1,KCNN2,KCNQ2,LSAMP,SMAD1,GPR155,MAP6,AQP11,MEIS1,MSR1,CTNNA3,MYO7A,NCAM2,NELL2,NTRK3,NUCB2,IGSF11,OLR1,OMG,P2RX7,PBX1,PCDH9,PDE4D,GDAP1L1,SERPINE2,SMOX,PURG,SCHIP1,EPB41L4B,PKIA,MAPK10,PROX1,PRPH,SNRK,PTPRG,PTPRN2,ZDHHC14,RDX,RAVER2,ROBO1,ROBO2,TMEM100,UEVLD,ADAL,RPS6KA2,LGR4,KCNIP2,RTN1,RXRA,SCN3A,LRRTM4,SMPD3,SELL,MRAS,HSPA4L,NTNG1,MAGI3,BCAN,NLGN1,BTBD3,YPEL4,SHANK2,SLC22A4,SLN,SORCS3,NPAS3,MLC1,ABCC8,PLCB1,SYT4,POPDC3,ATP11A,TCF7L2,TPCN2,TF,CRB1,CDH22,HEY1,TLR4,TMOD1,TNNT1,TPM2,NEIL2,TRPC1,PPIL6,SSBP2,LRTM2,TRIM9,FSTL5,MDH1B,NAV3,NAV2,SSPN,KLHDC1,DPF3" Coexpression M13522 "Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.00E-18 1.04E-13 2.37E-15 2.35E-14 149 483 "OSBPL8,SPOP,BCAR3,OGT,CDC42BPA,PPFIA1,PKP4,PARG,CASK,RGS20,CDK13,NCOA1,NUMB,EIF4G3,ATP2B1,BARD1,BLM,DST,ARHGEF7,FUBP1,KRIT1,USP6,CDC27,ZMYM4,FOXN3,ZFYVE9,NMT2,TJP2,QKI,NIPBL,SLC4A7,CLOCK,C2CD2,RBM39,NCOR2,SOCS5,FAM169A,PUM1,GAPVD1,DAPK1,ZNF804A,CEP170,ABI1,MAMLD1,DYRK1A,TSPAN5,EGFR,EPS8,F3,DLC1,SEC24B,KIAA1109,CAP2,FOXO3,STAU2,MPP6,FYN,ZMYND11,SEPT9,WASF3,GLRB,ZNF638,FERMT2,NR3C1,MAP4K5,RBPJ,KIF2A,KIF5C,ARHGAP12,MARK3,MBNL1,MEIS2,MID1,MKLN1,AFF1,CNOT4,OPA1,PCMT1,CCSER2,FTO,STRN3,SCHIP1,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,PRKACB,PKN2,PTK2,REV3L,RGS7,CLIP1,ATXN2,SEC14L1,SCAF8,ITSN1,CHD9,FNDC3A,R3HDM2,RAB3GAP1,LIMCH1,ZHX3,MYCBP2,SRPK2,TAB2,CLASP2,LARP4,ZC3H4,PRRC2C,VPS13A,KAZN,MTCL1,DNMBP,CAMSAP2,FAM208A,WWC1,FBXW11,TBL1X,EHBP1,SATB2,TCF7L2,ZEB1,TRIM2,TCF12,WASHC4,CLASP1,WDR7,PUM2,FRYL,SIK3,TIAM1,R3HDM1,PARD3,KAT6B,TP53BP2,RBFOX2,TRIO,ZMYND8,HIRA,UBE3A,FLRT2,WRN,XPO1,XRCC4,USP32P2,EVI5,KAT6A,CERS6,FXR1" Coexpression M5547 Age up-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.05E-17 1.22E-13 2.70E-15 2.68E-14 97 262 "ADD3,AGT,BBOX1,PPFIA1,RGS20,ASCL1,ALDH4A1,SLC4A4,BMP7,IL33,DDR1,CAST,CBS,RGN,QKI,NIPBL,IQCK,COL4A5,ABCG1,LRIG1,VCAN,PDE4DIP,GREB1,TCAF1,RASSF2,ZEB2,HEPH,MFAP3L,CEP170,GNE,ECM2,SH3GLB1,PLXNC1,OLIG2,EFS,EYA1,EFEMP1,FGF1,FGFR3,AMOTL2,PDLIM5,FYN,AHCYL1,GATM,GFAP,FERMT2,ADGRA3,RAPGEF4,GSN,CLASRP,HP,IFI16,ITGAV,ITPKB,KLC1,LAMP2,AFF1,NFE2L2,NKX2-2,NTRK2,OGG1,PIK3C2A,FXYD1,PLP1,PLXNB1,PMP22,SEPT4,ELOVL2,PTPN13,RDX,RNASE1,RYR1,S100B,SCP2,SLC14A1,EFHD1,PALLD,ZCCHC24,ZNF423,ITPRID2,NXT2,KANK1,ACSBG1,MLC1,SYPL1,FAM208A,FRYL,AHCYL2,TNNT1,TP53BP2,TPD52L2,TST,AMOT,WNK1,SEMA3B,EPM2A,SSPN" Coexpression 19808870-ST1 Human Breast_Speers09_780genes GeneSigDB 7.88E-17 9.12E-13 1.98E-14 1.97E-13 206 762 "CLK4,CDC7,ADRA1B,ADRB2,NME5,AK2,TAOK1,MARCH4,ALK,CDC42BPA,MAP4K3,DGKZ,DGKD,CDK10,PDXK,CASK,CDK13,STK33,MARK4,ATM,RIPK1,BMPR1B,CDK5R1,BTK,CDK5R2,DDR1,KALRN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,DGKI,DCLK1,EVI5L,COPB2,CHRM1,TAOK2,TJP2,MAP4K4,PICK1,AKAP7,AKAP6,AKAP5,CDC42BPB,AATK,CSF1R,CSNK1E,CSNK1G3,SOCS5,PITPNM3,APPL1,DGKB,DGKG,DAPK1,DAPK3,IP6K1,AK5,DLG2,DLG3,DLG4,DMPK,RPS6KL1,ABI1,GNE,DYRK1A,SGK2,HIPK3,EGFR,TNK2,SRPK3,EPHA5,EPHB1,ERBB2,ERBB4,SPEG,CDKL3,RPS6KC1,PTK2B,TAOK3,STRADA,TESK2,PPP1R1B,FER,FGFR1,FGFR3,FGR,IP6K2,FLT1,AKAP3,NBEA,CINP,AK8,PDLIM5,TPK1,CAMKK2,NRG3,BRSK1,FYB1,FYN,NEK6,IP6K3,GAP43,GCK,GFRA2,MALT1,GK,TTBK1,DBF4,DCLK2,GRK4,RAPGEF4,CIT,PTPRT,PTPN5,MAP4K5,WIF1,IRAK3,MYLK2,ITPKA,ITPKB,JAK1,JAK2,KHK,KIT,MARK1,MARK3,MATK,MPP2,STK32C,NRBP2,NEK1,NME4,NPR2,NTRK2,NTRK3,DDR2,KSR2,PAK3,CDK18,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,PHKG1,CAMKV,PIK3C2A,PKM,EXOSC10,PACSIN1,PRKACB,PKIA,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRPSAP2,SNRK,PTK2,PXK,STK32A,PTPRG,RASGRF2,RET,RNASEL,RPRD1A,NEK11,RPS6KA2,STK32B,HUNK,MAPK12,SGK1,MAGI3,SEPHS1,CDK5RAP3,MAST1,TNIK,CDK19,SRPK2,MAPK8IP3,NEK4,TTBK2,SIK3,TEK,TIE1,TK2,TLR4,CDK20,TRIO,SGK3,SPHK2,WNK1,MAP3K12,WNK3,WNK2,PAK5,CAMK1G" Coexpression 15720813-TableS2b Human Brain_Hoelzinger05_117genes GeneSigDB 1.09E-16 1.26E-12 2.69E-14 2.67E-13 45 81 "PLEKHH1,KIDINS220,KCNAB2,GPAM,MADD,ATP2B1,BCL2L2,ARHGEF7,CAMK2D,LDB2,INA,CHN1,CNTN1,CRHBP,CRYM,FRY,EFNB3,RCAN2,DKK3,GABRG2,GFAP,GPR19,GRIA1,HLF,KCNK1,MEF2C,MOBP,TAGLN3,NELL2,NPTX1,OPCML,PDE1A,ENPP2,SERPINI1,PRKCB,KLK6,PTPRN2,RGS7,SHANK2,SMARCC2,SNCA,BEX1,NEK4,R3HDM1,FIP1L1" Coexpression M1551 Genes whose splicing in neocortex was most affected by knock out of NOVA2 [GeneID=4858]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.57E-16 1.82E-12 3.76E-14 3.73E-13 31 43 "ANK3,CASK,ATP2B1,CACNA1B,CAMK2G,DNAJB5,MAP4K4,EPB41,EPB41L2,EPHA5,GPHN,STX2,TACC2,CHL1,GRIK2,GRIN1,GPR45,IDH3B,KCNMA1,KCNQ2,LRP1B,LRP12,RAP1GAP,NTNG1,CLSTN1,SPTAN1,EPB41L3,NCDN,CLASP1,TPM3,CADM1" Coexpression 17660535-TableS4b Mouse InnerEar_Sajan08_2230genes GeneSigDB 1.59E-16 1.84E-12 3.76E-14 3.73E-13 433 1948 "DGCR6,ABCF1,ACLY,NDRG2,ADCY2,ADD1,ADD2,AXIN2,SORCS1,SNX30,AP2A1,OSBPL1A,ALAD,SPARCL1,SPOP,ARHGAP20,AMPH,OGT,ANK3,FGD2,PKP4,APBB2,APLP1,GPAM,APP,SEMA4G,PRX,ARHGAP5,ARNTL,ARRB1,ASPH,RASL11B,ALDH4A1,ATP1A2,MYOM1,RIPK1,SEC11C,RGS9,NRP2,ST3GAL5,FUBP1,MTMR3,RAB29,FOXK1,DDR1,CACNA2D1,HAP1,CAMK2G,TRIM41,CANX,HIP1R,CBLN1,CBR1,CLDN10,CCNH,USP2,SCARB1,CDK11B,LRBA,CDH2,ZMYM4,LARGE1,LRWD1,CRLF1,CACNA2D2,PLEKHB1,KMT2C,RAB33A,CLCN3,COG1,CLU,TJP2,FADS2,MAP4K4,NIPBL,LETMD1,COL9A3,SLC4A7,IGDCC3,CHD1L,NECTIN3,PREPL,AKAP12,HAPLN1,RNF14,HINFP,NCOR1,CRYM,TENM4,SEC24C,LRIG1,FEZ2,FEZ1,ARHGEF10,VCAN,PDE4DIP,GREB1,PUM1,RIMS2,GPSM1,MYADM,TOX,TOMM20,AIF1L,DBN1,PITPNC1,MYEF2,HP1BP3,C2CD2L,BLOC1S6,DDX46,SNAP91,PARD6A,SRGAP3,NTM,G3BP2,FAM107B,DLX1,DYNC1I1,DNM2,SLC12A6,ATN1,PDCD6IP,DUSP9,DYRK1A,ST8SIA3,HIPK3,EEF1D,APH1A,EGFR,KMT5B,AASS,EIF4G1,EIF5,COPS4,BSCL2,STARD3NL,RCAN2,RCSD1,RASL12,ADGRV1,EZH1,ARMCX1,ACSL4,PTK2B,TUBB4A,TAOK3,SCML2,PRMT5,GTF2IRD2,POLR1B,FGF13,FGFR1,CAMSAP1,SCARA3,UBE2E3,FOXG1,PCYOX1,FOXM1,SEMA4D,ANKFY1,NOP56,FLYWCH1,NELFCD,COQ5,TACC2,SORBS1,PDLIM5,KHDRBS3,DACH2,FUT9,SARAF,FYN,STAG2,GAA,CHL1,TRAF3IP2,FAM184B,ZMYND11,B4GALNT1,GAP43,MTHFD2,INPP5K,DNER,NEU3,GBX2,GCNT2,GFER,GFRA1,USP19,GHR,DHRS4,CRCP,TCERG1,RNPS1,TNRC6A,GPT2,GP1BB,RAPGEF1,GRIA2,GRIA4,GRM8,GSN,GSTM5,GSTT2,SOX21,PSIP1,MAP4K5,ZHX1,FRMD5,AGBL5,HNMT,ICA1,MSL1,IDH3A,NKD1,LRRTM1,ITGAV,KCND2,KTN1,LAMP2,PAXBP1,ZFYVE27,MARK1,MAT2A,MATK,MBNL1,MEIS1,MEIS2,MEST,MITF,MKLN1,AFF1,CCDC80,MSRA,NRBP2,DDX25,RSPO2,MYH6,NAP1L1,NAP1L2,NAP1L3,NCAM1,RCOR2,NEUROD1,NRCAM,NRDC,NTRK2,NTRK3,NUCB2,PCMT1,PCSK5,PDCD2,PDE4B,ENPP2,PENK,ZDHHC8,SERPINE2,SEMA5B,CAMKV,SNX10,PKM,PLCD1,PLP1,STRN3,EXOSC10,POLR2F,IRX1,PPM1B,PPP2R2B,PRKCZ,MAPK3,GDPD1,MASP1,BCAS3,PSMA6,LRRC49,LAMA1,QRICH1,PTCH1,ANKHD1,MTMR10,PTHLH,PXK,PTN,OCIAD1,PTPRD,EML5,PTPRE,TTC13,PPP2R3C,SUSD4,RAP1GDS1,OXR1,RASGRF1,RBBP6,ZDHHC14,SLC6A15,REV3L,ZDHHC4,RGS3,RLBP1,RNF220,RNASEL,ZFHX4,RNH1,ELP2,PCMTD2,EMID1,RTKN,RTN1,RXRA,RXRG,S100B,SAFB,SARS,SATB1,TNFRSF19,SEC14L1,SOX6,GALNT10,SFPQ,ASRGL1,PUF60,SCAF8,SCG5,SH3BGR,ITSN1,FAM102A,NTNG1,FNDC3A,FHOD3,SLC2A5,LIMS2,SLC6A8,CCDC88A,SLC11A1,SLC12A2,SLC15A2,ATF7IP,ZKSCAN3,SMARCA4,SMARCD3,LIMCH1,SNCA,SNRPN,USP33,SOX5,SOX10,FNBP1,SOX11,KDM3A,SP4,MYCBP2,SPP1,ERC1,SRPK2,CAMTA2,SMOC1,ERBIN,MPRIP,PHLDB1,SULF2,NSFL1C,JMJD6,VAMP1,TAC1,PDLIM2,WWC1,TCF4,ZFP90,CUX2,TRIM2,TCF12,OBSL1,ARHGEF12,PUM2,ZMAT3,THRA,TMEM9,NACC2,HEY1,CBX5,HEY2,BEX4,ANKRD24,PRRT1,PARD3,TNNT1,TPD52,TPM1,TPM3,TRIO,TRPC1,TRPS1,RUSC1,TMPRSS5,SSBP2,RFTN2,HSPBP1,TTC3,HIRA,UBC,UBE3A,AMOT,UCHL1,MTCH1,PCDH20,ZFP37,ZBTB14,SPHK2,CELF4,SH3GLB2,ZFAND5,SMARCAD1,SLC30A4,PMEPA1,MAP3K12,CSDE1,CIAPIN1,SEMA3B,ITM2C,PCBP4,WNK2,MVB12B,ST7,HNRNPA3,PHTF2,JMJD1C,SSPN,RNF146,AP3B2,SPATA13" Coexpression 19658189-TableS5 Human EmbryonicStemCell_Xu09_622genes GeneSigDB 3.32E-16 3.84E-12 7.69E-14 7.64E-13 145 483 "ACTN2,NDRG2,ADCY5,ADCY6,RNF150,ADRB2,MTUS1,GPR158,AGT,ANK2,MYH7B,PPFIA4,ANXA7,CPNE5,PLA2G4C,CADPS,ASPH,SLC4A4,ATP2A2,ATP2B1,SLC2A11,MYOM1,GPR146,CACNB2,CAMK2A,CAMK2B,CAMK2D,CAPN3,CAST,USP2,RGN,MYOM2,CDH2,QKI,AKAP6,PNKD,CRY2,MICAL2,ARHGAP24,KLHL3,DMD,DMPK,NR1D2,CPEB2,DTNA,ABCC9,EEF1A2,FRY,YAF2,PHF20L1,RAB9B,RCSD1,ABCA8,DLC1,FECH,PRKAG2,CAP2,FLNC,FOLR2,TACC2,SORBS1,USP16,PDLIM5,DKK3,PPARGC1A,GP1BB,GPR22,RAPGEF4,PLPP7,NR3C1,TMEM25,BVES,ATOH8,FRMD5,FRMD3,ICA1,IDH3A,JAK2,KCNH2,KCNJ5,LAMA2,MAP4,MBNL1,ADAM11,TM6SF1,MEF2C,MITF,MSRA,MYH6,MYH7,MYL3,NFIA,NPPA,PDE4D,PFKFB2,PGAM2,DUSP26,PLCL1,FXYD1,SCHIP1,PROX1,MASP1,SIDT1,PTPRE,ZCWPW1,RXRG,ATXN1,SCN2B,MRAS,SH3BGR,CPEB3,MYO18A,SHC4,FHOD3,SLC4A3,FAM81A,LIMS2,SLC6A9,SLC8A1,SLC20A2,CPEB4,SMARCD3,PALLD,TNIK,ARHGAP26,SPTB,POPDC3,PSD3,TLL2,TMOD1,TPM1,TPM2,SYNPO2,OSBP2,VIPR2,ZNF540,NDRG4,REEP1,SLC30A3,PRDM8,RNF103,EPM2A,MSRB3,SSPN,DPF3" Coexpression M2882 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.61E-15 1.86E-11 3.64E-13 3.62E-12 97 280 "FMNL2,ADCYAP1R1,NME5,C1QTNF1,ANK3,PLA2G4C,ASTN1,ATP1A2,NOL4,BMP7,CDK5R1,CALB1,KCNAB3,DLGAP2,CDR1,CHGA,CHGB,KIAA1549L,CSF2RA,ERC2,CTNND2,ST18,DOCK4,ARHGAP24,SNAP91,NTM,DYNC1I1,USH1C,EN2,RCAN2,ETV1,CEND1,REEP2,ST3GAL6,FOXG1,PNMA2,GABRA1,GABRA3,GFAP,GLDC,TOX3,GPR19,GPR37,GRM1,HAS2,ITPKA,KCNC1,KCNH2,KCNK3,KIF5A,KIF5C,KIT,MMP17,MOBP,SCG3,TAGLN3,NAP1L2,NRCAM,NTRK3,KCNK10,PCDH8,PCDH9,PDE2A,MAPK10,DIRAS2,RELN,PLPPR1,PTX3,FEZF2,SLC6A15,RNASE1,RTN1,TMEM156,SATB1,SCN2A,ASIC4,SCG5,SLIT1,LIMCH1,SNAP25,NMNAT2,SPP1,IDI2-AS1,BEX1,LMO3,CLSTN2,STX1A,SYT1,DNMBP,ZEB1,TRIM2,HEY1,TLR4,UGT8,WNT7A,MKRN3,NAV3" Coexpression 18338247-SuppTable4B Human Breast_Harvell08_428genes GeneSigDB 2.35E-15 2.72E-11 5.22E-13 5.19E-12 104 311 "SLC25A25,NDRG2,PI16,PHYHD1,CDC14B,CDK10,ZFYVE28,ASPA,MARK4,ASTN1,DST,IL33,CAPN3,CDO1,JAM2,FHL5,CNR1,SLC25A27,ABI3BP,NRG2,NECTIN3,SLC35F1,CREB5,PDE4DIP,CST3,PPP1R16B,PLCXD3,GREB1,BOC,HDAC9,GPRASP1,LONRF1,MATR3,CHRDL1,RAB39B,EDNRB,FAM13A,RASA4,F3,ABCA8,FCGRT,OLFM1,FHL1,GAP43,DNER,WDFY3-AS2,GRIA1,FAM107A,PADI2,AGFG1,ITGA7,KPNA5,SMAD9,MAP6,MATN2,SAMD5,SESN3,BEX5,FXYD6,P2RY13,NOVA1,NTRK3,CLDN11,PDE1A,PDE1C,PDE2A,ENPP2,ABCB1,PIK3R1,PLCB2,FXYD1,LRRN3,PPP3CA,RELN,PTPRN2,REV3L,RGS12,RERGL,KIRREL1,TMEM100,WLS,RTN1,LRFN5,SCN7A,CNKSR2,NLGN1,ARHGEF40,SNRPN,PLCB1,SYN2,TAL1,ADGRL3,PCDHGC5,SLC35G2,PRRT1,SYNPO2,TRPC1,ZNF781,ZBTB16,GDPD5,NAV3,WNK3,MVB12B,DNAH10" Coexpression M2573 Genes consistently up-regulated in mammary stem cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.47E-15 2.86E-11 5.40E-13 5.36E-12 144 489 "SORCS1,PCDH19,OSBPL6,C1QTNF4,SRPX,ARHGAP20,LTBP4,LRCH2,PRX,ARNTL,ATP2A2,BACH1,MPDZ,NRP2,BMP7,DST,CACNB4,ARHGEF25,CRLF1,JAM2,SLIT2,QKI,COL9A2,ABI3BP,CNRIP1,NECTIN3,CLIP3,FEZ1,MICAL2,PLCH2,VCAN,PPP1R16B,GPSM1,ARHGAP24,HDAC4,TOX,RUSC2,CCDC3,EDNRB,YAF2,EGFR,EGR3,EPHB1,RCSD1,RASL12,MRVI1,SCML2,FHL1,FLNC,PSD2,SGIP1,SORBS1,NSG1,DKK3,CSDC2,MALT1,FERMT2,RAPGEF1,PTPRT,GSN,RNF165,BVES,WIF1,HAS2,IL6ST,KCNMA1,TTYH2,LIFR,MAOB,MATN2,MBNL1,MEF2C,MEST,NBL1,ZC3H12B,ALDH1L2,NNAT,NPTX2,NRCAM,NTRK2,OXTR,PCDHGC3,ENPP2,SSH1,PKD1,FAM216A,FXYD1,PCDH18,SCHIP1,PRRX1,SDK2,PPP2R2B,EPDR1,RELN,LAMA1,PTPRE,FAM184A,TSPY26P,RFX2,NUDT11,ARMH4,MEG3,KCNIP3,SCN4B,DOCK10,FHOD3,SLC1A3,SLC4A3,SMTN,LIMS2,PKNOX2,SLC6A8,SLC12A4,SNCA,SOX11,ZNF423,TSPYL2,THSD1,ELOVL4,STAC2,PHLDB1,NUDT10,ARC,TACC1,TCF4,TMEM121,TGFBR3,TIE1,TNS1,TPM2,ELP5,TRO,STXBP4,TRPC1,SSBP2,CADM1,FLRT2,VSNL1,WIPF1,TRIM9,TMEM178A,PCBP4,MSRB3,NETO2" Coexpression 18451145-TableS1 Human StemCell_Kumamoto08_2005genes GeneSigDB 7.51E-15 8.69E-11 1.61E-12 1.60E-11 316 1359 "ACHE,CLK4,CSMD2,CCDC85A,OSBPL1A,NR0B1,WDR35,C1QTNF1,CEP126,ANK1,APBB2,GAS7,APLP1,DDO,ZFYVE28,ARHGAP5,ARRB1,RGS20,ARRB2,PLA2G4C,DACT3,ATM,EIF4G3,ATP6V1G2,ADAM23,TTC9B,CFLAR,DST,WASF1,DDR1,CAPN3,CAST,ZNF501,KRIT1,FMNL3,SLC16A4,CBFA2T2,CDC42,ZMYM4,CDH18,DIS3L,SOCS6,CHM,CASC2,KMT2C,RAB28,TPP1,PCYT1B,WHRN,COL4A5,LETMD1,ABI3BP,RTTN,NECTIN3,PREPL,FEZ1,VCAN,SOCS5,PDE4DIP,CNTNAP2,CST3,DZIP3,GAPVD1,ZNF337,KIF26A,DAPK1,DCTN1,DGCR5,PLEKHM1,KLHL3,BLOC1S6,DLG2,DMPK,DNAH9,NR1D2,ABCC9,AASDH,EDIL3,EDNRA,HIPK3,FCF1,CNNM1,SIDT2,EGFR,KMT5B,ASB3,IRAK4,TNK2,TMEM35A,HSD17B14,VPS13B,SEZ6,EPHA5,ANKRD13B,RRAGB,CEND1,SIRPB1,GMPR2,CD320,EZH1,F8,WAC,SH3YL1,SCML2,FCGRT,GTF2IRD2,OLFM1,AMOTL2,FHL1,CAP2,RGPD5,SGIP1,COQ5,DPYSL4,NBEA,POMT1,ATP6V1H,CGREF1,MSANTD4,AP4B1,ZNF512,DKK3,GAB1,GABBR1,GALNT15,GABRB3,GAD1,HBS1L,BRPF3,NEK6,NCKAP1,IQGAP2,STARD10,SESN1,GHR,KIRREL3,RAB40B,GPM6B,STMN2,PARD3B,TMEM25,GSTM5,MAEL,IGSF21,HAPLN2,HNF4G,ZNF491,EID2B,IDH3A,SOWAHA,SCIN,SCRT2,IL12A,INPP1,INSM1,KCND3,KCNJ10,KCNK1,KCNK2,L1CAM,MAP4,MAPT,MDM4,MEST,KITLG,MITF,MMP16,BLOC1S2,RSPO2,LAYN,MYO5A,MYO6,MYO7A,MYO9A,NF1,NFIA,NPR2,NRDC,DDR2,OGG1,OPHN1,PAK3,ETFRF1,PCDHGC3,SERPINE2,PIK3R1,PKD1,SLC25A23,PLTP,ZNF426,PILRA,FA2H,PPP2R5C,KANSL1,MAPK3,SLC26A11,MASP1,VPS13C,ANKHD1,MTMR10,FAM120C,TTC13,RAD52,RALGDS,FAT4,SUSD4,ARID4A,RBBP6,GAL3ST4,REV3L,RNH1,ZNF532,MYH14,CARF,ROM1,NEK11,BAALC,TCP11L1,SCN2A,TNFRSF19,TRIM46,HSPA4L,KIF21A,ITSN1,HKDC1,CHD9,CNKSR2,NLGN1,ABLIM3,SLC1A7,PPP4R3A,FAM214B,ZNF430,SLC12A4,ZNF334,SLC22A4,CPEB4,ZNF667,GKAP1,TTC17,SNCA,MBD5,SNRPN,PDZRN3,USP33,DOP1A,SON,TRERF1,SP2,ZC3H13,LHPP,ATP10B,THSD1,SSTR1,EPB41L3,ERBIN,ST5,TTBK2,RGL1,SULF2,SYT11,VAMP1,ARHGEF9,SYT1,ANKRD28,TMEM136,SMG6,NEU4,ZFP90,TCF7,TRIM2,WDR7,AZIN2,PCDHGA10,PSD3,CRTC1,CYB561A3,VWCE,ZMAT3,TGFBR3,ZNF106,TIAM1,ICAM5,TNS1,WBP2,ZNF384,SYNPO2,PRMT8,SMUG1,ZMYND8,RUSC1,HIRA,SGK3,UBE2H,UBTF,UGT8,PORCN,MICU3,ZNF28,NDRG4,ZBTB16,POLR3H,ZNF189,ZFAND5,PRDM2,CSDE1,GDPD5,ADAMTS9,HPS4,NAV3,CAB39L,PCBP4,MVB12B,ST7,TMEM63C,RSPRY1" Coexpression 16849537-SuppTable2 Human StemCell_Davicioni06_534genes GeneSigDB 7.92E-15 9.16E-11 1.67E-12 1.65E-11 145 500 "ABAT,NLGN4X,NR0B1,LTBP4,ALK,AMPD2,ANK2,PKP4,CDC14B,MARCH3,NCOA1,DST,CACNA1G,DDR1,PTBP2,CCNH,ARHGEF2,DLGAP2,RAB28,CLCN3,NRXN2,CNR1,CRMP1,ABCG1,SNCAIP,DZIP3,ARHGEF4,RIPOR2,DAPK1,BRINP1,JAKMIP2,ELMO1,FBXL5,MAGI2,TRAPPC9,GNE,MAMLD1,EDN3,EEF1D,FRY,SH3GLB1,EGFR,SORBS3,RGS17,OLIG2,ERBB2,PIPOX,NRN1,AMZ2,DLC1,CAMSAP1,SCARA3,SYNCRIP,IQCG,B3GAT1,DENND2A,DISC1,SESN1,TOX3,PRRC2B,RAPGEF4,ACOT7,HSF2,RBPJ,DIPK1A,KCND3,KCNN3,LAMA2,TAGLN3,MYCN,NELL1,NF1,NHLH1,NNAT,NRCAM,NTRK3,PAK3,PCMT1,CDK14,FTO,PMP22,MINDY2,PPP3CA,PTH1R,ELOVL2,PTN,PTPN13,PTPRD,NKAIN1,QDPR,FAT4,ROGDI,ERI2,MORC4,RGS10,NUDT11,ZFHX4,CCDC25,WLS,CLIP1,RYR3,CSRNP3,ASRGL1,FRMPD1,ASAP3,SLC1A3,ARHGEF40,PDZRN3,KDM4C,TEX2,ARHGAP26,KIF1B,RAP1GAP2,CLASP2,CEP68,RGL1,KANK1,SYNE2,SYN2,COBL,ASTN2,POPDC3,KAZN,DNMBP,AGTPBP1,WSCD1,SATB2,DOCK9,PSD3,OBSL1,FRYL,HIF3A,CHST8,AKTIP,HEY1,TRPS1,BCL2L13,VIPR2,MICAL1,ZIC1,SLC38A1,SEMA3B,NAV3,ITM2C,ZNF248" Coexpression M4960 Genes down-regulated in basal subtype of breast cancer samles. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.85E-15 1.02E-10 1.83E-12 1.82E-11 187 701 "ABAT,C3orf14,MTUS1,NME5,KIAA1324,C1QTNF3,SPARCL1,ALCAM,APBB2,DGKD,DDO,BCAS1,ASCL1,ASPA,ASPH,ZSCAN18,BRINP2,CHRD,ALDH4A1,ATP1A2,AZGP1,ADGRB2,RGS11,BMPR1B,BAIAP3,IL33,LDLRAD4,CA12,CACNA1D,CACNG1,CAMK2B,RHBDL1,LRBA,REPS2,DCLK1,CLGN,CACNA2D2,CHN2,RAB26,CNR1,COL4A5,SLC4A7,SLC4A8,CRY2,ABCG1,CSF3R,LRIG1,ATRNL1,CNTNAP2,CST3,DZIP3,KIAA0040,GREB1,FAM131B,CX3CR1,ARHGAP32,SNPH,C2CD2L,MED24,AK5,DLG3,EEF1A2,FRY,EGR3,KCTD3,COQ7,LRRC17,ERBB2,ERBB4,ABCA8,FAM198B,ATP8A1,ZMYND10,FGFR1,FGFR3,EVL,EFCAB2,NBEA,STAU2,TPPP3,IQGAP2,HIGD1B,SYT17,ATP8A2,SRCAP,GFRA1,RND1,GLRB,TOX3,STARD3,GPD1,PCLO,GRIA2,PTPRT,GSTT2,ELOVL5,HNMT,ICA1,MSL1,IGF1,IL6ST,BRINP3,ITGA7,KCND3,KCNJ3,KCNMA1,KIF5C,MAPT,MATN3,MMP17,MYO6,MYT1,NELL2,NF1,NOVA1,NTRK2,NUCB2,TREM2,PBX1,PCSK5,SERPINI1,RETREG1,PLCL1,PLIN1,PLXNB1,LRRN3,PRKACB,SYTL2,SIDT1,PTHLH,ELOVL2,PTPRN2,ACSM5,NKAIN1,QDPR,TRIM68,RET,STK32B,RTN1,DGLUCY,SMPD3,GALNT10,KIF16B,SYBU,ABLIM3,CXXC4,IFT122,FAIM2,KDM4B,TNIK,SPATA7,ZCCHC24,BEX1,PBLD,CLSTN2,SSTR2,SEPT8,GSE1,ABCC8,SYT1,ASTN2,MCF2L,EXOC7,DNMBP,PSD3,THBS4,TIMP4,TK2,KAT6B,TNNT1,ZMYND8,DNAJC12,LMF1,NPDC1,XRCC4,SPHK2,ZBTB16,REEP1,LAMP5,MAP3K12,DNALI1,SLC38A1,SEMA3B,NAV3,KCNAB1,WIPF2,CERS6" Coexpression 19168792-TableS2 Human Leukemia_Figueroa09_567genes GeneSigDB 1.06E-14 1.22E-10 2.14E-12 2.13E-11 127 419 "ACTN2,CCDC85A,SORCS1,PTCHD1,OSBPL6,C1QTNF3,SEMA6A,CDC42BPA,SPTBN4,CADPS,NOL4,TTLL9,BMP7,SYNJ2,CACNA1I,CACNA1A,CACNA1E,CACNA2D1,CBLN1,CCK,CDH8,MAGI1,CHGB,CHRNB2,TMEM155,GALNT9,KIF26A,PABPC5,ZNF804A,LYPD1,GRIN3A,DRD1,CELSR3,ELAVL2,ELAVL3,EML1,EPHA5,ETV1,ZIC4,EFEMP1,ST3GAL6,BAIAP2,FOXG1,CSPG5,ADGRA1,DKK3,GABRB3,GALR1,SALL3,GFRA1,GNAS,GPR34,GPR37,GRIK1,GRIK2,GRIK3,GRM1,SOX21,GUCY1A2,IGSF21,NXPH2,FRMD3,HPSE2,HMGCR,HMX1,IRF8,BRINP3,GPR62,KCNJ9,KCNN2,MAP6,MBP,STK32C,NEFM,NELL1,NEUROD1,NKX2-2,NOVA1,PCDH8,PENK,PIK3R1,TRHDE,PRRX1,POU3F2,PRKCZ,RELN,PTHLH,PTPN13,RASGRF1,DBX2,FEZF2,SLC6A15,RET,AMER2,SALL1,LRFN5,HSPA4L,TRIM67,SORCS3,SNAP25,PDZRN3,SCN3B,SOX3,LHFPL4,KIF1B,NPAS3,ACSBG1,TAC1,SMG6,VWC2,SATB2,PCDHGC5,PCDHB6,TJP1,TPD52L2,TPM1,RGMB,TMEFF2,FLRT2,KCNK12,PCDH20,SPIRE1,CA10,ADAMTS9,WNK3,HRASLS,JPH3" Coexpression 14997935-Table1 Human Brain_Mukasa04_29genes GeneSigDB 1.15E-14 1.33E-10 2.29E-12 2.28E-11 22 26 "ANK3,HCN2,INA,CHGB,RIMS2,SNAP91,CDHR1,TUBB4A,OLFM1,GRM5,KCNQ2,L1CAM,MYH7,MBOAT7,PSD,RGS7,FAM102A,SH3GL3,SNCB,MYT1L,ABCC8,KCNAB1" Coexpression M2012 Genes up-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.31E-14 3.82E-10 6.48E-12 6.44E-11 106 331 "ABAT,NLGN4X,NR0B1,ALK,ANK2,PKP4,CDC14B,ARRB1,MARCH3,NCOA1,DST,DDR1,PTBP2,CCNH,ARHGEF2,DLGAP2,RAB28,CLCN3,CNR1,CRMP1,ABCG1,DZIP3,ARHGEF4,RIPOR2,DAPK1,BRINP1,JAKMIP2,ELMO1,FBXL5,MAGI2,GNE,MAMLD1,EDN3,FRY,SH3GLB1,RGS17,OLIG2,PIPOX,NRN1,AMZ2,CAMSAP1,SYNCRIP,IQCG,B3GAT1,SESN1,TOX3,PRRC2B,RAPGEF4,ACOT7,HSF2,RBPJ,DIPK1A,KCND3,KCNN3,TAGLN3,MYCN,NELL1,NF1,NHLH1,NRCAM,NTRK3,PCMT1,CDK14,FTO,PPP3CA,PLPPR1,ELOVL2,TMEM260,PTPRD,NKAIN1,QDPR,ROGDI,ERI2,MORC4,NUDT11,CLIP1,RYR3,ASRGL1,FRMPD1,PDZRN3,KDM4C,TEX2,ARHGAP26,KIF1B,RAP1GAP2,CLASP2,CEP68,KANK1,SYNE2,SYN2,COBL,ASTN2,POPDC3,DNMBP,AGTPBP1,WSCD1,SATB2,DOCK9,FRYL,CHST8,AKTIP,BCL2L13,VIPR2,MICAL1,SLC38A1,ZNF248" Coexpression M1712 Genes enriched in neurons in the adult mouse brain identified through correlation-based searches seeded with neuron cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.80E-14 4.39E-10 7.32E-12 7.27E-11 38 69 "ADD2,ALCAM,MADD,ATP6V1G2,CAMK2A,CAMK2B,SYNGR3,REPS2,CHGB,CHN1,TCAF1,DPP6,FLYWCH1,NSG2,GAP43,CPLX1,GPR162,GRIA2,GRIA4,DISP2,MYO5A,JAKMIP1,PACSIN1,PRKAR1B,PTPRN,MEG3,RTN1,SH3GL2,NAPB,SNAP25,FAIM2,SNRPN,UNC80,SYP,SYT1,PHF24,UCHL1,NDRG4" Coexpression 16166618-SuppTable3 Mouse Lung_not_cancer_Woodruff05_2037genes GeneSigDB 3.94E-14 4.55E-10 7.47E-12 7.42E-11 302 1301 "CPNE2,ABHD6,FMNL2,TMCC3,ESYT2,ADRB2,BEND6,MTA3,KLHL13,AK2,ALCAM,MARCH4,AMPD3,ANK2,APBB2,CPNE5,CASK,TMEFF1,ARRB1,ARRB2,PDE8B,ASPH,NCOA1,CHID1,ATP1A3,ATP6V0A1,KIF1A,DOCK11,NRP2,BID,PROM1,DST,C1QC,RAB29,FOXK1,CACNA1A,CACNA1D,KALRN,CAMK2D,CAMK2G,VSTM2A,CD86,SCARB1,CD38,AP4M1,ARHGEF2,CDC25B,LRRFIP1,CCPG1,LRWD1,CFL2,SOCS6,CHN2,MS4A7,B4GALT6,LHX2,CLU,FAM189A2,ABCG2,LY86,HOMER3,CNN3,FAM149A,AKAP5,IFFO1,SMARCAL1,CNRIP1,PNKD,ENTPD4,ANKRD44,ABCG1,CSF1,TENM4,FEZ2,SUSD5,ATRNL1,CHD5,PNPLA8,GREB1,USP6NL,CYBB,HDAC9,LONRF1,RIMS3,DGKG,DAPK1,GIT2,ARMCX2,YTHDC1,GSDME,DDX46,POM121,RHOBTB1,FAM107B,ARNT2,DLG3,DMD,CDON,RCAN1,DTNA,EDN1,FEM1B,RASGRP1,KLHL5,FRY,OPTN,YAF2,SH3GLB1,RASA4,PLEKHO1,ENO2,VPS13B,COQ7,SLC43A2,EPS8,DENND4A,SPEG,ETV1,CD320,NRN1,F5,FAM198B,FABP7,ACSL4,PTK2B,ATP8A1,CHST15,FCGRT,SPSB4,BAIAP2,ZMYND15,EVL,FOLR2,TACC2,AK8,ATP6V1H,ATP2C1,GAB1,GABBR1,AHCYL1,B4GALNT1,IQGAP2,SEPT9,ACSS1,SESN1,GFRA2,LYVE1,LPAR4,GPR34,RFFL,NR3C1,MUM1,ATG4C,RASSF8,ZHX1,ELOVL5,SYNPO,HNMT,IGF1,RBPJ,DIPK1A,TUBB2B,ITGAM,ITGAV,JAK2,KCNN3,KHK,STXBP5,L1CAM,LAMP2,LMO2,ASPRV1,SMAD1,PIK3AP1,GPR155,NAT8L,ZFYVE27,MAOB,MATK,MATN2,MBP,IL17D,MEF2C,MEIS1,CD200,ADAM22,MSR1,MYO5A,NAP1L1,P2RY13,NFIX,NPY,NRCAM,NUCB1,P2RX7,P2RY1,TREM2,PBX1,CDK18,PDGFRA,CDK14,ANLN,PMP22,PILRA,PPP3CB,PRKAR1B,PRKCB,SLC26A11,MASP1,SNRK,PTK2,SPDL1,NKAIN1,RAB3IL1,PID1,ZDHHC14,CCDC82,TMLHE,PCMTD2,ATP8B4,PRR5L,ACER3,ST6GALNAC6,SEMA6D,ATXN1,SELL,RASA3,ITSN1,PPP1R9A,DOCK10,ST6GAL1,CLSTN1,SLC1A2,BTBD3,LIMS2,SLC6A8,SLC11A1,SLC12A2,LGI3,SLC22A4,KIF13A,PALLD,FNBP1,SP4,UHRF1BP1L,MYCBP2,TEX2,BEX1,ARHGAP26,LHPP,POGZ,NXT2,RGL1,STAC2,ADHFE1,SEPT3,FAM168A,SYT11,FGD4,SYNE2,SLC37A2,SEMA4A,MCF2L,ALG1,ADGRL3,DMXL2,TCF7L2,ZEB1,TRIM2,AKNA,ARHGAP9,AHCYL2,CYB561A3,ENHO,TIAM1,LRRC8A,FAM124A,CABIN1,TNS1,TPM1,NPL,TST,TTC3,SGK3,CADM1,FLRT2,VAV2,MICAL1,LAT2,TCEAL7,CELF4,AMZ1,SPIRE1,SLC30A4,PMEPA1,LRP8,KCNAB1,FIP1L1,PLD4,RGS7BP,DOCK8,PHTF2" Coexpression M2242 Category A genes: p53-dependent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.20E-14 8.33E-10 1.34E-11 1.33E-10 223 896 "ASIC2,SLITRK1,ADD2,KIAA1324,SRPX,BCAR3,ANK3,APBA2,PPFIA3,ARRB1,ASCL1,STK33,ASPA,SLC4A4,ATP2B1,CADM3,TTC9B,ADAM15,DST,CACNA1G,CA8,CACNA1D,DDR1,CAMK2D,VXN,BRSK2,LDB2,KRIT1,ENTPD2,KCNAB3,EVI5L,MAGI1,CLGN,NOG,UBE2L6,CACNA2D2,CHGA,CHM,RAB3C,KMT2C,RAB33A,CLTC,CNTFR,CNTN1,COL11A2,AKAP5,PNKD,CLIP3,TENM4,NCAN,SOCS5,CALY,APPL1,CMTM5,DOCK4,GPRASP1,RIPOR2,TBC1D5,ZEB2,GUCD1,SNAP91,NTM,KBTBD11,DPH1,DSCAM,SEZ6L2,EDNRA,EEF1A2,FEM1B,RASGRP1,ELAVL3,DMTN,RASGRP2,SEZ6,NCALD,MRPL10,CACNG2,ZIC4,TUBB4A,ATP8A1,ACTL6B,FLNC,TRMO,DKK3,GABRA2,GABRG1,ILDR2,ARPP21,SALL3,MYOZ2,GATM,IGSF5,KIRREL3,LYVE1,RUNDC3A,GLDC,MAP7D2,INSM2,PCSK1N,KCNMB4,GNAO1,GNG3,LNX1,CECR2,ADAMTS8,NR3C1,PTPN5,WIF1,RASSF8,FRMD5,KLF12,SHISAL1,C2orf72,NKD1,DOCK7,KNDC1,ITGA7,CDH20,KCNJ11,KCNN1,KIT,KLRC2,ASPRV1,PACRG,MAG,GPR155,NAT8L,MAP4,MATN3,MEF2C,MOBP,ADAM22,NRBP2,DDX25,MYL3,MYO5A,FXYD7,NDP,SLCO1C1,NNAT,NPR2,NRGN,NTRK2,CLDN11,SEMA5B,PIK3R1,XRN1,PLEC,FXYD1,SLC25A23,C11orf49,STRN3,NECAB2,SH3KBP1,POU3F2,MED1,PPP2R2B,LRRN3,EPDR1,MAPK10,BCAS3,GON4L,PTCH1,PTPRD,RIPOR1,RAB3A,BEND5,RNF220,RNH1,KIAA0895L,STK32B,EMID1,MEG3,RYR1,CSRNP3,KIF16B,SMARCD3,SNCA,CABCOCO1,KDM4B,FAM219A,MYT1L,FNBP1,SOX11,LHFPL4,NPAS3,SST,SSTR2,LRRC4,APOM,FGD4,ZFR2,SYNE2,C3orf70,ARC,COBL,MCF2L,DNMBP,DMXL2,TEK,TLR4,ANKRD24,TNNT1,NPL,FNDC5,PDIA2,BCL2L13,LAT2,LAMP5,PRDM2,PARP6,ADAMTS9,TMEM163,SLC17A6,RGS7BP,UBE3B,GJC2,NHSL1,IFT88,DPF3,SOCS4,LAS1L,SENP7" Coexpression M17937 Top 100 probe sets contrubuting to the negative side of the 1st principal component; predominantly associated with synovial sarcoma and myxoid/round cell liposarcoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.20E-13 1.39E-09 2.21E-11 2.19E-10 39 74 "SEMA6A,APBA2,CACNA1G,HIP1R,CRLF1,LHX2,COL4A5,COL9A3,KBTBD11,SEZ6L2,EDN3,EFNB3,EMX2,OLFM1,FGFR3,CAP2,B3GAT1,TOX3,ADGRA3,GPD1,GPM6B,WIF1,MDFI,NEFH,NELL1,NNAT,NPTX2,NTRK2,EPB41L4B,PPP1R1A,RET,SHANK2,SOX11,PEG10,TAC1,CUX2,RIMBP2,TRO,ITM2C" Coexpression 18535662-TableS2a Mouse Lymphoma_Wu08_1777genes GeneSigDB 1.96E-13 2.27E-09 3.55E-11 3.53E-10 221 894 "CLK4,ADD3,AP2A2,TAOK1,C1QTNF3,ALCAM,OGT,MYH7B,PHYHD1,API5,APP,CASK,ASGR1,CHID1,ATP1B3,ATP6V0A1,ADAM15,BACH1,BCL2L2,NRP2,BID,SYNJ2,BTK,SGCE,CACNA1G,CACNA1B,CALM1,CAMK2D,CAMK2G,CAST,SPAG9,RUNX1T1,ARHGEF25,CBFA2T2,CDK11B,CDH2,CDO1,FOXN3,CNOT8,CLU,TPP1,ABCG2,DNAJB5,TMEM184B,PICK1,IQCK,SUMF2,COL11A2,MAGED1,CREM,ENTPD4,CRMP1,CLIP3,ARHGEF10,ATRNL1,SIPA1L1,GPSM1,BOC,FGFR1OP2,IP6K1,DBN1,PITPNC1,BLOC1S6,NR1D2,TOM1,GOLT1B,KLHL5,ASB3,ELN,SLC43A2,STX2,ERBB2,NCALD,VPS26C,EXTL2,EZH1,F3,AMZ2,RPS6KC1,RACK1,FCGRT,FDFT1,FECH,FGFR1,BAIAP2,FHL1,FLNC,FLT1,DCTN2,DPYSL4,SORBS1,NPTN,ATP6V1H,ERGIC3,CGREF1,SARAF,ABLIM2,NCKAP1,INPP5K,DHRS4,OS9,GNAS,FERMT2,PRUNE2,GPM6B,RAPGEF4,NR3C1,GSN,MAP4K5,JAK2,METTL21A,KIF2A,KLC1,LAMP2,LIFR,VWA5A,MAT2A,MEST,PPM1L,MMP16,CD200,CCDC80,NRBP2,TAGLN3,MYH6,NAP1L2,NBL1,NFE2L2,DDR2,NUCB1,NUCB2,PCSK2,PENK,SERPINE2,SSH1,RETREG1,PLCD1,PLTP,MAPKAP1,SH3KBP1,PPM1B,PPP3CA,PPP3CC,PRKCZ,EPDR1,RELN,CNNM2,APTX,SYTL2,PTH1R,PTPN13,PYGM,RAB3A,RAD17,PLEKHB2,RALGDS,RDX,TRIM68,PCMTD2,TMEM100,CLIP1,SARS,TNFRSF19,COPZ1,RASA3,PUF60,CHD9,FNDC3A,ARHGEF40,CDK5RAP3,KBTBD4,ABTB1,IFT122,LIMCH1,LMBRD1,GLT8D1,SPP1,ERC1,SPART,MAPK8IP3,STAU1,SEPT8,PHLDB1,SYP,ATP11A,ANKRD12,SMG6,PCDHGA11,OBSL1,FRYL,CYB561A3,TGFBR3,SLC44A1,TMEM9,TJP1,TK2,DDHD1,TPD52L2,TRIO,PDSS1,TMEFF2,UBC,CADM1,TOM1L2,VLDLR,TBC1D15,WIPF1,ATP6V0E2,POLR3H,MEIS3,NT5M,EVI5,STOX2,NAV3,DOCK8,MARCH8,MSRB3,ZDHHC20,FXR1,NETO2,SPATA13" Coexpression M2107 Genes whose expression significantly and positively correlated with oligodendrocyte density in layer VI of BA9 brain region in patients with bipolar disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.86E-13 3.31E-09 5.10E-11 5.06E-10 178 681 "ACADM,ADAR,ADD1,ALCAM,BIN1,APLP1,FAM131A,ATP1A3,ATP2A2,ADGRB2,BCL2L2,NAE1,BAIAP3,CACNA1A,CAMK2B,CAMK2G,CANX,CCK,INA,SYNGR3,ENTPD6,CD81,ARHGEF2,CDH18,MYL6B,CLTA,CLTB,SULT4A1,MAGED1,MYRIP,CRMP1,CLIP3,CRYM,FEZ1,ATRNL1,SLITRK5,PPP1R16B,CX3CR1,KIAA0513,RIMS3,SCRN1,IP6K1,ARMCX2,DCTN1,ELMO1,COPS7A,SV2A,G3BP2,ARNT2,SEC16A,KBTBD11,CHRDL1,DNM1,DPYSL2,ABCC5,OPTN,EFNB3,LINC00599,ENO2,RCAN2,FABP7,CACNG3,TUBB3,TUBB4A,CORO2B,CHST15,FGFR3,FHL1,ATP5PD,UBE2E3,FOXG1,C1orf61,RASL10A,ARFGAP2,NSG2,STAU2,PNMA2,B3GAT1,OGA,GABBR1,CHL1,GPR162,RUNDC3A,GLDC,GLRB,OS9,RAB40B,GNAS,PRRC2B,PRUNE2,PTPRT,GYG1,GABARAPL2,HNRNPK,HPCA,MSL1,IDH3B,ITPKA,KCNF1,MAN2A2,MAOB,MAPT,CD200,PTOV1,LYRM9,NACA,NDUFA5,NELL1,NELL2,NNAT,NPY,NPTX1,NRDC,NUCB1,OMG,DPY19L2P2,PDE2A,SERPINE2,SERPINI1,PKM,PLCD1,FTO,NECAB2,MAPK9,RELN,NDUFS7,PTPRN2,SLC6A15,RGS7,RNH1,RTN1,SARS,TRA2B,PUF60,SCG5,FAM102A,R3HDM2,CLSTN1,SLIT1,SMARCC2,SMARCD3,NMNAT2,CAND2,PEG10,LMO3,SST,NCDN,SEPT8,STX1A,STXBP1,SYT11,SYP,COBL,DDHD2,TAF6,CAMSAP2,EHBP1,WDR7,PHF24,PUM2,BEX4,CABIN1,WBP2,RUNDC3B,RUSC1,TUBB2A,UBC,UCHL1,VSNL1,ATP6V0E2,NDRG4,RNF103,SCG2,WIPF2,NELFE,HNRNPA3,CAMK1G,AP3B2" Coexpression 15888489-Table1 Mouse Brain_Chung05_134genes GeneSigDB 4.12E-13 4.77E-09 7.22E-11 7.17E-10 47 103 "ALCAM,DOC2A,AQP4,ATP1A2,NRP2,BAIAP3,CALB1,CALB2,CBLN1,CCK,CDH2,RAB3C,NECTIN3,BRINP1,GSDME,NTM,CALN1,PLXNC1,TENM1,CDHR1,CEND1,FGF1,FGFR3,MPP6,FAM184B,GAD1,GHR,GRIN2C,IGF1,LIX1,MYH7,FXYD6,NEFM,PPP2R5C,PTPRZ1,RASGRF1,RNASEL,SATB1,SOX6,SLC6A1,SORCS3,SPP1,EHBP1,CADM1,RPRM,KCNAB1,SLC17A6" Coexpression M7562 Genes up-regulated in CD11b+ cells from BALB/c mice: spleen versus bone marrow. MSigDB C7: Immunologic Signatures (v6.0) 4.59E-13 5.31E-09 7.93E-11 7.88E-10 72 198 "RNF157,GPRASP2,LRCH2,ALS2,ATP1A3,ST3GAL5,MTMR3,DDR1,INA,TIGD7,MAP4K4,ARMC8,ENTPD4,NCOR2,PHYHIP,KIAA0753,FAM57B,RCAN1,FAM78B,ST8SIA3,PHC2,ENO2,EXTL2,ARMCX1,PTK2B,AMOTL2,ATP6V1H,BRSK1,ABLIM2,ZNF512,CSDC2,CCDC184,STMN2,RNF165,SMAP1,ATCAY,EID2B,IFI16,CHIC1,CD200,PTOV1,NCAM1,PALM,GPR85,GDAP1L1,SLC26A11,PTCH1,TTC13,RASGRF1,SLC6A15,SEC61A2,ZNF354C,CNKSR2,SIRT2,MAST1,SMARCE1,USP33,PDZD2,CDK19,RAP1GAP2,NACAD,STXBP1,KAZN,CLASP1,SYNE1,FAM155A,ZNF70,REEP1,ZNF177,SCG2,PAK5,CBLN2" Coexpression 16288009-SuppTable2 Human StemCell_Moreno05_297genes GeneSigDB 6.47E-13 7.48E-09 1.10E-10 1.09E-09 88 266 "SLC12A5,BBOX1,PLA2G4C,ASCL1,ATP1B3,ATP2A2,ATP2B1,CADM3,ADAM23,ADGRB2,BLM,CALM1,HIP1R,CDH2,DCLK1,CLGN,FADS2,CNN3,IQCK,CABP1,COL4A5,NECTIN3,CREM,CLIP3,LRIG1,VCAN,ZNF804A,MFAP3L,SPOCK3,RCAN1,EFNB3,BSCL2,ENO2,RCAN2,EPS8,ETV1,F3,ATP8A1,OLFM1,FGFR1,UBE2E3,CSPG5,FUT9,MTHFD2,SYT17,HTATSF1,GP1BB,HLF,IGSF1,BRINP3,KCNK3,KIF5C,MAOB,CD200,ADAM22,NBL1,NEUROD1,NNAT,NPTX2,PCMT1,CDK18,LRRN3,PTN,MEG3,SELL,SH3GL3,NLGN1,ABLIM3,SLC8A2,SLC22A4,SMARCD3,SNCB,FAIM2,NFASC,COLGALT2,NACAD,NCDN,AJAP1,ASTN2,ADGRL3,THBS4,TIAM1,SEZ6L,RUNDC3B,AMOT,VSNL1,TRIM16L,PAK5" Coexpression M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.09E-12 1.26E-08 1.82E-10 1.81E-09 124 430 "ABHD6,NCKAP5,FAM43B,TMEM132B,NLGN4X,KLHL13,NR0B1,ALK,TRMT9B,DGKD,CACHD1,LRRC4C,PPFIA3,IGDCC4,PLA2G4C,ATP1A1,ALDH7A1,GYG2,C5,KALRN,LDB2,MYOM2,SYNPR,SLIT2,KIAA1549L,ARHGEF6,AKAP7,CREM,HDAC9,DAPK1,BRINP1,SV2B,FAM107B,DLG2,DMD,EDNRA,EPHB1,FCGRT,HVCN1,CSPG5,AP4B1,GFRA2,FREM1,PCDH17,MAP7D2,GPD2,GPR17,GPR37,GRIA2,GRIK2,LINC00839,LINGO1,TOX2,PADI2,IGF1,SCIN,ITGAM,JAK1,OLFM3,KCNK3,KIT,LMO2,MAPT,TM6SF1,MEIS1,POC1B,SAMD5,NELL2,NKX2-2,NOS1,NPTX2,NRCAM,OPCML,PBX1,PCDH9,PCSK2,CYTL1,CDK14,PIK3R1,TRHDE,FAT3,LRRN3,PRKCB,RELN,PTPN13,MARCH1,ATG16L1,FAT4,NUDT11,MRAP2,PRR5L,STK32B,SEMA6D,CSRNP3,LRFN5,SEC14L1,SOX6,SH3GL3,NTNG1,ST6GAL1,SLC15A2,EFHD1,SOX2,FNBP1,SPP1,ZC3H13,LMO3,CLSTN2,COLGALT2,TMEM178B,TCF4,TCF12,TNNT1,TMEFF2,DNAJC12,SLAIN1,TSPAN11,ZNF711,ZBTB16,REEP1,LRP8,STMN4,SLC17A7,SPATA13" Coexpression M14791 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.39E-12 1.61E-08 2.30E-10 2.29E-09 93 291 "XKR4,ADCY2,TMCC3,SORCS1,NLGN4X,PCDH19,DPP10,ANK2,ASPA,ATP1A2,SLC4A4,BCHE,CA4,VSTM2A,USP2,CHGA,CHGB,JAM2,NRXN1,CLU,ABCG2,ABI3BP,MFSD4A,CP,AKAP12,HAPLN1,SV2B,CHRDL1,EDIL3,EDN3,ENPP6,TLR7,ABCA8,EFEMP1,C2orf88,WASF3,GCNT2,GHR,LYVE1,GPM6B,NR3C1,FAM107A,IGF1,IL6R,BRINP3,INSM1,KIF5C,L1CAM,LIFR,DPP10-AS1,ZNF667-AS1,MEIS1,MT1M,RSPO2,NEXMIF,NAP1L2,NAP1L3,NEUROD1,NPY,PCDH9,TMOD2,CYTL1,FXYD1,PLP1,PRKCB,CNNM2,LAMA1,GDPD2,PTN,TMEM255A,BEND5,PRIMA1,TMEM100,GLDN,LRRK2,RTN1,SEMA6D,SCN7A,DOCK10,SLC22A4,SOX10,MIR100HG,SST,EPB41L3,WSCD1,TNS1,SYNPO2,RUNDC3B,ANO5,FLRT2,FMN2,SCG2,FAM13C" Coexpression 16166618-SuppTable4 Mouse Lung_not_cancer_Woodruff05_2371genes GeneSigDB 1.41E-12 1.64E-08 2.30E-10 2.29E-09 333 1505 "CPNE2,ABR,ABHD6,AS3MT,ACTN1,FMNL2,TMCC3,GRAMD1B,MTA3,OSBPL8,ALCAM,BCAR3,ABCD2,MARCH4,BIN1,OGT,FGD2,LCORL,ANXA7,APBB2,GAS7,BCAS1,CPNE5,PDXK,ARRB1,ARRB2,PDE8B,ASPH,NCOA1,CHID1,ATM,ATP2B1,DPY19L3,ATP6V0A1,ADAM23,BID,DST,ST3GAL5,C1QC,RAB29,FOXK1,CACNA1D,CACNB4,KALRN,CAMK2G,VSTM2A,CH25H,PRC1,METTL6,FMNL3,USP2,MTMR7,CD86,SCARB1,CD38,ARHGEF2,REPS2,CDC25B,LRRFIP1,CDO1,CCPG1,CFL2,SOCS6,MS4A7,B4GALT6,FAM189A2,TJP2,CNN3,AKAP7,ARMC8,FAM149A,AKAP5,MAGED1,IFFO1,CREM,RNF14,ANKRD44,NCOR2,GDA,ABCG1,CSF1,TENM4,FEZ2,CSNK1E,OSBPL3,ATRNL1,SIPA1L1,CHD5,SOCS5,PDE4DIP,PNPLA8,GREB1,ST18,USP6NL,DOCK4,HDAC9,RIPOR2,LONRF1,RIMS3,DGKG,DAPK1,DBI,GIT2,ARMCX2,GSDME,DDX46,POM121,RHOBTB1,RABGAP1L,FAM107B,ARNT2,DLG3,DMD,CDON,RCAN1,DUSP9,E2F5,TSPAN5,RASGRP1,FRY,OPTN,YAF2,SH3GLB1,EBI3,PLXNC1,RASA4,LPAR6,CALCRL,DCTN4,PLEKHO1,ENO2,ENPP6,EPS8,SPEG,ETV1,RCSD1,F5,FAM198B,ACSL4,PTK2B,CORO2B,CHST15,FCGRT,TESK2,GORAB,FGF11,SPSB4,FGFR1,BAIAP2,FGR,PCYOX1,EVL,FLT1,FOLR2,TACC2,SORBS1,SMC2,SPECC1,HVCN1,AK8,ATP6V1H,FYB1,CAB39,AHCYL1,B4GALNT1,RAPGEF6,IQGAP2,MTHFD2,SEPT9,ACSS1,GCNT2,SESN1,GGT5,HPGDS,DBF4,GLUL,GPT2,PRRC2B,LPAR4,EML4,DIDO1,RFFL,KIF3A,MUM1,IRAK3,RASSF8,HNMT,IGF1,RBPJ,DIPK1A,TUBB2B,ITGAM,KCNN3,KIT,STXBP5,L1CAM,LAMP2,LIFR,LIMS1,HECTD2,SMAD1,PIK3AP1,GPR155,MATK,MATN2,IL17D,LDLRAD3,MEIS1,AFDN,MN1,ADAM22,MSR1,MYO5A,MYO6,NAP1L1,P2RY13,NFIA,NFIX,NPY,NUCB2,ODF2,OGDH,OLR1,P2RY1,TREM2,CDK18,PDE2A,GNG2,PFKFB4,CDK14,ANLN,SNX10,PMP22,PILRA,SH3KBP1,PRKAR1B,PRKCB,GRAMD1C,SNRK,MTMR10,PTK2,PTPRO,FAM120C,NKAIN1,PID1,ZDHHC14,CCDC82,TMEM206,PRR5L,ACER3,WLS,SARS,SEMA6D,SATB1,ATXN1,SELL,SFPQ,MRAS,HSPA4L,ITSN1,PPP1R9A,DOCK10,CHD9,ST6GAL1,BTBD3,LIMS2,SLC6A8,SLC11A1,SLC12A2,SLC15A2,SLC22A4,SMARCC2,IFT122,KIF13A,PALLD,TMCC1,FNBP1,SP4,UHRF1BP1L,MYCBP2,SPP1,BEX1,ARHGAP26,DBNDD2,RAP1GAP2,SPART,SRPK2,RGL1,STAC2,SULF2,SEPT3,FAM168A,ZC3H4,SYNE2,SYN1,SLC37A2,SEMA4A,MCF2L,ADGRL3,EHBP1,DMXL2,TCF7L2,PSD3,ARHGAP9,AHCYL2,SIK3,CYB561A3,ENHO,TIAM1,BHLHB9,LRRC8A,TMPO,TNFRSF1B,PRRT1,TNS1,AMACR,TTC3,TUBB2A,CADM1,FLRT2,VAV2,MICAL1,LAT2,AGMO,CELF4,AMZ1,SPIRE1,LRP8,TUBA1A,NAV2,RTN4,PHTF2,ZDHHC20" Coexpression 19605494-TableS3 Mouse Skin_Driskell09_685genes GeneSigDB 3.67E-12 4.24E-08 5.89E-10 5.85E-09 124 437 "ASIC2,ACTN1,INTS2,SEMA6A,ANK3,SEMA7A,PPP4R4,TMEFF1,ASPH,PTCH2,ATP1A2,CADM3,DPY19L3,KSR1,DST,CACNA1G,FMNL3,CD38,JAM2,ABCG2,SLC25A27,CP,HAPLN1,ANKRD44,GDA,CRYM,GALNT9,PLXNA4,PPP1R16B,GPSM1,DOCK4,HDAC9,RIPOR2,SIRPA,SACS,CCDC3,DLX1,DMD,HEYL,TMTC1,FRY,CALCRL,EPS8,DENND4A,MRVI1,PTK2B,ST3GAL6,FLT1,PHYHIPL,GABBR1,GALNT15,GCNT2,LYVE1,BRD8,RND1,MCHR1,HES5,TUBB2B,KIF5C,L1CAM,TTYH2,LMO2,LSAMP,SRSF12,TAGLN3,HNRNPM,SLCO1C1,OPHN1,PIK3R1,NXPH1,PCDHB17P,PPP3CC,SKOR1,GDPD1,PTPRB,PTPRG,RASGRF2,TRIM68,SLC25A36,TMEM206,LRFN5,SLC30A10,MRAS,PPP1R9A,CLSTN1,ABLIM3,SLC14A1,SLC22A4,TET1,CXXC4,MBD5,KIF13A,SNRPN,KIF21B,SOX11,UNC5B,CDK19,NPAS3,LMO3,SYNE2,PLCB1,SYP,ANKRD12,SYNE1,DOCK9,ARHGAP9,FRYL,TEK,TGFBR3,TIAM1,TIE1,TNFRSF1B,FNDC5,CADM1,UCHL1,REEP1,DPYSL5,ANKS1B,SLC38A1,SEMA3B,PCDH15,FAM13C,FZD3,DOCK8" Coexpression 19605494-TableS1 Mouse Skin_Driskell09_1322genes GeneSigDB 3.83E-12 4.43E-08 6.08E-10 6.03E-09 195 786 "TKTL1,ACTN1,GALNT16,TMCC3,RNF150,KLHL13,OSBPL6,SORCS2,PCDH10,GOLGA7B,GPRASP2,APOC1,LGR5,CDC14B,ARNTL,PDE8B,ASPH,ZSCAN18,SLC4A4,BMP7,BTK,CACNA1B,CACNA2D1,CBLN1,CDH2,B4GALT6,JAM2,NDST3,LHX2,FAM19A5,CNTFR,CLOCK,CREB5,GDA,CSF1,RGS6,LRIG1,PLCH2,PHACTR3,PLXNA4,PITPNM3,ERC2,CTNND2,CYBB,GPRASP1,ARHGAP24,LONRF1,SIRPA,DCT,KBTBD11,CHRDL1,NR1D2,DOCK2,DSCAM,ABCC9,EBF1,EDN3,EDNRB,CNNM1,TMTC1,EGFR,PLXNC1,RASA4,CERCAM,ELN,EPHB1,NCALD,PIPOX,NRN1,F3,EFEMP1,MED12L,FGFR1,CAP2,FLT1,PSD2,SORBS1,FAM49B,ST6GALNAC3,FYB1,STARD10,WASF3,GCNT2,GFRA1,GFRA2,FREM1,PCDH17,CSDC2,HPGDS,MCHR1,STMN2,GRIK3,CIT,SOX21,GUCY1A1,TOX2,FRMD3,NCKAP1L,HLF,HSF2,JAK2,METTL21A,KCNJ3,KIF5A,KIT,LAMA2,CAMK2N2,VWA5A,ASPRV1,NAT8L,CD200,MSI1,FXYD6,NAP1L3,NBL1,NDP,NFIA,VWA2,NOVA1,NPTX2,NTRK2,NTRK3,OPCML,OXTR,CNTN3,PDE3A,PDE1B,PDGFRA,ENPP2,PENK,SLC25A23,RC3H2,PRRX1,PILRA,NXPH1,PPP2R2C,PRKAR1B,PRKCB,SYTL2,PID1,TMEM255A,FAM184A,GAL3ST4,RET,RGS4,WLS,SCN3A,ELMOD1,SELL,DOCK10,SLA,PREX2,SLC15A2,KIF13A,SNRPN,SOX11,CDK19,CLSTN2,SAMSN1,THSD1,SS18,STAC2,AJAP1,ARHGEF9,SYN2,COBL,ANKRD28,ASTN2,TAC1,DMXL2,PCDHB9,PCDHB3,TNS2,ARHGAP9,TEX15,HEY1,HEY2,DAAM2,TNNT1,TRPC1,TMEFF2,RPRM,AMOT,FLRT2,FAM181B,ZIC1,ZBTB16,CADM2,DNALI1,PLSCR4,RGS7BP,FZD3,DOCK8,NETO2,CPNE4" Coexpression M2010 Genes with high-CpG-density promoters (HCP) bearing the bivalent histone H3 trimethylation mark at K4 and K27 (H3K4me3 and H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.04E-12 4.68E-08 6.32E-10 6.28E-09 73 210 "CCDC85A,ADORA1,UNC5A,SLC24A4,DISP3,SEMA7A,AMER3,CDK5R2,CBLN1,INA,NOG,KIAA1549L,SLC24A2,MYRIP,MFSD4A,TENM4,RGS6,PLXNA4,AK5,CELSR3,CDHR1,FGF11,FOXF2,FLT1,ABLIM2,GABRA4,GAD1,INSM2,GNAL,ADAMTS8,PTPN5,NXPH3,GPR45,FRMD5,HMX1,KNDC1,KCNA1,KCNJ4,KCNK1,KCNMA1,KIF5C,STK32C,RSPO2,NEFM,GPR88,PCDH8,PCSK2,PLTP,RASGEF1B,RELN,LAMA1,PTPRN2,RASGRF1,SLC6A15,RET,KLHDC8A,SATB1,SLC30A10,NTNG1,SOX1,NMNAT2,TACR1,CHST8,CDH22,CSMD1,PRMT8,TUB,VGF,KCNK12,ELFN1,WNK2,AP3B2,ST8SIA2" Coexpression M1935 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation marks at k4 (H3K4me3) and K27 ((H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.15E-12 4.80E-08 6.40E-10 6.36E-09 56 142 "CCDC85A,ADORA1,UNC5A,SLC24A4,DISP3,CBLN1,INA,KIAA1549L,SLC24A2,TENM4,PLXNA4,AK5,CELSR3,EPB41L1,FGF11,FLT1,ABLIM2,MEGF11,GAD1,GNAL,ADAMTS8,GRM8,PTPN5,ATOH8,GPR45,FRMD5,KNDC1,KCNJ4,KCNMA1,KIF5C,LMO2,STK32C,RSPO2,NEFM,GPR88,PCDH8,PDE4A,PLTP,RASGEF1B,RELN,KHDRBS2,KLHDC8A,EPHA10,SATB1,ELMOD1,NTNG1,SOX1,NMNAT2,CHST8,CDH22,CSMD1,TUB,VGF,ELFN1,WNK2,ST8SIA2" Coexpression 19286929-SuppTable2a Mouse Lung_Rangasamy09_168genes GeneSigDB 4.71E-12 5.44E-08 7.16E-10 7.11E-09 59 154 "CDC7,PCDH10,APC,DOCK11,ADAM23,NRP2,CCNH,CDC25B,CDH2,CDH8,CDH10,SLIT2,NRXN3,ARMC8,NECTIN3,CNTNAP2,CDON,DOCK2,EDIL3,PCDH17,GP1BB,NEGR1,DOCK7,ITGAM,VWA5A,LSAMP,NCAM2,NELL1,NRCAM,OPCML,PAK3,PCDH9,PCDH18,SEPT4,PCDHB17P,PPP3CA,FAT4,RBBP8,SELL,KIF16B,DOCK10,NLGN1,RADIL,CDK19,RBM26,CLASP2,SEPT8,SEPT3,PLCB1,PCDHGA11,PCDHB9,TEK,RGMB,ZMYND8,PCDH20,SMARCAD1,CADM2,PCDH15,SSPN" Coexpression M4305 Genes up-regulated in comparison of naive vs effector CD8 T cells (3.5 days postinfection). MSigDB C7: Immunologic Signatures (v6.0) 7.71E-12 8.92E-08 1.15E-09 1.14E-08 70 200 "FAM43B,ADCY5,ADD2,KIAA1211,PTCHD1,PLA2G6,SPARCL1,DACT3,PTCH2,CPNE6,SLC35F1,CSF1R,AIF1L,SV2B,SV2A,SLC29A4,DRP2,FAM78B,ELAVL2,ELAVL4,SRPK3,TUBB4A,SCML2,CORO2B,DPYSL4,FUT9,TMEM151A,TMEM8B,GPR162,CSDC2,C1QL1,GPR12,CCDC184,GPR26,PCLO,IGSF21,HPCA,LIX1,KCNA2,KCND2,MOBP,MYH6,NBL1,NPY,PLCL1,PNMA3,NXPH1,VSTM2L,EPDR1,PTPRN,TMEM200C,SH3GL3,SLC2A5,EPN2,SLC8A1,ARHGEF40,KIF1B,RHBDL3,SYN1,SYP,PCDHB7,ZFPM2,HHIP,PARD3,PRMT8,TTC3,FSTL5,STMN4,ADAMTS9,IFT88" Coexpression M16651 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to normal thyroid tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.73E-12 8.94E-08 1.15E-09 1.14E-08 197 802 "ABAT,TMCC3,ADD1,ADD3,PLEKHH1,ALAD,GPRASP2,APBB2,EPB41L5,NT5C3B,CACHD1,CDK10,ARHGAP5,CDK13,ZSCAN18,ATP1A1,SLC4A4,ZNF599,CFLAR,PROM1,KSR1,SYNJ2,ARHGEF7,MTMR3,DDR1,CACNA2D1,CAPN3,CLDN10,FMNL3,LRRFIP1,MAGI1,SRSF11,SLIT2,CLU,FBXO7,QKI,HECTD1,ABCG1,LRIG1,CST3,CTNND1,PPP6R2,BOC,GPRASP1,TCAF1,DCAF8,CENPL,YTHDC1,ZEB2,MAGI2,SMG7,DMD,NR1D2,CDON,DTNA,ECM2,WDPCP,TSPAN5,EDNRB,HIPK3,FCF1,TMTC1,SIDT2,FAM13A,KMT5B,ABI2,RASA4,ERBB2,MRVI1,ABCA8,WAC,SH3YL1,ATP8A1,FDFT1,TMEM164,PRKAG2,PCYOX1,ZBED3,PDLIM5,ARFGAP2,ERAP1,WASF3,GATM,SESN1,GLUL,ZNF638,RAB40B,GNAL,GNAS,LNX1,GOLGB1,CROCCP2,RFFL,GSN,AP4S1,MGC16275,LINC00667,ST7-AS1,USP54,IL11RA,LIFR,VWA5A,SMAD9,MARK3,MATN2,MBNL1,MBP,MDM4,MIA2,AFDN,CCDC80,MXI1,LYRM9,MYO9A,NDUFA5,NF1,NFIA,PDCD2,PRTG,ENPP2,PFKFB2,PIK3C2A,ZFYVE21,EPB41L4B,PPP3CB,KANSL1,PROX1,VPS13C,GON4L,SNRK,MTMR10,PTPN13,PTPRB,PTPRG,PID1,RAP1GAP,ZNF493,HKR1,BSDC1,MSANTD2,RPL15,FAM161B,CLIP1,ZNF331,ATXN1,SOX6,CASC3,GALNT10,SUPT20H,SGK1,ASAP3,CHD9,CCDC92,SHANK2,ATF7IP,CPEB4,SMARCE1,LIMCH1,KDM4B,FNBP1,SPP1,TEX2,TAB2,POGZ,ITPRID2,ERBIN,ST5,KANK1,FGD4,SYNE2,TMEM150C,ANKRD28,WWC1,TCF4,WDR7,NSD1,AHCYL2,SIK3,DICER1,TGFBR3,BEX4,TNS1,C9orf85,PPIL6,SSBP2,HIRA,UBTF,TOM1L2,LRP8,TMEM178A,EPM2A,FZD3,RNF170,TTC7A,KLHDC1,RNF146,SPATA13" Coexpression M1999 The 'adult tissue stem' module: genes coordinately up-regulated in a compendium of adult tissue stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.99E-12 9.25E-08 1.17E-09 1.16E-08 181 721 "ACTN1,NDRG2,ADCY6,SNX30,ADRB2,OSBPL1A,SORCS2,TXNDC16,ALCAM,AMPD3,ANK3,APP,LGR5,CAPRIN2,ASTN1,ATP2A2,BACH1,MPDZ,FGF17,DST,SGCE,CACNA2D1,CAMK2B,MAP7,USP2,CDH2,ZMYM4,LRRFIP1,LARGE1,CACNA2D2,ADGRG1,ABCG2,CNN3,CNTN1,COL9A3,MAGED1,ZNF521,ABCG1,CSF2RA,ARHGEF10,MYADM,ARHGAP32,DGKG,ARMCX2,CEP170,MAGI2,DLG3,DMD,SH3GLB1,CELSR3,EBI3,EIF1,RCAN2,EPHA5,EPS8,F3,DLC1,SEC24B,SLC9B2,FGF1,FHL1,EVL,NBEA,RASL10A,KHDRBS3,NSG2,SARAF,TBR1,FYN,DKK3,GABBR1,GABRA3,GABRG1,ZMYND11,NCKAP1,GATM,SESN1,GLUL,FERMT2,ADGRA3,PCLO,GRIA2,GRID1,GRIK1,PRDM5,HLF,ELOVL5,SYNPO,DOCK7,JAK1,KCNA1,KCNA2,KCND2,KCNK2,KCNMA1,KIT,KTN1,L1CAM,LAMA2,LMO2,SYTL4,SMAD1,MAP2,MATN2,MEIS1,KITLG,MITF,MMP17,CD200,PTOV1,TAGLN3,MYCN,MYH3,NAP1L3,NCAM1,NCAM2,NFIX,NRCAM,PBX1,PDE2A,SNX10,RETREG1,PMP22,RC3H2,EPB41L4B,PACSIN1,PRKACB,PKIA,PRKCB,RELN,PTN,PYGM,SLC6A15,RGS4,ROBO1,SOX6,SCG5,ZFP30,ITSN1,PPP1R9A,NBPF1,SLC8A1,SLC12A2,ZFP1,GKAP1,LIMCH1,CAND2,BEX1,DBNDD2,THSD1,MPRIP,STXBP1,SYT4,TAC1,TAL1,PDLIM2,TCF4,ZFP90,PCDHB15,SIK3,TEK,AKTIP,THBS4,TIE1,NACC2,TK2,LRRC8A,BEX4,TP53BP1,TPM1,SSBP2,TTC3,TTPA,CADM1,VLDLR,ZNF23,PMEPA1,ITM2C,PHTF2,ACTR3B,FRMD6" Coexpression 16293578-SuppTable2 Human StemCell_Cai06_1370genes GeneSigDB 8.29E-12 9.58E-08 1.20E-09 1.19E-08 271 1190 "CPNE2,ASIC1,NDRG2,ADORA1,NLGN4X,MTA3,PCDH19,NME5,SRPX,SYT13,PDZD4,BIN1,LRCH2,USP28,PKP4,CNTNAP1,APBB1,APLP1,CCDC74A,RASL11B,RNF182,ADAM23,ST3GAL5,CA4,CA12,CALB2,CAST,MAP7,CLDN10,SEPT7,DCLK1,CRLF1,CFL2,FOXN3,CHGA,CHN1,RAB3C,SLIT2,TMEM59L,RAB26,CCDC151,CNTFR,CNTN1,IQCK,PCYT1B,COL4A5,COL9A2,SLC4A8,MAGED1,ZNF521,IGDCC3,CPS1,PNKD,CLIP3,CRYM,LRIG1,CST3,CALY,CTH,CTNND2,DCAF4,BOC,LONRF1,PITPNC1,GSDME,RHOBTB1,SRGAP3,RABGAP1L,FAM107B,CCDC3,ARNT2,DMD,DMPK,CD99L2,RPS6KL1,SLC29A4,FAM57B,RCAN1,DUSP9,ABCC9,TSPAN5,PHC2,EFNB3,MBNL2,CERCAM,RGS17,LRRC23,ERBB2,NCALD,APC2,RRAGB,FABP7,CACNG2,ZIC4,OLFM1,POLR1B,SPSB4,FGF13,FGFR3,MAD2L2,FHL1,SCARA3,SEMA4D,TMEM175,SORBS1,TPK1,B3GAT1,TMEM151A,GABRA5,GABRB3,GAD1,JPH4,SALL3,TMEM8B,MTHFD2,SYT17,GART,GATM,GPR162,FREM1,MALT1,RNPS1,GLDC,GLS,GNG4,GP1BB,GPM6A,LPAR4,TMEM121B,STMN2,DIDO1,GSN,LINGO1,PSIP1,ATOH8,ICA1,NKD1,ZIC5,IL11RA,INPP1,KCNMA1,KCNQ2,KIFC3,VWA5A,MATN2,MDFI,IL17D,SCAMP5,CPNE9,TAGLN3,LAYN,FXYD6,NCAM1,NEFM,NNAT,NPY,DDR2,NUCB2,ODF2,OLR1,PALM,PAX6,PCSK5,PDCD2,ENPP2,CAMKV,PIK3CD,PIK3R1,JAKMIP1,PLTP,PMP22,NECAB2,EPB41L4B,PACSIN1,PPM1B,LRRN3,PPP3CC,NKAIN4,PKIA,PRKCB,MAPK3,PRODH,PRPH,MASP1,ANKHD1,PTN,TMEM145,NKAIN1,PID1,FAM184A,FEZF2,SLC6A15,ZMAT4,PRRT2,MORC4,RGS3,RGS4,BAALC,RIMKLA,HSD11B1L,WLS,KCNIP1,CCDC112,LRFN5,TNFRSF19,IL17RB,SH3GL2,FNDC3A,CCDC92,LIMS2,SEPHS1,EFHD1,TET1,CXXC4,ABTB1,SMARCD3,RCOR3,SNCA,SNRPN,PALLD,ZCCHC24,SOX10,TEX2,RAP1GAP2,TAB2,LARP4,FCHO1,RGL1,SULF2,SYT11,VPS13A,COBL,TAC3,TACC1,SEMA4A,UNC5D,ADGRL3,SYNE1,TEK,SIRT1,LEFTY2,GALNT17,ENHO,HEY1,ICAM5,DAAM2,TPM2,FNDC5,TTC3,CADM1,AMOT,SLAIN1,FLRT2,VSNL1,WIPF1,KCNK12,ZIC2,ZIC3,TCEAL7,PROCA1,LRP8,RGMA,GDPD5,ADAMTS9,PCBP4,MPPE1,ST7,UBE3B,PAK5,FRMD6,AP3B2" Coexpression M10332 Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-11 1.32E-07 1.64E-09 1.62E-08 33 63 "BIN1,APBB1,DGKZ,ATP1A2,ATP2A2,ARHGEF25,CCK,CLTB,EEF1A2,ENO2,PTK2B,GK,GPD1,GRIA1,GRIA2,KCNMA1,NPTX1,NRGN,PKM,PPP3CA,PRKCB,MAPK3,PYGM,RAB3A,RASGRF1,FBXW7,SH3GL2,SOX10,STXBP1,SYP,SYT1,NTSR2,KCNAB1" Coexpression M12921 Genes up-regulated in brain from patients with Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.24E-11 1.44E-07 1.75E-09 1.74E-08 362 1690 "SERPINA3,RBM10,ARID1A,ADARB2,ADCY2,ADD3,BRAP,AP1B1,MTUS1,AK2,PLA2G6,SPOP,SRPX,AMPD3,BIN1,EP400,PPFIA1,APOC1,APP,LGR5,AQP6,CDK10,SEMA4G,CASK,CDK13,ASCL1,ZBTB10,NUMB,SLC4A4,MYOM1,AZGP1,RGS9,NRP2,CFLAR,DST,GYG2,CACNA1G,C5,OSGIN2,MYRF,LDLRAD4,BTRC,CFAP410,CACNA1A,DDR1,CAPN3,CAST,CH25H,HIP1R,SPAG9,MAP7,RGN,CD86,SCARB1,CDC25B,ZMYM4,LRRFIP1,LARGE1,CRLF1,ADGRG1,FOXN3,TAOK2,NRXN2,CLU,FAM189A2,TJP2,QKI,NIPBL,HOMER3,PICK1,ARMC8,WHRN,COL4A5,SLC4A7,GAL3ST1,AHCTF1,CP,CRHBP,NCOR2,AATK,CSF1,SEC24C,FEZ2,FEZ1,ARHGEF10,CSNK1E,VCAN,PUM1,RIMS2,ST18,HDAC4,ZNF337,TBC1D5,DGKG,DAPK3,PITPNC1,HEPH,FBXL5,MED24,DMD,DMPK,USP3,DTNA,ECM2,TOM1,DUSP9,E2F5,USH1C,TSPAN5,EDNRA,PHC2,SGK2,EEF1D,EGFR,EIF5,IRAK4,ING4,C3orf18,USPL1,TUBD1,COQ7,RASGRP2,EPS8,ERBB4,IGSF6,EFS,RASL12,EFEMP1,FDFT1,FGF1,POLR1B,FGFR1,FGFR3,AMOTL2,FOXO3,FLNC,NOP56,SORBS1,ARFGAP2,FYN,STAG2,DKK3,ZNF274,IQGAP2,ERAP1,SEPT9,INPP5K,NEU3,TUBA8,SRCAP,GDF9,GPR162,GFAP,USP19,PCDH17,MALT1,GJB1,DBF4,GLI2,STARD3,OS9,KCNMB4,GOLGB1,ADGRA3,GPM6B,LILRA2,ADAP1,LPAR4,GRB10,CACFD1,CLASRP,GSTM5,IL1RAPL1,GSTT2,FICD,FAM107A,PTGDR2,PACSIN2,MAN1B1,BACH2,HAPLN2,HMGCL,HSP90AA1,IFI16,RBPJ,TJAP1,IL6R,IL6ST,INPP1,ITGA7,ITPKB,KCNA6,KCNN3,KTN1,LAMA2,LIFR,LSS,SMAD1,MAN2A2,MAP4,MARK3,MAT2A,MATN2,MBP,KITLG,MID1,MITF,AFF1,MMP16,MXI1,MYBPC1,MYCN,MYO6,HNRNPM,NAP1L1,NCAM1,NEK1,NME4,NTRK3,DDR2,NUMA1,OGDH,OGG1,OPHN1,PAH,KCNK10,PAX6,PC,PCDH9,PCSK5,PDE3A,PDE4D,PFKFB3,SSH1,PKD1,PLCL1,PLEC,SMOX,CDIP1,RC3H2,PRRX1,ING3,PILRA,FA2H,MED1,PPM1B,PPP1R1A,PTPA,PROX1,MASP1,APTX,SNRK,PTCH1,PTH1R,PTPRH,RALGDS,ARID4A,RBBP6,TRIM68,RFX4,RGS12,PBRM1,ZFHX4,RPL38,EMID1,RXRG,SAFB,MAPK12,SELL,CASC3,GALNT10,MRAS,SUPT20H,SGK1,SH3BP2,ITSN1,PPP1R9A,SH3GL3,ASAP3,SHMT2,FBXO11,BCAN,ST8SIA1,SLC1A7,SLC6A8,SEPHS1,RAB3GAP1,SIRT2,SLC11A1,SLC14A1,ARFGAP1,SMARCC2,PALLD,USP33,SOX2,FNBP1,KDM3A,ZHX3,ARHGAP26,NPAS3,NFASC,SRPK2,TROVE2,POGZ,COLGALT2,ITPRID2,LARP4,ERBIN,ST5,STAU1,DIP2A,MLC1,JMJD6,ZC3H4,TACC1,FAM208A,PDLIM2,TBL1X,TCF7,TCF7L2,USP22,TF,DICER1,TGFBR3,THRA,DAAM2,R3HDM1,PARD3,KAT6B,TPD52,TPD52L2,PDSS1,TRPS1,USP1,BEST1,CLIP2,LAT2,WRN,ZIC1,ZNF24,ZNF32,ZBTB16,ZNF195,SYNC,UPF3A,WNK1,PRDM2,SLC38A1,CSDE1,TUBA1A,ADAMTS9,SEMA3B,NAV2,WIPF2,C12orf4,PDSS2,UBE3B,KAT6A,NUP214,SSPN,FXR1,DPF3" Coexpression 15720813-Table2 Human Brain_Hoelzinger05_59genes GeneSigDB 1.36E-11 1.57E-07 1.90E-09 1.88E-08 30 54 "BCL2L2,ARHGEF7,INA,CHN1,CRYM,KIAA0513,EFNB3,EGFR,RCAN2,DKK3,GABRG2,GPR19,HLF,KCNK1,MEF2C,TAGLN3,NELL2,NPTX1,NUCB1,OPCML,PDE1A,ENPP2,SERPINI1,KLK6,PTPRN2,RGS7,SMARCC2,BEX1,NEK4,FIP1L1" Coexpression M14127 Genes up-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.83E-11 2.12E-07 2.53E-09 2.51E-08 127 461 "ABAT,C3orf14,TKTL1,ALCAM,BIN1,APLP1,CDC14B,ALDH4A1,CACNA1G,WASF1,BAIAP3,CALM1,SPAG9,CCK,SLC16A4,LHX2,NRXN1,SLC4A8,AKAP12,MICAL2,NCAN,CNTNAP2,DZIP3,CTH,KIAA0513,DBN1,ARMCX2,AASS,TENM1,RASGRP2,CDKL3,TUBB3,TUBB4A,TAOK3,FER,KIAA1109,FGFR1,FGFR3,BAIAP2,FHL1,FOXG1,SORBS1,PDLIM5,CGREF1,CSPG5,GLDC,TOX3,GLUL,GPM6A,PCLO,GSN,RNFT2,HBA1,ACOT7,HSD17B1,TUBB2B,ITGA7,KCNN2,KHK,KIF5C,L1CAM,LIFR,MAPT,MEF2C,MYCN,NAP1L3,NCAM1,NFYA,NPTX2,NRGN,PCDH9,CDK18,ENPP2,PFKFB3,ABCB1,SERPINE2,SERPINI1,PIK3CD,GPSM2,PLEC,PLXNB3,SEPT4,PRKCB,PRPH,PTK2,RADX,NUDT11,RPS6KA2,RPS20,SCP2,SMPD3,SH3BGR,ITSN1,SH3GL3,PPM1E,DZIP1,ANKRD6,SLC6A8,OGDHL,SMARCD3,SNAP25,DOP1A,ZSWIM8,IZUMO4,SPP1,PEG10,ZBTB43,ACSBG1,SYT11,SYN1,SYT1,TAC1,CAMTA1,WDR7,ATP13A2,ZMAT3,TMOD1,BEX4,RBFOX2,TPM1,RUNDC3B,TST,SGK3,PLPPR2,CLIP2,TUBA1A,SLC17A7" Coexpression M1949 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.01E-11 2.32E-07 2.73E-09 2.71E-08 103 349 "KCNH8,FAM43B,XKR4,DSCAML1,GALNT13,SLC12A5,ALK,DPP10,SEMA7A,VAT1L,AMER3,CPNE5,CADPS,ATP2B2,ATP2B3,CADM3,ADGRB1,HCN2,CACNA1I,CDK5R2,CABP7,CDH8,DLGAP2,CLGN,NOG,CACNA2D2,CHRNA4,SULT4A1,MYRIP,C1QL2,ABCG1,RGS6,RASGEF1C,KCTD8,DSCAM,CNNM1,TMEM132E,ELAVL3,ACTL6B,FOXG1,FOXF2,TMEM151A,GABRA5,GABRB1,CPLX1,C1QL1,INSM2,GNAS,GNG4,GRIK3,PTPRT,IGSF21,NXPH3,HRH3,HMX1,IGFBPL1,TLX1,SHISA6,PLD5,SLC6A17,KCNA1,KCNH1,KCNK1,KCNK3,KCNQ2,NEFH,NEUROD2,VWA2,HCN1,SNTG1,PENK,PPP2R2C,PRPH,LAMA1,PTPRN2,IQSEC3,RASGRF1,CRTAC1,RET,PLPPR3,SCN4B,SLC30A10,STUM,MAST1,SORCS3,RAP1GAP2,CLSTN2,STAC2,TMEM150C,COBL,UNC5D,CNTN2,PHF24,RALYL,PRMT8,FAM155A,RBFOX3,KCNK12,SLC30A3,XKR7,TMEM163,DOCK8,JPH3" Coexpression M11011 Genes down-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.21E-11 2.55E-07 2.97E-09 2.95E-08 59 159 "BIN1,APLP1,ASPA,ATM,LINC00847,SYNJ2,MTMR2,MYRF,CAPN3,ARHGEF2,COL4A5,ARHGEF10,ST18,SPOCK3,SRPK3,OLIG2,EPHA5,EFS,ABCA8,CACNG3,PTK2B,CAP2,FOLH1,GPR37,LAMP2,MAG,MAPT,SCAMP5,MOBP,MOG,MX1,NKX2-2,NTRK2,P2RX7,PCSK2,CDK18,ENPP2,PIK3R1,PLP1,PMP22,MAPK8,KLK6,RASGRF1,RDX,RNASE1,SOX10,KIF1B,NFASC,SS18,CNTN2,TF,DICER1,TIAM1,LILRA4,TRIO,UGT8,CLDND1,SF1,LRP8" Coexpression 19861896-SuppTable1 Human Brain_Castells09_424gebes GeneSigDB 2.38E-11 2.75E-07 3.16E-09 3.14E-08 108 373 "SERPINA3,ACTN2,AGT,ALCAM,CNTNAP1,GAS7,BCAS1,ASTN1,ALDH7A1,ATP6V0A1,RIPK1,MAP7,CDH2,PLEKHB1,JAM2,LHX2,RAB33A,CNTN1,CLIP3,SIPA1L1,CTNND2,SPOCK2,DNAJC6,ELMO1,TMCC2,DNM1,DSCAM,EBF1,LPAR6,SORBS3,EIF5,CERCAM,ELAVL4,ENO2,APC2,ETV1,FABP7,TUBB3,TUBB4A,EFEMP1,FCGRT,MAD2L2,FOXM1,GPR153,TPPP3,FYN,CHL1,GAD1,NEK6,GFAP,FREM1,GHR,PPARGC1A,SPIN1,PSRC1,GPM6A,GPM6B,GPR17,GRIK3,GSN,MFSD2A,GUCY1A1,HLF,IGF1,IL6ST,JAK2,KCNQ2,LAMP2,STMN1,MAOB,LYPLAL1,MT3,SCG3,NCAM1,NCAM2,NOVA1,NRCAM,IGSF11,PDE4B,SMOX,PSAT1,EXOSC10,SCHIP1,RETREG2,PRKACB,PTPRN,PTPRZ1,RALGDS,RAVER2,BAALC,SATB1,SCN3A,RASA3,SH3GL3,KIF16B,CPEB3,FNDC3A,ST6GAL1,SLC1A2,SMARCD3,SUPT5H,PSD3,TNS2,TEK,TGFBR3,THBS4,PRDM2,TUBA1A" Coexpression 15273739-SuppTable2 Human Intestine_Jinawath04_1553genes GeneSigDB 2.47E-11 2.85E-07 3.24E-09 3.22E-08 264 1164 "ABHD6,PLEKHG5,ADCYAP1R1,ADRA1D,ADRA1B,AP1B1,CASKIN1,SRPX,BCAR3,CDC42BPA,EP400,ANXA7,APBB2,NT5C3B,AQP6,CDC14B,MIER1,MADD,CDK13,DDX3Y,EIF4G3,ZNF582,ATP6V0A1,ADAM15,SEC11C,BCHE,DCAF5,ZNF599,CFLAR,SYNJ1,C5,CACNG1,KALRN,CAMK2D,TRIM41,SLC25A14,CARS,HIP1R,RHBDL1,CCKBR,ENTPD2,NEURL1,MAGI1,COPB2,CHGA,CLU,TJP2,DNAJB5,QKI,HECTD1,COL9A1,MYRIP,MFSD4A,NECTIN3,CDC42BPB,CREB5,ANKRD44,NCOR1,CSF2RA,OSBPL3,SIPA1L1,CHD5,FAM131B,DOCK4,HDAC9,PHYHIP,DGKG,DCC,DCT,C2CD2L,RHOBTB1,NTM,USP3,DNM2,DYRK1A,SEZ6L2,EDNRA,FRY,SIDT2,KMT5B,TUBD1,OLIG2,EPB41,MFSD10,SEZ6,VPS26C,RRAGB,ECSIT,EZH1,CLVS1,FAM198B,EFEMP1,CEP78,FER,FOXO3,SPECC1,PDLIM5,CAMKK2,STAU2,SDCBP2,PHYHIPL,GABBR1,GABRA4,CAB39,FAM120B,ACSS1,ARFIP1,GFRA2,PCDH17,CSDC2,HTATSF1,MAP7D2,GNAL,GPER1,GRIN2D,GRM7,GRM8,GSN,GSTT2,MAEL,HBA1,HMGCL,CPT1C,DHX35,HTR2A,HTR5A,USP54,ZNF385B,ITPKB,KCNJ16,KCNK1,KCNQ2,KLC1,KPNA5,LIMS1,LSS,ASPRV1,SMAD1,MAP6,MBP,ADAM11,MEIS1,MEIS2,KITLG,AFDN,MOG,DBNL,MX1,MYH3,MYH7,NUCB1,NUCB2,OGDH,OPCML,P2RY1,PBX1,PCDH9,PCSK1,PDE3A,PDE4A,GDAP1L1,SERPINI1,PIK3R1,KCTD15,RC3H2,SEPT4,PPARA,MED1,PPP1R1A,LRRN3,PPP3CC,PPP5C,CEP41,MAPK3,MAPK9,SLC22A23,SYTL2,GON4L,NKAIN1,RASGRF1,ARID4A,RDX,RET,RNASE1,ZFHX4,SETD5,HSD11B1L,KCNIP3,RXRA,ZNF331,AMER2,SCN2B,SLC30A10,GALNT10,SGK1,SCG5,ITSN1,FAM102A,PPP1R9A,ST8SIA1,SLC1A2,SLC6A8,ARHGEF40,ATF7IP,SLC22A4,CPEB4,ARFGAP1,NAXD,TTC17,ZNF415,PALLD,MYO16,USP33,SOX2,TNIK,ARHGAP26,ZBTB43,NFASC,LMO3,SRPK2,POGZ,ERBIN,ST5,VPS13A,SEMA4A,CAMTA1,DNMBP,TAL1,TNS2,PCDHA6,RNF175,THRA,TK2,PRRT1,CSMD1,RBFOX2,TPD52,TPM1,TPM2,WBP2,PPIL6,TSC2,TST,TTC3,UGT8,CCDC14,MICAL1,VSNL1,CLIP2,KCNT2,TRIM9,ZBTB16,MAP3K12,PRDM2,LRP8,STOX2,RNF103,SEMA3B,MDH1B,SNX14,IFT88,DPF3,SPATA13,SENP7" Coexpression M2697 Genes down-regulated in NCI-60 panel of cell lines with mutated TP53 [Gene ID=7157]. MSigDB C6: Oncogenic Signatures (v6.0) 2.50E-11 2.89E-07 3.25E-09 3.23E-08 67 192 "GRAMD1B,MTUS1,KCNAB2,GAS7,APOC1,APOC2,RGS20,DDX3Y,ADAM23,BCHE,NRP2,ST3GAL5,CA12,CAPN3,SLC16A4,MYOM2,CHGA,GAL3ST1,IFFO1,CPS1,ARHGEF10,VCAN,GREB1,ZFYVE16,RASSF2,DCT,GSDME,ARNT2,KBTBD11,DOCK2,PLXNC1,NCALD,ST3GAL6,NSG1,CHL1,GFRA1,GLDC,GLS,IFI16,L1CAM,MATK,MITF,TAGLN3,LYRM9,MYO5A,NEFM,NRCAM,PDE1A,PDE4B,LAMA1,ELOVL2,PTPN13,SLC6A15,S100B,SGK1,ST8SIA1,SOX10,SPP1,SPART,EPB41L3,KANK1,AJAP1,TNS2,BEX4,VGF,VLDLR,NAV3" Coexpression 18855877-TableS2 Human Sarcoma_Filion09_404genes GeneSigDB 3.59E-11 4.15E-07 4.61E-09 4.58E-08 92 302 "NDRG2,ADARB2,C1QTNF3,ARHGDIG,ZBTB10,B3GALT2,ADGRB3,SYNJ1,MTMR3,RGN,CDH8,CDH10,DLGAP1,NDST3,CLCN3,FADS2,MAP4K4,ABI3BP,MYRIP,NECTIN3,CLOCK,HAPLN1,CSF1,VCAN,CTNND2,RIMS2,ZNF337,TBC1D5,SPOCK3,RCAN1,DTNA,EDIL3,SEMA3D,MBNL2,ELAVL2,PCOLCE2,RCAN2,ETV1,CORO2B,ST3GAL6,FGF12,FGF14,FHL1,GABRA1,GABRA4,GABRB1,GAD2,GFAP,GNAO1,GPR12,SCRG1,HPSE2,IGSF1,BRINP3,KCNJ16,KCNMA1,MBNL1,LRP1B,MMP16,PDE3B,PGAM2,PHKG1,PDZRN4,PRKACB,RELN,MARCH1,PID1,RET,KLHDC8A,SCN2A,SH3GL3,SYBU,SLC1A2,ZNF365,BTBD3,SLC14A1,SNCA,USP33,SOX5,ATP10B,COLGALT2,EPB41L3,EHBP1,RALYL,SLC19A3,LEFTY2,SLC44A1,TLR4,TRIM9,ADAMTS9,RTN4,NETO2" Coexpression 18362358-Table7 Human Leukemia_Calln08_1020genes GeneSigDB 3.99E-11 4.62E-07 5.08E-09 5.04E-08 161 633 "CDC7,USP31,KIDINS220,INTS2,MTUS1,OSBPL8,SEMA6A,CDC42BPA,PPFIA1,APBB2,USP37,CDC14B,SFMBT2,TMEFF1,ASPH,NUMB,EIF4G3,ATP2A2,ATP2B1,MTMR2,NIPA1,OSGIN2,ZNF555,CALM1,CAST,MAGI1,CFL2,CHN2,JAM2,RAB28,CLCN4,NMT2,QKI,HECTD1,TBPL1,ENTPD4,RNF14,ARHGEF10,SOCS5,PDE4DIP,DZIP3,ARHGAP32,TOMM20,DNAJC6,ZBTB24,MYEF2,MFAP3L,FBXL5,G3BP2,CDON,DMTF1,GNE,DYRK1A,PHF20L1,KMT5B,KCTD3,PLEKHA1,TMEM35A,PAN3,USPL1,EPS8,DLC1,FKTN,PRKAG2,CAMSAP1,SYNCRIP,RGPD5,JKAMP,NBEA,UFM1,NPTN,STAG2,HBS1L,GALC,ERAP1,TUBGCP4,GHR,MALT1,GLS,ZNF638,NR3C1,BVES,HPS5,FRMD5,HSF2,IDH3A,DOCK7,KIF2A,IPO5,NCOA7,MBNL1,KCTD6,KITLG,MTR,NEK1,SLC11A2,NUCB2,OPA1,ZNF827,PFKFB2,ANLN,CCSER2,RETREG1,POU3F2,PPM1B,PRKACB,PKN2,PTCH1,PTPN13,PTPRG,RAD17,SLC6A15,SLC25A36,PBRM1,RNASEL,RPRD1A,ATXN7,ANKRD6,WDR47,SEPHS1,SLC12A2,LIMCH1,CMTR2,USP33,SCN3B,SOX11,CLUAP1,EMC1,ZC3H13,ARHGAP26,KIF1B,ITPRID2,NXT2,ELOVL4,NECAB1,PLCB1,SYT1,ATP11A,EHBP1,TCF7L2,TCF12,PSD3,ARHGEF12,ZFPM2,AP4E1,TIAM1,TPD52,TRIO,AMACR,TRPS1,UBE3A,NSD2,CLDND1,PCDH20,TRIM9,SPIRE1,UPF3A,SLC38A1,RNF103,RNF146,SOCS4" Coexpression M2506 "Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.29E-11 6.12E-07 6.60E-09 6.56E-08 55 146 "ALCAM,ARHGDIA,ATP1A2,BCHE,NRP2,RUNX1T1,INA,CHGA,CHN2,NRXN1,CNR1,HAPLN1,ST18,ZEB2,EDNRA,EEF1A2,LPAR6,RASL12,DLC1,SORBS1,GAP43,MSTN,STMN2,GSN,CELF3,SCRG1,IFI16,KCNN2,L1CAM,MDFI,MEF2C,MITF,SCG3,TAGLN3,NEFM,NHLH1,NNAT,PCDH8,PDGFRA,PMP22,LRRN3,SCN3A,SLIT1,SLN,SNAP25,ZCCHC24,SOX10,EMC1,SPP1,NFASC,SST,STMN4,PCBP4,SLC17A6,ST7" Coexpression M7184 Genes up-regulated in glioblastoma cell lines displaying spherical growth (cluster-1) compared to those displaying semiadherent or adherent growth phenotype (cluster-2). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.31E-11 6.14E-07 6.60E-09 6.56E-08 17 21 "ADGRB1,ADGRB2,ADGRG1,CRMP1,OLIG1,OLIG2,CSPG5,DLL3,PCSK1N,GRIA2,HES5,MAP2,SHC3,PTPRZ1,HES6,ADGRL3,VANGL2" Coexpression M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.67E-11 7.71E-07 8.21E-09 8.15E-08 81 256 "BIN1,SHROOM2,MARCH3,CADM3,DGKI,REPS2,CDH2,CDH18,LOC730101,FOXN3,CHN1,ARHGAP22,MAGED1,NECTIN3,LRIG1,MICAL2,VCAN,SLITRK5,SDC3,DOCK4,TOX,ARMCX2,RHOBTB1,SV2A,RGS17,PCOLCE2,EML1,ENO2,RCAN2,EPS8,ABCA8,DLC1,FGFR1,PNMA2,GK,GLRB,FERMT2,PRUNE2,GRB10,RNFT2,HAS2,ITGA7,KCNMA1,MITF,NAP1L3,NPTX2,DDR2,PCDH9,ENPP2,PMP22,PRRX1,PTX3,PID1,FAT4,ENOX1,RGS4,ZFHX4,RPS6KA2,GALNT10,SCG5,DOCK10,CCDC92,ABLIM3,ARHGEF40,SLC22A4,CDK5RAP2,RIMS1,ZCCHC24,RGL1,SYT11,TBL1X,SATB2,ZEB1,SYNE1,TGFBR3,BEX4,TPM1,WIPF1,ATP6V0E2,ZBTB16,NAV2" Coexpression M2875 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 7.09E-11 8.20E-07 8.63E-09 8.58E-08 54 143 "NME5,ANK3,ASTN1,ATP1A2,NOL4,CDK5R1,CALB1,CDR1,CHGA,CHGB,KIAA1549L,ERC2,DOCK4,ARHGAP24,SNAP91,NTM,DYNC1I1,USH1C,RCAN2,ETV1,ST3GAL6,GABRA1,GABRA3,GLDC,TOX3,GPR19,HAS2,KCNH2,KIF5A,KIF5C,SCG3,NAP1L2,NRCAM,KCNK10,PCDH8,PDE2A,MAPK10,RELN,PTX3,SLC6A15,RNASE1,RTN1,SCN2A,ASIC4,SCG5,SNAP25,SPP1,BEX1,LMO3,SYT1,HEY1,WNT7A,MKRN3,NAV3" Coexpression 21205295-TableS2 Mouse Viral_Buonomo11_116genes GeneSigDB 7.65E-11 8.85E-07 9.22E-09 9.16E-08 44 105 "ADRB2,DOC2A,APBA2,APLP1,APP,ASCL1,BMP7,CDK5R1,CACNA1A,HAP1,CDH2,CHRM1,SLIT2,CRMP1,HDAC9,SEMA3D,ERBB2,FGF1,OLFM1,FGFR1,FGFR3,CSPG5,DLL3,NEU3,CIT,KNDC1,HES5,LAMA2,MAPT,MYCN,MYO6,NCAM1,NF1,NOVA1,PTN,SCN8A,HES6,SOX2,SOX11,HHIP,THBS4,HEY1,HEY2,VLDLR" Coexpression 18787218-tableS1 Human Liver_Chao09_1031genes GeneSigDB 8.15E-11 9.43E-07 9.72E-09 9.65E-08 170 684 "ELFN2,TMCC3,GRAMD1B,ADORA2A,ESYT2,OSBPL1A,BIN1,VAT1L,RGS20,ASPH,ZBTB10,DDX3Y,RNF182,NRP2,BMP7,DST,SYNJ2,SGCE,CAMK2D,INA,ARHGEF2,CDH2,NOG,UBE2L6,CHGB,CLU,TJP2,CNN3,MAGED1,AHCTF1,AKAP12,DOCK4,DGKG,SIRPA,CNIH3,MFAP3L,GSDME,NTM,ARNT2,NR1D2,DPYSL2,FIS1,E2F5,SNX29,TSPAN5,EDN1,PLXNC1,PCOLCE2,ETV1,CORO2B,DLC1,ST3GAL6,CHST15,FGF1,PRKAG2,FHL1,CAP2,FOXF2,TACC2,SORBS1,KHDRBS3,PNMA2,GABRA5,SYT17,GART,DNER,GNAS,GPR19,GRB10,GUCY1B1,RASSF8,FRMD3,IFI16,DIPK1A,L1CAM,TTYH2,LSS,SMAD9,MARK1,MATK,MBP,MKLN1,AFDN,MN1,MYO6,BEX5,NAP1L3,NBL1,NOVA1,NPTX2,NRCAM,PRTG,PDE2A,SLC10A4,SLC25A23,MAPKAP1,SPATA6,SH3KBP1,DRAM2,PPARA,PPP3CA,CNNM2,SYTL2,ZIK1,PTPRG,TUG1,PID1,OXR1,RASGRF2,VEPH1,SLC6A15,FIGN,STK32B,SALL1,ATXN1,TNFRSF19,PEAR1,SEC14L1,SGK1,SCG5,FERMT1,KIF16B,HKDC1,FHOD3,ABLIM3,DHX30,SLC14A1,ZKSCAN3,PALLD,DOK5,SPP1,PEG10,BEX1,SMOC1,EPB41L3,ZC4H2,SS18,DIP2A,KANK1,SULF2,AJAP1,ATP11A,PDLIM2,FBXW11,PCDHB6,PCDHAC2,SLC35G2,FAM200B,TGFBR3,TIAM1,TIE1,NACC2,HEY1,TJP1,CBX5,BEX4,PARD3,TRPM2,TTTY15,UBE2H,UGT8,VLDLR,ZNF711,LYPD6,PMEPA1,PRTFDC1,SCG2,CAB39L,UBE3B,NHSL1" Coexpression M18979 "Genes up-regulated in T1 cells (primary melanoma, sensitive to TRAIL [GeneID=8743]) compared to G1 cells (metastatic melanoma, resistant to TRAIL)." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.71E-11 1.01E-06 1.03E-08 1.02E-07 150 584 "ACADM,ADD3,KIDINS220,OSBPL1A,OSBPL8,CDC42BPA,PPFIA1,APC,SHTN1,ARHGAP5,ATM,BLM,BMP7,CAST,CCK,KRIT1,CCNH,ADGRG1,SRSF11,NIPBL,COL9A3,TCEAL2,DZIP3,APPL1,CTNND2,TCAF1,ZFYVE16,DCT,JAKMIP2,MYEF2,KIAA0319,CEP170,FBXO25,DDX46,SACS,DYNC1I1,CASP8AP2,DNM1L,ATL1,OPTN,PHF20L1,PLXNC1,NSRP1,RPS6KC1,TAOK3,FER,OLFM1,FGF13,POLK,SUCO,SMC2,FYB1,STAG2,ZNF44,RAPGEF6,IQGAP2,PPARGC1A,DBF4,ZNF638,HTATSF1,GOLGB1,GPM6B,GPR19,KIF3A,HAS2,ZHX1,HMGB1,IFI16,IGF1,ITGAV,KIT,IPO5,KTN1,LIG4,MATN2,MID1,MITF,MTR,MYO5A,MYO6,MYO9A,NAP1L1,FXYD6,NAP1L3,NRGN,NUCB2,OPA1,PCSK5,ENPP2,PENK,ANLN,SNX10,RETREG1,VPS13C,SPDL1,PTPN13,USP47,RAD17,RBBP6,RBBP8,RDX,REV3L,PBRM1,CLIP1,TRAPPC13,AP1AR,RMI1,SCP2,HSPA4L,DOCK10,DZIP1,ZNF430,BTBD7,ATF7IP,ARFGAP1,GKAP1,SNAP25,PALLD,SON,BDP1,MYCBP2,SPP1,RBM26,ZNF302,EPB41L3,SULF2,FAM208A,AGTPBP1,TCEA1,TCF4,TRIM2,DOCK9,SLC35G2,ITGB3BP,TPD52,UBE3A,USP1,VLDLR,WRN,NPDC1,XPO1,XRCC4,ZBTB38,ZNF195,SMARCAD1,UPF3A,C12orf4,ACTR3B,SSPN,FXR1" Coexpression M1714 Genes enriched in oligodendrocytes in the adult mouse brain identified through correlation-based searches seeded with the oligodendrocyte cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-10 1.33E-06 1.34E-08 1.33E-07 35 74 "ERMN,HCN2,MYRF,CD81,PLEKHB1,QKI,AATK,ARHGEF10,OLIG1,OLIG2,TPPP3,GATM,GJB1,GPR37,GSN,OPALIN,TTYH2,MAG,MBP,MOBP,MOG,NRBP2,OMG,ANLN,SEPT4,FA2H,QDPR,SGK1,SOX10,SYT11,CNTN2,WSCD1,SLC44A1,DAAM2,UGT8" Coexpression M10276 "Genes down-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-10 1.66E-06 1.66E-08 1.65E-07 47 118 "TTYH1,TKTL1,MTUS1,BEGAIN,LGR5,FGF17,PROM1,BMP7,WASF1,LGI1,PLEKHB1,SLIT2,LHX2,QKI,COL4A5,COL9A3,CREB5,CNTNAP2,MFAP3L,CHRDL1,DMD,DTNA,EMX2,F3,FABP7,EFEMP1,FOXG1,C1orf61,PDLIM5,FUT9,GATM,FAM107A,WIF1,NACA,NELL2,GRAMD1C,TMEM255A,FEZF2,DGLUCY,HSPA4L,PALLD,SOX3,SPART,SYNE2,ZMAT3,ZIC1,NAV3" Coexpression 19139136-TableS3 Human Prostate_John-Aryankalayil09_2212genes GeneSigDB 1.83E-10 2.11E-06 2.09E-08 2.08E-07 330 1547 "RALGAPA1,SERPINA3,ADCY2,ADCY6,BRAP,CDC7,GRAMD1B,ADORA1,RNF150,ADRA1D,HECW2,OSBPL6,SPARCL1,BEGAIN,ANK2,PHF12,SHROOM2,IGDCC4,TMEFF1,ARRB1,CDK13,ASPH,BRINP2,NCOA1,ASTN1,INSYN2B,ATP2A2,ATP2B1,ATP6V0A1,KIF1A,BARD1,SEC11C,BLM,ST3GAL5,SYNJ2,IL33,CAMK2D,PRC1,KYAT1,SCARB1,SYNGR3,NEURL1,REPS2,TIGD7,CLGN,RCBTB2,SRSF11,CHI3L2,CHN2,SLIT2,CPNE6,RAB33A,PPT2,FAM189A2,FADS2,CCDC151,COL4A5,MAGED1,GAL3ST1,ACBD5,PREPL,RNF14,SIPA1L1,PDE4DIP,CNTNAP2,CMTM5,CTH,CTNND2,HDAC9,ARHGAP32,PHF19,IP6K1,AIF1L,SIRPA,DNAL1,ARMCX2,CNIH3,MFAP3L,RUSC2,MED24,MTX3,RPS6KL1,CDON,SLC12A6,PDCD6IP,RCAN1,ARRDC4,ECM2,MAMLD1,ABCC9,E2F5,KLHL5,FRY,FSD1L,RBM12,YAF2,EGFR,KMT5B,ELAVL2,TNK2,CALCRL,PAN3,HSD17B14,RCAN2,DMTN,LRRC23,CDKL3,ETV1,SIRPB1,ZNF461,DLC1,FDFT1,GORAB,FER,FGF1,FGF12,SCARA3,SEC23B,FOXM1,EFCAB2,JKAMP,SMC2,TPK1,NPTN,PRELID3A,KHDRBS3,GPR153,DLL3,MSANTD4,TPPP3,FYN,ZNF44,GABRB3,DENND2A,GAD1,TMEM8B,ACSS1,SRCAP,CYP46A1,GFER,GGT5,GK,RAB30,KCNMB4,GNG4,FERMT2,PSRC1,ADGRA3,GPR19,NUDT21,ATE1,PRDM5,CIT,FICD,HAS2,PADI2,ARHGAP19,NCKAP1L,SYNPO,HMGCR,HNF4G,HSP90AA1,SMAP1,ICA1,ZIC5,KNDC1,IL12A,TUBB2B,KCNMA1,STMN1,MAP2,MAP6,MBD1,IL17D,MDM4,MEF2C,MIA2,N6AMT1,CTNNA3,MYH3,MYO5A,MYO9A,NASP,NCF2,NFIA,PCBP3,NRGN,DDR2,NUCB2,OPHN1,CLDN11,PC,PDE4B,GNG2,TMOD2,ABCB1,SERPINI1,PIK3C2A,TMIE,ANLN,PIK3R1,RETREG1,XRN1,GPSM2,PLP1,PMP22,TRHDE,PACSIN1,TATDN3,PPP2R2C,PRKAB2,PRKAR1B,SLC26A11,HYDIN,PRODH,KLK6,LRRC49,LAMA1,WDR25,PXK,STK32A,PTPRN2,FAM120C,PTX3,MARCH1,RAB3IL1,ZNF793,SH3TC2,FAT4,GTDC1,RGS7,RGS10,TTLL7,PGBD4,NEK11,PRR5L,LGR4,RTN1,CCDC112,RMI1,FOXRED2,SARS,SBF1,ASIC4,IL17RB,MRAS,KIF27,NLGN4Y,SCG5,SH3BGR,PPP1R9A,ARX,NTNG1,SYBU,SLC1A3,SMTN,FAM214B,LRRC55,SLC8A3,ZNF334,EPC1,TTC17,SCN3B,FNBP1,ZHX3,ZSWIM8,CLUAP1,KDM4C,UNC5B,ST5,MPRIP,ZSCAN29,ELOVL4,SEPT3,NSFL1C,FGD4,SYNE2,SYT1,SLC37A2,TACC1,ROBO3,MCF2L,ADGRL3,TMEM136,TCF7,ZEB1,AKNA,TNS2,SIK3,ITGB3BP,NACC2,HEY1,CBX5,DDHD1,TMPO,BEX4,ANKRD24,RBFOX2,NPL,PPIL6,TSC1,SGK3,FAM155A,UBE2H,CLEC2L,PLEKHH2,NSD2,WNT7A,WRN,ZNF24,ZNF32,ZFP41,LYPD6,REEP1,ZNF189,SPIRE1,FTSJ1,DHX33,ZXDA,LRP8,LMAN2L,SEMA3B,PCDH15,CAB39L,PARP11,RGS7BP,ZNF248,MSRB3,SSPN,FRMD6" Coexpression M2719 Genes down-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH). MSigDB C6: Oncogenic Signatures (v6.0) 1.92E-10 2.22E-06 2.15E-08 2.14E-07 67 200 "RALGAPA1,UNC79,ARHGAP5,DYNLL1,ATP2B1,MTMR9,DST,BSN,THSD7A,CALM1,CAMK2D,SEPT7,LRRFIP1,FOXN3,MAP4K4,IQCK,AKAP12,ERC2,SPOCK2,DGCR5,NTM,AK5,KBTBD11,TSPAN5,ATL1,FRY,ENO2,SRRM1,TUBB3,ATP8A1,CHST15,GLS,PCLO,LINC01089,UBE2QL1,BACH2,HSP90AA1,TUBB2B,MAP2,NAP1L1,NAP1L2,NCF2,PAK3,PFKFB4,PKIA,PTPRD,NUDT11,SCG5,ITSN1,ANKRD6,SLC15A2,PALLD,EPB41L3,PHLDB1,STXBP1,SYT11,SYPL1,ARHGEF12,TJP1,RASD2,TRPC1,UBTF,BCL2L13,NDRG4,PRDM8,GAL3ST3,SLC17A7" Coexpression M9178 Genes down-regulated in CD4 [GeneID=920] T conv over-expressing: GATA1 and SATB1 [GeneID=6304;2623] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.92E-10 2.22E-06 2.15E-08 2.14E-07 67 200 "ACADM,ACTN1,ADCY6,RNF157,ARHGAP20,MAP4K3,PKP4,DGKD,BCAS1,SFMBT2,RASL11B,NRP2,C5,CA8,DDR1,FMNL3,ZMYM4,ABCG2,MAP4K4,MFSD4A,CRY2,DZIP3,GREB1,GPSM1,ARHGAP24,KIAA0586,DAPK1,CTIF,ANKRD46,EIF4G2,ENO2,EPB41L2,ARMCX1,ADAMTS6,ZDHHC15,CELF5,MSL1,TUBB2B,KCNH2,KIT,KTN1,HECTD2,SRSF12,KCTD6,SMOX,PACSIN1,MAPK7,GTDC1,SATB1,ATXN2,RASA3,ST8SIA1,DZIP1,POGZ,LARP4,GSE1,ATP11A,AGTPBP1,KLHL4,TCF7L2,AHCYL2,TP53BP1,TTC3,TUBB2A,VAV2,PMEPA1,NT5M" Coexpression M1539 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) after 5 days of cocaine [PubChem=5760] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.34E-10 2.71E-06 2.60E-08 2.58E-07 36 79 "ACTN1,ADORA1,ADORA2A,AP2A1,MTMR9,BTRC,CAMK2A,CCK,SPOCK2,DLG4,ELN,TUBB4A,CORO2B,ACTL6B,BAIAP2,NPTN,TBR1,GAD1,GRIA1,GRIA4,PTPN5,KCND2,NELL2,NRGN,PALM,PDE4B,PDE1B,PENK,FBXW7,STX1B,SEC14L1,SH3GL3,SOX10,STXBP1,SYP,HPS4" Coexpression M10952 "Genes up-regulated in the atria of healthy hearts, compared to venticles." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-10 2.94E-06 2.80E-08 2.78E-07 78 249 "ACTN1,ADORA1,DGKZ,CADPS,CDK13,PDE8B,ATM,SGCE,CACNA1B,DDR1,CD81,CDO1,CACNA2D2,CHGB,RAB33A,MAGED1,FEZ1,MICAL2,VCAN,GPRASP1,RABGAP1L,CHRDL1,EDNRA,TNK2,ENO2,EPB41L1,EPS8,ERBB2,ERBB4,EFEMP1,ERGIC3,CHL1,GABRB3,OS9,GNAO1,PRUNE2,GRIN2C,SYNPO,INPP1,KCNJ3,KCNK1,KCNK3,PTOV1,MYBPC1,MYH6,NAP1L1,NPPA,SLC11A2,NTRK2,DDR2,NUCB1,NUMA1,PDE2A,PDE4B,CDK14,PLP1,LRRN3,RELN,PTH1R,KCTD17,ITSN1,ZNF365,SLN,NMNAT2,UNC5B,EPB41L3,GSE1,ABCC8,PLCB1,KAZN,RALYL,TGFBR3,LILRA4,TRPC1,TUBB2A,FLRT2,VSNL1,RTN4" Coexpression 18614019-TableS4c Mouse StemCell_Fazzio08_2031genes GeneSigDB 2.72E-10 3.14E-06 2.95E-08 2.93E-07 273 1239 "ABHD6,EMILIN3,NCKAP5,TKTL1,ACTN2,ADAR,ADCY2,TMCC3,AXIN2,HECW2,PCDH19,ALCAM,ALK,BIN1,SEMA7A,MAGEE2,ALS2,CACHD1,VAT1L,BCAS1,USP37,APP,CPNE5,MARCH3,NCOA1,ATP2B2,KSR1,DST,WASF1,IL33,MMD2,FOXK1,CALB1,KALRN,PTBP2,SLC25A14,CAPN3,CH25H,NFS1,METTL6,DLGAP2,DLGAP1,CHGA,LHX2,NRXN1,CLU,VAX2,SULT4A1,CNGA3,TBPL1,IGDCC3,SLC35F1,FAM171B,C2CD2,CRHBP,SNCAIP,TENM4,LRRC3B,PDE4DIP,PHACTR3,CNTNAP2,PLXNA4,RASGEF1C,FAM131B,CYBB,DOCK4,TBC1D5,KCTD8,BRINP1,DCC,SPATA2,TIAM2,MFAP3L,C2CD2L,TMEM130,RHOBTB1,FAM107B,DMD,DYNC1I1,CPEB2,ECM2,DNAJB6,ABCC5,PHC2,FEM1B,EEF1D,PLXNC1,AASS,ELAVL3,PCOLCE2,RCAN2,LRRC17,RCSD1,SCML2,FGF1,FGF13,BAIAP2,FOXG1,AGAP2,FLNC,ATP13A4,FLT1,ZCCHC17,PDLIM5,TPPP3,ZMAT1,MEGF11,GABRA1,CAB39,DISC1,IGSF5,PCDH17,RND1,CBX1,OS9,GPD1,PCLO,GRIA1,ATE1,GRM5,GSN,BVES,MFSD2A,FICD,RASSF8,NCKAP1L,GABARAPL2,HMX1,BTBD17,MYLK2,NKD1,SCIN,DIPK1A,JAK1,KCNA1,OLFM3,KCNN2,STXBP5,ASPRV1,EFHB,MEIS2,MMP17,SESN3,MSRA,MYCN,MYH3,MYH6,MYH7,NBL1,NEFM,NEFH,NINJ2,NODAL,NPY,NPTX2,NRGN,DDR2,TREM2,PCDH8,PCSK5,PCSK2,PDE2A,PENK,DUSP26,SSH1,PLCL1,PURG,MAGEL2,SEPT4,SH3KBP1,IRX1,PPP2R2B,PPP2R5E,PPP3CA,RASGEF1B,CEP41,SKOR1,HYDIN,RELN,SYTL2,SNRK,PTPN13,PTPRD,PTPRE,PTPRG,PTPRO,PTPRZ1,RIPOR1,MARCH1,PLEKHB2,ZCWPW1,ZMAT4,TRIM68,RGS10,TTLL7,KLHL11,ROBO1,LRRK2,LGR4,RXRA,RXRG,RYR3,CSRNP3,SMPD3,GALNT10,SFPQ,ITSN1,DOCK10,SLC1A6,PREX2,SLC6A8,TMEM132D,EFHD1,EPC1,INTS9,LIMCH1,PDZRN3,ZHX3,UNC5B,ZC3H13,CDK19,SPART,CLSTN2,STOX1,THSD1,APOM,ACSBG1,SYT11,ZC3H4,ABCC8,RHBDL3,PLCB1,SYN2,TAC1,POPDC3,SEMA4A,ROBO3,ALG1,ADGRL3,ACSL6,DOCK9,ARHGEF12,ZNF106,THBS4,DDHD1,RIMBP2,PARD3,TNS1,IL34,SYNPO2,DCBLD1,TMEFF2,UBC,AMOT,FLRT2,FAM181B,SF1,ZIC3,CFAP52,LYPD6,FSTL5,DPYSL5,ZFAND5,DHX33,PRDM2,LMAN2L,TMEM178A,EPM2A,FZD3,TMEM63C,JMJD1C,NETO2,DPF3" Coexpression M12892 Genes up-regulated in the luminal B subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.73E-10 3.16E-06 2.95E-08 2.93E-07 60 172 "SERPINA3,ABAT,ASCL1,BMPR1B,BAIAP3,LDLRAD4,CA12,CACNA1D,CAMK2B,RHBDL1,REPS2,CACNA2D2,CHGA,CHN2,RAB26,GREB1,MAGI2,ARNT2,EEF1A2,CELSR3,KCTD3,ERBB4,ZMYND10,EVL,TPPP3,SYT17,GPR162,GFRA1,GLRB,TOX3,PCLO,GRIA2,PTPRT,IL6ST,INSM1,KCNJ3,KIF5C,MAPT,MYT1,NELL2,NOVA1,SERPINI1,RETREG1,NKAIN1,QDPR,RET,STK32B,SYBU,SLC8A2,IFT122,KDM4B,CLSTN2,SSTR2,ABCC8,SYT1,TNNT1,DNAJC12,TRIM9,DNALI1,SEMA3B" Coexpression M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.25E-10 3.76E-06 3.49E-08 3.46E-07 127 480 "C1QTNF1,SRPX,ANK2,CACHD1,ATP1A2,KSR1,DST,JAZF1,SGCE,IL33,CCK,CFL2,SRSF11,CHN1,CLU,ANKRD35,COL9A1,TCEAL2,CNRIP1,AKAP12,FEZ1,GPRASP1,SCRN1,ARMCX4,HEPH,CHRDL1,DMD,DTNA,OPTN,SH3GLB1,TMEM35A,ENO2,RCAN2,EFS,SPEG,RASL12,MRVI1,EFEMP1,FGFR1,FHL1,FLNC,C2orf88,SORBS1,FYN,DKK3,SALL3,GATM,TNRC6A,GNAL,FERMT2,GPM6B,BTN2A1,MFSD2A,WIF1,UBE2QL1,HLF,SCRG1,INPP1,KCNJ3,KCNMA1,KIT,LSAMP,GPR155,MEIS1,KITLG,LAYN,FXYD6,NBL1,NCAM1,NEFH,NELL2,NPR2,DDR2,ZNF827,PCDH9,PDE4A,PENK,PIK3R1,PLCL1,PMP22,PRRX1,PPP3CC,MASP1,BEND5,PRRT2,PRIMA1,RAVER2,PNMA8A,ROBO1,KIRREL1,TMEM100,MEG3,SEMA6D,GALNT10,MRAS,FHOD3,PREX2,ARHGEF40,SLC14A1,INAVA,PALLD,UNC5B,MIR100HG,SMOC1,EPB41L3,ST5,TACC1,GPR161,TGFBR3,ARL10,TNS1,TPM1,TPM2,SYNPO2,TRO,TUB,PLEKHH2,CCDC136,TMEM237,PARP6,STOX2,TUBA1A,NAV2,VANGL2,MSRB3,SSPN,FRMD6" Coexpression M2440 "Genes up-regulated during neuronal differentiation of SH-SY5Y cells (neuroblastoma) in response to stimulation by tretinoin (all-trans retinoic acid, ATRA) [PubChem=444795] and BDNF [GeneID=627]." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.56E-10 4.12E-06 3.75E-08 3.73E-07 15 18 "ASIC1,ANK2,SYNGR3,CNR1,SNCAIP,GABBR1,KCNB1,KCND1,KCNK2,SCN2A,SCG5,SYT11,SYT5,CA10,KCNAB1" Coexpression M17173 "Genes up-regulated in the nucleus accumbens (a major reward center in brain) 8 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.57E-10 4.13E-06 3.75E-08 3.73E-07 26 47 "ADAR,ADCYAP1R1,ADORA2A,HCN2,CAMK2A,SYT6,USP2,ARHGEF2,CDH2,CHRM1,CLCN4,DNAJB5,CRY2,RASSF2,ARNT2,TSPAN5,GAD2,GNAO1,GRIA2,GRIN1,KCNB1,KCNH1,KIF5A,PRKCB,ST6GALNAC6,KIF1B" Coexpression 19286929-SuppTable2q Mouse Lung_Rangasamy09_1540genes GeneSigDB 3.87E-10 4.47E-06 4.03E-08 4.00E-07 223 974 "RBM10,ABHD6,CSMD3,CCDC85A,GALNT13,MTUS1,KLHL13,CC2D2A,ABCD2,OGT,DDO,CACHD1,TMEFF1,PDE8B,ASPA,ASPH,DYNLL1,ATM,EIF4G3,MTMR9,B3GALT2,IL33,CALB1,PTBP2,TRIM41,ARHGEF25,LRRFIP1,DIS3L,RCBTB2,CHN2,NGEF,ARHGEF6,ACBD5,MFSD4A,CPS1,PNKD,SNCAIP,PDE4DIP,GREB1,TCAF1,PABPC5,ARMCX4,ARMCX2,PLEKHM1,MFAP3L,CEP170,DTNA,ECM2,ATL1,RBM12,PHF20L1,KMT5B,ELAVL2,STX2,SRRM1,NCALD,VPS26C,RCSD1,EYA1,GMPR2,EZH1,ARMCX1,FAM198B,AMZ2,WAC,TMEM132C,ST3GAL6,CEP78,POLK,HPCAL4,EVL,JKAMP,PDLIM5,DACH2,FUT9,FYB1,PHYHIPL,ZMAT1,GABRA1,GABRA2,GABRG1,GAD1,HBS1L,FAM120B,GATM,GFRA1,PCDH17,GHR,GLRB,GLS,TOX3,MSL3,CBX1,RFFL,GRM5,MUM1,ATG4C,NCKAP1L,MIER3,HNMT,AGFG1,IRF8,RIPPLY2,METTL21A,CLVS2,KLHL23,STXBP5,LIG4,LMO2,MBNL1,CHIC1,TM6SF1,MGAT3,CD200,SAMD5,RSPO2,NAP1L2,NAP1L3,NEUROD1,NNAT,NPPA,NPTX1,SMIM11A,OCRL,PCSK5,SSH1,HMGCLL1,PLXNB1,PURG,ING3,POLG,PTCH1,ZIK1,TTC13,RAD52,FAT4,ARID4A,RBBP6,GTDC1,RFX3,DCUN1D2,TMLHE,ROBO1,ROBO2,TMEM206,RPL38,PRR5L,ADAL,RPS6KA2,ATAT1,SEMA6D,SFPQ,SUPT20H,TRA2B,ZFP30,MAGI3,CHD9,ST6GAL1,DZIP1,PEX26,SMTN,CCDC88A,MTERF2,EPC1,CXXC4,INTS9,RCOR3,RIMS1,MBD5,FAM126B,PDZD2,KDM4C,DBNDD2,TROVE2,ST5,SULF2,FAM168A,SYT11,FGD4,SYNE2,VPS13A,SYN2,ASTN2,ANKRD12,DDHD2,TAF9,SMG6,NSD1,ZMAT3,CBX5,TMOD1,ANKRD24,R3HDM1,TPD52L2,SYNPO2,METTL3,STXBP4,TRPM2,DCBLD1,TSC1,SSBP2,TTC3,PRR18,MEAF6,VSNL1,WRN,PORCN,XPO1,AMZ1,FSTL5,ANKS1B,FTSJ1,ZFAND5,INTS3,PRDM8,NAV2,SNX27,MPPE1,GOPC,FAM13C,ST8SIA2,SPATA13,SENP7" Coexpression M10761 Genes up-regulated in the HMEC cells (primary mammary epithelium) upon expression of the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.87E-10 5.64E-06 5.03E-08 5.00E-07 100 353 "DPF1,ABHD6,PLEKHG5,APAF1,EPB41L5,CACHD1,TNRC6C,ARRB1,MARCH3,KSR1,SYNJ2,CABP7,CAPN3,NPIPA1,FOXN3,SLIT2,CLU,QKI,ARHGEF6,WHRN,COL9A3,ZNF385A,PDE4DIP,PPP1R16B,TOX,DLG4,RCAN1,SEZ6L2,RASGRP1,FRY,EFNA3,ELAVL3,RASGRP2,APC2,DLC1,FGF13,FOXF2,SEMA4D,FOLR2,DPYSL4,KHDRBS3,OGA,GPT2,GP1BB,GPR37,LINGO1,CELF3,UBE2QL1,HSPA1L,SHISAL1,KCNH2,KCNK3,KIT,LMO2,SMAD9,HS6ST3,MX1,LINC00672,RCOR2,NPTX1,OXTR,PCSK5,PLCD1,EPB41L4B,TNPO2,PPP2R2C,PPP3CC,PSD,PTX3,RET,HUNK,SOX8,SEMA6D,ELMOD1,IL17RB,ARX,SHC4,NBPF1,LIMS2,EFHD1,GKAP1,TMCC1,ZCCHC24,UNC5B,ARHGAP26,EPB41L3,SYNE2,ATP11A,TACC1,FRYL,TEX15,HEY1,HEY2,ZIC2,ELFN1,REEP1,STOX2,ADAMTS10,ST8SIA2,SPATA13" Coexpression M1914 Genes up-regulated in neural stem cells (NSC) at 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.12E-10 5.92E-06 5.24E-08 5.20E-07 87 293 "ABAT,ACTN1,NDRG3,AGT,SORCS2,APAF1,APBA2,APLP1,IGDCC4,KIF1A,CFLAR,RUNX1T1,CLDN10,USP2,CRLF1,CLU,DNAJB5,RCHY1,CP,CREM,AATK,SNCAIP,CSF1,CST3,IP6K1,CTIF,SIRPA,FBXO25,SRGAP3,DTNA,SEZ6,FCGRT,FGF1,OLFM1,BAIAP2,POLK,FOXO3,SORBS1,PHYHIPL,USP19,PCSK1N,GRIA2,GSN,GSTM5,KCNC1,VWA5A,ZFYVE27,MEF2C,NELL2,NNAT,P2RY1,PALM,PDE1C,PDE2A,PFKP,PKD1,TMEM38A,PLCD1,SMOX,PCDH18,PRRX1,SEPT4,SLC22A23,GDPD2,PTPRE,PTPRO,PYGM,RIPOR1,RALGDS,RFX5,S100B,DGLUCY,ST6GAL1,SLC4A3,EFHD1,CPEB4,SPP1,SULF2,MLC1,SYNE1,ZMAT3,THRA,NACC2,SEZ6L,RFTN2,TMEFF2,NDRG4" Coexpression M19529 Genes down-regulated in anaplastic thyroid carcinoma (ATC) compared to normal thyroid tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.42E-10 6.27E-06 5.50E-08 5.47E-07 137 533 "ABAT,AXIN2,PLEKHH1,KIDINS220,MTUS1,GPRASP2,NT5C3B,CACHD1,ARHGAP5,ZSCAN18,SLC4A4,DPY19L3,AZGP1,ST3GAL5,CALM1,FMNL3,SLC16A4,DGKI,ZBED1,MAGI1,SLIT2,FBXO7,IQCK,SLC25A27,ABI3BP,PNKD,AKAP12,LRIG1,FEZ1,GPRASP1,ARHGAP24,DCAF8,GIT2,PITPNC1,ARMCX2,MAGI2,SMG7,CDON,ECM2,EDNRB,ANKRD46,FRY,SIDT2,FAM13A,PHF20L1,EGR3,WAC,FECH,FGF13,TMEM164,FHL1,SCARA3,TACC2,ZBED3,PDLIM5,ST6GALNAC3,ZMAT1,WASF3,SESN1,GHR,ZNF638,GNAS,LNX1,WDFY3-AS2,ADGRA3,GPM6A,GPM6B,GSN,TMEM25,AP4S1,ATOH8,USP54,ZNF678,LIFR,VWA5A,SMAD1,SMAD9,MATN2,IL17D,MEF2C,DDX25,NDUFA5,NF1,CLDN11,PBX1,PDE4A,PFKFB2,ZFYVE21,SLC25A23,PCDH18,EPB41L4B,TATDN3,PPP3CB,PKIA,SNRK,PTPRB,PTPRD,PTPRG,SNX22,ADAL,RXRA,DGLUCY,CSRNP3,SGK1,CCDC92,ANKRD6,ARHGEF40,SHANK2,ATF7IP,ZCCHC24,FNBP1,DOK5,TEX2,NPAS3,SYNE2,TMEM150C,DDHD2,TCF4,NSD1,AHCYL2,SLC44A1,HEY1,BEX4,KCTD2,TNS1,SYNPO2,SSBP2,HIRA,TOM1L2,ZNF711,ATP6V0E2,TMEM178A,KCNAB1,PLSCR4,PDSS2,RNF170,KLHDC1" Coexpression 18537972-TableS2 Human Leukemia_San Jose-Eneriz08_1151genes GeneSigDB 5.68E-10 6.56E-06 5.71E-08 5.67E-07 220 962 "SYN3,ACHE,ADCY8,BRAP,OSBPL1A,C1QTNF3,DOC2A,CDC42BPA,APBB2,BCAS1,SEMA4G,MADD,ARHGDIG,ASCL1,PDE8B,ZSCAN18,BCHE,FGF17,CFLAR,ARHGEF7,FUBP1,CA4,NGB,SLC25A14,CCK,MTMR7,INA,CD86,NEURL1,ARHGEF2,CDC27,NDST3,ZFYVE9,NRXN1,QKI,NIPBL,HOMER3,COL4A5,TBPL1,NCOR1,SNCAIP,OSBPL3,ATRNL1,DZIP3,CTH,GREB1,ARHGEF4,CTNND1,ECE2,KIAA0408,HDAC4,TM9SF4,TBC1D5,DAPK3,BRINP1,DCC,DCT,CNIH3,TIAM2,SGSM2,TMCC2,KBTBD11,EXOG,DNM1,DMPK,ATN1,ABCC9,EDNRB,KLHL5,CELSR3,PHF20L1,SUGP2,AASS,EIF4G2,IRAK4,TENM1,TNK2,ZNF391,ANKMY1,FAM198B,CACNG2,ATP8A1,ZMYND10,FER,FGF12,TMEM164,CAMSAP1,FOXO3,POMT1,GABRA4,GAP43,DISC1,INPP5K,GART,LYVE1,RND1,OS9,GOLGB1,PRRC2B,GRIA2,NR3C1,GRM1,GRM5,GSTM5,AP4S1,CELF3,HMX1,TLX1,HSD17B1,IRF8,DIPK1A,INPP5B,KCNA6,KCNJ10,KCNQ3,KIF5C,KLC1,PACRG,PTOV1,TAGLN3,MYT1,FXYD7,NAP1L2,NDUFA5,NFIX,NOVA1,NTRK2,NTRK3,SETD4,OCRL,PC,PCDHGC3,PDE4A,PDYN,GPR173,PFKFB4,ABCB1,PIK3R1,EPN1,MTRF1L,MAPKAP1,PPP3CC,MASP1,BCAS3,APTX,TMEM104,PTCH1,PTHLH,SPDL1,PTN,PTPRD,FAM120C,CCDC40,RAP1GDS1,RBBP6,GAL3ST4,RGS12,S100B,DZIP1,SLC12A2,ATF7IP,SMARCA4,IGSF9B,SNAP25,KIF13A,KDM4B,TNIK,FNBP1,ZSWIM8,UNC5B,ZNF423,DBNDD2,SPTAN1,SPTB,FCHO1,MAPK8IP3,SEPT8,JMJD6,ABCC8,ARHGEF9,PLCB1,TACR1,TAF6,IQCE,WSCD1,TCF4,SATB2,ZEB1,PUM2,CRTC1,PCDHA5,SLC35G2,SIK3,PMS2CL,NACC2,ACTR6,TLL2,SMUG1,TRIO,PDSS1,TRPC3,ZMYND8,TMPRSS5,TSC2,UBE3A,USP1,VIPR2,ZNF23,TRIM9,ZNF45,SPHK2,ANKS1B,EVI5,LMAN2L,RNF103,ADAMTS9,SEMA3B,MVB12B,PAK5,SENP7" Coexpression M687 Genes up-regulated in neurons after NPAS4 [GeneID=266743] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.80E-10 7.86E-06 6.78E-08 6.73E-07 57 163 "TTYH1,ABCF1,C3orf14,ADD2,ARHGAP20,LRFN1,RNF182,ARHGEF7,PLCXD3,NRSN1,SPOCK2,KIAA0319,MTX3,FAM107B,RCAN1,C8orf37,TMEM74,VPS26C,DNAJC27,CAMSAP1,ATP2C1,PNMA2,GABRB1,TMEM8B,PCDH17,KIF3A,ACOT7,STXBP5,MSI1,FXYD6,ALDH1L2,NTRK3,PCSK2,PFKFB4,CDK14,PTPA,PRKAB2,PKIA,RASGRF2,RBBP6,BSDC1,TSPY26P,SCN3A,MRAS,SGK1,ST6GAL1,FAM81A,SLC8A1,TRIM67,RBM34,C3orf70,DDHD2,AP4E1,SMUG1,MKRN3,LYPD6,MARCH8" Coexpression 19286929-SuppTable1 Mouse Lung_Rangasamy09_2003genes GeneSigDB 7.33E-10 8.47E-06 7.24E-08 7.19E-07 340 1621 "ABCF1,ACTN1,ACTN2,SLC25A25,FMNL2,CCDC85A,TMCC3,ADCYAP1R1,ADD1,ADD3,BRAP,ADRB2,AP2A2,MTUS1,OSBPL6,SORCS2,TAOK1,ALCAM,BCAR3,LTBP4,PITPNM2,AMPD3,CDC42BPA,ANK3,SEMA7A,PKP4,ANXA7,API5,APP,SHROOM2,PRX,ARNTL,CDK13,ASPH,ATP1A1,ATP1A2,ATP2B1,ATP2B2,ATP6V0A1,MYOM1,BACH1,NRP2,GPR146,DST,DDR1,PTBP2,CAMK2D,CANX,CBR1,USP2,SCARB1,CD38,MYOM2,ARHGEF2,SEPT7,CDC42,MAGI1,CCPG1,ADGRG1,SOCS6,RAB3C,CLU,TPP1,CLTB,FAM189A2,ABCG2,HECTD1,NIPBL,COL4A5,SLC4A7,ABI3BP,MYRIP,CP,CLOCK,CDC42BPB,C2CD2,CRY2,GDA,ABCG1,LRIG1,CSNK1E,CSNK1G3,ATRNL1,CTNND1,PUM1,USP6NL,GPRASP1,LONRF1,MATR3,DAPK1,TOMM20,SPOCK2,DBT,SPATA2,ELMO1,RUSC2,DDX46,G3BP2,RABGAP1L,FAM107B,USP3,NR1D2,DNM2,CPEB2,SLC12A6,PDCD6IP,RCAN1,ARRDC4,DTNA,DYRK1A,EDN1,EDNRB,PHC2,HIPK3,FEM1B,KLHL5,TMTC1,FRY,SH3GLB1,FAM13A,EGFR,ABI2,SORBS3,EIF5,ELN,EIF1,RTN3,HSPA12B,F3,WAC,ACSL4,ATP8A1,ST3GAL6,CHST15,SEC24B,FGF1,FGF13,FGFR3,BAIAP2,FHL1,IP6K2,PCYOX1,SYNCRIP,FLT1,TACC2,SORBS1,UFM1,PDLIM5,TRIM16,OGA,SDCBP2,GAA,GALNT15,AHCYL1,B4GALNT1,MTHFD2,IGSF5,GCNT2,SESN1,PCDH17,MALT1,LYVE1,DBF4,GLS,GLUL,OS9,GNAO1,GPT2,PRRC2B,LILRB4,STON1,CECR2,TUBA1C,RAPGEF4,STMN2,RAPGEF1,GRIA1,MFSD2A,FAM107A,GUCY1A1,GUCY1B1,WIF1,HPS5,VSIG4,HMGCL,NKD1,IL6ST,ITPKB,JAK1,KCNK1,KIT,SMAD1,GPR155,MAPT,MBD1,KCTD6,MKLN1,AFF1,PTOV1,MXI1,MYH6,MYH7,MYO5A,SLCO1C1,NFE2L2,NPTX1,P2RX7,PCMT1,PDE2A,PDE4B,PDGFRA,PFKFB3,FAM98B,PGAM2,PIK3R1,SNX10,ZFYVE21,RETREG1,PLEC,SMOX,PLTP,STRN3,RC3H2,LRP12,PSAT1,PPM1B,PPP2R5C,PPP2R5E,RASGEF1B,PRKAR1B,PRKCZ,GDPD1,SLC22A23,PSMA6,SNRK,QRICH1,ANKHD1,PTPRB,PTX3,USP47,CCDC40,RBBP6,ZDHHC14,RDX,ZYG11B,RGS12,RIC8B,RPRD1A,TMLHE,ELP2,RPS20,WLS,TRA2B,HSPA4L,SGK1,MAGI3,CLSTN1,EPN2,LIMS2,SEPHS1,SIRT2,SLC12A2,SLC15A2,SLC20A2,LGI3,EPC1,ZFP1,CDK5RAP2,SMARCE1,SNCA,MBD5,PDZRN3,DOP1A,SON,PDZD2,WDTC1,TNIK,KDM3A,ZHX3,SP2,KIF1B,TSPYL2,SPART,LARP4,ERBIN,NCDN,GANAB,MLC1,JMJD6,SYNE2,ATP11A,MCF2L,TAF9,DNMBP,ADGRL3,TBCEL,ATMIN,TCF12,CLASP1,DOCK9,ARHGAP9,AHCYL2,DICER1,CHST8,TGFBR3,TIE1,DDHD1,ZFP91,TMOD1,DAAM2,BEX4,PARD3,TNS1,RBFOX2,TPM3,WBP2,PRMT8,TSC2,LRTM2,TTPA,ZKSCAN5,UBC,RPL7L1,EIF4ENIF1,UBE2H,SLC35A4,TBC1D15,TSPAN11,RICTOR,SF1,ZBTB16,ZFAND5,WNK1,MAP3K12,PRDM2,LRP8,ADAMTS9,SEMA3B,FIP1L1,RNF146" Coexpression 15785748-Table3 Human Uterine_Santin05_178genes GeneSigDB 7.44E-10 8.61E-06 7.30E-08 7.25E-07 54 151 "SPARCL1,PDE8B,DST,IL33,CACNB2,RUNX1T1,LDB2,GPRASP1,RIPOR2,HEPH,CHRDL1,DYNC1I1,DPP6,ECM2,EDNRA,EDNRB,LRRC17,ABCA8,PRUNE2,GPM6A,STON1,GUCY1A1,HLF,IGF1,KCNB1,KCND3,KCNMA1,MATN2,MEF2C,NAP1L3,NTRK2,DDR2,PDGFRA,ENPP2,ABCB1,PLCL1,FXYD1,PLP1,PMP22,PRRX1,MAPK10,PTN,SMTN,PDZRN3,ZCCHC24,ZEB1,TNS2,TEK,LEFTY2,TGFBR3,THBS4,RUNDC3B,FLRT2,ZBTB16" Coexpression 18614019-TableS4b Mouse StemCell_Fazzio08_466genes GeneSigDB 7.70E-10 8.91E-06 7.48E-08 7.43E-07 90 309 "MTA3,MTUS1,WDR35,BCAR3,PDZD4,PPFIA4,CNIH2,APC,SFMBT2,IGDCC4,ZBTB10,BCL7A,PTBP2,ARHGEF25,CDC42,LRRFIP1,MAGI1,CLIP3,FEZ1,CSNK1E,DCAF8,DBN1,PITPNC1,DNAJC6,MFAP3L,DMPK,DTNA,SLC43A2,EPS8,EFS,EYA1,POLK,TACC2,ZBED3,TRAF3IP2,TOX3,DCLK2,GNAS,GPT2,PSRC1,B4GALNT4,GRB10,HAS2,KLF12,CELF5,MSL1,MDM4,MID1,AFDN,NRBP2,NCAM1,NNAT,ODF2,P2RX7,KCTD15,RAP1GDS1,FIGN,SLC25A36,LGI2,UEVLD,MEG3,RTKN,SALL1,HES6,CHD9,ST8SIA1,SLC1A3,TRIM67,SMARCC2,IFT122,RIMS1,KIF13A,SOX11,CAND2,JMJD6,WSCD1,PCDHGA11,ZMAT3,ANKRD24,RBFOX2,TPM3,TPM4,TRIO,TRO,TRPS1,RPRM,WIPF1,MAP3K12,SLC38A1,RNF170" Coexpression 20436685-ST4-1 Human Breast_Pothuri10_811genes GeneSigDB 7.79E-10 9.01E-06 7.51E-08 7.46E-07 181 760 "RBM10,CDC7,AK2,BIN1,AMT,OGT,CDC42BPA,ANK3,PKP4,APBB2,DGKD,APOC1,LGR5,CDC14B,MARCH3,ADAM23,BID,MTMR3,CACNA1I,CA12,MAP7,PRC1,LRBA,DCLK1,ZMYM4,ADGRG1,CHRNB2,ZBED5,ARHGAP22,PLAA,CLCN3,CLCN4,FADS2,LY86,SLC4A8,CP,C2CD2,CRYBB1,AATK,LRIG1,SOCS5,SLITRK5,KIAA0040,CTNND1,PUM1,GAPVD1,TCAF1,FRMPD4,ZFYVE16,MAML1,DBI,DNAJC6,MYEF2,MFAP3L,MAGI2,LYPD1,SRGAP3,ABI1,GNE,E2F5,RASGRP1,FRY,FAM13A,PLXNC1,VPS13B,KCNMB2,ERBB4,NCALD,RTN3,TLR7,DLC1,ST3GAL6,FER,SEC23B,SYNCRIP,ATP2C1,CELF1,FUT9,GAB1,GAD1,ADAM28,GK,CRCP,GLS,GNAL,GPR37,GRM8,FAM107A,ARHGAP19,HSP90AA1,IRF8,KCNMA1,IPO5,ARHGAP12,SMAD1,MARK1,MATK,MBD1,MBNL1,MEF2C,MEIS1,MGAT3,ADAM22,MSRA,NASP,OXTR,PAK3,PC,PFKFB3,PIK3R1,PLCL1,RETREG2,PRKACB,PKIA,MAPK9,BCAS3,SIDT1,PTAFR,SPDL1,PPP2R3C,RAD17,RBBP6,BSDC1,CRTAC1,SLC25A36,BAALC,MCMBP,MAP6D1,RPS20,RMI1,SCN2B,CASC3,ASRGL1,SUPT20H,ZFP30,AMBRA1,FNDC3A,ST8SIA1,ANKRD6,WDR47,SLC12A2,SMARCA4,OGDHL,SOX2,SOX3,TSNAXIP1,DOK5,UHRF1BP1L,UNC5B,RBM26,CLASP2,SEPT8,GSE1,ZC3H4,ARHGEF9,ASTN2,CAMTA1,EXOC7,DNMBP,CAMSAP2,KLHL4,EHBP1,PHF24,DNAH7,SIRT1,TNFRSF1B,ZMYND8,UBE3A,BCL2L13,VIPR2,WIPF1,XRCC4,ATP6V0E2,NDRG4,SPHK2,NAV2,TRIM16L,PARP11,PDSS2,SSPN,ST8SIA2" Coexpression M2324 Genes up-regulated in uterus upon knockout of BMP2 [GeneID=650]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.29E-10 9.59E-06 7.93E-08 7.87E-07 178 745 "NDRG2,KLHL32,ADCY6,TMCC3,AXIN2,PNMA8B,RNF150,ZNF608,KIAA1324,SORCS2,ALCAM,LTBP4,AMPD3,ANK3,SMIM29,PDXK,ATP1A2,ATP2B2,BCHE,GPR146,PROM1,BMP7,RAB29,CA12,DDR1,CALB1,CAST,CLDN10,SCARB1,REPS2,JAM2,CLU,FAM189A2,TJP2,ZNF521,CP,CRY2,GDA,CLIP3,SNCAIP,LRIG1,KIAA0040,GREB1,RIPOR2,DCAF8,DAPK1,SCRN1,SPOCK2,IP6K1,RHOBTB1,SV2B,RABGAP1L,ARNT2,DMPK,NR1D2,EDNRA,VPS13B,LRRC17,EPS8,NCALD,EFS,RCSD1,MRVI1,HSPA12B,F3,F5,SH3YL1,TMEM132C,ACSL4,PTK2B,EFEMP1,ATP8A1,FCGRT,SPSB4,IP6K2,FOXO3,AFF2,HVCN1,FUT9,GAA,GALNT15,HIGD1B,CPLX2,SESN1,GGT5,GHR,PSRC1,GPM6B,PARD3B,GSTT2,FAM107A,GUCY1A1,FAAP20,JAK2,SLC35G1,KCND2,KCNK1,LAMA2,LMO2,VWA5A,SMAD1,MATN2,MEIS2,SESN3,CCDC80,MYCN,FXYD6,NBL1,NFIA,NNAT,NPR2,NTRK2,NUMA1,OXTR,P2RX7,ENPP2,GNG2,ABCB1,PIK3R1,FXYD1,SLC25A23,PLTP,SEPT4,PRKAR1B,GDPD1,SNRK,PTH1R,PTPRB,PTPRD,REV3L,RGS3,RNASEL,WLS,RTKN,SATB1,CSRNP3,SCN7A,SH3BGR,PPP1R9A,PPM1E,KIF16B,CLSTN1,SLC6A9,RADIL,SLC15A2,SCMH1,INAVA,RIMS1,FNBP1,SPP1,BEX1,ADHFE1,PHLDB1,FGD4,SEMA4A,PDLIM2,TMEM136,TEK,THRA,TIE1,FAM124A,TNNT1,RASD2,SYNPO2,TRPS1,FNDC5,RUSC1,RFTN2,CCDC136,VLDLR,PORCN,NPDC1,ZBTB16,RGMA,KCNAB1,ITM2C,PLSCR4,MSRB3" Coexpression 19808871-TableS3 Human StemCell_Hassan09_1544genes GeneSigDB 8.52E-10 9.85E-06 8.03E-08 7.98E-07 239 1068 "TTYH1,ACADM,ACHE,ADCY8,ADD2,ADD3,KIAA1324,SEMA6A,AMPD2,AMPD3,PARG,APC,APP,CDC14B,CDK10,TMEFF1,RGS20,ASCL1,CHRD,ATM,ATP1A2,NOL4,ADAM23,BLM,BMP7,NAE1,CACNA1G,CDK5R2,CA4,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CAMK2G,CH25H,SPAG9,MAP7,PRC1,CBLN1,CBS,CCKBR,INA,SYNGR3,DGKI,AP4M1,REPS2,CDC25B,CDC27,LARGE1,CRLF1,SLIT2,LHX2,VAX2,CNTFR,IQCK,COL4A5,COL9A2,TBPL1,NRG2,CRMP1,LRIG1,FEZ1,PDE4DIP,CNTNAP2,CTNND2,RIMS2,DGKG,DBI,DCC,DCTN1,ZEB2,SV2B,DLG3,DNM2,DPYSL2,DTNA,DNAJB6,EEF1A2,CNNM1,EFNA3,EGR3,EN2,OLIG2,EPHA5,EPHB1,ERBB2,ERBB4,ETV1,PIPOX,ZIC4,OLFM1,FGF13,FGFR1,HPCAL4,FOXG1,FOXM1,DCTN2,TBR1,OGA,STAG2,GABRA2,GABRA4,GABRA5,GABRB3,GAD1,GAD2,MTHFD2,GART,GBX2,PCDH17,GHR,GLDC,MSL3,POLL,ADGRA3,GPM6B,ATF7,GPR12,GPR19,LPAR4,STMN2,GRIA2,GRIK1,GRIK3,GRM7,CIT,PTPRT,PSIP1,GUCY1A1,HAS2,HBA1,IFI16,IL11RA,ITPKA,KCNA1,KCND3,KCNH1,KCNK2,KCNMA1,KCNN2,KCNQ3,KIF5C,STMN1,LIG4,MAN2A2,MAPT,MAT2A,MDFI,SCAMP5,NAP1L1,NASP,NCAM1,NELL1,NEK1,NEUROD1,NEUROD2,NFIX,NPTX1,NTRK2,NUMA1,GPR88,PAX6,PCDH8,PDCD2,PDGFRA,ENPP2,PENK,TMOD2,CDK14,PLEC,PMP22,POU3F4,PPM1B,PPP3CA,PPP5C,MAPK4,PTHLH,PTPRZ1,QDPR,RAD17,RASGRF1,RBBP8,CRTAC1,REV3L,RGS10,ROBO1,RYR3,SALL1,SLC1A2,SLC6A1,PKNOX2,SLC6A8,SIRT2,SLIT1,NAXD,SMARCA4,SOX2,SOX10,SOX11,LHPP,CLASP2,TROVE2,SSTR1,SSTR2,SUPT5H,ABCC8,ASTN2,TAL1,TCF12,CLASP1,SIRT1,CHST8,HEY1,TK2,CBX5,ICAM5,TMPO,TNNT1,TPM2,TRH,TSC2,FLRT2,VSNL1,NSD2,WNT7A,SLC13A3,KCNK12,ZIC1,ZIC3,TRIM9,ZNF195,TFIP11,SLC30A3,CA10,SLC30A4,NT5M,LRP8,KCNAB1,FXR1" Coexpression M2018 Genes with low-CpG-density promoters (LCP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.54E-10 9.88E-06 8.03E-08 7.98E-07 29 58 "AGT,AMPD3,DDR1,CP,DAPK3,SLC25A18,ECM2,PIPOX,DUSP27,FABP7,FGF1,CAB39,GPD1,PLCD4,BTBD17,VWA5A,GPR173,MASP1,ZSCAN2,C1orf54,GAL3ST4,KCNIP3,MLC1,FGD4,AKNA,TNS2,TIMP4,PLPPR2,CAMK1G" Coexpression M9933 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 6h. MSigDB C7: Immunologic Signatures (v6.0) 1.16E-09 1.34E-05 1.07E-07 1.06E-06 65 199 "KCNH8,ACHE,FAM43B,DSCAML1,SRPX,KIF6,ANK2,STK33,CADM3,CACNA1D,HIP1R,ARHGAP33,NOG,MYL6B,CNR1,FAM149A,COL11A2,SLC35F1,OLIG1,EDNRA,TMTC1,LINC00599,CEND1,ATP13A4,PSD2,ADGRA1,HHIPL1,ABLIM2,DKK3,GABRB3,SYT17,GGT7,GNAO1,GRIK2,GRIK3,HTR5A,INSM1,C2CD4C,OLFM3,KCNJ16,INSYN2,SMAD9,NEFM,NEFH,TMOD2,RAB39A,TMEM255A,DBX2,CARF,MAP6D1,SCN4B,FAM19A1,ASIC4,KIF21A,CLSTN1,ZNF334,ARC,ACSL6,PCDHB7,RIMBP2,TTPA,TUB,HIRA,CLEC2L,PLPP4" Coexpression M7766 Genes up-regulated in macrophages 48h after M. bovis BCG infection: wildtype versus MYD88 [GeneID=4615] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.16E-09 1.34E-05 1.07E-07 1.06E-06 65 199 "HHATL,ANK1,C6orf89,USP2,MYOM2,ZMYM4,LGI1,ABCG2,AKAP12,AATK,BOC,AK5,CHRDL1,DYRK1A,EEF1A2,EXTL2,EZH1,ST3GAL6,CHST15,FLNC,COQ5,ZCCHC17,GPD2,RAPGEF4,BVES,PADI2,ARHGAP19,IDH3A,IDH3B,SCIN,ITGA7,KLHL23,LAMA2,MAP4,CHIC1,PPM1L,MSRA,NDP,NFIA,NOS1,NPR2,CCSER2,FXYD1,FITM2,RASGRF2,BSDC1,ZFHX4,TMEM100,MAPK12,SEMA6D,SMARCD3,PALLD,SPTB,COBL,ACSL6,FRYL,TF,AKTIP,ZFP91,TPM2,KCNE5,ATP6V0E2,TCEAL7,PDSS2,UBE3B" Coexpression M7978 Genes up-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468]. MSigDB C7: Immunologic Signatures (v6.0) 1.16E-09 1.34E-05 1.07E-07 1.06E-06 65 199 "NCKAP5,PLEKHG5,ADRB2,MTUS1,TBC1D14,TMEM263,ARHGAP5,CAPRIN2,CHID1,DST,C1QC,FOXK1,DDR1,MAP7,CLTC,ABCG2,CNRIP1,CRYBB1,FEZ2,RUBCN,DMD,LPAR6,PLEKHA1,EML1,EPB41L2,DUSP27,ZNF585B,FCGRT,ANKFY1,FOLR2,RAPGEF6,SESN1,GGTA1P,HPGDS,SPIN1,GPR34,VSIG4,USP51,ICA1,IGF1,HECTD2,ARHGAP12,GPR155,SCAMP5,NBL1,NFIA,SLC22A23,SIDT1,RASGRF1,ZDHHC14,GAL3ST4,LGI2,WLS,RYR1,SEC14L1,ST6GAL1,SLC1A3,BTBD7,USP33,LRRC4,IQCE,ATMIN,ARHGEF12,UBE2H,ITM2C" Coexpression 16014634-Table1 Mouse Brain_Hagemann05_93genes GeneSigDB 1.27E-09 1.46E-05 1.15E-07 1.15E-06 36 83 "ATP2A2,ATP2B2,CACNA1G,INA,CP,CSF1R,DLX1,ENO2,GABRA2,GAD1,GAD2,CPLX1,GFAP,GRIA1,GRIA2,GRIN1,GSN,ITGAM,MAG,MAPT,MEIS1,NEFM,NFE2L2,PAX6,PDGFRA,PLP1,PMP22,PTX3,STX1B,SLC6A1,SLC8A1,SNAP25,SPP1,SYP,SYT1,VAV1" Coexpression 19192944-TableS4 Human Ovarian_Crijns09_2394Genes_17PathwayPredictor GeneSigDB 1.29E-09 1.49E-05 1.16E-07 1.16E-06 332 1584 "ACTN1,ACTN2,ADCY2,ADCY5,ADCY6,ADCY8,AXIN2,CDC7,ADORA2A,UNC5A,ADRA1D,ADRA1B,ADRB2,NME5,SEMA6A,ALCAM,AMH,AMPD2,AMPD3,SEMA7A,MAP4K3,CNTNAP1,APC,LRRC4C,CDC14B,SEMA4G,CASK,ARHGAP5,ARRB1,ARRB2,PDE8B,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V0A1,MPDZ,FGF17,BID,BMP7,BMPR1B,ARHGEF7,CACNA1I,CACNA1G,WASF1,BTRC,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNG1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CLDN10,CCKBR,CCNH,INA,CD86,ARHGEF1,CD38,ENTPD2,ENTPD6,CDC25B,CDC27,CDC42,CDH2,MAGI1,CACNA2D2,CFL2,SOCS6,CHRM1,CHRM4,JAM2,TAOK2,SLIT2,NRXN3,NRXN2,NGEF,TJP2,MAP4K4,ARHGEF6,CNTFR,CNTN1,COX4I1,NECTIN3,ENTPD4,GDA,CSF1R,CSF3R,CSNK1E,SOCS5,CNTNAP2,SDC3,ARHGEF4,CX3CR1,CYBB,DCC,TIAM2,MAGI2,PARD6A,SRGAP3,AK5,DPYSL2,DRD1,DUSP9,E2F5,EDNRA,EDNRB,RASGRP1,SEMA3D,CACNG7,EFNA2,EFNA3,EFNB3,EGFR,ABI2,PLXNC1,EPB41,EPB41L1,EPB41L2,RASGRP2,EPHA5,ERBB2,ERBB4,APC2,ECSIT,CACNG3,CACNG2,PTK2B,FGF1,POLR1B,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,BAIAP2,MAD2L2,ATP5PD,SEMA6C,SEMA4D,FLNC,SORBS1,ATP6V1H,ABLIM2,FYN,NCKAP1,IQGAP2,GART,GCK,GHR,PPARGC1A,GJB1,DBF4,GNAL,GNAS,RAPGEF4,RAPGEF1,PLCD4,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GSN,PTPN5,GUCY1A2,GUCY1A1,GUCY1B1,WIF1,NCKAP1L,NEGR1,HTR2A,HTR5A,MYLK2,IGF1,NKD1,TJAP1,IL6R,IL6ST,IL11RA,IL12A,ITGA7,ITGAM,ITGAV,ITPKA,ITPKB,JAK1,JAK2,KIT,KLRC3,L1CAM,LAMA2,STMN1,LIFR,MAG,MAPT,MATK,SHC3,MEF2C,KITLG,AFDN,GIT1,MYL3,NCAM1,NCAM2,NCF2,NDUFA5,NF1,NME4,NOS1,NPR2,NRCAM,NTRK2,CLDN11,OXTR,P2RX7,PAK3,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4D,PDE1B,PDGFRA,ENPP2,PDPK1,PFKP,PHKG1,SSH1,SEMA5B,PIK3CD,PIK3R1,PKM,PLCB2,PLCD1,PLXNB1,PLXNB3,POLR2F,PPM1B,PPP2R2B,PPP2R2C,PTPA,PPP3CA,PPP3CB,PPP3CC,PPP5C,PRKAB2,PRKACB,PRKAR1B,PRKCG,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,MAPK10,PRPH,RELN,NDUFS7,LAMA1,PTK2,PYGM,RASGRF1,RASGRF2,RDX,RGS3,MYH14,ROBO1,RPS6KA2,RYR1,RYR3,MAPK12,SEMA6D,TNFRSF19,IL17RB,SELL,MRAS,SH3BP2,NTNG1,MAGI3,NLGN1,ABLIM3,SLC8A2,SLC8A3,CXXC4,SPP1,UNC5B,SPTAN1,EPB41L3,MAPK8IP3,TACR1,SEMA4A,ROBO3,UNC5D,CNTN2,FBXW11,TBL1X,TCF7,TCF7L2,ARHGEF12,THBS4,TIAM1,TJP1,DAAM2,TNFRSF1B,PARD3,TNR,PIK3R5,TRPC1,TSC1,TSC2,VAV1,VAV2,WNT7A,PORCN,SPHK2,DPYSL5,MAP3K12,NT5M,SEMA3B,FZD3,PAK5,VANGL2,SOCS4" Coexpression M2196 Genes significantly de-regulated (p < 0.05) by MIR21 [GeneID=406991] in A172 cells (glioma). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-09 1.55E-05 1.20E-07 1.20E-06 85 289 "SNX30,ESYT2,LCORL,APAF1,APC,GPAM,ALS2,MPDZ,LONRF2,SRSF11,FOXN3,HECTD1,NIPBL,ACBD5,CLOCK,HAPLN1,OSBPL3,GAPVD1,SCRN1,MYEF2,FBXL5,KLHL3,DDX46,DMD,GNE,RASGRP1,PHF20L1,PAN3,NBEA,SESN1,SPIN1,FERMT2,GPD2,CNTRL,LIFR,MEIS1,SAMD5,MYO9A,NEK1,DDR2,OLR1,PBX1,PIK3C2A,PIK3R1,PPARA,MINDY2,PRKAB2,CEP97,USP47,ARID4A,ZYG11B,REV3L,FIGN,PBRM1,ZNF532,ASRGL1,CPEB3,DOCK10,FBXO11,ST6GAL1,BTBD3,BTBD7,TET1,ZNF667,LIMCH1,PALLD,SOX2,FNBP1,MYCBP2,SRPK2,SYNE2,VPS13A,ANKRD28,TACC1,DDHD2,TRIM2,ARHGEF12,TLR4,TPM1,CCDC14,ZBTB38,WNK1,WNK3,CERS6,RSPRY1" Coexpression M8234 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype vs RORC [GeneID=6097] knockout treated with digoxin [PubChem=2724385]. MSigDB C7: Immunologic Signatures (v6.0) 1.82E-09 2.11E-05 1.62E-07 1.61E-06 58 171 "ACTN2,ADD3,LRRC7,PDZD4,USP37,CDC14B,SEMA4G,GPR146,CFLAR,CDK5R1,CAMK2D,FMNL3,PHF14,SRGAP3,CNNM1,ABI2,CORO2B,SLC37A3,CHL1,RAPGEF6,IQGAP2,GFRA1,MALT1,RAPGEF4,GSN,TOX2,ATCAY,IRF8,ITGAM,KTN1,STMN1,GPR155,PPM1L,CD200,RSPO2,P2RX7,PIK3CD,PKM,JAKMIP1,SH3KBP1,TMEM231,RGS10,CLIP1,IL17RB,SELL,FAM102A,PPM1E,SHC4,ST6GAL1,ST8SIA1,SLA,UHRF1BP1L,ARHGAP26,RPGRIP1L,TRIO,MAP3K12,CERS6,JMJD1C" Coexpression 17555561-Table1 Human Breast_Mackay07_1264GenesDownRegulated GeneSigDB 1.94E-09 2.24E-05 1.70E-07 1.69E-06 223 991 "SLC25A25,ADORA1,USP31,INTS2,SEMA6A,CEP126,KIF6,MAP4K3,PKP4,APLP1,LGR5,ARHGDIA,MARK4,ADAM15,AZGP1,ADGRB2,BCHE,RGS9,BCL7A,DST,MTMR3,MTMR2,BAIAP3,THSD7A,CALM1,PTBP2,CAMK2D,PRC1,ZNF501,LRBA,CDC42,CDH10,DLGAP1,ADGRG1,PPT2,NMT2,CLTC,FADS2,SULT4A1,HECTD1,NIPBL,SUMF2,COL9A1,IFFO1,MFSD4A,CREM,ENTPD4,NCOR1,CS,CSF1,RGS6,MICAL2,CSNK1E,RIMS4,PDE4DIP,CNTNAP2,PUM1,FAM131B,DCAF8,TBC1D5,YTHDC1,JAKMIP2,ZC3H11A,DDX46,PARD6A,WDR20,HS3ST2,TRAPPC9,DYNC1I1,FAM57B,DTNB,TOM1,DYRK1A,ABCC5,AASDH,SEZ6L2,TSPAN5,PHC2,FRY,PHF20L1,APH1A,EIF4G1,BSCL2,VPS13B,EPB41,MFSD10,PIPOX,CD320,OLFM1,FGFR1,IP6K2,PCYOX1,FOXO3,UFM1,STAU2,RAPGEF6,IQGAP2,SEPT9,STARD10,DNER,SRCAP,GFRA1,GFRA2,RNPS1,POLL,GNAS,PSRC1,GOLGB1,ATF7,PLCD4,CIT,COQ10A,TMEM25,KLF12,IBA57,SLC6A17,NME9,KCNC1,KCNJ10,KTN1,SFXN5,MAPT,GIT1,COL28A1,STK32C,BCO1,PTOV1,MYO5A,SLCO1C1,NFIX,NFYA,NOS1,PCBP3,NRDC,OGDH,ZNF827,CNTN3,DPY19L2P2,PDPK1,DUSP26,PLXNB1,MBOAT7,PACSIN1,FA2H,MAPK3,CNNM2,SNRK,PTHLH,ELOVL2,EML5,NKAIN1,QDPR,RAP1GAP,RBBP8,RGS12,ROBO2,ROM1,MCMBP,RTKN,SCN2A,HES6,IL17RB,SEC14L1,ZNF821,ASRGL1,PUF60,SH3BP2,BCAN,CLSTN1,PEX26,YPEL4,SLC11A1,SCMH1,BTBD7,CPEB4,ZNF667,IFT122,LIMCH1,SNCA,SNRPN,KDM4B,ZCCHC24,DBNDD2,SPTAN1,RBM26,NFASC,TAB2,GANAB,SYT1,COBL,ANKRD12,TAF6,TCF7L2,ARHGEF12,CRTC1,PCDHA6,FRYL,AHCYL2,DICER1,ZFPM2,TJP1,R3HDM1,PARD3,CABIN1,DOK6,ZMYND8,TMPRSS5,HSPBP1,TTC3,SGK3,ZNF138,CELF4,DPYSL5,ZNF195,SH3GLB2,NT5M,DNALI1,PARP6,PCBP4,PDSS2,ZNF37BP,TMEM63C,ST8SIA2" Coexpression M6100 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.94E-09 2.25E-05 1.70E-07 1.69E-06 78 259 "TTYH1,ELFN2,GALNT16,PLEKHH1,ZNF608,EPB41L5,APLP1,CADM3,ADGRB2,MYRF,LDLRAD4,VXN,CDC42,LRRFIP1,NMT2,MAGED1,TCEAL2,CRMP1,HAPLN1,SDC3,TCAF1,JAKMIP2,TIAM2,LYPD1,EBF1,EDIL3,EDN1,EFNB3,RASA4,AASS,MTSS1L,FDFT1,FGFR1,BAIAP2,EFCAB2,PNMA2,DKK3,JPH4,SYT17,CSDC2,GLI2,TOX3,GSN,NXPH2,HMGCR,TUBB2B,ITGA7,KCNA1,L1CAM,LSS,MATN3,MEIS1,FXYD6,NAP1L3,NFIA,GPR137C,ZNF827,PBX1,PDE1C,CYTL1,CCSER2,PTPRN,SCN2B,COPZ1,ARHGEF40,SOX2,INKA2,TCF4,TRIM2,PCDHB10,OBSL1,TK2,CBX5,TNS1,TRO,VGF,SYNC,TUBA1A" Coexpression M9331 "Genes down-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.12E-09 2.46E-05 1.85E-07 1.84E-06 79 264 "ACTN2,ELFN2,ADORA2A,OSBPL6,PCDH10,ALS2,DDO,ASCL1,CACNA1B,CABP7,SYT6,RUNX1T1,KYAT1,MYOM2,CCDC151,SLC25A27,NECTIN3,HAPLN1,SUSD5,NCAN,NRSN1,FAM131B,SLC29A4,C3orf18,SPEG,EYA1,ADGRA1,TBR1,GABRA2,ARPP21,PSRC1,PRUNE2,CECR2,GRIA1,GRIK1,SCRG1,SCRT2,INSM1,KCNC1,KCND2,KCNH2,KCNJ3,KCNK1,MYBPC1,NEXMIF,NCAM2,NFIA,SNTG1,PCDH9,NXPH1,PPP2R2C,SKOR1,PTAFR,PYGM,SLC25A41,MRAP2,STX1B,DGLUCY,TMEM200C,SOX6,SH3BGR,ITSN1,RUFY2,SLN,NPAS3,APOM,WWC1,CUX2,THBS4,DAAM2,TNR,TP53BP1,CLHC1,HEPACAM,PLEKHH2,ZIC1,CADM2,SEMA3B,NAV2" Coexpression M2775 "Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi." MSigDB C6: Oncogenic Signatures (v6.0) 2.36E-09 2.74E-05 2.04E-07 2.03E-06 52 147 "ASPHD1,GAS7,API5,SLC4A4,PROM1,CH25H,MAP7,SLC16A4,CDH10,CRLF1,UBE2L6,COL9A3,TCEAL2,SEC31B,CREM,CLIP3,EDN3,REEP2,FCGRT,PDLIM5,CHL1,PPARGC1A,STON1,ITGA7,KCNJ16,MAOB,NEFH,GPR88,PCDH8,PCSK1,PDE3A,PDE4B,PENK,CYTL1,SERPINI1,C1orf54,PNMA8A,KANSL3,EFHD1,OGDHL,SOX2,DOK5,NMNAT2,ZNF423,LMO3,CUX2,TRIM2,NR2E1,TMOD1,EVI5,SLC17A6,SSPN" Coexpression M6920 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.84E-09 3.28E-05 2.43E-07 2.42E-06 40 100 "NDRG3,ADCY6,OSBPL1A,SEMA7A,AQP4,CADPS,MPDZ,CCK,INA,MFSD4A,TSPAN5,ELAVL2,FABP7,TUBB3,OLFM1,FGF12,TBR1,GABRA1,SYT17,CPLX1,STMN2,ACOT7,SMAP1,STMN1,MEF2C,MMP16,MOBP,NEFM,NEUROD2,NPY,CDK14,SERPINI1,PTPRD,FBXW7,SH3GL2,SST,SSTR2,STX1A,SYP,NACC2" Coexpression 17760805-SuppTableS2a Human Leukemia_Boag07_100genes_pre-BALLvCD34_UP GeneSigDB 3.09E-09 3.57E-05 2.63E-07 2.61E-06 34 78 "SEMA6A,PPFIA1,DGKD,LGR5,PDE8B,CALM1,LARGE1,RCBTB2,MYRIP,ARHGEF10,ARHGEF4,DLG3,MAMLD1,AMZ2,FGFR1,TRAF3IP2,GPM6B,LILRA2,PCLO,PPP3CC,PTK2,MORC4,ITSN1,ZSWIM8,ZNF423,RGL1,VAMP1,CAMSAP2,SIN3B,PCDHGC5,PARD3,CLIP2,KCNK12,TFIP11" Coexpression M2571 Genes down-regulated during prostate cancer progression in the JOCK1 model due to inducible activation of FGFR1 [GeneID=2260] gene in prostate. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.34E-09 3.86E-05 2.82E-07 2.80E-06 88 308 "OGT,CACHD1,LGR5,PDE8B,SLC4A4,MYOM1,PROM1,CACNA2D1,CBS,P2RX6,LGI1,GPR37L1,CHN2,RAB26,ABI3BP,FAM171B,GREB1,HDAC9,PHF19,SPOCK2,TMCC2,CHRDL1,DMPK,CALN1,EYA1,MRVI1,NRN1,FHL1,SORBS1,KHDRBS3,CGREF1,FUT9,MTHFD2,SYT17,DNER,GGTA1P,GLRB,GNAO1,GPT2,GPM6B,GRIA1,GSN,WIF1,HLF,SCIN,CREG2,MAT2A,TM6SF1,CCDC80,N6AMT1,MYBPC1,NCAM1,NFIA,NPTX2,PIRT,ENPP2,PIK3R1,PPP2R5E,PKIA,PTN,CEP97,RGS12,MEG3,HUNK,KCNIP1,SATB1,ATXN1,SH3BGR,FHOD3,SMTN,LIMS2,LGI3,SMARCD3,SNRPN,HHIP,TIMP4,BEX4,TNNT1,TPM1,TPM2,SYNPO2,FNDC5,RBFOX3,CLDND1,REEP1,PCBP4,SSPN,ST8SIA2" Coexpression M2446 Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.56E-09 4.12E-05 2.99E-07 2.97E-06 74 244 "ACADM,FMNL2,ZNF608,ARHGAP20,AMPD3,THSD7A,RUNX1T1,LDB2,SLC16A4,REPS2,CDH2,DCLK1,RCBTB2,ZNF521,ZFP28,TOX,ARNT2,NR1D2,EDNRB,EYA1,MED12L,SCARA3,SESN1,RAB30,LPAR4,STMN2,IGF1,LRRCC1,IL6ST,KCND2,STMN1,LIFR,MAP2,MEF2C,MEIS2,MEST,KITLG,MMP16,SESN3,RSPO2,NFIA,NFIX,PBX1,PCDH9,PDE1A,PDGFRA,PIK3R1,PMP22,PRRX1,LRRN3,DIRAS2,PTPRD,PTX3,FAT4,TSPY26P,RNASEL,ZFHX4,LGR4,DZIP1,SLC12A2,SLC14A1,MTERF2,CAND2,ADHFE1,SYT11,PLCB1,PDLIM2,TCF7L2,TRIM2,ITGB3BP,TGFBR3,TRPS1,PLEKHH2,ZIC1" Coexpression M9203 Genes up-regulated in CD8 T cells: naïve versus day 8 after LCMV infection. MSigDB C7: Immunologic Signatures (v6.0) 3.90E-09 4.51E-05 3.25E-07 3.23E-06 64 200 "AS3MT,ADCY6,TMCC3,SLC12A5,ZNF608,WDR35,GPRASP2,APBB1,NT5C3B,ZFYVE28,ALDH7A1,BCL7A,PTBP2,FMNL3,CLCN4,TMEM59L,ARHGEF6,COL4A5,SLC25A27,CSNK1E,GREB1,TOX,DAPK1,DLG3,ATL1,RASGRP1,ENO2,ARMCX1,PRMT5,BAIAP2,TMEM164,UBE2E3,STAU2,ZNF512,CHL1,TDRKH,MAP4K5,BACH2,ZDHHC15,CELF5,IL6ST,SMAD1,ADAM11,AFDN,SPATA6,PRKCB,MAPK7,BEND5,GTDC1,SATB1,ST6GAL1,DZIP1,TET1,TNIK,CAND2,BEX1,ZC4H2,FAM168A,BHLHB9,TTC3,TUBB2A,XPO1,SLC30A4,VANGL2" Coexpression M19508 Genes with hypermethylated DNA in lung cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.98E-09 4.60E-05 3.29E-07 3.27E-06 105 390 "C1QTNF1,BEGAIN,AMT,ANK2,MAP4K3,CADPS,PDE8B,ATP2A2,PROM1,LDLRAD4,CFAP410,CANX,RGN,ARHGEF1,SYNGR3,CD81,CACNA2D2,ARHGAP22,SLIT2,COG1,GAL3ST1,SEC31B,CSF1,LRIG1,LRRC3B,PDE4DIP,PYGO1,SPOCK2,CNIH3,DTNB,CNNM1,RASGRP1,ELAVL2,RASGRP2,EPHA5,RCSD1,SH3YL1,DLC1,FECH,OLFM1,FGF11,ST6GALNAC3,TPPP3,GABRA2,GALNT15,FAM184B,ATP8A2,PRLHR,RAPGEF4,GRM7,FAM107A,HTR5A,SOWAHA,ITPKB,KCNA4,KCNJ3,KIT,RSPO2,NEFM,NELL1,NFIX,NME4,ENPP2,PENK,PHKG1,RETREG1,PLCB2,PLTP,NKAIN4,ZIK1,RBBP6,HKR1,MRAP2,ZNF671,STK32B,RYR3,LRFN5,SOX1,ZCCHC24,LHPP,NACAD,SULF2,AJAP1,NECAB1,ADAMTS17,TACR1,EXOC7,VWC2,PCDHGB2,PCDHGA3,VWCE,TF,TLL2,CSMD1,PIK3R5,ZNF154,ZNF177,ANKS1B,SPIRE1,MEIS3,RGMA,PARP6,STOX2,PRDM8,SLC17A6" Coexpression 18199535-SuppTable1 Human StemCell_Amundson08_990genes GeneSigDB 4.31E-09 4.98E-05 3.54E-07 3.51E-06 210 930 "ACADM,ACHE,CDC7,ADORA2A,ALCAM,AMPD3,AMPH,CDC42BPA,ANK1,ANK2,ANK3,APC,APOC2,SHROOM2,TMEFF1,ASPA,ATM,SLC4A4,ATP2B1,RIPK1,AZGP1,BARD1,MPDZ,BCHE,SYNJ1,BTK,MTMR3,C5,RAB29,CAST,HIP1R,CBLN1,CLDN10,CCNT1,RGN,SEPT7,LARGE1,CDO1,CLGN,CACNA2D2,CFL2,CHGA,CHI3L2,CHRNA4,CPNE6,FAM189A2,NIPBL,ARHGEF6,CNR1,AKAP6,COL11A2,AKAP5,CPS1,CLOCK,CRMP1,CRYM,CSF1R,CSNK1G3,PDE4DIP,RUBCN,DAPK3,DCT,SACS,DYNC1I1,NR1D2,CASP8AP2,EDN3,EDNRA,HIPK3,EGR3,PLXNC1,LPAR6,EML1,OLIG2,RCAN2,EPS8,EXTL1,ACSL4,FGF12,FOXF2,FLT1,FOLR2,USP16,STAMBP,GABRA1,GALC,IQGAP2,GPR162,CRCP,TCERG1,SPIN1,GLUL,RAB40B,GOLGB1,GPD2,GPM6B,GPR19,GRIK3,PTPRT,KIF3A,PSIP1,FAM107A,GUCY1A1,HSPA1L,ICA1,IFI16,IL6ST,JAK1,KCNA1,KCNH2,KIF5C,KLRC2,MAOB,MATN2,MBD1,MEF2C,MEIS1,AFDN,MMP16,MN1,MX1,MYL3,MYO9A,NAP1L3,NEK1,NF1,NFIX,NRCAM,NTRK3,NUCB1,OLR1,OXTR,PBX1,PCSK2,CDK18,PDE4A,PDE1B,PDGFRA,PIK3R1,PLCB2,PLXNB3,PMP22,SEPT4,POU6F1,MED1,PRKAB2,PKIA,MAPK4,RELN,PTH1R,PTN,PTPN13,PTPRD,PTPRN2,PTPRZ1,RAD52,RAP1GAP,ARID4A,RBBP8,RDX,RET,REV3L,RGS3,RGS4,ROBO1,RYR1,ATXN7,SCN8A,SUPT20H,HSPA4L,SH3BGR,SEC31A,SLA,SLC1A3,SLC2A5,SLC12A2,SLC22A4,CPEB4,SNRPN,PALLD,CAND2,SPP1,TROVE2,POPDC3,FAM200B,LEFTY2,TGFBR3,TIE1,TJP1,TRIO,TSN,TSC2,SSBP2,CADM1,UBE3A,USP1,VSNL1,XRCC4,ZNF23,SLC26A10,ZNF177,ZNF184,SCG2,WNK2,HNRNPA3,JMJD1C,FXR1,IFT88,AP3B2,ST8SIA2" Coexpression 20421987-TableS1 Human Lung_Hou10_1067genes GeneSigDB 4.39E-09 5.08E-05 3.57E-07 3.55E-06 171 724 "NCKAP5,CCDC85A,ADRB2,HECW2,ADGRF5,SPARCL1,SEMA6A,SRPX,AQP4,ARRB1,ASPA,TMEM108,ATP1A2,DOCK11,CFLAR,DST,IL33,CA4,CAPN3,PRC1,LDB2,REPS2,LRRFIP1,CDO1,CACNA2D2,CFL2,CHI3L2,MS4A7,JAM2,SLIT2,CLU,FAM189A2,QKI,FHL5,ARHGEF6,CNR1,ABI3BP,CREB5,AKAP12,ANKRD44,ARHGEF10,CX3CR1,ECE2,DOCK4,MYADM,RASSF2,DAPK1,SPOCK2,ZEB2,CHRDL1,DMD,DPYSL2,ECM2,EDN1,EDNRA,EDNRB,FRY,PCOLCE2,EML1,CALCRL,EIF1,ERBB4,HSPA12B,F8,ABCA8,EFEMP1,DLC1,FGR,FHL1,FOXF2,FOXM1,ATP13A4,SORBS1,GAB1,HIGD1B,GHR,LYVE1,HPGDS,FERMT2,GPT2,GPM6A,GPM6B,LILRA2,RAPGEF4,TPPP,GRIA1,ADAMTS8,GUCY1A2,FAM107A,GUCY1A1,WIF1,IRAK3,HBA1,TOX2,HLF,VSIG4,NEGR1,IL6R,IL6ST,ZNF385B,KCNK3,LAMA2,LIFR,LMO2,MAOB,MSR1,MT1M,NTRK3,OLR1,OMG,PCDH9,ANLN,PMP22,PSAT1,SPATA6,FAT3,PTPRB,PTPRG,ACSS3,FAM184A,RASGRF1,VEPH1,CRTAC1,RFX2,ROBO2,TMEM100,GLDN,RPS6KA2,LRRK2,SCN4B,SCN7A,SH3GL3,MAGI3,PREX2,PKNOX2,SLC11A1,SLC14A1,SLC15A2,SLC22A4,LIMCH1,PDZD2,SPP1,TACC1,KAZN,TAL1,PDLIM2,SYNE1,DOCK9,TEK,ZFPM2,TGFBR3,HHIP,TIE1,NACC2,TLR4,TMPO,TNS1,PIK3R5,TPD52,SYNPO2,PLEKHH2,KCNT2,ZBTB16,ZFAND5,ADAMTS9,CAB39L,PLSCR4,FAM13C,ADAMTSL3,MSRB3,NHSL1" Coexpression 18537972-TableS3 Human Leukemia_San Jose-Eneriz08_772genes GeneSigDB 4.53E-09 5.24E-05 3.67E-07 3.64E-06 159 662 "RALGAPA1,CLK4,ADCY8,ADD3,AP2A2,NR0B1,SPARCL1,SEMA6A,SYT13,APBB2,DGKD,BCAS1,AQP4,CDC14B,ARHGDIG,ASCL1,ASPH,RASL11B,ALDH4A1,EIF4G3,N4BP2L1,AZGP1,SYNJ2,SCAPER,BAIAP3,CALM1,KALRN,CAMK2B,SLC25A14,HIP1R,CBLN1,CBS,CCKBR,MTMR7,ARHGEF2,DLGAP2,SOCS6,SLC22A6,NRXN1,TJP2,PCYT1B,COL11A2,CSF1,CHD5,PPP6R2,ARHGAP24,HDAC4,MAML1,BRINP1,EXOG,MED12,RCAN1,EDIL3,CELSR3,PHF20L1,SUGP2,EGFR,ELAVL3,SRRM1,EFS,ZNF391,EYA1,CACNG2,TUBB4A,ATP8A1,ZMYND10,ZNF589,CAMSAP1,SYNCRIP,AKAP3,ARFGAP2,GAP43,GART,SRCAP,GFRA1,LYVE1,SPIN1,OS9,GOLGB1,GRK4,GRM2,AP4S1,NCKAP1L,KLF12,HMGCL,HNMT,DHX35,HSP90AA1,TJAP1,INPP5B,CDH20,KCND1,PACRG,ADAM22,MSR1,FXYD7,NDUFA5,NF1,NTRK3,PAH,PIK3R1,ZFYVE21,MTRF1L,MAPKAP1,TNPO2,POLG,PPP1R1A,PPP3CC,PTN,ATG16L1,RASGRF1,TRIM68,ARHGEF10L,NUDT11,PBRM1,KIRREL1,ZNF671,FOXRED2,SATB1,FNIP1,SUPT20H,TRA2B,R3HDM2,RAB3GAP1,SLC11A1,ATF7IP,PALLD,KDM4B,TSNAXIP1,SOX11,ZSWIM8,SPTAN1,NFASC,ATP10B,TROVE2,SSTR2,ABCC8,ARHGEF9,SYT5,EXOC7,IQCE,TCF7,ARHGEF12,SIK3,TEK,ZFPM2,CHST8,TGFBR3,TK2,TRIO,PDSS1,TMPRSS5,BEST1,ZNF45,ANKS1B,NAV2,SNX27,WIPF2,ZNF37BP" Coexpression M15107 "Genes up-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.96E-09 5.74E-05 3.98E-07 3.96E-06 89 315 "RBM10,KIAA1211,C1QTNF4,LRCH2,ASPH,DPY19L3,PROM1,DST,WASF1,MAP7,SOCS6,B4GALT6,ARHGAP22,SLC25A27,ZNF521,FAM171B,CRHBP,TCAF1,DAPK1,SCRN1,ARMCX2,CEP170,RHOBTB1,SPOCK3,SV2A,CHRDL1,CALN1,KCTD3,ARMCX1,PRMT5,FHL1,ZBED3,ATP2C1,KHDRBS3,ZMAT1,IQGAP2,GATM,ADAM28,HPGDS,ADGRA3,GUCY1A1,MUM1,HLF,HMGCR,NEGR1,DOCK7,KIT,STMN1,SMAD1,MEIS1,MEST,WDR49,NAP1L3,NASP,PDE1A,CYTL1,FAM98B,KCTD15,FAM216A,SCHIP1,TUG1,RDX,RAVER2,BAALC,MEG3,SCN3A,ANKRD6,PREX2,BTBD3,LIMCH1,PDZD2,SPART,POGZ,ZNF302,NKAIN2,PLCB1,SYPL1,ANKRD28,OBSL1,CBX5,TRO,SSBP2,ZNF709,ZNF711,MICU3,TMEM163,ITM2C,MSRB3,FRMD6" Coexpression M768 Genes commonly up-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.30E-09 6.13E-05 4.23E-07 4.20E-06 39 98 "NDRG2,SEMA6A,BIN1,PKP4,NCOA1,PTBP2,CACNA2D2,FOXN3,CNR1,PPP1R16B,DMPK,PLXNC1,NCALD,PIPOX,EYA1,TPPP3,ARPP21,PCDH17,GNAS,TUBB2B,KCNN3,MYCN,NCAM1,NHLH1,NRCAM,PDE2A,PKIA,PCMTD2,RYR1,SIRT2,SCN3B,SOX11,POGZ,SYNE2,COBL,POPDC3,ZNF106,HEY1,TMOD1" Coexpression 15361855-SuppTable1 Human Ovarian_Donninger04_1191genes GeneSigDB 5.39E-09 6.24E-05 4.27E-07 4.24E-06 217 970 "ABR,ADD3,AXIN2,BRAP,AP2A2,MTUS1,C1QTNF1,C1QTNF3,ALAD,AMPD2,BIN1,OGT,ANK3,MAP4K3,PARG,APAF1,APOC1,CDK10,ARHGDIA,ZBTB10,BARD1,BBS2,BMP7,DST,MTMR2,AP1M1,CACNA1A,CALB2,PTBP2,CAST,CLDN10,LONRF2,CDC42,LRRFIP1,L3MBTL4,SLIT2,TPP1,ARMC8,SLC25A27,IFFO1,AHCTF1,TCEAL2,ACBD5,CP,CREM,RBM39,LRIG1,LRRC3B,ARHGEF10,PDE4DIP,NOS1AP,BOC,DOCK4,HDAC9,FGFR1OP2,HDAC4,TOX,IP6K1,CTIF,GIT2,DBN1,GSDME,ARNT2,DMD,CDON,DPYSL2,ARRDC4,DTNA,MAMLD1,EBF1,EDN1,SEMA3D,PCOLCE2,ERBB4,SPEG,ARMCX1,ABCA8,EFEMP1,CEP78,CHST15,FECH,AMOTL2,FHL1,FLNC,NBEA,CELF1,STAU2,SARAF,GABBR1,FAM120B,GALC,RAPGEF6,ZNF274,WASF3,GHR,GLRB,GLUL,OS9,PSRC1,GPD2,GSTM5,GUCY1B1,RASSF8,ZHX1,PACSIN2,FRMD3,JAK1,KCNB1,ARHGAP12,SMAD1,LYPLAL1,MBP,MDM4,MEIS1,MEIS2,POC1B,MSRA,ZNF92,NFIA,DDR2,CLDN11,GPR137C,PALM,PDE3A,PDGFRA,PFKP,PIK3C2A,PMP22,ING3,RETREG2,EPB41L4B,PILRA,CRLS1,PPP2R5C,PPP3CB,SYTL2,DEF8,PTK2,PTN,PTPRG,TUG1,RNASEL,RNH1,SETD5,MYH14,ELP2,SEMA6D,ATXN1,SFPQ,PUF60,PREX2,BTBD3,ZNF430,SEPHS1,EPC1,SMARCD3,TTC17,SNCA,LMBRD1,TMCC1,SON,KDM3A,ZC3H13,TSPYL2,SPART,NFASC,SRPK2,ZNF302,NXT2,NEK4,FGD4,VPS13A,ADAMTS17,ANKRD28,ATP11A,TACC1,ROBO3,CAMTA1,KIAA1107,IQCE,TPCN2,PCDHGC5,DOCK9,PCDHB10,OBSL1,PCDHAC2,PUM2,TNS2,CYB561A3,ZFPM2,TMPO,KCTD2,TPD52,TPM2,TPM3,TRO,TRPC1,TRPS1,ZMYND8,FLRT2,USP1,SF1,PLPP4,CRB2,ZNF138,REEP1,SPIRE1,MAP3K12,LRP8,STOX2,MDH1B,PLSCR4,FZD3,JMJD1C,VANGL2,TTC7A,FXR1" Coexpression 19074870-SuppTable4a Human StemCell_Harris08_490genes GeneSigDB 6.35E-09 7.34E-05 5.00E-07 4.96E-06 106 398 "SERPINA3,ACHE,ACLY,NDRG2,APP,ARRB1,ATP1A2,RIPK1,BCHE,NRP2,ST3GAL5,WASF1,CAPN3,CDC42,RAB3C,SLIT2,FBXO7,MAP4K4,ARHGEF6,CNTN1,COL9A1,COL9A2,COL9A3,COL11A2,MYRIP,NRG2,HAPLN1,ABCG1,CSNK1E,GPRASP1,DRD1,SEMA3D,ELN,EPHB1,ERBB2,TUBB3,FGF1,FGFR3,FOXM1,FLT1,FYN,DKK3,ADAM28,C1QL1,GJB1,GNAO1,GP1BB,GRIA1,GRIA4,GSN,WIF1,HAS2,KCNK1,MBP,SYT9,CHST6,MMP16,MMP17,CD200,GIT1,MYO5A,NFE2L2,NKX2-2,CLDN11,P2RX7,PAK3,PCSK2,PDGFRA,ENPP2,PKD1,PLCD1,FXYD1,PLP1,PLXNB3,PPP2R2B,PPP2R2C,PTPA,SYTL2,RET,RLBP1,ROBO1,S100B,MAPK12,SCG5,SH3GL3,ABLIM3,SLC8A1,SLC12A2,RIMS1,SNAP25,SNCB,SNCA,SOX10,SPP1,SYT4,DOCK9,TNS2,HHIP,HEY2,TPD52,TRO,UGT8,MICAL1,XPO1,ANKS1B,NUP214" Coexpression 19074828-TableS4 Human Leukemia_Agirre08_1149genes GeneSigDB 7.25E-09 8.38E-05 5.67E-07 5.63E-06 172 734 "SYN3,ACHE,ADCY8,BRAP,OSBPL1A,DOC2A,CDC42BPA,APBB2,BCAS1,SEMA4G,MADD,ARHGDIG,ASCL1,PDE8B,BCHE,FGF17,CFLAR,ARHGEF7,FUBP1,CA4,NGB,SLC25A14,CCK,MTMR7,INA,CD86,NEURL1,ARHGEF2,CDC27,NDST3,ZFYVE9,NRXN1,QKI,HOMER3,COL4A5,TBPL1,NCOR1,SNCAIP,OSBPL3,ATRNL1,DZIP3,CTH,GREB1,ARHGEF4,CTNND1,ECE2,KIAA0408,HDAC4,TM9SF4,TBC1D5,DAPK3,BRINP1,DCC,DCT,TIAM2,DNM1,DMPK,ABCC9,EDIL3,EDNRB,KLHL5,CELSR3,AASS,EIF4G2,IRAK4,ANKMY1,CACNG2,ATP8A1,ZMYND10,FER,FGF12,CAMSAP1,POMT1,GABRA4,GAP43,DISC1,GART,RND1,GRIA2,NR3C1,GRM1,GRM5,GSTM5,AP4S1,HMX1,TLX1,HSD17B1,INPP5B,KCNJ10,KCNQ3,KIF5C,PACRG,PTOV1,MYT1,FXYD7,NAP1L2,NDUFA5,NFIX,NOVA1,NTRK2,NTRK3,OCRL,PC,PCDHGC3,PDE4A,PDYN,PFKFB4,ABCB1,PIK3R1,PKD1,EPN1,MTRF1L,MAPKAP1,PMS2,PPP3CC,MASP1,BCAS3,PTHLH,PTN,PTPRD,RAP1GDS1,RBBP6,GAL3ST4,RGS12,S100B,DZIP1,SLC12A2,ATF7IP,SMARCA4,SNAP25,KIF13A,SNRPN,TNIK,FNBP1,UNC5B,ZNF423,SPTAN1,SPTB,FCHO1,MAPK8IP3,ABCC8,ARHGEF9,PLCB1,TACR1,TAF6,TCF4,SATB2,PUM2,PCDHA5,SLC35G2,ACTR6,TLL2,SMUG1,TRIO,AMACR,TRPC3,TMPRSS5,TSC2,UBE3A,USP1,VIPR2,ZNF23,TRIM9,ZNF45,SPHK2,EVI5,LMAN2L,RNF103,ADAMTS9,SEMA3B,PAK5,SENP7" Coexpression 18565887-TableA8 Human StemCell_Murat08_25genes GeneSigDB 7.42E-09 8.59E-05 5.76E-07 5.72E-06 14 18 "BBOX1,AQP4,SLC25A18,DTNA,F3,ITPKB,MAOB,NDP,P2RY1,PAX6,SLC1A3,MLC1,NR2E1,HEPACAM" Coexpression 19185848-TableS4 Mouse StemCell_Read09_300genes GeneSigDB 7.90E-09 9.13E-05 6.09E-07 6.05E-06 68 221 "APC,PPFIA3,SEMA4G,MADD,CDK5R1,ARHGEF7,CACNB4,CAMK2D,EVI5L,LRWD1,CHGB,FADS2,DNAJB5,RNF14,SCRN1,DNAJC6,SV2A,SRGAP3,DLG2,PLEKHA1,APC2,CINP,GABBR1,DNER,GPR162,UBE2QL1,KCNK2,KCNQ2,KIF5C,KLC1,L1CAM,MAPT,POC1B,MRPL42,PLCD1,PACSIN1,SH3KBP1,MINDY2,PPP3CB,PKIA,MAPK10,RIPOR1,RTN1,STX1B,PPM1E,WDR47,CPEB4,EPC1,TNIK,ZBTB43,NFASC,STXBP1,SYT11,SYN1,SYT1,TCF4,GPRIN3,TRIO,TTC3,SLC35A4,NDRG4,REEP1,MAP3K12,GDPD5,STMN4,NELFE,PAK5,NETO2" Coexpression 19235837-TableS2a Human Pancreas_Cavard09_736genes GeneSigDB 8.00E-09 9.25E-05 6.13E-07 6.08E-06 135 544 "FMNL2,ADCY2,AXIN2,SLC24A4,TBC1D14,OSBPL6,GPRASP2,LRCH2,PKP4,ALS2,CDC14B,PDXK,CADPS,ASGR1,RASL11B,EIF4G3,ATP1B3,BBS2,MPDZ,BMP7,ST3GAL5,CA4,SLC25A14,SYT6,CAST,MAGI1,CHN1,CNOT8,JAM2,NRXN3,FADS2,HECTD1,MAP4K4,NECTIN3,SNCAIP,FEZ2,DZIP3,MATR3,RIMS3,SCRN1,DBN1,MYEF2,SACS,ARNT2,DNAH9,DMTF1,DYRK1A,DNM1L,TSPAN5,EDN3,KLHL5,EFNA3,ASB3,EIF4G2,COPS4,STARD3NL,TUBD1,STX2,ARMCX1,POLK,FAM49B,ATP6V1H,FYN,STAG2,CHL1,CAB39,NCKAP1,MALT1,NTNG2,STARD3,TMEM25,MAP4K5,WIF1,MUM1,ACOT7,HMGB1,GABARAPL2,CPT1C,HSF2,LIX1,LAMA2,LSAMP,MAP6,CD200,MSRA,MT3,MYO9A,NAP1L1,NDUFA5,NFIA,NPTX2,OCRL,ENPP2,SNX10,PKM,PPARA,CRLS1,PPP3CC,PRKCZ,SLC26A11,SLC22A23,PXK,PTPRG,RNASEL,SLC20A2,CPEB4,SMARCA4,OGDHL,CDK5RAP2,SON,NMNAT2,THSD1,NKAIN2,SS18,ROBO3,CAMTA1,TCF7,TRIM2,WDR7,PSD3,TGFBR3,HEY1,ACTR6,HEY2,TNFRSF1B,AMACR,TMEFF2,USP1,ZNF184,ZSCAN26,HPS4,NAV2,ITM2C,PCBP4,GOPC" Coexpression M1726 Transcripts showing subcellular localization only to proximal dendrites in the adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.58E-09 1.11E-04 7.29E-07 7.24E-06 21 37 "ANK2,BSN,INA,CHGB,SULT4A1,DNAJC6,NSG2,GPD1,HPCA,KIF5C,MAP2,NNAT,NRGN,CDK14,NECAB2,RPH3A,SNRPN,MTCH1,PLPPR2,SLC17A7,NETO1" Coexpression M5909 Genes involved in development of skeletal muscle (myogenesis). MSigDB H: Hallmark Gene Sets (v6.0) 1.02E-08 1.18E-04 7.65E-07 7.60E-06 63 200 "ACHE,ACTN2,BIN1,PPFIA4,APP,MYOM1,CACNG1,CAMK2B,MYOM2,LARGE1,CLU,MYL6B,CNN3,PICK1,SH2B1,PDE4DIP,DMD,DMPK,DTNA,SORBS3,EFS,SPEG,FHL1,SORBS1,GAA,GNAO1,GSN,GABARAPL2,IGF1,ITGA7,KCNH1,KCNH2,KIFC3,LAMA2,MEF2C,MYH3,MYH7,MYL3,NCAM1,NOS1,PC,PGAM2,FXYD1,SCHIP1,PKIA,PYGM,RYR1,MAPK12,MRAS,SH3BGR,SMTN,SLC6A8,SIRT2,SLN,SPTAN1,ST5,TNNT1,TPM2,TPM3,TSC2,REEP1,NAV2,SSPN" Coexpression M4584 Genes up-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.02E-08 1.18E-04 7.65E-07 7.60E-06 63 200 "OSBPL1A,ALCAM,LCORL,MAP4K3,SFMBT2,BCL2L2,SYNJ2,CCNH,ABCG2,ZFYVE16,DGKG,PITPNC1,ZEB2,SACS,SRGAP3,NR1D2,GPHN,PIPOX,EZH1,ARMCX1,FGF13,SYNCRIP,TACC2,NSG1,GAB1,RAPGEF6,INPP5K,NR3C1,PRDM5,ICA1,HES5,IL11RA,KIF2A,SYTL4,SMAD1,MAT2A,MBNL1,NEFH,NFIX,CNOT4,CAMKV,EPB41L4B,MED1,PRKACB,PRPSAP2,RBBP8,RNF220,WLS,CLIP1,HKDC1,TET1,FAM126B,ERBIN,ANKRD28,DDHD2,TCF4,SLC44A1,THRA,TNS1,UCHL1,SLC30A4,ST7,FRMD6" Coexpression M16407 Genes in the expression cluster 'LT-HSC Shared': up-regulated in long term hematopoietic stem cells (LT-HSC) from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.12E-08 1.29E-04 8.30E-07 8.25E-06 85 301 "KIAA1324,SPARCL1,KIF6,AQP4,MYOM1,MPDZ,DCAF5,SCAPER,MAP7,LDB2,C1orf52,LARGE1,FOXN3,JAM2,RAB33A,CNTN1,ARHGEF10,PDE4DIP,EDRF1,INTS1,HP1BP3,SRGAP3,DNM1,EGR3,PLEKHA1,ELAVL4,EPB41L2,EPHA5,SLC43A2,NSRP1,SLC9B2,SGIP1,SYT3,NBEA,GAA,ZMYND11,STARD10,DNER,GLS,FUT10,EML4,PCLO,HLF,SYNPO,KNDC1,MAG,MAPT,MARK1,MATN2,CHIC1,ADAM22,PCDH9,PRRX1,PROX1,PTPRZ1,BEND5,SLC6A15,DUSP15,TTLL7,DCUN1D2,PAQR6,STX1B,CCDC112,ATXN1,URGCP,RAB3GAP1,SLC12A2,LGI3,ZFP1,IFT122,SPATA7,FAM168A,SYN2,DOCK9,TIE1,TNS1,RPRM,EIF4ENIF1,CLEC2L,SF1,FMN2,ANKS1B,PLSCR4,DOCK8,AAAS" Coexpression M1410 Cluster 4: genes down-regulated in B493-6 cells (B lymphocytes) upon serum stimulation but not affected by MYC [GeneID=4609]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.12E-08 1.30E-04 8.30E-07 8.25E-06 167 712 "ABAT,ASPHD1,ACADM,ADCY8,ADD3,CDC7,KIDINS220,OGT,PPFIA1,PKP4,ANXA7,PARG,APAF1,GAS7,ARSE,EIF4G3,ATP2A2,MTMR9,BACH1,BCL7A,SGCE,LDLRAD4,CACNA1E,CALM1,KALRN,CANX,CAST,CCK,KRIT1,CCNH,SLC16A4,CDH8,UBE2L6,RCBTB2,SRSF11,SOCS6,RCHY1,NSL1,NECTIN3,AKAP12,LRIG1,ATRNL1,CTH,ZFYVE16,SIRPA,YTHDC1,ZEB2,ELMO1,GSDME,DDX46,RABGAP1L,DOCK2,ABI1,ATN1,GNE,DYRK1A,E2F5,EDIL3,RASGRP1,YAF2,SH3GLB1,PLXNC1,EIF5,USPL1,EIF1,EPHA5,SRRM1,EFS,VPS26C,ACSL4,TAOK3,SCML2,ATP8A1,FDFT1,SEC24B,NPTN,ZMYND11,COPS8,GLUL,CBX1,LILRB4,GPM6A,PSIP1,HPS5,NCKAP1L,ELOVL5,GABARAPL2,HMGCR,HPCA,IFI16,IL6ST,KLHL23,KTN1,LAMP2,SMAD1,MBNL1,ADAM22,MYBPC1,MYH6,MYL3,NAP1L1,NDUFA5,NFE2L2,NHLH1,NOS1,NRGN,PCMT1,CDK18,PIK3CD,FTO,PMP2,PPM1B,PPP3CA,PPP3CC,PRKACB,PRPH,PRPSAP2,SNRK,PTPN13,PTPRG,PEX2,RAD17,RAD52,ARID4A,REV3L,RGS4,CLIP1,SCP2,SFPQ,TRA2B,SMARCE1,RBM34,USP33,MYCBP2,CLASP2,NXT2,CEP68,PRRC2C,SYPL1,COBL,ANKRD28,FAM208A,FBXW11,TCEA1,DMXL2,TCF12,WASHC4,WDR7,PSD3,ITGB3BP,THRA,R3HDM1,TP53BP2,TPD52,RUNDC3B,SSBP2,UBC,UBE3A,VLDLR,WNT7A,TRIM9,ZFAND5,EVI5,KCNAB1,MPPE1,RTN4,HNRNPA3" Coexpression M1796 The glioblastoma multiforme (GBM) plasticity signature: genes up-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.13E-08 1.31E-04 8.34E-07 8.29E-06 74 250 "SPARCL1,CNIH2,APLP1,VAT1L,BCAS1,TMEFF1,ASPH,BMPR1B,RAB29,CAMK2D,VXN,PRC1,CD38,LRRFIP1,CRLF1,RAB33A,CLU,ZFP28,CP,CSF2RA,CHRDL1,EDNRB,F3,TUBB3,SPSB4,DPYSL4,SMC2,CHL1,GABRB1,MTHFD2,CPLX2,ALDH1L1,CSDC2,DBF4,GNAO1,GPD1,GPD2,GPM6A,CIT,ACOT7,MBP,SCG3,TAGLN3,NASP,NRCAM,OMG,CLDN11,PDGFRA,PFKP,ANLN,SDK2,NXPH1,PPP2R2B,PRKAR1B,PSD,PTPRD,RLBP1,TMLHE,ROBO2,SLC6A11,SPP1,BEX1,SMOC1,NCDN,SYT4,VWC2,TRIM2,TIMP4,TMOD1,TMEFF2,UGT8,USP1,WNT7A,CADM2" Coexpression 20860821-TableS5 Human Pancreas_Rosero10_1018genes GeneSigDB 1.26E-08 1.46E-04 9.22E-07 9.16E-06 178 771 "NDRG3,NDRG2,PLEKHG5,ADORA1,USP35,AMPD3,FGD2,DGKZ,ALS2,CPNE5,MADD,STK33,ZBTB10,ZNF583,SLC2A11,CFLAR,FOXK1,CACNA1D,CALB2,CAMK2D,HIP1R,CCKBR,RGN,ARHGEF1,ENTPD6,REPS2,MAGI1,NUMBL,CHGA,CLCN3,TJP2,PCYT1B,SUMF2,COL11A2,TCEAL2,RTTN,CDC42BPB,ANKRD44,AATK,BOC,GAPVD1,KIAA0513,RASSF2,DBT,PITPNC1,SPATA2,DMPK,SLC12A6,ATN1,ST8SIA3,SEZ6L2,FRY,OPTN,APH1A,MBNL2,PLEKHA1,EPB41,RASGRP2,KCNMB2,TMEM74,PIPOX,OLFM1,FGFR1,SEC23B,DPYSL4,KHDRBS3,STAG2,GABBR1,ZNF274,STARD10,SESN1,DHRS4,GRIN2C,GSN,KIF3A,COQ10A,WIF1,BACH2,ACOT7,IDH3A,TJAP1,INSM1,ITGA7,KCNMA1,GATD1,KIFC3,LAMP2,MAG,CD200,STK32C,TAGLN3,MYO5A,NFIA,CNOT4,KCNK10,PDCD2,ZDHHC8,SERPINI1,CAMKV,PIK3C2A,ZFYVE21,EPN1,STRN3,PPP2R2B,PKN2,MAPK9,SLC26A11,GDPD1,ZSCAN32,PTPRN,PTPRN2,RIPOR1,ROGDI,ARID4A,RDX,PRIMA1,SNX22,EPHA10,FBXW7,SPIN3,ZC3H14,GALNT10,ASRGL1,MRAS,HSPA4L,SH3BP2,MAGI3,CHD9,BCAN,CCDC92,FAM214B,ZNF430,SIRT2,GKAP1,SMARCA4,SNAP25,EMC1,DBNDD2,IQSEC2,SSTR2,NXT2,SEPT8,SULF2,SYNE2,ARHGEF9,VPS13A,PLCB1,SYN2,PJA1,IQCE,DMXL2,TCF7,DOCK9,SLC35G2,ATP13A2,ZFPM2,LEFTY2,THBS4,THRA,ZFP91,TNS1,TPD52,TPM3,HIRA,UBTF,UCHL1,DNAJC12,TOM1L2,ZNF23,ZNF24,POLR3H,DPYSL5,RNF103,MDH1B,CAB39L,WNK2,MARCH8,LAS1L" Coexpression M253 Genes whose expression in suboptimally debulked ovarian tumors is associated with survival prognosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.57E-08 1.82E-04 1.14E-06 1.13E-05 127 509 "ADGRF5,SPARCL1,SPOP,AMH,APC,ADAM15,DST,SCAPER,MYRF,THSD7A,CAMK2A,RUNX1T1,CCNH,ARHGEF1,ARHGEF2,SEPT7,CCPG1,SRSF11,JAM2,NMT2,ABCG2,HOMER3,AKAP7,ARMC8,SNCAIP,CSF1,FEZ1,ARHGEF10,PHF14,GPRASP1,HDAC4,ZFYVE16,HEPH,FBXL5,G3BP2,DLG3,GNE,DTNB,ECM2,EDNRA,SUGP2,EPS8,DENND4A,F8,ABCA8,EFEMP1,BAIAP2,DPYSL4,CGREF1,GATM,SESN1,PCDH17,RND1,COPS8,GLS,RAPGEF1,ADAMTS8,GSTM5,IRAK3,ATXN2L,ACOT7,HMGCR,HMX1,IL6ST,KCNC2,MAOB,MATK,MEF2C,NBL1,ODF2,CDK18,PDE1A,PDE4A,PDGFRA,ENPP2,CDK14,PIK3R1,CCSER2,EPN1,TNPO2,PPP3CA,PPP3CB,VPS13C,PTPRD,PTPRN2,RAD17,CCDC40,FAT4,REV3L,MYH14,ATP8B4,RPS6KA2,SBF1,FNDC3A,SLC12A4,CDK5RAP2,LIMCH1,PDZRN3,SPATA7,ZCCHC24,CDK19,SPART,EPB41L3,SS18,FCHO1,MAPK8IP3,EXOC7,IQCE,ZEB1,SYNE1,PSD3,OBSL1,SIRT1,CHST8,LEFTY2,TIAM1,METTL3,TRPC1,VAV1,VAV2,KCNK12,USP32P2,ZBTB16,KCNAB1,PDSS2,ADAMTSL3,AAAS" Coexpression 18593951-TableS3 Human Ovarian_Bonome08_572genes GeneSigDB 1.58E-08 1.83E-04 1.14E-06 1.13E-05 126 504 "ADGRF5,SPARCL1,SPOP,AMH,APC,ADAM15,DST,SCAPER,THSD7A,CAMK2A,RUNX1T1,CCNH,ARHGEF1,ARHGEF2,SEPT7,SRSF11,JAM2,NMT2,ABCG2,HOMER3,AKAP7,ARMC8,SNCAIP,CSF1,FEZ1,ARHGEF10,PHF14,GPRASP1,HDAC4,ZFYVE16,HEPH,FBXL5,G3BP2,DLG3,GNE,DTNB,ECM2,EDNRA,SUGP2,EPS8,DENND4A,F8,ABCA8,EFEMP1,BAIAP2,FOXO3,DPYSL4,CGREF1,GATM,SESN1,PCDH17,RND1,COPS8,GLS,RAPGEF1,ADAMTS8,GSTM5,IRAK3,ATXN2L,ACOT7,HMGCR,HMX1,IL6ST,KCNC2,MAOB,MATK,MEF2C,NBL1,ODF2,CDK18,PDE1A,PDE4A,PDGFRA,ENPP2,CDK14,PIK3R1,CCSER2,EPN1,TNPO2,MINDY2,PPP3CA,PPP3CB,VPS13C,PTPRD,PTPRN2,RAD17,CCDC40,FAT4,REV3L,MYH14,ATP8B4,RPS6KA2,SBF1,FNDC3A,SLC12A4,CDK5RAP2,LIMCH1,PDZRN3,SPATA7,ZCCHC24,CDK19,SPART,EPB41L3,SS18,FCHO1,MAPK8IP3,EXOC7,IQCE,ZEB1,SYNE1,PSD3,OBSL1,SIRT1,CHST8,LEFTY2,TIAM1,METTL3,TRPC1,VAV1,VAV2,KCNK12,ZBTB16,KCNAB1,PDSS2,ADAMTSL3,AAAS" Coexpression M1105 Genes down-regulated in ME-A cells (breast cancer) undergoing apoptosis in response to doxorubicin [PubChem=31703]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-08 2.13E-04 1.32E-06 1.31E-05 360 1781 "RALGAPA1,ACHE,RBM10,CLK4,C3orf14,PLEKHG5,ADD3,CDC7,HACE1,OSBPL6,TAOK1,SPOP,MRTFA,BIN1,OGT,CDC42BPA,MAP4K3,PHF12,PKP4,APBB1,APBB2,GPAM,NT5C3B,CACHD1,CASK,ARHGAP5,ARRB2,ASPH,NUMB,ATM,ATP1A2,SLC4A4,ATP2A2,ATP6V0A1,RIPK1,BBS2,MPDZ,RGS11,BCL2L2,BCS1L,DCAF5,NRP2,DST,ST3GAL5,FUBP1,MTMR3,MTMR2,CACNA1A,PTBP2,CAMK2D,CAMK2G,CCNH,LRBA,CDC27,DCLK1,LARGE1,ZNF445,MAGI1,TBRG4,SOCS6,CHM,KMT2C,RAB28,COG1,MYL6B,FADS2,FAM19A5,QKI,HECTD1,NIPBL,CNN3,CNTN1,LETMD1,AHCTF1,RTTN,ZNF521,CHD1L,CLOCK,RBM39,AKAP12,NCOR1,TENM4,FEZ2,ARHGEF10,SDC3,PUM1,BOC,MYADM,DCAF8,EARS2,IP6K1,DBN1,ZEB2,ELMO1,HP1BP3,RUSC2,COPS7A,GSDME,PARD6A,SRGAP3,RABGAP1L,MED12,NR1D2,SLC12A6,TOM1,DYRK1A,FARSB,DNM1L,TSPAN5,KLHL5,KMT5B,DCTN4,EPB41L2,GPHN,ANKRD13B,ERBB2,SPEG,PIPOX,RASL12,EZH1,ARMCX1,AMZ2,WAC,ACSL4,FKTN,STRADA,FDFT1,FECH,FER,KIAA1109,POLR1B,FGFR1,MAD2L2,UBE2E3,FOXF2,VTI1B,SYNCRIP,FOXM1,NOP56,COQ5,TMEM175,EFCAB2,NBEA,TACC2,ZBED3,USP21,TRIM16,TPK1,MPP6,FYN,NEURL4,STAG2,GAB1,GABBR1,GHDC,MTHFD2,INPP5K,GART,TUBGCP4,SESN1,AHDC1,GHR,DHRS4,BRD8,TCERG1,DBF4,SPIN1,GLI2,TNRC6A,ZNF638,CBX1,HTATSF1,GNAO1,FERMT2,GPT2,NUDT21,NR3C1,ATE1,KAT7,ZBTB45,PSIP1,MAP4K5,RASSF8,DDX19B,HLF,ELOVL5,HMGB1,HNRNPK,IGF1,IL6ST,TUBB2B,KCNK1,KIF2A,KLC1,TTYH2,LIMS1,LSS,MAP2,MAP6,MAPT,LYPLAL1,MDFI,KITLG,CD200,MRPL42,SESN3,MSRA,PTOV1,MYO9A,NAP1L3,NASP,SFR1,NF1,NFIX,NFYA,CNOT4,SMIM11A,DDR2,OGG1,OPHN1,PAK3,PBX1,PDGFRA,OLA1,PFKP,PIK3C2A,ANLN,PIK3R1,RETREG1,FTO,MAPKAP1,EXOSC10,SH3KBP1,DRAM2,PPP3CA,PPP3CC,KANSL1,PRKACB,CEP41,PRKCZ,MAPK3,MAPK8,GDPD1,NDUFS7,QRICH1,CNTLN,PTCH1,PPP2R3C,USP47,RAP1GDS1,RDX,REV3L,ERI2,ARHGEF10L,PBRM1,TMLHE,ELP2,PCMTD2,MCMBP,CLIP1,S100B,SEMA6D,ATXN2,ATXN7,SEC14L1,SOX6,CASC3,SUPT20H,SCAF8,NTNG1,MAGI3,AMBRA1,CLSTN1,SLC4A3,PPP4R3A,BTBD3,EPN2,CCDC88A,EFHD1,SLC20A2,EPC1,ZKSCAN3,CDK5RAP2,SMARCE1,IFT122,LIMCH1,LMBRD1,PDZRN3,KDM4B,SON,ERC1,SPTAN1,KIF1B,RBM26,SPART,SRPK2,CLASP2,THSD1,ERBIN,NSFL1C,KLHL7,ATP11A,FBXW11,TBL1X,TCF4,ZFP90,TCF7L2,TRIM2,TCF12,WASHC4,USP22,DOCK9,ARHGEF12,PUM2,TNS2,FRYL,TF,TMEM121,ITGB3BP,TGFBR3,SLC44A1,THRA,CBX5,ZFP91,ERCC6L2,TMPO,R3HDM1,PARD3,RBFOX2,TPD52L2,TPM3,NR2C2,TRIO,PDSS1,TRPS1,HSPBP1,TTC3,CADM1,UBE3A,PITPNB,USP1,LMF1,CLIP2,PORCN,XPO1,XRCC4,ZBTB14,ZNF142,AMZ1,ZSCAN26,SMARCAD1,CSDE1,TUBA1A,VPS35L,CAB39L,PCBP4,VANGL2,SNX14,SSPN,FRMD6" Coexpression M2706 Genes up-regulated in primary epithelial breast cancer cell culture over-expressing E2F3 [Gene ID=1871] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.87E-08 2.16E-04 1.33E-06 1.33E-05 61 194 "FAM43B,ADGRB2,CDK5R1,INA,SYNGR3,NGEF,ABCG2,RAB26,TMEM155,ATRNL1,TSPAN5,EEF1A2,RASGRP1,PCOLCE2,ENO2,RAB9B,EFS,FGFR3,MEX3B,KHDRBS3,CSPG5,GAD1,FAXC,TPPP,FAM222A,UBE2QL1,SOWAHA,KCNA6,LMO2,NAT8L,TM6SF1,NPTX1,GPR137C,TMOD2,SNX10,PTCH1,ZDHHC14,MAP6D1,RYR1,IL17RB,SH3BGR,ZFP30,SLC4A3,GKAP1,PEG10,CDK19,EPB41L3,SEPT3,SYN1,TMEM121,FBXL16,TIAM1,HEY1,HEY2,UGT8,PDIA2,ZIC2,REEP1,EML6,SLC30A4,PLSCR4" Coexpression 18172295-SuppTable3 Human Bone_Heller08_470genes GeneSigDB 1.92E-08 2.22E-04 1.36E-06 1.35E-05 103 391 "ABAT,TKTL1,ALCAM,BIN1,APLP1,CDC14B,ALDH4A1,CACNA1G,WASF1,BAIAP3,CALM1,SPAG9,CCK,SLC16A4,LHX2,NRXN1,SLC4A8,AKAP12,MICAL2,CNTNAP2,DZIP3,CTH,KIAA0513,DBN1,ARMCX2,AASS,TENM1,RASGRP2,CDKL3,TUBB3,TUBB4A,TAOK3,FER,KIAA1109,FGFR1,FGFR3,BAIAP2,FHL1,SORBS1,PDLIM5,CGREF1,CSPG5,GLDC,GLUL,GPM6A,PCLO,GSN,HBA1,HSD17B1,ITGA7,KCNN2,KHK,KIF5C,L1CAM,LIFR,MAPT,MEF2C,MYCN,NAP1L3,NCAM1,NFYA,NPTX2,NRGN,PCDH9,ENPP2,PFKFB3,ABCB1,SERPINE2,SERPINI1,PIK3CD,GPSM2,PLXNB3,PRPH,PTK2,NUDT11,RPS6KA2,RPS20,SCP2,SMPD3,SH3BGR,ITSN1,SH3GL3,PPM1E,DZIP1,ANKRD6,SLC6A8,OGDHL,SMARCD3,SNAP25,ZSWIM8,SPP1,PEG10,SYT11,SYN1,SYT1,TAC1,CAMTA1,WDR7,ATP13A2,TMOD1,TPM1,TST,SLC17A7" Coexpression M10091 Genes down-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.11E-08 2.44E-04 1.49E-06 1.48E-05 62 199 "TAOK1,GPRASP2,EPB41L5,ATP2B1,DOCK11,CANX,SPAG9,RUNX1T1,LONRF2,CFL2,SLIT2,BTF3L4,RCHY1,PREPL,SOCS5,GPRASP1,HDAC4,SPOCK2,SIRPA,BLOC1S6,GSDME,CDON,EXTL2,ARMCX1,EFEMP1,FER,FGF13,CAP2,FLNC,ZNF512,WASF3,FERMT2,PSIP1,IFI16,KPNA5,CCDC80,NELL2,NFIA,DDR2,PMP22,CRLS1,PPP2R5E,ACSS3,ZYG11B,ZNF532,PNMA8A,SOX6,DOK5,KIF1B,RGL1,TCF4,ZFPM2,TIAM1,BEX4,RBFOX2,FLRT2,XPO1,REEP1,TMEM237,SLC30A4,PLSCR4,RNF146" Coexpression 17880687-TableS5 Human Embryo_Heim07_327genes GeneSigDB 2.26E-08 2.61E-04 1.58E-06 1.57E-05 76 263 "CLK4,CSMD2,TAOK1,SPOP,PKP4,KIF1A,BACH1,CDK5R1,CACNA2D1,PTBP2,CANX,RUNX1T1,SEPT7,CDC42,JAM2,HECTD1,AHCTF1,FAM171B,CSNK1G3,TMEM170A,DBT,YTHDC1,FEM1B,FCF1,EGFR,EPB41,RTN3,FGF12,DPYSL4,NBEA,UFM1,CAB39,GCNT2,GLS,TNRC6A,ZNF638,KCNMB4,GNG4,GPD2,GRM8,RASSF8,MIER3,IBA57,LIMS1,MDM4,PPM1L,CCDC13,NFYA,CNOT4,SLC11A2,ZNF655,PURG,RC3H2,CRLS1,PTPRG,USP47,VEPH1,DCUN1D2,GSTCD,LGR4,CLIP1,RTN1,FNIP1,SGK1,CHD9,FNDC3A,PALLD,PEG10,FGD4,PRRC2C,SF1,MAP3K12,TMEM178A,SCG2,NAV2,SOCS4" Coexpression M8645 "Genes up-regulated in the nucleus accumbens (a major reward center in brain) 2 weeks after induction of deltaFosB, a FOSB [GeneID=2354] splice variant." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.42E-08 2.80E-04 1.69E-06 1.68E-05 24 48 "ASIC2,APBA2,CADPS,ARHGEF25,CCK,INA,MFSD4A,ELAVL2,OLFM1,TBR1,SEPT9,STMN2,STMN1,SMAD1,MEF2C,MOBP,NEFM,NEFH,NPTX1,CDK14,SERPINI1,FHOD3,TUBB2A,VSNL1" Coexpression M9262 Genes down-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5- BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.60E-08 3.01E-04 1.79E-06 1.78E-05 62 200 "ACTN1,ADCY6,SORCS2,OSBPL8,USP28,DGKD,SFMBT2,TMEM108,GPR146,MTMR2,MAP7,CD81,CNN3,BTF3L4,RIPOR2,DAPK1,KBTBD11,DLG4,HIPK3,RASGRP1,MBNL2,EGR3,CALCRL,EPB41L1,ATP8A1,CHST15,SESN1,KCNMB4,GPD2,BACH2,IL6ST,TUBB2B,AFF1,CD200,MYO6,NFIX,NUCB2,PDE4B,PACSIN1,PPM1B,PTK2,RASGRF2,BEND5,RGS10,SATB1,IL17RB,ST8SIA1,ATF7IP,TET1,SULF2,TCF7,ZEB1,TGFBR3,TNS1,TTC3,UBE3A,ZNF24,REEP1,PMEPA1,NAV2,PPP1R3F,VANGL2" Coexpression M5692 Genes up-regulated in comparsion of ActTregTGF versus ActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 2.60E-08 3.01E-04 1.79E-06 1.78E-05 62 200 "FMNL2,ADARB2,ARHGAP20,FAM131A,BCAS1,SHTN1,DYNLL1,RNF182,CD38,SLIT2,CNR1,HAPLN1,GDA,AATK,ACY3,ARMCX2,DLG3,DMD,FGF13,PRKAG2,PCDH11X,KCNMB4,STON1,GUCY1B1,VSIG4,LRRC75A,HTR5A,LRRCC1,BRINP3,TUBB2B,GPR62,CLVS2,KIF5C,KIT,GPR155,MEIS2,PPM1L,CD200,LAYN,GPR85,SERPINE2,PACSIN1,PPM1B,RGS12,ROBO1,RIMKLA,HSPA4L,ZNF365,SLC12A2,SOX3,C3orf70,KIAA1107,EHBP1,TIAM1,FRRS1L,DNAJC12,VAV2,ZFP41,ATP6V0E2,NDRG4,AMZ1,FRMD6" Coexpression 20161705-Table2 Mouse EmbryonicStemCell_Layden10_73genes GeneSigDB 2.77E-08 3.21E-04 1.90E-06 1.88E-05 30 69 "ADCYAP1R1,ADORA1,ADORA2A,LGR5,CNR1,EDNRB,CELSR3,ADGRA1,GABBR1,GPR162,CRCP,GPR22,MCHR1,GPR26,GPR34,GRM2,GRM3,GRM5,GRM8,GPR45,HRH3,HTR2A,GPR62,OPRL1,P2RY1,GPR85,SSTR1,SSTR2,TACR1,ADGRL3" Coexpression M6316 Genes up-regulated in macrophages: control versus Sendai virus infection. MSigDB C7: Immunologic Signatures (v6.0) 3.09E-08 3.57E-04 2.10E-06 2.09E-05 55 170 "ACTN1,ADCY6,ADD3,SNX30,OSBPL1A,SEMA6A,BBOX1,PITPNM2,USP28,TMEM108,GPR146,CDK5R1,DNAJB5,MAP4K4,ABCG1,SIPA1L1,HDAC4,TOX,DPP6,RASGRP1,CALCRL,PLEKHO1,CHST15,GABRA4,RAPGEF6,GNAS,RAPGEF4,SYNPO,LRRC75A,KCNA2,CLEC18A,ADAM11,LRP1B,PIK3C2A,TMIE,ASPDH,PACSIN1,RGS10,SATB1,SELL,ST6GAL1,ST8SIA1,TET1,SOX1,TRERF1,CLASP2,TBL1X,TCF7,TGFBR3,TIAM1,LRRC8A,TUBB2A,ZIC1,PMEPA1,JMJD1C" Coexpression M2009 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.21E-08 3.71E-04 2.17E-06 2.16E-05 92 341 "DSCAML1,GALNT13,SLC12A5,C1QTNF4,ALK,DPP10,VAT1L,CPNE5,SLC7A14,ATP2B2,CADM3,ADGRB1,HCN2,CABP7,CCKBR,CDH8,DLGAP2,CACNA2D2,CHRNA4,SLIT2,SULT4A1,C1QL2,ABCG1,RASGEF1C,PITPNM3,KCTD8,TMEM130,ST8SIA3,CNNM1,TMEM132E,FGF14,HPCAL4,FOXG1,TMEM151A,GABRA5,CPLX1,C1QL1,GPR37,STMN2,GRIK3,GRIN1,GRM7,PTPRT,IGSF21,NXPH2,HRH3,IGFBPL1,TLX1,SHISA6,SLC6A17,KCNH1,KCNK3,KCNQ2,NEFH,NELL1,NEUROD2,VWA2,HCN1,PENK,PPP2R2C,VSTM2L,SKOR1,PRKCZ,PRPH,PTH1R,PTPRN,IQSEC3,FEZF2,CRTAC1,RXRG,LRFN5,SCN4B,MAST1,SORCS3,HECW1,RAP1GAP2,CLSTN2,MESP1,STAC2,TMEM150C,COBL,CNTN2,PHF24,RALYL,TNFRSF1B,RBFOX3,SLC30A3,CA10,TMEM163,SLC17A6,DOCK8,JPH3" Coexpression M2809 Genes up-regulated in oligodendrocytes. MSigDB C6: Oncogenic Signatures (v6.0) 3.65E-08 4.22E-04 2.45E-06 2.44E-05 38 100 "LCORL,BCAS1,MYRF,HIP1R,FBXO7,GAL3ST1,IFFO1,CRYM,CNTNAP2,DCT,SEMA3D,SRPK3,SPEG,PRKAG2,USP16,DKK3,CSDC2,ZNF276,KIAA1958,GPR17,LRRC75A,DOCK7,NINJ2,PLXNB3,FA2H,FEZF2,FIGN,MAP6D1,SOX8,RTKN,DOCK10,EPN2,SIRT2,SOX10,ATP10B,PHLDB1,UGT8,WIPF1" Coexpression M2379 Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-30 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.67E-08 4.25E-04 2.45E-06 2.44E-05 42 116 "ACTN1,TAOK1,PPFIA1,ATP2B1,CALM1,CAST,LARGE1,CCPG1,CFL2,SOCS6,MAP4K4,ARHGEF6,SLC4A7,CLOCK,MAML1,ELMO1,DDX46,DMD,CPEB2,DPYSL2,DTNA,LRRC17,TNRC6A,GNAO1,NCAM1,NOVA1,USP47,ARID4A,SEMA6D,SATB1,ITSN1,CHD9,FNDC3A,CPEB4,SON,KDM3A,ADGRL3,WDR7,SSBP2,TBC1D15,XPO1,PHTF2" Coexpression M2148 Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.74E-08 4.33E-04 2.49E-06 2.47E-05 58 184 "ADARB2,FZD9,MTUS1,TNRC6C,CDC14B,TMEM263,ASCL1,ATP1A1,FUBP1,PRC1,AP4M1,CDC27,CRYBB1,CHD5,GREB1,PUM1,GPSM1,G3BP2,ARNT2,EBF1,PHF20L1,ELAVL4,EN2,OLIG2,SYNCRIP,FOXM1,TUBA8,GFAP,TOX3,GOLGB1,SOX21,INSM1,ARHGAP12,NELL2,NOVA2,NUMA1,PCDHGC3,ANLN,PLP1,PCDH18,POU3F2,IRX1,PTPRN,PTPRO,KCTD17,PGBD4,RTKN,HES6,SMTN,SOX3,SOX11,KDM3A,INKA2,HEY1,TMPO,ZIC2,ZNF184,ST8SIA2" Coexpression 15489324-TableS2 Human Messina_04_1962genes_TranscriptionFactors GeneSigDB 3.76E-08 4.35E-04 2.49E-06 2.47E-05 351 1741 "DPF1,KDM5D,ARID1A,KLHL13,NR0B1,ZNF687,ZFAT,EP400,MIER1,CASK,ARNTL,ASCL1,ZSCAN18,ZBTB10,NCOA1,ATP2B3,ZNF582,ZNF583,BACH1,ZNF599,FUBP1,ZNF555,KALRN,TRIM41,RUNX1T1,LDB2,CBFA2T2,ZMYM4,ZNF445,FOXN3,CNOT8,LHX2,KMT2C,VAX2,FHL5,TBPL1,SMARCAL1,ZNF521,ZFP28,CHD1L,CLOCK,CREM,CREB5,RNF14,NCOR1,NCOR2,TRIM69,CHD5,KIAA0040,GREB1,ST18,HDAC4,TOX,ZNF337,RIMS3,ZEB2,ZBTB24,MED24,KLHL3,ARNT2,DLX1,OLIG1,MED12,NR1D2,DMTF1,ATN1,MAMLD1,E2F5,E2F6,EBF1,HEYL,KLHL5,OPTN,YAF2,MBNL2,KMT5B,EGR3,EMX2,EN2,OLIG2,ERCC2,DENND4A,NCALD,ZNF549,ETV1,EYA1,EZH1,ZNF461,ZNF585B,ZIC4,SCML2,ZNF589,GTF2IRD2,FHL1,FOXG1,FOXF2,FOXM1,FOXO3,AFF2,TMEM175,PDLIM5,TRIM16,ARFGAP2,TBR1,ZNF44,BRPF3,ZMYND11,NKX6-2,SALL3,ZNF274,ZNF559,GBX2,SRCAP,PPARGC1A,ZNF276,TCERG1,GLI2,TOX3,TNRC6A,CBX1,INSM2,ATF7,STON1,TMEM121B,DIDO1,NR3C1,PRDM5,ZNF496,ZBTB49,ZBTB45,SOX21,PSIP1,ATOH8,CELF3,ZHX1,KLF12,BACH2,MIER3,HLF,HMGB1,HMX1,HNF4G,ZNF491,TLX1,HPCA,HSF2,IRF8,ZIC5,RBPJ,HES5,SCRT2,INSM1,LMO1,LMO2,SMAD1,SMAD9,MBD1,MEF2C,MEIS1,MEIS2,MID1,MITF,AFF1,AFDN,ZNF92,MXI1,MYCN,ZNF862,MYT1,RCOR2,NEUROD1,NEUROD2,NFIA,NFE2L2,NFIX,NFYA,NHLH1,NKX2-2,CNOT4,SETD4,ZNF713,ZNF827,PAX6,PBX1,ZNF655,ZNF426,PRRX1,POU3F2,POU3F4,POU6F1,IRX1,PPARA,MED1,PROX1,ZSCAN32,ZSCAN2,ZNF615,ZNF493,FEZF2,HKR1,TRIM68,DPF2,REV3L,RFX2,RFX3,RFX4,RFX5,ZFHX4,ZNF532,RORB,ZNF671,SOX8,KCNIP3,KCNIP2,KCNIP1,ZNF354C,RXRA,ZNF568,RXRG,ZNF331,SAFB,SALL1,SATB1,ATXN2,HES6,ZFP2,SOX6,SUPT20H,ZFP30,ARX,BTBD3,PKNOX2,ZNF430,KDM4D,ZNF334,SCMH1,ATF7IP,ZKSCAN3,ZFP1,SMARCA4,SMARCC2,DMRTC1,SMARCE1,RCOR3,ZNF415,KDM4B,SOX1,MYT1L,TRERF1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,KDM3A,ZHX3,SP2,SP4,KDM4C,ZNF423,ZBTB43,NPAS3,LMO3,ZNF621,MESP1,ZNF302,MPRIP,ZSCAN29,SUPT5H,ARC,TAF6,TAF9,TAL1,KLHL4,TBX15,ATMIN,TCF4,SIN3B,SATB2,CUX2,TCF7,TCF7L2,ZEB1,TCF12,HIF3A,ZFPM2,ZNF106,THRA,GZF1,NACC2,HEY1,CBX5,ZFP91,NR2E1,HEY2,TP53BP2,ZNF384,NR2C2,METTL3,TRPS1,ZMYND8,TUB,ZKSCAN5,HIRA,ZNF610,AMOT,UBTF,NSD2,SF1,ZFP37,ZBTB14,ZIC1,ZIC2,ZIC3,ZNF711,ZNF708,ZNF17,ZNF19,ZNF23,ZNF24,ZNF28,ZNF32,TRIM9,ZNF45,ZNF540,ZNF74,ZNF138,ZNF142,ZBTB16,ZNF154,ZNF177,ZNF184,ZSCAN26,ZNF189,ZNF195,ZNF213,ZFAND5,SMARCAD1,MEIS3,ZNF225,ZXDA,PRDM2,PRDM8,PRDM10,RNF103,JMJD1C,ZNF248,DPF3,ZNF30,LAS1L" Coexpression M2673 Genes down-regulated in HUVEC cells (endothelium) by treatment with PIGF [Gene ID=5281]. MSigDB C6: Oncogenic Signatures (v6.0) 3.86E-08 4.47E-04 2.54E-06 2.52E-05 60 193 "DPF1,SERPINA3,PPFIA4,KCNAB2,APOC1,DDX3Y,ATP1A3,ATP2B2,CFAP410,CAMK2B,ENTPD2,LOC730101,DLGAP1,GPR37L1,TAOK2,IQCK,COL11A2,NOS1AP,RIMS3,SRGAP3,SNX29,ELAVL3,LRRC23,MTSS1L,ACTL6B,FOXG1,SRCAP,GFRA2,GNAL,GPR17,GRIA1,GRM2,CLASRP,KCNQ3,MSI1,NCAM1,NELL2,NPR2,NUCB1,OGDH,PDE1B,ENPP2,PKD1,PTPRH,KHDRBS2,SLC6A15,SLC30A10,MAST1,SPTB,NPAS3,NFASC,SSTR2,ZFR2,ARC,MCF2L,SMG6,DAAM2,TRIO,UBE2H,VGF" Coexpression 17724462-TableS2 Human StemCell_Nuytten08_2072genes GeneSigDB 3.90E-08 4.52E-04 2.55E-06 2.53E-05 353 1753 "SERPINA3,ASIC1,ABHD6,METAP1D,ADAR,ADD1,ADD3,AXIN2,SLC12A5,CDC7,ADRB2,AGT,SORCS2,AK2,MARCH4,OGT,SEMA7A,PPFIA4,KCNAB2,EPB41L5,GPAM,DGKD,APOC1,API5,USP37,APP,CDC14B,RGS20,ASGR1,CAPRIN2,SLC4A4,ATP2A2,RNF182,AZGP1,BACH1,BLM,CFLAR,C5,OSGIN2,CA12,CACNB2,PTBP2,CANX,CAST,SPAG9,MAP7,PRC1,USP6,SLC16A4,SCARB1,SYNGR3,ENTPD6,NEURL1,NOG,CRLF1,UBE2L6,DIS3L,CFL2,FOXN3,B4GALT6,SLIT2,NRXN3,PPT2,CLU,DNAJB5,QKI,MAP4K4,HOMER3,SLC4A7,BAG4,ACBD5,NECTIN3,CPS1,ENTPD4,CREB5,CSF1,CSF1R,SEC24C,ARHGEF10,SOCS5,PDE4DIP,DZIP3,KIAA0040,CTH,FAM131B,MYADM,KIAA0513,CENPL,RASSF2,MATR3,KCTD8,DGKG,SPOCK2,PABPC5,GIT2,SIRPA,CNIH3,FAM107B,DLG2,ARRDC4,TOM1,DNAJB6,ABCC5,FIS1,E2F6,EDN1,ANKRD46,OPTN,RBM12,YAF2,FAM13A,ABI2,EIF5,TMEM35A,ENO2,RABEPK,APC2,EZH1,AMZ2,EFEMP1,ST3GAL6,FCGR3A,FGF1,OLFM1,ACTL6B,BAIAP2,FHL1,POLK,CAP2,AGAP3,FOXM1,ANKFY1,JKAMP,FAM49B,ATP2C1,CGREF1,DLL3,FYB1,TRAF3IP2,ILDR2,NEK6,INPP5K,GART,DNER,GBX2,GCNT2,NFU1,GHR,MALT1,BRD8,TCERG1,MAP7D2,GNAS,GPD2,TDRKH,NUDT21,GPR37,GRB10,DIDO1,GRM5,KIF3A,IL1RAPL1,ADAMTS6,GYG1,HBA1,ZHX1,PACSIN2,BACH2,HMGB1,AGBL5,HP,CPT1C,IFI16,RBPJ,IL6R,IL6ST,DIPK1A,TUBB2B,ITIH2,JAK2,KCNB1,KCNK1,KHK,KLC1,KPNA5,LAMP2,LIFR,LMO2,LSS,SMAD1,MAP2,MATN2,MATN3,MEIS2,MEST,MGAT3,KITLG,ZNF680,MSI1,MSRA,MT1M,THYN1,MX1,MXI1,NASP,NBL1,NCF2,NFYA,NPTX1,ODF2,OPA1,CLDN11,OXTR,PAH,PBX1,PCDH9,PDGFRA,PFKFB2,PFKFB4,SERPINE2,SERPINI1,PKD1,ZFYVE21,XRN1,NLE1,PCDH18,PDZRN4,TRHDE,SCHIP1,EPB41L4B,PACSIN1,PPM1B,PPP3CB,PPP3CC,PRKAB2,CEP41,PKIA,RELN,SAMD9,SYTL2,SIDT1,PTK2,PXK,ZSCAN32,PTPRZ1,PTX3,QDPR,TMEM255A,SUSD4,RBBP6,REV3L,RGS4,SLC25A36,ZFHX4,ROBO1,PCMTD2,RPL15,SPIN3,KIAA0895L,RPL38,RIMKLA,RYR3,RMI1,SAFB,SCP2,TNFRSF19,ASRGL1,MRAS,ZNF365,SLC1A3,FAM214B,ZNF430,SHANK2,SLC12A2,ZNF334,NAPB,SLC20A2,SLC22A4,CDK5RAP2,KIF13A,TMCC1,PDZRN3,GLT8D1,IZUMO4,CLASP2,COLGALT2,MESP1,ZNF302,THSD1,SS18,NXT2,ELOVL4,RGL1,KLHL7,SYNE2,ARHGEF9,SYPL1,SEMA4A,DDHD2,TBL1X,KLHL4,TCF4,TCF7,TCF7L2,ZEB1,SYNE1,ARHGEF12,TMEM121,ITGB3BP,SLC44A1,TJP1,TK2,CBX5,LRRC8A,TMPO,KCTD2,CSMD1,TNS1,TP53BP2,RBFOX2,TPM1,CDK20,NPL,TRPC1,TSN,TSC1,SSBP2,TUBB2A,HIRA,EIF4ENIF1,CCDC136,VAV2,CCDC14,LAT2,NSD2,PORCN,XRCC4,PCDH20,FMN2,ZNF177,DPYSL5,ANKS1B,DHX33,LRP8,NAV3,PPP1R3F,NELFE,PDSS2,FBXO36,NLRP3,SSPN,FRMD6,ST8SIA2" Coexpression M6746 Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.84E-08 5.60E-04 3.14E-06 3.12E-05 55 172 "SERPINA3,PLEKHG5,MTUS1,C1QTNF1,CDC42BPA,GAS7,PHYHD1,RIPK1,ADAM15,GPR146,DST,PRMT9,SGCE,TPP1,CLTC,LY86,CP,CSF3R,PLXNA4,CX3CR1,TM9SF4,FBXL5,RASGRP1,CALCRL,ETV1,FOLR2,GAB1,GALC,LYVE1,HPGDS,GPR75,TPPP,IRAK3,VSIG4,IGF1,LRRC25,KCNJ10,TTYH2,LIFR,NCF2,OCRL,P2RX7,DRAM2,MAPK8,PTPRB,ITSN1,SLC1A3,SLC11A1,DMXL2,PSD3,TMEM9,LRRC8A,NPL,P2RY12,SNX27" Coexpression M1278 Genes down-regulated in pulpal tissue extracted from carious teeth. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.65E-08 6.54E-04 3.65E-06 3.63E-05 33 82 "ANK3,LGR5,ATP1A2,CALB1,SLIT2,NRXN1,MAGI2,SPOCK3,DPP6,FGFR1,GAP43,SESN1,GHR,GPM6A,GPR37,LINC00667,TUBB2B,KIF5C,KIT,NAP1L3,PCDH9,PLCL1,TMEM255A,LGR4,ST8SIA1,PDZD2,PEG10,ZNF423,SYT1,TRIM2,TIAM1,TRPC1,ACTR3B" Coexpression 16728581-SuppTable1 Human Liver_Capurso06_990genes GeneSigDB 5.70E-08 6.59E-04 3.66E-06 3.64E-05 205 932 "SERPINA3,ACTN1,KDM5D,AXIN2,NLGN4X,ALCAM,AMPD3,BIN1,LRFN1,OGT,ANK2,EPB41L5,APOC1,BCAS1,CDK10,ARRB2,DDX3Y,ATP2A2,ATP2B2,ADAM23,ADGRB1,ADGRB2,BMP7,DST,SYNJ2,FUBP1,CACNA1A,DDR1,CAPN3,MAP7,CBR1,CDC27,ARHGAP33,LRRFIP1,MAGI1,NOG,MS4A7,RAB28,ABCG2,IQCK,IFFO1,ZNF521,HAPLN1,CSF1R,SIPA1L1,VCAN,SOCS5,PDE4DIP,CYBB,RIPOR2,HDAC4,TM9SF4,CTIF,GIT2,MYEF2,KLHL3,DLG4,MED12,FAM57B,RCAN1,EBF1,SH3GLB1,SUGP2,PLXNC1,TMEM132E,TENM1,RGS17,PCOLCE2,ELN,LRRC17,RASGRP2,ANKRD13B,RABEPK,IGSF6,RASL12,GMPR2,MRVI1,F5,CEP78,CAMSAP1,EVL,FOLR2,CGREF1,GPR153,FYB1,GAD2,NCKAP1,GPR162,GGT5,OS9,ATF7,LILRA2,TUBA1C,ZNF496,RNFT2,MAP4K5,MUM1,IRAK3,HBA1,VSIG4,ACOT7,USP54,IL6ST,IL11RA,ITGA7,ITGAV,JAK1,KLHL23,KCNK1,LMO2,GPR155,MEF2C,MEIS2,KITLG,MKLN1,MSR1,SAMD14,NUCB1,OGG1,KCNK10,PALM,PAX6,PDE2A,PFKFB3,PIK3CD,PIK3R1,ZFYVE21,HMGCLL1,MTRF1L,PMP22,SEPT4,SLC36A4,POU6F1,PTPA,PPP3CA,PRKAR1B,PRKCB,MAPK3,MDGA2,ELOVL2,PID1,USP47,RBBP6,RGS12,TMEM100,MAP6D1,WLS,CLIP1,RMI1,MAPK12,GALNT10,ITSN1,FAM102A,FHOD3,ST8SIA1,SEPHS1,CDK5RAP3,ABTB1,SMARCC2,SMARCD3,SOX15,SP2,KIF1B,TAB2,TROVE2,SST,SSTR2,PHLDB1,PRRC2C,TAL1,ANO4,KIAA0930,RPGRIP1L,PHF24,ARHGAP9,SIK3,SIRT1,TJP1,PARD3,TP53BP2,TPD52,TPM2,DOK6,TRO,TMEFF2,UBE2H,BCL2L13,RICTOR,SLC13A3,ZBTB14,ZNF74,ANKS1B,ZFAND5,NT5M,CSDE1,SEMA3B,PCBP4,MVB12B,DOCK8,RTN4,UBE3B,PAK5,JMJD1C,ZNF248,FXR1" Coexpression M8394 Genes up-regulated in dendritic cells: spleen CD8- versus brain. MSigDB C7: Immunologic Signatures (v6.0) 5.84E-08 6.75E-04 3.73E-06 3.71E-05 60 195 "ADORA1,ADRA1B,ADRB2,AGT,ABCD2,SHROOM2,BRINP2,SLC4A4,MYOM1,KSR1,SULT4A1,COL4A5,RGS6,NOS1AP,DNAH9,EPS8,REEP2,GPER1,GRIN1,GRM1,IGSF1,BRINP3,KCNJ5,KCNK1,KIF5A,L1CAM,MAN2A2,MAP2,ADAM22,SAMD14,NHLH1,NOVA1,PLCB2,PLP1,SCHIP1,POLR2F,PTPRD,RGS4,RLBP1,S100B,SCN7A,SLC6A1,SLC12A4,MAST1,IGSF9B,MAPKBP1,NPAS3,DDN,PLCB1,SYN1,ASTN2,IQCE,SMG6,SZT2,LEFTY2,THRA,KCTD2,CDK20,ZIC1,SLC30A3" Coexpression 16455954-TableS2 Human StemCell_Dekker06_439genes GeneSigDB 6.46E-08 7.48E-04 4.10E-06 4.07E-05 99 380 "ADD3,USP31,MTUS1,HECW2,AMPH,PRX,ATP1B3,DPY19L3,BID,CACNG1,CBS,CDH2,CDH8,CDO1,NMT2,DNAJB5,MAP4K4,HOMER3,LRIG1,FAM169A,GPSM1,DOCK4,DAPK3,DBN1,CEP170,FAM107B,DOCK2,EBF1,EDIL3,EDN1,PLEKHO1,VPS13B,REEP2,ABCA8,FAM198B,EFEMP1,DLC1,FHL1,SYNCRIP,DPYSL4,KHDRBS3,DKK3,RAPGEF6,GDF1,GGT5,GLS,PCSK1N,GPM6B,GUCY1A2,RASSF8,IL6ST,LIMS1,SESN3,MDGA1,MYO5A,ZNF827,PDE3A,PDE4B,CDK14,SCHIP1,MBOAT7,PPP3CA,PRKACB,PKIA,SLC22A23,PTX3,PLEKHB2,RGS3,RGS10,MYH14,S100B,SEC14L1,GALNT10,SUPT20H,ST6GAL1,PREX2,DHX30,SLC6A1,SLC11A1,SORCS3,SNCA,SMOC1,SYT1,POPDC3,TACR1,DNMBP,TCF4,CLASP1,PSD3,ARHGEF12,LEFTY2,HHIP,TRIO,UBE2H,UGT8,FLRT2,ZFAND5,PCBP4,FRMD6" Coexpression M2921 Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Brazil). MSigDB C7: Immunologic Signatures (v6.0) 6.48E-08 7.49E-04 4.10E-06 4.07E-05 61 200 "RNF157,UNC5A,SEMA6A,BBOX1,PDZD4,ANK2,ALS2,VAT1L,ZFYVE28,DNAH17,ASTN1,C1QC,CALB1,ARHGEF6,SLC35F1,PPP6R2,ARMCX2,FARSB,EDNRB,CALCRL,EN2,EPHA5,ERBB2,SEMA6C,TPPP3,TMEM151A,GGT5,ATOH8,AGFG1,HES5,ASPRV1,CHIC1,TM6SF1,SCG3,MDGA1,FXYD6,NFE2L2,NOVA1,PDE3B,CYTL1,PDZRN4,PRRX1,MINDY2,PPP1R1A,PRKAB2,CEP97,ATP8B4,SATB1,FAM102A,DZIP1,SLC4A3,BTBD3,SLC6A11,ZBTB43,DDN,STAU1,SEMA4A,MGRN1,FBXL16,ZIC2,CERS6" Coexpression M13273 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.66E-08 7.70E-04 4.18E-06 4.16E-05 68 232 "ADD3,SRPX,ASGR1,ASPH,ALDH4A1,SLC4A4,ALDH7A1,PROM1,CA4,LDB2,COL9A3,AKAP12,FEZ1,IPCEF1,CTH,ELMO1,CHRDL1,DLG2,DPP6,EDN3,SEMA3D,RGS17,EML1,NRN1,FGF13,FHL1,IQGAP2,WASF3,GFRA2,GHR,GLDC,GPER1,PCLO,HBA1,HLF,KCNK2,KIT,LAMA2,LIFR,LMO2,MATN2,LRP1B,MEIS2,MYCN,ZNF862,FXYD6,NCAM1,NUCB2,FXYD1,EPB41L4B,PRKACB,RELN,PTN,RERGL,SYNDIG1,SH3BGR,SLC14A1,ZNF302,EPB41L3,TAL1,SYNE1,TEK,ZFPM2,TGFBR3,FLRT2,NDRG4,SLC38A1,KCNAB1" Coexpression 15869706-TableS2 Human Cervical_Rosty05_814genes GeneSigDB 6.71E-08 7.76E-04 4.20E-06 4.17E-05 149 635 "AK2,BIN1,PPFIA4,APBA2,APC,GAS7,DDO,APOC1,APOC2,ASPH,ZSCAN18,AZGP1,ADGRB3,BCHE,RGS9,BTK,CACNA1G,IL33,CACNB2,CAMK2A,CAMK2B,CH25H,CRLF1,CHN1,CHRNA4,B4GALT6,SLIT2,FADS2,PCYT1B,AKAP6,COL9A3,CSF1R,VCAN,PPP1R16B,CTNND2,ST18,CYBB,ELMO1,SV2A,EXOG,EGFR,PLXNC1,SRPK3,ELN,ETV1,NRN1,FABP7,EFEMP1,DLC1,FGFR1,FGFR3,FOXO3,SORBS1,FUT9,MPP6,FYB1,FYN,GABBR1,ALDH1L1,MSTN,GK,RND1,HPGDS,GLDC,GLUL,GNAO1,GPM6B,GPER1,GRIK4,GRM8,MUM1,HLF,HNMT,IGF1,TUBB2B,ITGAM,LAMA2,LIG4,MEF2C,AFDN,N6AMT1,MYH7,MYO7A,FXYD6,NEFH,NRCAM,ODF2,PCDH9,PDE2A,PDE4B,PDGFRA,ENPP2,PFKFB2,HERC2P3,ABCB1,SNX10,ST8SIA5,PMP22,TRHDE,PPP2R5C,PRKCB,SAMD9,PTPRN2,RASGRF1,FEZF2,SLC6A15,RGS4,RPS20,MAPK12,CSRNP3,ASRGL1,FRMPD1,DOCK10,BCAN,ANKRD6,SLA,SLC4A3,SLC6A8,SLC6A11,SLC15A2,ZNF667,SMARCA4,OGDHL,SORCS3,ZSWIM8,NMNAT2,EMC1,SAMSN1,EPB41L3,SS18,FCHO1,SYT1,ATP11A,ADGRL3,TCF4,ZEB1,TRIM2,PCDHGC5,SYNE1,OBSL1,TRIO,TRO,KCNE5,LAT2,ZIC1,NDRG4,ZXDA,NAV3,CAMK1G" Coexpression M8702 Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.80E-08 7.87E-04 4.23E-06 4.20E-05 86 317 "ABAT,ADRB2,MTUS1,SPOP,BCAR3,ATP2B1,BACH1,BCL7A,DST,ARHGEF7,USP6,CBFA2T2,QKI,NIPBL,RCHY1,MICAL2,PUM1,USP6NL,EDRF1,DOCK4,GAPVD1,MAML1,ZBTB24,CEP170,SACS,RABGAP1L,DMTF1,GNE,DYRK1A,E2F5,PHC2,FEM1B,VPS13B,SUCO,FOXO3,FYN,ZNF44,AHDC1,BRD8,ZNF638,FERMT2,DIDO1,NR3C1,RBPJ,KIF2A,MEIS1,AFF1,MN1,NFE2L2,CNOT4,PTK2,REV3L,SLC25A36,SATB1,CPEB3,CHD9,FNDC3A,WDR37,BTBD3,TMCC1,DOP1A,GLT8D1,POGZ,KANK1,AJAP1,GSE1,ZC3H4,PRRC2C,VPS13A,MTCL1,WWC1,CLASP1,DOCK9,PSD3,PUM2,FRYL,KAT6B,ZMYND8,SSBP2,FLRT2,USP1,VLDLR,XPO1,NAV3,KAT6A,CERS6" Coexpression M1349 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.05E-08 8.15E-04 4.36E-06 4.33E-05 26 57 "AMPH,CRMP1,LYPD1,ELAVL3,ELAVL4,TUBB3,OLFM1,NSG2,GAP43,TUBA1C,HMX1,LIX1,STMN1,TAGLN3,FXYD6,NEFM,NNAT,NTRK2,PCDH8,PRRX1,PRPH,RIMKLA,RASA3,LIMS2,SYT4,MTCH1" Coexpression M6110 Genes down-regulated in patients at the incipient stage of Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.12E-08 8.24E-04 4.38E-06 4.35E-05 53 165 "ACTN1,KIDINS220,APC,RGS20,ASPH,ATP2A2,ADGRB2,CLDN10,USP6,CDC27,DLGAP2,CLIP3,CSNK1G3,ARHGEF4,RIMS2,TENM1,DENND4A,FHL1,SEC23B,CAMKK2,GABRB3,B4GALNT1,TOX3,GLUL,GNAS,GPR22,HSP90AA1,DIPK1A,KIF5C,NELL1,OPA1,PAK3,FSD1,PPP3CA,RGS4,ROBO1,RPE,RPL38,KCNIP1,SCN3A,SEC31A,ELMO2,FAIM2,KIF1B,DDN,SST,NSFL1C,VAMP1,TAC1,ZMAT3,TMOD1,TRO,TTC3" Coexpression 20220088-SuppTable1 Human Immune_Allen10_2900genes GeneSigDB 7.53E-08 8.71E-04 4.61E-06 4.58E-05 359 1798 "RALGAPA1,ACADM,NCKAP5,FMNL2,BRAP,ESYT2,OSBPL1A,OSBPL6,ALCAM,BBOX1,GPRASP2,MRTFA,OGT,ANK3,KCNAB2,CACHD1,APP,SHTN1,CDC14B,SFMBT2,CASK,ARHGAP5,MARCH3,ZSCAN18,DACT3,CCAR2,ALDH4A1,EIF4G3,ATP2B1,N4BP2L1,ATP6V0A1,CFLAR,BMP7,DST,C1QC,NIPA1,FOXK1,CA12,DDR1,PTBP2,SLC25A14,HIP1R,RUNX1T1,ARHGEF2,CDC42,L3MBTL4,MAGI1,RCBTB2,FOXN3,RAB28,ZFYVE9,NMT2,CLTB,TJP2,TMEM184B,CNN3,FAM149A,ANKRD35,AKAP5,SLC4A8,ACBD5,ZFP28,C2CD2,SNCAIP,LRIG1,FEZ2,OSBPL3,PDE4DIP,PITPNM3,ARHGEF4,PUM1,ST18,USP6NL,FAM131B,CYBB,HDAC9,MYADM,ARHGAP32,TCAF1,RIPOR2,ARHGAP24,HDAC4,RIMS3,PHYHIP,DGKG,DCT,ZEB2,MYEF2,CNIH3,MFAP3L,GSDME,DLG2,DLG3,RPS6KL1,DPP6,DPYSL2,DTNA,SNX29,TSPAN5,EDN3,ATL1,ANKRD46,HIPK3,FEM1B,SEMA3D,SIDT2,OPTN,SH3GLB1,EFNB3,EBI3,EGFR,KMT5B,ABI2,AASS,KCTD3,EML1,ENO2,EPB41,EPS8,ERBB2,EFS,CDHR1,RCSD1,SIRPB1,KATNAL1,FAM198B,FABP7,TBC1D16,FCGR1A,ST3GAL6,FER,FGFR3,BAIAP2,FGR,CAMSAP1,MEX3B,PCYOX1,ATP13A4,FLT1,TACC2,SPECC1,STAMBP,DOT1L,MPP6,OGA,FYN,DKK3,GAB1,GABBR1,CHL1,AHCYL1,NEK6,NCKAP1,IQGAP2,ERAP1,TMEM8B,WASF3,GGTA1P,PPARGC1A,GLUL,KIAA1958,RAB40B,GNAL,LOXL3,GNAO1,LILRA1,LILRA2,RAPGEF4,TPPP,RFFL,NR3C1,GRM7,GUCY1A1,GUCY1B1,IRAK3,PADI2,ZHX1,HLF,SYNPO,HMGCR,AGFG1,IRF8,LRRC25,LRRCC1,IBA57,TUBB2B,ITGAM,ITGAV,CDH20,KCND3,KIT,STMN1,SMAD1,PIK3AP1,GPR155,MAN2A2,MAP2,MAP4,MBNL1,MEF2C,MEIS1,PPM1L,AFF1,SESN3,LAYN,MYO6,NBL1,NEFM,NEK1,NFIA,NFIX,NOVA1,NPTX2,NRCAM,OCRL,P2RY1,PBX1,PCMT1,PDPK1,PFKP,SSH1,A2ML1,CCSER2,ZFYVE21,PKM,KCTD15,GPSM2,PLTP,PSAT1,EPB41L4B,SH3KBP1,PPP2R2C,PPP3CB,PRKAR1B,PRKCB,GRAMD1C,SLC22A23,PTCH1,PTPRE,FAM120C,PTPRZ1,PTX3,SUSD4,ROGDI,RASGRF1,RDX,ZYG11B,MORC4,GTDC1,SEC61A2,PBRM1,RNH1,MYH14,CYB561D1,ROBO1,CCDC25,ATP8B4,RPS6KA2,LGR4,WLS,RTKN,ZNF568,TMEM156,AP1AR,SEMA6D,ATXN1,TNFRSF19,ASRGL1,KIF27,FERMT1,ASAP3,WDR47,SLC6A8,SLC6A9,YPEL4,SEPHS1,RAB3GAP1,SCMH1,MTERF2,GKAP1,SMARCA4,LIMCH1,KIF13A,PALLD,TMCC1,FAM126B,EMC1,SPP1,TEX2,ERC1,UNC5B,IQSEC2,SPART,PBLD,COLGALT2,SAMSN1,SOX21-AS1,MPRIP,ELOVL4,SEPT8,KANK1,KLHL7,SYNE2,KAZN,DDHD2,DNMBP,CAMSAP2,WWC1,TBL1X,ATMIN,TCF7L2,ZEB1,TCF12,DOCK9,OBSL1,NSD1,GPRIN3,SIK3,VWCE,ZMAT3,TGFBR3,AKTIP,SLC44A1,FBXL16,TIAM1,TJP1,TLR4,PARD3,TNNT1,LILRA4,TPM2,TRIO,RUSC1,SSBP2,TUBB2A,USP1,VSNL1,CLIP2,LAT2,CLDND1,RICTOR,ZNF711,NDRG4,SPIRE1,UPF3A,PMEPA1,STOX2,CIAPIN1,NAV2,ITM2C,TRIM16L,WIPF2,EPM2A,NLRP3,VANGL2,SSPN,FRMD6,DPF3,GAN" Coexpression 18006812-TableS4 Human Lymphoma_Piccaluga07_89genes GeneSigDB 7.89E-08 9.13E-04 4.80E-06 4.77E-05 29 68 "SERPINA3,ACHE,C1QTNF1,IGDCC4,CADM3,C2CD2,SNCAIP,PLCXD3,SNAP91,DNM1,ATN1,ARRDC4,EDN1,EDNRB,TUBB4A,OLFM1,FGF11,FOXF2,ABLIM2,GATM,LIFR,MT3,NFIA,SOX8,EFHD1,MCF2L,TNS2,DAAM2,TNS1" Coexpression 19658189-TableS8d Human EmbryonicStemCell_Xu09_85genes GeneSigDB 8.00E-08 9.25E-04 4.84E-06 4.81E-05 33 83 "KCNT1,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,ATP2B1,ATP6V1G2,HCN2,CACNA1G,CACNB2,HEPH,ABCC9,ATP5PD,KCNA4,KCNB1,KCNH2,KCNJ4,KCNJ5,KCNJ10,KCNJ11,HCN1,KCNIP2,SCN2B,SCN4B,SLC6A8,SLC8A1,SLC8A3,ABCC8,TRPC1,TRPC3,SLC30A3,KCNAB1" Coexpression 15558013-FigureS1b Human HeadandNeck_O?Donnell05_93genes GeneSigDB 8.91E-08 1.03E-03 5.37E-06 5.33E-05 30 72 "ADCY8,PTCH2,N4BP2L1,KSR1,ARHGEF7,CACNB4,ARHGAP33,ERBB4,CORO2B,FGF1,GABRB3,DENND2A,RAPGEF1,NXPH3,KLF12,KCNJ5,BCO1,MYO7A,NNAT,PKD1,PMP2,CNNM2,SHANK2,SOX10,THSD1,PCDHB6,TLL2,PIK3R5,SEZ6L,ZMYND8" Coexpression M2121 Genes correlated with classical type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.66E-08 1.12E-03 5.79E-06 5.75E-05 52 162 "SEMA6A,ABCD2,ARNTL,SLC4A4,BLM,CALM1,CAMK2B,CDH2,ADGRG1,CREB5,RGS6,OSBPL3,SIPA1L1,RASGRP1,EGFR,ERCC2,PIPOX,DLC1,FGFR3,DENND2A,GLI2,GNAS,GRIK1,GRIK5,ITGA7,KCNF1,LMO2,MEIS1,NDP,PCSK5,PMP22,ELOVL2,ACSS3,RFX2,RGS12,ZFHX4,KLHDC8A,ZNF671,SEMA6D,SLC6A9,SLC6A11,SLC12A4,NPAS3,ACSBG1,MLC1,KLHL4,WSCD1,NR2E1,HSPBP1,CLIP2,ZNF45,FZD3" Coexpression 18614019-TableS4a Mouse StemCell_Fazzio08_722genes GeneSigDB 9.78E-08 1.13E-03 5.83E-06 5.79E-05 124 509 "ASIC2,MTUS1,OSBPL1A,WDR35,AMPD3,OGT,PPFIA4,APOC1,CDC14B,MIER1,IGDCC4,ADGRB1,CFLAR,SYNJ2,SCAPER,DIRAS1,KALRN,PTBP2,ARHGEF25,CBFA2T2,CDC42,MAP4K4,ARMC8,SLC4A7,SMARCAL1,CLIP3,ATRNL1,GALNT9,CHD5,VCAN,CALY,ERC2,GPRASP1,SPOCK2,DNAJC6,DDX46,SACS,SRGAP3,TMCC2,KBTBD11,DMD,DTNA,HIPK3,LPAR6,ING4,DCTN4,ENO2,VPS13B,EFS,ZMYND10,FGF1,IP6K2,SYNCRIP,CGREF1,PNMA2,FUT9,GABBR1,TRAF3IP2,DCLK2,GNG3,PSRC1,B4GALNT4,GRB10,NR3C1,PSIP1,HAS2,PADI2,FRMD5,HSD17B1,CELF5,KNDC1,ARHGAP12,MATK,MDM4,MID1,FXYD6,NCAM1,NEUROD1,NME4,KCTD15,PLXNB1,PPP2R5C,EPDR1,PTCH1,PPP2R3C,RAB3IL1,SLC6A15,RGS3,RLBP1,SLC25A36,UEVLD,RTKN,FNIP1,CHD9,ST8SIA1,SLC1A3,SEPHS1,TRIM67,SLC15A2,IFT122,KIF13A,KIF21B,IZUMO4,LHFPL4,FCHO1,ADHFE1,PJA1,MCF2L,DNMBP,OBSL1,AKTIP,ARL10,TMPO,TPM1,TPM4,TRO,TTPA,VLDLR,MICU3,MAP3K12,SLC38A1,PCBP4,MVB12B,RNF170" Coexpression 18794137-SuppTable1b Human Breast_Creighton08_623genes GeneSigDB 9.91E-08 1.15E-03 5.88E-06 5.84E-05 102 398 "ABHD6,NME5,CC2D2A,SPOP,KIF6,API5,SHROOM2,CCDC74A,RNF182,ZNF599,CDK5R1,CASTOR3,JAZF1,CAMK2G,SLC25A14,LRWD1,LHX2,CLTC,NGEF,HECTD1,IQCK,FAM149A,SLC4A8,TOGARAM2,ARHGEF4,GAPVD1,DNAL1,SRGAP3,WDPCP,FSD1L,EML1,LRRC23,RAB9B,CDKL3,DNAJC27,CEP78,ZMYND10,CAMSAP1,SCARA3,IQCG,DCTN2,EFCAB2,POMT1,AK8,ABLIM2,KIAA1841,MSL3,GPM6B,KIF3A,FAM19A2,LINGO1,PSIP1,HSP90AA1,MAP6,EFHB,WDR49,DDX25,NPTX2,ODF2,SPATA6,CEP41,LRRC49,UHRF1BP1,TMEM231,CCDC40,REV3L,RFX2,RFX3,SEC61A2,NEK11,RMI1,HES6,PPM1E,DZIP1,RADIL,SHANK2,IFT122,TMCC1,ZHX3,CLUAP1,ENKUR,STOX1,NEK4,TCF7,RPGRIP1L,AKNA,DNAH7,TMEM121,NACC2,ACTR6,CDK20,ZNF346,PPIL6,TUB,FAM181B,CFAP52,REEP1,EML6,DNALI1,MDH1B,ST7,NETO2" Coexpression M2535 The '3/3 signature': genes consistently down-regulated in all three pools of normal mammary stem cells (defined by their ability to retain the dye PKH26). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-07 1.20E-03 6.10E-06 6.06E-05 48 145 "AK2,APP,IGDCC4,CA12,CALM1,ARHGEF2,CHN1,CNOT8,SLC24A2,ARMC8,BTF3L4,VCAN,GPRASP1,ARHGAP32,FGFR1OP2,DNM1,EBF1,RGS17,STX2,FHL1,GABBR1,WASF3,TNRC6A,GUCY1B1,KLF12,JAK1,KITLG,ZNF862,NASP,GNG2,PCDH18,FAT3,TUG1,ACER3,NCBP3,CHD9,TROVE2,EPB41L3,TCF7L2,PCDHB10,PUM2,HEY1,TPM4,TRIO,TRPC1,RUSC1,JMJD1C,RNF146" Coexpression 18667080-TableS8 Human StemCell_Kocer08_236genes GeneSigDB 1.06E-07 1.22E-03 6.20E-06 6.15E-05 62 207 "LGR5,DDX3Y,BARD1,SYNJ1,ARHGEF2,CDH10,MAGI1,CDO1,LHX2,EPS15L1,SLC24A2,COL9A2,TCEAL2,AKAP12,CRYM,VCAN,HDAC9,TOX,DCT,ZEB2,HEPH,DPYSL2,EDNRA,EDNRB,RASGRP1,PLXNC1,ATP8A1,FOXF2,FYN,MALT1,GLDC,GPM6B,STON1,GRB10,GSTM5,WIF1,HBA1,HSP90AA1,CD200,FXYD6,NASP,NOVA1,OPHN1,PCSK2,PDE3B,ENPP2,SERPINE2,PPP2R5C,RIPOR1,FBXW7,RPS20,ARHGEF40,SHANK2,PDZRN3,ZCCHC24,KDM4C,ACSBG1,VAMP1,SYN2,TRO,TRPS1,TTC3" Coexpression M7666 Genes up-regulated in ex vivo follicular dendritic cells: peripheral lymph node versus Peyers patch. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-07 1.24E-03 6.24E-06 6.19E-05 60 198 "SERPINA3,OGT,AQP4,ASGR1,ADGRB3,CANX,CAPN3,TMEM257,SEC31B,AATK,FAM131B,DCAF8,HDAC4,TOMM20,SV2B,DOCK2,SUGP2,MBNL2,ELAVL3,EZH1,SH3YL1,ZMYND10,FGF13,CAP2,TRIM16,SARAF,DOT1L,SEPT9,GFRA2,LUZP2,HSPA1L,IL11RA,ADAM22,NOVA1,PIK3C2A,PLCD1,PLP1,PPP3CA,PRKAB2,PRODH,MEG3,SEC31A,SLC1A6,PALLD,ZHX3,PEG10,ZC3H4,DDHD2,TAL1,SYNE1,TEK,NACC2,TPM3,TSN,TTC3,CADM1,NSD2,INTS3,MPPE1,CAMK1G" Coexpression 17312329-SuppTable2 Human Leukemia_Juric07_617genes GeneSigDB 1.11E-07 1.28E-03 6.43E-06 6.39E-05 112 449 "CPNE2,ADCY6,ADD2,SEMA6A,SPOP,AMH,ANK1,DACT3,RIPK1,BMPR1B,CASTOR3,JAZF1,CAST,ADGRG1,FOXN3,CHN2,JAM2,NRXN3,TJP2,CNN3,TENM4,MICAL2,OSBPL3,VCAN,CTNND1,RIPOR2,ARHGAP24,TOX,ZEB2,DNM2,RASGRP1,EPB41,DMTN,EPS8,NRN1,FECH,TMEM164,PDLIM5,PRELID3A,TPPP3,FYN,GAB1,HBS1L,JPH4,GRM5,ADAMTS6,IRAK3,RASSF8,HBA1,TOX2,KLF12,ICA1,RBPJ,TTYH2,CD200,NEXMIF,MYT1,NF1,NFIA,NFIX,NTRK3,NUCB2,PBX1,PDE1B,DUSP26,PKM,SCHIP1,IRX1,PPP2R5C,GRAMD1C,SYTL2,PTPRB,PRIMA1,SETD5,KLHDC8A,FBXW7,BAALC,PRR5L,RTN1,ZNF331,SOX6,SLC2A5,BTBD3,SLC6A8,SLC14A1,LIMCH1,SNCA,ITPRID2,CEP68,SYT11,PRRC2C,ANKRD28,ATP11A,ROBO3,ACSL6,ZEB1,PSD3,SIK3,SLC44A1,TNFRSF1B,CSMD1,TNS1,TRIO,TRPS1,DCBLD1,CADM1,OSBP2,NPDC1,ZNF184,SLC38A1,CAB39L,RGS7BP" Coexpression M16496 Top 200 marker genes up-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-07 1.33E-03 6.66E-06 6.62E-05 55 176 "ABHD6,ACTN2,AXIN2,ADRB2,SPARCL1,GPAM,LGR5,AQP6,CDC14B,SLC4A4,SLC16A4,ABCG2,MYRIP,FAM169A,RHOBTB1,DYNC1I1,ECM2,TSPAN5,GPHN,FGF13,CAP2,PHYHIPL,ALDH1L1,GFRA1,GLUL,FRMD3,HLF,NKD1,ZNF385B,KCNK1,AQP11,SEPT4,CRLS1,FITM2,PLPPR1,PTPRG,ACSS3,TMEM100,PRR5L,SALL1,HOGA1,TNFRSF19,NUBPL,SLC1A2,SLC22A4,ANKFN1,ACSL6,THBS4,RUNDC3B,AMACR,TTPA,HEPACAM,DNAJC12,VLDLR,SLC13A3" Coexpression M1962 Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.19E-07 1.38E-03 6.84E-06 6.79E-05 20 38 "CNTNAP1,NOL4,CALY,SACS,EXTL1,MCHR1,LRRTM3,KCNA4,MEIS1,OPCML,PCSK1,SERPINI1,ROBO2,TMEM100,SOX6,YPEL4,SYT1,PCDH20,MDH1B,PAK5" Coexpression M2395 Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.21E-07 1.40E-03 6.91E-06 6.86E-05 52 163 "NDRG2,ADCYAP1R1,SPARCL1,C1QC,DCLK1,CNR1,ZNF521,AKAP12,CSF1,NRSN1,SV2B,NTM,DNM1,EGR3,ELAVL2,EPB41L2,EPHA5,FABP7,EFEMP1,FGF13,FGF14,SCARA3,NSG2,DKK3,GAB1,CHL1,GAP43,CPLX1,STMN2,GRM7,GUCY1A1,ACOT7,ITGA7,KCND2,MAP4,MEIS2,HCN1,DUSP26,SERPINE2,PMP22,SEPT4,PTN,PTPRO,SLC6A15,RNASE1,ZFHX4,SNCA,SOX2,UCHL1,MICAL1,FSTL5,PCDH15" Coexpression M2806 Genes up-regulated in astrocytes. MSigDB C6: Oncogenic Signatures (v6.0) 1.23E-07 1.42E-03 7.00E-06 6.95E-05 37 100 "ADCYAP1R1,AGT,ABCD2,GPAM,APP,RGS20,ATP1A1,BMPR1B,CBS,HAPLN1,HEPH,CHRDL1,FGFR3,ATP13A4,GABRG1,AIFM3,GRIN2C,FRMD5,BTBD17,KCNJ16,SCG3,PAK3,GPR85,PHKG1,PPARA,ELOVL2,RORB,TNFRSF19,SLC30A10,SLC1A2,SLC6A11,COLGALT2,HEY2,NTSR2,TTPA,LGI4,SPIRE1" Coexpression M8451 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.27E-07 1.47E-03 7.19E-06 7.14E-05 122 501 "XKR4,FMNL2,ESYT2,TAOK1,SRPX,CASK,ARHGAP5,ARHGDIA,ASPH,STX16,ATP2B1,BACH1,DST,CALB1,CAMK2D,CDC27,TPP1,AHCTF1,CREM,HAPLN1,MICAL2,DOCK4,HDAC9,TM9SF4,ZC3H11A,SMG7,G3BP2,CPEB2,E2F5,EDIL3,ANKRD46,APH1A,MBNL2,EIF4G1,GPHN,FAM198B,WAC,SH3YL1,OLFM1,USP16,KHDRBS3,OGA,GALC,IQGAP2,ARFIP1,GFER,GLYR1,GLS,STMN2,GRB10,IL1RAPL1,GUCY1A2,HAS2,UBE2QL1,MIER3,HNMT,IFI16,IL6ST,JAK1,KCNMA1,MAP2,MBNL1,KITLG,MMP16,ZNF92,MYO6,NF1,NFYA,OGDH,PDE4B,GNG2,SERPINE2,PMP22,MAPKAP1,FAT3,PPP3CA,PRKACB,PKIA,PTPRB,PTPRO,PTX3,PLEKHB2,RASGRF1,SLC6A15,GTDC1,RFX3,RGS4,SETD5,UEVLD,CNTNAP3,AP1AR,PPP4R3A,CCDC88A,SLC12A4,SLC14A1,CPEB4,TNIK,BDP1,SPP1,MIR100HG,ITPRID2,NXT2,STX1A,ADGRL3,FBXW11,PCDHB15,ZMAT3,HHIP,ENHO,TLR4,TRIO,DCBLD1,PLEKHH2,NDRG4,ZBTB38,SPIRE1,TUBA1A,NAV3,KAT6A,PHTF2,JMJD1C,FXR1" Coexpression M17923 "Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.29E-07 1.49E-03 7.25E-06 7.20E-05 107 425 "SERPINA3,ACLY,NDRG2,MTUS1,C1QTNF3,ALCAM,SRPX,LTBP4,ANK2,GAS7,APOC1,ASPA,ZBTB10,N4BP2L1,BCHE,IL33,RUNX1T1,CBS,CDH2,DCLK1,CDO1,CRLF1,COL4A5,ABI3BP,HAPLN1,MICAL2,GSDME,RHOBTB1,RABGAP1L,CHRDL1,DNM1,ECM2,EDNRB,FAM13A,EGFR,EIF5,TENM1,EIF1,RASL12,ATP8A1,FLNC,SORBS1,PDLIM5,ERAP1,GGT5,RND1,GLS,GSN,GUCY1A1,GUCY1B1,HLF,ELOVL5,SCRG1,SYNPO,IGF1,IL6R,KCNK2,MARK1,MATN2,LRP1B,MITF,ADAM22,MT1M,MX1,HNRNPM,NELL2,NINJ2,NOVA1,NTRK2,OXTR,PFKFB3,SERPINE2,PIK3R1,FXYD1,PLTP,PSAT1,SPATA6,ELOVL2,PTPRD,PTPRO,RAP1GDS1,RGS4,TMEM100,ATP8B4,RPS6KA2,SCG5,SHMT2,ANKRD36,LIMCH1,DOK5,EMC1,LMO3,POPDC3,TGFBR3,NACC2,TIMP4,TMPO,TP53BP2,TPM2,TPM4,UCHL1,ZBTB16,SYNC,SLC38A1,KCNAB1,ADAMTSL3,SSPN" Coexpression M2520 Loci bound exclusively by SALL4 [GeneID=57167] isoform b in ES cells (embryonic stem). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.36E-07 1.57E-03 7.63E-06 7.58E-05 125 517 "CDC7,MTUS1,SPARCL1,DPP10,MAP4K3,CASK,ASPA,PTCH2,ADAM23,BARD1,DST,CACNA2D1,MAP7,INA,CD38,DIS3L,CNOT8,CLCN3,ABCG2,PCYT1B,RCHY1,NCOR1,VCAN,SOCS5,PNPLA8,NRSN1,KIAA0408,HDAC9,TM9SF4,IST1,ELMO1,RUSC2,SRGAP3,FAM107B,CPEB2,RCAN1,DNAJB6,FEM1B,DMTN,PIPOX,RTN3,TUBB3,UBE2E3,EFCAB2,UFM1,NPTN,FUT9,GAD1,GAD2,SALL3,GAP43,DBF4,SPIN1,CBX1,ADAP1,GPR19,LPAR4,PCLO,ADAMTS6,PACSIN2,HLF,ATCAY,RBPJ,LRRCC1,TUBB2B,LRRTM3,KLHL23,KIT,IPO5,ARHGAP12,EFHB,MEIS1,MGAT3,NDUFA5,NEUROD1,NFE2L2,NODAL,PAX6,GDAP1L1,ANLN,PRIMPOL,DRAM2,PPP3CC,FAM120C,RFX4,SLC25A36,RIC8B,SETD5,RPS20,RTN1,CSRNP3,TNFRSF19,SFPQ,ASRGL1,ST8SIA1,ANKRD6,EPN2,SLC6A1,CCDC88A,INAVA,KIF13A,SPP1,LMO3,PBLD,TROVE2,TCEA1,SLC19A3,OBSL1,ITGB3BP,LEFTY2,TIMP4,CBX5,PARD3,RBFOX2,TRH,PORCN,ZFP37,ZIC3,ZNF708,ZNF189,UPF3A,WNK1,RTN4,PHTF2,RNF146" Coexpression 18794137-SuppTable1a Human Breast_Creighton08_772genes GeneSigDB 1.40E-07 1.62E-03 7.84E-06 7.78E-05 123 507 "ABAT,NCKAP5,KIAA1324,OSBPL6,SEMA6A,GPRASP2,OGT,APBB2,ZBTB10,BARD1,BCS1L,DST,RAB29,WASF1,CA12,ARHGEF2,CDC25B,LARGE1,EPS15L1,FAM189A2,HOMER3,COL4A5,FEZ1,ATRNL1,GREB1,RIMS2,DCAF4,TCAF1,ARHGAP24,PHF19,TBC1D5,DLG2,DSCAM,DTNA,MAMLD1,FARSB,SEMA3D,ABI2,EGR3,ERBB4,ARMCX1,DLC1,PRMT5,OLFM1,TMEM164,FHL1,CAP2,EVL,ZBED3,GFRA1,SPIN1,RAB30,GPER1,NUDT21,GRIA2,ARHGAP36,IGSF1,ZNF385B,JAK1,IPO5,L1CAM,LAMP2,SYTL4,MAP4,MAPT,LDLRAD3,MEST,THYN1,MYO5A,NAP1L2,NRCAM,PBX1,SNX10,KCTD15,FTO,PMP22,TNPO2,PPP2R5E,SYTL2,ELOVL2,PTPRG,ACSS3,RBBP8,VEPH1,ELP2,CCDC112,SARS,ATXN1,SHMT2,SYBU,EFHD1,ZFP1,PALLD,SOX3,ZCCHC24,ERC1,CEP68,NECAB1,PLCB1,SYT1,ANKRD28,MMS19,CAMTA1,TBL1X,TIAM1,HEY2,TNNT1,TPM3,SYNPO2,METTL3,SGK3,CADM1,DNAJC12,VGF,ZIC2,ZNF711,LYPD6,DHX33,SLC38A1,SEMA3B,FZD3,DOCK8,FRMD6" Coexpression 18381933-SuppTableS4 Human Breast_Vincent-Salomon08_1001genes GeneSigDB 1.48E-07 1.72E-03 8.23E-06 8.18E-05 175 781 "RALGAPA1,SERPINA3,ABAT,RBM10,ADCY6,BRAP,OSBPL1A,KIAA1324,PLA2G6,AMT,PKP4,APBB2,FAM131A,MADD,ARHGAP5,MARK4,CHRD,ATP1B3,STX16,N4BP2L1,ADAM15,BMPR1B,CA12,SLC16A4,SCARB1,LRBA,ARHGAP33,MAGI1,CACNA2D2,SRSF11,CHN1,PLEKHB1,MYL6B,FADS2,MAP4K4,WHRN,LETMD1,SH2B1,NCOR2,ABCG1,SOCS5,CST3,KIAA0040,GREB1,PPP6R2,NOS1AP,DCAF8,DAPK1,ARMCX2,FBXL5,NR1D2,DOCK2,ATN1,EEF1A2,FEM1B,FRY,SIDT2,RASA4,KCTD3,SORBS3,COPS4,TNK2,DCTN4,GPHN,ERBB2,ERBB4,EZH1,F8,ARMCX1,FCGRT,KIAA1109,FGFR1,CAMSAP1,CAP2,SYNCRIP,EVL,SORBS1,PDLIM5,ARFGAP2,STAG2,ZNF44,AHCYL1,SYT17,BRD8,GLYR1,MSL3,GLUL,NUDT21,PADI2,ARHGAP19,HMGCL,AGFG1,IRF8,IL6ST,KCND3,KIF5C,LIMS1,MAN2A2,MAOB,MAPT,MATN2,PTOV1,NF1,NOVA1,NTRK2,NUCB2,NUMA1,OXTR,PBX1,SERPINI1,MAPKAP1,RETREG2,FA2H,MINDY2,PKN2,PTHLH,ELOVL2,PTN,PTPN13,PEX5,SUSD4,RBBP8,BSDC1,RET,TTLL7,ROBO1,PCMTD2,ZC3H14,STK32B,AP1AR,SH3BGR,SYBU,CDK5RAP3,SMARCA4,SMARCC2,SMARCD3,INTS9,LMBRD1,KDM4B,SOX10,SOX11,CLUAP1,GLT8D1,DBNDD2,SPTAN1,CLSTN2,POGZ,KANK1,ANKRD28,DDHD2,MLST8,DNMBP,TBL1X,WASHC4,SIK3,ZNF106,TPM4,TRPS1,SGK3,CADM1,UBE3A,DNAJC12,LMF1,WRN,UPF3A,PMEPA1,MAP3K12,DNALI1,PARP6,LMAN2L,SEMA3B,NAV3,NAV2,FZD3,FXR1" Coexpression 20386565-TableS1 Human Prostate_Zhao10_1841genes GeneSigDB 1.49E-07 1.72E-03 8.23E-06 8.18E-05 146 627 "ADAR,ADD1,SEMA6A,AMPD2,ANK3,APBB1,BCAS1,ARRB2,DYNLL1,ATM,ATP1B3,ATP2B1,N4BP2L1,BACH1,CA12,SPAG9,KRIT1,CCNT1,CDC42,LRRFIP1,TPP1,CLTB,FBXO7,NIPBL,SLC4A7,COX4I1,CREM,ENTPD4,FEZ2,VCAN,CST3,GREB1,TOMM20,COPS7A,POM121,DTNA,ABCC5,EDNRA,HIPK3,EFNA2,SUGP2,EIF4G1,SORBS3,ELN,EPS8,ERBB2,EZH1,TUBA1B,PTK2B,ATP8A1,CHST15,FGFR1,FHL1,VTI1B,FLNC,PDLIM5,KHDRBS3,CELF1,FYN,GAA,AHCYL1,ZMYND11,IQGAP2,MTHFD2,TUBGCP4,AHDC1,BRD8,STARD3,CBX1,OS9,GP1BB,PCLO,DIDO1,CLASRP,HBA1,ATXN2L,GABARAPL2,HP,HSP90AA1,MSL1,IL6R,IL6ST,ITGAV,SMAD1,MAOB,MAPT,MATN2,MIA2,MSI1,NEFH,PBX1,PCMT1,SSH1,PIK3R1,MBOAT7,POLG,MED1,PPM1B,PRKAB2,PKN2,PTCH1,PTN,PTPRN2,RBBP8,RDX,RNASE1,SEC14L1,SUPT20H,FAM102A,CLSTN1,SLC6A7,RAB3GAP1,SLC20A2,TMCC1,KIF21B,KDM3A,SPP1,SRPK2,CEP68,PHLDB1,ZC3H4,ANKRD12,CAMSAP2,WWC1,FBXW11,TBL1X,TCF12,SIK3,TNNT1,TP53BP1,TPM1,TPM2,TRIO,RUNDC3B,ZMYND8,RUSC1,HIRA,UBE3A,VGF,XPO1,REEP1,WNK1,URM1,MPPE1,ST7,RTN4" Coexpression M9778 Genes up-regulated in resting CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.58E-07 1.83E-03 8.57E-06 8.51E-05 60 200 "ABCD2,ZNF687,ARRB1,MARCH3,ATP1A1,MYOM1,PROM1,CBR1,SYNGR3,MS4A7,TPP1,MAGED1,C2CD2,ABCG1,AATK,TENM4,CHD5,SDC3,KIAA0513,RIMS3,DBI,SIRPA,ABCC5,SEZ6L2,OPTN,ADGRV1,FCGRT,ACTL6B,DOT1L,GAB1,ALDH1L1,GLI2,GPD1,SYNPO,KCNJ9,MAG,KCTD6,SCAMP5,MYO7A,NDUFA5,SETD4,OCRL,CAMKV,PILRA,KIF7,RXRA,MRAS,SH3BP2,ITSN1,SLC1A3,MAPKBP1,GLT8D1,KIF1B,FAM168A,SYNE2,ATP13A2,TF,PRRT1,RFTN2,NHSL1" Coexpression M7762 Genes down-regulated in macrophages: wildtype versus MYD88 [GeneID=4615] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.58E-07 1.83E-03 8.57E-06 8.51E-05 60 200 "SPARCL1,ARHGAP20,ANK1,TNRC6C,MTMR3,LDB2,NEURL1,MYOM2,AKAP12,AATK,SNCAIP,LRRC3B,ACY3,SCRN1,CHRDL1,CDON,DTNA,EYA1,HSPA12B,NRN1,ST3GAL6,SCARA3,FLNC,GALNT15,ARPP21,GPD2,GSN,COQ10A,BVES,GUCY1B1,ARHGAP19,VSIG4,SLC35G1,KCNH2,KIT,MEST,CD200,MYL3,FXYD6,NPR2,PDE2A,EPB41L4B,PCMTD2,ARMH4,SEMA6D,PRCD,SMTN,LIMS2,SCN3B,NMNAT2,ADHFE1,KANK1,TF,ZFP91,ERCC6L2,CA14,CCDC136,LYPD6,PROCA1,HRASLS" Coexpression M7495 Genes down-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]. MSigDB C7: Immunologic Signatures (v6.0) 1.58E-07 1.83E-03 8.57E-06 8.51E-05 60 200 "NDRG3,HACE1,EPB41L5,GPAM,MADD,MARCH3,MYOM1,ST3GAL5,CLDN10,CBFA2T2,CD38,FADS2,CSNK1G3,PITPNC1,E2F6,EPB41,HSPA12B,ATP8A1,MED12L,FHL1,FOXO3,NBEA,GAB1,RAB40B,IL1RAPL1,HLF,CELF5,LRRCC1,MAN2A2,PPM1L,AFDN,SESN3,MYCN,NAP1L3,SFR1,NFIA,PFKFB2,MINDY2,GRAMD1C,FAM120C,FAM184A,TRIM68,GTDC1,MEG3,PEAR1,SOX6,ITSN1,CCDC88A,TNIK,C3orf70,EHBP1,PSD3,SIK3,TGFBR3,TJP1,TSC1,CCDC136,PLSCR4,ST7,KLHDC1" Coexpression M8082 Genes up-regulated in myeloid-derived suppressor cells with HDC [GeneID=3067] knockout: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 1.58E-07 1.83E-03 8.57E-06 8.51E-05 60 200 "SLITRK1,PLA2G6,UNC79,LRCH2,DDO,SFMBT2,CA8,CDH10,SLIT2,SLC24A2,HAPLN1,SEC14L5,PYGO1,NTM,SLC29A4,SEZ6L2,FGF14,SUCO,FAM49B,RAPGEF6,ARPP21,GPR162,ADAM28,GLRB,GRIA2,FRMD5,HSF2,HTR5A,KCNC2,KCND2,GPR62,LAMP2,MTTP,CNTN3,PCDH8,GPSM2,TRHDE,SEPT4,FAT3,DRAM2,LRRN3,PRKCG,PLPPR1,NUDT11,NEK11,BAALC,HOGA1,SH3GL3,NLGN1,SOX1,C11orf87,SYP,VWC2,ZFPM2,CSMD1,RICTOR,MKRN3,FSTL5,PCDH15,VANGL2" Coexpression M10961 Genes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [GeneID=2099]) compared to the parental MCF7 cells which do. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.59E-07 1.83E-03 8.57E-06 8.51E-05 173 771 "SERPINA3,ABAT,NCKAP5,KIAA1324,ALCAM,PCDH10,ANK3,APBB2,EPB41L5,DGKD,BCAS1,SHROOM2,CASK,ZNF583,MPDZ,BMPR1B,RAB29,CA12,CACNB4,DCLK1,LARGE1,CCPG1,ADGRG1,PLEKHB1,SLIT2,EPS15L1,CLU,FAM189A2,COL4A5,ANKRD35,AKAP5,MAGED1,HS3ST5,CP,NSL1,ATRNL1,FAM169A,GREB1,CTNND2,CCDC144A,HDAC9,KIAA0513,SCRN1,ARMCX2,YTHDC1,LYPD1,SGSM2,CPEB2,SLC12A6,DSCAM,DTNA,EDN1,EEF1A2,RASGRP1,TMTC1,EGR3,LPAR6,EPB41L1,ERBB4,FAM198B,EFEMP1,CHST15,OLFM1,FGF13,CAP2,EVL,NBEA,PDLIM5,TPK1,FUT9,GAD1,SALL3,NEK6,GFRA1,RAB40B,GPER1,GPR37,ATP2B1-AS1,GRIK3,GSN,GUCY1B1,UBE2QL1,ZDHHC15,LRRCC1,KCNJ3,KLHL23,MAP2,MATN3,KITLG,PPM1L,MITF,MMP16,SESN3,MX1,MYO5A,MYO6,NCAM2,NELL2,CNOT4,NRCAM,NUCB2,GPR137C,KCTD15,HMGCLL1,SDK2,PKIA,DIRAS2,MASP1,SAMD9,SYTL2,SIDT1,PTPN13,PTPRG,SUSD4,RBBP6,RET,FIGN,RNASE1,ELP2,RPS6KA2,MEG3,WLS,AMER2,SEC14L1,SELL,SGK1,FAM102A,PPM1E,SLC1A2,SLC6A8,SLC9A5,SHANK2,SLC12A2,COA1,IFT122,PDZRN3,SOX2,SOX3,NPAS3,SPART,DIP2A,KANK1,NECAB1,C3orf70,PLCB1,TMEM150C,SYT1,TCF4,TRIM2,PCDHB10,PCDHB7,PSD3,AHCYL2,BEX4,RBFOX2,SYNPO2,RUNDC3B,TRPS1,RPRM,DNAJC12,TOM1L2,VLDLR,PMEPA1,PRTFDC1,TUBA1A,CAB39L,DOCK8,CERS6,TIGD6,FRMD6,DPF3,CPNE4,SPATA13" Coexpression 11559565-Table3 Human Brain_Rickman01_53genes GeneSigDB 1.70E-07 1.96E-03 9.13E-06 9.07E-05 24 52 "RUNX1T1,COL9A1,COL9A3,VCAN,DTNA,EGR3,TNK2,GPR17,GRIA2,KLRC3,NCAM1,NTRK3,OPCML,OXTR,PDE4B,SERPINE2,PIK3R1,PRKACB,SGK1,SNCA,THBS4,TIMP4,TMOD1,ZBTB16" Coexpression 19185848-Table1 Mouse StemCell_Read09_41genes GeneSigDB 2.08E-07 2.41E-03 1.12E-05 1.11E-04 20 39 "SEMA6A,CDK5R1,FBXO7,ELAVL4,ACTL6B,AIFM3,KLF12,CELF5,SCRT2,L1CAM,NEUROD1,NHLH1,NRCAM,SH3KBP1,MAPK10,CPEB4,CNTN2,GPRIN3,ZFPM2,CELF4" Coexpression M9808 Genes down-regulated in at day 0 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO. MSigDB C7: Immunologic Signatures (v6.0) 2.13E-07 2.46E-03 1.13E-05 1.13E-04 59 197 "TKTL1,SEMA7A,KSR1,CD86,ARHGEF2,CACNA2D2,FBXO7,WHRN,CREM,CREB5,NCOR2,LRIG1,PITPNC1,SV2B,FAM107B,EBF1,PLXNC1,GTF2IRD2,DCTN2,RAPGEF6,C1QL1,GNG4,PRRC2B,NXPH3,SYNPO,USP54,TTYH2,MATN2,SRSF12,AMZ2P1,NEFH,PDE4B,PDE4D,TMOD2,SSH1,RETREG1,TNPO2,PCDHB17P,PKIA,TMEM145,RAB5B,RBBP6,ST6GALNAC6,KIF21A,SLC12A4,ATF7IP,KIF13A,GLT8D1,CEP68,ZC3H4,TAF6,TBL1X,TP53BP1,KCNE5,CLIP2,CLDND1,WNK1,MVB12B,FXR1" Coexpression 18504433-SuppTable1 Human Liver_Liao08_600genes GeneSigDB 2.20E-07 2.55E-03 1.16E-05 1.16E-04 129 542 "RBM10,CDC7,PKP4,DGKZ,CDK13,ASPH,EIF4G3,BARD1,MTMR2,CA12,ARHGEF1,CBFA2T2,ARHGEF2,NUMBL,CLTB,MAP4K4,COL11A2,FAM171B,SH2B1,CSNK1E,VCAN,CTNND2,PHF19,KIAA0513,DBN1,DNAJC6,MYEF2,B3GAT3,RHOBTB1,SLC29A4,DTNA,DUSP9,DNM1L,ANKRD46,EEF1A2,PLXNC1,ENO2,MFSD10,RACK1,GORAB,SYNCRIP,FOXM1,EFCAB2,ZCCHC17,ATP2C1,PHYHIPL,GABBR1,MTHFD2,SEPT9,GLS,TOX3,KIAA1958,MAP7D2,GNAS,GNG4,PRRC2B,RAPGEF1,SLC2A6,GYG1,PACSIN2,ATXN2L,ITGAV,KCNH2,KIF2A,MAP2,MAP4,MBNL1,SCAMP5,DDX25,NACA,NFIA,NRCAM,ZNF827,PCSK5,PDCD2,PFKFB4,OLA1,SERPINE2,PKM,SMOX,PTPA,MAPK3,VPS13C,PTK2,SUSD4,FIGN,TTLL7,SLC25A36,ZNF532,ROBO1,ROBO2,GLDN,HUNK,ASRGL1,PPP1R9A,FERMT1,HKDC1,FHOD3,SLC6A8,ARFGAP1,SMARCE1,SNAP25,TMCC1,EMC1,SRPK2,ZNF302,PLCB1,POPDC3,AGTPBP1,TCF12,PUM2,ATP13A2,CBX5,DDHD1,KCTD2,TPD52L2,TPM2,TRPC1,TRPS1,SSBP2,TUBB2A,UCHL1,MEAF6,NSD2,ZIC2,ZFP41,STOX2,NAV3,NETO2" Coexpression M3695 Genes up-regulated in prostate cancer samples bearing the fusion of TMPRSS2 with ERG [GeneID=7113;2078]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.20E-07 2.55E-03 1.16E-05 1.16E-04 28 67 "AMPD3,CADPS,NCOA1,EIF4G3,BMPR1B,CACNA1D,MAP7,COL9A2,SIPA1L1,DBN1,EIF5,SH3YL1,KHDRBS3,SEPT9,GHR,RAB30,GP1BB,KCNN2,KLC1,MYO6,CDK14,PRKAR1B,PSMD13,RGS10,SAFB,ABCC8,PCDHGB7,ZMYND8" Coexpression 20211691-TableS1 Mouse NeuronalCells_Provenzano10_158cells GeneSigDB 2.23E-07 2.58E-03 1.17E-05 1.16E-04 36 98 "ADCY8,ARRB1,BRINP2,RASL11B,CALB1,DCLK1,SEC24C,DBN1,DMD,DMPK,SCML2,GPR22,FRMD3,IGF1,KCNK1,KCNK2,SYTL4,GPR155,MT3,RSPO2,MYBPC1,NAP1L3,NELL2,NTRK3,DUSP26,PACSIN1,GDPD2,PTPRD,SUSD4,SEMA6D,FRMPD1,SLC1A2,SLC14A1,DOCK9,PRMT8,PAK5" Coexpression M5942 Genes down-regulated in response to ultraviolet (UV) radiation. MSigDB H: Hallmark Gene Sets (v6.0) 2.25E-07 2.60E-03 1.18E-05 1.17E-04 47 144 "ADD3,SPOP,AMPH,CDC42BPA,APBB2,CDK13,ATP2B1,SYNJ2,CACNA1A,KALRN,NIPBL,SIPA1L1,YTHDC1,MAGI2,NR1D2,CDON,DYRK1A,ERBB2,F3,EFEMP1,DLC1,CAP2,PDLIM5,ATP2C1,FYN,NR3C1,HAS2,ICA1,KCNMA1,KIT,MMP16,PIK3CD,PMP22,SCHIP1,RGS4,RXRA,ATXN1,SCN8A,SCAF8,WDR37,ARHGEF9,SYNE1,TGFBR3,TJP1,VAV2,VLDLR,PRDM2" Coexpression M5919 Genes up-regulated by activation of hedgehog signaling. MSigDB H: Hallmark Gene Sets (v6.0) 2.33E-07 2.69E-03 1.21E-05 1.20E-04 19 36 "ACHE,NRP2,CDK5R1,ADGRG1,CNTFR,CRMP1,DPYSL2,L1CAM,NF1,NRCAM,OPHN1,PTCH1,RTN1,SLIT1,HEY1,HEY2,AMOT,VLDLR,SCG2" Coexpression 17297478-SuppTable5 Human Intestine_Vecchi07_1024genes GeneSigDB 2.40E-07 2.78E-03 1.25E-05 1.24E-04 174 781 "ABAT,ADRB2,INTS2,NME5,KIAA1324,SRPX,AMPH,AQP4,ASPA,ATP1A2,BARD1,BCHE,BID,BMPR1B,FUBP1,VSTM2A,PRC1,CLDN10,INA,CDC25B,LONRF2,CFL2,CHGA,CHGB,JAM2,SLIT2,CLU,CNTN1,TCEAL2,MYRIP,MFSD4A,PLCXD3,ARHGAP24,CENPL,MATR3,RIMS3,ARMCX2,DNAJC6,MAGI2,CHRDL1,DMD,ARRDC4,DTNA,EBF1,SIDT2,RCAN2,LRRC17,KCNMB2,RAB9B,ARMCX1,ABCA8,EFEMP1,ST3GAL6,FHL1,FOXM1,NOP56,NELFCD,CSPG5,FUT9,GABBR1,GABRB3,GAD1,CPLX1,DNER,GCNT2,ADAM28,GHR,LYVE1,GLUL,MAP7D2,GNAO1,GPM6B,GPER1,EML4,NR3C1,FAM107A,WIF1,UBE2QL1,PTGDR2,HLF,HMGB1,IDH3B,IL6R,ZNF385B,KCNJ5,KCNJ16,KIF5C,KIT,LAMA2,LIFR,GPR155,SAMD5,COMMD5,MT1M,MTTP,NEXMIF,BEX5,NAP1L2,NASP,NCAM1,ALDH1L2,SMIM11A,NTRK3,PCDH9,ENPP2,PFKP,SERPINI1,ANLN,GPSM2,PLIN1,PLP1,SLC36A4,PRKACB,PROX1,KLK6,SPDL1,PTPRZ1,PID1,ATG16L1,SUSD4,BEND5,VEPH1,FIGN,RGS4,PRIMA1,TTLL7,GSTCD,TMEM100,SCN7A,IL17RB,SOX6,SH3GL2,FERMT1,SLC1A2,SLC6A8,SMARCA4,SMARCE1,SNRPN,SOX2,SPP1,BEX1,SPTAN1,SPART,ATP10B,PBLD,SST,SSTR1,ERBIN,SYT4,ATP11A,SEMA4A,MCF2L,UNC5D,ADGRL3,TPCN2,HHIP,TPM1,RGMB,SYNPO2,TRIO,PDSS1,TMEFF2,PITPNB,VLDLR,NSD2,CLDND1,ETNPPL,XRCC4,PCDH20,ZIC2,ZFP41,PMEPA1,LRP8,STOX2" Coexpression 12446012-Table3 Mouse Immune_Carmody02_40genes GeneSigDB 2.51E-07 2.90E-03 1.30E-05 1.29E-04 18 33 "HCN2,CACNA1G,CACNA1A,SLC25A14,SIRPA,SNAP91,ELAVL2,FABP7,CHL1,GFAP,GFRA2,GUCY1B1,OPRL1,SCN8A,BCAN,SNAP25,VAMP1,SYT1" Coexpression M8400 Genes down-regulated in brain microglia versus spleen CD8- dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.58E-07 2.98E-03 1.33E-05 1.32E-04 59 198 "ASIC2,ACHE,ADD2,AP2A2,ABCD2,PPFIA3,CDC14B,PLA2G4C,ATM,ADGRB1,CACNG1,RCBTB2,SLC22A6,NRXN3,CNTFR,GREB1,CTNND1,CYBB,DMD,DNAH9,AASS,FLT1,GFAP,CRCP,RAB30,GPER1,GRIN1,KAT7,BRINP3,KCND1,KCNJ5,KCNJ10,KCNN1,L1CAM,LAMA2,SMAD9,MYH7,NEUROD2,PCDH9,PLP1,PRRX1,IQSEC3,RGS4,RGS12,SCN7A,PPM1E,FNDC3A,SLC6A8,SLC12A4,SP4,VAMP1,MCF2L,PSD3,CDH22,THRA,TJP1,TMOD1,VSNL1,SLC30A3" Coexpression M19384 "Genes up-regulated in mouse stroma of pancreatic adenocarcinoma zenografts after treatment with HhAntag, a hedgehog (Hh) pathway inhibitor." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.62E-07 3.03E-03 1.34E-05 1.33E-04 48 149 "ADD2,KIAA1324,DPP10,STK33,BCHE,BMP7,MAP7,NOG,SUMF2,MFSD4A,ARRDC4,GPHN,TMEM107,APOPT1,NSG1,GLI2,GRIA2,WIF1,HNF4G,BRINP3,KCNJ3,KCNMA1,MBP,NTRK2,PCSK5,PENK,MASP1,RELN,BCAS3,PTCH1,PTHLH,DUSP15,RET,TMEM100,BAALC,SCN2A,TNFRSF19,ZFP2,SCG5,SLC1A3,RADIL,ZC3H13,ARHGEF12,TRPC1,TRPC3,TSPAN11,CADM2,ST8SIA2" Coexpression M19025 Up-regulated genes distinguishing in multiple myeloma (MM) samples with higher expression of TACI [GeneID=23495]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.78E-07 3.22E-03 1.42E-05 1.41E-04 103 411 "ACTN2,LTBP4,AMPH,PI16,APAF1,APOC2,API5,PPFIA3,SEMA4G,PRX,ARRB1,CDK13,AZGP1,NRP2,CACNA1I,DDR1,CALB2,CAMK2B,CLDN10,NEURL1,LARGE1,NMT2,FAM189A2,FADS2,DNAJB5,CCDC151,PICK1,AKAP7,COL11A2,TCEAL2,CRYM,KIAA0586,SGSM2,HS3ST2,DUSP9,MAMLD1,SEZ6L2,EEF1A2,EGFR,EPB41L1,DMTN,ETV1,HPCAL4,C1orf61,FOXF2,NOP56,GABBR1,GGTA1P,C1QL1,PCDH11X,GNG4,GPR12,GRB10,GRM7,GSTM5,SCRG1,TUBB2B,KCNB1,KCNH2,KIF5A,MBP,ADAM11,MITF,AFDN,MPP2,GIT1,SAMD14,MYBPC1,LINC00672,NEUROD2,NF1,NOS1,NPPA,NTRK3,KCNK10,PDE3B,GNG2,PIK3CD,PMP2,FA2H,MAPK10,GTDC1,RGS12,RNASE1,RPL38,KCNIP1,LRFN5,ITSN1,SLC1A7,PKNOX2,SLC6A8,SHANK2,SNCA,TSNAXIP1,SOX15,BEX1,SSTR2,TACR1,ACSL6,PIK3R5,FLRT2,CAMK1G,SLC4A10" Coexpression 19505326-SuppTable3 Human Ovarian_Li09_2322genes_cisplatinresistance GeneSigDB 2.96E-07 3.43E-03 1.50E-05 1.49E-04 356 1804 "SERPINA3,ACLY,ABHD6,AS3MT,ACTN1,GALNT13,ADD1,KIAA1211,RNF150,MTUS1,TBC1D14,NR0B1,SORCS2,AK2,ALCAM,SRPX,CEP126,PCDH10,ANK2,LCORL,PPFIA2,PKP4,ANXA7,APC,ALS2,TNRC6C,PPFIA3,SHTN1,LGR5,ARHGAP5,ASPH,RASL11B,DYNLL1,CHID1,ATM,ADAM23,ADAM15,CFLAR,BMP7,SYNJ1,SGCE,C5,NIPA1,RAB29,DDR1,ZNF555,CALM1,CAMK2D,CANX,CAPN3,CAST,MAP7,NFS1,PRC1,INA,CBFA2T2,SCARB1,SYNGR3,ARHGEF2,CDC42,CDH2,CDH10,LRRFIP1,CDO1,CLGN,CFL2,COPB2,B4GALT6,JAM2,SLIT2,EPS15L1,RAB28,PLAA,PPT2,TPP1,CLTB,TJP2,NIPBL,ARHGEF6,IQCK,ARMC8,SLC25A27,BTF3L4,SLC4A8,SMARCAL1,RTTN,MFSD4A,CREM,AKAP12,HAPLN1,CS,ARHGEF10,ARHGAP24,HDAC4,PHF19,TBC1D5,TOMM20,DBI,MYEF2,HP1BP3,FBXL5,MAGI2,GSDME,SACS,FAM107B,DLG3,CD99L2,NR1D2,CDON,ACOT8,ATN1,PDCD6IP,ARRDC4,DNM1L,E2F5,EDNRA,PHC2,ANKRD46,CNNM1,PHF20L1,EGFR,TMEM35A,EIF1,EPB41,EPB41L2,CD320,AMZ2,SH3YL1,ATP8A1,RACK1,ST3GAL6,CEP78,FDFT1,FGF13,FGFR1,FGFR3,FHL1,SEC23B,FOXM1,FOLH1,DPYSL4,ZNF605,CSPG5,STAU2,PNMA2,MSANTD4,AP4B1,FYN,ZMAT1,GABRA5,KIAA1841,GATM,SESN1,COPS8,GLUL,HTATSF1,KCNMB4,LNX1,GPD2,TDRKH,FUT10,GPR19,EML4,GPR37,GRB10,DIDO1,NR3C1,GSN,FAM107A,GUCY1A1,GUCY1B1,GYG1,HPS5,ZHX1,PACSIN2,MAN1B1,FRMD3,HMGB1,HMGCR,NEGR1,HSP90AA1,IDH3B,LRRCC1,IL11RA,BRINP3,ITGAV,OLFM3,LAMA2,LIFR,LMO2,NCOA7,LSS,PIK3AP1,MBNL1,IL17D,MEF2C,MID1,MKLN1,MPP2,CCDC80,PTOV1,ZNF92,SAMD14,HS6ST3,NAP1L3,NFE2L2,NFYA,CNOT4,NOVA1,NRDC,OPA1,CLDN11,PCSK5,PDCD2,PDE4A,PDE4B,PDE4D,PDGFRA,SLC10A4,PFKFB4,PFKP,SERPINE2,SERPINI1,SSH1,NOMO2,ANLN,PIK3R1,ZNF655,PKM,KCTD15,SMOX,PMP22,MAPKAP1,SCHIP1,PRRX1,ING3,SPATA6,LRRN3,PTPA,PPP2R5C,PPP3CA,PKIA,MAPK10,PRPH,GDPD1,CNNM2,NDUFS7,VPS13C,LRRC49,PSMD13,PTX3,QDPR,ROGDI,TRIM68,MORC4,RFX2,RGS10,RNH1,TMLHE,CARF,ROBO2,NEK11,RPL15,CNTNAP3,LGR4,SOX8,RTN1,SALL1,MAPK12,SEMA6D,LRFN5,SCN2B,SCP2,TNFRSF19,SEC14L1,PPP1R9A,ANKRD6,ZNF365,SLC6A8,SIRT2,SLC20A2,CPEB4,EPC1,CXXC4,GKAP1,SMARCA4,RCOR3,TTC17,SNCA,LMBRD1,PALLD,TMCC1,SPATA7,SP2,EMC1,CAND2,SPP1,PEG10,ZNF423,DBNDD2,KIF1B,COLGALT2,ITPRID2,ELOVL4,KLHL7,ARHGEF9,VPS13A,DNAJC9,ROBO3,CAMTA1,ADGRL3,TCEA1,PSD3,AP4E1,GPR161,SLC44A1,ARL10,TIAM1,HEY1,TK2,PARD3,TNS1,TPM1,TPM2,TPM3,TPM4,RGMB,PDSS1,STXBP4,TRPC1,TRPS1,FNDC5,TUBB2A,FLRT2,BCL2L13,NSD2,RICTOR,ZNF74,ZNF138,POLR3H,FSTL5,RGMA,PARP6,MDH1B,CAB39L,MPPE1,PLSCR4,FZD3,UBE3B,PHTF2,RSPRY1,RNF170,ADAMTS10,NHSL1,IFT88,NETO2" Coexpression M2129 Genes up-regulated in confluent IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.09E-07 3.58E-03 1.55E-05 1.54E-04 133 566 "ABAT,AS3MT,C3orf14,ADD1,CDC7,BEND6,MTUS1,OSBPL1A,CNTNAP1,VAT1L,SHROOM2,SLC7A14,ARRB1,B3GALT2,JAZF1,CAMK2D,RUNX1T1,CBS,CD81,CHN1,NRXN3,CLU,NMT2,TJP2,CNN3,ABI3BP,FAM171B,CLIP3,TENM4,OSBPL3,SDC3,TOX,RASSF2,PLPPR4,AK5,RABGAP1L,ARNT2,EXOG,MAMLD1,TSPAN5,TMTC1,FRY,OPTN,RGS17,TMEM35A,EPB41L2,LRRC17,KCNMB2,MRVI1,FAM198B,TUBA1B,TUBB3,PRKAG2,SCARA3,EVL,GALNT15,MTHFD2,RAB40B,TUBA1C,ADAMTS8,GSN,FRMD5,ACOT7,SYNPO,ICA1,IFI16,DIPK1A,TUBB2B,KCNH2,KCNMA1,KCNN2,MATN2,MEST,MN1,CD200,CCDC80,NFIX,NPTX1,OLR1,CLDN11,OXTR,CNTN3,NALCN,PKM,PMP22,PSAT1,MINDY2,RELN,SYTL2,PTCH1,ELOVL2,PXK,PTN,PTX3,RAP1GDS1,UBR7,RGS10,BAALC,SARS,SCN7A,TNFRSF19,PEAR1,GALNT10,DOCK10,SHMT2,FHOD3,LIMS2,SLC14A1,PALLD,DOK5,CAND2,MPRIP,SYT1,TAC3,MTCL1,ANO4,KIAA0930,SPX,C18orf54,TPM1,TPM2,RGMB,SYNPO2,TUBB2A,CADM1,ATP6V0E2,SYNC,TUBA1A,NAV3,NAV2,MSRB3,SSPN,DPF3" Coexpression M6443 Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B2 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.12E-07 3.60E-03 1.55E-05 1.54E-04 59 199 "ARID1A,ADD3,AMPD3,MADD,TMEM108,STX16,KRIT1,SCARB1,ENTPD6,CLCN4,ARMC8,NCOR1,UBXN2A,CTNND2,RIPOR2,EBF1,ERBB4,EXTL1,EVL,RAPGEF6,IQGAP2,CNTRL,PADI2,L1CAM,MARK3,MYO9A,PALM,SERPINI1,PIK3CD,PURG,PRIMPOL,PMS2,TATDN3,SLC22A23,SNRK,ARID4A,RBBP8,CCDC25,PCMTD2,SEMA6D,RASA3,PPP4R3A,CCDC88A,ZKSCAN3,TMCC1,DOP1A,KIF21B,EPB41L3,TMEM150C,ANKRD12,MLST8,SZT2,AKNA,ZMYND8,VAV2,RICTOR,AMZ1,TMEM178A,JMJD1C" Coexpression M8119 Genes up-regulated in NFKB1 and IL10 [GeneID=4790;3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]. MSigDB C7: Immunologic Signatures (v6.0) 3.12E-07 3.60E-03 1.55E-05 1.54E-04 59 199 "OSBPL1A,ZNF687,SFMBT2,TMEFF1,ADAM15,GPR146,FOXK1,CD38,CP,RBM39,PDE4DIP,PPP1R16B,MATR3,NR1D2,SEMA3D,FRY,LPAR6,TNK2,EMX2,EPB41L1,EPB41L2,ERBB2,FAM198B,FAM184B,STON1,MAEL,TOX2,GPR45,IRF8,RBPJ,IL6ST,KCNA6,IPO5,STXBP5,SMAD1,KCTD6,MYO5A,PDE3B,GPSM2,TRHDE,PTK2,RAB3IL1,RAD52,FNDC3A,ZKSCAN3,MYO16,SCN3B,CLASP2,POGZ,ERBIN,ACSBG1,C3orf70,EXOC7,CAMSAP2,TCF4,ZFP90,RGMB,AMZ1,VANGL2" Coexpression M4867 Genes down-regulated in comparison of NKT cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 3.12E-07 3.60E-03 1.55E-05 1.54E-04 59 199 "CNIH2,SEMA4G,MARCH3,ADGRB1,CDK5R2,FHL5,C1QL2,RGS6,VCAN,FAM169A,USP6NL,DCAF8,MYEF2,GUCD1,SNAP91,CCDC3,DNM1,ARRDC4,MAMLD1,DYRK1A,MRO,C8orf37,STX2,TMEM132C,CORO2B,JPH4,STARD10,ALDH1L1,GFRA1,KIAA1958,LOXL3,GRIA2,GRIK5,FAM222A,ARHGAP19,IGFBPL1,KCND2,NPY,NPTX1,PENK,CNTLN,PTPRG,GAL3ST4,GSTCD,PLPPR3,SLC30A10,TRIM46,KIF27,SMTN,LGI3,HHIP,THBS4,CDH22,TIAM1,ICAM5,SYNPO2,FLRT2,VSNL1,VANGL2" Coexpression M6757 Genes down-regulated in splenic CD 33D1+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.20E-07 3.70E-03 1.59E-05 1.58E-04 53 172 "MTUS1,KLHL13,GAS7,APOC2,DST,CD38,RCBTB2,ZFYVE9,TPP1,LY86,CP,CSF3R,PLXNA4,EDNRA,RASGRP1,GALC,HPGDS,PRUNE2,HNMT,IGF1,ITGAV,KCNJ10,TTYH2,LIG4,SCAMP5,ADAM22,LAYN,MYO7A,P2RY13,NCF2,NOVA1,OPHN1,P2RX7,SH3KBP1,PRKCB,GDPD1,RAVER2,SEC14L1,ITSN1,SLC11A1,CPEB4,RGL1,FGD4,SYPL1,DMXL2,TCF7L2,GZF1,LRRC8A,NPL,P2RY12,ZFAND5,EVI5,SNX27" Coexpression 19303107-Table3 Mouse Bladder_Price09_85genes GeneSigDB 3.70E-07 4.28E-03 1.83E-05 1.82E-04 30 76 "ALCAM,WASF1,CDH2,SLIT2,HAPLN1,TENM4,VCAN,BRINP1,HEPH,NTM,ARNT2,EDIL3,EPHB1,FOXM1,MEGF10,GABRA4,CHL1,KIT,MYO6,NASP,PTN,ZFHX4,SOX11,CAND2,SEPT3,ZFPM2,TRO,AMOT,PCBP4,VANGL2" Coexpression M9186 Genes up-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.76E-07 4.35E-03 1.83E-05 1.82E-04 59 200 "KCNH8,ASPHD1,ACTN2,ADD1,NME5,CALB1,HAP1,CAMK2B,KRIT1,FMNL3,CDH18,FAM189A2,CNTNAP2,ST18,SNPH,DNAL1,TMCC2,RPS6KL1,DPP6,ABCC5,EIF4G2,TACC2,GABRA3,ARPP21,TCERG1,PRUNE2,GPR45,INPP5B,KCNJ11,KCNN1,KTN1,MATN2,TAGLN3,NRGN,PNMA3,PPM1B,PPP2R2B,CNTLN,PTPRG,PYGM,MEG3,FOXRED1,MRAS,SLC1A2,SLCO1A2,ZNF423,SSPO,ST5,STAC2,SYT1,MTCL1,SEMA4A,TBX15,TTC3,OSBP2,TSPAN11,ZFP37,PARP11,NETO1" Coexpression M9285 Genes down-regulated in CD8 T cells 6 days after immunization: control versus IL2 [GeneID=3558] treatment. MSigDB C7: Immunologic Signatures (v6.0) 3.76E-07 4.35E-03 1.83E-05 1.82E-04 59 200 "ACTN1,ZNF608,SEMA7A,EPB41L5,DGKD,APP,ARHGAP5,DPY19L3,CDK5R1,SYNJ2,LDLRAD4,DDR1,MAP7,CD81,MAP4K4,AKAP12,LRIG1,USP6NL,GPRASP1,TOX,SPOCK2,DLG3,RASGRP1,EGR3,LRRC23,ZMAT1,GPM6B,TOX2,SYNPO,AGFG1,IL6ST,KCNC2,KIF5C,MATK,CD200,BCO1,NFIX,NUCB2,P2RX7,RETREG1,PLCL1,PACSIN1,PPM1B,TMLHE,PEAR1,ST6GAL1,ANKRD6,FAM81A,KIF13A,CABCOCO1,TCF7,TGFBR3,TIAM1,TPD52,TTC3,ZNF24,TUBA1A,NAV2,CERS6" Coexpression M6554 Genes down-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 3.76E-07 4.35E-03 1.83E-05 1.82E-04 59 200 "HACE1,CARNS1,APBB1,ARHGAP5,EIF4G3,STX16,BACH1,LDLRAD4,CACNA2D2,CLCN4,PCYT1B,SH2B1,PDE4DIP,HDAC9,IP6K1,RABGAP1L,CPEB2,SLC43A2,PRKAG2,SUCO,ZNF274,GLUL,B4GALNT4,ATG4C,HNRNPK,L1CAM,PAXBP1,GPR155,MAN2A2,MATK,MATN2,ZNF862,PIK3R1,PLCL1,ANKRD16,PTPN13,ARID4A,BSDC1,RFX3,CYB561D1,MCMBP,RYR3,PEAR1,SCAF8,ANKRD6,MPRIP,STX1A,ACSBG1,C3orf70,FBXW11,TRIM2,ARHGEF12,AKTIP,TIAM1,TUBB2A,MICU3,MSRB3,FRMD6,RNF146" Coexpression M5299 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 40 h. MSigDB C7: Immunologic Signatures (v6.0) 3.76E-07 4.35E-03 1.83E-05 1.82E-04 59 200 "RALGAPA1,ASIC1,ADD3,AMT,DGKD,KIAA1614,NCOA1,ATP6V0A1,CHI3L2,CPS1,IPCEF1,DCAF4,RIPOR2,MYEF2,USP3,EEF1D,USPL1,RASGRP2,ADGRV1,FABP7,FCGRT,FYB1,USP19,PPARGC1A,GRIN1,LINC00667,IL11RA,KCNH2,AFF1,MXI1,MYCN,GPR88,PDE1A,PLCD1,PLIN1,PDZRN4,PTCH1,PTPRE,RAD52,ZNF331,ATXN7,SGK1,CLSTN1,PREX2,SLC8A1,TTC17,ZBTB43,RAP1GAP2,MCF2L,CNTN2,ATMIN,PHF24,KAT6B,CADM1,WNT7A,WIPF2,MARCH8,NLRP3,DPF3" Coexpression M18095 Up-regulated genes from the set G (Fig. 5a): specific to cells expressing both MLL-AF4 [GeneID=4297;4299] and AF4-MLL fusion proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.32E-07 5.00E-03 2.09E-05 2.08E-04 67 238 "KDM5D,SORCS1,SPARCL1,SYT13,PHYHD1,APP,NIPA1,CBR1,KYAT1,P2RX6,UBE2L6,CHGB,TMEM59L,FAM189A2,IGDCC3,CHD1L,CRMP1,PHF14,CTNND2,ST18,IRAK4,SRPK3,EPB41,NCALD,DUSP27,NSG1,GAP43,INPP5K,GPR162,LYVE1,GNG4,PTPN5,NEGR1,IGF1,ITIH2,MAPT,SESN3,LYRM9,LINC00672,NF1,ANLN,ST8SIA5,POU3F2,RELN,LRRC49,SYTL2,GDPD2,PTPRO,EMID1,DOCK10,TET1,ABTB1,PALLD,ENKUR,PEG10,SYT11,SMG6,LRRC8A,DAAM2,TTC3,UCHL1,FRRS1L,LYPD6,CELF4,SPIRE1,DOCK8,KAT6A" Coexpression 19837975-TableS1 Human Leukemia_McWeeney10_885genes GeneSigDB 4.45E-07 5.15E-03 2.15E-05 2.13E-04 135 580 "ABAT,SLC44A5,KLHL13,TAOK1,FAM135A,GPRASP2,OGT,LCORL,APC,SHTN1,PDXK,MPDZ,BMPR1B,CBFA2T2,TIGD7,B4GALT6,LY86,HOMER3,SLC25A27,FAM171B,PDE4DIP,SLITRK5,HDAC9,RIPOR2,IST1,DAPK1,KIAA0087,ARMCX4,ARMCX2,TIAM2,SPOCK3,RAB39B,DMD,USP3,CALN1,ATL1,ANKRD46,FEM1B,FSD1L,RBM12,KMT5B,LPAR6,POLR1B,FGR,FHL1,NBEA,ATP6V1H,ZNF605,GAB1,ZNF44,DISC1,FREM1,HPGDS,LNX1,PRDM5,GUCY1A1,GUCY1B1,IRAK3,HBA1,BACH2,HLF,HMGCR,KLHL23,STXBP5,LMO2,VWA5A,MAT2A,MEF2C,MEIS1,BEX5,NAP1L2,NAP1L3,NFYA,NRDC,P2RY1,PBX1,PCDH9,PDCD2,TMOD2,CCSER2,RC3H2,SPATA6,KANSL1,RASGEF1B,SLC26A11,PTPN13,PTPRE,PYGM,RFX3,TTLL7,SLC25A36,CARF,ROBO1,MEG3,SATB1,FNIP1,KIF21A,PPP1R9A,SH3GL3,DOCK10,ANKRD6,SLC8A3,SLC22A4,LIMCH1,TMCC1,FNBP1,SPP1,ZC3H13,ZBTB43,NKAIN2,CEP68,ANKRD28,TBCEL,TCF4,TCF12,ZMAT3,AKTIP,ARL10,TRPS1,SSBP2,TTC3,TUBB2A,ZNF17,ZNF23,MICU3,TCEAL7,ZBTB38,ZNF189,TMEM178A,TMEM163,TRIM16L,PLSCR4,RSPRY1,TTC7A,KLHDC1" Coexpression M372 Genes down-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 4.65E-07 5.38E-03 2.23E-05 2.22E-04 49 156 "ACTN1,GRAMD1B,OGT,SFMBT2,ARRB1,INSYN2B,EIF4G3,NIPBL,ENTPD4,SOCS5,TOX,TBC1D5,ARMCX2,RABGAP1L,DOCK2,MBNL2,KMT5B,PLEKHA1,WAC,ATP8A1,EVL,GABBR1,NEU3,RAPGEF4,BACH2,IL6ST,WDR49,P2RX7,SIDT1,PTPN13,RIC8B,PCMTD2,RIMKLA,CHD9,WDR37,ZKSCAN3,KIF13A,MYCBP2,SMG6,TCF7,TCF12,SYNE1,NSD1,BHLHB9,SSBP2,RICTOR,KCNAB1,ST7,JMJD1C" Coexpression M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.69E-07 5.43E-03 2.24E-05 2.23E-04 98 390 "SERPINA3,SYN3,ADORA2A,ADGRF5,SRPX,IGDCC4,DDX3Y,ATP1A2,RGS11,NRP2,CALM1,CH25H,CDC25B,CFL2,DNAJB5,CNN3,WHRN,ABI3BP,CNRIP1,AKAP12,LRIG1,MICAL2,PPP1R16B,SDC3,CYBB,MYADM,TOX,SIRPA,DOCK2,DPYSL2,ECM2,EBF1,EDIL3,EDNRA,HEYL,TMTC1,EBI3,ELN,EPB41L2,RCAN2,ETV1,RTN3,NRN1,EFEMP1,AMOTL2,FHL1,FOLR2,FYB1,FYN,DKK3,NEK6,IQGAP2,MALT1,GPM6B,GSN,GUCY1A1,HLF,SYNPO,LIG4,AFF1,CCDC80,MYO5A,DDR2,NUMA1,PDE1A,PDGFRA,PIK3CD,PMP22,PRRX1,SH3KBP1,MAPK7,PTK2,C1orf54,RGS10,SEMA6D,SELL,STUM,ST6GAL1,EFHD1,CMTR2,PALLD,PDZRN3,SON,SAMSN1,RGL1,TACC1,TCF4,TCF7,FAM200B,DAAM2,TNS1,TPM1,TPM2,LAT2,ZFAND5,ADAMTS9,PHTF2,TTC7A" Coexpression 20599952-Table1 Human BoneMarrow_Maisel10_105genes GeneSigDB 5.10E-07 5.90E-03 2.43E-05 2.41E-04 37 105 "ABAT,PROM1,PRC1,CLU,FEZ1,EDNRA,ELN,TUBB4A,GAP43,GPM6B,GPR17,GPR37,STMN2,LAMA2,MAG,MBP,MOBP,MOG,NKX2-2,PCDH9,PCSK1,PDGFRA,PLP1,SEPT4,KLK6,PTCH1,PTX3,BAALC,S100B,SCG5,EFHD1,SPP1,TAC1,TF,TPM1,TPM2,NETO2" Coexpression M13206 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.16E-07 5.97E-03 2.45E-05 2.43E-04 85 326 "ABAT,XKR4,FMNL2,SPARCL1,IGDCC4,DACT3,ATP2B1,MYOM1,DST,CAMK2D,DCLK1,LRRFIP1,FOXN3,MAGED1,NCOR2,CLIP3,CST3,BOC,TOX,JAKMIP2,ZNF804A,RHOBTB1,DLX1,CDON,EBF1,SEZ6L2,SIDT2,LPAR6,ING4,MFSD10,LRRC17,EYA1,DLC1,BAIAP2,AMOTL2,KCNMB4,GNAS,ATP2B1-AS1,GSN,ATOH8,IGFBPL1,IL11RA,LMO2,MAP2,MEF2C,AFF1,CCDC80,NBL1,NFIA,ZNF827,ENPP2,SMOX,PCDH18,RETREG2,FAT3,LRRN3,PTH1R,PTX3,PID1,C1orf54,RGS3,ELP2,SATB1,PPP1R9A,ANKRD6,FAM214B,SLC20A2,LIMCH1,ZCCHC24,DOK5,ZNF423,SPTAN1,ZBTB43,TSPYL2,LMO3,PHLDB1,SULF2,MLC1,TCF7L2,TGFBR3,TRO,RPRM,UBE2H,ITM2C,FRMD6" Coexpression M2142 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.22E-07 6.04E-03 2.47E-05 2.45E-04 45 139 "KCNH8,OSBPL6,SPARCL1,ANK2,DCLK1,RAB3C,B4GALT6,NRXN1,OSBPL3,EDN3,EEF1A2,EPS8,TMEM74,PDLIM5,TRAF3IP2,GAD1,GAP43,PCDH17,GLS,GNAS,GPR22,GRIK2,GUCY1A1,ARHGAP36,IFI16,IGSF1,STXBP5,MAP2,SESN3,HS6ST3,NRCAM,RETREG1,RELN,ATXN1,SOX6,HSPA4L,TNIK,ARHGAP26,CLSTN2,NXT2,HHIP,NACC2,HEY1,FSTL5,SCG2" Coexpression M6878 Genes down-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il. MSigDB C7: Immunologic Signatures (v6.0) 5.29E-07 6.12E-03 2.49E-05 2.47E-04 54 179 "AXIN2,SYT13,PITPNM2,SEMA7A,SFMBT2,ARRB2,BMP7,DST,METTL6,CD81,CDH10,ZMYM4,MAGED1,CLOCK,LRIG1,CTNND1,TOX,FAM107B,RASGRP1,MBNL2,ABI2,PTK2B,FGF13,EVL,FYN,RAPGEF6,NEU3,GFRA1,GPM6B,FUT10,AGFG1,IL6ST,JAK2,SLC35G1,HECTD2,ARHGAP12,KCTD6,SESN3,SLC11A2,P2RX7,PLCL1,SH3KBP1,DRAM2,EPDR1,PTPN13,RFX3,RGS10,KCNIP2,DZIP1,SLA,USP33,CAMSAP2,DOCK9,TTC3" Coexpression M2605 Genes down-regulated in uveal melanoma: class 2 vs class 1 tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.78E-07 6.69E-03 2.71E-05 2.69E-04 124 525 "ABHD6,C3orf14,ADCY6,ADD3,ADRB2,MTUS1,SEMA6A,TMEFF1,ZSCAN18,AZGP1,NRP2,GYG2,ENTPD6,ZBED1,TPP1,NMT2,TJP2,CNN3,LETMD1,CPS1,PREPL,APPL1,CTH,SEC14L5,HDAC9,TOMM20,IP6K1,SIRPA,ARMCX2,DCT,RABGAP1L,DMD,DPP6,DPYSL2,EDNRB,MBNL2,LPAR6,EIF4G1,PCOLCE2,ETV1,GMPR2,ECSIT,WAC,TUBB4A,DLC1,ST3GAL6,FDFT1,SORBS1,GPR153,NSG1,OGA,FYN,GALC,ALDH1L1,SPIN1,GLUL,GNAS,NUDT21,GPR37,PCLO,KIF3A,HNMT,IL11RA,ITPKB,IPO5,VWA5A,MATN2,MBNL1,MEST,CD200,NAP1L1,NAP1L2,PBX1,DPY19L2P2,PDE4B,PDE4D,ENPP2,SERPINI1,PIK3R1,PMP22,ING3,PRKACB,MASP1,SNRK,PEX5,FAM184A,SLC6A15,SLC25A36,ZNF532,ROBO1,RPL15,RYR1,SATB1,ATXN7,SYBU,SNCA,ZNF415,PALLD,CAND2,SPP1,ERC1,PEG10,ZNF423,ZC3H13,BEX1,SS18,NEK4,ATP11A,PSD3,AHCYL2,GPR161,ZMAT3,MTMR14,TJP1,TLR4,BEX4,SSBP2,GORASP1,ZBTB38,CSDE1,PLSCR4,EPM2A,HRASLS,FXR1" Coexpression M19062 Genes up-regulated in nasopharyngeal carcinoma (NPC) compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.03E-07 6.98E-03 2.81E-05 2.79E-04 354 1805 "ABAT,ASIC1,ABHD6,NDRG2,ADARB2,KLHL32,ADCY2,HHATL,PLEKHH1,ADORA1,SLC24A4,NME5,OSBPL6,CC2D2A,HFM1,CEP126,MARCH4,KCNT1,KIF6,FGD2,C6orf89,CCDC146,SUGT1P4-STRA6LP-CCDC180,DGKD,FAM131A,PHYHD1,BCAS1,AQP4,KIAA1614,STK33,NUMB,CCDC181,ATP1A2,TTLL9,DCAF5,ZNF599,PROM1,BMPR1B,CASTOR3,CACNA1I,BAIAP3,CFAP410,CA12,CALM1,KALRN,CAMK2G,TRIM41,SLC25A14,CAST,CH25H,RUNX1T1,CLDN10,USP2,LRRFIP1,ZNF445,MAGI1,LRWD1,FOXN3,CASC2,RPL32P3,NRXN3,CLCN4,CLU,HECTD1,CCDC151,FAM149A,ANKRD35,TOGARAM2,MFSD4A,CP,PNKD,CDC42BPB,CRY2,GDA,CRYM,MROH8,SIPA1L1,DZIP3,PITPNM3,CTH,CFAP61,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,KIAA0513,SCRN1,DNAL1,ELMSAN1,C8orf34,C2CD2L,KIAA0319,KLHL3,SPOCK3,FAM107B,KIF19,ZNF582-AS1,DNAH9,SLC12A6,ACOT8,PDCD6IP,GNE,TOM1,EBF1,SNX29,ATL1,COPS4,EPB41L1,LRRC23,RASGRP2,KCNMB2,ERBB2,CDHR1,ANKMY1,EYA1,F3,ABCA8,TUBB3,ZMYND10,FECH,FGF14,BAIAP2,AMOTL2,CAMSAP1,FHL1,SCARA3,IQCG,ATP13A4,FOLH1,EFCAB2,NBEA,TACC2,TMEM107,TPPP3,SDCBP2,GAB1,CHL1,GALC,TMEM8B,DNER,GATM,ALDH1L1,GPR162,USP19,GGT7,GJB1,GK,TOX3,GLUL,GNAL,GPT2,LNX1,PRUNE2,TPPP,DIDO1,SPACA9,SERP2,CACFD1,ADAMTS8,GRM5,GRM7,PTPRT,GSN,COQ10A,TMEM25,FAM107A,HLF,HMGCL,CFAP126,USP51,KNDC1,SCIN,KCNB1,KCNJ16,DPP10-AS1,LMO2,SYTL4,VWA5A,PACRG,ZNF667-AS1,C1orf194,MAOB,MAP6,MBP,CHST6,EFHB,MEF2C,MEIS1,MEIS2,AFDN,WDR49,ERICH3,COL28A1,CCDC80,MSI1,STK32C,MSRA,MT1M,MT3,LAYN,NEXMIF,NBL1,IDNK,CCDC13,NF1,NFIA,NFE2L2,PCBP3,NUCB2,ODF2,OGG1,OXTR,PCDH9,PCSK5,ABCB1,DUSP26,ZFYVE21,PLXNB1,SPATA6,EPB41L4B,FA2H,VSTM2L,PRKCZ,MAPK3,GRAMD1C,HYDIN,MASP1,SYTL2,DEF8,SNRK,QRICH1,WDR25,PXK,PTPRH,PTPRN2,PTPRO,TMEM231,ZNF844,CCDC40,FAM184A,ZCWPW1,BEND5,RFX2,RNH1,MYH14,EXD2,RORB,MRAP2,SNX22,NEK11,ARMH4,BAALC,RPS6KA2,PLPPR3,HSD11B1L,ST6GALNAC6,WLS,TMEM156,TNFRSF19,SMPD3,ASRGL1,KIF21A,FAM102A,SH3GL3,ARX,ASAP3,CPEB3,MAGI3,BCAN,LINC01354,SYBU,ST3GAL3,ABLIM3,EPN2,SLC6A11,SHANK2,SLC15A2,BTBD7,SLC20A2,SLC22A4,ZNF667,INAVA,CABCOCO1,ANKFN1,PDZD2,WDTC1,SPATA7,TSNAXIP1,CLUAP1,ENKUR,CAND2,ATP10B,LRRC4,NACAD,ARHGEF26-AS1,ADHFE1,ACSBG1,COBL,KAZN,MCF2L,PDLIM2,WWC1,VWA3A,SYNE1,DOCK9,CCDC173,RNF175,SIK3,CYB561A3,DNAH7,DICER1-AS1,TMEM121,LEFTY2,ZNF106,THRA,HEY1,TIMP4,TK2,ASXL3,LRRC8A,TNS1,CDK20,PRMT8,RUNDC3B,PPIL6,PRR18,TUBB2A,TMEFF2,UBTF,GORASP1,ZNF709,CCDC136,SLC13A3,CFAP298,PCDH20,ZBTB14,ZNF19,CFAP52,ZBTB38,REEP1,EML6,PROCA1,DNALI1,GDPD5,RNF103,TUBA1A,MDH1B,DNAH10,FAM182B,FBXO36,NUP214,FAM219B,TTC7A,IFT88" Coexpression 15220918-TableS1a Human Viral_Wang04_1482genes GeneSigDB 6.05E-07 6.99E-03 2.81E-05 2.79E-04 244 1178 "ABHD6,ACTN1,ADD1,ADD3,AP2A2,ADGRF5,SEMA6A,SPOP,BBOX1,BIN1,CDC42BPA,ANK3,DGKZ,DGKD,API5,APP,ARHGDIA,ARRB1,PLA2G4C,ASPA,ATP2B2,ATP6V0A1,KIF1A,AZGP1,ADGRB2,MPDZ,BID,ARHGEF7,FUBP1,SCAPER,RAB29,BTRC,CA12,DDR1,THSD7A,CALM1,HIP1R,MAP7,LDB2,CD81,CDC25B,CDC42,DLGAP2,UBE2L6,TAOK2,TPP1,CLTA,CLTB,CLTC,QKI,MAP4K4,RAB26,HOMER3,ARHGEF6,MAGED1,IFFO1,CREM,AKAP12,FEZ2,FEZ1,MICAL2,VCAN,CST3,DZIP3,PPP1R16B,SDC3,DCAF4,RUBCN,DOCK4,ARHGAP32,ZFYVE16,RIMS3,SCRN1,IP6K1,DBN1,PITPNC1,ELMO1,B3GAT3,KLHL3,RHOBTB1,SV2B,SRGAP3,KBTBD11,DNAH9,DPYSL2,ACOT8,DTNA,EDNRA,EFNA3,EGFR,SORBS3,EIF5,PLEKHO1,MFSD10,EPB41L2,EPS8,EFS,ANKMY1,RASL12,CACNG3,TUBA1B,DLC1,CHST15,FCGRT,TESK2,OLFM1,CAMKK2,CELF1,FYN,DENND2A,GAD1,GAD2,IQGAP2,ERAP1,MTHFD2,SEPT9,ALDH1L1,CYP46A1,NFU1,PCDH17,LYVE1,COPS8,OS9,FERMT2,GPD2,GPM6B,GPR37,GRB10,GUCY1A1,GUCY1B1,GYG1,SYNPO,IFI16,IGF1,IL6ST,ITPKB,JAK1,LMO2,LSAMP,SMAD1,SHC3,MEF2C,MEIS1,AFF1,CD200,ADAM22,MYCN,NAP1L1,FXYD6,NF1,SLC11A2,NUCB1,OCRL,PAX6,PBX1,PCSK2,PDE1A,PDE2A,SSH1,SNX10,GPSM2,PCDHB17P,MASP1,CNNM2,GDPD2,PTK2,PTPRB,PTPRE,PTPRN2,PTPRZ1,RIPOR1,PPP2R3C,RAD17,RAP1GDS1,ZDHHC14,RGS3,RGS4,RNF220,RNASE1,ZNF532,RPS6KA2,STK32B,EMID1,KCNIP1,CLIP1,RTN1,FOXRED2,SEC14L1,GALNT10,SFPQ,HSPA4L,ITSN1,ASAP3,SHMT2,FNDC3A,CCDC92,ABLIM3,SLA,SMTN,CCDC88A,SNCA,SOX15,GLT8D1,ZBTB43,SRPK2,ATP10B,EPB41L3,MPRIP,STAU1,APOM,RGL1,TACC1,SEMA4A,TAL1,WWC1,MGRN1,TCF4,ZEB1,USP22,PCDHGC5,PHF24,TNS2,PCDHA2,TIAM1,TIE1,HEY1,TLL2,PARD3,TPD52,TPD52L2,TRIO,TSN,FLRT2,TBC1D15,VSNL1,WIPF1,CLIP2,REEP1,ANKS1B,GDPD5,TUBA1A,PAK5,FAM182B,PHTF2" Coexpression 16488994-SuppTable1b Mouse Lung_Lu06_856genes_Array MEO430Av2 GeneSigDB 6.18E-07 7.15E-03 2.86E-05 2.84E-04 108 443 "ADCY2,ADCY8,ADORA1,ADRB2,ALCAM,LTBP4,ANK1,PKP4,GPAM,ARRB1,NUMB,ATP1A2,MPDZ,PROM1,BTRC,CAMK2D,LRBA,ADGRG1,RAB28,PLAA,CLU,HOMER3,CNTN1,COL4A5,AKAP12,CSF1,CSNK1E,VCAN,CTNND1,SIRPA,EDN1,EGFR,SORBS3,RASGRP2,EFS,F5,FECH,FER,FGFR1,FHL1,FLT1,FYN,DKK3,GAB1,ZMYND11,GAP43,SESN1,GFRA1,GGT5,LYVE1,GJB1,CRCP,FERMT2,LNX1,GP1BB,RAPGEF4,STMN2,GRIA1,GUCY1B1,HP,IGF1,IL6ST,ITGA7,ITPKB,KCNH2,KCNK2,KIT,LAMA2,MBP,MITF,MYO6,MYO7A,NBL1,NRGN,DDR2,P2RY1,PALM,PCSK5,PDGFRA,GNG2,PLP1,PMP22,PPP2R5C,RELN,PTPRB,PTPRD,PTPRE,PTPRZ1,ROGDI,RASGRF2,DPF2,RGS4,RGS10,ROBO1,RPS6KA2,RTKN,MRAS,SPP1,TNS2,PCDHA1,TEK,ZMAT3,ZNF106,TIE1,BEX4,TNFRSF1B,AMOT,SSPN" Coexpression M8124 Genes up-regulated in basal subtype of breast cancer samles. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.31E-07 7.30E-03 2.91E-05 2.89E-04 147 647 "TTYH1,ACTN1,NDRG2,ADCY2,ADD2,FZD9,AK2,BBOX1,APBA2,LGR5,PDXK,TMEFF1,RGS20,DNAH17,KIF1A,PROM1,MTMR2,CACNA1A,CALB2,CBS,CLDN10,CCKBR,CD38,CDH2,CRLF1,CHI3L2,PLEKHB1,LHX2,CLCN4,QKI,HOMER3,CNN3,COL9A3,COL11A2,TCEAL2,CP,HAPLN1,SUSD5,NCAN,TOX,DBN1,DNAJC6,HEPH,CEP170,LYPD1,TMCC2,DYNC1I1,RCAN1,DUSP9,EDN1,EGFR,PCOLCE2,ELN,EPB41L2,NCALD,EXTL1,FABP7,ST3GAL6,UBE2E3,SYNCRIP,IQCG,FOXM1,FOLH1,KHDRBS3,FUT9,MPP6,DENND2A,GART,TXNL4A,GLDC,GLS,PCSK1N,GPM6B,GPR19,GPR37,FAM107A,SLC2A6,WIF1,PADI2,SCRG1,AGBL5,IFI16,TUBB2B,ITPKB,KIT,L1CAM,MAP2,MDFI,MID1,NCAM1,NEFH,NFIX,NPTX2,PAX6,PDGFRA,PFKP,GPSM2,LRP12,PSAT1,SCHIP1,MAPK8,KLK6,PTPRZ1,PTX3,SLC6A15,NUDT11,ZNF532,KIRREL1,TMEM100,TCP11L1,RYR1,S100B,MRAS,TRA2B,HSPA4L,PPM1E,FERMT1,ST8SIA1,DZIP1,CCDC88A,INAVA,SOX10,SOX11,SOX15,EMC1,CAND2,SPP1,PEG10,ELOVL4,KLHL7,MLC1,ARHGEF9,ATP11A,TRIM2,PCDHB3,LEFTY2,GPR161,TPM2,TSN,UCHL1,UGT8,VLDLR,NSD2,ZIC1,LRP8,ITM2C,HRASLS" Coexpression M2726 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v6.0) 6.79E-07 7.86E-03 3.12E-05 3.10E-04 57 194 "SERPINA3,ABAT,KIAA1324,ALCAM,PKP4,APBB2,SHROOM2,CASK,ASCL1,ZBTB10,MPDZ,CA12,CALB2,PTBP2,ADGRG1,COL9A3,LRIG1,GREB1,GAPVD1,ARNT2,RASGRP1,EGR3,EPB41L2,TBC1D16,DLC1,CHST15,GALC,WASF3,GFRA1,GHR,SPIN1,GPD2,GPER1,DIDO1,JAK2,KITLG,MXI1,FAM216A,FTO,PMP22,EPB41L4B,SYTL2,SIDT1,ELOVL2,ROBO1,PPM1E,BTBD3,PALLD,SOX3,PLCB1,SATB2,TCF12,TRPS1,DNAJC12,ZNF32,FTSJ1,JMJD1C" Coexpression 15902281-TableS1a Human Leukemia_Schoch05_1052genes GeneSigDB 6.84E-07 7.91E-03 3.13E-05 3.11E-04 109 449 "ADCY8,MTUS1,ANK1,RGS20,ASPH,ZBTB10,MTMR9,ADGRB1,FGF17,OSGIN2,CA8,CALB1,RUNX1T1,MTMR7,MYOM2,DLGAP2,CLU,BAG4,ENTPD4,ARHGEF10,RIMS2,ST18,TOX,PHYHIP,FBXO25,KBTBD11,TRAPPC9,DPYSL2,E2F5,ANKRD46,EEF1D,PHF20L1,EGR3,GOLGA7,SORBS3,VPS13B,DMTN,NCALD,EYA1,PTK2B,DLC1,FDFT1,FGFR1,SCARA3,FAM49B,ATP6V1H,KHDRBS3,STAU2,PNMA2,SARAF,ADAM28,GFRA2,FUT10,STMN2,HAS2,ZHX1,HNF4G,KCNQ3,MATN2,MMP16,MSR1,MSRA,NEFM,SNTG1,ENPP2,PENK,DUSP26,PLEC,PURG,PMP2,LRP12,PPP3CC,PKIA,PTK2,PEX2,OXR1,ZMAT4,ZFHX4,CCDC25,BAALC,RPS20,PUF60,R3HDM2,SYBU,SLA,PREX2,SLC20A2,LGI3,INTS9,ARC,TACC1,DDHD2,PDLIM2,UNC5D,RALYL,PSD3,TEX15,ZFPM2,ZNF34,HEY1,CSMD1,TPD52,TRPS1,TTPA,SGK3,WRN,STMN4,FZD3,RNF170" Coexpression M12763 "Genes depleted in embryonic, neural and hematopoietic stem cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.89E-07 7.97E-03 3.14E-05 3.12E-04 29 74 "ABR,AP2A2,BIN1,KCNAB2,GAS7,LY86,COL11A2,CSF1R,CST3,SIRPA,RTN3,ST3GAL6,EVL,B4GALNT1,GRIA2,GSN,STMN1,NCAM1,PACSIN1,PPP3CA,PRKCB,RELN,ROGDI,ZDHHC14,RGS10,SLC11A1,EFHD1,LAT2,PLD4" Coexpression M12522 The 'group 1 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.14E-07 8.26E-03 3.24E-05 3.22E-04 124 527 "ABAT,NCKAP5,KIAA1324,OSBPL6,SEMA6A,GPRASP2,OGT,APBB2,ZBTB10,BARD1,BCS1L,DST,RAB29,WASF1,CA12,VXN,ARHGEF2,CDC25B,LARGE1,EPS15L1,FAM189A2,HOMER3,COL4A5,FEZ1,ATRNL1,GREB1,RIMS2,DCAF4,TCAF1,ARHGAP24,PHF19,TBC1D5,DSCAM,DTNA,MAMLD1,FARSB,E2F6,ABI2,EGR3,ERBB4,ARMCX1,DLC1,PRMT5,OLFM1,TMEM164,FHL1,CAP2,EVL,ZBED3,GFRA1,SPIN1,GPER1,NUDT21,GRIA2,RFFL,ARHGAP36,IGSF1,ZNF385B,JAK1,IPO5,L1CAM,LAMP2,SYTL4,MAP4,MAPT,LDLRAD3,MEST,THYN1,MYO5A,NAP1L2,NRCAM,PBX1,SNX10,KCTD15,FTO,PMP22,TNPO2,PPP2R5E,SYTL2,ELOVL2,PTPRG,ACSS3,RBBP8,VEPH1,ELP2,CCDC112,SARS,ATXN1,SHMT2,SYBU,EFHD1,ZFP1,PALLD,SOX3,ZCCHC24,ERC1,CEP68,NECAB1,PLCB1,SYT1,ANKRD28,MMS19,CAMTA1,TBL1X,PCDHGA4,TIAM1,HEY2,TNNT1,TPM3,SYNPO2,METTL3,SGK3,CADM1,FAM155A,DNAJC12,VGF,ZIC2,ZNF711,LYPD6,DHX33,SLC38A1,SEMA3B,DOCK8,FRMD6" Coexpression M5208 Genes down-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 7.30E-07 8.44E-03 3.27E-05 3.24E-04 58 199 "ASIC2,SLC12A5,ADRB2,PKP4,SCAPER,SGCE,MYRF,CACNA1D,CCK,CCNT1,INA,CHGA,B4GALT6,DNAJB5,COL4A5,CRYM,AATK,FAM131B,TCAF1,FRMPD4,TMCC2,DRD1,LRRC23,RASGRP2,RRAGB,OLFM1,SEC23B,FLNC,TBR1,GABRB3,B4GALNT1,ERAP1,LPAR4,RAPGEF4,HP,BRINP3,INPP5B,ITPKB,MATN2,NOVA2,PAH,C19orf57,POU6F1,PEX2,RPE,RYR3,PPM1E,INTS9,KDM4B,SOX15,ERC1,AJAP1,MTCL1,USP22,KCTD2,TPD52,LILRA4,AMOT" Coexpression M5455 Genes up-regulated in comparison of mast cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 7.30E-07 8.44E-03 3.27E-05 3.24E-04 58 199 "NDRG2,KIDINS220,NR0B1,MYH7B,ARNTL,MARCH3,BID,CAST,RCBTB2,ZFYVE9,CLCN3,KIAA1549L,TPP1,ABI3BP,SOCS5,CTNND1,ZNF804A,SH3GLB1,PCOLCE2,EFS,EXTL2,CHST15,FOLR2,SORBS1,ATP6V1H,GABRA1,GALC,GLUL,GRB10,GSTT2,HRH3,HP,KLC1,MEIS2,MID1,AFF1,SMIM7,PTK2,PTX3,SUPT20H,R3HDM2,EPN2,ZKSCAN3,FAIM2,LMBRD1,ZCCHC24,SAMSN1,SST,CAMTA1,PCDHGB6,WDR7,TIE1,HEY1,TMOD1,TPM1,ZMYND8,TUBB2A,PMEPA1" Coexpression M5591 Genes up-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 7.30E-07 8.44E-03 3.27E-05 3.24E-04 58 199 "ADD3,BIN1,N4BP2L1,BID,CALM1,CAST,RHBDL1,USP6,DCLK1,ZBED5,CLOCK,PUM1,GPRASP1,ZNF337,EGFR,IRAK4,ELAVL4,PCOLCE2,EIF1,EZH1,FAM198B,SESN1,GFRA2,MALT1,DIDO1,BTN2A1,HSF2,IL6ST,IL11RA,KIF5C,MBP,MYH3,NACA,NPR2,PDE4B,GDAP1L1,MTRF1L,SDK2,PTX3,C1orf54,RERGL,CCDC102B,MCMBP,RXRA,SELL,SLC14A1,SORCS3,INAVA,PLCB1,AHCYL2,KAT6B,UGT8,WNT7A,ZNF142,ZNF184,VPS35L,HNRNPA3,JMJD1C" Coexpression M1311 Genes down-regulated in cancer endometrium samples compared to the normal endometrium. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.31E-07 8.46E-03 3.27E-05 3.24E-04 31 82 "SRPX,LTBP4,RUNX1T1,LDB2,CNRIP1,KIF26A,DPP6,ECM2,EDNRB,EFS,TMEM132C,EFEMP1,OLFM1,JPH4,ATP8A2,KLRC2,PAK3,PDGFRA,MASP1,PID1,RORB,MEG3,SIN3B,ZEB1,SYNPO2,TRO,TRPC1,FLRT2,PLEKHH2,MICU3,TCEAL7" Coexpression 16849537-SuppTable3 Human StemCell_Davicioni06_389genes GeneSigDB 7.67E-07 8.87E-03 3.41E-05 3.39E-04 83 319 "ABAT,ADD1,ADORA1,SPARCL1,ALK,ANK1,ANK2,PPFIA4,TMEFF1,ARRB1,MARCH3,BCHE,NRP2,ST3GAL5,MAP4K4,ARHGEF6,CREM,AKAP12,MICAL2,CSNK1E,SPOCK2,JAKMIP2,GSDME,RHOBTB1,ABI1,E2F5,EDN3,EDNRA,PLXNC1,LRRC17,EYA1,RASL10A,DENND2A,GAD1,GATM,MSTN,PCDH17,MSL3,GPM6B,NR3C1,HMGCR,INPP1,DIPK1A,ITPKB,JAK1,KCNH2,KCNN3,VWA5A,SMAD1,MMP16,MN1,MYCN,NEFM,NELL1,NRCAM,PCSK5,PDE4D,SERPINE2,PRRX1,EPB41L4B,LRRN3,PKIA,SPDL1,PTPRE,MORC4,STK32B,MEG3,SATB1,SCN3A,GALNT10,SGK1,SCN3B,TNIK,SOX11,NFASC,COBL,TCF4,TCF7L2,WDR7,DICER1,TPM4,CADM1,REEP1" Coexpression 17284527-TableS1 Human Lypmhoma_Leval07_644genes GeneSigDB 8.31E-07 9.61E-03 3.68E-05 3.66E-04 117 492 "SERPINA3,KDM5D,XKR4,RNF157,ADD2,ESYT2,KIAA1324,OSBPL6,SRPX,ASCL1,CCDC74A,DDX3Y,EIF4G3,CDK5R1,ARHGEF7,CA8,CDO1,CHGB,CHN2,MS4A7,TMEM155,CP,VCAN,FAM169A,CTNND2,PITPNC1,GSDME,FAM107B,CHRDL1,DMD,HS3ST2,FCF1,EPB41,RCAN2,EPHB1,ETV1,SIRPB1,NRN1,ACSL4,EFEMP1,ATP8A1,FCGR1A,FGF13,SCARA3,NPTN,FYB1,SEPT9,LYVE1,HPGDS,GNG4,EML4,IRAK3,HAS2,FRMD3,BACH2,VSIG4,IGF1,IL6ST,JAK2,KCNK1,KCNN3,PIK3AP1,MATN2,MBNL1,MEST,PPM1L,CD200,SESN3,MT1M,NELL2,NOVA1,NTRK2,PDE4B,PDE4D,ABCB1,SERPINE2,PIK3C2A,CCSER2,RETREG1,PLCL1,PLIN1,PILRA,KANSL1,PTCH1,PTPN13,PTPRN2,MARCH1,RGS4,GLDN,LRRK2,SOX8,S100B,SATB1,ATXN1,SCN3A,FNIP1,SLC1A2,FAIM2,SPP1,KDM4C,PEG10,NFASC,EPB41L3,MLC1,TMEM150C,SATB2,PCDHAC2,GPRIN3,SIK3,UBE2H,UCHL1,P2RY12,ANKS1B,TMEM163,FZD3,JMJD1C,VANGL2" Coexpression M11615 Genes down-regulated in metastatic tumors from the whole panel of patients with prostate cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.52E-07 9.85E-03 3.73E-05 3.71E-04 80 305 "SYS1,AXIN2,FAM135A,EPB41L5,CACHD1,BCAS1,DACT3,ALDH7A1,AZGP1,BMP7,CACNA2D1,CD38,CDH10,CFL2,FOXN3,SLIT2,ARHGEF10,BOC,SPOCK3,EGR3,PCOLCE2,HSD17B14,ERBB2,EFS,RASL12,MRVI1,ARMCX1,FGF13,PSD2,SORBS1,POMT1,ZMYND11,GHDC,IQGAP2,GSTM5,FAM107A,LSAMP,PPM1L,MN1,MX1,NBL1,IDNK,NEFH,NFIA,NINJ2,DDR2,CNTN3,PDE4B,PCDH18,PDZRN4,PRRX1,PPP3CB,PTN,PTPRN2,ROGDI,GTDC1,ZNF532,ROBO2,SCN7A,ASAP3,FHOD3,SMTN,LIMS2,SLC15A2,SLC20A2,SOX2,LHPP,MIR100HG,TMEM150C,PSD3,THBS4,TNS1,SYNPO2,RBFOX3,SLC30A4,PMEPA1,DNALI1,CAB39L,MVB12B,SSPN" Coexpression M2020 Genes with high-CpG-density promoters (HCP) with unmethylated histone H3 in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.65E-07 1.00E-02 3.73E-05 3.71E-04 64 228 "GPR158,NR0B1,CNIH2,APOC1,CAMK2A,RHBDL1,DLGAP1,CHRM4,SYNPR,COL9A3,ZNF385A,CNTNAP2,NRSN1,CHRDL1,DPP6,EDN3,RAB9B,SPEG,CLVS1,CACNG2,CAMKK2,GFAP,MAP7D2,PCSK1N,GSN,MAEL,NXPH2,HTR5A,IGSF1,OLFM3,CLVS2,KCNJ11,SCG3,NOS1,HMGCLL1,POU3F4,MYH14,SCG5,ARX,RPH3A,SLC2A5,LGI3,SOX3,SOX15,SSTR2,NECAB1,SYP,PCDHB10,PCDHB7,PCDHB4,NSD1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,BEX4,CHST5,TRPC3,KCNE5,FSTL5,SPIRE1,HRASLS" Coexpression M7722 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 8.72E-07 1.01E-02 3.73E-05 3.71E-04 49 159 "FMNL2,PLA2G6,SEMA7A,DGKD,DPY19L3,PPT2,TMEM184B,LRIG1,PPP1R16B,DNAJC6,DOCK2,SLC12A6,MBNL2,PAN3,USPL1,RCSD1,IP6K2,SEMA4D,AHDC1,DIDO1,GUCY1A1,SYNPO,MBNL1,MBP,LDLRAD3,NTRK3,PDPK1,PFKFB3,PRODH,EML5,FAM161B,SATB1,SCN4B,SLC9A5,SCMH1,ARFGAP1,TTC17,SNCB,KDM4B,FNBP1,KDM4C,ARHGAP26,TAB2,MAPK8IP3,SUPT5H,VAMP1,TGFBR3,PIK3R5,VAV2" Coexpression M7728 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 8.72E-07 1.01E-02 3.73E-05 3.71E-04 49 159 "RNF157,MIER1,ARNTL,B3GALT2,BACH1,CBFA2T2,EVI5L,PPT2,CSNK1E,PPP1R16B,HDAC9,DGKG,DNAJC6,MBNL2,PAN3,SEC24B,SEMA4D,CAB39,ARPP21,GRIK2,BACH2,HSF2,ITGAV,KCNH2,LIG4,XRRA1,NTRK3,PFKFB3,STRN3,PRODH,TTC13,RALGDS,FAM161B,WLS,MAGI3,ANKRD6,BTBD7,MAPKBP1,SMOC1,VAMP1,SLC37A2,TACC1,TCF12,GZF1,PRRT1,SLC38A1,NAV2,PARP11,NHSL1" Coexpression M7992 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout treated with rosiglitazone [PubChem=77999]: control versus IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "ADORA3,ZNF608,MAP4K3,ALS2,CADPS,STX16,BCL2L2,CNOT8,CLCN4,NIPBL,FAM171B,ARHGEF4,GIT2,SIRPA,ZC3H11A,RASA4,BSCL2,TLR7,PRKAG2,FOXO3,TMEM8B,INPP5K,SPIN1,STARD3,TPPP,NR3C1,HPS5,PADI2,DIPK1A,MATN2,MBNL1,LDLRAD3,RTL5,P2RY13,PIK3CD,PTK2,FAM120C,TMEM231,PLEKHB2,BSDC1,PCMTD2,AMBRA1,RCOR3,ZSWIM8,ERBIN,VAMP1,TCF12,WASHC4,ATP13A2,LMF1,P2RY12,WRN,WNK1,LMAN2L,SIGLEC10,RGS7BP,DOCK8,VANGL2" Coexpression M9289 Genes up-regulated in CD11c+ monocytes: control versus HAdv5 infection. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "AS3MT,SPARCL1,LTBP4,ATP1A3,ADAM15,CDK5R1,ST3GAL5,DIRAS1,SLC5A11,CD81,ARHGAP33,CDH18,DLGAP2,CHRM1,CHRNB2,FAM149A,CALY,SPOCK2,SRGAP3,DLG3,OLIG1,EBI3,TMEM35A,KATNAL1,SLC9B2,GAD2,ARFIP1,BRD8,GRIK4,CELF3,IGSF21,TOX2,CHST6,BCO1,P2RY13,TREM2,PLCD1,PLXNB1,POU3F2,LRRN3,PID1,CCDC25,SYNDIG1,HUNK,RYR1,MAPK12,DRAXIN,SCN8A,TET1,PALLD,SCN3B,FAM168A,FGD4,SYN1,BEX4,PARD3,TRH,TTC3" Coexpression M9352 Genes down-regulated in follicular B lymphocytes versus marginal zone B cells. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "LRCH2,APAF1,CACHD1,NCOA1,ATP1A3,ATP2B2,ATP6V0A1,SYNJ2,IL33,CA12,CALB1,CCKBR,VAX2,LY86,TOGARAM2,KIF26A,BLOC1S6,AK5,DYNC1I1,EDNRB,PHF20L1,EN2,MED12L,OLFM1,FGFR3,MEX3B,KHDRBS3,CGREF1,GABRG1,SRRM4,NEU3,GFRA1,DCLK2,GRID1,ATOH8,GPR45,SCIN,MEIS2,MID1,RCOR2,PFKP,PCDH18,IRX1,SLC22A23,RIT2,ROBO2,SH3GL3,NTNG1,FBXO11,LIMS2,SSTR2,SYT4,SIK3,XPO1,ANKS1B,LRP8,AMN1,ST8SIA2" Coexpression M8426 Genes up-regulated in pre-B cells: STAT5 knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "GRAMD1B,PLA2G4C,ASCL1,DNAH17,ATP2B2,ATP6V1G2,BMP7,CACNA1D,KALRN,CAMK2G,SCARB1,DLGAP2,CHGA,MAP4K4,CREB5,PDE4DIP,CNTNAP2,SLITRK5,CTNND1,RIMS3,USH1C,IGSF6,ADGRV1,C1orf61,AKAP3,B4GALNT1,GPR12,STON1,GRM3,PADI2,HPCA,HTR2A,IGSF1,KCNN1,KCNN3,L1CAM,LMO2,SMAD9,MX1,MYBPC1,MYH3,NPTX1,NTRK3,P2RX7,PBX1,PCSK2,CDK18,PGAM2,POU3F4,PTPRZ1,ZNF821,MCF2L,DOCK9,CRTC1,RIMBP2,PARD3,CAMK1G,ZNF248" Coexpression M6395 Genes up-regulated in plasma cells versus memory B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "CSMD3,FGD2,IGDCC4,BARD1,SYT6,SLC25A27,CSF3R,VCAN,TOMM20,CHRDL1,CELSR3,SRPK3,KCNMB2,ETV1,FCGR3A,ILDR2,ADAM28,FERMT2,CNDP1,GPR26,GRIA2,GRM5,IL1RAPL1,HTR5A,IL12A,CPNE9,BCO1,NDP,NEUROD1,NOS1,PAH,PCSK5,PDE3A,GPR173,NLGN3,MAPK4,MDGA2,RDX,SCN8A,PRCD,INAVA,SNRPN,SOX5,SPP1,IQSEC2,LRRC4,ELOVL4,FBXW11,USP1,ETNPPL,KCNT2,MKRN3,PLPPR5,STOX2,PCDH15,KCNAB1,PLD4,PLSCR4" Coexpression M9335 Genes down-regulated in follicular B cells versus those stimulated with anti-IgM and CD40 [GeneID=958] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 8.74E-07 1.01E-02 3.73E-05 3.71E-04 58 200 "ASPHD1,ATP2B2,MTMR9,GPR146,CACNG1,UBE2L6,MYL6B,AKAP12,IPCEF1,GPRASP1,ARHGAP32,HDAC4,EARS2,ZNF804A,FBXL5,RPS6KL1,CDON,ATN1,ST8SIA3,TSPAN5,CDKL3,TLR7,CHST15,SLC9B2,FGF13,SPECC1,HVCN1,GABBR1,GABRA4,INPP5K,IL6R,SYTL4,CD200,TMIE,LRP12,SLC26A11,SIDT1,RGS12,RNASEL,KIAA0895L,WLS,GALNT10,ZNF365,SLC15A2,ATF7IP,IZUMO4,MYCBP2,TROVE2,STX1A,MLC1,TCF7,ARHGEF12,TNS1,STXBP4,SSBP2,PMEPA1,LMAN2L,PPP1R3F" Coexpression M16909 Genes up-regulated in HepaRG cells (liver cancer) expressing constituvely active form of MTOR [GeneID=2475]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.05E-07 1.05E-02 3.85E-05 3.82E-04 131 566 "RBM10,ADCY8,AP2A2,C1QTNF1,ALAD,SRPX,LTBP4,BIN1,DDO,MADD,ARRB1,ALDH4A1,SLC4A4,ALDH7A1,MPDZ,BCHE,GYG2,CAST,SPAG9,AIFM1,CD86,CDO1,RCBTB2,CP,CHD1L,PDE4DIP,CTH,CTNND1,TM9SF4,GIT2,DBT,FAM13A,IRAK4,MFSD10,GPHN,EZH1,FCGRT,PRKAG2,C1orf61,IP6K2,IQCG,EVL,CINP,GPR153,OGA,AHCYL1,TMEM8B,CYP46A1,GNAS,PRRC2B,GSTT2,PSIP1,KLF12,HMGCL,IDH3B,IFI16,IGFBP1,ITGA7,JAK2,KCNK1,LAMA2,MT3,LYRM9,NASP,SLC11A2,NRDC,PCDH9,CDK18,PDE4A,C11orf49,SEPT4,POLG,PPARA,PPP3CA,CNNM2,SAMD9,BCAS3,VPS13C,FAM120C,PEX5,RAB5B,USP47,ZCWPW1,OXR1,RDX,RIC8B,RTN1,DGLUCY,ATXN1,COPZ1,SHMT2,AMBRA1,ST6GAL1,CLSTN1,DHX30,SLC6A8,RAB3GAP1,CDK5RAP3,ATF7IP,SLIT1,INTS9,IFT122,KDM4B,ARHGAP26,LHPP,ST5,APOM,DIP2A,SUPT5H,SYNE2,PLCB1,SYT1,IQCE,TCF4,SYNE1,DOCK9,NSD1,TF,ZNF34,KCTD2,KAT6B,CABIN1,TRPM2,ZMYND8,TSC2,ZKSCAN5,FLRT1,ZNF142,ZNF154,HPS4,KAT6A" Coexpression 12037678-Table2 Human Brain_Mukasa02_24genes GeneSigDB 9.13E-07 1.06E-02 3.87E-05 3.84E-04 14 23 "KALRN,INA,MICAL2,OLFM1,GRM5,PTPRN,RGS7,SLC1A2,RPH3A,SNAP25,SNCB,MYT1L,SCG2,KCNAB1" Coexpression M1713 Genes enriched in astrocytes in the adult mouse brain identified through correlation-based searches seeded with the astrocyte cell-type specific gene expression patterns. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.68E-07 1.12E-02 4.07E-05 4.05E-04 20 42 "SPARCL1,AQP4,ATP1A2,MAGI1,GPR37L1,CLU,NCAN,CST3,DBI,EMX2,GFAP,GLDC,GLUL,GSN,ITGAM,SEPT4,SOX8,BCAN,DIP2A,HEPACAM" Coexpression 20179214-Table2 Human Brain_DePreter10_42genes GeneSigDB 9.68E-07 1.12E-02 4.07E-05 4.05E-04 20 42 "ARHGEF7,MAP7,NCAN,EPHA5,FYN,INPP1,MAPT,MYCN,NRCAM,PMP22,PRKACB,PRKCZ,PTN,PTPRN2,CLSTN1,EPN2,CAMTA2,EPB41L3,CADM1,SCG2" Coexpression M17454 Genes up-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.05E-06 1.21E-02 4.38E-05 4.35E-04 133 578 "SLC12A5,NLGN4X,MTA3,MTUS1,ALAD,ALCAM,ANK3,ANXA7,BCAS1,CDC14B,SFMBT2,PDXK,ARNTL,ARRB1,ASPH,NCOA1,RASL11B,ATP2B1,DOCK11,SYNJ1,PRMT9,DDR1,CAMK2G,CAST,CBR1,CCPG1,CFL2,B4GALT6,CLCN3,TJP2,QKI,FAM149A,FAM171B,CRYM,CSNK1E,CTNND1,KIAA0513,MFAP3L,WDR20,SEC16A,DLX1,RCAN1,ABCC5,GOLT1B,EBF1,EDN1,FAM13A,VPS13B,EPB41L2,ERBB2,ERBB4,DENND4A,SRARP,FAM198B,RPS6KC1,ATP8A1,TOMM40L,FECH,FGF13,BAIAP2,SCARA3,JKAMP,TACC2,FUT9,GAB1,CAB39,NCKAP1,IQGAP2,TMEM8B,RND1,FERMT2,LNX1,DIDO1,GRIN2D,ZHX1,KLF12,ICA1,USP54,INPP1,DIPK1A,KCNMA1,MARK1,MATN3,PPM1L,IDNK,NFIA,NFIX,NPR2,SLC11A2,NUCB2,ZNF827,PBX1,PDE4D,PDGFRA,PDPK1,SMIM7,PMP22,PSAT1,SCHIP1,EPB41L4B,PACSIN1,PKIA,PRODH,PTPN13,RIPOR1,C12orf49,WLS,DGLUCY,GALNT10,SHANK2,SLC12A2,LIMCH1,PDZD2,RAP1GAP2,KANK1,KLHL7,C3orf70,TACC1,WWC1,IQCE,AKTIP,THBS4,BEX4,RPRM,TBC1D15,RICTOR,ZNF70,PRTFDC1,RNF103,FAM219B,TRAM2-AS1,GAN,SPATA13" Coexpression M10605 Genes down-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-06 1.24E-02 4.46E-05 4.43E-04 51 169 "ACTN1,KIDINS220,CACHD1,DACT3,NCOA1,CD81,CTNND2,CX3CR1,BOC,CNIH3,RCAN1,EDNRA,ATL1,EFNA3,ERBB4,SPEG,EXTL2,KATNAL1,MRVI1,DLC1,PPP1R1B,FHL1,FLNC,COPS8,FERMT2,LAMA2,MDFI,NPR2,DDR2,PCDH18,CEP41,MAPK7,PTPRZ1,RGS4,MAGI3,SLC4A3,SMTN,LIMS2,SNRPN,ZCCHC24,ZBTB43,MPRIP,OBSL1,THBS4,TPM2,TTC3,CADM1,VSNL1,NAV3,RTN4,MSRB3" Coexpression M2616 Genes transiently induced only by the second pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.08E-06 1.25E-02 4.50E-05 4.47E-04 338 1723 "KCNH8,ACHE,CLK4,EMILIN3,DSCAML1,TMCC3,ADORA2A,KIAA1211,ADRA1D,ADRA1B,LRFN2,GPR158,CASKIN1,USP35,PCDH10,UNC79,GPRASP2,PDZD4,DPP10,ANK1,PI16,DGKZ,KIAA1614,ZFYVE28,PLA2G4C,LINC00173,ASCL1,STK33,CAPRIN2,BRINP2,DDX3Y,DYNLL1,CCDC181,ATP2B1,ATP2B3,BCHE,RGS11,RGS9,BCL2L2,FGF17,OSGIN2,CDK5R2,CACNA1A,CACNA2D1,CACNG1,THSD7A,DIRAS1,KALRN,CAMK2B,VSTM2A,CBLN1,CBS,SHISA7,CCKBR,CDH8,LRRFIP1,NOG,CBARP,MS4A7,SYNPR,NRXN1,NGEF,VAX2,DNAJB5,CNR1,COL9A2,SLC4A7,RCHY1,IFFO1,MYRIP,HS3ST5,CSF1R,RGS6,CSF2RA,MICAL2,ATRNL1,PPP1R16B,CMTM5,SEC14L5,RIPOR2,FRMPD4,LONRF1,KCTD8,PHYHIP,BRINP1,ZNF804A,DGCR5,TIAM2,MAGI2,TMEM130,ALKBH8,SACS,NTM,FAM57B,DUSP9,EBF1,TSPAN5,EDN3,PHC2,SYT15,EFNA2,EFNA3,GPR61,MRO,RASA4,TENM1,SRPK3,RCAN2,KCNMB2,ANKRD13B,EYA1,HSPA12B,TUBB4A,CORO2B,OLFM1,POLR1B,FGF11,ACTL6B,FHL1,SCARA3,FOXG1,AGAP2,ZMYND15,FLNC,ATP13A4,FLT1,SGIP1,EFCAB2,AKAP3,AK8,TPPP3,TBR1,DOT1L,BRSK1,PHYHIPL,GABRA1,GABRA3,GABRB3,FAM184B,JPH4,SALL3,IP6K3,TMEM8B,IGSF5,FAXC,GBX2,MALT1,GJB1,ZNF276,RND1,HPGDS,MAP7D2,LOXL3,LILRA2,GPR22,MCHR1,GPR26,GPER1,GRIA1,C1QL4,GRID1,GRIK2,SPACA9,GRIN2C,GRM8,MFSD2A,ZBTB45,LINGO1,FRMD5,TNFAIP8L3,INSYN1,BACH2,HAPLN2,ZNF491,HPCA,NEGR1,OPALIN,ATCAY,EID2B,IRF8,SHISAL1,NKD1,SCIN,SCRT2,ITGA7,KCNA6,KCNB1,KCNC1,KCNF1,KCNJ3,KCNJ9,KCNJ10,L1CAM,LAMA2,INSYN2,LMO2,ASPRV1,NAT8L,MAPT,CHST6,ADAM11,MDFI,IL17D,TM6SF1,COL28A1,SAMD5,MSI1,MSR1,DDX25,LAYN,NEUROD2,PCBP3,OCRL,KCNK10,SNTG1,PAK3,PAX6,PCDH9,PDE3B,PDE4A,GNG2,PGAM2,ABCB1,JAKMIP1,FXYD1,ASPDH,PURG,PDZRN4,PMP2,ING3,POU3F4,HYDIN,PROX1,SAMD9,ZIK1,TMEM145,RAB3A,SH3TC2,ATG16L1,FEZF2,TSPY26P,MORC4,UEVLD,SPIN3,GLDN,RIMKLA,PLPPR3,ST6GALNAC6,ZNF568,CSRNP3,SLC30A10,STUM,FRMPD1,SHC4,SLC1A2,RPH3A,PREX2,SLC2A5,FAM214B,SLC6A7,ZNF430,TRIM67,SLC12A4,EFHD1,SLCO1A2,NAXD,CXXC4,OGDHL,SORCS3,RIMS1,SNAP25,ANKFN1,FAIM2,ZNF415,UNC80,SOX3,SOX5,SOX15,NMNAT2,CAND2,BEX1,IQSEC2,SSTR2,EPB41L3,ELOVL4,STAC2,SEPT3,ZFR2,MCF2L,PDLIM2,ALG1,CNTN2,WSCD1,NEU4,ZEB1,PCDHB15,PCDHA2,TEX15,SIRT1,FBXL16,GALNT17,TLL2,TLR4,TNFRSF1B,PRRT1,TPD52L2,RASD2,IL34,TRPC3,NTSR2,ANO5,TUBB2A,HEPACAM,RPRM,OSBP2,TSPAN11,RBFOX3,CLIP2,ZNF781,KLC2,PORCN,ZNF711,ATP6V0E2,CRB2,MKRN3,CELF4,EML6,DPYSL5,ANKS1B,STOX2,GAL3ST3,SLC17A7,DNAH10,GJC2,ADAMTS10,SLC39A12,SSPN,DPF3" Coexpression M2581 Genes up-regulated in the HSC supportive stromal cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.10E-06 1.27E-02 4.56E-05 4.53E-04 78 297 "RALGAPA1,NCKAP5,NDRG2,GALNT13,RNF150,SORCS2,LRRC4C,ARRB1,SLC4A4,HCN2,THSD7A,UBE2L6,ARHGEF6,AKAP6,SDC3,PYGO1,RASSF2,RHOBTB1,CALCRL,MTSS1L,SPEG,FABP7,TVP23A,FYB1,B4GALNT1,KIRREL3,DCLK2,GNAO1,PRUNE2,LPAR4,GPER1,BACH2,ZDHHC15,IGF1,KCNA4,MATN2,MEST,KITLG,MN1,CCDC80,NRBP2,RSPO2,NCAM1,NOVA1,NPR2,CDK18,PDE1A,PDE4D,PDE1B,PDGFRA,PMP22,PRKAR1B,PTN,CASTOR1,PTX3,RAB3IL1,FAT4,OXR1,MORC4,RGS4,RORB,PEAR1,ST6GAL1,SLC1A3,SOX5,SPP1,SULF2,SYN1,ARC,SLC37A2,POPDC3,PCDHB15,TEX15,TMEM121,ITGB3BP,TMEFF2,PORCN,ELFN1" Coexpression M14594 Genes with copy number losses in primary neuroblastoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.12E-06 1.30E-02 4.64E-05 4.61E-04 174 799 "AS3MT,ARID1A,ADD3,TBC1D14,CC2D2A,AK2,GOLGA7B,USP28,KCNAB2,GPAM,MIER1,ARRB1,ATM,EIF4G3,ADGRB2,MTMR2,BTRC,CAMK2G,METTL6,INA,C1orf52,CDC42,ZMYM4,ZNF445,SRSF11,BTF3L4,COL9A2,SLC4A7,MYRIP,CRMP1,HINFP,TENM4,SEC24C,FEZ1,ATRNL1,CHD5,PUM1,EDRF1,ARHGAP32,TBC1D5,RIMS3,DNAJC6,HP1BP3,ALKBH8,CDON,CPEB2,PDCD6IP,PHC2,HEYL,SIDT2,SH3GLB1,PLEKHA1,ELAVL4,EPB41,MFSD10,SRRM1,CHST15,ZNF589,MAD2L2,FGR,HPCAL4,TMEM175,DPYSL4,ZCCHC17,SORBS1,GPR153,MSANTD4,CHL1,CPLX1,AHDC1,RAB30,ADGRA3,CROCCP2,GRIA4,GRID1,ATE1,TMEM25,ACOT7,HMGCL,RBPJ,DOCK7,JAK1,STMN1,HECTD2,FGFBP3,NAT8L,ZFYVE27,JAKMIP3,THYN1,NASP,NFIA,NRDC,NUMA1,OGG1,CYTL1,CCSER2,EXOSC10,SPATA6,PPP3CB,PRKACB,PRKCZ,QRICH1,PIGG,PTAFR,NKAIN1,BEND5,BSDC1,MSANTD2,RDX,ZYG11B,DPF2,RGS12,ARHGEF10L,TTLL7,RNF220,PBRM1,CCDC82,SETD5,ALG9,EPHA10,RPL15,SATB1,ATXN7,SCP2,FOXRED1,SFPQ,ASRGL1,SH3BP2,ASAP3,CPEB3,ST3GAL3,PAAF1,CLSTN1,DHX30,RUFY2,KDM4D,SCMH1,USP33,WDTC1,ZSWIM8,GLT8D1,EMC1,KIF1B,ZNF621,MIR100HG,PBLD,CLASP2,NCDN,NEK4,FAM168A,DNAJC9,ANKRD28,CAMTA1,TMEM136,TPCN2,SZT2,ARHGEF12,FRYL,SIK3,ATP13A2,SIRT1,MTMR14,TNFRSF1B,KAT6B,NR2C2,FNDC5,CADM1,MEAF6,NSD2,SYNC,EMSY,PRDM2,DNALI1,PRDM10" Coexpression 18032706-SuppTable3 Human Leukemia_Ruiz-Vela08_468genes GeneSigDB 1.13E-06 1.31E-02 4.65E-05 4.62E-04 96 387 "ACTN1,GALNT16,ADCYAP1R1,ADRB2,HACE1,KCNT1,ANK3,LCORL,APBA2,APOC1,APOC2,CPNE5,SPTBN4,CADPS,ASCL1,ASGR1,ATP6V0A1,ST3GAL5,C5,TIGD7,RCBTB2,CHGB,CHI3L2,RAB33A,FADS2,HOMER3,PICK1,LETMD1,COL9A3,ANKRD44,ATRNL1,PLCXD3,CTH,BOC,RIMS3,DBN1,GSDME,CD99L2,SHANK1,OPTN,LRRC23,APC2,REEP2,DLC1,ST3GAL6,SYNCRIP,TPK1,GAA,GAB1,HIGD1B,TDRKH,MIER3,HSP90AA1,DISP2,TUBB2B,ITGAM,LMO2,LSS,MAT2A,SYT9,EFHB,TM6SF1,MOBP,MX1,NELL1,NPTX1,GDAP1L1,JAKMIP1,POLR2F,TATDN3,PRODH,PTPRH,RFX3,CARF,TCP11L1,RPS6KA2,SAFB,FHOD3,GKAP1,NCDN,ARHGEF9,SIN3B,ZFP90,TCF7,DNAH7,FBXL16,TST,VLDLR,ZNF70,POLR3H,NT5M,RGMA,STMN4,MDH1B,CAB39L,PCBP4" Coexpression 18787207-TableS2 Mouse Viral_Craft08_969genes GeneSigDB 1.13E-06 1.31E-02 4.65E-05 4.62E-04 149 664 "RNF157,ADD3,AXIN2,GRAMD1B,NR0B1,TAOK1,SEMA6A,C1QTNF4,SPOP,FAM135A,LRFN1,EP400,APP,LGR5,CASK,MARCH3,PTCH2,NUMB,ADGRB2,RGS11,FUBP1,KALRN,PTBP2,CCNH,CACNA2D2,SRSF11,FOXN3,RAB28,PLAA,ARMC8,RCHY1,FAM171B,PNKD,SNCAIP,TENM4,MICAL2,CHD5,BOC,FGFR1OP2,TCAF1,HDAC4,RASSF2,MATR3,CTIF,DBT,ZEB2,B3GAT3,HP1BP3,TMCC2,DLG3,SLC29A4,DNM2,ARRDC4,DNAJB6,EBF1,FSD1L,EFNA2,SH3GLB1,PHF20L1,ELAVL3,PCOLCE2,STX2,EPS8,ERBB2,CDKL3,KATNAL1,FGR,ATP5PD,SYNCRIP,FLNC,FLT1,ATP2C1,DOT1L,RAPGEF6,SALL3,MTHFD2,AHDC1,TXNL4A,GNG3,CECR2,CIT,SOX21,CELF3,ATG4C,HMGB1,AGBL5,ZDHHC15,TUBB2B,LIMS1,ARHGAP12,CCDC80,NAP1L1,NEK1,CNOT4,PCBP3,OGG1,TREM2,PDPK1,PLEC,MED1,MAPK10,ANKHD1,RDX,RGS3,RPE,FBXW7,RXRA,FOXRED2,SALL1,MRAS,CHD9,PPP4R3A,CCDC88A,EPC1,FAM126B,SOX2,BDP1,SOX11,IZUMO4,UNC5B,BEX1,POGZ,ZC3H4,PRRC2C,SYN1,ARC,ATP11A,CAMTA1,SMG6,CLASP1,WDR7,PCDHA1,HIF3A,SIK3,PARD3,CABIN1,STXBP4,VAV2,RICTOR,ZIC2,SPIRE1,ZFAND5,WNK1,RTN4,HNRNPA3,PHTF2,ACTR3B,FXR1,AP3B2" Coexpression M8591 Genes up-regulated in cells sorted as ITGAX int [GeneID=3687]: EMR1 high [GeneID=2015] macrophages versus EMR1 int [GeneID=2015] dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 1.17E-06 1.35E-02 4.77E-05 4.74E-04 52 174 "SNX30,TBC1D14,ARRB1,MARCH3,ATP1A3,GPR146,KSR1,SYNJ2,BTRC,CAMK2G,SLC25A14,SH2B1,PDE4DIP,C2CD2L,DPYSL2,GNE,SNX29,LPAR6,PLEKHO1,EXTL2,PRMT5,BAIAP2,AGAP2,ANKFY1,TMEM175,INPP5K,MSL3,COQ10A,OPHN1,P2RX7,TREM2,PFKFB2,PMS2,ING3,RETREG2,CNNM2,TMEM104,ZDHHC14,UBR7,TMEM206,ADAL,RASA3,MBD5,TAL1,TIAM1,LRRC8A,KAT6B,CDK20,SH3GLB2,INTS3,TUBA1A,MVB12B" Coexpression 16488994-SuppTable1a Mouse Lung_Lu06_856genes_Array MG_U74Av2 GeneSigDB 1.23E-06 1.42E-02 4.99E-05 4.96E-04 108 449 "ADCY2,ADCY8,ADORA1,ADRB2,ALCAM,LTBP4,ANK1,PKP4,GPAM,ARRB1,NUMB,ATP1A2,MPDZ,PROM1,BTRC,CAMK2D,LRBA,ADGRG1,RAB28,PLAA,CLU,HOMER3,CNTN1,COL4A5,AKAP12,CSF1,CSNK1E,VCAN,CTNND1,SIRPA,EDN1,EGFR,SORBS3,RASGRP2,EFS,F5,FECH,FER,FGFR1,FHL1,FLT1,FYN,DKK3,GAB1,ZMYND11,GAP43,SESN1,GFRA1,GGT5,LYVE1,GJB1,CRCP,FERMT2,LNX1,PCLO,RAPGEF4,STMN2,GRIA1,GUCY1B1,HP,IGF1,IL6ST,ITGA7,ITPKB,KCNH2,KCNK2,KIT,LAMA2,STMN1,MBP,MITF,MYO6,MYO7A,NBL1,NRGN,DDR2,P2RY1,PALM,PCSK5,PDGFRA,GNG2,PLP1,PMP22,PPP2R5C,RELN,PTPRB,PTPRD,PTPRE,PTPRZ1,ROGDI,RASGRF2,DPF2,RGS4,RGS10,ROBO1,RPS6KA2,RTKN,MRAS,SPP1,TNS2,PCDHA1,TEK,ZMAT3,ZNF106,TIE1,TNFRSF1B,AMOT,SSPN" Coexpression M14228 Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.23E-06 1.42E-02 4.99E-05 4.96E-04 35 100 "AS3MT,ADD2,KIAA1211,RNF150,NLGN4X,GPR158,SYT13,LGR5,TMEM108,ADAM23,CLDN10,COL9A2,COL9A3,ARNT2,DLX1,DMD,PCOLCE2,OLFM1,MAP7D2,LIFR,LSAMP,CD200,MYCN,NPTX2,NRCAM,CLDN11,PENK,LAMA1,PTX3,ANKRD6,PEG10,SYNPO2,UCHL1,ZIC2,ZNF711" Coexpression 15902281-TableS1d Human Leukemia_Schoch05_1441genes GeneSigDB 1.24E-06 1.43E-02 5.00E-05 4.96E-04 134 585 "ACHE,ADCYAP1R1,FZD9,AMPH,CDK13,AZGP1,SGCE,CACNA2D1,THSD7A,CAMK2B,DGKI,AP4M1,SEPT7,TBRG4,ASIC3,CHN2,KMT2C,SUMF2,CREB5,OSBPL3,CNTNAP2,PHF14,FAM131B,DOCK4,HDAC9,TCAF1,INTS1,DGKB,SCRN1,KIAA0087,ELMO1,MAGI2,GSDME,POM121,CALN1,DYNC1I1,DMTF1,DPP6,DNAJB6,FIS1,SEMA3D,EGFR,RASA4,AASS,ELN,STARD3NL,EN2,LRRC17,MTSS1L,ETV1,ACTL6B,PRKAG2,FLNC,TPK1,MPP6,DENND2A,GCK,CRCP,DBF4,GPR22,GPER1,GPR37,PCLO,GRB10,GRM3,GRM8,HTR5A,ICA1,IGFBP1,SCIN,KCND2,KCNH2,MEST,MKLN1,ADAM22,ZNF862,NDUFA5,CNOT4,NPY,NPTX2,NRCAM,OGDH,PDE1C,GPR85,CDK14,PGAM2,ABCB1,PHKG1,ANLN,SNX10,ING3,PILRA,NXPH1,LRRN3,CEP41,PRKAR1B,RELN,SAMD9,PTN,PTPRN2,PTPRZ1,ZCWPW1,ZDHHC4,PPP1R9A,URGCP,SMARCD3,SP4,HECW1,PEG10,SRPK2,NACAD,STX1A,KLHL7,SYPL1,COBL,TAC1,TAF6,IQCE,AHCYL2,PMS2CL,GALNT17,RUNDC3B,ZKSCAN5,UBE2H,VGF,VIPR2,CLIP2,LAT2,ATP6V0E2,ZNF138,SLC30A3,ST7,PHTF2,ACTR3B" Coexpression 15869706-Table3 Human Cervical_Rosty05_51genes GeneSigDB 1.25E-06 1.44E-02 5.02E-05 4.99E-04 21 46 "PPFIA4,DDO,CACNB2,CAMK2B,ST18,NRN1,FGFR3,GNAO1,GRIK4,NEFH,SLC6A15,ANKRD6,SLC4A3,SLC6A8,SMARCA4,OGDHL,ADGRL3,TRIM2,KCNE5,ZXDA,CAMK1G" Coexpression M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.32E-06 1.53E-02 5.31E-05 5.27E-04 110 460 "CPNE2,ACTN1,FMNL2,ADD3,SRPX,BIN1,RGS20,ATM,RNF182,BACH1,BCHE,MTMR2,SPAG9,CDC27,CFL2,SLIT2,NMT2,QKI,MAP4K4,CNRIP1,NECTIN3,AKAP12,FEZ2,TOX,CEP170,GSDME,SACS,SV2A,AK5,DMD,DNM1,EDIL3,SH3GLB1,EGFR,EPB41L2,STX2,EXTL2,KATNAL1,CORO2B,FER,FHL1,FOXF2,FLNC,PNMA2,DKK3,MALT1,GLS,NR3C1,HAS2,TOX2,IGFBPL1,IFI16,INPP1,DIPK1A,ITGAV,IPO5,SMAD9,MID1,LAYN,PDE4A,GNG2,PFKP,SERPINE2,ANLN,PIK3CD,PMP22,SH3KBP1,SPDL1,PTPRG,PTX3,FAT4,ZYG11B,RGS4,CCDC82,KIRREL1,WLS,SFPQ,SGK1,ITSN1,DOCK10,FHOD3,DZIP1,ARHGEF40,CCDC88A,ZCCHC24,NMNAT2,MIR100HG,ITPRID2,MPRIP,ANKRD28,POPDC3,MTCL1,NR2F1-AS1,EHBP1,ZEB1,WASHC4,FAM200B,GPR161,TPM1,ELP5,TRIO,FLRT2,WIPF1,CLIP2,ZIC2,DHX33,NAV3,ITM2C,RTN4,MSRB3" Coexpression M6315 Cluster 2: genes down-regulated in lung tissue samples from mice with oncogenic form of KRAS [GeneID=3845] and inactivated PTEN [GeneID=5728]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.33E-06 1.54E-02 5.33E-05 5.29E-04 89 353 "DPF1,ADCY8,GALNT13,SPARCL1,ABCD2,TMEM263,MPDZ,CACNA1A,MAP7,LDB2,METTL6,ARHGEF2,DCLK1,NDST3,TMEM184B,AKAP12,PDE4DIP,ARHGEF4,ST18,EARS2,TMEM170A,CTIF,ELMSAN1,SV2B,CDON,DYRK1A,EBF1,TMTC1,EIF4G2,CALCRL,RASGRP2,NCALD,CACNG2,FGF14,FHL1,FOXF2,ATP13A4,GPR153,ST6GALNAC3,GNAS,GPD2,GRM5,GSN,MAN1B1,TLX1,SHISA6,IRF8,KCNMA1,MAP2,MAP4,MEIS2,KITLG,MYO5A,MYT1,ENPP2,PFKFB3,ABCB1,PLTP,PMP22,FA2H,IRX1,PTPRD,NKAIN1,SUSD4,ZMAT4,ZFHX4,CLIP1,SATB1,SELL,SFPQ,EPN2,INTS9,PDZD2,MYT1L,ZSWIM8,DDN,SPART,SYN2,DDHD2,FBXW11,TEK,ITGB3BP,TPM1,RGMB,CLEC2L,RICTOR,ZBTB14,AMZ1,LRP8" Coexpression 18308945-Table4 Human StemCell_Huang08_120genes GeneSigDB 1.37E-06 1.58E-02 5.45E-05 5.42E-04 38 113 "PKP4,GPAM,DPY19L3,SPAG9,ZMYM4,CLGN,SV2A,ELN,EFCAB2,ATP2C1,ZNF605,GOLGB1,ADGRA3,RBPJ,MEIS1,MEST,CD200,NAP1L3,NEK1,PBX1,PDE1A,EPDR1,RBBP8,ROBO1,BAALC,CHD9,ZNF334,ZNF667,BEX1,EHBP1,OBSL1,TMEM9,TP53BP1,TRO,NSD2,MICU3,ZNF70,GOPC" Coexpression M11749 "Genes up-regulated in SCLC (small cell lung cancer) cells with acquired resistance to ABT-737 [PubChem=11228183], an inhibitor of the BCL2 [GeneID=596] family proteins." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.37E-06 1.59E-02 5.45E-05 5.42E-04 18 36 "KCNT1,BRSK2,CD81,EEF1A2,ELAVL3,OLFM1,FLNC,NSG1,PNMA2,PCSK1N,STMN2,HBA1,NPTX2,GNG2,PPP2R2C,RTN1,SST,ITM2C" Coexpression M15103 "Genes up-regulated in A4573 cells (Ewing's sarcoma, ESFT) after knockdown of BMI1 [GeneID=648] by RNAi." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.38E-06 1.60E-02 5.48E-05 5.44E-04 130 565 "ASIC1,ADCYAP1R1,USP31,FAM135A,CNIH2,SUGT1P4-STRA6LP-CCDC180,APLP1,CACHD1,LGR5,IGDCC4,TMEFF1,ADGRB2,BMP7,CACNA1G,OSGIN2,WASF1,PRC1,INA,SCARB1,KCNAB3,NOG,TAOK2,ZFYVE9,QKI,TMEM184B,RAB26,BAG4,CRMP1,NCOR2,CRYM,CS,CNTNAP2,KIAA0408,BOC,CCDC3,DLG4,SLC29A4,CDON,SHANK1,EDIL3,HIPK3,AASS,CERCAM,ELN,LRRC17,STX2,CD320,TBC1D16,TUBB4A,PRMT5,SEC24B,OLFM1,FGF13,AGAP3,NPTN,B3GAT1,TPPP3,DKK3,DNER,GPR162,GFRA1,C1QL1,TNRC6A,PRRC2B,DIDO1,ATE1,GSN,PTPN5,MFSD2A,FAAP20,IDH3A,RBPJ,IL6ST,IL11RA,TUBB2B,ITPKA,CYP27C1,ZNF92,NDUFA5,NELL2,NFYA,NKX2-2,PDE4A,PDE1B,CDK14,DUSP26,CAMKV,KCTD15,PLTP,MBOAT7,FSD1,PPP1R1A,PKIA,MAPK3,RALGDS,RDX,RGS4,C12orf49,TMEM206,BAALC,HUNK,SLC1A3,URGCP,EFHD1,PEG10,SS18,MPRIP,TEX15,VWCE,GALNT17,TPM1,TPM2,NEIL2,RUSC1,TUB,TUBB2A,UBTF,PLPPR2,CLDND1,ZIC2,FTSJ1,MAP3K12,LRP8,PRDM8,SLC17A7,SNX27,TMEM163,PCBP4,ZDHHC20,SOCS4" Coexpression M17843 Top 20 positive significant genes associated with schwannoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.40E-06 1.62E-02 5.52E-05 5.48E-04 12 18 "ADORA3,NLGN4X,APOC2,PLEKHB1,NRXN3,NRXN1,GFAP,L1CAM,TREM2,PLP1,S100B,SEMA3B" Coexpression M6689 Genes down-regulated in fibroblasts: untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.41E-06 1.64E-02 5.56E-05 5.52E-04 52 175 "OGT,LCORL,SFMBT2,ARHGAP5,ARNTL,ARRB1,DPY19L3,DST,VAX2,LRIG1,USP6NL,DGKG,KLHL3,NR1D2,FSD1L,LPAR6,PAN3,GTF2IRD2,ST6GALNAC3,GABBR1,GGT5,MALT1,TDRKH,KIF5C,MITF,MYO9A,NTRK3,PDE3B,ZDHHC8,SMOX,PRKCB,VPS13C,EML5,PTPRZ1,RGS10,RPRD1A,TCP11L1,SATB1,SCP2,ST8SIA1,RAB3GAP1,KIF13A,ZHX3,TEX2,KIF1B,ACSBG1,CAMSAP2,ARHGEF12,R3HDM1,KAT6B,CLIP2,PPP1R3F" Coexpression M3062 The 'group 2 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 and ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.42E-06 1.64E-02 5.56E-05 5.53E-04 112 471 "ABHD6,PSMG3-AS1,NME5,CC2D2A,SPOP,KIF6,API5,SHROOM2,RNF182,ZNF599,CDK5R1,CASTOR3,JAZF1,SLC25A14,LOC730101,LRWD1,LHX2,NGEF,HECTD1,IQCK,FAM149A,SLC4A8,TOGARAM2,ARHGEF4,GAPVD1,DNAL1,SRGAP3,WDPCP,FSD1L,PLXNC1,EML1,LRRC23,RAB9B,CDKL3,DNAJC27,CEP78,ZMYND10,CAMSAP1,SCARA3,IQCG,DCTN2,EFCAB2,POMT1,AK8,TPPP3,ABLIM2,KIAA1841,MSL3,GPM6B,CNTRL,SPACA9,KIF3A,FAM19A2,LINGO1,PSIP1,CFAP126,HSP90AA1,C1orf194,MAP6,EFHB,WDR49,DDX25,NPTX2,ODF2,DPY19L2P2,SPATA6,CEP41,LRRC49,UHRF1BP1,TMEM231,CCDC40,REV3L,RFX2,RFX3,SEC61A2,NEK11,MELTF-AS1,RMI1,HES6,PPM1E,DZIP1,RADIL,SHANK2,IFT122,CABCOCO1,TMCC1,ZHX3,CLUAP1,ENKUR,STOX1,NEK4,TCF7,RPGRIP1L,AKNA,CCDC173,DNAH7,TMEM121,NACC2,CDK20,ZNF346,PPIL6,TUB,CLHC1,FAM181B,CFAP298,CFAP52,REEP1,EML6,DNALI1,MDH1B,ST7,NETO2" Coexpression M2783 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of PCGF2 [Gene ID=7703] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.43E-06 1.65E-02 5.59E-05 5.55E-04 46 148 "ASIC2,NDRG2,GAS7,PROM1,MAP7,SLC16A4,CDH10,UBE2L6,CHN2,COL9A3,TCEAL2,CREM,CLIP3,SNCAIP,TCAF1,DMD,EEF1A2,PDLIM5,B3GAT1,SYT17,PPARGC1A,STON1,KCNJ16,MAOB,GPR88,PCDH8,PDE4B,PENK,SERPINI1,PID1,C1orf54,PNMA8A,BAALC,KANSL3,EFHD1,SOX2,ZCCHC24,DOK5,NMNAT2,EPB41L3,PLCB1,CUX2,TRIM2,CDH22,TMOD1,SLC17A6" Coexpression M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-06 1.67E-02 5.62E-05 5.58E-04 105 435 "NDRG2,ADCY8,ADRB2,SPARCL1,LTBP4,SEMA7A,GPAM,PRX,TMEFF1,ARRB1,NUMB,ATP1A2,ATP2A2,ALDH7A1,MPDZ,PROM1,CACNB2,KALRN,CDO1,RAB28,QKI,CNTN1,CP,AKAP12,FEZ2,RIPOR2,SPOCK2,ARMCX2,HEPH,DNM1,EDN1,EDNRB,PLEKHA1,CALCRL,EPB41,EPB41L2,MTSS1L,EPHA5,FHL1,FOXF2,FLT1,SORBS1,FYN,ZMYND11,SESN1,GFRA2,LYVE1,GLUL,FERMT2,GPM6B,STMN2,GSN,PSIP1,GUCY1B1,GYG1,HP,IL6ST,ITPKB,KIT,LAMA2,LIFR,LMO2,MAP4,MAPT,MATN2,MEF2C,MEIS1,KITLG,MYH6,MYL3,MYO6,PDGFRA,ENPP2,GNG2,CDK14,FXYD1,PLTP,PMP22,SEPT4,PKIA,PTCH1,PTPRB,PTPRD,ROBO1,SATB1,SCN7A,TNFRSF19,LIMCH1,SNCA,SOX2,SOX11,SPTAN1,ST5,TCF4,TNS2,TEK,TIAM1,TIE1,HEY1,TJP1,CADM1,ZBTB16,WNK1,TUBA1A,SSPN" Coexpression M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.47E-06 1.70E-02 5.69E-05 5.65E-04 70 260 "SERPINA3,SRPX,OGT,ANK2,GAS7,ASPA,ATP1A2,SGCE,DCLK1,CDO1,SLIT2,ABI3BP,FEZ1,SUSD5,VCAN,PDE4DIP,HDAC4,SCRN1,CHRDL1,ECM2,EGFR,TENM1,PCOLCE2,LRRC17,EFS,F3,ABCA8,EFEMP1,SCARA3,CHL1,GSN,GSTM5,HNMT,IGF1,DIPK1A,KCND2,KCNK1,LAMA2,MBP,LRP1B,MEIS1,MEIS2,MEST,MITF,NOVA1,NTRK2,DDR2,PCDH9,PDGFRA,SERPINE2,FXYD1,PLP1,PLTP,PRRX1,ELOVL2,PTPN13,PTPRD,PTPRG,PTX3,PID1,RERGL,ROBO1,ATP8B4,MEG3,DZIP1,PEG10,KIAA0930,TRO,FLRT2,SSPN" Coexpression M8189 Genes down-regulated in double positive thymocytes from OT-2 transgenic mice: control versus injected with agonist peptide. MSigDB C7: Immunologic Signatures (v6.0) 1.53E-06 1.77E-02 5.92E-05 5.88E-04 53 180 "ARID1A,ADD1,ADD3,ALCAM,DGKD,NCOA1,ATP6V0A1,DOCK11,AP1M1,CACNA1I,MAP4K4,ANKRD44,CSNK1G3,MYADM,RIPOR2,SNX29,FRY,PLEKHO1,RASGRP2,PTK2B,CHST15,SPSB4,GABRA2,RAPGEF6,DCLK2,ADAMTS6,BACH2,JAK1,LMO2,MEF2C,CD200,PDE2A,LRP12,PPP3CA,PXK,SATB1,SELL,RASA3,SGK1,SH3BP2,ST6GAL1,SMARCC2,LMBRD1,TNIK,KIF21B,CDK19,DNAJC9,PSD3,AKNA,SSBP2,RICTOR,TUBA1A,SSPN" Coexpression M10117 Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [GeneID=4869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.57E-06 1.82E-02 6.04E-05 6.00E-04 67 246 "TKTL1,APP,PROM1,WASF1,BAIAP3,LDLRAD4,THSD7A,RUNX1T1,CD38,CACNA2D2,B4GALT6,NRXN2,C2CD2,CLIP3,CSF3R,PPP1R16B,ST18,TOX,SCRN1,DPYSL2,OPTN,LPAR6,EPS8,FGF13,FGFR1,FHL1,EVL,GALC,GATM,HPGDS,GPM6B,GSN,IFI16,KIT,TM6SF1,MEF2C,MEST,MN1,CD200,MX1,NBL1,NCAM1,PALM,PDE3B,PDE4B,CYTL1,ABCB1,SERPINE2,GPSM2,PRODH,SIDT1,ROBO1,BAALC,RPS6KA2,STK32B,MEG3,SNCA,AGTPBP1,ARHGEF12,TMOD1,TRH,KCNE5,SSBP2,VLDLR,LAMP5,SLC38A1,ITM2C" Coexpression 18223198-Table3 Human Brain_Chen-Plotkin08_40genes_FTLD-U GeneSigDB 1.58E-06 1.83E-02 6.04E-05 6.00E-04 17 33 "DLGAP2,COL4A5,HS3ST2,ECM2,EGR3,NRN1,ABCA8,GFRA2,GRM7,HTR2A,NPTX2,PAK3,PTPRN,SLC14A1,ARC,SYT5,VGF" Coexpression 18223198-Table5 Human Brain_Chen-Plotkin08_40genes_GRN+ FTLD-U GeneSigDB 1.58E-06 1.83E-02 6.04E-05 6.00E-04 17 33 "ATP1A3,CDC42,ECM2,EGR3,ABCA8,GABRA1,ARPP21,STMN2,LAMP2,PCDH8,PCSK1,RGS4,SCN3B,SYT1,TAC1,ZIC1,SCG2" Coexpression M6652 Genes down-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL6 [GeneID=3469] and LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.67E-06 1.93E-02 6.31E-05 6.27E-04 57 199 "ADORA3,ABCD2,PITPNM2,ATP1A2,FGF17,CA12,RHBDL1,LONRF2,KCNAB3,HECTD1,NIPBL,ARHGEF10,COPS7A,PLPPR4,TRAPPC9,DNM2,SLC25A18,ST8SIA3,IRAK4,VPS26C,EFCAB2,NSG2,STAG2,ATP8A2,PCDH17,HPGDS,GLDC,TNRC6A,ZHX1,FRMD5,FRMD3,HLF,KCNN1,KCNQ3,CHST6,NEUROD1,PPP2R2B,KANSL1,TMEM104,PID1,LIMS2,WDR47,SPTB,FAM168A,MLC1,SLC37A2,TBL1X,TIE1,WBP2,OSBP2,KCNK12,XRCC4,EMX2OS,SNX27,WIPF2,CBLN2,SENP7" Coexpression M8361 Genes up-regulated in T reg: natural versus induced cells. MSigDB C7: Immunologic Signatures (v6.0) 1.67E-06 1.93E-02 6.31E-05 6.27E-04 57 199 "ADORA1,SEMA6A,SRPX,ANK1,AQP6,BRINP2,EIF4G3,ATP6V1G2,ADGRB3,BTK,SCAPER,CAMK2A,ENTPD2,CLGN,COL9A2,AATK,SDC3,PHYHIP,DGCR5,DLG2,DTNA,EPB41L1,ERBB2,ERBB4,EXTL2,CAP2,GABRB3,RAB30,GLRB,TOX3,PRUNE2,GRM8,HPCA,IGFBP1,KCNH1,MN1,PCSK5,SCHIP1,CNNM2,PTPRD,PTPRZ1,EXD2,PPM1E,SLC6A1,SLC22A4,PDZD2,CDK19,DMXL2,PCDHA3,LEFTY2,THRA,SEZ6L,TTPA,FAM155A,FLRT2,ZIC3,AP3B2" Coexpression M3104 Genes up-regulated in comparison of naive T cells versus effector memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.67E-06 1.93E-02 6.31E-05 6.27E-04 57 199 "ACTN1,ELFN2,KLHL13,PITPNM2,APBA2,SFMBT2,ATM,DDR1,KYAT1,SCARB1,NOG,CHI3L2,IPCEF1,GPRASP1,SNPH,ARMCX2,KLHL3,AK5,CCDC3,KBTBD11,SLC12A6,SCML2,FCGRT,NBEA,RAPGEF6,GGT7,ADGRA3,ZNF496,LINC01089,LINC01550,BACH2,IL6ST,KPNA5,DNHD1,NUCB2,PCSK5,PDE3B,PIK3CD,LRRN3,CEP41,TUG1,BEND5,GAL3ST4,RGS10,SATB1,CNKSR2,RAB3GAP1,ROBO3,TBL1X,TCF7,PRRT1,TOM1L2,ZNF708,ZNF138,AMN1,CERS6,KLHDC1" Coexpression M4526 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.67E-06 1.93E-02 6.31E-05 6.27E-04 57 199 "NDRG2,AP2A2,BIN1,AMT,DGKD,APP,ATP1A1,STX16,ST3GAL5,CFAP410,CAPN3,P2RX6,ARHGEF1,CDC25B,NPIPA1,COX4I1,SH2B1,SNPH,INTS1,SGSM2,DMTF1,SORBS3,ATP8A1,KAT8,IP6K2,ARFGAP2,ERGIC3,SARAF,OGA,TMEM8B,USP19,RAB40B,MSL1,IL11RA,ITPKB,KCND1,KIT,MN1,NAP1L1,CAMKV,PRKCZ,SNRK,RGS12,R3HDM2,RCOR3,TTC17,FAIM2,MYCBP2,TSPYL2,ERBIN,CEP68,MCF2L,KAT6B,TTC3,SF1,PARP6,KAT6A" Coexpression M2494 Genes down-regulated in primary LEC cells (lymphatic endothelum) upon overexpression of MIR31 [GeneID=407035]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.72E-06 1.99E-02 6.48E-05 6.43E-04 101 416 "SLC44A5,OSBPL6,TRMT9B,RGS20,PLA2G4C,N4BP2L1,MYOM1,SNAI3-AS1,LDLRAD4,CA4,CACNB2,LDB2,CLGN,SOCS6,PLEKHB1,CLU,ABCG2,ANKRD35,CREM,AKAP12,CSF3R,KIAA0040,NOS1AP,RASSF2,SPOCK2,AIF1L,SV2B,EBF1,EDNRB,DCTN4,VPS13B,RCSD1,HSPA12B,GTF2IRD2,FGF12,ZMAT1,GAD2,DISC1,CYP46A1,LYVE1,GLRB,KCNMB4,PCLO,STMN2,BVES,GUCY1A1,RBPJ,ZNF678,LAMA2,SMAD1,AFDN,MMP16,MX1,NCF2,IDNK,NRCAM,P2RX7,SERPINE2,PLXNB3,PPARA,PROX1,SAMD9,SH3TC2,RASGRF2,RNASE1,ZNF532,GSTCD,ROBO1,SPIN3,KCNIP1,ZNF568,STUM,KIF21A,PPP1R9A,CHD9,SLC4A3,ZNF667,FAIM2,ZNF415,PDZD2,ENKUR,CAND2,MYCBP2,SPP1,PEG10,NACAD,KANK1,PLCB1,TACC1,ADGRL3,PCDHGC5,ARHGEF12,HEY1,TMOD1,IL34,FLRT2,ZNF177,ADAMTS9,NAV2,ZDHHC20,SENP7" Coexpression 16546165-table5 Mouse StemCell_Williams06_23genes GeneSigDB 1.73E-06 2.00E-02 6.50E-05 6.46E-04 13 21 "NUMB,PROM1,EGFR,FGFR1,FGFR3,FOXG1,RBPJ,MSI1,PAX6,SOX8,SOX6,SOX2,SOX3" Coexpression 19843711-TableS2 Human Kidney_Sallustio10_2134genes_CompleteListAnalysis GeneSigDB 1.76E-06 2.04E-02 6.60E-05 6.55E-04 328 1674 "ABAT,ABR,ACLY,RBM10,ACTN1,ADD3,AK2,C1QTNF3,SPOP,SRPX,BIN1,OGT,ANK1,PPFIA1,APBA2,APLP1,APP,SHTN1,SHROOM2,CDC14B,ARHGDIA,RGS20,CDK13,ZSCAN18,RASL11B,ATP1A1,SLC4A4,ATP1B3,ATP2A2,ATP2B1,B3GALT2,BARD1,BID,CFLAR,PROM1,ST3GAL5,RAB29,DDR1,CALM1,CAMK2G,CAST,CARS,HIP1R,USP2,INA,AIFM1,CD81,LRBA,REPS2,CDC25B,LRRFIP1,CRLF1,UBE2L6,ADGRG1,CHRNA4,SLIT2,CLCN3,CLTA,CLTB,FBXO7,TJP2,MAP4K4,FAM149A,COL4A5,COX4I1,AKAP12,HAPLN1,TENM4,FEZ1,MICAL2,SIPA1L1,VCAN,SOCS5,PDE4DIP,SDC3,PHF14,CTNND1,HDAC9,GAPVD1,DAPK1,DAPK3,BRINP1,SIRPA,ARMCX2,GSDME,NTM,G3BP2,RABGAP1L,KBTBD11,DNM1,RCAN1,ECM2,DYRK1A,RASGRP1,SIDT2,RBM12,FAM13A,EGFR,LPAR6,EIF4G2,ELN,EIF1,EMX2,PLEKHO1,GPHN,RABEPK,EPS8,CDHR1,EXTL2,ABCA8,CORO2B,EFEMP1,RACK1,PRMT5,FGFR3,AMOTL2,CAMSAP1,FHL1,SEC23B,CAP2,IP6K2,PDLIM5,STAMBP,TPK1,DKK3,GABBR1,DENND2A,AHCYL1,ERAP1,MTHFD2,WASF3,MALT1,GLDC,GLS,GLUL,OS9,FERMT2,PRRC2B,GPER1,GRIN1,NR3C1,GSN,PSIP1,GUCY1A1,GUCY1B1,HAS2,PACSIN2,HMGCL,AGFG1,HSP90AA1,ICA1,IFI16,SHISAL1,IL6ST,DIPK1A,ITGA7,JAK1,KCND3,KCNJ16,KCNK1,KCNK3,KCNMA1,KHK,KLC1,IPO5,L1CAM,LAMA2,VWA5A,SMAD9,MAP4,MAPT,MATN2,MBNL1,MBP,MEIS2,MEST,MID1,MITF,AFF1,TAGLN3,MYH7,MYO6,MYO9A,NAP1L1,FXYD6,NFIX,NOVA2,NRCAM,NTRK2,DDR2,NUCB2,PCSK5,PDCD2,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKFB3,OLA1,ABCB1,SERPINE2,SSH1,PKD1,RETREG1,PKM,PLEC,PLTP,PMP22,TRHDE,PSAT1,PRRX1,PPM1B,PPP1R1A,PPP2R5C,PPP3CB,PKIA,PRKCZ,NDUFS7,PTK2,PTPRD,PTPRG,PTX3,RAD17,RALGDS,RAP1GAP,SUSD4,RBBP6,RBBP8,MORC4,UBR7,RGS4,RNH1,PCMTD2,NEK11,RPS6KA2,STK32B,KCNIP1,CLIP1,RYR3,SARS,GALNT10,SCG5,ITSN1,PPP1R9A,ASAP3,DOCK10,SHMT2,FHOD3,ST6GAL1,SEC31A,DZIP1,LIMS2,SLC6A8,SLC8A1,RAB3GAP1,ARHGEF40,OGDHL,PALLD,USP33,TNIK,ZCCHC24,FNBP1,GLT8D1,MYCBP2,SPP1,UNC5B,ZNF423,SPTAN1,CDK19,NFASC,CLSTN2,THSD1,EPB41L3,MPRIP,PRRC2C,SYNE2,DNAJC9,PLCB1,WWC1,TBL1X,TCEA1,EHBP1,WSCD1,SATB2,TCF7L2,PCDHGC5,WDR7,SYNE1,PSD3,ARHGEF12,TF,ZFPM2,GPR161,TIAM1,TJP1,BEX4,PARD3,TP53BP2,RBFOX2,TPD52,TPM1,TPM2,METTL3,ZMYND8,NTSR2,TSC1,SSBP2,TTC3,CADM1,UBE2H,UCHL1,UGT8,DNAJC12,USP1,WNT7A,SLC13A3,ZNF24,ATP6V0E2,NDRG4,ZNF195,FTSJ1,CSDE1,TUBA1A,NAV3,TRIM16L,PHTF2,FXR1" Coexpression 20502458-TableS6b Human Sarcoma_Missiaglia10_212genes GeneSigDB 1.94E-06 2.24E-02 7.23E-05 7.18E-04 45 145 "ACTN2,ANK1,PPFIA4,ATP2A2,MYOM1,DCAF5,LRRFIP1,CFL2,MYL6B,QKI,PDE4DIP,TMCC2,DMPK,SRPK3,DUSP27,CAP2,PDLIM5,ARPP21,IP6K3,MYOZ2,GATM,CSDC2,MAP4,MID1,MYBPC1,MYH3,NCAM1,SEPT4,PKIA,EPDR1,TTLL7,RXRG,RYR1,HES6,SH3BGR,SCN3B,ZCCHC24,KIF1B,ZNF106,TPM1,TPM2,SYNPO2,FNDC5,SHD,RTN4" Coexpression M8954 Genes up-regulated in T conv from lymph node of elderly (retired breeder) mice: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "AP2A2,DGKZ,TNRC6C,N4BP2L1,BBS2,SYNJ1,FOXN3,KMT2C,IPCEF1,SOCS5,KIAA0040,ARHGEF4,IP6K1,HP1BP3,ZC3H11A,SLC12A6,KMT5B,PLEKHA1,CHST15,HRASLS5,CAB39,RAPGEF6,SESN1,GPR75,TNRC6A,KCNMB4,NR3C1,INSYN1,BACH2,KHK,LAMA2,PAXBP1,HECTD2,NCOA7,SMAD1,MBP,TM6SF1,SESN3,NCF2,NLGN3,TMIE,SPATA6,SNRK,CEP97,ZMAT4,SLC25A36,CCDC82,DOCK10,RCOR3,FAM126B,INKA2,LEFTY2,NR2C2,SSBP2,TTC3,RNF170,FRMD6" Coexpression M5381 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "ADD3,BIN1,DGKD,N4BP2L1,BID,CALM1,DGKI,DCLK1,SEC31B,SH2B1,RIPOR2,MAML1,SGSM2,USP3,EDNRA,RASGRP1,OPTN,EIF1,ERBB2,EZH1,KIAA1109,FOXO3,TRMO,TPK1,SESN1,BTN2A1,GSN,IL11RA,JAK1,KIF5C,MBNL1,MYO6,NAP1L2,OMG,PAH,KCNK10,RASGRF1,PRR5L,RYR3,KIF16B,R3HDM2,ST6GAL1,CLSTN1,INAVA,DOP1A,SYNE2,CAMTA1,FAM208A,AHCYL2,SIK3,KAT6B,TPM1,PARP6,GDPD5,MVB12B,ZNF37BP,JMJD1C" Coexpression M9269 Genes up-regulated in spleen B lymphocytes versus bone marrow plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "TKTL1,NDRG2,ADCY6,TMCC3,SORCS2,OSBPL8,AMPD3,DGKD,SEMA4G,RASL11B,TMEM108,BTK,CACNA1D,CD81,CACNA2D2,FOXN3,MYL6B,KIAA0040,DAPK1,GUCD1,FRY,EGR3,TMEM35A,CALCRL,EPB41L2,RASGRP2,KIAA1109,ZNF605,GSN,BACH2,KCNA2,STMN1,HECTD2,SRSF12,MX1,MYO6,TMIE,MINDY2,BEND5,ZDHHC14,ZYG11B,TMEM206,EMID1,IL17RB,SELL,GALNT10,TET1,TNIK,TNS1,TTC3,TUBB2A,SGK3,UBE3A,PMEPA1,CERS6,VANGL2,FRMD6" Coexpression M6018 Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "FAM135A,ZBTB10,BBS2,KSR1,SUMF2,AKAP5,OSBPL3,KIAA0040,UBXN2A,EARS2,TBC1D5,KIAA0753,TMCC2,EGR3,SRPK3,GPHN,CHST15,FKTN,GTF2IRD2,POMT1,ST6GALNAC3,GAD1,GART,DCLK2,PARD3B,ZNF496,CHIC1,ZNF862,NUMA1,PFKP,C11orf49,EXOSC10,PPM1B,MTMR10,PTK2,GTDC1,CCDC82,ZNF532,FOXRED2,MAPK12,SCN8A,ZFP2,ZNF365,RAB3GAP1,ATF7IP,FAM126B,DOP1A,DDHD2,DNMBP,DMXL2,ARHGEF12,FRYL,RGMB,TRPM2,RFTN2,TTC3,ZFP41" Coexpression M7469 Genes down-regulated in CD4 [GeneID=920] T cells treated with IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "NDRG2,SEMA7A,CDK10,MYOM1,BACH1,SGCE,RUNX1T1,NRXN1,NMT2,SIPA1L1,CTNND1,PITPNC1,ELMSAN1,SRGAP3,FRY,YAF2,ENO2,TMEM74,HSPA12B,SLC9B2,MED12L,FGF11,FHL1,NBEA,GALC,GBX2,GHR,IRAK3,KLF12,ICA1,USP54,ADAM22,MYCN,NUCB1,OCRL,PBX1,RASGEF1B,PKIA,WBP1L,SLC6A15,TTLL7,MEG3,ZFP2,ITSN1,PEX26,GKAP1,PALLD,PLCB1,EHBP1,FRYL,TEK,TIE1,SMUG1,TSC1,CADM1,MICU3,PLSCR4" Coexpression M5034 Genes up-regulated in comparison of SP2 thymocytes versus SP4 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.99E-06 2.30E-02 7.27E-05 7.22E-04 57 200 "TTYH1,SLC12A5,ZNF608,WDR35,ARHGAP20,LRFN1,ANK2,FAM131A,ALDH7A1,AIFM1,EVI5L,CNN3,WHRN,TENM4,PLCH2,BOC,DLG4,USH1C,TNK2,ELN,HSD17B14,DLC1,CEP78,FER,FGF12,UBE2E3,TACC2,POMT1,GPR153,ADGRA1,GABRB3,TDRKH,GSN,ACOT7,KCNA6,KIFC3,MPP2,PCSK5,DUSP26,NALCN,ASPDH,PLXNB1,SYTL2,PTK2,MAPK12,ZNF821,ARX,SPTB,HIF3A,TPD52,RPL7L1,CLEC2L,EMX2OS,TMEM237,TUBA1A,TMEM63C,VANGL2" Coexpression 19843711-TableS1 Human Kidney_Sallustio10_2134genes_DiscriminatedARPCsFromRPTEC/MSC GeneSigDB 2.02E-06 2.33E-02 7.36E-05 7.31E-04 330 1688 "ABAT,ABR,ACLY,RBM10,ACTN1,ADD3,AK2,C1QTNF3,SPOP,SRPX,BIN1,OGT,ANK1,PPFIA1,APBA2,APLP1,APP,SHTN1,SHROOM2,CDC14B,ARHGDIA,RGS20,CDK13,ZSCAN18,RASL11B,ATP1A1,SLC4A4,ATP1B3,ATP2A2,ATP2B1,B3GALT2,BARD1,BID,CFLAR,PROM1,ST3GAL5,RAB29,DDR1,CACNB2,CALM1,CAMK2G,CAST,CARS,HIP1R,USP2,INA,AIFM1,CD81,LRBA,REPS2,CDC25B,LRRFIP1,CRLF1,UBE2L6,ADGRG1,CHRNA4,SLIT2,CLCN3,CLTA,CLTB,FBXO7,TJP2,MAP4K4,FAM149A,COL4A5,COX4I1,AKAP12,HAPLN1,TENM4,FEZ1,MICAL2,SIPA1L1,VCAN,SOCS5,PDE4DIP,SDC3,PHF14,CTNND1,HDAC9,GAPVD1,DAPK1,DAPK3,BRINP1,SIRPA,ARMCX2,GSDME,NTM,G3BP2,RABGAP1L,KBTBD11,DNM1,RCAN1,ECM2,DYRK1A,RASGRP1,SIDT2,RBM12,FAM13A,EGFR,LPAR6,EIF4G2,ELN,EIF1,EMX2,PLEKHO1,GPHN,RABEPK,EPS8,CDHR1,EXTL2,ABCA8,CORO2B,EFEMP1,RACK1,PRMT5,FGFR3,AMOTL2,CAMSAP1,FHL1,SEC23B,CAP2,IP6K2,PDLIM5,STAMBP,TPK1,DKK3,GABBR1,DENND2A,AHCYL1,ERAP1,MTHFD2,WASF3,MALT1,GLDC,GLS,GLUL,OS9,FERMT2,PRRC2B,GPER1,GRIN1,NR3C1,GSN,PSIP1,GUCY1A1,GUCY1B1,HAS2,PACSIN2,HMGCL,AGFG1,HSP90AA1,ICA1,IFI16,SHISAL1,IL6ST,DIPK1A,ITGA7,JAK1,KCND3,KCNJ16,KCNK1,KCNK3,KCNMA1,KHK,KLC1,IPO5,L1CAM,LAMA2,VWA5A,SMAD9,MAP4,MAPT,MATN2,MBNL1,MBP,MEIS2,MEST,MID1,MITF,AFF1,TAGLN3,MYH7,MYO6,MYO9A,NAP1L1,FXYD6,NFIX,NOVA2,NRCAM,NTRK2,DDR2,NUCB2,PCSK5,PDCD2,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKFB3,OLA1,ABCB1,SERPINE2,SSH1,PKD1,RETREG1,PKM,PLEC,PLTP,PMP22,TRHDE,PSAT1,PRRX1,PPM1B,PPP1R1A,PPP2R5C,PPP3CB,PKIA,PRKCZ,NDUFS7,PTK2,PTPRD,PTPRG,PTX3,RAD17,RALGDS,RAP1GAP,SUSD4,RBBP6,RBBP8,MORC4,UBR7,RGS4,RNH1,PCMTD2,NEK11,RPS6KA2,STK32B,KCNIP1,CLIP1,RYR3,SARS,GALNT10,SCG5,ITSN1,PPP1R9A,ASAP3,DOCK10,SHMT2,FHOD3,ST6GAL1,SEC31A,DZIP1,LIMS2,SLC6A8,SLC8A1,RAB3GAP1,ARHGEF40,OGDHL,PALLD,USP33,TNIK,ZCCHC24,FNBP1,GLT8D1,MYCBP2,SPP1,UNC5B,ZNF423,SPTAN1,CDK19,NFASC,CLSTN2,THSD1,EPB41L3,MPRIP,PRRC2C,SYNE2,DNAJC9,PLCB1,WWC1,TBL1X,TCEA1,EHBP1,WSCD1,SATB2,TCF7L2,USP22,PCDHGC5,WDR7,SYNE1,PSD3,ARHGEF12,TF,ZFPM2,GPR161,TIAM1,TJP1,BEX4,PARD3,TP53BP2,RBFOX2,TPD52,TPM1,TPM2,METTL3,ZMYND8,NTSR2,TSC1,SSBP2,TTC3,CADM1,UBE2H,UCHL1,UGT8,DNAJC12,USP1,WNT7A,SLC13A3,ZNF24,ATP6V0E2,NDRG4,ZNF195,FTSJ1,CSDE1,TUBA1A,NAV3,TRIM16L,PHTF2,FXR1" Coexpression M19488 "Genes up-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [GeneID=9260], a latent gene of Epstein-Barr virus (EBV)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.23E-06 2.58E-02 8.10E-05 8.05E-04 99 408 "CLK4,FMNL2,SLC44A5,KLHL13,ALCAM,CDC42BPA,PKP4,USP37,CADPS,ZBTB10,DDX3Y,ARHGEF7,CALB1,SPAG9,B4GALT6,NRXN1,CNR1,CP,FAM171B,RBM39,SNCAIP,PHACTR3,APPL1,RIMS2,MATR3,ZNF804A,HEPH,DMD,DYNC1I1,NR1D2,TMTC1,MBNL2,EIF4G1,F5,FABP7,SYNCRIP,USP16,MEGF10,HBS1L,MTHFD2,GATM,GHR,SPIN1,IRAK3,HNMT,HSP90AA1,C5orf24,ZNF678,KIT,LIFR,LIMS1,MATN2,MBNL1,MEST,SESN3,MYO6,NASP,NFIA,ENPP2,FAM98B,OLA1,SERPINI1,LRP12,ING3,PKN2,PTHLH,PTPN13,PTX3,OXR1,RET,SLC25A36,RPRD1A,RPE,FBXW7,SOX8,TNFRSF19,HSPA4L,SYBU,SLC12A2,SLCO1A2,CPEB4,ANKRD36,FAM126B,SON,NPAS3,POPDC3,ANKRD12,TCF4,TRIM2,WASHC4,ZMAT3,DDHD1,SSBP2,TTC3,UGT8,USP1,SYNC,PRTFDC1,NETO2" Coexpression M1741 Genes whose promoters are bound by FOXP3 [GeneID=50943] based an a ChIP-chip analysis. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.26E-06 2.61E-02 8.18E-05 8.13E-04 115 491 "ARID1A,ADD3,ESYT2,BEND6,ZNF608,WDR35,OSBPL8,CC2D2A,MRTFA,AMPH,SHTN1,ARHGAP5,CADPS,ATP1B3,ATP2B1,CADM3,SGCE,LDLRAD4,CACNB4,CAST,CDH10,RCBTB2,MS4A7,EPS15L1,HECTD1,MAP4K4,NIPBL,CREM,ANKRD44,LRIG1,ARHGEF10,USP6NL,CX3CR1,TOX,TBC1D5,ELMO1,RABGAP1L,FAM107B,KBTBD11,USP3,E2F6,EPB41,ENPP6,GPHN,RCSD1,PTK2B,FYB1,FYN,GABRG1,HBS1L,RAPGEF6,ATP8A2,SESN1,GGTA1P,MALT1,PSRC1,GPD2,ADAMTS6,ICA1,IL6ST,DIPK1A,JAK1,MBNL1,CD200,NINJ2,PDE4B,GNG2,PIK3R1,SH3KBP1,PPP2R5C,PPP3CC,CEP97,ENOX1,RBBP6,GTDC1,RFX3,RGS10,GLDN,SATB1,ATXN7,SCN8A,SELL,TRA2B,RASA3,FERMT1,DOCK10,ST6GAL1,ST8SIA1,WDR37,INTS9,SNCA,KDM3A,SPP1,CDK19,SAMSN1,SYNE2,ANKRD28,TCF12,GPRIN3,SIK3,ZFP91,KAT6B,UBE2H,AMOT,TBC1D15,WIPF1,EVI5,URM1,PPP1R3F,PARP11,C12orf4,PHTF2,JMJD1C,ZDHHC20,SNX14" Coexpression 18308945-Table1 Human StemCell_Huang08_100genes GeneSigDB 2.35E-06 2.71E-02 8.48E-05 8.42E-04 32 90 "C1QTNF4,PROM1,MAP7,B4GALT6,SLC25A27,CRHBP,CHRDL1,PAN3,HPGDS,GUCY1A1,HLF,KIT,LMO2,MEIS1,MEST,WDR49,MYCN,NAP1L3,DPY19L2P2,PDE1A,PTPRD,BAALC,ATP8B4,SCN3A,SLC2A5,PDZD2,ANKRD28,METTL3,SSBP2,GUSBP1,ZNF711,MSRB3" Coexpression 18535662-TableS1a Mouse Lymphoma_Wu08_1813genes GeneSigDB 2.39E-06 2.76E-02 8.61E-05 8.55E-04 193 913 "NDRG3,ADD3,KIDINS220,MTA3,AP2A2,OSBPL1A,TAOK1,C1QTNF3,MAP4K3,MYH7B,PPFIA1,ANXA7,APBB2,FAM131A,PHYHD1,APP,CASK,ARHGDIG,ASCL1,CHID1,ATP1B3,ATP2A2,ATP6V0A1,ADAM15,BID,ST3GAL5,SYNJ2,SGCE,CACNA1G,CALM1,CAMK2G,SPAG9,ARHGEF25,CD81,CDH2,LRRFIP1,CDO1,ADGRG1,FOXN3,CHN2,TPP1,CLTA,DNAJB5,CNN3,IQCK,COL11A2,MAGED1,CLIP3,ARHGEF10,SIPA1L1,PDE4DIP,PNPLA8,GPSM1,BOC,FGFR1OP2,TCAF1,COPS7A,SEC16A,CD99L2,CDON,FIS1,SIDT2,EFNA2,ASB3,STARD3NL,LRRC17,RASGRP2,ERBB2,SPEG,EXTL2,F3,AMZ2,RPS6KC1,TAOK3,FCGRT,FDFT1,IP6K2,VTI1B,ANKFY1,JKAMP,DPYSL4,SORBS1,NPTN,ATP6V1H,ERGIC3,SARAF,FYN,GAB1,NCKAP1,GNAS,GOLGB1,STON1,RAPGEF4,NR3C1,PRDM5,GSN,KIF3A,GSTM5,ZHX1,GABARAPL2,SMAP1,IGF1,IL6ST,JAK2,METTL21A,LAMP2,LIFR,MAT2A,MEST,CD200,CCDC80,PTOV1,TAGLN3,NFE2L2,NUCB1,NUCB2,OGDH,PENK,SERPINE2,SSH1,ZFYVE21,GPSM2,PLCD1,SMOX,PPP3CC,PRKAR1B,MAPK3,EPDR1,MAPK7,RELN,APTX,SYTL2,PTPN13,PTPRZ1,TRIM68,PRR5L,RPS6KA2,HUNK,SCP2,FNIP1,TNFRSF19,SEC14L1,GALNT10,RASA3,CHD9,FNDC3A,SEC31A,CLSTN1,RAB3GAP1,ARHGEF40,CDK5RAP3,SLC14A1,ABTB1,LIMCH1,LMBRD1,USP33,GLT8D1,SEPT8,STXBP1,SYT11,ATP11A,PJA1,TCF4,TCF7,WDR7,PSD3,TGFBR3,AKTIP,TJP1,TK2,RBFOX2,TPD52,TPD52L2,TPM1,PDSS1,AMACR,TRPS1,SSBP2,UBC,TOM1L2,VLDLR,TBC1D15,WIPF1,PORCN,NDRG4,POLR3H,MEIS3,MFF,NT5M,NAV3,MSRB3,ZDHHC20,NETO2" Coexpression M265 Up-regulated genes in the signature set for lymph node metastasis in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.44E-06 2.82E-02 8.77E-05 8.71E-04 30 82 "ADCY8,PTCH2,N4BP2L1,KSR1,ARHGEF7,CACNB4,ARHGAP33,ERBB4,CORO2B,FCGR1A,FGF1,GABRB3,DENND2A,RAPGEF1,NXPH3,KLF12,KCNJ5,BCO1,MYO7A,NNAT,PKD1,PMP2,CNNM2,SHANK2,SOX10,PCDHB6,TLL2,PIK3R5,SEZ6L,ZMYND8" Coexpression 12471243-TableS2 Human Manning02_624genes_ProteinKinases GeneSigDB 2.45E-06 2.83E-02 8.77E-05 8.71E-04 91 368 "CLK4,CDC7,ALK,MAP4K3,CDK10,CASK,CDK13,STK33,MARK4,ATM,RIPK1,KSR1,BMPR1B,BTK,DDR1,CAMK2A,CAMK2B,BRSK2,NUMBL,MAP4K4,DAPK1,DAPK3,DYRK1A,SGK2,HIPK3,EGFR,IRAK4,TNK2,SPEG,CDKL3,RPS6KC1,PTK2B,STRADA,TESK2,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,BRSK1,FYN,NEK6,GCK,TTBK1,GRK4,CIT,MAP4K5,IRAK3,MYLK2,JAK1,JAK2,KIT,MARK1,MARK3,MATK,NRBP2,NEK1,DDR2,KSR2,PAK3,CDK18,PDGFRA,CDK14,PKD1,PRKCG,PKN2,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,SNRK,RET,RNASEL,NEK11,RPS6KA2,LRRK2,HUNK,SGK1,MAST1,SRPK2,NEK4,TTBK2,TEK,TIE1,TRIO,SGK3,WNK1,PAK5,CAMK1G" Coexpression 20460542-SuppTable1 Human Colon_Dessein10_744genes GeneSigDB 2.48E-06 2.87E-02 8.87E-05 8.81E-04 152 689 "ASPHD1,ASIC1,FAM43B,FMNL2,ELFN2,KIDINS220,AGT,CEP126,CARNS1,GPRASP2,SYT13,AMT,DGKD,BCAS1,SHTN1,AQP6,SEMA4G,ARSE,CHRD,PROM1,DST,GPC2,DDR1,REPS2,LONRF2,CLU,RAB26,AKAP7,SLC25A27,COL9A3,GAL3ST1,AHCTF1,SEC31B,CDC42BPB,CRYM,MICAL2,CNTNAP2,DZIP3,GPRASP1,MYADM,DBN1,HEPH,MYEF2,CEP170,FBXO25,FAM107B,SEC16A,KBTBD11,ARRDC4,ABCC5,SEZ6L2,EEF1A2,KLHL5,SIDT2,PHF20L1,SORBS3,EPB41L2,DMTN,LRRC23,F5,FDFT1,PPP1R1B,FGFR3,MEX3B,EVL,TACC2,OGA,GCNT2,ADAM28,TOX3,RAB40B,GOLGB1,GRB10,DIDO1,PARD3B,ADAMTS13,ATE1,GSN,GSTT2,ADAMTS6,SLC2A6,ZHX1,USP54,IL11RA,ITGA7,KHK,LSS,MBNL1,MDM4,AFF1,NRBP2,NPR2,NUCB2,OPA1,PALM,PDE4A,PFKFB2,SNX10,TMEM38A,PRIMPOL,PACSIN1,TATDN3,PPP2R5C,SLC26A11,PRODH,SYTL2,ZNF493,PRRT2,ZNF532,LGR4,SOX8,ATXN1,HKDC1,ST6GAL1,LIMS2,SLC12A2,ZNF334,BTBD7,RCOR3,KIF13A,PALLD,TMCC1,TRERF1,FNBP1,THSD1,ZC4H2,STX1A,KLHL7,ABCC8,ARHGEF9,ARC,ASTN2,TACC1,ROBO3,TCF7L2,PCDHGA2,PSD3,THRA,TNNT1,TPM1,STXBP4,ANKRD20A2,CCDC14,CLDND1,NPDC1,ZNF138,ZNF177,HNRNPA3,GJC2,NLRP3,FXR1,SENP7" Coexpression M3837 Down-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.60E-06 3.00E-02 9.24E-05 9.18E-04 125 545 "NDRG2,PLA2G6,C1QTNF1,SEMA6A,LTBP4,AMPD3,AMT,OGT,GAS7,APOC1,ATP1A2,ATP1B3,ATP2B3,IL33,RGN,CD81,CDH2,LGI1,DLGAP1,RCBTB2,NRXN1,CREM,CRHBP,ABCG1,CSF1,MICAL2,VCAN,CTH,RIMS2,CYBB,GPRASP1,HDAC4,RASSF2,SPOCK2,SIRPA,HEPH,SV2B,SRGAP3,SGSM2,CHRDL1,EEF1D,EGR3,SORBS3,PLEKHO1,ST3GAL6,FGF12,FHL1,SORBS1,DKK3,GABBR1,ZMYND11,INPP5K,ALDH1L1,CSDC2,GGT5,POLL,LUZP2,GPM6B,RAPGEF4,KCNA4,KCNJ5,KCNK3,KCNN2,KIF5C,LAMA2,VWA5A,MAOB,MEIS2,ADAM22,MSRA,MYO7A,NBL1,PCSK2,PDGFRA,ABCB1,DUSP26,PHKG1,FXYD1,PLP1,PLTP,PLXNB3,SEPT4,LRRN3,MAPK10,CNNM2,WBP1L,PTCH1,PTH1R,ACSM5,PID1,OXR1,KLHDC8A,BAALC,RPL38,ZNF331,SCN7A,IL17RB,FERMT1,SMTN,SIRT2,INTS9,TMCC1,PDZRN3,CLUAP1,LHPP,CEP68,ROBO3,TEK,SIRT1,TK2,KAT6B,TNS1,UBTF,DNAJC12,FLRT1,LMF1,VSNL1,PORCN,SF1,FTSJ1,SEMA3B,PAK5,FAM182B,ADAMTSL3,SSPN" Coexpression M13061 Genes selected in supervised analyses to discriminate cells expressing E2F3 [GeneID=1871] from control cells expressing GFP. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.82E-06 3.26E-02 9.99E-05 9.92E-04 66 245 "HACE1,ADGRB2,NIPA1,DIS3L,B4GALT6,ABCG2,RAB26,TMEM155,LRIG1,ATRNL1,TSPAN5,EEF1A2,PCOLCE2,USPL1,ENO2,CEP78,FGFR3,CAMKK2,KHDRBS3,CSPG5,NSG1,FAXC,GLRB,KDM2B,GNAL,GNAS,TPPP,PSIP1,FAM222A,UBE2QL1,SLC35G1,METTL21A,TM6SF1,KCTD6,NASP,TMOD2,PFKFB3,RETREG1,KCTD15,EPB41L4B,PTCH1,NCR3LG1,RAVER2,SCN8A,IL17RB,MRAS,SH3BGR,FERMT1,GKAP1,KDM4B,PEG10,CDK19,STXBP1,GSE1,DNAJC9,SIN3B,TIAM1,HEY1,UGT8,LYPD6,REEP1,EML6,ZNF195,SLC30A4,PHTF2,NETO2" Coexpression 17234769-TableS2b Human StemCell_West07_669genes GeneSigDB 2.82E-06 3.27E-02 9.99E-05 9.92E-04 122 530 "NDRG2,PLA2G6,C1QTNF1,SEMA6A,LTBP4,AMPD3,AMT,OGT,GAS7,APOC1,ATP1A2,ATP1B3,ATP2B3,IL33,RGN,CD81,CDH2,LGI1,DLGAP1,RCBTB2,NRXN1,CREM,CRHBP,ABCG1,CSF1,MICAL2,VCAN,CTH,RIMS2,CYBB,GPRASP1,HDAC4,RASSF2,SPOCK2,SIRPA,HEPH,SV2B,SRGAP3,SGSM2,CHRDL1,EEF1D,EGR3,SORBS3,SRPK3,PLEKHO1,ST3GAL6,FGF12,FHL1,SORBS1,DKK3,GABBR1,ZMYND11,INPP5K,ALDH1L1,CSDC2,GGT5,POLL,LUZP2,GPM6B,RAPGEF4,KCNA4,KCNJ5,KCNK3,KCNN2,KIF5C,LAMA2,VWA5A,MAOB,MEIS2,ADAM22,MSRA,MYO7A,NBL1,PCSK2,PDGFRA,ABCB1,DUSP26,PHKG1,FXYD1,PLP1,PLTP,SEPT4,LRRN3,MAPK10,CNNM2,PTCH1,PTH1R,ACSM5,PID1,KLHDC8A,BAALC,RPL38,ZNF331,SCN7A,IL17RB,FERMT1,SMTN,SIRT2,INTS9,TMCC1,PDZRN3,CLUAP1,LHPP,CEP68,ROBO3,PCDHGC5,TEK,SIRT1,TK2,TNS1,UBTF,DNAJC12,FLRT1,LMF1,VSNL1,SF1,FTSJ1,SEMA3B,PAK5,FAM182B,ADAMTSL3,SSPN" Coexpression M6782 Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.95E-06 3.41E-02 1.04E-04 1.03E-03 174 811 "CLK4,BRAP,MTUS1,MRTFA,AMPD3,MAP4K3,SHTN1,NCOA1,NUMB,ATP2B1,N4BP2L1,BACH1,DST,ARHGEF7,MTMR3,RAB29,PTBP2,SPAG9,CBFA2T2,SYNGR3,ARHGEF2,CDC42,NPIPA1,SRSF11,CLU,FAM189A2,NIPBL,SLC4A7,RBM39,HINFP,PDE4DIP,FAM169A,CTH,PUM1,IST1,IP6K1,ARMCX2,ZEB2,PLEKHM1,CNIH3,NR1D2,DMTF1,ABI1,RCAN1,DNAJB6,ABCC5,HIPK3,FEM1B,OPTN,FAM13A,MBNL2,EIF5,RGS17,DCTN4,USPL1,EIF1,CDKL3,EZH1,WAC,RPS6KC1,ST3GAL6,SEC24B,FGFR1,IP6K2,TRMO,SORBS1,UFM1,TRIM16,CELF1,OGA,STAG2,ZNF274,MTHFD2,GK,RAB40B,GOLGB1,PRRC2B,GRB10,BTN2A1,FICD,MAP4K5,MUM1,KLF12,HSF2,HSP90AA1,IFI16,IGFBP1,TJAP1,IL6R,KCNK1,KPNA5,ARHGAP12,LSS,MARK3,MBP,KITLG,MKLN1,MXI1,MYO9A,NCF2,NFE2L2,NFYA,CNOT4,PFKFB3,CCSER2,PKD1,PLCD1,SMOX,ZNF426,PMP22,RETREG2,FA2H,MAPK7,RELN,GON4L,PTHLH,PTX3,RIPOR1,PLEKHB2,RALGDS,BSDC1,SLC25A36,DCUN1D2,SETD5,AP1AR,SFPQ,HSPA4L,SCG5,FAM102A,WDR47,SLC6A8,ATF7IP,TTC17,PALLD,TMCC1,KDM4B,PDZD2,KDM3A,SP2,CDK19,ZBTB43,TSPYL2,CAMTA2,LARP4,TTBK2,RGL1,STX1A,GSE1,JMJD6,ANKRD12,TAF9,TCF7L2,SIK3,SIRT1,GPR161,HEY1,TJP1,TP53BP2,NR2C2,TSC1,ZKSCAN5,TUBB2A,UBE2H,TBC1D15,CLIP2,WRN,ZNF24,SYNC,PRDM10,RNF103,NAV2,WIPF2,JMJD1C,FXR1" Coexpression M6826 Genes down-regulated in monocytes: untreated versus anti- FcgRIIB. MSigDB C7: Immunologic Signatures (v6.0) 3.18E-06 3.68E-02 1.12E-04 1.11E-03 48 161 "PLA2G6,OGT,CDC42BPA,TNRC6C,SCAPER,HAP1,LRRFIP1,EPS15L1,SLC4A8,IFFO1,NCOR1,PPP6R2,ZFYVE16,MTX3,DMTF1,AASDH,FRY,SORBS3,GPHN,ATP8A1,SGIP1,NBEA,BRPF3,TNRC6A,DCLK2,CNTRL,KLC1,STXBP5,ARHGAP12,MEIS2,PDE4A,PMS2,POLG,PTPRD,ARID4A,CHD9,SMTN,RUFY2,SON,KDM3A,PHLDB1,TIAM1,R3HDM1,CABIN1,WNK1,PRDM2,PRDM10,NAV2" Coexpression M18441 Genes down-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.20E-06 3.70E-02 1.12E-04 1.11E-03 65 241 "CDC42BPA,ANK3,CDC14B,CFLAR,BMPR1B,ARHGEF7,CACNB2,SPAG9,SEPT7,FOXN3,QKI,MAP4K4,ARMC8,ARHGEF10,SEC14L5,DLC1,PDLIM5,NSG1,IP6K3,ZNF638,KLF12,LINC00667,USP54,KCNQ2,LAMA2,LSAMP,MAPT,NDUFA5,NEK1,DPY19L2P2,EPN1,SUSD4,ZNF493,RBBP6,SLC25A36,RORB,PCMTD2,ARMH4,PPP1R9A,PAAF1,ATF7IP,CPEB4,GKAP1,COA1,INAVA,SNRPN,FAM126B,PDZD2,ZBTB43,KANK1,TACC1,PCDHGA10,PCDHGA4,SYNE1,PSD3,HEY2,CA14,TTC3,ETNPPL,ZNF189,SLC38A1,STOX2,SMIM8,DPF3,CPNE4" Coexpression M1810 Cluster G6: genes increasingly down-regulated in NHEK cells (normal keratinocyte) after UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.23E-06 3.74E-02 1.13E-04 1.12E-03 46 152 "MTUS1,SPOP,ATP2B1,BCL7A,ARHGEF7,USP6,QKI,MICAL2,EDRF1,DOCK4,RABGAP1L,GNE,E2F5,VPS13B,SUCO,FOXO3,FYN,ZNF638,FERMT2,NR3C1,RBPJ,KIF2A,MEIS1,MN1,CNOT4,PTK2,REV3L,SLC25A36,CHD9,FNDC3A,DOP1A,AJAP1,PRRC2C,MTCL1,WWC1,CLASP1,DOCK9,FRYL,KAT6B,ZMYND8,SSBP2,FLRT2,VLDLR,XPO1,NAV3,KAT6A" Coexpression M6690 Genes up-regulated in fibroblasts: interferon alpha versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 3.32E-06 3.84E-02 1.16E-04 1.15E-03 51 175 "AS3MT,SNX32,HACE1,CARNS1,APAF1,GAS7,APLP1,NCOA1,DCAF5,LRBA,DCLK1,CRY2,CSF1,CX3CR1,ZEB2,SRGAP3,RABGAP1L,ARNT2,PTK2B,CHST15,MED12L,FYN,NEK6,GPM6B,RAPGEF1,ADAMTS6,ZDHHC15,STXBP5,PIK3AP1,GPR155,XRN1,PMP2,PPP3CA,BCAS3,SYTL2,TMEM104,PTPN13,PTPRE,RGS3,FBXW7,RXRA,SEMA6D,ASRGL1,MAPKBP1,SAMSN1,SULF2,FRYL,SIK3,ZBTB38,GDPD5,TMEM163" Coexpression M13809 Genes up-regulated in the samples with intrahepatic metastatic hepatocellular carcinoma (HCC) vs primary HCC. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.34E-06 3.86E-02 1.16E-04 1.15E-03 123 537 "RBM10,C3orf14,CDC7,PKP4,DGKZ,CDK13,ASPH,BARD1,MTMR2,CA12,ARHGEF1,CBFA2T2,ARHGEF2,NUMBL,CLTB,MAP4K4,COL11A2,FAM171B,SH2B1,CSNK1E,VCAN,CTNND2,PHF19,KIAA0513,DBN1,DNAJC6,MYEF2,B3GAT3,RHOBTB1,SLC29A4,DTNA,DUSP9,DNM1L,EEF1A2,PLXNC1,ENO2,MFSD10,RACK1,GORAB,SYNCRIP,FOXM1,EFCAB2,ZCCHC17,ZNF234,MTHFD2,SEPT9,GLS,TOX3,MAP7D2,GNAS,GNG4,PRRC2B,RAPGEF1,SLC2A6,GYG1,PACSIN2,ATXN2L,KCNH2,KIF2A,MAP2,MAP4,MBNL1,SCAMP5,DDX25,NACA,NRCAM,ZNF827,PCSK5,PDCD2,PFKFB4,OLA1,SERPINE2,PKM,SMOX,C11orf49,PTPA,MAPK3,VPS13C,SUSD4,FIGN,TTLL7,SLC25A36,ZNF532,C12orf49,ROBO1,GLDN,HUNK,ASRGL1,PPP1R9A,FERMT1,HKDC1,FHOD3,SLC6A8,ARFGAP1,SMARCE1,SNAP25,SNRPN,TMCC1,EMC1,ZNF302,PLCB1,POPDC3,MTCL1,ATP13A2,C18orf54,CBX5,DDHD1,KCTD2,TPD52L2,TPM2,TRPC1,TRPS1,SSBP2,TUBB2A,UCHL1,MEAF6,NSD2,ZIC2,ZFP41,TMEM237,STOX2,NAV3,NETO2" Coexpression 18614019-TableS4d Mouse StemCell_Fazzio08_1078genes GeneSigDB 3.70E-06 4.28E-02 1.28E-04 1.27E-03 143 645 "ADCY2,AXIN2,ALCAM,SEMA7A,VAT1L,CPNE5,MARCH3,NCOA1,KSR1,DST,MMD2,FOXK1,CALB1,SLC25A14,CAPN3,CH25H,CBLN1,RGN,EVI5L,DLGAP1,CCPG1,CHGA,SLIT2,CLU,VAX2,SLC32A1,CRYM,PHACTR3,CNTNAP2,CYBB,ACY3,BRINP1,DCC,C2CD2L,FAM107B,DYNC1I1,ECM2,FEM1B,EEF1D,AASS,ELAVL3,PCOLCE2,LRRC17,RCSD1,TUBB3,SCML2,FCGRT,FGF1,BAIAP2,HPCAL4,ATP13A4,TMEM175,DPYSL4,ZCCHC17,TPPP3,ZMAT1,GABRA1,CAB39,DISC1,ACSS1,RND1,GLUL,OS9,GPD1,PCLO,GRM5,FICD,NCKAP1L,GABARAPL2,HP,BTBD17,MYLK2,OLFM3,KCNN2,ASPRV1,EFHB,MEIS2,MSRA,SCG3,NINJ2,NPY,NPTX2,DDR2,TREM2,PCDH8,PCDH9,PLCD1,MAGEL2,SH3KBP1,NKAIN4,RASGEF1B,SKOR1,RELN,PTPN13,PTPRE,PTPRO,TMEM231,MARCH1,PLEKHB2,ZCWPW1,CRTAC1,ROBO1,RXRA,RXRG,RYR3,CSRNP3,SMPD3,HKDC1,PREX2,SLC6A8,SLC11A1,EPC1,LIMCH1,ZHX3,LHPP,STOX1,THSD1,APOM,ACSBG1,RHBDL3,POPDC3,ROBO3,ADGRL3,DOCK9,SLC19A3,ZNF106,DDHD1,RIMBP2,TNS1,NPL,IL34,TRH,DCBLD1,AMOT,FAM181B,VAV1,CFAP52,AMZ1,EPM2A,TMEM63C,NETO2,DPF3,CPNE4" Coexpression M1369 Predicted targets of SOX9 [GeneID=6662] that are down-regulated during early prostate development. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.73E-06 4.31E-02 1.28E-04 1.27E-03 20 45 "SLITRK1,CDC27,SLIT2,ZNF521,CRMP1,PUM1,RASSF2,ELAVL4,OLFM1,HMGB1,IGF1,STMN1,MEIS1,NASP,NFIX,PCDH18,SYT4,TCF4,TIAM1,RBFOX2" Coexpression M9924 Genes up-regulated in B lymphocytes: untreated versus anti-IgM for 24h. MSigDB C7: Immunologic Signatures (v6.0) 3.73E-06 4.31E-02 1.28E-04 1.27E-03 56 199 "ADORA3,AMH,EPB41L5,CACHD1,CPNE5,MYRF,NMT2,CNTN1,SLC4A7,SLITRK5,SCRN1,DBN1,RUSC2,HS3ST2,RASA4,TBC1D16,FLNC,TPPP3,GABRG2,TUBA8,AHDC1,PCDH17,KCNMB4,TDRKH,CIT,PSIP1,HLF,KCNF1,KIF5C,KIT,MID1,MOV10,MYT1,NOS1,NPTX2,OPRL1,PC,PCDH9,FXYD1,HYDIN,PTPRN,ROGDI,SLC6A15,DUSP15,TTLL7,UEVLD,ATXN1,SLC8A1,SLC11A1,USP33,HECW1,ZNF423,STAC2,HEY1,SCG2,ST8SIA2" Coexpression M5413 Genes up-regulated in comparison of eosinophils versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 3.73E-06 4.31E-02 1.28E-04 1.27E-03 56 199 "ALCAM,FAM131A,CADPS,MARCH3,CAMK2B,LRRFIP1,RAB33A,SH2B1,CSF3R,PLCH2,CYBB,DOCK4,SIRPA,ACOT8,ANKRD46,CNNM1,PLXNC1,FCGR1A,FGFR1,CELF1,GAA,GALC,TMEM8B,NEU3,GLUL,HMX1,HTR2A,INPP5B,CDH20,MBP,MYO5A,P2RY13,OGDH,KLK6,SYTL2,FAM184A,RBBP8,RERGL,ROM1,LGR4,HUNK,TMEM156,FOXRED2,STUM,ARHGEF40,SLC11A1,WDTC1,ATP10B,ARC,MCF2L,SYNE1,ZFPM2,THBS4,TUB,UGT8,SSPN" Coexpression 18713946-TableS3 Human Lymphoma_Sander08_1021genes GeneSigDB 3.82E-06 4.42E-02 1.31E-04 1.30E-03 134 597 "ABAT,KLRC4,MTUS1,AMPD3,ANXA7,APBB2,ZBTB10,NCOA1,NUMB,STX16,SLC2A11,RIPK1,BID,BLM,CFLAR,ARHGEF7,CACNA1A,PTBP2,CBS,ARHGEF2,CLGN,CHN2,MS4A7,KMT2C,RAB33A,LY86,PDE4DIP,CTH,ARHGAP24,PHF19,HP1BP3,SACS,DPYSL2,MBNL2,KMT5B,PLXNC1,VPS13B,FER,CAMSAP1,PCYOX1,EVL,TMEM107,PDLIM5,NPTN,OGA,ZMAT1,ZMYND11,ACSS1,KIAA1841,SESN1,RND1,GLUL,ZNF638,ZNF782,EID2B,LRRCC1,IL6ST,ITGAV,KLRC3,LYPLAL1,MEF2C,MIA2,MKLN1,AFF1,MPP2,N6AMT1,NASP,NDUFA5,NINJ2,CNOT4,OXTR,ZNF655,PSAT1,ING3,PILRA,PRKACB,CEP41,SLC26A11,SAMD9,VPS13C,SIDT1,PTPRE,OXR1,SEC61A2,ZNF532,SETD5,RPS6KA2,KCNIP3,TMEM156,MRAS,CHD9,R3HDM2,WDR37,FAM81A,ATF7IP,CPEB4,GKAP1,TTC17,SNRPN,PALLD,SOX5,KIF21B,FNBP1,PBLD,FGD4,DNAJC9,TCF12,WASHC4,FRYL,ITGB3BP,ZMAT3,TLR4,TMPO,NPL,ZNF346,TRIO,TTC3,UBE2H,USP1,TBC1D15,NSD2,RICTOR,KCNK12,XRCC4,ZNF711,LRP8,SLC38A1,PLD4,GOPC,JMJD1C,RSPRY1,TTC7A,ZDHHC20,SENP7" Coexpression 16318415-TableS1 Human Kidney_Zhao06_259genes GeneSigDB 3.87E-06 4.48E-02 1.32E-04 1.31E-03 61 223 "SYN3,MTUS1,CC2D2A,SEMA6A,ANK3,LDB2,CD86,CDH8,IQCK,NECTIN3,ANKRD44,PDE4DIP,ELMO1,FBXO25,RHOBTB1,EBF1,EDN1,EDNRB,TMTC1,OPTN,FAM13A,PCOLCE2,SH3YL1,FLT1,PPARGC1A,GNAS,GRB10,FRMD3,HLF,ACOT7,SYNPO,L1CAM,LIFR,MEF2C,MID1,MYO9A,NFIA,NPTX2,ENPP2,MASP1,VEPH1,TTLL7,SGK1,SYBU,SLC1A3,PPP4R3A,SOX5,ARHGAP26,RGL1,NSFL1C,PLCB1,TACC1,EHBP1,TCF4,SIK3,TGFBR3,NPL,UBE3A,ZNF189,ZNF248,NHSL1" Coexpression 19567819-SuppTable1 Human Leukemia_Gross09_279genes GeneSigDB 3.95E-06 4.57E-02 1.35E-04 1.34E-03 68 257 "ACLY,ACTN1,ADD2,PLEKHH1,SRPX,PCDH10,DGKZ,APOC1,API5,RGS20,KIF1A,ST3GAL5,PRMT9,CA8,CALB1,CALB2,CALM1,ARHGEF6,MAGED1,PDE4DIP,CTNND2,KCTD8,DBN1,RCAN1,EIF5,GPHN,RACK1,UFM1,FYN,GAD1,MSTN,AP4S1,LINGO1,HBA1,AGBL5,INPP1,SYTL4,MATK,MEST,AFF1,NRGN,GLIPR1L2,PCMT1,PIK3CD,PMP22,PRKCZ,RELN,RAB3IL1,RBBP6,HKR1,SPIN3,ST6GAL1,KBTBD4,TET1,DBNDD2,ZNF302,ARHGAP9,RNF175,HEY1,WBP2,UBC,SLC35A4,CCDC136,CLIP2,ZNF138,DNALI1,KCNAB1,TMEM163" Coexpression 20630075-AF-3 Mouse StemCell_GarciaEscudero10_311genes_p53 GeneSigDB 4.00E-06 4.62E-02 1.36E-04 1.35E-03 62 228 "ACADM,ACTN2,NDRG2,ABCD2,BBOX1,ANK1,AQP4,ASPH,ATP1A2,MYOM1,ADAM23,BCHE,USP2,MYOM2,CDO1,AKAP6,GAL3ST1,PDE4DIP,DCT,EDN3,EEF1A2,KATNAL1,MRVI1,TMEM132C,SORBS1,PDLIM5,GALNT15,IP6K3,MYOZ2,TXNL4A,GPD1,GPM6A,NR3C1,GSN,COQ10A,ELOVL5,ITPKB,MBP,MYBPC1,NFIA,PGAM2,TMEM38A,FXYD1,MINDY2,NDUFS7,PYGM,CLIP1,RYR1,SATB1,SCN4B,SCN7A,SH3BGR,LIMS2,EFHD1,ADHFE1,TRIM2,TIMP4,TPM2,SYNPO2,ZIC1,PROCA1,WNK2" Coexpression 17952126-SuppTable1 Human Bladder_Buytaert08_832genes GeneSigDB 4.03E-06 4.66E-02 1.36E-04 1.35E-03 172 804 "CLK4,BRAP,MTUS1,MRTFA,AMPD3,MAP4K3,SHTN1,NCOA1,NUMB,ATP2B1,N4BP2L1,BACH1,DST,ARHGEF7,MTMR3,RAB29,PTBP2,SPAG9,CBFA2T2,SYNGR3,ARHGEF2,CDC42,SRSF11,CLU,FAM189A2,NIPBL,SLC4A7,RBM39,HINFP,PDE4DIP,FAM169A,CTH,PUM1,IST1,IP6K1,ARMCX2,ZEB2,PLEKHM1,CNIH3,NR1D2,DMTF1,ABI1,RCAN1,DNAJB6,ABCC5,HIPK3,FEM1B,OPTN,FAM13A,MBNL2,EIF5,RGS17,DCTN4,USPL1,EIF1,CDKL3,EZH1,WAC,RPS6KC1,ST3GAL6,SEC24B,FGFR1,IP6K2,FOXO3,SORBS1,UFM1,CELF1,OGA,STAG2,ZNF274,MTHFD2,GK,RAB40B,GOLGB1,PRRC2B,GRB10,BTN2A1,FICD,MAP4K5,MUM1,KLF12,HSF2,HSP90AA1,IFI16,IGFBP1,TJAP1,IL6R,KCNK1,KPNA5,ARHGAP12,LSS,MARK3,MBP,KITLG,MKLN1,MXI1,MYO9A,NCF2,NFE2L2,NFYA,CNOT4,PFKFB3,CCSER2,PKD1,PLCD1,SMOX,ZNF426,PMP22,RETREG2,FA2H,MAPK7,RELN,GON4L,PTHLH,PTX3,RIPOR1,PLEKHB2,RALGDS,BSDC1,SLC25A36,DCUN1D2,SETD5,AP1AR,SFPQ,HSPA4L,SCG5,FAM102A,WDR47,ATF7IP,TTC17,PALLD,TMCC1,KDM4B,PDZD2,KDM3A,SP2,CDK19,ZBTB43,TSPYL2,CAMTA2,LARP4,TTBK2,RGL1,STX1A,GSE1,JMJD6,ANKRD12,TAF9,TCF7L2,SIK3,SIRT1,GPR161,HEY1,TJP1,TP53BP2,NR2C2,TSC1,ZKSCAN5,TUBB2A,UBE2H,TBC1D15,CLIP2,WRN,ZNF24,SYNC,PRDM10,RNF103,NAV2,TRIM16L,WIPF2,JMJD1C,FXR1" Coexpression 18714397-TableW1 Human Ovarian_Park08_77genes GeneSigDB 4.04E-06 4.67E-02 1.36E-04 1.35E-03 24 60 "CLK4,SPARCL1,CAMK2G,CAST,MS4A7,CLU,BOC,ECM2,EDIL3,TUBD1,FAM198B,SCARA3,NR3C1,LIX1,KIT,MEIS2,MX1,CNTN3,PIK3R1,RNASEL,CPEB4,LIMCH1,SULF2,ZEB1" Coexpression 12509443-Table2 Human ProteinKinases_Frevel03_425genes GeneSigDB 4.12E-06 4.77E-02 1.39E-04 1.38E-03 96 398 "ABR,ACADM,CDC7,MADD,DDX3Y,EIF4G3,ATP2A2,BCL2L2,ARHGEF7,MTMR2,OSGIN2,BSN,PRC1,CBLN1,USP6,NEURL1,CDC27,CDC42,NPIPA1,SRSF11,NMT2,RNF14,VCAN,KIAA0040,PPP6R2,TOX,TOMM20,DBT,YTHDC1,RUSC2,SMG7,G3BP2,KBTBD11,GNE,DYRK1A,GOLT1B,EDN3,EDNRB,DMTN,SRRM1,VPS26C,SIRPB1,F3,PTK2B,PDLIM5,NPTN,GALC,MTHFD2,GLS,GRB10,NR3C1,BTN2A1,IDH3A,IGF1,ITGAV,MATN3,MEF2C,AFF1,MPP2,MTR,NCAM2,NFE2L2,NOVA1,OGDH,PDE4B,PIK3CD,PLCL1,STRN3,POU6F1,PPP3CA,PPP3CB,RBBP8,ITSN1,FNDC3A,WDR37,ZNF365,SNAP25,ZBTB43,ITPRID2,STAU1,NEK4,ARHGEF9,TACC1,ATMIN,TCF12,PCDHA6,SIRT1,AKTIP,TPD52,UBE2H,NSD2,LRP8,EVI5,SEMA3B,NAV3,IFT88" Coexpression M10575 Genes exclusively down-regulated in fibroblasts expressing the XP/CS mutant form of ERCC3 [GeneID=2071] after high dose UVC irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.19E-06 4.85E-02 1.41E-04 1.40E-03 31 88 "APBB2,DST,BTRC,CDH2,SLIT2,NECTIN3,ARHGEF10,PHF14,DOCK4,CTIF,ZEB2,E2F5,VPS13B,PDLIM5,ATP2C1,AHDC1,MALT1,AGFG1,PIK3C2A,PTX3,WDR37,TMCC1,SON,GSE1,FAM168A,DOCK9,TGFBR3,FAM155A,VLDLR,INTS3,NAV3" Coexpression M9245 Genes up-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]. MSigDB C7: Immunologic Signatures (v6.0) 4.20E-06 4.86E-02 1.41E-04 1.40E-03 55 195 "INTS2,CEP126,MADD,ZSCAN18,EIF4G3,CDK5R1,DDR1,CD81,CHN2,ABCG1,ATRNL1,DZIP3,ARHGAP24,TBC1D5,GIT2,ELMSAN1,DMD,TRAPPC9,TOM1,SIDT2,EPB41,RASGRP2,RCSD1,TMEM164,CELF1,TVP23A,GABBR1,DCLK2,CLASRP,BACH2,IFI16,ITGAM,STXBP5,ZFYVE27,ERICH3,BLOC1S2,NUMA1,PRKACB,VPS13C,RIPOR1,TMEM231,MARCH1,KHDRBS2,GTDC1,SATB1,ST3GAL3,FAM81A,PDLIM2,SIK3,ARL10,ZNF610,LAT2,SF1,ZNF28,MAP3K12" Coexpression M7327 Genes down-regulated in neurons after NPAS4 [GeneID=266743] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.39E-06 5.08E-02 1.42E-04 1.41E-03 26 68 "FAM131A,OSGIN2,SLC4A7,CRHBP,SV2B,EGR3,ELAVL4,ARPP21,RAB40B,GPR22,HPCA,ITPKA,KCNA1,KCNA4,LMO2,NPTX1,NPTX2,CRTAC1,RGS4,KCNIP2,LINC00461,SORCS3,SEPT8,ARC,DICER1,VGF" Coexpression M8975 Genes up-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg2 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "TMEFF1,ARRB2,RGS9,PTBP2,FADS2,BAG4,CTNND2,SEC14L5,RIMS3,GIT2,TIAM2,FBXL5,USH1C,B3GAT1,GLRB,DCLK2,STON1,IL6ST,MBNL1,MN1,MOG,MT3,MYH7,NEFM,PDE3A,PDGFRA,GPR173,PPARA,PRODH,C1orf109,ACSM5,ACSS3,RASGRF1,CCDC25,TRIM46,NUBPL,IGSF9B,PDZRN3,ZHX3,VAMP1,VPS13A,SYT5,DDHD2,KLHL4,TCF7,DOCK9,PIK3R5,TMPRSS5,UBTF,XRCC4,ZNF195,ZNF225,EVI5,CAB39L,PLSCR4,FZD3" Coexpression M6261 Genes down-regulated in CD4 [GeneID=920] T cells: healthy versus CLL (chronic lymphocytic leukemia)l. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "SLITRK1,AP2A2,PITPNM2,AMPH,ANK1,ARMC12,ZFYVE28,BLM,MTMR3,CAMK2G,CRHBP,CSF1R,TIAM2,NTM,CELSR3,ELN,EML1,LRRC23,EXTL1,FABP7,TBC1D16,FGR,B3GAT1,GABRA5,ADAM28,USP19,DBF4,PCDH11X,PTGDR2,KCNJ5,KCNK2,SRSF12,GLIPR1L2,GPR85,GDAP1L1,NALCN,RELN,PTPRG,SUGCT,CSRNP3,LGI3,KDM4B,TSNAXIP1,SPART,FAM208A,KIAA0930,RALYL,DNAH7,DDHD1,BEX4,CA14,CLEC2L,BEST1,SLC13A3,URM1,SLC4A10" Coexpression M4299 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] high T cells at. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "SERPINA3,ACTN1,SPARCL1,PTCH2,TMEM108,AZGP1,LDLRAD4,LURAP1,DIRAS1,ARHGEF25,FAM19A5,AKAP6,SLC35F1,CHD5,ZEB2,ZC3H11A,SV2A,SLC29A4,EGFR,LPAR6,TENM1,EPHB1,TUBB4A,SCML2,CORO2B,FCGR3A,C2orf88,GABRB1,ADAM28,GPR12,CELF3,KCNA2,KCND2,KCNH1,MAP6,LYPLAL1,SESN3,MIR4697HG,MYO9A,NPY,PLCL1,PRKCG,PLPPR1,SATB1,SLC14A1,CLSTN2,RHBDL3,SYP,TRIM2,PCDHB7,ZFPM2,PRMT8,TRH,TRIO,PLPP4,IFT88" Coexpression M5073 Genes down-regulated in comparison of memory CD8 T cells versus naive CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "ADAR,SORCS2,TMEM263,BACH1,CCPG1,MAP4K4,CNN3,CSNK1E,APPL1,TOX,DAPK1,ARMCX4,PITPNC1,ARMCX2,DNAJC6,EGR3,PLEKHO1,SRRM1,ATP8A1,TMEM164,SESN1,RAPGEF1,GSN,ZHX1,TUBB2B,LIG4,PPM1L,FXYD7,PMS2,RETREG2,ARID4A,BEND5,ZYG11B,PCMTD2,ADAL,AP1AR,LRRTM4,FNIP1,SCAF8,MYO18A,MAGI3,SMARCC2,KIF13A,TNIK,ZHX3,RBM26,CLASP2,TCF4,KIAA0930,TCF7L2,PSD3,TF,AKTIP,TSC1,UCHL1,MEAF6" Coexpression M9273 Genes up-regulated in germinal celter B lymphocytes: MYC- [GeneID=4609] versus MYC+ [GeneID=4609]. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "ADCY6,TMCC3,SORCS2,PDZD4,MAP4K3,RASL11B,TMEM108,ST3GAL5,CNN3,KIAA0040,PHF14,DAPK1,EGR3,ANKRD13B,ATP8A1,CHST15,FOXO3,STAG2,KCNMB4,NR3C1,BACH2,IL6ST,TUBB2B,STMN1,HECTD2,MYO6,PDE4B,PIK3C2A,TMIE,ZFYVE21,PACSIN1,PTCH1,RASGRF2,BEND5,ZDHHC14,EMID1,IL17RB,MAGI3,ST8SIA1,TET1,TNIK,ZCCHC24,GSE1,TBCEL,TBL1X,TPCN2,R3HDM1,TNS1,SSBP2,TTC3,SGK3,PMEPA1,PPP1R3F,CERS6,VANGL2,FRMD6" Coexpression M4521 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "CLK4,ADD3,DGKZ,ARRB1,ATP1A1,CFAP410,CAPN3,RUNX1T1,ARHGEF1,ARHGAP33,SH2B1,PLCH2,DYRK1A,ABCC5,MRNIP,PCOLCE2,RASGRP2,WAC,SH3YL1,ATP8A1,KIAA1109,USP21,ARFGAP2,SARAF,OGA,DENND2A,MALT1,STARD3,AP4S1,IL11RA,KCND1,MN1,MYH3,PBX1,CDK18,CCSER2,VPS13C,SIDT1,RAB5B,DCUN1D2,ZNF671,RPS20,ATXN7,R3HDM2,FNBP1,MYCBP2,SST,CEP68,ASTN2,PDLIM2,CABIN1,TSC2,UBE2H,WNT7A,SF1,MARCH8" Coexpression M9184 Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus PBX1 and FOXP3 [GeneID=5087;50943]. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "ACADM,ADCY6,RNF157,ARHGAP20,GPRASP2,MAP4K3,PKP4,DDR1,MAP7,FMNL3,ZBED5,ABCG2,ABCG1,DAPK1,SHANK1,ANKRD46,PLEKHO1,EPB41L2,ARMCX1,CAP2,FLYWCH1,SPECC1,B4GALNT1,SRCAP,GOLGB1,ADAMTS6,SCIN,TUBB2B,KIT,SMAD1,SRSF12,KCTD6,CD200,MX1,RTL5,SERPINI1,TMIE,PEX5,SATB1,ATXN2,RASA3,ZFP30,ST8SIA1,SLC12A2,NFASC,AGTPBP1,TCF4,TCF7,AHCYL2,SLC44A1,TP53BP1,CDK20,TTC3,BCL2L13,PMEPA1,PARP11" Coexpression M5729 Genes down-regulated in comparison of lymph node regulatory T cells versus lymph node conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "ACTN1,ADCY6,RNF150,AP2A2,APP,NUMB,GPR146,FOXK1,CARS,MAP7,SLC5A11,PPT2,CNN3,CSNK1E,PLXNA4,DNAJC6,GUCD1,TOM1,EPB41L1,RASGRP2,CAMKK2,RAPGEF4,GSN,GATD1,HECTD2,LSS,MN1,NFE2L2,NTRK3,SETD4,TREM2,PDE3B,TMIE,GPSM2,SLC26A11,ATP8B4,EMID1,CLIP1,RYR1,SATB1,SGK1,FAM102A,SEMA4A,TCF7,SYNE1,PSD3,TGFBR3,PIK3R5,RGMB,LRTM2,KCNK12,CELF4,SLC30A4,CERS6,KLHDC1,AP3B2" Coexpression M5036 Genes up-regulated in comparison of SP3 thymocytes versus SP4 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "OSBPL1A,ANK3,ARMC12,APBB2,ALDH7A1,BCHE,KALRN,CAMK2A,EVI5L,ADGRG1,PPT2,CNN3,ZNF385A,SPOCK3,NYAP1,ABCC5,ABCC9,TNK2,KCNMB2,CEP78,UBE2E3,NRG3,CHL1,GBX2,GPR162,TOX3,CBX1,ADGRA3,HAS2,VSIG4,TJAP1,TUBB2B,MPP2,PTOV1,MXI1,NEXMIF,PALM,DUSP26,PURG,TMEM255A,FAM184A,ZDHHC14,SATB1,ARX,SSPO,TMEM151B,PSD3,HIF3A,VWCE,PRRT1,IL34,KCNE5,SSBP2,FLRT1,STOX2,TUBA1A" Coexpression M3161 Genes up-regulated in comparison of Th1 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "SLC25A25,ADCY8,ADD2,MTUS1,RGS9,BMP7,CACNG1,NGB,SLC5A11,DCLK1,CRLF1,NRXN1,CCDC151,SLC35F1,MYEF2,CD99L2,FAM57B,DTNB,DUSP9,EEF1D,RASL12,FGFR3,MAD2L2,B4GALNT1,DNER,GRIA4,ATOH8,CELF3,IGSF21,AGFG1,IGSF1,KCNQ2,INSYN2,LIFR,CNTN3,PFKFB3,CNNM2,NWD1,RGS3,RPE,ZNF354C,SH3BP2,SLC4A3,RADIL,INAVA,SST,TTBK2,FAM208A,CNTN2,TCF7L2,PARD3,LRRC24,UBE3A,FAM181B,AGMO,NHSL1" Coexpression M7901 Genes down-regulated in monocytes versus macrophages. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "PPP4R4,KALRN,SLC25A14,KIAA1549L,NIPBL,MYRIP,LRRC3B,DZIP3,CTNND2,ST18,GAPVD1,BRINP1,AIF1L,TIAM2,PLPPR4,CCDC3,RAB39B,EDIL3,MBNL2,ELAVL2,C3orf18,PAN3,CDKL3,FOXO3,CSDC2,LNX1,GP1BB,GRIA2,HLF,KCNN2,SYTL4,LSAMP,ASPRV1,MAT2A,MEF2C,MMP16,MN1,LYRM9,NCAM2,PRKACB,PTAFR,PTPRE,ACER3,RAB3GAP1,MBD5,SON,NMNAT2,UHRF1BP1L,MYCBP2,THSD1,SYN2,WASHC4,AZIN2,RGMB,TRPC1,XRCC4" Coexpression M8048 Genes down-regulated in CD8 T cells: control versus stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "RNF150,MTA3,AP1B1,ABCD2,DGKD,CAPRIN2,STX16,LRBA,RCBTB2,SOCS6,SLC25A27,PLXNA4,GAPVD1,PHF19,PITPNC1,SH3GLB1,PLXNC1,LPAR6,PLEKHA1,VPS26C,TLR7,TUBA1B,GTF2IRD2,POLK,PCYOX1,POMT1,ILDR2,PSIP1,GYG1,ARHGAP19,JAK1,STMN1,LMO2,MIA2,PTOV1,CHAMP1,PDE3B,PURG,PMS2,MAPK3,CNNM2,CYBC1,UBR7,PRR5L,GKAP1,ABTB1,SP4,CDK19,CLASP2,DNMBP,AKTIP,CBX5,TPD52,UBE2H,PDSS2,FRMD6" Coexpression M5577 Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-06 5.10E-02 1.42E-04 1.41E-03 56 200 "NDRG2,C1QTNF3,AMPD2,BIN1,DGKD,CAPRIN2,ALDH7A1,N4BP2L1,CDH10,DCLK1,CDC42BPB,DCAF8,ZNF337,HS3ST2,EEF1D,PLXNC1,IRAK4,F8,FOXO3,GAD2,SRCAP,TDRKH,GPR17,SPACA9,ADAMTS8,BTN2A1,BACH2,SCRG1,IL6R,KCNN3,KIF5A,L1CAM,ZNF862,SMIM7,PRKACB,ACSS3,ARID4A,MORC4,ZNF532,SCN8A,ST8SIA1,SLN,IFT122,MYO16,DOP1A,TSNAXIP1,CAND2,LHPP,FAM208A,PDLIM2,FLRT1,ZSCAN26,ANKS1B,SLC30A3,MARCH8,HNRNPA3" Coexpression 18812457-Table2 Mouse Viral_Mercader08_51genes GeneSigDB 4.49E-06 5.19E-02 1.43E-04 1.42E-03 17 35 "ALCAM,APP,CACNA1B,NCOR1,TENM1,ATP2C1,GABRA2,PPARGC1A,MALT1,KCND2,EML5,FIGN,RPE,SP4,PLCB1,SYT1,DMXL2" Coexpression M11581 Genes up-regulated in pilocytic astrocytoma compared to glioblastoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.49E-06 5.19E-02 1.43E-04 1.42E-03 17 35 "SERPINA3,GALNT13,ATP1A2,PLEKHB1,RASSF2,OLIG2,RTN3,DKK3,DNER,GFAP,GLUL,SCRG1,SERPINE2,SOX8,PDZD2,SOX10,TF" Coexpression M13661 The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.50E-06 5.20E-02 1.43E-04 1.42E-03 112 482 "MTA3,MTUS1,ALAD,ALCAM,ANK3,BCAS1,SFMBT2,PDXK,ARRB1,NCOA1,RASL11B,ATP2B1,DOCK11,DCAF5,BMP7,SYNJ2,HIP1R,CCPG1,CFL2,COPB2,SOCS6,CLTC,TJP2,QKI,CTNND1,CTNND2,RUBCN,DBI,MFAP3L,FBXO25,GUCD1,SGSM2,CPEB2,ABCC5,PHF20L1,MBNL2,LINC-PINT,GOLGA7,EML1,VPS13B,EPB41L2,ERBB2,ERBB4,FAM198B,ATP8A1,FGF12,FGF13,USP16,FUT9,GAB1,CAB39,MALT1,LNX1,ADAP1,ATP2B1-AS1,GRB10,DIDO1,GSN,ZHX1,ICA1,INPP1,KCNMA1,LSS,MATN3,MBNL1,COL28A1,CCDC80,NCAM2,NF1,SLC11A2,NUCB2,ZNF827,PBX1,PMP22,STRN3,EPB41L4B,NXPH1,PTPN13,RIPOR1,ZDHHC4,C12orf49,SGSM1,WLS,GALNT10,WDR37,SHANK2,SLC12A2,NAXD,LIMCH1,PDZD2,FNBP1,RAP1GAP2,NXT2,KLHL7,C3orf70,TACC1,TMEM178B,TCF4,PSD3,AKTIP,NACC2,BEX4,RPRM,GORASP1,TBC1D15,RICTOR,REEP1,SPIRE1,RNF103,CAB39L,C12orf4,FAM219B" Coexpression 21220101-FigureS6 Mouse StemCell_Newbern11_209genes GeneSigDB 4.64E-06 5.37E-02 1.48E-04 1.47E-03 48 163 "SYT13,FGD2,VAT1L,CAMK2B,PLEKHB1,MS4A7,GALNT9,CMTM5,CX3CR1,FGFR1OP2,DAPK1,DLX1,ETV1,CHST15,DPYSL4,ATP2C1,ADGRA1,MEGF10,CPLX2,PCDH17,GPR17,TMEM25,SCRG1,KNDC1,LIX1,INSM1,KCNC1,MBP,MID1,NBL1,NELL2,NPY,NPR2,NTRK2,ENPP2,DUSP26,PKM,RANBP3L,PROX1,RIMKLA,SPATA7,RGL1,SYN2,TAF6,TPM2,FLRT1,VGF,KCNAB1" Coexpression M5775 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 12 h time point that were not down-regulated at the previous time point, 10 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.69E-06 5.43E-02 1.49E-04 1.48E-03 34 101 "CACNA1E,RUNX1T1,LDB2,KIAA1549L,NMT2,SIPA1L1,RABGAP1L,NR1D2,ECM2,MAMLD1,TSPAN5,VPS13B,LRRC17,ERCC2,DLC1,OGA,FYN,HMGCL,INPP5B,KCNK2,VWA5A,MID1,PDGFRA,SSH1,PMP22,ATXN1,ZNF415,ST5,MTCL1,TRIM2,ZMYND8,FLRT2,ZIC1,TUBA1A" Coexpression M1475 Genes down-regulated in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.75E-06 5.50E-02 1.50E-04 1.49E-03 124 546 "ABAT,ACADM,ADD3,ADGRF5,BBOX1,CDC42BPA,ANK2,ANK3,ANXA7,PARG,ASPA,ALDH4A1,SLC4A4,ATP2A2,AZGP1,MPDZ,DST,RAB29,CA4,CA12,CALB1,CALM1,CLDN10,KRIT1,USP2,RGN,SLC16A4,AIFM1,SLC22A6,CLTB,RNF14,CRYM,FAM169A,CTH,PUM1,TOMM20,ARMCX2,MFAP3L,RHOBTB1,KBTBD11,NR1D2,RCAN1,DNM1L,ANKRD46,SRRM1,EPS8,ERBB4,SH3YL1,FECH,KIAA1109,FGF1,UBE2E3,CAP2,VTI1B,FOLH1,PDLIM5,FYN,AHCYL1,ZMYND11,NCKAP1,GATM,GJB1,GLDC,GLS,TOX3,RAB40B,GRB10,KIF3A,DDX19B,HMGCL,HNMT,KHK,MAOB,MIA2,MXI1,MYO6,NDUFA5,OGG1,PAH,PC,ENPP2,CDK14,ABCB1,SERPINI1,PIK3C2A,PIK3R1,STRN3,PPM1B,PRPSAP2,PTH1R,PTPRD,QDPR,PLEKHB2,RDX,SLC25A36,ZC3H14,SALL1,SCP2,HSPA4L,SH3BGR,FNDC3A,R3HDM2,DZIP1,BTBD3,SHANK2,EFHD1,PDZRN3,CLASP2,EPB41L3,LARP4,APOM,NEK4,KANK1,VPS13A,SYPL1,TRIM2,TEK,BEX4,PARD3,TST,TUBB2A,UGT8,SLC13A3,RTN4" Coexpression 17430594-table3 Human Prostate_Chandran07_208genes GeneSigDB 4.81E-06 5.57E-02 1.52E-04 1.51E-03 42 136 "AXIN2,GPR158,EP400,PKP4,EPB41L5,CACHD1,BCAS1,NCOA1,ALDH7A1,AZGP1,BMP7,CD38,CDH10,MAP4K4,BOC,DAPK1,EGR3,EIF5,EFS,MRVI1,CAMSAP1,SORBS1,PDLIM5,CELF1,GPR75,GSTT2,HBA1,LSAMP,MN1,NBL1,NEFH,PTN,LGR4,FHOD3,SMTN,SLC20A2,CPEB4,SPP1,PSD3,SYNPO2,UBE2H,SSPN" Coexpression M12050 Genes up-regulated in hyppocampus of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.92E-06 5.69E-02 1.55E-04 1.54E-03 22 53 "AP2A2,CNTNAP1,ATP6V0A1,CDK5R1,BSN,DCLK1,ZNF445,B4GALT6,KBTBD11,DLG2,CNNM1,CAMKK2,B3GAT1,SPIN1,LINC00461,RPH3A,CPEB4,STXBP1,FBXW11,ATP13A2,SLC17A7,NETO1" Coexpression 17483311-SuppTable2 Human Brain_Beier07_320genes GeneSigDB 4.96E-06 5.74E-02 1.56E-04 1.55E-03 59 215 "SYS1,GALNT16,SLITRK1,C1QTNF3,LRCH2,ZBTB10,SLC4A4,BCL2L2,CFLAR,PROM1,SYNJ2,CACNA1A,SOCS6,STOML1,AKAP7,COL9A3,SLC4A7,RTTN,NRG2,KIAA0040,ZFYVE16,FAM13A,HSD17B14,ERBB2,FDFT1,FGFR3,MPP6,GABBR1,SALL3,LNX1,PLPP7,ADAMTS6,HNMT,INPP1,KHK,PAXBP1,MATN2,MID1,NELL2,DNHD1,SLC11A2,NRGN,PIK3C2A,CCSER2,PLTP,MTRF1L,OXR1,RLBP1,ZFHX4,ZNF532,KIF21A,ENKUR,BEX1,MESP1,WWC1,KIAA0930,AZIN2,OBSL1,TCEAL7" Coexpression M8907 Genes down-regulated in pro-B cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.18E-06 5.99E-02 1.62E-04 1.61E-03 47 159 "ADD3,GRAMD1B,PWWP2A,MTUS1,KIF6,USP28,APBB2,MARCH3,CANX,UBE2L6,LRIG1,IPCEF1,GALNT9,DBN1,DNAJC6,KLHL3,DMPK,EBI3,EVL,STAU2,DCLK2,NXPH2,AGFG1,ZIC5,MARK1,PDCD2,PDE2A,PDE4B,SH3KBP1,WLS,SEMA6D,IL17RB,ST6GAL1,SLC14A1,SLIT1,SOX11,CLSTN2,VPS13A,FRYL,HEPACAM,CADM1,USP1,VIPR2,KCNT2,NAV3,TMEM63C,SENP7" Coexpression M2505 Transcripts bound by CELF1 [GeneID=10658] in HeLa cells (cervical carcinoma). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.51E-06 6.37E-02 1.72E-04 1.71E-03 108 463 "ABAT,GPRIN1,FMNL2,NLGN4X,CNTNAP1,DDX3Y,BID,LDLRAD4,CACNB2,VXN,RUNX1T1,METTL6,CERS5,CBFA2T2,L3MBTL4,LOC730101,CFL2,CHRM1,ARHGAP22,STOML1,BTF3L4,CSF1R,CSNK1E,APPL1,BOC,TCAF1,BRINP1,DCT,SRGAP3,FAM135B,EEF1D,ENPP6,ANKMY1,ARMCX1,TBC1D16,KAT8,MAD2L2,CAMSAP1,SEC23B,AFF2,NBEA,UFM1,OGA,GALC,SYT17,ADAM28,GGT7,ZNF276,LILRA1,B4GALNT4,STON1,TUBA1C,CROCCP2,RFFL,GRIK4,CACFD1,GSN,MAP4K5,LIX1,ZNF678,ITGA7,KCNB1,KCNC2,CAMK2N2,MBNL1,MBP,MMP16,MSRA,NOVA1,NUMA1,PAK3,PENK,SERPINE2,ANLN,PLEC,SMOX,SMIM7,PPP3CC,EPDR1,PIGG,PTPRE,PTPRN2,MARCH1,FIGN,RGS3,SLC25A36,CHD9,SLC1A2,KANSL3,TTC17,IFT122,RIMS1,NFASC,MPRIP,TBL1X,ACSL6,USP22,PCDHGC5,DOCK9,NSD1,FRYL,NACC2,LRRC8A,FAM181B,NAV3,HNRNPA3,RNF170,SOCS4" Coexpression M7009 Genes up-regulated in IKZF1 [GeneID=10320] knockout: lymphoid-primed multipotent progenitors versus megakaryo-erythrocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 5.59E-06 6.46E-02 1.74E-04 1.73E-03 48 164 "ACTN1,ACTN2,ADCY6,USP28,TNRC6C,SFMBT2,ARHGAP5,FOXK1,CNN3,SLC25A27,LRIG1,HDAC4,PLEKHA1,PLEKHO1,SLC43A2,CHST15,RAPGEF6,SESN1,TDRKH,RAPGEF4,MAP4K5,BACH2,IL6ST,SMAD1,SESN3,ZC3H12B,SLC11A2,PLCB2,EML5,CEP97,BEND5,RGS10,RAVER2,WLS,SELL,ST6GAL1,ST8SIA1,DZIP1,SCMH1,TET1,CEP68,TCF7,ZEB1,TGFBR3,SSBP2,TTC3,TOM1L2,KLHDC1" Coexpression 18318837-TableS1 Human MesenchymalStemCells_Yamamoto08_1252genes GeneSigDB 5.81E-06 6.72E-02 1.80E-04 1.79E-03 180 853 "SERPINA3,NDRG2,RNF157,KIAA1211,ADORA3,ADRA1B,NLGN4X,MTUS1,AGT,SPARCL1,BBOX1,SYT13,DDO,APOC1,APOC2,BCAS1,SEMA4G,ARSE,ASGR1,ASPA,AZGP1,BCHE,RGS9,PROM1,C5,THSD7A,MAP7,CD86,REPS2,LONRF2,CHI3L2,MS4A7,RAB3C,JAM2,LHX2,CLU,NGEF,FAM189A2,COL4A5,GAL3ST1,CP,GDA,FAM169A,PLCXD3,CYBB,RIPOR2,RASSF2,RIMS3,DAPK1,AIF1L,FAM107B,CCDC3,SLC25A18,EDNRB,EEF1A2,SGK2,HEYL,PLXNC1,DMTN,ADGRV1,HSPA12B,F5,FCGR1B,FCGR3A,PPP1R1B,FGF13,FGF14,FGFR3,FOLH1,ABLIM2,PHYHIPL,GALNT15,DENND2A,IP6K3,IQGAP2,SYT17,STARD10,GATM,ALDH1L1,SULT1C4,PPARGC1A,GJB1,RND1,GLDC,AIFM3,KIAA1958,GPM6B,STMN2,GUCY1A2,GUCY1A1,VSIG4,HP,ICA1,IRF8,IGF1,IGFBP1,KNDC1,TUBB2B,ZNF385B,ITGA7,ITIH2,KLHL23,KCNJ16,KHK,KIF5C,KLRC2,KLRC3,PIK3AP1,MAOB,MARK1,LRP1B,SRSF12,MGAT3,SAMD5,MTTP,MYO7A,NAP1L1,NCF2,NPTX2,PCBP3,NRCAM,P2RX7,PAH,PDE3B,ABCB1,DUSP26,SNX10,RETREG1,FXYD1,SEPT4,PROX1,PTH1R,PTPRE,ACSM5,FAM184A,BEND5,GLDN,TMEM156,SALL1,IL17RB,SOX6,PPP1R9A,HKDC1,ST6GAL1,ST8SIA1,SHANK2,CXXC4,GKAP1,OGDHL,DMRTC1,SNAP25,SOX5,KANK1,TMEM150C,COBL,TAC1,WWC1,ANO4,WSCD1,NEU4,CUX2,TCF7L2,SLC19A3,PCDHAC2,TF,TIE1,TPD52,RUNDC3B,CADM1,DNAJC12,SLAIN1,ETNPPL,TRIM9,ZBTB16,ADAMTS9,SCG2,SIGLEC10,WNK3,DOCK8,ADAMTSL3" Coexpression M4654 Genes up-regulated in comparison of naive CD8 T cells versus PD-1 high CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.87E-06 6.79E-02 1.81E-04 1.80E-03 55 197 "ATP6V0E2-AS1,TKTL1,ACTN1,RNF157,GPRASP2,APBB1,ZBTB10,CARS,NOG,IPCEF1,ARHGEF4,USP6NL,CEP170,AK5,C3orf18,EPB41L2,SPEG,ARMCX1,SH3YL1,SCML2,HPCAL4,SARAF,ADGRA3,ZNF496,USP51,IL6R,IL6ST,SFXN5,ZNF667-AS1,MEST,NEXMIF,NELL2,NRCAM,PCSK5,RETREG1,FAM216A,LRRN3,CEP41,PKIA,FAM184A,BEND5,GAL3ST4,RFX2,SOX8,SELL,CNKSR2,EFHD1,SPART,STXBP1,ROBO3,AZIN2,RNF175,PRRT1,LMF1,MICU3" Coexpression M2773 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of ALK [Gene ID=238] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 5.89E-06 6.82E-02 1.82E-04 1.81E-03 44 146 "NDRG2,ADCY2,ADORA3,DOC2A,SEMA7A,LGR5,LDLRAD4,CAMK2A,DLGAP2,CHRM4,COL9A3,CNTNAP2,KIAA0408,HDAC9,ST8SIA3,EFNA2,LINC00599,PTK2B,PRELID3A,GABRG2,GPR162,GRM2,GPR45,HSPA1L,ITIH2,KCNJ9,BCO1,MX1,FXYD6,PCDH8,PENK,CEP41,PRODH,PRPH,PTPRZ1,RXRG,SLA,EFHD1,NMNAT2,SPTB,KAZN,TIAM1,VAV1,VAV2" Coexpression M6691 Genes down-regulated in fibroblasts: interferon alpha versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 6.00E-06 6.94E-02 1.85E-04 1.83E-03 52 183 "RBM10,ACTN1,PKP4,ARNTL,ARRB1,DPY19L3,GPR146,DDR1,LARGE1,LHX2,VAX2,CRMP1,DAPK1,ARMCX2,DLG4,GPHN,MEX3B,NOP56,GCNT2,GGT5,HPGDS,TDRKH,RAPGEF4,SERP2,GUCY1B1,BACH2,SYNPO,LRRC75A,ITGA7,MPP2,ZC3H12B,PCBP3,TMOD2,ZDHHC8,NLE1,JAKMIP1,SLC25A23,PRKCB,LRRC49,RGS10,KCNIP2,FOXRED2,SATB1,ST8SIA1,ZFP1,LHPP,PHLDB1,ACSBG1,MGRN1,TCF7,TGFBR3,TPD52" Coexpression 16581771-tableS1b Mouse StemCell_Si06_109genes GeneSigDB 6.04E-06 6.99E-02 1.85E-04 1.84E-03 27 73 "FZD9,ANK3,GAS7,OSGIN2,CLU,TJP2,FAM19A5,COL9A1,ARHGAP24,TOX,TIAM2,F3,SCARA3,L1CAM,MMP16,PDGFRA,PPP3CA,PTN,PTPRE,ZDHHC14,RTKN,FAM102A,SLC1A3,SIRT2,EFHD1,ADHFE1,ZMYND8" Coexpression M1733 Cluster P3 of genes with similar expression profiles in peripheral T lymphocytes after FOXP3 [GeneID=50943] loss of function (LOF). MSigDB C2: CGP Curated Gene Sets (v6.0) 6.24E-06 7.22E-02 1.91E-04 1.90E-03 47 160 "ZNF608,SORCS2,CC2D2A,PKP4,DGKD,ATP6V0A1,BAIAP3,CAMK2B,AKAP7,PNKD,CREM,CYBB,HDAC9,SPOCK2,ARMCX4,RHOBTB1,RABGAP1L,OGA,GPD2,GPR34,KAT7,FRMD5,JAK1,MATK,MATN2,MBP,PPM1L,PDE2A,PDE3B,SYTL2,PTPN13,RALGDS,CLIP1,PEAR1,TRA2B,ITSN1,ST8SIA1,DZIP1,FAM81A,SLC15A2,SP4,SAMSN1,SEMA4A,TCF7,ARHGEF12,TGFBR3,ACTR3B" Coexpression M18120 Genes down-regulated in HCT116 cells (colon cancer) by expression of MIR192 or MIR215 [GeneID=406967;406997] at 24 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.32E-06 7.31E-02 1.92E-04 1.91E-03 187 893 "CLK4,CDC7,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PKP4,APC,TMEFF1,ZFYVE28,ASPH,ZBTB10,BARD1,BLM,DST,FUBP1,NIPA1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,RCBTB2,CHM,B4GALT6,FAM189A2,TJP2,DNAJB5,AKAP7,BTF3L4,FAM171B,LRIG1,ARHGEF10,ATRNL1,APPL1,CTH,EDRF1,PHF19,DNAL1,DBT,PITPNC1,COPS7A,FBXO25,KBTBD11,CDON,DYRK1A,PHC2,EEF1A2,IRAK4,PCOLCE2,EML1,EPS8,EXTL2,CLVS1,CORO2B,ST3GAL6,CEP78,TMEM164,MEX3B,SEC23B,SYNCRIP,SEMA4D,SMC2,KHDRBS3,SARAF,ZMYND11,KIAA1841,GATM,FAXC,KIAA1958,KCNMB4,RAB40B,GNAS,PSRC1,GPR19,GPR37,CIT,FAM222A,RASSF8,ARHGAP19,ELOVL5,FAAP20,GAREM2,ZIC5,LRRCC1,USP54,IL6ST,ZNF385B,ITGAV,SLC35G1,KLHL23,KIF5C,KPNA5,LIMS1,MAN2A2,MDM4,MEIS2,MXI1,SFR1,NEK1,NFYA,NUCB2,OPA1,GPR137C,CDK14,ANLN,SNX10,KCTD15,GPSM2,PRIMPOL,MINDY2,EPDR1,MAPK9,VPS13C,UHRF1BP1,PTPRE,RAP1GAP,RADX,TRIM68,RET,RIC8B,RNASEL,RIMKLA,MAP6D1,CNTNAP3,RMI1,HES6,IL17RB,ASRGL1,ZFP30,FERMT1,ANKRD6,CLSTN1,WDR47,KDM4D,SLC9A5,SCMH1,ZFP1,LIMCH1,FAM126B,FNBP1,SP4,EMC1,SS18,TBL1X,TMEM136,SATB2,TCF7,RPGRIP1L,DICER1,SIRT1,RP9P,C18orf54,ZMAT3,DDHD1,TMPO,TPM4,ZNF346,STXBP4,TRPC1,TTPA,UGT8,PITPNB,USP1,BCL2L13,CCDC14,NSD2,XPO1,ZBTB14,ZNF45,LYPD6,REEP1,ZNF184,NT5M,LRP8,STOX2,CAB39L,EPM2A,PHTF2,FBXO36,CERS6,ZNF248,MSRB3,NHSL1,SPATA13" Coexpression M17183 Set 'Oct4 targets': genes upregulated and identified by ChIP on chip as OCT4 [GeneID=5460] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.32E-06 7.31E-02 1.92E-04 1.91E-03 74 290 "ADD3,CDC7,PARG,CDC14B,BMP7,CA4,CACNA2D1,SPAG9,LARGE1,PLAA,FEZ1,IST1,TMEM170A,ZEB2,MYEF2,WDR20,MED12,DPYSL2,DTNA,AASDH,KLHL5,ELAVL2,PIPOX,FGFR1,SORBS1,APOPT1,UFM1,OGA,GAP43,GLDC,TNRC6A,KCNMB4,STMN2,IL1RAPL1,FICD,LINGO1,HAS2,IFI16,KCNN2,MEIS2,NEFM,ENPP2,CDK14,ANKHD1,RASGRF2,RIC8B,CNTNAP3,SALL1,NAXD,SNRPN,SOX2,KDM3A,LHPP,KANK1,DNAJC9,TAL1,FBXW11,KLHL4,TCF4,TCF12,OBSL1,LEFTY2,SLC44A1,PARD3,CHST5,TRPS1,SSBP2,ZKSCAN5,ZIC1,ZIC2,ZIC3,SMARCAD1,URM1,KAT6A" Coexpression 18310505-TableS1 Human StemCell_Matushansky08_886genes GeneSigDB 6.48E-06 7.50E-02 1.97E-04 1.96E-03 151 695 "ASIC1,ADD3,OSBPL1A,ADGRF5,OGT,APAF1,CDK10,ATM,AZGP1,BARD1,CFLAR,GYG2,CA12,DDR1,CALB2,CALM1,SPAG9,PRC1,CDC25B,CLGN,ADGRG1,ZBED5,TJP2,QKI,IQCK,COL4A5,C2CD2,CSF3R,VCAN,CNTNAP2,PPP6R2,ZFYVE16,TBC1D5,DDX46,RABGAP1L,FCF1,EIF1,TUBD1,DMTN,EFS,PIPOX,EXTL2,EYA1,FABP7,DLC1,FHL1,SEC23B,VTI1B,FOXO3,EVL,FOLH1,SORBS1,SMC2,STAG2,GALC,WASF3,BRD8,MSL3,GLUL,OS9,GNAO1,FERMT2,STON1,CIT,GSN,HBA1,MAN1B1,HTR2A,IL6ST,IL11RA,TUBB2B,LAMP2,MAOB,MAT2A,MT1M,NEFM,NNAT,NUCB2,OGG1,PCDH9,PDE3B,PFKFB3,CDK14,SERPINE2,SMOX,EPB41L4B,PPP3CB,PRPSAP2,PTPRD,PEX5,RAD17,RDX,RFX5,RXRA,TMEM156,RMI1,S100B,FNIP1,TRA2B,ZFP30,ITSN1,FAM102A,SH3GL2,DOCK10,SHMT2,AMBRA1,DZIP1,PKNOX2,RAB3GAP1,ZNF334,ELMO2,ATF7IP,LIMCH1,SON,GLT8D1,PEG10,ST5,SEPT8,RGL1,SUPT5H,ARHGEF9,DNAJC9,TACC1,ANKRD12,SLC19A3,SLC35G2,ZMAT3,TIAM1,TNS1,TPD52,CDK20,METTL3,TRO,RUSC1,UBE2H,WIPF1,GUSBP1,ZIC1,ZNF184,ZFAND5,WNK1,PMEPA1,LRP8,CSDE1,ADAMTS9,FIP1L1,TMEM163,ITM2C,RTN4,PHTF2,ZNF248" Coexpression M17123 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing 11q23 rearrangements. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.71E-06 7.76E-02 2.03E-04 2.02E-03 86 351 "ABR,AK2,MRTFA,GAS7,DGKD,ATM,N4BP2L1,ADAM23,ADAM15,BMP7,CAPN3,CAST,CARS,CD81,PPT2,CLTA,QKI,PCYT1B,CS,LRIG1,FEZ1,FAM169A,CYBB,HDAC9,CTIF,KBTBD11,EXOG,TENM1,ELAVL3,RASGRP2,FCGR1A,ST3GAL6,ATP5PD,SEMA4D,GFRA1,GLRB,GLUL,CBX1,GPM6A,GPM6B,GRIK2,NR3C1,HPS5,IDH3A,IL6R,ITGA7,ITGAV,KHK,SMAD1,MBNL1,SHC3,MEF2C,MEIS1,MMP17,MYO6,NFIX,PIK3CD,PKM,FTO,PPP2R5C,PRKCB,MAPK9,PYGM,RET,RGS10,EMID1,ATXN1,GLT8D1,MCF2L2,CAMTA2,NEK4,SUPT5H,TACC1,TAL1,DMXL2,PCDHA3,TPD52L2,CADM1,VIPR2,CLDND1,SF1,PRDM2,EVI5,MPPE1,NELFE,JMJD1C" Coexpression M6241 Top 40 genes from cluster 8 of aculte myeloid leukemia (AML) expression profile; 69% of the samples are FAB M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.79E-06 7.86E-02 2.05E-04 2.03E-03 14 26 "CDC42BPA,ANK1,ABCG2,TSPAN5,OPTN,FECH,MXI1,PBX1,SLC6A8,SNCA,TAL1,ARHGEF12,TNS1,OSBP2" Coexpression M16673 "Top 40 genes from cluster 16 of acute myeloid leukemia (AML) expression profile; 81% of the samples are FAB M5 subtype, 45% have 11q23 abnormalities." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.79E-06 7.86E-02 2.05E-04 2.03E-03 14 26 "C3orf14,TKTL1,AK2,APOC2,ITGA7,KCNN2,MBNL1,PENK,C1orf54,RET,CLSTN2,KCNE5,CADM1,LAMP5" Coexpression M7672 Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]. MSigDB C7: Immunologic Signatures (v6.0) 6.91E-06 8.00E-02 2.08E-04 2.06E-03 55 198 "SPARCL1,OGT,ANK3,CASK,PCDHGB4,RHBDL1,ENTPD2,CBARP,B4GALT6,LHX2,CNTN1,PREPL,C2CD2,CRY2,CLIP3,DCAF8,DGKG,RHOBTB1,ERCC2,EZH1,FGF13,FGFR1,FLNC,DPYSL4,SARAF,DOT1L,CPLX2,LUZP2,GOLGB1,STON1,NXPH2,PTGDR2,HMX1,LSAMP,MEST,MXI1,NF1,PDE3B,GPSM2,PPARA,RAB3A,SCN7A,SCAF8,SH3BGR,SH3BP2,SH3GL2,SEPHS1,FNBP1,ZHX3,CEP68,PLCB1,DNMBP,TIMP4,TJP1,SCG2" Coexpression M1920 Genes forming the macrophage-enriched metabolic network (MEMN) claimed to have a causal relationship with the metabolic syndrom traits. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.02E-06 8.12E-02 2.10E-04 2.09E-03 243 1210 "ABR,NDRG2,ADCY6,CDC7,PTCHD1,OSBPL8,SRPX,TRMT9B,FAM131A,CACHD1,SHTN1,ARHGDIA,ARRB2,ASGR1,DYNLL1,ATP1A3,ATP6V0A1,DOCK11,BACH1,BCS1L,NRP2,SYNJ1,C1QC,RAB29,WASF1,IL33,CH25H,KYAT1,FMNL3,CERS5,CD86,CD38,ENTPD2,CDC42,LARGE1,NUMBL,MS4A7,B4GALT6,ARHGAP22,LY86,HOMER3,SLC4A7,GAL3ST1,TBPL1,ZNF521,CNRIP1,ABCG1,CSF1R,CSF2RA,CSF3R,LRIG1,OSBPL3,VCAN,FAM131B,CYBB,MYADM,SIRPA,ARMCX2,HEPH,FBXO25,CCDC3,DLG3,SHANK1,DOCK2,GNE,TOM1,ABCC5,EBI3,ABI2,PLXNC1,RASA4,CERCAM,EML1,OLIG2,PLEKHO1,EPB41,EPB41L2,EPS8,IGSF6,SPEG,TLR7,FAM198B,FABP7,RPS6KC1,TBC1D16,PTK2B,TUBB4A,TAOK3,FCGR1A,FCGR3A,ACTL6B,TMEM164,FHL1,EVL,SEMA4D,ANKFY1,HVCN1,AK8,FAM49B,SDCBP2,HBS1L,IQGAP2,MTHFD2,ACSS1,GATM,SESN1,GGT5,GJB1,HPGDS,STARD3,PSRC1,GPM6B,SPACA9,GSN,SLC2A6,RASSF8,PADI2,NCKAP1L,SYNPO,ICA1,IRF8,IFI16,LRRC25,IL11RA,ZNF385B,KCNN2,STXBP5,L1CAM,LAMA2,LAMP2,LMO2,PIK3AP1,MAP4,MATN2,MDFI,TM6SF1,PPM1L,CPNE9,CCDC80,MSR1,NRBP2,MT3,LAYN,MYO5A,TCEAL5,NAP1L1,P2RY13,NCF2,NFE2L2,SLC11A2,OLR1,TREM2,CDK18,PDE3B,PFKP,PKM,FAM216A,SMOX,SLC25A23,PLTP,PLXNB3,PMP22,LRP12,SPATA6,PILRA,RASGEF1B,MAPK7,PRODH,GDPD1,PSD,CYBC1,SPDL1,PTPN13,PTPRE,PTPRO,RIPOR1,RAB3IL1,PLEKHB2,RALGDS,C1orf54,SUSD4,RGS10,KCTD17,SLC25A36,RNH1,LGI2,TMEM206,RPE65,MCMBP,PRR5L,ACER3,RPS6KA2,LGR4,PTGR2,WLS,SEMA6D,RASA3,SH3BP2,DOCK10,SYBU,SLC4A3,SLC6A8,SLC8A1,SLC11A1,TRERF1,UNC5B,SPTAN1,ITPRID2,SAMSN1,SSTR2,EPB41L3,RGL1,PHLDB1,STXBP1,NECAB1,SYP,SLC37A2,ZFP90,TPCN2,OBSL1,AKNA,ARHGAP9,ATP13A2,HEY1,TLR4,TPD52,NPL,TPM3,RFTN2,CADM1,BCL2L13,VAV1,LAT2,NPDC1,AMZ1,SEMA3B,SNX27,ITM2C,PLD4,DOCK8,CERS6,SLC39A12,FRMD6" Coexpression M8513 Genes up-regulated in the normal-like subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.09E-06 8.20E-02 2.12E-04 2.10E-03 110 476 "ADD3,ADGRF5,SPARCL1,SRPX,BBOX1,BIN1,ANK2,DST,BTK,IL33,CH25H,RUNX1T1,CD38,CDO1,FOXN3,CHRNB2,NRXN1,NRXN2,CLU,CRY2,SNCAIP,CSF2RA,PPP1R16B,RIPOR2,GIT2,ELMO1,CHRDL1,DMD,DOCK2,DTNB,EDN3,RASA4,AASS,PLEKHO1,RASGRP2,EZH1,ABCA8,EFEMP1,FHL1,FOLR2,SORBS1,NSG1,FYB1,FYN,CHL1,ADAM28,GGT5,LYVE1,FAM107A,WIF1,IRF8,IFI16,IGF1,IL6R,ITGA7,KCND3,KIT,LAMA2,PACRG,MATK,MATN2,MBP,MEF2C,MGAT3,MT1M,NAP1L2,NPR2,NTRK2,OXTR,PCSK5,PDE2A,PDGFRA,ENPP2,CYTL1,PIK3CD,PIK3R1,PLCB2,FXYD1,PLTP,POU6F1,LRRN3,PPP3CC,PRKCB,RELN,PTN,CCDC102B,BAALC,S100B,SATB1,SELL,DOCK10,ST6GAL1,SLA,CCDC88A,SLC12A4,VAMP1,ROBO3,TCF4,ZEB1,SYNE1,TF,TGFBR3,TIE1,TMOD1,TNFRSF1B,LILRA4,FLRT2,WIPF1,ITM2C,NLRP3" Coexpression M2004 Genes with intermediate-CpG-density (ICP) promoters bearing histone H3 K4 trimethylation mark (H3K4me3) in embryonic stem cells (ES). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.12E-06 8.24E-02 2.12E-04 2.11E-03 155 718 "SYN3,NCKAP5,PLEKHG5,ADD3,NME5,C1QTNF1,ABCD2,AMH,ANK2,ANK3,ATP6V1G2,TTLL9,BCL2L2,ZNF599,LDHD,SYNJ2,CACNG1,CD38,CHM,NRXN1,TPP1,STOML1,AKAP7,PCYT1B,FAM149A,AKAP6,COL4A5,SUMF2,SMARCAL1,RTTN,CTNND1,DCAF4,KIAA0408,KATNAL2,TCAF1,DGKB,ELMO1,MED24,ALKBH8,SACS,SV2A,SRGAP3,DLG4,CD99L2,SLC12A6,FIS1,KLHL5,FAM13A,MBNL2,AASS,LPAR6,ETV1,CEND1,ABCA8,FAM198B,SCML2,TOMM40L,SLC9B2,FGR,IP6K2,SYT3,TRIM16,TPPP3,BRSK1,TVP23A,MEGF10,TRAF3IP2,GHDC,GAP43,ALDH1L1,ZNF276,PLPP7,SPACA9,GRIK5,CELF3,CPT1C,HSPA1L,ATCAY,KCNA4,KCND1,LAMA2,LIFR,SYTL4,ASPRV1,EFHB,MT3,LINC00672,NAP1L2,RCOR2,IDNK,P2RX7,PBX1,PCSK1,GNG2,PGAM2,GDAP1L1,SERPINI1,C11orf49,PPP2R5C,HYDIN,WBP1L,ZIK1,RIPOR1,PPP2R3C,SH3TC2,SLC25A41,RFX5,ARMH4,FBXW7,ADAL,RYR1,TRAPPC13,DGLUCY,CSRNP3,HOGA1,TRIM46,SH3BGR,YPEL4,SLC11A1,MTERF2,SPHKAP,INTS9,FAIM2,TSNAXIP1,SPP1,PBLD,ZC4H2,ST5,ADHFE1,ARHGEF9,SYT1,SYT5,EHBP1,TPCN2,TRIM2,DOCK9,GPRIN3,TEK,ACTR6,SMUG1,ZMYND8,RFTN2,ZKSCAN5,DNAJC12,FLRT1,MICAL1,CFAP52,FTSJ1,DNALI1,MDH1B,C12orf4,TMEM63C,NHSL1,SSPN,SLC4A10" Coexpression M1113 Up-regulated genes from the set C (Fig. 5a): specific to cells expressing AF4-MLL [GeneID=4299;4297] fusion protein alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.16E-06 8.28E-02 2.13E-04 2.11E-03 49 170 "RBM10,LCORL,DPY19L3,CLDN10,SRSF11,FOXN3,FAM149A,BTF3L4,LRIG1,GPSM1,TOMM20,B3GAT3,ZC3H11A,USP3,SLC12A6,PDCD6IP,E2F6,KCTD3,SPEG,RASL12,PDLIM5,TPK1,B4GALNT1,MAP4K5,GPR45,KLF12,NEUROD1,SLC11A2,PDE1C,PLEC,PTHLH,PTPRD,RAB3IL1,FAT4,RFX3,RPS20,TNFRSF19,PUF60,FNDC3A,PDZD2,TSNAXIP1,ERBIN,TCF4,TCF7,ZIC3,ZBTB38,PPP1R3F,FAM13C,NETO2" Coexpression M3134 Up-regulated genes constituting the molecular signature of Burkitt 's lymphoma. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.22E-06 8.35E-02 2.14E-04 2.13E-03 19 43 "APBB2,BMP7,WASF1,PTBP2,NSG1,BACH2,TUBB2B,NASP,SUGCT,FHOD3,SMARCA4,SOX11,RAP1GAP2,SSBP2,TUBB2A,UCHL1,PRDM10,TUBA1A,HNRNPA3" Coexpression 18698033-tableS1-ESR1 Human Breast_Desmedt08_469genes_ESR1_Module GeneSigDB 7.28E-06 8.42E-02 2.15E-04 2.14E-03 105 450 "TTYH1,SERPINA3,ABAT,ABCF1,FZD9,NME5,SPOP,ALCAM,SYT13,BIN1,APBB2,BCAS1,PROM1,CA12,CACNG1,CBS,LRBA,REPS2,CLGN,CHI3L2,EPS15L1,RAB26,COL9A3,CP,LRIG1,KIAA0040,CTNND2,NOS1AP,KIAA0753,SACS,RCAN1,EEF1A2,EGR3,ERBB4,NCALD,FABP7,ZMYND10,UBE2E3,EVL,KHDRBS3,WASF3,GPR162,GFRA1,GLRB,GPM6B,GPR37,GRIA2,PTPRT,FAM107A,GUCY1A1,ELOVL5,IL6ST,KCNJ3,MARK1,MDFI,N6AMT1,PCDH8,RETREG1,SIDT1,WDR25,ELOVL2,PTPN13,PTPRZ1,PTX3,QDPR,ROGDI,RIC8B,EXD2,UEVLD,RYR1,SATB1,FNIP1,FAM102A,KIF16B,SYBU,ABLIM3,SEPHS1,CDK5RAP3,SLC22A4,SOX10,SOX11,CLUAP1,BEX1,NEK4,KLHL7,ABCC8,ASTN2,TRIM2,TNNT1,TP53BP2,TPD52,CDK20,ZMYND8,SSBP2,UCHL1,UGT8,DNAJC12,VLDLR,SLC13A3,ZIC1,DNALI1,SLC38A1,HRASLS,ACTR3B,IFT88" Coexpression 11731795-SuppTable1 Human Lymphoma_Armstrong02_100genes_UnderExpressed GeneSigDB 7.46E-06 8.63E-02 2.20E-04 2.19E-03 30 86 "APP,DDR1,LARGE1,MAGED1,AKAP12,DBN1,SMG7,E2F5,FGFR1,GAB1,HBS1L,IFI16,LIG4,SMAD1,CD200,NPY,SCHIP1,PRKCB,PTK2,RBBP6,ZNF821,SMARCA4,ZNF423,SPTAN1,CEP68,RGL1,TCF4,TCF7L2,PARD3,ZNF45" Coexpression M8215 Genes in the expression cluster 'HSC and Progenitors Shared': up-regulated in hematopoietic stem cells (HSC) and progenitors from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.86E-06 9.09E-02 2.31E-04 2.30E-03 148 681 "KIAA1211,SNX30,PLA2G6,PITPNM2,USP28,PKP4,NT5C3B,ASCL1,ZBTB10,LDHD,BSN,CAMK2A,USP2,CBFA2T2,ARHGEF2,DCLK1,ZMYM4,ADGRG1,FADS2,RAB26,AKAP6,SLC4A8,ZNF521,CNRIP1,C2CD2,CREM,SH2B1,SEC24C,OSBPL3,ARHGAP32,FGFR1OP2,EARS2,RASSF2,DAPK1,SPOCK2,ARMCX2,JAKMIP2,HP1BP3,KIAA0753,MAGI2,RHOBTB1,DLG3,PDCD6IP,DNM1L,EDIL3,ABI2,EML1,EN2,SLC43A2,CEND1,TBC1D16,TAOK3,PRKAG2,SEC23B,AGAP2,TMEM175,STAMBP,TPK1,KHDRBS3,NSG1,SARAF,TPPP3,MEGF10,ILDR2,NEK6,SESN1,CBX1,GPR12,SPACA9,PRDM5,KIF3A,CLASRP,KLF12,HSPA1L,FAAP20,KCNC1,KCND3,GPR62,KIT,SYTL4,SMAD1,SMAD9,MAN2A2,MEF2C,MEIS1,MGAT3,MN1,CCDC80,PTOV1,MDGA1,MYCN,NAP1L3,NCAM2,NDP,SFR1,NELL1,NRGN,SMIM11A,NTRK3,OCRL,ZNF827,PRTG,SEMA5B,EPB41L4B,PPP2R2C,MTMR10,NKAIN1,PLEKHB2,RET,RGS3,SLC25A36,TMLHE,PLPPR3,SCN8A,ASRGL1,DHX30,TET1,TNIK,CAND2,SPART,LHPP,THSD1,MPRIP,STXBP1,SYT11,PRRC2C,C3orf70,KAZN,FBXW11,CRTC1,TEK,DICER1,NPL,TPM3,DCBLD1,TTPA,FAM155A,MTCH1,PLPPR2,VAV2,MEAF6,LGI4,LYPD6,FSTL5,DHX33,STOX2,GOPC,ACTR3B" Coexpression M6765 Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.96E-06 9.21E-02 2.34E-04 2.32E-03 43 143 "ADD1,ADD3,ALDH4A1,BCHE,GPR146,AP1M1,CACNA1E,CSF1R,PPP6R2,HDAC9,PLEKHM1,C2CD2L,SV2B,DLG2,CPEB2,DPYSL2,DYRK1A,SNX29,FCGRT,TMEM175,ACSS1,RAPGEF4,GSN,KNDC1,KCNJ16,PDE2A,PDE4A,PLCB2,RPS6KA2,TMEM200C,GALNT10,PPM1E,ST6GAL1,SCMH1,SULF2,VAMP1,SYNE1,TRPM2,TSC2,SH3GLB2,KCNAB1,MVB12B,ADAMTS10" Coexpression M15476 Genes up-regulated in primary adipocytes compared to preadipocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.11E-06 9.39E-02 2.36E-04 2.35E-03 27 74 "MTUS1,AGT,AMT,MAP4K3,SPTBN4,ATP2B2,SLC24A2,DGKG,ECM2,FABP7,C1orf61,CAP2,ATP8A2,MSTN,GLUL,GPD1,KCNH2,PFKFB3,PLCD1,PLIN1,FXYD1,MASP1,PTPRZ1,DPF2,RXRA,GZF1,LRP8" Coexpression M8436 Genes up-regulated in CD8 T cells: stem cell memory versus central memory. MSigDB C7: Immunologic Signatures (v6.0) 8.13E-06 9.40E-02 2.36E-04 2.35E-03 55 199 "ADORA3,BEND6,AMPH,LRFN1,TMEFF1,CDH8,CDH10,LARGE1,CHRNB2,COG1,FBXO7,TJP2,SULT4A1,SCRN1,GIT2,PLPPR4,DMD,EBF1,AASS,PLEKHO1,LRRC23,EYA1,EFEMP1,TBR1,NRG3,MEGF11,GABRA4,PPARGC1A,ZNF496,ARHGAP36,DHX35,INSM1,NBL1,CAMKV,FXYD1,PCDH18,PRKCZ,RAB5B,SUSD4,SCN2A,SCN2B,SMTN,ARC,SEMA4A,MCF2L,GPRIN3,CSMD1,PIK3R5,FNDC5,CFAP52,ATP6V0E2,NDRG4,INTS3,HPS4,ST8SIA2" Coexpression M10033 Genes down-regulated in macrophages: control versus colorectal adenocarcinoma conditioned. MSigDB C7: Immunologic Signatures (v6.0) 8.13E-06 9.40E-02 2.36E-04 2.35E-03 55 199 "AS3MT,USP28,ARNTL,CAMK2A,CAMK2B,CAMK2G,AIFM1,NEURL1,FEZ2,SPOCK2,PITPNC1,GUCD1,DMD,ABCC9,E2F6,RCAN2,SPEG,DUSP27,ECSIT,ST3GAL6,PDLIM5,ALDH1L1,FERMT2,RAPGEF1,HSPA1L,ITGA7,KCNA4,IPO5,KTN1,MEF2C,PPM1L,PDZRN4,PPM1B,PPP1R1A,PPP3CA,PYGM,USP47,TMEM206,RYR1,SATB1,SCN4B,ZFP2,URGCP,SMARCD3,TMCC1,TEX2,KIF1B,ADHFE1,POPDC3,SYNPO2,AMOT,REEP1,CSDE1,PHTF2,KLHDC1" Coexpression M6356 Genes up-regulated in gamma delta T cells stimulated by phorbol myristate acetate and ionomycin [PubChem=4792;3733]: Vd1 versus Vd2. MSigDB C7: Immunologic Signatures (v6.0) 8.13E-06 9.40E-02 2.36E-04 2.35E-03 55 199 "METAP1D,AGT,CDK13,CAMK2D,TJP2,MAGED1,ARMCX2,ANKRD46,HIPK3,EGR3,C8orf37,PIPOX,RASL12,NSRP1,CORO2B,RACK1,SLC9B2,FYN,GAD1,GLRB,GPM6B,KIF3A,SLC2A6,CREG2,LAMP2,MYH3,MYO7A,PCBP3,ENPP2,SMOX,MBOAT7,MAPK8,SLC26A11,QRICH1,ARID4A,KIF7,SLC25A36,SEC14L1,SH3GL3,ZNF667,KIF1B,NEK4,ZFR2,SYPL1,ZEB1,TCF12,ITGB3BP,BHLHB9,TPD52,ZMYND8,TTC3,ATP6V0E2,GDPD5,RNF170,FXR1" Coexpression 17761679-Table1 Mouse Pancreas_Keller07_85genes GeneSigDB 8.17E-06 9.45E-02 2.37E-04 2.35E-03 26 70 "PLA2G6,SYT13,ATP6V0A1,CHM,ST18,FYN,PCLO,HMGCR,NEGR1,ICA1,MYT1,NEUROD1,NKX2-2,SNTG1,PAX6,PBX1,PCSK1,PCSK2,PDE4B,PPP2R2C,HES6,RPH3A,SYT11,ABCC8,SYN1,TOM1L2" Coexpression M470 Genes down-regulated in RAW264.7 cells (macrophage): control versus stimulated with IFN-b. MSigDB C7: Immunologic Signatures (v6.0) 8.26E-06 9.56E-02 2.39E-04 2.37E-03 36 112 "TTYH1,ACTN2,ADRA1D,LRFN2,SLC44A5,PCDH19,BCAR3,ANK3,BAIAP3,NGB,MYRIP,SEC31B,AATK,TMCC2,FHL1,ATP13A4,DPYSL4,KIRREL3,LYVE1,PCLO,PLPP7,SCRG1,INSYN2,NLGN3,PCDH18,MAPK4,MRAP2,RTN1,SLC1A3,SLC20A2,KDM4B,PBLD,CNTN2,SLC35G2,GPR161,FZD3" Coexpression M2128 Genes up-regulated in growing IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.79E-06 1.02E-01 2.54E-04 2.52E-03 64 243 "CDC7,CDC42BPA,VAT1L,B3GALT2,CA12,RUNX1T1,LDB2,CDC25B,JAM2,SLIT2,NRXN3,CLU,TOX,TSPAN5,LRRC17,FAM198B,FGF1,SCARA3,FOXM1,SMC2,GPM6B,PSIP1,ADAMTS6,HAS2,IFI16,KCNK2,KCNMA1,KCNN2,LSAMP,MATN2,MEIS2,MEST,CCDC80,NASP,ALDH1L2,NRGN,CLDN11,OXTR,CNTN3,PSAT1,ZFHX4-AS1,ELOVL2,PTN,PTX3,RBBP8,UBR7,RGS4,BAALC,PEAR1,DOCK10,SHMT2,FBXO11,SLC14A1,DNAJC9,ANKRD28,ITGB3BP,CBX5,TMPO,TTC3,USP1,NSD2,NAV2,CERS6,DPF3" Coexpression M11504 "Genes down-regulated in prostate cancer vs benign prostate tissue, based on a meta-analysis of five gene expression profiling studies." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.17E-06 1.06E-01 2.64E-04 2.62E-03 18 40 "DST,SGCE,CALM1,CLU,AKAP12,SCRN1,FHL1,GATM,GSN,MEIS1,MEIS2,PMP22,SMTN,SPART,ST5,TACC1,DAAM2,TPM2" Coexpression 19276370-SuppTable1 Human StemCell_Hasselblatt_53genes GeneSigDB 9.35E-06 1.08E-01 2.68E-04 2.67E-03 21 51 "ACADM,SPARCL1,CDC14B,CACNA1A,SRSF11,CNTNAP2,NPTN,WIF1,HMGB1,GABARAPL2,IL6ST,PLEKHB2,SFPQ,LMBRD1,AJAP1,TAC1,OBSL1,ZNF106,CBX5,SF1,FXR1" Coexpression M9253 Genes down-regulated in dendritic cells: hydrogen peroxide [PubChem=784] versus diphenyleneiodonium (DPI) [PubChem=2733504]. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ACADM,AQP6,BBS2,GPR146,CFLAR,MTMR2,ASIC3,KMT2C,NIPBL,SLC25A27,ABCG1,GPRASP1,KBTBD11,NR1D2,ATN1,RASGRP1,EGR3,CALCRL,ATP8A1,FOXO3,EVL,HVCN1,OGA,ACSS1,NR3C1,PPM1L,MIR4697HG,PFKFB2,ZNF655,RAD52,RASGRF2,ZDHHC14,ZYG11B,TMEM206,PCMTD2,ZNF354C,SATB1,SELL,ATF7IP,TET1,TMCC1,MYCBP2,ERBIN,CAMSAP2,ALG1,KIAA0930,TCF7,RUNDC3B,AMACR,TSC1,PDIA2,TBC1D15,REEP1,PPP1R3F,JMJD1C" Coexpression M312 Genes down-regulated in primary bronchial epithelial cells stimulated with: IL17A [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "CPNE2,FMNL2,OSBPL1A,LRCH2,MAP4K3,PHF12,PDE8B,CCAR2,BTRC,SCARB1,ARHGEF10,CTNND2,HDAC9,LONRF1,DAPK1,SV2B,DLG3,DLG4,ABI2,SLC43A2,APC2,CHST15,DCLK2,KCNJ5,PPM1L,PTOV1,LAYN,PALM,NLGN3,CAMKV,PLCL1,MED1,CEP97,ELP2,RYR1,FOXRED2,ATXN2,SCN8A,KIF21A,LGI3,TET1,ZNF667,SMARCC2,IFT122,THSD1,TBCEL,TBX15,TCF4,ZEB1,PSD3,R3HDM1,SEZ6L,UCHL1,FAM13C,NLRP3" Coexpression M7553 Genes up-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ADD3,SNX30,KIDINS220,GPRASP2,APC,VAT1L,CADPS,MTMR9,MPDZ,SOCS6,AKAP6,CREM,MYADM,GSDME,RAB39B,DNAJB6,FSD1L,OPTN,LINC00654,SYT17,FREM1,SPIN1,IFI16,KIF5A,NCOA7,LSAMP,TAGLN3,NAP1L2,NAP1L3,ABCB1,PIK3R1,LRRN3,PRKACB,GDPD1,PTPRH,TUG1,ZNF793,EXD2,CLIP1,RTN1,WDR47,NAPB,BEX1,CLASP2,SSTR2,SYT1,PCDHB10,BEX4,ZNF711,ZNF540,REEP1,ZNF177,LOC100506497,AMN1,CASC15" Coexpression M8056 Genes down-regulated in plasmacytoid dendritic cells (6 days after knockout): wildtype versus TCF4 [GeneID=6925] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "GRAMD1B,ABCD2,FGD2,APOC2,MIER1,NCOA1,ATP2B1,BACH1,GPR146,SOCS6,ARHGAP22,TPP1,ARHGEF6,ABCG1,PHF14,PUM1,PLEKHM1,RABGAP1L,PLEKHO1,RCSD1,FCGRT,BAIAP2,PDLIM5,FYN,MSL3,GPR34,DDX19B,NIM1K,TM6SF1,OPHN1,P2RX7,PURG,PPP3CA,RAB3IL1,ZDHHC14,WLS,CHD9,R3HDM2,GKAP1,SCN3B,UHRF1BP1L,SULF2,FGD4,TCF12,TMEM9,TPD52,SSBP2,WIPF1,AGMO,WNK1,MAP3K12,ITM2C,RTN4,ADAMTS10,FXR1" Coexpression M9657 Genes down-regulated in CD4 [GeneID=920] T helper cells (60h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ACLY,ANK3,PPFIA4,MTMR9,BMPR1B,CAMK2A,CANX,CD86,LRBA,B4GALT6,RAB33A,MAP4K4,CNGA3,RNF14,AATK,DCC,DLG4,DNM1L,ST8SIA3,SH3GLB1,ELAVL4,ZIC4,ATP6V1H,ST6GALNAC3,STAG2,GABRA1,CPLX1,TUBA8,SRCAP,TXNL4A,PTPN5,IDH3B,ITGA7,KCNJ11,MT3,MX1,SERPINE2,FAM216A,PRKAR1B,BCAS3,ZYG11B,AP1AR,SLC22A4,SOX11,TBX15,SLC44A1,NPL,TSC1,UBE3A,LGI4,MKRN3,ZSCAN26,SLC30A3,TUBA1A,FRMD6" Coexpression M4297 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] low T cells at. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ADD2,PLA2G6,SPARCL1,BCAR3,LRFN1,PTCH2,AZGP1,LURAP1,CHRM1,MS4A7,CPNE6,SLC35F1,GPRASP1,JAKMIP2,ZEB2,TMCC2,SLC29A4,EGFR,SIRPB1,TUBB4A,SCML2,C2orf88,ADAM28,GNAL,FERMT2,GPR12,TMEM121B,PCLO,TMEM179,CELF3,KCNA2,KCNH1,MYT1,NPY,NTRK2,PLCL1,IRX1,PRKCG,SLC26A11,PLPPR1,REV3L,STX1B,EPN2,ARHGEF40,SYN1,SYP,PCDHB7,ZFPM2,CRB1,TGFBR3,PRMT8,FSTL5,ADAMTS9,NLRP3,IFT88" Coexpression M8465 Genes down-regulated in activated CD4 [GeneID=920] T cells: wildtype versus over-expressing MIR17 [GeneID=406952]. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ACADM,AXIN2,HHATL,KLHL13,CARNS1,FAM131A,ATP1A2,ARHGEF25,CFL2,DRD1,SIDT2,RGS17,RCAN2,DLC1,CAP2,GABRB1,NKX6-2,TMEM8B,STARD10,MYOZ2,PPARGC1A,GNAO1,BVES,GUCY1A1,VSIG4,NKD1,KCNJ3,LAMA2,MAOB,CCSER2,PLXNB1,ING3,SEPT4,PPARA,SYTL2,PYGM,ZYG11B,ARMH4,ABLIM3,SLN,LIMCH1,CABCOCO1,ADHFE1,ABCC8,RHBDL3,EHBP1,WSCD1,THRA,TNNT1,SYNPO2,FNDC5,NTSR2,DPYSL5,TMEM163,FRMD6" Coexpression M4978 Genes up-regulated in comparison of plasmacytoid dendritic cells (pDC) from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 9.54E-06 1.10E-01 2.69E-04 2.67E-03 55 200 "ADRA1B,LGR5,MADD,ASIC3,CLCN4,NRXN2,SPOCK3,SEZ6L2,ETV1,CEND1,ZIC4,EFEMP1,PRELID3A,TDRKH,STON1,GRB10,CACFD1,ADAMTS8,PTGDR2,IGFBP1,BRINP3,KCNJ16,KHK,L1CAM,NKX2-2,PALM,PCSK5,ZFYVE21,KCTD15,EPB41L4B,DIRAS2,PTPRD,ATG16L1,RGS4,SETD5,KCNIP2,FAM182A,MAPK12,SCN2A,SCN2B,ZFP2,SH3GL3,SLC8A2,MYH15,SOX10,APOM,PHLDB1,SYT5,TACR1,SMG6,TF,ZKSCAN5,TUBB1,NDRG4,NAV2" Coexpression M2781 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 9.66E-06 1.12E-01 2.71E-04 2.70E-03 43 144 "NDRG2,GAS7,API5,COL9A3,TCEAL2,CREM,CLIP3,EEF1A2,ETV1,CHL1,TRAF3IP2,CAB39,GPR162,PPARGC1A,STON1,PADI2,KCNJ16,ARHGAP12,MAOB,GPR88,PCDH8,PDE4B,PRPH,WDR25,PID1,C1orf54,PNMA8A,RXRG,KANSL3,EFHD1,SOX2,DOK5,NMNAT2,ZNF423,LMO3,TRIM2,CDH22,TNNT1,TRPS1,SSBP2,DNAJC12,SLC17A6,SSPN" Coexpression 15902281-TableS1e Human Leukemia_Schoch05_1374genes GeneSigDB 1.01E-05 1.17E-01 2.82E-04 2.80E-03 129 581 "ADCY2,ADRA1B,ADRB2,NME5,C1QTNF3,SEMA6A,APC,PDE8B,ALDH7A1,CAMK2A,TRIM41,CANX,CAST,CCNH,CDH10,CDH18,CDO1,CNOT8,CLTB,NIPBL,NRG2,CRHBP,HAPLN1,RNF14,SNCAIP,CSF1R,CSNK1G3,VCAN,FAM169A,CTNND2,ZFYVE16,MATR3,MAML1,DBN1,JAKMIP2,KLHL3,DDX46,DOCK2,DRD1,EDIL3,DCTN4,CDKL3,REEP2,RACK1,FER,FGF1,POLK,FYB1,MEGF10,GABRA1,GABRG2,IQGAP2,ERAP1,CPLX2,GDF9,GHR,BRD8,TCERG1,TPPP,GRIA1,NR3C1,KIF3A,ADAMTS6,SYNPO,HMGCR,IL6ST,KCNN2,KIF2A,LIFR,MEF2C,PCDHGC3,PCSK1,PDE4D,PIK3R1,RETREG1,IRX1,PCDHB17P,MAPK9,ANKHD1,SPDL1,RAD17,SH3TC2,KCNIP1,ZNF354C,FNIP1,ZFP2,GALNT10,ABLIM3,SLC1A3,SLC6A7,SLC12A2,SLC22A4,SNCB,PDZD2,BDP1,ARHGAP26,ATP10B,ERBIN,SEPT8,TAF9,WWC1,FBXW11,ACSL6,TCF7,PCDHGC5,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA1,PCDHB15,PCDHB10,PCDHB9,PCDHB7,PCDHB6,PCDHB4,PCDHB3,NSD1,PCDHAC2,PCDHA6,PCDHA5,PCDHA3,PCDHA2,THBS4,TRIO,AMACR,SSBP2,XRCC4,TIGD6" Coexpression M7002 Genes down-regulated in B lymphocytes: ZFX [GeneID=7543] knockout versus wildtype cells stimulated by anti-IgM for 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.01E-05 1.17E-01 2.82E-04 2.80E-03 46 158 "ACTN2,USP28,SLC25A27,AKAP5,LRIG1,KBTBD11,SNX29,RASGRP1,PLEKHA1,LRRC23,SLC43A2,CHST15,EVL,ZMAT1,ACSS1,TDRKH,RAPGEF4,BACH2,HECTD2,MBP,NTRK3,PKD1,PLCB2,JAKMIP1,SIDT1,EML5,WLS,SELL,ST6GAL1,ST8SIA1,DZIP1,TET1,MBD5,KIF1B,CEP68,MGRN1,TCF7,SYNE1,TGFBR3,KAT6B,SSBP2,TTC3,TOM1L2,MAP3K12,MPPE1,KLHDC1" Coexpression M6877 Genes up-regulated during B lymphocyte differentiation: large pre-B II versus VPREB1+ [GeneID=7441] pre-B Il. MSigDB C7: Immunologic Signatures (v6.0) 1.02E-05 1.18E-01 2.83E-04 2.81E-03 49 172 "CPNE2,NCKAP5,ADD3,SNX30,MTA3,OSBPL1A,DOCK11,LARGE1,ADGRG1,ATRNL1,HDAC4,ARMCX4,DNAJC6,ZEB2,HP1BP3,CALCRL,PAN3,EZH1,PRKAG2,ARPP21,USP19,TOX3,TDRKH,ATG4C,ACOT7,HMGCR,KIT,STXBP5,LIMS1,NCOA7,CD200,CAMKV,PIK3CD,SNX10,OXR1,ZDHHC14,RNASEL,ATP8B4,HSPA4L,CHD9,SLC12A2,TACC1,TCF7L2,CYB561A3,TGFBR3,TPD52,CDK20,PLD4,DOCK8" Coexpression 18757322-TableS3 Human Breast_Creighton08_584genes GeneSigDB 1.05E-05 1.22E-01 2.92E-04 2.90E-03 110 480 "ADD3,MTUS1,OSBPL1A,NME5,ANK3,PKP4,APAF1,APBB2,ZBTB10,ALDH7A1,N4BP2L1,RAB29,CAMK2G,CAST,REPS2,LARGE1,RCBTB2,FOXN3,CNOT8,TPP1,QKI,LETMD1,COL9A3,LRIG1,FEZ1,DZIP3,CTNND1,ARHGAP32,KIAA0513,TBC1D5,RHOBTB1,FRY,SIDT2,OPTN,ING4,ERBB4,RRAGB,GMPR2,ARMCX1,SH3YL1,ATP8A1,CHST15,FGF13,FHL1,IP6K2,TPK1,GALC,ATP8A2,INPP5K,BRD8,GLUL,RAB40B,GOLGB1,STON1,RAPGEF4,NR3C1,GABARAPL2,HMGCL,HNMT,IL6ST,JAK1,KCNMA1,KCNN2,LMO2,MATN2,MXI1,NELL2,PAH,PBX1,SNX10,RETREG1,PLCL1,PMP22,RETREG2,DIRAS2,PTCH1,ELOVL2,PTPN13,ACSS3,ARID4A,RFX5,EXD2,PCMTD2,NEK11,SLC1A2,EFHD1,SMARCE1,LMBRD1,SOX3,SPATA7,KDM3A,GLT8D1,CDK19,ZNF302,CEP68,TACC1,TRIM2,PSD3,SIRT1,BEX4,SGK3,CADM1,TBC1D15,WIPF1,ZNF32,RNF103,PLSCR4,MARCH8,UBE3B,FXR1" Coexpression 17483311-SuppTable1 Human Brain_Beier07_383genes GeneSigDB 1.06E-05 1.22E-01 2.93E-04 2.92E-03 69 269 "SLITRK1,LRCH2,PARG,RGS9,BCL2L2,CFLAR,PROM1,SYNJ2,ARHGEF7,IL33,CACNA1A,CAMK2G,SOCS6,STOML1,AKAP7,COL9A3,RTTN,ST18,ARHGAP24,RABGAP1L,ABCC9,CNNM1,FAM13A,MRO,HSD17B14,FGFR3,MPP6,SALL3,GATM,GGT7,MALT1,RAB30,ZNF638,LNX1,RAPGEF1,BTN2A1,FAM107A,ATOH8,HNMT,INPP1,PACRG,MBP,BLOC1S2,NELL2,NOS1,SLC11A2,GPR88,PIRT,SSH1,PPARA,MAPK9,SNRK,PTCH1,PID1,RLBP1,FHOD3,KIF13A,FNBP1,MESP1,ROBO3,KIAA0930,AZIN2,OBSL1,SYNPO2,RUSC1,SSBP2,ZIC1,TCEAL7,PPP1R3F" Coexpression M361 Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 3h. MSigDB C7: Immunologic Signatures (v6.0) 1.08E-05 1.25E-01 2.98E-04 2.96E-03 47 163 "CARNS1,B3GALT2,SLC25A27,C2CD2,CRY2,RIPOR2,DYRK1A,HIPK3,PHF20L1,GMPR2,CAMSAP1,GABRA4,SYT17,TNRC6A,ATG4C,KLF12,NRBP2,MTR,PDE4B,PDE4D,PKD1,DRAM2,ZIK1,ZDHHC4,RPRD1A,EXD2,FBXW7,AP1AR,FAM102A,SPP1,ARHGAP26,TROVE2,STAU1,ANKRD28,TCF7,USP22,SIK3,TGFBR3,CLDND1,RICTOR,SF1,SPHK2,PARP6,RNF103,RTN4,NUP214,CERS6" Coexpression M5765 Genes down-regulated in comparison of untreated macrophages versus those treated with IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.08E-05 1.25E-01 2.98E-04 2.96E-03 54 196 "ALK,AZGP1,CA8,RHBDL1,LDB2,ENTPD2,NRXN2,AKAP6,CABP1,COL9A3,SNCAIP,FAM169A,DCAF8,ARMCX4,EDN3,EEF1A2,AASS,DMTN,CPLX2,GGT5,TUBA1C,STMN2,HRH3,ATXN2L,HNF4G,C2orf72,KCNC1,KIT,MEIS2,SAMD14,MYO9A,NHLH1,PTK2,SLC6A15,MORC4,FBXW7,STK32B,SBF1,SCN2B,SMPD3,SLC6A11,SCMH1,RIMS1,IQSEC2,AJAP1,ZFR2,MMS19,CDK20,METTL3,PRMT8,CA14,PLPPR2,MKRN3,FAM182B" Coexpression 17108109-Table2a Human Lung_not_cancer_Carolan06_11genes GeneSigDB 1.11E-05 1.28E-01 3.05E-04 3.03E-03 8 10 "ASCL1,CHGA,ENO2,NCAM1,PENK,TAC1,UCHL1,SCG2" Coexpression M2878 Genes up-regulated in four lineages of epithelial cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.23E-05 1.42E-01 3.37E-04 3.35E-03 20 48 "CALB1,CDR1,CHGB,KIAA1549L,DOCK4,SNAP91,NTM,DYNC1I1,ETV1,ST3GAL6,GLDC,KIF5C,SCG3,NRCAM,PCDH8,RELN,SCG5,SNAP25,LMO3,HEY1" Coexpression M19632 Top 50 up-regulated genes in cluster MS of multiple myeloma samples with characteristic expression spike of WHSC1 [GeneID=7468]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.23E-05 1.42E-01 3.37E-04 3.35E-03 20 48 "KLHL13,MAGI1,CLGN,TCEAL2,MYRIP,ZNF521,CST3,DTNA,FGFR3,VWA5A,MARK1,MITF,NAP1L3,PBX1,PCSK5,SERPINE2,LRP12,PALLD,RUNDC3B,NSD2" Coexpression M9910 Genes down-regulated in dendritic cells: untreated versus 8h after infection of Leishmania major. MSigDB C7: Immunologic Signatures (v6.0) 1.27E-05 1.46E-01 3.46E-04 3.44E-03 54 197 "MTUS1,ABCD2,APBB1,SHTN1,ATP1A3,BMPR1B,DST,CACNA1G,IL33,HAP1,CAMK2G,SLC25A14,USP6,CLCN3,TPP1,CREB5,SNCAIP,ST18,RGS17,GPHN,ZNF391,RRAGB,BAIAP2,PCYOX1,NBEA,GABRA3,GPR162,PCLO,GRM7,MAPT,LRP1B,MEIS2,NEUROD1,PCDHGC3,PFKFB4,CEP41,MAPK9,GRAMD1C,LAMA1,RGS3,TMLHE,RPE,UEVLD,FAM192A,FHOD3,PKNOX2,SYT1,HIF3A,CDK20,RUSC1,AMOT,WNT7A,NAV3,SLC4A10" Coexpression M15780 Down-regulated genes in both rectal and colon carcinoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.32E-05 1.52E-01 3.59E-04 3.57E-03 33 101 "LRFN1,OSGIN2,CBS,LDB2,CACNA2D2,COL4A5,GREB1,CX3CR1,SIRPB1,FABP7,CHST15,FHL1,C2orf88,NR3C1,TOX2,ITPKB,NAT8L,SCAMP5,MITF,MSRA,MYCN,PRKACB,PTPRZ1,PRRT2,NUDT11,ST6GALNAC6,SNCA,UNC5B,CHST8,TGFBR3,TRPS1,SYNC,SLC30A3" Coexpression M13008 "Genes exclusively down-regulated in fibroblasts expressing the TTD mutant form of ERCC3 [GeneID=2071], after UVC irradiation." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.32E-05 1.53E-01 3.60E-04 3.58E-03 29 84 "AMPH,CDC42BPA,DST,SYNJ2,NECTIN3,CREB5,ARHGEF10,PHF14,DOCK4,CTIF,ZEB2,DMD,VPS13B,AHDC1,MALT1,HAS2,MIA2,MITF,PIK3C2A,ATXN1,WDR37,TMCC1,SON,GSE1,FAM168A,DOCK9,FAM155A,INTS3,NAV3" Coexpression M16533 Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion and down-regulated in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-05 1.55E-01 3.64E-04 3.61E-03 11 18 "ASIC2,CDC14B,LRBA,CNTNAP2,DLG2,NOP56,IDH3B,CDK14,SLC2A5,CLASP2,TBL1X" Coexpression M7068 Genes whose expression in optimally debulked ovarian tumors is associated with survival prognosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-05 1.55E-01 3.64E-04 3.61E-03 64 246 "RALGAPA1,TKTL1,NDRG3,APBB2,MARK4,NCOA1,CCDC181,MTMR9,WASF1,NFS1,CLDN10,FOXN3,ZFYVE9,CLTA,CP,CHD1L,CRY2,ARHGAP24,SPATA2,SACS,OPTN,AASS,EFS,TUBB4A,CAMSAP1,FLT1,ATP6V1H,NSG1,FYN,GAA,IQGAP2,TMEM8B,GFRA1,BTN2A1,GSN,IFI16,OPA1,PCSK5,PDE3B,PLXNB1,MSANTD2,RGS3,EXD2,STK32B,ITSN1,NTNG1,SLC14A1,ATF7IP,SLCO1A2,DOP1A,SON,SOX11,DOK5,ZHX3,SP4,EMC1,CDK19,GSE1,JMJD6,SYT1,DNMBP,PSD3,NSD1,LEFTY2" Coexpression 19549311-SuppTable2-MMLandPhenotype Human Leukemia_Zangrando09_1001genes GeneSigDB 1.39E-05 1.60E-01 3.74E-04 3.72E-03 137 628 "ACTN1,FMNL2,GRAMD1B,ESYT2,AK2,ALCAM,GAS7,ARHGAP5,MARCH3,ASPH,ZSCAN18,BCL7A,BID,WASF1,CAMK2D,CAST,CD38,RCBTB2,MS4A7,RPL32P3,TPP1,LY86,HOMER3,PNKD,CSF1R,CSF3R,ARHGEF10,CSNK1E,VCAN,CST3,PPP1R16B,GPSM1,RIPOR2,LONRF1,SIRPA,YTHDC1,ZEB2,SV2A,NR1D2,RCAN1,EBF1,HIPK3,FRY,PLXNC1,AASS,LPAR6,PAN3,DCTN4,RCSD1,RPS6KC1,TBC1D16,PRAM1,SCML2,FCGR1A,FGR,FHL1,TPK1,FYB1,GAB1,CAB39,ARPP21,ZNF274,SEPT9,ADAM28,GNAS,GPD2,GPM6B,NR3C1,NCKAP1L,IDH3A,IFI16,IL6R,DIPK1A,ITGAM,JAK2,KIT,LAMP2,LIG4,SMAD1,PIK3AP1,LYPLAL1,MAT2A,MBNL1,MEF2C,MEIS1,CD200,NINJ2,NPY,NRGN,P2RX7,ZNF827,CYTL1,CDK14,SSH1,SNX10,PLTP,RC3H2,CRLS1,PPP3CC,PRKCZ,PTCH1,REV3L,RFX2,RPRD1A,ACER3,ATXN1,PRCD,SELL,GALNT10,COPZ1,SLA,ARHGEF40,SLC22A4,SMARCA4,PALLD,ZNF423,SAMSN1,ZC4H2,NXT2,SYT1,DMXL2,KIAA0930,ZEB1,PSD3,SIK3,TMPO,TPM2,TPM4,SSBP2,TTC3,TMEFF2,SGK3,SLAIN1,KCNK12,ZXDA,SIGLEC10,MSRB3" Coexpression M8617 Potential direct target genes for MIR34A [GeneID=407040] microRNA in IMR32 cells (neuroblastoma). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.41E-05 1.63E-01 3.81E-04 3.78E-03 43 146 "TMCC3,HACE1,AK2,PKP4,MTMR9,RAB29,CALB1,NUMBL,TMEM184B,CREB5,PPP1R16B,PNPLA8,CTNND2,EARS2,RCAN1,E2F5,ST8SIA3,TMEM35A,EPB41,MRPL10,ACSL4,ARHGAP36,KCNK3,KIT,MDM4,MID1,MPP2,PDGFRA,JAKMIP1,PKIA,PROX1,ZYG11B,FIGN,LGR4,PALLD,ZCCHC24,SYT1,SYT4,OBSL1,SLC44A1,TPD52,MGAT5B,SLC38A1" Coexpression M1955 Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent trimethylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.43E-05 1.65E-01 3.84E-04 3.81E-03 16 34 "NCKAP5,ANK3,INSYN2B,CALY,ZEB2,KCNMB2,SYT3,MCHR1,HTR2A,IGF1,KCNA4,TMEM255A,SUSD4,YPEL4,C11orf87,SYT1" Coexpression M9243 Genes down-regulated in dendritic cells: untreated versus hydrogen peroxide [PubChem=784]. MSigDB C7: Immunologic Signatures (v6.0) 1.43E-05 1.66E-01 3.84E-04 3.81E-03 53 193 "ABHD6,ADD3,CEP126,ANK3,APAF1,EPB41L5,BCAS1,ZSCAN18,ZBTB10,ATP2B1,DOCK11,CDK5R1,HIP1R,FMNL3,ARHGEF2,BTF3L4,CDC42BPB,PHF14,HDAC9,TBC1D5,SCRN1,SPOCK2,GIT2,ELMSAN1,DMD,DOCK2,SIDT2,EBI3,IQCG,NEK6,AHDC1,PSIP1,MAP4K5,SYNPO,ZNF678,KIF5C,KPNA5,MYO9A,NTRK3,POU6F1,PPP2R5E,PROX1,PTK2,TMEM260,PYGM,KHDRBS2,ST3GAL3,MYCBP2,FBXW11,WASHC4,CYB561A3,ZNF610,LAT2" Coexpression M2737 Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of EZH2 [Gene ID=2146] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.43E-05 1.66E-01 3.84E-04 3.81E-03 53 193 "ASIC2,PPFIA4,IL33,PTBP2,CCK,ADGRG1,COL4A5,AATK,KIAA0513,CNIH3,DMD,EDN1,ANKRD46,RGS17,TMEM35A,ETV1,RASL12,CORO2B,B4GALNT1,GPM6B,GPR37,IRF8,SHISAL1,IL6R,DIPK1A,KCNA1,KCNA2,KCNJ10,L1CAM,VWA5A,FXYD6,NOVA1,PCBP3,PCDH9,PKIA,MTMR10,PTHLH,PTPRB,SLC6A15,TTLL7,TMEM100,CLIP1,ATXN1,ST6GAL1,WDR37,ABLIM3,SLC14A1,PLCB1,POPDC3,TUB,DNAJC12,VSNL1,PMEPA1" Coexpression M7005 Genes up-regulated in hematopoietic stem cells versus megakaryo-erythrocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-05 1.67E-01 3.86E-04 3.83E-03 46 160 "ACTN1,ADCY6,CARNS1,USP28,FOXK1,SLC25A27,ABCG1,LRIG1,IPCEF1,RASGRP1,PLEKHA1,CHST15,EVL,RAPGEF6,SESN1,TDRKH,RAPGEF4,BACH2,IL6ST,SLC11A2,EXOSC10,SIDT1,EML5,BEND5,RGS10,RIC8B,WLS,AP1AR,SELL,ST6GAL1,ST8SIA1,DZIP1,RUFY2,SLC14A1,SCMH1,TET1,EPC1,TNIK,MGRN1,TCF7,ZEB1,TGFBR3,SSBP2,TTC3,TOM1L2,PARP6" Coexpression 19523942-Table1 Human Brain_Potter09_66genes GeneSigDB 1.47E-05 1.70E-01 3.91E-04 3.88E-03 23 60 "ASCL1,CRMP1,CX3CR1,RASSF2,SPOCK2,FABP7,OLFM1,CHL1,GAD1,GFAP,GPM6A,GRIA2,NBL1,NKX2-2,PFKP,SNX10,PLP1,PMP2,PTPRZ1,RNASE1,S100B,SNAP25,SYT11" Coexpression M10156 Genes up-regulated in SaOS-2 cells (osteosarcoma) upon expression of PAX3-FOXO1 [GeneID=5077;2308] fusion protein off an adenoviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.47E-05 1.70E-01 3.91E-04 3.88E-03 23 60 "LGR5,TMEFF1,SLIT2,CNR1,DMD,SH3GLB1,PLXNC1,CALCRL,TPK1,PCDH17,GNAS,GPM6A,LIFR,KITLG,PBX1,LRRN3,PTPRG,SGK1,PEG10,CLSTN2,KAT6B,TUBB1,PLSCR4" Coexpression M5580 Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.48E-05 1.71E-01 3.93E-04 3.90E-03 54 198 "ACTN2,BIN1,CNTNAP1,APLP1,SCAPER,DCLK1,CCPG1,RCBTB2,STOML1,NRG2,ENTPD4,DOCK4,ZNF337,CNIH3,SGSM2,NR1D2,E2F5,RASGRP1,EEF1D,EZH1,F8,MALT1,MSL3,PRRC2B,LILRA1,GPR17,CROCCP2,ADAMTS8,BTN2A1,HNF4G,HSPA1L,IL11RA,KIF5C,L1CAM,MBD1,MGAT3,MYO6,ACSS3,ZNF532,SCN2B,R3HDM2,INAVA,SON,CEP68,DDHD2,PHF24,AHCYL2,SEZ6L,UBE3A,ZIC1,ZSCAN26,SLC30A3,GDPD5,NAV3" Coexpression 19351829-SuppTableA Human Lung_Daniel09_314genes GeneSigDB 1.56E-05 1.80E-01 4.12E-04 4.09E-03 73 292 "RALGAPA1,AS3MT,EMILIN3,PLEKHH1,PKP4,API5,ATP2B3,N4BP2L1,CFLAR,MTMR3,MTMR2,CARS,CLCN3,NRXN1,COL9A3,MAGED1,ABI3BP,RCHY1,CTH,ARHGEF4,ARMCX4,KIF19,HS3ST4,ATN1,HIPK3,MBNL2,SRPK3,PAN3,FDFT1,FGF12,FGFR3,MSANTD4,NTNG2,GPT2,GPD2,KLF12,ELOVL5,HMGCR,STXBP5,MAP4,MYO7A,NACA,HNRNPM,NF1,NOS1,TRHDE,PSAT1,SDK2,DRAM2,MAPK8,DEF8,CNTLN,RAP1GDS1,ROBO1,AP1AR,SARS,BTBD3,SMTN,ABTB1,PDZD2,RHBDL3,CAMSAP2,CDH22,RELL2,CABIN1,PRMT8,PITPNB,VAV2,KCNK12,PMEPA1,SHD,NAV2,NETO2" Coexpression M828 Genes down-regulated in breast cancer tumors (formed by MCF-7 xenografts) resistant to tamoxifen [PubChem=5376]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.56E-05 1.81E-01 4.12E-04 4.10E-03 66 257 "ABAT,ADD3,APBB2,ZBTB10,WASF1,CA12,CALB2,SCARB1,LONRF2,LARGE1,COL4A5,LRIG1,ATRNL1,GREB1,RHOBTB1,DSCAM,EFNB3,EGR3,DLC1,OLFM1,TMEM164,FOXO3,GFRA1,GPER1,ARHGAP36,ELOVL5,HNMT,IGSF1,TUBB2B,ZNF385B,KCNJ3,LAMP2,SYTL4,MAP2,MAPT,NRCAM,GPR173,PIK3R1,MBOAT7,APTX,ELOVL2,PTPRG,SUSD4,RBBP8,ELP2,RXRA,IL17RB,SH3BGR,SYBU,NBPF1,MYO16,KDM4B,SOX3,TSPYL2,SYT1,ATP11A,KAZN,PCDHGA4,TIAM1,CBX5,TNNT1,NEIL2,TST,SGK3,CADM1,MAP3K12" Coexpression 20436685-ST4-2 Human Breast_Pothuri10_526genes GeneSigDB 1.60E-05 1.85E-01 4.21E-04 4.18E-03 112 495 "ADAR,ADARB2,ADCY2,KLRC4,ADD1,MTUS1,ANK1,ANK2,APBB1,GAS7,NUMB,B3GALT2,RGS11,CFLAR,CALB1,KALRN,CAMK2B,CH25H,RUNX1T1,CD81,SEPT7,CDC42,LRRFIP1,CDO1,LHX2,NRXN3,ABCG2,CNN3,PICK1,TCEAL2,CLOCK,CREB5,CHD5,CNTNAP2,DAPK1,SIRPA,MED24,CHRDL1,EXOG,TRAPPC9,EIF1,ETV1,EFEMP1,FGFR1,SORBS1,FYN,DKK3,GABRB1,MYOZ2,GATM,GLUL,DCLK2,GNAS,LILRB4,PTGDR2,HLF,IFI16,IL6ST,DIPK1A,KCND3,KHK,KTN1,MAOB,MAPT,MBNL1,MEIS2,BCO1,MT1M,SCG3,MTTP,NAP1L3,NF1,NUCB1,OPCML,PCSK2,PDE3A,PSAT1,LRRN3,PPP3CC,MAPK7,GDPD2,TMEM104,PYGM,RASGRF1,RET,RORB,GALNT10,CHD9,SEC31A,INTS9,SNCA,NPAS3,ATP10B,CLSTN2,STX1A,ARC,MGRN1,DOCK9,OBSL1,NSD1,TMOD1,TNS1,TPM1,SYNPO2,TRIO,TSC2,UBC,CLDND1,TRIM9,REEP1,ZFAND5,SEMA3B" Coexpression 20003503-SuppTable1 Mouse Lung_Moulos09_925genes GeneSigDB 1.61E-05 1.86E-01 4.22E-04 4.19E-03 144 668 "ADCY6,PWWP2A,ESYT2,HECW2,TBC1D14,AMPD3,OGT,PHF12,FAM131A,APP,ASPH,NCOA1,KIF1A,BARD1,GPR146,DST,CAMK2D,CAMK2G,CARS,P2RX6,SCARB1,SLIT2,CLU,HS3ST5,PNKD,ENTPD4,ABCG1,MICAL2,OSBPL3,PLCH2,PHF14,DOCK4,LONRF1,DAPK3,DBI,PITPNC1,ZBTB24,EXOG,RAB39B,DRP2,AASDH,KLHL5,SIDT2,RBM12,YAF2,SUGP2,EIF4G2,EIF5,ING4,PCOLCE2,GPHN,SRRM1,GMPR2,NRN1,FAM198B,ACSL4,EFEMP1,TESK2,POLR1B,VTI1B,ZCCHC17,TMEM107,USP16,PDLIM5,CELF1,SARAF,TPPP3,DKK3,DENND2A,PCSK1N,PSIP1,HAS2,NCKAP1L,DDX19B,ATXN2L,GATD1,SFXN5,HECTD2,MAT2A,LDLRAD3,N6AMT1,NAP1L1,NASP,NDUFA5,DDR2,PAX6,PDE4A,ENPP2,SMOX,LRP12,POU6F1,PPM1B,PPP3CB,PPP5C,CEP41,MAPK8,NDUFS7,RAB3IL1,CEP97,ATG16L1,RBBP6,KHDRBS2,RDX,SLC6A15,GTDC1,LGI2,WLS,RMI1,SALL1,TRA2B,COPZ1,HSPA4L,LIMS2,WDR47,SEPHS1,NAPB,SMARCA4,OGDHL,SMARCD3,SON,SPATA7,GLT8D1,KDM4C,SEPT8,FAM168A,PRRC2C,POPDC3,SMG6,ATMIN,CLASP1,WDR7,AZIN2,TNNT1,TPM3,WBP2,TSN,TFIP11,ZFAND5,UPF3A,MPPE1,FAM13C,UBE3B,RNF170,SOCS4" Coexpression M2951 Genes up-regulated in induced T reg: wildtype versus non-functional FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.61E-05 1.87E-01 4.22E-04 4.19E-03 48 170 "ARID1A,ADCY6,CARNS1,USP28,SFMBT2,DOCK11,ENTPD2,KBTBD11,CELSR3,PLEKHA1,LRRC23,SLC43A2,CD320,CHST15,EVL,RAPGEF6,SESN1,GGT5,TDRKH,RAPGEF4,TMEM25,HSD17B1,IL6ST,SESN3,SLC11A2,TMIE,NLE1,SIDT1,PTK2,EML5,PEX5,CEP97,RGS10,CLIP1,SATB1,SELL,GALNT10,MAGI3,DZIP1,TET1,ARFGAP1,STX1A,TCF7,TGFBR3,SSBP2,TTC3,PMEPA1,CPNE4" Coexpression M8239 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells treated by digoxin [PubChem=2724385]: wildtype versus RORC [GeneID=6097] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.61E-05 1.87E-01 4.22E-04 4.19E-03 48 170 "RALGAPA1,ARID1A,TAOK1,USP37,ATM,ATP2A2,DOCK11,BARD1,CDC25B,KMT2C,MAP4K4,NCOR1,SIPA1L1,PITPNC1,SRGAP3,CNNM1,CORO2B,ATP8A1,MED12L,SLC37A3,SMC2,IQGAP2,KAT7,TOX2,NF1,PIK3CD,PKM,VPS13C,IL17RB,PPM1E,FNDC3A,ST8SIA1,ATF7IP,KIF21B,ZHX3,UHRF1BP1L,ERC1,TBCEL,ZEB1,RPGRIP1L,FRYL,ZNF106,TSC2,NSD2,WRN,WNK1,PRDM10,DOCK8" Coexpression M10016 Genes up-regulated naïve CD4 [GeneID=920] T cells: Ly6c+ versus Ly6c-. MSigDB C7: Immunologic Signatures (v6.0) 1.62E-05 1.88E-01 4.24E-04 4.21E-03 52 189 "C3orf14,PTCHD1,GPR158,PCDH19,ALCAM,TMEM108,ATP2B1,ZNF583,GPRASP1,KIF26A,OLIG1,ARRDC4,EDIL3,RGS17,ENO2,RCAN2,EPHB1,RAB9B,EZH1,CHST15,ACSS1,MSL3,HLF,CPT1C,LINC00667,BCO1,NELL1,DPY19L2P2,GPR85,SERPINI1,NALCN,ZNF655,PRRX1,HYDIN,SYTL2,QDPR,TMEM200C,IL17RB,NLGN4Y,PALLD,ERC1,BEX1,ZNF621,TAC1,TMEM178B,ANO5,ZNF610,CCDC14,CLDND1,TCEAL7,LAMP5,JPH3" Coexpression 16491124-SuppTable1 Human Breast_Doane06_145genes GeneSigDB 1.66E-05 1.92E-01 4.31E-04 4.28E-03 33 102 "ABAT,KIAA1324,ALCAM,AZGP1,BMPR1B,CA12,CACNA1D,CLGN,SLC4A8,GREB1,EEF1A2,ERBB4,EVL,SYT17,GFRA1,RND1,TOX3,MAPT,MYO6,PBX1,SIDT1,ELOVL2,RET,STK32B,SYBU,IFT122,CLSTN2,SYT1,TNNT1,DNAJC12,MAP3K12,DNALI1,SEMA3B" Coexpression M1967 "Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV8.1 (induced pluripotent cells, iPS)." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.66E-05 1.92E-01 4.31E-04 4.28E-03 33 102 "ASIC2,ACHE,CACNA1G,CACNA1E,CALB1,CRLF1,TMEM59L,NTM,NRN1,CACNG2,ZMYND10,FGF12,ACTL6B,PCDH11X,GRM8,HPSE2,NFIX,LRRK2,KCNIP1,ARX,SLITRK3,RPH3A,SORCS3,MYCBP2,ADGRL3,PCDHB7,PCDHA2,NR2E1,PRRT1,FAM155A,VSNL1,CA10,PRDM8" Coexpression M16009 Genes whose DNA is hyper-methylated in hepatocellular carcinoma (HCC) compared to normal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.67E-05 1.93E-01 4.33E-04 4.30E-03 192 935 "ASIC1,CSMD3,ADARB2,ADCYAP1R1,ADD1,UNC5A,KIAA1211,KIDINS220,SLC24A4,TXNDC16,C1QTNF1,ADGRF5,ANK1,ANK2,C6orf89,KCNAB2,LRRC4C,ARSF,KIF1A,BMPR1B,BTRC,CACNA1B,CACNB2,KALRN,RUNX1T1,CD86,ZMYM4,DLGAP2,ARHGAP22,KMT2C,TMEM184B,CNGA3,FHL5,CNR1,COL9A1,RGS6,CSF2RA,ARHGEF10,PLCH2,PDE4DIP,CST3,PLXNA4,RASGEF1C,ST18,FAM131B,GAPVD1,RIPOR2,ARHGAP24,PHYHIP,DGKB,DGKG,TMEM170A,DBI,ZNF804A,TIAM2,SV2B,AK5,TMCC2,DLX1,DMD,CALN1,DPP6,E2F6,TSPAN5,IRAK4,TENM1,KCNMB2,ADGRV1,FCGR1A,FCGR1B,FGF1,FOXO3,ST6GALNAC3,MSANTD4,FYB1,FYN,DISC1,CPLX2,FAXC,SULT1C4,MALT1,LYVE1,NTNG2,GLI2,GPR12,GRID1,GRIK2,ADAMTS13,GRM8,GUCY1A1,NCKAP1L,MIER3,SCRG1,IGFBPL1,KIAA1755,SCIN,KCNA2,KCNK2,KIF5C,STXBP5,TTYH2,SMAD9,MATN2,ADAM11,MEST,MOBP,ERICH3,CCDC80,MSRA,ZNF92,HS6ST3,MYH7,MYO5A,MYO9A,NEFM,PDE1A,A2ML1,JAKMIP1,PDZRN4,PPP2R2C,PKIA,GRAMD1C,DIRAS2,DCHS2,VPS13C,SYTL2,TMEM104,PTPRE,PTPRN2,ACSS3,CRTAC1,ARMC5,GSTCD,KIRREL1,EPHA10,FBXW7,STK32B,PTGR2,ABCA11P,SEMA6D,SCP2,ITSN1,FRMPD1,HKDC1,MAGI3,AMBRA1,FHOD3,NBPF1,SLC6A8,SLC8A1,RADIL,TMEM132D,SLC20A2,ATF7IP,TET1,GKAP1,SORCS3,DMRTC1,LIMCH1,PDZRN3,DOP1A,MYT1L,NFASC,CLASP2,CLSTN2,POGZ,AJAP1,ABCC8,FNDC9,ASTN2,TAC1,KAZN,CAMTA1,NEU4,PCDHGA2,PSD3,AKNA,HIF3A,ZFPM2,RASD2,TRPC3,TST,CCDC136,VIPR2,MKRN3,SPIRE1,MDH1B,NAV2,TMEM163,WNK2,KAT6A,NLRP3" Coexpression M6735 Genes up-regulated in B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.68E-05 1.94E-01 4.34E-04 4.31E-03 53 194 "ADCY6,OSBPL1A,TBC1D14,KCNAB2,GPR146,SYNJ2,LDLRAD4,CA8,CABP7,ZBED1,CLCN4,CREB5,MICAL2,PLCH2,KIF26A,CHRDL1,DMTN,MAD2L2,PRKAG2,GAD1,WASF3,POLL,ADAP1,STON1,GPR45,HMGCL,INPP1,TUBB2B,KIF5C,KIT,MBP,MN1,SSH1,EXOSC10,PPP2R5C,PKIA,PTCH1,RGS10,NUDT11,FAM102A,YPEL4,INTS9,EPB41L3,NKAIN2,LRRC4,RGL1,TACC1,SEMA4A,NACC2,DDHD1,TNS1,TUBB2A,CLDND1" Coexpression 19286929-SuppTable2h Mouse Lung_Rangasamy09_98genes GeneSigDB 1.71E-05 1.98E-01 4.38E-04 4.35E-03 29 85 "AQP4,AQP6,ATP1A2,ATP1A3,CACNB2,SLC25A27,SMARCAL1,SLC35F1,ABCG1,ZFYVE16,TBC1D5,SLC12A6,CACNG7,SLC37A3,ATP2C1,GRIA2,GRIA4,GRIK2,KCND2,KCND3,KCNJ3,KCNJ5,SLC6A15,SCN3A,SCN7A,SLC1A3,SCN3B,KCTD2,KCNT2" Coexpression M3136 Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "KDM5D,NDRG3,ADORA3,AP2A2,HACE1,ATP6V0A1,DOCK11,DCAF5,LARGE1,CFL2,CNRIP1,CREB5,BLOC1S6,NR1D2,ABCC5,PAN3,EPS8,PIPOX,RTN3,KAT8,CAB39,MITF,PDE2A,PFKFB4,C11orf49,PTPA,PPP2R5C,SNRK,ZNF615,ROGDI,RFX3,PCMTD2,SELL,ASRGL1,ITSN1,ST6GAL1,CCDC88A,SLC15A2,DOP1A,KDM3A,MYCBP2,SPTAN1,SRPK2,CEP68,ATP11A,SYNE1,SLC44A1,ZFP91,XPO1,ZNF19,GOPC,NUP214,JMJD1C,RNF170" Coexpression M5682 Genes down-regulated in comparsion of ActTreg versus ActTregTGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "MTA3,MTUS1,GPR158,CDC14B,ATP1A2,STX16,MTMR3,LDLRAD4,MAP7,FMNL3,CD38,AKAP5,MYRIP,IPCEF1,GREB1,ARHGEF4,CTIF,GIT2,EXOG,C8orf37,TBC1D16,PRKAG2,FUT9,INSM2,LPAR4,GPER1,STMN2,GUCY1B1,LDLRAD3,MYO9A,IGSF11,P2RY1,PDE2A,GNG2,POU6F1,PRKCG,WBP1L,PTPRO,ROBO1,ATXN1,ST8SIA1,SLC11A1,MAPKBP1,DBNDD2,SPTAN1,TSPYL2,EPB41L3,ZSCAN29,ANKRD12,ACSL6,USP22,TTC3,AMOT,NDRG4" Coexpression M3241 Genes up-regulated in comparison of naive B cells versus Ig isotype switched memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "ADORA1,PPP4R4,BCHE,RGS11,MTMR2,CACNG1,CAMK2B,CBS,RGN,MTMR7,DGKI,SULT4A1,PCYT1B,NECTIN3,AKAP12,FAM169A,HEPH,MFAP3L,DLG3,DMPK,EDNRA,HIPK3,EYA1,OLFM1,HPCAL4,PPARGC1A,HSD17B1,MATK,GIT1,NBL1,NPTX1,PDZRN4,MAGEL2,CNTLN,RASGRF1,RTN1,SCG5,SLN,INTS9,RIMS1,PALLD,NPAS3,LMO3,ARC,SYP,FAM189A1,PCDHA2,HIF3A,GPR161,SEZ6L,HSPBP1,AMOT,NDRG4,DPF3" Coexpression M8693 Genes up-regulated in monocytes (6h): M. tuberculosis 19 kDa lipopeptide versus M. tuberculosis 19 kDa lipopeptide and muramyl dipeptide [PubChem=11620162]. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "CPNE2,GALNT16,ADCY6,USP31,KIDINS220,SNX32,DGKD,LGR5,CDC14B,DACT3,ATP1B3,ADAM23,SNAI3-AS1,HCN2,PRC1,CNN3,ENTPD4,KIAA0513,SCRN1,IP6K1,DCC,KIAA0319,DDX46,SEMA3D,EGR3,TMEM132E,RASA4,ING4,DMTN,GABRA2,IQGAP2,INPP5K,SPACA9,GRM2,LINGO1,NF1,GPR88,PAH,PALM,EPN1,PIGG,TMEM231,RFX5,NUDT11,ZFHX4,ZNF354C,TRIM46,ZBTB43,TCF7,DDHD1,PIK3R5,NPDC1,KCNK12,ZBTB16" Coexpression M6651 Genes up-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL6 [GeneID=3469] and LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "ADCY6,LRCH2,PPFIA2,ARHGDIG,ZBTB10,HCN2,DNAJB5,C4orf33,SLITRK5,DCTN1,CD99L2,EDNRB,FEM1B,SUGP2,ARMCX1,ATP6V1H,KHDRBS3,CGREF1,GPR153,NSG1,TBR1,CYP46A1,GNAO1,CECR2,GRIA2,UBE2QL1,CPT1C,IGFBP1,LRRCC1,MYO6,NAP1L2,NBL1,VWA2,PDYN,PNMA3,PPP2R5E,LAMA1,MDGA2,STK32A,LGI2,RPL38,MAP6D1,KIF21A,TMEM132D,SOX5,ZHX3,RAP1GAP2,SEPT3,AZIN2,GPRIN3,ICAM5,WNK1,FAM47E,FAM181A" Coexpression M7605 Genes down-regulated in CD11b+ cells from BALB/c mice bearing C26GM colon carcinoma: spleen versus tumor. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "ABAT,CLK4,ADD3,ARNTL,BACH1,BCL2L2,SRSF11,FOXN3,SH2B1,NCOR1,FEZ2,ZNF337,MAML1,IST1,PLEKHM1,FBXL5,ZC3H11A,NR1D2,ABI1,ABCC5,KMT5B,USPL1,PLEKHO1,PIPOX,KIAA1109,EVL,STAG2,BTN2A1,KLF12,GABARAPL2,KLRC3,VWA5A,LSS,ZNF862,PIK3CD,PRKCZ,WBP1L,SNRK,PTCH1,TMEM260,TUG1,CASC3,TTC17,SON,MYCBP2,SPTAN1,ERBIN,FCHO1,VAMP1,CLASP1,FRYL,WIPF2,MPPE1,HNRNPA3" Coexpression M10018 Genes up-regulated in macrophages: control versus tumor associated. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "NDRG2,FMNL2,PTCHD1,AMPH,GPAM,PROM1,SEPT7,CHN1,ABCG2,CNTN1,CNRIP1,DCAF4,LYPD1,SACS,EDIL3,EDNRB,KLHL5,OPTN,RBM12,PSMA3-AS1,FGF13,UBE2E3,ZNF559,DNER,GHR,DBF4,GPD2,NR3C1,UBE2QL1,MSL1,SCIN,IL6R,KCNN2,SAMD5,HS6ST3,NFE2L2,GPR85,GNG2,PRRX1,MAPK9,NDUFS7,PLEKHB2,TTLL7,RTN1,TMEM200C,ZNF365,SEPHS1,BTBD7,FAM126B,RBM26,ZNF621,TAC1,DDHD1,TCEAL7" Coexpression M8143 Genes down-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "NME5,APOC1,ATP2A2,ADGRB2,ARHGEF7,THSD7A,INA,CDH2,CDO1,FAM189A2,FHL5,COL4A5,COX4I1,CSF1,ZNF337,SPATA2,DNAJC6,JAKMIP2,ECM2,SIDT2,PLEKHO1,VPS13B,PIPOX,FDFT1,DENND2A,GAD1,GFAP,GLS,BTN2A1,SLC2A6,KLRC3,LSS,NCAM2,OGG1,OPA1,RFX5,RGS12,RLBP1,SEMA6D,SCNN1D,PREX2,KDM4B,PRRC2C,FAM208A,WWC1,FBXW11,TEK,TGFBR3,SPHK2,TFIP11,ADAMTS9,PHTF2,GJC2,JPH3" Coexpression M6371 Genes up-regulated in bone marrow-derived mast cells: wildtype versus ADCYAP1R1 [GeneID=117] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.73E-05 2.00E-01 4.38E-04 4.35E-03 54 199 "NDRG2,OSBPL6,SLC7A14,SLC4A4,ATP2B3,KIF1A,FOXK1,VXN,CBLN1,CD86,NUMBL,FOXN3,CNN3,C2CD2,CRMP1,MICAL2,SEC14L5,AIF1L,ELN,DENND4A,FGF12,FGR,SEMA6C,CPLX2,GCNT2,GPR162,MAP7D2,CCDC184,LRRC75A,GAREM2,BRINP3,KCNF1,KCNJ9,KIF5C,MGAT3,MMP17,PDZRN4,PACSIN1,FA2H,IRX1,PRR5L,SEMA6D,SCN2A,ANKRD6,ZNF334,ST5,CEP68,RGL1,STX1A,SYN2,VWA3A,TRIM9,PMEPA1,KCNAB1" Coexpression M7635 Genes up-regulated in memory CD8 T cells: 3' versus 4'. MSigDB C7: Immunologic Signatures (v6.0) 1.77E-05 2.04E-01 4.46E-04 4.43E-03 50 180 "RNF150,APOC2,ARHGAP5,USP2,SCARB1,CDO1,SOCS6,ACBD5,DBI,DMPK,CPEB2,DPYSL2,RCAN1,LPAR6,PLEKHO1,EPS8,PRAM1,FCGRT,HPGDS,PRUNE2,GSN,ICA1,KHK,KIFC3,LMO2,VWA5A,LDLRAD3,P2RY13,NME4,PDE4D,SLC22A23,UHRF1BP1,RAB3IL1,ZDHHC14,GAL3ST4,RGS10,RASA3,CHD9,ST6GAL1,SLC15A2,SLC37A2,CAMSAP2,WDR7,AHCYL2,TMEM9,SGK3,LAT2,NAV2,PLD4,JMJD1C" Coexpression M13671 Up-regulated genes distinguishing between M1 (pro-inflammatory) and M2 (anti-inflammatory) macrophage subtypes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.80E-05 2.09E-01 4.54E-04 4.51E-03 28 81 "ALAD,FAM135A,FGD2,LCORL,DST,RCBTB2,CNRIP1,GDA,BLOC1S6,ENO2,ACSS1,GATM,TUBB2B,KCNJ10,PIK3AP1,NAT8L,LYPLAL1,MSR1,P2RY13,NRCAM,PPP2R5C,RFX3,EMC1,FAM124A,TTC3,CADM1,ATP6V0E2,PIANP" Coexpression M6770 Genes up-regulated in splenic dendritic cells: DEC205+ versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.82E-05 2.11E-01 4.57E-04 4.54E-03 44 152 "HECW2,AQP6,SLC7A14,CCDC74A,CACNA1G,CACNB2,DLGAP1,CHRNA4,RAB33A,GPSM1,AIF1L,NTM,EFNA2,TMEM74,OLFM1,FGFR3,GABRA3,ACSS1,STARD10,AIFM3,GRIN1,GUCY1A2,HRH3,KCNJ11,KCNK1,KIFC3,MDFI,PPM1L,BCO1,NRBP2,HS6ST3,BEST3,GDAP1L1,PPP3CC,STRC,TMEM200C,SLC4A3,EPN2,ABTB1,HIF3A,TNR,DCBLD1,ATP6V0E2,REEP1" Coexpression M6860 Genes up-regulated during B lymphocyte differentiation: pre-B I versus small pre-B II. MSigDB C7: Immunologic Signatures (v6.0) 1.82E-05 2.11E-01 4.57E-04 4.54E-03 44 152 "FMNL2,FAM135A,SFMBT2,ARHGAP5,CD81,MAGED1,FEZ2,RHOBTB1,RABGAP1L,KCTD3,SYNCRIP,ANKFY1,TMEM175,STAU2,ALDH1L1,GRIN2D,ZDHHC15,HECTD2,SCAMP5,RCOR2,PDE3B,SSH1,PLCL1,PRKCB,RAB39A,BEND5,ST6GAL1,SLA,SLC12A2,NAPB,SLN,GKAP1,SCN3B,ZHX3,CAND2,MESP1,ATP11A,ANO4,TCF7L2,ARHGEF12,TMEM9,KLC2,SLC30A4,SLC17A6" Coexpression 18425577-TableS3b Human Breast_Creighton09_90genes GeneSigDB 1.88E-05 2.18E-01 4.71E-04 4.68E-03 27 77 "SERPINA3,NME5,C1QTNF3,SPARCL1,APBB2,ZSCAN18,ADGRB2,CACNA1D,CAST,CRY2,CX3CR1,LRRC17,IL6ST,KCND3,LAMA2,MAPT,NOVA1,SPATA6,QDPR,ZC3H14,SYBU,ZNF415,TGFBR3,ZNF177,ZSCAN26,DNALI1,NAV3" Coexpression 18593951-TableS2 Human Ovarian_Bonome08_263genes GeneSigDB 1.95E-05 2.26E-01 4.82E-04 4.79E-03 60 229 "TKTL1,NDRG3,APBB2,MARK4,NCOA1,MTMR9,WASF1,NFS1,CLDN10,FOXN3,ZFYVE9,CLTA,CP,CHD1L,CRY2,ARHGAP24,SPATA2,SACS,OPTN,AASS,EFS,TUBB4A,CAMSAP1,FLT1,ATP6V1H,FYN,GAA,IQGAP2,TMEM8B,GFRA1,BTN2A1,GSN,IFI16,OPA1,PCSK5,PDE3B,PLXNB1,RGS3,EXD2,STK32B,ITSN1,NTNG1,SLC14A1,ATF7IP,SLCO1A2,DOP1A,SON,SOX11,DOK5,ZHX3,SP4,EMC1,CDK19,GSE1,JMJD6,SYT1,DNMBP,PSD3,NSD1,LEFTY2" Coexpression 19286929-SuppTable2n Mouse Lung_Rangasamy09_254genes GeneSigDB 2.00E-05 2.31E-01 4.82E-04 4.79E-03 62 239 "ADCY6,TAOK1,BCAR3,ARHGAP20,ANK3,PPFIA2,CASK,ARHGAP5,BTK,KALRN,LRBA,MAGI1,TAOK2,SIPA1L1,SOCS5,DOCK4,GIT2,MAGI2,RABGAP1L,SRPK3,CALCRL,DLC1,GPR34,GUCY1A1,GUCY1B1,IRAK3,ITPKB,ARHGAP12,GPR155,PDE2A,GPR85,PIK3CD,GPSM2,MAPKAP1,PILRA,SH3KBP1,PPM1B,PPP2R5E,PPP3CB,PRKCB,PRKCZ,PTPRD,PTPRO,KHDRBS2,RGS3,RGS4,RIT2,RTKN,ITSN1,KIF13A,TMCC1,KIF1B,NPAS3,FGD4,ADGRL3,ARHGAP9,TIAM1,RASD2,P2RY12,WNT7A,CAB39L,FZD3" Coexpression M4716 "Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.00E-05 2.31E-01 4.82E-04 4.79E-03 62 239 "ACHE,STX16,SYNJ2,CAMK2G,ARHGEF2,CDR1,CCPG1,CHM,CLU,CLTB,PCYT1B,AKAP6,CREM,CREB5,ABCG1,LRIG1,SUSD5,CTH,SPATA2,KIAA0319,DYNC1I1,DTNA,TOM1,DNAJB6,EIF5,BSCL2,EPB41,CAP2,FLNC,GLS,IL6R,ITGA7,LMO2,MAP2,MEST,KITLG,NUCB1,PCSK1,SMOX,MBOAT7,TNPO2,PRKCZ,MAPK10,SNRK,PSMD13,PTPRN,HSPA4L,ABLIM3,SLC12A4,PALLD,SPP1,KIF1B,TSPYL2,NSFL1C,JMJD6,TAC1,AGTPBP1,KIAA0930,THBS4,NACC2,UBE2H,PRDM2" Coexpression 19658189-TableS8c Human EmbryonicStemCell_Xu09_63genes GeneSigDB 2.02E-05 2.33E-01 4.82E-04 4.79E-03 23 61 "ACTN2,ANK1,ANK2,MYH7B,MYRIP,DYNC1I1,DMTN,CORO2B,FLNC,SORBS1,PDLIM5,FYB1,GSN,AFDN,CTNNA3,MYH6,MYH7,MYL3,SMTN,PALLD,SPTB,TPM1,TPM2" Coexpression M7782 Genes down-regulated in memory CD8 T cells: wildtype versus TCF7 [GeneID=6932] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ACTN1,CDC7,CCAR2,ATM,BCL7A,BLM,PRC1,CD81,AP4M1,LRWD1,EPS15L1,SLC4A7,RTTN,CSF1R,RIPOR2,DCAF8,RABGAP1L,FAM107B,DLX1,DNAJB6,MRNIP,GPHN,TUBA1B,SLC37A3,ZNF512,GPR34,ELOVL5,ZDHHC15,DOCK7,LRRCC1,KIT,MN1,LYRM9,PPP3CA,PTK2,FAM120C,ZDHHC14,RFX5,RTN1,DGLUCY,SEPHS1,MYCBP2,SPART,ANKRD28,DDHD2,PDLIM2,TCF7L2,WDR7,TMPO,RUNDC3B,AMACR,TTC3,MPPE1,SPATA13" Coexpression M6888 Genes up-regulated in CD4 [GeneID=920] T cells with in vivo expansion: IL6 [GeneID=3569] versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ABAT,ADD1,AP2A2,DGKZ,ARNTL,ARRB1,ASPH,BCL2L2,TRIM41,LDB2,LRBA,CDH2,CTNND2,IP6K1,DMD,PCOLCE2,RASGRP2,EZH1,FCGRT,TESK2,FHL1,FOXO3,SARAF,GBX2,GSN,COQ10A,LAMA2,STMN1,SCAMP5,CCDC80,NPR2,PKD1,PTPRB,UEVLD,RXRA,SCP2,GALNT10,MYO18A,PEX26,EFHD1,LIMCH1,SCN3B,EPB41L3,DNAJC9,CLASP1,SYNE1,ARHGAP9,ZMAT3,ZMYND8,CADM1,ZBTB14,PLD4,FAM13C,SSPN" Coexpression M9260 Genes down-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5+ BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "GPR146,LDLRAD4,CCNT1,ZMYM4,CFL2,KMT2C,MAP4K4,SLC25A27,COL11A2,ZFP28,ABCG1,PHF14,KBTBD11,DLG3,NR1D2,ATN1,EGR3,CHST15,SUCO,NSG2,ZMAT1,RAPGEF6,SPIN1,ATE1,HECTD2,SESN3,NFIX,NUCB2,PDE4B,MINDY2,PSD,TMEM206,RPL38,CLIP1,ZNF354C,ST8SIA1,ZFP1,ZNF667,TMCC1,ERBIN,SULF2,CAMSAP2,ALG1,TBCEL,TCF12,THRA,R3HDM1,TRIO,RUNDC3B,SSBP2,TTC3,MPPE1,CERS6,JMJD1C" Coexpression M8115 Genes up-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by IL10 [GeneID=3586] versus NFKB1 [GeneID=4790] knockout macrophages stimulated by IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "TBC1D14,PDZD4,MAP4K3,KCNAB2,TMEFF1,CDK13,ATP6V0A1,KIF1A,GPR146,REPS2,GAL3ST1,NCOR1,MYADM,FBXL5,CD99L2,SEMA3D,TNK2,EPB41L2,CDKL3,FAM198B,PDLIM5,GAD1,SRCAP,KCNMB4,TOX2,MIER3,USP54,IL6ST,KIFC3,SMAD9,MBD1,KCTD6,MYO5A,PIK3R1,GPSM2,EPN1,PLTP,PTK2,PTPRN2,RAB3IL1,WDR37,MYO16,CLASP2,GANAB,ACSBG1,TCF4,PIK3R5,UCHL1,PLEKHH2,KCNK12,AMZ1,VANGL2,KLHDC1,RNF146" Coexpression M4136 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "CLK4,SLC25A25,DSCAML1,APAF1,ASTN1,EIF4G3,SRSF11,LHX2,RAB33A,CSF3R,PUM1,CX3CR1,TM9SF4,MYEF2,RUSC2,G3BP2,DLX1,DTNB,RASGRP1,CALCRL,DMTN,CD320,CAMSAP1,GABRB1,TRAF3IP2,RFFL,GRIN1,NR3C1,HES5,ITPKB,JAK2,PAXBP1,P2RX7,GLIPR1L2,GPR85,GPSM2,EPDR1,MAPK8,LRRC49,PTK2,PXK,USP47,RFX3,PCMTD2,SLC11A1,KBTBD4,SLC22A4,TET1,FBXW11,SMG6,METTL3,VAV1,PMEPA1,SOCS4" Coexpression M8110 Genes down-regulated in unstimulated macrophages: IL10 [GeneID=3586] knockout versus NFKB1 [GeneID=4790] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "VWA5B2,ERMN,MADD,NCOA1,DPY19L3,KIF1A,BCL2L2,LARGE1,NGEF,MAGED1,ZNF385A,SH2B1,LONRF1,DCC,PITPNC1,ZNF804A,EBF1,DCTN4,ERBB4,MRVI1,UFM1,FAM49B,SARAF,GAD1,ZMYND11,KCNMB4,CACFD1,MFSD2A,ATG4C,TOX2,TUBB2B,L1CAM,LAMP2,SYTL4,IGSF11,PIK3R1,SMOX,LRP12,TMEM104,HOGA1,SGK1,WDR37,RADIL,BTBD7,CPEB4,GKAP1,KDM3A,TBCEL,USP22,AKTIP,FBXL16,PIK3R5,ELFN1,NLRP3" Coexpression M8264 Genes up-regulated in B lymphocytes stimulated by anti-IgM: 3h versus 16h. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "DGCR6,CCDC85A,PCDH10,AMPD2,TMEM263,ARRB2,STK33,ATP6V0A1,SRSF11,MED24,OPTN,EBI3,MBNL2,TMEM35A,EML1,ADGRV1,POLK,USP16,SDCBP2,GAP43,RAB40B,GNAL,CNDP1,BVES,GUCY1B1,HNF4G,SOWAHA,KTN1,MAP4,CD200,ADAM22,SFR1,PDE1C,ZNF655,SPATA6,CNNM2,PXK,RAD52,MSANTD2,SATB1,LRRTM4,GALNT10,HSPA4L,DOCK10,RCOR3,SON,ZC3H13,NEK4,GANAB,ARC,SIRT1,DDHD1,TMPO,PDIA2" Coexpression M5302 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "TKTL1,ADD3,BBOX1,DGKD,MADD,CBFA2T2,CHN2,TCEAL2,CPS1,CRY2,DCAF4,NOS1AP,GPRASP1,RIPOR2,TBC1D5,USP3,RASGRP1,EEF1D,FAM13A,PLEKHA1,USPL1,RASGRP2,FCGRT,FYB1,GNAO1,LINC00667,IL11RA,ADAM22,MXI1,PCBP3,PCDHGC3,CDK14,PRPH,PTCH1,RAD52,C1orf54,ZNF331,SGK1,TTC17,PDZD2,ZBTB43,RAP1GAP2,MCF2L,ATMIN,PSD3,KAT6B,VAV2,WNT7A,GDPD5,TUBA1A,MPPE1,MARCH8,ZNF37BP,NLRP3" Coexpression M6404 Genes down-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (6h). MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ALS2,PHYHD1,ATP1A2,B3GALT2,FOXK1,MAP4K4,ANKRD44,ABCG1,MYADM,CD99L2,RPS6KL1,NR1D2,EPB41L2,RASGRP2,SLC43A2,MRPL10,TLR7,FGF13,PDLIM5,SARAF,TUBGCP4,CNDP1,FUT10,STON1,GRK4,VWA5A,PDE4A,GNG2,NLGN3,PIK3C2A,MINDY2,SUSD4,PRR5L,SEMA6D,SGK1,ANKRD6,SLC9A5,ABTB1,CDK19,SS18,ST5,FCHO1,ACSBG1,SYP,DNMBP,TP53BP2,NDRG4,MKRN3,SH3GLB2,PRDM2,PLSCR4,JMJD1C,ZDHHC20,SNX14" Coexpression M3314 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ARID1A,FMNL2,TMCC3,KIDINS220,LCORL,NT5C3B,MIER1,CASK,BTK,CDK5R2,PTBP2,CD81,FAM189A2,COL9A3,ARHGEF10,CSNK1E,RABGAP1L,USP3,CD99L2,LPAR6,TMEM35A,CEND1,ARMCX1,CORO2B,MEX3B,OGA,FYB1,CHL1,GRIK2,GABARAPL2,RBPJ,MYL3,ETFRF1,PRKCB,PTCH1,PEX5,RIPOR1,BEND5,RFX5,MRAP2,FBXW7,SEC14L1,HSPA4L,SH3BP2,R3HDM2,SLC12A4,ZNF667,DIP2A,ABCC8,FBXW11,TCF12,TIAM1,TP53BP2,SENP7" Coexpression M3222 Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells activated with lamina propria dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ARRB2,BCS1L,PROM1,RCBTB2,MAP4K4,CP,HAPLN1,CRYBB1,OSBPL3,GALNT9,PPP6R2,GUCD1,SRGAP3,LPAR6,CDKL3,ECSIT,EZH1,FCGRT,ATP13A4,GABRA5,MSL3,GPR22,RAPGEF4,NR3C1,BVES,ATXN2L,ARHGAP36,SOWAHA,INPP1,SLC35G1,CDH20,STXBP5,PIK3AP1,NAT8L,NHLH1,NTRK3,PLTP,HYDIN,GDPD1,RAB3A,RPE65,PRR5L,LRFN5,ST8SIA1,SORCS3,KIF21B,LHPP,SYNE1,TSN,LRTM2,KCNT2,LYPD6,CELF4,SLC38A1" Coexpression M8383 Genes up-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "TKTL1,SLC12A5,APOC1,CHRD,CCDC181,B3GALT2,PPT2,VCAN,CTNND1,CTNND2,DAPK3,IP6K1,ECM2,FCGR3A,KAT8,RASL10A,GABBR1,GBX2,GCK,MSTN,AHDC1,GJB1,GSTM5,IGF1,KLC1,LSS,MYH6,NCAM2,NCF2,NEUROD2,OGG1,PCSK1,PDE3B,PPARA,KHDRBS2,RLBP1,ROBO1,SALL1,FRMPD1,CPEB3,SLC2A5,SLC8A2,SLCO1A2,CAND2,NPAS3,DDN,SYT11,CDH22,NACC2,TMOD1,TPM1,TSC2,TTPA,VIPR2" Coexpression M5019 Genes down-regulated in comparison of plasmacytoid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "TMEFF1,ASCL1,CCDC181,SGCE,BAIAP3,CBS,SCARB1,CDC27,CDH2,NMT2,CLTB,CNGA3,AKAP6,NECTIN3,CTNND1,PHYHIP,BRINP1,EIF4G1,ERBB4,FGFR1,IP6K2,FOXO3,FOLR2,DENND2A,NCKAP1,SIGLEC8,GART,TUBA8,SPIN1,RAPGEF4,PRDM5,IL1RAPL1,ATXN2L,IFI16,KCNA2,KIF2A,NKX2-2,OGDH,PDZRN4,TNPO2,C19orf57,PTPA,PPP2R5E,C1orf54,LRRTM4,SHMT2,TMCC1,PDZD2,HECW1,GSE1,PRMT8,UGT8,WNK1,DNALI1" Coexpression M3409 Genes up-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 6 h after the stimulation. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "ABHD6,NDRG3,AMPD2,CNTNAP1,KCNAB2,SHTN1,ALDH4A1,ATP2B3,MTMR3,LDLRAD4,CLCN3,MYL6B,NMT2,DNAJB5,LY86,PICK1,SLC4A7,COX4I1,AATK,SPATA2,ECM2,LRRC17,RTN3,BAIAP2,NBEA,HBS1L,SESN1,CROCCP2,ITPKB,MEST,MYO7A,NINJ2,OGG1,PCDH8,PDE3B,SSH1,REV3L,KLHL11,SLC25A36,LGR4,RXRA,SATB1,SLA,PREX2,SNCA,ARHGAP26,CEP68,FAM168A,DNMBP,SATB2,PCDHGA1,ZMAT3,TMPO,ATP6V0E2" Coexpression M7500 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) versus non-Tfh. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "SYN3,SORCS2,WDR35,CEP126,ARHGDIG,DDX3Y,INSYN2B,BTRC,CLDN10,KMT2C,RAB33A,BAG4,RNF14,OSBPL3,FAM169A,FGFR1OP2,LONRF1,PITPNC1,SNX29,EEF1A2,KMT5B,TMEM35A,TMEM74,SH3YL1,CAMSAP1,OGA,FYB1,TRAF3IP2,SRCAP,GRM3,LMO2,SHC3,SFR1,RC3H2,FAM184A,REV3L,CCDC25,PPM1E,KIF16B,MTERF2,ATF7IP,SPATA7,VPS13A,ANKRD12,SYNE1,FRYL,PRRT1,TNS1,TP53BP2,CDK20,MKRN3,ACTR3B,JMJD1C,ST8SIA2" Coexpression M9386 Genes up-regulated in day 40 memory B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "PLEKHH1,ANK2,BCAS1,IGDCC4,ARHGAP5,MPDZ,RGS9,CDH8,TBRG4,SLIT2,C2CD2,OSBPL3,CNTNAP2,PLCXD3,DTNB,EDN3,PLXNC1,EPHA5,EFEMP1,POLR1B,USP21,GABRG1,STARD3,PSRC1,GPM6A,GPR19,GRIK1,KCNC2,KCNJ3,MYBPC1,NAP1L3,NOVA1,CNTN3,GPSM2,FAM216A,FAT3,WDR25,RAD17,FIGN,ROBO2,SMTN,ZSCAN29,ADHFE1,TPCN2,TNS1,PPIL6,TTC3,EIF4ENIF1,ZIC1,CADM2,STOX2,SLC39A12,FXR1,SOCS4" Coexpression M7548 Genes up-regulated in double positive thymocytes: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "EMILIN3,KIDINS220,ARNTL,CADPS,B3GALT2,LINC00847,SLC25A14,TJP2,AKAP6,MYRIP,PHACTR3,MYADM,FSD1L,OPTN,DCTN4,AMOTL2,ZNF559,SYT17,KCNMB4,GRB10,SERP2,IFI16,KLC1,NCOA7,LSAMP,MAP2,IL17D,SRSF12,MYO5A,NAP1L2,LRP12,GDPD1,TUG1,ROGDI,HKR1,ZNF671,ELMOD1,ZFP2,KIF21A,WDR47,NAPB,LMBRD1,SSTR2,SYT1,TRIM2,PCDHB6,PCDHB3,FNDC5,TUBB2A,TSPAN11,ZNF711,ZNF177,CASC15,JPH3" Coexpression M7489 Genes up-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-05 2.33E-01 4.82E-04 4.79E-03 54 200 "NDRG3,ADCY6,HACE1,OSBPL8,AMPD3,EPB41L5,GPAM,DPY19L3,NIPA1,CBFA2T2,OSBPL3,PITPNC1,YAF2,SH3GLB1,PLXNC1,EPB41,SH3YL1,SCML2,ATP8A1,GORAB,MED12L,FHL1,NBEA,NCKAP1,GHR,RAB40B,GRB10,SYTL4,GPR155,PPM1L,SESN3,MYCN,NAP1L3,NFIA,EPDR1,PTK2,ZIK1,SOX6,ITSN1,CPEB4,TNIK,ZBTB43,TROVE2,SEPT8,GSE1,PSD3,FRYL,SIK3,ZMAT3,TGFBR3,TJP1,BEX4,CCDC136,SPIRE1" Coexpression M9100 Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 [GeneID=22807]. MSigDB C7: Immunologic Signatures (v6.0) 2.05E-05 2.37E-01 4.87E-04 4.84E-03 46 162 "TKTL1,ADRB2,SORCS2,SPOP,CARNS1,AMPD3,ADAM15,CACNA1E,EVI5L,ANKRD44,CSF3R,RIPOR2,CD99L2,SRPK3,RASGRP2,STX2,RCSD1,IQGAP2,MSTN,RAPGEF4,PADI2,HP,KCNA2,KHK,NCOA7,GPR155,MATK,AQP11,SLC25A23,TATDN3,DEF8,PTPRE,TUG1,EMID1,MYO18A,ST6GAL1,ST3GAL3,SLC14A1,ELMO2,KIF21B,SULF2,FAM168A,CLASP1,CDK20,CELF4,SPIRE1" Coexpression M2582 Genes up-regulated in the HSC non-supportive stromal cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.05E-05 2.37E-01 4.87E-04 4.84E-03 46 162 "ABHD6,CEP126,AMPD3,ALDH7A1,CA12,SYNGR3,CHN2,JAM2,SLC4A8,CREB5,FEZ1,ATRNL1,ARNT2,DMPK,LPAR6,DNAJC27,PRKAG2,PRELID3A,MFSD2A,ATOH8,DDX19B,ICA1,BRINP3,SLC35G1,HECTD2,SCAMP5,RCOR2,OLR1,PCDH9,PDE3B,GDPD1,PTPN13,PTPRG,FOXRED2,PREX2,UNC5B,ARHGAP26,ELOVL4,ACSBG1,PLCB1,WWC1,TCF7,PIK3R5,RUNDC3B,WNK3,ADAMTSL3" Coexpression M2388 "Transcripts in hematopoietic stem cells (HSC) which are trans-regulated (i.e., modulated by a QTL (quantitative trait locus) not in a close proximity to the gene)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.06E-05 2.39E-01 4.90E-04 4.87E-03 182 882 "ABCF1,CLK4,ARID1A,ADCY6,AXIN2,NR0B1,AK2,ALK,ANXA7,CNTNAP1,PDXK,ASCL1,NUMB,ATP1A1,SLC4A4,MPDZ,RGS11,HCN2,BID,PROM1,CACNA1G,DDR1,CANX,SLC25A14,CDO1,NOG,CNOT8,TPP1,NMT2,CP,CHD1L,CRY2,RNF14,HINFP,CSNK1E,PDE4DIP,SDC3,CTNND1,GPSM1,MATR3,SIRPA,B3GAT3,MED24,SEC16A,DLG3,NR1D2,DMTF1,DUSP9,GOLT1B,EDN1,EDN3,ANKRD46,RASA4,ASB3,SORBS3,SRRM1,PIPOX,RTN3,CD320,FCGR1A,FDFT1,PRMT5,FGFR1,AMOTL2,HPCAL4,FOXG1,SYT3,SORBS1,TPK1,ATP6V1H,GFRA1,USP19,ZNF276,GLUL,GNAS,GRIA1,GRIK1,GRIK5,GRIN2C,GRIN2D,GSTT2,GYG1,HMGB1,IGFBPL1,AGFG1,HSP90AA1,IRF8,BTBD17,RBPJ,HES5,IL6ST,ITGAV,KCNA4,KCND2,KCNQ2,KIF5C,KIFC3,KLC1,LMO1,SMAD1,MBP,MMP17,MOBP,MSR1,MYO5A,MYO6,NAP1L1,NCAM1,NEFM,NEK1,NFIX,NPPA,SETD4,OGDH,PAK3,PBX1,PCSK5,PDE1A,PIK3CD,PIK3R1,SNX10,PMS2,MAPK7,WBP1L,ELOVL2,ZIK1,EML5,PTPRN,PEX5,RAD17,RAD52,RNH1,RTKN,MAPK12,SEMA6D,SCN8A,FOXRED1,SH3BP2,ITSN1,FHOD3,ST6GAL1,SLC12A4,EFHD1,ZKSCAN3,SNCB,SOX2,SOX15,SP4,STAU1,PHLDB1,KLHL7,ABCC8,PLCB1,TCF4,KIAA0930,CUX2,TNS2,FRYL,TEK,DICER1,AKTIP,MTMR14,TIE1,NACC2,CBX5,WBP2,NR2C2,ZMYND8,UBTF,VAV1,VLDLR,TBC1D15,WIPF1,WNT7A,NPDC1,REEP1,SMARCAD1,RNF103,TUBA1A,FZD3,ST7,FXR1" Coexpression M8696 Top 40 genes from cluster 7 of acute myeloid leukemia (AML) expression profile; 61% of the samples are FAB M1 or M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.07E-05 2.40E-01 4.92E-04 4.88E-03 14 28 "ANK1,CLCN3,GAPVD1,DNAJC6,EPB41,KCNH2,RAP1GAP,SLC6A8,SLC6A9,SPTB,TAL1,TNS1,TPM1,OSBP2" Coexpression 20937356-TableS1 Rat Hypothalamic_Mansuy10_1270genes GeneSigDB 2.17E-05 2.52E-01 5.14E-04 5.11E-03 184 894 "ABAT,NDRG2,ADCY5,PNMA8B,ZNF608,SNX32,HECW2,PLA2G6,C1QTNF1,SRPX,ARHGAP20,GPRASP2,APBB1,GAS7,APP,SHROOM2,ASGR1,MARCH3,RASL11B,ATP1A2,N4BP2L1,BMP7,RUNX1T1,UBE2L6,TAOK2,CLU,FADS2,AKAP7,MAGED1,IFFO1,CNRIP1,CP,ENTPD4,GDA,CLIP3,CST3,GPSM1,FAM131B,ECE2,DCAF8,RASSF2,DAPK1,SIRPA,HEPH,ELMO1,SRGAP3,ARNT2,CHRDL1,DLG2,DLG4,CDON,RCAN1,FIS1,EBF1,EDNRA,EDNRB,CNNM1,SIDT2,IRAK4,ING4,ENO2,RCAN2,RASL12,CD320,EZH1,FAM198B,ACSL4,CHST15,FCGRT,FGR,FHL1,SCARA3,SEMA6C,FOXO3,ERGIC3,SARAF,BRSK1,DKK3,GAB1,FAM120B,STARD10,SESN1,GGT7,GLI2,GLRB,OS9,GRIA2,GSTM5,ATOH8,IRAK3,HP,CPT1C,JAK2,KCNJ16,LIFR,LIG4,LMO2,LSS,SMAD9,MAOB,LYPLAL1,MGAT3,MN1,MOV10,CD200,SESN3,CCDC80,MSI1,NPR2,NPTX1,SLC11A2,PBX1,PDE4B,PDGFRA,PENK,FXYD1,SEPT4,POU6F1,PCDHB17P,MASP1,CNNM2,BCAS3,LAMA1,GDPD2,PTCH1,PXK,RAB5B,FAT4,OXR1,GAL3ST4,ROBO1,ROBO2,PCMTD2,TMEM100,PLPPR3,RXRA,SALL1,SEMA6D,SCP2,PEAR1,MAGI3,ST6GAL1,ST3GAL3,YPEL4,OGDHL,IFT122,PDZRN3,WDTC1,ZCCHC24,MYCBP2,UNC5B,LHPP,ST5,ADHFE1,SULF2,FAM168A,RHBDL3,CAMTA1,OBSL1,CYB561A3,ZFPM2,TGFBR3,SLC44A1,THRA,GZF1,TMEM9,KCTD2,TPM1,IL34,SYNPO2,SSBP2,FLRT2,PLEKHH2,CCDC136,PORCN,NPDC1,ZIC1,ZIC2,ZBTB16,RGMA,SEMA3B,ITM2C,PARP11,FBXO36" Coexpression M2794 "Genes down-regulated in retina cells from CRX and NRL [Gene ID=1406, 4901] double knockout mice." MSigDB C6: Oncogenic Signatures (v6.0) 2.18E-05 2.52E-01 5.15E-04 5.11E-03 39 130 "ADRB2,ASPH,DDX3Y,SGCE,CAMK2B,CCKBR,MFSD4A,NECTIN3,GREB1,GSDME,ABCC9,EYA1,FABP7,NSG1,GABRA2,GABRA3,SALL3,CPLX2,GGT7,NTNG2,INSM2,GRIK2,HES5,CDH20,KIF5C,IL17D,PLEC,TNPO2,ELOVL2,PTPN13,PYGM,RASGRF2,RXRG,LRRC4,DNAJC9,KAZN,WWC1,HRASLS,FRMD6" Coexpression M1110 Up-regulated genes from the set A (Fig. 5a): specific to cells expressing MLL-AF4 [GeneID=4297;4299] fusion protein alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.22E-05 2.57E-01 5.24E-04 5.20E-03 52 191 "PCDH19,ANK3,APC,JAM2,CNRIP1,GDA,ARHGAP32,TCAF1,MATR3,GIT2,GSDME,DTNA,EBF1,OLIG2,WAC,ST3GAL6,FLT1,B3GAT1,BRD8,GK,TNRC6A,TDRKH,NR3C1,KAT7,SCRG1,TUBB2B,MARK1,ERICH3,MYO5A,NAP1L3,NCAM1,PRTG,PFKFB2,SH3KBP1,SETD5,TMEM206,RPL15,ADAL,WLS,CLSTN1,WDR37,BTBD7,ANKRD28,TRIM2,GPRIN3,NR2C2,WIPF1,TRIM9,NAV3,PAK5,JMJD1C,ZDHHC20" Coexpression 16273092-TableS1b Human InVitro_Bild06_298genes GeneSigDB 2.27E-05 2.63E-01 5.34E-04 5.31E-03 61 235 "HACE1,ADGRB2,NIPA1,DIS3L,B4GALT6,ABCG2,RAB26,TMEM155,LRIG1,ATRNL1,TSPAN5,EEF1A2,PCOLCE2,USPL1,ENO2,CEP78,FGFR3,CAMKK2,KHDRBS3,CSPG5,GLRB,KDM2B,GNAL,GNAS,TPPP,PSIP1,UBE2QL1,METTL21A,TM6SF1,KCTD6,NASP,TMOD2,PFKFB3,RETREG1,KCTD15,EPB41L4B,PTCH1,RAVER2,SCN8A,IL17RB,MRAS,SH3BGR,FERMT1,GKAP1,KDM4B,PEG10,CDK19,STXBP1,GSE1,DNAJC9,SIN3B,TIAM1,HEY1,UGT8,LYPD6,REEP1,EML6,ZNF195,SLC30A4,PHTF2,NETO2" Coexpression M4680 "Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.32E-05 2.68E-01 5.44E-04 5.41E-03 65 255 "ABAT,ADD1,ALK,ANK1,ANK2,TMEFF1,ARRB1,MARCH3,BCHE,NRP2,ST3GAL5,MAP4K4,CREM,AKAP12,CSNK1E,JAKMIP2,GSDME,RHOBTB1,ABI1,E2F5,PLXNC1,LRRC17,EYA1,RASL10A,DENND2A,GAD1,GATM,PCDH17,MSL3,GPM6B,NR3C1,HMGCR,INPP1,DIPK1A,ITPKB,JAK1,KCNN3,VWA5A,SMAD1,MMP16,MN1,MYCN,NELL1,NRCAM,PCSK5,SERPINE2,PRRX1,MAGEL2,EPB41L4B,WBP1L,SPDL1,PTPRE,MORC4,STK32B,MEG3,SATB1,SCN3A,GALNT10,SGK1,SCN3B,NFASC,TCF7L2,DICER1,TPM4,CADM1" Coexpression M17794 Down-regulated genes associated with poor survival prognosis of patients with metastatic neuroblastoma that lack MYCN [GeneID=4613] amplification. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.34E-05 2.71E-01 5.49E-04 5.45E-03 19 46 "APBA2,SPTBN4,FUBP1,CACNA1G,HAP1,CNR1,FAXC,GPR85,TMOD2,ING3,PLPPR3,SCN3A,BTBD3,SMARCE1,SCN3B,DDHD2,CAMTA1,ST7,ST8SIA2" Coexpression M2910 Genes down-regulated in skin from INFG [GeneID=3458] knockout mice after injection of: control versus Trypanosoma cruzi (strain Y). MSigDB C7: Immunologic Signatures (v6.0) 2.37E-05 2.74E-01 5.54E-04 5.51E-03 40 135 "SLITRK1,DYNLL1,RUNX1T1,DIS3L,CP,DGKB,DGKG,EN2,COQ7,GART,GLRB,DIPK1C,GUCY1A2,SYNPO,CELF5,HTR2A,IRF8,IGSF1,KCNA4,KLRC2,LSS,AQP11,XRRA1,NEFH,OPRL1,CDK14,PKM,PMP2,RANBP3L,PTN,RFX5,KIF27,FERMT1,DDN,THSD1,SULF2,NECAB1,MLST8,BEX4,MAP3K12" Coexpression M15148 Genes down-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.38E-05 2.75E-01 5.54E-04 5.51E-03 34 108 "PRX,MPDZ,CLTB,CPEB2,FDFT1,FGF1,SEMA6C,GFRA1,GJB1,HMGCR,ITPKB,KCNK1,LSS,MBP,NRBP2,MT3,PCMT1,ABCB1,PIK3R1,PMP22,RAP1GDS1,SLC6A15,EMID1,RTN1,S100B,SCN7A,SIRT2,EFHD1,LIMCH1,SNCA,NACC2,UGT8,ZBTB16,SEMA3B" Coexpression M344 Genes up-regulated in plasmacytoid dendritic cells: IL3 [GeneID=3562] versus IL3 [GeneID=3562] and the HIV matrix protein p17. MSigDB C7: Immunologic Signatures (v6.0) 2.43E-05 2.81E-01 5.65E-04 5.62E-03 46 163 "RNF157,WDR35,B3GALT2,BLM,SYNJ1,ARHGEF7,MTMR2,AP1M1,TAOK2,ATRNL1,ARMCX2,DNAJC27,USP21,ZMYND11,TNRC6A,GRK4,DIDO1,KAT7,KCNA2,KCNF1,LYPLAL1,PFKP,RETREG2,VPS13C,RASGRF2,CASC3,SUPT20H,FNDC3A,R3HDM2,CCDC88A,NAPB,TTC17,USP33,WDTC1,CLUAP1,POGZ,TTBK2,ATP11A,DNMBP,SIK3,ZNF106,R3HDM1,SF1,DOCK8,RTN4,CPNE4" Coexpression 17875932-TableS4 Mouse Leukemia_Torchia07_928genes GeneSigDB 2.53E-05 2.92E-01 5.86E-04 5.82E-03 120 543 "NDRG2,TMCC3,C1QTNF4,PITPNM2,KCNAB2,CPNE5,PDXK,MARCH3,ZSCAN18,N4BP2L1,DOCK11,CD81,ARHGEF2,MAGI1,RCBTB2,CHM,TJP2,MAP4K4,HOMER3,CNN3,PCYT1B,SLC4A7,IFFO1,CREM,GDA,SOCS5,ZFYVE16,DOCK2,ARRDC4,KLHL5,FRY,OPTN,PLXNC1,LPAR6,EPS8,RCSD1,F5,SCML2,FDFT1,CAP2,NBEA,PDLIM5,TPK1,KHDRBS3,DACH2,ST6GALNAC3,FYN,BRPF3,IQGAP2,CPLX2,GCNT2,DCLK2,ADGRA3,GP1BB,TDRKH,GRB10,NR3C1,GSTT2,NCKAP1L,HLF,ACOT7,CPT1C,SOWAHA,FGFBP3,MAN2A2,MAPT,LYPLAL1,AQP11,TM6SF1,MEF2C,MEIS1,MEST,MYCN,PCBP3,PBX1,PDE3B,PDE4B,SMOX,SCHIP1,SEPT4,BCAS3,CNTLN,CASTOR1,SH3TC2,RNF220,NUDT11,ATP8B4,SATB1,ATXN1,ZFP2,SELL,FAM102A,PPP1R9A,PPM1E,DOCK10,MAGI3,NUBPL,SCMH1,NMNAT2,BEX1,ITPRID2,CEP68,RGL1,TBCEL,WDR7,DOCK9,ZMAT3,TGFBR3,TJP1,HEY2,BEX4,TPD52,RUSC1,SGK3,PDIA2,SLAIN1,WIPF1,SLC38A1,PLSCR4,RSPRY1" Coexpression 18927307-tableS3 Human Colon_Allen08_382genes GeneSigDB 2.53E-05 2.92E-01 5.86E-04 5.82E-03 58 221 "USP31,ADGRF5,PKP4,CACHD1,CDC14B,ATP1B3,DST,CAMK2G,KRIT1,MAGI1,MAP4K4,CHD1L,NCOR1,ARHGEF10,CTNND1,ZFYVE16,ZBTB24,USP3,CDON,FARSB,YAF2,MBNL2,ABI2,EIF4G2,PAN3,GPHN,DLC1,UBE2E3,DCTN2,ZMYND11,GART,GK,GPR75,NR3C1,AP4S1,MAP2,MBNL1,MBP,MID1,NRDC,FTO,PTPA,PPP3CA,PTK2,PTPRG,RFX3,SETD5,TMLHE,POGZ,ANKRD28,ATP11A,TCF7L2,WASHC4,ACTR6,DDHD1,TRIO,PITPNB,RTN4" Coexpression 12446012-Table1 Mouse Immune_Carmody02_20genes GeneSigDB 2.56E-05 2.96E-01 5.93E-04 5.89E-03 10 16 "CALM1,CST3,TUBA1B,GNAS,TUBA1C,MBP,MOBP,MT3,PLP1,TUBA1A" Coexpression M12004 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [GeneID=3065;3066] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.59E-05 2.99E-01 5.97E-04 5.93E-03 60 231 "GALNT16,PLEKHH1,MTUS1,KIAA1324,CADM3,CALB2,NOG,NRXN3,CLU,FADS2,CNRIP1,HAPLN1,RHOBTB1,DTNA,EBF1,EDIL3,ATL1,KATNAL1,F8,FDFT1,FGF1,FGFR1,SCARA3,CAP2,CSDC2,GLI2,PCLO,SYNPO,HMGCR,LSS,MATN2,MEIS1,MN1,SESN3,CCDC80,PDE1C,PPP2R2B,SYTL2,PTCH1,TMEM255A,FIGN,TMEM100,TCP11L1,SCN2B,TMEM200C,SPP1,BEX1,EPB41L3,TCF4,NACC2,TK2,TNS1,TPM1,SSBP2,HIRA,MGAT5B,LAT2,TUBA1A,SEMA3B,JPH3" Coexpression 18849563-SuppTable3b Human Lung_not_cancer_Bhattacharya09_220genes_FEV1/FVCinCOPD GeneSigDB 2.59E-05 3.00E-01 5.97E-04 5.93E-03 44 154 "ABHD6,CEP126,LTBP4,APBB2,RUNX1T1,CBLN1,LETMD1,DLC1,ATP13A4,ZNF44,ATF7,KIF3A,LRP1B,KITLG,MITF,MYT1,PRTG,FAT3,PPP3CC,GDPD1,PTCH1,RBBP6,GSTCD,ROBO1,SEMA6D,SH3GL3,ANKRD6,SLC2A5,SEPHS1,MTERF2,GKAP1,ZNF302,TMEM150C,DDHD2,TMEM136,ARHGEF12,KHDC1,UBTF,PLEKHH2,ZNF23,ZNF177,DNAH10,ZNF248,ZNF30" Coexpression 18849563-SuppTable3a Human Lung_not_cancer_Bhattacharya09_220genes_FEV1inCOPD GeneSigDB 2.59E-05 3.00E-01 5.97E-04 5.93E-03 44 154 "ABHD6,CEP126,LTBP4,APBB2,RUNX1T1,CBLN1,LETMD1,DLC1,ATP13A4,ZNF44,ATF7,KIF3A,LRP1B,KITLG,MITF,MYT1,PRTG,FAT3,PPP3CC,GDPD1,PTCH1,RBBP6,GSTCD,ROBO1,SEMA6D,SH3GL3,ANKRD6,SLC2A5,SEPHS1,MTERF2,GKAP1,ZNF302,TMEM150C,DDHD2,TMEM136,ARHGEF12,KHDC1,UBTF,PLEKHH2,ZNF23,ZNF177,DNAH10,ZNF248,ZNF30" Coexpression M2618 Genes transiently induced only by the first pulse of EGF [GeneID =1950] in 184A1 cells (mammary epithelium). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.62E-05 3.03E-01 6.01E-04 5.97E-03 347 1838 "ASIC2,ADD3,SORCS1,GRAMD1B,PTCHD1,SLC44A5,ZNF608,MTUS1,KLHL13,RTL9,OSBPL1A,SORCS2,DISP3,PLA2G6,BBOX1,FAM135A,KCNT1,MRTFA,LRCH2,ANK3,CCDC146,MAP4K3,USP28,CNIH2,KCNAB2,APBB2,GPAM,APOC1,CACHD1,APOC2,SLC7A14,SEMA4G,PPP4R4,TMEM263,RGS20,ARRB2,CDK13,ASPA,ATP1A2,MTMR9,N4BP2L1,ATP6V1G2,RIPK1,BBS2,CFLAR,PRMT9,C5,CACNA1B,DDR1,CAMK2G,ZNF501,USP6,USP2,C1orf52,MYOM2,KCNAB3,DCLK1,LGI1,TIGD7,CCPG1,CIART,FOXN3,CHN1,B4GALT6,C4orf33,TMEM155,COL4A5,TBPL1,NECTIN3,FAM171B,C2CD2,CREM,CREB5,TRIM69,CRYM,CSF1,LRIG1,LRRC3B,PDE4DIP,CNTNAP2,DZIP3,CTH,RIMS2,RUBCN,HDAC9,ARHGAP24,ZFYVE16,KIAA0586,DAPK1,KIAA0087,DNAL1,ARMCX4,SPATA2,DNAJC6,ZBTB24,HEPH,MYEF2,HP1BP3,CEP170,BLOC1S6,DLG2,SLC12A6,TOM1,ST8SIA3,SNX29,EDNRB,ANKRD46,EEF1D,FSD1L,CELSR3,RASA4,LPAR6,PLEKHA1,ING4,CERCAM,MRNIP,C8orf37,USPL1,EPB41L1,MTSS1L,SLC43A2,STX2,CDKL3,RRAGB,NRN1,F5,NSRP1,ZSCAN30,TESK2,FECH,FER,BAIAP2,EFCAB2,NBEA,POMT1,UFM1,USP21,ZNF512,FYB1,STAG2,GAD1,ZNF234,ZNF274,LRRC37A6P,BRD8,RAB30,GPR75,GNAL,PSRC1,GOLGB1,GPR37,GRK4,CNTRL,DIDO1,PLPP7,GSN,GSTM5,ZBTB49,BVES,AP4S1,PSIP1,GUCY1A2,WIF1,HPS5,ARHGAP19,MIER3,SYNPO,HSPA1L,HES5,INPP1,INPP5B,ZNF385B,KCNK1,CREG2,KIF5A,KLRC2,KLRC3,LIG4,VWA5A,MAP2,MAP6,MEIS1,KCTD6,MIA2,KITLG,MID1,POC1B,MN1,MOBP,MOV10,SESN3,CCDC80,BCO1,MSRA,TAGLN3,NAP1L2,NAP1L3,NFIA,NFE2L2,NKX2-2,SLC11A2,HCN1,KSR2,PBX1,PCSK5,CDK18,PDE4D,PDPK1,TMOD2,PFKFB4,SERPINI1,NALCN,PIK3R1,ZNF655,RETREG1,PLCD1,ZNF426,MTRF1L,PLXNB1,PLXNB3,C11orf49,LRP12,MINDY2,PPM1B,MIR124-2,PPP3CC,MAPK10,FITM2,PSD,WBP1L,SYTL2,GDPD2,ZSCAN32,PTPN13,FAM120C,ZSCAN2,ZNF615,ZNF844,RALGDS,FAT4,FAM184A,ARID4A,RFX5,RGS12,RNASEL,C12orf49,TMEM206,YY1AP1,PCMTD2,TMEM100,NEK11,FBXW7,TCP11L1,CNTNAP3,ABCA11P,CLIP1,CCDC112,S100B,DGLUCY,SEMA6D,ATXN7,SCN4B,SCN7A,FNIP1,NLGN4Y,ARX,CPEB3,ST6GAL1,SLC1A3,WDR47,SLC14A1,NAPB,ATF7IP,CPEB4,SMARCD3,INTS9,MBD5,KIF13A,CMTR2,SNRPN,TMCC1,UNC80,WDTC1,MYT1L,TRERF1,KDM3A,IDI2-AS1,LHPP,PBLD,COLGALT2,THSD1,ZC4H2,ZSCAN29,APOM,CEP68,ADHFE1,PHLDB1,NECAB1,MLC1,FGD4,JMJD6,SYNE2,PLCB1,SYT1,MMS19,KAZN,CAMSAP2,ADGRL3,AGTPBP1,TCF4,PSD3,FAM200B,TGFBR3,KCTD2,KAT6B,TP53BP2,LRRC24,TUBB2A,AMOT,GORASP1,PITPNB,FLRT2,TOM1L2,SLC47A2,ZNF23,ZNF28,ZBTB16,SYNC,INTS3,PMEPA1,MAP3K12,EMSY,RNF103,NAV3,NAV2,TRIM16L,PLSCR4,AMN1,DOCK8,MARCH8,ZNF37BP,FBXO36,JMJD1C,VANGL2,RNF146,GAN,SENP7" Coexpression M18841 The 'MLL signature 1': genes down-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to all AML cases with the intact gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.62E-05 3.03E-01 6.01E-04 5.97E-03 62 241 "AP1B1,BIN1,APP,AQP4,WASF1,MYRF,BAIAP3,CFAP410,CA4,HIP1R,RUNX1T1,PPT2,CHD1L,CLIP3,SIPA1L1,PPP1R16B,ST18,DAPK1,ELMO1,CEP170,EEF1D,EGR3,DLC1,FDFT1,TRIM16,RASL10A,ATP2C1,ZNF274,GGT5,BRD8,HPGDS,HLF,ITGAV,JAK1,CD200,NBL1,NOVA2,CYTL1,OLA1,ABCB1,SERPINE2,TNPO2,SIDT1,RIPOR1,GTDC1,NUDT11,BAALC,STK32B,ASAP3,SLC12A4,SOX11,ZSWIM8,MCF2L,TAL1,TIE1,TPD52,TRH,ZMYND8,TTC3,DNAJC12,PITPNB,SLC13A3" Coexpression 20145155-TableS2 Human StemCell_Lottaz10_24genes GeneSigDB 2.64E-05 3.06E-01 6.03E-04 5.99E-03 12 22 "ASCL1,ELAVL4,CSPG5,DLL3,SYT17,GRIA2,KCNQ2,MARK1,BCAN,SOX11,ARC,SEZ6L" Coexpression 15750623-SuppTable1b Mouse Brain_Johansson05_23genes GeneSigDB 2.64E-05 3.06E-01 6.03E-04 5.99E-03 12 22 "FAM131A,ATP2A2,SYNGR3,CHN1,CALY,CTNND1,PPP1R1B,ACOT7,PPP3CA,PRKCZ,RPH3A,SLC30A3" Coexpression M4687 Genes down-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] CXCR5+ [GeneID=643] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.66E-05 3.08E-01 6.06E-04 6.02E-03 53 197 "ACTN1,SFMBT2,PPP4R4,LINC00173,MARCH3,BBS2,PTBP2,LARGE1,CHI3L2,CCDC144A,C8orf34,KLHL3,SEC16A,E2F6,SNX29,PAN3,ERBB4,KCNK1,KCNQ3,HECTD2,LOC100128239,LYRM9,NAP1L3,IDNK,NEUROD2,SLC11A2,PCSK5,PIK3C2A,RETREG1,FAT3,DRAM2,MAPK8,C1orf54,FAM184A,GAL3ST4,RIMKLA,FAM19A1,SEPHS1,GKAP1,KIF13A,CAND2,MYCBP2,BEX1,SPART,SSBP2,XRCC4,ZNF23,LOC100506497,C12orf4,GOPC,CERS6,ACTR3B,KLHDC1" Coexpression M3118 Genes up-regulated in comparison of naive T cells versus memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.66E-05 3.08E-01 6.06E-04 6.02E-03 53 197 "METAP1D,KLHL13,GPRASP2,PITPNM2,APBA2,APBB1,SFMBT2,TMEM263,SLC2A11,DDR1,SCARB1,CHI3L2,GPRASP1,SNPH,ARMCX2,KCTD3,SCML2,FCGRT,NBEA,RAPGEF6,ADGRA3,ZNF496,BACH2,HSF2,ZNF546,MEST,DNHD1,SLC11A2,NUCB2,PCSK5,PDE3B,SERPINE2,PIK3CD,RETREG1,LRRN3,CEP41,TUG1,BEND5,GAL3ST4,RGS10,SATB1,BTBD3,SORCS3,SNRPN,ZC4H2,ROBO3,RNF175,PRRT1,ZMYND8,TOM1L2,CIAPIN1,AMN1,KLHDC1" Coexpression M1760 Genes down-regulated after Cre-lox knockout of LSD1 [GeneID=23028] in pituitary. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.71E-05 3.13E-01 6.14E-04 6.10E-03 17 39 "CHGA,CHGB,RIMS2,RIMS3,DLL3,CPLX2,PCSK1N,PCLO,PCSK2,RAB3A,SNAP25,STXBP1,SYN2,SYT1,SYT4,CHST8,TRO" Coexpression M1797 The glioblastoma multiforme (GBM) plasticity signature: genes down-regulated in neural stem cells (NSC) with double knockout of TP53 and PTEN [GeneID=7157;5728] vs those with knockout of TP53 alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.72E-05 3.15E-01 6.14E-04 6.10E-03 22 58 "NDRG2,CADPS,CLU,COL9A3,PCOLCE2,EPHB1,EFS,ATP8A1,PSD2,PADI2,ITGA7,KCNA6,LSAMP,MAPT,ZDHHC14,RNASE1,PCMTD2,DRAXIN,DZIP1,SYN2,DDHD1,TST" Coexpression 19523942-Table2 Human Brain_Potter09_64genes GeneSigDB 2.72E-05 3.15E-01 6.14E-04 6.10E-03 22 58 "TTYH1,SERPINA3,BBOX1,ASCL1,CRMP1,RASSF2,SPOCK2,FABP7,OLFM1,GDF1,GFAP,GPM6A,NBL1,PFKP,PMP2,PTPRZ1,RGS4,RNASE1,S100B,ABLIM3,SNAP25,SYT11" Coexpression M3335 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.73E-05 3.16E-01 6.15E-04 6.11E-03 77 317 "ABAT,APLP1,SHTN1,CDK10,TMEFF1,ALDH4A1,ADAM15,CACNA1G,WASF1,MYRF,BAIAP3,SPAG9,CLTC,SLC4A8,AKAP12,PDE4DIP,TCAF1,DAPK3,DBN1,DNM2,SEZ6L2,AASS,CDKL3,TAOK3,FER,KIAA1109,FHL1,SORBS1,CGREF1,CYP46A1,GLYR1,STARD3,PCSK1N,GPM6A,GSN,HBA1,MAN1B1,TUBB2B,ITGA7,KHK,L1CAM,MEF2C,NCAM1,NRGN,ENPP2,SERPINI1,PIK3CD,GPSM2,PLEC,SEPT4,PRKCB,PRPH,RADX,NUDT11,SBF1,SH3GL3,PPM1E,ANKRD6,SLC6A8,SMARCD3,IFT122,ZCCHC24,ZSWIM8,PEG10,ZBTB43,ACSBG1,SYT11,CAMTA1,DOCK9,ATP13A2,BEX4,RUNDC3B,TST,SGK3,PLPPR2,TUBA1A,SLC17A7" Coexpression M3019 Genes up-regulated in 3 out of 4 NSCLC cell lines (non-small cell lung cancer) after treatment with azacitidine [PubChem=9444] and TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.86E-05 3.30E-01 6.43E-04 6.38E-03 50 183 "TKTL1,APBB2,DGKZ,ATP6V0A1,RGS9,SYNJ2,BAIAP3,SPAG9,REPS2,CDO1,CLGN,NMT2,CLTB,IFFO1,AKAP12,SLC12A6,OPTN,ENO2,RASGRP2,FHL1,FLNC,CGREF1,GLS,FERMT2,KLF12,HSD17B1,TUBB2B,LIFR,MKLN1,MT3,NNAT,NPTX1,NRGN,OXTR,SERPINI1,PIK3CD,PRKAB2,TTLL7,SEC61A2,ZNF331,SMPD3,SLC6A8,RBM34,NXT2,SYT11,DNMBP,TRIO,TUBB2A,LAT2,PMEPA1" Coexpression 17597811-SuppTable7 Human Leukemia_Mullighan07_566genes GeneSigDB 2.88E-05 3.33E-01 6.46E-04 6.42E-03 108 480 "ACLY,ADAR,AK2,LTBP4,ALK,DGKD,DDO,FAM131A,AQP4,CAPRIN2,ATM,CFLAR,CDK5R1,DST,CACNA1I,CA12,CACNA2D1,CAPN3,RUNX1T1,CHGB,TJP2,NIPBL,HOMER3,CNR1,WHRN,COL4A5,ABCG1,CS,SIPA1L1,DZIP3,PPP1R16B,CTH,DGKG,SCRN1,IP6K1,FEM1B,EEF1D,FRY,MBNL2,KMT5B,LPAR6,PLEKHO1,FGFR1,FHL1,FOXO3,PDLIM5,CAMKK2,CELF1,STAG2,GAD1,ARFIP1,PPARGC1A,GK,GPM6B,MCHR1,KIF3A,RNFT2,GUCY1B1,HMGB1,AGBL5,HSP90AA1,LAMA2,LIMS1,MAN2A2,MEIS1,CD200,NBL1,NCAM2,NFE2L2,CNOT4,PCDHGC3,PDE2A,PDE3A,PDE4B,PDE4D,SNX10,RETREG1,SCHIP1,POU6F1,PKN2,PSMA6,APTX,SNRK,SPDL1,LGR4,RYR1,ASRGL1,SH3BP2,FHOD3,ARHGEF40,SLC15A2,SMARCD3,SON,EMC1,SPTAN1,ZBTB43,SRPK2,SEPT8,ZFR2,IQCE,TCF7,DOCK9,TMPO,CHST5,KCNE5,TST,SH3GLB2,WNK1" Coexpression M6751 Genes up-regulated in splenic dendritic cells versus 33D1+ B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.92E-05 3.38E-01 6.54E-04 6.50E-03 43 150 "PLEKHG5,SYT13,CDC42BPA,ATP6V0A1,RIPK1,CCKBR,CD38,FOXN3,CP,NECTIN3,EDNRB,PCOLCE2,CALCRL,ATP13A4,FLYWCH1,FOLR2,NPTN,SARAF,GGT5,RND1,GSTT2,ADAMTS6,VSIG4,DDR2,NUCB1,OMG,P2RX7,POLG,NDUFS7,MTMR10,FEZF2,BSDC1,RNASEL,LGI2,ST6GALNAC6,SLC30A10,PPM1E,SCN3B,PEG10,ATP10B,WNK1,RTN4,FRMD6" Coexpression M9032 Down-regulated in MCF7 cells (breast cancer) by TLX1 (HOX11) [GeneID=3195]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.02E-05 3.50E-01 6.77E-04 6.72E-03 52 193 "SERPINA3,RNF150,ALCAM,AMPH,PDE8B,PTCH2,BMP7,JAZF1,RUNX1T1,LOC730101,CLGN,ARHGEF4,SHANK1,EML1,ERBB4,FAM198B,FGF11,FGF12,FGF13,DKK3,GAD1,TOX3,GPER1,GUCY1A1,LINC01102,KCND3,KIF5C,MATN3,LRP1B,MYCN,NELL2,CDK14,SPATA6,PKIA,DIRAS2,LRRC49,FIGN,MCMBP,SYNDIG1,WLS,SGK1,SLITRK3,PREX2,SLC8A1,INAVA,TNIK,UNC5B,BEX1,PSD3,LEFTY2,HHIP,CADM1" Coexpression M8161 Genes up-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 3.10E-05 3.58E-01 6.92E-04 6.87E-03 53 198 "RALGAPA1,NME5,PARG,APOC1,APOC2,ADGRB2,BAIAP3,THSD7A,USP2,INA,CDH2,DCLK1,LOC730101,FHL5,FEZ1,OSBPL3,SPATA2,PLEKHA1,VPS13B,ERBB2,EZH1,ARMCX1,DENND2A,GFAP,ADAMTS8,KLRC3,MYL3,NCAM2,NELL2,OGG1,OPA1,MARCH1,RAD17,SEMA6D,CCDC92,PREX2,SOX3,SOX11,TSPYL2,PJA1,MCF2L,FAM208A,WWC1,FBXW11,PSD3,TEK,LEFTY2,TLL2,PORCN,SPHK2,ZNF154,ZSCAN26,JPH3" Coexpression 17823660-TableS2 Human Viral_Urosevic07_495genes GeneSigDB 3.15E-05 3.64E-01 7.02E-04 6.98E-03 102 449 "SRPX,BBOX1,ANK2,DYNLL1,DST,BTRC,CA12,DDR1,MAP7,CBR1,CD86,CDC42,LARGE1,UBE2L6,CLTB,LY86,ARHGEF6,MYRIP,CP,ENTPD4,CSF2RA,FEZ1,PLCH2,PDE4DIP,CTNND1,SNPH,KIAA0513,DAPK1,CTIF,HEPH,RHOBTB1,SV2B,CHRDL1,DNM1,GNE,ECM2,DNAJB6,EIF4G1,EIF4G2,TENM1,TNK2,ELN,EML1,LRRC17,RASGRP2,NCALD,CDHR1,F5,F8,ABCA8,TESK2,FGFR1,FHL1,FOLR2,KHDRBS3,ADAM28,GPD1,GPER1,STMN2,GSTM5,PADI2,HMGCR,IFI16,IGF1,IL11RA,INPP1,TUBB2B,ITPKB,LAMA2,LMO1,MAP2,MAP4,MT3,MX1,MYO7A,NOVA1,NTRK2,NTRK3,PAH,CDK14,PLIN1,PPP2R5E,RELN,PTHLH,PTH1R,PTPN13,PTPRZ1,RNASE1,MEG3,RTN1,ST8SIA1,CAND2,ZNF423,ATP10B,ANKRD28,TNNT1,TPM2,ZMYND8,HIRA,UBC,AMOT,VSNL1" Coexpression M433 Genes up-regulated in neutrophils isolated from: healthy versus patients with peridontitis. MSigDB C7: Immunologic Signatures (v6.0) 3.20E-05 3.70E-01 7.12E-04 7.07E-03 39 132 "CSMD2,PPFIA4,PPFIA3,CPNE5,CACNA1G,CACNG1,RASGEF1C,TMCC2,RASL12,EXTL1,CYP46A1,GJB1,FRMD3,KLHL23,PACRG,MDM4,BCO1,NELL1,VWA2,GPR88,OXTR,GNG2,PNMA3,NXPH1,RAD52,ENOX1,CCDC112,SOX6,SLC6A7,TMEM132D,RIMS1,SOX2,MESP1,TAL1,CADM1,RPRM,P2RY12,ZBTB16,TMEM163" Coexpression M16859 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC3 [GeneID=8841] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.22E-05 3.72E-01 7.15E-04 7.10E-03 118 535 "ELFN2,ADD3,OLMALINC,KIAA1324,ALCAM,MARCH4,PKP4,DGKZ,LRRC4C,PDXK,NCOA1,ADGRB2,BARD1,RGS9,HIP1R,CBS,SEPT7,CDC42,ZMYM4,DIS3L,CFL2,TBPL1,TCEAL2,NCOR2,CTH,RIMS2,TCAF1,CTIF,AIF1L,GUCD1,DNM1,CD99L2,GNE,DTNA,EDN1,FEM1B,EBI3,RASA4,DCTN4,MFSD10,MTSS1L,FGF1,FGF11,SCARA3,EFCAB2,UFM1,PNMA2,GABRB3,BRPF3,GAP43,ZNF559,GCNT2,C1QL1,TOX3,PSRC1,NUDT21,PCLO,SYNPO,SCIN,MATN2,MITF,MN1,MOV10,NFIA,OTOGL,NME4,ENPP2,SLC25A23,PSAT1,DRAM2,CEP41,UHRF1BP1,PEX2,TUG1,TMEM255A,FIGN,TCP11L1,ST6GALNAC6,SARS,CASC3,GALNT10,EPN2,SEPHS1,SMARCC2,OGDHL,LIMCH1,SNCA,TMCC1,ZCCHC24,TEX2,BEX1,CDK19,NFASC,EPB41L3,PDLIM2,ATMIN,TCF4,KIAA0930,SYNE1,OBSL1,SPX,ITGB3BP,FBXL16,NACC2,PARD3,TNS1,TPM1,TPM4,TRO,MGAT5B,VGF,LAT2,XRCC4,ZNF70,GDPD5,SEMA3B,MARCH8,VANGL2" Coexpression M10311 "Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 6 h time point that were not down-regulated at the previous time point, 4 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.24E-05 3.75E-01 7.19E-04 7.14E-03 45 160 "BACH1,CFLAR,ARHGEF2,TJP2,CREB5,HDAC9,YTHDC1,ZBTB24,FBXL5,ARNT2,DMTF1,FRY,EPB41,ETV1,AMOTL2,STAU2,ZNF44,GLI2,STON1,GRIK3,NR3C1,GRM8,ICA1,ITGAM,SMAD1,MEIS1,MN1,NAP1L3,PIK3R1,SCHIP1,PCMTD2,RPE,SCAF8,SGK1,SLC22A4,DOP1A,TROVE2,CEP68,KANK1,FAM168A,ANKRD28,TCF7L2,TRIM2,ZNF24,PRDM2" Coexpression M2239 Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.26E-05 3.77E-01 7.22E-04 7.17E-03 80 334 "AXIN2,OSBPL8,AK2,ALCAM,ZFYVE28,CDK13,ASPH,DST,FUBP1,CAMK2D,RAB28,RCHY1,NECTIN3,CREM,ARHGEF10,SOCS5,DOCK4,TCAF1,TOMM20,TSPAN5,FSD1L,SRRM1,GORAB,SEC24B,CAP2,SYNCRIP,ATP2C1,GCNT2,TCERG1,GLS,NUDT21,NR3C1,RASSF8,ELOVL5,AGFG1,RBPJ,IPO5,MAP2,MBNL1,COMMD5,NFYA,OPA1,XRN1,PPP2R5C,PPP2R5E,PPP3CA,PTK2,PTPRG,C1orf109,RAP1GDS1,OXR1,FIGN,ZNF532,SFPQ,SEPHS1,LIMCH1,KIF13A,TRERF1,MYCBP2,RBM26,TROVE2,VPS13A,POPDC3,AGTPBP1,NR2F1-AS1,EHBP1,DOCK9,SLC44A1,CBX5,TMPO,RBFOX2,RUNDC3B,SSBP2,UBE3A,WIPF1,ZNF184,HNRNPA3,MSRB3,FXR1,FRMD6" Coexpression M2143 Genes down-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.29E-05 3.81E-01 7.27E-04 7.22E-03 35 114 "AMPH,MYRF,LDLRAD4,CP,PHACTR3,BOC,HDAC9,SNAP91,AK5,CCDC3,EDNRB,AASS,FOXO3,GFRA2,FREM1,GRM7,RNF165,LIX1,MATN2,MMP16,CD200,NTRK3,PDGFRA,PCDH18,NECAB2,FAT3,ROBO2,SATB1,ST8SIA1,ZNF423,SSTR2,ADGRL3,FAM124A,PAK5,ST8SIA2" Coexpression 18989386-Table2 Human StemCell_Ding08_50genes GeneSigDB 3.37E-05 3.89E-01 7.41E-04 7.37E-03 19 47 "ADGRB3,ERC2,DCT,FAM107B,WIF1,KCNA2,MYBPC1,PCDH9,PENK,PLP1,PTN,SUSD4,ROBO2,SCN2B,TNFRSF19,NTNG1,FAM155A,VLDLR,SCG2" Coexpression M4665 Genes down-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.44E-05 3.98E-01 7.57E-04 7.52E-03 99 434 "ACADM,ADD3,ADORA1,BCAR3,PPFIA4,ARHGAP5,ATP2A2,N4BP2L1,CFLAR,BMP7,DST,CACNB2,THSD7A,CANX,CAST,UBE2L6,LETMD1,PREPL,CLIP3,LRIG1,VCAN,PDE4DIP,DCAF8,PHYHIP,TOMM20,SCRN1,SPOCK2,ARMCX2,MAGI2,RABGAP1L,KBTBD11,DPP6,ABI1,RCAN1,GNE,ECM2,DYRK1A,DNM1L,FRY,OPTN,AASS,ERBB4,F3,CORO2B,ST3GAL6,FGF1,PDLIM5,NPTN,PNMA2,SARAF,FYN,GALC,IQGAP2,MTHFD2,GHR,GLUL,FERMT2,GRIK2,NR3C1,GYG1,ARHGAP19,SYNPO,HSP90AA1,ITGAV,KCND3,CD200,NTRK2,PCMT1,PDE4B,SCHIP1,PRKACB,MAPK10,KLK6,PSMA6,PTH1R,PTPRD,PTPRO,RDX,RGS10,ATXN1,PALLD,FNBP1,CAND2,DDN,NFASC,KANK1,CAMSAP2,TGFBR3,BEX4,PARD3,SSBP2,TUBB2A,HIRA,FLRT2,TOM1L2,XPO1,SEMA3B,HNRNPA3,CERS6" Coexpression M2928 Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain Y). MSigDB C7: Immunologic Signatures (v6.0) 3.57E-05 4.13E-01 7.80E-04 7.75E-03 38 128 "ACTN1,ADCY6,ADRA1B,DGKZ,SFMBT2,ZBTB10,DDX3Y,RGS9,VSTM2A,CNN3,LRIG1,GPSM1,HDAC9,CHST15,IQCG,EVL,STON1,GUCY1A1,BACH2,TUBB2B,MATN2,PDE3B,PKD1,SLC25A23,EML5,SATB1,SELL,MAGI3,ST6GAL1,ST8SIA1,DZIP1,CCDC88A,SCMH1,TCF4,TCF7,SLC44A1,TRIO,CERS6" Coexpression M18322 Genes up-regulated in RD-EF cells (rhabdomyosarcoma) engineered to express EWSR1-FLI1 fusion [GeneID=2130;2313] and which are also highly expressed in Ewing's famliy tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.59E-05 4.15E-01 7.80E-04 7.75E-03 29 88 "PPFIA3,ATP1A1,GYG2,KYAT1,CCK,ARHGEF1,CHN2,CSNK1E,DAPK1,SIRPA,DPYSL2,FCGRT,OLFM1,CSPG5,JAK1,VWA5A,MAN2A2,MAPT,NELL2,PFKP,CDK14,PRKCB,RAP1GAP,ST6GAL1,WDR47,FNBP1,SYT1,TRIM2,SLC17A7" Coexpression 15930281-Table1 Human BoneMarrow_HuLieskovan05_107genes GeneSigDB 3.59E-05 4.15E-01 7.80E-04 7.75E-03 29 88 "PPFIA3,ATP1A1,GYG2,KYAT1,CCK,ARHGEF1,CHN2,CSNK1E,DAPK1,SIRPA,DPYSL2,FCGRT,OLFM1,CSPG5,JAK1,VWA5A,MAN2A2,MAPT,NELL2,PFKP,CDK14,PRKCB,RAP1GAP,ST6GAL1,WDR47,FNBP1,SYT1,TRIM2,SLC17A7" Coexpression M6537 Genes up-regulated in epithelial cells (6h): interferon alpha versus interferon alpha and IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 3.59E-05 4.16E-01 7.80E-04 7.75E-03 53 199 "DPF1,RNF157,SEMA6A,BBOX1,GAS7,USP37,ATP6V0A1,ARHGEF1,CD81,CDC25B,CCPG1,CHRNA4,CHD1L,B3GAT3,RAB39B,RBM12,SLC37A3,ZCCHC17,DLL3,GALC,SEPT9,GART,MSL3,FERMT2,B4GALNT4,GPR37,NAT8L,MDM4,MKLN1,BCO1,NEUROD2,NINJ2,FAM216A,SMIM7,TMEM206,SYNDIG1,FAM192A,SCN4B,NTNG1,SMTN,ADHFE1,PCDHB10,AKNA,CYB561A3,TP53BP1,NR2C2,CLEC2L,PITPNB,VAV1,PLPP4,ZNF142,EMSY,CSDE1" Coexpression M6523 Genes down-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 3.59E-05 4.16E-01 7.80E-04 7.75E-03 53 199 "ACTN1,NDRG2,RNF157,MRTFA,TMEM263,AP1M1,ENTPD6,ARHGEF2,NOG,MFSD4A,C2CD2,KIAA0040,SCRN1,AK5,ARRDC4,FARSB,E2F5,ATL1,C8orf37,RASGRP2,RABEPK,SLC43A2,ZNF391,ARMCX1,FECH,NBEA,MPP6,GABBR1,HBS1L,RAPGEF6,BACH2,METTL21A,MOV10,NFE2L2,NRCAM,NUCB2,SPATA6,PRKAR1B,QDPR,GAL3ST4,PTGR2,ZFP2,CLUAP1,ZC4H2,SYPL1,TACR1,BHLHB9,METTL3,SSBP2,UBTF,TOM1L2,ZNF711,ZNF248" Coexpression M5566 Genes up-regulated in comparison of basophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.59E-05 4.16E-01 7.80E-04 7.75E-03 53 199 "ADD3,N4BP2L1,BID,OSGIN2,BSN,CALM1,ARHGEF10,SOCS5,CYBB,ZFYVE16,RASSF2,GIT2,SIRPA,PDCD6IP,EIF1,ST3GAL6,STAG2,GABRA1,GALC,WIF1,HP,JAK1,KIT,MBP,SHC3,PIK3C2A,CCSER2,LRP12,PILRA,PTPRE,PTX3,DCUN1D2,PRR5L,SUPT20H,CPEB3,R3HDM2,SLC4A3,SORCS3,CDK19,POGZ,EPB41L3,PLCB1,AGTPBP1,WASHC4,TMOD1,BEX4,TPM1,ZMYND8,TSC1,CLIP2,GDPD5,ZNF37BP,TIGD6" Coexpression M6631 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min stimulation by: LPS versus IL6 [GeneID=3469] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.59E-05 4.16E-01 7.80E-04 7.75E-03 53 199 "PLEKHG5,API5,AQP6,MYOM1,TTLL9,RAB29,CALB1,PPT2,TOGARAM2,PLCH2,DNM2,MAMLD1,ST8SIA3,ING4,EIF1,PLEKHO1,RASGRP2,SPEG,APC2,TAOK3,FGF1,ATP13A4,DACH2,FREM1,GGT5,GLUL,GNG3,MCHR1,PTPN5,ZBTB49,BVES,FRMD5,SCRT2,KCNJ3,ADAM22,SDK2,DIRAS2,ZMAT4,PAQR6,SLC1A6,SLC1A7,SON,SOX1,UHRF1BP1L,SSTR2,SLC37A2,TIE1,NR2E1,RIMBP2,TPD52L2,NAV3,SNX27,WNK3" Coexpression 15475448-Table3 Human Thryoid_Chevillard04_139genes GeneSigDB 3.64E-05 4.21E-01 7.86E-04 7.81E-03 34 110 "ADD1,APLP1,ASCL1,ATP2B2,CDK5R1,SCARB1,QKI,CNN3,CSF1,DPP6,PDCD6IP,EPHB1,SRRM1,ERCC2,FGFR1,OGA,GNAL,KCNF1,MAP4,NTRK2,NTRK3,PC,PDCD2,PLP1,POLG,PTPRE,SLC12A4,PEG10,SYT11,ABCC8,ARHGEF12,UBE3A,VSNL1,SSPN" Coexpression 17430594-table4 Human Prostate_Chandran07_154genes GeneSigDB 3.64E-05 4.21E-01 7.86E-04 7.81E-03 34 110 "PKP4,NCOA1,BMP7,CDH10,KMT2C,MAP4K4,BOC,EGR3,EFS,FGF13,FOXM1,ZNF605,ZMYND11,BRD8,EML4,LSAMP,AFDN,MN1,NBL1,NINJ2,CNTN3,PCDHGC3,PCDH18,PPP3CB,PTN,RBBP6,ROBO2,HES6,SFPQ,SOX2,SPP1,ZNF621,CLASP2,THBS4" Coexpression M5354 "Genes required for proliferation of DLD-1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.67E-05 4.24E-01 7.91E-04 7.86E-03 48 175 "NME5,TAOK1,ALK,PDXK,STK33,BTK,KALRN,ARHGEF25,ARHGEF2,PICK1,AKAP7,AKAP6,CSNK1E,APPL1,DLG2,DMPK,RPS6KL1,EPHB1,SPEG,RCSD1,TAOK3,FGFR3,FYN,DBF4,GRK4,PACSIN2,PIK3AP1,STK32C,NF1,CDK14,CAMKV,PIK3R1,PKM,EXOSC10,PPARA,PRKACB,PRKAR1B,PRKCG,MAPK8,STK32A,FIGN,STK32B,SPHKAP,TNIK,HECW1,SYT4,SYT5,TRIO" Coexpression 16611997-SuppTable1 Mouse StemCell_Affar06_525genes GeneSigDB 3.68E-05 4.25E-01 7.92E-04 7.87E-03 100 440 "ABAT,AXIN2,SLC12A5,ALCAM,APOC1,API5,LGR5,SLC4A4,MYOM1,ADAM15,PRC1,CBLN1,SCARB1,CDO1,RAB3C,CLU,FADS2,COL9A3,LRIG1,CTNND2,B3GAT3,GSDME,SPOCK3,CHRDL1,DMPK,DUSP9,ABCC5,EDNRA,EFNA3,EGFR,ELAVL3,PCOLCE2,CEND1,MRVI1,EFEMP1,FDFT1,POLK,FOXM1,FLT1,FOLH1,SMC2,ST6GALNAC3,NRG3,FYB1,DKK3,GALR1,MTHFD2,GFER,GFRA1,PSRC1,MCHR1,HAS2,HMGB1,HSD17B1,HSF2,STMN1,MATN2,IL17D,MYCN,MYH3,MYH6,MYH7,FXYD6,NAP1L3,NASP,NNAT,NPTX2,PDGFRA,PFKFB2,PLTP,PRKAR1B,MAPK10,PROX1,MASP1,ELOVL2,PTPRO,SLC1A6,SNRPN,SOX2,SPP1,BEX1,SULF2,SYT11,JMJD6,PLCB1,TAC1,HHIP,THBS4,TNFRSF1B,TPM1,TUBB2A,UBC,UCHL1,VAV1,XRCC4,ATP6V0E2,CELF4,FZD3,SOCS4,SLC4A10" Coexpression 20220088-SuppTable3 Human Immune_Allen10_81genes GeneSigDB 3.71E-05 4.29E-01 7.97E-04 7.92E-03 22 59 "MTUS1,KIAA1324,CDK5R1,CDH2,CHGB,CHI3L2,TJP2,CNIH3,HEYL,NCKAP1,GNG4,TOX2,SMAD1,CD200,NFIA,NTRK3,KSR2,ST8SIA1,PEG10,HEY1,DCBLD1,FZD3" Coexpression 16818663-Table3 Human Esophagus_Joshi06_129genes GeneSigDB 4.00E-05 4.63E-01 8.57E-04 8.51E-03 33 106 "ADCY2,BRAP,KIDINS220,APBB2,CDC14B,CADPS,RASL11B,ASTN1,ADGRB3,DST,MTMR3,CDC42,DCT,C2CD2L,TMCC2,DLG3,EPHB1,TUBB4A,AFF2,GRIN1,MBP,PPARA,BCAS3,RDX,RET,GTDC1,SLC9A5,SOX2,MPRIP,AJAP1,TMPRSS5,ZNF610,PRDM10" Coexpression 18277965-TableS1b Human Liver_Skawran08_551genes GeneSigDB 4.02E-05 4.65E-01 8.57E-04 8.51E-03 97 425 "SERPINA3,ACADM,OSBPL1A,LTBP4,ANK2,ANK3,VAT1L,ARNTL,ARRB1,GPR146,C1QC,PRMT9,CAST,CDO1,UBE2L6,RCBTB2,MS4A7,CLCN3,LY86,CP,CRHBP,AKAP12,ATRNL1,SDC3,PLCXD3,ZNF337,DCT,ZEB2,SV2B,DLG4,SLC25A18,RCAN1,GNE,EDN1,EDN3,LPAR6,RCAN2,FABP7,FCGR3A,FGFR1,FHL1,PDLIM5,B3GAT1,IP6K3,SYT17,SESN1,GHR,LYVE1,GPD1,GPM6A,NR3C1,MFSD2A,GUCY1A1,HBA1,HPS5,VSIG4,ACOT7,HP,IFI16,IGF1,KCND3,KIF5C,LIFR,MT1M,MXI1,ODF2,GPR88,PCDH9,PDE4D,PLTP,GRAMD1C,ACSM5,RET,RGS7,LRRK2,WLS,SARS,LRFN5,SCP2,TRIM46,SHMT2,SLC4A3,SLCO1A2,CXXC4,OGDHL,SPART,SAMSN1,EPB41L3,SYN1,SIN3B,TEK,TGFBR3,TIE1,TNFRSF1B,SLAIN1,ZNF24,DNALI1" Coexpression M2370 "Oligodendrocyte core differentiation genes: up-regulated in Oli-neo cells (oligodendroglial precursor) at 10 h after treatment with PD174265, dexamethasone or isotretinoin [PubChem=4709, 5743, 5282379]." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.03E-05 4.67E-01 8.57E-04 8.51E-03 17 40 "ABAT,DSCAML1,NUMB,MAP7,SLC25A27,ELMO1,SORBS1,INPP5K,IL6R,KCNA1,MBP,OPCML,PAK3,BCAS3,ANKRD6,UGT8,PAK5" Coexpression 17880687-TableS4 Human Embryo_Heim07_273genes GeneSigDB 4.08E-05 4.72E-01 8.57E-04 8.51E-03 52 195 "VAT1L,CDC14B,ASPH,CA12,JAM2,VAX2,CNR1,AKAP7,CNTNAP2,BRINP1,MEX3B,FLT1,MPP6,IQGAP2,CPLX2,GCNT2,PCDH17,TOX3,LNX1,KCNJ4,CHST6,SHC3,MEIS1,PPM1L,NFIA,NODAL,NPTX2,PBX1,PMP22,SLC22A23,PTPRZ1,RET,PRIMA1,SALL1,SCN4B,ANKRD6,LIMCH1,PDZD2,KIF21B,KLHL7,SYN2,PDLIM2,TCF7,PCDHAC2,TEK,LEFTY2,TIMP4,FLRT2,VSNL1,WNK1,NHSL1,SSPN" Coexpression M2905 Genes up-regulated in DLD1 cells (colon carcinoma) over-expressing LEF1 [Gene ID=51176]. MSigDB C6: Oncogenic Signatures (v6.0) 4.08E-05 4.72E-01 8.57E-04 8.51E-03 52 195 "BMP7,CBS,DCLK1,CHGB,COL9A3,AKAP12,CTH,DBN1,DNAJC6,EGR3,EN2,PLEKHO1,FGF13,FHL1,FOXG1,FOXF2,FLNC,DLL3,MPP6,WASF3,GJB1,PCSK1N,GNAL,GNG4,ADAMTS8,NR3C1,HAS2,ELOVL5,TUBB2B,L1CAM,LMO2,MAOB,NELL2,PAX6,PCSK5,PLTP,PRPH,PTPRN2,RYR1,SLC6A8,SLIT1,PDZD2,FNBP1,NMNAT2,ARC,OBSL1,SLC35G2,ZFPM2,HEY2,TMOD1,TNFRSF1B,PMEPA1" Coexpression M6516 Genes down-regulated in epithelial cells (6h): untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 4.08E-05 4.72E-01 8.57E-04 8.51E-03 52 195 "ACTN1,MTA3,AP2A2,AK2,CACHD1,APP,TMEM263,ARRB1,N4BP2L1,NOG,CNN3,NSL1,KIAA0040,ARHGAP32,ZFYVE16,SCRN1,AASDH,ATL1,ANKRD46,C8orf37,RASGRP2,SLC43A2,ARMCX1,NBEA,MPP6,GABBR1,RAPGEF6,PRDM5,ATG4C,MSRA,ZC3H12B,NRCAM,NUCB2,ETFRF1,TMOD2,PLCL1,SDK2,SPATA6,GAL3ST4,PGBD4,PTGR2,ZFP2,CLUAP1,SPART,ELOVL4,PJA1,TCF7L2,TRIM2,ZMYND8,SSBP2,TOM1L2,ZNF711" Coexpression M16488 The lung adenocarcinoma TSP (tumor sequencing project) genes that were found significantly mutated by at least one method. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.11E-05 4.75E-01 8.57E-04 8.51E-03 13 26 "APC,ATM,EGFR,EPHA5,ERBB4,ZMYND10,GNAS,LRP1B,NF1,NTRK3,PAK3,PDGFRA,PTPRD" Coexpression M9035 Genes up-regulated in macrophages with heterozygous knockout of HDAC3 [GeneID=8841]: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ACTN1,SORCS2,MRTFA,PITPNM2,CAMK2D,CBFA2T2,CACNA2D2,CLOCK,CRY2,IST1,IP6K1,ARMCX4,NR1D2,PLEKHA1,CALCRL,DNAJC27,CD320,KIAA1109,CAP2,TACC2,NSG2,SARAF,ZMYND11,ATP8A2,BACH2,ITPKB,KCNK2,SMAD1,AFF1,PIK3C2A,RETREG1,CDIP1,SPATA6,KLK6,PTK2,EML5,MSANTD2,RGS10,SELL,DZIP1,ZFP1,KDM3A,STAU1,PHLDB1,STX1A,ZFP90,AMACR,UBE2H,STMN4,RNF103,PPP1R3F,DPF3,RNF146" Coexpression M7875 Genes up-regulated in macrophages: LYVE1+ [GeneID=10894] versus LYVE1- [GeneID=10894]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "NCKAP5,ACTN2,SLC25A25,PLEKHG5,PNMA8B,LTBP4,RIPK1,PROM1,BMP7,SUMF2,CP,CRY2,GREB1,C2CD2L,GRIN3A,OLIG1,DNAJB6,RBM12,EGR3,PLEKHA1,DCTN4,GPHN,GTF2IRD2,FGF13,FOXG1,NKX6-2,KLF12,CAMK2N2,MDM4,PCBP3,ZNF827,CYTL1,OLA1,SNX10,SLC25A23,MTRF1L,MAPK8,PRR5L,YJEFN3,FOXRED2,ITSN1,FAM219A,THSD1,STXBP1,DNAJC9,EHBP1,LEFTY2,BHLHB9,CLDND1,ZIC1,ZNF213,WNK3,PAK5" Coexpression M6556 Genes down-regulated in monocyte-derived dendritic cells: untreated versus AM580 [PubChem=2126]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "CARNS1,APBB1,PHYHD1,STX16,BACH1,SCAPER,TJP2,PCYT1B,SH2B1,CSNK1E,PDE4DIP,ARMCX2,MTX3,PRKAG2,ZNF274,MALT1,B4GALNT4,L1CAM,TTYH2,PAXBP1,GPR155,MAN2A2,MATK,MATN2,ZNF862,ZNF827,PIK3R1,PLCL1,ANKRD16,POLG,SYTL2,PTPN13,EML5,ARID4A,BSDC1,RFX3,CCDC82,PEAR1,ANKRD6,RAB3GAP1,SLC20A2,CEP68,DIP2A,STX1A,ACSBG1,PJA1,TRIM2,TIAM1,TMOD1,TUBB2A,DNAJC12,MICU3,FRMD6" Coexpression M7432 Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: TGF beta versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ACTN1,ADAR,AXIN2,CARNS1,AMPD3,ARHGEF10,KIAA0040,PITPNC1,DNAJC6,DMTF1,RASGRP1,RASGRP2,KIAA1109,MEX3B,NSG2,ZMYND11,RAPGEF4,GSN,FICD,L1CAM,MATK,SRSF12,MSRA,P2RX7,PDE2A,SERPINI1,PTPRE,RASGRF2,ATP8B4,ZNF354C,SCP2,SCG5,FAM102A,DZIP1,RUFY2,SLC14A1,ATF7IP,TET1,KIF21B,SP4,MYCBP2,ARHGAP26,RAP1GAP2,SRPK2,SYNE2,C3orf70,TBCEL,AKNA,ARHGAP9,SGK3,ITM2C,CERS6,KLHDC1" Coexpression M8653 Genes up-regulated in P14 CD8+ T cells: ST2 [GeneID=6761] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ADD3,SNX30,TXNDC16,FGD2,PDXK,NCOA1,RASL11B,EIF4G3,DOCK11,CAMK2G,RCBTB2,SOCS6,CNOT8,ANKRD44,ABCG1,PHF14,RIPOR2,HP1BP3,DPYSL2,LPAR6,PRAM1,PRKAG2,FOXO3,ANKFY1,SESN1,GYG1,ARHGAP19,HMGCL,IL6R,DIPK1A,L1CAM,GPR155,MAN2A2,NUMA1,P2RX7,PDPK1,PPP2R5C,SLC26A11,PCMTD2,RASA3,ITSN1,ZCCHC24,KIF21B,CDK19,SRPK2,SEPT3,PDLIM2,TCF12,ARHGAP9,HEY1,SNX27,MPPE1,NHSL1" Coexpression M5620 "Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569] versus those treated with TGF3B [GeneID=7043], IL6 [GeneID=3569] and IL23A [GeneID=51561]." MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "AXIN2,GPRASP2,ZNF583,MTMR7,QKI,SLC4A7,LRIG1,GAPVD1,PITPNC1,FBXL5,MBNL2,RTN3,DUSP27,SLC9B2,ARFGAP2,ATP2C1,DLL3,SDCBP2,GABRB1,TUBA8,GFRA2,ATF7,ATE1,GSN,NCKAP1L,MAOB,MEIS2,NPTX1,ZDHHC8,PRKCB,PTCH1,PTPRZ1,RDX,RGS10,RGS12,RIC8B,AP1AR,RASA3,SCAF8,FBXO11,ARHGEF40,BTBD7,ZFP1,SCN3B,SS18,STX1A,ZEB1,WASHC4,PIK3R5,UBE2H,TBC1D15,CADM2,RSPRY1" Coexpression M9272 Genes down-regulated in spleen B lymphocytes versus bone marrow plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "RNF157,GRAMD1B,ADORA2A,ALAD,SEMA7A,EPB41L5,APP,ARHGAP5,ATP2B1,CDK5R1,BAIAP3,CDC25B,CRMP1,CSF2RA,OSBPL3,MYADM,SPOCK2,RAB39B,PLXNC1,C8orf37,ST3GAL6,GAA,GPM6B,GPR34,TOX2,KCNC2,KIF5C,CAMK2N2,GPR155,MATK,CHIC1,PDE2A,ABCB1,PLXNB1,POU6F1,PPP3CC,SLC26A11,PTPN13,PID1,RALGDS,SALL1,MAPK12,SCN8A,PEAR1,FAM214B,ARHGAP26,SYT11,GPRIN3,ERCC6L2,TRH,MICAL1,ITM2C,ST8SIA2" Coexpression M6927 Genes up-regulated in B lymphocytes: anti IgM versus CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ADD3,ADORA2A,SPOP,USP28,N4BP2L1,SYNGR3,ACBD5,IPCEF1,GALNT9,KIAA0040,PNPLA8,RIPOR2,CENPL,IP6K1,ARMCX2,FBXO25,ANKRD46,MBNL2,ASB3,ING4,SLC43A2,SH3YL1,TESK2,FOXO3,EVL,ZNF512,ZNF274,C15orf41,NEU3,SESN1,MSL3,CBX1,DIPK1A,ARHGAP12,SFR1,NEK1,TMIE,RETREG2,OXR1,ZYG11B,UEVLD,ST8SIA1,DZIP1,SLA,ZNF667,KDM4B,KIF21B,TCF7,MTMR14,UBE2H,SLAIN1,SPATA13,SENP7" Coexpression M6618 Genes up-regulated in bone marrow-derived macrophages with IL6 [GeneID=3569] knockout and 45 min of stimulation by: LPS versus IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ABHD6,PPFIA4,SPAG9,CCPG1,QKI,MAGED1,PNKD,DOCK4,MYADM,ARHGAP24,NR1D2,SIDT2,SORBS3,ETV1,KATNAL1,EZH1,FOXO3,ZBED3,USP21,GHDC,ARHGAP19,HMGCL,IL6R,PTOV1,MXI1,CNOT4,STRN3,SPATA6,FAT3,PRKAB2,MAPK3,PRPSAP2,BCAS3,RAB5B,TMLHE,FOXRED2,SEC14L1,CHD9,RAB3GAP1,SCN3B,FAM219A,FNBP1,EPB41L3,ANKRD28,CAMSAP2,SMG6,ATP13A2,MTMR14,ZKSCAN5,MICAL1,VPS35L,PLSCR4,FRMD6" Coexpression M8052 Genes down-regulated in T cells: control versus TX527 (hypocalemic analog of 25-hydroxyvitamin D3 [PubChem=1593]). MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "MTA3,ALCAM,ABCD2,MAP4K3,ST3GAL5,BSN,CACNA1D,REPS2,FOXN3,CHM,C1QL2,ABCG1,CST3,DCAF4,PLEKHM1,FAM107B,PLXNC1,EXTL2,EYA1,TAOK3,ZMYND11,GALC,INPP5K,ACSS1,SESN1,GPR34,PADI2,KTN1,VWA5A,GPR155,CDK18,DRAM2,RASGEF1B,OXR1,WLS,ATXN7,SUPT20H,CCDC88A,USP33,FAM219A,MYCBP2,ERBIN,CEP68,DNAJC9,WASHC4,TPD52,TSC1,MICAL1,WIPF1,GDPD5,TMEM178A,PAK5,FRMD6" Coexpression M7437 Genes up-regulated in CD4 [GeneID=920] T cells: TGF beta versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "BRAP,AP2A2,DGKD,LGR5,SLC4A4,N4BP2L1,HCN2,VXN,BRSK2,CCNT1,RGN,CBFA2T2,DLGAP1,MAP4K4,AIF1L,DCTN1,DNAH9,DUSP9,ST6GALNAC3,FUT9,GNAL,GPM6A,GRIN2D,ATG4C,MSL1,TTYH2,JAKMIP3,DDR2,NUMA1,PALM,POU3F4,KANSL1,SLC26A11,KHDRBS2,SCN4B,SCN7A,ZFP30,LIMS2,NAPB,LGI3,KIF13A,SOX10,SEPT3,CNTN2,FAM189A1,FBXL16,RGMB,PROCA1,DHX33,SLC17A6,ADAMTSL3,CBLN2,ST8SIA2" Coexpression M7909 Genes down-regulated in wildtype bone marrow-derived macrophages: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "KLHL13,INSYN2B,ATP2B3,KALRN,LARGE1,CLCN3,KIAA1549L,NIPBL,LRRC3B,DZIP3,CTNND2,ST18,GAPVD1,RIMS3,AIF1L,PITPNC1,PLPPR4,MBNL2,C3orf18,PAN3,TMEM74,CDKL3,FAM198B,TAOK3,GABRA4,GABRB3,CSDC2,LPAR4,GRIA2,KCNN2,HECTD2,ASPRV1,MMP16,FXYD6,NFIA,NOVA1,PDE1C,PRKACB,PTAFR,SLC1A2,URGCP,MBD5,SON,SPATA7,MYCBP2,LMO3,ASTN2,TBX15,WASHC4,ERCC6L2,PITPNB,XRCC4,PROCA1" Coexpression M9381 Genes up-regulated in follicular B cells versus marginal zone B cells. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "MAP4K3,USP28,GPAM,ATP2B2,AZGP1,OSGIN2,BTRC,DDR1,CACNA2D1,SLC5A11,MS4A7,IGLON5,AKAP7,CNRIP1,PPP6R2,USP6NL,BOC,DSCAM,NCALD,CACNG3,TMEM132C,PRAM1,FOXO3,MTHFD2,CPLX1,NEU3,GRIN2D,GRM2,FRMD5,GPR155,MAP6,MEF2C,SESN3,NCF2,DDR2,GPR88,OPA1,GDAP1L1,PRIMA1,C12orf49,SCN2A,SCN2B,CNKSR2,SLC8A2,HECW1,SSTR2,HIF3A,P2RY12,PLPPR5,SLC30A4,EMSY,SEMA3B,IFT88" Coexpression M5324 Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 72 h versus those from old donors treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "CLK4,SPOP,CAPRIN2,STX16,B3GALT2,N4BP2L1,SYNJ1,FOXN3,ZBED5,CSF1,CSF2RA,CX3CR1,MAML1,GSDME,FAM13A,SUGP2,AASS,PLEKHA1,ING4,BSCL2,ATP8A1,SARAF,FYB1,NFU1,NR3C1,HLF,RBPJ,CD200,MXI1,NELL2,CNOT4,SLC11A2,OGG1,TREM2,PDCD2,PDE3B,ZFYVE21,PRKCB,BCAS3,PTCH1,ZSCAN32,RFX5,PCMTD2,PRR5L,TRAPPC13,ATXN2,ST8SIA1,EPB41L3,SYT11,TIAM1,CAB39L,ZNF37BP,ZNF248" Coexpression M6789 Genes down-regulated in lymph node B lymphocytes: untreated versus interferon beta. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "METAP1D,KDM5D,ADAR,RNF150,ANK3,AQP4,ARHGAP5,KSR1,BSN,CDK5R2,CACNB4,CAMK2A,CLDN10,CACNA2D2,ABCG2,TENM4,SNAP91,DYNC1I1,VPS13B,TUBA1B,FCGR1A,POLR1B,AKAP3,PRELID3A,KBTBD12,B3GAT1,DKK3,GABRA5,GAD1,IQGAP2,CPLX2,DCLK2,FAM222A,KCNC2,MAP2,NEFH,ANLN,PLEC,TMEM255A,MYH14,ARMH4,TRIM46,SLC12A2,SCN3B,DOP1A,C11orf87,STOX1,STAC2,AJAP1,GSE1,SYT1,IQCE,PIK3R5" Coexpression M4571 Genes down-regulated in comparison of thymic progenitors versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ACTN1,NDRG2,ADCY6,ADRB2,TXNDC16,ALDH7A1,CBLN1,CACNA2D2,RAB33A,CTNND2,DAPK1,FBXO25,DLG3,ABCC5,ANKRD46,HEYL,SIDT2,ATP8A1,PDLIM5,FYB1,NR3C1,FICD,AGFG1,TUBB2B,KCNJ9,MBP,TM6SF1,MIA2,SETD4,CAMKV,TMEM38A,PPP3CB,PRKCB,SNRK,PTPN13,PTPRO,RASGRF1,ARHGEF10L,HUNK,SATB1,CDK5RAP2,SYNE2,SLC37A2,DNMBP,SIN3B,CUX2,SYNE1,ARHGAP9,PRRT1,CDK20,TUBB2A,PMEPA1,EVI5" Coexpression M6629 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus LPS and IL10 [GeneID=3486]. MSigDB C7: Immunologic Signatures (v6.0) 4.16E-05 4.81E-01 8.57E-04 8.51E-03 53 200 "ADRB2,KIDINS220,TBC1D14,GPAM,ATP2B1,GPR146,CAST,SOCS6,CNOT8,DOCK4,DCTN1,NR1D2,SLC12A6,ANKRD46,ING4,ETV1,GYG1,TOX2,ARHGAP12,LDLRAD3,PTOV1,CNOT4,OPA1,OPHN1,TREM2,PKD1,ZFYVE21,RETREG1,PMP22,PRKAB2,BCAS3,RNASEL,SEMA6D,ATXN1,SEC14L1,CHD9,ST6GAL1,SIRT2,BTBD7,SEPT8,DIP2A,STX1A,SULF2,ANKRD28,CAMTA1,CAMSAP2,ARHGEF12,TPD52L2,P2RY12,SPIRE1,RNF103,PLSCR4,FXR1" Coexpression M7514 Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.30E-05 4.98E-01 8.84E-04 8.78E-03 91 394 "ACADM,NDRG3,OSBPL1A,TXNDC16,SPARCL1,LTBP4,MRTFA,ANK3,CASK,ATP6V0A1,ADAM23,ST3GAL5,CACNA1G,CACNA1A,ARHGEF25,LRBA,CDO1,TPP1,CLTA,CNN3,COL4A5,MAGED1,AKAP12,CTNND1,DCAF8,DNM1,ATN1,TOM1,EBF1,RASA4,ELAVL2,MTSS1L,FGFR1,DCTN2,ERGIC3,OGA,DKK3,GAA,SESN1,GHR,GRB10,GSN,ZHX1,SYNPO,IL6ST,LAMA2,LAMP2,LSS,MATN2,MEIS1,CCDC80,PTOV1,NRBP2,NFIX,NUCB2,PDGFRA,CDK14,SERPINE2,PIK3R1,PLCD1,PLTP,PMP22,POU6F1,PPP3CA,PTPN13,PTX3,RAB5B,RALGDS,MEG3,WLS,SCP2,HES6,SEC31A,SIRT2,SLC12A2,SPTAN1,TBX15,TCF4,ZFP90,USP22,THRA,NACC2,TRIO,SSBP2,TTC3,UBE2H,AMOT,ZNF32,MEIS3,ITM2C,SSPN" Coexpression M2901 Genes down-regulated in epithelial prostate cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.40E-05 5.09E-01 9.01E-04 8.95E-03 41 143 "ADAM23,C5,CNTFR,SLC4A8,CRY2,AATK,RGS6,GPRASP1,KIAA0087,AK5,EDN1,RASGRP1,TUBB4A,CGREF1,ARPP21,NEU3,GRM2,KCNA2,KCNQ2,MAOB,NDP,NOS1,OPCML,ABCB1,POU3F2,PTH1R,PTPRH,ACSS3,BEND5,PPP1R9A,SOX10,PLCB1,COBL,SLC19A3,TRH,DNAJC12,FLRT1,SLC26A10,ZBTB16,REEP1,SLC30A4" Coexpression M2859 Genes down-regulated in epithelial lung cancer cell lines over-expressing KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.40E-05 5.09E-01 9.01E-04 8.95E-03 41 143 "PPFIA3,CCAR2,ALDH4A1,PROM1,C5,CACNG1,SYNGR3,CRY2,AATK,PLCH2,DCC,RHOBTB1,DNM1,SHANK1,DTNB,EPB41,APC2,CEND1,CORO2B,CGREF1,TBR1,CHL1,GABRB1,CPLX2,GPR17,GRIK5,HBA1,KCNN1,ZNF862,SNTG1,TRHDE,CEP41,PRODH,PTPRH,CCDC82,SNCB,SLC19A3,TF,TLR4,HEY2,LILRA4" Coexpression M7876 Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.43E-05 5.13E-01 9.06E-04 9.00E-03 36 120 "IGDCC4,ZSCAN18,JAZF1,CA8,CACNB4,CH25H,NRXN3,FAM19A5,CNTN1,DNAJC6,MYEF2,DMPK,ELAVL2,ATP8A1,TUBA8,GFRA2,GPM6B,SOX21,SYT9,CHIC1,NPTX1,NRCAM,PDZRN4,SH3KBP1,LRRN3,PKIA,TMEM255A,SOX6,RASA3,ANKRD6,SLC14A1,SORCS3,LIMCH1,PALLD,SYNE1,FLRT2" Coexpression 19351829-SuppTableC Human Lung_Daniel09_177genes GeneSigDB 4.52E-05 5.23E-01 9.23E-04 9.17E-03 45 162 "RALGAPA1,USP31,PKP4,PPP4R4,CASK,ATP2B3,BMPR1B,DDR1,KMT2C,NRXN1,NIPBL,PCYT1B,COL9A3,MAGED1,RCHY1,CST3,ARHGEF4,GPRASP1,KIF19,SRPK3,PAN3,MFSD10,FGFR3,C1QL1,GPD2,ZNF496,MUM1,L1CAM,NAT8L,MYT1,PDPK1,TRHDE,CRLS1,CLIP1,ABTB1,CEP68,WASHC4,CLASP1,PSD3,CABIN1,TRIO,SHD,NAV2,RTN4,JMJD1C" Coexpression M2745 Genes down-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes. MSigDB C6: Oncogenic Signatures (v6.0) 4.64E-05 5.37E-01 9.45E-04 9.38E-03 51 191 "NDRG2,SLC12A5,APLP1,ASGR1,NRP2,BLM,BTK,LY86,PCYT1B,CABP1,CHD1L,CRYM,FAM131B,GIT2,SV2B,MBNL2,RCAN2,EPHB1,ZNF549,FER,SYT17,RND1,GPR12,STON1,GRIN2C,SMAP1,IRF8,KCNA4,PACRG,SMAD9,NELL2,NOVA1,NRGN,PCDH9,PLCD1,SMARCD3,RIMS1,TNIK,SOX10,PLCB1,TNS2,NR2E1,DAAM2,TRO,FLRT1,WIPF1,ZIC2,LRP8,SEMA3B,FAM182B,JPH3" Coexpression M2840 Genes up-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.65E-05 5.38E-01 9.45E-04 9.38E-03 88 379 "RALGAPA1,ADCY6,PLEKHH1,KIAA1211,KIAA1324,BCAS1,API5,SHTN1,SFMBT2,ARRB1,ADGRB2,CA12,CACNA1D,HIP1R,LONRF2,LARGE1,CACNA2D2,CHN2,SLC4A8,ABCG1,KIAA0040,CTNND2,RUBCN,TCAF1,ZFYVE16,MYEF2,SEC16A,DLG3,USP3,TRAPPC9,SIDT2,TBC1D16,STRADA,EVL,POMT1,STARD10,GART,RND1,LNX1,CACFD1,ICA1,MAPT,MDM4,MYCN,MYO6,NACA,NUCB2,PBX1,KCTD15,PPP2R2C,MAPK9,SLC26A11,CYBC1,SIDT1,ELOVL2,NKAIN1,PRRT2,NBPF1,SHANK2,MTERF2,SMARCC2,KDM4B,ZSWIM8,CLSTN2,POGZ,GSE1,PRRC2C,TMEM150C,ASTN2,IQCE,TBL1X,MGRN1,KAT6B,TRPS1,RUSC1,TTC3,CADM1,NPDC1,ZNF24,ATP6V0E2,ZNF74,SH3GLB2,INTS3,DNALI1,SLC38A1,RNF103,SNX27,CERS6" Coexpression 20460542-SuppTable2 Human Colon_Dessein10_211genes GeneSigDB 4.65E-05 5.38E-01 9.45E-04 9.38E-03 72 296 "ASPHD1,ASIC1,FAM43B,ZNF608,AGT,SYT13,FAM131A,APOC1,CPNE5,CAPRIN2,CHRD,DST,REPS2,CLU,COL9A3,GAL3ST1,CP,PNKD,SEC31B,ARHGEF10,VCAN,DZIP3,MYADM,TOMM20,DBN1,TIAM2,CEP170,FBXO25,KBTBD11,SEZ6L2,EDN1,FDFT1,PPP1R1B,FGFR3,SCARA3,SORBS1,SPECC1,RAB40B,GOLGB1,GRB10,TUBB2B,ITGA7,KCNH2,MAOB,MARK1,NCF2,OPA1,PALM,PCSK5,PDE2A,PDE4A,PDGFRA,PFKFB3,KCTD15,TATDN3,SLC26A11,SOX8,GALNT10,ST6GAL1,IFT122,SSTR1,ZC4H2,COBL,ROBO3,THRA,TPM2,CCDC14,CLDND1,GDPD5,GJC2,FXR1,SENP7" Coexpression M8872 Genes up-regulated in common lymphoid progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 4.73E-05 5.47E-01 9.58E-04 9.52E-03 52 196 "ADRA1B,AK2,SPARCL1,ARNTL,NOL4,CDK5R1,SYNGR3,NDST3,NRXN2,TMEM59L,CREM,FAM131B,EEF1A2,MBNL2,PLXNC1,SORBS3,TMEM35A,FYN,GDF9,GPR17,PTPRT,GYG1,TUBB2B,MITF,NAP1L2,NKX2-2,SMOX,PLXNB3,TRHDE,PLPPR1,PTPRZ1,PYGM,KLHDC8A,EFHD1,BEX1,SPART,POGZ,SYP,MTCL1,CAMSAP2,ATMIN,EHBP1,PCDHGA10,ARHGEF12,ICAM5,VLDLR,PORCN,CLDND1,KCNK12,ZNF142,ZBTB16,AP3B2" Coexpression 19658182-Table1a Human Thyroid_Arora09_27genes GeneSigDB 4.75E-05 5.49E-01 9.60E-04 9.54E-03 12 23 "ANK2,COL9A3,ELMO1,EFEMP1,GATM,KIT,MATN2,SLIT1,SPTAN1,PSD3,TIAM1,FLRT1" Coexpression M9695 Genes up-regulated in DLBCL (diffuse large B-cell lymphoma) cell lines sensitive to stimulation of CD40 [GeneID=958] relative to the resistant ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.81E-05 5.57E-01 9.70E-04 9.64E-03 53 201 "KDM5D,DDX3Y,ALDH4A1,DST,BTK,CD86,CD38,FOXN3,CLTB,MAP4K4,CREM,NCOR2,RUBCN,TOX,PARD6A,DPYSL2,EPB41L2,TUBA1B,TUBB3,ATP8A1,NSG1,HBS1L,GNAS,TUBA1C,NR3C1,HMGB1,IRF8,KCNN3,MEF2C,MEIS2,MEST,NRGN,PCMT1,CDK14,SNX10,PPP3CC,PRPSAP2,NUDT11,SBF1,CLSTN1,INTS9,PEG10,SS18,SYPL1,TACC1,PDLIM2,TCEA1,KIAA0930,SYNE1,HSPBP1,TUBB2A,VAV1,CAB39L" Coexpression M11363 A cluster of genes specifically up-regulated in gastrointestinal stromal tumors (GIST). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.82E-05 5.57E-01 9.70E-04 9.64E-03 31 98 "PWWP2A,AMPD3,DPP10,ARRB1,SLC4A4,PROM1,SYNJ1,CD81,CHN2,ANKRD44,TENM4,DYNC1I1,DMTN,ETV1,MRVI1,NEK6,GUCY1A1,KLHL23,KIT,LMO2,MYO6,PDE1A,ABCB1,RAB3A,HSPA4L,BTBD3,SLC12A2,ZMAT3,DOK6,SLC38A1,RGS7BP" Coexpression M988 Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.89E-05 5.66E-01 9.84E-04 9.77E-03 43 153 "ARRB1,LDB2,KRIT1,SLC16A4,CLU,TPP1,COL4A5,MAGED1,SNCAIP,LRIG1,EDNRA,SIDT2,EXTL2,EYA1,ACSL4,CHST15,FCGRT,FOXF2,IQGAP2,GOLGB1,STON1,GSN,HNMT,MEIS1,NUMA1,PDGFRA,ENPP2,PTPN13,SLC6A15,ZNF532,ROBO1,PCMTD2,ITSN1,SNAP25,ZCCHC24,SPP1,TCF12,HEY1,TIMP4,TRO,SSBP2,FLRT2,SCG2" Coexpression M2424 Genes up-regulated in neonatal cardiac myocytes upon knockdown of BCL3 [GeneID=602] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.01E-05 5.80E-01 1.01E-03 1.00E-02 85 364 "ACADM,AXIN2,ADRA1D,OSBPL6,ANK1,GPAM,LDHD,CA4,CH25H,PRC1,CDO1,UBE2L6,JAM2,CNR1,CP,AKAP12,DGKG,MYEF2,ABCC9,EDIL3,EDN1,EDNRB,RASGRP1,SEMA3D,AASS,ELAVL2,CALCRL,NCALD,ABCA8,FOXM1,SDCBP2,ARPP21,ACSS1,GATM,PPARGC1A,LOXL3,LNX1,GPD1,UBE2QL1,ACOT7,HP,IGF1,IGSF1,IL6R,ZNF385B,KHK,NAT8L,MATN2,MOV10,MYH3,TCEAL5,FXYD7,NEFM,OLR1,CLDN11,PCSK5,PENK,PFKFB2,PFKFB4,PGAM2,SERPINI1,SEPT4,MASP1,VPS13C,PTN,FIGN,RORB,HUNK,RXRG,SCN4B,SYBU,LIMCH1,TNIK,SSTR2,EPB41L3,TF,TGFBR3,BEX4,TNNT1,RASD2,SGK3,VLDLR,ZNF23,TMEM178A,SLC4A10" Coexpression M904 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.07E-05 5.87E-01 1.02E-03 1.01E-02 60 236 "SEMA6A,OGT,PKP4,TNRC6C,BCL7A,FUBP1,C5,CBFA2T2,ZBED5,AHCTF1,CHD1L,RBM39,NCOR1,SNCAIP,EARS2,TOMM20,MED12,E2F5,E2F6,EEF1D,ABI2,EPB41,SCARA3,USP21,ATP2C1,ACSS1,GCNT2,MAP7D2,GNAS,EML4,ZNF496,CLASRP,ARHGAP19,AGBL5,LIFR,MAN2A2,MAT2A,MDM4,MGAT3,MYCN,NAP1L1,NASP,NFYA,CLDN11,PBX1,PPM1B,PTCH1,ROBO1,EMID1,SFPQ,TRA2B,SEPHS1,IFT122,POGZ,GPR161,TMPO,SYNPO2,XPO1,ATP6V0E2,MVB12B" Coexpression M8697 Top 20 genes whose up-regulation correlated with gastrointestinal stromal tumors (GIST) and synovial sarcoma compared to other tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.23E-05 6.05E-01 1.05E-03 1.04E-02 11 20 "DPP10,APLP1,BCHE,COL4A5,TOX,EDN3,ADGRA3,KIT,PLCB2,BEX1,ITM2C" Coexpression M14698 "Genes up-regulated in the common lymphoid progenitor (CLP, defined as CD34+CD38-CD7+ [GeneID=947;952;924]) compared to a multipotent cord blood cell (defined as CD34+CD38+CD7-)." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.26E-05 6.08E-01 1.05E-03 1.04E-02 30 94 "BTK,LRRFIP1,RBM39,NCOR2,OSBPL3,KIAA0087,KMT5B,EVL,ADAM28,IRF8,MSL1,MN1,NACA,NF1,PRKCB,RBBP6,SETD5,BAALC,RPS6KA2,STK32B,SATB1,SCN3A,SLC2A5,SMARCA4,PALLD,KDM3A,COBL,TCF4,METTL3,SLC38A1" Coexpression 15308545-Table4 Human Lung_Takahashi05_17genes GeneSigDB 5.36E-05 6.20E-01 1.07E-03 1.06E-02 10 17 "APLP1,CHGA,CP,SV2A,INSM1,PTPRN,SCG5,SLC8A2,SNAP25,SCG2" Coexpression M9150 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.37E-05 6.21E-01 1.07E-03 1.06E-02 77 323 "ALK,APC,GAS7,ATM,BLM,JAZF1,CARS,RUNX1T1,USP6,CHN1,CLTC,PDE4DIP,ABI1,EGFR,OLIG2,GPHN,ERBB2,ERCC2,ETV1,FGFR1,FGFR3,FOXO3,SPECC1,SEPT9,MALT1,GNAS,CNTRL,PSIP1,HLF,TLX1,HSP90AA1,JAK2,KIT,KTN1,LIFR,LMO1,LMO2,AFF1,AFDN,MN1,MYCN,NACA,NF1,NTRK3,NUMA1,PBX1,PDGFRA,PMS2,PRRX1,RAP1GDS1,RET,FBXW7,ZNF331,SFPQ,TET1,FNBP1,ERC1,ARHGAP26,SS18,TAL1,TCEA1,ACSL6,TCF12,NSD1,ARHGEF12,KAT6B,TPM3,TPM4,ZNF384,TSC1,TSC2,NSD2,WRN,ZBTB16,FIP1L1,GOPC,NUP214" Coexpression M2736 Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of EED [Gene ID=8726] gene. MSigDB C6: Oncogenic Signatures (v6.0) 5.38E-05 6.22E-01 1.07E-03 1.06E-02 51 192 "ADRA1B,ADGRF5,BACH1,MPDZ,PTBP2,CCK,CLGN,NMT2,C2CD2,HINFP,AATK,HDAC9,ARHGAP24,RABGAP1L,DMD,ANKRD46,KMT5B,RASL12,CORO2B,PCSK1N,RAB40B,GPR37,PTPRT,NXPH3,IRF8,IL12A,KCNQ2,ENPP2,CCSER2,PDZRN4,KLK6,SLC6A15,REV3L,RGR,CLIP1,SEMA6D,SATB1,ATXN1,SLC30A10,SCG5,BTBD3,ZHX3,KIF1B,MAPK8IP3,TRPS1,DNAJC12,ZNF177,PMEPA1,EVI5,SCG2,PLSCR4" Coexpression M7266 Genes down-regulated in double positive thymocytes: TCF3 [GeneID=6929] knockout versus TCF12 [GeneID=6938] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.38E-05 6.22E-01 1.07E-03 1.06E-02 51 192 "APBB1,LGR5,CADPS,CHRD,B3GALT2,CADM3,ADGRB3,CACNA1E,ARHGEF1,DLGAP2,VAX2,SUSD5,CHD5,KIAA0087,DYNC1I1,CNNM1,DMTN,F5,FOLR2,RAPGEF6,GFAP,DCLK2,GPR22,GRIK1,FICD,MUM1,HRH3,HTR5A,NAP1L3,NPY,NOVA1,NRCAM,DDR2,OPHN1,PDE1C,PMP22,PCDHB17P,ATG16L1,RASGRF1,SLC6A15,RGS4,SNRPN,MCF2L2,DDN,TAC3,WSCD1,PCDHGB6,PCDHGA10,AMACR,MKRN3,KAT6A" Coexpression M3133 Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 5.47E-05 6.33E-01 1.08E-03 1.08E-02 52 197 "CPNE2,KDM5D,TMCC3,MTA3,AP2A2,AP1B1,WDR35,BCHE,USP6,REPS2,RAB33A,NRXN2,CREM,HP1BP3,LYPD1,GSDME,MED12,SLC12A6,ARMCX1,SH3YL1,TESK2,POMT1,ERGIC3,ZNF274,GPR34,ATP2B1-AS1,MGC16275,CELF5,LMO2,VWA5A,MATK,MBP,PTOV1,SFR1,NFE2L2,NME4,TREM2,PDE4A,RPS6KA2,SMARCE1,IFT122,LMBRD1,SPATA7,ADHFE1,VPS13A,ARHGAP9,TNS1,ZMYND8,ZNF24,SPIRE1,NUP214,ZNF248" Coexpression M2603 "Top 40 genes from cluster 13 of acute myeloid leukemia (AML) expression profile; 91% of the samples are FAB M2 subtype, all bear the t(8;21) translocation producing the AML1-ETO fusion [GeneID=861;862]; indicate good survival." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.53E-05 6.39E-01 1.09E-03 1.08E-02 14 30 "MYRF,BAIAP3,THSD7A,RUNX1T1,CACNA2D2,NCALD,NBL1,ROBO1,STK32B,KDM4B,PSD3,TRH,VLDLR,LAT2" Coexpression M15762 Neuroblastoma markers down-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [GeneID=2130;2313] fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.53E-05 6.39E-01 1.09E-03 1.08E-02 14 30 "INA,CHGA,CHGB,CRMP1,ELAVL3,APC2,GAP43,KIF5C,MYCN,ENPP2,PRPH,TMOD1,RIMBP2,SCG2" Coexpression 16210406-table1 Human StemCell_Jaatinen06_86genes GeneSigDB 5.60E-05 6.48E-01 1.10E-03 1.10E-02 26 77 "OSBPL1A,ALCAM,DST,MAP7,MAGI1,SOCS6,SLC25A27,SMARCAL1,CRHBP,RHOBTB1,SV2A,GCNT2,ADAM28,ADGRA3,HLF,ICA1,LMO2,SYTL4,PDE1A,CYTL1,PTPRD,RAD52,TCF7L2,CBX5,TRO,NSD2" Coexpression M14601 Genes up-regulated in hepatoblastoma samples compared to normal liver tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.62E-05 6.50E-01 1.11E-03 1.10E-02 54 207 "ACLY,ALCAM,LGR5,PDXK,MAP4K4,MAGED1,CS,SOCS5,DZIP3,GREB1,TOMM20,RHOBTB1,RBM12,PLXNC1,ETV1,RPS6KC1,FDFT1,SUCO,CAP2,GLUL,CBX1,HMGCR,MTR,NAP1L1,PDCD2,SERPINE2,RC3H2,RELN,PLPPR1,ACSS3,SLC25A36,ROBO1,MEG3,SEPHS1,SMARCA4,RCOR3,PALLD,RBM34,PEG10,BEX1,SEPT8,CEP68,TACC1,DDHD2,CAMSAP2,OBSL1,CBX5,R3HDM1,TSN,ZBTB38,ZNF189,MFF,MARCH8,FXR1" Coexpression 18794102-TableS1 Human Breast_Yang08_840genes GeneSigDB 5.63E-05 6.51E-01 1.11E-03 1.10E-02 80 339 "ADRB2,C1QTNF3,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2B1,SGCE,C5,DDR1,MAP7,PRC1,REPS2,SLIT2,COL4A5,COL9A3,SLC4A8,CSF1R,FEZ1,DBN1,DMD,DOCK2,DNAJB6,ABCC5,EGFR,EPS8,ERBB2,ABCA8,ATP8A1,FGFR1,FGFR3,BAIAP2,ATP5PD,EVL,SORBS1,ATP6V1H,ATP2C1,GLRB,GRB10,IGF1,JAK2,KIT,LAMA2,MAP4,MAPT,MATN3,SHC3,MID1,MSR1,MYH3,MYO5A,MYO6,NUMA1,OPHN1,PDGFRA,PDPK1,FXYD1,CEP41,PTN,PTPRB,PTPRE,PTPRN2,PTPRZ1,ROBO1,RYR1,SELL,SLC4A3,SLC20A2,SPP1,ABCC8,DNAJC9,TEK,TGFBR3,THBS4,TRIO,TST,DNALI1,SEMA3B,RTN4,SSPN" Coexpression M7725 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 5.69E-05 6.58E-01 1.12E-03 1.11E-02 47 173 "FMNL2,RNF157,SEMA7A,DGKD,TMEM184B,CNN3,PPP1R16B,DNAJC6,C2CD2L,ATL1,RASGRP1,MBNL2,PAN3,SEMA4D,TACC2,DOT1L,AHDC1,DCLK2,MAP4K5,AGBL5,TUBB2B,ITPKB,LIG4,MATN2,MBNL1,XRRA1,MMP17,NTRK3,PDPK1,PFKFB3,CAMKV,RALGDS,RGS10,FAM161B,SCN4B,MAGI3,SLA,SMOC1,MPRIP,VAMP1,ADAMTS17,SLC37A2,ZEB1,PSD3,PRRT1,PIK3R5,PARP11" Coexpression 16140871-Table1 Human Leukemia_Toren05_133genes GeneSigDB 5.98E-05 6.92E-01 1.17E-03 1.16E-02 31 99 "PROM1,CACNB2,MAP7,CLGN,B4GALT6,ARHGAP22,CRHBP,SV2A,EXTL2,FHL1,ADAM28,GUCY1A1,HLF,KIT,MEIS1,MEST,MYCN,NAP1L3,NPTX2,SERPINE2,SCHIP1,NUDT11,BAALC,ANKRD6,BTBD3,PDZD2,THSD1,SSBP2,NPDC1,ITM2C,PLSCR4" Coexpression M5767 Genes down-regulated in comparison of untreated macrophages versus those treated with IL1 and IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 6.32E-05 7.31E-01 1.23E-03 1.22E-02 52 198 "DGKZ,ADGRB1,CACNA1I,CDK5R2,ENTPD2,NEURL1,ZFYVE9,SNCAIP,SLITRK5,CCDC144A,MAGI2,CNNM1,EFNB3,ING4,DMTN,REEP2,FOXM1,SORBS1,GCK,SRCAP,USP19,LYVE1,ADAMTS13,PACSIN2,KCNH1,MAPT,NAP1L3,NHLH1,NOVA1,PFKFB2,NLE1,PRKCG,SLC6A15,STK32B,KCNIP2,ITSN1,SLITRK3,SYBU,SLC6A11,SLC12A2,SCMH1,SORCS3,IGSF9B,ARHGAP26,PCDHB3,PRMT8,TRO,UGT8,WNK1,MAP3K12,PRDM10,FAM182B" Coexpression M8379 Genes down-regulated in CD4 [GeneID=920] T cells: progesterone [PubChem=5994] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]. MSigDB C7: Immunologic Signatures (v6.0) 6.32E-05 7.31E-01 1.23E-03 1.22E-02 52 198 "ABAT,ABCD2,PLA2G4C,MPDZ,USP2,SLC16A4,CRLF1,B4GALT6,CLTC,LY86,CP,NSL1,CLIP3,ATRNL1,PPP1R16B,KIAA0040,GREB1,FRMPD4,RHOBTB1,DMD,EIF1,NCALD,F5,DLC1,DPYSL4,ATP6V1H,CGREF1,STAU2,GCNT2,GK,CNTRL,GRB10,PTGDR2,HSP90AA1,ITGAM,KCNA6,MATK,PCDH8,TCP11L1,SELL,FNDC3A,ST6GAL1,SLC1A3,ARHGEF12,TIAM1,TP53BP2,AMOT,FLRT1,DNALI1,EVI5,CIAPIN1,SLC17A7" Coexpression M5313 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 16 h versus those from old donors treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 6.32E-05 7.31E-01 1.23E-03 1.22E-02 52 198 "SLC12A5,AMPH,ANK1,MAP4K3,CDK10,PTCH2,ATP1A2,NOL4,FGF17,DST,PPT2,FAM149A,BRINP1,PLPPR4,EXOG,DMD,ABCA8,FDFT1,CAMSAP1,PDLIM5,PRELID3A,TUBA8,MSTN,GFRA1,GNAO1,GSTT2,KCNQ3,FXYD7,PDE1A,PENK,POLG,PPP2R2B,ZDHHC14,CCDC102B,MCMBP,SLC30A10,TRIM46,PUF60,SMTN,MYO16,TEX2,ATP10B,ELOVL4,ANKRD28,DNMBP,PCDHB6,CDK20,ELP5,BCL2L13,ZIC3,ADAMTS9,SNX27" Coexpression M1240 Genes down-regulated in early vs late brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.37E-05 7.37E-01 1.24E-03 1.23E-02 18 45 "NDRG2,SPARCL1,ATP2A2,CALM1,CAMK2G,CHN1,CLU,CST3,CALY,CSDC2,GNAS,ACOT7,PLP1,QDPR,PLEKHB2,CLSTN1,NCDN,ACSBG1" Coexpression M9090 Genes up-regulated in CD4 T conv: control versus over-expression of LEF1 [GeneID=51176]. MSigDB C7: Immunologic Signatures (v6.0) 6.45E-05 7.46E-01 1.25E-03 1.24E-02 46 169 "FMNL2,PI16,APOC2,N4BP2L1,DOCK11,BARD1,CACNB4,CD81,EVI5L,MAGED1,CST3,ZEB2,PLEKHM1,CD99L2,CPEB2,RCSD1,MALT1,KCNJ16,KHK,VWA5A,MATK,CD200,RTL5,NCF2,PLCB2,PLCL1,SLC25A23,PPP3CC,PXK,ROGDI,RNASEL,TCP11L1,EMID1,SEC14L1,PPP1R9A,MYO18A,ATF7IP,FAM168A,SYNE2,PDLIM2,IQCE,ARHGAP9,TMPO,NPL,RPRM,DOCK8" Coexpression M25 Genes up-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.66E-05 7.70E-01 1.29E-03 1.28E-02 19 49 "PPFIA4,APC,CCKBR,DLGAP1,GREB1,DGCR5,MTHFD2,PTPRT,MN1,ADAM22,PENK,PTH1R,REV3L,ANKRD6,DOP1A,ZNF423,AHCYL2,TPM2,TSC1" Coexpression 19286929-SuppTable2p Mouse Lung_Rangasamy09_55genes GeneSigDB 6.66E-05 7.70E-01 1.29E-03 1.28E-02 19 49 "ADD1,AMPH,KRIT1,INA,CFL2,CLIP3,DMD,ABI2,GPHN,PTK2B,GABARAPL2,SCIN,MYO6,MYO9A,TMOD2,PPP1R9A,ABLIM3,ACTR6,FMN2" Coexpression 17414055-Table3 Human pancreas_Kim07_59genes GeneSigDB 6.79E-05 7.86E-01 1.30E-03 1.29E-02 20 53 "SHTN1,CRLF1,JAM2,SLIT2,AKAP12,BOC,RCAN2,ABCA8,FHL1,GHR,IL6ST,HCN1,NLGN3,SEPT4,EFHD1,PCDHB7,TNS2,ZNF610,LGI4,MICU3" Coexpression 15459177-Table1 Mouse Brain_Kopra04_84genes GeneSigDB 6.79E-05 7.86E-01 1.30E-03 1.29E-02 21 57 "ADORA2A,KCNAB2,CAMK2D,CRLF1,CRYM,SEC24B,IQGAP2,GFAP,CBX1,MAG,MOBP,MYH7,NNAT,PENK,PGAM2,ANLN,PLP1,RASGRF1,ZYG11B,SGK1,TAC1" Coexpression M3576 Genes down-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.79E-05 7.86E-01 1.30E-03 1.29E-02 21 57 "PDXK,HAP1,LDB2,CPNE6,AASS,ASB3,EPB41,DKK3,IQGAP2,SPIN1,HES5,KCNA4,NNAT,PDYN,PENK,POU3F4,PTCH1,CCDC88A,SOX11,ATP11A,CADM1" Coexpression 20058202-Table4 Human StemCells_Secco09_28genes GeneSigDB 6.80E-05 7.87E-01 1.30E-03 1.29E-02 13 27 "BCHE,NRP2,RIMS2,FLT1,SORBS1,ST6GALNAC3,IQGAP2,PID1,RASGRF2,LIMCH1,TPD52,SYNPO2,HRASLS" Coexpression M8889 Genes down-regulated in multipotent progenitors (MPP) versus lymphoid primed MPP cells. MSigDB C7: Immunologic Signatures (v6.0) 6.80E-05 7.87E-01 1.30E-03 1.29E-02 48 179 "ADCY8,ALCAM,FAM135A,DST,HIP1R,DGKI,TJP2,CREM,AKAP12,PPP1R16B,CENPL,DNAJC6,FAM107B,DNAJB6,STX2,DENND4A,ST6GALNAC3,MALT1,NR3C1,TOX2,PADI2,ACOT7,ICA1,IDH3A,ITGAV,KCNA4,KIF5C,MYO6,PCSK1,PRKAB2,GRAMD1C,LRRC49,SYTL2,PTPN13,SEMA6D,SCP2,SLA,MAPKBP1,ENKUR,TEX2,RAP1GAP2,SAMSN1,NXT2,SEPT8,TTBK2,DNAJC12,EVI5,PLSCR4" Coexpression M14573 "Set 'NOS targets': genes upregulated and identified by ChIP on chip as targets of the transcription factors NANOG , OCT4, and Sox2 [GeneID=79923;5460;6657] (NOS) in human embryonic stem cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.80E-05 7.87E-01 1.30E-03 1.29E-02 48 179 "ADD3,CDC7,PARG,CDC14B,BMP7,CA4,CACNA2D1,SPAG9,LARGE1,FEZ1,TMEM170A,ZEB2,MED12,DPYSL2,DTNA,AASDH,KLHL5,PIPOX,FGFR1,UFM1,OGA,TNRC6A,LINGO1,HAS2,IFI16,KCNN2,ENPP2,CDK14,RASGRF2,RIC8B,SALL1,NAXD,SNRPN,SOX2,KDM3A,LHPP,KANK1,TAL1,FBXW11,OBSL1,LEFTY2,SLC44A1,ZIC1,ZIC2,ZIC3,SMARCAD1,URM1,KAT6A" Coexpression 15793299-TableC Mouse Breast_Astolfi05_1104genes_TumorGenes GeneSigDB 6.82E-05 7.88E-01 1.30E-03 1.29E-02 177 872 "NDRG2,FZD9,AK2,C1QTNF1,C1QTNF3,ALAD,SPARCL1,SRPX,ABCD2,LTBP4,ANK1,ANK3,KCNAB2,GPAM,APP,AQP4,ATP1A1,ATP1A2,B3GALT2,MYOM1,MPDZ,BID,PROM1,ST3GAL5,SGCE,DDR1,CACNG1,PRC1,ARHGEF1,CD81,CDH2,CDO1,CFL2,CHRM1,B4GALT6,CLU,ABCG2,COL4A5,COL9A1,COL9A3,CP,AKAP12,CS,FEZ2,PDE4DIP,CST3,CTNND1,RASSF2,DBT,HEPH,DNM1,GNE,DTNB,ABCC9,EBF1,EEF1A2,SH3GLB1,RASA4,AASS,EIF4G1,BSCL2,ELN,ETV1,F3,SH3YL1,ACSL4,ST3GAL6,FGFR1,FHL1,SORBS1,CHL1,GAD1,NEK6,STARD10,MSTN,GHR,GJB1,GLDC,GLUL,GPD1,GPD2,GSN,COQ10A,GUCY1B1,SCRG1,HMGCL,HP,IRF8,IGF1,IL6ST,ITGAV,KCNK1,KCNK2,KCNK3,KIFC3,LAMA2,LIFR,LMO2,MBP,MEF2C,MEST,MMP16,CD200,CCDC80,NRBP2,MYO7A,NNAT,NRDC,NUCB2,OGDH,PDGFRA,ENPP2,CDK14,PGAM2,SERPINE2,ANLN,RETREG1,FXYD1,PMP22,SEPT4,PPP1R1A,PPP3CC,PKIA,SNRK,UHRF1BP1,PTH1R,PXK,PTPRD,PTPRE,PYGM,RGS10,FBXW7,EMID1,MEG3,RTN1,RYR1,MAPK12,SATB1,SCN7A,SCP2,SEC14L1,TRIM46,GALNT10,RASA3,SGK1,SCG5,SH3BGR,ST6GAL1,SMTN,SLC15A2,LIMCH1,SOX10,SPP1,KIF1B,DDHD2,WWC1,TBX15,TCF7,ZEB1,DOCK9,TNS2,TEK,TIE1,HEY1,TNNT1,TPD52,TPM2,TMEFF2,CADM1,WIPF1,NDRG4,ZBTB16,WNK1,CSDE1,SEMA3B,PHTF2,SSPN" Coexpression M12570 Genes down-regulated in T-PLL cells (T-cell prolymphocytic leukemia) bearing the inv(14)/t(14:14) chromosomal aberration. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.82E-05 7.88E-01 1.30E-03 1.29E-02 76 320 "BRAP,ADRB2,MTUS1,ALCAM,ARNTL,NCOA1,ATM,MTMR9,CFLAR,FUBP1,CALM1,HIP1R,CDC42,CACNA2D2,ADGRG1,RCBTB2,CHN1,ZBED5,TCEAL2,CREM,ENTPD4,ARHGEF10,PPP1R16B,TCAF1,GIT2,RABGAP1L,OPTN,LPAR6,FHL1,USP16,OGA,FYN,HBS1L,MALT1,EML4,HSF2,LINC00667,MBP,NAP1L2,NAP1L3,PDE4B,PFKP,ABCB1,PIK3R1,CCSER2,PPP3CC,PRKCB,SYTL2,SNRK,TUG1,USP47,ATG16L1,RDX,ATXN1,GALNT10,ST8SIA1,WDR37,SNRPN,TNIK,KIF21B,ZBTB43,RAP1GAP2,TAB2,SYT11,ANKRD12,FAM208A,SYNE1,TGFBR3,TIAM1,TNFRSF1B,TRPC1,MICAL1,ZBTB38,TFIP11,RTN4,ZNF37BP" Coexpression M9238 Genes up-regulated in pancreatic CD8 T cells from mice with: type 1 diabetes mellitus versus healthy controls. MSigDB C7: Immunologic Signatures (v6.0) 7.19E-05 8.32E-01 1.37E-03 1.36E-02 51 194 "AMPD3,ZBTB10,DOCK11,CDK5R1,FMNL3,CLCN4,ANKRD44,SIPA1L1,DZIP3,CTNND1,PUM1,CYBB,DOCK2,DTNB,ABCC5,SEMA3D,KMT5B,RASGRP2,EVL,FLT1,ATP6V1H,CELF1,OGA,CHL1,ADAM28,AP4S1,PSIP1,BACH2,ZNF678,ZFYVE27,CHIC1,SESN3,NUMA1,SNX10,VPS13C,SNRK,RIPOR1,TTC13,ZNF844,KHDRBS2,FBXO11,ST3GAL3,SLA,SP4,ZSCAN29,PUM2,LAT2,ZNF28,SLC30A4,SNX27,SENP7" Coexpression M10664 Genes up-regulated in MFCF-7 cells (breast cancer) upon stable autocrine expression of HG1 [GeneID=2688]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.22E-05 8.35E-01 1.37E-03 1.36E-02 65 264 "HECW2,KIAA1324,SPARCL1,ALCAM,CNTNAP1,LGR5,NRP2,BMP7,SGCE,PRC1,ENTPD2,LRRFIP1,CDH18,CFL2,CPNE6,RIMS2,ZEB2,DOCK2,RCAN1,PHC2,ANKRD46,YAF2,LINC-PINT,MRVI1,FAM198B,ST6GALNAC3,GABRA4,DBF4,CBX1,GNG3,GPR12,NUDT21,STMN2,GRIA1,SOX21,MUM1,SCRG1,INSM1,SFXN5,SCAMP5,MIR4697HG,NOS1,HCN1,OPHN1,ZNF827,SH3KBP1,HYDIN,RNF220,ALG9,SARS,SATB1,CSRNP3,RIMS1,SNCA,SPATA7,PEG10,ARHGAP26,NECAB1,TK2,PRRT1,TRH,TRPM2,TSC1,UGT8,TOM1L2" Coexpression M5401 Genes up-regulated in comparison of eosinophils versus macrophages. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "ADD3,CDK13,CDK5R1,MTMR3,PTBP2,REPS2,DLGAP1,RUBCN,DBT,FBXL5,KBTBD11,HEYL,EIF1,OLIG2,ANKMY1,HPCAL4,CAMKK2,GAB1,GAD1,GLRB,GRIA2,PRDM5,WIF1,JAK1,KIF5A,KIT,MYT1,ZSCAN32,RERGL,YY1AP1,SEC14L1,FBXO11,SLA,PKNOX2,ARHGEF40,SLN,KIF21B,POGZ,ACSBG1,MLC1,SYNE2,TACC1,PDLIM2,SYNE1,TMEM151B,ZNF34,SLC44A1,MTMR14,TNFRSF1B,METTL3,TUB,ZNF184" Coexpression M4828 Genes down-regulated in comparison of CD4 [GeneID=920] T cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "ADORA3,GPR158,GAS7,SEMA4G,ARRB1,CHRD,RNF182,CA12,DIRAS1,PRC1,AKAP7,NECTIN3,TRIM69,VCAN,RIMS4,FAM169A,UBXN2A,PHYHIP,DNAL1,MYEF2,DNM1,ARRDC4,ERBB4,USP21,NRG3,GALNT15,MAP4K5,NXPH3,AGBL5,IGFBPL1,TLX1,KCNB1,KCND2,OGDH,PAX6,TMOD2,ASPDH,STRN3,ARMH4,LRRK2,PLPPR3,KIF27,HSPA4L,LGI3,WDR7,ARHGEF12,TNS2,SGK3,VSNL1,ZNF711,ZNF184,NAV3" Coexpression M9928 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 1h. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "UNC79,TRMT9B,RASL11B,ATP1A2,MYOM1,CA4,KRIT1,SLC16A4,CDH2,CHM,CHRM4,PCYT1B,SUMF2,ACBD5,CNTNAP2,DOCK4,TOMM20,YTHDC1,FBXL5,ABI1,SEZ6L2,WDPCP,EEF1A2,HIPK3,MRO,EIF4G2,EIF1,RASL12,CD320,FOXF2,SORBS1,CGREF1,GABRA2,RAB30,GPR75,GPR19,DIDO1,RABL2A,ADAMTS6,ICA1,MMP17,NAP1L2,SNTG1,PTX3,CNKSR2,SLC6A1,CEP68,CD27-AS1,PCDHB15,RFTN2,VSNL1,POLR3H" Coexpression M4643 Genes down-regulated in comparison of fetal regulatory T cell (Treg) versus adult regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "LCORL,PKP4,CACNA1I,KALRN,CAPN3,SPAG9,ABCG1,RIPOR2,NR1D2,AASS,ENO2,MTSS1L,CEP85L,SEMA4D,C2orf88,SARAF,OGA,ZNF782,EML4,COQ10A,LINC01550,KLF12,IL6R,KIF5A,KIF5C,ARHGAP12,LINC00672,NAP1L2,NFIA,OPHN1,DPY19L2P2,PIK3C2A,POU6F1,TATDN3,PTCH1,ATG16L1,RADX,MORC4,ZNF532,TRAPPC13,KIF21A,SPTAN1,ATMIN,ARHGEF12,SIRT1,PRRT1,RUNDC3B,NTSR2,DCBLD1,BCL2L13,ANKS1B,KAT6A" Coexpression M3243 Genes up-regulated in comparison of naive B cells versus plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "ABR,AP1B1,BIN1,DGKD,APP,ZSCAN18,ARHGEF7,PTBP2,CAST,ZMYM4,NPIPA1,LY86,ARHGEF6,PPP1R16B,GPRASP1,RASSF2,GIT2,ARMCX2,EVL,FYN,TRAF3IP2,ADAM28,GPM6A,EML4,CNTRL,BACH2,HSF2,LINC00667,IL11RA,INPP5B,TM6SF1,CD200,NEUROD1,SSH1,PIK3CD,SIDT1,GON4L,TUG1,RNF220,PRR5L,FAM192A,GALNT10,KIF16B,KIF21B,ZMAT3,AKTIP,TP53BP2,SSBP2,LAT2,ZFP37,ATP6V0E2,MPPE1" Coexpression M8874 Genes down-regulated in common lymphoid progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "CDC42BPA,EP400,CCAR2,BCHE,CA12,KALRN,CDH18,COL9A2,CEP170,DPYSL2,TPK1,TPPP3,GNAL,GUCY1B1,PADI2,BACH2,L1CAM,MBP,SHC3,MEIS2,MOBP,NBL1,PDE1B,SDK2,PPP1R1A,LRRN3,RAVER2,STK32B,SLC2A5,LIMS2,RAB3GAP1,RIMS1,MYO16,EPB41L3,CEP68,PHLDB1,AGTPBP1,TCF7,ZEB1,PCDHGA9,DOCK9,TIE1,TP53BP2,SSBP2,FAM155A,PITPNB,CLIP2,ZIC3,DNALI1,HPS4,UBE3B,FXR1" Coexpression M8351 Genes up-regulated in atherosclerosis macrophages: anti miR-33 versus untreated. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "NR0B1,MRTFA,ATP1A3,BCHE,CD81,MYOM2,CHGB,COL9A3,CSF3R,SUSD5,KIAA0087,ARMCX4,DRD1,TOM1,RABEPK,EXTL1,FCGR1A,FGFR1,FLT1,KHDRBS3,INPP5K,GCNT2,GNG4,GPR37,GRK4,GRM7,INPP5B,ITPKB,KHK,KIT,KLC1,LIFR,LMO2,MEST,PAH,PHKG1,RELN,RGS10,SBF1,CLSTN1,SLC15A2,APOM,GSE1,DNAJC9,TCF4,SIK3,CBX5,TNFRSF1B,TSC1,UBE2H,UBE3A,ZNF189" Coexpression M9547 Genes up-regulated dendritic cells: Ly6G+ versus Ly6G-. MSigDB C7: Immunologic Signatures (v6.0) 7.28E-05 8.42E-01 1.37E-03 1.36E-02 52 199 "KDM5D,AMT,CDC42BPA,CASK,NCOA1,SLC2A11,ATP6V0A1,NPIPA1,NDST3,SEC31B,CLOCK,ENTPD4,ABCG1,OSBPL3,ZNF337,SGSM2,G3BP2,NR1D2,ANKRD46,SIDT2,GMPR2,EZH1,AMZ2,TRMO,RAPGEF6,ZNF276,GPR75,GRB10,KIF3A,GUCY1A1,PACSIN2,ITGAM,MAN2A2,MXI1,LYRM9,PBX1,CDIP1,TNPO2,BSDC1,RNASEL,SATB1,RAB3GAP1,TNIK,CLUAP1,TSPYL2,ZNF302,SEMA4A,TIAM1,TP53BP1,PCBP4,KAT6A,CERS6" Coexpression M1466 Genes up-regulated in MEF cells (embryonic fibroblast) expressing ~25% of YY1 [GeneID=7528]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.46E-05 8.63E-01 1.40E-03 1.39E-02 55 214 "ABAT,SLC12A5,ALCAM,MYOM1,ADAM15,CBLN1,CDO1,CLU,ZNF385A,CTNND2,SPOCK3,DMPK,ABCC5,EFNA3,EGFR,CEND1,MRVI1,EFEMP1,POLK,FLT1,ST6GALNAC3,NRG3,MPP6,FYB1,GFER,PSRC1,HSD17B1,HSF2,MAP6,IL17D,MYCN,MYH3,MYH6,MYH7,FXYD6,NAP1L3,NNAT,NPTX2,PFKFB2,PLTP,PRKAR1B,MAPK10,PROX1,ELOVL2,SLC1A6,SOX2,BEX1,SULF2,SYT11,HHIP,TPM1,UBC,UCHL1,ATP6V0E2,CELF4" Coexpression M2168 Cluster 3 of aberrantly hypermethylated genes in blasts from AML (acute myeloid leukemia) patients. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.53E-05 8.71E-01 1.41E-03 1.40E-02 46 170 "SPOP,TMEM263,PCDHGB4,ZNF582,BCL7A,NRP2,MAP7,ZNF501,KCNAB3,ZFP28,CRHBP,PYGO1,MATR3,ELAVL2,DPYSL4,ZBTB45,GUCY1B1,IDH3B,ZIC5,NIM1K,IL11RA,VWA5A,NFIX,NNAT,GLIPR1L2,POU3F4,PCDHB17P,CEP41,HKR1,SCG5,BTBD3,SLC8A3,ZNF667,PCDHGB7,PCDHGA11,PCDHB10,PCDHB9,TEK,THBS4,TIE1,BHLHB9,PRR18,ZBTB14,ZNF154,MSRB3,GAN" Coexpression M2953 Genes down-regulated in natural T reg with non-functional FOXP3 [GeneID=50943] versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 7.53E-05 8.71E-01 1.41E-03 1.40E-02 46 170 "ACADM,ACTN1,USP28,TNRC6C,SFMBT2,FOXK1,ATRNL1,PLEKHM1,KBTBD11,CALCRL,CHST15,RAPGEF6,SESN1,GGT5,TDRKH,RAPGEF4,GSTT2,IL6ST,SLC11A2,EML5,CEP97,RAD52,ARID4A,RGS10,AP1AR,SATB1,SCP2,SELL,GALNT10,ST6GAL1,ST8SIA1,SCMH1,TET1,CEP68,ADAMTS17,MGRN1,TCF7,ZEB1,PUM2,TGFBR3,SSBP2,TTC3,PMEPA1,FAM47E,ADAMTS10,KLHDC1" Coexpression M2351 "Genes down-regulated in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.60E-05 8.79E-01 1.42E-03 1.41E-02 76 321 "PITPNM2,KCNAB2,PDXK,ZSCAN18,N4BP2L1,CD81,CHM,TJP2,MAP4K4,CNN3,SLC4A7,SOCS5,DOCK2,ARRDC4,KLHL5,PLXNC1,EPB41L2,RCSD1,F5,SCML2,TPK1,KHDRBS3,DACH2,FYN,BRPF3,IQGAP2,GCNT2,GGTA1P,ADGRA3,GP1BB,TDRKH,GRB10,NR3C1,ZNF496,GSTT2,NCKAP1L,HLF,ACOT7,FGFBP3,MAN2A2,LYPLAL1,AQP11,TM6SF1,MEF2C,MEIS1,MYCN,NCF2,PBX1,PDE3B,PDE4B,CDIP1,SEPT4,CNTLN,SH3TC2,TSPY26P,ATP8B4,SATB1,ATXN1,ZFP2,SELL,PPP1R9A,DOCK10,MAGI3,NUBPL,SCMH1,BEX1,ITPRID2,CEP68,DOCK9,TGFBR3,TPD52,PDIA2,SLAIN1,WIPF1,TMEM237,SLC38A1" Coexpression M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.05E-05 9.31E-01 1.49E-03 1.48E-02 49 185 "ADD3,ANK3,MARK4,DDR1,THSD7A,CH25H,RAB33A,DNAJB5,HOMER3,CREM,CRHBP,VCAN,NCAN,RIPOR2,TOX,ZFYVE16,ARMCX2,E2F5,OPTN,ABI2,LPAR6,CALCRL,EPS8,PDLIM5,HPGDS,LILRA2,GSN,GUCY1A1,HLF,IFI16,CD200,MXI1,NPTX1,NRCAM,NTRK3,ODF2,PDE4B,MEG3,IL17RB,PALLD,SAMSN1,FBXW11,TCF7L2,ARHGEF12,SLC35G2,UCHL1,TUBA1A,FXR1,SENP7" Coexpression 16778185-Table1 Human Leukemia_Gebhard06_131genes GeneSigDB 8.22E-05 9.51E-01 1.49E-03 1.48E-02 32 105 "PCDH19,BRINP2,ZNF583,MPDZ,SYNJ2,VSTM2A,RAB3C,AKAP12,DCC,ELAVL2,ERBB4,FGF12,COQ5,GPM6A,PLD5,SCG3,PCDH8,PDE4B,IRX1,FEZF2,EPHA10,SHC4,SLITRK3,SYBU,FNBP1,PCDHGB1,RUNDC3B,ZNF610,ZFP37,KCNT2,RGMA,KCNAB1" Coexpression M10026 Genes up-regulated in NK cells: control versus acute primary viral infection. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "PLEKHG5,CNIH2,TNRC6C,RUNX1T1,SNCAIP,TCAF1,SPOCK2,CTIF,PABPC5,SRGAP3,DLG2,MRNIP,LRRC17,SYT17,SESN1,LOXL3,GRK4,GRIK5,ADAMTS6,GUCY1B1,VSIG4,CPT1C,USP54,KCNC1,MAP6,LYPLAL1,CHIC1,MITF,MYO7A,ZNF862,NOVA1,NPR2,OPHN1,OXTR,SLC25A23,LAMA1,CNTLN,RASGRF2,C12orf49,ZFP30,YPEL4,SIRT2,INTS9,ZHX3,LHFPL4,PBLD,MMS19,TNS2,CYB561A3,TRPC3,LGI4,PROCA1" Coexpression M7961 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "NDRG3,ADCY6,SORCS2,APP,ZFYVE28,BBS2,RGS11,NIPA1,CA12,CAPN3,CNN3,KIAA0040,DAPK1,ALKBH8,MTX3,TOM1,PLEKHA1,EYA1,TBC1D16,KCNMB4,GPD2,RAPGEF4,IGSF21,NIM1K,IL11RA,FGFBP3,SRSF12,MITF,AFF1,AFDN,NFIX,PFKFB2,TMIE,PMS2,FITM2,RASGRF2,BEND5,CCDC82,ATP8B4,SELL,MAGI3,CCDC88A,TET1,EPC1,RGMB,TRIO,STXBP4,TMPRSS5,SSBP2,SGK3,ZBTB16,AMZ1" Coexpression M5247 Genes up-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "SYN3,ACTN1,ALCAM,DDX3Y,MTMR9,NRP2,CFLAR,KRIT1,CLCN4,BRINP1,DYNC1I1,DPP6,ABI1,EPB41,AMOTL2,VTI1B,KHDRBS3,GAB1,ZNF44,MYOZ2,GK,ZNF638,PCLO,GRIK1,RNFT2,SYNPO,HSP90AA1,KCNJ10,KIF5C,KTN1,MT3,NF1,SLC11A2,OLR1,PAX6,PCSK5,PDE4B,PLIN1,MAPK8,RYR1,SOX15,GSE1,ARC,SYN2,DNAH7,RIMBP2,FAM155A,WIPF1,SLC13A3,ZIC3,SLC30A4,NAV3" Coexpression M7525 Genes up-regulated in double positive thymocytes stimulated by anti-CD3: ELK4 [GeneID=2005] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ADD1,ADD2,KIAA1211,WDR35,ALAD,ANK1,EPB41L5,GPAM,PLA2G4C,BCL7A,BLM,FADS2,CTH,PITPNC1,AK5,ATL1,SCML2,ATP8A1,FECH,CELF1,GAB1,C15orf41,ACSS1,DHRS4,CECR2,GRB10,ARHGAP12,GPR155,SAMD14,NEK1,PPP3CB,EPDR1,GDPD1,SLC22A23,UHRF1BP1,PEX5,SH3TC2,DZIP1,SLC12A2,SLC12A4,SNCA,TNIK,ZBTB43,SEPT8,TAL1,HIF3A,SIK3,ZMAT3,TGFBR3,TSC1,PORCN,SPIRE1" Coexpression M7290 Genes up-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "TMCC3,ADD1,GRAMD1B,ADORA2A,SORCS2,BIN1,ANXA7,KCNAB2,PHYHD1,TMEFF1,ARRB1,NRP2,B4GALT6,CDC42BPB,CRMP1,SIPA1L1,MYADM,GUCD1,RHOBTB1,SLC29A4,EXTL1,FCGRT,AK8,ACSS1,GART,TPPP,SPACA9,LRRC75A,RBPJ,LIFR,LMO2,AFDN,THYN1,NFIX,PRKCZ,PLEKHB2,RAP1GAP,RFX2,MAPK12,RASA3,SGK1,ITSN1,ST6GAL1,SIRT2,SOX5,RAP1GAP2,STAC2,TJP1,TNFRSF1B,TPD52,RGMB,TUB" Coexpression M3385 Genes up-regulated in comparison of Th17 cells versus induced regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "MTA3,OSBPL8,APC,ATP2B1,RCBTB2,RAB33A,ABCG2,SLC4A7,NCOR1,FEZ2,UBXN2A,RASSF2,MAGI2,SACS,SLC43A2,VPS26C,MEX3B,VTI1B,FOXO3,JKAMP,B4GALNT1,INPP5K,GPM6B,GPR37,GUCY1A1,GYG1,ATG4C,HSP90AA1,INPP1,FXYD7,OLA1,PKM,LRP12,ING3,SPATA6,PPP2R5E,CCDC82,ZNF354C,SUPT20H,CCDC92,FAM126B,ZCCHC24,MYCBP2,TTBK2,VAMP1,TACC1,TCF12,WASHC4,SIK3,STXBP4,RICTOR,AMN1" Coexpression M3227 Genes down-regulated in regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "AP2A1,ADGRF5,TRMT9B,FAM131A,PRX,ALDH4A1,KIF1A,RGS9,RAB29,VXN,KMT2C,LY86,CMTM5,GSDME,ABCC5,FRY,LRRC17,ZMYND10,GPR153,DENND2A,CPLX1,KCNMB4,GP1BB,GPM6B,B4GALNT4,CELF3,NXPH3,HP,SCIN,IL12A,INPP5B,MGAT3,MT3,FXYD7,SH3KBP1,PPP2R2B,NKAIN4,SLC26A11,PEX5,SLC25A41,CRTAC1,MAP6D1,RTN1,PALLD,LHFPL4,PHLDB1,PHF24,NSD1,BEX4,PRMT8,TFIP11,NHSL1" Coexpression M8980 Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and PPARg1 form of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "AP1B1,ADGRF5,FAM131A,SHROOM2,ARRB2,SLC4A4,KYAT1,KIAA1549L,NMT2,DNAJB5,PLCH2,DZIP3,EDRF1,DOCK4,RASSF2,ZEB2,MAGI2,RASGRP1,EPB41L1,NBEA,SMC2,GPR153,GPER1,CROCCP2,HTR2A,KIT,CNOT4,OLR1,PDCD2,PDE4A,SMOX,LRP12,MCMBP,AP1AR,CDK5RAP3,RCOR3,PDZRN3,ZSWIM8,UHRF1BP1L,CDK19,APOM,VPS13A,OBSL1,TNS2,ZMAT3,TGFBR3,TMOD1,BEX4,TRPC1,TTTY15,PORCN,ZSCAN26" Coexpression M5367 Genes up-regulated in comparison of untreated macrophages versus macrophages treated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "PPFIA4,CDC14B,ARNTL,DYNLL1,SCAPER,LDLRAD4,SLC25A14,IFFO1,CTNND1,SEC14L5,TM9SF4,GIT2,DDX46,SV2A,PHC2,KMT5B,EPS8,PRMT5,GABRA3,GJB1,BRD8,ADGRA3,KAT7,HMX1,INPP5B,NINJ2,PDE4A,PEX2,UBR7,CCDC82,DCUN1D2,PCMTD2,KCNIP1,ZNF821,CLSTN1,SLC6A1,ARHGEF40,CLUAP1,RBM26,PBLD,ZC4H2,FAM168A,ARHGEF9,WSCD1,R3HDM1,TRPS1,ZKSCAN5,ZNF74,RNF103,PDSS2,EPM2A,LAS1L" Coexpression M5540 Genes down-regulated in comparison of B cells versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "DDO,OSGIN2,CA8,REPS2,CDH2,MYRIP,NECTIN3,SNCAIP,OSBPL3,CST3,SDC3,CX3CR1,RASSF2,RIMS3,DBI,SIRPA,FBXL5,LYPD1,SLC12A6,ABCC5,FRY,LPAR6,EMX2,CDHR1,RTN3,SEC23B,FOXO3,SEMA4D,GLUL,GNAS,GRB10,GRIA2,WIF1,HRH3,HP,TUBB2B,MBP,NRDC,TREM2,MTRF1L,LRP12,PILRA,RFX4,PRR5L,FRMPD1,NLGN1,PALLD,POGZ,ITPRID2,ELOVL4,TLR4,PAK5" Coexpression M3877 Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ADD1,BRAP,AP2A1,APP,ARHGDIA,MARK4,BACH1,LRBA,CDH2,TMEM184B,MAP4K4,NCOR1,DGKG,B3GAT3,C2CD2L,DNM1,GOLGA7,EN2,OLIG2,EPB41L1,MRVI1,F5,FCGR3A,FHL1,ALDH1L1,MAP6,GIT1,PDE1B,PENK,TMOD2,EPN1,RETREG2,TNPO2,UHRF1BP1,RTN1,PUF60,AMBRA1,ARHGEF40,RCOR3,SOX11,VAMP1,FBXW11,KIAA0930,TPCN2,PSD3,FRYL,HEY1,TMEFF2,SF1,PCDH20,SPHK2,NT5M" Coexpression M4252 Genes down-regualted in comparison of regulatory T cell (Treg) from CBFB [GeneID=865] deficient mice versus those from wild type animals. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "AMPH,LARGE1,GPR37L1,SULT4A1,RAB26,COL9A1,MAGED1,SLC35F1,RBM39,NCOR1,CHD5,ERC2,RIMS3,DGKG,DPH1,ST8SIA3,MTSS1L,SRRM1,NCALD,CDKL3,B3GAT1,PHYHIPL,GABRA4,STARD10,GPR162,MAP7D2,PCLO,GRIK4,GRIN1,GRM2,IL1RAPL1,MITF,MOG,MDGA1,NAP1L1,SFR1,HCN1,NUCB2,PDE4A,KCTD15,VEPH1,RPRD1A,SMPD3,BTBD3,SPHKAP,KIF13A,KAZN,MTCL1,TBX15,TMPO,NAV3,RTN4" Coexpression M3163 Genes down-regulated in comparison of Th1 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ZNF687,DPY19L3,FGF17,GPC2,CCK,MAP4K4,NIPBL,AKAP7,HINFP,FGFR1OP2,BSCL2,MFSD10,VPS26C,EXTL2,ACSL4,FECH,SPECC1,DACH2,GNAS,GRIK1,SLC2A6,GYG1,DDX19B,ATCAY,CREG2,PAXBP1,MITF,N6AMT1,RTL5,PMS2,DRAM2,DEF8,PTPN13,SLC6A15,CCDC82,LRRK2,NCBP3,PDZRN3,SYPL1,PCDHB15,SPX,TIAM1,C9orf85,SLC35A4,DNAJC12,CCDC136,ZBTB14,STMN4,TUBA1A,SLC17A6,FAM219B,RSPRY1" Coexpression M5192 Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ACLY,KLRC4,OGT,DGKZ,DNAH17,ATP2B3,MYRF,CCNT1,LARGE1,SLC4A7,CRYM,FAM131B,HDAC9,TCAF1,DAPK3,DCT,SRGAP3,ECM2,ABCC5,STX2,FDFT1,FGF12,FGR,PNMA2,MTHFD2,GRIN1,ATXN2L,IGF1,ITPKA,NFIA,OPHN1,PDE2A,CCSER2,C19orf57,PRKAB2,MASP1,S100B,DOCK10,SMTN,TMCC1,UNC5B,FCHO1,SYT1,DDHD2,USP22,DICER1,LILRA4,CDK20,TRO,TRPC3,ZIC2,MPPE1" Coexpression M5683 Genes up-regulated in comparsion of ActCD8 versus ActTreg (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "GAS7,STX16,BAIAP3,CABP7,CNRIP1,FBXL5,SV2B,AASDH,IRAK4,NCALD,CACNG3,RACK1,ST3GAL6,FCGRT,GTF2IRD2,EVL,SARAF,GAB1,GABBR1,B4GALNT1,ACSS1,MALT1,OS9,RAPGEF4,P2RY13,IDNK,PAK3,PDE2A,PDE4B,PDPK1,ABCB1,NKAIN4,SNRK,EML5,PYGM,TTC13,TMEM231,SATB1,ATXN1,ZFP30,KIF21B,LHFPL4,ARHGAP26,EPB41L3,VWA3A,TCF7,FRYL,NACC2,PRRT1,TTC3,UBE2H,MPPE1" Coexpression M3479 Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus thymic stromal cells. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ACTN1,CDC42BPA,TMEFF1,BCL2L2,MTMR2,GYG2,KALRN,INA,CDH2,LARGE1,COPB2,SLIT2,KIAA1549L,HOMER3,IQCK,TENM4,LRIG1,DNAJC6,COPS7A,DNM1L,EIF4G1,EYA1,ARMCX1,PDLIM5,GSTT2,HAS2,KCNK1,LIMS1,MEST,PTOV1,SSH1,TMEM100,BAALC,RPS6KA2,SYNDIG1,RXRA,ATXN1,SCG5,ITSN1,SLC6A1,SLC6A8,ARHGEF40,ZCCHC24,DOK5,BEX1,SS18,PDLIM2,TRIM2,TGFBR3,SMUG1,TUBB2A,NAV2" Coexpression M5216 Genes down-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ASIC1,ADD1,ADORA3,OSBPL1A,DGKZ,APOC1,ASTN1,STX16,ST3GAL5,IL33,CACNA1E,CAST,USP6,AIFM1,RCBTB2,CHN2,CNOT8,IFFO1,ABCG1,PPP6R2,DAPK1,FBXL5,CDHR1,FOLR2,NPTN,LILRA2,GPR45,KCNB1,LMO2,MSR1,NRGN,ODF2,PALM,PRKACB,PRPSAP2,RXRA,MAPK12,ATXN1,EPN2,ZCCHC24,PEG10,ARHGAP26,NPAS3,IQCE,USP22,SYNE1,BEX4,TPM1,RUNDC3B,CLIP2,EVI5,SCG2" Coexpression M5893 Genes important for mitotic spindle assembly. MSigDB H: Hallmark Gene Sets (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ABR,BIN1,CDC42BPA,APC,ALS2,SHROOM2,ARHGAP5,ARHGDIA,MARK4,DST,ARHGEF7,WASF1,PRC1,ARHGEF2,CDC27,CDC42,TAOK2,DOCK4,DOCK2,ABI1,TUBD1,EPB41,EPB41L2,PDLIM5,RAPGEF6,SEPT9,CNTRL,GSN,SYNPO,KLC1,MID1,NF1,NUMA1,OPHN1,ANLN,CLIP1,ITSN1,RAB3GAP1,CCDC88A,CDK5RAP2,PALLD,SPTAN1,KIF1B,STAU1,FGD4,CLASP1,ARHGEF12,TIAM1,TRIO,TSC1,CLIP2,RICTOR" Coexpression M9180 Genes down-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943]. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ADCY6,RNF157,ARHGAP20,GPRASP2,MAP4K3,PKP4,CA8,CACNA1A,DDR1,FMNL3,ABCG1,GREB1,RIMS3,DAPK1,ANKRD46,PLEKHO1,ENO2,EPB41L2,ARMCX1,KIT,KTN1,HECTD2,SRSF12,KCTD6,MOV10,PTOV1,TMIE,SMOX,SLC25A23,PURG,CDIP1,MAPK7,ZNF354C,SATB1,ATXN2,ZNF821,RASA3,ST8SIA1,DZIP1,SPTAN1,ATP11A,MCF2L,AGTPBP1,TCF4,TCF7,TEX15,TP53BP1,TTC3,TUBB2A,TOM1L2,NDRG4,PMEPA1" Coexpression M7682 Genes up-regulated in ankle joints: SPHK1 [GeneID=8877] versus wildtype over-expressing TNF [GeneID=7124]. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "DGKZ,ASPH,DDX3Y,ATP2A2,CFLAR,SYNGR3,CDH18,NPIPA1,SRSF11,TMEM184B,MYRIP,USP6NL,DBT,SMG7,SACS,RGS17,EYA1,EFEMP1,MTHFD2,DCLK2,FERMT2,HPS5,SCIN,KLC1,SAMD14,KCTD15,MTRF1L,POU3F4,POU6F1,RASGRF1,RGS12,TTLL7,ZFHX4,MYH14,ALG9,RPE65,HUNK,RYR1,SALL1,SCN3A,FRMPD1,MAPKBP1,KIF21B,BEX1,MAPK8IP3,SYP,ROBO3,TCF7,DICER1,SLC44A1,ZNF154,LRP8" Coexpression M302 Genes up-regulated in primary bronchial epithelial cells: control versus stimulated with IL22 [GeneID=50616]. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "LRFN1,CLCN3,ENTPD4,ARHGEF4,CTNND2,CX3CR1,DAPK1,KBTBD11,DMTF1,ABI2,PLXNC1,PAN3,SLC43A2,TBC1D16,CHST15,SEMA4D,C2orf88,TACC2,CAMKK2,HHIPL1,FYB1,ILDR2,NAT8L,ERICH3,NDP,HCN1,OPA1,PLCL1,MED1,UHRF1BP1,SLC25A36,ELP2,KIF21A,ITSN1,MYO18A,DHX30,ATF7IP,TET1,CDK19,RBM26,EPB41L3,RHBDL3,CNTN2,TBX15,KIAA0930,PSD3,CRTC1,HHIP,TTC3,WNK1,SLC38A1,NLRP3" Coexpression M5195 Genes up-regulated in comparison of dendritic cells (DC) exposed to L. donovani versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ASIC1,ACTN1,AMPD2,APOC2,AQP4,CCDC181,CACNA1E,LDB2,SLC16A4,P2RX6,ENTPD2,CHRNA4,CRHBP,ATRNL1,ZNF804A,FBXL5,SPOCK3,ENO2,LRRC17,ZNF391,FOLR2,NPTN,GFER,GNAL,STON1,NXPH3,HMX1,SMAP1,KCNB1,KIF5A,KIFC3,KTN1,MAG,MBP,ADAM11,MYH6,NKX2-2,ODF2,RPE,EPN2,LIMCH1,SP4,ACSBG1,SYT11,ANKRD28,SMG6,TMEM151B,DNAH7,LEFTY2,RUNDC3B,VSNL1,PRDM2" Coexpression M4980 Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 0 versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "KIAA1324,ABCD2,MARCH3,ASTN1,CDK5R1,WASF1,RUNX1T1,CDH2,TAOK2,TPP1,ENTPD4,ATRNL1,KIAA0040,IP6K1,MAMLD1,EGFR,TENM1,NCALD,TUBB4A,SCARA3,TBR1,DENND2A,SIGLEC8,GHR,LYVE1,GRIN1,RNFT2,SYNPO,KCNA6,KCND2,LMO1,NFYA,KCNK10,ENPP2,ABCB1,PMP2,PKIA,PRODH,MTMR10,PTHLH,PTPN13,C1orf109,GAL3ST4,SYBU,RCOR3,MBD5,KANK1,ANKRD12,TCF4,UGT8,WNT7A,ZNF37BP" Coexpression M6188 Genes up-regulated in C57BL6 CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ASPHD1,SORCS2,SMIM17,KCNT1,ANK3,CADPS,INSYN2B,BBS2,BMP7,IL33,CH25H,CLTB,CNN3,SUSD5,PPP6R2,SEC14L5,HDAC9,ACY3,GRIN3A,ABCC9,CELSR3,ELN,RABEPK,CAP2,GAD2,GGT7,INSM2,DCLK2,FUT10,GRIA2,PTPRT,RABL2A,GUCY1B1,WIF1,ATG4C,ENPP2,NLE1,TMEM231,RAP1GAP,RGR,KIRREL1,IL17RB,CABCOCO1,IZUMO4,CNTN2,BEX4,NPL,SYNPO2,RFTN2,ELFN1,SCG2,CBLN2" Coexpression M8294 Genes up-regulated in lupus susceptibility locus Sle2c1 B lymphocytes from: peritoneal cavity versus spleen. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "ADD3,BIN1,AMT,PLA2G4C,CADPS,RHBDL1,CDC25B,DLGAP1,ASIC3,PPT2,SEC31B,SIRPA,SNAP91,DMPK,DOCK2,OPTN,SORBS3,TENM1,TNK2,MRNIP,RASGRP2,TAOK3,FCGRT,TRAF3IP2,GAD2,USP19,STARD3,CIT,KAT7,PADI2,C2orf72,IL11RA,AFDN,MMP16,MYO6,PCBP3,NUMA1,OCRL,PENK,PLCD1,PLXNB3,PYGM,SGK1,ITSN1,CPEB3,VAMP1,MCF2L,RALYL,THRA,ZKSCAN5,VSNL1,GDPD5" Coexpression M3012 Genes up-regulated in comparison of naive versus effector CD8 T cells at the peak expansion phase (day8 after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "CLK4,ADCY6,AMPD3,MAP4K3,APP,CASK,ARRB1,CFLAR,MAP7,CNN3,ABCG1,RABGAP1L,ABCC5,PLEKHA1,RPS6KC1,RACK1,CAMSAP1,EVL,NSG2,ZMYND11,SRCAP,SESN1,GSN,IL6R,IL6ST,SMAD1,MAT2A,MDM4,PTOV1,CNOT4,SLC11A2,NUMA1,PKD1,RETREG1,EML5,ZYG11B,WLS,CLIP1,SATB1,SELL,FAM102A,ST6GAL1,DHX30,ZKSCAN3,MYCBP2,STX1A,TCF4,TCF7,SLC44A1,SSBP2,TTC3,EVI5" Coexpression M5724 Genes down-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus untreated NK cells. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "AS3MT,ESYT2,CARNS1,CPNE5,MARCH3,ZBTB10,ATP6V0A1,CAMK2D,CBLN1,AKAP5,CNRIP1,ABCG1,PHACTR3,CX3CR1,RIPOR2,CPEB2,TMTC1,PLXNC1,NCALD,ZIC4,FOXO3,PSD2,PHYHIPL,ZNF274,ACSS1,GLUL,KLF12,BACH2,MAG,MSR1,NRCAM,ABCB1,SERPINI1,PTH1R,IQSEC3,ZNF493,OXR1,ZYG11B,RFX5,PCMTD2,KCNIP3,WLS,ATXN7,TET1,SMARCD3,USP33,FAM219A,KIF1B,SYNE1,CCDC173,TRPS1,RICTOR" Coexpression M6030 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus IL4 [GeneID=3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "METAP1D,TBC1D14,PITPNM2,CDK10,TMEFF1,ARRB1,CAPRIN2,ZBTB10,SYNJ2,CD86,AKAP7,SLC4A8,AHCTF1,ZFP28,UBXN2A,KIAA0753,SRGAP3,CDON,E2F5,PLEKHO1,TESK2,KIAA1109,FLYWCH1,SORBS1,TPK1,STARD10,KDM2B,DIPK1A,KIF2A,TTYH2,MEST,PPM1L,ETFRF1,PLEC,ANKRD16,PRKAB2,PXK,RAP1GDS1,REV3L,DGLUCY,SCAF8,NUBPL,SLC9A5,EPC1,SS18,IQCE,TCF4,CYB561A3,ZNF346,RFTN2,MICU3,CAB39L" Coexpression M7472 Genes down-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "OSBPL1A,GPRASP2,CDC14B,SPTBN4,BACH1,LDHD,SGCE,SEC24C,PDE4DIP,DGKG,DLG2,FRY,ENO2,MED12L,FGF11,FHL1,NBEA,MSANTD4,GBX2,ALDH1L1,GHR,PPARGC1A,GLUL,ADGRA3,PRRC2B,FICD,USP54,CD200,ADAM22,MYCN,ZNF862,NAP1L3,NPR2,OCRL,PBX1,RASGEF1B,WBP1L,CASTOR1,OXR1,TTLL7,RNASEL,ITSN1,PALLD,MPRIP,TIE1,BHLHB9,STXBP4,TTC3,VLDLR,EMX2OS,PLSCR4,KLHDC1" Coexpression M5024 Genes down-regulated in comparison of SP1 thymocytes versus SP2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.38E-05 9.69E-01 1.49E-03 1.48E-02 52 200 "NDRG3,ADD3,ADORA1,ARHGAP20,AMPD3,ANK2,PKP4,ST3GAL5,CAST,CCKBR,CD86,CRMP1,C1QL2,CSNK1G3,SDC3,EGFR,EPHA5,NRN1,FGF12,PSD2,FOLR2,HVCN1,KHDRBS3,TMEM151A,GRM8,ADAMTS6,LRRC75A,ITGAM,KCNA6,LSAMP,C2orf80,MAP2,IGSF11,PDE3B,TMIE,POU3F2,PPP3CC,PTHLH,PTX3,RASA3,KDM4D,CPEB4,SOX11,SPTB,MLC1,SYNE2,RGMB,UGT8,ZFP41,PPP1R3F,PARP11,KLHDC1" Coexpression M14566 Genes up-regulated in HMEC cells (primary mammary epithelium) upon expression of both of TP53 [GeneID=7157] and the transcriptionally active isoform of TP63 [GeneID=8626] off adenoviral vectors. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.45E-05 9.77E-01 1.50E-03 1.49E-02 53 205 "ABHD6,APAF1,TNRC6C,ARRB1,MARCH3,KSR1,CABP7,CAPN3,NPIPA1,SLIT2,ARHGEF6,WHRN,COL9A3,ZNF385A,PPP1R16B,TOX,RASGRP1,FRY,APC2,FGF13,FOXF2,SEMA4D,DPYSL4,OGA,GPT2,GPR37,UBE2QL1,SHISAL1,KCNK3,SMAD9,MX1,NPTX1,PCSK5,PLCD1,EPB41L4B,PPP2R2C,PTX3,RET,HUNK,SOX8,ELMOD1,ARX,SHC4,NBPF1,ZCCHC24,UNC5B,EPB41L3,TACC1,ZIC2,REEP1,STOX2,ST8SIA2,SPATA13" Coexpression M6122 "Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 20 h time point that were not up-regulated at the previous time point, 18 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.48E-05 9.81E-01 1.50E-03 1.49E-02 60 240 "ABAT,GAS7,CCDC181,ATP1A3,HCN2,BTRC,USP6,CDC42,CLGN,CBARP,AHCTF1,CLOCK,ERC2,USP6NL,ARHGAP32,RABGAP1L,E2F6,EN2,ZNF391,KHDRBS3,CELF1,GAB1,TOX3,STARD3,GPR37,GUCY1B1,ATXN2L,INPP1,KCNH2,KIF5C,MAPT,MPP2,NRGN,NTRK2,PAK3,PCDH9,PDE4A,ABCB1,PLCL1,SEPT4,PPARA,PROX1,SNRK,PTPRB,PTPRD,PTPRE,RET,SLC6A8,SEPHS1,SOX5,ZBTB43,NACAD,TTBK2,WWC1,AGTPBP1,TIAM1,TMPO,CDK20,UBE2H,UBE3A" Coexpression M7105 Genes up-regulated in CD4 [GeneID=920] T cells treated with halofuginone [PubChem=400772]: 3h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 8.55E-05 9.89E-01 1.51E-03 1.50E-02 45 166 "MTA3,TAOK1,SFMBT2,INSYN2B,TMEM108,ATP2B1,BBS2,C1QC,SYT6,SLC16A4,CLTB,ABCG1,SDC3,CENPL,MAML1,ARMCX2,ZC3H11A,PTK2B,TAOK3,FECH,TRAF3IP2,GSN,L1CAM,MATK,MDM4,MITF,MX1,P2RX7,PDE1B,PLEC,MTMR10,RNASEL,RXRA,SEMA6D,IL17RB,SEC31A,KDM4B,MAPK8IP3,TCF7,TGFBR3,DDHD1,TSC1,MICAL1,WNK1,ITM2C" Coexpression M15835 Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.55E-05 9.90E-01 1.51E-03 1.50E-02 56 220 "SERPINA3,ABAT,ACADM,ALCAM,APBB2,SHTN1,CASK,AZGP1,LRBA,CLGN,UBE2L6,PLEKHB1,CNN3,CNR1,GREB1,CTNND2,MFAP3L,RABGAP1L,TSPAN5,EEF1A2,VPS13B,WAC,PDLIM5,ATP8A2,NFU1,RBPJ,IL6ST,KIF5C,LAMP2,ARHGAP12,MMP16,MXI1,NRCAM,PIK3R1,RETREG1,SNRK,ELOVL2,RPS6KA2,AP1AR,DGLUCY,ATXN1,IL17RB,HSPA4L,SYBU,BTBD3,EFHD1,PALLD,CLUAP1,PEG10,PLCB1,SYT1,TACC1,SATB2,PSD3,FRYL,PHTF2" Coexpression 16178058-Table5 Human Brain_Coco05_32genes GeneSigDB 8.65E-05 1.00E+00 1.52E-03 1.51E-02 14 31 "CDC42BPA,ASPA,LGI1,NRXN3,DMD,CHL1,MBP,PCSK1,PLP1,PMP2,PTPRZ1,S100B,SST,PSD3" Coexpression 15090461-Table3 Human StemCell_Wagner04_36genes GeneSigDB 8.65E-05 1.00E+00 1.52E-03 1.51E-02 14 31 "PROM1,ELN,FCGR3A,FHL1,GUCY1B1,IFI16,ABCB1,SELL,SLC2A5,SPP1,RGL1,NUDT10,PLCB1,LAT2" Coexpression M2945 Genes up-regulated in activated T lymphocytes: T conv versus natural T reg. MSigDB C7: Immunologic Signatures (v6.0) 8.78E-05 1.00E+00 1.54E-03 1.53E-02 46 171 "ACTN1,ADCY6,USP28,TNRC6C,SFMBT2,ARHGDIG,CACNB2,MAP4K4,IPCEF1,RIMS4,HDAC4,TOX,ECM2,PLEKHA1,CHST15,RAPGEF6,SESN1,PCDH17,GGT5,TDRKH,RAPGEF4,AGFG1,DISP2,IL6ST,SLC35G1,SMAD1,MTR,PIK3C2A,VPS13C,PTK2,EML5,CEP97,BEND5,RGS10,AP1AR,SELL,ST6GAL1,SLC4A3,TET1,ARFGAP1,TNIK,TGFBR3,SSBP2,OSBP2,TOM1L2,PMEPA1" Coexpression 16042785-tableS4 Human Prostate_Oudes05_66genes GeneSigDB 8.86E-05 1.00E+00 1.55E-03 1.54E-02 22 62 "CPNE2,DDO,ZSCAN18,ZNF555,CPS1,CNTNAP2,DTNA,TSPAN5,MBNL2,ETV1,NRG3,PCDH11X,PCLO,PARD3B,JAKMIP1,ZIK1,MARCH1,SUSD4,TTLL7,ZSWIM8,MCF2L,SPHK2" Coexpression 16473350-Table2 Human Brain_Jrgensen05_19genes GeneSigDB 9.08E-05 1.00E+00 1.59E-03 1.58E-02 8 12 "TMCC3,B4GALT6,CNTN1,LRRC3B,EPHA5,TOX2,SLC10A4,CBLN2" Coexpression 18757432-Table2a Human Breast_BernardPierrot_74genes GeneSigDB 9.10E-05 1.00E+00 1.59E-03 1.58E-02 21 58 "ADD3,SYT13,DPY19L3,CALM1,HDAC4,RCAN1,SYT15,GPR153,GLDC,HSD17B1,IL6ST,KIF5C,IL17D,MXI1,PPARA,PTPRG,RAP1GAP,SUSD4,SH3BP2,IFT122,TMCC1" Coexpression 16397240-SuppTable5 Human Colon_Grade06_85genes GeneSigDB 9.10E-05 1.00E+00 1.59E-03 1.58E-02 21 58 "ABCF1,FZD9,UNC5A,ADGRF5,LDB2,UBE2L6,AKAP6,FGFR1OP2,DGKB,FABP7,MED12L,ZDHHC15,HP,DISP2,MSR1,MYCN,HMGCLL1,PMP2,ZNF568,SOX10,ZXDA" Coexpression 15150091-Table2 Human Leukemia_Schaefer04_54genes GeneSigDB 9.23E-05 1.00E+00 1.61E-03 1.59E-02 20 54 "ADRB2,KCNAB2,ATP1B3,CAPN3,LRRFIP1,RAB33A,CREM,CTH,ZFYVE16,FGFR1,PRUNE2,GYG1,HSD17B1,ITPKB,MBP,MITF,PLP1,SH3BGR,SOX10,TACC1" Coexpression M18630 Genes in the most frequently homozygous deleted loci in a panel of glioma cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.23E-05 1.00E+00 1.61E-03 1.59E-02 20 54 "CPNE2,KLHL32,SFMBT2,BBS2,ARHGEF7,FAM19A5,FHL5,ZEB2,GNAO1,NUDT21,NXPH2,HNMT,ITIH2,KCNMA1,LRP1B,POU3F2,PTPRE,FAM192A,SOX1,NUTM2A" Coexpression M4308 "Genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.35E-05 1.00E+00 1.62E-03 1.61E-02 94 418 "SYN3,APBB2,APOC2,BARD1,KSR1,SYNJ2,CACNA1G,CACNA1A,CCK,SLC16A4,CDH8,CDO1,B4GALT6,LHX2,TJP2,CNN3,CABP1,NCOR2,CLIP3,CSF1,ARHGEF4,NOS1AP,DAPK1,GIT2,DNAJC6,CNIH3,SIDT2,RGS17,SRPK3,LRRC23,SIRPB1,EFEMP1,ZMYND10,FGFR3,SCARA3,CAMKK2,KHDRBS3,B3GAT1,SRCAP,ADAM28,HPGDS,GLDC,GPER1,AP4S1,HSD17B1,ITGA7,MGAT3,CD200,MX1,NEFH,NNAT,NPTX1,NPTX2,NRGN,PAX6,PCDHGC3,PDE2A,PDYN,PFKFB4,PLXNB3,PSAT1,SAMD9,PTX3,SUSD4,KLHL11,MEG3,SALL1,MRAS,ITSN1,SLC6A11,SLC9A5,SLC12A4,EFHD1,SNAP25,ZCCHC24,KIF21B,CLSTN2,NXT2,MAPK8IP3,ROBO3,HIF3A,HEY1,NR2E1,TNNT1,RPRM,FAM155A,UCHL1,DNAJC12,LMF1,WNT7A,MKRN3,FAM182B,NETO2,JPH3" Coexpression M2186 "Genes down-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.40E-05 1.00E+00 1.63E-03 1.62E-02 43 157 "PLEKHH1,CACHD1,ASTN1,INSYN2B,ATP1A1,KSR1,BMPR1B,OSGIN2,CBS,SRSF11,RAB33A,PPT2,AKAP7,GREB1,TOX,MFAP3L,USP3,ARRDC4,DUSP9,RACK1,FDFT1,OLFM1,SUCO,FAM49B,GABRA1,GPD2,MFSD2A,HSD17B1,LIFR,JAKMIP3,LYRM9,NPR2,HCN1,PCDH18,MAPK9,MASP1,ELOVL2,SUSD4,MEG3,MAPKBP1,CHST8,LRP8,RGS7BP" Coexpression M1121 Genes down-regulated in brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.45E-05 1.00E+00 1.64E-03 1.63E-02 11 21 "FAM131A,SYNGR3,CHN1,CALY,CTNND1,PPP1R1B,ACOT7,PPP3CA,PRKCZ,RPH3A,SLC30A3" Coexpression M2633 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable EGFR [Gene ID=1956]. MSigDB C6: Oncogenic Signatures (v6.0) 9.54E-05 1.00E+00 1.65E-03 1.64E-02 51 196 "CLK4,ADD3,KIAA1324,ANK3,APBB2,ASCL1,ZSCAN18,MPDZ,CALB2,PTBP2,KRIT1,CHN1,COL9A3,GREB1,TCAF1,TSPAN5,RASGRP1,EGR3,EPB41L2,EPS8,ARMCX1,DLC1,PCYOX1,GALC,GFRA1,GPER1,GRB10,ELOVL5,KIF5C,MATN2,NDUFA5,FTO,PRKACB,ELOVL2,PCMTD2,HSPA4L,EFHD1,ATF7IP,SOX3,PEG10,ITPRID2,DMXL2,SATB2,METTL3,HIRA,SGK3,CADM1,DNAJC12,WIPF1,SH3GLB2,MFF" Coexpression M15535 Genes up-regulated in UB27 cells (osteosarcoma) at 12 hr after inducing the expression of a mutated form of WT1 [GeneID=7490]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.70E-05 1.00E+00 1.67E-03 1.66E-02 44 162 "ABAT,ADORA1,MTUS1,AMPD2,CASK,ARHGDIA,CA12,DDR1,ADGRG1,CS,CSF1,PLEKHO1,ENO2,EPS8,FGF1,FGFR1,FGFR3,OGA,SEPT9,CSDC2,GLI2,FERMT2,GRB10,KCNK1,MN1,MYCN,PDGFRA,PLCD1,PPP3CA,RIPOR1,TMEM255A,OXR1,LGR4,SCNN1D,ST8SIA1,SON,ZCCHC24,PSD3,SLC35G2,RBFOX2,RUNDC3B,ZMYND8,SYNC,SLC17A7" Coexpression 19880498-TableS6 Human Leukemia_Kang09_352genes GeneSigDB 9.71E-05 1.00E+00 1.67E-03 1.66E-02 58 231 "ADCY6,AP1B1,PITPNM2,APBB2,DGKD,LINC00173,DCAF5,PROM1,BMPR1B,WASF1,CAMK2D,PRC1,CD38,RCBTB2,NRXN3,NMT2,AKAP12,TENM4,OSBPL3,CSNK1G3,CYBB,RASSF2,RIMS3,DAPK1,DBN1,E2F5,LPAR6,EPB41L2,ARMCX1,AMZ2,MPP6,RAB30,ADGRA3,GUCY1A1,GYG1,IRAK3,TOX2,BACH2,TTYH2,LMO2,SMAD1,ZNF92,NPY,PCDH9,PDE4A,SCHIP1,BAALC,PRR5L,RCOR3,FNBP1,RAP1GAP2,SAMSN1,ANKRD28,AKTIP,PARD3,TPM4,LMF1,KCNK12" Coexpression M250 Genes down-regulated in macrophages by P.gingivalis FimA pathogen. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.86E-05 1.00E+00 1.70E-03 1.69E-02 68 282 "CSMD2,NDRG2,CCDC85A,PPFIA4,DGKZ,GPAM,ASCL1,PRMT9,CACNB2,ZNF555,USP2,SLC16A4,RCBTB2,ZBED5,CNOT8,CPNE6,NRXN3,IFFO1,CPS1,DBT,SGSM2,RABGAP1L,ECM2,LPAR6,ELAVL3,ACTL6B,TMEM107,ZNF605,AP4B1,RAB40B,MCHR1,MUM1,KLHL23,ARHGAP12,SMAD1,AQP11,MBP,SHC3,THYN1,PRIMPOL,CYBC1,PTPRO,MARCH1,ARID4A,RPE,ZC3H14,SCN7A,CHD9,CNKSR2,ST3GAL3,YPEL4,ARHGEF40,TMCC1,GLT8D1,FGD4,PCDHGC5,ARHGEF12,ENHO,HIRA,WIPF1,ZBTB14,ZNF540,REEP1,CA10,LINC00632,JMJD1C,NHSL1,DPF3" Coexpression M2157 Genes down-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.97E-05 1.00E+00 1.71E-03 1.70E-02 110 505 "ACHE,ALCAM,CDC42BPA,ANK3,SEMA7A,EPB41L5,BCAS1,SFMBT2,ARHGAP5,ATP2B1,DOCK11,BMP7,OSGIN2,LDLRAD4,CAST,USP2,CDH2,DCLK1,SLIT2,TJP2,ABCG2,QKI,MAP4K4,SLC4A7,FAM171B,ABCG1,DZIP3,PNPLA8,CTNND2,FAM131B,MYADM,KIAA0513,DAPK3,DBN1,CPEB2,RCAN1,ABCC5,EDN1,KLHL5,OPTN,PHF20L1,AASS,EPB41,EPB41L2,ERBB2,ADGRV1,RPS6KC1,SH3YL1,TAOK3,ATP8A1,KIAA1109,NBEA,PDLIM5,FAM49B,TRIM16,GAB1,CAB39,RND1,FERMT2,LNX1,STON1,GPR37,KIF3A,GUCY1A2,UBE2QL1,SYNPO,ITGAV,KCNJ3,KIFC3,L1CAM,ARHGAP12,NCOA7,MAP2,MATN2,MID1,MMP16,SESN3,MYO6,RTL5,NCF2,PCDH9,XRN1,SCHIP1,PPP3CC,SYTL2,ZSCAN2,FAT4,GALNT10,ABLIM3,EFHD1,CPEB4,INAVA,LIMCH1,LMBRD1,PALLD,KDM3A,RAP1GAP2,RGL1,PHLDB1,TACC1,MTCL1,PSD3,BEX4,TPM4,UBE2H,TOM1L2,PMEPA1,EVI5,MSRB3,FRMD6" Coexpression M6700 Genes up-regulated in endothelial cells: interferon alpha versus interferon beta. MSigDB C7: Immunologic Signatures (v6.0) 9.97E-05 1.00E+00 1.71E-03 1.70E-02 45 167 "ADD3,ARNTL,MARCH3,DPY19L3,GPR146,DDR1,LARGE1,RCBTB2,PLEKHB1,FBXO7,VAX2,CNN3,CRMP1,DGKG,ARMCX2,HP1BP3,NR1D2,NCALD,ST6GALNAC3,ABLIM2,ATP8A2,GGT5,TTBK1,TDRKH,RAPGEF4,ITGA7,KIT,SERPINI1,JAKMIP1,PRKACB,PRKCB,SLC26A11,BCAS3,RGS10,RASA3,ABTB1,WDTC1,ACSBG1,SYNE2,PSD3,SYNPO2,AMACR,MEIS3,PARP6,KLHDC1" Coexpression 20436685-ST6-2 Human Breast_Pothuri10_180genes GeneSigDB 9.97E-05 1.00E+00 1.71E-03 1.70E-02 45 167 "AK2,OGT,MARCH3,ADAM23,MAP7,ZMYM4,ZBED5,CRYBB1,SOCS5,SLITRK5,TCAF1,DNAJC6,MAGI2,GNE,RASGRP1,FRY,FAM13A,VPS13B,KCNMB2,NCALD,FUT9,GAD1,GK,GLS,GPR37,IRF8,MARK1,MEF2C,PLCL1,PRKACB,RAD17,SLC25A36,BAALC,CASC3,FNDC3A,ST8SIA1,SOX2,SOX3,UHRF1BP1L,RBM26,SEPT8,KLHL4,EHBP1,DNAH7,VIPR2" Coexpression M3238 Genes up-regulated in bone relapse of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.01E-04 1.00E+00 1.72E-03 1.71E-02 30 97 "ABAT,BCAS1,ASCL1,CA12,REPS2,DCLK1,CLGN,SLC4A8,ATRNL1,PDE4DIP,FGFR3,EVL,GFRA1,RND1,TOX3,PTPRT,GSTT2,KIF5C,MATN3,LRP1B,NELL2,PAH,RETREG1,FAIM2,SEPT8,SYT1,PSD3,TIMP4,DNALI1,SEMA3B" Coexpression M2442 Major erythrocyte membrane genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.05E-04 1.00E+00 1.79E-03 1.77E-02 9 15 "ADD1,ADD2,ADD3,ANK1,EPB41,DMTN,SPTB,TMOD1,TPM3" Coexpression 20096135-Table2 Human Liver_Utispan10_75genes GeneSigDB 1.05E-04 1.00E+00 1.79E-03 1.77E-02 24 71 "NME5,ADGRF5,NRP2,CDH10,DCLK1,ZEB2,SPOCK3,EBF1,SEMA3D,PCOLCE2,GAP43,MYOZ2,PCDH17,ITGA7,KIT,MATN2,PDE1A,ENPP2,RELN,PTHLH,PTPRO,CNTNAP3,TNFRSF19,PKNOX2" Coexpression M6767 Genes down-regulated in atypical ductal hyperplastic tissues from patients with (ADHC) breast cancer vs those without the cancer (ADH). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.06E-04 1.00E+00 1.80E-03 1.79E-02 38 134 "SERPINA3,LTBP4,CDK10,ALDH4A1,AZGP1,DST,CA12,CACNA1D,CAPN3,CRLF1,COL4A5,DCT,AK5,SEZ6L2,EDN3,ERBB4,FABP7,FGFR3,DKK3,SYT17,GFRA1,GRIA2,WIF1,IGSF1,ITGA7,MAPT,MATN2,OXTR,PIK3R1,PTN,IL17RB,KDM4B,EXOC7,TF,KCTD2,TPM2,DNAJC12,NAV3" Coexpression 21205295-TableS5 Mouse Viral_Buonomo11_202genes GeneSigDB 1.06E-04 1.00E+00 1.80E-03 1.79E-02 38 134 "CDC7,ASCL1,PROM1,CDK5R1,WASF1,CBFA2T2,CDC25B,CHGB,CRMP1,CRYM,DMD,ERBB2,SMC2,TRIM16,TPPP3,MTHFD2,DBF4,PSIP1,FAM107A,HLF,ACOT7,INSM1,KIF5C,MAOB,MEST,NCAM1,NOVA1,PCSK1,PCSK5,RBBP8,RTN1,SCG5,STXBP1,SYT1,TGFBR3,USP1,NSD2,SLC38A1" Coexpression M939 Genes up-regulated in hematopoietic progenitor cells (HPC) of B lymphocyte lineage CD34+CD45RA+CD10+ [GeneID=947;5788;4311]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-04 1.00E+00 1.81E-03 1.80E-02 70 293 "KDM5D,AP1B1,SEMA6A,CDK13,ZBTB10,DDX3Y,ATM,BARD1,ARHGEF7,LDLRAD4,DDR1,CALM1,CAPN3,HIP1R,ABCG2,MAP4K4,ENTPD4,AKAP12,LRIG1,ZFYVE16,RIMS3,DBN1,E2F5,RASGRP1,KMT5B,CORO2B,CHST15,RASL10A,ARPP21,ADGRA3,GPM6B,LILRA2,BTN2A1,RNFT2,BACH2,AGFG1,SMAD1,MEF2C,MOG,NPY,PCDH9,DUSP26,PIK3CD,RETREG1,SCHIP1,PPM1B,PPP3CC,PKN2,PTPRE,TTC13,RAD52,MSANTD2,SCN3A,SMARCA4,KIF13A,TMCC1,ZNF423,VAMP1,VPS13A,COBL,TCF4,WASHC4,PSD3,TPD52,SSBP2,LMF1,ZNF177,PRDM2,HPS4,JMJD1C" Coexpression M2977 Genes up-regulated in peripheral blood mononclear cells (PBMC) from multiple sclerosis (MS) patient: untreated versus IFNB1 [GeneID=3456]. MSigDB C7: Immunologic Signatures (v6.0) 1.11E-04 1.00E+00 1.89E-03 1.88E-02 39 139 "AS3MT,ELFN2,HHATL,SORCS2,CNIH2,RGS11,CACNA1G,SULT4A1,PLCH2,CX3CR1,ZEB2,EDNRA,FCGRT,EVL,CGREF1,TPPP3,ADAM28,TNFAIP8L3,DISP2,JAK1,HECTD2,CTNNA3,CLDN11,SDK2,NXPH1,SLC22A23,FAM184A,PREX2,DIP2A,PCDHB6,TRPM2,NTSR2,ZBTB16,TMEM237,MEIS3,URM1,SSPN,FAM198A,JPH3" Coexpression 12890387-Table2 Human Leukemia_Wang03_43genes GeneSigDB 1.13E-04 1.00E+00 1.91E-03 1.90E-02 16 39 "OGT,HOMER3,SV2B,STX2,EVL,GSN,KIF3A,ASPRV1,MDM4,PKIA,PEX5,RTN1,DDHD2,ZKSCAN5,PRDM2,MARCH8" Coexpression 18794137-SuppTable1e Human Breast_Creighton08_643genes GeneSigDB 1.16E-04 1.00E+00 1.96E-03 1.95E-02 101 458 "MTA3,MTUS1,ALAD,ALCAM,ANK3,BCAS1,SFMBT2,PDXK,NCOA1,RASL11B,ATP2B1,DOCK11,DCAF5,BMP7,SYNJ2,HIP1R,RUNX1T1,CFL2,COPB2,SOCS6,CLTC,TJP2,QKI,CTNND1,CTNND2,RUBCN,DBI,MFAP3L,FBXO25,SGSM2,CPEB2,ABCC5,PHF20L1,GOLGA7,EML1,VPS13B,EPB41L2,ERBB2,ERBB4,FAM198B,ATP8A1,FGF12,FGF13,USP16,GAB1,CAB39,MALT1,LNX1,GRB10,DIDO1,GSN,ZHX1,ICA1,INPP1,KCNMA1,LSS,MATN3,MBNL1,COL28A1,CCDC80,NCAM2,NF1,PCBP3,SLC11A2,NUCB2,ZNF827,PBX1,PMP22,STRN3,EPB41L4B,NXPH1,PTPN13,RIPOR1,ZDHHC4,SGSM1,WLS,GALNT10,WDR37,SHANK2,SLC12A2,NAXD,LIMCH1,PDZD2,FNBP1,RAP1GAP2,NXT2,KLHL7,TACC1,TCF4,PSD3,AKTIP,NACC2,BEX4,RPRM,GORASP1,TBC1D15,RICTOR,REEP1,SPIRE1,RNF103,CAB39L" Coexpression 17597811-SuppTable2 Human Leukemia_Mullighan07_444genes GeneSigDB 1.20E-04 1.00E+00 2.02E-03 2.00E-02 86 378 "ACLY,ADAR,AK2,LTBP4,ALK,DGKD,FAM131A,CAPRIN2,ATM,CFLAR,CDK5R1,DST,CACNA1I,CA12,CACNA2D1,CAPN3,RUNX1T1,CHGB,TJP2,NIPBL,CNR1,WHRN,COL4A5,CS,DZIP3,PPP1R16B,CTH,SCRN1,IP6K1,FEM1B,EEF1D,FRY,MBNL2,LPAR6,PLEKHO1,DLC1,ZMYND10,FHL1,FOXO3,CAMKK2,GAD1,ARFIP1,PPARGC1A,GK,GPM6B,MCHR1,KIF3A,HMGB1,AGBL5,HSP90AA1,LIMS1,MAN2A2,MEIS1,CD200,NBL1,NCAM2,NFE2L2,CNOT4,PCDHGC3,PDE2A,PDE3A,PDE4D,SNX10,RETREG1,SCHIP1,POU6F1,PKN2,PSMA6,APTX,SNRK,PTCH1,SPDL1,LGR4,ASRGL1,SH3BP2,EMC1,SPTAN1,SRPK2,ZFR2,IQCE,TCF7,DOCK9,CHST5,KCNE5,TST,WNK1" Coexpression M16922 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing t(9;11) translocation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.20E-04 1.00E+00 2.02E-03 2.00E-02 37 130 "ABAT,AK2,APOC2,ADAM23,LDLRAD4,CNOT8,FEZ1,ZEB2,FCGR1A,FLT1,ERAP1,GFRA1,HSF2,IDH3A,ITGA7,MDM4,MEF2C,MEIS1,MYO6,NTRK3,PENK,RAD17,RBBP6,SLC25A36,RYR1,SATB1,ATXN1,FRMPD1,PALLD,SRPK2,CLASP2,TBL1X,CLASP1,SF1,INTS3,EVI5,JMJD1C" Coexpression 17952122-GeneList Human Breast_Vecchi08_792genes GeneSigDB 1.20E-04 1.00E+00 2.02E-03 2.01E-02 118 551 "SERPINA3,ABAT,ADD3,OSBPL8,SPARCL1,SRPX,BBOX1,ASPH,ZSCAN18,DOCK11,AZGP1,PROM1,DST,RAB29,IL33,CA12,CLGN,CHN1,SLIT2,NMT2,LY86,CNN3,RBM39,VCAN,BOC,RIPOR2,HEPH,GSDME,SEC16A,CHRDL1,ECM2,DYRK1A,EDIL3,EDNRA,RASGRP1,RBM12,LRRC17,ETV1,EFEMP1,ATP8A1,DKK3,RAPGEF6,IQGAP2,SEPT9,HPGDS,GLS,TOX3,FERMT2,GPM6B,NR3C1,PSIP1,HBA1,HNMT,IRF8,IGF1,JAK1,KIF2A,KIT,LAMP2,PIK3AP1,MBNL1,MBP,MEF2C,NBL1,NELL2,CLDN11,PDE3B,PDE4B,PDGFRA,GNG2,PIK3CD,ZFYVE21,PCDH18,PMP22,PRRX1,PPP2R5C,PPP3CA,RASGEF1B,PRKACB,PRKCB,VPS13C,PTN,RGS4,PNMA8A,SATB1,SELL,SGK1,SCG5,DOCK10,ST6GAL1,ARHGEF40,SMARCA4,PALLD,KDM4B,SON,FNBP1,DOK5,MYCBP2,SPP1,SAMSN1,ERBIN,TAC1,TACC1,ANKRD12,TBL1X,TCF4,DMXL2,TCF7L2,ZEB1,PUM2,FRYL,HEY1,TPM1,CADM1,VSNL1,REEP1,SLC38A1,TUBA1A" Coexpression M8898 Genes down-regulated in CD4 [GeneID=920] versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.21E-04 1.00E+00 2.02E-03 2.01E-02 47 178 "GRAMD1B,MARCH3,LDHD,CD86,ABCG2,MAP4K4,LRIG1,IPCEF1,GALNT9,CDON,FSD1L,EVL,GFRA1,DCLK2,RAPGEF1,ADAMTS6,ATXN2L,ITPKB,SMAD1,SESN3,NACA,NF1,SLC11A2,P2RX7,PDE4B,PENK,PLCB2,SH3KBP1,PPP3CC,RBBP6,RFX5,RIMKLA,RXRA,SEMA6D,IL17RB,GALNT10,SH3GL3,ST6GAL1,ST8SIA1,ARHGAP26,SEMA4A,TCF7,TIAM1,TTC3,VIPR2,SLC38A1,TMEM63C" Coexpression M5388 "Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 18 h time point that were not up-regulated at the previous time point, 16 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.21E-04 1.00E+00 2.02E-03 2.01E-02 47 178 "ABAT,PPFIA1,CCK,CDC27,CDO1,RAB33A,CREM,RUBCN,GAPVD1,SMG7,DLG4,ABCC5,E2F5,RASGRP1,ATP8A1,SEC23B,GAP43,MTHFD2,KIF3A,HSF2,IL12A,MAN2A2,MITF,MKLN1,NCF2,NF1,PAK3,RETREG1,PKIA,PTHLH,ZNF821,MRAS,SH3GL3,DHX30,SORCS3,KDM4C,TROVE2,NEK4,FAM168A,TMPO,KCTD2,TP53BP2,RUNDC3B,ZFP37,SNX27,ST7,FXR1" Coexpression 15750623-Table1 Mouse Brain_Johansson05_60genes GeneSigDB 1.21E-04 1.00E+00 2.03E-03 2.01E-02 21 59 "NDRG2,OSBPL1A,SPARCL1,ATP2A2,MMD2,CALM1,CAMK2G,CHN1,CLU,CST3,CALY,TMCC2,CSDC2,GNAS,ACOT7,PLP1,QDPR,PLEKHB2,CLSTN1,NCDN,ACSBG1" Coexpression 15459216-TableA2a Human Leukemia_Haslinger04_109genes GeneSigDB 1.22E-04 1.00E+00 2.04E-03 2.02E-02 28 89 "ACTN1,APP,ARRB2,BCL7A,CD81,SLC4A7,CSF3R,ZNF804A,DMD,FGFR1,FHL1,FYN,GAB1,IQGAP2,VWA5A,MAP2,NELL2,PCDH9,PCSK5,PFKP,PTPRG,PEX5,SATB1,SEC14L1,FNBP1,TCF7,TRIM2,PSD3" Coexpression M5301 Genes up-regulated in PC3 cells (prostate cancer) after EZH2 [GeneID=2146] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.23E-04 1.00E+00 2.05E-03 2.04E-02 60 243 "C6orf89,MAP4K3,APBB2,APP,ARHGAP5,SYT6,SCARB1,KIAA1549L,MAP4K4,SLC4A8,ABI3BP,GAL3ST1,AHCTF1,CP,DOCK4,TCAF1,EARS2,MYEF2,ELMO1,CNIH3,EDIL3,TMTC1,EGFR,LPAR6,EPHA5,ST3GAL6,FHL1,CAP2,DNER,GRK4,PCLO,HAS2,HLF,GABARAPL2,NEGR1,IL6R,KCNMA1,MATN3,PRKAR1B,VPS13C,ELOVL2,SUSD4,CNTNAP3,SCN2A,SGK1,SLC12A2,CMTR2,MYO16,EPB41L3,TACR1,ZEB1,TRIM2,TPM3,RGMB,TSC1,NAV2,ZNF37BP,SSPN,DPF3,AP3B2" Coexpression 15297395-SuppTable4 Human Lymphoma_Sriuranpong04_670genes_Epithelium(N)Metaplastic/DisplasticLesions GeneSigDB 1.23E-04 1.00E+00 2.05E-03 2.04E-02 85 373 "ACHE,ADD1,AXIN2,PLA2G6,SPARCL1,SPOP,EP400,DDO,CDK10,ASCL1,NUMB,ALDH7A1,RIPK1,MPDZ,BID,CDK5R1,ARHGEF7,CACNB2,NFS1,ENTPD6,NPIPA1,B4GALT6,RAB28,FBXO7,MAP4K4,COL9A3,PLCH2,ZNF804A,RHOBTB1,DMTF1,DTNB,BSCL2,EML1,ENO2,COQ7,EPS8,FCGRT,FHL1,SEMA4D,TRIM16,GABRA3,GALC,BRD8,KIAA1958,GOLGB1,PTPRT,HSPA1L,KCNMA1,KIF5A,KLRC2,LMO1,LSS,ADAM11,MDFI,MXI1,MYO9A,NBL1,OGG1,PCDH8,PHKG1,PKD1,NXPH1,PPM1B,KLK6,RGR,ATXN2,SLIT1,SMARCD3,SNCB,MAPKBP1,SON,NACAD,GSE1,TRIM2,AKNA,SIRT1,TGFBR3,METTL3,NEIL2,TTC3,VLDLR,VSNL1,SF1,ZBTB14,FSTL5" Coexpression 16168083-Table2 Human Sarcoma_Henderson05_66genes GeneSigDB 1.24E-04 1.00E+00 2.07E-03 2.05E-02 20 55 "SPARCL1,LGR5,CDH2,CHN1,ABCG2,PDE4DIP,EMX2,ETV1,FGF1,PRUNE2,ACOT7,PDGFRA,EPB41L4B,DIRAS2,PTPRD,PTX3,ZFHX4,SHANK2,SOX11,TPM2" Coexpression 16151515-TableS4 Mouse StemCell_Forsberg05_606genes GeneSigDB 1.24E-04 1.00E+00 2.07E-03 2.06E-02 73 310 "NDRG3,NDRG2,KLHL13,LRCH2,APP,ALDH7A1,DST,SGCE,CAMK2B,LDB2,FOXN3,JAM2,ABCG2,FAM171B,TCAF1,SRGAP3,DLG3,ARRDC4,SUGP2,TNK2,TUBB3,FCGRT,FHL1,NCKAP1,SESN1,GHR,GLUL,GPD2,GRB10,GRIN2C,GUCY1A1,ICA1,AFDN,MMP16,NRBP2,MYCN,NFIA,PBX1,PCMT1,CDK18,PDE2A,DEF8,PTN,PTPN13,SLC6A15,MEG3,WLS,SEC14L1,SOX6,CLSTN1,SLC8A1,SLC12A2,SNRPN,PALLD,PDZD2,BEX1,TROVE2,SEPT8,EHBP1,DMXL2,DOCK9,OBSL1,ARHGEF12,TEX15,TEK,TGFBR3,TJP1,CBX5,BEX4,CCDC136,NDRG4,FXR1,IFT88" Coexpression M4287 Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 2 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-04 1.00E+00 2.08E-03 2.06E-02 51 198 "ASPHD1,ACHE,LRFN2,RNF182,BCHE,CAMK2B,VXN,CCNT1,CCDC151,KIF26A,NTM,CCDC3,DNAH9,DSCAM,FOXF2,CSPG5,SALL3,DIPK1C,PTPRT,MAEL,FRMD5,ZNF491,ZDHHC15,KLRC3,FGFBP3,MAPT,MOV10,NOVA1,NPR2,PAX6,PBX1,PDE1A,PURG,PRKAR1B,STK32A,RGS4,KCNIP2,LINC01354,HECW1,ANO4,LEFTY2,GALNT17,TUB,FAM155A,LINC00689,VIPR2,CRB2,PLPPR5,RGMA,NAV2,FAM181A" Coexpression M9862 Genes up-regulated in at day 0 B cell wildtype versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-04 1.00E+00 2.08E-03 2.06E-02 51 198 "ADD3,APBA2,CDC14B,LINC00847,PROM1,SGCE,CHN1,CLCN3,LETMD1,ABCG1,CSF1,JAKMIP2,USP3,FRY,DCTN4,PTK2B,PCYOX1,ZNF512,GABRG2,GALC,BRD8,KCNMB4,ADGRA3,PRUNE2,HMGCL,RBPJ,METTL21A,KCNN3,GPR155,AFF1,NAP1L2,NCF2,PBX1,PDE3B,RFX5,ZNF671,SCAF8,RCOR3,MBD5,PDZD2,SPATA7,CEP68,ZC3H4,C3orf70,PLCB1,C12orf76,CBX5,ZMYND8,CCDC14,VPS35L,MDH1B" Coexpression M3245 Genes up-regulated in comparison of naive B cells versus memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-04 1.00E+00 2.08E-03 2.06E-02 51 198 "ADARB2,LGR5,CASK,BRINP2,SYNJ1,CAMK2A,KYAT1,INA,DGKI,CHN2,NDST3,VAX2,MYEF2,MFAP3L,SNAP91,HIPK3,EFNB3,EPHB1,CORO2B,GABRB3,NCKAP1,IL1RAPL1,ADAMTS6,LINC00667,KCND3,LIFR,MEIS2,BCO1,SLCO1C1,NTRK2,PCSK1,PDZRN4,RASGRF1,RDX,CCDC82,C12orf49,SEMA6D,RIMS1,SNRPN,PALLD,TNIK,SYT11,SYN2,ZFPM2,AP4E1,SEZ6L,CHST5,RPRM,VIPR2,ZNF154,NAV3" Coexpression M8157 Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-04 1.00E+00 2.08E-03 2.06E-02 51 198 "ADARB2,NME5,BIN1,APOC1,APOC2,ATP2A2,MYOM1,BAIAP3,THSD7A,KRIT1,SLIT2,FHL5,CLIP3,SPATA2,SIDT2,PLEKHA1,VPS13B,GFAP,STMN2,SLC2A6,KLRC3,KTN1,MYH6,MYL3,NCAM2,NELL2,OPA1,PAK3,PALM,MARCH1,RAB3A,RAD17,RFX5,RNF220,CARF,CCDC92,PREX2,KDM4B,SOX11,TSPYL2,PRRC2C,MMS19,FAM208A,WWC1,FBXW11,TGFBR3,TPM3,METTL3,PORCN,PHTF2,JPH3" Coexpression M3343 Genes up-regulated in comparison of polysome bound (translated) mRNA before and 16 h after LPS (TLR4 agonist) stimulation. MSigDB C7: Immunologic Signatures (v6.0) 1.26E-04 1.00E+00 2.08E-03 2.06E-02 51 198 "ABAT,SNX30,AMPD2,DGKD,ARRB1,CAMK2G,FOXN3,CNRIP1,PREPL,HDAC4,TOX,TBC1D5,ELMO1,SACS,SGSM2,ABI2,ATP8A1,BAIAP2,EVL,HVCN1,TDRKH,GSN,AGBL5,METTL21A,LIMS1,MAN2A2,TM6SF1,STK32C,NCF2,NDUFA5,FITM2,MTMR10,PEX5,TTC13,ZYG11B,ATP8B4,RXRA,TRERF1,ZCCHC24,PDLIM2,KIAA0930,USP22,ARHGAP9,ZMAT3,ZNF106,TMEM9,NACC2,LRRC8A,TSC1,TTC3,MFF" Coexpression 20436685-ST5-2 Human Breast_Pothuri10_228genes GeneSigDB 1.27E-04 1.00E+00 2.09E-03 2.08E-02 55 218 "ADARB2,KLRC4,MTUS1,ANK1,ANK2,GAS7,NUMB,B3GALT2,RGS11,CFLAR,CALB1,KALRN,RUNX1T1,SEPT7,NRXN3,ABCG2,CNN3,TCEAL2,CHD5,DAPK1,MED24,CHRDL1,EIF1,EFEMP1,FYN,DKK3,GABRB1,MYOZ2,GATM,GNAS,PTGDR2,HLF,IFI16,IL6ST,MAOB,MAPT,MEIS2,SCG3,NAP1L3,PPP3CC,PYGM,RASGRF1,CHD9,SEC31A,INTS9,SNCA,NPAS3,ARC,MGRN1,OBSL1,TPM1,SYNPO2,UBC,VIPR2,REEP1" Coexpression M9148 Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus IKZF2 and FOXP3 [GeneID=22807;50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.32E-04 1.00E+00 2.17E-03 2.15E-02 39 140 "RBM10,ADORA3,WDR35,ABCD2,APBB2,AMER3,IGDCC4,INA,AKAP12,TENM4,CSNK1E,PDE4DIP,SLC45A1,CX3CR1,DCC,FGR,SORBS1,ATOH8,KNDC1,C2CD4C,KIF5C,MOG,MTTP,MYO7A,NTRK2,GPR88,PLXNB3,SCHIP1,UHRF1BP1,CCDC40,RPS6KA2,ZFP30,ANKRD6,LHPP,SSTR2,SYT5,LMF1,P2RY12,ZBTB16" Coexpression 18691415-Table5b Human Colon_Solmi08_36genes GeneSigDB 1.32E-04 1.00E+00 2.17E-03 2.16E-02 14 32 "FADS2,NIPBL,CDC42BPB,SGIP1,GALR1,OS9,PAH,PPP3CB,RFX3,ARMC5,RORB,ZMAT3,TP53BP2,CSDE1" Coexpression M19439 Genes up-regulated in breast cancer samples positive for ESR1 [GeneID=2099] compared to the ESR1 negative tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.33E-04 1.00E+00 2.18E-03 2.16E-02 33 112 "ABAT,KIAA1324,ALCAM,AZGP1,BMPR1B,CA12,CACNA1D,CLGN,SLC4A8,GREB1,EEF1A2,ERBB4,EVL,SYT17,GFRA1,RND1,TOX3,MAPT,MYO6,PBX1,SIDT1,ELOVL2,RET,STK32B,SYBU,IFT122,CLSTN2,SYT1,TNNT1,DNAJC12,MAP3K12,DNALI1,SEMA3B" Coexpression M357 Genes up-regulated in wildtype B cells versus BAFF-transgenic (over-express TNFSF13B [GeneID=10673]) B cells from lymph node. MSigDB C7: Immunologic Signatures (v6.0) 1.35E-04 1.00E+00 2.21E-03 2.19E-02 45 169 "B3GALT2,SYNJ1,MTMR3,CD81,DCAF8,HDAC4,PHYHIP,DAPK3,DPYSL2,FRY,STX2,SEMA4D,TMEM107,STAU2,GABRG2,SEPT9,GPD2,MAP4K5,NCKAP1L,ITPKB,JAK1,L1CAM,MATN2,SCG3,PDE4D,PDPK1,ZDHHC8,PMS2,RETREG2,GTDC1,PCMTD2,ADAL,SBF1,CASC3,FAM102A,WDR37,CCDC88A,TET1,TTBK2,ZC3H4,TGFBR3,LRRC8A,TPM3,SF1,CPNE4" Coexpression M7632 Genes down-regulated in CD8 T cells: naïve versus 2' memory. MSigDB C7: Immunologic Signatures (v6.0) 1.35E-04 1.00E+00 2.21E-03 2.19E-02 45 169 "PTCHD1,OSBPL8,OGT,MAP4K3,PDXK,ZFYVE28,ASPH,ATP2B1,CACNA1A,SPAG9,PPT2,COX4I1,PLEKHM1,GSDME,NR1D2,MBNL2,PLXNC1,PTK2B,SEMA4D,DOT1L,MPP6,GPR162,STARD3,IGF1,IL6ST,KCNJ10,STXBP5,L1CAM,TTYH2,MOV10,MX1,PTPRO,CYB561D1,FNIP1,DOCK10,SLC6A8,CPEB4,MYCBP2,NFASC,ITPRID2,ANKRD12,TPCN2,SYNE1,MICAL1,PARP11" Coexpression M2113 Genes whose expression in brain significantly and negatively correlated with the duration of all psychiatric disorders studied. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.37E-04 1.00E+00 2.24E-03 2.22E-02 40 145 "RBM10,AMPD2,MADD,ARRB2,STOML1,CLTA,COL9A3,COX4I1,CX3CR1,SEC14L5,NCALD,ECSIT,CACNG3,ACTL6B,DCTN2,NSG2,B3GAT1,GABBR1,RNPS1,OS9,GPR37,ACOT7,FXYD7,NBL1,NRGN,FTO,PMP22,MAPK3,KLK6,NDUFS7,ZMAT4,DPF2,RNH1,PUF60,DHX30,RAP1GAP2,CLASP2,ATP6V0E2,LMAN2L,NELFE" Coexpression 15845616-SuppTable3 Mouse Uterine_Jeong05_634genes GeneSigDB 1.41E-04 1.00E+00 2.30E-03 2.29E-02 105 482 "ASIC2,C1QTNF3,AMPD3,ANK1,SEMA7A,LGR5,PDXK,PTCH2,ATM,ATP1B3,MPDZ,PROM1,CALB1,SCARB1,CDO1,CLU,NIPBL,CNN3,COL9A1,CP,NCOR2,FEZ1,CTNND2,RIPOR2,MED24,ZC3H11A,FAM107B,DNM1,NR1D2,CPEB2,ABCC9,SIDT2,SH3GLB1,EIF5,ELAVL4,EIF1,F3,F5,CLVS1,ACSL4,FGF1,SEC23B,FOXF2,FOLH1,FUT9,CAB39,GAP43,ACSS1,STARD10,GATM,GFRA2,GHR,GLRB,GLUL,GPD1,RFFL,NR3C1,ACOT7,HP,IGF1,KCND2,LIFR,LIMS1,PAXBP1,MBD1,MEST,MYCN,NBL1,NCAM1,NDP,NNAT,NUCB2,ODF2,PCMT1,ENPP2,PFKFB3,SERPINE2,PIK3R1,PLTP,PSAT1,POU6F1,PPM1B,RELN,SNRK,PTH1R,PYGM,RBBP6,SCN7A,TNFRSF19,RASA3,SH3BGR,ST6GAL1,BEX1,ATP11A,TNS2,TIAM1,NACC2,TK2,BEX4,NPL,TPM4,TST,CADM1,SLAIN1,PITPNB" Coexpression M17915 "Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 24 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 159 782 "RALGAPA1,BRAP,ADORA3,HACE1,OGT,CDC42BPA,GAS7,USP37,NCOA1,NUMB,STX16,DCAF5,KSR1,SYNJ1,ARHGEF7,SCAPER,CAST,CARS,MAP7,CBS,TIGD7,CCPG1,UBE2L6,NPIPA1,RCBTB2,C4orf33,LETMD1,ENTPD4,RBM39,MICAL2,DZIP3,PNPLA8,CTH,CYBB,HDAC9,DBN1,USP3,CPEB2,SLC12A6,DPYSL2,GNE,ARRDC4,KLHL5,FSD1L,SH3GLB1,MBNL2,LINC-PINT,LINC00599,EIF5,IRAK4,PLEKHA1,ING4,EIF1,RPS6KC1,SH3YL1,PTK2B,PRAM1,GORAB,TPK1,OGA,FYN,ZNF274,ERAP1,MTHFD2,INPP5K,KIAA1841,GPT2,GOLGB1,GRB10,SPACA9,NR3C1,PSIP1,MGC16275,MIER3,HMGCL,AGFG1,LINC00667,IFI16,INPP1,ITGAV,ITPKB,JAK1,MDM4,MIA2,MYO5A,ZNF862,NASP,NEK1,ALDH1L2,NRDC,OGG1,PDE4D,SSH1,PKD1,RETREG1,SMOX,PRIMPOL,PSAT1,POLG,MINDY2,TATDN3,PTPRE,TUG1,PPP2R3C,CEP97,RAD51D,ARID4A,BSDC1,RET,RFX3,SLC25A36,ZNF671,ADAL,TCP11L1,CLIP1,SARS,ATXN1,SEC14L1,SH3BP2,SHMT2,CCDC92,SLA,RUFY2,ARHGEF40,CPEB4,GKAP1,ZCCHC24,KIF21B,UHRF1BP1L,KIF1B,CDK19,ZNF621,EPB41L3,ZSCAN29,TTBK2,ARHGEF9,SEMA4A,MLST8,TBL1X,TCF4,TCF12,AKNA,ARHGAP9,AKTIP,CBX5,TNFRSF1B,TPM4,SSBP2,UBE2H,FLRT2,VLDLR,PCBP1-AS1,WNK1,EMSY,TUBA1A,VPS35L,NUP214,NHSL1,RNF146" Coexpression M6645 Genes up-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL6 [GeneID=3469] and LPS: wildtype versus IL6 [GeneID=3469] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "APP,SULT4A1,ZNF521,CX3CR1,DGKB,RABGAP1L,RCAN1,EDNRB,SRPK3,STARD3NL,SPEG,APC2,MRVI1,CAP2,FOLR2,GABRB1,GATM,INSM2,PRUNE2,GRM8,BRINP3,KCNJ9,KCNK1,KIT,AFF1,MYCN,PDE1C,SDK2,FAT3,PRKCB,NWD1,RNASEL,RTN1,RYR1,FAM102A,ARHGEF40,NAPB,SOX1,SPP1,SPTB,SSTR2,SYT11,C3orf70,SYP,FBXW11,CRB1,FAM181B,STMN4,ADAMTS9,ST7,ST8SIA2" Coexpression M5318 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 40 h versus those from old donors treated with TSST at 40 h. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "SERPINA3,APLP1,ASPA,ADGRB3,PROM1,BMP7,BTK,REPS2,EPS15L1,DGCR9,DNAJB5,ABI3BP,CYBB,SIRPA,ELN,SYNCRIP,CGREF1,GABRA2,HIGD1B,GFER,C1QL1,GRM3,IL1RAPL1,HP,IGF1,ITIH2,LIFR,MN1,MYL3,PDE1A,PMP2,MAPK4,PTPRN,ATG16L1,SLC6A15,RFX4,TTLL7,BAALC,RPL38,PPP1R9A,ASAP3,PREX2,PCDHGA11,PHF24,TMEM151B,HIF3A,ICAM5,LILRA4,UCHL1,SLC13A3,EPM2A" Coexpression M8730 Genes up-regulated in T cells stimulated by IL2 [GeneID=3558] for 2h: STAT5 double knock-in versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "ACADM,OSBPL1A,ALAD,SPOP,APOC1,CAPN3,REPS2,CHN2,LY86,CNRIP1,CRHBP,OSBPL3,NR1D2,ABCC5,SNX29,MRO,SORBS3,EPS8,TLR7,FECH,PCYOX1,TPK1,SARAF,IQGAP2,SESN1,GGTA1P,SPIN1,STMN1,NCOA7,MEF2C,MKLN1,MXI1,NUCB1,TREM2,GDPD1,VPS13C,RPS6KA2,DGLUCY,ASRGL1,SGK1,FNDC3A,CDK5RAP3,SULF2,PLCB1,FAM208A,ACSL6,WDR7,CADM1,CCDC14,MPPE1,RNF170" Coexpression M8356 Genes down-regulated in atherosclerosis macrophages: control anti miR ctrl versus untreated. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "DPF1,NR0B1,CACNA1G,CDK5R2,KALRN,ARHGEF1,CCPG1,NIPBL,SUSD5,KIAA0513,SPATA2,MAGI2,DMPK,DSCAM,TOM1,ELAVL4,OLIG2,EXTL1,F3,FKTN,FGF12,FLT1,DKK3,MALT1,GNG4,GRIK3,GRIN2D,PTPRT,RBPJ,IL6R,ITPKB,LMO2,PCSK1,PFKFB3,FAM216A,MINDY2,RELN,RGS10,ZNF821,RASA3,MYT1L,NPAS3,DDN,VAMP1,SYT5,TCF4,DMXL2,KIAA0930,SIK3,TNFRSF1B,UBTF" Coexpression M3914 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "PLEKHG5,DSCAML1,CAPRIN2,BBS2,INA,COPB2,SOCS6,IFFO1,ZNF385A,CSF3R,HDAC9,DCT,GNE,DTNB,CELSR3,EFEMP1,NSG2,SARAF,GABRA3,INPP5K,MAN1B1,MYLK2,JAK2,KCND3,KCNK1,SYT9,IL17D,MMP17,MTTP,PROX1,RGS10,PUF60,SLC1A2,FAM81A,SMTN,SLC12A4,ZFP1,SNAP25,SSTR2,KLHL7,NSD1,ZFP91,KCTD2,SYNPO2,KLC2,ZNF23,SLC17A6,HRASLS,FZD3,SMIM8,NHSL1" Coexpression M5564 Genes up-regulated in comparison of basophils versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "CAPRIN2,CCAR2,ATM,OSGIN2,NPIPA1,DCAF8,FBXL5,NTM,SH3GLB1,RTN3,FGR,UBE2E3,SORBS1,SARAF,STAG2,GALC,IQGAP2,BRD8,MSL3,GRIA1,GRIA2,BACH2,HP,KIF5A,KIT,MBP,MEIS2,NACA,P2RY13,PCSK5,PMP22,PRKACB,PRKCB,ZCWPW1,PCMTD2,SCP2,R3HDM2,SLC4A3,ARHGEF40,BTBD7,LMBRD1,TSNAXIP1,POGZ,AGTPBP1,ZNF106,TLR4,BEX4,WIPF1,ZNF32,PRDM8,LMAN2L" Coexpression M4451 Genes up-regulated in comparison of memory IgM B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "ALK,APP,NCOA1,SLC4A4,KYAT1,CBFA2T2,SYNGR3,LY86,SLC4A7,CSF1,ERC2,CCDC144A,ZNF337,SACS,FRY,TNK2,STRADA,SCARA3,PRRC2B,SYNPO,IRF8,LINC00667,SERPINE2,PIK3CD,RETREG1,PLEC,PKIA,ZCWPW1,RASGRF1,RADX,RFX5,RGS7,ZNF532,RPS20,FAM102A,RUFY2,SLCO1A2,INTS9,KIF13A,SPP1,SYT11,CNTN2,TCF7,TMEM151B,THRA,RBFOX2,ZNF23,ATP6V0E2,MKRN3,KAT6A,ADAMTSL3" Coexpression M7382 Genes down-regulated in monocyte derived macrophages: CSF1 [GeneID=1435] versus PF4 [GeneID=5196]. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "C3orf14,KIDINS220,ANXA7,CDK13,ATP2B1,C1QC,MYRF,ZNF555,IPCEF1,UBXN2A,HDAC4,TOX,TBC1D5,DAPK1,SCRN1,KMT5B,VPS13B,PSMA3-AS1,PCYOX1,RFFL,IL6R,JAK1,MDM4,AFF1,PKN2,SLC25A48,CCDC112,ATXN7,SEC14L1,WDR47,BTBD7,ATF7IP,SP2,KDM4C,DIP2A,ANKRD12,DDHD2,IQCE,CLASP1,ARHGEF12,PUM2,AHCYL2,DCBLD1,SSBP2,EIF4ENIF1,MPPE1,MVB12B,FZD3,MARCH8,CERS6,SENP7" Coexpression M9574 Genes down-regulated in cells from peripheral lymph nodes: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "ADD2,MTMR2,GYG2,CA12,PRC1,ENTPD6,NPIPA1,CNTN1,ENTPD4,RNF14,DBI,FIS1,EML1,ENO2,EPB41L1,AMZ2,CHST15,SCARA3,CAP2,AHCYL1,RAB40B,DIDO1,JAK1,KLC1,ADAM11,MITF,NRCAM,TMOD2,SERPINE2,PLXNB1,EPB41L4B,PEX2,RAP1GAP,ZNF331,IL17RB,GALNT10,PALLD,CDK19,ANKRD28,PDLIM2,TBL1X,USP22,PCDHA3,ATP13A2,NACC2,PRMT8,TRIO,TTC3,MTCH1,VLDLR,TUBA1A" Coexpression M8408 Genes down-regulated in dendritic cells: CD8+ spleen versus brain. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "ADCY8,GRAMD1B,AGT,NCOA1,ATP2B2,BMP7,CBARP,CHN1,IQCK,AHCTF1,PPP6R2,DGKB,DCT,ZNF804A,RUSC2,C2CD2L,DTNB,EN2,EPHB1,EXTL1,EYA1,SCML2,OLFM1,GCNT2,ARFIP1,GPR12,STON1,GPR37,ITGAV,KCNA1,KCNN3,LIFR,LMO2,SMAD9,MX1,MYBPC1,NCAM1,NFIA,NPR2,ST8SIA5,PLCD1,POU3F4,MINDY2,ATXN7,SLC2A5,SLCO1A2,MAPKBP1,SOX15,RGL1,LEFTY2,SLC30A4" Coexpression M8044 Genes down-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus those activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "ADD3,LGR5,PDE8B,EIF4G3,ADAM23,RCBTB2,NDST3,MAP4K4,LY86,SRGAP3,KBTBD11,EFNA3,GPHN,TUBA1B,FYB1,GCK,GFRA1,GRB10,GRM3,WIF1,ICA1,IL6R,MSRA,MXI1,NTRK2,DDR2,TMOD2,SERPINE2,PLCL1,DIRAS2,CNNM2,GAL3ST4,EXD2,STK32B,RYR1,SCP2,ZNF821,SLC20A2,SOX2,EPB41L3,NXT2,STAU1,KANK1,TIMP4,RIMBP2,TPD52,NPL,TPM2,TUB,REEP1,ZNF195" Coexpression M4510 Genes up-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 48 h versus stimulated CD4 [GeneID=920] Th2 cells at 48 h. MSigDB C7: Immunologic Signatures (v6.0) 1.44E-04 1.00E+00 2.31E-03 2.29E-02 51 199 "AGT,LDLRAD4,DGKI,SOCS6,CHRNA4,CHRNB2,DNAJB5,CDC42BPB,SIPA1L1,CTNND2,DLG2,RCAN1,DTNB,OLIG2,NCALD,CEND1,CD320,SORBS1,RASL10A,GABRG2,SYT17,GCNT2,LILRA2,SPACA9,IL1RAPL1,BACH2,TUBB2B,LSAMP,MOBP,NPY,NRCAM,PRKCZ,PROX1,PTPRO,RAP1GAP,TCP11L1,RTN1,MRAS,SGK1,PREX2,SLC11A1,SLC15A2,KIF21B,INKA2,STXBP1,ANKRD28,TLL2,NR2E1,CDK20,TRPS1,PMEPA1" Coexpression 17676974-TableS1 Mouse StemCell_Chambers07_1667genes GeneSigDB 1.50E-04 1.00E+00 2.40E-03 2.39E-02 238 1236 "ADD3,KLHL13,SPOP,ALCAM,AMPD3,API5,APP,ARHGAP5,ASPA,ASPH,DDX3Y,ATP1A1,ATP1B3,ATP2A2,BACH1,CFLAR,BTK,OSGIN2,DDR1,CAMK2D,CANX,CCNH,CD38,ENTPD2,CD81,SEPT7,CDC42,CFL2,COPB2,RCBTB2,SOCS6,CHN2,JAM2,CLCN3,CLU,CLTB,CLTC,FADS2,LY86,CNN3,CNTN1,BAG4,PREPL,CREM,ANKRD44,CSF1R,CSNK1E,PNPLA8,PUM1,TOX,TM9SF4,DBI,PITPNC1,ARMCX2,YTHDC1,DDX46,NR1D2,SLC12A6,ABI1,PDCD6IP,RCAN1,DYRK1A,ABCC5,E2F5,E2F6,HIPK3,RBM12,YAF2,PLXNC1,GOLGA7,ASB3,EIF4G2,SORBS3,EIF5,PLEKHA1,STARD3NL,EPS8,RTN3,WAC,ACSL4,PTK2B,TAOK3,ATP8A1,ST3GAL6,FECH,PRKAG2,FHL1,SEC23B,NBEA,SORBS1,PDLIM5,TRIM16,NPTN,ATP2C1,KHDRBS3,STAU2,OGA,FYB1,STAG2,CAB39,AHCYL1,ZMYND11,ERAP1,GCNT2,GHR,TCERG1,SPIN1,FERMT2,PCLO,GRB10,KIF3A,GUCY1B1,MAP4K5,HLF,ELOVL5,HMGB1,GABARAPL2,SYNPO,HMGCR,HNRNPK,HP,AGFG1,HSP90AA1,SMAP1,MSL1,RBPJ,IL6ST,ITGAV,JAK1,KIT,IPO5,LAMP2,VWA5A,MEF2C,MEIS1,MEIS2,MIA2,MYCN,MYO6,HNRNPM,NAP1L1,NCAM1,NFE2L2,NFYA,NRGN,NUCB1,PBX1,PDE4B,OLA1,CDK14,SERPINE2,SERPINI1,PIK3R1,PKM,PMP22,STRN3,PSAT1,ING3,SPATA6,PPM1B,PPP2R5C,EPDR1,GDPD1,PTCH1,MTMR10,PTN,PLEKHB2,RAP1GDS1,OXR1,RBBP6,RBBP8,RDX,SLC6A15,NUDT11,FBXW7,ZC3H14,PTGR2,WLS,SELL,SFPQ,TRA2B,HSPA4L,SCAF8,DZIP1,SLC12A2,SLC14A1,ELMO2,CPEB4,SMARCE1,CMTR2,LMBRD1,USP33,FNBP1,UHRF1BP1L,TEX2,KIF1B,SRPK2,TAB2,SS18,TAC1,FBXW11,TBL1X,TRIM2,DOCK9,ARHGEF12,PUM2,TEK,SLC44A1,TIAM1,TIE1,NACC2,TLR4,LRRC8A,TPD52,TPM3,TPM4,TRPC1,RUSC1,TSN,TTC3,CADM1,SLAIN1,PITPNB,MTCH1,VLDLR,TBC1D15,SF1,ZFAND5,WNK1,CSDE1,RNF103,NAV2,CAB39L,GOPC,FZD3,RTN4,PHTF2,FXR1" Coexpression M2580 Genes consistently down-regulated in mature mammary luminal cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.51E-04 1.00E+00 2.42E-03 2.41E-02 30 99 "AXIN2,SPARCL1,LTBP4,CAMK2D,FOXN3,B4GALT6,MAP4K4,ZNF521,TIAM2,DPYSL2,FAM13A,EGFR,EPB41L2,RASL12,C2orf88,SORBS1,ITPKB,MEIS2,NTRK2,IRX1,LAMA1,SLC6A15,RASA3,SLC1A3,PDZRN3,SOX10,STAC2,TGFBR3,HEY2,FAM181B" Coexpression M2692 Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of ATM [Gene ID=472] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.61E-04 1.00E+00 2.47E-03 2.45E-02 40 146 "APBA2,NUMB,MYOM1,BCHE,CHGB,SLC22A6,CNTFR,COL9A3,AKAP5,CSF3R,TIAM2,ECM2,ABCA8,PTK2B,FCGR1A,FLT1,GPR162,GJB1,GRIK1,SOX21,HPR,KCNJ4,N6AMT1,P2RY1,PHKG1,EPN1,PLTP,RAB3A,RET,RGS12,RPE65,ASIC4,SLC6A1,SNCB,LHPP,SYN1,ICAM5,VAV2,BEST1,NDRG4" Coexpression 14695196-Table2 Human Colon_Mariadason03_420genes GeneSigDB 1.61E-04 1.00E+00 2.47E-03 2.45E-02 71 302 "ACLY,KIDINS220,AMPD3,CDC42BPA,EP400,APC,GPAM,MIER1,ARHGAP5,CHID1,FUBP1,TPP1,CNN3,CLOCK,TRIM69,GREB1,SEC14L5,DAPK1,SACS,KBTBD11,TSPAN5,HIPK3,HEYL,EGR3,LPAR6,KCTD3,EIF5,RTN3,TBC1D16,SCARA3,FOXO3,FOLH1,SPIN1,RAB40B,PSIP1,ADAMTS6,SHISAL1,LIFR,MRPL42,NAP1L1,NF1,NFYA,NNAT,SLC11A2,NUCB2,ABCB1,APTX,RDX,PBRM1,ZNF532,TMLHE,SFPQ,SEC31A,SMTN,ZHX3,GLT8D1,ADHFE1,TBCEL,ARHGEF12,AP4E1,GZF1,ACTR6,PDSS1,DCBLD1,TTC3,UBE3A,CLIP2,ZNF19,POLR3H,SMARCAD1,EVI5" Coexpression 17597811-SuppTable5 Human Leukemia_Mullighan07_744genes GeneSigDB 1.61E-04 1.00E+00 2.47E-03 2.45E-02 126 599 "ABR,ADRB2,AP1B1,OSBPL8,AK2,MRTFA,BEGAIN,BIN1,GAS7,APP,AQP4,DYNLL1,MTMR9,BID,RAB29,WASF1,BAIAP3,CA4,CALM1,HIP1R,RUNX1T1,PPT2,TPP1,CLTB,NIPBL,HOMER3,CHD1L,CLIP3,CSF2RA,IPCEF1,SIPA1L1,PPP1R16B,ST18,RASSF2,DAPK1,SIRPA,ELMO1,DNM2,RCAN1,EEF1D,EGR3,PLXNC1,SIRPB1,ABCA8,PTK2B,DLC1,FCGR1A,FDFT1,SEC23B,STAMBP,RASL10A,ATP2C1,ZNF274,GGT5,MALT1,BRD8,HPGDS,GLYR1,LILRB4,LILRA1,LILRA2,HLF,IRF8,IL6R,ITGA7,ITGAV,JAK1,KLC1,MBNL1,MEIS1,CD200,FXYD6,NBL1,NINJ2,NOVA2,OGG1,OPRL1,CYTL1,OLA1,ABCB1,SERPINE2,SNX10,PKM,PILRA,TNPO2,NDUFS7,SIDT1,PTAFR,RIPOR1,RBBP8,GTDC1,NUDT11,BAALC,ATP8B4,STK32B,RXRA,ASAP3,SLA,ARHGEF40,SLC12A4,SLC15A2,SOX11,ZSWIM8,CAND2,NXT2,MCF2L,TAL1,IQCE,KIAA0930,TIE1,TK2,TPD52,TRH,ZMYND8,TTC3,DNAJC12,PITPNB,MICAL1,LAT2,SLC13A3,SH3GLB2,TRIM16L,MPPE1,MVB12B,JMJD1C,NLRP3" Coexpression M1535 "Down-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls" MSigDB C2: CGP Curated Gene Sets (v6.0) 1.61E-04 1.00E+00 2.47E-03 2.45E-02 16 40 "ACHE,ATP2A2,CAMK2G,CANX,MAGED1,CS,DLG4,DNM1,VTI1B,GRIA1,PRKACB,SARS,DHX30,SYT1,UBC,VSNL1" Coexpression 17952125-Table1a Human Pancreas_Harada08_34genes GeneSigDB 1.63E-04 1.00E+00 2.47E-03 2.45E-02 11 22 "BRINP2,ASTN1,PDE4DIP,SMG7,EGFR,ERBB2,HNF4G,DDR2,NMNAT2,TNR,CPNE4" Coexpression M9270 Genes that best predicted acute myeloid leukemia (AML) with the 11q23 rearrangements. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.63E-04 1.00E+00 2.47E-03 2.45E-02 11 22 "C3orf14,TKTL1,APOC2,ITGA7,PENK,C1orf54,RET,NXT2,KCNE5,CADM1,LAMP5" Coexpression M3100 Genes up-regulated in comparison of macrophages treated with control (hIgG1) versus those treated with TNFRSF6B [GeneID=8771]. MSigDB C7: Immunologic Signatures (v6.0) 1.64E-04 1.00E+00 2.47E-03 2.45E-02 50 195 "ADORA3,AP2A2,AP1B1,KSR1,ASIC3,TPP1,HOMER3,CSF2RA,DAPK1,ZC3H11A,RHOBTB1,SRGAP3,HS3ST2,ABCC5,WDPCP,SEMA4D,FOLR2,CAMKK2,CBX1,KCNMB4,CROCCP2,KAT7,USP51,SMAP1,IRF8,INPP5B,LSS,COMMD5,LYRM9,FXYD6,P2RX7,PLEC,SPATA6,SIDT1,PEX5,RIPOR1,PID1,PLEKHB2,LRRK2,ARHGAP26,IQSEC2,ERBIN,ARHGAP9,NR2C2,TTTY15,NPDC1,ZFAND5,MPPE1,MARCH8,RNF146" Coexpression M3209 Genes up-regulated in comparison of immature NK cells versus intermediate mature NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "FAM43B,PKP4,APBB2,GPAM,NOL4,KIF1A,TTC9B,CA4,CCKBR,NEURL1,DLGAP1,CLCN3,FHL5,ARHGEF10,TCAF1,CDON,TMEM132E,FGR,PSD2,TACC2,AK8,NSG2,TUBA8,SRCAP,GFAP,DBF4,TMEM179,KCND3,CLVS2,KIT,MAN2A2,MBP,NEFH,NNAT,NPPA,PENK,TMIE,PLCD1,SIDT1,SGSM1,HOGA1,SOX6,RADIL,LGI3,MESP1,SEPT8,KAZN,MCF2L,GPR161,UBE2H,RGMA" Coexpression M3438 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "CLK4,APBB1,APC,ARNTL,ARSE,ST3GAL5,ARHGEF7,CA8,CAPN3,CD38,AKAP7,PLCH2,SIRPA,PLEKHM1,KBTBD11,FRY,EGR3,TENM1,GPR153,RAPGEF6,ARPP21,GPR19,ITPKB,MITF,PDE4D,PLCL1,POU3F4,RAD52,ATG16L1,RGR,RIC8B,PCMTD2,MAP6D1,SGK1,FAM102A,ST6GAL1,SLC6A7,SLC12A4,KDM4B,ACSBG1,ASTN2,DNMBP,WWC1,SYNE1,TIAM1,CABIN1,RPRM,MPPE1,MVB12B,C12orf4,IFT88" Coexpression M5915 Genes encoding components of apical junction complex. MSigDB H: Hallmark Gene Sets (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ACTN1,ACTN2,ADRA1B,AMH,SHROOM2,ATP1A3,CADM3,ADAM23,ADAM15,SGCE,CALB2,CD86,CDH8,TAOK2,SLIT2,NRXN2,ARHGEF6,CNTN1,COL9A1,NECTIN3,VCAN,SDC3,CTNND1,SIRPA,EGFR,SORBS3,CERCAM,EPB41L2,SPEG,BAIAP2,EVL,FLNC,FYB1,TMEM8B,NEGR1,KCNH2,LAYN,NF1,CLDN11,NLGN3,PKD1,PPP2R2C,PTK2,NFASC,TJP1,ICAM5,TRO,TSC1,VAV2,SLC30A3,CADM2" Coexpression M7491 Genes up-regulated in SELL dim [GeneID=6402] NK cells: NCAM1+ [GeneID=4684] versus NCAM1- [GeneID=4684]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ABHD6,AS3MT,ZNF608,PRX,MYOM1,RAB29,CACNB2,CAMK2G,CERS5,ABCG1,CSNK1E,APPL1,HDAC9,GPRASP1,RIPOR2,RASSF2,DOCK2,LPAR6,SORBS3,CALCRL,RASGRP2,RCSD1,EXTL2,ALDH1L1,GHR,IL11RA,INSYN2,SMAD1,MEIS1,SESN3,NCF2,OCRL,CDK18,PKM,RASGEF1B,C1orf54,PEAR1,CEP68,KAZN,TLR4,TPD52,NPL,TRPS1,VAV1,ZNF184,PARP11,AMN1,CERS6,VANGL2,IFT88,SPATA13" Coexpression M5673 Genes up-regulated in comparison of TconvLN versus TregLN (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADCY6,RNF150,AP2A2,KCTD16,PPFIA4,APP,CDK10,FOXK1,CARS,MAP7,CNN3,CREB5,AKAP12,TRIM69,DCC,HP1BP3,GUCD1,NYAP1,RASGRP2,GPD2,RAPGEF4,GSN,HPS5,GATD1,AQP11,MBP,MIA2,DDX25,NFE2L2,SETD4,PDE3B,TMIE,SH3KBP1,ATP8B4,CLIP1,RYR1,SATB1,RASA3,SOX5,ZHX3,SPP1,SEMA4A,SYNE1,PSD3,VWCE,TGFBR3,PIK3R5,RGMB,SLC30A4,CERS6,KLHDC1" Coexpression M7420 Genes up-regulated in mature neuron cell line: control versus interferon alpha (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "SLITRK1,TMCC3,ZNF608,TBC1D14,GOLGA7B,NRP2,MTMR3,CD86,LGI1,CTNND1,CYBB,RIMS3,SPOCK2,NTM,DLG4,TMEM164,GABBR1,INPP5K,GCK,TMEM25,IGSF1,KCND2,KCNH2,ADAM11,LRP1B,PPM1L,ZDHHC8,SSH1,PIK3R1,MDGA2,PTPN13,RAB3A,FAT4,RNASEL,WLS,IL17RB,SGK1,SLC14A1,C3orf70,SYP,SYT4,AHCYL2,TIAM1,RIMBP2,TNS1,CA10,PRDM2,PPP1R3F,ITM2C,PIANP,NETO1" Coexpression M8054 Genes down-regulated in macrophages: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "RALGAPA1,TMCC3,DGKZ,PDXK,DOCK11,SYNJ1,FMNL3,REPS2,LY86,TBPL1,CST3,DZIP3,APPL1,HDAC9,GAPVD1,PLEKHM1,WDR20,DMTF1,SNX29,CALCRL,PLEKHO1,EXTL2,EYA1,FAM198B,PTK2B,PDLIM5,RAPGEF6,GPR19,GPR34,ARHGAP19,LYRM9,PLEC,SH3KBP1,MTMR10,PTPRO,OXR1,ACER3,CPEB3,SLA,SULF2,DNAJC9,TCF12,ITGB3BP,KCTD2,SMUG1,RUNDC3B,AMOT,ZFAND5,WNK1,ITM2C,JMJD1C" Coexpression M4444 Genes up-regulated in comparison of memory IgG IgA B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ARID1A,ADCY6,PDE8B,MARCH3,ZSCAN18,ATM,BAIAP3,DDR1,DGKI,NRXN1,LY86,CSF2RA,RIPOR2,TBC1D5,FRY,EBI3,RGS17,RASGRP2,CORO2B,CAP2,DLL3,OGA,FYN,GABBR1,CHL1,GATM,GUCY1A1,SYNPO,IRF8,KPNA5,MAOB,NEUROD1,NOS1,NTRK2,PCDH9,PDE4D,PIK3CD,SNX10,MARCH1,TRIM68,RET,ZNF532,SYBU,SPTAN1,LHPP,SATB2,TTTY15,ATP6V0E2,PRDM2,KAT6A,NLRP3" Coexpression M3850 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "TMEFF1,ARHGDIA,MARK4,LRBA,PPT2,TPP1,MAP4K4,CNR1,COL9A3,BAG4,NCOR1,MYADM,MAML1,DPYSL2,PHC2,EIF4G1,OLIG2,EPB41L1,FGFR3,CAMSAP1,GALC,GAP43,INPP5K,GLUL,GPT2,FRMD5,MBD1,AFF1,GIT1,NPTX1,GPR85,TMOD2,GDAP1L1,ZNF426,RC3H2,TNPO2,UHRF1BP1,DPF2,RPS6KA2,ATXN2,MYO18A,PEX26,FAM214B,MLC1,RHBDL3,EHBP1,KIAA0930,ZEB1,TRPC1,MKRN3,NLRP3" Coexpression M5834 Genes down-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "APP,ATP2A2,CANX,ADGRG1,ZFP28,HINFP,ABCG1,CSF1,NCAN,SPOCK2,EFNB3,PLEKHA1,EFS,TLR7,POLR1B,FHL1,CHL1,GNAO1,GPM6B,PCLO,SCRG1,DOCK7,SMAD1,MAP2,MITF,MYO6,NAP1L2,NEFH,NEUROD1,NKX2-2,CLDN11,ENPP2,MTRF1L,MAGEL2,TUG1,RGS10,WLS,SCN7A,ZNF821,SLC12A2,SPP1,SYT1,TBX15,TCF4,TRPC1,SSBP2,CADM1,CELF4,EVI5,KCNAB1,NELFE" Coexpression M7478 Genes up-regulated in periperal blood monocytes (PBMC) from kidney transplant recipients: tolerant versus immunosuppressive therapy. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "SYN3,OSBPL6,SYT13,DDO,MARCH3,DNAH17,SYT6,MAP7,KRIT1,CBFA2T2,KMT2C,NMT2,SIPA1L1,CNTNAP2,TMEM170A,PABPC5,PITPNC1,ELMSAN1,SH3YL1,CAMSAP1,FHL1,CAP2,FOXO3,SORBS1,CSPG5,GAB1,NKX6-2,GFRA2,KIAA1958,GRM3,ZBTB45,USP54,SMAD9,SHC3,LYRM9,NAP1L3,NUCB1,FAM184A,BSDC1,RGS12,RNASE1,NLGN1,URGCP,LHPP,STXBP1,PCDHB6,GPR161,PARD3,TSC1,CADM1,PLSCR4" Coexpression M8532 Genes up-regulated in macrophages: resting differentiated versus MYC [GeneID=4609] inhibited. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADRB2,TXNDC16,ALCAM,BTK,HIP1R,LDB2,CD38,CD81,CPNE6,CNN3,SLC32A1,MYADM,EBF1,EBI3,EPB41L2,RASGRP2,FCGRT,GABRA3,GAD1,NKX6-2,GCK,C1QL1,GRIN2D,GSN,HSD17B1,IRF8,LAMP2,MEF2C,MYO5A,MYO7A,NAP1L1,PLTP,PXK,ZDHHC14,ZNF532,RYR1,SELL,ITSN1,DNAJC9,SYPL1,TCF4,KIAA0930,NSD1,DDHD1,LRRC8A,TPD52,C9orf85,LAT2,SLC30A4,URM1,PHTF2" Coexpression M9692 Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 60h. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "NR0B1,ALCAM,PTCH2,CFLAR,CA12,CCKBR,P2RX6,CLGN,ADGRG1,B4GALT6,NMT2,WDR20,CASP8AP2,RCAN1,COPS4,ELAVL4,PTK2B,SPECC1,SARAF,HBS1L,GATM,GFAP,PPARGC1A,LYVE1,GLDC,GNAO1,CNTRL,FAAP20,KHK,MAP6,MIA2,MYL3,MYO5A,NAP1L2,NDP,NF1,MAGEL2,PPP3CA,PTPRE,AP1AR,SARS,ATXN2,MYT1L,KDM3A,FCHO1,NEK4,ANKRD28,ROBO3,AKTIP,MKRN3,ZFAND5" Coexpression M7335 Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by stimulation with T cell membranes. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "KLHL32,PNMA8B,RNF150,KLHL13,KIAA1324,TXNDC16,PHYHD1,AQP4,ASPH,CACNA2D1,REPS2,ARHGEF6,COL4A5,AKAP12,CSF1R,ATRNL1,CTH,ABCC9,E2F6,EDNRB,RCAN2,EFEMP1,ST3GAL6,SUCO,HBS1L,FERMT2,GP1BB,GPR34,GRB10,ARHGAP19,BRINP3,MAN2A2,MRPL42,NFIA,PDE2A,CYTL1,ZFYVE21,PKIA,NDUFS7,EML5,S100B,ST6GAL1,TGFBR3,ZNF346,RFTN2,TTC3,UBE2H,UCHL1,VLDLR,EMSY,HRASLS" Coexpression M7207 Genes up-regulated in tumors established by injecting MC38 cells (colon cancer): control versus CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADCY6,ADD1,SORCS2,CARNS1,PPFIA4,TNRC6C,MADD,CAMK2G,RHBDL1,ENTPD6,RCBTB2,KMT2C,COL9A3,VCAN,ECE2,GUCD1,SEC16A,DNM2,TOM1,ABCC9,SIDT2,EIF4G1,RASGRP2,RCSD1,ACTL6B,NOP56,ZNF605,GAA,SESN1,ADAM28,GGT5,HSD17B1,KCNMA1,GIT1,PTOV1,PLEC,FEZF2,STK32B,WLS,SELL,GALNT10,RASA3,SLC6A8,SNCA,PBLD,KAZN,PCDHB7,NACC2,TTC3,SLC35A4,ZNF23" Coexpression M293 Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from: mesenteric lymph nodes (mLN) versus spleen. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "GPRASP2,MRTFA,ALDH7A1,BCL2L2,CAMK2G,KYAT1,CBFA2T2,RCBTB2,TPP1,MAGED1,ARHGEF4,DNAJC6,SLC12A6,RASA4,CALCRL,HSPA12B,REEP2,ABCA8,RPS6KC1,PPP1R1B,FER,GTF2IRD2,GATM,NCKAP1L,RBPJ,DOCK7,JAK1,MBP,RETREG1,MAPK7,DEF8,ARID4A,RNF220,KLHDC8A,BTBD3,RUFY2,ATF7IP,CLUAP1,MYCBP2,GSE1,KLHL7,DNAJC9,TACC1,DNMBP,ARHGAP9,METTL3,TTC3,SGK3,VIPR2,KCNK12,PLD4" Coexpression M5970 Genes up-regulated in liver: IFNG [GeneID=3458] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "PLEKHG5,SNX30,OGT,TNRC6C,STX16,BCL2L2,CFLAR,CDK5R1,PRMT9,CACNA1B,MAP7,CERS5,NRXN2,HECTD1,NIPBL,GIT2,SRGAP3,HIPK3,HEYL,KMT5B,ING4,KATNAL1,EZH1,ST3GAL6,STAG2,GPR19,BACH2,JAK1,MBD1,NCF2,NUMA1,PDE3B,PDE1B,ANLN,MINDY2,TUG1,CEP97,CCDC82,PCMTD2,SUPT20H,RAB3GAP1,ZKSCAN3,USP33,SS18,TTBK2,GSE1,SLAIN1,RICTOR,ZFAND5,JMJD1C,RNF146" Coexpression M8030 Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IFNG and TNF [GeneID=3458;7124]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ACTN1,ADD3,MTUS1,OSBPL8,STX16,MYOM2,RAB33A,DZIP3,ZFYVE16,MAML1,SPOCK2,PITPNC1,CEP170,TENM1,VPS13B,SH3YL1,SEC24B,SEMA4D,NPTN,FYN,CAB39,ZNF276,BTN2A1,BACH2,HSPA1L,IL6R,IL6ST,JAK1,MAN2A2,MARK3,NELL2,PFKFB3,ABCB1,ING3,PPM1B,LRRN3,PPP2R5E,PTK2,PCMTD2,GALNT10,SUPT20H,DOCK10,SLA,RAB3GAP1,ATF7IP,NAXD,KDM4B,ZSWIM8,ERBIN,TIAM1,MICAL1" Coexpression M6943 Genes down-regulated in B lymphocytes: PL2-3 (Chromatin IC) versus anti IgM and CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "NDRG2,APLP1,MIER1,BCL2L2,GPR146,MTMR3,CAST,SPAG9,TMEM184B,HECTD1,LETMD1,SLC4A7,PITPNC1,RABGAP1L,RASGRP1,YAF2,SH3GLB1,C3orf18,NRN1,ACSL4,TMEM107,FYN,GALC,SEPT9,GRIN1,AFF1,AFDN,MXI1,PC,SMOX,DRAM2,POU6F1,CASTOR1,RAD52,RAP1GDS1,REV3L,FNIP1,DOCK10,SMARCE1,KDM3A,TEX2,CAMSAP2,AGTPBP1,USP22,HEY1,TP53BP2,TPD52,C9orf85,TMEM237,WNK1,PRDM2" Coexpression M8357 Genes up-regulated in atherosclerosis macrophages: anti miR-33 versus anti miR. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ANK2,APOC1,BRINP2,EIF4G3,CLDN10,MYOM2,SEPT7,CHM,CRHBP,TENM4,PHYHIP,ZNF804A,ECM2,EDIL3,EFNA3,EN2,PNMA2,C1QL1,RUNDC3A,RAB30,GP1BB,GPR37,PCLO,GRM8,BTN2A1,GUCY1A2,KCNJ9,LMO1,PAH,LRRN3,MAPK4,PTPN13,PTPRE,PTPRZ1,PLEKHB2,IQSEC3,RORB,SELL,SLA,SLC1A3,SLC6A1,FAIM2,ZNF415,FNBP1,SPP1,UNC5B,ARHGEF12,TP53BP2,FLRT2,CLIP2,WNK1" Coexpression M7155 Genes down-regulated in CD4 [GeneID=920] T cells versus follicular helper CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "NDRG3,USP28,DGKZ,APP,SFMBT2,ARRB2,RGS11,CAST,RCBTB2,CRMP1,ARHGEF4,DNAJC6,KBTBD11,DPYSL2,CALCRL,MEX3B,SDCBP2,ERAP1,MTHFD2,SEPT9,KCNMB4,GPR34,ZBTB45,ZDHHC15,RBPJ,IL6R,IL6ST,INPP1,INPP5B,SLC35G1,STXBP5,L1CAM,FGFBP3,P2RX7,PDE3B,TMIE,GPSM2,SMOX,SLC25A23,SPATA6,PRKCZ,OXR1,RNASEL,ATP8B4,RCOR3,STX1A,RHBDL3,RUNDC3B,MEIS3,CERS6,ADAMTS10" Coexpression M6269 Genes up-regulated in medullary thymic epithelial cells (mTEC) with AIRE [GeneID=326] knockout: CD80 [GeneID=941] high versus low. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ABR,NCKAP5,SEMA7A,B3GALT2,SGCE,CH25H,SRSF11,ASIC3,RAB3C,RAB33A,SLC4A7,MAGED1,VCAN,MYADM,BRINP1,NRN1,ABCA8,PPP1R1B,OLFM1,SUCO,ATP13A4,AKAP3,CGREF1,FYB1,JPH4,DNER,GK,PLCD4,IRAK3,SCIN,IL12A,KCNF1,CD200,MXI1,PENK,PLTP,PILRA,ROGDI,ENOX1,ATP8B4,SLA,SLC1A2,SLC4A3,SNCA,SOX5,SPX,TIAM1,ZFP91,SYNC,TMEM178A,PCBP4" Coexpression M4312 Genes down-regulated in comparison of TregCD103-Klrg1 versus TconvLP (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "DACT3,ALDH7A1,BLM,FAM171B,MICAL2,CSNK1E,PLCXD3,RASSF2,PITPNC1,EDNRA,LPAR6,RASGRP2,EFS,EZH1,ACSS1,GPD2,IL6R,DIPK1A,CDH20,MGAT3,SESN3,MYO6,NFE2L2,NME4,OLR1,ABCB1,TMIE,ANLN,SMOX,LRP12,PPP3CB,CCDC82,ATP8B4,DZIP1,ANKRD6,RAB3GAP1,MYCBP2,RAP1GAP2,KLHL7,SEMA4A,ANO4,CUX2,PHF24,NACC2,SMUG1,TTC3,SGK3,VSNL1,CERS6,RNF170,KLHDC1" Coexpression M4334 Genes down-regulated in comparison of DEC-Pept Convert versus DEC-Pept CD25- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "AXIN2,CNTNAP1,CHRD,ATP2B2,CDH2,RAB33A,ANKRD35,PNPLA8,DNAJC6,AASDH,IRAK4,ADGRV1,HPCAL4,C2orf88,NSG2,AP4B1,SYT17,GLDC,STMN2,IRAK3,TOX2,HSD17B1,SMAP1,INPP1,KIT,CAMK2N2,MOG,CTNNA3,HCN1,PDE3B,ENPP2,SIDT1,ANKHD1,CEP97,ATP8B4,PRR5L,ABLIM3,CCDC88A,PDZRN3,RAP1GAP2,RGL1,SEMA4A,PJA1,TEX15,ARL10,CDK20,FAM181B,NSD2,SLC26A10,ZNF189,LAMP5" Coexpression M4341 Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "SEMA7A,CCDC146,EPB41L5,ARRB2,CDH2,IGLON5,AKAP5,CRY2,CRYM,LRIG1,ARHGEF10,HDAC4,PHYHIP,ARMCX2,DNAJC6,CERCAM,RAB9B,EXTL1,F8,FCGR1A,AKAP3,ZNF512,CHL1,SRCAP,HTATSF1,GUCY1B1,TMEM179,CDH20,KCNH2,AFF1,MTR,ZNF827,PKD1,PILRA,DRAM2,PPP2R2C,MAPK12,SELL,FAM102A,MAGI3,SLC6A7,LARP4,ARHGEF9,MCF2L,WWC1,TMEM151B,FRYL,NTSR2,ZFP37,STOX2,NETO1" Coexpression M8298 Genes up-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADD3,PLA2G6,AMT,CDC42BPA,DGKZ,STX16,SPAG9,FOXN3,PPT2,CREM,RBM39,PPP6R2,TOX,SGSM2,DNAJB6,SORBS3,TENM1,SH3YL1,ST3GAL6,FCGRT,FGFR1,SARAF,GAD2,OS9,KAT7,IL11RA,ITPKB,MXI1,NUCB2,OCRL,PAX6,PDE4B,PLCD1,MINDY2,SNRK,RGS10,RPL38,RPS20,RASA3,SGK1,CLSTN1,FAM168A,SYNE2,MCF2L,TCF7,RALYL,TPM2,NR2C2,TRIO,TSN,TUBA1A" Coexpression M3070 Genes down-regulated in comparison of effector CD8 T cells KRLG1 Int [GeneID=10219] vs those with KRLG1 Hi. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "CSMD2,ESYT2,BBOX1,APAF1,SLC16A4,MS4A7,LY86,ARHGEF6,SMARCAL1,CSF1R,CSF3R,OLIG1,RASGRP1,PLXNC1,VPS13B,EPB41L2,EXTL1,FYN,NCKAP1,IQGAP2,ARFIP1,DBF4,CECR2,IGSF21,FRMD3,ZDHHC15,C2orf72,DIPK1A,NCF2,NRDC,OPRL1,ETFRF1,CYTL1,ANLN,SNX10,MAPK9,SYTL2,MDGA2,FAM184A,ZYG11B,ATP8B4,KIF16B,SSTR2,WDR7,CBX5,HEPACAM,PLEKHH2,CCDC136,WNK1,CAMK1G,SLC4A10" Coexpression M6715 Genes down-regulated in endothelial cells: untreated versus IFNG [GeneID=3459] and B. burgdoferi. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "SORCS1,VAT1L,MARK4,KIF1A,CARMIL3,CABP7,C4orf33,CRYBB1,CLIP3,FAM131B,KIF26A,SPOCK2,TIAM2,CHRDL1,DLG3,DNM1,PDCD6IP,LRRC17,SDCBP2,PHYHIPL,GAA,SRRM4,STARD10,GPR75,PCSK1N,FAM222A,HNF4G,LRRCC1,LMO1,MYO9A,ZDHHC22,PDE1C,NECAB2,PRODH,PRPH,MTMR10,RALGDS,RGS7,RXRA,FRMPD1,SLC2A5,SPHKAP,SOX3,PEG10,SEPT3,CNTN2,TMEFF2,CLEC2L,PLPPR2,ZFP41,NETO1" Coexpression M5494 Genes up-regulated in comparison of macrophages versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ASPHD1,DDO,PDXK,NUMB,DST,CD86,CHN2,CREM,MICAL2,IPCEF1,ERC2,DBI,HS3ST2,DPYSL2,RCAN1,TAOK3,DLC1,FHL1,FOXO3,FLT1,GABRA3,AHCYL1,GCNT2,GK,SPIN1,ADGRA3,GPD1,GPD2,EML4,CIT,ACOT7,HP,RBPJ,MT3,MYO6,OCRL,PDE4A,DIRAS2,SYTL2,PTPN13,ZMAT4,TCP11L1,SCG5,SLC11A1,SLC22A4,ITPRID2,CHST8,TLR4,BEX4,PLPPR2,NLRP3" Coexpression M6477 Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS like antigen from O. planktothrix (3h). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ZNF608,MTUS1,PI16,APOC1,MARCH3,STX16,N4BP2L1,ADAM23,FOXN3,KMT2C,NIPBL,SLC25A27,ENTPD4,TIAM2,FAM107B,KBTBD11,SLC12A6,IGSF6,ZMAT1,GCNT2,TUBGCP4,GFRA2,ELOVL5,IL6R,INSM1,KCNJ16,L1CAM,PAXBP1,BLOC1S2,ADAM22,PBX1,PRKCB,MAPK8,ROGDI,RGS12,PRR5L,KCNIP3,RYR3,SEMA6D,SCN3A,RASA3,ST8SIA1,ATF7IP,SAMSN1,FGD4,VAMP1,AKNA,PUM2,NR2C2,ZBTB16,JMJD1C" Coexpression M5737 Genes up-regulated in comparison of lymph node regulatory T cells versus thymus regulatory T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "KDM5D,TBC1D14,ARRB1,DDX3Y,MAP7,MTMR7,CD86,FOXN3,LRIG1,IPCEF1,ELMSAN1,ARNT2,DMD,NR1D2,PLXNC1,ETV1,FGF13,TMEM175,HVCN1,GPM6B,GUCY1B1,ATG4C,IRAK3,SYNPO,KIF5C,MAT2A,NFIA,PDE2A,ABCB1,PLCL1,POU6F1,OXR1,TRIM68,RPS6KA2,FOXRED2,PEAR1,GALNT10,SUPT20H,SLC15A2,ATF7IP,KIF13A,SEPT8,KIAA0930,AKNA,ARHGEF12,KCTD2,TPD52,RUNDC3B,MFF,WIPF2,TTC7A" Coexpression M5049 Genes up-regulated in comparison of splenic secondary CD8 effector T cells at day 8 post-acute infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "SYN3,ACADM,AS3MT,TKTL1,TNRC6C,CDC14B,DPY19L3,NRP2,LDLRAD4,CBR1,MYOM2,ARHGEF2,SLC4A7,CX3CR1,IP6K1,PITPNC1,ZEB2,USP3,NR1D2,TSPAN5,RASGRP1,FRY,NCALD,AMZ2,FCGRT,SORBS1,SARAF,GABBR1,IQGAP2,ACSS1,GABARAPL2,JAK1,PIK3CD,PRKAB2,TMEM206,RXRA,GALNT10,SGK1,CTXN2,PEX26,FNBP1,DBNDD2,STX1A,SULF2,CAMSAP2,TCF7,GPRIN3,LRRC8A,TP53BP2,MEIS3,ADAMTS9" Coexpression M8553 Genes down-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADD3,ALCAM,AMPD3,MADD,CDC25B,ENTPD4,ATRNL1,PITPNC1,GUCD1,RHOBTB1,KBTBD11,DLG4,CD99L2,CACNG7,FGR,PRKAG2,UBE2E3,TMEM107,STAU2,FYN,ZNF274,GRK4,GSN,PADI2,DDX19B,FAAP20,LIFR,SYTL4,GPR155,MBD1,ZNF862,NUCB2,PDE2A,DIRAS2,ERI2,HES6,GKAP1,ZCCHC24,MPRIP,SYT4,CAMTA1,ZMAT3,SLC44A1,THRA,CADM1,MICAL1,KLC2,SLC38A1,TUBA1A,URM1,KLHDC1" Coexpression M3407 Genes up-regulated in comparison of control microglia cells versus those 24 h after stimulation with IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "NDRG2,AP1B1,MYOM1,CACNA1I,NPIPA1,ABCG2,SLC4A7,FEZ2,CSNK1E,RIMS2,RIMS3,RHOBTB1,SGSM2,HS3ST2,DTNA,ABCC5,RTN3,EXTL2,UBE2E3,FOXO3,ZMYND11,SESN1,BRD8,CBX1,PCLO,MUM1,VSIG4,SMAP1,ITPKB,KHK,OLR1,PMP22,REV3L,RPL15,RPS6KA2,RXRA,ASRGL1,ITSN1,EPN2,SLC11A1,NAXD,PALLD,KDM3A,FAM168A,DNAJC9,TAL1,CRB1,TIAM1,TTC3,CADM1,WNK1" Coexpression M387 Genes up-regulated in 4 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "CLK4,TKTL1,ADCY6,SORCS2,ALCAM,PARG,FUBP1,CLTA,CNN3,RBM39,EDRF1,YTHDC1,SLC12A6,TLR7,ST3GAL6,KIAA1109,UBE2E3,STAG2,RAPGEF6,ZNF638,NR3C1,KAT7,MUM1,BACH2,GABARAPL2,JAK1,SESN3,NRDC,PENK,SEPT4,PRODH,SYTL2,C1orf54,PCMTD2,SATB1,SELL,MYCBP2,SPP1,SAMSN1,AGTPBP1,TCF12,SIRT1,ACTR6,METTL3,TRIO,RFTN2,TTC3,TUBB2A,SF1,RNF103,JMJD1C" Coexpression M9787 Genes up-regulated in B lymphocytes: B1 versus plasmablasts. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ACLY,RBM10,AP2A1,ABCD2,ANK1,CNIH2,API5,ARRB2,ATP6V1G2,MYOM1,HIP1R,TAOK2,DNAJB5,NSL1,PLCXD3,DBI,PITPNC1,HS3ST2,EDNRB,CACNG7,TNK2,SRPK3,FGFR1,SEMA6C,GAB1,GLUL,TPPP,CELF3,AGBL5,KCNJ3,NFIA,NOS1,SETD4,OCRL,GNG2,EPN1,POU3F2,RANBP3L,RIPOR1,TTC13,QDPR,SH3GL2,DBNDD2,NCDN,INKA2,NACC2,SPHK2,HPS4,ACTR3B,SLC39A12,ST8SIA2" Coexpression M3233 Genes down-regulated in comparison of regulatory T cell (Treg) treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "EMILIN3,TMCC3,AMER3,VXN,CDC25B,KMT2C,CLOCK,CSNK1E,CMTM5,HDAC9,PHF19,SCRN1,SIRPA,C8orf34,AK5,PHF20L1,PLXNC1,EPB41L1,FGFR3,GABRG2,SYT17,GP1BB,STMN2,C2CD4C,KCNQ2,TTYH2,ASPRV1,MAP4,MARK1,MITF,MYO6,NTRK3,EPDR1,SLC26A11,PTPRN,RBBP8,NEK11,SORCS3,KIF1B,SRPK2,VAMP1,TAC3,PDLIM2,WSCD1,ASXL3,BEX4,PRMT8,CELF4,LAMP5,SLC17A6,FAM181A" Coexpression M7518 Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "GRAMD1B,ZNF608,APBB2,LRRC4C,MYOM1,ARHGEF7,RCBTB2,TJP2,AKAP7,ABCG1,CSNK1G3,PITPNC1,SRGAP3,SEMA3D,FRY,ARMCX1,FOXO3,SESN1,PARD3B,BACH2,HLF,CELF5,LRRCC1,MAP4,NFIA,PKD1,RETREG1,PPP2R5C,ARID4A,TRIM68,MEG3,PEAR1,ANKRD6,SLC12A2,EPC1,TMCC1,TNIK,FNBP1,CAND2,CDK19,CEP68,TCF4,TCF7L2,STXBP4,TSC1,TTC3,AMOT,VLDLR,ZIC1,PHTF2,PIANP" Coexpression M9002 Genes down-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg1 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ADCY2,AP2A2,AP1B1,FGD2,GAS7,DGKD,CACNA1I,ENTPD6,REPS2,ZBED1,DCLK1,ASIC3,CHN1,CHN2,TPP1,IFFO1,OSBPL3,CST3,INTS1,IP6K1,C2CD2L,ABCC5,LPAR6,GABBR1,SCIN,LMO2,MAN2A2,MEF2C,MX1,ZNF862,NUMA1,PLCB2,WBP1L,PTPRH,RIPOR1,RNF220,RNASE1,ZNF671,SEC14L1,ASRGL1,ITSN1,ARFGAP1,TSPYL2,LHPP,ACSBG1,GORASP1,MTCH1,MICAL1,NSD2,PLSCR4,NUP214" Coexpression M7596 Genes up-regulated in CD11b+ from spleen of healthy C57BL6 versus CD11b+ cells from tumors of C57BL6 mice bearing EL4 lymphoma. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ABAT,ABR,CLK4,ADD3,ADRB2,OGT,DGKD,N4BP2L1,CBFA2T2,CX3CR1,ZNF337,MAML1,GIT2,ZC3H11A,USP3,ABI1,ABCC5,IRAK4,ING4,MRNIP,EPB41,ATP8A1,IP6K2,FOXO3,MSL3,BTN2A1,PSIP1,KLF12,DIPK1A,VWA5A,MXI1,LYRM9,NACA,CCSER2,ING3,PPP3CC,PKN2,PTCH1,BSDC1,RPS20,SATB1,CASC3,SON,MYCBP2,CLASP1,ZMYND8,UBE2H,ZNF32,ZNF189,UPF3A,PARP6" Coexpression M7998 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.65E-04 1.00E+00 2.47E-03 2.45E-02 51 200 "ACTN1,RNF150,ARHGAP5,C5,DIRAS1,CAST,SYNGR3,PLEKHB1,NDST3,CDC42BPB,CSF2RA,UBXN2A,PHF14,CYBB,MYADM,SCRN1,AIF1L,DBN1,CDON,DOCK2,E2F5,EPS8,EZH1,STAG2,LPAR4,GPR26,NR3C1,PTPRT,FICD,IGFBPL1,IL6ST,MYO9A,PCDH8,PLP1,PRKAB2,MTMR10,PTPRE,ARID4A,SCN2A,PPM1E,RCOR3,STAC2,C3orf70,ANKRD12,EXOC7,SIK3,ATP6V0E2,AMZ1,RNF103,FXR1,SENP7" Coexpression 18062813-GeneList Rat Breast_Moral07_163genes_BBP_treated GeneSigDB 1.66E-04 1.00E+00 2.48E-03 2.46E-02 31 104 "ABAT,ADD1,RASL11B,AZGP1,ARHGEF7,GPC2,BSN,CAMK2B,ARHGEF1,CDH8,DLGAP2,CELSR3,GABBR1,GABRG2,GAD1,GRIK4,GRIN2D,GRM5,HSF2,HTR2A,NDUFA5,OXTR,PTHLH,RNASEL,SCN2B,SLC12A4,SYT1,MCF2L,TCF4,TNR,TSN" Coexpression 15277230-Table3 Human Thyroid_Morrison04_11genes GeneSigDB 1.66E-04 1.00E+00 2.48E-03 2.47E-02 7 10 "ADAM23,NRXN3,NTM,FOXG1,SORBS1,ST8SIA5,PPP1R1A" Coexpression 15374961-Table2 Human Brain_Freije04_44genes GeneSigDB 1.68E-04 1.00E+00 2.51E-03 2.49E-02 17 44 "HDAC4,EDNRB,CALCRL,DLL3,MSTN,CSDC2,ITPKA,NTRK2,PACSIN1,CRTAC1,RGS4,SNCB,SNCA,SYT1,SYT5,HEY2,VSNL1" Coexpression M2205 Genes up-regulated in immature bone marrow progenitor cells upon knock out of CBFA2T3 [GeneID=863]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.69E-04 1.00E+00 2.52E-03 2.50E-02 87 387 "AS3MT,MTUS1,ABCD2,ANK3,GAS7,APP,LGR5,CASK,CDK5R1,KALRN,ARHGEF2,B4GALT6,HOMER3,ARHGEF6,SLC4A8,SLC32A1,ABCG1,AATK,ATRNL1,CX3CR1,ARMCX4,RHOBTB1,EBF1,KLHL5,EBI3,PLEKHA1,RASGRP2,IGSF6,FLT1,HVCN1,NEK6,C15orf41,GBX2,GFRA1,GGTA1P,GPT2,B4GALNT4,ADAP1,PARD3B,RASSF8,HNMT,HP,HSD17B1,ICA1,NIM1K,HES5,ITPKB,LMO1,LDLRAD3,TM6SF1,SCAMP5,MDGA1,MYO7A,NCF2,OLR1,P2RX7,PDE2A,NALCN,LRP12,PRODH,C1orf54,SLC6A15,ATP8B4,PLPPR3,KCNIP3,WLS,CHD9,CXXC4,TRERF1,BEX1,SPTAN1,STOX1,SSTR2,DNMBP,DOCK9,TEK,ATP13A2,TF,TMOD1,NPL,TPM4,TTPA,STOX2,NAV2,PLD4,GOPC,CERS6" Coexpression 18405367-Table2a Human StemCell_Tondreau08_58genes GeneSigDB 1.69E-04 1.00E+00 2.52E-03 2.50E-02 19 52 "CASK,NRP2,SLC16A4,CLCN3,SNCAIP,GOLT1B,ETV1,ACSL4,SYNCRIP,GALNT15,NEGR1,KCNK1,SYTL4,PCSK1,PDE4B,PENK,CDK5RAP2,LRP8,NETO2" Coexpression 18332912-Table2 Human StemCell_Oh08_58genes GeneSigDB 1.70E-04 1.00E+00 2.53E-03 2.52E-02 18 48 "LRRC4C,CADM3,CANX,PLEKHB1,ACBD5,RASSF2,CTIF,JAKMIP2,DLG2,NCALD,ZNF585B,MEIS1,SCN2B,ZNF430,TPD52L2,CHST5,EIF4ENIF1,VAV1" Coexpression M17163 Genes up-regulated at early fetal liver stage (embryonic days E11.5 - E12.5) compared to the late fetal liver stage (embryonic days E14.5 - E16.5). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.78E-04 1.00E+00 2.64E-03 2.62E-02 44 166 "TMEFF1,WASF1,PTBP2,LDB2,LARGE1,SOCS6,ARMCX2,HEPH,DLG3,GOLT1B,EDNRB,SEMA3D,PCOLCE2,ARMCX1,FGF13,FGFR1,EVL,LPAR4,MEST,MYCN,NNAT,PDGFRA,CDK14,SERPINE2,PKM,KCTD15,LRP12,PTN,PTX3,WLS,SATB1,SH3GL3,SLC12A2,SMARCD3,PDZRN3,RBM34,PDZD2,ZNF423,SYNE2,EHBP1,TRO,TRPS1,TTC3,RPRM" Coexpression M8268 Genes down-regulated by flavopiridol [PubChem=5287969] in the HCT116 cells (colon cancer) depending on their TP53 [GeneID=7157] status: wild-type vs loss of the gene's function (LOF). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.79E-04 1.00E+00 2.66E-03 2.64E-02 32 109 "ADD3,BIN1,CACNA1G,CAMK2G,SLIT2,TCAF1,KIAA0513,ZNF337,B3GAT3,MED12,CAP2,STARD3,GPER1,NR3C1,RNFT2,HMGB1,KHK,KIF5C,SCAMP5,MSI1,PALM,RETREG1,RALGDS,ZNF532,CCDC92,PEG10,MGRN1,PARD3,TRPC1,MICAL1,NSD2,SEMA3B" Coexpression M380 Genes up-regulated in dendric cells: untreated versus LPS and anti-CD40. MSigDB C7: Immunologic Signatures (v6.0) 1.80E-04 1.00E+00 2.68E-03 2.66E-02 45 171 "AS3MT,GRAMD1B,USP28,ARHGAP5,ATP2B1,MAP4K4,CX3CR1,RIPOR2,KBTBD11,CPEB2,TSPAN5,PLXNC1,RASGRP2,DNAJC27,RCSD1,FGF13,MAD2L2,BRPF3,IQGAP2,RAPGEF4,BACH2,IL6ST,JAK1,GPR155,MBP,SLC11A2,PDE2A,PDE1B,PIK3R1,NLE1,PRKAB2,PRKCB,SIDT1,RXRA,SELL,RASA3,DZIP1,USP33,KIF1B,RAP1GAP2,TCF7,FRYL,PIK3R5,RUNDC3B,NETO1" Coexpression 14766275-Fig.2 Human Uterine_Ferguson04_101genes GeneSigDB 1.82E-04 1.00E+00 2.69E-03 2.68E-02 26 82 "ADCY2,SGCE,MAP7,CDO1,ARMCX1,FHL1,FLNC,HLF,MAOB,MEF2C,MEIS2,MYO6,FXYD6,PDE2A,FXYD1,PMP22,SMTN,SNAP25,TACC1,TGFBR3,THRA,TPM1,TPM2,TRPC1,RPRM,MPPE1" Coexpression M16369 Genes whose expression negatively correlated with resistance of breast cancer cell lines to dasatinib [PubChem=3062316]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-04 1.00E+00 2.71E-03 2.69E-02 23 69 "PLEKHH1,KIAA1324,EPB41L5,CA12,CALM1,SCARB1,CHRM1,EPS15L1,ABCG1,GREB1,MYEF2,STARD10,SPIN1,ICA1,MAPT,ACSS3,ARX,SLC1A2,CBX5,TPD52,TRPS1,SLC38A1,CERS6" Coexpression M4242 Genes up-regulated in monolayer (2D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.84E-04 1.00E+00 2.71E-03 2.69E-02 23 69 "ADAR,TMEFF1,COPB2,TAOK2,CSF3R,DCTN1,ACOT8,SRRM1,DNAJC27,HPGDS,STARD3,GPR19,GUCY1A1,HMGCL,LSS,MYL3,PDYN,REV3L,SMARCE1,SPTAN1,TGFBR3,KCNE5,SPHK2" Coexpression M1912 Genes up-regulated in neural stem cells (NSC) at 36 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.85E-04 1.00E+00 2.73E-03 2.71E-02 55 221 "ADCYAP1R1,SORCS2,IGDCC4,MARK4,KIF1A,ADAM15,GPR146,ARHGEF2,CRLF1,DNAJB5,CSF1,SDC3,SIRPA,FBXO25,ARNT2,DNM2,DMTN,FCGRT,OLFM1,SORBS1,CAMKK2,STARD10,OS9,GSN,GSTM5,TUBB2B,KCNC1,KCND3,VWA5A,SCAMP5,NNAT,PDE2A,TMEM38A,TNPO2,POU6F1,MAPK10,SLC22A23,GDPD2,PTPRE,PYGM,RALGDS,RXRA,S100B,DGLUCY,EFHD1,SOX3,KIF1B,MAPK8IP3,SEPT8,STXBP1,ZMAT3,NACC2,CBX5,TNS1,RPRM" Coexpression M9991 Genes up-regulated in B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.86E-04 1.00E+00 2.74E-03 2.72E-02 48 186 "DSCAML1,ERMN,BCAR3,SLC16A4,TMEM257,CDH18,CNR1,AKAP5,PLXNA4,ZSCAN23,MAGI2,NTM,AK5,E2F5,WDPCP,FRY,ANKMY1,APOPT1,ATP2C1,GDF9,LYVE1,MCHR1,ATP2B1-AS1,FAM19A2,GPR45,RAMP2-AS1,LAYN,OTOGL,KCNK10,PMP22,PRKCZ,HES6,ASIC4,KIF27,SCMH1,IGSF9B,SOX1,KDM3A,DIP2A,TMEM150C,AGTPBP1,CUX2,PCDHGA10,ZNF346,SYNPO2,PRR18,RGMA,FAM181A" Coexpression M2643 Genes down-regulated in BJAB (lymphoma) cells by rapamycin (sirolimus) [PubChem = 6610346]. MSigDB C6: Oncogenic Signatures (v6.0) 1.87E-04 1.00E+00 2.75E-03 2.73E-02 49 191 "ACHE,MTMR3,MTMR2,CACNB4,COL9A1,COL9A2,CRMP1,CRY2,LRIG1,EDRF1,PHYHIP,SEC16A,DPH1,GABRB1,GFRA2,GLUL,GPR12,GRIN1,GRM1,GRM2,CIT,SMAP1,IL11RA,SMAD9,MID1,MOG,MYCN,NHLH1,NUMA1,PCSK2,FTO,FXYD1,PSD,PSMD13,PTCH1,RAB5B,CNKSR2,KDM4B,WDTC1,SOX10,DDN,FAM168A,TACR1,CDH22,TRPM2,WNK1,GDPD5,PCBP4,FAM182B" Coexpression 20140255-TableS2 Mouse EmbryonicStemCell_Romito10_276genes GeneSigDB 1.88E-04 1.00E+00 2.75E-03 2.73E-02 52 206 "ANK1,MARK4,SLC4A4,CADM3,ADAM15,CACNA1G,HIP1R,NOG,SYNPR,CHRNB2,JAM2,IFFO1,CSF1,RGS6,SDC3,AIF1L,PITPNC1,TIAM2,DTNA,DUSP9,ABCC5,RASA4,F3,CACNG3,FCGRT,FOXM1,TPK1,GABRG1,GJB1,GRB10,GSN,SYNPO,HPCA,IL12A,SLC11A2,DDR2,OPRL1,PMP22,KLK6,CNNM2,PTPRB,ARHGEF10L,SH3GL2,FHOD3,FGD4,ATP11A,SATB2,TCF7,SYNE1,SLC13A3,PLD4,NETO1" Coexpression M7410 Genes down-regulated in immature neuron cell line: control versus interferon alpha (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.88E-04 1.00E+00 2.75E-03 2.73E-02 50 196 "NDRG3,ADRB2,USP35,APBB1,ATM,ST3GAL5,CASTOR3,ARHGEF1,CDC25B,PLEKHB1,IPCEF1,RIPOR2,SNPH,KIAA0513,PITPNC1,RABGAP1L,NR1D2,OPTN,ABI2,SORBS3,ING4,EZH1,HPCAL4,FYB1,SESN1,NTNG2,PRRC2B,MBP,MXI1,NUMA1,PDE3B,PDE4D,PFKFB4,PIK3R1,SLC26A11,GRAMD1C,GAL3ST4,SOX6,FAM102A,NBPF1,SIRT2,EPC1,SYNE2,VAMP1,CAMSAP2,ZMAT3,MICAL1,WNT7A,ITM2C,FAM219B" Coexpression M1746 Genes with promoters bound by FOXP3 [GeneID=50943] and which are up-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.88E-04 1.00E+00 2.75E-03 2.73E-02 50 196 "ADD3,ARHGAP5,ATP2B1,LDLRAD4,CAST,LRIG1,ARHGEF10,IPCEF1,TOX,TBC1D5,RABGAP1L,GPHN,SLC37A3,HBS1L,RAPGEF6,SESN1,MALT1,DBF4,NR3C1,AP4S1,DIPK1A,MBNL1,MYO9A,PDE4B,PIK3R1,STRN3,PPP2R5C,PPP3CC,ATG16L1,ZYG11B,RFX3,TRA2B,DOCK10,CHD9,WDR37,SLA,ZKSCAN3,CDK19,ANKRD12,TCF12,GPRIN3,SIK3,KAT6B,TRIO,RUNDC3B,TBC1D15,WNK1,EVI5,PHTF2,JMJD1C" Coexpression M17082 Genes up-regulated in hematopoietic progenitor cells (HPC) of T lymphocyte and NK (natural killer) lineage. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.99E-04 1.00E+00 2.91E-03 2.89E-02 25 78 "ANK3,CDC14B,MPDZ,CACNB2,CHN2,TJP2,CRHBP,LRIG1,ARMCX2,DNAJC6,ARMCX1,HLF,PBX1,SERPINI1,PTK2,PTPRD,MEG3,CCDC88A,PDZD2,BEX1,TAL1,WASHC4,TPM1,TRO,FXR1" Coexpression 19286929-SuppTable2c Mouse Lung_Rangasamy09_13genes GeneSigDB 2.04E-04 1.00E+00 2.98E-03 2.96E-02 8 13 "CAMK2D,CAMK2G,RASGRP1,SMC2,CAMKK2,MAPK8,MAPK12,HHIP" Coexpression M8819 Genes up-regulated in Foxp3-ires-GFP T conv (FOXP3- [GeneID=50943]): B6 versus NOD background. MSigDB C7: Immunologic Signatures (v6.0) 2.07E-04 1.00E+00 3.02E-03 3.00E-02 38 138 "WDR35,NCOA1,ATP1A3,SYNJ1,SYNJ2,JAZF1,CAMK2D,PLCXD3,ARHGAP24,DSCAM,TSPAN5,CHST15,STARD10,GPR26,GUCY1A1,GUCY1B1,GPR45,SYNPO,IRF8,SCIN,INPP5B,LIMS1,SYTL4,HECTD2,NF1,NTRK3,CNNM2,PTCH1,PEX2,SH3GL3,FAM81A,SLIT1,GLT8D1,GPRIN3,GZF1,HEY1,TMEM63C,IFT88" Coexpression M8892 Genes down-regulated in pro-B cells versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 2.08E-04 1.00E+00 3.04E-03 3.02E-02 45 172 "ACLY,ARNTL,ARRB1,ASPH,JAZF1,RAB29,CAMK2G,AKAP7,C2CD2,SH2B1,FBXL5,SRGAP3,CD320,POLK,GPR153,SDCBP2,GABBR1,GALC,GGTA1P,SPIN1,PTPN5,KLF12,HMGCR,HTR2A,ICA1,ITGAV,LRRC49,PTPN13,PLEKHB2,ATXN1,SCP2,SGK1,ZCCHC24,NXT2,TTBK2,STXBP1,SYNE2,SLC37A2,ARL10,UBC,DNAJC12,LAT2,EVI5,PPP1R3F,PCBP4" Coexpression M19261 Genes specifically expressed in samples from patients with pediatric AML (acute myeloid leukemia ) bearing t(8;21) translocation. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.10E-04 1.00E+00 3.06E-03 3.04E-02 83 368 "ABR,ACTN2,AP1B1,APP,MTMR9,BTK,MYRF,DDR1,RUNX1T1,CDH2,DLGAP2,CDR1,CACNA2D2,ARHGEF6,CSF3R,SIPA1L1,SOCS5,SCRN1,BRINP1,ELMO1,CEP170,LYPD1,SACS,MED12,DPYSL2,GNE,SH3GLB1,EPB41,EPB41L2,NCALD,SCML2,TRAF3IP2,ZNF274,HPGDS,GLS,GNAS,GPM6B,GRM8,BTN2A1,GUCY1A2,GUCY1A1,JAK1,KIT,LIMS1,MEIS1,CD200,NAP1L1,NBL1,NFIX,NTRK3,NUMA1,PALM,CDK14,SERPINE2,PIK3R1,PLTP,ARID4A,RFX5,RGS10,RNASE1,ROBO1,ATXN1,CLSTN1,SLA,SLIT1,KDM4B,ZC3H13,SPART,SST,CEP68,ANKRD28,PSD3,TEK,TRH,TRIO,TSC2,TTC3,VLDLR,CLDND1,MPPE1,NELFE,NUP214,CERS6" Coexpression M8894 Genes down-regulated in multipotent progenitors versus pro-B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.10E-04 1.00E+00 3.06E-03 3.04E-02 46 177 "ANXA7,PPP4R4,ADAM15,SYNJ2,ARHGEF7,CAST,TPP1,AKAP7,CREM,CSF1,CTNND1,CEP170,CD99L2,ARRDC4,SNX29,EGR3,KATNAL1,ATP8A1,SORBS1,GGTA1P,ZHX1,HSF2,ITGAV,KIT,LIG4,MXI1,PDE1B,PLCL1,CNNM2,LRRC49,PTAFR,MAPK12,ANKRD6,ABLIM3,ZFP1,KIF13A,TEX2,ERC1,SYPL1,SLC37A2,DDHD2,IQCE,AHCYL2,DNAJC12,NAV2,PHTF2" Coexpression M8187 Genes down-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 2.10E-04 1.00E+00 3.06E-03 3.04E-02 46 177 "ADD1,ADD3,ALCAM,DGKD,ATP6V0A1,DOCK11,SYNJ1,CACNA1I,CDC25B,ANKRD44,CSNK1G3,MYADM,RIPOR2,FAM107B,FRY,PAN3,RASGRP2,CHST15,GPD2,ADAMTS6,BACH2,IRF8,DIPK1A,JAK1,JAK2,LMO2,MEF2C,CD200,PDE2A,PDE4B,RETREG1,PPP3CA,SATB1,SELL,RASA3,ATF7IP,LMBRD1,KIF21B,ARHGAP26,CDK19,STAC2,DNAJC9,TPM3,SSBP2,RICTOR,TUBA1A" Coexpression 18381423-SuppTable1a Human StemCell_Riggi08_262genes GeneSigDB 2.12E-04 1.00E+00 3.08E-03 3.05E-02 47 182 "BEND6,SRPX,CEP126,NRP2,CA12,PRC1,LRRFIP1,CLGN,CHI3L2,CLU,ZNF521,VCAN,HEPH,NR1D2,ECM2,EBF1,EGFR,PCOLCE2,ETV1,SCARA3,GALNT15,GPER1,HAS2,SCRG1,HNMT,KCNK2,KITLG,MMP16,CLDN11,PDE1A,PDE4B,PDGFRA,GNG2,ANLN,GPSM2,PRRX1,PTN,VEPH1,RPS6KA2,WLS,TNFRSF19,FHOD3,SLC2A5,PDZRN3,PLCB1,PSD3,TGFBR3" Coexpression M1350 Genes up-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.12E-04 1.00E+00 3.08E-03 3.05E-02 105 487 "KDM5D,ADARB2,ARHGAP20,TRMT9B,PHYHD1,RASL11B,DDX3Y,ATP1A1,N4BP2L1,ADGRB1,SEC11C,IL33,CALB1,CALM1,USP2,CDH8,ADGRG1,SYNPR,CLU,FAM149A,COL4A5,COL9A3,TBPL1,PLCH2,SIPA1L1,USP6NL,HDAC9,AIF1L,KBTBD11,DLG3,EDN1,LPAR6,TENM1,PCOLCE2,CALCRL,RCSD1,NRN1,SH3YL1,ACSL4,EFEMP1,FGF12,FGFR3,CSPG5,FUT9,SALL3,MTHFD2,ATP8A2,ACSS1,STARD10,DNER,IGSF5,ADAM28,GLUL,KCNMB4,GSN,MFSD2A,WIF1,GABARAPL2,KCND2,KCNJ16,KCNK1,KIT,LAMP2,VWA5A,GPR155,MBP,MDFI,AFF1,N6AMT1,PCDH9,PENK,ZFYVE21,PLCD1,SMOX,DRAM2,GDPD1,MASP1,GDPD2,ELOVL2,PTN,PTPN13,PID1,ZDHHC14,SGK1,HKDC1,SLC12A2,COLGALT2,SMOC1,ARC,SEMA4A,PDLIM2,TRIM2,FAM189A1,AHCYL2,HHIP,C9orf85,CA14,TST,RPRM,FAM155A,VLDLR,LYPD6,SEMA3B,WNK2,CBLN2" Coexpression M78 "Genes up-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.13E-04 1.00E+00 3.08E-03 3.06E-02 52 207 "ACHE,BIN1,AQP6,ARSF,MYOM1,CAMK2B,TAOK2,MYL6B,QKI,ARHGEF6,PDE4DIP,FAM131B,RUSC2,C2CD2L,SRGAP3,DMPK,FAM13A,ING4,CALCRL,EFS,FER,FHL1,PDLIM5,FYB1,GJB1,GNAO1,ADAP1,GPR37,GRIN1,MEF2C,MYBPC1,MYH3,NCAM1,TNPO2,MAPK7,MAPK10,PYGM,MRAS,BCAN,ABLIM3,SLC12A2,SLN,SCN3B,CLSTN2,SST,EPB41L3,TNS1,TPM1,TTC3,LAT2,XRCC4,REEP1" Coexpression M359 Genes down-regulated in macrophages from patients with synovial fluid rheumatoid arthritis versus monocyte-derived macrophages from healthy persons. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 39 143 "TKTL1,ADGRB3,DST,SYNJ1,CDC42BPB,RNF14,CST3,APPL1,GREB1,FRMPD4,SV2A,MTX3,ATP8A1,STAU2,FAM120B,FUT10,ARHGAP12,MBNL1,PDE1A,SERPINI1,PKD1,PRKAB2,MAPK10,SIDT1,MAPK12,SCG5,KIF16B,ZFP1,TROVE2,DDHD2,SZT2,PDIA2,RICTOR,ATP6V0E2,GOPC,CERS6,SNX14,IFT88,CPNE4" Coexpression M6341 Genes down-regulated in Vd1 gamma delta T cells: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 39 143 "UPRT,ARNTL,ATP2B1,CADM3,CFLAR,NGB,MYOM2,MYL6B,OSBPL3,NCAN,CX3CR1,CEP170,DLG4,DNM1,NR1D2,EPS8,CDHR1,GABBR1,NCKAP1,STARD10,GCNT2,GPD2,ADAMTS6,JAK1,KLRC2,PIK3AP1,NPTX2,CLEC9A,OMG,XRN1,ATP8B4,SCN8A,TRIM46,DOCK10,ARHGAP26,RAP1GAP2,SYPL1,ARHGEF12,PLSCR4" Coexpression M6812 Genes down-regulated in dendritic cells: control versus stimulated with anti-CD209 [GeneID=30835] antibody. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 39 143 "ASPHD1,GPRIN1,DISP3,PDZD4,FGD2,APOC1,BSN,CD86,NRXN2,LRRC3B,FAM169A,PITPNM3,EFNA3,CGREF1,ARPP21,RUNDC3A,FAM19A2,BVES,UBE2QL1,BTBD17,SCRT2,MOBP,SERPINE2,SSH1,CAMKV,JAKMIP1,PSD,PTH1R,STRC,FEZF2,MRAP2,STOX1,VWA3A,THBS4,FBXL16,CSMD1,PIK3R5,CDK20,TRPM2" Coexpression M8338 Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 50 197 "DPF1,ANK1,CDK5R2,CACNB2,KALRN,ARHGEF1,CDH2,PPT2,LYPD1,TOM1,OPTN,DMTN,ETV1,FGF1,SEMA6C,MALT1,GLI2,GRIK3,NR3C1,RASSF8,SYNPO,IL6R,ITPKB,MYO7A,ZNF862,CDK18,PLCD1,PLEC,MINDY2,RAD51D,RAP1GDS1,RGS3,RGS10,MYT1L,SP4,ST5,AJAP1,FAM168A,VAMP1,PHF24,LEFTY2,ICAM5,TNFRSF1B,R3HDM1,TNNT1,TPM2,UBTF,NSD2,SLC30A3,ADAMTSL3" Coexpression M4662 Genes down-regulated in comparison of PD-1 high CD8 T cells versus PD-1 low CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 50 197 "NDRG2,KLRC4,TMCC3,CARNS1,GOLGA7B,PITPNM2,GAS7,ARRB1,BCL2L2,LDHD,SEPT7,TJP2,TMEM184B,PLXNA4,KATNAL2,JAKMIP2,MAGI2,USP3,ATL1,FRY,TENM1,RGS17,NCALD,CD320,IQCG,SPECC1,GPR153,GLUL,GPER1,ACOT7,LRRCC1,ITGAM,KLRC3,PIK3AP1,TM6SF1,NCAM1,TBC1D25,PDE4A,ASPDH,PRKACB,USP47,ATP8B4,RXRA,DRAXIN,LIMCH1,ZMAT3,TLR4,RUNDC3B,LAT2,FRMD6" Coexpression M8159 Genes up-regulated in HEK293 cells at 6h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing wildtype NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 2.14E-04 1.00E+00 3.08E-03 3.06E-02 50 197 "NME5,ALK,PLA2G4C,ASPH,ATP2A2,KSR1,THSD7A,RHBDL1,KRIT1,INA,DCLK1,AKAP12,ZNF804A,DYNC1I1,HEYL,EFNA3,SH3GLB1,IRAK4,VPS13B,PTK2B,ARFIP1,GFAP,PRUNE2,GPR17,KLRC3,MAP2,NCAM2,NELL1,SMOX,SEPT4,PILRA,PPP2R2B,PTPRD,RGS12,PAAF1,PKNOX2,SOX11,SYP,FBXW11,KIAA0930,TRIM2,TGFBR3,TLL2,PPIL6,ZNF154,CAB39L,PHTF2,ZNF248,FXR1,JPH3" Coexpression M3654 Genes up-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.16E-04 1.00E+00 3.10E-03 3.08E-02 93 422 "ZNF608,APBB2,ARHGDIA,ARNTL,RASL11B,ALDH4A1,C1QC,IL33,PTBP2,ZBED5,CNOT8,TPP1,CNN3,CP,PREPL,RNF14,VCAN,PPP1R16B,SDC3,CFAP61,CX3CR1,ARHGAP24,MATR3,HP1BP3,DOCK2,EDN1,MBNL2,LPAR6,CALCRL,EIF1,ETV1,TLR7,FAM198B,ST3GAL6,FGF1,SCARA3,FOLR2,DKK3,GABRA4,ERAP1,ARFIP1,HPGDS,HTATSF1,GPR34,LINC01089,GSN,FRMD5,PACSIN2,MIER3,VSIG4,HNMT,IRF8,JAK2,PAXBP1,MAT2A,MSR1,P2RY13,SFR1,NFIA,NPPA,NTRK3,ENPP2,SERPINE2,PRRX1,MINDY2,TATDN3,PTK2,RDX,GTDC1,RGS4,RNASE1,UEVLD,ST6GAL1,ST3GAL3,SLC8A1,SLC11A1,SLN,SS18,NECAB1,ARHGEF9,SYPL1,ANKRD12,FBXW11,ZEB1,TLR4,UCHL1,VSNL1,RICTOR,ZNF540,SPIRE1,ZFAND5,PLSCR4,NHSL1" Coexpression M789 "Genes down-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 4 h time point that were not down-regulated at the previous time point, 2 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.19E-04 1.00E+00 3.14E-03 3.12E-02 61 253 "RBM10,SPOP,PARG,PDXK,NOL4,BARD1,CACNA1E,RUNX1T1,SYNGR3,CSF1R,MICAL2,SOCS5,PPP1R16B,ARHGEF4,RIPOR2,B3GAT3,RABGAP1L,DNAH9,DYRK1A,OLIG2,LRRC17,EPHA5,ETV1,KAT8,ZNF274,AHDC1,GFAP,GRM5,CIT,AP4S1,HMGCL,INPP5B,KCNF1,MATK,NFYA,ODF2,PDE4B,PLEC,POLG,PRKAB2,PRKCB,RAD17,SLC6A15,RGS4,RXRA,SBF1,SCN8A,SUPT20H,SLC1A7,SON,SOX1,NMNAT2,MPRIP,DNMBP,NR2E1,METTL3,UGT8,ZNF23,ZNF195,PRDM2,LRP8" Coexpression M8814 Genes up-regulated in FoxP3-IRES-GFP: NOD T reg (FOXP3+ [GeneID=50943]) versus B6 splenocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.25E-04 1.00E+00 3.23E-03 3.20E-02 41 153 "ABR,AXIN2,ADORA2A,LTBP4,CNTNAP1,FAM131A,ARNTL,CADPS,NCOA1,ATP2B1,DPY19L3,KSR1,SYNJ1,BAIAP3,NCOR1,PLCXD3,KIF26A,SPOCK2,MFAP3L,DTNB,FRY,LPAR6,WAC,FGR,TRAF3IP2,NCKAP1,STARD10,NR3C1,GUCY1A2,IGF1,GPR155,CLDN11,PIK3C2A,PLCD1,RC3H2,PTH1R,SUSD4,PEAR1,ANKRD6,ACSBG1,TIAM1" Coexpression M945 Genes up-regulated in normal bone marrow plasma cells (BMPC) compared to polyclonal plasmablasts (PPC) that also distinguished multiple myeloma (MM) samples by expression of levels of TACI (TNFRSF13B) [GeneID=23495]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.28E-04 1.00E+00 3.26E-03 3.24E-02 28 92 "PI16,APOC2,PPFIA3,PRX,AZGP1,DDR1,CCDC151,PICK1,AKAP7,COL11A2,HS3ST2,MAMLD1,DMTN,C1orf61,GABBR1,GGTA1P,C1QL1,TUBB2B,KCNH2,MBP,MITF,GIT1,NPPA,NTRK3,PIK3CD,RPL38,SLC6A8,SOX15" Coexpression 17823248-Table2 Mouse Breast_VanHouten07_49genes GeneSigDB 2.31E-04 1.00E+00 3.30E-03 3.28E-02 17 45 "ATP2A2,ATP2B2,CACNA1G,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CACNB2,CALB1,CALB2,CALM1,CACNG2,NUCB1,NUCB2,RYR1,RYR3,TRPC1" Coexpression M2778 Putative metastasis genes: up-regulated in metastatic cell lines LM2 (lung) and BoM2 (bone) relative to the parental MDA-MB-231 line (breast adenocarcinoma). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.42E-04 1.00E+00 3.45E-03 3.43E-02 31 106 "KIDINS220,FAM135A,ALK,AMPH,MYOM1,CA8,MTMR7,SLC4A7,HAPLN1,CNTNAP2,KIAA0087,MYEF2,DLG2,DPYSL4,SIGLEC8,GATM,GPR17,PDGFRA,PLP1,PTPRN2,NKAIN1,MARCH1,RADX,KLHL11,ROBO1,NLGN4Y,ST6GAL1,DZIP1,RAP1GAP2,FCHO1,PLCB1" Coexpression M2913 Genes up-regulated in skin from: wildtype (BALB/c) versus IFNG [GeneID=3458] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.43E-04 1.00E+00 3.46E-03 3.43E-02 34 120 "RNF150,KIDINS220,NOL4,BAIAP3,CLU,SULT4A1,NRG2,SEC31B,PABPC5,DSCAM,CACNG3,NRG3,ADAMTS13,SHISA6,KCNJ3,KCNK1,NEUROD2,VWA2,HCN1,GPR137C,CNTN3,MAPK4,ROBO1,GLDN,UNC80,VAMP1,TAL1,CNTN2,TBCEL,TIE1,FSTL5,FZD3,NLRP3,ADAMTS10" Coexpression M2644 Genes up-regulated in BJAB (lymphoma) cells by rapamycin (sirolimus) [PubChem = 6610346]. MSigDB C6: Oncogenic Signatures (v6.0) 2.43E-04 1.00E+00 3.46E-03 3.44E-02 47 183 "FZD9,ADRA1B,ANK1,CDK10,CASK,ASPH,CHRD,NCOA1,ADGRB2,KSR1,MYRF,LHX2,CHD5,KIAA0040,GREB1,CDON,ST8SIA3,FABP7,GRIN2C,VSIG4,SYNPO,C2orf72,ITPKA,L1CAM,SHC3,TAGLN3,NPY,NUCB1,P2RX7,PDE2A,PDE4A,PDE1B,SSH1,PPP3CA,PRKCG,KLK6,PTPRD,SCN2B,STUM,SFPQ,SLIT1,SST,ABCC8,ASTN2,CBX5,AMOT,VGF" Coexpression M8346 Genes down-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.44E-04 1.00E+00 3.46E-03 3.44E-02 50 198 "NDRG2,AGT,EIF4G3,IL33,MYOM2,KIAA1549L,CLCN4,CLTA,COL9A3,AKAP5,PYGO1,SNPH,EDNRA,RABEPK,EXTL2,FCGR1A,GABRB3,GNG4,GPR37,PCLO,GRM7,MSL1,KCNA6,KIT,MEIS1,MEST,MYT1,PAH,TNPO2,RELN,PTPRZ1,RGS7,ANKRD6,SLC11A1,SHANK2,SLCO1A2,SMARCE1,PDZD2,DOK5,SMG6,TCF4,CBX5,RBFOX2,CDK20,TSC1,HSPBP1,FAM155A,UBE2H,UBE3A,SMIM8" Coexpression M9941 Genes down-regulated in B lymphocytes: wildtype versus MAP3K7 [GeneID=6885]. MSigDB C7: Immunologic Signatures (v6.0) 2.44E-04 1.00E+00 3.46E-03 3.44E-02 50 198 "PLEKHG5,ALK,APBA2,CACNA1G,DDR1,ARHGAP33,NOG,SLC22A6,EPS15L1,MYL6B,CNR1,COL9A1,TOGARAM2,NSL1,GNE,TMEM74,CEND1,MED12L,ATP13A4,ABLIM2,HIGD1B,GGT7,PPARGC1A,TMEM121B,GRIK2,GRIK3,WIF1,C2orf72,KCNJ16,MYL3,PDE3A,TMOD2,TMIE,RGS12,KLHL11,CCDC25,SCN4B,TNFRSF19,SLC1A2,SOX3,EMC1,ATP10B,SYNE2,CUX2,PCDHB7,TIE1,KCTD2,PCDH20,DNALI1,FAM181A" Coexpression M7924 Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 2.44E-04 1.00E+00 3.46E-03 3.44E-02 50 198 "KLHL13,ALCAM,AMPD3,OGT,ANXA7,CASK,BCL2L2,DST,FOXK1,LRRFIP1,COX4I1,MYRIP,DZIP3,ARMCX2,CDHR1,ARMCX1,SH3YL1,PRAM1,AGAP3,HVCN1,GAB1,ILDR2,GPR34,RBPJ,DOCK7,INPP1,JAK2,KIT,LIMS1,FXYD7,NELL2,PPP3CA,PTK2,ARID4A,RFX3,RPE,PAQR6,FNIP1,DOCK10,CDK5RAP3,ZCCHC24,TAB2,CEP68,WASHC4,DOCK9,CABIN1,TST,ZNF711,CSDE1,ITM2C" Coexpression M29 Genes whose expression positively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.57E-04 1.00E+00 3.63E-03 3.61E-02 93 424 "KIDINS220,OSBPL1A,OSBPL8,MAP4K3,PKP4,ANXA7,APC,ARHGAP5,NCOA1,NUMB,SCAPER,CAST,KRIT1,SOCS6,RAB28,ARMC8,PREPL,RNF14,NCOR1,MATR3,YTHDC1,FBXL5,DDX46,ABI1,FEM1B,COPS4,DCTN4,GMPR2,AMZ2,SEC24B,KIAA1109,CAMSAP1,NPTN,ZMYND11,NCKAP1,ARFIP1,NFU1,COPS8,CBX1,HTATSF1,RAB40B,STON1,NUDT21,MAP4K5,GYG1,HNMT,SMAP1,RBPJ,KTN1,NAP1L2,NF1,PCMT1,FTO,PPP2R5C,PKN2,MAPK9,VPS13C,RDX,DPF2,RPRD1A,PCMTD2,ATXN1,SCAF8,FBXO11,BTBD3,SEPHS1,ELMO2,RCOR3,LIMCH1,ZNF415,LMBRD1,RBM34,SON,ZC3H13,TAB2,TROVE2,ZNF302,SS18,STAU1,KANK1,NSFL1C,FAM168A,FBXW11,ATMIN,PUM2,AKTIP,BEX4,TSN,USP1,XPO1,UPF3A,HNRNPA3,RNF146" Coexpression 17510434-Table2 Human Breast_Lin07_38genes GeneSigDB 2.57E-04 1.00E+00 3.63E-03 3.61E-02 13 30 "ADORA1,AP1B1,PPP6R2,GRIK4,SFXN5,NCF2,NOS1,GPR173,PPP2R2C,STK32B,SBF1,IFT122,PAK5" Coexpression 18667080-TableS9 Human StemCell_Kocer08_575genes GeneSigDB 2.60E-04 1.00E+00 3.67E-03 3.64E-02 110 517 "ABAT,ACTN1,MTUS1,PKP4,APP,LGR5,DDX3Y,BARD1,SYNJ1,GYG2,CA12,CALB2,CALM1,CAPN3,PRC1,CLDN10,ARHGEF2,CDH10,MAGI1,CDO1,LHX2,EPS15L1,SLC24A2,FAM189A2,COL9A2,RCHY1,TCEAL2,AKAP12,CRYM,MICAL2,VCAN,HDAC9,GPRASP1,TOX,SCRN1,DCT,ZEB2,HEPH,SGSM2,DPYSL2,DNM1L,EDNRA,EDNRB,RASGRP1,SIDT2,PLXNC1,EFS,AMZ2,TUBB4A,ATP8A1,FOXF2,ATP6V1H,FYN,AHCYL1,MALT1,GLDC,GPM6B,STON1,GRB10,GSTM5,WIF1,HBA1,HSP90AA1,MBP,MID1,CD200,MRPL42,HNRNPM,FXYD6,NASP,NOVA1,OPHN1,PCSK2,PDE3B,ENPP2,SERPINE2,PPP2R5C,PSMA6,RIPOR1,PPP2R3C,RDX,UBR7,FBXW7,RPS20,CLIP1,DOCK10,FBXO11,SEPHS1,ARHGEF40,SHANK2,PDZRN3,ZCCHC24,KDM4C,ACSBG1,VAMP1,SYN2,TCF7L2,HEY1,TNS1,METTL3,TRO,TRPS1,TTC3,HIRA,BCL2L13,VSNL1,SLC26A10,REEP1,TUBA1A,NAV2" Coexpression M1098 Genes down-regulated in ME-A cells (breast cancer) undergoing apoptosis upon serum starvation (5% to 0% FCS) for 22 hr. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.61E-04 1.00E+00 3.68E-03 3.66E-02 57 234 "DGCR6,ABHD6,AS3MT,OSBPL6,PPFIA4,PDXK,KIF1A,RGS11,BCL2L2,GPR146,CACNA1G,CA12,COPB2,COG1,ZNF385A,CRY2,TENM4,UBXN2A,MED24,RABGAP1L,TMCC2,DNM1,DUSP9,ENO2,F3,GCNT2,CSDC2,GP1BB,GPD1,KCNH2,KHK,KIF2A,MPP2,NASP,ODF2,EPB41L4B,SH3KBP1,MASP1,ARMC5,ATXN7,HES6,ELMO2,EFHD1,ABTB1,LHPP,THSD1,MAPK8IP3,ATP13A2,TNFRSF1B,TPD52,TPM3,MICAL1,WIPF1,PORCN,NDRG4,ZBTB16,SPATA13" Coexpression M12224 Genes up-regulated in mice with skin specific knockout of RB1 [GeneID=5925] by Cre-lox. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.63E-04 1.00E+00 3.71E-03 3.69E-02 138 673 "TMCC3,ADD1,ADD3,SNX30,TAOK1,CDC42BPA,ANK3,APOC2,APP,LGR5,ASPH,RASL11B,ATM,BACH1,BID,CA4,DDR1,CACNA2D1,CAMK2B,CARS,CLDN10,ZNF445,CFL2,ADGRG1,CLCN3,FADS2,QKI,COL4A5,CP,RNF14,TENM4,PDE4DIP,PUM1,GPSM1,CX3CR1,IP6K1,AIF1L,SIRPA,ZC3H11A,FAM107B,DLX1,DMD,DNM2,ABCC5,HIPK3,EGFR,EIF4G1,EPHA5,SRRM1,PRMT5,FECH,SUCO,SORBS1,PDLIM5,CAMKK2,SDCBP2,HBS1L,ZMYND11,GHR,SPIN1,OS9,GNAS,GPD1,GRK4,GRB10,NR3C1,KAT7,AP4S1,BACH2,HNF4G,IL6ST,ITGAV,JAK1,LIMS1,SMAD1,MSRA,MYH6,NAP1L1,NCF2,NDUFA5,NNAT,SLC11A2,OPA1,CLDN11,PC,PDE3A,PDPK1,TMOD2,PFKFB3,PLEC,SH3KBP1,DRAM2,PPP3CA,PRKACB,PRKAR1B,MASP1,PTPN13,EML5,PTPRE,PTPRG,TUG1,C1orf54,RBBP6,ERI2,RGS4,SEC61A2,BAALC,RXRA,RYR1,TNFRSF19,SMARCA4,SNCA,SOX5,ERC1,SEPT8,PLCB1,PJA1,WWC1,TCEA1,TCF7,TCF12,FRYL,HIF3A,TF,TGFBR3,ZNF106,HHIP,RBFOX2,UBC,UBE2H,PITPNB,BCL2L13,WRN,PMEPA1,NAV2,CAB39L,RTN4,NHSL1" Coexpression 17963910-SuppTable1 Human Breast_Rodningen08_355genes_risk GeneSigDB 2.64E-04 1.00E+00 3.72E-03 3.69E-02 56 229 "EMILIN3,ANXA7,ASGR1,ZBTB10,RUNX1T1,CLU,CNTN1,IQCK,FEZ1,SIRPA,DMPK,CDON,EGFR,EPB41L1,SLC43A2,NRN1,ATP8A1,FCGRT,FGFR1,FHL1,MTHFD2,GSN,GSTM5,KLF12,LAMA2,MATN2,SHC3,MGAT3,KITLG,MT1M,NF1,NFIX,PBX1,PDGFRA,PIK3R1,PLCD1,PCDH18,PPP1R1A,MAPK7,FAT4,MEG3,SLC1A3,SLC6A1,SLC9A5,KIF1B,ADHFE1,SYT11,DNMBP,TCF7L2,PCDHB15,THRA,VAV1,UPF3A,PRDM2,SNX27,ITM2C" Coexpression 20460173-ImmPortCD40LvsControl Human Immune_Kong10_855genes_ImmPort_CD40LvsControl GeneSigDB 2.69E-04 1.00E+00 3.78E-03 3.75E-02 113 534 "ABAT,ADD3,MTUS1,APBB2,CDK13,ASPH,CHRD,ATP1A3,MTMR9,ATP6V0A1,BCL7A,CFLAR,BMP7,DST,BTK,RAB29,DDR1,CACNB4,CALM1,CARS,RUNX1T1,SCARB1,CD38,UBE2L6,CLCN4,LY86,ARHGEF6,CNR1,SH2B1,LRIG1,SLITRK5,KIAA0040,HDAC9,PHYHIP,SCRN1,GIT2,RHOBTB1,RABGAP1L,DPYSL2,E2F5,RCAN2,NCALD,SPEG,PTK2B,TUBB3,CHST15,FDFT1,FGR,ATP5PD,FOXG1,STAU2,FYN,IQGAP2,GPD2,GPER1,RNFT2,HAS2,PTGDR2,PACSIN2,ATXN2L,KLF12,INPP5B,KCND1,KCNN3,KIT,KLC1,STMN1,SMAD1,MEIS2,AFF1,NCF2,NEFM,NRCAM,SERPINI1,PKM,GPSM2,PMP22,PMS2,POLR2F,PPP2R5C,PRKACB,PRKCB,PRPH,SNRK,PTAFR,PTPRE,QDPR,RGS3,RIT2,MAPK12,SBF1,SEC14L1,CLSTN1,SLC2A5,SLC12A2,SMARCA4,WDTC1,IZUMO4,LMO3,POGZ,FCHO1,NCDN,MAPK8IP3,KIAA0930,SYNE1,RBFOX2,LILRA4,ZMYND8,SSBP2,ZKSCAN5,NSD2,ATP6V0E2,PRDM2" Coexpression 15955831-Table6 Human StemCell_Komor05_80genes GeneSigDB 2.71E-04 1.00E+00 3.80E-03 3.77E-02 24 75 "ADCY6,PPFIA3,RGS9,CDC42BPB,RGS6,PDE4DIP,DGKG,PDLIM5,FERMT2,GP1BB,HTR2A,IGF1,ITPKB,MSR1,NRGN,TREM2,PBX1,LRP12,MEG3,SIN3B,ZFPM2,PARD3,TPM4,HRASLS" Coexpression 18955564-TableS2a Human Lymphoma_Miyazaki09_204genes GeneSigDB 2.75E-04 1.00E+00 3.80E-03 3.77E-02 37 135 "VWA5B2,KLRC4,KLHL13,BCHE,BMP7,PCYT1B,CREB5,SEC14L5,AK5,FCGR3A,NPTN,GPR153,GLUL,GPR37,ANKRD36BP1,SCRT2,KLRC2,INSYN2,SLC11A2,PCDH8,PTX3,SH3TC2,SLC6A15,RNH1,LGR4,SLITRK3,SPHKAP,SOX1,HECW1,MLC1,SYN1,TAC1,VWC2,SEZ6L,ZIC1,WNK2,ST8SIA2" Coexpression M2940 Genes down-regulated in CD8 T cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v6.0) 2.76E-04 1.00E+00 3.80E-03 3.77E-02 45 174 "ACTN1,ADCY6,CARNS1,USP28,TNRC6C,NUMB,FOXK1,ABCG1,IPCEF1,SIPA1L1,KBTBD11,PLEKHA1,PAN3,CHST15,RAPGEF6,NEU3,SESN1,TDRKH,RAPGEF4,ELOVL5,IL6ST,MTR,SLC11A2,PDE4B,PIK3C2A,EXOSC10,PACSIN1,SIDT1,EML5,RGS10,SLC25A36,ST6GAL1,DZIP1,TET1,SON,TNIK,POGZ,TCF7,ZEB1,SSBP2,TTC3,MICU3,PARP6,PHTF2,KLHDC1" Coexpression M6577 Genes up-regulated in ITGAM+ [GeneID=3684] cells (incubated for 24h in complete medium) from spleen: healthy versus tumor bearing mice. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ACTN2,TMCC3,SORCS2,GPRASP2,BACH1,SLC25A27,COL11A2,GDA,HP1BP3,RABGAP1L,OLIG1,ATN1,FRY,MRVI1,SH3YL1,TBC1D16,TESK2,CAP2,AFF2,GLUL,GUCY1A1,ATG4C,PADI2,DDX19B,MSL1,TUBB2B,FGFBP3,KCTD6,NFE2L2,PDE2A,ZFYVE21,TNPO2,C19orf57,GDPD1,VPS13C,PTK2,RFX2,FOXRED2,URGCP,TROVE2,STX1A,VAMP1,SEMA4A,PSD3,PRRT1,SMUG1,TUBB2A,CCDC14,REEP1,VANGL2" Coexpression M9994 Genes up-regulated during primary acute viral infection: B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "PTCHD1,BIN1,PKP4,EIF4G3,BCS1L,FOXK1,SEPT7,FOXN3,HECTD1,NCOR1,SCRN1,DBI,LYPD1,PLPPR4,FARSB,EDNRB,ATL1,EEF1D,GPHN,PSMA3-AS1,RACK1,POLR1B,FGF13,FOXG1,DNER,GHR,GPD2,UBE2QL1,MSL1,INPP1,MARK3,SAMD5,NFE2L2,ANLN,PRRX1,RETREG2,SAMD9,PLPPR1,FIGN,RTN1,RAB3GAP1,BTBD7,KDM3A,CLASP1,METTL3,TSN,PCDH20,ZNF142,TMEM237,MFF" Coexpression M4464 Genes up-regulated in comparison of neutrophils versus dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "KIAA1324,ARSF,NOL4,TMEM257,SLIT2,CRYM,CSF3R,RIMS2,RIPOR2,DGKG,SNAP91,PHC2,TMEM35A,EPHB1,ETV1,AFF2,FUT9,B3GAT1,DKK3,SIGLEC8,ALDH1L1,STMN2,TPPP,GRIK1,CIT,PTGDR2,KIT,BCO1,PCDHGC3,PDE4B,GPSM2,NECAB2,MAGEL2,CEP41,RADX,RGS4,RLBP1,LGI2,RORB,PAQR6,SELL,OGDHL,SOX3,ZEB1,HEY1,SLC26A10,LAMP5,SCG2,MPPE1,NUP214" Coexpression M9930 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ERMN,HECW2,GPRASP2,PDZD4,FGF17,CACNA2D1,ASIC3,RAB3C,C4orf33,IGDCC3,DMD,EBF1,CDHR1,RASL12,HPCAL4,FOXG1,C2orf88,DLL3,ARPP21,RAB40B,PRDM5,GRM8,OPALIN,KCND2,KCNH2,LAMA2,CAMK2N2,MGAT3,DDX25,NEXMIF,PCSK5,PDZRN4,PPP1R1A,ELOVL2,PYGM,VEPH1,MAP6D1,SLC8A2,SLC14A1,TET1,PDZRN3,PDZD2,SYN2,PCDHB10,THBS4,ERCC6L2,HIRA,ZIC1,SHD,NETO2" Coexpression M5373 Genes down-regulated in comparison of untreated neutrophils versus neutrophils treated with LPS (TLR4 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "RALGAPA1,ABCF1,CDC7,NME5,AMPD2,ARSF,CADM3,MYOM1,RGS9,FUBP1,CA4,CHGA,TAOK2,SLC22A6,NCOR2,SEC24C,PPP1R16B,CALY,PPP6R2,ARHGAP24,KIAA0586,IST1,MAMLD1,EFNA2,ELN,EPB41,PCYOX1,CAMKK2,CELF1,GABRA4,CSDC2,GOLGB1,GPD1,GRIA1,SLC2A6,KIF5A,ING3,ANKHD1,RALGDS,C1orf54,SCN8A,BCAN,ZNF365,SMTN,SLC6A8,ACSBG1,TCF7,NTSR2,TTC3,LAMP5" Coexpression M4539 Genes up-regulated in comparison of CD8 T cells with progressing HIV infection versus those with controlled HIV infection. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ADRA1D,APBA2,ARHGAP5,CHRD,OSGIN2,CCNH,LGI1,TCEAL2,IP6K1,SPATA2,SEMA3D,EEF1D,EIF1,RRAGB,NBEA,SESN1,LILRB4,TDRKH,SOX21,GUCY1A2,TLX1,MATN2,NBL1,NELL2,OLR1,ABCB1,PRKAB2,PKIA,PPP2R3C,KLHL11,EXD2,GSTCD,RTN1,S100B,TRA2B,FAM102A,HKDC1,SLC15A2,KIF13A,BEX1,PBLD,JMJD6,SYPL1,TSN,SSBP2,TUBB2A,ITM2C,MVB12B,ST7,NUP214" Coexpression M8036 Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus CD8 T cells stimulated by IFNA5 [GeneID=3442] and activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ABR,ACTN1,NDRG3,BIN1,ARNTL,MARCH3,N4BP2L1,ADAM23,RAB29,CAST,MYOM2,CACNA2D2,CNOT8,RCHY1,COX4I1,AHCTF1,BAG4,GPRASP1,ZFYVE16,SPOCK2,SRGAP3,PLEKHA1,RASGRP2,RABEPK,DENND4A,ATP8A1,FCGRT,TRMO,TPK1,ZNF234,ZNF274,PRRC2B,BTN2A1,BACH2,HSPA1L,ICA1,IL6ST,N6AMT1,RGS10,FBXO11,WDR37,RAB3GAP1,ZSWIM8,SAMSN1,PRRC2C,AGTPBP1,TBL1X,TBC1D15,MPPE1,JMJD1C" Coexpression M7453 Genes down-regulated in CD4 [GeneID=920] T cells treated with TGF beta and IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ACTN1,DGKZ,MADD,ARRB1,ARRB2,C5,CCPG1,RCBTB2,TPP1,NMT2,IPCEF1,MYADM,RIPOR2,ZFYVE16,DAPK1,KLHL3,SLC12A6,SORBS3,RASGRP2,RCSD1,FAM198B,GABBR1,SEPT9,ADAM28,TTYH2,MITF,MSR1,NCAM1,NFE2L2,MARCH1,RGS10,RNASE1,LRRK2,RTN1,ASRGL1,MRAS,SLC1A3,YPEL4,CCDC88A,SLC37A2,TBL1X,KIAA0930,ARHGAP9,SLC44A1,TLR4,NPL,SSBP2,WIPF1,WNT7A,NLRP3" Coexpression M3601 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with antigen-B7-1. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "BRAP,ADRB2,AP1B1,MAP4K3,APP,CAMK2B,MAP7,ARHGEF25,CCKBR,USP2,EPS15L1,CLTB,NGEF,ABCG1,SDC3,ARMCX2,DCT,USP3,NR1D2,ABCC5,ING4,STX2,ERCC2,NSG2,GABBR1,INPP5K,RAPGEF4,COQ10A,KCNH1,KIT,LMO2,MATK,NAP1L2,SLC11A2,NTRK3,PDE1B,PKD1,PLTP,SPATA6,RETREG2,BSDC1,ZYG11B,RFX2,RPS6KA2,GALNT10,SOX11,ST5,SEMA4A,TCF7,ZBTB16" Coexpression M8163 Genes down-regulated in HEK293 cells expressing mutant NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ABCF1,ADARB2,ADCY8,AMPD2,LDLRAD4,SLC25A14,ARHGAP33,CLCN4,CSNK1E,CTIF,MAMLD1,E2F6,EN2,KIAA1109,GAB1,GAD1,RUNDC3A,LUZP2,GPER1,HSPA1L,C2orf72,KCNF1,MEF2C,MYL3,NINJ2,MAPK3,RAB3A,BEND5,RXRA,CPEB3,PPP4R3A,SLC22A4,USP33,SOX10,UNC5B,INKA2,SEPT8,VAMP1,SYN1,SYT1,DNMBP,AGTPBP1,AP4E1,ZNF106,AKTIP,NACC2,ZBTB14,UPF3A,MPPE1,ADAMTSL3" Coexpression M4221 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h versus the untreated cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "OSBPL1A,USP35,AMPH,UPRT,NRP2,NIPA1,CAMK2D,ZMYM4,LRWD1,CHN2,ZFYVE9,CLCN3,CTH,KIAA0513,MTX3,RCAN1,FAM13A,PHF20L1,ENPP6,DLC1,CAMSAP1,SUCO,FYN,NFU1,RAB30,ADGRA3,MIER3,DIPK1A,PLCL1,MBOAT7,POU3F2,EPDR1,NCR3LG1,PTPRE,ZYG11B,ZMAT4,SATB1,CNKSR2,SLC6A1,SP4,CAND2,UHRF1BP1L,C12orf76,DMXL2,CUX2,TPD52,TPM1,SSBP2,ZIC3,RNF146" Coexpression M5422 Genes up-regulated in comparison of eosinophils versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "OSBPL8,GAS7,MARCH3,MTMR3,LRRFIP1,DLGAP1,NMT2,CLOCK,PITPNM3,TBC1D5,DBT,NR1D2,DMTF1,EIF4G2,CHST15,FGR,UBE2E3,C1orf61,B3GAT1,USP19,LILRA2,GPR12,GRIA2,PRDM5,SCRG1,IL6R,INPP5B,KIF5A,KIT,MEIS2,NFE2L2,NME4,SPATA6,PPM1B,PTAFR,PTPRE,ROGDI,SMPD3,SUPT20H,FAM102A,RAB3GAP1,BTBD7,SLN,ERBIN,PDLIM2,KLHL4,HIF3A,THBS4,TLR4,SSPN" Coexpression M3731 Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ADCY8,OSBPL1A,ADAM23,CFLAR,ST3GAL5,OSGIN2,CALB1,CDC25B,DNAJB5,CSF3R,VCAN,INTS1,YTHDC1,ZEB2,SV2A,RCAN1,IGSF6,F3,PPP1R1B,GTF2IRD2,SUCO,TMEM175,INSM2,KCNMB4,CLASRP,SYNPO,HPCA,IRF8,NDP,NFIX,OLR1,PAH,PDE4B,PDGFRA,MAPKAP1,PPP2R2B,RALGDS,ROBO1,ELP2,RPS6KA2,SLC1A6,SLN,KIF13A,PALLD,DOK5,TAC1,FTSJ1,FRMD6,LAS1L,SPATA13" Coexpression M5571 Genes down-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "ADD1,NLGN4X,SEMA6A,APBA2,APP,ZSCAN18,ASTN1,ATM,ATP1A1,LDLRAD4,BTRC,CBFA2T2,CSNK1E,IPCEF1,CEP170,E2F6,IRAK4,BSCL2,EPB41L2,GPR153,SARAF,CPLX2,BACH2,LINC00667,IL6R,IL6ST,ZNF862,PLCL1,PMP2,POU6F1,LRRN3,FAM120C,RAP1GAP,ZCWPW1,TRIM46,SELL,CASC3,SH3BGR,SLC9A5,SMARCD3,CAND2,PEG10,LMO3,ST5,ACSL6,ICAM5,TLL2,TNS1,UGT8,CERS6" Coexpression M5022 Genes down-regulated in comparison of myeloid dendritic cells from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "AGT,AMT,PLA2G4C,CFLAR,BMP7,MAP7,COL4A5,NRG2,SNCAIP,PITPNM3,KIAA0040,SGSM2,DTNB,SEZ6L2,EDNRB,CNNM1,SRPK3,CEND1,TESK2,GNAL,GUCY1A2,HNF4G,RBPJ,IL12A,DIPK1A,KCNC1,KCNK1,KCNN1,LMO2,MYH7,NEFH,NODAL,DPY19L2P2,PDCD2,ENPP2,GPR173,POU3F2,DCHS2,RAD51D,TTLL7,RLBP1,RNASEL,CLIP1,SH3GL3,FUZ,ACSBG1,RUNDC3B,XRCC4,TUBA1A,PARP11" Coexpression M5009 Genes up-regulated in comparison of myeloid dendritic cells (mDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "KIAA1324,SEMA7A,APBB1,APOC2,CASK,ASTN1,ATP6V0A1,CDK5R1,WASF1,IL33,THSD7A,REPS2,CDC42,TAOK2,LHX2,SLC24A2,TPP1,ENTPD4,ATRNL1,SLITRK5,IP6K1,GSDME,DRD1,TUBD1,SEMA4D,TRAF3IP2,HIGD1B,NEU3,GPR162,PRRC2B,NR3C1,SYNPO,PMP2,PKIA,PTPN13,GAL3ST4,TCP11L1,SYBU,RCOR3,ZNF423,MCF2L2,INKA2,EXOC7,PCDHB6,ZMAT3,RPRM,UBTF,ZNF37BP,FXR1,RNF146" Coexpression M7306 Genes down-regulated in lymphocytes treated with TNF [GeneID=7124] for 2h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "CLK4,TMCC3,PHF12,PPFIA1,TNRC6C,ZFYVE28,ATM,ATP2B1,BACH1,CASTOR3,CCPG1,MS4A7,CNN3,PNPLA8,ZFYVE16,IST1,ZEB2,FRY,KMT5B,GOLGA7,PAN3,ZNF585B,PRKAG2,ZMAT1,ATP2B1-AS1,BTN2A1,GPR155,SSH1,ZNF655,PPP2R5C,SLC26A11,PTPRE,ZNF844,FAM161B,FBXO11,BTBD7,GKAP1,ABTB1,MYCBP2,KDM4C,ARHGAP26,ERBIN,ANKRD12,DNMBP,TCF7L2,ZNF189,ZFAND5,AMN1,NLRP3,RNF146" Coexpression M4514 Genes up-regulated in comparison of NK cells stimulated with IL2 [GeneID=3558] at 16 h versus NK cells stimulated with IL15 [GeneID=3600] at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "SYT13,SEMA7A,APP,ASGR1,KSR1,CBLN1,CLDN10,LDB2,CCKBR,DCLK1,CHGB,TAOK2,DGCR9,RBM39,CREB5,SEC14L5,DGKG,TIAM2,SGK2,ING4,WAC,STRADA,AGAP2,WASF3,GATM,GJB1,OS9,GNAO1,PSRC1,IL1RAPL1,ADAMTS6,CDH20,KCNB1,SCAMP5,BCO1,PCBP3,PDE1B,PTN,PTPRZ1,RIT2,PNMA8A,SCG5,SLC22A4,SOX1,KLHL4,PCDHGB6,PSD3,PCDHA6,TEK,VSNL1" Coexpression M8318 Genes up-regulated in NKT cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "PLA2G4C,ARSE,CADPS,RGS9,LHX2,CYBB,MED24,MRNIP,SRPK3,EN2,KAT8,FGFR1,USP19,LILRA2,GRIK3,CIT,KAT7,IRAK3,PADI2,MMP16,PCBP3,PAX6,PENK,HERC2P3,PLCD1,PLIN1,PLXNB3,POU6F1,MAPK3,RELN,PSD,PYGM,SCN7A,RASA3,SGK1,ERC1,FCHO1,ACSBG1,SYP,RALYL,CDH22,THRA,RBFOX2,TPM1,TPM2,ZMYND8,TSN,UCHL1,FLRT1,GDPD5" Coexpression M7550 Genes up-regulated in double positive thymocytes with ELK4 [GeneID=2005] knockout: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v6.0) 2.78E-04 1.00E+00 3.80E-03 3.77E-02 50 199 "SRPX,GPRASP2,ANK2,VAT1L,ARNTL,CADPS,LINC00847,CDK5R1,USP6,AKAP6,ABI3BP,CREM,SLC12A6,FSD1L,OPTN,EGR3,FGF1,AMOTL2,CAP2,ST6GALNAC3,NRG3,SYT17,GFRA1,GRB10,SCRG1,HMGCL,ARHGAP12,TAGLN3,NAP1L3,NCAM2,BCAS3,PTPRH,TUG1,KLHDC8A,SCN3A,SCG5,SH3BGR,WDR47,NAPB,LMBRD1,SPATA7,SST,PJA1,TRIM2,BEX4,TUBB2A,UCHL1,ZNF711,ZNF540,RNF103" Coexpression M2787 Genes up-regulated upon knockdown of PTEN [Gene ID=5728] by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 2.79E-04 1.00E+00 3.80E-03 3.77E-02 48 189 "KLRC4,ARHGDIG,ZBTB10,ADGRB2,BMP7,BMPR1B,C5,IL33,KALRN,NGB,P2RX6,LHX2,GAL3ST1,SPOCK2,DCC,LYPD1,PLPPR4,EDN1,EEF1A2,EFNB3,RASL12,FGF1,B3GAT1,GABRA5,GNAO1,GPER1,HPR,TUBB2B,MYBPC1,NAP1L3,PFKFB4,CDIP1,PTPRZ1,ACSS3,TMLHE,CCDC102B,SLC30A10,NTNG1,SLC6A1,DOK5,NFASC,CAMTA1,TMEM151B,PCDHA5,TGFBR3,SSBP2,UCHL1,GJC2" Coexpression 18338247-SuppTable3 Human Breast_Harvell08_298genes GeneSigDB 2.79E-04 1.00E+00 3.80E-03 3.77E-02 48 189 "ABAT,XKR4,AP2A1,BBOX1,APBB2,NUMB,SLC4A4,DST,CA12,CAMK2D,ZFP28,CX3CR1,MATR3,DSCAM,EPB41,OLFM1,SCARA3,SYNCRIP,PDLIM5,PHYHIPL,GART,GNG4,PRDM5,IFI16,KCNMA1,ARHGAP12,KITLG,MMP16,MYO5A,CLDN11,PDE3B,ENPP2,PFKFB3,ANKHD1,SALL1,SATB1,CPEB3,MCF2L2,LMO3,SYN2,TEX15,TMEM121,CABIN1,STXBP4,PPIL6,TTC3,ZNF711,PROCA1" Coexpression 15955831-SuppTable5 Human StemCell_Komor05_91genes GeneSigDB 2.80E-04 1.00E+00 3.81E-03 3.78E-02 26 84 "PLA2G4C,MYOM1,CD86,CSF2RA,CTIF,HEPH,MFAP3L,HSD17B14,EPS8,GP1BB,IGF1,IL6ST,KCNMA1,KIFC3,MSR1,GPR88,PBX1,SMOX,LRP12,SH3TC2,GALNT10,ITSN1,ACSBG1,SIN3B,PARD3,NT5M" Coexpression M7517 Genes up-regulated in the luminal A subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.80E-04 1.00E+00 3.81E-03 3.78E-02 26 84 "ATP1A2,ATRNL1,CHRDL1,LRRC17,ABCA8,FHL1,PNMA2,GFRA1,GPD1,HLF,IGF1,ITGA7,LAMA2,PCSK5,ENPP2,PLIN1,PTHLH,ELOVL2,PTN,RTN1,SPTAN1,PSD3,TIMP4,ZBTB16,LAMP5,MAP3K12" Coexpression M12707 "Transcripts enriched in pseudopodia of NIH/3T3 cells (fibroblast) in response to haptotactic migratory stimulus by fibronectin, FN1 [GeneID=2335]." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.80E-04 1.00E+00 3.81E-03 3.78E-02 110 518 "BEND6,PPFIA1,PKP4,APC,TMEM263,ARHGAP5,RGS20,DOCK11,DCAF5,NAE1,CAMK2D,CCNH,SEPT7,DCLK1,CFL2,SRSF11,QKI,NIPBL,PCYT1B,BTF3L4,ACBD5,CLOCK,NCOR1,CSNK1G3,UBXN2A,FGFR1OP2,MATR3,YTHDC1,MYEF2,DLG3,DTNA,DNM1L,EDN3,YAF2,SH3GLB1,MBNL2,ABI2,EIF4G2,ACSL4,VTI1B,USP16,MSANTD4,STAG2,ZMYND11,STARD10,KIAA1841,TUBGCP4,HTATSF1,STON1,NR3C1,ATE1,AP4S1,PSIP1,HNRNPK,AGFG1,SMAP1,IFI16,C5orf24,HES5,INPP1,KIF2A,LIMS1,MBNL1,MYO5A,NAP1L1,NFIA,DDR2,OPA1,OLA1,PIK3C2A,PPP3CA,MAPK8,OXR1,RBBP8,PBRM1,TMLHE,RPS20,SCP2,TRA2B,FNDC3A,GKAP1,MAPKBP1,PALLD,RBM34,IQSEC2,TROVE2,ERBIN,NXT2,VPS13A,TAF9,CAMSAP2,AGTPBP1,TCEA1,TCF12,ITGB3BP,ACTR6,BHLHB9,R3HDM1,TPD52,C9orf85,PDSS1,TBC1D15,XPO1,ZNF24,MFF,CAB39L,MRPL47,HNRNPA3,RSPRY1,FXR1" Coexpression 17571080-SuppTable2a Human Leukemia_Sun07_407genes GeneSigDB 2.86E-04 1.00E+00 3.88E-03 3.85E-02 76 334 "ADORA2A,ADRB2,PARG,AQP4,TMEFF1,RGS20,CACNA1E,CBLN1,CCK,SYNGR3,DCLK1,CHN2,COL4A5,ABCG1,RGS6,VCAN,PDE4DIP,ST18,CX3CR1,RIPOR2,TOX,DMD,MAMLD1,E2F5,ANKRD46,EML1,LRRC17,ERBB4,REEP2,FGFR1,HPGDS,GPM6A,LILRA1,GPR19,PCLO,PTPRT,IGFBP1,JAK1,KCNN3,KCNQ3,LIFR,MEIS1,MEST,MPP2,MYO6,NCAM2,NELL1,NFIX,PDE4B,PDYN,PHKG1,PMP22,MAPK4,MAPK10,KLK6,PTPRB,PTPRO,ERI2,SHMT2,SLC12A2,SLCO1A2,SNRPN,PDZD2,STXBP1,WSCD1,TF,LEFTY2,THBS4,TIAM1,DAAM2,TRH,WRN,SLC13A3,SF1,ZIC1,AP3B2" Coexpression 19933690-TableS1 Human Endometrial_Altmae09_145genes GeneSigDB 2.91E-04 1.00E+00 3.94E-03 3.91E-02 31 107 "ADRB2,SLC24A4,NR0B1,LRRC4C,PDE8B,ATP1A2,TMEM130,CCDC3,KBTBD11,EDN3,LRRC17,B3GAT1,GLRB,STMN2,PTPRT,HBA1,HP,DUSP26,PRRX1,PRKCG,VEPH1,TMEM100,LRFN5,ELMOD1,FAM81A,PKNOX2,CXXC4,TRH,TRPC3,TTTY15,ZNF711" Coexpression M1204 Cluster 8: genes showing sustained pattern of down-regulation after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.91E-04 1.00E+00 3.94E-03 3.92E-02 6 8 "KIAA0753,MAPT,NRCAM,NRGN,SERPINI1,SPP1" Coexpression M3961 Genes with GO annotation and up-regulated after DNA damage in cell lines from young donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.01E-04 1.00E+00 4.06E-03 4.03E-02 55 225 "ATP6V0A1,BCL2L2,NRP2,LDHD,CACNA1I,LRBA,AKAP6,NCOR1,PDE4DIP,CTNND1,CYBB,DBT,DCT,ARNT2,DOCK2,EFNB3,EGFR,ERBB2,FOLH1,GABBR1,CHL1,GALC,ATF7,EML4,HNMT,HPCA,HSF2,IGFBP1,ITIH2,ITPKB,KCNK1,LIG4,LMO2,ADAM11,MEF2C,MITF,NRCAM,PCSK5,PDCD2,PLCL1,PPP3CA,MTMR10,PTPRN2,RBBP6,RIT2,SLC1A3,SLC6A1,TAL1,TIE1,KAT6B,USP1,SLC26A10,SYNC,DNALI1,SOCS4" Coexpression 17673513-TableS1 Mouse Testicular_Cederroth07_170genes GeneSigDB 3.10E-04 1.00E+00 4.06E-03 4.03E-02 27 89 "ADGRF5,AMPD3,MYOM2,DCLK1,COL9A1,FEZ1,ARHGEF10,SLITRK5,GREB1,FLT1,HIGD1B,DNER,KCNMB4,GRM7,IGF1,KCNK1,MEF2C,MID1,PRRX1,PTPRB,TMEM100,SPHKAP,SOX5,HIF3A,ZMYND8,TTC3,VLDLR" Coexpression M17026 Genes up-regulated in three-dimentional (3D) cultures of preinvasive (S3-C) vs invasive (T4-2) breast cancer cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.11E-04 1.00E+00 4.06E-03 4.03E-02 52 210 "AMT,APC,ASGR1,ATP2A2,NAE1,C5,CDK5R2,CAPN3,RUNX1T1,KYAT1,CCK,DCLK1,ADGRG1,TAOK2,EPS15L1,RAB33A,STOML1,FAM189A2,AKAP5,CSF1,DCTN1,DMD,DNM2,HIPK3,CDKL3,ZMYND10,FGF12,FGFR1,GRIK1,GRIN1,WIF1,INPP1,MMP17,MT3,PTAFR,PTK2,PTN,QDPR,RFX3,RYR3,CASC3,SST,TAC1,TCF12,GPR161,LILRA4,CHST5,SSBP2,TMEFF2,ZNF32,FTSJ1,ST7" Coexpression 20194811-Figure1c Human Lung_not_cancer_Lockstone10_51genes GeneSigDB 3.14E-04 1.00E+00 4.06E-03 4.03E-02 16 42 "ZNF608,CDC42BPA,MPDZ,FRY,EFCAB2,ZNF512,ADGRA3,KLHL23,PRKAB2,HKR1,TTLL7,SEC61A2,SOX5,ADHFE1,SYNE1,STXBP4" Coexpression M1347 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 6 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.14E-04 1.00E+00 4.06E-03 4.03E-02 109 514 "KDM5D,TAOK1,SYT13,PKP4,APP,SHTN1,ARHGDIA,BCL7A,SCAPER,CANX,LDB2,ARHGEF2,SEPT7,FOXN3,KMT2C,CLTC,TJP2,MAGED1,NCOR1,TENM4,PLCXD3,PUM1,FGFR1OP2,HDAC4,ZEB2,DPYSL2,APH1A,ING4,DCTN4,WAC,TBC1D16,FLNC,KHDRBS3,CSPG5,ZNF274,SEPT9,TNRC6A,GPD2,EML4,GRIA4,ZHX1,ELOVL5,HMGB1,HMGCR,C5orf24,KCNK1,KIF2A,MDFI,MIA2,MOV10,SAMD5,SESN3,PTOV1,NASP,NFIA,NFIX,NFYA,PDE3A,CDK14,NLGN3,SSH1,PKM,PCDH18,STRN3,RC3H2,PRRX1,PPP2R5E,KANSL1,GON4L,QRICH1,PTPRD,PTPRZ1,PEX5,FAT4,BSDC1,ROBO1,EMID1,SFPQ,CHD9,DZIP1,PPP4R3A,SLC8A1,CDK5RAP2,PALLD,SOX11,EMC1,ZC3H13,ST5,MPRIP,PRRC2C,C3orf70,PLCB1,SYN1,WWC1,SMG6,SIN3B,FRYL,AKTIP,TIAM1,RBFOX2,TPM3,METTL3,TRPS1,ZMYND8,CLDND1,ZBTB14,WNK1,STOX2,VANGL2" Coexpression M4677 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ACTN1,KLHL32,RNF157,MTA3,C1QTNF3,ZSCAN18,NUMB,ZNF582,FOXN3,ARMCX2,MRNIP,BSCL2,C8orf37,NBEA,ZNF512,RAB30,ADGRA3,PRRC2B,LINC01550,HSF2,ITPKB,KCNA6,MYO9A,ZC3H12B,IDNK,PC,FAM216A,PLCL1,DRAM2,VPS13C,PTK2,FAM120C,ZNF844,RAB3A,RFX5,RMI1,CNKSR2,PAAF1,KDM4C,PBLD,SMOC1,BHLHB9,NR2C2,TSC1,SSBP2,FRRS1L,PRDM10,SNX27,FAM13C,LAS1L" Coexpression M5390 Genes down-regulated in comparison of dendritic cells (DC) stimulatd with LPS (TLR4 agonist) at 48 h versus macrophages stimulated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ADRB2,AMPH,PPFIA2,NUMB,HCN2,PRC1,LRBA,TPP1,CHD5,VCAN,ERC2,CYBB,DUSP9,SEZ6L2,EDN1,SRPK3,EPHA5,FCGR1A,ERGIC3,TRAF3IP2,SEPT9,GCNT2,RND1,VSIG4,KCNJ5,LSS,MARK1,MSR1,MSRA,NDP,OCRL,OPCML,P2RX7,PFKFB3,KCTD15,ZNF426,SYTL2,RAP1GDS1,GAL3ST4,MCMBP,ASRGL1,SCMH1,SLN,SPP1,SSTR2,KLHL7,SIK3,TGFBR3,UBE2H,LAT2" Coexpression M8337 Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells (Tfh) versus all Tfh. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "KIDINS220,CDC42BPA,EIF4G3,C5,USP2,INA,CLCN3,KIAA1549L,SLC4A7,SUSD5,DZIP3,DCAF4,BRINP1,DNAH9,MBNL2,ERBB4,EXTL2,ZMYND10,DPYSL4,RUNDC3A,LILRA1,PCLO,GRIN1,GRM8,GUCY1A2,HPCA,KCNA6,MID1,PCSK5,ST8SIA5,LRRN3,PTPRE,PTPRO,SELL,ST6GAL1,CNKSR2,SLA,SLC6A1,SLC6A11,SLC22A4,SMARCC2,PALLD,PDZD2,EPB41L3,ARHGEF9,TAF9,RBFOX2,SLC26A10,SLC17A7,FAM182B" Coexpression M9889 Genes up-regulated in colonic lamina propria cells sorted by CXCR6 [GeneID=10663]: high versus low. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ARNTL,SYNJ1,ARHGEF7,FUBP1,CACNA1I,ASIC3,IQCK,SLC4A7,ENTPD4,CST3,GPRASP1,DCAF8,SV2A,SGSM2,RASGRP1,PHF20L1,GOLGA7,ENO2,ANKFY1,TRMO,RAPGEF6,GFER,MSL3,GOLGB1,EML4,KLF12,IL6ST,IL11RA,KLC1,SLC11A2,QRICH1,PTPN13,PLEKHB2,ATG16L1,SUSD4,SEC61A2,ALG9,ATXN7,SCN2B,RUFY2,ELMO2,RCOR3,ANKRD36,DOP1A,TNIK,KIF21B,VPS13A,PLPPR2,CLDND1,KAT6A" Coexpression M9763 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ARID1A,AP2A2,SPOP,CARNS1,TNRC6C,CDC14B,BACH1,ARHGEF1,C1orf52,CNN3,COL9A3,ACBD5,ZFP28,CLOCK,ERC2,EDRF1,GPRASP1,IP6K1,DNM2,TOM1,RASGRP1,LRRC23,SEZ6,FCGRT,FGF13,WASHC2A,MITF,PBX1,PDE1B,SERPINI1,PLEC,POLG,SIDT1,RIPOR1,RAP1GDS1,TMLHE,SCG5,USP33,KIF21B,KDM3A,ITPRID2,TTBK2,FRYL,TRIO,TBC1D15,PARP6,KCNAB1,MPPE1,RNF146,SENP7" Coexpression M9198 Genes up-regulated in T reg: induced versus total. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "AS3MT,TMCC3,SLC12A5,ALAD,GPRASP2,PDXK,ALDH7A1,BACH1,FMNL3,ZMYM4,ZBED5,ARHGEF6,CSNK1E,GREB1,GPRASP1,TOX,DAPK1,ARMCX2,PIPOX,ARMCX1,PRMT5,IQCG,TACC2,CHL1,GALC,SPIN1,KCNMB4,GPD2,TOX2,ACOT7,ADAM11,TM6SF1,AFDN,PTOV1,MAPK7,SYTL2,GTDC1,ATXN1,ZNF821,SH3BP2,CAND2,NSFL1C,SLC37A2,USP22,TIAM1,BHLHB9,TP53BP1,TRIO,RPL7L1,ZNF32" Coexpression M7157 Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 12h. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ESYT2,DGKZ,SFMBT2,GPR146,BAIAP3,PPT2,HDAC4,KBTBD11,DLG4,PDCD6IP,EXTL2,POLR1B,FGF13,EVL,ERAP1,SEPT9,KCNMB4,PADI2,ZDHHC15,IL6R,IL6ST,ITPKB,JAK1,SLC35G1,KIF2A,STXBP5,MBNL1,MBP,SRSF12,SLC11A2,SETD4,P2RX7,TMIE,PRKACB,SYTL2,EML5,CEP97,RGS3,RNASEL,TMLHE,ATP8B4,CLIP1,SCP2,GALNT10,TNIK,ACSBG1,PIK3R5,RUNDC3B,SSBP2,SPATA13" Coexpression M8205 Genes up-regulated in macrophages: tumoricidal versus control. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "NDRG3,LTBP4,GPAM,SLC4A4,ATP2A2,ALDH7A1,BCL2L2,CCK,P2RX6,CFL2,RAB28,CNN3,SLC32A1,FEZ2,DCTN1,SEC16A,ANKRD46,C8orf37,DMTN,ETV1,EYA1,TUBB4A,ST3GAL6,PCYOX1,FOXO3,JKAMP,GAB1,NCKAP1,GHR,GLRB,FICD,CCDC80,PTOV1,NDUFA5,PENK,PGAM2,SCHIP1,SLC25A36,ZC3H14,SLC6A8,SLC12A4,GKAP1,KDM3A,TBCEL,HEY1,CA14,UBE2H,ZNF23,NAV2,DPF3" Coexpression M8853 Genes up-regulated in lymphoid primed multipotent progenitors versus common lymphoid progenitors. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ANK3,AQP4,ST3GAL5,BSN,SEPT7,CNN3,BTF3L4,HAPLN1,AATK,RGS6,PDE4DIP,DDX46,DLG3,RASGRP1,EPB41L2,FGF1,AMOTL2,SYT3,COQ5,GGT5,DHRS4,GRIA4,HPCA,IL11RA,KCNN1,MDM4,MMP17,MTR,MYH3,NPTX2,NUCB1,PDGFRA,PPP5C,RASGRF1,ZDHHC14,ERI2,ATXN1,HSPA4L,SHMT2,FHOD3,SLC1A2,CMTR2,KLHL7,SYT11,TBCEL,ZFPM2,THRA,TRH,CA14,WNK1" Coexpression M9408 Genes down-regulated in CD8A [GeneID=935] dendritic cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "RALGAPA1,ACTN1,AMPD2,ANXA7,APP,MAP4K4,AKAP12,LRIG1,ZFYVE16,ARMCX2,SV2A,ST3GAL6,CHST15,FOXO3,FYN,TRAF3IP2,IQGAP2,GLS,STARD3,OS9,LILRA2,NR3C1,GSN,GUCY1A1,LMO2,SMAD1,MEF2C,AFF1,MXI1,NFYA,PDE4B,SERPINI1,RETREG1,PPP3CC,PTPRE,PCMTD2,SATB1,SLC2A5,TMCC1,MAPK8IP3,RGL1,SYT11,DMXL2,WASHC4,PSD3,AHCYL2,BEX4,VAV1,ATP6V0E2,CERS6" Coexpression M3156 Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "SYS1,AMPD3,PARG,ZFYVE28,ARHGAP5,CAMK2B,SEPT7,CDO1,VCAN,ZFYVE16,HP1BP3,MED24,ASB3,EVL,TUBGCP4,KIAA1958,CNTRL,PSIP1,MAN1B1,DIPK1A,GATD1,KLC1,MARK3,MEST,AFF1,CCSER2,EPN1,SLC26A11,GRAMD1C,ANKHD1,ARID4A,PBRM1,RNASEL,FAM102A,SLC1A3,SMTN,EPC1,TMCC1,WDTC1,FCHO1,MPRIP,ATP11A,SMG6,MGRN1,UBE2H,WIPF1,SF1,ZNF708,RSPRY1,SENP7" Coexpression M9608 Genes up-regulated in CD42 low [GeneID=100133941] cells from thymus: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "SPARCL1,ADGRB1,MYOM2,MAP4K4,HOMER3,COL9A2,FEZ2,GPSM1,DBT,PITPNC1,YTHDC1,ATN1,RCAN1,AGAP3,CINP,SMC2,GART,TUBGCP4,SRCAP,GFER,GP1BB,CLASRP,GSTM5,KCNK2,LSS,HCN1,CLDN11,PALM,ENPP2,MAPK7,SNRK,ELP2,RPS6KA2,KIF16B,FHOD3,DBNDD2,TAB2,GANAB,KLHL7,JMJD6,SYPL1,TAC1,TACR1,NSD1,DICER1,NTSR2,VAV1,LAT2,WRN,WNK1" Coexpression M7508 Genes down-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) versus non-Tfh. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "BCAR3,SYT13,VAT1L,DNAH17,LONRF2,CHRM1,ZFP28,CLIP3,LRRC3B,PHACTR3,PABPC5,HS3ST2,NYAP1,EPB41L1,CDKL3,CORO2B,TPK1,GCNT2,GPR75,MAP7D2,GPT2,KLF12,HSPA1L,CDH20,KCNB1,SHC3,NELL1,HCN1,DDR2,KCTD15,HMGCLL1,NECAB2,MAPK10,FAM184A,RNASE1,SYNDIG1,ASIC4,SH3GL3,URGCP,SCN3B,SMOC1,ARHGEF9,TEX15,DNAH7,RGMB,TRH,PPIL6,RBFOX3,MDH1B,ST8SIA2" Coexpression M3757 Genes down-regulated in comparison of control dendritic cells (DC) at 1 h versus those stimulated with CpG DNA (TLR9 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "SERPINA3,SLC25A25,DSCAML1,HHATL,ADRA1B,ADRB2,AGT,SPTBN4,RGS20,HCN2,ENTPD4,SLC32A1,CSNK1E,FAM131B,DSCAM,DTNB,EBI3,MRNIP,DMTN,ERBB4,SCML2,ARFGAP2,MTHFD2,ADGRA3,HLF,INPP1,KCNJ4,KIFC3,MTTP,HS6ST3,MYCN,NEFH,PDGFRA,PCDH18,PTAFR,ROBO1,CLIP1,TRA2B,ZFP30,FAM81A,SLC6A1,KIF13A,SAMSN1,APOM,PHLDB1,CNTN2,ZFPM2,NTSR2,LGI4,EMSY" Coexpression M4886 Genes up-regulated in comparison of follicular B cells versus late germinal center (GC) B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "PLA2G6,ADGRF5,ATP6V0A1,CDK5R1,CACNA2D1,FAM19A5,C4orf33,CNN3,AKAP6,CLOCK,HDAC9,IST1,SNX29,ELN,KCNMB2,CHST15,FGR,POMT1,ATP6V1H,ZMAT1,GHDC,PPARGC1A,TNRC6A,ZNF638,STON1,LINGO1,ATOH8,CELF3,WIF1,NXPH3,TLX1,CELF5,PAK3,SERPINE2,FAT3,RPE65,RYR3,DOCK10,CHD9,PKNOX2,LHPP,STAC2,PHLDB1,VAMP1,VWC2,TCF4,ZFPM2,TPD52,SPIRE1,CAB39L" Coexpression M9447 Genes up-regulated in splenocytes: control versus infected with Baki-1 MuLV virus. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "BRAP,PWWP2A,MTA3,MAP4K3,STX16,DOCK11,CAST,CBFA2T2,CRLF1,CNOT8,IPCEF1,SIPA1L1,UBXN2A,CYBB,FGFR1OP2,ARHGAP24,PITPNC1,EIF1,RCSD1,TAOK3,AK8,FAM49B,SARAF,FYN,CAB39,ZMYND11,INPP5K,RAB30,COQ10A,IL6R,IL6ST,SESN3,MYO6,NCF2,P2RX7,STRN3,PPP3CA,BCAS3,TUG1,PLEKHB2,BSDC1,MYO18A,CPEB4,ZBTB43,TAB2,DICER1,TSC1,SF1,TUBA1A,TTC7A" Coexpression M5821 Genes up-regulated in comparison of naive CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ACADM,CLK4,ADD1,BRAP,ADRB2,API5,LRWD1,CNN3,FAM107B,FARSB,ABCC5,MRPL37,ATP8A1,JKAMP,ARFGAP2,NSG2,GABBR1,HBS1L,SRCAP,SESN1,GGT5,TXNL4A,RNPS1,GSN,GSTT2,ELOVL5,MAT2A,MBP,GIT1,PIK3CD,PKD1,PRKCB,CYBC1,PSMD13,EML5,RAD17,RGS10,RPRD1A,CLIP1,SATB1,SELL,GALNT10,SGK1,FAM102A,ST6GAL1,INTS9,SS18,SEMA4A,TBCEL,MTCH1" Coexpression M7212 Genes down-regulated in mouse embryonic fibroblasts (MEF): control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ACTN2,BCAR3,FGD2,ARMC12,GAS7,TNRC6C,CASK,BTK,SGCE,HIP1R,CBS,SLC16A4,NDST3,CPNE6,CNN3,SH2B1,RGS6,MAGI2,SEC16A,EBF1,RASA4,ERBB2,DNAJC27,SESN1,GHR,RUNDC3A,GRIA1,GRIK3,CIT,TLX1,HSD17B1,MYLK2,KCNB1,KCNMA1,LIFR,C2orf80,SMAD9,TREM2,WBP1L,ZDHHC14,KLHL11,SELL,SH3BP2,CPEB3,DZIP1,SCN3B,BEX1,SEMA4A,ITGB3BP,CFAP298" Coexpression M3422 Genes down-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus regulatory T cell (Treg) from wild type animals. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "AS3MT,NDRG2,ZNF608,TBC1D14,WDR35,ALCAM,GPRASP2,PHYHD1,BCAS1,ZNF583,RGS9,ST3GAL5,CAPN3,CD38,CD81,OSBPL3,HDAC9,ARMCX4,SRGAP3,SLC9B2,SESN1,MMADHC,ADAMTS6,ICA1,TUBB2B,L1CAM,PPM1L,PTOV1,NAP1L3,NCF2,PENK,SERPINE2,SMOX,PPM1B,PRR5L,WLS,MAPK12,ITSN1,MAGI3,ANKRD6,TAB2,DNAJC9,TCF4,TF,STXBP4,TMEFF2,DNAJC12,NSD2,ATP6V0E2,TMEM237" Coexpression M3165 Genes down-regulated in comparison of Th2 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "SLITRK1,MTA3,TBC1D14,PPFIA1,STOML1,NIPBL,CLOCK,RNF14,LRIG1,PITPNC1,DDX46,RBM12,F3,FECH,EVL,MPP6,TRAF3IP2,B4GALNT1,STARD10,RUNDC3A,TUBB2B,KIF2A,TTYH2,N6AMT1,PDE3B,GNG2,OLA1,PMS2,DEF8,PTHLH,RAB5B,RGS12,KCTD17,RIC8B,PRCD,CASC3,SMARCC2,ZC4H2,SYT11,CAMSAP2,TCF4,DICER1,R3HDM1,ZBTB14,ZNF23,SLC26A10,GDPD5,PCBP4,RGS7BP,FRMD6" Coexpression M5819 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "CLK4,ACTN1,ADCY6,AMPD3,MAP4K3,APP,CASK,ARRB1,MAP7,CNN3,ABCG1,ARMCX2,ABCC5,PLEKHA1,RACK1,POLR1B,CAMSAP1,EVL,NOP56,NSG2,SESN1,ZNF638,GSN,IL6R,IL6ST,ITPKB,KIT,SMAD1,PTOV1,SLC11A2,PKD1,RETREG1,EML5,RGS10,SATB1,SELL,FAM102A,ST6GAL1,DHX30,MYCBP2,TBCEL,TCF4,TCF7,ZEB1,SLC44A1,TNNT1,SSBP2,TTC3,RPL7L1,PHTF2" Coexpression M6774 Genes down-regulated in splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "DGCR6,PNMA8B,AP1B1,MTUS1,CDK13,ASCL1,RASL11B,ARHGEF1,SCARB1,ENTPD6,LRWD1,FOXN3,SLIT2,SEC14L5,RASSF2,TOMM20,IP6K1,ARMCX2,MED24,SACS,HSD17B14,MRPL37,HPCAL4,FYN,GAA,GABRG2,GJB1,GPM6A,RAPGEF1,RFFL,GATD1,ALDH1L2,NFYA,PBX1,PKD1,TTC13,BEND5,REV3L,RNF220,SHMT2,FHOD3,DHX30,SMARCC2,RBM34,TACC1,PCDHB7,ZNF346,REEP1,RNF103,NAV3" Coexpression M8486 Genes down-regulated in B16 melanoma (day 3): untreated versus adoptive transfer therapy. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "DGKD,BCAS1,MADD,CADM3,BACH1,DDR1,B4GALT6,IFFO1,CSF1R,PDE4DIP,CTNND2,NR1D2,DSCAM,SIDT2,NCALD,IGSF6,TMEM74,ZMAT1,B4GALNT1,SESN1,RAPGEF1,GSN,FRMD5,ACOT7,IL6R,L1CAM,SMAD1,GPR155,MAN2A2,AFDN,SERPINI1,PRKCB,PTCH1,PTPRO,RGS3,RGS12,RNASEL,RTN1,CCDC112,DOCK10,CHD9,SLC12A2,MYCBP2,EPB41L3,SLC44A1,DDHD1,SPIRE1,EVI5,CERS6,JMJD1C" Coexpression M7417 Genes up-regulated in immature neuron cell line: control versus interferon alpha (6h). MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "SDE2,GRAMD1B,OSBPL8,GPRASP2,APC,RGS20,NCOA1,DCLK1,FOXN3,ZBED5,EPS15L1,ARHGEF6,CP,KIF26A,PITPNC1,SACS,RABGAP1L,ANKRD46,YAF2,TMEM74,EXTL2,CHST15,FCGR3A,ATP8A2,LRRC75A,INPP5B,JAK2,AFF1,MOG,CTNNA3,NODAL,TRHDE,TTLL7,SLC25A36,RPRD1A,ROBO2,FNIP1,PPM1E,SHC4,YPEL4,PDZRN3,DOP1A,SYT5,LEFTY2,TTC3,TMEM237,ZNF189,SLC30A4,MFF,RNF170" Coexpression M4558 Genes down-regulated in comparison of DN2 thymocytes versus DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ACTN1,ADCY6,SORCS2,C1QTNF1,FAM131A,N4BP2L1,CCPG1,CHD1L,AKAP12,DAPK1,DLG3,USP3,RPS6KL1,SIDT2,NSG2,ARPP21,GFRA1,RAPGEF4,FICD,ATOH8,KCNH2,MARK3,MBP,TM6SF1,MIA2,PDPK1,RC3H2,SPATA6,SH3KBP1,PPP2R5C,PRKCB,RGS10,ARHGEF10L,SATB1,TRIM46,SCAF8,CPEB4,KDM4B,KDM3A,KDM4C,SLC37A2,TCF12,ARHGAP9,AHCYL2,ZMAT3,PRRT1,IL34,SLAIN1,PMEPA1,PLD4" Coexpression M4585 Genes down-regulated in comparison of adult DN3 thymocytes versus fetal DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ADRB2,AMPH,KCNAB2,CASK,ARNTL,BID,CA8,CAPN3,CBLN1,LY86,TBPL1,CTNND2,ELAVL4,PLEKHO1,CLVS1,RACK1,FDFT1,SCARA3,PDLIM5,GPR34,GRB10,FICD,AGFG1,ITGAV,KIFC3,LYPLAL1,MEIS1,MMP17,SETD4,PGAM2,SEPT4,PKIA,APTX,SIDT1,SNRK,PTPN13,PTPRO,SUSD4,CRTAC1,HUNK,RYR1,SOX6,SH3GL3,CDK5RAP2,KLHL7,CUX2,TJP1,BEX4,TNNT1,PCBP4" Coexpression M9420 Genes up-regulated in DN3 thymocytes: wildtype versus TCF7 [GeneID=6932] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "APBB2,GAS7,ADAM23,ST3GAL5,MTMR3,WASF1,CD38,MAGI1,RNF14,ABCG1,RGS6,CSNK1E,ARHGAP32,RIPOR2,RIMS3,DAPK1,ZEB2,MAGI2,RHOBTB1,ABI1,OPTN,SH3GLB1,EIF1,CHST15,HBS1L,IQGAP2,GLS,GPM6A,RASSF8,AGFG1,SMAD1,MXI1,ZNF862,NPTX1,PRKCB,PTPRE,RFX5,RPS6KA2,BTBD3,SNAP25,CAND2,KDM4C,DNMBP,IQCE,WASHC4,DOCK9,GORASP1,ZNF32,EVI5,NUP214" Coexpression M6570 Genes down-regulated in monocyte-derived dendritic cells: AM580 [PubChem=2126] versus rosiglitazone and AM580 [PubChem=77999;2126]. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "TKTL1,ADCY6,ADD1,BEND6,PHYHD1,ATP1B3,CFLAR,ARHGEF1,RCBTB2,PITPNC1,USP3,RASGRP2,ST3GAL6,FCGRT,TACC2,HVCN1,B4GALNT1,RAPGEF6,ZNF274,GPR34,STMN2,SPACA9,IRAK3,DDX19B,DIPK1A,L1CAM,MATN2,FXYD7,SFR1,SERPINI1,PIK3R1,SYTL2,SIDT1,ATP8B4,DGLUCY,GALNT10,RASA3,DOCK10,CABCOCO1,IZUMO4,KIF1B,RAP1GAP2,STX1A,ACSBG1,ARHGAP9,RELL2,LRRC8A,PIK3R5,SHD,FRMD6" Coexpression M9205 Genes up-regulated in CD8 T cells: wildtype versus STAT1 [GeneID=6772] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "AS3MT,ACTN1,ADCY6,TMCC3,ADD1,ESYT2,TBC1D14,GPRASP2,DGKD,ZFYVE28,NCOA1,DOCK11,FMNL3,LRBA,ARHGAP33,SLC25A27,ARHGEF10,SIPA1L1,KIAA0040,RIPOR2,DAPK1,DLG3,NYAP1,FRY,EIF1,F8,ARMCX1,RAPGEF4,BACH2,ZDHHC15,NIM1K,KCNH2,MX1,PIK3C2A,TMIE,LRP12,PRKCB,MAPK7,SYTL2,CEP97,SATB1,RASA3,DZIP1,TMCC1,TNIK,POGZ,FAM168A,WBP2,TUBB2A,VANGL2" Coexpression M3760 Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with CpG DNA (TLR9 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "KIAA1324,BCL2L2,ST3GAL5,CACNA1A,CACNA1B,MTMR7,NEURL1,DNAJB5,FHL5,IGDCC3,DLG2,DYNC1I1,EGFR,IGSF6,F3,DLC1,FER,SUCO,PDLIM5,MTHFD2,STARD10,RUNDC3A,GK,GRID1,HPCA,JAK2,KCNK2,CD200,HS6ST3,OPRL1,SNX10,POU6F1,PRKCZ,MAPK8,PSMA6,PTPRE,RAB5B,TMEM100,SH3BGR,NTNG1,CDK5RAP2,LHPP,SAMSN1,FBXW11,SLC44A1,MTMR14,DDHD1,TNFRSF1B,UGT8,VAV1" Coexpression M4672 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "TMCC3,AXIN2,TRMT9B,ZFAT,BRSK2,FAM189A2,CRMP1,CSNK1G3,ATRNL1,SEC14L5,RIPOR2,YTHDC1,DNAJC6,CHRDL1,NYAP1,ABI2,ELAVL2,RASGRP2,UBE2E3,CAMKK2,ARFIP1,GFER,GLS,RFFL,KIF3A,MUM1,GABARAPL2,INPP5B,KCND3,STMN1,GPSM2,FTO,SLC25A23,PSAT1,MTMR10,RPE,CCDC112,TMCC1,CAND2,ERBIN,TTBK2,SULF2,RHBDL3,RGMB,TRPC3,PPIL6,UPF3A,PARP11,CERS6,FRMD6" Coexpression M5585 Genes down-regulated in comparison of central memory CD4 [GeneID=920] T cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "DGKD,ATP1A3,BTK,LDB2,CD38,ADGRG1,FBXO7,MAGED1,CRY2,RNF14,AATK,CSF1R,FEZ1,ZNF804A,ELMO1,ACOT8,DNAJB6,TLR7,ADGRV1,CHST15,RASL10A,B3GAT1,GABRG2,ADGRA3,GSN,IRF8,JAK1,TM6SF1,MKLN1,NCAM1,PTPRE,ZDHHC4,RGS3,NUDT11,DGLUCY,GALNT10,URGCP,PALLD,MYT1L,KIF21B,ARHGAP26,SYT11,KLHL4,USP22,TGFBR3,NPL,TST,LAT2,ZNF74,ZNF142" Coexpression M3257 Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 3 h with YF17D vaccine. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ACADM,SPOP,ANK1,CDK13,CAPRIN2,CAST,LRBA,RCBTB2,ARHGEF6,AKAP7,SEC31B,CX3CR1,MATR3,FBXL5,SGSM2,CASP8AP2,ACOT8,ABCC5,SNX29,SIDT2,BSCL2,AMZ2,NELFCD,LILRA1,MAN2A2,PCSK5,RETREG2,PPP2R5E,CYBC1,SLC25A36,RXRA,AP1AR,SMARCC2,TEX2,ERBIN,CEP68,TTBK2,POPDC3,SIN3B,TCF12,DOCK9,ZNF106,CABIN1,TPD52,METTL3,ZBTB16,ZNF177,TUBA1A,PDSS2,UBE3B" Coexpression M4845 Genes down-regulated in comparison of CD8 T cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "DPF1,ADORA3,CHRD,TTLL9,CARS,NECTIN3,FAM169A,UBXN2A,CTH,USP6NL,TCAF1,MYEF2,AK5,DNM1,MRO,EN2,TMEM132C,FDFT1,USP21,NRG3,JPH4,GATM,ALDH1L1,LOXL3,CECR2,CELF3,NXPH3,HP,TJAP1,ITIH2,MTR,PNMA3,PPP1R1A,PRKCG,ZDHHC14,GAL3ST4,EPN2,CPEB4,HECW1,ZFR2,RHBDL3,PCDHB7,ICAM5,PARD3,SEZ6L,SYNPO2,PRMT8,SGK3,PLPP4,NAV3" Coexpression M4994 Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "OSBPL8,APAF1,KIF1A,CDK5R1,BTK,MYOM2,CDC25B,IFFO1,PREPL,DCAF4,IP6K1,EIF5,GMPR2,OLFM1,NOP56,PDLIM5,CAB39,CBX1,ARHGAP19,SYNPO,TJAP1,IPO5,MBP,MEIS1,AFDN,FAM216A,PPP2R5E,RFX2,KLHL11,CCDC25,RPL15,RXRA,ATXN1,TRA2B,SLA,SMARCC2,USP33,SPATA7,ELOVL4,SEPT8,SYNE2,MMS19,SATB2,ZNF106,SEZ6L,LAT2,ZFAND5,ZNF225,EPM2A,DPF3" Coexpression M4326 Genes down-regulated in comparison of TconvLP versus Homeo Foxp3- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "DPF1,AMPD3,API5,DYNLL1,BMP7,CA12,CD81,JAM2,LHX2,IGLON5,ZNF385A,CSF1,ERC2,NRSN1,ARMCX4,DNAH9,EBI3,EGR3,ELAVL2,FCGRT,CHL1,GCNT2,CSDC2,STON1,RNFT2,SCIN,L1CAM,STMN1,LYPLAL1,RTL5,ALDH1L2,NKX2-2,NRGN,NALCN,TMEM206,DGLUCY,ELMOD1,NTNG1,ZNF365,TTBK2,NECAB1,MTCL1,SEMA4A,SATB2,ARHGEF12,TIAM1,AGMO,FSTL5,EML6,PLPPR5" Coexpression M7873 Genes down-regulated in macrophages: LYVE1+ [GeneID=10894] versus LYVE1- [GeneID=10894]. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "AP1B1,BRINP2,NIPA1,CBFA2T2,STOML1,CLTB,QKI,SULT4A1,CRMP1,HAPLN1,CRYBB1,GALNT9,DGKG,SIRPA,SPOCK3,DNAH9,EDN3,SIDT2,CACNG2,HVCN1,TMEM151A,SDCBP2,GALNT15,GRM7,RABL2A,DDX19B,LSAMP,MGAT3,MYH3,P2RY13,NCAM1,NF1,P2RX7,PCDH8,FSD1,FAM184A,UBR7,RPE65,UEVLD,SCN2B,ST6GAL1,NLGN1,SLC4A3,SIRT2,ADHFE1,SLC37A2,P2RY12,CFAP52,NAV2,FAM219B" Coexpression M8331 Genes down-regulated in BCL6 [GeneID=604] high follicular helper T cells (Tfh) versus all Tfh. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "ADD3,AMT,DGKZ,NCOA1,ATP2B1,CALM1,SPAG9,FOXN3,TPP1,IFFO1,SEC31B,RBM39,PPP6R2,SPOCK3,SGSM2,DNAJB6,SORBS3,TNK2,EIF1,SH3YL1,FCGRT,SARAF,FYB1,BRD8,KAT7,IL6ST,ITPKB,NUCB2,NUMA1,PDE4B,HERC2P3,PLCD1,POU6F1,SNRK,RFX5,RGS10,PCMTD2,RPS20,SATB1,SFPQ,SGK1,CLSTN1,FAM168A,SYNE2,MCF2L,TCF7,TRIM2,SYNE1,TPM2,PRDM2" Coexpression M4434 Genes up-regulated in comparison of naive B cells versus memory IgM B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.15E-04 1.00E+00 4.06E-03 4.03E-02 50 200 "PARG,DGKD,MARCH3,CCDC181,ATP6V0A1,BCL7A,DDR1,USP2,LARGE1,CLCN4,SLC4A8,EXOG,EDNRA,HEYL,TENM1,CORO2B,RASL10A,GABBR1,SYT17,SESN1,GPR12,KCNJ9,LMO2,MMP17,CD200,NRGN,PCDH9,PDE1B,ABCB1,RETREG1,RASGRF1,RADX,SATB1,SCN3A,HKDC1,ZHX3,CDK19,ATP11A,EXOC7,DNMBP,SZT2,TIMP4,TMOD1,CA14,SSBP2,ZBTB16,SLC30A4,PRDM10,SCG2,JPH3" Coexpression M10021 Genes up-regulated in tumor associated macrophages conditioned by: glioblastoma versus colorectal adenocarcinoma. MSigDB C7: Immunologic Signatures (v6.0) 3.17E-04 1.00E+00 4.07E-03 4.05E-02 49 195 "C3orf14,KLRC4,PCDH19,RTL9,AMPH,BSN,CALB1,STOML1,CRMP1,PITPNM3,PNPLA8,EDIL3,EGR3,EPHB1,EFS,F8,ABLIM2,SRRM4,DNER,GATM,GDF9,MSL3,GRM8,KCNJ4,ZNF667-AS1,SAMD5,MYT1,NAP1L3,NDUFA5,PRRX1,FA2H,CEP41,PTAFR,SCN7A,PPP1R9A,KANSL3,MTERF2,PALLD,ERC1,BEX1,TAC1,TMEM178B,RNF175,ZNF610,ZIC3,LYPD6,TCEAL7,PRTFDC1,CPNE4" Coexpression M8906 Genes down-regulated in CD4 [GeneID=920] T cells versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 3.17E-04 1.00E+00 4.08E-03 4.05E-02 46 180 "ACLY,GPR158,PCDH19,OSBPL1A,APLP1,TNRC6C,NCOA1,ATP6V0A1,RIPK1,KMT2C,CLTB,NCOR1,MYADM,SEC16A,CPEB2,DTNB,E2F5,SNX29,SH3GLB1,EIF1,ATP8A2,GLUL,GPD2,EML4,TPPP,IRAK3,KIT,LIG4,MITF,PLEC,CCDC112,ANKRD6,ELMO2,TTC17,KDM4B,ZCCHC24,GLT8D1,DIP2A,TACC1,IQCE,SLC44A1,VAV2,PPP1R3F,MARCH8,KAT6A,SPATA13" Coexpression M13256 Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.18E-04 1.00E+00 4.08E-03 4.05E-02 48 190 "BEND6,SRPX,CEP126,NRP2,CA12,PRC1,LRRFIP1,CLGN,CHI3L2,CLU,ZNF521,VCAN,HEPH,NR1D2,ECM2,EBF1,EGFR,PCOLCE2,ETV1,SCARA3,GALNT15,GPER1,HAS2,SCRG1,HNMT,KCNK2,KITLG,MMP16,SFR1,CLDN11,PDE1A,PDE4B,PDGFRA,GNG2,ANLN,GPSM2,PRRX1,PTN,VEPH1,RPS6KA2,WLS,TNFRSF19,FHOD3,SLC2A5,PDZRN3,PLCB1,PSD3,TGFBR3" Coexpression 16109776-TableS1 Human Leukemia_Verhaak05_568genes GeneSigDB 3.30E-04 1.00E+00 4.24E-03 4.21E-02 93 427 "TKTL1,ADCY2,APP,PROM1,WASF1,BAIAP3,THSD7A,CAST,RUNX1T1,CD86,CD38,CACNA2D2,B4GALT6,ARHGAP22,NRXN2,CLU,HOMER3,COL4A5,C2CD2,CLIP3,SNCAIP,CSF3R,VCAN,PPP1R16B,ST18,CX3CR1,TOX,SCRN1,DPYSL2,OPTN,LPAR6,EPS8,CHST15,FGF13,FGFR1,FGR,FHL1,EVL,GALC,GATM,HPGDS,GPM6B,LILRA1,GSN,SLC2A6,HNMT,IFI16,KIT,TM6SF1,MEF2C,MEIS1,MEST,MN1,CD200,MX1,NBL1,NCAM1,PALM,PDE3B,PDE4B,CYTL1,ABCB1,SERPINE2,SNX10,GPSM2,FTO,SCHIP1,PILRA,PRODH,SIDT1,PTAFR,PTX3,ROBO1,BAALC,RPS6KA2,STK32B,MEG3,SNCA,EPB41L3,AGTPBP1,DMXL2,PCDHGC5,ARHGEF12,TLR4,TMOD1,TRH,KCNE5,SSBP2,VLDLR,PRDM2,SLC38A1,ITM2C,TRIM16L" Coexpression 12610208-Figure1-2 Human Breast_Hedenfalk03_38gene_down_subsetBRCAx GeneSigDB 3.33E-04 1.00E+00 4.26E-03 4.24E-02 12 27 "ARHGEF7,SRSF11,FGFR1OP2,CASP8AP2,SYNCRIP,HPS5,AFDN,NAP1L1,TNPO2,OCIAD1,ADGRL3,EVI5" Coexpression M4196 Genes up-regulated in PC3 cells (prostate cancer) after knockdown of EZH2 [GeneID=2146] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.37E-04 1.00E+00 4.31E-03 4.28E-02 201 1037 "ASIC1,ADAR,AXIN2,ADRB2,AGT,SORCS2,MARCH4,OGT,ANK1,SEMA7A,PPFIA4,KCNAB2,APBB2,DGKD,APP,RGS20,CAPRIN2,SLC4A4,ATP2A2,BACH1,DCAF5,CFLAR,JAZF1,CA12,PTBP2,CAST,SPAG9,USP6,SCARB1,NEURL1,CDC42,CCPG1,NOG,UBE2L6,B4GALT6,SLIT2,PPT2,QKI,HOMER3,ARMC8,BAG4,ACBD5,CNRIP1,NECTIN3,CREB5,CSF1,SOCS5,KIAA0040,UBXN2A,CTH,MYADM,KIAA0513,KCTD8,PABPC5,DNAL1,CNIH3,CPEB2,RCAN1,ARRDC4,DNAJB6,FIS1,E2F6,EDN1,ANKRD46,SEMA3D,OPTN,PHF20L1,SUGP2,EIF5,APC2,RPS6KC1,EFEMP1,ST3GAL6,FGF1,BAIAP2,POLK,CAP2,ANKFY1,SLC37A3,CGREF1,FYB1,CAB39,NEK6,ERAP1,DNER,GCNT2,GHR,MAP7D2,FERMT2,GPER1,GPR37,GRB10,LINC00839,IL1RAPL1,ADAMTS6,ZHX1,FRMD5,BACH2,IFI16,RBPJ,IL6R,IL6ST,DIPK1A,JAK2,KCNB1,KLC1,KPNA5,LAMP2,LMO2,NCOA7,LSS,SMAD1,GPR155,MAP2,AQP11,MATN2,MATN3,SHC3,MEIS2,MEST,KITLG,POC1B,MSI1,MSRA,MT1M,MX1,MXI1,NCF2,NPTX1,OXTR,PFKFB2,PFKFB4,SERPINE2,SERPINI1,XRN1,SCHIP1,PPP3CC,VSTM2L,PRKAB2,PKIA,SAMD9,WBP1L,PXK,ZSCAN32,PTX3,TMEM145,TTC13,QDPR,C1orf54,SUSD4,RBBP6,REV3L,RGS4,SLC25A36,ZFHX4,ROBO1,AP1AR,SCP2,MRAS,SGK1,FAM102A,SLC1A3,CCDC88A,SHANK2,SLC22A4,TMCC1,TNIK,KDM3A,KDM4C,KIF1B,TAB2,COLGALT2,ZNF302,THSD1,NXT2,RGL1,NECAB1,SLC37A2,KLHL4,TCF4,TCF7,WASHC4,SYNE1,TK2,LRRC8A,TP53BP2,TPM1,RGMB,TUBB2A,HIRA,PITPNB,PORCN,XRCC4,FMN2,SYNC,PPP1R3F,ITM2C,FBXO36,NLRP3,FRMD6,NETO2" Coexpression M6708 Genes down-regulated in endothelial cells: untreated versus exposed to E. burgdoferi. MSigDB C7: Immunologic Signatures (v6.0) 3.39E-04 1.00E+00 4.33E-03 4.30E-02 39 146 "CLK4,SORCS1,HFM1,RGS9,HIP1R,METTL6,CABP1,ZC3H11A,NR1D2,DMTF1,NRG3,GNG4,GPER1,SHISA6,HSP90AA1,PLD5,KLRC2,MYO6,NACA,NNAT,OMG,PRTG,PFKP,NLE1,ING3,VSTM2L,PSD,SCN3A,SCN4B,TRA2B,ITSN1,SLC2A5,ACSBG1,TPD52L2,UBC,DNAJC12,SF1,WNK1,FZD3" Coexpression M2226 Genes up-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.40E-04 1.00E+00 4.34E-03 4.31E-02 107 504 "NDRG2,RNF157,OSBPL1A,ALCAM,ANK3,MYH7B,PPFIA1,EPB41L5,MIER1,SEMA4G,ASPH,NRP2,C5,CCNT1,REPS2,CDH2,CLCN3,CLU,TMEM59L,ABCG2,HECTD1,MAGED1,C2CD2,SV2B,EXOG,DMPK,DUSP9,DNM1L,ABCC9,EDNRB,KMT5B,ING4,PAN3,MRVI1,ABCA8,SH3YL1,ACSL4,DLC1,FECH,GTF2IRD2,CAP2,FOXO3,FLT1,ARFGAP2,OGA,MTHFD2,GHR,FERMT2,GRB10,GUCY1A1,AGFG1,C2orf72,IGFBP1,IGSF1,ITIH2,KIF2A,MBNL1,MSR1,NAP1L1,PBX1,OLA1,SEMA5B,PMP22,MAGEL2,SEPT4,DRAM2,MASP1,VPS13C,SLC22A23,PTPRB,PTPRD,NWD1,MEG3,SEMA6D,SLC30A10,ITSN1,WDR37,SLC6A8,YPEL4,TMEM132D,CPEB4,SNCA,CLASP2,MESP1,ST5,APOM,NSFL1C,ABCC8,DDHD2,WWC1,PUM2,FRYL,TF,TGFBR3,SLC44A1,TMEM9,TRIO,TUBB1,AMOT,NSD2,PORCN,FTSJ1,ZFAND5,EMSY,CIAPIN1,MRPL47,SNX14" Coexpression M2491 List of genomically imprinted genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.44E-04 1.00E+00 4.39E-03 4.36E-02 21 63 "APOC2,SFMBT2,SGCE,CD81,DRD1,GATM,GNAS,GRB10,HTR2A,SCIN,MEST,NNAT,CNTN3,MAGEL2,RASGRF1,MEG3,PPP1R9A,SNRPN,PEG10,UBE3A,MKRN3" Coexpression M244 Genes down-regulated in brain relapse of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.44E-04 1.00E+00 4.39E-03 4.36E-02 26 85 "KIAA1324,ALCAM,CA12,CLGN,CLCN3,COL4A5,SLC4A8,GREB1,ERBB4,EVL,TOX3,IL6ST,MAPT,SIDT1,QDPR,RET,STK32B,CXXC4,MAPKBP1,KDM4B,ASTN2,PSD3,CHST8,DNAJC12,NPDC1,DNALI1" Coexpression M1917 Genes up-regulated in neural stem cells (NSC) at both 36 h and 60 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.48E-04 1.00E+00 4.43E-03 4.40E-02 31 108 "SORCS2,APBA2,IGDCC4,KIF1A,CRLF1,DNAJB5,CSF1,SIRPA,FBXO25,FCGRT,OLFM1,SORBS1,GSN,GSTM5,KCNC1,VWA5A,NNAT,PDE2A,TMEM38A,PLCD1,SLC22A23,GDPD2,PTPRE,PYGM,RALGDS,S100B,DGLUCY,EFHD1,ZMAT3,NACC2,RPRM" Coexpression M2367 "Genes down-regulated in HEK-293 cells (fibroblast) upon knockdown of CTBP1 but not of SATB1 [GeneID=1487, 6304] by RNAi." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.49E-04 1.00E+00 4.43E-03 4.40E-02 96 444 "ARID1A,NME5,SPOP,OGT,TMEFF1,PDE8B,ATP1B3,BID,NRXN3,MYL6B,NGEF,ABCG2,RCHY1,HAPLN1,RNF14,CLIP3,DOCK4,TCAF1,SNPH,PABPC5,FBXL5,SNAP91,DNAH9,DYRK1A,DCTN4,GPHN,ADGRV1,TESK2,PPP1R1B,ZCCHC17,FYN,SDCBP2,DKK3,GABRA2,HBS1L,TMEM8B,MTHFD2,GHR,NUDT21,ATE1,GRM2,TMEM25,DDX19B,KLF12,HSF2,ZNF678,KCNK1,STMN1,LMO1,MARK3,MDM4,MMP17,SESN3,BLOC1S2,MT3,CNTN3,PCDH8,PDE1A,ENPP2,PIK3CD,PLEC,PRRX1,PPP3CA,VSTM2L,MARCH1,SLC25A36,TMLHE,RYR1,RMI1,ATXN1,ATXN7,SUPT20H,ST8SIA1,DZIP1,WDR37,SEPHS1,SLIT1,INTS9,DOP1A,SOX2,SP4,MIR100HG,DIP2A,TAC3,AKNA,ARHGEF12,GPR161,TRH,TMEFF2,KLC2,PCDH20,NDRG4,CIAPIN1,PARP11,IFT88,AP3B2" Coexpression 16715129-SuppTable5 Human HeadandNeck_Jarvinen06_223genes GeneSigDB 3.51E-04 1.00E+00 4.46E-03 4.43E-02 52 211 "PKP4,ASPH,ALDH7A1,SEC11C,C1QC,CFL2,SRSF11,CNN3,CRY2,SLC32A1,OSBPL3,RASSF2,DDX46,ABI1,FEM1B,KLHL5,ETV1,SEC24B,BAIAP2,UBE2E3,SGIP1,ATP2C1,STAU2,SESN1,GK,GRB10,GRM3,VSIG4,TLX1,AGFG1,HTR2A,KPNA5,NEK1,NTRK3,OMG,PDE4B,PDE4D,SERPINE2,SMOX,PXK,PTPRD,LRRTM4,HSPA4L,SCG5,SLC12A2,SNCA,ZNF415,ZHX3,TAF9,TSN,PRTFDC1,FIP1L1" Coexpression M7007 Genes down-regulated in hematopoietic stem cells versus megakaryo-erythrocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 3.58E-04 1.00E+00 4.54E-03 4.51E-02 43 166 "ACTN1,ADCY6,USP28,SFMBT2,ATM,SCAPER,FOXK1,CNN3,SLC25A27,LRIG1,HDAC4,PLEKHO1,CHST15,RAPGEF6,GART,SESN1,TDRKH,RAPGEF4,BACH2,IL6ST,SESN3,TMIE,PTK2,EML5,CEP97,ARID4A,RGS10,WLS,AP1AR,SELL,MAGI3,ST6GAL1,ST8SIA1,DZIP1,SCMH1,TET1,MYCBP2,CEP68,TGFBR3,SSBP2,TTC3,TOM1L2,KLHDC1" Coexpression M7263 Genes down-regulated in thymus perimedullary cortical region versus the whole cortex. MSigDB C7: Immunologic Signatures (v6.0) 3.60E-04 1.00E+00 4.55E-03 4.52E-02 49 196 "ASIC2,FAM135A,SEMA7A,LGR5,CADPS,CHRD,ASTN1,B3GALT2,PROM1,SPAG9,LARGE1,ZFYVE9,NRXN2,CRYM,ST18,ZFYVE16,KIAA0087,AK5,TOM1,FOLR2,ATP2C1,DCLK2,GRIK1,KCNN2,DDR2,OPHN1,PDE1C,PMP2,PPM1B,PCDHB17P,RAB5B,SH3TC2,RFX4,SELL,SLC6A7,SLC8A2,SCMH1,SNCB,DOP1A,IDI2-AS1,DDN,SAMSN1,SZT2,PCDHA3,VAV2,WIPF1,CLDND1,MKRN3,ZNF225" Coexpression M12824 Cluster 4 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.60E-04 1.00E+00 4.55E-03 4.52E-02 49 196 "ADGRF5,CDC42BPA,AQP4,ARRB1,ST3GAL5,CFAP410,SLC16A4,QKI,CLOCK,ARHGEF10,RIMS3,SCRN1,SGSM2,FAM13A,AASS,EN2,EPB41L1,ERBB2,EFEMP1,DLC1,ATP8A1,GLS,NR3C1,IL6R,ITPKA,NINJ2,PPP3CC,GON4L,FAM184A,RPS6KA2,ATXN2,ATXN7,SMARCD3,LIMCH1,SPTB,LMO3,TROVE2,CAMTA2,ATP11A,TRIM2,SYNE1,TNS2,AHCYL2,ICAM5,DAAM2,ZBTB16,ZFAND5,WNK1,NAV2" Coexpression 18757322-TableS1 Human Breast_Creighton08_2154genes GeneSigDB 3.68E-04 1.00E+00 4.65E-03 4.61E-02 320 1739 "RALGAPA1,SERPINA3,ACLY,RBM10,ACTN1,ADD3,AP1B1,MTUS1,OSBPL1A,NME5,KIAA1324,AK2,BEGAIN,ANK3,PKP4,APAF1,APBB2,APLP1,API5,PPFIA3,CDC14B,CASK,ARNTL,ASCL1,ASPH,ZBTB10,ALDH7A1,N4BP2L1,BCL2L2,BCS1L,CFLAR,BMP7,FUBP1,RAB29,CA4,CA8,CAMK2B,CAMK2G,CAST,CARS,NFS1,PRC1,CBS,SCARB1,SYNGR3,ENTPD6,ARHGEF2,REPS2,CDC25B,ARHGAP33,LARGE1,TBRG4,CLGN,ADGRG1,RCBTB2,FOXN3,CNOT8,LHX2,CLCN3,CLU,TPP1,CLTB,QKI,NIPBL,HOMER3,IQCK,LETMD1,COL9A3,SLC4A7,LRIG1,FEZ1,FAM169A,DZIP3,GREB1,CTNND1,DOCK4,ARHGAP32,TCAF1,KIAA0513,TBC1D5,KIAA0586,IP6K1,DBI,GIT2,DBN1,ARMCX2,PLEKHM1,B3GAT3,MFAP3L,RHOBTB1,SACS,KBTBD11,DMD,DNM1,DSCAM,DTNA,ABCC5,RASGRP1,FRY,SIDT2,OPTN,EGR3,RASA4,EIF5,ING4,PCOLCE2,EML1,EIF1,ERBB4,RRAGB,GMPR2,ARMCX1,SH3YL1,TUBA1B,TUBB3,TUBB4A,EFEMP1,ATP8A1,CHST15,FDFT1,SEC24B,KIAA1109,OLFM1,FGF13,TMEM164,FHL1,IP6K2,FOXM1,FOXO3,NOP56,NBEA,SMC2,TPK1,PNMA2,MPP6,OGA,FYN,STAG2,GALC,ATP8A2,INPP5K,GART,BRD8,TCERG1,DBF4,GLS,TOX3,GLUL,RAB40B,PSRC1,GOLGB1,ADGRA3,STON1,GPER1,GPR37,TUBA1C,RAPGEF4,GRB10,DIDO1,NR3C1,GUCY1B1,MUM1,ACOT7,GABARAPL2,HMGCL,HMGCR,HNMT,IDH3A,IGSF1,IL6ST,JAK1,KCNMA1,KCNN2,KLC1,L1CAM,LMO2,ARHGAP12,MAPT,MAT2A,MATN2,MEIS1,MIA2,MID1,MXI1,NAP1L1,NELL2,NME4,NPR2,NRGN,NUMA1,PAH,PBX1,PCDH8,PFKFB3,PFKP,PIK3R1,SNX10,RETREG1,GPSM2,NLE1,PLCL1,PMP22,RETREG2,PPP2R5C,PPP5C,PKIA,PRKAR1B,MAPK9,GRAMD1C,DIRAS2,NDUFS7,SIDT1,DEF8,PTCH1,ELOVL2,SPDL1,PTPN13,PTPRE,PEX2,NKAIN1,TTC13,ACSS3,SUSD4,ARID4A,BSDC1,MORC4,RFX5,MRPS18A,SEC61A2,NUDT11,DCUN1D2,EXD2,CARF,PCMTD2,NEK11,MAP6D1,RTN1,RXRA,SARS,PPM1E,FERMT1,SHMT2,R3HDM2,ABLIM3,SLC1A2,SMTN,SLC6A8,SHANK2,KBTBD4,SLC15A2,EFHD1,ATF7IP,SLIT1,CXXC4,SMARCE1,RCOR3,LMBRD1,PALLD,PDZRN3,SOX3,TNIK,SPATA7,KDM3A,CLUAP1,GLT8D1,IQSEC2,CDK19,RAP1GAP2,SPART,PBLD,ZNF302,CEP68,KANK1,KLHL7,JMJD6,ARHGEF9,DNAJC9,TACC1,TCEA1,KIAA0930,TRIM2,RPGRIP1L,PSD3,PCDHAC2,PUM2,SIK3,SIRT1,TMEM121,AKTIP,CBX5,HEY2,TMPO,BEX4,TNNT1,TPM1,PDSS1,RUNDC3B,TRPC1,TUBB2A,SGK3,CADM1,UBE2H,VLDLR,TBC1D15,WIPF1,KLC2,ZNF32,ZNF74,LRP8,RNF103,TUBA1A,CIAPIN1,NAV2,PCBP4,PLSCR4,MARCH8,UBE3B,ACTR3B,FXR1,NETO2" Coexpression M4991 'PAX-FKHR signature': genes up-regulated by PAX3- or PAX7-FOXO1 [GeneID=5081;5077;2308] fusion in primary alveolar rhabdomyosarcoma(ARMS) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.68E-04 1.00E+00 4.65E-03 4.61E-02 20 59 "ABAT,ALK,ANK2,TMEFF1,ARRB1,MARCH3,JAKMIP2,RASL10A,GPM6B,INPP1,KCNN3,VWA5A,MN1,MYCN,NELL1,NRCAM,MORC4,MEG3,SGK1,TCF7L2" Coexpression 18689800-TableS5 Human EmbryonicStemCell_Thomas08_839genes GeneSigDB 3.73E-04 1.00E+00 4.70E-03 4.67E-02 157 786 "ARID1A,ADORA2A,AP2A2,OGT,PHF12,APBA2,APBB1,APBB2,APC,APLP1,APP,CASK,ZBTB10,NCOA1,ATM,BMP7,FUBP1,JAZF1,BTRC,CAMK2D,CCNH,CDC25B,CDC42,MAP4K4,MAGED1,TBPL1,CREM,RBM39,RNF14,NCOR1,NCOR2,CSNK1E,HDAC9,MAML1,MYEF2,ARNT2,MED12,NR1D2,DMTF1,ATN1,DNAJB6,E2F5,EEF1D,EIF4G2,ERBB2,ERCC2,ETV1,ZNF589,FGFR1,FOXM1,STAMBP,TRIM16,CAMKK2,ATP2C1,KHDRBS3,STAG2,DKK3,ZMYND11,ZNF274,NEK6,BRD8,TCERG1,RNPS1,GLI2,CBX1,ATF7,GRB10,RAPGEF1,ZNF496,SOX21,HMGB1,IL6ST,ITGAV,SMAD1,MBD1,MDM4,MEIS2,AFF1,MXI1,MYCN,MYO6,NAP1L1,NCAM1,NFE2L2,NFYA,PAX6,PBX1,PDPK1,POLR2F,PPP2R5C,PPP3CA,PPP5C,PKN2,MAPK3,MAPK7,MAPK8,PTK2,RBBP8,RGS12,RXRA,SAFB,SALL1,SATB1,HES6,SFPQ,SH3BP2,ITSN1,EPN2,SIRT2,ATF7IP,EPC1,SMARCA4,SMARCC2,SMARCD3,SMARCE1,SOX2,SOX10,SOX11,SP2,MYCBP2,PEG10,ZNF423,TROVE2,ERBIN,SUPT5H,TAF9,TBL1X,TCEA1,TCF4,SIN3B,TCF7,TCF7L2,TCF12,NSD1,CRTC1,SIRT1,TGFBR3,TIAM1,CBX5,TMPO,PARD3,TP53BP1,TP53BP2,ZNF384,TSC2,HIRA,UBTF,WIPF1,SF1,ZBTB14,ZNF24,SPHK2,POLR3H,PRDM2,NELFE,FZD3,JMJD1C" Coexpression M15456 Genes whose promoters were bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and which were up-regulated in comparison of tumor vs normal prostate tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.80E-04 1.00E+00 4.79E-03 4.76E-02 13 31 "CBFA2T2,SEPT7,ARHGAP33,CCDC151,PICK1,PDE4DIP,POM121,L1CAM,MSRA,PDGFRA,GDPD2,PTHLH,MEG3" Coexpression M2256 "Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.81E-04 1.00E+00 4.80E-03 4.77E-02 55 227 "ACTN1,OSBPL1A,SRPX,SEMA7A,SMIM29,CA12,CAMK2D,CHN1,SLC4A7,FAM171B,MICAL2,VCAN,TCAF1,AK5,TSPAN5,EGFR,LRRC17,SPEG,F3,FAM198B,DNER,GRIA1,NR3C1,MFSD2A,HAS2,DIPK1A,STXBP5,MAP2,MATN2,MEIS2,CCDC80,PDE1C,ENPP2,PCDH18,PRRX1,PKIA,SLC22A23,PEX2,PID1,BAALC,RPS6KA2,TNFRSF19,SCG5,ZNF365,SLC1A3,SLC8A1,PDZRN3,TNIK,DOK5,INKA2,EHBP1,DMXL2,RGMB,PLPP4,SYNC" Coexpression M19766 Genes silenced by DNA methylation in bladder cancer cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.90E-04 1.00E+00 4.90E-03 4.86E-02 19 55 "SLC4A4,PROM1,LRIG1,VCAN,CX3CR1,USH1C,ETV1,FCGRT,GATM,GUCY1A1,SCRG1,IGF1,LAMA2,LMO2,MITF,PTX3,ZCCHC24,COBL,TGFBR3" Coexpression M5504 Genes down-regulated in comparison of macrophages versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.08E-04 1.00E+00 5.11E-03 5.08E-02 49 197 "SRPX,ATM,PTBP2,CD38,CDH10,NDST3,STOML1,SH2B1,SEC24C,OSBPL3,DCAF8,DBT,YAF2,ELAVL3,TNK2,FYN,SRCAP,BRD8,CROCCP2,NR3C1,BTN2A1,HSF2,HSPA1L,IFI16,KCNK1,KCNN3,LSAMP,MAN2A2,MYO9A,SNTG1,PDE4B,PTPRN,TUG1,YY1AP1,ZNF365,MYH15,KIF21B,MAPK8IP3,CEP68,DDHD2,SYNE1,TGFBR3,TLL2,AMACR,ZBTB14,ZNF184,MVB12B,FXR1,LAS1L" Coexpression M2155 Genes up-regulated during pubertal mammary gland development between week 6 and 7. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.08E-04 1.00E+00 5.11E-03 5.08E-02 49 197 "ACLY,TAOK1,OGT,PI16,GPAM,ATP1A3,ATP6V0A1,CA8,ARHGEF2,FADS2,QKI,CP,DAPK1,IP6K1,SIRPA,ZEB2,DNM2,PDCD6IP,EIF4G1,EPB41L2,PTK2B,ATP8A1,SYNCRIP,SORBS1,BRD8,GNAS,GPD1,GRB10,IL6R,IL6ST,KCNB1,KCNK3,MEF2C,NFIX,PIK3R1,FTO,PRRX1,PRKACB,MAPK8,TUG1,RAB5B,SLC2A5,SMARCA4,TBL1X,TCF7,TNS1,NR2C2,UBTF,WNK1" Coexpression M2715 Genes down-regulated in MEF cells (embryonic fibroblasts) with knockout of SNF5 [Gene ID=6598] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.08E-04 1.00E+00 5.11E-03 5.08E-02 42 162 "SERPINA3,C1QTNF1,ANK3,CACNB4,CDH10,CNTN1,CP,CRMP1,CTH,CD99L2,EFNA3,PCOLCE2,RCAN2,RABEPK,SPEG,MRVI1,EFEMP1,FGF13,FOXG1,PDLIM5,NSG1,GABRB1,ATP8A2,ITGA7,MYH3,OLR1,PRKAR1B,SYTL2,PTPRZ1,RFX3,KIRREL1,RPS6KA2,SLC1A6,TET1,SNCA,BEX1,TRO,UCHL1,CELF4,SLC30A4,STMN4,KCNAB1" Coexpression M15047 The 'NPM1 signature 3': genes down-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.08E-04 1.00E+00 5.11E-03 5.08E-02 42 162 "ACLY,ADAR,LTBP4,DGKD,DDO,AQP4,CAPN3,RUNX1T1,WHRN,ABCG1,CS,SIPA1L1,PPP1R16B,SCRN1,EEF1D,LPAR6,PLEKHO1,FGFR1,FHL1,CAMKK2,TPPP3,GAD1,GPM6B,RNFT2,GUCY1B1,CD200,NBL1,PDE2A,PDE4B,PDE4D,RETREG1,POU6F1,PSMA6,SNRK,RYR1,FHOD3,EMC1,SPTAN1,TCF7,ZNF384,KCNE5,LAMP5" Coexpression 14583454-Table4 Human Brain_Godard03_36genes GeneSigDB 4.10E-04 1.00E+00 5.13E-03 5.09E-02 14 35 "ADCYAP1R1,ADD3,CHI3L2,CSF1R,FEZ1,DAPK1,GABBR1,ITGA7,KCNN3,MMP16,NCAM1,NTRK2,PLXNB1,TNR" Coexpression M379 Genes down-regulated in dendritic cells: wildtype versus NFKB2 [GeneID=4791]. MSigDB C7: Immunologic Signatures (v6.0) 4.11E-04 1.00E+00 5.14E-03 5.10E-02 43 167 "AS3MT,ADD3,PHYHD1,CDC14B,ARHGAP5,ATP2B1,GPR146,LRRFIP1,SLC25A27,IPCEF1,RIPOR2,ELMO1,COPS7A,MTX3,PHF20L1,RASGRP2,RCSD1,FGF13,IQGAP2,ADAMTS6,BACH2,ACOT7,KLRC2,MDM4,SLC11A2,PDE2A,PLCB2,PPP2R5C,SIDT1,TTC13,RFX3,ATP8B4,SELL,RASA3,WDR37,USP33,ARHGAP26,RAP1GAP2,TCF7,PIK3R5,PDSS1,CLDND1,CAB39L" Coexpression M6809 Genes up-regulated in B lymphocytes: expressing IgM BCR [GeneID=613] fusion and untreated versus expressing IgMG BCR [GeneID=613] fusion and treated by anti-HEL. MSigDB C7: Immunologic Signatures (v6.0) 4.12E-04 1.00E+00 5.14E-03 5.11E-02 47 187 "KLHL13,PLA2G6,CDC42BPA,CDC14B,ATP6V0A1,BLM,CERS5,ADGRG1,PPT2,FADS2,CNTFR,PPP6R2,C2CD2L,MRPL37,AMZ2,FECH,PRKAG2,SGIP1,NBEA,POMT1,DBF4,GRIA4,CIT,FRMD3,SLC6A17,MAN2A2,MBP,LDLRAD3,POC1B,ING3,MAPK3,EPDR1,PRODH,ZDHHC4,KIRREL1,PREX2,PEG10,WWC1,TCF7,CBX5,SLC35A4,TOM1L2,MICAL1,SLC38A1,PCBP4,MVB12B,RNF170" Coexpression 18691415-Table5e Human Colon_Solmi08_204genes GeneSigDB 4.13E-04 1.00E+00 5.15E-03 5.11E-02 46 182 "CDC7,OSBPL1A,MAP4K3,NUMB,ATP6V1G2,SPAG9,INA,LRRFIP1,SLC22A6,ARHGEF6,CDC42BPB,RGS6,KIF26A,MATR3,DCC,DNAH9,DYRK1A,FGFR3,HPCAL4,SGIP1,GALR1,ZNF638,OS9,GNAS,GRIN1,HAS2,LIFR,MSR1,MYO5A,NACA,NEK1,PAH,PCDHGC3,PDE4B,PDPK1,ANLN,PPP2R2B,ARMC5,SLC15A2,TCEA1,ITGB3BP,ZMAT3,TP53BP2,ETNPPL,SCG2,ACTR3B" Coexpression M5664 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute infection: S. aureus versus S. pneumoniae. MSigDB C7: Immunologic Signatures (v6.0) 4.13E-04 1.00E+00 5.15E-03 5.11E-02 46 182 "ADD3,AK2,MRTFA,APC,SYNJ2,WASF1,CAPN3,CHRNA4,CLCN4,FAM189A2,COL9A3,PREPL,CSF1,TM9SF4,DBT,DCC,DLG3,HIPK3,PCOLCE2,EPB41,KIAA1109,FGF1,FHL1,STAU2,ZMYND11,ARFIP1,GLS,GPM6A,GSN,AGFG1,INPP5B,KCNQ2,KIF2A,MSR1,NUMA1,STRN3,LRP12,POU3F4,CARF,PPP1R9A,SLC2A5,SLC15A2,ZEB1,TRIO,RUSC1,MFF" Coexpression M4263 Genes up-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.21E-04 1.00E+00 5.23E-03 5.20E-02 24 77 "NDRG2,ADD3,SEMA6A,LCORL,ATP1A1,ABCG2,SPOCK2,OLIG1,EDNRA,EDNRB,SLC43A2,C2orf88,GALNT15,IQGAP2,NR3C1,SCRG1,NTRK2,PDGFRA,TTLL7,IL17RB,CPEB3,ST6GAL1,SULF2,ZBTB16" Coexpression 16849537-SuppTable4 Human StemCell_Davicioni06_106genes GeneSigDB 4.21E-04 1.00E+00 5.23E-03 5.20E-02 24 77 "ABAT,ALK,ANK1,ANK2,TMEFF1,ARRB1,JAKMIP2,EYA1,GATM,MSTN,GPM6B,DIPK1A,ITPKB,VWA5A,MN1,MYCN,NELL1,NRCAM,EPB41L4B,MORC4,MEG3,SOX11,TCF4,TCF7L2" Coexpression 19377508-SuppTable3 Human Lymphoma_Chin09_65genes GeneSigDB 4.21E-04 1.00E+00 5.23E-03 5.20E-02 17 47 "ABR,MAP4K3,BMP7,CCNH,CD86,CD38,NEK6,BACH2,ITPKB,KCNN3,LMO2,OGG1,PCDHGC3,RASGEF1B,PRKACB,PTK2,WIPF1" Coexpression 16319131-table1 Human StemCell_Sun06_32genes GeneSigDB 4.26E-04 1.00E+00 5.27E-03 5.24E-02 11 24 "SGCE,CD81,GABRB3,GNAS,GRB10,HTR2A,NNAT,MAGEL2,MEG3,SNRPN,UBE3A" Coexpression 17711579-Table2a Human Testicular_Duale07_24genes GeneSigDB 4.26E-04 1.00E+00 5.27E-03 5.24E-02 11 24 "MTMR3,TAOK2,PLEKHM1,MBNL2,KLF12,MIER3,MYCN,ATXN1,RGL1,LEFTY2,MARCH8" Coexpression M16867 The 'MLL signature 2': genes down-regulated in pediatric AML (acute myeloid leukemia) with rearranged MLL [GeneID=4297] compared to the AML cases with intact MLL and NPM1 [GeneID=4869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.28E-04 1.00E+00 5.30E-03 5.26E-02 65 280 "AP1B1,APP,LGR5,ATP2A2,WASF1,MYRF,BAIAP3,HIP1R,RUNX1T1,B4GALT6,CHD1L,SIPA1L1,PPP1R16B,ST18,MATR3,DAPK1,DBN1,ELMO1,CEP170,EEF1D,EGR3,FDFT1,FGFR1,SYNCRIP,TRIM16,RASL10A,ATP2C1,SEPT9,SESN1,GGT5,BRD8,HPGDS,GLS,IFI16,ITGAV,JAK1,KTN1,MN1,CD200,NBL1,NME4,NTRK2,CYTL1,OLA1,ABCB1,SERPINE2,TNPO2,PTHLH,RIPOR1,RALGDS,NUDT11,BAALC,RPS6KA2,STK32B,SCN2A,SLC12A4,MCF2L,TIE1,TPD52,TRH,TTC3,DNAJC12,PITPNB,NAV3,SMIM8" Coexpression M12362 Genes up-regulated in RMS cells (rhabdomyosarcoma) expressing PAX3 or PAX7 fusions with FOXO1 [GeneID=5077;5081;2308] compared to the fusion negative cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.38E-04 1.00E+00 5.42E-03 5.38E-02 21 64 "ABAT,ALK,ANK1,ANK2,TMEFF1,ARRB1,JAKMIP2,EYA1,GATM,GPM6B,DIPK1A,ITPKB,VWA5A,MN1,MYCN,NELL1,NRCAM,EPB41L4B,MORC4,MEG3,TCF7L2" Coexpression M2538 Genes indentified by RNAi screen as regulating infection of THP-1 cells (macrophage) with Mycobacterium tuberculosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.39E-04 1.00E+00 5.42E-03 5.39E-02 64 275 "AP1B1,GPR158,LTBP4,KIF6,C6orf89,BBS2,ZNF599,DIRAS1,HIP1R,SLC24A2,COL11A2,CPS1,PLXNA4,RIMS2,DCAF4,ECE2,SCRN1,AK5,DMPK,GOLT1B,FCGR1B,ACTL6B,SLC37A3,KIAA1841,PCDH17,KIAA1958,MUM1,FRMD5,HPCA,CLVS2,IL17D,MN1,MSRA,P2RY13,NELL2,ODF2,ZNF827,PFKFB4,PIK3R1,IRX1,MAPK10,SLC26A11,PXK,RAB3IL1,RALGDS,REV3L,KLHL11,TMEM206,STX1B,TNFRSF19,SYT1,ASTN2,TAC3,ANO4,NAT16,AKTIP,FBXL16,ARL10,ZNF384,ZXDA,CIAPIN1,GAL3ST3,AMN1,HNRNPA3" Coexpression M8147 Genes up-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "NME5,APOC1,RASL11B,ATP2A2,ADGRB2,THSD7A,KRIT1,INA,CDH2,DCLK1,LARGE1,FHL5,COX4I1,FEZ1,SIPA1L1,ZNF337,YTHDC1,DNAJC6,VPS13B,PTK2B,ARFIP1,GFAP,STMN2,SLC2A6,MAN1B1,KLRC3,LSS,MKLN1,MOG,NCAM2,OPA1,SEPT4,PTPRD,RGS12,SCNN1D,INAVA,SOX11,STX1A,TAF9,WWC1,FBXW11,TGFBR3,TPM3,CHST5,ZNF154,PRDM10,UBE3B,PHTF2,JPH3" Coexpression M7681 Genes down-regulated in ankle joints from SPHK1 [GeneID=8877] knockout: TNF [GeneID=7124] over-expression versus control. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "GRAMD1B,ADRA1B,SRPX,ASPA,CBLN1,CDH8,DLGAP2,SH2B1,CX3CR1,DGKG,LYPD1,NR1D2,F5,DLC1,ATP5PD,USP21,MYOZ2,GLRB,STMN2,GRIN1,SOX21,HMGCL,HTR2A,IDH3A,KIT,KLRC3,MEIS2,MYBPC1,SERPINI1,CAMKV,BCAS3,PID1,RGR,YY1AP1,PCMTD2,SAFB,ASRGL1,BCAN,BTBD7,DOP1A,GLT8D1,TCF4,CBX5,TLR4,TSN,VIPR2,MFF,EPM2A,RNF146" Coexpression M5495 Genes down-regulated in comparison of macrophages versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "MARCH3,CARS,SYNGR3,LOC730101,NDST3,STOML1,OSBPL3,KIAA0040,TBC1D5,MAML1,GIT2,DYRK1A,E2F5,EEF1D,EGR3,TNK2,EXTL1,PTK2B,TESK2,RNPS1,GLDC,RNFT2,MUM1,HSF2,KCNH2,MAT2A,MEIS1,NASP,CNOT4,POLG,PRPSAP2,ZCWPW1,ZDHHC4,RGS7,ROBO1,SATB1,SCN3A,SMPD3,PPM1E,CDK5RAP3,ZNF667,ZC4H2,ARHGEF9,CLASP1,SYNE1,CRB1,ITM2C,MARCH8,LAS1L" Coexpression 19904269-ST1 Human Breast_Agthoven10_251genes GeneSigDB 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "CPNE2,UNC5A,KIDINS220,BCAR3,PCDH10,APC,GAS7,FUBP1,KALRN,ARHGAP33,NCOR2,ABCG1,CHD5,DBI,DNAJC6,CERCAM,RAB9B,ERBB4,APC2,RTN3,OLFM1,USP21,PNMA2,SRCAP,GNG4,MAN1B1,HSD17B1,SOWAHA,LAMP2,MEIS2,NELL2,NPTX1,KSR2,PCMT1,RTN1,ZNF365,PEG10,ZC3H13,ARHGAP26,RHBDL3,WWC1,ACSL6,RALYL,PCDHA6,EIF4ENIF1,TOM1L2,SYNC,NAV3,ACTR3B" Coexpression M5253 Genes down-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "ARHGAP5,DNAH17,NOL4,SLC16A4,PPT2,FADS2,SLC4A7,RCHY1,PREPL,GAPVD1,KIAA0753,DLG2,EFNB3,LINC00599,FCGR3A,FKTN,FGF1,ATP5PD,DOT1L,PRRC2B,GRM2,IRAK3,PADI2,KCNF1,KTN1,LMO2,MAPT,ZNF92,MYO6,HNRNPM,NAP1L3,CDK18,POU3F2,PRKACB,PRODH,PTPRN2,PYGM,RAP1GDS1,ITSN1,DOK5,PEG10,IQSEC2,CLASP1,TPM1,RUSC1,FLRT1,SLC26A10,ZNF142,ZNF177" Coexpression M3200 Genes up-regulated in comparison of naive B cell versus dark zone germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 4.62E-04 1.00E+00 5.66E-03 5.62E-02 49 198 "CLK4,NDRG3,SLC12A5,TAOK1,AMT,CDK5R1,LARGE1,CLCN4,AKAP6,ARHGEF10,PPP1R16B,CTNND1,ZEB2,FCF1,KMT5B,FHL1,FOXO3,TPK1,GPR153,CHL1,GCK,IRAK3,JAK2,KCNA2,MAN2A2,MBP,NEK1,NUMA1,CYTL1,VPS13C,ZSCAN2,MARCH1,RALGDS,BSDC1,RPS6KA2,LGR4,RXRA,SATB1,PPP1R9A,HKDC1,SLA,SCN3B,MYCBP2,MAPK8IP3,GSE1,MTCL1,PDLIM2,TRIO,SNX27" Coexpression 18927307-tableS2 Human Colon_Allen08_357genes GeneSigDB 4.62E-04 1.00E+00 5.66E-03 5.62E-02 57 239 "AGT,CDC42BPA,MAP4K3,DST,CACNA1I,KRIT1,USP6,CLGN,NCOR1,KIAA0040,CTH,TOMM20,CDON,FARSB,YAF2,PAN3,DLC1,POLK,UBE2E3,DCTN2,PDLIM5,FYB1,GART,GK,LOXL3,TPPP,FRMD5,RBPJ,HECTD2,MATN2,MBNL1,MBP,OPHN1,FTO,ING3,PPP3CA,CNNM2,SAMD9,PTK2,PTPRG,SETD5,SGK1,BTBD3,NBPF1,POGZ,DIP2A,SYT1,ANKRD28,TCF7L2,TCF12,WASHC4,ARHGEF12,DDHD1,CABIN1,PITPNB,ZBTB14,TRIM9" Coexpression M6915 Genes up-regulated in B lymphocytes: control versus anti IgM. MSigDB C7: Immunologic Signatures (v6.0) 4.66E-04 1.00E+00 5.70E-03 5.66E-02 41 158 "SEMA7A,APOC2,ARNTL,FUBP1,C1QC,CERS5,CCNT1,USP2,ENTPD6,COPB2,PLAA,CLTB,USP6NL,IRAK4,COPS4,CALCRL,USP16,TPK1,NPTN,GAA,AHCYL1,NCKAP1,GRK4,ATG4C,IL6ST,NCOA7,FTO,POLR2F,PRKAB2,PTK2,TTC13,RBBP8,MRPS18A,ACER3,PTGR2,ITSN1,ST3GAL3,NEK4,WRN,ZFAND5,ST7" Coexpression M2827 Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL21 [Gene ID=59067]. MSigDB C6: Oncogenic Signatures (v6.0) 4.68E-04 1.00E+00 5.73E-03 5.69E-02 47 188 "SPARCL1,SEMA7A,ALDH4A1,BAIAP3,USP2,ARHGAP22,AATK,ARHGAP32,DGKG,ST8SIA3,ZIC4,OLFM1,AGAP2,IQCG,DPYSL4,GABRB3,GDF9,GNAL,LILRB4,GRIA4,FAM107A,GUCY1B1,OPRL1,GPR85,FA2H,PTH1R,PTPRN,PTPRO,PTX3,PYGM,NUDT11,PAQR6,SCN8A,FUZ,SLCO1A2,MYH15,KIF21B,SPP1,SPART,SST,ELOVL4,ABCC8,PCDHA5,TF,UGT8,VSNL1,NDRG4" Coexpression 19286929-SuppTable2i Mouse Lung_Rangasamy09_248genes GeneSigDB 4.71E-04 1.00E+00 5.75E-03 5.72E-02 43 168 "LCORL,ARNTL,ATM,FUBP1,SCAPER,FOXK1,CREM,PHF14,ARNT2,NR1D2,EBF1,FEM1B,EGR3,ETV1,FOXG1,FOXF2,ATF7,NR3C1,ZBTB45,KLF12,BACH2,MEF2C,NFYA,PRRX1,ANKHD1,SATB1,HES6,BTBD7,ATF7IP,SOX2,SOX11,SIN3B,TCF12,AKNA,THRA,HEY1,HEY2,NR2C2,TRPS1,ZBTB14,ZIC1,ZIC3,PHTF2" Coexpression M1894 Genes up-regulated in dendritic cells (5 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]. MSigDB C7: Immunologic Signatures (v6.0) 4.86E-04 1.00E+00 5.93E-03 5.89E-02 35 129 "ADRA1D,SPARCL1,AMH,ADGRB3,CACNA1I,SEC24C,SV2B,TMCC2,OLIG1,EDNRB,RASA4,MTSS1L,TPPP3,MEGF10,ARPP21,PCDH17,GPR75,GPER1,GRIA4,INSM1,KCNJ10,KCNK2,SAMD5,JAKMIP3,NAP1L3,OXTR,PRIMA1,ARHGEF10L,RAVER2,SLC4A3,EFHD1,ARFGAP1,SP2,BEST1,FSTL5" Coexpression 16455954-TableS1 Human StemCell_Dekker06_600genes GeneSigDB 4.87E-04 1.00E+00 5.93E-03 5.89E-02 111 531 "ESYT2,ALCAM,ZNF687,ZFAT,ANK2,PI16,ANXA7,EPB41L5,ZFYVE28,ARRB1,ADAM15,DST,ST3GAL5,BTK,MTMR3,CALM1,CAMK2B,KYAT1,MYOM2,CDC25B,LRRFIP1,UBE2L6,CNOT8,JAM2,TPP1,ABCG2,MAP4K4,ABI3BP,SOCS5,CTNND2,KIF26A,DAPK1,PARD6A,CDON,ECM2,SIDT2,YAF2,ELN,RASL12,CD320,FGFR3,FGR,FOXM1,USP16,RASL10A,NPTN,TBR1,IQGAP2,DISC1,SEPT9,ADAM28,GHR,GPR19,FAM107A,GUCY1A1,SYNPO,HPCA,INPP1,KITLG,AFDN,MOV10,PTOV1,NASP,NINJ2,DDR2,OGDH,OPCML,TREM2,PALM,PCDHGC3,ZFYVE21,RETREG1,KCTD15,PLEC,PMP22,SDK2,POU3F4,MAPK9,PTHLH,PTPRG,PYGM,RIPOR1,TTC13,PCMTD2,SLC30A10,MRAS,SH3BP2,MAGI3,SLITRK3,LIMS2,SLC15A2,IGSF9B,LMBRD1,PALLD,GLT8D1,KDM4C,ZC3H13,KIF1B,SULF2,STXBP1,GSE1,NECAB1,TCF7L2,OBSL1,CHST8,TMOD1,NPDC1,ZNF28,WNK1,ADAMTS9,GJC2" Coexpression 18786252-TableS1 Human Breast_Liu08_1878genes GeneSigDB 4.91E-04 1.00E+00 5.98E-03 5.94E-02 214 1120 "KCNH8,ACADM,KLRC4,CDC7,ADRB2,PLA2G6,LTBP4,CDC42BPA,APAF1,APP,AQP6,PDXK,TMEFF1,PLA2G4C,DNAH17,ALDH4A1,ATM,STX16,ATP2B1,RIPK1,ADAM15,FGF17,NRP2,CFLAR,PROM1,BMP7,CDK5R1,MTMR2,CACNA1I,CDK5R2,BTRC,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAST,PRC1,CCK,CCNH,CCNT1,CD86,CD38,CDC25B,CDC42,KCNAB3,TBRG4,CRLF1,UBE2L6,SOCS6,MS4A7,B4GALT6,STOML1,ABCG2,CNTFR,MYRIP,CRY2,CSF1R,SEC24C,CSF3R,CSNK1G3,SOCS5,CYBB,DOCK4,HDAC4,DAPK3,DBN1,DCC,MYEF2,TIAM2,POM121,SACS,SRGAP3,DLG4,DMPK,DYNC1I1,DNM2,PDCD6IP,GNE,DTNA,ABCC5,USH1C,TSPAN5,EEF1D,FRY,EGFR,AASS,TENM1,ELAVL3,ELAVL4,EML1,EIF1,OLIG2,EPB41,COQ7,EPS8,ERBB2,ERCC2,EZH1,F3,F5,PTK2B,EFEMP1,RACK1,OLFM1,FGF11,FGF12,FGF13,FGF14,FGFR1,FGFR3,MAD2L2,UBE2E3,SYNCRIP,FLNC,AFF2,AKAP3,DPYSL4,IP6K3,GHR,PPARGC1A,MALT1,POLL,STON1,GPER1,NUDT21,CLASRP,FAM107A,SLC2A6,MAP4K5,HMGCR,HP,IGF1,IGFBP1,IGSF1,ITGA7,ITGAM,KCND3,KCNK1,LAMA2,MAG,MATN3,MBP,PPM1L,SESN3,MYL3,MYO5A,MYO9A,NAP1L1,NAP1L2,NAP1L3,NNAT,NME4,NOVA1,NPPA,NRDC,NRGN,OCRL,OGDH,OGG1,OPCML,OPHN1,PCDHGC3,PCSK2,PDE3B,PDE1B,PDYN,PIK3C2A,FXYD1,PLP1,PMS2,POU6F1,PPM1B,PRKACB,PKIA,PRKCG,PRKCZ,MAPK3,MAPK8,MAPK9,PROX1,RELN,PTHLH,PTK2,PTPRZ1,PTX3,QDPR,RAB3A,RAP1GAP,RNH1,SFPQ,KIF21A,SLA,CDK5RAP3,SNRPN,SSTR2,PLCB1,SYN2,TACC1,SEMA4A,TBX15,TCEA1,TEK,TK2,NR2E1,TNFRSF1B,NEIL2,RPRM,UBE2H,UCHL1,WIPF1,NELFE,ST7,SOCS4" Coexpression 17483317-TableS5 Mouse Bone_Boylan07_823genes GeneSigDB 4.97E-04 1.00E+00 6.05E-03 6.01E-02 129 632 "GRAMD1B,ALCAM,FAM135A,GAS7,APP,LGR5,SFMBT2,CASK,ASPH,ZBTB10,DDX3Y,ATP6V0A1,BACH1,BCL7A,KSR1,ST3GAL5,FUBP1,NIPA1,DIRAS1,PTBP2,SCARB1,CDH2,B4GALT6,CNN3,MAGED1,ABI3BP,IFFO1,MFSD4A,CP,AKAP12,GDA,LRIG1,OSBPL3,IPCEF1,PPP1R16B,CTH,CYBB,ARMCX2,ZEB2,GSDME,FARSB,EBF1,FAM13A,BSCL2,GPHN,STX2,EPS8,IGSF6,EZH1,CORO2B,CHST15,OLFM1,NBEA,CINP,SARAF,MPP6,FYB1,GABRA4,RAPGEF6,IQGAP2,GART,GATM,IGSF5,BRD8,RAB30,GLS,CBX1,GPM6A,LPAR4,CECR2,GSN,DDX19B,BACH2,HP,ITGAM,KIT,KLC1,LIFR,SMAD1,NAT8L,MARK3,NAP1L1,NASP,NEFH,NFIX,NFYA,SETD4,PDE2A,PDE4D,ZFYVE21,LRP12,PRKACB,GRAMD1C,DIRAS2,PRODH,PTK2,PTPRE,OXR1,KIF7,TMEM206,EMID1,ATAT1,CLIP1,ITSN1,PPM1E,CPEB3,CCDC88A,EPC1,SNAP25,KIF13A,PDZD2,SPP1,ARHGAP26,CLASP2,CEP68,STXBP1,ATP11A,SEMA4A,AGTPBP1,TRIM2,TIAM1,TMOD1,TPM3,MTCH1,ZBTB16,AMZ1,SPIRE1,MVB12B,EPM2A" Coexpression M2797 Genes down-regulated in retina cells from NRL [Gene ID=4901] knockout mice. MSigDB C6: Oncogenic Signatures (v6.0) 4.99E-04 1.00E+00 6.07E-03 6.02E-02 36 134 "ADRB2,RGS20,CCKBR,CTH,GREB1,GSDME,ABCC9,EN2,EYA1,FABP7,NSG1,MPP6,GABRA2,SALL3,CPLX2,GGT7,ATE1,HES5,KIF5C,PIK3AP1,MAP6,IL17D,PDE1C,PLEC,TNPO2,ELOVL2,PTPN13,RASGRF2,RXRG,ST3GAL3,SLC8A3,DNAJC9,WWC1,PLEKHH2,TOM1L2,HRASLS" Coexpression M12890 Genes up-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.12E-04 1.00E+00 6.22E-03 6.18E-02 62 266 "ADD3,ADORA2A,ANXA7,SHROOM2,N4BP2L1,MYRF,CA12,SLC16A4,CDC42,FOXN3,TMEM59L,IQCK,PNKD,LRIG1,FEZ1,PPP6R2,BOC,DAPK1,SIRPA,AK5,ARRDC4,ENO2,LRRC17,CEND1,EFEMP1,CHST15,MEGF10,GPR162,LOXL3,NR3C1,HAS2,ARHGAP36,SHISAL1,MYLK2,TTYH2,MATN2,MRPL42,MX1,NCAM1,NCF2,CYTL1,PIK3CD,SNX10,SMOX,CRLS1,SUSD4,RGS4,PAQR6,ST6GAL1,SNAP25,NMNAT2,KIF1B,LHPP,SULF2,HHIP,DAAM2,RBFOX2,TPM1,TPM3,NDRG4,VANGL2,FRMD6" Coexpression M5408 Genes whose expression decreases with age in normal kidney. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.19E-04 1.00E+00 6.25E-03 6.21E-02 38 144 "C3orf14,AK2,AMPD3,AMT,PPFIA1,BMP7,CACNB2,THSD7A,CTH,GPRASP1,DBT,KLHL3,AASS,GAD1,GHR,TOX3,GNAS,PCLO,FRMD3,LINC00667,MTR,NF1,PALM,PDE3B,SLC22A23,PLPPR1,SLC25A36,CPEB3,SHANK2,SP2,ZBTB43,KANK1,TPD52,FNDC5,ZNF711,WNK1,RTN4,FXR1" Coexpression M5307 Genes down-regulated in comparison of untreated memory CD4 [GeneID=920] T cells from young donors versus those from old donors. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "BBOX1,AMT,PPFIA2,ALDH4A1,ATP6V0A1,KSR1,DLGAP2,DGCR9,CPS1,ATRNL1,FAM131B,MAGI2,DRP2,MAMLD1,FAM13A,EXTL2,EYA1,NRN1,SCARA3,DLL3,MYOZ2,TUBA8,GRIK3,GUCY1A1,KCNJ10,KCNQ3,MOBP,PCBP3,GPR88,CDK14,GRAMD1C,ELOVL2,IQSEC3,ZCWPW1,SH3GL2,SORCS3,PDZD2,SSTR1,CNTN2,SATB2,PCDHA2,HIF3A,BHLHB9,TMPRSS5,DNAJC12,VIPR2,ZNF711,REEP1,FAM182B" Coexpression M9397 Genes up-regulated in Va14 invariant NKT cells: ZBTB7B [GeneID=51043] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "TKTL1,ARMC12,USP28,SFMBT2,B3GALT2,CHRNB2,ABI3BP,C2CD2L,ALKBH8,DNM2,PDCD6IP,EIF4G1,RASGRP2,RABEPK,GORAB,TACC2,ST6GALNAC3,ZMYND11,SRCAP,SESN1,PTPN5,MAP4K5,NXPH2,HSD17B1,LRRCC1,KCNA1,MPP2,MIR4697HG,NUCB2,OPRL1,PFKFB2,SERPINI1,C19orf57,ZNF493,LGR4,PDZRN3,PBLD,ACSBG1,ATP11A,CAMTA1,KIAA0930,NSD1,HEY1,TNS1,TP53BP2,NPL,PLPPR2,SNX14,NETO2" Coexpression M10030 Genes up-regulated in NK cells versus ITGAM+ [GeneID=3684] dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "FAM43B,KIAA1211,ALK,PPFIA2,CDC14B,NCAN,RIMS4,PHF19,RIMS3,SRGAP3,OLIG1,DTNB,ABCC5,ELAVL3,STX2,ZMYND15,POMT1,B3GAT1,GABRA2,GRIA1,ATOH8,TLX1,SHISAL1,SLC35G1,LRP1B,MYCN,GDAP1L1,PRKCZ,PROX1,RTN1,FUZ,EPN2,SLC6A11,SOX11,IZUMO4,FAM168A,TAC3,VWA3A,VWCE,TMEM121,HEPACAM,CLEC2L,PLEKHH2,KCNK12,TMEM163,PLSCR4,TMEM63C,DPF3,SENP7" Coexpression M6567 Genes down-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus rosiglitazone and AM580 [PubChem=77999;2126]. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "ADCY6,ADD1,PHYHD1,TMEFF1,MYOM1,CAMK2A,CLDN10,CD86,ARHGEF1,RCBTB2,SLC25A27,COL11A2,ANKRD44,GUCD1,NYAP1,SEZ6L2,RASGRP1,EPB41L1,DENND4A,MRVI1,TBC1D16,FCGRT,TACC2,ZNF274,TPPP,RFFL,GUCY1A1,ATG4C,DDX19B,SRSF12,PDE1B,PIK3R1,C19orf57,PPM1B,RIPOR1,RASGRF2,RPRD1A,CCDC82,DGLUCY,GALNT10,RASA3,NMNAT2,POGZ,STX1A,ACSBG1,CAMTA1,ARHGAP9,SMUG1,FRMD6" Coexpression M7443 Genes down-regulated in CD4 [GeneID=920] T cells treated with TGF beta: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "ALCAM,PPFIA3,ATP2B3,RNF182,CA8,LGI1,CLU,NSL1,KCTD8,AIF1L,ELN,KCNMB2,SIRPB1,FHL1,FOXM1,NEK6,LNX1,GRIK2,SCRG1,AGBL5,IRF8,USP54,IGSF1,KCNN3,INSYN2,ADAM11,SAMD5,NELL1,NRCAM,PAK3,PSAT1,MDGA2,RAB3A,C1orf54,FAT4,FIGN,PLPPR3,MEG3,DGLUCY,KIF13A,FAIM2,LHFPL4,CAMSAP2,TSN,FAM155A,SCG2,NETO2,NETO1,GAN" Coexpression M8431 Genes down-regulated in CD8 T cells: central memory versus naïve. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "DPF1,ADCY2,CADPS,DNAH17,ATP2B3,ATP6V1G2,CACNB2,CALB2,MAGI1,GPR37L1,CHM,ARHGAP22,PICK1,FAM149A,COL4A5,AATK,FAM131B,CYBB,SPOCK2,HEPH,FOLR2,GPR162,GHR,MALT1,GPR12,STMN2,GRM3,KLF12,IRF8,KCNN1,PACRG,MSR1,MYO7A,PIK3CD,PLXNB3,PPP3CA,PTCH1,PTPRN,RAB3A,DPF2,SCN2B,ZNF821,MRAS,MYH15,COLGALT2,TMEM151B,AP4E1,CDK20,TRPM2" Coexpression M8609 Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437]. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "NDRG2,ERMN,PITPNM2,APBA2,APBB1,DGKD,ATP1A1,CCNH,NOG,ZFYVE9,LETMD1,IPCEF1,GPRASP1,ARHGAP32,ZNF337,AK5,WDPCP,RASGRP2,SARAF,GGT7,ZNF638,LINC01089,BACH2,HSF2,ITPKB,KPNA5,MBNL1,BEX5,PLCL1,PTK2,ZCWPW1,GAL3ST4,RGS10,RPS20,ZNF331,CNKSR2,CCDC88A,IFT122,SNRPN,SON,ADAMTS17,SIN3B,ERCC6L2,TPM2,ZMYND8,TOM1L2,WNT7A,SF1,ZNF540" Coexpression M4596 Genes up-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "AMH,BIN1,APBA2,DGKZ,DGKD,ASPH,ATP1A2,NRP2,CFAP410,CAMK2B,CCNT1,PLEKHB1,COL11A2,DCAF4,GPRASP1,ARHGAP32,HP1BP3,AK5,KBTBD11,EGFR,RASGRP2,FCGRT,DPYSL4,GPR153,RNFT2,IL6ST,ADAM22,LYRM9,NAP1L3,NCAM1,NELL1,PDE4B,PLXNB1,PRRX1,PRPH,PTHLH,SUSD4,RPL38,ZNF331,ZFP2,SELL,RASA3,RPH3A,EFHD1,TSPYL2,KANK1,TTPA,WNT7A,LAS1L" Coexpression M6388 Genes up-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "ADCY5,PPFIA1,ATP1A2,ATP6V1G2,FMNL3,NUMBL,TMEM184B,FAM149A,SLC32A1,C1QL2,OSBPL3,SDC3,KIAA0513,DNAL1,EYA1,F3,AMZ2,HHIPL1,METTL21A,KCNN3,KIF5C,P2RY13,GPR88,RC3H2,IRX1,PTPRN2,SNX22,SCN4B,WDR47,SLN,SNRPN,LHFPL4,ERC1,DBNDD2,KIF1B,ST5,STX1A,VAMP1,TACR1,VWA3A,TNS2,CRB1,TK2,CLDND1,LGI4,AMZ1,SIGLEC10,KCNAB1,ACTR3B" Coexpression M8422 Genes down-regulated in lin- cells: TCF7 [GeneID=6932] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "ADCY2,FZD9,LTBP4,DDO,SHROOM2,PLA2G4C,DNAH17,ATP6V1G2,CAMK2G,ARHGAP22,GREB1,HDAC9,MYEF2,SNAP91,ABCC9,EML1,FCGR3A,FERMT2,GPM6B,GRM3,PTPRT,LINC00667,BRINP3,KCNMA1,LMO2,MEF2C,MOG,MYO6,NTRK3,OLR1,PC,PCSK2,CDK18,PDPK1,PFKFB2,PROX1,PYGM,RFX5,RGR,RPE,SGK1,SLC1A2,SLC1A7,SLC6A9,KANK1,SYP,SIN3B,ZNF24,KCNAB1" Coexpression M3106 Genes up-regulated in comparison of naive T cells versus central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "ASIC1,KLHL13,PITPNM2,APBA2,APBB1,LGR5,SFMBT2,TMEM263,ATM,SLC2A11,ATP6V0A1,DDR1,SCARB1,NOG,RIPOR2,SNPH,ARMCX2,AK5,SGK2,C8orf37,NBEA,NEURL4,RAPGEF6,ZNF496,LINC01550,HSF2,IL6ST,MEST,DNHD1,SLC11A2,NUCB2,OCRL,RETREG1,CDIP1,LRRN3,CEP41,DCHS2,TUG1,BEND5,GAL3ST4,SATB1,CNKSR2,SOX5,RNF175,PRRT1,TOM1L2,CIAPIN1,AMN1,CERS6" Coexpression M9929 Genes up-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h. MSigDB C7: Immunologic Signatures (v6.0) 5.22E-04 1.00E+00 6.25E-03 6.21E-02 49 199 "DPF1,ADORA2A,SLC24A4,CCDC146,FGF17,BTK,SLC25A14,CLTB,DCAF4,DAPK3,MED12,ARRDC4,SEMA3D,ELAVL3,CDHR1,CEND1,TBC1D16,MED12L,TNRC6A,GRIK2,GUCY1B1,WIF1,INSYN1,HMX1,OPALIN,ZIC5,KLHL23,MGAT3,ADAM22,NEUROD1,SKOR1,ARHGEF10L,MRPS18A,RIC8B,IL17RB,RAB3GAP1,STOX1,TTBK2,STXBP1,SYNE2,KCTD2,MEAF6,ZFP41,UPF3A,DNALI1,HRASLS,FAM13C,SLC4A10,FAM181A" Coexpression M5601 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 20 h time point that were not down-regulated at the previous time point, 18 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.28E-04 1.00E+00 6.31E-03 6.27E-02 29 101 "ADD3,ATP2B1,DST,RUNX1T1,KIAA1549L,NMT2,SIPA1L1,RHOBTB1,RABGAP1L,NR1D2,FRY,CAP2,OGA,TRAF3IP2,LILRA1,MBNL1,PDE4B,PMP22,PTPN13,REV3L,RGS4,SLC22A4,ST5,SYT11,TRIM2,SYNE1,TGFBR3,TPD52L2,TRIO" Coexpression 17533364-TableS3 Human Brain_Lastowska07_548genes GeneSigDB 5.34E-04 1.00E+00 6.38E-03 6.33E-02 74 330 "TBC1D14,CC2D2A,USP28,ARRB1,ATM,MTMR2,CACNA1D,METTL6,ZNF445,SLC4A7,MYRIP,CRMP1,HINFP,TENM4,FEZ1,ARHGAP32,TBC1D5,ALKBH8,CDON,CPEB2,PDCD6IP,SIDT2,MFSD10,ZNF589,TMEM175,MSANTD4,CHL1,CPLX1,RAB30,ADGRA3,GRIA4,TMEM25,RBPJ,NAT8L,THYN1,NCAM1,NUMA1,OGG1,CYTL1,QRICH1,PIGG,RDX,DPF2,RGS12,PBRM1,CCDC82,SETD5,ALG9,RPL15,SATB1,ATXN7,FOXRED1,ASRGL1,SH3BP2,PAAF1,DHX30,KDM4D,GLT8D1,ZNF621,CLASP2,NEK4,FAM168A,ANKRD28,TBCEL,TMEM136,TPCN2,ARHGEF12,FRYL,SIK3,MTMR14,NR2C2,CADM1,NSD2,PRDM10" Coexpression M14353 All marker genes down-regulated in the 'interferon' subclass of hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.34E-04 1.00E+00 6.38E-03 6.33E-02 18 52 "LGR5,CDC14B,FAM169A,DNM1,PHYHIPL,GRB10,HLF,NKD1,USP54,ZNF385B,CRLS1,KANSL1,TNFRSF19,SLC6A8,VWCE,AMACR,SLC13A3,ATP6V0E2" Coexpression 18024211-Webtable1 Human Breast_Bonnefoi07_202genes GeneSigDB 5.35E-04 1.00E+00 6.38E-03 6.33E-02 46 184 "ASPHD1,ACTN1,BIN1,PDXK,ARSF,ATP1A2,NRP2,SGCE,B4GALT6,TMEM184B,CNN3,AKAP12,FEZ1,ZNF337,SCRN1,ZEB2,ARNT2,KBTBD11,DLG3,RCAN1,EGFR,TUBB4A,FLT1,GABRA3,GPM6B,GRIK5,GSN,MEST,MITF,DDR2,PLP1,PMP22,SCHIP1,MINDY2,SLC25A36,SLC6A1,SLC6A8,PDZRN3,ZCCHC24,PEG10,ST5,PHLDB1,STXBP1,ANKRD28,FTSJ1,FAM13C" Coexpression M6874 Genes up-regulated during B lymphocyte differentiation: small pre-B II versus VPREB1+ [GeneID=7441] large pre-B II. MSigDB C7: Immunologic Signatures (v6.0) 5.38E-04 1.00E+00 6.40E-03 6.35E-02 42 164 "CPNE2,SNX30,OSBPL1A,ALCAM,OGT,ZBTB10,PRMT9,CACNB2,CCPG1,CHM,MAP4K4,IPCEF1,PITPNC1,CALCRL,PAN3,KATNAL1,TAOK3,POLK,INPP5K,NR3C1,PRDM5,KIT,CD200,NF1,PLCB2,SPATA6,POU3F4,PPP5C,ZIK1,FAM120C,ARID4A,DOCK10,FNDC3A,SLC12A2,TET1,CAMSAP2,TCF4,TRPS1,ZMYND8,RICTOR,MVB12B,PHTF2" Coexpression M6701 Genes down-regulated in endothelial cells: interferon alpha versus interferon beta. MSigDB C7: Immunologic Signatures (v6.0) 5.38E-04 1.00E+00 6.40E-03 6.35E-02 42 164 "ADD2,GRAMD1B,APLP1,KSR1,SYNJ2,DCLK1,PCYT1B,CX3CR1,ZEB2,SRGAP3,SEC16A,DMTF1,PTK2B,CHST15,FGR,SORBS1,FYN,GPM6B,RAPGEF1,ADAMTS6,MAP4K5,PIK3AP1,KCNK10,PDE1A,SYTL2,PTPN13,SETD5,PRR5L,SEMA6D,ITSN1,SPP1,SULF2,TACC1,FRYL,TRPC1,ZBTB38,GDPD5,ITM2C,PLSCR4,MARCH8,KAT6A,SPATA13" Coexpression 19061838-TableS3 Human Viral_Cairo08_588genes GeneSigDB 5.40E-04 1.00E+00 6.42E-03 6.38E-02 99 466 "ABAT,ACADM,ACLY,NDRG2,OSBPL1A,ALCAM,BBOX1,LGR5,PDXK,N4BP2L1,MYOM1,AZGP1,CBS,MAP4K4,FAM149A,MAGED1,CP,CREM,CRHBP,CS,SOCS5,DZIP3,CTH,GREB1,TOMM20,MFAP3L,RHOBTB1,GNE,RBM12,PLXNC1,AASS,TENM1,ETV1,RPS6KC1,ST3GAL6,FDFT1,CAP2,PDLIM5,GABBR1,SYT17,GHR,PPARGC1A,LYVE1,GLUL,CBX1,ADGRA3,GPD1,GSTT2,VSIG4,HMGCR,HP,IGF1,INPP1,KCND3,MT1M,MTR,NAP1L1,GPR88,PDCD2,SERPINE2,RETREG1,FXYD1,RC3H2,PPP1R1A,GRAMD1C,PRODH,RELN,PTH1R,ACSS3,SLC25A36,ROBO1,MEG3,SCP2,FAM102A,CPEB3,ABLIM3,SEPHS1,SMARCA4,OGDHL,RCOR3,PALLD,PEG10,BEX1,SEPT8,CEP68,TACC1,DDHD2,CAMSAP2,OBSL1,CBX5,R3HDM1,TSN,ETNPPL,ZBTB38,ZNF189,ZFAND5,MFF,MARCH8,FXR1" Coexpression 15902281-TableS1c Human Leukemia_Schoch05_530genes GeneSigDB 5.46E-04 1.00E+00 6.49E-03 6.45E-02 54 225 "N4BP2L1,ARHGEF7,CLDN10,DCLK1,RCBTB2,SLITRK5,DCT,SACS,EDNRB,FRY,MBNL2,LPAR6,USPL1,FGF14,FLT1,NBEA,UFM1,ATP8A2,WASF3,PCDH17,GPR12,SOX21,KLF12,HMGB1,HTR2A,IPO5,LIG4,SMAD9,IL17D,PCDH8,PCDH9,ENOX1,DCUN1D2,TNFRSF19,SUPT20H,RASA3,FNDC3A,DZIP1,NAXD,MYO16,MYCBP2,ZC3H13,RBM26,SPART,THSD1,ATP11A,MCF2L,DOCK9,NACC2,PCDH20,ZIC2,UPF3A,CAB39L,IFT88" Coexpression 12086872-Table11b Human Leukemia_Yeoh02_40genes_Novel GeneSigDB 5.50E-04 1.00E+00 6.52E-03 6.48E-02 13 32 "LGR5,BCL7A,CLTC,CNR1,TRAF3IP2,GLDC,AFF1,PCDH9,PDGFRA,PLTP,RXRA,EHBP1,SATB2" Coexpression 19252174-Table3 Human Leukemia_Hernandez09_66genes GeneSigDB 5.54E-04 1.00E+00 6.57E-03 6.53E-02 21 65 "USP28,GAS7,APP,CACNA1A,CACNA1D,CACNA1E,USP6,SCARB1,CDC25B,CACNA2D2,CLU,DAPK1,MAPT,PPP3CA,PPP3CC,PRKCG,PSMA6,RASGRF1,UNC5B,USP22,ZBTB16" Coexpression M18532 Genes positively correlated with amplifications of MYCN [GeneID=4613] in the SCLC (small cell lung cancer) cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.56E-04 1.00E+00 6.58E-03 6.54E-02 27 92 "DGKZ,L3MBTL4,CDR1,RAB33A,APH1A,ABCA8,LILRA1,SYNPO,SHC3,SESN3,HS6ST3,MYCN,P2RY1,PDE2A,SLC6A15,HSPA4L,ST8SIA1,SLC1A2,FAM81A,PDZRN3,NMNAT2,RGL1,NECAB1,DICER1,SLC44A1,TUB,ACTR3B" Coexpression M9403 Genes down-regulated in T reg: BCL6 [GeneID=604] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.57E-04 1.00E+00 6.59E-03 6.55E-02 30 106 "ACHE,ADARB2,DSCAML1,SYT13,NOG,GPR37L1,LHX2,COX4I1,ZIC4,TUBB4A,GRIK1,KCNH2,SAMD5,NPPA,SNTG1,GDPD2,ACSS3,RFX4,NEK11,SCN2B,TNFRSF19,HKDC1,PREX2,CAND2,C11orf87,ARC,ANO4,SEZ6L,FMN2,PAK5" Coexpression M7778 "Genes down-regulated in Rh4 cells (alveolar rhabdomyosarcoma, ARMS) after knockdown of the PAX3-FOXO1 [GeneiD=5077;2308] fusion protein by RNAi for 72 hr." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.59E-04 1.00E+00 6.59E-03 6.55E-02 17 48 "ABAT,ARRB1,CNR1,DZIP3,ZFYVE16,JAKMIP2,PIPOX,IQCG,VWA5A,MYCN,NELL1,NRCAM,NKAIN1,PDZRN3,ARHGAP26,ASTN2,AKTIP" Coexpression M6520 Genes up-regulated in patients at the incipient stage of Alzheimer's disease. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.67E-04 1.00E+00 6.59E-03 6.55E-02 85 390 "ARID1A,ADD3,BRAP,APOC1,APP,ASCL1,ZBTB10,RGS9,CFLAR,C5,CAST,TAOK2,CLU,QKI,CSF1,VCAN,TBC1D5,USH1C,TSPAN5,EDNRA,SGK2,TUBD1,EPS8,EFEMP1,POLR1B,FGFR3,FLNC,ARFGAP2,FYN,STAG2,ERAP1,INPP5K,USP19,MALT1,DBF4,GLI2,OS9,ADGRA3,LPAR4,RBPJ,IL6R,ITGA7,KTN1,LAMA2,MATN2,MBP,NAP1L1,NUMA1,OGG1,PAH,KCNK10,PC,SSH1,MED1,SNRK,PTH1R,ARID4A,RBBP6,PBRM1,EMID1,SGK1,SLC14A1,ARFGAP1,SMARCC2,FNBP1,ZHX3,NPAS3,SRPK2,ITPRID2,ERBIN,DIP2A,TACC1,FAM208A,DICER1,TGFBR3,TPD52,PDSS1,USP1,ZNF24,ZNF32,SYNC,CSDE1,SEMA3B,SSPN,DPF3" Coexpression M13639 Genes up-regulated in multiple myeloma (MM) bone marrow mesenchymal stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.75E-04 1.00E+00 6.59E-03 6.55E-02 23 74 "MARCH4,ADAM23,NRXN3,CLCN4,ZNF582-AS1,DMD,SEPT9,LMO2,CD200,CLDN11,SLC25A23,SLC22A23,VEPH1,RGS4,ATXN1,LINC01114,SAMSN1,INKA2,TLR4,FAM155A,KCNT2,SCG2,RGS7BP" Coexpression M12816 Genes down-regulated in MDA-MB-453 cells (class A ER(-) [GeneID=2099] breast cancer) after exposure to the androgen R1881 [PubChem=13766]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.75E-04 1.00E+00 6.59E-03 6.55E-02 57 241 "ACTN2,ASPH,ADGRB2,BCL7A,DST,CACNA1D,SLC25A14,CDC42,DCLK1,TBRG4,QKI,SIPA1L1,CTNND2,TCAF1,SNPH,HP1BP3,ABCC5,EDN1,EEF1A2,EFNB3,ENO2,EPB41L2,EPS8,FAM198B,EVL,FYB1,STAG2,PSIP1,KHK,KIF5C,MN1,PDE4B,PEX5,RAD51D,SUSD4,RGS10,FBXW7,WLS,RTN1,ATXN1,ASAP3,ABLIM3,PPP4R3A,IFT122,PALLD,PDZRN3,NCDN,SEPT8,PRRC2C,PLCB1,OBSL1,TIAM1,SSBP2,TUBB2A,NSD2,PRDM2,PCBP4" Coexpression M13276 Genes down-regulated by IL2 [GeneID=3558] in cells derived from CD4+ [GeneID=920] cutaneous T-cell lymphoma (CTCL). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.76E-04 1.00E+00 6.59E-03 6.55E-02 14 36 "ATM,CACNA1E,DAPK1,ING4,CACNG3,IP6K2,FOXO3,SESN1,RFFL,JAK2,SESN3,PDE3B,ENPP2,PLCB1" Coexpression M10412 Top 50 down-regulated genes in cluster PR of multiple myeloma samples characterized by increased expression of proliferation and cell cycle genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.77E-04 1.00E+00 6.59E-03 6.55E-02 16 44 "ALCAM,CNTN1,ANKRD44,SH3GLB1,GAB1,UBE2QL1,MAP2,DUSP26,PLCL1,SATB1,FGD4,SYNE2,DDHD2,TK2,PRDM2,JMJD1C" Coexpression M12490 Genes up-regulated in uveal melanoma: class 2 vs class 1 tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.77E-04 1.00E+00 6.59E-03 6.55E-02 155 782 "RALGAPA1,ABR,ACLY,SPARCL1,ALK,BIN1,OGT,CDC42BPA,ANK2,MAP4K3,APP,SHTN1,PDXK,ARRB1,RGS20,CAPRIN2,ASPH,ZBTB10,NUMB,ATM,EIF4G3,ATP2A2,ATP2B1,ADAM23,CDK5R1,LDLRAD4,CALM1,CBR1,CDC25B,CDC27,NPIPA1,ADGRG1,SRSF11,IFFO1,CDC42BPB,C2CD2,CREM,NCOR1,FEZ1,PDE4DIP,GREB1,DOCK4,DCAF8,HDAC4,DAPK1,PITPNC1,ZEB2,ZC3H11A,SACS,RABGAP1L,CASP8AP2,RCAN1,ANKRD46,FRY,PHF20L1,EGR3,PLXNC1,VPS13B,MFSD10,AMZ2,SH3YL1,TBC1D16,OLFM1,FGF13,BAIAP2,TMEM164,FHL1,SYNCRIP,FLNC,TACC2,FAM49B,ATP6V1H,TCERG1,COPS8,GNAS,PSRC1,ADGRA3,GPM6B,RAPGEF4,SYNPO,MSL1,IFI16,KCND3,KIT,MAN2A2,MARK3,MEIS2,PTOV1,MTR,MYO6,FXYD6,NASP,NF1,NME4,CNOT4,SLC11A2,NRDC,NUCB2,PCMT1,PDE4A,PFKFB3,PFKP,PIK3C2A,RETREG1,PKM,FAM216A,PLTP,PTPA,WBP1L,PTK2,PEX2,QDPR,RAP1GAP,RAP1GDS1,OXR1,RDX,REV3L,RPS6KA2,WLS,CLIP1,TRAPPC13,SFPQ,SGK1,RUFY2,SMARCA4,FNBP1,ZHX3,SPTAN1,CDK19,PRRC2C,SYNE2,ASTN2,MTCL1,CAMSAP2,ATMIN,TCEA1,TCF12,DOCK9,NACC2,RBFOX2,TPD52,TRIO,ZMYND8,TTC3,CADM1,UBE3A,MICAL1,VLDLR,WIPF1,REEP1,MAP3K12,LRP8,CERS6,JMJD1C,NETO2" Coexpression 18381423-Table1 Human StemCell_Riggi08_46genes GeneSigDB 5.84E-04 1.00E+00 6.59E-03 6.55E-02 15 40 "NLGN4X,LRRC4C,SYNPR,CSPG5,LINGO1,IGF1,JAK1,MAPT,NELL2,NKX2-2,NPTX2,NRCAM,PCSK2,NTNG1,SOX2" Coexpression M3971 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "DPF1,SLC25A25,APAF1,ASPA,ADAM23,GPR37L1,ABCG2,SLC4A8,HINFP,CSF1,FEZ2,G3BP2,RABGAP1L,DNM1,RASGRP1,RABEPK,ATP8A1,AMOTL2,FLNC,STAG2,TRAF3IP2,GK,SCIN,SMAD1,MEF2C,MPP2,GPSM2,USP47,RBBP8,RFX5,RGS10,LRRK2,FOXRED1,SH3BP2,ARX,CPEB3,FNDC3A,PEX26,KBTBD4,SOX10,DBNDD2,SSPO,RGL1,STXBP1,FBXW11,TCF4,MTMR14,C9orf85,TFIP11" Coexpression M4880 Genes up-regulated in comparison of neutrophils versus monocyte macrophages. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACADM,MTUS1,MARCH4,TRMT9B,CDK13,BBS2,CNR1,MAGED1,CSF3R,IPCEF1,SIPA1L1,ARHGEF4,ZBTB24,ABI1,YAF2,SH3GLB1,ING4,RCSD1,CACNG2,FCGR3A,FOXO3,DCTN2,FAM120B,SYT17,ARFIP1,NR3C1,AGBL5,LMO2,MBP,NFE2L2,SMOX,PDZRN4,STRN3,MAPK3,RAD51D,RAP1GDS1,ZDHHC4,ZFHX4,SHC4,SIRT2,ATF7IP,SON,FGD4,TACC1,EXOC7,AKNA,MGAT5B,BEST1,LGI4" Coexpression M7877 Genes up-regulated in B cells: light versus dark zone. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACLY,ELFN2,ADCY5,PDZD4,ARRB1,BTRC,CACNA1E,CCPG1,AKAP6,BAG4,OSBPL3,CTNND1,KIF26A,SV2B,ATN1,EDN3,OPTN,EFS,CACNG2,SDCBP2,INPP5K,WASF3,STON1,PTPN5,GSTM5,KCND1,LAMP2,INSYN2,MAP4,DDX25,NDP,NTRK3,P2RX7,GPR85,PLXNB1,SLC36A4,RAB3IL1,NUDT11,SLC30A10,TMEM132D,SYT1,KLHL4,TF,FBXL16,TIMP4,LMF1,ZNF711,RGS7BP,CERS6" Coexpression M9854 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "KIAA1211,LRFN2,AMH,KCNAB2,APP,ATP1A2,RGS9,MYRF,CANX,CCKBR,SLC5A11,CD38,DLGAP1,UBE2L6,ASIC3,CYBB,KIF26A,DNM1,USP3,DRP2,RASGRP1,SIRPB1,CACNG2,SEMA6C,ERAP1,DNER,GLI2,RNF165,HP,ITGAM,KCNC1,KCNMA1,SAMD5,NODAL,PKM,PILRA,POU3F2,FSD1,DEF8,C1orf54,KLHL11,FOXRED2,SEMA4A,TNNT1,TRPM2,CFAP298,CSDE1,ST8SIA2,PRRT4" Coexpression M7607 Genes down-regulated in CD11b+ cells from BALB/c mice bearing: C26GM colon carcinoma versus 4T1 mammary carcinoma. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ABR,CLK4,ADD3,ARHGEF1,CBFA2T2,SRSF11,FOXN3,ARHGEF6,MAML1,PITPNC1,ABI1,PLEKHA1,USPL1,PLEKHO1,EPB41,ATP8A1,POLR1B,EVL,MSL3,KLF12,MSL1,MAN2A2,MXI1,LYRM9,ZNF862,NACA,CCSER2,PPM1B,PRKCZ,WBP1L,SNRK,PTCH1,TMEM260,USP47,CASC3,TTC17,ANKRD36,SON,SPTAN1,FAM208A,CLASP1,SYNE1,FRYL,DICER1,TSC2,TTC3,UBE2H,ZNF32,MPPE1" Coexpression M5085 Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "KLHL32,APP,TMEM108,RGS11,CD81,LRBA,MAP4K4,NIPBL,PUM1,ARMCX2,FAM107B,NR1D2,EFNB3,C8orf37,CALCRL,RCAN2,CD320,ARMCX1,ST3GAL6,PRMT5,FGF11,MEX3B,FOXO3,HVCN1,IQGAP2,PADI2,MIER3,KCNH2,SYTL4,MYO7A,NME4,PCSK2,TMEM38A,POU6F1,MTMR10,MSANTD2,RFX3,ATP8B4,STK32B,DGLUCY,DOCK10,TRIM67,SYPL1,DNMBP,SYNE1,HEY2,WNK1,CERS6,RSPRY1" Coexpression M5063 Genes down-regulated in comparison of CD4- [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ABHD6,ADD1,ESYT2,PPFIA4,DGKZ,MADD,ARRB2,CLCN4,RNF14,NCOR1,LRIG1,DOCK2,IRAK4,ENO2,ETV1,PTK2B,EVL,MALT1,LYVE1,POLL,GSN,JAK2,GPR155,SESN3,NTRK2,NUCB2,PCSK1,PDE3B,PIK3CD,SIDT1,MTMR10,RFX4,GALNT10,SLN,SON,SPTAN1,KIF1B,VAMP1,PJA1,IQCE,TNFRSF1B,CABIN1,PRMT8,UBE2H,WIPF1,MEIS3,WNK1,MPPE1,ADAMTS10" Coexpression M4822 Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "NDRG3,ADCY6,ADORA1,BIN1,LRCH2,DGKZ,TNRC6C,CDK10,RGS20,CNR1,SLC4A7,RNF14,NCOR1,TCAF1,ASB3,PAN3,EPB41,SUCO,IP6K2,GABRG1,ATP8A2,GBX2,ADAMTS8,GRM5,KIF3A,FAM222A,AGFG1,KCNC2,SESN3,FXYD6,NDP,PDE2A,TTC13,CCDC82,SUPT20H,SCG5,SLC6A7,SNRPN,SP4,PJA1,ADGRL3,TCF12,GPRIN3,DNAH7,METTL3,ZMYND8,CA14,MEAF6,ZFP41" Coexpression M5983 Genes down-regulated in liver with knockouts of: SOCS3 [GeneID=9021] versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TTYH1,AS3MT,C3orf14,ADORA3,BCAR3,ATP6V1G2,RGS11,PROM1,PRC1,FAM149A,TENM4,TOMM20,SIRPA,CDON,PLEKHA1,ST3GAL6,MED12L,UBE2E3,NSG2,ACSS1,HPGDS,GPM6B,GPR34,GSTT2,STMN1,LDLRAD3,AFDN,MRPL42,BLOC1S2,NPR2,PC,ANLN,C11orf49,SLC36A4,SLC22A23,ZDHHC14,RNASEL,TMEM100,DGLUCY,CLSTN1,SLC12A2,KIF13A,TMEM151B,ARHGEF12,AHCYL2,TNNT1,MEIS3,ITM2C,PLD4" Coexpression M5691 Genes down-regulated in comparsion of ActTreg versus ActCD4 (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ADCY6,RNF157,RNF150,AP2A1,AGT,APP,PDXK,CACNA1G,NIPA1,CAMK2G,SEC24C,SIPA1L1,CTNND2,TMEM170A,SPOCK2,SEC16A,TSPAN5,ELAVL3,C8orf37,RASL12,RACK1,AGAP2,KIF3A,LIX1,KCNK1,KIFC3,PACRG,MIA2,OGDH,PDE3B,PLXNB3,STRC,RASGRF2,CCDC25,BEX1,TSPYL2,NPAS3,TBL1X,VWA3A,WSCD1,WASHC4,TMEM121,TNNT1,PIK3R5,MGAT5B,SPHK2,SLC30A4,SIGLEC10,SSPN" Coexpression M5453 Genes up-regulated in comparison of mast cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "NR0B1,MARCH3,SLC2A11,BCS1L,CACNA1I,CA12,NPIPA1,HOMER3,SOCS5,CTNND1,ZNF337,TBC1D5,SPATA2,ZNF804A,SIRPB1,CHST15,CAMSAP1,B3GAT1,ZMYND11,GALC,GLUL,GNAS,HNMT,HP,MEIS2,MT1M,NFE2L2,OPRL1,TREM2,PILRA,PTAFR,PTK2,HUNK,FAIM2,DOP1A,ZHX3,EPB41L3,GSE1,CAMSAP2,AHCYL2,HEY1,TMOD1,ZMYND8,ZIC3,ZNF24,ZSCAN26,PMEPA1,MVB12B,MARCH8" Coexpression M6310 Genes down-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 3h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TBC1D14,NR0B1,CACHD1,TMEFF1,CA12,CAPN3,CHGB,RBM39,CRMP1,RNF14,GPRASP1,ENO2,MED12L,FGF12,SPECC1,GAB1,GABRB3,TRAF3IP2,INPP5K,TUBGCP4,PPARGC1A,SYT9,CHIC1,AFF1,COMMD5,NEK1,NNAT,SETD4,OGDH,SERPINI1,PMS2,PKIA,MAPK10,ELOVL2,PTK2,PTX3,RAD52,WLS,SCAF8,FHOD3,SRPK2,SMOC1,DICER1,SLC44A1,BEX4,SLC35A4,ZNF23,ST7,JPH3" Coexpression M3529 Genes up-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "FAM43B,ERMN,PWWP2A,PPFIA2,ALDH7A1,RGS11,BAIAP3,VSTM2A,DCLK1,EVI5L,TMEM184B,CNRIP1,CSNK1E,OSBPL3,GALNT9,CX3CR1,SPOCK2,SRGAP3,TSPAN5,C8orf37,RPS6KC1,BAIAP2,STAU2,GPM6B,IGF1,KIF5C,LMO1,SRSF12,MITF,MT3,PCBP3,PLTP,PURG,NKAIN4,PLEKHB2,KIF7,TMEM206,RPS6KA2,TET1,GKAP1,TROVE2,ACSBG1,TNS2,TEX15,LEFTY2,TOM1L2,NPDC1,NDRG4,PRDM8" Coexpression M8339 Genes down-regulated in BCL6 [GeneID=604] low follicular helper T cells versus naïve CD4 [GeneID=620] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ABAT,SLC12A5,OSBPL8,SPARCL1,ATP1A3,NOL4,BARD1,CDK5R2,NIPBL,CSF3R,SUSD5,ATRNL1,BRINP1,DMPK,ELAVL4,F3,FKTN,FDFT1,FLT1,DKK3,GCNT2,HPGDS,GRIK1,PTPRT,KIF3A,RBPJ,ITPKB,KCNN3,MID1,PCSK1,ST8SIA5,SMOX,WBP1L,PTPRN2,SBF1,SLA,SMTN,EMC1,DDN,EPB41L3,ZFR2,SYT1,TCF4,WASHC4,RBFOX2,TOM1L2,ZIC3,NDRG4,SLC26A10" Coexpression M5747 Genes up-regulated in comparison of lymph node conventional T cells versus fat tissue conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ADAR,GPRASP2,ARRB1,BCS1L,GPR146,CAPN3,ZNF445,BTF3L4,AKAP5,PREPL,FBXL5,MTX3,E2F6,AASDH,GAA,AHCYL1,TUBGCP4,SESN1,RAPGEF4,INPP5B,SESN3,TMIE,FTO,POU3F2,PPM1B,CEP41,PRKCB,PTCH1,REV3L,RFX3,EXD2,ZNF354C,DGLUCY,SATB1,HES6,EMC1,RBM26,COLGALT2,ERBIN,NCDN,SPX,ITGB3BP,TGFBR3,LRTM2,SGK3,PARP11,CERS6,RNF170,SOCS4" Coexpression M8208 Genes down-regulated in germinal center B lymphocytes: control versus over-expressing PRDM1 [GeneID=639]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ALCAM,ANK3,CAPRIN2,SLC4A4,ATP2A2,SYNJ2,MAP7,CFL2,ADGRG1,CHGB,MFSD4A,TOMM20,ARMCX2,C8orf37,EPS8,ST3GAL6,AMOTL2,TRAF3IP2,NCKAP1,GHR,GLRB,HSP90AA1,SCIN,CHIC1,CD200,MYO6,NDUFA5,SMIM11A,PBX1,PENK,RETREG1,CDIP1,PMS2,EPB41L4B,TUG1,BSDC1,WLS,RYR3,SLC6A8,SCMH1,LIMCH1,WWC1,ZNF106,SLC44A1,THRA,CA14,AMOT,VLDLR,NAV2" Coexpression M5707 Genes down-regulated in comparsion of sfActCD4 versus WTActCD4 (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "USP28,CAPRIN2,COL11A2,BAG4,ZNF521,FAM169A,CALY,GREB1,LONRF1,DLG3,FEM1B,MRO,GPHN,SRRM1,NRN1,FGF13,SYNCRIP,ZNF605,ST6GALNAC3,ADGRA1,DBF4,EML4,UBE2QL1,IGSF21,AGBL5,IL6R,BRINP3,IPO5,HECTD2,PTOV1,MDGA1,NFIX,PC,PSD,C1orf109,RASGRF1,SMPD3,SLC4A3,YPEL4,MAPKBP1,SNRPN,KANK1,SATB2,TCF7,ZNF106,TPD52L2,RASD2,STXBP4,SLC26A10" Coexpression M4667 Genes down-regulated in comparison of untreated CD8 T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ZNF608,TBC1D14,C1QTNF1,FAM135A,SLC7A14,NCOA1,CH25H,CDO1,LY86,MAGED1,FEZ2,RIPOR2,ARHGAP24,RHOBTB1,MED12,EBF1,ATL1,KCTD3,SORBS3,GTF2IRD2,CAMSAP1,ARFGAP2,SARAF,ZNF512,FAM120B,ZMYND11,SRCAP,USP19,PRDM5,PSIP1,MAN1B1,IGSF1,MBP,POC1B,FXYD7,PDE3B,PKD1,PRKAB2,PRKACB,PRKCB,QRICH1,EML5,ROGDI,LRRK2,SH3BP2,SLC4A3,ATF7IP,ZNF708,PIANP" Coexpression M3587 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ADRB2,MAP4K3,APC,APP,SEC11C,FOXK1,HIP1R,MAP7,ARHGEF25,CCKBR,USP2,MYOM2,AKAP7,ABCG1,IP6K1,DLX1,USP3,SUGP2,TLR7,UBE2E3,FUT9,GABBR1,INPP5K,GNG3,CNTRL,RAPGEF4,COQ10A,INSM1,KCNH2,LMO2,SYT9,MEST,KITLG,MX1,MYH7,PDE4B,PKD1,SPATA6,RETREG2,RAB5B,PLEKHB2,BSDC1,ZYG11B,RFX2,SP4,ST5,MAPK8IP3,EXOC7,TEK" Coexpression M5124 Genes down-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "SLC12A5,AP2A2,C1QTNF1,APAF1,KCNAB2,APBB2,NCOA1,C1QC,AP1M1,TRIM41,HOMER3,RGS6,CST3,MYADM,DCC,DOCK2,EIF4G1,BSCL2,ZIC4,MED12L,ERGIC3,CHL1,GFER,DHRS4,GLRB,MAN1B1,HNRNPK,KCNA2,KCNH2,MBP,MEIS2,MID1,SFR1,ANLN,SCHIP1,PTPRG,PTPRN2,PBRM1,RPE,TNFRSF19,ARX,KIF16B,TET1,SOX11,MPRIP,TJP1,EIF4ENIF1,AMOT,ZFP37" Coexpression M9130 Genes down-regulated in T reg: IKZF4 [GeneID=64375] versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ABHD6,RNF157,MTA3,PITPNM2,TNRC6C,CPNE5,CDK13,NCOA1,MAP7,LY86,SIPA1L1,TBC1D5,GIT2,PITPNC1,ELMSAN1,DMPK,WDPCP,OPTN,PAN3,RCSD1,ATP8A1,ANKFY1,ZBED3,STAU2,CECR2,ATE1,GSN,BACH2,LRRC75A,LRRCC1,PRKCB,CNTLN,PTK2,REV3L,EPC1,GKAP1,LHFPL4,ZBTB43,MPRIP,ADHFE1,STXBP1,CAMTA1,FAM208A,KIAA1107,KIAA0930,VAV2,ZBTB14,TUBA1A,GOPC" Coexpression M9361 Genes down-regulated in day 7 germinal center B cells versus day 7 plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TXNDC16,BIN1,MYOM1,BCL2L2,SPAG9,CD86,QKI,AKAP7,CTH,CTNND1,MYADM,PLEKHM1,RHOBTB1,ATL1,OPTN,COQ7,PCYOX1,POMT1,TVP23A,TOX2,CFAP126,KTN1,PIK3AP1,SESN3,BLOC1S2,CYTL1,PCDH18,DRAM2,PRKAB2,CNNM2,RAD17,ROGDI,ARID4A,BEND5,GTDC1,PTGR2,SH3BP2,MYO18A,ZNF667,ZFP90,VWCE,ANKRD24,DCBLD1,TSC1,AMOT,ZNF213,PHTF2,JMJD1C,DPF3" Coexpression M9255 Genes up-regulated in dendritic cells: hydrogen peroxide [PubChem=784] versus diphenyleneiodonium (DPI) [PubChem=2733504]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ARID1A,ADD3,AMPD3,MAP4K3,MIER1,TMEM108,GPR146,CFLAR,MTMR2,CFL2,RCBTB2,CNN3,SLC25A27,COL11A2,VCAN,GAPVD1,MAML1,NR1D2,ATN1,EEF1D,CALCRL,ATP8A1,ACSS1,SESN1,NR3C1,ZBTB49,PADI2,IL6ST,DIPK1A,SPATA6,PPM1B,PPP3CA,PSD,PTK2,TMEM206,ZNF354C,SATB1,GALNT10,SGK1,FAM102A,DZIP1,TET1,ZFP1,PIK3R5,TP53BP2,RUNDC3B,AMZ1,PPP1R3F,KLHDC1" Coexpression M5508 Genes up-regulated in comparison of macrophages versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "AMPD3,PDXK,NUMB,ATP2B2,CBR1,REPS2,ARHGAP22,ABCG2,BAG4,CSF1,APPL1,USP6NL,ZNF804A,CEP170,PLXNC1,KCTD3,PCOLCE2,BSCL2,EPB41L2,ZNF589,FER,ATP6V1H,GATM,GK,GPER1,EML4,GSN,ACOT7,RBPJ,MKLN1,MSRA,MYO5A,ENPP2,SMOX,PMP22,PTK2,MARCH1,RXRA,STUM,SLC2A5,ARHGEF40,ITPRID2,EPB41L3,STXBP1,NACC2,BEX4,TNS1,UCHL1,DNAJC12" Coexpression M3450 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus thymic stromal cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "BCHE,RAB29,RUNX1T1,CDH2,LARGE1,SLIT2,KIAA1549L,TMEM184B,HOMER3,CNN3,COL4A5,NECTIN3,TENM4,ARMCX2,DNAJC6,CEP170,EDNRA,EDNRB,F3,RPS6KC1,TBC1D16,CORO2B,FKTN,STON1,GSTT2,KCNK1,LAMP2,TM6SF1,MYO6,MBOAT7,ZNF532,TMEM100,RPS6KA2,SYNDIG1,DZIP1,SLC6A1,SLC6A8,ZCCHC24,DOK5,BEX1,SS18,RGL1,PDLIM2,ARHGEF12,TGFBR3,NACC2,RBFOX2,TUBB2A,NPDC1" Coexpression M4971 Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACTN1,NDRG2,APAF1,GAS7,ARRB1,ATP2B1,CD86,RCBTB2,LY86,COL9A2,C2CD2,CSF1R,VCAN,CST3,SIRPA,PLXNC1,EPB41L2,IGSF6,FGR,EVL,FYN,MTHFD2,ADAM28,IRAK3,PADI2,ELOVL5,RBPJ,LIMS1,P2RY13,NCF2,PILRA,PID1,RGS10,RNH1,ATP8B4,RTN1,SEC14L1,SGK1,SH3BP2,GSE1,SEMA4A,AGTPBP1,TBL1X,NACC2,TRIO,TST,LAT2,TUBA1A,NLRP3" Coexpression M9354 Genes up-regulated in heterozygous knockout of BCL6 [GeneID=604]: follicular versus marginal zone source. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "AS3MT,AMPD3,DGKD,DOCK11,AP1M1,SPAG9,FMNL3,ZNF445,B4GALT6,TPP1,TJP2,CSNK1E,RIPOR2,ALKBH8,WDPCP,SLC43A2,CDKL3,RACK1,FLYWCH1,TMEM175,FAM120B,INPP5K,ACSS1,DBF4,GSN,FICD,KLRC2,L1CAM,ZFYVE27,SESN3,ADAM22,MAPK7,RPL38,RTN1,DGLUCY,SLA,ZCCHC24,MYCBP2,ARHGAP26,SRPK2,SUPT5H,VAMP1,PDLIM2,SZT2,ARHGAP9,CELF4,EML6,C12orf4,TTC7A" Coexpression M9188 Genes down-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus LEF1 and FOXP3 [GeneID=51176;50943]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACTN1,ACTN2,NDRG2,GALNT16,ADCY6,ADD1,DGKD,SFMBT2,RASL11B,NRP2,BTK,HAP1,FMNL3,EVI5L,KIAA1549L,DLG3,SLC12A6,RASGRP2,PRAM1,TACC2,GALC,ARPP21,TCERG1,KCNMB4,GSTM5,ZDHHC15,MSL1,KTN1,STMN1,AQP11,TM6SF1,CPNE9,PCSK1,PPM1B,PPP1R1A,PYGM,RPRD1A,SLC30A10,FOXRED1,DZIP1,TNIK,SEMA4A,MCF2L,KLHL4,TCF7L2,TTC3,SMARCAD1,PARP11,AAAS" Coexpression M6424 Genes up-regulated in monocytes in response to M. tuberculosis 19 kDa lipopeptide: 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TMCC3,SLC12A5,AP1M1,DDR1,ENTPD6,REPS2,ZNF445,SLC4A7,COX4I1,KBTBD11,CD99L2,ABI2,LPAR6,GPHN,EVL,TPK1,MALT1,HPGDS,MSL3,RAPGEF1,PSIP1,ARHGAP19,MSL1,IL6ST,INPP5B,PIK3AP1,MEIS1,KCTD6,ADAM22,CDK14,PRKACB,MAPK8,SLC22A23,ROGDI,BEND5,RGS12,CLIP1,CASC3,CCDC88A,SULF2,ATMIN,TCF7,NSD1,CYB561A3,SMUG1,SGK3,UGT8,TMEM178A,ITM2C" Coexpression M8538 Genes up-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACTN2,PLEKHH1,CNTNAP1,PDXK,MPDZ,RGS11,HCN2,C1QC,CDK5R2,GPR37L1,FOXN3,NMT2,ZNF385A,VCAN,NRSN1,DAPK3,DLG3,USP3,EFNA2,FGF1,NEURL4,GGT5,RUNDC3A,CIT,IL12A,KCNB1,KCNH2,LMO2,MEIS2,AFF1,NCAM1,NPPA,DDR2,NUCB2,SETD4,SEMA5B,PIK3C2A,PRKCZ,NKAIN1,RXRA,SELL,SNCA,CUX2,TRH,ELP5,WNT7A,ZNF213,MAP3K12,SHD" Coexpression M363 Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TMCC3,ADRB2,BEND6,AP2A2,KALRN,PTBP2,CD86,CNRIP1,PNPLA8,RIPOR2,DPH1,SNX29,GPHN,SCML2,ATP8A1,MEX3B,FOXO3,ZNF512,GAB1,PSIP1,MIER3,HLF,SLC35G1,KIF2A,MN1,NAP1L3,PDCD2,RETREG1,SLC36A4,LRRC49,CNTLN,TUG1,ZC3H14,AMER2,DZIP1,CLSTN1,KANSL3,UHRF1BP1L,CDK19,PBLD,PSD3,ATP13A2,TPD52,RFTN2,RICTOR,ZSCAN26,SLC30A4,KAT6A,ADAMTS10" Coexpression M5713 Genes up-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "FMNL2,ADARB2,ADORA1,CC2D2A,NT5C3B,ASPH,TMEM108,BBS2,NRP2,DIRAS1,CIART,CCDC151,SLC35F1,RGS6,KIAA0040,NOS1AP,ARHGAP24,PHF19,HP1BP3,EPB41,LRRC17,CSPG5,KBTBD12,ADGRA1,GFAP,GJB1,GPR19,STMN2,IRAK3,INSYN1,MYLK2,CREG2,NCOA7,SCAMP5,RTL5,OGG1,PDE3A,ENPP2,GPR85,C11orf49,ZIK1,SEMA6D,DRAXIN,SMARCC2,ANKRD12,TBL1X,TJP1,EIF4ENIF1,GJC2" Coexpression M3357 Genes down-regulated in comparison of Th1 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "RBM10,TBC1D14,SMIM17,APBB1,BARD1,SYT6,KCNAB3,AKAP6,ERC2,PNPLA8,PYGO1,GIT2,HEYL,CALCRL,SCML2,NELFCD,KBTBD12,C15orf41,GJB1,GOLGB1,BVES,HPS5,NCKAP1L,SMAP1,IDH3A,KHK,KTN1,STMN1,AFDN,CCDC80,DDX25,NPTX1,ENPP2,PILRA,GDPD1,FAM120C,ELMOD1,COPZ1,DNAJC9,MTMR14,ERCC6L2,HEY2,SYNPO2,HEPACAM,VLDLR,MFF,PLSCR4,GJC2,SLC39A12" Coexpression M5719 Genes down-regulated in comparison of CTRLrv versus FOXP3rv (see Fig. 1 for details). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "DSCAML1,AGT,INSYN2B,ALDH7A1,CFAP410,CAPN3,SLC5A11,CD81,SH2B1,CSNK1G3,PPP1R16B,TMEM130,ZC3H11A,GPHN,EFS,F5,WAC,CHST15,SARAF,HHIPL1,GALNT15,HPGDS,GRK4,ADAMTS6,MAP4K5,HLF,LRRCC1,IL6ST,HECTD2,LYPLAL1,OPHN1,FAM120C,RASGRF2,RFX5,SMPD3,AMBRA1,SLC9A5,ABTB1,PALLD,DBNDD2,PSD3,CYB561A3,SLC44A1,TK2,TST,EVI5,ITM2C,ACTR3B,FRMD6" Coexpression M7863 Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus IL1B and IL6 [GeneID=3553;3569]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACHE,SFMBT2,ATP1B3,BCS1L,DCLK1,TJP2,FADS2,CHD1L,GDA,MICAL2,ARHGAP24,BLOC1S6,RPS6KL1,CELSR3,OLIG2,EXTL1,POLR1B,SPSB4,FAM184B,NCKAP1,MYOZ2,MCHR1,HAS2,KCND3,KITLG,NEXMIF,MYT1,NDP,NF1,ENPP2,PFKFB3,CCSER2,RETREG2,PPM1B,PTX3,OXR1,MORC4,RYR3,KIF16B,CCDC88A,SLC12A2,NAPB,LIMCH1,SNCA,USP33,BEX1,KIF1B,TCF7,TRH" Coexpression M8042 Genes up-regulated in CD8 T cells stimulated by IFNA2 [GeneID=3440] versus those activated by anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "RALGAPA1,MTUS1,SYNJ1,ST3GAL5,LRBA,CCPG1,RAB33A,BAG4,SEC31B,IPCEF1,RUBCN,GPRASP1,GAPVD1,RIPOR2,ZFYVE16,PITPNC1,ARMCX2,FBXL5,OPTN,DENND4A,TAOK3,FKTN,ZNF274,DIPK1A,KLRC3,ARHGAP12,NELL2,OGG1,PDE3B,ENPP2,SERPINI1,PIK3C2A,RAB5B,ZNF493,MSANTD2,GTDC1,ROBO1,CCDC25,CLIP1,AP1AR,ATXN1,URGCP,RAB3GAP1,SMARCD3,TTC17,DOP1A,KIF21B,WIPF1,ZNF189" Coexpression M3932 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ADD1,AP4M1,MAP4K4,CNR1,COL11A2,TRIM69,MAML1,DGKG,ARNT2,CD99L2,EBF1,SNX29,EN2,RCAN2,KCNMB2,EXTL1,CHST15,INPP5K,GGT5,HPGDS,GPR37,PTPN5,MDFI,MEIS1,RSPO2,MYO6,FXYD7,DDR2,ZNF426,TNPO2,PSD,CLIP1,SATB1,ATXN7,ZFP30,FAM81A,CDK5RAP3,RCOR3,WDTC1,EPB41L3,MLC1,RHBDL3,SYN2,TNS2,THRA,TPM2,PCDH20,NT5M,SLC17A6" Coexpression M291 Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from lymph nodes: mesenteric (mLN) versus peripheral (pLN). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "RBM10,RNF157,AP2A2,MTMR9,ADGRB2,FOXN3,CLCN3,GAL3ST1,CTNND2,GPSM1,MAML1,ELMSAN1,KBTBD11,ABI2,APC2,TBC1D16,CHST15,SEMA4D,C2orf88,TRAF3IP2,TNRC6A,PTGDR2,BACH2,KCNJ5,PIK3AP1,NDP,OPA1,PDE2A,MED1,PRKCB,UHRF1BP1,TTC13,ATXN2,ITSN1,ST8SIA1,DHX30,ATF7IP,LGI3,TMCC1,SEMA4A,TBX15,KIAA0930,ZEB1,TIAM1,CADM1,DHX33,WNK1,PRDM2,SLC38A1" Coexpression M7965 Genes down-regulated in wildtype bone marrow-derived macrophages treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ASIC1,ADORA2A,AMPD2,SEC11C,CIART,MYL6B,TRIM69,SDC3,KIAA0040,DOCK4,DAPK1,YTHDC1,DCTN1,MTX3,TOM1,SUGP2,TNK2,EYA1,ARMCX1,SUCO,CAMKK2,NSG1,GUCY1A2,ITGAV,LYRM9,NDUFA5,NFIA,PDE1B,PFKFB2,SSH1,LRRN3,CCDC40,SLC25A36,SUGCT,SEMA6D,DOP1A,SON,TNIK,STX1A,ZFR2,ROBO3,MCF2L,HIF3A,DDHD1,STXBP4,DCBLD1,TTC3,TMEM198,CAB39L" Coexpression M8541 Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "TXNDC16,ALCAM,BIN1,BTK,CD38,RAB28,LY86,SLC4A7,ZNF385A,AKAP12,RASSF2,IST1,RCAN1,DYRK1A,EIF4G2,ING4,SRPK3,EPB41L2,CORO2B,FCGR1A,FAM49B,HBS1L,STARD10,CPLX2,FICD,INPP1,KTN1,MEF2C,MYO5A,NCF2,NUCB2,PCSK5,PLEKHB2,ATG16L1,ZDHHC14,RGS4,SLC25A36,ZNF532,SAFB,MAPK12,SELL,MYCBP2,GANAB,SYPL1,TCF4,SLC44A1,TK2,C9orf85,EVI5" Coexpression M5473 Genes down-regulated in comparison of dendritic cells (DC) versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "BRAP,SPOP,BEGAIN,CAPRIN2,BTK,OSGIN2,REPS2,CHN1,CNOT8,ARHGEF6,MYRIP,OSBPL3,ERC2,GIT2,PITPNC1,KBTBD11,MAMLD1,EIF1,TMEM164,MALT1,BRD8,DIDO1,PTGDR2,BACH2,HSPA1L,LINC00667,KIF5A,MEIS2,THYN1,NUCB2,PDE4D,NLGN3,DPF2,UBR7,SLC25A36,SUPT20H,FRMPD1,R3HDM2,SMARCC2,KIF21B,GLT8D1,TAL1,WSCD1,ZEB1,SYNE1,TMOD1,ZMYND8,LAT2,ZNF142" Coexpression M3440 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ABAT,ACTN1,AGT,OSBPL8,PLA2G4C,ADAM23,ST3GAL5,RAB29,CACNA2D2,ARHGEF6,RASSF2,SPOCK2,G3BP2,TENM1,PLEKHA1,RASGRP2,NCALD,ZNF589,TPK1,SARAF,GRB10,BACH2,IL6R,IL6ST,INPP5B,ITPKB,JAK1,KCNH2,CD200,NELL2,OMG,PDE4B,ABCB1,RETREG1,LRRN3,PTCH1,PTK2,FAM184A,RGS12,SATB1,SGK1,FAM102A,ST6GAL1,KDM4B,CAMSAP2,SATB2,SYNE1,TNFRSF1B,VAV1" Coexpression M3593 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with antigen-B7-1. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "BRAP,ADRB2,MAP4K3,APP,SEC11C,FOXK1,HIP1R,MAP7,ARHGEF25,CCKBR,USP2,CLTB,AKAP7,ABCG1,IP6K1,DLX1,USP3,ACOT8,EEF1A2,SUGP2,F3,UBE2E3,GABBR1,INPP5K,GNG3,CNTRL,RAPGEF4,PRDM5,COQ10A,INSM1,KCNH2,SYT9,MX1,MYH7,PDE4B,PKD1,SPATA6,RETREG2,RAB5B,PLEKHB2,BSDC1,ZYG11B,RFX2,RGS3,RPS6KA2,ST5,MAPK8IP3,EXOC7,CLIP2" Coexpression M9411 Genes down-regulated in NK cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ACTN1,MTMR3,MYRF,AKAP12,LRIG1,CSNK1E,SNPH,ZFYVE16,RIMS3,SV2A,EIF1,ST3GAL6,CHST15,FOXO3,IQGAP2,GLS,STARD3,LILRA2,NR3C1,GUCY1A1,LIG4,LMO2,SMAD1,MEF2C,AFF1,MXI1,NFYA,PDE4B,SERPINI1,RETREG1,SCHIP1,PPP3CC,PTPRE,RFX5,SATB1,SLC2A5,FAM214B,TMCC1,NPAS3,MAPK8IP3,CEP68,TTBK2,RGL1,COBL,DMXL2,WASHC4,PSD3,ZNF32,RNF103" Coexpression M7022 Genes up-regulated in IKZF1 [GeneID=10320] knockout: hematopoietic stem cells versus granulo-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "OSBPL1A,BIN1,SEMA7A,PRX,MARK4,ATP6V0A1,LDLRAD4,CERS5,MTMR7,CHM,TMEM184B,LRIG1,PDE4DIP,PUM1,SACS,WDR20,CPEB2,TSPAN5,RBM12,YAF2,ACSL4,SYNCRIP,SYT3,GABBR1,NEK6,GLUL,LPAR4,ATE1,KIF3A,RBPJ,L1CAM,LAMP2,ARHGAP12,STRN3,GDPD1,WBP1L,RAD52,ARHGEF10L,ZFP2,FAM102A,RUFY2,FAM214B,FAM126B,KDM3A,NEK4,SYP,SLC44A1,TRPS1,ZDHHC20" Coexpression M9298 Genes down-regulated in Lung dendritic cell from untreated IL-1R mice versus Lung dendritic cell from Ad5 T424A hexon inf IL-1R mice. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ARRB1,MAP7,RGN,TJP2,PNKD,GDA,CLIP3,LRRC3B,CTH,KATNAL2,DGKG,KMT5B,MRPL10,DUSP27,ECSIT,REEP2,FAM120B,KIF3A,CELF3,KCNH1,MSRA,NTRK3,OXTR,TMIE,PKM,NLE1,PLXNB1,SCHIP1,PTPRN2,C1orf54,FIGN,LRRTM4,TNFRSF19,IL17RB,ARHGEF40,SLC20A2,MYO16,ATP10B,USP22,PCDHB10,TF,TST,TBC1D15,CLIP2,ZIC1,ZNF142,ZNF189,MDH1B,TMEM63C" Coexpression M5545 Genes down-regulated in comparison of B cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "DPF1,ASTN1,CDH8,LRRFIP1,GPR37L1,CHN1,NRXN1,WHRN,NECTIN3,MICAL2,KLHL3,FCF1,SORBS3,MTSS1L,DLC1,GABRA3,SEPT9,RUNDC3A,PCLO,GRM5,KLHL23,KIT,MAG,MBP,MSR1,NPR2,P2RY1,SMIM7,MTRF1L,C11orf49,ING3,PTPN13,RASGRF1,PRR5L,SATB1,SLC14A1,KIF21B,KIF1B,FAM168A,CAMSAP2,ACSL6,TCF7,DNAH7,ZNF34,TNS1,TPM2,RUSC1,PDIA2,MVB12B" Coexpression M9765 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c int CXCR5+ [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 5.89E-04 1.00E+00 6.59E-03 6.55E-02 49 200 "ARID1A,NDRG2,ADD1,CARNS1,MAP4K3,USP28,BCAS1,ARHGAP5,NCOA1,ALDH4A1,BBS2,ARHGEF1,ACBD5,CLOCK,IP6K1,DCC,ARMCX2,CD99L2,NR1D2,DOCK2,EIF4G2,EZH1,FGF13,FOXO3,PDLIM5,PTPN5,MSL1,TUBB2B,SERPINI1,PKD1,SLC25A23,SLC26A11,RASGRF2,ARID4A,RGS10,MAPK12,RASA3,SCAF8,ST8SIA1,KIF21B,IZUMO4,SPTAN1,THRA,PIK3R5,ZKSCAN5,VAV2,PARP6,ZDHHC20,SNX14" Coexpression 18410693-TableS8 Human Leukemia_Kiiveri08_100genes_TEL-AML1Tree GeneSigDB 6.01E-04 1.00E+00 6.72E-03 6.68E-02 20 61 "CPNE2,HAP1,B4GALT6,ABCG2,ARHGEF4,CALN1,NRN1,FYB1,IQGAP2,PCLO,KCNN1,STMN1,NOVA1,PRKCB,EPN2,SLC12A2,ZNF423,ARHGEF12,TNS1,SH3GLB2" Coexpression 17009876-tableS3a Mouse StemCell_Ramos06_206genes GeneSigDB 6.13E-04 1.00E+00 6.84E-03 6.80E-02 44 175 "RBM10,AXIN2,TBC1D14,ANK1,MTMR9,BACH1,CACNA1E,CAMK2A,RAB33A,CLCN3,CNGA3,NECTIN3,C2CD2,CST3,SIRPA,TIAM2,G3BP2,DOCK2,EPS8,VPS26C,F8,FGF1,NEK6,AGFG1,LIFR,MEF2C,GIT1,MYO9A,NFIA,PDPK1,PLCD1,PLEC,PMP22,STX1B,ITSN1,ST6GAL1,KDM3A,TAB2,FRYL,LEFTY2,TPM3,TRO,ZBTB14,EVI5" Coexpression M8903 Genes up-regulated in CD4 [GeneID=920] versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 6.13E-04 1.00E+00 6.84E-03 6.80E-02 41 160 "SERPINA3,ADCY6,UNC5A,SPOP,APP,RGS11,DDR1,HS3ST5,RIPOR2,DNAJC6,LRRC23,RASGRP2,PCYOX1,TACC2,GABRA5,GGT5,RAPGEF4,PADI2,MAN2A2,MSRA,N6AMT1,PDE3B,PFKFB4,TMIE,SLC26A11,ZFHX4,RAVER2,ATP8B4,CLIP1,SCP2,GALNT10,SGK1,ST8SIA1,PEG10,SLC37A2,SEMA4A,TCF7,TGFBR3,NR2E1,PIK3R5,DOK6" Coexpression 17471573-Table2 Human Viral_Santegoets07_103genes GeneSigDB 6.23E-04 1.00E+00 6.94E-03 6.89E-02 26 88 "CDC7,BLM,DST,SGCE,CAPN3,SCARB1,SLIT2,FEZ1,CASP8AP2,EDN3,EDNRA,EDNRB,FGFR1,DKK3,GHR,IGF1,ITGA7,KIT,DDR2,EPDR1,PTN,ADGRL3,ITGB3BP,TGFBR3,SSPN,NETO2" Coexpression M8916 Genes down-regulated in Caco-2 cells (intestinal epithelium) after coculture with the probiotic bacteria L. casei for 2h. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.23E-04 1.00E+00 6.94E-03 6.89E-02 26 88 "PPFIA1,GYG2,CLCN4,CLU,QKI,MAP4K4,RCHY1,MICAL2,TCAF1,ZFYVE16,DBN1,GOLGA7,EFCAB2,UFM1,ATP2C1,DKK3,BRD8,FERMT2,KLC1,OPA1,KLHL7,TAF9,ZMYND8,CADM1,UBE3B,JMJD1C" Coexpression M3898 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.48E-04 1.00E+00 7.21E-03 7.16E-02 102 485 "ACADM,CDC7,ADRB2,BCAR3,OGT,ANXA7,RGS20,DDX3Y,ATP1B3,ATP2A2,ARHGEF7,NAE1,MTMR3,WASF1,USP6,ENTPD6,RCBTB2,SRSF11,NMT2,CLTC,TJP2,CNN3,CNTN1,ENTPD4,FEZ1,ARHGEF4,DCAF8,TOMM20,YTHDC1,GSDME,G3BP2,GNE,ABCC5,YAF2,SUGP2,RABEPK,VPS26C,SCML2,EFEMP1,RACK1,FDFT1,SEC24B,BAIAP2,CAP2,FOXO3,NPTN,CAMKK2,ATP2C1,ZMYND11,ERAP1,MALT1,BRD8,TCERG1,ZNF638,CBX1,HPS5,ELOVL5,KIF2A,IPO5,KTN1,LAMP2,MAP4,MARK3,MBNL1,MIA2,AFF1,PTOV1,MT3,MYO5A,CNOT4,SLC11A2,PCMT1,CDK14,SERPINE2,STRN3,PPP2R5E,PTHLH,PTPRZ1,RBBP8,RDX,CLIP1,ATXN2,TRA2B,HSPA4L,ITSN1,TROVE2,STAU1,SYPL1,MMS19,TACC1,PUM2,TP53BP1,RBFOX2,ZMYND8,FLRT2,USP1,VSNL1,XPO1,ZFAND5,UPF3A,WNK1,KAT6A" Coexpression 16288205-GeneTable2 Human Breast_Charafe-Jauffret06_1233genes GeneSigDB 6.51E-04 1.00E+00 7.23E-03 7.18E-02 159 807 "RALGAPA1,ACTN1,FMNL2,ADCY6,ADD3,PLEKHH1,KIAA1211,ESYT2,ADRB2,KIAA1324,SRPX,BIN1,PPFIA1,PKP4,BCAS1,SHTN1,SFMBT2,ARHGAP5,RGS20,ATP1A1,ATP1B3,ADGRB2,CFLAR,DST,MTMR2,CA12,CACNA1D,HIP1R,CBR1,LONRF2,LARGE1,CACNA2D2,CFL2,CHN2,MAP4K4,SLC4A8,TBPL1,ABCG1,OSBPL3,KIAA0040,CTNND2,RUBCN,GAPVD1,TCAF1,ZFYVE16,SIRPA,MYEF2,HP1BP3,SEC16A,DLG3,DMD,USP3,TRAPPC9,SIDT2,SH3GLB1,EGFR,MBNL2,F3,TBC1D16,ST3GAL6,STRADA,FDFT1,FHL1,UBE2E3,EVL,POMT1,ZMYND11,STARD10,GART,MMADHC,RND1,COPS8,GNAL,LNX1,GP1BB,GPM6B,NR3C1,TOX2,ICA1,IFI16,INPP1,DIPK1A,MAPT,MBNL1,MBP,MDM4,CCDC80,MT1M,MYCN,MYO6,NACA,NFE2L2,NUCB2,PBX1,SERPINE2,PIK3CD,KCTD15,GPSM2,PSAT1,SCHIP1,SH3KBP1,IRX1,PPP2R2C,PKN2,MAPK9,SLC26A11,SAMD9,SIDT1,ELOVL2,NKAIN1,OXR1,SLC6A15,CCDC82,KIRREL1,WLS,SGK1,FERMT1,SLC1A3,CCDC88A,SHANK2,MTERF2,SMARCC2,KDM4B,ZSWIM8,KIF1B,CLSTN2,POGZ,ITPRID2,RGL1,GSE1,NSFL1C,PRRC2C,ASTN2,CAMTA1,IQCE,TBL1X,MGRN1,EHBP1,RBFOX2,TRPS1,DCBLD1,RUSC1,TTC3,CADM1,VSNL1,NPDC1,ZNF24,ATP6V0E2,ZNF74,ZBTB38,ZBTB16,SH3GLB2,DNALI1,SLC38A1,RNF103,NAV2,SNX27,ITM2C,FRMD6" Coexpression 15459216-TableA2d Human Leukemia_Haslinger04_24genes GeneSigDB 6.52E-04 1.00E+00 7.23E-03 7.18E-02 9 18 "BCL7A,ZNF804A,EFNA2,EPB41L2,TUBB3,PNMA2,TPM2,SSBP2,TRIM16L" Coexpression 18356575-Table1b Human MesenchymalStemCells_Rider08_21genes GeneSigDB 6.52E-04 1.00E+00 7.23E-03 7.18E-02 9 18 "ADAR,APC,NUMB,BTRC,ABCG2,PARD6A,FGF1,FGFR1,GJB1" Coexpression 14675778-Table2 Human Viral_Okada03_25genes GeneSigDB 6.54E-04 1.00E+00 7.25E-03 7.20E-02 11 25 "ATP1A3,SPOCK2,ATF7,GRIN2C,KCNJ4,MAPT,CHIC1,NUMA1,PTPRN,RNH1,SATB1" Coexpression M9824 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 6.72E-04 1.00E+00 7.44E-03 7.39E-02 48 196 "GAS7,NCOA1,ZNF555,RCBTB2,KMT2C,AATK,SEC24C,ARHGAP24,JAKMIP2,SEZ6L2,LPAR6,PSMA3-AS1,TESK2,GTF2IRD2,UBE2E3,CAB39,ADAM28,CNTRL,CROCCP2,GPR45,MARK3,MEF2C,MSR1,RTL5,SFR1,SMIM11A,ING3,SNRK,ZSCAN32,PID1,REV3L,RNF220,PAQR6,CCDC112,SAFB,NSFL1C,TACC1,CYB561A3,TLR4,PIK3R5,TPD52L2,CDK20,DCBLD1,SGK3,CLIP2,TFIP11,NUP214,IFT88" Coexpression 17344918-SuppTable1 Human Leukemia_Corre07_163genes GeneSigDB 6.74E-04 1.00E+00 7.44E-03 7.39E-02 36 136 "NLGN4X,MARCH4,ALDH7A1,ADAM23,BARD1,GYG2,CH25H,NRXN3,CLCN4,CREM,DMD,SEPT9,IGF1,LAMA2,LMO2,IL17D,CD200,CLDN11,PENK,PLCL1,SLC25A23,SCHIP1,SLC22A23,VEPH1,RGS4,ATXN1,TNFRSF19,KIF21A,SLC1A3,SAMSN1,SULF2,TLR4,FAM155A,KCNT2,SCG2,RGS7BP" Coexpression 16715129-SuppTable2 Human HeadandNeck_Jarvinen06_739genes GeneSigDB 6.74E-04 1.00E+00 7.44E-03 7.39E-02 134 665 "ARID1A,GALNT16,KLRC4,ADORA2A,EP400,PPFIA1,BCAS1,CDC14B,ARHGDIA,RGS20,ATP1A2,STX16,ADAM15,BCHE,C5,CACNA1A,SLC25A14,SPAG9,NFS1,KYAT1,AIFM1,CD86,ENTPD2,CDC25B,ADGRG1,COG1,TJP2,MAP4K4,BAG4,PLCH2,DZIP3,AIF1L,SIRPA,KIAA0753,SMG7,ABCC5,APH1A,GOLGA7,TNK2,STARD3NL,PLEKHO1,EPS8,HSPA12B,BAIAP2,EFCAB2,WDR83,ATP6V1H,GAA,DBF4,GOLGB1,PRRC2B,PCLO,DIDO1,PLPP7,GRM1,AP4S1,GYG1,CELF3,IFI16,ITGAV,JAK2,KCNJ10,KCNK1,KIF5A,MEIS2,SCAMP5,P2RY13,NPTX2,NUMA1,ODF2,PBX1,PCSK2,PDYN,PFKFB2,SEMA5B,XRN1,STRN3,RC3H2,PSAT1,TNPO2,POLG,PRKAB2,APTX,PEX5,TMEM231,RALGDS,ROGDI,RBBP8,SLC25A36,ALG9,KIRREL1,YY1AP1,NEK11,RPL15,MCMBP,PAQR6,ST6GALNAC6,RXRA,SH3GL3,PPM1E,SLC15A2,SLC20A2,SLCO1A2,SPATA7,MYCBP2,SPTB,ZBTB43,NFASC,POGZ,STXBP1,KLHL7,SYT11,JMJD6,ARHGEF9,SLC37A2,TACC1,TAF6,EXOC7,TCEA1,ZNF106,LRRC8A,NPL,TRPC1,TSC1,ZKSCAN5,TBC1D15,CLDND1,CELF4,TFIP11,ZNF213,URM1,SNX27,RNF170,GAN" Coexpression 20421987-TableS2 Human Lung_Hou10_187genes GeneSigDB 6.84E-04 1.00E+00 7.55E-03 7.50E-02 37 141 "ADRB2,ASPA,ATP1A2,CA4,LDB2,JAM2,FAM189A2,FHL5,ABI3BP,DOCK4,EDNRB,EIF1,ABCA8,DLC1,FHL1,SORBS1,LYVE1,GPM6A,ADAMTS8,FAM107A,ZNF385B,KCNK3,ANLN,PTPRB,RASGRF1,VEPH1,TMEM100,GLDN,SCN4B,SCN7A,PDZD2,TACC1,SYNE1,TEK,TGFBR3,TNS1,PLEKHH2" Coexpression 17312329-SuppTable4 Human Leukemia_Juric07_106genes GeneSigDB 6.96E-04 1.00E+00 7.66E-03 7.61E-02 21 66 "ARHGEF7,KALRN,CYBB,ERBB2,BAIAP2,IQGAP2,MYCN,NCF2,PAK3,PRKCZ,RASGRF1,RIT2,MPRIP,STX1A,MCF2L,DOCK9,ARHGEF12,TIAM1,PARD3,TRIO,VAV2" Coexpression M1679 Genes up-regulated in CD-1 compared to CD-2 cluster of multiple myeloma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.96E-04 1.00E+00 7.66E-03 7.61E-02 21 66 "RAB33A,DCC,RTN3,ARMCX1,TBC1D16,MTHFD2,GPT2,TM6SF1,MIA2,RTL5,ALDH1L2,PCDH18,SLA,KIF21B,NPAS3,KLHL4,DNAJC12,VLDLR,KCNK12,PCDH20,LAMP5" Coexpression M2448 Genes upregulated in KRAS [GeneID=3845] knockdown vs control in a human cell line. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.98E-04 1.00E+00 7.68E-03 7.63E-02 25 84 "PDXK,SLC16A4,ADGRG1,GSDME,EVL,OGA,DKK3,FERMT2,ITGAV,JAK1,LAMP2,MATN2,NCF2,NPTX1,SERPINE2,SGK1,PALLD,ST5,DICER1,TNS1,TPM1,CADM1,FLRT2,WIPF1,PMEPA1" Coexpression M8186 Genes up-regulated in B lymphocytes after immunization with: monophosphoryl lipid A versus imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 7.00E-04 1.00E+00 7.69E-03 7.64E-02 43 171 "ABR,AS3MT,GRAMD1B,BCAR3,SEMA7A,ATP6V1G2,NRP2,BID,CACNA1E,FMNL3,CD86,CD38,CD81,CDC42BPB,CYBB,ARHGAP24,SRGAP3,PLXNC1,PLEKHA1,EMX2,TLR7,DLL3,LILRB4,RNFT2,HES5,MATK,PDE4D,PKD1,SH3KBP1,DRAM2,RASGEF1B,PTK2,ZDHHC14,RGS10,RPS20,ATXN1,MYCBP2,PDLIM2,TCF4,ARHGEF12,RUNDC3B,TRPM2,PLD4" Coexpression M2947 Genes up-regulated in natural T reg with non-functional FOXP3 [GeneID=50943] versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 7.00E-04 1.00E+00 7.69E-03 7.64E-02 43 171 "ARID1A,ADCY6,CARNS1,USP28,CACNA1G,NIPBL,ABCG1,IPCEF1,PLEKHM1,SNX29,EIF5,PLEKHA1,CALCRL,PAN3,LRRC23,SLC43A2,CHST15,EVL,RAPGEF6,SESN1,TDRKH,RAPGEF4,NEGR1,DISP2,LRRC4B,SESN3,TMIE,ARID4A,RGS10,AP1AR,SELL,DZIP1,RUFY2,TET1,BDP1,CEP68,CAMSAP2,TCF7,PSD3,TGFBR3,SSBP2,TTC3,JPH3" Coexpression 18722011-SuppTable2g Human Leukemia_Sanchez-Guijo08_04genes GeneSigDB 7.06E-04 1.00E+00 7.74E-03 7.69E-02 4 4 "PDE2A,RAB5B,RTN1,VAV1" Coexpression 19269367-TableS1 Mouse StemCell_vanderFlier09_134genes GeneSigDB 7.11E-04 1.00E+00 7.80E-03 7.75E-02 28 98 "ADORA1,SORCS2,SEMA7A,CACHD1,APP,LGR5,AQP4,CRLF1,PLEKHB1,LRIG1,DGKG,NRN1,PSRC1,NKD1,PIK3R1,PTPRD,PTPRO,HUNK,SCN2B,TNFRSF19,SOX6,SFPQ,SLC12A2,SLC14A1,SMARCD3,TACC1,PDLIM2,RGMB" Coexpression M441 Genes down-regulated in peripheral blood monocytes (PBMC): control versus IL-12 stimulation. MSigDB C7: Immunologic Signatures (v6.0) 7.14E-04 1.00E+00 7.82E-03 7.77E-02 32 117 "ACTN2,ADCY8,LRRC7,ANK2,GPC2,RHBDL1,FOXN3,GSDME,SLC25A18,SNX29,SEMA3D,ELN,AGAP2,ANKFY1,KBTBD12,CREG2,NEUROD2,NOS1,FAT3,PYGM,RGS7,CYB561D1,MRAP2,BAALC,GLDN,ADAL,ELMOD1,TMCC1,HECW1,PRRT1,XKR7,FRMD6" Coexpression M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.27E-04 1.00E+00 7.95E-03 7.90E-02 64 280 "ADD2,NLGN4X,SRPX,PCDH10,VAT1L,CASK,TMEM108,CA4,CA12,DIRAS1,LRRFIP1,ZNF521,ANKRD44,SIPA1L1,VCAN,BOC,EDIL3,HIPK3,FRY,PCYOX1,GABRA2,IQGAP2,GHR,COPS8,GRB10,GSN,TOX2,NEGR1,LIFR,LIMS1,MATN2,CD200,SAMD5,NAP1L3,ALDH1L2,NTRK2,NUCB1,OXTR,GNG2,PLP1,PMP22,PRRX1,PTPN13,PTX3,RASGRF2,PRR5L,RTN1,ATXN1,TNFRSF19,FAM102A,SMTN,UNC5B,MCF2L2,ST5,SULF2,PLCB1,PCDHB10,SLC44A1,TLL2,CADM1,VLDLR,ZNF711,MFF,PLSCR4" Coexpression 17099726-SuppTable1 Human Breast_HernandezVargas07_313genes GeneSigDB 7.30E-04 1.00E+00 7.98E-03 7.93E-02 56 238 "MTA3,AGT,N4BP2L1,ADGRB3,BCHE,ST3GAL5,GYG2,BTRC,MAP7,CRLF1,ABI3BP,CRYM,CSF1,VCAN,DAPK1,DCT,ELMO1,DPYSL2,ARRDC4,FIS1,EDNRB,RASGRP1,LPAR6,ELAVL2,DLC1,FOLH1,IQGAP2,GHR,HLF,HSPA1L,IRF8,IFI16,IGFBP1,KCNK2,KLRC3,MITF,PDGFRA,PIK3R1,MBOAT7,LAMA1,PXK,RASGRF1,SGK1,FBXO11,SLC6A8,SPP1,TACR1,ZFP90,PCDHA6,SLC35G2,TGFBR3,PARD3,SSBP2,VLDLR,WRN,PPP1R3F" Coexpression 12096084-Figure3-1 Human Breast_Jazaeri02_1430DownRegulated GeneSigDB 7.34E-04 1.00E+00 8.02E-03 7.96E-02 17 49 "AMPD2,NCOA1,NRP2,KALRN,ZFP28,SUGP2,GOLGA7,UFM1,SYT17,MMADHC,RPRD1A,RPS6KA2,SCN2B,MAST1,TCF4,ZNF24,PMEPA1" Coexpression 16574658-SuppTable1 Human StemCell_Udayakumar06_458genes GeneSigDB 7.39E-04 1.00E+00 8.06E-03 8.01E-02 80 366 "OSBPL8,ASPH,FUBP1,DDR1,PTBP2,SPAG9,CBS,REPS2,CDH10,ADGRG1,RCBTB2,CREM,CTH,CTNND1,RHOBTB1,NR1D2,RCAN1,DNAJB6,DYRK1A,FEM1B,FECH,AMOTL2,CAMSAP1,FHL1,OGA,ZMYND11,ERAP1,MALT1,GNAS,PRRC2B,EML4,CROCCP2,GSN,KLHL23,LIFR,MBD1,MBNL1,MEIS1,MN1,MRPL42,NF1,OGG1,PDE2A,RC3H2,PSAT1,RETREG2,EPB41L4B,POLG,MED1,PPP3CA,PPP3CB,PKN2,TUG1,SEC61A2,SH3GL2,ST6GAL1,SMTN,RAB3GAP1,TTC17,SNAP25,PALLD,KDM3A,SPTAN1,TROVE2,LARP4,DDHD2,DNMBP,CAMSAP2,DICER1,HEY1,TMPO,TPM1,TRIO,TST,HIRA,ZXDA,LRP8,GDPD5,ST7,HNRNPA3" Coexpression M8800 Genes up-regulated in Foxp3-Fusion-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background. MSigDB C7: Immunologic Signatures (v6.0) 7.49E-04 1.00E+00 8.16E-03 8.11E-02 29 103 "CSMD2,TEX22,SEMA4G,CACNB4,GPR37L1,SLC35F1,GRIN3A,RGS17,ZIC4,FOXF2,HHIPL1,CPLX1,GLDC,LUZP2,GRIA1,C1QL4,HRH3,TNFAIP8L3,KCNC2,NEFM,OLR1,ST8SIA5,PLIN1,PSD,LRFN5,SHC4,SMOC1,GPR161,ANKRD24" Coexpression M9892 Genes up-regulated in plasmacytoid dendritic cells: wildtype versus GFI1 [GeneID=2672] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.57E-04 1.00E+00 8.20E-03 8.15E-02 48 197 "ADCY6,FAM135A,ARNTL,PDE8B,MTMR9,SPAG9,ARHGAP33,LARGE1,CNGA3,FHL5,CLOCK,FEZ1,C2CD2L,CORO2B,ARPP21,WASF3,ADGRA3,GUCY1A1,ITIH2,BCO1,NELL1,SLC11A2,PAK3,ABCB1,PCDHB17P,PPP2R2B,PRKAB2,SYTL2,ATG16L1,BSDC1,MYH14,ATAT1,SATB1,SCN3A,SLC30A10,RUFY2,ZBTB43,TSPYL2,RBM26,ST5,STX1A,POPDC3,TRIM2,OBSL1,RBFOX2,TRH,PLPPR2,ZBTB16" Coexpression M7706 Genes up-regulated in CD4 [GeneID=920] T cells: control versus Ro 41-5253 [PubChem=5312120]. MSigDB C7: Immunologic Signatures (v6.0) 7.57E-04 1.00E+00 8.20E-03 8.15E-02 48 197 "ADORA3,AP2A2,ST3GAL5,CAMK2A,PRC1,TMEM184B,COL9A3,GAL3ST1,AHCTF1,MYRIP,CDC42BPB,NCOR2,C2CD2L,CEP170,FOXO3,SYT17,TPPP,RAPGEF1,PACSIN2,HMGCR,HNRNPK,KCNA4,KCNB1,KLC1,LMO2,AFF1,MYCN,GPSM2,MTRF1L,GAL3ST4,KCTD17,TTLL7,ZFHX4,SCN3A,SLC1A2,SCMH1,KIF21B,COLGALT2,SYN2,ROBO3,PDLIM2,TCF7,TK2,BEX4,METTL3,UBC,SPHK2,GJC2" Coexpression M7397 Genes up-regulated in the neuron cell line: immature versus mature. MSigDB C7: Immunologic Signatures (v6.0) 7.57E-04 1.00E+00 8.20E-03 8.15E-02 48 197 "ADD3,TXNDC16,APBA2,ARNTL,CAPRIN2,ATM,ST3GAL5,IFFO1,ENTPD4,IPCEF1,RIPOR2,SPOCK2,RABGAP1L,USP3,NR1D2,RASGRP1,PAN3,FOXO3,ACSS1,GOLGB1,PRRC2B,GSN,MBP,LYRM9,ZNF862,NF1,PIK3R1,POU6F1,PPP3CA,KANSL1,VPS13C,SYTL2,ZSCAN2,GAL3ST4,ATXN7,RASA3,FAM102A,YPEL4,POGZ,SYNE2,VAMP1,PIK3R5,TSC1,MICAL1,RNF103,MPPE1,MARCH8,SENP7" Coexpression M4405 Genes up-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.57E-04 1.00E+00 8.20E-03 8.15E-02 48 197 "ABCF1,KLRC4,ADRB2,SPOP,FAM135A,AQP6,ATM,EIF4G3,BTK,CACNA2D2,PPT2,CX3CR1,IP6K1,DBT,KIAA0753,SIDT2,ATP8A1,POLR1B,SEMA6C,CSDC2,ADAP1,KLRC3,MATK,P2RY13,NEK1,NELL2,NRCAM,NUCB2,LRRN3,PRKAR1B,SYTL2,SIDT1,PTCH1,PTPRO,GTDC1,SUGCT,SCN2B,SH3BP2,CHD9,WDR37,SLC14A1,SPATA7,GSE1,TCF7,TCF7L2,TLL2,MAP3K12,CIAPIN1" Coexpression M7238 Genes up-regulated in cortical thymocytes versus thymus whole cortex. MSigDB C7: Immunologic Signatures (v6.0) 7.57E-04 1.00E+00 8.20E-03 8.15E-02 48 197 "ACHE,SLC12A5,FZD9,ATP2B3,GYG2,RUNX1T1,KCNAB3,CNTN1,AATK,FEZ1,ARHGEF10,ATRNL1,ECE2,DPP6,ERBB2,CAP2,RASL10A,B4GALNT1,ARPP21,HIGD1B,ALDH1L1,GDF9,GNG4,GPR37,PTPRT,KCNJ3,KCNJ9,KCNQ2,PACRG,MPP2,MYO6,NEUROD2,PPP2R2B,ZDHHC14,NEK11,TCP11L1,SCN2A,SYBU,SLC4A3,SORCS3,KIF21B,COBL,TRIM2,OBSL1,TNR,TRH,FLRT1,PCBP4" Coexpression 15155529-tableS2b Mouse StemCell_Brunelli04_15genes GeneSigDB 7.58E-04 1.00E+00 8.20E-03 8.15E-02 6 9 "DLX1,FOXM1,GFER,KCNK2,ATF7IP,SPP1" Coexpression 15695585-Table3 Mouse StemCell_Zhao05_10genes GeneSigDB 7.58E-04 1.00E+00 8.20E-03 8.15E-02 6 9 "BIN1,SULT4A1,CNN3,PTPRO,SATB1,SELL" Coexpression M2530 Genes down-regulated in A375 and 397 cells (melanoma) by forced expression of PLZF [GeneID=7704] off adenovirus vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.58E-04 1.00E+00 8.20E-03 8.15E-02 6 9 "ARHGDIG,CALB1,RGS6,CACNG7,TMEM107,PBX1" Coexpression 15860227-Table1b Human Immune_Inomata04_15genes_down GeneSigDB 7.61E-04 1.00E+00 8.22E-03 8.16E-02 8 15 "CDC42BPA,GAS7,DDO,MYRIP,SEC14L1,ASRGL1,FAIM2,DICER1" Coexpression M9251 Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion and up-regulated in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.61E-04 1.00E+00 8.22E-03 8.16E-02 8 15 "TAOK1,PCLO,LIMS1,NCAM1,NPY,KAZN,TCF12,VGF" Coexpression 15940248-Table2 Human Uterine_Vanharanta05_54genes GeneSigDB 7.67E-04 1.00E+00 8.26E-03 8.20E-02 16 45 "PDE8B,ZFYVE9,COL9A2,CRMP1,HEPH,EDNRA,GPM6B,MEST,PLP1,PRKCB,SATB2,ZMAT3,TRPS1,NAV2,ITM2C,HRASLS" Coexpression M13714 Down-regulated genes displaying alternative splicing in MDA-MB-435 cells (breast cancer) whose metastatic potential has been reduced by expression of NME1 [GeneID=4830]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.67E-04 1.00E+00 8.26E-03 8.20E-02 16 45 "CLK4,API5,NAE1,COL9A3,TSPAN5,EIF4G2,TTBK1,ADAMTS13,MAPT,PDCD2,PTK2,SPP1,FCHO1,PCDHAC2,PCDHA5,SEMA3B" Coexpression M18274 Genes up-regulated in uterine fibroids vs normal myometrium samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.67E-04 1.00E+00 8.26E-03 8.20E-02 16 45 "PDE8B,ZFYVE9,COL9A2,CRMP1,HEPH,EDNRA,GPM6B,MEST,PLP1,PRKCB,SATB2,ZMAT3,TRPS1,NAV2,ITM2C,HRASLS" Coexpression M2577 "Top 50 marker genes for anaplastic oligodendroglioma (AO), a class of high grade glioma." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.67E-04 1.00E+00 8.26E-03 8.20E-02 16 45 "ASIC1,API5,PDE8B,HIP1R,CRY2,ELMO1,TNK2,OLIG2,APC2,GRIK2,KCNK3,NCAM1,POLR2F,RPS20,ABCC8,FLRT1" Coexpression 16135788-Table13 Human Breast_Wang05_410genes_up_BT-BAF57cells GeneSigDB 7.69E-04 1.00E+00 8.27E-03 8.22E-02 62 270 "ADD2,NLGN4X,SRPX,PCDH10,VAT1L,CASK,TMEM108,CA4,CA12,DIRAS1,LRRFIP1,ZNF521,SIPA1L1,VCAN,BOC,EDIL3,HIPK3,FRY,PCYOX1,GABRA2,IQGAP2,GHR,COPS8,GRB10,GSN,TOX2,NEGR1,LIFR,MATN2,CD200,SAMD5,NAP1L3,ALDH1L2,NTRK2,NUCB1,OXTR,GNG2,PLP1,PMP22,PRRX1,PTPN13,PTX3,RASGRF2,PRR5L,RTN1,ATXN1,TNFRSF19,FAM102A,SMTN,UNC5B,MCF2L2,ST5,SULF2,PLCB1,PCDHB10,SLC44A1,TLL2,CADM1,VLDLR,ZNF711,MFF,PLSCR4" Coexpression 19036130-TableS1a Mouse Viral_Mendoza-Villanueva08_1830genes GeneSigDB 7.76E-04 1.00E+00 8.33E-03 8.28E-02 287 1561 "ABCF1,ACADM,AS3MT,NDRG2,GALNT16,ADD3,KLHL13,SRPX,ABCD2,BBOX1,BIN1,ANK1,PI16,APBB2,GPAM,CACHD1,AQP4,ARRB1,ASPA,ASPH,NUMB,RASL11B,DYNLL1,ATP1A1,ATP1A2,ALDH7A1,MYOM1,MPDZ,CFLAR,BMP7,DST,C1QC,SGCE,CACNG1,CAPN3,CAST,CARS,RUNX1T1,PRC1,LDB2,CD86,CD38,ENTPD2,CD81,MYOM2,CDH2,LRRFIP1,LARGE1,CDO1,CFL2,JAM2,SLIT2,LHX2,RAB28,CLU,TJP2,ABCG2,LY86,CNN3,ABI3BP,CP,CLOCK,AKAP12,GDA,CRYM,CSF1,CSF1R,FEZ2,FEZ1,PDE4DIP,CST3,CTH,CYBB,DAPK1,ARMCX4,ARMCX2,DCT,G3BP2,CHRDL1,DLX1,DNM1,NR1D2,DOCK2,DTNA,ABCC9,EBF1,EEF1A2,FEM1B,HEYL,EFNA3,EIF5,PCOLCE2,ELN,CALCRL,IGSF6,EXTL2,ARMCX1,ACSL4,TUBB3,TAOK3,EFEMP1,ST3GAL6,FCGRT,OLFM1,FGF13,FGFR3,FHL1,SCARA3,CAP2,FOXM1,FLNC,FOLR2,SORBS1,SMC2,USP16,PDLIM5,FYB1,CHL1,STARD10,MYOZ2,GATM,TUBA8,CSDC2,GHR,DBF4,GLUL,HTATSF1,GNAS,GNG4,GPT2,PSRC1,ADGRA3,GP1BB,GPD1,GPM6B,GPR34,GPR37,GRB10,PLPP7,NR3C1,GSN,COQ10A,GSTT2,SOX21,GUCY1B1,WIF1,NCKAP1L,ACOT7,HNMT,HSP90AA1,IDH3A,MYLK2,IGF1,IL6ST,JAK1,KIT,LAMA2,STMN1,LIFR,LMO2,LSS,ASPRV1,GPR155,MARK1,MBNL1,MBP,TM6SF1,MEF2C,AFF1,CCDC80,TAGLN3,MX1,MYCN,FXYD6,NASP,NCAM1,NFIX,NNAT,NPY,NOVA1,NPR2,NTRK2,DDR2,NUCB2,ETFRF1,PDE2A,PDE4B,PDGFRA,ENPP2,PFKFB3,PGAM2,PHKG1,SERPINE2,ANLN,PIK3R1,SNX10,ZFYVE21,TMEM38A,GPSM2,SMOX,FXYD1,PMP22,SCHIP1,PRRX1,FA2H,PPP1R1A,PPP3CA,PKIA,RELN,SYTL2,GDPD2,PSMD13,PTCH1,PTHLH,PTPN13,PTPRO,PYGM,RAB3IL1,RBBP6,ZDHHC14,ZYG11B,RGS10,SLC25A36,RNASEL,ZFHX4,MYH14,ROBO1,TMEM100,HUNK,RYR1,MAPK12,SATB1,RASA3,SH3BGR,CPEB3,SHMT2,FHOD3,PEX26,DHX30,LIMS2,SLC11A1,SLC12A2,SLC15A2,SLC22A4,SLN,SMARCD3,SPP1,ERC1,UNC5B,THSD1,ELOVL4,ADHFE1,PHLDB1,ACSBG1,POPDC3,DDHD2,AGTPBP1,TBX15,ACSL6,TCF4,TCF7,SYNE1,TEK,ZFPM2,ZNF106,TIMP4,TLR4,TPM1,TPM2,SYNPO2,DCBLD1,RFTN2,TUBB2A,TMEFF2,SGK3,UBE2H,AMOT,SLAIN1,VLDLR,WIPF1,P2RY12,ZIC1,NDRG4,SEMA3B,PLD4,VANGL2,SSPN" Coexpression 18081427-TableS8 Mouse Breast_Crawford07_981genes GeneSigDB 7.78E-04 1.00E+00 8.35E-03 8.29E-02 135 673 "ACADM,ACTN1,FMNL2,RNF157,ADD3,MTA3,TXNDC16,C1QTNF1,ANK3,CASK,ZBTB10,ALDH7A1,DOCK11,MPDZ,BCL7A,GPR146,BMP7,ST3GAL5,SCAPER,DDR1,NFS1,ARHGEF25,AP4M1,LARGE1,MAGI1,CCPG1,FOXN3,B4GALT6,LHX2,ARHGEF6,CNR1,FAM149A,COL4A5,CRY2,CTNND1,DCAF8,AIF1L,RABGAP1L,DLX1,DMD,CD99L2,NR1D2,CDON,WDPCP,ATL1,FRY,OPTN,SLC43A2,SPEG,RTN3,TBC1D16,FHL1,PCYOX1,EVL,NBEA,USP21,ST6GALNAC3,STAU2,ERAP1,INPP5K,STARD10,GHR,GLRB,GLUL,KIF3A,PADI2,MAN1B1,BACH2,SYNPO,IDH3B,USP54,JAK1,KCNH1,GATD1,LAMP2,ARHGAP12,MEF2C,SAMD5,SESN3,MTTP,MYO6,NME4,ETFRF1,PDE4B,PDE4D,SERPINE2,PMP22,EXOSC10,RETREG2,SEPT4,TATDN3,PPP2R5C,CNNM2,SLC22A23,ANKHD1,PTPRG,SLC25A48,RALGDS,CCDC82,MAPK12,ATXN1,CLSTN1,SLC6A9,SLC15A2,SMARCC2,RCOR3,IFT122,SNRPN,PDZRN3,KIF21B,GLT8D1,IQSEC2,ST5,ADHFE1,SULF2,PLCB1,EXOC7,TBL1X,AZIN2,PSD3,ATP13A2,TGFBR3,LRRC8A,TNFRSF1B,TNS1,TPM2,RGMB,NR2C2,CADM1,UBE2H,VLDLR,AGMO,LMAN2L,ADAMTS9,FBXO36" Coexpression 18977325-Figure5f Human Leukemia_Krivtsov08_36genes GeneSigDB 7.80E-04 1.00E+00 8.35E-03 8.29E-02 13 33 "ALAD,ARHGEF1,CD38,ABCG1,PPP1R16B,HDAC9,SLC12A6,RASGRP1,GPSM2,OXR1,GSTCD,IFT122,SP4" Coexpression M13859 Genes up-regulated in hairy cell leukemia (HCL) compared with normal and other neoplastic B cell populations. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.80E-04 1.00E+00 8.35E-03 8.29E-02 24 80 "GAS7,ARRB2,DST,RCBTB2,SUSD5,PDE4DIP,SLITRK5,SDC3,DAPK1,PLXNC1,EPB41L2,DLC1,FGFR1,HPGDS,GABARAPL2,NOVA1,PCDH9,MAPK10,SYT1,TACC1,CAMTA1,TCF7L2,TRIM2,TIMP4" Coexpression 16273092-TableS1e Human InVitro_Bild06_98genes GeneSigDB 7.80E-04 1.00E+00 8.35E-03 8.29E-02 24 80 "AXIN2,LRBA,QKI,VCAN,YTHDC1,ABI2,PLEKHA1,NR3C1,NEK1,NRDC,PIK3C2A,MAPKAP1,PTHLH,ZNF532,FERMT1,CHD9,FBXO11,TMCC1,KDM4B,ANKRD12,KAZN,WASHC4,FRYL,ZMAT3" Coexpression M2000 Genes with high-CpG-density promoters (HCP) bearing histone H3 K27 trimethylation mark (H327me3) in embryonic stem cells (ES). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.90E-04 1.00E+00 8.43E-03 8.38E-02 15 41 "CACNA1E,DCC,ZNF804A,NTM,KCND3,KCNIP1,ARX,SLITRK3,TAL1,PCDHB15,PCDHB7,PCDHA3,PCDHA2,PRDM8,NETO1" Coexpression 16044152-SuppTable3 Human Breast_Gyoerffy05_70genes GeneSigDB 7.90E-04 1.00E+00 8.43E-03 8.38E-02 15 41 "DOCK2,ELAVL4,EPB41L2,SDCBP2,PTPN5,RASSF8,ELOVL5,LAMA2,IRX1,SYTL2,CASC3,SMARCE1,POPDC3,UNC5D,PPP1R3F" Coexpression M6718 Genes up-regulated in endothelial cells: IFNG [GeneID=3459] versus IFNG [GeneID=3459] and B. burgdoferi. MSigDB C7: Immunologic Signatures (v6.0) 7.90E-04 1.00E+00 8.43E-03 8.38E-02 44 177 "SNX30,BIN1,PDXK,CAPRIN2,EIF4G3,ATP6V0A1,CD81,CCPG1,SOCS6,PLEKHM1,HP1BP3,SNX29,FRY,PLEKHO1,EZH1,PCYOX1,NEK6,ACSS1,SESN1,GLUL,GSN,GYG1,IRF8,IL6ST,KCNJ10,KHK,TTYH2,MBP,ADAM22,PRKACB,RAB3A,RAB3IL1,RAD51D,ZDHHC14,RGS10,KIF21B,ZC4H2,TPCN2,ATP13A2,TIAM1,TLR4,NR2C2,ADAMTS10,AAAS" Coexpression M1676 Genes whose expression negatively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.94E-04 1.00E+00 8.45E-03 8.40E-02 78 356 "DPF1,ADD2,AQP6,PRX,ARSF,KSR1,BMP7,CDK5R1,CA12,CALB2,KALRN,CAMK2A,CAMK2B,CCNT1,CDH18,SLC24A2,DGCR9,COL11A2,DCT,DNM1,DNM2,DSCAM,USH1C,EDIL3,EFNB3,LINC00599,REEP2,FABP7,CACNG3,FGF1,DPYSL4,GABRA1,GABRG2,RUNDC3A,CRCP,GPR75,DCLK2,LILRA1,GPR12,AP4S1,SOX21,TLX1,KCNJ4,KCNJ10,MYT1,NHLH1,NNAT,NPPA,KCNK10,PDPK1,CAMKV,SEPT4,PTN,RAB3IL1,RGR,KLHDC8A,MEG3,SCN2A,ASIC4,BCAN,SLC1A2,SLC1A7,PREX2,SOX2,SOX10,SPTB,DDN,ATP10B,INKA2,TACC1,CNTN2,PHF24,TEX15,TF,LILRA4,OSBP2,FLRT1,NLRP3" Coexpression M6760 Genes up-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.95E-04 1.00E+00 8.45E-03 8.40E-02 38 147 "BCAR3,MARCH4,APOC2,USP2,ZFYVE9,MYL6B,ABCG2,LY86,CP,DOCK4,MFAP3L,EDNRA,IGSF6,TACC2,DKK3,PRUNE2,ATG4C,NOVA1,DDR2,OPHN1,P2RX7,SH3KBP1,PTN,ZMAT4,MTERF2,TNIK,PEG10,DBNDD2,ANO4,TPCN2,LRRC8A,TNNT1,CADM1,CLEC2L,BEST1,TMEM198,MARCH8,PHTF2" Coexpression M6338 Genes down-regulated in Vd2 gamma delta T cells: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 7.95E-04 1.00E+00 8.45E-03 8.40E-02 38 147 "ANK3,APAF1,ARNTL,ATP2B1,CDH10,CHRM4,OSBPL3,ATRNL1,RIMS3,NR1D2,DPP6,FRY,EPS8,DUSP27,EXTL1,DPYSL4,STARD10,SLC2A6,ATCAY,JAK1,KLRC2,L1CAM,MYT1,FXYD6,CASTOR1,PLEKHB2,WLS,ITSN1,CPEB3,SLC6A8,SMOC1,SYPL1,OBSL1,NAV2,TMEM163,SLC17A6,TMEM63C,JPH3" Coexpression M8905 Genes up-regulated in CD4 [GeneID=920] T cells versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 7.95E-04 1.00E+00 8.45E-03 8.40E-02 38 147 "DSCAML1,LRFN2,OSBPL6,CNTNAP1,RGS9,FUBP1,CANX,INA,SLC16A4,CDC42BPB,SLC45A1,E2F6,FSD1L,EBI3,KCTD3,GALR1,NEK6,B4GALNT4,TOX2,SCIN,TTYH2,CHIC1,STK32C,NHLH1,PLCD1,EPDR1,PTPN13,ROBO1,CCDC112,SEMA6D,SCP2,SMARCE1,WDTC1,RBFOX2,RGMB,TRIM9,NAV2,PLSCR4" Coexpression M1751 Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated only in mature (peripheral blood) regulatory CD4+ [GeneID=920] T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.96E-04 1.00E+00 8.45E-03 8.40E-02 14 37 "RCBTB2,NIPBL,ANKRD44,LPAR6,PTK2B,RAPGEF6,BACH2,DIPK1A,JAK1,SATB1,ST8SIA1,SYNE2,WIPF1,WNK1" Coexpression M8129 Genes down-regulated in AGS cells (gastric adenocarcinoma): control versus H. pylori LPS. MSigDB C7: Immunologic Signatures (v6.0) 8.01E-04 1.00E+00 8.50E-03 8.45E-02 41 162 "CLK4,MTA3,OGT,SEMA7A,CCNT1,CDK11B,NIPBL,ENTPD4,RBM39,ING4,MALT1,TNRC6A,LILRB4,EML4,CNTRL,JAK1,KTN1,VWA5A,MBNL1,SESN3,MX1,PDE2A,PDE4D,PIK3C2A,PLCB2,TUG1,TRIM68,ZC3H14,ATXN7,DOCK10,PPP4R3A,ZKSCAN3,USP33,BDP1,MYCBP2,ERBIN,MAPK8IP3,DOCK9,ARHGAP9,DICER1,RUNDC3B" Coexpression M1281 Cluster PAM5: genes changed exclusively in hepatocellular carcinoma (HCC) samples from 27 month old mice deficient for TXNIP [GeneID=10628]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.02E-04 1.00E+00 8.51E-03 8.45E-02 27 94 "SORCS2,MARK4,CCKBR,CLGN,CHN1,CABP1,SPOCK3,ELAVL4,CIT,ZBTB45,SOWAHA,KCND3,KCNJ4,MITF,MYH7,NCAM1,RAB3IL1,ITSN1,SP4,ELOVL4,FGD4,HHIP,TLR4,CHST5,AMOT,SMARCAD1,FZD3" Coexpression M8803 Genes up-regulated in Foxp3-ires-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background. MSigDB C7: Immunologic Signatures (v6.0) 8.11E-04 1.00E+00 8.59E-03 8.54E-02 31 113 "PWWP2A,CACNA1A,NGB,CDH18,CHRM1,CHRNA4,LRRC3B,RIMS2,SNPH,OLIG1,SNX29,EEF1A2,GALR1,GCK,MYH7,NPPA,SETD4,IGSF11,PDCD2,POU3F2,HYDIN,MAPK12,SCN2B,FERMT1,MYH15,ENKUR,TMEM121,RIMBP2,ZFP41,PROCA1,CPNE4" Coexpression 20460173-ImmPortCD40LandAnti-IgMvsControl Human Immune_Kong10_2491genes_ImmPort_CD40LandAnti-IgMvsControl GeneSigDB 8.13E-04 1.00E+00 8.60E-03 8.54E-02 291 1586 "ABAT,ABR,ACLY,KDM5D,ARID1A,ADD1,ADD3,ADORA2A,AP1B1,MTUS1,BCAR3,MRTFA,AMH,ANK3,SEMA7A,PKP4,APBB2,GAS7,APOC2,CASK,RGS20,ASPH,CHRD,ATM,ATP2B1,NOL4,ATP6V0A1,BACH1,BARD1,BCL7A,BCS1L,BLM,CFLAR,BMP7,ARHGEF7,BTK,SGCE,OSGIN2,CACNB4,CALM1,CAST,RUNX1T1,CBS,CD86,SCARB1,CD38,CD81,LRBA,ARHGEF2,CDC25B,CDH2,UBE2L6,COPB2,ADGRG1,CLCN4,CLU,MYL6B,STOML1,SULT4A1,LY86,ARHGEF6,CNR1,LETMD1,MAGED1,IFFO1,COX4I1,CLOCK,CRY2,RNF14,ABCG1,CS,LRIG1,FEZ2,PDE4DIP,CST3,SLITRK5,KIAA0040,HDAC9,DCAF8,TOX,TBC1D5,RIMS3,PHYHIP,TOMM20,SCRN1,IP6K1,GIT2,ARMCX2,ZNF804A,ELMO1,B3GAT3,GSDME,SV2B,SRGAP3,G3BP2,RABGAP1L,DNM1,DMPK,DOCK2,DPYSL2,GNE,DNAJB6,DYRK1A,ABCC5,E2F5,TSPAN5,EDN3,PHC2,RBM12,CELSR3,SUGP2,EGR3,EIF4G2,EMX2,EPB41L1,EPB41L2,LRRC17,RASGRP2,ERCC2,DENND4A,RRAGB,SH3YL1,PTK2B,TUBB3,RACK1,FKTN,FGR,AMOTL2,ATP5PD,UBE2E3,AGAP2,FOXM1,PDLIM5,TRIM16,RASL10A,KHDRBS3,CSPG5,STAU2,FYN,STAG2,IQGAP2,GAP43,SEPT9,WASF3,GLS,GNAS,GNG4,FERMT2,LILRB4,GPD2,LILRA2,GPER1,NUDT21,GRIK2,GRIN2C,CIT,PSIP1,RNFT2,HAS2,PACSIN2,NCKAP1L,ATXN2L,ACOT7,GABARAPL2,IDH3A,IDH3B,INPP5B,TUBB2B,ITGAV,ITPKB,JAK1,JAK2,KCNN3,KHK,KIF2A,KLC1,STMN1,SMAD1,MAT2A,MEIS2,MIA2,CD200,MSR1,PTOV1,MT3,MTR,NASP,NEFM,CNOT4,NUCB1,SETD4,OCRL,OGG1,PDE2A,PENK,CDK14,ABCB1,PKM,GPSM2,PLEC,SMOX,PMS2,POLR2F,PPP2R5C,PRKACB,PKIA,MAPK8,MAPK9,MAPK10,PRPSAP2,CNNM2,NDUFS7,PTAFR,PEX5,QDPR,RBBP8,RDX,RGS3,SBF1,ATXN2,SCP2,SEC14L1,SGK1,MYO18A,FNDC3A,ST6GAL1,CCDC92,CLSTN1,ABLIM3,SLC2A5,SLC12A2,SMARCA4,SNRPN,USP33,WDTC1,DOK5,SPTAN1,DDN,LMO3,TAB2,POGZ,STXBP1,AJAP1,GSE1,NSFL1C,DNAJC9,PLCB1,SYP,SYPL1,MMS19,KAZN,TAF6,KIAA0930,CUX2,TCF7L2,SYNE1,DOCK9,ITGB3BP,TIAM1,R3HDM1,CABIN1,TP53BP2,RBFOX2,LILRA4,TPM3,TPM4,ZNF384,ZMYND8,RUSC1,TSN,SSBP2,TTC3,ZKSCAN5,TUBB2A,HEPACAM,UCHL1,GORASP1,VAV1,NSD2,CLDND1,XPO1,SF1,ZBTB14,ZNF23,ATP6V0E2,PRDM2,LRP8,EVI5,MPPE1,PHTF2,ZNF248" Coexpression 15466185-Table4 Human StemCell_Upender04_17genes GeneSigDB 8.21E-04 1.00E+00 8.68E-03 8.63E-02 7 12 "CCK,NECTIN3,CLDN11,SERPINI1,PTPRG,CLSTN2,ADAMTS9" Coexpression 17724462-TableS1 Human StemCell_Nuytten08_1622genes GeneSigDB 8.23E-04 1.00E+00 8.69E-03 8.63E-02 260 1402 "SERPINA3,ASIC1,ARID1A,SLC12A5,PCDH19,WDR35,MARCH4,OGT,PPFIA1,DGKD,API5,USP37,PDXK,ASPH,NCOA1,NUMB,SLC4A4,ATP2A2,MTMR9,AZGP1,FUBP1,C5,BAIAP3,DDR1,CALB1,CAST,SLC16A4,SCARB1,ENTPD6,REPS2,ZBED1,CDC42,ADGRG1,FOXN3,B4GALT6,ARHGAP22,LHX2,RAB28,PPT2,NMT2,NGEF,FBXO7,TJP2,ABCG2,QKI,MAP4K4,CNN3,IQCK,SLC25A27,MAGED1,TBPL1,COX4I1,NECTIN3,CPS1,CLOCK,CREM,ENTPD4,ABCG1,OSBPL3,PHACTR3,DZIP3,FAM131B,KIAA0408,KIAA0513,KCTD8,DGKG,TOMM20,SCRN1,SPOCK2,SIRPA,DNAJC6,CEP170,G3BP2,RABGAP1L,DLG2,NR1D2,DMTF1,SLC12A6,DPYSL2,TOM1,ABCC9,TSPAN5,PHC2,ANKRD46,TMTC1,RBM12,YAF2,APH1A,EGFR,MBNL2,EIF4G2,SORBS3,STARD3NL,ENO2,VPS13B,SPEG,KATNAL1,TUBB4A,EFEMP1,DLC1,ST3GAL6,FER,FGF1,OLFM1,FGF13,ACTL6B,FHL1,SYNCRIP,FOXM1,TMEM107,PDLIM5,FAM49B,STAMBP,USP21,PRELID3A,CGREF1,DENND2A,GAD1,GBX2,ARFIP1,SESN1,MALT1,GK,GLRB,GLS,KIAA1958,GNAS,NUDT21,GRB10,RAPGEF1,ADAMTS13,SOX21,ADAMTS6,HAS2,HBA1,PACSIN2,HMGCR,HP,IFI16,RBPJ,IL6R,IL6ST,ITPKA,KCNK1,GATD1,KHK,KIF2A,KTN1,TTYH2,LAMP2,LIFR,LIMS1,ARHGAP12,MATN2,MEST,KITLG,NRBP2,MX1,MXI1,NAP1L2,NFIA,NPTX1,OGG1,PAH,PBX1,ETFRF1,PDE4A,BEST3,SERPINI1,ANLN,PKD1,XRN1,PCDH18,EPB41L4B,CRLS1,PPP3CC,CEP41,PRKCZ,GDPD1,SAMD9,PTN,OCIAD1,PTPRZ1,PLEKHB2,RAP1GDS1,ENOX1,ZYG11B,RGS4,RGS10,RNASEL,EXD2,ROBO1,SPIN3,RIMKLA,RYR3,SAFB,SEC14L1,GALNT10,SH3BGR,SH3GL2,ST6GAL1,SLC1A3,SLC6A8,SLC12A2,BTBD7,OGDHL,SNCA,KIF13A,TMCC1,PDZRN3,TRERF1,NMNAT2,ERC1,BEX1,DBNDD2,RBM26,ZNF302,THSD1,SSTR1,SYNE2,ARHGEF9,NUDT10,SYN1,TACC1,TBL1X,TCF4,TCF7L2,ZEB1,TCF12,PUM2,DICER1,TMEM121,ZNF106,SLC44A1,TIAM1,TJP1,LRRC8A,TMPO,TPD52L2,TSC1,TUBB1,VAV2,WIPF1,NSD2,XRCC4,PCDH20,FMN2,LYPD6,DPYSL5,ANKS1B,DHX33,PRTFDC1,GOPC,RTN4,NLRP3,SSPN,RNF146,ST8SIA2,ZNF30,CPNE4" Coexpression 18410693-TableS12 Human Leukemia_Kiiveri08_100genes_MLLParallel GeneSigDB 8.26E-04 1.00E+00 8.72E-03 8.66E-02 19 58 "AK2,VAT1L,FEZ2,MATR3,CPEB2,SIDT2,PLXNC1,PAN3,SH3YL1,GPM6B,LILRA1,SMAD1,PIK3AP1,MBNL1,MEIS1,MTMR10,SYNE2,TCF4,PCDHGC5" Coexpression 17192395-TableS2b Human StemCell_Macaulay07_516genes GeneSigDB 8.40E-04 1.00E+00 8.85E-03 8.80E-02 101 483 "ACTN1,AMPD2,APBA2,DGKD,ARHGDIA,ARNTL,ARRB1,BID,AP1M1,CAMK2G,ADGRG1,RCBTB2,RAB33A,CLU,DNAJB5,MAGED1,TCEAL2,PNKD,RIPOR2,KIAA0513,GIT2,G3BP2,CD99L2,ABI1,DNM1L,AASS,STARD3NL,HSD17B14,PLEKHO1,ARMCX1,ATP8A1,ST3GAL6,MED12L,SEMA6C,EVL,FYB1,FYN,NEK6,NFU1,LOXL3,GPD2,GSN,NCKAP1L,ITPKA,ITPKB,JAK1,KIF2A,LIMS1,LSS,MATK,MEF2C,MEIS1,MEST,GIT1,NDUFA5,NINJ2,OGG1,PFKP,SERPINE2,PLCB2,SEPT4,PRKACB,PTAFR,RGS3,ROBO2,TMEM206,PRR5L,KCNIP2,MAPK12,SLA,ELMO2,SLC20A2,SNCA,SNRPN,SPTB,ZC4H2,SYT11,MLC1,SYPL1,TACC1,ROBO3,OBSL1,ARHGAP9,ATP13A2,SLC44A1,PIK3R5,TPM2,TPM4,TRO,TUBB1,VAV1,MICAL1,CLIP2,LAT2,NPDC1,PCDH20,ZBTB16,PRTFDC1,NT5M,RTN4,ST8SIA2" Coexpression M5152 Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (5 worms/well). MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "RBM10,FAM131A,ASTN1,BLM,CACNA1E,CALB2,RUNX1T1,CD38,CDC42,AKAP6,MYRIP,PLCH2,MYEF2,SV2A,CHST15,TESK2,BAIAP2,MYOZ2,RUNDC3A,CBX1,FERMT2,LILRA2,AP4S1,RASSF8,IDH3B,RBPJ,KLHL23,KTN1,MKLN1,MMP16,NCAM2,NFIA,PDE2A,PDYN,MAPK9,RNASE1,SORCS3,MAPKBP1,KDM4B,ZCCHC24,ZSWIM8,PEG10,ZC3H4,TAF6,DNAH7,ZNF177,FAM13C,HNRNPA3" Coexpression M5424 Genes up-regulated in comparison of eosinophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "ARRB1,CACNA1G,CALM1,LRRFIP1,DLGAP1,CLOCK,CLIP3,PLCH2,PITPNM3,TBC1D5,MAML1,GIT2,DBT,PLXNC1,EIF1,CHST15,GCNT2,USP19,GRB10,SOX21,PACSIN2,ELOVL5,HSPA1L,HTR2A,IGFBP1,INPP5B,KIT,LAMP2,SHC3,MID1,NFE2L2,OMG,PTAFR,ZSCAN32,PTPRE,SMPD3,CPEB3,WDR37,MAST1,SYNE2,SYT1,CAMTA1,PCDHGA10,ZNF34,TUB,UGT8,ZFAND5,NAV3" Coexpression M6731 Genes down-regulated in spleen dendritic cells from healthy mice: 33D1+ versus DEC205+ subpopulations. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "TBC1D14,ALCAM,DPY19L3,GPR146,PROM1,SYNJ2,LDLRAD4,CA8,CABP7,AIFM1,ZBED1,CHN2,RAB33A,CLCN4,ABCG2,KIF26A,CHRDL1,ARRDC4,EXTL2,MAD2L2,ERGIC3,GAD1,NEK6,WASF3,RAB30,GPD2,ADAP1,STON1,RNFT2,PACSIN2,HMGCL,INPP1,TUBB2B,KIT,PDE4A,SSH1,PTCH1,RGS10,SARS,FAM102A,SLC22A4,INTS9,EPB41L3,RGL1,ATP11A,TACC1,SEMA4A,TUBB2A" Coexpression M9236 Genes down-regulated in CD8 T cells with STAT4 [GeneID=6775]: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "TNRC6C,TMEM263,EIF4G3,ATP6V0A1,JAZF1,CLCN4,ZFP28,CDC42BPB,SIPA1L1,FAM169A,PUM1,ARHGAP32,BLOC1S6,PLEKHA1,NBEA,SARAF,SYT17,SESN1,NR3C1,BACH2,IRF8,MEF2C,CD200,BLOC1S2,MYO9A,NFYA,ABCB1,VPS13C,PTK2,BEND5,BSDC1,TMLHE,PCMTD2,SATB1,CNKSR2,SLC12A2,COA1,ZHX3,KDM4C,TAC3,FRYL,TMPO,TRPC1,ZNF711,ZNF154,SLC30A4,HPS4,NETO1" Coexpression M7921 Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "KLHL13,OGT,CASK,ARHGAP5,WASF1,FOXK1,LRRFIP1,CHM,B4GALT6,PLCH2,DZIP3,FGFR1OP2,SV2A,EIF4G2,CDHR1,WAC,SH3YL1,ATP2C1,CELF1,ZMAT1,STAG2,GAB1,NR3C1,ZNF496,PSIP1,GUCY1A1,NELL2,PCDH9,TMEM38A,CEP97,ZMAT4,RFX3,RPE,SPIN3,ATP8B4,TCP11L1,PAQR6,SATB1,FNIP1,DOCK10,FBXO11,CDK5RAP3,CEP68,FBXW11,TIE1,TTC3,ZNF711,PRDM2" Coexpression M7776 Genes up-regulated in macrophages after M. bovis BCG infection: 24h versus 48h. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "ACLY,ARHGAP20,PTBP2,MAP7,CBLN1,CLTC,MAGED1,ZNF385A,CLOCK,CPEB2,HIPK3,VPS13B,EPHB1,SCML2,FKTN,GORAB,AHCYL1,GCK,GFAP,AIFM3,GRIA2,NCKAP1L,CPT1C,SCIN,INSM1,KIT,L1CAM,MAOB,ZNF655,FAT3,REV3L,SUGCT,RTN1,BTBD3,POGZ,ERBIN,SEMA4A,CAMSAP2,AHCYL2,TIMP4,TJP1,ASXL3,UBC,ZNF184,WNK1,PARP11,NUP214,KLHDC1" Coexpression M4416 Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated memory CD4 [GeneID=920] CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 8.52E-04 1.00E+00 8.93E-03 8.87E-02 48 198 "ACTN1,ACTN2,AQP6,SEMA4G,ATM,BTK,WASF1,CACNB4,ARHGAP33,CACNA2D2,PPT2,SEC31B,FEZ1,GREB1,DBT,KIAA0753,PHF20L1,POLR1B,SEMA6C,PRELID3A,ADGRA3,ADAP1,SPACA9,GRIK5,KAT7,HAPLN2,HPSE2,KCNMA1,NUMA1,PAK3,PDE1B,CDK14,NLGN3,TNPO2,LRRN3,PRKAR1B,PTPRO,BEND5,SATB1,SCN2B,SH3BP2,COA1,MAPK8IP3,DNMBP,TCF7,TLL2,CABIN1,ZMYND8" Coexpression M9325 Down-regulated 'cooperation response genes': responded synergystically to the combination of mutant TP53 and HRAS [GeneID=7157;3265] in YAMC cells (colon). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.67E-04 1.00E+00 9.07E-03 9.01E-02 21 67 "ABAT,MTUS1,COL9A3,ZNF385A,ARHGAP24,DAPK1,SEMA3D,ELAVL2,ATP8A1,NBEA,RAB40B,PLTP,DUSP15,SATB1,FHOD3,SCN3B,BEX1,TEX15,HEY2,RPRM,STMN4" Coexpression 17761949-TableS1 Human Kidney_Doghman07_98genes GeneSigDB 8.67E-04 1.00E+00 9.07E-03 9.01E-02 21 67 "NR0B1,AKAP7,RIMS3,EML1,ETV1,FGF13,SHISAL1,FXYD6,NPTX2,ENPP2,SYTL2,PTPRZ1,EMID1,HES6,TNFRSF19,PJA1,ACSL6,CDH22,TMOD1,DAAM2,VAV2" Coexpression 19096012-TableS5 Human Viral_Chetaille09_666genes GeneSigDB 8.77E-04 1.00E+00 9.16E-03 9.10E-02 120 590 "ACLY,GRAMD1B,MTUS1,PLA2G6,TAOK1,ALAD,OGT,PARG,APBA2,KCNAB2,APP,MADD,ATP1A1,ATP2B1,ATP6V0A1,CFLAR,SGCE,CANX,CH25H,ARHGEF1,ARHGEF2,CDC27,JAM2,TPP1,AKAP7,SUMF2,IFFO1,NSL1,SEC31B,CREM,SOCS5,PDE4DIP,APPL1,TM9SF4,IP6K1,SIRPA,HEPH,HP1BP3,DOCK2,ECM2,EDNRB,ANKRD46,FCF1,SORBS3,EIF5,PLEKHA1,HSD17B14,EPS8,ARMCX1,EFEMP1,ZNF589,AMOTL2,UBE2E3,SEC23B,SEMA4D,OGA,GAA,NCKAP1,GATM,GLUL,GPM6B,BTN2A1,CLASRP,GUCY1B1,NCKAP1L,ITGAV,IPO5,MAP4,MARK3,MATN2,MBD1,MEIS2,NDUFA5,PBX1,PCMT1,PLCB2,TNPO2,POLG,PTPA,PPP3CB,PKIA,VPS13C,RIPOR1,BEND5,BSDC1,ZNF532,EXD2,S100B,SAFB,SUPT20H,WDR47,SEPHS1,CDK5RAP3,KBTBD4,KIF21B,GLT8D1,NXT2,MAPK8IP3,GANAB,SEMA4A,CAMSAP2,ATMIN,EHBP1,CRTC1,SIK3,SIRT1,TGFBR3,CBX5,ZNF384,TRIO,TSC1,SSBP2,TUBB2A,UBTF,ZNF189,ZFAND5,TUBA1A,SNX27,WIPF2,PLSCR4" Coexpression 20068109-SuppTable3 Human Breast_Horlings10_271genes GeneSigDB 8.80E-04 1.00E+00 9.18E-03 9.12E-02 57 245 "ZFAT,TNRC6C,DNAH17,CHRD,BCHE,COG1,PDE4DIP,FAM169A,PITPNC1,CCDC3,ABCC5,EBF1,PHF20L1,EIF4G1,VPS13B,ABCA8,AMZ2,ATP5PD,KHDRBS3,SYT17,SEPT9,KIAA1958,GRIN2D,HAS2,ZHX1,TTYH2,MATN2,GIT1,SERPINI1,PNMA3,LRP12,PPP2R5E,DEF8,TMEM104,MARCH1,RPL38,SEC14L1,TRA2B,FAM102A,SYBU,NLGN1,SLA,SOX2,TNIK,ERBIN,JMJD6,SYN2,EXOC7,KCTD2,WBP2,TRPS1,TUB,FLRT2,EMX2OS,KCNAB1,MRPL47,FXR1" Coexpression M2043 Cluster f: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.91E-04 1.00E+00 9.29E-03 9.23E-02 18 54 "ACTN2,ANK2,DCLK1,CHGB,CHRDL1,EEF1A2,ABCA8,FHL1,IGF1,MYBPC1,PKIA,SLN,ZFPM2,THBS4,TPM1,TPM2,TPM3,SYNPO2" Coexpression M6321 Genes down-regulated in spleen from DUSP1 [GeneID=1843] knockout: control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 9.09E-04 1.00E+00 9.47E-03 9.40E-02 42 168 "ACTN1,ADCY6,ADD3,PITPNM2,USP28,TMEM108,GPR146,MAP4K4,ABCG1,SIPA1L1,HDAC4,TOX,PLEKHO1,CHST15,SYNCRIP,RAPGEF6,SESN1,RAPGEF4,GSTT2,PIK3C2A,TMIE,RETREG1,PACSIN1,SIDT1,SNRK,ZYG11B,SATB1,SELL,ST6GAL1,ST8SIA1,SCMH1,TET1,TRERF1,CLASP2,TBL1X,TCF7,ZEB1,ARHGAP9,SSBP2,TTC3,CERS6,JMJD1C" Coexpression M2938 Genes up-regulated in CD8 T cells: naïve versus undergoing deletional tolerance. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-04 1.00E+00 9.50E-03 9.44E-02 38 148 "USP28,APC,TNRC6C,HDAC4,TOX,KBTBD11,SNX29,RASGRP1,PLEKHA1,LRRC23,SLC43A2,CHST15,SESN1,TDRKH,RAPGEF4,ADAMTS6,IL6ST,SMAD1,SIDT1,EML5,CNTNAP3,ST6GAL1,DZIP1,TET1,MBD5,KIF1B,MAPK8IP3,CEP68,FAM168A,MGRN1,TCF7,SYNE1,TGFBR3,KAT6B,SSBP2,TTC3,MICU3,MPPE1" Coexpression M1188 "Genes up-regulated in MDA-MB-231 cells (breast cancer, mutated TP53 [GeneID=7157]) undergoing aberrant mitosis and necrosis after treatment with 2 nM docetaxel [PubChem=148124]." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.48E-04 1.00E+00 9.82E-03 9.75E-02 24 81 "AGT,N4BP2L1,ST3GAL5,GYG2,BTRC,CRLF1,DCT,LPAR6,FOLH1,IQGAP2,IFI16,KLRC3,PIK3R1,PXK,RASGRF1,SGK1,SLC6A8,WSCD1,ZFP90,SLC35G2,TGFBR3,SSBP2,VLDLR,WRN" Coexpression M12895 Genes down-regulated in basal-like breast cancer cell lines as compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.53E-04 1.00E+00 9.82E-03 9.75E-02 17 50 "APLP1,RNF182,AK5,ARNT2,EDIL3,FLNC,PNMA2,GRB10,MMP16,PFKP,RGS7,ARHGEF40,ZCCHC24,ZEB1,TRIO,TUBB2A,SCG2" Coexpression M5541 Genes up-regulated in comparison of B cells versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "MARCH3,ZBTB10,CACNA1A,REPS2,CHRM4,LY86,COL9A3,SMARCAL1,CHD1L,RUBCN,CYBB,E2F6,SIDT2,RBM12,EPB41L2,TLR7,DLL3,SYT17,GATM,MSL3,RNFT2,IRF8,MEF2C,CD200,NASP,CDK14,FA2H,PTPRN2,ZDHHC14,TMEM156,MAPK12,SCN2A,SEC14L1,SHMT2,ST6GAL1,SLC2A5,ZC4H2,ZC3H4,SYPL1,CUX2,USP22,KCNE5,TST,MICAL1,CLIP2,LAT2,ZNF154,SEMA3B" Coexpression M9701 Genes down-regulated in macrophage differentiated by: CSF1 [GeneID=1435] versus CSF1 [GeneID=1435] and IL27 [GeneID=246778]. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "RBM10,MTUS1,MRTFA,DGKZ,CHID1,CFLAR,ZNF555,DIRAS1,CALM1,SYT6,RAB33A,TJP2,RCHY1,IGDCC3,NCOR2,IPCEF1,CST3,KIAA0040,TBC1D5,KLHL3,BLOC1S6,SMG7,EIF4G1,ECSIT,CELF1,STARD10,OS9,GIT1,NRDC,PKM,PLEC,MAPK7,ROGDI,KCTD17,RPRD1A,SBF1,SLC9A5,IQCE,NEU4,CABIN1,TTPA,NPDC1,CRB2,INTS3,MVB12B,PHTF2,ACTR3B,ZDHHC20" Coexpression M9423 Genes down-regulated in TCF7 [GeneID=6932] knockout: DN3 thymocytes versus T cell lymphoma cells. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "APBB2,GAS7,LGR5,ADAM23,BARD1,WASF1,CD38,CDC27,DGCR9,COL9A2,CLOCK,SNPH,RIMS3,ZEB2,MYEF2,DLG3,CELSR3,AASS,EPS8,CAMSAP1,FOXF2,TACC2,SMC2,STAU2,IQGAP2,ATP8A2,GJB1,GRM5,GUCY1B1,ARHGAP19,KCNJ10,AFF1,MPP2,GPSM2,PLXNB1,PTPRE,ERI2,SEC14L1,MYO16,ZCCHC24,ITPRID2,JMJD6,SYNE2,DMXL2,GORASP1,TOM1L2,SLC30A3,PHTF2" Coexpression M6574 Genes down-regulated in dendritic cells: bone marrow-derived versus follicular. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "AS3MT,ARID1A,ADCY6,EP400,PHYHD1,ARRB2,RASL11B,RGS11,CLDN10,ARHGEF1,CDK11B,CHRNB2,GUCD1,SEZ6L2,RASGRP1,EPB41L1,DENND4A,SH3YL1,TBC1D16,FCGRT,TACC2,GGT5,GOLGB1,RAPGEF4,RNF165,GUCY1A1,ATG4C,ZDHHC15,IL11RA,KCNH2,FGFBP3,SRSF12,PPM1L,PLP1,C19orf57,PRKCZ,RAD52,RPRD1A,EXD2,ZFP2,GALNT10,RASA3,TET1,MAPKBP1,STX1A,SMUG1,PARP6,FRMD6" Coexpression M8343 Genes up-regulated in activated versus induced T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "ABAT,ADCY8,SLC12A5,OSBPL8,CASK,USP2,KIAA1549L,CNGA3,SLC4A7,ATRNL1,VCAN,CNTNAP2,DZIP3,GIT2,SEMA3D,ELAVL4,SIRPB1,F3,DLC1,FLT1,ARFGAP2,KHDRBS3,WASF3,RAB40B,GUCY1A2,WIF1,HPCA,RBPJ,KCNA1,KCNN3,NRDC,PGAM2,ST8SIA5,LRRN3,PTPRE,PTPRN2,PEX2,SELL,HSPA4L,ST6GAL1,SLA,SMARCC2,PALLD,ZFR2,TCF4,TP53BP2,WRN,NDRG4" Coexpression M4142 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "CLK4,KDM5D,NDRG2,SPOP,APAF1,CHRD,ATP2A2,RGS9,HCN2,OSGIN2,CARS,CFL2,SYNPR,PPT2,HECTD1,TBPL1,BOC,ZFYVE16,RUSC2,DPYSL2,FEM1B,CALCRL,ACSL4,SYNCRIP,UFM1,GABRG2,TRAF3IP2,FICD,ITGAV,ITPKB,JAK2,GPR88,OPA1,P2RX7,PDPK1,GPR85,PMP22,MAPK8,QRICH1,USP47,RAD17,SALL1,SH3BP2,SLC6A8,ITPRID2,SATB2,PITPNB,PMEPA1" Coexpression M8398 Genes down-regulated in brain microglia versus spleen CD8+ dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "SLC12A5,ANK1,PPFIA2,APBB1,APOC1,PLA2G4C,ARSF,CHRD,CCDC181,C5,CD38,DLGAP2,LY86,PPP1R16B,GREB1,CTNND1,CTNND2,IP6K1,RHOBTB1,ABCC9,FCGR3A,FOXF2,GAB1,GBX2,GCNT2,ADAM28,GFRA2,GJB1,RAB30,GRM7,GUCY1A2,IGF1,LSS,MATN2,NEUROD2,NPY,PLCL1,PTN,RBBP8,RNASE1,FRMPD1,SLC4A3,SLCO1A2,SATB2,CDH22,TPM1,TRPC1,FLRT1" Coexpression M7718 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 1h. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "PLA2G6,KIAA1614,SPTBN4,CACNA1I,CAMK2A,SYNGR3,ARHGAP33,LARGE1,MAGI1,CHRM4,PICK1,CSF1,DAPK3,DPP6,SORBS3,STX2,FDFT1,PRKAG2,NEU3,GPM6A,GSTM5,IL6R,ITGAV,KCNJ5,KCNJ9,KCNN1,KCNQ3,HNRNPM,NEFH,NEUROD1,NLE1,SUSD4,RFX2,GSTCD,SEC14L1,ARHGEF40,CDK5RAP3,LIMCH1,IZUMO4,ARC,CAMTA1,TCF7,TCF12,CRTC1,TP53BP2,CFAP298,ZNF142,TUBA1A" Coexpression M7799 Genes down-regulated in monocyte-derived dendritic cells infected by: SIV versus HIV and SIV. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "TEX22,DNAH17,CBLN1,CBS,ADGRG1,PPP6R2,CENPL,ZBTB24,B3GAT3,FAM135B,SLC43A2,DNAJC27,OLFM1,NBEA,ZNF605,PNMA2,SEPT9,LUZP2,GNAS,GPR19,BRINP3,KCNA1,KCNF1,KCNQ3,MARK1,PKIA,TMEM104,PTPN13,ROGDI,RASGRF1,RGS10,MRAP2,FAM19A1,SCN8A,TNFRSF19,IL17RB,SLC6A1,YPEL4,SLC12A2,MTERF2,ATF7IP,CYB561A3,TEK,GZF1,TPM2,PDIA2,ATP6V0E2,AMZ1" Coexpression M4811 Genes down-regulated in comparison of B cells versus erythroblasts. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "AP1B1,GAS7,TTLL9,CDK5R2,CARS,TMEM59L,FADS2,VCAN,TCAF1,AK5,ARRDC4,TMEM132C,USP21,PNMA2,NRG3,C15orf41,ALDH1L1,DHRS4,LOXL3,FUT10,GPR26,TPPP,MAP4K5,NXPH3,IBA57,SMAD9,PPM1L,MSR1,MTR,OGDH,PAX6,TMOD2,TMIE,KCTD15,PLCD1,CRTAC1,ZFP2,KIF27,SNRPN,WWC1,VWA3A,HHIP,PARD3,KCNE5,LYPD6,NAV3,ST7,VANGL2" Coexpression M3239 Genes up-regulated in comparison of naive B cells versus IgM-memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "ADRB2,MAP4K3,DGKD,CASK,CAPRIN2,BRINP2,KYAT1,DGKI,LARGE1,TCEAL2,KIAA0040,MYEF2,MFAP3L,PDCD6IP,HIPK3,EFNB3,PHF20L1,RASGRP2,EYA1,WAC,TUBB3,CORO2B,CHST15,BAIAP2,MSTN,ZNF276,BACH2,LINC00667,KCND3,LIG4,MEIS2,CD200,BCO1,NFYA,OPA1,PCDH9,RASGRF1,SATB1,SH3BP2,RIMS1,PBLD,EPB41L3,FAM208A,AHCYL2,ZFPM2,TRIO,SSBP2,DPF3" Coexpression M6266 Genes up-regulated in medullary thymic epithelial cells (mTEC) with CD80 [GeneID=941] high: AIRE [GeneID=326] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "CPNE2,WDR35,PPFIA1,PKP4,PDXK,ATP1B3,ARHGEF1,ZMYM4,CDC42BPB,LRIG1,TM9SF4,GSDME,SMG7,MED12,DOCK2,TSPAN5,FAM198B,RPS6KC1,ATP8A1,FOXM1,TUBGCP4,KIAA1958,GYG1,IDH3B,IBA57,VWA5A,MYO6,MYO7A,CNOT4,NPY,ETFRF1,SMIM7,PRKCB,SPDL1,ZIK1,RAB3IL1,TMEM206,RXRA,ZSWIM8,STAC2,AHCYL2,LRRC8A,TRIO,TTC3,FLRT2,AMZ1,TMEM178A,RGS7BP" Coexpression M2917 Genes down-regulated in skin from 129S1 mice after injection of: control versus Trypanosoma cruzi (strain Y). MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "ADORA2A,ESYT2,GPRASP2,BIN1,ASCL1,ATP1B3,MTMR3,CAST,CD81,MAGED1,ZNF521,BRINP1,ARMCX4,OLIG1,SLC12A6,SRRM1,CLVS1,PRKAG2,FHL1,MEX3B,ZBED3,TPPP3,STON1,LPAR4,PTPN5,ADAMTS6,ITGA7,KCNJ9,KIF5C,NAP1L3,OCRL,PLCL1,SMOX,PROX1,PTPN13,RALGDS,RXRA,SELL,SHC4,CCDC92,TAB2,SLC37A2,AHCYL2,DNAH7,PITPNB,TOM1L2,SPHK2,PRDM2" Coexpression M5222 Genes up-regulated in comparison of dendritic cells (DC) exposed to 50 worms/well B. malayi versus those exposed to 5 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 9.57E-04 1.00E+00 9.82E-03 9.75E-02 48 199 "ADD1,SLC12A5,FAM131A,SHROOM2,ATP1B3,ATP6V1G2,CACNA1D,CALB1,CHGB,RAB33A,MICAL2,CTH,COPS7A,KIAA0319,SV2A,DMD,ADGRV1,ACSL4,BAIAP2,DCTN2,GLDC,FERMT2,LILRA2,GRIN2C,AP4S1,ATXN2L,MKLN1,PDE4B,HERC2P3,FAM216A,MED1,MAPK9,MAPK10,SLC25A36,ZC3H14,TRA2B,SLC22A4,SORCS3,ZCCHC24,ZSWIM8,PEG10,CAMTA2,KIAA1107,TCEA1,DNAH7,AP4E1,TPD52L2,SCG2" Coexpression M11383 "Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 16 h time point that were not up-regulated at the previous time point, 14 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.69E-04 1.00E+00 9.93E-03 9.87E-02 53 225 "PPFIA1,N4BP2L1,FUBP1,BTRC,INA,CREM,FAM169A,USP6NL,DLG3,DYNC1I1,DTNB,E2F5,E2F6,YAF2,ENO2,TESK2,OLFM1,CAMSAP1,KHDRBS3,MPP6,GATM,TUBGCP4,STARD3,GPR37,KCNH2,KLHL23,KCNK1,KPNA5,MAT2A,NEFM,NPTX2,PAK3,PDE4D,ABCB1,PLCL1,SNRK,PTHLH,PTPRE,PLEKHB2,RGS3,HSPA4L,WDR47,SLC6A8,SLC15A2,SON,NXT2,NACAD,TTBK2,NR2C2,VLDLR,ZNF45,SLC30A4,ST7" Coexpression 15805246-Table3 Human Esophagus_Hu05_33genes GeneSigDB 9.76E-04 1.00E+00 1.00E-02 9.93E-02 11 26 "GALNT13,GPR158,PKP4,GRIN3A,EPHB1,MYH3,PACSIN1,KDM4C,PLCB1,SYNE1,PSD3" Coexpression M4289 Genes down-regulated in comparison of control conventional dendritic cells (cDC) at 2 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 9.86E-04 1.00E+00 1.01E-02 1.00E-01 46 189 "CLK4,KDM5D,KMT2C,NRXN2,MYL6B,AHCTF1,ZFYVE16,SLC25A5-AS1,TMEM132E,LINC-PINT,MTSS1L,DENND4A,CEND1,PSMA3-AS1,CEP78,POLR1B,MEX3B,BRSK1,GK,GP1BB,BTN2A1,GPR45,LRRCC1,KCNQ2,MAN2A2,MARK3,MAT2A,CHST6,ADAM11,CNOT4,HERC2P3,ZNF655,RAD52,MEG3,FUZ,ST8SIA1,CDK5RAP3,ANKRD36,CHST8,TNR,METTL3,MICAL1,ZIC1,ELFN1,ZNF177,SNX27" Coexpression M12144 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 48 h time point that were not down-regulated at the previous time point, 24 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 9.88E-04 1.00E+00 1.01E-02 1.00E-01 104 502 "ACHE,ADCYAP1R1,ADD1,PLA2G6,ANK1,EP400,CDC14B,CDK13,ASCL1,ASPH,BCHE,CA12,CACNA1A,CACNA1E,BRSK2,RUNX1T1,AP4M1,LOC730101,DLGAP1,CDR1,CNOT8,FADS2,CRMP1,MICAL2,PPP6R2,FRMPD4,YTHDC1,DCTN1,SEC16A,DTNA,ECM2,DUSP9,ABCC9,SNX29,PLXNC1,BSCL2,EMX2,EN2,RCAN2,RASGRP2,ERBB2,ETV1,EFEMP1,FGF13,FGFR1,FOXO3,FOLR2,ATP2C1,GABRA1,GFAP,PRUNE2,GPR12,GRM8,HAS2,PTGDR2,ITPKA,KCNK3,LAMA2,LIMS1,MAP2,MATN2,MMP16,MTR,SAMD14,LYRM9,NAP1L1,NAP1L3,NEK1,NTRK2,DDR2,PBX1,ENPP2,PLCD1,PLP1,MBOAT7,MASP1,PTPRD,PTPRO,RAB5B,RAD52,IQSEC3,RNASE1,RNH1,ROM1,SH3BP2,FAM214B,ZHX3,NMNAT2,SPP1,SPTB,NFASC,ST5,MGRN1,WSCD1,TJP1,TK2,KAT6B,TPM4,TRIO,UBE3A,SLC13A3,ZSCAN26,SSPN,IFT88" Coexpression M469 Genes up-regulated in RAW264.7 cells (macrophage): control versus stimulated with IFN-b. MSigDB C7: Immunologic Signatures (v6.0) 9.98E-04 1.00E+00 1.02E-02 1.01E-01 33 124 "ADARB2,ADGRF5,COL11A2,PABPC5,FABP7,FOXO3,GFAP,CBX1,LPAR4,PCLO,IGSF21,NCKAP1L,ELOVL5,METTL21A,KIT,SHC3,MSR1,NRBP2,RSPO2,NEXMIF,NELL2,NEUROD1,TMIE,PLXNB3,PMP2,SLC22A23,MARCH1,LGR4,ZFP30,SPATA7,PEG10,NEK4,FSTL5" Coexpression M2915 Genes down-regulated in skin after injection of Trypanosoma cruzi (strain Y): wildtype (BALB/c) versus INFG [GeneID=3458] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.98E-04 1.00E+00 1.02E-02 1.01E-01 33 124 "TKTL1,NDRG3,ADARB2,ADCY2,SORCS1,BBOX1,CDC42BPA,ANK2,FGF17,ENTPD6,REPS2,CRY2,SEC24C,CNIH3,EML1,RASGRP2,SYT17,BRD8,GPR12,GSN,HMGB1,LIMS1,MN1,GDPD2,PEX2,MAP6D1,TMEM156,KDM4B,ST5,CAMTA1,RALYL,SIRT1,VAV1" Coexpression 15860665-Table1 Mouse Leukemia_Muntean05_74genes GeneSigDB 1.01E-03 1.00E+00 1.03E-02 1.02E-01 16 46 "MRTFA,TMCC2,ELAVL2,RASGRP2,TUBB3,LIFR,MEST,NPY,SERPINI1,PLP1,GRAMD1C,RELN,SNCA,NACC2,P2RY12,PRRT4" Coexpression M6764 Genes down-regulated in cells from Flt3L Melanom injected mice: splenic DEC205+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.01E-03 1.00E+00 1.03E-02 1.02E-01 34 129 "PNMA8B,HECW2,MYH7B,JAZF1,NOG,ELN,APC2,TMEM74,FGFR3,GABRA3,AIFM3,GNG3,ADGRA3,GUCY1A2,TOX2,ZIC5,NRBP2,HS6ST3,NPTX2,BEST3,SDK2,MAGEL2,PTN,SLC6A15,KIF7,LGI3,NFASC,STXBP1,SYT5,DMXL2,CLEC2L,REEP1,CADM2,DNALI1" Coexpression M6881 Genes down-regulated in monocytes after HCMV infection: untreated versus BAY 11-7082 [PubChem=5353431]. MSigDB C7: Immunologic Signatures (v6.0) 1.02E-03 1.00E+00 1.03E-02 1.02E-01 43 174 "AXIN2,SYT13,SFMBT2,EIF4G3,PRMT9,CD81,ZMYM4,MAP4K4,MAGED1,CLOCK,SIPA1L1,CTNND1,PPP6R2,YTHDC1,FAM107B,MBNL2,GPHN,PTK2B,NEU3,GFRA1,FUT10,AGFG1,LRRCC1,IL6ST,JAK2,HECTD2,NF1,OCRL,PGAM2,SH3KBP1,PEX2,SLC25A36,CLIP1,LMBRD1,USP33,UHRF1BP1L,CAMSAP2,MGRN1,ARHGAP9,ZNF106,TTC3,ZBTB38,DHX33" Coexpression M406 Genes down-regulated in of bone marrow progenitors: 4- versus 8-day cultures. MSigDB C7: Immunologic Signatures (v6.0) 1.03E-03 1.00E+00 1.03E-02 1.02E-01 35 134 "SERPINA3,MTA3,OSBPL6,TAOK1,USP35,CDC14B,MIER1,CAPRIN2,RNF182,FMNL3,ARHGEF1,ZMYM4,SOCS6,SLC4A7,PNMA2,LPAR4,DIDO1,GUCY1A2,HSF2,DISP2,XRRA1,PGAM2,ST8SIA5,LRRC49,DEF8,SNRK,ZMAT4,FBXW7,LGR4,SLC37A2,ACTR6,TRPC1,BEST1,WRN,RTN4" Coexpression M465 Genes down-regulated in splenocytes from OT-1 TCR transgenic mice: control versus IL-12 treatment. MSigDB C7: Immunologic Signatures (v6.0) 1.03E-03 1.00E+00 1.03E-02 1.02E-01 35 134 "APAF1,USP37,SHROOM2,ARHGAP5,CBFA2T2,HINFP,PDE4DIP,CX3CR1,TBC1D5,CEP170,CPEB2,DNM1L,GOLGA7,POLK,FOLR2,POMT1,GPR34,PRDM5,ARHGAP12,NFYA,RFX5,ACER3,LGR4,SCN7A,ZHX3,UHRF1BP1L,SAMSN1,LARP4,NEK4,FBXW11,TBL1X,TRO,USP1,NAV2,HNRNPA3" Coexpression M6386 The 'group 4 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-03 1.00E+00 1.03E-02 1.02E-01 68 305 "SERPINA3,ABAT,ADD3,ADORA1,CA12,CALB2,LARGE1,LRWD1,CIART,CHN1,NRXN3,TPP1,COL4A5,TRIM69,LRIG1,ATRNL1,VCAN,GREB1,NOS1AP,MED24,DSCAM,EGR3,RASA4,DLC1,FDFT1,PRMT5,OLFM1,TMEM164,MAD2L2,GLS,KCNMB4,GRIK3,ARHGAP36,ELOVL5,HNMT,IGSF1,TUBB2B,ZNF385B,JAK2,KCNJ3,LAMP2,SYTL4,MAPT,LYPLAL1,KCTD6,AFF1,PIK3R1,FTO,APTX,ELOVL2,RBBP8,PRRT2,RFX5,RPRD1A,ELP2,IL17RB,SFPQ,SYBU,SNRPN,MYO16,SPART,CEP68,TBL1X,SIK3,ELP5,TST,SGK3,CADM1" Coexpression M12176 Genes down-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-03 1.00E+00 1.03E-02 1.02E-01 50 210 "ABHD6,C1QTNF3,PLA2G4C,ASPA,SLC4A4,ST3GAL5,LDB2,CD81,RAB33A,FAM189A2,MYRIP,KIAA0040,CX3CR1,HDAC9,DAPK1,MFAP3L,NR1D2,ATN1,RCAN1,FRY,BSCL2,AMOTL2,DKK3,GATM,GHR,GLUL,SYNPO,IGF1,IL6ST,KCNK1,KHK,LAMA2,PACRG,ZNF862,NBL1,PDE2A,SNRK,PTPRB,FAT4,RASGRF1,LIMS2,SLC6A1,NAXD,ZCCHC24,ZSWIM8,ZEB1,TNS2,TJP1,TK2,TST" Coexpression M2456 Genes requiring MLL [GeneID=4297] for H3K4me3 and expression in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.03E-03 1.00E+00 1.03E-02 1.02E-01 65 289 "AGT,ASPA,ATP2B1,CACNA1G,CACNA1A,CDO1,JAM2,SLIT2,VAX2,ARHGEF6,ABI3BP,GAL3ST1,GDA,HDAC9,TOX,RABGAP1L,EBF1,FAM13A,EGR3,TMEM35A,CDHR1,ETV1,F5,FABP7,PNMA2,DKK3,GPM6B,B4GALNT4,GRB10,GSTT2,FRMD5,HLF,NEGR1,HTR2A,ITIH2,KCNA4,KCNC2,PPM1L,CCDC80,RSPO2,NFIA,TREM2,PAX6,CNNM2,LAMA1,PTHLH,RAB3IL1,ZCWPW1,MEG3,HOGA1,SCP2,KIF21A,SHC4,FNDC3A,SLC8A3,EFHD1,SOX5,ARHGAP26,SMOC1,ANO4,TBX15,PCDHB7,TGFBR3,ZIC2,STOX2" Coexpression M16927 Genes up-regulated both in group C and D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.04E-03 1.00E+00 1.03E-02 1.02E-01 36 139 "BCL7A,DIRAS1,SCARB1,CNN3,AKAP12,CTH,ZEB2,GSDME,FARSB,EBF1,EPS8,BRD8,GLS,NUDT21,CECR2,DDX19B,BACH2,KLC1,NAT8L,MARK3,NAP1L1,PRKACB,DIRAS2,PTK2,KIF7,TMEM206,ITSN1,PPM1E,CLASP2,CEP68,STXBP1,TRIM2,TMOD1,TPM3,CFAP298,AMZ1" Coexpression M2887 Genes down-regulated in epithelial breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.04E-03 1.00E+00 1.03E-02 1.02E-01 37 144 "TTYH1,ASPHD1,ASIC1,HCN2,CACNA1A,MYOM2,ELMO1,SV2B,DTNB,EDIL3,FGFR3,FGR,POLL,GP1BB,HPR,KCNJ3,KCNQ3,MYH7,NOS1,P2RX7,PBX1,CDK18,PDE3A,ABCB1,POU3F2,SIDT1,SYNDIG1,PAQR6,SCN7A,PPM1E,KDM4D,SLC8A1,TEX15,RUNDC3B,TRIM9,SLC30A3,ZNF37BP" Coexpression M1238 Genes hypermethylated in at least one of the lymphoma tumors of transgenic mice overexpressing TCL1 [GeneID=8115] in germinal center B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.04E-03 1.00E+00 1.03E-02 1.02E-01 19 59 "OSBPL6,PCDH10,PKP4,RUNX1T1,NRSN1,KIAA0408,FOXG1,FAM49B,CLVS2,SAMD5,NCAM1,MDGA2,PTPRD,FAM184A,FIGN,SOX1,SOX3,AJAP1,ZIC3" Coexpression M3395 Genes down-regulated in non-apoptotic tissues (fetal liver) after MDM4 [GeneID=4194] knockout. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.05E-03 1.00E+00 1.03E-02 1.02E-01 106 514 "ABCF1,ADD3,ALCAM,PPFIA1,ARHGAP5,DACT3,ATP2B1,ST3GAL5,FUBP1,GPC2,PRC1,CDC27,CDH2,RCBTB2,FADS2,ABCG2,QKI,COL9A1,IGDCC3,CLIP3,CSF1R,CSNK1G3,MATR3,DBT,HP1BP3,HIPK3,FEM1B,SH3GLB1,EFNB3,PHF20L1,MBNL2,EIF4G1,EPB41L2,ATP8A1,SEC24B,OLFM1,AGAP3,FOXM1,SGIP1,USP16,UFM1,STAMBP,CELF1,ZMYND11,USP19,GHR,BRD8,SPIN1,GLYR1,FERMT2,CNTRL,GRB10,GUCY1A1,HMGCR,MSL1,IGFBP1,IL6ST,ITIH2,MAOB,MBD1,MDM4,NNAT,ODF2,PDGFRA,GNG2,PIK3R1,CCSER2,PRRX1,ING3,PPM1B,RELN,WBP1L,PTPRG,RNF220,SATB1,ATXN2,SFPQ,ATF7IP,SPHKAP,RCOR3,SON,SP4,KIF1B,SPART,TROVE2,EPB41L3,ERBIN,STAU1,APOM,ANKRD28,FBXW11,TBL1X,TBX15,TCF4,TCF7L2,USP22,ZNF106,SLC44A1,CBX5,RBFOX2,TPM4,PITPNB,XPO1,ZFAND5,PCBP4,DPF3" Coexpression 17850661-TableS4 Human Breast_Yau07_103genes GeneSigDB 1.06E-03 1.00E+00 1.03E-02 1.02E-01 23 77 "ACADM,OSBPL8,DST,FAM189A2,LRIG1,EGR3,GATM,PCSK1N,PTPRT,KCNK1,KCNMA1,MAOB,MAPT,MATN2,TREM2,RTN1,SPART,CLSTN2,SYT1,PSD3,TGFBR3,TRPS1,PLSCR4" Coexpression M2438 Genes whose DNA methylation differed between primary ALL cells (acute lymphoblastic leukemia) and normal peripheral blood samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.06E-03 1.00E+00 1.03E-02 1.02E-01 23 77 "CLOCK,SUSD5,SMC2,KHDRBS3,FAM184B,NFU1,AGFG1,HSF2,KCNK2,SFXN5,LRP1B,NASP,NFIA,ZNF827,PROX1,MRAP2,HSPA4L,MCF2L2,RUNDC3B,RPRM,FSTL5,SMARCAD1,FBXO36" Coexpression 17409456-Table4 Human Skin_Alonso07_22genes GeneSigDB 1.07E-03 1.00E+00 1.03E-02 1.02E-01 9 19 "CDH10,CHN1,OLIG2,KIT,MITF,PCDH9,PDGFRA,PMP22,PTPRZ1" Coexpression 19724859-Table3 Human Breast_Folgueira09_26genes GeneSigDB 1.07E-03 1.00E+00 1.03E-02 1.02E-01 9 19 "PTBP2,SPAG9,GALC,GIT1,KCTD15,METTL3,VLDLR,ZNF19,ZNF189" Coexpression M6664 Genes up-regulated in bone marrow-derived macrophagesat 180 min stimulation by LPS: IL6 [GeneID=3469] knockout versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "APBB2,ST3GAL5,CACNA1A,CLDN10,EPS15L1,HOMER3,COX4I1,CRYM,GALNT9,SDC3,APPL1,DAPK1,PARD6A,GTF2IRD2,NBEA,MSANTD4,NCKAP1,ZNF276,LNX1,GOLGB1,LPAR4,GRM3,PADI2,IL11RA,ITGAM,KCNJ3,VWA5A,MAP6,MEF2C,NFIX,NUCB2,TBC1D25,PIK3C2A,SCHIP1,CNNM2,BSDC1,TRIM68,LRRK2,RYR1,FOXRED2,SLA,ZNF334,LARP4,ACSBG1,PRRC2C,PSD3,CLDND1,ZNF32" Coexpression M9842 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "MTA3,MRTFA,MAP4K3,RASL11B,ALDH7A1,STOML1,ARHGEF6,ACBD5,ARHGEF10,SDC3,PHF14,KBTBD11,GNE,WDPCP,RASA4,ASB3,EVL,SEMA4D,HVCN1,STAU2,PRRC2B,ATE1,LIFR,GPR155,MARK3,MATN2,ABCB1,POU6F1,MAPK9,GRAMD1C,PLEKHB2,RAD52,RIC8B,RNASEL,DCUN1D2,RASA3,MYO18A,CHD9,CDK19,ITPRID2,NCDN,WDR7,KCTD2,TPD52,P2RY12,C12orf4,UBE3B,CERS6" Coexpression M7515 Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "FMNL2,FGD2,MYOM1,CBFA2T2,LY86,ELMO1,TMCC2,DOCK2,LPAR6,CALCRL,RASGRP2,RCSD1,EXTL2,IQGAP2,INPP5K,SESN1,GHR,PADI2,NCKAP1L,IRF8,NIM1K,IL11RA,STMN1,INSYN2,SMAD1,TM6SF1,MEIS1,MITF,PDE4B,CDK14,SLC25A23,SPATA6,SH3KBP1,C1orf54,SPP1,BEX1,CEP68,KAZN,MCF2L,TLR4,TPD52,AMZ1,PCBP4,DOCK8,CERS6,FRMD6,IFT88,SPATA13" Coexpression M9310 Genes down-regulated in follicular B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "CADPS,DYNLL1,SNAI3-AS1,ARHGEF7,SCARB1,FBXO7,GAL3ST1,CSF2RA,CST3,KIAA0040,GIT2,SIRPA,DLX1,EPB41,TLR7,GMPR2,TAOK3,TCERG1,ADAP1,AP4S1,SLC2A6,HMGCL,ICA1,IDH3B,STXBP5,MRPL42,NASP,NFYA,NINJ2,TREM2,GPSM2,POLR2F,PTPRO,ZSCAN2,FEZF2,CCDC82,MCMBP,SCN4B,HES6,TRIM67,FCHO1,AKNA,TF,MTMR14,PIK3R5,MEAF6,LAT2,ATP6V0E2" Coexpression M9313 Genes up-regulated in follicular B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ESYT2,DGKD,PHYHD1,RASL11B,MTMR9,SNAI3-AS1,CAMK2G,LDB2,CERS5,P2RX6,RAB33A,TPP1,ABCG1,MYADM,PITPNC1,ELMSAN1,FRY,ASB3,BSCL2,RASL12,INPP5K,GRK4,GABARAPL2,JAK1,KLRC3,L1CAM,MDM4,ETFRF1,PCSK1,PDE1C,ANKRD16,SKOR1,PRKCB,SLC25A36,RNASEL,KIAA0895L,ST6GALNAC6,SGK1,CHD9,TET1,KIF21B,TCF7,DDHD1,KCTD2,SSBP2,FAM155A,NAV3,RNF170" Coexpression M3936 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 1 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SYN3,ADORA2A,APAF1,BCL2L2,FOXK1,MTMR7,LARGE1,CLOCK,ARMCX2,WDR20,CPEB2,DTNB,EFNA3,EIF1,KCNMB2,RCSD1,RFFL,GSTM5,IL12A,KCNJ11,KLC1,TTYH2,CD200,TMEM38A,BAALC,RTN1,RYR1,KBTBD4,SLC15A2,SLN,SMARCD3,SNCB,SOX2,SOX15,KDM4C,SAMSN1,LRRC4,ADHFE1,PHLDB1,FBXW11,CLASP1,PUM2,PRRT1,NPL,UBC,NPDC1,EMSY,ZDHHC20" Coexpression M6415 Genes up-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACADM,ACTN1,NDRG2,BEND6,USP28,ASGR1,ZBTB10,TMEM108,ATP1B3,RNF182,LDLRAD4,USP2,ABCG2,SLC25A27,CSNK1E,SPOCK2,LYPD1,EIF1,EXTL2,ZIC4,PPP1R1B,SARAF,GGT7,GLUL,RAPGEF4,GUCY1A1,RASSF8,HNRNPK,PIK3CD,SLC36A4,SKOR1,FITM2,PRODH,PTK2,SUSD4,TMLHE,MCMBP,SATB1,BTBD7,ATF7IP,STX1A,FAM168A,PJA1,KIAA0930,WASHC4,TSC1,FRMD6,SENP7" Coexpression M7850 Genes down-regulated in T conv cells: IL35 treated versus untreated. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACTN1,PNMA8B,LRFN2,HACE1,CDK13,ASTN1,FUBP1,CAMK2D,FBXO7,NRG2,CSF1,IPCEF1,PPP6R2,ALKBH8,POM121,RABGAP1L,RCAN1,HIPK3,FGF13,TACC2,C1QL1,TCERG1,PRUNE2,GRM8,ADAMTS6,HNRNPK,CPT1C,USP54,P2RY1,PCMT1,PIK3CD,PRPH,ZSCAN2,PBRM1,WLS,HSPA4L,SGK1,LGI3,USP33,DDN,TCF4,TRIM2,FAM189A1,SIRT1,PRMT8,TRH,TRO,SSBP2" Coexpression M9133 Genes down-regulated in T reg: GATA1 [GeneID=2623] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ABHD6,ADD3,MAP4K3,NCOA1,STX16,DOCK11,SCAPER,MAP7,ZMYM4,KMT2C,AKAP12,GPSM1,TBC1D5,MED12,PHC2,PLXNC1,IRAK4,TLR7,ANKFY1,MALT1,KDM2B,ATE1,BACH2,IL6R,DIPK1A,JAK1,MEF2C,CD200,SESN3,NCF2,PFKFB4,SNX10,RETREG1,PLEC,SPATA6,CYBC1,ZNF493,BEND5,RUFY2,EPC1,SP4,SPTAN1,PRRC2C,FAM208A,KIAA1107,ZEB1,SYNE1,ZSCAN26" Coexpression M7329 Genes up-regulated in HMC-1 (mast leukemia) cells: untreated versus incubated with the peptide ALL1 followed by treatment with Cl-IB-MECA [PubChem=3035850]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SLC12A5,SRPX,KCNT1,LRCH2,LRRC4C,VXN,RHBDL1,ARHGEF25,ENTPD2,KMT2C,IGLON5,NRG2,C1QL2,GREB1,SPOCK2,ARMCX4,NSG2,DLL3,MSANTD4,FYN,MCHR1,DIDO1,IL11RA,ITGAV,MBP,MEST,HS6ST3,KCNK10,PENK,SDK2,PRPSAP2,PSD,VPS13C,PTAFR,ZIK1,REV3L,CCDC82,C12orf49,ZC3H14,RIMKLA,EMID1,ZNF354C,SORCS3,TMEM150C,ADGRL3,TUB,RGS7BP,FAM13C" Coexpression M9163 Genes down-regulated in CD4 T conv over-expressing XBP1 [GeneID=7494] versus XBP1 and FOX3P [GeneID=7494;50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACTN1,ADCY6,TMCC3,INTS2,ARHGAP20,RASL11B,ALDH7A1,FMNL3,ZMYM4,ZBED5,ABCG2,HOMER3,MAGED1,GPSM1,CTIF,ARMCX2,NYAP1,ARMCX1,CEP78,UBE2E3,B4GALNT1,KIAA1841,KDM2B,GSN,BACH2,NIM1K,JAK2,KIFC3,KIT,NRGN,CDIP1,SPATA6,WBP1L,PEX5,RGS12,GSTCD,ATXN2,TNFRSF19,ZFP30,CCDC88A,TET1,POGZ,GANAB,ARHGEF9,TCF7,TTC3,INTS3,NETO2" Coexpression M6839 Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naïve versus day 28 after immunization. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ABAT,ACADM,OGT,ATP1A1,MTMR3,MTMR7,ARHGAP33,CSF1R,SOCS5,DOCK4,DNAJC6,RCAN1,ENO2,EPB41L2,RRAGB,SEC23B,TMEM8B,GRB10,KAT7,RBPJ,KCNA1,VWA5A,MITF,TAGLN3,MYH6,NOVA1,PIK3C2A,PLCL1,POLG,MED1,TCP11L1,RYR3,SATB1,SNCA,GLT8D1,TROVE2,CAMTA2,TTBK2,PHLDB1,FAM168A,SUPT5H,PLCB1,CBX5,TTTY15,CLIP2,CLDND1,SNX27,EPM2A" Coexpression M3212 Genes down-regulated in comparison of immature NK cells versus intermediate mature NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACADM,NDRG3,AP2A1,CARNS1,ANXA7,PHYHD1,PLAA,DCAF8,TM9SF4,IP6K1,FBXL5,MAGI2,DPYSL2,ABI1,ABCC5,CERCAM,EPB41,RASGRP2,STX2,EZH1,AP4B1,SEPT9,GP1BB,KLF12,DIPK1A,KLC1,MARK1,OLR1,PFKP,PPP2R5C,PRKCB,PTPRE,PEX5,DCUN1D2,KANSL3,ELMO2,ZKSCAN3,KIF21B,ZC4H2,GANAB,GSE1,ZFP90,SIRT1,METTL3,EIF4ENIF1,UBE3A,AMZ1,ZSCAN26" Coexpression M3796 Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACTN2,KCNAB2,MARK4,MPDZ,BLM,CCKBR,CDO1,CHRNB2,HECTD1,LETMD1,FEZ2,DCT,CPEB2,ATN1,ANKRD46,GOLGA7,MRPL37,FCGR1A,CELF1,NSG1,GAA,NEK6,GLUL,GRIA2,GRIK5,HNRNPK,JAK1,KCNN1,ARHGAP12,MBP,GIT1,MRPL42,MXI1,NUCB2,ANLN,RETREG2,KCNIP3,CASC3,KIF21A,KIF13A,DOK5,CLUAP1,APOM,CNTN2,ACSL6,ITGB3BP,EVI5,IFT88" Coexpression M5434 Genes up-regulated in comparison of mast cells versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ABHD6,NR0B1,PKP4,ARRB1,CACNA2D2,CLTC,AKAP12,OSBPL3,IPCEF1,DAPK1,CNIH3,RHOBTB1,SV2A,RCAN1,EXTL2,TAOK3,ST3GAL6,FOXO3,SORBS1,FYN,ATP8A2,GLUL,ADGRA3,GRB10,GSN,HNMT,HP,SLCO1C1,TREM2,OLA1,PIK3R1,SMIM7,LRP12,RGS10,FRMPD1,SMARCD3,SPP1,ITPRID2,SST,ELOVL4,STX1A,ZFR2,CAMSAP2,SIN3B,TP53BP2,SLC30A4,ST7,RNF146" Coexpression M6079 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL4 [GeneID=3565] (2h). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "FGD2,PLA2G4C,ATP1A3,SYNJ2,CACNB4,HIP1R,CCKBR,ZBED5,TPP1,AKAP12,IST1,GIT2,CELSR3,EBI3,ELAVL4,EPB41L1,STX2,EXTL1,KAT8,FHL1,HPCAL4,TACC2,HVCN1,GAD1,CPLX1,STARD3,GRIK5,KCNH1,LIFR,NUMA1,ZNF827,PRKACB,SNRK,PTPN13,RFX5,PRR5L,RXRA,FOXRED2,FAM19A1,ASAP3,CLUAP1,INKA2,ATMIN,PCDHB15,SIK3,STXBP4,MEIS3,CPNE4" Coexpression M4331 Genes down-regulated in comparison of Homeo Convert versus Homeo Foxp3- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "PKP4,VAT1L,TNRC6C,ARHGAP5,NCOA1,DPY19L3,KSR1,CDK5R1,MAP4K4,CRMP1,LRIG1,CX3CR1,HDAC4,TBC1D5,RCAN1,CHST15,NSG2,STAU2,GPD2,GPM6B,RASSF8,TOX2,SMAP1,INPP5B,JAK2,HECTD2,STK32C,NTRK3,P2RX7,PDE3B,ENPP2,LRP12,FAM120C,RGS3,RNF220,RYR1,SEMA6D,SCG5,FAM102A,CHD9,FNBP1,CAMTA2,SEMA4A,TCF7,SYNE1,TGFBR3,MICU3,AMZ1" Coexpression M4311 Genes up-regulated in comparison of TregCD103-Klrg1 versus TconvLP (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "AS3MT,NCKAP5,ALK,ANK3,ARHGDIG,DCAF5,LRBA,ZBED5,ZFYVE9,TMEM59L,HAPLN1,SOCS5,ARMCX4,JAKMIP2,RHOBTB1,DMD,EGR3,ENO2,NRN1,SLC9B2,AMOTL2,TMEM107,PCDH11X,KIAA1958,LOXL3,GPT2,ADAMTS6,FRMD5,ZDHHC15,ITGAV,MATN2,PPM1L,ZNF862,NKX2-2,NUCB2,OXTR,PFKFB2,RETREG1,PYGM,SUSD4,GTDC1,BAALC,NCBP3,IL17RB,SH3GL3,C3orf70,VAV2,NLRP3" Coexpression M6306 Genes up-regulated in control macrophages: untreated versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SLC25A25,NDRG3,BRAP,PLEKHH1,AP2A2,OSBPL1A,AP1M1,DDR1,SYT6,CLU,C8orf37,DMTN,RASGRP2,F5,FGF12,FOXF2,USP21,ST6GALNAC3,GABRB3,LYVE1,PADI2,HSF2,IDH3A,IL12A,CHIC1,MEF2C,MKLN1,AFF1,MTR,NNAT,PDE1C,PKN2,MAPK9,MTMR10,ELOVL2,SPDL1,PTPRN2,ATXN1,SELL,FHOD3,ST8SIA1,SLA,SRPK2,SMOC1,POPDC3,PITPNB,MTCH1,JPH3" Coexpression M6983 Genes down-regulated in macrophages in response to LPS: naïve versus tolerant. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "RNF150,DYNLL1,LDLRAD4,CD86,LRBA,CHGA,IPCEF1,HDAC9,SMG7,KBTBD11,SEMA3D,MBNL2,SLC43A2,VPS26C,RCSD1,TLR7,ACSL4,PRMT5,BAIAP2,CHL1,STARD3,MFSD2A,LRRC75A,IRF8,IL12A,MIA2,POC1B,PRTG,PURG,PPP3CC,CYBC1,SNRK,TTC13,ATP8B4,DOCK10,SHMT2,CABCOCO1,SAMSN1,EPB41L3,DNAJC9,WASHC4,AKNA,PIK3R5,TRIO,TRPS1,WIPF1,EVI5,FRMD6" Coexpression M5154 Genes up-regulated in comparison of dendritic cells (DC) versus DCs exposed to M.tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ADORA3,GAS7,FAM131A,APOC1,CDK10,ASTN1,ADAM15,CALB2,CCNH,FOXN3,CHN2,LY86,HOMER3,SDC3,DCAF8,GIT2,POM121,SGSM2,ABCC5,SUGP2,ATP8A1,FOXO3,FOLH1,DCTN2,SYT17,SEPT9,STARD3,LILRA2,ACOT7,IDH3A,INPP1,ITPKB,MAN2A2,NACA,PLCB2,MAPK9,RNH1,SARS,ATXN2,SH3BGR,SMARCE1,SPTAN1,CAMTA2,WDR7,ZNF384,TRIO,SPHK2,UPF3A" Coexpression M7490 Genes up-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "EMILIN3,MTUS1,BCAR3,PI16,CDK5R1,CA12,CD86,MS4A7,RAB3C,LY86,CCDC151,CNN3,CSF1R,ATRNL1,PLCH2,CTNND2,CYBB,DCT,DUSP9,EGFR,RASA4,SLC43A2,IGSF6,TLR7,OLFM1,B4GALNT1,IRF8,ZNF385B,KCNQ3,KIFC3,PIK3AP1,TM6SF1,DIRAS2,ATP8B4,SGSM1,DGLUCY,SATB1,SELL,SPTAN1,NPAS3,TCF4,KIAA0930,TRPS1,LRTM2,ZIC1,KCNT2,SIGLEC10,PLD4" Coexpression M3469 Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus thymic stromal cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "C3orf14,BCL2L2,LDB2,CDH2,LARGE1,MAGI1,TMEM184B,CNN3,TENM4,FEZ2,CHD5,DNAJC6,MYEF2,CEP170,SACS,NTM,DYNC1I1,MAMLD1,SIDT2,CHST15,FGF13,SEC23B,TRIM16,ZMYND11,KCNK1,LAMP2,MEST,MYO5A,NEK1,DDR2,FAM216A,FTO,SMIM7,PKN2,CNTLN,UEVLD,BAALC,RXRA,ATXN1,HSPA4L,PREX2,SLC22A4,ZCCHC24,BEX1,CAMSAP2,TRIM2,DNAJC12,FZD3" Coexpression M5786 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 1 month later. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SLC12A5,OSBPL1A,SEMA6A,BMPR1B,DST,SLC25A14,CCNT1,CBFA2T2,EPS15L1,COX4I1,CP,CLOCK,SLITRK5,ARMCX4,RHOBTB1,SUGP2,EIF5,ING4,C3orf18,RCAN2,RABEPK,PIPOX,SEMA6C,DCTN2,PRELID3A,GFER,GRIA1,GUCY1A1,GUCY1B1,HSPA1L,KCNMA1,KCNN3,SMAD1,NRCAM,PCSK2,PDPK1,CCSER2,TNPO2,TMEM104,TUG1,C1orf54,RPL15,ATAT1,ASRGL1,RUFY2,PBLD,TROVE2,TRIM2" Coexpression M5096 Genes down-regulated in comparison of naive CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "APBB2,DDX3Y,N4BP2L1,LDHD,BAIAP3,PTBP2,MAP7,USP2,DIS3L,FGFR1OP2,PLEKHM1,CEP170,WDR20,DLG2,DLX1,YAF2,KMT5B,ASB3,CERCAM,EVL,FYB1,ZMAT1,ZMYND11,DIDO1,SLC2A6,HMGCR,LSS,P2RX7,PPP3CC,PKN2,RDX,SCAF8,WDR47,NAPB,CPEB4,USP33,KLHL7,ATP11A,GPRIN3,AHCYL2,ACTR6,TPD52,KCNE5,TST,BCL2L13,CLIP2,ZFAND5,EMSY" Coexpression M9119 Genes up-regulated in CD4 T conv: control versus over-expression of IKZF2 and FOXP3 [GeneID=22807;50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ABHD6,FGD2,TNRC6C,MIER1,ARRB1,CAPRIN2,TMEM108,AP1M1,SPAG9,CD86,ZFP28,CNRIP1,AKAP12,GIT2,IRAK4,CALCRL,TLR7,EZH1,CHST15,SEC24B,ANKFY1,GLUL,DIPK1A,MBP,SSH1,ZNF655,PRKCB,C1orf54,ZNF493,SLC25A36,LRRK2,WLS,ZNF821,DHX30,SLC14A1,MTERF2,EPC1,INTS9,SP4,ARHGAP26,MPRIP,STX1A,KIAA1107,SZT2,TK2,TPM3,TRIO,RFTN2" Coexpression M4638 Genes down-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 7 versus untreated CD25- T cells at day 7. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ASGR1,ATP1B3,BACH1,ST3GAL5,MYRF,SLC25A14,CARS,SPAG9,CD86,PDE4DIP,KIAA0040,CTNND2,DOCK4,HDAC9,KIAA0513,DSCAM,SH3GLB1,EML1,F3,EFCAB2,ATP6V1H,AHCYL1,MTHFD2,GK,LILRA2,IL6R,JAK2,NCF2,SERPINI1,PSMA6,PTAFR,RGS3,RPS6KA2,SARS,SCG5,SHMT2,R3HDM2,MAST1,CAMSAP2,TBL1X,NACC2,ZMYND8,LAT2,TRIM9,SYNC,SLC30A3,NELFE,SSPN" Coexpression M5509 Genes down-regulated in comparison of macrophages versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "AGT,ANK3,CDK13,CACNA1G,THSD7A,SYNGR3,DGKI,RAB26,AKAP6,KIAA0586,DBT,PITPNC1,TIAM2,HP1BP3,LINC01278,GAB1,ATP8A2,LOXL3,GNG4,ADGRA3,HSF2,ITPKB,KCNA1,ZNF862,NAP1L2,NASP,ODF2,SNTG1,PCSK2,NLE1,PMP2,PPP3CC,PTPRD,ZDHHC4,STK32B,SMPD3,PKNOX2,IGSF9B,MYO16,UNC5B,NPAS3,SYNE2,SYT1,SYNE1,PCDHGA1,ZNF34,RUSC1,MARCH8" Coexpression M7954 Genes up-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565]: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "AS3MT,ADCY6,APP,ZFYVE28,CADM3,RGS11,LARGE1,CFL2,TRIM69,KIAA0040,RIMS3,EEF1A2,ELAVL2,TMEM35A,LRRC23,RPS6KC1,TBC1D16,TESK2,FGF13,CAP2,APOPT1,BRPF3,TUBA8,NIM1K,AQP11,SRSF12,NME4,PDE3B,PDE4B,PFKFB2,TMIE,C19orf57,RASGRF2,BEND5,C12orf49,ZFP2,ST8SIA1,KDM4B,CAND2,KLHL4,DNAH7,TPD52,TRIO,RUNDC3B,SSBP2,SGK3,SPHK2,LMAN2L" Coexpression M9624 Genes up-regulated in CD4 [GeneID=920] T helper cells Th0: control versus NaCl treatment. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACHE,C1QTNF1,PHF12,CASK,ALDH7A1,SEC11C,C5,CACNA1B,CANX,CCKBR,LRBA,TBRG4,COL9A3,COX4I1,PNKD,HINFP,TOMM20,EFNA2,ZIC4,GABRA3,GART,GNG3,PTPN5,FICD,IL12A,KCNA2,KCND2,KCNJ11,CHIC1,MMP17,MOV10,NEXMIF,NRCAM,PDGFRA,EPB41L4B,PKN2,DEF8,PTHLH,ZSCAN2,ZYG11B,NAPB,SLC22A4,TROVE2,ABCC8,BEX4,TRPC1,UBC,VLDLR" Coexpression M3217 Genes up-regulated in comparison of CD4 [GeneID=920] T cells activated with lamina propria dendritic cells versus regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "RNF150,BCAS1,CDK5R1,CCPG1,KIAA0040,RABGAP1L,FAM107B,HIPK3,FKTN,DOT1L,OGA,SESN1,SPIN1,TNRC6A,ZHX1,BACH2,ZDHHC15,SCIN,KIF5C,LIG4,AFF1,SESN3,BCO1,NFIX,PCSK1,ZNF655,PLCL1,PPM1B,MAPK8,BCAS3,ZNF493,REV3L,ERI2,ATXN7,LMBRD1,SP2,ERBIN,STX1A,ANKRD12,KAZN,ALG1,NSD1,ITGB3BP,SLC44A1,TPM3,BCL2L13,ITM2C,DOCK8" Coexpression M8088 Genes down-regulated in myeloid-derived suppressor cells: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "CLK4,KDM5D,ARID1A,ADRB2,ZNF608,DDX3Y,TMEM108,DOCK11,PROM1,CDK5R1,FOXK1,MAP7,CCNH,SLC16A4,SLC4A7,RBM39,AKAP12,DZIP3,TOX,LPAR6,PTK2B,ATP8A1,FYN,SESN1,EML4,RAPGEF4,BACH2,LMO2,GPR155,LDLRAD3,TM6SF1,CD200,DDX25,PDE4B,RETREG1,RFX5,RPRD1A,LRRK2,SELL,DOCK10,CCDC88A,FAM208A,TMPO,NR2C2,CADM1,CCDC14,RICTOR,VANGL2" Coexpression M8200 Genes up-regulated in double positive thymocytes: wildtype versus over-expressing HDAC7[GeneID=51564] fused with VP16. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ANXA7,B3GALT2,BCHE,ST3GAL5,BSN,ARHGEF25,CD86,COL9A1,PREPL,ENTPD4,CYBB,PITPNC1,CDON,E2F5,GPHN,FGF1,NSG2,TPPP3,GFRA2,STMN2,HAS2,PTGDR2,HTR5A,HES5,KCNJ3,ADAM22,NPTX1,CDK14,PTPN13,PTPRN2,RGR,RYR3,SCN3A,FNBP1,TAL1,TBCEL,TBX15,TNS2,ICAM5,TRPC1,HSPBP1,ZKSCAN5,PITPNB,ZFP37,MEIS3,CIAPIN1,CAB39L,AAAS" Coexpression M5945 Genes involved in metabolism of heme (a cofactor consisting of iron and porphyrin) and erythroblast differentiation. MSigDB H: Hallmark Gene Sets (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ADD1,ADD2,ALAD,ANK1,ATP6V0A1,BACH1,SYNJ1,BTRC,CAST,CDC27,CLCN3,FBXO7,ABCG2,GAPVD1,TMCC2,TSPAN5,SIDT2,OPTN,EPB41,DMTN,EZH1,FECH,FOXO3,ALDH1L1,CROCCP2,NR3C1,LAMP2,LMO2,MARK3,MXI1,SLC11A2,PC,SMOX,RAP1GAP,SLC30A10,SEC14L1,SLC6A8,SLC6A9,SLC22A4,SNCA,SPTB,TAL1,TCEA1,ACSL6,ARHGEF12,TNS1,OSBP2,MARCH8" Coexpression M4579 Genes up-regulated in comparison of adult DN2 thymocytes versus fetal DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ADCY6,OSBPL1A,ALCAM,NCOA1,RASL11B,BCL2L2,SYNJ2,BAIAP3,FEZ2,PITPNC1,CD99L2,CALCRL,PIPOX,FGF13,SARAF,TRAF3IP2,INPP5K,PARD3B,GSTM5,SOWAHA,IL6ST,SYTL4,MEF2C,MXI1,NEFH,PCBP3,SERPINE2,SERPINI1,GPSM2,SMOX,EPB41L4B,SYTL2,RPS6KA2,WLS,DGLUCY,SELL,ST6GAL1,SLC14A1,ABTB1,SSTR2,ARC,SLC37A2,DDHD2,TCF7L2,SYNE1,UCHL1,SLC30A4,FRMD6" Coexpression M5128 Genes down-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "MRTFA,OGT,APP,BTK,DDR1,CH25H,ARHGEF1,ZMYM4,PPT2,QKI,HOMER3,MYADM,SIRPA,DPYSL2,PLEKHA1,SRRM1,FDFT1,SEMA4D,SMC2,USP21,B4GALNT1,TCERG1,HMGCR,ITGA7,PAXBP1,MAT2A,MOV10,SFR1,OGG1,ABCB1,PRKACB,PRKCB,RELN,CYBC1,PBRM1,RPL15,RTN1,FCHO1,KLHL7,SYPL1,TAF6,PUM2,ARHGAP9,LRRC8A,TPM3,C9orf85,USP1,WNK1" Coexpression M3605 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SLC25A25,ADORA1,ADRB2,MAP4K3,APC,APP,TMEFF1,SEC11C,CCK,CCKBR,USP2,MYOM2,CLTB,AKAP7,CRY2,ABCG1,DLX1,NR1D2,E2F5,EEF1A2,ERCC2,TLR7,F3,FABP7,UBE2E3,USP21,NEURL4,CNTRL,PRDM5,IDH3A,INSM1,KITLG,MX1,MYH7,NFIX,PKD1,RETREG2,PRPSAP2,RASGRF2,BSDC1,RPS6KA2,GALNT10,SLC6A8,ST5,MAPK8IP3,JMJD6,AMACR,ST7" Coexpression M7859 Genes down-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with IL-23. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SLC25A25,OSBPL8,TXNDC16,TAOK1,LCORL,ZBTB10,ATP2B1,BACH1,DCAF5,SRSF11,ZBED5,DNAJB5,AHCTF1,NR1D2,TOM1,SIDT2,EPB41L2,DENND4A,CAMSAP1,MPP6,FYN,IRF8,MAT2A,LDLRAD3,AFF1,CNOT4,ZNF655,RETREG1,MINDY2,MAPK8,RBBP8,MSANTD2,REV3L,GTDC1,ACER3,SATB1,ATXN2,DOCK10,EPC1,RBM34,BDP1,SPP1,TBCEL,TCF12,TF,TPD52,DHX33,SSPN" Coexpression M6208 Genes down-regulated in polymorphonuclear leukocytes 9h after infection by: S. aureus versus A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "RNF157,DPY19L3,BAIAP3,USP2,PICK1,SLC25A27,ARHGAP24,INTS1,C2CD2L,DDX46,SIDT2,SUGP2,KATNAL1,TESK2,ZNF512,GABBR1,B4GALNT1,CRCP,STON1,ZNF496,CIT,DHX35,KCNH2,MAPK7,BCAS3,GON4L,PXK,RAB5B,RGS12,SCN2B,IL17RB,SLC20A2,ARFGAP1,ERC1,DNMBP,ATMIN,SZT2,VWCE,ZMAT3,TIAM1,ZNF384,ZNF346,SLC35A4,MICAL1,WRN,ZNF142,PARP11,VANGL2" Coexpression M6437 Genes up-regulated in CD8A [GeneID=925] T cells versus B2 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "CARNS1,KCNT1,ZFAT,APOC1,ATP1A1,ADAM23,SCARB1,DGKI,TAOK2,ATRNL1,MYADM,KIAA0513,RIMS3,DGKG,ZNF804A,ACOT8,FIS1,SIDT2,RASGRP2,RTN3,EXTL1,PRAM1,B4GALNT1,GPD1,HP,IL6R,KCNJ9,GATD1,KHK,L1CAM,LIFR,NAT8L,MBD1,MYL3,HNRNPM,P2RY13,ENPP2,MRAS,NTNG1,ELMO2,ZKSCAN3,SON,SPTB,EPB41L3,CYB561A3,LRTM2,SIGLEC10,TTC7A" Coexpression M3224 Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "DSCAML1,SNX30,ZNF608,ARHGAP5,MYOM1,MTMR3,IL33,CAMK2D,SLC4A7,FAM107B,DYNC1I1,DRD1,DUSP9,ZIC4,FGF12,NBEA,GBX2,SESN1,PRDM5,MAP4K5,BACH2,DOCK7,IL6ST,ZNF385B,PPM1L,NEFM,NFIX,PCBP3,NUCB2,MAGEL2,PPP1R1A,SKOR1,RELN,TMEM100,DRAXIN,SMPD3,SGK1,SLC14A1,ZCCHC24,LARP4,ZSCAN29,ASTN2,AHCYL2,DNAH7,THBS4,PARD3,RPRM,ITM2C" Coexpression M9792 Genes up-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SYS1,UNC5A,BEND6,TRMT9B,APBB1,CFLAR,BMP7,METTL6,CD38,CFL2,COG1,RASGRP1,ERBB2,MRPL10,FCGR1A,SUCO,AGAP2,FYB1,FAXC,GPD2,GPM6A,FICD,HRH3,HP,FGFBP3,LSAMP,CHIC1,MSR1,MX1,IDNK,NINJ2,NPPA,ETFRF1,PGAM2,PLP1,RALGDS,ATG16L1,DPF2,MAP6D1,COPZ1,RGL1,PCDHB15,CYB561A3,TMEFF2,HIRA,UBC,SPHK2,NLRP3" Coexpression M8255 Genes up-regulated in B lymphocytes with NFATC1 [GeneID=4772] knockout stimulated by anti-IgM: 3h versus 16h. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "PLEKHG5,OSBPL8,APOC2,PDXK,ARRB2,ATP2A2,MPDZ,RAB29,B4GALT6,ARHGAP22,TMEM59L,CNR1,GDA,ATL1,PLXNC1,FGFR1,UBE2E3,CAP2,FOXO3,RASL10A,SRCAP,GLUL,GRM5,HSP90AA1,ITGAV,MATN2,MEF2C,FXYD6,NCAM1,CNTN3,PDE2A,PFKFB4,TUG1,PID1,ERI2,RPRD1A,RASA3,ST6GAL1,SLC12A2,SPART,FGD4,C3orf70,TCF4,SLC44A1,LRRC8A,KCTD2,ZNF384,SF1" Coexpression M9555 Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=3398] knockout versus ID2 and BCL2L11 [GeneID=3398;10018] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ALCAM,ALS2,BCHE,HCN2,BTK,CANX,DCAF4,DNM1,DSCAM,EEF1A2,PLXNC1,SPECC1,SDCBP2,GABRA2,GALR1,ATP8A2,TUBA8,ZNF276,MSL3,GP1BB,GUCY1A1,KCND1,SMAD1,MID1,MPP2,MSRA,TAGLN3,NDP,HCN1,NTRK2,PLCD1,PMP22,NXPH1,PPP3CC,RGR,MYH14,RYR3,DGLUCY,SOX6,SLC8A3,SOX3,UNC5B,ST5,SEMA4A,AHCYL2,TPM2,PCDH20,SLC4A10" Coexpression M8630 "Genes up-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]." MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "PDXK,PRMT9,REPS2,SOCS6,CNRIP1,PREPL,ABCG1,SDC3,ARHGAP24,KIAA0513,G3BP2,NR1D2,LPAR6,TESK2,FGF13,DENND2A,GATM,GPT2,KIF3A,GYG1,ARHGAP19,HMX1,IGF1,IL11RA,METTL21A,STXBP5,GPR155,TM6SF1,MXI1,RTL5,SLC36A4,MINDY2,TATDN3,MAPK9,SLC26A11,QDPR,RAB3IL1,CPEB3,ST6GAL1,RCOR3,TROVE2,KIAA0930,WDR7,HEY1,PDSS1,AMACR,ZBTB16,FAM219B" Coexpression M4559 Genes up-regulated in comparison of adult thymic progenitors versus adult DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SPOP,FGD2,N4BP2L1,CD86,CD81,B4GALT6,CSF1R,CTNND2,MYADM,YTHDC1,EBI3,PLXNC1,TLR7,SPECC1,NEK6,IQGAP2,ATP8A2,GCNT2,PRDM5,MAP4K5,IRF8,DOCK7,LMO2,MEF2C,MEIS1,SESN3,MYCN,NUCB2,RETREG1,PPP3CA,PTPRE,SLC25A36,ROBO1,DGLUCY,PEAR1,ITSN1,FHOD3,ST6GAL1,DZIP1,DDHD2,TAL1,TCF7L2,ZMAT3,TRIO,TTPA,ZBTB14,PARP6,GDPD5" Coexpression M8490 Genes down-regulated in B16 melanoma during adoptive transfer therapy: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "CSMD3,KCNT1,LRFN1,DPP10,ANK1,FGD2,PPFIA4,ARRB2,SCAPER,ARHGEF25,EVI5L,IGDCC3,C1QL2,DCC,SGSM2,DNM2,CERCAM,ELN,TMEM74,STAU2,FYN,GABRG2,GGT5,GPR45,ACOT7,NKD1,LIX1,KCNJ9,HECTD2,STK32C,MT3,OMG,OXTR,PRTG,FXYD1,PRKCB,ZDHHC14,TMEM150C,TEX15,ZFPM2,CRB1,FNDC5,KCNE5,ZFP37,SLC30A4,MDH1B,PPP1R3F,FBXO36" Coexpression M3531 Genes up-regulated in comparison of activated CD8 T cells from ELF4 [GeneID=2000] defficient mice versus those from wild type animals. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "FAM135A,GPRASP2,CDC14B,TMEM263,DPY19L3,SCAPER,CCNH,MYOM2,AP4M1,ASIC3,CLU,AKAP7,BAG4,LRIG1,CTH,ARHGEF4,DLG3,YAF2,KCTD3,ARMCX1,CINP,FAM49B,ARFIP1,RBPJ,SLC35G1,GATD1,KIF2A,KIF5C,NCOA7,NNAT,KCNK10,ENPP2,MAPK9,CEP97,ERI2,RPRD1A,NUBPL,BTBD7,ELOVL4,DIP2A,BHLHB9,C9orf85,TRPC1,RPL7L1,GORASP1,RNF103,KLHDC1,SENP7" Coexpression M6067 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus untreated (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "NDRG3,KIAA1324,ALAD,AMPD3,AMT,APBA2,SCAPER,CACNA2D2,TPP1,NMT2,WHRN,LETMD1,ATRNL1,DCAF8,RASSF2,SPOCK2,CHRDL1,DTNB,SIDT2,BSCL2,ZNF589,FOXO3,EVL,NBEA,POMT1,SEPT9,ATP8A2,PRRC2B,IL11RA,ZNF862,OPHN1,PLCB2,GRAMD1C,RGS10,RNASEL,ZNF671,RPS20,ZFP30,FAM102A,ZNF334,COLGALT2,NACAD,GSE1,MLC1,CUX2,TCF7,PRMT8,ITM2C" Coexpression M6987 Genes down-regulated in naïve untreated macrophages versus tolerant macrophages stimulated by LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "ACLY,RBM10,AP2A2,TMEM108,CNN3,IPCEF1,GPSM1,HDAC9,KBTBD11,ABI2,PAN3,DCTN4,SRRM1,TBC1D16,CHST15,IP6K2,TRAF3IP2,TNRC6A,PTGDR2,IRF8,MSL1,PIK3AP1,MN1,HCN1,NUCB2,SETD4,OPA1,PDE2A,PDE3B,PLCL1,EPB41L4B,MED1,PRKCB,UHRF1BP1,ATP8B4,SATB1,ATXN2,LGI3,TET1,CDK19,TCF4,AKNA,CYB561A3,TIAM1,UPF3A,DHX33,SLC38A1,CERS6" Coexpression M8864 Genes down-regulated in lymphoid primed multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "CDC42BPA,ANK2,ADGRB1,CA12,ZBED1,CDH10,CLGN,CHGB,ARHGAP22,NRXN2,HOMER3,MAGED1,CRMP1,CRYBB1,PHC2,ERBB4,TRMO,CAMKK2,GAB1,GABRB3,PCDH17,TXNL4A,RAB30,LILRB4,GPR17,PCLO,GRIK5,GRM8,PTPRT,IL1RAPL1,HSD17B1,MEIS1,MYBPC1,NINJ2,NKX2-2,PCSK5,PLPPR1,PTPRZ1,SALL1,SCNN1D,TRA2B,SYT5,EHBP1,ACSL6,TEX15,TIE1,FAM155A,ZNF142" Coexpression M5069 Genes up-regulated in comparison of CD4+ [GeneID=920] CD8- thymocytes versus CD4- [GeneID=920] CD8+ thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "PWWP2A,AP1B1,TXNDC16,SFMBT2,ARHGAP5,GPR146,CAST,CD81,FOXN3,CLCN4,ARHGEF6,AKAP12,ARHGEF10,MAML1,DNAJC6,HP1BP3,DLG3,RASGRP1,KMT5B,TMEM35A,PAN3,CAMKK2,ZMAT1,IL6R,TNPO2,PPM1B,WBP1L,SYTL2,RAB5B,IL17RB,GALNT10,SH3BP2,ST6GAL1,PPP4R3A,TET1,CPEB4,RCOR3,ERC1,CAMTA2,NEK4,TBL1X,WASHC4,ZMAT3,ZFP91,TSC1,LRP8,UBE3B,JMJD1C" Coexpression M5507 Genes down-regulated in comparison of macrophages versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "SPOP,SLC2A11,N4BP2L1,ARHGEF7,SLC25A14,CBLN1,ARHGAP33,LOC730101,AKAP7,IFFO1,ZNF337,HEYL,TNK2,OLIG2,TESK2,EVL,USP21,FYN,GABRA3,RAPGEF6,CROCCP2,BTN2A1,HSPA1L,IL11RA,KCNN3,LSAMP,MYBPC1,MYH3,DPY19L2P2,PCDH8,PDE4B,POLG,PTCH1,FAM120C,TUG1,ZCWPW1,SAFB,GALNT10,CDK5RAP3,SORCS3,TSPYL2,POGZ,MAPK8IP3,MMS19,TRPC1,MPPE1,MVB12B,KAT6A" Coexpression M5393 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 48 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "PPFIA2,ALDH4A1,OSGIN2,CDC42,FHL5,CREB5,IPCEF1,RASSF2,DAPK3,POM121,DYNC1I1,SRPK3,RASGRP2,FABP7,FCGR1B,TESK2,OLFM1,AFF2,B4GALNT1,WASF3,LILRA2,ADAP1,PACSIN2,HLF,KCNJ9,PACRG,KCTD15,PLXNB3,TRHDE,PILRA,SYTL2,PTPRE,ZMAT4,LRRTM4,SLC22A4,SLN,WDTC1,SST,SSTR2,JMJD6,PCDHA5,GPR161,AKTIP,MTMR14,TLL2,TLR4,UBE2H,DPF3" Coexpression M7916 Genes down-regulated in macrophages (6h): IL4 [GeneID=3565] versus IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "DPP10,PHYHD1,INSYN2B,ATP2B3,KALRN,PRC1,LARGE1,KIAA1549L,FEZ1,LRRC3B,CTNND2,KIF26A,BRINP1,B3GAT3,C3orf18,FOXO3,POMT1,GAB1,GABRB3,CSDC2,PSRC1,GPR34,GRIA2,NR3C1,OLFM3,KCNN2,SYT9,MMP16,MN1,OPCML,NALCN,MBD5,SON,SPATA7,NMNAT2,MYCBP2,ATP10B,THSD1,MLC1,ABCC8,PLCB1,SYT4,TAC1,CUX2,CFAP52,TCEAL7,FBXO36,SENP7" Coexpression M5122 Genes up-regulated in comparison of CD4 [GeneID=920] dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "TKTL1,ACTN2,ANK3,APLP1,PTCH2,CDO1,CFL2,CHRM4,TPP1,CTNND2,FBXL5,DYNC1I1,NR1D2,FEM1B,TENM1,ERBB4,FER,AFF2,GALC,GAP43,PPARGC1A,IDH3B,ITGAV,MATN2,MGAT3,COMMD5,NEUROD2,NPTX1,PDCD2,RETREG2,POLG,PKN2,PTAFR,PTPRB,EML5,ZYG11B,RLBP1,DCUN1D2,SMTN,SNCA,KLHL7,TAF9,WWC1,TCF12,ICAM5,DDHD1,R3HDM1,DPF3" Coexpression M4561 Genes up-regulated in comparison of adult thymic progenitors versus adult DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 48 200 "OSBPL1A,SPOP,FGD2,APBB2,ST3GAL5,CD81,B4GALT6,LY86,CSF1R,MYADM,PITPNC1,FAM107B,EBI3,IRAK4,SPECC1,GAB1,NEK6,DNER,GATM,GGT5,GPM6B,PRDM5,MAP4K5,IRF8,ITGAV,LMO2,MEIS1,GON4L,PTPRE,ROBO1,DGLUCY,ZNF821,ITSN1,FAM102A,FHOD3,ST6GAL1,LHPP,EPB41L3,CEP68,DDHD2,TAL1,AKNA,TP53BP1,SEZ6L,TRIO,TSC1,MICAL1,GDPD5" Coexpression M4001 "Genes down-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.07E-03 1.00E+00 1.03E-02 1.02E-01 21 68 "ADORA1,SPARCL1,PPFIA4,ARHGEF6,MICAL2,SPOCK2,EDN3,EDNRA,MSTN,KCNH2,NEFM,PDE4D,LRRN3,PKIA,RADX,TNIK,SOX11,COBL,TCF4,WDR7,REEP1" Coexpression 19305503-TableS1 Rat Brain_Greco09_425genes GeneSigDB 1.08E-03 1.00E+00 1.03E-02 1.03E-01 83 387 "ABAT,ACTN1,GALNT16,ADD3,ADGRF5,SPARCL1,BBOX1,ATP1A2,MTMR9,ADAM15,BCS1L,PROM1,BMP7,C1QC,CALB2,CBS,USP2,RGN,P2RX6,CDO1,DLGAP1,CHN2,RAB28,TPP1,VCAN,DBT,HS3ST2,F3,CACNG3,FHL1,SYT3,DKK3,SEPT9,CPLX1,FERMT2,GPM6B,GPR37,FAM107A,GYG1,PACSIN2,SCRG1,HPCA,HES5,KCNK2,KCNN2,KIT,ZFYVE27,NEFM,SLCO1C1,NFE2L2,NPTX1,NUCB1,GPR88,PC,PDE4B,PDGFRA,PSAT1,SPATA6,PRPH,PTPN13,UBR7,KCNIP2,SUPT20H,SGK1,CNKSR2,SLC6A1,SLC9A5,SLC15A2,PDZRN3,SST,SSTR1,SSTR2,TAC1,TACR1,TIE1,RASD2,TPM1,SLC35A4,ITM2C,SLC17A6,NELFE,CAMK1G,CBLN2" Coexpression 15326474-Table2a Human Stomach_Subramanian04_49genes_KITexon11mutant GeneSigDB 1.08E-03 1.00E+00 1.03E-02 1.03E-01 14 38 "CCKBR,SNCAIP,GRIN3A,EFS,B3GAT1,CIT,GUCY1A1,SYTL4,MYCN,PTPRD,ROBO2,SH3BGR,FLRT2,GJC2" Coexpression 17724462-Table1 Human StemCell_Nuytten08_44genes GeneSigDB 1.08E-03 1.00E+00 1.03E-02 1.03E-01 14 38 "PCDH10,GPAM,YAF2,RPS6KC1,GRIA2,GRM8,COMMD5,RSPO2,NME4,MAPK7,DIRAS2,EPN2,DIP2A,NETO2" Coexpression M8009 Genes up-regulated in atria of failing hearts (DCM and ICM) compared to healthy controls. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.08E-03 1.00E+00 1.03E-02 1.03E-01 14 38 "ARID1A,ATP6V0A1,EFNA2,LINC00599,EPHA5,FGFR1,PFKFB3,PLEC,PPP5C,NCDN,APOM,TNNT1,LILRA4,TRIO" Coexpression M4706 Genes up-regulated in comparison of dendritic cells (DC) stimulated with R848 at 2 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h. MSigDB C7: Immunologic Signatures (v6.0) 1.09E-03 1.00E+00 1.04E-02 1.04E-01 47 195 "SNX32,GOLGA7B,AMPH,MYH7B,KIF1A,CACNG1,CLDN10,IGFN1,CLGN,TJP2,IQCK,PCYT1B,SLC35F1,HINFP,GABRG2,GLI2,GPR19,IGSF21,SHISA6,IGFBP1,KIT,SMAD1,AQP11,CHIC1,MGAT3,HS6ST3,PCDHGC3,POU3F2,PRKCZ,EML5,STRC,ROBO1,ZNF671,RTP5,MYT1L,ASTN2,PJA1,SMG6,TCF7L2,CCDC173,TJP1,LRTM2,ZKSCAN5,TUBB2A,ZIC1,ZNF708,ZNF23" Coexpression M2228 Genes down-regulated in erythroid progenitor cells from fetal livers of E13.5 embryos with KLF1 [GeneID=10661] knockout compared to those from the wild type embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.09E-03 1.00E+00 1.04E-02 1.04E-01 354 1972 "ABCF1,ACADM,ACLY,RBM10,ACTN1,ARID1A,ADD3,CDC7,SNX30,ESYT2,KIDINS220,ZNF608,MTUS1,AK2,SPOP,EP400,C6orf89,PARG,APAF1,KCNAB2,TNRC6C,API5,USP37,PDXK,ARNTL,ARRB2,EIF4G3,ATP1B3,STX16,MTMR9,RIPK1,DOCK11,BACH1,SEC11C,BCL7A,CFLAR,PROM1,SYNJ1,BTK,AP1M1,FOXK1,CALM1,CAMK2G,TRIM41,CANX,CAST,HIP1R,MAP7,PRC1,CERS5,CCNH,CDK11B,CDC42,LRRFIP1,COPB2,SRSF11,FOXN3,SOCS6,B4GALT6,KMT2C,RAB28,CLTA,QKI,LY86,CNN3,ARMC8,BTF3L4,SLC4A7,SMARCAL1,SH2B1,AKAP12,RNF14,ANKRD44,NCOR1,NCOR2,GDA,CSF1R,CSF2RA,CSF3R,CSNK1G3,ATRNL1,SIPA1L1,CST3,PNPLA8,PUM1,CYBB,FGFR1OP2,RIPOR2,MAML1,IST1,DBI,GIT2,PITPNC1,ELMSAN1,ZEB2,ZBTB24,ELMO1,HP1BP3,FBXL5,SMG7,G3BP2,RABGAP1L,FAM107B,DOCK2,DPYSL2,ABI1,PDCD6IP,DNAJB6,FARSB,TSPAN5,ANKRD46,HIPK3,FEM1B,FCF1,KLHL5,FRY,YAF2,EBI3,KMT5B,PLXNC1,LPAR6,IRAK4,CERCAM,USPL1,VPS13B,EPB41L2,GPHN,IGSF6,RCSD1,EXTL2,F5,TAOK3,FCGR1A,SEC24B,POLR1B,TMEM164,FGR,UBE2E3,PCYOX1,ANKFY1,NOP56,TMEM175,JKAMP,FAM49B,CAMKK2,CELF1,MSANTD4,MPP6,FYN,CAB39,B4GALNT1,ZNF274,IQGAP2,ERAP1,GART,CPLX2,TUBGCP4,SESN1,GGTA1P,BRD8,TXNL4A,TCERG1,RNPS1,DBF4,SPIN1,GLYR1,TNRC6A,MSL3,KDM2B,GPD2,ADAP1,CECR2,RFFL,NR3C1,CIT,GSN,GYG1,MUM1,NCKAP1L,ELOVL5,ACOT7,HMGB1,HNRNPK,HP,IRF8,MSL1,IDH3A,C5orf24,RBPJ,IL6R,INPP1,DIPK1A,INPP5B,ITGAM,ITGAV,KCNJ11,KIT,IPO5,STXBP5,LAMP2,STMN1,LMO2,MAN2A2,MARK3,MBD1,MBP,LDLRAD3,TM6SF1,MEF2C,AFF1,THYN1,MYO7A,HNRNPM,NAP1L1,NASP,NDUFA5,SFR1,NFYA,PCMT1,PDE2A,PDE3B,PDPK1,GNG2,FAM98B,ANLN,PIK3CD,PIK3R1,RC3H2,PSAT1,ING3,SH3KBP1,MED1,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PPP5C,PRKCB,MAPK8,FITM2,PXK,PTPRE,TTC13,TUG1,PPP2R3C,QDPR,C1orf54,RAP1GDS1,ROGDI,OXR1,RDX,ERI2,RFX5,UBR7,RPRD1A,DCUN1D2,SETD5,ATP8B4,ACER3,RPS6KA2,CLIP1,NCBP3,SAFB,SCP2,SELL,SUPT20H,TRA2B,SCAF8,DOCK10,FBXO11,SEC31A,SLA,DHX30,RAB3GAP1,BTBD7,ATF7IP,EPC1,NAXD,SMARCE1,TTC17,TMCC1,SON,FNBP1,UHRF1BP1L,MYCBP2,TEX2,CDK19,ZBTB43,RAP1GAP2,SRPK2,TAB2,POGZ,SS18,SULF2,FAM168A,KLHL7,PRRC2C,SYPL1,ANKRD28,ATP11A,TACC1,SEMA4A,TAF9,AGTPBP1,FBXW11,TBL1X,SIN3B,CLASP1,SYNE1,AKNA,PUM2,ARHGAP9,SIK3,CYB561A3,ATP13A2,DICER1,SIRT1,ZNF106,TIAM1,ACTR6,BHLHB9,TMPO,KCTD2,TP53BP1,TP53BP2,TPM3,C9orf85,TPM4,NR2C2,ZMYND8,SGK3,EIF4ENIF1,PITPNB,USP1,VAV1,WIPF1,CLDND1,XPO1,ZBTB14,ZBTB16,DHX33,INTS3,WNK1,SLC38A1,CAB39L,MPPE1,C12orf4,DOCK8,KAT6A,HNRNPA3,CERS6,RSPRY1,ZDHHC20,RNF146" Coexpression 18172295-SuppTable2 Human Bone_Heller08_324genes GeneSigDB 1.10E-03 1.00E+00 1.04E-02 1.04E-01 60 263 "ABAT,APLP1,SHTN1,CDK10,TMEFF1,ALDH4A1,ADAM15,CACNA1G,WASF1,BAIAP3,SPAG9,CLTC,SLC4A8,AKAP12,PDE4DIP,DAPK3,DBN1,DNM2,SEZ6L2,AASS,CDKL3,TAOK3,FER,KIAA1109,FHL1,SORBS1,CGREF1,CYP46A1,STARD3,PCSK1N,GPM6A,GSN,HBA1,MAN1B1,ITGA7,KHK,L1CAM,MEF2C,NCAM1,NRGN,ENPP2,SERPINI1,PIK3CD,GPSM2,PRPH,NUDT11,SBF1,SH3GL3,PPM1E,ANKRD6,SLC6A8,SMARCD3,ZSWIM8,PEG10,SYT11,CAMTA1,DOCK9,ATP13A2,TST,SLC17A7" Coexpression 17597811-SuppTable6 Human Leukemia_Mullighan07_838genes GeneSigDB 1.12E-03 1.00E+00 1.06E-02 1.06E-01 135 679 "ABR,ADRB2,AP1B1,OSBPL1A,OSBPL8,AK2,ALAD,BEGAIN,GAS7,APOC2,APP,LGR5,ARNTL,ATP2A2,BID,RAB29,WASF1,BAIAP3,HIP1R,RUNX1T1,B4GALT6,TPP1,CLTB,NIPBL,CHD1L,FEZ1,SIPA1L1,PPP1R16B,ST18,RASSF2,MATR3,DAPK1,GIT2,SIRPA,DBN1,ELMO1,EEF1D,EGR3,PLXNC1,SIRPB1,ABCA8,PTK2B,FCGR1A,FDFT1,FGFR1,SEC23B,SYNCRIP,STAMBP,RASL10A,CAMKK2,ATP2C1,GAA,SEPT9,SESN1,GGT5,MALT1,BRD8,HPGDS,GLYR1,GLS,LILRB4,LILRA1,LILRA2,GRIK5,IFI16,IL6R,ITGA7,ITGAV,JAK1,KLC1,KTN1,LAMP2,MBNL1,MEIS1,MN1,CD200,FXYD6,NBL1,NINJ2,NME4,NRGN,NTRK2,OGG1,CYTL1,OLA1,ABCB1,SERPINE2,SNX10,PKM,PLEC,PILRA,TNPO2,NDUFS7,PTAFR,PTHLH,RIPOR1,PLEKHB2,RALGDS,RFX2,NUDT11,BAALC,ATP8B4,RPS6KA2,STK32B,RXRA,ATXN1,SCN2A,SLA,ARHGEF40,SLC12A4,SLC15A2,RIMS1,CAND2,CLASP2,NSFL1C,MCF2L,IQCE,KIAA0930,THBS4,TIE1,TK2,TMPO,TPD52,TRH,TTC3,DNAJC12,PITPNB,MICAL1,BEST1,LAT2,SH3GLB2,TRIM16L,MPPE1,MVB12B,NLRP3" Coexpression 16979889-Table2 Human Breast_Li06_60genes GeneSigDB 1.14E-03 1.00E+00 1.08E-02 1.07E-01 18 55 "SERPINA3,FMNL2,SYNJ2,CA8,CHN1,LONRF1,FABP7,NOP56,GAB1,DNER,RNFT2,VWA5A,MEF2C,ENPP2,XRN1,PTN,RPS6KA2,ZNF415" Coexpression M8914 Genes up-regulated in dendritic cells: unstimulated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.14E-03 1.00E+00 1.09E-02 1.08E-01 44 180 "PLA2G6,AMPH,PKP4,BMP7,DST,CALM1,CD38,SLC4A7,CDC42BPB,CSF1,SOCS5,DSCAM,ABI2,PLXNC1,NRN1,ST6GALNAC3,NCKAP1,GRIK5,ADAMTS6,KLF12,AGFG1,KCNA2,VWA5A,MATN2,CD200,MYO5A,NEFH,NUCB2,P2RX7,PLCD1,PLCL1,PPP2R5C,CNTLN,PTPN13,PEAR1,MYO18A,SLC12A2,FNBP1,SAMSN1,AHCYL2,TIAM1,USP1,VAV2,PHTF2" Coexpression M7102 Genes selected in supervised analyses to discriminate cells expressing activated beta-catenin (CTNNB1) [GeneID=1499] oncogene from control cells expressing GFP. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-03 1.00E+00 1.09E-02 1.08E-01 24 82 "AXIN2,LRBA,QKI,VCAN,YTHDC1,ABI2,PLEKHA1,NR3C1,NEK1,NRDC,PIK3C2A,MAPKAP1,PTHLH,ZNF532,FERMT1,CHD9,FBXO11,TMCC1,KDM4B,ANKRD12,KAZN,WASHC4,FRYL,ZMAT3" Coexpression M1720 Top 100 ranked genes most specific to midbrain region of adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.15E-03 1.00E+00 1.09E-02 1.08E-01 24 82 "AGT,CACHD1,VAT1L,SEMA4G,CARMIL3,MTMR2,BAIAP3,HAP1,CLGN,ECE2,PCOLCE2,EPHB1,GFRA1,PCSK1N,OPALIN,PLP1,PRPH,QDPR,ZFHX4,SLC8A3,ARHGEF40,KIAA0930,TCF7L2,SLC17A6" Coexpression 18006806-TableS2 Human Prostate_Yu07_87genes GeneSigDB 1.15E-03 1.00E+00 1.09E-02 1.08E-01 24 82 "CSMD3,SRPX,ARHGAP20,CACNB2,MYOM2,MYRIP,EDNRA,ARMCX1,FGF13,GNAL,NCKAP1L,HPSE2,MYH7,MYO6,PENK,PMP22,TNFRSF19,SNCA,DOK5,TAC1,SATB2,HHIP,TRPS1,CAMK1G" Coexpression M9118 Cluster 3: genes up-regulated in lung tissue samples from mice with tumor-bearing genotypes (activated KRAS [GeneID=3845] alone or together with inactivated PTEN [GeneID=5728]). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.17E-03 1.00E+00 1.11E-02 1.10E-01 42 170 "SNX30,MTUS1,ASPH,ATP1A1,EIF4G3,LDHD,NIPA1,OSGIN2,NRXN3,CLU,ACBD5,DNM2,ECM2,HIPK3,EMX2,EPHA5,SLC43A2,APOPT1,B3GAT1,GABRB3,B4GALNT1,SCRG1,HNMT,IGF1,KIF2A,NRCAM,PC,PDCD2,SCHIP1,PPP2R5C,DUSP15,PTGR2,SCP2,PUF60,MAGI3,SLC8A2,SLC15A2,SOX2,CAMTA1,DNAJC12,PLEKHH2,VPS35L" Coexpression M8918 Genes up-regulated in CD44 low [GeneID=960] CD8 T cells: wildtype versus RC3H1 [GeneID=149041] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.18E-03 1.00E+00 1.12E-02 1.11E-01 35 135 "ADD3,HACE1,ADGRF5,CPNE5,PROM1,NMT2,AKAP12,EARS2,DAPK1,DCC,DNM1L,GPR61,ENO2,KCNMB2,RABEPK,ANKMY1,GAD2,GALR1,ACSS1,GLRB,RAPGEF4,MSI1,KCNK10,PDE1A,PIK3C2A,PTH1R,SLC25A41,MYO18A,RUFY2,SLC11A1,SMARCE1,CMTR2,DNAJC9,SLC44A1,CDK20" Coexpression M15973 "Human orthologs of BMYB [GeneID=4605] target genes in zebra fish, identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.19E-03 1.00E+00 1.12E-02 1.11E-01 22 73 "CDC14B,ASCL1,ATP1A1,PRC1,GPSM1,PHF20L1,ELAVL4,FOXM1,TOX3,GOLGB1,SOX21,NOVA2,NUMA1,ANLN,PLP1,PCDH18,POU3F2,PTPRN,RTKN,SOX11,INKA2,HEY1" Coexpression M6880 Genes up-regulated in monocytes after HCMV infection: untreated versus BAY 11-7082 [PubChem=5353431]. MSigDB C7: Immunologic Signatures (v6.0) 1.19E-03 1.00E+00 1.12E-02 1.11E-01 40 160 "CCDC85A,ADD3,DISP3,AMH,LGR5,CALM1,DLGAP1,COL9A1,NRG2,SEC31B,ATRNL1,PLXNA4,CMTM5,HDAC4,DNAJC6,ARNT2,CALCRL,FHL1,GPR153,GCK,TOX3,ACOT7,SCIN,TUBB2B,KCND2,STXBP5,LIMS1,NCOA7,OPRL1,NXPH1,FBXW7,AMER2,CNKSR2,ZFR2,TCF7L2,TPD52,CDK20,TUBB2A,PDIA2,PLD4" Coexpression M421 Genes up-regulated in dendritic cells: immature versus mature inhibitory treated by prostaglandin E2 [PubChem=5280360]. MSigDB C7: Immunologic Signatures (v6.0) 1.19E-03 1.00E+00 1.12E-02 1.12E-01 36 140 "BEGAIN,PROM1,GPC2,CHGB,CNN3,HS3ST5,NCOR2,SV2B,PTK2B,KHDRBS3,PNMA2,NRG3,GCK,ZBTB49,HNRNPK,AGFG1,IGFBP1,IL6ST,KCNA6,LSAMP,MATN2,COL28A1,SH3TC2,ZFP30,ABLIM3,SLC11A1,CMTR2,POGZ,SSTR2,TCF7,PCDHB7,TGFBR3,UBC,SF1,NT5M,STMN4" Coexpression M8883 Genes up-regulated in hematopoietic stem cells versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.19E-03 1.00E+00 1.12E-02 1.12E-01 39 155 "ADAR,GRAMD1B,DGKZ,CDK5R1,CD38,MAP4K4,GIT2,DCTN4,SH3YL1,PTK2B,CHST15,SLC9B2,SMC2,CAMKK2,CBX1,MAP4K5,KCNF1,CD200,GPR88,PFKFB3,PFKFB4,PIK3CD,RANBP3L,CEP97,RGS3,ARMC5,LRRK2,SMPD3,HSPA4L,ST8SIA1,TNIK,SYT11,SYPL1,ANKRD12,TGFBR3,TTC3,ZFP37,TRIM9,SENP7" Coexpression M8345 Genes down-regulated in activated versus induced T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 1.22E-03 1.00E+00 1.15E-02 1.14E-01 47 196 "ADORA2A,AGT,ANK1,TMEFF1,ARSE,ATP6V1G2,BARD1,CACNA1D,KALRN,CAMK2B,BRSK2,ARHGEF2,GPR37L1,LHX2,CNTN1,C2CD2,DCC,ARMCX2,ABI1,EPB41L1,COQ7,DMTN,ERBB2,FOXM1,SEMA6C,ALDH1L1,GJB1,OS9,STMN2,GRIK5,TLX1,IL6R,KCND2,KCNH1,MN1,NTRK2,PRKAB2,RAP1GAP,ST5,ASTN2,DMXL2,LEFTY2,TNFRSF1B,R3HDM1,TNNT1,XRCC4,AP3B2" Coexpression M3321 Genes up-regulated in comparison of resting CD4 [GeneID=920] T cells versus bystander activated CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.22E-03 1.00E+00 1.15E-02 1.14E-01 47 196 "NDRG2,GPRASP2,APBA2,ATM,TIGD7,KMT2C,PREPL,ARHGAP32,DCAF8,TENM1,APOPT1,CELF1,SARAF,STAG2,ACSS1,RUNDC3A,PRRC2B,PSIP1,ADAMTS6,LINC01550,CPT1C,IL6ST,CCDC13,NELL2,TMOD2,PRKACB,PTK2,TUG1,ZNF493,RADX,FAM161B,ATXN7,SELL,ATF7IP,COA1,ANKFN1,SNRPN,RBM26,ERBIN,ROBO3,TCF7,NR2C2,TRO,LMF1,ZNF711,AMN1,KAT6A" Coexpression M4922 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee at day 3 post-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 1.22E-03 1.00E+00 1.15E-02 1.14E-01 47 196 "ADGRB1,PROM1,CAMK2A,CCNH,CDR1,RCBTB2,PNPLA8,GPSM1,ECE2,TMEM170A,KIAA0087,C8orf34,MYEF2,DTNB,DCTN4,FGF1,OLFM1,ATP8A2,PRDM5,MFSD2A,KCNJ10,KCNQ3,KPNA5,LRRC4B,SMAD9,IL17D,MN1,PC,RASGEF1B,ARHGEF10L,NUDT11,KIF16B,LINC01354,CAND2,PEG10,MIR100HG,APOM,PCDHB6,PCDHB4,UBC,AMOT,SLAIN1,TBC1D15,ZNF781,WRN,ZNF540,TUBA1A" Coexpression M8340 Genes up-regulated in BCL6 [GeneID=604] low follicular helper T cells versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 1.22E-03 1.00E+00 1.15E-02 1.14E-01 47 196 "ACHE,AGT,PCDHGB4,ATP6V1G2,ATP6V0A1,CACNB2,KALRN,SLC16A4,LOC730101,TBPL1,TENM4,ARHGEF10,VCAN,SOCS5,CX3CR1,DCC,EDIL3,SEC23B,FOXM1,SEMA6C,GABRA3,CHL1,ALDH1L1,GJB1,GRIA1,GRIK5,BTN2A1,SYNPO,IL12A,ITGAV,KCNF1,LMO1,MEST,P2RX7,PC,C19orf57,MAPK10,PROX1,PTPN13,RAD51D,RAP1GAP,FRMPD1,COLGALT2,ASTN2,TPD52,NSD2,XRCC4" Coexpression M2451 Genes down-regulated after 1 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.23E-03 1.00E+00 1.16E-02 1.15E-01 29 106 "ST3GAL5,CAMK2D,CDO1,TSPAN5,RGS17,NRN1,DPYSL4,SESN3,NFIA,NNAT,PC,PCSK5,PIK3R1,RC3H2,TNPO2,PTH1R,FAT4,RGS4,ATXN2,SLC12A2,SLC14A1,RCOR3,SOX2,ZCCHC24,SRPK2,RBFOX2,TPM1,RICTOR,SEMA3B" Coexpression M7140 Genes up-regulated in macrophages by P.gingivalis FimA pathogen. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.24E-03 1.00E+00 1.17E-02 1.16E-01 110 539 "ASIC1,GALNT13,CC2D2A,SEMA6A,LTBP4,UNC79,MAGEE2,CADPS,ATP2B1,ATP2B2,SLC2A11,FGF17,SEPT7,EVI5L,MS4A7,TAOK2,FAM19A5,DNAJB5,C4orf33,AKAP5,NRG2,HAPLN1,CSF1,NCAN,PLCXD3,FGFR1OP2,DCAF8,DGKG,BRINP1,ZEB2,KLHL3,DYNC1I1,CDON,DRP2,DSCAM,EDN1,HIPK3,FSD1L,EGFR,LINC00599,SEZ6,TLR7,EFEMP1,FGFR3,C1orf61,SEMA6C,PNMA2,DOT1L,GAD2,GFER,GNG4,FERMT2,ATP2B1-AS1,GRIK2,MFSD2A,SOX21,SLC2A6,HAS2,KLF12,AGBL5,HNF4G,FAAP20,IRF8,ST7-AS1,KCNA2,HECTD2,LSS,PACRG,SYT9,KITLG,COL28A1,NDP,NOVA1,DDR2,P2RY1,HMGCLL1,LRP12,POU3F4,RASGEF1B,RAB39A,SLC22A23,PTX3,ZCWPW1,RDX,GAL3ST4,SLC6A15,TMLHE,SLC1A2,RUFY2,EPC1,ERC1,KIF1B,SRPK2,KANK1,COBL,MCF2L,WWC1,TLL2,BHLHB9,TPD52,DOK6,CA14,VAV2,SPHK2,SHD,STMN4,HPS4,NAV2,KCNAB1,AP3B2" Coexpression M6890 Genes down-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.24E-03 1.00E+00 1.17E-02 1.16E-01 65 291 "OSBPL1A,OGT,ANK3,CFLAR,CDK5R1,CBS,MYOM2,CCPG1,KIAA1549L,TPP1,HOMER3,FAM149A,PPP1R16B,CTH,RIPOR2,DCC,PITPNC1,ZEB2,CNIH3,EIF4G2,EIF5,ST3GAL6,CHST15,FGFR3,NOP56,STAG2,IQGAP2,ERAP1,GPM6B,GUCY1A1,IL6R,KCNK1,KCNN3,LSAMP,MBP,MGAT3,MYCN,OLR1,PBX1,PDE4D,PFKP,PKD1,PSAT1,TMEM255A,SLC6A15,ZNF532,SFPQ,FERMT1,DOCK10,SHMT2,ST6GAL1,SLA,SOX11,EMC1,KANK1,TCF4,ZMYND8,CADM1,WIPF1,NSD2,KCNT2,ZBTB38,LRP8,SLC38A1,ST7" Coexpression 19204204-SupplementaryTable5 Human Breast_Parker09_1918genes_IntrinsicGenes_Compilation GeneSigDB 1.25E-03 1.00E+00 1.17E-02 1.17E-01 305 1681 "TTYH1,SERPINA3,ABAT,ASPHD1,ACADM,AS3MT,NDRG2,SORCS1,FZD9,MTA3,AGT,TBC1D14,KIAA1324,AK2,ALCAM,AMPD2,OGT,CDC42BPA,ANK3,LCORL,PPFIA1,ANXA7,CNTNAP1,APBB2,BCAS1,PDXK,ZSCAN18,EIF4G3,ATP2B1,ADAM15,ADGRB2,SEC11C,CFLAR,BMP7,DST,FUBP1,MTMR2,SGCE,CACNA1G,CA8,CA12,CALB1,CALM1,CANX,CAPN3,PRC1,CBR1,CBS,CCK,CCNH,AIFM1,CD38,ENTPD6,NEURL1,DGKI,AP4M1,LRBA,REPS2,LRRFIP1,CDO1,CLGN,ADGRG1,CHGB,CHI3L2,CLU,CLTC,FADS2,CNN3,COL4A5,COL9A1,LETMD1,COL9A3,COL11A2,TBPL1,BAG4,CP,PNKD,LRIG1,OSBPL3,CNTNAP2,CTNND2,BOC,SNPH,SCRN1,DBI,DBN1,PITPNC1,ARMCX2,ZEB2,MFAP3L,FBXO25,PARD6A,AK5,RABGAP1L,FAM107B,ARNT2,RAB39B,DMD,DPYSL2,E2F5,EDNRB,EEF1A2,FEM1B,EGFR,MBNL2,KCTD3,EIF4G1,STARD3NL,EPB41,LRRC17,ERBB2,EFS,SPEG,TLR7,ECSIT,AMZ2,FABP7,TUBB3,ATP8A1,RACK1,TESK2,FECH,OLFM1,FGF12,FGF13,FGFR1,FHL1,UBE2E3,CAP2,IQCG,FLT1,ZBED3,FAM49B,GAD1,NEK6,IQGAP2,SYT17,ACSS1,GART,WASF3,GATM,GFRA1,GJB1,GLDC,DBF4,RAB30,STARD3,OS9,GNAS,GPT2,LNX1,ADGRA3,GPD1,GRIA1,GRIA2,DIDO1,CIT,PTPRT,GSN,TMEM25,GYG1,MUM1,MAEL,PADI2,ZHX1,ELOVL5,ACOT7,GABARAPL2,HSF2,IGF1,SCIN,IL6ST,INSM1,ITGA7,KCNC2,KCNK1,KIT,STMN1,LIFR,MAOB,MAPT,MID1,AFDN,MN1,COMMD5,THYN1,MX1,MXI1,MYO6,TCEAL5,FXYD6,NDP,NELL2,NFIA,NFIX,NME4,NPY,SLC11A2,NUCB2,NUMA1,ODF2,PBX1,PCSK1,PDE4B,PDGFRA,PFKFB3,ANLN,PIK3R1,ZFYVE21,RETREG1,KCTD15,GPSM2,JAKMIP1,FTO,PLXNB1,PNMA3,FA2H,POLR2F,PRKAB2,PRKACB,MAPK3,KLK6,SYTL2,PTHLH,PTN,PTPRN2,PYGM,QDPR,RAB3A,RAD17,RAD52,RAP1GAP,ENOX1,RBBP8,ZDHHC14,BSDC1,RDX,MORC4,RGS10,ZFHX4,ZNF532,RPL15,SMPD3,GALNT10,MRAS,CPEB3,MYO18A,MAGI3,SLC1A2,SLC4A3,SLC20A2,CPEB4,CXXC4,GKAP1,SMARCE1,SNRPN,CAND2,PEG10,BEX1,DBNDD2,SPTAN1,SPART,ITPRID2,MESP1,NEK4,CEP68,STX1A,GSE1,PLCB1,DDHD2,IQCE,MGRN1,TCF7L2,TRIM2,TCF12,PSD3,PCDHA6,TMEM121,TGFBR3,TNS1,TP53BP2,TPD52,TPM1,TRH,PDSS1,TRPS1,TMPRSS5,HSPBP1,UCHL1,DNAJC12,MTCH1,VAV1,NPDC1,SLC13A3,ZNF24,DNALI1,LRP8,LMAN2L,SEMA3B,NAV2,ITM2C,WIPF2,HRASLS,ACTR3B,IFT88" Coexpression M262 Genes discriminating responses to sodium arsenite [PubChem=26435] from other stresses. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.26E-03 1.00E+00 1.18E-02 1.17E-01 51 217 "SPARCL1,OGT,APBA2,ARNTL,ATP6V0A1,BCL2L2,ST3GAL5,CARS,CCPG1,TPP1,DNAJB5,CTH,DNAJB6,DYRK1A,E2F6,ASB3,RPS6KC1,TAOK3,DLC1,FOXO3,ATP2C1,AP4B1,GOLGB1,CIT,GUCY1A1,HPS5,KLF12,HSPA1L,IL6ST,KCNF1,KIFC3,MT3,NFE2L2,ANLN,PLTP,MAPK7,PTPRB,RALGDS,REV3L,HSPA4L,CPEB4,SRPK2,TBL1X,ZMYND8,TSC1,UBE2H,ZNF24,ZNF184,ZSCAN26,ZFAND5,FXR1" Coexpression 20460173-ImmPortAnti-IgMvsControl Human Immune_Kong10_1790genes_ImmPort_Anti-IgMvsControl GeneSigDB 1.27E-03 1.00E+00 1.19E-02 1.18E-01 216 1152 "RALGAPA1,ABR,ACLY,ADD1,ADD3,ADORA2A,AP1B1,ALCAM,BCAR3,ALK,MRTFA,AMPD2,APOC2,LGR5,SHROOM2,MADD,CASK,RGS20,ARRB2,ASPH,PCDHGB4,ATP1A3,NOL4,ATP6V0A1,BARD1,BCL2L2,BCL7A,BID,CFLAR,SGCE,BTRC,CALM1,CBS,ARHGEF1,CD38,CD81,AP4M1,LRBA,ARHGEF2,CDC25B,CDC42,CDH2,LRRFIP1,UBE2L6,COPB2,RCBTB2,FOXN3,PPT2,MYL6B,CLTA,TJP2,SULT4A1,LY86,ARHGEF6,LETMD1,COX4I1,CREM,CRY2,RNF14,CS,ARHGEF10,OSBPL3,PPP1R16B,HDAC9,DCAF8,TBC1D5,RIMS3,MAML1,PHYHIP,TOMM20,IP6K1,ELMO1,GSDME,G3BP2,RABGAP1L,DPYSL2,ABI1,GNE,DNAJB6,DYRK1A,ABCC5,RASGRP1,CELSR3,EGR3,EIF4G2,EPB41,MFSD10,EPB41L2,RCAN2,RASGRP2,EPS8,ERCC2,DENND4A,NCALD,EXTL2,PTK2B,TUBB3,RACK1,ST3GAL6,CHST15,FGR,ATP5PD,NPTN,CSPG5,FYN,GAP43,MTHFD2,GCNT2,MALT1,GLS,FERMT2,GPD2,LILRA2,GPER1,NUDT21,GRIK2,GRM5,CIT,HAS2,PACSIN2,NCKAP1L,ATXN2L,KLF12,ELOVL5,GABARAPL2,AGFG1,SMAP1,IRF8,IDH3A,IFI16,INPP5B,ITPKB,KCNK1,KCNN3,KHK,STMN1,LSS,MAN2A2,MARK3,MAT2A,AFF1,CD200,PTOV1,MT3,MTR,MX1,MXI1,NASP,SLC11A2,SETD4,OCRL,OGG1,PCDHGC3,PDE2A,ABCB1,PKM,PMP22,PTPA,PPP2R5C,PRKCB,PRPSAP2,CNNM2,NDUFS7,PSMA6,PTCH1,PEX5,RPE,SAFB,SEC14L1,SGK1,FAM102A,ST6GAL1,CLSTN1,SLC2A5,SLC12A4,SMARCA4,LIMCH1,SRPK2,TAB2,POGZ,SS18,NCDN,SYP,SYPL1,ADGRL3,KIAA0930,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA6,PCDHGA3,PCDHGA2,PCDHGA1,ITGB3BP,TMPO,RBFOX2,TPM4,METTL3,ZMYND8,RUSC1,SSBP2,ZKSCAN5,TUBB2A,PITPNB,NSD2,CLDND1,ZNF177,MAP3K12,LRP8,RNF103,PHTF2" Coexpression 16498405-TableS3 Mouse Kidney_Takemoto06_388genes_cat1 GeneSigDB 1.27E-03 1.00E+00 1.19E-02 1.18E-01 67 302 "METAP1D,C1QTNF1,ADGRF5,PRX,THSD7A,LDB2,MYOM2,LRRFIP1,SNCAIP,DOCK4,COPS7A,MAGI2,EDNRB,OPTN,EML1,CALCRL,PLEKHO1,FLT1,FYN,GABRA4,PCDH17,STON1,PARD3B,WIF1,SYNPO,ITPKB,LMO2,MAPT,MEF2C,MEIS2,MEST,MMP17,CD200,NAP1L1,NBL1,NCF2,NELL2,SERPINE2,SERPINI1,SCHIP1,LRRC49,PTN,PTPRO,RIPOR1,ZDHHC14,ROBO2,MAPK12,GALNT10,SGK1,SMARCA4,PALLD,UNC5B,DDN,CLASP2,RHBDL3,TMEM150C,PDLIM2,ZEB1,TNS2,TJP1,DAAM2,RBFOX2,WBP2,NR2C2,UBC,CRB2,RTN4" Coexpression 16166195-TableS1b Mouse Testicular_Denolet06_342genes GeneSigDB 1.28E-03 1.00E+00 1.20E-02 1.19E-01 58 254 "AS3MT,EMILIN3,ADCYAP1R1,BIN1,PKP4,ANXA7,PDXK,ARHGDIG,CADM3,MPDZ,RGS11,CBR1,RGN,CDH10,LARGE1,CRLF1,CNN3,LRIG1,HEPH,SLC29A4,EDN1,HEYL,PLXNC1,EFS,PIPOX,FAM198B,FABP7,SPSB4,FGFR1,MSL3,GSTT2,GUCY1B1,RASSF8,PADI2,SCIN,KCNA6,KCNK1,MATK,MYCN,NEFM,CDK14,EPDR1,CNTLN,PTPRD,PTPRZ1,WLS,SEMA6D,SATB1,RASA3,BCAN,SLC1A6,FAM81A,SLC37A2,ZFPM2,MICAL1,VSNL1,FMN2,HRASLS" Coexpression M8662 Genes down-regulated in bone marrow-derived macrophages: untreated versus stimulated by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.29E-03 1.00E+00 1.20E-02 1.19E-01 44 181 "RNF157,AP2A2,UPRT,NCOA1,CERS5,ARHGEF1,FOXN3,CLTC,C2CD2,GAPVD1,SIRPA,SEC16A,DOCK2,SNX29,VPS13B,SLC43A2,RTN3,FER,SESN1,MAN1B1,SFXN5,LMO2,MBNL1,MEF2C,SCAMP5,TBC1D25,EPN1,PPP3CA,SNRK,ZDHHC14,UBR7,RXRA,SEC14L1,ITSN1,KIF16B,ST6GAL1,ATF7IP,FNBP1,ATMIN,RGMB,ZBTB14,MAP3K12,HPS4,ADAMTS10" Coexpression M10277 The 'NPM1 signature 3': genes up-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.29E-03 1.00E+00 1.20E-02 1.19E-01 74 340 "AK2,ALK,FAM131A,CAPRIN2,ATM,CFLAR,CDK5R1,DST,CACNA1I,CA12,CACNA2D1,CHGB,TJP2,NIPBL,HOMER3,CNR1,COL4A5,DZIP3,CTH,DGKG,IP6K1,FEM1B,FRY,MBNL2,KMT5B,PDLIM5,CELF1,STAG2,ARFIP1,PPARGC1A,GK,MCHR1,KIF3A,HMGB1,AGBL5,HSP90AA1,LAMA2,LIMS1,MAN2A2,MEIS1,NCAM2,NFE2L2,CNOT4,DPY19L2P2,PCDHGC3,PDE3A,PDPK1,SNX10,SCHIP1,PPP3CC,PKN2,APTX,SPDL1,LGR4,PLPPR3,ASRGL1,SH3BP2,ARHGEF40,SLC15A2,ATF7IP,SMARCD3,SON,ZBTB43,SRPK2,SEPT8,ZFR2,MTCL1,IQCE,DOCK9,TMPO,CHST5,TST,SH3GLB2,WNK1" Coexpression 16849537-Table1 Human StemCell_Davicioni06_81genes GeneSigDB 1.29E-03 1.00E+00 1.20E-02 1.19E-01 23 78 "ABAT,ALK,ANK2,TMEFF1,MARCH3,JAKMIP2,RASL10A,MSTN,GPM6B,INPP1,KCNN3,VWA5A,MN1,MYCN,NEFM,NELL1,NRCAM,PKIA,MORC4,MEG3,SGK1,TCF4,TCF7L2" Coexpression M12653 "Down-regulated genes in B-CLL (B-cell chronic leukemia) patients expressing high levels of ZAP70 and CD38 [GeneID=7535;952], which are associated with poor survival." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.31E-03 1.00E+00 1.22E-02 1.21E-01 19 60 "ALCAM,EIF4G3,ATP2B1,SYNJ2,SLC4A7,SLC4A8,SOCS5,CNTNAP2,USP6NL,TCAF1,DGKG,EGR3,BACH2,MEF2C,NUCB2,PTK2,ZNF532,TCF7,TPD52" Coexpression M18328 Top marker genes in medulloblastoma associated with good response to treatment (good outcome). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.31E-03 1.00E+00 1.22E-02 1.21E-01 16 47 "ASIC1,AMT,CRMP1,ELN,RASL10A,GAP43,GNAS,NBL1,NHLH1,NTRK3,HERC2P3,C19orf57,RALGDS,RTN1,SATB1,AP3B2" Coexpression 19861896-Table1 Human Brain_Castells09_50genes GeneSigDB 1.31E-03 1.00E+00 1.22E-02 1.21E-01 16 47 "CDH2,LHX2,CTNND2,FABP7,NEK6,GFAP,PPARGC1A,GPM6A,GPM6B,GPR17,NCAM2,PDE4B,PTPRZ1,SH3GL3,SMARCD3,TEK" Coexpression M6376 "Genes whose promoters where bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer), according to a ChIP-chip analysis." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.31E-03 1.00E+00 1.22E-02 1.21E-01 97 467 "SERPINA3,DPP10,APBB1,ATM,ATP2A2,B3GALT2,BMP7,BTRC,CBFA2T2,SEPT7,ARHGAP33,CDH18,FBXO7,CCDC151,PICK1,CNTN1,SIPA1L1,PDE4DIP,PLXNA4,CFAP61,FGFR1OP2,LIN54,POM121,MAMLD1,FARSB,YAF2,IRAK4,LRRC23,ATP13A4,ZCCHC17,HVCN1,AK8,MEGF10,TUBGCP4,ARFIP1,GFER,FERMT2,SPACA9,FRMD5,PTGDR2,ARHGAP19,DHX35,DOCK7,DIPK1A,KCNMA1,L1CAM,VWA5A,ZFYVE27,CHST6,IL17D,DBNL,MSRA,PDGFRA,PKD1,GDPD2,PTAFR,PTHLH,SUSD4,CRTAC1,ARMH4,SGSM1,MEG3,STX1B,NCBP3,FAM182A,ZFP2,AMBRA1,CHD9,CCDC92,SLC1A3,BTBD3,SLC8A3,KBTBD4,TMEM132D,CABCOCO1,SOX15,LMO3,ZSCAN29,SULF2,JMJD6,DNMBP,ANO4,ZFP90,SPX,THBS4,SLC44A1,CBX5,ASXL3,DDHD1,RIMBP2,GUSBP1,USP32P2,UBE3B,PAK5,SNX14,SOCS4,SLC4A10" Coexpression M1969 "Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent tri-methylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-03 1.00E+00 1.24E-02 1.23E-01 33 126 "NCKAP5,ADARB2,ZNF521,CALY,PLCXD3,PHYHIP,KLHL5,EXTL1,TPPP3,MEGF10,LOXL3,GRM3,GUCY1A1,BRINP3,KCND2,KCNJ5,MEIS1,NRBP2,OPCML,KCNK10,PDYN,PTN,ROBO2,TRIM46,YPEL4,SNCA,C11orf87,PCDHGA1,CA14,VAV1,KCNAB1,PAK5,TMEM63C" Coexpression M19629 The 'NPM1-mutated signature 1': genes down-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to all AML cases with the intact gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-03 1.00E+00 1.24E-02 1.23E-01 33 126 "ACLY,ADAR,LTBP4,DGKD,CAPN3,RUNX1T1,WHRN,CS,PPP1R16B,SCRN1,EEF1D,LPAR6,PLEKHO1,ZMYND10,FHL1,CAMKK2,TPPP3,GAD1,GPM6B,CD200,NBL1,PDE2A,PDE4D,RETREG1,POU6F1,PSMA6,SNRK,EMC1,SPTAN1,TCF7,ZNF384,KCNE5,LAMP5" Coexpression M3854 Genes down-regulated in mice with skin specific double knockout of both RB1 and TP53 [GeneID=5925;7157] by Cre-lox. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.34E-03 1.00E+00 1.24E-02 1.23E-01 119 591 "TMCC3,SNX30,TAOK1,MRTFA,ANK3,APP,LGR5,IGDCC4,RASL11B,ATM,BACH1,FUBP1,DDR1,CAMK2B,CANX,ARHGEF25,NEURL1,ZMYM4,ADGRG1,CLCN3,CLU,TJP2,COL9A3,CRYM,TENM4,PDE4DIP,CX3CR1,MAML1,DCT,DLX1,DMD,EDN3,EFNA3,EGFR,ELN,EPHA5,SRRM1,PRMT5,SCARA3,ATP5PD,AFF2,CAMKK2,CELF1,ZMYND11,GALR1,USP19,TXNL4A,TNRC6A,OS9,GRK4,CACFD1,KAT7,AP4S1,BACH2,FAAP20,LAMA2,SMAD1,MAP4,MBP,MEIS2,MYH3,MYH6,NDUFA5,NFIA,NPY,NUMA1,GLIPR1L2,PAX6,PDE3A,TMOD2,PKD1,PLEC,PLXNB3,FA2H,POLG,MASP1,PTPN13,PTPRE,RBBP6,RBBP8,ZDHHC14,MYH14,BAALC,RYR1,TNFRSF19,SCMH1,SMARCA4,INTS9,SNCA,SON,SOX2,SOX5,SOX11,ERC1,UNC5B,NCDN,RHBDL3,PLCB1,ATP11A,PJA1,WWC1,TRIM2,FRYL,HHIP,SLC44A1,THRA,TNNT1,RBFOX2,TRH,TRO,SSBP2,UBC,UBE3A,WRN,CELF4,ZSCAN26,PMEPA1,NAV2,NHSL1" Coexpression M2997 Genes up-regulated in B lymphocytes: wildtype versus ZFX [GeneID=7543]. MSigDB C7: Immunologic Signatures (v6.0) 1.35E-03 1.00E+00 1.25E-02 1.24E-01 40 161 "GPAM,DST,CACNA1G,CACNA1E,CD38,DGKI,ADGRG1,TJP2,LRIG1,TOX,TBC1D5,ZEB2,SRGAP3,CPEB2,FAM78B,SNX29,FRY,PLEKHA1,ST6GALNAC3,FYN,TOX2,IL6ST,JAK1,CREG2,KIF5C,MEF2C,MX1,SEPT4,PACSIN1,RAB5B,OXR1,PRR5L,CHD9,RUFY2,RAP1GAP2,SYT11,DNAJC9,TRPS1,MEIS3,SSPN" Coexpression M16734 "Genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer) by ChIP-chip assay on a 12K CpG array (high-CpG-density promoters, HCP)." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.35E-03 1.00E+00 1.25E-02 1.24E-01 27 97 "CSMD3,ALCAM,NOL4,CA12,NRXN3,ELMO1,RASGRP1,EN2,ERBB4,KIAA1109,TRIM16,GRIA4,HPSE2,MAPT,MARK1,IRX1,PTPA,FEZF2,ERI2,ST8SIA1,SLC1A2,LIMCH1,SNAP25,CADM1,RGMA,HPS4,KCNAB1" Coexpression M462 Genes up-regulated in CD4 [GeneID=920] T cells: control versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.35E-03 1.00E+00 1.25E-02 1.24E-01 34 131 "NDRG3,USP28,UPRT,CBFA2T2,FOXN3,SLC22A6,ABI3BP,SPATA2,PLEKHM1,G3BP2,EML1,RASGRP2,CDKL3,GALC,GLRB,ZBTB49,AGFG1,LSAMP,MMP16,NF1,PPP3CC,CNNM2,EML5,MORC4,SEC61A2,MRAP2,ELMOD1,ABLIM3,KDM4B,ROBO3,DDHD1,RASD2,VAV1,ZIC3" Coexpression 14695196-Table4 Human Colon_Mariadason03_308genes GeneSigDB 1.36E-03 1.00E+00 1.26E-02 1.25E-01 52 223 "ACLY,KIDINS220,SEMA7A,MIER1,ATP1B3,NAE1,CACNB2,MYL6B,CLTB,CSNK1E,GREB1,SEC14L5,LONRF1,EGR3,PLXNC1,LPAR6,EIF5,LRRC23,ATP8A1,FCGRT,ANKFY1,GAA,SPIN1,PSIP1,MAP4,MEF2C,MGAT3,MITF,MRPL42,CCDC80,NNAT,SLC11A2,PDE4D,ABCB1,APTX,RFX2,ZNF532,ZC3H14,SFPQ,OGDHL,ZHX3,GLT8D1,CLASP2,SST,KANK1,ARC,TCF4,ICAM5,TTC3,HIRA,UCHL1,EVI5" Coexpression M1871 Set 'ES exp1': genes overexpressed in human embryonic stem cells according to 5 or more out of 20 profiling studies. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.37E-03 1.00E+00 1.26E-02 1.25E-01 81 379 "ADD2,NLGN4X,MTA3,SEMA6A,CACHD1,TMEFF1,CAPRIN2,ATP1A2,ADAM23,PROM1,FUBP1,MAP7,CBS,SYNGR3,DCLK1,CRMP1,LRIG1,CNTNAP2,PITPNC1,G3BP2,RABGAP1L,DLG3,DNAJB6,AASS,LINC00599,ERBB2,ETV1,PIPOX,ZNF589,OLFM1,FGF13,FGFR1,MAD2L2,NOP56,GABRA5,GABRB3,GAD1,MTHFD2,GART,GLDC,GPM6B,GPR19,NUDT21,DIDO1,KAT7,PSIP1,TUBB2B,KIF5C,MAT2A,NASP,NODAL,PDCD2,CAMKV,EPB41L4B,PPM1B,PPP2R2B,PTPRZ1,RBBP8,ROBO1,LGR4,SALL1,ST6GAL1,SLC6A8,SEPHS1,SNRPN,SOX2,RAP1GAP2,KLHL7,COBL,SIRT1,CBX5,TMPO,TNNT1,VSNL1,SLC13A3,ZIC2,ZIC3,ZNF195,LRP8,SLC38A1,FXR1" Coexpression M5569 Genes up-regulated in comparison of effective memory CD4 [GeneID=920] T cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.26E-02 1.25E-01 47 197 "KIAA1324,PKP4,GAS7,PLA2G4C,NRP2,CACNA1E,CALM1,CH25H,CRLF1,CLTC,NECTIN3,CRY2,CX3CR1,JAKMIP2,SNAP91,ST8SIA3,EXTL2,ADGRV1,TUBB3,KIAA1109,FGR,RASL10A,SIGLEC8,PCSK1N,GPER1,TUBA1C,ITGAM,MAOB,MATK,CAMKV,NLE1,TRHDE,CDIP1,ZDHHC14,RFX2,DGLUCY,CHD9,MYT1L,SPATA7,RAP1GAP2,SYNE2,KLHL4,SZT2,RIMBP2,TNFRSF1B,TRPM2,ZNF74" Coexpression M4530 Genes up-regulated in comparison of unstimulated NK cells versus those stimulated with IL2 [GeneID=3558] at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.26E-02 1.25E-01 47 197 "KLRC4,ATM,MTMR3,CHRM4,C2CD2,CRYBB1,ZFYVE16,YTHDC1,PLEKHM1,KLHL3,DLG2,SIDT2,BSCL2,KIAA1109,IP6K2,FOXO3,PRELID3A,FYB1,MSL3,POLL,MCHR1,MAN1B1,LMO1,ARHGAP12,AFF1,MXI1,NACA,NUMA1,C11orf49,SIDT1,BSDC1,RPS6KA2,DGLUCY,ATXN1,ST6GAL1,SLC1A7,SLC6A11,KDM3A,IZUMO4,MYCBP2,KIF1B,APOM,FAM208A,SIK3,METTL3,SLC26A10,PARP6" Coexpression M4431 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus naive B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.26E-02 1.25E-01 47 197 "PARG,MARCH3,SLC4A4,MTMR9,ATP6V0A1,BTK,DDR1,USP2,LARGE1,CLCN4,LY86,CNR1,SOCS5,HDAC9,MYEF2,TIAM2,RHOBTB1,CORO2B,GABBR1,CHL1,GATM,GPM6A,IRF8,MEF2C,MKLN1,CD200,CDK14,STRN3,HYDIN,MTMR10,RIPOR1,RAD51D,RADX,ZNF532,C12orf49,RMI1,ZNF821,CPEB3,SLC2A5,IDI2-AS1,PEG10,NEK4,TCF4,TMOD1,TRIO,EVI5,DPF3" Coexpression M9800 Genes down-regulated in B lymphocytes: naïve versus plasmablasts. MSigDB C7: Immunologic Signatures (v6.0) 1.37E-03 1.00E+00 1.26E-02 1.25E-01 47 197 "NDRG3,ADORA3,GAS7,ATM,ATP2B1,GPR146,ZNF555,CCPG1,RCBTB2,FAM189A2,ARHGEF6,CNRIP1,AATK,FEZ2,RHOBTB1,LPAR6,RTN3,FCGRT,ZBED3,SEPT9,GPR34,MAN2A2,MBP,TM6SF1,MEF2C,NCF2,NRGN,PDE3B,PRKACB,GDPD1,ZNF844,SLC25A48,ASRGL1,KIF13A,ZCCHC24,CAND2,SLC37A2,TACC1,MTCL1,TCEA1,TLR4,TPM1,DCBLD1,CCDC14,P2RY12,ATP6V0E2,MPPE1" Coexpression M7224 Genes up-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 1.40E-03 1.00E+00 1.28E-02 1.28E-01 46 192 "NCKAP5,SLC12A5,CARNS1,SEMA7A,DLGAP3,AKAP12,RIMS3,PLPPR4,CHRDL1,HS3ST2,FAM78B,EDN1,ZIC4,B3GAT1,NRG3,PHYHIPL,NKX6-2,MYOZ2,CSDC2,NTNG2,PCDH11X,GNAL,WDFY3-AS2,HTR2A,NKX2-2,NRCAM,OGDH,SLC10A4,PENK,PLIN1,TMEM235,PTPRZ1,KLHDC8A,LINC00461,SGK1,SH3GL2,CNKSR2,PREX2,LIMCH1,ARHGAP26,SAMSN1,RGL1,SULF2,VSNL1,ZNF28,PLSCR4" Coexpression M1514 Down-regulated genes in the signature of adipose stromal cells (ADSC) immortalized by forced expression of telomerase (TERT) [GeneID=7015]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.40E-03 1.00E+00 1.29E-02 1.28E-01 28 102 "ACHE,CDH2,ARHGEF6,CNR1,DNM1,ABCC9,TSPAN5,EFNA3,EGR3,RASGRP2,FGFR1,GHR,GLUL,GRM7,MOBP,NTRK2,GPR88,OPRL1,PDE4D,SERPINI1,ST8SIA5,PMP22,PPP2R2B,RGS12,SH3BGR,ZFPM2,TGFBR3,THBS4" Coexpression 20058202-Table5 Human StemCells_Secco09_29genes GeneSigDB 1.42E-03 1.00E+00 1.30E-02 1.29E-01 11 27 "HECW2,AGT,RIMS3,EBF1,ELN,EPHA5,ITGA7,PDE1C,ENPP2,SPP1,EPB41L3" Coexpression M2380 Genes down-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-30 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.42E-03 1.00E+00 1.30E-02 1.29E-01 11 27 "TAOK1,PCDH10,TMEFF1,ATP2A2,RABGAP1L,NCAM1,CPEB3,CHD9,ADGRL3,ANO4,SATB2" Coexpression M14487 Genes directly up-regulated by CD44 [GeneID=960] stimulation of B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.42E-03 1.00E+00 1.30E-02 1.29E-01 11 27 "ADRB2,ATP1A2,CAMK2D,GCNT2,MITF,NBL1,HERC2P3,RGS3,SH3BP2,SOX5,STX1A" Coexpression 16230383-Table2 Human Sarcoma_Baird05_12genes GeneSigDB 1.42E-03 1.00E+00 1.30E-02 1.30E-01 5 7 "FGFR3,FLT1,JAK1,KIT,PDGFRA" Coexpression M8416 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 10 h time point that were not down-regulated at the previous time point, 8 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.43E-03 1.00E+00 1.31E-02 1.30E-01 18 56 "MTUS1,RGS20,LOC730101,NIPBL,RHOBTB1,FRY,ETV1,STAMBP,NR3C1,OGG1,RAD17,SCN8A,SON,ST5,ANKRD28,TCF7L2,ZNF23,ZSCAN26" Coexpression 15150091-Table4 Human Viral_Schaefer04_56genes GeneSigDB 1.43E-03 1.00E+00 1.31E-02 1.30E-01 18 56 "APLP1,APP,GYG2,CDH2,CRMP1,DAPK1,DPYSL2,TUBB4A,FCGRT,FHL1,DPYSL4,GAP43,GATM,IFI16,ITGA7,MN1,PTPN13,TNNT1" Coexpression 16474848-SuppTable1 Human Prostate_Hooi06_65genes_2FoldChange GeneSigDB 1.44E-03 1.00E+00 1.31E-02 1.30E-01 54 234 "FMNL2,ALK,ANK3,PPFIA4,FUBP1,C5,CALB1,LRWD1,NOG,CLCN4,NECTIN3,FAM131B,SRGAP3,TMTC1,ENO2,FHL1,FLNC,SYT17,CPLX1,PCSK1N,GPD2,STON1,ADAMTS6,IL6ST,METTL21A,VWA5A,MBNL1,IL17D,MEST,MYO6,PAK3,PFKFB4,CCSER2,KCTD15,PPP2R5E,SLC22A23,PTK2,ROBO1,CLIP1,ITSN1,SLC14A1,TET1,PEG10,ARHGAP26,SYT1,TBL1X,TCF7L2,OBSL1,AHCYL2,TPM4,RGMB,LRP8,PRDM10,WNK3" Coexpression 20388125-TableS1 Human Stomach_Wang10_112genes GeneSigDB 1.44E-03 1.00E+00 1.32E-02 1.31E-01 29 107 "PTCHD1,SORCS2,ADGRF5,ASTN1,SYT6,CHRM4,PDE4DIP,SLC45A1,TMCC2,DLG2,EBI3,CDHR1,FHL1,CGREF1,GABRA4,ATCAY,PPM1L,NRCAM,PTH1R,CNTNAP3,IL17RB,USP33,SOX10,SPTB,RAP1GAP2,SYN1,TAC1,GALNT17,SLC26A10" Coexpression M9025 Genes up-regulated in chronic lymphocytic leukemia (CLL) samples bearing deletions in the 13q14 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.44E-03 1.00E+00 1.32E-02 1.31E-01 22 74 "ASPHD1,NDRG2,ARHGAP20,USP37,C1orf52,CDC27,USP6NL,KLHL5,EXTL1,RASGEF1B,ZIK1,PTPRO,SLC15A2,KDM4B,WASHC4,CLASP1,NAT16,ARL10,TPD52,SGK3,ZNF24,PHTF2" Coexpression M2334 Genes translationally up-regulated by serum in MEF cells (embryonic fibroblast) lacking TSC2 [GeneID=7249]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.45E-03 1.00E+00 1.32E-02 1.31E-01 14 39 "ATP1A1,ANKRD35,DDX46,TBC1D16,TUBB2B,NUMA1,FAM98B,GON4L,CCDC88A,SMARCA4,BDP1,KIF1B,SMG6,DICER1" Coexpression M2540 Gamma and UV responding genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.46E-03 1.00E+00 1.33E-02 1.32E-01 25 88 "SEMA7A,ATP6V0A1,BCL2L2,NRP2,LDHD,CCNH,COPB2,CRHBP,EML4,HPCA,IGFBP1,DIPK1A,ITIH2,ITPKB,MEF2C,PBX1,PLCL1,PPP3CA,RBBP6,SLC1A3,SLC6A1,TCF4,TPM1,SLC26A10,DNALI1" Coexpression 15545975-Table1 Human Colon_Arango04_254genes GeneSigDB 1.47E-03 1.00E+00 1.34E-02 1.33E-01 43 177 "ACLY,BIN1,MIER1,ASCL1,ASPA,CDC25B,RCBTB2,MYL6B,CLTC,COL4A5,BTF3L4,TBPL1,CLOCK,PUM1,DLG3,VPS26C,RTN3,HBS1L,INPP5K,COPS8,GNAL,SHISAL1,LIFR,LIG4,MYO5A,NF1,NFIX,NFYA,NUCB2,PTPRZ1,ATXN2,DZIP1,FAM81A,FNBP1,BEX1,ADHFE1,TCF7,PSD3,GZF1,TIAM1,PDSS1,TSPAN11,DNALI1" Coexpression 15831674-Table1 Human Breast_Itoh05_98genes GeneSigDB 1.47E-03 1.00E+00 1.34E-02 1.33E-01 20 65 "SERPINA3,DST,GREB1,DSCAM,EGR3,ARMCX1,FDFT1,OLFM1,FHL1,CAP2,ELOVL5,IGSF1,PRRX1,ELOVL2,PPM1E,SOX3,CLSTN2,TIAM1,TST,ST7" Coexpression 15459216-TableA2f Human Leukemia_Haslinger04_126genes GeneSigDB 1.48E-03 1.00E+00 1.34E-02 1.33E-01 30 112 "OGT,EP400,ATP2B1,BCL7A,FUBP1,HIP1R,MAP4K4,CS,GIT2,DNM1L,CELSR3,RASGRP2,TAOK3,OS9,RNFT2,IRAK3,NCKAP1L,MAN2A2,NAP1L1,RAB5B,RASGRF1,ATXN2,SHMT2,R3HDM2,SLC2A5,ERC1,WASHC4,TRIO,ZBTB16,ST7" Coexpression M1878 Exercise regulated genes in hyppocampus. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.48E-03 1.00E+00 1.34E-02 1.33E-01 12 31 "GPR37L1,MAGED1,GAD1,GIT1,NPY,NPTX2,NTRK2,SLC6A1,SYN1,CADM1,VGF,SCG2" Coexpression M816 Top highly correlated genes positively associated with poor survival of patients with suboptimally debulked ovarian tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.48E-03 1.00E+00 1.34E-02 1.33E-01 12 31 "THSD7A,RUNX1T1,CCPG1,SRSF11,EFEMP1,FAT4,REV3L,LIMCH1,PSD3,SIRT1,ZBTB16,KCNAB1" Coexpression M11023 Down-regulated genes from the set G (Fig. 5a): specific to cells expressing both MLL-AF4 [GeneID=4297;4299] and AF4-MLL fusion proteins. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.48E-03 1.00E+00 1.34E-02 1.33E-01 13 35 "DGCR6,LRCH2,NMT2,FAM171B,VCAN,ELMO1,RAB39B,ETV1,MEGF10,GPR19,RPS6KA2,SLC6A8,NSD2" Coexpression M5522 Genes down-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.48E-03 1.00E+00 1.34E-02 1.33E-01 13 35 "SHTN1,C1QL2,RGS17,GAD1,C1orf94,VWA5A,PIK3R1,PTPRN,ZDHHC14,RTN1,ZHX3,AJAP1,FLRT2" Coexpression 12791645-Table5 Human BoneMarrow_Croonquist03_39genes GeneSigDB 1.48E-03 1.00E+00 1.34E-02 1.33E-01 13 35 "OSBPL1A,AMPH,CD86,LY86,CX3CR1,SV2B,ETV1,GATM,GPM6B,NPR2,PCDHGC3,PDE3B,MRAS" Coexpression 18794137-SuppTable1d Human Breast_Creighton08_453genes GeneSigDB 1.49E-03 1.00E+00 1.35E-02 1.34E-01 65 293 "SERPINA3,ABAT,ADD3,ADORA1,CA12,CALB2,LARGE1,LRWD1,CHN1,NRXN3,TPP1,COL4A5,LRIG1,ATRNL1,VCAN,GREB1,NOS1AP,MED24,DSCAM,EGR3,RASA4,DLC1,FDFT1,PRMT5,OLFM1,TMEM164,MAD2L2,FOXO3,GLS,KCNMB4,GRIK3,ARHGAP36,ELOVL5,HNMT,IGSF1,TUBB2B,ZNF385B,JAK2,KCNJ3,LAMP2,SYTL4,MAPT,LYPLAL1,KCTD6,AFF1,PIK3R1,FTO,APTX,ELOVL2,RBBP8,RFX5,RPRD1A,ELP2,IL17RB,SFPQ,SYBU,MYO16,SPART,SRPK2,CEP68,TBL1X,SIK3,TST,SGK3,CADM1" Coexpression M9885 Genes down-regulated in CD4 [GeneID=920] T cells with NRAS [GeneID=4893] knockout: unstimulated versus activated. MSigDB C7: Immunologic Signatures (v6.0) 1.53E-03 1.00E+00 1.38E-02 1.37E-01 47 198 "KLRC4,ADRB2,SPARCL1,GAS7,RGS9,BCL7A,SYNGR3,CACNA2D2,ADGRG1,FEZ1,HDAC9,DBN1,ZEB2,DLG3,ATP8A1,B3GAT1,FYN,DKK3,LYVE1,GYG1,IL12A,ITGAM,KLRC3,MATK,MYO6,PCDH9,PDE4A,CDK14,ABCB1,PTPRB,FAT4,GTDC1,NUDT11,C12orf49,SYBU,SLC1A7,PALLD,ARHGAP26,COLGALT2,ST5,GSE1,MTCL1,SEMA4A,DNMBP,TCF4,TGFBR3,MVB12B" Coexpression M8347 Genes up-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.53E-03 1.00E+00 1.38E-02 1.37E-01 47 198 "NR0B1,MAP7,LARGE1,RCBTB2,FAM149A,AKAP6,VCAN,USP6NL,DOCK4,PLPPR4,DNM2,ELAVL4,OLIG2,SIRPB1,TESK2,GTF2IRD2,FOXF2,NR3C1,IRAK3,PACRG,NCF2,NRCAM,OLR1,OPCML,PCSK5,PFKFB3,SERPINI1,POU3F2,MINDY2,PKN2,RASA3,MYT1L,SOX5,SP4,CLUAP1,PEG10,SPTAN1,TSPYL2,RGL1,AJAP1,MLC1,ZFR2,SIN3B,DMXL2,AHCYL2,TNFRSF1B,FXR1" Coexpression M8003 Genes down-regulated in bone marrow-derived macrophages treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.53E-03 1.00E+00 1.38E-02 1.37E-01 47 198 "RNF157,ADORA3,KCNAB2,ZFYVE28,ASGR1,RGS9,OSGIN2,CD86,ANKRD35,TRIM69,FAM169A,SPATA2,RCAN2,F5,PRKAG2,AGAP3,IQCG,IQGAP2,RNPS1,GLDC,GRK4,PTGDR2,GAREM2,KIF5C,MYO5A,BEX5,TBC1D25,KCTD15,JAKMIP1,PTPN13,RADX,GTDC1,RNH1,PAQR6,SEMA6D,IL17RB,KIF21A,TRERF1,SUPT5H,DOCK9,ARHGEF12,NACC2,FAM124A,CADM1,ANKS1B,EVI5,FZD3" Coexpression M5016 Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7. MSigDB C7: Immunologic Signatures (v6.0) 1.53E-03 1.00E+00 1.38E-02 1.37E-01 47 198 "BRAP,SRPX,ANK2,FGD2,ASGR1,MTMR9,BCL7A,SGCE,EPS15L1,STOML1,CST3,AK5,DRD1,FIS1,GOLT1B,ACTL6B,FOXF2,GABRA1,GPR75,OS9,GSTM5,KCNA2,KCNJ5,NUMA1,OGDH,ENPP2,SMOX,SCHIP1,PLPPR1,RIPOR1,ZDHHC14,RPS6KA2,SAFB,SMPD3,SH3BP2,DHX30,RAP1GAP2,CLASP2,ACSBG1,SMG6,MTMR14,BEX4,TPM4,CHST5,AMACR,GDPD5,KCNAB1" Coexpression M12138 Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion . MSigDB C2: CGP Curated Gene Sets (v6.0) 1.54E-03 1.00E+00 1.39E-02 1.38E-01 39 157 "APP,DDR1,CH25H,HOMER3,CREM,CRHBP,VCAN,SIRPA,ARMCX2,EEF1A2,RASGRP1,TLR7,TPK1,LILRA1,LILRA2,IRAK3,VSIG4,IFI16,CD200,NRCAM,OLR1,PALM,ENPP2,PLTP,MAPK3,BAALC,PLPPR3,ATXN1,IL17RB,SCG5,SLC1A3,SLC2A5,SPTAN1,TCF7L2,TIAM1,TNNT1,SSBP2,UCHL1,NETO2" Coexpression M1822 "Genes important for early anral follicle, based on mouse models with female fertility defects." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.54E-03 1.00E+00 1.39E-02 1.38E-01 7 13 "PCYT1B,SH2B1,IGF1,NOS1,DDR2,NR2C2,UBE3A" Coexpression M5329 Genes positively correlated with amplifications of MYCL1 [GeneID=4610] in SCLC (small cell lung cancer) cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.54E-03 1.00E+00 1.39E-02 1.38E-01 7 13 "CDK5R1,CNRIP1,HPCAL4,KCND2,NELL2,NDRG4,FAM13C" Coexpression M2691 Genes down-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of ATM [Gene ID=472] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.56E-03 1.00E+00 1.40E-02 1.39E-01 37 147 "ARSF,CLCN4,SLC24A2,CYBB,DNAH9,EDN3,SRPK3,STX2,TLR7,FER,PPARGC1A,LILRA2,GPR22,RAPGEF4,GRIN2D,GRM8,IL1RAPL1,AP4S1,ITPKA,MAG,MDFI,MIA2,NEUROD1,NNAT,NTRK2,SETD4,OPCML,NLGN3,GPSM2,PLCD1,PLXNB1,RDX,KCNIP2,MRAS,PCDHB3,TEK,TLL2" Coexpression 15755900-Table2 Mouse Leukemia_Wang05_59genes GeneSigDB 1.56E-03 1.00E+00 1.40E-02 1.39E-01 17 52 "MTUS1,ADGRG1,LY86,GDA,CSF2RA,CTNND1,EBF1,EDNRA,BSCL2,CALCRL,IGSF6,MEIS1,NRGN,PDE2A,SATB1,TGFBR3,TLR4" Coexpression M8285 Genes down-regulated in peritoneal cavity B lymphocytes: wildtype versus lupus susceptibility locus Sle2c1. MSigDB C7: Immunologic Signatures (v6.0) 1.56E-03 1.00E+00 1.40E-02 1.39E-01 46 193 "RNF150,AMH,AMPD2,ASCL1,MTMR2,LURAP1,CAMK2A,IQCK,SLC45A1,KIF19,FARSB,EFNA3,ELAVL3,EMX2,LRRC17,TMEM132C,CSPG5,MEGF11,DISC1,HNMT,CFAP126,KCND2,KCNJ3,KCNK1,KCNQ3,MATN3,MTTP,PDE1A,FAM216A,PTPRD,KHDRBS2,ARMC5,TMEM200C,ARHGEF40,SSTR2,SSPO,STAC2,ABCC8,TCF7L2,PCDHGB7,PCDHB7,RNF175,VSNL1,CLIP2,PCDH20,NAV3" Coexpression M2682 Genes up-regulated in myometrial cells over-expressing a shortened splice form of ATF2 [Gene ID=1386] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.56E-03 1.00E+00 1.40E-02 1.39E-01 46 193 "ADRB2,ABCD2,APAF1,ARNTL,ATP2B2,B3GALT2,RGS11,INA,SYNGR3,ARHGAP22,LHX2,NRXN3,ZNF804A,RASGRP1,LRRC17,FOXG1,FOXM1,PCSK1N,GPER1,GSTT2,FAM107A,SCIN,KCNB1,N6AMT1,MYO7A,NEFM,NNAT,MBOAT7,FSD1,CEP41,RELN,FAT4,BAALC,TMEM156,ASIC4,IL17RB,MRAS,SH3BGR,NLGN1,ABLIM3,ZFR2,SATB2,TRPM2,SLC13A3,SSPN,LAS1L" Coexpression M6511 Genes down-regulated in monocyte-derived dendritic cells: LPS versus vehicle. MSigDB C7: Immunologic Signatures (v6.0) 1.56E-03 1.00E+00 1.40E-02 1.39E-01 46 193 "SNX30,ARHGDIA,ATP1A3,CFLAR,PRC1,RCBTB2,LRIG1,MICAL2,PPP1R16B,TOX,LPAR6,KATNAL1,KIAA1109,FYN,NEK6,NCKAP1,IQGAP2,GLUL,GNAO1,NR3C1,MYO5A,NF1,OGDH,PDE1B,PPP2R5C,PTPN13,GTDC1,CCDC112,ATXN1,CCDC92,ST8SIA1,SLA,CPEB4,TRERF1,KIF1B,RAP1GAP2,TROVE2,SYT11,CAMTA1,FBXW11,SYNE1,TGFBR3,ZBTB16,WNK1,PCBP4,NLRP3" Coexpression M2434 "Transcripts dependent upon IRS1 and IRS2 [GeneID=3667, 8660] for normal expression in liver." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.59E-03 1.00E+00 1.43E-02 1.42E-01 27 98 "ARHGAP5,SCARB1,NIPBL,RBM39,PITPNC1,RCAN1,GNE,SGK2,TAOK3,FDFT1,GCK,GFRA1,PPARGC1A,GK,RND1,HMGCR,HSP90AA1,IGFBP1,IL6R,LSS,MXI1,CDIP1,PPP3CA,ATXN2,SYT1,TNFRSF1B,PCBP4" Coexpression M12001 Cluster 5 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.62E-03 1.00E+00 1.45E-02 1.44E-01 21 70 "RALGAPA1,PKP4,ZSCAN18,ASIC3,SEZ6L2,EFS,SYT17,SLC25A23,SMIM7,CDIP1,ARID4A,SMARCA4,KDM4B,ADGRL3,SIN3B,ZNF34,TSN,PLPPR2,ZFP37,ZNF177,CA10" Coexpression M5823 "Genes up-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 1 h time point that were not up-regulated at the previous time point, 30 min." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.63E-03 1.00E+00 1.45E-02 1.44E-01 19 61 "ATP2B2,CLGN,RASGRP1,SEMA3D,FGFR3,AFF2,FUT9,GRIA1,HLF,IL6ST,KLHL23,PMP2,RET,STUM,SLC6A1,SOX5,AGTPBP1,TLL2,PCBP4" Coexpression 16546165-table2 Mouse StemCell_Williams06_75genes GeneSigDB 1.63E-03 1.00E+00 1.45E-02 1.44E-01 19 61 "PCDH10,ARHGDIA,ATP1A2,DDR1,CALM1,NRXN2,PPP1R1B,CSDC2,GNAS,HPCA,LRRC4B,MBP,PTOV1,PKM,PLP1,BCAN,ATP6V0E2,NDRG4,ITM2C" Coexpression 18450603-Table3S Human Leukemia_Marcucci08_696genes GeneSigDB 1.63E-03 1.00E+00 1.46E-02 1.45E-01 105 515 "ABR,ACTN1,BRAP,KIAA1211,AK2,ALCAM,ALS2,PDXK,ARRB2,ASPH,NUMB,ATM,BID,RAB29,CAST,HIP1R,CD86,MS4A7,CLU,TPP1,QKI,IFFO1,PNKD,CSF1R,CSF2RA,CSF3R,VCAN,CST3,UBXN2A,CYBB,SIRPA,PDCD6IP,ABCC5,EPB41L2,SLC43A2,IGSF6,PRAM1,DLC1,FCGR1A,FGR,PRKAG2,ATP5PD,SEC23B,IP6K2,TMEM107,TPK1,NPTN,NEK6,USP19,GK,LILRB4,LILRA2,MFSD2A,SLC2A6,IRAK3,HMGB1,HNMT,AGFG1,IL6R,INPP1,PIK3AP1,MEF2C,MSR1,NCF2,P2RX7,PCMT1,SNX10,PKM,PILRA,DRAM2,SLC26A11,RIPOR1,MARCH1,RALGDS,HKR1,RNH1,CYB561D1,ACER3,EMID1,RXRA,AP1AR,SARS,ATXN7,ST3GAL3,SLC2A5,SLC11A1,SLC14A1,CAMTA2,THSD1,EPB41L3,FGD4,SEMA4A,TCF4,DMXL2,TCF7L2,TPCN2,AKNA,ARHGAP9,SIK3,FAM200B,TLR4,NPL,VAV1,NUP214,NETO2" Coexpression M473 Genes up-regulated in L929 cells (fibroblast): control versus stimulated with IFN-b. MSigDB C7: Immunologic Signatures (v6.0) 1.64E-03 1.00E+00 1.47E-02 1.46E-01 28 103 "CDC42BPA,SLC4A4,JAM2,AKAP6,CP,ACY3,MED12L,AHCYL1,GNAL,VSIG4,XRRA1,NFYA,CDK14,SERPINE2,PMP2,RANBP3L,RAD51D,RFX5,BAALC,LGR4,KIF27,ZFP30,FAM81A,KDM4D,TRERF1,DDN,SULF2,MRPL47" Coexpression M16591 Genes with promoters bound by HOXC6 [GeneID=3223] in LNCaP cells (prostate cancer) and up-regulated upon loss of function (LOF) of HOXC6. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.65E-03 1.00E+00 1.47E-02 1.46E-01 6 10 "BMP7,SEPT7,SIPA1L1,PDE4DIP,IRAK4,SLC1A3" Coexpression M9752 Genes up-regulated in metastatic vs non-metastatic HNSCC (head and neck squamous cell carcinoma) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.65E-03 1.00E+00 1.47E-02 1.46E-01 74 343 "MTA3,GPRASP2,EP400,PKP4,APBA2,GAS7,ALS2,MPDZ,SLC25A14,TIGD7,FAM19A5,BOC,DNAL1,YTHDC1,MFAP3L,MAGI2,E2F6,ABI2,ASB3,LRRC23,RASL12,ARMCX1,AMZ2,KAT8,SLC37A3,STAG2,ZMYND11,TUBGCP4,GGT7,COPS8,GNAS,GPR19,RASSF8,USP51,AGFG1,DHX35,METTL21A,LAMA2,MEST,ZNF92,BEX5,SLC11A2,DDR2,C11orf49,RETREG2,RAD17,RBBP6,TMLHE,YY1AP1,ELP2,RPE,CDK5RAP3,MTERF2,EFHD1,TTC17,SNRPN,SPATA7,EMC1,CAND2,BEX1,ZNF621,ZFP90,BHLHB9,BEX4,TP53BP1,CADM1,ZBTB14,ZNF711,ZNF24,ZSCAN26,MFF,LMAN2L,ADAMTS9,FIP1L1" Coexpression 21169407-TableS2 Human StemCell_Shats10_100genes_InducedPluripotent GeneSigDB 1.65E-03 1.00E+00 1.47E-02 1.46E-01 24 84 "AMT,MAP7,CDO1,CNTNAP2,PPP1R16B,DAPK1,RABGAP1L,AASS,PIPOX,CELF1,GLDC,TOX3,GPM6B,PSIP1,TUBB2B,KIF5C,MYCN,PPM1E,SEPHS1,SOX2,COBL,LEFTY2,HEY2,UGT8" Coexpression M2488 Genes down-regulated in HeLa cells (cervical carcinoma) upon knockdown of PHF8 [GeneID=23133] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.68E-03 1.00E+00 1.49E-02 1.48E-01 152 784 "ADRA1B,MTA3,PKP4,TMEM263,CASK,EIF4G3,STX16,MTMR9,BTRC,CALM1,CANX,CAST,REPS2,IGFN1,ZBED5,FAM189A2,ABCG2,TMEM184B,IFFO1,TOGARAM2,C2CD2,AKAP12,MICAL2,OSBPL3,CTNND1,GPSM1,HDAC4,SCRN1,SPOCK2,PLEKHM1,RABGAP1L,ARNT2,DPYSL2,DNAJB6,SNX29,EDN1,OPTN,APH1A,EBI3,ABI2,TNK2,C3orf18,EML1,DCTN4,ENO2,EPB41L1,SPEG,TAOK3,FER,FGF13,BAIAP2,TMEM164,SCARA3,ANKFY1,TACC2,STAMBP,TPK1,RASL10A,CELF1,DKK3,DENND2A,ZMYND11,SYT17,SPIN1,PRRC2B,KIF3A,COQ10A,TMEM25,SYNPO,LRRC75A,IDH3A,LINC00667,LSS,MATN2,MBNL1,NRBP2,MYO9A,NAP1L1,NCF2,NFIA,OCRL,OPHN1,PBX1,PDPK1,PFKFB4,ZNF655,CCSER2,RETREG1,PLEC,LRP12,FSD1,TATDN3,PPP2R2B,FITM2,SAMD9,DEF8,PLEKHB2,SH3TC2,RAP1GDS1,RGS3,KCTD17,RPRD1A,KIRREL1,ROM1,PCMTD2,TCP11L1,PAQR6,ASRGL1,MYO18A,ST6GAL1,SLC12A4,ELMO2,CPEB4,MAPKBP1,ZHX3,ERC1,KIF1B,CLASP2,NXT2,VPS13A,ATP11A,TACC1,MTCL1,MGRN1,SIN3B,USP22,AP4E1,TGFBR3,TLR4,ERCC6L2,KCTD2,TNNT1,TPD52,RGMB,TMPRSS5,TST,OSBP2,TOM1L2,LAT2,NDRG4,CELF4,POLR3H,DPYSL5,SYNC,MAP3K12,GDPD5,SEMA3B,NAV2,PPP1R3F,C12orf4,FRMD6,SENP7" Coexpression M1873 Genes down-regulated in bone marrow progenitors by constitutively active NOTCH1 [GeneID=4851]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.68E-03 1.00E+00 1.49E-02 1.48E-01 9 20 "BTK,CSF1R,CSF2RA,CSF3R,LRRC25,ITGAM,MATK,NCF2,TREM2" Coexpression 16778177-Table3 Human Brain_Wang06_79genes GeneSigDB 1.69E-03 1.00E+00 1.50E-02 1.49E-01 16 48 "EIF4G3,ADGRB2,KALRN,CDC42,CHD5,SDC3,PUM1,SRRM1,HMGCL,STMN1,PIK3CD,SCNN1D,CLSTN1,CAMTA1,TNFRSF1B,PRDM2" Coexpression 18537973-SuppTable1b Human Lymphoma_Miyazaki08_70genes GeneSigDB 1.69E-03 1.00E+00 1.50E-02 1.49E-01 16 48 "GPR158,DDO,PDE8B,CABP7,TIAM2,RASL10A,SYT17,LMO2,LSS,MGAT3,OGG1,GRAMD1C,PXK,RAP1GAP,KDM3A,SSTR2" Coexpression M7779 Genes down-regulated in macrophages: untreated versus 48h after M. bovis BCG infection. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "ADGRB1,BBS2,NRP2,OSGIN2,BAIAP3,CACNB4,FBXO7,COL9A3,MAGED1,CLOCK,ABCG1,LRIG1,INTS1,CPEB2,DYRK1A,FRY,EIF4G2,FGFR1,NCKAP1,STARD10,DCLK2,CECR2,HPS5,SCIN,IL6R,KIT,L1CAM,LAMP2,LSAMP,PPM1L,PDCD2,PTCH1,BEND5,ADAL,FOXRED1,SLC1A7,PDZRN3,SPTAN1,POGZ,STX1A,SLC37A2,TAL1,RGMB,UBC,WRN,SLC26A10,CBLN2" Coexpression M5344 Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "APAF1,CAPRIN2,ATM,DPY19L3,USP6,CCPG1,CREB5,ANKRD44,NCOR1,CSNK1G3,KIAA0040,CX3CR1,DBI,FBXL5,C2CD2L,HIPK3,MRVI1,FCGRT,FDFT1,FYB1,GAA,GAB1,MSL3,TUBA1C,NCKAP1L,INPP5B,JAK2,PTOV1,ZNF92,NASP,NF1,NRDC,GRAMD1C,DEF8,ZYG11B,RMI1,SLC8A1,TRERF1,RAP1GAP2,NSFL1C,SIN3B,ARHGAP9,TPM3,TSC1,INTS3,EVI5,MPPE1" Coexpression M5083 Genes up-regulated in comparison of memory CD8 T cells versus those treated with IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "GPRIN1,CCDC85A,PCDH19,LRFN1,KALRN,RAB3C,NRXN2,FAM149A,CREB5,RUSC2,TRAPPC9,DTNB,LINC00599,ELN,COQ7,OLFM1,SYT3,GABRA2,GABRG2,DENND2A,ATF7,CCDC184,GRIA1,NKD1,KLRC3,SCAMP5,NELL2,PDGFRA,PLCD1,PMP22,POU3F4,MDGA2,LGI2,RPE65,BAALC,SCN2B,ABLIM3,EPC1,SPATA7,TSNAXIP1,SST,KAZN,TNNT1,IL34,TTPA,ZNF213,UBE3B" Coexpression M4429 Genes down-regulated in comparison of naive CD8 T cells versus naive B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "APP,SLC4A4,ATP6V0A1,BCL2L2,BCL7A,BTK,DDR1,USP2,REPS2,LARGE1,CLCN4,LY86,CNR1,HDAC9,ARHGAP32,SNX29,HEYL,RASL12,CORO2B,RASL10A,GABBR1,CHL1,GATM,RAB30,GPM6A,IRF8,MEF2C,MID1,CD200,CDK14,STRN3,POU6F1,MTMR10,RIPOR1,ZNF532,CNKSR2,SLC2A5,IDI2-AS1,PEG10,CDK19,ATP11A,DNMBP,ACSL6,TCF4,PCDHGA10,VAV2,DPF3" Coexpression M7920 Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG and TNF [GeneID=3458;7124]. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "SLITRK1,PHYHD1,SHTN1,LGR5,KIF1A,ADGRB1,SCAPER,RAB29,PRC1,LONRF2,GALNT9,ERC2,KIF26A,MFAP3L,RAB39B,CDHR1,SUCO,SDCBP2,HRASLS5,LNX1,PSRC1,NXPH3,ITGA7,MYH6,PCSK1,PILRA,PPP1R1A,PRKAB2,PRKACB,RASGRF1,LRFN5,BCAN,NUBPL,LRRC4,TAL1,UNC5D,AHCYL2,FBXL16,THRA,NACC2,TTC3,AMZ1,PLPPR5,SLC30A4,GDPD5,SCG2,SENP7" Coexpression M9739 Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus Ly6c int CXCR5+ [GeneID=643] memory. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "NDRG2,ADD3,DGKD,TNRC6C,SPTBN4,HIP1R,CD38,RCHY1,SNCAIP,CSF1R,RASSF2,GIT2,ELMSAN1,GUCD1,RASGRP1,ING4,RCSD1,TMEM151A,INPP5K,SESN1,GPR34,IL6R,AQP11,MXI1,P2RY13,NUMA1,PDE2A,RETREG1,PLEC,PURG,SPATA6,POU6F1,MINDY2,PPP3CA,PRPH,PTPRO,C1orf54,CCDC82,TACC1,TCF7,SLC44A1,BEST1,LAT2,EVI5,MSRB3,ADAMTS10,PIANP" Coexpression M8496 Genes down-regulated in B16 melanoma (day 7): untreated versus adoptive transfer therapy. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "RNF150,GOLGA7B,PPFIA4,KIAA1614,ALDH4A1,ATP1A2,DIRAS1,CDH10,EVI5L,FADS2,CNTFR,MAGED1,LRRC3B,CNTNAP2,CMTM5,AIF1L,DCC,ARMCX2,SLC29A4,DNM2,ELN,STARD3NL,LRRC23,SEMA6C,FYN,GLI2,NCKAP1L,LIX1,GATD1,PTOV1,RTL5,PDE4A,FXYD1,NECAB2,ZDHHC14,ASIC4,SH3GL3,ST6GAL1,RPH3A,LIMCH1,DNMBP,TCF7,ARHGEF12,CRTC1,SLC30A4,FBXO36,PRRT4" Coexpression M8473 Genes up-regulated in splenic B lymphocytes: wildtype versus KLF3 [GeneID=51274] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "ACADM,AXIN2,HHATL,KLHL13,ASTN1,ATP1A2,CACNA2D2,KIAA1549L,CNR1,CNTFR,PHF14,DNAJC6,RGS17,RCAN2,CAP2,ATP8A2,STARD10,GCK,MFSD2A,VSIG4,KCNJ3,MAOB,JAKMIP3,ADAM22,OGDH,ING3,PPARA,PRKAB2,PKIA,PTN,RGS12,PCMTD2,ARMH4,SGSM1,PAQR6,ST6GALNAC6,RYR1,PRCD,FOXRED1,SUPT20H,SCG5,RCOR3,PDZRN3,NECAB1,KLHL4,SIN3B,CELF4" Coexpression M4404 Genes down-regulated in comparison of naive CD8 T cells versus naive CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "MRTFA,ANK1,APP,CAPRIN2,ATP1A1,CADM3,CACNA1I,ARHGEF1,ENTPD4,SH2B1,CRYM,INTS1,FAM13A,SORBS3,RASGRP2,MTSS1L,F5,REEP2,FOLR2,SORBS1,FUT9,GABBR1,DENND2A,GFAP,CLASRP,HTR5A,MAPT,MXI1,OXTR,PALM,PILRA,PTK2,C1orf54,LGI2,SUGCT,ATXN7,FUZ,HKDC1,SLC6A8,ATP11A,TACR1,TNS2,TIAM1,PRMT8,GORASP1,WNT7A,SEMA3B" Coexpression M5420 Genes up-regulated in comparison of eosinophils versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "TTYH1,FAM131A,CDC14B,MARCH3,CACNA1B,CALM1,CCNH,REPS2,SLC4A8,USP6NL,PLXNC1,OLIG2,RTN3,TLR7,TAOK3,SEMA6C,GLRB,GRB10,C2orf72,RBPJ,INPP1,ITPKB,JAK2,THYN1,FXYD1,PRODH,PTH1R,PTX3,RERGL,DCUN1D2,LGR4,RXRA,TMEM156,SEC14L1,SGK1,ITSN1,FAM102A,SLA,RUFY2,RAB3GAP1,BTBD7,MAST1,ARHGAP26,ITPRID2,ACSBG1,USP22,UBE2H" Coexpression M4167 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "ADCY5,GOLGA7B,GPRASP2,BIN1,LINC00173,ST3GAL5,CFL2,MAP4K4,PNPLA8,PITPNC1,KLHL3,AK5,NR1D2,SNX29,MBNL2,KCTD3,TENM1,RASGRP2,GTF2IRD2,GABBR1,IL11RA,MXI1,LYRM9,PCSK5,PDE2A,PDE4D,PNMA3,DRAM2,MINDY2,PPP3CA,PPP3CC,ZNF844,SUSD4,TRAPPC13,TMEM156,FNIP1,HKDC1,GKAP1,RAP1GAP2,AGTPBP1,TCF7L2,FAM200B,ZNF34,TPM2,MICAL1,ZNF711,CERS6" Coexpression M5215 Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "ASIC2,ARID1A,APC,N4BP2L1,NRP2,CFLAR,MYRF,CAMK2A,CAMK2B,CBARP,COL4A5,COL9A2,COL9A3,FAM131B,DGKB,MAGI2,DNAJB6,SNX29,ENO2,LRRC23,REEP2,TUBB4A,AFF2,B4GALNT1,GLDC,FERMT2,RAPGEF4,PTPRT,GUCY1B1,DIPK1A,ADAM11,CD200,PLCL1,PMP22,POU6F1,PSMA6,ITSN1,FAM102A,SLC1A2,SLC12A2,SNAP25,SYN1,SYT1,TIAM1,TIE1,CADM1,TRIM9" Coexpression M3460 Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "ACTN1,MTUS1,AMPH,BIN1,APBA2,DGKZ,DNAH17,STX16,SLC2A11,DLGAP1,DSCAM,EEF1D,EFNA2,PCOLCE2,ATP8A1,RACK1,KIAA1109,AGAP2,SEMA4D,GAD2,ERAP1,SEPT9,GPR162,PRRC2B,PCLO,GRB10,BTN2A1,HPR,IL11RA,KCNK3,KTN1,PDE4B,MORC4,RFX2,PCMTD2,TMEM156,ASAP3,CLUAP1,NSFL1C,AHCYL2,SIK3,NACC2,NR2E1,RIMBP2,TPM2,ZMYND8,SLC17A6" Coexpression M5295 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 1.71E-03 1.00E+00 1.50E-02 1.49E-01 47 199 "RALGAPA1,NDRG3,ADD3,KIAA1324,BIN1,DGKD,THSD7A,CBFA2T2,CHI3L2,ARHGEF6,AKAP7,TCEAL2,RIPOR2,TBC1D5,PITPNC1,KLHL3,USP3,DOCK2,RASGRP2,EYA1,FCGRT,FYB1,GNAO1,GRIN1,IL11RA,KCNH2,MSRA,MXI1,NELL2,NF1,NFYA,PCBP3,NUCB2,PDE4D,ENPP2,PLCD1,PRKCB,ZNF331,TNIK,MYCBP2,RAP1GAP2,MCF2L,SSBP2,WNT7A,ZNF711,MARCH8,NLRP3" Coexpression 19038878-SuppTable3 Human Leukemia_Lenz08_385genes GeneSigDB 1.72E-03 1.00E+00 1.51E-02 1.50E-01 75 349 "ACTN1,ZNF608,MTUS1,TBC1D14,ADGRF5,SPARCL1,APOC1,APP,IGDCC4,DST,CACNA2D1,CHN1,CLU,PCYT1B,ABI3BP,ZNF521,CNRIP1,CSF2RA,MICAL2,VCAN,CTNND1,HEPH,DNM1,ARRDC4,EDIL3,EDNRA,KLHL5,CERCAM,EML1,RASL12,KATNAL1,ZNF585B,DLC1,SCARA3,SORBS1,NEK6,GHR,GNAL,FERMT2,GRB10,PARD3B,GSN,ITGAV,ITPKB,TTYH2,LAMP2,LMO2,KITLG,MITF,CCDC80,PLIN1,PCDH18,PMP22,LRP12,PRRX1,PTK2,PTPRB,ROBO1,WLS,RTN1,DZIP1,ZCCHC24,UNC5B,EPB41L3,ST5,AZIN2,OBSL1,ZFPM2,DAAM2,TPM1,SSBP2,PMEPA1,NAV2,MSRB3,FRMD6" Coexpression 18425577-TableS3a Human Breast_Creighton09_594genes GeneSigDB 1.73E-03 1.00E+00 1.51E-02 1.50E-01 92 443 "ABAT,BRAP,APBB2,BCAS1,CHRD,CA12,CACNA1D,CAMK2B,NFS1,LRBA,REPS2,LRRFIP1,CACNA2D2,RAB26,IQCK,COL4A5,LRIG1,KIAA0040,GREB1,CTNND2,GAPVD1,YTHDC1,FBXL5,EEF1A2,FRY,KMT5B,KCTD3,LRRC17,ERBB4,GMPR2,CHST15,ZMYND10,BAIAP2,CAP2,EVL,NBEA,STAU2,ATP8A2,TUBGCP4,GFRA1,HPGDS,GLUL,GOLGB1,ELOVL5,HMGCL,IL6ST,KCND3,KCNJ3,MAPT,MATN3,NOVA1,RETREG1,STRN3,SYTL2,SIDT1,ELOVL2,ZSCAN32,NKAIN1,RAD17,ROGDI,RET,ZC3H14,STK32B,GALNT10,CPEB3,SYBU,PAAF1,ABLIM3,IFT122,KDM4B,GLT8D1,DBNDD2,CLSTN2,LARP4,ABCC8,SYT1,TNS2,FRYL,TNNT1,UBE3A,DNAJC12,MEAF6,LMF1,NPDC1,ZNF24,REEP1,MAP3K12,DNALI1,LMAN2L,SEMA3B,MARCH8,IFT88" Coexpression M6863 Genes up-regulated during B lymphocyte differentiation: pre-B I versus large pre-B II. MSigDB C7: Immunologic Signatures (v6.0) 1.74E-03 1.00E+00 1.53E-02 1.52E-01 39 158 "ABHD6,ACTN1,FMNL2,HECW2,TAOK1,CDC42BPA,SFMBT2,ARHGAP5,HCN2,DST,OSGIN2,HAP1,MAGED1,ANKRD44,RABGAP1L,ABI1,DTNB,EDNRB,RASGRP1,RPS6KC1,TAOK3,STAU2,TPPP3,STAG2,HTR2A,HECTD2,GPR85,PTCH1,SATB1,MRAS,GKAP1,SCN3B,SP2,SYNE2,ARHGEF12,CRB1,TTC3,SLC30A4,NETO2" Coexpression M6805 Genes up-regulated in B lymphocytes expressing IgM - BCR [GeneID=613]: untreated versus anti-HEL. MSigDB C7: Immunologic Signatures (v6.0) 1.76E-03 1.00E+00 1.54E-02 1.53E-01 32 123 "TKTL1,PLEKHG5,AP2A2,DPP10,TTLL9,IL33,TCAF1,ARHGAP24,MFAP3L,EMX2,DNAJC27,GALR1,NUDT21,PLPP7,LINGO1,SCIN,KCNK2,ALDH1L2,FSD1,SBF1,CTXN2,LRRC55,KDM4D,STAC2,STX1A,TMEM121,RUSC1,CLIP2,PLPP4,MEIS3,GAN,FAM198A" Coexpression 16498405-TableS5 Mouse Kidney_Takemoto06_177genes_cat3 GeneSigDB 1.76E-03 1.00E+00 1.54E-02 1.53E-01 32 123 "C1QTNF1,ADGRF5,THSD7A,LDB2,LRRFIP1,SNCAIP,COPS7A,MAGI2,EDNRB,OPTN,PLEKHO1,GABRA4,PCDH17,PARD3B,SYNPO,MAPT,MEIS2,MEST,NAP1L1,SERPINE2,SERPINI1,SCHIP1,PTPRO,ROBO2,GALNT10,PALLD,DDN,TMEM150C,DAAM2,UBC,CRB2,RTN4" Coexpression M8123 "Genes down-regulated in ZR-75-1 cells (breast cancer, amplified 8p11-12 region) upon knockdown of PPAPDC1B [GeneID=84513] by RNAi." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.80E-03 1.00E+00 1.57E-02 1.56E-01 18 57 "ADD3,SYT13,DPY19L3,CALM1,HDAC4,RCAN1,GPR153,GLDC,HSD17B1,IL6ST,KIF5C,MXI1,PTPRG,RAP1GAP,SUSD4,SH3BP2,IFT122,TMCC1" Coexpression 15940248-SuppTable2 Human Uterine_Vanharanta05_107genes GeneSigDB 1.87E-03 1.00E+00 1.57E-02 1.56E-01 27 99 "OSBPL1A,APBB2,BCS1L,AKAP6,TBPL1,NCOR1,GAPVD1,ING4,EFS,GAA,PRUNE2,EML4,IFI16,NAP1L3,PCMT1,PDE3B,GON4L,TMEM231,RBBP6,UBR7,NEK11,FBXO11,SMARCA4,TCEA1,PSD3,TMPO,CADM1" Coexpression M8928 Genes down-regulated in CD4 [GeneID=920] naïve versus Th17 enriched. MSigDB C7: Immunologic Signatures (v6.0) 1.89E-03 1.00E+00 1.57E-02 1.56E-01 42 174 "ADCY6,ZBTB10,CD38,CLTC,DAPK1,RABGAP1L,ABI1,TOM1,DNM1L,EBF1,EIF5,TMEM35A,ACSL4,MPP6,GSTT2,ADAMTS6,ACOT7,TJAP1,IPO5,PIK3AP1,MYO9A,RETREG1,STRN3,SPATA6,PPP3CA,C1orf54,SLC25A36,ZC3H14,SLA,SMARCE1,FNBP1,TEX2,SAMSN1,LARP4,ERBIN,SYPL1,TCF4,MTMR14,RUNDC3B,TUBB2A,PLD4,SENP7" Coexpression 12175522-table1 Human Prostate_Wang02_25genes GeneSigDB 1.90E-03 1.00E+00 1.57E-02 1.56E-01 10 24 "AK2,ATM,DDR1,DCLK1,PDGFRA,PTPRG,PTPRN2,PTPRO,PTPRZ1,SGK1" Coexpression M3941 Genes changed in the B cell chronic lymphocytic leukemia (B-CLL) with deletions in the 13q14 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.90E-03 1.00E+00 1.57E-02 1.56E-01 10 24 "BCL7A,EFNA2,EPB41L2,TUBB4A,TRIM16,PNMA2,TUBGCP4,JAKMIP1,TPM2,SSBP2" Coexpression M7891 "Genes down-regulated in macrophages (12h): control versus IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]." MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "AP2A2,AK2,CCDC146,APP,BARD1,BMPR1B,SUMF2,PHACTR3,ST18,FGFR1OP2,BRINP1,EPB41,EFEMP1,STRADA,POMT1,KBTBD12,GABRB3,GNAL,GPR17,GPR34,ICA1,OLFM3,KCNN2,COMMD5,STK32C,MYH3,LYRM9,NF1,NFIA,PDCD2,PLPPR1,RAB5B,UBR7,SAFB,ZNF334,LIMCH1,MYCBP2,ATP10B,THSD1,ZFP90,WASHC4,KCNE5,RPL7L1,UCHL1,KCNK12,CFAP298,PCBP4" Coexpression M9848 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "KIAA1211,LRFN2,ALCAM,PCDH10,CD38,CDC27,EPS15L1,CRY2,CTNND1,AK5,DNM1L,CACNG7,OPTN,EFNA2,RBM12,EBI3,F3,SEC24B,FGF1,GALR1,GLS,EML4,RFFL,ZHX1,AGFG1,HSP90AA1,KTN1,AFF1,PCDH9,PPM1B,PPP3CC,MAPK8,RPS6KA2,PAQR6,FRMPD1,SLC8A2,SMARCE1,KDM4B,STAU1,CLDND1,ZFAND5,SHD,CIAPIN1,FIP1L1,CERS6,RSPRY1,PRRT4" Coexpression M5773 Genes down-regulated in dendritic cells (DC) from spleen versus those from intestine. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "TMCC3,AP1B1,FAM135A,AMPH,GPAM,MYOM1,BARD1,NEURL1,CLTB,FAM189A2,FADS2,SMARCAL1,IST1,DNAL1,DNAJB6,DNM1L,MRVI1,FCGR1A,BAIAP2,ZMYND15,TMEM107,FYB1,CHL1,GALC,LYVE1,NCOA7,LYPLAL1,SCAMP5,NPY,LRP12,MAPK8,NUDT11,ALG9,KCNIP3,MRAS,CLASP2,PHLDB1,KLHL7,SLC37A2,POPDC3,TCF12,TPM2,VAV2,P2RY12,PORCN,AGMO,PRDM8" Coexpression M6196 Genes down-regulated in polymorphonuclear leukocytes (9h) infection by A. phagocytophilum: heat killed versus live bacteria. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "CDC7,OSBPL1A,CC2D2A,PLA2G6,CASK,SLC4A4,CACNB2,LARGE1,SLIT2,TENM4,USP6NL,DGKG,DNAL1,C8orf34,MFAP3L,DCTN4,EFS,F3,CORO2B,FHL1,GPM6B,DOCK7,LSS,AFF1,SAMD14,NRCAM,OPCML,PDE4D,ENPP2,CAMKV,PIK3CD,GPSM2,ACER3,TRAPPC13,ZFP30,PPM1E,BEX1,DBNDD2,SEPT8,ATP13A2,CDK20,PDSS1,SSBP2,FLRT2,WRN,ZFP41,FZD3" Coexpression M6166 Genes up-regulated in D10.G4.1 T cell line (6h): control versus treated with NMU [GeneID=10874]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "DYNLL1,ATP2B1,CNRIP1,CSNK1E,VCAN,PNPLA8,CTNND1,JAKMIP2,FBXL5,ZC3H11A,USP3,PDCD6IP,MAMLD1,PHC2,SH3GLB1,ACSL4,TAOK3,IP6K2,FLT1,ARFIP1,KLHL23,LAMP2,LIMS1,TM6SF1,NAP1L3,RC3H2,SPATA6,PID1,EPHA10,ATP8B4,WLS,SLC11A1,KIF13A,FAM219A,NXT2,STAU1,STX1A,PJA1,CAMTA1,TCF7L2,ERCC6L2,TMPO,TRIO,TRPS1,LAT2,LINC02210,CAB39L" Coexpression M9278 Genes up-regulated in CD8 T cells 3 days after immunization: control versus IL2 [GeneID=3558] treatment. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ARID1A,APP,ARHGAP5,ATP2B1,BCL7A,CFLAR,DDR1,CFL2,GAL3ST1,LRIG1,KIAA0040,GPRASP1,EARS2,NR1D2,LRRC23,ST3GAL6,SUCO,FOXO3,ZMYND11,GPR34,PADI2,KCNC2,KIF5C,SMAD1,CHIC1,PDE3A,ABCB1,PIK3R1,PPM1B,LRRN3,PID1,TMEM206,MAPK12,GALNT10,SGK1,FAM102A,PEX26,ZFR2,RHBDL3,KIAA0930,PIK3R5,TRH,BEST1,FSTL5,ZSCAN26,MEIS3,FAM219B" Coexpression M8223 Genes up-regulated in Pmel-1 CD8 T cells primed with cognate antigen: IL2 [GeneID=3558] versus IL-12. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADGRF5,TRMT9B,KIF6,AQP6,SLC7A14,PPP4R4,ALDH7A1,KSR1,MTMR2,CAPN3,CHGB,AKAP5,AATK,CALY,ACY3,TMEM130,EGFR,EML1,BRD8,AIFM3,PTPN5,ATCAY,NKD1,KCNF1,LIFR,SMAD9,MAP2,MATN3,NRGN,PMP2,LRRN3,LAMA1,PTCH1,PEX5,C1orf54,PAQR6,ST6GALNAC6,GALNT10,SEPHS1,DBNDD2,RGL1,VAMP1,TACR1,TRH,FSTL5,GJC2,NETO1" Coexpression M9755 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Ly6c int CXCR5+ [GeneID=643] versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ALCAM,CDC14B,PDXK,TMEFF1,CACNA1B,LGI1,JAM2,NGEF,TJP2,CPS1,CRYM,SLC25A18,ATN1,F3,AMZ2,PRELID3A,GAA,MALT1,GNG4,GUCY1B1,TOX2,SYNPO,AGFG1,RBPJ,ITGAV,JAK2,GIT1,PFKP,PMP22,PACSIN1,SH3KBP1,UHRF1BP1,ROGDI,RNH1,RPS6KA2,ST6GALNAC6,PREX2,SPP1,BEX1,ARC,FBXW11,TPD52,TRIO,TRPS1,TUBB2A,LAT2,SLC38A1" Coexpression M3091 Genes down-regulated in comparison of systemic lupus erythematosus B cells versus systemic lupus erythromatosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ARRB2,ASGR1,TJP2,CSF1R,CSF3R,FEZ2,MICAL2,VCAN,CST3,KIAA0513,DAPK1,SIRPA,LPAR6,IGSF6,FCGR1B,ST3GAL6,FCGRT,TMEM164,GAA,GALC,GLUL,LILRA1,LILRA2,HNMT,ITGAM,NCF2,PILRA,PTPRE,C1orf54,ARHGEF10L,RXRA,ARHGEF40,SLC11A1,SLC22A4,ZCCHC24,ARHGAP26,EPB41L3,DMXL2,KIAA0930,TCF7L2,NACC2,TNFRSF1B,TPD52L2,NPL,BEST1,RTN4,NLRP3" Coexpression M9406 Genes up-regulated in CD8A [GeneID=925] dendritic cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ACTN1,ARRB2,ATP1A3,ALDH7A1,BID,PROM1,DST,NAE1,TJP2,MAP4K4,SV2A,KBTBD11,SCML2,ST3GAL6,FHL1,FOXM1,FOXO3,TRAF3IP2,MTHFD2,GART,GLDC,STARD3,ADGRA3,LILRA2,GRB10,NR3C1,CIT,GUCY1A1,LMO2,MATK,MEF2C,NPY,SERPINI1,RETREG1,SCHIP1,SLC2A5,ZNF423,RGL1,PLCB1,COBL,EHBP1,DMXL2,PSD3,AMOT,ATP6V0E2,CERS6,ZNF248" Coexpression M5480 Genes down-regulated in comparison of dendritic cells (DC) versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "BEGAIN,CNTNAP1,DLGAP2,PICK1,AKAP6,SEC14L5,SPOCK2,CTIF,PITPNC1,SMG7,EN2,LINC01278,NRN1,ATF7,LPAR4,DIDO1,GRM1,KCNJ9,KLRC3,MEF2C,NAP1L2,NCAM1,NUCB2,PDE1C,PDE4D,PMP2,PCDHB17P,SIDT1,PTCH1,PTPRD,UBR7,STK32B,NCBP3,SELL,FRMPD1,WDR37,INAVA,MYT1L,NMNAT2,HECW1,TSPYL2,SYNE2,VAMP1,SYNE1,THBS4,TPM3,FTSJ1" Coexpression M4871 Genes down-regulated in comparison of NKT cells versus monocyte macrophages. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ASPHD1,ZNF608,SPOP,BCAR3,ZNF687,AMPD2,VAT1L,GPR146,CACNA1G,NIPA1,CAMK2A,PRC1,CDK11B,CDH10,BOC,RASSF2,OPTN,VPS13B,CACNG2,AMOTL2,TPPP3,TUBA8,GRB10,PARD3B,DOCK7,STXBP5,NAP1L2,NRDC,PLP1,SLC36A4,ZDHHC4,RNASE1,PTGR2,SCP2,COPZ1,HSPA4L,FHOD3,SLC8A2,RADIL,SCMH1,CPEB4,AGTPBP1,TRPM2,VIPR2,KCNK12,SPHK2,NETO2" Coexpression M5153 Genes down-regulated in comparison of dendritic cells (DC) versus DCs exposed to B. malayi (5 worms/well). MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADCYAP1R1,CDC42BPA,PPFIA1,CDK13,ADAM15,ADGRB2,KRIT1,CPNE6,SUSD5,KIAA0586,DTNA,FRY,AASS,TENM1,MTSS1L,CAMSAP1,GAB1,C1QL1,GRM5,KIF3A,PADI2,IRF8,KCND3,KIF5C,MAPT,MDFI,ZNF92,MYL3,PDE1A,PDE4A,PDE4D,PENK,PHKG1,PRKAB2,PTN,PYGM,RAP1GAP,RET,RFX2,RLBP1,ST5,ZFR2,SYN1,OBSL1,TRIO,SF1,UBE3B" Coexpression M7712 Genes up-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ANK1,ARHGAP5,PLA2G4C,NUMB,BACH1,SYNJ1,ST3GAL5,DLGAP2,DNAJB5,CABP1,ARHGEF10,ZFYVE16,SIRPA,SPATA2,CEP170,SACS,SPOCK3,DLG4,GOLT1B,TUBB3,FLT1,USP16,B3GAT1,TBR1,RAPGEF6,ATF7,NR3C1,AGFG1,KCNN3,MATK,NFE2L2,PFKFB3,RXRA,SFPQ,WDR37,BTBD7,IDI2-AS1,ZBTB43,APOM,PRRC2C,ICAM5,TNFRSF1B,TPM4,UBE3A,PORCN,SF1,PRDM2" Coexpression M3821 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 24 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "HACE1,TXNDC16,ARRB1,NUMB,ADAM23,BID,TMEM184B,FEZ2,DCT,MED24,ARNT2,TOM1,SH3GLB1,STX2,FCGR3A,SEC24B,FGF13,AHCYL1,PTGDR2,KIF2A,L1CAM,LAMP2,ADAM11,NKX2-2,TREM2,PFKFB3,PLCB2,PRRX1,SNRK,MTMR10,C1orf54,PRIMA1,RPL38,NCBP3,RASA3,FNDC3A,EPC1,ITPRID2,SEPT8,TCF7L2,SIRT1,TIMP4,TTC3,TUBB2A,WIPF1,LAT2,VPS35L" Coexpression M3614 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SLC25A25,BRAP,NCOA1,SEC11C,FOXK1,CCKBR,USP2,MYOM2,CLTB,AKAP7,ABCG1,NR1D2,ACOT8,E2F5,RASGRP2,ERCC2,TLR7,F3,UBE2E3,USP21,GABBR1,CNTRL,COQ10A,INSM1,KCNH1,KIT,KITLG,MX1,MYL3,PDE4B,PKD1,RC3H2,RETREG2,POLG,PRPSAP2,PYGM,RAB5B,BSDC1,ZYG11B,SCAF8,SP4,ST5,MAPK8IP3,KLHL7,EXOC7,TEK,TSC1" Coexpression M5720 Genes up-regulated in comparison of NK cells versus total splenocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "AS3MT,RNF157,PKP4,ZBTB10,BAIAP3,CHM,PHACTR3,GPSM1,ARMCX2,TSPAN5,ABI2,EYA1,OLFM1,JKAMP,CAB39,IQGAP2,ARFIP1,SPACA9,GSTM5,KLF12,HSPA1L,KIFC3,STXBP5,SMAD1,AFDN,ABCB1,SYTL2,PTPRE,USP47,TRIM68,ERI2,ATP8B4,PRR5L,NTNG1,WDR37,FAM81A,TET1,SMARCD3,SP4,RAP1GAP2,SYT11,SEMA4A,KLHL4,ARHGAP9,GPRIN3,PLSCR4,GAN" Coexpression M9324 Genes up-regulated in marginal zone B cells versus day 40 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "KCTD16,ANXA7,ALS2,ST3GAL5,P2RX6,UBE2L6,FADS2,CDC42BPB,SEC14L5,DBN1,RASA4,LPAR6,CHST15,FCGR3A,OLFM1,KBTBD12,TPPP3,GABBR1,FAM184B,STARD3,NXPH3,LMO2,MYO9A,RTL5,GNG2,PKD1,PLCL1,PRKAB2,RAB39A,MAPK7,MTMR10,ROGDI,ARID4A,KIAA0895L,RPS6KA2,SCN2B,ST6GAL1,FAM214B,SCN3B,C3orf70,ARC,ATMIN,UBC,VAV2,ZNF23,MAP3K12,PLD4" Coexpression M6964 Genes down-regulated in plasmacytoid dendritic cells in response to influenza virus infection: 1h versus 4h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "GPR158,TAOK1,HCN2,CLCN3,GAL3ST1,CSF1R,IPCEF1,CTNND2,GPSM1,DNAJC6,KBTBD11,EBF1,MRVI1,CHST15,SEMA4D,TACC2,CAMKK2,TRAF3IP2,PTGDR2,BACH2,LRRC75A,PIK3AP1,NAT8L,MN1,HCN1,NUCB2,PCDH9,CAMKV,MED1,PRKCB,TTC13,ATP8B4,SATB1,ATXN2,ST8SIA1,DHX30,LGI3,TET1,RBM26,RHBDL3,SEMA4A,TCF4,KIAA0930,AKNA,CYB561A3,FBXL16,WNK1" Coexpression M5818 Genes down-regulated in comparison of wild type macrophage treated with LPS (TLR4 agonist) at 4 h versus those from IRAK4 [GeneID=51135] deficient mice treated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SNX30,AP2A2,TBC1D14,OSBPL6,PLA2G6,AQP6,CHID1,ARHGEF7,CAMK2G,CERS5,RCBTB2,NGEF,FAM189A2,FADS2,CST3,RASSF2,CCDC3,FABP7,TUBA1B,EFEMP1,SARAF,NKX6-2,C15orf41,NPTX1,IGSF11,PDYN,GPR173,ANLN,PLP1,MAPK9,RPE,SATB1,SH3BP2,CLUAP1,SPP1,TCF7L2,NSD1,TPM2,FLRT2,TOM1L2,VLDLR,TSPAN11,ZBTB14,MKRN3,TUBA1A,FAM13C,MSRB3" Coexpression M8836 Genes up-regulated in hematopoietic stem cells versus multipotent progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "CACNG1,LRBA,B4GALT6,BTF3L4,MFSD4A,CSF3R,DDX46,POM121,FAM107B,DLG3,DNM1L,E2F5,RASGRP2,PTK2B,FGFR3,AMOTL2,SYT3,DBF4,GPR37,CIT,KCNJ4,MDM4,MEF2C,PAK3,PDE1A,PIK3CD,MTMR10,PTK2,ZIK1,RAB5B,RGS3,MYH14,HES6,SOX6,SH3BGR,FAM102A,SH3GL2,SLC1A2,SLC8A1,TET1,SOX5,SRPK2,VAMP1,DICER1,C9orf85,UCHL1,FXR1" Coexpression M8209 Genes up-regulated in germinal center B lymphocytes over-expressing: PRDM1 [GeneID=639] versus Epstein-Barr virus protein LMP1. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABR,SRPX,PPFIA4,APOC1,APOC2,USP2,SCARB1,CPNE6,LY86,COL11A2,CSF1R,CSF3R,PDE4DIP,CYBB,GPRASP1,SIRPA,TOM1,ABCC5,EDN1,RASA4,SRPK3,PLEKHO1,STX2,TLR7,FCGR1A,ACSS1,STARD3,NCKAP1L,HMGCL,KCNH1,KCNQ2,PIK3CD,PRKCG,CYBC1,RAB3IL1,RXRA,ITSN1,SIRT2,FNBP1,RGL1,ICAM5,BEX4,ELP5,TSC2,TUB,KLC2,PLD4" Coexpression M9542 Genes up-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABCF1,ADAR,AK2,CAPRIN2,STOML1,IPCEF1,GAPVD1,MYEF2,EGR3,EIF1,EMX2,RRAGB,NRN1,KAT8,AMOTL2,FHL1,SESN1,GOLGB1,CROCCP2,KIT,LSS,AFDN,MX1,NBL1,NCAM1,ING3,LRRN3,PIGG,TRIM68,YY1AP1,FBXW7,S100B,SMPD3,KBTBD4,POGZ,TTBK2,KANK1,STXBP1,DICER1,CHST8,ZMAT3,ZMYND8,LAT2,WNK1,EVI5,SNX27,ITM2C" Coexpression M6314 Genes up-regulated in macrophages primed by IFNG [GeneID=3458]: untreated versus stimulated by IFNG [GeneID=3458] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "AXIN2,APC,LGR5,CA8,CAPN3,CDH10,CDO1,RBM39,VCAN,CST3,DBN1,ENO2,EPS8,AGAP3,EVL,ATP2C1,SRCAP,GGT5,TNRC6A,DOCK7,KCND2,MBNL1,COMMD5,NCAM1,OPRL1,CNTN3,FAM216A,RASGRF2,WLS,SCP2,HES6,SCAF8,SH3BP2,ARX,ST8SIA1,SLC1A6,RBM26,SRPK2,KLHL7,BEX4,C9orf85,METTL3,VLDLR,LAT2,REEP1,MAP3K12,RTN4" Coexpression M5586 Genes up-regulated in comparison of central memory CD4 [GeneID=920] T cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "OSBPL8,BIN1,CAPRIN2,CAPN3,DCLK1,ZFYVE9,CLOCK,GPRASP1,ZNF337,DMTF1,SNX29,TENM1,F8,GABRA3,RAPGEF6,TDRKH,DIDO1,NR3C1,BTN2A1,HAS2,BACH2,KCNN3,NACA,DPY19L2P2,PCDH8,PDE3B,PIK3R1,FTO,SMIM7,MTRF1L,ZCWPW1,RADX,CLSTN1,TTC17,SPATA7,ARHGAP26,POGZ,SSTR1,GSE1,VAMP1,TCF7,AHCYL2,EMSY,MVB12B,MARCH8,JMJD1C,SSPN" Coexpression M8983 Genes up-regulated in CD4 [GeneID=920] T ceels over-expressing FOXP3 [GeneID=920] and PPARg1 isoform of PPARG [GeneID=5468]: untreated versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADGRF5,ARRB1,PLA2G4C,ASCL1,PTBP2,KRIT1,KIAA1549L,CNTN1,SLC4A7,CLOCK,PITPNM3,DOCK4,RASSF2,ARNT2,EXOG,HSD17B14,ST3GAL6,SORBS1,SMC2,GRIK2,SPACA9,HTR2A,MN1,FXYD6,NRGN,OLR1,FXYD1,C11orf49,PRPH,ZFHX4,CDK5RAP3,SLC11A1,ATF7IP,INAVA,DOP1A,LHPP,MAPK8IP3,APOM,SYNE2,VPS13A,DOCK9,TGFBR3,CDH22,TRPS1,TTTY15,ZNF74,SPHK2" Coexpression M9859 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NDRG3,AP2A2,SNX32,KCNAB2,DGKZ,PDXK,ARRB2,N4BP2L1,ADAM15,CBR1,AP4M1,CDH8,LRWD1,ARHGEF6,IFFO1,DCAF8,E2F6,AASDH,SLC43A2,RTN3,SIRPB1,UBE2E3,PCYOX1,FLYWCH1,POMT1,FAM49B,SESN1,ADAP1,RNF165,COQ10A,LDLRAD3,EPN1,TATDN3,PTPA,PRKCB,SEC14L1,SGK1,IFT122,FAM168A,TAF6,DNMBP,KIAA0930,SZT2,CRTC1,ATP13A2,ZFP91,ZMYND8" Coexpression M7251 Genes up-regulated in thymus subcapsular cortical region versus the whole cortex. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "TXNDC16,LTBP4,AMPD3,ANK3,APBB2,GPAM,ARRB1,CAPRIN2,ATP1A1,B3GALT2,RGS11,CBR1,AKAP7,PITPNC1,DNM1,GNE,EEF1A2,AASS,LRRC23,F5,RPS6KC1,ST3GAL6,FCGRT,STRADA,FHL1,SYNCRIP,TPK1,SESN1,GP1BB,PRDM5,GSTM5,ZHX1,KITLG,NBL1,SLC11A2,ANLN,CDIP1,RPS6KA2,HES6,RASA3,SCG5,SLC15A2,RGL1,NACC2,BEX4,CADM1,IFT88" Coexpression M3461 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from adult blood. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ATP1B3,ST3GAL5,ARHGEF7,LDLRAD4,SLC25A14,CD38,CLGN,COPB2,MYL6B,MAGED1,FEZ2,ARHGAP32,DBI,JAKMIP2,EXOG,MED12,E2F5,EGR3,ARMCX1,FECH,TMEM164,FOXM1,SMC2,GUCY1B1,ARHGAP19,ACOT7,IDH3A,MKLN1,CD200,C11orf49,PSMA6,PEX5,TMEM231,CEP97,ERI2,RFX5,RIC8B,RMI1,ASRGL1,SLA,CDK19,DNMBP,CBX5,TP53BP1,GORASP1,C12orf4,NUP214" Coexpression M6290 Genes down-regulated in macrophages: untreated versus stimulated by IFNG [GeneID=3458] for 3h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADCY6,SYT13,AQP4,CADPS,EIF4G3,BCHE,CCNT1,LOC730101,CDR1,LHX2,DGKG,DCT,ECM2,RGS17,FCGR1A,ST3GAL6,GABRB1,TRAF3IP2,ARPP21,SPIN1,GPR19,STON1,GRK4,TUBA1C,HPR,KCND2,ADAM11,SERPINE2,NLE1,EPB41L4B,POU3F2,PLPPR1,PEX2,RORB,SYNDIG1,CCDC88A,SLC12A2,SLCO1A2,KIF1B,RALYL,SLC19A3,NACC2,TRH,DNAJC12,KCNK12,ZBTB38,EMSY" Coexpression M5220 Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADD3,ABCD2,AMT,ASGR1,PROM1,CAMK2A,CAMK2B,SLC25A14,CBS,MYOM2,FOXN3,COL4A5,COL9A2,COL9A3,C2CD2,ABCG1,CRYM,CSNK1E,IP6K1,SUGP2,REEP2,SH3YL1,SEMA4D,FOLH1,RAPGEF4,KAT7,GUCY1B1,KTN1,MATN2,ADAM11,CD200,NACA,PKD1,PMP22,PTH1R,RGS10,EXD2,SEC31A,SLC1A2,ZFR2,USP22,TIAM1,TP53BP1,TRIO,AMOT,UPF3A,PCBP4" Coexpression M3418 Genes down-regulated in comparison of regulatory T cell (Treg) versus effector T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "CSMD2,SEMA7A,RNF182,CBLN1,CLTA,MICAL2,TM9SF4,EPHB1,SPEG,FDFT1,GAD1,TUBA8,GNAO1,ATF7,PLCD4,RABL2A,SOX21,CELF3,RBPJ,HES5,MARK1,KITLG,MPP2,NAP1L1,NF1,ALDH1L2,NOVA2,NPTX1,GPR173,MBOAT7,IRX1,CRTAC1,PRIMA1,HOGA1,SCN2B,SH3GL2,BCAN,RPH3A,SLC9A5,SYT1,TMEM121,SLC35A4,UGT8,WNT7A,REEP1,SEMA3B,PDSS2" Coexpression M3771 Genes up-regulated in comparison of control dendritic cells (DC) at 24 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ACTN2,ADD1,KIF1A,BAIAP3,CAMK2G,AP4M1,LETMD1,FEZ2,KIAA0513,DCT,ACOT8,DUSP9,ANKRD46,EPB41,ERBB2,CEND1,F5,FCGR1A,FOXO3,DLL3,GLUL,GPR34,GRIK5,CIT,LINGO1,MAN1B1,HLF,JAK1,L1CAM,ARHGAP12,MBP,LRP1B,SMIM11A,KCNIP3,HES6,IFT122,KIF13A,DBNDD2,ELOVL4,APOM,ACSL6,AHCYL2,ITGB3BP,ERCC6L2,CELF4,EVI5,HRASLS" Coexpression M8504 Genes down-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ACTN1,NDRG3,NDRG2,ADCY6,ADRB2,KCNAB2,SFMBT2,CASK,MAP7,ENTPD6,ABCG2,MAP4K4,CNN3,BTF3L4,CD99L2,ABCC5,RASGRP2,SLC9B2,CINP,NSG2,GART,GGT5,IL6R,IL6ST,SETD4,PDE4B,SERPINI1,PLEC,POLG,RGS7,RGS10,SELL,RASA3,SCAF8,SGK1,SCG5,ST8SIA1,SPTAN1,NACC2,LRRC8A,SSBP2,TUBB2A,EIF4ENIF1,VSNL1,SLC30A4,TUBA1A,NAV2" Coexpression M7366 Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "RALGAPA1,NDRG3,GPAM,CHID1,CAST,CBFA2T2,ENTPD6,C1orf52,CDC25B,TMEM59L,DNAJB5,COL4A5,COL11A2,NCOR1,TENM4,FEZ2,NRSN1,USP6NL,CX3CR1,MYADM,EARS2,YTHDC1,KIAA0753,TMEM130,HS3ST4,TOM1,EZH1,RASL10A,DLL3,GAA,FAM120B,RAB40B,ATOH8,GPR155,NEFH,DDR2,PRTG,GPR173,ST8SIA5,STRN3,RASGEF1B,FAM120C,RFX5,KANSL3,SMOC1,KIAA1107,ST8SIA2" Coexpression M9195 Genes down-regulated in T reg: NRP1+ [GeneID=8829] versus NRP1- [GeneID=8829]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NDRG2,ADCY6,ADD1,ARHGAP20,APBB2,SLC7A14,ATP1A1,ALDH7A1,NRP2,CACNA1A,DDR1,VSTM2A,RCBTB2,MAP4K4,CSNK1E,DLG3,SLC12A6,PLEKHO1,RASGRP2,MRVI1,FDFT1,FOXO3,GALC,KCNMB4,GRIK1,MYLK2,KCNH2,KTN1,STMN1,SYTL4,TM6SF1,PURG,SYTL2,ZSCAN2,RBBP8,RPRD1A,LGI2,FOXRED2,SATB1,ATXN2,RASA3,MCF2L,ICAM5,TTC3,PORCN,STMN4,LMAN2L" Coexpression M7474 Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus TGF beta. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "PLEKHG5,ADCYAP1R1,KIAA1324,CCDC146,ATP1A2,KSR1,DDR1,SYT6,C2CD2,PLCH2,NCAN,DZIP3,BRINP1,SPATA2,ELMSAN1,RUSC2,TRAPPC9,GABRA5,WASF3,RAB30,ZBTB45,HSPA1L,KCND3,NCAM2,NRCAM,PBX1,PCMT1,ST8SIA5,PLXNB3,TNPO2,GON4L,FAM184A,RFX2,RGS12,CARF,YJEFN3,ELMOD1,NLGN1,SMARCD3,TMCC1,TACR1,MLST8,TSC1,RICTOR,WIPF2,FBXO36,DPF3" Coexpression M9439 Genes up-regulated in normal T reg (nTreg): FOXO1 [GeneID=2308] versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SLC12A5,ARHGAP5,FOXK1,MS4A7,KMT2C,SEC24C,CST3,GAPVD1,PITPNC1,ZC3H11A,DDX46,G3BP2,DMTF1,PHF20L1,LPAR6,TNK2,USPL1,OLIG2,ST3GAL6,KIAA1109,COQ5,CELF1,GABBR1,GABRA2,ZMYND11,RAPGEF6,PRRC2B,MAT2A,MBP,MEF2C,NFIA,PIK3CD,PRKACB,TUG1,RPL38,RASA3,SGK1,EMC1,MYCBP2,ALG1,SZT2,ARHGEF12,AP4E1,TK2,HIRA,ZSCAN26,MRPL47" Coexpression M5266 Genes up-regulated in comparison of macrophages exposed to 5 worms/well B. malayi versus macrophages exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SYN3,NDRG2,ADCYAP1R1,ADD1,BCAR3,MRTFA,SEMA7A,CDK10,ATP2B3,LINC00847,BSN,ENTPD6,CDC25B,LY86,FAM149A,MAGED1,CRYBB1,NCOR2,MICAL2,SGSM2,DTNB,EEF1D,SIRPB1,FGR,LILRA2,DIDO1,KLF12,MEF2C,MX1,NBL1,NFYA,MAPK8,ATXN2,NTNG1,CLSTN1,SLC6A8,KDM4B,SOX2,SSTR2,TACC1,CLASP1,TNR,TPM1,UBTF,VAV1,SLC13A3,UPF3A" Coexpression M3523 Genes up-regulated in comparison of naive CD8 T cells versus activated CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "METAP1D,CEP126,CARNS1,MARCH3,ZBTB10,SNAI3-AS1,LDHD,BAIAP3,CFAP410,KMT2C,CLCN4,DAPK3,B3GAT3,RUSC2,DNM2,DTNA,ST8SIA3,KMT5B,LRRC23,TOMM40L,AGAP2,USP21,DLL3,ABLIM2,PHYHIPL,GPR34,COQ10A,LIX1,ITGAM,KCNJ4,KCNJ10,KHK,MN1,ADAM22,MYO7A,NFIA,NTRK3,GLIPR1L2,SYTL2,BSDC1,FAM102A,STAU1,VAMP1,ANKRD12,RFTN2,PLPP4,SHD" Coexpression M7530 Genes up-regulated in stimulated by anti-CD3 double positive thymocytes: ELK1 [GeneID=2002] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "C1QTNF1,ALS2,MTMR3,SIPA1L1,KBTBD11,DLG3,DRD1,C8orf37,VPS13B,RABEPK,DUSP27,NELFCD,FAM49B,ARFGAP2,MUM1,LMO2,FGFBP3,MEIS2,MYO7A,NUMA1,TBC1D25,GPR85,FAM216A,QRICH1,ZYG11B,RFX3,MAPK12,FAM19A1,PUF60,SLC12A2,PBLD,ZC3H4,MLST8,VWA3A,SZT2,PUM2,CYB561A3,TIAM1,CBX5,DDHD1,TP53BP1,METTL3,ZMYND8,TUB,GORASP1,C12orf4,NETO2" Coexpression M6390 Genes up-regulated in plasma cells versus germinal center B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NCKAP5,PLEKHG5,UNC5A,CHID1,B3GALT2,MTMR3,LDLRAD4,LONRF2,ANKRD35,MAML1,SACS,PHF20L1,TMEM132C,EFEMP1,ZMAT1,AHCYL1,TMEM8B,ADAM28,EML4,CECR2,GRIA1,MAEL,ZDHHC15,OPALIN,DHX35,LIX1,MATN2,PDE3A,PLEC,PTPRG,ATG16L1,FBXW7,CPEB3,SLC9A5,ABTB1,SOX1,ERC1,IQSEC2,STOX1,FCHO1,MAPK8IP3,ELOVL4,NEK4,TAF6,PCDH20,ZIC3,ST7" Coexpression M9171 Genes up-regulated in CD4 [GeneID=920] T conv: over-expressing IKZF4 and LEF1 [GeneID=64375;52276] versus control. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADD1,ZNF608,WDR35,ARHGAP20,ARNTL,MTMR3,CFAP410,QKI,ABCG1,USP6NL,GPRASP1,DAPK1,IP6K1,FBXO25,YAF2,EPB41L2,STX2,ARMCX1,BRPF3,KIAA1958,STON1,GRIK5,BACH2,CELF5,ICA1,SCIN,IL6R,LIG4,POC1B,AFF1,CD200,RTL5,NUCB2,C11orf49,PPM1B,RALGDS,GTDC1,KIF7,SPTAN1,SPTB,SULF2,SYT11,TEX15,TIAM1,WBP2,PHTF2,VANGL2" Coexpression M6633 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] and 180 min stimulation of: LPS versus IL10 [GeneID=3486] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABR,C3orf14,ELFN2,NME5,BBOX1,TTC9B,HCN2,NGB,CD38,WHRN,CRHBP,NCOR1,ABCG1,SEC14L5,C8orf34,LYPD1,DYNC1I1,F8,SPECC1,PRELID3A,GALNT15,IP6K3,STARD10,HPGDS,GLUL,CREG2,MITF,CD200,SCG3,PDE1A,CAMKV,GDPD1,PTPRN2,ZFP30,CNKSR2,SLC8A1,MBD5,SP4,UHRF1BP1L,BEX1,CLASP2,PRRC2C,ZFR2,SLC37A2,GPR161,CDH22,DCBLD1" Coexpression M3568 Genes up-regulated in comparison of CD4 [GeneID=920] T cells from bone marrow versus those from spleen. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "BEND6,WDR35,TTLL9,BARD1,PROM1,KALRN,RCBTB2,FAM171B,GDA,CYBB,SRGAP3,TUBD1,MTSS1L,ANKRD13B,F5,F8,SEMA6C,ZNF512,GABRA3,C1QL1,GNG4,GPR12,ADAMTS8,GRM7,SOX21,WIF1,PADI2,HRH3,ARHGAP36,HP,LMO2,PIK3AP1,TM6SF1,COMMD5,ROGDI,FHOD3,SLCO1A2,SSTR2,CD27-AS1,PCDHB7,TF,ANKRD24,ZBTB16,FBXO36,MSRB3,SLC4A10,FAM181A" Coexpression M8547 Genes up-regulated in KLRB1 high [GeneID=3820] T cells: CD8A [GeneID=925] versus CD8A CD8B [GeneID=925;926]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADCYAP1R1,TBC1D14,TXNDC16,BIN1,BCL2L2,BTK,HIP1R,LDB2,CBFA2T2,CD81,CFL2,LY86,CNN3,SLC4A7,RTTN,ZNF385A,MYADM,DYRK1A,EIF4G2,SRPK3,EYA1,ARFGAP2,NEURL4,GAD1,STARD3,GSN,FICD,IRF8,INPP1,KTN1,MEF2C,NCAM1,NCF2,NUCB2,PRKCB,MRPS18A,RYR1,SAFB,MAPK12,SELL,ITSN1,TCF4,TK2,TPD52,C9orf85,WBP2,PHTF2" Coexpression M8001 Genes down-regulated in bone marrow-derived macrophages treated with rosiglitazone [PubChem=77999]: wildtype versus STAT6 [GeneID=6778] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "RALGAPA1,ADORA3,TAOK1,LGR5,PDXK,ATP1B3,CNOT8,NRXN2,STOML1,CYBB,AIF1L,ZEB2,TENM1,EZH1,PRKAG2,C2orf88,SARAF,ABLIM2,GPR37,TPPP,ADAMTS6,SYNPO,LDLRAD3,CDK14,ZFYVE21,PLTP,PURG,PPP3CA,PTK2,PEX2,PLEKHB2,PRR5L,FOXRED2,CHD9,MBD5,RGL1,VAMP1,SYN1,KIAA1107,VAV2,WRN,CLDND1,XRCC4,LMAN2L,SIGLEC10,RNF146,SENP7" Coexpression M9563 Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=10219] knockout versus BCL2L11 [GeneID=10018] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ALCAM,PCDH10,ATP2B2,CANX,CDH8,HECTD1,RBM39,DCAF4,SPOCK3,RABGAP1L,TMCC2,DMD,CDON,PDCD6IP,FEM1B,EIF4G2,SRPK3,CORO2B,FKTN,FAM49B,CAMKK2,GABRA2,ATP8A2,GGT5,ADAMTS8,RASSF8,HNRNPK,NEFH,PC,NKAIN4,LRRC49,OCIAD1,RDX,ARHGEF10L,ATXN2,NTNG1,SLC8A3,SMARCD3,PDZRN3,ASTN2,DNMBP,TPM3,IL34,ZFAND5,WNK1,HNRNPA3,FXR1" Coexpression M9757 Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus Ly6c int CXCR5+ [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "C1QC,CAMK2G,CBS,ZNF385A,ABCG1,CSF1R,MBNL2,PTK2B,EFEMP1,FCGRT,KHDRBS3,ADGRA1,GAB1,GJB1,GPT2,GPR37,RAPGEF4,BACH2,GATD1,CREG2,KLRC2,L1CAM,NODAL,RETREG1,SLC25A23,HMGCLL1,POU3F4,RGS10,LGI2,TMLHE,ARMH4,IL17RB,ZNF365,SLC11A1,ZNF667,SNAP25,TNIK,NMNAT2,SPP1,EPB41L3,TF,NPL,TPM2,LAT2,FSTL5,DNALI1,SENP7" Coexpression M6970 Genes up-regulated in naïve macrophages: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "GALNT16,RNF150,CC2D2A,CEP126,CADPS,CAMK2A,LONRF2,SEC14L5,ZEB2,HEPH,RHOBTB1,DLG3,ARRDC4,MFSD10,BRSK1,DENND2A,CPLX2,ALDH1L1,CYP46A1,GK,ADGRA3,FUT10,PCLO,NCKAP1L,IPO5,AFDN,MN1,MIR4697HG,NEFH,NPR2,SCHIP1,PTPA,VSTM2L,TMEM100,ST6GALNAC6,RTKN,FOXRED2,EFHD1,KIF13A,SEPT8,ATP13A2,TIMP4,TTC3,TTPA,VLDLR,NSD2,ST7" Coexpression M7457 Genes up-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NDRG2,DGKD,ARRB2,C5,RCBTB2,TPP1,NMT2,ANKRD44,CSF1R,CSF3R,CYBB,KLHL3,AK5,DPYSL2,ATL1,ABI2,SORBS3,RASGRP2,RCSD1,FAM198B,HVCN1,FYN,GABBR1,ADAM28,GGTA1P,GSN,NCKAP1L,TTYH2,MITF,NCAM1,NFE2L2,NRCAM,PDE3B,SNRK,MARCH1,RNASE1,PNMA8A,UEVLD,RTN1,YPEL4,SLC8A1,CCDC88A,TBL1X,SLC44A1,SSBP2,PRDM8,NLRP3" Coexpression M6639 Genes down-regulated in bone marrow-derived macrophages at 45 min stimulation by LPS: wildtype versus IL6 [GeneID=3469] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "CPNE2,SLC12A5,OSBPL1A,ADAM15,ST3GAL5,BTRC,CCK,LRBA,SOCS6,RNF14,CSF2RA,MYADM,RUSC2,DOCK2,USPL1,DNAJC27,RPS6KC1,UBE2E3,C2orf88,ZBED3,DOT1L,GHDC,MN1,NFE2L2,NUCB1,PENK,CNNM2,PTPRE,RIPOR1,MARCH1,RTKN,RYR1,FOXRED2,SATB1,SLC1A3,PEX26,SLC12A4,INTS9,NCDN,STXBP1,SYT11,MCF2L,CLDND1,PMEPA1,NT5M,TMEM178A,AMN1" Coexpression M4948 Genes up-regulated in comparison of monocytes versus myeloid dendritic cells (mDC). MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "PDXK,BACH1,RCBTB2,MAP4K4,IFFO1,CSF3R,VCAN,CYBB,KIAA0513,FBXL5,USP3,FRY,EIF1,RTN3,SIRPB1,F5,FAM198B,CHST15,FGR,SEMA4D,FYB1,GLUL,LILRA2,IRAK3,HNMT,ITGAM,MXI1,FXYD6,NCF2,PILRA,ARHGEF10L,WLS,RXRA,ATXN1,ARHGEF40,SLC11A1,SLC22A4,SMARCD3,DMXL2,TCF7L2,TIAM1,NACC2,TLR4,TNFRSF1B,NPL,BEST1,NLRP3" Coexpression M9751 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ALCAM,NRP2,IL33,CACNA1B,SLC5A11,ENTPD6,CREB5,OSBPL3,ELMSAN1,SACS,RAB39B,CDON,EGR3,CERCAM,FGF12,SEMA4D,GAA,MALT1,HPGDS,GNG4,ATOH8,TOX2,NXPH3,RBPJ,IL6ST,ITGAV,NRGN,PFKP,RETREG1,HMGCLL1,PMP22,RASGEF1B,PTPRN,RGS3,RPS6KA2,SARS,PREX2,SPP1,BEX1,ITPRID2,FLRT2,LAT2,AMZ1,FSTL5,PRDM8,SCG2,ADAMTS10" Coexpression M8087 Genes up-regulated in myeloid-derived suppressor cells: bone marrow versus colon tumor. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ACTN1,SORCS2,GAS7,ALS2,TMEFF1,ASPH,RAB29,CD86,B4GALT6,PPP1R16B,MYADM,SIRPA,ZEB2,HS3ST2,CPEB2,HIPK3,PLEKHA1,EIF1,EPS8,CLVS1,TPPP3,GLS,PARD3B,MAP4K5,IL6ST,KCNC1,LIFR,VWA5A,MAN2A2,AFDN,PFKFB3,DIRAS2,PTK2,PRR5L,LARP4,SYPL1,TCF4,DMXL2,NACC2,TNFRSF1B,PRRT1,TPD52,TRIO,TUB,ANKS1B,PMEPA1,SEMA3B" Coexpression M5280 Genes up-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NDRG2,CACHD1,SLC7A14,CACNA1E,CALB2,IPCEF1,LONRF1,KCTD8,SPOCK2,CNIH3,AK5,ARRDC4,HSD17B14,CACNG2,KIAA1109,PNMA2,WASF3,CSDC2,FERMT2,FAM19A2,IGSF21,MIER3,ZDHHC15,SMAD9,TM6SF1,NEXMIF,PBX1,PDE3A,SEMA5B,PLP1,POU3F4,RASGEF1B,LAMA1,ATG16L1,RGS4,FBXO11,CCDC92,SLC1A6,UNC80,NPAS3,NKAIN2,ADHFE1,TBX15,CLHC1,PLEKHH2,CADM2,NAV3" Coexpression M6552 Genes down-regulated in CD8 T cells: early passage clone over-expressing TERT [GeneID=7015] versus late passage control. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ARID1A,KIDINS220,DGKD,ARRB1,NUMB,BACH1,CHM,CRY2,CSNK1E,GALNT9,PDE4DIP,RASSF2,DAPK1,DNAJC6,PDCD6IP,ABCC5,TENM1,CELF1,ABLIM2,ZNF274,NR3C1,MAP4K5,RASSF8,IL6R,ITPKB,TTYH2,MYO9A,CDIP1,POLG,PRKCZ,WBP1L,PEX5,RFX3,CCDC82,RPS6KA2,CASC3,KIAA0930,TCF7,VWCE,THRA,SMUG1,TRIO,TUBB2A,RICTOR,WIPF2,FRMD6,RNF146" Coexpression M7086 Genes up-regulated in CD4 [GeneID=920] T cells from non-atopic donors: resting versus stimulated with allergen (house dust mite). MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ACTN2,BRAP,APBB2,EIF4G3,CBFA2T2,MYL6B,HECTD1,HINFP,TRIM69,TOX,FBXO25,SEC16A,HIPK3,WAC,SUCO,SEMA4D,HVCN1,STAG2,GABRG2,HBS1L,FAM120B,ERAP1,RUNDC3A,ZNF276,SPIN1,FERMT2,LNX1,MAP4K5,HAS2,KCNMA1,SESN3,MYO6,NFE2L2,NTRK3,PBX1,QRICH1,RPS6KA2,IL17RB,PEAR1,SEC31A,SLC4A3,DBNDD2,MMS19,WIPF1,RICTOR,CSDE1,DOCK8" Coexpression M8146 Genes up-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABR,KLRC4,SRPX,OGT,ATP2B2,ATP2B3,AZGP1,CD86,DLGAP1,ARHGEF10,APPL1,CTIF,AK5,DMPK,MED12,DNM2,ATN1,EPHB1,FYB1,GABRA5,GAD2,STARD3,HTATSF1,GPM6B,MCHR1,GRIK2,ADAMTS13,GSN,ATXN2L,MBNL1,MDM4,PROX1,PTPRN,C1orf54,FEZF2,TMEM206,AMBRA1,BCAN,CDK5RAP3,SHANK2,ATF7IP,PALLD,ARHGAP26,ST5,STXBP1,ZNF177,NETO2" Coexpression M8099 Genes up-regulated in spleen B lymphocytes with IRF8 [GeneID=3394] knockout: marginal zone versus follicular. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "PTCHD1,APP,CACNA1D,PRC1,USP2,CDH2,CCPG1,FAM19A5,COL4A5,SUMF2,FAM171B,UBXN2A,SPOCK2,ASB3,PAN3,AMOTL2,FOLR2,ST6GALNAC3,TCERG1,KCNMB4,FRMD5,HNMT,C5orf24,NAT8L,LDLRAD3,PPM1L,NEXMIF,IDNK,ANLN,DEF8,PTPRG,RIPOR1,RXRA,SEC14L1,FHOD3,DZIP1,MAPK8IP3,SYNE2,TF,DDHD1,CSMD1,PRMT8,ZMYND8,TSC2,PROCA1,NLRP3,SPATA13" Coexpression M9124 Genes down-regulated in T reg: XBP1 [GeneID=7494] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ASIC1,NDRG2,SEMA7A,BID,KSR1,FMNL3,CD86,CD81,TJP2,OSBPL3,TBC1D5,PITPNC1,RABGAP1L,CHRDL1,SLC29A4,CDON,PLXNC1,STAU2,NEK6,SEPT9,KCNMB4,LOXL3,GPR34,KLF12,IL6R,LYPLAL1,MBD1,THYN1,P2RY13,PLEC,PACSIN1,DRAM2,REV3L,ATXN1,SLC12A2,MYCBP2,RAP1GAP2,SYT11,VPS13A,SYNE1,ARHGEF12,AHCYL2,ZMAT3,ITM2C,JMJD1C,SSPN,GAN" Coexpression M4012 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABCD2,APOC1,N4BP2L1,HCN2,CBR1,ABCG2,RTTN,NECTIN3,NCAN,INTS1,FIS1,SNX29,EGFR,ELAVL3,DCTN4,EN2,IGSF6,RACK1,TOMM40L,BAIAP2,SUCO,NBEA,GABRA3,GGT5,C1QL1,RUNDC3A,LINGO1,SCRG1,MITF,NRCAM,DDR2,GPR88,POU3F2,MAPK10,PRODH,SLC22A23,PTH1R,ELP2,EMID1,ATXN1,ZKSCAN3,CLASP2,SYN2,AKNA,PRRT1,FBXO36,GJC2" Coexpression M5534 Genes up-regulated in comparison of neutrophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SERPINA3,ACTN1,APAF1,ARSF,SYNJ1,RHBDL1,SPAG9,LRRFIP1,FOXN3,MAML1,GIT2,DYNC1I1,SLC12A6,ABCC5,EGFR,ELN,GMPR2,SEC24B,GAD2,GOLGB1,BTN2A1,PACSIN2,HRH3,HTR2A,L1CAM,MARK3,NCAM1,NFYA,NOVA2,NTRK3,PAH,PFKFB3,PKN2,RIPOR1,RASGRF1,R3HDM2,SLC11A1,SLC22A4,CDK19,MAPK8IP3,SYNE2,TBL1X,HEY1,NTSR2,SLC30A3,MPPE1,JMJD1C" Coexpression M5450 Genes up-regulated in comparison of mast cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABHD6,NDRG2,NR0B1,AMPD3,PKP4,MARCH3,CLTC,AKAP12,SOCS5,USP6NL,ZNF804A,GSDME,FRY,KCTD3,EPB41L2,RTN3,TAOK3,FER,SORBS1,CPLX2,GLUL,GRB10,GSTT2,MAOB,MEIS2,MITF,MRPL42,N6AMT1,NPR2,ENPP2,ZFYVE21,LRP12,PTK2,ERI2,RGS10,SHMT2,IDI2-AS1,ITPRID2,STXBP1,CAMTA1,CAMSAP2,DNAJC12,PMEPA1,EVI5,ITM2C,CERS6,TIGD6" Coexpression M9535 Genes down-regulated in skin: uninfected versus S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "NDRG3,AP2A2,GAS7,APOC1,NRP2,AIFM1,SCARB1,CD81,UBE2L6,NSL1,OSBPL3,CST3,SDC3,TBC1D5,RHOBTB1,ABCC5,ANKRD46,EPB41L2,COQ7,IGSF6,CDKL3,TBC1D16,ZNF589,FECH,IQCG,FOLR2,GATM,IGF1,IL11RA,ARHGAP12,MAT2A,P2RY13,PCSK5,PIK3R1,PILRA,CYBC1,QDPR,AP1AR,DGLUCY,FOXRED2,ITSN1,ST6GAL1,SLA,SPP1,WDR7,UBE3B,SMIM8" Coexpression M5007 Genes up-regulated in comparison of myeloid dendritic cells (mDC) from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ABAT,KIAA1324,EP400,PLA2G4C,MARCH3,WASF1,MAP7,RUNX1T1,TPP1,TCEAL2,KIAA0040,SNAP91,DTNA,TENM1,DCTN4,AMZ2,FCGR1B,TESK2,SCARA3,TBR1,GHR,GPD1,GRIN1,PRDM5,HPSE2,MT1M,NCAM2,NFYA,SNTG1,PAX6,PDCD2,ENPP2,PFKFB2,PKIA,C1orf109,ERI2,RLBP1,ZNF821,CCDC92,SYBU,SSTR2,KANK1,CDH22,RUNDC3B,LAMP5,ZNF37BP,CAMK1G" Coexpression M5074 Genes up-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus naive CD8 T cells treated with IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ADCY2,HHATL,BEND6,PCDH19,KIAA1324,C1QTNF4,GAS7,RGS20,CACNA1A,CAMK2A,CAMK2B,STOML1,IFFO1,CNRIP1,IPCEF1,FGF1,JKAMP,SPECC1,MEGF11,HBS1L,CNDP1,RNFT2,FRMD5,HMGB1,KCNN3,SESN3,PTPN13,CASTOR1,SUSD4,RGR,TMEM100,FBXW7,ATP8B4,ST8SIA1,FAM214B,KDM4D,SRPK2,APOM,TTBK2,DIP2A,KLHL7,TMEM150C,ATP11A,ARHGEF12,UBC,MICAL1,MPPE1" Coexpression M3459 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus naive CD4 [GeneID=920] T cells from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "C1QTNF3,DYNLL1,BARD1,ST3GAL5,SLC25A14,CD38,CLGN,MAGED1,SOCS5,EDRF1,C2CD2L,DDX46,PDCD6IP,UBE2E3,FOXM1,SMC2,ARFGAP2,HBS1L,TXNL4A,ZNF638,HTATSF1,GPR19,PSIP1,GUCY1B1,PAXBP1,SMAD1,MBD1,MDM4,SLC11A2,NRDC,HERC2P3,GPSM2,PSMA6,SPDL1,RFX5,UBR7,SEC61A2,CHD9,SMARCA4,TACC1,ZEB1,ITGB3BP,CBX5,METTL3,TRO,NSD2,ZNF177" Coexpression M5005 Genes down-regulated in comparison of plasmacytoid dendritic cells (pDC) from TIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "FAM135A,APAF1,SGCE,CALM1,CCNH,AKAP6,SLC4A7,HDAC4,SMG7,FEM1B,KMT5B,EIF4G1,EN2,GPHN,TAOK3,HBS1L,SPIN1,ATXN2L,KLF12,KIF2A,NACA,OGDH,TNPO2,PPP2R5E,GON4L,PSMD13,C1orf54,TMEM206,ASRGL1,SHMT2,ST6GAL1,FNBP1,CLUAP1,MYCBP2,ARHGAP26,GSE1,TAF9,WASHC4,CLASP1,HIF3A,ZMAT3,R3HDM1,TRPS1,ZMYND8,UBE3A,OSBP2,NSD2" Coexpression M5229 Genes up-regulated in comparison of dendritic cells (DC) exposed to 5 worms/well B. malayi versus DC exposed to M. tuberculosis MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ASIC1,ADD1,ADD3,ADORA3,GAS7,FAM131A,APOC1,ASTN1,ADAM15,CCNH,CHN2,RAB33A,CLTB,LY86,COX4I1,NCOR2,ST18,SGSM2,ABCC5,SUGP2,FCGRT,FOXO3,FOLH1,SRCAP,GFRA2,IDH3A,INPP1,ITGAM,LMO2,MAN2A2,PTOV1,NACA,PCSK5,PLCB2,RGS10,RNASE1,RNH1,SGK1,SH3BGR,SEC31A,SLA,SMARCE1,SPTAN1,CAMTA2,TBL1X,TPM1,CLIP2" Coexpression M5276 Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "RALGAPA1,ACTN1,CARNS1,AMPD3,OGT,SEMA7A,DGKZ,ASPA,CA4,LDB2,ARHGEF2,CDO1,LRWD1,CLU,IPCEF1,TMEM170A,GIT2,ARMCX4,ABCC5,EBI3,TNK2,CALCRL,DENND4A,HSPA12B,CHST15,FGFR1,GPR153,RAPGEF6,NCKAP1,BRD8,PCDH11X,KIT,PAXBP1,MTTP,SH3KBP1,BSDC1,CLSTN1,SLC11A1,TMCC1,TNIK,RAP1GAP2,SRPK2,FGD4,ROBO3,DMXL2,ZEB1,SIGLEC10" Coexpression M6563 Genes down-regulated in monocyte-derived dendritic cells: rosiglitazone [PubChem=77999] versus AM580 [PubChem=2126]. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "ARID1A,NDRG3,ARHGEF1,SLC4A7,PITPNC1,KBTBD11,SLC12A6,RASGRP1,TNK2,CALCRL,MEX3B,HVCN1,SDCBP2,ACSS1,GRK4,RAPGEF4,SPACA9,IRAK3,INPP5B,ITGA7,PDCD2,ABCB1,PIK3CD,PIK3R1,SLC25A23,PLTP,SEPT4,PRKACB,PTPRE,TTLL7,RNASEL,RYR1,SATB1,SUPT20H,RASA3,SGK1,FAM102A,DOCK10,MAST1,CABCOCO1,SULF2,MGRN1,PIK3R5,ZSCAN26,SHD,SNX14,KLHDC1" Coexpression M7839 Genes up-regulated in resting T reg versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 1.91E-03 1.00E+00 1.57E-02 1.56E-01 47 200 "SYS1,BIN1,FGD2,TNRC6C,MADD,ARRB1,MAP7,CCPG1,KIAA0040,MYADM,RIPOR2,FBXO25,SLC12A6,ARRDC4,RASGRP1,FRY,PHF20L1,MRVI1,TRAF3IP2,SESN1,DCLK2,RAPGEF4,RAPGEF1,PADI2,JAK1,NUCB2,PXK,OXR1,BSDC1,CCDC82,EMID1,FAM102A,SLA,WDR47,MTERF2,CPEB4,ARHGAP26,SYNE2,VPS13A,DNMBP,ZEB1,PSD3,FRYL,CYB561A3,MTMR14,ZMYND8,JMJD1C" Coexpression M8896 Genes up-regulated in multipotent progenitors versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.92E-03 1.00E+00 1.58E-02 1.57E-01 41 169 "ACTN1,DGKZ,CHN1,IPCEF1,RIPOR2,RASSF2,ARMCX2,KLHL3,PHF20L1,PLEKHA1,LRRC17,REEP2,CHST15,PDLIM5,AP4B1,AGFG1,IGF1,MBP,CD200,HS6ST3,SLC11A2,PDCD2,PDE3B,PIK3CD,SH3KBP1,SLC26A11,STK32A,PEX5,ZSCAN2,TTC13,EMID1,SATB1,SCG5,ST6GAL1,ST8SIA1,DZIP1,PJA1,CAMSAP2,GPRIN3,LRRC8A,SSBP2" Coexpression M5957 Genes specifically up-regulated in pancreatic beta cells. MSigDB H: Hallmark Gene Sets (v6.0) 1.92E-03 1.00E+00 1.58E-02 1.57E-01 14 40 "SYT13,CHGA,GCK,INSM1,LMO2,NEUROD1,NKX2-2,PAK3,PAX6,PCSK1,PCSK2,SST,STXBP1,ABCC8" Coexpression M1610 All significantly up-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.95E-03 1.00E+00 1.61E-02 1.60E-01 89 428 "DGCR6,ADCY2,ADD3,KIAA1324,SRPX,APBB1,CPNE5,IGDCC4,ATP1A2,BCL7A,NRP2,BLM,IL33,CA4,MTMR7,NEURL1,DCLK1,SLIT2,CLU,FAM189A2,NSL1,SIPA1L1,VCAN,GREB1,ECE2,BOC,SNAP91,EDNRA,RGS17,EFS,EYA1,RACK1,FCGRT,SPSB4,FLNC,FLYWCH1,MPP6,STARD10,IGSF5,FAXC,C1QL1,GLRB,GSTT2,IGF1,NKD1,KCND3,LAMA2,STMN1,MATN2,MEIS1,MMP16,CCDC80,MSI1,MYCN,NCAM1,NFIA,NFIX,PALM,PCDH8,PCDH9,PENK,PLTP,PSAT1,FAT3,PRKAR1B,RELN,PTN,TMEM231,LGI2,EMID1,MEG3,HUNK,SLC4A3,TET1,CXXC4,SOX11,CLSTN2,SYNE2,DNAJC9,TMEM151B,ZFPM2,CBX5,HSPBP1,CADM1,RBFOX3,KCNT2,CELF4,SLC38A1,PCBP4" Coexpression M18685 Genes up-regulated in macrophage by live P.gingivalis. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.96E-03 1.00E+00 1.61E-02 1.60E-01 99 484 "SEMA6A,LTBP4,MIER1,CADPS,ATP2B1,ATP2B2,SLC2A11,CFLAR,CA8,EVI5L,DLGAP3,DNAJB5,AKAP12,HAPLN1,NCOR2,NCAN,CALY,FGFR1OP2,DCAF8,HDAC4,IST1,BRINP1,ZEB2,KLHL3,DYNC1I1,CDON,SHANK1,RCAN1,EDN1,EDNRA,FRY,EPB41,TLR7,F3,ACSL4,FCGR1A,IQCG,SEMA6C,DOT1L,GABRA1,GFER,TTBK1,GNAS,FERMT2,GPM6A,ATP2B1-AS1,MFSD2A,SLC2A6,FAAP20,IRF8,ST7-AS1,LIFR,HECTD2,LSS,MBNL1,SYT9,MN1,ADAM22,NDP,DNHD1,DDR2,P2RX7,SNTG1,PDE2A,PPP3CC,RASGEF1B,SLC22A23,ANKHD1,PTX3,IQSEC3,ZCWPW1,SLC6A15,ARMC5,ATXN1,SEC14L1,SFPQ,SLC1A2,SMTN,CPEB4,PALLD,KIF1B,ZBTB43,LMO3,SRPK2,KANK1,COBL,ADGRL3,WWC1,KLHL4,DMXL2,TCF7L2,PSD3,HEY1,BHLHB9,TNS1,TPD52,SHD,HPS4,KCNAB1" Coexpression M1723 Top 100 ranked genes most specific to the cerebellum region of adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.97E-03 1.00E+00 1.62E-02 1.61E-01 24 85 "KCNT1,ARHGAP5,RNF182,CALB2,TJP2,ZNF521,FEZ2,DMD,SLC25A18,EN2,FAM107A,GAREM2,KIT,NHLH1,NKAIN4,PAQR6,PREX2,ERC1,SYNE2,TST,HEPACAM,AMOT,ZIC1,ZIC2" Coexpression 18667080-TableS4 Human StemCell_Kocer08_185genes GeneSigDB 1.97E-03 1.00E+00 1.62E-02 1.61E-01 39 159 "ACTN1,ALCAM,APP,LGR5,ALDH7A1,PRC1,DCLK1,LHX2,CLU,CNR1,CRYM,SNCAIP,VCAN,MATR3,DCT,DPYSL2,EDNRB,RASGRP1,FGFR1,FYN,DKK3,GFRA1,GPM6B,PRDM5,GSTM5,GUCY1B1,WIF1,BACH2,IL6ST,L1CAM,MITF,CD200,NASP,PAK3,PCSK2,PIK3R1,TCF7,TRPS1,VSNL1" Coexpression M2372 Genes up-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-1 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.97E-03 1.00E+00 1.62E-02 1.61E-01 17 53 "CLTC,CNN3,CREM,E2F5,EDN1,SYNCRIP,ARFIP1,HNRNPK,SMAP1,IGF1,PMP22,PRKACB,FNDC3A,KAT6B,TPM3,UBE2H,TBC1D15" Coexpression M2098 "Genes up-regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip-seq data." MSigDB C2: CGP Curated Gene Sets (v6.0) 1.99E-03 1.00E+00 1.64E-02 1.62E-01 164 857 "EMILIN3,ELFN2,SLITRK1,ADCYAP1R1,AXIN2,HHATL,FZD9,UNC5A,AGT,DISP3,KCNT1,APLP1,APOC1,AMER3,AQP6,ATP1A3,KIF1A,FGF17,CACNA1I,CDK5R2,CA4,CACNG1,CABP7,NGB,CAMK2A,BRSK2,CBLN1,CBARP,CHI3L2,CHRNA4,TMEM59L,TMEM184B,TMEM155,IGLON5,GAL3ST1,TOGARAM2,SLC32A1,CSF1,PLCH2,SLITRK5,PHYHIP,TMEM130,PARD6A,EEF1A2,EFNA2,EGR3,C3orf18,EMX2,EN2,ENO2,EFS,TMEM74,REEP2,ZIC4,PRAM1,CHST15,OLFM1,FGR,AGAP2,ZMYND15,SEMA6C,DPYSL4,TMEM151A,SIGLEC8,C1QL1,RND1,AIFM3,PCSK1N,LILRB4,GPR12,B4GALNT4,PLPP7,GRIN1,ADAMTS8,GRM2,GSTM5,SOX21,TMEM179,IGSF21,HRH3,IGFBPL1,TLX1,CFAP126,KNDC1,SLC6A17,C2CD4C,KCNA6,KCNC1,KCNJ4,KIF5A,LMO1,LSS,MAG,MN1,MSI1,NRBP2,MT3,MYL3,MYO7A,NEFM,NKX2-2,NPTX1,ZDHHC22,TREM2,PCDH8,CDK18,TMIE,PLCB2,SMOX,SEPT4,FSD1,IRX1,SLC26A11,KLK6,NDUFS7,WDR25,PTH1R,FEZF2,PRIMA1,KCTD17,ARHGEF10L,KLHDC8A,SOX8,SCN2B,LRRTM4,ASIC4,TRIM46,BCAN,SLC4A3,SLC2A5,SLC6A7,SHANK2,SNCB,SST,SSTR1,AJAP1,CNTN2,SMG6,WSCD1,PCDHA7,PCDHA1,CHST8,ZNF34,TIMP4,TNFRSF1B,PRRT1,TNNT1,PIK3R5,CDK20,TRH,KCNE5,TUB,HEPACAM,MGAT5B,VAV2,LGI4,ATP6V0E2,SLC26A10,CELF4,WNK2,TMEM63C,CAMK1G,VANGL2,FAM181A" Coexpression M2686 Genes up-regulated in myometrial cells over-expressing ATF2 [Gene ID=1386] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.99E-03 1.00E+00 1.64E-02 1.62E-01 45 190 "BRAP,APAF1,DGKZ,BAIAP3,KCNAB3,ARHGAP22,NRXN2,SMARCAL1,DCAF4,C2CD2L,LYPD1,REEP2,CORO2B,FGR,FOXG1,FOXM1,DENND2A,ADAM28,PCSK1N,PTPRT,GSTT2,HMX1,KCNA2,KCNK3,MAP2,NEFM,NNAT,PLXNB3,FSD1,CEP41,BAALC,SH3BGR,FAM102A,ABLIM3,EFHD1,DIP2A,ZFR2,ATP13A2,CBX5,PRMT8,TRPM2,CA14,VIPR2,TRIM9,LAS1L" Coexpression M7733 Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 0h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 2.01E-03 1.00E+00 1.64E-02 1.63E-01 37 149 "SYN3,FMNL2,OGT,SEMA7A,CDK13,INSYN2B,B3GALT2,SYNJ1,IGFN1,COG1,LRIG1,DNAJC6,DDX46,TRAPPC9,DOCK2,MBNL2,IP6K2,ATP2C1,TNRC6A,AFF1,CLEC9A,PDPK1,SH3KBP1,R3HDM2,SLC6A11,BTBD7,SMARCA4,BDP1,KLHL7,VAMP1,SYNE1,DICER1,R3HDM1,KAT6B,CHST5,VAV2,MICU3" Coexpression M11837 "Genes whose expression decreases with age in normal kidney, excluding those with higher expression in blood." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.01E-03 1.00E+00 1.64E-02 1.63E-01 37 149 "C3orf14,AK2,AMT,PPFIA1,BMP7,THSD7A,CTH,GPRASP1,DBT,KLHL3,AASS,GAD1,AHCYL1,GHR,TOX3,GNAS,PCLO,FRMD3,LINC00667,MTR,PALM,FA2H,SLC22A23,PLPPR1,PTPRO,SLC25A36,CPEB3,BCAN,SHANK2,SP2,ZBTB43,CLASP2,TPD52,ZNF711,ZFAND5,WNK1,RTN4" Coexpression 20013794-Table3 Human CardiacCells_Haag09_64genes GeneSigDB 2.01E-03 1.00E+00 1.64E-02 1.63E-01 19 62 "SGCE,CAPN3,ECE2,DMD,EGR3,ERBB2,SPEG,FHL1,PDLIM5,BVES,ITGA7,LAMA2,MBNL1,MEF2C,TAGLN3,MAPK12,MRAS,SMTN,TCF12" Coexpression M3274 Top up-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.01E-03 1.00E+00 1.64E-02 1.63E-01 19 62 "ACLY,KDM5D,APLP1,CHRM4,LHX2,OLFM1,GABRB3,GABRG2,HSP90AA1,NUCB1,PLEC,POLR2F,SLC1A2,SEPT8,KANK1,THBS4,CBX5,TP53BP2,LRP8" Coexpression M2855 Genes up-regulated in NOMO-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 2.01E-03 1.00E+00 1.64E-02 1.63E-01 64 291 "HECW2,MAP4K3,CAPRIN2,ASPH,MTMR9,SYNJ1,C1QC,PTBP2,CAMK2D,CFL2,DOCK4,DAPK1,JAKMIP2,ZEB2,CNIH3,WDR20,ARNT2,NR1D2,SLC12A6,FAM13A,EGR3,KCTD3,CLVS1,FAM198B,SEMA4D,ZMYND11,MYOZ2,GCNT2,ADAM28,HNMT,IFI16,LRRC25,IL6ST,KIFC3,DPP10-AS1,VWA5A,HECTD2,TM6SF1,KITLG,SLC11A2,OLR1,RETREG2,PTPRO,PTX3,PID1,TMEM255A,RNASEL,UEVLD,SGK1,FNDC3A,BTBD7,CPEB4,ANKRD12,TBCEL,PSD3,GPRIN3,AKTIP,WBP2,TUBB2A,CADM1,ZIC2,SCG2,CAB39L,GAN" Coexpression M1828 "Genes important for Sertoli, peritubular, Leydig and interstitial cells, based on mouse models with male reproductive defects." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.01E-03 1.00E+00 1.64E-02 1.63E-01 11 28 "NR0B1,BCL2L2,MAP7,B4GALNT1,MAN2A2,KITLG,CLDN11,SOX8,SBF1,SLC12A2,SF1" Coexpression 15532095-Table3 Human Prostate_Kristiansen05_188genes GeneSigDB 2.02E-03 1.00E+00 1.65E-02 1.63E-01 31 119 "KIAA1324,SHTN1,MTMR3,CCK,ENTPD6,COPB2,CHN1,CLU,AKAP12,DAPK1,EFEMP1,FGF1,FLNC,FOLH1,CAMKK2,GJB1,WIF1,JAK1,KIT,VWA5A,ENPP2,PENK,PIK3R1,PTN,RTN1,SLC12A4,SLC14A1,TACC1,TGFBR3,TJP1,VSNL1" Coexpression M405 Genes up-regulated in of bone marrow progenitors with MIR223 [GeneID=407008] knockout: 4- versus 8-day cultures. MSigDB C7: Immunologic Signatures (v6.0) 2.02E-03 1.00E+00 1.65E-02 1.64E-01 36 144 "DGCR6,RTL9,APOC1,MPDZ,BSN,CNTN1,ARHGEF10,CNIH3,SACS,ERBB4,APC2,CORO2B,DPYSL4,GCNT2,GHR,GRIN2C,PTPRT,SLC2A6,NEGR1,IGFBP1,BRINP3,KCNA1,KCND2,NEUROD2,PALM,TMOD2,PRIMA1,KCTD17,SLC4A3,SNAP25,NFASC,CLSTN2,CADM1,CLEC2L,NAV3,DPF3" Coexpression M6590 The 'NPM1-mutated signature 2': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to the AML cases with the intact gene and without recurring cytogenetic anomalities or M7 phenotype. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.03E-03 1.00E+00 1.66E-02 1.65E-01 35 139 "ALK,CAPRIN2,CDK5R1,DST,CACNA1I,CACNA2D1,NIPBL,COL4A5,AKAP12,DZIP3,CTH,MBNL2,STAG2,PPARGC1A,GK,MCHR1,HSP90AA1,LIMS1,MAN2A2,MEIS1,NCAM2,NFE2L2,DPY19L2P2,PDE3A,PDPK1,PKN2,SPDL1,MAP6D1,LGR4,PLPPR3,ASRGL1,SRPK2,ZFR2,IQCE,TST" Coexpression 19101988-Table2a Human Breast_Habermann09_38genes GeneSigDB 2.04E-03 1.00E+00 1.66E-02 1.65E-01 12 32 "KIAA1324,ALCAM,GREB1,ARMCX2,DMTF1,ARRDC4,EVL,CSPG5,SYT17,IPO5,PKD1,DNALI1" Coexpression M1939 Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.04E-03 1.00E+00 1.66E-02 1.65E-01 12 32 "NCKAP5,ATP6V1G2,ZNF599,STOML1,RTTN,GGT7,GDAP1L1,ZIK1,PPP2R3C,KCNIP2,SHANK2,PAK5" Coexpression M7720 Genes down-regulated in bone marrow-derived dendritic cellstreated by poly(IC): 1h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 2.04E-03 1.00E+00 1.66E-02 1.65E-01 34 134 "ADD3,TAOK1,MAP4K4,AKAP7,CSNK1G3,MTX3,IRAK4,ZBED3,TNRC6A,GPR22,JAK1,VWA5A,MATN2,NFE2L2,PDPK1,PNMA3,MED1,PPP3CB,PTK2,CEP97,BEND5,RBBP6,FAM161B,R3HDM2,BTBD7,ATF7IP,MAPKBP1,SP4,KDM4C,ARHGAP26,KLHL7,TCEA1,WNK1,NT5M" Coexpression M2185 "Genes up-regulated in ovarian tumors from mouse models for the BMP SMAD signaling (gonad specific double knockout of SMAD1 and SMAD5 [GeneID=4086, 4090])." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.04E-03 1.00E+00 1.66E-02 1.65E-01 34 134 "TMCC3,PNMA8B,SORCS2,APBB2,BMP7,ARHGEF25,KMT2C,LRIG1,SIPA1L1,EFS,MRVI1,TAOK3,CSDC2,SPIN1,PRUNE2,NR3C1,GSN,CAMK2N2,MATN2,MEIS2,NFIX,CDK14,PLTP,SEPT4,PKIA,ENOX1,ZHX3,ZNF423,LRRC4,MCF2L,TCF4,WIPF1,RGMA,STOX2" Coexpression M19170 The 'NPM1-mutated signature 1': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to all AML cases with the intact gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.04E-03 1.00E+00 1.66E-02 1.65E-01 61 275 "AK2,ALK,FAM131A,CAPRIN2,ATM,CFLAR,CDK5R1,DST,CACNA1I,CA12,CACNA2D1,CHGB,TJP2,NIPBL,CNR1,COL4A5,DZIP3,CTH,IP6K1,FEM1B,FRY,MBNL2,DLC1,ARFIP1,PPARGC1A,GK,MCHR1,KIF3A,HMGB1,AGBL5,HSP90AA1,LIMS1,MAN2A2,MEIS1,NCAM2,NFE2L2,CNOT4,DPY19L2P2,PCDHGC3,PDE3A,PDPK1,SNX10,SCHIP1,PPP3CC,PKN2,APTX,PTCH1,SPDL1,LGR4,PLPPR3,ASRGL1,SH3BP2,ATF7IP,SRPK2,ZFR2,MTCL1,IQCE,DOCK9,CHST5,TST,WNK1" Coexpression M2255 "Genes commonly up-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.06E-03 1.00E+00 1.68E-02 1.67E-01 58 259 "ABHD6,ADRA1D,DGKD,ATP1A1,KSR1,ST3GAL5,KALRN,HIP1R,UBE2L6,ARHGEF6,AKAP7,HAPLN1,TRIM69,USP6NL,DAPK1,SIRPA,ZEB2,SLC12A6,DPYSL2,ELN,EPB41,FGFR1,TMEM164,CSPG5,AP4B1,FYN,SDCBP2,C1QL1,GPD2,TOX2,PADI2,ITGAM,JAK1,KCNN1,KIT,MDFI,IL17D,TAGLN3,NKX2-2,CDK14,FAT3,SH3KBP1,PPARA,PTPN13,RGS10,SH3GL3,NTNG1,FNBP1,SYNE2,TCF12,HHIP,TNNT1,TMEFF2,DNAJC12,SLC17A7,SSPN,DPF3,SPATA13" Coexpression M2690 Genes up-regulated in C57MG cells (mammary epithelium) by over-expression of WNT1 [Gene ID=7471] gene. MSigDB C6: Oncogenic Signatures (v6.0) 2.08E-03 1.00E+00 1.68E-02 1.67E-01 43 180 "SERPINA3,AP1B1,PLA2G6,MYOM1,ADGRB1,MYRF,FOXK1,ENTPD2,CHRNB2,VAX2,CPS1,CRMP1,DCC,DTNB,ST8SIA3,RASGRP2,SYT3,DPYSL4,TPK1,ADAM28,GRIN2D,FICD,HES5,INSM1,KCND3,KCNJ9,KCNN1,SYT9,MKLN1,THYN1,NBL1,NEUROD2,NF1,OLR1,PDYN,SEMA5B,PTPRO,SLN,MAPKBP1,VAMP1,TCF7L2,UGT8,HPS4" Coexpression M8043 Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype t(8;21) ; has AML1 ETO fusion [GeneID=861;862]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.11E-03 1.00E+00 1.71E-02 1.70E-01 22 76 "AP1B1,MYRF,BAIAP3,RUNX1T1,CACNA2D2,ARHGEF6,RASA4,NCALD,SCML2,TRAF3IP2,HPGDS,PALM,RGS10,ROBO1,BAALC,STK32B,IL17RB,KDM4B,BEX1,PSD3,TRH,LAT2" Coexpression M13251 "Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point, 12 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.12E-03 1.00E+00 1.71E-02 1.70E-01 65 297 "RBM10,ADD1,ADD3,AQP4,CDC14B,RGS20,ATP2A2,DST,SYNJ2,CACNA1E,SPAG9,AP4M1,CDC25B,NIPBL,MICAL2,PDE4DIP,SLITRK5,RIPOR2,TOX,SIRPA,NR1D2,DTNA,EGFR,ERBB2,ERCC2,ETV1,FGF13,CAP2,FOXF2,STAMBP,TRAF3IP2,STON1,CIT,HAS2,AGFG1,ITPKA,MMP16,NEK1,NEUROD1,NPTX1,NUMA1,PDE1C,PDGFRA,PIK3CD,GPSM2,PLCD1,PLEC,PRRX1,PRKAB2,SLC6A15,REV3L,NLGN4Y,SMARCE1,ZCCHC24,CLUAP1,GLT8D1,CAND2,SPTB,ST5,TCF7L2,SYNE1,TJP1,TPM2,TRIO,AMOT" Coexpression M383 Genes up-regulated in dendritic cell NIK NFkB2-KO versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated. MSigDB C7: Immunologic Signatures (v6.0) 2.12E-03 1.00E+00 1.71E-02 1.70E-01 42 175 "AS3MT,ACTN1,ADD3,USP28,GAS7,PHYHD1,CDC14B,ARHGAP5,ATP2B1,GPR146,EPS15L1,SLC25A27,CX3CR1,RIPOR2,ELMO1,KBTBD11,DOCK2,FRY,PLXNC1,RASGRP2,RCSD1,FGF13,IQGAP2,RAPGEF4,BACH2,ITGAM,GPR155,SLC11A2,PDE2A,PIK3R1,PRKCB,RFX3,FBXW7,RXRA,SELL,RASA3,ARHGAP26,RAP1GAP2,TCF7,FRYL,PIK3R5,TPM4" Coexpression M6703 Genes down-regulated in endothelial cells: interferon beta versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 2.12E-03 1.00E+00 1.71E-02 1.70E-01 42 175 "ACLY,ADD1,TXNDC16,GAS7,CHID1,MTMR9,BARD1,BCS1L,PRC1,AIFM1,CD38,CDC25B,PCYT1B,NCOR2,HP1BP3,E2F6,EIF4G1,ECSIT,TAOK3,PRKAG2,PCYOX1,MSL1,INPP5B,JAK1,NCOA7,POC1B,DBNL,NUMA1,OPA1,GLIPR1L2,XRN1,SH3KBP1,PTCH1,QDPR,CHD9,SEPHS1,FAM168A,SYT11,TAF6,HIRA,UBTF,CERS6" Coexpression 17597811-SuppTable3 Human Leukemia_Mullighan07_237genes GeneSigDB 2.12E-03 1.00E+00 1.71E-02 1.70E-01 47 201 "ACLY,ADAR,LTBP4,ALK,DGKD,CAPRIN2,CDK5R1,DST,SYNJ2,CACNA1I,CACNA2D1,NIPBL,COL4A5,AKAP12,ABCG1,DZIP3,PPP1R16B,CTH,EEF1D,MBNL2,LPAR6,SORBS3,FHL1,STAG2,PPARGC1A,GK,MCHR1,GUCY1B1,HSP90AA1,LIMS1,MAN2A2,MEIS1,NBL1,NCAM2,NFE2L2,PDE3A,RETREG1,PKN2,SPDL1,MAP6D1,LGR4,ASRGL1,SRPK2,ZFR2,IQCE,TCF7,TST" Coexpression M12027 Genes up-regulated in HCT8/S11 cells (colon cancer) engineered to stably express NTN1 [GeneID=1630] off a plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.15E-03 1.00E+00 1.73E-02 1.72E-01 8 17 "NRXN3,PLXNC1,TOX3,KITLG,RDX,FBXO11,FHOD3,SATB2" Coexpression M1725 Transcripts showing subcellular localization to both distal and proximal dendrites in the adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.15E-03 1.00E+00 1.73E-02 1.72E-01 8 17 "CAMK2A,DLG4,EPB41L1,HPCAL4,SOWAHA,KIF5A,PSD,BTBD3" Coexpression 16109776-Table3 Human Leukemia_Verhaak05_50genes GeneSigDB 2.15E-03 1.00E+00 1.73E-02 1.72E-01 16 49 "APP,ARHGAP22,COL4A5,LPAR6,FGFR1,HPGDS,MEIS1,MEST,MN1,CD200,PDE3B,GPSM2,BAALC,DMXL2,TRH,ITM2C" Coexpression 15161681-Table1 Human Stomach_Antonescu04_51genes GeneSigDB 2.15E-03 1.00E+00 1.73E-02 1.72E-01 16 49 "LTBP4,SGCE,CCKBR,NRG2,CSF1,CALY,WASF3,LAMA2,NOS1,PDGFRA,SCHIP1,SMTN,SOX11,TGFBR3,TP53BP1,TPM1" Coexpression 20035825-TableS5a Human Lung_Mikkonen10_62genes GeneSigDB 2.15E-03 1.00E+00 1.73E-02 1.72E-01 16 49 "SEMA6A,CEP126,CABP7,TMEM35A,FOLH1,FOLR2,ZDHHC15,PIK3AP1,SYT9,PDGFRA,EPB41L4B,SEC61A2,DMRTC1,SYT5,HIF3A,ZFP41" Coexpression M18742 "Genes whose reduced expression in nasopharyngeal carinoma (NPC) correlated most with the increased expression of EBNA1 [GeneID=3783774], a latent gene of Epstein-Barr virus (EBV)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.15E-03 1.00E+00 1.73E-02 1.72E-01 41 170 "ACTN2,USP35,PITPNM2,FGD2,KCNAB2,PRX,ZFYVE28,CACNA1I,ARHGEF1,RUBCN,KIAA0513,PLEKHM1,SIDT2,FGF11,NEU3,STARD3,RAPGEF1,FAM107A,HSD17B1,SYT9,MSRA,NHLH1,DNHD1,PACSIN1,POU6F1,WBP1L,PTPRE,ZDHHC14,KCTD17,SMPD3,RASA3,EPN2,LIMS2,SLC6A11,WDTC1,CAMTA2,SYT11,MCF2L,ARL10,VAV2,GDPD5" Coexpression M3247 Genes up-regulated in comparison of IgM-memory B cells versus Ig isotype switched memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.17E-03 1.00E+00 1.75E-02 1.73E-01 46 196 "ADORA1,NLGN4X,MYH7B,EPB41L5,APOC2,LGR5,ARNTL,RGS11,MTMR7,SULT4A1,ERC2,DPP6,EYA1,CACNG2,HPCAL4,FOXO3,FOLH1,GABRB1,ADGRA3,SCRG1,IL6R,KCNJ5,KLHL23,KCNK2,MYL3,OPCML,OLA1,PLXNB3,LRRN3,SIDT1,ZMAT4,TTLL7,SEMA6D,SLC9A5,SLC22A4,CLSTN2,KANK1,SYP,PCDHGA9,SLC35G2,GPR161,CDH22,RPRM,UCHL1,XRCC4,HRASLS" Coexpression M6522 Genes up-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 2.17E-03 1.00E+00 1.75E-02 1.73E-01 46 196 "ABR,ALCAM,PDXK,MPDZ,KSR1,NIPA1,CACNB2,RCBTB2,CHN1,LRIG1,TOX,GIT2,ZEB2,SV2A,DLG3,TOM1,OPTN,KATNAL1,FYN,RAPGEF1,TTYH2,SESN3,MIR4697HG,RTL5,ODF2,OGDH,GPR137C,PDE1B,PPP2R5C,CEP97,GTDC1,RXRA,ATXN1,SEC14L1,KIF21A,ST8SIA1,SEPT8,SYT11,CAMTA1,SYNE1,ARHGEF12,TGFBR3,TNFRSF1B,CLDND1,LRP8,NLRP3" Coexpression 18285497-tableS1 Mouse Liver_Garcia08_454genes GeneSigDB 2.18E-03 1.00E+00 1.76E-02 1.74E-01 75 352 "ADAR,ALCAM,MAP4K3,APP,ARRB2,EIF4G3,STX16,C1QC,MMD2,SRSF11,TMEM184B,LY86,ARMC8,CTNND1,PUM1,DCT,ALKBH8,CALN1,DOCK2,CACNG7,SH3GLB1,RCSD1,FGF1,FAM49B,INPP5K,GATM,TNRC6A,RAPGEF4,MAPT,MBNL1,MIA2,NAP1L1,PDE4B,PDYN,STRN3,MASP1,PTPRE,RAB3IL1,RASGRF1,ZDHHC14,SLC25A36,AP1AR,TNFRSF19,SUPT20H,KIF21A,ITSN1,MAGI3,DHX30,ZKSCAN3,SLN,CXXC4,SNCA,LMBRD1,FNBP1,MYCBP2,TEX2,MPRIP,ZC3H4,DDHD2,DNMBP,TBCEL,FBXW11,CLASP1,PCDHGA11,AKNA,ARHGEF12,ZMAT3,ENHO,TNFRSF1B,TPM2,TPM4,TRIO,WNK1,SLC38A1,AAAS" Coexpression M8120 Genes up-regulated in IL10 and NFKB1 [GeneID=4790;3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 2.19E-03 1.00E+00 1.76E-02 1.75E-01 40 165 "ACTN1,ACTN2,DPP10,AMER3,NCOA1,HAP1,ADGRG1,STOML1,DNAJB5,TOX,TOMM20,SHANK1,DTNB,PRAM1,CORO2B,FGF11,SDCBP2,RUNDC3A,AIFM3,KCNMB4,MAP4K5,ITGA7,HECTD2,PTOV1,NPTX2,PLCB2,PACSIN1,PRKCB,EML5,NTNG1,SSTR1,OBSL1,GPRIN3,ACTR6,SEZ6L,MGAT5B,LGI4,PROCA1,PMEPA1,FAM181A" Coexpression M4594 Selected genes down-regulated in WS1 (fibroblast) in response to irradiation with low dose UV-C. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.20E-03 1.00E+00 1.77E-02 1.76E-01 20 67 "EIF4G3,CDH2,CDH18,SLIT2,C2CD2,MICAL2,SIPA1L1,ZNF804A,MEIS2,NAP1L1,CDK14,FTO,SLC20A2,FNBP1,ERC1,EHBP1,SATB2,USP32P2,NAV3,LAS1L" Coexpression M11763 Genes commonly up-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [GeneID=595;1019]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.20E-03 1.00E+00 1.77E-02 1.76E-01 20 67 "LCORL,LINC00847,CBFA2T2,ZFP28,NRSN1,MAGI2,ARMCX1,SLC9B2,LINC00667,MYT1,PAH,ENPP2,SATB1,SCG5,ZNF423,PBLD,C12orf76,ZNF610,RNF170,KLHDC1" Coexpression M5659 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 2.22E-03 1.00E+00 1.78E-02 1.77E-01 39 160 "ADD3,APOC1,MARCH3,ATP6V1G2,ADAM23,SYNJ2,LDB2,SEPT7,CHI3L2,NMT2,STOML1,MAGED1,PUM1,KLHL3,SNX29,TENM1,EXTL2,SEPT9,IL6ST,DIPK1A,PCDH9,ENPP2,RETREG1,LRRN3,PKIA,APTX,SUSD4,GAL3ST4,ROBO1,SCN3A,ITSN1,FAM102A,LIMS2,MAPKBP1,TNIK,VPS13A,MTCL1,CAMSAP2,SMIM8" Coexpression M2402 Genes down-regulated in E14 ES (embryonic stem) cells upon knockdown of CYCT2 [GeneID=905] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.23E-03 1.00E+00 1.79E-02 1.78E-01 18 58 "SNX30,CRLF1,SLC4A7,CERCAM,ST3GAL6,SMC2,SALL3,GSTT2,HAS2,NEXMIF,NODAL,EPDR1,CEP97,TRIM67,TET1,ZC3H13,LEFTY2,TRH" Coexpression M18517 Genes changed between developmental stages of Valpha14i natural killer T lymphocyte cells (NKT). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.27E-03 1.00E+00 1.82E-02 1.81E-01 97 475 "ACLY,ALS2,DDX3Y,DST,CA8,CACNB4,SYT6,CD38,LGI1,MAGI1,RCBTB2,LY86,UBXN2A,MYADM,RIPOR2,ARHGAP24,SV2A,NR1D2,EBF1,EDIL3,EPS8,SPEG,EFEMP1,ST3GAL6,FHL1,SYNCRIP,TACC2,MPP6,GABRA1,B4GALNT1,SESN1,GGT5,PPARGC1A,DHRS4,GPR34,MAP4K5,HSP90AA1,ICA1,IGF1,DOCK7,TUBB2B,STMN1,MATK,TM6SF1,MEF2C,MYCN,MYO5A,NRGN,NTRK3,NUCB2,ENPP2,ABCB1,PKM,EXOSC10,PRRX1,TNPO2,POLG,PPP2R5C,PPP3CC,MAPK10,SYTL2,PSMD13,PTPRD,RAB3IL1,SLC6A15,SEC61A2,RPS6KA2,SARS,SOX6,SGK1,ITSN1,SHMT2,MAST1,SP4,KIF1B,EPB41L3,ELOVL4,ATMIN,TCF4,TCF7,ATP13A2,TF,HEY1,TJP1,TNNT1,STXBP4,CADM1,UBE3A,MTCH1,WIPF1,SLC13A3,ZNF23,FMN2,ZBTB16,ZNF189,PMEPA1,EVI5" Coexpression M2885 Genes down-regulated in epithelial lung and breast cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 2.27E-03 1.00E+00 1.82E-02 1.81E-01 63 287 "ASIC1,ADD2,ADORA3,BBOX1,TRMT9B,PPFIA2,PPFIA3,MYOM1,HCN2,PROM1,CACNA1I,MYOM2,FAM189A2,VAX2,AKAP6,WHRN,HEPH,ELMO1,DTNB,KCNMB2,ZNF391,APC2,FGF1,FGFR3,IQCG,FLT1,TBR1,GABRA4,TMEM8B,GP1BB,GRIA1,IL12A,KCNB1,MYH7,NEUROD1,NOS1,PBX1,PCSK2,PDE3A,SLC25A23,SIDT1,CNTLN,ZSCAN2,CCDC102B,EMID1,SYNDIG1,PAQR6,KCNIP2,RYR1,SCN7A,NLGN4Y,SH3GL3,SLC6A9,RIMS1,SOX11,COBL,TEX15,DAAM2,RUNDC3B,TRPM2,TRIM9,SLC30A3,AAAS" Coexpression M8944 Genes down-regulated in T reg of aged mice: visceral adipose tissue versus lymph node. MSigDB C7: Immunologic Signatures (v6.0) 2.28E-03 1.00E+00 1.82E-02 1.81E-01 37 150 "AMER3,TTLL9,CDH2,EVI5L,GAL3ST1,SH2B1,CSF3R,RASSF2,TMEM170A,DLG4,EPHB1,TLR7,NSRP1,ZMYND10,USP21,GHDC,NEU3,CECR2,HRH3,POC1B,AFF1,OLR1,PTPN13,FAM120C,SCMH1,TET1,SP2,CAMTA2,ITPRID2,CEP68,SYT11,TAF6,TOM1L2,PCDH20,PRDM10,WIPF2,MVB12B" Coexpression 15831697-TableS3 Human Leukemia_Alcalay05_160genes GeneSigDB 2.33E-03 1.00E+00 1.86E-02 1.85E-01 33 130 "ANK1,APP,PROM1,CD38,B4GALT6,ARHGAP22,COL4A5,TMCC2,FECH,EVL,GALC,GATM,HPGDS,GRM3,MEIS1,MEST,MN1,CD200,CYTL1,ABCB1,SNX10,RETREG1,SIDT1,BAALC,RPS6KA2,STK32B,S100B,URGCP,SLC6A8,NAXD,SNCA,TRH,ITM2C" Coexpression M2214 Genes down-regulated in CD4+ [GeneID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.33E-03 1.00E+00 1.86E-02 1.85E-01 81 386 "AXIN2,EPB41L5,PHYHD1,BBS2,ZNF599,PROM1,CASTOR3,CACNB2,MAP7,SLIT2,NRXN3,TJP2,SUMF2,AKAP5,AKAP12,SIPA1L1,ST18,TBC1D5,AIF1L,DBT,POM121,SRGAP3,DMTF1,SLC12A6,PDCD6IP,EDIL3,EDNRB,FHL1,IP6K2,VTI1B,TPK1,CHL1,GATM,ADGRA3,PCLO,INSYN1,VWA5A,LYPLAL1,MIA2,KITLG,MITF,CD200,MYL3,NBL1,NFIA,ZNF655,RETREG1,SCHIP1,MINDY2,PRPSAP2,RELN,SYTL2,PTPRD,REV3L,RGS12,CARF,RPS6KA2,LRRK2,IL17RB,ASRGL1,SUPT20H,FNDC3A,CLSTN1,EPN2,SCMH1,KIF1B,COBL,ASTN2,KAZN,CAMTA1,WSCD1,SATB2,TGFBR3,FBXL16,RUNDC3B,GORASP1,TMEM161B-AS1,LMF1,KCNT2,LOC100506497,PDSS2" Coexpression M17621 Genes up-regulated 9 h after induction of HoxA5 [GeneID=3205] expression in a breast cancer cell line. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.33E-03 1.00E+00 1.86E-02 1.85E-01 51 223 "CLK4,TMEFF1,ARNTL,BACH1,PTBP2,CARS,RCHY1,CREM,RBM39,CREB5,CTH,EDRF1,DMTF1,RCAN1,KMT5B,EIF5,F3,WAC,IP6K2,FOXO3,ZNF44,CAB39,GAD1,ZNF274,CROCCP2,BTN2A1,IFI16,LIG4,MARK3,NEK1,CNOT4,ZNF426,STRN3,ING3,PTN,RBBP6,RIC8B,YY1AP1,ZNF331,SFPQ,SUPT20H,SCG5,CHD9,KDM3A,AGTPBP1,TRPC1,ZNF23,ZNF45,ZNF184,ZNF195,JMJD1C" Coexpression M97 Genes up-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.34E-03 1.00E+00 1.86E-02 1.85E-01 24 86 "ADGRF5,SEMA6A,BBOX1,ALDH4A1,CAPN3,ADGRG1,SLC22A6,CLU,CRHBP,EML1,INPP5K,MAP4,MIA2,MT3,PDE2A,PPP3CC,PTPRB,SLC6A7,ZCCHC24,UNC5B,ATP10B,TEK,TIE1,GDPD5" Coexpression M9945 Genes down-regulated in HeLa cells after knockdown of MED1 [GeneID=5469] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.35E-03 1.00E+00 1.87E-02 1.86E-01 54 239 "FUBP1,DDR1,PTBP2,SPAG9,REPS2,CDH10,ADGRG1,RCBTB2,CREM,CTH,RHOBTB1,NR1D2,RCAN1,DNAJB6,DYRK1A,AMOTL2,CAMSAP1,FHL1,OGA,ERAP1,GNAS,PRRC2B,CROCCP2,GSN,LIFR,MBD1,MEIS1,MN1,PDE2A,RETREG2,EPB41L4B,POLG,PPP3CA,TUG1,SEC61A2,SH3GL2,ST6GAL1,SMTN,RAB3GAP1,TTC17,SNAP25,PALLD,KDM3A,SPTAN1,MTCL1,DNMBP,HEY1,TPM1,TRIO,TST,HIRA,GDPD5,ST7,HNRNPA3" Coexpression 11823860-SuppTable3 Human Breast_van'tVeer02_2460genes_Ergenes GeneSigDB 2.35E-03 1.00E+00 1.87E-02 1.86E-01 340 1910 "CPNE2,TTYH1,SERPINA3,ABAT,NDRG2,FMNL2,FZD9,RNF150,PTCHD1,MTA3,TBC1D14,KIAA1324,TXNDC16,SPARCL1,SPOP,USP35,ALCAM,BBOX1,SYT13,BIN1,EPB41L5,PHYHD1,BCAS1,PDXK,PDE8B,CHRD,ATP1B3,RNF182,AZGP1,ADGRB2,MPDZ,BLM,PROM1,BMPR1B,MTMR2,RAB29,BAIAP3,BTRC,CA12,CACNA1D,DDR1,CACNG1,CALB2,PTBP2,PRC1,CBR1,CLDN10,CD86,LRBA,REPS2,CDC25B,LONRF2,MAGI1,CLGN,CRLF1,NUMBL,CHI3L2,PLEKHB1,CLCN3,CLCN4,COG1,NMT2,NGEF,FADS2,CNN3,COL4A5,LETMD1,COL9A3,SLC4A7,TBPL1,COX4I1,MYRIP,IGDCC3,CP,PREPL,SH2B1,ABCG1,LRIG1,CSNK1G3,IPCEF1,FAM169A,KIAA0040,GREB1,SLC45A1,CYBB,ARHGAP32,PHF19,RASSF2,RIMS3,DAPK1,SPOCK2,AIF1L,GIT2,DBN1,ARMCX2,MYEF2,CEP170,SACS,SGSM2,TMCC2,ARNT2,SEC16A,DLG3,DMD,CPEB2,DOCK2,RCAN1,DUSP9,ABCC5,DNM1L,GOLT1B,EDN1,EEF1A2,OPTN,KMT5B,KCTD3,PCOLCE2,PAN3,VPS13B,COQ7,LRRC17,RASGRP2,GPHN,ERBB4,IGSF6,EFS,SPEG,MRPL37,RCSD1,FABP7,ACSL4,TUBB3,TUBB4A,FCGR1A,CHST15,TMEM164,SCARA3,UBE2E3,FOXG1,CAP2,IP6K2,AGAP2,SYNCRIP,FOXM1,EVL,SEMA4D,COQ5,JKAMP,NBEA,FAM49B,TRIM16,ATP2C1,KHDRBS3,SARAF,FYB1,MTHFD2,STARD10,GPR162,GFRA1,PPARGC1A,DHRS4,BRD8,GLRB,GLS,TOX3,GLUL,KDM2B,GNG4,GPT2,PRRC2B,LILRB4,GPM6B,NUDT21,EML4,SERP2,PTPRT,KIF3A,TMEM25,FAM107A,SLC2A6,PADI2,FRMD3,NCKAP1L,BACH2,VSIG4,ELOVL5,ACOT7,SCRG1,HMGCL,AGFG1,TCEAL6,ICA1,IFI16,DOCK7,IL6ST,ZNF385B,KCNJ3,KCNK1,KIF5C,LAMP2,STMN1,SFXN5,SYTL4,NCOA7,PIK3AP1,AQP11,MATN3,KCTD6,MID1,AFF1,MYO6,NASP,NCF2,NELL2,NOVA1,PALM,PBX1,PCDH8,PDE4B,PFKP,ANLN,RETREG1,XRN1,GPSM2,PLTP,MTRF1L,LRP12,PSAT1,SH3KBP1,POLR2F,MAPK9,SLC26A11,KLK6,LRRC49,DEF8,PIGG,ELOVL2,PTPN13,FAM120C,PTX3,TTC13,QDPR,ROGDI,RDX,FIGN,RGS10,RNASE1,CCDC82,ZNF532,ELP2,PCMTD2,ZNF671,SOX8,RTN1,AP1AR,FNIP1,SELL,MRAS,FAM102A,KIF16B,SHC4,SYBU,ST8SIA1,ABLIM3,SLA,SLC1A3,SLC2A5,SLC9A5,SLC11A1,CPEB4,CXXC4,KDM4B,ZCCHC24,KIF21B,BDP1,SOX10,FNBP1,SOX11,ZHX3,UNC5B,DBNDD2,KIF1B,CDK19,SAMSN1,SMOC1,ERBIN,FCHO1,NCDN,NEK4,RGL1,SULF2,SEPT3,STXBP1,ABCC8,ASTN2,DDHD2,AGTPBP1,EHBP1,TCF7,TRIM2,USP22,PCDHB10,TNS2,GPR161,THBS4,SLC44A1,TMPO,TNFRSF1B,TNNT1,TP53BP2,PDSS1,STXBP4,TRPS1,ZMYND8,SSBP2,SGK3,RPRM,UBE3A,UCHL1,UGT8,DNAJC12,USP1,NPDC1,ZIC1,ZNF711,LYPD6,ZBTB16,MEIS3,PRTFDC1,DNALI1,LRP8,RGMA,RNF103,ITM2C,HRASLS,TMEM63C,ACTR3B,TTC7A,NHSL1,FRMD6" Coexpression 14993899-TableS1 Human Futreal04_427genes_ConsensusCancerGenes GeneSigDB 2.36E-03 1.00E+00 1.87E-02 1.86E-01 77 364 "SPARCL1,MRTFA,APC,GAS7,API5,NCOA1,ATM,BCL7A,BLM,CARS,USP6,CHN1,CLTC,ZNF521,PDE4DIP,DNAJC6,SRGAP3,SLC25A18,EGFR,ELN,OLIG2,GPHN,ERBB2,ERCC2,ETV1,FGFR1,FGFR3,MALT1,GNAS,HLF,TLX1,HSPA1L,IL6ST,JAK1,JAK2,KIT,KTN1,LIFR,LMO1,LMO2,MDM4,MITF,AFDN,MN1,MYCN,NACA,NF1,NTRK3,NUMA1,PBX1,PDGFRA,PIK3R1,PMS2,IQSEC3,RAP1GDS1,RET,FBXW7,ZNF331,SFPQ,SMARCA4,SS18,TAL1,TCEA1,TCF12,NSD1,ARHGEF12,DICER1,TPM3,TPM4,ZNF384,TSC1,TSC2,NSD2,WRN,FIP1L1,GOPC,NUP214" Coexpression M5658 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. pneumoniae infection. MSigDB C7: Immunologic Signatures (v6.0) 2.37E-03 1.00E+00 1.88E-02 1.87E-01 42 176 "ASPHD1,ACHE,GAS7,REPS2,CHRNA4,CPNE6,DNAJB5,CRYBB1,MICAL2,PHYHIP,DUSP9,ST8SIA3,HEYL,PCOLCE2,LRRC23,EPHB1,RTN3,FHL1,TACC2,FERMT2,GRIN1,GSN,ICA1,MAPT,AFDN,NAP1L1,PC,BCAS3,PLPPR3,MEG3,BCAN,SLC14A1,SNCA,WDTC1,ACSBG1,THBS4,TPM1,TRO,OSBP2,VIPR2,GJC2,FXR1" Coexpression 18849563-SuppTable5c Human Lung_not_cancer_Bhattacharya09_84genes_ FEV1PercentPredictedinCOPDAllSubjects GeneSigDB 2.38E-03 1.00E+00 1.88E-02 1.87E-01 21 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,ARHGEF12,UBTF,ZNF23,ZNF177,ZNF248" Coexpression 18849563-SuppTable4 Human Lung_not_cancer_Bhattacharya09_84genes GeneSigDB 2.38E-03 1.00E+00 1.88E-02 1.87E-01 21 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,ARHGEF12,UBTF,ZNF23,ZNF177,ZNF248" Coexpression 18849563-SuppTable5b Human Lung_not_cancer_Bhattacharya09_84genes_FEV1PercentPredictedorFEV1/FVC GeneSigDB 2.38E-03 1.00E+00 1.88E-02 1.87E-01 21 72 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,ARHGEF12,UBTF,ZNF23,ZNF177,ZNF248" Coexpression M11616 Genes whose promoters display higher levels of histone H3 trimethylation mark at K27 (H3K27me3) in hepatocellular carcinoma (HCC) compared to normal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.39E-03 1.00E+00 1.89E-02 1.88E-01 64 293 "KLRC4,HECW2,RTL9,ADGRF5,CEP126,LRCH2,BMPR1B,CACNB2,FAM189A2,MAGED1,CREB5,IPCEF1,ST18,TOX,YTHDC1,GSDME,PLPPR4,MTX3,SLC12A6,ENPP6,NCALD,ADGRV1,DLC1,GLRB,GRM8,GUCY1A1,GABARAPL2,USP51,IGSF1,SCIN,KCNK2,KIF5C,LMO2,SMAD9,MARK1,CTNNA3,RTL5,OPHN1,ZNF827,PBX1,PRTG,PDE1A,TMOD2,RNASE1,FAM192A,SEMA6D,SATB1,CSRNP3,ELMOD1,SLC1A3,KDM4D,LIMCH1,PALLD,PDZD2,TNIK,GPRIN3,CRB1,SSBP2,FMN2,SPIRE1,LINC02210,NAV3,DOCK8,MSRB3" Coexpression M6524 Genes up-regulated in epithelial cells (24h): untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 2.42E-03 1.00E+00 1.91E-02 1.90E-01 46 197 "ABR,ALCAM,PHF12,ARHGDIA,CFLAR,KSR1,VXN,CBFA2T2,LRIG1,MICAL2,TOX,GIT2,MRPL10,KATNAL1,F8,FYN,NCKAP1,GNAO1,GPR19,NR3C1,NCOA7,RTL5,NF1,OGDH,PAH,PDE4B,PPP2R5C,PPP3CA,RDX,GTDC1,ZNF532,UEVLD,RXRA,ATXN1,ZNF821,SH3BP2,CCDC92,ST8SIA1,CLSTN1,FAM214B,FNBP1,SEMA4A,ARHGEF12,SIK3,SPIRE1,LRP8" Coexpression M4658 Genes up-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.42E-03 1.00E+00 1.91E-02 1.90E-01 46 197 "ATP6V0E2-AS1,ACTN1,KLHL32,MTA3,GPRASP2,APBB1,SLC2A11,CARS,SCARB1,NOG,ARHGEF4,ARHGAP32,SLC12A6,ARMCX1,KIAA1958,ADGRA3,ZNF496,USP51,IL6ST,ZNF667-AS1,MEST,THYN1,LAYN,NRCAM,PIK3CD,RETREG1,LRRN3,ZIK1,ZNF844,FAM184A,ZCWPW1,BEND5,GAL3ST4,RFX2,RGS10,EXD2,SOX8,FAM102A,CNKSR2,EFHD1,ROBO3,RNF175,DICER1-AS1,PRRT1,CDK20,MICU3" Coexpression M3472 Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 2.42E-03 1.00E+00 1.91E-02 1.90E-01 46 197 "NDRG3,APBA2,DNAH17,RUNX1T1,INA,NEURL1,LRIG1,COPS7A,LYPD1,SIDT2,LINC00599,PLEKHA1,RASGRP2,EPHB1,RACK1,PACSIN2,HLF,HPSE2,IL11RA,INPP5B,MARK1,MID1,PLEC,SDK2,POLR2F,RBBP6,DPF2,CCDC25,ATAT1,PEX26,SMTN,SLC8A2,ELMO2,SOX2,CLUAP1,SPTB,NSFL1C,PHF24,PSD3,NR2E1,RIMBP2,LILRA4,PDIA2,LAMP5,SLC17A7,FAM182B" Coexpression M10001 Genes up-regulated in dendritic cells with IFNAR1 [GeneID=3454] knockout: CD8A [GeneID=925] versus ITGAM+ [GeneID=3684]. MSigDB C7: Immunologic Signatures (v6.0) 2.42E-03 1.00E+00 1.91E-02 1.90E-01 46 197 "SDE2,C3orf14,PCDH19,ALCAM,LGR5,METTL6,SRSF11,SLC4A7,CPS1,DZIP3,RAB39B,OLIG1,DTNA,RBM12,EIF1,OLIG2,EPHB1,GPM6A,GPR37,PLCD4,GRID1,WIF1,LINC00667,KCNC1,KCNK1,ZNF667-AS1,PCDH8,GPR85,HERC2P3,NALCN,PRRX1,CEP41,ZNF844,ZNF334,SMARCE1,SNAP25,PALLD,GLT8D1,ERC1,BEX1,SOX9-AS1,CLDND1,ZNF711,TCEAL7,PRTFDC1,EVI5" Coexpression M8790 Genes down-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP. MSigDB C7: Immunologic Signatures (v6.0) 2.42E-03 1.00E+00 1.91E-02 1.90E-01 41 171 "ACTN1,SLC25A25,CSMD3,SRPX,MAP4K3,CASK,RASL11B,B3GALT2,CACNA2D1,KALRN,CBFA2T2,CDH8,AKAP12,FEZ2,ARHGEF10,MAGI2,RCAN1,ECM2,EIF1,PRAM1,ATP8A1,FHL1,USP21,GGT5,CECR2,KLRC2,LIFR,CCDC80,MYO9A,OCRL,PDE1A,PURG,PRKACB,RAVER2,RMI1,SGK1,MPRIP,ADGRL3,EHBP1,TNS1,ADAMTS9" Coexpression 16397233-Table2 Mouse Liver_Ryschich06_100genes_DownRegulated GeneSigDB 2.42E-03 1.00E+00 1.91E-02 1.90E-01 25 91 "ADD1,AP1B1,LTBP4,ARRB1,PTCH2,NUMB,LDB2,ADGRG1,CTNND1,MTSS1L,STX2,ATP2C1,ITPKB,KLC1,MEIS1,MYO6,SEPT4,RPS6KA2,EPN2,STXBP1,PCDHGA11,TNS2,TEK,THRA,TIAM1" Coexpression M2504 Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were not affected by p38 inhibitor LY479754. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.45E-03 1.00E+00 1.94E-02 1.92E-01 72 337 "ABR,CLK4,MTUS1,C1QTNF1,AMPD3,KCNAB2,ARRB1,ZBTB10,NRP2,BID,CFLAR,CA12,CARS,C2CD2,CSF1,LRIG1,VCAN,DOCK4,TOX,RCAN1,OPTN,EGFR,TUBD1,ETV1,AMOTL2,PDLIM5,TRIM16,SRCAP,HTATSF1,ADGRA3,SLC2A6,IL6ST,JAK1,SMAD1,MDFI,MEF2C,MEIS2,MID1,OXTR,PDE4A,PIK3CD,SMOX,ING3,PROX1,LRRC49,RIPOR1,BSDC1,RFX5,RGS3,ZFHX4,ROBO1,TMEM156,SGK1,ABLIM3,ARHGEF40,SLC22A4,INAVA,TNIK,FNBP1,PEG10,SSTR2,DNMBP,TCF7L2,HEY1,TNFRSF1B,TRIO,SSBP2,CADM1,CLIP2,ADAMTS9,NAV2,NETO2" Coexpression M8248 Genes up-regulated in T reg: HDAC6 [GeneID=10013] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 2.46E-03 1.00E+00 1.94E-02 1.93E-01 40 166 "ESYT2,HECW2,CNTNAP1,ARRB1,ZBTB10,NCOA1,ATP2B1,RHBDL1,ARHGEF2,LRRFIP1,COG1,PUM1,TOX,GIT2,CD99L2,NR1D2,ABI1,TAOK3,BAIAP2,TUBGCP4,KDM2B,MIER3,AGFG1,ITPKB,KCNA2,MYO9A,PFKP,PLEC,POLG,SNRK,SAFB,ATXN7,HSPA4L,SCAF8,TTC17,TCF7,NR2C2,VAV1,CAMK1G,SPATA13" Coexpression M2452 Genes up-regulated after 10 h of TGFB1 [GeneID=7040] stimulation in MEF cells (embryonic fibroblast) with NFIC [GeneID=4782] knockout vs wild type MEFs. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.47E-03 1.00E+00 1.94E-02 1.93E-01 17 54 "SPARCL1,CD38,CSF1,AIF1L,CELSR3,MRVI1,NRN1,F3,GPM6B,NNAT,OLR1,PCSK5,XRN1,RGS4,ARC,PLEKHH2,RICTOR" Coexpression M1665 "Down-regulated in the cerebral cortex of aged (22 months) BALB/c mice, compared to young (2 months) controls" MSigDB C2: CGP Curated Gene Sets (v6.0) 2.47E-03 1.00E+00 1.94E-02 1.93E-01 17 54 "ATP1A1,EIF4G3,ATP2A2,CCK,SEPT7,CS,DCTN1,DNM1,TUBB3,GABRA1,CPLX1,KCNMA1,MAG,NPTX1,PRKACB,SYT1,CSDE1" Coexpression M2839 Genes up-regulated in a panel of epithelial cell lines by TGFB1 [Gene ID=7040]. MSigDB C6: Oncogenic Signatures (v6.0) 2.48E-03 1.00E+00 1.95E-02 1.93E-01 45 192 "MRTFA,ANK1,CAPRIN2,RGS11,SOCS6,JAM2,TBPL1,AKAP12,NCOR2,ABCG1,CSF1R,CSNK1E,RUSC2,LYPD1,HS3ST2,EDN1,PLEKHA1,TUBB4A,DLC1,FGF1,FOXF2,FERMT2,ARHGAP12,ADAM22,PFKFB3,PIK3CD,SMOX,PMP22,LRP12,SCHIP1,PPP2R2B,PKIA,FAT4,RGS12,CCDC82,SGK1,SMTN,PHLDB1,KANK1,ACSBG1,JMJD6,KHDC1,WNT7A,PMEPA1,JMJD1C" Coexpression 16715129-SuppTable3 Human HeadandNeck_Jarvinen06_325genes GeneSigDB 2.48E-03 1.00E+00 1.95E-02 1.94E-01 63 288 "CLK4,PPFIA1,ALS2,FAM131A,ATP1B3,CACNB2,ENTPD2,CHRNB2,ZFYVE9,SLC4A7,CSNK1E,OSBPL3,PLCH2,PPP6R2,ECE2,EFS,RCSD1,SIRPB1,KATNAL1,SH3YL1,HPCAL4,POMT1,PRELID3A,RAB30,GLS,GRIN1,HTR2A,ICA1,KCNN3,MAN2A2,MBNL1,PPM1L,THYN1,MYH7,OPRL1,PAX6,PENK,MRPS18A,MYH14,MAP6D1,PUF60,SLC6A11,IFT122,CMTR2,MYCBP2,ADHFE1,KLHL7,ZC3H4,TACR1,FBXW11,NSD1,AKTIP,GALNT17,RASD2,NPL,TRIO,NEIL2,VLDLR,NSD2,ZNF138,SPIRE1,PRTFDC1,SLC17A7" Coexpression M2995 Genes up-regulated in B lymphocytes stimulated by anti-IgM: ZFX [GeneID=7543] knockout (2h) versus wildtype (12h). MSigDB C7: Immunologic Signatures (v6.0) 2.50E-03 1.00E+00 1.97E-02 1.95E-01 39 161 "AS3MT,ESYT2,GAS7,N4BP2L1,DST,C1QC,CD38,CCPG1,ADGRG1,DZIP3,CX3CR1,TOX,TBC1D5,ZEB2,SRGAP3,FRY,PLEKHA1,FOXO3,ST6GALNAC3,FYN,ZMAT1,FAM120B,GUCY1A1,TOX2,KIF5C,ZFYVE27,PENK,SERPINI1,SEPT4,PACSIN1,PPM1B,PTPN13,ARID4A,PRR5L,CHD9,ATF7IP,SYT11,TRPS1,ZDHHC20" Coexpression M9814 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to anaplastic thyroid carcinoma (ATC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.53E-03 1.00E+00 1.98E-02 1.97E-01 22 77 "ALCAM,ANK3,ARHGEF7,SLIT2,QKI,CREB5,DMD,ZNF638,KCNMA1,MAP2,PLEC,KANSL1,SAMD9,SYTL2,ROBO1,ATXN1,SHANK2,TAB2,PLCB1,ANKRD28,DICER1,PMEPA1" Coexpression M2681 Genes down-regulated in myometrial cells over-expressing a shortened splice form of ATF2 [Gene ID=1386] gene. MSigDB C6: Oncogenic Signatures (v6.0) 2.54E-03 1.00E+00 1.98E-02 1.97E-01 44 187 "SERPINA3,ADORA3,TRMT9B,KCNAB2,DGKD,BMPR1B,IL33,CCK,CLGN,CRLF1,NPIPA1,HAPLN1,SNCAIP,TENM4,PDE4DIP,SDC3,GPRASP1,DAPK1,KLHL3,KBTBD11,ENO2,ABCA8,EFEMP1,ST3GAL6,IQCG,SORBS1,PNMA2,STMN2,PADI2,HSD17B1,KCND2,LAMA2,MN1,ADAM22,PLXNB1,CDIP1,LAMA1,PID1,SLC1A3,NXT2,TPD52,DNAJC12,VAV2,PLSCR4" Coexpression 15955831-SuppTable1 Human StemCell_Komor05_21genes_ErythropoieticDifferentiation GeneSigDB 2.54E-03 1.00E+00 1.98E-02 1.97E-01 9 21 "ANK1,CALB1,CD86,CTH,VSIG4,SMOX,PSAT1,RAP1GAP,TMOD1" Coexpression M2862 Genes in the blue cluster of protein kinases distinguishing between luminal A and basal breast cancer subtypes. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-03 1.00E+00 1.98E-02 1.97E-01 9 21 "BMPR1B,DCLK1,ERBB4,FGFR3,RET,NEK11,EPHA10,STK32B,MAP3K12" Coexpression M7176 Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing monocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-03 1.00E+00 1.98E-02 1.97E-01 9 21 "CH25H,HOMER3,CRHBP,CSF1,EPS8,HPGDS,NEFH,ARHGEF12,UCHL1" Coexpression M3835 Set 'Sox2 targets': genes upregulated and identified by ChIP on chip as SOX2 [GeneID=6657] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-03 1.00E+00 1.98E-02 1.97E-01 142 734 "SDE2,ADAR,ADD3,CDC7,AP2A1,OSBPL1A,SEMA6A,ALCAM,OGT,CDC42BPA,PARG,CACHD1,APP,CDC14B,RASL11B,TMEM108,ALDH7A1,RIPK1,BMP7,CA4,CACNA1A,CACNA2D1,SPAG9,CDH2,LARGE1,FOXN3,B4GALT6,CNOT8,BTF3L4,RBM39,RNF14,FEZ1,CSNK1E,VCAN,CTH,PUM1,HDAC9,TCAF1,KIF26A,TMEM170A,ZEB2,HEPH,COPS7A,LYPD1,GUCD1,SMG7,MED12,DNM2,DPYSL2,ACOT8,DTNA,AASDH,KLHL5,SUGP2,APH1A,EGR3,EIF4G2,ELAVL2,ING4,ERBB2,PIPOX,FGFR1,UFM1,TRIM16,OGA,TNRC6A,MSL3,KCNMB4,DIDO1,FICD,LINGO1,HAS2,HNRNPK,IFI16,KCNN2,PAXBP1,VWA5A,HECTD2,XRRA1,MOBP,SCG3,MYO9A,PCSK5,ENPP2,CDK14,MINDY2,PPM1B,PPP2R5C,CEP41,ANKHD1,PTN,ZIK1,ZSCAN2,PPP2R3C,C1orf54,RASGRF2,RGS10,RIC8B,RPL15,ZNF331,RMI1,DGLUCY,SALL1,SFPQ,SH3GL3,FBXO11,NAXD,MAST1,RCOR3,SNRPN,SOX2,KDM3A,SP2,LHPP,ZC4H2,NCDN,KANK1,FAM168A,TAL1,FBXW11,TCF7L2,OBSL1,LEFTY2,SLC44A1,TIMP4,CBX5,FAM124A,TPM3,SGK3,UBC,UGT8,ZIC1,ZIC2,ZIC3,SPIRE1,SMARCAD1,MAP3K12,URM1,FIP1L1,FZD3,MRPL47,KAT6A" Coexpression M19304 Genes up-regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.54E-03 1.00E+00 1.99E-02 1.98E-01 4 5 "GBX2,PAX6,SOX1,ZIC1" Coexpression 16166195-TableS1a Mouse Testicular_Denolet06_509genes GeneSigDB 2.55E-03 1.00E+00 1.99E-02 1.98E-01 73 343 "NR0B1,ANK3,GAS7,N4BP2L1,OSGIN2,CALM1,CCK,CDH2,CDO1,B4GALT6,CLU,CLTB,TJP2,SLC4A7,AHCTF1,AKAP12,GPSM1,SPOCK2,ELMO1,RABGAP1L,ARRDC4,TSPAN5,TUBB3,ST3GAL6,DPYSL4,B4GALNT1,MTHFD2,ACSS1,STARD10,MYOZ2,HTATSF1,PCSK1N,GPT2,GPD1,INPP5B,LIFR,LYPLAL1,TM6SF1,MXI1,SLC11A2,CLDN11,PFKFB2,PFKFB3,ZFYVE21,SMOX,PLP1,RC3H2,PSAT1,MAPK9,ELOVL2,SPDL1,PTPRE,ATXN2,HSPA4L,SGK1,FAM102A,CPEB3,FNDC3A,CLSTN1,SLC22A4,KDM4B,SRPK2,LRRC4,ANKRD28,PJA1,ACSL6,ATP13A2,TNNT1,SLAIN1,TBC1D15,TUBA1A,CIAPIN1,ST8SIA2" Coexpression 15257931-SuppTableA Human Leukemia_Teuffel04_726genes GeneSigDB 2.59E-03 1.00E+00 2.02E-02 2.01E-01 112 562 "CLK4,ACTN1,AP2A2,OSBPL1A,SEMA6A,OGT,GAS7,BCAS1,APP,PDXK,PDE8B,ATP1B3,RIPK1,CACNB2,CARS,CNOT8,ZFYVE9,NRXN2,NMT2,CLTB,TJP2,SUMF2,PREPL,ENTPD4,CRMP1,SOCS5,GREB1,ARHGEF4,CTNND1,PUM1,ARHGAP32,HDAC4,RIMS3,POM121,SRGAP3,PLXNC1,ING4,RABEPK,CDKL3,NRN1,FCGRT,UBE2E3,FYB1,AHCYL1,GALC,ZNF274,IQGAP2,GART,NFU1,GLDC,MSL3,FERMT2,GPM6B,PCLO,ACOT7,AGFG1,IDH3A,IL6R,IL6ST,JAK1,KCNN1,STMN1,SMAD1,MSR1,TAGLN3,CNOT4,NOVA1,NRGN,GPSM2,PRKCB,MAPK3,SIDT1,DEF8,SNRK,PTK2,RIPOR1,NKAIN1,RERGL,CCDC25,RPS6KA2,STK32B,RYR1,SCN3A,SHMT2,EPN2,SEPHS1,SHANK2,SMARCA4,MAPKBP1,KDM4B,SOX11,ZNF423,RBM26,RGL1,DIP2A,KANK1,ANKRD28,TBL1X,KIAA0930,TCF7L2,ARHGEF12,ATP13A2,RIMBP2,KCTD2,TNS1,TRIO,PDSS1,SH3GLB2,PRDM2,PARP6,TRIM16L,JMJD1C" Coexpression M17572 Genes down-regulated in the luminal B subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.59E-03 1.00E+00 2.02E-02 2.01E-01 112 562 "TTYH1,NDRG2,ADCY2,ADD3,ADGRF5,SRPX,BBOX1,BIN1,ANK2,APBA2,APP,PROM1,DST,IL33,CALB2,CH25H,CD38,CRLF1,CHI3L2,CLCN4,COL9A3,TCEAL2,SNCAIP,CSF2RA,VCAN,PPP1R16B,RIPOR2,SV2B,CHRDL1,DMD,DOCK2,RCAN1,DTNB,EDN1,EGFR,PCOLCE2,ELN,EPB41L2,RASGRP2,EXTL1,ABCA8,FABP7,EFEMP1,FHL1,UBE2E3,FOLH1,KHDRBS3,NSG1,MPP6,FYN,GAD2,LYVE1,FERMT2,GPM6B,GPR19,FAM107A,GUCY1A1,WIF1,PADI2,SCRG1,IFI16,IGF1,ITGA7,KIT,L1CAM,MID1,MT1M,MYCN,NINJ2,NPTX2,PAX6,PDGFRA,ENPP2,CYTL1,PFKP,SERPINE2,PIK3CD,PLIN1,PLTP,PSAT1,PPP1R1A,PRKCB,KLK6,PTCH1,PTN,PTPRZ1,PTX3,SLC6A15,NUDT11,ZNF532,TMEM100,WLS,RYR1,S100B,SELL,MRAS,FERMT1,FHOD3,ST8SIA1,DZIP1,INAVA,SOX10,SOX11,TCF7L2,TRIM2,GPR161,TIE1,LILRA4,UGT8,ZIC1,ITM2C,HRASLS" Coexpression M10431 Genes down-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.61E-03 1.00E+00 2.04E-02 2.02E-01 47 203 "ACADM,AP1B1,SRPX,APLP1,NCOA1,C5,CACNA2D1,CLDN10,RGN,CDO1,CLU,CTNND2,TOMM20,DMD,DMPK,DPP6,DENND4A,GATM,GJB1,GRB10,ICA1,IL6ST,KCNJ4,LSS,MAT2A,SHC3,MEST,MXI1,NRCAM,NTRK2,NUCB1,NUCB2,PAX6,MAPK9,PTH1R,PTPRN,PTPRN2,RDX,RNASE1,ROM1,SGK1,SLC20A2,SNRPN,ITPRID2,KANK1,ZNF32,KCNAB1" Coexpression M11896 Genes whose expression profile is specific to Cluster IIa of urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.63E-03 1.00E+00 2.05E-02 2.04E-01 35 141 "ALCAM,DDX3Y,CFL2,CNN3,ARMC8,WHRN,FAM171B,CYBB,DPYSL2,RCAN1,RCAN2,ACSL4,ZMAT1,NEK6,IQGAP2,GSN,PSIP1,RASSF8,TOX2,KIF2A,LIG4,LMO2,MBNL1,MYO5A,PMP22,SGK1,ST6GAL1,CDK5RAP2,PALLD,SON,STXBP1,FAM200B,TMOD1,TRPS1,ZFAND5" Coexpression 17671232-TableS2a Human Lymphoma_Wouters07_223genes GeneSigDB 2.65E-03 1.00E+00 2.06E-02 2.05E-01 42 177 "ADCY6,BIN1,PPFIA1,PPFIA3,BCL7A,SYNJ2,ADGRG1,CSNK1E,ARHGAP32,TOX,FEM1B,EVL,SEMA4D,FYN,GRIK5,KIF3A,GUCY1B1,MUM1,KLF12,ELOVL5,HMGCR,KLHL23,GIT1,PCBP3,PALM,SERPINE2,LRP12,PTPA,LIMS2,ZCCHC24,SPTAN1,SRPK2,ZC4H2,FAM168A,SIN3B,ZEB1,OBSL1,SLC35G2,ATP13A2,TPM1,ZNF711,ZNF177" Coexpression 17711579-Figure1 Human Testicular_Duale07_100genes GeneSigDB 2.65E-03 1.00E+00 2.06E-02 2.05E-01 23 82 "USP6NL,USP3,HEYL,GPR61,TNK2,ANKFY1,FYN,MEGF10,PRDM5,IL6ST,NF1,PDE3B,ARHGEF10L,SLC25A36,ZNF334,GKAP1,DMXL2,PCDHB9,TRIO,TRO,PCDH20,ZFP37,NAV3" Coexpression M9065 Genes up-regulated in C2AS12 cells (myoblast) by IGF1 [GeneID=3479] vs PDGFB [GeneID=5155]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.65E-03 1.00E+00 2.06E-02 2.05E-01 23 82 "PPFIA4,USP2,MYOM2,DCLK1,CNR1,IFFO1,DUSP27,GATM,GPT2,MYH3,NCAM1,PGAM2,TMEM38A,PKIA,PYGM,SOX8,RYR1,SMTN,DAAM2,TNNT1,TPM1,TPM2,FNDC5" Coexpression M19849 Genes down-regulated in T helper cells (defines as CD4+) isolated from patients with mucosis fungoides compared to those from normal control donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.66E-03 1.00E+00 2.06E-02 2.05E-01 30 116 "ACTN1,ADD3,OSBPL8,FUBP1,CALM1,CD81,CDC42,NPIPA1,ZBED5,SYNCRIP,EVL,MALT1,IL6ST,KTN1,NACA,NAP1L1,NUCB2,OLA1,PPP3CC,PTPRO,TUG1,RBM26,MPRIP,VAMP1,DDHD2,TPD52,METTL3,TTC3,PITPNB,HNRNPA3" Coexpression 16818636-TableS1 Human Leukemia_Takeda06_172genes GeneSigDB 2.67E-03 1.00E+00 2.07E-02 2.06E-01 31 121 "GAS7,CACNA1G,CA8,HIP1R,PDE4DIP,TOX,DYRK1A,EDN1,LPAR6,PCOLCE2,CALCRL,FAM198B,PCDH17,IL6R,OLFM3,P2RX7,PCDH9,SERPINI1,PLCL1,PTPN13,FIGN,SLC25A36,SCN2A,SYBU,SLC1A6,LIMCH1,SPTAN1,DMXL2,TEX15,P2RY12,FRMD6" Coexpression M10967 The metastasis gene signature: genes up-regulated during metastasis of NSCLC (non-small cell lung carcinoma) tumors to bone. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.67E-03 1.00E+00 2.07E-02 2.06E-01 7 14 "THSD7A,ABCG2,MICAL2,SUSD5,TAOK3,SNAP25,TCF4" Coexpression M2096 "Genes down-regulated in the RCC4 cells (renal cell carcinoma, RCC) expressing VHL [GeneID=7428] mutants Type 1 and 2B (associated with RCC) but not those of Type 2A and 2C (not associated with RCC)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.67E-03 1.00E+00 2.07E-02 2.06E-01 7 14 "MTMR3,RHOBTB1,SEC31A,SNRPN,PALLD,ITGB3BP,MPPE1" Coexpression 15466177-Figure4 Human Neuroblastoma_Wei04_24genes GeneSigDB 2.67E-03 1.00E+00 2.07E-02 2.06E-01 7 14 "CNR1,KLRC2,MYCN,ROBO2,SOX6,BTBD3,ARC" Coexpression M16097 "Genes whose CpG islands are hyper-methylated in the NB4 cell line (APL, acute promyelocytic leukemia) compared to PBMC (normal peripheral peripheral blood mononuclear cells)." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 20 68 "ZNF582,VSTM2A,DNAJB5,SUSD5,ZNF582-AS1,EPHA5,GAB1,TTBK1,KCNA4,MMP16,TRHDE,IRX1,CTXN2,COLGALT2,SSTR2,TAC1,ADGRL3,PCDHGB6,RUNDC3B,CADM1" Coexpression 18490921-Table3 Human Breast_Bertucci08_75genes GeneSigDB 2.68E-03 1.00E+00 2.07E-02 2.06E-01 20 68 "ADCY2,SPARCL1,SCARB1,FOXN3,ELN,ERBB2,RCSD1,ALDH1L1,IGF1,JAK2,ADAM11,NRGN,PIK3CD,GDPD2,CCDC82,NECAB1,TMEM136,TEK,TF,TNFRSF1B" Coexpression M8414 Genes up-regulated in spleen CD8+ dendritic cells versus bone marrow monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 46 198 "DPF1,ADAR,ARSE,CADPS,PDE8B,ATP2B1,LRBA,PCYT1B,SLC4A7,CRY2,CLIP3,ABCG1,OSBPL3,RUBCN,USP6NL,KIAA0087,SACS,IGSF6,EFS,TUBB4A,FLT1,PRELID3A,GAB1,SRCAP,DIDO1,GRIK2,BTN2A1,GSN,DDX19B,HLF,KCND2,STMN1,MITF,NCF2,RDX,ERI2,KCTD17,ROM1,RORB,MRAS,ZNF423,STXBP1,KIAA1107,TPM1,PITPNB,CLIP2" Coexpression M10014 Genes up-regulated in macrophages: control versus glioblastoma conditioned. MSigDB C7: Immunologic Signatures (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 46 198 "NDRG2,ARRB1,EIF4G3,BCS1L,KRIT1,FOXN3,MYRIP,PHF19,MAMLD1,FARSB,EDIL3,EDNRB,OPTN,EPB41,ABCA8,RACK1,ABLIM2,DNER,GHR,GRIK3,GRM8,FAM19A2,UBE2QL1,HNMT,MSL1,SCIN,KCNK2,SAMD5,ZNF92,PCSK1,PRRX1,PPP2R2B,FITM2,SAMD9,PLPPR1,RASGRF2,FIGN,RTN1,CASC3,RIMS1,NACAD,KLHL7,VAMP1,TAC1,LRTM2,TCEAL7" Coexpression M6272 Genes down-regulated in cortical thymic epithelial cells (cTEC) versus thymic dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 46 198 "RBM10,RNF157,PI16,APOC2,AMER3,SGCE,HAP1,FMNL3,STOML1,CP,CX3CR1,ZNF804A,ARRDC4,FAM78B,RASGRP1,RABEPK,FHL1,SCARA3,MEX3B,FAM49B,B4GALNT1,RND1,COPS8,GPT2,KCNH1,MDM4,NINJ2,NPTX1,OLR1,PAH,MBOAT7,PRKCG,GAL3ST4,RGS4,ROM1,SEC14L1,EPN2,NFASC,SAMSN1,TMEM121,WBP2,KCNT2,LYPD6,PMEPA1,ITM2C,PLD4" Coexpression M8165 Genes down-regulated in HEK293 cells expressing: wildtype NOD2 [GeneID=64127] versus mutant NOD2 [GeneID=64127]. MSigDB C7: Immunologic Signatures (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 46 198 "ZSCAN18,CACNA1G,CACNA2D1,SLC25A14,RGN,SLC22A6,AKAP5,ABI3BP,CPS1,RIMS3,SNAP91,EGR3,ST3GAL6,GAD1,ARPP21,GCK,HTATSF1,GRM1,HRH3,IL6ST,KCNK2,MAP2,MYL3,PAX6,PFKFB4,LRP12,PSAT1,SDK2,MINDY2,TMEM104,CCDC40,ZCWPW1,FEZF2,RIT2,PPM1E,FHOD3,IFT122,ZHX3,ACSL6,TRIM2,TEK,TLL2,RIMBP2,TRO,KLC2,ANKS1B" Coexpression M4676 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus CD4 [GeneID=920] effector memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.68E-03 1.00E+00 2.07E-02 2.06E-01 46 198 "TKTL1,ADRB2,PDZD4,AMPD3,ATP2A2,ATP2B1,BARD1,CHN1,FBXO7,NECTIN3,FEZ2,RABGAP1L,DPYSL2,EPS8,FLT1,FAM49B,CSPG5,LYVE1,RAPGEF1,FAM19A2,DDX19B,LIMS1,MIR4697HG,NASP,PFKFB3,PIK3R1,POLR2F,PPP3CC,PTPN13,PLEKHB2,FBXW7,KIF21A,SLC6A1,FAIM2,UHRF1BP1L,NEK4,SYT11,PCDHGA10,PCDHAC2,TNFRSF1B,TP53BP1,FLRT2,KCNK12,PMEPA1,ST7,RTN4" Coexpression M16108 "Genes down-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.71E-03 1.00E+00 2.09E-02 2.07E-01 41 172 "MTUS1,PPFIA4,CADPS,ASCL1,ALDH7A1,LINC00847,LOC730101,CHGA,CLCN4,TENM4,VCAN,HDAC9,DBI,ELMO1,PLPPR4,CHRDL1,LINC00599,MFSD10,ETV1,RAPGEF4,ICA1,KCNMA1,STMN1,LMO1,MXI1,MYCN,NELL1,NME4,PDGFRA,PFKP,SCHIP1,LRRN3,PTX3,RGS4,RPS6KA2,RTN1,RPH3A,LMO3,CBX5,CADM1,VSNL1" Coexpression 17449903-Table2 Mouse Skin_SuryoRahmanto07_50genes GeneSigDB 2.72E-03 1.00E+00 2.09E-02 2.08E-01 16 50 "DDR1,ARHGAP24,DCT,FYB1,GLS,GPM6B,PCLO,LSAMP,MBP,MEF2C,PDE4B,TMOD2,SNAP25,TNIK,TCF4,FMN2" Coexpression 11920564-Table5b Human Lymphoma_Islam02_31genes GeneSigDB 2.74E-03 1.00E+00 2.10E-02 2.09E-01 10 25 "RGS20,CHI3L2,CNN3,IPCEF1,USP6NL,DPYSL2,GABBR1,TUBB2B,SELL,TUBB2A" Coexpression 15365572-Table4 Human Esophagus_Fukuda04_28genes GeneSigDB 2.74E-03 1.00E+00 2.10E-02 2.09E-01 10 25 "BCL7A,CBLN1,CHI3L2,KMT2C,GPD1,PCDH9,MAPK3,LEFTY2,ZMYND8,NSD2" Coexpression 15808516-Table2 Rat Lung_not_cancer_Balharry05_31genes GeneSigDB 2.74E-03 1.00E+00 2.10E-02 2.09E-01 10 25 "CHRNB2,CNR1,SV2B,GABRG2,GRIA2,GRIK3,NR3C1,HTR5A,SLC1A2,SSTR2" Coexpression M7429 "Genes down-regulated in T98G cells (glioma, express MGMT [GeneID=4255]) by carmustine [PubChem=2578] at 24 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.75E-03 1.00E+00 2.11E-02 2.10E-01 12 33 "ACTN1,ADRA1B,COL9A1,SPEG,GABRA2,GPR37,MSR1,MED1,RGR,RIT2,ICAM5,SLC30A3" Coexpression 15886297-Table1 Human Endometrial_Takai05_36genes GeneSigDB 2.75E-03 1.00E+00 2.11E-02 2.10E-01 12 33 "CLU,TMEM59L,SLC4A8,ABCG1,FAM131B,SPOCK3,DPYSL4,SORBS1,TPPP,ITGA7,TMEM255A,SUSD4" Coexpression M11405 Candidate genes in the regions of copy number loss in gastric cancer cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.79E-03 1.00E+00 2.14E-02 2.13E-01 11 29 "ADAM23,RCBTB2,MDGA2,RNASEL,SH3GL2,FNDC3A,KANK1,TEK,VLDLR,MDH1B,CAB39L" Coexpression M8182 Genes down-regulated in B lymphocytes immunized with: imiquimod [PubChem=13982876] versus monophosphoryl lipid A and imiquimod [PubChem=13982876]. MSigDB C7: Immunologic Signatures (v6.0) 2.81E-03 1.00E+00 2.16E-02 2.14E-01 39 162 "ADRB2,SNX32,AK2,DPY19L3,BTK,FEZ2,RIPOR2,USP3,PAN3,POLR1B,WDR83,ATP6V1H,TBR1,GABBR1,SESN1,DBF4,RAB30,GPD1,CECR2,RAPGEF1,IRF8,TJAP1,JAK2,SH3KBP1,MARCH1,RAP1GDS1,EXD2,SATB1,TRA2B,SLA,GKAP1,SS18,ATMIN,USP22,SIRT1,SGK3,SF1,ZFAND5,CSDE1" Coexpression M5793 Down-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.81E-03 1.00E+00 2.16E-02 2.14E-01 48 209 "ADD3,AXIN2,OSBPL8,CNTNAP1,APP,ATP6V0A1,CCPG1,FADS2,FAM171B,CSF1,CST3,MAGI2,DNM1,DPYSL2,KLHL5,EGFR,ETV1,FAM198B,FCGRT,KIAA1109,GABBR1,GATM,SESN1,GLS,PRUNE2,GSN,IRAK3,IL6ST,ITPKB,KIT,ARHGAP12,LSS,MBP,MXI1,XRN1,PLXNB1,WBP1L,REV3L,SLC25A36,ELP2,SATB1,PDZRN3,ZCCHC24,ANKRD12,ZMAT3,ZNF106,WBP2,RNF146" Coexpression 18625725-TableS1 Human Breast_Wang08_271genes_Alk5(T204D) GeneSigDB 2.84E-03 1.00E+00 2.17E-02 2.16E-01 54 241 "KCNH8,ADCY2,KIAA1211,ADGRF5,PDZD4,RGS20,CADPS,FGF17,KALRN,CD38,CDR1,B4GALT6,NRXN3,CCDC151,SMARCAL1,CRYM,CHD5,CALY,SIRPA,TSPAN5,ELAVL3,EPB41L1,TUBB4A,PPP1R1B,PDLIM5,GABRA3,RAPGEF4,GRID1,UBE2QL1,HNRNPK,SCIN,L1CAM,SYTL4,NPY,SERPINI1,PKD1,PLCL1,MBOAT7,PACSIN1,SH3KBP1,RANBP3L,PRKAB2,SCNN1D,KIF27,SCG5,CPEB4,LIMCH1,FNBP1,CLSTN2,ADGRL3,SYNE1,RELL2,TPD52L2,ZNF346" Coexpression M16596 Up-regulated genes characteristic for autonomous thyroid adenoma. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.86E-03 1.00E+00 2.18E-02 2.17E-01 21 73 "CARNS1,CACNA1D,CDH2,TMEM59L,DBN1,TIAM2,PARD6A,DLG4,DUSP9,FGFR3,GNAO1,IGFBP1,KCND2,MIA2,PCSK2,PRKCB,RAB3A,ST6GAL1,SNAP25,NMNAT2,FLRT1" Coexpression 18280641-table2 Human Prostate_Sigala08_76genes GeneSigDB 2.86E-03 1.00E+00 2.18E-02 2.17E-01 21 73 "ABAT,CLOCK,ABCG1,DCAF8,HSPA12B,AGAP3,RAPGEF6,DISC1,KLRC2,LMO2,PLEC,TNPO2,PPARA,EPN2,MBD5,FNBP1,SLC44A1,TMPO,TRIO,KCNT2,KLHDC1" Coexpression 19139136-TableS2 Human Prostate_John-Aryankalayil09_450genes GeneSigDB 2.87E-03 1.00E+00 2.19E-02 2.18E-01 72 339 "IGDCC4,DNAH17,INSYN2B,MYOM1,BARD1,CH25H,CBS,REPS2,CLGN,CLIP3,ERC2,CMTM5,CNIH3,CPEB2,ECM2,FRY,ELAVL2,TNK2,ZNF461,TOMM40L,AMOTL2,SCARA3,ZMYND15,JKAMP,NPTN,FAM19A2,ADAMTS6,TOX2,HMGB1,HP,HSP90AA1,ICA1,IL6R,STMN1,SFXN5,MAP2,NASP,NRGN,OGDH,CLDN11,GLIPR1L2,PCSK1,PDE2A,BEST3,ANLN,NECAB2,SLC36A4,PILRA,BCAS3,LRRC49,LAMA1,ELOVL2,PTPRB,MARCH1,ATP8B4,RMI1,SEMA6D,ASIC4,ASRGL1,SH3GL2,NTNG1,SLC8A3,SLN,ARHGAP26,SPTAN1,NSFL1C,MCF2L,TPCN2,TK2,ADAMTS9,TMEM178A,FRMD6" Coexpression 18537972-TableS4 Human Leukemia_San Jose-Eneriz08_730genes GeneSigDB 2.88E-03 1.00E+00 2.20E-02 2.18E-01 122 621 "ACTN2,ADCYAP1R1,GRAMD1B,ADRA1D,AP2A2,SEMA6A,KIAA1614,ASPH,N4BP2L1,RGS11,BCL7A,CFLAR,MTMR2,BSN,CAMK2G,CDC27,CDC42,CHRM4,JAM2,CPNE6,CLCN3,TPP1,TMEM59L,FAM149A,CABP1,COL11A2,DZIP3,DCAF8,TM9SF4,TBC1D5,MATR3,BRINP1,HP1BP3,LYPD1,SPOCK3,SGSM2,DMPK,DSCAM,DTNA,USH1C,PHC2,KLHL5,SRRM1,CEND1,CORO2B,ST3GAL6,AGAP2,FLT1,ZNF44,MTHFD2,SRCAP,CYP46A1,ADAM28,LYVE1,GLDC,TOX3,GOLGB1,PCLO,NR3C1,NCKAP1L,BACH2,HMGCL,TLX1,IL12A,KCNMA1,MAPT,MOG,GIT1,PTOV1,MYL3,MYT1,FXYD7,NTRK2,DDR2,PCSK5,PIK3R1,MED1,PPP5C,SPDL1,TUG1,PID1,CCDC40,MYH14,SAFB,SATB1,ZFP2,SEC14L1,SUPT20H,TRA2B,ITSN1,PPP1R9A,DZIP1,SLC6A1,KBTBD4,SLC20A2,ATF7IP,SLCO1A2,SLN,KDM4B,KDM4C,ZNF423,SSTR1,SSTR2,MAPK8IP3,TACR1,TAF9,IQCE,DOCK9,CBX5,ICAM5,PDSS1,TSC2,UBE3A,UGT8,FLRT1,ZIC3,ZNF711,TRIM9,ZBTB38,WIPF2,PAK5,GAN" Coexpression M2764 Genes up-regulated during early stages of differentiation of embryoid bodies from J1 embryonic stem cells. MSigDB C6: Oncogenic Signatures (v6.0) 2.89E-03 1.00E+00 2.21E-02 2.19E-01 43 183 "GPRIN1,ADCYAP1R1,TXNDC16,AMPH,SEMA4G,RASL11B,BCL2L2,BMP7,FMNL3,ABCG1,ECE2,DSCAM,CDHR1,FGF14,NSG1,ACSS1,HPGDS,DIDO1,MAG,MPP2,SESN3,ETFRF1,SERPINE2,PIK3R1,RETREG1,TMEM38A,DRAM2,RAB3IL1,PCMTD2,ARMH4,HES6,LMBRD1,SOX15,DBNDD2,ST5,ZFPM2,THRA,HEY1,ZIC2,ZBTB16,VPS35L,NLRP3,NHSL1" Coexpression M19016 Genes down-regulated in erythroid progenitor cells isolated from bone marrow of patients with Diamond-Blackfan anemia (DBA) and mutated RPS19 [GeneID=6223]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.90E-03 1.00E+00 2.21E-02 2.19E-01 99 490 "NDRG3,NME5,ANK1,GAS7,PDXK,CFLAR,BMP7,DST,OSGIN2,CANX,CAPN3,MAP7,CLDN10,KRIT1,CDC27,CDC42,ZMYM4,IQCK,AHCTF1,NCOR1,NCOR2,ARHGEF10,RIPOR2,PITPNC1,PLEKHM1,RHOBTB1,SMG7,SGSM2,TSPAN5,FEM1B,EEF1D,KLHL5,EFNB3,FAM13A,DCTN4,EIF1,RASGRP2,ZNF589,FGFR1,EFCAB2,CAMKK2,GPR153,ERAP1,TMEM8B,AHDC1,PSRC1,GPR12,GRK4,GSN,CLASRP,AP4S1,PSIP1,ELOVL5,ICA1,KCNN1,MAP4,MID1,ADAM22,HNRNPM,NFYA,KCTD15,RC3H2,POLR2F,C1orf54,RDX,RET,DCUN1D2,RPS6KA2,SH3BGR,SLC11A1,SCMH1,KDM4B,SPATA7,ZCCHC24,ZHX3,UNC5B,SRPK2,APOM,KANK1,PRRC2C,TAC3,WWC1,OBSL1,THRA,TPD52,TPM4,CHST5,SSBP2,VGF,XRCC4,ZNF32,ZNF74,ZNF142,ZNF177,INTS3,WNK1,NT5M,HPS4,ZNF248" Coexpression M6616 Set 'Nanog targets': genes upregulated and identified by ChIP on chip as Nanog [GeneID=79923] transcription factor targets in human embryonic stem cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.90E-03 1.00E+00 2.21E-02 2.20E-01 185 988 "ACADM,ADAR,ADD3,AXIN2,CDC7,AP2A1,OSBPL1A,ALCAM,PARG,CACHD1,CDC14B,IGDCC4,RASL11B,TMEM108,RIPK1,MPDZ,BMP7,CA4,CACNA1A,CACNA2D1,CALB1,SPAG9,RUNX1T1,NFS1,CDH2,LARGE1,FOXN3,B4GALT6,CNOT8,EPS15L1,CNN3,IQCK,COL4A5,ZNF521,PREPL,RBM39,NCOR1,CS,FEZ1,CSNK1E,VCAN,PPP1R16B,FAM131B,TCAF1,KIF26A,TMEM170A,ZEB2,MYEF2,LYPD1,WDR20,USP3,MED12,DNM2,DPYSL2,ACOT8,DTNA,AASDH,KLHL5,SUGP2,APH1A,EIF4G2,ING4,BSCL2,ERBB2,MRPL37,PIPOX,EXTL2,ARMCX1,ACSL4,TOMM40L,FGFR1,FOXO3,SORBS1,USP16,APOPT1,UFM1,TRIM16,SARAF,MPP6,OGA,SALL3,GART,TCERG1,TNRC6A,MSL3,POLL,DIDO1,IL1RAPL1,GSTT2,LINGO1,ATG4C,HAS2,SHISA6,IDH3A,IFI16,KCNN2,VWA5A,HECTD2,MOBP,MOV10,NAP1L2,NODAL,PBX1,ENPP2,CDK14,KCTD15,SMIM7,SLC36A4,DRAM2,MINDY2,PPP2R5C,MAPK8,WBP1L,LRRC49,PTN,ZSCAN32,ZIK1,PEX2,PPP2R3C,RAB5B,C1orf54,RASGRF2,RGS10,RIC8B,RPRD1A,EXD2,ALG9,GSTCD,MRAP2,ADAL,CNTNAP3,RYR3,ZNF331,FAM192A,SALL1,SGK1,SCG5,FERMT1,NAXD,SNRPN,SON,WDTC1,SOX2,KDM3A,SP2,SPART,LHPP,APOM,KANK1,DNAJC9,TAL1,UNC5D,FBXW11,TBL1X,KLHL4,EHBP1,SIN3B,TCF7L2,OBSL1,LEFTY2,SLC44A1,TIAM1,TIMP4,CBX5,HEY2,FAM124A,KCTD2,R3HDM1,RBFOX2,SSBP2,SGK3,UBC,EIF4ENIF1,VLDLR,CFAP298,ZIC1,ZIC2,ZIC3,SMARCAD1,MAP3K12,URM1,KAT6A,PHTF2,RSPRY1,FXR1" Coexpression M2964 Genes up-regulated in natural T reg: wildtype versus non-functional FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 2.95E-03 1.00E+00 2.24E-02 2.22E-01 36 147 "ADRB2,LCORL,IGDCC4,ARNTL,ATP6V1G2,CFLAR,DST,C1QC,CD86,CD38,DZIP3,ZEB2,CEP170,SRGAP3,USH1C,FRY,PHF20L1,FAM120B,SYT17,ZDHHC15,KLRC2,L1CAM,NCOA7,NHLH1,SERPINI1,FAM161B,KIF27,BDP1,GLT8D1,SMOC1,SYNE1,KAT6B,MAP3K12,MPPE1,RSPRY1,NETO2" Coexpression M14142 "Genes down-regulated in the invasive ductal carcinoma (IDC) compared to the invasive lobular carcinoma (ILC), the two major pathological types of breast cancer." MSigDB C2: CGP Curated Gene Sets (v6.0) 2.97E-03 1.00E+00 2.24E-02 2.22E-01 15 46 "ADCY2,SPARCL1,FOXN3,ELN,RCSD1,ALDH1L1,IGF1,ADAM11,PIK3CD,GDPD2,CCDC82,NECAB1,TEK,TF,TNFRSF1B" Coexpression M6978 Genes up-regulated in untreated macrophages: naïve versus tolerant. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ABHD6,PLEKHH1,RNF150,MTUS1,CC2D2A,PDXK,BBS2,LDHD,CNOT8,JAM2,CLU,CDC42BPB,NCOR1,EARS2,LONRF1,MTX3,DMD,CELSR3,EXTL2,TOMM40L,FGFR1,STAU2,FUT9,CPLX2,FUT10,PCLO,PRDM5,SMIM11A,FAM98B,C11orf49,LRP12,TMEM100,RTKN,ZFP2,KANSL3,SLC6A7,SLCO1A2,CXXC4,C3orf70,EXOC7,EHBP1,TCF4,AKTIP,RGMB,TRH,TSN" Coexpression M7228 Genes down-regulated in T cells treated with IL21 [GeneID=59067]: 6h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADORA3,AP2A2,TBC1D14,SRPX,ALS2,WASF1,REPS2,CDC25B,ZBED1,SDC3,RASSF2,RHOBTB1,SORBS3,TBC1D16,FER,ABLIM2,FYB1,GATM,ATF7,VSIG4,RBPJ,AFF1,MYO7A,OGDH,PDPK1,PMP22,CNTLN,GLDN,FOXRED2,ITSN1,ABLIM3,SNCA,SPATA7,FNBP1,ARHGAP26,SAMSN1,LARP4,RGL1,DAAM2,TNS1,PIK3R5,TPD52L2,TRPS1,SSBP2,P2RY12,JMJD1C" Coexpression M3899 Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 16 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ABAT,SORCS1,ADRB2,PARG,APOC2,ATP1A1,RIPK1,TRIM41,CD38,LRWD1,IGDCC3,CP,DAPK1,NR1D2,ABI1,PDCD6IP,RASGRP1,SORBS3,ELAVL3,EFS,CHST15,FDFT1,NBEA,DNER,C1QL1,GK,FUT10,HAPLN2,HP,KCND3,MAG,STRN3,PILRA,EML5,RPL38,SCN2A,MRAS,SLC2A5,TAC1,TRIM2,WASHC4,TF,TK2,UBE2H,USP1,EVI5" Coexpression M9996 Genes down-regulated during primary acute viral infection: B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ABHD6,C3orf14,CASK,ASPH,BBS2,NAE1,CBS,COX4I1,CTH,MYEF2,EXOG,DPYSL2,PCOLCE2,TBC1D16,ST6GALNAC3,CSPG5,SESN1,GK,RAB40B,GPM6A,WIF1,IRF8,LINC00667,LRRCC1,KCNC1,MYBPC1,SERPINI1,FAM216A,FTO,RC3H2,ELOVL2,WLS,ZNF354C,SH3BGR,ST6GAL1,ZNF334,SMARCE1,LMBRD1,USP33,LHFPL4,ZFP90,ZNF23,ZNF32,FMN2,REEP1,GAN" Coexpression M7264 Genes up-regulated in bone marrow-derived macrophages: control versus Listeria infected. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "APBB1,ADGRB3,DST,ZMYM4,CDH18,UBE2L6,FAM189A2,DCAF4,KIAA0586,DAPK1,DBI,DCC,FBXL5,SGK2,PLEKHA1,ZIC4,ZNF589,IQGAP2,GCK,GPR75,GNG3,HMGB1,MEF2C,MID1,SLCO1C1,NRCAM,OPHN1,PGAM2,PCDHB17P,RASGRF1,FEZF2,RET,RGS4,ZNF532,BAALC,PRR5L,RXRA,SH3BGR,PEG10,SSTR2,PHLDB1,ACSL6,PCDHGA10,ZFPM2,TUBB1,SSPN" Coexpression M9589 Genes up-regulated in thymic T reg: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADD2,ALCAM,CDC42BPA,GAS7,DNAH17,CALB2,CDC42,COL9A3,SLC4A7,TBC1D5,MAGI2,POM121,LRRC17,AMZ2,IRF8,LINC00667,ITGAV,IPO5,LIMS1,LMO1,MARK3,MMP16,NEFM,OPCML,SNTG1,GPSM2,RAD17,TMEM100,NEK11,COPZ1,FHOD3,SLCO1A2,ZNF667,IZUMO4,RGL1,WSCD1,USP22,CBX5,TP53BP2,SMUG1,TRPS1,ZKSCAN5,TOM1L2,ANKS1B,HRASLS,ST8SIA2" Coexpression M8386 Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADCY6,PPFIA2,CDC14B,ATP1A3,BAIAP3,NRXN3,CNTFR,CYBB,HDAC9,FRMPD4,DNAH9,EFNA3,EFNB3,SIRPB1,F8,GTF2IRD2,OLFM1,TRIM16,GABRB3,NCKAP1,ERAP1,ATP8A2,GK,LILRB4,GRM7,BTN2A1,GUCY1B1,KCNA6,KIF2A,L1CAM,MAOB,NEUROD2,PDE4A,PRRX1,MAPK4,RAD52,RBBP8,RGS12,HSPA4L,FRMPD1,FNDC3A,SLC2A5,ARHGEF12,TP53BP2,TPD52L2,CAMK1G" Coexpression M6963 Genes up-regulated in plasmacytoid dendritic cells in response to influenza virus infection: 1h versus 4h. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADRB2,OSBPL1A,ALS2,APP,ARRB1,SGCE,KYAT1,FADS2,DLG3,CD99L2,PLXNC1,EPB41,SH3YL1,SORBS1,ERGIC3,AP4B1,GHDC,NCKAP1,ALDH1L1,PPARGC1A,B4GALNT4,PCLO,GRB10,IRAK3,HMGCL,FAAP20,IL11RA,ARHGAP12,SRSF12,AFDN,DBNL,PTOV1,NDP,NPR2,SLC6A15,SGK1,ITSN1,LMBRD1,KDM3A,TROVE2,TEK,BEX4,AMOT,GORASP1,ZNF23,FAM219B" Coexpression M7809 Genes down-regulated in monocyte-derived dendritic cells: control versus SIV infection. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "PLEKHH1,ZNF687,ASTN1,TMEM108,RAB29,CH25H,DCLK1,LY86,AKAP12,ZNF804A,OPTN,RASA4,CACNG2,PNMA2,STARD3,B4GALNT4,ADAMTS6,KCNJ10,KCNN2,PPM1L,DBNL,MYBPC1,NOVA2,PFKFB3,DRAM2,PPP3CA,DPF2,RNASEL,RPE,TMEM100,NEK11,HUNK,SHC4,LMBRD1,PBLD,EXOC7,TAL1,VWC2,WASHC4,PCDHB7,DDHD1,SPHK2,ZBTB38,FSTL5,WNK2,FXR1" Coexpression M5015 Genes up-regulated in comparison of monocytes from LAIV influenza vaccinee at day 7 post-vaccination vesus those from TIV influenza vaccinee at day 7. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "CDK5R1,OSGIN2,BSN,CANX,PRC1,MYOM2,CHM,ABCG1,CS,HIPK3,EPB41,SIRPB1,GMPR2,OLFM1,USP21,CAMKK2,GABRA2,GABRG2,MMADHC,CBX1,GPM6A,HMX1,HPCA,MBP,NEFM,NEFH,PDE3B,SSH1,ZFYVE21,TUG1,RGR,KLHL11,EXD2,RPL15,RXRA,SEMA6D,NLGN1,SOX3,SPATA7,SSTR2,SATB2,DICER1,TMPO,BCL2L13,ZIC1,MARCH8" Coexpression M4970 Genes up-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "GRAMD1B,OGT,APP,CDK5R1,WASF1,MAGED1,ENTPD4,CRYM,PPP1R16B,CYBB,EPHB1,TLR7,ZNF589,FHL1,UBE2E3,LILRB4,GPM6B,DIDO1,IRF8,IDH3A,STMN1,SCAMP5,NFYA,NUCB2,KCNK10,ENPP2,PRKCB,SIDT1,RIPOR1,RGS7,SEC61A2,RPS6KA2,STK32B,SMPD3,SEPHS1,ANKRD36,TEX2,TCF4,CUX2,PCDHGA3,ATP13A2,LILRA4,TPM2,LAMP5,ITM2C,CERS6" Coexpression M4432 Genes up-regulated in comparison of naive B cells versus memory IgG IgA B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "SYT13,AMT,DGKD,MARCH3,CCDC181,MTMR9,ATP6V0A1,BCL7A,DDR1,LARGE1,NIPBL,ST18,GPRASP1,MYEF2,EXOG,SLC12A6,PLEKHA1,LRRC23,CORO2B,GABBR1,RAPGEF6,SESN1,DCLK2,GRK4,BACH2,TJAP1,MAOB,MITF,MMP17,NPY,PCDH8,PCDH9,SATB1,SCN3A,SH3BP2,SLITRK3,SLA,SLC6A8,INTS9,PEG10,SZT2,SMUG1,UGT8,ZBTB16,SLC30A4,ZNF37BP" Coexpression M8428 Genes up-regulated in CD8 T cells: effector memory versus naïve. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "NDRG2,GRAMD1B,AGT,PLA2G4C,DNAH17,ATP2B1,SYNJ2,CFAP410,B4GALT6,QKI,RNF14,SV2B,SV2A,EFNA3,EN2,C1orf61,STARD3,STON1,GRM3,GPR45,HPCA,C2orf72,RBPJ,KCNN3,KIF5A,LIFR,MAG,AFDN,MYL3,NFIA,NNAT,SLC11A2,PIK3C2A,SCHIP1,POU6F1,PTPRH,PTPRZ1,ZHX3,HECW1,RGL1,KAZN,DOCK9,RIMBP2,PRDM2,ST7,SSPN" Coexpression M7708 Genes down-regulated in CD4 [GeneID=920] T cells: tretinoin [PubChem=444795] versus Ro 41-5253 [PubChem=5312120]. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADRB2,MYH7B,DNAH17,CHRD,ATP2B1,ARHGEF7,CHGA,PDE4DIP,USP6NL,G3BP2,MAMLD1,GOLGA7,MTSS1L,AGAP2,ZNF274,SYT17,GLS,CNTRL,NR3C1,GRM1,BACH2,MDM4,NFE2L2,NRDC,ODF2,PFKFB3,ZNF426,RC3H2,SAMD9,RXRA,SFPQ,SCG5,DOCK10,WDR37,BEX1,ZBTB43,ITPRID2,STAU1,JMJD6,CAMSAP2,TP53BP2,UBE2H,UBE3A,CLIP2,PORCN,SCG2" Coexpression M5593 Genes up-regulated in comparison of NK cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "EP400,ARRB1,NCOA1,CACNA1A,CDH8,ZFYVE9,SNCAIP,DPP6,PLXNC1,EPHB1,ADGRV1,CHST15,GABBR1,GAD2,TDRKH,GRIK3,SCRG1,HNMT,LINC00667,KIF5A,LIFR,NCAM1,PILRA,PSD,ACSS3,CCDC40,RNF220,KLHDC8A,PRR5L,RTN1,FRMPD1,URGCP,PREX2,PKNOX2,MYO16,PDZD2,CAND2,HECW1,SRPK2,GSE1,EXOC7,SIN3B,ZNF34,FLRT1,TOM1L2,MVB12B" Coexpression M8415 Genes down-regulated in spleen CD8+ dendritic cells versus bone marrow monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "GRAMD1B,MTUS1,MRTFA,ATP1A2,MYRF,CARS,CDH2,CBARP,COX4I1,CREM,HDAC4,DTNB,PHC2,EFNB3,EIF1,SCML2,FGFR1,FYN,STAG2,GFER,GRM1,HMX1,MIA2,NACA,NCAM1,OPHN1,PLCD1,PPM1B,LRRN3,PRKAR1B,RBBP8,SATB1,SHMT2,ST6GAL1,BTBD3,MAPKBP1,SOX1,IQCE,SYNE1,SIK3,TMOD1,KCTD2,TP53BP2,UBE2H,ZNF184,SLC30A4" Coexpression M9319 Genes up-regulated in day 7 memory B cells versus day 7 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "ADD1,MTA3,RASL11B,RNF182,BSN,MYOM2,ANKRD44,TM9SF4,SNAP91,CPEB2,ARRDC4,YAF2,ABI2,CALCRL,VPS26C,POLK,ERAP1,DNER,SPACA9,GYG1,ZDHHC15,ICA1,INPP1,JAK1,KCNQ3,KIT,NUCB1,PDE1C,PDE3B,SNX10,PLEC,WBP1L,SIDT1,PTPRE,FAM184A,RNASEL,RXRA,ELMO2,MBD5,ST5,ATP11A,ARHGAP9,TJP1,ANKRD24,RUNDC3B,RBFOX3" Coexpression M8421 Genes up-regulated in brain microglia versus spleen CD8- dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "NDRG2,NUMB,ATP1A2,ATP2B1,ATP2B2,MTMR2,CCNT1,CHN1,QKI,RIMS3,DGKB,SV2A,ECM2,SEMA3D,FRY,ERCC2,MPP6,ARFIP1,TOX3,STARD3,STON1,GUCY1A1,GPR45,RBPJ,KCNN3,LIFR,LMO2,LSS,SMAD9,CD200,MX1,MYO5A,NPR2,NPTX1,POLR2F,CNNM2,SP4,EPB41L3,VPS13A,ANKRD12,MTCL1,TNFRSF1B,VSNL1,EVI5,RNF103,ST7" Coexpression M8267 Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 16h. MSigDB C7: Immunologic Signatures (v6.0) 2.98E-03 1.00E+00 2.24E-02 2.22E-01 46 199 "GRAMD1B,NME5,ATP2B2,PROM1,DCLK1,GPR37L1,CLCN4,SLC24A2,RCHY1,CPS1,TOX,SV2A,SGSM2,DOCK2,TVP23A,WASF3,FREM1,TNRC6A,OS9,NKD1,MBNL1,COMMD5,SLCO1C1,PENK,NALCN,TRHDE,TMEM104,RAP1GAP,GAL3ST4,RPE65,SHC4,ZNF365,RADIL,SIRT2,SAMSN1,ACSBG1,COBL,PDLIM2,PSD3,LEFTY2,ZMAT3,UBC,UBTF,SYNC,STMN4,SLC17A6" Coexpression 15665281-TableS2 Human Brain_Wong05_78genes GeneSigDB 3.01E-03 1.00E+00 2.26E-02 2.24E-01 19 64 "ADD3,AGT,SRPX,AQP4,ATP1A2,TJP2,AKAP12,EDNRB,EGR3,OLIG2,KLRC3,LMO2,MBP,NPTX2,OMG,PCSK1,SNAP25,SPP1,ZIC1" Coexpression M2005 Genes with intermediate-CpG-density promoters (ICP) bearing bivalent histone H3 methylation mark (H3K4me3 and H3K27me3) in embryonic stem cells (ES). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.01E-03 1.00E+00 2.26E-02 2.24E-01 34 137 "ADARB2,SLITRK1,ZNF608,CNTNAP1,AQP6,PDE8B,NOL4,NCAN,PHYHIP,SEZ6L2,EXTL1,HSPA12B,CACNG3,GGT7,LOXL3,MCHR1,GRM3,GUCY1A1,IGF1,BRINP3,KCND2,KCNJ5,KCNN3,NRBP2,OPCML,PDE1C,PDYN,PTN,MARCH1,SUSD4,C11orf87,TSPAN11,PCDH20,PAK5" Coexpression M12695 Top 100 probe sets associated with MLL fusions [GeneID=4297] irrespective of the lineage of the pediatric acute leukemia. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.01E-03 1.00E+00 2.26E-02 2.24E-01 22 78 "AK2,ZSCAN18,PROM1,FEZ1,ZEB2,SIDT2,ZNF274,GPM6B,LILRA1,ITGA7,MBNL1,MEIS1,MYO6,PNMA8A,SCP2,PALLD,GLT8D1,CLASP2,MICAL1,VLDLR,LAMP5,JMJD1C" Coexpression 18927307-tableS4 Human Colon_Allen08_124genes GeneSigDB 3.01E-03 1.00E+00 2.26E-02 2.24E-01 22 78 "KRIT1,NCOR1,CDON,FARSB,YAF2,PAN3,DLC1,UBE2E3,DCTN2,GART,GK,MBNL1,MBP,FTO,PPP3CA,PTPRG,SETD5,POGZ,ANKRD28,TCF7L2,WASHC4,DDHD1" Coexpression 16728981-SuppTable2 Human Leukemia_Frank06_128genes GeneSigDB 3.04E-03 1.00E+00 2.28E-02 2.26E-01 29 112 "ADCY6,AMT,PROM1,SCARB1,LARGE1,TBRG4,AKAP7,CHD1L,TUBA8,STON1,GRIN1,IDH3A,KCNQ2,NEFH,PDE1B,ENPP2,NLE1,RPE65,RPH3A,ZNF667,SEPT8,ZEB1,R3HDM1,TRH,HSPBP1,XPO1,ZIC1,ZNF154,ZXDA" Coexpression 20140255-TableS1 Mouse EmbryonicStemCell_Romito10_172genes GeneSigDB 3.05E-03 1.00E+00 2.28E-02 2.26E-01 32 127 "APBB2,KIF1A,BSN,NGB,CHRNA4,ST8SIA3,CHST15,CAP2,SGIP1,EFCAB2,GFRA2,GPD1,PLPP7,HAS2,BTBD17,MEIS2,MPP2,PBX1,ENPP2,PFKFB3,FXYD1,DUSP15,STK32B,EMID1,SST,PLCB1,ARHGAP9,ITGB3BP,CDK20,PITPNB,SCG2,TMEM163" Coexpression M485 Genes up-regulated in CD4 [GeneID=920] T cells from healthy donors: resting versus nitric oxide [PubChem=145068]. MSigDB C7: Immunologic Signatures (v6.0) 3.05E-03 1.00E+00 2.28E-02 2.26E-01 32 127 "ADARB2,ADCY2,KCNT1,UPRT,PHYHD1,SEC24C,CMTM5,BRINP1,DUSP27,FGF13,CAMSAP1,DPYSL4,CBX1,LRRTM1,KCNC2,KCNJ9,CNTN3,MAPK4,PRODH,SLC25A41,MRAP2,KCNIP2,ZFP2,NTNG1,PBLD,SYP,RALYL,PCDHB4,TRH,PRR18,ZBTB14,FZD3" Coexpression 17332353-Table2 Human Breast_Huang07_161genes GeneSigDB 3.05E-03 1.00E+00 2.28E-02 2.26E-01 32 127 "PLEKHH1,KIAA1324,EPB41L5,CA12,CALM1,CAST,SCARB1,CHRM1,EPS15L1,ABCG1,SOCS5,GREB1,MYEF2,EGFR,F3,UBE2E3,ZNF559,STARD10,SPIN1,ICA1,IFI16,INPP1,MAPT,SH3KBP1,ARX,SLC1A2,ST5,POPDC3,CBX5,TPD52,TRPS1,SLC38A1" Coexpression M8174 Genes down-regulated in HEK293 cells at 2h after stimulation by muramyl dipeptide [PubChem=11620162]: over-expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 3.05E-03 1.00E+00 2.28E-02 2.27E-01 31 122 "SYN3,ADCYAP1R1,CNIH2,VSTM2A,MYOM2,HEPH,TMEM130,DLG2,GRIN3A,RAB39B,CALN1,CELSR3,GABRG1,CPLX2,PCDH11X,GNAL,BVES,KCND3,HECTD2,NAT8L,MARK1,SCG3,KSR2,SYNDIG1,PAQR6,KCNIP3,SH3GL3,CLSTN2,RHBDL3,NDRG4,SHD" Coexpression M6518 Genes up-regulated in epithelial cells (6h): untreated versus interferon alpha and IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 3.06E-03 1.00E+00 2.28E-02 2.27E-01 45 194 "ACTN1,METAP1D,FMNL2,AXIN2,GOLGA7B,CDC25B,CHN1,RIPOR2,PHF19,KLHL3,SORBS3,FABP7,NBEA,DLL3,NEK6,MSL3,RNFT2,IL6R,IL6ST,DIPK1A,ITPKB,MAT2A,SESN3,NELL2,OGDH,SERPINE2,ANKRD16,SLC26A11,PTK2,ZNF793,BEND5,NUDT11,ELP2,SELL,RASA3,IGSF9B,MYCBP2,CEP68,DMXL2,PMS2CL,THBS4,RGMB,WNT7A,ATP6V0E2,NLRP3" Coexpression M2728 Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v6.0) 3.06E-03 1.00E+00 2.28E-02 2.27E-01 45 194 "ABHD6,OSBPL1A,CAPRIN2,ASPH,RASL11B,MTMR2,SGCE,CAST,JAM2,NMT2,MICAL2,RCAN1,GNE,OPTN,FAM13A,EGFR,ACSL4,FGF1,SCARA3,KHDRBS3,FYN,ERAP1,MALT1,FERMT2,GPR37,GRB10,SLC2A6,L1CAM,CDK18,PDE4D,SERPINI1,MORC4,ZNF331,ANKRD6,PEG10,ARHGAP26,DBNDD2,KLHL7,SYNE2,TNNT1,NPL,TUBB2A,UGT8,SCG2,NAV2" Coexpression M7943 "Genes up-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999] and IL4 [GeneID=3565]." MSigDB C7: Immunologic Signatures (v6.0) 3.06E-03 1.00E+00 2.28E-02 2.27E-01 45 194 "GRAMD1B,UNC79,APP,CDK5R2,CAMK2A,FOXN3,CREM,FEZ1,MYADM,TBC1D5,TOMM20,CEP170,POM121,SACS,EML1,ABCA8,AMZ2,FCGR1B,BRPF3,KCNMB4,GRIN2C,MGC16275,HSF2,IFI16,ITPKB,ZNF667-AS1,AQP11,POC1B,KCNK10,PGAM2,DRAM2,PPP2R2B,CCDC40,RPRD1A,STX1B,LINC00461,CCDC92,ABLIM3,SAMSN1,FGD4,ZC3H4,AZIN2,FLRT2,PLEKHH2,ZNF17" Coexpression 15902281-TableS1b Human Leukemia_Schoch05_1693genes GeneSigDB 3.11E-03 1.00E+00 2.32E-02 2.31E-01 147 767 "GRAMD1B,AP2A2,C1QTNF4,CEP126,BBOX1,SYT13,AMPD3,USP28,PPFIA1,APBB1,DGKZ,API5,MADD,ARNTL,ARRB1,STK33,ATM,MTMR2,GYG2,BRSK2,CARS,CCKBR,USP2,CD81,UBE2L6,CHRM1,PLEKHB1,MS4A7,CHRM4,ZBED5,SLC22A6,NRXN2,TPP1,FADS2,CRY2,HINFP,TENM4,FEZ1,MICAL2,CTNND1,ARHGAP32,B3GAT3,C2CD2L,NTM,DLG2,CDON,USH1C,HIPK3,SIDT2,KMT5B,EIF4G2,BSCL2,RASGRP2,RTN3,SIRPB1,MRVI1,FOLH1,FOLR2,ARFGAP2,CELF1,B3GAT1,MSANTD4,DKK3,STARD10,NEU3,LYVE1,RAB30,GNG3,GRIA4,GRIK4,ADAMTS8,GRM5,GUCY1A2,HPS5,PTGDR2,HRH3,KCNA4,KCNC1,KCNJ5,KCNJ11,LMO1,LMO2,VWA5A,THYN1,DDX25,MYO7A,FXYD6,NCAM1,NELL1,NRGN,NUCB2,NUMA1,OPCML,PAX6,PC,PDE2A,PDE3B,SYTL2,PSMD13,PYGM,RAB3IL1,USP47,RDX,TRIM68,DPF2,RNH1,ALG9,ROM1,UEVLD,PRR5L,TCP11L1,LGR4,SCN2B,SOX6,ASRGL1,AMBRA1,PAAF1,SLC1A2,KDM4D,SHANK2,KBTBD4,SLN,TTC17,IGSF9B,SCN3B,ST5,PHLDB1,GANAB,FAM168A,ABCC8,ROBO3,ARHGEF12,SIK3,ZFP91,TMPRSS5,TUB,CADM1,FLRT1,BEST1,KLC2,SF1,ZBTB16,ZNF195,GDPD5,PRDM10,NAV2,SLC17A6" Coexpression 18959789-Table8 Human Viral_Zekri08_20genes GeneSigDB 3.15E-03 1.00E+00 2.32E-02 2.31E-01 6 11 "MAGI1,SLIT2,NRXN2,ITGAV,SLC1A2,MAPK8IP3" Coexpression M2246 Category D genes: p53-independent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.16E-03 1.00E+00 2.32E-02 2.31E-01 61 280 "TTYH1,KDM5D,CSMD3,HHATL,LGR5,BID,CFLAR,SCAPER,CCK,SOCS6,SLIT2,CABP1,CRMP1,SLC32A1,OSBPL3,BOC,EARS2,TMEM170A,PITPNC1,TMCC2,FAM107B,DMD,NR1D2,DNM1L,EFNA2,TMEM35A,CALCRL,EXTL2,GABRA5,GGTA1P,PRUNE2,RNF165,UBE2QL1,CFAP126,KCNMA1,AQP11,MBP,NEFM,PHKG1,CCSER2,PLCB2,SLC22A23,PTK2,ARHGEF10L,TUNAR,NCBP3,SH3BGR,KIF16B,SLC20A2,SPHKAP,SLN,RBM34,ZC3H13,FCHO1,SEPT3,FBXW11,TGFBR3,ENHO,TIAM1,LAT2,CBLN2" Coexpression M9446 Genes up-regulated in splenocytes: control versus infected with Sendai virus. MSigDB C7: Immunologic Signatures (v6.0) 3.21E-03 1.00E+00 2.32E-02 2.31E-01 38 158 "OGT,GPR146,LARGE1,B4GALT6,CLCN3,CNTN1,ABI3BP,NRG2,IPCEF1,RIPOR2,DSCAM,PRAM1,PSD2,FAM184B,GCNT2,KCNK1,NCOA7,PDE4B,MAPK10,ARID4A,RGS12,RNASEL,ATP8B4,LRRK2,KCNIP3,SAFB,RASA3,DOCK10,CCDC88A,ATF7IP,SCN3B,UHRF1BP1L,ZC3H13,COLGALT2,CLDND1,GDPD5,HPS4,DOCK8" Coexpression M1973 Genes up-regulated in primary endothelial cells (HUVEC) after knockdown of WTAP [GeneID=9589] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.21E-03 1.00E+00 2.32E-02 2.31E-01 65 302 "KIAA1211,ARRB1,MARCH3,ADAM23,ST3GAL5,KALRN,NPIPA1,FOXN3,CHN2,RAB33A,TPP1,LETMD1,C2CD2,ENTPD4,CSF1,PITPNM3,ZEB2,NR1D2,SNX29,EDNRB,ATL1,SH3YL1,ZSCAN30,FLT1,TRIM16,ATP2C1,DKK3,ERAP1,GCNT2,PCDH17,PARD3B,NR3C1,FRMD3,HNMT,ZNF678,INPP1,ZNF667-AS1,MOBP,CD200,SLC11A2,ETFRF1,SERPINE2,SSH1,ZNF655,SMOX,PMP22,SH3KBP1,PRKAB2,KIF16B,ANKRD6,SMARCE1,LIMCH1,PDZD2,BEX1,ARHGAP26,ZNF302,ZSCAN29,ANKRD12,PCDHGA4,FAM200B,HEY1,BHLHB9,VLDLR,NDRG4,PARP6" Coexpression M1422 Up-regulated genes discriminating multiple myeloma samples by the ype of immunoglobulin light chain they produce: Ig lambda (IGLL) vs Ig kappa (IGLK). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.22E-03 1.00E+00 2.32E-02 2.31E-01 14 42 "DDR1,PICK1,EDN3,TNK2,ELAVL4,FGR,MALT1,GSTM5,TLX1,NFIX,PLXNB3,SH3GL2,SLC44A1,UBE3A" Coexpression 18024791-Table2 Human Lymphoma_OrtegaPaino08_46genes GeneSigDB 3.22E-03 1.00E+00 2.32E-02 2.31E-01 14 42 "ACTN1,SLC16A4,NMT2,HOMER3,CNN3,CST3,DBN1,OPTN,CHL1,ENPP2,PRKCB,ATXN1,TIAM1,TPM2" Coexpression M6675 Genes down-regulated in bone marrow-derived macrophages at 180 min of stimulation by LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.27E-03 1.00E+00 2.32E-02 2.31E-01 37 153 "ADRA1D,NRP2,CBS,CHGA,SLIT2,CST3,PHF19,DMPK,DSCAM,OPTN,IGSF6,OLFM1,FOLR2,TUBA8,NR3C1,GUCY1A1,MAN1B1,KCNK2,STMN1,NTRK3,PBX1,SMOX,ASPDH,PCDHB17P,PTPRD,KIRREL1,RORB,RTN1,AMER2,PPP1R9A,SHC4,SLC1A3,PSD3,TIE1,TPM2,ITM2C,PLD4" Coexpression M4355 Genes up-regulated in comparison of lung tissue from wild type mice subjected to ozone for 48 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADRA1B,LTBP4,ALK,SGCE,LDLRAD4,CAST,USP2,UBE2L6,VAX2,CRY2,DCC,RUSC2,DTNA,E2F6,EDNRB,CEND1,STAMBP,SARAF,ADAM28,RAPGEF4,GUCY1A1,GUCY1B1,C5orf24,KIF5A,MARK1,SCG3,NEK1,NFE2L2,NKX2-2,FXYD1,PILRA,RAP1GAP,EXD2,WLS,YJEFN3,HSPA4L,MAGI3,SOX3,CLSTN2,ITPRID2,PJA1,TCF12,HHIP,CADM1,SEMA3B,FXR1" Coexpression M9551 Genes up-regulated in CD8 T effector cells during infection: KLRG1 high [GeneID=10219] versus KLRG1 low [GeneID=10219]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG2,TMEFF1,ADAM15,GPR146,KSR1,BTK,MTMR3,CA4,CACNA1D,CANX,SCARB1,CDH8,HECTD1,CNTN1,ELMO1,EEF1A2,ARMCX1,SPECC1,GALR1,GCNT2,KCND1,KCND2,KLC1,PAXBP1,ASPRV1,MIA2,PDE3A,ENPP2,TMOD2,PHKG1,SEMA5B,PPP3CC,RAD52,BAALC,RYR3,SOX6,SLC2A5,PDZRN3,TEX2,C3orf70,TAL1,ZFP91,TMPRSS5,ZFP37,WNK1,ST7" Coexpression M2720 Genes up-regulated in primary thyrocyte cultures in response to cAMP signaling pathway activation by thyrotropin (TSH). MSigDB C6: Oncogenic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG2,SPOP,ATP1A1,SCARB1,ZBED5,AKAP6,LETMD1,MAGED1,RCHY1,ZNF385A,CLOCK,CS,PDE4DIP,KIAA0040,EARS2,IST1,ELMO1,BSCL2,ELN,ECSIT,ACSL4,TOMM40L,STRADA,UFM1,AHCYL1,MTHFD2,LIMS1,KANSL1,CEP41,PXK,OCIAD1,MRPS18A,DGLUCY,COPZ1,KANSL3,CPEB4,TNIK,TRIM2,TMEM9,CHST5,HSPBP1,SLC35A4,TBC1D15,POLR3H,URM1,AAAS" Coexpression M5812 Genes up-regulated in comparison of untreated wild type macrophages at 4 h versus those from IRAK4 [GeneID=51135] deficient mice at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "RALGAPA1,KCTD16,DOC2A,ANXA7,ZNF583,B4GALT6,QKI,AKAP7,TBPL1,ZNF385A,CSF1,PDE4DIP,USP6NL,ARMCX2,DMD,DNAJB6,NBEA,PRUNE2,ATF7,KIF3A,ATG4C,ZNF546,IL6ST,MAT2A,NFIX,PBX1,PDGFRA,FAM98B,SSH1,SNX10,RC3H2,PTK2,USP47,FAT4,PCMTD2,NUBPL,ZFP1,RCOR3,USP33,EHBP1,GZF1,DDHD1,SYNPO2,CERS6,JMJD1C,MSRB3" Coexpression M5801 Genes down-regulated in comparison of untreated macrophages at 4 h versus those treated with LPS (TLR4 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "TKTL1,CC2D2A,ARNTL,KIF1A,ST3GAL5,OSGIN2,WASF1,CH25H,RCHY1,RBM39,CSF3R,DSCAM,DYRK1A,LRRC23,SRRM1,EFEMP1,SUCO,VTI1B,FUT9,FYB1,C15orf41,GART,GPER1,GRIK4,ATOH8,JAK2,KCNJ9,MEST,MID1,MSR1,MYO9A,PBX1,PDGFRA,PMS2,MTMR10,RALGDS,RFX5,DGLUCY,NCDN,TIAM1,MTMR14,UBC,PLEKHH2,VGF,RNF103,FRMD6" Coexpression M6580 Genes down-regulated in ITGAM+ [GeneID=3684] cells from spleens of tumor bearing mice: processed immediately versus those incubated for 24h in complete medium. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ARHGEF1,CLCN4,SLC4A7,PITPNC1,KBTBD11,USP3,RASGRP1,TNK2,CALCRL,MEX3B,HVCN1,SDCBP2,GAB1,ZNF274,ACSS1,GRK4,RAPGEF4,SPACA9,IRAK3,INPP5B,ITGA7,PDCD2,ABCB1,SLC25A23,PLTP,SEPT4,PRKACB,PTPRE,RGS4,TTLL7,RYR1,RASA3,SGK1,FAM102A,DOCK10,EPC1,MAST1,RCOR3,TTC17,CABCOCO1,KIF1B,SULF2,MGRN1,ZSCAN26,SHD,KLHDC1" Coexpression M9363 Genes up-regulated in day 7 germinal center B cells versus day 40 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "APP,SFMBT2,CA12,CAMK2B,CAMK2G,USP2,GAL3ST1,NECTIN3,LRIG1,NRSN1,YAF2,SORBS3,VPS26C,DNAJC27,RACK1,ST3GAL6,GTF2IRD2,FGF13,MEX3B,KCNMB4,PSRC1,ELOVL5,AGFG1,JAK1,MN1,NINJ2,DUSP26,VSTM2L,RGS10,RNASEL,DCUN1D2,MYH14,TMEM206,S100B,CCDC92,ATF7IP,INTS9,TBCEL,KLHL4,ARHGAP9,TIAM1,SSBP2,VLDLR,URM1,ZDHHC20,FRMD6" Coexpression M7501 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus wildtype Tfh cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "MTUS1,CC2D2A,MYOM1,NRP2,PROM1,CAMK2A,LDB2,USP2,CD38,CLU,ZNF385A,CDC42BPB,AKAP12,CTNND1,TMEM170A,DUSP9,IGSF6,F5,DLC1,FCGR3A,FGFR1,FHL1,GALC,GBX2,GHR,GPT2,WIF1,CELF5,ICA1,USP54,KHK,SCAMP5,OPHN1,RASGEF1B,DIRAS2,RAB3IL1,MEG3,SGK1,SLC4A3,PALLD,LHPP,TEK,TIE1,NPDC1,ZFP37,PIANP" Coexpression M6035 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus IL4 [GeneID=3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "METAP1D,DGKD,TNRC6C,CDK10,ARRB1,DNAH17,ZBTB10,SPAG9,EVI5L,STOML1,ZFP28,CNRIP1,ANKRD44,IPCEF1,IP6K1,SRGAP3,SLC29A4,SLC12A6,PLXNC1,FCGRT,STARD10,RBPJ,IL6R,PAXBP1,KCTD6,NUCB2,SETD4,PDE1B,PLEC,TATDN3,PPP3CA,RASGEF1B,RIPOR1,C1orf54,ARID4A,SH3BP2,AMBRA1,TCF4,AKNA,CYB561A3,ATP13A2,TK2,TNFRSF1B,RFTN2,TOM1L2,MEIS3" Coexpression M5365 Genes up-regulated in comparison of untreated mast cells versus mast cells treated with IgE at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "OSBPL8,API5,CAPN3,NFS1,KYAT1,LRBA,DCLK1,SRSF11,BAG4,SEC14L5,KIAA0513,ELMO1,DDX46,SACS,DMPK,GMPR2,ATP6V1H,GLRB,PCSK1N,ELOVL5,HSD17B1,IL6ST,MSRA,NAP1L2,SMIM7,RC3H2,POLR2F,C1orf109,TTLL7,RYR3,SEC14L1,CCDC88A,ZKSCAN3,SMARCA4,KDM4C,RBM26,SYT5,AMACR,TSC2,ZKSCAN5,CADM1,WNT7A,ZIC1,ZNF23,REEP1,CIAPIN1" Coexpression M8359 Genes down-regulated in T reg: natural versus induced cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "FAM131A,CCPG1,FAM149A,AKAP12,SIPA1L1,VCAN,CTH,KIAA0513,SPATA2,KBTBD11,DNM2,TOM1,ELAVL4,SIRPB1,F3,FLT1,GABRA5,GRIK3,NR3C1,GSN,WIF1,RBPJ,NOVA2,OLR1,FAM216A,MINDY2,PTPRE,RALGDS,RAP1GDS1,RPE65,SLA,SMARCE1,SOX10,SPTAN1,TSPYL2,NPAS3,DDN,SS18,RGL1,TAC1,TCF4,TNFRSF1B,R3HDM1,NDRG4,NUP214,FXR1" Coexpression M6090 Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL-12 (2h). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD3,GRAMD1B,OSBPL8,GAS7,ZBED1,CCPG1,ARHGEF6,CS,SIPA1L1,INTS1,FBXL5,DOCK2,FRY,EIF4G2,VPS13B,NPTN,GAA,IQGAP2,GNAS,CLASRP,PACSIN2,HMGB1,MSL1,JAK1,LMO2,MAN2A2,PTOV1,MYO5A,NAP1L1,CDK14,POLR2F,PKN2,RPL38,SCP2,CLSTN1,SPTAN1,CDK19,FCHO1,GANAB,SYNE2,DMXL2,BEST1,ZBTB16,ZSCAN26,UPF3A,MPPE1" Coexpression M8484 Genes up-regulated in B16 melanoma (day 3): untreated versus mock treatment during adoptive transfer therapy. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "TTYH1,NDRG2,PPFIA4,NT5C3B,VAT1L,ALDH7A1,NIPA1,TJP2,MYRIP,CRHBP,PDE4DIP,SRGAP3,EXOG,ELAVL4,PLEKHO1,EVL,SESN1,ITPKB,LAMP2,MYO7A,ZNF862,P2RX7,SLC25A23,CNNM2,ZNF354C,PPM1E,ARHGEF40,GKAP1,KIF21B,GLT8D1,CAND2,IQSEC2,CAMTA2,CEP68,MMS19,DNMBP,ZEB1,ITGB3BP,TP53BP1,CDK20,WBP2,FLRT1,PORCN,ZFP37,ZNF32,MAP3K12" Coexpression M5811 Genes down-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "UNC5A,AK2,SYT13,DOC2A,ANXA7,GAS7,NRP2,CD86,CLOCK,APPL1,TOMM20,E2F5,MTHFD2,RND1,TCERG1,GPD2,PSIP1,MITF,RSPO2,NFIX,OLR1,GPR85,RC3H2,PKN2,MAPK9,PSMA6,PTCH1,RFX5,ROBO1,TRA2B,MAGI3,SLC6A9,SLC12A2,EPB41L3,MPRIP,NEK4,TCF7L2,GPRIN3,ZFPM2,TJP1,TPD52L2,ELP5,VAV2,MICU3,TMEM178A,PHTF2" Coexpression M8734 Genes up-regulated in T cells: control versus IL2 [GeneID=3558] stimulation for 17h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ACADM,OSBPL1A,FAM135A,MAP4K3,APOC1,ATP2B1,C5,CBR1,CD86,REPS2,CHN2,LY86,CNRIP1,PREPL,CRHBP,OSBPL3,RHOBTB1,SNX29,FAM13A,MRO,SORBS3,EPS8,TLR7,ARMCX1,FECH,ZBED3,IQGAP2,GGTA1P,GPR34,STMN1,MEF2C,AMZ2P1,TREM2,PFKFB2,GDPD1,VPS13C,ZYG11B,REV3L,RPS6KA2,ASRGL1,PALLD,PLCB1,TAF9,WDR7,TNS1,CADM1" Coexpression M8086 Genes down-regulated in myeloid-derived suppressor cells from colon tumors: wildtype versus HDC [GeneID=3067] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "PLA2G6,ARHGAP20,DDO,ADGRB3,KIAA1549L,SNPH,SLC29A4,CALN1,NR1D2,FAM57B,ABCC9,CALCRL,EPHB1,CDHR1,CORO2B,SUCO,SRRM4,GLI2,GLRB,PTPRT,SOX21,FRMD5,GAREM2,NIM1K,C2CD4C,MAP6,MATN3,LDLRAD3,MDM4,LRP1B,FXYD6,CNTN3,GNG2,ST8SIA5,MAGEL2,DRAM2,MORC4,FNIP1,ARX,DOCK10,ZNF667,NFASC,RALYL,PRRT1,NPL,ZNF711" Coexpression M3316 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 Int thymocytes versus CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "HACE1,KIAA1324,RASL11B,SNAI3-AS1,DCAF5,CAPN3,METTL6,CDH18,TMEM59L,ABCG2,BTF3L4,SLC35F1,CTH,MAML1,RABGAP1L,ABI2,KCTD3,RCSD1,FGFR3,TACC2,MMADHC,FREM1,CBX1,MYL3,NBL1,PCBP3,SETD4,ETFRF1,TATDN3,PRKCB,TMEM104,PTHLH,TUG1,CEP97,RFX5,PRIMA1,MRAP2,RTN1,NCBP3,SATB1,MBD5,BEX1,ZC4H2,NXT2,TIAM1,SSBP2" Coexpression M9391 Genes up-regulated in follicular B lymphocytes: wildtype versus heterozygotic knockout of BCL6 [GeneID=604]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "RBM10,LGR5,MARK4,ADAM15,BAIAP3,RHBDL1,TJP2,ZFP28,ERC2,YTHDC1,RASGRP2,STX2,FAM198B,FGFR1,NEURL4,CHL1,TUBGCP4,SRCAP,TOX3,LUZP2,GRM7,IGF1,IL11RA,KCNMA1,NELL1,GPR85,PCDH18,STRN3,PRKCZ,LGI2,ROBO1,HSPA4L,WDR47,MTERF2,SOX11,EPB41L3,ARHGAP9,SIK3,TP53BP2,ZMYND8,CADM2,PRDM10,HPS4,SNX27,SLC17A6,SLC4A10" Coexpression M5711 Genes up-regulated in comparison of ActCD4TGF versus WTActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AP2A2,AMPD3,APC,ADGRB2,LARGE1,FOXN3,CLCN4,ARHGEF10,KIAA0040,DOCK4,RASSF2,PITPNC1,ZC3H11A,KBTBD11,CDON,CPEB2,USH1C,ZIC4,TAOK3,PRRC2B,FAM19A2,NIM1K,MID1,NFIA,NFIX,CCSER2,SMOX,SYTL2,ZYG11B,MCMBP,WLS,NCBP3,SLC30A10,RASA3,ITSN1,ST6GAL1,TET1,KIF1B,SEMA4A,TCF4,ATP13A2,LEFTY2,THRA,RGMB,AMOT,FRMD6" Coexpression M8632 "Genes up-regulated in bone marrow-derived dendritic cells treated with 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose." MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ARID1A,ABCD2,APC,GPR146,CAMK2G,CAST,RCBTB2,ANKRD44,AATK,IPCEF1,GALNT9,KIAA0513,TMCC2,KAT8,FOXO3,SESN1,CACFD1,ATG4C,HPS5,KIF5A,STXBP5,L1CAM,GPR155,MAN2A2,TM6SF1,MEF2C,RTL5,RETREG1,PURG,MINDY2,RNASEL,TMLHE,PCMTD2,ITSN1,ST6GAL1,SLC8A1,TET1,SRPK2,CAMSAP2,TCF12,ARHGAP9,THRA,TLR4,R3HDM1,ZNF708,ADAMTS10" Coexpression M3164 Genes up-regulated in comparison of Th2 cells versus Th17 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "C6orf89,LCORL,GPAM,ARHGAP5,CACNA1A,AKAP7,CSF1,PLCXD3,SLC45A1,ZFYVE16,ZBTB24,CCDC3,FAM57B,MTSS1L,SLC9B2,MEX3B,CAB39,GPR75,GNAS,ADGRA3,GPM6B,GPR22,ATOH8,IGSF1,ASPRV1,SRSF12,SCAMP5,ADAM22,MYO9A,ZNF862,PDPK1,SLC36A4,PRPSAP2,SUGCT,ZFP2,TMCC1,NMNAT2,SAMSN1,KANK1,ASTN2,C9orf85,PPP1R3F,C12orf4,RTN4,ADAMTSL3,SOCS4" Coexpression M7289 Genes down-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "RNF157,ZNF608,ARNTL,BCL7A,CFLAR,MTMR2,MAP7,AKAP12,ARMCX4,PLEKHM1,DMPK,TSPAN5,EGR3,LPAR6,SRPK3,PLEKHO1,EPB41L2,PTK2B,ATP8A1,TESK2,FGF13,SARAF,DBF4,DCLK2,RAPGEF4,BACH2,IL12A,INPP1,LDLRAD3,MX1,PBX1,PDE2A,PSAT1,RASGEF1B,SPDL1,RBBP8,EMID1,LRRK2,SATB1,BEX1,BHLHB9,TRPS1,SSBP2,UBE2H,SLC30A4,CERS6" Coexpression M6408 Genes down-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (12h). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "KIDINS220,ARNTL,ARRB2,ATP6V1G2,DDR1,CAST,CD86,CCPG1,MAP4K4,ZFP28,CLOCK,RBM39,AKAP12,CSNK1E,ATRNL1,HP1BP3,HIPK3,EPB41L2,CDKL3,SARAF,GABBR1,SPIN1,MAP4K5,LRRCC1,TUBB2B,VWA5A,MOG,SESN3,POU6F1,WBP1L,RAD52,PRR5L,STK32B,ATAT1,SEMA6D,MAGI3,ATF7IP,DBNDD2,ERBIN,FCHO1,TBCEL,VAV1,LAT2,CLDND1,C12orf4,FRMD6" Coexpression M6606 Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL6 [GeneID=3569] and LPS (45 min). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "LCORL,PDXK,BACH1,C1QC,CANX,CD86,CDC25B,RCBTB2,ARHGAP22,MAGED1,ENTPD4,OSBPL3,PHF14,KIAA0513,FRY,RASA4,VPS26C,PTK2B,SESN1,KCNJ10,KHK,STMN1,LMO2,RTL5,NFIA,PIK3C2A,PRIMPOL,TUG1,PBRM1,AMBRA1,SLC11A1,SLC12A2,ABTB1,GLT8D1,CLASP2,SAMSN1,EPB41L3,TAL1,TBCEL,DMXL2,ZFP90,AKNA,MTMR14,TRPS1,HPS4,FXR1" Coexpression M4478 Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "LTBP4,BIN1,ZSCAN18,LRBA,CDC25B,PLEKHB1,RAB33A,MAGED1,LRIG1,FAM169A,GPRASP1,SPOCK2,ENO2,SH3YL1,EVL,ZMYND11,SESN1,ZNF276,BACH2,NELL2,NUCB2,CCSER2,RETREG1,LRRN3,PKIA,PRKCZ,SIDT1,CCDC25,SATB1,FAM102A,KBTBD4,TNIK,KIF21B,KDM3A,MPRIP,CEP68,SYNE2,DNAJC9,PJA1,DDHD2,DOCK9,AKTIP,KAT6B,TPD52,ATP6V0E2,SLC38A1" Coexpression M3151 Genes up-regulated in comparison of T follicular helper (Tfh) cells versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG3,MAP4K3,ATP2B1,DPY19L3,CAST,CCNT1,AKAP5,RBM39,CRMP1,OSBPL3,SPATA2,USP3,ABI1,ASB3,STRADA,SEC24B,USP21,NEURL4,RAPGEF6,DCLK2,GNG4,MBD1,CHIC1,MEST,NFIA,CNOT4,RC3H2,MAPK8,PTPRO,CEP97,ARID4A,RFX3,CCDC82,CARF,PEAR1,SCAF8,ST8SIA1,PEX26,SMTN,WDTC1,AGTPBP1,AP4E1,ZNF384,SF1,ZSCAN26,EMSY" Coexpression M5207 Genes up-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ASIC1,ADCY8,GRAMD1B,APOC2,ASTN1,CACNA1B,CACNA1E,CACNG1,USP6,CLIP3,ATRNL1,SLITRK5,DRP2,EFS,CDHR1,CACNG3,FOXG1,MSTN,GFAP,HPGDS,DBF4,GLRB,GPM6B,GRM8,GPR45,SMAP1,KCNB1,KCNJ9,KIF5A,KTN1,MEIS2,MN1,SERPINI1,TNPO2,MAPK12,NLGN4Y,EPN2,SOX1,NACAD,ANKRD28,TCF7L2,WASHC4,LEFTY2,TPM4,UBE2H,SCG2" Coexpression M3369 Genes down-regulated in comparison of Th2 cells versus natural regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AP2A1,OSBPL8,ZFAT,TNRC6C,PDXK,BAIAP3,FMNL3,CBFA2T2,DCLK1,B4GALT6,ARMCX2,COPS7A,CDON,TSPAN5,RBM12,PAN3,RCSD1,DCTN2,WASHC2A,KIAA1958,GRIA2,CLASRP,KCNC2,MKLN1,SESN3,OPA1,PURG,SEPT4,MBOAT7,PPP2R2B,GRAMD1C,DEF8,FAM120C,ZSCAN2,ROGDI,BSDC1,C12orf49,ATXN7,SCN2A,HES6,DHX30,SMARCA4,MYCBP2,CAMSAP2,ATMIN,JPH3" Coexpression M3599 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADCY6,BRAP,ADORA1,ADRB2,AP1B1,MAP4K3,SEC11C,BTRC,CAMK2B,USP2,CLTB,ABCG1,SDC3,IP6K1,NR1D2,ABCC5,EEF1A2,ING4,STX2,ERCC2,TBR1,GABBR1,INPP5K,GP1BB,RAPGEF4,GRIK1,IL6R,INSM1,MAP4,MOV10,NTRK3,PDE4B,PDE1B,SPATA6,RETREG2,RAB5B,BSDC1,ZYG11B,RFX2,RGS3,GALNT10,SCAF8,SCMH1,ST5,MAPK8IP3,TCF7" Coexpression M4094 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG2,ADORA1,HACE1,ST3GAL5,CACNA1D,CBLN1,METTL6,SEPT7,NOG,ABCG2,FHL5,CNN3,TBPL1,ECE2,BLOC1S6,G3BP2,PDCD6IP,DYRK1A,EDNRA,PHC2,EBI3,SRPK3,SLC37A3,TNRC6A,LNX1,DIDO1,NR3C1,IRF8,INSM1,VWA5A,KITLG,NDP,SH3KBP1,PTPRE,RALGDS,MCMBP,PEX26,GKAP1,TAB2,RGL1,TAL1,FBXW11,TBL1X,SYNPO2,RTN4,ZDHHC20" Coexpression M5484 Genes up-regulated in comparison of dendritic cells (DC) versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ASPHD1,ALCAM,ARNTL,ASPH,BID,SCARB1,SOCS6,ARHGAP22,EPS15L1,TPP1,ABCG2,CREB5,CST3,SEC14L5,PLEKHM1,ARMCX1,FAM198B,CHST15,SEC23B,ATP6V1H,SESN1,GPD1,LILRA2,GPER1,GYG1,LMO2,MATK,MITF,SCG3,PCSK5,PILRA,FA2H,PTK2,PTX3,MRAS,WDR37,TMCC1,SST,MTCL1,ROBO3,TAL1,AHCYL2,TNS1,TRIO,FAM13C,NLRP3" Coexpression M5498 Genes down-regulated in comparison of macrophages versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADAR,SPOP,BACH1,CACNA1E,SLC25A14,REPS2,CDH2,ADGRG1,RAB33A,CRYBB1,IPCEF1,PPP1R16B,CX3CR1,FBXL5,SMG7,FRY,ELAVL3,EIF1,TUBD1,CDHR1,EXTL1,PRKAG2,GAB1,ZNF44,CNTRL,HRH3,HSPA1L,NACA,ODF2,ING3,SAMD9,TUG1,RFX5,ZDHHC4,NCBP3,SMPD3,CDK5RAP3,KIF21B,PLCB1,AGTPBP1,DICER1,TLL2,ZNF177,GDPD5,MARCH8,PHTF2" Coexpression M9405 Genes up-regulated in peripheral blood monocytes (PBMC): healthy donors versus patients with HCV infection. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ABAT,GPR158,CC2D2A,CDC14B,PTCH2,CCNT1,RAB3C,TPP1,FAM171B,TOMM20,EGFR,FGF13,NSG2,CPLX2,DIPK1A,KCNC2,GPR155,MAT2A,NINJ2,PURG,POU6F1,MAPK8,TTC13,ROGDI,NUDT11,LRRK2,ZNF354C,RASA3,EPN2,SLC22A4,MAST1,INTS9,SNCA,LMBRD1,ZC4H2,PLCB1,TPCN2,RALYL,C18orf54,HEY1,TSN,TUBB2A,SLAIN1,ZNF23,ZFP41,IFT88" Coexpression M3705 Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with poly(I:C) (TLR3 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "PLA2G6,PARG,KCNAB2,ALS2,CAMK2G,CCKBR,CHRNB2,HECTD1,LETMD1,FEZ2,KIAA0513,BLOC1S6,CPEB2,ATN1,ANKRD46,GOLGA7,MRPL37,F5,FCGR1A,NSG1,FAM120B,NEK6,GLUL,GRIK5,HNRNPK,HTR5A,JAK1,ARHGAP12,LRP1B,SMIM11A,NUCB2,ANLN,RETREG2,ELOVL2,NKAIN1,CASC3,KIF21A,FAM102A,KIF13A,ERC1,BEX1,CNTN2,ACSL6,ITGB3BP,HRASLS,IFT88" Coexpression M3213 Genes up-regulated in comparison of mature NK cells versus intermediate mature KN cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ELFN2,PLEKHH1,APOC2,ATP1A3,NOL4,TTC9B,DLGAP1,SULT4A1,FHL5,TCAF1,DPH1,PLXNC1,RCSD1,PPP1R1B,FGR,TACC2,SARAF,IP6K3,TUBA8,INSM2,MFSD2A,OPALIN,NIM1K,INPP5B,KIT,MAOB,MDFI,DDX25,MYH7,NAP1L2,PENK,RETREG1,PACSIN1,SH3KBP1,RAB3A,BEND5,KHDRBS2,TMEM200C,KDM4D,RADIL,MCF2L,VWC2,PPIL6,SLC38A1,FAM47E,PAK5" Coexpression M9886 Genes up-regulated in CD4 [GeneID=920] T cells: unstimulated versus activated. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG2,ADD3,ANK3,LGR5,N4BP2L1,CACNA1I,CACNA1G,DDR1,PDE4DIP,GPRASP1,C2CD2L,AK5,KBTBD11,FAM13A,GPHN,EPS8,F5,GABBR1,TRAF3IP2,ICA1,IL6R,IL6ST,KCNH2,KCNN1,MSRA,NUMA1,OCRL,PLCL1,PTK2,BSDC1,GAL3ST4,MORC4,SELL,FAM102A,HKDC1,LIMS2,RAB3GAP1,SORCS3,ZC4H2,MCF2L,OBSL1,TIAM1,TPM1,SSBP2,WNT7A,NETO2" Coexpression M5674 Genes down-regulated in comparison of TconvLN versus TregLN (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ATP2A2,DPY19L3,MTMR3,MTMR7,CD86,CD38,CD81,ZBED5,SLC4A7,CNRIP1,LRIG1,OSBPL3,SOCS5,HDAC9,DMD,ABI2,PLXNC1,DENND4A,SLC9B2,SDCBP2,NCKAP1,SESN1,ADAP1,STON1,ADAMTS6,SMAP1,IRF8,MATN2,PPM1L,ABCB1,WLS,RXRA,SH3BP2,TRIM67,SLC12A2,KIF13A,SAMSN1,SEPT8,C3orf70,AHCYL2,DNAH7,TNFRSF1B,VAV2,ITM2C,PHTF2,FRMD6" Coexpression M8027 Genes down-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "MAP4K3,ARHGAP5,BCL2L2,WASF1,ZMYM4,RCBTB2,SOCS6,B4GALT6,NDST3,CLIP3,CTNND1,RIMS3,ARMCX2,ELMO1,E2F6,LPAR6,F8,ARMCX1,FKTN,TRAF3IP2,GATM,HPGDS,ADGRA3,PRUNE2,GUCY1B1,LIMS1,OPA1,SNX10,FTO,SCHIP1,PTPRD,C1orf54,NUDT11,RPE65,AP1AR,SCN3A,SELL,CCDC92,ZNF667,RAP1GAP2,SAMSN1,KANK1,FAM168A,TST,DNAJC12,ZNF189" Coexpression M9548 Genes down-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: wildtype versus ID2 and BCL2L11 [GeneID=3398;10018] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ARNTL,RGS20,CAPRIN2,SYNJ2,CRYM,RGS6,ZFYVE16,DSCAM,PHF20L1,PLXNC1,NSG2,GAD2,TUBGCP4,GFRA1,GP1BB,MUM1,MSL1,MYLK2,KCNN2,STMN1,SMAD1,MID1,MPP2,SESN3,MSRA,TAGLN3,PCBP3,NRCAM,PBX1,ELOVL2,PEX2,RGS7,DGLUCY,SEMA6D,GALNT10,MYO18A,SLC8A3,SLC11A1,SLC15A2,SEMA4A,TCF7,FRYL,ITGB3BP,ACTR6,ZBTB14,ZIC2" Coexpression M9591 Genes up-regulated in thymic T conv: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "SERPINA3,ABR,NDRG3,NDRG2,ALCAM,MYH7B,RGS11,ARHGEF2,SOCS6,ZBED5,PLAA,SDC3,KIAA0513,RASSF2,MBNL2,C3orf18,ENO2,DLC1,FER,STARD3,GRB10,KLC1,MGAT3,NKX2-2,SMOX,MAGEL2,RAP1GAP,RNASEL,RPRD1A,GALNT10,MRAS,SGK1,SLC6A9,PALLD,CDK19,SYPL1,ANKRD28,TAF6,WWC1,SYNE1,AKTIP,NACC2,TJP1,TSN,TST,ZFAND5" Coexpression M5701 Genes down-regulated in comparsion of sfActCD4 versus ActCD4 (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "TMCC3,APC,DGKZ,APP,RASL11B,ATP2B1,NIPA1,CAMK2D,KCNAB3,AKAP12,CTNND2,USP6NL,TOX,CDON,FRY,MRVI1,ATP8A1,FGF13,AGAP2,AKAP3,PDLIM5,TMEM8B,GRK4,ADAMTS6,CHST6,PPM1L,NFIX,OGDH,CDIP1,MED1,RFX3,RPS6KA2,SELL,CASC3,SLC14A1,KLHL7,ZC3H4,CAMTA1,DNMBP,TBL1X,KIAA0930,TCF7,SLC44A1,TPD52L2,SLC30A4,WIPF2" Coexpression M7516 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus non-Tfh cells with SH2D1A [GeneID=4068] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD1,ADD2,WDR35,ANK1,EPB41L5,GPAM,PLA2G4C,BLM,NFS1,KYAT1,TBRG4,BAG4,GAPVD1,ALKBH8,RCAN1,OPTN,SH3GLB1,PLXNC1,TNK2,EPB41,STX2,SCML2,FECH,STARD10,DHRS4,CECR2,GRB10,IBA57,GPR155,MIA2,COMMD5,MTR,SAMD14,PPP3CB,CEP41,EPDR1,GDPD1,PEX5,SH3TC2,ZDHHC14,SLC12A4,HIF3A,ZMAT3,BEX4,BCL2L13,NUP214" Coexpression M9196 Genes up-regulated in T reg: NRP1+ [GeneID=8829] versus NRP1- [GeneID=8829]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ASPHD1,DOC2A,AMPD3,MARCH3,CAMK2B,TJP2,CSF1,RGS6,CSF3R,HDAC9,ARRDC4,KATNAL1,FECH,GABRA3,TRAF3IP2,AHCYL1,STARD10,GPM6B,FAM222A,IL6R,ITGA7,JAK1,NCAM1,NUCB2,P2RX7,TREM2,PDE2A,PTPN13,RGS3,KCTD17,RNH1,BAALC,RXRA,SH3GL2,SLC12A2,ZNF423,TSPYL2,NFASC,ST5,STAC2,SYT11,FGD4,WWC1,TIAM1,SYNPO2,OSBP2" Coexpression M6440 Genes up-regulated in CD8A [GeneID=925] T cells versus B1 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ACLY,TMCC3,FAM135A,PHYHD1,API5,MTMR9,FEZ2,SOCS5,ECE2,RIMS3,DAPK1,KBTBD11,RCAN1,SLC43A2,SIRPB1,FCGRT,POLK,UBE2E3,FYN,GAB1,GATM,GCNT2,RASSF8,NCKAP1L,ELOVL5,IL6ST,JAK2,MATK,LRP12,PLEKHB2,C1orf54,RNH1,ALG9,TRIM46,MRAS,SIRT2,ITPRID2,EPB41L3,RGL1,DIP2A,NSFL1C,EHBP1,TF,ZMAT3,RNF103,ITM2C" Coexpression M5481 Genes up-regulated in comparison of dendritic cells (DC) versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ABHD6,ALCAM,GAS7,ARRB1,BCL2L2,C5,CAPN3,SCARB1,SOCS6,TPP1,IFFO1,CDC42BPB,ZNF804A,SV2B,TRAPPC9,SIDT2,PCOLCE2,EPB41L1,IGSF6,FGR,FLT1,SYT17,GBX2,MSTN,SESN1,LILRA2,LINC00667,CNOT4,TREM2,SMIM7,PILRA,PTK2,ZSCAN32,TTC13,C1orf54,MRAS,ARHGEF40,SLC22A4,LMBRD1,SRPK2,ROBO3,TAL1,NPL,TTC3,CSDE1,MVB12B" Coexpression M8847 Genes down-regulated in multipotent progenitors versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG3,CDC7,AGT,C6orf89,APOC2,BCL2L2,C5,CA8,CDH2,CS,IP6K1,B3GAT3,HP1BP3,MED24,WDR20,FAM107B,CPEB2,ANKRD46,TNK2,BSCL2,MTSS1L,F8,AMOTL2,ATP2C1,SEPT9,GJB1,ZNF276,CRCP,TNRC6A,NR3C1,IGF1,IL11RA,PMP22,RETREG2,DEF8,PTPRB,REV3L,RXRA,ATXN2,SMARCE1,SYT1,UBC,UBE2H,ZNF32,EVI5,SCG2" Coexpression M6447 Genes up-regulated in CD8A CD8B [GeneID=925;926] versus B1 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "OGT,TNRC6C,MIER1,CDK13,MARCH3,STX16,DOCK11,SYNJ1,CCPG1,CNOT8,C4orf33,SLC25A27,RCHY1,TBPL1,KIAA0513,TIAM2,KBTBD11,VPS13B,FGR,MPP6,GAD1,RAPGEF6,ZNF274,GCNT2,GFRA2,ZNF638,DIDO1,MIER3,BLOC1S2,MYO9A,ABCB1,PURG,PPM1B,PTPRE,CLIP1,DOCK10,DOP1A,ZBTB43,RAP1GAP2,ANKRD12,KIAA0930,AKNA,NR2C2,MFF,DPF3,RNF146" Coexpression M6001 Genes up-regulated in macrophages with SOCS3 [GeneID=9021]: untreated versus IL6 [GeneID=3569] for 400min. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ABHD6,TMCC3,ALDH4A1,BCL2L2,CFLAR,NAE1,SPAG9,AKAP7,FAM149A,CHD1L,EARS2,USP3,ING4,EXTL2,EZH1,ST3GAL6,PSD2,NSG2,AP4B1,ACSS1,STARD10,AHDC1,COQ10A,METTL21A,KHK,SFXN5,LDLRAD3,MEST,ZNF862,NCF2,ALDH1L2,PCBP3,PFKFB4,PTPRE,CEP97,RAD52,RGS3,TMEM100,CLSTN1,SPART,ANKRD12,PDLIM2,AKNA,MICAL1,PLD4,ADAMTS10" Coexpression M5323 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 72 h versus those from old donors treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADARB2,PPP4R4,IL33,CA8,CACNB2,CALB1,MYOM2,DGCR9,FEZ1,VCAN,DCAF4,MFAP3L,NR1D2,OPTN,LINC00599,EPB41,COQ7,MSTN,GFRA1,PRUNE2,GPR12,GRIA1,GRM3,FICD,ITIH2,MYL3,NEFH,NPTX2,PCBP3,TMOD2,ABCB1,PMP2,SPATA6,MAPK8,LAMA1,PTPRH,RAD51D,KHDRBS2,ARHGEF10L,ZNF532,C12orf49,PEX26,HECW1,ZC3H4,TPM4,LMAN2L" Coexpression M9685 Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 60h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ACTN2,ADCY6,C1QTNF1,MAP4K3,ARNTL,NUMB,CA12,P2RX6,CLGN,CHRM1,C2CD2,CSF1,GSDME,FAM107B,RCAN1,DNAJB6,PIPOX,AMOTL2,SPECC1,NSG1,SARAF,ACSS1,GLDC,GLUL,STMN2,IPO5,LIFR,NF1,SCHIP1,PPP3CB,PRKACB,PTPRE,MRPS18A,CASC3,CCDC88A,MYT1L,SSPO,NEK4,SYP,SYT1,RBFOX2,WRN,ZBTB14,NDRG4,RNF103,FRMD6" Coexpression M5705 Genes down-regulated in comparsion of sfActCD4TGF versus ActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "SNX30,MTUS1,CARNS1,DGKD,MTMR3,CAST,MAP4K4,LRIG1,ARHGEF10,IPCEF1,ARHGEF4,DOCK4,RIPOR2,MAML1,PITPNC1,RABGAP1L,CDON,USH1C,KMT5B,CALCRL,GPHN,SLC43A2,TBC1D16,FGF13,ACSS1,TUBGCP4,SESN1,PRRC2B,ADAMTS6,IL6ST,MBP,NFIX,NTRK3,NUCB2,SMOX,CEP97,SELL,CHD9,UNC80,RAP1GAP2,TCF4,KIAA0930,SLC44A1,PDIA2,IFT88,SENP7" Coexpression M7193 Genes down-regulated in transitional B lymphocytes from cord blood: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD1,ADD3,BCAR3,PITPNM2,GPAM,ARNTL,NAE1,CAMK2D,MAP7,STOML1,RTTN,GUCD1,ASB3,TNK2,RCSD1,TLR7,EZH1,EFCAB2,ZNF512,GSTT2,HES5,JAK1,KTN1,CD200,MYO7A,RETREG1,EXOSC10,PMS2,SH3KBP1,MINDY2,PRKCB,SIDT1,CEP97,PCMTD2,MTERF2,CLUAP1,SPTAN1,TCF12,SZT2,TK2,C9orf85,UBTF,SLAIN1,POLR3H,SH3GLB2,ACTR3B" Coexpression M6548 Genes down-regulated in activated macrophages: classically (M1) versus alternative (M2). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AGT,RGS20,CADM3,TTLL9,CFAP410,ENTPD6,PCYT1B,CALY,DCT,NTM,DLG4,PRAM1,FCGRT,AKAP3,B4GALNT1,TXNL4A,GPR37,GRIN1,NXPH3,LIX1,IL12A,KCNJ5,KIT,MATN2,CCDC80,PDE4A,GDAP1L1,SDK2,TNPO2,POU3F2,DIRAS2,PTPRN,PEX5,RAD51D,VEPH1,AMER2,KIF21A,PEG10,SMOC1,VAMP1,MCF2L,TNS2,HIF3A,TUB,KLC2,KCNK12" Coexpression M9434 Genes down-regulated in comparison between in vivo derived natural T reg (nTreg) and converted ex-iTreg (induced T reg that lost FOXP3 [GeneID=50943] expression). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "PDZD4,KIF6,PKP4,DACT3,CARMIL3,CDH18,SULT4A1,RAB26,PCYT1B,NRSN1,PHYHIP,SPOCK3,TACC2,NSG1,STAU2,MEGF10,GABRA2,WASF3,RAB30,PCSK1N,PTPN5,ZBTB49,IGFBPL1,PDE3A,MTRF1L,NKAIN4,DIRAS2,PTN,PTPN13,MORC4,RLBP1,PRR5L,RYR3,RUFY2,SLC6A1,TET1,KDM3A,ZNF423,BEX1,NACAD,NECAB1,HEPACAM,BEST1,TMEM178A,SCG2,SLC17A7" Coexpression M9659 Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 10h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "SYS1,FZD9,SPOP,APOC2,RASL11B,MTMR9,SYNJ2,CALB2,CHRNB2,CLU,TIAM2,SNAP91,WDR20,EPB41L2,PIPOX,RACK1,FDFT1,FHL1,SGIP1,NELFCD,GATM,GDF9,GLDC,IRF8,IGFBP1,RSPO2,MX1,SFR1,PCMT1,PGAM2,SERPINE2,RETREG1,EPB41L4B,UHRF1BP1,PTHLH,RNASE1,KDM3A,PEG10,TCF7,LRRC8A,RBFOX2,NPL,C9orf85,TSC2,UGT8,FIP1L1" Coexpression M5033 Genes down-regulated in comparison of SP2 thymocytes versus SP3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "OSBPL1A,SYT13,ANK3,ARMC12,PHYHD1,LRRC4C,BAIAP3,CAMK2A,NFS1,ZNF385A,HDAC4,KIAA0586,ABCC5,CERCAM,ARPP21,B4GALNT4,LPAR4,GRIA1,KHK,MIA2,NTRK3,GLIPR1L2,PALM,CDK14,SERPINI1,SEPT4,PRODH,SIDT1,PTPRG,RIPOR1,CEP97,FAM184A,ATP8B4,EMID1,ST6GALNAC6,SELL,SGK1,ACSBG1,TMEM151B,PRRT1,MGAT5B,TRIM9,ZBTB16,POLR3H,AMZ1,TMEM163" Coexpression M6381 Genes up-regulated in naïve B lymphocytes versus plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "SNX32,APP,ATP1A2,STX16,CAMK2G,FMNL3,CBFA2T2,DNAJB5,TMEM184B,MAP4K4,OSBPL3,SDC3,ZBTB24,ABI1,PHF20L1,C8orf37,EPB41L2,EZH1,TUBB3,SEPT9,PRRC2B,CNDP1,GPD1,STON1,CACFD1,COQ10A,IL1RAPL1,MAP4K5,HMGCL,PPM1L,RETREG1,PRR5L,SEMA6D,MAGI3,ABTB1,RCOR3,ERC1,SS18,STAC2,STX1A,PJA1,ZFP90,USP22,AKTIP,SMUG1,SLC17A7" Coexpression M4033 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "TXNDC16,SPOP,MRTFA,ARHGAP5,CHRD,NUMB,CARS,MYL6B,GDA,DSCAM,EZH1,WAC,FCGR3A,SEC24B,SPSB4,TPK1,NSG2,GAD2,AHCYL1,INPP5K,TNRC6A,LNX1,CLASRP,PSIP1,L1CAM,MATK,IDNK,TREM2,PFKFB3,SMOX,POU3F2,SPDL1,SCN3A,EPC1,SON,DBNDD2,ITPRID2,RGL1,TCF7L2,FRYL,UBE2H,WIPF1,ZBTB16,ZSCAN26,PMEPA1,KAT6A" Coexpression M3488 Genes down-regulated in naive CD4 [GeneID=920] T cells from adult blood versus thymic stromal cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "TMEFF1,ATP1B3,BCHE,BID,GYG2,MYRF,SLC25A14,CARS,CBS,LDB2,SLIT2,KIAA1549L,HOMER3,CNN3,COL4A5,NECTIN3,CTNND1,EDNRA,SIDT2,CHST15,ATP2C1,GLRB,NUDT21,RAPGEF4,GSTT2,HAS2,NEFM,PCDH9,LRP12,ERI2,TMEM100,BAALC,SEC14L1,HSPA4L,SCG5,BTBD3,ZCCHC24,DOK5,SS18,KAZN,CAMSAP2,PDLIM2,FBXW11,DMXL2,NAV2,PLSCR4" Coexpression M7976 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADAR,TMCC3,AGT,PLA2G6,SHROOM2,SFMBT2,CA12,CACNB2,CAST,ZFYVE9,COL9A1,FBXL5,KBTBD11,DLG3,TSPAN5,PAN3,CORO2B,PPP1R1B,PRELID3A,MALT1,GLRB,GLS,KAT7,ELOVL5,SHISA6,C5orf24,RBPJ,VWA5A,CHIC1,MIR4697HG,MYO5A,SFR1,NLGN3,PRKCB,VPS13C,SETD5,ATXN1,ATXN7,BCAN,SOX3,RAP1GAP2,JMJD6,ARHGEF9,TRPS1,TUBB1,SOCS4" Coexpression M9846 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "CPNE2,PKP4,ATP6V0A1,TTC9B,SYNJ1,CACNB2,CD86,CD38,CLTC,CSF1,SIPA1L1,SDC3,ARMCX2,RPS6KL1,EDNRB,OPTN,TUBGCP4,KIAA1958,CIT,SLC2A6,AGFG1,INPP5B,JAK2,LAMP2,VWA5A,MAT2A,MGAT3,OGDH,ABCB1,C19orf57,POU6F1,RASGEF1B,SOX6,IFT122,MBD5,ZCCHC24,MYCBP2,AHCYL2,MTMR14,TP53BP2,ELFN1,ZNF213,CERS6,ADAMTSL3,MSRB3,SLC39A12" Coexpression M8567 Genes up-regulated in Th1 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD1,ADD3,ALCAM,AMPD3,TNRC6C,NCOA1,GPR146,CDC25B,CSF2RA,ATRNL1,SOCS5,PDE4DIP,MYADM,PITPNC1,GUCD1,KBTBD11,FRY,CACNG7,RTN3,TESK2,PRKAG2,KLF12,DIPK1A,L1CAM,MAN2A2,CD200,SLC36A4,PRKCB,RAB3A,CEP97,ERI2,GTDC1,ZNF354C,MAPK12,ATXN2,PEAR1,PSD3,ZMAT3,THRA,UBE2H,MICAL1,TUBA1A,ZDHHC20,SNX14,SSPN,KLHDC1" Coexpression M4484 Genes down-regulated in comparison of naive B cells versus unstimulated dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ABR,ABHD6,DGKZ,ARRB2,BID,SYNJ1,AIFM1,RCBTB2,RNF14,NCOR2,FEZ2,DOCK4,SIRPA,DNAJB6,DNM1L,EIF4G1,RTN3,FCGRT,SEC23B,SMC2,TPK1,GAA,MTHFD2,GLS,ADAP1,GSN,ITGAM,LAMP2,TM6SF1,MITF,NRGN,TREM2,ZFYVE21,LRP12,PILRA,PLEKHB2,ROGDI,ATXN1,CCDC88A,SAMSN1,EPB41L3,ZNF106,TIAM1,TPM4,TST,RTN4" Coexpression M3251 Genes up-regulated in comparison of Ig isotype switched memory B cells versus plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "NDRG3,PPFIA1,APP,CDK13,CAPRIN2,ZSCAN18,NCOA1,ATP2B1,BTK,PTBP2,SYNGR3,SMARCAL1,USP6NL,CYBB,ARHGAP24,ZFYVE16,MAML1,GIT2,PLEKHO1,PTK2B,ATP8A1,TRAF3IP2,RAPGEF6,SEPT9,BTN2A1,INPP5B,MTR,PIK3R1,SNX10,PTK2,ZSCAN32,RNF220,SLC25A36,FAM192A,PEX26,WDR47,BTBD7,KDM3A,CEP68,ZMAT3,TP53BP2,ZMYND8,LAT2,ZBTB14,ATP6V0E2,FIP1L1" Coexpression M4129 Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "HACE1,AMPD3,PKP4,TMEFF1,CH25H,CHM,MS4A7,CP,CX3CR1,MAML1,DNAJB6,EBI3,GOLGA7,PTK2B,FCGR3A,CAMSAP1,FYB1,MTHFD2,RAPGEF1,GSTM5,IL12A,JAK2,LAMP2,CD200,NPY,PC,ENPP2,PENK,SNX10,NLE1,SCHIP1,UHRF1BP1,RAD17,LRRK2,SEC14L1,SLA,SLC1A2,SLC11A1,TBCEL,SYNE1,PSD3,TJP1,ANKRD24,BCL2L13,SLC13A3,CSDE1" Coexpression M3864 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "C1QTNF4,NCOA1,KALRN,KCNAB3,GPR37L1,CHRNB2,ABCG2,HINFP,VCAN,FBXO25,STARD3NL,KCNMB2,CHST15,KIAA1109,BAIAP2,PHYHIPL,ALDH1L1,GFRA2,GRM8,HPCA,IL12A,PAXBP1,PIK3AP1,DBNL,NUCB1,TREM2,USP47,CLIP1,FOXRED1,SGK1,SH3BP2,FAM102A,CCDC92,KBTBD4,RGL1,ARL10,TPM2,PDSS1,SGK3,PLPPR2,TFIP11,ZFAND5,TMEM163,CAB39L,FXR1,DPF3" Coexpression M7361 Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ELFN2,ADCY5,KIDINS220,PITPNM2,TNRC6C,ARRB1,CCPG1,SLC32A1,FEZ2,ATRNL1,IPCEF1,HP1BP3,GUCD1,RHOBTB1,ATN1,TSPAN5,VPS13B,EPHA5,STAG2,GAA,L1CAM,LMO2,MATK,MEF2C,MTR,P2RY13,NFYA,PENK,PIK3CD,MAPKAP1,GRAMD1C,RIPOR1,USP47,TRIM68,MCMBP,DHX30,ATF7IP,CXXC4,GKAP1,SLC37A2,KIAA1107,DAAM2,LRTM2,VAV2,PORCN,ST8SIA2" Coexpression M6603 Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (45 min). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "METAP1D,SNX32,CH25H,SCARB1,COX4I1,SLC35F1,SIPA1L1,TOMM20,DNM1L,E2F5,ASB3,EIF4G2,SPEG,ACSL4,SLC9B2,UBE2E3,ADGRA1,MEGF10,GABBR1,GABRA3,B4GALNT1,GCNT2,GK,GRIA2,HNRNPK,HTR5A,OLFM3,SFXN5,MAOB,CHST6,MID1,NAP1L1,GPR88,CHAMP1,OGDH,MAPK8,MAPK10,RBBP8,RGS12,STX1A,FRYL,TNS1,UCHL1,CCDC136,PLPP4,HNRNPA3" Coexpression M3982 Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "METAP1D,TBC1D14,ALAD,MRTFA,ARHGDIG,MARK4,AIFM1,LRBA,NCOR1,CS,UBXN2A,MAML1,CD99L2,BSCL2,TESK2,GPR19,PTPN5,ACOT7,FAAP20,LSS,GIT1,ETFRF1,PENK,PSD,UHRF1BP1,RAD17,RASGRF1,ZFHX4,RTN1,SATB1,ATXN2,ST8SIA1,SLA,WDTC1,THSD1,NCDN,RHBDL3,CLASP1,TEX15,AKTIP,PARD3,METTL3,TSC1,PCDH20,SPHK2,TFIP11" Coexpression M7986 Genes up-regulated in macrophages (12h): rosiglitazone [PubChem=77999] and IL4 [GeneID=3565] versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADCY2,ARNTL,NOL4,BMP7,CH25H,USP2,INA,ENTPD2,COL9A3,IGDCC3,CRMP1,ABCG1,GSDME,GUCD1,REEP2,MED12L,AFF2,SPECC1,GABRG2,MAP7D2,ADAMTS6,PTGDR2,KCND1,KCNN1,NAP1L3,NOVA2,NTRK3,PDE3A,PTPRB,SGSM1,RXRG,ABLIM3,SLC1A2,ZNF423,STAC2,AZIN2,NR2C2,PRMT8,ZKSCAN5,FLRT2,P2RY12,ZFP37,KCNT2,AGMO,KCNAB1,RNF146" Coexpression M8313 Genes down-regulated in activated T cells: CD4 [GeneID=920] versus NKT. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD3,DGKZ,NCOA1,CALM1,ENTPD6,TPP1,SEC31B,RBM39,SGSM2,DNAJB6,TNK2,EIF1,RASGRP2,SH3YL1,TAOK3,ST3GAL6,FCGRT,ARFGAP2,SARAF,FYB1,TRAF3IP2,KAT7,IL6ST,IL11RA,ITPKB,JAK1,AFF1,MXI1,NUCB2,NUMA1,PDE4B,PDE4D,HERC2P3,SNRK,RFX5,RPL38,SATB1,SGK1,KDM3A,NSFL1C,MGRN1,TPM2,TSN,TSC2,TUBA1A,CIAPIN1" Coexpression M6636 Genes down-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus IL6 [GeneID=3469] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "MTUS1,APP,CCAR2,ASIC3,TAOK2,TBPL1,RNF14,CD99L2,RCAN1,ST8SIA3,SEZ6L2,EDNRB,ABI2,FAM198B,AKAP3,GABRA3,ERAP1,ADAM28,SLC2A6,C5orf24,MSR1,CDK18,RETREG1,SLC25A23,FAT3,KANSL1,PRR5L,RPS6KA2,BTBD3,FNBP1,ARHGAP26,SPTB,ITPRID2,STXBP1,SYT11,C3orf70,DNMBP,TBL1X,SPX,ZMAT3,AKTIP,TIAM1,SPIRE1,SLC30A4,SLC38A1,ST7" Coexpression M7186 Genes down-regulated in transitional CR2 [GeneID=1380] high B lymphocytes versus those from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD1,ADD3,GRAMD1B,SFMBT2,MADD,ARNTL,MTMR3,CBR1,FAM189A2,AKAP12,GUCD1,DNM2,DOCK2,SLC12A6,TACC2,HVCN1,FYN,GGT7,GLDC,KCNMB4,RFFL,PSIP1,ADAMTS6,IL6ST,INPP5B,KCNH2,IDNK,SMOX,POU6F1,PRKCZ,CEP97,OXR1,GTDC1,CCDC82,SELL,RASA3,STX1A,RHBDL3,KIAA1107,TBCEL,LRRC8A,RUNDC3B,MEIS3,PCBP4,ADAMTS10,FRMD6" Coexpression M6655 Genes up-regulated in bone marrow-derived macrophages at 45 min of stimulation by IL10 [GeneID=3486] and LPS: IL6 [GeneID=3469] knockout versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "XKR4,APBB2,ATP1B3,CRMP1,TENM4,PHACTR3,DAPK1,RUSC2,KIAA0319,DLG3,FEM1B,ABI2,PLEKHA1,CD320,FAM198B,SPSB4,FLNC,TACC2,DOT1L,GABRA3,ATP8A2,MALT1,SLC2A6,PRKCB,CNNM2,PTPRE,MARCH1,KCTD17,RTKN,RYR1,FOXRED2,SATB1,ITSN1,CLSTN1,SAMSN1,STXBP1,MCF2L,PSD3,C18orf54,CBX5,UCHL1,CLDND1,PMEPA1,TMEM163,AMN1,FRMD6" Coexpression M7135 Genes up-regulated in wildtype splenic dendritic cells: CD8A+ [GeneID=925] versus CD8A- [GeneID=925]. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AK2,CACHD1,SLC4A4,ADGRB1,BCHE,FMNL3,CBFA2T2,CD38,CPNE6,DNAJB5,CYBB,DDX46,ABCC5,COPS4,PLEKHA1,VPS26C,FABP7,FGF14,AHCYL1,TUBGCP4,GPR162,CRCP,HP,SMAP1,RBPJ,IL12A,CD200,IDNK,NODAL,NTRK3,OLR1,CDK18,PDE1C,PPP3CC,UHRF1BP1,NKAIN1,RASGRF1,UBR7,RPS6KA2,FNDC3A,SLC22A4,KIF1B,FBXW11,TCEA1,PITPNB,SCG2" Coexpression M10029 Genes down-regulated in NK cells versus CD8A [GeneID=925] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "DPF1,ASPHD1,RNF157,SLC12A5,MARCH4,MYH7B,PPFIA2,ASCL1,MYRF,TBRG4,CNTN1,RIMS4,HS3ST2,SEZ6L2,PHF20L1,USPL1,ENPP6,STMN2,GRM3,ATOH8,METTL21A,KCNN2,KHK,HECTD2,LYRM9,NDP,PDE1C,SEMA5B,RAB39A,GDPD1,SIDT1,RGS7,PRIMA1,DRAXIN,TMEM200C,SCN3B,PEG10,RAP1GAP2,FAM168A,AZIN2,CHST8,GPR161,LRTM2,FSTL5,KCNAB1,DPF3" Coexpression M6193 Genes down-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "RNF157,SYT13,CACHD1,CDC14B,CCDC181,DDR1,CACNB2,ARHGAP24,LONRF1,DNAL1,DNAJC6,RHOBTB1,DMPK,CD99L2,SLC43A2,EFS,ETV1,FOXM1,TMEM107,TPPP,SHISAL1,DOCK7,LIG4,AFF1,MYO9A,PLCD1,PMP22,SEPT4,MAPK10,CNTLN,PTPN13,PTPRE,RBBP8,MSANTD2,PPM1E,BEX1,IQSEC2,SEPT8,TMEM150C,TCF4,ATP13A2,THRA,CDK20,VLDLR,ZNF711,GDPD5" Coexpression M4344 Genes up-regulated in comparison of TregCD103+Klrg1- versus TregCD103+Klrg1+ (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AMPD3,DPP10,MAP4K3,BCAS1,FUBP1,AKAP5,ARHGEF10,PDE4DIP,PHYHIP,RABGAP1L,PLXNC1,RGS17,F8,PRKAG2,HTATSF1,FUT10,KIF3A,ADAMTS6,GUCY1B1,RASSF8,GPR45,SYNPO,KCNH2,MBP,MGAT3,NFIX,ZNF827,TMEM38A,MAPK9,SNRK,SELL,SCG5,FAM102A,CPEB3,PDZRN3,EMC1,STX1A,ARC,MCF2L,PCDHB15,FRYL,TIAM1,TRIO,TUBB2A,DHX33,SLC4A10" Coexpression M9697 Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 30h. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "OSBPL1A,ALCAM,CASK,CANX,SYT6,CCNT1,B4GALT6,CHRNB2,CLOCK,ABCG1,E2F5,TSPAN5,AASS,C8orf37,TUBB3,SORBS1,SARAF,GAB1,ADAM28,DBF4,GRIK5,KIF3A,GSTM5,PSIP1,SYNPO,IRF8,RBPJ,KCNQ2,MATN2,DDX25,NKX2-2,PAX6,SMIM7,CYBC1,RET,RNASE1,WLS,SLC1A2,SLC12A4,INTS9,ATP11A,ZEB1,TSC2,ZIC2,ZFAND5,GDPD5" Coexpression M4456 Genes up-regulated in comparison of memory IgM B cells versus plasma cells from bone marrow and blood. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ADD3,BIN1,APC,DGKD,APP,SLC4A4,SEPT7,LY86,NSL1,CSF1,PPP1R16B,RIPOR2,ARHGAP24,SACS,CASP8AP2,FRY,SIDT2,TENM1,RASGRP2,STRADA,GABBR1,PRRC2B,BACH2,ELOVL5,IRF8,NASP,OPA1,OPHN1,PIK3CD,SNX10,MINDY2,PRKACB,PKIA,PRKCB,MARCH1,RAP1GDS1,RADX,RFX5,RPS20,KIF13A,RBM34,KIF21B,POGZ,SYPL1,RALYL,KAT6A" Coexpression M6583 Genes down-regulated in monocytes: untreated versus CSF1 [GeneID=1435] knockout at day 3. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "ZNF608,GPRASP2,PKP4,API5,PDXK,P2RX6,ARHGEF2,EPS15L1,SUMF2,NCOR2,ABCG1,CS,PUM1,DLG2,EBI3,EIF4G1,TNK2,CHST15,ZCCHC17,DOT1L,WASHC2A,PRRC2B,RNF165,PADI2,ACOT7,MSL1,ADAM11,LRP1B,NODAL,VWA2,ARMC5,SLN,UNC5B,WWC1,CLASP1,AKNA,TP53BP1,TPM3,ZNF346,TRIO,MICAL1,TUBA1A,VPS35L,RGS7BP,TTC7A,SLC39A12" Coexpression M9337 Genes down-regulated in marginal zone B cells versus day 7 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.30E-03 1.00E+00 2.32E-02 2.31E-01 46 200 "AXIN2,SEMA6A,PITPNM2,PPFIA4,ASPH,RGS9,CH25H,ASIC3,CLTA,CSF1,ST18,PYGO1,ARHGAP24,RAB39B,FAM198B,SORBS1,BRSK1,GFAP,FUT10,GRM2,PTPN5,BVES,HAS2,HRH3,HMX1,TLX1,RCOR2,SEMA5B,TMIE,PMP22,RELN,SIDT1,RFX4,ZNF532,PAQR6,SCN2A,CCDC92,LIMS2,SORCS3,ZHX3,SYT5,LEFTY2,PPIL6,OSBP2,PLEKHH2,ZIC3" Coexpression M2378 Genes down-regulated in hypertrophic hearts (due to expression of constitutively active form of PPP3CA [GeneID=5530]) and predicted to be targets of miR-133 microRNA. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.31E-03 1.00E+00 2.33E-02 2.31E-01 5 8 "ASPH,MEF2C,PRRX1,BTBD3,PUM2" Coexpression M1269 Genes down-regulated in ESFT cells (Ewing's sarcoma family of tumors) after knockdown of CD99 [GeneID=4267] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.31E-03 1.00E+00 2.33E-02 2.31E-01 5 8 "BCL2L2,RABGAP1L,EBF1,HIPK3,KIF21B" Coexpression M1992 Genes up-regulated similarly in primary fibroblast cultures from Werner syndrom patients and normal old donors compared to those from normal young donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.33E-03 1.00E+00 2.35E-02 2.33E-01 25 93 "ADD1,ADGRF5,SEMA7A,ARHGAP5,NRXN2,ARMC8,ENTPD4,CTNND2,EDIL3,FECH,STAMBP,GABRA2,NUDT21,SHISAL1,KTN1,MARK3,MBD1,MYCN,NOVA2,PRKAB2,PRKAR1B,PTCH1,GTDC1,TCF7L2,TCF12" Coexpression M2062 Top 20 negative significant genes associated with malignant fibrous histiocytoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.35E-03 1.00E+00 2.35E-02 2.34E-01 8 18 "COL4A5,TENM4,CAP2,BRPF3,GNAS,OBSL1,DDHD1,ITM2C" Coexpression M10387 Top 20 positive significant genes associated with synovial sarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.35E-03 1.00E+00 2.35E-02 2.34E-01 8 18 "APBA2,KIF1A,COL9A2,RGS6,OLFM1,KCNQ2,NPTX2,ZIC2" Coexpression 18722011-SuppTable2n Human Leukemia_Sanchez-Guijo08_62genes GeneSigDB 3.38E-03 1.00E+00 2.37E-02 2.36E-01 18 60 "AP2A2,ANXA7,ATP2B1,ATP2B2,BCS1L,CACNB2,AKAP6,RIMS3,TOMM20,DNAJB6,ABCC5,PSRC1,SCAMP5,MYL3,FOXRED2,VAMP1,SLC30A3,KCNAB1" Coexpression M2676 Genes up-regulated in HUVEC cells (endothelium) by treatment with VEGFA [Gene ID=7422]. MSigDB C6: Oncogenic Signatures (v6.0) 3.39E-03 1.00E+00 2.38E-02 2.36E-01 45 195 "SERPINA3,TKTL1,ADORA2A,PPFIA4,PLA2G4C,CFAP410,LOC730101,UBE2L6,LHX2,FAM189A2,IQCK,CABP1,COL11A2,AKAP5,CLIP3,PPP6R2,SPOCK3,DLG2,OPTN,ENO2,CORO2B,AKAP3,GABRA5,TMEM8B,GRIK2,HTR2A,MATN2,MN1,LYRM9,NCF2,ENPP2,PKD1,PLTP,RGS3,SH3BP2,SLC12A2,ZCCHC24,ARC,SMG6,KIAA0930,TNS2,TLL2,TUB,AMOT,CLIP2" Coexpression M8858 Genes up-regulated in lymphoid primed multipotent progenitors versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.39E-03 1.00E+00 2.38E-02 2.36E-01 45 195 "PARG,CCDC181,WASF1,ARHGEF6,COL9A1,HDAC4,EDIL3,EEF1A2,SEMA3D,EFNA2,EN2,TLR7,CACNG2,SEC23B,FLT1,TACC2,GABRA3,GATM,DIDO1,GRM3,ADAMTS6,GUCY1A1,TLX1,MSL1,KCNA4,SHC3,SCAMP5,MYH3,RETREG1,TRHDE,RAVER2,WLS,STUM,RIMS1,MYO16,MCF2L2,POGZ,CNTN2,ADGRL3,SIN3B,ZNF384,CA14,PORCN,RNF103,UBE3B" Coexpression 19861896-Table2 Human Brain_Castells09_83genes GeneSigDB 3.42E-03 1.00E+00 2.40E-02 2.38E-01 21 74 "ALCAM,RIPK1,CDH2,CDH10,JAM2,RAB33A,DSCAM,LPAR6,TUBB3,GPR153,NEK6,TUBA8,PCDH17,GHR,GPM6A,GPR17,NCAM2,PCDH9,PDGFRA,PRKACB,TEK" Coexpression M14702 Genes up-regulated in gastric cancer patients refractory to chemotherapy treatment with 5-fluorouracil and cisplatin [PubChem=3385;2767] compared to the sensitive state. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.45E-03 1.00E+00 2.41E-02 2.40E-01 27 103 "PPFIA1,PPFIA3,N4BP2L1,CFAP410,AATK,DCAF8,B3GAT3,EPHB1,FABP7,BAIAP2,TMEM8B,GLYR1,PSRC1,ADAMTS8,MYO7A,NCAM1,NME4,SLC11A2,PLXNB1,POLG,PCDHB17P,PPP3CC,RGR,KDM4B,SOX15,TMEM151B,CRTC1" Coexpression M9141 Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus SATB1 and FOXP3 [GeneID=6304;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.47E-03 1.00E+00 2.43E-02 2.41E-01 32 128 "KCNH8,SEMA4G,IGDCC4,MARCH3,C1QC,THSD7A,COL9A1,SLC45A1,CX3CR1,APC2,FER,FGF12,ACTL6B,FGR,CIT,SYNPO,DISP2,C2CD4C,KCNA4,TAGLN3,P2RX7,CDK18,SLC10A4,SCHIP1,RANBP3L,SNCB,C11orf87,TIMP4,TLL2,TNS1,NPL,ZBTB16" Coexpression M2746 Genes up-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes. MSigDB C6: Oncogenic Signatures (v6.0) 3.48E-03 1.00E+00 2.44E-02 2.42E-01 44 190 "PPFIA4,ARSF,MYOM1,BMP7,CACNB2,MAP7,GPR37L1,PLAA,CLCN4,DGCR9,ARMC8,CRMP1,CLIP3,RIPOR2,RASSF2,DRD1,ECM2,ELN,RASSF8,GPR45,LINC00667,KCND3,KCNJ5,KCNJ9,KCNN3,MAN2A2,SHC3,MMP17,PDE4B,PHKG1,NLE1,RAD17,SCN2B,MRAS,SLC6A1,EFHD1,RGL1,TACR1,AGTPBP1,SYNE1,TEK,TSN,SLC26A10,EPM2A" Coexpression M8857 Genes up-regulated in UB27 cells (osteosarcoma) at 8 hr after inducing the expression of a mutant form of WT1 [GeneID=7490]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.53E-03 1.00E+00 2.47E-02 2.45E-01 39 164 "ABAT,ACTN1,ARHGDIA,MARK4,ATP1A2,ATP2B1,SYNJ2,CA12,B4GALT6,DNAJB5,QKI,CSF1,SIRPA,PLEKHO1,ENO2,FGF1,FGFR1,BAIAP2,AHCYL1,CSDC2,RAB40B,GRB10,HSP90AA1,IL6ST,AFF1,NBL1,PIK3CD,PLEC,PPP3CA,PTHLH,RIPOR1,RGS4,SON,DOK5,ARC,SYNE1,SLC35G2,DICER1,TNS1" Coexpression 16440291-SuppTable1 Human HeadandNeck_Martens06_209genes GeneSigDB 3.54E-03 1.00E+00 2.47E-02 2.46E-01 47 206 "ADGRF5,SPARCL1,SGCE,IL33,LDB2,AKAP12,CST3,SDC3,GPRASP1,CHRDL1,EDNRB,FAM13A,RASA4,EPS8,NRN1,F8,DLC1,FCGRT,IQGAP2,GHR,LYVE1,FERMT2,GUCY1B1,IGF1,IL6ST,IL11RA,MATN2,FXYD6,P2RY13,NELL2,PDE2A,PLTP,PMP22,LRRN3,PTPRE,RNASE1,ZCCHC24,ZNF423,RGL1,ZFPM2,TGFBR3,TIE1,TNS1,TPM1,FLRT2,ZBTB16,PLSCR4" Coexpression M19993 "Up-regulated genes in B-CLL (B-cell chronic leukemia) patients expressing high levels of ZAP70 and CD38 [GeneID=7535;952], which are associated with poor survival." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.57E-03 1.00E+00 2.50E-02 2.48E-01 60 276 "ABR,SRPX,OGT,CDK10,ARHGDIA,ZSCAN18,LDLRAD4,ARHGEF1,CD38,CNR1,AKAP12,NCAN,DAPK3,IP6K1,SGSM2,DMD,DNM2,DPYSL2,PLXNC1,ERBB4,PIPOX,ARMCX1,FGFR1,PNMA2,GAA,NCKAP1,SEPT9,GATM,GLUL,LILRB4,RAPGEF1,ADAMTS6,MAN1B1,IL6R,MEST,MX1,NCF2,NPTX1,NUCB1,NUMA1,OGDH,PDE3B,SERPINE2,FA2H,PPP2R2B,ZSCAN32,ROGDI,RNH1,RXRA,RYR3,IL17RB,SPART,ATP11A,TRIM2,PSD3,TGFBR3,TNFRSF1B,CABIN1,SH3GLB2,SLC4A10" Coexpression 18631401-TableS3 Human Breast_Yau08_1518genes_OxidativeStress GeneSigDB 3.58E-03 1.00E+00 2.50E-02 2.48E-01 208 1129 "NDRG2,ADD3,MTUS1,KIAA1324,AK2,ALAD,SPOP,BEGAIN,AMPD2,ANK3,APBB2,SHROOM2,TMEFF1,ARNTL,RGS20,ASCL1,ASPH,NCOA1,ALDH4A1,ATM,ATP2A2,MTMR2,GYG2,SGCE,OSGIN2,RAB29,CA12,CARS,LRBA,CDH18,FOXN3,CNOT8,LHX2,ABCG2,QKI,RAB26,AKAP5,SLC4A7,MYRIP,NSL1,ABCG1,CSNK1E,PDE4DIP,DZIP3,CTNND2,HDAC4,TBC1D5,DAPK1,LYPD1,RABGAP1L,DLG3,DMD,USP3,DTNA,DNAJB6,ABCC5,E2F5,EDN1,SEMA3D,EFNA3,RBM12,EFNB3,FAM13A,EGFR,EGR3,EIF5,ING4,PCOLCE2,EIF1,VPS13B,ERBB4,GMPR2,F3,ARMCX1,EFEMP1,ATP8A1,TESK2,FECH,FGF13,PRKAG2,CAMSAP1,FHL1,CAP2,PCYOX1,EFCAB2,PDLIM5,TPK1,PRELID3A,OGA,GAD1,ZNF274,MTHFD2,GATM,GFRA1,GHR,RND1,TOX3,PSRC1,GPR19,STON1,GPER1,RNFT2,HMGCR,IL6R,INPP1,ITPKB,JAK2,KLC1,MAP2,MEIS2,KITLG,MID1,THYN1,N6AMT1,MXI1,MYCN,NASP,NCAM2,NEK1,NFE2L2,SLC11A2,NUMA1,SETD4,PBX1,PCDH9,PDCD2,PDE3B,CDK14,SERPINE2,PIK3R1,NLE1,PLCL1,SMOX,PMP22,LRP12,NECAB2,PPP2R5C,PKIA,MAPK10,SYTL2,ELOVL2,PTPN13,PTPRE,PEX5,TMEM231,RAP1GAP,SUSD4,RBBP6,RFX5,UBR7,ZNF532,STK32B,SATB1,ATXN1,SFPQ,HSPA4L,SGK1,SYBU,KBTBD4,SLC12A2,SLC15A2,SLIT1,SMARCC2,SMARCE1,TTC17,PALLD,PDZRN3,SOX2,SOX3,GLT8D1,UHRF1BP1L,CDK19,LMO3,ITPRID2,LARP4,STX1A,KANK1,JMJD6,ARC,SYT1,ASTN2,POPDC3,TACC1,CAMTA1,MCF2L,DNMBP,OBSL1,SIK3,CDK20,TRIO,RUNDC3B,SSBP2,TUBB2A,SGK3,CADM1,UCHL1,DNAJC12,CLDND1,ZBTB14,ZNF23,REEP1,ZNF195,ZFAND5,LRP8,CAB39L,TRIM16L,ST7,ZNF248" Coexpression M14242 Genes trans-regulated by the same QTL (quantitative trait loci) in brain and hematopoietic stem cells (HSC). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.58E-03 1.00E+00 2.50E-02 2.48E-01 43 185 "NCOA1,BLM,SGCE,ZMYM4,EPS15L1,ZFYVE16,DNAJB6,ASB3,EIF4G1,DMTN,SALL3,GLDC,STMN2,IGFBPL1,HP,KCNN1,MKLN1,MMP17,MOV10,MSI1,NRBP2,MYH3,SFR1,NEK1,NF1,EPB41L4B,PPARA,PKIA,PSD,RAP1GDS1,SFPQ,ST8SIA1,TTC17,KLHL7,ZFR2,VAMP1,SYPL1,USP22,NSD1,UBC,TBC1D15,ZBTB14,MAP3K12" Coexpression 17191107-Table1 Human Lung_not_cancer_Gambardella06_38genes GeneSigDB 3.66E-03 1.00E+00 2.55E-02 2.54E-01 12 34 "SLC4A4,CANX,CLCN3,GRM8,NDUFA5,PTPA,PPP3CA,PRKCG,SGK1,SNAP25,STX1A,GOPC" Coexpression M6776 Genes down-regulated in splenic DEC205+ dendritic cells versus CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.68E-03 1.00E+00 2.56E-02 2.54E-01 37 154 "ADCY6,TMEFF1,ZBTB10,SYNJ1,CACNB2,CX3CR1,ACY3,ARMCX4,EPS8,FHL1,FYB1,NEK6,GCNT2,AHDC1,GFRA1,LPAR4,GRIK5,KCNH2,LDLRAD3,MOV10,NNAT,PCBP3,SLC25A23,TMEM104,CCDC40,MEG3,SH3GL3,CPEB3,ZFR2,SYNE2,UNC5D,USP22,ZMAT3,CHST5,TRPS1,LRTM2,VANGL2" Coexpression M1102 "Genes down-regulated in ME-A cells (breast cancer, sensitive to apoptotic stimuli) upon serum deprivation for 22 hr in the presence of medium concentrate (MC) from ME-C cells (breast cancer, resistant to apoptotic stimuli)." MSigDB C2: CGP Curated Gene Sets (v6.0) 3.70E-03 1.00E+00 2.58E-02 2.56E-01 23 84 "AS3MT,PPFIA4,BCL2L2,SLC25A14,COPB2,UBXN2A,MED24,DNM1,DNAJB6,ENO2,GCNT2,CSDC2,GP1BB,KIF2A,NASP,ODF2,EPB41L4B,ATXN7,LHPP,THSD1,TPD52,TPM3,PORCN" Coexpression 19808870-ST3 Human Breast_Speers09_24genes GeneSigDB 3.71E-03 1.00E+00 2.58E-02 2.56E-01 9 22 "NME5,DDR1,DCLK1,FGFR1,FGFR3,NBEA,STK32B,SGK3,MAP3K12" Coexpression M16050 Upregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys MSigDB C2: CGP Curated Gene Sets (v6.0) 3.73E-03 1.00E+00 2.60E-02 2.58E-01 54 244 "SERPINA3,MADD,ASPH,STX16,ATP6V0A1,CALB2,CBS,RAB33A,CLTA,CSF1,RUBCN,DLG3,ATN1,MAMLD1,EFNB3,ELAVL2,CALCRL,FOXF2,FLT1,TBR1,GCNT2,BTN2A1,GUCY1A2,JAK1,KCNMA1,CHIC1,MPP2,NCAM1,NPR2,DDR2,PDE3B,PDE4B,PENK,PLXNB1,PCDHB17P,PPP3CB,MAPK8,RELN,PTHLH,PTPRN2,RFX5,RTN1,SH3GL3,ZKSCAN3,MAST1,RBM34,STX1A,MLC1,TPD52,UBC,VSNL1,SLC30A3,LIFR-AS1,SCG2" Coexpression M5218 Genes bound by EWSR1-FLT1 [GeneID=2130;2321] fusion but whose expression did not change in STA-ET-7.2 cells (Ewing's sarcoma) after knockdown of EWSR1-FLT1 by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.75E-03 1.00E+00 2.60E-02 2.59E-01 15 47 "ZFAT,ARNT2,CHL1,TNRC6A,GRID1,LRP1B,HS6ST3,NEK1,PTPRD,RIT2,GALNT10,ERC1,HEY1,ANKS1B,KCNAB1" Coexpression M4685 Genes down-regulated in comparison of CD4 [GeneID=920] effector memory T cells versus CD4 [GeneID=920] central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.75E-03 1.00E+00 2.60E-02 2.59E-01 45 196 "SERPINA3,ACTN1,GPRASP2,SFMBT2,SPTBN4,N4BP2L1,BBS2,BAG4,AKAP12,PLXNA4,FAM78B,ARMCX1,RAB30,GLS,ZNF638,CECR2,GRM7,HSF2,SESN3,LYRM9,RETREG1,NLE1,SPATA6,DRAM2,NKAIN4,ZNF844,ENOX1,RPRD1A,GSTCD,ADAL,TRAPPC13,FAM19A1,SLC4A3,SLC15A2,ZFP1,FAM126B,DOK5,GANAB,TRIM2,CHST5,CLHC1,ZNF138,RNF103,PDSS2,SSPN" Coexpression M7571 Genes down-regulated in CD11b BoneMarrow from BALBc mouse versus CD11b BoneMarrow from BALBc mouse incubated with GMCSF and GCSF. MSigDB C7: Immunologic Signatures (v6.0) 3.75E-03 1.00E+00 2.60E-02 2.59E-01 45 196 "ADD1,ZNF608,TMEM263,ZBTB10,WASF1,CD86,ABCG2,MAGED1,CRYM,MBNL2,MRNIP,CORO2B,CAP2,SYNCRIP,JKAMP,KIAA1958,GNG3,LILRA2,RNFT2,GUCY1A1,IGSF21,ITGAM,KIF2A,PAXBP1,MIA2,NPY,NPTX1,ODF2,PIK3CD,SMIM7,PLTP,MAPK8,UHRF1BP1,PTPRE,ENOX1,C12orf49,ROBO1,BTBD3,RAP1GAP2,ARHGEF9,SSBP2,UBE2H,TMEM178A,AMN1,NLRP3" Coexpression M5141 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection. MSigDB C7: Immunologic Signatures (v6.0) 3.75E-03 1.00E+00 2.60E-02 2.59E-01 45 196 "NCKAP5,ELFN2,ANK1,MYH7B,ALDH4A1,RNF182,GPR146,SLC16A4,FBXO7,ABCG2,TCEAL2,HS3ST5,MICAL2,DNAJC6,GUCD1,EBF1,EPB41,ZNF461,FECH,ACSS1,RUNDC3A,GNG3,GRIN2C,GABARAPL2,LRRC4B,MATN2,SESN3,MXI1,PFKFB2,BDNF-AS,RAP1GAP,TUNAR,SLC4A3,SLC6A8,SLC14A1,SNCA,ZNF423,SPTB,CNTN2,GPR161,TMOD1,TNS1,TRO,PMEPA1,MARCH8" Coexpression M3112 Genes down-regulated in comparison of effector memory T cells versus central memory T cells from peripheral blood mononuclear cells (PBMC). MSigDB C7: Immunologic Signatures (v6.0) 3.75E-03 1.00E+00 2.60E-02 2.59E-01 45 196 "ACTN1,MTUS1,TAOK1,GOLGA7B,EP400,APBA2,ATM,ATP1A1,CACNA1I,LDLRAD4,KALRN,CBS,NOG,MAP4K4,IPCEF1,KLHL3,AK5,FAM13A,TENM1,F5,GRIK5,LINC01089,LINC01550,IL6ST,GPR155,SESN3,MIR4697HG,PDE3B,PKM,PPP3CC,PTK2,TUG1,GAL3ST4,SELL,FRMPD1,CNKSR2,TNIK,MYCBP2,CEP68,TBL1X,TCF7,PCDHB3,AMN1,KAT6A,CERS6" Coexpression M1542 Genes up-regulated in embryonic stem cells from TCEB3 [GeneID=6924] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.77E-03 1.00E+00 2.61E-02 2.59E-01 41 175 "SEMA6A,APP,SFMBT2,BACH1,SGCE,CALM1,KALRN,CD38,CLU,FAM189A2,COL4A5,CST3,YAF2,MBNL2,F3,AMOTL2,STARD10,GGTA1P,GHR,TCERG1,MSL3,GLUL,GNAS,KIT,MYH6,MYL3,PDE1B,LAMA1,PTH1R,SEMA6D,FNDC3A,FHOD3,LMBRD1,EPB41L3,GANAB,TCF7L2,DOCK9,CYB561A3,TST,SLC38A1,RSPRY1" Coexpression 20035825-TableS7b Human Lung_Mikkonen10_209genes GeneSigDB 3.77E-03 1.00E+00 2.61E-02 2.59E-01 41 175 "DPY19L2P4,NR0B1,SYT13,BCAS1,ASGR1,BCL7A,BMP7,SLC5A11,LHX2,RAB26,COL9A3,SLC4A7,KIF26A,RASSF2,AIF1L,TMEM130,EBF1,EDN1,PDLIM5,GPR162,KIRREL3,EML4,SOX21,FRMD5,C2CD4C,KCNK3,NEFH,NRGN,FSD1,NKAIN4,SYTL2,PTHLH,RAP1GAP,SLC1A7,SLC12A2,SOX2,SMOC1,RHBDL3,SYT1,FLRT2,MGAT5B" Coexpression 16239301-SuppTable2b Human Breast_Harvell_68genes GeneSigDB 3.78E-03 1.00E+00 2.61E-02 2.60E-01 17 56 "SEMA6A,ALCAM,SLC4A4,ST3GAL5,JAM2,RAB26,FGF12,GAB1,FICD,PIK3R1,PRRX1,BCAS3,SMARCE1,MBD5,ZSWIM8,ACSL6,MAP3K12" Coexpression M1988 Genes associated with resistance to mitoxantrone [PubChem=4212]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.78E-03 1.00E+00 2.61E-02 2.60E-01 17 56 "ABI3BP,DOCK2,ELAVL4,EPB41L2,SDCBP2,PTPN5,RASSF8,ELOVL5,LAMA2,IRX1,SYTL2,CASC3,SMARCE1,POPDC3,UNC5D,SLC30A4,PPP1R3F" Coexpression 19893992-Table1 Human Viral_Bellodi-Privato09_58genes GeneSigDB 3.78E-03 1.00E+00 2.61E-02 2.60E-01 17 56 "ALS2,CAMK2G,NDST3,CS,DOT1L,GALNT15,GAD2,GRM1,HPSE2,ITGAV,NEFM,PHKG1,PPP3CA,PRKAR1B,SLC8A1,SIRT2,TCF7" Coexpression 16760442-SuppTable5-1 Human Lymphoma_Hummel06_50genes GeneSigDB 3.80E-03 1.00E+00 2.62E-02 2.61E-01 11 30 "BMP7,WASF1,PTBP2,BACH2,NASP,FHOD3,SMARCA4,SOX11,SSBP2,UCHL1,PRDM10" Coexpression 15358818-table1 Human Stomach_Yuan04_32genes GeneSigDB 3.80E-03 1.00E+00 2.62E-02 2.61E-01 11 30 "ARHGEF7,PNKD,DCTN1,TNK2,TUBB3,DCTN2,GNAL,HSPA1L,SMARCC2,SPTAN1,SYNE2" Coexpression 15892885-tableS1c Human Prostate_Chandran05_101genes_Tumor _v_AdjNormal GeneSigDB 3.81E-03 1.00E+00 2.63E-02 2.61E-01 24 89 "ACTN1,CALM1,LARGE1,CHRDL1,SH3GLB1,RACK1,FLNC,NPTN,GJB1,FERMT2,ATXN2L,IL6ST,MEIS2,RAP1GAP,RGS10,SMARCD3,PALLD,ZCCHC24,TACC1,DDHD2,NACC2,TPM1,TPM2,TUBA1A" Coexpression 19658189-TableS9b Human EmbryonicStemCell_Xu09_100genes GeneSigDB 3.81E-03 1.00E+00 2.63E-02 2.61E-01 24 89 "ACTN2,ADRB2,MYH7B,BMP7,JAZF1,CAMK2D,CDH2,RNF14,CPEB2,DTNA,TMEM25,ITGAV,JAK2,MYH6,MYH7,MYL3,NPPA,MYO18A,PALLD,TLL2,TMOD1,TPM1,TPM2,MSRB3" Coexpression 17880687-Table2 Human Embryo_Heim07_40genes_ChangedBasallyRIP140 GeneSigDB 3.83E-03 1.00E+00 2.64E-02 2.63E-01 10 26 "BACH1,PTBP2,CDC42,HECTD1,B3GAT3,UFM1,GCNT2,GPD2,ZNF655,FNIP1" Coexpression M1047 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing inv(16) translocation. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.84E-03 1.00E+00 2.65E-02 2.63E-01 86 421 "ACTN1,ADCY6,BIN1,DGKD,ATP2B1,BCL2L2,ARHGEF7,OSGIN2,CACNA1D,HAP1,AIFM1,LGI1,CDR1,COPB2,CBARP,CNOT8,IQCK,SLC4A7,CPS1,RBM39,CLIP3,CSNK1E,PPP1R16B,ST18,DOCK4,TM9SF4,DGKB,FBXL5,DLG2,DMD,DTNA,DYRK1A,EGR3,ERBB4,FKTN,CAP2,FLT1,TBR1,GAB1,ADAM28,USP19,DIDO1,NR3C1,HNRNPK,TUBB2B,KPNA5,MEST,MN1,NACA,NF1,OPCML,PAK3,PCDH8,PCMT1,PFKP,MTRF1L,PMP22,SCHIP1,PTHLH,ELOVL2,PTPRE,RIT2,RPS20,SCAF8,SH3GL2,SLC6A11,IGSF9B,MAPKBP1,SOX2,SPP1,ZBTB43,ITPRID2,VPS13A,TACC1,ACSL6,ARHGEF12,ICAM5,TLL2,TST,UBC,FLRT1,XRCC4,ZIC1,ZNF23,ATP6V0E2,LRP8" Coexpression 12747878-Table3 Human Breast_Huang03_164genes_recurrence GeneSigDB 3.86E-03 1.00E+00 2.65E-02 2.63E-01 34 139 "ASIC2,AP2A2,ARHGDIA,SLC22A6,CPNE6,CSF1,RUBCN,PHYHIP,EFNA3,ELAVL2,FOXG1,GABBR1,GRM2,ITGAV,MAG,OPRL1,PDPK1,PPP2R5E,PSMD13,PTPRD,RAP1GAP,RPH3A,SLC6A7,IGSF9B,FAIM2,SPTB,ATP10B,ST5,SYN1,CNTN2,CLASP1,GPR161,KCNAB1,UBE3B" Coexpression M8931 Genes down-regulated in CD4 [GeneID=920] Th17 T cells: enriched versus negative. MSigDB C7: Immunologic Signatures (v6.0) 3.86E-03 1.00E+00 2.65E-02 2.63E-01 40 170 "NDRG3,HACE1,AMH,CAMK2D,CCPG1,ABCG2,HAPLN1,FGFR1OP2,FAM107B,ABI1,TOM1,ABCC5,TMEM35A,CHST15,GTF2IRD2,IP6K2,PDLIM5,ACSS1,KIF3A,CLASRP,PDE2A,PDE3B,PPP2R5E,SLC26A11,RAD51D,ST8SIA1,SLA,DHX30,SLC12A4,DIP2A,MLST8,SIN3B,ARHGAP9,KCTD2,RUNDC3B,SLAIN1,WRN,PARP11,RTN4,SPATA13" Coexpression M2942 Genes down-regulated in gamma delta intraepithelial lymphocytes from colon: control versus colitis induced by dextran sulfate sodium (DSS). MSigDB C7: Immunologic Signatures (v6.0) 3.86E-03 1.00E+00 2.65E-02 2.63E-01 40 170 "ACTN1,ADCY6,INTS2,USP28,ZBTB10,SCAPER,FOXK1,BTF3L4,IPCEF1,HDAC4,TOX,E2F6,PLEKHA1,PLEKHO1,CHST15,SESN1,TDRKH,RAPGEF4,ELOVL5,IL6ST,SMAD1,SESN3,MTR,SLC11A2,CEP97,BEND5,RGS10,SELL,MAGI3,ST6GAL1,ST8SIA1,DZIP1,SCMH1,TET1,SON,TNIK,CEP68,SSBP2,TTC3,KLHDC1" Coexpression M8885 Genes up-regulated in hematopoietic stem cells versus NK cells with RAG2 [GeneID=5897] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.86E-03 1.00E+00 2.65E-02 2.63E-01 40 170 "AS3MT,ADD3,MARCH3,RGS9,BAIAP3,ARHGEF1,CNN3,ATRNL1,SIPA1L1,DOCK4,RIPOR2,RASSF2,ARMCX2,KBTBD11,CHST15,FGF13,AP4B1,RAPGEF6,STARD3,RAPGEF4,AGFG1,KCNA2,KCNH2,SESN3,NACA,PDCD2,PDE4B,PIK3CD,PACSIN1,SH3KBP1,SLC26A11,SATB1,SLC14A1,CAND2,SS18,TGFBR3,ZMYND8,SSBP2,PARP11,VANGL2" Coexpression M9517 Genes up-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 8 versus day 15. MSigDB C7: Immunologic Signatures (v6.0) 3.86E-03 1.00E+00 2.65E-02 2.64E-01 44 191 "TMEM132B,SORCS1,AMH,APBB1,LINC00173,CHRD,ADGRB3,BLM,NRXN3,KIF26A,MRNIP,DACH2,GAP43,GPR37,RNFT2,KCNA2,KCNH1,MAPT,SYT9,SCAMP5,WDR11-AS1,NHLH1,NODAL,NLE1,BCAS3,PTH1R,VEPH1,LGI2,AMER2,OGDHL,SNAP25,MESP1,KLHL4,EHBP1,PCDHB7,VWCE,ANKRD24,PARD3,LILRA4,TUBA3FP,ZNF70,LINC02210,ITM2C,SSPN" Coexpression M18108 Genes both mutated and amplified in a panel of 191 breast tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.88E-03 1.00E+00 2.67E-02 2.65E-01 25 94 "CSMD3,ANK1,EP400,MYH7B,ARRB1,DNAH17,ADGRB1,CACNA1G,RIMS2,GOLGA7,VPS13B,ZNF461,FGFR1,AGAP2,GRIN2C,KCNQ3,MYO7A,SAMD9,SYTL2,ZFHX4,PPM1E,RADIL,ZCCHC24,SULF2,ARC" Coexpression M2029 Genes down-regulated in NCI-H1299 cells (large cell neuroendocrine carcinoma) stably expressing SEMA3B [GeneID=7869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.90E-03 1.00E+00 2.68E-02 2.66E-01 84 410 "SLC12A5,ADORA2A,C1QTNF3,ALCAM,CCDC146,DGKD,ALS2,ARRB1,RGS20,ATP2B1,CALB2,METTL6,INA,SYNGR3,NEURL1,LHX2,DLGAP3,SRP14-AS1,CCDC151,PDE4DIP,PNPLA8,HDAC4,AIF1L,NTM,DNAJB6,ATL1,KLHL5,PLEKHO1,EPB41L2,SH3YL1,C1orf61,SLC37A3,EFCAB2,KHDRBS3,GPR153,PHYHIPL,FAM120B,GNG4,SPACA9,LRRCC1,ITGAM,KIFC3,INSYN2,SRSF12,KITLG,ZNF862,NDUFA5,NEFH,NOVA1,DPY19L2P2,NECAB2,PPP2R2C,GON4L,ELOVL2,TTC13,ZDHHC14,RFX5,PRR5L,RIMKLA,NCBP3,MRAS,FAM102A,PPM1E,CCDC92,SLC6A8,EFHD1,CXXC4,SMARCD3,UHRF1BP1L,SRPK2,MESP1,FCHO1,INKA2,ZFR2,SYPL1,CAMSAP2,TCF4,AZIN2,TPM1,ELFN1,PLPP4,PMEPA1,NLRP3,FRMD6" Coexpression M440 Genes down-regulated in CAL1 cells (plasmacytoid dendritic cells) versus MOLT4 (immature T cells). MSigDB C7: Immunologic Signatures (v6.0) 3.90E-03 1.00E+00 2.68E-02 2.66E-01 33 134 "CSMD3,ANK2,ATP2B3,CARMIL3,CACNG1,CH25H,USP6NL,RIMS3,MED24,TMCC2,EPS8,TBC1D16,NBEA,GAP43,GCK,GPR17,C1QL4,CIT,ELOVL5,KCNJ11,KCNK2,KCTD6,BCO1,VWA2,MARCH1,ACSS3,RGS7,RTKN,CCDC112,POPDC3,LEFTY2,SEZ6L,PITPNB" Coexpression 16651414-Supp3 Human Breast_Bertucci06_534genes GeneSigDB 3.99E-03 1.00E+00 2.73E-02 2.71E-01 75 360 "ACTN1,ADORA2A,KIDINS220,ANXA7,CACHD1,DACT3,NCOA1,CBS,CD38,CD81,PNKD,C2CD2,CTNND2,CX3CR1,ECE2,BOC,PHF19,CNIH3,RCAN1,E2F5,EDNRA,ATL1,EFNA3,PCOLCE2,EPB41,ERBB4,SPEG,EXTL2,KATNAL1,MRVI1,DLC1,ATP8A1,PPP1R1B,FHL1,IQCG,FOXM1,FLNC,ATP13A4,GABBR1,ERAP1,COPS8,FERMT2,SLC2A6,GYG1,LAMA2,MDFI,MYO7A,NPR2,DDR2,PCDH18,CEP41,MAPK7,PTPRZ1,RFX5,RGS4,MCMBP,ATXN7,MAGI3,SLC4A3,SMTN,LIMS2,ZCCHC24,ZBTB43,MPRIP,DNAJC9,OBSL1,THBS4,TNFRSF1B,TPM2,TTC3,CADM1,VSNL1,NAV3,RTN4,MSRB3" Coexpression M19068 "Genes present but differentially expressed between Hep3B cells (hepatocellular carcinoma, HCC) with RNAi knockdown of SDHB [GeneID=6390] and control cells." MSigDB C2: CGP Curated Gene Sets (v6.0) 4.00E-03 1.00E+00 2.74E-02 2.72E-01 29 114 "ATP2B2,CLTB,IGDCC3,CREB5,MICAL2,HDAC9,GSDME,PCOLCE2,F5,FAXC,MATN2,PAH,PFKFB3,SERPINE2,SERPINI1,PRRX1,FAT3,SUSD4,KIRREL1,WLS,TNFRSF19,SCG5,HKDC1,SLC12A2,RAP1GAP2,APOM,TF,THBS4,LYPD6" Coexpression 12734205-TableS2 Human Ovarian_Wood03_445genes GeneSigDB 4.02E-03 1.00E+00 2.75E-02 2.74E-01 73 349 "AS3MT,SPARCL1,PPP4R4,TMEFF1,NCOA1,RASL11B,DOCK11,BID,NAE1,CAPN3,CBR1,DCLK1,NPIPA1,CLU,NMT2,LETMD1,CNRIP1,SIPA1L1,RASSF2,EDNRA,KLHL5,PLXNC1,TMEM35A,STARD3NL,LRRC23,KATNAL1,ACSL4,SMC2,KHDRBS3,PNMA2,RAPGEF6,RAPGEF4,IRAK3,HAS2,HMGCR,KLHL23,IPO5,LYPLAL1,MEST,CD200,GIT1,NEFH,SLC11A2,NTRK3,PDCD2,PLP1,MTRF1L,QDPR,FAT4,ERI2,RGS10,PRR5L,PRCD,NUBPL,LIMCH1,PDZRN3,SSTR1,FAM168A,FGD4,ATP11A,TAF6,TEK,HEY1,SSBP2,RFTN2,SLC35A4,UCHL1,FLRT2,BCL2L13,KCNT2,ZNF45,ZBTB38,FRMD6" Coexpression M9113 Genes down-regulated in CD4 T conv: control versus over-expression of IRF4 and FOXP3 [GeneID=3662;50943]. MSigDB C7: Immunologic Signatures (v6.0) 4.04E-03 1.00E+00 2.76E-02 2.74E-01 38 160 "ABCF1,SLC25A25,PNMA8B,AP2A2,TXNDC16,ALAD,ASPH,BCL7A,HIP1R,LRWD1,RTTN,CTNND1,PPP6R2,IP6K1,DBN1,SGSM2,TMCC2,SLC12A6,GNE,PLEKHO1,GAB1,SOWAHA,PIK3AP1,NFIA,GPR137C,GPSM2,FTO,SLC22A23,NUDT11,PEX26,KDM4B,SPATA7,DIP2A,SLC37A2,DDHD2,TRIM2,TMEM121,STXBP4" Coexpression 14767473-SuppTable2 Human Pancreas_Nakamura04_346genes GeneSigDB 4.08E-03 1.00E+00 2.79E-02 2.77E-01 63 294 "DGCR6,ADORA1,PLA2G6,ARSE,CADPS,ZSCAN18,SLC4A4,MYOM1,CLDN10,CLU,CRYM,SPOCK2,PITPNC1,SGSM2,CCDC3,FRY,RCAN2,RRAGB,F5,DLC1,EVL,TPPP3,NEURL4,BRPF3,ZNF559,GATM,GRB10,MUM1,ZNF385B,KCNJ16,LAMP2,PIK3AP1,MEF2C,MEIS2,ZNF862,NPR2,NRCAM,PBX1,PPARA,VSTM2L,PRPSAP2,ROGDI,WLS,SAFB,SOX6,ASRGL1,SGK1,NLGN1,SCMH1,GKAP1,SMARCD3,SNRPN,TNIK,SPP1,ARHGEF9,SEMA4A,ZFP90,AMOT,SLAIN1,ZBTB16,DNALI1,SEMA3B,WNK2" Coexpression M14447 Genes rapidly up-regulated in breast cancer cell cultures by estradiol [PubChem=5757]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.11E-03 1.00E+00 2.80E-02 2.79E-01 18 61 "ADD3,CA12,SCARB1,LARGE1,LRIG1,GREB1,EGR3,OLFM1,TUBB2B,MAP2,MAPT,APTX,ELOVL2,RBBP8,RXRA,IL17RB,SYBU,KAZN" Coexpression 16457687-GeneList Human Breast_Wilson05_76genes_her2 GeneSigDB 4.11E-03 1.00E+00 2.80E-02 2.79E-01 18 61 "PDXK,SCARB1,ADGRG1,FAM189A2,TJP2,PDE4DIP,RASGRP1,ARMCX1,HBS1L,KLHL23,KLC1,NAP1L2,PFKFB3,NKAIN1,LARP4,CADM1,WIPF1,ADAMTSL3" Coexpression M8673 Genes down-regulated in mice with skin specific knockout of TP53 [GeneID=7157]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.13E-03 1.00E+00 2.82E-02 2.80E-01 116 593 "TMCC3,SNX30,TAOK1,MRTFA,ANK3,LGR5,IGDCC4,RASL11B,DDX3Y,ATM,ATP2A2,BACH1,FUBP1,DDR1,CAMK2B,CANX,ARHGEF25,NEURL1,ADGRG1,CLCN3,CLU,TJP2,QKI,COL9A3,CRYM,TENM4,CSF1R,CX3CR1,MAML1,DCT,DLX1,DMD,EDN3,EFNA3,EGFR,ELN,SRRM1,PRMT5,SCARA3,ATP5PD,AFF2,CAMKK2,CELF1,ZMYND11,GALR1,USP19,TXNL4A,TNRC6A,OS9,GRK4,CACFD1,KAT7,AP4S1,BACH2,HNF4G,FAAP20,SMAD1,MAP4,MBP,MEIS2,MYH3,MYH6,NDUFA5,NFIA,NPY,NUMA1,GLIPR1L2,PAX6,PDE3A,TMOD2,PFKFB3,PKD1,PLEC,PLXNB3,FA2H,POLG,MASP1,PTPN13,PTPRE,RBBP6,RBBP8,ZDHHC14,MYH14,BAALC,RYR1,SCMH1,SMARCA4,INTS9,SNCA,SON,SOX2,SOX5,ERC1,UNC5B,NCDN,RHBDL3,PLCB1,ATP11A,WWC1,TRIM2,FRYL,HHIP,SLC44A1,THRA,TNNT1,RBFOX2,TRH,TRO,SSBP2,UBC,UBE3A,WRN,CELF4,PMEPA1,NAV2,NHSL1" Coexpression 15297395-SuppTable1 Human Lymphoma_Sriuranpong04_670genes_Epithelium(N)Metaplastic/DisplasticLesions(R)Carcinoma(T) GeneSigDB 4.14E-03 1.00E+00 2.82E-02 2.80E-01 92 456 "AXIN2,BRAP,NME5,KIAA1324,OSBPL6,ALCAM,AMPD2,OGT,EP400,UPRT,DDO,CDK10,ARHGDIA,PDE8B,RIPK1,RAB29,CAPN3,CAST,CLDN10,NPIPA1,MS4A7,RAB28,CLTC,FBXO7,ABCG2,CP,PLCH2,PYGO1,C2CD2L,ZC3H11A,ARNT2,DMTF1,ARRDC4,TOM1,EEF1D,EIF4G1,EIF4G2,BSCL2,EML1,ENO2,LRRC23,EPS8,ETV1,EZH1,TUBB4A,FCGRT,TMEM164,FHL1,GALC,GHR,C1QL1,BRD8,KIAA1958,HSPA1L,MSL1,KLC1,STMN1,LMO2,ADAM11,POC1B,MITF,NDUFA5,NUCB2,OXTR,PKD1,PKM,PRKCZ,KLK6,PTPRZ1,PEX5,RIC8B,YY1AP1,RPL38,ATXN1,SLC22A4,TET1,SMARCD3,RBM26,SYN1,COBL,TRIM2,DOCK9,TGFBR3,ZFP91,TMPO,TP53BP1,TPM4,NEIL2,VSNL1,ZBTB14,DNALI1,HNRNPA3" Coexpression M2635 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable ERBB2 [Gene ID=2064]. MSigDB C6: Oncogenic Signatures (v6.0) 4.15E-03 1.00E+00 2.83E-02 2.81E-01 45 197 "RALGAPA1,ADD3,MAP4K3,ASCL1,ZBTB10,MPDZ,CALB2,PTBP2,COL9A3,LRIG1,GREB1,RASGRP1,MBNL2,EGR3,KCTD3,ARMCX1,DLC1,FKTN,USP16,GFRA1,DBF4,GPER1,JAK2,KIF5C,MATN2,NRCAM,FAM216A,C1orf109,RBBP8,ERI2,RPRD1A,RMI1,HSPA4L,ZNF430,PEG10,ITPRID2,SS18,KANK1,ANKRD12,MTCL1,EHBP1,TIAM1,ACTR6,HIRA,WIPF1" Coexpression M4164 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the untreated cells at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 4.15E-03 1.00E+00 2.83E-02 2.81E-01 45 197 "GPRASP2,BIN1,ARRB2,LINC00173,ST3GAL5,TPP1,NMT2,TJP2,TBC1D5,SRGAP3,AK5,CPEB2,MBNL2,KCTD3,TENM1,PTK2B,GTF2IRD2,GABBR1,PRDM5,PTPRT,IL11RA,ITGAM,LYRM9,PCSK5,PDE4D,ENPP2,RETREG1,PPP3CC,SUSD4,ROGDI,RFX3,FNIP1,HKDC1,CHD9,GKAP1,RAP1GAP2,GSE1,AGTPBP1,NEU4,FAM200B,ZNF34,AKTIP,KAT6B,PIK3R5,TPM2" Coexpression M0 Genes down-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.20E-03 1.00E+00 2.86E-02 2.84E-01 36 150 "ACTN2,PPFIA2,BCAS1,DST,CACNA1E,KALRN,CDC42,DLGAP1,FAM169A,RUBCN,RIPOR2,SIRPA,RABGAP1L,MRNIP,USPL1,OLIG2,LRRC17,SUCO,CHL1,GRM5,ITPKA,KCNF1,VWA5A,NFYA,NOVA1,OPHN1,PRKAB2,SLC6A15,RGS3,TROVE2,ST5,TJP1,TNFRSF1B,VAV1,ZNF142,LRP8" Coexpression 16473350-Table1 Human Brain_Jrgensen05_59genes GeneSigDB 4.22E-03 1.00E+00 2.87E-02 2.85E-01 16 52 "BCL2L2,CALB1,CBLN1,MYRIP,RCAN2,EPHA5,ERBB4,GABRB1,GRM8,IGF1,CLDN11,RET,PAQR6,SNCA,TRIM9,SLC17A6" Coexpression 17573669-SuppTable1 Human Lymphoma_Jaye07_genes GeneSigDB 4.22E-03 1.00E+00 2.87E-02 2.85E-01 22 80 "CDK13,BCL7A,BMP7,CAMK2D,TMEM184B,CNR1,USP6NL,DAPK1,DMTF1,E2F5,AFF2,GPM6B,NR3C1,BACH2,MIER3,KIFC3,ZNF827,PXK,FNBP1,COLGALT2,SYPL1,UCHL1" Coexpression M8251 Genes up-regulated in B lymphocytes: control versus stimulated by anti-IgM for 3h. MSigDB C7: Immunologic Signatures (v6.0) 4.27E-03 1.00E+00 2.90E-02 2.88E-01 44 192 "CPNE2,AXIN2,SNX30,PLA2G4C,STK33,CLU,TCEAL2,NCAN,USP6NL,RASSF2,FCGRT,SPECC1,DKK3,GABRB1,GPER1,IL6R,IL12A,KCNN3,NELL2,PDE4B,PIK3R1,ATG16L1,RASGRF2,KLHDC8A,RYR1,ATXN2,FAM102A,ST8SIA1,BTBD3,RAB3GAP1,SOX1,CLUAP1,BEX1,C11orf87,TAB2,CEP68,UNC5D,TCF7,ZEB1,FBXL16,RGMB,SF1,MICU3,PRDM8" Coexpression M7538 Genes down-regulated in double positive thymocytes with ELK1 [GeneID=2002] knockout: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v6.0) 4.27E-03 1.00E+00 2.90E-02 2.88E-01 44 192 "N4BP2L1,CACNA1D,CASC2,STOML1,DGCR9,TJP2,HECTD1,WHRN,USP6NL,DNAJB6,SRRM1,PPP1R1B,C1orf61,LINC00654,CSPG5,ZNF546,GAREM2,DPP10-AS1,BCO1,NNAT,OCRL,PIK3CD,SNX10,TRHDE,MAPKAP1,EML5,PID1,IQSEC3,RNASE1,FOXRED2,TRA2B,EFHD1,SNCB,MYT1L,CLUAP1,SEPT8,EHBP1,PCDHGA1,PHF24,PLEKHH2,MTCH1,VSNL1,HRASLS,HNRNPA3" Coexpression 17683608-TableS3 Mouse StemCell_Ulloa-Montoya07_800genes GeneSigDB 4.30E-03 1.00E+00 2.92E-02 2.90E-01 133 692 "ADCY6,PCDH19,APBB2,APP,ASPH,CHID1,ADAM15,SEC11C,SYNJ1,SGCE,CAMK2D,FMNL3,LRRFIP1,LARGE1,CFL2,TPP1,CLTB,LETMD1,MAGED1,IFFO1,C2CD2,ENTPD4,CSF1R,FEZ2,ARHGEF10,MICAL2,VCAN,SOCS5,CST3,TCAF1,CTIF,DCTN1,C2CD2L,RHOBTB1,CD99L2,CPEB2,PDCD6IP,EDN1,SH3GLB1,MBNL2,STX2,VPS26C,EXTL2,FAM198B,TAOK3,FECH,AMOTL2,POLK,FOXF2,PCYOX1,FLNC,TMEM175,UFM1,STAMBP,SARAF,GAA,ZMYND11,NEK6,ARFIP1,RAB30,GLS,MSL3,OS9,GOLGB1,GSN,GSTM5,RASSF8,ICA1,ITGAV,JAK2,METTL21A,KIFC3,STXBP5,LIFR,MAN2A2,MEIS1,MEIS2,MKLN1,AFF1,MYO6,NUCB2,ETFRF1,PIK3R1,RETREG1,PMP22,LRP12,SLC36A4,MINDY2,PPP2R5C,PXK,RIPOR1,MORC4,CCDC82,TMLHE,ALG9,ROM1,ATXN7,CPEB3,ARHGEF40,SLC12A4,ARFGAP1,LMBRD1,GLT8D1,DBNDD2,SPART,ITPRID2,ST5,RGL1,DIP2A,ALG1,TBX15,SATB2,SYNE1,OBSL1,TGFBR3,SLC44A1,ZFP91,TPM3,TPM4,TUBB2A,UBE2H,AMOT,TOM1L2,NDRG4,SLC30A4,PMEPA1,ZXDA,NT5M,RNF103,MVB12B,ST7,KLHDC1,SENP7" Coexpression 19841744-TableS5 Human Liver_Tzur09_1908genes GeneSigDB 4.30E-03 1.00E+00 2.92E-02 2.90E-01 269 1499 "ACHE,ACLY,ABHD6,ARID1A,NDRG3,NDRG2,ADD1,ADD3,AP2A1,MTUS1,TXNDC16,AK2,ALAD,OGT,MAP4K3,PKP4,ANXA7,PARG,APC,UPRT,API5,CDC14B,MIER1,ARHGAP5,ASPH,ATM,STX16,ATP2A2,N4BP2L1,ATP6V0A1,BACH1,CFLAR,FUBP1,AP1M1,SGCE,NIPA1,BTRC,CALM1,CANX,CAST,SPAG9,REPS2,CDC27,CDC42,CFL2,MS4A7,CNOT8,KMT2C,CLCN3,CLU,FBXO7,QKI,HECTD1,NIPBL,ARMC8,RCHY1,CPS1,PNKD,CREM,CRHBP,NCOR1,CSF3R,DZIP3,SDC3,PNPLA8,CTH,CYBB,FGFR1OP2,TCAF1,TM9SF4,MATR3,DBT,FBXL5,BLOC1S6,RABGAP1L,TMCC2,MED12,CASP8AP2,ABI1,PDCD6IP,DNAJB6,E2F5,SH3GLB1,FAM13A,PHF20L1,APH1A,GOLGA7,KCTD3,EIF5,DCTN4,DMTN,GPHN,SRRM1,DENND4A,ACSL4,ST3GAL6,FDFT1,PRMT5,SEC23B,VTI1B,SYNCRIP,FOXO3,FOLH1,SPECC1,USP16,PDLIM5,USP21,ZNF512,OGA,STAG2,GAB1,HBS1L,GART,GATM,TUBGCP4,LYVE1,GK,COPS8,TNRC6A,GLUL,FERMT2,NUDT21,EML4,NR3C1,PSIP1,MAP4K5,ZHX1,MIER3,VSIG4,GABARAPL2,HMGCR,HNRNPK,IL6ST,TUBB2B,JAK1,JAK2,KLHL23,KIF2A,KIT,IPO5,LAMP2,LIFR,PAXBP1,MAT2A,MBNL1,MDM4,KCTD6,MKLN1,MRPL42,MXI1,NFIA,NFE2L2,NFYA,SLC11A2,NUCB1,ODF2,ZNF827,PAH,PCMT1,ENPP2,PIK3C2A,ANLN,PIK3R1,ZFYVE21,XRN1,GPSM2,PLXNB1,PRIMPOL,MAPKAP1,STRN3,RC3H2,PSAT1,EPB41L4B,DRAM2,PPARA,MED1,PPP2R5C,PROX1,MASP1,PTK2,PXK,ZSCAN32,OCIAD1,PEX2,TUG1,RAD17,RAP1GDS1,RDX,PBRM1,RPRD1A,PCMTD2,RPE,CLIP1,AP1AR,SAFB,SCP2,FNIP1,SFPQ,SUPT20H,TRA2B,COPZ1,ITSN1,MAGI3,FNDC3A,ST6GAL1,SLC6A9,MTERF2,CPEB4,SMARCA4,TTC17,SNCA,LMBRD1,MYCBP2,PEG10,KIF1B,CDK19,SPART,SRPK2,TAB2,PBLD,CLASP2,ITPRID2,MESP1,SS18,ERBIN,STAU1,GANAB,GSE1,NSFL1C,KLHL7,VPS13A,SYPL1,ANKRD28,ANKRD12,TAF9,TBCEL,TBL1X,ACSL6,TCF7L2,WASHC4,PUM2,FRYL,HIF3A,SIK3,DICER1,TMEM9,TMPO,BEX4,TPD52,NPL,TRPC1,TSN,SSBP2,TUBB1,UBE2H,OSBP2,VSNL1,NSD2,CLDND1,RICTOR,XRCC4,ZNF711,SH3GLB2,SMARCAD1,WNK1,WIPF2,WNK3,JMJD1C,RSPRY1" Coexpression M18559 Genes up-rgulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 6h. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.35E-03 1.00E+00 2.95E-02 2.93E-01 23 85 "CA8,PDE4DIP,TOX,EDN1,LPAR6,PCOLCE2,CALCRL,FAM198B,PCDH17,OLFM3,PCDH9,SERPINI1,PLCL1,PTPN13,FIGN,SLC25A36,SCN2A,SYBU,LIMCH1,DMXL2,TEX15,P2RY12,FRMD6" Coexpression 15665281-TableS1 Human Brain_Wong05_89genes GeneSigDB 4.39E-03 1.00E+00 2.97E-02 2.95E-01 19 66 "BCAS1,CALB1,CHGB,LHX2,COL9A1,PPP1R16B,EGR3,NCALD,TUBB4A,GPR17,MBP,NPTX2,CDK18,PLP1,FA2H,FERMT1,MYT1L,SPP1,TRH" Coexpression M8622 "Genes down-regulated in bone marrow-derived dendritic cells treated by CSF2 [GeneID=1437] and 1,3-beta-D-oligoglucan [PubChem=11375554]: low dose versus high dose." MSigDB C7: Immunologic Signatures (v6.0) 4.40E-03 1.00E+00 2.98E-02 2.96E-01 43 187 "ADRA1B,ANK1,DST,CHN1,CNGA3,PDE4DIP,MYADM,KATNAL2,SCRN1,ETV1,SIRPB1,FERMT2,TDRKH,BVES,FAM107A,PADI2,HLF,ICA1,KIF5C,LIMS1,MDFI,TM6SF1,WDR49,PPP2R2B,MAPK10,LRRC49,PXK,PTPN13,ZFHX4,RORB,KIAA0895L,SATB1,SH3GL2,SLC12A2,MTERF2,SOX5,ANO4,TMEM9,RGMB,VLDLR,WNT7A,PLSCR4,SLC4A10" Coexpression M365 Genes up-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-03 1.00E+00 2.98E-02 2.96E-01 39 166 "HACE1,PDZD4,USP28,MADD,ARNTL,DPY19L3,CFLAR,SCAPER,CDC42,GIT2,FBXO25,PDCD6IP,SIDT2,MBNL2,KMT5B,PLEKHA1,EZH1,PDLIM5,ERGIC3,FAM120B,RAPGEF6,SYNPO,MBNL1,P2RX7,PDE3B,MINDY2,PPP2R5E,PRKACB,PTPRE,CEP97,RFX3,SUPT20H,FAM102A,CHD9,TNIK,WBP2,RNF103,PARP11,ZDHHC20" Coexpression M8893 Genes up-regulated in pro-B cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.41E-03 1.00E+00 2.98E-02 2.96E-01 39 166 "PKP4,BMP7,ENTPD4,CRY2,PHF14,ARHGEF4,RIPOR2,KLHL3,TSPAN5,PLEKHA1,CHST15,FGF13,AHDC1,B4GALNT4,ADAMTS6,AGBL5,SCIN,KCNA2,SMAD1,SESN3,NEFH,NF1,SLC11A2,P2RX7,CEP41,SIDT1,TTC13,SEC61A2,KCNIP2,SEMA6D,SH3GL3,DZIP1,SEMA4A,TCF4,TCF7,ARHGAP9,TGFBR3,SSBP2,PRDM2" Coexpression M17083 "Up-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the mature B" MSigDB C2: CGP Curated Gene Sets (v6.0) 4.44E-03 1.00E+00 3.00E-02 2.98E-01 24 90 "DGCR6,ADD1,ADRB2,TBC1D14,LY86,SLC4A7,RIPOR2,YTHDC1,EBI3,B4GALNT1,IRF8,JAK2,MEF2C,POU6F1,PXK,RAP1GDS1,RMI1,SELL,RASA3,SH3BP2,FAM102A,MYCBP2,LAT2,PHTF2" Coexpression M9126 Genes up-regulated in cancer stem cells derived from glyoblastoma tumors: CD133+ [GeneID=8842] vs. CD133- cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.47E-03 1.00E+00 3.01E-02 2.99E-01 13 39 "SLITRK1,PROM1,SOCS6,AKAP7,COL9A3,RTTN,FGFR3,SALL3,NELL2,RLBP1,OBSL1,C18orf54,LAMP5" Coexpression M347 Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE and H2O2 [PubChem=5283344;784]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.47E-03 1.00E+00 3.01E-02 2.99E-01 13 39 "APC,ARHGDIA,CCNT1,CDH2,ERBB2,FECH,FGFR1,ITGA7,DDR2,PDYN,SYP,TJP1,TSC2" Coexpression M2300 Genes down-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout compared to normal 9.5 dpc embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.47E-03 1.00E+00 3.01E-02 2.99E-01 13 39 "PCDH19,IGDCC3,CP,FEZ1,EN2,TUBB3,SPSB4,DLL3,SCG3,NNAT,TUBB2A,UCHL1,TRIM9" Coexpression 16715129-SuppTable4 Human HeadandNeck_Jarvinen06_502genes GeneSigDB 4.50E-03 1.00E+00 3.04E-02 3.02E-01 90 446 "DSCAML1,KLRC4,CDC7,BEGAIN,EP400,APC,AQP6,DDX3Y,ATP1A1,MTMR9,SEC11C,MTMR2,SGCE,BSN,CBR1,CCNH,CCNT1,CDC25B,CLGN,CACNA2D2,PLEKHB1,CLTA,IFFO1,CRHBP,CST3,TCAF1,MYEF2,COPS7A,DDX46,ATN1,RCAN1,ST8SIA3,FSD1L,MBNL2,EIF5,RCAN2,FECH,SEC23B,AP4B1,GABRG2,ACSS1,USP19,TXNL4A,OS9,NR3C1,TMEM25,LINGO1,PSIP1,NCKAP1L,SCRG1,AGFG1,LRRCC1,IL6ST,IL11RA,ITIH2,LRP1B,MID1,MMP17,NACA,FXYD6,NDUFA5,OMG,ZFYVE21,JAKMIP1,POU6F1,MAPK10,QRICH1,SPDL1,TRIM68,REV3L,ERI2,SUPT20H,SHMT2,SLC1A6,DHX30,SLC12A2,SLCO1A2,LMO3,CLASP2,ZNF302,NEK4,PCDHB15,PCDHB10,HHIP,TPM2,TRIO,GORASP1,MFF,PRTFDC1,NAV2" Coexpression 20490655-ST3 Human Breast_Sabatier10_368genes GeneSigDB 4.51E-03 1.00E+00 3.04E-02 3.02E-01 72 345 "ACTN1,ADORA2A,KIDINS220,ANXA7,CACHD1,DACT3,NCOA1,CBS,CD38,CD81,PNKD,C2CD2,CTNND2,CX3CR1,ECE2,BOC,PHF19,CNIH3,RCAN1,E2F5,EDNRA,ATL1,EFNA3,PCOLCE2,EPB41,ERBB4,SPEG,EXTL2,KATNAL1,MRVI1,DLC1,ATP8A1,PPP1R1B,FHL1,IQCG,FOXM1,FLNC,GABBR1,ERAP1,COPS8,FERMT2,SLC2A6,GYG1,LAMA2,MDFI,MYO7A,NPR2,DDR2,PCDH18,CEP41,MAPK7,PTPRZ1,RFX5,RGS4,MCMBP,MAGI3,SLC4A3,SMTN,LIMS2,ZCCHC24,MPRIP,DNAJC9,OBSL1,THBS4,TNFRSF1B,TPM2,TTC3,CADM1,VSNL1,NAV3,RTN4,MSRB3" Coexpression 16143142-Table3 Human Colon_diPietro05_100genes GeneSigDB 4.51E-03 1.00E+00 3.04E-02 3.02E-01 25 95 "C1QTNF3,LGR5,ARSE,STX16,CDC42,ADGRG1,TM9SF4,CELSR3,EPB41L1,FCGR1A,GABBR1,GALC,GJB1,GLS,GNG4,VSIG4,INPP1,KCNK1,SATB1,ST6GAL1,SPP1,PLCB1,TCF7,ZMYND8,GDPD5" Coexpression 18559498-SuppTable1 Mouse StemCell_Peinado08_184genes GeneSigDB 4.51E-03 1.00E+00 3.04E-02 3.02E-01 25 95 "MARCH3,RAB29,IL33,CDC25B,ABCG2,CRYBB1,ARMCX2,RPS6KL1,TMTC1,BSCL2,ATP13A4,CGREF1,NCKAP1,TLX1,LRRCC1,KLHL23,LMO1,ASPRV1,CD200,SAMD14,LRRC49,CCDC92,FCHO1,RGL1,PDSS2" Coexpression 18440302-SuppTable1 Human Lung_Ma08_378genes GeneSigDB 4.51E-03 1.00E+00 3.04E-02 3.02E-01 56 257 "ADD3,MTMR9,BCHE,CACNA2D1,NFS1,ACBD5,CNRIP1,CLOCK,PREPL,RUBCN,TCAF1,LONRF1,DNAL1,DTNA,E2F5,FAM13A,ABI2,PLEKHA1,VPS13B,SCML2,SEC23B,VTI1B,ANKFY1,CELF1,MSANTD4,GCNT2,NR3C1,ARHGAP19,HMGCL,HMGCR,DHX35,KPNA5,MAP2,CHIC1,OCRL,ZNF827,PTCH1,TRIM68,FIGN,RFX5,ZDHHC4,FBXW7,KIF21A,PPM1E,KANSL3,RCOR3,PEG10,BEX1,CDK19,TBCEL,TBL1X,TGFBR3,KCTD2,RBFOX2,TPD52,TSC1" Coexpression M17387 Genes down-regulated in MFCF-7 cells (breast cancer) by exogenous HG1 [GeneID=2688]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.55E-03 1.00E+00 3.06E-02 3.04E-01 30 120 "FAM135A,KCNAB2,ARSF,USP2,SLC4A7,CPS1,GALNT9,SNAP91,ELAVL4,MED12L,GAD2,GBX2,DBF4,CBX1,MITF,PFKFB4,PIK3C2A,PURG,MINDY2,PYGM,RASGRF2,ZFP2,SGK1,SOX1,SP4,NACAD,APOM,SYNPO2,UBE3A,ZNF19" Coexpression 19261849-TableS4b Human Endometrial_Salvesen09_13genes GeneSigDB 4.56E-03 1.00E+00 3.06E-02 3.04E-01 3 3 "KALRN,CHD5,FBXW7" Coexpression M11028 Genes in the most frequently gained loci in a panel of glioma cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.56E-03 1.00E+00 3.06E-02 3.04E-01 26 100 "DPF1,SYT13,DGKZ,APOC1,APOC2,MADD,MARK4,DGKI,CHRM4,KMT2C,CRY2,GALNT9,ELMO1,ERCC2,PRKAG2,FOLH1,CLASRP,ZBTB45,PCDH18,RELN,PTPRN2,GALNT10,NLGN1,SMARCD3,SYPL1,VIPR2" Coexpression M8135 Genes up-regulated in cytotoxic T cells: control versus treated with Akt inhibitor VIII [PubChem=10196499]. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "MTUS1,ANK3,PPFIA3,AQP4,CACNA1A,DCLK1,B4GALT6,MAP4K4,ERC2,ARHGEF4,EBI3,EGR3,ERBB4,GAD2,MYOZ2,GLI2,GPM6A,PCLO,IDH3A,IL12A,KPNA5,LIMS1,MOBP,NAP1L3,NF1,SLC11A2,OPCML,RETREG1,PRKAB2,MAPK8,MASP1,SCN2A,SH3BP2,CHD9,ANKRD6,ZNF365,RPH3A,SLC6A9,SOX15,IDI2-AS1,ZC3H13,CEP68,PCDHGA10,AP4E1,PMEPA1" Coexpression M7610 Genes down-regulated in memory CD8 T cells: 1' versus 4'. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "ADD3,ALAD,ARNTL,BACH1,ZBED5,TPP1,ARMC8,LETMD1,ENTPD4,NCOR1,RUBCN,GPRASP1,RIPOR2,DCAF8,ZFYVE16,FBXL5,ZC3H11A,ABI1,RASGRP1,TNK2,USPL1,PLEKHO1,VPS13B,HPCAL4,SARAF,STAG2,ZNF862,RC3H2,PRKCZ,SAMD9,SNRK,DPF2,FAM192A,CHD9,ST6GAL1,TTC17,SON,SPTAN1,RBM26,ZNF302,ERBIN,AGTPBP1,DOCK9,DICER1,WIPF2" Coexpression M8034 Genes down-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "ADCY8,ADRA1B,APBB1,CASK,ARNTL,MARCH3,ARHGEF7,ARHGEF1,CBFA2T2,ENTPD6,CDR1,CLCN4,GPRASP1,ZNF337,SPOCK2,KIAA0753,ABCC5,TENM1,ING4,PTK2B,AKAP3,GABRB3,INPP5K,STON1,PTGDR2,KLF12,RETREG1,PLXNB1,FSD1,PRKCG,GRAMD1C,STK32B,MAP6D1,SATB1,SCN8A,SH3GL3,HKDC1,SLA,ARFGAP1,KIF21B,KDM4C,ACSBG1,RUSC1,PLPPR2,MPPE1" Coexpression M5448 Genes down-regulated in comparison of mast cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "DPF1,ACHE,CLK4,ADD3,CASK,ARHGAP5,ATP1A1,NRXN1,NECTIN3,ARHGAP24,ARMCX2,DLG3,EGFR,SORBS3,IRAK4,EIF1,EZH1,FHL1,RAPGEF6,SEPT9,DIDO1,HRH3,JAK1,KIF2A,MBP,PALM,POLG,ZCWPW1,ZNF493,MCMBP,AP1AR,SATB1,SBF1,SCN3A,SH3BGR,FRMPD1,ARFGAP1,CLUAP1,KIF1B,ELOVL4,CAMTA1,TCF7,PSD3,MPPE1,IFT88" Coexpression M5341 Genes up-regulated in comparison of control polymorphonuclear leukocytes (PMN) at 0 h versus PMN treated with F. tularensis vaccine at 3 h. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "ADAR,ADD1,OSBPL8,APAF1,CAPRIN2,CAMK2G,NFS1,RCBTB2,BAG4,FEZ2,IPCEF1,COPS7A,C2CD2L,DDX46,RABGAP1L,PDCD6IP,FRY,EPB41,CEP85L,STRADA,NPTN,FYB1,GAB1,JAK2,GPR155,NASP,NRDC,TATDN3,GRAMD1C,CYBC1,DEF8,OXR1,RMI1,R3HDM2,SMARCC2,TMCC1,FAM219A,NSFL1C,ARHGAP9,FAM200B,TSC1,TST,XPO1,MPPE1,UBE3B" Coexpression M8226 Genes up-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype untreated versus RORC [GeneID=6097] knockout treated by digoxin [PubChem=2724385]. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "ARNTL,ARHGEF7,TRIM41,PRC1,AIFM1,CD38,ARHGAP33,WHRN,EPB41L2,MTSS1L,RCSD1,KATNAL1,TUBB3,FECH,FGFR3,PTGDR2,FRMD3,MIER3,KCNA2,LSS,ANLN,PURG,SNRK,UHRF1BP1,GAL3ST4,ERI2,RIC8B,DCUN1D2,STK32B,SMPD3,HKDC1,SLC12A4,GKAP1,TMCC1,ZC4H2,ELOVL4,SYNE2,DNMBP,TCF12,C18orf54,KAT6B,USP1,ZNF709,NSD2,TTC7A" Coexpression M5492 Genes down-regulated in comparison of macrophages versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "APAF1,STX16,AZGP1,BACH1,SLC25A14,ARHGEF1,LRRFIP1,NDST3,CX3CR1,SV2A,ABCC5,EEF1D,PLXNC1,EYA1,FOXO3,ZNF44,GRIA2,BTN2A1,KAT7,LSAMP,MARK3,GPR88,SAMD9,PTAFR,PTPRG,ARID4A,SCN2B,SEC14L1,GALNT10,PPM1E,SLC6A11,MYO16,SOX10,UHRF1BP1L,UNC5B,MAPK8IP3,SYNE2,ANKRD12,PDLIM2,AGTPBP1,PUM2,DICER1,CABIN1,ZMYND8,NLRP3" Coexpression 18316601-Table1 Human Breast_Rizki08_204genes GeneSigDB 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "ASGR1,ATP2A2,C5,CACNA2D1,P2RX6,CD81,DCLK1,COPB2,TAOK2,NRXN3,CSF3R,MED12,HIPK3,PLXNC1,SRRM1,CDKL3,SEC24B,FGFR1,FYB1,GPR19,GRIN1,GRM3,GUCY1A1,KCNA4,MATK,MEF2C,NEK1,PDYN,ABCB1,PSD,PTAFR,ARID4A,RFX3,SGK1,SLC12A4,SLC14A1,SLC20A2,SMARCE1,SPTAN1,USP22,TGFBR3,LILRA4,KCNE5,SSBP2,FXR1" Coexpression M7701 Genes down-regulated in CD4 [GeneID=920] T cells: control versus tretinoin [PubChem=444795]. MSigDB C7: Immunologic Signatures (v6.0) 4.58E-03 1.00E+00 3.06E-02 3.04E-01 45 198 "DPF1,SEMA6A,BCAR3,SHROOM2,ATP2A2,RHBDL1,USP2,CLTC,WHRN,HAPLN1,RUBCN,YTHDC1,RUSC2,SEC16A,MAMLD1,HIPK3,EFNA2,SORBS3,RGS17,COQ7,SEC23B,FOLR2,DOT1L,GSN,ITGAM,MX1,MYO6,MYT1,PAH,PFKFB3,RC3H2,SNRK,PSMD13,SLC8A2,RAB3GAP1,NPAS3,APOM,CHST8,ZMAT3,TGFBR3,DNAJC12,MTCH1,FTSJ1,TUBA1A,ITM2C" Coexpression 18849563-SuppTable5a Human Lung_not_cancer_Bhattacharya09_84genes_COPDvsControl GeneSigDB 4.62E-03 1.00E+00 3.09E-02 3.07E-01 20 71 "ABHD6,LTBP4,APBB2,RUNX1T1,QKI,DLC1,ZNF44,KIT,MYT1,PPP3CC,PTCH1,RBBP6,SH3GL3,ANKRD6,SEPHS1,ZNF302,ARHGEF12,UBTF,ZNF177,ZNF248" Coexpression 17699775-SuppTable2 Human Lung_Johnson07_571genes GeneSigDB 4.65E-03 1.00E+00 3.11E-02 3.09E-01 83 407 "ARID1A,FMNL2,INTS2,MTUS1,ALCAM,MARCH4,LTBP4,SYT13,CAPRIN2,DDX3Y,DOCK11,ADGRB2,OSGIN2,SYNGR3,NGEF,TJP2,QKI,COL4A5,BTF3L4,CNRIP1,FAM171B,GDA,CSF2RA,MICAL2,ECE2,PHF19,RASSF2,PITPNC1,AK5,DOCK2,GOLT1B,E2F5,EDIL3,TSPAN5,HIPK3,FCF1,STARD3NL,F5,OLFM1,FHL1,SCARA3,DPYSL4,CSPG5,GALC,DNER,GATM,DBF4,TNRC6A,GLUL,HLF,IFI16,IGFBP1,KCNJ16,KCNK1,KCNMA1,L1CAM,LAMP2,ZNF680,NAP1L1,NAP1L3,NME4,SLC11A2,PDE3A,SERPINE2,NALCN,FIGN,LGR4,WLS,SLC22A4,DOCK9,OBSL1,NSD1,GPRIN3,DICER1,GPR161,SLC44A1,CBX5,PLEKHH2,CSDE1,NAV3,NHSL1,ZDHHC20,FRMD6" Coexpression 19116885-table3 Mouse Colon_Wang09_59genes GeneSigDB 4.69E-03 1.00E+00 3.13E-02 3.10E-01 15 48 "HACE1,CAMK2G,CDH2,TENM4,FEM1B,KCNH1,PIK3C2A,RGS12,RASA3,EFHD1,TNR,EIF4ENIF1,TBC1D15,PRDM2,CSDE1" Coexpression 17430594-tableS3 Human Prostate_Chandran07_307genes GeneSigDB 4.70E-03 1.00E+00 3.13E-02 3.11E-01 50 225 "LTBP4,GPRASP2,ANK3,BCAS1,AZGP1,SCAPER,CAMK2G,CCNT1,LRRFIP1,DNAJB5,CNN3,SLC4A7,NCOR1,TOMM20,ZC3H11A,G3BP2,EFNA3,MRPL10,NPTN,ERGIC3,AHCYL1,PRUNE2,MSL1,IDH3A,ITPKB,MAOB,MATN2,PHKG1,TNPO2,PPP2R5C,PPP3CA,CASTOR1,PTPRN2,ZDHHC4,SATB1,COPZ1,PAAF1,LIMS2,SLC12A4,SLC20A2,TTC17,SS18,KANK1,NSFL1C,JMJD6,TACC1,CAMTA1,TPM1,CAB39L,SSPN" Coexpression M2741 Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of SUZ12 [Gene ID=23512] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.72E-03 1.00E+00 3.15E-02 3.12E-01 44 193 "SYN3,ADCY2,SLC12A5,ANK1,ARRB2,MYOM1,KALRN,LDB2,USP2,DLGAP1,CACNA2D2,SRSF11,CHN2,SLC4A8,DCC,KBTBD11,DRP2,KCNMB2,CACNG2,ZIC4,KAT8,STAU2,RUNDC3A,GUCY1B1,HAPLN2,KLHL23,MAPT,MARK1,MEIS2,NPY,OPCML,FXYD1,SCHIP1,PTPRO,ATG16L1,RFX2,KLHL11,RAVER2,RPS6KA2,SLITRK3,NLGN1,BTBD7,TACR1,WRN" Coexpression M4224 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h versus the untreated cells at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 4.72E-03 1.00E+00 3.15E-02 3.12E-01 44 193 "ABHD6,ADORA1,USP35,ANK1,EPB41L5,ZFYVE28,NRP2,NIPA1,CA4,VXN,ASIC3,FAM19A5,CSF1,ADGRV1,DLC1,NEK6,FREM1,GGT7,PCDH11X,GPR12,LRRTM1,ZFYVE27,MAOB,MEST,IGSF11,PDE4A,LOC283856,MBOAT7,PKIA,SLC26A11,NCR3LG1,PTPRD,TMEM145,PRIMA1,RTN1,TMEM200C,IL17RB,SGK1,ZNF365,NFASC,ADHFE1,TIMP4,CSMD1,REEP1" Coexpression M8578 Genes up-regulated in Th17 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 4.78E-03 1.00E+00 3.18E-02 3.16E-01 40 172 "CPNE2,ADD1,BEND6,USP37,BMPR1B,CLGN,NMT2,DNAJB5,AKAP6,SLC4A8,EBF1,PIPOX,BAIAP2,EVL,EFCAB2,JKAMP,NCKAP1,GPM6A,MAP4K5,KLF12,IRF8,IGF1,BRINP3,LYPLAL1,NRCAM,ENPP2,HYDIN,PTPRG,KLHL11,ASRGL1,TRA2B,SGK1,MAGI3,MPRIP,STXBP1,SYNE2,ADGRL3,SATB2,TLR4,TPM4" Coexpression 15489886-TableS1b Human Sarcoma_Mason04_549genes GeneSigDB 4.79E-03 1.00E+00 3.19E-02 3.17E-01 93 464 "CDC7,ALCAM,LTBP4,APBA2,CDC14B,CDK10,SLC4A4,ATP2A2,BARD1,SYNJ2,GYG2,SGCE,PRC1,DGKI,CDC25B,CDH2,CRLF1,CLU,QKI,ARHGEF10,DZIP3,SDC3,RASSF2,SV2A,AK5,NR1D2,CASP8AP2,EDIL3,EDNRA,EDNRB,RBM12,RASA4,ELN,EPB41L2,EPS8,EFS,EFEMP1,FGF1,FGFR1,AMOTL2,SCARA3,FOXM1,FLNC,CHL1,GLI2,GLUL,PSIP1,ARHGAP19,HMGB1,IL11RA,KCNK2,KCNMA1,KIT,STMN1,MATN2,MATN3,MEIS1,NASP,NUCB2,PBX1,PDGFRA,ENPP2,GPSM2,PRRX1,LRRN3,RELN,PTN,ZNF532,RPS6KA2,SALL1,SFPQ,DOCK10,RUFY2,SNAP25,KIF13A,SOX11,DNAJC9,PLCB1,ANKRD28,TCF4,SYNE1,TEK,ZFPM2,ITGB3BP,GPR161,TMPO,TPM1,TRO,USP1,NSD2,XRCC4,SCG2,NETO2" Coexpression M2426 Genes translationally up-regulated in HUVEC cells (endothelium) grown on FN1 [GeneID=2335] compared to those grown on laminin 1. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.80E-03 1.00E+00 3.19E-02 3.17E-01 12 35 "ARHGDIA,STX16,HOMER3,DAPK3,DYRK1A,MMP16,PDE3A,PPP5C,SRPK2,SSTR2,TRIO,SH3GLB2" Coexpression M7409 Genes highly expressed in the neonatal hippocampus (clusters 4 and 8). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.80E-03 1.00E+00 3.19E-02 3.17E-01 12 35 "CDH2,MYEF2,FABP7,TUBB3,UBE2E3,CHL1,TUBB2B,L1CAM,NCAM1,USP22,TUBA1A,ST8SIA2" Coexpression M3001 Genes up-regulated in type 1 (soleus) vs type 2B (EDL) myofibers. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.80E-03 1.00E+00 3.19E-02 3.17E-01 12 35 "ACTN2,ATP2A2,FHL1,MYOZ2,PPARGC1A,MYH3,MYH6,MYH7,MYL3,PPARA,TNNT1,TPM2" Coexpression M422 Genes down-regulated in dendritic cells: immature versus mature inhibitory treated by prostaglandin E2 [PubChem=5280360]. MSigDB C7: Immunologic Signatures (v6.0) 4.90E-03 1.00E+00 3.25E-02 3.23E-01 34 141 "HFM1,UPRT,ARHGDIG,ASGR1,CARMIL3,RGS9,BLM,ZFYVE9,CTH,MYADM,KCTD8,TMCC2,DMPK,EGFR,RAB9B,EPS8,NCALD,AMOTL2,TPPP3,HIGD1B,C1QL4,ICA1,KIT,PACRG,MDM4,NEK1,HCN1,GNG2,CRLS1,MYO16,TSNAXIP1,SYNE2,VWCE,ZBTB16" Coexpression M8890 Genes up-regulated in multipotent progenitors versus common lymphoid progenitors. MSigDB C7: Immunologic Signatures (v6.0) 4.91E-03 1.00E+00 3.25E-02 3.23E-01 39 167 "NDRG3,ADD3,ATP6V0A1,GPR146,LDHD,FUBP1,ARHGEF1,FBXO7,ATRNL1,RIPOR2,RASSF2,DAPK1,RASGRP2,TLR7,PRKAG2,EVL,PDLIM5,TUBGCP4,JAK1,KCNH2,MOV10,PGAM2,PLCB2,PMS2,SLC26A11,PRPSAP2,RGS10,KCNIP2,RASA3,PPP1R9A,DZIP1,CLUAP1,CDK19,TSPYL2,CEP68,STX1A,CAMSAP2,SGK3,PARP11" Coexpression M8188 Genes down-regulated in double positive thymocytes: wildtype versus over-expressing HDAC7[GeneID=51564] fused with VP16. MSigDB C7: Immunologic Signatures (v6.0) 4.91E-03 1.00E+00 3.25E-02 3.23E-01 39 167 "ABR,BCAR3,SEMA7A,BCL7A,NRP2,BID,NAE1,CACNA1E,CD38,CD81,MS4A7,CDC42BPB,CYBB,SIRPA,FBXL5,SRGAP3,PLXNC1,LILRB4,LDLRAD3,PDE4D,SERPINE2,FTO,RASGEF1B,PRKACB,QDPR,ROGDI,ZMAT4,ATXN1,FOXRED1,DOCK10,MYCBP2,PDLIM2,ARHGEF12,CYB561A3,RUNDC3B,TRPM2,TRPS1,MICU3,PLD4" Coexpression 16115903-TableS1 Human Breast_Rouzier05_298genes_4classes GeneSigDB 4.97E-03 1.00E+00 3.29E-02 3.27E-01 60 280 "TTYH1,ABAT,KIAA1324,ALCAM,BBOX1,APBB2,PROM1,CA12,CLGN,CHI3L2,LRIG1,CST3,GREB1,FBXL5,MED24,EEF1A2,EGFR,KCTD3,ERBB2,ERBB4,FAM198B,ST3GAL6,FGFR3,UBE2E3,EVL,GABBR1,GFRA1,GLS,TOX3,GLUL,GPM6B,ELOVL5,IFI16,IL6ST,MAPT,MATN3,MID1,FXYD6,PBX1,PFKP,SERPINE2,RETREG1,ELOVL2,PTX3,SATB1,GALNT10,KIF16B,SYBU,SOX10,SOX11,DBNDD2,GSE1,SYT1,TRIM2,UCHL1,DNAJC12,NPDC1,REEP1,SH3GLB2,DNALI1" Coexpression 19962670-TableS2 Human Ovarian_Mok09_200Genes GeneSigDB 4.98E-03 1.00E+00 3.30E-02 3.28E-01 33 136 "ACLY,TMEM132B,BACH1,CA4,JAM2,CRYM,FGFR1OP2,GOLT1B,REEP2,DLC1,PHYHIPL,MEGF10,GGTA1P,KIAA1958,GPR22,ATE1,GUCY1A1,UBE2QL1,BACH2,KIAA1755,LAYN,NASP,NFYA,A2ML1,PKIA,SYTL2,PTPRD,TRA2B,ITSN1,SLC8A1,RELL2,NSD2,ZNF248" Coexpression M15491 Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.00E-03 1.00E+00 3.31E-02 3.29E-01 89 442 "APOC1,SHTN1,PDXK,ASPH,ATM,BCHE,CA12,CLDN10,SYNGR3,CCPG1,QKI,ARMC8,COL4A5,CSF2RA,RIMS2,PPP6R2,EDRF1,HDAC4,TOX,DNAJC6,ZNF804A,ARNT2,CHRDL1,DNAJB6,EEF1A2,ENO2,EPB41L1,DENND4A,F3,EFEMP1,ST3GAL6,CHST15,PRKAG2,FHL1,RGPD5,FLT1,CSPG5,FYN,GABRA2,WASF3,NR3C1,FICD,SLC2A6,PACSIN2,HMGCR,LSS,MAT2A,MATN2,MBP,MITF,MX1,NELL2,NINJ2,OGG1,PCDH9,PCSK5,PDE4B,PDE4D,PIK3CD,RETREG1,PMP22,RC3H2,VPS13C,PTPRE,RASGRF1,MCMBP,RPS6KA2,SBF1,ZNF430,SHANK2,LIMCH1,ZCCHC24,EPB41L3,STXBP1,CAMSAP2,TBL1X,KIAA0930,TCF7L2,TPCN2,WASHC4,ATP13A2,NACC2,KAT6B,TNS1,TPM1,TSC1,TST,VLDLR,SH3GLB2" Coexpression 19088021-supptable2 Human Colon_Jorissen08_829genes GeneSigDB 5.02E-03 1.00E+00 3.31E-02 3.29E-01 128 666 "KCNH8,AXIN2,SNX30,AK2,C1QTNF3,CEP126,APOC1,USP37,CDC14B,CADPS,ASPH,ZBTB10,STX16,C1QC,USP6,CBFA2T2,CD38,LRRFIP1,UBE2L6,SRSF11,SOCS6,CHN2,NIPBL,FAM149A,SLC25A27,RCHY1,ACBD5,MYRIP,CHD1L,MICAL2,FAM169A,DOCK4,KLHL3,DPH1,SEZ6L2,SUGP2,EGFR,EIF5,IRAK4,CDHR1,FCGR1A,PRMT5,POLR1B,JKAMP,TMEM107,CAMKK2,KHDRBS3,GAD1,ERAP1,MTHFD2,KIAA1841,KCNMB4,FUT10,PCLO,PSIP1,MUM1,HPS5,SMAP1,METTL21A,KLHL23,KLC1,CAMK2N2,PIK3AP1,CD200,BLOC1S2,PBX1,SERPINE2,RETREG1,GPSM2,PRIMPOL,STRN3,RC3H2,EPB41L4B,TATDN3,EPDR1,SYTL2,PTCH1,ANKHD1,OCIAD1,PTPRD,PTPRO,TUG1,CEP97,RBBP8,UBR7,CCDC25,PRR5L,RXRA,ATXN1,ATXN2,ATXN7,HSPA4L,FERMT1,SLC2A5,PPP4R3A,SHANK2,BTBD7,SLC20A2,SMARCC2,SMARCE1,TMCC1,EMC1,ZNF423,ATP10B,STAU1,CEP68,KAZN,ROBO3,DMXL2,SATB2,PCDHGC5,WDR7,PMS2CL,FBXL16,TIAM1,TPM4,STXBP4,NSD2,WRN,ZIC2,ZBTB38,PMEPA1,SLC38A1,NAV2,CAB39L,RTN4,VANGL2,NHSL1" Coexpression 17284527-TableS4 Human Lypmhoma_Leval07_241genes GeneSigDB 5.03E-03 1.00E+00 3.31E-02 3.29E-01 38 162 "ADD2,ADD3,ATM,FUBP1,TJP2,ARHGEF6,RBM39,IPCEF1,NR1D2,PHF20L1,CERCAM,COQ7,WAC,RPS6KC1,TBC1D16,ZSCAN30,FYN,PSIP1,KLF12,BACH2,KPNA5,MBD1,MBNL1,SESN3,PDPK1,GNG2,PPP2R5C,PRKACB,PRPH,USP47,FNIP1,SELL,KIF1B,LRRC4,SEPT8,CDH22,RICTOR,SLC38A1" Coexpression M8380 Genes up-regulated in CD4 [GeneID=920] T cells: TGFB1 [GeneID=7040] versus TGFB1 [GeneID=7040] and progesterone [PubChem=5994]. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "LTBP4,PPFIA4,KIF1A,BCL7A,RAB29,CACNG1,THSD7A,PICK1,CNTN1,PCYT1B,IPCEF1,VCAN,SPOCK2,EDNRB,SH3GLB1,TNK2,OLIG2,REEP2,PTK2B,AHDC1,GLS,LPAR4,GRIK2,ARHGAP19,IGF1,JAK2,VWA5A,NOS1,P2RX7,PCSK1,PDE3B,PRPH,WBP1L,RFX5,RORB,SLC11A1,SNAP25,PDZRN3,ZCCHC24,SPART,SYT11,KIAA1107,WWC1,PUM2,TMOD1" Coexpression M5322 Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells from young donors treated with TSST at 40 h versus those from old donors treated with TSST at 40 h. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "BCAR3,ATP2A2,BID,PLEKHB1,RAB33A,MAP4K4,HINFP,NCOR2,KIAA0408,HDAC4,ZNF337,DAPK1,FAM13A,EGR3,PLEKHA1,BSCL2,KIAA1109,VTI1B,ZNF274,ACOT7,MBD1,NAP1L2,ZFYVE21,PRKCZ,GRAMD1C,GON4L,ZSCAN32,RALGDS,YY1AP1,RPS20,SEC31A,INTS9,DOP1A,ZSWIM8,KANK1,VAMP1,ATP11A,SLC35G2,TGFBR3,TNFRSF1B,TPD52L2,SMUG1,MICAL1,ZNF189,TFIP11" Coexpression M5543 Genes down-regulated in comparison of B cells versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "SHTN1,ARRB1,LDLRAD4,CACNB2,CCNT1,LRRFIP1,CX3CR1,CNIH3,ABCC5,EDN3,FCF1,EPHA5,EXTL2,FABP7,STRADA,FECH,NCKAP1,CIT,GSTT2,LIFR,MAOB,MEIS1,MYCN,P2RY13,PDE3A,PENK,PLEC,PLIN1,C11orf49,LRP12,RASGRF1,LGI2,RORB,SALL1,SATB1,SH3GL2,NLGN1,ZNF365,ZCCHC24,ERC1,ZFR2,RUSC1,ANKS1B,SLC30A3,MVB12B" Coexpression M9747 Genes down-regulated in follicular helper CD4 [GeneID=920] SMARTA T cells (Tfh): effector during acute infection of LCMV versus memory. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "ACTN1,CSMD3,CCDC85A,ADCY8,PNMA8B,UNC79,ZFAT,GPR146,CFLAR,KSR1,CACNA1B,CBLN1,ENTPD6,CD81,KCNAB3,CREB5,TENM4,KIAA0040,C8orf34,CALN1,CDON,EBI3,PLXNC1,KCNMB2,ZIC4,SCML2,NBEA,TPK1,GRIK2,CD200,MXI1,HMGCLL1,PTH1R,DUSP15,RFX5,NUDT11,RPS6KA2,SH3GL3,BTBD3,SNAP25,ZNF423,RHBDL3,ADGRL3,EMX2OS,SLC17A6" Coexpression M8672 Genes up-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "TMCC3,MAP4K3,CACHD1,ASPH,NRP2,CD86,ARHGEF2,ZBED5,TPP1,ZNF385A,AATK,CSF1R,CSF2RA,VCAN,PLCXD3,CYBB,DOCK4,SIRPA,GSDME,HSD17B14,SLC43A2,IGSF6,ARMCX1,FAM198B,CHST15,FCGRT,ADAM28,GK,GLUL,LILRB4,LIFR,LMO2,MSR1,NCF2,PMP22,PILRA,LRRC49,PTAFR,SLC11A1,EPB41L3,SULF2,SLC37A2,TCF4,DMXL2,SEZ6L" Coexpression M6575 Genes up-regulated in ITGAM+ [GeneID=3684] cells from spleen: healthy versus tumor bearing mice. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "ABAT,C3orf14,RNF157,OSBPL6,C1QTNF4,PITPNM2,ARNTL,KSR1,CDK5R1,HAP1,PPP1R16B,KIAA0753,RABGAP1L,CORO2B,SGIP1,FYN,GGT7,PTPN5,CFAP126,TUBB2B,JAK2,LAMP2,SLC11A2,NRGN,NTRK3,SETD4,PDE3B,SNX10,PPP3CC,EPDR1,SLC26A11,PTPN13,RYR1,RYR3,MYO18A,SAMSN1,ZC4H2,STXBP1,KLHL4,MGRN1,ZMAT3,GZF1,EIF4ENIF1,ZFP41,GDPD5" Coexpression M5627 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] versus those treated with TGFB3 [GeneID=7043] treated with IL6 [GeneID=3569] and IL23A [GeneID=51561]. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "FAM43B,GALNT16,FUBP1,CALB1,KALRN,SCARB1,CDH10,SLC35F1,SEC14L5,DGKG,MED24,EMX2,EPB41,RTN3,CORO2B,OLFM1,DNER,SPIN1,GRK4,KCNK1,MITF,MTR,IDNK,PDE3B,PRKCB,NDUFS7,RAD17,TMEM100,STK32B,WLS,AP1AR,ARHGEF40,TMEM132D,SCN3B,EMC1,STOX1,ARL10,ELP5,TUBB2A,UBE2H,USP1,BCL2L13,TBC1D15,CLDND1,SPATA13" Coexpression M3189 Genes up-regulated in comparison of IgD+ peripheral blood B cells versus dark zone germincal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "ASIC2,NDRG3,AMT,ARHGDIG,ARSF,ASGR1,ENTPD6,TPP1,NRG2,CHD1L,ARHGAP24,ZNF337,DTNB,FIS1,PLXNC1,FHL1,FOXO3,GAA,GCK,GFER,USP19,GP1BB,DIDO1,HSPA1L,IL11RA,KCND3,KLRC3,MAN2A2,MIA2,PCDH9,PLEC,FAM120C,ZNF671,RPS6KA2,LGR4,SLA,LIMS2,GLT8D1,MYCBP2,KDM4C,RAP1GAP2,GSE1,PCBP4,CERS6,IFT88" Coexpression M6791 Genes down-regulated in lymph node B lymphocytes: influenza infection versus un-infected. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "DSCAML1,CCDC85A,ADORA2A,WDR35,ALK,PPFIA4,APBB1,CA12,KIAA1549L,NRXN2,PCYT1B,SLC25A27,FEZ1,ARHGEF4,FBXL5,FAM57B,DTNA,EIF4G2,ELAVL2,ELAVL3,RCAN2,F8,ABCA8,GORAB,TMEM175,TPPP3,MALT1,RNF165,HECTD2,MGAT3,LYRM9,SLC10A4,CASTOR1,MCMBP,ASAP3,SLC1A6,EPN2,SLC8A1,SLC20A2,SLIT1,UNC5B,SSTR1,CFAP298,REEP1,ZNF184" Coexpression M9599 Genes down-regulated in T conv: peripheral lymph nodes versus thymic CD24 high [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "BEGAIN,ANK3,FAM131A,CASK,NAE1,GYG2,CA12,SYNGR3,HOMER3,GAL3ST1,ECM2,ABCC5,PCOLCE2,EML1,ENO2,EPB41L1,CDHR1,SCARA3,CAP2,ATP6V1H,AHCYL1,COPS8,RAB40B,KCNJ9,LSS,MPP2,MX1,NRCAM,PCSK5,SERPINE2,EPB41L4B,C19orf57,PIGG,RAP1GAP,PNMA8A,FUZ,SYBU,PAAF1,CLSTN1,PALLD,SSTR1,NACC2,PDIA2,TUBA1A,ADAMTSL3" Coexpression M5419 Genes down-regulated in comparison of eosinophils versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "SYN3,ADD3,APBB1,CASK,LDLRAD4,CAST,CBLN1,CD38,CHN1,ZBED5,COX4I1,DZIP3,DLG3,CASP8AP2,PLEKHO1,ERBB2,CD320,F8,RACK1,FOLR2,USP21,SESN1,MALT1,MUM1,HSP90AA1,IL6ST,KLHL23,DPY19L2P2,SIDT1,RAD17,CARF,CCDC25,TRIM46,COPZ1,CLUAP1,CAMTA1,TCF12,DOCK9,NACC2,CBX5,NR2E1,ZMYND8,ZNF32,C12orf4,FXR1" Coexpression M8494 Genes down-regulated in mock treatment during adoptive transfer therapy of B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "ACTN1,CSMD2,ADARB2,AQP6,CCAR2,SLC4A4,BID,CD38,ENTPD2,SRSF11,PPT2,CSF2RA,DCAF8,DBN1,CDON,DNM2,ERCC2,DUSP27,EVL,GATM,TXNL4A,TNRC6A,TOX2,ATXN2L,SLC35G1,SCAMP5,DBNL,CEP41,SLC26A11,PRPSAP2,QRICH1,ACSM5,SETD5,TMLHE,STK32B,SBF1,HOGA1,AMBRA1,BTBD3,SLC20A2,SUPT5H,TMPO,CADM1,CA10,PIANP" Coexpression M8743 Genes down-regulated in STAT5 double knock-in T cells: control versus IL2 [GeneID=3558] stimulation for 17h. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "USP31,ARRB1,ALDH7A1,CANX,CAPN3,CDC25B,AKAP5,MAGED1,PUM1,MYADM,RIPOR2,SPOCK2,RHOBTB1,EXOG,RASA4,CORO2B,FUT9,SARAF,SRCAP,ATOH8,IRAK3,KCNC1,LMO1,NOVA1,PFKP,SMOX,ROM1,MCMBP,SCP2,SEC14L1,SHMT2,ANKRD6,ABLIM3,SLC9A5,RBM34,DOP1A,SPTAN1,ACSBG1,TAF6,TBL1X,HEY1,TPD52,TTC3,FLRT2,CLDND1" Coexpression M5397 Genes up-regulated in comparison of eosinophils versus mast cells. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "TAOK1,APBB2,APLP1,CHRD,ATP2B2,LRRFIP1,PITPNM3,GIT2,DBT,DGCR5,EZH1,KIAA1109,CAMKK2,STAG2,USP19,GLRB,CNTRL,TPPP,GRIA2,GSN,FICD,IL6R,JAK2,MYT1,P2RY13,NNAT,OMG,SPATA6,SAMD9,MARCH1,GAL3ST4,LGI2,CCDC82,RERGL,RXRA,SATB1,SMPD3,SLA,EPN2,IQSEC2,SAMSN1,SYNE2,TUB,HRASLS,SLC4A10" Coexpression M5759 Genes up-regulated in comparison of untreated macrophages versus those treated with IL1. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "OSBPL1A,ANK2,CDK13,NOL4,CAMK2G,SLC25A14,SLIT2,ARHGEF6,LETMD1,OSBPL3,APPL1,EXOG,KLHL5,AMZ2,TESK2,SESN1,PACSIN2,BACH2,MBP,DPY19L2P2,PCSK1,ABCB1,ZFYVE21,PDZRN4,MAGEL2,PPP2R5E,SEC61A2,GSTCD,PRR5L,TRIM46,ITSN1,KBTBD4,GLT8D1,ATMIN,LEFTY2,THRA,CABIN1,TPM1,UGT8,ZBTB14,ZNF74,WNK1,MAP3K12,PLSCR4,MARCH8" Coexpression M8562 Genes up-regulated in T helper cells 15 days post polarization: Th1 versus Th17. MSigDB C7: Immunologic Signatures (v6.0) 5.05E-03 1.00E+00 3.31E-02 3.29E-01 45 199 "ALCAM,MADD,SYNJ1,CLIP3,CSF2RA,CSNK1G3,TCAF1,ZEB2,GUCD1,FRY,SH3GLB1,NSRP1,FDFT1,ACSS1,RAPGEF4,GRIK5,GRM7,SMAP1,SCIN,DIPK1A,INPP5B,KIT,LSS,GPR155,PPP2R5C,CEP97,SYNDIG1,WLS,PEAR1,TRIM46,ASRGL1,FAM214B,INAVA,CEP68,TMEM150C,FRYL,THRA,UBE2H,VIPR2,MICAL1,ATP6V0E2,UPF3A,TUBA1A,ZDHHC20,SENP7" Coexpression M2131 "Genes up-regulated in RS4;11 cells (MLL, mixed lineage leukemia) in response to SB216763 [PubChem=176158], an inhibitor of GSK3B [GeneID=2932]." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.06E-03 1.00E+00 3.31E-02 3.29E-01 81 397 "ABAT,ALCAM,AMPD3,FGD2,CCDC146,MYOM1,BBS2,SCAPER,C5,CACNA1E,ZNF555,SHISA7,RCBTB2,MS4A7,KMT2C,LY86,LETMD1,SEC31B,CREB5,CSF3R,IPCEF1,DZIP3,CTNND1,CCDC144A,ZFYVE16,PITPNC1,ELMO1,DTNA,SEZ6L2,SIDT2,GPHN,GTF2IRD2,KIAA1109,FYB1,GAA,TRAF3IP2,MTHFD2,WASHC2A,GFRA2,ATF7,ATG4C,IGF1,LIG4,SESN3,MYO5A,AMZ2P1,NCAM2,NCF2,PDE1B,ENPP2,HERC2P3,PRKCB,TMEM260,ZYG11B,CARF,ATP8B4,ACER3,ATXN1,MYO18A,R3HDM2,CDK5RAP3,SLC15A2,CPEB4,RCOR3,TTC17,SNRPN,SPTAN1,COLGALT2,STXBP1,SLC37A2,AGTPBP1,DMXL2,AHCYL2,CYB561A3,ZMAT3,ANKRD20A2,SSBP2,ZNF138,SIGLEC10,KLHDC1,SENP7" Coexpression 15013775-Table1 Human Leukemia_Fu04_32genes GeneSigDB 5.08E-03 1.00E+00 3.32E-02 3.30E-01 11 31 "BIN1,CDH2,CRMP1,FCGRT,OLFM1,GATM,MN1,PBX1,PTPN13,TNNT1,FNDC5" Coexpression 15520196-SuppTable6a Mouse Breast_Bae04_94genes_BRCA1null_down GeneSigDB 5.08E-03 1.00E+00 3.32E-02 3.30E-01 23 86 "NDRG3,ADD3,NCOA1,CCPG1,NCOR1,CASP8AP2,USP16,GFRA1,GPT2,SMAD1,MEF2C,NFE2L2,ENPP2,USP47,EPN2,CDK19,TCF12,TGFBR3,TJP1,NR2C2,TTC3,UBE3A,VLDLR" Coexpression M2991 Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM. MSigDB C7: Immunologic Signatures (v6.0) 5.15E-03 1.00E+00 3.37E-02 3.34E-01 37 157 "SYS1,CASKIN1,LRWD1,IGLON5,SH2B1,KBTBD11,USP3,FAM135B,EFNB3,LPAR6,FCGRT,EVL,FOLR2,NPTN,TMEM25,ATOH8,GABARAPL2,MAN2A2,PPM1L,MN1,MOG,PDCD2,SEMA5B,NLE1,SIDT1,PTPRN2,SLC6A15,PRIMA1,CLIP1,GALNT10,DZIP1,UHRF1BP1L,SSPO,KANK1,JMJD6,CAMSAP2,TCF7" Coexpression 16289389-TableS1 Human Lung_Hoang05_181genes GeneSigDB 5.15E-03 1.00E+00 3.37E-02 3.34E-01 37 157 "APP,NCOA1,MTMR9,BTRC,ENTPD6,CLTB,PPP1R16B,KIAA0586,RABGAP1L,DMPK,EPB41L1,RASGRP2,SRRM1,F5,GAD2,CPLX2,GLUL,ARHGAP19,HP,IRF8,L1CAM,MBNL1,MGAT3,MYO6,P2RY13,PRKCB,DZIP1,RIMS1,FNBP1,MYCBP2,NFASC,CLASP2,GSE1,ZFR2,LILRA4,UBC,SLC17A7" Coexpression M12085 Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing erythroid lineage. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.18E-03 1.00E+00 3.38E-02 3.36E-01 14 44 "DDR1,CH25H,HOMER3,CREM,CRHBP,VCAN,ARMCX2,LILRA2,IFI16,CD200,NRCAM,IL17RB,TCF7L2,UCHL1" Coexpression M2698 Genes up-regulated in NCI-60 panel of cell lines with mutated TP53 [Gene ID=7157]. MSigDB C6: Oncogenic Signatures (v6.0) 5.21E-03 1.00E+00 3.39E-02 3.37E-01 44 194 "BCAR3,AMPH,APBB2,AZGP1,SYNJ2,CALB1,FOXN3,SLIT2,TJP2,CNN3,CNR1,HAPLN1,CLIP3,LRIG1,HDAC9,SCRN1,RABGAP1L,DMD,EDIL3,SH3GLB1,EGFR,F3,REEP2,EFEMP1,KHDRBS3,FYN,ZNF44,TOX3,GLUL,GP1BB,GRIK2,INPP1,MEIS2,MEST,GPSM2,PTN,PTPRH,ZNF415,NMNAT2,CAND2,UCHL1,UGT8,USP1,SCG2" Coexpression M2861 Genes down-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 5.21E-03 1.00E+00 3.39E-02 3.37E-01 44 194 "C3orf14,ADRB2,SEMA6A,ATP2B1,NRP2,WASF1,MAP7,CNTFR,COL4A5,COL11A2,HDAC9,SIRPA,POM121,GAP43,MALT1,PCLO,SMAP1,VWA5A,AFDN,NEUROD2,PCBP3,OMG,PAK3,CDK18,CAMKV,EPB41L4B,C1orf109,RAB3IL1,RET,C12orf49,SCN2A,ARFGAP1,KIF21B,SP2,ARHGAP26,SYP,COBL,ROBO3,SYNE1,SEZ6L,CDK20,RPRM,UCHL1,SLC30A3" Coexpression M6508 Genes up-regulated in monocyte-derived dendritic cells: LPS versus vehicle. MSigDB C7: Immunologic Signatures (v6.0) 5.21E-03 1.00E+00 3.39E-02 3.37E-01 44 194 "ACTN1,RNF157,ESYT2,ABCD2,MRTFA,PITPNM2,USP6,CD38,TBRG4,NOG,CNN3,IPCEF1,KIAA0319,KLHL3,SPOCK3,EPB41L2,BAIAP2,ZBED3,RAPGEF6,ATP8A2,ARFIP1,USP19,GPR22,BACH2,MYLK2,FXYD7,KSR2,NUCB2,ENPP2,SDK2,PRKAR1B,FITM2,SNRK,GAL3ST4,RFX2,RFX4,PTGR2,SEMA6D,SELL,BTBD3,SYN2,MLST8,TCF7,METTL3" Coexpression M2850 Genes up-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [Gene ID=3205] gene by RNAi vs controls. MSigDB C6: Oncogenic Signatures (v6.0) 5.21E-03 1.00E+00 3.39E-02 3.37E-01 44 194 "CLK4,GAS7,SHTN1,CD86,RCBTB2,PLAA,MAP4K4,IFFO1,ENTPD4,CSNK1G3,IPCEF1,VCAN,HDAC4,ZFYVE16,FBXL5,ANKRD46,FRY,KMT5B,LPAR6,RPS6KC1,ST3GAL6,FCGRT,TPK1,FYN,GALC,SESN1,IFI16,JAK2,NCF2,SNX10,SCHIP1,PTPRE,ROGDI,ATXN1,FNDC3A,SLC22A4,UHRF1BP1L,ARHGAP26,AGTPBP1,DICER1,ZMAT3,THBS4,SGK3,PHTF2" Coexpression 18689800-TableS6 Human EmbryonicStemCell_Thomas08_113genes GeneSigDB 5.25E-03 1.00E+00 3.41E-02 3.39E-01 28 111 "FUBP1,CREM,ARNT2,NR1D2,E2F5,ETV1,FOXM1,BRD8,GLI2,ATF7,SOX21,SMAD1,MBD1,MEIS2,AFF1,MYCN,NFYA,PAX6,PBX1,RXRA,SALL1,SATB1,HES6,SOX2,TCEA1,HIRA,ZNF24,PRDM2" Coexpression M17044 Genes with the high-CpG-density promoters (HCP) that were up-regulated in 1542-CP3TX cells (prostate cancer) compared to 1542-NPTX (normal prostate). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.25E-03 1.00E+00 3.41E-02 3.39E-01 28 111 "DGKD,CDK10,PDXK,FUBP1,SOCS6,NCOR1,B3GAT3,SIDT2,ST3GAL6,FGFR1,FOXO3,FLNC,TACC2,PDLIM5,CSPG5,GAD1,SYT17,GRB10,NR3C1,MEIS2,AFF1,NEFH,RETREG2,SGK1,SHMT2,SPTAN1,MAPK8IP3,WWC1" Coexpression 15757864-Table4 Human Thyroid_Forberg05_80genes GeneSigDB 5.25E-03 1.00E+00 3.41E-02 3.39E-01 19 67 "APBA2,CACNB2,CDH2,CHN1,NRG2,FEZ1,SACS,ERBB4,GAD1,MAOB,MYO5A,NUCB2,PC,PLIN1,PTHLH,SELL,TF,CADM1,ZBTB16" Coexpression 15073113-Table4 Human Testicular_Sugimura04_30genes_NeuroectodermalTumor GeneSigDB 5.26E-03 1.00E+00 3.41E-02 3.39E-01 10 27 "KDM5D,ATP1A3,ARNT2,GJB1,KIF5C,MAP6,NAP1L3,NPTX2,UCHL1,SLAIN1" Coexpression M10773 "'Wilm's tumor signature': genes highly expressed in Wilm's tumor samples compared to normal fetal kidney and a heterologous tumor, Burkit lymphoma." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.26E-03 1.00E+00 3.41E-02 3.39E-01 10 27 "APOC1,BRINP1,LYPD1,CHRDL1,EYA1,FOXG1,WASF3,HAS2,MN1,NNAT" Coexpression 19334046-TableS3b Human Lung_Boelens09_135genes GeneSigDB 5.26E-03 1.00E+00 3.41E-02 3.39E-01 27 106 "OSBPL6,CC2D2A,CEP126,STK33,BBS2,CAST,RGN,LRWD1,NCOR2,LRIG1,PPP1R16B,DNAH9,EFEMP1,ZMYND10,AK8,ACSS1,GPR162,AFDN,FTO,EXOSC10,FHOD3,EPN2,SLC22A4,SYNE1,TPM2,TUBB2A,CFAP52" Coexpression 18378853-Table3a Human StemCell_Langer08_29genes GeneSigDB 5.26E-03 1.00E+00 3.41E-02 3.39E-01 9 23 "C1QTNF4,PROM1,B4GALT6,KIT,MN1,CD200,ABCB1,BAALC,ITM2C" Coexpression 19269367-TableS2 Mouse StemCell_vanderFlier09_33genes GeneSigDB 5.26E-03 1.00E+00 3.41E-02 3.39E-01 9 23 "ADORA1,LGR5,AQP4,CRLF1,PSRC1,PTPRO,TNFRSF19,SLC12A2,SLC14A1" Coexpression M8108 "Genes up-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen, raloxifene, or ICI 182780 but not by estradiol [PubChem=44959;5035;3478439;5757]." MSigDB C2: CGP Curated Gene Sets (v6.0) 5.26E-03 1.00E+00 3.41E-02 3.39E-01 9 23 "LDLRAD4,DGCR9,PLXNC1,AKAP3,RAB30,NCAM2,SCHIP1,AHCYL2,TPM1" Coexpression M17312 Genes up-regulated in MZ128 cells (Wilms tumor with mutated WT1 [GeneID=7490]) after treatment with 10 microM tretinoin (ATRA) [PubChem=444795] for 24 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.26E-03 1.00E+00 3.41E-02 3.39E-01 9 23 "AKAP12,ETV1,DLC1,KIT,CLDN11,PDGFRA,KANSL3,TAL1,NAV2" Coexpression M6296 Genes up-regulated in macrophages stimulated by IFNG [GeneID=3458] for 3h: control versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 5.31E-03 1.00E+00 3.43E-02 3.41E-01 40 173 "PHF12,MADD,SCAPER,AIFM1,LETMD1,TOMM20,IRAK4,USPL1,TUBD1,RRAGB,RACK1,SARAF,RAPGEF6,CRCP,INPP1,INPP5B,VWA5A,NACA,SIDT1,PTPRE,RAD17,RGS10,PCMTD2,CLIP1,SELL,WDR37,RUFY2,ANKFN1,NACAD,CAMTA1,SIN3B,TCF7,DDHD1,NR2C2,UBC,UBTF,INTS3,CAB39L,UBE3B,GAN" Coexpression M2818 Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL15 [Gene ID=3600]. MSigDB C6: Oncogenic Signatures (v6.0) 5.38E-03 1.00E+00 3.43E-02 3.41E-01 43 189 "ASPHD1,ACTN2,PWWP2A,ADRA1B,ABCD2,MYH7B,PROM1,CACNA1E,LOC730101,CLGN,CNTN1,AKAP5,CRHBP,ARHGEF10,ERC2,RHOBTB1,DTNB,TOM1,TMEM35A,EPS8,RASL12,EYA1,CACNG3,ATP8A1,SESN1,LYVE1,KCND1,CLDN11,PLCL1,C19orf57,LGR4,KCNIP2,SEMA6D,SCN3A,SLN,SNRPN,SOX15,ATP10B,SYT1,CUX2,PCDHB3,BHLHB9,PARP11" Coexpression M7123 Genes up-regulated in peripheral blood monocytes (PMBC): healthy versus mixed infection sepsis. MSigDB C7: Immunologic Signatures (v6.0) 5.38E-03 1.00E+00 3.43E-02 3.41E-01 43 189 "ADORA1,AMH,LRRC4C,ATP2B2,TTC9B,LRWD1,CABP1,RIMS4,PARD6A,CHRDL1,DMPK,EEF1A2,EFNA3,TMEM132E,TENM1,TNK2,ANKRD13B,NEURL4,ILDR2,CPLX2,RND1,DCLK2,GRIK4,HPCA,SHISAL1,SLC6A17,ADAM11,PAX6,PDE1A,PRRX1,PROX1,CRTAC1,RGS7,RNH1,CPEB3,FAM81A,MAST1,MYH15,PDZRN3,DDN,WWC1,NR2F1-AS1,PCDHB9" Coexpression M1892 Genes up-regulated in dendritic cells (12 days): control versus 25-hydroxyvitamin D3 [PubChem=1593]. MSigDB C7: Immunologic Signatures (v6.0) 5.39E-03 1.00E+00 3.43E-02 3.41E-01 35 147 "FZD9,APAF1,API5,BID,LDB2,LGI1,CHRNA4,CEP170,CHRDL1,CPEB2,POLK,NOP56,NBEA,TPK1,LILRB4,PSIP1,ADAMTS6,HECTD2,PPM1L,XRRA1,NELL1,NF1,P2RX7,KCNK10,ZIK1,SCN7A,HSPA4L,SLC20A2,UHRF1BP1L,STOX1,ZSCAN29,FAM168A,TMEM237,DNALI1,ST8SIA2" Coexpression M2972 Genes down-regulated in natural T reg: wildtype versus non-functional FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 5.39E-03 1.00E+00 3.43E-02 3.41E-01 35 147 "ADRA1D,N4BP2L1,CLGN,ADGRG1,FOXN3,PITPNC1,ZEB2,CPEB2,KMT5B,EIF1,LRRC23,DNAJC27,TPPP3,FAM120B,ATP8A2,ATF7,NR3C1,GRM8,PSIP1,LRRC75A,DOCK7,KIF5C,KLRC2,CHIC1,SERPINI1,SEPT4,PPM1B,SLC22A23,KCNIP3,WLS,CHD9,ZFP1,ANKRD12,ZFP90,TTC3" Coexpression M1747 Genes with promoters bound by FOXP3 [GeneID=50943] and which are down-regulated only in developing (located in the thymus) regulatory CD4+ [GeneID=920] T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.47E-03 1.00E+00 3.43E-02 3.41E-01 6 12 "AMPH,CADPS,MAP4K4,APH1A,EPB41,ZBED3" Coexpression 19855078-TableS5 Human Leukemia_Stumpel09_75genes GeneSigDB 5.48E-03 1.00E+00 3.43E-02 3.41E-01 20 72 "ADCY2,PROM1,ENTPD6,NOG,CRCP,GLDC,NR3C1,MAEL,SLC6A17,ITPKB,INSYN2,KCNK10,LRP12,BSDC1,NPAS3,SYN1,PCDHB15,ICAM5,ZFP41,SOCS4" Coexpression M8488 Genes up-regulated in mock treatment during adoptive transfer therapy of B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,SLC25A25,ADORA2A,CARNS1,BCAS1,CCAR2,SLC4A4,N4BP2L1,SCAPER,ZNF445,PCYT1B,AKAP6,SNPH,DCAF8,KCTD8,DNM2,NCALD,TMEM74,SIRPB1,CHL1,GJB1,CLASRP,DISP2,DBNL,SERPINI1,SNX10,RANBP3L,PTCH1,EML5,RGS12,SETD5,STK32B,RTN1,SLC20A2,IZUMO4,MAPK8IP3,SUPT5H,TMEM150C,TPCN2,ARHGAP9,TNS1,NPL,DCBLD1,SLC38A1,CPNE4" Coexpression M4884 Genes up-regulated in comparison of naive follicular B cells versus early germinal center (GC) B cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "APC,DNAH17,CCDC181,RAB26,NCOR2,ARHGEF10,PDE4DIP,CYBB,B3GAT3,ZC3H11A,DPP6,E2F5,EBF1,SNX29,KAT8,ANKFY1,ZMAT1,TNRC6A,ZNF638,KIAA1958,HTATSF1,GP1BB,GUCY1A2,CELF3,DHX35,LAMA2,NFE2L2,PDCD2,PIK3R1,ZNF655,MED1,MINDY2,PTPRN,MARCH1,PID1,BSDC1,SAFB,SCAF8,MBD5,MYCBP2,FAM168A,CDH22,RFTN2,KLC2,ELFN1" Coexpression M6549 Genes up-regulated in CD8 T cells: control versus over-expressing TERT [GeneID=7015]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "RBM10,RNF157,APBB1,SEC11C,TRIM41,CAPN3,FMNL3,CD81,TJP2,PCYT1B,SLC4A7,ACBD5,CNRIP1,YTHDC1,RABGAP1L,EBI3,TUBGCP4,B4GALNT4,STON1,ADAMTS6,ATG4C,ACOT7,LRRC75A,TUBB2B,KIF5C,MATN2,MYO5A,ZNF862,NUMA1,ZNF827,SYTL2,PTPN13,WLS,KIF16B,MYO18A,ANKRD6,GKAP1,STX1A,ACSBG1,C3orf70,ARHGEF12,TUBB2A,VAV2,MSRB3,ZDHHC20" Coexpression M6096 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL-12 (6h). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,APAF1,MADD,GPR146,SLC25A14,SPAG9,COL9A3,KIAA0040,GIT2,ZC3H11A,KBTBD11,RASGRP1,SIDT2,EGR3,LPAR6,SEC23B,C2orf88,SARAF,INPP5K,GPR162,CNTRL,SYNPO,IRF8,IL6ST,INPP1,TUBB2B,MATK,AFF1,PDE4B,PDE1B,RC3H2,SNRK,RGS10,FAM102A,FAM126B,TNIK,MYCBP2,SULF2,PJA1,SLC44A1,C9orf85,WIPF1,TUBA1A,MPPE1,DOCK8" Coexpression M6028 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus TGFB1 [GeneID=7040] and IL-12 (48h). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ABR,WDR35,FAM135A,EPB41L5,CDC14B,CARMIL3,BBS2,RGS9,KSR1,IL33,CACNA1D,SLC4A8,PDE4DIP,UBXN2A,C15orf41,GGT7,KIAA1958,GNG3,TOX2,SLC35G1,KLHL23,VWA5A,FGFBP3,MYO6,C11orf49,SUSD4,RGS7,RGS10,TMEM100,FHOD3,ZNF365,SLC9A5,SPATA7,RAP1GAP2,ATP10B,ELOVL4,COBL,DMXL2,ARHGEF12,ZMAT3,TGFBR3,ELP5,DCBLD1,VSNL1,MICU3" Coexpression M9665 Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 1h versus 42h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "OSBPL1A,LTBP4,CNTNAP1,SEC11C,C5,CACNA1B,CACNA2D1,CANX,CCKBR,EPS15L1,CNGA3,PNKD,AKAP12,VCAN,FBXL5,CDON,DMTF1,ELAVL4,ZIC4,FGR,FOXG1,COQ5,TPPP3,GATM,SRCAP,STMN2,GYG1,HSD17B1,INSM1,KCNH2,MAG,NNAT,OGG1,PDE1A,PDGFRA,FXYD1,EPB41L4B,POU3F4,PKIA,BCAS3,RGS7,DCUN1D2,SCN3A,HSPA4L,KIF1B" Coexpression M4043 Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,DSCAML1,ADCY8,SYT13,ANXA7,GAS7,CA4,CD86,ENTPD2,TJP2,CS,VCAN,FAM107B,DNAJB6,FEM1B,CALCRL,EIF1,FOXF2,PDLIM5,GDF9,HPGDS,RAB30,RFFL,GUCY1A1,HMGB1,IRF8,KTN1,VWA5A,SMAD1,CD200,MX1,OLR1,GPR85,DUSP26,PTCH1,PKNOX2,SLC12A4,EPC1,SMARCE1,SPTAN1,SIN3B,TIMP4,UBE2H,PMEPA1,SLC38A1" Coexpression M6263 Genes down-regulated in CD8 T cells: healthy versus CLL (chronic lymphocytic leukemia). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACHE,CNIH2,DDO,APOC2,PPFIA3,RNF182,B3GALT2,CALB2,CH25H,CRLF1,MAGED1,ATRNL1,HDAC9,BRINP1,TMEM130,G3BP2,DTNA,RASGRP2,TAOK3,PPP1R1B,FYB1,GCNT2,HP,RBPJ,IL12A,NCAM1,SLCO1C1,ALDH1L2,KCNK10,SMOX,RPE,RIMKLA,SCN4B,SLC1A2,SLC4A3,SNCA,TROVE2,ANKRD12,AZIN2,CCDC173,CLHC1,DNAJC12,LMF1,ZFP37,CERS6" Coexpression M9652 "Genes up-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23." MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADAR,AXIN2,SLC12A5,AMPD3,MAP4K3,PKP4,API5,ARNTL,ST3GAL5,CH25H,RGN,RTTN,C2CD2,CS,CSF1,FGFR1OP2,DBI,PITPNC1,TOM1,SPEG,F8,AMZ2,FOXM1,SEMA4D,GJB1,GLUL,IL12A,IPO5,SETD4,SCHIP1,PTCH1,PTX3,RDX,SEMA6D,CASC3,FNDC3A,SPTAN1,NCDN,GANAB,SYP,TCEA1,DDHD1,ZBTB14,RNF103,FRMD6" Coexpression M3675 Genes up-regulated in comparison of T effector cells from uninfected mice versus T effector cells from mice infected with S. mansoni. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,ADD1,ADD3,ADRB2,AP2A2,SORCS2,PCDH10,AMPD3,FGD2,SFMBT2,NUMB,CAST,CHRNA4,CNN3,RIPOR2,SRPK3,LRRC23,TLR7,SEC24B,GFRA1,ATF7,PADI2,BTBD17,MEF2C,MAPKAP1,PPP3CA,PRPSAP2,RIPOR1,ERI2,MCMBP,LRRK2,GALNT10,SCAF8,MYO18A,LMBRD1,MYCBP2,KDM4C,STX1A,KLHL7,METTL3,UBTF,SPHK2,ZNF142,CAB39L,FAM13C" Coexpression M7480 Genes down-regulated in periperal blood monocytes (PBMC): tolerant kidney transplants versus healthy controls. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,LGR5,BACH1,LDHD,SGCE,CD81,ABCG2,CSNK1E,GIT2,ELMSAN1,DMD,TRAPPC9,OPTN,ELAVL3,ATP8A1,BRPF3,GLUL,KIAA1958,GRB10,GSN,IRAK3,INPP5B,KCND1,KCNJ10,GPR155,MEIS1,CD200,ZNF862,NCAM2,NFIA,ZNF827,CCSER2,GDPD1,ATAT1,CCDC112,EPC1,SMARCC2,STXBP1,KAZN,PDLIM2,SIK3,TIE1,ZMYND8,BEST1,KLHDC1" Coexpression M5679 Genes down-regulated in comparsion of ActCD8 versus ActCD8TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "PLEKHH1,ARHGAP5,ATP1B3,STX16,MTMR3,BAIAP3,LDLRAD4,BTRC,ZNF445,QKI,TBPL1,LRIG1,RIPOR2,TOX,PLEKHA1,ELAVL4,STX2,TLR7,SPECC1,MEGF10,GLRB,KIAA1958,TDRKH,B4GALNT4,GPR34,ADAMTS6,KCNB1,SHC3,MYO9A,SERPINI1,RC3H2,PACSIN1,POU6F1,SNRK,MDGA2,SUGCT,NTNG1,FNDC3A,TTC17,SOX1,TNFRSF1B,TRIO,CADM1,CERS6,SLC4A10" Coexpression M6372 Genes down-regulated in bone marrow-derived mast cells: wildtype versus ADCYAP1R1 [GeneID=117] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "RBM10,ESYT2,AP1B1,GPRASP2,STK33,LDHD,ARHGEF7,CA8,CAMK2D,CDH2,ZMYM4,STOML1,SEC24C,ZNF804A,KBTBD11,BSCL2,VPS13B,PTK2B,SPSB4,EVL,PNMA2,GALC,C15orf41,GGT7,B4GALNT4,GSN,GSTT2,CD200,MSRA,NFE2L2,LAMA1,EML5,SATB1,SELL,RADIL,SLC15A2,CLUAP1,SPP1,ZBTB43,SYNE2,ZMAT3,ZIC1,WIPF2,SLC17A6,UBE3B" Coexpression M7345 Genes down-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 versus those then stimulated by T cell membranes. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "GALNT13,CASKIN1,PCDH10,ATP1B3,SLC5A11,LRRC3B,ELAVL4,PAN3,HSD17B14,EPHB1,RAB9B,POLR1B,FGF12,SGIP1,GABRA1,ZNF276,KCNMB4,FAM107A,UBE2QL1,NXPH2,ELOVL5,HNF4G,GAREM2,IL12A,LYPLAL1,ERICH3,TAGLN3,KCNK10,PHKG1,POLR2F,PRPH,PTPRN2,SLC25A48,SH3TC2,SUSD4,KCNIP1,SLC30A10,SLC15A2,SYT4,ICAM5,TRIO,BEST1,TMEM163,NETO1,CBLN2" Coexpression M3014 Genes up-regulated in comparison of naive versus memory CD8 T cells (day 40+ after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,ACTN1,ADAR,ADCY6,ADD1,AMPD3,SFMBT2,ARRB1,SEC11C,LRWD1,ARMCX2,USP3,ABCC5,PLEKHA1,RACK1,EVL,NSG2,SARAF,SRCAP,SESN1,GGT5,GSN,GSTT2,ELOVL5,IL6R,IL6ST,ITPKB,SMAD1,PTOV1,SERPINI1,RETREG1,QRICH1,EML5,RGS10,RPS6KA2,WLS,SATB1,SELL,FAM102A,ST6GAL1,TBCEL,METTL3,SSBP2,TTC3,SLC30A4" Coexpression M3734 Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "DSCAML1,KLHL13,LTBP4,ANXA7,CFLAR,ST3GAL5,OSGIN2,CDK5R2,HAP1,SLC16A4,AHCTF1,CP,DMTF1,DTNB,EDN1,EDNRA,SPECC1,GABRG1,HIGD1B,PTGDR2,DDX19B,HSP90AA1,ITPKB,KCND2,MMP17,MT3,MTTP,PIK3R1,PILRA,SLC22A23,PTX3,USP47,RPS6KA2,LRRK2,IFT122,BEX1,SAMSN1,SSTR2,SYT4,HEY1,NPDC1,ZBTB16,HRASLS,IFT88,SOCS4" Coexpression M4335 Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADCY6,SNX32,SEMA7A,DLGAP3,ARHGEF10,CSNK1E,AIF1L,PITPNC1,DNAJC6,DPH1,SH3YL1,ZMYND10,EVL,SPECC1,GABRA5,GPD1,RNF165,HP,IL12A,TUBB2B,ITPKA,KCNJ9,PIK3AP1,CPNE9,CCDC80,RSPO2,MX1,PDGFRA,C19orf57,ZNF493,MAPK12,PRCD,SCG5,FHOD3,SLC1A6,NAPB,SOX15,CLASP2,JMJD6,ATP11A,ACSL6,SGK3,KCNK12,ZFP37,ADAMTSL3" Coexpression M9258 Genes up-regulated in CXCR5+ BCL6+ [GeneID=643;604] follicular helper T cells versus CXCR5- BCL6- CD4+ [GeneID=643;604;920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD1,ADD3,AMPD3,GPR146,CCNT1,CFL2,CNN3,LRIG1,WDR20,NR1D2,ATN1,RACK1,SUCO,FOXO3,IQGAP2,ACSS1,NR3C1,IRAK3,PADI2,BACH2,DIPK1A,HECTD2,PPM1L,PDE4B,PFKFB2,PLCB2,MINDY2,PPM1B,PTK2,RAD52,RNF220,TMEM206,MCMBP,SELL,ST8SIA1,DZIP1,WDR37,SULF2,KIAA0930,RGMB,TRIO,TTC3,SGK3,PPP1R3F,MPPE1" Coexpression M8038 Genes up-regulated in CD8 T cells: control versus stimulated by IFNA2 [GeneID=3440]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "OSBPL8,DGKZ,MARCH3,RAB29,CD38,RAB33A,CLCN3,RCHY1,AHCTF1,ARHGEF4,ZFYVE16,GOLGA7,DENND4A,FABP7,ATP8A1,FLT1,ZNF274,MALT1,PRRC2B,GRB10,IL6ST,MBD1,PDE3B,PLEC,PPM1B,PPP2R5E,PPP3CA,CYBC1,GTDC1,MAP6D1,S100B,RAB3GAP1,SMARCD3,DOP1A,PJA1,MCF2L,TBL1X,PUM2,ZMYND8,UBTF,ZNF24,PCBP4,MPPE1,UBE3B,JMJD1C" Coexpression M7694 Genes up-regulated in mouse embryonic fibroblasts (MEF): wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ALCAM,ANK1,PPFIA2,BMPR1B,MYRIP,CDC42BPB,PPP1R16B,PPP6R2,KIAA0753,SACS,LRRC17,ERBB2,FGFR3,GALR1,SOX21,GUCY1A1,SYNPO,DIPK1A,KLC1,NODAL,KCNK10,PAK3,SERPINE2,PLIN1,RC3H2,POU3F4,TTLL7,KLHL11,ZFHX4,MYH14,WLS,SCN3A,SCAF8,PKNOX2,SLC12A2,SPTAN1,CLSTN2,APOM,SYN2,SMG6,ZMAT3,TIMP4,TRO,TUB,ZNF154" Coexpression M8311 Genes down-regulated in naïve T cells: CD4 [GeneID=920] versus NK. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD3,ADRB2,BIN1,AMT,CDC42BPA,CDC14B,CADPS,RGS9,RHBDL1,CDC25B,CHI3L2,ASIC3,SEC31B,SDC3,SIRPA,OPTN,SORBS3,MRNIP,EN2,RASGRP2,PTK2B,FCGRT,FGFR1,FGFR3,TRAF3IP2,DISC1,USP19,PADI2,IL11RA,MATN2,AFDN,NUMA1,OCRL,PLCD1,PLIN1,PRRX1,MAPK3,PSD,PTX3,IZUMO4,FCHO1,MCF2L,CDH22,ZKSCAN5,GDPD5" Coexpression M4314 Genes down-regulated in comparison of TregLP versus Homeo Convert (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ALAD,CALB1,CACNA2D2,FAM171B,LRRC3B,MYADM,RIPOR2,RASSF2,SMC2,GABRA2,MTHFD2,KIAA1841,GCNT2,GNAL,IL1RAPL1,IL6R,ITPKA,STMN1,NEK1,ALDH1L2,NINJ2,NME4,ENPP2,NALCN,GPSM2,PLCD1,FXYD1,SPATA6,MAPK3,RPL38,DGLUCY,SATB1,ERC1,BEX1,TTBK2,SYT11,CAMSAP2,GPRIN3,VWCE,TNS1,TPM3,EML6,TMEM178A,CERS6,ACTR3B" Coexpression M5169 Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (5 worms/well). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ABCF1,KDM5D,BARD1,CCNH,ARHGEF1,CDH8,CLTB,CNN3,PCYT1B,ZNF337,MATR3,B3GAT3,DOCK2,DYRK1A,SEMA3D,OPTN,ATP6V1H,SARAF,FYN,TCERG1,RNPS1,HTR2A,ITPKA,KIF2A,MOBP,SERPINE2,MAPK3,PROX1,PRPH,NDUFS7,SNRK,RPS6KA2,SARS,CNKSR2,SOX2,IQSEC2,ST5,TAF9,FBXW11,CLASP1,KAT6B,TSC2,CADM1,CLDND1,RTN4" Coexpression M9136 Genes down-regulated in CD4 T conv: control versus over-expression of FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD1,DOCK11,BACH1,CBR1,CD38,CD81,ZNF445,CCPG1,CNN3,ABCG1,RIPOR2,ARHGAP24,TBC1D5,USP3,MED12,RCAN1,GNE,RASGRP2,TLR7,FOXO3,ZMYND11,ZNF274,IRAK3,KCTD6,CD200,MXI1,NUCB2,SERPINI1,SPATA6,RDX,RNASEL,PCMTD2,MAPK12,SATB1,ATXN1,SGK1,ATF7IP,MYCBP2,FAM168A,CYB561A3,TK2,ZKSCAN5,SSPN,KLHDC1,GAN" Coexpression M9459 "Genes down-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 6 versus memory at day 30." MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "MTA3,TXNDC16,FGD2,MAP4K3,APC,DNAH17,CDK11B,NCOR1,PPP1R16B,ZC3H11A,DMTF1,PHC2,SIDT2,EIF1,LRRC23,RASGRP2,TAOK3,FCGRT,EVL,TPK1,AP4B1,CAB39,INPP5K,EML4,RAPGEF1,NR3C1,ELOVL5,IRF8,SFXN5,NFE2L2,PDE2A,ING3,PRKCZ,PLEKHB2,C1orf54,BSDC1,EXD2,LRRK2,RASA3,FAM214B,SMG6,NSD1,SGK3,PRDM2,ADAMTS10" Coexpression M8763 Genes down-regulated in CD16+ monocytes versus dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "RNF150,AMPD3,LCORL,STX16,N4BP2L1,PTBP2,REPS2,CDC25B,B4GALT6,ANKRD44,CYBB,GIT2,FAM107B,CPEB2,SIDT2,TLR7,EZH1,PTK2B,ATP8A1,FCGR1A,FER,CAB39,ZMYND11,IQGAP2,BRD8,KIF3A,NCKAP1L,IRF8,PAXBP1,LMO2,PIK3AP1,PMP22,RASGEF1B,BSDC1,ATP8B4,ZKSCAN3,FNBP1,DBNDD2,FGD4,SLC37A2,PDLIM2,PRR18,GDPD5,SNX27,PIANP" Coexpression M6184 Genes down-regulated in double positive thymocytes from: B6 versus NOD mice. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "RALGAPA1,GRAMD1B,PITPNM2,SFMBT2,STX16,BRSK2,CBR1,FMNL3,ENTPD6,LGI1,EARS2,ELMSAN1,E2F5,RASGRP1,EGR3,C8orf37,RCSD1,ECSIT,EZH1,CORO2B,PPP1R1B,SUCO,MEX3B,INPP5K,ELOVL5,AGBL5,JAK2,KIF5C,GPR155,MIA2,MTR,NUMA1,PENK,MBOAT7,PTPRE,PEX2,RAP1GAP,SCP2,ZNF667,RCOR3,KLHL7,TCF12,RGMB,METTL3,CERS6" Coexpression M5831 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,CLK4,ACTN1,ADCY6,SFMBT2,CASK,SEC11C,CANX,SLC25A14,MAP7,ABCG2,CNN3,RNF14,CSNK1E,DLG3,FARSB,PLEKHA1,MRPL37,NSG2,HBS1L,SESN1,GGT5,GPD2,IL6R,IL6ST,KIT,NASP,RETREG1,POU3F4,PRKCB,QRICH1,EML5,RGS7,RPS6KA2,ST6GAL1,ZFP1,TCF4,SLC44A1,TNNT1,TTC3,LAT2,ZFAND5,SLC30A4,TUBA1A,PHTF2" Coexpression M8271 Genes down-regulated in B lymphocytes stimulated by anti-IgM: 3h versus 16h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "PKP4,ALS2,CHID1,ZMYM4,TIGD7,ARHGEF6,PHF14,KMT5B,EGR3,ZNF512,ZMYND11,ATE1,LINC01550,AFF1,MYH3,NELL2,NRDC,PDE3B,C11orf49,PPARA,PPP3CB,CEP41,PIGG,GSTCD,RMI1,DOCK10,CHD9,USP33,TRERF1,ERC1,CDK19,TAF6,EXOC7,FAM208A,IQCE,EHBP1,TCF12,AHCYL2,C18orf54,TSC1,CCDC14,PDSS2,DOCK8,ZNF37BP,RNF170" Coexpression M4504 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "LTBP4,BIN1,LRBA,CDC25B,PLEKHB1,RAB33A,MAGED1,LRIG1,FAM169A,GPRASP1,SNPH,TOX,SPOCK2,KLHL3,PLEKHA1,ENO2,SH3YL1,SESN1,BACH2,HSF2,KIF5C,NAP1L3,NELL2,NUCB2,PDE4D,PIK3R1,RETREG1,LRRN3,PKIA,SIDT1,ZNF331,FAM102A,HKDC1,TNIK,KIF21B,MPRIP,SYNE2,DNAJC9,PJA1,MCF2L,DOCK9,AKTIP,TPD52,SLC38A1,ITM2C" Coexpression M5715 Genes down-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "DGCR6,SMIM17,ARHGAP5,SNAI3-AS1,SEC11C,CHM,TMEM184B,AKAP7,SLC4A7,SLC12A6,DENND4A,OLFM1,FLT1,GHDC,GPT2,GPR34,GRK4,JAK1,KHK,SMAD1,SESN3,JAKMIP3,FXYD7,NF1,VWA2,KCNK10,PHKG1,PURG,RAB3A,PTGR2,HES6,CHD9,YPEL4,INTS9,SOX3,EMC1,SPTAN1,SYPL1,TAF6,EHBP1,USP22,PCDHB10,NSD1,SSBP2,VAV2" Coexpression M390 Genes down-regulated in 4 day cultures of bone marrow progenitors: wildtype versus MIR223 [GeneID=407008] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "SRPX,APBA2,RASL11B,KIF1A,C1QC,VSTM2A,CD86,CHRNA4,CPS1,HAPLN1,DBN1,RABGAP1L,SRPK3,KHDRBS3,GABRA2,CHL1,GABRB1,DNER,KCNMB4,CNTRL,RBPJ,MARK1,CHIC1,CD200,MPP2,NOS1,PDE4A,PGAM2,XRN1,PCDH18,PROX1,TMEM260,KHDRBS2,BAALC,RXRA,TNFRSF19,ITSN1,SLC8A2,SLC20A2,MAST1,PALLD,EPB41L3,ZFR2,P2RY12,SPHK2" Coexpression M3431 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes stimulated with anti-Valpha2 antibodies versus CD4 [GeneID=920] CD8 thymocytes stimulated with anti-beta5 antibodies. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,CLK4,NDRG2,AXIN2,TBC1D14,AMH,BID,CBR1,USP2,CLCN3,MYEF2,NR1D2,DYRK1A,SRRM1,FOXO3,NSG2,SPIN1,GRIN2D,ZHX1,NXPH2,ITGAV,PACRG,MDFI,MDM4,MXI1,NRDC,OPRL1,PCSK1,PIK3CD,PPP3CA,PRPH,PXK,WLS,SCAF8,FNBP1,KDM3A,SMOC1,PHLDB1,TBCEL,AKTIP,SSBP2,TUBB2A,LGI4,MKRN3,PARP6" Coexpression M9396 Genes down-regulated in day 7 plasma cells versus day 40 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "HACE1,KIF6,PI16,CNIH2,PPFIA3,CPNE5,ARHGEF7,MYOM2,PPT2,CLTC,TOGARAM2,PLXNA4,ERC2,LONRF1,JAKMIP2,ATL1,PPP1R1B,BAIAP2,RASL10A,CHL1,RND1,TOX3,ATE1,GRM3,FAM19A2,ADAMTS6,FRMD3,SHISA6,RASGRF2,RFX4,RNASE1,HSPA4L,BTBD3,NAPB,LGI3,SOX2,MCF2L,TRIM9,SPIRE1,LAMP5,TMEM163,SLC17A6,ACTR3B,NETO2,FAM181A" Coexpression M4576 Genes up-regulated in comparison of adult thymic progenitors versus fetal thymic progenitors. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADCY6,OSBPL1A,SPARCL1,ARMC12,APBB2,SYNJ2,CD86,CHGA,MYL6B,RIPOR2,PITPNC1,NR1D2,TLR7,FGF13,GAB1,GABBR1,TRAF3IP2,DNER,NR3C1,GSTM5,RASSF8,IRF8,LMO2,SYTL4,SESN3,PRKCZ,GON4L,ZDHHC14,RPS6KA2,LRRK2,SATB1,SELL,ITSN1,FAM102A,SH3GL2,ST6GAL1,SLC15A2,DBNDD2,CAMTA2,SSTR2,SYNE1,SLC44A1,KCTD2,CDK20,SLC30A4" Coexpression M7795 Genes up-regulated in neutrophils: LPS versus stimulated by CSF2 and IFNG [GeneID=1437;3458]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACLY,LCORL,MARCH3,CAPRIN2,GPR146,SLC25A14,CCPG1,MAGED1,RTTN,AKAP12,RIPOR2,SIRPA,FAM107B,TRAPPC9,ACOT8,YAF2,EXTL2,JKAMP,ADAMTS6,ZHX1,ELOVL5,ZDHHC15,STMN1,GPR155,PPM1L,MRPL42,NASP,PAX6,PRIMPOL,MINDY2,QDPR,ARID4A,UBR7,HUNK,KIF16B,FAM126B,LARP4,ANKRD28,ANKRD12,SIK3,C9orf85,RUNDC3B,WIPF1,LRP8,CERS6" Coexpression M5185 Genes up-regulated in comparison of dendritic cells (DC) exposed to 50 worm/well B. malayi versus macrophages exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADORA3,AP1B1,BCAR3,ANXA7,ATP2B1,CH25H,SLC4A7,RCHY1,NCOR2,ABCG1,MICAL2,ACOT8,EPB41,BRD8,GRIN2C,HLF,TLX1,RBPJ,KIF5C,KLC1,LMO2,MBNL1,MDM4,PCSK5,PLCB2,PLEC,PMP22,PPM1B,SLC25A36,SATB1,ATXN1,SEC14L1,ST6GAL1,RAB3GAP1,PALLD,SPTAN1,MTCL1,WSCD1,TCF12,AHCYL2,BEX4,TNR,TPM1,TPM4,TUBA1A" Coexpression M8328 Genes up-regulated in naïve CD4 [GeneID=920] Tcells versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD3,PLA2G6,BIN1,RGS9,CDC25B,CDH2,DLGAP1,CHI3L2,ASIC3,SEC31B,SIRPA,SNAP91,DMPK,OPTN,SORBS3,TNK2,MRNIP,RASGRP2,SPEG,TRAF3IP2,STMN2,CIT,PADI2,IL11RA,ADAM11,MMP16,NUMA1,PLCD1,MINDY2,MAPK3,PSD,PTX3,RPS20,SCN7A,RASA3,IZUMO4,CDK19,FCHO1,FAM168A,MCF2L,RPGRIP1L,SYNE1,ZKSCAN5,TUBB2A,TUBA1A" Coexpression M9169 Genes up-regulated in CD4 [GeneID=920] T conv over-expressing: IKZF4 and LEF1 [GeneID=64375;52276] versus GATA1 and SATB1 [GeneID=6304] versus GATA1 and SATB1 [GeneID=6304;2623]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ABHD6,CC2D2A,ARHGAP20,C6orf89,BBS2,CFAP410,CA8,CACNA1A,CAST,HIP1R,CD86,CLIP3,LRIG1,GREB1,DCAF8,RIMS3,CD99L2,ENO2,GPHN,NRN1,FOXO3,EFCAB2,STARD10,RBPJ,RTL5,ZNF862,SSH1,PLCL1,SMOX,PURG,GTDC1,ATXN1,FAM214B,SLC12A4,ABTB1,MCF2L,TEX15,DNAH7,TIAM1,TNFRSF1B,WBP2,TOM1L2,NDRG4,PMEPA1,PHTF2" Coexpression M7746 Genes up-regulated in macrophages with NR3C2 [GeneID=4306] knockout: untreated versus corticosterone [PubChem=5839]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,ARRB1,ALDH4A1,RAB29,CAMK2G,DCAF8,DCTN1,CD99L2,TOM1,BSCL2,EZH1,TAOK3,FOXO3,DHRS4,KDM2B,POLL,GNAS,IL6R,MBNL1,MSRA,MXI1,P2RX7,PURG,PTPA,PRKACB,DEF8,SNRK,ZDHHC4,FBXW7,FAM192A,SEC14L1,ASRGL1,ZFP30,FBXO11,CLSTN1,ANKRD28,PJA1,TF,TNS1,TTC3,TUBB2A,RTN4,JMJD1C,ADAMTS10,FRMD6" Coexpression M7350 Genes down-regulated in HMC-1 (mast leukemia) cells: incubated with the peptide ALL1 versus stimulated with T cell membranes. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "NDRG2,ERMN,SORCS2,GOLGA7B,ATP1A3,CACNA1B,FAM189A2,WHRN,ELMO1,ZC3H11A,SV2B,HS3ST2,ACOT8,DRP2,DSCAM,ELAVL4,MFSD10,FGFR3,TRMO,TMEM151A,GABRB1,GHR,CIT,NXPH3,GPR45,LRRCC1,LIX1,KCNH1,MARK1,LDLRAD3,NPY,FSD1,HYDIN,ZIK1,RGS7,RGS12,CARF,SLC2A5,ARHGAP26,SYT11,ARHGEF9,ASXL3,SF1,ADAMTS10,NETO1" Coexpression M9600 Genes up-regulated in T conv: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,ACTN2,CDC7,TBC1D14,CNIH2,NAE1,CD86,NIPBL,COL9A2,CS,RCAN1,SRPK3,ACSL4,FDFT1,COQ5,DPYSL4,SRCAP,GSN,KIF3A,GUCY1B1,FAAP20,ITGAV,MAP4,MT3,MYCN,MYH6,PC,PKN2,SNRK,PTPRB,PTPRN,UEVLD,SCP2,KIF16B,FHOD3,SMTN,USP33,SPTAN1,MPRIP,FBXW11,TCF12,DICER1,WNK1,NELFE,SNX14" Coexpression M7016 Genes down-regulated in lymphoid-primed multipotent progenitors versus pro-B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "SYS1,RNF157,TXNDC16,ALS2,SFMBT2,NCOA1,GPR146,OSGIN2,RAB29,AKAP12,RNF14,CS,GPSM1,CHRDL1,VPS26C,FGF11,ATP2C1,TRAF3IP2,STARD3,JAK2,KIF2A,TTYH2,CD200,MRPL42,PDE4B,C11orf49,ATG16L1,OXR1,RGR,NCBP3,PUF60,SGK1,FAM102A,DZIP1,FAM214B,ZFP1,ARC,CD27-AS1,R3HDM1,C9orf85,ZNF346,PDSS1,AMACR,FTSJ1,FRMD6" Coexpression M5751 Genes up-regulated in comparison of regulatory T cells versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "NCKAP5,ALAD,BID,MTMR3,CD81,ZBED5,SOCS5,LONRF1,ARMCX4,CD99L2,ARRDC4,EBI3,NRN1,POLK,SPECC1,NEU3,KIAA1958,IRF8,VWA5A,MATK,MATN2,PPM1L,ZNF862,NUCB2,PENK,PLCL1,UHRF1BP1,PLEKHB2,WLS,ANKRD6,FAM214B,GKAP1,KIF13A,C3orf70,AHCYL2,DNAH7,TIAM1,TNFRSF1B,ELP5,CLDND1,PMEPA1,PPP1R3F,ITM2C,PHTF2,ACTR3B" Coexpression M9348 Genes up-regulated in marginal zone B lymphocytes with knockout of BCL6 [GeneID=604]: heterozygous versus homozygous. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "TMCC3,PNMA8B,PI16,APLP1,LGR5,ATP1A3,ATP2B2,CFLAR,CCKBR,NRXN2,TMEM184B,CNR1,PLCH2,BOC,DNAL1,SV2B,DYNC1I1,ANKRD13B,CDKL3,TLR7,PRELID3A,ADAMTS6,HAS2,GPR45,INSM1,C2CD4C,MTTP,MDGA1,PCSK1,PCDH18,SDK2,IRX1,PTPRZ1,CNKSR2,ST8SIA1,LIMS2,MYCBP2,PCDHB7,SYNPO2,FRRS1L,TOM1L2,ANKS1B,PLPPR5,AMN1,TMEM63C" Coexpression M5599 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with IL1B [GeneID=3553] and IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "USP31,AMPD2,ATP1A1,BLM,KRIT1,AP4M1,FOXN3,FADS2,ANKRD44,IPCEF1,SOCS5,PPP1R16B,COPS7A,RBM12,RCSD1,TESK2,POLR1B,NSG1,STAG2,GAP43,STON1,GPR34,HMGCR,SCIN,NCOA7,MAT2A,MID1,NTRK3,PENK,FAM98B,ABCB1,PIK3R1,CDIP1,PACSIN1,MINDY2,PPM1B,PIGG,ATP8B4,DOCK10,ANKRD6,TNIK,BEX1,LARP4,ZNF213,PHTF2" Coexpression M3831 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "DPF1,PLEKHG5,APAF1,SFMBT2,CHID1,ATP2B2,CH25H,CD81,CRMP1,RPS6KL1,DSCAM,DTNB,E2F5,EDN1,EBI3,IGSF6,RCSD1,EFEMP1,FGF11,ATP6V1H,NSG2,AP4B1,GAD1,NR3C1,HSP90AA1,KCNK1,MAP2,MGAT3,NKX2-2,GPR85,PIK3R1,PROX1,PTPRG,RPS6KA2,TNFRSF19,PUF60,SLC12A4,SYT4,TBL1X,TIE1,ICAM5,PLPPR2,NPDC1,SHD,SOCS4" Coexpression M6480 Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS (3h). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "RBM10,C1QTNF1,AMPD3,RIPK1,LRBA,HECTD1,AKAP12,CRY2,ARHGEF10,MAML1,TSPAN5,EDN1,FEM1B,TMEM35A,RPS6KC1,AMOTL2,GPR153,DKK3,CAB39,GHR,RAPGEF1,MUM1,RASSF8,HAS2,SYNPO,ITGAV,LIFR,MX1,NCAM1,PDGFRA,PENK,MED1,KLK6,PTCH1,OXR1,ZNF532,FNDC3A,ZNF334,SLC14A1,SOX2,UNC5B,ZFP90,TRIM2,PSD3,FRMD6" Coexpression M3964 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "GALNT16,DSCAML1,APAF1,DDO,CFLAR,OSGIN2,LHX2,HEPH,PLPPR4,FAM107B,SLC29A4,EDN1,FEM1B,EFNA2,EBI3,NSG2,GABRA3,ARPP21,LOXL3,GRIK3,IL11RA,KTN1,MOV10,NTRK3,PCSK1,GPR85,PROX1,PSD,BCAS3,SLC22A23,PTPRG,LRRK2,IL17RB,FAM81A,PPP4R3A,SLC12A4,CPEB4,SYT1,NSD1,SLC44A1,TIMP4,ICAM5,NPL,TRPS1,FAM181B" Coexpression M5081 Genes down-regulated in comparison of memory CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574] versus naive CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "KLHL13,OSBPL8,MAP4K3,ANXA7,CDK10,OSGIN2,CARS,CCPG1,PLAA,CHD1L,LIN54,DNAJC6,RCAN1,COPS4,C8orf37,APC2,ARMCX1,TESK2,UBE2E3,SMC2,RNPS1,MSL3,AGFG1,HSP90AA1,TUBB2B,SMOX,MAPK9,RPRD1A,ZC3H14,SCAF8,KIF16B,WDR47,ZNF667,RCOR3,ANKRD28,TCF4,KIAA0930,TCF7L2,CRTC1,GPRIN3,TIAM1,ZNF24,EMSY,ST7,HNRNPA3" Coexpression M4659 Genes down-regulated in comparison of naive CD8 T cells versus PD-1 low CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADRB2,EIF4G3,JAZF1,CAST,ADGRG1,CHN2,TMEM184B,TOGARAM2,MICAL2,TOX,JAKMIP2,ZEB2,RABGAP1L,OPTN,STARD3NL,NCALD,KATNAL1,FYN,KIAA1841,RAB40B,ADAP1,GYG1,TTYH2,PIK3AP1,MAP4,MATK,MBP,MYO6,NINJ2,PDE4A,JAKMIP1,PPP2R2B,SYTL2,RALGDS,ZDHHC14,RGS3,PRR5L,ATXN1,RAP1GAP2,SYT11,SYNE2,SLC35G2,TGFBR3,TNFRSF1B,PIK3R5" Coexpression M4507 Genes up-regulated in comparison of stimulated CD4 [GeneID=920] Th1 cells at 12 h versus stimulated CD4 [GeneID=920] Th2 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ANK3,SHTN1,NUMB,AZGP1,ARHGEF2,CDC25B,TMEM184B,C2CD2,APPL1,RIPOR2,DBN1,DNAJC6,ZEB2,DPYSL2,RCAN1,ST8SIA3,TMEM35A,ANKMY1,IP6K2,NBEA,ATP8A2,LPAR4,BACH2,LSAMP,MEST,NBL1,NPTX1,SERPINE2,EPB41L4B,CCDC40,RDX,MAPK12,ASRGL1,SLA,URGCP,RAB3GAP1,BTBD7,KIF21B,STXBP1,CAMTA1,TRPS1,TST,UCHL1,NPDC1,MVB12B" Coexpression M9297 Genes up-regulated in Lung dendritic cell from untreated IL-1R mice versus Lung dendritic cell from Ad5 T424A hexon inf IL-1R mice. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACADM,PLEKHH1,GPR158,LRFN1,CDC42BPA,ANK3,APOC2,DNAH17,N4BP2L1,BBS2,CHGB,CLCN4,TJP2,RAB26,AKAP12,SLITRK5,TBC1D5,CASP8AP2,FAM198B,CINP,GAA,CPLX1,GNAL,DIDO1,TOX2,KCNA1,IL17D,SRSF12,NPR2,OPHN1,PEX2,FEZF2,RGS10,RXRA,DRAXIN,DZIP1,SLC12A2,SSTR1,SYN1,COBL,AKTIP,TSPAN11,NPDC1,ZIC3,ACTR3B" Coexpression M4440 Genes up-regulated in comparison of naive B cells versus blood plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "C1QTNF1,AMT,FAM131A,MTMR9,DDR1,CLCN4,LY86,GPRASP1,ARHGAP32,DCAF8,TBC1D5,KLHL3,ABCC5,SCML2,CORO2B,ANKFY1,GABBR1,CHL1,RAPGEF6,GPM6A,ARHGAP19,IRF8,ITPKB,CD200,ZNF862,PIK3CD,RETREG1,STRN3,POU6F1,MTMR10,RADX,ZNF532,SELL,SLA,INTS9,PEG10,CDK19,TSPYL2,CEP68,TTBK2,SIN3B,TRPS1,VAV2,KAT6A,ACTR3B" Coexpression M7192 Genes up-regulated in transitional B lymphocytes from cord blood: CR2 [GeneID=1380] low versus CR2 [GeneID=1380] high. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "PPFIA4,APP,ARRB1,MYOM1,RAB29,CFAP410,PTBP2,RCBTB2,IPCEF1,CTNND1,COPS7A,CD99L2,DPYSL2,PDCD6IP,STARD3NL,EXTL2,DKK3,GABBR1,SEPT9,KIAA1841,GLS,KDM2B,PADI2,ACOT7,IL6ST,TUBB2B,ITGAV,PTOV1,MYO9A,NUCB1,SLC36A4,BCAS3,PLEKHB2,C1orf54,ARID4A,DGLUCY,CDK5RAP3,ELMO2,DIP2A,TPCN2,USP22,PIK3R5,CLDND1,KCNK12,CERS6" Coexpression M5698 Genes up-regulated in comparsion of sfActCD4 versus sfActCD4TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "C3orf14,AXIN2,OSBPL8,KSR1,MTMR3,LDB2,ENTPD6,CD81,FEZ2,DGKG,PLXNC1,CALCRL,NRN1,STAU2,GSN,GYG1,RBPJ,KTN1,MAP4,LYPLAL1,KCTD6,SFR1,NUCB1,PDE4B,PDE4D,PFKFB4,PLEC,POLG,MAPK4,MTMR10,BSDC1,GTDC1,DGLUCY,EFHD1,UNC80,UHRF1BP1L,NFASC,STOX1,SAMSN1,SEPT8,KIAA0930,ZFP91,TP53BP1,SMUG1,PROCA1" Coexpression M8007 Genes down-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD1,AXIN2,ERMN,CARNS1,ZNF687,RNF182,ARHGEF7,CACNB4,DLGAP1,TJP2,C4orf33,FAM149A,SLC32A1,SRGAP3,ARNT2,SLC9B2,POLK,TDRKH,PRDM5,TMEM25,ZBTB49,ICA1,MAN2A2,NCAM2,NUMA1,TBC1D25,OPCML,EPN1,CDIP1,POU6F1,MAPK3,MAPK7,GDPD2,FIGN,KCTD17,CARF,ROM1,FAM81A,SPHKAP,SLC37A2,KLHL4,TEK,TNFRSF1B,SPHK2,NT5M" Coexpression M4630 Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 3 versus untreated CD25- T cells at day 3. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADORA3,AP2A2,PDXK,ARRB1,BCL7A,LOC730101,DLGAP2,CHN1,LHX2,C2CD2,CREM,CSF2RA,RASSF2,PHYHIP,CNIH3,RHOBTB1,HS3ST2,EBI3,C3orf18,EPB41L2,TUBA1B,CHST15,GATM,STARD3,TDRKH,TUBA1C,GSN,DIPK1A,LAMP2,STMN1,SMAD1,MSRA,OMG,RNASE1,RNH1,STK32B,RXRA,S100B,ANKRD36,MYT1L,GSE1,OBSL1,TK2,BEX4,EVI5" Coexpression M8324 Genes up-regulated in follicular helper T cells: BCL6 [GeneID=604] high versus BCL6 [GeneID=604] low. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD3,CDC42BPA,PLA2G4C,CADPS,NCOA1,BID,TPP1,IFFO1,PPP6R2,USP6NL,CYBB,MATR3,SNAP91,SGSM2,SORBS3,TENM1,EIF1,ST3GAL6,SARAF,SEPT9,SRCAP,STMN2,KAT7,HAS2,PADI2,IL11RA,ITPKB,NUCB2,PDE4B,PLCD1,PLIN1,POU6F1,PYGM,RFX5,PCMTD2,RASA3,CLSTN1,NSFL1C,SYNE2,TRIM2,TPM2,TSN,TUBB2A,PRDM2,TUBA1A" Coexpression M5171 Genes down-regulated in comparison of macrophages versus macrophages exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADCYAP1R1,ARSF,ATP2A2,LETMD1,SUSD5,SOCS5,DGCR5,DMTF1,DTNB,EDNRB,PHC2,OPTN,ELAVL2,DLC1,STAG2,USP19,COPS8,FERMT2,GRIK5,IRAK3,HPS5,C2orf72,INPP5B,KCNF1,KCNK1,MAT2A,MKLN1,PRKACB,PKN2,PRPH,PYGM,QDPR,RAP1GDS1,SCAF8,MAPKBP1,IQSEC2,RAP1GAP2,STAU1,TCF4,FRYL,TNR,ZNF189,SLC30A4,RTN4,CERS6" Coexpression M9410 Genes up-regulated in NK cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "CDC7,MRTFA,APBB2,GAS7,ADAM23,BARD1,BCL7A,BLM,BTK,WASF1,CD38,CDC25B,DZIP3,HDAC9,GSDME,RHOBTB1,DLG3,RASGRP1,TUBB4A,CAMSAP1,FOXM1,GPM6A,GRK4,GUCY1B1,ARHGAP19,NRGN,DPY19L2P2,PKIA,PEX2,ERI2,RGS4,SLC15A2,ZCCHC24,SPP1,SYNE2,ARHGEF9,TACC1,MTCL1,SYNE1,ITGB3BP,TJP1,TMPO,TRIM9,SLC30A3,PHTF2" Coexpression M3733 Genes up-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "TBC1D14,ALAD,ABCD2,NCOA1,CCAR2,BACH1,CCKBR,SOCS6,SLC4A8,IFFO1,ENTPD4,PITPNC1,FBXO25,G3BP2,ACOT8,GNE,SLC37A3,DCTN2,ERGIC3,SALL3,ERAP1,SRCAP,SESN1,ZNF276,INSM2,DIDO1,CLASRP,SYNPO,FAAP20,NAP1L2,ZNF426,EPDR1,RAD17,ZYG11B,ZNF532,ZFP1,TEX2,CLASP2,TAF6,ZMAT3,MTCH1,MICAL1,ZBTB14,C12orf4,UBE3B" Coexpression M3526 Genes up-regulated in comparison of naive CD8 T cells from ELF4 [GeneID=2000] defficient mice versus activated CD8 T cells from ELF4 [GeneID=2000] defficient animals. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "PLEKHG5,SNX30,PTCHD1,USP28,PRMT9,DIRAS1,USP2,CLCN4,CLTB,CRYBB1,PHF14,DCAF4,IP6K1,DCTN1,ACOT8,LPAR6,PLEKHA1,MRNIP,NSRP1,DPYSL4,PDLIM5,USP21,MEGF11,CNTRL,CLASRP,IL6ST,PLCB2,SLC26A11,MTMR10,RALGDS,RXRG,SAFB,PPP4R3A,TNIK,SOX5,AJAP1,ABCC8,TBL1X,TCF4,TF,METTL3,OSBP2,EMX2OS,MEIS3,DOCK8" Coexpression M4351 Genes up-regulated in comparson of lung tissue from wild type mice subjected to ozone for 6 h vs that from TLR4 [GeneID=7099] deficient animal subjected to ozone for 6 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "TMCC3,ADD3,SLC12A5,SORCS1,SRPX,ABCD2,NCOA1,ATP1B3,CDK5R1,OSGIN2,CERS5,CHGA,SDC3,CYBB,MYEF2,RCAN1,EDNRB,PLXNC1,EPB41L2,TUBB4A,SUCO,PCYOX1,NOP56,JKAMP,SARAF,GHDC,HMGCR,KCNJ4,KCNJ5,KCNJ11,SMAD1,PIK3AP1,MRPL42,SNX10,PMP22,STRN3,EXOSC10,PRKAR1B,PRPSAP2,APTX,ROBO1,LRRK2,PKNOX2,STAU1,CFAP298" Coexpression M6671 Genes down-regulated in bone marrow-derived macrophagesat 180 min of stimulation by IL10 [GeneID=3486] and LPS: IL6 [GeneID=3469] knockout versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,ADD3,ABCD2,ALK,MTMR7,TENM4,SIPA1L1,PDE4DIP,CNTNAP2,DGKG,DMTF1,MAMLD1,EDIL3,BSCL2,C8orf37,USPL1,ENPP6,GALNT15,ATP8A2,GFRA2,FICD,MAP4K5,RASSF8,HSPA1L,ITGAM,MEF2C,LAYN,PFKP,SH3KBP1,APTX,PTK2,DPF2,MAP6D1,FNDC3A,LGI3,MCF2L,WWC1,TGFBR3,THRA,TCEAL7,AMZ1,TMEM198,SPIRE1,SLC30A4,ST7" Coexpression M6842 Genes up-regulated in CD4 [GeneID=920] T cells from lymph nodes: naïve versus day 28 after immunization. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "OSBPL8,NUMB,ATM,KRIT1,CD86,RCBTB2,NRXN3,CLCN3,KIAA1549L,QKI,CREM,CSF1R,ERC2,DCC,FBXL5,CEP170,DDX46,USH1C,RRAGB,CHST15,FKTN,NPTN,PNMA2,TBR1,ZMYND11,HNMT,IGF1,RBPJ,NELL1,DDR2,PC,SMOX,PTCH1,SEC14L1,ITSN1,PALLD,SST,FAM168A,DNAJC9,MTCL1,TRIM2,DICER1,SSBP2,FLRT2,GJC2" Coexpression M3076 Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy CD19 [GeneID=920] B cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "TKTL1,APBA2,ARNTL,ARRB1,ATP1A1,CALM1,CAMK2G,RAB33A,LRIG1,MICAL2,IPCEF1,HDAC4,AK5,RASGRP1,OPTN,LPAR6,GOLGA7,NCALD,VPS26C,FHL1,SEMA4D,FYB1,FYN,IL11RA,ITPKB,NELL2,PDE3B,PDE4D,PIK3R1,CCSER2,PLCL1,PRKACB,PTPN13,RGS10,RIC8B,FAM102A,TNIK,CLUAP1,STXBP1,DOCK9,TGFBR3,AKTIP,TIAM1,NACC2,ATP6V0E2" Coexpression M4111 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "OGT,BCHE,NRP2,CAMK2D,SEPT7,MS4A7,CNOT8,HECTD1,CP,UBXN2A,BOC,MYEF2,WDR20,DTNB,RASGRP1,CALCRL,EXTL1,REEP2,PHYHIPL,FAM184B,GFER,GK,GRIA4,GABARAPL2,HP,ITGAV,JAK2,OLFM3,SMAD1,MITF,GPR85,PFKP,EXOSC10,PXK,PTPRB,PPP2R3C,SLC1A3,FAM214B,SYPL1,TBCEL,ACSL6,WBP2,UBE3A,FRMD6,SPATA13" Coexpression M9443 Genes down-regulated in splenocytes: control versus infected with Sendai virus. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "TAOK1,OGT,TNRC6C,EIF4G3,STX16,KMT2C,NCOR1,PITPNC1,SEC16A,DMTF1,LPAR6,TNK2,EPB41,ST3GAL6,KIAA1109,GABBR1,IQGAP2,SPIN1,PRRC2B,L1CAM,MBP,MID1,NFIA,PDE1B,PIK3CD,EPN1,PRKACB,NDUFS7,CASTOR1,RAB3A,CLIP1,SCP2,RUFY2,KIF21B,SP4,CAMTA2,PRRC2C,ZFR2,TK2,PRRT1,HIRA,UBTF,ZBTB14,ZIC3,SLC38A1" Coexpression M5769 Genes up-regulated in IL7R [GeneID=3575] low effector CD8 T cells versus IL7R [GeneID=3575] high effector CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "DGCR6,AS3MT,GALNT16,TEX22,OSBPL8,KCNT1,RASL11B,BAIAP3,CACNA1D,COG1,OSBPL3,USP6NL,CX3CR1,MYADM,ZEB2,TSPAN5,LRRC17,RASGRP2,STX2,SH3YL1,BAIAP2,PRKAG2,ADGRA1,NCKAP1,MSL3,GPD2,MAN1B1,TUBB2B,OLFM3,L1CAM,MTTP,PLEC,EPN1,SYTL2,PTH1R,SEC14L1,SMTN,CDK19,RAP1GAP2,TAF6,ATP13A2,EML6,LRP8,TMEM163,SPATA13" Coexpression M8220 Genes down-regulated in Pmel-1 CD8 T cells: naïve versus primed with cognate antigen (gp100) and IL2 [GeneID=3558]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACHE,SLC25A25,LTBP4,PROM1,DDR1,CALB1,CALB2,CH25H,USP2,ENTPD2,CNN3,PREPL,DLG3,EDN1,ELN,ENO2,SEZ6,SH3YL1,FHL1,NCKAP1,HP,IL12A,MEIS1,CCDC80,MTTP,MYCN,PENK,PMP22,SEPT4,SEC61A2,MYH14,BTBD3,KDM3A,ST5,SYT11,ABCC8,ZFR2,RHBDL3,TEK,HEY1,BEX4,TRO,AMOT,NAV2,FZD3" Coexpression M7441 Genes down-regulated in CD4 [GeneID=920] T cells: medium versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ARID1A,TAOK1,ALDH4A1,BBS2,GPR146,CAMK2G,NIPBL,RBM39,ABCG1,SIPA1L1,PITPNC1,RASGRP1,PHF20L1,BSCL2,ATP8A1,EVL,SPIN1,OS9,MAP4K5,MUM1,IL6R,INPP5B,ITPKB,L1CAM,CHIC1,MIA2,SESN3,IDNK,PDE4B,RAP1GDS1,ATP8B4,WLS,SBF1,FAM102A,SLC14A1,KIF21B,SP4,CAMTA1,TCF7,SYNE1,ARHGAP9,LRRC8A,SGK3,PARP6,KLHDC1" Coexpression M8098 Genes up-regulated in speen B lymphocytes: marginal zone versus follicular. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "SLITRK1,SLC24A4,SNX32,DOC2A,ARNTL,PDE8B,BRSK2,DLGAP1,ZFYVE9,SEC24C,DBT,GSDME,DLG3,CASP8AP2,EPS8,FABP7,PDLIM5,ATP6V1H,FYB1,DENND2A,AHCYL1,SPIN1,HMX1,MAP6,CD200,MDGA1,TBC1D25,PFKFB4,SMIM7,MTMR10,PTHLH,ZNF532,TMEM206,RPS6KA2,HES6,IL17RB,GKAP1,KIF13A,SON,MYT1L,CDK20,MICAL1,AMZ1,WIPF2,HNRNPA3" Coexpression M9293 Genes up-regulated in Lung dendritic cell from untreated wildtype mice versus Lung dendritic cell from Ad5 T424A hexon infection wildtype mice. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "PKP4,ARHGAP5,ZNF583,CFAP410,AKAP6,BTF3L4,ABCG1,PPP1R16B,DGKG,DNAL1,RAB39B,REEP2,AMZ2,CORO2B,C2orf88,GAA,USP19,GNAO1,GRIK4,ITGA7,JAK2,KIF5C,MYH3,NFE2L2,NTRK3,SETD4,TMIE,MTMR10,CARF,CNKSR2,DZIP1,ZNF365,KDM4D,KIF13A,USP33,TCF7L2,TK2,CDK20,ZNF346,TSC1,CLHC1,UBE3A,TOM1L2,CLIP2,MEIS3" Coexpression M9288 Genes down-regulated in Lung dendritic cell from Ad5 infection wildtype mice versus Lung dendritic cell from Ad5 inf IL-1R mice. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ACTN1,SEMA7A,USP28,EPB41L5,SFMBT2,ARHGAP5,GPR146,SLC25A14,CD81,LRIG1,USP6NL,RIPOR2,TOX,DNAJC6,TRAPPC9,EGR3,KCNMB4,GPM6B,TOX2,AGFG1,IL6ST,IBA57,ITGA7,KCNC2,MATK,CD200,MYO6,NME4,NUCB2,P2RX7,PDE4B,PACSIN1,PRKCB,RGS10,ST6GAL1,CABCOCO1,ZC4H2,ZFR2,TCF7,TGFBR3,TPD52,RUNDC3B,ZNF24,LYPD6,CERS6" Coexpression M3229 Genes up-regulated in regulatory T cell (Treg) versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ABHD6,EMILIN3,ADCY5,ZNF608,SORCS2,RGS20,CACNA1B,CABP7,ARHGEF25,EVI5L,CNTFR,CSF1,LRIG1,RUSC2,AK5,DLG3,C3orf18,EPB41L1,GABRG2,RAPGEF6,SYT17,PRDM5,ACOT7,IGF1,DOCK7,KCNQ2,TTYH2,KITLG,MYO6,RCOR2,NFIX,NPR2,OPRL1,CDK18,FXYD1,SGSM1,SMPD3,MYO16,ZSCAN29,VAMP1,ASTN2,PRMT8,TRPC3,CELF4,FRMD6" Coexpression M6021 Genes down-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by IL4 [GeneID=3565] (6h). MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "SDE2,ADD3,SNX30,TXNDC16,BCAR3,TMEFF1,NCOA1,BCL7A,BID,OSGIN2,MAP7,ARHGAP33,PCYT1B,AHCTF1,GAPVD1,LONRF1,DTNB,DNM1L,HIPK3,STAG2,IDH3B,ITGAV,JAK2,IPO5,LIFR,MBP,SH3KBP1,PXK,RAP1GDS1,REV3L,ZC3H14,SLC9A5,SULF2,C3orf70,TBCEL,IQCE,C18orf54,ITGB3BP,TK2,ACTR6,TPD52,ZNF346,USP1,WIPF1,PPP1R3F" Coexpression M6201 Genes down-regulated in polymorphonuclear leukocytes (24h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "CPNE2,OSBPL1A,ALAD,CACHD1,CA12,NMT2,ARMC8,AKAP5,ABCC9,SUGP2,KATNAL1,EFEMP1,SCARA3,FOXG1,TMEM107,GAB1,C15orf41,CRCP,GLI2,CIT,SCRT2,MID1,CD200,NRCAM,PENK,UHRF1BP1,PTPN13,ZDHHC14,RGS12,LGI2,CCDC25,ATAT1,YJEFN3,URGCP,SLC20A2,ARFGAP1,KIF1B,STXBP1,SEMA4A,VWCE,TIAM1,TRPC1,REEP1,PRDM10,VANGL2" Coexpression M3178 Genes up-regulated in comparison of naive B cells versus memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "AP1B1,PKP4,MAGEE2,DGKD,MARCH3,ZSCAN18,ZBTB10,ATP6V0A1,CAMK2D,CLIP3,ARHGEF10,KIAA0040,MYADM,KBTBD11,DPP6,EDN1,PLEKHA1,CEP85L,FDFT1,RAPGEF6,MSTN,GK,PLCD4,BACH2,ZNF667-AS1,TM6SF1,AFF1,CD200,PCDH9,ABCB1,DEF8,PTPRE,RFX4,SATB1,SH3BP2,SLITRK3,SLA,LIMS2,SLC8A2,SCN3B,MCF2L,HIF3A,RP9P,DDHD1,SLC38A1" Coexpression M8306 Genes down-regulated in activated T cells: CD4 [GeneID=920] versus Va24- NKT. MSigDB C7: Immunologic Signatures (v6.0) 5.56E-03 1.00E+00 3.43E-02 3.41E-01 45 200 "ADD3,CALM1,CDC25B,FOXN3,TPP1,IFFO1,RBM39,PPP6R2,SPOCK2,SGSM2,DNAJB6,EIF4G2,EIF5,TENM1,TNK2,EIF1,VPS13B,RASGRP2,SH3YL1,ST3GAL6,SARAF,FYB1,SRCAP,KAT7,IL11RA,ITPKB,MBNL1,NUCB2,PAX6,PDE4B,PDE4D,HERC2P3,SNRK,PCMTD2,RPL38,SYNE2,MCF2L,TCF7,SYNE1,TSN,TUBB2A,PRDM2,TUBA1A,CIAPIN1,MPPE1" Coexpression 18435859-ShorterGeneList Mouse Breast_Piechocki08_558genes GeneSigDB 5.59E-03 1.00E+00 3.45E-02 3.43E-01 77 376 "ACTN1,NDRG2,ABCD2,GAS7,TMEFF1,NRP2,BMPR1B,SGCE,CD38,CDH2,CDH10,JAM2,ABCG2,CNTFR,ABCG1,CSF1,TENM4,VCAN,CTNND2,SPOCK2,SACS,ABCC5,EGFR,MBNL2,CERCAM,CDHR1,HSPA12B,EFEMP1,FGF1,CSPG5,DKK3,CHL1,IGSF5,TUBA8,GHR,GJB1,ADAMTS8,GSN,IRAK3,HAS2,HSD17B1,IL6ST,ITGA7,LAMA2,MAPT,MATN2,MATN3,MID1,MMP16,MYO9A,NCAM1,PDGFRA,SERPINI1,PCDHB17P,PPP2R2B,MASP1,KLK6,TNFRSF19,ABLIM3,MAST1,PCDHGA11,PCDHB7,PCDHB3,TNS2,CHST8,TNS1,TPM2,TRO,TMEFF2,FLRT2,MICAL1,WNT7A,TUBA1A,ADAMTS9,FZD3,NETO1,CBLN2" Coexpression 15297395-SuppTable2 Human Lymphoma_Sriuranpong04_373genes GeneSigDB 5.60E-03 1.00E+00 3.46E-02 3.43E-01 59 276 "AXIN2,BRAP,NME5,OSBPL6,CEP126,DDO,CDK10,PDE8B,NUMB,MPDZ,CAPN3,CAST,CLDN10,CLU,CP,RHOBTB1,DNAH9,TOM1,BSCL2,EML1,LRRC23,EPS8,EZH1,F3,CACNG3,CAP2,TRIM16,GALC,BRD8,ITGA7,STMN1,LMO2,VWA5A,MEIS1,MID1,MITF,NUCB2,OXTR,PRKCZ,SYTL2,PTPRZ1,RFX2,RFX3,ROM1,ASRGL1,SLC22A4,SMARCD3,ATP10B,TRIM2,TF,TGFBR3,ZFP91,TMPO,TP53BP1,TPM4,NEIL2,ZBTB14,MEIS3,DNALI1" Coexpression M466 Genes up-regulated in NIH3T3 cells (fibroblast): control versus stimulated with IFN-b. MSigDB C7: Immunologic Signatures (v6.0) 5.60E-03 1.00E+00 3.46E-02 3.43E-01 33 137 "AXIN2,PCDH19,LRRC7,APP,RGS9,CDO1,CHGB,PDE4DIP,FRMPD4,SNX29,ATL1,CD320,FECH,FGF13,RAPGEF1,AQP11,NCAM2,PRKAB2,KCNIP2,CDK5RAP2,WDTC1,TRERF1,SP2,DIP2A,ZC3H4,CNTN2,ATMIN,SLC35G2,ATP13A2,RGMB,UBTF,TRIM9,MVB12B" Coexpression M2521 Loci bound by both isoforms (a and b) of SALL4 [GeneID=57167] in ES cells (embryonic stem). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.62E-03 1.00E+00 3.47E-02 3.44E-01 50 227 "PLEKHG5,ZNF608,NR0B1,OGT,TMEFF1,RGS20,INSYN2B,SRSF11,B4GALT6,JAM2,MAP4K4,AKAP12,CST3,MATR3,SMG7,SEC16A,KLHL5,LPAR6,ETV1,EYA1,FGFR1,SYNCRIP,C2orf88,GCNT2,KDM2B,GPM6A,ZIC5,IL6ST,KIFC3,STMN1,MYCN,NKX2-2,NPTX2,ETFRF1,PDE1A,PDPK1,ZDHHC14,MSANTD2,ZNF532,SOX2,SULF2,FGD4,COBL,TRIM2,FRYL,SLC44A1,TP53BP1,TPD52,PARP6,FBXO36" Coexpression M2208 Potential targets of MIR302A [GeneID=407028]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.67E-03 1.00E+00 3.49E-02 3.47E-01 21 77 "JAZF1,ZNF385A,CLOCK,E2F5,EFNB3,EIF4G2,FOXG1,HLF,MYT1,NEUROD1,ARID4A,RBBP6,RIC8B,ZFHX4,RORB,SLITRK3,SOX11,ZFPM2,VLDLR,KAT6A,PHTF2" Coexpression 12011421-Figure3 Human Lymphoma_Tibshirani02_43genes GeneSigDB 5.69E-03 1.00E+00 3.50E-02 3.48E-01 13 40 "ALDH7A1,CDH2,FCGRT,FDFT1,OLFM1,GAP43,GATM,MEST,MN1,PBX1,PTPN13,TNNT1,FNDC5" Coexpression M448 "Genes down-regulated in control CD4 [GeneID=920] T cells versus those infected with HIV-1 viruses lacking Env, Vpr and Nef." MSigDB C7: Immunologic Signatures (v6.0) 5.70E-03 1.00E+00 3.51E-02 3.49E-01 32 132 "CPNE2,ABCF1,ADCY8,APBA2,MAGED1,DLX1,EGFR,ANKRD13B,GFAP,GNAL,PTPN5,SYNPO,KLRC2,PIK3AP1,SERPINE2,ANLN,PSD,DUSP15,RGS12,CCDC112,CLSTN1,CXXC4,GKAP1,SPATA7,TSNAXIP1,BEX1,DDN,ATP10B,THSD1,SEZ6L,PRR18,NETO1" Coexpression M2230 Genes bound by ESR1 [GeneID=2099] and up-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.71E-03 1.00E+00 3.51E-02 3.49E-01 47 211 "GPRIN1,PLEKHH1,UNC5A,AP1B1,CDK5R1,CA12,LONRF2,AHCTF1,NCOR2,LRIG1,RIMS4,GREB1,MED24,CCDC3,E2F6,POLR1B,ACSS1,MFSD2A,TUBB2B,KHK,LMO1,SYTL4,MAG,MAT2A,SMOX,TMEM104,PTH1R,RAB3IL1,RET,MORC4,SYNDIG1,SOX8,FAM102A,CHD9,SYBU,KDM4B,SOX3,KAZN,CAMTA1,WWC1,SIN3B,CHST8,TIAM1,NEIL2,REEP1,AMZ1,SEMA3B" Coexpression M2820 Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL2 [Gene ID=3558]. MSigDB C6: Oncogenic Signatures (v6.0) 5.74E-03 1.00E+00 3.53E-02 3.51E-01 44 195 "ASPHD1,KDM5D,ABCD2,PLA2G4C,PROM1,CACNA1E,CBLN1,CHGB,ERC2,SNPH,MAGI2,RHOBTB1,ARNT2,ZNF391,RASL12,EYA1,CACNG3,FUT9,CYP46A1,SESN1,GUCY1A2,TAGLN3,NAP1L2,PAK3,PBX1,PCSK5,PDE1C,PLCD1,PLCL1,SCHIP1,PPP2R5C,KLHDC8A,RORB,SEMA6D,SCN3A,HKDC1,SLA,SLN,NACAD,SYT1,CUX2,TEK,FZD3,CAMK1G" Coexpression M8939 Genes up-regulated in visceral adipose tissue of aged mice: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 5.79E-03 1.00E+00 3.56E-02 3.53E-01 31 127 "ALK,PI16,MYH7B,AQP4,ASGR1,ADGRB1,CAMK2A,ARHGAP22,COL4A5,GAL3ST1,SLITRK5,CTNND2,DTNA,GAP43,DNER,CNDP1,GRM5,TOX2,HRH3,MOBP,NEFM,NHLH1,RAB3IL1,ROBO2,BCAN,OGDHL,ABCC8,ROBO3,TNR,TRPM2,TSPAN11" Coexpression 17409455-TableS3 Human Breast_Winter07_67genes GeneSigDB 5.80E-03 1.00E+00 3.56E-02 3.54E-01 15 49 "ZSCAN18,ATM,ARHGEF6,ANKRD44,RIPOR2,DOCK2,TLR7,ATP8A1,IRF8,LMO2,ENPP2,ABCB1,SYNE1,SYNPO2,KLHDC1" Coexpression M8238 Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype untreated versus RORC [GeneID=6097] knockout treated by digoxin [PubChem=2724385]. MSigDB C7: Immunologic Signatures (v6.0) 5.88E-03 1.00E+00 3.61E-02 3.58E-01 40 174 "ACTN2,ADORA2A,PDZD4,AMPD2,CDC14B,ZFYVE28,NUMB,B3GALT2,N4BP2L1,DPY19L3,BCL2L2,ACY3,ABI1,ARRDC4,RASA4,RASGRP2,STX2,RTN3,AGAP2,GFRA1,LYVE1,GRK4,HPSE2,LIG4,GPR155,MATK,PPM1L,PCSK1,JAKMIP1,PPP3CA,PRKACB,PRODH,RNASEL,PPM1E,ST6GAL1,SLA,USP33,ZCCHC24,PLD4,CERS6" Coexpression M371 Genes down-regulated in macrophages: 5 days with IL4 [GeneID=3565] and dexamethasone [PubChem=5743] followed by TGFB1 [GeneID=7040] for 24h versus 5 days with IL4 [GeneID=3565] followed by TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 5.88E-03 1.00E+00 3.61E-02 3.58E-01 40 174 "ADORA2A,HACE1,INSYN2B,RIPK1,CFLAR,SYNJ1,SLC25A14,KRIT1,MS4A7,OSBPL3,TMEM170A,HP1BP3,FBXO25,ZC3H11A,RABGAP1L,SIDT2,KMT5B,DCTN4,POLK,ZMYND11,GNAL,COQ10A,ITGAM,ITPKB,MBP,PLCB2,PRKACB,BCAS3,CEP97,EPC1,LMBRD1,TNIK,RAP1GAP2,TBCEL,WDR7,CYB561A3,RNF103,MPPE1,ZDHHC20,SNX14" Coexpression M1275 Cluster PAM2: genes up-regulated in hepatocellular carcinoma (HCC) vs normal liver tissue from mice deficient for TXNIP [GeneID=10628]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.89E-03 1.00E+00 3.61E-02 3.59E-01 36 153 "KIAA1324,ABCD2,APP,DYNLL1,BMP7,DDR1,FMNL3,ADGRG1,RAB3C,B4GALT6,MAP4K4,MYADM,SIRPA,HEPH,GSDME,DLG4,ABCC5,ACSL4,TUBA8,LYVE1,PSRC1,DDX25,NAP1L1,PFKFB3,ABCB1,PTPRE,ROGDI,ERI2,MORC4,RTKN,SCN8A,SLC12A4,TPM1,TUBB2A,NPDC1,ZFP37" Coexpression M1963 Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MEF cells (embryonic fibroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.91E-03 1.00E+00 3.62E-02 3.60E-01 46 206 "SLITRK1,AQP6,PDE8B,C5,FAM149A,NCAN,PLCXD3,KIAA0408,PHYHIP,ELMO1,DLG2,SEZ6L2,LRRC23,KCNMB2,ANKMY1,ZIC4,FGR,SYT3,NSG2,GRM3,ATCAY,BRINP3,KCND2,KCNJ5,KCNJ9,KCNN3,LRRC4B,FXYD7,ZDHHC22,KCNK10,PDE1C,PDYN,GDAP1L1,PIK3CD,SLC25A41,PNMA8A,KCNIP2,RYR1,SYBU,FAIM2,C11orf87,ANO4,CUX2,ARHGAP9,CA14,TMEM63C" Coexpression M17143 Genes down-regulated in primary granulosa cells after stimulation with LH or FSH gonadotrophic hormones for 24 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.91E-03 1.00E+00 3.62E-02 3.60E-01 23 87 "ACTN1,KIDINS220,ATP2A2,CFLAR,MAP4K4,AKAP12,CTNND1,DAPK1,CAP2,FLNC,HSD17B1,CDK14,PIK3CD,PLCL1,PPP2R5C,PTPRE,RGS4,SMARCA4,TPM1,TPM2,TUBB2A,RPRM,TUBA1A" Coexpression M8132 Genes down-regulated in decidual macrophages with ITGAX [GeneID=3687] high versus low. MSigDB C7: Immunologic Signatures (v6.0) 5.93E-03 1.00E+00 3.63E-02 3.61E-01 43 190 "UNC5A,KIAA1211,LDB2,UBE2L6,COL4A5,CSF1R,DZIP3,NRSN1,HEPH,GUCD1,SEMA3D,CALCRL,TUBD1,ENPP6,ZNF549,SIRPB1,TVP23A,ADAM28,PSRC1,GPR34,KCNA1,CLVS2,KCNJ5,INSYN2,SCAMP5,TCEAL5,NCF2,NEFH,PDE4B,EPN1,PTK2,PTPRD,LRRTM4,SLC8A1,FAM126B,WDTC1,ELOVL4,MLC1,ASXL3,SPHK2,TCEAL7,PCBP4,ACTR3B" Coexpression M19930 Genes up-regulated in B-CLL (B-cell chronic leukemia) samples expressing high levels of LPL [GeneID=4023] compared with those expressing low levels of the gene. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.96E-03 1.00E+00 3.65E-02 3.62E-01 18 63 "BCL7A,SGCE,AKAP12,KIAA0040,ARMCX2,ELMO1,GSDME,DMD,FRY,TLR7,PNMA2,DCLK2,BACH2,DIPK1A,ST6GAL1,PEG10,DNMBP,FBXW11" Coexpression 15701848-Table2 Human Stomach_Yang05_96genes GeneSigDB 5.98E-03 1.00E+00 3.66E-02 3.63E-01 24 92 "STX16,BMP7,CBFA2T2,CDC25B,CST3,PPP1R16B,RASSF2,SIRPA,SPATA2,EDN3,RBM12,SEC23B,SDCBP2,GNAS,IDH3B,KCNB1,PDYN,PLTP,CRLS1,PCMTD2,NSFL1C,PLCB1,ZMYND8,SLC13A3" Coexpression 17660535-TableS7 Mouse InnerEar_Sajan08_109genes GeneSigDB 6.02E-03 1.00E+00 3.68E-02 3.65E-01 25 97 "C1QTNF3,CFLAR,CALB1,CAMK2B,CANX,COL9A2,HAPLN1,DCT,ELAVL3,ELAVL4,TUBB3,EFEMP1,GLDC,GRIA1,SOX21,FRMD5,IGF1,PMP22,PRRX1,MASP1,ZFHX4,ARX,SOX2,RFTN2,SSPN" Coexpression M4508 Genes down-regulated in epidermis after to UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.10E-03 1.00E+00 3.73E-02 3.70E-01 100 508 "ABR,ARID1A,ALAD,BBOX1,APC,ARNTL,NCOA1,EIF4G3,ATP2B1,AZGP1,BCHE,CH25H,SPAG9,PRC1,SCARB1,LRRFIP1,FOXN3,NCOR2,DAPK3,DBI,DNM1,USP3,RCAN1,E2F6,EEF1A2,FEM1B,FRY,EGR3,EML1,EFS,RTN3,F3,TESK2,FHL1,SUCO,SYNCRIP,SEMA4D,TACC2,TRIM16,TPPP3,FYN,DKK3,GALC,GATM,RNPS1,DBF4,RAB40B,GSN,MAP4K5,PACSIN2,HLF,HSF2,IRF8,IL6R,ITGAV,KCNK1,KIT,LSS,MAT2A,MATN2,MSRA,MYO6,NELL2,PDE4B,PFKFB3,PMP22,PPP3CA,PKIA,PRKCB,QDPR,ROBO1,RPS6KA2,ZNF331,SATB1,ATXN7,SLC1A6,SLC6A9,SPTAN1,ITPRID2,ERBIN,STXBP1,ACSBG1,TAF9,TCF4,SIRT1,TGFBR3,KAT6B,TP53BP2,TPD52,TRPS1,TSC2,SSBP2,CADM1,UBE2H,PITPNB,ZBTB16,SH3GLB2,PRDM2,TUBA1A,GAN" Coexpression M9427 Genes down-regulated in wildtype DN3 thymocytes versus T cell lymphoma cells from TCF7 [GeneID=6932] knockout. MSigDB C7: Immunologic Signatures (v6.0) 6.16E-03 1.00E+00 3.76E-02 3.74E-01 34 143 "HFM1,SEMA7A,PHYHD1,AQP6,ZFYVE28,RASL11B,CACNG1,SNCAIP,PHF19,RIMS3,DNAJC6,TMCC2,CD99L2,FSD1L,PTK2B,FCGRT,PNMA2,ABLIM2,HMX1,ITPKB,INSYN2,SNX10,ST8SIA5,PLEC,MDGA2,PTPRD,RNF220,KCNIP2,ABLIM3,SEMA4A,CHST5,ADAMTS10,AAAS,SPATA13" Coexpression M7439 Genes down-regulated in fibroblasts expressing different mutant forms of ERCC3 [GeneID=2071]: XP/CS (xeroderma pigmentosum (XP) and Cockraine's syndrome (CS)) vs TTD (trichothiodystrophy). MSigDB C2: CGP Curated Gene Sets (v6.0) 6.20E-03 1.00E+00 3.78E-02 3.75E-01 12 36 "CLCN4,VCAN,DLC1,STAMBP,HAS2,ENPP2,PRKCZ,PTN,DOK5,CAND2,SSBP2,VLDLR" Coexpression M13327 Genes down-regulated in uterine fibroids with deletions in the 7q region vs those without the deletion. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.20E-03 1.00E+00 3.78E-02 3.75E-01 12 36 "OSBPL1A,APBB2,AKAP6,NCOR1,GAPVD1,ING4,GAA,EML4,IFI16,PDE3B,NEK11,CADM1" Coexpression M18467 Genes expressed in multiple myeloma (MM) patients carrying specific translocations involving the immunoglobulin heavy chain (IGH) locus at 14q32. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.20E-03 1.00E+00 3.78E-02 3.75E-01 12 36 "CX3CR1,CYBB,DPYSL2,KCNMB2,FGFR3,GUCY1A1,IL6R,NTRK2,GALNT10,ATP13A2,TLR4,NSD2" Coexpression M2477 Genes up-regulated hT-RPE cells (immortalized retinal pigment epithelium) by MYC [GeneID=4609]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.22E-03 1.00E+00 3.79E-02 3.76E-01 52 239 "ADD3,ANXA7,BLM,LDLRAD4,CACNB2,LARGE1,PCYT1B,AKAP12,CTH,CTNND1,DNAJB6,ABCC5,E2F5,CELSR3,LRRC17,ATP8A1,NOP56,TACC2,CAMKK2,FYN,DKK3,GAD2,MSTN,MMADHC,GLDC,ATF7,GSN,HSPA1L,IGFBP1,ITGA7,KCNH2,STMN1,MAG,MMP17,MXI1,NBL1,PCDH8,PGAM2,FAM216A,PLEC,WBP1L,PTPRN2,PEX5,QDPR,RAB5B,RAP1GAP,SMTN,KIAA0930,TCF7L2,ZEB1,TP53BP2,ZNF177" Coexpression M2584 "Genes down-regulated in the ventricles of healthy hearts, compared to atria." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.30E-03 1.00E+00 3.84E-02 3.81E-01 56 261 "ACTN2,GRAMD1B,PLA2G4C,ADAM23,AZGP1,AIFM1,MYOM2,CDH2,CHN1,CHN2,TJP2,TCAF1,SRGAP3,RCAN1,ABCC9,HIPK3,RCAN2,EYA1,CAP2,DPYSL4,PDLIM5,GAB1,ALDH1L1,GCNT2,GNAS,GRM1,IDH3B,KIFC3,LAMA2,MAOB,MAP4,MEIS2,MYL3,SETD4,OGDH,OPA1,PDE1C,PDE3A,PFKP,PLCL1,POLR2F,PPP2R5C,PKIA,NDUFS7,SH3GL2,NLGN1,SLC1A3,COA1,LIMCH1,PDZRN3,ZBTB43,PCDHA3,TNNT1,UBE2H,UBE3A,NDRG4" Coexpression M9234 Genes down-regulated in CD8 T cells with STAT1 [GeneID=6772]: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 6.32E-03 1.00E+00 3.84E-02 3.82E-01 44 196 "TNRC6C,APP,TMEM263,JAZF1,CAMK2D,CD38,CLCN4,SLC4A8,SIPA1L1,CTNND1,ARHGAP32,BLOC1S6,SEMA3D,PLEKHA1,CALCRL,EPB41L2,FLT1,HVCN1,SARAF,SYT17,SESN1,RAB30,BACH2,ZNF546,MEF2C,BLOC1S2,ABCB1,SERPINI1,ANKRD16,SNRK,BEND5,TMLHE,SH3BP2,CNKSR2,BTBD3,DHX30,IFT122,ZNF415,ZHX3,SEMA4A,TRPS1,SLC38A1,SNX27,NETO1" Coexpression M8503 Genes up-regulated in untreated B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 6.32E-03 1.00E+00 3.84E-02 3.82E-01 44 196 "ALCAM,CARNS1,MYH7B,SMIM29,ASPH,TRIM41,SLC16A4,NECTIN3,ANKRD44,ARHGAP24,SPOCK2,ABI2,EPB41,CEP85L,CLVS1,KAT8,FYN,TRAF3IP2,ZNF559,GPM6A,PLPP7,MGC16275,SYNPO,NAP1L3,NME4,PCDH8,PENK,PRKCB,ZDHHC14,RIC8B,RPS6KA2,R3HDM2,CCDC92,CLSTN1,UNC80,TCEA1,TRIM2,PCDHAC2,CYB561A3,ZMAT3,TPM1,LINC01268,WNK1,PMEPA1" Coexpression M1970 "Genes with intermediate-CpG-density promoters (ICP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV8.1 cells (induced pluripotent cells, iPS)." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.33E-03 1.00E+00 3.85E-02 3.82E-01 16 54 "ADCY6,CNTNAP1,LRRC4C,NOL4,LSMEM2,CNTNAP2,ZIC4,FGF14,LRRTM3,KCNJ9,FXYD7,ZDHHC22,PDE1C,RFX4,TMEM100,SOX6" Coexpression 16266895-Figure1 Human Leukemia_Heuser05_100genes GeneSigDB 6.33E-03 1.00E+00 3.85E-02 3.82E-01 16 54 "KLHL13,APOC2,ATP2B1,ALDH7A1,PROM1,RASSF2,FGFR1,FHL1,DNER,GJB1,EML4,MBNL1,MN1,NBL1,PTK2,BEX1" Coexpression M9639 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.43E-03 1.00E+00 3.91E-02 3.88E-01 80 395 "MTUS1,EP400,SHROOM2,ARRB1,ADAM15,DST,SYNJ2,CA12,CALB2,LDB2,CDH2,ADGRG1,CLU,NCOR1,EGFR,EPB41,RCAN2,LRRC23,STX2,ERBB2,EFEMP1,ATP8A1,ST3GAL6,FGF13,FHL1,FOXG1,COQ5,TPK1,KHDRBS3,GAA,GAD1,TMEM8B,FAXC,C1QL1,LNX1,GSN,KAT7,FICD,GUCY1B1,TOX2,CPT1C,KLRC2,KLRC3,LSS,MATN2,MYO6,PC,PDE4B,PKIA,PTN,SH3TC2,RADX,RGS4,CCDC25,MCMBP,FAM192A,SATB1,SCG5,MYO18A,ANKRD6,PAAF1,SHANK2,EFHD1,LIMCH1,TRERF1,SYT1,ATMIN,TCF4,TCF7L2,TNS1,SSBP2,DNAJC12,VSNL1,WIPF1,WNT7A,ZNF23,PMEPA1,PDSS2,HRASLS,KAT6A" Coexpression 15588851-Table2 Human Breast_Gatalica05_10genes GeneSigDB 6.50E-03 1.00E+00 3.94E-02 3.91E-01 5 9 "FGF1,GRIA2,IGF1,PTHLH,PTN" Coexpression M2112 Genes whose expression in brain significantly and positively correlated with the duration of all psychiatric disorders studied. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.50E-03 1.00E+00 3.94E-02 3.91E-01 5 9 "NTM,SPIN1,SHC3,CSRNP3,ZBTB38" Coexpression 19061838-TableS13 Mouse Viral_Cairo08_620genes GeneSigDB 6.60E-03 1.00E+00 4.00E-02 3.98E-01 68 328 "ACADM,AGT,SEMA4G,TMEFF1,WASF1,PTBP2,LDB2,LARGE1,SOCS6,CPS1,CYBB,ARMCX2,HEPH,DLG3,GOLT1B,SEMA3D,PCOLCE2,PIPOX,NRN1,ARMCX1,FDFT1,FGF13,EVL,ALDH1L1,GJB1,GLDC,GRIK1,GRIK5,GSTM5,GSTT2,HP,IGFBP1,ITIH2,JAK2,MAOB,MATN2,MEST,MYCN,NNAT,PDGFRA,SERPINE2,PKM,KCTD15,LRP12,PKN2,PTN,PTX3,RAD52,MORC4,SATB1,SH3GL3,ST6GAL1,SLC12A2,SMARCD3,PDZRN3,RBM34,PDZD2,SP4,SYNE2,TACC1,EHBP1,FRYL,TRO,TRPS1,TST,TTC3,TTPA,RPRM" Coexpression M2073 "Genes concordantly down-regulated in DU-145 and MCF-7 cells (lprostate, breast cancer) upon expression of BRCA1." MSigDB C2: CGP Curated Gene Sets (v6.0) 6.67E-03 1.00E+00 4.04E-02 4.01E-01 11 32 "ADD2,AQP4,TJP2,HIPK3,EBI3,JAK1,NUMA1,PKN2,PEX2,TJP1,SEMA3B" Coexpression 12136251-table5 Human Liver_Li02_36genes GeneSigDB 6.67E-03 1.00E+00 4.04E-02 4.01E-01 11 32 "FCGR3A,FYN,HBA1,IFI16,MX1,PTN,SLA,SMARCE1,EPB41L3,RGL1,TAC1" Coexpression 16585221-Table1 Human Stomach_Yamashita06_16genes GeneSigDB 6.70E-03 1.00E+00 4.05E-02 4.03E-01 7 16 "ZBTB10,FGFR1,GLDC,ELOVL5,RDX,CADM1,UCHL1" Coexpression 16862184-Table1 Human Leukemia_Shiraishi07_21genes GeneSigDB 6.70E-03 1.00E+00 4.05E-02 4.03E-01 7 16 "ARHGDIG,CALB1,NFS1,RGS6,FEZ1,TMEM107,PBX1" Coexpression M8791 Genes up-regulated in splenocytes from Foxp3-ires-GFP B6 mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]). MSigDB C7: Immunologic Signatures (v6.0) 6.73E-03 1.00E+00 4.07E-02 4.04E-01 29 118 "DPP10,ATP2B3,CCKBR,CHGB,NDST3,CRMP1,CRYM,RABGAP1L,FAM78B,GPR61,FOXF2,SDCBP2,RUNDC3A,TMEM25,LINGO1,SLC2A6,ATCAY,NEUROD1,NPTX1,PPP2R2C,RYR1,CSRNP3,SLC8A3,SPHKAP,MYO16,ACSBG1,SYT5,FAM155A,DNALI1" Coexpression M13944 Genes up-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [GeneID=2099]) compared to the parental MCF7 cells which do. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.73E-03 1.00E+00 4.07E-02 4.04E-01 35 149 "OSBPL1A,SORCS2,ASPH,DST,SGCE,CACNA1D,THSD7A,SRSF11,ABCG1,CSF3R,CEP170,DUSP9,FRY,FAM13A,PRKAG2,FHL1,FYN,GLDC,FERMT2,HSD17B1,NASP,NPTX1,PALM,PC,FSD1,GRAMD1C,ITSN1,DOCK10,LIMCH1,PEG10,WWC1,TCF7L2,OBSL1,UGT8,GDPD5" Coexpression M2696 Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA [Gene ID=5970] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 6.73E-03 1.00E+00 4.07E-02 4.04E-01 35 149 "KDM5D,FZD9,BIN1,APBA2,GAS7,NOL4,RIPK1,FGF17,CDK5R2,CD38,DGKI,DLGAP1,FHL5,NTM,EGR3,SIRPB1,F3,GAD1,ATP8A2,SRCAP,GJB1,ADAMTS13,TLX1,KCNA1,KCNJ16,BCO1,FXYD7,NOVA1,GPR85,SCG5,SAMSN1,CRB1,AP4E1,FLRT1,ZFP37" Coexpression M9519 Genes down-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 8 versus day 15. MSigDB C7: Immunologic Signatures (v6.0) 6.75E-03 1.00E+00 4.07E-02 4.05E-01 42 186 "SERPINA3,SLITRK1,ALAD,PPFIA4,VAT1L,ASPA,CDH18,CHRNA4,AHCTF1,LINC01278,CORO2B,FOXF2,B4GALNT1,GLDC,GRIA1,DIDO1,GRIK1,ZIC5,KCNA1,OLFM3,L1CAM,INSYN2,MID1,NPPA,PAK3,PCDH9,FXYD1,PRRX1,CCDC144B,PRKCZ,STRC,AP1AR,TNFRSF19,SLC6A1,ZFP1,ANKFN1,ANKRD28,ICAM5,FMN2,CADM2,MARCH8,PAK5" Coexpression 16424041-SuppTable1 Human Brain_Lu06_1128genes GeneSigDB 6.75E-03 1.00E+00 4.08E-02 4.05E-01 185 1008 "RBM10,AP2A2,BIN1,MAP4K3,APOC1,CASK,TMEFF1,ARHGDIA,ASTN1,SLC4A4,EIF4G3,N4BP2L1,KIF1A,ADAM23,ADGRB3,MPDZ,RGS9,SYNJ2,OSGIN2,CACNA1A,KALRN,CAMK2B,CAST,RUNX1T1,KYAT1,CCNT1,USP6,SYNGR3,DCLK1,CDO1,CLGN,TAOK2,PLAA,STOML1,PCYT1B,COL9A1,SLC4A7,RNF14,RGS6,SEC24C,FEZ1,CTH,SLC45A1,MATR3,TOMM20,DAPK3,DCTN1,BLOC1S6,SACS,EXOG,DNM1,CASP8AP2,ACOT8,FARSB,DNM1L,TSPAN5,OPTN,LPAR6,GOLGA7,EIF4G1,RGS17,ENO2,EPS8,ERBB2,PIPOX,EXTL2,ACSL4,EFEMP1,FGF13,ACTL6B,FGR,PRKAG2,UBE2E3,AKAP3,NBEA,CINP,USP16,PDLIM5,RASL10A,FYB1,GABRA1,AHCYL1,GALC,DISC1,GCK,ARFIP1,USP19,GK,ZNF638,GOLGB1,LILRB4,GPD1,STMN2,GRIN2D,PSIP1,MAP4K5,CELF3,MAN1B1,HSPA1L,IGFBP1,IL6ST,IL11RA,KCNC1,KCNJ3,KCNJ4,KIF5A,KIF5C,KTN1,LAMP2,MATN2,MEIS2,MEST,MTTP,MYO7A,NEFM,NEK1,NEUROD2,NHLH1,NOVA2,NPR2,NPTX2,SLC11A2,NUCB2,NUMA1,OGDH,CLDN11,PAH,PCSK2,PDE1B,GPR85,SERPINI1,GPSM2,PLEC,MBOAT7,POU3F4,PKIA,PSMD13,PTH1R,ARID4A,RFX5,RGS3,ROBO1,CLIP1,RXRA,SAFB,SBF1,ATXN2,SEC14L1,TRA2B,HSPA4L,PAAF1,SLC15A2,SNCA,SOX5,SRPK2,TAB2,MPRIP,APOM,STX1A,SUPT5H,SYN1,SYT5,TCEA1,ACSL6,TCF7L2,TEK,DICER1,ITGB3BP,CDK20,TRIO,TRPC3,TRPS1,HSPBP1,HIRA,XRCC4,ZNF23,ZNF32,MKRN3,ZNF189,ZFAND5,SCG2,SEMA3B,ITM2C,HRASLS,AP3B2" Coexpression 15940248-SuppTable3 Human Uterine_Vanharanta05_289genes GeneSigDB 6.77E-03 1.00E+00 4.08E-02 4.05E-01 17 59 "OSBPL1A,BCS1L,AKAP6,TBPL1,NCOR1,ING4,EFS,GAA,EML4,IFI16,NAP1L3,PCMT1,PDE3B,RBBP6,SMARCA4,TCEA1,TMPO" Coexpression M8946 Genes down-regulated in T conv from aged mice: visceral adipose tissue versus lymph node. MSigDB C7: Immunologic Signatures (v6.0) 6.90E-03 1.00E+00 4.16E-02 4.13E-01 26 103 "KLHL13,AQP4,ADGRB1,SLC5A11,IGFN1,SLITRK5,CMTM5,DMD,DTNA,MEGF11,GAP43,ADAM28,GPM6A,GPR12,NXPH2,KCNMA1,MOBP,RSPO2,RTL5,NPTX1,PCSK5,LGR4,LRRC4,SYN2,PCDH15,KCNAB1" Coexpression M8151 Genes up-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 2h. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "C3orf14,NME5,APOC2,ASPH,BCL7A,THSD7A,INA,REPS2,CHN1,CTNND2,DNM1L,MBNL2,DMTN,ADGRV1,GATM,AHDC1,GFAP,GFRA2,TCERG1,PSRC1,CLASRP,KAT7,GYG1,IDH3A,IFI16,KCNB1,STMN1,HNRNPM,PENK,PPP3CA,PSMA6,PTPRD,RGS12,SCNN1D,PKNOX2,GLT8D1,STXBP1,FBXW11,SLC19A3,TGFBR3,MTMR14,ICAM5,ZNF154,PHTF2" Coexpression M7687 Genes up-regulated in ankle joints from SPHK1 [GeneID=8877] knockout: TNF [GeneID=7124] over-expression versus control. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "ACTN2,ANK1,RGS20,PLA2G4C,ARSF,ZSCAN18,ATP2A2,DST,CAMK2A,ARHGAP33,CHRNB2,PICK1,WHRN,CSF1R,SDC3,EDRF1,RUSC2,SNAP91,MAMLD1,TNK2,MFSD10,UFM1,GLS,KCND1,KCND3,KCNQ3,KLC1,PFKFB3,KCTD15,FXYD1,MTRF1L,RGS12,RTN1,SFPQ,SH3GL3,ZNF365,PKNOX2,RAB3GAP1,STX1A,ELP5,PLPPR2,LAT2,NDRG4,PRDM2" Coexpression M7580 Genes down-regulated in CD11b Spleen from BALBc mouse versus CD11b Tumor from BALBc mouse. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "RGS20,CASTOR3,CACNA1I,CD38,LONRF2,AKAP12,CRMP1,NOS1AP,ARRDC4,KCTD3,ENO2,EPB41,RTN3,PRKAG2,CAP2,SYNCRIP,CAMKK2,GNG3,GPR22,HNRNPK,SHISA6,SMAD1,PDE4D,FSD1,DIRAS2,NCR3LG1,USP47,PLEKHB2,SOX8,RYR1,SH3BGR,BTBD3,LIMS2,MCF2L2,TCF4,DMXL2,TCF7L2,TPD52,DCBLD1,ELFN1,LAMP5,SLC30A4,SLC38A1,SNX27" Coexpression M5161 Genes down-regulated in comparison of macrophages versus macrophages exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "PPFIA1,AP4M1,DLGAP1,CHGB,TAOK2,CNR1,DZIP3,PHF14,DCT,CEP170,SACS,G3BP2,DNM2,OPTN,EFNA3,MBNL2,ELAVL3,CACNG3,CSPG5,DKK3,INPP5K,GLS,GRIK1,PSIP1,INPP1,SMAD1,AFDN,PCDH8,PDE1A,PDE1C,PPP3CB,MAPK7,PYGM,KCTD17,SLC12A4,SOX15,KIF1B,IQSEC2,ITPRID2,SST,CNTN2,RIMBP2,SLC13A3,SLC30A4" Coexpression M8006 Genes up-regulated in wildtype bone marrow-derived macrophages: control versus treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "ASIC1,ALDH7A1,NOG,FOXN3,CHN2,LY86,HDAC9,ARHGAP32,TOX,DAPK1,SV2A,DPYSL2,ABI2,C3orf18,CEP85L,HVCN1,ZNF234,SEPT9,GCNT2,SPIN1,GLUL,GNAS,GUCY1B1,MSL1,ZNF667-AS1,NFE2L2,PCDH9,RALGDS,ZDHHC14,RTKN,RXRA,ATXN1,SEC14L1,SGK1,BTBD3,LIMS2,USP33,SYPL1,DNMBP,TCF4,TRIO,ZNF711,INTS3,SENP7" Coexpression M5544 Genes up-regulated in comparison of B cells versus central memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "AMPD3,NUMB,BAIAP3,CACNA1A,COPB2,PPP1R16B,CYBB,RASSF2,SCRN1,ARMCX2,ZNF804A,E2F5,SIDT2,CHST15,FGR,SEC23B,SYT17,HPS5,BACH2,IRF8,LMO2,MEF2C,MKLN1,CD200,PCDH9,FA2H,SIDT1,ZSCAN32,ZDHHC4,TMEM156,DGLUCY,MAPK12,SEC14L1,CASC3,GALNT10,SHMT2,SYPL1,FBXW11,TCF4,USP22,TST,LAT2,FTSJ1,LAMP5" Coexpression M8755 Genes down-regulated in T cells stimulated by IL2 [GeneID=3558] for 17h: STAT5 double knock-in versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 6.94E-03 1.00E+00 4.17E-02 4.14E-01 44 197 "ACTN1,PDXK,NCOA1,ATP1B3,BACH1,MTMR3,AP1M1,CCPG1,MAP4K4,SIPA1L1,FGFR1OP2,FRY,EGR3,F5,FAM198B,CHST15,SEC23B,HVCN1,FYB1,GALC,PSRC1,GRB10,IRAK3,TOX2,ITGAM,LDLRAD3,ING3,ARHGEF10L,STK32B,CLIP1,ATXN1,CPEB4,KIF13A,SPART,AGTPBP1,TCF7L2,TPCN2,WASHC4,TLR4,ANO5,PLPPR2,EVI5,NLRP3,ZDHHC20" Coexpression M2776 Cluster 1: genes up-regulated in lung tissue samples from mice with oncogenic form of KRAS [GeneID=3845] and inactivated PTEN [GeneID=5728]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.97E-03 1.00E+00 4.18E-02 4.16E-01 41 181 "AXIN2,INTS2,ATP6V0A1,BCHE,LDHD,CALB1,CP,PLCH2,SDC3,APPL1,DTNB,ELAVL3,ERCC2,CDHR1,F3,FER,TMEM107,KBTBD12,TVP23A,GABRA1,CHL1,ZMYND11,GRIN1,KIF2A,LAMP2,MAP6,NEFM,NUCB2,OPRL1,ZNF827,POLG,RAB39A,MAPK8,RET,ZC3H14,SUPT20H,INAVA,TCF7L2,WNK1,CA10,ADAMTS10" Coexpression M9003 Genes up-regulated in CD4 [GeneID=920] T cells over-expressing FOXP3 [GeneID=50943] and Pparg2 isoform of PPARG [GeneID=5468]: untreated versus pioglitazone [PubChem=4829]. MSigDB C7: Immunologic Signatures (v6.0) 7.05E-03 1.00E+00 4.23E-02 4.20E-01 33 139 "ADCY6,PLA2G6,C1QTNF3,SPARCL1,BBOX1,CACNB2,KYAT1,CDH10,RAB33A,USP3,STX2,NEURL4,IGSF21,MBP,MDM4,MN1,ZDHHC22,PFKFB2,NLGN3,SDK2,GRAMD1C,PTH1R,SATB1,PEAR1,FERMT1,DZIP1,GLT8D1,COLGALT2,TCF7,FLRT1,DNALI1,PRDM8,NETO2" Coexpression M10023 Genes down-regulated in NK cells versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.05E-03 1.00E+00 4.23E-02 4.20E-01 33 139 "CC2D2A,PLA2G6,FAM131A,CACHD1,MARCH3,CNOT8,SEMA3D,CELSR3,CALCRL,EN2,DENND4A,SYNCRIP,FLYWCH1,ST6GALNAC3,PLD5,SCIN,KCNJ11,AFDN,WDR49,ADAM22,MXI1,FXYD7,OPRL1,PCSK5,PDE3B,PDE4D,UHRF1BP1,CNTNAP3,LHFPL4,ADGRL3,SMG6,SLC19A3,FTSJ1" Coexpression 18667080-TableS3 Human StemCell_Kocer08_44genes GeneSigDB 7.06E-03 1.00E+00 4.23E-02 4.20E-01 10 28 "PRC1,SLC4A7,DCT,DPYSL2,EDNRB,DKK3,TOX3,GPM6B,WIF1,PCDH8" Coexpression 12649203-Table1b Human Lung_Jimenez03_31genes GeneSigDB 7.06E-03 1.00E+00 4.23E-02 4.20E-01 10 28 "ALCAM,CDH8,FOXN3,CNTN1,PHC2,KLF12,MMP17,NRCAM,PCDHA6,ITGB3BP" Coexpression M16941 Genes up-regulated in fibroblasts expressing different mutant forms of ERCC3 [GeneID=2071]: XP/CS (xeroderma pigmentosum (XP) and Cockraine's syndrome (CS)) vs TTD (trichothiodystrophy). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.06E-03 1.00E+00 4.23E-02 4.20E-01 10 28 "ADORA1,LHX2,RIMS2,RASSF2,E2F5,GNG4,MEST,PTPRN,PTX3,EPB41L3" Coexpression 19118056-SuppTable5 Human Lung_Roepman09_72genes GeneSigDB 7.12E-03 1.00E+00 4.26E-02 4.23E-01 15 50 "C1QTNF3,RASL11B,CD38,GPSM1,CNIH3,ACOT8,GSTT2,HMGCL,USP51,IL11RA,PSMA6,SLC4A3,OBSL1,TPD52,TRO" Coexpression 20368555-TS-3 Human Breast_Barry10_52genes GeneSigDB 7.12E-03 1.00E+00 4.26E-02 4.23E-01 15 50 "NRP2,FBXO7,ZEB2,DLG3,ST3GAL6,GPM6B,GSN,KCNK1,MEST,MITF,MMP17,PMP22,ZCCHC24,STXBP1,PCDHGC5" Coexpression M1138 "Genes up-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing a constantly active form of NRAS [GeneID=4893] off a plasmid vector compared to those grown in the presence of IL6 [GeneID=3569]." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.17E-03 1.00E+00 4.29E-02 4.26E-01 13 41 "OSBPL1A,CD86,LY86,HOMER3,CX3CR1,CYBB,SV2B,GATM,MALT1,GPM6B,MSR1,NCF2,TUBB2A" Coexpression M2630 Genes down-regulated in mouse fibroblasts over-expressing E2F1 [Gene ID=1869] gene. MSigDB C6: Oncogenic Signatures (v6.0) 7.18E-03 1.00E+00 4.29E-02 4.26E-01 43 192 "SERPINA3,AMPD3,APBB2,TRIM41,RUNX1T1,ENTPD6,CSF1,LRIG1,VCAN,PDE4DIP,DCAF8,EBF1,EPS8,APC2,F3,FER,TRAF3IP2,GFRA1,USP19,GHR,SYNPO,IL6ST,MX1,SLC11A2,NUMA1,PAK3,PDGFRA,PKD1,PPP3CA,ANKHD1,RALGDS,RTKN,HES6,RASA3,SGK1,SLC6A8,FCHO1,ZFR2,TCF4,ZMYND8,UBE2H,NDRG4,NHSL1" Coexpression M8884 Genes down-regulated in hematopoietic stem cells versus granulocyte-monocyte progenitors. MSigDB C7: Immunologic Signatures (v6.0) 7.19E-03 1.00E+00 4.29E-02 4.26E-01 40 176 "ACLY,AXIN2,PPP4R4,DPY19L3,ATP6V0A1,VSTM2A,MAGI1,AKAP7,AKAP12,CLIP3,SPOCK2,RASGRP1,EBI3,SORBS1,GALC,MALT1,ADAP1,NR3C1,IRAK3,HMGCR,RBPJ,ITGAV,KIT,NUCB1,GNG2,GRAMD1C,PTPN13,CCDC112,ATXN1,SEC14L1,TRIM46,UHRF1BP1L,SYNE2,IQCE,DNAJC12,MAP3K12,NAV2,PCBP4,MARCH8,RTN4" Coexpression M6728 Genes down-regulated in spleen dendritic cells from Flt3L Melanom injected mice: 33D1+ versus DEC205+ subpopulations. MSigDB C7: Immunologic Signatures (v6.0) 7.19E-03 1.00E+00 4.29E-02 4.26E-01 40 176 "NDRG3,ATP2B1,LARGE1,MAGED1,NCOR2,MICAL2,PDE4DIP,PLEKHM1,SIDT2,SLC43A2,PCYOX1,GALC,TUBGCP4,GPR162,SESN1,ADAP1,ARHGAP19,IL6ST,TUBB2B,KCNJ10,NUMA1,PIK3R1,PPP3CB,OXR1,RNASEL,TMEM206,WLS,ATXN1,RASA3,ELMO2,CDK19,ITPRID2,ZC4H2,MPRIP,SULF2,TCF7L2,ARHGAP9,ATP13A2,LAT2,AAAS" Coexpression M7657 Gene predicting resistance of the NCI-60 cell lines to gamma radiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.22E-03 1.00E+00 4.30E-02 4.27E-01 8 20 "CHGA,COL11A2,CRMP1,EDNRA,TUBA1B,KLRC3,SLC22A4,WNK2" Coexpression M8941 Down-regulated genes distinguishing between two groups of non-BRCA1/BRCA2 [GeneID=672;675] breast tumors (BRACx): group A vs group B. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.22E-03 1.00E+00 4.30E-02 4.27E-01 8 20 "ARHGEF7,SRSF11,SYNCRIP,HPS5,AFDN,NAP1L1,OCIAD1,EVI5" Coexpression M1189 The lung adenocarcinoma TSP (tumor sequencing project) genes mutations in which show positive correlation with the higher overall mutation rate. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.22E-03 1.00E+00 4.30E-02 4.27E-01 8 20 "DDR1,LRP1B,NTRK2,PDGFRA,PTPRD,PTPRG,ROBO2,VAV1" Coexpression 17088983-Table2b Human Viral_Tsunedomi06_23genes GeneSigDB 7.22E-03 1.00E+00 4.30E-02 4.27E-01 8 20 "N4BP2L1,SEMA6C,RND1,LAMP2,PIK3R1,PTPRD,SGK1,ZFAND5" Coexpression M1437 Down-regulated genes in myeloid progenitors immortalized by HOXA9 [GeneID=3205] vs those immortalized by HOXA9 and MEIS1 [GeneID=4211]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.28E-03 1.00E+00 4.33E-02 4.30E-01 9 24 "ADGRG1,LY86,EBF1,EDNRA,CALCRL,MEIS1,NRGN,SATB1,ZBTB16" Coexpression 20211691-Table1 Mouse NeuronalCells_Provenzano10_29cells GeneSigDB 7.28E-03 1.00E+00 4.33E-02 4.30E-01 9 24 "ADCY8,SEC24C,DBN1,KCNK2,SYTL4,RSPO2,CADM1,PCDH20,PAK5" Coexpression 19204596-Table3 Human Muscle_Stepto09_161genes GeneSigDB 7.30E-03 1.00E+00 4.34E-02 4.31E-01 36 155 "ARSF,CAST,LDB2,AIFM1,CLTB,COL11A2,SLC4A7,CSF2RA,LPAR6,REEP2,ARMCX1,NBEA,GBX2,GPR34,LIFR,MAG,MSR1,MSRA,NEK1,NOVA1,SCHIP1,PMS2,PTPRE,PTPRO,HUNK,KCNIP3,SYP,ACSL6,TCF4,TEK,TRPS1,BEST1,ZSCAN26,CSDE1,SSPN,JPH3" Coexpression M417 Genes down-regulated in dendritic cells: immature versus mature stimulatory. MSigDB C7: Immunologic Signatures (v6.0) 7.35E-03 1.00E+00 4.37E-02 4.34E-01 31 129 "CSMD3,FMNL2,SLC12A5,LRRC7,KCNT1,RGS9,ST18,EGFR,TMEM35A,FOLH1,KHDRBS3,KLHL23,MSR1,GLIPR1L2,FTO,RAB39A,PSD,LGI2,RTKN,MYO16,SPATA7,PBLD,COLGALT2,GPR161,TPD52,LRTM2,TMEFF2,VLDLR,KCNK12,KCNAB1,EPM2A" Coexpression M8909 Genes down-regulated in dendritic cells: unstimulated wildtype versus KDM4D [GeneID=55693] knockdown (shRNA) stimulated by LPS. MSigDB C7: Immunologic Signatures (v6.0) 7.42E-03 1.00E+00 4.41E-02 4.38E-01 39 171 "NDRG2,SLC12A5,PPP4R4,ASPH,ATP6V0A1,DST,CANX,AKAP7,C2CD2,FBXL5,CD99L2,ARRDC4,EML1,STX2,KATNAL1,ARMCX1,ATP8A1,NCKAP1,GGTA1P,GGT7,SPIN1,PADI2,ATCAY,ICA1,ITGAV,KIT,PDE1B,PLCL1,PSAT1,PRKCZ,LRRC49,ZFP1,MAPKBP1,SLC37A2,ARHGEF12,TPD52,NAV2,MARCH8,RTN4" Coexpression 19893615-Table3 Human Thyroid_Fontaine09_220genes GeneSigDB 7.42E-03 1.00E+00 4.41E-02 4.38E-01 39 171 "ALCAM,ANK2,VAT1L,ASGR1,ATP6V1G2,CALM1,CBFA2T2,CD38,CLGN,NUMBL,CERCAM,EMX2,ABCA8,GNAS,GRB10,IDH3B,KCNQ2,ZNF862,NBL1,PAX6,ABCB1,CEP97,KLHDC8A,RPS6KA2,SLC6A8,TTC17,SNCB,ZNF415,SST,KIAA0930,TIE1,FAM124A,CABIN1,TPM2,ZBTB16,DNALI1,LRP8,ADAMTS9,AAAS" Coexpression M2873 Genes up-regulated in HEL cells (erythroleukemia) after knockdown of JAK2 [Gene ID=3717] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 7.43E-03 1.00E+00 4.41E-02 4.38E-01 42 187 "ADCYAP1R1,ASGR1,ADGRB1,CACNB4,INA,LARGE1,DLGAP1,GPR37L1,JAM2,NDST3,AKAP6,LRIG1,ATRNL1,PHF14,DMD,PIPOX,DOT1L,TUBA8,GRM5,HRH3,TLX1,HPR,KITLG,NELL2,PDZRN4,LAMA1,SIDT1,PTN,PTPRO,ZSCAN2,ZFHX4,NEK11,ZNF821,FRMPD1,CNKSR2,SLC8A1,SNCB,ZEB1,PCDHGA9,RALYL,BHLHB9,NAV2" Coexpression M2976 Genes up-regulated in natural T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 7.50E-03 1.00E+00 4.45E-02 4.42E-01 35 150 "GRAMD1B,MAP4K3,APC,CAST,FOXN3,CRMP1,TOX,MAML1,SRGAP3,RABGAP1L,USP3,RASGRP1,TACC2,ZBED3,ADAMTS6,IRAK3,ICA1,EID2B,GIT1,MX1,NUCB1,PGAM2,SPATA6,PPP3CC,PTPN13,CNTNAP3,ATXN1,PEAR1,ARHGAP26,SAMSN1,MAPK8IP3,TBCEL,ATMIN,ARHGEF12,ZBTB38" Coexpression 17597811-SuppTable9 Human Leukemia_Mullighan07_91genes GeneSigDB 7.61E-03 1.00E+00 4.49E-02 4.46E-01 20 74 "MRTFA,DGKD,CALM1,CAPN3,CD81,TPP1,COL4A5,DZIP3,PLXNC1,CAMKK2,GPM6B,KIF3A,ITGA7,ITGAV,PDE3A,SCHIP1,DOCK9,CHST5,KCNE5,JMJD1C" Coexpression 19192944-table2 Human Ovarian_Crijns09_86Genes_OverallSurvival GeneSigDB 7.61E-03 1.00E+00 4.49E-02 4.46E-01 20 74 "C1QTNF3,PTCH2,CACNA1B,CNTFR,ZNF521,CRYBB1,FEZ1,FGFR1OP2,LRRC17,TUBB4A,BRSK1,SIGLEC8,KLF12,JAK2,PTPRN2,KLHL7,SYT11,WDR7,TRO,SPATA13" Coexpression M12746 Genes up-regulated in NCI-H1299 cells (large cell neuroendocrine carcinoma) stably expressing SEMA3B [GeneID=7869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.61E-03 1.00E+00 4.49E-02 4.46E-01 61 291 "DPF1,FMNL2,ADRB2,SRPX,PITPNM2,LRCH2,MARK4,KSR1,CLDN10,UBE2L6,C4orf33,RAB26,SLC35F1,CREB5,CLIP3,ST18,SIRPA,DLG3,MAMLD1,HSD17B14,EN2,ERCC2,SPEG,DLC1,FGF1,CELF1,GALC,SALL3,TOX2,NXPH2,IL12A,KCND1,KCNMA1,KIF5C,KPNA5,MID1,RTL5,NOVA1,OPHN1,PAX6,SERPINI1,ST8SIA5,POU3F4,SH3TC2,SUSD4,SETD5,PRR5L,CNTNAP3,KIF16B,SMTN,TTC17,STAU1,SUPT5H,SYT1,SYT5,PCDHB6,BEX4,UBE3A,LAT2,SLC38A1,SEMA3B" Coexpression M4401 Genes down-regulated in comparison of regulatory T cell (Treg) versus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "METAP1D,GOLGA7B,APP,ATP1A1,ATP6V1G2,FMNL3,CNRIP1,CTNND1,RIPOR2,DNAJC6,EIF4G1,RAB9B,ARMCX1,PRKAG2,GRB10,COQ10A,TMEM25,USP51,THYN1,MXI1,MYH3,NDP,NFIA,OCRL,PDE4D,POU6F1,LRRN3,SLC22A23,ZIK1,ZNF493,ZC3H14,RPS20,ABCA11P,SH3BGR,STXBP1,KIAA1107,TCF7L2,SSBP2,ZNF24,MICU3,PMEPA1,ADAMTS10,KLHDC1,ZNF30" Coexpression M6271 Genes up-regulated in cortical thymic epithelial cells (cTEC) versus thymic dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "ADCY8,AP2A1,PKP4,CADPS,SYNJ1,WASF1,CLOCK,TENM4,LRIG1,TMEM130,GSDME,GOLT1B,EXTL2,TESK2,POLK,KHDRBS3,GALC,ALDH1L1,PARD3B,ITGA7,SCAMP5,MSR1,NELL2,KCNK10,NALCN,ZNF655,PLTP,SPATA6,DIRAS2,ZSCAN2,TTLL7,PRR5L,RTKN,SSPO,RGL1,COBL,SLC37A2,TACC1,TIAM1,CDK20,TRPS1,CADM1,MICAL1,WIPF1" Coexpression M8674 Genes up-regulated in monocytes (24h): untreated versus muramyl dipeptide [PubChem=11620162] andM. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "GALNT16,ADCY2,ANK1,AQP6,KIAA1614,NUMB,ALDH7A1,SEC11C,RGS11,CA4,CD86,NEURL1,CDH2,GALNT9,INTS1,SIRPA,DGCR5,EMX2,RTN3,PTK2B,DPYSL4,GAB1,FREM1,FERMT2,RNF165,HES5,KCNN3,KIT,LSAMP,MTTP,HS6ST3,PCDH18,PNMA3,EPB41L4B,PILRA,DEF8,PTAFR,RGS3,SNX22,FOXRED2,IQCE,LILRA4,SLC4A10,JPH3" Coexpression M5250 Genes up-regulated in comparison of macrophages exposed to L. major versus macrophages exposed to 5 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "SYN3,ACTN1,MTMR9,NAE1,SGCE,DLGAP1,CHGB,FBXO7,GAPVD1,BRINP1,DYNC1I1,DPP6,SPEG,FCGR3A,ATP5PD,CAP2,DKK3,ZNF44,GART,RNFT2,SYNPO,HSP90AA1,KCNK1,KTN1,SLC11A2,NRDC,PCDH8,PDE1A,PFKP,PHKG1,PKM,PPP3CB,RYR1,FAM214B,SLC12A4,ZSWIM8,FCHO1,NCDN,WSCD1,RIMBP2,FAM155A,UBE3A,TFIP11,NAV3" Coexpression M4309 Genes up-regulated in comparison of contols neutrophils versus those infected with a bacterium (F. nucleatum). MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "ADAR,AGT,ALCAM,CNTNAP1,DNAH17,ATP1A1,FGF17,CFAP410,MAP7,DGKI,MAGI1,COL9A1,HS3ST2,FGR,CAMKK2,KHDRBS3,LUZP2,GPR22,HMGCL,INSM1,MBD1,MYO7A,NCAM1,PHKG1,CCSER2,FAM120C,CCDC40,SETD5,PRR5L,FRMPD1,SLC6A8,CCDC88A,MYH15,PALLD,TSNAXIP1,SST,MLST8,KLHL4,SZT2,SEZ6L,TRIO,CADM1,ETNPPL,EPM2A" Coexpression M8726 Genes down-regulated in bone marrow-derived macrophages treated with LPS for 4h: heterozygous versus homozygous knockout of MLL4 [GeneID=9757]. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "SLC24A4,ALAD,FGD2,APOC1,ATP6V0A1,C5,CAPN3,RCBTB2,CHN2,CNOT8,TPP1,LY86,ARHGEF6,CRHBP,SIPA1L1,IST1,ABCC5,SNX29,FAM13A,MBNL2,LPAR6,SORBS3,TLR7,ZBED3,TPK1,GGTA1P,SPIN1,KCNMB4,STMN1,MDM4,MEF2C,FXYD6,TREM2,PIK3R1,GDPD1,ASRGL1,SPATA7,RAP1GAP2,ADHFE1,PLCB1,FAM208A,ACSL6,CCDC14,TTC7A" Coexpression M3596 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "ADCY6,BRAP,AP1B1,MAP4K3,APP,CAMK2B,USP2,CLTB,NGEF,ABCG1,SOCS5,NR1D2,ABCC5,EEF1A2,ERCC2,TLR7,TUBB4A,PRMT5,FOLR2,ST6GALNAC3,DKK3,GABBR1,PPARGC1A,GRIK1,COQ10A,KIT,NAP1L2,NTRK3,CNTN3,PDE4B,PDE1B,PKD1,PLCD1,MTMR10,RAB3A,BSDC1,RPS6KA2,GALNT10,SH3GL2,SOX2,TROVE2,ST5,MAPK8IP3,KCNAB1" Coexpression M4218 Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h versus the untreated cells at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "ABHD6,OLMALINC,ARRB1,EIF4G3,HAP1,NOG,CIART,IPCEF1,PHACTR3,ECE2,DGKB,FAM107B,AASDH,ATP2C1,MALT1,GK,CRCP,GNAL,GPD2,TDRKH,MAP4K5,TOX2,TLX1,IL6R,IL12A,MBP,LRP1B,SAMD5,MXI1,NINJ2,PDE4D,PFKFB3,SYTL2,CCDC82,SGK1,STAC2,CAMSAP2,GPRIN3,R3HDM1,NPL,TPM4,CLIP2,TTC7A,JPH3" Coexpression M9578 Genes up-regulated in T reg: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 7.62E-03 1.00E+00 4.49E-02 4.46E-01 44 198 "CLK4,C3orf14,OSBPL8,BMPR1B,TMEM257,CNOT8,RAB33A,LY86,ECE2,TBC1D5,KIAA0586,SIRPA,KMT5B,ADGRV1,GMPR2,AMZ2,VTI1B,NELFCD,GABBR1,DENND2A,GAP43,DIDO1,RNFT2,ADAMTS6,AGBL5,JAK1,MBP,AFDN,NF1,OLA1,PPP3CA,TMEM260,PEX2,RAB5B,OXR1,MSANTD2,SH3GL3,ZKSCAN3,DOP1A,SST,AP4E1,NACC2,TNFRSF1B,ZBTB14" Coexpression M6504 Genes down-regulated in monocyte-derived dendritic cells: LGALS1 [GeneID=3956] versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 7.65E-03 1.00E+00 4.50E-02 4.47E-01 38 166 "HECW2,KCNAB2,CPNE5,SLC7A14,PDXK,B3GALT2,BID,ST3GAL5,CARS,MYOM2,CLGN,CHN1,LY86,ATRNL1,GSDME,AASDH,RTN3,FDFT1,SEMA4D,SGIP1,FYN,NFU1,CSDC2,GGTA1P,KIRREL3,DISP2,IPO5,KLK6,LAMA1,PTPRE,LHFPL4,UHRF1BP1L,SPP1,LARP4,ATP11A,TEX15,TFIP11,NELFE" Coexpression M6923 Genes down-regulated in B lymphocytes: control versus PL2-3 (Chromatin IC). MSigDB C7: Immunologic Signatures (v6.0) 7.65E-03 1.00E+00 4.50E-02 4.47E-01 38 166 "ALCAM,USP37,APP,BLM,LDHD,JAZF1,IL33,BTRC,AIFM1,CDO1,FBXO7,CNN3,FEZ2,VCAN,TCAF1,RABGAP1L,MBNL2,COPS4,ACSL4,SEC23B,SYT17,GGTA1P,STARD3,DBNL,PDE4D,PRKAB2,PSMD13,LRRK2,ST3GAL3,TET1,TCEA1,TCF4,SIRT1,DDHD1,BEST1,KLC2,CAB39L,NLRP3" Coexpression 18849563-SuppTable2 Human Lung_not_cancer_Bhattacharya09_65genes GeneSigDB 7.67E-03 1.00E+00 4.51E-02 4.48E-01 16 55 "RUNX1T1,SLIT2,QKI,ZNF44,KIT,KITLG,PTCH1,SEMA6D,TNFRSF19,SLC12A2,RBM26,ZNF302,HIF3A,PLEKHH2,ZNF248,ZNF30" Coexpression M6977 Genes up-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.67E-03 1.00E+00 4.51E-02 4.48E-01 16 55 "APBA2,CASK,ASPA,CAMK2G,CD38,CBARP,RGS6,ST8SIA3,FAM13A,EGR3,PTK2B,C1orf61,KITLG,PDYN,APOM,AJAP1" Coexpression M8519 Genes down-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.68E-03 1.00E+00 4.52E-02 4.49E-01 41 182 "LTBP4,AMPD2,CACNA1G,NRXN2,SNCAIP,TRAPPC9,EEF1D,EGFR,SORBS3,ERBB2,DLC1,SCARA3,DENND2A,LAMA2,NNAT,PMP22,MAGEL2,PTH1R,PTN,PTPN13,C1orf54,FAT4,RGS10,ZFHX4,CCDC25,WLS,CSRNP3,ASAP3,SLC1A3,ARHGEF40,RGL1,KAZN,PSD3,OBSL1,HIF3A,HEY1,TRPS1,ZIC1,SEMA3B,NAV3,ITM2C" Coexpression M2779 "Genes up-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi." MSigDB C6: Oncogenic Signatures (v6.0) 7.70E-03 1.00E+00 4.52E-02 4.49E-01 34 145 "ADRB2,APBB2,MARCH3,ASPH,NRP2,C2CD2,HAPLN1,CSF1,ZEB2,RUSC2,C2CD2L,NTM,EDN1,PLEKHO1,F3,SCML2,HAS2,KCNN3,LSAMP,PSAT1,PTHLH,NKAIN1,ABLIM3,SLC6A9,SLC22A4,KIF21B,STX1A,FAM189A1,TEK,ATP13A2,TRIO,VLDLR,PMEPA1,NAV2" Coexpression M2137 "Genes identified as synthetic lethal with imatinib [PubChem=5291] in RNAi screen in K562 cells (CML, chronic myelogenous leukemia)." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.70E-03 1.00E+00 4.52E-02 4.49E-01 34 145 "ANK3,API5,TMEFF1,AZGP1,LDLRAD4,CALM1,CAMK2B,CARS,CACNA2D2,CLTA,CLTC,CNR1,NRG2,PDE4DIP,MAML1,PLEKHM1,SV2B,EGR3,SORBS1,PDLIM5,CRCP,DBF4,IFI16,ADAM22,SNX10,GLT8D1,SPTB,TROVE2,SYT11,HIF3A,TJP1,TPM1,UBE3A,KAT6A" Coexpression M6748 Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.70E-03 1.00E+00 4.52E-02 4.49E-01 34 145 "ADD3,CDC42BPA,APP,ATP6V0A1,CAST,B4GALT6,FADS2,NECTIN3,RHOBTB1,DTNB,TSPAN5,EGFR,EPS8,FGFR1,FOLR2,TPK1,IQGAP2,LYVE1,GLUL,HTR2A,ITPKA,MEF2C,NME4,CDK14,PTK2,PID1,SLC12A2,SLC14A1,SCN3B,PEG10,SYPL1,TRIM2,PSD3,TST" Coexpression M6677 Genes down-regulated in bone marrow-derived macrophages at 180 min of stimulation with IL10 [GeneID=3486] and LPS: wildtype versus IL10 [GeneID=3486] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.72E-03 1.00E+00 4.53E-02 4.50E-01 28 114 "ADORA3,PPFIA2,LRRC4C,ADGRB3,P2RX6,MYOM2,PLCH2,NRSN1,AASS,CACNG2,PRELID3A,GALNT15,B4GALNT4,TMEM179,KCNQ3,KIFC3,PACRG,PTPN13,SUSD4,ENOX1,SCN2A,FERMT1,SPHKAP,SOX10,LHFPL4,TCF7,ICAM5,MEIS3" Coexpression M1833 "Spermatozoa genes, based on mouse models with male reproductive defects." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.72E-03 1.00E+00 4.53E-02 4.50E-01 28 114 "PLA2G4C,BBS2,NIPA1,SPAG9,CD81,CLGN,FHL5,CREM,SH2B1,CPLX1,PLCD4,AGFG1,INPP5B,PACRG,PLTP,SEPT4,POLG,HSPA4L,FNDC3A,SLC12A2,PLCB1,AGTPBP1,SIRT1,TSN,CADM1,VIPR2,LRP8,GOPC" Coexpression 19305503-Table2 Rat Brain_Greco09_84genes GeneSigDB 7.76E-03 1.00E+00 4.55E-02 4.52E-01 21 79 "ABAT,ATP1A2,BMP7,CALB2,CDO1,FHL1,GPR37,NEFM,NFE2L2,PC,PDE4B,PRPH,SLC6A1,SLC9A5,SST,SSTR1,SSTR2,TAC1,TACR1,RASD2,SLC17A6" Coexpression M8144 "Genes up-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h." MSigDB C2: CGP Curated Gene Sets (v6.0) 7.76E-03 1.00E+00 4.55E-02 4.52E-01 175 952 "RALGAPA1,FMNL2,BRAP,PLEKHH1,ESYT2,HACE1,OGT,CDC42BPA,PKP4,GAS7,USP37,ARRB1,NUMB,STX16,DCAF5,BID,KSR1,SYNJ1,ARHGEF7,SCAPER,CAST,CARS,MAP7,CBS,SCARB1,CCPG1,UBE2L6,NPIPA1,RCBTB2,FOXN3,ARMC8,LETMD1,ENTPD4,RBM39,PNPLA8,CTH,CYBB,HDAC9,EARS2,DBN1,ZEB2,DDX46,USP3,NR1D2,CPEB2,SLC12A6,GNE,ARRDC4,ABCC5,KLHL5,FSD1L,SH3GLB1,MBNL2,LINC-PINT,LINC00599,EIF5,IRAK4,PLEKHA1,ING4,EIF1,RABEPK,ANKMY1,CD320,RPS6KC1,SH3YL1,PTK2B,FCGR1B,GORAB,NOP56,TPK1,OGA,FYN,ZNF274,ERAP1,MTHFD2,INPP5K,USP19,TXNL4A,GPT2,GOLGB1,ADGRA3,GRB10,SPACA9,NR3C1,PSIP1,MGC16275,MIER3,HMGCL,AGFG1,LINC00667,INPP1,ITGAV,ITPKB,JAK1,LSS,MDM4,MIA2,MYO5A,ZNF862,NASP,NEK1,ALDH1L2,NRDC,OGG1,PDE4D,SSH1,PKD1,RETREG1,SMOX,PRIMPOL,PSAT1,SLC36A4,POLG,TATDN3,PRKACB,APTX,PTPRE,TUG1,PPP2R3C,CEP97,RAD51D,ARID4A,BSDC1,RET,RFX3,SLC25A36,ADAL,TCP11L1,CLIP1,SARS,ATXN1,SEC14L1,SH3BP2,SHMT2,CCDC92,RUFY2,CPEB4,GKAP1,ZCCHC24,KIF21B,UHRF1BP1L,KIF1B,CDK19,ZNF621,COLGALT2,EPB41L3,ZSCAN29,TTBK2,PRRC2C,ARHGEF9,SEMA4A,MLST8,TAF9,TBL1X,TCF4,TCF12,AKNA,ARHGAP9,AKTIP,CBX5,TPM4,SSBP2,UBE2H,DNAJC12,FLRT2,VLDLR,PCBP1-AS1,FTSJ1,WNK1,EMSY,TUBA1A,VPS35L,ACTR3B,NHSL1,RNF146" Coexpression M461 Genes down-regulated in vascular smooth muscle cells: control versus treated with IL17A [GeneID=3605]. MSigDB C7: Immunologic Signatures (v6.0) 7.81E-03 1.00E+00 4.57E-02 4.54E-01 27 109 "ADRA1B,KLHL13,CCKBR,RCBTB2,CTH,TBC1D5,CCDC3,TMEM35A,GGTA1P,BRD8,GLUL,LILRB4,KLHL23,KCTD6,MSR1,GNG2,FTO,SDK2,MARCH1,LGI2,CMTR2,SOX1,BEX1,PCDHB10,MTMR14,XRCC4,TMEM198" Coexpression 20032505-TableS3 Human Leukemia_Stam09_97genes GeneSigDB 7.86E-03 1.00E+00 4.60E-02 4.57E-01 22 84 "APP,PROM1,BTK,MAP7,LARGE1,FEZ1,DBN1,SMG7,FGFR1,LILRA1,LIG4,SMAD1,MBNL1,PRRX1,RBBP6,SMARCA4,SPTAN1,CEP68,RGL1,MLC1,PARD3,ZNF45" Coexpression M9015 Genes up-regulated in CD4 [GeneID=920] cells after immunization: wildtype versus CTLA4 [GeneID=1493] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.88E-03 1.00E+00 4.61E-02 4.58E-01 37 161 "ACTN1,OSBPL8,ABCD2,PARG,APAF1,DGKD,MIER1,ASTN1,ATM,ABCG2,ERC2,SLC12A6,AHCYL1,RAPGEF6,ARPP21,SPIN1,ATE1,HPS5,NCKAP1L,CLEC18A,PBX1,CYTL1,PKIA,VPS13C,FAM120C,CEP97,REV3L,SCP2,RASA3,CNKSR2,EPC1,LMBRD1,KIF1B,CDK20,SGK3,TOM1L2,KAT6A" Coexpression 20077526-TableS3 Human StemCell_Hao09_612genes GeneSigDB 7.89E-03 1.00E+00 4.61E-02 4.58E-01 87 438 "CLK4,AXIN2,USP31,KIAA1211,TXNDC16,ZFYVE28,ARNTL,ASPH,DST,RAB29,CALB2,CANX,DCLK1,RCBTB2,MAP4K4,COL9A3,NECTIN3,CPS1,VCAN,HDAC9,GSDME,RABGAP1L,KBTBD11,EDNRA,FAM13A,EGFR,MBNL2,ERCC2,CDKL3,IP6K2,PCYOX1,TACC2,PDLIM5,SRCAP,GLS,RAB40B,GNAS,GPM6A,GRB10,PRDM5,GSN,GSTT2,CPT1C,ZIC5,IBA57,METTL21A,KCNK1,L1CAM,MAT2A,MEIS2,MID1,POC1B,MITF,MTR,NFIA,SERPINI1,TMEM38A,KCTD15,PSAT1,OXR1,ARHGEF10L,TCP11L1,RPS6KA2,WLS,SEC14L1,CHD9,SYBU,SLC1A3,CPEB4,SMARCE1,PEG10,CEP68,SULF2,KLHL7,SATB2,DOCK9,SLC44A1,TIAM1,TPM2,TOM1L2,VSNL1,XRCC4,NDRG4,PMEPA1,FZD3,MSRB3,NETO2" Coexpression M8725 Genes down-regulated in bone marrow-derived macrophages with heterozygous MLL4 [GeneID=9757] knockout: 2h LPS versus 4h LPS. MSigDB C7: Immunologic Signatures (v6.0) 7.89E-03 1.00E+00 4.61E-02 4.58E-01 43 193 "RALGAPA1,NME5,KIAA1324,MARCH3,ZBTB10,RGN,DGKI,LONRF2,CLGN,CHI3L2,PNPLA8,ARHGAP24,CNNM1,FSD1L,SH3GLB1,FCGR1A,FGF13,FLT1,TRAF3IP2,ILDR2,FERMT2,NUDT21,LIX1,OLFM3,KCNK2,LAMA2,NDP,SFR1,PDE4B,PDGFRA,GNG2,NEK11,BAALC,KANK1,PRRC2C,KAZN,TEX15,TP53BP2,ZKSCAN5,ZBTB38,CA10,ZXDA,KCNAB1" Coexpression M412 Genes up-regulated in T reg: wildtype versus DICER1 [GeneID=23405] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.89E-03 1.00E+00 4.61E-02 4.58E-01 33 140 "CARMIL3,CLGN,IGDCC3,SIPA1L1,FAM135B,EGR3,ELN,ARMCX1,FGF1,JPH4,GRM5,ARHGAP19,DDX19B,IL6ST,ITPKA,KCND3,KCNJ4,MDGA1,CLDN11,PDYN,PMP22,FA2H,FAT3,PRODH,GALNT10,RASA3,SLC6A8,PDZD2,SATB2,ZIC2,NDRG4,FSTL5,CBLN2" Coexpression M2460 Genes downregulated in the postnatal day 3 pancreata with impaired function of GLIS3 [GeneID=169792]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.90E-03 1.00E+00 4.61E-02 4.58E-01 12 37 "SYT13,CHGA,RIMS3,SYTL4,NEUROD1,PAX6,PCSK2,PPP1R1A,SCG5,SLC2A5,SST,ABCC8" Coexpression M15187 Cluster d6: genes progressively down-regulated in WS1 cells (fibroblast) through 18 h after irradiation with high dose UV-C. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.90E-03 1.00E+00 4.61E-02 4.58E-01 12 37 "BCAR3,QKI,EPS8,AHDC1,MEIS2,PDGFRA,STRN3,PRRX1,PTK2,PUM2,ZMYND8,USP32P2" Coexpression 12097256-Table2 Human Skin_Wang02_42genes GeneSigDB 7.90E-03 1.00E+00 4.61E-02 4.58E-01 12 37 "APP,CD86,FOXN3,CSNK1E,EBI3,FCGR3A,PRRC2B,JAK1,ODF2,PROX1,SHMT2,AKTIP" Coexpression M6324 Genes down-regulated in untreated spleen: DUSP1 [GeneID=1843] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 7.93E-03 1.00E+00 4.62E-02 4.59E-01 40 177 "ACTN1,ADD1,ADD3,PITPNM2,USP28,GPR146,ARHGEF1,MAP4K4,SIPA1L1,HDAC4,TOX,KBTBD11,MBNL2,EIF4G1,PLEKHO1,EVL,RAPGEF6,GNAS,RAPGEF4,GSTT2,IL6ST,ITPKB,SESN3,PIK3C2A,PACSIN1,SIDT1,RGS10,SATB1,SELL,SHMT2,ST6GAL1,ST8SIA1,DZIP1,SLC14A1,TET1,TBL1X,TCF7,TCF12,ARHGAP9,TUBB2A" Coexpression M6814 Genes up-regulated in immature dendritic cells: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 7.93E-03 1.00E+00 4.62E-02 4.59E-01 40 177 "NDRG2,BEND6,OSBPL6,BCAS1,CRLF1,MYL6B,CNTFR,CSNK1E,CMTM5,USP6NL,DNM1,STAU2,PPARGC1A,DBF4,GPD1,PACSIN2,FRMD3,ARHGAP19,SLC6A17,LDLRAD3,SHC3,NACA,ALDH1L2,ANLN,ROGDI,RLBP1,RPL38,RPS6KA2,SLC2A5,TET1,SOX5,STAC2,TACC1,TIMP4,TMPO,TOM1L2,LMF1,SPIRE1,PCBP4,NELFE" Coexpression 15906272-Table5 Mouse StemCell_Greijer05_57genes_DownRegulatedbyHypoxia GeneSigDB 8.00E-03 1.00E+00 4.65E-02 4.62E-01 14 46 "ALCAM,SEPT7,COL4A5,YTHDC1,CASP8AP2,SMC2,PSIP1,KTN1,PAXBP1,HNRNPM,REV3L,TCEA1,TMPO,TPM4" Coexpression 16597596-TableS1-2 Human Leukemia_Wilson06_50genes_SigDifferentialClusterB1 GeneSigDB 8.00E-03 1.00E+00 4.65E-02 4.62E-01 14 46 "CDC42BPA,ANK3,ABCG2,TMCC2,MAMLD1,TSPAN5,OPTN,DMTN,PBX1,SPTB,COLGALT2,TAL1,UCHL1,ST7" Coexpression M8556 Genes up-regulated in A549 cells (lung cancer) upon expression of ASCL1 [GeneID=429] off a viral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.00E-03 1.00E+00 4.65E-02 4.62E-01 14 46 "SEMA6A,ADGRG1,CHGB,PPP1R16B,CALY,EDN3,RASA4,IGFBP1,SCG3,SYTL2,RET,SSTR1,SSTR2,SCG2" Coexpression 15906272-Table2 Mouse StemCell_Greijer05_57genes_DownRegulatedunderHypoxia GeneSigDB 8.00E-03 1.00E+00 4.65E-02 4.62E-01 14 46 "ALCAM,SEPT7,COL4A5,YTHDC1,CASP8AP2,SMC2,PSIP1,KTN1,PAXBP1,HNRNPM,REV3L,TCEA1,TMPO,TPM4" Coexpression 18006812-TableS1 Human Lymphoma_Piccaluga07_260genes GeneSigDB 8.05E-03 1.00E+00 4.68E-02 4.65E-01 45 204 "ADGRF5,SPARCL1,ANK2,APOC1,PLA2G4C,C1QC,IL33,DCLK1,CLU,ABI3BP,CP,ARHGEF10,DOCK4,FAM198B,PDLIM5,GABBR1,FERMT2,FAM107A,GUCY1A1,GUCY1B1,IRAK3,HNMT,KCNJ10,KCNMA1,LIFR,CCDC80,P2RY13,DDR2,PDGFRA,ENPP2,PMP22,PRRX1,CCDC102B,RPE,WLS,SLC1A3,RGL1,TJP1,TLR4,TNS1,TPM1,NPL,FLRT2,ADAMTS9,TMEM163" Coexpression M5951 "Genes up-regulated during production of male gametes (sperm), as in spermatogenesis." MSigDB H: Hallmark Gene Sets (v6.0) 8.07E-03 1.00E+00 4.69E-02 4.66E-01 32 135 "TKTL1,CNIH2,MAP7,CLGN,CHRM4,IP6K1,DCC,SNAP91,CLVS1,GAD1,DBF4,PCSK1N,GRM8,AGFG1,HSPA1L,HTR5A,PACRG,SCG3,DDX25,NEFH,NOS1,SPATA6,SEPT4,RAD17,ZC3H14,HSPA4L,SCG5,SLC2A5,SLC12A2,SIRT1,TSN,IFT88" Coexpression 20460173-ImmPortCytokineReceptors Human Immune_Kong10_308genes_ImmPort_CytokineReceptors GeneSigDB 8.13E-03 1.00E+00 4.72E-02 4.69E-01 63 303 "ADCYAP1R1,ADRB2,NR0B1,LGR5,NRP2,BMPR1B,CRLF1,CNTFR,CSF1R,CSF2RA,CSF3R,PLXNA4,SDC3,CX3CR1,NR1D2,EDNRA,EDNRB,EGFR,PLXNC1,CALCRL,TUBB3,FGFR1,FGFR3,FLT1,GHR,BRD8,PRLHR,GPR17,MCHR1,GPER1,NR3C1,PTGDR2,HNF4G,IL6R,IL11RA,LIFR,OPRL1,OXTR,PLXNB1,PLXNB3,PPARA,PTAFR,PTH1R,ROBO1,ROBO2,RORB,LGR4,RXRA,RXRG,TNFRSF19,IL17RB,SSTR1,SSTR2,TACR1,ROBO3,TEK,TGFBR3,THRA,TIE1,NR2E1,TNFRSF1B,NR2C2,VIPR2" Coexpression M11891 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.14E-03 1.00E+00 4.72E-02 4.69E-01 79 393 "INTS2,TAOK1,AMPD2,ASPH,ATP1A1,ATP2A2,ATP2B1,MTMR9,CAMK2D,CCNT1,SOCS6,SLIT2,NMT2,MAP4K4,NIPBL,FAM149A,LETMD1,LRIG1,VCAN,MATR3,DDX46,G3BP2,DUSP9,TSPAN5,APH1A,EIF4G1,MFSD10,EPB41L1,RACK1,SYNCRIP,SGIP1,NOP56,RAPGEF6,USP19,RND1,GLDC,GLS,RAPGEF1,HNRNPK,SCIN,SMAD1,ZFYVE27,PPM1L,MTR,SLC11A2,PC,ENPP2,PIK3R1,PRRX1,SLC22A23,GON4L,C1orf109,OXR1,KCTD17,MCMBP,AP1AR,ASRGL1,HSPA4L,KIF21A,FAM102A,URGCP,SLC6A8,SLC12A2,SLC14A1,SLC20A2,ZKSCAN3,SMARCA4,KIF13A,FAIM2,PDZRN3,MLST8,CNTN2,TRIM2,ZMAT3,ZNF106,TPM1,SLC35A4,DHX33,WIPF2" Coexpression M16955 Genes whose promoters display lower levels of histone H3 trimethylation mark at K27 (H3K27me3) in hepatocellular carcinoma (HCC) compared to normal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.26E-03 1.00E+00 4.79E-02 4.75E-01 49 226 "PCDHGB4,CRMP1,PDE4DIP,PPP1R16B,KATNAL2,FRMPD4,DTNA,GOLT1B,USH1C,RCAN2,ZNF461,TMEM132C,CHST15,ATP8A2,CPLX2,PCDH11X,INSM2,CNTRL,RAPGEF4,GRIK2,CELF3,SHISA6,NTRK3,NUCB2,PCDHGC3,NOMO2,ANLN,PROX1,ZFHX4,STK32B,KCNIP1,SCN8A,CHD9,BTBD3,NBPF1,ANKRD12,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,TMEM121,TUB,NSD2,POLR3H,ADAMTSL3" Coexpression M4466 Genes up-regulated in comparison of neuthrophils versus monocytes. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "NLGN4X,KIAA1324,KIAA1614,NOL4,CA4,CBLN1,RGN,TMEM257,CLCN4,RIMS2,SNAP91,PHC2,EPHB1,ETV1,DLC1,SCARA3,FOXM1,SIGLEC8,GLRB,GRIK2,CIT,PTGDR2,KCNA4,KCNJ5,LIFR,MAP2,KITLG,BCO1,NRCAM,OPHN1,NECAB2,MAGEL2,PYGM,RGS4,RLBP1,LGI2,OGDHL,SOX3,NPAS3,MCF2L,TJP1,PARD3,VGF,LAMP5" Coexpression M9430 Genes up-regulated in T reg: in vivo versus in vitro. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "FZD9,NR0B1,SORCS2,SRPX,PCDH10,AMPD3,SEMA4G,CACNB2,CAPN3,EVI5L,PLEKHB1,HECTD1,FAM169A,PLCXD3,DAPK1,ZEB2,ELN,OLIG2,KCNMB2,APOPT1,PHYHIPL,GRIA4,SCRG1,INSM1,KCNK1,MEF2C,MMP16,MYT1,NPY,CNTN3,PAX6,RELN,PTPRG,SCN7A,MYT1L,SOX11,IQSEC2,CLSTN2,ITPRID2,SEPT3,IL34,CA14,EMX2OS,SEMA3B" Coexpression M7817 Genes up-regulated in amplified multipotent progenitors versus common dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "PLEKHH1,DOC2A,ANXA7,MARK4,RAB29,FBXO7,LY86,FHL5,IQCK,SLC35F1,MAML1,ZBTB24,EBI3,RASA4,ADGRV1,PPP1R1B,AKAP3,NBEA,PNMA2,OS9,NEGR1,LMO2,MPP2,MYH6,MYL3,NPR2,ST8SIA5,PMP2,DPF2,RGS7,RNASEL,PNMA8A,RPE,FAM81A,SNRPN,PBLD,NACAD,PLCB1,TAL1,VWC2,WASHC4,DDHD1,SPHK2,AMN1" Coexpression M6389 Genes down-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "TTYH1,ASIC1,ADCY5,MARCH4,AMPD2,ASPA,DACT3,ATP2A2,C1orf52,CLGN,SLC24A2,AATK,YTHDC1,DNAJC6,CD99L2,ACOT8,ELN,DMTN,EPHA5,EYA1,CRCP,GLUL,ADAMTS8,PTGDR2,C2orf72,KCNK3,MEST,MYH7,GPR88,KCNK10,PDE3B,TMIE,PNMA3,POLR2F,SLC25A41,RFX2,SNX22,SMOC1,TAC3,PSD3,TPM3,VIPR2,DPF3,PRRT4" Coexpression M9317 Genes up-regulated in marginal zone B cells versus day 40 germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "RNF157,CNIH2,PPFIA1,KCNAB2,USP37,RASL11B,JAZF1,PRMT9,BAIAP3,CAPN3,CD38,CLCN3,RTTN,ANKRD44,HEPH,KIAA0753,SACS,RASGRP1,FRY,CALCRL,SUCO,ZNF512,FYN,CHL1,DNER,SRCAP,SPACA9,GYG1,PADI2,INPP5B,JAK1,NASP,NUCB1,PDE3B,PIK3R1,PPP3CA,PRKACB,SKOR1,RNASEL,CDK5RAP2,ITGB3BP,NR2C2,TMPRSS5,USP1" Coexpression M4426 Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus naive B cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "MARCH3,BCL2L2,BCL7A,BTK,DDR1,USP2,LARGE1,CLCN4,LY86,CNR1,COL9A2,HDAC9,MYEF2,TIAM2,RHOBTB1,SCML2,CORO2B,CHL1,GATM,RAB30,GPM6A,IRF8,MEF2C,MID1,CD200,CDK14,STRN3,HYDIN,MTMR10,RIPOR1,ZNF532,TMEM156,CSRNP3,SCN3A,CNKSR2,SLC12A2,SOX5,IDI2-AS1,PEG10,MTCL1,DNMBP,TCF4,VAV2,DPF3" Coexpression M5532 Genes up-regulated in comparison of neutrophils versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "SERPINA3,APAF1,CA12,LRRFIP1,SIPA1L1,ARHGEF4,DOCK4,SLC12A6,ERBB2,SEC24B,C1orf61,SORBS1,B3GAT1,SARAF,GABRA3,GAD2,GRIA2,GRIK5,KCNB1,KIF5A,L1CAM,MARK3,MSRA,PFKFB2,PFKFB3,SPATA6,SNRK,RIPOR1,DCUN1D2,SLA,BTBD7,SMARCD3,MBD5,TMCC1,MYO16,NSFL1C,SEMA4A,PDLIM2,AGTPBP1,HEY1,CDK20,FLRT1,SLC30A3,MPPE1" Coexpression M3182 Genes up-regulated in comparison of IgD+ B cells versus IgD- B cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "C1QTNF1,AMT,DGKD,CDK10,ARSF,BCL7A,MTMR2,WASF1,NEURL1,ARHGAP22,CPS1,CNTNAP2,KIAA0040,B3GAT3,MED12,PLEKHA1,EPB41L2,EVL,SARAF,SYT17,SESN1,POLL,CNTRL,IDH3B,IGSF1,MBNL1,MMP17,PCDH9,PENK,FAM120C,RNF220,SATB1,SH3BP2,SLA,LIMS2,KDM4D,ZNF334,ZNF415,FCHO1,MAPK8IP3,MPRIP,CNTN2,AMACR,SF1" Coexpression M9879 Genes down-regulated in CD4 [GeneID=920] T cells: NRAS [GeneID=4893] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ADD3,BCAR3,APAF1,PLA2G4C,CLCN3,NMT2,ABCG1,JAKMIP2,DYRK1A,EBF1,FRY,DCTN4,VPS13B,AMZ2,STAG2,GALC,ACSS1,BRD8,SPIN1,PRUNE2,PSIP1,METTL21A,PBX1,RETREG1,GPSM2,FTO,PRKAB2,PTPN13,GTDC1,SELL,SH3BGR,RCOR3,PDZD2,TRERF1,ZC3H4,PLCB1,C12orf76,ZFAND5,RNF103,MDH1B,MVB12B,MARCH8,RSPRY1,SENP7" Coexpression M3622 Genes down-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "FZD9,MARK4,NCOA1,P2RX6,LRBA,SLC22A6,MYL6B,EFNA3,TENM1,ELAVL4,STX2,MRVI1,SEMA6C,DKK3,GAA,RUNDC3A,GPM6B,KAT7,KLF12,IGFBPL1,INPP1,ITGAV,KCNK3,MATN3,MEST,MSI1,MYT1,NRCAM,PENK,PGAM2,PHKG1,NKAIN1,RAD52,RGS4,MYH14,RTN1,RYR3,SIRT2,ROBO3,NACC2,RBFOX2,LGI4,ZNF23,DPF3" Coexpression M8429 Genes up-regulated in CD8 T cells: stem cell memory versus effector memory. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ABCF1,ACADM,ADCY2,DOC2A,ANXA7,PROM1,CACNB4,CDC25B,CNTN1,COL4A5,DBN1,ELMO1,KIAA0753,TOM1,PLXNC1,EPS8,F8,CAMKK2,GHR,MSL3,GYG1,IPO5,KITLG,MSR1,ZNF92,PIK3CD,PPARA,LRRN3,PPP3CA,PSMD13,CNKSR2,ST8SIA1,SNAP25,SNCA,ZNF423,MPRIP,AJAP1,ARHGEF9,VPS13A,TBL1X,MGRN1,KAT6B,METTL3,INTS3" Coexpression M9571 Genes up-regulated in T conv from: peripheral lymph nodes versus thymic precursors. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "MADD,ARRB2,ATP2B1,ST3GAL5,THSD7A,ADGRG1,ZBED5,C2CD2,RASSF2,RHOBTB1,SEC16A,ING4,ENO2,EXTL1,DLC1,CHST15,CAMSAP1,GLDC,ADGRA3,GRB10,OXTR,PFKFB3,PIK3CD,SMOX,PTCH1,TUG1,RAP1GAP,UBR7,RGS3,RPE,CASC3,GALNT10,MRAS,SGK1,EPN2,PALLD,ANKRD28,CAMSAP2,FBXW11,TBL1X,SYNE1,NACC2,TTC3,ZFAND5" Coexpression M3171 Genes up-regulated in comparison of germinal center B cells versus memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "CDC7,SNX30,ZNF608,TXNDC16,ATP2A2,CAMK2D,CD81,ARHGAP33,MAP4K4,LRIG1,DBI,BLOC1S6,DMD,KLHL5,TUBA1B,TUBB3,AFF2,PSRC1,TUBA1C,RNFT2,BACH2,HNRNPK,IRF8,LMO2,MAP2,MYBPC1,AMZ2P1,CHAMP1,ZNF827,SUGCT,NCBP3,SFPQ,ASRGL1,SGK1,SCG5,SYBU,CCDC88A,PEG10,APOM,SYNE2,TACC1,DDHD1,TUBB2A,USP32P2" Coexpression M4015 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ALDH7A1,KIF1A,BCL2L2,CAMK2D,CCK,C1orf52,CD81,CRYBB1,NCOR1,ARMCX4,ABI1,PDCD6IP,RABEPK,ETV1,PCYOX1,AGAP3,CGREF1,GK,KAT7,HAPLN2,ITPKA,PIK3AP1,LRP1B,COMMD5,IDNK,PDPK1,PENK,PIK3C2A,MAPK3,CYBC1,PTX3,RPS6KA2,AP1AR,FAM214B,CAMTA2,DDHD2,PDLIM2,FBXW11,SYNE1,TIAM1,GORASP1,SPHK2,MRPL47,SNX14" Coexpression M8425 Genes up-regulated in B lymphocytes: systemic lupus erythematosous (SLE) versus healthy. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "PROM1,CBLN1,CCNT1,CDH8,CHI3L2,KIAA1549L,CS,FEZ2,PLCH2,DNAJC6,PLEKHM1,ELMO1,LYPD1,SEMA3D,TESK2,GFRA1,TOX3,MSL3,GYG1,HSP90AA1,PACRG,MBD1,MYO5A,NEFH,NELL2,POLR2F,LRRN3,MAPK9,PSMD13,RNH1,RPE65,SCN2B,BTBD3,MYH15,VPS13A,PLCB1,ANKRD12,MTCL1,TBL1X,SATB2,TRPC1,TRIM9,ST7,CERS6" Coexpression M8385 Genes down-regulated in CD4 [GeneID=920] T cells: untreated versus TGFB1 [GeneID=7040]. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ACHE,AP2A2,CDC14B,HCN2,CACNG1,CDH8,CPS1,SPOCK2,EDNRB,RCAN2,EPS8,REEP2,PTK2B,PRELID3A,RND1,LPAR4,JAK2,KCNJ9,KCNJ10,MAP2,AFDN,SAMD14,NELL1,NEUROD2,NHLH1,RGS12,RLBP1,EMID1,EPN2,SLC12A4,IGSF9B,ZCCHC24,NPAS3,DDN,SYN1,ASTN2,MTCL1,KIAA1107,IQCE,CDH22,THRA,TMOD1,METTL3,ZNF177" Coexpression M8303 Genes down-regulated in naïve T cells: CD4 [GeneID=920] versus Va24- NKT. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ABR,ASIC2,ADD3,BIN1,CDC42BPA,PLA2G4C,ARSE,MARCH3,RGS9,CDC25B,CDH2,DLGAP1,ASIC3,SEC31B,SNAP91,DMPK,OPTN,SORBS3,MRNIP,SRPK3,RASGRP2,FCGRT,FGFR1,TRAF3IP2,DISC1,USP19,STARD3,GRIK3,KAT7,C2orf72,IL11RA,ADAM11,AFDN,NUMA1,OCRL,PLCD1,PYGM,SCN7A,FAM168A,FAM189A1,THRA,TPM2,ZKSCAN5,TUBB2A" Coexpression M8352 Genes down-regulated in atherosclerosis macrophages: anti miR-33 versus untreated. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "BBOX1,CASK,PLA2G4C,ALDH7A1,MAP7,LRIG1,ARHGEF10,VCAN,ERC2,CCDC144A,DGKB,RASGRP1,DENND4A,SIRPB1,FOXF2,AFF2,ATP6V1H,CHL1,GRM5,GUCY1A2,PACRG,NCF2,SLC11A2,PCSK5,PGAM2,POU3F4,LRRN3,PROX1,PTPN13,PTPRZ1,PLEKHB2,KCTD17,SELL,GALNT10,SLA,PALLD,EPB41L3,NXT2,RGL1,ZFR2,SYN2,SYT1,TP53BP2,FXR1" Coexpression M7379 Genes up-regulated in the activated CD4 [GeneID=920] T cells (48h): control versus IL-12 and IL18 [GeneID=3606]. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "RBM10,RNF157,KCNAB2,EPB41L5,APLP1,CDC14B,PDXK,CADM3,HAP1,VSTM2A,ENTPD6,CSF2RA,USP6NL,ACOT8,TLR7,F5,PTK2B,NELFCD,ERGIC3,STAG2,GRIN2D,RBPJ,KCNC2,KCND1,L1CAM,MIA2,SESN3,MYO5A,NPPA,PPP2R5C,PPP3CC,MAPK7,PTPRG,PTPRZ1,RAD51D,KANSL3,COBL,WDR7,IL34,DNAJC12,TOM1L2,ZFP41,DPYSL5,LMAN2L" Coexpression M4606 Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "SHTN1,ARRB1,ZSCAN18,ST3GAL5,CHN2,CRY2,FEZ2,CYBB,GPRASP1,ZFYVE16,SIRPA,LPAR6,STX2,FCGRT,LILRB4,GSN,SLC2A6,HNMT,IRF8,MSL1,P2RY13,NELL2,SLC11A2,LRP12,PTPRE,C1orf54,RNASE1,RTN1,SLC1A3,SLC2A5,CCDC88A,ZNF415,TEX2,RGL1,KANK1,TCF4,TCF7,ZNF34,NACC2,BEX4,NPL,TTC3,ITM2C,NLRP3" Coexpression M5145 Genes up-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. major. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "ACLY,ADORA3,PPFIA1,FAM131A,ARRB2,SLC4A4,CA4,NRXN3,ELMO1,SMG7,SACS,TMCC2,E2F6,FEM1B,RRAGB,FGR,FOLR2,FYN,TCERG1,GRIN1,IFI16,IL12A,NOVA2,PDE1B,PPP3CA,PSD,PTK2,QDPR,RGS10,ATXN1,SLIT1,MAPKBP1,KDM4B,CLUAP1,CAMTA2,SEPT8,MTCL1,TAL1,FAM208A,AHCYL2,TP53BP1,CDK20,TFIP11,INTS3" Coexpression M8173 Genes down-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "PRX,ATP2B1,SCAPER,LOC730101,RCBTB2,PLAA,TPP1,WHRN,OSBPL3,IPCEF1,PDE4DIP,GREB1,RABGAP1L,MED12,EDN1,EBI3,LPAR6,EIF5,MRNIP,LRRC17,EZH1,EVL,ALDH1L1,PRUNE2,GRIK4,IDH3B,MTR,NFIX,SLC11A2,P2RX7,EXOSC10,MINDY2,PTPA,CYBC1,MYH14,SCG5,DZIP1,EPB41L3,PHLDB1,PCDHGA9,TMEM151B,TRIO,NAV2,UBE3B" Coexpression M6803 Genes up-regulated in T reg: wildtype versus FOXP3 [GeneID=50943] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.35E-03 1.00E+00 4.79E-02 4.75E-01 44 199 "SLC25A25,HECW2,ALCAM,APBB1,SPAG9,CLDN10,RTTN,AKAP12,INTS1,PITPNC1,SNX29,PLEKHO1,HSPA12B,AMZ2,FGF13,BAIAP2,GAB1,PRRC2B,ADAMTS6,LRRC75A,DIPK1A,KCNB1,L1CAM,PIK3AP1,MXI1,MYH6,MYO9A,NF1,NNAT,PCMT1,RETREG2,MAPK9,RAP1GDS1,ZNF821,RASA3,LGI3,ARFGAP1,MAST1,KDM3A,SPTAN1,RGL1,KIAA0930,EMSY,SSPN" Coexpression M420 Genes down-regulated in dendritic cells: immature versus mature inhibitory infected with L. monocytogenes. MSigDB C7: Immunologic Signatures (v6.0) 8.42E-03 1.00E+00 4.83E-02 4.80E-01 30 125 "AMPH,TMEFF1,CDK5R2,BTRC,CLU,SLC35F1,FAM169A,CTH,TBC1D5,USPL1,TMEM164,GAP43,AHDC1,C1QL4,FRMD3,RBPJ,KLHL23,PIK3AP1,ALDH1L2,GNG2,PLXNB3,DRAM2,MARCH1,RGR,LGI2,RTKN,MESP1,TNNT1,VLDLR,PROCA1" Coexpression M4342 "Up-regulated genes in hepatocellular carcinoma (HCC) subclass G6, defined by unsupervised clustering." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.45E-03 1.00E+00 4.84E-02 4.81E-01 18 65 "ACTN2,C1QTNF3,CBR1,SULT4A1,GREB1,FBXL5,RHOBTB1,DYNC1I1,NPR2,SEPT4,ACSS3,SLC22A4,TMCC1,ACSL6,VSNL1,SLC13A3,ATP6V0E2,MARCH8" Coexpression 17894856-SuppList4 Human Breast_Yu07_298genes GeneSigDB 8.48E-03 1.00E+00 4.86E-02 4.82E-01 46 210 "SRPX,CDC42BPA,CASK,CCNT1,SEPT7,SRSF11,SOCS5,APPL1,PARD6A,NTM,DLG3,CASP8AP2,EDNRA,PLXNC1,SRRM1,FGFR1,TRAF3IP2,PCDH17,FERMT2,CIT,FICD,MAP4K5,WIF1,MATN3,AFDN,MPP2,NCAM1,PDE4B,PDGFRA,CYTL1,MAPK9,MAPK10,RGS3,RGS4,MRPS18A,SFPQ,CLSTN1,SHANK2,PDLIM2,TCF4,ZFPM2,ITGB3BP,TLR4,PARD3,TNS1,TRPC1" Coexpression 14768006-SuppTable5 Human Breast_Kim04_283genes GeneSigDB 8.48E-03 1.00E+00 4.86E-02 4.82E-01 46 210 "NME5,OGT,GPC2,KALRN,SPAG9,CLDN10,CCNT1,CLTC,MAP4K4,SLC4A7,CHD1L,CPS1,CHD5,DBI,KIAA0753,DMD,EIF4G1,TUBB4A,FCGR3A,DLL3,MPP6,SDCBP2,IQGAP2,CIT,MATN3,MBD1,MBP,AFDN,MTTP,NASP,NRCAM,OPCML,SNX10,NLE1,RGS4,SH3GL3,CLSTN1,SEPHS1,SLC12A2,NAXD,SMARCD3,ARHGEF9,TPM3,TRPC3,TTC3,ZNF610" Coexpression 12734205-TableS1 Human Ovarian_Wood03_346genes GeneSigDB 8.55E-03 1.00E+00 4.89E-02 4.86E-01 60 287 "ABAT,AS3MT,ACTN1,ADORA1,C1QTNF3,SPARCL1,FGD2,APC,TMEFF1,ADAM23,PRC1,CBR1,CLU,NCOR2,CTH,USP6NL,RIPOR2,DAPK1,DPH1,SORBS3,ETV1,CD320,FGF12,FGF13,UBE2E3,CRCP,RAPGEF4,KIF3A,SCRG1,MATN2,TM6SF1,MEST,POC1B,MMP16,CCDC80,NASP,NEFH,NOVA1,NTRK2,CHAMP1,PKD1,FTO,FA2H,PROX1,OCIAD1,QDPR,RFX5,SEC14L1,SCG5,ABLIM3,NAXD,BEX1,SSTR1,TMEM150C,ATP11A,TPM2,AMOT,VAV1,TCEAL7,FIP1L1" Coexpression M6861 Genes down-regulated during B lymphocyte differentiation: pre-B I versus small pre-B II. MSigDB C7: Immunologic Signatures (v6.0) 8.58E-03 1.00E+00 4.91E-02 4.87E-01 29 120 "CNTNAP1,NCOA1,KYAT1,CERS5,DGKI,DCAF8,ACY3,C2CD2L,SGSM2,SEZ6L2,EEF1A2,CALCRL,CORO2B,CAP2,IQCG,MEGF10,TMEM8B,GPM6B,PRDM5,ZHX1,KCNH1,NCAM2,PDE1C,SERPINI1,PURG,FAM120C,ZKSCAN3,SMOC1,ZDHHC20" Coexpression M11787 Down-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.63E-03 1.00E+00 4.93E-02 4.89E-01 11 33 "SRPX,CNTNAP1,SLC4A4,C2orf88,ATG4C,ATXN2L,MXI1,EXD2,GSTCD,SGK1,USP22" Coexpression 15980968-Table3a Human Brain_Bandres05_42genes GeneSigDB 8.63E-03 1.00E+00 4.93E-02 4.89E-01 11 33 "ACTN1,ADRA1B,COL9A1,ECM2,GABRA2,GPR37,MSR1,RGR,RIT2,ICAM5,SLC30A3" Coexpression M1489 "Genes required for CTNNB1 [GeneID=1499] activity in DLD-1 cell (colon cancer with APC [GeneID=324] deletions), based on shRNA screen." MSigDB C2: CGP Curated Gene Sets (v6.0) 8.63E-03 1.00E+00 4.93E-02 4.89E-01 11 33 "TAOK1,CSNK1E,CSNK1G3,SRPK3,PTK2B,FER,CAMKK2,GABRA3,DCLK2,KSR2,SYT11" Coexpression 18318837-TableS2 Human MesenchymalStemCells_Yamamoto08_387genes GeneSigDB 8.65E-03 1.00E+00 4.94E-02 4.91E-01 56 265 "VWA5B2,KCTD16,AMH,SEMA7A,PI16,VAT1L,SLC7A14,RNF182,CACNA2D1,PRC1,CDH18,HAPLN1,NTM,DLX1,DRP2,EPHA5,EXTL1,SCARA3,FOXM1,GABRA2,B4GALNT1,SRRM4,KIRREL3,LOXL3,PLCD4,GRIK2,CIT,ATOH8,HAS2,SCRG1,SCIN,KCNK3,MSRA,HS6ST3,NPTX1,NRGN,PDE1C,PENK,ANLN,PLCL1,NDUFS7,PTN,PTPRB,RGS4,TRIM46,NLGN1,ZNF365,SSTR1,TCF7,TEK,HHIP,GORASP1,FMN2,PLPP4,LYPD6,SLC30A4" Coexpression M6813 Genes in the expression cluster 'HSC Shared': up-regulated in hematopoietic stem cells (HSC) from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.68E-03 1.00E+00 4.94E-02 4.91E-01 54 254 "EMILIN3,ACTN2,APBB2,VAT1L,IGDCC4,CHN1,SLIT2,NRXN3,NRXN1,SULT4A1,SLC35F1,SOCS5,ARHGAP32,PITPNC1,LYPD1,SV2A,ARNT2,SEMA3D,EFNA3,ETV1,GTF2IRD2,IQGAP2,KCNMB4,LPAR4,KIF5A,NFIX,NTRK3,PDE4B,CDK14,CDIP1,PPP2R5C,PRKACB,LRRC49,DEF8,PYGM,RBBP6,BAALC,SGSM1,LRRTM4,PRCD,PPP1R9A,MYCBP2,MPRIP,SEPT3,SYT11,SYN2,ROBO3,CAMTA1,TCF4,ZMYND8,FAM181B,CCDC136,VLDLR,TRIM9" Coexpression 16280042-GeneList Human Breast_Pawitan05_64genes_prognosisGenes GeneSigDB 8.68E-03 1.00E+00 4.94E-02 4.91E-01 15 51 "SPARCL1,IGDCC4,RUNX1T1,PRC1,ADGRG1,SLIT2,DNM1,IGF1,ANLN,FXYD1,PTN,SCN7A,ZCCHC24,STXBP1,FLRT2" Coexpression 16168083-Table1 Human Sarcoma_Henderson05_54genes GeneSigDB 8.68E-03 1.00E+00 4.94E-02 4.91E-01 15 51 "ABAT,COL9A1,COL9A2,COL11A2,GPD1,GRM1,MAPT,MATN3,NINJ2,PLIN1,PRKCB,SNAP25,CBX5,VSNL1,AP3B2" Coexpression M8128 Genes down-regulated in MKN45 cells (stomach cancer): control versus H. pylori LPS. MSigDB C7: Immunologic Signatures (v6.0) 8.72E-03 1.00E+00 4.94E-02 4.91E-01 37 162 "ALCAM,ANK3,USP28,INSYN2B,HAP1,CAMK2D,BRSK2,LRBA,PPT2,CLTA,COX4I1,CORO2B,FGF1,SEMA6C,B4GALNT1,GNG3,CPT1C,ITGA7,C2CD4C,LRRC4B,NRGN,SPATA6,IRX1,VSTM2L,PRKCB,RASGRF2,GTDC1,RGS3,SARS,LMBRD1,WDTC1,CAND2,SSTR2,ST5,PDLIM2,TRPS1,FAM181A" Coexpression M8773 Gene expression signature of vascular invasion of hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.85E-03 1.00E+00 4.94E-02 4.91E-01 6 13 "ZNF687,AMPD3,CSF3R,OGG1,RAB39A,RYR1" Coexpression 19549311-SuppTable2-PAM Human Leukemia_Zangrando09_15genes GeneSigDB 8.85E-03 1.00E+00 4.94E-02 4.91E-01 6 13 "ESYT2,AK2,ZEB2,EBF1,HIPK3,MEIS1" Coexpression 15326482-Table3b Human Liver_Nakagawa04_14genes GeneSigDB 8.85E-03 1.00E+00 4.94E-02 4.91E-01 6 13 "DPYSL2,MEIS1,BEX1,TCEA1,BEX4,TRIM9" Coexpression M6139 Genes located outside the microdeletion region in 22q11 which were differentially expressed in the same manner both in hyppocampus and prefrontal cortex. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.85E-03 1.00E+00 4.94E-02 4.91E-01 6 13 "CDK5R1,BSN,ZNF445,B3GAT1,LINC00461,SLC17A7" Coexpression 15167912-Table2 Human BoneMarrow_Liu04_20genes_thalidomide GeneSigDB 8.85E-03 1.00E+00 4.94E-02 4.91E-01 6 13 "TMEFF1,GAD2,MSTN,MSR1,PTHLH,CLASP2" Coexpression M19202 Genes whose CpG islands became hypermethylated in breast progenitor cells pre-exposed to estradiol [PubChem=5757]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.85E-03 1.00E+00 4.94E-02 4.91E-01 27 110 "RNF150,ZNF687,PDZD4,PRX,BMP7,KIAA0408,DGKG,GOLT1B,VPS13B,MEX3B,ARPP21,GDF1,OS9,ZNF496,LRRTM1,A1BG-AS1,MXI1,POLR2F,PTPRG,IL17RB,ERBIN,TTBK2,CLASP1,ZNF384,METTL3,RPRM,EMSY" Coexpression M1696 Genes up-regulated in the Ad/AH cells (adenocarcinoma) engineered to stably express the Epstein-Barr virus (EBV) gene EBNA1. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.85E-03 1.00E+00 4.94E-02 4.91E-01 27 110 "LGR5,ARHGDIA,SCARB1,CHN1,CLU,MAML1,EEF1A2,ABI2,EIF4G1,SRRM1,FGFR3,FHL1,UBE2E3,TRIM16,NCKAP1,TUBGCP4,GLUL,GNAS,INPP1,ITGAV,NEFH,NELL2,NFE2L2,HIRA,WIPF1,SF1,TUBA1A" Coexpression 15604209-Table2a Human Uterine_Luo05_83genes_2Hr GeneSigDB 8.90E-03 1.00E+00 4.94E-02 4.91E-01 20 75 "MRTFA,ADGRB2,DST,RAB29,NCOR2,PHC2,LRRC23,NEURL4,BRD8,GUCY1A2,MAP4K5,LMO2,NEFM,OLR1,GPSM2,POLR2F,POU6F1,PKN2,PSMA6,RBBP6" Coexpression M1578 Genes down-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.91E-03 1.00E+00 4.94E-02 4.91E-01 47 216 "ADRB2,SEMA6A,BCAR3,PKP4,CFLAR,CA4,THSD7A,SCARB1,ADGRG1,JAM2,MYRIP,CREM,ABCG1,PITPNC1,RCAN1,RASA4,LPAR6,CD320,NRN1,FLT1,TRIM16,PCDH17,RND1,RAPGEF4,FAM107A,ICA1,LMO2,SMAD1,PDE2A,SSH1,SCHIP1,PTPRB,PTPRE,RNASE1,BAALC,RPS6KA2,SEC14L1,ST6GAL1,SYBU,ABLIM3,MCF2L,DOCK9,TEK,TIE1,TNFRSF1B,TPD52,ADAMTS9" Coexpression M11238 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.98E-03 1.00E+00 4.94E-02 4.91E-01 49 227 "RALGAPA1,SEMA6A,MADD,CFLAR,BMP7,DST,CD81,CDC27,COL4A5,SEC31B,ABCG1,GSDME,ABCC5,LPAR6,EPB41L2,RACK1,FGFR3,ERAP1,SEPT9,GRB10,HNMT,AGFG1,IFI16,LIMS1,VWA5A,MEIS1,NME4,ZNF827,PDE4D,ZNF655,CDIP1,SYTL2,PTPN13,PTPRE,PTPRN2,RFX2,RFX5,RGS12,DGLUCY,ATXN1,CHD9,ARHGEF40,SNRPN,UNC5B,PSD3,TK2,MICAL1,ITM2C,FRMD6" Coexpression M381 Genes down-regulated in dendric cells: untreated versus LPS and anti-CD40. MSigDB C7: Immunologic Signatures (v6.0) 9.03E-03 1.00E+00 4.94E-02 4.91E-01 39 173 "ACADM,ADORA3,MTA3,AMPH,APAF1,CD86,CD38,ADGRG1,OSBPL3,SRGAP3,CD99L2,NEK6,ATP8A2,HPGDS,B4GALNT4,GPR34,IRAK3,RBPJ,ITGAV,MATK,NUCB2,GNG2,SEPT4,PRKACB,SYTL2,ZYG11B,RGS10,FOXRED2,SH3BP2,FNDC3A,ST8SIA1,SLC20A2,ANKRD28,ARHGEF12,TGFBR3,TJP1,SSBP2,LAT2,TMEM163" Coexpression M6716 Genes up-regulated in endothelial cells: B. burgdoferi versus IFNG [GeneID=3459] and B. burgdoferi . MSigDB C7: Immunologic Signatures (v6.0) 9.03E-03 1.00E+00 4.94E-02 4.91E-01 39 173 "NDRG3,MTA3,TBC1D14,KCNAB2,NCOA1,N4BP2L1,BACH1,GPR146,NFS1,PLEKHM1,ING4,PLEKHO1,SLC43A2,FCGRT,FOXO3,GALC,GPR162,HPGDS,PRUNE2,COQ10A,KHK,SCAMP5,RETREG1,PTPA,TMEM206,PTGR2,SEC14L1,MYO18A,ELMO2,ATF7IP,TRERF1,ZCCHC24,KIF21B,FNBP1,IQCE,TIAM1,TPM1,LAT2,SLC38A1" Coexpression M6328 Genes down-regulated in spleen from wildtype mice: control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 9.03E-03 1.00E+00 4.94E-02 4.91E-01 39 173 "ACTN1,ADD1,PITPNM2,USP28,GPR146,ABCG1,TOX,KBTBD11,KMT5B,PLEKHA1,PLEKHO1,RCSD1,RACK1,CHST15,EVL,SARAF,RAPGEF6,SESN1,GNAS,RAPGEF4,GSTT2,ELOVL5,IL6ST,ADAM11,SESN3,SLC11A2,RETREG1,PACSIN1,SIDT1,ZYG11B,RGS10,SATB1,ST6GAL1,TET1,TBL1X,TCF7,ARHGAP9,TGFBR3,SSBP2" Coexpression M2021 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 2. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.09E-03 1.00E+00 4.94E-02 4.91E-01 22 85 "CLK4,NR0B1,OGT,FUBP1,CAPN3,CLGN,RBM39,CDON,AASS,ELN,GCNT2,GNAO1,PAXBP1,NPTX1,PIK3CD,EPB41L4B,RELN,MEG3,SFPQ,NAPB,SOX3,SOX5" Coexpression 18803589-Table2 Human Viral_Pazienza08_88genes GeneSigDB 9.09E-03 1.00E+00 4.94E-02 4.91E-01 22 85 "APOC1,APP,SYNJ2,MAP4K4,PUM1,EDN1,HIPK3,EGFR,RPS6KC1,FGFR3,CAMSAP1,DKK3,GRB10,PAXBP1,PDGFRA,POLG,ACER3,FNBP1,SPP1,TCF7L2,TTC3,SLC38A1" Coexpression M16128 Genes up-regulated in MFCF-7 cells (breast cancer) by exogenous HG1 [GeneID=2688]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.09E-03 1.00E+00 4.94E-02 4.91E-01 22 85 "SPARCL1,LGR5,ST6GALNAC3,GABRA4,GLYR1,PRLHR,PCLO,C2orf72,IL6ST,SFXN5,NFYA,NHLH1,NOS1,NKAIN1,SNCA,SPATA7,PEG10,SYT5,TK2,ZFP91,PRRT1,TSC1" Coexpression M4869 Genes down-regulated in comparison of NKT cells versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ASPHD1,ACADM,CSMD3,DOC2A,GPR146,PRC1,LDB2,CHM,RGS6,GALNT9,CST3,TIAM2,CPEB2,SORBS3,VPS13B,RASGRP2,FDFT1,SALL3,GCK,ADAM28,GPD2,B4GALNT4,HPS5,ARHGAP19,KCNC2,KCND1,STXBP5,MYL3,P2RY13,ENPP2,PLP1,SMIM7,STRN3,FAT3,NKAIN1,RAD51D,ZDHHC4,TMEM100,STK32B,NFASC,AGTPBP1,TRPM2,TST,ZFAND5" Coexpression M7296 Genes down-regulated in T reg cells: 2h versus 24h medium treatment. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AP2A2,ANXA7,CCDC181,SYNJ1,CALB1,ZNF445,KMT2C,CLTC,FBXO7,LETMD1,OSBPL3,PDE4DIP,HDAC4,DGKG,RUSC2,GUCD1,RABGAP1L,SLC12A6,ATL1,MBNL2,ASB3,KIAA1109,ARFGAP2,STARD3,GNAS,ZNF496,GUCY1A1,HPS5,VWA5A,NCOA7,ZFYVE27,SRSF12,P2RY13,PBX1,ANLN,PDZRN4,CNTLN,PRR5L,SLC6A9,ABTB1,TTC17,ZSWIM8,CLUAP1,LRTM2" Coexpression M9216 Genes up-regulated in CD8 T cells treated by inteferon alpha: wildtype versus STAT4 [GeneID=6775] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,ADD1,ESYT2,ADRB2,TBC1D14,PHYHD1,CDC14B,NUMB,N4BP2L1,GPR146,CFLAR,FOXK1,KYAT1,CACNA2D2,ANKRD44,RGS6,PDE4DIP,ERC2,WDR20,RASGRP1,CALCRL,LRRC23,EFS,TRMO,CELF1,SARAF,TRAF3IP2,GALR1,ACSS1,BACH2,IL6ST,DIPK1A,MBP,MITF,SETD4,ZNF655,RASGRF2,RASA3,SGK1,PEX26,TNIK,TGFBR3,NACC2,LRRC24" Coexpression M309 Genes down-regulated in primary bronchial epithelial cells stimulated with: IL22 [GeneID=50616] versus IL17A and IL22 [GeneID=3605;50616]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "METAP1D,RNF157,MTA3,ZNF608,OSBPL1A,PHF12,BTRC,CARS,CD38,CLCN3,ARHGEF10,IPCEF1,PPP1R16B,CTNND2,DLG4,SLC43A2,EZH1,TBC1D16,EVL,C2orf88,SORBS1,OGA,FYN,TRAF3IP2,PTGDR2,HSF2,LRRC75A,ITPKB,MEF2C,PDE4B,PHKG1,SLC26A11,KIAA0895L,SLC14A1,TET1,ZFP1,SMARCA4,CDK19,FCHO1,TBX15,CYB561A3,ATP13A2,TP53BP1,SEZ6L" Coexpression M6060 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus TGFB1 [GeneID=7040] and IL-12 (6h). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "CLK4,ARID1A,ALCAM,MADD,CDK13,EIF4G3,STX16,ARHGEF7,RAB29,CAPN3,ARMC8,NCOR1,HDAC4,KIAA0586,ZBTB24,TRAPPC9,HIPK3,PLXNC1,LPAR6,SRRM1,FDFT1,ATP5PD,VTI1B,GALC,CBX1,PRUNE2,GRM8,LIG4,MDM4,NAP1L1,NFYA,OLA1,PLCB2,PID1,DPF2,TRA2B,WDR47,CLUAP1,SEMA4A,PIK3R5,EIF4ENIF1,VAV1,ACTR3B,FXR1" Coexpression M8775 Genes up-regulated in dendritic cells: wildtype versus NLRP10 [GeneID=338322] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADAR,MTA3,PPFIA4,ARNTL,SYNJ1,ENTPD6,CSF1,KIAA0040,RASA4,STARD3NL,ETV1,TAOK3,FCGR3A,GCNT2,GPT2,GRIK2,INPP1,DIPK1A,PIK3AP1,SESN3,NAP1L2,SMOX,C19orf57,ARID4A,MCMBP,PLPPR3,RASA3,FNDC3A,URGCP,INTS9,RGL1,TAL1,TCF4,CDH22,TIAM1,RGMB,WRN,NDRG4,ZNF213,CAB39L,PARP11,DOCK8,CERS6,NHSL1" Coexpression M7451 Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: IL6 [GeneID=3569] versus TGF beta and IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "EIF4G3,CNN3,TOX,ARMCX2,DCTN1,EFNA3,EGR3,PLEKHA1,CD320,FOXG1,PNMA2,DENND2A,RAPGEF6,KIRREL3,GPM6B,GPR34,GYG1,IRF8,MSL1,PAXBP1,SESN3,SSH1,TMIE,PLCB2,RC3H2,RETREG2,PACSIN1,RASGRF2,BSDC1,RFX5,CCDC112,KANSL3,ZKSCAN3,RCOR3,SON,CAMTA2,MAPK8IP3,VWA3A,GZF1,DAAM2,ZNF711,PARP6,HPS4,PARP11" Coexpression M3025 Genes down-regulated in comparison of effector CD8 T cells at the peak expansion phase (day8) versus those at contraction (day 15) after LCMV-Armstrong infection. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "DGCR6,ADCY6,CASK,ARRB1,BCL2L2,CAMK2B,CDK11B,LY86,ABCG1,RABGAP1L,NR1D2,ABCC5,E2F5,FEM1B,PLEKHA1,RABEPK,ERCC2,RPS6KC1,EVL,NSG2,GATM,GLUL,IL6R,MAT2A,CNOT4,SLC11A2,PCSK5,PDE4B,PKD1,POLG,POU6F1,ZYG11B,RGS10,SELL,ZNF821,GALNT10,SCG5,TCF4,KIAA0930,TCF7,TJP1,CADM1,VLDLR,ZSCAN26" Coexpression M9850 Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "MTUS1,SNX32,ABCD2,MRTFA,DGKZ,PDXK,ADAM15,RCBTB2,KMT2C,SLC25A27,IFFO1,ABCG1,ARHGEF4,RASSF2,KIAA0586,PLXNC1,LPAR6,EPS8,PCYOX1,FOXO3,TOX3,ZBTB45,IRF8,LAMP2,INSYN2,MBP,SETD4,MINDY2,PTPA,DIRAS2,ELP2,SGK1,ATF7IP,MYCBP2,FAM168A,VAMP1,SLC37A2,ATMIN,KIAA0930,TCF12,SZT2,CRTC1,CDK20,PORCN" Coexpression M6255 Genes down-regulated in T cells: CD4 [GeneID=920] versus CD8. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "VAT1L,BRINP2,TTC9B,ADGRB3,CA4,CALB1,CALB2,AKAP5,LYPD1,NTM,WDR20,FIS1,USH1C,FAM135B,EDN3,EPHA5,CACNG3,MED12L,PTPN5,HPS5,SMAP1,KIF5A,KIT,LAMA2,MEIS2,GON4L,WDR25,KHDRBS2,SCN2B,CCDC92,YPEL4,PDZRN3,NPAS3,ADGRL3,AKNA,TMEM9,TJP1,DDHD1,TMOD1,SYNPO2,DCBLD1,FLRT1,PLPPR5,PCDH15" Coexpression M5426 Genes up-regulated in comparison of mast cells versus dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "BEGAIN,TRMT9B,RGS9,BCL2L2,DST,BTK,ARHGEF6,MAGED1,ABI3BP,OSBPL3,TOX,NCALD,LINC01278,NBEA,FYN,BRD8,GRB10,ITIH2,VWA5A,MAOB,MEIS2,PCDH8,PMP22,PSAT1,PEX2,RFX5,NCBP3,FRMPD1,ZCCHC24,KIF21B,HECW1,TSPYL2,COLGALT2,STX1A,ANKRD28,TAL1,PCDHGA3,HEY1,TMOD1,TRIO,ZMYND8,CA14,ZNF711,ZNF23" Coexpression M8648 Genes down-regulated in bone marrow-derived macrophages: control versus stimulated with LPS. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABCD2,PDE8B,KYAT1,RCBTB2,B4GALT6,CNOT8,HDAC9,FAM107B,DOCK2,EEF1A2,RTN3,PCYOX1,SEMA4D,OGA,ZMAT1,STAG2,ACSS1,GPR162,MSL3,CACFD1,NR3C1,GSN,HMGCL,L1CAM,CAMK2N2,PIK3AP1,OPHN1,FTO,PRIMPOL,RETREG2,RGS10,CLIP1,RASA3,ITSN1,KIF21B,BEX1,TMEM150C,ARHGAP9,SLC44A1,SYNPO2,TST,DNAJC12,NAV2,MPPE1" Coexpression M4545 Genes up-regulated in comparison of thymic progenitors versus DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "APP,ARRB1,BTK,CD86,CD81,LY86,ZNF521,CSF1R,SOCS5,MYADM,SIRPA,ARRDC4,EBI3,PCYOX1,JKAMP,SPECC1,STAU2,FYN,NEK6,IQGAP2,ATP8A2,GCNT2,GGT5,MAP4K5,HLF,ICA1,DOCK7,KCNH2,LMO2,MEF2C,MITF,PPP3CA,PTK2,PTPRE,RGS10,FAM102A,FHOD3,GKAP1,SAMSN1,TAL1,TJP1,TTC3,TTPA,ZBTB14" Coexpression M3198 Genes up-regulated in comparison of naive B cell versus pre-germinal tonsil B cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ARRB2,MARCH3,PTCH2,CDK5R1,RAB29,DDR1,EPS15L1,FBXO7,PITPNM3,PUM1,DNM2,FEM1B,RBM12,USPL1,PTK2B,FCGR1A,FGF1,TRMO,SARAF,RUNDC3A,SYNPO,HMGCR,MAN2A2,MBP,NELL2,NME4,FXYD1,ING3,PPP3CA,PRODH,TUG1,RGS4,ZNF532,ZNF331,SLC6A1,SAMSN1,DDHD2,PDLIM2,WBP2,TTTY15,ZNF154,TUBA1A,WIPF2,MPPE1" Coexpression M7414 Genes up-regulated in neuron cell line treated with interferon alpha for 6h: immature versus mature. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADAR,TNRC6C,ZFYVE28,MARCH3,NCOA1,IL33,ENTPD6,RIPOR2,SNPH,RIMS3,SNX29,EEF1A2,PLEKHO1,LRRC17,ERBB2,NRN1,FOXO3,EVL,AFF2,DACH2,HIGD1B,GHR,TOX2,MSL1,KIFC3,SMAD9,LRP1B,PCSK5,PFKFB4,PACSIN1,PRKCZ,TTLL7,PRR5L,SOX8,RTN1,SPHKAP,TTC17,DBNDD2,SYNE2,SYT1,KCNE5,KLC2,WIPF2,AP3B2" Coexpression M7905 Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "NCKAP5,CASKIN1,MARCH3,PROM1,KRIT1,COPB2,SYNPR,JAM2,NRSN1,GAPVD1,E2F5,SNX29,PAN3,EPHA5,SPEG,SCML2,GABRB1,RAPGEF6,GART,GGT5,GPD2,NUDT21,GRM5,HSD17B1,IDH3A,KCNJ11,LYPLAL1,MID1,NAP1L3,SMIM11A,PCDH9,PPM1B,RANBP3L,RAB3A,ZNF493,CLIP1,LRRTM4,DZIP1,SLC1A2,URGCP,IQSEC2,EVI5,ZDHHC20,SLC39A12" Coexpression M6466 Genes up-regulated in CD4 [GeneID=920] T cells versus B1 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "KIDINS220,RASL11B,ST3GAL5,LY86,ZNF385A,CST3,SDC3,MYADM,DCTN1,C8orf34,SEC16A,TUBA1B,OLFM1,FGFR1,TACC2,KDM2B,POLL,GSN,ARHGAP19,ELOVL5,JAK2,MBNL1,DBNL,CCDC80,STK32C,RAB39A,ROGDI,KCTD17,RTN1,SMTN,MBD5,PALLD,EPB41L3,SULF2,STXBP1,FAM168A,AHCYL2,FNDC5,PITPNB,WRN,ATP6V0E2,CIAPIN1,SIGLEC10,FRMD6" Coexpression M3220 Genes up-regulated in comparison of regulatory T cell (Treg) versus conventional T cells activated with lamina propria dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "NDRG2,SORCS2,BCAS1,CLTB,QKI,KIAA0513,ARMCX4,RABGAP1L,DLG3,FIS1,EBI3,NRN1,ADAMTS6,ZDHHC15,TUBB2B,KLRC2,MEST,SAMD14,NUCB2,SSH1,TMEM38A,SMOX,PPM1B,PRKAR1B,PSD,PLEKHB2,RAP1GDS1,BEND5,SLC25A36,ATXN2,TRIM46,SGK1,DOCK10,ZKSCAN3,PBLD,CAMSAP2,PSD3,TEK,SLC44A1,TIAM1,VAV2,PLD4,ST7,NLRP3" Coexpression M8090 Genes up-regulated in myeloid-derived suppressor cells from bone marrow: wildtype versus HDC [GeneID=3067] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ARID1A,ZNF608,TBC1D14,ALCAM,PKP4,TMEM108,DOCK11,BACH1,MAP7,CCNH,NRXN1,SLC4A7,CSNK1G3,SLC12A6,SEMA3D,SRPK3,PAN3,EPB41L2,CDKL3,ATP8A1,MEX3B,FOXO3,C2orf88,ACSS1,GLUL,GSN,MSL1,LMO2,LDLRAD3,TM6SF1,CD200,DDX25,PRKACB,PXK,CEP97,ARID4A,RFX5,RGS10,CHD9,SLC14A1,CEP68,CADM1,SLAIN1,XPO1" Coexpression M9158 Genes up-regulated in CD4 T conv over-expressing LEF1 [GeneID=51176] versus LEF1 and FOX3P [GeneID=51176;50943]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AS3MT,TKTL1,ZNF608,TBC1D14,CC2D2A,ALAD,C6orf89,APLP1,MIER1,JAZF1,CAMK2D,CD38,CD81,LRBA,CDC25B,AKAP7,SLC4A7,ATRNL1,LONRF1,CD99L2,SESN1,KDM2B,STON1,AGFG1,SMAP1,KIF5C,MATK,CD200,ZNF862,PENK,SSH1,PLCL1,PPM1B,SYTL2,FAM120C,RALGDS,MAPK12,CHD9,SLA,AHCYL2,ZNF23,WNK1,SNX14,SPATA13" Coexpression M4458 Genes up-regulated in comparison of monocytes cultured for 0 days versus those cultured for 1 day. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADD3,ALAD,GAS7,ASGR1,BTK,MTMR3,CAST,LY86,CSF3R,IPCEF1,CST3,KIAA0040,CX3CR1,KIAA0513,SIDT2,FAM13A,RASGRP2,TLR7,F5,ATP8A1,FCGR1B,FYB1,PSRC1,PADI2,LMO2,MBNL1,MEF2C,MXI1,P2RY13,NINJ2,NRGN,PIK3CD,PLCB2,MARCH1,RFX5,SATB1,SELL,ST6GAL1,SMARCD3,MYCBP2,RAP1GAP2,LHPP,AGTPBP1,NACC2" Coexpression M6560 Genes down-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone and AM580 [PubChem=77999;2126]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADCY8,ALAD,ZMYM4,CLU,MAGED1,GSDME,DNM1,RCAN1,GOLGA7,FGFR1,BAIAP2,GALC,GAP43,WASHC2A,GPR162,SESN1,GRB10,GSTM5,IGF1,STMN1,LSS,ASPRV1,MAP6,NCAM1,NPY,PAK3,CDK18,PDGFRA,OLA1,CDK14,QRICH1,RGS10,RNH1,EMID1,ITSN1,SLC6A8,SPP1,TAC1,SLC44A1,METTL3,TTC3,LAT2,SPHK2,FRMD6" Coexpression M4442 Genes up-regulated in comparison of naive B cells versus plasma cells from bone marrow and blood. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "PARG,DGKZ,ARHGEF7,DDR1,LRBA,CLCN4,LY86,NIPBL,NSL1,CREM,GPRASP1,EVL,SMC2,TPK1,GABBR1,CHL1,SEPT9,GPM6A,EML4,ARHGAP19,IRF8,ITPKB,CD200,NASP,PIK3CD,STRN3,PKIA,PRKCB,RADX,UBR7,ZNF532,RPL38,SELL,CPEB3,WDR37,SLA,INTS9,KIF21B,PEG10,CDK19,SIN3B,SZT2,FRYL,KAT6A" Coexpression M3107 Genes down-regulated in comparison of naive T cells versus central memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "KIAA1324,CASK,ZFYVE28,ARHGDIA,ARNTL,ATP2A2,CAST,SPAG9,MICAL2,OSBPL3,RABGAP1L,TOM1,TSPAN5,KLHL5,SH3GLB1,GOLGA7,F5,IQGAP2,RAPGEF1,ELOVL5,SMAP1,IFI16,TTYH2,LIMS1,NCOA7,AFDN,MYO5A,FXYD7,OGDH,PFKP,PKM,RGS3,FBXW7,PRR5L,RYR1,ATXN1,GALNT10,ST8SIA1,KIF1B,MPRIP,GSE1,GPRIN3,TGFBR3,CLDND1" Coexpression M5255 Genes down-regulated in comparison of macrophages exposed to T. gondii versus macrophages exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "NDRG2,KCNAB2,GAS7,CDC14B,LDLRAD4,ENTPD6,CHI3L2,CLTA,CLTB,TMEM184B,LY86,CNR1,IFFO1,RASSF2,INTS1,IST1,DOCK2,SNX29,AASS,PTK2B,RAB40B,LILRA2,RASSF8,VSIG4,INPP5B,KCNJ9,PTPA,RELN,NDUFS7,PTAFR,PYGM,PLEKHB2,S100B,NTNG1,SMARCD3,ZNF415,ERC1,IQSEC2,RGL1,WDR7,TPD52L2,UGT8,ZNF45,SPHK2" Coexpression M6961 Genes down-regulated in plasmacytoid dendritic cells in response to CpG oligodeoxynucleotide 1826: 1h versus 4h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "API5,CDK13,DYNLL1,HCN2,CDC25B,MFSD4A,IPCEF1,KCTD8,DLX1,DYRK1A,SEMA3D,RASA4,PAN3,RCSD1,TLR7,BAIAP2,FOXM1,TMEM107,GALR1,NEK6,GRIA2,CIT,STMN1,TM6SF1,POC1B,MN1,MSRA,N6AMT1,NODAL,ING3,KLHDC8A,FHOD3,ANKRD6,CXXC4,ZSCAN29,TCF4,AKNA,GPR161,PIK3R5,TRIO,PDSS1,LRP8,MSRB3,FRMD6" Coexpression M6393 Genes down-regulated in B lymphocytes: germinal center versus memory. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "CLK4,AMPD3,PPFIA3,BSN,CD81,KCNAB3,TPP1,ZFP28,ACOT8,TSPAN5,HIPK3,PHF20L1,MRNIP,AMZ2,TBC1D16,ATP6V1H,GLUL,ADGRA3,COQ10A,ZFYVE27,MEST,HNRNPM,ZNF827,MINDY2,PRPH,PPP2R3C,RAD52,RGS10,RIC8B,TMLHE,NCBP3,ZNF821,CHD9,RUFY2,SMARCE1,RCOR3,CDK19,ANKRD12,PSD3,TMEM121,TK2,MEIS3,PARP6,CAB39L" Coexpression M4849 Genes down-regulated in comparison of CD8 T cells versus monocyte macrophages. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "RALGAPA1,OSBPL8,MRTFA,AMPD2,API5,ARRB1,RNF182,ARHGEF25,CDK11B,CLTA,MAML1,SPOCK2,DMD,DMPK,SLC25A18,ANKRD46,OPTN,YAF2,CACNG2,TPPP3,GRB10,PARD3B,KCNMA1,LDLRAD3,MYBPC1,NFYA,NRDC,PALM,ETFRF1,UEVLD,MRAS,HSPA4L,FHOD3,CPEB4,TACC1,MCF2L,AGTPBP1,CBX5,WBP2,ZNF384,TRPM2,SGK3,GORASP1,NETO2" Coexpression M3419 Genes up-regulated in comparison of regulatory T cell (Treg) from IL2RB [GeneID=3560] defficient mice versus effector T cells from IL2RB [GeneID=3560] defficient mice. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABR,ADD3,ESYT2,BIN1,PKP4,APC,SHTN1,ATP1B3,CAST,FMNL3,CBFA2T2,ZMYM4,DYRK1A,LPAR6,FYN,BRD8,SPIN1,RFFL,MAT2A,MBNL1,PDE2A,ABCB1,PIK3C2A,PKD1,ANKRD16,MED1,PRKCZ,SNRK,ANKHD1,ZNF493,OXR1,ZYG11B,EXD2,SBF1,CHD9,ZC3H13,MAPK8IP3,SULF2,PUM2,DHX33,PARP6,PPP1R3F,TTC7A,ADAMTS10" Coexpression M4567 Genes down-regulated in adult DN2 thymocytes versus adult DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,ARNTL,EIF4G3,N4BP2L1,BID,CCNH,CCPG1,CS,CNTNAP2,YTHDC1,EDNRA,GPHN,NSG2,RAPGEF6,ARPP21,NCKAP1,GFRA1,NR3C1,MARK3,MBP,NEFH,NRDC,PDPK1,CAMKV,PKD1,ZNF426,SH3KBP1,PRKCB,SNRK,RAD17,RGS10,ARHGEF10L,RYR1,SATB1,DZIP1,CPEB4,KDM3A,POPDC3,DICER1,ZMAT3,IL34,EIF4ENIF1,SLAIN1,PLD4" Coexpression M3048 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AMPD3,OGT,DGKD,API5,NAE1,TRIM41,C1orf52,CHM,CLCN3,APPL1,ZFYVE16,MATR3,TOMM20,HIPK3,RASGRP1,RBM12,GPHN,SRRM1,CAMKK2,MPP6,ZMYND11,BACH2,HNRNPK,OPA1,MINDY2,PTCH1,TTC13,RASGRF2,REV3L,SLC25A36,SATB1,ST6GAL1,ST8SIA1,NUBPL,ABTB1,TNIK,POGZ,ACTR6,BHLHB9,ZNF384,TUBB2A,USP1,BCL2L13,MFF" Coexpression M6352 Genes up-regulated in gamma delta T cells stimulated by LPS: Vd1 versus Vd2. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADCY6,PKP4,DGKZ,BCL7A,ASIC3,QKI,WHRN,MAGED1,TOX,SPOCK2,ARMCX2,OPTN,KCNMB2,EZH1,RACK1,FGF13,ATP13A4,FYB1,B4GALNT1,ERAP1,GLRB,FERMT2,EML4,RAPGEF1,JAK2,PCBP3,ENPP2,MBOAT7,ANKHD1,ZMAT4,RGS12,RIT2,ZNF365,CDK19,SRPK2,SYT11,ANKRD12,ZEB1,WASHC4,DICER1,TP53BP1,ZMYND8,TTC3,FXR1" Coexpression M4323 Genes up-regulated in comparison of TconvLP versus Homeo Foxp3- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ANXA7,CDK10,DOCK11,CD38,SRSF11,TAOK2,CHD1L,OSBPL3,IPCEF1,DCAF8,ABCC5,FDFT1,ANKFY1,ST6GALNAC3,OGA,GABBR1,ERAP1,TUBGCP4,MALT1,BRD8,ADAMTS6,INPP1,INPP5B,KLC1,ARHGAP12,MAT2A,LRP1B,P2RX7,TMIE,PKD1,PPP3CB,EML5,PTPRE,KCTD17,SEC61A2,RIMKLA,MYCBP2,AP4E1,ERCC6L2,RUNDC3B,PARP6,TTC7A,ZDHHC20,KLHDC1" Coexpression M8032 "Genes down-regulated in macrophages (12h): IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999] versus rosiglitazone [PubChem=77999]." MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,ADD3,MTUS1,CDK13,STX16,ST3GAL5,MYOM2,LRBA,CHI3L2,RAB33A,ZFYVE16,ZBTB24,EGR3,VPS13B,EZH1,SH3YL1,ATP8A1,SEC24B,SEMA4D,USP16,STAG2,CAB39,ZNF274,IL6ST,ITPKB,KLRC3,MAN2A2,MARK3,NELL2,PDE3B,PIK3C2A,ING3,MED1,PPM1B,PPP2R5E,ROBO1,PCMTD2,GALNT10,RAB3GAP1,ELMO2,COA1,JMJD6,PJA1,TIAM1" Coexpression M5231 Genes up-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SYN3,CDC7,PKP4,LRBA,SLC4A7,RCHY1,AHCTF1,GAPVD1,BRINP1,ELMO1,KIAA0753,CEP170,EIF4G2,SRRM1,EFEMP1,FCGR3A,FGF1,ATP5PD,GABRA2,MYOZ2,PRRC2B,GRIN1,PSIP1,HNMT,LMO2,MBNL1,NHLH1,PGAM2,ABCB1,PRODH,PTPRN2,RNASE1,PUF60,ITSN1,FAM214B,DOK5,NFASC,TACR1,FBXW11,WSCD1,DNAH7,RUSC1,USP1,KAT6A" Coexpression M3589 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with IL12 . MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SLC25A25,BRAP,ADRB2,MAP4K3,APP,SEC11C,FOXK1,HIP1R,MAP7,ARHGEF25,CCKBR,USP2,AKAP7,ABCG1,IP6K1,USP3,ACOT8,EEF1A2,SUGP2,RASGRP2,TLR7,USP21,GABBR1,INPP5K,CNTRL,RAPGEF4,COQ10A,INSM1,KCNH2,MATK,SYT9,MX1,PDE4B,PKD1,SPATA6,RETREG2,PLEKHB2,BSDC1,ZYG11B,RFX2,SOX11,ST5,MAPK8IP3,EXOC7" Coexpression M3940 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "APAF1,PDXK,ARHGAP5,BARD1,BID,CBR1,TJP2,RCHY1,IGDCC3,ABCG1,PNPLA8,OLIG2,PIPOX,TUBA1B,RACK1,OLFM1,FGF13,GAB1,PSRC1,PLPP7,PSIP1,WIF1,HMGB1,KIF2A,STMN1,MIA2,DBNL,MXI1,NCF2,PCDH8,UHRF1BP1,RAP1GAP,TMLHE,RPL38,HES6,SGK1,FNBP1,KIF1B,SRPK2,CEP68,EXOC7,FRYL,DNAJC12,DPYSL5" Coexpression M4338 Genes down-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "GALNT13,RNF157,ALCAM,ARNTL,SEC11C,BCHE,NIPA1,BAIAP3,MAGED1,CSF1,OSBPL3,PNPLA8,CYBB,ARMCX4,TMEM130,DMD,ARRDC4,HSPA12B,TMEM175,GAA,NCKAP1,DCLK2,FRMD5,KLF12,KCNK3,KIF5C,LAMP2,VWA5A,CHIC1,NUCB2,MDGA2,STK32A,CLIP1,IL17RB,PEAR1,CHD9,ANKRD6,ATP10B,WDR7,ZNF142,DHX33,WNK1,EVI5,NAV2" Coexpression M9844 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "TMCC3,ALCAM,BRSK2,PPT2,SLC25A27,NECTIN3,MAMLD1,RASGRP1,PLXNC1,LINC00599,F8,SEC23B,STAU2,TUBGCP4,TMEM121B,BVES,SLC2A6,INPP5B,JAK2,KCNN3,MX1,NF1,DDR2,PRPH,TMEM104,RFX5,UEVLD,RTKN,SEMA6D,CPEB3,SHC4,KBTBD4,TSNAXIP1,UNC5B,ATP10B,SYN1,TBX15,PCDHB6,CBX5,CFAP52,NDRG4,FSTL5,NAV2,GJC2" Coexpression M7305 Genes down-regulated in T conv cells (24h): medium versus TNF [GeneID=7124]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "EMILIN3,PLEKHH1,ADORA3,APC,APLP1,CFAP410,DDR1,CERS5,CHM,EPS15L1,CLCN4,FAM189A2,FAM171B,CHD5,RAB39B,ACOT8,ABI1,BSCL2,SH3YL1,B3GAT1,PHYHIPL,LNX1,GRK4,CLASRP,NXPH3,SHISAL1,PDE4B,CYTL1,SLC36A4,POU6F1,SLC26A11,BCAS3,PID1,USP47,PLEKHB2,ATG16L1,C12orf49,DRAXIN,FBXO11,ERC1,DNMBP,TF,RGMB,ZFAND5" Coexpression M6426 Genes up-regulated in CD4 [GeneID=920] T cells versus NKT cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ARID1A,NDRG3,KRIT1,ARMC8,EDRF1,DOCK4,HDAC4,HIPK3,EVL,C2orf88,B4GALNT1,SEPT9,INPP5K,GPD1,CNTRL,GRM1,IL6R,INSM1,KHK,ERICH3,MYO9A,P2RY13,PDE2A,ARID4A,RGS12,PCMTD2,AMBRA1,CCDC88A,ELMO2,PDZD2,KIF21B,CDK19,CAMTA2,FGD4,PDLIM2,ZEB1,SZT2,SYNE1,MTMR14,NR2C2,RICTOR,LRP8,TMEM178A,SENP7" Coexpression M6638 Genes up-regulated in bone marrow-derived macrophages at 45 min stimulation by LPS: wildtype versus IL6 [GeneID=3469] knockout. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "PLA2G6,DGKZ,ASPA,AHCTF1,IST1,FAM107B,SNX29,ING4,PCOLCE2,EFEMP1,TMEM164,NELFCD,SPECC1,STAG2,GALNT15,KDM2B,GSTT2,DOCK7,IBA57,CREG2,PAXBP1,KITLG,MYO5A,DDR2,OPHN1,PDE3B,GDPD1,QRICH1,REV3L,ERI2,PCMTD2,PALLD,SCN3B,SON,UHRF1BP1L,CLASP2,POGZ,EPB41L3,SLC37A2,ALG1,SIK3,TGFBR3,HEY1,ZNF24" Coexpression M3722 Genes down-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with poly(I:C) (TLR3 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "TTYH1,ACTN1,NDRG2,PKP4,HCN2,NAE1,CBLN1,CHGA,CNN3,HINFP,VCAN,ECE2,BLOC1S6,GUCD1,ARNT2,ABI1,DYRK1A,EGFR,CACNG3,GAP43,TUBA8,STARD3,PACRG,SMAD9,PIK3AP1,DDR2,PC,DUSP26,POU3F4,OCIAD1,PTPRO,TMEM206,MCMBP,SLC2A5,PALLD,TAB2,SSTR1,PHLDB1,STXBP1,SYNE2,WASHC4,TEK,PITPNB,HRASLS" Coexpression M9925 Genes down-regulated in B lymphocytes: untreated versus anti-IgM for 24h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ARID1A,FZD9,ATP1B3,BACH1,CCPG1,FAM171B,APPL1,RIPOR2,CENPL,LIN54,ARMCX4,PARD6A,KBTBD11,DYRK1A,MBNL2,RASGRP2,SUCO,MEX3B,PCYOX1,DOT1L,GLUL,MFSD2A,IRF8,MSL1,KIT,STMN1,AFF1,SFR1,ZNF655,RASGEF1B,MSANTD2,ZYG11B,KLHL11,MCMBP,FNIP1,SLC12A4,CPEB4,PALLD,ZSWIM8,TEX2,KLHL7,MTMR14,TP53BP2,UBE2H" Coexpression M9677 Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 20h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "FZD9,APBB2,APOC1,APOC2,DDX3Y,CACNA2D1,B4GALT6,CHRNB2,LY86,CNN3,CSF1,HEPH,FGFR1,FHL1,SGIP1,FOLR2,SARAF,ADAM28,ZNF638,FERMT2,GPR37,KLF12,AGFG1,IRF8,IGFBP1,KCNH1,MARK1,MDFI,MX1,MYH7,DDR2,OLR1,PCSK2,PDE1A,CDK14,SERPINE2,EPB41L4B,ATXN2,KLHL7,TAF9,WRN,SLC30A4,FIP1L1,FRMD6" Coexpression M9498 Genes down-regulated in CD8 T cells: naïve versus effectors at day 8 after acute infection with LCMV-Armstrong. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AP2A2,ANK1,FGD2,CNIH2,KRIT1,GPR37L1,MS4A7,EDRF1,AIF1L,ZC3H11A,MED12,SLC29A4,EIF5,MFSD10,FGR,TMEM175,GPR153,IQGAP2,DCLK2,RAPGEF4,HSD17B1,SMAP1,IL11RA,ZFYVE27,PDE2A,PDE1B,SPATA6,RIPOR1,RAB3A,RALGDS,ATG16L1,TRIM68,EMID1,KDM4C,TCF12,SIK3,ATP13A2,TF,ZNF106,NACC2,SGK3,SLAIN1,RNF103,SNX14" Coexpression M7177 Genes down-regulated in B lymphocytes from cord blood: naïve versus transitional CR2 [GeneID=1380]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABHD6,SNX30,FGD2,APAF1,CADM3,ST3GAL5,SPAG9,TJP2,QKI,ARHGEF6,DSCAM,RCAN1,GOLGA7,STARD3NL,SRRM1,FCGR3A,SPECC1,GATM,MALT1,KDM2B,RAPGEF1,SLC2A6,RBPJ,DIPK1A,ITGAM,GPR155,ABCB1,EPN1,PRKCB,PTPRE,KCNIP3,FNIP1,SULF2,SYPL1,TEX15,SLC44A1,CBX5,TMPO,TNS1,TPM2,EIF4ENIF1,AMZ1,EVI5,NELFE" Coexpression M4483 Genes up-regulated in comparison of naive B cells versus unstimulated dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "CDC7,ARHGAP5,MARCH3,BCL7A,DDR1,CD38,LRBA,LARGE1,CLCN4,CNR1,GPRASP1,RIPOR2,TIAM2,SNX29,CORO2B,TESK2,GABBR1,GPM6A,BACH2,MEF2C,MEST,MID1,CD200,OGG1,RETREG1,POU6F1,MINDY2,SIDT1,MTMR10,RADX,ZNF532,TMEM156,SELL,ZNF821,CNKSR2,IDI2-AS1,PEG10,TSPYL2,ACSL6,ZEB1,SZT2,PCDHGA10,ZNF154,ITM2C" Coexpression M5167 Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (50 worms/well). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,APLP1,ADGRB2,CAMK2B,KRIT1,CLTA,CLTB,CNR1,MYRIP,RNF14,DZIP3,ZNF804A,COPS7A,SACS,F3,CACNG3,NCKAP1,HPS5,IGF1,INPP5B,ITPKB,KHK,MX1,CNOT4,OGDH,PCMT1,PDCD2,MBOAT7,PYGM,RFX2,CLIP1,FAM102A,BTBD3,SLC11A1,SOX11,SP2,IQSEC2,COLGALT2,NCDN,ARC,TMPO,TNR,RNF103,KCNAB1" Coexpression M5463 Genes up-regulated in comparison of dendritic cells (DC) versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ASPHD1,ABHD6,APP,ARRB1,CD86,LRRFIP1,TPP1,CLTC,MICAL2,IPCEF1,CTH,DAPK1,RCAN1,E2F6,ARMCX1,SEC23B,ATP6V1H,GBX2,GPD1,LILRA2,EML4,GSTT2,ACOT7,MAOB,TM6SF1,MITF,PDE4A,PFKP,SMIM7,PILRA,ARHGEF10L,RXRA,MRAS,PALLD,TMCC1,BEX1,ZBTB43,ROBO3,TAL1,TGFBR3,TK2,TNS1,TST,NLRP3" Coexpression M9745 Genes up-regulated in follicular helper CD4 [GeneID=920] SMARTA T cells (Tfh): effector during acute infection of LCMV versus memory. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABAT,ADAR,TXNDC16,ZNF687,PHYHD1,ATP2B1,ATP6V0A1,BACH1,ST3GAL5,IL33,SPAG9,CD86,UBE2L6,CHGA,TMEM184B,RBM39,RNF14,OSBPL3,SDC3,ELMSAN1,GUCD1,EGR3,TLR7,RBPJ,IL6R,TUBB2B,KTN1,PIK3AP1,PDE1B,RETREG1,GPSM2,PMP22,POU6F1,NKAIN4,SIRT2,SPP1,SRPK2,SAMSN1,TCF12,ICAM5,TBC1D15,LAT2,ZFAND5,PMEPA1" Coexpression M9540 Genes up-regulated in bone marrow-derived mast cells treated with IL3 [GeneID=3562]: control versus IL33 [GeneID=90865]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABHD6,OGT,PDXK,ALDH4A1,SCARB1,REPS2,LRRFIP1,CLTC,QKI,LY86,IFFO1,NCOR2,TBC1D5,SRGAP3,FIS1,EPB41L2,RTN3,FAM198B,ANKFY1,STAU2,CAB39,GATM,GSN,NCKAP1L,MAT2A,MXI1,NACA,OLR1,PCSK5,PIK3CD,PIK3R1,PILRA,PPP3CA,QDPR,PCMTD2,RPS6KA2,DGLUCY,ANKRD6,LMBRD1,GSE1,KLHL7,TACC1,VAV1,MICAL1" Coexpression M9486 Genes down-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 8. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACADM,ADD3,SCAPER,LURAP1,FMNL3,DIS3L,KMT2C,NGEF,LETMD1,CSNK1E,ARMCX4,ZBTB24,WDR20,CPEB2,GNE,DYRK1A,EBF1,EYA1,PRMT5,SYNCRIP,EML4,CECR2,ZHX1,C5orf24,TUBB2B,MBNL1,FITM2,TTC13,RAD17,OXR1,PCMTD2,FBXW7,MCMBP,SMPD3,ZNF821,SHMT2,NXT2,SLC44A1,UCHL1,SLC30A4,ZDHHC20,NETO2,RNF146,GAN" Coexpression M7502 Genes down-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADAR,TMCC3,OSBPL8,CDC14B,TMEM263,NCOA1,CCPG1,RIPOR2,ARMCX2,TMCC2,SLC12A6,KMT5B,F5,CHST15,MED12L,KHDRBS3,GLYR1,NCKAP1L,HNRNPK,STMN1,MEIS1,SESN3,NME4,PBX1,SERPINE2,CNTLN,RNASEL,CCDC25,CHD9,ANKRD6,ATF7IP,CEP68,PLCB1,SMG6,DMXL2,TNS1,TP53BP2,TRIO,CSDE1,PARP11,AMN1,DOCK8,KLHDC1,RNF146" Coexpression M4316 Genes up-regulated in comparison of TregLP versus DEC-Pept Convert (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "NCKAP5,SPARCL1,ATP6V0A1,RCBTB2,CLCN4,TJP2,ARMC8,OSBPL3,IPCEF1,MYADM,BLOC1S6,OPTN,EGR3,SLC43A2,SMC2,DKK3,FAM120B,GALC,RUNDC3A,KIAA1958,B4GALNT4,PADI2,HSD17B1,ICA1,GPR155,PLCL1,SYTL2,RAD17,PCMTD2,RIMKLA,IL17RB,SEC14L1,CHD9,ANKRD6,SLC15A2,RCOR3,C18orf54,CDK20,TMEM237,ZNF189,GDPD5,LMAN2L,NAV2,SSPN" Coexpression M6952 Genes down-regulated in plasmacytoid dendritic cells (1h): CpG oligodeoxynucleotide 1826 versus influenza virus infection. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SLC25A25,AP2A2,AP1B1,AMPD3,SLC4A4,B3GALT2,C1QC,HAP1,LDB2,C1orf52,CHRNB2,ZNF385A,CYBB,GUCD1,ERBB4,TLR7,FCGRT,MED12L,AFF2,COQ5,NEURL4,NEK6,MTHFD2,GRIK5,GSN,HMGCL,JAK2,KIF5C,ABCB1,SNX10,C11orf49,SPATA6,TNPO2,SLC12A2,MAPKBP1,SOX10,PEG10,LHPP,SSTR2,MLST8,ZFP90,NPL,VSNL1,PLD4" Coexpression M9501 Genes down-regulated in CD8 T cells: naïve versus effectors at day 15 after acute infection with LCMV-Armstrong. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "TMCC3,BRAP,CDK10,HIP1R,CPNE6,QKI,AKAP7,RCHY1,CRY2,SUSD5,PUM1,POM121,DMD,MED12,PHF20L1,RCSD1,EZH1,AGAP3,TRMO,SARAF,INPP5K,KIT,LDLRAD3,PDE2A,RALGDS,BSDC1,EXD2,MAPK12,CHD9,SLC20A2,ZSWIM8,KDM4C,ZBTB43,ITPRID2,KIAA1107,ATP13A2,TNFRSF1B,WBP2,RFTN2,TFIP11,RNF103,MPPE1,AMN1,JMJD1C" Coexpression M7156 Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 2h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "RNF157,TXNDC16,ALCAM,BCAR3,FGD2,CAMK2D,FMNL3,STOML1,QKI,SLC4A7,CNRIP1,PPP1R16B,USP6NL,HDAC9,ARHGAP24,PLEKHM1,EGR3,DENND4A,FGR,EFCAB2,HVCN1,DCLK2,RAPGEF1,SLC2A6,IRAK3,TUBB2B,KTN1,NUCB2,PFKFB4,RASGEF1B,PRKCB,RFX5,RNH1,FOXRED2,SH3BP2,PPM1E,MYO18A,CHD9,ST6GAL1,MPRIP,ATP13A2,TLR4,C9orf85,ACTR3B" Coexpression M9742 Genes up-regulated in Th1 CD4 [GeneID=920] SMARTA T cells: effector during acute infection of LCMV versus memory. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "TXNDC16,ALCAM,DGKD,ATP6V0A1,IL33,SPAG9,USP2,CD86,SEPT7,RCHY1,OSBPL3,ELMSAN1,SACS,DMTF1,EGR3,SLC9B2,SEMA4D,GAA,MALT1,GNG4,RBPJ,IL6ST,TUBB2B,ITGAV,NRGN,PDE2A,PDE1B,PFKP,RETREG1,PMP22,RPS6KA2,SARS,FNBP1,SPP1,BEX1,SRPK2,ITPRID2,C18orf54,TPD52,TUBB2A,WIPF1,LAT2,AMZ1,SLC38A1" Coexpression M5191 Genes down-regulated in comparison of dendritic cells (DC) exposed to M. tuberculosis versus macrophages exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADD3,ARHGAP5,ENTPD6,TPP1,LY86,HOMER3,ABCG1,PLCH2,VCAN,SDC3,TCAF1,DLG2,DTNB,PHC2,EFNB3,ENO2,CHST15,FOXO3,SEMA4D,FYN,GALC,SEPT9,ADAM28,PRRC2B,LILRA2,IRAK3,PADI2,VSIG4,KTN1,MSR1,PTOV1,NACA,NME4,PC,RPS6KA2,SCG5,IQSEC2,SYPL1,TBL1X,KIAA0930,PUM2,ZMYND8,SPHK2,UPF3A" Coexpression M8390 Genes up-regulated in spleen dendritic cells: CD8- versus CD8+. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ANK1,APBB1,DDO,LGR5,PDXK,BRSK2,LY86,PPP1R16B,DOCK4,IP6K1,SEMA3D,EML1,SIRPB1,FOXF2,GAB1,DISC1,GBX2,RAPGEF4,GUCY1A1,KLC1,LSS,NCAM2,NEUROD2,OPCML,PPARA,RELN,PTPRZ1,RYR1,FRMPD1,SLC2A5,SLC6A1,SLC22A4,MAPKBP1,MYO16,ARHGAP26,MCF2L2,NPAS3,DDN,GSE1,TAC1,SATB2,NR2E1,TNR,VIPR2" Coexpression M5617 "Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB1 [GeneID=7040] and IL6 [GeneID=3569] versus those treated with TGFB1 [GeneID=7040], IL6 [GeneID=3569] and IL23A [GeneID=51561]." MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SEMA7A,WASF1,DDR1,MTMR7,CD86,CD38,ARHGEF2,CACNA2D2,DNAJB5,AHCTF1,SMARCAL1,OSBPL3,GAPVD1,INTS1,ARMCX4,BLOC1S6,POM121,TNK2,STX2,FKTN,TACC2,ATP6V1H,GCNT2,GPD2,GSN,TOX2,NCKAP1L,HNMT,MSL1,PDPK1,PIK3R1,ZNF655,MAPK9,PTCH1,SGK1,FNDC3A,KANSL3,SPART,STX1A,FBXW11,ZEB1,TIAM1,UBE2H,RSPRY1" Coexpression M7889 "Genes up-regulated in macrophages (12h): control versus IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]." MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "LRFN2,BCL2L2,PROM1,SYT6,CHRM4,JAM2,RCHY1,KIF26A,DCT,B3GAT3,SV2A,TMCC2,CACNG7,EGR3,CEND1,C2orf88,RASL10A,MALT1,TNRC6A,HLF,OPALIN,HSPA1L,ITPKB,NCOA7,LYPLAL1,HS6ST3,PCDH9,EXOSC10,PRKAB2,LAMA1,RAB3A,SCN3A,LRRTM4,TRIM46,CPEB3,ZEB1,TNFRSF1B,IL34,ELP5,TRO,FNDC5,NTSR2,LAMP5,ZFAND5" Coexpression M7229 Genes down-regulated in T cells: control (0h) versus IL21 [GeneID=59067] treatment for 6h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADORA3,AP2A2,TBC1D14,SRPX,WASF1,SOCS6,QKI,RASSF2,RHOBTB1,EPS8,TBC1D16,GLUL,IRAK3,VSIG4,USP54,VWA5A,LDLRAD3,MYO7A,PIK3C2A,ZFYVE21,PMP22,RAB5B,PLEKHB2,RALGDS,RADX,C12orf49,GLDN,ITSN1,KIF16B,ABLIM3,SNCA,ERC1,SAMSN1,LARP4,RGL1,TCF12,DAAM2,TNS1,PIK3R5,TPD52L2,SGK3,P2RY12,ZBTB16,SNX27" Coexpression M3236 Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ATP1A2,STX16,ALDH7A1,MTMR3,JAZF1,MAP7,CD86,MYRIP,IPCEF1,SIPA1L1,DCAF4,DCAF8,KIAA0586,PITPNC1,DNAJC6,KIAA0753,DLG3,USP3,LPAR6,ATP8A1,DOT1L,DKK3,TPPP,DIPK1A,VWA5A,IL17D,TM6SF1,DBNL,SESN3,IDNK,NEFH,ABCB1,PTPRE,RGS12,SH3GL3,SLA,TNIK,TACC1,SMG6,DDHD1,TRPS1,SSBP2,MICAL1,FIP1L1" Coexpression M5287 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "RALGAPA1,NDRG3,NDRG2,ADD3,OSBPL8,BIN1,SYNJ2,ARHGEF6,ENTPD4,CRY2,RIPOR2,TOX,PITPNC1,KLHL3,USP3,DOCK2,DYRK1A,MBNL2,RASGRP2,FHL1,TRMO,FYB1,HAPLN2,IL11RA,MSRA,MXI1,LYRM9,NUCB2,PDE4D,PIK3R1,PPP3CA,PRKACB,SNRK,KLHL11,PCMTD2,ZNF331,TTC17,TNIK,NPAS3,RAP1GAP2,KAT6B,TPM2,LMF1,MARCH8" Coexpression M8487 Genes down-regulated in untreated B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "RNF150,SPOP,NUMB,BID,SCARB1,CD38,CD81,CS,CTNND1,COPS7A,G3BP2,EVL,SEPT9,HMGCL,RBPJ,DOCK7,INPP1,KIF2A,KCTD6,PTOV1,SLC11A2,NUCB1,NUCB2,P2RX7,PBX1,PCSK5,PRKAB2,RAB39A,PSMA6,PID1,SEMA6D,SELL,GALNT10,RASA3,MYO18A,FNBP1,ERBIN,DNMBP,TPCN2,SYNE1,DICER1,TIAM1,CLDND1,PIANP" Coexpression M7280 Genes down-regulated in monocytes pre-treated with Ly294002 [PubChem=3973]: control versus HCMV infection. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "NR0B1,ASGR1,DDX3Y,CA4,RUNX1T1,SLC5A11,INA,C1orf52,UBE2L6,CNN3,CRYM,AATK,CTNND2,USP3,EFNA2,MRVI1,TUBB3,FGF1,NKX6-2,GART,GRIN1,GSN,HSPA1L,IL6R,KCNJ5,KCNJ11,KCNK2,NEFH,NFIA,NPPA,PC,PDYN,PRKCZ,MTMR10,RGS4,SELL,FOXRED1,SCMH1,FAM208A,BEX4,SLC35A4,PITPNB,SLC30A4,TUBA1A" Coexpression M8320 Genes up-regulated in CD4 [GeneID=920] T cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABR,ADD3,BIN1,DGKZ,CDC14B,ARRB2,PLA2G4C,CADPS,ENTPD6,CDC25B,DLGAP1,ASIC3,IFFO1,SEC31B,PPP6R2,SPOCK2,DOCK2,TNK2,MRNIP,EN2,RASGRP2,PTK2B,FCGRT,FYB1,TRAF3IP2,SEPT9,KAT7,IL11RA,MX1,OCRL,PAX6,PLCD1,RPS20,RASA3,SGK1,SPTAN1,FAM168A,VAMP1,MCF2L,TCF7,SYNE1,TPM2,TUBB2A,GDPD5" Coexpression M7503 Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper) from germinal center. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,CC2D2A,ARMC12,ARHGAP5,ATP1A2,ADAM23,WASF1,LONRF2,CLU,SULT4A1,LRRC3B,SCRN1,HEPH,AK5,FGF14,HPCAL4,HRASLS5,GABRA5,SALL3,RAB30,GPR75,PSRC1,KLF12,HNMT,TLX1,CPT1C,ICA1,USP54,KHK,PACRG,MAP6,CNTN3,TMEM231,ITSN1,FUZ,DZIP1,ST5,MPRIP,SIK3,HEY1,RASD2,CCDC136,PORCN,TMEM163" Coexpression M5023 Genes up-regulated in comparison of SP1 thymocytes versus SP2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AS3MT,SEMA7A,ARNTL,ALDH7A1,ATP6V1G2,BAIAP3,CACNA2D1,ACY3,ABCC5,PLEKHO1,ENO2,IGSF6,REEP2,TVP23A,GAA,GGT7,COPS8,TDRKH,GRIA4,KCNK1,LSS,PTOV1,NUCB1,ZDHHC22,GLIPR1L2,SEPT4,EMID1,RTKN,SCN4B,SGK1,SHMT2,PKNOX2,SMARCE1,ARHGAP26,TCF4,TCF7L2,SPX,HEY1,PRRT1,CDK20,CLHC1,ZNF711,POLR3H,TMEM163" Coexpression M4524 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 48 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "CLK4,AMT,DGKD,ATP1A1,BCL7A,CFAP410,CAMK2G,NPIPA1,ZBED5,SH2B1,FAM169A,SNPH,PLEKHA1,RASGRP2,SARAF,OGA,FYB1,TMEM8B,MSL3,HSPA1L,MSL1,MYH3,ZNF862,NUMA1,CCSER2,RETREG1,SPATA6,PRKCZ,VPS13C,BSDC1,DCUN1D2,RPS20,RXRA,ATXN7,RASA3,SMARCE1,USP33,TSPYL2,ERBIN,VAMP1,BEX4,TSC1,ZBTB14,MARCH8" Coexpression M3084 Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus B cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,APBA2,CASK,ARNTL,ATP1A1,CDC25B,PLEKHB1,RAB33A,LRIG1,IPCEF1,HDAC4,KIAA0513,SPOCK2,OPTN,LPAR6,GOLGA7,STX2,FHL1,SEMA4D,TRMO,TRIM16,FYB1,FYN,RAPGEF6,HSPA1L,IL6ST,IL11RA,ITPKB,NELL2,PCSK5,PIK3R1,CCSER2,RETREG1,PLCL1,RGS10,FAM102A,TNIK,KIF21B,CLUAP1,TCF7,DOCK9,AKTIP,TIAM1,ATP6V0E2" Coexpression M7496 Genes down-regulated in SELL dim [GeneID=6402] NK cells: NCAM1+ [GeneID=4684] versus NCAM1- [GeneID=4684]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "TTYH1,SLC25A25,MTUS1,PI16,DDO,BCAS1,CPNE5,ADAM15,CA12,TBRG4,CHRNA4,LY86,CSF2RA,SLC25A18,DUSP9,CELSR3,RASGRP2,NCALD,IGSF6,EXTL1,SPSB4,B4GALNT1,GFRA1,HP,IRF8,KCNQ3,KIFC3,DDR2,OLR1,OPRL1,PLP1,RGS4,ATP8B4,RPS6KA2,FAM19A1,SELL,FUZ,SLC22A4,TEX2,SPTAN1,NECAB1,DAAM2,PRMT8,SIGLEC10" Coexpression M8133 Genes down-regulated in cytotoxic T cells: control versus treated with Akt inhibitor VIII [PubChem=10196499]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ASIC1,ESYT2,GOLGA7B,DGKD,ARRB1,ASGR1,ST3GAL5,CAMK2G,RCBTB2,FOXN3,ARHGEF6,ZFP28,PLXNA4,SV2A,COPS4,HVCN1,NEK6,SPIN1,MUM1,HMGCR,KPNA5,GPR155,MBP,MOV10,MIR4697HG,FXYD7,NPTX1,PDE4D,GNG2,XRN1,LRRN3,PTPRN2,IL17RB,CLSTN1,IGSF9B,SP4,SAMSN1,TBL1X,DOCK9,TP53BP1,TRPM2,MICAL1,GDPD5,HPS4" Coexpression M7159 Genes up-regulated in CD4 [GeneID=920] T cells treated with HDAC inhibitors: 2h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SFMBT2,MTMR3,CAPN3,CBFA2T2,CD81,ABCG2,DNAJB5,SLC4A7,CRMP1,ARHGEF10,DAPK1,KBTBD11,CDON,ATL1,TMEM164,SDCBP2,MTHFD2,STON1,TUBB2B,ITGAM,L1CAM,STMN1,CD200,MYO6,NCF2,P2RX7,PFKFB4,SSH1,SLC25A23,SYTL2,FNIP1,MYO18A,ST6GAL1,RCOR3,TEX2,KIF1B,SAMSN1,SYPL1,KIAA1107,AHCYL2,TGFBR3,TIAM1,ITM2C,CERS6" Coexpression M6264 Genes down-regulated in cortical thymic epithelial cells (cTEC) versus thymic macrophages. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "CPNE2,LRFN2,CASKIN1,WDR35,CC2D2A,ZNF687,KIF6,APC,CDC25B,SRSF11,COG1,NMT2,NCOR1,TM9SF4,TBC1D5,SMG7,DNM1,EIF4G1,SRPK3,ABCA8,OLFM1,FGFR1,POLK,TACC2,SMC2,ACSS1,VWA5A,GIT1,PFKP,PLEC,PLEKHB2,ARHGEF10L,RPS6KA2,FNIP1,DOCK10,SLC12A2,ZSWIM8,STAC2,GSE1,TACC1,SIN3B,TTC3,PITPNB,TMEM178A" Coexpression M3038 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACTN1,ACTN2,ADCY6,AMPD3,SFMBT2,DDX3Y,ATP1A1,SEC11C,MAP7,MAP4K4,CNN3,GUCD1,EIF4G2,RASGRP2,TUBA1B,TUBB3,SESN1,GGT5,TUBA1C,RAPGEF4,GSN,IL6ST,INPP5B,MATK,MX1,NFIX,CDIP1,PRKCB,SNRK,ZDHHC14,REV3L,RGS10,RPRD1A,RPS6KA2,SATB1,HES6,ST6GAL1,ST8SIA1,TBCEL,TNNT1,TTC3,TUBA1A,PHTF2,FRMD6" Coexpression M4097 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABR,APBB2,MARK4,N4BP2L1,MTMR7,C1orf52,CSF2RA,CYBB,GUCD1,PARD6A,G3BP2,ASB3,STARD3NL,SPEG,FER,PCYOX1,ATP2C1,GALC,SALL3,NEU3,TNRC6A,STARD3,IRF8,MSL1,MBP,CD200,SNX10,SMOX,DRAM2,RPE,MCMBP,FAM192A,SLC2A5,CDK5RAP2,STXBP1,ARC,FBXW11,ZEB1,DDHD1,TNFRSF1B,CDK20,WBP2,HPS4,SNX14" Coexpression M5472 Genes up-regulated in comparison of dendritic cells (DC) versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABHD6,ALCAM,DDO,PLA2G4C,CAMK2A,CBR1,CDC42BPB,PREPL,CYBB,DBT,SIDT2,PCOLCE2,BSCL2,GAA,TMEM8B,SEPT9,ADAP1,GRM3,ACOT7,ITPKB,MAOB,MATK,MEF2C,MKLN1,NRGN,OGDH,SMIM7,QDPR,ARHGEF10L,HUNK,CCDC92,SLC1A3,SLN,TMCC1,ZBTB43,SEPT8,STXBP1,ROBO3,TIAM1,TNS1,TST,PDSS2,CERS6,ST8SIA2" Coexpression M5999 Genes up-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 400min. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AS3MT,METAP1D,ADORA3,BCL2L2,BID,NAE1,C4orf33,AKAP7,C2CD2,IPCEF1,ARHGAP24,EARS2,TBC1D5,COPS7A,TMCC2,ABCC5,LPAR6,PCYOX1,NSG2,ZBTB45,FGFBP3,MBD1,ZNF862,IDNK,NUMA1,CHAMP1,PEX2,RAP1GAP,RGS3,CYB561D1,TMEM100,DGLUCY,FOXRED2,PPM1E,SEPHS1,SLC20A2,TET1,CAMTA1,EHBP1,SMUG1,RUNDC3B,LRTM2,MICAL1,AMN1" Coexpression M9847 Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AP2A2,TXNDC16,MRTFA,CDC14B,BBS2,ENTPD6,ARHGEF6,AATK,CSNK1E,CEP170,ANKRD46,TBC1D16,UBE2E3,FLYWCH1,TMEM175,POMT1,GALC,HPGDS,KDM2B,INPP1,KIFC3,NAT8L,MATK,NASP,PDE3B,C11orf49,PPP5C,FAM120C,OXR1,ZDHHC14,TRIM68,TMLHE,SGK1,SCMH1,KIF13A,SPART,SS18,SYPL1,DDHD2,ALG1,TCF7L2,TCF12,TPD52,PLD4" Coexpression M9414 Genes up-regulated in CD8A [GeneID=935] dendritic cells: untreated versus poly(IC). MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ABR,ALCAM,APBB2,ATP2B1,AZGP1,BCL7A,SYNJ2,RAB29,CDC25B,LY86,CRYM,PLCH2,SIPA1L1,PPP1R16B,HDAC9,RIPOR2,RHOBTB1,RASGRP1,FER,CSPG5,MPP6,ADAM28,GLDC,CBX1,GPM6A,MMP17,NRGN,PCDH9,PDGFRA,PKIA,NDUFS7,RGS4,RGS10,ST6GAL1,ST8SIA1,SLA,KIF21B,IZUMO4,SPP1,PEG10,TACC1,SYNE1,TJP1,UGT8" Coexpression M4720 Genes down-regulated in comparison of dendritic cells (DC) stimulated with R848 at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ESYT2,NRP2,CFLAR,IL33,SPAG9,MAP4K4,WHRN,ABCG1,PDE4DIP,MAMLD1,GOLT1B,EGR3,LINC-PINT,HSD17B14,DENND4A,RPS6KC1,SPSB4,IQCG,BRPF3,TOX3,TPPP,GRB10,GUCY1A1,GUCY1B1,MGC16275,NIM1K,IL12A,TTYH2,SCG3,NFE2L2,OXTR,SCHIP1,NUDT11,FNDC3A,SLC1A3,SLC2A5,CLUAP1,TAB2,ANKRD28,TAC3,ZFPM2,TPM2,CADM1,ADAMTS10" Coexpression M8093 Genes down-regulated in spleen B lymphocytes with IRF8 [GeneID=3394] knockout: marginal zone versus follicular. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "AP1B1,GOLGA7B,APAF1,PHYHD1,ZFYVE28,CD38,C1orf52,CCPG1,CNOT8,SLC4A8,CNRIP1,KIAA0040,CTNND1,DOCK4,ELMSAN1,KIAA0319,ZC3H11A,ADGRV1,FCGRT,KAT8,NELFCD,TMEM107,IQGAP2,GATM,WASHC2A,HMGB1,MDM4,MT3,TAGLN3,NOS1,GNG2,PMP22,PPM1E,CLUAP1,KLHL7,ALG1,TMEM9,TMOD1,TNS1,LMF1,SLC13A3,CFAP298,RNF103,FBXO36" Coexpression M3735 Genes up-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADRB2,EPB41L5,APOC2,ARRB1,CCAR2,GPR146,MTMR3,SLC16A4,LARGE1,ABCG2,SMARCAL1,RBM39,IP6K1,HP1BP3,BLOC1S6,PLEKHA1,POLK,GALC,GRIK5,SYNPO,HMGCL,IL6R,ITPKA,KHK,STMN1,ADAM11,MX1,IDNK,NEK1,OPA1,ANLN,PRODH,KHDRBS2,RPRD1A,RNH1,RPE,DGLUCY,SARS,MAST1,SEPT8,DNAJC9,P2RY12,TUBA1A,AAAS" Coexpression M9357 Genes down-regulated in day 7 memory B cells versus day 40 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ACADM,SLC12A5,FAM135A,ARRB2,BMPR1B,CAMK2G,ATRNL1,ARHGEF4,GUCD1,DMD,ATL1,STX2,GMPR2,REEP2,SPSB4,MEX3B,PCYOX1,SLC37A3,STARD10,LUZP2,GRK4,GSN,KHK,L1CAM,GPR155,SESN3,MYO6,TBC1D25,PFKFB2,PLEC,MAPK3,GRAMD1C,RAD17,RAP1GDS1,CLIP1,RTN1,TET1,CPEB4,DDHD2,ZMYND8,TUBA1A,JMJD1C,ZDHHC20,SSPN" Coexpression M5079 Genes up-regulated in comparison of memory CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574] versus naive CD8 T cells treated with IL4 [GeneID=3565] and IL7 [GeneID=3574]. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "OSBPL6,C1QTNF1,FAM135A,CASK,ARHGDIA,RNF182,CAMK2A,SYT6,MTMR7,CD86,LARGE1,CSF3R,SUSD5,TBC1D5,RIMS3,HS3ST4,HSD17B14,MFSD10,EFS,SDCBP2,JPH4,OS9,GNG4,GRM5,COQ10A,KCNC2,KCNJ11,CHIC1,MYO6,FXYD6,ABCB1,FXYD1,MARCH1,S100B,SMTN,ARHGEF40,SST,TAL1,CNTN2,TRH,KCNE5,RPRM,PLPPR5,CPNE4" Coexpression M9523 Genes up-regulated in CD5 T cells at acute infection with LCMV-Armstrong: effectors at day 15 versus memory at day 30. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "SNX30,BCAR3,BACH1,GPR146,BMP7,PRMT9,VSTM2A,SLC5A11,SRSF11,ZFYVE9,ABCG2,RCHY1,USP6NL,CEP170,FEM1B,OPTN,GCNT2,HPS5,KCNB1,CAMK2N2,P2RY1,PDE2A,ZNF655,RALGDS,RPE65,TMEM100,FBXW7,SLC6A8,SIRT2,CPEB4,MYO16,SOX15,LMO3,SRPK2,ZC4H2,RGL1,ANKRD12,TMEM121,GZF1,NR2E1,PRMT8,ZNF23,ZFAND5,JMJD1C" Coexpression M6276 Genes up-regulated in medullary thymic epithelial cells (mTEC): CD80 [GeneID=941] high versus low. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADCY2,GALNT13,ADRA1B,NT5C3B,BCAS1,PPFIA3,ATP1A3,FGF17,THSD7A,VSTM2A,CDH18,C2CD2,DUSP27,CLVS1,FABP7,STAU2,SYT17,OS9,GPM6B,LPAR4,GRIK1,HLF,HAPLN2,CDH20,C1orf194,MPP2,SAMD5,NDP,ALDH1L2,NRCAM,PCDH9,PDE1A,MAPK4,ZNF532,YJEFN3,IL17RB,PREX2,PKNOX2,NECAB1,HEY2,REEP1,LAMP5,ITM2C,SLC17A6" Coexpression M7430 Genes up-regulated in neuron cell line treated with interferon alpha for 12h: immature versus mature. MSigDB C7: Immunologic Signatures (v6.0) 9.13E-03 1.00E+00 4.94E-02 4.91E-01 44 200 "ADD1,AXIN2,ARHGAP20,CARNS1,AMPD3,ARRB1,HIP1R,ARHGEF10,KIAA0040,CYBB,RIPOR2,SPOCK2,KBTBD11,DMTF1,RASGRP2,MEX3B,HVCN1,SDCBP2,ZMYND11,RAPGEF6,OS9,GUCY1A1,ZDHHC15,SMAP1,L1CAM,MATK,P2RX7,ABCB1,SERPINI1,SYTL2,PTPN13,PTPRE,RASGRF2,SCG5,DZIP1,SLC14A1,DBNDD2,RAP1GAP2,SRPK2,C3orf70,SYNE1,AKNA,ARHGAP9,ITM2C" Coexpression 16574750-SuppTable2 Human StemCell_Song06_74genes GeneSigDB 9.22E-03 1.00E+00 4.99E-02 4.95E-01 16 56 "SYNJ2,CDH2,JAM2,SOCS5,SCRN1,ENO2,EFEMP1,DLC1,MEST,MN1,SYTL2,RGS4,SLC8A1,TPM1,UCHL1,VLDLR" Coexpression M1800 Genes up-regulated in ex-vivo colonic tissue after treatment with IL22 [GeneID=50616]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.22E-03 1.00E+00 4.99E-02 4.95E-01 16 56 "SLITRK1,APAF1,IL33,CD38,ARRDC4,ALDH1L1,FREM1,MFSD2A,HP,OLR1,OXTR,PFKFB3,PTX3,RTN1,AMER2,TAC1" Coexpression Atlas cerebral cortex cerebral cortex Human Protein Atlas 0.00E+00 0.00E+00 0.00E+00 0.00E+00 1024 1431 "DPF1,TTYH1,ABAT,DGCR6,KCNH8,ASPHD1,SYN3,ASIC2,ASIC1,CSMD2,GPRIN1,XKR4,CSMD3,FMNL2,ADARB2,KLHL32,TMEM132B,ELFN2,ADCY2,DSCAML1,SLITRK1,CCDC85A,ADCY8,GALNT13,RNF157,ADCYAP1R1,ADD2,SLC12A5,SORCS1,ERMN,PLEKHH1,ADORA1,UNC5A,PTCHD1,ADRA1B,LRFN2,BEND6,NLGN4X,SLC24A4,GPR158,SNX32,CASKIN1,PCDH19,AGT,KCTD16,OSBPL6,SORCS2,DISP3,LRRC7,SMIM17,C1QTNF4,CARNS1,MARCH4,PCDH10,GOLGA7B,UNC79,ALK,KCNT1,SYT13,PDZD4,BEGAIN,DOC2A,AMPH,KIF6,BIN1,LRFN1,DPP10,ANK2,PPFIA4,PPFIA2,CNIH2,CNTNAP1,APBA2,KCNAB2,APC,GAS7,APLP1,MAGEE2,VAT1L,AMER3,LRRC4C,BCAS1,PPFIA3,SHTN1,CPNE5,AQP4,SLC7A14,PPP4R4,TMEFF1,SPTBN4,ARHGDIG,RGS20,ARSF,CADPS,ASCL1,BRINP2,ASTN1,INSYN2B,TMEM108,ATP1A2,ATP1A3,ATP2B2,ATP2B3,RNF182,B3GALT2,CADM3,NOL4,ATP6V1G2,KIF1A,ADAM23,TTC9B,CARMIL3,ADGRB1,ADGRB2,ADGRB3,RGS11,HCN2,CDK5R1,SYNJ1,CACNA1I,CACNA1G,NIPA1,BSN,WASF1,MYRF,BAIAP3,CDK5R2,MMD2,CACNA1A,CACNA1B,CACNA1E,CACNB4,CABP7,DIRAS1,KALRN,HAP1,NGB,CAMK2A,CAMK2B,SYT6,VSTM2A,BRSK2,RHBDL1,SHISA7,CCK,CCKBR,SLC5A11,MTMR7,INA,P2RX6,TMEM257,SYNGR3,DGKI,CDH8,CDH10,DCLK1,CDH18,LGI1,DLGAP2,DLGAP1,CDR1,NOG,CRLF1,GPR37L1,CBARP,CHN1,CHRM1,PLEKHB1,CHRM4,SYNPR,CHRNA4,RAB3C,CHRNB2,NDST3,LHX2,DLGAP3,CPNE6,RAB33A,NRXN3,KIAA1549L,CLCN4,NRXN1,NRXN2,SLC24A2,TMEM59L,NGEF,VAX2,FAM19A5,SULT4A1,RAB26,TMEM155,IGLON5,CNR1,CNTFR,CNTN1,PCYT1B,AKAP6,CABP1,COL9A3,AKAP5,SLC4A8,GAL3ST1,TCEAL2,MYRIP,IGDCC3,CNRIP1,HS3ST5,SLC35F1,FAM171B,CRMP1,SLC32A1,C1QL2,GDA,CLIP3,CRYM,AATK,RGS6,FEZ1,LRRC3B,ATRNL1,GALNT9,CHD5,NCAN,RIMS4,PHACTR3,CNTNAP2,RASGEF1C,FAM169A,SLITRK5,PPP1R16B,CALY,ERC2,CMTM5,ARHGEF4,SLC45A1,CTNND2,NRSN1,RIMS2,ST18,FAM131B,CX3CR1,SEC14L5,NOS1AP,KIAA0408,DOCK4,SNPH,FRMPD4,KIAA0513,RASSF2,RIMS3,KCTD8,PHYHIP,DGKB,DGKG,SCRN1,SPOCK2,BRINP1,DCC,DNAJC6,JAKMIP2,ZNF804A,CNIH3,TIAM2,KIAA0319,MAGI2,TMEM130,LYPD1,PLPPR4,SNAP91,SV2B,SV2A,SRGAP3,NTM,AK5,TMCC2,ARNT2,KBTBD11,DLG2,DLG4,DLX1,GRIN3A,RAB39B,DNM1,HS3ST4,OLIG1,HS3ST2,NYAP1,RPS6KL1,CALN1,DYNC1I1,SHANK1,FAM57B,DPP6,SLC25A18,DRD1,DRP2,DSCAM,DTNA,EDIL3,ST8SIA3,SEZ6L2,TSPAN5,FAM135B,ATL1,EEF1A2,CNNM1,RASGRP1,FSD1L,CACNG7,EFNB3,CELSR3,GPR61,MRO,TMEM132E,ELAVL2,ELAVL3,ELAVL4,TMEM35A,OLIG2,ENO2,SEZ6,EPHA5,EPHB1,ANKRD13B,APC2,TMEM74,ETV1,EXTL1,CEND1,NRN1,REEP2,CLVS1,FABP7,CACNG3,CACNG2,ZIC4,TUBB3,TUBB4A,CORO2B,SLC9B2,MED12L,FGF1,OLFM1,SPSB4,FGF12,FGF14,ACTL6B,HPCAL4,FOXG1,C1orf61,CAP2,AGAP2,PSD2,SGIP1,SYT3,DPYSL4,NBEA,RASL10A,KHDRBS3,DACH2,CGREF1,CSPG5,DLL3,PNMA2,FUT9,B3GAT1,ADGRA1,HHIPL1,TMEM151A,TBR1,NRG3,BRSK1,TVP23A,PHYHIPL,MEGF11,DKK3,MEGF10,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,CHL1,GABRB1,GALNT15,GABRB3,GABRG1,GABRG2,ILDR2,FAM184B,GAD1,GAD2,B4GALNT1,JPH4,NKX6-2,ARPP21,GALR1,SALL3,GAP43,SYT17,ATP8A2,SRRM4,WASF3,CPLX2,CPLX1,DNER,FAXC,TUBA8,GDF1,GPR162,CYP46A1,GFAP,PCDH17,HEPN1,C1QL1,KIRREL3,RUNDC3A,NTNG2,TTBK1,RND1,GLRB,GPR75,PCDH11X,AIFM3,MAP7D2,INSM2,LUZP2,PCSK1N,KCNMB4,DCLK2,RAB40B,GNAO1,GNG3,GNG4,PSRC1,CNDP1,GPM6A,GPM6B,DIPK1C,PRLHR,GPR12,CCDC184,B4GALNT4,ADAP1,GPR19,GPR22,MCHR1,GPR26,GPR37,CECR2,PCLO,RAPGEF4,STMN2,TPPP,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,SERP2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPRT,KIF3A,FAM19A2,RNF165,PTPN5,IL1RAPL1,SOX21,LINGO1,FAM107A,RNFT2,TMEM179,FAM222A,CELF3,UBE2QL1,IGSF21,PADI2,NXPH3,NXPH2,GPR45,FRMD5,HRH3,INSYN1,HAPLN2,ACOT7,SCRG1,HMX1,HPCA,C9orf129,NEGR1,CPT1C,OPALIN,TCEAL6,CELF5,HTR2A,HTR5A,ATCAY,BTBD17,RAB41,C2orf72,GAREM2,ZIC5,NIM1K,KNDC1,DISP2,HES5,LIX1,TMEM240,BRINP3,RIPPLY2,SLC6A17,TUBB2B,LRRTM3,LRRTM1,C2CD4C,ITPKA,KCNA1,KCNA2,OLFM3,KCNA4,CDH20,KCNB1,KCNC1,KCNC2,KCND2,KCNF1,GPR62,KCNH1,CLVS2,KCNJ3,KCNJ4,KCNJ9,KCNJ10,KCNN1,KCNN3,KCNQ2,KCNQ3,CREG2,KIF5A,KIF5C,KLRC2,KLRC3,L1CAM,TTYH2,LRRC4B,CAMK2N2,INSYN2,SFXN5,MSANTD3-TMEFF1,FGFBP3,LSAMP,C2orf80,MAG,NAT8L,MAP2,MAP6,MAPT,MATK,MBP,SYT9,ADAM11,IL17D,LRP1B,SHC3,SRSF12,MGAT3,SCAMP5,MMP16,MMP17,MOBP,MPP2,ERICH3,CPNE9,MSI1,JAKMIP3,ADAM22,MT3,SCG3,TAGLN3,DDX25,CTNNA3,RSPO2,C10orf105,SAMD14,HS6ST3,LINC00672,PABPC1L2A,MYT1,TCEAL5,BEX5,FXYD7,NAP1L2,NAP1L3,NCAM1,NCAM2,ZC3H12B,RCOR2,NEFM,NELL1,NELL2,NEUROD1,NEUROD2,SLCO1C1,NKX2-2,NNAT,NPY,NOVA1,NOVA2,LRIT2,NPTX1,NPTX2,NRCAM,NRGN,HCN1,NTRK2,NTRK3,KSR2,IGSF11,GPR88,OLR1,OMG,OPCML,OPRL1,CLDN11,GPR137C,ZDHHC22,KCNK10,TREM2,SNTG1,PAK3,PALM,CNTN3,PAX6,PCDHGC3,PCDH8,PCDH9,PCSK1,PCSK2,PDE2A,PDE1B,PIRT,PDYN,SLC10A4,GPR173,GPR85,TMOD2,BEST3,DUSP26,NLGN3,GDAP1L1,SERPINI1,NALCN,SEMA5B,CAMKV,TMIE,ANLN,SNX10,FAM216A,ST8SIA5,JAKMIP1,SMOX,PLP1,HMGCLL1,ASPDH,PLXNB3,PURG,PNMA3,PMP2,PSAT1,SCHIP1,NECAB2,MAGEL2,SEPT4,PACSIN1,FA2H,FAT3,NXPH1,POU3F2,POU3F4,FSD1,TMEM235,PPP2R2B,PPP2R2C,LRRN3,NKAIN4,RANBP3L,VSTM2L,PRKACB,PRKAR1B,PRKCB,RAB39A,PRKCG,PRKCZ,MAPK4,MAPK10,DIRAS2,SMIM10L2B,GDPD1,KLK6,PSD,MDGA2,PLPPR1,PTPRD,PTPRN,PTPRN2,PTPRZ1,TMEM145,NKAIN1,STRC,RAB3A,SLC25A48,SH3TC2,IQSEC3,SLC25A41,RAP1GAP,NWD1,RASGRF1,RASGRF2,DBX2,FEZF2,KHDRBS2,SLC6A15,CRTAC1,ZMAT4,PRRT2,RFX4,RGR,RGS4,RGS7,KCTD17,TTLL7,RIT2,RLBP1,SEC61A2,NUDT11,ROBO2,ROM1,RORB,TMEM206,MRAP2,RPE65,SNX22,BAALC,GLDN,SGSM1,RIMKLA,MAP6D1,PLPPR3,SYNDIG1,PAQR6,SOX8,HSD11B1L,TUNAR,KCNIP3,YJEFN3,KCNIP2,KCNIP1,RTN1,STX1B,S100B,AMER2,CSRNP3,DRAXIN,SCN2A,SCN2B,SCN3A,LRRTM4,FAM19A1,SCN8A,HES6,ASIC4,ELMOD1,TMEM200C,TRIM46,STUM,SCG5,KIF21A,SH3GL2,SH3GL3,PPM1E,NTNG1,SHC4,SLITRK3,CNKSR2,BCAN,SYBU,NLGN1,CTXN2,SLC1A2,ZNF365,SLC1A3,SLC4A3,SLC1A6,FAM81A,RPH3A,SLC6A1,LRRC55,SLC6A7,SLC6A11,SLC8A2,YPEL4,SLC8A3,TRIM67,SHANK2,RTP5,NAPB,TMEM132D,SLCO1A2,SPHKAP,LGI3,SLIT1,CXXC4,MAST1,SORCS3,DMRTC1,MYH15,RIMS1,SNAP25,SNCB,SNCA,FAIM2,MYO16,UNC80,SCN3B,SOX1,MYT1L,SOX2,KIF21B,SOX10,SOX11,DOK5,NMNAT2,LHFPL4,HECW1,BEX1,MCF2L2,NPAS3,DDN,NFASC,LMO3,C11orf87,CLASP2,CLSTN2,COLGALT2,SMOC1,SST,SSTR1,SSTR2,NKAIN2,LRRC4,NACAD,NCDN,ELOVL4,STAC2,STX1A,SEPT3,STXBP1,AJAP1,ACSBG1,NECAB1,SYT11,MLC1,ABCC8,ZFR2,RHBDL3,FNDC9,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT4,SYT5,TAC1,POPDC3,TMEM178B,UNC5D,CNTN2,ADGRL3,KIAA1107,ANO4,WSCD1,ACSL6,NEU4,SATB2,CUX2,TRIM2,PCDHGC5,PCDHGB6,WDR7,PCDHGB1,PCDHGA10,PCDHGA9,PCDHGA3,NAT16,PCDHGA1,PHF24,TMEM151B,RALYL,PCDHB10,FAM189A1,PCDHB9,PSD3,PCDHA7,PCDHA6,PCDHA5,PCDHA1,RNF175,TMEM121,KHDC1,CHST8,CRB1,CDH22,FBXL16,ENHO,HEY1,RELL2,ICAM5,TLL2,BHLHB9,NR2E1,ANKRD24,KCTD2,PRRT1,CSMD1,TNR,SEZ6L,DOK6,PRMT8,TRO,NTSR2,KCNE5,TMPRSS5,CA14,LRTM2,RFTN2,PRR18,TUBB2A,TMEFF2,HEPACAM,RPRM,FAM155A,CLEC2L,UCHL1,FRRS1L,UGT8,FLRT1,FAM181B,MGAT5B,VGF,VSNL1,RBFOX3,P2RY12,CLIP2,WNT7A,ETNPPL,KCNK12,PCDH20,ZIC1,ZIC2,ZIC3,MICU3,TRIM9,ELFN1,FMN2,PLPP4,NDRG4,CRB2,MKRN3,TCEAL7,CELF4,AMZ1,FSTL5,TMEM198,DPYSL5,ANKS1B,LAMP5,PLPPR5,SLC30A3,CA10,CADM2,LRP8,SHD,RGMA,STMN4,STOX2,XKR7,TMEM178A,SCG2,PCDH15,GAL3ST3,NAV3,SLC17A7,PPP1R3F,SLC17A6,RGS7BP,PAK5,TMEM63C,GJC2,CAMK1G,SLC39A12,PIANP,NETO1,CBLN2,AP3B2,ST8SIA2,SLC4A10,FAM181A,CPNE4,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 5.73E-86 2.92E-82 1.46E-82 1.33E-81 438 1070 "DPF1,ASIC1,CSMD2,CSMD3,NDRG3,TMEM132B,ADCY5,SLITRK1,ADCY8,SLC12A5,GRAMD1B,KIDINS220,GPR158,CASKIN1,NR0B1,HFM1,SMIM17,PCDH10,GOLGA7B,UNC79,ANK1,ANK3,PI16,PPFIA2,APBB2,LRRC4C,ASCL1,DNAH17,PCDHGB4,CHRD,ATP1A3,ATP2B1,NOL4,DOCK11,TTC9B,ADGRB1,ADGRB3,BCL7A,FGF17,CDK5R1,SCAPER,CACNA1G,CACNA1A,CACNA1B,CACNA1E,ZNF555,CAMK2B,CAMK2G,VSTM2A,HIP1R,RUNX1T1,PRC1,RGN,INA,SEPT7,REPS2,LONRF2,CDH8,CDH18,EVI5L,ADGRG1,SRSF11,CHGA,SYNPR,KMT2C,RAB33A,KIAA1549L,NRXN1,NRXN2,TMEM59L,QKI,NIPBL,CNN3,CNTN1,IGDCC3,CRMP1,ANKRD44,CSNK1E,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,CTNND2,RIMS2,ST18,CCDC144A,KIAA0408,RIPOR2,HDAC4,SPOCK2,BRINP1,DBI,ZNF804A,ZEB2,RUSC2,COPS7A,CEP170,TMEM130,SNAP91,SPOCK3,NTM,GRIN3A,DNM1,OLIG1,DPP6,ATN1,EBF1,SEZ6L2,FAM135B,EEF1A2,EEF1D,CACNG7,PLXNC1,TMEM132E,RASA4,TENM1,ELAVL2,ELAVL3,ELAVL4,RGS17,STARD3NL,EMX2,EN2,OLIG2,ENO2,DMTN,SEZ6,EPHA5,RAB9B,CEP85L,NRN1,NSRP1,FABP7,CACNG3,CACNG2,TUBB3,TAOK3,RACK1,FDFT1,KIAA1109,OLFM1,FGF12,C1orf61,SYNCRIP,SGIP1,SYT3,NBEA,PDLIM5,NSG2,CSPG5,NSG1,DLL3,ABLIM2,OGA,FYN,ZMAT1,GABRA1,GABRB1,GABRB3,GABRG1,GABRG2,FAM184B,GAD1,JPH4,ARPP21,GAP43,SEPT9,SRRM4,GART,DNER,FAXC,PCDH17,RUNDC3A,NTNG2,ZNF276,RAB30,TOX3,TNRC6A,MAP7D2,PCSK1N,GNAO1,GNG3,GPD1,GPM6A,GPM6B,B4GALNT4,GPR17,GRK4,STMN2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRM5,KIF3A,FAM19A2,PTPN5,CELF3,TOX2,PACSIN2,ACOT7,SCRG1,NEGR1,HSF2,SHISA6,HSP90AA1,CELF5,HTR2A,ATCAY,HES5,BRINP3,JAK1,KCNC2,KCND2,KCNK2,KCNMA1,CREG2,KIF5C,KLRC2,STXBP5,L1CAM,LRRC4B,STMN1,VWA5A,FGFBP3,NCOA7,LSAMP,C2orf80,ASPRV1,PIK3AP1,GPR155,MAOB,MEST,MMP17,MOBP,CD200,MSI1,MT3,SCG3,NEXMIF,NACA,BEX5,FXYD7,NAP1L1,NAP1L2,NCAM1,NELL1,NELL2,NFIA,NFIX,NKX2-2,NNAT,CNOT4,NPY,NOVA1,NTRK2,NTRK3,KSR2,OPCML,OXTR,PBX1,PCDH9,PCSK2,PDE4A,PDGFRA,GPR85,TMOD2,GDAP1L1,SERPINE2,SERPINI1,PIK3R1,PKM,PLP1,SLC25A23,PLXNB1,PMP2,SCHIP1,NXPH1,C19orf57,POU6F1,MED1,PPP2R2B,PPP2R2C,LRRN3,NKAIN4,PRKACB,PKIA,PRKCZ,HYDIN,DIRAS2,MASP1,MDGA2,PTCH1,PLPPR1,PXK,PTN,STK32A,PTPRZ1,TMEM145,CCDC40,ZNF793,RALGDS,RAP1GAP,RASGRF1,ARID4A,VEPH1,BSDC1,CRTAC1,ZYG11B,REV3L,RIT2,SLC25A36,RORB,KIAA0895L,LRRK2,RPS20,SYNDIG1,SOX8,RTN1,RYR3,S100B,AMER2,MAPK12,ATXN2,SCN2A,SCN2B,SCN3A,ASIC4,SOX6,TRIM46,HSPA4L,SCG5,PPP1R9A,SLITRK3,BCAN,SYBU,SLC1A3,EPN2,SLC8A3,SIRT2,CCDC88A,TRIM67,SHANK2,SLC22A4,CPEB4,ZFP1,MAST1,LIMCH1,RIMS1,SNAP25,MAPKBP1,KIF13A,FAIM2,LMBRD1,UNC80,USP33,SCN3B,DOP1A,MYT1L,SOX2,KIF21B,SOX10,SOX11,DOK5,HECW1,BEX1,SPTB,NPAS3,C11orf87,CLASP2,SMOC1,SST,STX1A,SEPT3,GSE1,ABCC8,SYT1,SYT5,TAC1,TAL1,CAMSAP2,KIAA1107,TCF4,SIN3B,TCF12,RALYL,ARHGEF12,SIK3,ZFPM2,SPX,ITGB3BP,AP4E1,CDH22,TMOD1,RIMBP2,CSMD1,TNS1,TP53BP1,RUNDC3B,RFTN2,HSPBP1,TMEFF2,FAM155A,UBTF,UCHL1,PLPPR2,CCDC136,VSNL1,TSPAN11,ZFP37,PLPP4,MKRN3,CELF4,REEP1,FSTL5,ZNF184,ANKS1B,PLPPR5,ZFAND5,CA10,CADM2,SLC38A1,STMN4,PRDM8,TUBA1A,SCG2,PCDH15,KCNAB1,ITM2C,DNAH10,RTN4,PAK5,JMJD1C,NETO1,DPF3,SLC4A10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.96E-80 1.00E-76 3.34E-77 3.04E-76 200 313 "ASIC1,CSMD2,SLITRK1,SLC12A5,GRAMD1B,CASKIN1,NR0B1,SMIM17,PCDH10,GOLGA7B,UNC79,ANK3,PPFIA2,LRRC4C,ASCL1,PCDHGB4,CHRD,ATP1A3,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,SCAPER,CACNA1A,CACNA1B,CACNA1E,CAMK2B,CAMK2G,VSTM2A,HIP1R,RUNX1T1,RGN,INA,SEPT7,LONRF2,CDH8,EVI5L,ADGRG1,SRSF11,SYNPR,RAB33A,KIAA1549L,NRXN1,NRXN2,QKI,CNTN1,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,CTNND2,RIMS2,ST18,CCDC144A,BRINP1,ZNF804A,SPOCK3,NTM,OLIG1,DPP6,RASA4,ELAVL3,ELAVL4,EN2,OLIG2,DMTN,SEZ6,RAB9B,FABP7,CACNG3,TAOK3,FGF12,C1orf61,SGIP1,SYT3,NSG2,CSPG5,NSG1,DLL3,ZMAT1,GABRA1,GABRB1,GABRG1,GABRG2,JPH4,ARPP21,GAP43,DNER,PCDH17,MAP7D2,GNG3,GPM6A,GPM6B,STMN2,GRIA1,GRIA2,GRIA4,GRIK2,GRIK3,GRM5,FAM19A2,PTPN5,SCRG1,NEGR1,SHISA6,HSP90AA1,BRINP3,KCND2,KLRC2,LRRC4B,STMN1,FGFBP3,NCOA7,ASPRV1,GPR155,NEXMIF,NCAM1,NELL1,NELL2,NFIA,NFIX,NKX2-2,NNAT,NOVA1,NTRK3,KSR2,OPCML,PCDH9,PDE4A,PDGFRA,SERPINE2,SERPINI1,PLXNB1,PMP2,NXPH1,C19orf57,MED1,PPP2R2C,LRRN3,HYDIN,PTCH1,PLPPR1,PXK,PTN,PTPRZ1,CRTAC1,RIT2,RORB,SOX8,RTN1,RYR3,S100B,AMER2,SCN2A,SCN3A,ASIC4,SOX6,PPP1R9A,BCAN,SLC1A3,EPN2,CCDC88A,TRIM67,LIMCH1,RIMS1,SNAP25,FAIM2,UNC80,MYT1L,SOX10,DOK5,NPAS3,SMOC1,SST,SYT1,SYT5,KIAA1107,TCF4,RALYL,CSMD1,RUNDC3B,TMEFF2,FAM155A,VSNL1,PLPP4,CELF4,REEP1,FSTL5,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PCDH15,PAK5,DPF3,SLC4A10" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 9.24E-75 4.71E-71 1.03E-71 9.36E-71 372 895 "DPF1,CPNE2,TTYH1,SYN3,NCKAP5,FMNL2,KLHL32,GALNT16,SLITRK1,RNF157,ADCYAP1R1,PLEKHH1,PTCHD1,PCDH19,WDR35,TAOK1,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,EPB41L5,APLP1,MAGEE2,PHYHD1,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,ASCL1,NCOA1,ASTN1,ATP2B2,CADM3,KIF1A,ADAM23,CARMIL3,ADGRB3,FGF17,PROM1,DST,JAZF1,SGCE,CACNA1A,THSD7A,DIRAS1,HAP1,PTBP2,VSTM2A,C1orf52,CDK11B,CDC25B,LONRF2,CDH2,CDH8,EVI5L,MAGI1,NUMBL,ADGRG1,SRSF11,JAM2,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN1,NRXN2,DNAJB5,QKI,IGLON5,ARHGEF6,IQCK,WHRN,COL4A5,LETMD1,SLC4A8,ACBD5,NECTIN3,SLC35F1,FAM171B,CREB5,CRMP1,AATK,CSF2RA,FEZ1,NCAN,CNTNAP2,SLITRK5,ERC2,CTNND2,RIMS2,PPP6R2,ST18,PYGO1,KATNAL2,TOX,PHF19,KIAA0586,DGKB,SCRN1,BRINP1,DNAL1,DCC,JAKMIP2,MYEF2,RUSC2,FBXO25,DDX46,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,RAB39B,DMD,CD99L2,SHANK1,CASP8AP2,DTNA,MAMLD1,FSD1L,CACNG7,PLXNC1,ELAVL2,ELAVL3,CERCAM,ELAVL4,RGS17,BSCL2,TMEM35A,EMX2,OLIG2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,ADGRV1,CLVS1,NSRP1,FAM198B,FABP7,ZIC4,TUBB3,TAOK3,ATP8A1,CHST15,SPSB4,FGFR3,FOXG1,DPYSL4,ZNF605,FUT9,B3GAT1,NRG3,PHYHIPL,ILDR2,GAD1,SRRM4,ACSS1,KIAA1841,FAXC,GFRA1,PPARGC1A,RUNDC3A,MAP7D2,DCLK2,GNG3,GPM6A,GPM6B,DIPK1C,TDRKH,PCLO,STMN2,GRIK2,CACFD1,CIT,RNF165,MFSD2A,SOX21,RNFT2,CELF3,TOX2,FRMD5,DDX19B,KLF12,IGFBPL1,HPCA,USP51,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,HES5,BRINP3,TUBB2B,LRRTM1,KCNH2,KCNN3,KIF5C,KTN1,L1CAM,LSAMP,LSS,MAP2,MARK1,SHC3,PPM1L,MSI1,ADAM22,NRBP2,SCG3,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NASP,NCAM1,NCAM2,NEFM,NELL2,NFIA,NNAT,NOVA1,SLC11A2,NRCAM,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,SEMA5B,TMEM38A,GPSM2,SLC25A23,PLXNB1,SPATA6,SLC36A4,FAT3,POU6F1,EPDR1,MAPK10,PROX1,GDPD1,MDGA2,ELOVL2,PTPRD,EML5,PTPRZ1,RAD51D,FAM184A,ENOX1,ARID4A,FEZF2,GAL3ST4,PRRT2,RFX4,RFX5,GSTCD,TMEM206,SGSM1,ADAL,MEG3,RTKN,CLIP1,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,LINC00461,SOX6,ASRGL1,HSPA4L,SCG5,ZFP30,KIF21A,PPP1R9A,PPM1E,ARX,FBXO11,FHOD3,NLGN1,SLC1A3,FAM214B,CXXC4,GKAP1,MAST1,SORCS3,SMARCD3,SNAP25,MAPKBP1,TMCC1,TRERF1,SOX2,SOX5,SOX11,GLT8D1,LHFPL4,KIF1B,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,SEPT3,GSE1,FAM168A,SYT11,FGD4,SYNE2,RHBDL3,SYN1,SYP,ASTN2,ATP11A,TACC1,SEMA4A,MCF2L,TMEM178B,ACSL6,CUX2,TCF7L2,TRIM2,AZIN2,TMEM151B,PSD3,FRYL,AHCYL2,CCDC173,AKTIP,THRA,NACC2,TJP1,DDHD1,NR2E1,NR2C2,PRMT8,SSBP2,TUB,TUBB2A,SLAIN1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZIC1,ZIC3,ZNF23,TRIM9,FMN2,LYPD6,CELF4,REEP1,DPYSL5,STMN4,STOX2,TUBA1A,GAL3ST3,WNK2,FZD3,ST8SIA2,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.01E-74 5.13E-71 1.03E-71 9.36E-71 172 255 "ASIC1,CSMD2,CSMD3,SLITRK1,SLC12A5,SMIM17,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,CHGA,SYNPR,KIAA1549L,NRXN1,NRXN2,TMEM59L,CNTN1,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,KIAA0408,SPOCK2,BRINP1,ZNF804A,RUSC2,TMEM130,SNAP91,SPOCK3,GRIN3A,DNM1,OLIG1,DPP6,SEZ6L2,EEF1A2,RASA4,TENM1,ELAVL3,ELAVL4,EN2,OLIG2,ENO2,DMTN,EPHA5,FABP7,CACNG2,TAOK3,OLFM1,FGF12,C1orf61,NBEA,NSG2,NSG1,GABRA1,GABRG1,GABRG2,GAD1,JPH4,GAP43,SRRM4,DNER,PCDH17,RUNDC3A,MAP7D2,PCSK1N,GNAO1,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,GRM5,KIF3A,FAM19A2,PTPN5,CELF3,NEGR1,SHISA6,HSP90AA1,CELF5,ATCAY,BRINP3,KCND2,STMN1,CD200,NEXMIF,BEX5,FXYD7,NCAM1,NELL1,NELL2,NNAT,NOVA1,KSR2,OPCML,PDGFRA,GDAP1L1,SERPINI1,PLP1,NXPH1,LRRN3,PRKACB,PKIA,PRKCZ,DIRAS2,PLPPR1,REV3L,RIT2,RORB,KIAA0895L,RTN1,SCN2A,SCN3A,ASIC4,SCG5,TRIM67,CPEB4,MAST1,LIMCH1,SNAP25,MAPKBP1,SCN3B,MYT1L,BEX1,C11orf87,CLASP2,SST,STX1A,SEPT3,SYT1,SYT5,TAC1,KIAA1107,RALYL,CSMD1,RUNDC3B,TMEFF2,UCHL1,PLPPR2,CCDC136,VSNL1,CELF4,REEP1,FSTL5,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 7.83E-73 3.99E-69 6.66E-70 6.07E-69 294 629 "ASIC1,DSCAML1,KIAA1211,KIDINS220,SYT13,BIN1,CDC42BPA,ANK2,ANK3,PPFIA2,APBA2,APLP1,CADPS,ASCL1,DACT3,ATP2B1,NOL4,TTC9B,ADGRB3,CDK5R1,SCAPER,CACNA1G,GPC2,CACNA2D1,CALB2,THSD7A,SPAG9,RUNX1T1,CCNH,INA,CBFA2T2,SEPT7,CDH2,DCLK1,ADGRG1,CHGB,NDST3,CLCN4,NRXN1,NRXN2,CNGA3,ZNF521,CRMP1,SLC32A1,AATK,CSNK1E,NCAN,PLXNA4,NRSN1,RIMS2,ST18,KIAA0408,TCAF1,KIF26A,BRINP1,DCC,PITPNC1,DNAJC6,JAKMIP2,ZEB2,ELMO1,CEP170,GSDME,SV2A,NTM,GRIN3A,CPEB2,DPYSL2,DSCAM,EBF1,SEZ6L2,OPTN,EFNB3,SUGP2,KMT5B,ELAVL2,ELAVL3,ELAVL4,USPL1,EMX2,EN2,EPB41,DMTN,SEZ6,ANKRD13B,EFS,SPEG,NRN1,CLVS1,TUBB3,TAOK3,MED12L,FGF14,AMOTL2,MEX3B,AFF2,NBEA,NSG2,DACH2,NSG1,DLL3,PNMA2,FUT9,B3GAT1,DOT1L,PHYHIPL,GABRA1,GABRB3,GABRG2,GAD1,GAD2,NKX6-2,GAP43,SRRM4,KIAA1841,DNER,MMADHC,GFRA1,C1QL1,NTNG2,TCERG1,SPIN1,MSL3,GLUL,PCDH11X,DCLK2,GNAO1,GNAS,GNG3,GPM6A,STMN2,GRIA2,C1QL4,GRIA4,GRIK2,FAM19A2,TMEM25,PSIP1,GUCY1A2,CELF3,UBE2QL1,ZHX1,FRMD5,IGFBPL1,NEGR1,HSF2,HSP90AA1,CELF5,ATCAY,SHISAL1,SCRT2,INSM1,TUBB2B,KCNMA1,KIF5C,KLC1,L1CAM,STMN1,LMO1,MAP4,MAP6,MARK1,MEIS2,SRSF12,CD200,SAMD5,MSI1,PTOV1,SCG3,TAGLN3,HS6ST3,MYO5A,NAP1L3,NCAM1,NEFM,NELL1,NELL2,NEUROD1,NEUROD2,NFIX,NHLH1,NKX2-2,NNAT,NOVA1,GPR137C,PAK3,PBX1,PCDH9,PCSK1,GNG2,GDAP1L1,PKM,FTO,SLC25A23,SCHIP1,POU3F2,POU6F1,PPP3CB,PRKACB,PKIA,PRKCB,MAPK8,NDUFS7,PSMA6,MDGA2,PLPPR1,PTPRD,PTPRN2,PTPRO,PID1,RALGDS,ARID4A,REV3L,PRRT2,RGS4,ZFHX4,KLHDC8A,ROBO2,RPS6KA2,RPS20,RTN1,AMER2,CSRNP3,ATXN2,SCN2A,SCN3A,HES6,SMPD3,ASIC4,SOX6,MRAS,SCG5,SYBU,WDR47,SHANK2,NAPB,EPC1,CXXC4,SMARCE1,RIMS1,TMCC1,MYT1L,KIF21B,SOX11,ZBTB43,CLASP2,SEPT3,GSE1,SYT1,SYT4,SYT5,ROBO3,TAL1,CNTN2,KIAA1107,ZEB1,TCF12,CLASP1,PSD3,DICER1,ZFPM2,CRB1,THRA,RBFOX2,SEZ6L,DOK6,RGMB,FNDC5,RUSC1,HSPBP1,TUBB2A,FAM155A,UCHL1,TSPAN11,MICU3,FMN2,NDRG4,CELF4,ANKS1B,ZNF195,PRDM2,SHD,SLC38A1,STMN4,PRDM8,TUBA1A,TMEM178A,SCG2,TMEM163,PCBP4,SLC17A6,PAK5,CBLN2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.55E-70 7.93E-67 1.13E-67 1.03E-66 197 334 "ADARB2,KLHL32,TMEM132B,TMCC3,SLC12A5,KIDINS220,PCDH10,SYT13,CDC42BPA,ANK2,ANK3,PPFIA2,APLP1,APP,SHTN1,CADPS,B3GALT2,NOL4,CDK5R1,SCAPER,GPC2,CACNA1E,KALRN,RUNX1T1,INA,SEPT7,LONRF2,DCLK1,CHGA,CHGB,NRXN1,NRXN2,DNAJB5,CNTN1,PREPL,AKAP12,CRMP1,NCAN,PLXNA4,SDC3,ERC2,RIMS2,KIAA0408,RIMS3,DAPK1,DCC,DNAJC6,MYEF2,CEP170,SNAP91,NTM,ARNT2,DNM1,DPP6,OPTN,KMT5B,PLXNC1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EN2,EPHA5,ERBB4,FABP7,TUBB3,TAOK3,FGF13,IP6K2,NBEA,NSG2,CELF1,NSG1,FUT9,PHYHIPL,DKK3,GABRB3,JPH4,GAP43,SRRM4,DNER,FAXC,GFRA1,TOX3,HTATSF1,GNAO1,GNG3,PRRC2B,GPM6A,STMN2,GRB10,GRIA2,CELF3,TOX2,NEGR1,SHISA6,C5orf24,INSM1,KIF5C,KLC1,L1CAM,LSAMP,MAP6,MARK1,CD200,TCEAL5,BEX5,NAP1L2,NAP1L3,NCAM1,NEFM,NNAT,PBX1,PCSK2,SLC10A4,GNG2,TMOD2,CDK14,SLC25A23,PDZRN4,FAT3,POU3F2,LRRN3,PRKACB,PKIA,MAPK8,PTPRD,PTPRN2,PTPRO,ZNF793,RALGDS,ARID4A,REV3L,PRRT2,ZFHX4,ROBO1,ROBO2,KIAA0895L,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SMPD3,ASRGL1,SCG5,CPEB3,FBXO11,WDR47,RUFY2,CCDC88A,SHANK2,NAPB,CPEB4,SCN3B,MYT1L,KIF21B,SOX11,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,CLASP2,SEPT3,SYT1,SYT4,TAC1,TACC1,TMEM178B,KIAA1107,EHBP1,PSD3,CSMD1,RBFOX2,SEZ6L,RUNDC3B,RUSC1,TTC3,TUBB2A,TMEFF2,CADM1,UCHL1,RICTOR,CELF4,REEP1,DPYSL5,ANKS1B,LRP8,STMN4,TUBA1A,MVB12B,PAK5,CERS6,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.06E-68 1.05E-64 1.31E-65 1.19E-64 317 733 "DPF1,TTYH1,ABAT,SYN3,ABHD6,NCKAP5,GALNT16,SLITRK1,CCDC85A,RNF157,ADCYAP1R1,PTCHD1,PCDH19,WDR35,SEMA6A,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,EPB41L5,APLP1,MAGEE2,PHYHD1,LRRC4C,SHTN1,MADD,RGS20,NCOA1,ASTN1,CADM3,KIF1A,ADAM23,CARMIL3,ADGRB3,PROM1,BMPR1B,DST,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,HAP1,VSTM2A,CDC25B,LONRF2,CDH2,CDH8,EVI5L,NUMBL,FOXN3,JAM2,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN1,NRXN2,CLTB,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,SLC4A8,SLC35F1,FAM171B,CREB5,CRMP1,AATK,CSF2RA,FEZ1,NCAN,CNTNAP2,SLITRK5,ERC2,RIMS2,PPP6R2,ST18,PYGO1,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,JAKMIP2,RUSC2,FBXO25,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ELAVL2,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,ADGRV1,FAM198B,FABP7,TUBB3,TAOK3,ATP8A1,CHST15,FHL1,FOXG1,DPYSL4,NBEA,NSG1,FUT9,NRG3,PHYHIPL,GABRB3,ILDR2,SRRM4,ACSS1,FAXC,GFRA1,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,GPM6B,DIPK1C,TDRKH,PCLO,STMN2,GRIK2,CACFD1,RNF165,MFSD2A,SOX21,CELF3,TOX2,FRMD5,KLF12,AGBL5,IGFBPL1,HPCA,USP51,NEGR1,CPT1C,CELF5,ATCAY,EID2B,ZIC5,IGSF1,HES5,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,KTN1,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,ADAM22,NRBP2,TAGLN3,MXI1,LINC00672,NEXMIF,MYT1,NASP,NCAM1,NCAM2,NELL2,NOVA1,NRCAM,NTRK2,NUCB2,GPR137C,PAK3,PAX6,PCDH9,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,PPP3CC,EPDR1,MAPK10,MDGA2,ELOVL2,PXK,PTPRD,EML5,PTPRZ1,ENOX1,FEZF2,PRRT2,RFX5,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,HSPA4L,SCG5,ZFP30,KIF21A,PPP1R9A,ARX,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,DOP1A,TRERF1,SOX2,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,FAM168A,KLHL7,SYT11,FGD4,RHBDL3,SYN1,SYP,ASTN2,ATP11A,ANKRD12,SEMA4A,MCF2L,TMEM178B,ACSL6,CUX2,TCF7L2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,SLAIN1,MGAT5B,PLPPR2,CCDC136,RBFOX3,WNT7A,NPDC1,ZIC3,ZNF23,TRIM9,FMN2,LYPD6,CELF4,DPYSL5,LRP8,SHD,STMN4,TUBA1A,VPS35L,WNK2,FZD3,KLHDC1,ST8SIA2,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.34E-67 6.82E-64 7.58E-65 6.91E-64 194 335 "ASIC1,KIAA1211,KIDINS220,SYT13,CDC42BPA,ANK2,ANK3,PPFIA2,APBA2,APLP1,CADPS,ASCL1,DACT3,ATP2B1,NOL4,ADGRB3,CDK5R1,CACNA1G,GPC2,THSD7A,RUNX1T1,INA,SEPT7,DCLK1,ADGRG1,CHGB,CLCN4,NRXN1,NRXN2,CRMP1,SLC32A1,AATK,CSNK1E,NCAN,PLXNA4,RIMS2,ST18,KIAA0408,TCAF1,DCC,PITPNC1,DNAJC6,JAKMIP2,CEP170,SV2A,NTM,CPEB2,DPYSL2,DSCAM,EBF1,SEZ6L2,OPTN,EFNB3,SUGP2,KMT5B,ELAVL2,ELAVL3,ELAVL4,USPL1,EMX2,EN2,EPB41,DMTN,ANKRD13B,SPEG,NRN1,TUBB3,TAOK3,MED12L,FGF14,AMOTL2,MEX3B,AFF2,NBEA,NSG2,NSG1,PNMA2,FUT9,DOT1L,PHYHIPL,GABRA1,GAD1,GAD2,GAP43,SRRM4,DNER,NTNG2,TCERG1,DCLK2,GNAO1,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,PSIP1,CELF3,UBE2QL1,ZHX1,FRMD5,CELF5,ATCAY,SHISAL1,INSM1,TUBB2B,KCNMA1,KIF5C,KLC1,L1CAM,STMN1,LMO1,MAP4,MAP6,MARK1,MEIS2,CD200,SCG3,TAGLN3,NCAM1,NEFM,NELL1,NEUROD1,NHLH1,NKX2-2,NNAT,NOVA1,GPR137C,PAK3,PBX1,PCDH9,GNG2,FTO,SLC25A23,SCHIP1,POU3F2,PRKACB,PKIA,PRKCB,MAPK8,MDGA2,PLPPR1,PTPRD,PTPRN2,PTPRO,RALGDS,ARID4A,ZFHX4,RTN1,AMER2,CSRNP3,ATXN2,SCN2A,SCN3A,SMPD3,ASIC4,SCG5,WDR47,SHANK2,RIMS1,TMCC1,MYT1L,KIF21B,SOX11,ZBTB43,CLASP2,SEPT3,GSE1,SYT1,TAL1,CNTN2,KIAA1107,DICER1,ZFPM2,THRA,RBFOX2,DOK6,RGMB,FNDC5,TUBB2A,UCHL1,MICU3,FMN2,NDRG4,CELF4,ANKS1B,ZNF195,PRDM2,SLC38A1,STMN4,TUBA1A,PCBP4,PAK5,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.65E-67 4.92E-63 4.92E-64 4.49E-63 340 827 "SERPINA3,SLITRK1,ADCY8,ADCYAP1R1,SORCS1,RNF150,ADGRF5,PCDH10,FAM135A,SYT13,DPP10,ANK2,PPFIA2,VAT1L,SLC7A14,CADPS,ASCL1,ASPH,ASTN1,INSYN2B,ATP2B2,RNF182,NOL4,ADAM23,BACH1,ADGRB3,BCHE,NRP2,CDK5R1,DST,ARHGEF7,LDLRAD4,CACNA1B,THSD7A,PTBP2,CH25H,BRSK2,RUNX1T1,CBLN1,CDC42,CDH2,CDH10,DCLK1,LGI1,CDO1,CLGN,CRLF1,RCBTB2,CHGB,CHN2,SYNPR,RAB3C,NRXN3,CNR1,CNTN1,AKAP6,COL9A1,BTF3L4,COL9A3,MYRIP,ZNF521,FAM171B,CREM,CRMP1,HAPLN1,ANKRD44,NCOR1,ABCG1,CRYM,FEZ1,SOCS5,PHACTR3,ERC2,NRSN1,RIMS2,ST18,DOCK4,TOX,SCRN1,BRINP1,PITPNC1,DNAJC6,JAKMIP2,ZNF804A,CEP170,MAGI2,TMEM130,GSDME,SNAP91,CHRDL1,DLX1,GRIN3A,RAB39B,CALN1,DRD1,DRP2,ABCC9,GOLT1B,EBF1,EDIL3,ST8SIA3,EDN3,EDNRA,EDNRB,ATL1,EFNA3,EGFR,ABI2,ASB3,TENM1,ELAVL2,ELAVL4,RGS17,PCOLCE2,EPHA5,KCNMB2,ETV1,EYA1,CLVS1,WAC,FABP7,TMEM132C,TUBB3,EFEMP1,ST3GAL6,SPSB4,FGF13,UBE2E3,MEX3B,CAP2,FOXF2,SGIP1,C2orf88,NBEA,DACH2,PNMA2,TVP23A,PHYHIPL,MEGF11,MEGF10,GABRA1,GABRA4,CHL1,GABRB3,GAP43,SYT17,SRRM4,GART,WASF3,CPLX1,DNER,GCNT2,GFRA1,GFRA2,PCDH17,PPARGC1A,GLRB,PCDH11X,KIAA1958,RAB40B,B4GALNT4,GPR17,GPR22,RAPGEF4,STMN2,GRIA2,GRIK1,GRM3,GRM7,KIF3A,FAM19A2,GUCY1A1,GUCY1B1,MAP4K5,GYG1,WIF1,RASSF8,HAS2,UBE2QL1,FRMD3,BACH2,NEGR1,AGFG1,SHISA6,CELF5,IFI16,INSM1,LRRTM3,KCNA1,KCNK2,KCNQ2,KIF5A,KIF5C,SYTL4,MAP2,MAP4,MAPT,MARK1,IL17D,SCG3,RSPO2,MYH3,NAP1L2,NAP1L3,NCAM2,NDP,NEFM,NPTX1,NTRK2,DDR2,OPHN1,CLDN11,ZNF827,PAK3,CNTN3,PCDH8,PDE1A,PDE4B,PDE4D,PIRT,SLC10A4,GPR85,GNG2,DUSP26,NLGN3,SERPINI1,NALCN,PIK3R1,PLP1,SMIM7,HMGCLL1,TRHDE,LRP12,PRRX1,MAGEL2,EPB41L4B,LRRN3,PPP3CB,PKIA,MAPK10,DIRAS2,PRPH,GDPD1,PTHLH,PTPRO,PTPRZ1,TMEM255A,FAT4,ENOX1,SLC6A15,ZMAT4,RET,FIGN,RGS4,TTLL7,ZFHX4,C12orf49,ROBO1,ARMH4,PRR5L,RPS20,RTN1,RYR3,S100B,SALL1,CSRNP3,LRFN5,SCN3A,FAM19A1,SGK1,NTNG1,DZIP1,ANKRD6,WDR37,ZNF365,SLC1A3,SLC14A1,NAPB,CXXC4,LIMCH1,SNAP25,PDZRN3,UNC80,SCN3B,SOX2,SOX11,NPAS3,C11orf87,ZC4H2,MPRIP,ELOVL4,CEP68,TTBK2,KLHL7,SYT11,PLCB1,SYN2,SYT1,SYT4,TAC1,MTCL1,UNC5D,ADGRL3,ACSL6,TCF4,CUX2,PCDHB15,PCDHB10,PCDHB7,PCDHB3,HIF3A,HHIP,TIAM1,TIMP4,ASXL3,KAT6B,SYNPO2,TRPS1,SSBP2,TUB,TMEFF2,CADM1,RPRM,FRRS1L,SLAIN1,FLRT2,VSNL1,WIPF1,PCDH20,AGMO,FMN2,MKRN3,FSTL5,LRP8,STMN4,KCNAB1,GOPC,FAM13C,FZD3,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.30E-66 1.17E-62 1.07E-63 9.71E-63 187 319 "ASIC1,CSMD2,ADCY5,SLITRK1,SLC12A5,SMIM17,PCDH10,ANK3,PPFIA2,APBB2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,FGF17,CDK5R1,CACNA1A,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,REPS2,LONRF2,CDH8,SYNPR,KIAA1549L,NRXN1,NRXN2,CNTN1,CRMP1,ANKRD44,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,CTNND2,ST18,CCDC144A,BRINP1,DBI,ZNF804A,ZEB2,COPS7A,SPOCK3,NTM,OLIG1,DPP6,CACNG7,PLXNC1,TMEM132E,RASA4,ELAVL3,ELAVL4,EN2,OLIG2,DMTN,FABP7,TAOK3,FGF12,C1orf61,NSG2,CSPG5,NSG1,GABRA1,GABRB3,GABRG1,GABRG2,FAM184B,JPH4,GAP43,DNER,ZNF276,MAP7D2,GNG3,GPM6A,GPR17,STMN2,GRIA1,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,ACOT7,SCRG1,NEGR1,SHISA6,HSP90AA1,HTR2A,BRINP3,KCND2,KCNK2,KCNMA1,STXBP5,STMN1,C2orf80,ASPRV1,MAOB,MMP17,MT3,SCG3,NEXMIF,NCAM1,NELL1,NELL2,NNAT,CNOT4,NOVA1,KSR2,OPCML,OXTR,PCSK2,PDGFRA,GPR85,TMOD2,GDAP1L1,SERPINI1,PMP2,SCHIP1,NXPH1,PPP2R2B,LRRN3,NKAIN4,MDGA2,PLPPR1,PTN,PTPRZ1,TMEM145,RAP1GAP,ARID4A,BSDC1,RIT2,RORB,LRRK2,RTN1,RYR3,S100B,SCN2A,SCN3A,ASIC4,BCAN,SIRT2,TRIM67,LIMCH1,SNAP25,KIF13A,LMBRD1,DOP1A,MYT1L,SOX10,HECW1,SPTB,SST,SYT1,SYT5,CAMSAP2,KIAA1107,TCF4,RALYL,AP4E1,TMOD1,CSMD1,RUNDC3B,TMEFF2,VSNL1,CELF4,REEP1,FSTL5,ANKS1B,PLPPR5,CA10,STMN4,TUBA1A,SCG2,ITM2C,PAK5,JMJD1C,NETO1,SLC4A10" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.83E-64 3.48E-60 2.90E-61 2.65E-60 296 684 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,GALNT16,RNF157,ERMN,PLEKHH1,PTCHD1,MTUS1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,PPFIA2,EPB41L5,APLP1,MAGEE2,LRRC4C,SHTN1,MADD,RGS20,ASCL1,NCOA1,ASTN1,CADM3,ADAM23,CARMIL3,ADGRB3,PROM1,BMPR1B,DST,JAZF1,SGCE,CACNA1A,THSD7A,DIRAS1,HAP1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,ADGRG1,SRSF11,JAM2,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,LETMD1,SLC4A8,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,CNTNAP2,FAM169A,ERC2,PPP6R2,ST18,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ELAVL2,ELAVL3,CERCAM,ELAVL4,RGS17,BSCL2,TMEM35A,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,ADGRV1,FAM198B,FABP7,ACSL4,TUBB3,TAOK3,ATP8A1,CHST15,FHL1,FOXG1,SEMA6C,DPYSL4,KHDRBS3,FUT9,TPPP3,NRG3,PHYHIPL,ILDR2,GAD1,SRRM4,ACSS1,KIAA1841,FAXC,GFRA1,PPARGC1A,GLDC,TOX3,MAP7D2,GPM6B,DIPK1C,PCLO,CACFD1,MFSD2A,SOX21,LINGO1,FAM222A,TOX2,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,HES5,BRINP3,TUBB2B,LRRTM1,KCNH2,KCNN3,KTN1,LSAMP,LSS,MAP2,MARK1,MBP,MEIS2,MGAT3,MSI1,ADAM22,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NNAT,NRCAM,NTRK2,NUCB2,GPR137C,PAK3,PAX6,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,SLC25A23,PLXNB1,MAPKAP1,NECAB2,SLC36A4,FAT3,POU6F1,EPDR1,MAPK10,GDPD1,MDGA2,ELOVL2,PXK,PTPRD,EML5,ENOX1,GAL3ST4,PRRT2,RFX4,RFX5,TCP11L1,MEG3,RTN1,STX1B,CCDC112,MAPK12,CSRNP3,ATXN1,LRRTM4,LINC00461,ZFP30,KIF21A,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,MAST1,SORCS3,SMARCD3,MAPKBP1,TRERF1,SOX2,SP4,GLT8D1,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,FAM168A,SYT11,RHBDL3,SYN1,SYP,ASTN2,ATP11A,SEMA4A,MCF2L,TMEM178B,WWC1,WSCD1,ACSL6,CUX2,AZIN2,TMEM151B,PSD3,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,SSBP2,TUB,TUBB2A,SLAIN1,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,DPYSL5,SHD,STMN4,TUBA1A,WNK2,FZD3,ST8SIA2,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.80E-62 2.45E-58 1.88E-59 1.72E-58 182 319 "ASIC1,CSMD2,TMEM132B,SLITRK1,SLC12A5,KIDINS220,SMIM17,PCDH10,ANK1,ANK3,PPFIA2,LRRC4C,ASCL1,DNAH17,ATP2B1,NOL4,TTC9B,ADGRB1,ADGRB3,BCL7A,CDK5R1,CACNA1G,CACNA1B,CACNA1E,ZNF555,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,SYNPR,KMT2C,KIAA1549L,NRXN1,NRXN2,CRMP1,ANKRD44,CSNK1E,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,RIPOR2,HDAC4,BRINP1,ZNF804A,CEP170,SPOCK3,OLIG1,DPP6,EBF1,RASA4,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,OLIG2,DMTN,EPHA5,CEP85L,NRN1,FABP7,TUBB3,TAOK3,KIAA1109,FGF12,C1orf61,NSG2,NSG1,OGA,GABRA1,GABRG1,GABRG2,JPH4,GAP43,DNER,NTNG2,RAB30,TNRC6A,MAP7D2,GNG3,GPM6A,B4GALNT4,STMN2,GRIA2,GRIA4,GRIK2,GRM5,KIF3A,FAM19A2,PTPN5,TOX2,NEGR1,SHISA6,HSP90AA1,BRINP3,KCND2,CREG2,KIF5C,L1CAM,STMN1,LSAMP,MOBP,NEXMIF,NAP1L2,NCAM1,NELL1,NELL2,NNAT,NOVA1,NTRK2,KSR2,OPCML,OXTR,PBX1,PDGFRA,TMOD2,SERPINI1,PIK3R1,NXPH1,LRRN3,PRKACB,PLPPR1,RASGRF1,ZYG11B,REV3L,RIT2,SLC25A36,RORB,RTN1,AMER2,ATXN2,SCN2A,SCN3A,ASIC4,SLC8A3,TRIM67,SHANK2,SLC22A4,LIMCH1,SNAP25,USP33,MYT1L,KIF21B,SOX11,SST,ABCC8,SYT1,SYT5,KIAA1107,RALYL,ARHGEF12,SIK3,RIMBP2,CSMD1,RUNDC3B,TMEFF2,VSNL1,CELF4,REEP1,FSTL5,ANKS1B,ZFAND5,CA10,CADM2,SLC38A1,STMN4,PRDM8,TUBA1A,SCG2,KCNAB1,DNAH10,RTN4,PAK5,SLC4A10" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.09E-61 5.54E-58 3.96E-59 3.61E-58 337 849 "KCNH8,ASPHD1,SYN3,ACHE,GPRIN1,CSMD3,NDRG2,ADCYAP1R1,ADD2,PNMA8B,SORCS1,KLHL13,DISP3,PCDH10,UNC79,ANK2,C6orf89,PPFIA2,CNIH2,APBA2,APBB1,APLP1,VAT1L,LGR5,SLC7A14,ARHGDIG,CADPS,ASCL1,ASTN1,ATP1A3,CADM3,KIF1A,ADAM23,TTC9B,ADGRB3,SEC11C,BCHE,NRP2,CACNA1B,CACNA1E,CACNA2D1,HAP1,MAP7,CCK,INA,CD38,LONRF2,CDH10,DCLK1,LGI1,CBARP,CHGA,CHGB,CHN1,RAB3C,CHRNB2,RAB33A,NRXN1,CLTB,SULT4A1,CNR1,PICK1,CNTFR,CNTN1,PCYT1B,CNRIP1,SLC35F1,FAM171B,AKAP12,CRMP1,CLIP3,FEZ1,PHACTR3,PLXNA4,SDC3,ERC2,CMTM5,NRSN1,RIMS2,ST18,KIAA0408,HDAC9,DGKB,SCRN1,DNAJC6,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SV2A,SRGAP3,KBTBD11,DLG2,RAB39B,SLC29A4,CPEB2,FAM78B,EBF1,EDIL3,ST8SIA3,SEZ6L2,EDNRB,ATL1,FRY,CACNG7,CELSR3,ELAVL2,ELAVL3,ELAVL4,BSCL2,RCAN2,KCNMB2,NCALD,APC2,RRAGB,CEND1,EYA1,REEP2,CLVS1,FABP7,CACNG3,TUBA1B,TUBB3,TUBB4A,CORO2B,FDFT1,OLFM1,FGF13,ACTL6B,MAD2L2,SGIP1,AFF2,NELFCD,DCTN2,DPYSL4,TMEM107,NSG2,NSG1,TPPP3,TVP23A,PHYHIPL,GABRB3,FAM184B,GAP43,MTHFD2,SYT17,SRRM4,CPLX1,IGSF5,FAXC,GFRA1,GFRA2,C1QL1,RUNDC3A,MAP7D2,PCSK1N,KCNMB4,DCLK2,GNAO1,GNG3,GP1BB,TDRKH,B4GALNT4,GPR17,GPR22,PCLO,TUBA1C,STMN2,GRIA2,GRIA4,GRIK2,GRIK3,GSTM5,FAM222A,CELF3,UBE2QL1,ARHGAP36,HLF,ACOT7,SCRG1,HSPA1L,ATCAY,DISP2,LIX1,INSM1,TUBB2B,KCNA4,KCNN2,KCNN3,KIF5A,KIF5C,KLC1,L1CAM,LMO1,SYTL4,LSAMP,PACRG,MAOB,MAP2,MAP6,MAPT,MARK1,MMP16,MSI1,ADAM22,SCG3,TAGLN3,DDX25,MYT1,NAP1L2,NCAM1,NCAM2,NEFM,NEFH,NELL2,ALDH1L2,NNAT,NPY,NOVA1,PCBP3,NRCAM,NTRK3,KSR2,PCDH9,SLC10A4,GNG2,PENK,TMOD2,CYTL1,PFKP,NLGN3,GDAP1L1,SERPINE2,NALCN,FXYD1,PLP1,PMP22,POLR2F,FSD1,PPP1R1A,PPP2R2B,LRRN3,PKIA,PRKCB,MAPK10,PROX1,PRPH,NDUFS7,ELOVL2,STK32A,EML5,PTPRN,PTPRZ1,RAB3A,RALGDS,RADX,SLC6A15,CRTAC1,ZMAT4,RET,RGS4,RGS7,PRIMA1,RIT2,NUDT11,ARMH4,PLPPR3,SOX8,RTN1,RYR3,S100B,SATB1,CSRNP3,SCN2A,SCN3A,FAM19A1,SMPD3,HSPA4L,SCG5,KIF21A,SH3GL3,CNKSR2,CCDC92,CXXC4,MAST1,SNAP25,SNCA,SNRPN,UNC80,SCN3B,SOX2,TNIK,SOX10,HECW1,NFASC,SST,EPB41L3,NACAD,ELOVL4,SEPT3,STXBP1,GSE1,SYT11,NUDT10,SYN1,SYN2,SYP,SYT1,SYT4,ASTN2,CUX2,FBXL16,TNR,CHST5,RUNDC3B,SSBP2,TUBB2A,TMEFF2,CADM1,UCHL1,SLAIN1,MTCH1,RBFOX3,NPDC1,ZNF32,KCNT2,ATP6V0E2,MKRN3,FSTL5,DPYSL5,PARP6,STMN4,TUBA1A,SCG2,PCBP4,MVB12B,AP3B2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.02E-60 2.05E-56 1.37E-57 1.24E-56 326 818 "CSMD3,SLITRK1,RNF157,SORCS1,USP31,TAOK1,PCDH10,FAM135A,OGT,DPP10,ANK2,APAF1,APC,PHYHD1,VAT1L,SHTN1,SLC7A14,TMEM263,CADPS,ASCL1,ASPH,ASTN1,SLC4A4,ATP2B1,RNF182,NOL4,ADAM23,ADGRB3,BARD1,BCHE,NRP2,ARHGEF7,LDLRAD4,CACNA1B,CACNA2D1,PTBP2,CANX,VSTM2A,BRSK2,RUNX1T1,INA,CDC42,CDH2,CDH10,DCLK1,LGI1,CFL2,SRSF11,CHGB,SOCS6,SYNPR,RAB3C,NRXN3,CLCN3,CNR1,CNTN1,AKAP6,MYRIP,SLC35F1,FAM171B,CRMP1,HAPLN1,VCAN,DZIP3,ERC2,APPL1,PLCXD3,CTNND2,NRSN1,RIMS2,ST18,HDAC9,TOX,KIF26A,TM9SF4,DGKB,SCRN1,DNAJC6,JAKMIP2,ZNF804A,MYEF2,MFAP3L,CEP170,TMEM130,SNAP91,ARNT2,KBTBD11,GRIN3A,CALN1,CPEB2,PDCD6IP,DYRK1A,EBF1,EDIL3,ST8SIA3,EDNRA,EDNRB,HIPK3,TENM1,ELAVL2,ELAVL3,ELAVL4,CALCRL,EPHA5,ETV1,EYA1,FABP7,TMEM132C,TUBB3,EFEMP1,DLC1,ATP8A1,KIAA1109,FGF13,SUCO,UBE2E3,CAP2,FOXF2,SGIP1,SMC2,PDLIM5,NSG2,CELF1,DACH2,OGA,DKK3,MEGF10,GABRA1,GABRA3,CHL1,GABRB1,GABRB3,AHCYL1,IQGAP2,GAP43,SYT17,DNER,GFRA1,GFRA2,PCDH17,GHR,GLRB,PCDH11X,RAB40B,GPR22,RAPGEF4,STMN2,GRIA1,GRIA2,GRM3,GRM7,FAM19A2,MAP4K5,WIF1,RASSF8,KLF12,BACH2,ZDHHC15,NEGR1,CELF5,MSL1,IFI16,RBPJ,DISP2,IL6ST,INSM1,LRRTM3,KCNC2,KCND2,KCNK2,KCNMA1,KCNQ2,KIF5A,KIF5C,LIFR,SYTL4,HECTD2,SMAD1,MAOB,MAP2,MAP4,MAPT,MARK1,CHIC1,KITLG,MKLN1,MMP16,SAMD5,MSI1,SCG3,RSPO2,MYH3,MYO5A,NAP1L2,NAP1L3,NCAM2,NDP,NEFM,NEK1,NFIA,ALDH1L2,NNAT,NOVA1,NRCAM,NTRK2,CLDN11,PAK3,CNTN3,PDE3A,SLC10A4,GPR85,GNG2,TMOD2,DUSP26,NLGN3,SERPINI1,NALCN,PIK3C2A,PIK3R1,PCDH18,HMGCLL1,TRHDE,PRRX1,FAT3,KANSL1,MAPK8,MAPK10,DIRAS2,PRPH,ZIK1,EML5,PTPRG,PTPRO,FAT4,RBBP6,GAL3ST4,SLC6A15,RET,REV3L,RGS4,KLHL11,NUDT11,ZFHX4,SETD5,ROBO1,RPE,RTN1,RYR3,SALL1,CSRNP3,SCN3A,LRRTM4,FAM19A1,TRA2B,SCG5,KIF21A,NTNG1,ST8SIA1,DZIP1,ANKRD6,RUFY2,SLC12A2,NAPB,SLC15A2,CXXC4,SNAP25,SCN3B,SOX2,SOX5,SOX11,ZHX3,MYCBP2,PEG10,KIF1B,NPAS3,C11orf87,CLASP2,EPB41L3,LARP4,ELOVL4,KLHL7,SYT11,FGD4,PRRC2C,PLCB1,SYN2,SYT1,SYT4,PJA1,CAMSAP2,ADGRL3,AGTPBP1,FBXW11,TBL1X,CUX2,TRIM2,CLASP1,PCDHB7,PCDHB3,NSD1,HHIP,ASXL3,ZFP91,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRPS1,SSBP2,TTC3,TMEFF2,CADM1,RPRM,UBE3A,VLDLR,WRN,MKRN3,CELF4,FSTL5,LRP8,STMN4,LMAN2L,FAM13C,MSRB3,NETO1,SOCS4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 5.30E-60 2.71E-56 1.69E-57 1.54E-56 306 744 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,CNIH2,APLP1,MAGEE2,VAT1L,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CADM3,ATP6V1G2,ADAM23,CARMIL3,ADGRB3,DST,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,HAP1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,ADGRG1,FOXN3,JAM2,SLIT2,KMT2C,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,COL4A5,SLC25A27,SLC4A8,MFSD4A,SLC35F1,FAM171B,CREB5,CLIP3,AATK,CSF2RA,FEZ1,PDE4DIP,CNTNAP2,SLITRK5,ERC2,CTNND2,PPP6R2,ST18,RUBCN,PYGO1,HDAC9,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,NTM,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,EDNRB,CACNG7,ING4,ELAVL3,CERCAM,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,ADGRV1,FAM198B,FABP7,TUBB3,TUBB4A,TAOK3,ATP8A1,CHST15,FGFR1,FOXG1,DPYSL4,NBEA,NSG2,FUT9,NRG3,ZMAT1,SRRM4,ACSS1,FAXC,GFRA1,CSDC2,PPARGC1A,GLDC,MAP7D2,GPM6B,DIPK1C,TDRKH,PCLO,CACFD1,MFSD2A,LINGO1,CELF3,TOX2,FRMD5,KLF12,AGBL5,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,CREG2,LRRC4B,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,NRBP2,TAGLN3,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NEFM,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PAX6,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU3F4,POU6F1,TATDN3,PPP3CC,EPDR1,MAPK10,MDGA2,PXK,PTPRD,ENOX1,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,SNAP25,MAPKBP1,TRERF1,SOX2,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,MAPK8IP3,ZSCAN29,DIP2A,SEPT3,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,WSCD1,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,UCHL1,SLAIN1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZIC1,ZNF708,ZNF23,TRIM9,FMN2,LYPD6,CELF4,TMEM237,DPYSL5,SHD,STMN4,TUBA1A,VPS35L,WNK2,KLHDC1,PIANP,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 9.05E-60 4.62E-56 2.72E-57 2.48E-56 264 594 "ADARB2,KLHL32,TMEM132B,TMCC3,SLC12A5,KIDINS220,AP2A2,GPR158,KLHL13,PCDH10,SYT13,BEGAIN,CDC42BPA,ANK2,ANK3,PPFIA2,APLP1,AMER3,APP,SHTN1,CADPS,MARK4,ZBTB10,B3GALT2,NOL4,CDK5R1,SCAPER,GPC2,LDLRAD4,CACNA1E,KALRN,CARS,RUNX1T1,INA,SEPT7,LONRF2,DCLK1,ADGRG1,CHGA,CHGB,NRXN1,NRXN2,DNAJB5,CNTN1,BTF3L4,IFFO1,PREPL,CREM,CRHBP,AKAP12,CRMP1,RGS6,IPCEF1,NCAN,PLXNA4,SLITRK5,SDC3,ERC2,RIMS2,RUBCN,KIAA0408,RIMS3,DAPK1,AIF1L,DCC,PITPNC1,DNAJC6,MYEF2,CEP170,SNAP91,SV2B,NTM,ARNT2,DNM1,DPP6,FAM135B,OPTN,KMT5B,PLXNC1,EIF4G2,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EN2,RCAN2,EPHA5,ERBB4,FABP7,TUBB3,TAOK3,KAT8,FGF13,IP6K2,NBEA,PDLIM5,NPTN,NSG2,CELF1,NSG1,PNMA2,FUT9,AP4B1,BRSK1,PHYHIPL,DKK3,GABRB3,TRAF3IP2,JPH4,GAP43,SRRM4,DNER,FAXC,GFRA1,COPS8,TOX3,HTATSF1,OS9,GNAO1,GNG3,PRRC2B,GPM6A,GPR22,STMN2,GRB10,GRIA2,GRM5,IL1RAPL1,CELF3,TOX2,SCRG1,NEGR1,SHISA6,CELF5,SHISAL1,C5orf24,INSM1,KIF5C,KLC1,L1CAM,LSAMP,MAP6,MARK1,CD200,PTOV1,TAGLN3,TCEAL5,BEX5,NAP1L2,NAP1L3,NCAM1,NEFM,NNAT,IGSF11,CHAMP1,ZDHHC22,PBX1,PCSK2,ENPP2,SLC10A4,GPR173,GNG2,TMOD2,OLA1,CDK14,RETREG1,SLC25A23,PDZRN4,LRP12,FAT3,POU3F2,POU6F1,LRRN3,PRKACB,PKIA,MAPK8,PTPRD,PTPRN2,PTPRO,PTPRZ1,ZNF793,RALGDS,ARID4A,REV3L,PRRT2,GTDC1,ZFHX4,ROBO1,ROBO2,KIAA0895L,WLS,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SMPD3,SOX6,ASRGL1,SCG5,SH3GL3,CPEB3,FBXO11,CLSTN1,WDR47,RUFY2,CCDC88A,SHANK2,NAPB,TET1,CPEB4,SNCA,SCN3B,MYT1L,KIF21B,SOX11,ZHX3,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SRPK2,CLASP2,SEPT3,SYT1,SYT4,TAC1,TACC1,TMEM178B,KIAA1107,EHBP1,PSD3,AKNA,ENHO,CSMD1,RBFOX2,SEZ6L,DOK6,RUNDC3B,RUSC1,TTC3,TUB,TUBB2A,TMEFF2,CADM1,UCHL1,RICTOR,ZNF17,CELF4,REEP1,DPYSL5,ANKS1B,LRP8,STMN4,TUBA1A,MVB12B,PAK5,CERS6,RNF170,PIANP,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.32E-59 6.75E-56 3.75E-57 3.42E-56 369 988 "CPNE2,TTYH1,NCKAP5,FMNL2,KLHL32,SLITRK1,PLEKHH1,PTCHD1,KIAA1324,WDR35,DISP3,TAOK1,C1QTNF1,CEP126,FGD2,EPB41L5,APLP1,MAGEE2,PHYHD1,SHTN1,ASCL1,PDE8B,NCOA1,ASTN1,ATM,ATP1A3,ATP2B2,KIF1A,ADAM23,CARMIL3,ADGRB3,BCHE,FGF17,PROM1,JAZF1,LDLRAD4,CACNA1A,CACNA2D1,DIRAS1,HAP1,PTBP2,CAMK2A,VSTM2A,CBLN1,INA,C1orf52,CDK11B,LRBA,CDC25B,CDH2,MAGI1,ADGRG1,SRSF11,CBARP,FOXN3,JAM2,SLIT2,LHX2,NRXN3,CLCN3,KIAA1549L,NRXN2,CLTB,TJP2,DNAJB5,QKI,NIPBL,IGLON5,ARHGEF6,IQCK,WHRN,COL4A5,COL9A2,SLC4A7,SLC4A8,ACBD5,IGDCC3,NECTIN3,SLC35F1,FAM171B,CRMP1,AATK,CSF2RA,LRRC3B,NCAN,CNTNAP2,SLITRK5,ERC2,CTNND2,RIMS2,ST18,KATNAL2,PHF19,KIAA0586,SCRN1,DCC,JAKMIP2,C8orf34,MYEF2,FBXO25,DDX46,SRGAP3,G3BP2,KBTBD11,DLX1,RAB39B,DMD,CASP8AP2,DRP2,DTNA,MAMLD1,ABCC9,ST8SIA3,TMTC1,FSD1L,EFNA3,PLXNC1,ELAVL2,ELAVL3,ELAVL4,RGS17,TMEM35A,EMX2,OLIG2,ENO2,EPB41,LRRC23,EPHB1,SLC43A2,APC2,RRAGB,ADGRV1,REEP2,CLVS1,NSRP1,FABP7,ZIC4,TUBB3,TUBB4A,CEP78,SPSB4,FGF12,FGFR3,FOXG1,SEMA6C,AFF2,ZNF605,DLL3,STAU2,FUT9,B3GAT1,PHYHIPL,ZMAT1,ILDR2,GAD1,TMEM8B,SRRM4,ACSS1,KIAA1841,CSDC2,PPARGC1A,RUNDC3A,NTNG2,GLDC,TOX3,PCDH11X,MAP7D2,DCLK2,GNG3,GNG4,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,CIT,RNF165,MFSD2A,SOX21,RNFT2,CELF3,TOX2,FRMD5,DDX19B,KLF12,BACH2,IGFBPL1,USP51,CELF5,ATCAY,SHISAL1,ZIC5,LRRCC1,IGSF1,HES5,BRINP3,TUBB2B,KCNH2,KCNN3,CREG2,KIF5C,KTN1,L1CAM,GPR155,MAP2,IL17D,TM6SF1,SHC3,MEIS1,KITLG,PPM1L,CPNE9,MSI1,ADAM22,MSR1,SCG3,TAGLN3,LINC00672,MYT1,NASP,NEFM,NELL2,NNAT,NOVA1,NPR2,SLC11A2,NRCAM,NTRK2,ODF2,GPR137C,PAK3,PRTG,PDE4D,PGAM2,NLGN3,SERPINE2,SEMA5B,GPSM2,SLC25A23,PLXNB1,TRHDE,PRRX1,SDK2,MAGEL2,SPATA6,EPB41L4B,FAT3,NKAIN4,MAPK10,DIRAS2,PROX1,GDPD1,RELN,MDGA2,CNTLN,ELOVL2,PTPN13,PTPRD,EML5,CCDC40,RAD51D,IQSEC3,FAM184A,ZNF493,ARID4A,FEZF2,BEND5,GAL3ST4,PRRT2,RFX4,GSTCD,TMEM206,MRAP2,BAALC,SGSM1,ADAL,STK32B,MEG3,RTKN,CLIP1,RTN1,CCDC112,SALL1,MAPK12,CSRNP3,LRRTM4,LINC00461,SOX6,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,ARX,FBXO11,FHOD3,CCDC92,SLC1A2,SLC1A3,FAM214B,PKNOX2,CXXC4,MAST1,SNAP25,SNRPN,TMCC1,PDZRN3,SOX2,SOX5,SOX11,LHFPL4,KIF1B,NPAS3,CLSTN2,DIP2A,GSE1,ACSBG1,SYT11,FGD4,SYNE2,RHBDL3,SYN1,SYP,ASTN2,TACC1,SEMA4A,TMEM178B,WWC1,WSCD1,ACSL6,SATB2,CUX2,TCF7L2,TRIM2,WASHC4,PSD3,FRYL,AHCYL2,CCDC173,THRA,TJP1,NR2E1,PIK3R5,SYNPO2,PRMT8,TRPS1,CA14,TUB,SLAIN1,MGAT5B,ZIC1,ZIC2,ZIC3,FMN2,LYPD6,ZBTB16,REEP1,DPYSL5,SLC38A1,STMN4,STOX2,GAL3ST3,WNK2,FZD3,ST8SIA2,SPATA13,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.82E-59 1.44E-55 7.57E-57 6.90E-56 218 441 "ASPHD1,ACHE,CSMD3,ADCYAP1R1,SORCS1,PCDH10,UNC79,ANK2,PPFIA2,APBA2,APBB1,APLP1,VAT1L,LGR5,SLC7A14,ARHGDIG,CADPS,ASCL1,ATP1A3,KIF1A,ADAM23,TTC9B,ADGRB3,BCHE,NRP2,CCK,INA,LONRF2,DCLK1,LGI1,CHGA,CHGB,CHN1,RAB3C,RAB33A,NRXN1,CLTB,PICK1,CNTFR,CNRIP1,SLC35F1,FAM171B,CRMP1,CLIP3,FEZ1,PLXNA4,ERC2,NRSN1,RIMS2,ST18,KIAA0408,HDAC9,SCRN1,JAKMIP2,ZNF804A,SNAP91,SPOCK3,KBTBD11,DLG2,RAB39B,SLC29A4,FAM78B,EBF1,ST8SIA3,SEZ6L2,EDNRB,ATL1,FRY,CACNG7,ELAVL2,ELAVL4,BSCL2,KCNMB2,CEND1,EYA1,CLVS1,FABP7,CACNG3,TUBB3,TUBB4A,CORO2B,FDFT1,FGF13,SGIP1,NELFCD,TMEM107,NSG2,NSG1,TPPP3,PHYHIPL,GABRB3,GAP43,SYT17,SRRM4,IGSF5,GFRA1,GFRA2,C1QL1,RUNDC3A,MAP7D2,PCSK1N,KCNMB4,DCLK2,GNAO1,GNG3,GP1BB,TDRKH,B4GALNT4,GPR17,PCLO,STMN2,GRIA2,GRIA4,GRIK2,CELF3,ARHGAP36,ACOT7,SCRG1,DISP2,LIX1,TUBB2B,KCNN2,KIF5A,KIF5C,KLC1,L1CAM,LMO1,SYTL4,LSAMP,PACRG,MAP2,MAP6,SCG3,TAGLN3,DDX25,MYT1,NAP1L2,NCAM1,NCAM2,NEFM,NELL2,NNAT,NPY,NOVA1,PCBP3,NRCAM,NTRK3,PCDH9,SLC10A4,GNG2,PENK,TMOD2,CYTL1,NLGN3,GDAP1L1,SERPINE2,NALCN,FXYD1,PLP1,PMP22,POLR2F,PPP1R1A,PPP2R2B,PKIA,MAPK10,PROX1,PRPH,ELOVL2,STK32A,EML5,PTPRZ1,RADX,CRTAC1,ZMAT4,RET,RGS4,RGS7,RIT2,RTN1,S100B,SCN2A,SCN3A,FAM19A1,SCG5,KIF21A,SH3GL3,CNKSR2,SNAP25,SNCA,SNRPN,SCN3B,SOX10,NFASC,SST,EPB41L3,SEPT3,STXBP1,GSE1,SYT11,NUDT10,SYN1,SYP,SYT1,ASTN2,CUX2,TNR,SSBP2,TMEFF2,CADM1,UCHL1,NPDC1,KCNT2,MKRN3,FSTL5,DPYSL5,STMN4,SCG2,MVB12B" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.35E-59 3.24E-55 1.62E-56 1.48E-55 327 830 "ASIC2,ACHE,CSMD3,NDRG3,NDRG2,RNF157,ADCYAP1R1,ADD2,PNMA8B,AP2A2,NME5,PCDH10,UNC79,BIN1,ANK2,C6orf89,PPFIA2,APBA2,APBB1,APBB2,APLP1,VAT1L,LGR5,SLC7A14,ARHGDIG,CADPS,ASCL1,ASTN1,ATP1A3,CADM3,ATP6V0A1,KIF1A,TTC9B,ADGRB3,BCHE,NRP2,JAZF1,CACNA1B,HAP1,VSTM2A,CBLN1,CCK,INA,LONRF2,CDH2,DCLK1,CBARP,CHGA,CHGB,RAB3C,CHRNB2,RAB33A,CLCN3,NRXN1,CLTB,SULT4A1,PICK1,CNTFR,SLC35F1,FAM171B,AKAP12,CRMP1,CLIP3,FEZ1,PLXNA4,SDC3,ERC2,CMTM5,NRSN1,RIMS2,ST18,KIAA0408,HDAC9,SCRN1,DNAJC6,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SV2A,SRGAP3,DLG2,RAB39B,DPP6,FAM78B,EBF1,ST8SIA3,SEZ6L2,EDNRB,ATL1,EEF1A2,FRY,CELSR3,ELAVL2,ELAVL4,BSCL2,KCNMB2,DENND4A,NCALD,APC2,CEND1,EYA1,NRN1,REEP2,CLVS1,FABP7,CACNG3,TUBA1B,TUBB3,TUBB4A,CORO2B,CHST15,FDFT1,OLFM1,FGF13,SGIP1,NELFCD,COQ5,DPYSL4,NSG2,NSG1,TPPP3,BRSK1,PHYHIPL,GABRB3,GAP43,SYT17,SRRM4,CPLX1,IGSF5,FAXC,GCNT2,GFRA1,GFRA2,C1QL1,RUNDC3A,GLRB,PCSK1N,GNAO1,GNG3,GP1BB,GPM6B,TDRKH,B4GALNT4,GPR17,GPR19,GPR22,PCLO,TUBA1C,RAPGEF4,STMN2,GRIA2,GRIA4,FAM19A2,GSTM5,CELF3,IGSF21,ARHGAP19,ARHGAP36,HLF,ACOT7,HMGCR,ATCAY,DISP2,LIX1,INSM1,TUBB2B,KCNA4,KCNJ3,KCNN2,KIF5A,KIF5C,KLC1,STXBP5,L1CAM,LMO1,SYTL4,LSAMP,LSS,PACRG,MAOB,MAP2,MAP6,MAPT,MEIS1,SCG3,TAGLN3,DDX25,MYT1,NAP1L2,NAP1L3,NCAM1,NCAM2,NEFM,NEFH,NEK1,NELL2,NNAT,NPY,NOVA1,PCBP3,NRCAM,NTRK3,KSR2,PALM,PCDH9,PDE3A,SLC10A4,PENK,TMOD2,PFKP,GDAP1L1,SERPINE2,NALCN,FAM216A,FXYD1,PLP1,PMP22,POLR2F,MINDY2,PPP1R1A,PPP2R2B,PTPA,RASGEF1B,PKIA,PRKAR1B,EPDR1,MAPK10,PROX1,PRPH,SNRK,MDGA2,PSMD13,ELOVL2,STK32A,ZIK1,EML5,PTPRO,PTPRZ1,RAB3A,RALGDS,RADX,CRTAC1,ZMAT4,RET,RGS4,RGS7,RIT2,NUDT11,RNASEL,RTN1,STX1B,S100B,SATB1,SCN2A,SCN3A,FAM19A1,ZNF821,ASRGL1,MRAS,SCG5,KIF21A,FHOD3,CNKSR2,CCDC92,TRIM67,CXXC4,MAST1,SNAP25,SNCA,SNRPN,SCN3B,SOX10,BEX1,KIF1B,NFASC,CLASP2,SST,EPB41L3,ZC4H2,NACAD,ELOVL4,STX1A,SEPT3,STXBP1,GSE1,FAM168A,SYT11,NUDT10,SYN1,SYP,SYT1,SYT4,ASTN2,CAMTA1,AGTPBP1,KIAA0930,CUX2,USP22,PCDHB9,CHST8,THRA,BEX4,TNR,RUNDC3B,STXBP4,SSBP2,TUB,TUBB2A,TMEFF2,CADM1,UCHL1,SLAIN1,MTCH1,NPDC1,ATP6V0E2,FSTL5,DPYSL5,MEIS3,SLC38A1,STMN4,TUBA1A,SCG2,PCBP4,MVB12B,MARCH8,AP3B2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.07E-58 5.45E-55 2.60E-56 2.37E-55 188 349 "ABR,RBM10,FMNL2,KIDINS220,CEP126,PCDH10,DOC2A,ANK2,ANK3,SMIM29,PPFIA2,TNRC6C,TMEM108,ATP2B1,CDK5R1,SCAPER,CACNA1A,CACNA1B,CACNA1E,CAMK2B,BRSK2,RUNX1T1,FMNL3,INA,NEURL1,CDH8,DCLK1,ARHGAP33,NRXN1,NRXN2,PREPL,CRMP1,TENM4,VCAN,NCAN,PDE4DIP,ERC2,RIMS2,PYGO1,KIAA0408,GPRASP1,SCRN1,BRINP1,DCC,CEP170,TMEM130,LYPD1,SNAP91,NTM,ARNT2,KBTBD11,DYNC1I1,DPP6,EDIL3,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EPB41L1,EPHB1,STX2,TUBB3,TAOK3,NBEA,SORBS1,NSG2,NSG1,BRSK1,OGA,GABRB1,GABRB3,GAD1,JPH4,GAP43,ATP8A2,SRRM4,DNER,PCDH17,TOX3,GNAO1,PRRC2B,GPM6A,B4GALNT4,PCLO,CNTRL,STMN2,GRIA2,C1QL4,GRM5,KIF3A,RNF165,NEGR1,CELF5,ATCAY,LRRTM3,CDH20,KCND2,CREG2,KIF5C,KPNA5,L1CAM,LSAMP,ZFYVE27,MAP6,CHIC1,MEIS2,CD200,JAKMIP3,NEXMIF,NAP1L3,NCAM1,NELL1,NKX2-2,NNAT,NOVA1,OPCML,PCDH9,PDPK1,GNG2,TMOD2,RETREG1,PDZRN4,LRRN3,PKIA,PRKCB,EML5,PTPRN2,ARID4A,BSDC1,REV3L,ZFHX4,ROBO1,ROBO2,RTN1,ZNF568,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,CASC3,KIF21A,SLC1A2,SLC6A7,SLC8A1,CCDC88A,SHANK2,CPEB4,SMARCC2,MAPKBP1,SCN3B,MYT1L,KIF21B,SOX11,MYCBP2,ERC1,NPAS3,SEPT3,STXBP1,SYP,SYT1,TAC1,ANKRD12,CAMTA1,CAMSAP2,KIAA1107,AGTPBP1,CLASP1,SYNE1,ARHGEF12,PUM2,ZFPM2,KCTD2,RBFOX2,CADM1,UBTF,UCHL1,CELF4,REEP1,STMN4,TMEM178A,RTN4,PAK5,CERS6,NETO2,SLC4A10,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.54E-58 1.30E-54 5.89E-56 5.37E-55 195 372 "ACADM,ASIC1,ACLY,ABHD6,FMNL2,TMEM132B,TMCC3,KIDINS220,OSBPL8,ALCAM,SYT13,ANK2,ANK3,APBB1,APP,CPNE5,ARHGAP5,CADPS,ZSCAN18,B3GALT2,KIF1A,SEC11C,BAIAP3,FOXK1,CALB1,RUNX1T1,LDB2,INA,SEPT7,LONRF2,CDC42,CDH10,MAGI1,CFL2,CHGB,NRXN1,COG1,TMEM59L,MAP4K4,CNTN1,AKAP6,CRMP1,PLXNA4,SDC3,CALY,KIAA0408,DAPK3,DCC,PITPNC1,DNAJC6,JAKMIP2,TMEM130,SNAP91,SV2A,KBTBD11,GRIN3A,DNM1,SEZ6L2,EFNB3,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,STARD3NL,EPB41L1,RCAN2,DMTN,EPHA5,RTN3,CACNG2,FGF13,HPCAL4,EVL,NSG2,NSG1,PNMA2,FYN,DKK3,GABRB3,JPH4,GAP43,DNER,PCDH17,BRD8,MAP7D2,GNAL,GNAO1,GNG3,GPT2,GPM6A,PCLO,STMN2,RAPGEF1,GRIA2,ATE1,KIF3A,AP4S1,RABL2A,CELF3,ACOT7,NEGR1,CELF5,ATCAY,ZNF546,TUBB2B,LRRTM3,KCNN3,KIF5C,KLC1,MSANTD3-TMEFF1,LSAMP,MARK1,KITLG,AFDN,SCG3,MYO5A,BEX5,FXYD6,NCAM1,NRCAM,NRDC,KSR2,PAK3,PBX1,PCSK1,PDE4D,GNG2,TMOD2,SERPINI1,SNX10,FAT3,PPP2R2B,PKIA,PTPRN,SUSD4,ARID4A,REV3L,ZFHX4,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,SH3GL2,NLGN1,ABLIM3,SLC1A2,WDR47,SLC6A1,NAPB,CPEB4,SNAP25,SNCA,FAM126B,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,ZBTB43,LMO3,SRPK2,CLASP2,SEPT3,STXBP1,NECAB1,SYP,SYT1,SYT4,KIAA0930,PCDHA7,AHCYL2,ATP13A2,RBFOX2,TUBB2A,TMEFF2,CADM1,UCHL1,DNAJC12,VGF,VLDLR,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,SH3GLB2,RGMA,STMN4,SCG2,RTN4,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.16E-57 5.93E-54 2.58E-55 2.35E-54 303 748 "DPF1,TTYH1,ABAT,SYN3,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,CNIH2,APLP1,MAGEE2,LRRC4C,TNRC6C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CADM3,ATP6V1G2,ADAM23,CARMIL3,ADGRB3,DST,JAZF1,SGCE,CACNA1A,DDR1,CACNB2,THSD7A,DIRAS1,HAP1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,FOXN3,JAM2,SLIT2,KMT2C,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,CNTFR,IQCK,WHRN,SLC25A27,SLC4A8,ZNF521,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,LRRC3B,PDE4DIP,CNTNAP2,ERC2,PPP6R2,ST18,RUBCN,HDAC9,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ING4,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,MED12L,FGFR1,FOXG1,SEMA6C,DPYSL4,SPECC1,FUT9,NRG3,SRRM4,ACSS1,FAXC,GFRA1,CSDC2,PPARGC1A,LOXL3,GPM6B,DIPK1C,PCLO,GRIK2,CACFD1,MFSD2A,LINGO1,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,CDH20,KCNH2,KCNN3,L1CAM,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PAX6,PCDH9,PGAM2,NLGN3,GDAP1L1,SEMA5B,ZFYVE21,TMEM38A,GPSM2,SMOX,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,PPP3CA,PPP3CC,NKAIN4,EPDR1,MAPK10,SNRK,MDGA2,PXK,PTPRD,PTPRZ1,ENOX1,GAL3ST4,PRRT2,RFX5,TMEM206,KIAA0895L,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,LINC00461,SCG5,ZFP30,PPP1R9A,NTNG1,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,GKAP1,MAST1,SORCS3,SMARCD3,RCOR3,SNAP25,MAPKBP1,TRERF1,SOX2,SOX5,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,UCHL1,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,CA10,SHD,STMN4,TUBA1A,VPS35L,WNK2,PIANP,ST8SIA2,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.24E-57 6.34E-54 2.64E-55 2.41E-54 163 279 "CSMD3,ADD2,PNMA8B,PCDH10,UNC79,ANK2,PPFIA2,APBA2,APBB2,VAT1L,CADPS,ADGRB3,BCHE,NRP2,JAZF1,HAP1,INA,LONRF2,CDH2,RAB3C,CLCN3,NRXN1,FAM171B,AKAP12,CRMP1,PLXNA4,ERC2,NRSN1,RIMS2,ST18,KIAA0408,HDAC9,SCRN1,DNAJC6,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SV2A,SRGAP3,DLG2,RAB39B,FAM78B,EBF1,ST8SIA3,EDNRB,FRY,CELSR3,ELAVL2,ELAVL4,KCNMB2,DENND4A,NCALD,EYA1,NRN1,CLVS1,FABP7,TUBB3,CHST15,OLFM1,FGF13,SGIP1,PHYHIPL,GABRB3,GAP43,SRRM4,CPLX1,IGSF5,FAXC,GCNT2,GFRA1,GLRB,GNAO1,TDRKH,GPR22,PCLO,RAPGEF4,STMN2,GRIA2,GRIA4,FAM19A2,ARHGAP36,HLF,LIX1,KCNA4,KIF5A,KIF5C,STXBP5,L1CAM,SYTL4,LSAMP,MAOB,MAP2,MAPT,MEIS1,SCG3,DDX25,MYT1,NAP1L2,NAP1L3,NCAM1,NCAM2,NEFM,NEK1,NELL2,NOVA1,NRCAM,PCDH9,TMOD2,SERPINE2,NALCN,PLP1,PPP2R2B,PKIA,MAPK10,PROX1,STK32A,ZIK1,EML5,PTPRZ1,RADX,ZMAT4,RET,RGS4,RGS7,NUDT11,RNASEL,RTN1,SATB1,SCN3A,MRAS,SCG5,KIF21A,CNKSR2,CXXC4,SNAP25,SNCA,SCN3B,BEX1,KIF1B,NFASC,CLASP2,EPB41L3,ZC4H2,ELOVL4,SEPT3,SYT11,NUDT10,SYT1,SYT4,CAMTA1,AGTPBP1,CUX2,BEX4,RUNDC3B,TUB,CADM1,SLAIN1,FSTL5,SLC38A1,STMN4,SCG2,MARCH8" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.63E-57 8.32E-54 3.33E-55 3.03E-54 210 423 "ASIC2,CSMD3,NDRG2,ADCYAP1R1,NME5,PCDH10,UNC79,ANK2,PPFIA2,APBA2,APBB1,VAT1L,LGR5,SLC7A14,CADPS,ASCL1,ATP1A3,CADM3,KIF1A,TTC9B,ADGRB3,BCHE,NRP2,HAP1,VSTM2A,CCK,INA,DCLK1,CHGA,CHGB,RAB3C,RAB33A,NRXN1,CLTB,SULT4A1,PICK1,CNTFR,SLC35F1,FAM171B,CRMP1,CLIP3,FEZ1,PLXNA4,ERC2,NRSN1,RIMS2,ST18,KIAA0408,HDAC9,SCRN1,DNAJC6,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SV2A,SRGAP3,DLG2,RAB39B,EBF1,ST8SIA3,SEZ6L2,EDNRB,ATL1,ELAVL2,ELAVL4,KCNMB2,DENND4A,NCALD,CEND1,EYA1,CLVS1,FABP7,CACNG3,TUBB3,TUBB4A,CORO2B,FDFT1,FGF13,SGIP1,NSG2,NSG1,TPPP3,PHYHIPL,GABRB3,GAP43,SYT17,SRRM4,IGSF5,GFRA1,GFRA2,C1QL1,RUNDC3A,PCSK1N,GNAO1,GNG3,TDRKH,B4GALNT4,GPR19,GPR22,PCLO,STMN2,GRIA2,GRIA4,CELF3,ARHGAP36,HLF,ACOT7,DISP2,LIX1,TUBB2B,KCNA4,KCNN2,KIF5A,KIF5C,KLC1,L1CAM,LMO1,SYTL4,LSAMP,LSS,PACRG,MAP2,MAP6,SCG3,TAGLN3,MYT1,NAP1L2,NCAM1,NCAM2,NEFM,NEK1,NELL2,NNAT,NPY,NOVA1,PCBP3,NTRK3,PALM,PCDH9,PDE3A,SLC10A4,PENK,TMOD2,PFKP,GDAP1L1,SERPINE2,PLP1,PMP22,PPP2R2B,PKIA,MAPK10,PROX1,PRPH,SNRK,MDGA2,STK32A,EML5,PTPRZ1,RALGDS,RADX,ZMAT4,RET,RGS4,RGS7,NUDT11,RNASEL,RTN1,SATB1,SCN2A,SCN3A,FAM19A1,MRAS,SCG5,KIF21A,MAST1,SNAP25,SNCA,SNRPN,SCN3B,NFASC,SST,EPB41L3,SEPT3,STXBP1,SYT11,NUDT10,SYN1,SYP,SYT1,SYT4,ASTN2,AGTPBP1,CUX2,PCDHB9,TNR,RUNDC3B,STXBP4,SSBP2,TMEFF2,CADM1,UCHL1,ATP6V0E2,FSTL5,DPYSL5,MEIS3,STMN4,SCG2,PCBP4,MVB12B" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.63E-57 1.34E-53 5.16E-55 4.70E-54 266 615 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,PTCHD1,PCDH19,CEP126,PCDH10,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,ATP2B2,CADM3,ATP6V1G2,KIF1A,ADAM23,CARMIL3,ADGRB3,PROM1,BMPR1B,DST,JAZF1,SGCE,CACNA1A,PTBP2,VSTM2A,CDK11B,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,SRSF11,FOXN3,SLIT2,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,CNTFR,IQCK,WHRN,SLC25A27,LETMD1,SLC4A8,NECTIN3,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,CNTNAP2,ERC2,PPP6R2,ST18,PYGO1,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,JAKMIP2,RUSC2,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,EIF4G2,ELAVL3,RGS17,BSCL2,TMEM35A,EMX2,ENO2,LRRC23,EPHA5,DENND4A,APC2,ADGRV1,CLVS1,FAM198B,FABP7,ZIC4,TAOK3,ATP8A1,CHST15,FOXG1,SEMA6C,DPYSL4,FUT9,TPPP3,NRG3,GAD1,C15orf41,SRRM4,ACSS1,KIAA1841,FAXC,GFRA1,PPARGC1A,PCDH11X,GNAO1,GPM6B,DIPK1C,PCLO,GRIK2,CACFD1,MFSD2A,CELF3,FRMD5,KLF12,IGFBPL1,HPCA,USP51,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,HES5,BRINP3,INSM1,TUBB2B,LRRTM1,KCNN3,KTN1,LSAMP,LSS,MAP2,MARK1,MEIS2,PPM1L,NRBP2,SCG3,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NASP,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,GDAP1L1,SEMA5B,TMEM38A,GPSM2,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,EPDR1,MAPK10,MDGA2,PTPRD,EML5,ENOX1,PRRT2,RFX5,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,CXXC4,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,LMBRD1,TRERF1,SOX11,GLT8D1,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,FAM168A,SYT11,RHBDL3,SYN1,SYP,ASTN2,ATP11A,SEMA4A,MCF2L,TMEM178B,ACSL6,CUX2,AZIN2,TMEM151B,PSD3,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,STMN4,TUBA1A,WNK2,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 9.55E-57 4.87E-53 1.74E-54 1.59E-53 127 185 "CPNE2,TTYH1,NDRG2,SLITRK1,ADCYAP1R1,PCDH10,LRRC4C,CASK,ASCL1,PCDHGB4,ASTN1,ADGRB1,BCHE,VXN,SEPT7,ADGRG1,NRXN1,QKI,CNTN1,AKAP7,COL9A1,SLC35F1,CREB5,NCAN,CST3,SDC3,CTNND2,RASSF2,BRINP1,DBI,NTM,OLIG1,DPP6,EDNRB,OLIG2,ETV1,FABP7,TAOK3,C1orf61,NSG2,CSPG5,FYN,PHYHIPL,SALL3,DNER,GATM,PCDH17,HEPN1,LUZP2,DCLK2,GNG4,GPM6A,GPM6B,GPR17,GRIA2,GRIA4,GRM5,SCRG1,ATCAY,GAREM2,HES5,BRINP3,LRRTM3,KCND2,KLRC2,FGFBP3,LSAMP,SHC3,MMP16,MT3,SCG3,BEX5,FXYD6,NCAM1,NCAM2,NFIA,NFIX,NKX2-2,NOVA1,NTRK2,NTRK3,OMG,PDGFRA,NLGN3,SERPINE2,PLP1,PLXNB1,PMP2,SPATA6,NXPH1,NKAIN4,MASP1,PTCH1,PLPPR1,PTN,PTPRD,PTPRZ1,PID1,ARID4A,RIT2,SOX8,S100B,SCN3A,HES6,SOX6,DOCK10,BCAN,ST8SIA1,SLC1A2,SLC1A3,EPN2,SIRT2,SOX2,ZCCHC24,SOX10,NPAS3,SMOC1,SULF2,FAM168A,ADGRL3,ZEB1,SLC44A1,TMOD1,SEZ6L,ANKS1B,PCDH15,ITM2C" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.55E-57 4.87E-53 1.74E-54 1.59E-53 127 185 "CPNE2,TTYH1,NDRG2,SLITRK1,ADCYAP1R1,PCDH10,LRRC4C,CASK,ASCL1,PCDHGB4,ASTN1,ADGRB1,BCHE,VXN,SEPT7,ADGRG1,NRXN1,QKI,CNTN1,AKAP7,COL9A1,SLC35F1,CREB5,NCAN,CST3,SDC3,CTNND2,RASSF2,BRINP1,DBI,NTM,OLIG1,DPP6,EDNRB,OLIG2,ETV1,FABP7,TAOK3,C1orf61,NSG2,CSPG5,FYN,PHYHIPL,SALL3,DNER,GATM,PCDH17,HEPN1,LUZP2,DCLK2,GNG4,GPM6A,GPM6B,GPR17,GRIA2,GRIA4,GRM5,SCRG1,ATCAY,GAREM2,HES5,BRINP3,LRRTM3,KCND2,KLRC2,FGFBP3,LSAMP,SHC3,MMP16,MT3,SCG3,BEX5,FXYD6,NCAM1,NCAM2,NFIA,NFIX,NKX2-2,NOVA1,NTRK2,NTRK3,OMG,PDGFRA,NLGN3,SERPINE2,PLP1,PLXNB1,PMP2,SPATA6,NXPH1,NKAIN4,MASP1,PTCH1,PLPPR1,PTN,PTPRD,PTPRZ1,PID1,ARID4A,RIT2,SOX8,S100B,SCN3A,HES6,SOX6,DOCK10,BCAN,ST8SIA1,SLC1A2,SLC1A3,EPN2,SIRT2,SOX2,ZCCHC24,SOX10,NPAS3,SMOC1,SULF2,FAM168A,ADGRL3,ZEB1,SLC44A1,TMOD1,SEZ6L,ANKS1B,PCDH15,ITM2C" Coexpression Atlas PCBC_EB_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_1000 PCBC 2.01E-56 1.03E-52 3.54E-54 3.23E-53 365 997 "KCNH8,SLITRK1,CCDC85A,GALNT13,UNC5A,PCDH19,AGT,KCTD16,SORCS2,DISP3,SPARCL1,PDZD4,DPP10,LRCH2,LRRC4C,ASCL1,DACT3,RASL11B,KIF1A,TTC9B,CARMIL3,BMP7,CACNA1G,MYRF,CDK5R2,CABP7,CAMK2A,BRSK2,CBLN1,CDH8,CDH10,CDH18,LGI1,NOG,CHGA,SYNPR,CHRNA4,LHX2,TMEM59L,SULT4A1,IGLON5,CNR1,CNTFR,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,SNCAIP,TENM4,ATRNL1,NCAN,RIMS4,PHACTR3,CNTNAP2,CFAP61,ST18,PYGO1,BOC,RIMS3,BRINP1,DCC,DCT,ZNF804A,LYPD1,SNAP91,SPOCK3,KIF19,HS3ST4,CDON,FAM57B,DUSP9,USH1C,EDN3,SEMA3D,EFNA2,EFNB3,LINC00599,ELAVL2,ELAVL3,ELAVL4,NCALD,APC2,ADGRV1,NRN1,CLVS1,FABP7,TMEM132C,ZIC4,ZMYND10,SPSB4,ACTL6B,HPCAL4,C1orf61,FOXF2,ATP13A4,PSD2,AFF2,SYT3,NSG2,DACH2,CSPG5,DLL3,B3GAT1,TPPP3,TMEM151A,PHYHIPL,MEGF10,GABRA2,GABRA3,CHL1,ILDR2,NKX6-2,ARPP21,SALL3,GAP43,SRRM4,CPLX2,DNER,GCK,CYP46A1,GFRA1,GFRA2,FREM1,RUNDC3A,TTBK1,PCSK1N,GNG3,GPM6A,GPM6B,CCDC184,LPAR4,STMN2,GRIA1,GRIA2,C1QL4,GRIA4,GRIK1,GRIK3,GRM8,LINGO1,GUCY1A1,TMEM179,CELF3,WIF1,UBE2QL1,NXPH2,BACH2,SCRG1,HPSE2,IGFBPL1,HP,CELF5,ATCAY,BTBD17,C2orf72,IGF1,NKD1,KIAA1755,PLD5,HES5,LIX1,SCRT2,INSM1,ITIH2,KCNA2,CDH20,KCNA6,KCNC1,KCND2,KCND3,CLVS2,KCNJ3,KCNJ4,KCNK2,KCNK3,KCNMA1,KCNN1,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,PACRG,CLEC18A,C1orf194,MAP6,MAPT,MATN2,LRP1B,SCG3,TAGLN3,MTTP,RSPO2,MYBPC1,MYH6,MYL3,MYT1,FXYD7,NCAM1,NEFM,NELL1,NELL2,NEUROD1,NHLH1,NNAT,NPY,NPPA,NTRK2,NTRK3,OLR1,OMG,KCNK10,PAX6,PCDH8,PDE1A,PDGFRA,PENK,DUSP26,GDAP1L1,SEMA5B,CAMKV,PLCL1,PLP1,HMGCLL1,PDZRN4,PRRX1,SDK2,NECAB2,MAGEL2,FAT3,POU3F2,POU3F4,PPP2R2B,NKAIN4,VSTM2L,RAB39A,PRPH,RELN,KLK6,PSD,LAMA1,PTH1R,ELOVL2,PTN,PTPRD,PTPRN,PTPRO,TMEM145,NKAIN1,TMEM255A,FAT4,DUSP15,PRRT2,RFX4,RGS4,ZFHX4,ROBO2,MRAP2,RPE65,HUNK,KCNIP1,RTN1,RXRG,S100B,AMER2,SEMA6D,LRFN5,LINC00461,TNFRSF19,SMPD3,TMEM200C,PPM1E,ST8SIA1,SLC1A6,SLC6A1,PKNOX2,LRRC55,SLC8A2,SLC8A3,TMEM132D,EFHD1,SLIT1,SLN,CXXC4,SORCS3,DMRTC1,RIMS1,SNAP25,CABCOCO1,ANKFN1,FAIM2,SOX1,MYT1L,SOX3,SOX5,KIF21B,SOX10,SOX11,NMNAT2,ENKUR,SPP1,PEG10,LMO3,CLSTN2,SMOC1,SST,SSTR2,SEPT3,ABCC8,ZFR2,RHBDL3,SYP,SYT1,SYT4,SYT5,TAC1,TAC3,CNTN2,ADGRL3,VWA3A,PCDHGB6,TMEM151B,CCDC173,TF,DNAH7,CHST8,CRB1,ASXL3,DAAM2,RIMBP2,CSMD1,SEZ6L,RASD2,TRH,FNDC5,RFTN2,RPRM,AMOT,FLRT1,FAM181B,RBFOX3,WNT7A,ZIC1,ZIC3,KCNT2,CFAP52,FMN2,CRB2,MKRN3,CELF4,REEP1,DPYSL5,SHD,STMN4,SCG2,GAL3ST3,TMEM163,SLC17A6,DNAH10,SLC39A12,CBLN2,FAM181A,PRRT4,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 7.03E-56 3.58E-52 1.19E-53 1.09E-52 284 689 "DPF1,TTYH1,ABAT,SYN3,ABHD6,NCKAP5,GALNT16,SLITRK1,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,APLP1,MAGEE2,PHYHD1,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CADM3,ADAM23,CARMIL3,ADGRB3,BMPR1B,DST,JAZF1,SGCE,CACNA1A,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,ADGRG1,FOXN3,JAM2,SLIT2,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,SLC4A8,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,CNTNAP2,ERC2,PPP6R2,ST18,NOS1AP,PYGO1,HDAC9,TOX,PHF19,SCRN1,BRINP1,DNAL1,DCC,JAKMIP2,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,CASP8AP2,DTNA,MAMLD1,CACNG7,ING4,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,NSRP1,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,FOXG1,SEMA6C,DPYSL4,NSG1,FUT9,B3GAT1,NRG3,SRRM4,ACSS1,FAXC,GFRA1,CSDC2,PPARGC1A,MAP7D2,GPM6B,DIPK1C,CECR2,PCLO,CACFD1,MFSD2A,LINGO1,FRMD5,KLF12,AGBL5,IGFBPL1,HPCA,USP51,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,KIF5C,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NASP,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,NLGN3,SEMA5B,ZFYVE21,TMEM38A,GPSM2,SLC25A23,MAPKAP1,MAGEL2,SLC36A4,FAT3,POU6F1,TATDN3,PPP3CC,EPDR1,MAPK10,MDGA2,PXK,PTPRD,ENOX1,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,TRERF1,SOX11,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,DIP2A,SEPT3,FAM168A,KLHL7,SYT11,RHBDL3,SYN1,SYP,ASTN2,ATP11A,SEMA4A,ROBO3,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SPIRE1,SHD,STMN4,TUBA1A,VPS35L,WNK2,PIANP,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 8.74E-56 4.46E-52 1.44E-53 1.31E-52 293 723 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,CNIH2,APLP1,MAGEE2,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,ASCL1,NCOA1,ASTN1,CADM3,ATP6V1G2,ADAM23,CARMIL3,ADGRB3,BMPR1B,DST,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,SRSF11,JAM2,SLIT2,LHX2,KMT2C,KIAA1549L,NRXN1,NRXN2,CLTB,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,SLC4A8,MFSD4A,SLC35F1,FAM171B,CREB5,CLIP3,AATK,CSF2RA,FEZ1,CNTNAP2,ERC2,PPP6R2,ST18,RUBCN,PYGO1,HDAC9,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ING4,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,FGFR1,FOXG1,SEMA6C,DPYSL4,NBEA,SPECC1,FUT9,NRG3,JPH4,SRRM4,ACSS1,GATM,FAXC,GFRA1,CSDC2,PPARGC1A,GPM6B,DIPK1C,PCLO,GRIK2,CACFD1,MFSD2A,RABL2A,LINGO1,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,MSR1,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NNAT,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,ZFYVE21,TMEM38A,GPSM2,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,PPP3CC,NKAIN4,EPDR1,MAPK10,MDGA2,PXK,PTPRD,ENOX1,FEZF2,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,SALL1,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,NTNG1,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,DOP1A,TRERF1,SOX5,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF708,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SHD,STMN4,TUBA1A,VPS35L,WNK2,PIANP,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 2.93E-55 1.49E-51 4.67E-53 4.26E-52 299 749 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,SLC25A25,GALNT16,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,APLP1,MAGEE2,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CADM3,ADAM23,CARMIL3,ADGRB3,DST,JAZF1,SGCE,CACNA1A,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,JAM2,SLIT2,LHX2,KMT2C,KIAA1549L,NRXN1,NRXN2,CLTB,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,SLC4A8,MFSD4A,SLC35F1,FAM171B,CREB5,CLIP3,AATK,CSF2RA,FEZ1,ATRNL1,CNTNAP2,ERC2,PPP6R2,ST18,RUBCN,PYGO1,HDAC9,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ING4,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,ADGRV1,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,FDFT1,FGFR1,FOXG1,DPYSL4,NBEA,SPECC1,NSG1,FUT9,NRG3,JPH4,SRRM4,ACSS1,FAXC,GFRA1,CSDC2,PPARGC1A,GLDC,MAP7D2,GPM6B,DIPK1C,PCLO,GRIK2,CACFD1,MFSD2A,LINGO1,FRMD5,KLF12,BACH2,AGBL5,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNH2,KCNN3,KHK,CREG2,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,MSI1,ADAM22,MSR1,NRBP2,TAGLN3,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NNAT,NTRK2,NUCB2,GPR137C,PAK3,CNTN3,PAX6,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,ZFYVE21,TMEM38A,GPSM2,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU3F4,POU6F1,PPP3CC,NKAIN4,EPDR1,MAPK10,MDGA2,PXK,PTPRD,ENOX1,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,DOP1A,TRERF1,SOX5,SOX11,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,SSBP2,TUB,TUBB2A,UBE2H,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZIC3,ZNF708,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SHD,STMN4,TUBA1A,VPS35L,WNK2,KLHDC1,PIANP,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 3.85E-55 1.96E-51 5.95E-53 5.42E-52 294 731 "DPF1,TTYH1,SYN3,ABHD6,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,ERMN,PTCHD1,PCDH19,WDR35,SPOP,PCDH10,LTBP4,GPRASP2,CDC42BPA,ANK2,PPFIA2,CNIH2,APLP1,MAGEE2,LRRC4C,TNRC6C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CADM3,ATP6V1G2,ADAM23,CARMIL3,ADGRB3,DST,MTMR3,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,JAM2,SLIT2,LHX2,KMT2C,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,SLC4A8,ZNF521,MFSD4A,SLC35F1,FAM171B,CREB5,CLIP3,AATK,CSF2RA,FEZ1,PDE4DIP,CNTNAP2,SLITRK5,ERC2,ST18,RUBCN,PYGO1,GPRASP1,KATNAL2,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,EFNA3,ING4,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,MED12L,FOXG1,DPYSL4,SPECC1,FUT9,TPPP3,NRG3,SRRM4,ACSS1,FAXC,GFRA1,PPARGC1A,PCDH11X,GNAO1,GPM6B,DIPK1C,PCLO,CACFD1,MFSD2A,FRMD5,KLF12,AGBL5,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,ZIC5,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,NRBP2,TAGLN3,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,FAM216A,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,PPP3CA,PPP3CC,EPDR1,MAPK10,GDPD1,SNRK,MDGA2,PXK,PTPRD,PTPRZ1,ENOX1,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,SBF1,CSRNP3,ATXN1,LRRTM4,LINC00461,ZFP30,PPP1R9A,ARX,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,GKAP1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,TRERF1,SOX5,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,KAT6B,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZIC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SHD,STMN4,TUBA1A,VPS35L,TMEM163,WNK2,MVB12B,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.92E-55 3.53E-51 1.04E-52 9.46E-52 171 312 "TMEM132B,TMCC3,KIDINS220,AP2A2,GPR158,PCDH10,SYT13,ANK2,ANK3,PPFIA2,APLP1,APP,CADPS,ZBTB10,B3GALT2,CDK5R1,GPC2,CACNA1E,RUNX1T1,INA,SEPT7,LONRF2,DCLK1,ADGRG1,CHGB,NRXN1,NRXN2,CNTN1,CREM,CRHBP,CRMP1,NCAN,PLXNA4,ERC2,RIMS2,KIAA0408,AIF1L,DCC,PITPNC1,DNAJC6,CEP170,SNAP91,NTM,DPP6,EIF4G2,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EN2,RCAN2,EPHA5,ERBB4,FABP7,TUBB3,TAOK3,KAT8,FGF13,PDLIM5,NSG2,NSG1,PNMA2,FUT9,AP4B1,PHYHIPL,DKK3,GABRB3,TRAF3IP2,JPH4,GAP43,SRRM4,DNER,GFRA1,OS9,GNAO1,GNG3,GPM6A,STMN2,GRB10,GRIA2,IL1RAPL1,CELF3,TOX2,SCRG1,NEGR1,CELF5,INSM1,KIF5C,KLC1,L1CAM,LSAMP,MAP6,CD200,TAGLN3,TCEAL5,BEX5,NAP1L3,NCAM1,NNAT,IGSF11,CHAMP1,ZDHHC22,PBX1,PCSK2,ENPP2,SLC10A4,GPR173,GNG2,TMOD2,CDK14,RETREG1,PDZRN4,LRP12,FAT3,POU3F2,POU6F1,PRKACB,PKIA,PTPRO,RALGDS,REV3L,GTDC1,ROBO1,ROBO2,WLS,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SMPD3,SCG5,WDR47,NAPB,TET1,CPEB4,SCN3B,MYT1L,KIF21B,SOX11,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,CLASP2,SEPT3,SYT1,SYT4,TAC1,TMEM178B,KIAA1107,EHBP1,AKNA,RBFOX2,SEZ6L,RUNDC3B,RUSC1,TUB,TUBB2A,TMEFF2,UCHL1,CELF4,REEP1,DPYSL5,STMN4,TUBA1A,PAK5,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K2 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.20E-54 6.10E-51 1.74E-52 1.59E-51 274 660 "DPF1,TTYH1,SYN3,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,KIAA1211,PTCHD1,MTUS1,PCDH19,WDR35,PCDH10,GPRASP2,ANK2,PPFIA2,MAGEE2,LRRC4C,SHTN1,SEMA4G,MADD,ASCL1,NCOA1,ASTN1,KIF1A,ADAM23,CARMIL3,ADGRB3,BCL7A,JAZF1,SGCE,CACNA1A,DIRAS1,HAP1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,ADGRG1,SRSF11,JAM2,SLIT2,NRXN3,KIAA1549L,CLTB,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,LETMD1,SLC4A8,SLC35F1,FAM171B,CREB5,AATK,FEZ1,CNTNAP2,ERC2,RIMS2,PPP6R2,ST18,PYGO1,TOX,PHF19,SCRN1,BRINP1,DNAL1,DCC,JAKMIP2,RUSC2,FBXO25,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,DMD,CD99L2,DTNA,MAMLD1,ELAVL3,CERCAM,ELAVL4,BSCL2,TMEM35A,C8orf37,OLIG2,ENO2,EPHA5,EPHB1,DENND4A,APC2,ADGRV1,CLVS1,FAM198B,FABP7,TUBB3,TAOK3,ATP8A1,CHST15,MED12L,FOXG1,SEMA6C,DPYSL4,NBEA,ATP2C1,NSG1,TPPP3,NRG3,GAD1,GAD2,SRRM4,ACSS1,KIAA1841,FAXC,PPARGC1A,RUNDC3A,GNG3,GPM6A,GPM6B,DIPK1C,PCLO,GRIK2,CACFD1,RNF165,MFSD2A,FAM222A,CELF3,TOX2,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CELF5,ATCAY,EID2B,IGSF1,HES5,BRINP3,INPP5B,INSM1,TUBB2B,KIF5C,LSAMP,LSS,MAP2,MARK1,MBP,SHC3,MEIS2,MGAT3,SCG3,TAGLN3,SAMD14,MXI1,LINC00672,NEXMIF,MYT1,NCAM1,NCAM2,NELL2,NFIA,NNAT,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,GDAP1L1,SEMA5B,TMEM38A,GPSM2,SMOX,PLXNB1,SLC36A4,FAT3,POU6F1,TATDN3,PPP3CC,EPDR1,MAPK10,GDPD1,SLC22A23,APTX,MDGA2,ELOVL2,PTPRD,ENOX1,RFX5,TMEM206,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LINC00461,HSPA4L,SCG5,ZFP30,KIF21A,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,SNAP25,MAPKBP1,SP4,GLT8D1,LHFPL4,NPAS3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,FGD4,SYNE2,RHBDL3,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,AZIN2,TMEM151B,PSD3,AKNA,CCDC173,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,KCNE5,SSBP2,TUB,TUBB2A,UBE2H,UCHL1,MGAT5B,PLPPR2,WNT7A,NPDC1,TRIM9,FMN2,LYPD6,CELF4,DPYSL5,STMN4,TUBA1A,VPS35L,WNK2,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.49E-54 7.61E-51 2.11E-52 1.93E-51 358 984 "TTYH1,ABCF1,ACLY,ABHD6,NDRG2,FMNL2,KLHL32,GALNT16,SLITRK1,ERMN,MTUS1,PCDH19,ARHGAP20,LTBP4,GPRASP2,CDC42BPA,ANK2,EPB41L5,PHYHD1,SHTN1,CDK10,PDXK,MADD,ZFYVE28,ASCL1,ASTN1,ATP1A3,ATP2B2,ATP6V1G2,KIF1A,ADAM23,CARMIL3,ADGRB2,ADGRB3,PROM1,BMPR1B,SCAPER,C1QC,IL33,CACNA1A,CACNA2D1,DIRAS1,HAP1,PTBP2,MAP7,INA,CDK11B,LRBA,CDC25B,CDH2,KCNAB3,CDH8,MAGI1,CDO1,CRLF1,DIS3L,ADGRG1,SRSF11,JAM2,LHX2,NRXN3,KIAA1549L,NRXN2,C4orf33,CNTFR,IQCK,COL4A5,IGDCC3,SLC35F1,FAM171B,CREB5,CLIP3,CSF1R,FEZ1,NCAN,CNTNAP2,FAM169A,SLITRK5,ERC2,PHF14,CTNND2,RIMS2,ST18,RUBCN,KATNAL2,TOX,SCRN1,DNAL1,JAKMIP2,MYEF2,FBXO25,DDX46,SRGAP3,RABGAP1L,CCDC3,DLX1,RAB39B,DMD,CASP8AP2,DTNA,MAMLD1,EDNRB,SEMA3D,FSD1L,PLXNC1,EIF5,ELAVL2,ELAVL3,ELAVL4,RGS17,ELN,C8orf37,EMX2,OLIG2,EPB41,LRRC17,SEZ6,EPHA5,EPHB1,GPHN,RRAGB,ADGRV1,FABP7,ACSL4,TUBB3,TUBB4A,TAOK3,CORO2B,ATP8A1,FCGRT,FDFT1,MED12L,FGF11,FGF12,FGFR3,FHL1,HPCAL4,FOXG1,DPYSL4,SPECC1,KHDRBS3,DLL3,FUT9,B3GAT1,ADGRA1,TPPP3,ABLIM2,FYB1,PHYHIPL,GABRB3,ILDR2,GAD1,GAD2,ARPP21,SALL3,SRRM4,ACSS1,STARD10,KIAA1841,GATM,PCDH17,PPARGC1A,ZNF276,GLDC,DBF4,GLRB,TOX3,PCDH11X,MAP7D2,GNAO1,GNG3,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,NR3C1,CIT,GSN,RNF165,TMEM25,MFSD2A,RABL2A,SOX21,PSIP1,CELF3,TOX2,FRMD5,DDX19B,SYNPO,IGFBPL1,USP51,CELF5,ATCAY,KNDC1,LRRCC1,IGSF1,HES5,LIX1,IL11RA,INSM1,TUBB2B,LRRTM1,KIF5C,KTN1,LSAMP,LSS,MAP2,MBP,TM6SF1,SHC3,MEIS2,SRSF12,MID1,SCG3,MXI1,MYT1,NASP,NCAM2,NEFM,NELL2,NFIA,NFIX,NOVA1,CLEC9A,NRCAM,NTRK2,IGSF11,ODF2,OPA1,GPR137C,PAK3,PAX6,PCDH9,PRTG,PDE3B,SEMA5B,GPSM2,SLC25A23,MAGEL2,FAT3,POU3F4,CRLS1,PKIA,MAPK10,DIRAS2,PRODH,GDPD1,VPS13C,MDGA2,CNTLN,ELOVL2,EML5,PTPRZ1,STRC,IQSEC3,ENOX1,FEZF2,RBBP6,RBBP8,ZMAT4,DUSP15,RFX4,FBXW7,MEG3,SOX8,RTN1,STX1B,CCDC112,SAFB,SALL1,ATXN1,LINC00461,SOX6,HSPA4L,SCG5,ZFP30,KIF21A,PPM1E,ARX,NTNG1,FHOD3,NLGN1,FAM214B,GKAP1,MAST1,SNAP25,DOP1A,TRERF1,SOX2,SOX5,BDP1,LHFPL4,NPAS3,LMO3,C11orf87,LARP4,ZSCAN29,SEPT3,AJAP1,GSE1,ACSBG1,KLHL7,SYT11,FGD4,ZFR2,SYNE2,VPS13A,SYN1,SYP,ANKRD28,ROBO3,WWC1,WASHC4,PHF24,FAM189A1,AHCYL2,CCDC173,AKTIP,NR2E1,TMOD1,KAT6B,TNNT1,PRMT8,STXBP4,TRPS1,TUB,SLAIN1,FAM181B,USP1,MGAT5B,TSPAN11,RBFOX3,WNT7A,ZIC1,ZIC2,ZIC3,ZNF23,FMN2,LYPD6,CELF4,ZBTB16,REEP1,DPYSL5,SPIRE1,PMEPA1,STMN4,STOX2,GAL3ST3,WNK2,DNAH10,FZD3,CERS6,NETO2,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 200 GSE76381_iPSMoleculeCountsPMLog2 2.07E-54 1.05E-50 2.85E-52 2.59E-51 264 625 "CSMD2,RNF157,SLC12A5,SNX30,ALCAM,GOLGA7B,SYT13,ANK2,ANK3,C6orf89,PPFIA2,APBB1,DGKD,VAT1L,APP,MTMR9,CADM3,KIF1A,ADAM23,SEC11C,CDK5R1,SGCE,GPC2,BAIAP3,CACNA1A,CALB2,CAMK2B,VSTM2A,MAP7,RUNX1T1,INA,SEPT7,CDC25B,LONRF2,CDC42,DCLK1,CCPG1,ADGRG1,CHGA,CHGB,CLCN3,CLCN4,NRXN1,CNTN1,SLC4A8,ABI3BP,PREPL,CRMP1,SEC24C,FEZ1,PLXNA4,PHF14,PNPLA8,SLC45A1,CTNND2,KIAA0408,DNAJC6,ELMO1,MAGI2,TMEM130,SPOCK3,SV2A,RABGAP1L,KBTBD11,NYAP1,TRAPPC9,CPEB2,DPYSL2,RCAN1,EDIL3,SEZ6L2,EEF1A2,EFNA3,KMT5B,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,SLC43A2,ERBB4,NCALD,CLVS1,TUBB4A,PRMT5,OLFM1,FGF12,ACTL6B,HPCAL4,AGAP3,FAM49B,NPTN,NSG2,NSG1,PNMA2,SARAF,TVP23A,OGA,DKK3,GABRA1,GABRB1,GABRB3,GABRG2,NCKAP1,GAP43,SRRM4,DNER,RAB30,MAP7D2,GNAO1,GNG3,GPM6A,PCLO,STMN2,TPPP,GRIA2,GRIA4,NR3C1,BTN2A1,PTPRT,KIF3A,RNF165,LINGO1,CELF3,UBE2QL1,NEGR1,CELF5,C2CD4C,KCNC2,GPR62,KCNH2,KHK,KIF5C,KLC1,CAMK2N2,LSAMP,MAP4,MAP6,MARK1,CD200,GIT1,SCG3,SAMD14,MYO5A,BEX5,HNRNPM,FXYD6,NCAM1,NELL2,NNAT,NRCAM,KSR2,PAK3,PCDH9,PCMT1,PCSK1,GNG2,TMOD2,SNX10,RETREG1,HMGCLL1,MINDY2,PPP2R2B,VSTM2L,PRKACB,PKIA,PRKCZ,PSD,DEF8,PTPRN,MARCH1,RAB3A,RAB5B,RALGDS,RAP1GAP,ARID4A,REV3L,RGS4,TTLL7,RTN1,CSRNP3,SCN2A,SCN3A,LRRTM4,SMPD3,MRAS,SCG5,CPEB3,ST8SIA1,WDR47,CCDC88A,NAPB,ZNF667,SMARCA4,RIMS1,SNAP25,MAPKBP1,SNCA,FAIM2,SCN3B,MYT1L,KIF21B,NMNAT2,MYCBP2,ERC1,PEG10,BEX1,KIF1B,IQSEC2,NPAS3,SRPK2,CLASP2,POGZ,SS18,NACAD,SEPT8,SEPT3,STXBP1,SYN2,SYP,SYT1,SYT4,DDHD2,CAMSAP2,FBXW11,TCEA1,TRIM2,PCDHA7,SIK3,ATP13A2,MTMR14,ASXL3,R3HDM1,RBFOX2,NTSR2,RUSC1,SSBP2,TTC3,TUBB2A,FAM155A,UCHL1,DNAJC12,VGF,MEAF6,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,DPYSL5,LRP8,STMN4,TUBA1A,SCG2,MPPE1,C12orf4,MRPL47,RTN4,CERS6,FAM219B,NETO1,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 4.18E-54 2.13E-50 5.60E-52 5.11E-51 128 194 "TMEM132B,TMCC3,KIDINS220,ALCAM,SYT13,ANK2,ANK3,APBB1,APP,CADPS,KIF1A,SEC11C,CALB1,RUNX1T1,INA,SEPT7,LONRF2,CDC42,CHGB,NRXN1,TMEM59L,CNTN1,CRMP1,PLXNA4,SDC3,CALY,KIAA0408,DNAJC6,TMEM130,SNAP91,SV2A,SEZ6L2,EFNB3,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,DMTN,EPHA5,FGF13,HPCAL4,NSG2,NSG1,PNMA2,DKK3,GABRB3,GAP43,DNER,PCDH17,GNAL,GNAO1,GNG3,GPM6A,PCLO,STMN2,GRIA2,KIF3A,CELF3,ACOT7,NEGR1,CELF5,ATCAY,KIF5C,KLC1,MSANTD3-TMEFF1,LSAMP,MARK1,SCG3,MYO5A,BEX5,FXYD6,NCAM1,PAK3,PBX1,PCSK1,GNG2,TMOD2,PPP2R2B,PKIA,PTPRN,REV3L,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,SLC1A2,WDR47,NAPB,CPEB4,SNAP25,SNCA,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SRPK2,CLASP2,SEPT3,STXBP1,SYP,SYT1,SYT4,KIAA0930,PCDHA7,ATP13A2,RBFOX2,TUBB2A,CADM1,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,STMN4,SCG2,RTN4,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 4.58E-54 2.33E-50 5.98E-52 5.45E-51 273 660 "DPF1,TTYH1,ABAT,SYN3,ABHD6,NCKAP5,GALNT16,CCDC85A,RNF157,ERMN,PTCHD1,MTUS1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,CDC42BPA,ANK2,PPFIA2,APLP1,MAGEE2,PHYHD1,LRRC4C,SHTN1,SEMA4G,MADD,RGS20,NCOA1,ASTN1,CCDC181,CADM3,ADAM23,CARMIL3,ADGRB3,BMPR1B,DST,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,FOXN3,JAM2,SLIT2,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,IQCK,WHRN,SLC25A27,LETMD1,SLC4A8,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,CNTNAP2,ERC2,PPP6R2,ST18,RUBCN,HDAC9,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,WDR20,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ELAVL3,CERCAM,RGS17,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,CEND1,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,FOXG1,CAP2,SEMA6C,DPYSL4,FUT9,TPPP3,NRG3,SRRM4,ACSS1,FAXC,GFRA1,CSDC2,PPARGC1A,PCDH11X,GPM6B,DIPK1C,PCLO,CACFD1,MFSD2A,LINGO1,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,TUBB2B,LRRTM1,KCNN3,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,ADAM22,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,SMOX,SLC25A23,MAPKAP1,NECAB2,SLC36A4,FAT3,POU6F1,TATDN3,EPDR1,MAPK10,MDGA2,PXK,PTPRD,PTPRZ1,ENOX1,PRRT2,RFX5,PBRM1,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,ZFP30,PPP1R9A,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,TRERF1,GLT8D1,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,FAM168A,SYT11,RHBDL3,SYN1,SYP,ASTN2,ATP11A,ANKRD12,SEMA4A,MCF2L,TMEM178B,KIAA1107,ACSL6,CUX2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,FLRT1,MGAT5B,PLPPR2,CCDC136,RBFOX3,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SHD,STMN4,TUBA1A,VPS35L,WNK2,PIANP,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.70E-54 2.40E-50 5.99E-52 5.46E-51 126 189 "TMEM132B,TMCC3,KIDINS220,PCDH10,ANK2,ANK3,PPFIA2,APLP1,APP,CADPS,CDK5R1,GPC2,CACNA1E,RUNX1T1,INA,SEPT7,DCLK1,CHGB,NRXN1,NRXN2,CNTN1,CRMP1,NCAN,PLXNA4,ERC2,RIMS2,KIAA0408,DCC,CEP170,SNAP91,NTM,DPP6,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EN2,EPHA5,ERBB4,FABP7,TUBB3,FGF13,NSG2,NSG1,FUT9,PHYHIPL,DKK3,GABRB3,GAP43,SRRM4,DNER,GFRA1,GNAO1,GNG3,GPM6A,STMN2,GRIA2,CELF3,TOX2,NEGR1,INSM1,KIF5C,KLC1,L1CAM,LSAMP,CD200,TCEAL5,BEX5,NAP1L3,NCAM1,NNAT,PBX1,PCSK2,SLC10A4,GNG2,TMOD2,CDK14,PDZRN4,FAT3,POU3F2,PRKACB,PKIA,PTPRO,RALGDS,REV3L,ROBO1,ROBO2,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SMPD3,SCG5,WDR47,CPEB4,SCN3B,MYT1L,KIF21B,SOX11,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SEPT3,SYT1,SYT4,TAC1,TMEM178B,KIAA1107,EHBP1,RBFOX2,SEZ6L,TUBB2A,TMEFF2,UCHL1,CELF4,REEP1,DPYSL5,STMN4,TUBA1A,PAK5,NETO2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.50E-53 1.28E-49 3.11E-51 2.83E-50 183 355 "RBM10,KIDINS220,PCDH10,DOC2A,AMPH,ANK2,ANK3,SMIM29,PPFIA2,TNRC6C,TMEM108,CCDC181,ATP2B1,CDK5R1,SCAPER,CACNA1A,CACNA1B,CACNA1E,CAMK2B,RUNX1T1,FMNL3,INA,NEURL1,CDH8,DCLK1,ARHGAP33,DLGAP3,NRXN1,NRXN2,RCHY1,ACBD5,PREPL,CRMP1,TENM4,VCAN,NCAN,PDE4DIP,ERC2,RIMS2,PYGO1,KIAA0408,GPRASP1,BRINP1,CEP170,TMEM130,SNAP91,NTM,ARNT2,DYNC1I1,DPP6,FIS1,EDIL3,YAF2,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EPB41L1,EPHB1,TUBB3,TAOK3,ATP5PD,NBEA,ARFGAP2,NSG2,NSG1,BRSK1,GABRB1,GABRB3,GAD1,JPH4,GAP43,ATP8A2,SRRM4,DNER,PCDH17,GNAO1,PRRC2B,GPM6A,B4GALNT4,PCLO,CNTRL,STMN2,GRIA2,C1QL4,GRM5,KIF3A,RNF165,NEGR1,CPT1C,AGFG1,CELF5,ATCAY,LRRTM3,CDH20,KCND2,CREG2,KIF5C,L1CAM,LSAMP,ZFYVE27,MAP6,CHIC1,MEIS2,MKLN1,CD200,NEXMIF,NAP1L3,NCAM1,NELL1,NKX2-2,NNAT,NOVA1,OPCML,PCDH9,PDPK1,GNG2,TMOD2,RETREG1,PDZRN4,LRRN3,PKIA,PRKCB,SLC22A23,EML5,PTPRN2,ARID4A,RBBP6,REV3L,ZFHX4,ROBO1,ROBO2,RTN1,ZNF568,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SOX6,PUF60,KIF21A,SLC1A2,SLC8A1,CCDC88A,SHANK2,CPEB4,GKAP1,SMARCC2,MAPKBP1,SCN3B,MYT1L,KIF21B,SOX11,MYCBP2,ERC1,NPAS3,PHLDB1,SEPT3,STXBP1,SYP,SYT1,TAC1,ANKRD12,CAMTA1,CAMSAP2,KIAA1107,SYNE1,ARHGEF12,TMEM9,KCTD2,RBFOX2,CADM1,UCHL1,CELF4,REEP1,STMN4,TMEM178A,PAK5,CERS6,NETO2,SLC4A10" Coexpression Atlas PCBC_ratio_EB amniotic fluid MSC_vs_EB blastocyst_cfr-2X-p05 EB amniotic fluid MSC_vs_EB blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.38E-53 2.74E-49 6.53E-51 5.95E-50 292 738 "DPF1,TTYH1,GPRIN1,SLC25A25,PLEKHG5,GALNT16,ADCYAP1R1,ADD2,AXIN2,UNC5A,KIAA1211,SLC44A5,CASKIN1,SORCS2,DISP3,CNIH2,APLP1,CACHD1,ARHGDIG,CADPS,RASL11B,ASTN1,ATP1A2,ATP1A3,RNF182,CADM3,ATP6V1G2,KIF1A,CARMIL3,ADGRB1,ADGRB2,MIR9-3HG,BCL7A,CDK5R1,NIPA1,GPC2,WASF1,BAIAP3,DDR1,CACNA2D1,CALB2,CABP7,THSD7A,DIRAS1,KALRN,BRSK2,HIP1R,INA,CDC25B,DCLK1,ARHGAP33,CRLF1,ADGRG1,CBARP,JAM2,LHX2,NRXN2,TMEM59L,NGEF,DNAJB5,RAB26,CNR1,AKAP6,COL9A2,TCEAL2,CRMP1,FEZ1,LRRC3B,RIMS4,CTNND2,FAM131B,KIAA0408,TOX,RASSF2,RIMS3,SPOCK2,BRINP1,DCT,JAKMIP2,MYEF2,SNAP91,SRGAP3,TMCC2,NYAP1,CDON,FAM57B,EBF1,EDNRB,ATL1,EEF1A2,FSD1L,CACNG7,EFNA3,CELSR3,EGR3,LINC00599,ELAVL2,ELAVL3,ELAVL4,ELN,TMEM35A,EMX2,RCAN2,ANKRD13B,EFS,APC2,KATNAL1,NRN1,REEP2,TUBB3,TUBB4A,CHST15,OLFM1,ACTL6B,AMOTL2,AGAP2,SEMA6C,DPYSL4,NBEA,NSG2,DACH2,GPR153,CSPG5,B3GAT1,BRSK1,PHYHIPL,GABRB3,JPH4,GAP43,SRRM4,CPLX2,DNER,FAXC,GDF1,C1QL1,RUNDC3A,TOX3,GNAO1,GNG4,GPM6A,GPM6B,CROCCP2,C1QL4,GRIK5,SERP2,GRIN2D,LINGO1,CELF3,TOX2,ARHGAP19,IGFBPL1,CPT1C,HSPA1L,ATCAY,GAREM2,ZIC5,HES5,SCRT2,INSM1,TUBB2B,ITGA7,C2CD4C,ITPKB,CDH20,KCNQ2,KIF5A,KIF5C,L1CAM,NAT8L,CLEC18A,MAP2,MAPT,MMP17,MPP2,SCG3,MYO5A,RTL5,MYT1,FXYD7,NCAM1,RCOR2,NELL2,NFIA,NHLH1,NOVA1,NOVA2,NPTX2,GPR137C,ZDHHC22,PAX6,PGAM2,DUSP26,GDAP1L1,SEMA5B,PKD1,PLXNB1,PDZRN4,PILRA,FAT3,POU3F2,FSD1,MIR124-2,NKAIN4,VSTM2L,RASGEF1B,MASP1,SLC22A23,PTPRN,TMEM145,NKAIN1,FEZF2,SLC6A15,PRRT2,RFX4,BAALC,KIAA0895L,CNTNAP3,PLPPR3,RTN1,S100B,MIR124-2HG,DRAXIN,LINC00461,HES6,SMPD3,TRIM46,SCG5,ARX,ST8SIA1,SLC4A3,WDR47,LRRC55,SLIT1,MAST1,SNAP25,SNCA,SOX2,KIF21B,SOX11,NMNAT2,NFASC,COLGALT2,LRRC4,NACAD,FCHO1,STX1A,SEPT3,SYT11,JMJD6,RHBDL3,SYP,SYT1,MTCL1,ROBO3,CNTN2,WWC1,WSCD1,CUX2,TMEM151B,CHST8,LEFTY2,ENHO,RELL2,RGMB,TRH,FNDC5,TUBB2A,TMEFF2,SLAIN1,MGAT5B,MICAL1,ZIC2,ZIC3,MICU3,ATP6V0E2,EMX2OS,NDRG4,TCEAL7,TMEM198,DPYSL5,SHD,STMN4,STOX2,SEMA3B,TMEM163,PCBP4,WNK2,SLC17A6,CASC15,VANGL2,ST8SIA2,FAM181A" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.43E-52 7.29E-49 1.69E-50 1.54E-49 287 722 "DPF1,TTYH1,ABAT,SYN3,NCKAP5,GALNT16,CCDC85A,RNF157,ADCYAP1R1,PCDH19,WDR35,ALCAM,PCDH10,LTBP4,GPRASP2,ANK2,PPFIA2,CNIH2,APLP1,MAGEE2,LRRC4C,TNRC6C,SHTN1,MADD,RGS20,NCOA1,ASTN1,CADM3,ATP6V1G2,ADAM23,CARMIL3,ADGRB3,BMPR1B,DST,MTMR3,JAZF1,SGCE,CACNA1A,DDR1,THSD7A,DIRAS1,VSTM2A,CDC25B,LONRF2,CDH8,EVI5L,NUMBL,SRSF11,FOXN3,JAM2,SLIT2,KMT2C,NRXN3,KIAA1549L,NRXN1,NRXN2,DNAJB5,IGLON5,ARHGEF6,CNTFR,IQCK,WHRN,SLC25A27,SLC4A8,ZNF521,MFSD4A,SLC35F1,FAM171B,CREB5,AATK,CSF1,CSF2RA,FEZ1,PDE4DIP,CNTNAP2,SLITRK5,ERC2,PPP6R2,ST18,RUBCN,GPRASP1,TOX,PHF19,DGKB,SCRN1,BRINP1,DNAL1,DCC,RUSC2,FBXO25,SV2A,SRGAP3,ARNT2,KBTBD11,DLX1,DMD,CD99L2,SHANK1,DTNA,MAMLD1,CACNG7,ING4,ELAVL3,CERCAM,BSCL2,TMEM35A,C8orf37,EMX2,ENO2,LRRC23,EPHA5,EPHB1,DENND4A,APC2,FAM198B,FABP7,TAOK3,ATP8A1,CHST15,FOXG1,SEMA6C,DPYSL4,SPECC1,FUT9,NRG3,SRRM4,ACSS1,FAXC,GFRA1,PPARGC1A,GNAO1,GPM6B,DIPK1C,PCLO,CACFD1,MFSD2A,LINGO1,FRMD5,KLF12,IGFBPL1,HPCA,NEGR1,CPT1C,CELF5,ATCAY,EID2B,IGSF1,BRINP3,INPP5B,TUBB2B,LRRTM1,KCNN3,LSAMP,LSS,MAP2,MARK1,MEIS2,MGAT3,MMP16,ADAM22,NRBP2,TAGLN3,SAMD14,MXI1,LINC00672,MYT1,NCAM1,NCAM2,NELL2,NFIA,NTRK2,NUCB2,GPR137C,PAK3,PCDH9,PGAM2,NLGN3,SEMA5B,TMEM38A,GPSM2,FAM216A,SMOX,SLC25A23,MAPKAP1,SLC36A4,FAT3,POU6F1,TATDN3,PPP3CA,EPDR1,MAPK10,GDPD1,SNRK,MDGA2,PXK,PTPRD,PTPRZ1,ENOX1,PRRT2,RFX5,TMEM206,TCP11L1,MEG3,RTN1,STX1B,CCDC112,CSRNP3,ATXN1,LRRTM4,LINC00461,ZFP30,PPP1R9A,ARX,FHOD3,NLGN1,SLC1A3,FAM214B,SCMH1,GKAP1,MAST1,SORCS3,SMARCD3,RCOR3,MAPKBP1,TRERF1,SOX5,GLT8D1,LHFPL4,NPAS3,LMO3,CLSTN2,NKAIN2,ZSCAN29,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,C3orf70,SYN1,SYP,ASTN2,ATP11A,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,AZIN2,TMEM151B,PSD3,AKNA,AKTIP,THRA,NACC2,DDHD1,NR2E1,KAT6B,NR2C2,PRMT8,TRPC3,SSBP2,TUB,TUBB2A,UBE2H,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,TRIM9,FMN2,LYPD6,CELF4,SHD,STMN4,TUBA1A,VPS35L,WNK2,KLHDC1,PIANP,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.51E-52 1.28E-48 2.91E-50 2.65E-49 118 173 "ASIC1,CSMD2,SLITRK1,SLC12A5,SMIM17,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,SYNPR,KIAA1549L,NRXN1,NRXN2,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,BRINP1,ZNF804A,SPOCK3,OLIG1,DPP6,RASA4,ELAVL3,ELAVL4,EN2,OLIG2,DMTN,FABP7,TAOK3,FGF12,C1orf61,NSG2,NSG1,GABRA1,GABRG1,GABRG2,JPH4,GAP43,DNER,MAP7D2,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,NEGR1,SHISA6,HSP90AA1,BRINP3,KCND2,STMN1,NEXMIF,NCAM1,NELL1,NELL2,NNAT,NOVA1,KSR2,OPCML,PDGFRA,SERPINI1,NXPH1,LRRN3,PLPPR1,RIT2,RORB,RTN1,SCN2A,SCN3A,ASIC4,TRIM67,LIMCH1,SNAP25,MYT1L,SST,SYT1,SYT5,KIAA1107,RALYL,CSMD1,RUNDC3B,TMEFF2,VSNL1,CELF4,REEP1,FSTL5,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 5.20E-52 2.65E-48 5.89E-50 5.37E-49 207 439 "ABR,RBM10,FMNL2,KIDINS220,CEP126,PCDH10,DOC2A,AMPH,ANK2,ANK3,SMIM29,PPFIA2,TNRC6C,TMEM108,CCDC181,ATP2B1,CDK5R1,SCAPER,CACNA1A,CACNA1B,CACNA1E,CAMK2B,BRSK2,RUNX1T1,FMNL3,INA,NEURL1,CDH8,DCLK1,ARHGAP33,DLGAP3,NRXN1,NRXN2,RCHY1,ACBD5,PREPL,CRMP1,TENM4,VCAN,NCAN,PDE4DIP,ERC2,RIMS2,PYGO1,KIAA0408,GPRASP1,SCRN1,BRINP1,DCC,CEP170,TMEM130,LYPD1,SNAP91,NTM,ARNT2,KBTBD11,DYNC1I1,DPP6,FIS1,EDIL3,YAF2,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EPB41L1,EPHB1,STX2,TUBB3,TAOK3,ATP5PD,NBEA,SORBS1,ARFGAP2,NSG2,NSG1,BRSK1,OGA,GABRB1,GABRB3,GAD1,JPH4,GAP43,ATP8A2,SRRM4,DNER,PCDH17,TOX3,GNAO1,PRRC2B,GPM6A,B4GALNT4,PCLO,CNTRL,STMN2,GRIA2,C1QL4,GRM5,KIF3A,RNF165,NEGR1,CPT1C,AGFG1,CELF5,ATCAY,LRRTM3,CDH20,KCND2,CREG2,KIF5C,KPNA5,L1CAM,LSAMP,ZFYVE27,MAP6,CHIC1,MEIS2,MKLN1,CD200,JAKMIP3,NEXMIF,NAP1L3,NCAM1,NELL1,NKX2-2,NNAT,NOVA1,OPCML,PCDH9,PDPK1,GNG2,TMOD2,RETREG1,PDZRN4,LRRN3,PKIA,PRKCB,SLC22A23,EML5,PTPRN2,ARID4A,RBBP6,BSDC1,REV3L,ZFHX4,ROBO1,ROBO2,RTN1,ZNF568,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SOX6,CASC3,PUF60,KIF21A,SLC1A2,SLC6A7,SLC8A1,CCDC88A,SHANK2,CPEB4,GKAP1,SMARCC2,MAPKBP1,SCN3B,MYT1L,KIF21B,SOX11,MYCBP2,ERC1,NPAS3,PHLDB1,SEPT3,STXBP1,SYP,SYT1,TAC1,ANKRD12,CAMTA1,CAMSAP2,KIAA1107,AGTPBP1,CLASP1,SYNE1,ARHGEF12,PUM2,ZFPM2,TMEM9,KCTD2,RBFOX2,CADM1,UBTF,UCHL1,CELF4,REEP1,STMN4,TMEM178A,RTN4,PAK5,CERS6,NETO2,SLC4A10,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 200 GSE76381_iPSMoleculeCountsPMLog2 3.80E-51 1.94E-47 4.22E-49 3.84E-48 277 694 "ACADM,ASIC1,ACLY,ABHD6,XKR4,FMNL2,TMEM132B,SLITRK1,ADCY6,TMCC3,KIDINS220,INTS2,TBC1D14,OSBPL8,ALCAM,PCDH10,ALK,SYT13,ANK2,ANK3,APBB1,APP,CPNE5,SLC7A14,ARHGAP5,CADPS,ZSCAN18,PCDHGB4,ASTN1,RNF182,B3GALT2,KIF1A,SEC11C,BMP7,BAIAP3,FOXK1,CALB1,CAST,RUNX1T1,LDB2,INA,SEPT7,LONRF2,CDC42,CDH10,MAGI1,CFL2,CHGA,CHGB,SOCS6,NRXN1,COG1,TMEM59L,MAP4K4,CNTN1,AKAP6,ZFP28,CRMP1,SLC32A1,TENM4,CNTNAP2,PLXNA4,PITPNM3,SDC3,CALY,KIAA0408,DCAF8,DAPK3,DCC,PITPNC1,DNAJC6,JAKMIP2,TMEM130,RHOBTB1,PLPPR4,SNAP91,SV2A,KBTBD11,GRIN3A,DNM1,SEZ6L2,TSPAN5,EFNB3,CELSR3,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,STARD3NL,PLEKHO1,EPB41L1,RCAN2,DMTN,EPHA5,SPEG,MRPL37,RTN3,CACNG2,FDFT1,FGF13,ACTL6B,HPCAL4,EVL,POMT1,NSG2,DACH2,NSG1,PNMA2,FUT9,B3GAT1,FYN,DKK3,GABRB3,JPH4,GAP43,DNER,GFRA1,PCDH17,C1QL1,BRD8,GLRB,TOX3,STARD3,MAP7D2,GNAL,GNAO1,GNG3,GNG4,GPT2,GPM6A,GPM6B,PCLO,STMN2,RAPGEF1,GRIA2,ATE1,KIF3A,AP4S1,RABL2A,CELF3,ACOT7,NEGR1,CELF5,HTR2A,ATCAY,IDH3A,ZNF546,TUBB2B,LRRTM3,JAK2,KCNC2,KCNN3,KIF5C,KLC1,MSANTD3-TMEFF1,LSAMP,MARK1,KCTD6,KITLG,AFDN,CD200,SCG3,HS6ST3,MYO5A,BEX5,FXYD6,NCAM1,NELL2,NRCAM,NRDC,NTRK3,KSR2,KCNK10,PAK3,PBX1,PCSK1,PDE4D,GNG2,TMOD2,SERPINI1,SNX10,LRP12,SEPT4,SLC36A4,FAT3,PPP2R2B,PKIA,NDUFS7,APTX,PXK,PTPRN,PLEKHB2,ZNF793,ATG16L1,SUSD4,ARID4A,BSDC1,RET,REV3L,ZFHX4,ROBO1,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,SH3GL2,NLGN1,ABLIM3,SLC1A2,URGCP,EPN2,WDR47,SLC6A1,SLC8A1,NAPB,CPEB4,OGDHL,SNAP25,SNCA,FAM126B,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,ZBTB43,LMO3,SRPK2,CLASP2,CAMTA2,SSTR2,SEPT3,STXBP1,NECAB1,VPS13A,SYP,SYT1,SYT4,KIAA0930,ARHGEF12,PCDHA7,AHCYL2,ATP13A2,RBFOX2,LRRC24,NEIL2,TUB,TUBB2A,TMEFF2,CADM1,UCHL1,DNAJC12,VGF,VLDLR,NPDC1,ZNF708,ATP6V0E2,NDRG4,CELF4,REEP1,FSTL5,SH3GLB2,PLPPR5,UPF3A,CADM2,RGMA,STMN4,SCG2,SLC17A6,RTN4,NETO2,AP3B2,ST8SIA2,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.97E-50 2.03E-46 4.31E-48 3.93E-47 179 356 "ASIC2,ASIC1,NDRG3,PNMA8B,PLEKHH1,BEND6,ZNF608,SYT13,AMPD2,ANK2,ANK3,SMIM29,APBB1,VAT1L,APP,ZSCAN18,DACT3,CADM3,ATP6V0A1,KIF1A,SEC11C,CDK5R1,CACNA1B,CAMK2B,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,MAGI1,DLGAP2,ADGRG1,CHGB,NRXN1,TMEM59L,CNTN1,PREPL,AKAP12,CRMP1,RIMS4,CALY,KIAA0408,FGFR1OP2,RIMS3,DCC,DNAJC6,JAKMIP2,TIAM2,CEP170,TMEM130,SNAP91,SV2A,NTM,DSCAM,EDIL3,SEZ6L2,ATL1,TENM1,ELAVL2,PLEKHA1,ELAVL3,ELAVL4,TMEM35A,RCAN2,EPHA5,NCALD,TUBB3,OLFM1,CAMSAP1,NPTN,KHDRBS3,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB3,JPH4,GAP43,DNER,GNAO1,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,ACOT7,CELF5,ATCAY,KIF5C,KLC1,LSAMP,MARK1,MGAT3,GIT1,SCG3,SAMD14,HS6ST3,MYO5A,TCEAL5,BEX5,FXYD6,NAP1L3,NCAM1,PCDH9,PCSK1,GNG2,TMOD2,SNX10,PPP2R2B,VSTM2L,PRKAB2,PKIA,PTPRN,PTPRO,IQSEC3,HUNK,RTN1,STX1B,CCDC112,ATXN1,SCN2A,SCN3A,SMPD3,PPP1R9A,FBXO11,SYBU,SLC8A1,SHANK2,NAPB,CXXC4,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,LMO3,CLASP2,MPRIP,SEPT3,STXBP1,PLCB1,SYT1,SYT4,SYT5,TAC1,TBL1X,RALYL,PCDHA7,ATP13A2,ASXL3,TUB,TUBB2A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,ZBTB38,REEP1,CADM2,PRDM2,STMN4,TUBA1A,SCG2,SLC17A6,FZD3,RTN4,CERS6,PIANP,NETO1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 200 GSE76381_ESMoleculeCountsPMLog2 4.59E-50 2.34E-46 4.88E-48 4.45E-47 279 709 "AXIN2,KIDINS220,ZNF608,DISP3,SYT13,OGT,ANK2,ANK3,APBA2,APLP1,TNRC6C,DACT3,KIF1A,CDK5R1,NAE1,SCAPER,GPC2,WASF1,CACNA2D1,CALB1,THSD7A,KALRN,BRSK2,RUNX1T1,CBLN1,INA,CBFA2T2,LONRF2,DCLK1,CDR1,UBE2L6,ADGRG1,NDST3,LHX2,NRXN1,SULT4A1,MAP4K4,AKAP6,MAGED1,ZNF521,IGDCC3,HS3ST5,CRMP1,CLIP3,VCAN,NCAN,CNTNAP2,GREB1,CTNND2,ST18,KIAA0408,TCAF1,RIMS3,SCRN1,DCC,DCTN1,HP1BP3,TMEM130,SV2A,FAM57B,ARRDC4,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,BSCL2,STARD3NL,ENO2,EPB41,EPHA5,EPHB1,STX2,RAB9B,ERBB4,NCALD,EFS,KATNAL1,NRN1,ACSL4,TUBB3,CORO2B,FGF13,UBE2E3,MEX3B,C1orf61,IP6K2,PCYOX1,EVL,PSD2,JKAMP,NBEA,UFM1,NSG2,GPR153,NSG1,DLL3,STAU2,B3GAT1,TPPP3,DKK3,GABRB3,GAP43,MTHFD2,C15orf41,SRRM4,DNER,GFRA1,PCDH17,SPIN1,GLUL,OS9,GNG3,GNG4,GPM6A,GPM6B,TMEM121B,CECR2,STMN2,GRIA2,C1QL4,GYG1,CELF3,UBE2QL1,KLF12,ACOT7,IGFBPL1,ATCAY,INSM1,OLFM3,KIF5C,KLC1,IPO5,L1CAM,MSANTD3-TMEFF1,LMO2,MAP4,MAP6,MEIS1,MEIS2,MEST,SCAMP5,AFDN,CD200,MRPL42,BLOC1S2,THYN1,SCG3,TAGLN3,MDGA1,MYBPC1,MYO5A,MYO6,BEX5,NCAM1,RCOR2,NEFM,NELL1,NEUROD1,NHLH1,NNAT,NUMA1,PAK3,PALM,PAX6,PCDH9,PCMT1,PCSK1,PRTG,PDE4D,PDPK1,GNG2,PFKFB4,OLA1,PFKP,GDAP1L1,CAMKV,PKM,SLC25A23,SCHIP1,NECAB2,POU3F2,DRAM2,TATDN3,LRRN3,NKAIN4,PKIA,MAPK8,NDUFS7,SLC22A23,PSMD13,PTCH1,PTPRG,NKAIN1,RALGDS,C1orf54,ARID4A,RGS10,ZFHX4,ROBO1,ROBO2,CCDC25,KIAA0895L,HUNK,RTN1,AMER2,SARS,SEMA6D,CSRNP3,SCN3A,HES6,TNFRSF19,SEC14L1,SCG5,SHMT2,SLC1A2,RUFY2,SLC6A8,SNAP25,SNCA,PDZRN3,SCN3B,MYT1L,KIF21B,SOX11,KDM3A,NMNAT2,BEX1,SPTAN1,NFASC,LMO3,CLASP2,SSTR2,EPB41L3,CEP68,GSE1,FGD4,SYT1,SYT4,TAC1,ANKRD12,PJA1,FAM208A,CNTN2,ADGRL3,KIAA0930,ZEB1,PUM2,FRYL,FAM200B,GPR161,BEX4,RBFOX2,FNDC5,SSBP2,TTC3,FAM155A,UCHL1,VAV2,CFAP298,ZIC1,ZIC2,ZIC3,FMN2,NDRG4,TCEAL7,CELF4,FSTL5,CADM2,SLC38A1,STMN4,SCG2,CIAPIN1,TMEM163,PCBP4,SLC17A6,FAM219B,CBLN2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 8.64E-50 4.41E-46 8.99E-48 8.19E-47 124 195 "KIDINS220,SYT13,ANK2,ANK3,APBB1,VAT1L,APP,ZSCAN18,KIF1A,SEC11C,CDK5R1,RUNX1T1,CBLN1,INA,SYNGR3,SEPT7,LONRF2,CDC42,DCLK1,CHGB,NRXN1,TMEM59L,CNTN1,PREPL,CRMP1,CTNND2,KIAA0408,RIMS3,DNAJC6,SNAP91,SV2A,SEZ6L2,OPTN,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,OLFM1,HPCAL4,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRG2,GAP43,DNER,GNAO1,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,CELF5,ATCAY,KIF5C,MSANTD3-TMEFF1,LSAMP,MARK1,SCG3,HS6ST3,MYO5A,BEX5,FXYD6,NCAM1,PAK3,PCSK1,GNG2,TMOD2,PPP2R2B,VSTM2L,PRKACB,PKIA,PTPRN,PTPRO,RAB3A,PNMA8A,RTN1,CSRNP3,ATXN1,SCN2A,SCN3A,SCG5,WDR47,NAPB,SNAP25,SNCA,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,SEPT3,STXBP1,SYP,SYT1,SYT4,PCDHA7,ATP13A2,FBXL16,RBFOX2,TUBB2A,UCHL1,DNAJC12,VGF,NDRG4,CELF4,REEP1,DPYSL5,CADM2,STMN4,SCG2,RTN4,CERS6,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.51E-49 7.69E-46 1.54E-47 1.40E-46 181 365 "ASIC1,NDRG3,ZNF608,SYT13,ANK2,ANK3,SMIM29,APBB1,VAT1L,APP,CDK13,ZSCAN18,DACT3,CADM3,ATP6V0A1,KIF1A,SEC11C,DCAF5,CDK5R1,CAMK2B,SPAG9,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,MAGI1,ADGRG1,CHGB,CHN1,CHN2,NRXN1,TMEM59L,CNTN1,RCHY1,PREPL,AKAP12,CRMP1,CS,RIMS4,CALY,KIAA0408,RIMS3,DCC,DNAJC6,JAKMIP2,CEP170,TMEM130,SNAP91,SV2A,NTM,DSCAM,EDIL3,SEZ6L2,ATL1,TENM1,ELAVL2,PLEKHA1,ELAVL3,ELAVL4,TMEM35A,DCTN4,RCAN2,EPHA5,NCALD,ADGRV1,TUBB3,OLFM1,CAMSAP1,MEX3B,IP6K2,NPTN,KHDRBS3,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB3,JPH4,GAP43,DNER,GLRB,GNAO1,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,ACOT7,CELF5,ATCAY,KIF5C,KLC1,LSAMP,MARK1,GIT1,SCG3,HS6ST3,MYO5A,TCEAL5,BEX5,FXYD6,NAP1L3,NCAM1,PCDH9,PCSK1,GNG2,TMOD2,SNX10,PPP2R2B,VSTM2L,PRKAB2,PKIA,PTPRN,PTPRO,IQSEC3,RPL15,HUNK,RTN1,CCDC112,ATXN1,SCN2A,SCN3A,SMPD3,PPP1R9A,FBXO11,R3HDM2,CCDC92,SYBU,SLC8A1,SHANK2,NAPB,CXXC4,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,ZNF423,BEX1,LMO3,CLASP2,MPRIP,SEPT3,STXBP1,PLCB1,SYT1,SYT4,SYT5,RALYL,PCDHA7,ATP13A2,CBX5,ASXL3,KAT6B,TUB,TUBB2A,UBE3A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,ZBTB38,REEP1,CADM2,PRDM2,STMN4,SCG2,RTN4,CERS6,VANGL2,PIANP" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 2.65E-49 1.35E-45 2.65E-47 2.42E-46 161 303 "KIDINS220,ZNF608,SYT13,ANK2,ANK3,APLP1,TNRC6C,KIF1A,CDK5R1,SCAPER,GPC2,CALB1,THSD7A,KALRN,RUNX1T1,CBLN1,INA,LONRF2,DCLK1,CDR1,LHX2,NRXN1,AKAP6,MAGED1,ZNF521,CRMP1,VCAN,CNTNAP2,CTNND2,KIAA0408,TCAF1,RIMS3,SCRN1,DCC,DCTN1,TMEM130,SV2A,FAM57B,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,ENO2,EPB41,RAB9B,NCALD,KATNAL1,NRN1,TUBB3,FGF13,IP6K2,EVL,PSD2,NBEA,NSG2,GPR153,NSG1,DLL3,STAU2,DKK3,GABRB3,GAP43,SRRM4,DNER,PCDH17,SPIN1,GNG3,GPM6A,STMN2,GRIA2,CELF3,KLF12,IGFBPL1,ATCAY,INSM1,OLFM3,KIF5C,KLC1,L1CAM,MSANTD3-TMEFF1,MAP4,MAP6,MEIS2,CD200,SCG3,TAGLN3,MDGA1,BEX5,NCAM1,NEFM,NHLH1,NNAT,PAK3,PAX6,PCDH9,PCMT1,PDE4D,PDPK1,GNG2,PFKP,GDAP1L1,PKM,NECAB2,POU3F2,LRRN3,PKIA,MAPK8,RALGDS,ZFHX4,ROBO1,ROBO2,KIAA0895L,RTN1,AMER2,CSRNP3,SCN3A,SCG5,SLC1A2,SNAP25,SCN3B,MYT1L,KIF21B,SOX11,NMNAT2,BEX1,SPTAN1,NFASC,LMO3,CLASP2,GSE1,SYT1,SYT4,TAC1,ANKRD12,PJA1,CNTN2,ADGRL3,ZEB1,FRYL,GPR161,BEX4,RBFOX2,FNDC5,TTC3,FAM155A,UCHL1,ZIC1,ZIC2,NDRG4,TCEAL7,CELF4,FSTL5,CADM2,SLC38A1,STMN4,SCG2,TMEM163,PCBP4,SLC17A6,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.44E-49 1.75E-45 3.31E-47 3.01E-46 123 194 "DPF1,ABR,KIDINS220,PCDH10,ANK2,PPFIA2,ARRB1,DACT3,ATP6V0A1,CDK5R1,CACNA1A,CALB1,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,CHGB,NRXN1,NRXN2,TMEM59L,CNTN1,CRMP1,CSNK1E,ERC2,RIMS2,KIAA0408,SPOCK2,BRINP1,DNAJC6,SNAP91,NTM,ARNT2,EEF1A2,OPTN,PLXNC1,ELAVL2,ELAVL3,TMEM35A,SEZ6,TUBB3,TUBB4A,TAOK3,FGF13,HPCAL4,EVL,PSD2,NPTN,NSG2,NSG1,PNMA2,SARAF,GABRG2,JPH4,GAP43,SRRM4,PCSK1N,GNAO1,GNG3,GPM6A,B4GALNT4,PCLO,STMN2,GRIA1,GRIA2,GRIA4,GRIK2,ACOT7,NEGR1,ATCAY,ICA1,KCNK3,KIF5C,KLC1,L1CAM,MSANTD3-TMEFF1,MAP4,CD200,BEX5,FXYD6,NAP1L3,NCAM1,NNAT,PCDH9,GNG2,TMOD2,SERPINI1,PPP2R2B,PRKACB,PKIA,PTPRD,ROBO2,BAALC,RTN1,SCN2A,SCN3A,SCG5,NAPB,SMARCD3,SNCA,SCN3B,MYCBP2,ERC1,BEX1,SEPT3,SYT1,TAC1,MCF2L,TMEM178B,RIMBP2,RUNDC3B,TUBB2A,CADM1,UCHL1,DNAJC12,PLPPR2,VSNL1,CELF4,REEP1,PLPPR5,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 3.44E-49 1.75E-45 3.31E-47 3.01E-46 123 194 "DPF1,ABR,KIDINS220,PCDH10,ANK2,PPFIA2,ARRB1,DACT3,ATP6V0A1,CDK5R1,CACNA1A,CALB1,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,CHGB,NRXN1,NRXN2,TMEM59L,CNTN1,CRMP1,CSNK1E,ERC2,RIMS2,KIAA0408,SPOCK2,BRINP1,DNAJC6,SNAP91,NTM,ARNT2,EEF1A2,OPTN,PLXNC1,ELAVL2,ELAVL3,TMEM35A,SEZ6,TUBB3,TUBB4A,TAOK3,FGF13,HPCAL4,EVL,PSD2,NPTN,NSG2,NSG1,PNMA2,SARAF,GABRG2,JPH4,GAP43,SRRM4,PCSK1N,GNAO1,GNG3,GPM6A,B4GALNT4,PCLO,STMN2,GRIA1,GRIA2,GRIA4,GRIK2,ACOT7,NEGR1,ATCAY,ICA1,KCNK3,KIF5C,KLC1,L1CAM,MSANTD3-TMEFF1,MAP4,CD200,BEX5,FXYD6,NAP1L3,NCAM1,NNAT,PCDH9,GNG2,TMOD2,SERPINI1,PPP2R2B,PRKACB,PKIA,PTPRD,ROBO2,BAALC,RTN1,SCN2A,SCN3A,SCG5,NAPB,SMARCD3,SNCA,SCN3B,MYCBP2,ERC1,BEX1,SEPT3,SYT1,TAC1,MCF2L,TMEM178B,RIMBP2,RUNDC3B,TUBB2A,CADM1,UCHL1,DNAJC12,PLPPR2,VSNL1,CELF4,REEP1,PLPPR5,STMN4,SCG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 7.93E-49 4.04E-45 7.49E-47 6.82E-46 219 497 "TTYH1,FMNL2,KLHL32,SLITRK1,PLEKHH1,PTCHD1,EPB41L5,PHYHD1,SHTN1,ASCL1,ASTN1,ATP2B2,KIF1A,CARMIL3,FGF17,PROM1,DIRAS1,HAP1,CAMK2A,INA,CDK11B,CDC25B,CDH2,MAGI1,ADGRG1,SRSF11,CBARP,JAM2,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN2,IQCK,COL4A5,IGDCC3,NECTIN3,SLC35F1,NCAN,CNTNAP2,SLITRK5,CTNND2,RIMS2,ST18,KATNAL2,SCRN1,DCC,JAKMIP2,SRGAP3,KBTBD11,DLX1,RAB39B,DMD,DTNA,MAMLD1,ST8SIA3,FSD1L,ELAVL2,ELAVL3,ELAVL4,EMX2,OLIG2,EPHB1,SLC43A2,APC2,RRAGB,ADGRV1,REEP2,CLVS1,FABP7,ZIC4,TUBB3,TUBB4A,SPSB4,FGFR3,FOXG1,AFF2,DLL3,FUT9,B3GAT1,PHYHIPL,ILDR2,GAD1,SRRM4,PPARGC1A,RUNDC3A,NTNG2,GLDC,TOX3,PCDH11X,MAP7D2,DCLK2,GNG3,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,RNF165,SOX21,RNFT2,CELF3,TOX2,FRMD5,BACH2,IGFBPL1,USP51,CELF5,ATCAY,SHISAL1,ZIC5,IGSF1,HES5,BRINP3,KCNH2,KTN1,MAP2,SHC3,PPM1L,CPNE9,SCG3,TAGLN3,LINC00672,MYT1,NASP,NEFM,NELL2,NNAT,NOVA1,SLC11A2,NRCAM,NTRK2,GPR137C,PAK3,PRTG,PGAM2,SEMA5B,GPSM2,SLC25A23,PLXNB1,MAGEL2,FAT3,MAPK10,DIRAS2,GDPD1,RELN,ELOVL2,EML5,RAD51D,FAM184A,ARID4A,FEZF2,GAL3ST4,RFX4,RTN1,CCDC112,SALL1,LRRTM4,LINC00461,SOX6,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,ARX,FHOD3,CCDC92,SLC1A2,CXXC4,MAST1,SNAP25,TMCC1,SOX2,SOX5,SOX11,LHFPL4,NPAS3,GSE1,ACSBG1,SYT11,FGD4,SYNE2,RHBDL3,SYN1,SYP,ASTN2,SEMA4A,WWC1,WSCD1,ACSL6,CUX2,TCF7L2,TRIM2,WASHC4,PSD3,FRYL,AHCYL2,CCDC173,NR2E1,PRMT8,CA14,TUB,SLAIN1,MGAT5B,ZIC1,ZIC2,ZIC3,FMN2,ZBTB16,DPYSL5,STMN4,GAL3ST3,WNK2,FZD3,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.50E-49 4.85E-45 8.81E-47 8.03E-46 118 182 "KIDINS220,PCDH10,ANK2,ANK3,SMIM29,PPFIA2,TNRC6C,CDK5R1,CACNA1A,CACNA1E,CAMK2B,RUNX1T1,INA,DCLK1,NRXN1,NRXN2,PREPL,CRMP1,VCAN,NCAN,PDE4DIP,ERC2,RIMS2,KIAA0408,GPRASP1,CEP170,SNAP91,NTM,ARNT2,DPP6,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EPB41L1,EPHB1,TUBB3,TAOK3,NBEA,NSG2,NSG1,GABRB3,GAD1,JPH4,GAP43,SRRM4,DNER,PCDH17,GNAO1,PRRC2B,GPM6A,B4GALNT4,PCLO,STMN2,GRIA2,GRM5,KIF3A,RNF165,NEGR1,CELF5,ATCAY,KIF5C,L1CAM,LSAMP,MAP6,NEXMIF,NAP1L3,NCAM1,NNAT,NOVA1,PCDH9,GNG2,TMOD2,PDZRN4,LRRN3,PKIA,PRKCB,ARID4A,REV3L,ROBO1,ROBO2,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,KIF21A,SLC1A2,CCDC88A,SHANK2,CPEB4,SMARCC2,SCN3B,MYT1L,KIF21B,SOX11,MYCBP2,NPAS3,SEPT3,STXBP1,SYT1,TAC1,ANKRD12,CAMTA1,CAMSAP2,KIAA1107,ARHGEF12,RBFOX2,CADM1,UCHL1,CELF4,REEP1,STMN4,PAK5,CERS6,SLC4A10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 200 GSE76381_iPSMoleculeCountsPMLog2 5.57E-48 2.84E-44 5.08E-46 4.63E-45 223 516 "RALGAPA1,RBM10,ACTN1,GPRIN1,SORCS1,PTCHD1,KIDINS220,SEMA6A,ALCAM,PCDH10,SYT13,ANK2,ANK3,SMIM29,APBB1,EPB41L5,VAT1L,APP,PLA2G4C,ZSCAN18,KIF1A,ADGRB2,SEC11C,BCL2L2,CDK5R1,AP1M1,RUNX1T1,CBLN1,LDB2,INA,SYNGR3,SEPT7,LONRF2,CDC42,DCLK1,CDH18,CHGA,CHGB,CNOT8,RAB33A,NRXN1,CLU,TMEM59L,CNTN1,SLC35F1,PREPL,CRMP1,NCOR1,SOCS5,CTNND2,KIAA0408,DOCK4,TOX,KIAA0513,RIMS3,BRINP1,DBN1,DNAJC6,FBXL5,RUSC2,COPS7A,LYPD1,SNAP91,SV2A,NTM,CD99L2,CPEB2,EBF1,SEZ6L2,OPTN,PLXNC1,TENM1,ELAVL2,PLEKHA1,ELAVL3,BSCL2,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,OLFM1,FHL1,SUCO,UBE2E3,HPCAL4,STAMBP,ATP2C1,NSG2,NSG1,PNMA2,SARAF,OGA,FYN,DKK3,GABRG2,JPH4,GAP43,DNER,TOX3,GNAO1,GNG4,GP1BB,GPM6A,CCDC184,EML4,PCLO,STMN2,GRIA2,PTPRT,KIF3A,RNFT2,CELF3,UBE2QL1,IGSF21,NEGR1,CELF5,ATCAY,KCNB1,KIF5C,MSANTD3-TMEFF1,LSAMP,MARK1,LRP1B,CD200,SCG3,MTR,HS6ST3,MYO5A,MYO9A,BEX5,HNRNPM,FXYD6,NASP,NCAM1,NEFM,NELL2,NOVA1,SMIM11A,NTRK2,OPCML,PAK3,PCDH9,PCSK1,PCSK2,GNG2,TMOD2,PLCL1,EPN1,FAT3,PPM1B,PPP2R2B,VSTM2L,PRKACB,PKIA,PROX1,PTPRE,PTPRN,PTPRN2,PTPRO,RAB3A,RAD52,RIT2,PNMA8A,FBXW7,KIAA0895L,RTN1,CSRNP3,ATXN1,SCN2A,SCN3A,ELMOD1,ASRGL1,SCG5,NLGN1,WDR47,NAPB,CXXC4,RCOR3,SNAP25,SNCA,KIF13A,FAM126B,SCN3B,FAM219A,WDTC1,KIF21B,SOX11,NMNAT2,MYCBP2,PEG10,BEX1,IQSEC2,EPB41L3,SEPT3,STXBP1,SYP,SYT1,SYT4,EHBP1,PCDHA7,ATP13A2,FBXL16,RBFOX2,TUBB2A,UCHL1,DNAJC12,MTCH1,PLPPR2,VGF,ZNF540,NDRG4,TCEAL7,CELF4,REEP1,DPYSL5,CADM2,RGMA,STMN4,SCG2,RTN4,CERS6,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 5.86E-48 2.99E-44 5.25E-46 4.78E-45 176 356 "RALGAPA1,RBM10,PTCHD1,KIDINS220,ALCAM,PCDH10,SYT13,ANK2,ANK3,SMIM29,APBB1,EPB41L5,VAT1L,APP,ZSCAN18,KIF1A,SEC11C,CDK5R1,AP1M1,RUNX1T1,CBLN1,LDB2,INA,SYNGR3,SEPT7,LONRF2,CDC42,DCLK1,CHGB,CNOT8,RAB33A,NRXN1,TMEM59L,CNTN1,SLC35F1,PREPL,CRMP1,NCOR1,CTNND2,KIAA0408,TOX,KIAA0513,RIMS3,DBN1,DNAJC6,RUSC2,SNAP91,SV2A,NTM,SEZ6L2,OPTN,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,OLFM1,FHL1,SUCO,UBE2E3,HPCAL4,STAMBP,NSG2,NSG1,PNMA2,SARAF,OGA,FYN,DKK3,GABRG2,JPH4,GAP43,DNER,TOX3,GNAO1,GNG4,GP1BB,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,RNFT2,CELF3,UBE2QL1,NEGR1,CELF5,ATCAY,KIF5C,MSANTD3-TMEFF1,LSAMP,MARK1,LRP1B,CD200,SCG3,MTR,HS6ST3,MYO5A,BEX5,HNRNPM,FXYD6,NASP,NCAM1,NELL2,NOVA1,PAK3,PCDH9,PCSK1,GNG2,TMOD2,PLCL1,FAT3,PPP2R2B,VSTM2L,PRKACB,PKIA,PTPRN,PTPRO,RAB3A,RAD52,PNMA8A,FBXW7,KIAA0895L,RTN1,CSRNP3,ATXN1,SCN2A,SCN3A,SCG5,WDR47,NAPB,CXXC4,RCOR3,SNAP25,SNCA,KIF13A,FAM126B,SCN3B,WDTC1,KIF21B,SOX11,NMNAT2,MYCBP2,PEG10,BEX1,SEPT3,STXBP1,SYP,SYT1,SYT4,EHBP1,PCDHA7,ATP13A2,FBXL16,RBFOX2,TUBB2A,UCHL1,DNAJC12,MTCH1,VGF,NDRG4,CELF4,REEP1,DPYSL5,CADM2,STMN4,SCG2,RTN4,CERS6,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.03E-47 5.23E-44 9.02E-46 8.22E-45 345 989 "DPF1,CPNE2,TTYH1,ABCF1,SYN3,ACLY,NCKAP5,ACTN2,KLHL32,SLITRK1,ADCYAP1R1,KIAA1211,KIAA1324,EPB41L5,APLP1,PHYHD1,ARRB2,ASCL1,ZBTB10,ASTN1,CCDC181,ATP1A3,ATP2B1,ATP2B2,ATP6V1G2,KIF1A,ADAM23,ADGRB3,BLM,ZNF599,PROM1,ARHGEF7,CACNA1A,CACNA2D1,THSD7A,DIRAS1,HAP1,PTBP2,CANX,MAP7,INA,SLC16A4,CDK11B,LRBA,CDC25B,LONRF2,CDH2,CDH8,ARHGAP33,MAGI1,ADGRG1,SRSF11,JAM2,SLIT2,LHX2,CLCN3,KIAA1549L,NRXN2,COG1,C4orf33,QKI,HECTD1,NIPBL,IQCK,COL4A5,SLC4A7,SLC4A8,IGDCC3,NECTIN3,SLC35F1,CRMP1,NCOR1,CLIP3,PLCH2,NCAN,CNTNAP2,FAM169A,SLITRK5,ERC2,PHF14,CTNND2,RIMS2,ST18,KATNAL2,TCAF1,TOX,TBC1D5,KIAA0586,DGKB,SCRN1,AIF1L,DCC,JAKMIP2,DDX46,SMG7,SRGAP3,RAB39B,DMD,CASP8AP2,MAMLD1,E2F5,KLHL5,FSD1L,EFNA3,PLXNC1,ELAVL2,ELAVL3,ELAVL4,EMX2,OLIG2,EPHA5,APC2,RTN3,RRAGB,ADGRV1,REEP2,CLVS1,NSRP1,FABP7,ACSL4,ZIC4,TUBB4A,CORO2B,ATP8A1,SPSB4,FGF12,FGFR3,FHL1,FOXG1,ZNF605,NSG2,DLL3,FUT9,B3GAT1,ADGRA1,PHYHIPL,GABRB3,ILDR2,SALL3,HIGD1B,TMEM8B,C15orf41,SRRM4,KIAA1841,PPARGC1A,TCERG1,GLDC,DBF4,TOX3,PCDH11X,MAP7D2,GNAO1,GNG3,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,RFFL,GRIK2,GRIK4,CIT,KIF3A,RNF165,MFSD2A,RABL2A,SOX21,RNFT2,GUCY1B1,CELF3,TOX2,FRMD5,DDX19B,IGFBPL1,HPCA,USP51,HSP90AA1,SMAP1,ATCAY,SHISAL1,ZIC5,HES5,INSM1,TUBB2B,LRRTM1,SLC35G1,KCNN3,KIF2A,KIF5C,KIT,KTN1,HECTD2,LSAMP,MAP2,TM6SF1,SHC3,PPM1L,BCO1,SCG3,TAGLN3,RSPO2,MYO5A,MYT1,NASP,NEFM,NEK1,NELL2,NOVA1,NRCAM,SMIM11A,NTRK2,ODF2,GPR137C,PAK3,PAX6,PRTG,FAM98B,SEMA5B,PLP1,SLC25A23,MTRF1L,TRHDE,MAGEL2,FAT3,POU3F4,IRX1,PKIA,MAPK10,DIRAS2,PROX1,GDPD1,MASP1,SLC22A23,LAMA1,GDPD2,MDGA2,ANKHD1,ELOVL2,EML5,PTPRZ1,STRC,CEP97,RAD51D,FAM184A,ARID4A,FEZF2,RBBP6,REV3L,RFX4,GSTCD,CCDC25,FBXW7,CLIP1,RTN1,RXRA,SAFB,SALL1,LINC00461,TNFRSF19,ZFP2,SOX6,HSPA4L,SCG5,KIF21A,PPM1E,ARX,FHOD3,NLGN1,ANKRD6,SLC1A2,PEX26,WDR47,PKNOX2,CCDC88A,SLCO1A2,GKAP1,SMARCA4,MAST1,SNAP25,SOX2,SPATA7,BDP1,SOX11,NPAS3,LMO3,PBLD,LARP4,NEK4,TTBK2,AJAP1,SYT11,FGD4,SYNE2,VPS13A,C3orf70,SYN1,MTCL1,ROBO3,WWC1,WSCD1,ACSL6,CUX2,TCF7L2,WASHC4,FRYL,AHCYL2,CCDC173,DICER1,NR2E1,BEX4,PRMT8,STXBP4,CADM1,UCHL1,SLAIN1,FLRT1,FAM181B,MGAT5B,RBFOX3,WNT7A,ZIC1,ZIC2,ZIC3,ZNF23,TRIM9,ZFP41,FMN2,ZBTB16,REEP1,ZNF184,DPYSL5,LRP8,SLC38A1,STMN4,STOX2,GAL3ST3,NAV2,TMEM163,WNK2,FZD3,HNRNPA3,NETO2,PRRT4,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.28E-47 6.52E-44 1.11E-45 1.01E-44 196 424 "SLITRK1,ADCY8,SORCS1,PCDH10,DPP10,ANK2,PPFIA2,VAT1L,SLC7A14,CADPS,ASCL1,ASPH,ASTN1,INSYN2B,RNF182,ADAM23,ADGRB3,ARHGEF7,LDLRAD4,CACNA1B,CH25H,BRSK2,RUNX1T1,CBLN1,CDH10,DCLK1,LGI1,CDO1,CRLF1,CHGB,SYNPR,CNR1,CNTN1,AKAP6,COL9A1,COL9A3,MYRIP,ZNF521,FAM171B,CREM,CRMP1,CRYM,FEZ1,NRSN1,RIMS2,ST18,TOX,SCRN1,BRINP1,PITPNC1,DNAJC6,JAKMIP2,MAGI2,SNAP91,CHRDL1,DLX1,GRIN3A,RAB39B,CALN1,DRD1,ABCC9,EBF1,EDIL3,ST8SIA3,EDN3,EDNRB,TENM1,ELAVL2,ELAVL4,PCOLCE2,EPHA5,EYA1,CLVS1,WAC,FABP7,TMEM132C,EFEMP1,FGF13,UBE2E3,FOXF2,SGIP1,NBEA,DACH2,MEGF10,GABRA1,GABRA4,CHL1,GABRB3,GAP43,SRRM4,DNER,GFRA1,GFRA2,PPARGC1A,GLRB,PCDH11X,RAB40B,GPR17,GPR22,STMN2,GRM3,GRM7,FAM19A2,WIF1,HAS2,UBE2QL1,NEGR1,AGFG1,IFI16,INSM1,LRRTM3,KCNA1,KCNK2,KCNQ2,KIF5A,KIF5C,SYTL4,MAP4,MAPT,IL17D,RSPO2,MYH3,NAP1L2,NCAM2,NDP,NEFM,NTRK2,CLDN11,CNTN3,PDE4B,PIRT,SLC10A4,GPR85,DUSP26,NLGN3,SERPINI1,NALCN,PLP1,TRHDE,PRRX1,EPB41L4B,MAPK10,PRPH,PTPRZ1,SLC6A15,ZMAT4,RET,FIGN,RGS4,TTLL7,ZFHX4,ROBO1,RPS20,RTN1,RYR3,SALL1,CSRNP3,SCN3A,FAM19A1,NTNG1,ANKRD6,ZNF365,SLC14A1,NAPB,CXXC4,SNAP25,UNC80,SCN3B,SOX2,NPAS3,C11orf87,ELOVL4,KLHL7,SYT11,SYN2,SYT4,TAC1,UNC5D,ACSL6,PCDHB15,PCDHB10,PCDHB7,PCDHB3,HIF3A,HHIP,TIMP4,ASXL3,SYNPO2,TMEFF2,RPRM,AGMO,FMN2,FSTL5,LRP8,STMN4,FAM13C" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.71E-47 1.38E-43 2.31E-45 2.10E-44 121 194 "SYT13,ANK2,ANK3,SMIM29,APBB1,VAT1L,APP,DACT3,CADM3,ATP6V0A1,KIF1A,SEC11C,CDK5R1,CAMK2B,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,CHGB,NRXN1,TMEM59L,CNTN1,PREPL,AKAP12,CRMP1,RIMS4,CALY,KIAA0408,RIMS3,DNAJC6,JAKMIP2,CEP170,TMEM130,SNAP91,SV2A,SEZ6L2,ATL1,TENM1,ELAVL2,PLEKHA1,ELAVL3,TMEM35A,RCAN2,EPHA5,NCALD,OLFM1,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB3,JPH4,GAP43,DNER,GNAO1,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,ACOT7,CELF5,ATCAY,KIF5C,KLC1,LSAMP,MARK1,GIT1,SCG3,HS6ST3,MYO5A,TCEAL5,BEX5,FXYD6,NCAM1,PCSK1,GNG2,TMOD2,PPP2R2B,PKIA,PTPRN,PTPRO,RTN1,ATXN1,SCN2A,SCN3A,NAPB,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,LMO3,CLASP2,SEPT3,STXBP1,SYT1,SYT4,PCDHA7,ATP13A2,TUBB2A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,STMN4,SCG2,RTN4,CERS6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE76381_iPSMoleculeCountsPMLog2 2.79E-47 1.42E-43 2.34E-45 2.13E-44 199 436 "ASIC2,ASIC1,NDRG3,PNMA8B,PLEKHH1,BEND6,ZNF608,SYT13,AMPD2,ANK2,ANK3,SMIM29,APBB1,VAT1L,APP,CDK13,ZSCAN18,DACT3,CADM3,ATP6V0A1,KIF1A,SEC11C,DCAF5,CDK5R1,CACNA1B,CAMK2B,SPAG9,RUNX1T1,INA,SYNGR3,SEPT7,LONRF2,DCLK1,MAGI1,DLGAP2,ADGRG1,CHGB,CHN1,CHN2,NRXN1,TMEM59L,CNTN1,RCHY1,PREPL,AKAP12,CRMP1,CS,RIMS4,CALY,KIAA0408,FGFR1OP2,RIMS3,DCC,DNAJC6,JAKMIP2,TIAM2,CEP170,TMEM130,SNAP91,SV2A,NTM,DSCAM,EDIL3,SEZ6L2,ATL1,TENM1,ELAVL2,PLEKHA1,ELAVL3,ELAVL4,TMEM35A,DCTN4,RCAN2,EPHA5,NCALD,ADGRV1,TUBB3,OLFM1,CAMSAP1,MEX3B,IP6K2,NPTN,KHDRBS3,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB3,JPH4,GAP43,DNER,GLRB,GNAO1,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,ACOT7,CELF5,ATCAY,KIF5C,KLC1,LSAMP,MARK1,MGAT3,GIT1,SCG3,SAMD14,HS6ST3,MYO5A,TCEAL5,BEX5,FXYD6,NAP1L3,NCAM1,PCDH9,PCSK1,GNG2,TMOD2,SNX10,PPP2R2B,VSTM2L,PRKAB2,PKIA,PTPRN,PTPRO,IQSEC3,RPL15,HUNK,RTN1,STX1B,CCDC112,ATXN1,SCN2A,SCN3A,SMPD3,PPP1R9A,FBXO11,R3HDM2,CCDC92,SYBU,SLC8A1,SHANK2,NAPB,CXXC4,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,ZNF423,BEX1,LMO3,CLASP2,MPRIP,SEPT3,STXBP1,PLCB1,SYT1,SYT4,SYT5,TAC1,TBL1X,RALYL,PCDHA7,ATP13A2,CBX5,ASXL3,KAT6B,TUB,TUBB2A,UBE3A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,ZBTB38,REEP1,CADM2,PRDM2,STMN4,TUBA1A,SCG2,SLC17A6,FZD3,RTN4,CERS6,VANGL2,PIANP,NETO1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 4.02E-47 2.05E-43 3.31E-45 3.01E-44 212 482 "DPF1,TTYH1,NCKAP5,SLITRK1,ADCYAP1R1,PLEKHH1,KIAA1211,PCDH10,EPB41L5,SHTN1,ASCL1,PTCH2,ATP1A3,ATP2B2,KIF1A,PROM1,DDR1,DIRAS1,HAP1,CBLN1,INA,CDH2,CDH8,ARHGAP33,ADGRG1,SRSF11,JAM2,LHX2,NRXN3,NRXN2,QKI,IGDCC3,SLC35F1,CRMP1,CSNK1E,NCAN,CNTNAP2,SLITRK5,CTNND2,RIMS2,ST18,SCRN1,DCC,JAKMIP2,ELMO1,SRGAP3,KBTBD11,DLX1,RAB39B,DTNA,MAMLD1,ST8SIA3,EDNRB,FSD1L,PLXNC1,ELAVL2,ELAVL3,ELAVL4,OLIG2,SEZ6,EPHB1,APC2,PIPOX,ADGRV1,REEP2,CLVS1,FABP7,ZIC4,TUBB3,TUBB4A,FOXG1,FOXM1,AFF2,DPYSL4,POMT1,NSG2,DLL3,FUT9,B3GAT1,PHYHIPL,GABRB3,ILDR2,GAD1,GAD2,SRRM4,ACSS1,KIAA1841,PPARGC1A,RUNDC3A,GLDC,TOX3,MAP7D2,DCLK2,GNG3,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,GRIK3,RNF165,MFSD2A,SOX21,FAM222A,CELF3,TOX2,FRMD5,IGFBPL1,USP51,CELF5,ATCAY,SHISAL1,HES5,INSM1,TUBB2B,KCNH2,KIF5C,LRRC4B,LSAMP,MAP2,MARK1,MBP,SHC3,PPM1L,MSI1,SCG3,TAGLN3,MYCN,MYT1,NELL2,NNAT,NOVA1,NRCAM,GPR137C,PAK3,TMOD2,GDAP1L1,SEMA5B,POU3F4,MAPK10,PROX1,GDPD1,ELOVL2,EML5,PTPRZ1,RFX4,SOX8,RTN1,SALL1,MAPK12,LINC00461,ZFP2,SOX6,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,ARX,SLC1A2,CXXC4,MAST1,SNAP25,SNRPN,SOX2,SOX11,LHFPL4,KIF1B,NPAS3,GSE1,ACSBG1,SYT11,SYNE2,SYN1,SYP,TACC1,ROBO3,MCF2L,TMEM178B,WSCD1,ACSL6,CUX2,WASHC4,CLASP1,FRYL,HEY1,NR2E1,CA14,TUB,UCHL1,SLAIN1,FAM181B,MGAT5B,RBFOX3,WNT7A,ZIC1,ZIC3,ZFP41,CELF4,REEP1,TMEM198,DPYSL5,MEIS3,STMN4,STOX2,PCBP4,WNK2,FZD3,RSPRY1,SPATA13" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.13E-47 2.11E-43 3.35E-45 3.05E-44 127 211 "CSMD3,ADCYAP1R1,SORCS1,PCDH10,UNC79,ANK2,APBA2,VAT1L,SLC7A14,CADPS,CADM3,ATP6V0A1,KIF1A,ADAM23,ADGRB3,NRP2,INA,LONRF2,DCLK1,CHGB,RAB3C,RAB33A,NRXN1,PICK1,FAM171B,CRMP1,FEZ1,PLXNA4,ERC2,NRSN1,RIMS2,SCRN1,DNAJC6,JAKMIP2,SNAP91,SPOCK3,DLG2,EBF1,EDNRB,FRY,ELAVL2,ELAVL4,DENND4A,NCALD,CEND1,EYA1,CLVS1,FABP7,TUBB3,ATP8A1,CHST15,FDFT1,FGF13,SGIP1,NSG2,TPPP3,GABRB3,GAP43,SYT17,IGSF5,GFRA1,GFRA2,GLRB,GNAO1,GPR19,STMN2,GRIA2,GRIK2,ARHGAP36,HMGCR,DISP2,LIX1,TUBB2B,KIF5A,KIF5C,KIT,L1CAM,SYTL4,MAOB,MAP6,ADAM22,SCG3,MYT1,NCAM1,NEFM,NELL2,NOVA1,NRCAM,PCDH9,SLC10A4,TMOD2,PFKP,SERPINE2,NALCN,PPP2R2B,MAPK10,PROX1,STK32A,EML5,ENOX1,ZMAT4,RET,RGS4,ARMH4,RTN1,RYR3,SCN2A,SCN3A,SCG5,SH3GL3,SNAP25,SNRPN,SCN3B,NMNAT2,EPB41L3,SEPT3,SYT11,SYP,SYT1,SYT4,AGTPBP1,CUX2,TUBB2A,TMEFF2,CADM1,STMN4,TUBA1A" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k1_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.58E-47 2.84E-43 4.44E-45 4.05E-44 129 217 "CSMD3,SLITRK1,RNF157,DPP10,ANK2,VAT1L,SLC7A14,CADPS,ASCL1,ASPH,ASTN1,NOL4,ADGRB3,ARHGEF7,CACNA1B,VSTM2A,BRSK2,INA,CDC42,CDH10,LGI1,CHGB,RAB3C,NRXN3,CNR1,CNTN1,AKAP6,MYRIP,FAM171B,CRMP1,PLCXD3,NRSN1,RIMS2,ST18,KIF26A,DGKB,SCRN1,JAKMIP2,ZNF804A,CEP170,TMEM130,SNAP91,GRIN3A,CALN1,EBF1,EDIL3,ST8SIA3,EDNRB,ELAVL2,ELAVL3,ELAVL4,FABP7,TUBB3,ATP8A1,FGF13,NSG2,GABRA1,GABRB3,GAP43,SYT17,DNER,GFRA2,GPR22,RAPGEF4,STMN2,GRIA1,GRM7,FAM19A2,NEGR1,MSL1,DISP2,INSM1,KCND2,KCNQ2,KIF5A,KIF5C,SYTL4,MAOB,MAP2,MAP4,MAPT,MSI1,SCG3,RSPO2,NAP1L3,NCAM2,NDP,NEFM,NNAT,NOVA1,NRCAM,NTRK2,CLDN11,CNTN3,SLC10A4,GPR85,GNG2,DUSP26,SERPINI1,NALCN,PIK3R1,MAPK10,PRPH,EML5,PTPRO,RBBP6,SLC6A15,RGS4,RTN1,SCN3A,SCG5,ST8SIA1,CXXC4,SNAP25,SCN3B,KIF1B,NPAS3,C11orf87,SYT11,PRRC2C,SYT1,SYT4,CUX2,PCDHB7,TMEFF2,CADM1,CELF4,FSTL5,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.03E-46 5.27E-43 8.10E-45 7.38E-44 177 365 "CSMD2,RNF157,SNX30,ALCAM,SYT13,ANK2,ANK3,PPFIA2,APBB1,DGKD,VAT1L,APP,KIF1A,SEC11C,CDK5R1,GPC2,BAIAP3,CALB2,RUNX1T1,INA,SEPT7,LONRF2,CDC42,DCLK1,ADGRG1,CHGB,CLCN3,CLCN4,NRXN1,CNTN1,SLC4A8,PREPL,CRMP1,FEZ1,PLXNA4,KIAA0408,DNAJC6,MAGI2,TMEM130,SPOCK3,SV2A,NYAP1,DPYSL2,SEZ6L2,EEF1A2,EFNA3,KMT5B,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,ERBB4,NCALD,OLFM1,ACTL6B,HPCAL4,AGAP3,FAM49B,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB1,GABRB3,NCKAP1,GAP43,SRRM4,DNER,RAB30,MAP7D2,GNAO1,GNG3,GPM6A,PCLO,STMN2,GRIA2,PTPRT,KIF3A,LINGO1,CELF3,UBE2QL1,NEGR1,CELF5,KHK,KIF5C,KLC1,CAMK2N2,LSAMP,MAP6,CD200,GIT1,SCG3,SAMD14,MYO5A,BEX5,FXYD6,NCAM1,NELL2,NNAT,NRCAM,PAK3,PCDH9,GNG2,TMOD2,RETREG1,HMGCLL1,PPP2R2B,VSTM2L,PRKACB,PKIA,PRKCZ,PTPRN,MARCH1,RAB3A,RAB5B,RALGDS,REV3L,RGS4,RTN1,CSRNP3,SCN2A,SCN3A,LRRTM4,SMPD3,MRAS,SCG5,WDR47,NAPB,ZNF667,SMARCA4,RIMS1,SNAP25,SNCA,SCN3B,MYT1L,KIF21B,NMNAT2,ERC1,PEG10,BEX1,NPAS3,SRPK2,SEPT8,SEPT3,STXBP1,SYN2,SYP,SYT1,SYT4,TCEA1,TRIM2,PCDHA7,ATP13A2,RBFOX2,RUSC1,SSBP2,TUBB2A,UCHL1,DNAJC12,VGF,MEAF6,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,STMN4,TUBA1A,SCG2,MPPE1,RTN4,CERS6,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.37E-46 1.21E-42 1.83E-44 1.67E-43 178 370 "SLC12A5,ALCAM,GOLGA7B,SYT13,ANK2,ANK3,C6orf89,PPFIA2,VAT1L,APP,CADM3,KIF1A,ADAM23,SEC11C,CDK5R1,SGCE,BAIAP3,VSTM2A,MAP7,RUNX1T1,INA,SEPT7,LONRF2,CDC42,DCLK1,CCPG1,CHGA,CHGB,NRXN1,CNTN1,PREPL,CRMP1,SEC24C,PHF14,PNPLA8,CTNND2,KIAA0408,DNAJC6,ELMO1,TMEM130,SV2A,NYAP1,TRAPPC9,CPEB2,SEZ6L2,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,CLVS1,OLFM1,FGF12,HPCAL4,AGAP3,NPTN,NSG2,NSG1,PNMA2,SARAF,TVP23A,OGA,DKK3,GABRA1,GABRB3,GABRG2,GAP43,SRRM4,DNER,GNAO1,GNG3,GPM6A,PCLO,STMN2,TPPP,GRIA2,GRIA4,NR3C1,BTN2A1,KIF3A,CELF3,NEGR1,CELF5,KCNC2,KCNH2,KIF5C,KLC1,LSAMP,MAP6,MARK1,CD200,GIT1,SCG3,BEX5,HNRNPM,NCAM1,NELL2,NNAT,NRCAM,KSR2,PAK3,PCDH9,PCMT1,PCSK1,GNG2,TMOD2,SNX10,MINDY2,PPP2R2B,VSTM2L,PRKACB,PKIA,DEF8,PTPRN,RALGDS,RAP1GAP,REV3L,TTLL7,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,CPEB3,ST8SIA1,WDR47,CCDC88A,NAPB,SNAP25,SNCA,FAIM2,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,IQSEC2,CLASP2,POGZ,NACAD,SEPT3,STXBP1,SYP,SYT1,SYT4,DDHD2,CAMSAP2,FBXW11,PCDHA7,SIK3,ATP13A2,ASXL3,R3HDM1,RBFOX2,TUBB2A,FAM155A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,LRP8,STMN4,TUBA1A,SCG2,C12orf4,MRPL47,RTN4,CERS6,FAM219B,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.02E-46 3.58E-42 5.34E-44 4.87E-43 170 346 "ASIC1,KIAA1211,KIDINS220,BIN1,ANK2,ANK3,APLP1,CADPS,ASCL1,TTC9B,CDK5R1,SCAPER,GPC2,THSD7A,RUNX1T1,INA,SEPT7,CDH2,DCLK1,ADGRG1,NDST3,CNGA3,ZNF521,CRMP1,CSNK1E,NCAN,ST18,KIAA0408,KIF26A,BRINP1,DCC,JAKMIP2,ELMO1,CEP170,GSDME,DPYSL2,EBF1,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,EPB41,NRN1,TUBB3,MEX3B,NSG2,NSG1,PHYHIPL,GABRB3,GABRG2,GAD1,NKX6-2,GAP43,SRRM4,KIAA1841,DNER,C1QL1,PCDH11X,GNAS,GNG3,GPM6A,STMN2,GRIA2,C1QL4,GRIK2,FAM19A2,GUCY1A2,CELF3,UBE2QL1,ZHX1,NEGR1,HSF2,ATCAY,INSM1,TUBB2B,KIF5C,KLC1,STMN1,MAP6,SRSF12,CD200,SAMD5,MSI1,PTOV1,SCG3,TAGLN3,HS6ST3,MYO5A,NAP1L3,NCAM1,NEFM,NELL2,NEUROD1,NHLH1,NNAT,NOVA1,PAK3,PBX1,PCDH9,PCSK1,GNG2,GDAP1L1,PKM,SLC25A23,SCHIP1,POU3F2,PPP3CB,PRKACB,PKIA,MAPK8,NDUFS7,PSMA6,PLPPR1,PTPRN2,PTPRO,RALGDS,ARID4A,REV3L,PRRT2,ZFHX4,ROBO2,RPS6KA2,RTN1,AMER2,CSRNP3,SCN3A,SMPD3,SCG5,SYBU,WDR47,NAPB,CXXC4,SMARCE1,MYT1L,KIF21B,SOX11,CLASP2,SEPT3,GSE1,SYT1,SYT4,SYT5,CNTN2,KIAA1107,CLASP1,RBFOX2,SEZ6L,DOK6,RGMB,FNDC5,RUSC1,HSPBP1,TUBB2A,FAM155A,UCHL1,FMN2,NDRG4,CELF4,ZNF195,SHD,SLC38A1,STMN4,TUBA1A,TMEM178A,PCBP4,SLC17A6,PAK5,CBLN2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.96E-45 1.00E-41 1.45E-43 1.32E-42 119 194 "RNF157,CEP126,SYT13,ANK2,ANK3,APBB1,VAT1L,SHTN1,ATP1A3,MTMR9,KIF1A,CDK5R1,CAMK2B,RUNX1T1,CBLN1,INA,LONRF2,CDC42,NRXN1,TMEM59L,CNTN1,PREPL,CRMP1,CTNND2,KIAA0408,BRINP1,CEP170,FAM57B,EBF1,EDIL3,SEZ6L2,OPTN,EFNB3,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,RCAN2,EPHA5,NCALD,OLFM1,NSG2,NSG1,PNMA2,DKK3,GAP43,SRRM4,DNER,GNAL,GNAO1,GPM6A,STMN2,PTPRT,LINGO1,CELF3,ACOT7,SHISAL1,KCNMA1,KLC1,LSAMP,MAP6,CD200,GIT1,SCG3,HS6ST3,MYO5A,BEX5,NAP1L3,NCAM1,PAK3,PBX1,GNG2,TMOD2,GDAP1L1,VSTM2L,PRKACB,PKIA,PTPRN,MARCH1,RAB3A,BSDC1,ZFHX4,PNMA8A,ROBO2,HSD11B1L,RTN1,SCN2A,SCN3A,KIF21A,SHC4,NAPB,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,SPTAN1,CLASP2,SEPT3,STXBP1,SYT1,SYT4,KIAA0930,ATP13A2,SEZ6L,TUBB2A,UCHL1,VGF,CELF4,CADM2,SLC38A1,STMN4,SCG2,NAV3,SLC17A6,NETO1,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE76381_iPSMoleculeCountsPMLog2 1.96E-45 1.00E-41 1.45E-43 1.32E-42 119 194 "RNF157,CEP126,SYT13,ANK2,ANK3,APBB1,VAT1L,SHTN1,ATP1A3,MTMR9,KIF1A,CDK5R1,CAMK2B,RUNX1T1,CBLN1,INA,LONRF2,CDC42,NRXN1,TMEM59L,CNTN1,PREPL,CRMP1,CTNND2,KIAA0408,BRINP1,CEP170,FAM57B,EBF1,EDIL3,SEZ6L2,OPTN,EFNB3,TENM1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,RCAN2,EPHA5,NCALD,OLFM1,NSG2,NSG1,PNMA2,DKK3,GAP43,SRRM4,DNER,GNAL,GNAO1,GPM6A,STMN2,PTPRT,LINGO1,CELF3,ACOT7,SHISAL1,KCNMA1,KLC1,LSAMP,MAP6,CD200,GIT1,SCG3,HS6ST3,MYO5A,BEX5,NAP1L3,NCAM1,PAK3,PBX1,GNG2,TMOD2,GDAP1L1,VSTM2L,PRKACB,PKIA,PTPRN,MARCH1,RAB3A,BSDC1,ZFHX4,PNMA8A,ROBO2,HSD11B1L,RTN1,SCN2A,SCN3A,KIF21A,SHC4,NAPB,SNAP25,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,SPTAN1,CLASP2,SEPT3,STXBP1,SYT1,SYT4,KIAA0930,ATP13A2,SEZ6L,TUBB2A,UCHL1,VGF,CELF4,CADM2,SLC38A1,STMN4,SCG2,NAV3,SLC17A6,NETO1,CBLN2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000_K2 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 2.82E-45 1.44E-41 2.06E-43 1.87E-42 148 279 "ABR,PLEKHH1,KIAA1211,PTCHD1,PCDH19,LTBP4,GPRASP2,EPB41L5,SHTN1,ASCL1,NCOA1,ASTN1,KIF1A,BCL7A,PROM1,BMPR1B,HAP1,VSTM2A,LONRF2,CDH2,CDH8,ADGRG1,SRSF11,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN1,IGDCC3,CREB5,FEZ1,CTNND2,RIMS2,ST18,TOX,SCRN1,BRINP1,JAKMIP2,RUSC2,DMD,SHANK1,DTNA,MAMLD1,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EMX2,OLIG2,EPB41,EPHA5,APC2,ADGRV1,TUBB3,CHST15,MED12L,FOXG1,DPYSL4,FUT9,NRG3,PHYHIPL,ILDR2,GAD1,SRRM4,KIAA1841,PPARGC1A,RUNDC3A,MAP7D2,GNG3,GPM6A,GPM6B,PCLO,STMN2,GRIK2,RNF165,MFSD2A,SOX21,FAM222A,CELF3,TOX2,FRMD5,IGFBPL1,NEGR1,HES5,BRINP3,INSM1,KIF5C,MAP2,MBP,SHC3,MEIS2,SCG3,TAGLN3,NEXMIF,MYT1,NCAM2,NELL2,PAK3,PAX6,PCDH9,GDAP1L1,SEMA5B,TMEM38A,SLC25A23,PLXNB1,POU6F1,MAPK10,GDPD1,SLC22A23,APTX,MDGA2,ELOVL2,EML5,FEZF2,RTN1,STX1B,ATXN1,LRRTM4,LINC00461,HSPA4L,SCG5,KIF21A,NLGN1,MAST1,SNAP25,SOX2,SP4,NPAS3,CLSTN2,GSE1,FGD4,SYNE2,RHBDL3,SYP,SEMA4A,MCF2L,CUX2,PSD3,CCDC173,NR2E1,TRO,UCHL1,FMN2,DPYSL5,LRP8,STMN4,FZD3,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 4.79E-45 2.44E-41 3.44E-43 3.13E-42 212 494 "TTYH1,ABCF1,KLHL32,SLITRK1,ERMN,PCDH19,EPB41L5,SHTN1,ASCL1,ASTN1,ATP1A3,ATP2B2,KIF1A,CARMIL3,PROM1,BMPR1B,CACNA2D1,DIRAS1,HAP1,PTBP2,MAP7,INA,CDK11B,CDH2,KCNAB3,CDH8,MAGI1,ADGRG1,SRSF11,JAM2,LHX2,NRXN3,KIAA1549L,NRXN2,CNTFR,IQCK,IGDCC3,SLC35F1,FAM171B,CREB5,NCAN,CNTNAP2,FAM169A,ERC2,CTNND2,RIMS2,ST18,KATNAL2,TOX,SCRN1,JAKMIP2,DDX46,DLX1,RAB39B,DMD,CASP8AP2,DTNA,MAMLD1,EDNRB,PLXNC1,ELAVL2,ELAVL3,ELAVL4,RGS17,EMX2,OLIG2,SEZ6,RRAGB,ADGRV1,FABP7,ACSL4,TUBB3,TUBB4A,FGF12,FGFR3,FOXG1,KHDRBS3,DLL3,FUT9,B3GAT1,ADGRA1,TPPP3,ABLIM2,PHYHIPL,GABRB3,ILDR2,GAD1,GAD2,ARPP21,SALL3,SRRM4,ACSS1,KIAA1841,PPARGC1A,GLDC,DBF4,GLRB,TOX3,MAP7D2,GNAO1,GNG3,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,CIT,RNF165,MFSD2A,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,USP51,ATCAY,IGSF1,HES5,INSM1,TUBB2B,KIF5C,KTN1,MAP2,MBP,TM6SF1,SHC3,MEIS2,SCG3,MYT1,NASP,NEFM,NELL2,NOVA1,CLEC9A,NRCAM,NTRK2,IGSF11,ODF2,GPR137C,PAK3,PAX6,PCDH9,PRTG,SEMA5B,SLC25A23,FAT3,POU3F4,MAPK10,DIRAS2,GDPD1,MDGA2,ELOVL2,EML5,PTPRZ1,STRC,ENOX1,FEZF2,RFX4,FBXW7,RTN1,SALL1,ATXN1,LINC00461,SOX6,HSPA4L,SCG5,ZFP30,KIF21A,PPM1E,ARX,FHOD3,NLGN1,GKAP1,MAST1,SNAP25,SOX2,BDP1,LHFPL4,NPAS3,LMO3,C11orf87,LARP4,AJAP1,ACSBG1,SYT11,FGD4,SYNE2,SYN1,SYP,WWC1,CCDC173,NR2E1,SLAIN1,FAM181B,USP1,MGAT5B,WNT7A,ZIC1,ZIC2,ZIC3,ZNF23,FMN2,CELF4,ZBTB16,REEP1,DPYSL5,STMN4,DNAH10,FZD3,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.03E-44 5.23E-41 7.26E-43 6.62E-42 172 358 "TMEM132B,TMCC3,KIDINS220,TBC1D14,ALCAM,PCDH10,SYT13,ANK2,ANK3,APBB1,APP,CADPS,PCDHGB4,KIF1A,SEC11C,BMP7,CALB1,CAST,RUNX1T1,INA,SEPT7,LONRF2,CDC42,CHGB,SOCS6,NRXN1,TMEM59L,CNTN1,ZFP28,CRMP1,SLC32A1,CNTNAP2,PLXNA4,SDC3,CALY,KIAA0408,DNAJC6,TMEM130,RHOBTB1,PLPPR4,SNAP91,SV2A,SEZ6L2,EFNB3,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,DMTN,EPHA5,SPEG,MRPL37,FGF13,HPCAL4,POMT1,NSG2,NSG1,PNMA2,FUT9,DKK3,GABRB3,GAP43,DNER,GFRA1,PCDH17,C1QL1,GLRB,TOX3,STARD3,GNAL,GNAO1,GNG3,GPM6A,GPM6B,PCLO,STMN2,GRIA2,KIF3A,CELF3,ACOT7,NEGR1,CELF5,HTR2A,ATCAY,IDH3A,KIF5C,KLC1,MSANTD3-TMEFF1,LSAMP,MARK1,KCTD6,CD200,SCG3,MYO5A,BEX5,FXYD6,NCAM1,PAK3,PBX1,PCSK1,GNG2,TMOD2,LRP12,SEPT4,SLC36A4,PPP2R2B,PKIA,NDUFS7,APTX,PTPRN,PLEKHB2,RET,REV3L,ROBO1,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,SLC1A2,WDR47,NAPB,CPEB4,OGDHL,SNAP25,SNCA,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SRPK2,CLASP2,SSTR2,SEPT3,STXBP1,VPS13A,SYP,SYT1,SYT4,KIAA0930,PCDHA7,ATP13A2,RBFOX2,LRRC24,TUB,TUBB2A,CADM1,UCHL1,DNAJC12,VGF,NPDC1,ZNF708,ATP6V0E2,NDRG4,CELF4,REEP1,FSTL5,PLPPR5,UPF3A,STMN4,SCG2,RTN4,NETO2,AP3B2,ST8SIA2,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.18E-44 6.04E-41 8.27E-43 7.54E-42 171 355 "ACTN1,GPRIN1,SORCS1,KIDINS220,SEMA6A,SYT13,ANK2,ANK3,APBB1,VAT1L,APP,PLA2G4C,ZSCAN18,KIF1A,ADGRB2,SEC11C,BCL2L2,CDK5R1,RUNX1T1,CBLN1,INA,SYNGR3,SEPT7,LONRF2,CDC42,DCLK1,CDH18,CHGA,CHGB,NRXN1,CLU,TMEM59L,CNTN1,PREPL,CRMP1,SOCS5,CTNND2,KIAA0408,DOCK4,RIMS3,BRINP1,DNAJC6,FBXL5,COPS7A,LYPD1,SNAP91,SV2A,CD99L2,CPEB2,EBF1,SEZ6L2,OPTN,TENM1,ELAVL2,PLEKHA1,ELAVL3,BSCL2,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,OLFM1,HPCAL4,ATP2C1,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRG2,GAP43,DNER,GNAO1,GNG4,GPM6A,CCDC184,EML4,PCLO,STMN2,GRIA2,PTPRT,KIF3A,CELF3,IGSF21,CELF5,ATCAY,KCNB1,KIF5C,MSANTD3-TMEFF1,LSAMP,MARK1,SCG3,HS6ST3,MYO5A,MYO9A,BEX5,FXYD6,NCAM1,NEFM,SMIM11A,NTRK2,OPCML,PAK3,PCSK1,PCSK2,GNG2,TMOD2,EPN1,PPM1B,PPP2R2B,VSTM2L,PRKACB,PKIA,PROX1,PTPRE,PTPRN,PTPRN2,PTPRO,RAB3A,RIT2,PNMA8A,RTN1,CSRNP3,ATXN1,SCN2A,SCN3A,ELMOD1,ASRGL1,SCG5,NLGN1,WDR47,NAPB,SNAP25,SNCA,SCN3B,FAM219A,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,IQSEC2,EPB41L3,SEPT3,STXBP1,SYP,SYT1,SYT4,PCDHA7,ATP13A2,FBXL16,RBFOX2,TUBB2A,UCHL1,DNAJC12,PLPPR2,VGF,ZNF540,NDRG4,TCEAL7,CELF4,REEP1,DPYSL5,CADM2,RGMA,STMN4,SCG2,RTN4,CERS6,ST8SIA2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.89E-44 9.66E-41 1.31E-42 1.19E-41 124 211 "CSMD3,ADCYAP1R1,ADD2,PNMA8B,PCDH10,UNC79,APBA2,APBB1,VAT1L,LGR5,SLC7A14,ASTN1,CADM3,KIF1A,TTC9B,NRP2,HAP1,INA,LONRF2,DCLK1,CHGB,RAB33A,SULT4A1,PICK1,AKAP12,CRMP1,FEZ1,PLXNA4,NRSN1,SCRN1,DNAJC6,SV2A,SRGAP3,SEZ6L2,FRY,CELSR3,KCNMB2,NCALD,RRAGB,CEND1,CACNG3,TUBB3,FDFT1,OLFM1,FGF13,ACTL6B,AFF2,NSG2,NSG1,TPPP3,MTHFD2,SYT17,SRRM4,CPLX1,IGSF5,GFRA1,C1QL1,RUNDC3A,STMN2,ARHGAP36,HLF,DISP2,LIX1,TUBB2B,KCNA4,KIF5A,L1CAM,SYTL4,MAOB,MAP6,MAPT,MARK1,DDX25,MYT1,NCAM1,NEFH,NELL2,NNAT,NTRK3,KSR2,PCDH9,SLC10A4,PFKP,GDAP1L1,SERPINE2,PLP1,PMP22,PRKCB,MAPK10,PROX1,PTPRN,RALGDS,ZMAT4,RET,RGS4,RTN1,SATB1,SCN2A,SCG5,CCDC92,CXXC4,MAST1,SNRPN,UNC80,NFASC,NACAD,SEPT3,STXBP1,SYT11,SYN2,SYP,ASTN2,CUX2,FBXL16,RUNDC3B,TUBB2A,UCHL1,SLAIN1,ATP6V0E2,DPYSL5,PARP6,STMN4,TUBA1A,AP3B2" Coexpression Atlas PCBC_ratio_ECTO_vs_DE_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.47E-44 1.26E-40 1.68E-42 1.53E-41 364 1100 "TTYH1,ABR,ABHD6,GALNT16,ADCY6,TXNDC16,PLA2G6,ALCAM,SRPX,MRTFA,AMPD2,BIN1,SEMA7A,LCORL,APBA2,APBB1,EPB41L5,APLP1,DGKD,FAM131A,VAT1L,CDK10,IGDCC4,ZSCAN18,ASTN1,ATP1A2,STX16,CADM3,ATP6V1G2,ATP6V0A1,DOCK11,ADAM23,ADAM15,LINC00847,BBS2,MPDZ,BCL7A,BMP7,MTMR3,AP1M1,SGCE,CAST,HIP1R,CDH8,LGI1,CDO1,UBE2L6,CIART,ADGRG1,RCBTB2,CBARP,RAB28,CLU,TMEM184B,HOMER3,CNTFR,COL4A5,SLC25A27,COL9A1,ZNF521,IGDCC3,ZNF385A,CPS1,FAM171B,SEC31B,PREPL,ENTPD4,SH2B1,HAPLN1,CRY2,CLIP3,CST3,PNPLA8,GREB1,ARHGEF4,CTNND2,GPSM1,FAM131B,BOC,HDAC9,TCAF1,ZFYVE16,ZEB2,HEPH,RUSC2,TMEM130,LYPD1,RHOBTB1,SV2A,SGSM2,ARNT2,DLG4,DMD,DNM1,DMPK,CD99L2,CDON,ARRDC4,DTNB,AASDH,TSPAN5,EDN1,KLHL5,EFNB3,MBNL2,RASA4,PLEKHA1,ING4,EML1,EMX2,HSD17B14,MTSS1L,NCALD,EFS,TMEM74,EZH1,REEP2,FABP7,ACSL4,EFEMP1,TESK2,SLC9B2,SPSB4,FGFR3,BAIAP2,TMEM164,PRKAG2,FHL1,SUCO,SCARA3,MEX3B,TMEM175,TACC2,USP21,TRIM16,GPR153,TPPP3,DOT1L,BRSK1,ZNF512,GAA,ILDR2,FAM184B,DENND2A,FAM120B,GAP43,TMEM8B,WASF3,GDF1,GPR162,SESN1,AHDC1,GGT7,MALT1,RND1,GLDC,TOX3,KIAA1958,LOXL3,GPR19,STON1,LPAR4,CROCCP2,CACFD1,LINC01089,PTPN5,COQ10A,SOX21,GUCY1B1,IGSF21,CPT1C,HSD17B1,ATCAY,MSL1,C5orf24,HES5,LIX1,IL6ST,TMEM240,IL11RA,ZNF385B,ITGA7,ITPKB,OLFM3,GATD1,LRRC4B,LSAMP,CLEC18A,MAN2A2,MAP2,MATN2,ADAM11,MEIS2,MEST,KCTD6,MID1,MOV10,SESN3,CCDC80,MSI1,BCO1,NRBP2,SAMD14,TCEAL5,FXYD6,NELL2,NUCB2,NUMA1,OCRL,KCNK10,PAX6,PCDHGC3,PRTG,ENPP2,GPR173,GNG2,CDK14,PGAM2,NLGN3,PCDH18,PLXNB1,LRP12,SCHIP1,SDK2,POU3F2,NKAIN4,VSTM2L,CNNM2,LRRC49,LAMA1,PTN,PTPN13,PTPRD,RIPOR1,TMEM231,OXR1,FEZF2,PRRT2,FIGN,RIC8B,ZFHX4,PNMA8A,KIRREL1,BAALC,KIAA0895L,EMID1,CNTNAP3,LGR4,MELTF-AS1,PAQR6,HSD11B1L,ATAT1,WLS,YJEFN3,MAPK12,MIR124-2HG,SBF1,SEC14L1,ASRGL1,SCG5,ARX,FNDC3A,FHOD3,NLGN1,ST3GAL3,NBPF1,PKNOX2,SLC6A8,CDK5RAP3,SCMH1,MTERF2,EFHD1,GKAP1,SMARCC2,TTC17,ANKRD36,SNCA,PALLD,WDTC1,SOX1,SOX2,SPATA7,SOX11,TSPYL2,COLGALT2,STOX1,SMOC1,LRRC4,MAPK8IP3,ELOVL4,SEPT8,RGL1,PHLDB1,SYT11,VAMP1,ARHGEF9,SYT1,C12orf76,DDHD2,MCF2L,UNC5D,ADGRL3,WSCD1,DMXL2,ZFP90,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA3,PCDHB15,PCDHB10,PCDHB9,PCDHB4,CRTC1,AHCYL2,FAM200B,DICER1-AS1,ZMAT3,TGFBR3,THBS4,TIAM1,TRH,LRRC24,FNDC5,CA14,SSBP2,TUB,EIF4ENIF1,CCDC136,MICAL1,TSPAN11,NPDC1,ELFN1,ATP6V0E2,EMX2OS,CRB2,TCEAL7,ZBTB16,AMZ1,DPYSL5,MAP3K12,EMSY,DNALI1,RGMA,GDPD5,ADAMTS9,TMEM178A,SEMA3B,GAL3ST3,PPP1R3F,CAB39L,TRIM16L,MVB12B,FZD3,DOCK8,KAT6A,FAM219B,TTC7A,PIANP,FRMD6,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 7.17E-44 3.65E-40 4.81E-42 4.38E-41 136 248 "SLITRK1,RNF157,PTCHD1,LTBP4,GPRASP2,PPFIA2,EPB41L5,PHYHD1,SHTN1,ASTN1,KIF1A,PROM1,HAP1,VSTM2A,LONRF2,CDH2,CDH8,LHX2,NRXN3,KIAA1549L,NRXN1,NRXN2,CREB5,CRMP1,AATK,FEZ1,NCAN,CNTNAP2,SLITRK5,RIMS2,TOX,SCRN1,JAKMIP2,RUSC2,DMD,SHANK1,DTNA,MAMLD1,ELAVL2,TMEM35A,EMX2,EPHA5,EPHB1,APC2,ADGRV1,TUBB3,CHST15,FHL1,FOXG1,DPYSL4,FUT9,NRG3,PHYHIPL,GABRB3,ILDR2,SRRM4,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,TDRKH,STMN2,GRIK2,RNF165,MFSD2A,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,USP51,NEGR1,ATCAY,ZIC5,HES5,BRINP3,KTN1,MEIS2,TAGLN3,NEXMIF,NASP,NCAM2,NELL2,NOVA1,NRCAM,PAK3,PAX6,PCDH9,SEMA5B,TMEM38A,POU6F1,MAPK10,MDGA2,ELOVL2,EML5,PTPRZ1,ENOX1,FEZF2,RTN1,STX1B,ATXN1,LRRTM4,HSPA4L,SCG5,KIF21A,ARX,NLGN1,SMARCD3,SOX2,NPAS3,LMO3,CLSTN2,SYT11,FGD4,RHBDL3,ASTN2,SEMA4A,TMEM178B,ACSL6,CUX2,TCF7L2,PSD3,NR2E1,PRMT8,SLAIN1,RBFOX3,ZIC3,FMN2,LYPD6,DPYSL5,LRP8,FZD3,KLHDC1,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.84E-43 1.45E-39 1.88E-41 1.71E-40 113 184 "ASIC1,KIAA1211,KIDINS220,ANK2,ANK3,APLP1,CADPS,ASCL1,CDK5R1,GPC2,THSD7A,RUNX1T1,INA,SEPT7,DCLK1,ADGRG1,CRMP1,CSNK1E,NCAN,ST18,KIAA0408,DCC,JAKMIP2,CEP170,DPYSL2,EBF1,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,EPB41,NRN1,TUBB3,MEX3B,NSG2,NSG1,PHYHIPL,GAD1,GAP43,SRRM4,DNER,GNG3,GPM6A,STMN2,GRIA2,GRIK2,CELF3,UBE2QL1,ZHX1,ATCAY,INSM1,TUBB2B,KIF5C,KLC1,STMN1,MAP6,CD200,SCG3,TAGLN3,NCAM1,NEFM,NEUROD1,NHLH1,NNAT,NOVA1,PAK3,PBX1,PCDH9,GNG2,SLC25A23,SCHIP1,POU3F2,PRKACB,PKIA,MAPK8,PLPPR1,PTPRN2,PTPRO,RALGDS,ARID4A,ZFHX4,RTN1,AMER2,CSRNP3,SCN3A,SMPD3,SCG5,WDR47,MYT1L,KIF21B,SOX11,CLASP2,SEPT3,GSE1,SYT1,CNTN2,KIAA1107,RBFOX2,RGMB,FNDC5,TUBB2A,UCHL1,FMN2,NDRG4,CELF4,ZNF195,SLC38A1,STMN4,TUBA1A,PCBP4,PAK5,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.87E-43 1.46E-39 1.88E-41 1.71E-40 158 319 "DPF1,ASIC1,CSMD2,SLITRK1,SLC12A5,GPR158,SMIM17,PCDH10,ANK3,PI16,PPFIA2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,SYNPR,KIAA1549L,NRXN1,NRXN2,NIPBL,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,CTNND2,ST18,CCDC144A,BRINP1,ZNF804A,TMEM130,SPOCK3,OLIG1,DPP6,ATN1,FAM135B,RASA4,ELAVL3,ELAVL4,RGS17,EN2,OLIG2,DMTN,FABP7,TAOK3,FGF12,C1orf61,SGIP1,NSG2,NSG1,ABLIM2,FYN,ZMAT1,GABRA1,GABRG1,GABRG2,JPH4,GAP43,DNER,MAP7D2,GNG3,GPD1,GPM6A,GRK4,STMN2,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,TOX2,PACSIN2,NEGR1,SHISA6,HSP90AA1,HES5,BRINP3,KCNC2,KCND2,STMN1,PIK3AP1,SCG3,NEXMIF,NCAM1,NELL1,NELL2,NFIX,NNAT,NOVA1,KSR2,OPCML,PDGFRA,SERPINI1,SLC25A23,NXPH1,POU6F1,LRRN3,PLPPR1,CCDC40,RIT2,RORB,SYNDIG1,RTN1,SCN2A,SCN2B,SCN3A,ASIC4,TRIM46,HSPA4L,SYBU,TRIM67,LIMCH1,SNAP25,MYT1L,SST,GSE1,SYT1,SYT5,TAL1,KIAA1107,SIN3B,RALYL,ZFPM2,CDH22,CSMD1,TNS1,TP53BP1,RUNDC3B,RFTN2,TMEFF2,UBTF,VSNL1,CELF4,REEP1,FSTL5,ZNF184,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.62E-43 2.36E-39 2.98E-41 2.72E-40 121 207 "SLITRK1,SORCS1,C1QTNF4,DPP10,ANK2,SLC7A14,ASCL1,ASPH,ASTN1,ADAM23,TTC9B,ADGRB3,CDK5R1,ARHGEF7,CACNA1B,KALRN,INA,CDH10,LGI1,CHGB,RAB33A,NRXN3,NRXN2,CNR1,CNTN1,COL9A1,COL9A3,MYRIP,FAM171B,CRHBP,CRMP1,PLCXD3,NRSN1,KIF26A,SCRN1,BRINP1,JAKMIP2,ZNF804A,TMEM130,GRIN3A,HS3ST4,CALN1,SEZ6L2,CELSR3,ELAVL2,ELAVL3,ELAVL4,TUBB3,CORO2B,ATP8A1,OLFM1,DPYSL4,PNMA2,GAP43,SYT17,DNER,GFRA1,GFRA2,PCDH17,PCDH11X,PCSK1N,B4GALNT4,GPR22,STMN2,GRIA1,GRM7,NEGR1,DISP2,INSM1,TUBB2B,KCNK2,KCNQ2,KIF5A,KIF5C,MAP4,MAP6,MAPT,MMP16,MSI1,RSPO2,NCAM2,NDP,NEFM,NNAT,NRCAM,NTRK2,OPRL1,CLDN11,PIRT,SLC10A4,GPR85,DUSP26,NALCN,PRKAR1B,MAPK10,PRPH,SNRK,PTPRG,PTPRO,RET,RGS4,ARMH4,RIMKLA,RTN1,SCN3A,ST8SIA1,SLC8A3,LGI3,SNAP25,SCN3B,ZNF423,NPAS3,C11orf87,SYT11,TMEM178B,CUX2,PCDHB7,TMEFF2,CELF4,FSTL5,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.37E-43 2.74E-39 3.42E-41 3.12E-40 157 317 "ASIC1,DSCAML1,KIAA1211,KIDINS220,ANK2,ANK3,APLP1,CADPS,ASCL1,CDK5R1,GPC2,CACNA2D1,CALB2,THSD7A,SPAG9,RUNX1T1,CCNH,INA,CBFA2T2,SEPT7,DCLK1,ADGRG1,CRMP1,CSNK1E,NCAN,NRSN1,ST18,KIAA0408,DCC,JAKMIP2,ZEB2,CEP170,GRIN3A,DPYSL2,EBF1,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,EPB41,SEZ6,EFS,NRN1,CLVS1,TUBB3,MEX3B,NSG2,DACH2,NSG1,DLL3,B3GAT1,PHYHIPL,GAD1,GAP43,SRRM4,DNER,MMADHC,GFRA1,SPIN1,MSL3,GLUL,GNG3,GPM6A,STMN2,GRIA2,GRIK2,TMEM25,CELF3,UBE2QL1,ZHX1,IGFBPL1,HSP90AA1,ATCAY,SCRT2,INSM1,TUBB2B,KIF5C,KLC1,STMN1,MAP6,CD200,SCG3,TAGLN3,NCAM1,NEFM,NEUROD1,NEUROD2,NFIX,NHLH1,NNAT,NOVA1,PAK3,PBX1,PCDH9,GNG2,SLC25A23,SCHIP1,POU3F2,POU6F1,PRKACB,PKIA,MAPK8,PLPPR1,PTPRN2,PTPRO,PID1,RALGDS,ARID4A,RGS4,ZFHX4,KLHDC8A,RPS20,RTN1,AMER2,CSRNP3,SCN3A,HES6,SMPD3,SOX6,MRAS,SCG5,WDR47,EPC1,MYT1L,KIF21B,SOX11,CLASP2,SEPT3,GSE1,SYT1,ROBO3,CNTN2,KIAA1107,ZEB1,TCF12,PSD3,CRB1,RBFOX2,RGMB,FNDC5,TUBB2A,UCHL1,TSPAN11,FMN2,NDRG4,CELF4,ZNF195,SLC38A1,STMN4,PRDM8,TUBA1A,SCG2,TMEM163,PCBP4,PAK5,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 9.73E-43 4.96E-39 6.12E-41 5.58E-40 287 796 "TTYH1,ABAT,CSMD2,NDRG2,ADCY2,ADCYAP1R1,SORCS1,ERMN,OSBPL6,SPARCL1,SEMA6A,ALCAM,CEP126,PCDH10,CCDC146,LRRC4C,IGDCC4,ARHGAP5,ASCL1,PDE8B,PCDHGB4,CCDC181,ATP1A2,RNF182,CADM3,KIF1A,ADGRB1,BARD1,MPDZ,SEC11C,BCHE,PROM1,BMP7,DST,CA12,CACNB2,THSD7A,VXN,HIP1R,SPAG9,MAP7,PRC1,CD81,SEPT7,CDC25B,KCNAB3,LGI1,CDO1,CDR1,ADGRG1,FOXN3,CHN2,JAM2,KIAA1549L,NRXN1,CLU,TPP1,TMEM59L,TJP2,QKI,CNGA3,ARHGEF6,AKAP7,COL9A1,IGDCC3,NECTIN3,CREB5,NCOR2,SNCAIP,TENM4,LRIG1,FEZ1,NCAN,CST3,SDC3,CTNND2,ARHGAP32,TOX,RASSF2,DBI,FBXL5,LYPD1,SV2A,NTM,KBTBD11,OLIG1,CASP8AP2,DPP6,RCAN1,DTNA,EDNRB,FSD1L,EFNB3,SUGP2,EGFR,TNK2,OLIG2,LRRC17,EPHB1,EPS8,ERBB4,ETV1,ADGRV1,F5,NSRP1,FAM198B,FABP7,EFEMP1,ZMYND10,FGFR3,C1orf61,IQCG,FLNC,NBEA,PDLIM5,CSPG5,FUT9,TPPP3,PHYHIPL,DKK3,MEGF10,GABRG1,ILDR2,SEPT9,DNER,GATM,GFAP,PCDH17,HEPN1,LUZP2,DCLK2,PSRC1,GPM6A,GPM6B,STON1,GRIK2,GRM3,GRM5,FAM107A,ADAMTS6,HAS2,FRMD3,SCRG1,CFAP126,C2orf72,IGSF1,HES5,LIX1,IL6ST,LRRTM3,ITGAV,KCND2,KCNN3,LIFR,FGFBP3,C2orf80,PACRG,MAN2A2,MAP6,LDLRAD3,MSI1,NRBP2,MT3,SCG3,MTTP,RSPO2,MXI1,FXYD6,NCAM1,NELL1,NELL2,NFIA,NFIX,NPTX2,NTRK2,OMG,OPCML,OPHN1,PRTG,PDGFRA,ENPP2,CDK14,SERPINE2,SEMA5B,PLP1,PLTP,PLXNB1,PMP2,RC3H2,PSAT1,SCHIP1,FAT3,NXPH1,IRX1,LRRN3,NKAIN4,GRAMD1C,HYDIN,MASP1,GDPD2,PTCH1,PLPPR1,ELOVL2,SPDL1,PTN,PTPRO,PTPRZ1,PEX2,TMEM231,ZCWPW1,ARID4A,VEPH1,RDX,RFX4,RIT2,ZFHX4,KLHDC8A,NEK11,WLS,CLIP1,RYR3,S100B,SALL1,SARS,ATXN1,SCN3A,ASRGL1,PUF60,BCAN,CLSTN1,SLC1A2,SLC1A3,EPN2,WDR47,SIRT2,SLC15A2,ZFP1,LIMCH1,SOX2,TNIK,SOX5,FNBP1,ENKUR,NPAS3,ATP10B,ITPRID2,SMOC1,INKA2,KANK1,SULF2,SEPT3,MLC1,TACR1,WWC1,VWA3A,WSCD1,TCF4,ZEB1,TCF12,PSD3,OBSL1,CCDC173,ENHO,HEY1,TMPO,CSMD1,CABIN1,SEZ6L,PPIL6,RFTN2,CADM1,FLRT2,FAM181B,USP1,TSPAN11,CFAP52,TRIM9,TFIP11,PRDM2,LRP8,RGMA,STMN4,PCDH15,FZD3,MARCH8,RTN4,DPF3" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500 facebase_RNAseq_e10.5_NeuroEpith_central_2500 Gudmap RNAseq 1.03E-42 5.24E-39 6.39E-41 5.83E-40 478 1622 "DPF1,CPNE2,TTYH1,ABCF1,ARID1A,FMNL2,CCDC85A,ADD2,SORCS1,PLEKHH1,UNC5A,KIAA1211,KLHL13,WDR35,CEP126,AMPH,CDC42BPA,ANK2,FGD2,C6orf89,USP28,PHF12,PPFIA2,APC,EPB41L5,APLP1,PHYHD1,VAT1L,USP37,SHTN1,SHROOM2,SEMA4G,TMEFF1,CADPS,CAPRIN2,PTCH2,ZBTB10,ASTN1,ATM,ZNF583,CADM3,NOL4,ATP6V1G2,KIF1A,BCHE,BCL7A,NRP2,ZNF599,PROM1,SYNJ1,ST3GAL5,ARHGEF7,FUBP1,PRMT9,SGCE,MYRF,CFAP410,CACNA1A,CACNB2,HAP1,PTBP2,CAMK2A,BRSK2,SPAG9,PRC1,SHISA7,USP2,MTMR7,C1orf52,CDK11B,CDC25B,CDH2,DCLK1,ARHGAP33,MAGI1,NUMBL,CACNA2D2,ADGRG1,CBARP,CHGB,CHM,JAM2,ARHGAP22,SLIT2,NRXN3,KIAA1549L,NRXN1,DNAJB5,C4orf33,QKI,NIPBL,IGLON5,CNR1,IQCK,WHRN,COL4A5,SLC25A27,SLC4A8,MYRIP,ZNF521,IGDCC3,NECTIN3,SLC35F1,FAM171B,CRMP1,CRY2,CLIP3,ABCG1,AATK,FEZ1,CNTNAP2,FAM169A,UBXN2A,PHF14,PLCXD3,CTNND2,PYGO1,KATNAL2,KIF26A,RASSF2,LIN54,KIAA0586,CTIF,DNAL1,ARMCX4,MYEF2,SNAP91,SRGAP3,ARNT2,DMD,USP3,SLC29A4,SHANK1,CASP8AP2,DTNA,DUSP9,MAMLD1,AASDH,SEZ6L2,PHC2,TMTC1,FSD1L,RBM12,EIF4G2,ELAVL2,ELAVL4,EML1,C8orf37,EMX2,HSD17B14,PLEKHO1,ENO2,EPB41,EPHB1,ANKRD13B,SLC43A2,SRRM1,ERBB4,ETV1,RTN3,CEND1,ADGRV1,REEP2,WAC,FABP7,TBC1D16,TUBB4A,CEP78,FKTN,OLFM1,SPSB4,FGFR3,MAD2L2,AMOTL2,CAMSAP1,FHL1,FOXM1,AFF2,COQ5,DPYSL4,CINP,SMC2,ZNF605,KHDRBS3,FUT9,NRG3,PHYHIPL,MEGF11,GABRA3,DENND2A,BRPF3,ATP8A2,ACSS1,KIAA1841,GFRA2,CSDC2,GGT7,PPARGC1A,RUNDC3A,NTNG2,GLDC,TOX3,CBX1,KIAA1958,KDM2B,DCLK2,GNAO1,GNG3,PSRC1,GPD2,GPM6A,GPM6B,CCDC184,GPR19,CECR2,CNTRL,STMN2,GRIK2,RNF165,MFSD2A,PSIP1,GUCY1A2,RNFT2,CELF3,TOX2,FRMD5,DDX19B,KLF12,BACH2,HSF2,HSP90AA1,SHISAL1,DOCK7,LRRCC1,BRINP3,TUBB2B,KCNH2,KCNJ16,KIF2A,KIF5C,KTN1,L1CAM,LRRC4B,LMO1,ARHGAP12,LSAMP,ZFYVE27,MAP2,MAP6,MAPT,MBP,SYT9,TM6SF1,SHC3,MEST,KITLG,PPM1L,MSI1,TAGLN3,MDGA1,MYCN,LINC00672,MYO5A,NASP,ZC3H12B,RCOR2,NEFM,NNAT,NOVA2,SLC11A2,NRCAM,NTRK2,KSR2,ODF2,PAK3,PDE1C,PDE4A,GPR173,TMOD2,FAM98B,PFKFB4,PGAM2,NLGN3,SERPINI1,SEMA5B,SNX10,GPSM2,SLC25A23,PLXNB1,MAPKAP1,RC3H2,PSAT1,SPATA6,FAT3,NKAIN4,RASGEF1B,PKIA,PRKCB,MAPK4,EPDR1,PROX1,GDPD1,RELN,SIDT1,PTCH1,ELOVL2,SPDL1,PTN,ZIK1,PTPN13,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,RAD51D,FAM184A,ARID4A,RADX,REV3L,ERI2,RFX2,RFX3,RFX5,RNASEL,SETD5,MYH14,GSTCD,ROM1,TMEM206,RPE,SGSM1,ADAL,RIMKLA,MEG3,RTKN,CLIP1,RTN1,CCDC112,RMI1,SALL1,SATB1,LRRTM4,FAM19A1,SCN8A,ZFP2,SOX6,ASRGL1,HSPA4L,SCG5,SH3BGR,KIF21A,PPM1E,FERMT1,CHD9,FBXO11,FHOD3,CCDC92,ST3GAL3,ST8SIA1,WDR37,ZNF365,SLC1A3,DHX30,LIMS2,RUFY2,FAM214B,PKNOX2,YPEL4,CCDC88A,KBTBD4,SLIT1,CXXC4,GKAP1,SMARCD3,INAVA,RIMS1,SNAP25,ANKFN1,KDM4B,SCN3B,SOX2,SOX5,KIF21B,SOX11,SOX15,SP2,SP4,ZC3H13,SPTAN1,KIF1B,RBM26,ATP10B,CLSTN2,POGZ,SAMSN1,NKAIN2,INKA2,ZSCAN29,SULF2,SEPT3,ACSBG1,SYT11,FGD4,SYNE2,VPS13A,SYP,SYT5,MMS19,TACC1,SEMA4A,CAMTA1,WWC1,WSCD1,CUX2,TCF7L2,ZEB1,TRIM2,TCF12,CLASP1,AZIN2,PSD3,NSD1,FRYL,AHCYL2,SIK3,SIRT1,AKTIP,HEY1,PIK3R5,TP53BP1,C9orf85,PRMT8,STXBP4,TRPC1,CA14,TSC1,TTC3,TMEFF2,CADM1,SLAIN1,NSD2,WNT7A,KLC2,NPDC1,ZFP37,ZNF711,ZNF23,ZNF24,KCNT2,ZFP41,ATP6V0E2,LYPD6,ZBTB16,REEP1,ZNF184,DPYSL5,SMARCAD1,EMSY,LRP8,SHD,SLC38A1,STOX2,LMAN2L,TUBA1A,GAL3ST3,FIP1L1,PCBP4,WNK3,WNK2,FZD3,PHTF2,VANGL2,TTC7A,AP3B2,ST8SIA2,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.09E-42 5.54E-39 6.60E-41 6.01E-40 112 183 "ACLY,ADCY2,SLITRK1,KIDINS220,ALCAM,ANK2,ANK3,APLP1,ATP2B1,CADM3,CDK5R1,GPC2,INA,SEPT7,NRXN2,CRMP1,RIMS2,ST18,DOCK4,DNAJC6,JAKMIP2,CEP170,NYAP1,EBF1,EDIL3,SEZ6L2,EEF1A2,ELAVL2,ELAVL3,ELAVL4,BSCL2,EN2,ENO2,EYA1,ACSL4,TUBB3,OLFM1,NSG2,NSG1,GABRG2,GAP43,SRRM4,DNER,GNAO1,GNG3,GPM6A,CCDC184,STMN2,GRIA4,GRIK1,KIF3A,CELF3,ACOT7,NEGR1,ATCAY,TUBB2B,KIF5C,KLC1,L1CAM,MSANTD3-TMEFF1,MAP4,MAP6,CD200,TAGLN3,BEX5,NCAM1,NEFM,NELL2,PCDH9,GNG2,TMOD2,GDAP1L1,SLC25A23,PPP2R2B,LRRN3,PRKACB,ARID4A,RTN1,RXRG,SEMA6D,CSRNP3,SCN2A,SCN3A,SCG5,KIF21A,RUFY2,NAPB,SNAP25,SCN3B,MYT1L,BEX1,LMO3,CLASP2,SEPT3,SYT1,SYT4,CAMSAP2,CNTN2,KIAA1107,RBFOX2,FNDC5,TUBB2A,TMEFF2,FAM155A,UCHL1,TCEAL7,CELF4,REEP1,FSTL5,STMN4,TUBA1A,PCBP4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 1.09E-42 5.54E-39 6.60E-41 6.01E-40 112 183 "ACLY,ADCY2,SLITRK1,KIDINS220,ALCAM,ANK2,ANK3,APLP1,ATP2B1,CADM3,CDK5R1,GPC2,INA,SEPT7,NRXN2,CRMP1,RIMS2,ST18,DOCK4,DNAJC6,JAKMIP2,CEP170,NYAP1,EBF1,EDIL3,SEZ6L2,EEF1A2,ELAVL2,ELAVL3,ELAVL4,BSCL2,EN2,ENO2,EYA1,ACSL4,TUBB3,OLFM1,NSG2,NSG1,GABRG2,GAP43,SRRM4,DNER,GNAO1,GNG3,GPM6A,CCDC184,STMN2,GRIA4,GRIK1,KIF3A,CELF3,ACOT7,NEGR1,ATCAY,TUBB2B,KIF5C,KLC1,L1CAM,MSANTD3-TMEFF1,MAP4,MAP6,CD200,TAGLN3,BEX5,NCAM1,NEFM,NELL2,PCDH9,GNG2,TMOD2,GDAP1L1,SLC25A23,PPP2R2B,LRRN3,PRKACB,ARID4A,RTN1,RXRG,SEMA6D,CSRNP3,SCN2A,SCN3A,SCG5,KIF21A,RUFY2,NAPB,SNAP25,SCN3B,MYT1L,BEX1,LMO3,CLASP2,SEPT3,SYT1,SYT4,CAMSAP2,CNTN2,KIAA1107,RBFOX2,FNDC5,TUBB2A,TMEFF2,FAM155A,UCHL1,TCEAL7,CELF4,REEP1,FSTL5,STMN4,TUBA1A,PCBP4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.69E-42 8.63E-39 1.02E-40 9.26E-40 107 170 "CSMD3,ADCYAP1R1,NME5,PCDH10,ANK2,VAT1L,SLC7A14,CADPS,KIF1A,TTC9B,INA,DCLK1,CHGB,RAB3C,NRXN1,CNTFR,FAM171B,CRMP1,CLIP3,FEZ1,PLXNA4,NRSN1,RIMS2,SCRN1,JAKMIP2,ZNF804A,SPOCK3,DLG2,EDNRB,ATL1,ELAVL2,ELAVL4,DENND4A,EYA1,FABP7,CACNG3,TUBB3,TUBB4A,FDFT1,FGF13,SGIP1,NSG2,NSG1,TPPP3,GABRB3,GAP43,SYT17,SRRM4,IGSF5,GFRA2,PCSK1N,GNAO1,GNG3,STMN2,GRIA2,GRIA4,CELF3,ARHGAP36,DISP2,LIX1,KIF5C,L1CAM,SYTL4,MAP6,SCG3,TAGLN3,MYT1,NCAM1,NCAM2,NEFM,NELL2,NNAT,NOVA1,PCBP3,PCDH9,SLC10A4,PENK,GDAP1L1,PMP22,MAPK10,PROX1,PRPH,STK32A,EML5,PTPRZ1,RET,RGS4,RTN1,SCN2A,FAM19A1,SCG5,SNAP25,SNRPN,SCN3B,SST,EPB41L3,SYT11,SYP,SYT1,CUX2,RUNDC3B,TMEFF2,CADM1,UCHL1,FSTL5,DPYSL5,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.48E-42 1.27E-38 1.47E-40 1.34E-39 164 343 "SNX30,ALCAM,SYT13,ANK2,ANK3,C6orf89,PPFIA2,VAT1L,APP,MTMR9,KIF1A,SEC11C,CDK5R1,BAIAP3,CACNA1A,CAMK2B,VSTM2A,RUNX1T1,INA,SEPT7,CDC25B,LONRF2,CDC42,DCLK1,CHGA,CHGB,NRXN1,CNTN1,ABI3BP,PREPL,CRMP1,SLC45A1,CTNND2,KIAA0408,DNAJC6,TMEM130,SV2A,RABGAP1L,KBTBD11,NYAP1,DPYSL2,RCAN1,EDIL3,SEZ6L2,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,SLC43A2,NCALD,TUBB4A,PRMT5,OLFM1,HPCAL4,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRB3,GABRG2,GAP43,SRRM4,DNER,GNAO1,GNG3,GPM6A,PCLO,STMN2,TPPP,GRIA2,PTPRT,KIF3A,RNF165,LINGO1,CELF3,UBE2QL1,NEGR1,CELF5,C2CD4C,GPR62,KHK,KIF5C,KLC1,CAMK2N2,LSAMP,MAP4,MAP6,MARK1,CD200,GIT1,SCG3,MYO5A,BEX5,FXYD6,NCAM1,NNAT,NRCAM,PAK3,PCDH9,GNG2,TMOD2,PPP2R2B,VSTM2L,PRKACB,PKIA,PSD,PTPRN,RAB3A,RALGDS,RAP1GAP,ARID4A,REV3L,RTN1,CSRNP3,SCN2A,SCN3A,MRAS,SCG5,WDR47,NAPB,RIMS1,SNAP25,MAPKBP1,SNCA,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,KIF1B,SS18,SEPT8,SEPT3,STXBP1,SYP,SYT1,SYT4,PCDHA7,ATP13A2,MTMR14,RBFOX2,NTSR2,TTC3,TUBB2A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,DPYSL5,STMN4,TUBA1A,SCG2,RTN4,CERS6,NETO1,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 6.86E-42 3.50E-38 4.02E-40 3.67E-39 114 191 "ALCAM,SYT13,ANK2,ANK3,PPFIA2,VAT1L,APP,KIF1A,SEC11C,CDK5R1,BAIAP3,RUNX1T1,INA,SEPT7,LONRF2,CDC42,DCLK1,CHGB,NRXN1,CNTN1,PREPL,CRMP1,KIAA0408,DNAJC6,TMEM130,SV2A,NYAP1,SEZ6L2,TENM1,ELAVL2,ELAVL3,TMEM35A,EPB41L1,RCAN2,EPHA5,NCALD,OLFM1,HPCAL4,NSG2,NSG1,PNMA2,SARAF,DKK3,GAP43,SRRM4,DNER,GNAO1,GNG3,GPM6A,PCLO,STMN2,GRIA2,KIF3A,CELF3,NEGR1,CELF5,KIF5C,KLC1,LSAMP,CD200,GIT1,SCG3,BEX5,NCAM1,NNAT,NRCAM,PAK3,PCDH9,GNG2,TMOD2,PPP2R2B,VSTM2L,PRKACB,PKIA,PTPRN,RALGDS,REV3L,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,WDR47,NAPB,SNAP25,SNCA,SCN3B,KIF21B,NMNAT2,PEG10,BEX1,SEPT3,STXBP1,SYP,SYT1,SYT4,PCDHA7,ATP13A2,RBFOX2,TUBB2A,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,STMN4,TUBA1A,SCG2,RTN4,CERS6,CBLN2" Coexpression Atlas BM Top 100 - frontal lobe BM Top 100 - frontal lobe Body Map 1.17E-41 5.95E-38 6.76E-40 6.16E-39 64 72 "SLC12A5,UNC5A,SYT13,CDK5R1,KALRN,VXN,VSTM2A,CCK,SYNGR3,DLGAP1,CHN1,SYNPR,LHX2,KIAA1549L,NGEF,CABP1,GDA,RIMS3,SV2B,DNM1,ELAVL2,ELAVL4,OLFM1,FOXG1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG2,GAD1,ARPP21,GAP43,GPM6A,RAPGEF4,STMN2,GRIA2,WIF1,CELF5,KCNJ4,KCNQ2,CREG2,C2orf80,MAP4,NELL2,NPTX1,NRGN,OPCML,PCDH8,SERPINI1,PRKCB,DIRAS2,RGS4,SCN2A,SLC1A2,SLC8A1,SNAP25,SCN3B,C11orf87,SST,SYN2,SYT1,FBXL16,VSNL1,SLC17A7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.19E-41 6.07E-38 6.82E-40 6.22E-39 166 353 "XKR4,TMEM132B,SLITRK1,ADCY6,TMCC3,KIDINS220,INTS2,ALCAM,ALK,SYT13,ANK2,ANK3,APBB1,APP,SLC7A14,CADPS,ASTN1,RNF182,KIF1A,SEC11C,CALB1,RUNX1T1,INA,SEPT7,LONRF2,CDC42,CHGA,CHGB,NRXN1,TMEM59L,CNTN1,CRMP1,TENM4,PLXNA4,PITPNM3,SDC3,CALY,KIAA0408,DCAF8,DNAJC6,TMEM130,SNAP91,SV2A,SEZ6L2,TSPAN5,EFNB3,CELSR3,PLXNC1,TENM1,ELAVL2,ELAVL3,TMEM35A,PLEKHO1,EPB41L1,RCAN2,DMTN,EPHA5,FDFT1,FGF13,ACTL6B,HPCAL4,NSG2,DACH2,NSG1,PNMA2,B3GAT1,DKK3,GABRB3,GAP43,DNER,PCDH17,GNAL,GNAO1,GNG3,GNG4,GPM6A,PCLO,STMN2,GRIA2,KIF3A,CELF3,ACOT7,NEGR1,CELF5,ATCAY,JAK2,KCNC2,KIF5C,KLC1,MSANTD3-TMEFF1,LSAMP,MARK1,SCG3,HS6ST3,MYO5A,BEX5,FXYD6,NCAM1,NELL2,NTRK3,KCNK10,PAK3,PBX1,PCSK1,GNG2,TMOD2,PPP2R2B,PKIA,PXK,PTPRN,ZNF793,ATG16L1,BSDC1,REV3L,RTN1,CSRNP3,SCN2A,SCN3A,SCG5,SLC1A2,URGCP,EPN2,WDR47,SLC8A1,NAPB,CPEB4,SNAP25,SNCA,SCN3B,KIF21B,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SRPK2,CLASP2,CAMTA2,SEPT3,STXBP1,SYP,SYT1,SYT4,KIAA0930,ARHGEF12,PCDHA7,ATP13A2,RBFOX2,NEIL2,TUBB2A,CADM1,UCHL1,DNAJC12,VGF,NPDC1,ATP6V0E2,NDRG4,CELF4,REEP1,CADM2,STMN4,SCG2,SLC17A6,RTN4,NETO2,ST8SIA2" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500 facebase_RNAseq_e10.5_Emin_MedNas_2500 Gudmap RNAseq 1.73E-41 8.82E-38 9.80E-40 8.93E-39 429 1415 "DPF1,CPNE2,TTYH1,ABCF1,ACHE,NCKAP5,ARID1A,DSCAML1,CCDC85A,ADD2,SORCS1,ADORA1,UNC5A,KIAA1211,ADRB2,KLHL13,OSBPL1A,KIAA1324,CEP126,DOC2A,LRCH2,ANK2,USP28,APC,EPB41L5,MAGEE2,VAT1L,BCAS1,LGR5,MADD,ARHGAP5,ARRB2,CADPS,CAPRIN2,PTCH2,ASTN1,ATM,CADM3,NOL4,ATP6V1G2,KIF1A,ADGRB2,BLM,ZNF599,PROM1,ST3GAL5,ARHGEF7,FUBP1,WASF1,CFAP410,CA4,CA12,CACNA1A,CALB1,THSD7A,PTBP2,CAMK2A,CH25H,BRSK2,PRC1,SHISA7,USP2,CBFA2T2,ENTPD2,CDK11B,CDH2,KCNAB3,CACNA2D2,ADGRG1,FOXN3,CHGB,CHN1,JAM2,ARHGAP22,SLIT2,NRXN3,KIAA1549L,NRXN1,C4orf33,QKI,NIPBL,IGLON5,CNR1,CNTFR,IQCK,SLC4A7,SLC4A8,MYRIP,IGDCC3,CP,NECTIN3,SLC35F1,FAM171B,CRMP1,CRY2,CLIP3,CRYM,CSF3R,FEZ1,IPCEF1,PLCH2,CNTNAP2,FAM169A,PPP1R16B,PHF14,PLCXD3,GREB1,CFAP61,CTNND2,FGFR1OP2,KATNAL2,RIPOR2,TOX,RASSF2,LIN54,KIAA0586,CTIF,DNAJC6,ZNF804A,DDX46,SNAP91,SRGAP3,ARNT2,DLG4,DMD,USP3,CASP8AP2,DPP6,DTNA,FAM78B,MAMLD1,WDPCP,EDNRB,FSD1L,EIF4G2,ELAVL2,ELAVL4,C8orf37,EMX2,EPB41,ERBB4,CDKL3,EXTL1,CEND1,EXTL2,KATNAL1,ADGRV1,MRVI1,NRN1,REEP2,WAC,FABP7,TUBB4A,CORO2B,SPSB4,FGFR3,CAMSAP1,FHL1,AFF2,DPYSL4,SMC2,ZNF605,PRELID3A,DACH2,CSPG5,FUT9,NRG3,PHYHIPL,GABRA1,GABRA3,IP6K3,IQGAP2,HIGD1B,TMEM8B,MTHFD2,SYT17,C15orf41,ATP8A2,WASF3,KIAA1841,TUBGCP4,TUBA8,ADAM28,GFRA2,GGT7,PPARGC1A,RUNDC3A,NTNG2,GK,GLDC,DBF4,GLRB,TOX3,CBX1,KIAA1958,GNAO1,GNG3,GPM6A,GPM6B,GPR12,GPR19,CECR2,GRK4,CNTRL,STMN2,GRIK2,CIT,RNF165,MFSD2A,PSIP1,GUCY1A2,FAM107A,RNFT2,GUCY1B1,CELF3,TOX2,FRMD5,INSYN1,HMGCR,HPCA,HSF2,HSP90AA1,SMAP1,SHISAL1,DOCK7,LRRCC1,LIX1,TUBB2B,LRRTM3,KCNC1,KCNH2,KCNJ5,KCNJ16,KIF2A,KIF5C,KIT,L1CAM,LRRC4B,SFXN5,LMO1,HECTD2,LSAMP,LSS,MAP2,MAP6,MAPT,MARK1,SYT9,SHC3,MID1,PPM1L,MSI1,NRBP2,TAGLN3,MDGA1,SAMD14,MYCN,LYRM9,LINC00672,MYO5A,NEXMIF,NASP,RCOR2,NEFM,NNAT,NOVA2,CLEC9A,NRCAM,NTRK2,KSR2,ODF2,PAK3,PDE3B,PDE1B,TMOD2,FAM98B,ABCB1,SERPINI1,SEMA5B,PIK3CD,SNX10,GPSM2,PLCB2,SLC25A23,ZNF426,SPATA6,FA2H,FAT3,PKIA,PRKAR1B,MAPK4,MAPK8,PROX1,GDPD1,MASP1,RELN,SLC22A23,LAMA1,SIDT1,GDPD2,MDGA2,CNTLN,PTCH1,ELOVL2,SPDL1,ZIK1,EML5,PTPRO,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,VEPH1,ERI2,RFX3,RNASEL,SETD5,MYH14,CCDC25,RIMKLA,SOX8,KCNIP3,CLIP1,RTN1,STX1B,SALL1,LRRTM4,SCN8A,ELMOD1,ZFP2,SOX6,SELL,SFPQ,HSPA4L,SCG5,KIF21A,SH3GL2,PPM1E,FERMT1,CHD9,FHOD3,CCDC92,NLGN1,ST8SIA1,ANKRD6,SLC1A3,DHX30,WDR47,PKNOX2,CCDC88A,ZNF334,SLIT1,CXXC4,SMARCE1,SNAP25,CABCOCO1,ANKFN1,SCN3B,SOX2,SOX5,SPATA7,SOX11,ERC1,ZNF423,ZC3H13,CLSTN2,NKAIN2,INKA2,ZSCAN29,NEK4,SEPT3,ACSBG1,SYT11,SYNE2,VPS13A,C3orf70,SYT5,CAMTA1,WSCD1,CUX2,ZEB1,TCF12,CLASP1,SIRT1,AKTIP,GALNT17,NACC2,TNFRSF1B,R3HDM1,PIK3R5,TP53BP1,PRMT8,STXBP4,TRPC1,TRPS1,CA14,SLAIN1,FAM181B,USP1,NSD2,WNT7A,KLC2,ZFP37,ZNF711,ZNF23,ZFP41,AGMO,ZBTB16,REEP1,ZNF184,EML6,DPYSL5,ANKS1B,SMARCAD1,EMSY,LRP8,STOX2,TUBA1A,TMEM178A,GAL3ST3,FIP1L1,WNK3,WNK2,FZD3,NETO2,AP3B2,ST8SIA2,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.92E-41 9.78E-38 1.07E-39 9.79E-39 163 344 "TMEM132B,TMCC3,KIDINS220,KLHL13,PCDH10,BEGAIN,ANK2,ANK3,PPFIA2,APLP1,AMER3,APP,CADPS,MARK4,CDK5R1,GPC2,LDLRAD4,CACNA1E,CARS,RUNX1T1,INA,SEPT7,DCLK1,CHGB,NRXN1,NRXN2,CNTN1,BTF3L4,IFFO1,CRMP1,RGS6,IPCEF1,NCAN,PLXNA4,SLITRK5,ERC2,RIMS2,RUBCN,KIAA0408,DCC,CEP170,SNAP91,SV2B,NTM,DPP6,FAM135B,ELAVL2,ELAVL3,ELAVL4,TMEM35A,EN2,RCAN2,EPHA5,ERBB4,FABP7,TUBB3,FGF13,NPTN,NSG2,NSG1,FUT9,BRSK1,PHYHIPL,DKK3,GABRB3,GAP43,SRRM4,DNER,GFRA1,COPS8,GNAO1,GNG3,GPM6A,GPR22,STMN2,GRIA2,GRM5,CELF3,TOX2,NEGR1,SHISAL1,INSM1,KIF5C,KLC1,L1CAM,LSAMP,CD200,PTOV1,TCEAL5,BEX5,NAP1L3,NCAM1,NNAT,PBX1,PCSK2,SLC10A4,GNG2,TMOD2,OLA1,CDK14,PDZRN4,FAT3,POU3F2,POU6F1,PRKACB,PKIA,PTPRO,PTPRZ1,RALGDS,REV3L,ROBO1,ROBO2,RTN1,AMER2,SEMA6D,CSRNP3,SCN2A,SCN3A,SMPD3,SOX6,SCG5,SH3GL3,CLSTN1,WDR47,CPEB4,SNCA,SCN3B,MYT1L,KIF21B,SOX11,ZHX3,NMNAT2,MYCBP2,PEG10,BEX1,LMO3,SRPK2,SEPT3,SYT1,SYT4,TAC1,TMEM178B,KIAA1107,EHBP1,ENHO,RBFOX2,SEZ6L,DOK6,TUB,TUBB2A,TMEFF2,UCHL1,ZNF17,CELF4,REEP1,DPYSL5,STMN4,TUBA1A,PAK5,RNF170,PIANP,NETO2,ST8SIA2" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4 facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4 Gudmap RNAseq 4.82E-41 2.46E-37 2.67E-39 2.44E-38 418 1371 "DPF1,TTYH1,ABCF1,ARID1A,FMNL2,CCDC85A,SORCS1,KIAA1211,KLHL13,WDR35,CEP126,AMPH,CDC42BPA,ANK2,FGD2,C6orf89,USP28,PHF12,PPFIA2,APC,EPB41L5,APLP1,PHYHD1,VAT1L,USP37,SHROOM2,TMEFF1,CADPS,CAPRIN2,PTCH2,ZBTB10,ASTN1,ATM,ZNF583,CADM3,NOL4,ATP6V1G2,KIF1A,BCHE,BCL7A,ZNF599,PROM1,SYNJ1,ST3GAL5,ARHGEF7,FUBP1,PRMT9,SGCE,MYRF,CFAP410,CACNA1A,CACNB2,HAP1,PTBP2,CAMK2A,BRSK2,SPAG9,PRC1,SHISA7,USP2,MTMR7,C1orf52,CDK11B,CDC25B,CDH2,DCLK1,ARHGAP33,MAGI1,NUMBL,CACNA2D2,ADGRG1,CBARP,CHGB,CHM,JAM2,SLIT2,KIAA1549L,NRXN1,DNAJB5,C4orf33,QKI,NIPBL,IGLON5,CNR1,IQCK,WHRN,SLC25A27,SLC4A8,MYRIP,ZNF521,IGDCC3,NECTIN3,SLC35F1,FAM171B,CRMP1,CRY2,CLIP3,FEZ1,CNTNAP2,FAM169A,UBXN2A,PHF14,PLCXD3,PYGO1,KATNAL2,RASSF2,LIN54,KIAA0586,CTIF,DNAL1,ARMCX4,MYEF2,SNAP91,SRGAP3,ARNT2,DMD,USP3,SLC29A4,SHANK1,CASP8AP2,DTNA,DUSP9,MAMLD1,AASDH,PHC2,TMTC1,FSD1L,RBM12,EIF4G2,ELAVL2,ELAVL4,EML1,C8orf37,PLEKHO1,ENO2,EPB41,ANKRD13B,SLC43A2,SRRM1,ERBB4,ETV1,RTN3,CEND1,ADGRV1,REEP2,WAC,FABP7,TBC1D16,TUBB4A,CEP78,FKTN,OLFM1,SPSB4,MAD2L2,AMOTL2,CAMSAP1,FHL1,FOXM1,AFF2,COQ5,DPYSL4,CINP,SMC2,ZNF605,KHDRBS3,FUT9,NRG3,PHYHIPL,MEGF11,GABRA3,DENND2A,BRPF3,ATP8A2,ACSS1,KIAA1841,GFRA2,CSDC2,GGT7,PPARGC1A,RUNDC3A,NTNG2,TOX3,CBX1,KIAA1958,KDM2B,DCLK2,GNAO1,GNG3,PSRC1,GPD2,GPM6A,GPM6B,GPR19,CNTRL,STMN2,GRIK2,RNF165,MFSD2A,PSIP1,RNFT2,CELF3,TOX2,FRMD5,DDX19B,KLF12,BACH2,HSF2,HSP90AA1,SHISAL1,DOCK7,LRRCC1,TUBB2B,KCNH2,KCNJ16,KIF2A,KIF5C,KTN1,L1CAM,LRRC4B,ARHGAP12,LSAMP,ZFYVE27,MAP2,MAP6,SYT9,TM6SF1,MEST,PPM1L,TAGLN3,MDGA1,MYCN,LINC00672,MYO5A,NASP,ZC3H12B,RCOR2,NEFM,NOVA2,SLC11A2,ODF2,PAK3,PDE1C,PDE4A,GPR173,TMOD2,FAM98B,PFKFB4,PGAM2,NLGN3,SEMA5B,SNX10,GPSM2,SLC25A23,MAPKAP1,RC3H2,PSAT1,SPATA6,FAT3,NKAIN4,RASGEF1B,PKIA,PRKCB,MAPK4,EPDR1,PROX1,GDPD1,RELN,PTCH1,ELOVL2,SPDL1,PTN,ZIK1,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,RAD51D,FAM184A,ARID4A,REV3L,ERI2,RFX2,RFX3,RFX5,RNASEL,SETD5,MYH14,GSTCD,ROM1,TMEM206,RPE,SGSM1,ADAL,RIMKLA,MEG3,RTKN,CLIP1,RTN1,CCDC112,RMI1,SALL1,SATB1,FAM19A1,SCN8A,ZFP2,SOX6,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,CHD9,FBXO11,FHOD3,CCDC92,ST3GAL3,ST8SIA1,WDR37,ZNF365,DHX30,RUFY2,FAM214B,PKNOX2,YPEL4,CCDC88A,KBTBD4,SLIT1,CXXC4,GKAP1,SMARCD3,RIMS1,SNAP25,ANKFN1,KDM4B,SCN3B,SOX5,KIF21B,SOX11,SP2,SP4,ZC3H13,SPTAN1,KIF1B,RBM26,CLSTN2,POGZ,SAMSN1,INKA2,ZSCAN29,SULF2,SEPT3,SYT11,FGD4,SYNE2,VPS13A,SYP,SYT5,MMS19,CAMTA1,WSCD1,CUX2,TCF7L2,ZEB1,TRIM2,TCF12,CLASP1,AZIN2,PSD3,NSD1,FRYL,SIK3,SIRT1,AKTIP,HEY1,PIK3R5,TP53BP1,C9orf85,PRMT8,STXBP4,TSC1,TTC3,CADM1,SLAIN1,NSD2,WNT7A,KLC2,NPDC1,ZFP37,ZNF711,ZNF23,ZNF24,KCNT2,ZFP41,ATP6V0E2,LYPD6,REEP1,ZNF184,SMARCAD1,EMSY,LRP8,SHD,SLC38A1,STOX2,LMAN2L,TUBA1A,GAL3ST3,FIP1L1,WNK3,WNK2,FZD3,PHTF2,VANGL2,TTC7A,AP3B2,ST8SIA2,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 6.56E-41 3.34E-37 3.60E-39 3.28E-38 158 330 "AXIN2,KIDINS220,ZNF608,DISP3,ANK2,ANK3,APBA2,APLP1,DACT3,GPC2,WASF1,CACNA2D1,CALB1,THSD7A,KALRN,BRSK2,INA,ADGRG1,NDST3,LHX2,MAP4K4,AKAP6,MAGED1,HS3ST5,CRMP1,CLIP3,NCAN,CNTNAP2,CTNND2,ST18,TCAF1,RIMS3,SCRN1,DCC,DCTN1,HP1BP3,FAM57B,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,ENO2,EPB41,EPHA5,EPHB1,STX2,ERBB4,NCALD,EFS,NRN1,TUBB3,CORO2B,MEX3B,C1orf61,IP6K2,GPR153,NSG1,DLL3,B3GAT1,TPPP3,GAP43,C15orf41,SRRM4,DNER,GNG3,GNG4,GPM6B,TMEM121B,CECR2,STMN2,C1QL4,CELF3,UBE2QL1,IGFBPL1,ATCAY,INSM1,KIF5C,KLC1,L1CAM,LMO2,MAP4,MAP6,MEIS1,MEIS2,AFDN,CD200,SCG3,TAGLN3,MDGA1,MYBPC1,MYO6,NCAM1,RCOR2,NEFM,NELL1,NHLH1,NNAT,NUMA1,PAK3,PALM,PCMT1,PDPK1,GNG2,GDAP1L1,PKM,SLC25A23,NECAB2,POU3F2,NKAIN4,MAPK8,SLC22A23,PTPRG,NKAIN1,RALGDS,ZFHX4,ROBO1,ROBO2,HUNK,RTN1,SCN3A,HES6,SEC14L1,PDZRN3,KIF21B,SOX11,NMNAT2,BEX1,NFASC,CLASP2,SSTR2,EPB41L3,CEP68,GSE1,SYT1,SYT4,TAC1,FAM208A,CNTN2,KIAA0930,ZEB1,PUM2,FRYL,RBFOX2,FNDC5,UCHL1,VAV2,ZIC1,ZIC2,ZIC3,FMN2,NDRG4,TCEAL7,STMN4,SCG2,PCBP4,SLC17A6,CBLN2" Coexpression Atlas BM Top 100 - temporal lobe BM Top 100 - temporal lobe Body Map 9.24E-41 4.71E-37 5.01E-39 4.57E-38 65 75 "SLC12A5,ERMN,UNC5A,CDK5R1,KALRN,VXN,VSTM2A,CCK,DLGAP1,CHN1,SYNPR,LHX2,NGEF,CNR1,GDA,PLPPR4,SV2B,ELAVL4,OLFM1,HPCAL4,FOXG1,GABRA1,GABRA2,GABRA4,GABRA5,GABRB1,GABRG2,GAD1,ARPP21,GAP43,GPM6A,RAPGEF4,STMN2,GRIA2,WIF1,CELF5,KCNQ2,CREG2,C2orf80,MAP4,MOBP,NPTX1,NPTX2,NRGN,OPCML,PCDH8,PDE1A,SERPINI1,PRKCB,DIRAS2,RGS4,SCN2A,FAM19A1,SLC1A2,SNAP25,SCN3B,DDN,C11orf87,SST,SYN2,SYT1,TAC1,FBXL16,VSNL1,SLC17A7" Coexpression Atlas BM Top 100 - hippocampus BM Top 100 - hippocampus Body Map 1.06E-40 5.38E-37 5.67E-39 5.16E-38 67 79 "SLC12A5,ERMN,UNC5A,CDK5R1,CACNA1E,KALRN,CAMK2A,CAMK2B,VXN,CCK,DLGAP1,CHN1,SYNPR,LHX2,CNR1,GDA,PLPPR4,OLIG1,OLFM1,FOXG1,GABRA2,GABRA5,GABRB1,GABRG2,GAD1,CPLX2,GPM6A,RAPGEF4,STMN2,GRIA1,GRIA2,WIF1,HPCA,CELF5,KCNQ2,CREG2,C2orf80,MAP4,MOBP,MOG,NELL2,NPTX1,NPTX2,NRGN,OPCML,PCDH8,PDE1A,DIRAS2,SCN2A,FAM19A1,PPM1E,SLC1A2,SLC8A1,SPHKAP,SCN3B,DDN,C11orf87,SST,NCDN,SYN2,SYT1,TAC1,FBXL16,CELF4,SLC17A7,CPNE4,JPH3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.07E-40 5.45E-37 5.68E-39 5.17E-38 186 427 "CSMD3,SLITRK1,RNF157,SORCS1,USP31,TAOK1,PCDH10,FAM135A,DPP10,APAF1,APC,PHYHD1,VAT1L,SLC7A14,CADPS,ASCL1,ASTN1,RNF182,ADAM23,ADGRB3,BCHE,NRP2,LDLRAD4,CACNA1B,CACNA2D1,INA,CDH10,DCLK1,SRSF11,CHGB,RAB3C,CNR1,CNTN1,AKAP6,MYRIP,SLC35F1,FAM171B,VCAN,DZIP3,ERC2,PLCXD3,NRSN1,ST18,HDAC9,DGKB,SCRN1,DNAJC6,JAKMIP2,ZNF804A,MYEF2,MFAP3L,SNAP91,GRIN3A,CALN1,CPEB2,DYRK1A,EBF1,EDIL3,ST8SIA3,HIPK3,TENM1,ELAVL2,ELAVL4,CALCRL,EPHA5,ETV1,EYA1,FABP7,TMEM132C,TUBB3,DLC1,ATP8A1,KIAA1109,FGF13,FOXF2,SGIP1,PDLIM5,DACH2,CHL1,AHCYL1,IQGAP2,GAP43,SYT17,DNER,GFRA1,GFRA2,PCDH17,PCDH11X,GPR22,STMN2,GRIA1,GRIA2,GRM7,FAM19A2,WIF1,KLF12,IFI16,IL6ST,INSM1,KCNC2,KCNMA1,KCNQ2,KIF5C,SYTL4,HECTD2,MAP2,MAP4,MAPT,CHIC1,MKLN1,MMP16,RSPO2,MYH3,NAP1L2,NCAM2,NDP,NEFM,NFIA,NOVA1,NTRK2,CLDN11,CNTN3,SLC10A4,GPR85,TMOD2,DUSP26,SERPINI1,NALCN,HMGCLL1,PRRX1,FAT3,MAPK10,PRPH,EML5,PTPRO,FAT4,RBBP6,RET,RGS4,ZFHX4,SETD5,RTN1,CSRNP3,SCN3A,LRRTM4,FAM19A1,NTNG1,ST8SIA1,ANKRD6,NAPB,CXXC4,SNAP25,SCN3B,SOX2,SOX5,ZHX3,NPAS3,C11orf87,CLASP2,EPB41L3,ELOVL4,SYT11,SYN2,SYT4,ADGRL3,AGTPBP1,FBXW11,CUX2,CLASP1,PCDHB3,NSD1,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRPS1,CADM1,RPRM,WRN,FSTL5,STMN4,LMAN2L,FAM13C,MSRB3,SOCS4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.40E-40 2.24E-36 2.31E-38 2.11E-37 113 194 "ASPHD1,CSMD3,ADCYAP1R1,PCDH10,ANK2,VAT1L,SLC7A14,CADPS,ASCL1,KIF1A,ADAM23,CCK,INA,DCLK1,CHGA,CHGB,RAB3C,NRXN1,CNTFR,FAM171B,CRMP1,CLIP3,FEZ1,PLXNA4,ERC2,NRSN1,RIMS2,SCRN1,JAKMIP2,ZNF804A,SNAP91,SPOCK3,DLG2,RAB39B,EDNRB,ATL1,CACNG7,ELAVL2,ELAVL4,KCNMB2,EYA1,FABP7,TUBB3,TUBB4A,FGF13,SGIP1,NSG1,PHYHIPL,GABRB3,GAP43,SYT17,SRRM4,IGSF5,GFRA1,GFRA2,PCSK1N,GNAO1,GNG3,TDRKH,STMN2,GRIA2,CELF3,ACOT7,SCRG1,LIX1,KIF5C,L1CAM,LMO1,SYTL4,PACRG,MAP6,SCG3,TAGLN3,NAP1L2,NCAM2,NEFM,NELL2,NNAT,NOVA1,PCBP3,SLC10A4,GDAP1L1,SERPINE2,MAPK10,PRPH,ELOVL2,STK32A,EML5,PTPRZ1,RET,RGS4,RGS7,RTN1,FAM19A1,SCG5,KIF21A,SNAP25,SNRPN,SCN3B,SOX10,SST,SEPT3,SYT11,NUDT10,SYP,SYT1,CUX2,TMEFF2,CADM1,UCHL1,FSTL5,STMN4,SCG2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.67E-40 2.89E-36 2.95E-38 2.69E-37 116 203 "KCNH8,SYN3,SORCS1,DISP3,ANK2,PPFIA2,CADPS,ADAM23,ADGRB3,BCHE,CACNA2D1,MAP7,INA,CDH10,LGI1,CHN1,RAB3C,NRXN1,CNR1,CNTN1,PCYT1B,FAM171B,PHACTR3,ERC2,RIMS2,ST18,KIAA0408,HDAC9,DGKB,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SRGAP3,DLG2,RAB39B,CPEB2,FAM78B,EBF1,EDIL3,ST8SIA3,EDNRB,ELAVL2,ELAVL3,ELAVL4,RCAN2,EYA1,CLVS1,FABP7,SGIP1,PHYHIPL,GABRB3,GAP43,FAXC,MAP7D2,DCLK2,GNAO1,TDRKH,GPR22,PCLO,GRIA2,GRIA4,GRIK2,UBE2QL1,HSPA1L,KIF5C,MAP2,MMP16,ADAM22,SCG3,NAP1L2,NCAM2,NEFM,ALDH1L2,NOVA1,NRCAM,PCDH9,GNG2,TMOD2,NALCN,PPP2R2B,LRRN3,PKIA,STK32A,EML5,PTPRZ1,RADX,SLC6A15,RGS7,NUDT11,ARMH4,RYR3,CSRNP3,SCN3A,HSPA4L,KIF21A,SH3GL3,CNKSR2,SNAP25,SNCA,SCN3B,SOX2,TNIK,HECW1,EPB41L3,ELOVL4,NUDT10,SYT1,SYT4,CUX2,CADM1,RBFOX3,KCNT2,MKRN3,FSTL5,SCG2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.11E-39 5.65E-36 5.71E-38 5.20E-37 131 249 "TTYH1,SYN3,CCDC85A,RNF157,PCDH10,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,NCOA1,ASTN1,ADAM23,ADGRB3,JAZF1,CACNA1A,THSD7A,VSTM2A,LONRF2,CDH8,EVI5L,FOXN3,SLIT2,KIAA1549L,NRXN1,IGLON5,ARHGEF6,SLC4A8,SLC35F1,FAM171B,CREB5,AATK,CSF2RA,FEZ1,ERC2,CTNND2,PYGO1,TOX,SCRN1,DCC,RUSC2,NTM,KBTBD11,DMD,SHANK1,DTNA,MAMLD1,EDNRB,TMEM35A,EMX2,ENO2,EPHA5,APC2,ADGRV1,TUBB3,ATP8A1,CHST15,DPYSL4,NRG3,ACSS1,PPARGC1A,PCDH11X,MAP7D2,GPM6B,TDRKH,MFSD2A,TOX2,NEGR1,BRINP3,LRRC4B,MEIS2,ADAM22,NRBP2,TAGLN3,NCAM2,NEFM,NELL2,NFIA,NTRK2,PAX6,PCDH9,PGAM2,SEMA5B,TMEM38A,SLC25A23,FAT3,POU3F4,POU6F1,MAPK10,MDGA2,ENOX1,PRRT2,MEG3,RTN1,STX1B,CSRNP3,ATXN1,LRRTM4,NTNG1,NLGN1,SLC1A3,SMARCD3,SOX2,NPAS3,CLSTN2,MAPK8IP3,DIP2A,RHBDL3,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,CUX2,TMEM151B,PSD3,THRA,NR2E1,UCHL1,SLAIN1,PLPPR2,ZIC1,FMN2,LYPD6,DPYSL5,SHD,STMN4,WNK2,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.38E-39 7.03E-36 7.03E-38 6.40E-37 286 819 "RALGAPA1,EMILIN3,SLITRK1,SLC12A5,SORCS1,USP31,TAOK1,C1QTNF4,PCDH10,ALK,OGT,DPP10,ANK2,ANK3,APAF1,APC,DGKD,SHTN1,SLC7A14,SEMA4G,ASCL1,ASPH,ASTN1,ADAM23,TTC9B,ADGRB3,NRP2,BMP7,CDK5R1,ARHGEF7,SCAPER,CACNA1B,CACNA2D1,THSD7A,KALRN,CANX,RUNX1T1,INA,CDH2,CDH10,DCLK1,ZMYM4,LGI1,CLGN,CFL2,CHGB,RAB33A,NRXN3,NRXN2,CNR1,CNTN1,COL9A1,COL9A3,MYRIP,CNRIP1,SLC35F1,FAM171B,CRHBP,CRMP1,HAPLN1,TENM4,SIPA1L1,VCAN,ERC2,PLCXD3,NRSN1,PUM1,GPSM1,KIF26A,TM9SF4,SCRN1,BRINP1,DNAJC6,JAKMIP2,ZNF804A,ZEB2,MFAP3L,TMEM130,NTM,ARNT2,GRIN3A,HS3ST4,CALN1,CPEB2,PDCD6IP,DYRK1A,SEZ6L2,EDNRA,EDNRB,HIPK3,TMTC1,CELSR3,EIF4G1,ELAVL2,ELAVL3,ELAVL4,DCTN4,VPS13B,EPHA5,EPHB1,ETV1,EYA1,NRN1,TMEM132C,TUBB3,CORO2B,DLC1,ATP8A1,SEC24B,KIAA1109,OLFM1,PRKAG2,CAMSAP1,FOXF2,SGIP1,DPYSL4,SMC2,CAMKK2,DACH2,CGREF1,PNMA2,DKK3,MEGF10,GABRA3,CHL1,GABRB1,AHCYL1,IQGAP2,GAP43,SYT17,DNER,GFRA1,GFRA2,PCDH17,PCDH11X,PCSK1N,FERMT2,B4GALNT4,GPR22,RAPGEF4,STMN2,GRIA1,GRIA2,GRM7,KLF12,BACH2,AGBL5,NEGR1,IFI16,DISP2,IL6ST,INSM1,TUBB2B,LRRTM3,JAK1,KCNA6,KCNC2,KCNK2,KCNMA1,KCNQ2,KIF2A,KIF5A,KIF5C,LIFR,LIMS1,MAP4,MAP6,MAPT,MARK1,CHIC1,PPM1L,MMP16,MSI1,RSPO2,NASP,NCAM2,NDP,NEFM,NEK1,NFIA,NFIX,NNAT,NRCAM,HCN1,NTRK2,OPRL1,CLDN11,PIRT,SLC10A4,GPR85,DUSP26,SSH1,NALCN,PIK3C2A,HMGCLL1,PRRX1,MBOAT7,FAT3,MED1,PPP3CA,KANSL1,PRKAR1B,MAPK8,MAPK10,PRPH,BCAS3,SNRK,PTHLH,PTPRG,PTPRO,PTPRZ1,FAT4,RET,REV3L,RGS4,ZFHX4,SETD5,ARMH4,RIMKLA,MEG3,CLIP1,RTN1,RYR3,SCN3A,TNFRSF19,PPP1R9A,NTNG1,ST8SIA1,ANKRD6,SLC8A3,SLC12A2,NAPB,SLC15A2,LGI3,CPEB4,SNAP25,KIF13A,SCN3B,SON,SOX2,SOX11,MYCBP2,ZNF423,KIF1B,NPAS3,C11orf87,CLASP2,EPB41L3,MAPK8IP3,RGL1,STX1A,SYT11,TMEM178B,DNMBP,CAMSAP2,ADGRL3,AGTPBP1,TBL1X,MGRN1,CUX2,PCDHB7,PUM2,HHIP,FBXL16,ASXL3,ZFP91,ERCC6L2,KAT6B,RBFOX2,RGMB,SYNPO2,TRPS1,TMEFF2,RPRM,UCHL1,ZNF23,FMN2,CELF4,FSTL5,WNK1,STMN4,STOX2,FAM13C,NUP214,MSRB3,ST8SIA2" Coexpression Atlas BM Top 100 - amygdala BM Top 100 - amygdala Body Map 2.64E-39 1.35E-35 1.34E-37 1.22E-36 63 73 "SLC12A5,UNC5A,CDK5R1,CACNA1E,KALRN,VSTM2A,CCK,SYNGR3,DLGAP1,CHN1,LHX2,CNR1,GDA,NCAN,ERC2,PLPPR4,AK5,OLFM1,HPCAL4,FOXG1,GABRA1,GABRA2,GABRA5,GABRB1,GABRG2,GAD1,ARPP21,GAP43,RUNDC3A,GPM6A,RAPGEF4,STMN2,GRIA1,GRIA2,PTPN5,WIF1,CELF5,SOWAHA,KCNJ4,KCNQ2,CREG2,C2orf80,MAP2,MAP4,NPTX1,NRGN,OPCML,PCDH8,PDE1A,PACSIN1,SCN2A,FAM19A1,SLC1A2,SLC8A1,SNAP25,SCN3B,DDN,SST,SYN2,SYT1,FBXL16,SLC17A7,SLC17A6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 3.79E-39 1.93E-35 1.89E-37 1.73E-36 203 498 "CPNE2,TTYH1,NCKAP5,KLHL32,ADCYAP1R1,KIAA1324,EPB41L5,APLP1,ASCL1,ATP1A3,ATP2B2,KIF1A,ADGRB3,PROM1,HAP1,PTBP2,CANX,MAP7,INA,CDK11B,CDH2,CDH8,ADGRG1,SRSF11,JAM2,LHX2,KIAA1549L,NRXN2,QKI,NIPBL,IQCK,SLC4A7,SLC4A8,IGDCC3,NECTIN3,SLC35F1,PLCH2,CNTNAP2,FAM169A,ERC2,CTNND2,RIMS2,ST18,KATNAL2,SCRN1,DCC,JAKMIP2,DDX46,SRGAP3,CASP8AP2,MAMLD1,EFNA3,ELAVL2,ELAVL3,ELAVL4,EMX2,OLIG2,RTN3,RRAGB,ADGRV1,REEP2,CLVS1,NSRP1,FABP7,ZIC4,TUBB4A,ATP8A1,SPSB4,FGFR3,FHL1,FOXG1,DLL3,FUT9,B3GAT1,PHYHIPL,ILDR2,SALL3,SRRM4,KIAA1841,PPARGC1A,TCERG1,GLDC,TOX3,MAP7D2,GNAO1,GPM6A,GPM6B,TDRKH,CECR2,PCLO,STMN2,GRIK2,GRIK4,CIT,RNF165,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,HPCA,USP51,HSP90AA1,ATCAY,ZIC5,HES5,INSM1,TUBB2B,KCNN3,KIF5C,KIT,KTN1,LSAMP,MAP2,SHC3,SCG3,RSPO2,MYT1,NASP,NEFM,NELL2,NOVA1,NRCAM,NTRK2,ODF2,GPR137C,PAK3,PAX6,PRTG,FAM98B,SEMA5B,PLP1,SLC25A23,FAT3,POU3F4,IRX1,MAPK10,PROX1,GDPD1,MASP1,GDPD2,ELOVL2,EML5,PTPRZ1,ARID4A,FEZF2,RFX4,CLIP1,RTN1,SAFB,SALL1,LINC00461,ZFP2,SOX6,HSPA4L,SCG5,KIF21A,ARX,FHOD3,NLGN1,SLC1A2,GKAP1,SNAP25,SOX2,BDP1,NPAS3,LMO3,PBLD,NEK4,AJAP1,FGD4,SYNE2,C3orf70,SYN1,MTCL1,WWC1,WSCD1,WASHC4,FRYL,CCDC173,NR2E1,PRMT8,CADM1,FAM181B,MGAT5B,RBFOX3,WNT7A,ZIC1,ZIC2,ZIC3,ZNF23,TRIM9,ZFP41,FMN2,ZBTB16,REEP1,DPYSL5,STMN4,STOX2,TMEM163,FZD3,PRRT4,SPATA13" Coexpression Atlas PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.57E-39 2.84E-35 2.76E-37 2.51E-36 323 979 "TTYH1,ABHD6,GALNT16,ADCY6,ADD2,TXNDC16,ALCAM,SRPX,MRTFA,AMPD2,OGT,SEMA7A,LCORL,CNIH2,APBA2,APBB1,EPB41L5,APLP1,DGKD,VAT1L,STK33,ASPH,ASTN1,ALDH4A1,ATP1A2,CADM3,ATP6V1G2,ATP6V0A1,DOCK11,ADAM23,ADAM15,LINC00847,MPDZ,BCL7A,PROM1,CAST,HIP1R,KYAT1,INA,CDH8,EVI5L,LGI1,CDO1,UBE2L6,CIART,ADGRG1,RCBTB2,CLU,TJP2,CNTFR,SLC25A27,COL9A1,TCEAL2,ZNF521,IGDCC3,NECTIN3,ZNF385A,CPS1,FAM171B,SEC31B,PREPL,AKAP12,CRMP1,HAPLN1,CRY2,CLIP3,DZIP3,PNPLA8,CTNND2,FAM131B,BOC,HDAC9,RIMS3,KIAA0586,ZEB2,HEPH,TMEM130,LYPD1,RHOBTB1,SV2A,ARNT2,DLG4,DMD,CD99L2,CDON,DPYSL2,ARRDC4,EDIL3,TSPAN5,EDN1,KLHL5,CACNG7,MBNL2,RASA4,PLEKHA1,ING4,EMX2,SLC43A2,NCALD,TMEM74,EZH1,REEP2,FABP7,ACSL4,EFEMP1,TESK2,ZNF589,SPSB4,BAIAP2,FHL1,SUCO,SCARA3,UBE2E3,MEX3B,DPYSL4,NBEA,TACC2,TRIM16,GPR153,TPPP3,ZNF512,FYN,ILDR2,FAM184B,FAM120B,IQGAP2,GAP43,TMEM8B,WASF3,GPR162,SESN1,AHDC1,RND1,GLDC,GLI2,TOX3,KIAA1958,LOXL3,GPR19,STON1,LPAR4,GRIK5,LINC01089,SOX21,GUCY1B1,MUM1,IGSF21,CPT1C,ATCAY,MSL1,IFI16,HES5,LIX1,TMEM240,IL11RA,ZNF385B,ITGA7,OLFM3,LRRC4B,LSAMP,CLEC18A,MAP2,MATN2,ADAM11,MEIS2,MEST,SCAMP5,MID1,MPP2,SESN3,CCDC80,MSI1,BCO1,TCEAL5,NAP1L2,NEFM,NELL2,NUMA1,OCRL,KCNK10,PAX6,PBX1,PCDHGC3,PRTG,ENPP2,GPR173,PFKP,CDK14,PGAM2,NLGN3,PCDH18,PLXNB1,SCHIP1,SDK2,POU3F2,FSD1,PPP1R1A,NKAIN4,VSTM2L,CNNM2,BCAS3,LRRC49,PTN,PTPRZ1,OXR1,FEZF2,BEND5,PRRT2,FIGN,RGS10,ARHGEF10L,RIC8B,ZFHX4,PNMA8A,ROBO1,KIRREL1,BAALC,CNTNAP3,HSD11B1L,WLS,YJEFN3,MIR124-2HG,SEC14L1,SCG5,ARX,FNDC3A,FHOD3,NLGN1,ST3GAL3,PKNOX2,SLC6A8,CDK5RAP3,MTERF2,EFHD1,ATF7IP,GKAP1,SMARCC2,SNCA,PALLD,WDTC1,SOX1,SOX2,SOX11,ZSWIM8,SPP1,TSPYL2,COLGALT2,STOX1,SMOC1,LRRC4,ELOVL4,RGL1,PHLDB1,KLHL7,SYT11,SYNE2,VAMP1,ARHGEF9,SYT1,MCF2L,UNC5D,ADGRL3,TBL1X,EHBP1,WSCD1,TCF4,DMXL2,ZFP90,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA3,PCDHB15,PCDHB10,PCDHB9,PCDHB4,PCDHA6,PCDHA5,PCDHA1,AHCYL2,FAM200B,DICER1-AS1,C18orf54,ZMAT3,ZNF106,THBS4,TIAM1,AMACR,FNDC5,SSBP2,TUB,UBE2H,CCDC136,MICAL1,TSPAN11,ELFN1,ATP6V0E2,EMX2OS,CRB2,TCEAL7,ZBTB16,AMZ1,DPYSL5,ZFAND5,MAP3K12,EMSY,GDPD5,TMEM178A,SEMA3B,GAL3ST3,PPP1R3F,CAB39L,TRIM16L,FZD3,MARCH8,KAT6A,SMIM8,TTC7A,PIANP,FRMD6,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 8.47E-38 4.32E-34 4.15E-36 3.79E-35 187 448 "TTYH1,ABAT,SLITRK1,CCDC85A,RNF157,PTCHD1,PCDH10,ANK2,PPFIA2,MAGEE2,SHTN1,SEMA4G,ASCL1,ATP2B2,CADM3,CARMIL3,JAZF1,SGCE,DIRAS1,HAP1,VSTM2A,CDC25B,EVI5L,NUMBL,ADGRG1,SRSF11,FOXN3,SLIT2,NRXN3,DNAJB5,IGLON5,ARHGEF6,WHRN,COL4A5,SLC25A27,LETMD1,AATK,CSF1,NCAN,CNTNAP2,SLITRK5,PPP6R2,ST18,RUBCN,PYGO1,PHF19,SCRN1,BRINP1,DNAL1,DCC,MYEF2,RUSC2,FBXO25,SV2A,SRGAP3,ARNT2,DLX1,CD99L2,SHANK1,DTNA,EDNRB,FSD1L,ELAVL3,TMEM35A,OLIG2,ENO2,EPHB1,APC2,ADGRV1,FABP7,TUBB3,CHST15,FOXG1,SEMA6C,DPYSL4,SPECC1,NSG1,NRG3,GAD1,GAD2,SRRM4,ACSS1,FAXC,PCDH11X,GPM6A,GPM6B,DIPK1C,STMN2,GRIK2,CACFD1,NR3C1,RNF165,MFSD2A,CELF3,TOX2,FRMD5,KLF12,IGFBPL1,CPT1C,CELF5,ATCAY,EID2B,HES5,BRINP3,MAP2,MARK1,MBP,SHC3,TAGLN3,SAMD14,LINC00672,MYT1,NELL2,NFIA,NRCAM,PGAM2,NLGN3,SMOX,SLC36A4,POU3F4,POU6F1,TATDN3,PPP3CC,PKIA,EPDR1,MAPK10,GDPD1,RAB3A,RFX5,MEG3,RTN1,CSRNP3,LRRTM4,LINC00461,HSPA4L,SCG5,SLC1A3,FAM214B,MAST1,SORCS3,SMARCD3,RCOR3,SNAP25,MAPKBP1,SOX5,LHFPL4,NPAS3,CLSTN2,NKAIN2,DIP2A,SEPT3,GSE1,FAM168A,KLHL7,SYT11,RHBDL3,SYP,ASTN2,SEMA4A,TMEM178B,ACSL6,CUX2,AZIN2,TMEM151B,PSD3,AHCYL2,THRA,DDHD1,TRPC3,KCNE5,SSBP2,TUB,TUBB2A,MGAT5B,PLPPR2,TSPAN11,NPDC1,ZIC1,ZIC3,DPYSL5,SHD,STMN4,STOX2,TUBA1A,WNK2,FZD3,SENP7" Coexpression Atlas BM Top 100 - parietal lobe BM Top 100 - parietal lobe Body Map 3.86E-37 1.97E-33 1.88E-35 1.71E-34 63 76 "SLC12A5,ERMN,UNC5A,SYT13,CDK5R1,KALRN,VSTM2A,CCK,SYNGR3,DLGAP1,CHN1,LHX2,KIAA1549L,NGEF,CABP1,GDA,RIMS3,SV2B,ELAVL2,ELAVL4,OLFM1,FOXG1,GABRA1,GABRA4,GABRG2,GAD1,GAP43,CPLX1,STMN2,GRIA2,WIF1,CELF5,HTR2A,KCNJ4,KCNMA1,KCNQ2,CREG2,C2orf80,MAP4,MOBP,NEFM,NPTX1,NRGN,HCN1,OPCML,PCDH8,PDE1A,SERPINI1,PRKCB,DIRAS2,RGS4,SCN2A,SLC1A2,SLC8A1,SNAP25,SCN3B,C11orf87,SST,SYN2,SYT1,TAC1,VSNL1,SLC17A7" Coexpression Atlas BM Top 100 - occipital lobe BM Top 100 - occipital lobe Body Map 4.08E-37 2.08E-33 1.96E-35 1.79E-34 62 74 "SLC12A5,ERMN,UNC5A,SYT13,ATP2B2,KALRN,VSTM2A,CCK,DLGAP1,CDR1,CHN1,LHX2,NGEF,CABP1,GDA,RIMS3,ELAVL2,ELAVL4,OLFM1,FOXG1,GABRA1,GABRA2,GABRA4,GABRG2,GAD1,ARPP21,GAP43,CPLX1,GPM6A,STMN2,GRIA2,WIF1,CELF5,HTR2A,KCNQ2,CREG2,C2orf80,MAP4,MOBP,NPTX1,NRGN,HCN1,OPCML,PCSK1,SERPINI1,DIRAS2,RGS4,RORB,SCN2A,SLC1A2,RPH3A,SLC8A1,SNAP25,SNRPN,C11orf87,SST,SYN2,SYT1,TAC1,CUX2,VSNL1,SLC17A7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 4.53E-37 2.31E-33 2.16E-35 1.97E-34 240 655 "DPF1,ABCF1,SYN3,ACLY,ABHD6,NCKAP5,FMNL2,KLHL32,GALNT16,MTUS1,PCDH19,SEMA6A,ALCAM,LTBP4,GPRASP2,CDC42BPA,EPB41L5,APLP1,PHYHD1,LRRC4C,MADD,RGS20,NCOA1,ASTN1,ATP6V1G2,KIF1A,ADAM23,ADGRB3,PROM1,BMPR1B,DST,CACNA1A,CACNA2D1,THSD7A,PTBP2,CDK11B,LONRF2,CDH2,CDH8,MAGI1,DIS3L,JAM2,LHX2,KIAA1549L,NRXN1,NRXN2,CLTB,C4orf33,CNTFR,IQCK,SLC4A8,IGDCC3,SLC35F1,FAM171B,CREB5,CLIP3,CSF2RA,FEZ1,ATRNL1,FAM169A,ERC2,PHF14,CTNND2,RIMS2,BOC,KATNAL2,TOX,DGKB,JAKMIP2,DDX46,RAB39B,DMD,CASP8AP2,MAMLD1,CACNG7,EFNA3,PLXNC1,EIF5,ELAVL2,CERCAM,ELAVL4,RGS17,BSCL2,C8orf37,EMX2,LRRC23,EPHA5,GPHN,DENND4A,FAM198B,ACSL4,TAOK3,CORO2B,ATP8A1,FDFT1,MED12L,FGF12,FGFR3,FHL1,NBEA,KHDRBS3,FUT9,B3GAT1,ADGRA1,TPPP3,PHYHIPL,GABRB3,ILDR2,KIAA1841,GATM,GFRA1,PPARGC1A,DBF4,TOX3,MAP7D2,GNAO1,GNG3,TDRKH,PCLO,GRIK4,CIT,RABL2A,SOX21,LINGO1,DDX19B,HPCA,USP51,NEGR1,IGSF1,INSM1,TUBB2B,LRRTM1,KCNN3,CREG2,KIF5C,KTN1,LSAMP,LSS,TM6SF1,MEIS2,CD200,ADAM22,MSR1,NRBP2,N6AMT1,SCG3,MXI1,NASP,NCAM1,NCAM2,NEFM,NOVA1,NTRK2,NUCB2,ODF2,OPA1,GPR137C,PAK3,PAX6,PCDH9,PDE1A,PDE3B,SEMA5B,ZFYVE21,TMEM38A,GPSM2,SLC25A23,TRHDE,MAPKAP1,FAT3,CRLS1,VPS13C,MDGA2,ELOVL2,PTPRD,EML5,PTPRZ1,FAT4,ENOX1,FEZF2,RBBP6,RBBP8,PRRT2,RFX4,FBXW7,TCP11L1,STX1B,CCDC112,SAFB,ATXN1,SOX6,ZFP30,KIF21A,PPP1R9A,PPM1E,ARX,FHOD3,NLGN1,GKAP1,DOP1A,TRERF1,GLT8D1,NPAS3,LMO3,LARP4,ZSCAN29,FGD4,SYNE2,VPS13A,SYN1,ANKRD28,ATP11A,ANKRD12,CCDC173,AKTIP,NACC2,NR2E1,KAT6B,NR2C2,PRMT8,STXBP4,FLRT1,FAM181B,USP1,RBFOX3,WNT7A,ZNF23,TRIM9,FMN2,LYPD6,CELF4,ZBTB16,REEP1,SPIRE1,LRP8,GAL3ST3,TMEM163,KLHDC1,NETO2,ST8SIA2" Coexpression Atlas PCBC_ratio_EB_from-plasmid_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-method_plasmid_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 7.66E-37 3.91E-33 3.62E-35 3.30E-34 80 115 "DPF1,ADCYAP1R1,DISP3,ANK2,CNIH2,ATP1A3,CADM3,CDK5R1,CACNA2D1,THSD7A,BRSK2,CBLN1,INA,DCLK1,CRLF1,ADGRG1,RAB3C,CLCN4,CNR1,CTNND2,KIAA0408,BRINP1,FAM57B,EBF1,EDNRB,LINC00599,ELAVL2,ELAVL3,ELAVL4,APC2,TUBB3,OLFM1,FGF13,NSG2,GPR153,PHYHIPL,GAP43,CPLX2,DNER,C1QL1,RUNDC3A,GPM6B,C1QL4,CELF3,UBE2QL1,ARHGAP19,IGFBPL1,ATCAY,SCRT2,INSM1,KIF5A,KIF5C,MAP2,MAPT,SCG3,MYT1,NCAM1,NHLH1,NOVA2,GDAP1L1,PTPRN,RTN1,LINC00461,HES6,LRRC55,SLIT1,SNAP25,KIF21B,NMNAT2,NFASC,NACAD,SEPT3,ROBO3,CNTN2,RGMB,FNDC5,MGAT5B,STMN4,TMEM163,SLC17A6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.75E-36 8.94E-33 8.20E-35 7.47E-34 86 131 "CSMD3,ADCYAP1R1,VAT1L,SLC7A14,CADPS,CADM3,KIF1A,ADAM23,TTC9B,ADGRB3,NRP2,INA,DCLK1,LGI1,CHGB,RAB33A,FAM171B,CRMP1,FEZ1,PLXNA4,NRSN1,SCRN1,SV2A,DLG2,EBF1,EDNRB,ELAVL2,ELAVL4,EYA1,FABP7,TUBB3,FDFT1,FGF13,NSG1,PHYHIPL,GAP43,SYT17,IGSF5,GFRA1,C1QL1,GLRB,GNAO1,STMN2,GRIA2,DISP2,LIX1,KIF5C,L1CAM,SYTL4,LSAMP,MAP6,ADAM22,SCG3,DDX25,NCAM1,NEFM,NELL2,NNAT,NOVA1,NTRK3,SLC10A4,PFKP,GDAP1L1,SERPINE2,MAPK10,EML5,RET,RTN1,FAM19A1,SCG5,SNAP25,SNRPN,SCN3B,EPB41L3,SEPT3,SYT11,NUDT10,SYP,SYT1,ASTN2,CUX2,PCDHB9,TMEFF2,CADM1,DPYSL5,STMN4" Coexpression Atlas BM Top 100 - cerebral cortex BM Top 100 - cerebral cortex Body Map 2.11E-36 1.08E-32 9.70E-35 8.84E-34 61 73 "SLC12A5,ERMN,UNC5A,ATP2B2,KALRN,VXN,VSTM2A,CCK,DLGAP1,CDR1,CHN1,LHX2,NGEF,CABP1,GDA,RIMS3,OLIG1,ELAVL2,ELAVL4,OLFM1,FOXG1,GABRA1,GABRA2,GABRG2,GAD1,ARPP21,GAP43,CPLX1,STMN2,GRIA2,PTPN5,WIF1,CELF5,HTR2A,KCNJ4,KCNQ2,CREG2,C2orf80,MAP4,MOBP,MOG,NPTX1,NRGN,HCN1,OPCML,PDE1A,ANLN,DIRAS2,RGS4,SCN2A,SLC1A2,SLC8A1,SNAP25,SNRPN,SCN3B,SST,SYN2,SYT1,TAC1,VSNL1,SLC17A7" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K4 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 2.11E-36 1.08E-32 9.70E-35 8.84E-34 126 247 "TTYH1,GALNT16,RNF157,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,LRRC4C,NCOA1,ASTN1,CADM3,ADAM23,CARMIL3,ADGRB3,JAZF1,CACNA1A,VSTM2A,LONRF2,CDH8,EVI5L,FOXN3,SLIT2,LHX2,KIAA1549L,NRXN1,IGLON5,IQCK,WHRN,SLC4A8,IGDCC3,SLC35F1,CREB5,AATK,CSF2RA,FEZ1,ERC2,TOX,DGKB,SCRN1,DCC,RUSC2,DMD,SHANK1,DTNA,MAMLD1,EFNA3,RGS17,TMEM35A,ENO2,LRRC23,EPHA5,APC2,CEND1,CHST15,FGF12,DPYSL4,TPPP3,NRG3,ACSS1,PCDH17,CSDC2,PPARGC1A,PCDH11X,GPM6B,NR3C1,MFSD2A,NEGR1,BRINP3,KCNN3,ADAM22,NRBP2,TAGLN3,NCAM1,NCAM2,NELL2,NFIA,NTRK2,GPR137C,PCDH9,PDE1A,NLGN3,SEMA5B,TMEM38A,FAT3,POU6F1,MAPK10,MDGA2,PTPRD,ENOX1,PRRT2,MEG3,STX1B,ATXN1,LRRTM4,NTNG1,NLGN1,SLC1A3,FAM214B,MAST1,SMARCD3,NPAS3,CLSTN2,DIP2A,RHBDL3,SYP,ASTN2,SEMA4A,TMEM178B,CUX2,TMEM151B,PSD3,THRA,NR2E1,SSBP2,TUB,ZIC1,TRIM9,FMN2,LYPD6,CELF4,STMN4,TMEM163,WNK2,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-35 1.11E-31 9.85E-34 8.98E-33 104 184 "KIDINS220,ANK2,ANK3,APLP1,CADPS,RNF182,CDK5R1,GPC2,THSD7A,RUNX1T1,INA,SEPT7,DCLK1,NRXN1,AKAP6,CRMP1,FEZ1,NCAN,KIAA0408,TOX,KIF26A,CEP170,ARNT2,DPYSL2,EDIL3,ATL1,ELAVL2,ELAVL3,ELAVL4,EMX2,NRN1,TUBB3,MEX3B,NSG2,NSG1,PHYHIPL,GABRB3,GAP43,SRRM4,GNG3,GPM6A,CCDC184,STMN2,GRIA2,GRIK2,KIF3A,UBE2QL1,KLF12,SHISA6,ATCAY,TUBB2B,KCND2,KIF5C,KLC1,L1CAM,STMN1,MSANTD3-TMEFF1,MAP6,CD200,SCG3,TAGLN3,NCAM1,NEFM,NNAT,NOVA1,PBX1,PCSK2,GNG2,GDAP1L1,SCHIP1,LRRN3,MAPK8,LRRC49,PTPRO,ZFHX4,RTN1,AMER2,CSRNP3,SCN3A,CHD9,SYBU,SLC1A2,SORCS3,KIF21B,SOX11,NMNAT2,CLASP2,POGZ,SEPT3,SYT1,KIAA1107,RALYL,ASXL3,RBFOX2,TTC3,TUBB2A,UCHL1,PLPPR2,CELF4,DPYSL5,STMN4,TUBA1A,SLC17A6,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.18E-35 1.11E-31 9.85E-34 8.98E-33 104 184 "KIDINS220,ANK2,ANK3,APLP1,CADPS,RNF182,CDK5R1,GPC2,THSD7A,RUNX1T1,INA,SEPT7,DCLK1,NRXN1,AKAP6,CRMP1,FEZ1,NCAN,KIAA0408,TOX,KIF26A,CEP170,ARNT2,DPYSL2,EDIL3,ATL1,ELAVL2,ELAVL3,ELAVL4,EMX2,NRN1,TUBB3,MEX3B,NSG2,NSG1,PHYHIPL,GABRB3,GAP43,SRRM4,GNG3,GPM6A,CCDC184,STMN2,GRIA2,GRIK2,KIF3A,UBE2QL1,KLF12,SHISA6,ATCAY,TUBB2B,KCND2,KIF5C,KLC1,L1CAM,STMN1,MSANTD3-TMEFF1,MAP6,CD200,SCG3,TAGLN3,NCAM1,NEFM,NNAT,NOVA1,PBX1,PCSK2,GNG2,GDAP1L1,SCHIP1,LRRN3,MAPK8,LRRC49,PTPRO,ZFHX4,RTN1,AMER2,CSRNP3,SCN3A,CHD9,SYBU,SLC1A2,SORCS3,KIF21B,SOX11,NMNAT2,CLASP2,POGZ,SEPT3,SYT1,KIAA1107,RALYL,ASXL3,RBFOX2,TTC3,TUBB2A,UCHL1,PLPPR2,CELF4,DPYSL5,STMN4,TUBA1A,SLC17A6,ST8SIA2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.06E-35 1.56E-31 1.37E-33 1.25E-32 256 735 "ASPHD1,SYN3,CSMD3,NDRG2,ADCYAP1R1,SORCS1,MTUS1,LRRC7,SPARCL1,PCDH10,UNC79,ANK2,C6orf89,APBA2,VAT1L,SLC7A14,CADPS,ASCL1,CADM3,ATP6V0A1,KIF1A,ADAM23,ADGRB3,NRP2,C1QC,CACNA1B,CACNA1E,INA,LONRF2,DCLK1,LARGE1,CDO1,CHGB,RAB3C,SLIT2,RAB33A,NRXN3,NRXN1,CLTB,PICK1,CNTFR,FAM171B,CRHBP,CREB5,CRMP1,CLIP3,FEZ1,ATRNL1,VCAN,CST3,PLXNA4,ERC2,CMTM5,PLCXD3,NRSN1,RIMS2,DGKB,SCRN1,BRINP1,DCC,DNAJC6,JAKMIP2,SNAP91,SPOCK3,DLG2,GRIN3A,MED12,DRP2,ABCC9,EBF1,EDNRA,EDNRB,ATL1,TMTC1,FRY,EGFR,ELAVL2,ELAVL4,LRRC17,DENND4A,NCALD,CEND1,EYA1,CLVS1,FABP7,TUBA1B,TUBB3,TUBB4A,EFEMP1,ATP8A1,RACK1,CHST15,FDFT1,KIAA1109,FGF13,FGF14,SGIP1,NOP56,NSG2,NSG1,TPPP3,GABBR1,GABRB3,GAP43,SYT17,ATP8A2,IGSF5,GFRA1,GFRA2,FREM1,RAB30,GLRB,GNAO1,GNG3,GPR19,TUBA1C,STMN2,GRIA1,GRIA2,GRIK2,PTPRT,GSTM5,ADAMTS6,CELF3,KLF12,ARHGAP36,ACOT7,HPSE2,HMGCR,IGF1,DISP2,LIX1,TUBB2B,KCNMA1,KIF5A,KIF5C,KIT,L1CAM,LAMA2,INSYN2,LMO1,SYTL4,LSAMP,MAOB,MAP6,MATN2,MEIS1,MEIS2,MMP16,ADAM22,SCG3,TAGLN3,RSPO2,MYH3,MYT1,NCAM1,NEFM,NELL1,NELL2,NFIX,NNAT,NPY,NOVA1,PCBP3,NRCAM,NTRK2,NTRK3,DDR2,PCDH9,PDE3A,PDGFRA,ENPP2,SLC10A4,PENK,TMOD2,PFKFB2,PFKP,GDAP1L1,SERPINE2,NALCN,FXYD1,PCDH18,PMP22,PRRX1,FAT3,POLR2F,PPP1R1A,PPP2R2B,NKAIN4,MAPK10,PROX1,PRPH,MASP1,PTN,STK32A,EML5,TMEM255A,C1orf54,FAT4,ENOX1,ZMAT4,RET,RGS4,LGI2,ROBO2,ARMH4,CNTNAP3,HUNK,RTN1,RYR3,S100B,SCN2A,SCN3A,SCN7A,FAM19A1,SCG5,SH3GL3,SLC8A1,SNAP25,SNCA,SNRPN,PALLD,UNC80,SCN3B,NMNAT2,THSD1,SST,EPB41L3,SULF2,SEPT3,SYT11,SYP,SYT1,SYT4,ASTN2,ADGRL3,AGTPBP1,CUX2,TEK,TF,ASXL3,TNNT1,TNR,TPM2,SSBP2,TUBB2A,TMEFF2,CADM1,UCHL1,VLDLR,NPDC1,ZNF32,STMN4,TUBA1A,ADAMTS9,ST7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.16E-35 1.61E-31 1.40E-33 1.28E-32 140 298 "CPNE2,NCKAP5,FMNL2,KLHL32,PLEKHH1,KIAA1324,TAOK1,EPB41L5,APLP1,PHYHD1,NCOA1,ASTN1,KIF1A,ADAM23,ADGRB3,PROM1,CACNA1A,PTBP2,CDK11B,CDH2,MAGI1,FOXN3,JAM2,LHX2,KIAA1549L,NRXN2,CLTB,QKI,IQCK,SLC4A7,SLC4A8,ACBD5,IGDCC3,NECTIN3,SLC35F1,FAM171B,CSF2RA,CNTNAP2,SLITRK5,ERC2,CTNND2,RIMS2,ST18,KATNAL2,KIAA0586,JAKMIP2,FBXO25,DDX46,SRGAP3,RAB39B,DMD,CASP8AP2,MAMLD1,EFNA3,PLXNC1,ELAVL2,ELAVL4,RGS17,TMEM35A,EMX2,EPB41,LRRC23,NSRP1,FGFR3,ZNF605,FUT9,B3GAT1,PHYHIPL,ILDR2,KIAA1841,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,GPM6A,TDRKH,PCLO,CIT,MFSD2A,SOX21,DDX19B,USP51,TUBB2B,KCNN3,KIF5C,KTN1,TM6SF1,PPM1L,SCG3,NASP,NEFM,NELL2,NOVA1,NTRK2,ODF2,GPR137C,PAK3,SEMA5B,SLC25A23,TRHDE,FAT3,PROX1,GDPD1,MDGA2,ELOVL2,PTPRD,EML5,FAM184A,ARID4A,FEZF2,PRRT2,RFX4,CLIP1,RTN1,LINC00461,SOX6,HSPA4L,KIF21A,PPM1E,ARX,FHOD3,SNAP25,NPAS3,DIP2A,FGD4,SYNE2,SYN1,TCF7L2,CCDC173,TJP1,NR2E1,PRMT8,SLAIN1,FMN2,LYPD6,REEP1,STOX2,GAL3ST3,ST8SIA2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.89E-35 2.50E-31 2.15E-33 1.96E-32 83 127 "CSMD3,SLITRK1,RNF157,DPP10,SLC7A14,CADPS,ASCL1,ASTN1,ADGRB3,CACNA1B,INA,CDH10,CHGB,CNR1,CNTN1,AKAP6,MYRIP,FAM171B,PLCXD3,NRSN1,ST18,DGKB,SCRN1,JAKMIP2,ZNF804A,SNAP91,GRIN3A,CALN1,EBF1,EDIL3,ST8SIA3,ELAVL2,ELAVL4,FABP7,TUBB3,ATP8A1,FGF13,GAP43,SYT17,GFRA2,GPR22,STMN2,GRIA1,GRM7,FAM19A2,INSM1,KCNQ2,KIF5C,SYTL4,MAP2,MAP4,MAPT,RSPO2,NCAM2,NDP,NEFM,NOVA1,NTRK2,CLDN11,CNTN3,SLC10A4,GPR85,DUSP26,SERPINI1,NALCN,MAPK10,PRPH,EML5,PTPRO,RBBP6,RGS4,RTN1,SCN3A,CXXC4,SNAP25,SCN3B,C11orf87,SYT11,SYT4,CUX2,CADM1,FSTL5,STMN4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.18E-34 6.01E-31 5.13E-33 4.68E-32 116 223 "TTYH1,RNF157,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,ASCL1,NCOA1,ASTN1,ADAM23,ADGRB3,BMPR1B,JAZF1,CACNA1A,VSTM2A,LONRF2,CDH8,EVI5L,SRSF11,SLIT2,LHX2,KIAA1549L,NRXN1,CLTB,IGLON5,ARHGEF6,SLC4A8,IGDCC3,SLC35F1,CREB5,AATK,CSF2RA,FEZ1,ERC2,HDAC9,TOX,SCRN1,RUSC2,DMD,SHANK1,DTNA,MAMLD1,TMEM35A,EMX2,ENO2,EPHA5,APC2,CHST15,FOXG1,DPYSL4,TPPP3,NRG3,ACSS1,GATM,PPARGC1A,GPM6B,GRIK2,MFSD2A,NEGR1,BRINP3,KCNN3,MEIS2,ADAM22,MSR1,NRBP2,TAGLN3,NEXMIF,NCAM2,NELL2,NTRK2,PCDH9,PDE1A,NLGN3,SEMA5B,TMEM38A,FAT3,POU6F1,MAPK10,MDGA2,PTPRD,ENOX1,FEZF2,PRRT2,STK32B,MEG3,RTN1,STX1B,ATXN1,LRRTM4,NTNG1,NLGN1,SLC1A3,MAST1,SMARCD3,NPAS3,CLSTN2,DIP2A,RHBDL3,SYP,ASTN2,SEMA4A,TMEM178B,CUX2,FAM189A1,PSD3,THRA,NR2E1,FMN2,LYPD6,LRP8,STMN4,WNK2,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.98E-34 1.01E-30 8.55E-33 7.79E-32 312 979 "DPF1,TTYH1,NCKAP5,SLITRK1,ADCYAP1R1,PLEKHH1,KIAA1211,PCDH10,PHF12,PKP4,APBB1,EPB41L5,SHTN1,MIER1,ARRB2,ASCL1,DACT3,PTCH2,NUMB,ATP1A3,ATP2B2,KIF1A,ADAM15,BBS2,MPDZ,SEC11C,BLM,PROM1,FOXK1,DDR1,DIRAS1,HAP1,CBLN1,INA,CD81,CDH2,CDH8,ARHGAP33,LRWD1,ADGRG1,SRSF11,CNOT8,JAM2,LHX2,NRXN3,NRXN2,COG1,CLTA,QKI,PCYT1B,IGDCC3,SLC35F1,CRMP1,CSNK1E,NCAN,CNTNAP2,SLITRK5,CTNND2,RIMS2,ST18,SCRN1,CTIF,DBN1,DCC,JAKMIP2,ELMO1,SRGAP3,KBTBD11,DLX1,RAB39B,DTNA,MAMLD1,DYRK1A,ST8SIA3,EDNRB,KLHL5,FSD1L,RBM12,PLXNC1,ELAVL2,PLEKHA1,ELAVL3,ELAVL4,OLIG2,MTSS1L,SEZ6,EPHB1,SRRM1,APC2,PIPOX,RTN3,ADGRV1,GMPR2,ECSIT,REEP2,CLVS1,WAC,FABP7,ZIC4,TUBB3,TUBB4A,RACK1,FOXG1,FOXM1,AFF2,DPYSL4,POMT1,NSG2,DLL3,FUT9,B3GAT1,MSANTD4,OGA,FYN,PHYHIPL,NEURL4,GABRB3,ILDR2,GAD1,GAD2,BRPF3,SALL3,IQGAP2,GAP43,C15orf41,SRRM4,ACSS1,KIAA1841,NFU1,PPARGC1A,RUNDC3A,TXNL4A,COPS8,GLDC,TOX3,MAP7D2,DCLK2,GNG3,GOLGB1,GPM6A,GPM6B,TDRKH,STON1,CECR2,PCLO,STMN2,GRIK2,GRIK3,PRDM5,RNF165,GSTM5,MFSD2A,SOX21,FAM222A,CELF3,HPS5,TOX2,FRMD5,IGFBPL1,USP51,CELF5,ATCAY,SHISAL1,HES5,INSM1,TUBB2B,LRRTM3,KCNH2,KIF5C,LRRC4B,PAXBP1,LSAMP,MAP2,MARK1,MBP,SHC3,PPM1L,MSI1,BCO1,SCG3,TAGLN3,MYCN,MYT1,NELL2,NNAT,NOVA1,NRCAM,GPR137C,PAK3,PCMT1,TMOD2,GDAP1L1,SSH1,SEMA5B,PRIMPOL,POU3F4,KANSL1,MAPK10,PROX1,GDPD1,ELOVL2,EML5,C1orf109,PTPRZ1,PPP2R3C,ARID4A,GAL3ST4,ZYG11B,RFX4,KIF7,SETD5,SOX8,ST6GALNAC6,CLIP1,RTN1,SALL1,MAPK12,LINC00461,ZFP2,SOX6,CASC3,GALNT10,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,ARX,SLC1A2,FAM81A,SEPHS1,SLC12A2,CXXC4,MAST1,CDK5RAP2,SNAP25,SNRPN,SOX2,SPATA7,SOX11,LHFPL4,KIF1B,NPAS3,MPRIP,STAU1,GSE1,ACSBG1,SYT11,SYNE2,SYN1,SYP,MMS19,TACC1,ROBO3,MCF2L,TAF9,TMEM178B,WWC1,TCEA1,WSCD1,ACSL6,CUX2,ZEB1,WASHC4,USP22,CLASP1,ARHGEF12,FRYL,SIRT1,TIAM1,HEY1,BHLHB9,NR2E1,TP53BP1,AMACR,TRO,CA14,TUB,ZKSCAN5,UCHL1,SLAIN1,FAM181B,BCL2L13,MGAT5B,RBFOX3,CLIP2,WNT7A,ZIC1,ZIC3,ZNF711,ZFP41,CELF4,REEP1,TMEM198,ZNF189,DPYSL5,ZFAND5,MEIS3,WNK1,STMN4,STOX2,PCBP4,WNK2,FZD3,KAT6A,HNRNPA3,PHTF2,RSPRY1,ZDHHC20,FRMD6,GAN,SPATA13" Coexpression Atlas BM Top 100 - midbrain BM Top 100 - midbrain Body Map 2.61E-34 1.33E-30 1.12E-32 1.02E-31 59 72 "SLC12A5,ERMN,PLEKHH1,CARNS1,SYT13,CADPS,SYNJ2,CALB2,CAPN3,VXN,INA,SYNGR3,CHGB,MAP4K4,ST18,SPOCK3,OLIG1,CALN1,ELAVL2,ELAVL4,OLIG2,FGF1,GABRG2,GFAP,MAP7D2,CNDP1,GPR37,STMN2,KCNJ16,MAG,MAP4,MBP,MOBP,MOG,NEFM,NEFH,CDK18,ANLN,TMEM235,KLK6,QDPR,PAQR6,S100B,SCN2A,FAM19A1,NAPB,SNAP25,SPP1,SYT1,TF,SPX,UGT8,SLAIN1,VSNL1,P2RY12,CLDND1,ZIC2,FSTL5,SLC17A6" Coexpression Atlas BM Top 100 - subthalamic nucleus BM Top 100 - subthalamic nucleus Body Map 3.04E-34 1.55E-30 1.29E-32 1.18E-31 57 68 "ERMN,PLEKHH1,CARNS1,BCAS1,AQP4,SYNJ2,MYRF,CAPN3,VXN,SLC5A11,PLEKHB1,MAP4K4,CMTM5,ST18,CX3CR1,RASSF2,SPOCK3,OLIG1,CERCAM,OLIG2,FGF1,GALNT15,GFAP,CNDP1,GPR37,HAPLN2,TTYH2,MAG,MBP,MOBP,MOG,NKX2-2,OLR1,CLDN11,CDK18,ANLN,PMP2,FA2H,TMEM235,KLK6,TMEM206,GLDN,PAQR6,S100B,AMER2,SLCO1A2,SPP1,NKAIN2,CNTN2,TF,SPX,SLC44A1,PRR18,UGT8,SLAIN1,P2RY12,CLDND1" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K1 facebase_RNAseq_e10.5_Emin_MedNas_2500_K1 Gudmap RNAseq 3.34E-34 1.70E-30 1.41E-32 1.28E-31 330 1060 "DPF1,ABCF1,NCKAP5,ARID1A,CCDC85A,SORCS1,KIAA1211,KLHL13,OSBPL1A,KIAA1324,CEP126,LRCH2,ANK2,USP28,APC,EPB41L5,MAGEE2,VAT1L,LGR5,MADD,ARHGAP5,ARRB2,CADPS,CAPRIN2,PTCH2,ASTN1,ATM,CADM3,ATP6V1G2,KIF1A,ADGRB2,BLM,ZNF599,PROM1,ST3GAL5,ARHGEF7,FUBP1,WASF1,CFAP410,CA4,CACNA1A,THSD7A,PTBP2,CH25H,BRSK2,PRC1,SHISA7,USP2,CBFA2T2,CDK11B,CDH2,KCNAB3,CACNA2D2,ADGRG1,FOXN3,CHN1,SLIT2,KIAA1549L,NRXN1,C4orf33,QKI,NIPBL,IGLON5,CNR1,CNTFR,SLC4A7,SLC4A8,MYRIP,NECTIN3,SLC35F1,FAM171B,CRMP1,CRY2,CLIP3,CSF3R,CNTNAP2,FAM169A,PPP1R16B,PHF14,GREB1,CTNND2,FGFR1OP2,KATNAL2,RIPOR2,TOX,RASSF2,LIN54,KIAA0586,CTIF,DNAJC6,DDX46,SRGAP3,ARNT2,DLG4,DMD,USP3,CASP8AP2,DPP6,DTNA,FAM78B,MAMLD1,WDPCP,FSD1L,EIF4G2,C8orf37,EPB41,CDKL3,CEND1,EXTL2,KATNAL1,REEP2,WAC,TUBB4A,CORO2B,SPSB4,CAMSAP1,FHL1,DPYSL4,SMC2,ZNF605,PRELID3A,DACH2,CSPG5,FUT9,NRG3,PHYHIPL,GABRA1,GABRA3,IP6K3,IQGAP2,TMEM8B,MTHFD2,SYT17,C15orf41,WASF3,KIAA1841,TUBGCP4,ADAM28,GFRA2,GGT7,PPARGC1A,RUNDC3A,GK,GLDC,DBF4,GLRB,TOX3,CBX1,KIAA1958,GNAO1,GNG3,GPM6A,GPM6B,GPR19,GRK4,CNTRL,STMN2,CIT,MFSD2A,PSIP1,FAM107A,RNFT2,FRMD5,HMGCR,HPCA,HSF2,HSP90AA1,SMAP1,SHISAL1,DOCK7,LRRCC1,LIX1,TUBB2B,LRRTM3,KCNC1,KCNH2,KCNJ16,KIF2A,KIT,LRRC4B,SFXN5,HECTD2,LSAMP,LSS,MARK1,SYT9,MID1,PPM1L,MSI1,NRBP2,TAGLN3,MDGA1,SAMD14,MYCN,LYRM9,LINC00672,MYO5A,NEXMIF,NASP,RCOR2,NOVA2,KSR2,ODF2,PAK3,PDE3B,PDE1B,TMOD2,FAM98B,SEMA5B,PIK3CD,SNX10,GPSM2,SLC25A23,ZNF426,SPATA6,FAT3,PKIA,PRKAR1B,MAPK4,MAPK8,PROX1,GDPD1,RELN,SLC22A23,LAMA1,GDPD2,MDGA2,CNTLN,PTCH1,ELOVL2,SPDL1,ZIK1,EML5,PTPRO,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,VEPH1,ERI2,RFX3,RNASEL,SETD5,MYH14,CCDC25,RIMKLA,KCNIP3,CLIP1,RTN1,STX1B,LRRTM4,SCN8A,ELMOD1,ZFP2,SOX6,SELL,SFPQ,KIF21A,PPM1E,CHD9,FHOD3,CCDC92,NLGN1,ST8SIA1,ANKRD6,DHX30,WDR47,PKNOX2,CCDC88A,ZNF334,CXXC4,SMARCE1,SCN3B,SOX5,SPATA7,SOX11,ERC1,ZNF423,ZC3H13,CLSTN2,ZSCAN29,NEK4,SEPT3,SYT11,SYNE2,VPS13A,C3orf70,SYT5,CAMTA1,CUX2,ZEB1,TCF12,CLASP1,SIRT1,AKTIP,NACC2,R3HDM1,PIK3R5,TP53BP1,PRMT8,STXBP4,TRPS1,SLAIN1,FAM181B,USP1,NSD2,WNT7A,KLC2,ZFP37,ZNF711,ZNF23,ZFP41,AGMO,REEP1,ZNF184,EML6,SMARCAD1,EMSY,LRP8,STOX2,TUBA1A,GAL3ST3,FIP1L1,WNK3,WNK2,FZD3,NETO2,ST8SIA2,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000_K2 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.75E-34 2.42E-30 1.99E-32 1.81E-31 111 210 "NCKAP5,PLEKHH1,PCDH19,LTBP4,GPRASP2,EPB41L5,SHTN1,ASCL1,ASTN1,PROM1,DIRAS1,HAP1,LONRF2,ADGRG1,SRSF11,LHX2,NRXN3,KIAA1549L,NRXN1,IGDCC3,CREB5,FEZ1,CNTNAP2,ST18,TOX,RUSC2,DMD,SHANK1,DTNA,MAMLD1,ELAVL2,ELAVL3,ELAVL4,RGS17,TMEM35A,EMX2,EPB41,EPHA5,APC2,ADGRV1,ACSL4,TUBB3,CHST15,FHL1,FOXG1,KHDRBS3,FUT9,NRG3,PHYHIPL,ILDR2,GAD1,SRRM4,KIAA1841,PPARGC1A,GLDC,TOX3,MAP7D2,PCLO,MFSD2A,SOX21,FAM222A,TOX2,FRMD5,IGFBPL1,NEGR1,HES5,KCNH2,KTN1,MBP,MEIS2,NEXMIF,NCAM2,NELL2,NFIX,NRCAM,PAX6,PCDH9,TMEM38A,PLXNB1,POU6F1,GDPD1,MDGA2,ELOVL2,EML5,GAL3ST4,RFX4,ATXN1,LRRTM4,LINC00461,KIF21A,NLGN1,MAST1,SOX2,SP4,NPAS3,LMO3,CLSTN2,SEMA4A,MCF2L,WSCD1,CUX2,PSD3,NR2E1,SLAIN1,FLRT1,FMN2,DPYSL5,LRP8,FZD3,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.17E-34 2.64E-30 2.14E-32 1.95E-31 142 311 "ASIC1,CSMD2,NDRG3,SLITRK1,ADCY8,SLC12A5,HFM1,SMIM17,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,NOL4,DOCK11,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,SYNPR,KIAA1549L,NRXN1,NRXN2,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,BRINP1,ZNF804A,SPOCK3,OLIG1,DPP6,SEZ6L2,RASA4,ELAVL3,ELAVL4,STARD3NL,EN2,OLIG2,DMTN,NSRP1,FABP7,TAOK3,FGF12,C1orf61,NSG2,NSG1,GABRA1,GABRG1,GABRG2,JPH4,GAP43,GART,DNER,FAXC,PCDH17,MAP7D2,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,NEGR1,HSF2,SHISA6,HSP90AA1,BRINP3,JAK1,KCND2,L1CAM,STMN1,VWA5A,NEXMIF,NCAM1,NELL1,NELL2,NNAT,NOVA1,KSR2,OPCML,PDGFRA,SERPINI1,NXPH1,LRRN3,MASP1,PLPPR1,STK32A,ZNF793,RALGDS,RIT2,RORB,RTN1,MAPK12,SCN2A,SCN3A,ASIC4,TRIM67,ZFP1,LIMCH1,SNAP25,MYT1L,SST,SYT1,SYT5,KIAA1107,RALYL,SPX,CSMD1,RUNDC3B,HSPBP1,TMEFF2,VSNL1,ZFP37,CELF4,REEP1,FSTL5,ANKS1B,PLPPR5,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000 FaceBase_RNAseq 5.72E-34 2.92E-30 2.35E-32 2.15E-31 312 984 "ABR,EMILIN3,ACTN2,NDRG2,ADCY2,ERMN,PLEKHH1,KIAA1211,PTCHD1,MTUS1,PCDH19,SRPX,ARHGAP20,LTBP4,GPRASP2,ANK3,FGD2,EPB41L5,APOC1,SHTN1,CDK10,ASCL1,NCOA1,RASL11B,ASTN1,ATP1A3,ATP2B1,KIF1A,ADGRB2,SNAI3-AS1,BCL7A,FGF17,PROM1,BMPR1B,C1QC,CACNA1G,LDLRAD4,CACNA1B,CACNA2D1,HAP1,VSTM2A,MAP7,INA,REPS2,LONRF2,CDH2,KCNAB3,CDH8,CDO1,CRLF1,ADGRG1,SRSF11,CHN2,SLIT2,LHX2,NRXN3,KIAA1549L,NRXN1,TJP2,NIPBL,ABI3BP,IGDCC3,CREB5,ANKRD44,ABCG1,CRYM,CSF1R,FEZ1,PLCH2,CTNND2,RIMS2,ST18,TOX,SCRN1,SPOCK2,BRINP1,JAKMIP2,RUSC2,CCDC3,DLG2,DMD,CDON,SHANK1,DTNA,MAMLD1,SEMA3D,EFNA3,EGFR,RASA4,ELAVL2,ELAVL3,ELAVL4,ELN,TMEM35A,EMX2,OLIG2,EPB41,EPB41L1,LRRC17,EPHA5,SLC43A2,APC2,RRAGB,ADGRV1,EYA1,F3,CLVS1,TUBB3,TUBB4A,CHST15,FCGRT,MED12L,OLFM1,FGF11,FGF12,FOXG1,DPYSL4,TRIM16,ATP2C1,FUT9,TPPP3,NRG3,FYB1,PHYHIPL,GAA,ILDR2,GAD1,GAD2,JPH4,ARPP21,TMEM8B,SRRM4,STARD10,KIAA1841,GCNT2,PCDH17,PPARGC1A,RUNDC3A,ZNF276,GLDC,GLRB,TOX3,PCDH11X,MAP7D2,KCNMB4,GNG3,GPM6A,GPM6B,CECR2,PCLO,STMN2,GRIK2,NR3C1,GSN,RNF165,MFSD2A,SOX21,PSIP1,FAM107A,FAM222A,CELF3,WIF1,TOX2,FRMD5,FRMD3,SYNPO,IGFBPL1,NEGR1,SHISAL1,HES5,IL11RA,BRINP3,INSM1,KCNK1,KIF5C,KIT,VWA5A,MAOB,MAP2,MBP,IL17D,SHC3,MEIS2,SRSF12,CD200,SAMD5,CCDC80,SCG3,TAGLN3,NEXMIF,MYT1,TCEAL5,NCAM2,NELL2,NFIA,NFIX,NNAT,NRCAM,PAK3,CNTN3,PAX6,PCDH9,PDE1A,GDAP1L1,SEMA5B,TMEM38A,PLCL1,SLC25A23,PLXNB1,NECAB2,NXPH1,POU6F1,MAPK10,PRODH,GDPD1,SLC22A23,APTX,MDGA2,ELOVL2,EML5,CEP97,ACSS3,SUSD4,FEZF2,RBBP8,ZMAT4,DUSP15,ZFHX4,MYH14,RAVER2,EMID1,LGR4,RTN1,STX1B,DGLUCY,SALL1,MAPK12,ATXN1,LRRTM4,LINC00461,HES6,HSPA4L,SCG5,KIF21A,SH3GL3,FERMT1,DOCK10,NTNG1,CCDC92,NLGN1,SLC1A2,SLC6A9,SMARCA4,MAST1,SNAP25,SOX2,SP4,BEX1,NPAS3,CLSTN2,KANK1,GSE1,FGD4,ZFR2,SYNE2,RHBDL3,ADAMTS17,PLCB1,SYP,MTCL1,SEMA4A,MCF2L,ADGRL3,WWC1,WSCD1,CUX2,WASHC4,PHF24,FAM189A1,PSD3,CCDC173,TEX15,HEY1,NR2E1,BEX4,TNNT1,TPD52,TRO,KCNE5,CA14,TST,CADM1,UCHL1,SLAIN1,FLRT1,TSPAN11,FMN2,NDRG4,DPYSL5,PMEPA1,CADM2,LRP8,STMN4,ADAMTS9,PCDH15,NAV3,NAV2,TMEM163,PCBP4,FZD3,FRMD6,SENP7" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_1000 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000 PCBC 7.00E-34 3.57E-30 2.86E-32 2.60E-31 315 998 "TTYH1,SYN3,FAM43B,CSMD2,TMEM132B,ADCYAP1R1,ADD2,UNC5A,OLMALINC,SYT13,DOC2A,ANK1,LRCH2,PPFIA2,CNIH2,VAT1L,PPP4R4,ZFYVE28,PLA2G4C,ALDH4A1,ATP1A2,ATP1A3,CADM3,DOCK11,CARMIL3,AZGP1,LDHD,CA8,CACNA1A,DIRAS1,SYT6,VSTM2A,CLDN10,LDB2,DCLK1,UBE2L6,CHGA,CHGB,CHRNA4,RAB3C,CHRNB2,RAB33A,NRXN1,NRXN2,TJP2,ABCG2,ARHGEF6,PCYT1B,CABP1,ANKRD35,IGDCC3,HS3ST5,CP,CRMP1,C1QL2,SNCAIP,LRRC3B,GALNT9,RIMS4,SLC45A1,FAM131B,SEC14L5,ECE2,HDAC9,KATNAL2,TOX,PHYHIP,BRINP1,JAKMIP2,TMEM130,PLPPR4,PARD6A,NTM,AK5,RABGAP1L,CHRDL1,HS3ST2,DOCK2,FAM57B,DPYSL2,ARRDC4,EDIL3,ST8SIA3,ATL1,CACNG7,EBI3,AASS,LINC00599,ELAVL2,TMEM35A,CALCRL,LRRC17,RASGRP2,SEZ6,EPHB1,ANKRD13B,NCALD,CDHR1,ETV1,PIPOX,CEND1,HSPA12B,FABP7,TUBB3,TUBB4A,PPP1R1B,ZNF589,OLFM1,ACTL6B,MAD2L2,HPCAL4,AGAP2,FLT1,SYT3,AKAP3,SORBS1,CGREF1,GPR153,ST6GALNAC3,CSPG5,NSG1,HHIPL1,TMEM151A,ABLIM2,JPH4,IQGAP2,GAP43,SRRM4,ACSS1,CPLX2,DNER,IGSF5,NEU3,ALDH1L1,C1QL1,RUNDC3A,TTBK1,GLDC,TOX3,LOXL3,GNAO1,GNG3,GNG4,LNX1,TDRKH,CCDC184,LPAR4,MCHR1,PCLO,RAPGEF4,GRIA4,GRM3,LINGO1,WIF1,IGSF21,C1orf94,FRMD5,HRH3,FRMD3,INSYN1,ARHGAP36,NEGR1,LRRC75A,ATCAY,BTBD17,SHISAL1,KNDC1,DISP2,IGSF1,SCIN,LRRTM3,OLFM3,KCND2,KCNMA1,KCNN2,KCNN3,KCNQ2,KHK,CREG2,KIF5A,CAMK2N2,FGFBP3,C2orf80,PIK3AP1,MAP2,MAPT,SCAMP5,PPM1L,WDR49,CPNE9,SESN3,STK32C,BLOC1S2,MT1M,SCG3,MX1,LAYN,FXYD7,NAP1L2,NAP1L3,NEFM,NELL2,ALDH1L2,NOS1,NOVA2,NPTX1,NPTX2,NTRK3,ZDHHC22,PAH,PAK3,PCSK1,PDE3A,TMOD2,GDAP1L1,NALCN,CAMKV,ST8SIA5,FXYD1,PLP1,PCDH18,SCHIP1,SEPT4,EPB41L4B,POU3F4,PPP2R2B,NKAIN4,PRKCB,KLK6,GDPD2,PTN,PTPRN,PTPRN2,PTPRO,PTPRZ1,TMEM145,PYGM,RASGRF2,SLC6A15,ZMAT4,RGS7,RIT2,RORB,BAALC,RIMKLA,STX1B,RYR1,DRAXIN,SCN4B,PPM1E,FERMT1,FHOD3,BCAN,NLGN1,LRRC55,IGSF9B,SNCB,SOX1,TRERF1,SOX2,SOX3,NMNAT2,LHFPL4,SPP1,UNC5B,LMO3,SMOC1,INKA2,STAC2,ACSBG1,ABCC8,RHBDL3,ARHGEF9,ARC,SYP,SYT1,SLC37A2,SYT4,CNTN2,ACSL6,TCF4,TMEM151B,SLC19A3,PCDHAC2,SLC35G2,RNF175,CHST8,SPX,FBXL16,ENHO,TIMP4,RELL2,TLL2,ANKRD24,RASD2,SYNPO2,TMEFF2,DNAJC12,MGAT5B,VAV1,VGF,VSNL1,TSPAN11,RBFOX3,LGI4,TRIM9,CRB2,DPYSL5,LAMP5,SLC30A3,SLC17A7,KCNAB1,TMEM163,TMEM63C,NETO1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_500 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.00E-34 4.08E-30 3.24E-32 2.95E-31 81 125 "CSMD3,ANK2,VAT1L,SLC7A14,CADPS,KIF1A,ADGRB3,NRP2,INA,LONRF2,DCLK1,CHGB,RAB3C,RAB33A,NRXN1,FAM171B,CRMP1,FEZ1,PLXNA4,NRSN1,SCRN1,SNAP91,SPOCK3,DLG2,EBF1,EDNRB,FRY,ELAVL2,ELAVL4,DENND4A,EYA1,FABP7,TUBB3,ATP8A1,FDFT1,FGF13,NSG2,TPPP3,GABRB3,GAP43,SYT17,IGSF5,GFRA1,GFRA2,GNAO1,STMN2,GRIA2,DISP2,LIX1,TUBB2B,KIF5A,KIF5C,L1CAM,SYTL4,SCG3,MYT1,NCAM1,NEFM,NELL2,NOVA1,TMOD2,PFKP,SERPINE2,MAPK10,EML5,ZMAT4,RET,RTN1,SCN2A,SCN3A,SCG5,SNAP25,SNRPN,SCN3B,SEPT3,SYT11,SYP,SYT1,CUX2,CADM1,STMN4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K1 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 8.92E-34 4.55E-30 3.58E-32 3.27E-31 118 233 "TTYH1,NCKAP5,GALNT16,RNF157,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,LRRC4C,NCOA1,ASTN1,ADAM23,ADGRB3,JAZF1,CACNA1A,VSTM2A,LONRF2,CDH8,EVI5L,SRSF11,FOXN3,SLIT2,NRXN3,KIAA1549L,NRXN1,IGLON5,ARHGEF6,CNTFR,WHRN,SLC4A8,SLC35F1,CREB5,AATK,CSF2RA,FEZ1,ERC2,ST18,HDAC9,TOX,SCRN1,DCC,RUSC2,SV2A,DMD,SHANK1,DTNA,MAMLD1,TMEM35A,ENO2,LRRC23,EPHA5,APC2,CHST15,SEMA6C,DPYSL4,NRG3,ACSS1,PPARGC1A,GPM6B,MFSD2A,NEGR1,BRINP3,KCNN3,MEIS2,ADAM22,NRBP2,TAGLN3,NEXMIF,NCAM2,NELL2,NFIA,NTRK2,GPR137C,PCDH9,NLGN3,SEMA5B,TMEM38A,FAT3,POU6F1,MAPK10,MDGA2,PTPRD,ENOX1,PRRT2,MEG3,STX1B,ATXN1,LRRTM4,NLGN1,SLC1A3,FAM214B,SMARCD3,NPAS3,CLSTN2,DIP2A,ZFR2,RHBDL3,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,ACSL6,CUX2,AZIN2,PSD3,THRA,KCNE5,SSBP2,FLRT1,TRIM9,FMN2,LYPD6,STMN4,WNK2,ST8SIA2,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.54E-33 1.30E-29 1.01E-31 9.22E-31 82 129 "UNC79,ANK2,PPFIA2,CADPS,BCHE,INA,RAB3C,NRXN1,FAM171B,ERC2,RIMS2,ST18,KIAA0408,HDAC9,JAKMIP2,ZNF804A,SNAP91,SPOCK3,SRGAP3,DLG2,RAB39B,EBF1,ST8SIA3,EDNRB,ELAVL2,ELAVL4,KCNMB2,DENND4A,EYA1,CLVS1,FABP7,FGF13,SGIP1,PHYHIPL,GABRB3,GAP43,SRRM4,GNAO1,TDRKH,GPR22,PCLO,GRIA2,GRIA4,HLF,LIX1,KCNA4,KIF5C,SYTL4,MAP2,SCG3,NAP1L2,NCAM2,NEFM,NEK1,NOVA1,PCDH9,TMOD2,PLP1,PPP2R2B,PKIA,STK32A,EML5,PTPRZ1,RADX,RGS7,NUDT11,RNASEL,SATB1,SCN3A,KIF21A,SNAP25,SNCA,SCN3B,EPB41L3,NUDT10,SYT1,SYT4,AGTPBP1,CUX2,CADM1,FSTL5,SCG2" Coexpression Atlas BM Top 100 - hypothalamus BM Top 100 - hypothalamus Body Map 4.74E-33 2.42E-29 1.87E-31 1.71E-30 59 74 "SLC12A5,ERMN,CARNS1,AQP4,CALB1,CALB2,INA,SYNGR3,SYNPR,CALY,ST18,RIMS3,OLIG1,ELAVL2,OLIG2,NSG2,PNMA2,GABRA1,GABRB1,GABRG2,GAD1,GAP43,GFAP,GNAS,CNDP1,GPR37,STMN2,ARHGAP36,OPALIN,CELF5,LIX1,KCNJ16,C2orf80,MAG,MAP4,MBP,MOBP,MOG,NEFM,NEFH,NKX2-2,SERPINI1,ANLN,TMEM235,PAQR6,SCN2A,SNRPN,SST,SYT1,TAC1,TF,SPX,SEZ6L,PRR18,SLAIN1,P2RY12,CELF4,SCG2,SLC17A6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.00E-33 3.06E-29 2.35E-31 2.15E-30 133 286 "ASIC1,CSMD2,SLITRK1,SLC12A5,SMIM17,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,PRC1,INA,SEPT7,LONRF2,CDH8,SYNPR,KIAA1549L,NRXN1,NRXN2,CNN3,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,BRINP1,ZNF804A,SPOCK3,OLIG1,DPP6,RASA4,ELAVL3,ELAVL4,EN2,OLIG2,DMTN,FABP7,TAOK3,RACK1,FGF12,C1orf61,SYNCRIP,PDLIM5,NSG2,NSG1,GABRA1,GABRG1,GABRG2,JPH4,GAP43,DNER,TOX3,MAP7D2,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,NEGR1,SHISA6,HSP90AA1,HES5,BRINP3,KCND2,STMN1,NEXMIF,NACA,NAP1L1,NCAM1,NELL1,NELL2,NNAT,NOVA1,KSR2,OPCML,PDGFRA,SERPINI1,NXPH1,LRRN3,PLPPR1,VEPH1,RIT2,RORB,RPS20,RTN1,SCN2A,SCN3A,ASIC4,SLITRK3,TRIM67,LIMCH1,SNAP25,MYT1L,SST,SYT1,SYT5,KIAA1107,TCF12,RALYL,CSMD1,RUNDC3B,TMEFF2,VSNL1,TSPAN11,MKRN3,CELF4,REEP1,FSTL5,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas BM Top 100 - ventral tegmental area BM Top 100 - ventral tegmental area Body Map 7.48E-33 3.82E-29 2.91E-31 2.66E-30 56 68 "SLC12A5,ERMN,CARNS1,SYT13,AQP4,VXN,INA,SYNGR3,SYNPR,CALY,ST18,CX3CR1,OLIG1,ELAVL2,OLIG2,C1orf61,NSG2,GABRA1,GABRG2,GAD1,GAP43,GFAP,CNDP1,GPR37,STMN2,OPALIN,LIX1,KCNJ16,MAG,MAP4,MBP,MOBP,MOG,NEFM,NEFH,ANLN,PMP2,TMEM235,QDPR,TMEM255A,RFX4,PAQR6,SCN2A,SLC1A2,SNAP25,SNRPN,SPP1,SYT1,TAC1,TF,SPX,PRR18,SLAIN1,P2RY12,SCG2,SLC17A6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.07E-32 5.47E-29 4.14E-31 3.77E-30 114 225 "DPF1,NCKAP5,ADCYAP1R1,PLEKHH1,KIAA1211,PCDH10,APBB1,EPB41L5,ASCL1,NUMB,ATP1A3,KIF1A,PROM1,DDR1,HAP1,CDH2,CDH8,JAM2,LHX2,NRXN3,NRXN2,QKI,SLC35F1,CSNK1E,CNTNAP2,CTNND2,RIMS2,ST18,JAKMIP2,ELMO1,SRGAP3,RAB39B,MAMLD1,EDNRB,PLXNC1,ELAVL2,ELAVL4,RTN3,FABP7,DPYSL4,FUT9,B3GAT1,PHYHIPL,GABRB3,IQGAP2,C15orf41,ACSS1,KIAA1841,PPARGC1A,GLDC,MAP7D2,GNG3,GPM6A,GPM6B,TDRKH,PCLO,MFSD2A,SOX21,USP51,INSM1,TUBB2B,KIF5C,LRRC4B,PAXBP1,LSAMP,MBP,PPM1L,SCG3,NELL2,NOVA1,GPR137C,PAK3,PCMT1,SEMA5B,PROX1,GDPD1,ELOVL2,EML5,PTPRZ1,ARID4A,RTN1,LINC00461,ZFP2,SOX6,CASC3,HSPA4L,KIF21A,PPM1E,ARX,SLC12A2,MAST1,SNAP25,SOX2,KIF1B,NPAS3,MPRIP,ACSBG1,SYT11,SYNE2,SYN1,MCF2L,ZEB1,ARHGEF12,NR2E1,TP53BP1,UCHL1,WNT7A,ZFP41,CELF4,REEP1,STOX2,RSPRY1,GAN,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 1.15E-32 5.86E-29 4.41E-31 4.01E-30 101 185 "TMCC3,SYT13,ANK3,VAT1L,TNRC6C,DACT3,KIF1A,GPC2,CALB1,RUNX1T1,SEPT7,DCLK1,CHGB,NRXN1,TMEM59L,CRMP1,PITPNM3,ARHGAP32,DNAJC6,CEP170,CPEB2,RCAN1,SEZ6L2,EFNB3,ELAVL2,ELAVL3,RCAN2,EPHA5,NCALD,OLFM1,NBEA,NSG2,NSG1,PNMA2,SARAF,DKK3,GABRG2,GAP43,PCDH17,GNAO1,GNG3,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,CELF3,NEGR1,CELF5,ATCAY,KIF5C,KLC1,LSAMP,GIT1,SCG3,HS6ST3,MYO5A,NCAM1,PAK3,PBX1,PCDH9,GNG2,TMOD2,MAGEL2,PPP2R2B,VSTM2L,PKIA,RALGDS,ZFHX4,RTN1,SCN2A,SCN3A,WDR47,NAPB,SNAP25,SNRPN,SCN3B,NMNAT2,PEG10,BEX1,EPB41L3,SEPT3,SYT1,SYT4,ANKRD12,KIAA0930,RBFOX2,TTC3,TUBB2A,UCHL1,VGF,ATP6V0E2,NDRG4,CELF4,REEP1,STMN4,TUBA1A,SCG2,RTN4,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.31E-32 6.70E-29 5.00E-31 4.56E-30 131 281 "ASIC1,CSMD2,SLITRK1,SLC12A5,SMIM17,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,NOL4,TTC9B,ADGRB1,ADGRB3,CDK5R1,CACNA1B,CACNA1E,CAMK2B,VSTM2A,HIP1R,RUNX1T1,INA,SEPT7,LONRF2,CDH8,CDH18,SYNPR,KIAA1549L,NRXN1,NRXN2,IGDCC3,CRMP1,NCAN,PDE4DIP,PHACTR3,PLXNA4,ERC2,ST18,CCDC144A,BRINP1,ZNF804A,SPOCK3,OLIG1,DPP6,EEF1D,RASA4,ELAVL3,ELAVL4,EN2,OLIG2,DMTN,FABP7,TAOK3,FDFT1,FGF12,C1orf61,NSG2,NSG1,GABRA1,GABRG1,GABRG2,JPH4,GAP43,SEPT9,DNER,MAP7D2,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,GRM5,FAM19A2,PTPN5,NEGR1,SHISA6,HSP90AA1,BRINP3,KCND2,STMN1,MEST,MSI1,NEXMIF,NAP1L1,NCAM1,NELL1,NELL2,NNAT,NPY,NOVA1,KSR2,OPCML,PDGFRA,SERPINI1,PKM,NXPH1,LRRN3,PLPPR1,RIT2,RORB,RPS20,RTN1,SCN2A,SCN3A,ASIC4,TRIM67,LIMCH1,SNAP25,MYT1L,SOX2,SST,SYT1,SYT5,KIAA1107,RALYL,ITGB3BP,CSMD1,RUNDC3B,TMEFF2,VSNL1,CELF4,REEP1,FSTL5,ANKS1B,CA10,STMN4,TUBA1A,SCG2,PAK5,SLC4A10" Coexpression Atlas PCBC_ratio_EB_from-mRNA_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-method_mRNA_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.73E-32 8.82E-29 6.48E-31 5.91E-30 137 302 "DPF1,GPRIN1,ADCYAP1R1,DISP3,SPARCL1,ANK2,CNIH2,APLP1,CADPS,ATP1A3,CADM3,MIR9-3HG,CDK5R1,CACNA2D1,CALB2,CABP7,THSD7A,BRSK2,CBLN1,INA,DCLK1,ARHGAP33,CRLF1,ADGRG1,CHGB,LHX2,NRXN2,NGEF,CNR1,CRMP1,KIAA0408,TOX,RASSF2,BRINP1,NYAP1,FAM57B,EBF1,ATL1,CELSR3,LINC00599,ELAVL2,ELAVL3,ELAVL4,RCAN2,EPHB1,APC2,TUBB3,OLFM1,ACTL6B,SEMA6C,DPYSL4,NSG2,GPR153,NSG1,TMEM151A,GABRB3,JPH4,GAP43,SRRM4,CPLX2,DNER,RUNDC3A,C1QL4,CELF3,UBE2QL1,ARHGAP19,IGFBPL1,ATCAY,HES5,SCRT2,INSM1,KIF5A,KIF5C,L1CAM,MAP2,MAPT,MMP17,SCG3,MYH6,MYT1,FXYD7,NCAM1,NEFM,NELL1,NHLH1,NPY,NOVA1,NOVA2,NPPA,ZDHHC22,GDAP1L1,POU3F2,MIR124-2,PTPRN,PTPRN2,PID1,KIAA0895L,RTN1,S100B,MIR124-2HG,DRAXIN,LINC00461,HES6,SMPD3,LRRC55,SLIT1,MAST1,SNAP25,SCN3B,KIF21B,NMNAT2,NFASC,LRRC4,SEPT3,RHBDL3,TAC3,ROBO3,CNTN2,CUX2,PCDHGA10,FBXL16,RGMB,TRH,FNDC5,TMEFF2,MGAT5B,NDRG4,CELF4,REEP1,TMEM198,SHD,STMN4,SCG2,TMEM163,SLC17A6,MVB12B,ST8SIA2" Coexpression Atlas PCBC_ratio_EB_from-OSKM-L_vs_EB_from-ESC_cfr-2X-p05 Embryoid Body Cells-reprogram_OSKM-L_vs_Embryoid Body Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.73E-32 8.82E-29 6.48E-31 5.91E-30 137 302 "DPF1,GPRIN1,ADCYAP1R1,DISP3,SPARCL1,ANK2,CNIH2,APLP1,CADPS,ATP1A3,CADM3,MIR9-3HG,CDK5R1,CACNA2D1,CALB2,CABP7,THSD7A,BRSK2,CBLN1,INA,DCLK1,ARHGAP33,CRLF1,ADGRG1,CHGB,LHX2,NRXN2,NGEF,CNR1,CRMP1,KIAA0408,TOX,RASSF2,BRINP1,NYAP1,FAM57B,EBF1,ATL1,CELSR3,LINC00599,ELAVL2,ELAVL3,ELAVL4,RCAN2,EPHB1,APC2,TUBB3,OLFM1,ACTL6B,SEMA6C,DPYSL4,NSG2,GPR153,NSG1,TMEM151A,GABRB3,JPH4,GAP43,SRRM4,CPLX2,DNER,RUNDC3A,C1QL4,CELF3,UBE2QL1,ARHGAP19,IGFBPL1,ATCAY,HES5,SCRT2,INSM1,KIF5A,KIF5C,L1CAM,MAP2,MAPT,MMP17,SCG3,MYH6,MYT1,FXYD7,NCAM1,NEFM,NELL1,NHLH1,NPY,NOVA1,NOVA2,NPPA,ZDHHC22,GDAP1L1,POU3F2,MIR124-2,PTPRN,PTPRN2,PID1,KIAA0895L,RTN1,S100B,MIR124-2HG,DRAXIN,LINC00461,HES6,SMPD3,LRRC55,SLIT1,MAST1,SNAP25,SCN3B,KIF21B,NMNAT2,NFASC,LRRC4,SEPT3,RHBDL3,TAC3,ROBO3,CNTN2,CUX2,PCDHGA10,FBXL16,RGMB,TRH,FNDC5,TMEFF2,MGAT5B,NDRG4,CELF4,REEP1,TMEM198,SHD,STMN4,SCG2,TMEM163,SLC17A6,MVB12B,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.82E-32 9.28E-29 6.77E-31 6.17E-30 126 265 "TTYH1,ABAT,NDRG2,ADCYAP1R1,SPARCL1,SEMA6A,PCDH10,CCDC146,LRRC4C,ASCL1,PCDHGB4,ATP1A2,KIF1A,SEC11C,CA12,CACNB2,SPAG9,CD81,SEPT7,CDO1,CDR1,ADGRG1,NRXN1,CLU,QKI,ARHGEF6,CREB5,SNCAIP,LRIG1,FEZ1,NCAN,CST3,CTNND2,RASSF2,DBI,LYPD1,KBTBD11,DPP6,DTNA,EDNRB,LRRC17,EPHB1,ERBB4,ADGRV1,FAM198B,FABP7,FGFR3,C1orf61,NBEA,PDLIM5,CSPG5,FUT9,PHYHIPL,MEGF10,ILDR2,GATM,GFAP,HEPN1,LUZP2,DCLK2,GPM6A,GPM6B,GRM3,FAM107A,HAS2,SCRG1,CFAP126,C2orf72,HES5,LIX1,LIFR,FGFBP3,MT3,SCG3,MTTP,FXYD6,NCAM1,NELL2,NFIA,NFIX,NTRK2,OPHN1,ENPP2,SERPINE2,SEMA5B,PLP1,PLXNB1,PMP2,PSAT1,SCHIP1,FAT3,LRRN3,NKAIN4,HYDIN,MASP1,GDPD2,PTCH1,ELOVL2,PTN,PTPRZ1,TMEM231,VEPH1,RFX4,KLHDC8A,WLS,SALL1,BCAN,SLC1A2,SLC1A3,WDR47,SLC15A2,LIMCH1,SOX2,NPAS3,SMOC1,SULF2,MLC1,WWC1,VWA3A,TCF4,ENHO,HEY1,SEZ6L,RFTN2,FAM181B,RGMA" Coexpression Atlas BM Top 100 - vestibular nuclei superior BM Top 100 - vestibular nuclei superior Body Map 3.34E-32 1.70E-28 1.23E-30 1.13E-29 56 69 "SLC12A5,ERMN,SMIM17,SYT13,AQP4,CALB2,INA,SYNGR3,ST18,CX3CR1,OLIG1,ELAVL2,ELAVL4,OLIG2,PNMA2,GABRG2,GAD1,GAP43,GFAP,GNAS,CNDP1,GPR37,STMN2,ARHGAP36,LIX1,KCNJ16,C2orf80,MAG,MAP2,MAP4,MBP,MOBP,MOG,NEFM,NEFH,ANLN,PMP2,TMEM235,TMEM255A,PAQR6,SCN2A,SNAP25,SNRPN,SPP1,SST,VAMP1,SYT1,TAC1,TF,SPX,UGT8,SLAIN1,P2RY12,FSTL5,SCG2,SLC17A6" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.15E-32 3.14E-28 2.26E-30 2.06E-29 305 976 "EMILIN3,ACTN2,NDRG2,ADCY2,SLITRK1,RNF157,ERMN,PTCHD1,KIAA1324,SRPX,ARHGAP20,LTBP4,GPRASP2,PPFIA2,EPB41L5,PHYHD1,SHTN1,CDK10,ASTN1,TMEM108,KIF1A,ADGRB2,NRP2,ZNF599,PROM1,C1QC,CACNA1G,LDLRAD4,CA4,CA12,CACNA2D1,HAP1,VSTM2A,MAP7,CBLN1,INA,REPS2,LONRF2,CDH2,KCNAB3,CDH8,CDO1,TBRG4,CRLF1,LHX2,NRXN3,CLCN3,KIAA1549L,NRXN1,NRXN2,CLU,ABI3BP,CREB5,CRMP1,ANKRD44,AATK,CSF1R,FEZ1,NCAN,CNTNAP2,FAM169A,SLITRK5,GREB1,RIMS2,HDAC9,TOX,SCRN1,SPOCK2,AIF1L,JAKMIP2,RUSC2,CCDC3,CHRDL1,DLG2,DMD,SHANK1,DTNA,MAMLD1,E2F5,ST8SIA3,HEYL,SEMA3D,EGFR,RASA4,ELAVL2,PLEKHA1,ELN,TMEM35A,EMX2,EPB41L1,LRRC17,SEZ6,EPHA5,EPHB1,EPS8,APC2,PIPOX,RRAGB,ADGRV1,REEP2,TUBB3,TUBB4A,CHST15,FCGRT,FGF11,FHL1,FOXG1,SEMA4D,SYT3,DPYSL4,TRIM16,FUT9,TPPP3,NRG3,FYB1,PHYHIPL,GABRB3,ILDR2,JPH4,ARPP21,SALL3,TMEM8B,SRRM4,PCDH17,PPARGC1A,ZNF276,GLDC,GLRB,TOX3,PCDH11X,MAP7D2,GNG3,GPD2,TDRKH,LPAR4,CECR2,STMN2,GRIK2,NR3C1,GSN,RNF165,MFSD2A,SOX21,FAM107A,CELF3,WIF1,TOX2,FRMD5,FRMD3,SYNPO,IGFBPL1,USP51,NEGR1,HSP90AA1,ATCAY,ZIC5,HES5,IL11RA,BRINP3,CDH20,KCNK1,CREG2,IPO5,KTN1,VWA5A,MAOB,AQP11,IL17D,MEIS2,SRSF12,MOBP,CD200,CCDC80,TAGLN3,MYCN,NEXMIF,TCEAL5,NAP1L1,NASP,NCAM2,NELL2,NFIA,NFIX,NNAT,NOVA1,NRCAM,IGSF11,PAK3,CNTN3,PAX6,PCDH9,PRTG,PDE1A,SEMA5B,SNX10,TMEM38A,PKM,PLCL1,FXYD1,NECAB2,MAGEL2,NXPH1,POLR2F,POU6F1,PRKAR1B,MAPK10,PRODH,GDPD2,MDGA2,ELOVL2,PTPN13,EML5,PTPRZ1,RAB3A,ACSS3,ZCWPW1,ENOX1,FEZF2,ZMAT4,FIGN,ZFHX4,MYH14,EMID1,RTN1,STX1B,DGLUCY,SALL1,MAPK12,ATXN1,LRRTM4,HSPA4L,SCG5,KIF21A,SH3GL3,ARX,FERMT1,ASAP3,DOCK10,NTNG1,CCDC92,NLGN1,SLC1A2,SLC6A9,SLC8A1,SMARCD3,SNRPN,SOX2,BEX1,NPAS3,LMO3,PBLD,CLSTN2,AJAP1,SYT11,FGD4,ZFR2,RHBDL3,ADAMTS17,PLCB1,ASTN2,MTCL1,SEMA4A,ROBO3,MCF2L,TMEM178B,UNC5D,ADGRL3,WWC1,WSCD1,ACSL6,CUX2,TCF7L2,WASHC4,PHF24,FAM189A1,PSD3,TMEM121,NR2E1,BEX4,PRMT8,KCNE5,CA14,CADM1,SLAIN1,FLRT1,TSPAN11,RBFOX3,ZIC2,ZIC3,FMN2,LYPD6,ZBTB16,DPYSL5,CA10,PMEPA1,CADM2,LRP8,SLC38A1,PCDH15,NAV3,TMEM163,FZD3,KLHDC1,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 6.38E-32 3.25E-28 2.32E-30 2.12E-29 104 197 "ASIC1,SLITRK1,HFM1,PCDH10,ANK3,PPFIA2,LRRC4C,ASCL1,PCDHGB4,ADGRB1,CDK5R1,CACNA1A,HIP1R,RUNX1T1,INA,SEPT7,REPS2,CDH8,NRXN1,NRXN2,NIPBL,CNTN1,CRMP1,PHACTR3,ERC2,CCDC144A,NTM,OLIG1,DPP6,ELAVL2,ELAVL3,ELAVL4,EN2,OLIG2,FABP7,TUBB3,TAOK3,C1orf61,SGIP1,NSG2,CSPG5,NSG1,ZMAT1,GAP43,DNER,PCDH17,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,TOX2,SCRG1,NEGR1,HSP90AA1,HES5,KCND2,L1CAM,STMN1,MEST,NEXMIF,BEX5,NCAM1,NELL2,NFIX,NNAT,NOVA1,KSR2,OPCML,PCDH9,PDGFRA,GPR85,TMOD2,GDAP1L1,SLC25A23,PMP2,NXPH1,LRRN3,MDGA2,PTN,VEPH1,REV3L,RORB,RTN1,S100B,SCN2A,SCN3A,BCAN,SNAP25,MYT1L,SOX10,NPAS3,SIN3B,TCF12,TMOD1,TSPAN11,CELF4,REEP1,ANKS1B,STMN4,SCG2,PAK5,SLC4A10" Coexpression Atlas PCBC_EB_fibroblast_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 1.10E-31 5.59E-28 3.97E-30 3.62E-29 308 992 "AXIN2,AGT,SPARCL1,PPFIA4,PPFIA2,GAS7,APOC2,LGR5,ASCL1,KIF1A,BMP7,CACNA1G,BSN,MYRF,BAIAP3,CDK5R2,CA4,CABP7,CAMK2A,BRSK2,CBLN1,INA,DGKI,CDH8,CDH10,LGI1,NOG,CHGA,CHGB,CHRNA4,NDST3,SLIT2,LHX2,NRXN1,NRXN2,TMEM59L,SULT4A1,IGLON5,CNR1,CNTFR,AKAP6,COL9A1,COL11A2,AKAP5,SLC4A8,GAL3ST1,IGDCC3,SNCAIP,TENM4,CSF3R,ATRNL1,PLCH2,GALNT9,NCAN,RIMS4,PHACTR3,CNTNAP2,CALY,CFAP61,CTNND2,ST18,PYGO1,RIMS3,BRINP1,DCC,DCT,PLPPR4,SNAP91,SPOCK3,SRGAP3,HS3ST4,CDON,DUSP9,EBF1,USH1C,EDIL3,SEZ6L2,EDN3,SGK2,HEYL,SEMA3D,EFNA2,EFNB3,PLXNC1,LINC00599,ELAVL2,ELAVL3,ELAVL4,APC2,ADGRV1,NRN1,FABP7,TMEM132C,ZIC4,ZMYND10,ACTL6B,HPCAL4,C1orf61,FOXF2,NSG2,DACH2,CSPG5,NSG1,DLL3,B3GAT1,TPPP3,TMEM151A,PHYHIPL,MEGF10,GABRA3,ILDR2,ARPP21,GAP43,SRRM4,CPLX2,DNER,CYP46A1,GFRA1,GFRA2,FREM1,PCDH17,CSDC2,C1QL1,GJB1,RUNDC3A,TOX3,PCSK1N,GNG3,GPM6A,CCDC184,CECR2,STMN2,TPPP,GRIA1,GRIA2,C1QL4,GRIA4,GRID1,GRIK1,GRIK3,GRIN1,GRIN2D,GRM8,GUCY1A1,TMEM179,CELF3,WIF1,UBE2QL1,NXPH2,SCRG1,IGFBPL1,CELF5,IRF8,BTBD17,C2orf72,IGF1,NKD1,HES5,LIX1,SCRT2,INSM1,ITIH2,KCNA2,CDH20,KCNA6,KCNC1,KCND2,KCND3,KCNJ3,KCNJ4,KCNK2,KCNK3,KCNMA1,KCNN1,KCNQ2,KIF5A,KIF5C,LRRC4B,CLEC18A,C1orf194,MAP6,MAPT,MATN2,LRP1B,SCG3,TAGLN3,MTTP,RSPO2,MYBPC1,MYH6,MYL3,MYT1,FXYD7,NCAM1,NEFM,NELL1,NELL2,NHLH1,NPY,NPPA,NTRK2,NTRK3,OLR1,PAH,KCNK10,PAX6,PCDH8,PDE1A,PDGFRA,PENK,GDAP1L1,SEMA5B,PLCL1,HMGCLL1,PNMA3,PDZRN4,PRRX1,MAGEL2,POU3F2,PPP2R2B,NKAIN4,SMIM10L2B,PRPH,RELN,PSD,LAMA1,PTH1R,PTPRD,PTPRN,PTPRO,TMEM145,TMEM255A,RFX4,RGS4,ROBO2,RPE65,HUNK,KCNIP1,RTN1,RXRG,LINC00461,TMEM200C,PPM1E,ST8SIA1,SLC1A6,SLC6A1,LRRC55,SLC8A2,SLC8A3,SLIT1,SLN,MAST1,SORCS3,DMRTC1,IGSF9B,RIMS1,SNAP25,CABCOCO1,FAIM2,MYO16,MYT1L,SOX3,KIF21B,SOX10,NMNAT2,ENKUR,SPP1,PEG10,CLSTN2,SST,SSTR2,MLC1,ZFR2,SYT4,SYT5,TAC1,TAC3,CNTN2,ADGRL3,CUX2,TMEM151B,TF,CRB1,ASXL3,RIMBP2,SEZ6L,RASD2,TRH,FNDC5,AMOT,FRRS1L,FLRT1,FAM181B,WNT7A,ZIC1,ZIC3,KCNT2,CRB2,MKRN3,DPYSL5,SHD,STMN4,XKR7,SCG2,GAL3ST3,SLC17A6,FAM181A,PRRT4" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500 FaceBase_RNAseq 1.67E-31 8.50E-28 5.99E-30 5.46E-29 188 495 "TTYH1,ERMN,PLEKHH1,EPB41L5,APOC1,SHTN1,ZFYVE28,TMEM108,ATP2B2,KIF1A,ADAM23,TTLL9,PROM1,DST,CA4,CA12,THSD7A,DIRAS1,HAP1,MAP7,CBLN1,INA,ARHGEF1,CDK11B,LRRFIP1,CCPG1,CBARP,LHX2,KIAA1549L,NRXN2,DNAJB5,C4orf33,SLC35F1,FAM171B,CLIP3,LRRC3B,SUSD5,NCAN,SLITRK5,CTNND2,RIMS2,KATNAL2,JAKMIP2,CHRDL1,RAB39B,DTNA,ST8SIA3,ELAVL2,ELAVL3,EMX2,OLIG2,SEZ6,EPHB1,NCALD,APC2,PIPOX,RRAGB,CEND1,ADGRV1,REEP2,TUBB3,TUBB4A,FGF11,FHL1,NOP56,SYT3,COQ5,NSG2,DLL3,FUT9,PHYHIPL,GABRB3,ILDR2,SALL3,HIGD1B,SRRM4,GATM,CSDC2,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,GPD2,CECR2,PCLO,STMN2,RFFL,GRIK2,GRIK5,RNF165,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,USP51,LRRC75A,HSP90AA1,SHISAL1,HES5,LRRTM1,CDH20,KLHL23,KCNK1,KTN1,MAOB,MAP2,PPM1L,CPNE9,CCDC80,ADAM22,MYCN,NOVA1,NRCAM,IGSF11,PAK3,PAX6,PRTG,SNX10,SLC25A23,PMP22,MAGEL2,NXPH1,POU3F4,NKAIN4,MASP1,RELN,GDPD2,ELOVL2,PTPRZ1,FEZF2,GAL3ST4,FIGN,RFX4,MYH14,FBXW7,STK32B,YJEFN3,CCDC112,SALL1,MAPK12,HSPA4L,SCG5,ZFP30,KIF21A,ARX,NTNG1,FHOD3,CCDC92,TET1,SNRPN,SOX2,SOX5,BEX1,LMO3,C11orf87,SEPT3,AJAP1,SYT11,FGD4,SYN1,MTCL1,ROBO3,WWC1,TCF4,TCF7L2,WASHC4,NR2E1,BEX4,PRMT8,STXBP4,TUB,SLAIN1,MGAT5B,RBFOX3,ZIC2,ZIC3,ZNF23,ZBTB16,DPYSL5,CA10,SHD,ADAMTS9,TMEM163,WNK3,FZD3,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.76E-31 8.95E-28 6.26E-30 5.70E-29 144 332 "TTYH1,ABAT,CSMD2,NDRG2,ADCYAP1R1,OSBPL6,SPARCL1,SEMA6A,PCDH10,CCDC146,LRRC4C,ASCL1,PCDHGB4,ATP1A2,ADGRB1,CA12,VXN,SPAG9,SEPT7,KCNAB3,CDO1,CDR1,ADGRG1,FOXN3,CLU,QKI,CREB5,SNCAIP,LRIG1,NCAN,CST3,SDC3,CTNND2,RASSF2,DBI,FBXL5,LYPD1,NTM,OLIG1,CASP8AP2,DPP6,DTNA,EDNRB,SUGP2,OLIG2,LRRC17,EPS8,ETV1,ADGRV1,NSRP1,FAM198B,FABP7,FGFR3,C1orf61,PDLIM5,CSPG5,PHYHIPL,ILDR2,SEPT9,DNER,GATM,PCDH17,HEPN1,LUZP2,DCLK2,PSRC1,GPM6A,GPM6B,GRIK2,GRM5,ADAMTS6,HAS2,SCRG1,CFAP126,C2orf72,HES5,LIX1,ITGAV,KCND2,LIFR,FGFBP3,C2orf80,MT3,SCG3,NCAM1,NFIA,NFIX,NTRK2,OMG,OPCML,PDGFRA,ENPP2,SERPINE2,PLP1,PLXNB1,PMP2,SCHIP1,FAT3,IRX1,LRRN3,NKAIN4,GRAMD1C,HYDIN,MASP1,PTCH1,PTN,PTPRZ1,TMEM231,ARID4A,VEPH1,RFX4,RIT2,KLHDC8A,WLS,RYR3,S100B,SALL1,SARS,SCN3A,BCAN,SLC1A2,SLC1A3,EPN2,SLC15A2,ZFP1,LIMCH1,SOX2,FNBP1,NPAS3,ATP10B,SMOC1,SULF2,MLC1,WWC1,VWA3A,TCF4,ZEB1,HEY1,CSMD1,SEZ6L,RGMA,PCDH15,MARCH8,DPF3" Coexpression Atlas PCBC_ratio_EB blastocyst_vs_EB bone marrow_cfr-2X-p05 EB blastocyst_vs_EB bone marrow-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.79E-31 1.42E-27 9.87E-30 8.99E-29 149 351 "TTYH1,ABAT,ADD2,AXIN2,SPARCL1,SEMA6A,CNIH2,APBA2,CACHD1,VAT1L,TMEFF1,RASL11B,ATP1A2,KIF1A,BCHE,BCL7A,BMP7,GPC2,BAIAP3,INA,LGI1,LARGE1,CDO1,ADGRG1,TMEM59L,CNTFR,COL9A1,COL9A2,TCEAL2,ZNF521,SLC35F1,CRMP1,CRYM,FEZ1,FAM131B,RIMS3,AIF1L,LYPD1,SACS,DPYSL2,EDN1,CACNG7,ELN,NCALD,NRN1,REEP2,FABP7,TMEM132C,TUBB3,TUBB4A,SPSB4,MEX3B,FOXF2,DPYSL4,KHDRBS3,PNMA2,TPPP3,ILDR2,DNER,GDF1,GFRA1,RND1,GLDC,GP1BB,GPM6A,GPM6B,CECR2,ARHGAP19,IGFBPL1,CFAP126,CPT1C,ATCAY,ZIC5,TUBB2B,ITGA7,C2CD4C,KCNQ2,KIF5C,KIT,L1CAM,STMN1,MSANTD3-TMEFF1,FGFBP3,CLEC18A,MAP2,KITLG,MN1,MSI1,MYCN,RCOR2,NEFM,NELL2,PRTG,SEMA5B,PCDH18,PRRX1,SDK2,POU3F2,FSD1,VSTM2L,LAMA1,PTPRZ1,NKAIN1,TMEM231,BEND5,RFX3,RFX4,TMEM206,BAALC,PLPPR3,WLS,SALL1,DRAXIN,HES6,SLC6A8,SLIT1,SOX2,TNIK,SOX11,DOK5,ZNF423,NACAD,SEPT3,SYT11,CNTN2,ADGRL3,WSCD1,TRIM2,PCDHGB7,TIAM1,CBX5,RGMB,CA14,RFTN2,TUBB2A,SLAIN1,FAM181B,TSPAN11,ZIC2,ZIC3,NDRG4,DPYSL5,DNALI1,LRP8,RGMA,TUBA1A,PANTR1,FZD3,VANGL2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 3.41E-31 1.74E-27 1.20E-29 1.09E-28 79 127 "ASIC1,KIDINS220,PPFIA2,THSD7A,RUNX1T1,INA,SEPT7,ADGRG1,ZNF521,NCAN,ST18,DCC,EBF1,KMT5B,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,EPB41,NRN1,TUBB3,NSG2,GABRB3,GAD1,GAD2,NKX6-2,GAP43,DNER,GNAO1,GPM6A,STMN2,GRIA2,C1QL4,GRIK2,NEGR1,CELF5,INSM1,KIF5C,MEIS2,CD200,SCG3,TAGLN3,NAP1L3,NCAM1,NEFM,NEUROD1,NHLH1,NNAT,PCDH9,PCSK1,GDAP1L1,SCHIP1,PLPPR1,ROBO2,RTN1,CSRNP3,SCN3A,SYBU,CXXC4,MYT1L,KIF21B,SEPT3,SYT1,SYT4,TAL1,CNTN2,ZEB1,TCF12,RBFOX2,RGMB,FNDC5,FAM155A,UCHL1,TSPAN11,NDRG4,CELF4,TMEM163,SENP7" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.96E-31 2.02E-27 1.38E-29 1.25E-28 114 232 "CCDC85A,RNF157,LTBP4,GPRASP2,PPFIA2,MAGEE2,NCOA1,ASTN1,ADAM23,ADGRB3,JAZF1,CACNA1A,VSTM2A,LONRF2,CDH8,EVI5L,FOXN3,SLIT2,LHX2,KIAA1549L,NRXN1,CLTB,IGLON5,ARHGEF6,IGDCC3,CREB5,AATK,CSF2RA,FEZ1,ERC2,HDAC9,TOX,SCRN1,RUSC2,DLX1,DMD,SHANK1,DTNA,MAMLD1,TMEM35A,EMX2,ENO2,EPHA5,APC2,ADGRV1,CHST15,DPYSL4,NRG3,ACSS1,PPARGC1A,GLDC,MAP7D2,GPM6B,GRIK2,MFSD2A,KLF12,NEGR1,BRINP3,KCNH2,KCNN3,CREG2,MEIS2,MSI1,ADAM22,MSR1,NRBP2,TAGLN3,NEXMIF,NCAM2,NELL2,NTRK2,PAX6,PCDH9,PDE1A,PGAM2,NLGN3,SEMA5B,TMEM38A,FAT3,POU6F1,MAPK10,MDGA2,ENOX1,PRRT2,MEG3,STX1B,ATXN1,LRRTM4,NTNG1,NLGN1,SLC1A3,SMARCD3,SOX11,NPAS3,CLSTN2,DIP2A,RHBDL3,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,CUX2,PSD3,THRA,ZIC3,FMN2,LYPD6,LRP8,STMN4,WNK2,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2 Gudmap RNAseq 3.96E-31 2.02E-27 1.38E-29 1.25E-28 355 1209 "TTYH1,SERPINA3,SYN3,ACLY,KDM5D,RNF157,AXIN2,SORCS1,GRAMD1B,SNX30,HECW2,PCDH19,NME5,SPARCL1,ALCAM,ARHGAP20,CDC42BPA,MYH7B,SMIM29,PPFIA2,CNIH2,PKP4,APBB2,GAS7,APLP1,UPRT,FAM131A,CACHD1,VAT1L,TNRC6C,KIAA1614,IGDCC4,ARRB2,CADPS,NCOA1,ASTN1,ZNF583,NOL4,ADAM15,ADGRB2,BCHE,JAZF1,CACNA1G,CACNA1A,CACNA2D1,CACNB2,BRSK2,RUNX1T1,ARHGEF25,LDB2,FMNL3,USP2,CDK11B,LONRF2,DCLK1,CCPG1,CRLF1,NUMBL,SOCS6,JAM2,EPS15L1,KIAA1549L,NRXN1,MYL6B,CNTFR,COL9A3,IFFO1,ZNF521,SLC35F1,FAM171B,ENTPD4,CREB5,HAPLN1,ANKRD44,NCOR2,GDA,CLIP3,SNCAIP,CSF1,TENM4,CSF2RA,LRIG1,FEZ1,ARHGEF10,VCAN,SOCS5,PLCXD3,CFAP61,CYBB,BOC,HDAC9,ARHGAP24,TOX,PHF19,IP6K1,BRINP1,GIT2,PITPNC1,DNAJC6,ELMO1,GSDME,SNAP91,SEC16A,DMD,DNM1,SHANK1,ATN1,FAM78B,EDN3,SEMA3D,TMTC1,CACNG7,EFNA2,EFNA3,FAM13A,SORBS3,CERCAM,ELAVL4,RGS17,ELN,EML1,PLEKHO1,VPS13B,ANKRD13B,EPS8,HSPA12B,WAC,FABP7,OLFM1,FGFR1,SCARA3,ZMYND15,SEMA6C,FOXO3,FLNC,SGIP1,AFF2,SYT3,COQ5,TMEM107,ZBED3,PDLIM5,USP21,TPK1,TMEM151A,NRG3,TVP23A,DKK3,GAA,GABRA1,BRPF3,GAP43,ACSS1,GATM,GFRA2,FREM1,PCDH17,CSDC2,GHR,HPGDS,GLI2,GLRB,KCNMB4,GNAO1,GNG3,GPM6A,FUT10,GPR19,GRIA4,GRIK1,LINGO1,ATOH8,IRAK3,HAS2,INSYN1,SYNPO,CFAP126,NEGR1,CPT1C,ICA1,IGF1,NKD1,BRINP3,TUBB2B,KCNA6,KHK,LAMA2,LRRC4B,VWA5A,MAP2,MAP4,MATN2,MEIS2,AFF1,MMP16,MN1,ADAM22,NRBP2,MYBPC1,LINC00672,MYO7A,MYO9A,NEXMIF,NBL1,NCAM1,NEFM,NELL1,NFIA,CNOT4,NPR2,DDR2,OGG1,ZNF827,PDE4D,GPR173,CDK14,PGAM2,NLGN3,SEMA5B,PKD1,ZFYVE21,FTO,PLP1,PCDH18,PMP22,PRRX1,SDK2,SLC36A4,FAT3,POU6F1,PPP1R1A,NKAIN4,PRKAR1B,EPDR1,MDGA2,CNTLN,PTH1R,PTPRD,PTPRE,PTPRG,PTPRZ1,RIPOR1,FAT4,BEND5,PRRT2,MORC4,SETD5,MYH14,ARMC5,ROBO1,ROBO2,ACER3,RIMKLA,TCP11L1,LRRK2,PLPPR3,MEG3,KCNIP3,ZNF354C,STX1B,SEMA6D,ATXN1,LRRTM4,PRCD,TNFRSF19,MRAS,SCG5,SH3GL3,FHOD3,CNKSR2,NLGN1,ST8SIA1,DZIP1,CLSTN1,ZNF365,SLC4A3,FAM81A,SLC6A9,ARHGEF40,SLC12A4,ELMO2,EFHD1,TET1,ZNF667,RIMS1,PALLD,PDZRN3,KDM4B,DOP1A,TRERF1,TNIK,GLT8D1,SPP1,IQSEC2,CLSTN2,COLGALT2,SAMSN1,EPB41L3,INKA2,STAC2,SULF2,ARHGEF9,ANKRD12,ADGRL3,TBCEL,IQCE,EHBP1,TCF4,SATB2,TCF7,TCF12,USP22,SZT2,AZIN2,PSD3,SIK3,CHST8,THRA,ASXL3,KAT6B,NPL,TPM2,TPM4,SYNPO2,TRPS1,RFTN2,TST,ZKSCAN5,SLAIN1,FLRT2,PLEKHH2,PLPPR2,LMF1,VSNL1,WIPF1,WNT7A,XRCC4,ZNF23,ZNF32,KCNT2,SLC26A10,ZNF184,EML6,ANKS1B,SLC30A4,LRP8,RGMA,TUBA1A,NAV3,PLD4,MVB12B,ADAMTS10,AAAS,PIANP,ST8SIA2" Coexpression Atlas PCBC_ratio_EB UCB CD34+Z_vs_EB blastocyst_cfr-2X-p05 EB UCB CD34+Z_vs_EB blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.98E-31 3.05E-27 2.06E-29 1.88E-28 75 117 "DPF1,DISP3,CNIH2,SHROOM2,ATP1A3,DOCK11,CDK5R1,SLC25A14,CBLN1,INA,DCLK1,CRLF1,ADGRG1,CLCN4,PCYT1B,CTNND2,KIAA0408,BRINP1,EBF1,ATL1,LINC00599,ELAVL2,ELAVL3,APC2,TUBB3,CHST15,OLFM1,FGF13,TMEM164,NSG2,GPR153,PHYHIPL,GAP43,CPLX2,DNER,RUNDC3A,GNG4,GPM6B,CELF3,UBE2QL1,ARHGAP19,IGFBPL1,TCEAL6,ATCAY,SCRT2,INSM1,MAP2,MID1,SCG3,RTL5,MYT1,NAP1L3,NCAM1,NHLH1,NOVA2,GDAP1L1,VSTM2L,PTPRN,RTN1,LINC00461,HES6,LRRC55,SLIT1,NMNAT2,NFASC,NACAD,SEPT3,ROBO3,CNTN2,PCDHGB6,RGMB,FNDC5,ZIC3,STMN4,SCG2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000 FaceBase_RNAseq 6.38E-31 3.25E-27 2.18E-29 1.99E-28 301 970 "TTYH1,EMILIN3,ACTN2,NDRG2,GALNT16,ADCY2,ADCY8,RNF157,PTCHD1,KIAA1324,C1QTNF1,SRPX,ARHGAP20,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,LRRC4C,CDK10,ZFYVE28,PDE8B,NCOA1,ASTN1,CADM3,ADAM23,CARMIL3,ADGRB2,ADGRB3,JAZF1,C1QC,CACNA1G,LDLRAD4,CA4,CACNA1A,CACNA2D1,VSTM2A,RUNX1T1,REPS2,LONRF2,KCNAB3,CDH8,EVI5L,CDO1,CRLF1,FOXN3,SLIT2,LHX2,KIAA1549L,NRXN1,CLTB,VAX2,IGLON5,ARHGEF6,IQCK,WHRN,COL9A2,SLC4A8,ABI3BP,IGDCC3,SLC35F1,CREB5,HAPLN1,ANKRD44,AATK,SNCAIP,CSF1,CSF1R,CSF2RA,FEZ1,LRRC3B,ERC2,HDAC9,MYADM,TOX,DGKB,SCRN1,SPOCK2,DCC,C8orf34,RUSC2,CCDC3,DLG2,DMD,DNM1,SHANK1,DRP2,DTNA,MAMLD1,ABCC9,SNX29,HEYL,SEMA3D,EFNA3,EGFR,RASA4,RGS17,ELN,TMEM35A,ENO2,EPB41L1,LRRC23,LRRC17,EPHA5,EPS8,APC2,CEND1,CHST15,FCGRT,FGF11,FGF12,SEMA6C,DPYSL4,TRIM16,DLL3,STAU2,TPPP3,NRG3,TVP23A,FYB1,ZMAT1,JPH4,ARPP21,TMEM8B,ACSS1,PCDH17,CSDC2,PPARGC1A,LYVE1,ZNF276,GLRB,PCDH11X,GNG4,GPM6B,CECR2,GRIK4,NR3C1,GSN,MFSD2A,FAM107A,GUCY1B1,WIF1,FRMD3,SYNPO,NEGR1,ZIC5,IL11RA,BRINP3,INPP1,CDH20,KCNK1,KCNN3,CREG2,VWA5A,GPR155,IL17D,MEIS1,MEIS2,SRSF12,CD200,CCDC80,ADAM22,MSR1,NRBP2,TAGLN3,RSPO2,NEXMIF,TCEAL5,FXYD7,NCAM1,NCAM2,NELL1,NELL2,NFIA,NFIX,NNAT,NPR2,NRGN,NTRK2,GPR137C,ZNF827,CNTN3,PCDH9,PRTG,PDE1A,PDE4D,NLGN3,SERPINE2,SEMA5B,TMEM38A,PLCL1,SMOX,FXYD1,TRHDE,PRRX1,SDK2,EPB41L4B,FAT3,NXPH1,POU6F1,IRX1,CCDC144B,NKAIN4,PRKAR1B,MAPK10,PRODH,MDGA2,CNTLN,PTPRD,RAB3A,ACSS3,IQSEC3,RAP1GAP,ZCWPW1,ENOX1,ZNF493,BEND5,ZMAT4,PRRT2,PRIMA1,ZFHX4,MYH14,MRAP2,BAALC,STK32B,EMID1,LRRK2,MEG3,STX1B,DGLUCY,SALL1,ATXN1,LRRTM4,MRAS,SH3GL2,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A3,FAM214B,SLC6A9,SLC8A1,MAST1,SMARCD3,PDZRN3,SOX10,NPAS3,CLSTN2,DIP2A,ZFR2,RHBDL3,ADAMTS17,PLCB1,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,UNC5D,ADGRL3,TBX15,SATB2,CUX2,PHF24,TMEM151B,FAM189A1,PSD3,THRA,NR2E1,PIK3R5,SYNPO2,TRPS1,KCNE5,SSBP2,TUB,FLRT1,TSPAN11,ZIC1,ZIC2,ZNF32,TRIM9,FMN2,NDRG4,LYPD6,CELF4,PMEPA1,CADM2,LRP8,STMN4,PCDH15,NAV3,TMEM163,WNK2,KLHDC1,DPF3,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.85E-30 1.45E-26 9.67E-29 8.82E-28 147 350 "TTYH1,SLC25A25,SLITRK1,PCDH10,FGD2,LCORL,APBB1,ALS2,SHTN1,ASCL1,PTCH2,ATP2B2,MPDZ,BCL7A,CFAP410,DDR1,DIRAS1,HAP1,ARHGAP33,ADGRG1,SRSF11,NRXN3,CRMP1,CSNK1E,NCAN,CNTNAP2,SLITRK5,ST18,USP6NL,RASSF2,SCRN1,DCC,ELMO1,SRGAP3,NTM,KBTBD11,DLX1,DTNA,AASDH,EDNRB,FSD1L,ELAVL3,OLIG2,EPHB1,APC2,ADGRV1,CLVS1,FABP7,ZIC4,TUBB3,SUCO,FOXG1,AFF2,DPYSL4,ATP6V1H,NSG2,DLL3,FYN,GAD1,AHCYL1,BRPF3,IQGAP2,SRRM4,ACSS1,RUNDC3A,DCLK2,GPM6A,GPM6B,STMN2,GRIK2,GRIK3,RNF165,MFSD2A,FAM222A,CELF3,TOX2,FRMD5,IGFBPL1,CELF5,ATCAY,HES5,KCNH2,LRRC4B,PAXBP1,ARHGAP12,MAP2,MARK1,MDM4,SHC3,MEST,TAGLN3,MYT1,NNAT,NRCAM,TMOD2,GDAP1L1,SPATA6,MAPK10,PROX1,GDPD1,GAL3ST4,DPF2,ARHGEF10L,EXD2,RTN1,LINC00461,ASRGL1,HSPA4L,SCG5,FBXO11,FAM81A,CXXC4,MAST1,SNAP25,LMBRD1,SOX2,SOX11,LHFPL4,KIF1B,ZBTB43,NPAS3,STAU1,GSE1,SYT11,SYP,TACC1,MCF2L,TMEM178B,ACSL6,CUX2,CLASP1,FRYL,BHLHB9,TP53BP1,TUB,UCHL1,MGAT5B,ZIC1,ZIC3,DPYSL5,STMN4,STOX2,SNX27,WNK2,FZD3,SNX14,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 3.16E-30 1.61E-26 1.07E-28 9.71E-28 125 273 "TMCC3,KIDINS220,SYT13,ANK3,VAT1L,TNRC6C,APP,DACT3,KIF1A,GPC2,CALB1,RUNX1T1,LDB2,INA,SEPT7,DCLK1,CHGB,NRXN1,TMEM59L,PREPL,CRMP1,PITPNM3,ARHGAP32,DNAJC6,CEP170,CPEB2,RCAN1,SEZ6L2,EFNB3,EIF4G2,ELAVL2,ELAVL3,RCAN2,EPHA5,NCALD,ABCA8,OLFM1,ATP5PD,NBEA,NSG2,NSG1,PNMA2,B3GAT1,SARAF,DKK3,GABRG2,GAP43,PCDH17,GNAO1,GNAS,GNG3,GNG4,GPM6A,CCDC184,PCLO,STMN2,GRIA2,KIF3A,CELF3,NEGR1,CELF5,ATCAY,TUBB2B,KCNJ4,KIF5C,KLC1,STMN1,LSAMP,GIT1,SCG3,HS6ST3,MYO5A,BEX5,FXYD6,NCAM1,PAK3,PBX1,PCDH9,PDE4D,GNG2,TMOD2,MAGEL2,PPP2R2B,VSTM2L,PKIA,RALGDS,ZFHX4,RTN1,SCN2A,SCN3A,SCG5,FBXO11,WDR47,CCDC88A,NAPB,SNAP25,SNRPN,SCN3B,NMNAT2,PEG10,BEX1,EPB41L3,SEPT3,NECAB1,SYT1,SYT4,ANKRD12,KIAA0930,RBFOX2,TTC3,TUBB2A,UCHL1,VGF,TRIM9,ATP6V0E2,NDRG4,CELF4,REEP1,MEIS3,SLC38A1,STMN4,TUBA1A,SCG2,RTN4,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 8.51E-30 4.34E-26 2.86E-28 2.60E-27 97 184 "KIDINS220,ZNF608,ANK2,ANK3,APLP1,GPC2,CALB1,THSD7A,KALRN,INA,AKAP6,MAGED1,CRMP1,CNTNAP2,CTNND2,TCAF1,RIMS3,SCRN1,DCC,DCTN1,FAM57B,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,ENO2,EPB41,NCALD,NRN1,TUBB3,IP6K2,GPR153,NSG1,DLL3,GAP43,SRRM4,DNER,GNG3,STMN2,CELF3,IGFBPL1,ATCAY,INSM1,KIF5C,KLC1,L1CAM,MAP4,MAP6,MEIS2,CD200,SCG3,TAGLN3,MDGA1,NCAM1,NEFM,NHLH1,NNAT,PAK3,PCMT1,PDPK1,GNG2,GDAP1L1,PKM,NECAB2,POU3F2,MAPK8,RALGDS,ZFHX4,ROBO1,ROBO2,RTN1,SCN3A,KIF21B,SOX11,NMNAT2,BEX1,NFASC,CLASP2,GSE1,SYT1,SYT4,TAC1,CNTN2,ZEB1,FRYL,RBFOX2,FNDC5,UCHL1,ZIC1,ZIC2,NDRG4,TCEAL7,STMN4,SCG2,PCBP4,SLC17A6" Coexpression Atlas BM Top 100 - accumbens BM Top 100 - accumbens Body Map 1.33E-29 6.80E-26 4.45E-28 4.05E-27 58 78 "SLC12A5,ADORA2A,CPNE5,ATP2B1,CACNA1E,CALB1,CDR1,SYNPR,LHX2,NGEF,CNR1,SLC32A1,DGKB,PLPPR4,ST8SIA3,PPP1R1B,FOXG1,NSG2,GABRA2,GABRA4,GABRA5,GABRB1,GABRG2,GAD1,GAD2,ARPP21,CYP46A1,GNAL,PTPN5,WIF1,HPCA,CELF5,SOWAHA,KCNJ4,KCNQ2,C2orf80,NPY,NRGN,GPR88,PCDH8,PDYN,PENK,PPP3CA,PRKCB,MEG3,SCN2A,ELMOD1,SLC1A2,SLC8A1,DDN,SST,NCDN,TAC1,FBXL16,RASD2,LAMP5,KCNAB1,MPPE1" Coexpression Atlas PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05 MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.40E-29 7.12E-26 4.62E-28 4.21E-27 361 1257 "RALGAPA1,DGCR6,EMILIN3,FMNL2,PLEKHG5,SORCS1,NLGN4X,ZNF608,CASKIN1,HACE1,OSBPL1A,NME5,SORCS2,WDR35,TXNDC16,CC2D2A,SPARCL1,SEMA6A,ALCAM,GPRASP2,AMT,ANK2,EP400,USP28,PPFIA4,APBA2,TMEFF1,ASCL1,STK33,CCDC74A,BRINP2,ASTN1,ALDH4A1,ATM,RNF182,BBS2,SEC11C,BCHE,BMP7,WASF1,BAIAP3,CFAP410,CA8,CACNA2D1,ARHGEF25,CDC25B,ARHGAP33,LGI1,CACNA2D2,CIART,RCBTB2,SYNPR,LHX2,CCDC151,CNTFR,CNTN1,WHRN,SLC25A27,COL9A1,COL9A2,COL9A3,TCEAL2,RTTN,ZNF521,IGDCC3,CP,ZNF385A,CPS1,FAM171B,SEC31B,PREPL,AKAP12,CRYBB1,CLIP3,CRYM,TENM4,FAM169A,SLITRK5,GREB1,ARHGEF4,GPSM1,BOC,TOX,KIF26A,TBC1D5,SPOCK2,AIF1L,DCT,MYEF2,SV2A,SRGAP3,ARNT2,MED12,NR1D2,CDON,DPH1,DTNB,E2F5,SEMA3D,EFNA2,EFNA3,FAM13A,RASA4,AASS,ASB3,C3orf18,EML1,HSD17B14,LRRC23,SRRM1,ERCC2,NCALD,EFS,ECSIT,EZH1,REEP2,ARMCX1,CLVS1,CHST15,KAT8,ZNF589,GTF2IRD2,FGF11,SPSB4,DPYSL4,NBEA,USP21,ST6GALNAC3,CSPG5,MSANTD4,TPPP3,AP4B1,DOT1L,ZNF512,PHYHIPL,DKK3,MEGF10,ILDR2,FAM184B,TMEM8B,C15orf41,WASF3,TUBGCP4,GDF1,GPR162,GFRA1,TCERG1,GLI2,STARD3,ZNF638,KDM2B,KCNMB4,LOXL3,GPM6A,GPM6B,DIPK1C,B4GALNT4,STON1,MCHR1,GPR37,CECR2,CNTRL,GRB10,CROCCP2,C1QL4,PARD3B,GRIK5,LINC01089,PSIP1,GYG1,FAM222A,MUM1,ATG4C,HAS2,ZHX1,HMX1,CFAP126,CPT1C,ZIC5,RBPJ,LIX1,CDH20,KCNJ4,KCNK1,KIT,KPNA5,TTYH2,PAXBP1,MSANTD3-TMEFF1,LMO1,FGFBP3,SMAD9,NAT8L,CLEC18A,MARK1,LDLRAD3,LRP1B,MEIS1,MEIS2,PPM1L,MN1,MPP2,MSI1,NRBP2,MXI1,MYCN,RTL5,FXYD6,NDP,RCOR2,NEK1,NELL2,NEUROD1,NRCAM,NUMA1,OPCML,CNTN3,PAX6,PBX1,CDK18,PRTG,PFKFB4,DUSP26,PIK3R1,PKD1,XRN1,PKM,FAM216A,PCDH18,ANKRD16,SDK2,ING3,FAT3,NKAIN4,RASGEF1B,SLC26A11,VPS13C,PTCH1,MTMR10,PTH1R,ZIK1,PTPN13,PTPRD,TMEM145,PEX2,PYGM,TMEM231,RAD52,RALGDS,OXR1,FEZF2,BEND5,RBBP6,FIGN,RGS12,KIF7,SLC25A36,ZNF532,PNMA8A,RORB,FBXW7,PRR5L,EMID1,LGR4,PLPPR3,SOX8,HSD11B1L,KCNIP1,DGLUCY,SALL1,HSPA4L,PUF60,SCG5,ASAP3,MAGI3,DZIP1,CLSTN1,SLC4A3,BTBD3,PKNOX2,SLC6A8,CDK5RAP3,CCDC88A,ZNF334,RCOR3,LIMCH1,SNCA,KIF13A,KDM4B,SOX2,TSNAXIP1,KDM3A,IZUMO4,KDM4C,ZNF423,COLGALT2,ZC4H2,ARHGEF26-AS1,ADHFE1,GSE1,SYT11,NUDT10,C12orf76,KAZN,DDHD2,MCF2L,ADGRL3,AGTPBP1,TCF4,DMXL2,CUX2,TCF12,PCDHGB6,RALYL,PCDHB10,PCDHB9,OBSL1,CRTC1,AHCYL2,HIF3A,CRB1,LEFTY2,TIAM1,NR2E1,KAT6B,CDK20,TRH,TRPC1,FNDC5,CA14,TSC2,SSBP2,TUB,RPRM,FRRS1L,DNAJC12,FLRT1,CCDC136,CCDC14,LMF1,LGI4,ZIC2,ZIC3,ELFN1,ZNF45,CRB2,TCEAL7,ZBTB38,ZBTB16,ZNF177,ZNF184,INTS3,MAP3K12,SHD,TMEM178A,WNK2,HRASLS,FAM13C,FZD3,PIANP,IFT88" Coexpression Atlas BM Top 100 - corpus callosum BM Top 100 - corpus callosum Body Map 1.67E-29 8.50E-26 5.49E-28 5.00E-27 53 67 "ERMN,PLEKHH1,CARNS1,AQP4,ASPA,SYNJ2,MYRF,VXN,SLC5A11,CDR1,LHX2,MAP4K4,ST18,SPOCK3,OLIG1,OLIG2,FGF1,FOXG1,FOLH1,LINC00320,GALNT15,GFAP,CNDP1,GPR37,GRM3,OPALIN,LIX1,TTYH2,MAG,MBP,MOBP,MOG,NKX2-2,ENPP2,ANLN,FA2H,TMEM235,KLK6,GLDN,PAQR6,AMER2,SPP1,NKAIN2,CNTN2,TF,SPX,SLC44A1,PRR18,UGT8,SLAIN1,P2RY12,CLDND1,ANKS1B" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.78E-29 9.09E-26 5.83E-28 5.31E-27 80 135 "SLITRK1,ADCYAP1R1,DPP10,ANK2,VAT1L,SLC7A14,ASCL1,ATP2B2,ADGRB3,ARHGEF7,CACNA1B,BRSK2,CDC42,LGI1,CHGB,CNR1,CNTN1,AKAP6,MYRIP,CRMP1,PHACTR3,NRSN1,ST18,SCRN1,ZNF804A,TMEM130,SNAP91,EBF1,ATL1,ELAVL2,ELAVL4,CLVS1,FABP7,TUBB3,GABRB3,GAP43,SYT17,CPLX1,GFRA2,GPR22,STMN2,FAM19A2,INSM1,KCNQ2,KIF5A,KIF5C,SYTL4,MAP4,MAPT,SCG3,NCAM2,NEFM,NTRK2,PIRT,SLC10A4,GNG2,DUSP26,NALCN,PIK3R1,PLP1,MAPK10,PRPH,PTPRO,RET,RGS4,RTN1,S100B,SNAP25,UNC80,SCN3B,C11orf87,SYT11,SYN2,SYT1,SYT4,CUX2,TUB,TMEFF2,FSTL5,STMN4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.86E-29 9.50E-26 6.05E-28 5.52E-27 256 791 "C3orf14,METAP1D,ADCY2,KLHL13,PCDH19,OSBPL1A,SORCS2,C1QTNF3,SPARCL1,ARHGAP20,SYT13,LRCH2,ANK2,APAF1,VAT1L,TNRC6C,IGDCC4,CASK,CADPS,ZSCAN18,ASTN1,DPY19L3,DOCK11,ADGRB2,IL33,CACNA2D1,RUNX1T1,ARHGEF25,LDB2,CCNH,USP2,AP4M1,REPS2,CDH2,CDH10,DCLK1,RCBTB2,FOXN3,CHGB,SOCS6,BTF3L4,ABI3BP,ZNF521,FAM171B,AKAP12,HAPLN1,RNF14,NCOR1,CLIP3,LRIG1,SOCS5,PLCXD3,GPSM1,BOC,RASSF2,DNAL1,HEPH,HP1BP3,CEP170,RHOBTB1,SRGAP3,NTM,DYNC1I1,EBF1,EDIL3,EDNRA,ATL1,SEMA3D,TMTC1,EFNA3,EFNB3,EGFR,PLXNC1,ELAVL2,CALCRL,EPHA5,EFS,ADGRV1,ARMCX1,EFEMP1,ATP8A1,FGF11,CAMSAP1,SUCO,UBE2E3,MEX3B,CAP2,DPYSL4,NBEA,TMEM107,ZBED3,NSG2,DACH2,TPPP3,GAA,GAB1,CHL1,NEK6,GFRA2,GGTA1P,GHR,LYVE1,BRD8,GLI2,GLRB,RAB40B,GPT2,GPM6B,LPAR4,GRIA1,GRIA4,GRIK1,GRM3,PSIP1,RASSF8,HAS2,UBE2QL1,ATXN2L,KLF12,NEGR1,CPT1C,IGF1,NKD1,RBPJ,KCND2,VWA5A,SMAD1,MAOB,MAP2,MATN2,MDFI,MEIS1,MEIS2,SCAMP5,MMP16,MN1,SESN3,ADAM22,NRBP2,MTR,MYH3,FXYD7,NAP1L2,FXYD6,NAP1L3,NDP,NEFM,NEK1,NFIA,NFIX,NNAT,NOVA1,NTRK2,DDR2,CLDN11,ZNF827,PBX1,PCDH8,PCSK5,PDE1A,PDGFRA,GPR173,GPR85,PIK3R1,FTO,PCDH18,PLTP,PRRX1,ING3,TNPO2,MED1,CEP41,PKIA,CNTLN,PTCH1,PTPRD,TUG1,TMEM255A,RALGDS,FAT4,RBBP6,TSPY26P,RNASEL,ZFHX4,LGI2,TMLHE,MEG3,ZNF354C,CCDC112,SATB1,CSRNP3,LRRTM4,FAM19A1,FNIP1,SCAF8,FAM102A,NTNG1,FNDC3A,ST8SIA1,DZIP1,SLC4A3,MTERF2,SLN,MAPKBP1,KIF13A,PDZRN3,ZCCHC24,ZNF423,TROVE2,CLSTN2,EPB41L3,ZC4H2,LRRC4,MAPK8IP3,SULF2,STXBP1,SYT1,ANKRD12,ADGRL3,KLHL4,ANO4,EHBP1,VWC2,TCF4,TCF7L2,PCDHB7,PCDHB3,PUM2,HIF3A,TEX15,ZFPM2,ITGB3BP,HHIP,ASXL3,KAT6B,TNNT1,TPM1,TPM2,TRIO,SSBP2,TUBB2A,CADM1,VSNL1,LYPD6,PMEPA1,RGMA,PARP6,STOX2,WNK3,FAM13C,RTN4,CERS6,ZNF248,SSPN,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.47E-29 1.26E-25 7.96E-28 7.25E-27 144 345 "TTYH1,ABAT,NDRG2,ADCYAP1R1,ERMN,SPARCL1,SEMA6A,PCDH10,CCDC146,LRRC4C,IGDCC4,ARHGAP5,ASCL1,PCDHGB4,CCDC181,ATP1A2,RNF182,BMP7,CA12,SPAG9,SEPT7,LGI1,CDO1,CDR1,ADGRG1,CHN2,JAM2,KIAA1549L,CLU,QKI,CNGA3,IGDCC3,CREB5,NCOR2,SNCAIP,TENM4,LRIG1,NCAN,CST3,CTNND2,TOX,RASSF2,DBI,LYPD1,DPP6,RCAN1,DTNA,EDNRB,FSD1L,EFNB3,LRRC17,ERBB4,ADGRV1,FAM198B,FABP7,FGFR3,C1orf61,PDLIM5,CSPG5,PHYHIPL,ILDR2,GATM,HEPN1,DCLK2,GPM6A,GPM6B,STON1,HAS2,FRMD3,SCRG1,CFAP126,C2orf72,IGSF1,HES5,LIX1,LRRTM3,LIFR,FGFBP3,MAP6,LDLRAD3,MSI1,NRBP2,MT3,RSPO2,MXI1,NCAM1,NFIA,NFIX,NPTX2,NTRK2,PRTG,ENPP2,CDK14,SERPINE2,PLP1,PLXNB1,PMP2,FAT3,NXPH1,LRRN3,NKAIN4,HYDIN,MASP1,PTCH1,PTN,PTPRO,PTPRZ1,PEX2,TMEM231,VEPH1,RFX4,ZFHX4,KLHDC8A,WLS,CLIP1,SALL1,ASRGL1,PUF60,BCAN,SLC1A2,SLC1A3,SLC15A2,LIMCH1,SOX2,SOX5,NPAS3,ITPRID2,SMOC1,SULF2,MLC1,WWC1,VWA3A,TCF4,TCF12,PSD3,CCDC173,HEY1,SEZ6L,PPIL6,FLRT2,TSPAN11,LRP8,RGMA,RTN4" Coexpression Atlas PCBC_EB_blastocyst_1000 Progenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 3.60E-29 1.84E-25 1.16E-27 1.05E-26 302 995 "SERPINA3,AXIN2,PCDH19,AGT,KCTD16,SORCS2,SPARCL1,PDZD4,DPP10,PPFIA4,APOC2,LRRC4C,LGR5,ASCL1,DACT3,RASL11B,KIF1A,BMP7,CACNA1G,MYRF,CA4,CAMK2A,BRSK2,CBLN1,CDH8,CDH10,CDH18,LGI1,NOG,CHGA,SYNPR,CHRNA4,LHX2,FAM19A5,IGLON5,CNR1,CNTFR,COL9A1,COL9A2,COL11A2,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HAPLN1,SNCAIP,TENM4,CSF3R,LRRC3B,ATRNL1,NCAN,RIMS4,PHACTR3,CNTNAP2,CTNND2,RIMS3,BRINP1,DCC,DCT,ZNF804A,LYPD1,PLPPR4,SNAP91,SPOCK3,DLX1,OLIG1,DNAH9,FAM57B,DPP6,DRP2,DUSP9,USH1C,EDN3,SYT15,SEMA3D,EFNA2,EFNB3,LINC00599,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,ADGRV1,NRN1,CLVS1,FABP7,TMEM132C,ZIC4,ZMYND10,SPSB4,ACTL6B,HPCAL4,C1orf61,FOXF2,ATP13A4,NSG2,DACH2,CSPG5,B3GAT1,TPPP3,TMEM151A,PHYHIPL,MEGF10,GABRA2,CHL1,ILDR2,NKX6-2,SALL3,GAP43,SRRM4,CPLX2,DNER,GFRA1,GFRA2,FREM1,GJB1,PCSK1N,GNG3,GPM6A,CCDC184,STMN2,GRIA1,GRIA2,C1QL4,GRIA4,GRIK1,GRM8,PTPRT,GUCY1A1,TMEM179,CELF3,WIF1,UBE2QL1,NXPH2,SCRG1,HPSE2,HMX1,IGFBPL1,HP,SHISA6,CELF5,BTBD17,C2orf72,IGF1,NKD1,KIAA1755,HES5,LIX1,SCRT2,BRINP3,INSM1,ITIH2,CDH20,KCNQ2,KIF5C,LRRC4B,PACRG,CLEC18A,C1orf194,MAP6,MAPT,LRP1B,SCG3,TAGLN3,MTTP,RSPO2,MYH6,MYL3,MYT1,NCAM1,NEFM,NELL1,NELL2,NHLH1,NNAT,NPY,NPPA,NTRK2,NTRK3,OLR1,PAH,KCNK10,PAX6,PCDH8,PRTG,PDGFRA,PENK,GDAP1L1,SEMA5B,HMGCLL1,PDZRN4,PRRX1,SDK2,NECAB2,MAGEL2,POU3F2,POU3F4,PPP2R2B,NKAIN4,PRPH,RELN,PSD,LAMA1,PTH1R,ELOVL2,PTPRD,PTPRO,TMEM145,NKAIN1,TMEM255A,FEZF2,KHDRBS2,CRTAC1,RFX4,RGS4,ZFHX4,LGI2,ROBO2,HUNK,KCNIP1,RTN1,RXRG,AMER2,LRFN5,LINC00461,TNFRSF19,TMEM200C,SOX6,SH3GL3,ST8SIA1,SLC1A3,SLC1A6,SLC2A5,PKNOX2,LRRC55,SLC8A3,TRIM67,TMEM132D,EFHD1,SLIT1,SLN,CXXC4,SORCS3,DMRTC1,RIMS1,SNAP25,CABCOCO1,SOX1,SOX3,SOX5,SOX10,SOX11,ENKUR,SPP1,LMO3,CLSTN2,SST,SSTR2,APOM,SEPT3,ZFR2,SYT4,SYT5,TAC1,TAC3,CNTN2,VWA3A,PCDHGB6,TMEM151B,SLC19A3,RNF175,TF,ENHO,ASXL3,NR2E1,RIMBP2,CSMD1,FNDC5,AMOT,FLRT1,FAM181B,WNT7A,ZIC1,ZIC3,KCNT2,CFAP52,CRB2,MKRN3,REEP1,DPYSL5,SHD,STMN4,SCG2,GAL3ST3,SLC17A6,DNAH10,SLC39A12,CBLN2,FAM181A,PRRT4,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k4 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.19E-29 2.13E-25 1.33E-27 1.22E-26 133 307 "ADCY8,SORCS1,RNF150,FAM135A,DPP10,PPFIA2,CADPS,ASPH,ASTN1,RNF182,NOL4,BACH1,LDLRAD4,CDH2,CDH10,DCLK1,RCBTB2,CHN2,SYNPR,NRXN3,COL9A1,BTF3L4,COL9A3,FAM171B,CREM,HAPLN1,CRYM,FEZ1,SOCS5,RIMS2,DOCK4,BRINP1,JAKMIP2,CEP170,GSDME,GRIN3A,RAB39B,DRP2,GOLT1B,EBF1,EDIL3,ST8SIA3,EDN3,EDNRB,ATL1,EGFR,ABI2,ASB3,KCNMB2,ETV1,WAC,ST3GAL6,SPSB4,FGF13,UBE2E3,MEX3B,SGIP1,PNMA2,TVP23A,MEGF11,GABRA1,SRRM4,GART,WASF3,GFRA1,PCDH17,PCDH11X,KIAA1958,RAB40B,B4GALNT4,RAPGEF4,GRIK1,GRM3,GRM7,KIF3A,GUCY1A1,GUCY1B1,MAP4K5,GYG1,RASSF8,HAS2,UBE2QL1,NEGR1,AGFG1,SHISA6,INSM1,KCNK2,MARK1,RSPO2,NAP1L2,NAP1L3,NDP,NPTX1,CLDN11,ZNF827,CNTN3,PDE1A,GPR85,SERPINI1,TRHDE,MAGEL2,LRRN3,PKIA,FAT4,ENOX1,SLC6A15,ZMAT4,LRFN5,SCN3A,FAM19A1,NTNG1,DZIP1,WDR37,NAPB,CXXC4,PDZRN3,NPAS3,C11orf87,ZC4H2,MPRIP,ELOVL4,CEP68,TTBK2,PLCB1,MTCL1,ACSL6,PCDHB7,HHIP,CADM1,RPRM,MKRN3,LRP8,GOPC" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 4.86E-29 2.48E-25 1.54E-27 1.40E-26 83 145 "SLITRK1,PTCHD1,KIAA1324,EPB41L5,PHYHD1,SHTN1,KIF1A,PROM1,HAP1,CDH2,LHX2,NRXN3,NRXN2,CRMP1,NCAN,CNTNAP2,SLITRK5,RIMS2,JAKMIP2,DTNA,ELAVL2,EMX2,EPHB1,ADGRV1,TUBB3,FHL1,FOXG1,FUT9,PHYHIPL,GABRB3,ILDR2,SRRM4,GLDC,TOX3,MAP7D2,GNG3,TDRKH,STMN2,GRIK2,RNF165,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,USP51,ATCAY,ZIC5,HES5,KTN1,NASP,NFIX,NOVA1,NRCAM,PAK3,PAX6,MAPK10,ELOVL2,EML5,PTPRZ1,FEZF2,RTN1,LRRTM4,HSPA4L,SCG5,KIF21A,ARX,SOX2,LMO3,SYT11,FGD4,TMEM178B,ACSL6,TCF7L2,NR2E1,PRMT8,SLAIN1,RBFOX3,ZIC3,DPYSL5,FZD3,SPATA13,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.88E-29 2.49E-25 1.54E-27 1.40E-26 141 336 "TTYH1,ABAT,NDRG2,ADCY2,ADCYAP1R1,SORCS1,SPARCL1,SEMA6A,ALCAM,CEP126,PCDH10,CCDC146,LRRC4C,ARHGAP5,ASCL1,PDE8B,PCDHGB4,ATP1A2,CADM3,MPDZ,BCHE,PROM1,DST,CA12,THSD7A,SPAG9,MAP7,SEPT7,CDO1,CDR1,ADGRG1,JAM2,CLU,TPP1,TMEM59L,QKI,NECTIN3,CREB5,SNCAIP,LRIG1,NCAN,CST3,CTNND2,RASSF2,DBI,LYPD1,DPP6,DTNA,EDNRB,EFNB3,LRRC17,ADGRV1,F5,FAM198B,FABP7,EFEMP1,ZMYND10,FGFR3,C1orf61,IQCG,FLNC,PDLIM5,CSPG5,TPPP3,PHYHIPL,DKK3,ILDR2,GATM,HEPN1,DCLK2,GPM6A,GPM6B,HAS2,SCRG1,CFAP126,C2orf72,HES5,LIX1,IL6ST,KCNN3,LIFR,FGFBP3,PACRG,MAN2A2,NRBP2,MT3,NCAM1,NELL1,NFIA,NFIX,NTRK2,ENPP2,SERPINE2,PLP1,PLTP,PLXNB1,PMP2,FAT3,LRRN3,NKAIN4,HYDIN,MASP1,PTCH1,PLPPR1,PTN,PTPRZ1,TMEM231,VEPH1,RDX,RFX4,KLHDC8A,NEK11,WLS,SALL1,ATXN1,BCAN,CLSTN1,SLC1A2,SLC1A3,SIRT2,SLC15A2,LIMCH1,SOX2,TNIK,ENKUR,NPAS3,SMOC1,SULF2,SEPT3,MLC1,TACR1,WWC1,VWA3A,TCF4,OBSL1,HEY1,SEZ6L,CFAP52,TRIM9,RGMA,FZD3" Coexpression Atlas BM Top 100 - substantia nigra BM Top 100 - substantia nigra Body Map 1.01E-28 5.16E-25 3.16E-27 2.88E-26 51 64 "SLC12A5,ERMN,PLEKHH1,CARNS1,AQP4,VXN,SYNGR3,CDR1,MAP4K4,ST18,CX3CR1,OLIG1,ELAVL2,OLIG2,C1orf61,GAP43,GFAP,CNDP1,GPR37,STMN2,OPALIN,LIX1,KCNJ16,MAG,MAP4,MBP,MOBP,MOG,MYBPC1,NEFM,NEFH,NKX2-2,ANLN,PMP2,TMEM235,QDPR,TMEM255A,PAQR6,SLC1A2,SPP1,SYT1,TF,SPX,SLC44A1,PRR18,UGT8,SLAIN1,P2RY12,CLDND1,ETNPPL,SLC17A6" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.76E-28 8.98E-25 5.44E-27 4.96E-26 156 395 "TTYH1,PLEKHH1,TAOK1,EPB41L5,SHTN1,ATM,ATP2B2,KIF1A,MPDZ,PROM1,CFAP410,DIRAS1,HAP1,KRIT1,CDH2,ZNF445,CFL2,LHX2,NRXN3,KIAA1549L,NRXN2,NMT2,DNAJB5,NECTIN3,SLC35F1,FAM171B,CRMP1,NCOR2,NCAN,SLITRK5,CTNND2,RIMS2,USP6NL,KATNAL2,JAKMIP2,ZEB2,ELMO1,SMG7,G3BP2,RAB39B,DTNA,ABI2,PLXNC1,EIF4G2,ELAVL2,ELAVL3,EMX2,OLIG2,EPHB1,APC2,EXTL2,ADGRV1,REEP2,ACSL4,ZIC4,TUBB3,SPSB4,FHL1,FOXM1,ATP6V1H,ATP2C1,NSG2,DLL3,FUT9,PHYHIPL,GABRB3,ILDR2,SRRM4,KIAA1841,GATM,PPARGC1A,BRD8,GLDC,TOX3,MAP7D2,GNG3,PCLO,TUBA1C,STMN2,GRIK2,RNF165,SOX21,CELF3,TOX2,FRMD5,DDX19B,IGFBPL1,USP51,ZIC5,HES5,LRRTM1,KTN1,L1CAM,MAP2,PPM1L,AFDN,MSI1,ADAM22,NOVA1,NRCAM,PAK3,PAX6,SLC25A23,PROX1,SLC22A23,ELOVL2,EML5,PTPRZ1,FEZF2,GAL3ST4,RFX3,RFX4,FBXW7,CCDC112,CASC3,TRA2B,HSPA4L,SCG5,KIF21A,ARX,FHOD3,SON,SOX2,SOX5,SP2,SPTAN1,LMO3,SEPT3,SYT11,FGD4,SYN1,TACC1,WWC1,WSCD1,TCF7L2,ZNF106,BHLHB9,NR2E1,PRMT8,TUB,SLAIN1,MGAT5B,MEAF6,RBFOX3,NSD2,ZIC3,ZNF24,REEP1,DPYSL5,STOX2,WNK3,FZD3,RTN4,SNX14,SOCS4,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 200 GSE76381_iPSMoleculeCountsPMLog2 1.76E-28 8.98E-25 5.44E-27 4.96E-26 156 395 "TMCC3,KIDINS220,SEMA6A,SYT13,ANK3,VAT1L,TNRC6C,APP,PDE8B,DACT3,KIF1A,GPC2,CALB1,RUNX1T1,LDB2,INA,SEPT7,DCLK1,CHGB,NRXN1,TMEM59L,QKI,CNN3,PREPL,CRMP1,NCOR1,PITPNM3,ARHGAP32,EARS2,DNAJC6,CEP170,LYPD1,CPEB2,RCAN1,AASDH,SEZ6L2,EFNB3,EIF4G2,ELAVL2,ELAVL3,RCAN2,EPHA5,NCALD,ABCA8,FABP7,OLFM1,ATP5PD,JKAMP,NBEA,NSG2,NSG1,PNMA2,B3GAT1,SARAF,DKK3,GABRG2,DENND2A,GAP43,PCDH17,GLUL,OS9,GNAO1,GNAS,GNG3,GNG4,GPM6A,GPM6B,CCDC184,PCLO,STMN2,GRIA2,KIF3A,CELF3,SCRG1,NEGR1,CELF5,ATCAY,TUBB2B,KCNJ4,KCNQ2,KIF5C,KLC1,STMN1,LSAMP,GIT1,CCDC80,SCG3,HS6ST3,MYO5A,BEX5,FXYD6,NCAM1,NFIA,PAK3,PBX1,PCDH9,PDE3A,PDE4D,GNG2,TMOD2,MAGEL2,NXPH1,PPP2R2B,VSTM2L,PKIA,PTN,PTPRZ1,RALGDS,ZFHX4,RTN1,SCN2A,SCN3A,SCG5,MAGI3,FBXO11,PPP4R3A,WDR47,CCDC88A,NAPB,LIMCH1,SNAP25,SNRPN,SCN3B,NMNAT2,PEG10,BEX1,EPB41L3,SEPT3,NECAB1,SYT1,SYT4,ANKRD12,MTCL1,ANO4,KIAA0930,FAM200B,TIAM1,RBFOX2,TTC3,TUBB2A,UCHL1,PLEKHH2,VGF,ZNF28,TRIM9,ATP6V0E2,NDRG4,CELF4,REEP1,MEIS3,SLC38A1,STMN4,TUBA1A,SCG2,RTN4,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_200_Genes GSE76381_iPSMoleculeCountsPMLog2 2.11E-28 1.08E-24 6.49E-27 5.91E-26 141 340 "TMCC3,SEMA6A,SYT13,ANK3,VAT1L,TNRC6C,PDE8B,DACT3,KIF1A,GPC2,CALB1,RUNX1T1,LDB2,SEPT7,DCLK1,CHGB,NRXN1,TMEM59L,QKI,CNN3,CRMP1,NCOR1,PITPNM3,ARHGAP32,EARS2,DNAJC6,CEP170,LYPD1,CPEB2,RCAN1,AASDH,SEZ6L2,EFNB3,ELAVL2,ELAVL3,RCAN2,EPHA5,NCALD,ABCA8,FABP7,OLFM1,JKAMP,NBEA,NSG2,NSG1,PNMA2,B3GAT1,SARAF,DKK3,GABRG2,DENND2A,GAP43,PCDH17,GLUL,OS9,GNAO1,GNG3,GNG4,GPM6A,GPM6B,CCDC184,PCLO,STMN2,GRIA2,CELF3,SCRG1,NEGR1,CELF5,ATCAY,KCNJ4,KCNQ2,KIF5C,KLC1,LSAMP,GIT1,CCDC80,SCG3,HS6ST3,MYO5A,NCAM1,NFIA,PAK3,PBX1,PCDH9,PDE3A,PDE4D,GNG2,TMOD2,MAGEL2,NXPH1,PPP2R2B,VSTM2L,PKIA,PTN,PTPRZ1,RALGDS,ZFHX4,RTN1,SCN2A,SCN3A,MAGI3,PPP4R3A,WDR47,NAPB,LIMCH1,SNAP25,SNRPN,SCN3B,NMNAT2,PEG10,BEX1,EPB41L3,SEPT3,NECAB1,SYT1,SYT4,ANKRD12,MTCL1,ANO4,KIAA0930,FAM200B,TIAM1,RBFOX2,TTC3,TUBB2A,UCHL1,PLEKHH2,VGF,ZNF28,TRIM9,ATP6V0E2,NDRG4,CELF4,REEP1,MEIS3,SLC38A1,STMN4,TUBA1A,SCG2,RTN4,CBLN2" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_cfr-2X-p05 Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.95E-28 1.51E-24 9.01E-27 8.21E-26 409 1501 "CPNE2,TTYH1,ABR,ABHD6,GALNT16,ADCY6,AXIN2,GRAMD1B,ZNF608,PLA2G6,ALAD,ALCAM,BCAR3,LTBP4,GPRASP2,OGT,ANK2,C6orf89,LCORL,APAF1,APBA2,APBB1,EPB41L5,APLP1,DGKD,FAM131A,VAT1L,CDK10,TMEM263,IGDCC4,ZSCAN18,ZBTB10,ASTN1,ATP1A2,STX16,ATP2B1,CADM3,ATP6V1G2,LINC00847,BBS2,BCL7A,DCAF5,BMP7,MTMR3,AP1M1,SGCE,NIPA1,GPC2,CFAP410,CAMK2D,TRIM41,CAST,HIP1R,SPAG9,ARHGEF2,CDH2,CDH8,LGI1,CCPG1,ADGRG1,RCBTB2,CBARP,RAB28,PPT2,CLCN3,CLU,CNN3,CNTFR,COL4A5,SLC25A27,COL9A2,MAGED1,ZNF521,CPS1,FAM171B,SEC31B,PREPL,ENTPD4,SH2B1,HAPLN1,CRY2,CLIP3,CST3,PNPLA8,GREB1,ARHGEF4,CTNND2,PPP6R2,GPSM1,BOC,TCAF1,ZFYVE16,SCRN1,ZEB2,HEPH,B3GAT3,HP1BP3,RUSC2,TMEM130,LYPD1,SGSM2,DLG4,DMD,DMPK,CD99L2,CDON,ARRDC4,E2F6,EDN1,KLHL5,SIDT2,EFNA2,EFNB3,MBNL2,RASA4,SORBS3,PLEKHA1,ING4,EMX2,HSD17B14,SLC43A2,NCALD,EFS,TMEM74,RRAGB,EZH1,EFEMP1,SLC9B2,SPSB4,FGFR3,BAIAP2,AMOTL2,PRKAG2,SUCO,SCARA3,MEX3B,CAP2,IP6K2,SEMA6C,EVL,FLNC,TMEM175,USP21,TRIM16,GPR153,TPPP3,DOT1L,BRSK1,GAA,ILDR2,FAM184B,DENND2A,FAM120B,GALC,NEK6,TMEM8B,WASF3,KIAA1841,GDF1,GPR162,AHDC1,GGT7,TOX3,MSL3,MRPS31P5,KIAA1958,PRRC2B,ATF7,STON1,LPAR4,CROCCP2,CACFD1,LINC01089,PTPN5,COQ10A,RABL2A,SOX21,GUCY1B1,RASSF8,MAN1B1,GABARAPL2,HMGCL,CFAP126,CPT1C,HSD17B1,HSF2,MSL1,LINC00667,IFI16,C5orf24,HES5,LIX1,IL6ST,TMEM240,IL11RA,ZNF385B,ITGA7,C2CD4C,ITPKB,OLFM3,LRRC4B,LIG4,LSAMP,CLEC18A,MAN2A2,MAP2,MBD1,ADAM11,MDFI,MEIS2,SRSF12,MEST,KCTD6,MGAT3,MOV10,SESN3,CCDC80,MSI1,BCO1,NRBP2,SAMD14,MXI1,MYO6,TCEAL5,FXYD6,NELL2,NPR2,NUCB2,NUMA1,ODF2,KCNK10,PALM,PAX6,PCDHGC3,PRTG,ENPP2,GPR173,PGAM2,PKD1,PLXNB1,C11orf49,LRP12,SCHIP1,SDK2,SPATA6,POU3F2,DRAM2,PPP3CC,NKAIN4,VSTM2L,SLC26A11,GDPD1,BCAS3,LAMA1,PTPN13,PTPRD,CASTOR1,RIPOR1,RAB5B,RALGDS,ROGDI,FEZF2,TRIM68,PRRT2,FIGN,RGS12,ZFHX4,TMLHE,PNMA8A,KIRREL1,BAALC,KIAA0895L,EMID1,CNTNAP3,MELTF-AS1,PLPPR3,PAQR6,HSD11B1L,ATAT1,WLS,YJEFN3,CLIP1,MAPK12,MIR124-2HG,SATB1,SBF1,ATXN7,SEC14L1,GALNT10,ASRGL1,COPZ1,SCG5,ARX,FNDC3A,FHOD3,R3HDM2,NLGN1,ST3GAL3,ANKRD6,PAAF1,CLSTN1,NBPF1,FAM214B,PKNOX2,SLC6A8,SIRT2,CDK5RAP3,SLC12A4,SCMH1,MTERF2,ELMO2,EFHD1,GKAP1,SMARCC2,TTC17,ANKRD36,SNCA,PALLD,FAM219A,DOP1A,WDTC1,SOX1,SPATA7,SOX11,ZSWIM8,TSPYL2,COLGALT2,STOX1,SMOC1,LRRC4,ST5,MAPK8IP3,SEPT8,RGL1,DIP2A,SULF2,SYT11,VAMP1,C12orf76,DDHD2,MCF2L,ADGRL3,DMXL2,ZFP90,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA3,PCDHB15,PCDHB10,PCDHB9,PCDHB4,CRTC1,AHCYL2,FAM200B,DICER1-AS1,GPR161,ZMAT3,TGFBR3,THBS4,TIAM1,RGMB,TRH,TRO,FNDC5,SSBP2,TTC3,CADM1,UBE2H,CCDC136,MICAL1,TSPAN11,NPDC1,ELFN1,ATP6V0E2,EMX2OS,CRB2,ZBTB16,ZNF154,AMZ1,DPYSL5,SH3GLB2,MEIS3,DNALI1,RGMA,GDPD5,ADAMTS9,SEMA3B,PPP1R3F,CAB39L,TRIM16L,PCBP4,MVB12B,PARP11,FZD3,DOCK8,KAT6A,FAM219B,RNF170,TTC7A,SNX14,PIANP,FRMD6,NETO2,RNF146,ST8SIA2,SENP7" Coexpression Atlas BM Top 100 - nodose nucleus BM Top 100 - nodose nucleus Body Map 3.05E-28 1.56E-24 9.27E-27 8.45E-26 52 67 "ERMN,PLEKHH1,CARNS1,BCAS1,SYNJ2,MYRF,CAPN3,VXN,SLC5A11,MAP4K4,CMTM5,ST18,CX3CR1,RASSF2,SPOCK3,OLIG1,OLIG2,GFAP,CNDP1,GPR37,GRM3,HAPLN2,TTYH2,MAG,MBP,MOBP,MOG,NKX2-2,CDK18,ENPP2,ANLN,PMP2,FA2H,TMEM235,KLK6,QDPR,TMEM206,GLDN,PAQR6,S100B,AMER2,SPP1,NKAIN2,CNTN2,TF,SLC44A1,PRR18,UGT8,SLAIN1,P2RY12,CLDND1,ANKS1B" Coexpression Atlas BM Top 100 - medulla BM Top 100 - medulla Body Map 3.95E-28 2.01E-24 1.19E-26 1.09E-25 51 65 "SLC12A5,ERMN,PLEKHH1,CARNS1,AQP4,TMEFF1,SYNJ2,CALB1,CALB2,VXN,DCLK1,MAP4K4,CNTN1,ST18,OLIG1,OLIG2,GALNT15,GFAP,CNDP1,GPR37,STMN2,LIX1,KCNJ16,MAG,MAP4,MBP,MOBP,MOG,NEFM,NEFH,NKX2-2,ANLN,PMP2,TMEM235,TMEM255A,RFX4,PAQR6,S100B,SCN2A,SNRPN,SPP1,SST,NKAIN2,SYT1,TF,SLC44A1,UGT8,SLAIN1,P2RY12,CLDND1,SLC17A6" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500 Gudmap RNAseq 4.40E-28 2.24E-24 1.32E-26 1.20E-25 447 1686 "TTYH1,SERPINA3,SYN3,ACHE,ACLY,EMILIN3,KDM5D,NDRG2,ADCY2,RNF157,AXIN2,SORCS1,GRAMD1B,SNX30,HECW2,PCDH19,NME5,C1QTNF1,SPARCL1,ALCAM,SRPX,ARHGAP20,CDC42BPA,MYH7B,SMIM29,PPFIA2,CNIH2,PKP4,APBB2,GAS7,APLP1,UPRT,FAM131A,CACHD1,VAT1L,TNRC6C,KIAA1614,IGDCC4,ARRB2,CADPS,PDE8B,NCOA1,ASTN1,ZNF583,NOL4,MYOM1,ADAM15,ADGRB2,BCHE,JAZF1,C1QC,CACNA1G,CACNA1A,CACNA2D1,CACNB2,BRSK2,RUNX1T1,ARHGEF25,LDB2,FMNL3,USP2,CDK11B,LONRF2,DCLK1,CDO1,CCPG1,CRLF1,NUMBL,SOCS6,JAM2,EPS15L1,KIAA1549L,NRXN1,MYL6B,ARHGEF6,CNTFR,COL9A3,ABI3BP,IFFO1,ZNF521,CP,SLC35F1,FAM171B,ENTPD4,CREB5,HAPLN1,ANKRD44,NCOR2,GDA,CLIP3,SNCAIP,CSF1,TENM4,CSF2RA,LRIG1,FEZ1,LRRC3B,ARHGEF10,VCAN,SOCS5,PLCXD3,CFAP61,CYBB,BOC,HDAC9,ARHGAP24,TOX,PHF19,KIF26A,DGKB,IP6K1,BRINP1,GIT2,PITPNC1,DNAJC6,ZNF804A,ELMO1,GSDME,SNAP91,CCDC3,SEC16A,DMD,DNM1,SHANK1,ATN1,FAM78B,EDN3,EDNRA,SEMA3D,TMTC1,CACNG7,EFNA2,EFNA3,FAM13A,SORBS3,CERCAM,ELAVL4,RGS17,ELN,EML1,CALCRL,PLEKHO1,VPS13B,LRRC17,EPHB1,ANKRD13B,EPS8,TLR7,RASL12,HSPA12B,WAC,FABP7,ST3GAL6,CHST15,FCGRT,OLFM1,FGFR1,SCARA3,ZMYND15,SEMA6C,FOXO3,FLNC,FLT1,SGIP1,AFF2,SYT3,COQ5,TMEM107,ZBED3,PDLIM5,USP21,TPK1,TPPP3,TMEM151A,NRG3,TVP23A,DKK3,GAA,GABRA1,BRPF3,B4GALNT1,GAP43,HIGD1B,ACSS1,GATM,GFRA2,FREM1,PCDH17,CSDC2,GHR,LYVE1,HPGDS,GLI2,GLRB,KCNMB4,LOXL3,GNAO1,GNG3,GPM6A,FUT10,GPR19,STON1,GRIA4,GRIK1,NR3C1,GRM7,GSN,LINGO1,GUCY1A1,GUCY1B1,ATOH8,IRAK3,HAS2,INSYN1,SYNPO,CFAP126,NEGR1,CPT1C,ICA1,IGF1,NKD1,IL6R,IL6ST,IL11RA,BRINP3,TUBB2B,LRRTM3,KCNA6,KCNC1,KCND3,KCNK1,KHK,TTYH2,LAMA2,LRRC4B,VWA5A,MAP2,MAP4,MATN2,MEIS2,AFF1,MMP16,MN1,CCDC80,ADAM22,NRBP2,MYBPC1,MYH7,LINC00672,LAYN,MYO7A,MYO9A,NEXMIF,NBL1,NCAM1,NEFM,NELL1,NFIA,NFIX,CNOT4,NPR2,DDR2,OGG1,P2RX7,ZNF827,PDE1A,PDE3A,PDE4D,PDGFRA,ENPP2,GPR173,PENK,CDK14,PGAM2,ABCB1,NLGN3,SERPINE2,SEMA5B,PKD1,ZFYVE21,PLCL1,PLEC,FTO,FXYD1,PLP1,PCDH18,PMP22,PRRX1,SDK2,SLC36A4,FAT3,POU6F1,PPARA,PPP1R1A,NKAIN4,PRKAR1B,EPDR1,MDGA2,CNTLN,PTH1R,PTN,PTPRD,PTPRE,PTPRG,PTPRZ1,RIPOR1,TMEM255A,FAT4,BEND5,ZMAT4,PRRT2,MORC4,SETD5,MYH14,ARMC5,ROBO1,ROBO2,ACER3,RIMKLA,TCP11L1,LRRK2,PLPPR3,MEG3,KCNIP3,ZNF354C,STX1B,SEMA6D,ATXN1,LRRTM4,PRCD,TNFRSF19,MRAS,SGK1,SCG5,SH3GL3,DOCK10,NTNG1,FHOD3,CNKSR2,NLGN1,ST8SIA1,DZIP1,CLSTN1,ZNF365,SLC1A3,SLC4A3,FAM81A,LIMS2,SLC6A9,SLC8A1,ARHGEF40,SLC12A4,SLC14A1,ELMO2,EFHD1,TET1,ZNF667,RIMS1,PALLD,PDZRN3,KDM4B,DOP1A,TRERF1,TNIK,ZCCHC24,SOX15,GLT8D1,SPP1,IQSEC2,ATP10B,CLSTN2,COLGALT2,SAMSN1,EPB41L3,NKAIN2,INKA2,STAC2,SULF2,ACSBG1,ARHGEF9,ANKRD12,TAL1,PDLIM2,ADGRL3,TBCEL,IQCE,EHBP1,TCF4,SATB2,TCF7,TCF12,USP22,SZT2,AZIN2,PSD3,TNS2,SIK3,CHST8,THRA,ENHO,TIE1,ASXL3,TLR4,DAAM2,KAT6B,TNS1,NPL,TPM2,TPM4,SYNPO2,TRPS1,RFTN2,TST,ZKSCAN5,TMEFF2,SLAIN1,FLRT2,PLEKHH2,PLPPR2,LMF1,VSNL1,WIPF1,WNT7A,XRCC4,ZNF23,ZNF32,KCNT2,SLC26A10,ZBTB38,ZNF184,EML6,ANKS1B,SLC30A4,LRP8,RGMA,TUBA1A,NAV3,PLD4,MVB12B,PLSCR4,FAM13C,MSRB3,ADAMTS10,SSPN,AAAS,PIANP,ST8SIA2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000 FaceBase_RNAseq 4.80E-28 2.45E-24 1.43E-26 1.31E-25 294 973 "TTYH1,SYN3,EMILIN3,ACTN2,NDRG2,ADCY2,CCDC85A,RNF157,PTCHD1,KIAA1324,SEMA6A,ALCAM,SRPX,ARHGAP20,PCDH10,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,APOC1,VAT1L,LGR5,CDK10,NCOA1,ASTN1,ADAM23,ADGRB2,ADGRB3,JAZF1,C1QC,CACNA1G,LDLRAD4,CACNA1A,CACNA2D1,THSD7A,VSTM2A,RUNX1T1,CBLN1,REPS2,LONRF2,KCNAB3,CDH8,EVI5L,CDO1,CRLF1,FOXN3,SLIT2,KIAA1549L,NRXN1,CLTB,IGLON5,ARHGEF6,PCYT1B,COL9A2,SLC4A8,ABI3BP,COX4I1,SLC35F1,FAM171B,CREB5,ANKRD44,AATK,SNCAIP,CSF1R,CSF2RA,FEZ1,ERC2,CTNND2,PYGO1,HDAC9,TOX,SCRN1,SPOCK2,DCC,B3GAT3,RUSC2,NTM,CCDC3,KBTBD11,DLG2,DMD,SHANK1,DRP2,DTNA,MAMLD1,ABCC9,EBF1,EDNRB,HEYL,SEMA3D,EGFR,RASA4,ELN,TMEM35A,EMX2,ENO2,EPB41L1,LRRC17,EPHA5,EPS8,APC2,ADGRV1,TUBB3,TUBB4A,ATP8A1,CHST15,FCGRT,FGF11,FGF12,SYT3,DPYSL4,TRIM16,NSG1,TPPP3,NRG3,TVP23A,FYB1,DKK3,JPH4,ARPP21,TMEM8B,ACSS1,PCDH17,CSDC2,PPARGC1A,NTNG2,ZNF276,GLDC,GLRB,PCDH11X,MAP7D2,GPM6B,TDRKH,NR3C1,GSN,MFSD2A,FAM107A,WIF1,RASSF8,TOX2,FRMD3,HLF,HPSE2,SYNPO,NEGR1,IL11RA,BRINP3,CREG2,LRRC4B,VWA5A,GPR155,IL17D,MEIS2,SRSF12,CD200,COMMD5,CCDC80,ADAM22,MSR1,NRBP2,THYN1,TAGLN3,NEXMIF,TCEAL5,NCAM2,NEFM,NELL1,NELL2,NFIA,NFIX,NPY,NPR2,NTRK2,CNTN3,PAX6,PCDH9,PDE1A,PDE4D,PENK,PGAM2,NLGN3,SERPINE2,SEMA5B,ZFYVE21,TMEM38A,PLCL1,FXYD1,SLC25A23,PLTP,TRHDE,FAT3,NXPH1,POU3F4,FSD1,POU6F1,IRX1,NKAIN4,PRKAR1B,MAPK10,PRODH,MDGA2,RAB3A,ACSS3,IQSEC3,ZCWPW1,ENOX1,ZNF493,BEND5,ZMAT4,PRRT2,RGS10,PRIMA1,ZFHX4,MYH14,RPL38,EMID1,LRRK2,MEG3,RTN1,STX1B,DGLUCY,CSRNP3,ATXN1,LRRTM4,MRAS,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A3,SLC6A9,SLC8A1,SMARCD3,PDZRN3,SOX2,ARHGAP26,NPAS3,CLSTN2,MAPK8IP3,DIP2A,ACSBG1,ZFR2,RHBDL3,ADAMTS17,PLCB1,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,UNC5D,ADGRL3,WSCD1,SATB2,CUX2,PHF24,TMEM151B,FAM189A1,PSD3,THRA,NR2E1,TNNT1,TRPS1,KCNE5,TST,UCHL1,SLAIN1,FLRT1,PLPPR2,TSPAN11,ZIC1,ZIC2,FMN2,LYPD6,TMEM237,DPYSL5,PMEPA1,CADM2,LRP8,SHD,STMN4,PCDH15,NAV3,TMEM163,WNK2,KLHDC1,PIANP,DPF3,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 5.30E-28 2.70E-24 1.57E-26 1.43E-25 137 328 "ABCF1,FMNL2,KLHL32,GALNT16,PCDH19,LTBP4,CDC42BPA,EPB41L5,PHYHD1,MADD,ASTN1,ATP6V1G2,KIF1A,ADGRB3,PROM1,CACNA1A,PTBP2,CDK11B,CDH2,CDH8,MAGI1,JAM2,KIAA1549L,NRXN2,C4orf33,CNTFR,IQCK,IGDCC3,FAM171B,FEZ1,ERC2,CTNND2,RIMS2,KATNAL2,JAKMIP2,RAB39B,DMD,CASP8AP2,MAMLD1,PLXNC1,EIF5,ELAVL2,ELAVL4,RGS17,C8orf37,EMX2,EPHA5,GPHN,ACSL4,TAOK3,ATP8A1,MED12L,FGF12,FGFR3,FHL1,KHDRBS3,FUT9,B3GAT1,ADGRA1,TPPP3,PHYHIPL,ILDR2,KIAA1841,GATM,PCDH17,PPARGC1A,DBF4,MAP7D2,GNAO1,GNG3,TDRKH,PCLO,CIT,RABL2A,SOX21,DDX19B,USP51,INSM1,TUBB2B,LRRTM1,KIF5C,KTN1,LSAMP,LSS,SCG3,NASP,NCAM2,NEFM,NOVA1,NTRK2,OPA1,GPR137C,PAK3,PAX6,PCDH9,SEMA5B,SLC25A23,FAT3,VPS13C,MDGA2,ELOVL2,EML5,PTPRZ1,FEZF2,RBBP6,RFX4,FBXW7,STX1B,SAFB,ATXN1,SOX6,ZFP30,KIF21A,PPM1E,ARX,FHOD3,NLGN1,GKAP1,LMO3,ZSCAN29,SYNE2,VPS13A,SYN1,CCDC173,AKTIP,NR2E1,KAT6B,PRMT8,FAM181B,RBFOX3,WNT7A,ZNF23,FMN2,REEP1,SPIRE1,GAL3ST3,NETO2" Coexpression Atlas BM Top 100 - spinal cord BM Top 100 - spinal cord Body Map 1.46E-27 7.45E-24 4.31E-26 3.92E-25 51 66 "ERMN,PLEKHH1,CARNS1,AQP4,SYNJ2,GYG2,VXN,CH25H,DCLK1,MAP4K4,CNTN1,ST18,OLIG1,CALN1,ARRDC4,EDNRB,OLIG2,GALNT15,GFAP,STON1,GPR37,SCIN,LIX1,KCNJ16,MAG,MBP,MOBP,MOG,NEFM,NEFH,NKX2-2,OLR1,ANLN,PMP2,KLK6,TMEM255A,RFX4,TMEM206,PAQR6,S100B,SALL1,SPP1,NKAIN2,TAC1,TF,SPX,UGT8,SLAIN1,P2RY12,CLDND1,SLC17A6" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.53E-27 7.79E-24 4.48E-26 4.08E-25 71 116 "ADCYAP1R1,UNC79,APBA2,APBB1,VAT1L,LGR5,SLC7A14,KIF1A,TTC9B,NRP2,INA,LONRF2,DCLK1,CHGB,RAB33A,PICK1,CRMP1,FEZ1,PLXNA4,NRSN1,SCRN1,SEZ6L2,KCNMB2,CEND1,CACNG3,FDFT1,FGF13,NSG2,NSG1,TPPP3,SYT17,GFRA1,GFRA2,C1QL1,RUNDC3A,STMN2,ARHGAP36,DISP2,LIX1,TUBB2B,KIF5A,KLC1,L1CAM,MAP6,TAGLN3,DDX25,MYT1,NCAM1,NELL2,NNAT,SLC10A4,GDAP1L1,SERPINE2,PLP1,PMP22,PROX1,ZMAT4,RET,RGS4,RTN1,SCG5,SNRPN,NFASC,SEPT3,STXBP1,SYT11,SYP,UCHL1,DPYSL5,STMN4,MVB12B" Coexpression Atlas Arv_SC-LF_2500_K5 AravindRamakr_StemCell-LF_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 1.81E-27 9.23E-24 5.28E-26 4.81E-25 333 1157 "DPF1,KCNH8,ASPHD1,SYN3,CSMD2,TMEM132B,ADCY2,ADCY8,GALNT13,PLEKHH1,UNC5A,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,DPP10,CNIH2,PPP4R4,TMEFF1,RASL11B,KIF1A,CARMIL3,RGS9,PROM1,GYG2,CACNA1G,HAP1,SYT6,BRSK2,MAP7,CBS,CLDN10,MTMR7,SYNGR3,CDH8,DLGAP1,CACNA2D2,CHGA,PLEKHB1,RAB3C,CHRNB2,DLGAP3,NRXN1,SLC24A2,FAM19A5,SULT4A1,CCDC151,IGLON5,COL9A1,COL9A3,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,SLC35F1,CRYBB1,LRIG1,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,ERC2,CTH,SEC14L5,KATNAL2,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,PARD6A,MTX3,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,E2F5,USH1C,ST8SIA3,SEZ6L2,ATL1,AASS,LINC00599,ELAVL2,SEZ6,ZNF391,TMEM74,PIPOX,CEND1,ADGRV1,FABP7,PPP1R1B,ZNF589,OLFM1,SPSB4,MAD2L2,HPCAL4,C1orf61,SYT3,CSPG5,B3GAT1,TVP23A,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,GABRG2,JPH4,SALL3,GAP43,ATP8A2,GCK,GCNT2,RUNDC3A,RND1,GLDC,PCDH11X,LUZP2,GNAL,GNG3,GNG4,GPM6B,B4GALNT4,GPR19,LPAR4,CECR2,GRIA4,GRIK5,GRIN1,ADAMTS8,GRM3,PTPN5,SOX21,LINGO1,PSIP1,RNFT2,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,HPCA,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,PLD5,IGSF1,ZNF678,RIPPLY2,TUBB2B,LRRTM3,KCND1,KCND2,KCNN1,KCNN2,KCNQ2,KIF5A,KIF5C,CYP27C1,LRRC4B,CAMK2N2,FGFBP3,C2orf80,NAT8L,CHST6,SCAMP5,CPNE9,JAKMIP3,SCG3,DDX25,MYCN,TCEAL5,BEX5,FXYD7,NAP1L2,NAP1L3,NASP,ZC3H12B,RCOR2,NEFM,NELL2,NNAT,NODAL,VWA2,NOS1,HCN1,NTRK3,GPR137C,ZDHHC22,PAH,PCSK2,NLGN3,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,PLP1,PSAT1,NECAB2,MAGEL2,EPB41L4B,PACSIN1,POU3F4,PPP2R2B,RAB39A,PRKCG,LAMA1,GDPD2,ZIK1,PTPRN,PTPRZ1,TMEM145,NKAIN1,ACSS3,ZNF793,FAM184A,ZNF493,KHDRBS2,ZMAT4,RET,RGS7,KIF7,RIT2,LGI2,RORB,MRAP2,RIMKLA,HUNK,RYR1,SALL1,DRAXIN,LRRTM4,TMEM200C,SCG5,SH3GL2,SH3GL3,PPM1E,SLITRK3,CNKSR2,SLC1A6,PREX2,LRRC55,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,TET1,ZNF667,MAST1,OGDHL,IGSF9B,INAVA,SNCB,SNRPN,UNC80,SOX2,SOX3,KIF21B,NMNAT2,LHFPL4,PEG10,BEX1,SSTR2,SOX21-AS1,STAC2,SEPT3,ZFR2,SYN1,ARC,SYP,SYT1,COBL,TAC1,TAC3,TACR1,UNC5D,WWC1,KLHL4,TMEM151B,FAM189A1,SLC19A3,PCDHB3,PCDHA3,PCDHA2,CCDC173,RNF175,TEX15,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,IL34,CA14,TUBB2A,RPRM,UCHL1,UGT8,VGF,VSNL1,RBFOX3,SLC13A3,KCNK12,ZIC2,ZIC3,KCNT2,ZNF138,DPYSL5,CADM2,XKR7,GAL3ST3,WNK3,JMJD1C,AP3B2,FAM198A,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.38E-27 1.22E-23 6.91E-26 6.29E-25 95 188 "TTYH1,ABAT,NDRG2,ADCYAP1R1,SPARCL1,SEMA6A,PCDH10,CCDC146,LRRC4C,ASCL1,PCDHGB4,ATP1A2,CA12,SPAG9,SEPT7,CDO1,CDR1,ADGRG1,CLU,QKI,CREB5,SNCAIP,LRIG1,NCAN,CST3,CTNND2,RASSF2,DBI,LYPD1,DPP6,DTNA,EDNRB,LRRC17,ADGRV1,FAM198B,FABP7,FGFR3,C1orf61,PDLIM5,CSPG5,PHYHIPL,ILDR2,GATM,HEPN1,DCLK2,GPM6A,GPM6B,HAS2,SCRG1,CFAP126,C2orf72,HES5,LIX1,LIFR,FGFBP3,MT3,NCAM1,NFIA,NFIX,NTRK2,ENPP2,SERPINE2,PLP1,PLXNB1,PMP2,FAT3,LRRN3,NKAIN4,HYDIN,MASP1,PTCH1,PTN,PTPRZ1,TMEM231,VEPH1,RFX4,KLHDC8A,WLS,SALL1,BCAN,SLC1A2,SLC1A3,SLC15A2,LIMCH1,SOX2,NPAS3,SMOC1,SULF2,MLC1,WWC1,VWA3A,TCF4,HEY1,SEZ6L,RGMA" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 8.32E-27 4.25E-23 2.40E-25 2.19E-24 68 110 "ABR,FMNL2,KIDINS220,ANK3,ATP2B1,CDK5R1,SCAPER,CACNA1B,BRSK2,RUNX1T1,INA,CDH8,NRXN1,NRXN2,VCAN,KIAA0408,SCRN1,BRINP1,DCC,NTM,KBTBD11,EDIL3,ELAVL4,STX2,SORBS1,NSG2,OGA,GAP43,DNER,PCDH17,TOX3,GNAO1,PCLO,CNTRL,STMN2,GRIA2,KIF3A,MEIS2,CD200,NCAM1,NNAT,PCDH9,PRKCB,PTPRN2,REV3L,ZFHX4,RTN1,SEMA6D,SCN2A,SCN3A,CASC3,SLC8A1,SCN3B,MYT1L,SOX11,MYCBP2,ERC1,SYT1,AGTPBP1,CLASP1,PUM2,ZFPM2,UBTF,CELF4,REEP1,TMEM178A,RTN4,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.37E-26 6.97E-23 3.91E-25 3.57E-24 78 139 "FMNL2,KLHL32,PLEKHH1,EPB41L5,PHYHD1,ASTN1,KIF1A,PROM1,CDK11B,CDH2,MAGI1,JAM2,LHX2,KIAA1549L,NRXN2,IGDCC3,NECTIN3,SLC35F1,SLITRK5,CTNND2,RIMS2,KATNAL2,JAKMIP2,RAB39B,DMD,MAMLD1,ELAVL2,ELAVL4,EMX2,FGFR3,FUT9,PHYHIPL,ILDR2,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,TDRKH,PCLO,SOX21,USP51,KTN1,PPM1L,SCG3,NASP,NEFM,NOVA1,NTRK2,GPR137C,PAK3,SEMA5B,GPSM2,SLC25A23,FAT3,DIRAS2,ELOVL2,EML5,FAM184A,ARID4A,FEZF2,RFX4,SOX6,HSPA4L,KIF21A,PPM1E,ARX,FHOD3,SYNE2,SYN1,TCF7L2,CCDC173,NR2E1,PRMT8,SLAIN1,FMN2,GAL3ST3,FZD3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.50E-26 7.62E-23 4.26E-25 3.88E-24 64 100 "KIAA1324,EPB41L5,ASCL1,ATP1A3,INA,CDH8,ADGRG1,SRSF11,JAM2,LHX2,IGDCC3,PLCH2,RIMS2,ST18,JAKMIP2,MAMLD1,ELAVL2,ELAVL4,EMX2,OLIG2,ADGRV1,FABP7,ZIC4,FOXG1,FUT9,ILDR2,SRRM4,GLDC,TOX3,MAP7D2,GPM6A,GPM6B,CECR2,STMN2,RNF165,SOX21,CELF3,TOX2,IGFBPL1,SCG3,RSPO2,MYT1,NOVA1,NRCAM,PAX6,PRTG,SEMA5B,IRX1,ELOVL2,EML5,PTPRZ1,FEZF2,RFX4,LINC00461,HSPA4L,KIF21A,ARX,SYN1,NR2E1,PRMT8,ZIC1,ZIC2,ZIC3,DPYSL5" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.63E-26 8.32E-23 4.62E-25 4.21E-24 258 832 "DPF1,CPNE2,RALGAPA1,ABCF1,SYN3,ACLY,C3orf14,NCKAP5,NDRG3,FMNL2,KLHL32,ADCYAP1R1,BRAP,KIAA1211,TXNDC16,CC2D2A,MRTFA,PPFIA1,EPB41L5,APLP1,PHYHD1,KIAA1614,ASTN1,CCDC181,ATP6V1G2,ADAM23,ADGRB3,PROM1,ARHGEF7,CACNA1A,CACNA2D1,CACNB2,THSD7A,PTBP2,CANX,CERS5,SLC16A4,CDK11B,LONRF2,CDH2,CDH8,MAGI1,CHN1,JAM2,LHX2,KIAA1549L,COG1,C4orf33,QKI,TMEM184B,HECTD1,NIPBL,IQCK,SLC4A8,IFFO1,IGDCC3,NECTIN3,PREPL,RNF14,NCOR1,CLIP3,ERC2,PHF14,CTNND2,ARHGAP32,KATNAL2,TOX,TBC1D5,LIN54,KIAA0586,IST1,DGKB,GIT2,ARMCX4,JAKMIP2,PLEKHM1,DDX46,DMD,CASP8AP2,ATN1,PDCD6IP,MAMLD1,WDPCP,KLHL5,EFNA3,PLXNC1,ELAVL2,ELAVL4,DCTN4,EMX2,EPHA5,GPHN,RTN3,NSRP1,ACSL4,ATP8A1,FGF12,FGFR3,CAMSAP1,FHL1,CAP2,EVL,TMEM175,ZNF605,FUT9,B3GAT1,ADGRA1,PHYHIPL,GABBR1,ILDR2,NEK6,HIGD1B,C15orf41,KIAA1841,MMADHC,PPARGC1A,TCERG1,DBF4,GLI2,MAP7D2,GNAO1,GNG3,TDRKH,PCLO,RFFL,GRIK4,CIT,KIF3A,RABL2A,SOX21,HPCA,USP51,ZNF546,INSM1,TUBB2B,LRRTM1,KCNN3,KIF2A,KIF5C,STXBP5,KTN1,LSAMP,TM6SF1,PPM1L,POC1B,SESN3,SCG3,MXI1,MYO5A,MYO9A,NASP,NEFM,NEK1,CNOT4,NOVA1,NTRK2,NUMA1,OCRL,ODF2,GPR137C,PAK3,PAX6,GNG2,FAM98B,SEMA5B,CCSER2,PLP1,SLC25A23,ZNF426,MTRF1L,PURG,TRHDE,NECAB2,RETREG2,FAT3,SH3KBP1,PPP2R5C,SLC22A23,GON4L,MDGA2,ANKHD1,ELOVL2,EML5,PTPRZ1,PTX3,FAM184A,ARID4A,FEZF2,RBBP6,GTDC1,RFX4,DCUN1D2,ARMC5,ROBO2,FBXW7,CLIP1,SAFB,FNIP1,ZFP2,SOX6,KIF21A,PPM1E,ARX,FHOD3,R3HDM2,NLGN1,ST3GAL3,ANKRD6,WDR47,YPEL4,CCDC88A,BTBD7,EPC1,GKAP1,BDP1,ERC1,NPAS3,LMO3,SRPK2,TAB2,TROVE2,NEK4,SEPT8,SYNE2,VPS13A,C3orf70,SYN1,MLST8,KIAA1107,AGTPBP1,DMXL2,TCF7L2,RPGRIP1L,CCDC173,NR2E1,ERCC6L2,C9orf85,PRMT8,STXBP4,RBFOX3,WNT7A,ZNF23,TRIM9,ZFP41,FMN2,ZBTB38,REEP1,ZNF184,UPF3A,LRP8,RNF103,GAL3ST3,TMEM163,ST7,HNRNPA3,ZNF248,NETO2,RNF146" Coexpression Atlas PCBC_SC_1000 Progenitor-Cell-Biology-Consortium_StemCell_top-relative-expression-ranked_1000 PCBC 1.92E-26 9.80E-23 5.42E-25 4.94E-24 294 993 "SYN3,CSMD2,TMEM132B,ADCY2,ADCY5,GALNT13,ADD2,UNC5A,PTCHD1,NLGN4X,SEMA6A,PDZD4,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,AZGP1,ADGRB1,LDHD,GYG2,CACNA1G,HAP1,SYT6,BRSK2,MAP7,CBS,CLDN10,CCK,MTMR7,SYNGR3,CDH8,DLGAP1,CACNA2D2,CHGA,RAB3C,CHRNB2,DLGAP3,SLC24A2,FAM189A2,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,RIMS2,FAM131B,SEC14L5,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,HS3ST4,HS3ST2,CALN1,FAM57B,SLC25A18,USH1C,ST8SIA3,AASS,LINC00599,ELAVL2,RASGRP2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,ZNF589,OLFM1,ACTL6B,HPCAL4,C1orf61,SYT3,CSPG5,B3GAT1,TMEM151A,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,SALL3,ATP8A2,SRRM4,GFRA2,GLDC,PCDH11X,GNAL,GNAO1,GNG3,GNG4,GPM6A,GPM6B,GPR19,LPAR4,CECR2,GRIA4,GRIK5,GRIN1,ADAMTS8,GRM3,GRM8,SOX21,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,C9orf129,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,PLD5,IGSF1,ITGAM,KCNA6,KCND1,KCND2,KCNJ11,KCNN1,KCNN2,KCNN3,KCNQ2,KHK,KIF5A,KIF5C,CAMK2N2,FGFBP3,MATK,SYT9,CHST6,SCAMP5,CPNE9,ADAM22,SCG3,DDX25,MYCN,TCEAL5,FXYD7,NAP1L2,NAP1L3,NASP,RCOR2,NEFM,NELL2,NNAT,NODAL,NOS1,NPTX1,NTRK3,ZDHHC22,PAH,PCDH8,PCSK2,NLGN3,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PLP1,NECAB2,MAGEL2,SEPT4,EPB41L4B,PACSIN1,FA2H,POU3F4,PPM1B,PPP1R1A,PPP2R2B,PPP2R2C,NKAIN4,PRKCB,RAB39A,PRKCG,PRODH,LAMA1,GDPD2,PTPRD,PTPRN,PTPRO,PTPRZ1,TMEM145,NKAIN1,ZMAT4,RET,RGS7,PRIMA1,RIT2,RORB,MRAP2,SYNDIG1,HUNK,RYR1,SALL1,SCN4B,TMEM200C,SCG5,SH3GL2,SH3GL3,PPM1E,CNKSR2,SLC1A6,LRRC55,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,IGSF9B,SNCB,SNRPN,SOX2,SOX3,SOX15,NMNAT2,LHFPL4,SSTR2,SOX21-AS1,SEPT3,ACSBG1,ABCC8,ZFR2,RHBDL3,SYN1,ARC,SYN2,SYP,SYT1,COBL,SYT4,TAC1,TAC3,UNC5D,CNTN2,KLHL4,TMEM151B,FAM189A1,RNF175,CHST8,THBS4,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,PIK3R5,TPD52,CA14,RPRM,UCHL1,UGT8,VGF,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,DPYSL5,SLC30A3,CADM2,GAL3ST3,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.11E-26 1.08E-22 5.91E-25 5.39E-24 289 971 "TTYH1,EMILIN3,NCKAP5,ACTN2,NDRG2,GALNT16,ADCY2,ADCY8,RNF157,PTCHD1,KIAA1324,C1QTNF1,SRPX,ARHGAP20,LTBP4,GPRASP2,PPFIA2,APLP1,MAGEE2,LRRC4C,CDK10,PDE8B,NCOA1,ASTN1,ADAM23,TTLL9,ADGRB2,ADGRB3,BARD1,JAZF1,C1QC,CACNA1G,LDLRAD4,CACNA1A,CACNA2D1,CAMK2A,SLC25A14,VSTM2A,RUNX1T1,REPS2,LONRF2,KCNAB3,CDH8,EVI5L,CDO1,CRLF1,SRSF11,FOXN3,SLIT2,NRXN3,PPT2,KIAA1549L,NRXN1,CLTB,IGLON5,ARHGEF6,CNTFR,WHRN,COL9A2,SLC4A8,ABI3BP,SLC35F1,CREB5,ANKRD44,AATK,CSF1,CSF1R,CSF2RA,FEZ1,LRRC3B,ERC2,ST18,HDAC9,MYADM,ARHGAP24,TOX,SCRN1,SPOCK2,DCC,C8orf34,RUSC2,SV2A,CCDC3,DLG2,DMD,SHANK1,DRP2,DTNA,MAMLD1,ABCC9,SNX29,HEYL,SEMA3D,EFNA3,EGFR,RASA4,RGS17,ELN,TMEM35A,ENO2,EPB41L1,LRRC23,LRRC17,EPHA5,EPS8,APC2,CHST15,FCGRT,FGF11,FGF12,SEMA6C,DPYSL4,TRIM16,STAU2,TPPP3,NRG3,TVP23A,FYB1,ZMAT1,JPH4,ARPP21,TMEM8B,ACSS1,PCDH17,CSDC2,PPARGC1A,LYVE1,ZNF276,GLRB,PCDH11X,GNG4,GPM6B,GRIA1,GRIK4,NR3C1,GSN,MFSD2A,FAM107A,WIF1,FRMD3,SYNPO,NEGR1,IL11RA,BRINP3,ZNF385B,METTL21A,KLHL23,KCNK1,KCNN3,CREG2,VWA5A,GPR155,IL17D,MEIS1,MEIS2,SRSF12,CD200,CCDC80,ADAM22,MSR1,NRBP2,TAGLN3,RSPO2,NEXMIF,TCEAL5,FXYD7,NCAM2,NELL1,NELL2,NFIA,NFIX,NPR2,NRGN,NTRK2,OGG1,GPR137C,CNTN3,PCDH9,PDE1A,PDE4D,NLGN3,SERPINE2,SEMA5B,TMEM38A,PLCL1,FXYD1,PMP22,TRHDE,PRRX1,SDK2,MAGEL2,EPB41L4B,FAT3,NXPH1,POU6F1,NKAIN4,PRKAR1B,MAPK10,PRODH,MASP1,DEF8,MDGA2,CNTLN,PTPRD,RAB3A,ACSS3,IQSEC3,RAP1GAP,ZCWPW1,ENOX1,ZNF493,BEND5,ZMAT4,PRRT2,ZFHX4,MYH14,MRAP2,BAALC,PRR5L,STK32B,EMID1,LRRK2,MEG3,STX1B,DGLUCY,ATXN1,LRRTM4,MRAS,SH3GL2,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A3,FAM214B,SLC6A9,SLC8A1,SMARCD3,PDZRN3,NPAS3,CLSTN2,DIP2A,ZFR2,RHBDL3,ADAMTS17,PLCB1,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,UNC5D,ADGRL3,ACSL6,SATB2,CUX2,AZIN2,PHF24,FAM189A1,PSD3,TMEM121,THRA,PIK3R5,SYNPO2,TRPS1,KCNE5,SSBP2,FLRT1,TSPAN11,TRIM9,FMN2,NDRG4,LYPD6,EML6,PMEPA1,CADM2,LRP8,STMN4,PCDH15,NAV3,TMEM163,WNK2,KLHDC1,DPF3,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.30E-26 1.17E-22 6.41E-25 5.84E-24 101 212 "TTYH1,NDRG2,SLITRK1,MTUS1,ANK2,SHTN1,ASCL1,ATP2B2,CARMIL3,DIRAS1,HAP1,CDC25B,ADGRG1,SRSF11,NRXN3,COL4A5,SLC35F1,NCAN,CNTNAP2,SLITRK5,ST18,RUBCN,SCRN1,DNAL1,MYEF2,FBXO25,SRGAP3,DLX1,DTNA,EDNRB,FSD1L,ELAVL3,OLIG2,EPHB1,ADGRV1,FABP7,TUBB3,FOXG1,DPYSL4,SPECC1,GAD1,GAD2,SRRM4,ACSS1,PCDH11X,GPM6A,GPM6B,STMN2,GRIK2,NR3C1,RNF165,MFSD2A,CELF3,TOX2,FRMD5,IGFBPL1,CELF5,ATCAY,HES5,MAP2,MBP,SHC3,MYT1,NELL2,NFIA,POU3F4,PKIA,MAPK10,GDPD1,MEG3,RTN1,CCDC112,LINC00461,HSPA4L,SCG5,FAM214B,MAST1,SNAP25,SOX2,SOX5,LHFPL4,NPAS3,SEPT3,GSE1,KLHL7,SYT11,FGD4,SYP,AHCYL2,TUB,MGAT5B,TSPAN11,ZIC1,ZIC3,CELF4,DPYSL5,STMN4,STOX2,WNK2,FZD3,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 3.09E-26 1.58E-22 8.57E-25 7.81E-24 90 177 "TTYH1,SLITRK1,ASCL1,ZBTB10,ATP2B2,ARHGEF7,DIRAS1,HAP1,CDC25B,ARHGAP33,ADGRG1,SRSF11,SLIT2,COL4A5,SLC35F1,CRMP1,NCAN,CNTNAP2,SLITRK5,ST18,KATNAL2,SCRN1,DCC,SRGAP3,FSD1L,ELAVL3,OLIG2,APC2,ADGRV1,CLVS1,FABP7,ZIC4,SPSB4,FOXG1,NSG2,SRRM4,PCDH11X,GPM6A,GPM6B,STMN2,GRIK2,RNF165,MFSD2A,RNFT2,CELF3,TOX2,FRMD5,IGFBPL1,ATCAY,ZIC5,HES5,MAP2,SHC3,TAGLN3,MYT1,NELL2,NRCAM,POU3F4,PKIA,MAPK10,PROX1,RAD51D,GSTCD,CCDC25,RXRA,LINC00461,HSPA4L,SCG5,PEX26,MAST1,SNAP25,NPAS3,TTBK2,SYT11,FGD4,WSCD1,ACSL6,CUX2,FRYL,AHCYL2,UCHL1,MGAT5B,ZIC1,ZIC3,DPYSL5,STMN4,STOX2,WNK2,FZD3,SPATA13" Coexpression Atlas BM Top 100 - putamen BM Top 100 - putamen Body Map 5.01E-26 2.56E-22 1.38E-24 1.26E-23 54 76 "SLC12A5,ERMN,ADORA2A,CPNE5,ATP2B1,RGS9,CA12,CACNA1E,CALB1,CDR1,SYNPR,LHX2,NGEF,CNR1,SLC32A1,DGKB,PLPPR4,ST8SIA3,PPP1R1B,FOXG1,NSG2,GABRA2,GABRA4,GAD1,GAD2,ARPP21,CPLX1,CYP46A1,GNAL,PTPN5,WIF1,HPCA,CELF5,SOWAHA,KCNJ4,KCNQ2,MOBP,NRGN,GPR88,PENK,PPP3CA,PRKCB,SCN2A,SCN4B,SLC1A2,DDN,SST,NCDN,TAC1,FBXL16,RASD2,LAMP5,KCNAB1,MPPE1" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1 Gudmap RNAseq 5.19E-26 2.65E-22 1.42E-24 1.30E-23 331 1168 "DPF1,EMILIN3,KDM5D,FMNL2,GALNT16,ADCY2,SORCS1,NME5,SORCS2,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PDZD4,DOC2A,LRCH2,ANK2,SMIM29,PPFIA2,APBB2,MAGEE2,UPRT,CACHD1,LGR5,TMEM263,IGDCC4,ARHGAP5,NCOA1,RASL11B,ASTN1,DDX3Y,ZNF583,N4BP2L1,DOCK11,ADGRB2,BBS2,SEC11C,BCHE,DST,JAZF1,SGCE,CACNA1G,RAB29,LDLRAD4,CA12,CACNA2D1,CAMK2D,RUNX1T1,ARHGEF25,LDB2,CDK11B,SEPT7,LONRF2,DCLK1,EVI5L,CCPG1,CRLF1,NUMBL,JAM2,MYL6B,ABI3BP,MYRIP,ZNF521,CNRIP1,SLC35F1,FAM171B,CREM,ENTPD4,CREB5,ANKRD44,CLIP3,SNCAIP,CSF1,TENM4,CSF2RA,FEZ1,IPCEF1,VCAN,SOCS5,PLCXD3,PNPLA8,CFAP61,PYGO1,BOC,HDAC9,ARHGAP24,TOX,ZFYVE16,BRINP1,SNAP91,NTM,RABGAP1L,DMD,DNM1,SHANK1,EDN3,EDNRA,SEMA3D,TMTC1,EGFR,SORBS3,CERCAM,RGS17,ELN,EML1,CALCRL,EPS8,DENND4A,KATNAL1,HSPA12B,WAC,FABP7,CORO2B,EFEMP1,MED12L,FGF12,FGFR1,FHL1,SCARA3,FLNC,SGIP1,AFF2,COQ5,TMEM175,WDR83,SMC2,USP21,NPTN,GPR153,FUT9,TMEM151A,DKK3,GABRA1,IQGAP2,GAP43,ACSS1,GATM,GFRA2,FREM1,PCDH17,CSDC2,GHR,HPGDS,GLRB,GNAO1,GPM6A,GPM6B,GPR19,GRK4,GRIA4,GRIK1,PRDM5,LINGO1,ADAMTS6,SLC2A6,IRAK3,RASSF8,HAS2,INSYN1,SYNPO,CFAP126,NEGR1,SMAP1,LRRCC1,DIPK1A,KCNA6,KCNC1,KCNJ16,STXBP5,LAMA2,LAMP2,SYTL4,VWA5A,HECTD2,LSAMP,SMAD9,MAP2,MATN2,MEF2C,MMP16,MN1,SAMD5,ADAM22,NRBP2,MYBPC1,MYO7A,NBL1,NCAM1,NDUFA5,NEFM,NELL1,NFIA,CNOT4,NPY,NPR2,DDR2,NUCB2,PCSK5,PDE4D,ENPP2,PENK,CDK14,SEMA5B,TMEM38A,GPSM2,PLP1,PCDH18,PURG,PMP22,PRRX1,SDK2,SLC36A4,FAT3,PPP3CC,NKAIN4,EPDR1,PROX1,MASP1,CNTLN,MTMR10,PTH1R,PXK,TMEM260,PTPRD,PTPRE,PTPRZ1,PTX3,FAT4,ARID4A,BEND5,PRRT2,MORC4,RGS10,RNASEL,DCUN1D2,SETD5,ROBO1,ROBO2,RIMKLA,TCP11L1,MEG3,KCNIP3,CCDC112,SEMA6D,SCN2B,PRCD,FNIP1,ELMOD1,ZFP2,MRAS,ZFP30,PPP1R9A,SH3GL3,NTNG1,CHD9,FHOD3,NLGN1,DZIP1,FAM81A,BTBD3,ARHGEF40,CCDC88A,TET1,SLIT1,GKAP1,SMARCD3,RCOR3,RIMS1,MBD5,PALLD,PDZRN3,SCN3B,DOP1A,TNIK,CLUAP1,GLT8D1,SPP1,RAP1GAP2,CLSTN2,COLGALT2,SST,EPB41L3,INKA2,SULF2,ARHGEF9,C3orf70,ANKRD12,FAM208A,ADGRL3,AGTPBP1,EHBP1,TCF4,PSD3,ZFPM2,ITGB3BP,ASXL3,TNNT1,NPL,TPM2,SYNPO2,PRMT8,LRRC24,TRPS1,SSBP2,RFTN2,TST,SGK3,SLAIN1,FLRT2,PLEKHH2,VSNL1,WNT7A,ZNF23,KCNT2,REEP1,UPF3A,SLC30A4,PMEPA1,LRP8,EVI5,ADAMTS9,NAV3,PPP1R3F,SMIM8,CERS6,RNF170,ADAMTS10,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K3 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 5.31E-26 2.71E-22 1.45E-24 1.32E-23 70 118 "PLEKHH1,EPB41L5,ZFYVE28,KIF1A,ADAM23,PROM1,DST,THSD7A,CDK11B,LHX2,KIAA1549L,NRXN2,C4orf33,SLC35F1,FAM171B,CLIP3,SUSD5,CTNND2,RIMS2,KATNAL2,JAKMIP2,RAB39B,ELAVL2,EMX2,FHL1,FUT9,PHYHIPL,GABRB3,ILDR2,HIGD1B,GATM,PPARGC1A,GLDC,TOX3,MAP7D2,GNG3,GPD2,PCLO,RFFL,SOX21,USP51,LRRTM1,KTN1,PPM1L,NOVA1,PAK3,PAX6,SLC25A23,MASP1,ELOVL2,PTPRZ1,FEZF2,RFX4,FBXW7,ZFP30,KIF21A,ARX,FHOD3,TET1,LMO3,SYN1,TCF7L2,NR2E1,PRMT8,STXBP4,SLAIN1,RBFOX3,ZNF23,TMEM163,WNK3" Coexpression Atlas BM Top 100 - cerebellum BM Top 100 - cerebellum Body Map 5.58E-26 2.84E-22 1.51E-24 1.38E-23 51 69 "SLC12A5,TRMT9B,PPFIA4,CACNA1A,CALB1,CBLN1,DLGAP1,CDR1,CHGB,SYNPR,MICAL2,ST18,CALN1,LINC00599,EN2,ETV1,MEGF11,GABRA1,GABRG2,GAD1,SRRM4,STMN2,GRM1,CELF5,KCNA1,KCNC1,KCND2,KCNQ2,MAP4,NEUROD1,NPTX1,OPCML,PAX6,PDE1A,DIRAS2,RELN,RIT2,SCN2A,CNKSR2,SNAP25,SYT1,SYT4,MTCL1,ZFPM2,TIAM1,VSNL1,ZIC1,ZIC2,FSTL5,CA10,TMEM178A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.60E-26 2.85E-22 1.51E-24 1.38E-23 66 107 "SLITRK1,DPP10,ANK2,VAT1L,SLC7A14,ASCL1,ASPH,ADGRB3,ARHGEF7,BRSK2,LGI1,CHGB,CNR1,CNTN1,AKAP6,MYRIP,CRMP1,NRSN1,ST18,SCRN1,DNAJC6,SNAP91,GRIN3A,ST8SIA3,ELAVL2,ELAVL4,CLVS1,FABP7,GABRB3,GAP43,DNER,GFRA2,GPR22,STMN2,FAM19A2,INSM1,KCNQ2,KIF5A,KIF5C,SYTL4,MAP4,MAPT,NCAM2,NEFM,NTRK2,PIRT,SLC10A4,DUSP26,SERPINI1,NALCN,PLP1,MAPK10,PRPH,RET,RGS4,RTN1,NAPB,SNAP25,UNC80,SCN3B,C11orf87,SYT11,SYT4,TMEFF2,FSTL5,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkB_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.13E-25 5.74E-22 3.02E-24 2.75E-23 49 65 "SLITRK1,ASCL1,CACNA1A,INA,SEPT7,REPS2,CDH8,NRXN2,CNTN1,PHACTR3,ERC2,NTM,OLIG1,ELAVL4,EN2,OLIG2,FABP7,TAOK3,C1orf61,NSG2,CSPG5,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,SCRG1,NCAM1,NOVA1,KSR2,OPCML,PDGFRA,GPR85,TMOD2,GDAP1L1,PMP2,NXPH1,LRRN3,MDGA2,RTN1,S100B,SCN2A,SCN3A,BCAN,MYT1L,SOX10,TMOD1,CELF4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.16E-25 5.90E-22 3.09E-24 2.81E-23 248 798 "ABAT,METAP1D,FMNL2,ADCYAP1R1,AXIN2,PNMA8B,KLHL13,NR0B1,CC2D2A,ALAD,SPARCL1,ALCAM,ABCD2,ARHGAP20,LTBP4,KCNT1,LRCH2,LCORL,GPAM,APOC1,CACHD1,LRRC4C,SHTN1,LGR5,CDC14B,PPP4R4,IGDCC4,PDE8B,CAPRIN2,NUMB,INSYN2B,TMEM108,SLC4A4,ATP2B3,RNF182,BCHE,RGS11,CACNA1G,WASF1,MYRF,CACNA1D,CACNB2,CALB1,KALRN,RUNX1T1,ARHGEF25,REPS2,DCLK1,MAGI1,CHRM4,SLIT2,CLU,CNTFR,AKAP5,ABI3BP,ZNF521,CLIP3,SNCAIP,TENM4,ATRNL1,VCAN,PLXNA4,BOC,DOCK4,DAPK1,ARMCX2,DCT,MAGI2,RHOBTB1,SV2A,SRGAP3,DLG4,DNM1,CDON,DRP2,ABCC9,E2F6,TSPAN5,EDNRA,SEMA3D,KLHL5,EGFR,PLXNC1,C8orf37,EMX2,EPB41L1,LRRC17,MTSS1L,NRN1,ABCA8,FAM198B,FABP7,DLC1,CHST15,OLFM1,CAP2,PCYOX1,FLNC,AFF2,ST6GALNAC3,NSG1,GABRA4,GABRB1,TRAF3IP2,DENND2A,NEK6,SEPT9,GATM,NEU3,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,GPM6B,GPR37,GRIA4,GRIK3,GUCY1A2,GUCY1A1,GUCY1B1,HPSE2,TCEAL6,SHISA6,IGF1,NKD1,PLD5,KCND2,KLHL23,LAMP2,SYTL4,MAP2,MARK1,MATN2,MEIS1,KITLG,MOV10,SESN3,CCDC80,MTR,MYBPC1,LAYN,NEXMIF,NCAM1,NELL1,NELL2,NFIA,NME4,NPR2,NUCB2,PCDH9,PDE1A,PDGFRA,CDK14,SERPINI1,PIK3R1,FXYD1,PLP1,PCDH18,PMP22,PRRX1,FAT3,SH3KBP1,PRKCB,LAMA1,GDPD2,CNTLN,PTN,PTPN13,TMEM255A,FAT4,ZCWPW1,ZFHX4,RAVER2,ROBO2,TMEM206,LGR4,MEG3,HUNK,KCNIP1,ZNF354C,CCDC112,SEMA6D,SATB1,SCN2A,PRCD,TNFRSF19,SOX6,STUM,MRAS,KIF27,RASA3,ZFP30,CNKSR2,ST8SIA1,DZIP1,SLC4A3,PKNOX2,SCMH1,ZNF667,PALLD,PDZD2,TNIK,ZCCHC24,KDM3A,UHRF1BP1L,PEG10,TSPYL2,NPAS3,LHPP,SMOC1,EPB41L3,ST5,SULF2,ADAMTS17,ADGRL3,ZEB1,RPGRIP1L,TCF12,PSD3,OBSL1,CCDC173,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,TNNT1,ZNF346,TRPS1,FNDC5,TST,AMOT,UCHL1,FLRT2,PLEKHH2,VSNL1,ZFP37,ZNF711,LYPD6,PMEPA1,NAV2,KCNAB1,WNK3,FRMD6,DPF3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.21E-25 6.19E-22 3.22E-24 2.94E-23 250 807 "RALGAPA1,EMILIN3,ADCY5,SORCS1,USP31,PCDH19,TBC1D14,TAOK1,PCDH10,FAM135A,SYT13,DPP10,ANK3,APAF1,APC,PHYHD1,LGR5,CASK,ASTN1,INSYN2B,SLC4A4,BARD1,BCHE,NRP2,BMP7,CDK5R1,DST,CACNA1B,CACNA2D1,KALRN,CANX,VSTM2A,CH25H,RUNX1T1,INA,CDC27,CDH10,ZMYM4,CHGB,SOCS6,RAB3C,CNR1,SLC35F1,FAM171B,PREPL,CRMP1,ANKRD44,TENM4,VCAN,CTNND2,PYGO1,HDAC9,TOX,TM9SF4,TMEM170A,JAKMIP2,ELMO1,MFAP3L,ARNT2,KBTBD11,HS3ST4,DNM2,DPYSL2,DRD1,DYRK1A,ABCC9,EDN3,EDNRA,EDNRB,HIPK3,SEMA3D,EGFR,ELAVL2,CALCRL,VPS13B,EPHA5,ETV1,EYA1,TMEM132C,TUBB3,EFEMP1,DLC1,KIAA1109,FGF13,SUCO,MEX3B,CAP2,FOXF2,SGIP1,SMC2,USP21,CELF1,DACH2,OGA,DKK3,MEGF10,GABRA3,CHL1,GABRB1,AHCYL1,IQGAP2,SYT17,DNER,GFRA1,GFRA2,PCDH17,GHR,PPARGC1A,GLRB,TOX3,PCDH11X,FERMT2,LPAR4,RAPGEF4,STMN2,GRIA2,GRM3,GRM7,GUCY1A1,GUCY1B1,WIF1,RASSF8,KLF12,ZDHHC15,IFI16,IGF1,RBPJ,IL6ST,LRRTM3,ITGAV,KCND3,KCNMA1,KIF5C,LIFR,LIMS1,ASPRV1,MAP4,MARK1,CHIC1,KITLG,PPM1L,MKLN1,MMP16,RSPO2,NAP1L2,NASP,NDP,NEFM,NFIA,NFIX,NOVA1,NPTX2,CLDN11,PAK3,CNTN3,PDE3A,PDGFRA,GPR85,TMOD2,NLGN3,PIK3C2A,PCDH18,TRHDE,PRRX1,FAT3,KANSL1,NKAIN4,PRKAR1B,MAPK9,MAPK10,PRPH,PTPRD,PTPRG,PTPRZ1,TMEM255A,FAT4,RBBP6,ZMAT4,TSPY26P,REV3L,KLHL11,ZFHX4,SETD5,ROBO1,RPE,LGR4,RTN1,RYR3,SALL1,SATB1,CSRNP3,SCN3A,LRRTM4,TNFRSF19,ZFP2,NTNG1,ST8SIA1,DZIP1,RUFY2,SLC12A2,NAPB,SLC15A2,CXXC4,SNAP25,PDZD2,SOX2,ZHX3,MYCBP2,PEG10,KIF1B,NPAS3,CLASP2,TROVE2,SMOC1,EPB41L3,ELOVL4,NEK4,FGD4,ARHGEF9,VPS13A,MTCL1,PJA1,DNMBP,CAMSAP2,ADGRL3,AGTPBP1,FBXW11,TBL1X,CLASP1,PCDHB7,PCDHB3,NSD1,HIF3A,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRIO,TRPS1,CADM1,RPRM,WRN,FMN2,FAM13C,NUP214,ZNF248,MSRB3,SOCS4,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.31E-25 6.67E-22 3.46E-24 3.15E-23 136 340 "TTYH1,SLITRK1,PTCHD1,WDR35,MAGEE2,SHTN1,ASCL1,ATP2B2,CARMIL3,JAZF1,DIRAS1,HAP1,VSTM2A,C1orf52,CDC25B,ADGRG1,SRSF11,SLIT2,NRXN3,DNAJB5,IGLON5,ARHGEF6,WHRN,COL4A5,CRMP1,AATK,NCAN,PHF19,SCRN1,DCC,MYEF2,KBTBD11,DLX1,DTNA,FSD1L,ELAVL3,OLIG2,ENO2,EPHB1,APC2,ADGRV1,FABP7,ZIC4,TUBB3,SPSB4,FOXG1,SEMA6C,AFF2,GAD1,SRRM4,ACSS1,RUNDC3A,DCLK2,GPM6B,STMN2,GRIK2,RNF165,RNFT2,CELF3,TOX2,FRMD5,KLF12,BACH2,IGFBPL1,CELF5,ATCAY,ZIC5,HES5,BRINP3,KCNH2,L1CAM,MAP2,SHC3,KITLG,MSI1,ADAM22,TAGLN3,LINC00672,MYT1,NNAT,SLC11A2,NRCAM,PGAM2,PLXNB1,SPATA6,MAPK10,RAD51D,GAL3ST4,GSTCD,TMEM206,SGSM1,ADAL,MEG3,RTKN,CCDC112,CSRNP3,LRRTM4,ASRGL1,SCG5,FBXO11,SLC1A3,FAM214B,CXXC4,MAST1,TMCC1,SOX5,SOX11,LHFPL4,KIF1B,NPAS3,CLSTN2,GSE1,SYT11,RHBDL3,SYP,ASTN2,TACC1,SEMA4A,TMEM178B,ACSL6,CUX2,TRIM2,PSD3,FRYL,AHCYL2,THRA,TUB,MGAT5B,ZIC1,ZIC3,DPYSL5,STMN4,WNK2,FZD3,SPATA13,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.64E-25 8.37E-22 4.32E-24 3.93E-23 76 137 "NCKAP5,ADCYAP1R1,PLEKHH1,KIAA1211,EPB41L5,KIF1A,PROM1,HAP1,CDH2,CDH8,JAM2,NRXN2,QKI,IGDCC3,SLC35F1,CNTNAP2,CTNND2,RIMS2,ST18,JAKMIP2,SRGAP3,RAB39B,MAMLD1,PLXNC1,ELAVL2,ELAVL4,FABP7,FUT9,B3GAT1,PHYHIPL,ILDR2,KIAA1841,PPARGC1A,MAP7D2,GNG3,TDRKH,PCLO,RNF165,SOX21,USP51,INSM1,TUBB2B,KIF5C,LSAMP,PPM1L,SCG3,NELL2,NOVA1,GPR137C,PAK3,SEMA5B,GDPD1,ELOVL2,EML5,PTPRZ1,RFX4,ZFP2,SOX6,HSPA4L,KIF21A,PPM1E,ARX,SLC1A2,KIF1B,NPAS3,SYNE2,SYN1,NR2E1,FAM181B,RBFOX3,WNT7A,ZFP41,REEP1,STOX2,RSPRY1,SPATA13" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500 Gudmap RNAseq 1.90E-25 9.71E-22 4.98E-24 4.54E-23 404 1522 "DPF1,EMILIN3,KDM5D,FMNL2,GALNT16,ADCY2,SORCS1,NME5,SORCS2,C1QTNF1,ADGRF5,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PDZD4,DOC2A,LRCH2,ANK2,SMIM29,PPFIA2,APBB2,MAGEE2,UPRT,CACHD1,LGR5,TMEM263,IGDCC4,ARHGAP5,PDE8B,NCOA1,RASL11B,ASTN1,DDX3Y,ZNF583,N4BP2L1,MYOM1,DOCK11,ADGRB2,BBS2,SEC11C,BCHE,DST,JAZF1,C1QC,SGCE,CACNA1G,RAB29,LDLRAD4,CA12,CACNA2D1,CALB1,CAMK2D,RUNX1T1,ARHGEF25,LDB2,CDK11B,SEPT7,LONRF2,DCLK1,EVI5L,CDO1,DLGAP1,CCPG1,CRLF1,NUMBL,JAM2,MYL6B,ARHGEF6,ABI3BP,MYRIP,ZNF521,CNRIP1,SLC35F1,FAM171B,CREM,ENTPD4,CREB5,ANKRD44,CLIP3,SNCAIP,CSF1,TENM4,CSF2RA,FEZ1,LRRC3B,IPCEF1,VCAN,SOCS5,PLCXD3,PNPLA8,CFAP61,PYGO1,BOC,HDAC9,ARHGAP24,TOX,ZFYVE16,DGKB,BRINP1,ZNF804A,SNAP91,NTM,RABGAP1L,CCDC3,DMD,DNM1,SHANK1,ABCC9,EBF1,EDN3,EDNRA,SEMA3D,TMTC1,EGFR,SORBS3,CERCAM,RGS17,ELN,EML1,CALCRL,EMX2,LRRC17,EPHB1,EPS8,DENND4A,TLR7,KATNAL1,HSPA12B,NRN1,WAC,FABP7,CORO2B,EFEMP1,FCGRT,MED12L,FGF12,FGFR1,FHL1,SCARA3,FLNC,SGIP1,AFF2,COQ5,TMEM175,WDR83,SMC2,USP21,NPTN,GPR153,FUT9,TPPP3,TMEM151A,DKK3,GABRA1,IQGAP2,GAP43,ACSS1,GATM,GFRA2,FREM1,PCDH17,CSDC2,GHR,LYVE1,HPGDS,GLRB,LOXL3,GNAO1,LNX1,GPM6A,GPM6B,GPR19,GRK4,GRIA4,GRIK1,NR3C1,PRDM5,GRM7,GSN,LINGO1,ADAMTS6,GUCY1A1,SLC2A6,IRAK3,RASSF8,HAS2,INSYN1,SYNPO,CFAP126,NEGR1,SMAP1,IGF1,LRRCC1,IL6ST,IL11RA,BRINP3,DIPK1A,LRRTM3,KCNA6,KCNC1,KCNJ16,STXBP5,LAMA2,LAMP2,LMO2,SYTL4,VWA5A,HECTD2,LSAMP,SMAD9,MAP2,MATN2,MEF2C,MITF,MMP16,MN1,SAMD5,CCDC80,ADAM22,NRBP2,MYBPC1,MYH7,MYO7A,NBL1,NCAM1,NDUFA5,NEFM,NELL1,NFIA,NFIX,CNOT4,NPY,NPR2,NTRK2,DDR2,NUCB2,PCSK5,PDE1A,PDE3A,PDE4D,PDGFRA,ENPP2,PENK,CDK14,SEMA5B,PIK3R1,TMEM38A,GPSM2,PLCL1,FXYD1,PLP1,PCDH18,PURG,PMP22,PRRX1,SDK2,SLC36A4,FAT3,PPP3CC,NKAIN4,EPDR1,PROX1,MASP1,SYTL2,CNTLN,MTMR10,PTH1R,PXK,PTN,TMEM260,PTPRD,PTPRE,PTPRZ1,PTX3,PYGM,FAT4,FAM184A,ARID4A,BEND5,PRRT2,MORC4,RGS10,RNASEL,DCUN1D2,SETD5,ROBO1,ROBO2,RIMKLA,TCP11L1,MEG3,KCNIP3,CCDC112,SEMA6D,SCN2B,LRRTM4,PRCD,FNIP1,ELMOD1,ZFP2,MRAS,ZFP30,PPP1R9A,SH3GL3,FERMT1,DOCK10,NTNG1,CHD9,FHOD3,NLGN1,DZIP1,SLC1A3,FAM81A,PREX2,BTBD3,SLC8A1,ARHGEF40,CCDC88A,TET1,SLIT1,GKAP1,SMARCD3,RCOR3,RIMS1,MBD5,PALLD,PDZRN3,SCN3B,DOP1A,TNIK,ZCCHC24,SOX15,CLUAP1,GLT8D1,SPP1,RAP1GAP2,CLSTN2,COLGALT2,SST,EPB41L3,NKAIN2,INKA2,RGL1,SULF2,ARHGEF9,C3orf70,ANKRD12,TAL1,FAM208A,ADGRL3,AGTPBP1,KLHL4,EHBP1,TCF4,PSD3,TNS2,TEK,ZFPM2,ITGB3BP,GALNT17,TIE1,ASXL3,TLR4,DAAM2,TNNT1,NPL,TPM2,SYNPO2,PRMT8,LRRC24,TRPS1,SSBP2,RFTN2,TST,TMEFF2,SGK3,SLAIN1,FLRT2,PLEKHH2,VSNL1,WNT7A,ZNF23,KCNT2,REEP1,UPF3A,SLC30A4,PMEPA1,LRP8,EVI5,ADAMTS9,NAV3,PPP1R3F,PLSCR4,FAM13C,SMIM8,CERS6,RNF170,MSRB3,ADAMTS10,SSPN,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K1 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 2.55E-25 1.30E-21 6.64E-24 6.05E-23 112 255 "PTCHD1,LTBP4,GPRASP2,LRRC4C,SEMA4G,MADD,RGS20,ASTN1,CACNA1A,CACNB2,HAP1,CDC25B,LONRF2,KIAA1549L,NRXN1,NRXN2,CNTFR,CREB5,CSF2RA,FEZ1,ATRNL1,ST18,TOX,DNAL1,RUSC2,SV2A,SRGAP3,ARNT2,DMD,SHANK1,MAMLD1,CACNG7,TMEM35A,EPHA5,APC2,CHST15,FOXG1,NRG3,SRRM4,FAXC,GFRA1,PPARGC1A,LOXL3,PCLO,GRIK2,CACFD1,MFSD2A,FRMD5,NEGR1,CELF5,ATCAY,IGSF1,LRRTM1,KCNH2,L1CAM,LSAMP,LSS,MAP2,MEIS2,MXI1,NCAM2,NELL2,NFIA,NUCB2,GPR137C,PAK3,PAX6,PCDH9,GDAP1L1,ZFYVE21,TMEM38A,POU6F1,EPDR1,MDGA2,GAL3ST4,PRRT2,ATXN1,LRRTM4,SCG5,NTNG1,NLGN1,SLC1A3,FAM214B,SORCS3,SNAP25,DOP1A,SOX2,GLT8D1,NPAS3,CLSTN2,ZSCAN29,SEPT3,RHBDL3,ANKRD12,SEMA4A,CUX2,AZIN2,PSD3,NACC2,DDHD1,NR2E1,PRMT8,TUBB2A,FLRT1,MGAT5B,PLPPR2,CCDC136,WNT7A,NPDC1,ZNF23,FMN2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 2.78E-25 1.42E-21 7.19E-24 6.55E-23 89 178 "TTYH1,NDRG2,ADCY2,ADCYAP1R1,SPARCL1,ALCAM,ATP1A2,ADGRB1,BMP7,CA12,PRC1,CDO1,ADGRG1,JAM2,CLU,IGDCC3,TENM4,NCAN,CST3,SDC3,RASSF2,DBI,LYPD1,NTM,OLIG1,DPP6,EDNRB,EFNB3,EGFR,TNK2,OLIG2,ETV1,ADGRV1,FABP7,C1orf61,PDLIM5,TPPP3,DKK3,DNER,GFAP,PCDH17,LUZP2,DCLK2,GPM6B,HAS2,SCRG1,CFAP126,HES5,LIX1,FGFBP3,NRBP2,MT3,SCG3,RSPO2,MXI1,NFIA,NFIX,NTRK2,ENPP2,SERPINE2,PLP1,PMP2,SCHIP1,FAT3,NKAIN4,PTN,PTPRO,PTPRZ1,RFX4,RIT2,KLHDC8A,S100B,BCAN,SLC1A2,SLC1A3,ITPRID2,SMOC1,INKA2,SULF2,MLC1,WWC1,WSCD1,ZEB1,TCF12,PSD3,HEY1,CABIN1,SEZ6L,LRP8" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.01E-25 1.53E-21 7.75E-24 7.06E-23 156 419 "TTYH1,ABR,SLITRK1,ADD1,GRAMD1B,OGT,C6orf89,TMEM263,ASCL1,ATP2B2,ZNF583,KIF1A,CFLAR,SYNJ1,DIRAS1,KALRN,HAP1,CAMK2D,SCARB1,CDC25B,DCLK1,ARHGAP33,ADGRG1,SRSF11,SLIT2,NRXN2,COL4A5,ACBD5,SLC35F1,CRMP1,ABCG1,NCAN,CNTNAP2,SLITRK5,RIMS2,ST18,TCAF1,SCRN1,DCC,HP1BP3,SRGAP3,RAB39B,MED12,SLC12A6,SNX29,FSD1L,SORBS3,ELAVL3,EML1,STARD3NL,OLIG2,ANKRD13B,APC2,ADGRV1,EZH1,CLVS1,FABP7,ZIC4,SPSB4,FGF13,MAD2L2,FOXG1,ANKFY1,NSG2,GAD1,SRRM4,PCDH11X,DCLK2,GPM6A,GPM6B,STMN2,GRIK2,RNF165,ZBTB49,MFSD2A,GUCY1A2,RNFT2,CELF3,TOX2,FRMD5,DDX19B,IGFBPL1,ATCAY,ZIC5,HES5,KCNH2,KLC1,LRRC4B,MAP2,MBP,CHIC1,SHC3,SCAMP5,TAGLN3,MYT1,NELL2,NRCAM,GDAP1L1,LRP12,PKIA,MAPK10,PROX1,GDPD1,RAD51D,CARF,GSTCD,CCDC25,SGSM1,ATAT1,RTN1,RXRA,LINC00461,HES6,ZNF821,HSPA4L,SCG5,CCDC92,WDR37,PEX26,SIRT2,KBTBD4,ARFGAP1,ZNF667,MAST1,SNAP25,KIF13A,SOX2,SOX11,TEX2,NPAS3,CAMTA2,MAPK8IP3,TTBK2,SYT11,FGD4,DDHD2,CAMTA1,ACSL6,CUX2,FRYL,AHCYL2,SIK3,UCHL1,MGAT5B,ZFP37,ZIC1,ZIC3,DPYSL5,STMN4,STOX2,LMAN2L,WNK2,PARP11,FZD3,NHSL1,SPATA13" Coexpression Atlas ratio_SC_vs_MESO_1000_K5 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 4.81E-25 2.45E-21 1.23E-23 1.12E-22 186 541 "TTYH1,SYN3,CSMD2,TMEM132B,ADCYAP1R1,UNC5A,SYT13,DOC2A,LRCH2,PPFIA2,CNIH2,VAT1L,PPP4R4,CARMIL3,CACNA1A,SYT6,VSTM2A,CLDN10,DCLK1,CHGA,CHRNA4,RAB3C,CHRNB2,NRXN1,NRXN2,ANKRD35,IGDCC3,HS3ST5,CRMP1,C1QL2,LRRC3B,RIMS4,FAM131B,SEC14L5,ECE2,HDAC9,KATNAL2,TOX,PHYHIP,BRINP1,JAKMIP2,TMEM130,PARD6A,NTM,RABGAP1L,CHRDL1,HS3ST2,FAM57B,DPYSL2,EDIL3,ST8SIA3,ATL1,CACNG7,AASS,LINC00599,ELAVL2,SEZ6,EPHB1,ANKRD13B,ETV1,PIPOX,CEND1,FABP7,TUBB4A,PPP1R1B,ZNF589,OLFM1,ACTL6B,MAD2L2,HPCAL4,FLT1,SYT3,CSPG5,NSG1,HHIPL1,JPH4,SRRM4,IGSF5,RUNDC3A,TTBK1,GLDC,TOX3,GNAO1,GNG3,GNG4,LPAR4,MCHR1,PCLO,GRIA4,GRM3,LINGO1,WIF1,IGSF21,C1orf94,FRMD5,HRH3,ARHGAP36,LRRC75A,ATCAY,BTBD17,SHISAL1,KNDC1,IGSF1,LRRTM3,OLFM3,KCND2,KCNN2,KCNN3,KCNQ2,KIF5A,CAMK2N2,FGFBP3,C2orf80,SCAMP5,WDR49,CPNE9,SCG3,FXYD7,NAP1L2,NAP1L3,NEFM,NELL2,NOS1,NPTX2,ZDHHC22,PAH,PAK3,GDAP1L1,CAMKV,PLP1,PCDH18,EPB41L4B,POU3F4,PPP2R2B,GDPD2,PTN,PTPRN,PTPRZ1,TMEM145,ZMAT4,RGS7,RIT2,RORB,RIMKLA,STX1B,RYR1,DRAXIN,PPM1E,BCAN,NLGN1,LRRC55,IGSF9B,SNCB,SOX1,TRERF1,SOX2,SOX3,NMNAT2,LHFPL4,UNC5B,LMO3,STAC2,RHBDL3,ARHGEF9,ARC,SYP,SYT1,ACSL6,TMEM151B,SLC19A3,PCDHAC2,RNF175,CHST8,FBXL16,ENHO,RELL2,TLL2,ANKRD24,MGAT5B,VGF,VSNL1,TSPAN11,RBFOX3,DPYSL5,TMEM63C,NETO1" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.32E-25 3.22E-21 1.61E-23 1.47E-22 233 741 "ABAT,FMNL2,ADCY2,AXIN2,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,LTBP4,KCNT1,OGT,LRCH2,LCORL,GPAM,APOC1,LRRC4C,SHTN1,LGR5,CDC14B,PPP4R4,IGDCC4,PDE8B,CAPRIN2,NUMB,INSYN2B,SLC4A4,ATP2B3,BCHE,SGCE,CACNA1G,WASF1,MYRF,CACNA1D,CACNA2D1,CACNB2,CALB1,ARHGEF25,LDB2,SLC16A4,REPS2,DCLK1,LGI1,MAGI1,ADGRG1,CHRM4,SLIT2,CLU,NMT2,CNTFR,AKAP7,AKAP5,ZNF521,TENM4,ATRNL1,VCAN,PLXNA4,PHF14,CTH,BOC,DOCK4,DAPK1,DBT,ARMCX2,ZEB2,MAGI2,SRGAP3,RABGAP1L,DNM1,CDON,DOCK2,DRP2,TSPAN5,EDNRA,RASGRP1,SEMA3D,KLHL5,EGFR,MRO,PLXNC1,EMX2,LRRC17,DENND4A,NRN1,FAM198B,FABP7,KIAA1109,FGF11,CAP2,IP6K2,FLNC,AFF2,NOP56,NSG1,ZMAT1,GABRA4,GABRB1,TRAF3IP2,GATM,SESN1,GFRA2,FREM1,CSDC2,GHR,GLI2,PCDH11X,ADGRA3,GPM6B,GPR37,GRIK3,GUCY1A2,GUCY1A1,GUCY1B1,HMGB1,HPSE2,TCEAL6,IGF1,NKD1,PLD5,SLC35G1,KCND2,KLHL23,LAMP2,SYTL4,MAP2,MATN2,MEIS1,KITLG,MOV10,SESN3,CCDC80,MTR,LAYN,MYO9A,NEXMIF,NCAM1,NELL1,NFIA,NFIX,NNAT,NME4,NPR2,PCDH9,PDE1A,PDE3A,PDGFRA,ENPP2,CDK14,PIK3R1,FXYD1,PCDH18,PRRX1,FAT3,TATDN3,PPP2R5C,PPP3CC,PRKACB,PRKCB,MAPK9,LAMA1,GDPD2,CNTLN,PTN,PTPN13,PTPRD,PTPRO,TMEM255A,FAT4,REV3L,RNASEL,ZFHX4,TMEM206,LGR4,MEG3,HUNK,ZNF354C,SEMA6D,SATB1,SCN2A,PRCD,TNFRSF19,STUM,RASA3,ZFP30,ST8SIA1,DZIP1,SLC4A3,PKNOX2,SCMH1,ATF7IP,PALLD,PDZD2,TNIK,SOX5,KDM3A,UHRF1BP1L,PEG10,TSPYL2,NPAS3,LHPP,SMOC1,ST5,SULF2,ADAMTS17,ADGRL3,TCF12,SZT2,PSD3,OBSL1,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,KAT6B,TNNT1,TPM1,TRPS1,FNDC5,DCBLD1,TST,AMOT,FLRT2,PLEKHH2,VSNL1,ZNF711,ZNF23,LYPD6,WNK1,NAV2,WNK3,SSPN,FRMD6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 9.08E-25 4.63E-21 2.31E-23 2.10E-22 61 97 "NCKAP5,EPB41L5,APLP1,ASCL1,KIF1A,ADGRB3,HAP1,CDH2,CDH8,LHX2,NRXN2,QKI,SLC35F1,CNTNAP2,ERC2,CTNND2,RIMS2,ST18,SRGAP3,ELAVL2,B3GAT1,PHYHIPL,PPARGC1A,GLDC,GNAO1,GPM6A,GPM6B,TDRKH,PCLO,STMN2,SOX21,TUBB2B,LSAMP,SCG3,MYT1,NELL2,NOVA1,PAK3,SLC25A23,FAT3,POU3F4,PROX1,GDPD1,PTPRZ1,RTN1,LINC00461,ZFP2,SOX6,HSPA4L,SCG5,KIF21A,ARX,FHOD3,SNAP25,SOX2,NR2E1,FAM181B,WNT7A,ZFP41,REEP1,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.32E-24 6.73E-21 3.33E-23 3.04E-22 136 347 "KIDINS220,ZNF608,OGT,ANK2,ANK3,APLP1,NAE1,GPC2,CALB1,THSD7A,KALRN,INA,UBE2L6,SULT4A1,AKAP6,MAGED1,IGDCC3,CRMP1,CNTNAP2,GREB1,CTNND2,TCAF1,RIMS3,SCRN1,DCC,DCTN1,FAM57B,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,BSCL2,STARD3NL,ENO2,EPB41,NCALD,NRN1,ACSL4,TUBB3,UBE2E3,IP6K2,PCYOX1,JKAMP,UFM1,GPR153,NSG1,DLL3,GAP43,SRRM4,DNER,GFRA1,OS9,GNG3,STMN2,GYG1,CELF3,ACOT7,IGFBPL1,ATCAY,INSM1,KIF5C,KLC1,L1CAM,MAP4,MAP6,MEIS2,SCAMP5,CD200,BLOC1S2,SCG3,TAGLN3,MDGA1,MYO5A,NCAM1,NEFM,NHLH1,NNAT,PAK3,PCMT1,PCSK1,PRTG,PDPK1,GNG2,GDAP1L1,PKM,SCHIP1,NECAB2,POU3F2,MAPK8,NDUFS7,PSMD13,RALGDS,ARID4A,RGS10,ZFHX4,ROBO1,ROBO2,RTN1,SARS,SEMA6D,SCN3A,TNFRSF19,SCG5,SHMT2,RUFY2,SLC6A8,SNCA,KIF21B,SOX11,NMNAT2,BEX1,NFASC,CLASP2,GSE1,SYT1,SYT4,TAC1,CNTN2,ZEB1,FRYL,FAM200B,RBFOX2,FNDC5,SSBP2,UCHL1,ZIC1,ZIC2,NDRG4,TCEAL7,STMN4,SCG2,CIAPIN1,PCBP4,SLC17A6,FAM219B" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Top 40 GSE76381_iPSMoleculeCountsPMLog2 2.52E-24 1.28E-20 6.33E-23 5.77E-22 62 101 "PTCHD1,SEMA6A,ALCAM,SYT13,ANK3,SMIM29,RUNX1T1,CBLN1,INA,TOX,KIAA0513,DBN1,SNAP91,CPEB2,SEZ6L2,PLEKHA1,ELAVL3,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,FYN,DKK3,JPH4,GAP43,STMN2,PTPRT,CELF3,UBE2QL1,NEGR1,CELF5,CD200,HS6ST3,BEX5,NOVA1,PCDH9,PCSK1,TMOD2,FAT3,RIT2,KIAA0895L,RTN1,SCN2A,NLGN1,NAPB,CXXC4,SNAP25,SCN3B,FAM219A,KIF21B,PEG10,EPB41L3,SEPT3,SYP,SYT4,DNAJC12,MTCH1,VGF,TCEAL7,CELF4,SCG2" Coexpression Atlas PCBC_EB_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500 PCBC 2.84E-24 1.45E-20 7.10E-23 6.47E-22 174 499 "AGT,SORCS2,SPARCL1,ASCL1,CACNA1G,MYRF,CABP7,CAMK2A,BRSK2,CBLN1,LGI1,NOG,CHGA,LHX2,IGLON5,CNR1,COL9A1,AKAP5,IGDCC3,ATRNL1,NCAN,RIMS4,PHACTR3,CNTNAP2,RIMS3,DCC,SNAP91,DUSP9,USH1C,EDN3,LINC00599,ELAVL2,ELAVL3,ELAVL4,ADGRV1,NRN1,FABP7,TMEM132C,ZIC4,ACTL6B,C1orf61,FOXF2,NSG2,DACH2,CSPG5,B3GAT1,TMEM151A,PHYHIPL,ILDR2,GAP43,SRRM4,CPLX2,DNER,GFRA1,GFRA2,FREM1,PCSK1N,GNG3,GPM6A,CCDC184,STMN2,GRIA1,GRIA2,C1QL4,GRIA4,GRIK1,GRM8,GUCY1A1,CELF3,WIF1,UBE2QL1,NXPH2,SCRG1,IGFBPL1,CELF5,BTBD17,C2orf72,IGF1,NKD1,HES5,LIX1,SCRT2,INSM1,ITIH2,CDH20,KCNQ2,KIF5C,LRRC4B,CLEC18A,C1orf194,MAP6,MAPT,SCG3,TAGLN3,MTTP,RSPO2,MYBPC1,MYH6,MYL3,MYT1,NCAM1,NEFM,NELL1,NELL2,NHLH1,NNAT,NTRK2,NTRK3,OLR1,KCNK10,PCDH8,PDGFRA,PENK,GDAP1L1,HMGCLL1,PDZRN4,PRRX1,NECAB2,MAGEL2,POU3F2,POU3F4,PPP2R2B,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,RFX4,ZFHX4,HUNK,KCNIP1,RTN1,RXRG,LINC00461,TMEM200C,LRRC55,SLIT1,SLN,SNAP25,CABCOCO1,SOX1,SOX3,SOX10,ENKUR,CLSTN2,SST,SSTR2,SYT4,SYT5,TAC1,TAC3,CNTN2,TF,ASXL3,RIMBP2,SEZ6L,FNDC5,AMOT,FAM181B,ZIC1,ZIC3,KCNT2,CFAP52,CRB2,DPYSL5,SHD,STMN4,SCG2,SLC17A6,FAM181A,PRRT4" Coexpression Atlas adrenal gland adrenal gland Human Protein Atlas 4.27E-24 2.18E-20 1.06E-22 9.67E-22 108 248 "VWA5B2,AS3MT,FAM43B,GALNT13,GRAMD1B,UNC5A,NR0B1,DPP10,MAGEE2,VAT1L,ARSF,CADPS,BRINP2,ASTN1,ATP2B3,BAIAP3,CACNA1B,CABP7,NGB,VSTM2A,RGN,SCARB1,CDH18,CBARP,CHGB,RAB3C,NGEF,IGLON5,WHRN,C2CD2,CALY,PLCXD3,RIMS2,TMEM130,DLX1,CALN1,FAM135B,CELSR3,GPR61,ELAVL4,ADGRV1,TUBB4A,FGF11,FGF12,ADGRA1,GALR1,DNER,CSDC2,LUZP2,KCNMB4,PRLHR,GPR22,RAPGEF4,GRIK1,TMEM179,CELF3,ARHGAP36,TCEAL6,INSM1,KCNA4,KCNJ5,KCNK2,KCNK3,KCNN2,L1CAM,CAMK2N2,MYO7A,PABPC1L2A,MYT1,NPY,NPTX2,PCSK2,PIRT,SLC10A4,PENK,ABCB1,TMIE,ST8SIA5,SEPT4,NXPH1,LRRN3,MAPK4,PRPH,STK32A,NKAIN1,VEPH1,RGS7,TMEM200C,PPM1E,UNC80,PEG10,MCF2L2,ZFR2,FNDC9,ARC,SYT4,KLHL4,ANO4,RALYL,CDH22,RUNDC3B,DNAJC12,FLRT1,NDRG4,FSTL5,SCG2,PCDH15,TMEM63C" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 5.13E-24 2.62E-20 1.27E-22 1.16E-21 103 231 "DPF1,CPNE2,SYN3,NCKAP5,KLHL32,KIAA1211,EPB41L5,APLP1,PHYHD1,ASTN1,CCDC181,KIF1A,ADGRB3,PROM1,MAP7,LONRF2,CDH2,CDH8,JAM2,LHX2,KIAA1549L,NRXN2,QKI,FAM169A,ERC2,CTNND2,RIMS2,RAB39B,DMD,MAMLD1,PLXNC1,ELAVL2,ELAVL4,EMX2,RTN3,ACSL4,FGF12,FGFR3,FHL1,FUT9,B3GAT1,PHYHIPL,GABRB3,ILDR2,KIAA1841,GLDC,DBF4,MAP7D2,GNAO1,GNG3,TDRKH,PCLO,RFFL,RABL2A,SOX21,DDX19B,USP51,INSM1,TUBB2B,LRRTM1,KTN1,LSAMP,PPM1L,SCG3,NEFM,NOVA1,NTRK2,PAK3,PAX6,SEMA5B,SLC25A23,FAT3,GDPD1,SLC22A23,MDGA2,ELOVL2,EML5,PTPRZ1,FBXW7,RTN1,ZFP2,SOX6,KIF21A,PPM1E,ARX,FHOD3,NLGN1,ANKRD6,WDR47,GKAP1,SOX2,NPAS3,LMO3,VPS13A,SYN1,CCDC173,NR2E1,CADM1,SLAIN1,WNT7A,ZFP41,FMN2,REEP1" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000 FaceBase_RNAseq 5.22E-24 2.66E-20 1.29E-22 1.17E-21 283 975 "EMILIN3,ACTN2,NDRG2,PLEKHG5,ADCY2,USP31,PTCHD1,HECW2,ARHGAP20,MARCH4,LTBP4,GPRASP2,AMPD2,APOC1,LRRC4C,CPNE5,LGR5,CDK10,SEMA4G,MADD,IGDCC4,ZFYVE28,RGS20,ASTN1,ATP1A3,ADGRB2,BARD1,C1QC,CACNA1G,GPC2,LDLRAD4,CA12,CACNA1A,CACNA2D1,CACNB2,HAP1,MAP7,REPS2,CDC25B,LONRF2,KCNAB3,CDH18,CDO1,CRLF1,KIAA1549L,NRXN1,NRXN2,MYL6B,CNTFR,PCYT1B,LETMD1,COL9A3,CREB5,CRYBB1,ANKRD44,CLIP3,SNCAIP,CSF1R,CSF2RA,FEZ1,ATRNL1,ST18,TOX,DGKG,SPOCK2,DNAL1,C8orf34,RUSC2,SV2A,SRGAP3,RABGAP1L,CCDC3,ARNT2,DLG2,DMD,SHANK1,ACOT8,MAMLD1,SEMA3D,CACNG7,EGFR,MBNL2,ELAVL4,ELN,TMEM35A,LRRC17,EPHA5,APC2,CHST15,FCGRT,FDFT1,TESK2,FGF11,BAIAP2,FOXG1,ZMYND15,SGIP1,NBEA,TRIM16,NPTN,TMEM151A,NRG3,ABLIM2,FYB1,GAD2,JPH4,ARPP21,HIGD1B,TMEM8B,SRRM4,FAXC,GFRA1,GFRA2,PCDH17,PPARGC1A,ZNF276,RAB30,PCDH11X,STARD3,LOXL3,GRK4,PCLO,RAPGEF4,GRIK2,CACFD1,NR3C1,GSN,TMEM25,MFSD2A,WIF1,FRMD5,HLF,HPSE2,SYNPO,NEGR1,TCEAL6,CELF5,ATCAY,IGF1,IGSF1,IL11RA,ZNF385B,LRRTM1,KCNA6,KCNH2,KHK,L1CAM,LAMA2,VWA5A,LSAMP,LSS,SMAD9,MAP2,MEIS2,SRSF12,KITLG,MOBP,CD200,CPNE9,SAMD5,CCDC80,N6AMT1,HS6ST3,MXI1,MYH3,NEXMIF,TCEAL5,NCAM2,NELL2,NFIA,NFIX,NPY,NUCB2,GPR137C,PAK3,CNTN3,PAX6,PCDH9,PDE1A,PDE3A,PDE4D,PENK,PFKFB2,GDAP1L1,SERPINE2,ZFYVE21,TMEM38A,PLCL1,NXPH1,POU6F1,TATDN3,EPDR1,DIRAS2,PRODH,MASP1,MDGA2,TMEM231,ACSS3,RALGDS,RAP1GAP,GAL3ST4,ZMAT4,PRRT2,MORC4,ZFHX4,MYH14,TMEM100,EMID1,LGR4,DGLUCY,ATXN1,LRRTM4,SCG5,SH3GL2,FERMT1,DOCK10,NTNG1,CNKSR2,NLGN1,DZIP1,SLC1A2,SLC1A3,FAM214B,SORCS3,SNAP25,DOP1A,SOX2,TNIK,GLT8D1,UNC5B,ARHGAP26,CDK19,NPAS3,C11orf87,CLSTN2,NKAIN2,ZSCAN29,SEPT3,ZFR2,RHBDL3,ARHGEF9,PLCB1,ANKRD12,KAZN,SEMA4A,ADGRL3,TCF4,CUX2,AZIN2,PHF24,FAM189A1,PSD3,HIF3A,LEFTY2,SLC44A1,NACC2,DDHD1,NR2E1,ANKRD24,PRMT8,STXBP4,KCNE5,RFTN2,TUBB2A,UCHL1,FLRT1,MGAT5B,PLPPR2,CCDC136,TSPAN11,WNT7A,NPDC1,ZNF23,FMN2,PMEPA1,CADM2,LRP8,PCDH15,NAV3,TMEM163,CERS6,PRRT4,SENP7" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.47E-24 3.81E-20 1.83E-22 1.67E-21 247 815 "ARID1A,RNF157,ADD1,PNMA8B,PWWP2A,INTS2,NR0B1,TAOK1,ARHGAP20,LCORL,PKP4,CADPS,ASCL1,RNF182,DOCK11,BACH1,ADGRB3,FUBP1,SGCE,BTRC,CALB1,RUNX1T1,CBLN1,CDH2,CDH10,DCLK1,ZNF445,SRSF11,CHGB,SOCS6,CHM,SLIT2,PLAA,NMT2,COL9A1,AKAP5,FAM171B,RBM39,CRMP1,HAPLN1,TENM4,CSNK1E,DZIP3,PUM1,ST18,KIAA0408,DOCK4,FGFR1OP2,GAPVD1,TCAF1,KIAA0586,AIF1L,DCT,JAKMIP2,ZNF804A,ZEB2,CEP170,ZC3H11A,GSDME,ALKBH8,G3BP2,DRP2,EBF1,EDIL3,EDNRA,EDNRB,EIF4G1,ELAVL2,ELAVL3,ELAVL4,CALCRL,EMX2,EPB41L2,SRRM1,FABP7,TUBB3,SCML2,CHST15,PRMT5,KIAA1109,MEX3B,ANKFY1,DPYSL4,SMC2,APOPT1,NSG2,DACH2,DLL3,FYN,MEGF10,GABRA4,ILDR2,GAP43,MTHFD2,WASF3,DNER,TUBGCP4,SRCAP,BRD8,TOX3,PCDH11X,CBX1,LPAR4,GPR37,STMN2,CACFD1,CIT,KIF3A,FAM19A2,RNF165,MIER3,HMGCR,HES5,INSM1,KIF5C,CHIC1,MEIS1,MEIS2,KITLG,MMP16,SAMD5,MSI1,TAGLN3,MYBPC1,HNRNPM,NAP1L2,NAP1L3,NASP,NEFM,NEUROD1,CNOT4,PAK3,PCDH8,PCDH9,PRTG,PDPK1,SLC10A4,GPR85,GNG2,OLA1,SERPINI1,PKM,RC3H2,PRRX1,PPP2R5E,KANSL1,MAPK8,MAPK10,WBP1L,ELOVL2,PTN,PTPRZ1,PTX3,CEP97,TMEM255A,C1orf54,MSANTD2,RDX,FIGN,RFX3,RGS4,PBRM1,ZFHX4,TMLHE,ROBO1,ROBO2,PCMTD2,MEG3,NCBP3,SATB1,CSRNP3,DRAXIN,LINC00461,FNIP1,SFPQ,TRA2B,ITSN1,ARX,CHD9,WDR37,SLC1A3,PREX2,SLC12A2,NAPB,SCMH1,SPHKAP,TET1,CPEB4,ZKSCAN3,SMARCA4,SNAP25,SNCA,SOX2,SOX5,ZCCHC24,UNC5B,ZC3H13,KIF1B,RBM26,SRPK2,TROVE2,CLSTN2,LARP4,RGL1,GSE1,JMJD6,PRRC2C,SYNE2,SYPL1,KLHL4,CLASP1,AHCYL2,CBX5,ACTR6,ASXL3,R3HDM1,RBFOX2,TPM1,NR2C2,PRMT8,STXBP4,TSC1,SSBP2,CADM1,UBE3A,FLRT2,NSD2,PCDH20,ZFP37,ZIC1,ZIC3,ZNF711,ZNF24,TRIM9,SMARCAD1,ADAMTS9,SNX27,KCNAB1,FIP1L1,PCBP4,SLC17A6,FZD3,JMJD1C,RSPRY1,VANGL2,GAN,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 7.78E-24 3.97E-20 1.90E-22 1.73E-21 60 97 "ADCYAP1R1,VAT1L,CADPS,CCK,INA,CHGB,RAB3C,FAM171B,CRMP1,CLIP3,PLXNA4,ZNF804A,DLG2,EDNRB,ATL1,ELAVL2,ELAVL4,EYA1,FABP7,TUBB3,FGF13,NSG1,GABRB3,GAP43,IGSF5,GFRA2,GNAO1,GNG3,STMN2,CELF3,LIX1,KIF5C,L1CAM,SYTL4,PACRG,SCG3,TAGLN3,NEFM,NELL2,PCBP3,SLC10A4,GDAP1L1,MAPK10,PRPH,EML5,PTPRZ1,RET,RGS4,RTN1,SCG5,SNAP25,SCN3B,SST,SYT11,SYT1,CUX2,TMEFF2,UCHL1,FSTL5,STMN4" Coexpression Atlas PCBC_ECTO_fibroblast_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 8.29E-24 4.23E-20 2.01E-22 1.84E-21 287 996 "TKTL1,TMEM132B,AXIN2,ERMN,GRAMD1B,ZNF608,SORCS2,APLP1,VAT1L,ASTN1,ATP1A2,KIF1A,BMP7,CA4,CABP7,CAMK2A,CLDN10,CCK,CDH8,CDH18,LGI1,IGFN1,SYNPR,LHX2,DLGAP3,SULT4A1,IGLON5,CNTFR,WHRN,COL9A1,COL9A2,COL11A2,GAL3ST1,TCEAL2,TOGARAM2,NRG2,IGDCC3,FAM171B,HAPLN1,TENM4,LRRC3B,ATRNL1,NCAN,CNTNAP2,FAM169A,CMTM5,PLCXD3,GREB1,CTNND2,BOC,RIMS3,DGKG,C8orf34,LYPD1,SNAP91,KIF19,RAB39B,HS3ST4,CDON,FAM57B,DPP6,USH1C,HEYL,RASGRP1,EFNA2,PLXNC1,ELAVL2,ELAVL3,ELAVL4,EMX2,NCALD,CDHR1,TMEM74,ADGRV1,CLVS1,FABP7,TMEM132C,ZIC4,PRAM1,MED12L,SPSB4,C1orf61,ATP13A4,B3GAT1,PHYHIPL,GABRA3,ILDR2,FAM184B,SALL3,IP6K3,GAP43,SYT17,SRRM4,GPR162,ADAM28,RND1,GLDC,TOX3,PCDH11X,AIFM3,KIAA1958,ZNF782,PRUNE2,GPM6A,DIPK1C,GPR19,LPAR4,TMEM121B,CECR2,STMN2,GRIA1,GRIA4,GRM3,PTPN5,ZBTB49,SOX21,GUCY1B1,CELF3,UBE2QL1,IGSF21,NXPH3,ARHGAP36,MIER3,HAPLN2,IGFBPL1,HPCA,ZDHHC15,USP51,CELF5,ATCAY,IRF8,BTBD17,PLD5,USP54,IGSF1,HES5,LIX1,INSM1,ZNF385B,ITGA7,KCNA1,OLFM3,CDH20,KCND1,KCND2,KCNJ4,KCNQ2,KIF5C,LRRC4B,LMO1,CLEC18A,MAP2,MAP6,KCTD6,SESN3,MSI1,BCO1,SCG3,TAGLN3,DDX25,CTNNA3,MYO7A,TCEAL5,NELL2,NHLH1,NPY,IGSF11,KCNK10,PAX6,PCDH8,PRTG,ENPP2,PGAM2,NLGN3,PLP1,HMGCLL1,SDK2,NECAB2,MAGEL2,FAT3,POU3F2,NKAIN4,VSTM2L,RAB39A,MAPK10,SMIM10L2B,LAMA1,GDPD2,MDGA2,ELOVL2,STK32A,PTPRD,STRC,TMEM255A,FEZF2,KHDRBS2,PRRT2,FIGN,RFX4,RLBP1,ZFHX4,KLHDC8A,EMID1,HUNK,FAM182A,SALL1,SLC30A10,TMEM200C,SCG5,ARX,SLITRK3,NLGN1,SLC1A6,PKNOX2,LRRC55,SLC8A2,SLCO1A2,SLIT1,DMRTC1,RIMS1,SOX1,SOX2,SOX3,SOX5,SOX10,SOX11,SOX15,LHFPL4,SPTB,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SST,SOX21-AS1,ZFR2,SYT1,COBL,SYT4,TAC1,MCF2L,UNC5D,CNTN2,ADGRL3,VWA3A,PHF24,PCDHB15,FAM189A1,PCDHA6,PCDHA3,PCDHA2,THBS4,NR2E1,RIMBP2,TNNT1,PRMT8,TRH,KCNE5,CA14,ANO5,TTPA,CLEC2L,FRRS1L,VGF,RBFOX3,KCNK12,ZIC1,ZIC2,ZIC3,KCNT2,EMX2OS,CRB2,MKRN3,ZBTB16,DPYSL5,LAMP5,CA10,CADM2,GAL3ST3,KCNAB1,FZD3,DOCK8,FAM182B,ST8SIA2,SLC4A10,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 9.55E-24 4.87E-20 2.31E-22 2.10E-21 61 100 "TTYH1,SLITRK1,PCDH19,ASCL1,HAP1,INA,ADGRG1,SRSF11,JAM2,LHX2,NRXN3,IGDCC3,CNTNAP2,CTNND2,RIMS2,ST18,SCRN1,JAKMIP2,ELAVL3,EMX2,OLIG2,ADGRV1,FABP7,FOXG1,PHYHIPL,ILDR2,SRRM4,GLDC,MAP7D2,GNG3,GPM6A,CECR2,STMN2,RNF165,SOX21,USP51,HES5,SHC3,SCG3,MYT1,NRCAM,PAK3,PAX6,SEMA5B,ELOVL2,EML5,PTPRZ1,STRC,FEZF2,SALL1,LINC00461,SOX6,HSPA4L,KIF21A,ARX,SOX2,ACSBG1,SYN1,NR2E1,WNT7A,ZIC1" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.81E-24 5.01E-20 2.36E-22 2.15E-21 55 84 "CSMD3,VAT1L,CADPS,KIF1A,NRP2,INA,DCLK1,CHGB,RAB33A,FAM171B,CRMP1,FEZ1,PLXNA4,NRSN1,SCRN1,ELAVL2,ELAVL4,EYA1,FABP7,TUBB3,FGF13,TPPP3,GAP43,SYT17,IGSF5,GFRA1,GNAO1,STMN2,LIX1,L1CAM,SYTL4,SCG3,NCAM1,NEFM,NELL2,NTRK3,SLC10A4,SERPINE2,MAPK10,EML5,RET,RTN1,FAM19A1,SCG5,SNAP25,SCN3B,EPB41L3,SEPT3,SYT11,SYP,SYT1,ASTN2,CUX2,CADM1,STMN4" Coexpression Atlas PCBC_SC_blastocyst_1000 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.79E-23 9.13E-20 4.28E-22 3.91E-21 286 996 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY5,GALNT13,ADD2,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DPP10,VAT1L,PPP4R4,RASL11B,ASTN1,ATP1A2,ATP1A3,KIF1A,CARMIL3,ADGRB1,LDHD,SYT6,BRSK2,MAP7,CBS,CLDN10,CCK,SYNGR3,CDH8,L3MBTL4,DLGAP1,CACNA2D2,CHGA,SYNPR,RAB3C,CHRNB2,DLGAP3,SLC24A2,FAM19A5,IGLON5,CNTN1,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,GDA,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,SEC14L5,KATNAL2,RIPOR2,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,ST8SIA3,AASS,LINC00599,ELAVL2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,ACTL6B,C1orf61,SYT3,CSPG5,B3GAT1,ABLIM2,PHYHIPL,MEGF11,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,SALL3,ATP8A2,SRRM4,GFRA2,TTBK1,GLDC,PCDH11X,GNAL,GNG3,GNG4,GPM6A,GPM6B,GPR19,LPAR4,CECR2,STMN2,GRIA4,ADAMTS8,GRM3,PTPN5,SOX21,LINGO1,PSIP1,RNFT2,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,C2orf72,ZIC5,PLD5,IGSF1,RIPPLY2,TUBB2B,ZNF385B,KCND2,KCNN1,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,LMO1,FGFBP3,MATK,SYT9,CHST6,SCAMP5,CPNE9,SCG3,DDX25,FXYD7,RCOR2,NELL2,NOS1,NPTX1,HCN1,NTRK3,ZDHHC22,PAH,NLGN3,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PLP1,NECAB2,EPB41L4B,PACSIN1,FAT3,POU3F4,PPP2R2B,PPP2R2C,NKAIN4,RAB39A,PRKCG,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,SLC25A48,KHDRBS2,ZMAT4,RET,RGS7,PRIMA1,RORB,MRAP2,SGSM1,RIMKLA,SYNDIG1,HUNK,STX1B,RYR1,SALL1,SCN4B,TMEM200C,SCG5,SH3GL2,SH3GL3,PPM1E,CNKSR2,SLC1A6,PREX2,LRRC55,SLC8A2,TMEM132D,SLCO1A2,TET1,IGSF9B,SNCB,SNRPN,SOX2,SOX3,SOX15,NMNAT2,LHFPL4,SSTR2,SOX21-AS1,SEPT3,ACSBG1,FGD4,ABCC8,ZFR2,RHBDL3,NUDT10,SYN1,ARC,SYN2,SYP,SYT1,COBL,SYT4,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,RNF175,TEX15,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,PIK3R5,TPD52,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,DPYSL5,PROCA1,PLPPR5,SLC30A3,CADM2,GAL3ST3,SLC17A7,NETO1,FAM198A,JPH3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.95E-23 1.50E-19 7.03E-22 6.41E-21 51 75 "ADCYAP1R1,VAT1L,CADPS,INA,CHGB,FAM171B,PLXNA4,ZNF804A,DLG2,ELAVL2,ELAVL4,EYA1,FABP7,TUBB3,TUBB4A,GAP43,SYT17,IGSF5,GFRA2,GNAO1,GNG3,STMN2,CELF3,LIX1,KIF5C,L1CAM,SYTL4,SCG3,TAGLN3,NEFM,NELL2,SLC10A4,PENK,GDAP1L1,MAPK10,PROX1,PRPH,EML5,RGS4,RTN1,FAM19A1,SCG5,SNAP25,SCN3B,SST,SYT11,SYT1,CUX2,TMEFF2,UCHL1,STMN4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k1 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.97E-23 1.52E-19 7.05E-22 6.42E-21 59 96 "DPP10,ASCL1,ADAM23,CACNA1B,INA,CDH10,CHGB,RAB33A,NRXN3,CNR1,COL9A1,MYRIP,PLCXD3,JAKMIP2,ZNF804A,GRIN3A,HS3ST4,CALN1,ELAVL2,ELAVL4,TUBB3,CORO2B,ATP8A1,DPYSL4,SYT17,DNER,GFRA2,PCDH11X,GRIA1,INSM1,TUBB2B,KCNQ2,KIF5C,MAP4,MAPT,RSPO2,NCAM2,NDP,NEFM,NNAT,NTRK2,OPRL1,CLDN11,PIRT,GPR85,DUSP26,NALCN,MAPK10,PRPH,PTPRO,RET,RGS4,RTN1,SNAP25,SCN3B,C11orf87,CUX2,TMEFF2,STMN4" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000 FaceBase_RNAseq 4.19E-23 2.14E-19 9.89E-22 9.02E-21 279 969 "TTYH1,EMILIN3,ACTN2,NDRG2,ADCY2,RNF157,PTCHD1,KIAA1324,SRPX,ARHGAP20,LTBP4,GPRASP2,ANK1,PPFIA2,APLP1,MAGEE2,CDK10,ASCL1,NCOA1,ASTN1,ADAM23,BACH1,ADGRB2,ADGRB3,BMPR1B,JAZF1,C1QC,CACNA1G,LDLRAD4,CA4,CA12,CACNA1A,CACNA1B,CACNA2D1,VSTM2A,RUNX1T1,REPS2,LONRF2,KCNAB3,CDH8,EVI5L,CDO1,TBRG4,CRLF1,SRSF11,FOXN3,SLIT2,LHX2,KIAA1549L,NRXN1,CLTB,IGLON5,ARHGEF6,COL9A2,SLC4A8,ABI3BP,IGDCC3,SLC35F1,CREB5,ANKRD44,CRYM,AATK,CSF1,CSF1R,CSF2RA,FEZ1,ERC2,GREB1,HDAC9,TOX,SCRN1,SPOCK2,C8orf34,RUSC2,CCDC3,DLG2,DMD,SHANK1,DRP2,DTNA,MAMLD1,ABCC9,HEYL,SEMA3D,EFNA2,EFNA3,EGFR,RASA4,ELN,TMEM35A,EMX2,ENO2,EPB41L1,LRRC17,EPHA5,EPS8,APC2,F3,DLC1,CHST15,FCGRT,FGF11,FGF12,FOXG1,DPYSL4,TRIM16,TPK1,TPPP3,NRG3,TVP23A,FYB1,JPH4,ARPP21,TMEM8B,ACSS1,GATM,PCDH17,PPARGC1A,ZNF276,GLRB,PCDH11X,GNG4,GPT2,GPM6B,CECR2,GRIK2,NR3C1,GSN,MFSD2A,RABL2A,FAM107A,WIF1,FRMD3,SYNPO,NEGR1,IL11RA,BRINP3,INPP1,KCNN3,CREG2,VWA5A,GPR155,MBNL1,ADAM11,IL17D,MEIS2,SRSF12,CD200,CCDC80,ADAM22,MSR1,NRBP2,TAGLN3,NEXMIF,TCEAL5,NCAM2,NELL1,NELL2,NFIA,NFIX,NNAT,NPR2,CLEC9A,NTRK2,CNTN3,PCDH9,PRTG,PDE1A,PDE4D,NLGN3,SERPINE2,SEMA5B,TMEM38A,PLCL1,FXYD1,TRHDE,SCHIP1,PRRX1,SDK2,EPB41L4B,FAT3,NXPH1,POLR2F,POU6F1,NKAIN4,PRKAR1B,MAPK10,PRODH,MDGA2,CNTLN,PTPRD,RAB3A,ACSS3,IQSEC3,ZCWPW1,ENOX1,ZNF493,FEZF2,BEND5,ZMAT4,PRRT2,ZFHX4,MYH14,BAALC,STK32B,EMID1,LRRK2,MEG3,SOX8,RTN1,STX1B,DGLUCY,SALL1,ATXN1,LRRTM4,MRAS,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A3,SLC6A9,SLC8A1,MAST1,SMARCD3,LIMCH1,PDZRN3,TNIK,NPAS3,CLSTN2,SMOC1,DIP2A,ZFR2,RHBDL3,ADAMTS17,PLCB1,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,UNC5D,ADGRL3,SATB2,CUX2,WASHC4,PHF24,FAM189A1,PSD3,THRA,HEY1,NR2E1,TMOD1,SYNPO2,TRPS1,KCNE5,FLRT1,TSPAN11,ZIC2,FMN2,LYPD6,ZBTB16,LAMP5,PMEPA1,CADM2,LRP8,STMN4,PCDH15,NAV3,TMEM163,PCBP4,WNK2,KLHDC1,DPF3,ST8SIA2,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.17E-23 2.63E-19 1.21E-21 1.11E-20 235 772 "RALGAPA1,EMILIN3,NDRG2,ADARB2,ADCY2,ADCY5,SORCS1,ESYT2,ADRB2,OSBPL6,OSBPL8,SRPX,FAM135A,OGT,APC,PHYHD1,TMEM263,CADPS,ASPH,ATP2B1,ALDH7A1,MYOM1,DST,WASF1,CA8,CACNA2D1,CANX,CFL2,RAB3C,SLIT2,KIAA1549L,NMT2,CNTN1,COL9A1,RTTN,CNRIP1,FAM171B,PREPL,AKAP12,ATRNL1,VCAN,DZIP3,PLCXD3,ZEB2,RABGAP1L,GRIN3A,DMPK,CPEB2,CASP8AP2,EDNRB,KMT5B,EIF5,RGS17,DCTN4,EIF1,ENO2,EPB41L2,EPHA5,ENPP6,NCALD,SPEG,ETV1,RASL12,MRVI1,DLC1,MED12L,KIAA1109,FHL1,SUCO,CAP2,SYNCRIP,SGIP1,EFCAB2,SORBS1,SMC2,PDLIM5,DACH2,GPR153,PNMA2,DKK3,MEGF10,GALC,RAPGEF6,GFRA2,PCDH17,PCDH11X,ZNF638,RAB40B,FERMT2,PRUNE2,GPM6B,GRIA4,ADAMTS8,NR3C1,ATE1,KAT7,BVES,RASSF8,HAS2,ZHX1,HNMT,ZDHHC15,NEGR1,SHISAL1,IGF1,NKD1,RBPJ,IGSF1,KCNB1,KCND3,KCNK2,KCNK3,KCNMA1,KIF2A,LAMA2,LIMS1,HECTD2,NCOA7,MBNL1,IL17D,CHIC1,MEF2C,MEIS1,MEIS2,MKLN1,MMP16,CCDC80,NCAM1,NEK1,NFIA,CNOT4,NPTX2,NTRK2,CLDN11,CNTN3,PCDH9,PDE1C,PDE3A,PDE4D,PDGFRA,ENPP2,GPR85,PENK,TMOD2,PFKP,NALCN,PIK3C2A,SCHIP1,PRRX1,MINDY2,KANSL1,PRKAB2,PKN2,DIRAS2,PSD,ZIK1,PTX3,FAT4,DPF2,REV3L,ZFHX4,LGI2,SYNDIG1,KCNIP3,RYR3,ATXN1,LRFN5,SCN2A,SCN3A,TNFRSF19,TRA2B,SH3BGR,SH3GL2,SH3GL3,NTNG1,BTBD3,SCMH1,SORCS3,RIMS1,FAM126B,TNIK,ZHX3,MYCBP2,KIF1B,NPAS3,LMO3,CLASP2,SMOC1,EPB41L3,STX1A,PRRC2C,ARHGEF9,VPS13A,PLCB1,SYT1,COBL,CAMSAP2,AGTPBP1,MGRN1,EHBP1,VWC2,CUX2,TCF12,WASHC4,SYNE1,FAM189A1,ZFPM2,HHIP,NACC2,ZFP91,ERCC6L2,TMOD1,R3HDM1,TNNT1,RBFOX2,RASD2,TPM2,RGMB,SYNPO2,TRPC3,TRPS1,SSBP2,TMEFF2,MICAL1,VLDLR,RBFOX3,FMN2,MAP3K12,LMAN2L,PARP11,RGS7BP,GOPC,FAM13C,MRPL47,MSRB3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 5.59E-23 2.85E-19 1.31E-21 1.19E-20 130 336 "KIDINS220,ZNF608,ANK2,ANK3,APLP1,GPC2,CALB1,THSD7A,KALRN,INA,CBFA2T2,UBE2L6,AKAP6,MAGED1,IGDCC3,CRMP1,CNTNAP2,CTNND2,TCAF1,RIMS3,SCRN1,DCC,DCTN1,FAM57B,ARRDC4,EBF1,SEZ6L2,ELAVL2,ELAVL3,ELAVL4,ENO2,EPB41,NCALD,NRN1,TUBB3,UBE2E3,IP6K2,PCYOX1,GPR153,NSG1,DLL3,GAP43,MTHFD2,SRRM4,DNER,GLUL,GNG3,STMN2,CELF3,IGFBPL1,ATCAY,INSM1,KIF5C,KLC1,IPO5,L1CAM,MAP4,MAP6,MEIS2,MEST,CD200,MRPL42,THYN1,SCG3,TAGLN3,MDGA1,NCAM1,NEFM,NEUROD1,NHLH1,NNAT,PAK3,PCMT1,PRTG,PDPK1,GNG2,PFKFB4,OLA1,GDAP1L1,CAMKV,PKM,SCHIP1,NECAB2,POU3F2,DRAM2,TATDN3,MAPK8,PTCH1,RALGDS,C1orf54,ARID4A,RGS10,ZFHX4,ROBO1,ROBO2,CCDC25,RTN1,SARS,SCN3A,TNFRSF19,SHMT2,SLC6A8,KIF21B,SOX11,KDM3A,NMNAT2,BEX1,NFASC,CLASP2,GSE1,FGD4,SYT1,SYT4,TAC1,CNTN2,ZEB1,FRYL,RBFOX2,FNDC5,SSBP2,UCHL1,CFAP298,ZIC1,ZIC2,NDRG4,TCEAL7,STMN4,SCG2,PCBP4,SLC17A6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Top 40 GSE76381_iPSMoleculeCountsPMLog2 5.95E-23 3.04E-19 1.39E-21 1.26E-20 76 147 "XKR4,TMEM132B,SLITRK1,TMCC3,PCDH10,SYT13,ANK3,APP,ZSCAN18,ASTN1,CALB1,RUNX1T1,INA,CHGA,CHGB,AKAP6,TENM4,JAKMIP2,EFNB3,TENM1,ELAVL2,ELAVL3,TMEM35A,STARD3NL,EPHA5,CACNG2,ACTL6B,EVL,NSG2,NSG1,FUT9,B3GAT1,FYN,JPH4,GAP43,GFRA1,C1QL1,TOX3,GNAO1,GNG4,GPM6B,STMN2,KIF3A,CELF3,NEGR1,CELF5,HTR2A,LSAMP,KITLG,CD200,HS6ST3,NCAM1,NRCAM,KCNK10,PAK3,PBX1,SNX10,FAT3,PXK,PLEKHB2,BSDC1,RET,ZFHX4,RTN1,SCN2A,SCN3B,PEG10,LMO3,SSTR2,SEPT3,ARHGEF12,VGF,CELF4,CADM2,SCG2,SLC17A6" Coexpression Atlas ratio_EB_vs_SC_2500_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 7.37E-23 3.76E-19 1.71E-21 1.56E-20 307 1102 "ASIC1,NCKAP5,CCDC85A,ADRA1B,PCDH19,KCTD16,SORCS2,ARHGAP20,PCDH10,CCDC146,CNIH2,APLP1,APOC2,LRRC4C,LGR5,TMEM263,ASCL1,DACT3,INSYN2B,ATP6V1G2,TTLL9,TTC9B,ADGRB3,BCHE,BMP7,ST3GAL5,MYRF,CDK5R2,CABP7,CBLN1,CDH2,KCNAB3,CDH10,CDH18,LGI1,CDR1,CBARP,CASC2,SLIT2,LHX2,CNGA3,CNR1,CNTFR,WHRN,COL9A2,CRHBP,HAPLN1,TENM4,PLXNA4,CALY,GPSM1,ST18,PYGO1,BOC,DCC,DCT,RUSC2,LYPD1,SNAP91,SPOCK3,CCDC3,KIF19,DLX1,DNAH9,CDON,SHANK1,CPEB2,DRP2,RCAN1,DUSP9,MAMLD1,EBF1,EDN3,EDNRA,SEMA3D,MBNL2,TMEM132E,ELAVL3,CERCAM,ELAVL4,ELN,EMX2,EN2,EPHA5,EPS8,ERBB4,NCALD,APC2,CLVS1,FAM198B,TMEM132C,ZIC4,ZMYND10,ACTL6B,FOXF2,PSD2,SGIP1,AK8,NSG2,DACH2,ST6GALNAC3,ADGRA1,TMEM151A,PHYHIPL,ILDR2,NKX6-2,TMEM8B,CPLX2,DNER,GFRA1,GFRA2,FREM1,PCDH17,GHR,KIRREL3,GJB1,GLRB,PCSK1N,DCLK2,GPM6A,CCDC184,GPER1,STMN2,GRIA1,GRIA2,C1QL4,GRID1,GRIK1,GRIK2,ADAMTS6,CELF3,HAS2,BACH2,SCRG1,HPSE2,HMX1,ZNF491,CFAP126,NEGR1,C2orf72,C5orf24,NKD1,HES5,LIX1,IL6ST,SCRT2,SLC6A17,INSM1,LRRTM1,NME9,ITIH2,KCNA2,CDH20,LRRC4B,LSAMP,SMAD9,CLEC18A,C1orf194,MAP6,AQP11,LRP1B,MEIS2,MN1,SAMD5,CCDC80,TAGLN3,MTTP,RSPO2,MDGA1,LAYN,RTL5,MYT1,NELL1,NEUROD1,NFIX,NHLH1,NPY,NTRK2,DDR2,OLR1,OMG,GPR137C,KCNK10,PALM,CNTN3,PAX6,PCDH8,PRTG,PDE1A,PDGFRA,ENPP2,PENK,HMGCLL1,PDZRN4,PRRX1,SDK2,POU3F2,TMEM235,LRRN3,NKAIN4,MAPK10,PRPH,MASP1,PSD,ELOVL2,PTPRH,PTPRN2,PTPRO,PTX3,TMEM255A,FAT4,ENOX1,RFX4,RGS4,ZFHX4,KLHDC8A,ROBO2,RPE65,FAM161B,WLS,RTN1,FAM182A,AMER2,LRFN5,SCN3A,LINC00461,TNFRSF19,SOX6,NTNG1,MAGI3,ST8SIA1,SLC1A2,PKNOX2,TRIM67,EFHD1,SLIT1,CXXC4,SORCS3,DMRTC1,SNAP25,CABCOCO1,ANKFN1,SCN3B,MYT1L,SOX5,ZCCHC24,SOX10,ENKUR,NPAS3,CLSTN2,SST,SSPO,RGL1,SYT4,SYT5,CNTN2,TBX15,VWA3A,ZEB1,PCDHGB6,AZIN2,TF,DNAH7,ZFPM2,CRB1,TGFBR3,ARL10,ASXL3,DAAM2,RIMBP2,SEZ6L,CDK20,DOK6,TRH,PPIL6,RFTN2,TTC3,TMEFF2,CADM1,AMOT,FLRT1,FAM181B,ZIC1,CFAP52,ELFN1,FMN2,EMX2OS,PLPP4,CRB2,MKRN3,CELF4,DPYSL5,SLC30A4,STMN4,ADAMTS9,SCG2,NAV3,LINC00632,PCBP4,SLC17A6,DNAH10,FAM13C,SLC39A12,FRMD6,CBLN2,FAM181A,PRRT4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.47E-23 4.32E-19 1.96E-21 1.78E-20 139 372 "ASPHD1,CSMD3,NDRG2,MTUS1,LRRC7,ANK2,VAT1L,SLC7A14,CADPS,KIF1A,ADGRB3,NRP2,C1QC,CACNA1B,CACNA1E,INA,LONRF2,DCLK1,CHGB,RAB3C,RAB33A,NRXN1,FAM171B,CRMP1,FEZ1,VCAN,PLXNA4,NRSN1,SCRN1,BRINP1,DCC,SNAP91,SPOCK3,DLG2,GRIN3A,ABCC9,EBF1,EDNRA,EDNRB,ATL1,FRY,EGFR,ELAVL2,ELAVL4,LRRC17,DENND4A,EYA1,FABP7,TUBB3,TUBB4A,EFEMP1,ATP8A1,FDFT1,FGF13,NSG2,NSG1,TPPP3,GABRB3,GAP43,SYT17,IGSF5,GFRA1,GFRA2,FREM1,RAB30,GNAO1,GNG3,STMN2,GRIA2,GSTM5,CELF3,HPSE2,IGF1,DISP2,LIX1,TUBB2B,KIF5A,KIF5C,L1CAM,SYTL4,LSAMP,MATN2,MEIS1,MMP16,SCG3,TAGLN3,MYT1,NCAM1,NEFM,NELL2,NFIX,NNAT,NOVA1,NTRK2,NTRK3,DDR2,PDE3A,PDGFRA,SLC10A4,PENK,TMOD2,PFKP,SERPINE2,FXYD1,PMP22,PRRX1,FAT3,NKAIN4,MAPK10,PRPH,MASP1,EML5,TMEM255A,FAT4,ZMAT4,RET,LGI2,RTN1,SCN2A,SCN3A,FAM19A1,SCG5,SNAP25,SNRPN,SCN3B,SST,SEPT3,SYT11,SYP,SYT1,ASTN2,CUX2,TNNT1,TNR,TMEFF2,CADM1,UCHL1,STMN4,ST7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.35E-22 6.90E-19 3.10E-21 2.82E-20 67 121 "TTYH1,SLITRK1,SHTN1,ASCL1,ATP2B2,CARMIL3,DIRAS1,HAP1,ADGRG1,SRSF11,NRXN3,NRXN2,SLC35F1,NCAN,CNTNAP2,ST18,SCRN1,DLX1,DTNA,EDNRB,ELAVL3,OLIG2,ADGRV1,FABP7,TUBB3,FOXG1,GAD1,GAD2,SRRM4,ACSS1,GPM6A,GPM6B,STMN2,GRIK2,RNF165,MFSD2A,CELF3,TOX2,FRMD5,IGFBPL1,ATCAY,HES5,MAP2,MBP,SHC3,MYT1,NELL2,POU3F4,MAPK10,GDPD1,RTN1,LINC00461,HSPA4L,SCG5,MAST1,SNAP25,LHFPL4,SYT11,FGD4,SYP,MGAT5B,ZIC1,ZIC3,CELF4,DPYSL5,STMN4,FZD3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.35E-22 6.90E-19 3.10E-21 2.82E-20 67 121 "TMCC3,AP2A2,KLHL13,PCDH10,SYT13,ANK3,APP,ZBTB10,CDK5R1,SCAPER,RUNX1T1,INA,ADGRG1,CRHBP,KIAA0408,DCC,SNAP91,NTM,ELAVL2,ELAVL4,EN2,RCAN2,FABP7,FGF13,NSG2,NSG1,FUT9,AP4B1,DKK3,GAP43,GFRA1,GPM6A,STMN2,GRM5,TOX2,NEGR1,SHISA6,SHISAL1,LSAMP,TAGLN3,NCAM1,ZDHHC22,PBX1,PCSK2,GPR173,PDZRN4,POU6F1,RTN1,AMER2,SEMA6D,SCN3A,NAPB,SNCA,SCN3B,MYT1L,KIF21B,PEG10,BEX1,LMO3,CLASP2,DOK6,TUB,TMEFF2,UCHL1,CELF4,REEP1,NETO2" Coexpression Atlas PCBC_ratio_EB_vs_SC_cfr-2X-p05 Embryoid Body Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.21E-22 1.13E-18 5.03E-21 4.59E-20 454 1823 "CPNE2,TTYH1,ABAT,ABR,NDRG2,PLEKHG5,ADCY6,AXIN2,KIAA1211,KIDINS220,AGT,SORCS2,ALAD,SPARCL1,SPOP,SRPX,BCAR3,PCDH10,LTBP4,AMPD2,C6orf89,CNIH2,APAF1,APBA2,APBB1,GAS7,APLP1,SEMA4G,TMEM263,IGDCC4,ARRB1,CCDC74A,DACT3,ZBTB10,ATP2B1,CADM3,ATP6V1G2,BBS2,BCL7A,NRP2,BMP7,ST3GAL5,MTMR3,AP1M1,WASF1,MYRF,BAIAP3,CFAP410,CAMK2D,CAST,SPAG9,RUNX1T1,ARHGEF25,CBLN1,INA,CBFA2T2,CDH2,ARHGAP33,LGI1,CDR1,CCPG1,NOG,CRLF1,CFL2,ADGRG1,CHGB,JAM2,SLIT2,LHX2,KMT2C,IGFBP7-AS1,CLTB,TMEM59L,CNTFR,COL4A5,COL9A2,MAGED1,ZNF521,IGDCC3,CPS1,ENTPD4,HAPLN1,RNF14,CLIP3,SNCAIP,CSF1,TENM4,FEZ2,ATRNL1,CST3,SDC3,CTNND2,GPSM1,BOC,TCAF1,ZFYVE16,ZNF337,CTIF,SIRPA,ZEB2,HP1BP3,RUSC2,LYPD1,RHOBTB1,FAM107B,CCDC3,DMD,DNM1,DMPK,USP3,CD99L2,SLC29A4,CDON,RCAN1,ARRDC4,EDIL3,TSPAN5,EDN1,EDN3,EDNRA,EDNRB,EEF1A2,HIPK3,SEMA3D,KLHL5,SIDT2,EFNA2,SH3GLB1,EFNB3,MBNL2,RASA4,SORBS3,ING4,ELAVL3,CERCAM,ELN,C3orf18,LRRC23,LRRC17,MTSS1L,EPS8,NCALD,EFS,SPEG,RRAGB,NRN1,F3,FAM198B,PTK2B,EFEMP1,CHST15,FCGRT,FGFR3,BAIAP2,AMOTL2,FHL1,SCARA3,MEX3B,CAP2,SEMA6C,EVL,FLNC,FLYWCH1,TMEM175,DPYSL4,PDLIM5,NSG2,ST6GALNAC3,PNMA2,SARAF,TPPP3,DKK3,ILDR2,DENND2A,FAM120B,ZMYND11,GALC,NEK6,GAP43,ERAP1,TMEM8B,STARD10,DNER,GPR162,AHDC1,GFRA1,FREM1,CSDC2,GHR,C1QL1,GLS,PCSK1N,GP1BB,GPM6A,ATF7,CCDC184,STON1,BTN2A1,GSN,RABL2A,GUCY1A1,GUCY1B1,CELF3,HAS2,ZHX1,MAN1B1,ARHGAP19,SCRG1,SYNPO,CFAP126,LINC00667,IFI16,C5orf24,NKD1,LIX1,IL6ST,TMEM240,IL11RA,INSM1,ITGAV,C2CD4C,JAK1,KCNH2,KIFC3,TTYH2,LAMA2,LRRC4B,LAMP2,LIFR,LIMS1,LSAMP,CLEC18A,MAN2A2,MAP2,MATN2,MDFI,MEIS1,MEIS2,MEST,MGAT3,KITLG,MID1,MN1,SESN3,CCDC80,NRBP2,MTR,RSPO2,SAMD14,MXI1,LAYN,RTL5,FXYD6,NCAM1,NEFM,NELL1,ALDH1L2,NHLH1,NTRK2,DDR2,NUCB2,ODF2,OLR1,PALM,PCDHGC3,PRTG,PDGFRA,ENPP2,GPR173,GNG2,PENK,PFKFB3,PFKFB4,SERPINE2,PIK3R1,XRN1,GPSM2,PLCD1,PLEC,PLTP,C11orf49,PMP22,LRP12,PRRX1,SDK2,POU3F2,LRRN3,PPP3CC,NKAIN4,VSTM2L,CEP41,PKIA,PRPH,RELN,PTCH1,BDNF-AS,PTH1R,PXK,PTN,PTPRD,PEX2,RIPOR1,TMEM231,RAB3IL1,PID1,RALGDS,OXR1,BEND5,PRRT2,RFX4,RGS4,ZFHX4,RNH1,KIRREL1,BAALC,KIAA0895L,MELTF-AS1,PLPPR3,HUNK,HSD11B1L,ATAT1,WLS,CLIP1,RTN1,MIR124-2HG,SEMA6D,SATB1,HES6,TNFRSF19,ZNF821,GALNT10,MRAS,ZFP30,CHD9,FNDC3A,CCDC92,ST3GAL3,SEC31A,DZIP1,ANKRD6,SLC4A3,NBPF1,SMTN,WDR47,FAM214B,PKNOX2,SIRT2,SCMH1,EFHD1,SLIT1,SMARCD3,ANKRD36,LIMCH1,LMBRD1,PALLD,PDZRN3,FAM219A,WDTC1,SPATA7,ZCCHC24,SOX11,KDM3A,ZSWIM8,GLT8D1,SPP1,TEX2,PEG10,CDK19,CLSTN2,ITPRID2,SST,EPB41L3,ERBIN,NACAD,MAPK8IP3,APOM,SEPT8,RGL1,DIP2A,SULF2,FAM168A,SYT11,C12orf76,DDHD2,ROBO3,PDLIM2,CNTN2,ADGRL3,IQCE,DMXL2,ZFP90,TCF12,PCDHGC5,PCDHGB6,PCDHGA11,PCDHGA3,PSD3,ARHGEF12,TF,GPR161,TGFBR3,THRA,HEY1,DAAM2,TNS1,TPM1,TPM2,RGMB,TRO,FNDC5,DCBLD1,SSBP2,TTC3,CADM1,FLRT2,FAM181B,PLPPR2,TOM1L2,LMF1,TSPAN11,WIPF1,NPDC1,XRCC4,ZNF711,ELFN1,NDRG4,CRB2,TCEAL7,DPYSL5,MEIS3,PMEPA1,PRDM2,DNALI1,PARP6,STMN4,RNF103,ADAMTS9,TMEM178A,SCG2,SEMA3B,PCBP4,MVB12B,PARP11,GOPC,KAT6A,RNF170,MSRB3,ADAMTS10,SNX14,FRMD6,IFT88,NETO2,ST8SIA2,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.75E-22 1.40E-18 6.21E-21 5.66E-20 85 179 "ABAT,TRMT9B,CADPS,ASCL1,GPC2,THSD7A,PTBP2,VXN,BRSK2,PRC1,CBFA2T2,SEPT7,CDC25B,FOXN3,IGDCC3,ST18,DCC,ZEB2,CEP170,ELAVL2,ELAVL4,EN2,PLEKHO1,EPB41,EFS,ADGRV1,NRN1,CLVS1,TUBB3,ATP8A1,SPSB4,AMOTL2,DLL3,SRRM4,GFRA1,PSRC1,CELF3,IGFBPL1,HSP90AA1,BTBD17,INSM1,KCNQ2,STMN1,AFDN,MSI1,TAGLN3,NAP1L1,RCOR2,NELL1,NEUROD1,NHLH1,NOVA1,NPTX2,PCDH8,PCSK2,SEMA5B,GPSM2,SCHIP1,POU3F2,PROX1,ARID4A,ZMAT4,RGS4,KLHDC8A,FBXW7,RPS20,HES6,TNFRSF19,SFPQ,ANKRD6,SOX2,SOX11,SULF2,SEPT3,GSE1,RHBDL3,TCF12,PSD3,CRB1,FNDC5,TSPAN11,MKRN3,ZNF195,TUBA1A,PCBP4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.75E-22 1.40E-18 6.21E-21 5.66E-20 85 179 "ABAT,TRMT9B,CADPS,ASCL1,GPC2,THSD7A,PTBP2,VXN,BRSK2,PRC1,CBFA2T2,SEPT7,CDC25B,FOXN3,IGDCC3,ST18,DCC,ZEB2,CEP170,ELAVL2,ELAVL4,EN2,PLEKHO1,EPB41,EFS,ADGRV1,NRN1,CLVS1,TUBB3,ATP8A1,SPSB4,AMOTL2,DLL3,SRRM4,GFRA1,PSRC1,CELF3,IGFBPL1,HSP90AA1,BTBD17,INSM1,KCNQ2,STMN1,AFDN,MSI1,TAGLN3,NAP1L1,RCOR2,NELL1,NEUROD1,NHLH1,NOVA1,NPTX2,PCDH8,PCSK2,SEMA5B,GPSM2,SCHIP1,POU3F2,PROX1,ARID4A,ZMAT4,RGS4,KLHDC8A,FBXW7,RPS20,HES6,TNFRSF19,SFPQ,ANKRD6,SOX2,SOX11,SULF2,SEPT3,GSE1,RHBDL3,TCF12,PSD3,CRB1,FNDC5,TSPAN11,MKRN3,ZNF195,TUBA1A,PCBP4" Coexpression Atlas Arv_EB-LF_1000_K4 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 3.00E-22 1.53E-18 6.74E-21 6.14E-20 154 436 "PCDH19,KCTD16,SORCS2,DPP10,LRCH2,CNIH2,LRRC4C,LGR5,RNF182,MYRF,CALB2,CABP7,VSTM2A,LGI1,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,TENM4,ATRNL1,NCAN,CNTNAP2,DCT,LYPD1,SNAP91,SPOCK3,DLX1,DPP6,USH1C,EDIL3,EDN3,SEMA3D,ELAVL3,ELAVL4,EN2,EPHA5,ADGRV1,CLVS1,TMEM132C,ZIC4,ACTL6B,HPCAL4,C1orf61,PSD2,NSG2,DACH2,TMEM151A,PHYHIPL,GABRA2,CHL1,ILDR2,GAD2,ARPP21,GAP43,SRRM4,CPLX2,DNER,GFRA2,FREM1,PCSK1N,GPM6A,CCDC184,STMN2,GRIA2,C1QL4,CELF3,WIF1,NXPH2,BACH2,SCRG1,HPSE2,IGFBPL1,CELF5,C2orf72,LIX1,SCRT2,BRINP3,SLC6A17,INSM1,OLFM3,CDH20,LRRC4B,CLEC18A,RSPO2,NELL1,NNAT,NPY,NTRK2,OLR1,PAX6,PCDH8,PENK,GDAP1L1,HMGCLL1,PDZRN4,SDK2,NECAB2,MAGEL2,POU3F2,NKAIN4,PRPH,PSD,LAMA1,ELOVL2,PTPRN,PTPRO,TMEM255A,RFX4,ZFHX4,HUNK,KCNIP1,RTN1,AMER2,LRFN5,LINC00461,TNFRSF19,TMEM200C,PKNOX2,LRRC55,TRIM67,SLIT1,DMRTC1,SNAP25,ENKUR,CLSTN2,SST,SYT4,SYT5,TAC1,TAC3,CNTN2,ANO4,PCDHGB6,TF,CRB1,ASXL3,RIMBP2,SEZ6L,DOK6,FAM181B,ZIC1,PLPP4,CRB2,DPYSL5,CA10,STMN4,SCG2,SLC17A6,DNAH10,FAM13C,PAK5,SLC4A10" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 3.05E-22 1.56E-18 6.83E-21 6.23E-20 279 981 "ACTN2,ARID1A,ERMN,PTCHD1,SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,CEP126,GAS7,VAT1L,APOC2,LGR5,SPTBN4,ZFYVE28,ARRB2,PDE8B,NCOA1,ATP1A3,ATP2B2,MTMR9,KIF1A,ADAM23,TTLL9,BARD1,NRP2,ZNF599,PROM1,KSR1,SCAPER,JAZF1,IL33,LDLRAD4,CFAP410,CA4,CA12,CACNA1A,CACNA1B,PTBP2,CAMK2A,CAMK2B,CBLN1,INA,CDK11B,REPS2,KCNAB3,CDO1,CRLF1,SRSF11,FOXN3,SLIT2,KIAA1549L,NRXN2,CLU,SLC24A2,CLTB,VAX2,NIPBL,IGLON5,ARHGEF6,CNTFR,IQCK,COL9A2,BAG4,IGDCC3,NECTIN3,CREM,CREB5,HAPLN1,CRYBB1,CLIP3,CRYM,CSF2RA,MICAL2,PLCH2,FAM169A,ERC2,PHF14,GREB1,ST18,SCRN1,JAKMIP2,C8orf34,TIAM2,DLG2,DRP2,MAMLD1,DNM1L,ABCC9,ST8SIA3,SNX29,TMTC1,RASA4,LPAR6,EIF4G2,ELAVL3,ELN,RASGRP2,SEZ6,EPS8,NCALD,CDKL3,PIPOX,ADGRV1,CLVS1,WAC,PTK2B,ZIC4,CORO2B,FGF12,HPCAL4,FOXG1,ZMYND15,SEMA6C,SEMA4D,DLL3,STAU2,FUT9,ADGRA1,ABLIM2,FYB1,GAD1,ARPP21,TMEM8B,C15orf41,SRRM4,ACSS1,KIAA1841,PPARGC1A,LYVE1,NTNG2,GLRB,ZNF638,GNG4,GOLGB1,ADAP1,GRK4,PCLO,GRIA1,GRIK2,GSN,TMEM25,GUCY1B1,CELF3,HPSE2,SYNPO,USP51,SMAP1,ATCAY,ICA1,KNDC1,LRRCC1,IGSF1,SCIN,HES5,LIX1,IL11RA,INSM1,ZNF385B,ITGAV,KCNA6,KLHL23,KIT,KTN1,HECTD2,GPR155,MID1,PPM1L,MITF,MOBP,CPNE9,BCO1,MSR1,SCG3,RSPO2,MYH3,MYO6,MYT1,TCEAL5,NASP,NFIA,NFIX,NPR2,CLEC9A,OPCML,PAK3,ETFRF1,PDE4B,PDE4D,ENPP2,PDPK1,NLGN3,GDAP1L1,SERPINE2,GPSM2,TRHDE,PILRA,FAT3,NXPH1,NKAIN4,PRKAR1B,MAPK10,DIRAS2,MASP1,GDPD2,CNTLN,EML5,STRC,RAB3IL1,PID1,ACSS3,CCDC40,IQSEC3,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,REV3L,FIGN,MYH14,STK32B,KCNIP3,SH3GL2,FERMT1,ASAP3,DOCK10,CCDC92,SLC1A2,SLC1A3,PREX2,SLC6A9,CCDC88A,SLCO1A2,CXXC4,INAVA,LIMCH1,LMBRD1,TNIK,SPATA7,BDP1,SOX11,ARHGAP26,C11orf87,PBLD,SAMSN1,DIP2A,ACSBG1,SYP,TMEM136,ACSL6,SATB2,WASHC4,LEFTY2,THRA,ASXL3,LRRC8A,TMOD1,STXBP4,TRPS1,TUB,FLRT2,RBFOX3,MICU3,ZBTB16,EML6,LAMP5,PMEPA1,CADM2,LRP8,STMN4,PCDH15,TMEM163,CAB39L,DNAH10,CERS6,PRRT4,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.53E-22 1.80E-18 7.87E-21 7.17E-20 247 836 "NCKAP5,GALNT13,SORCS1,ESYT2,HECW2,OSBPL1A,OSBPL8,PCDH10,FAM135A,SYT13,LCORL,APAF1,VAT1L,USP37,MIER1,TMEFF1,CADPS,ASPH,ASTN1,DDX3Y,INSYN2B,RNF182,ADAM23,DST,SCAPER,LDLRAD4,CACNA1B,THSD7A,PTBP2,CH25H,RUNX1T1,CBLN1,MYOM2,CDH2,CDH10,DCLK1,CDO1,CRLF1,RCBTB2,SYNPR,RAB3C,SLIT2,PLAA,CNR1,COL9A1,BTF3L4,ZNF521,ANKRD44,NCOR1,ABCG1,CRYM,LRIG1,CSNK1G3,VCAN,PDE4DIP,ERC2,APPL1,PNPLA8,PYGO1,HDAC9,TOX,PITPNC1,DNAJC6,JAKMIP2,ZEB2,TIAM2,CEP170,MAGI2,BLOC1S6,SPOCK3,NTM,DLX1,DRD1,EBF1,EDNRA,SEMA3D,EFNA3,EGFR,TENM1,CALCRL,EPHA5,EPS8,DENND4A,ETV1,EYA1,TMEM132C,ZIC4,SCML2,DLC1,GORAB,FGF13,UBE2E3,MEX3B,FOXF2,SYNCRIP,SGIP1,NBEA,DACH2,MEGF10,GABRA4,GABRB1,ARPP21,SALL3,SRRM4,DNER,PPARGC1A,GLRB,GLS,TOX3,RAB40B,GNG4,ADGRA3,GPD2,GPR12,LPAR4,GRIA2,GRM7,PSIP1,MAP4K5,WIF1,RASSF8,FRMD3,BACH2,MIER3,NEGR1,IFI16,LRRCC1,LRRTM3,KCNA1,KCNA4,KCNK2,KIF5C,LSAMP,MAP2,RSPO2,MYH3,MYO5A,NAP1L2,NEFM,NFIA,DDR2,PAK3,PCDH8,PDE4D,ENPP2,GPR85,GNG2,NLGN3,NALCN,PCDH18,HMGCLL1,TRHDE,LRP12,PRRX1,ING3,EPB41L4B,FAT3,PPP3CB,MAPK8,GRAMD1C,ZIK1,PTPRE,PTPRZ1,TMEM255A,OXR1,ARID4A,GAL3ST4,ZMAT4,FIGN,KLHL11,ZFHX4,C12orf49,ROBO1,PRR5L,ACER3,RPS20,SALL1,SATB1,CSRNP3,SCN3A,LRRTM4,FAM19A1,FNIP1,TNFRSF19,SFPQ,KIF21A,NTNG1,ANKRD6,WDR37,ZNF365,SLC1A3,CCDC88A,SLC12A2,SLC14A1,SLC15A2,LIMCH1,CMTR2,FAM126B,SON,SOX2,SOX11,HECW1,NPAS3,LMO3,TROVE2,ELOVL4,TTBK2,KLHL7,ARHGEF9,TAC1,UNC5D,ADGRL3,TBX15,TCF4,TRIM2,PCDHB15,PCDHB10,PSD3,PCDHB3,PUM2,ZFP91,ERCC6L2,TMPO,KAT6B,SYNPO2,TRPS1,SSBP2,RPRM,FRRS1L,UGT8,FLRT2,TBC1D15,WIPF1,PCDH20,ZBTB14,ZNF711,FMN2,LRP8,KCNAB1,PARP11,GOPC,FAM13C,PHTF2,ZDHHC20,FRMD6,CBLN2,SOCS4" Coexpression Atlas BM Top 100 - thalamus BM Top 100 - thalamus Body Map 4.58E-22 2.33E-18 1.01E-20 9.21E-20 45 63 "SLC12A5,ERMN,AQP4,CALB1,INA,SYNGR3,DLGAP1,SYNPR,RIMS3,OLIG1,ELAVL2,OLIG2,GABRA1,GABRG2,GAD1,GAP43,CPLX1,GFAP,CNDP1,GPR37,STMN2,GRM1,MAG,MAP4,MOBP,MOG,NEFM,NEFH,OPCML,ANLN,TMEM235,SCN2A,NTNG1,SLC8A1,C11orf87,SYT1,TCF7L2,TF,SLAIN1,CCDC136,P2RY12,ZIC1,TMEM163,SLC17A6,CPNE4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.58E-22 2.34E-18 1.01E-20 9.21E-20 250 851 "NCKAP5,GALNT13,AXIN2,SORCS1,RNF150,ESYT2,HECW2,OSBPL1A,PCDH10,FAM135A,SYT13,ANK2,LCORL,APAF1,VAT1L,CDC14B,MIER1,PLA2G4C,CADPS,ASPH,RASL11B,ASTN1,INSYN2B,DYNLL1,RNF182,ADAM23,BLM,CDK5R1,DST,SCAPER,LDLRAD4,CACNA1B,THSD7A,RUNX1T1,CBLN1,MYOM2,CDH2,DCLK1,LARGE1,CDO1,CLGN,CRLF1,SYNPR,RAB3C,SLIT2,PLAA,CNR1,AKAP7,SLC4A7,ZNF521,SLC35F1,FAM171B,ANKRD44,NCOR1,ABCG1,CRYM,TENM4,VCAN,ERC2,PNPLA8,RIMS2,PYGO1,HDAC9,TOX,CENPL,SCRN1,PITPNC1,DCT,JAKMIP2,TIAM2,MAGI2,BLOC1S6,RHOBTB1,SPOCK3,NTM,RABGAP1L,ARNT2,DLX1,DRD1,EDNRA,ANKRD46,EFNA3,EGFR,TENM1,SRPK3,DMTN,EPHA5,EPS8,DENND4A,EYA1,TBC1D16,TMEM132C,ZIC4,SCML2,DLC1,TESK2,GORAB,SCARA3,UBE2E3,FOXF2,SGIP1,NBEA,DACH2,MEGF10,GABRA1,GABRA4,CHL1,GABRB1,GAD1,FAM120B,SRRM4,DNER,FREM1,PPARGC1A,GLI2,GLRB,TOX3,RAB40B,GNG4,ADGRA3,GPR12,GPR17,LPAR4,GRIA2,GRM3,PSIP1,WIF1,BACH2,SYNPO,NEGR1,CELF5,IFI16,LRRTM3,KCNA4,KCNK2,KIF5C,LSAMP,GPR155,PPM1L,RSPO2,MYH3,MYO5A,NAP1L2,NDP,NEK1,VWA2,DDR2,PAK3,PCDH8,PDE4D,ENPP2,GPR85,GNG2,PFKFB3,NLGN3,PCDH18,HMGCLL1,TRHDE,LRP12,PRRX1,ING3,EPB41L4B,SLC22A23,ZIK1,PTPRE,PEX2,TUG1,TMEM255A,ZNF493,OXR1,ARID4A,GAL3ST4,FIGN,SEC61A2,ZFHX4,C12orf49,ROBO1,PRR5L,ACER3,RPS20,SALL1,SATB1,CSRNP3,SCN3A,LRRTM4,FAM19A1,TNFRSF19,SGK1,PPM1E,FRMPD1,DZIP1,ANKRD6,ZNF365,SLC1A3,YPEL4,CCDC88A,SLC14A1,SLC15A2,ATF7IP,LIMCH1,RIMS1,SON,SOX2,SOX11,KIF1B,NPAS3,TROVE2,CLSTN2,ELOVL4,TTBK2,KLHL7,ZC3H4,SYNE2,ARHGEF9,TAC1,CAMTA1,UNC5D,ADGRL3,TBX15,TCF4,PCDHB15,PCDHB10,PSD3,PCDHB3,PUM2,FBXL16,TIMP4,ASXL3,TMPO,KAT6B,SYNPO2,TRPS1,SSBP2,RPRM,UGT8,TBC1D15,WIPF1,WNT7A,PCDH20,ZBTB14,FMN2,LRP8,KCNAB1,PARP11,FAM13C,PAK5,CERS6,FRMD6,CBLN2,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.80E-22 2.45E-18 1.06E-20 9.62E-20 124 320 "TTYH1,ABAT,NDRG2,ADCYAP1R1,SPARCL1,SEMA6A,PCDH10,CCDC146,LRRC4C,ASCL1,PCDHGB4,ATP1A2,BARD1,CA12,HIP1R,SPAG9,PRC1,SEPT7,CDC25B,CDO1,CDR1,ADGRG1,CLU,TJP2,QKI,AKAP7,COL9A1,CREB5,SNCAIP,LRIG1,NCAN,CST3,SDC3,CTNND2,ARHGAP32,RASSF2,DBI,LYPD1,SV2A,OLIG1,DPP6,DTNA,EDNRB,EGFR,TNK2,OLIG2,LRRC17,ADGRV1,FAM198B,FABP7,FGFR3,C1orf61,PDLIM5,CSPG5,PHYHIPL,GABRG1,ILDR2,GATM,GFAP,HEPN1,DCLK2,GPM6A,GPM6B,HAS2,SCRG1,CFAP126,C2orf72,HES5,LIX1,LIFR,FGFBP3,MT3,NCAM1,NFIA,NFIX,NTRK2,ENPP2,SERPINE2,PLP1,PLXNB1,PMP2,RC3H2,FAT3,LRRN3,NKAIN4,HYDIN,MASP1,PTCH1,SPDL1,PTN,PTPRZ1,TMEM231,ZCWPW1,VEPH1,RFX4,KLHDC8A,WLS,SALL1,BCAN,SLC1A2,SLC1A3,SLC15A2,LIMCH1,SOX2,NPAS3,SMOC1,INKA2,KANK1,SULF2,MLC1,WWC1,VWA3A,WSCD1,TCF4,HEY1,TMPO,CABIN1,SEZ6L,CADM1,USP1,TFIP11,PRDM2,RGMA,STMN4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.90E-22 3.01E-18 1.29E-20 1.18E-19 103 243 "SORCS1,PCDH10,DPP10,TNRC6C,CADPS,ASTN1,ADAM23,CDK5R1,WASF1,LDLRAD4,CACNA1D,THSD7A,RUNX1T1,CDH10,COL9A1,SLC35F1,FAM171B,CRMP1,ANKRD44,SNCAIP,TENM4,FEZ1,SIPA1L1,ERC2,PYGO1,TOX,JAKMIP2,GRIN3A,DNM1,HS3ST4,DRP2,EDNRA,CACNG7,EGFR,EPHA5,EFS,ETV1,EYA1,TMEM132C,CORO2B,FOXF2,SGIP1,DPYSL4,ZBED3,PRELID3A,TVP23A,MEGF10,GABRA1,GFRA2,PCDH17,GLI2,GLRB,B4GALNT4,GRIA2,GRM3,GUCY1A1,MSL1,IFI16,MARK1,MN1,JAKMIP3,RSPO2,SAMD14,MYH3,NDP,NEFM,CLDN11,ZNF827,GPR85,SSH1,PCDH18,TRHDE,PRRX1,PTCH1,PTPRG,FAT4,ZFHX4,ROBO1,SALL1,SCN3A,TNFRSF19,NTNG1,SNAP25,PDZD2,CAND2,NPAS3,EPB41L3,ARHGEF9,MTCL1,CAMTA1,ADGRL3,VWC2,CUX2,FAM189A1,PCDHB7,PCDHB3,HIF3A,TRPS1,RPRM,FLRT2,FMN2,TCEAL7,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K1 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 7.54E-22 3.85E-18 1.64E-20 1.50E-19 117 295 "ABR,ERMN,PLEKHH1,ALCAM,LTBP4,EPB41L5,APLP1,RGS20,ATP2B1,CADM3,PROM1,DST,THSD7A,MAP7,INA,CDH2,FOXN3,CHN2,LHX2,NRXN1,NRXN2,CSF2RA,LRRC3B,CTNND2,HDAC9,MYADM,DGKB,WDR20,SHANK1,CACNG7,EFNA3,ELAVL2,RGS17,EMX2,LRRC23,RRAGB,CEND1,TUBB4A,OLFM1,FGF11,FUT9,PHYHIPL,ILDR2,JPH4,GFRA1,CSDC2,GLDC,TOX3,MAP7D2,CECR2,STMN2,SOX21,LINGO1,PSIP1,HMGCL,CPT1C,TCEAL6,SHISAL1,LRRTM1,CDH20,KCNN3,KHK,MATN2,CD200,CCDC80,ADAM22,NRBP2,NRCAM,PAX6,PDE1A,NLGN3,ZFYVE21,SLC25A23,MAPKAP1,NKAIN4,PXK,EML5,CEP97,FEZF2,TSPY26P,PRRT2,TCP11L1,STK32B,EMID1,FOXRED2,SALL1,MAPK12,LRRTM4,PPP1R9A,NTNG1,FHOD3,CLSTN1,SLC4A3,SMARCA4,PALLD,TRERF1,SOX2,BEX1,LMO3,ADAMTS17,MTCL1,MCF2L,WWC1,WSCD1,WASHC4,BEX4,TNNT1,PRMT8,SLAIN1,FLRT1,CCDC136,ZNF23,CA10,SHD,TMEM163,FZD3,PIANP" Coexpression Atlas ratio_ECTO_vs_SC_2500_K3 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 7.74E-22 3.95E-18 1.68E-20 1.53E-19 250 854 "ABHD6,TKTL1,SORCS2,TRMT9B,APLP1,LGR5,ASCL1,DACT3,DNAJC27-AS1,CA4,CABP7,CAMK2A,CAMK2D,VXN,CCK,P2RX6,CDH2,CDH8,CDH18,LGI1,IGFN1,LHX2,CNTFR,AKAP6,COL4A5,COL9A2,NRG2,HAPLN1,CLIP3,TENM4,GALNT9,CNTNAP2,SLITRK5,CALY,PLCXD3,SLC45A1,GPSM1,ST18,PYGO1,BOC,SPOCK3,CCDC3,KIF19,DMD,CDON,FAM135B,HEYL,EGR3,ELAVL3,ELAVL4,SRPK3,PCOLCE2,C3orf18,EMX2,RAB9B,ERBB4,NCALD,RASL12,CEND1,ECSIT,REEP2,CLVS1,TMEM132C,ZIC4,ZMYND10,ACTL6B,PRKAG2,HPCAL4,CAP2,FLNC,NBEA,RASL10A,NSG2,B3GAT1,TPPP3,PHYHIPL,ILDR2,DENND2A,IP6K3,HIGD1B,TMEM8B,SYT17,MYOZ2,TUBA8,GPR162,CYP46A1,AHDC1,PCDH17,CSDC2,GHR,TOX3,PCDH11X,PCSK1N,RAB40B,DIPK1C,STON1,TMEM121B,STMN2,ADAMTS13,CACFD1,FAM107A,FAM222A,CELF3,MAEL,UBE2QL1,NXPH3,HAPLN2,ZNF491,KIAA1755,HES5,LIX1,TMEM240,INSM1,ZNF385B,LRRTM1,NME9,KCNA1,OLFM3,CDH20,KCNJ4,LRRC4B,LSAMP,SMAD9,CLEC18A,C1orf194,MAP2,MAP6,LRP1B,MEIS2,SESN3,BCO1,TAGLN3,CTNNA3,RSPO2,MDGA1,MYO7A,RTL5,FXYD6,NCAM1,NEUROD1,NHLH1,NPY,IGSF11,KCNK10,PALM,CNTN3,PAX6,PCDH8,PRTG,PDE1C,PDE1B,ENPP2,ST8SIA5,HMGCLL1,ASPDH,PURG,PNMA3,PDZRN4,PMP22,SDK2,PACSIN1,POU3F2,VSTM2L,MAPK4,MAPK10,PRPH,LAMA1,PTH1R,ELOVL2,PTPRD,PTPRH,PTPRO,STRC,TMEM255A,FEZF2,PRRT2,RFX4,RLBP1,ZFHX4,KLHDC8A,HUNK,SOX8,HSD11B1L,KCNIP3,WLS,YJEFN3,KCNIP2,FAM182A,TNFRSF19,SMPD3,SLC30A10,SOX6,ARX,PKNOX2,SLIT1,GKAP1,DMRTC1,RIMS1,SNAP25,FAIM2,UNC80,SOX1,SOX3,SOX5,SOX10,IZUMO4,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SST,SSPO,ADAMTS17,TAC1,ADGRL3,VWA3A,DMXL2,PCDHGB6,SYNE1,PHF24,PCDHB10,CRTC1,PCDHA6,PCDHA3,DICER1-AS1,ASXL3,NR2E1,RIMBP2,DOK6,TRH,PPIL6,FNDC5,RFTN2,TTPA,CLEC2L,FLRT1,TOM1L2,ZIC1,ELFN1,EMX2OS,CRB2,MKRN3,DPYSL5,STMN4,ADAMTS9,DNAH10,FAM182B,SLC4A10,FAM181A" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 8.51E-22 4.34E-18 1.84E-20 1.68E-19 65 118 "TTYH1,ASCL1,CARMIL3,HAP1,CDC25B,ADGRG1,SRSF11,NRXN3,NCAN,CNTNAP2,ST18,SCRN1,DCC,SRGAP3,KBTBD11,DLX1,FSD1L,ELAVL3,OLIG2,EPHB1,APC2,ADGRV1,FABP7,TUBB3,FOXG1,B3GAT1,GAD1,SRRM4,RUNDC3A,DCLK2,GPM6A,GPM6B,STMN2,GRIK2,RNF165,CELF3,FRMD5,HES5,MAP2,SHC3,TAGLN3,MYT1,NELL2,NNAT,PLXNB1,GDPD1,RTN1,LINC00461,SCG5,CXXC4,MAST1,SNAP25,SOX11,LHFPL4,NPAS3,ACSBG1,SYT11,SYP,CUX2,MGAT5B,ZIC3,DPYSL5,STMN4,WNK2,SPATA13" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 8.71E-22 4.44E-18 1.88E-20 1.71E-19 275 969 "EMILIN3,ACTN2,SLC25A25,NDRG2,ADCY2,CCDC85A,RNF157,PTCHD1,KIAA1324,OSBPL8,SRPX,ARHGAP20,LTBP4,GPRASP2,ANK1,PPFIA2,MAGEE2,CDK10,DACT3,NCOA1,ASTN1,ADAM23,ADGRB2,ADGRB3,ZNF599,BMPR1B,JAZF1,C1QC,CACNA1G,LDLRAD4,CACNA1A,CACNA2D1,VSTM2A,RUNX1T1,CBLN1,LRBA,REPS2,LONRF2,KCNAB3,CDH8,EVI5L,CDO1,CRLF1,FOXN3,SLIT2,LHX2,KIAA1549L,NRXN1,CLTB,HOMER3,IGLON5,ARHGEF6,COL9A1,COL9A2,SLC4A7,ABI3BP,IGDCC3,CREB5,HAPLN1,ANKRD44,CRYM,AATK,CSF1R,CSF2RA,FEZ1,ERC2,GREB1,HDAC9,TOX,SCRN1,SPOCK2,RUSC2,CCDC3,DLG2,DLX1,DMD,SHANK1,DRP2,DTNA,DUSP9,MAMLD1,ABCC9,HEYL,SEMA3D,EGFR,RASA4,ELN,TMEM35A,EMX2,ENO2,EPB41L1,LRRC17,EPHA5,EPS8,APC2,ADGRV1,CHST15,FCGRT,FGF11,FGF12,DPYSL4,TRIM16,TPPP3,NRG3,TVP23A,FYB1,JPH4,ARPP21,TMEM8B,ACSS1,PCDH17,PPARGC1A,ZNF276,GLDC,GLRB,PCDH11X,MAP7D2,GPM6B,CECR2,GRIK2,NR3C1,GSN,MFSD2A,FAM107A,WIF1,FRMD3,KLF12,SYNPO,NEGR1,IL11RA,BRINP3,KCNH2,KCNN3,CREG2,VWA5A,GPR155,IL17D,MEIS1,MEIS2,SRSF12,KITLG,MITF,CD200,CCDC80,MSI1,ADAM22,MSR1,NRBP2,TAGLN3,RSPO2,MYCN,NEXMIF,TCEAL5,NCAM2,NELL1,NELL2,NFIA,NFIX,NNAT,NPR2,CLEC9A,NTRK2,CNTN3,PAX6,PCDH9,PRTG,PDE1A,PDE4D,PGAM2,NLGN3,SERPINE2,SEMA5B,TMEM38A,PKM,PLCL1,FXYD1,TRHDE,NECAB2,FAT3,NXPH1,POLR2F,POU3F4,POU6F1,IRX1,NKAIN4,PRKAR1B,MAPK10,PRODH,MDGA2,RAB3A,ACSS3,IQSEC3,ZCWPW1,ENOX1,ZNF493,ZMAT4,PRRT2,FIGN,ZFHX4,MYH14,BAALC,EMID1,LRRK2,MEG3,SOX8,STX1B,DGLUCY,ATXN1,LRRTM4,MRAS,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,NLGN1,SLC1A2,SLC1A3,SLC6A9,SLC8A1,SMARCD3,LIMCH1,PDZRN3,SOX11,ZSWIM8,NPAS3,CLSTN2,DIP2A,ACSBG1,ZFR2,RHBDL3,ADAMTS17,PLCB1,SYP,ASTN2,SEMA4A,MCF2L,TMEM178B,UNC5D,ADGRL3,SATB2,CUX2,WASHC4,PHF24,FAM189A1,PSD3,THRA,SYNPO2,TRPS1,KCNE5,CA14,HSPBP1,FLRT1,TSPAN11,CLIP2,ZIC3,FMN2,LYPD6,ZBTB16,LAMP5,PMEPA1,ZXDA,CADM2,LRP8,STMN4,ADAMTS9,PCDH15,NAV3,TMEM163,PCBP4,WNK2,KLHDC1,DPF3,ST8SIA2,SENP7" Coexpression Atlas PCBC_ratio_SC_vs_PulmonMicrovasc_cfr-2X-p05 Pluripotent Stem Cells_vs_Pulmonary Microvascular-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.23E-21 6.29E-18 2.64E-20 2.41E-19 424 1688 "TTYH1,DGCR6,AS3MT,ARID1A,NDRG2,TMEM132B,ADCY2,RNF157,ADD2,AXIN2,CDC7,PLEKHH1,PWWP2A,NLGN4X,MTA3,ZNF608,OSBPL1A,TBC1D14,WDR35,TXNDC16,SEMA6A,FAM135A,GPRASP2,ZNF687,AMT,MAP4K3,USP28,PHF12,CNIH2,PARG,APLP1,PHYHD1,APOC1,CACHD1,VAT1L,USP37,CDC14B,CASK,TMEFF1,ARHGAP5,CAPRIN2,ZSCAN18,RASL11B,ALDH4A1,ATP1A2,ATP1A3,ATP2B1,ALDH7A1,DPY19L3,ATP6V0A1,KIF1A,BACH1,ADGRB2,BLM,PROM1,NAE1,GYG2,GPC2,DDR1,DIRAS1,PTBP2,SYT6,MAP7,CBR1,CBS,CLDN10,KYAT1,INA,LRBA,CDH2,DCLK1,MAGI1,CDO1,UBE2L6,CACNA2D2,CHN1,PLEKHB1,ZBED5,DNAJB5,IGLON5,PCYT1B,COL9A1,BTF3L4,COL9A3,TCEAL2,BAG4,IGDCC3,NECTIN3,ZNF385A,CRMP1,CLIP3,CRYM,LRIG1,FEZ1,SIPA1L1,VCAN,RIMS4,FAM169A,DZIP3,CTH,FAM131B,ECE2,EARS2,KIF26A,LONRF1,MATR3,RIMS3,TMEM170A,BRINP1,AIF1L,ARMCX2,JAKMIP2,ZBTB24,HEPH,MYEF2,SV2A,RABGAP1L,MTX3,CHRDL1,DLG3,DLG4,DNM1,DMTF1,FAM57B,DTNB,DNAJB6,ABCC5,ABCC9,E2F5,EDIL3,SEZ6L2,EEF1A2,FEM1B,CACNG7,RBM12,EFNB3,KMT5B,AASS,LINC00599,PCOLCE2,BSCL2,PAN3,HSD17B14,EPB41,EPB41L1,ERBB2,EFS,PIPOX,REEP2,FABP7,TBC1D16,TUBB4A,SCML2,PPP1R1B,ZNF589,OLFM1,SPSB4,FGF13,FGFR1,FGFR3,MAD2L2,CAP2,EVL,SEMA4D,FLT1,NBEA,TACC2,SORBS1,SPECC1,FAM49B,NSG1,MPP6,BRSK1,OGA,MEGF10,GABBR1,GABRB3,JPH4,IQGAP2,GAP43,FAXC,GGT7,RND1,GLDC,DBF4,SPIN1,GLI2,CBX1,KDM2B,GNAL,LOXL3,GNG4,GPT2,ADGRA3,GPM6B,B4GALNT4,GPR19,EML4,CECR2,GRIK5,CACFD1,KAT7,MFSD2A,SOX21,LINGO1,PSIP1,MIER3,HMGCR,IGFBPL1,CPT1C,DHX35,ATCAY,ZIC5,RBPJ,LRRCC1,USP54,IGSF1,TUBB2B,ITGA7,KLHL23,KCNK1,KCNN2,KCNQ2,KIF5A,KIF5C,KIT,IPO5,L1CAM,PAXBP1,MSANTD3-TMEFF1,FGFBP3,ARHGAP12,CHST6,MEST,SCAMP5,AFDN,MMP17,CD200,MPP2,SESN3,MSI1,THYN1,SCG3,ZNF92,DDX25,MYCN,MIR4697HG,BEX5,NAP1L2,FXYD6,NAP1L3,NASP,RCOR2,NEFM,NELL2,NME4,NPTX2,ZDHHC22,PBX1,CDK18,GNG2,CDK14,SERPINE2,SEMA5B,CAMKV,PIK3CD,ZNF655,SNX10,PCDH18,PLTP,PLXNB1,CDIP1,PSAT1,EPB41L4B,FSD1,PPM1B,PPP2R2B,KANSL1,PRKAB2,PRKCZ,PRODH,LAMA1,GDPD2,PTN,ZIK1,PTPN13,PTPRD,PTPRG,PTPRZ1,ZSCAN2,NKAIN1,ACSS3,HKR1,PRRT2,ZDHHC4,ARHGEF10L,KIF7,SEC61A2,SLC25A36,NUDT11,RPRD1A,ZNF532,RAVER2,PNMA8A,ROBO1,ELP2,LGR4,PLPPR3,TUNAR,RTKN,ZNF331,CCDC112,RMI1,SALL1,DRAXIN,HES6,SCG5,KIF21A,SH3GL3,ASAP3,AMBRA1,DZIP1,SLC6A8,SLC6A9,SEPHS1,ARHGEF40,ATF7IP,TET1,COA1,OGDHL,INAVA,SNRPN,PDZRN3,TRERF1,SOX2,SOX11,SP4,SPP1,UNC5B,PEG10,ZNF423,BEX1,RAP1GAP2,LHPP,POGZ,ZNF302,ZC4H2,ST5,FCHO1,ZSCAN29,NEK4,SEPT3,GSE1,KLHL7,FGD4,RHBDL3,ARHGEF9,NUDT10,SYT1,COBL,ASTN2,TAC3,MTCL1,PJA1,UNC5D,WWC1,AGTPBP1,ATMIN,TCEA1,WSCD1,TCF7L2,TRIM2,OBSL1,PCDHA6,PCDHA1,SIRT1,THBS4,SLC44A1,GALNT17,ENHO,TMEM9,CBX5,FAM124A,BEX4,KCTD2,PARD3,KAT6B,TNNT1,TP53BP1,TPM2,TRO,CA14,TUB,TUBB2A,CADM1,UCHL1,UGT8,SLAIN1,CCDC136,MICAL1,VLDLR,VSNL1,ZIC2,ZIC3,ZNF711,ZNF708,ZNF24,ZNF28,ZNF74,SPHK2,TCEAL7,ZNF138,ZNF195,ZFAND5,SMARCAD1,MEIS3,RGMA,GAL3ST3,SNX27,ITM2C,ACTR3B,JMJD1C,VANGL2,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.53E-21 7.79E-18 3.26E-20 2.97E-19 42 57 "SYT13,ANK3,VAT1L,RUNX1T1,SEPT7,DCLK1,CHGB,NRXN1,PREPL,ARHGAP32,CEP170,SEZ6L2,ELAVL3,NSG2,NSG1,GAP43,GNG3,GPM6A,CCDC184,PCLO,STMN2,CELF3,CELF5,LSAMP,NCAM1,PAK3,GNG2,TMOD2,PPP2R2B,RALGDS,ZFHX4,RTN1,SNAP25,SCN3B,PEG10,SEPT3,SYT4,TUBB2A,VGF,CELF4,STMN4,SCG2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.90E-21 9.69E-18 4.04E-20 3.68E-19 232 778 "ACTN1,KDM5D,NDRG2,ADCY2,ADCYAP1R1,PNMA8B,GRAMD1B,KLHL13,NR0B1,SORCS2,CC2D2A,C1QTNF3,SPARCL1,ALCAM,ARHGAP20,LTBP4,GPAM,LRRC4C,TMEM263,IGDCC4,DDX3Y,TMEM108,ADAM23,CACNA1G,MYRF,CACNA2D1,CACNB2,ISPD,RUNX1T1,ARHGEF25,CBLN1,LDB2,SCARB1,REPS2,DCLK1,LGI1,SLIT2,CLU,FADS2,CNTFR,AKAP5,ABI3BP,ZNF521,CLIP3,SNCAIP,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,ERC2,PLCXD3,BOC,HDAC9,RIPOR2,ARHGAP24,ARMCX4,ARMCX2,ZEB2,HEPH,SV2A,SRGAP3,DLG4,DNM1,DRP2,ABCC9,E2F6,EDNRA,HEYL,SEMA3D,CACNG7,EGFR,PLXNC1,SORBS3,C8orf37,EMX2,EPB41L2,LRRC17,MTSS1L,EYA1,NRN1,ARMCX1,FAM198B,FABP7,TUBB4A,DLC1,FGF13,MEX3B,FOXM1,FLNC,AFF2,ST6GALNAC3,NSG1,GABRA1,GABRA4,TRAF3IP2,NEK6,IQGAP2,SEPT9,GATM,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,GPM6A,GPM6B,LPAR4,GRIA4,PRDM5,FAM19A2,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,HPSE2,ZDHHC15,TCEAL6,IGF1,NKD1,LIX1,LRRTM3,KCND2,KCND3,KCNJ3,KLHL23,LAMA2,MAP2,MARK1,MATN2,MEF2C,MEIS1,MMP16,LAYN,NEXMIF,NCAM1,ZC3H12B,NFIA,NFIX,NNAT,NME4,DDR2,PAK3,PCDH9,PCSK5,PDE1A,PDE3A,PDGFRA,ANLN,GPSM2,FXYD1,PCDH18,PLTP,PMP22,PRRX1,FAT3,SH3KBP1,LRRN3,RASGEF1B,MASP1,SYTL2,LAMA1,PTCH1,PTH1R,PTN,ZIK1,PTPRD,TMEM255A,ZCWPW1,REV3L,RAVER2,ROBO1,ROBO2,ARMH4,ACER3,LGR4,MEG3,HUNK,ZNF354C,CCDC112,SATB1,FAM19A1,SOX6,RASA3,ARX,NTNG1,SMTN,PKNOX2,LRRC55,SLC8A1,TET1,SORCS3,PALLD,PDZD2,ZCCHC24,PEG10,ZNF423,SPART,SMOC1,ST5,SULF2,ARHGEF9,PJA1,ADGRL3,EHBP1,ZEB1,PSD3,ZFPM2,TGFBR3,HHIP,THRA,ASXL3,HEY2,TNNT1,TNS1,TPM1,TPM2,TRPS1,KCNE5,SSBP2,TMEFF2,PLEKHH2,VSNL1,ZFP37,PMEPA1,STOX2,ADAMTS9,WNK3,NETO2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hNbGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.13E-21 1.09E-17 4.51E-20 4.11E-19 48 72 "KIDINS220,ANK3,ATP2B1,CDK5R1,SCAPER,CACNA1B,RUNX1T1,INA,CDH8,NRXN1,NRXN2,KIAA0408,BRINP1,NTM,EDIL3,ELAVL4,NSG2,GAP43,DNER,PCDH17,GNAO1,PCLO,CNTRL,STMN2,GRIA2,KIF3A,MEIS2,CD200,NCAM1,NNAT,PCDH9,PRKCB,PTPRN2,REV3L,ZFHX4,RTN1,SEMA6D,SCN2A,SCN3A,SLC8A1,SCN3B,MYT1L,MYCBP2,ERC1,SYT1,CELF4,REEP1,TMEM178A" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.12E-21 1.59E-17 6.57E-20 5.99E-19 40 53 "CSMD3,ADCYAP1R1,NME5,VAT1L,SLC7A14,KIF1A,DCLK1,CHGB,FEZ1,PLXNA4,NRSN1,SCRN1,CACNG3,FDFT1,FGF13,NSG2,NSG1,TPPP3,SYT17,IGSF5,STMN2,ARHGAP36,DISP2,LIX1,L1CAM,MAP6,MYT1,NCAM1,NNAT,PMP22,MAPK10,PROX1,RET,RTN1,SCN2A,SNRPN,SYT11,RUNDC3B,DPYSL5,STMN4" Coexpression Atlas Arv_SC-LF_1000_K3 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 3.33E-21 1.70E-17 6.98E-20 6.36E-19 209 679 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY8,GALNT13,UNC5A,NLGN4X,SEMA6A,PDZD4,DPP10,PPP4R4,RASL11B,KIF1A,CARMIL3,SYT6,BRSK2,MAP7,CLDN10,SYNGR3,DLGAP1,CHGA,PLEKHB1,RAB3C,CHRNB2,DLGAP3,FAM189A2,FAM19A5,CCDC151,IGLON5,PCYT1B,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,ERC2,KATNAL2,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SPSB4,ACTL6B,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,SALL3,ATP8A2,GLDC,PCDH11X,GNG3,GNG4,GPM6A,GPM6B,GPR19,LPAR4,CECR2,GRIA4,ADAMTS8,GRM3,PTPN5,LINGO1,RNFT2,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,TUBB2B,KCND2,KCNN1,KCNN2,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,FGFBP3,C2orf80,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,NODAL,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,PLP1,MAGEL2,EPB41L4B,PACSIN1,POU3F4,PPP2R2B,NKAIN4,RAB39A,PRKCG,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RIT2,MRAP2,RIMKLA,RYR1,SALL1,LRRTM4,TMEM200C,SCG5,SH3GL3,SLC1A6,PREX2,SLC8A2,SEPHS1,TMEM132D,SLCO1A2,TET1,SNCB,SNRPN,SOX3,LHFPL4,SOX21-AS1,SEPT3,ZFR2,ARC,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,CCDC173,RNF175,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,PRMT8,CA14,RPRM,VGF,VSNL1,RBFOX3,SLC13A3,KCNK12,ZIC2,ZIC3,KCNT2,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500 Gudmap RNAseq 5.34E-21 2.72E-17 1.12E-19 1.02E-18 388 1522 "DPF1,SERPINA3,ABAT,EMILIN3,METAP1D,NDRG2,ADCY2,RNF157,GRAMD1B,HECW2,PCDH19,NME5,OSBPL6,CC2D2A,C1QTNF1,ADGRF5,SPARCL1,SEMA6A,ALCAM,SRPX,ARHGAP20,LTBP4,PDZD4,SMIM29,PPFIA2,CNIH2,GAS7,DGKZ,VAT1L,TNRC6C,KIAA1614,TMEM263,IGDCC4,MARCH3,RASL11B,ASTN1,ZNF583,CADM3,NOL4,ADAM15,ADGRB2,BBS2,SEC11C,NRP2,LDHD,JAZF1,C1QC,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,ARHGEF25,LDB2,REPS2,LONRF2,DCLK1,EVI5L,CDO1,CRLF1,UBE2L6,NUMBL,CHGB,JAM2,NRXN1,ARHGEF6,PCYT1B,COL9A1,COL9A3,ABI3BP,ZNF521,CNRIP1,FAM171B,ANKRD44,CLIP3,ABCG1,SNCAIP,CSF1,TENM4,CSF3R,FEZ1,LRRC3B,ATRNL1,VCAN,SOCS5,KIAA0040,PLCXD3,DCAF4,PYGO1,CYBB,BOC,HDAC9,ARHGAP24,TOX,ZFYVE16,DGKB,BRINP1,ZNF804A,RABGAP1L,CCDC3,DLG4,DMD,DNM1,SHANK1,EBF1,EDN1,EDN3,EDNRA,HEYL,SEMA3D,TMTC1,EFNA3,EGFR,RASA4,SORBS3,CERCAM,ELN,TMEM35A,EPB41L2,LRRC17,DENND4A,IGSF6,SPEG,TLR7,RASL12,EXTL1,HSPA12B,F8,FABP7,TBC1D16,EFEMP1,FCGRT,GORAB,MED12L,FGF11,SCARA3,ZMYND15,EVL,FLNC,FLT1,SGIP1,AFF2,COQ5,WDR83,NBEA,USP21,KHDRBS3,GPR153,NSG1,FUT9,TPPP3,TMEM151A,NRG3,PHYHIPL,DKK3,GABRA3,HIGD1B,GDF9,GFRA2,FREM1,PCDH17,CSDC2,GHR,PPARGC1A,LYVE1,RUNDC3A,GK,HPGDS,LOXL3,GNAO1,GPM6A,GRK4,GRIA4,PRDM5,GRM7,LINGO1,FAM107A,GUCY1A1,GUCY1B1,SLC2A6,MAP4K5,IRAK3,HAS2,KLF12,INSYN1,HLF,SYNPO,CFAP126,NEGR1,CPT1C,ICA1,IFI16,IGF1,IL6R,IL11RA,BRINP3,DIPK1A,LRRTM3,KCNA6,KCND3,KCNJ16,LAMA2,LRRC4B,STMN1,VWA5A,LSAMP,SMAD9,MAP2,MATN2,MEF2C,MGAT3,MMP16,MN1,CD200,SAMD5,CCDC80,ADAM22,NRBP2,TAGLN3,MX1,MYBPC1,MYO7A,NEXMIF,NCAM1,ZC3H12B,NELL1,NFIA,NFIX,NPY,NPR2,NRGN,DDR2,NUCB2,PAK3,PCSK5,PDE1A,PDGFRA,ENPP2,GPR173,PENK,PFKFB4,CDK14,PGAM2,NLGN3,SERPINE2,ZFYVE21,TMEM38A,PLCB2,PLCL1,FXYD1,PCDH18,PMP22,LRP12,PRRX1,EPB41L4B,SLC36A4,POU6F1,PPP2R2B,PPP3CC,PRKAR1B,MAPK4,EPDR1,MAPK9,MASP1,MDGA2,CNTLN,PTH1R,PTN,PTPRD,PTPRE,PTPRZ1,PTX3,TMEM231,TMEM255A,CCDC40,C1orf54,FAT4,ZCWPW1,BEND5,ZMAT4,PRRT2,RGS4,ROBO2,TCP11L1,LRRK2,MEG3,STX1B,CCDC112,SEMA6D,LRRTM4,FAM19A1,PRCD,TNFRSF19,SOX6,TRIM46,GALNT10,ZFP30,SH3GL3,DOCK10,NTNG1,CNKSR2,NLGN1,ST8SIA1,DZIP1,SLC1A3,FAM81A,LIMS2,RUFY2,SLC6A8,ARHGEF40,CCDC88A,SLIT1,SMARCD3,RIMS1,SNAP25,PALLD,PDZRN3,DOP1A,TNIK,SOX5,ZCCHC24,KIF21B,SPP1,ARHGAP26,ATP10B,CLSTN2,COLGALT2,SST,EPB41L3,NKAIN2,STAC2,SULF2,ARHGEF9,PLCB1,ANKRD12,TAL1,ADGRL3,KLHL4,EHBP1,SATB2,PSD3,TNS2,SIK3,TEK,TF,ZFPM2,SLC44A1,THRA,TIE1,TLR4,DAAM2,KCTD2,TNFRSF1B,KAT6B,PIK3R5,NPL,LRRC24,SSBP2,RFTN2,TUBB2A,TMEFF2,CADM1,FLRT2,PLEKHH2,PLPPR2,CCDC136,MICAL1,VSNL1,WNT7A,PORCN,ZNF711,ZNF32,KCNT2,AGMO,SHD,NAV3,PPP1R3F,PLD4,PLSCR4,FAM13C,CERS6,FAM219B,ADAMTS10,SSPN,FRMD6,NETO2,DPF3,ST8SIA2,SENP7" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_500 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 6.90E-21 3.52E-17 1.44E-19 1.31E-18 166 498 "TTYH1,ADD2,VAT1L,ATP1A2,ATP1A3,LDHD,CA8,SYT6,CLDN10,DCLK1,UBE2L6,CHGA,CHGB,RAB3C,RAB33A,NRXN1,NRXN2,ABCG2,PCYT1B,CABP1,HS3ST5,CP,LRRC3B,GALNT9,RIMS4,FAM131B,SEC14L5,HDAC9,TOX,PHYHIP,JAKMIP2,PARD6A,NTM,AK5,RABGAP1L,CHRDL1,HS3ST2,FAM57B,EDIL3,ATL1,CACNG7,AASS,LINC00599,TMEM35A,LRRC17,RASGRP2,ANKRD13B,ETV1,PIPOX,CEND1,FABP7,PPP1R1B,OLFM1,ACTL6B,HPCAL4,FLT1,NSG1,TMEM151A,GAP43,DNER,GLDC,TOX3,GNAO1,GNG3,GNG4,CCDC184,LPAR4,GRIA4,GRM3,LINGO1,WIF1,C1orf94,HRH3,INSYN1,ATCAY,BTBD17,SHISAL1,IGSF1,LRRTM3,KCND2,KCNMA1,KCNN2,KHK,KIF5A,CAMK2N2,FGFBP3,MAP2,PPM1L,CPNE9,SCG3,MX1,FXYD7,NAP1L2,NEFM,NELL2,NOVA2,NPTX2,NTRK3,ZDHHC22,PAH,PAK3,PCSK1,TMOD2,GDAP1L1,CAMKV,ST8SIA5,FXYD1,PLP1,PCDH18,SCHIP1,PRKCB,KLK6,GDPD2,PTPRN,PTPRN2,PTPRO,PTPRZ1,TMEM145,PYGM,RASGRF2,RGS7,RIT2,RORB,RIMKLA,RYR1,SCN4B,PPM1E,BCAN,NLGN1,LRRC55,SNCB,SOX1,SOX2,SOX3,NMNAT2,LHFPL4,SPP1,LMO3,ACSBG1,ABCC8,RHBDL3,ARHGEF9,ARC,SYP,SYT1,CNTN2,ACSL6,TMEM151B,SLC19A3,PCDHAC2,FBXL16,ENHO,TIMP4,TLL2,ANKRD24,RASD2,TMEFF2,DNAJC12,VGF,VSNL1,LGI4,CRB2,DPYSL5,LAMP5,TMEM163,TMEM63C" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE76381_ESMoleculeCountsPMLog2 8.23E-21 4.20E-17 1.71E-19 1.55E-18 68 131 "ANK3,APLP1,CALB1,THSD7A,KALRN,RUNX1T1,INA,ADGRG1,IGDCC3,DCC,EBF1,SEZ6L2,ELAVL3,EPB41,NRN1,ACSL4,MEX3B,NSG2,NSG1,DLL3,B3GAT1,GAP43,DNER,GFRA1,GNG3,GPM6A,STMN2,IGFBPL1,INSM1,KIF5C,L1CAM,MAP6,MEIS2,SCG3,TAGLN3,NCAM1,NEFM,NEUROD1,NHLH1,PCSK1,PRTG,POU3F2,PKIA,RALGDS,C1orf54,ARID4A,RGS10,ROBO1,RTN1,SCN3A,TNFRSF19,SCG5,SLC6A8,SNCA,BEX1,NFASC,GSE1,SYT4,TAC1,CNTN2,ZEB1,FNDC5,ZIC1,CELF4,STMN4,SCG2,PCBP4,SLC17A6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkF_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.79E-21 4.48E-17 1.82E-19 1.66E-18 43 61 "PCDH10,LRRC4C,ASCL1,PCDHGB4,ADGRB1,HIP1R,INA,SEPT7,NRXN1,NRXN2,CCDC144A,NTM,OLIG1,ELAVL4,EN2,OLIG2,FABP7,TAOK3,C1orf61,NSG2,CSPG5,GAP43,PCDH17,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,KCND2,NCAM1,NOVA1,PCDH9,PDGFRA,PTN,RTN1,SCN2A,SCN3A,BCAN,MYT1L,NPAS3,CELF4,ANKS1B,SLC4A10" Coexpression Atlas Arv_SC-HD_1000_K1 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 2.61E-20 1.33E-16 5.37E-19 4.90E-18 179 559 "SYN3,CSMD2,TMEM132B,ADCY2,GALNT13,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,KIF1A,ADGRB1,HAP1,SYT6,BRSK2,MAP7,CLDN10,CCK,SYNGR3,CHGA,RAB3C,DLGAP3,FAM19A5,CCDC151,IGLON5,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,RIMS4,CNTNAP2,SEC14L5,RIMS3,KCTD8,BRINP1,HS3ST4,FAM57B,DPP6,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,IGSF5,GLDC,PCDH11X,GNG3,GNG4,GPM6B,LPAR4,CECR2,GRIA4,GRIN1,GRM3,LINGO1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,RIPPLY2,TUBB2B,KCND2,KCNN1,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,CHST6,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,NECAB2,MAGEL2,PACSIN1,PPP2R2B,RAB39A,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,HUNK,RYR1,SALL1,TMEM200C,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,TMEM132D,SLCO1A2,IGSF9B,SNCB,SOX3,LHFPL4,SOX21-AS1,SEPT3,ZFR2,ARC,COBL,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,CA14,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,DPYSL5,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Subtype_hGaba_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.92E-20 1.49E-16 5.99E-19 5.46E-18 48 75 "ABR,FMNL2,KIDINS220,ANK3,CDK5R1,BRSK2,RUNX1T1,INA,NRXN1,VCAN,KIAA0408,SCRN1,DCC,NTM,KBTBD11,ELAVL4,STX2,SORBS1,NSG2,OGA,GAP43,DNER,PCDH17,TOX3,PCLO,STMN2,GRIA2,KIF3A,NCAM1,NNAT,REV3L,RTN1,SCN2A,SCN3A,CASC3,SCN3B,MYT1L,SOX11,SYT1,AGTPBP1,CLASP1,PUM2,ZFPM2,UBTF,CELF4,REEP1,RTN4,SPATA13" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.96E-20 1.51E-16 6.05E-19 5.51E-18 233 798 "ABAT,FMNL2,ADCY2,PNMA8B,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,KCNT1,LRCH2,APOC1,CACHD1,LRRC4C,LGR5,CDC14B,PPP4R4,IGDCC4,PDE8B,ZSCAN18,NUMB,INSYN2B,TMEM108,SLC4A4,ATP2B3,RNF182,CACNA1G,WASF1,MYRF,CACNB2,CALB1,KALRN,RUNX1T1,CBLN1,CBFA2T2,REPS2,CDH2,CDH10,DCLK1,MAGI1,CHRM4,SLIT2,CLU,CNTFR,AKAP5,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,BOC,DOCK4,DAPK1,ARMCX2,DCT,MAGI2,RHOBTB1,SV2A,SRGAP3,DNM1,CDON,DRP2,E2F6,TSPAN5,EDNRA,SEMA3D,KLHL5,EGFR,PLXNC1,EMX2,EPB41L1,LRRC17,MTSS1L,NRN1,F3,ABCA8,FAM198B,FABP7,TUBB4A,EFEMP1,OLFM1,MEX3B,CAP2,FLNC,AFF2,ZNF605,ST6GALNAC3,NSG1,GABRA4,GABRB1,TRAF3IP2,NEK6,SEPT9,GATM,GFRA2,FREM1,CSDC2,GHR,GLI2,PCDH11X,GPD2,GPR37,BVES,GUCY1A2,GUCY1A1,TCEAL6,SHISA6,IGF1,NKD1,PLD5,KCND2,KLHL23,SYTL4,MAOB,MAP2,MATN2,MEIS1,KITLG,AFF1,MOV10,SESN3,CCDC80,DDX25,MTR,LAYN,MYO9A,NEXMIF,TCEAL5,NCAM1,ZC3H12B,NEFM,NFIA,NME4,NOS1,NPR2,NUCB2,PCDH9,PDE1A,PDGFRA,CDK14,SERPINI1,PIK3R1,FAM216A,FTO,PCDH18,PRRX1,FAT3,PRKCB,GDPD1,LAMA1,GDPD2,CNTLN,PTN,PTPN13,PTPRG,TMEM255A,FAT4,ZCWPW1,ENOX1,RADX,ZFHX4,ROBO2,TMEM206,ARMH4,LGR4,MEG3,HUNK,KCNIP1,ZNF354C,CCDC112,SEMA6D,PRCD,TNFRSF19,SOX6,STUM,KIF27,RASA3,ZFP30,NTNG1,CNKSR2,ST8SIA1,DZIP1,SLC4A3,PKNOX2,SCMH1,PALLD,TNIK,ZCCHC24,KDM3A,UHRF1BP1L,PEG10,TSPYL2,NPAS3,LHPP,SMOC1,EPB41L3,ZC4H2,ST5,SULF2,ADGRL3,RPGRIP1L,PSD3,OBSL1,TEX15,DNAH7,ZFPM2,ACTR6,ASXL3,DAAM2,BEX4,KAT6B,TNNT1,TPM1,TRPS1,FNDC5,TST,AMOT,UCHL1,PLEKHH2,VSNL1,ZFP37,ZNF711,ZNF23,ELFN1,LYPD6,NAV2,KCNAB1,WNK3,FRMD6,DPF3" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.50E-20 1.78E-16 7.10E-19 6.47E-18 112 288 "C3orf14,ADCY2,OSBPL1A,SORCS2,C1QTNF3,ARHGAP20,SYT13,LRCH2,ANK2,APAF1,TNRC6C,CASK,DPY19L3,DOCK11,IL33,RUNX1T1,LDB2,REPS2,CDH10,SOCS6,ABI3BP,FAM171B,RNF14,NCOR1,LRIG1,SOCS5,BOC,RASSF2,HEPH,CEP170,SRGAP3,NTM,EBF1,EDIL3,EDNRA,SEMA3D,TMTC1,EGFR,PLXNC1,ELAVL2,ARMCX1,ATP8A1,FGF11,NBEA,GAB1,GGTA1P,GHR,GLI2,GLRB,RAB40B,GRIA1,GRIA4,GRM3,RASSF8,UBE2QL1,KLF12,IGF1,KCND2,VWA5A,SMAD1,MAP2,MEIS1,MN1,SESN3,ADAM22,NAP1L3,NDP,NEK1,NFIA,NOVA1,DDR2,PBX1,PCSK5,PDE1A,PDGFRA,PIK3R1,PCDH18,CNTLN,PTPRD,TUG1,FAT4,RBBP6,TMLHE,CCDC112,CSRNP3,LRRTM4,FAM19A1,FNIP1,SCAF8,NTNG1,FNDC3A,ST8SIA1,DZIP1,MAPKBP1,KIF13A,PDZRN3,ZCCHC24,STXBP1,ANKRD12,ADGRL3,KLHL4,ANO4,PCDHB7,PCDHB3,ASXL3,SSBP2,LYPD6,FAM13C,CERS6,SSPN,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500 FaceBase_RNAseq 4.11E-20 2.10E-16 8.32E-19 7.58E-18 162 489 "SLITRK1,ERMN,PTCHD1,KIAA1324,EPB41L5,PHYHD1,SHTN1,CDK10,TMEM108,KIF1A,NRP2,ZNF599,PROM1,CA4,CA12,HAP1,MAP7,CBLN1,INA,CDH2,TBRG4,LHX2,NRXN3,CLCN3,NRXN2,CLU,CRMP1,NCAN,CNTNAP2,FAM169A,SLITRK5,GREB1,RIMS2,AIF1L,JAKMIP2,CHRDL1,DTNA,E2F5,ST8SIA3,ELAVL2,PLEKHA1,EMX2,SEZ6,EPHB1,PIPOX,RRAGB,ADGRV1,REEP2,TUBB3,TUBB4A,FHL1,FOXG1,SEMA4D,SYT3,FUT9,PHYHIPL,GABRB3,ILDR2,JPH4,SALL3,SRRM4,ZNF276,GLDC,TOX3,MAP7D2,GNG3,GPD2,TDRKH,LPAR4,CECR2,STMN2,GRIK2,RNF165,SOX21,CELF3,TOX2,FRMD5,IGFBPL1,USP51,HSP90AA1,ATCAY,ZIC5,HES5,CDH20,KCNK1,IPO5,KTN1,MAOB,AQP11,IL17D,MOBP,MYCN,NAP1L1,NASP,NFIX,NNAT,NOVA1,NRCAM,IGSF11,PAK3,PAX6,PRTG,PDE1A,SNX10,PKM,NECAB2,MAGEL2,POLR2F,MAPK10,GDPD2,ELOVL2,PTPN13,EML5,PTPRZ1,FEZF2,FIGN,RTN1,SALL1,MAPK12,LRRTM4,HSPA4L,SCG5,KIF21A,ARX,CCDC92,SNRPN,SOX2,BEX1,LMO3,PBLD,AJAP1,SYT11,FGD4,MTCL1,ROBO3,MCF2L,TMEM178B,WWC1,WSCD1,ACSL6,TCF7L2,WASHC4,TMEM121,NR2E1,BEX4,PRMT8,KCNE5,CA14,CADM1,SLAIN1,RBFOX3,ZIC2,ZIC3,ZBTB16,DPYSL5,CA10,SLC38A1,PCDH15,TMEM163,FZD3,SPATA13,SENP7" Coexpression Atlas PCBC_ECTO_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_1000 PCBC 6.96E-20 3.55E-16 1.40E-18 1.28E-17 275 997 "SDE2,KCNH8,TKTL1,FAM43B,TMEM132B,UNC5A,OSBPL6,HFM1,C1QTNF4,APLP1,VAT1L,LGR5,ASTN1,ATP1A2,KIF1A,TTLL9,BMP7,CA4,CABP7,CAMK2A,VXN,CLDN10,CCK,LONRF2,CDH8,CDH18,LGI1,IGFN1,SYNPR,LHX2,IGLON5,CNTFR,COL9A1,COL9A2,COL11A2,GAL3ST1,TCEAL2,TOGARAM2,NRG2,IGDCC3,FAM171B,HAPLN1,C1QL2,LRRC3B,NCAN,CNTNAP2,RASGEF1C,CMTM5,UBXN2A,PLCXD3,ARHGEF4,CTNND2,BOC,RIMS3,DGKG,LYPD1,SNAP91,KIF19,CDON,FAM57B,EFNA2,ELAVL2,ELAVL3,ELAVL4,EMX2,NCALD,TMEM74,ADGRV1,CLVS1,FABP7,TMEM132C,ZIC4,PRAM1,MED12L,SPSB4,C1orf61,ATP13A4,KBTBD12,B3GAT1,TVP23A,PHYHIPL,GABRA3,ILDR2,SALL3,IP6K3,SYT17,SRRM4,GPR162,TTBK1,GLDC,TOX3,PCDH11X,AIFM3,DCLK2,ADGRA3,PRUNE2,GPM6A,DIPK1C,LPAR4,CECR2,GRIA1,GRIA4,GRM3,PTPN5,ZBTB49,SOX21,FAM107A,GUCY1B1,TMEM179,CELF3,UBE2QL1,IGSF21,NXPH3,MIER3,HAPLN2,IGFBPL1,C9orf129,SHISA6,CELF5,ATCAY,BTBD17,C2orf72,ZIC5,PLD5,HES5,LIX1,INSM1,TUBB2B,ZNF385B,C2CD4C,KCNA1,OLFM3,KCNQ2,KIF5C,LRRC4B,CLEC18A,MAP6,SYT9,EFHB,WDR49,SESN3,MSI1,BCO1,SCG3,TAGLN3,DDX25,MYO7A,TCEAL5,NELL2,NHLH1,NNAT,NPY,IGSF11,KCNK10,PAX6,PCDH8,PRTG,ENPP2,PGAM2,NLGN3,PLP1,HMGCLL1,ASPDH,SDK2,NECAB2,MAGEL2,FAT3,POU3F2,NKAIN4,VSTM2L,RAB39A,MAPK10,SMIM10L2B,LAMA1,GDPD2,MDGA2,ELOVL2,STK32A,PTPRD,STRC,TMEM255A,FEZF2,KHDRBS2,PRRT2,FIGN,RFX4,PRIMA1,RLBP1,ZFHX4,KLHDC8A,EMID1,HUNK,HSD11B1L,WLS,YJEFN3,FAM182A,SALL1,SLC30A10,TMEM200C,SCG5,ARX,SLITRK3,NLGN1,SLC1A6,PKNOX2,LRRC55,SLC8A2,EFHD1,SLCO1A2,SLIT1,CXXC4,DMRTC1,RIMS1,UNC80,SOX1,SOX3,SOX10,SOX11,SOX15,LHFPL4,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SST,SOX21-AS1,ZFR2,COBL,TAC1,MCF2L,UNC5D,CNTN2,ADGRL3,VWA3A,PHF24,FAM189A1,PCDHA6,PCDHA3,PCDHA2,RNF175,DICER1-AS1,THBS4,ENHO,ASXL3,NR2E1,RIMBP2,FNDC5,KCNE5,CA14,ANO5,TTPA,CLEC2L,FRRS1L,ZNF709,TSPAN11,RBFOX3,ZNF781,LGI4,ZIC1,KCNT2,EMX2OS,CRB2,MKRN3,DPYSL5,LAMP5,PLPPR5,CADM2,STMN4,GAL3ST3,DOCK8,FAM182B,ST8SIA2,FAM181A,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.55E-20 4.36E-16 1.72E-18 1.56E-17 134 377 "AXIN2,SORCS1,PCDH10,SYT13,CACHD1,TNRC6C,CDC14B,MIER1,CADPS,INSYN2B,DYNLL1,RNF182,ADGRB3,LDLRAD4,CACNA1B,THSD7A,CH25H,RUNX1T1,CBLN1,DCLK1,CDO1,CRLF1,CNR1,SLC25A27,ZNF521,SLC35F1,FAM171B,VCAN,ERC2,RIMS2,HDAC9,TOX,SCRN1,BRINP1,PITPNC1,TIAM2,CEP170,MAGI2,NTM,DLX1,GRIN3A,RAB39B,DYNC1I1,EDNRA,SEMA3D,CACNG7,EGFR,TENM1,RGS17,EPHA5,ETV1,EYA1,TMEM132C,SLC9B2,FOXF2,SYNCRIP,SGIP1,NBEA,DACH2,MEGF10,GABRA4,GABRB1,SALL3,FREM1,PCDH17,GLI2,GLRB,GNG4,B4GALNT4,GRIA2,GRM3,WIF1,SYNPO,CELF5,IFI16,LRRTM3,KCNA4,LSAMP,MAP2,MARK1,PPM1L,NDP,DDR2,CNTN3,ENPP2,GPR85,PCDH18,TRHDE,PRRX1,EPB41L4B,TMEM255A,FAT4,OXR1,GAL3ST4,ZFHX4,ROBO1,PRR5L,CCDC112,SALL1,CSRNP3,SCN3A,TNFRSF19,NTNG1,ANKRD6,ZNF365,RADIL,SLC15A2,LIMCH1,TNIK,SOX11,NPAS3,ARHGEF9,TAC1,UNC5D,ADGRL3,TCF4,SATB2,TCF7L2,PCDHB15,HIF3A,ASXL3,HEY2,KAT6B,TRPS1,RFTN2,RPRM,FLRT2,WNT7A,PCDH20,FMN2,LRP8,KCNAB1,FRMD6,SOCS4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 1.03E-19 5.27E-16 2.07E-18 1.88E-17 56 99 "SLITRK1,ASCL1,ATP1A3,HAP1,INA,ADGRG1,SRSF11,LHX2,NRXN3,IGDCC3,NCAN,ST18,SCRN1,DLX1,ELAVL3,OLIG2,ADGRV1,FABP7,ZIC4,TUBB3,FOXG1,ILDR2,GAD1,GAD2,SRRM4,RUNDC3A,GPM6A,GPM6B,STMN2,RNF165,SOX21,CELF3,TOX2,IGFBPL1,ATCAY,HES5,SHC3,SCG3,MYT1,NNAT,NRCAM,POU3F4,LINC00461,HSPA4L,SCG5,KIF21A,ARX,SOX2,ACSBG1,ROBO3,NR2E1,WNT7A,ZIC1,ZIC3,DPYSL5,STMN4" Coexpression Atlas PCBC_EB_fibroblast_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 1.52E-19 7.73E-16 3.02E-18 2.75E-17 163 499 "AGT,SPARCL1,LGR5,ASCL1,CACNA1G,MYRF,CDK5R2,CABP7,CAMK2A,BRSK2,LGI1,NOG,CHGA,LHX2,IGLON5,CNR1,COL9A1,AKAP5,GAL3ST1,IGDCC3,ATRNL1,NCAN,RIMS4,PHACTR3,CNTNAP2,RIMS3,SNAP91,DUSP9,USH1C,EDN3,LINC00599,ELAVL2,ELAVL3,ELAVL4,ADGRV1,NRN1,FABP7,TMEM132C,ZIC4,ACTL6B,HPCAL4,C1orf61,FOXF2,NSG2,DACH2,CSPG5,B3GAT1,TMEM151A,PHYHIPL,ILDR2,SRRM4,CPLX2,DNER,GFRA2,FREM1,RUNDC3A,PCSK1N,GNG3,GPM6A,CCDC184,STMN2,GRIA2,C1QL4,GRIA4,GRIK1,GRM8,GUCY1A1,CELF3,WIF1,UBE2QL1,NXPH2,SCRG1,IGFBPL1,CELF5,BTBD17,C2orf72,IGF1,NKD1,LIX1,SCRT2,INSM1,ITIH2,KCNQ2,LRRC4B,C1orf194,MAP6,MAPT,LRP1B,SCG3,TAGLN3,MTTP,RSPO2,MYH6,MYL3,MYT1,FXYD7,NCAM1,NEFM,NELL1,NHLH1,NPPA,NTRK2,NTRK3,OLR1,KCNK10,PCDH8,PDGFRA,PENK,GDAP1L1,SEMA5B,HMGCLL1,PDZRN4,PRRX1,MAGEL2,POU3F2,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,RFX4,HUNK,KCNIP1,RTN1,RXRG,LINC00461,TMEM200C,LRRC55,SLIT1,SLN,DMRTC1,SNAP25,CABCOCO1,FAIM2,MYT1L,SOX10,ENKUR,CLSTN2,SST,SYT4,SYT5,TAC1,TAC3,CNTN2,TF,ASXL3,SEZ6L,RASD2,FNDC5,FAM181B,ZIC1,ZIC3,CRB2,DPYSL5,SHD,STMN4,SCG2,SLC17A6,FAM181A,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.60E-19 8.18E-16 3.18E-18 2.90E-17 96 233 "ABCF1,KLHL32,PCDH19,EPB41L5,ASTN1,KIF1A,PROM1,BMPR1B,CACNA2D1,PTBP2,CDK11B,CDH2,CDH8,MAGI1,JAM2,KIAA1549L,CNTFR,IQCK,IGDCC3,FAM171B,CREB5,ERC2,CTNND2,RIMS2,KATNAL2,TOX,JAKMIP2,DDX46,RAB39B,DMD,CASP8AP2,MAMLD1,PLXNC1,ACSL4,FGFR3,B3GAT1,ADGRA1,PHYHIPL,ILDR2,KIAA1841,PPARGC1A,DBF4,MAP7D2,GNAO1,GNG3,TDRKH,CIT,SOX21,USP51,INSM1,TUBB2B,KIF5C,KTN1,TM6SF1,MEIS2,SCG3,NASP,NEFM,NOVA1,NTRK2,ODF2,GPR137C,PAK3,PCDH9,SEMA5B,SLC25A23,FAT3,MDGA2,ELOVL2,EML5,PTPRZ1,ENOX1,RFX4,FBXW7,ATXN1,SOX6,ZFP30,KIF21A,PPM1E,ARX,FHOD3,NLGN1,GKAP1,BDP1,NPAS3,SYNE2,SYN1,CCDC173,NR2E1,FAM181B,USP1,WNT7A,ZNF23,FMN2,REEP1,NETO2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K5 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.68E-19 8.55E-16 3.31E-18 3.02E-17 64 124 "NCOA1,ATP2B2,KIF1A,PROM1,JAZF1,CACNA1A,SRSF11,FOXN3,SLIT2,KIAA1549L,NRXN2,IGLON5,ARHGEF6,IQCK,NECTIN3,CREB5,CSF2RA,ERC2,ST18,SCRN1,JAKMIP2,MAMLD1,EIF4G2,ELAVL3,ADGRV1,CLVS1,ZIC4,FOXG1,SEMA6C,FUT9,GAD1,SRRM4,ACSS1,KIAA1841,PPARGC1A,PCLO,GRIK2,CELF3,USP51,ATCAY,IGSF1,HES5,INSM1,KTN1,PPM1L,SCG3,MYT1,NFIA,PAK3,GDAP1L1,FAT3,MAPK10,EML5,SLC1A3,CXXC4,LMBRD1,SOX11,DIP2A,SYP,ACSL6,THRA,TUB,STMN4,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.78E-19 9.10E-16 3.51E-18 3.20E-17 239 836 "ABAT,EMILIN3,ADORA1,USP31,RNF150,ESYT2,ADRB2,OSBPL6,ADGRF5,SRPX,ARHGAP20,FAM135A,AMPH,APAF1,EPB41L5,VAT1L,TNRC6C,ARRB1,RASL11B,BLM,BMP7,FUBP1,C1QC,IL33,LDLRAD4,CA4,CA8,CA12,CACNA2D1,CALB1,THSD7A,ISPD,LDB2,CD86,CD38,CHN2,MS4A7,RAB3C,NRXN3,NMT2,LY86,CNTN1,COL9A1,ZFP28,CLOCK,AKAP12,SNCAIP,CSF1R,VCAN,RIMS2,CX3CR1,CYBB,ARHGAP32,ARHGAP24,SCRN1,AIF1L,SIRPA,ZEB2,ELMO1,MAGI2,CCDC3,RAB39B,DNM2,DTNA,EDNRB,HEYL,PLXNC1,ASB3,EMX2,EPHA5,EPHB1,NCALD,IGSF6,CDHR1,ETV1,TLR7,SIRPB1,EYA1,MRVI1,F8,CORO2B,ATP8A1,FCGR1A,ST3GAL6,MED12L,UBE2E3,SGIP1,FAM49B,DACH2,PNMA2,FYB1,DKK3,MEGF10,GABRA4,ILDR2,SYT17,KIAA1841,IGSF5,GFRA2,FREM1,GGTA1P,LYVE1,BRD8,RAB40B,GRIA4,PARD3B,CACFD1,GRM3,GRM7,PTPRT,GSN,FRMD3,NCKAP1L,SYNPO,HP,NEGR1,IRF8,IFI16,KCNA1,KCNC2,KCND3,KCNK2,LAMA2,LIG4,NCOA7,PIK3AP1,CLEC18A,MAPT,SYT9,CHIC1,TM6SF1,MSR1,MYO5A,MYO6,P2RY13,NCAM1,NCF2,NDP,NELL1,NPTX1,NTRK2,DDR2,OPA1,CLDN11,OXTR,P2RX7,CNTN3,PRTG,PENK,NALCN,RETREG1,SCHIP1,EPDR1,GDPD2,PIGG,PTPRB,PTPRO,PTX3,RIPOR1,FAM184A,RASGRF1,GAL3ST4,DUSP15,TTLL7,LGI2,KIRREL1,PRR5L,EMID1,LGR4,RYR3,SALL1,CSRNP3,LRFN5,SCN7A,SCN8A,SGK1,SH3BGR,SH3GL3,PPM1E,DOCK10,ST8SIA1,ANKRD6,SLA,SLC11A1,EFHD1,CXXC4,CMTR2,FNBP1,SOX11,ZHX3,ARHGAP26,KIF1B,DDN,C11orf87,CLSTN2,SAMSN1,NEK4,PLCB1,TMEM150C,ANKRD28,CAMTA1,TAL1,ANO4,ACSL6,VWC2,SATB2,PCDHB9,PCDHB3,ARHGEF12,ARHGAP9,TEK,TF,HHIP,HEY1,ASXL3,TLR4,ZFP91,TPD52,NPL,RGMB,SYNPO2,TRPC3,TRPS1,SLAIN1,FLRT2,VLDLR,WIPF1,TRIM9,ZFAND5,TMEM178A,PLSCR4,C12orf4,FAM13C,FZD3,CERS6,NETO2,SOCS4,SPATA13,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.03E-19 1.04E-15 3.99E-18 3.64E-17 57 103 "LTBP4,GPRASP2,PPFIA2,ASTN1,VSTM2A,LONRF2,CDH8,LHX2,KIAA1549L,NRXN1,CREB5,FEZ1,TOX,RUSC2,DMD,SHANK1,DTNA,MAMLD1,TMEM35A,EPHA5,APC2,CHST15,DPYSL4,TPPP3,NRG3,PPARGC1A,PCDH11X,MFSD2A,NEGR1,ZIC5,BRINP3,NEXMIF,NCAM2,NELL2,NFIA,PCDH9,PDE1A,SEMA5B,TMEM38A,POU6F1,MDGA2,STX1B,ATXN1,LRRTM4,NTNG1,NLGN1,NPAS3,CLSTN2,RHBDL3,SEMA4A,CUX2,PSD3,KCNE5,ZIC1,FMN2,TMEM163,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.22E-19 1.13E-15 4.34E-18 3.95E-17 235 819 "ASIC2,ADCY2,GALNT13,RNF157,SORCS1,RNF150,PCDH19,C1QTNF3,SEMA6A,ALCAM,SRPX,ABCD2,FAM135A,DPP10,LRCH2,ANK3,APAF1,EPB41L5,TNRC6C,CASK,ASPH,RNF182,DOCK11,OSGIN2,IL33,LDLRAD4,CACNA2D1,THSD7A,CAMK2D,CH25H,RUNX1T1,LDB2,SLC16A4,MYOM2,REPS2,CDC27,CDH2,CDH10,SYNPR,NIPBL,ZNF521,NSL1,AKAP12,NCOR1,LRIG1,SOCS5,APPL1,CTH,PYGO1,BOC,RASSF2,NTM,AK5,MTX3,CCDC3,DNM1,CALN1,ABCC9,EBF1,EDIL3,EDN3,EDNRA,SEMA3D,TMTC1,EFNA3,EGFR,ABI2,PLXNC1,ASB3,ADGRV1,MRVI1,ARMCX1,CORO2B,ATP8A1,SLC9B2,FER,OLFM1,UBE2E3,SYNCRIP,SLC37A3,PDLIM5,PRELID3A,NSG1,GAB1,GABRA1,CHL1,IQGAP2,DNER,FREM1,GGTA1P,GGT5,KIRREL3,BRD8,GLRB,PCDH11X,RAB40B,GPR12,GRIA1,GRIA4,CACFD1,GRM3,PRDM5,GUCY1B1,MAP4K5,WIF1,IRAK3,RASSF8,HAS2,ARHGAP19,KLF12,HNMT,NEGR1,AGFG1,MSL1,IFI16,ITGAV,METTL21A,KCND2,KIF2A,LIG4,VWA5A,LSAMP,CHIC1,MEF2C,MEIS1,MEIS2,MEST,MID1,MMP16,MMP17,MN1,MYO5A,NOVA1,DDR2,PBX1,PCDH8,PDE4B,PDGFRA,GPR85,PENK,ANLN,PIK3R1,PLCL1,PCDH18,LRP12,SH3KBP1,LRRN3,PPP3CA,CEP41,GRAMD1C,RELN,CNTLN,ZIK1,PTPRD,PTX3,FAT4,ARID4A,RBBP6,GAL3ST4,CRTAC1,FIGN,SEC61A2,SLC25A36,LGI2,KIRREL1,PRR5L,LRRK2,LGR4,HUNK,CCDC112,SALL1,CSRNP3,SCN2A,SCN3A,LRRTM4,SCN7A,FAM19A1,SFPQ,TRA2B,DOCK10,NTNG1,ST8SIA1,DZIP1,ANKRD6,WDR37,SLC1A3,SLC8A1,SLC9A5,SLCO1A2,TET1,CXXC4,ZHX3,KIF1B,ITPRID2,NXT2,ELOVL4,NEK4,CEP68,TTBK2,RGL1,KLHL7,RHBDL3,ARHGEF9,ADGRL3,ANO4,ZEB1,PCDHB9,PCDHB3,ZFPM2,ASXL3,TLR4,ZFP91,ERCC6L2,TRO,SSBP2,TTPA,CADM1,AMOT,FLRT2,CCDC14,XPO1,PCDH20,ZBTB14,ZNF24,MKRN3,LYPD6,CELF4,PLSCR4,GOPC,FAM13C,PHTF2,CERS6,NETO2,SOCS4,ST8SIA2" Coexpression Atlas PCBC_SC_CD34+_1000 Progenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_1000 PCBC 2.59E-19 1.32E-15 5.05E-18 4.60E-17 271 987 "SYN3,CSMD2,TMEM132B,ADCY2,ADCY5,ADCY8,GALNT13,ADD2,UNC5A,NLGN4X,SEMA6A,SYT13,PDZD4,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,PROM1,GYG2,CACNA1G,BSN,HAP1,SYT6,BRSK2,MAP7,CLDN10,CCK,MTMR7,SYNGR3,DLGAP1,CACNA2D2,CHGA,RAB3C,CHRNB2,DLGAP3,NRXN1,SLC24A2,FAM189A2,FAM19A5,SULT4A1,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,MYRIP,IGDCC3,HS3ST5,LRRC3B,ATRNL1,CHD5,NCAN,RIMS4,CNTNAP2,FAM169A,PPP1R16B,ERC2,SEC14L5,RIPOR2,KIF26A,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,DGCR5,PLPPR4,CHRDL1,HS3ST4,HS3ST2,CALN1,FAM57B,USH1C,ST8SIA3,SEZ6L2,HEYL,AASS,LINC00599,RASGRP2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,HPCAL4,C1orf61,SYT3,CSPG5,NSG1,B3GAT1,TMEM151A,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,DNER,GFRA2,RND1,GLDC,PCDH11X,LUZP2,PCSK1N,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,ADAMTS8,GRM3,SOX21,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,CELF5,ATCAY,BTBD17,ZIC5,PLD5,IGSF1,RIPPLY2,TUBB2B,KCND2,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,FGFBP3,MATK,CHST6,SCAMP5,CPNE9,ADAM22,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,NODAL,NPTX1,PCBP3,HCN1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,ST8SIA5,JAKMIP1,PNMA3,PSAT1,MAGEL2,EPB41L4B,PACSIN1,FA2H,PPP2R2B,NKAIN4,RAB39A,PRKCG,LAMA1,GDPD2,TMEM145,NKAIN1,RASGRF2,KHDRBS2,ZMAT4,RET,RIT2,RORB,MRAP2,RIMKLA,SYNDIG1,HUNK,RYR1,SALL1,SCN4B,TMEM200C,NLGN4Y,SCG5,SH3GL2,SH3GL3,PPM1E,SLITRK3,CNKSR2,SLC1A6,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,MAST1,IGSF9B,SNCB,SNRPN,SOX2,SOX3,KIF21B,SOX15,NMNAT2,LHFPL4,HECW1,FCHO1,SOX21-AS1,SEPT3,ACSBG1,ABCC8,ZFR2,SYN1,ARC,SYP,SYT1,COBL,SYT4,TAC1,TAC3,TACR1,WWC1,TMEM151B,FAM189A1,SLC19A3,RNF175,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,PIK3R5,TPD52,RASD2,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,SLC30A3,CADM2,GAL3ST3,RGS7BP,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.68E-19 1.37E-15 5.19E-18 4.73E-17 224 770 "AXIN2,SORCS1,USP31,PCDH10,SYT13,OGT,LCORL,APC,CACHD1,TNRC6C,CDC14B,MIER1,CADPS,INSYN2B,DYNLL1,RNF182,ADGRB3,NRP2,BMP7,CDK5R1,DST,LDLRAD4,CACNA1B,CACNA1D,THSD7A,CANX,CH25H,RUNX1T1,CBLN1,RGN,MYOM2,DCLK1,CDO1,CRLF1,FOXN3,RAB3C,CNR1,SLC25A27,ZNF521,SLC35F1,FAM171B,SUSD5,VCAN,ERC2,CTNND2,RIMS2,HDAC9,TOX,SCRN1,BRINP1,PITPNC1,DNAJC6,ZEB2,TIAM2,CEP170,MAGI2,NTM,CCDC3,DLX1,GRIN3A,RAB39B,DNM1,DYNC1I1,DNM2,CPEB2,EDNRA,SEMA3D,CACNG7,EGFR,MBNL2,TENM1,RGS17,EPHA5,ETV1,EYA1,TMEM132C,DLC1,SLC9B2,OLFM1,FGFR1,SUCO,FOXF2,SYNCRIP,SGIP1,NBEA,DACH2,DKK3,MEGF10,GABRA4,CHL1,GABRB1,ILDR2,AHCYL1,SALL3,IQGAP2,GFRA2,FREM1,PCDH17,GLI2,GLRB,GNG4,B4GALNT4,GRIA2,CACFD1,GRM3,WIF1,RASSF8,KLF12,BACH2,SYNPO,CELF5,IFI16,IGFBP1,NKD1,RBPJ,IL6ST,LRRTM3,ITIH2,KCNA4,KIF5C,LSAMP,ASPRV1,MAP2,MARK1,CHIC1,MEIS2,PPM1L,SAMD5,MYH3,NASP,NDP,NFIA,NFIX,DDR2,OCRL,PAH,CNTN3,PDE4D,ENPP2,GPR85,OLA1,PCDH18,TRHDE,PRRX1,EPB41L4B,KANSL1,RASGEF1B,MAPK8,PTHLH,PTPRG,PTPRO,PTPRZ1,TMEM255A,FAT4,OXR1,RBBP6,GAL3ST4,REV3L,ZFHX4,ROBO1,ROBO2,PRR5L,CCDC112,SALL1,CSRNP3,SCN3A,TNFRSF19,NTNG1,ANKRD6,ZNF365,RADIL,SLC15A2,SCMH1,LIMCH1,RIMS1,SNCA,SOX2,TNIK,SOX11,ZHX3,NPAS3,CLASP2,TROVE2,EPB41L3,ARHGEF9,VPS13A,TAC1,SEMA4A,CAMSAP2,UNC5D,ADGRL3,TCF4,SATB2,CUX2,TCF7L2,TRIM2,PCDHB15,PCDHB7,HIF3A,TF,ASXL3,ZFP91,ERCC6L2,HEY2,KAT6B,RBFOX2,RGMB,SYNPO2,TRPS1,RFTN2,RPRM,UGT8,FLRT2,WNT7A,PCDH20,FMN2,LRP8,NAV3,KCNAB1,FAM13C,NUP214,MSRB3,FRMD6,SOCS4" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.69E-19 1.37E-15 5.19E-18 4.73E-17 42 62 "PCDH10,ANK2,CADPS,INA,RAB3C,NRXN1,FAM171B,RIMS2,JAKMIP2,ZNF804A,SPOCK3,DLG2,ELAVL2,ELAVL4,DENND4A,EYA1,FABP7,TUBB3,SGIP1,GABRB3,GAP43,SRRM4,GNAO1,GRIA2,GRIA4,KIF5C,SYTL4,SCG3,NCAM2,NEFM,NOVA1,PCDH9,STK32A,EML5,PTPRZ1,SNAP25,SCN3B,EPB41L3,SYT1,CUX2,CADM1,FSTL5" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k2_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.30E-19 1.68E-15 6.35E-18 5.79E-17 68 138 "SORCS1,PCDH19,DPP10,CASK,ASTN1,CDK5R1,CACNA1B,KALRN,VSTM2A,INA,CDH10,CHGB,CNR1,SLC35F1,FAM171B,CRMP1,JAKMIP2,HS3ST4,EDN3,EDNRB,ELAVL2,ETV1,TUBB3,FGF13,USP21,SYT17,DNER,GFRA1,GFRA2,PCDH11X,STMN2,GRM3,GRM7,GUCY1A1,GUCY1B1,KLF12,IGF1,KIF5C,MAP4,RSPO2,NAP1L2,NDP,NEFM,NOVA1,CLDN11,CNTN3,PDGFRA,GPR85,PRKAR1B,MAPK10,PRPH,FAT4,RBBP6,RTN1,SCN3A,NTNG1,ST8SIA1,CXXC4,SNAP25,PDZD2,NPAS3,ELOVL4,MTCL1,PCDHB7,HIF3A,CADM1,RPRM,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500 FaceBase_RNAseq 4.07E-19 2.08E-15 7.79E-18 7.10E-17 161 495 "ABR,PLEKHH1,KIAA1211,PTCHD1,ANK3,FGD2,EPB41L5,APOC1,SHTN1,ASCL1,ATP1A3,ATP2B1,KIF1A,FGF17,PROM1,HAP1,MAP7,INA,CDH2,ADGRG1,SRSF11,CHN2,LHX2,NRXN3,KIAA1549L,TJP2,NIPBL,IGDCC3,ABCG1,CRYM,PLCH2,CTNND2,RIMS2,ST18,CDON,DTNA,EGFR,ELAVL2,ELAVL3,ELAVL4,EMX2,OLIG2,EPB41,SLC43A2,RRAGB,ADGRV1,EYA1,F3,CLVS1,TUBB3,TUBB4A,MED12L,OLFM1,FGF12,FOXG1,ATP2C1,TPPP3,PHYHIPL,ILDR2,GAD1,GAD2,SRRM4,STARD10,KIAA1841,GCNT2,PCDH17,RUNDC3A,GLDC,TOX3,PCDH11X,MAP7D2,KCNMB4,GNG3,GPM6A,CECR2,PCLO,STMN2,GRIK2,RNF165,MFSD2A,SOX21,PSIP1,FAM107A,FAM222A,CELF3,TOX2,FRMD5,FRMD3,IGFBPL1,SHISAL1,HES5,INSM1,KCNK1,KIF5C,KIT,MAOB,MBP,SHC3,SAMD5,SCG3,MYT1,NNAT,NRCAM,PAX6,GDAP1L1,PLXNB1,NECAB2,MAPK10,SLC22A23,ELOVL2,EML5,CEP97,SUSD4,FEZF2,RBBP8,RAVER2,RTN1,SALL1,MAPK12,LINC00461,HES6,HSPA4L,SCG5,KIF21A,FERMT1,CCDC92,SMARCA4,MAST1,SNAP25,SOX2,SP4,BEX1,KANK1,FGD4,SYNE2,SYP,MTCL1,MCF2L,WWC1,WSCD1,WASHC4,CCDC173,HEY1,NR2E1,BEX4,TPD52,TRO,CA14,TST,CADM1,UCHL1,SLAIN1,NDRG4,DPYSL5,STMN4,ADAMTS9,NAV2,TMEM163,PCBP4,FZD3,FRMD6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.08E-19 2.08E-15 7.79E-18 7.10E-17 43 65 "TMCC3,PCDH10,SYT13,ANK3,APP,CDK5R1,SCAPER,RUNX1T1,INA,KIAA0408,SNAP91,NTM,ELAVL2,ELAVL4,EN2,FGF13,NSG2,NSG1,GAP43,GFRA1,GPM6A,STMN2,TOX2,SHISA6,LSAMP,NCAM1,PBX1,PCSK2,PDZRN4,RTN1,AMER2,SEMA6D,SCN3A,NAPB,SCN3B,MYT1L,KIF21B,CLASP2,TMEFF2,UCHL1,CELF4,REEP1,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Top 40 GSE76381_iPSMoleculeCountsPMLog2 4.10E-19 2.09E-15 7.80E-18 7.11E-17 66 132 "SYT13,ANK3,APBB1,APP,KIF1A,GPC2,SEPT7,CDC25B,CHGA,CRMP1,PNPLA8,SLC45A1,CTNND2,KIAA0408,ELMO1,NYAP1,SEZ6L2,ELAVL3,PRMT5,OLFM1,NSG2,NSG1,PNMA2,GABRB3,GAP43,DNER,GNAO1,GPM6A,STMN2,PTPRT,CELF3,UBE2QL1,MAP6,MARK1,CD200,SAMD14,MYO5A,BEX5,FXYD6,NCAM1,PCSK1,GNG2,SNX10,RAB3A,RGS4,RTN1,SCN3A,MRAS,RIMS1,SNAP25,MAPKBP1,SCN3B,MYCBP2,PEG10,CLASP2,SS18,SYP,SYT4,MTMR14,ASXL3,VGF,CELF4,REEP1,STMN4,SCG2,CBLN2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.15E-19 2.12E-15 7.87E-18 7.17E-17 242 855 "ABAT,ASIC2,ADCY2,RNF150,PCDH19,OSBPL6,ADGRF5,SRPX,ARHGAP20,SYT13,TRMT9B,AMPH,DPP10,ANK2,C6orf89,EPB41L5,VAT1L,TNRC6C,ARRB1,ASTN1,DYNLL1,EIF4G3,NOL4,ADGRB2,ADGRB3,NRP2,BLM,CDK5R1,OSGIN2,CA4,CA8,CA12,CACNA2D1,CALB1,KALRN,VSTM2A,RUNX1T1,CD38,CDH2,DCLK1,LGI1,CHGB,LY86,CNTN1,COL9A1,ZFP28,NSL1,CRMP1,CRYM,SNCAIP,RIMS2,CX3CR1,SCRN1,BRINP1,AIF1L,PITPNC1,ELMO1,NTM,AK5,FAM107B,CCDC3,ARNT2,GRIN3A,RAB39B,DNM1,DNM2,DUSP9,ABCC9,EBF1,EDIL3,HEYL,EEF1D,EFNA3,EGFR,PLXNC1,EPHB1,NCALD,CDHR1,EYA1,MRVI1,ST3GAL6,MED12L,SPSB4,SCARA3,FLT1,SGIP1,TRIM16,RASL10A,DACH2,GPR153,FYB1,DKK3,MEGF10,GABRA1,GABRA4,GABRB3,DENND2A,GALC,NEK6,GAP43,SYT17,DNER,IGSF5,FREM1,PCDH17,GGTA1P,BRD8,KIAA1958,ADGRA3,B4GALNT4,GRIA1,GRIA4,GRM3,PTPRT,FAM19A2,IRAK3,HAS2,UBE2QL1,NCKAP1L,HP,NEGR1,DHX35,IRF8,IGF1,IL11RA,KCNA1,KCNC2,LIG4,LSAMP,CLEC18A,SYT9,TM6SF1,AFF1,MMP16,MN1,MSR1,FXYD6,NASP,NCAM1,NCF2,NPTX1,NRCAM,NTRK2,DDR2,CLDN11,OXTR,CNTN3,PCDH8,PRTG,PDE1C,GNG2,PRRX1,SDK2,CEP41,GON4L,GDPD2,PTPRB,PTPRO,PTX3,RIPOR1,PPP2R3C,FAM184A,GAL3ST4,CRTAC1,DUSP15,RGS4,TTLL7,ZFHX4,LGI2,KIRREL1,PRR5L,EMID1,LGR4,MEG3,SALL1,CSRNP3,LRFN5,SCN2A,SCN8A,SLC30A10,ZFP2,ASRGL1,SUPT20H,TRA2B,ST8SIA1,ANKRD6,RUFY2,SLC9A5,SLC14A1,EFHD1,CXXC4,SORCS3,LIMCH1,ZC3H13,KIF1B,DDN,C11orf87,CLSTN2,SAMSN1,THSD1,NEK4,TMEM150C,ANKRD28,SYT4,CAMTA1,TAL1,ADGRL3,KLHL4,ANO4,TBX15,SATB2,ZFP90,CUX2,FAM189A1,PCDHB3,AKNA,TNS2,TEK,THBS4,HEY1,ASXL3,TLR4,TP53BP1,TPD52,NPL,RGMB,STXBP4,TRPC3,TTPA,TMEFF2,AMOT,FLRT2,WIPF1,ZNF184,INTS3,LRP8,TMEM178A,RGS7BP,MRPL47,CERS6,NETO2,NETO1" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.59E-19 2.85E-15 1.06E-17 9.63E-17 247 880 "TTYH1,ABAT,ACLY,ABHD6,KDM5D,TMCC3,PNMA8B,GRAMD1B,ADORA1,MTA3,HECW2,NR0B1,KIAA1324,BCAR3,KCNT1,AMH,KIF6,SEMA7A,USP28,GAS7,DGKD,APOC1,USP37,SHTN1,LGR5,CDC14B,KIAA1614,PPP4R4,TMEFF1,ARHGDIG,CADPS,PDE8B,MARK4,DDX3Y,ATP1A1,ATP2B3,ALDH7A1,N4BP2L1,DPY19L3,BCHE,RGS11,ZNF599,DST,ST3GAL5,SYNJ2,DDR1,VXN,MAP7,RGN,SLC16A4,SCARB1,CDH2,CACNA2D2,ADGRG1,JAM2,CLU,NMT2,CLTB,FADS2,SUMF2,COL9A3,AKAP5,MAGED1,CP,NCOR2,FEZ2,MICAL2,VCAN,CST3,PPP1R16B,ARHGEF4,GPRASP1,RIPOR2,TOX,SCRN1,DBI,DBT,JAKMIP2,ELMO1,PLPPR4,SRGAP3,CD99L2,CPEB2,RCAN1,GNE,DTNA,DTNB,MAMLD1,E2F6,EDN1,SIDT2,MRO,PLXNC1,SORBS3,CERCAM,EPS8,ERBB2,ERBB4,ETV1,RASL12,EYA1,F3,REEP2,FAM198B,FABP7,ACSL4,PTK2B,TUBB3,EFEMP1,ATP8A1,FGF13,FHL1,SEMA6C,FOXO3,AFF2,CAMKK2,CSPG5,FYN,ZMAT1,GAB1,FAM184B,BRPF3,IQGAP2,ERAP1,SEPT9,GATM,PPARGC1A,RAB30,ADGRA3,GPM6B,STON1,GPR37,RAPGEF4,MFSD2A,PADI2,HSD17B1,SHISA6,DOCK7,TUBB2B,LRRTM3,ITPKB,KCNH1,KLHL23,SYTL4,HECTD2,NCOA7,MAN2A2,SYT9,MEF2C,KITLG,PPM1L,AFF1,MOV10,MSI1,NRBP2,CTNNA3,MXI1,MYO7A,NEXMIF,FXYD6,NELL1,NFIA,NRDC,OCRL,CLDN11,PAK3,ETFRF1,PGAM2,SERPINE2,SSH1,SEMA5B,PLCB2,PLEC,MTRF1L,PSAT1,SCHIP1,PPP3CC,RASGEF1B,PRKCB,MAPK4,EPDR1,MASP1,LAMA1,PTCH1,PTPRD,PTPRE,SH3TC2,DUSP15,NUDT11,ROBO1,TMEM206,PCMTD2,GLDN,RPS6KA2,MEG3,SOX8,SOX6,MRAS,KIF21A,PPP1R9A,SH3GL2,DOCK10,ST6GAL1,ST8SIA1,SLC6A8,EFHD1,TNIK,SOX10,FNBP1,UHRF1BP1L,SPP1,ARHGAP26,TSPYL2,SMOC1,ST5,ADHFE1,PHLDB1,ACSBG1,FGD4,SYNE2,TACC1,MTCL1,SEMA4A,SIN3B,OBSL1,ZFPM2,THRA,TIAM1,DAAM2,BEX4,TPD52,NPL,TRPC3,FNDC5,TST,SGK3,LMF1,VSNL1,WNK1,SLC38A1,ADAMTS9,NAV2,WNK3,FZD3,NHSL1,NETO2,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 7.81E-19 3.98E-15 1.47E-17 1.34E-16 45 71 "PTCHD1,ALCAM,SYT13,ANK3,SMIM29,RUNX1T1,CBLN1,INA,TOX,KIAA0513,DBN1,ELAVL3,TMEM35A,RCAN2,NSG2,NSG1,FYN,JPH4,GAP43,STMN2,CELF3,UBE2QL1,NEGR1,CELF5,CD200,BEX5,NOVA1,PCDH9,TMOD2,FAT3,KIAA0895L,RTN1,SCN2A,NAPB,CXXC4,SNAP25,SCN3B,KIF21B,PEG10,SEPT3,SYT4,MTCH1,VGF,CELF4,SCG2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_500 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_500 FaceBase_ST1 9.76E-19 4.98E-15 1.83E-17 1.67E-16 140 411 "TTYH1,MTUS1,TAOK1,SPOP,APLP1,TMEFF1,ASCL1,TTC9B,BCL7A,FGF17,CFLAR,DDR1,PTBP2,PRC1,INA,CDC25B,CDH2,NOG,ADGRG1,RAB3C,JAM2,SLIT2,LHX2,RAB28,ARMC8,ACBD5,CRMP1,FEZ1,IST1,SCRN1,JAKMIP2,GSDME,EXOG,OLIG1,ABI1,ELAVL3,C8orf37,OLIG2,LRRC23,EPHB1,EXTL2,KATNAL1,REEP2,ARMCX1,FABP7,ZIC4,GORAB,FOXG1,CAP2,SLC37A3,DPYSL4,UFM1,STAMBP,NSG2,STAU2,TPPP3,C15orf41,GPR162,RUNDC3A,GLDC,PCSK1N,DCLK2,GPM6A,GPM6B,DIPK1C,TDRKH,CCDC184,STMN2,CACFD1,GSTT2,SOX21,UBE2QL1,IGSF21,FRMD5,ATCAY,NIM1K,HES5,TUBB2B,LMO1,PACRG,MAP6,CHIC1,MT3,SCG3,TAGLN3,NAP1L2,NELL2,NFIA,NFE2L2,PAK3,SLC10A4,DUSP26,GDAP1L1,GPSM2,SPATA6,MINDY2,PPP2R5E,NKAIN4,PKIA,MAPK10,GDPD1,FEZF2,DPF2,GTDC1,UBR7,PBRM1,PNMA8A,ADAL,ACER3,LINC00461,MRAS,SUPT20H,HSPA4L,SCG5,ZFP30,SH3GL3,PKNOX2,SMARCD3,SNCA,LMBRD1,SOX2,SPATA7,NPAS3,SPART,SYT11,CUX2,TCF12,AKTIP,FBXL16,HEY1,TNNT1,SSBP2,RFTN2,CLDND1,XRCC4,ZIC1,ATP6V0E2,MKRN3,SHD,PDSS2" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.32E-18 6.71E-15 2.46E-17 2.24E-16 225 784 "FMNL2,ADCY2,AXIN2,KLHL13,NR0B1,WDR35,SPARCL1,ALCAM,ARHGAP20,KCNT1,OGT,LRCH2,GPAM,APOC1,CACHD1,LRRC4C,LGR5,CDC14B,PPP4R4,ZSCAN18,NUMB,INSYN2B,SLC4A4,ATP2B3,RNF182,MPDZ,CACNA1G,WASF1,MYRF,CACNA1D,CACNB2,CALB1,ARHGEF25,SLC16A4,REPS2,CDH10,DCLK1,MAGI1,SOCS6,CHRM4,SLIT2,CNTFR,AKAP7,AKAP5,ZNF521,HAPLN1,CLIP3,TENM4,ATRNL1,VCAN,PLXNA4,CTH,BOC,DOCK4,DAPK1,ZEB2,MAGI2,SV2A,SRGAP3,DNM1,CDON,DRP2,TSPAN5,EDNRA,SEMA3D,KLHL5,FSD1L,EGFR,PLXNC1,TMEM35A,EMX2,LRRC17,NRN1,ABCA8,FAM198B,FABP7,KIAA1109,CAP2,IP6K2,FLNC,AFF2,NOP56,ST6GALNAC3,NSG1,ZMAT1,GABRA4,GABRB1,DENND2A,GALC,GATM,SESN1,GFRA2,FREM1,CSDC2,GHR,PCDH11X,ADGRA3,GPM6B,FUT10,LPAR4,GPR37,RABL2A,GUCY1A2,GUCY1A1,GUCY1B1,ATG4C,TCEAL6,IGF1,NKD1,IL6ST,KCND2,KLHL23,MAP2,MATN2,CHIC1,MEIS1,KITLG,MOV10,SESN3,CCDC80,MTR,MXI1,LAYN,MYO9A,NEXMIF,NCAM1,ZC3H12B,NEFM,NELL1,NFIA,NNAT,NME4,NPR2,ETFRF1,PDE1A,PDGFRA,CDK14,SERPINI1,PIK3R1,FXYD1,PCDH18,PRRX1,FAT3,PPP3CC,PRKACB,PRKCB,LAMA1,GDPD2,CNTLN,PTN,ZIK1,PTPN13,PTPRD,PTPRG,TMEM255A,FAT4,ZCWPW1,REV3L,RNASEL,ZFHX4,ROBO2,TMEM206,RPS6KA2,LGR4,MEG3,HUNK,ATAT1,KCNIP1,ZNF354C,AP1AR,SEMA6D,SATB1,SCN2A,PRCD,TNFRSF19,STUM,RASA3,ST8SIA1,DZIP1,SLC4A3,SCMH1,ATF7IP,PALLD,ZCCHC24,KDM3A,UHRF1BP1L,PEG10,NPAS3,TROVE2,SMOC1,ST5,SULF2,SYNE2,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,SZT2,PSD3,OBSL1,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,KAT6B,TNNT1,TPM1,TRPS1,FNDC5,DCBLD1,TST,AMOT,FLRT2,PLEKHH2,VAV2,VSNL1,ZNF711,LYPD6,ZNF189,ADAMTS9,NAV2,WNK3,FRMD6,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Subtype_iMN2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.35E-18 6.87E-15 2.51E-17 2.29E-16 44 69 "SEMA6A,SYT13,ANK3,RUNX1T1,INA,SNAP91,CPEB2,SEZ6L2,PLEKHA1,ELAVL3,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,DKK3,GAP43,STMN2,PTPRT,CELF3,CELF5,HS6ST3,BEX5,PCSK1,TMOD2,RIT2,RTN1,SCN2A,NLGN1,NAPB,SNAP25,SCN3B,FAM219A,KIF21B,PEG10,EPB41L3,SEPT3,SYP,SYT4,DNAJC12,VGF,TCEAL7,CELF4,SCG2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.60E-18 8.16E-15 2.97E-17 2.70E-16 84 196 "TTYH1,SLITRK1,PHF12,SHTN1,ATP2B2,MPDZ,DIRAS1,ARHGAP33,ADGRG1,SRSF11,PCYT1B,CRMP1,NCAN,SLITRK5,SCRN1,DCC,KBTBD11,DTNA,FSD1L,ELAVL3,OLIG2,EPHB1,APC2,ADGRV1,CLVS1,ZIC4,TUBB3,FOXG1,AFF2,NSG2,DLL3,FYN,BRPF3,SRRM4,RUNDC3A,DCLK2,STMN2,GRIK2,RNF165,CELF3,TOX2,FRMD5,IGFBPL1,CELF5,ATCAY,HES5,KCNH2,MAP2,MARK1,SHC3,TAGLN3,MYT1,NRCAM,TMOD2,GDAP1L1,MAPK10,GAL3ST4,ASRGL1,SCG5,SLC1A2,FAM81A,CXXC4,SOX11,LHFPL4,NPAS3,STAU1,GSE1,SYP,TACC1,TMEM178B,WSCD1,ACSL6,CUX2,CLASP1,FRYL,BHLHB9,TUB,MGAT5B,ZIC1,ZIC3,DPYSL5,STMN4,WNK2,FZD3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.84E-18 9.40E-15 3.39E-17 3.09E-16 30 36 "PCDHGB4,ADGRG1,CNTN1,DBI,NTM,OLIG1,EDNRB,OLIG2,ETV1,FABP7,C1orf61,LUZP2,GPM6A,SCRG1,HES5,SHC3,MT3,SCG3,PDGFRA,SERPINE2,PMP2,NKAIN4,PTN,PTPRZ1,S100B,BCAN,SIRT2,ZCCHC24,SOX10,PCDH15" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.84E-18 9.40E-15 3.39E-17 3.09E-16 30 36 "PCDHGB4,ADGRG1,CNTN1,DBI,NTM,OLIG1,EDNRB,OLIG2,ETV1,FABP7,C1orf61,LUZP2,GPM6A,SCRG1,HES5,SHC3,MT3,SCG3,PDGFRA,SERPINE2,PMP2,NKAIN4,PTN,PTPRZ1,S100B,BCAN,SIRT2,ZCCHC24,SOX10,PCDH15" Coexpression Atlas PCBC_SC_fibroblast_1000 Progenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 2.15E-18 1.10E-14 3.94E-17 3.59E-16 269 992 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY5,GALNT13,ADD2,UNC5A,PTCHD1,NLGN4X,SEMA6A,PDZD4,CNIH2,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,AZGP1,ADGRB1,LDHD,SYT6,BRSK2,MAP7,CBS,CLDN10,CCK,SYNGR3,CDH8,DLGAP1,CACNA2D2,CHGA,RAB3C,DLGAP3,SLC24A2,FAM189A2,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,SEC14L5,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,HS3ST4,HS3ST2,CALN1,FAM57B,SLC25A18,FAM78B,USH1C,ST8SIA3,AASS,LINC00599,ELAVL2,RASGRP2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SPSB4,ACTL6B,C1orf61,SYT3,CSPG5,B3GAT1,TMEM151A,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,SALL3,ATP8A2,SRRM4,IGSF5,GFRA2,GLDC,PCDH11X,LUZP2,GNG3,GNG4,GPM6A,GPM6B,GPR19,LPAR4,CECR2,GRIA4,GRIK5,GRIN1,ADAMTS8,GRM3,GRM8,LINGO1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,PLD5,IGSF1,RIPPLY2,TUBB2B,LRRTM3,ITGAM,KCNA6,KCND1,KCND2,KCNJ11,KCNN1,KCNN2,KCNN3,KCNQ2,KHK,KIF5A,KIF5C,CAMK2N2,FGFBP3,C2orf80,MATK,CHST6,SCAMP5,CPNE9,JAKMIP3,SCG3,DDX25,TCEAL5,FXYD7,RCOR2,NELL2,NODAL,NPTX1,HCN1,ZDHHC22,PAH,NLGN3,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,NECAB2,MAGEL2,EPB41L4B,PACSIN1,FA2H,PPP2R2B,NKAIN4,RAB39A,SMIM10L2B,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,SLC25A48,FAM184A,ZMAT4,RET,RIT2,LGI2,RORB,MRAP2,SGSM1,RIMKLA,SYNDIG1,HUNK,RYR1,SALL1,SCN4B,TMEM200C,SH3GL2,SH3GL3,PPM1E,CNKSR2,BCAN,SLC1A6,LRRC55,SLC8A2,SEPHS1,SHANK2,SLCO1A2,TET1,OGDHL,IGSF9B,SNCB,SOX2,SOX3,SOX15,NMNAT2,LHFPL4,BEX1,SOX21-AS1,SEPT3,ACSBG1,ZFR2,RHBDL3,ARC,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,PCDHA6,PCDHA3,PCDHA2,RNF175,TEX15,CHST8,GALNT17,ENHO,RELL2,TLL2,FAM124A,ANKRD24,PIK3R5,CA14,RPRM,UGT8,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,TMEM198,DPYSL5,SLC30A3,CADM2,XKR7,GAL3ST3,RGS7BP,NETO1,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.20E-18 1.12E-14 4.01E-17 3.66E-16 58 110 "CADPS,ASCL1,ADGRB3,DCLK1,CRMP1,CSNK1E,ST18,KIAA0408,TCAF1,JAKMIP2,GSDME,EDNRB,ELAVL2,ELAVL3,ELAVL4,FABP7,TUBB3,DPYSL4,NSG2,DLL3,MEGF10,GAP43,DNER,TOX3,STMN2,RNF165,HMGCR,HES5,INSM1,KIF5C,TAGLN3,NAP1L2,NEFM,NEUROD1,PCDH8,SLC10A4,GNG2,MAPK10,PTPRZ1,FIGN,RGS4,ZFHX4,DRAXIN,LINC00461,SNAP25,SOX2,SOX5,TROVE2,GSE1,CLASP1,PRMT8,CADM1,ZIC1,ZIC3,ZNF24,PCBP4,SLC17A6,VANGL2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.31E-18 1.18E-14 4.21E-17 3.84E-16 43 67 "THSD7A,INA,SEPT7,ZNF521,DCC,EBF1,ELAVL2,ELAVL3,ELAVL4,NRN1,TUBB3,GABRB3,NKX6-2,GAP43,GPM6A,STMN2,GRIA2,C1QL4,NEGR1,INSM1,KIF5C,CD200,TAGLN3,NAP1L3,NCAM1,NEFM,NNAT,PCDH9,PCSK1,GDAP1L1,PLPPR1,ROBO2,RTN1,CSRNP3,SCN3A,SYBU,CXXC4,SEPT3,SYT4,FAM155A,UCHL1,CELF4,SENP7" Coexpression Atlas PCBC_ratio_SC_vs_DE_500 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 2.43E-18 1.24E-14 4.41E-17 4.02E-16 160 499 "TTYH1,SYN3,UNC5A,VAT1L,PLA2G4C,ATP1A2,ATP1A3,AZGP1,LDHD,CA4,CALB2,SYT6,VSTM2A,CCK,CHGA,CHRNA4,CHRNB2,RAB33A,NRXN2,CLU,SLC24A2,CNTN1,CABP1,ANKRD35,HS3ST5,C1QL2,ABCG1,SNCAIP,GALNT9,RIMS4,SLC45A1,SEC14L5,RIPOR2,TOX,PHYHIP,JAKMIP2,TMEM130,PARD6A,NTM,AK5,ATL1,CACNG7,AASS,LINC00599,CALCRL,RASGRP2,SEZ6,ANKRD13B,PIPOX,CEND1,OLFM1,ACTL6B,HPCAL4,CGREF1,TMEM151A,JPH4,ACSS1,CPLX2,DNER,IGSF5,ALDH1L1,TTBK1,RND1,CCDC184,GRIA4,GRIN1,SOX21,LINGO1,WIF1,NXPH2,HRH3,FRMD3,INSYN1,LRRC75A,BTBD17,SCIN,RIPPLY2,LRRTM3,ITGAM,KCNH2,KCNMA1,KCNN2,KCNN3,KHK,CREG2,KIF5A,FGFBP3,CPNE9,MX1,FXYD7,SLCO1C1,VWA2,NPTX1,NPTX2,NTRK3,ZDHHC22,PAH,PCSK1,NLGN3,CAMKV,ST8SIA5,FXYD1,PLP1,PCDH18,SEPT4,EPB41L4B,POU3F4,NKAIN4,RAB39A,GDPD2,NCR3LG1,PTPRN2,PTPRO,PTX3,TMEM145,PYGM,SUSD4,RADX,ARHGEF10L,KCNIP1,RYR1,SCN4B,ELMOD1,IL17RB,SCG5,FERMT1,SLITRK3,BCAN,LRRC55,TRERF1,KIF21B,LMO3,SOX21-AS1,INKA2,SEPT3,ACSBG1,ABCC8,RHBDL3,ARHGEF9,ARC,SYP,SYT5,TAC1,TAC3,TACR1,ACSL6,TMEM151B,TLL2,TNFRSF1B,TTPA,VAV1,VAV2,VSNL1,TSPAN11,LGI4,CRB2,LAMP5,SLC30A3,KCNAB1,TMEM163" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4 Gudmap RNAseq 2.57E-18 1.31E-14 4.65E-17 4.24E-16 302 1151 "DPF1,SERPINA3,EMILIN3,METAP1D,NDRG2,RNF157,GRAMD1B,HECW2,PCDH19,NME5,OSBPL6,CC2D2A,SEMA6A,ALCAM,SRPX,LTBP4,PDZD4,SMIM29,PPFIA2,CNIH2,GAS7,VAT1L,TNRC6C,KIAA1614,TMEM263,IGDCC4,MARCH3,RASL11B,ASTN1,ZNF583,CADM3,NOL4,ADGRB2,BBS2,SEC11C,LDHD,JAZF1,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,ARHGEF25,REPS2,LONRF2,DCLK1,EVI5L,CDO1,CRLF1,NUMBL,CHGB,NRXN1,PCYT1B,ABI3BP,ZNF521,CNRIP1,FAM171B,ANKRD44,CLIP3,SNCAIP,CSF1,TENM4,CSF3R,ATRNL1,VCAN,SOCS5,KIAA0040,PLCXD3,DCAF4,PYGO1,CYBB,BOC,HDAC9,ARHGAP24,TOX,ZFYVE16,BRINP1,RABGAP1L,DLG4,DMD,DNM1,SHANK1,EDN3,EDNRA,SEMA3D,TMTC1,EFNA3,EGFR,RASA4,SORBS3,CERCAM,ELN,TMEM35A,EPB41L2,DENND4A,IGSF6,SPEG,EXTL1,HSPA12B,TBC1D16,EFEMP1,GORAB,MED12L,FGF11,SCARA3,ZMYND15,EVL,FLNC,SGIP1,AFF2,COQ5,WDR83,NBEA,USP21,GPR153,NSG1,FUT9,TMEM151A,NRG3,PHYHIPL,DKK3,GABRA3,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,RUNDC3A,GK,HPGDS,GNAO1,GRK4,GRIA4,PRDM5,LINGO1,FAM107A,SLC2A6,MAP4K5,IRAK3,HAS2,KLF12,INSYN1,SYNPO,CFAP126,NEGR1,CPT1C,ICA1,IGF1,BRINP3,DIPK1A,LRRTM3,KCNA6,KCNJ16,LAMA2,LRRC4B,STMN1,VWA5A,LSAMP,SMAD9,MAP2,MATN2,MGAT3,MMP16,MN1,SAMD5,ADAM22,NRBP2,TAGLN3,MYBPC1,MYO7A,NCAM1,ZC3H12B,NELL1,NFIA,NPY,NPR2,DDR2,NUCB2,PAK3,PCSK5,ENPP2,GPR173,PENK,PFKFB4,CDK14,PGAM2,NLGN3,ZFYVE21,TMEM38A,PCDH18,PMP22,LRP12,EPB41L4B,SLC36A4,POU6F1,PPP2R2B,PPP3CC,PRKAR1B,MAPK4,EPDR1,MAPK9,MASP1,MDGA2,CNTLN,PTH1R,PTPRD,PTPRE,PTPRZ1,PTX3,TMEM231,CCDC40,FAT4,ZCWPW1,BEND5,PRRT2,ROBO2,TCP11L1,LRRK2,MEG3,STX1B,CCDC112,SEMA6D,LRRTM4,FAM19A1,PRCD,TNFRSF19,SOX6,TRIM46,GALNT10,ZFP30,SH3GL3,NTNG1,CNKSR2,NLGN1,ST8SIA1,DZIP1,FAM81A,RUFY2,SLC6A8,ARHGEF40,CCDC88A,SLIT1,SMARCD3,RIMS1,SNAP25,PALLD,PDZRN3,DOP1A,TNIK,SOX5,KIF21B,ARHGAP26,ATP10B,CLSTN2,SST,EPB41L3,NKAIN2,STAC2,SULF2,ARHGEF9,PLCB1,ANKRD12,ADGRL3,EHBP1,PSD3,SIK3,TF,ZFPM2,SLC44A1,THRA,KCTD2,KAT6B,PIK3R5,NPL,LRRC24,SSBP2,RFTN2,TUBB2A,CADM1,FLRT2,PLEKHH2,PLPPR2,CCDC136,MICAL1,VSNL1,WNT7A,PORCN,ZNF711,ZNF32,KCNT2,AGMO,SHD,NAV3,PPP1R3F,PLD4,CERS6,FAM219B,ADAMTS10,FRMD6,NETO2,DPF3,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.87E-18 1.46E-14 5.17E-17 4.71E-16 269 994 "TTYH1,CDC7,ERMN,PLEKHH1,AP2A2,EPB41L5,APOC1,SHTN1,TMEFF1,ZFYVE28,PTCH2,TMEM108,ATP2B2,KIF1A,ADAM23,TTLL9,BCHE,PROM1,DST,CA4,CA12,THSD7A,DIRAS1,HAP1,PTBP2,MAP7,CBLN1,CCNT1,INA,ARHGEF1,CDK11B,CDH2,LRRFIP1,CCPG1,CBARP,LHX2,PLAA,CLCN3,KIAA1549L,NRXN2,NMT2,DNAJB5,C4orf33,MAP4K4,NIPBL,COX4I1,IGDCC3,NECTIN3,SLC35F1,FAM171B,RBM39,CLIP3,LRRC3B,SUSD5,NCAN,SLITRK5,GREB1,CTNND1,CTNND2,RIMS2,KATNAL2,INTS1,DAPK1,JAKMIP2,CHRDL1,RAB39B,DTNA,DUSP9,ST8SIA3,PHF20L1,APH1A,PLXNC1,EIF4G2,ELAVL2,ELAVL3,PAN3,EMX2,OLIG2,PLEKHO1,EPB41,SEZ6,EPHB1,NCALD,APC2,MRPL10,PIPOX,RRAGB,CEND1,ADGRV1,REEP2,TUBB3,TUBB4A,POLR1B,FGF11,TMEM164,FHL1,AGAP3,FOXM1,FLNC,NOP56,SYT3,COQ5,NSG2,DLL3,FUT9,MPP6,PHYHIPL,GABRB3,ILDR2,SALL3,HIGD1B,SEPT9,SRRM4,GATM,CSDC2,GGTA1P,PPARGC1A,BRD8,GLDC,GLS,TOX3,ZNF638,MAP7D2,GNG3,GPD2,CECR2,PCLO,STMN2,RFFL,GRIK2,GRIK5,RNF165,SOX21,CELF3,TOX2,FRMD5,MIER3,IGFBPL1,USP51,DHX35,LRRC75A,HSP90AA1,SHISAL1,LRRCC1,TJAP1,HES5,LRRTM1,CDH20,KLHL23,KCNK1,KTN1,LIFR,MAOB,MAP2,PPM1L,CPNE9,CCDC80,ADAM22,THYN1,MYCN,MYO6,NME4,NOVA1,NRCAM,IGSF11,PAK3,PAX6,PRTG,PIK3C2A,ANLN,SNX10,SLC25A23,PLTP,PMP22,MAGEL2,NXPH1,POU3F4,FSD1,NKAIN4,MASP1,RELN,GDPD2,ELOVL2,PTPN13,EML5,PTPRZ1,CCDC40,FEZF2,RBBP8,GAL3ST4,FIGN,RFX3,RFX4,MYH14,FBXW7,STK32B,PTGR2,YJEFN3,CCDC112,SALL1,MAPK12,HSPA4L,SCAF8,SCG5,ZFP30,KIF21A,ARX,NTNG1,FHOD3,CCDC92,NUBPL,TET1,INTS9,SNRPN,SOX2,SOX5,SP2,BEX1,LHPP,LMO3,C11orf87,RGL1,SEPT3,AJAP1,SYT11,FGD4,PRRC2C,SYN1,MTCL1,ROBO3,WWC1,TCF4,TCF7L2,WASHC4,C18orf54,NR2E1,LRRC8A,BEX4,TPM3,WBP2,PRMT8,STXBP4,ZMYND8,TST,TUB,SLAIN1,MGAT5B,CCDC14,RBFOX3,ZIC2,ZIC3,ZNF23,ZNF24,ZBTB16,EML6,DPYSL5,CA10,SHD,SLC38A1,RGMA,STOX2,ADAMTS9,TMEM163,CAB39L,WNK3,PDSS2,FZD3,SOCS4,SPATA13" Coexpression Atlas Arv_SC_fibroblast_1000_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 2.93E-18 1.49E-14 5.26E-17 4.80E-16 173 556 "SYN3,CSMD2,TMEM132B,ADCY2,GALNT13,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,KIF1A,ADGRB1,HAP1,SYT6,BRSK2,MAP7,CLDN10,SYNGR3,CHGA,RAB3C,DLGAP3,FAM19A5,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,RIMS4,CNTNAP2,SEC14L5,RIMS3,KCTD8,BRINP1,HS3ST4,CALN1,FAM57B,DPP6,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,IGSF5,GLDC,PCDH11X,GNG3,GNG4,GPM6B,LPAR4,CECR2,GRIA4,GRIN1,GRM3,LINGO1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,RIPPLY2,TUBB2B,KCND2,KCNN1,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,CHST6,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,EPB41L4B,PACSIN1,PPP2R2B,RAB39A,GDPD2,PTPRZ1,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,HUNK,RYR1,SALL1,TMEM200C,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC8A2,TMEM132D,SLCO1A2,IGSF9B,SNCB,LHFPL4,SOX21-AS1,SEPT3,ZFR2,ARC,COBL,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,CA14,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.87E-18 1.97E-14 6.92E-17 6.31E-16 58 111 "DPF1,PCDH10,ASCL1,PTCH2,ATP1A3,DDR1,ARHGAP33,NRXN3,CRMP1,CSNK1E,NCAN,ELMO1,KBTBD11,DLX1,EDNRB,ELAVL3,APC2,TUBB3,DPYSL4,NSG2,GAD1,GAD2,ACSS1,RUNDC3A,DCLK2,GPM6A,GPM6B,GRIK3,MFSD2A,FAM222A,CELF3,HES5,LRRC4B,MARK1,MBP,MSI1,MYT1,NNAT,TMOD2,GDAP1L1,POU3F4,PROX1,RTN1,LINC00461,SCG5,MAST1,SNAP25,LHFPL4,NPAS3,ACSBG1,TACC1,MCF2L,HEY1,UCHL1,ZIC3,CELF4,TMEM198,STMN4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.99E-18 2.04E-14 7.12E-17 6.49E-16 133 388 "ADCY2,PCDH19,SORCS2,C1QTNF3,SPARCL1,ARHGAP20,SYT13,IGDCC4,CASK,CADPS,DOCK11,IL33,CACNA2D1,RUNX1T1,LDB2,CCNH,AP4M1,REPS2,CDH2,CDH10,RCBTB2,ZNF521,FAM171B,HAPLN1,RNF14,NCOR1,GPSM1,BOC,RASSF2,HP1BP3,SRGAP3,NTM,EBF1,EDIL3,ATL1,SEMA3D,TMTC1,EFNA3,EFNB3,EGFR,PLXNC1,ELAVL2,CALCRL,EFS,EFEMP1,GAB1,CHL1,GFRA2,GHR,GLI2,GLRB,RAB40B,GPT2,GPM6B,GRIA1,GRIA4,HAS2,UBE2QL1,KLF12,NEGR1,IGF1,NKD1,KCND2,VWA5A,MAOB,MAP2,MATN2,MEIS1,MEIS2,MMP16,MN1,MTR,MYH3,FXYD7,NFIX,NNAT,DDR2,CLDN11,ZNF827,PCDH8,PDGFRA,GPR173,GPR85,PIK3R1,FTO,PCDH18,PLTP,PRRX1,MED1,PTCH1,PTPRD,FAT4,RBBP6,TSPY26P,RNASEL,ZFHX4,LGI2,TMLHE,MEG3,SATB1,CSRNP3,FAM19A1,NTNG1,DZIP1,MTERF2,SLN,MAPKBP1,PDZRN3,TROVE2,CLSTN2,EPB41L3,SYT1,ADGRL3,KLHL4,ANO4,EHBP1,VWC2,PCDHB7,TEX15,ZFPM2,ITGB3BP,HHIP,TNNT1,TPM1,TPM2,TRIO,SSBP2,TUBB2A,LYPD6,RGMA,RTN4,SSPN,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.05E-18 2.07E-14 7.20E-17 6.56E-16 235 837 "CPNE2,ABAT,KDM5D,FMNL2,ADD1,MTA3,HECW2,KLHL13,NR0B1,ARHGAP20,KCNT1,SEMA7A,GAS7,CACHD1,SHTN1,LGR5,KIAA1614,PPP4R4,IGDCC4,TMEFF1,CADPS,NUMB,DDX3Y,ATP1A1,ATP1A2,SLC4A4,ATP2B3,ALDH7A1,RGS11,DST,ST3GAL5,SYNJ2,WASF1,CALB1,RGN,SLC16A4,CDH2,CDH10,DCLK1,MAGI1,CDO1,TBRG4,ADGRG1,CHRM4,FADS2,QKI,MAGED1,HAPLN1,VCAN,PLXNA4,FAM169A,CTNND1,NOS1AP,DOCK4,DAPK1,SCRN1,DBI,DCT,ELMO1,G3BP2,USP3,CDON,DRP2,RCAN1,DTNA,DTNB,RASGRP1,SIDT2,MRO,PLXNC1,LPAR6,SORBS3,TMEM35A,EMX2,EPB41L1,MTSS1L,EPS8,NRN1,REEP2,ABCA8,FAM198B,PTK2B,ST3GAL6,SUCO,UBE2E3,SEMA6C,AFF2,NOP56,JKAMP,CAMKK2,FYN,GABRA4,GABRB1,TRAF3IP2,BRPF3,GALC,SEPT9,GART,GATM,PPARGC1A,GLUL,PCDH11X,OS9,ADGRA3,GPM6B,GPR37,RAPGEF4,BVES,PACSIN2,SHISA6,INPP1,TUBB2B,LRRTM3,KCND2,KCNH1,KLHL23,KCNK2,SYTL4,NCOA7,MAN2A2,MAOB,MATN2,MEIS1,KITLG,AFF1,MSI1,NRBP2,CTNNA3,MTR,MYBPC1,MYO9A,RCOR2,NELL1,NFIA,SLC11A2,NUCB2,ZNF827,PAK3,PDE2A,PDGFRA,SLC10A4,ABCB1,SERPINE2,SERPINI1,PIK3C2A,SMOX,PCDH18,MTRF1L,FAT3,PPP2R5C,PPP3CC,RASGEF1B,PRKCB,GDPD1,MDGA2,PTCH1,PTPN13,PTPRE,PTPRG,PEX2,SH3TC2,RBBP8,DUSP15,REV3L,RNASE1,ZFHX4,ZNF532,ROBO1,TMEM206,GLDN,RPS6KA2,LGR4,HUNK,SEMA6D,TNFRSF19,SOX6,STUM,MRAS,RASA3,KIF21A,FAM102A,PPP1R9A,FRMPD1,DOCK10,ST6GAL1,ST8SIA1,SLC4A3,EFHD1,SNCA,TNIK,SOX5,KDM3A,UHRF1BP1L,SPP1,PEG10,ARHGAP26,CDK19,TSPYL2,SMOC1,LRRC4,ST5,ADHFE1,FGD4,SUPT5H,TACC1,ADGRL3,SZT2,DOCK9,OBSL1,TEX15,DNAH7,ZFPM2,TIAM1,HEY1,ACTR6,DDHD1,BEX4,TNNT1,TPD52,RUNDC3B,FNDC5,TST,VAV2,PCDH20,ZNF23,ELFN1,SPIRE1,INTS3,SLC38A1,ADAMTS9,NAV2,WNK3,NHSL1,NETO2,DPF3" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.14E-18 2.11E-14 7.34E-17 6.69E-16 225 791 "EMILIN3,NDRG2,ADD1,ADD3,PNMA8B,TAOK1,SRPX,ARHGAP20,PCDH10,LTBP4,LCORL,PKP4,APLP1,CASK,ARHGAP5,ASPH,PTCH2,DDX3Y,ATP1A2,ATP2B1,RNF182,DOCK11,BACH1,ADGRB3,SGCE,IL33,BTRC,VSTM2A,RUNX1T1,LDB2,DCLK1,ZNF445,SRSF11,CHM,SLIT2,KMT2C,NRXN3,PLAA,NMT2,COL4A5,COL9A2,FAM171B,RBM39,CLIP3,TENM4,CSF1R,FEZ1,DZIP3,PLCXD3,PUM1,CX3CR1,FGFR1OP2,GAPVD1,TCAF1,RIPOR2,AIF1L,GIT2,ZEB2,ZC3H11A,GSDME,CDON,ABCC5,ABCC9,EDNRA,SEMA3D,CACNG7,APH1A,EIF4G1,ELN,CALCRL,EMX2,EPB41L2,LRRC17,SRRM1,TMEM132C,SCML2,FCGRT,KIAA1109,FGF1,MEX3B,SEMA6C,ANKFY1,NBEA,SMC2,APOPT1,GABRA4,GABRB1,ILDR2,GAD1,TUBGCP4,SRCAP,CSDC2,GLRB,TNRC6A,GLUL,PCDH11X,HTATSF1,LPAR4,STMN2,DIDO1,PARD3B,GRIK1,NR3C1,PRDM5,GRM7,CIT,GSN,KIF3A,KAT7,WIF1,RASSF8,HAS2,KLF12,MIER3,IGF1,KCND2,KCND3,VWA5A,LSAMP,MAP4,MATN2,CHIC1,MEF2C,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,MYBPC1,NASP,NCAM1,NFIA,NFIX,CNOT4,OCRL,PCDH9,PCSK5,PDGFRA,PDPK1,GPR85,PENK,OLA1,NALCN,PIK3R1,PLEC,FXYD1,PLTP,RC3H2,PRRX1,SDK2,FAT3,SH3KBP1,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,LGI2,TMLHE,ROBO2,MRAP2,MEG3,NCBP3,ATXN1,ATXN2,LRRTM4,FNIP1,SFPQ,TRA2B,ARX,CHD9,WDR37,SLC12A2,SCMH1,TET1,CPEB4,ARFGAP1,ZKSCAN3,CXXC4,SNAP25,SNCA,ZCCHC24,ZC3H13,KIF1B,RBM26,TROVE2,PRRC2C,SYNE2,ANKRD12,KLHL4,WASHC4,CLASP1,PCDHB9,OBSL1,AHCYL2,HIF3A,HHIP,CBX5,ASXL3,R3HDM1,TNS1,RBFOX2,TPM1,NR2C2,TRIO,TRPS1,TSC1,SSBP2,UBE3A,UBTF,FLRT2,FLRT1,VLDLR,PCDH20,ZNF711,ZNF142,PMEPA1,ADAMTS9,NAV2,SNX27,FIP1L1,JMJD1C,GAN" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000 FaceBase_RNAseq 4.20E-18 2.14E-14 7.42E-17 6.76E-16 264 973 "EMILIN3,NCKAP5,ACTN2,NDRG2,ADCY2,ERMN,PLEKHH1,PTCHD1,PCDH19,ARHGAP20,LTBP4,GPRASP2,FGD2,KCNAB2,EPB41L5,APOC1,SHTN1,CDK10,ASCL1,ASTN1,ADGRB2,FGF17,BLM,PROM1,C1QC,CACNA1G,LDLRAD4,CA4,CACNA1B,CACNA2D1,DIRAS1,HAP1,MAP7,LRBA,REPS2,LONRF2,KCNAB3,CDO1,CRLF1,ADGRG1,SRSF11,CBARP,LHX2,NRXN3,CLCN3,KIAA1549L,NRXN1,MYL6B,TMEM59L,TJP2,IGDCC3,CREB5,ANKRD44,ABCG1,CRYM,CSF1R,FEZ1,OSBPL3,PLCH2,CNTNAP2,FAM169A,GREB1,ST18,TOX,SPOCK2,C8orf34,RUSC2,RABGAP1L,CCDC3,CHRDL1,DLG2,DLG3,DMD,CDON,SHANK1,DTNA,DUSP9,MAMLD1,SEMA3D,EGFR,ELAVL2,ELAVL3,ELAVL4,RGS17,ELN,TMEM35A,EMX2,EPB41,LRRC17,EPHA5,APC2,RRAGB,ADGRV1,EYA1,ACSL4,TUBB3,CHST15,FCGRT,FGF11,FHL1,FOXG1,TRIM16,KHDRBS3,DLL3,FUT9,NRG3,FYB1,PHYHIPL,ILDR2,GAD1,GAD2,JPH4,TMEM8B,SRRM4,STARD10,KIAA1841,PCDH17,PPARGC1A,ZNF276,GLDC,GLRB,TOX3,PCDH11X,MAP7D2,CECR2,PCLO,NR3C1,GSN,MFSD2A,SOX21,PSIP1,FAM107A,FAM222A,WIF1,TOX2,FRMD5,FRMD3,SYNPO,IGFBPL1,NEGR1,SHISAL1,HES5,IL11RA,KCNH2,KLHL23,KCNK1,KIT,KTN1,VWA5A,MAOB,AQP11,MBP,IL17D,MEIS1,MEIS2,SRSF12,CD200,CCDC80,MSI1,HS6ST3,MYCN,NEXMIF,TCEAL5,NCAM2,NELL2,NFIA,NFIX,NNAT,NRCAM,CNTN3,PAX6,PCDH9,PRTG,PDE1A,SNX10,TMEM38A,PLCL1,PLXNB1,NECAB2,NXPH1,POU6F1,PRODH,GDPD1,MDGA2,PSMD13,ELOVL2,PTPN13,EML5,RAB3A,ACSS3,SUSD4,GAL3ST4,ZMAT4,FIGN,RFX4,ZFHX4,MYH14,RAVER2,EMID1,LGR4,SOX8,TRAPPC13,DGLUCY,SALL1,MAPK12,ATXN1,LRRTM4,LINC00461,KIF21A,FERMT1,DOCK10,NTNG1,CCDC92,NLGN1,SLC1A2,MAST1,SOX2,SP4,NMNAT2,NPAS3,LMO3,CLSTN2,SMOC1,ZFR2,PLCB1,SEMA4A,MCF2L,ADGRL3,WWC1,WSCD1,CUX2,WASHC4,PHF24,FAM189A1,PSD3,HEY1,NR2E1,TPD52,TRPS1,KCNE5,CA14,CADM1,SLAIN1,FLRT1,TSPAN11,ZIC2,FMN2,ZBTB16,DPYSL5,LAMP5,TFIP11,PMEPA1,CADM2,LRP8,SLC38A1,ADAMTS9,PCDH15,NAV3,NAV2,TMEM163,PCBP4,FZD3,SPATA13,SENP7" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.35E-18 2.22E-14 7.64E-17 6.96E-16 63 127 "SLITRK1,PLEKHH1,PTCHD1,FGF17,HAP1,INA,ADGRG1,CLCN3,NRXN2,CRMP1,NCAN,SLITRK5,RIMS2,SRGAP3,KBTBD11,DTNA,ELAVL2,EPHB1,RRAGB,EXTL2,ADGRV1,REEP2,FABP7,TUBB4A,SPSB4,DLL3,GABRB3,AHCYL1,SRRM4,TOX3,GPR19,TUBA1C,STMN2,GRIK3,RNF165,CELF3,TOX2,FRMD5,DDX19B,CELF5,ATCAY,ZIC5,HES5,MSI1,NRCAM,NLGN3,MAPK10,PROX1,RTN1,HSPA4L,SCG5,SOX2,SYP,MCF2L,WSCD1,ACSL6,SLAIN1,MGAT5B,ZIC1,ZIC3,DPYSL5,FZD3,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.36E-18 2.22E-14 7.64E-17 6.96E-16 75 167 "SORCS1,PCDH10,DPP10,PPFIA2,VAT1L,CADPS,CACNA1B,BRSK2,CDH10,DCLK1,CHGB,SYNPR,CNR1,CNTN1,AKAP6,MYRIP,FAM171B,CRYM,NRSN1,JAKMIP2,CHRDL1,GRIN3A,ST8SIA3,ELAVL2,ELAVL4,EPHA5,EYA1,TMEM132C,FGF13,UBE2E3,FOXF2,SGIP1,DACH2,MEGF10,GABRA1,GAP43,DNER,STMN2,GRM7,FAM19A2,WIF1,IFI16,INSM1,MAP4,RSPO2,MYH3,NAP1L2,NDP,NEFM,NTRK2,CLDN11,CNTN3,GPR85,NALCN,TRHDE,PRRX1,MAPK10,PRPH,RET,RGS4,ZFHX4,SALL1,CSRNP3,SCN3A,FAM19A1,SNAP25,SCN3B,SOX2,C11orf87,TAC1,ACSL6,HHIP,TIMP4,SYNPO2,AGMO" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K1 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 6.50E-18 3.31E-14 1.14E-16 1.03E-15 100 259 "PLEKHH1,EPB41L5,ZFYVE28,KIF1A,ADAM23,PROM1,DST,THSD7A,PTBP2,CDK11B,CDH2,CCPG1,LHX2,KIAA1549L,NRXN2,NMT2,C4orf33,NIPBL,IGDCC3,NECTIN3,SLC35F1,FAM171B,CLIP3,SUSD5,CTNND1,CTNND2,RIMS2,KATNAL2,JAKMIP2,RAB39B,PHF20L1,PLXNC1,EIF4G2,ELAVL2,PAN3,EMX2,EPB41,FHL1,FUT9,MPP6,PHYHIPL,GABRB3,ILDR2,HIGD1B,GATM,PPARGC1A,BRD8,GLDC,TOX3,ZNF638,MAP7D2,GNG3,GPD2,PCLO,RFFL,SOX21,USP51,LRRCC1,LRRTM1,KTN1,PPM1L,MYO6,NOVA1,PAK3,PAX6,PIK3C2A,ANLN,SLC25A23,MASP1,ELOVL2,EML5,PTPRZ1,CCDC40,FEZF2,RBBP8,RFX3,RFX4,FBXW7,ZFP30,KIF21A,ARX,FHOD3,TET1,INTS9,LMO3,PRRC2C,SYN1,TCF7L2,NR2E1,LRRC8A,TPM3,PRMT8,STXBP4,SLAIN1,RBFOX3,ZNF23,TMEM163,CAB39L,WNK3,PDSS2" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 7.62E-18 3.89E-14 1.33E-16 1.21E-15 112 306 "NDRG2,SLITRK1,LTBP4,PPFIA2,APBB1,APOC1,ATP2B2,SNAI3-AS1,BCL7A,JAZF1,HAP1,VSTM2A,LONRF2,EVI5L,ADGRG1,LHX2,NRXN1,TJP2,IGLON5,ARHGEF6,NCOR2,AATK,CSF2RA,FEZ1,SIPA1L1,ST18,USP6NL,RASSF2,SCRN1,SPOCK2,CTIF,RUSC2,SHANK1,DTNA,EGFR,PLXNC1,ELAVL4,TMEM35A,SLC43A2,APC2,CHST15,FGF12,FOXG1,AFF2,DPYSL4,ATP6V1H,ATP2C1,TPPP3,NRG3,FYN,BRPF3,IQGAP2,SRRM4,PCDH17,PCDH11X,GPM6A,PCLO,GRIK2,NR3C1,MFSD2A,FAM107A,TOX2,FRMD3,IGFBPL1,NEGR1,BRINP3,PAXBP1,MAP2,SHC3,NRBP2,TAGLN3,NEXMIF,MYT1,NELL2,NFIA,SETD4,TMEM38A,POU6F1,MAPK10,GAL3ST4,EXD2,MEG3,RMI1,LRRTM4,LINC00461,SCG5,SLC1A3,SLC12A2,SMARCD3,SP4,ZBTB43,NPAS3,CLSTN2,STAU1,ZFR2,RHBDL3,ASTN2,SEMA4A,MCF2L,TMEM178B,CUX2,PSD3,TP53BP1,KCNE5,UCHL1,MEAF6,TSPAN11,LYPD6,STMN4,SNX14,GAN,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_100 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_100 FaceBase_RNAseq 7.92E-18 4.04E-14 1.37E-16 1.25E-15 54 100 "TTYH1,SLITRK1,SHTN1,ASCL1,FGF17,DIRAS1,HAP1,INA,ADGRG1,SRSF11,JAM2,LHX2,IGDCC3,RIMS2,ST18,SCRN1,JAKMIP2,ELAVL3,OLIG2,ADGRV1,CLVS1,FABP7,ZIC4,FOXG1,DLL3,ILDR2,SRRM4,TOX3,MAP7D2,STMN2,RNF165,SOX21,CELF3,TOX2,IGFBPL1,ATCAY,ZIC5,HES5,SHC3,SCG3,MYT1,NRCAM,FEZF2,RFX4,LINC00461,HSPA4L,ARX,SOX2,NR2E1,ZIC1,ZIC2,ZIC3,DPYSL5,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkG_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.24E-18 4.71E-14 1.60E-16 1.46E-15 34 46 "ASCL1,INA,SEPT7,NRXN1,NRXN2,CRMP1,DPP6,ELAVL4,EN2,FABP7,TAOK3,C1orf61,NSG2,NSG1,GAP43,DNER,GNG3,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,BEX5,NCAM1,NELL2,NNAT,RTN1,SCN2A,SCN3A,SNAP25,MYT1L,CELF4,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAa_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 9.72E-18 4.96E-14 1.68E-16 1.53E-15 46 77 "XKR4,SLITRK1,TMCC3,SYT13,ANK3,ASTN1,CALB1,RUNX1T1,INA,CHGA,CHGB,TENM4,EFNB3,TENM1,ELAVL3,TMEM35A,EPHA5,ACTL6B,NSG2,NSG1,B3GAT1,GAP43,GNAO1,GNG4,STMN2,CELF3,NEGR1,LSAMP,HS6ST3,NCAM1,KCNK10,PBX1,PXK,BSDC1,RTN1,SCN2A,SCN3B,PEG10,LMO3,SEPT3,ARHGEF12,VGF,CELF4,CADM2,SCG2,SLC17A6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.18E-17 6.04E-14 2.03E-16 1.85E-15 63 129 "ADCY8,SORCS1,DPP10,PPFIA2,CADPS,ASTN1,LDLRAD4,CDH10,DCLK1,SYNPR,COL9A1,COL9A3,FAM171B,CRYM,FEZ1,RIMS2,BRINP1,JAKMIP2,RAB39B,EBF1,EDIL3,EDN3,EDNRB,EYA1,WAC,FGF13,UBE2E3,SGIP1,GABRA1,SRRM4,PCDH11X,RAB40B,GPR17,GRM3,GRM7,HAS2,UBE2QL1,NEGR1,AGFG1,INSM1,KCNK2,RSPO2,MYH3,NAP1L2,NDP,CLDN11,CNTN3,GPR85,TRHDE,SLC6A15,ZMAT4,RPS20,SCN3A,FAM19A1,NTNG1,NPAS3,ELOVL4,ACSL6,PCDHB10,PCDHB7,HHIP,RPRM,LRP8" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k3 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.38E-17 7.04E-14 2.36E-16 2.15E-15 97 250 "ABAT,ADCY2,RNF150,SRPX,ARHGAP20,SYT13,DPP10,ANK2,TNRC6C,NOL4,ADGRB2,ADGRB3,CDK5R1,CACNA2D1,VSTM2A,RUNX1T1,DCLK1,LGI1,CNTN1,COL9A1,NTM,AK5,GRIN3A,DNM1,EBF1,EDIL3,EFNA3,EGFR,PLXNC1,NCALD,CDHR1,MRVI1,DACH2,GPR153,DKK3,MEGF10,GABRA1,GABRB3,NEK6,DNER,FREM1,GRIA1,GRIA4,GRM3,PTPRT,IRAK3,UBE2QL1,NEGR1,IL11RA,KCNA1,LSAMP,AFF1,MMP16,MN1,NCAM1,NTRK2,DDR2,CLDN11,PDE1C,PRRX1,SDK2,PTX3,RGS4,TTLL7,ZFHX4,LGI2,KIRREL1,MEG3,CSRNP3,LRFN5,SCN2A,ZFP2,TRA2B,ST8SIA1,RUFY2,SLC14A1,CXXC4,SORCS3,ZC3H13,KIF1B,CLSTN2,NEK4,SYT4,ADGRL3,ANO4,TBX15,CUX2,FAM189A1,PCDHB3,THBS4,ASXL3,RGMB,TTPA,TMEFF2,AMOT,FLRT2,NETO1" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k1_1000 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.40E-17 7.13E-14 2.38E-16 2.17E-15 50 89 "APLP1,ASCL1,INA,ARHGAP33,LHX2,COL9A1,CRMP1,CSNK1E,KIAA0408,GSDME,ELAVL4,FABP7,TUBB3,DPYSL4,DLL3,GAP43,TOX3,KIAA1958,GNG3,STMN2,BACH2,INSM1,TUBB2B,MAPT,TAGLN3,NEFM,NELL2,NEUROD1,GNG2,ZIK1,GAL3ST4,FIGN,RFX4,ZFHX4,ATAT1,LINC00461,HES6,SCG5,SNAP25,SOX2,SOX5,SOX11,GSE1,SYT11,TRIM2,CLASP1,ZIC1,ZIC3,PCBP4,VANGL2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.04E-17 1.04E-13 3.45E-16 3.15E-15 37 54 "ANK2,VAT1L,CADPS,NRP2,INA,DCLK1,RAB3C,RAB33A,FEZ1,PLXNA4,SCRN1,DLG2,ELAVL2,EYA1,FABP7,TUBB3,GAP43,IGSF5,GFRA2,GNAO1,STMN2,LIX1,KIF5C,L1CAM,SYTL4,NCAM1,NEFM,TMOD2,MAPK10,EML5,RTN1,SCG5,SNAP25,SCN3B,SYT11,CADM1,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb1_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 2.04E-17 1.04E-13 3.45E-16 3.15E-15 37 54 "ANK3,APLP1,CALB1,THSD7A,RUNX1T1,INA,DCC,EBF1,SEZ6L2,ELAVL3,NRN1,NSG2,NSG1,GAP43,DNER,GNG3,GPM6A,STMN2,IGFBPL1,KIF5C,L1CAM,MAP6,SCG3,TAGLN3,NCAM1,NEFM,PKIA,RTN1,SCN3A,BEX1,SYT4,TAC1,CNTN2,ZIC1,CELF4,SCG2,SLC17A6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.30E-17 1.17E-13 3.89E-16 3.54E-15 91 229 "PCDH10,SYT13,INSYN2B,CDK5R1,THSD7A,PTBP2,CH25H,RUNX1T1,CBLN1,CDH2,DCLK1,CDO1,CLGN,CRLF1,ZNF521,ANKRD44,NCOR1,ABCG1,ERC2,TOX,PITPNC1,MAGI2,DLX1,DRD1,EDNRA,EFNA3,TENM1,RGS17,EPHA5,EYA1,TMEM132C,FOXF2,SGIP1,NBEA,MEGF10,GABRA4,DNER,GLRB,GPR17,GRIA2,WIF1,FRMD3,BACH2,CELF5,IFI16,LRRTM3,MAP2,MYH3,DDR2,PAK3,PCDH8,GNG2,NLGN3,LRP12,PRRX1,EPB41L4B,PPP3CB,TMEM255A,FAT4,FIGN,ZFHX4,C12orf49,ROBO1,PRR5L,RPS20,SALL1,CSRNP3,ANKRD6,ZNF365,SLC1A3,LIMCH1,SOX11,KLHL7,TAC1,UNC5D,ADGRL3,TCF4,PCDHB15,PCDHB10,PCDHB3,ASXL3,KAT6B,TRPS1,SSBP2,FRRS1L,FLRT2,WIPF1,PCDH20,FMN2,KCNAB1,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.83E-17 1.44E-13 4.76E-16 4.33E-15 138 417 "SORCS1,USP31,TAOK1,PCDH10,DPP10,ANK3,APC,ASCL1,ADAM23,NRP2,CACNA1B,CACNA2D1,KALRN,CANX,RUNX1T1,INA,CDH10,CHGB,RAB33A,NRXN3,CNR1,COL9A1,MYRIP,SLC35F1,CRHBP,HAPLN1,TENM4,VCAN,ERC2,PLCXD3,SCRN1,BRINP1,JAKMIP2,ZNF804A,ZEB2,MFAP3L,NTM,ARNT2,GRIN3A,HS3ST4,CALN1,PDCD6IP,DYRK1A,HIPK3,EIF4G1,ELAVL2,ELAVL4,TUBB3,CORO2B,DLC1,ATP8A1,FOXF2,SGIP1,DPYSL4,CAMKK2,DACH2,DKK3,MEGF10,GABRA3,CHL1,GABRB1,IQGAP2,SYT17,DNER,GFRA1,GFRA2,PCDH17,PCDH11X,GRIA1,KLF12,BACH2,IFI16,INSM1,TUBB2B,KCNK2,KCNMA1,KCNQ2,KIF2A,KIF5C,MAP4,MAPT,RSPO2,NCAM2,NDP,NEFM,NFIA,NFIX,NNAT,NTRK2,OPRL1,CLDN11,PIRT,GPR85,DUSP26,NALCN,PIK3C2A,PRRX1,MBOAT7,KANSL1,MAPK8,MAPK10,PRPH,PTPRO,RET,REV3L,RGS4,ZFHX4,RTN1,SCN3A,NTNG1,ANKRD6,SLC15A2,SNAP25,SCN3B,SOX2,NPAS3,C11orf87,EPB41L3,MAPK8IP3,STX1A,DNMBP,CAMSAP2,ADGRL3,TBL1X,CUX2,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,TMEFF2,RPRM,UCHL1,FMN2,STMN4,STOX2,NUP214,MSRB3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.03E-17 1.55E-13 5.08E-16 4.63E-15 69 151 "SORCS1,FAM135A,VAT1L,CADPS,ASTN1,RNF182,ADAM23,LDLRAD4,CACNA1B,THSD7A,PTBP2,RUNX1T1,CDH2,CDH10,DCLK1,RCBTB2,SYNPR,CNR1,COL9A1,CRYM,JAKMIP2,EBF1,EDNRA,EFNA3,EPHA5,ETV1,EYA1,FGF13,UBE2E3,MEX3B,SGIP1,NBEA,DACH2,SRRM4,GRIA2,GRM7,RASSF8,BACH2,NEGR1,LRRTM3,KCNK2,KIF5C,MAP2,RSPO2,MYH3,NAP1L2,NEFM,NFIA,GPR85,GNG2,NALCN,PCDH18,HMGCLL1,TRHDE,PRRX1,FAT3,ZMAT4,SCN3A,FAM19A1,NTNG1,ANKRD6,NPAS3,ADGRL3,PCDHB10,PCDHB3,RPRM,FRRS1L,FMN2,LRP8" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.09E-17 1.58E-13 5.17E-16 4.71E-15 44 73 "SYT13,ANK3,APBB1,APP,KIF1A,GPC2,SEPT7,ELAVL3,NSG2,NSG1,PNMA2,GABRB3,GAP43,DNER,GPM6A,STMN2,PTPRT,CELF3,UBE2QL1,MAP6,CD200,SAMD14,MYO5A,BEX5,FXYD6,NCAM1,GNG2,RAB3A,RGS4,RTN1,SCN3A,MRAS,RIMS1,SNAP25,SCN3B,PEG10,SYP,SYT4,VGF,CELF4,REEP1,STMN4,SCG2,CBLN2" Coexpression Atlas PCBC_ECTO_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 3.58E-17 1.83E-13 5.97E-16 5.44E-15 157 499 "VAT1L,ASTN1,KIF1A,CA4,CAMK2A,CCK,CDH8,CDH18,LGI1,SYNPR,LHX2,IGLON5,COL9A1,GAL3ST1,TCEAL2,NRG2,IGDCC3,HAPLN1,NCAN,CNTNAP2,PLCXD3,CTNND2,RIMS3,DGKG,LYPD1,SNAP91,CDON,FAM57B,EFNA2,ELAVL2,ELAVL4,EMX2,TMEM74,ADGRV1,CLVS1,FABP7,ZIC4,C1orf61,ATP13A4,B3GAT1,PHYHIPL,ILDR2,SALL3,IP6K3,SYT17,GPR162,GLDC,TOX3,PCDH11X,AIFM3,PRUNE2,GPM6A,DIPK1C,LPAR4,CECR2,GRM3,SOX21,GUCY1B1,CELF3,UBE2QL1,IGSF21,NXPH3,HAPLN2,IGFBPL1,CELF5,BTBD17,PLD5,HES5,LIX1,INSM1,ZNF385B,KCNA1,OLFM3,KCNQ2,KIF5C,LRRC4B,CLEC18A,MAP6,SESN3,BCO1,SCG3,TAGLN3,DDX25,MYO7A,TCEAL5,NELL2,NHLH1,NPY,IGSF11,KCNK10,PAX6,PRTG,ENPP2,PLP1,HMGCLL1,SDK2,NECAB2,MAGEL2,POU3F2,NKAIN4,RAB39A,LAMA1,ELOVL2,PTPRD,STRC,TMEM255A,FEZF2,RFX4,RLBP1,ZFHX4,KLHDC8A,HUNK,FAM182A,SLC30A10,TMEM200C,SCG5,ARX,SLC1A6,PKNOX2,SLCO1A2,DMRTC1,RIMS1,SOX1,SOX3,SOX15,LHFPL4,LMO3,CLSTN2,STOX1,SMOC1,SOX21-AS1,ZFR2,TAC1,UNC5D,PCDHA6,PCDHA3,PCDHA2,NR2E1,RIMBP2,PRMT8,CA14,TTPA,CLEC2L,RBFOX3,ZIC1,KCNT2,EMX2OS,CRB2,MKRN3,DPYSL5,LAMP5,CA10,CADM2,GAL3ST3,DOCK8,SLC4A10,JPH3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.24E-17 2.67E-13 8.70E-16 7.93E-15 37 55 "ANK2,ADAM23,INA,RAB3C,NRXN1,FAM171B,ERC2,RIMS2,JAKMIP2,ZNF804A,SPOCK3,DLG2,RAB39B,ELAVL2,ELAVL4,FABP7,SGIP1,PHYHIPL,GABRB3,GNAO1,GRIA2,KIF5C,SCG3,NAP1L2,NCAM2,NEFM,NOVA1,STK32A,EML5,PTPRZ1,RGS7,KIF21A,SNAP25,CUX2,CADM1,FSTL5,SCG2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.40E-17 3.77E-13 1.23E-15 1.12E-14 223 800 "EMILIN3,NDRG2,ADCY8,ADD1,ADD3,PNMA8B,WDR35,TAOK1,C1QTNF3,SPARCL1,SRPX,ARHGAP20,PCDH10,LTBP4,LCORL,PKP4,PTCH2,DDX3Y,ATP1A2,ATP2B1,DOCK11,BACH1,ADGRB3,JAZF1,SGCE,IL33,BTRC,VSTM2A,RUNX1T1,LDB2,DCLK1,ZNF445,SRSF11,CHM,SLIT2,KMT2C,NMT2,COL4A5,ABI3BP,CP,RBM39,CRYBB1,CSF1R,FEZ1,DZIP3,PLCXD3,PUM1,FGFR1OP2,TCAF1,RIPOR2,AIF1L,GIT2,ZEB2,MFAP3L,ZC3H11A,GSDME,CHRDL1,CDON,ABCC9,EDNRA,SEMA3D,APH1A,MBNL2,EIF4G1,ELN,CALCRL,EMX2,ENO2,EPB41L2,LRRC17,SRRM1,ETV1,TMEM132C,SCML2,EFEMP1,FCGRT,KIAA1109,FGF1,MEX3B,SEMA6C,ANKFY1,SMC2,APOPT1,FUT9,GABRA4,GABRB1,ILDR2,GAD1,SRCAP,CSDC2,GGTA1P,TNRC6A,GLUL,HTATSF1,CNDP1,GPM6A,LPAR4,STMN2,PARD3B,GRIK1,GRM7,CIT,KIF3A,KAT7,RASSF8,HAS2,KLF12,MIER3,IGF1,IGFBP1,ZNF385B,JAK1,KCND3,LAMA2,HECTD2,MAOB,MAP4,MATN2,CHIC1,MEF2C,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,NRBP2,NASP,NFIA,NFIX,CNOT4,NTRK2,NTRK3,OCRL,PCDH9,PCSK5,PDGFRA,PDPK1,PENK,OLA1,NALCN,PIK3R1,PLCL1,PLEC,FXYD1,PLTP,RC3H2,PRRX1,FAT3,SH3KBP1,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,VEPH1,RNASEL,LGI2,TMLHE,MRAP2,MEG3,ATXN1,ATXN2,FNIP1,SFPQ,TRA2B,ARX,CHD9,WDR37,SLC12A2,SCMH1,TET1,ARFGAP1,ZKSCAN3,RCOR3,TNIK,ZCCHC24,ZC3H13,KIF1B,RBM26,TROVE2,PRRC2C,SYNE2,ANKRD12,TBL1X,KLHL4,TCF7L2,WASHC4,CLASP1,PCDHB9,OBSL1,AHCYL2,HIF3A,HHIP,CBX5,ASXL3,R3HDM1,TNNT1,TNS1,RBFOX2,RASD2,TPM1,NR2C2,TRIO,TRPS1,TSC1,SSBP2,UBE3A,UBTF,FLRT2,VLDLR,PCDH20,ZNF711,ZBTB16,PMEPA1,ADAMTS9,NAV2,SNX27,FIP1L1,RGS7BP,JMJD1C,GAN,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 7.64E-17 3.89E-13 1.26E-15 1.15E-14 101 271 "SLITRK1,RNF157,LTBP4,GPRASP2,PPFIA2,PHYHD1,USP37,ASTN1,ADAM23,DIRAS1,VSTM2A,CDK11B,LONRF2,CDH8,ADGRG1,KIAA1549L,NRXN1,IGDCC3,CREB5,AATK,FEZ1,PHF14,ST18,NOS1AP,HDAC9,TOX,SCRN1,JAKMIP2,RUSC2,DDX46,DLX1,DMD,SHANK1,CASP8AP2,DTNA,MAMLD1,TMEM35A,EPB41,EPB41L1,EPHA5,APC2,NSRP1,CHST15,AFF2,DPYSL4,ZCCHC17,B3GAT1,NRG3,PPARGC1A,MAP7D2,MFSD2A,USP51,NEGR1,BRINP3,CREG2,KIF5C,TM6SF1,TAGLN3,NASP,NCAM2,NELL2,NFIA,ODF2,PCDH9,PDE1A,SEMA5B,TMEM38A,POU6F1,DIRAS2,MDGA2,ENOX1,RBBP8,MEG3,STX1B,ATXN1,LRRTM4,FHOD3,NLGN1,CCDC88A,SMARCD3,SOX11,UHRF1BP1L,NPAS3,CLSTN2,RHBDL3,SEMA4A,TMEM178B,CUX2,PSD3,FLRT1,USP1,TSPAN11,FMN2,LYPD6,ZNF184,SPIRE1,LRP8,TMEM163,KLHDC1,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 8.72E-17 4.45E-13 1.44E-15 1.31E-14 52 98 "PLEKHH1,KIAA1211,EPB41L5,KIF1A,PROM1,CDH2,CHN2,LHX2,KIAA1549L,NIPBL,IGDCC3,PLCH2,CTNND2,RIMS2,ELAVL2,ELAVL4,EMX2,EPB41,MED12L,OLFM1,PHYHIPL,ILDR2,KIAA1841,GLDC,MAP7D2,GNG3,PCLO,STMN2,SOX21,IGFBPL1,INSM1,KIF5C,SCG3,PAX6,NECAB2,SLC22A23,ELOVL2,EML5,FEZF2,RBBP8,HSPA4L,KIF21A,SOX2,SP4,FGD4,SYNE2,WWC1,CCDC173,NR2E1,TRO,SLAIN1,FZD3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.10E-16 5.60E-13 1.80E-15 1.64E-14 80 193 "SORCS1,RNF150,ANK2,VAT1L,CADPS,ASTN1,RNF182,CDK5R1,LDLRAD4,CACNA1B,THSD7A,RUNX1T1,CDH2,DCLK1,CLGN,SYNPR,CNR1,AKAP7,ZNF521,SLC35F1,FAM171B,ABCG1,CRYM,TENM4,ERC2,RIMS2,SCRN1,PITPNC1,JAKMIP2,ARNT2,DRD1,EDNRA,EFNA3,TENM1,EPHA5,EYA1,TMEM132C,UBE2E3,SGIP1,NBEA,DACH2,MEGF10,GABRA1,SRRM4,PPARGC1A,GLI2,GPR17,GRIA2,GRM3,BACH2,NEGR1,CELF5,LRRTM3,KCNK2,KIF5C,RSPO2,NAP1L2,NDP,GPR85,GNG2,PCDH18,HMGCLL1,TRHDE,PRRX1,FIGN,ROBO1,SCN3A,FAM19A1,DZIP1,ANKRD6,ZNF365,NPAS3,ELOVL4,CAMTA1,PCDHB10,PCDHB3,ASXL3,RPRM,FMN2,LRP8" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K5 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.57E-16 8.01E-13 2.57E-15 2.34E-14 83 205 "SLITRK1,PLEKHH1,PTCHD1,ZNF608,SHROOM2,PTCH2,FGF17,HAP1,ADGRG1,NRXN3,NRXN2,TJP2,NECTIN3,CRMP1,NCAN,SLITRK5,RIMS2,NOS1AP,MYEF2,ELMO1,SRGAP3,KBTBD11,DTNA,EDNRB,ELAVL2,CERCAM,EPHB1,EXTL2,ADGRV1,REEP2,FABP7,TUBB3,SPSB4,FOXM1,DLL3,GABRB3,AHCYL1,SRRM4,TOX3,GPR19,TUBA1C,STMN2,GRIK2,GRIK3,RNF165,CELF3,TOX2,FRMD5,DDX19B,CELF5,ATCAY,ZIC5,HES5,AFDN,NNAT,NRCAM,NLGN3,MAPK7,MAPK10,PROX1,GSTCD,RTKN,RTN1,HSPA4L,SCG5,SOX2,KDM3A,SP2,SYP,TACC1,MCF2L,WWC1,WSCD1,ACSL6,SLAIN1,MGAT5B,ZIC1,ZIC3,ZNF24,DPYSL5,FZD3,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.67E-16 8.51E-13 2.72E-15 2.48E-14 177 595 "DPF1,CLK4,NCKAP5,ARID1A,ADCYAP1R1,PLEKHH1,KIAA1211,PHF12,PKP4,APC,EPB41L5,ARHGAP5,NUMB,ATP1A3,KIF1A,BBS2,PROM1,ARHGEF7,FUBP1,CANX,KRIT1,SLC16A4,CDK11B,CDH2,CDH8,ZNF445,CHN2,JAM2,LHX2,ZFYVE9,NRXN2,COG1,QKI,HECTD1,IGDCC3,SLC35F1,CLOCK,MICAL2,SIPA1L1,CTNND2,RIMS2,EDRF1,TBC1D5,MATR3,KIAA0586,JAKMIP2,CEP170,RAB39B,DMTF1,MAMLD1,DYRK1A,DNM1L,KLHL5,PLXNC1,ELAVL2,ELAVL4,MTSS1L,SEZ6,SRRM1,RTN3,NSRP1,WAC,PRKAG2,FUT9,B3GAT1,OGA,PHYHIPL,STAG2,GABRB3,CAB39,ILDR2,C15orf41,KIAA1841,SRCAP,ARFIP1,PPARGC1A,GLDC,TNRC6A,MAP7D2,GNG3,GOLGB1,TDRKH,PCLO,DIDO1,SOX21,HMGB1,USP51,HSF2,INSM1,TUBB2B,KIF5C,LIMS1,LSAMP,MBP,PPM1L,SAMD5,BCO1,SCG3,NEK1,NELL2,NOVA1,SETD4,GPR137C,PAK3,PCMT1,SEMA5B,ING3,CEP41,ELOVL2,EML5,PTPRZ1,NKAIN1,ARID4A,ZYG11B,RFX4,SETD5,RPE,CLIP1,SCP2,ZFP2,SOX6,CASC3,TRA2B,KIF21A,PPM1E,ARX,CHD9,FNDC3A,ST8SIA1,SLC1A2,EPN2,SEPHS1,SLC12A2,CDK5RAP2,SON,SPATA7,SP4,ZNF423,NPAS3,MPRIP,STXBP1,ACSBG1,ZC3H4,SYNE2,DNAJC9,SYN1,TAF6,TAF9,FAM208A,TBL1X,TCEA1,ZEB1,ARHGEF12,SIRT1,ZFP91,NR2E1,TMPO,TRIO,TRO,FAM181B,MEAF6,RBFOX3,WNT7A,ZNF711,KCNT2,ZFP41,CELF4,ZNF142,REEP1,WNK1,MAP3K12,PRDM2,WNK3,FAM13C,KAT6A,HNRNPA3,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl Top 40 GSE76381_iPSMoleculeCountsPMLog2 1.67E-16 8.53E-13 2.72E-15 2.48E-14 49 90 "SYT13,ANK3,VAT1L,RUNX1T1,LDB2,SEPT7,DCLK1,CHGB,NRXN1,PREPL,NCOR1,ARHGAP32,EARS2,CEP170,SEZ6L2,ELAVL3,NSG2,NSG1,B3GAT1,GAP43,GNG3,GPM6A,CCDC184,PCLO,STMN2,CELF3,SCRG1,CELF5,LSAMP,NCAM1,PAK3,GNG2,TMOD2,PPP2R2B,PTN,RALGDS,ZFHX4,RTN1,SNAP25,SCN3B,PEG10,SEPT3,SYT4,TUBB2A,VGF,TRIM9,CELF4,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbM_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.83E-16 9.33E-13 2.96E-15 2.70E-14 38 59 "THSD7A,INA,ADGRG1,NCAN,ST18,DCC,EBF1,ELAVL2,ELAVL3,ELAVL4,EN2,EPB41,NRN1,TUBB3,GAP43,GPM6A,STMN2,GRIA2,GRIK2,INSM1,SCG3,TAGLN3,NCAM1,NEUROD1,NHLH1,NNAT,SCHIP1,RTN1,SCN3A,SEPT3,CNTN2,ZEB1,TCF12,RGMB,FNDC5,TSPAN11,CELF4,TMEM163" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.72E-16 1.39E-12 4.39E-15 4.00E-14 228 832 "SDE2,ABAT,FMNL2,ADCY2,KLHL13,NR0B1,WDR35,ADGRF5,SPARCL1,SEMA6A,ARHGAP20,LCORL,CACHD1,LRRC4C,CDC14B,PPP4R4,CASK,ZSCAN18,TMEM108,ATP2B1,ATP2B3,RNF182,BACH1,MPDZ,CACNA1G,WASF1,MYRF,CACNA2D1,CALB1,KALRN,PTBP2,RUNX1T1,CBLN1,LDB2,AP4M1,CDH2,CDH10,DCLK1,LARGE1,MAGI1,SLIT2,CNTFR,AKAP7,ZNF521,HAPLN1,CLIP3,TENM4,ATRNL1,VCAN,PLXNA4,FAM169A,BOC,DOCK4,DAPK1,ARMCX2,ZEB2,HEPH,MAGI2,SV2A,SRGAP3,DNM1,CDON,DRP2,E2F5,EDNRA,KLHL5,PLXNC1,TMEM35A,EMX2,PLEKHO1,NRN1,F3,ABCA8,FAM198B,FABP7,EFEMP1,MEX3B,CAP2,IP6K2,FLNC,AFF2,NOP56,ZMAT1,GABRA4,GAP43,FAXC,FREM1,GHR,COPS8,GLI2,PCDH11X,ADGRA3,GPM6B,B4GALNT4,LPAR4,GPR37,GUCY1A2,ADAMTS6,GUCY1A1,GUCY1B1,HAS2,HMGB1,TCEAL6,HSF2,HSPA1L,NKD1,KCND2,KLHL23,LIFR,MATN2,CHIC1,MEIS1,MEIS2,KITLG,POC1B,MMP16,SESN3,CCDC80,MTR,MYBPC1,MYO9A,TCEAL5,NASP,NCAM1,ZC3H12B,NEFM,NFIA,NNAT,NME4,NOVA1,DDR2,PBX1,PDE1A,PDE3A,PDGFRA,GNG2,CDK14,SERPINI1,PIK3R1,PCDH18,PRRX1,FAT3,SH3KBP1,PPP3CC,SYTL2,LAMA1,MDGA2,CNTLN,PTN,ZIK1,PTPN13,PTX3,TMEM255A,FAT4,ZCWPW1,RIC8B,RNASEL,ZFHX4,ROBO1,ROBO2,TMEM206,ARMH4,LGR4,MEG3,HUNK,ZNF354C,CCDC112,SATB1,CSRNP3,SCN2A,RASA3,DOCK10,ST6GAL1,ST8SIA1,DZIP1,SLC1A3,SLC4A3,PKNOX2,ZNF334,SCMH1,ATF7IP,SMARCE1,SNCA,PALLD,PDZRN3,ZCCHC24,SOX11,KDM3A,CAND2,UHRF1BP1L,PEG10,SMOC1,ST5,KLHL7,ADGRL3,KLHL4,CUX2,TCF12,SZT2,PSD3,OBSL1,TEX15,TEK,DNAH7,ZFPM2,TGFBR3,ACTR6,ASXL3,DAAM2,KAT6B,TNNT1,TPM1,STXBP4,TRPS1,FNDC5,SSBP2,TMEFF2,FLRT2,PLEKHH2,VLDLR,PCDH20,ZFP37,ZNF711,LYPD6,ZNF184,WNK3,DPF3,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k1 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.26E-16 1.66E-12 5.24E-15 4.77E-14 56 113 "SLITRK1,SORCS1,ANK2,VAT1L,ADGRB3,DCLK1,CHGB,CNTN1,AKAP6,COL9A1,COL9A3,MYRIP,CRMP1,NRSN1,SCRN1,SNAP91,GRIN3A,EBF1,ST8SIA3,ELAVL4,FABP7,PNMA2,GABRA1,GAP43,CPLX1,GFRA2,STMN2,GRM7,UBE2QL1,NEGR1,AGFG1,IGF1,INSM1,KCNK2,MAP4,MAPT,MN1,NEFM,NFIA,CLDN11,CNTN3,GPR85,PKIA,MAPK10,DIRAS2,PRPH,RGS4,RTN1,S100B,SPHKAP,SNAP25,SCN3B,C11orf87,SYT1,HIF3A,NETO1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.37E-16 1.72E-12 5.39E-15 4.91E-14 75 178 "USP31,TAOK1,DPP10,SLC7A14,CADPS,ASTN1,NRP2,CACNA1B,CACNA2D1,INA,CDH10,CHGB,CNR1,CNTN1,MYRIP,VCAN,PLCXD3,DNAJC6,MFAP3L,GRIN3A,ELAVL2,ELAVL4,EPHA5,EYA1,DLC1,FOXF2,SGIP1,DACH2,CHL1,DNER,GFRA1,PCDH11X,GPR22,STMN2,GRM7,FAM19A2,IFI16,KIF5C,MAP4,MMP16,RSPO2,NAP1L2,NCAM2,NEFM,NFIA,NTRK2,CLDN11,SLC10A4,GPR85,NALCN,PRRX1,FAT3,MAPK10,PRPH,RET,RGS4,ZFHX4,RTN1,CSRNP3,SCN3A,ST8SIA1,NAPB,SNAP25,SCN3B,SOX2,SOX5,NPAS3,C11orf87,CUX2,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,RPRM" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.37E-16 1.72E-12 5.39E-15 4.91E-14 133 407 "ADD1,ADD3,PNMA8B,TAOK1,ARHGAP20,PCDH10,LTBP4,LCORL,PKP4,DDX3Y,ATP2B1,DOCK11,BACH1,SGCE,IL33,VSTM2A,RUNX1T1,LDB2,DCLK1,ZNF445,SRSF11,CHM,SLIT2,PLAA,NMT2,COL4A5,RBM39,PUM1,FGFR1OP2,TCAF1,AIF1L,ZEB2,ZC3H11A,CDON,EDNRA,EIF4G1,EPB41L2,LRRC17,SRRM1,TMEM132C,SCML2,MEX3B,ANKFY1,SMC2,APOPT1,GABRB1,ILDR2,GAD1,SRCAP,CSDC2,PCDH11X,LPAR4,STMN2,GRIK1,GRM7,KIF3A,RASSF8,HAS2,KLF12,KCND3,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MYBPC1,NASP,NFIA,NFIX,CNOT4,PCDH9,PDPK1,PENK,NALCN,PIK3R1,PLTP,RC3H2,PRRX1,FAT3,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,LGI2,TMLHE,ROBO2,MEG3,NCBP3,ATXN2,FNIP1,SFPQ,TRA2B,ARX,CHD9,WDR37,SCMH1,TET1,ZKSCAN3,SNCA,ZCCHC24,ZC3H13,RBM26,TROVE2,PRRC2C,SYNE2,KLHL4,CLASP1,PCDHB9,OBSL1,AHCYL2,HIF3A,CBX5,ASXL3,R3HDM1,TNS1,TPM1,NR2C2,TRPS1,SSBP2,UBE3A,FLRT2,VLDLR,PCDH20,PMEPA1,ADAMTS9,NAV2,SNX27,FIP1L1,GAN" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.79E-16 1.93E-12 6.04E-15 5.50E-14 139 433 "TTYH1,KDM5D,GRAMD1B,ADORA1,MTA3,HECW2,NR0B1,BCAR3,AMH,SEMA7A,USP28,GAS7,APOC1,SHTN1,LGR5,CDC14B,PPP4R4,ARHGDIG,CADPS,DDX3Y,ATP2B3,ALDH7A1,BCHE,RGS11,DST,ST3GAL5,SYNJ2,CACNA2D2,ADGRG1,JAM2,CLU,CLTB,FADS2,MAGED1,PPP1R16B,TOX,SCRN1,JAKMIP2,ELMO1,PLPPR4,SRGAP3,CPEB2,RCAN1,GNE,DTNA,DTNB,MAMLD1,EDN1,SIDT2,MRO,PLXNC1,SORBS3,CERCAM,EPS8,ERBB2,ERBB4,REEP2,FAM198B,ACSL4,PTK2B,TUBB3,ATP8A1,FGF13,SEMA6C,AFF2,CAMKK2,FYN,BRPF3,IQGAP2,GATM,PPARGC1A,ADGRA3,GPM6B,GPR37,PADI2,HSD17B1,SHISA6,KCNH1,KLHL23,SYTL4,NCOA7,MEF2C,KITLG,MOV10,MSI1,NRBP2,CTNNA3,MYO7A,NEXMIF,CLDN11,PAK3,PGAM2,SERPINE2,SCHIP1,RASGEF1B,EPDR1,MASP1,LAMA1,PTPRE,SH3TC2,DUSP15,NUDT11,ROBO1,TMEM206,RPS6KA2,SOX8,SOX6,MRAS,KIF21A,SH3GL2,DOCK10,ST6GAL1,SLC6A8,EFHD1,TNIK,UHRF1BP1L,SPP1,TSPYL2,SMOC1,ST5,ADHFE1,SYNE2,TACC1,SIN3B,OBSL1,ZFPM2,THRA,TIAM1,DAAM2,BEX4,TPD52,TRPC3,FNDC5,TST,SGK3,SLC38A1,ADAMTS9,WNK3,NHSL1" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.47E-16 2.28E-12 7.11E-15 6.48E-14 136 421 "ADCY2,GALNT13,SORCS1,RNF150,PCDH19,C1QTNF3,ALCAM,ABCD2,FAM135A,DPP10,LRCH2,APAF1,TNRC6C,CASK,RNF182,DOCK11,IL33,CACNA2D1,THSD7A,RUNX1T1,LDB2,MYOM2,CDC27,CDH2,NSL1,NCOR1,LRIG1,CTH,PYGO1,RASSF2,NTM,CCDC3,CALN1,EBF1,EDIL3,EDN3,SEMA3D,TMTC1,EFNA3,ABI2,ADGRV1,MRVI1,ATP8A1,SLC9B2,UBE2E3,SYNCRIP,SLC37A3,GABRA1,CHL1,IQGAP2,DNER,FREM1,GGT5,KIRREL3,BRD8,GLRB,PCDH11X,RAB40B,GPR12,GRIA1,GRIA4,CACFD1,GRM3,GUCY1B1,WIF1,RASSF8,HAS2,KLF12,NEGR1,MSL1,IFI16,ITGAV,KCND2,LSAMP,MEF2C,MMP16,MYO5A,NOVA1,DDR2,PBX1,PCDH8,PDE4B,GPR85,PENK,ANLN,PLCL1,SH3KBP1,RELN,CNTLN,FAT4,GAL3ST4,CRTAC1,FIGN,KIRREL1,LRRK2,LGR4,CCDC112,SALL1,CSRNP3,SCN3A,LRRTM4,SCN7A,FAM19A1,DOCK10,NTNG1,ST8SIA1,DZIP1,WDR37,SLCO1A2,CXXC4,ZHX3,ITPRID2,NEK4,RHBDL3,ADGRL3,ANO4,PCDHB9,PCDHB3,ZFPM2,ASXL3,TLR4,ZFP91,ERCC6L2,TRO,SSBP2,TTPA,CADM1,AMOT,PCDH20,MKRN3,LYPD6,PLSCR4,FAM13C,CERS6,NETO2,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAb_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.12E-16 2.61E-12 8.11E-15 7.39E-14 44 77 "TMCC3,SYT13,ANK3,APP,ZSCAN18,CALB1,INA,CHGB,AKAP6,JAKMIP2,ELAVL2,ELAVL3,TMEM35A,STARD3NL,CACNG2,EVL,NSG2,NSG1,FYN,JPH4,GAP43,GNAO1,STMN2,KIF3A,CELF3,NEGR1,CELF5,LSAMP,KITLG,NCAM1,NRCAM,PAK3,PBX1,SNX10,FAT3,ZFHX4,RTN1,SCN2A,SCN3B,PEG10,SEPT3,VGF,CELF4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb2_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 5.35E-16 2.73E-12 8.44E-15 7.70E-14 39 63 "APLP1,THSD7A,KALRN,INA,ADGRG1,DCC,EBF1,SEZ6L2,ELAVL3,NRN1,MEX3B,DLL3,B3GAT1,GAP43,DNER,GNG3,STMN2,IGFBPL1,INSM1,KIF5C,MAP6,MEIS2,SCG3,TAGLN3,NCAM1,NEFM,NHLH1,POU3F2,RALGDS,RTN1,NFASC,GSE1,SYT4,TAC1,CNTN2,ZEB1,FNDC5,ZIC1,SLC17A6" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.01E-16 3.06E-12 9.46E-15 8.62E-14 226 828 "ACTN1,KDM5D,FMNL2,ADCY2,RNF157,ADCYAP1R1,KLHL13,NR0B1,WDR35,ADGRF5,SPARCL1,SEMA6A,ARHGAP20,GPAM,CACHD1,LRRC4C,PPP4R4,CASK,DDX3Y,ATP2B1,ATP2B3,MPDZ,BLM,CACNA1G,WASF1,MYRF,CACNA2D1,CALB1,KALRN,RUNX1T1,CBLN1,LDB2,CDH2,CDH10,DCLK1,LARGE1,MAGI1,SLIT2,CNTFR,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,DCT,ZEB2,HEPH,MAGI2,ALKBH8,SV2A,SRGAP3,EXOG,DNM1,CASP8AP2,DRP2,E2F5,TSPAN5,EDNRA,SEMA3D,MRO,PLXNC1,SORBS3,EMX2,PLEKHO1,LRRC17,MTSS1L,ERBB2,NRN1,ABCA8,FAM198B,FABP7,PTK2B,EFEMP1,CEP78,FGFR1,MEX3B,CAP2,FLNC,AFF2,ST6GALNAC3,NSG1,ZMAT1,GABRA4,DENND2A,GAP43,IGSF5,FREM1,GHR,PPARGC1A,COPS8,GLI2,GLUL,PCDH11X,ADGRA3,GPM6B,B4GALNT4,GPR37,BVES,GUCY1A2,GUCY1A1,GUCY1B1,ARHGAP19,HMGB1,TCEAL6,HSF2,SHISA6,NKD1,KCND2,KLHL23,LIFR,MATN2,MEIS1,MEIS2,KITLG,AFF1,MMP16,CCDC80,MTR,MYBPC1,MYO9A,NCAM1,NEFM,NFIA,NNAT,NME4,PDE1A,PDE3A,PDGFRA,CDK14,SERPINI1,ANLN,PIK3R1,PCDH18,PRRX1,FAT3,SH3KBP1,PPP2R5C,PPP3CC,CEP41,PRKCB,SYTL2,LAMA1,PTCH1,PTN,ZIK1,PTPN13,PTPRD,PTPRG,PTX3,TMEM255A,ZCWPW1,REV3L,ZFHX4,ROBO1,ROBO2,TMEM206,GLDN,RPS6KA2,LGR4,HUNK,ZNF354C,SEMA6D,SATB1,CSRNP3,SCN2A,SOX6,ZNF821,MRAS,RASA3,DOCK10,ST6GAL1,ST8SIA1,DZIP1,PKNOX2,ARFGAP1,SMARCE1,FAIM2,PALLD,ZCCHC24,KDM3A,CAND2,UHRF1BP1L,SPP1,PEG10,SMOC1,ST5,RGL1,SULF2,SEPT3,KLHL7,SYNE2,ARHGEF9,NUDT10,ADGRL3,KLHL4,PSD3,OBSL1,TEX15,DNAH7,ZFPM2,TGFBR3,HEY1,ACTR6,ASXL3,DAAM2,TNNT1,TPM1,STXBP4,TRPS1,TMEFF2,AMOT,FLRT2,PLEKHH2,PCDH20,ZNF711,LYPD6,ADAMTS9,WNK3,DPF3,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Subtype_hNbML5_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.50E-16 3.31E-12 1.02E-14 9.29E-14 40 66 "ASIC1,KIDINS220,PPFIA2,THSD7A,RUNX1T1,INA,DCC,EBF1,KMT5B,ELAVL2,ELAVL3,ELAVL4,EMX2,NRN1,TUBB3,NSG2,GAD1,GAD2,GAP43,DNER,GNAO1,GPM6A,STMN2,GRIA2,CELF5,INSM1,MEIS2,TAGLN3,NCAM1,NNAT,RTN1,SCN3A,MYT1L,KIF21B,SEPT3,SYT1,TAL1,RBFOX2,NDRG4,CELF4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkH_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.25E-16 3.70E-12 1.13E-14 1.03E-13 37 58 "ANK3,PPFIA2,ASCL1,CDK5R1,RUNX1T1,INA,SEPT7,NRXN1,NRXN2,CRMP1,ELAVL2,ELAVL3,ELAVL4,EN2,FABP7,TUBB3,TAOK3,C1orf61,NSG2,GAP43,DNER,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,NEGR1,NEXMIF,NCAM1,LRRN3,REV3L,RTN1,SCN2A,SCN3A,MYT1L,CELF4,REEP1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.66E-16 4.42E-12 1.35E-14 1.23E-13 221 807 "RALGAPA1,EMILIN3,ADCY5,SORCS1,USP31,BEND6,SORCS2,SEMA6A,PCDH10,FAM135A,OGT,DPP10,ANK3,APC,TNRC6C,SEMA4G,CASK,CADPS,ASTN1,ADAM23,NRP2,BMP7,CDK5R1,DST,WASF1,LDLRAD4,CACNA1B,CACNA1D,CACNA2D1,THSD7A,KALRN,CANX,RUNX1T1,MYOM2,CDH10,CLCN3,COL9A1,SLC35F1,FAM171B,CRMP1,ANKRD44,CLIP3,SNCAIP,TENM4,FEZ1,SUSD5,PLCH2,SIPA1L1,VCAN,ERC2,CTNND2,PYGO1,HDAC4,TOX,KIF26A,TM9SF4,BRINP1,JAKMIP2,ELMO1,AK5,ARNT2,GRIN3A,DNM1,HS3ST4,CALN1,DNM2,DRP2,EDNRA,EDNRB,HIPK3,SEMA3D,CACNG7,EGFR,EPB41,EPHA5,EFS,SPEG,ETV1,EYA1,MRVI1,NRN1,TMEM132C,CORO2B,EFEMP1,KIAA1109,CAMSAP1,CAP2,FOXF2,SGIP1,DPYSL4,ZBED3,PRELID3A,CELF1,DACH2,TVP23A,MEGF11,DKK3,MEGF10,GABRA1,GABRA3,CHL1,IQGAP2,SYT17,GFRA1,GFRA2,PCDH17,GHR,PPARGC1A,GLI2,GLRB,PCDH11X,KIAA1958,FERMT2,PRRC2B,B4GALNT4,GRIA2,GRM3,GUCY1A1,GUCY1B1,KLF12,BACH2,MSL1,IFI16,IL6ST,KCND3,KIF5C,ASPRV1,MARK1,IL17D,CHIC1,PPM1L,MKLN1,MN1,MSI1,JAKMIP3,RSPO2,SAMD14,MYH3,MYH7,NCAM2,NDP,NEFM,NFIA,NFIX,CLDN11,ZNF827,PDE3A,PDGFRA,GPR85,SSH1,PIK3C2A,PCDH18,TRHDE,PRRX1,FAT3,KANSL1,NKAIN4,MAPK8,PTCH1,PTPRG,FAT4,ZYG11B,REV3L,ZFHX4,ROBO1,ARMH4,RYR3,SALL1,SCN3A,HES6,TNFRSF19,ZFP2,NTNG1,BTBD3,SLC8A3,SLC15A2,IFT122,SNAP25,PDZD2,SOX2,ZHX3,CAND2,MYCBP2,KIF1B,NPAS3,C11orf87,CLASP2,SMOC1,EPB41L3,RGL1,ARHGEF9,MTCL1,CAMTA1,CAMSAP2,ADGRL3,VWC2,CUX2,SZT2,FAM189A1,PCDHB7,PCDHB3,HIF3A,HHIP,THBS4,TIAM1,ERCC6L2,TNNT1,RBFOX2,RGMB,SYNPO2,TRIO,TRPS1,RPRM,FLRT2,FMN2,TCEAL7,STOX2,FAM13C,NUP214,MSRB3,ST8SIA2" Coexpression Atlas Arv_EB-LF_500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 8.67E-16 4.42E-12 1.35E-14 1.23E-13 95 256 "KCTD16,DPP10,MYRF,CALB2,LGI1,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,ATRNL1,NCAN,DCT,SNAP91,DPP6,EDIL3,EDN3,ELAVL3,ELAVL4,EN2,EPHA5,FABP7,TMEM132C,ZIC4,ACTL6B,HPCAL4,C1orf61,NSG2,B3GAT1,TMEM151A,PHYHIPL,GABRA2,CHL1,GAD2,GAP43,DNER,GFRA2,FREM1,PCSK1N,GPM6A,CCDC184,STMN2,GRIA2,C1QL4,GRIA4,CELF3,WIF1,NXPH2,SCRG1,HPSE2,IGFBPL1,CELF5,C2orf72,LIX1,KCNQ2,C2orf80,RSPO2,TCEAL5,NELL1,NNAT,NPY,NTRK2,OLR1,PAX6,PCDH8,PENK,GDAP1L1,HMGCLL1,PDZRN4,MAGEL2,POU3F2,NKAIN4,PRPH,PTPRN,PTPRO,RFX4,HUNK,LINC00461,TMEM200C,TMEM132D,SLIT1,CLSTN2,SST,SYT4,TAC1,TAC3,CNTN2,TF,ZIC1,CRB2,DPYSL5,STMN4,SCG2,SLC17A6" Coexpression Atlas PCBC_ECTO_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500 PCBC 9.33E-16 4.76E-12 1.45E-14 1.32E-13 153 498 "VAT1L,ASTN1,KIF1A,CA4,CAMK2A,CCK,CDH8,CDH18,LGI1,SYNPR,LHX2,IGLON5,COL9A1,GAL3ST1,TCEAL2,NRG2,IGDCC3,HAPLN1,LRRC3B,NCAN,CNTNAP2,PLCXD3,CTNND2,RIMS3,DGKG,LYPD1,SNAP91,CDON,FAM57B,EFNA2,ELAVL4,EMX2,TMEM74,ADGRV1,CLVS1,FABP7,ZIC4,SPSB4,C1orf61,ATP13A4,B3GAT1,PHYHIPL,ILDR2,SALL3,IP6K3,GLDC,AIFM3,PRUNE2,GPM6A,DIPK1C,LPAR4,GRM3,PTPN5,SOX21,GUCY1B1,TMEM179,CELF3,UBE2QL1,IGSF21,HAPLN2,IGFBPL1,CELF5,ATCAY,BTBD17,HES5,LIX1,INSM1,ZNF385B,KCNA1,OLFM3,KCNQ2,KIF5C,LRRC4B,CLEC18A,MAP6,SESN3,BCO1,SCG3,DDX25,TCEAL5,NELL2,NHLH1,NNAT,NPY,IGSF11,KCNK10,PAX6,PRTG,ENPP2,PLP1,HMGCLL1,SDK2,NECAB2,MAGEL2,POU3F2,NKAIN4,LAMA1,ELOVL2,PTPRD,STRC,TMEM255A,FEZF2,PRRT2,RFX4,RLBP1,ZFHX4,KLHDC8A,FAM182A,SLC30A10,TMEM200C,SCG5,ARX,SLC1A6,PKNOX2,SLCO1A2,DMRTC1,RIMS1,SOX1,SOX3,SOX15,LHFPL4,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SOX21-AS1,ZFR2,TAC1,UNC5D,VWA3A,PCDHA6,PCDHA3,PCDHA2,THBS4,NR2E1,RIMBP2,CA14,TTPA,CLEC2L,RBFOX3,ZIC1,KCNT2,EMX2OS,CRB2,MKRN3,DPYSL5,LAMP5,CADM2,STMN4,GAL3ST3,DOCK8,JPH3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.06E-15 5.42E-12 1.64E-14 1.50E-13 132 408 "EMILIN3,ADCY5,SORCS1,USP31,TAOK1,PCDH10,DPP10,ANK3,APAF1,APC,PHYHD1,LGR5,CASK,BCHE,NRP2,BMP7,DST,CACNA2D1,CANX,VSTM2A,RUNX1T1,INA,CDH10,CHGB,RAB3C,CNR1,FAM171B,CRMP1,ANKRD44,VCAN,HDAC9,TOX,JAKMIP2,MFAP3L,ARNT2,KBTBD11,HS3ST4,DPYSL2,DRD1,ABCC9,EDNRA,EDNRB,HIPK3,SEMA3D,EGFR,CALCRL,EPHA5,ETV1,EYA1,TMEM132C,DLC1,CAP2,FOXF2,SGIP1,CELF1,DACH2,MEGF10,CHL1,IQGAP2,GFRA1,PCDH17,GHR,PPARGC1A,GLRB,PCDH11X,FERMT2,STMN2,GRIA2,GRM3,GRM7,GUCY1A1,GUCY1B1,WIF1,KLF12,ZDHHC15,IFI16,IL6ST,KCND3,KCNMA1,KIF5C,ASPRV1,KITLG,PPM1L,MKLN1,RSPO2,NAP1L2,NDP,NEFM,NFIA,NPTX2,CLDN11,PDE3A,PDGFRA,GPR85,PIK3C2A,PCDH18,TRHDE,PRRX1,FAT3,KANSL1,PRPH,FAT4,REV3L,ZFHX4,SETD5,RTN1,RYR3,SALL1,CSRNP3,SCN3A,TNFRSF19,SLC15A2,SNAP25,SOX2,ZHX3,NPAS3,SMOC1,EPB41L3,NEK4,MTCL1,FBXW11,TBL1X,NSD1,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRIO,TRPS1,RPRM,MSRB3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.13E-15 5.78E-12 1.75E-14 1.59E-13 79 196 "SORCS1,PCDH10,FAM135A,RNF182,LDLRAD4,PTBP2,RUNX1T1,CDH2,DCLK1,SYNPR,SLC35F1,HAPLN1,ERC2,APPL1,HDAC9,TOX,CEP170,EDNRA,TENM1,EPHA5,EYA1,TMEM132C,UBE2E3,FOXF2,SGIP1,DACH2,MEGF10,GABRB1,DNER,GLRB,RAB40B,GRM3,MAP4K5,WIF1,KLF12,CELF5,IFI16,LRRTM3,KCNK2,SMAD1,MYH3,MYO5A,NAP1L2,PAK3,GPR85,NLGN3,PCDH18,HMGCLL1,TRHDE,PRRX1,ZIK1,FAT4,GAL3ST4,NUDT11,ZFHX4,ROBO1,SALL1,CSRNP3,LRRTM4,FAM19A1,NTNG1,DZIP1,ANKRD6,SLC15A2,SOX11,NPAS3,ELOVL4,KLHL7,PLCB1,ADGRL3,PCDHB3,ASXL3,ZFP91,TRPS1,SSBP2,RPRM,MKRN3,LRP8,SOCS4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.52E-15 7.77E-12 2.34E-14 2.13E-13 32 46 "VAT1L,CADPS,INA,FEZ1,SCRN1,ELAVL2,EYA1,FABP7,TUBB3,GAP43,SYT17,IGSF5,GFRA1,GNAO1,STMN2,LIX1,L1CAM,SCG3,NEFM,NELL2,MAPK10,RET,RTN1,FAM19A1,SCG5,SNAP25,SCN3B,SYT11,SYT1,CUX2,TMEFF2,STMN4" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500_K0 facebase_RNAseq_e10.5_OlfacPit_2500_K0 Gudmap RNAseq 1.79E-15 9.15E-12 2.75E-14 2.50E-13 245 926 "DPF1,TTYH1,SYN3,NCKAP5,KDM5D,FMNL2,TMCC3,GRAMD1B,KIAA1211,KLHL13,PCDH19,KIAA1324,OSBPL6,DOC2A,AMPH,ANK3,CNIH2,APBB1,APC,APLP1,DGKZ,PHYHD1,LGR5,ARHGDIG,CADM3,KIF1A,BCL7A,BLM,ZNF599,PROM1,BMP7,BMPR1B,WASF1,CACNB2,HAP1,PTBP2,BRSK2,USP2,MTMR7,CBFA2T2,CDH2,CBARP,CHGB,CHN2,SLIT2,KIAA1549L,NRXN1,MYL6B,TMEM59L,CNTFR,AKAP7,IQCK,LETMD1,SLC4A7,SLC4A8,BAG4,MYRIP,NECTIN3,ZNF385A,CRMP1,GDA,LRIG1,IPCEF1,FAM169A,UBXN2A,KATNAL2,KIAA0586,TMEM170A,SNAP91,USP3,SLC29A4,CDON,DTNA,DUSP9,E2F5,SEZ6L2,FSD1L,EFNA2,EFNA3,EGFR,ELAVL2,EPB41,EPHB1,KCNMB2,ANKRD13B,SLC43A2,ETV1,CEND1,EXTL2,EYA1,REEP2,TUBB4A,ATP8A1,CEP78,FDFT1,MED12L,OLFM1,SPSB4,FGF12,AMOTL2,IQCG,NOP56,SYT3,DPYSL4,SMC2,HVCN1,TPK1,KHDRBS3,PHYHIPL,GATM,GCNT2,PCDH17,GGT7,RUNDC3A,DBF4,GLI2,GLRB,TOX3,KCNMB4,GNAO1,GNG3,GPD2,GPM6A,GPM6B,B4GALNT4,CECR2,STMN2,RNF165,MFSD2A,PSIP1,FAM107A,FAM222A,FRMD5,HSF2,HSP90AA1,SHISAL1,TUBB2B,KIF5C,KIT,MAOB,MAP2,AQP11,MEIS1,KCTD6,MSI1,TAGLN3,MXI1,MYBPC1,MYCN,NASP,RCOR2,NEFM,NOVA2,ODF2,PAK3,PBX1,PDE1B,SNX10,RETREG1,SLC25A23,POLR2F,FSD1,PPP1R1A,NKAIN4,RASGEF1B,MAPK4,GDPD1,SLC22A23,ELOVL2,SPDL1,ZIK1,EML5,NKAIN1,CEP97,CCDC40,ROGDI,RBBP8,FIGN,NUDT11,KLHDC8A,RAVER2,RPL15,RIMKLA,LGR4,RTN1,CCDC112,SALL1,MAPK12,LRRTM4,HES6,ZFP2,TRIM46,HSPA4L,SCG5,KIF21A,ST6GAL1,CCDC92,CLSTN1,CXXC4,RIMS1,SCN3B,KIF21B,SOX11,SP4,CLSTN2,SST,KANK1,SYT11,FGD4,SYP,SYT5,MTCL1,MCF2L,WSCD1,CUX2,ITGB3BP,AKTIP,HEY1,TNNT1,RGMB,PRMT8,TRPS1,HSPBP1,TST,CADM1,AMOT,SLAIN1,FAM181B,USP1,MEAF6,ZFP41,NDRG4,SLC26A10,ZNF184,SMARCAD1,MEIS3,SHD,SLC38A1,TUBA1A,ADAMTS9,NAV2,WNK2,AMN1,FZD3,PHTF2" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.94E-15 9.88E-12 2.96E-14 2.70E-13 111 323 "RNF157,PNMA8B,TAOK1,ARHGAP20,PKP4,DOCK11,BACH1,SGCE,RUNX1T1,CDH2,ZNF445,SRSF11,CHM,SLIT2,PLAA,NMT2,FAM171B,RBM39,TENM4,FGFR1OP2,GAPVD1,TCAF1,KIAA0586,AIF1L,ZEB2,CEP170,ZC3H11A,EDNRA,EIF4G1,CALCRL,EPB41L2,SRRM1,ANKFY1,SMC2,APOPT1,ILDR2,WASF3,TUBGCP4,SRCAP,BRD8,PCDH11X,LPAR4,CACFD1,CIT,MIER3,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,MSI1,MYBPC1,HNRNPM,NAP1L3,NASP,CNOT4,PCDH9,PDPK1,OLA1,PRRX1,KANSL1,MAPK8,PTN,CEP97,TMEM255A,C1orf54,MSANTD2,RFX3,PBRM1,TMLHE,PCMTD2,MEG3,NCBP3,SATB1,FNIP1,TRA2B,ITSN1,CHD9,PREX2,SLC12A2,NAPB,SCMH1,TET1,SNCA,UNC5B,ZC3H13,KIF1B,TROVE2,CLSTN2,PRRC2C,SYNE2,AHCYL2,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,FLRT2,NSD2,PCDH20,ZFP37,ZNF711,TRIM9,ADAMTS9,SNX27,KCNAB1,FIP1L1,FZD3,JMJD1C,GAN,SENP7" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.05E-15 1.05E-11 3.12E-14 2.85E-13 236 884 "TTYH1,ABAT,KDM5D,TMCC3,PNMA8B,GRAMD1B,ADORA1,MTA3,HECW2,NR0B1,BCAR3,KCNT1,AMH,SEMA7A,USP28,PPFIA1,GAS7,DGKD,USP37,SHTN1,LGR5,CDC14B,KIAA1614,PPP4R4,TMEFF1,ARHGDIG,CADPS,MARK4,DDX3Y,ATP1A1,ATP1A2,ATP2A2,ATP2B3,ALDH7A1,N4BP2L1,DPY19L3,BCHE,RGS11,DST,ST3GAL5,SYNJ2,MAP7,PRC1,RGN,SLC16A4,SCARB1,CDH2,CDO1,CACNA2D2,ADGRG1,JAM2,CLU,CLTB,FADS2,PICK1,SUMF2,COL9A2,COL9A3,AKAP5,MAGED1,NCOR2,MICAL2,VCAN,CST3,PLXNA4,PPP1R16B,GPRASP1,TOX,DAPK1,SCRN1,DBI,DBT,DCT,JAKMIP2,ELMO1,PLPPR4,SRGAP3,KIF19,CD99L2,RCAN1,GNE,DTNA,DTNB,MAMLD1,TSPAN5,SIDT2,MRO,PLXNC1,SORBS3,CERCAM,MTSS1L,EPS8,ERBB2,ERBB4,ETV1,RASL12,CEND1,EYA1,F3,REEP2,FAM198B,FABP7,PTK2B,TUBB3,ATP8A1,FGF13,SEMA6C,FOXO3,AFF2,CAMKK2,CSPG5,FYN,GAA,GAB1,BRPF3,IQGAP2,ERAP1,SEPT9,GATM,PPARGC1A,OS9,LOXL3,PSRC1,ADGRA3,GPM6B,GPR37,RAPGEF4,PADI2,HSD17B1,SHISA6,DOCK7,TUBB2B,LRRTM3,ITPKB,KCNH1,KLHL23,KCNK2,TTYH2,SYTL4,HECTD2,NCOA7,MAN2A2,MATN2,MEF2C,KITLG,AFF1,MOV10,MSI1,NRBP2,CTNNA3,MTR,MYO7A,FXYD6,NELL1,NFIA,CLDN11,PAK3,ETFRF1,PDE2A,PGAM2,SERPINE2,SERPINI1,PLCB2,MTRF1L,PSAT1,SCHIP1,PPP3CC,RASGEF1B,PRKCB,MAPK3,MAPK4,EPDR1,MASP1,PTCH1,PTPN13,PTPRD,PTPRE,SH3TC2,DUSP15,ROBO1,TMEM206,PCMTD2,TMEM100,GLDN,RPS6KA2,MEG3,SOX8,SOX6,GALNT10,MRAS,KIF21A,SH3GL2,FRMPD1,DOCK10,ST6GAL1,ST8SIA1,SLC6A8,EFHD1,TNIK,SOX5,SOX10,UHRF1BP1L,SPP1,TSPYL2,SMOC1,ST5,ADHFE1,FGD4,SYNE2,TACC1,MTCL1,SEMA4A,MLST8,SIN3B,SZT2,OBSL1,ZFPM2,THRA,TIAM1,BEX4,TPD52,WBP2,TRPC3,FNDC5,TST,SGK3,LMF1,INTS3,SLC38A1,ADAMTS9,NAV2,WNK3,FZD3,NHSL1,NETO2,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hGaba_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.65E-15 1.35E-11 4.02E-14 3.67E-13 28 37 "KIDINS220,ANK3,CDK5R1,RUNX1T1,INA,NRXN1,KIAA0408,NTM,ELAVL4,NSG2,GAP43,DNER,PCDH17,PCLO,STMN2,GRIA2,KIF3A,NCAM1,NNAT,REV3L,RTN1,SCN2A,SCN3A,SCN3B,MYT1L,SYT1,CELF4,REEP1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2c_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.07E-15 1.56E-11 4.63E-14 4.22E-13 41 71 "TTYH1,NDRG2,SPARCL1,ATP1A2,ADGRB1,ADGRG1,NCAN,CST3,SDC3,RASSF2,DBI,LYPD1,NTM,OLIG1,EDNRB,OLIG2,ETV1,FABP7,C1orf61,DNER,PCDH17,LUZP2,GPM6B,SCRG1,HES5,FGFBP3,MT3,SCG3,NFIA,NTRK2,SERPINE2,PMP2,SCHIP1,PTN,PTPRZ1,RIT2,S100B,BCAN,SLC1A2,SLC1A3,ZEB1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_500 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_500 FaceBase_ST1 3.07E-15 1.56E-11 4.63E-14 4.22E-13 119 358 "DPF1,TTYH1,ACADM,ERMN,PCDH19,TAOK1,ABCD2,APBA2,UPRT,ASCL1,CCDC181,RNF182,TTC9B,RAB29,ISPD,PRC1,CLDN10,INA,ADGRG1,JAM2,LHX2,RAB33A,CLCN3,QKI,FEZ1,CNTNAP2,TOX,SCRN1,JAKMIP2,GSDME,SRGAP3,DLX1,ATL1,ELAVL3,FABP7,FOXG1,EFCAB2,CSPG5,PHYHIPL,GAD2,KIAA1841,IGSF5,GLDC,GNAO1,GPM6A,GPM6B,GPR19,LPAR4,RNF165,SOX21,UBE2QL1,IGFBPL1,USP51,TCEAL6,HES5,LIX1,INSM1,TUBB2B,LRRTM1,LMO1,LSAMP,MDM4,MEIS2,MT3,SCG3,LYRM9,MYO9A,NEFM,NELL2,NFIA,NOVA1,PAK3,PAX6,SLC10A4,GDAP1L1,C11orf49,STRN3,SCHIP1,MINDY2,NKAIN4,PKIA,GDPD1,PTPRZ1,PTX3,TUG1,FEZF2,TSPY26P,PBRM1,LINC00461,HSPA4L,SCG5,KIF21A,SH3GL3,SLC4A3,TET1,SOX2,NPAS3,TROVE2,ELOVL4,ACSBG1,SYT11,ADAMTS17,SLC35G2,CCDC173,C18orf54,HEY1,NR2E1,C9orf85,TRPS1,FAM181B,WNT7A,XRCC4,ATP6V0E2,PMEPA1,STMN4,STOX2,PARP11,AMN1,NETO2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Top 200 Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Top 200 LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.16E-15 1.61E-11 4.76E-14 4.34E-13 264 1022 "DPF1,SDE2,ACTN1,NDRG2,AXIN2,PTCHD1,AGT,CC2D2A,C1QTNF1,SPARCL1,SRPX,LTBP4,FAM135A,OGT,APAF1,GAS7,PHYHD1,USP37,TMEM263,CASK,ARHGAP5,RGS20,NCOA1,ATP1A2,ALDH7A1,MPDZ,NRP2,FUBP1,MTMR3,MTMR2,SGCE,CACNA1D,CACNA2D1,CACNB2,PTBP2,RUNX1T1,CBR1,ENTPD2,CD81,CDO1,CFL2,CHN1,CHRM4,B4GALT6,SLIT2,CNN3,MAGED1,CNRIP1,CP,RBM39,AKAP12,SNCAIP,VCAN,NCAN,GREB1,GPSM1,BOC,DOCK4,HDAC9,MYADM,DAPK1,BRINP1,ZEB2,BLOC1S6,CCDC3,DMD,SHANK1,DPYSL2,RCAN1,DTNA,ECM2,ABCC5,GOLT1B,EDNRA,EDNRB,TMTC1,CERCAM,MRNIP,PCOLCE2,BSCL2,EML1,PAN3,EPB41L2,LRRC17,EPHA5,NCALD,ETV1,RASL12,TMEM132C,DLC1,FECH,FGF13,FGFR1,FGFR3,FHL1,UBE2E3,FOXF2,NOP56,JKAMP,CINP,ERGIC3,PNMA2,ZMAT1,STAG2,DKK3,DENND2A,ZMYND11,CPLX2,AHDC1,GFRA2,FREM1,CSDC2,SPIN1,HTATSF1,FERMT2,GPM6B,GPER1,RAPGEF4,GRB10,DIDO1,NR3C1,ATE1,GSN,GUCY1A1,GUCY1B1,GYG1,WIF1,GPR45,HNF4G,IGF1,IL11RA,ITGAM,KCNA2,KCNK3,TTYH2,LAMA2,MAN2A2,MAPT,CHIC1,LDLRAD3,MEST,MN1,CCDC80,PTOV1,MYO9A,NAP1L1,FXYD6,NCAM1,NDP,SFR1,NFIA,NFIX,NNAT,NPR2,NRCAM,DDR2,NUCB1,ZNF827,PAX6,PBX1,PCDHGC3,PCSK5,PDGFRA,ENPP2,PENK,SERPINE2,PIK3R1,PKD1,ZFYVE21,FTO,SMOX,FXYD1,ANKRD16,PMP22,EXOSC10,SCHIP1,SEPT4,POU3F2,NKAIN4,PRKACB,MAPK7,BCAS3,CNTLN,PTCH1,PTH1R,OCIAD1,PID1,CEP97,ACSS3,ZCWPW1,ZYG11B,REV3L,SEC61A2,ZFHX4,ROBO1,ROBO2,LGR4,ZNF354C,S100B,SCN7A,TNFRSF19,SFPQ,SEC31A,DZIP1,ABLIM3,SLC1A3,PREX2,SMTN,SMARCE1,LIMCH1,LMBRD1,PALLD,PDZRN3,TRERF1,SOX5,ZCCHC24,CAND2,MYCBP2,RBM26,C11orf87,CLASP2,SAMSN1,KANK1,GANAB,SYT11,FGD4,ADAMTS17,TACC1,TAF6,PDLIM2,TCEA1,TCF7L2,TCF12,USP22,AP4E1,TGFBR3,HHIP,THRA,NACC2,CBX5,DAAM2,TRPS1,FNDC5,SSBP2,RFTN2,TTC3,EIF4ENIF1,UBE2H,PLEKHH2,VIPR2,VLDLR,ZIC1,ZNF32,ZSCAN26,SPIRE1,PMEPA1,TUBA1A,ADAMTS9,ST7,CAMK1G,RNF170,ADAMTS10,ST8SIA2,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 3.75E-15 1.91E-11 5.63E-14 5.13E-13 202 728 "TTYH1,ADD3,AK2,SPARCL1,ALCAM,CCDC146,PPFIA1,NT5C3B,LRRC4C,ARHGAP5,CADPS,ASCL1,CCDC181,BARD1,MPDZ,SEC11C,BMP7,ARHGEF7,FUBP1,THSD7A,VXN,SPAG9,PRC1,SEPT7,CDH2,LGI1,CDO1,SOCS6,CHN2,JAM2,RAB33A,NRXN1,CLU,MYL6B,IGDCC3,NECTIN3,HINFP,TENM4,NCAN,CTNND2,TOX,DCC,ZEB2,MAGI2,LYPD1,SGSM2,CHRDL1,RCAN1,DTNA,EDNRB,EEF1D,EFNB3,FAM13A,PHF20L1,AASS,COPS4,EN2,EFS,ADGRV1,FAM198B,FABP7,FDFT1,FGFR3,BAIAP2,CAMSAP1,C1orf61,CAP2,SMC2,SPECC1,PDLIM5,MEGF10,ILDR2,NKX6-2,SALL3,FREM1,BRD8,RND1,DBF4,CBX1,GPM6B,NUDT21,STMN2,GRM3,TOX2,ELOVL5,HMGB1,SCRG1,HMGCR,CFAP126,BTBD17,HES5,ITGA7,KIF5C,STMN1,FGFBP3,LSAMP,MAP6,MEST,KITLG,MN1,CCDC80,MSI1,MTTP,MXI1,BEX5,NASP,NELL2,NKX2-2,NNAT,NPTX2,NRCAM,NRDC,NTRK2,CNTN3,PCDH8,PDE3A,ENPP2,PDPK1,ANLN,PKM,GPSM2,PLCL1,PLP1,PLTP,FAT3,NXPH1,POU3F2,IRX1,LRRN3,PPP2R5E,VSTM2L,MAPK4,HYDIN,SLC22A23,LAMA1,PTCH1,SPDL1,PTPRO,C1orf109,PTPRZ1,PTX3,RALGDS,ARID4A,VEPH1,ZMAT4,RFX2,RFX3,RFX4,NUDT11,NEK11,RPS20,RMI1,SALL1,SCN7A,HES6,SFPQ,PUF60,PPP1R9A,ANKRD6,SEPHS1,TET1,EPC1,SMARCE1,LIMCH1,MYO16,SOX1,SOX2,SOX3,SP2,NMNAT2,SPP1,PEG10,SPART,LMO3,POGZ,ITPRID2,SULF2,SYNE2,SYT4,WWC1,ZEB1,TCF12,PSD3,NSD1,CRTC1,CCDC173,DNAH7,TMPO,SEZ6L,TRPS1,PPIL6,FLRT2,USP1,NSD2,WNT7A,TRIM9,LAMP5,PMEPA1,RGMA,LMAN2L,FZD3,IFT88" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 5.03E-15 2.57E-11 7.52E-14 6.86E-13 57 122 "TTYH1,SHTN1,PTCH2,ATP2B2,DIRAS1,HAP1,DNAJB5,MAP4K4,NCAN,SLITRK5,DTNA,ELAVL3,OLIG2,PLEKHO1,EPHB1,APC2,ADGRV1,REEP2,TUBB3,FOXM1,NSG2,DLL3,SRRM4,STMN2,GRIK2,RNF165,CELF3,TOX2,FRMD5,IGFBPL1,HES5,MAP2,CPNE9,ADAM22,NRCAM,POU3F4,GAL3ST4,CCDC112,HSPA4L,SCG5,SOX5,SP2,SEPT3,SYT11,FGD4,TCF4,TUB,MGAT5B,ZIC3,ZNF24,EML6,DPYSL5,SHD,STOX2,FZD3,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K4 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 5.61E-15 2.86E-11 8.37E-14 7.63E-13 59 129 "PTCHD1,GPRASP2,SEMA4G,MADD,RGS20,CACNA1A,CACNB2,HAP1,CDC25B,NRXN2,CNTFR,CSF2RA,ATRNL1,ST18,DNAL1,SV2A,SRGAP3,ARNT2,APC2,FOXG1,SRRM4,FAXC,LOXL3,PCLO,GRIK2,FRMD5,CELF5,ATCAY,IGSF1,LRRTM1,KCNH2,L1CAM,LSAMP,MAP2,MXI1,NUCB2,PAK3,PAX6,GDAP1L1,ZFYVE21,GAL3ST4,PRRT2,SCG5,SLC1A3,SORCS3,SNAP25,DOP1A,SOX2,SEPT3,ANKRD12,NACC2,NR2E1,PRMT8,MGAT5B,PLPPR2,CCDC136,NPDC1,ZNF23,SENP7" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.78E-15 2.95E-11 8.59E-14 7.83E-13 211 773 "NCKAP5,KDM5D,NDRG2,ADCY2,ADCYAP1R1,PNMA8B,GRAMD1B,SORCS2,SEMA6A,ALCAM,ARHGAP20,LTBP4,AMH,SEMA7A,APAF1,GPAM,APOC1,CDC14B,TMEM263,DDX3Y,ATP1A3,ADAM23,CACNA1G,CACNA2D1,CACNB2,ISPD,RUNX1T1,PRC1,ARHGEF25,CBLN1,LDB2,SCARB1,AP4M1,REPS2,JAM2,SLIT2,NRXN3,CLU,FADS2,CNTFR,MAGED1,SNCAIP,TENM4,MICAL2,ATRNL1,VCAN,BOC,MYADM,RIPOR2,ARHGAP24,ARMCX2,ZEB2,HEPH,SRGAP3,DNM1,CD99L2,CDON,ABCC9,TSPAN5,EDNRA,HEYL,CACNG7,EGFR,MRO,PLXNC1,EPB41L2,LRRC17,RASGRP2,EPS8,ERBB4,NRN1,FAM198B,FABP7,PTK2B,TUBB3,DLC1,FDFT1,KIAA1109,FGF13,TMEM164,FLNC,AFF2,GABRA4,TRAF3IP2,IQGAP2,SEPT9,GATM,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,RAB30,PCDH11X,ADGRA3,GPM6B,FUT10,STON1,LPAR4,GRIA4,PRDM5,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,ELOVL5,HPSE2,HMGCR,ZDHHC15,LRRTM3,KCND3,KCNJ3,KLHL23,KIT,LAMA2,LSS,MATN2,CHIC1,MEF2C,MEIS1,MMP16,CCDC80,LAYN,MYO9A,NEXMIF,NCAM1,ZC3H12B,NFIA,NFIX,NNAT,NPY,PAK3,PCDH9,PDE1A,PDE3A,PDGFRA,PENK,SERPINE2,ANLN,FXYD1,PCDH18,PLTP,FAT3,SH3KBP1,LRRN3,RASGEF1B,MAPK9,MASP1,SYTL2,LAMA1,PTCH1,PTN,TUG1,TMEM255A,ZCWPW1,SLC6A15,REV3L,RNASEL,ROBO2,ARMH4,ACER3,LGR4,MEG3,ZNF354C,SATB1,LRFN5,SCN2A,SCN7A,NTNG1,PKNOX2,SLC8A1,ARFGAP1,SORCS3,PALLD,ZCCHC24,CAND2,PEG10,ZNF423,TSPYL2,SMOC1,ST5,SULF2,ACSBG1,SYNE2,ARHGEF9,ADAMTS17,PJA1,ADGRL3,PCDHB10,PSD3,OBSL1,ZFPM2,TGFBR3,HHIP,THRA,TPM1,TRPS1,SSBP2,RFTN2,TMEFF2,PLEKHH2,VSNL1,CLDND1,PMEPA1,STOX2,ADAMTS9,WNK3,NETO2,DPF3,ST8SIA2" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.42E-15 3.27E-11 9.51E-14 8.67E-13 217 802 "EMILIN3,KDM5D,ADD1,ADD3,PNMA8B,PCDH19,WDR35,TAOK1,ARHGAP20,LTBP4,LCORL,PKP4,CASK,ASPH,PTCH2,DDX3Y,ATP2B1,RNF182,DOCK11,BACH1,ADGRB3,C1QC,SGCE,IL33,BTRC,VSTM2A,RUNX1T1,LDB2,CDH2,ZNF445,SRSF11,CHM,SLIT2,KMT2C,PLAA,NMT2,COL4A5,RBM39,CLIP3,TENM4,CSF1R,DZIP3,PUM1,CX3CR1,FGFR1OP2,GAPVD1,TCAF1,MATR3,AIF1L,ZEB2,ZC3H11A,GSDME,ALKBH8,G3BP2,CDON,EDNRA,EDNRB,SEMA3D,APH1A,EIF4G1,EMX2,EPB41L2,LRRC17,SRRM1,ETV1,TMEM132C,SCML2,FCGRT,PRMT5,KIAA1109,MEX3B,SEMA6C,ANKFY1,NBEA,SMC2,APOPT1,ILDR2,GATM,SRCAP,CSDC2,TNRC6A,PCDH11X,LPAR4,STMN2,DIDO1,PARD3B,GRIK1,NR3C1,PRDM5,GRM7,KIF3A,KAT7,GUCY1A1,WIF1,MAEL,RASSF8,HAS2,KLF12,MIER3,NKD1,KCND3,LIFR,MAP4,MATN2,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,MYBPC1,NASP,NCAM1,NFIA,NFIX,CNOT4,OCRL,PCDH9,PCSK5,PDPK1,NALCN,PIK3R1,PLCL1,PLEC,PLTP,RC3H2,PMS2,PRRX1,FAT3,SH3KBP1,LRRN3,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,SUSD4,MSANTD2,RNASEL,TMLHE,ROBO2,PCMTD2,MEG3,NCBP3,SATB1,CSRNP3,ATXN2,FNIP1,SFPQ,TRA2B,ARX,CHD9,FNDC3A,WDR37,SLC12A2,SCMH1,TET1,CPEB4,ARFGAP1,ZKSCAN3,SMARCA4,ZCCHC24,SP4,SPP1,UNC5B,ZC3H13,KIF1B,RBM26,TROVE2,CLSTN2,RGL1,SULF2,PRRC2C,SYNE2,ANKRD12,KLHL4,CUX2,TCF7L2,WASHC4,CLASP1,PCDHB9,OBSL1,AHCYL2,HIF3A,CBX5,ASXL3,R3HDM1,TNS1,RBFOX2,TPM1,NR2C2,TRIO,TRPS1,TSC1,SSBP2,UBE3A,UBTF,FLRT2,FLRT1,VLDLR,TBC1D15,WNT7A,ZFP37,ZNF711,TRIM9,ZNF142,PMEPA1,ADAMTS9,NAV2,SNX27,FIP1L1,JMJD1C,RNF170,ST8SIA2,GAN,SENP7" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000 DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.06E-15 4.11E-11 1.19E-13 1.09E-12 212 780 "TKTL1,TMCC3,ADD1,ADD3,PNMA8B,ADORA1,PWWP2A,INTS2,NME5,NR0B1,TAOK1,LTBP4,LCORL,PKP4,DGKD,LGR5,ARHGAP5,PDE8B,ASPA,CAPRIN2,DDX3Y,INSYN2B,BACH1,RGS11,SYNJ1,ARHGEF7,SCAPER,JAZF1,SGCE,BTRC,CACNB2,CALB1,RUNX1T1,LONRF2,ZNF445,CRLF1,SRSF11,CHM,SLIT2,KMT2C,CLU,NMT2,CNR1,COL4A5,ABI3BP,RBM39,TENM4,DZIP3,GREB1,PUM1,DOCK4,HDAC9,FGFR1OP2,TCAF1,AIF1L,MAGI2,TMEM130,ZC3H11A,GSDME,SACS,G3BP2,DYNC1I1,CDON,SLC12A6,DRP2,DNAJB6,EDNRA,RASGRP1,PLXNC1,EIF4G1,ELAVL2,CALCRL,EMX2,EPB41L2,LRRC17,SRRM1,EZH1,NRN1,SCML2,KIAA1109,MEX3B,FOXO3,SMC2,APOPT1,ATP6V1H,B3GAT1,ZMAT1,GABRA4,GABRB1,ILDR2,GATM,TUBGCP4,SRCAP,GGT5,TNRC6A,AIFM3,MAP7D2,TDRKH,LPAR4,GRK4,NR3C1,KIF3A,GUCY1A1,MAEL,MIER3,SHISA6,ZNF385B,KCND2,KIT,SYTL4,MAP4,CHIC1,KITLG,MMP16,SAMD5,DDX25,RSPO2,MYO5A,NEXMIF,NASP,NELL1,NOS1,CNOT4,GLIPR1L2,PCDH9,PDPK1,OLA1,ABCB1,SERPINI1,SEMA5B,PIK3R1,PLEC,PLP1,RC3H2,PPP2R5E,KANSL1,MAPK8,MAPK10,GDPD1,FAM120C,TMEM255A,C1orf54,RNASEL,TMLHE,PCMTD2,MEG3,SATB1,LRRTM4,PRCD,FNIP1,TNFRSF19,SFPQ,TRA2B,HSPA4L,ARX,KIF16B,CPEB3,SYBU,WDR37,SLC12A2,SLC14A1,SCMH1,CPEB4,ZKSCAN3,SNCA,MYT1L,SOX5,ZCCHC24,ZC3H13,KIF1B,RBM26,TROVE2,CLSTN2,LARP4,PRRC2C,SYNE2,SLC37A2,ANKRD12,CAMTA1,DMXL2,WASHC4,CLASP1,DOCK9,PCDHB9,OBSL1,AHCYL2,CCDC173,TEX15,DNAH7,CBX5,ACTR6,R3HDM1,RASD2,NR2C2,FNDC5,TSC1,SSBP2,UBE3A,UCHL1,UGT8,TBC1D15,ZNF711,ZNF23,NDRG4,REEP1,WNK1,ADAMTS9,NAV2,SNX27,PHTF2,RSPRY1,GAN" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.08E-15 4.63E-11 1.34E-13 1.22E-12 61 137 "PCDH10,DPP10,TNRC6C,ASTN1,ADAM23,CACNA1B,RUNX1T1,CDH10,FAM171B,ANKRD44,SNCAIP,SIPA1L1,PYGO1,TOX,JAKMIP2,GRIN3A,HS3ST4,CALN1,CACNG7,EGFR,ETV1,EYA1,TMEM132C,FOXF2,SGIP1,DPYSL4,DACH2,GFRA2,B4GALNT4,GRIA2,GRM3,IFI16,JAKMIP3,RSPO2,NDP,NEFM,CLDN11,GPR85,SSH1,TRHDE,PRRX1,FAT4,ZFHX4,ARMH4,SALL1,SCN3A,TNFRSF19,NTNG1,NPAS3,EPB41L3,ARHGEF9,MTCL1,ADGRL3,CUX2,FAM189A1,PCDHB7,TIAM1,TRPS1,RPRM,FMN2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA2_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.00E-14 5.12E-11 1.47E-13 1.34E-12 39 67 "TMCC3,KLHL13,PCDH10,ANK3,INA,KIAA0408,DCC,NTM,ELAVL2,ELAVL4,EN2,RCAN2,FABP7,NSG2,NSG1,FUT9,DKK3,GAP43,GPM6A,STMN2,GRM5,SHISAL1,LSAMP,NCAM1,PBX1,PDZRN4,POU6F1,RTN1,SCN3A,SNCA,MYT1L,PEG10,BEX1,LMO3,DOK6,TUB,UCHL1,CELF4,REEP1" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500_k2 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.01E-14 5.13E-11 1.47E-13 1.34E-12 68 162 "PNMA8B,PKP4,DOCK11,BACH1,SGCE,RUNX1T1,LDB2,ZNF445,SRSF11,SLIT2,PLAA,FGFR1OP2,TCAF1,AIF1L,ZEB2,ZC3H11A,CDON,EIF4G1,EPB41L2,SRRM1,ANKFY1,SMC2,APOPT1,SRCAP,PCDH11X,LPAR4,GRIK1,HAS2,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,NASP,PCDH9,PIK3R1,PRRX1,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,TMLHE,MEG3,NCBP3,ATXN2,TRA2B,CHD9,SCMH1,TET1,SNCA,ZC3H13,TROVE2,PRRC2C,AHCYL2,CBX5,R3HDM1,TRPS1,SSBP2,UBE3A,FLRT2,NAV2,SNX27,FIP1L1,GAN" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k3_1000 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.07E-14 5.45E-11 1.56E-13 1.42E-12 98 277 "RNF157,PNMA8B,ARHGAP20,PKP4,ASPH,ATP2B1,DOCK11,BACH1,SGCE,RUNX1T1,CDH2,ZNF445,SRSF11,SLIT2,PLAA,COL4A5,TENM4,FGFR1OP2,GAPVD1,TCAF1,KIAA0586,AIF1L,ZEB2,ZC3H11A,CDON,EDNRA,EIF4G1,EPB41L2,SRRM1,ANKFY1,SMC2,APOPT1,GABRB1,SRCAP,BRD8,PCDH11X,LPAR4,DIDO1,GRIK1,CIT,MIER3,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,MYBPC1,NASP,PCDH9,GPR85,OLA1,PIK3R1,PRRX1,KANSL1,MAPK8,PTN,PTPRG,TMEM255A,C1orf54,MSANTD2,RFX3,PBRM1,RNASEL,TMLHE,MEG3,NCBP3,ATXN2,TRA2B,CHD9,FNDC3A,SCMH1,TET1,SNCA,ZC3H13,KIF1B,TROVE2,PRRC2C,SYNE2,AHCYL2,CBX5,R3HDM1,TRPS1,SSBP2,UBE3A,FLRT2,NSD2,PCDH20,ZFP37,NAV2,SNX27,KCNAB1,FIP1L1,JMJD1C,GAN,SENP7" Coexpression Atlas Arv_SC-HD_2500_K2 AravindRamakr_StemCell-HD_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.07E-14 5.45E-11 1.56E-13 1.42E-12 283 1125 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY8,GALNT13,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,TMEM108,KIF1A,CARMIL3,ADGRB1,CACNA1G,HAP1,SYT6,BRSK2,MAP7,CLDN10,MTMR7,SYNGR3,CDH8,DLGAP1,CACNA2D2,CHGA,RAB3C,DLGAP3,NRXN1,SLC24A2,FAM189A2,FAM19A5,SULT4A1,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,NOS1AP,KATNAL2,KIF26A,RIMS3,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,PARD6A,CHRDL1,HS3ST4,CALN1,FAM57B,DPP6,USH1C,SEZ6L2,EFNA2,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,ZNF589,OLFM1,FGFR1,HPCAL4,C1orf61,FLT1,SYT3,CSPG5,B3GAT1,TVP23A,MEGF11,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,SRRM4,IGSF5,GCK,GDF1,TTBK1,GLDC,PCDH11X,KDM2B,GNAL,GNG3,GNG4,GPM6B,GPR19,LPAR4,CECR2,GRIA4,GRIK5,GRIN1,ADAMTS8,GRIN2D,GRM3,PTPN5,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,PADI2,C1orf94,NXPH2,HRH3,ARHGAP36,HNF4G,IGFBPL1,HPCA,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,RIPPLY2,TUBB2B,KCNA6,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,FGFBP3,CHST6,MMP17,MPP2,CPNE9,JAKMIP3,ADAM22,BCO1,SCG3,DDX25,MYCN,TCEAL5,FXYD7,NAP1L2,FXYD6,NAP1L3,NEFM,NELL2,NNAT,NOS1,PCBP3,ZDHHC22,PAH,KCNK10,NLGN3,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,PLP1,PURG,PSAT1,NECAB2,MAGEL2,PACSIN1,POU3F4,PPP2R2B,PPP2R2C,NKAIN4,RAB39A,PRKCG,LAMA1,GDPD2,PTPRD,PTPRN,PTPRZ1,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,PTGR2,HUNK,RYR1,SALL1,TMEM200C,SH3GL2,PPM1E,SLITRK3,CNKSR2,SLC1A6,PREX2,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,TET1,MAST1,IGSF9B,SNCB,SOX3,KIF21B,NMNAT2,LHFPL4,HECW1,SOX21-AS1,SEPT3,ZFR2,RHBDL3,NUDT10,ARC,SYP,SYT1,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,PCDHA3,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,KCNE5,CA14,TTPA,CLEC2L,UGT8,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,DPYSL5,PLPPR5,CADM2,GAL3ST3,RGS7BP,TMEM63C,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500 FaceBase_RNAseq 1.10E-14 5.62E-11 1.60E-13 1.46E-12 148 489 "EMILIN3,ACTN2,NDRG2,ADCY2,SRPX,ARHGAP20,LTBP4,GPRASP2,PPFIA2,CDK10,ASTN1,ADGRB2,C1QC,CACNA1G,LDLRAD4,CA4,CACNA2D1,VSTM2A,REPS2,LONRF2,KCNAB3,CDH8,CDO1,CRLF1,LHX2,KIAA1549L,NRXN1,ABI3BP,IGDCC3,CREB5,HAPLN1,ANKRD44,CSF1R,FEZ1,TOX,SPOCK2,RUSC2,CCDC3,DLG2,DMD,SHANK1,DTNA,MAMLD1,SEMA3D,EGFR,RASA4,ELN,TMEM35A,EPB41L1,LRRC17,EPHA5,APC2,CHST15,FCGRT,FGF11,DPYSL4,TRIM16,TPPP3,NRG3,FYB1,JPH4,ARPP21,TMEM8B,PCDH17,PPARGC1A,ZNF276,GLRB,PCDH11X,CECR2,NR3C1,GSN,MFSD2A,WIF1,SYNPO,NEGR1,ZIC5,IL11RA,BRINP3,VWA5A,MEIS2,SRSF12,CD200,CCDC80,NEXMIF,TCEAL5,NCAM2,NELL2,NFIA,NFIX,NNAT,CNTN3,PCDH9,PRTG,PDE1A,SEMA5B,TMEM38A,PLCL1,FXYD1,NXPH1,POU6F1,IRX1,PRKAR1B,PRODH,MDGA2,ACSS3,ZMAT4,ZFHX4,MYH14,EMID1,STX1B,DGLUCY,SALL1,ATXN1,LRRTM4,SH3GL3,FERMT1,DOCK10,NTNG1,NLGN1,SLC1A2,SLC6A9,SOX10,NPAS3,CLSTN2,ZFR2,RHBDL3,ADAMTS17,PLCB1,SEMA4A,UNC5D,ADGRL3,CUX2,PHF24,FAM189A1,PSD3,KCNE5,FLRT1,TSPAN11,ZIC1,ZIC2,FMN2,PMEPA1,CADM2,LRP8,PCDH15,NAV3,TMEM163,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb2_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.15E-14 5.87E-11 1.67E-13 1.52E-12 41 73 "NDRG3,SYT13,ANK2,ANK3,ZSCAN18,INA,CHGB,NRXN1,EDIL3,ELAVL3,ELAVL4,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,PNMA2,GAP43,GNG4,STMN2,CELF5,MARK1,BEX5,NAP1L3,PCSK1,PPP2R2B,VSTM2L,PTPRN,RTN1,SCN2A,PPP1R9A,SNAP25,SCN3B,PLCB1,SYT4,DNAJC12,VGF,CELF4,REEP1,SCG2,PIANP" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 40 GSE76381_iPSMoleculeCountsPMLog2 1.17E-14 5.98E-11 1.69E-13 1.54E-12 51 104 "NDRG3,SYT13,ANK2,ANK3,ZSCAN18,CACNA1B,INA,DLGAP2,CHGB,NRXN1,TMEM130,EDIL3,SEZ6L2,ELAVL3,ELAVL4,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,PNMA2,GAP43,GNG4,STMN2,CELF5,MARK1,MGAT3,SAMD14,BEX5,NAP1L3,PCSK1,PPP2R2B,VSTM2L,PTPRN,RTN1,SCN2A,PPP1R9A,SNAP25,SCN3B,LMO3,PLCB1,SYT4,TAC1,DNAJC12,VGF,CELF4,REEP1,SCG2,SLC17A6,PIANP,NETO1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_250 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_250 FaceBase_ST1 1.29E-14 6.56E-11 1.85E-13 1.69E-12 81 211 "TTYH1,MTUS1,TMEFF1,ASCL1,TTC9B,FGF17,PRC1,INA,NOG,ADGRG1,RAB3C,JAM2,LHX2,ACBD5,CRMP1,FEZ1,SCRN1,JAKMIP2,GSDME,OLIG1,ELAVL3,OLIG2,EPHB1,KATNAL1,FABP7,ZIC4,GORAB,FOXG1,CAP2,SLC37A3,STAU2,C15orf41,RUNDC3A,GLDC,PCSK1N,GPM6A,GPM6B,TDRKH,STMN2,GSTT2,SOX21,FRMD5,NIM1K,HES5,TUBB2B,LMO1,PACRG,CHIC1,MT3,SCG3,TAGLN3,NELL2,NFIA,SLC10A4,GDAP1L1,GPSM2,SPATA6,MINDY2,PPP2R5E,NKAIN4,MAPK10,GDPD1,FEZF2,ADAL,LINC00461,MRAS,HSPA4L,SCG5,SH3GL3,SOX2,NPAS3,SPART,SYT11,CUX2,TCF12,TNNT1,RFTN2,XRCC4,ZIC1,ATP6V0E2,SHD" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k2 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.40E-14 7.13E-11 2.01E-13 1.83E-12 96 270 "EMILIN3,NDRG2,ADARB2,ADCY5,SORCS1,ADRB2,TMEM263,ASPH,ATP2B1,MYOM1,RAB3C,SLIT2,KIAA1549L,CNTN1,COL9A1,RTTN,FAM171B,PREPL,VCAN,PLCXD3,ZEB2,RABGAP1L,DMPK,EDNRB,RGS17,DCTN4,ENO2,EPHA5,ENPP6,NCALD,ETV1,RASL12,DLC1,MED12L,CAP2,EFCAB2,SORBS1,PDLIM5,PNMA2,DKK3,GFRA2,ZNF638,FERMT2,PRUNE2,ADAMTS8,BVES,SHISAL1,IGF1,RBPJ,IGSF1,KCNB1,KCNK3,KCNMA1,LIMS1,HECTD2,MBNL1,IL17D,MEF2C,MEIS2,NPTX2,NTRK2,CNTN3,PCDH9,PDE4D,ENPP2,NALCN,PRRX1,PRKAB2,DIRAS2,PSD,LGI2,KCNIP3,ATXN1,TNFRSF19,SH3BGR,SH3GL2,RIMS1,TNIK,LMO3,SMOC1,SYT1,AGTPBP1,EHBP1,SYNE1,HHIP,NACC2,TMOD1,TNNT1,RASD2,TPM2,RGMB,SYNPO2,TRPS1,SSBP2,PARP11,MSRB3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.41E-14 7.19E-11 2.02E-13 1.84E-12 120 369 "RALGAPA1,EMILIN3,USP31,TBC1D14,TAOK1,FAM135A,ANK3,APAF1,APC,PHYHD1,LGR5,CASK,SLC4A4,BARD1,BCHE,BMP7,CACNA2D1,CANX,CDC27,ZMYM4,SOCS6,FAM171B,PREPL,VCAN,TM9SF4,TMEM170A,ELMO1,MFAP3L,ARNT2,KBTBD11,DPYSL2,DYRK1A,EDNRA,EDNRB,HIPK3,SEMA3D,VPS13B,ETV1,EYA1,DLC1,KIAA1109,SUCO,SMC2,CELF1,OGA,GABRA3,AHCYL1,IQGAP2,GFRA1,PCDH17,GHR,PPARGC1A,PCDH11X,FERMT2,RAPGEF4,GRIA2,GUCY1B1,RASSF8,KLF12,ZDHHC15,RBPJ,LIFR,LIMS1,MARK1,CHIC1,KITLG,PPM1L,MKLN1,MMP16,NASP,NFIA,PAK3,PDE3A,PDGFRA,TMOD2,PIK3C2A,PRRX1,FAT3,KANSL1,MAPK9,PTPRG,TMEM255A,REV3L,KLHL11,SETD5,RPE,LGR4,TNFRSF19,ZFP2,RUFY2,NAPB,ZHX3,MYCBP2,PEG10,KIF1B,CLASP2,TROVE2,SMOC1,EPB41L3,NEK4,FGD4,VPS13A,PJA1,DNMBP,CAMSAP2,AGTPBP1,FBXW11,TBL1X,CLASP1,NSD1,HHIP,ERCC6L2,RBFOX2,RGMB,TRIO,TRPS1,WRN,NUP214,ZNF248,MSRB3" Coexpression Atlas PCBC_ECTO_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.54E-14 7.86E-11 2.20E-13 2.01E-12 254 986 "KCNH8,AXIN2,ERMN,GRAMD1B,ADORA1,DPP10,APLP1,VAT1L,LGR5,LINC00173,ASCL1,RASL11B,ASTN1,KIF1A,BMP7,CA4,CABP7,CAMK2A,ISPD,CLDN10,CCK,SYNGR3,CDH8,CDH18,LGI1,NOG,ABCG2,FAM19A5,IGLON5,CNTFR,COL9A1,COL9A2,COL9A3,COL11A2,GAL3ST1,TCEAL2,TOGARAM2,NRG2,IGDCC3,HS3ST5,FAM171B,HAPLN1,LRRC3B,CNTNAP2,PLCXD3,GREB1,CTNND2,BOC,RIMS3,DGKG,TMEM130,LYPD1,SNAP91,KIF19,GRIN3A,HS3ST4,DNAH9,CDON,DPP6,EFNA2,ELAVL2,EMX2,CDHR1,TMEM74,ADGRV1,CLVS1,FABP7,TMEM132C,ZIC4,SPSB4,ATP13A4,B3GAT1,TVP23A,PHYHIPL,GABRA2,CHL1,ILDR2,SALL3,GAP43,SYT17,GLDC,AIFM3,PRUNE2,GPM6A,LPAR4,GRIA1,GRIA4,GRM2,GRM3,GRM7,GUCY1B1,CELF3,UBE2QL1,IGSF21,HAPLN2,IGFBPL1,C9orf129,SHISA6,CELF5,ATCAY,IRF8,BTBD17,PLD5,IGSF1,HES5,LIX1,SLC6A17,INSM1,TUBB2B,ZNF385B,LRRTM1,ITGA7,ITPKB,KCNA1,OLFM3,KCND1,KCND2,KCND3,KCNJ4,KCNN3,KCNQ2,KIF5C,LRRC4B,LMO1,CLEC18A,MAP2,MAP6,WDR49,SAMD5,SESN3,BCO1,SCG3,DDX25,RSPO2,MYO7A,TCEAL5,NELL1,NELL2,NHLH1,NNAT,NPY,NTRK3,IGSF11,KCNK10,CNTN3,PAX6,PRTG,PDE1B,ENPP2,HMGCLL1,ASPDH,SDK2,NECAB2,FA2H,POU3F2,NKAIN4,VSTM2L,RAB39A,PROX1,RELN,KLK6,LAMA1,GDPD2,STK32A,PTPRD,STRC,TMEM255A,FEZF2,KHDRBS2,PRRT2,RFX4,RGS7,RLBP1,ZFHX4,KLHDC8A,MELTF-AS1,HUNK,YJEFN3,KCNIP1,FAM182A,LRFN5,SLC30A10,TMEM200C,SCG5,ARX,SLC1A6,PKNOX2,LRRC55,SLIT1,DMRTC1,RIMS1,CABCOCO1,UNC80,SOX3,SOX10,SOX15,NMNAT2,LHFPL4,SPTB,LMO3,CLSTN2,COLGALT2,STOX1,SST,SOX21-AS1,ZFR2,TAC1,UNC5D,CNTN2,VWA3A,VWC2,PCDHGB6,PCDHB15,PCDHA6,PCDHA3,PCDHA2,RNF175,DICER1-AS1,THBS4,ICAM5,NR2E1,RIMBP2,DOK6,PPIL6,FNDC5,CA14,TTPA,TMEFF2,CLEC2L,FAM181B,ZNF709,VGF,TSPAN11,RBFOX3,ZIC1,ZIC2,ZIC3,KCNT2,EMX2OS,CRB2,DPYSL5,ANKS1B,LAMP5,CA10,CADM2,STMN4,XKR7,GAL3ST3,DNAH10,DOCK8,FAM182B,ADAMTSL3,FAM181A,JPH3" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000 dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.66E-14 8.46E-11 2.36E-13 2.16E-12 216 804 "ABAT,CSMD3,FMNL2,SLITRK1,ADD3,AXIN2,MTA3,KLHL13,NME5,NR0B1,ARHGAP20,KCNT1,AMPH,OGT,SEMA7A,APOC1,SHTN1,LGR5,CDC14B,CDK10,SEMA4G,PPP4R4,TMEFF1,PDE8B,CAPRIN2,NUMB,INSYN2B,CCDC181,ATP2B3,RNF182,RGS11,DST,ST3GAL5,WASF1,MYRF,CACNA1D,CACNB2,CALB1,RGN,SLC16A4,REPS2,CDH2,DCLK1,CDH18,MAGI1,UBE2L6,ADGRG1,CHRM4,CLU,NMT2,AKAP5,ZNF521,LRRC3B,PLXNA4,PHF14,CTH,BOC,DOCK4,GPRASP1,DAPK1,MAGI2,FBXO25,SRGAP3,CDON,DOCK2,DPYSL2,DRP2,TSPAN5,RASGRP1,KLHL5,FAM13A,MRO,ABI2,PLXNC1,CERCAM,TMEM35A,EMX2,EPB41L1,MTSS1L,NRN1,FAM198B,AFF2,CAMKK2,NSG1,GABRA4,GABRB1,TRAF3IP2,GALC,GATM,SESN1,DHRS4,PCDH11X,GPD2,GPR37,GRIK3,GRIK5,KIF3A,RABL2A,PACSIN2,ELOVL5,TCEAL6,SHISA6,IDH3A,IGF1,NKD1,PLD5,IL6ST,SLC35G1,KCND2,KLHL23,SYTL4,ARHGAP12,MAOB,MAP2,MATN2,MEIS1,KITLG,SCAMP5,AFF1,MOV10,SESN3,CCDC80,MTR,LAYN,MYO9A,NEXMIF,NFIA,NNAT,NOS1,NPR2,SLC11A2,NUCB2,OPHN1,ETFRF1,PDE1A,CDK14,SERPINI1,SEMA5B,PIK3C2A,PCDH18,PPARA,PPP3CC,GDPD1,CNNM2,GDPD2,CNTLN,PTPRG,FAT4,TSPY26P,REV3L,RGS10,RNASEL,ZFHX4,TMEM206,RPS6KA2,LGR4,PTGR2,MEG3,HUNK,CCDC112,SEMA6D,PRCD,TNFRSF19,STUM,MRAS,RASA3,CNKSR2,ST8SIA1,ABLIM3,SLC4A3,SCMH1,SNCA,TNIK,KDM3A,UHRF1BP1L,ERC1,PEG10,ARHGAP26,TSPYL2,LHPP,SMOC1,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,SZT2,DOCK9,OBSL1,CCDC173,TEX15,DNAH7,ZFPM2,GZF1,ACTR6,DAAM2,KAT6B,TNNT1,FNDC5,DCBLD1,TST,UCHL1,CCDC136,VAV2,ZNF23,ELFN1,LYPD6,REEP1,ZFAND5,ADAMTS9,TMEM178A,NAV2,WNK3,KLHDC1,FRMD6,DPF3" Coexpression Atlas PCBC_SC_blastocyst_500 Progenitor-Cell-Biology-Consortium_StemCell_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 2.13E-14 1.09E-10 3.03E-13 2.76E-12 149 497 "SYN3,TMEM132B,ADCY2,ADD2,UNC5A,NLGN4X,PDZD4,RASL11B,KIF1A,LDHD,SYT6,MAP7,CLDN10,CHGA,RAB3C,DLGAP3,FAM19A5,IGLON5,COL9A1,GAL3ST1,TCEAL2,HS3ST5,ATRNL1,NCAN,RIMS4,CNTNAP2,SEC14L5,RIMS3,BRINP1,CALN1,FAM57B,DPP6,ST8SIA3,AASS,LINC00599,SEZ6,CDHR1,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,GRM3,LINGO1,TMEM179,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,KCND2,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,MATK,CHST6,CPNE9,SCG3,DDX25,FXYD7,NELL2,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,EPB41L4B,PACSIN1,PPP2R2B,NKAIN4,RAB39A,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,RIMKLA,HUNK,RYR1,SALL1,TMEM200C,SH3GL2,PPM1E,SLC1A6,SLC8A2,TMEM132D,SLCO1A2,IGSF9B,SNCB,SNRPN,SOX3,LHFPL4,SEPT3,ACSBG1,ABCC8,ZFR2,ARC,COBL,SYT4,TAC1,TAC3,UNC5D,TMEM151B,CHST8,GALNT17,ENHO,TLL2,ANKRD24,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,SLC30A3,CADM2,GAL3ST3,JPH3" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K4 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 3.25E-14 1.66E-10 4.60E-13 4.19E-12 46 90 "TTYH1,SHTN1,ATP2B2,DIRAS1,HAP1,DNAJB5,NCAN,SLITRK5,DTNA,ELAVL3,OLIG2,EPHB1,APC2,ADGRV1,REEP2,TUBB3,NSG2,DLL3,SRRM4,STMN2,GRIK2,RNF165,CELF3,TOX2,FRMD5,IGFBPL1,HES5,MAP2,NRCAM,POU3F4,GAL3ST4,CCDC112,HSPA4L,SCG5,SOX5,SEPT3,SYT11,FGD4,TCF4,TUB,MGAT5B,ZIC3,DPYSL5,SHD,FZD3,SPATA13" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k2_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.25E-14 1.66E-10 4.60E-13 4.19E-12 46 90 "APLP1,ASCL1,INA,LHX2,CRMP1,CSNK1E,GSDME,ELAVL4,FABP7,TUBB3,DPYSL4,DLL3,GAP43,TOX3,KIAA1958,GNG3,STMN2,BACH2,INSM1,TUBB2B,KLC1,MAPT,TAGLN3,NEFM,NNAT,GNG2,ZIK1,NKAIN1,GAL3ST4,ZFHX4,ATAT1,SCG5,SNAP25,SNRPN,SOX2,SOX5,SOX11,GSE1,SYT11,TRIM2,CLASP1,ZIC1,ZIC3,MEIS3,PCBP4,VANGL2" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_1000 DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.69E-14 1.88E-10 5.19E-13 4.73E-12 215 805 "ARID1A,SLITRK1,RNF157,ADD1,PNMA8B,PWWP2A,INTS2,KLHL13,NR0B1,AK2,TAOK1,ARHGAP20,LCORL,PKP4,ASPH,INSYN2B,ATP2B1,RNF182,DOCK11,BACH1,FUBP1,SGCE,BTRC,CALB1,RUNX1T1,CDH2,CDH10,ZNF445,SRSF11,SOCS6,CHM,SLIT2,PLAA,NMT2,QKI,CNR1,COL4A5,AKAP5,RBM39,HAPLN1,TENM4,FAM169A,DZIP3,GREB1,PUM1,DOCK4,FGFR1OP2,GAPVD1,TCAF1,MATR3,KIAA0586,AIF1L,DCT,ZEB2,ZC3H11A,GSDME,ALKBH8,G3BP2,CDON,DRP2,ABCC5,EDIL3,EDNRA,PLXNC1,EIF4G1,ELAVL2,TMEM35A,CALCRL,EMX2,EPB41L2,SRRM1,FAM198B,SCML2,ATP8A1,CHST15,PRMT5,KIAA1109,MEX3B,ANKFY1,SMC2,APOPT1,FYN,GABRA4,GABRB1,ILDR2,TUBGCP4,SRCAP,BRD8,PCDH11X,LPAR4,GPR37,DIDO1,GRIK1,CIT,KIF3A,FAM19A2,MAEL,MIER3,INSM1,KCND2,MAP4,CHIC1,MEIS1,MEIS2,KITLG,MID1,MMP16,SAMD5,MSI1,MYBPC1,MYCN,NEXMIF,NAP1L2,NASP,NEFM,NFIA,CNOT4,PCDH9,PDE1A,PDPK1,GPR85,OLA1,SERPINI1,PIK3R1,JAKMIP1,RC3H2,PRRX1,PPP2R5E,KANSL1,MAPK8,PTN,PTPRG,TMEM255A,C1orf54,MSANTD2,RFX3,PBRM1,RNASEL,ZFHX4,TMLHE,ROBO2,PCMTD2,MEG3,NCBP3,SATB1,CSRNP3,ATXN2,FNIP1,STUM,SFPQ,TRA2B,ARX,CHD9,FNDC3A,SYBU,WDR37,SLC12A2,SCMH1,SPHKAP,TET1,CPEB4,ZKSCAN3,SMARCA4,SNCA,SOX2,SOX5,ZCCHC24,ZC3H13,KIF1B,RBM26,TROVE2,LARP4,RGL1,PRRC2C,SYNE2,SLC37A2,ANKRD12,KLHL4,DMXL2,CLASP1,OBSL1,AHCYL2,SIRT1,CBX5,ACTR6,ASXL3,R3HDM1,TPM1,NR2C2,TRPS1,TSC1,SSBP2,UBE3A,FLRT2,TBC1D15,VSNL1,NSD2,RICTOR,PCDH20,ZFP37,ZIC3,ZNF711,ZNF23,TRIM9,EMX2OS,REEP1,ADAMTS9,NAV2,SNX27,KCNAB1,FIP1L1,JMJD1C,ZDHHC20,GAN,SENP7" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_250 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_250 FaceBase_ST1 3.76E-14 1.92E-10 5.29E-13 4.82E-12 70 173 "ACADM,ERMN,PCDH19,TAOK1,ABCD2,APBA2,ASCL1,TTC9B,INA,JAM2,LHX2,RAB33A,FEZ1,CNTNAP2,TOX,SCRN1,JAKMIP2,SRGAP3,DLX1,ELAVL3,FABP7,FOXG1,EFCAB2,GAD2,KIAA1841,GLDC,GPM6A,GPR19,UBE2QL1,USP51,HES5,INSM1,TUBB2B,LRRTM1,LMO1,MT3,SCG3,LYRM9,MYO9A,NELL2,NFIA,NOVA1,PAK3,PAX6,SLC10A4,SCHIP1,MINDY2,PKIA,GDPD1,PTX3,TUG1,PBRM1,LINC00461,HSPA4L,SCG5,KIF21A,SLC4A3,TET1,SOX2,NPAS3,SLC35G2,CCDC173,NR2E1,FAM181B,XRCC4,PMEPA1,STOX2,PARP11,AMN1,NETO2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.90E-14 1.99E-10 5.47E-13 4.98E-12 74 188 "SORCS2,C1QTNF3,ARHGAP20,SYT13,CASK,DOCK11,IL33,CACNA2D1,RUNX1T1,LDB2,REPS2,CDH2,CDH10,RCBTB2,ZNF521,FAM171B,RNF14,NCOR1,BOC,RASSF2,SRGAP3,NTM,EBF1,EDIL3,SEMA3D,TMTC1,EGFR,PLXNC1,ELAVL2,GAB1,GHR,GLI2,GLRB,RAB40B,GRIA1,GRIA4,UBE2QL1,KLF12,IGF1,KCND2,VWA5A,MAP2,MEIS1,MEIS2,MN1,MTR,DDR2,PDGFRA,GPR85,PIK3R1,FTO,PCDH18,PTPRD,FAT4,RBBP6,TSPY26P,ZFHX4,MEG3,SATB1,CSRNP3,FAM19A1,NTNG1,DZIP1,MAPKBP1,PDZRN3,TROVE2,ADGRL3,KLHL4,PCDHB7,TEX15,SSBP2,RTN4,SSPN,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.30E-14 2.19E-10 6.01E-13 5.48E-12 104 307 "ASIC2,ADCY2,SRPX,FAM135A,LRCH2,APAF1,RNF182,RUNX1T1,CDC27,CDH2,CDH10,SYNPR,ZNF521,AKAP12,NCOR1,SOCS5,APPL1,BOC,AK5,CCDC3,DNM1,EBF1,EDIL3,ABI2,PLXNC1,ASB3,MRVI1,ARMCX1,ATP8A1,FER,OLFM1,UBE2E3,NSG1,GAB1,DNER,FREM1,GGTA1P,PCDH11X,RAB40B,CACFD1,MAP4K5,IRAK3,KLF12,NEGR1,AGFG1,METTL21A,KIF2A,LSAMP,MEF2C,MEIS1,MEIS2,MEST,MMP16,MN1,MYO5A,DDR2,PBX1,PDGFRA,ANLN,LRP12,SH3KBP1,PPP3CA,GRAMD1C,CNTLN,ZIK1,PTPRD,PTX3,FAT4,ARID4A,RBBP6,CRTAC1,SLC25A36,KIRREL1,CCDC112,SCN2A,TRA2B,DOCK10,NTNG1,DZIP1,WDR37,TET1,CXXC4,KIF1B,ELOVL4,NEK4,TTBK2,KLHL7,ADGRL3,ANO4,ZEB1,PCDHB3,ASXL3,TRO,TTPA,AMOT,FLRT2,ZBTB14,MKRN3,CELF4,GOPC,FAM13C,CERS6,SOCS4,ST8SIA2" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.78E-14 2.95E-10 8.05E-13 7.34E-12 212 794 "ACTN1,KDM5D,KLHL32,ADCYAP1R1,PNMA8B,GRAMD1B,KLHL13,NR0B1,SORCS2,SPARCL1,ALCAM,ARHGAP20,LTBP4,AMH,GAS7,GPAM,LGR5,CDC14B,PPP4R4,IGDCC4,CADPS,DDX3Y,TMEM108,SLC4A4,CACNA1G,MYRF,CACNA2D1,ISPD,RUNX1T1,PRC1,ARHGEF25,CBLN1,LDB2,REPS2,CDH10,DCLK1,SLIT2,CLU,CNTFR,AKAP5,MAGED1,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,VCAN,PLXNA4,PLCXD3,BOC,DOCK4,RIPOR2,SCRN1,ARMCX2,DCT,ZEB2,SV2A,SRGAP3,DNM1,DRP2,DTNA,MAMLD1,E2F6,TSPAN5,EDNRA,HEYL,SEMA3D,EGFR,MRO,PLXNC1,SORBS3,C8orf37,EMX2,LRRC17,MTSS1L,EPS8,ERBB4,EYA1,ARMCX1,FAM198B,FABP7,PTK2B,TUBB4A,DLC1,RACK1,FGF13,FOXM1,FLNC,AFF2,NSG1,FYN,GABRA1,GABRA4,TRAF3IP2,NEK6,SEPT9,GATM,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,PSRC1,GPM6A,GPM6B,GPR37,GRIA4,PRDM5,FAM19A2,GUCY1A2,GUCY1A1,KLF12,HPSE2,TCEAL6,LRRTM3,KCND2,KCND3,KCNH1,KLHL23,LAMA2,MAP2,MATN2,MEF2C,MEIS1,MOV10,DDX25,NCAM1,ZC3H12B,NFIA,NNAT,NME4,PAK3,PCDH9,PCSK5,PDE1A,PDGFRA,PGAM2,SERPINE2,ANLN,PCDH18,PLTP,FAT3,SH3KBP1,LRRN3,RASGEF1B,PRKCB,MASP1,LAMA1,PTCH1,PTN,PTPRD,TMEM255A,ZCWPW1,RADX,REV3L,RAVER2,ROBO1,ROBO2,TMEM206,ARMH4,GLDN,ACER3,LGR4,MEG3,ZNF354C,SOX6,MRAS,RASA3,ARX,DOCK10,NTNG1,ST8SIA1,SLC4A3,SMTN,PKNOX2,SEPHS1,SORCS3,PALLD,PDZD2,TNIK,ZCCHC24,ZNF423,SPART,SMOC1,ZC4H2,ST5,SULF2,ARHGEF9,PJA1,ADGRL3,ZEB1,PSD3,OBSL1,ZFPM2,TGFBR3,HHIP,THRA,BEX4,TPM1,KCNE5,SSBP2,TMEFF2,PLEKHH2,VSNL1,ZFP37,STOX2,ADAMTS9,WNK3,NETO2,ST8SIA2" Coexpression Atlas ratio_SC_vs_MESO_500_K5 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 5.96E-14 3.04E-10 8.28E-13 7.54E-12 101 296 "VAT1L,SYT6,CLDN10,DCLK1,CHGA,RAB3C,NRXN1,PCYT1B,HS3ST5,LRRC3B,RIMS4,FAM131B,SEC14L5,HDAC9,TOX,PHYHIP,JAKMIP2,PARD6A,RABGAP1L,CHRDL1,HS3ST2,FAM57B,CACNG7,AASS,LINC00599,ANKRD13B,ETV1,PIPOX,FABP7,PPP1R1B,OLFM1,FLT1,NSG1,GLDC,TOX3,GNAO1,GNG3,GNG4,LPAR4,GRIA4,GRM3,LINGO1,C1orf94,HRH3,ATCAY,BTBD17,IGSF1,LRRTM3,KCND2,KCNN2,KHK,KIF5A,CAMK2N2,FGFBP3,CPNE9,SCG3,FXYD7,NAP1L2,NELL2,NOVA2,NPTX2,NTRK3,ZDHHC22,PAH,PCSK1,GDAP1L1,CAMKV,PLP1,GDPD2,PTPRZ1,TMEM145,RGS7,RIT2,RORB,RIMKLA,RYR1,PPM1E,BCAN,NLGN1,SNCB,SOX2,NMNAT2,LHFPL4,SPP1,RHBDL3,ARHGEF9,ARC,SYP,SYT1,ACSL6,TMEM151B,SLC19A3,PCDHAC2,FBXL16,ENHO,TLL2,ANKRD24,VGF,VSNL1,LAMP5,TMEM63C" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.51E-14 3.32E-10 9.02E-13 8.22E-12 123 389 "FMNL2,ADCY2,AXIN2,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,LRCH2,LRRC4C,LGR5,CDC14B,INSYN2B,SLC4A4,ATP2B3,MYRF,CACNA1D,CALB1,REPS2,CDH10,DCLK1,MAGI1,SLIT2,CNTFR,AKAP5,ZNF521,TENM4,ATRNL1,VCAN,PLXNA4,BOC,DOCK4,DAPK1,MAGI2,SV2A,SRGAP3,DNM1,CDON,DRP2,TSPAN5,EDNRA,KLHL5,PLXNC1,EMX2,LRRC17,NRN1,FABP7,KIAA1109,FLNC,AFF2,NOP56,GABRA4,GABRB1,DENND2A,GFRA2,FREM1,PCDH11X,ADGRA3,GUCY1A2,GUCY1A1,TCEAL6,NKD1,KCND2,KLHL23,MAP2,MATN2,MEIS1,KITLG,SESN3,CCDC80,MTR,MYO9A,NCAM1,NEFM,NELL1,NFIA,NME4,PDE1A,PDGFRA,CDK14,PCDH18,PRRX1,LAMA1,GDPD2,PTN,TMEM255A,FAT4,RNASEL,ZFHX4,TMEM206,LGR4,MEG3,HUNK,SEMA6D,SCN2A,PRCD,TNFRSF19,STUM,RASA3,ST8SIA1,SLC4A3,PALLD,KDM3A,UHRF1BP1L,PEG10,SMOC1,ST5,ADGRL3,SZT2,PSD3,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,TNNT1,TRPS1,TST,FLRT2,VSNL1,LYPD6,ADAMTS9,WNK3" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 7.18E-14 3.66E-10 9.92E-13 9.04E-12 42 79 "SLITRK1,ASTN1,ATP2B2,JAZF1,HAP1,ADGRG1,IQCK,ST18,KATNAL2,TOX,JAKMIP2,DLX1,MAMLD1,ELAVL4,FOXG1,SRRM4,KIAA1841,PCDH11X,PCLO,GRIK2,MFSD2A,IGFBPL1,INSM1,MAP2,SHC3,ADAM22,MYT1,GPR137C,PAX6,ELOVL2,ENOX1,FEZF2,RFX4,LINC00461,SCG5,LMO3,ROBO3,NR2E1,UCHL1,ZNF23,STMN4,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl1_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.41E-14 3.78E-10 1.02E-12 9.31E-12 40 73 "TTYH1,NDRG2,SPARCL1,ATP1A2,BMP7,CDO1,JAM2,IGDCC3,TENM4,NCAN,LYPD1,EDNRB,EFNB3,ADGRV1,FABP7,C1orf61,PDLIM5,GPM6B,SCRG1,HES5,FGFBP3,NRBP2,RSPO2,MXI1,NFIA,NTRK2,PMP2,FAT3,PTN,PTPRO,PTPRZ1,KLHDC8A,BCAN,SLC1A3,ITPRID2,SULF2,TCF12,PSD3,HEY1,LRP8" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 8.06E-14 4.11E-10 1.11E-12 1.01E-11 146 491 "PLEKHG5,USP31,PTCHD1,MARCH4,GPRASP2,AMPD2,APOC1,CPNE5,LGR5,SEMA4G,MADD,IGDCC4,RGS20,ATP1A3,BARD1,GPC2,LDLRAD4,CA12,CACNA1A,CACNB2,HAP1,MAP7,CDC25B,CDH18,NRXN2,MYL6B,CNTFR,PCYT1B,LETMD1,CRYBB1,CLIP3,CSF2RA,ATRNL1,ST18,DNAL1,C8orf34,SV2A,SRGAP3,RABGAP1L,ARNT2,ACOT8,MBNL2,ELAVL4,APC2,TESK2,BAIAP2,FOXG1,ZMYND15,SGIP1,NBEA,NPTN,TMEM151A,GAD2,ARPP21,HIGD1B,SRRM4,FAXC,GFRA1,RAB30,PCDH11X,STARD3,LOXL3,PCLO,RAPGEF4,GRIK2,WIF1,FRMD5,HLF,HPSE2,TCEAL6,CELF5,ATCAY,IGF1,IGSF1,ZNF385B,LRRTM1,KCNA6,KCNH2,L1CAM,LSAMP,SMAD9,MAP2,KITLG,MOBP,CPNE9,SAMD5,N6AMT1,HS6ST3,MXI1,MYH3,NPY,NUCB2,PAK3,PAX6,PDE3A,PDE4D,PENK,PFKFB2,GDAP1L1,SERPINE2,ZFYVE21,DIRAS2,MASP1,TMEM231,RALGDS,RAP1GAP,GAL3ST4,PRRT2,MORC4,TMEM100,SCG5,NTNG1,CNKSR2,SLC1A3,SORCS3,SNAP25,DOP1A,SOX2,TNIK,UNC5B,ARHGAP26,CDK19,C11orf87,NKAIN2,SEPT3,ARHGEF9,PLCB1,ANKRD12,KAZN,PHF24,HIF3A,LEFTY2,SLC44A1,NACC2,NR2E1,ANKRD24,PRMT8,STXBP4,UCHL1,MGAT5B,PLPPR2,CCDC136,NPDC1,ZNF23,CERS6,SENP7" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K3 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 8.51E-14 4.34E-10 1.17E-12 1.06E-11 68 168 "GALNT16,CCDC85A,WDR35,LTBP4,GPRASP2,CDC42BPA,PHYHD1,ASTN1,CCDC181,DDR1,DIRAS1,LONRF2,KIAA1549L,NRXN1,SLC35F1,CREB5,FEZ1,RUBCN,TOX,RUSC2,FBXO25,DMD,SHANK1,TMEM35A,EPHA5,CHST15,CAP2,DPYSL4,NRG3,PPARGC1A,MFSD2A,CELF5,MGAT3,NEXMIF,NCAM2,NELL2,NFIA,NFIX,PCDH9,NLGN3,TMEM38A,POU6F1,MDGA2,PTPRZ1,PBRM1,ARMC5,MEG3,ATXN1,LRRTM4,FHOD3,NLGN1,YPEL4,SMARCD3,NPAS3,CLSTN2,ANKRD12,SEMA4A,KIAA1107,PSD3,TRPC3,KCNE5,TUBB2A,CCDC136,TSPAN11,RBFOX3,NPDC1,FMN2,SENP7" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-episomal_cfr-2X-p05 Mesoderm Day 30-method_NA_vs_Mesoderm Day 30-method_episomal-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.75E-14 4.97E-10 1.33E-12 1.21E-11 79 210 "TTYH1,SERPINA3,ARSE,ATP1A3,CDK5R1,GPC2,INA,ARHGAP33,LARGE1,CDO1,LHX2,IGFBP7-AS1,TMEM59L,AKAP7,CRMP1,FEZ1,LYPD1,CCDC3,USH1C,CACNG7,ELAVL3,FABP7,KHDRBS3,NSG2,GAP43,DNER,GJB1,TOX3,PCSK1N,GNG4,GPM6A,LINGO1,CELF3,IGFBPL1,ATCAY,HES5,ITIH2,KCNJ16,KIF5A,KIF5C,L1CAM,LRRC4B,PIK3AP1,MAOB,MAPT,MTTP,NCAM1,NELL2,NPPA,GNG2,SERPINE2,SEMA5B,RELN,PTN,PTPRZ1,NKAIN1,RAP1GAP,PRRT2,MYH14,RTN1,HES6,IL17RB,HKDC1,SLC12A2,SLIT1,KIF21B,SOX11,BEX1,SST,SEPT3,ROBO3,ANO4,SLAIN1,ZIC2,ZIC3,DPYSL5,STMN4,SCG2,PANTR1" Coexpression Atlas PCBC_ratio_MESO-30_from-ESC_vs_MESO-30_from-OSK-L-l-p53KD_cfr-2X-p05 Mesoderm Day 30-reprogram_NA_vs_Mesoderm Day 30-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.75E-14 4.97E-10 1.33E-12 1.21E-11 79 210 "TTYH1,SERPINA3,ARSE,ATP1A3,CDK5R1,GPC2,INA,ARHGAP33,LARGE1,CDO1,LHX2,IGFBP7-AS1,TMEM59L,AKAP7,CRMP1,FEZ1,LYPD1,CCDC3,USH1C,CACNG7,ELAVL3,FABP7,KHDRBS3,NSG2,GAP43,DNER,GJB1,TOX3,PCSK1N,GNG4,GPM6A,LINGO1,CELF3,IGFBPL1,ATCAY,HES5,ITIH2,KCNJ16,KIF5A,KIF5C,L1CAM,LRRC4B,PIK3AP1,MAOB,MAPT,MTTP,NCAM1,NELL2,NPPA,GNG2,SERPINE2,SEMA5B,RELN,PTN,PTPRZ1,NKAIN1,RAP1GAP,PRRT2,MYH14,RTN1,HES6,IL17RB,HKDC1,SLC12A2,SLIT1,KIF21B,SOX11,BEX1,SST,SEPT3,ROBO3,ANO4,SLAIN1,ZIC2,ZIC3,DPYSL5,STMN4,SCG2,PANTR1" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.76E-14 4.98E-10 1.33E-12 1.21E-11 129 417 "RNF157,PNMA8B,PWWP2A,INTS2,TAOK1,LCORL,PKP4,BACH1,CALB1,RUNX1T1,CBLN1,CDH2,CDH10,DCLK1,ZNF445,CHGB,SOCS6,CHM,SLIT2,COL9A1,RBM39,CRMP1,HAPLN1,PUM1,ST18,DOCK4,FGFR1OP2,TCAF1,AIF1L,ZNF804A,ZEB2,ZC3H11A,GSDME,EBF1,EDIL3,EDNRA,EIF4G1,ELAVL2,ELAVL4,EMX2,SRRM1,FABP7,TUBB3,PRMT5,MEX3B,SMC2,APOPT1,NSG2,MEGF10,GAP43,DNER,TUBGCP4,PCDH11X,LPAR4,STMN2,FAM19A2,INSM1,CHIC1,MEIS2,KITLG,MMP16,MSI1,TAGLN3,MYBPC1,NAP1L2,NASP,NEFM,NEUROD1,PCDH8,GPR85,SERPINI1,PRRX1,MAPK8,PTX3,CEP97,C1orf54,FIGN,RFX3,RGS4,PBRM1,ZFHX4,TMLHE,ROBO2,PCMTD2,MEG3,CSRNP3,DRAXIN,LINC00461,SFPQ,TRA2B,ARX,SLC1A3,PREX2,SLC12A2,SCMH1,SPHKAP,CPEB4,ZKSCAN3,SMARCA4,SNAP25,SOX2,ZC3H13,KIF1B,RBM26,TROVE2,CLSTN2,RGL1,SYNE2,KLHL4,AHCYL2,CBX5,ACTR6,ASXL3,R3HDM1,RBFOX2,TPM1,NR2C2,SSBP2,FLRT2,NSD2,PCDH20,ZIC1,ZIC3,ZNF711,TRIM9,ADAMTS9,SNX27,GAN,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.12E-13 5.70E-10 1.52E-12 1.38E-11 27 38 "SYT13,ANK2,ANK3,CHGB,ELAVL3,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,GAP43,GNG4,STMN2,CELF5,BEX5,PCSK1,PPP2R2B,PTPRN,RTN1,SCN2A,SNAP25,SCN3B,SYT4,DNAJC12,VGF,CELF4,SCG2" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K1 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.19E-13 6.09E-10 1.62E-12 1.47E-11 229 881 "EMILIN3,ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,HECW2,RTL9,KIAA1324,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,CDK10,SEMA4G,IGDCC4,SPTBN4,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,NRP2,ZNF599,SCAPER,C1QC,CACNA1G,GPC2,LDLRAD4,CACNA2D1,RUNX1T1,REPS2,KCNAB3,CDH18,CDO1,CCPG1,CRLF1,UBE2L6,CLU,VAX2,COL9A2,COL9A3,ABI3BP,ENTPD4,CRYBB1,ANKRD44,CLIP3,SNCAIP,CSF1R,SUSD5,ATRNL1,PLCH2,BOC,DGKG,TIAM2,CCDC3,DLG2,GRIN3A,DNM1,USP3,DRP2,ABCC9,SNX29,TMTC1,MBNL2,RASA4,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,EPS8,DENND4A,PTK2B,FCGRT,FDFT1,TESK2,SCARA3,SGIP1,TRIM16,DLL3,STAU2,TMEM151A,ABLIM2,TVP23A,FYB1,ZMAT1,DKK3,ARPP21,TMEM8B,CPLX2,NEU3,FREM1,GHR,LYVE1,ZNF276,RAB30,GNG4,GRK4,GRIA1,GRIK4,GSN,TMEM25,GUCY1B1,WIF1,SYNPO,ICA1,SCIN,IL11RA,ZNF385B,ITPKB,JAK2,KCNA6,KLHL23,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,GPR155,MAN2A2,MID1,MITF,MOBP,CPNE9,MSR1,N6AMT1,RSPO2,MYH3,TCEAL5,FXYD7,NELL1,NFIA,NFIX,NPY,NPR2,CLEC9A,NRGN,OPCML,ZNF827,CNTN3,PDE3A,PDE4D,PIRT,PFKFB2,CDK14,PLCL1,TRHDE,PRRX1,SDK2,EPB41L4B,PILRA,NXPH1,CCDC144B,CRLS1,PRKAR1B,DIRAS2,MASP1,GDPD2,CNTLN,ACSS3,RALGDS,IQSEC3,FAT4,RAP1GAP,ZCWPW1,ZNF493,BEND5,VEPH1,ZMAT4,MORC4,PRIMA1,ZFHX4,MYH14,MRAP2,LRRK2,DGLUCY,ATXN1,LRFN5,MRAS,SGK1,SH3GL2,SH3GL3,ASAP3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC1A2,SLC6A9,SLC8A1,SMARCC2,ARHGAP26,IQSEC2,CDK19,C11orf87,EPB41L3,NKAIN2,ACSBG1,ARHGEF9,TACR1,KAZN,UNC5D,ADGRL3,TMEM136,TBX15,TCF4,SATB2,SYNE1,PHF24,FAM189A1,HIF3A,PIK3R5,SYNPO2,LRRC24,TRPS1,RFTN2,TSPAN11,ZNF32,LAMP5,PMEPA1,CADM2,PCDH15,CERS6,SSPN,DPF3,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.31E-13 6.67E-10 1.76E-12 1.61E-11 249 979 "EMILIN3,ACTN2,NDRG2,ADCY2,SLITRK1,RNF157,DISP3,ARHGAP20,LTBP4,GPRASP2,ANK1,PPFIA2,PHYHD1,APOC2,USP37,CDK10,SPTBN4,ASTN1,ADAM23,ADGRB2,ZNF599,BMPR1B,C1QC,CACNA1G,LDLRAD4,CACNA2D1,DIRAS1,VSTM2A,CDK11B,LRBA,REPS2,LONRF2,KCNAB3,CDH8,CDO1,CRLF1,ADGRG1,SRSF11,KIAA1549L,NRXN1,FAM149A,COL9A1,ABI3BP,IGDCC3,CREB5,CRYBB1,ANKRD44,CRYM,AATK,CSF1R,FEZ1,PLCH2,DZIP3,PHF14,ST18,NOS1AP,HDAC9,TOX,SCRN1,SPOCK2,JAKMIP2,RUSC2,GSDME,DDX46,CCDC3,DLG2,DLX1,DMD,SHANK1,CASP8AP2,DTNA,DUSP9,MAMLD1,SYT15,HEYL,SEMA3D,EGFR,RASA4,ELN,TMEM35A,EPB41,EPB41L1,LRRC17,EPHA5,EPS8,APC2,NSRP1,TMEM132C,CHST15,FCGRT,FGF11,AFF2,DPYSL4,ZCCHC17,SMC2,TRIM16,B3GAT1,NRG3,FYB1,JPH4,ARPP21,TMEM8B,PCDH17,PPARGC1A,ZNF276,GLRB,PCDH11X,ZNF638,MAP7D2,ADAP1,CECR2,NR3C1,GSN,MFSD2A,RABL2A,FAM107A,WIF1,FRMD3,SYNPO,USP51,NEGR1,KNDC1,LRRCC1,LIX1,IL11RA,BRINP3,KCNJ5,CREG2,KIF5C,KIT,VWA5A,IL17D,TM6SF1,MEIS2,SRSF12,MOBP,CD200,CCDC80,TAGLN3,RSPO2,NEXMIF,TCEAL5,NASP,NCAM2,NELL2,NFIA,NFIX,NRGN,ODF2,CNTN3,PCDH9,PDE1A,SEMA5B,TMEM38A,PLCL1,FXYD1,PRRX1,MAGEL2,NXPH1,POU6F1,CRLS1,PRKAR1B,DIRAS2,PRODH,MDGA2,PSMD13,STRC,RAB3A,ACSS3,RAP1GDS1,ZCWPW1,ENOX1,RBBP8,ZMAT4,DUSP15,ZFHX4,MYH14,EMID1,MEG3,STX1B,DGLUCY,ATXN1,LRRTM4,SFPQ,SH3GL3,FERMT1,ASAP3,DOCK10,NTNG1,FHOD3,ST6GAL1,CNKSR2,NLGN1,SLC1A2,PREX2,PEX26,DHX30,SLC6A9,SLC8A1,CCDC88A,SMARCD3,LIMCH1,BDP1,SOX11,UHRF1BP1L,NPAS3,C11orf87,CLSTN2,ZFR2,RHBDL3,ADAMTS17,PLCB1,SEMA4A,ROBO3,MCF2L,TMEM178B,UNC5D,ADGRL3,SATB2,CUX2,PHF24,FAM189A1,PSD3,ITGB3BP,ASXL3,TMOD1,SYNPO2,TRPS1,KCNE5,CA14,FLRT1,USP1,TSPAN11,FMN2,LYPD6,ZNF184,SPIRE1,PMEPA1,CADM2,LRP8,PCDH15,NAV3,TMEM163,DNAH10,MRPL47,KLHDC1,DPF3,ST8SIA2,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.66E-13 8.48E-10 2.24E-12 2.04E-11 62 148 "ANK2,VAT1L,CADPS,NRP2,C1QC,INA,DCLK1,RAB3C,RAB33A,FEZ1,VCAN,PLXNA4,SCRN1,DLG2,EDNRA,ELAVL2,LRRC17,EYA1,FABP7,TUBB3,EFEMP1,NSG1,TPPP3,GAP43,IGSF5,GFRA2,GNAO1,GNG3,STMN2,HPSE2,LIX1,KIF5C,L1CAM,SYTL4,MATN2,TAGLN3,NCAM1,NEFM,NNAT,NTRK3,PDGFRA,SLC10A4,PENK,TMOD2,PMP22,PRRX1,FAT3,MAPK10,PRPH,EML5,RTN1,SCN2A,FAM19A1,SCG5,SNAP25,SCN3B,SST,SYT11,TMEFF2,CADM1,UCHL1,STMN4" Coexpression Atlas Arv_SC_fibroblast_2500_K2 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.81E-13 9.23E-10 2.43E-12 2.21E-11 277 1120 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY8,GALNT13,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,RASL11B,TMEM108,KIF1A,CARMIL3,ADGRB1,CACNA1G,HAP1,SYT6,BRSK2,MAP7,CLDN10,CCK,MTMR7,SYNGR3,CDH8,DLGAP1,CACNA2D2,CHGA,RAB3C,DLGAP3,NRXN1,SLC24A2,FAM189A2,FAM19A5,SULT4A1,CCDC151,IGLON5,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,NOS1AP,KATNAL2,KIF26A,RIMS3,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,PARD6A,CHRDL1,HS3ST4,CALN1,FAM57B,DPP6,USH1C,SEZ6L2,EFNA2,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,ZNF589,OLFM1,FGFR1,HPCAL4,C1orf61,FLT1,SYT3,CSPG5,B3GAT1,TVP23A,MEGF11,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,SRRM4,IGSF5,GCK,GDF1,TTBK1,GLDC,PCDH11X,KDM2B,GNAL,GNG3,GNG4,GPM6B,GPR19,LPAR4,CECR2,GRIA4,GRIK5,GRIN1,ADAMTS8,GRIN2D,GRM3,PTPN5,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,PADI2,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,HPCA,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,RIPPLY2,TUBB2B,KCNA6,KCND1,KCND2,KCNN1,KCNN2,KCNN3,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,FGFBP3,CHST6,MPP2,CPNE9,JAKMIP3,ADAM22,SCG3,DDX25,MYCN,TCEAL5,FXYD7,NAP1L2,NAP1L3,NEFM,NELL2,NNAT,NOS1,PCBP3,ZDHHC22,PAH,NLGN3,GDAP1L1,SEMA5B,CAMKV,JAKMIP1,PLP1,PURG,PSAT1,NECAB2,MAGEL2,PACSIN1,POU3F4,PPP2R2B,PPP2R2C,RAB39A,PRKCG,LAMA1,GDPD2,PTPRD,PTPRN,PTPRZ1,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,PTGR2,HUNK,RYR1,SALL1,TMEM200C,SH3GL2,PPM1E,SLITRK3,CNKSR2,SLC1A6,PREX2,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,TET1,MAST1,IGSF9B,SNCB,SOX3,KIF21B,NMNAT2,LHFPL4,HECW1,SOX21-AS1,SEPT3,ZFR2,RHBDL3,NUDT10,ARC,SYP,SYT1,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,PCDHA3,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,TNNT1,KCNE5,CA14,TTPA,CLEC2L,UGT8,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,DPYSL5,PLPPR5,CADM2,GAL3ST3,RGS7BP,TMEM63C,NETO1,AP3B2,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.97E-13 1.00E-09 2.63E-12 2.40E-11 48 100 "CCDC85A,PCDH10,LTBP4,GPRASP2,APLP1,ASTN1,ADGRB3,KIAA1549L,CREB5,FEZ1,CTNND2,TOX,RUSC2,NTM,KBTBD11,EDNRB,EMX2,ENO2,EPHA5,ADGRV1,ATP8A1,PPARGC1A,MAP7D2,TDRKH,TOX2,LRRC4B,NCAM2,NEFM,NELL2,PAX6,PCDH9,SEMA5B,POU3F4,POU6F1,RTN1,SMARCD3,SOX2,MAPK8IP3,WSCD1,SLAIN1,PLPPR2,ZIC1,FMN2,TMEM237,DPYSL5,WNK2,KLHDC1,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.12E-13 1.08E-09 2.83E-12 2.58E-11 175 629 "CLK4,ARID1A,RNF157,FAM135A,GPRASP2,PHF12,PKP4,APC,ARHGAP5,PDE8B,NUMB,ASTN1,BBS2,ARHGEF7,CACNA2D1,PTBP2,KRIT1,SLC16A4,CDK11B,CDH8,ZNF445,CCPG1,SRSF11,EPS15L1,ZFYVE9,KIAA1549L,COG1,HECTD1,NIPBL,IQCK,SLC4A7,TBPL1,IGDCC3,CREB5,CLIP3,CSNK1G3,PLCH2,FAM169A,PNPLA8,KATNAL2,TOX,TBC1D5,KIAA0586,JAKMIP2,CEP170,ZC3H11A,GSDME,DDX46,DMD,MAMLD1,DYRK1A,DNM1L,E2F6,KLHL5,EPB41L1,COQ7,MTSS1L,EPHA5,SRRM1,RTN3,NSRP1,WAC,SEC24B,KIAA1109,PRKAG2,SMC2,OGA,CAB39,HIGD1B,C15orf41,KIAA1841,ARFIP1,PPARGC1A,GLRB,GOLGB1,ADGRA3,DIDO1,CIT,GUCY1A2,HMGB1,USP51,HSF2,INSM1,CREG2,KIF5C,KTN1,LIMS1,MAN2A2,MEST,CD200,SAMD5,ADAM22,MSR1,RSPO2,NASP,NCAM2,NEK1,NFIX,ODF2,GPR137C,CNTN3,PAX6,PCDH9,PCMT1,PDE1A,SEMA5B,PRIMPOL,TRHDE,ING3,CEP41,DIRAS2,MDGA2,CNTLN,ELOVL2,NKAIN1,ENOX1,ARID4A,FEZF2,ZYG11B,RFX4,SETD5,PLPPR3,CLIP1,STX1B,ATXN1,SCP2,CASC3,TRA2B,KIF21A,NTNG1,CHD9,FNDC3A,NLGN1,FAM81A,EPN2,SEPHS1,TET1,SMARCC2,CDK5RAP2,SON,SPATA7,BDP1,SOX11,CAND2,RBM26,LMO3,DIP2A,STXBP1,ZC3H4,SYNE2,DNAJC9,TAF9,TBL1X,TCEA1,ZEB1,ARHGEF12,SIRT1,NR2E1,TMPO,TRO,STXBP4,ZKSCAN5,ZNF711,ZNF23,FMN2,ZNF142,WNK1,MAP3K12,LRP8,TMEM163,KAT6A,HNRNPA3,ZDHHC20,KLHDC1,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.41E-13 1.23E-09 3.21E-12 2.92E-11 80 217 "AXIN2,PCDH10,SYT13,TNRC6C,MIER1,CADPS,INSYN2B,RNF182,CH25H,RUNX1T1,CBLN1,DCLK1,CDO1,CRLF1,CNR1,SLC25A27,ZNF521,ERC2,TOX,SCRN1,TIAM2,MAGI2,NTM,DLX1,DYNC1I1,EDNRA,TENM1,EPHA5,EYA1,TMEM132C,FOXF2,SYNCRIP,SGIP1,NBEA,DACH2,MEGF10,GABRA4,GABRB1,GLRB,GNG4,GRIA2,GRM3,WIF1,IFI16,KCNA4,NDP,DDR2,CNTN3,PRRX1,ZFHX4,ROBO1,PRR5L,CCDC112,SALL1,CSRNP3,SCN3A,NTNG1,ANKRD6,SLC15A2,LIMCH1,SOX11,NPAS3,TAC1,UNC5D,ADGRL3,TCF4,SATB2,ASXL3,HEY2,KAT6B,TRPS1,RFTN2,RPRM,UGT8,FLRT2,WNT7A,PCDH20,FMN2,KCNAB1,FRMD6" Coexpression Atlas ratio_SC_vs_MESO_2500_K3 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 2.45E-13 1.25E-09 3.25E-12 2.96E-11 206 776 "TTYH1,SYN3,CSMD2,TMEM132B,ADCYAP1R1,UNC5A,NLGN4X,SEMA6A,SYT13,DOC2A,LRFN1,PPFIA2,CNIH2,VAT1L,PPP4R4,CARMIL3,CACNA1A,SYT6,VSTM2A,CLDN10,DCLK1,CHGA,CHRNA4,RAB3C,CHRNB2,NRXN1,FAM19A5,PCYT1B,FAM149A,ANKRD35,IGDCC3,HS3ST5,NECTIN3,CRMP1,C1QL2,LRRC3B,ATRNL1,GALNT9,RIMS4,FAM131B,ECE2,HDAC9,KATNAL2,TOX,PHYHIP,BRINP1,ARMCX4,JAKMIP2,PARD6A,RABGAP1L,CHRDL1,HS3ST2,FAM57B,DPYSL2,ST8SIA3,CACNG7,AASS,LINC00599,ELAVL2,SEZ6,EPHB1,ANKRD13B,ETV1,PIPOX,FABP7,TUBB4A,PPP1R1B,ZNF589,OLFM1,ACTL6B,MAD2L2,HPCAL4,FLT1,SYT3,CSPG5,NSG1,TVP23A,JPH4,SALL3,SRRM4,IGSF5,RUNDC3A,TTBK1,RND1,GLDC,TOX3,PCDH11X,GNG3,GNG4,TDRKH,LPAR4,MCHR1,PCLO,GRIA4,GRM3,LINGO1,WIF1,IGSF21,C1orf94,HRH3,ARHGAP36,C9orf129,LRRC75A,CELF5,ATCAY,BTBD17,SHISAL1,KNDC1,IGSF1,SCIN,LRRTM3,KCND2,KCNN2,KCNN3,KCNQ2,KHK,KIF5A,CAMK2N2,FGFBP3,C2orf80,SCAMP5,WDR49,CPNE9,SCG3,DDX25,FXYD7,NAP1L2,NAP1L3,NEFM,NELL2,NOS1,NOVA2,NPTX2,NTRK3,ZDHHC22,PAH,PAK3,GDAP1L1,CAMKV,PLP1,EPB41L4B,POU3F4,FSD1,PPP2R2B,GDPD2,PTN,PTPRN,PTPRZ1,TMEM145,NKAIN1,ZMAT4,RGS7,RIT2,RORB,RIMKLA,STX1B,RYR1,DRAXIN,PPM1E,BCAN,NLGN1,LRRC55,SEPHS1,SHANK2,IGSF9B,SNCB,TRERF1,SOX2,NMNAT2,LHFPL4,LRRC4,SOX21-AS1,STAC2,NECAB1,RHBDL3,ARHGEF9,ARC,SYP,SYT1,COBL,MTCL1,PJA1,WWC1,WSCD1,ACSL6,TMEM151B,SLC19A3,RNF175,TEX15,CHST8,FBXL16,ENHO,RELL2,TLL2,ANKRD24,KCNE5,VGF,VSNL1,TSPAN11,RBFOX3,TCEAL7,KCNAB1,PAK5,TMEM63C,NETO1,FAM198A" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.45E-13 1.25E-09 3.25E-12 2.96E-11 127 413 "ADD1,ADD3,PNMA8B,PCDH19,TAOK1,ARHGAP20,LCORL,PKP4,DDX3Y,ATP2B1,DOCK11,BACH1,SGCE,IL33,VSTM2A,RUNX1T1,CDH2,ZNF445,SRSF11,CHM,SLIT2,PLAA,COL4A5,RBM39,TENM4,PUM1,FGFR1OP2,TCAF1,AIF1L,ZEB2,ZC3H11A,GSDME,CDON,EDNRA,EIF4G1,EPB41L2,LRRC17,SRRM1,SCML2,MEX3B,ANKFY1,SMC2,APOPT1,SRCAP,CSDC2,PCDH11X,LPAR4,GRIK1,GRM7,WIF1,RASSF8,HAS2,KLF12,KCND3,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,MYBPC1,NASP,NFIA,CNOT4,PCDH9,PDPK1,NALCN,PIK3R1,PLTP,RC3H2,PRRX1,FAT3,SH3KBP1,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,TMLHE,ROBO2,MEG3,NCBP3,ATXN2,FNIP1,SFPQ,TRA2B,ARX,CHD9,WDR37,SLC12A2,SCMH1,TET1,ZKSCAN3,ZCCHC24,SPP1,ZC3H13,RBM26,TROVE2,RGL1,PRRC2C,SYNE2,KLHL4,CLASP1,PCDHB9,OBSL1,CBX5,ASXL3,R3HDM1,TNS1,RBFOX2,TPM1,NR2C2,TRPS1,SSBP2,UBE3A,UBTF,FLRT2,VLDLR,WNT7A,TRIM9,ADAMTS9,SNX27,GAN,SENP7" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.67E-13 1.36E-09 3.53E-12 3.21E-11 131 431 "ABAT,RNF150,PCDH19,OSBPL6,ARHGAP20,SYT13,DPP10,EPB41L5,VAT1L,TNRC6C,ARRB1,ASTN1,NOL4,ADGRB3,NRP2,CA4,CA8,CA12,CALB1,KALRN,VSTM2A,CD38,LGI1,CHGB,CNTN1,NSL1,CRMP1,CRYM,SNCAIP,RIMS2,NTM,CCDC3,GRIN3A,DNM2,DUSP9,ABCC9,EBF1,HEYL,EFNA3,PLXNC1,EPHB1,CDHR1,EYA1,MRVI1,ST3GAL6,RASL10A,DACH2,FYB1,MEGF10,GABRB3,GALC,GAP43,DNER,IGSF5,FREM1,GGTA1P,BRD8,ADGRA3,GRIA1,GRIA4,GRM3,PTPRT,FAM19A2,HAS2,HP,NEGR1,KCNA1,KCNC2,CLEC18A,TM6SF1,MMP16,MN1,NCAM1,NCF2,NPTX1,NTRK2,DDR2,CLDN11,OXTR,CNTN3,PCDH8,PRTG,PDE1C,PRRX1,PTPRB,PTPRO,PTX3,FAM184A,GAL3ST4,DUSP15,ZFHX4,KIRREL1,PRR5L,MEG3,SALL1,CSRNP3,LRFN5,SCN2A,SCN8A,ST8SIA1,ANKRD6,SLC14A1,CXXC4,SORCS3,DDN,CLSTN2,THSD1,NEK4,TMEM150C,SYT4,TAL1,ANO4,SATB2,PCDHB3,TEK,THBS4,HEY1,ASXL3,TLR4,NPL,RGMB,STXBP4,TRPC3,TTPA,TMEFF2,ZNF184,INTS3,LRP8,MRPL47,CERS6,NETO1" Coexpression Atlas ratio_EB_vs_SC_1000_K5 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 2.76E-13 1.41E-09 3.64E-12 3.32E-11 128 418 "PCDH19,SORCS2,PCDH10,LRRC4C,LGR5,ASCL1,TTLL9,TTC9B,MYRF,CDK5R2,CABP7,LGI1,NOG,LHX2,CNR1,CNTFR,HAPLN1,PYGO1,DCC,DCT,LYPD1,CCDC3,DUSP9,EDN3,EDNRA,ELAVL3,ELAVL4,EMX2,ERBB4,NCALD,CLVS1,TMEM132C,ZIC4,ZMYND10,PSD2,NSG2,DACH2,ADGRA1,PHYHIPL,ILDR2,CPLX2,FREM1,PCDH17,GHR,CCDC184,STMN2,GRIA2,C1QL4,GRIK1,GUCY1A1,CELF3,SCRG1,C2orf72,NKD1,HES5,LIX1,SCRT2,INSM1,LRRTM1,NME9,ITIH2,KCNA2,CDH20,CLEC18A,C1orf194,MAP6,LRP1B,TAGLN3,RSPO2,MYT1,NELL1,NHLH1,NTRK2,OLR1,PAX6,PENK,HMGCLL1,PDZRN4,POU3F2,LRRN3,PRPH,RFX4,ZFHX4,ROBO2,RPE65,RTN1,AMER2,LINC00461,SMPD3,SOX6,TRIM67,SLIT1,DMRTC1,SNAP25,ANKFN1,SCN3B,ENKUR,NPAS3,CLSTN2,SST,SYT4,CNTN2,VWA3A,PCDHGB6,TF,DNAH7,ASXL3,RIMBP2,DOK6,TRH,LRRC24,PPIL6,RFTN2,AMOT,FAM181B,ZIC1,CFAP52,EMX2OS,CRB2,STMN4,ADAMTS9,SCG2,SLC17A6,DNAH10,FAM13C,SLC39A12,FAM181A,PRRT4" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_1000 DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.91E-13 1.48E-09 3.83E-12 3.49E-11 212 806 "ABCF1,ACTN2,KDM5D,ARID1A,RNF157,ADD1,PNMA8B,NR0B1,TAOK1,ARHGAP20,SEMA7A,LCORL,PKP4,GAS7,LGR5,ARHGDIG,ASPH,DDX3Y,ATP2B1,RNF182,DOCK11,BACH1,MMD2,BTRC,RUNX1T1,CBLN1,RGN,CDH2,CDH10,ZNF445,SRSF11,CHGB,CHM,SLIT2,PLAA,NMT2,QKI,COL9A1,COL9A3,SLC4A7,RBM39,TENM4,FAM169A,DZIP3,PPP1R16B,PLCXD3,PUM1,DOCK4,FGFR1OP2,GAPVD1,RIPOR2,MATR3,KIAA0586,AIF1L,DCT,ZEB2,ZC3H11A,GSDME,G3BP2,DTNA,DTNB,EDNRA,PHF20L1,APH1A,PLXNC1,EIF4G1,ELAVL2,EMX2,EPB41L2,SRRM1,FAM198B,PTK2B,SCML2,ATP8A1,CHST15,PRMT5,MEX3B,SEMA6C,ANKFY1,SMC2,APOPT1,FYN,GABRA4,MTHFD2,GATM,TUBGCP4,SRCAP,CSDC2,PPARGC1A,TNRC6A,ZNF638,LPAR4,GPR37,DIDO1,KIF3A,FAM19A2,KAT7,GUCY1A1,MAEL,TOX2,INSM1,KCND2,KCNH1,MAP4,CHIC1,MEF2C,MEIS1,MEIS2,KITLG,MID1,MMP16,SAMD5,MSI1,MTR,MYCN,MYH6,NEXMIF,NASP,NEFM,NFIA,NODAL,CNOT4,OCRL,PAK3,PCDH9,PCSK5,PDPK1,OLA1,SERPINI1,JAKMIP1,PLEC,PLTP,RC3H2,SH3KBP1,LRRN3,PPP2R5E,KANSL1,MAPK8,DIRAS2,ANKHD1,PTPRE,TMEM255A,SH3TC2,C1orf54,PBRM1,RNASEL,TMLHE,ROBO2,MEG3,ATXN2,FNIP1,SOX6,SFPQ,TRA2B,ARX,CHD9,SYBU,WDR37,PKNOX2,SLC12A2,SCMH1,EFHD1,TET1,CPEB4,ZKSCAN3,SMARCA4,SNRPN,SOX2,SOX5,ZCCHC24,SP4,ZC3H13,KIF1B,RBM26,TROVE2,LARP4,RGL1,ADHFE1,SULF2,PRRC2C,SYNE2,TACC1,KLHL4,TCF7L2,CLASP1,OBSL1,AHCYL2,LEFTY2,HHIP,HEY1,CBX5,ACTR6,ASXL3,R3HDM1,TNS1,TPM1,NR2C2,SSBP2,UBTF,FLRT2,TBC1D15,ZIC3,ZNF23,STOX2,ADAMTS9,NAV2,SNX27,FIP1L1,RSPRY1,ST8SIA2,GAN,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.06E-13 1.56E-09 4.02E-12 3.66E-11 27 39 "SYT13,ANK3,RUNX1T1,INA,ELAVL3,TMEM35A,RCAN2,NSG2,NSG1,GAP43,STMN2,CELF3,CELF5,BEX5,TMOD2,RTN1,SCN2A,NAPB,SNAP25,SCN3B,KIF21B,PEG10,SEPT3,SYT4,VGF,CELF4,SCG2" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.32E-13 1.69E-09 4.34E-12 3.96E-11 133 441 "ABAT,GRAMD1B,ADORA1,HECW2,NR0B1,BCAR3,KCNT1,AMH,SEMA7A,GAS7,SHTN1,LGR5,CDC14B,PPP4R4,ARHGDIG,CADPS,MARK4,ATP1A1,ATP2B3,ALDH7A1,BCHE,RGS11,DST,ST3GAL5,SYNJ2,RGN,CDO1,CACNA2D2,ADGRG1,CLU,CLTB,FADS2,COL9A3,MAGED1,VCAN,CST3,PPP1R16B,SCRN1,DCT,JAKMIP2,ELMO1,PLPPR4,SRGAP3,RCAN1,DTNA,DTNB,SIDT2,MRO,PLXNC1,SORBS3,CERCAM,MTSS1L,EPS8,ERBB2,ERBB4,REEP2,FAM198B,PTK2B,TUBB3,ATP8A1,FGF13,SEMA6C,AFF2,CAMKK2,CSPG5,BRPF3,IQGAP2,GATM,PPARGC1A,ADGRA3,GPM6B,GPR37,PADI2,KCNH1,KLHL23,KCNK2,NCOA7,MAN2A2,MATN2,KITLG,MOV10,MSI1,NRBP2,CTNNA3,MYO7A,FXYD6,NELL1,PAK3,PDE2A,PGAM2,SERPINE2,SCHIP1,RASGEF1B,PRKCB,MASP1,PTCH1,PTPRE,SH3TC2,DUSP15,ROBO1,TMEM206,GLDN,RPS6KA2,MRAS,KIF21A,SH3GL2,DOCK10,ST6GAL1,ST8SIA1,SLC6A8,EFHD1,TNIK,UHRF1BP1L,SPP1,TSPYL2,SMOC1,ST5,ADHFE1,TACC1,SIN3B,OBSL1,ZFPM2,THRA,TIAM1,BEX4,TPD52,TRPC3,FNDC5,TST,SGK3,SLC38A1,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.49E-13 1.78E-09 4.55E-12 4.15E-11 122 393 "EMILIN3,ADRB2,FAM135A,TMEM263,CADPS,ATP2B1,MYOM1,CA8,CACNA2D1,CANX,CFL2,RAB3C,KIAA1549L,CNTN1,COL9A1,CNRIP1,VCAN,PLCXD3,ZEB2,RABGAP1L,EDNRB,EIF5,RGS17,DCTN4,EPB41L2,EPHA5,NCALD,ETV1,RASL12,MRVI1,DLC1,KIAA1109,SUCO,CAP2,SYNCRIP,SORBS1,SMC2,PDLIM5,DACH2,PNMA2,DKK3,MEGF10,GALC,RAPGEF6,GFRA2,PCDH17,FERMT2,PRUNE2,GPM6B,HAS2,ZHX1,NEGR1,RBPJ,KCND3,KCNK2,KCNMA1,LAMA2,LIMS1,HECTD2,NCOA7,MBNL1,IL17D,CHIC1,MEIS1,MKLN1,MMP16,NFIA,NPTX2,NTRK2,CLDN11,CNTN3,PCDH9,ENPP2,NALCN,PIK3C2A,SCHIP1,PRRX1,KANSL1,DIRAS2,PTX3,REV3L,LGI2,KCNIP3,RYR3,ATXN1,SCN3A,SH3BGR,SH3GL2,SH3GL3,SCMH1,SORCS3,RIMS1,FAM126B,TNIK,ZHX3,KIF1B,NPAS3,SMOC1,EPB41L3,VPS13A,SYT1,CAMSAP2,AGTPBP1,VWC2,WASHC4,SYNE1,ZFPM2,HHIP,ZFP91,ERCC6L2,R3HDM1,RBFOX2,RASD2,TPM2,RGMB,SYNPO2,TRPC3,TRPS1,SSBP2,VLDLR,RBFOX3,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k4 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.50E-13 1.79E-09 4.56E-12 4.15E-11 74 195 "ADCY2,KLHL13,OSBPL6,ALCAM,ARHGAP20,PCDH10,CADPS,ATP2B1,ADGRB2,IL33,CACNA1D,CACNA2D1,LDB2,CD86,NRXN3,LY86,CNTN1,CNRIP1,AKAP12,ATRNL1,ZEB2,NTM,PLXNC1,EPB41L2,NCALD,MRVI1,HSPA12B,DACH2,DKK3,GABRA1,GAP43,FREM1,RAB40B,GRIA1,GRIA4,GRM7,GUCY1A1,UBE2QL1,ZHX1,NEGR1,IL11RA,KCND3,LAMA2,MATN2,MMP16,CCDC80,MSR1,NDP,CLDN11,PCDH9,PDE3A,GPR85,PENK,TRHDE,PRRX1,NKAIN4,PTX3,LGI2,SYNDIG1,LRFN5,SCN7A,ST8SIA1,CXXC4,SAMSN1,PDLIM2,ANO4,VWC2,SYNPO2,TMEFF2,FLRT2,PROCA1,SPIRE1,NAV3,MSRB3" Coexpression Atlas ratio_SC_vs_DE_500_K5 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 4.17E-13 2.13E-09 5.41E-12 4.93E-11 91 263 "TTYH1,SYN3,UNC5A,VAT1L,SYT6,VSTM2A,CHGA,CHRNA4,CHRNB2,NRXN2,CLU,SLC24A2,ANKRD35,HS3ST5,C1QL2,RIMS4,SEC14L5,RIPOR2,TOX,PHYHIP,JAKMIP2,PARD6A,NTM,ATL1,CACNG7,AASS,LINC00599,SEZ6,ANKRD13B,PIPOX,CEND1,OLFM1,ACTL6B,HPCAL4,JPH4,IGSF5,TTBK1,RND1,GRIA4,GRIN1,SOX21,LINGO1,WIF1,NXPH2,HRH3,LRRC75A,BTBD17,RIPPLY2,LRRTM3,KCNN2,KCNN3,KIF5A,FGFBP3,CPNE9,FXYD7,VWA2,NPTX2,NTRK3,ZDHHC22,PAH,NLGN3,CAMKV,PLP1,PCDH18,EPB41L4B,POU3F4,RAB39A,GDPD2,TMEM145,RYR1,IL17RB,SCG5,SLITRK3,BCAN,LRRC55,TRERF1,KIF21B,SOX21-AS1,SEPT3,RHBDL3,ARHGEF9,ARC,SYP,TAC3,TACR1,ACSL6,TMEM151B,TLL2,TTPA,VSNL1,TSPAN11" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500 FaceBase_RNAseq 4.26E-13 2.17E-09 5.51E-12 5.03E-11 145 496 "SLITRK1,AXIN2,PLEKHH1,EPB41L5,TTLL9,FGF17,NRP2,ZNF599,PROM1,CA4,CA12,HAP1,MAP7,CBLN1,INA,TBRG4,ADGRG1,NRXN2,FAM19A5,CNTFR,IGDCC3,NCAN,FAM169A,CTH,GREB1,CTNND2,RIMS2,JAKMIP2,KBTBD11,CHRDL1,ST8SIA3,PLXNC1,LPAR6,ELAVL2,PLEKHA1,LRRC23,EPHB1,PIPOX,RRAGB,ADGRV1,REEP2,FABP7,ACSL4,TUBB4A,SPSB4,FHL1,NOP56,ZCCHC17,FUT9,PHYHIPL,GABRB3,ILDR2,AHCYL1,TCERG1,GLDC,TOX3,MAP7D2,GPR19,LPAR4,CECR2,STMN2,GRIK3,RNF165,SOX21,CELF3,TOX2,FRMD5,USP51,HSP90AA1,NKD1,ZIC5,HES5,CDH20,KIT,IPO5,KTN1,AQP11,SCG3,MYCN,NAP1L1,NASP,NNAT,NOVA1,NRCAM,ODF2,PRTG,FAM98B,SEMA5B,PKM,PLTP,MAGEL2,POLR2F,POU3F4,IRX1,MAPK10,PROX1,GDPD2,ELOVL2,PTPN13,EML5,CCDC40,FIGN,RFX4,RPL15,RTN1,SALL1,TNFRSF19,HSPA4L,SCG5,KIF21A,NUBPL,PKNOX2,SNRPN,SOX2,NMNAT2,BEX1,PBLD,NEK4,AJAP1,ANKRD28,MTCL1,WWC1,WSCD1,ACSL6,WASHC4,TMEM121,BEX4,PRMT8,CA14,HSPBP1,CADM1,SLAIN1,FLRT1,FAM181B,MGAT5B,RBFOX3,ZIC1,ZIC2,ZIC3,KCNT2,ZBTB16,DPYSL5,NAV2,FZD3,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K5 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 4.73E-13 2.41E-09 6.11E-12 5.57E-11 45 92 "ABR,SHTN1,ASCL1,ATP1A3,HAP1,ADGRG1,SRSF11,NRXN3,ST18,DTNA,ELAVL3,OLIG2,ADGRV1,TUBB3,FOXG1,GAD1,GAD2,SRRM4,RUNDC3A,GPM6A,GRIK2,RNF165,MFSD2A,FAM222A,CELF3,TOX2,FRMD5,HES5,MBP,SHC3,MYT1,NNAT,GDAP1L1,PLXNB1,MAPK10,RTN1,LINC00461,SCG5,MAST1,SNAP25,SYP,MCF2L,UCHL1,DPYSL5,STMN4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.88E-13 2.49E-09 6.28E-12 5.73E-11 117 373 "PNMA8B,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,LTBP4,GPAM,APOC1,LRRC4C,LGR5,PPP4R4,PDE8B,TMEM108,SLC4A4,MYRF,CACNB2,CALB1,RUNX1T1,REPS2,DCLK1,MAGI1,CLU,CNTFR,AKAP5,ZNF521,CLIP3,ATRNL1,PLXNA4,BOC,DOCK4,DAPK1,DCT,MAGI2,SRGAP3,DNM1,DRP2,EDNRA,EGFR,PLXNC1,EMX2,LRRC17,MTSS1L,NRN1,FAM198B,FABP7,FLNC,AFF2,ST6GALNAC3,NSG1,GABRA4,GABRB1,GATM,GFRA2,FREM1,GLI2,PCDH11X,GUCY1A1,TCEAL6,SHISA6,IGF1,NKD1,PLD5,KCND2,KLHL23,MAP2,MATN2,MEIS1,KITLG,MOV10,MTR,LAYN,NEXMIF,NFIA,NME4,NPR2,PCDH9,PDE1A,PDGFRA,SERPINI1,PIK3R1,PLP1,PCDH18,PRRX1,LAMA1,GDPD2,PTN,TMEM255A,ROBO2,TMEM206,LGR4,MEG3,KCNIP1,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,SLC4A3,PKNOX2,PALLD,KDM3A,PEG10,NPAS3,SMOC1,ST5,SULF2,ADGRL3,TEX15,ZFPM2,ACTR6,DAAM2,TNNT1,FNDC5,VSNL1,LYPD6,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.55E-13 2.83E-09 7.13E-12 6.49E-11 121 391 "AXIN2,USP31,PCDH10,SYT13,APC,TNRC6C,MIER1,CADPS,INSYN2B,RNF182,NRP2,DST,CH25H,RUNX1T1,CBLN1,RGN,MYOM2,DCLK1,CDO1,CRLF1,FOXN3,CNR1,SLC25A27,ZNF521,VCAN,ERC2,TOX,SCRN1,ZEB2,TIAM2,MAGI2,NTM,DLX1,DNM1,DYNC1I1,EDNRA,TENM1,EPHA5,EYA1,TMEM132C,FOXF2,SYNCRIP,SGIP1,NBEA,DACH2,DKK3,MEGF10,GABRA4,CHL1,GABRB1,ILDR2,GFRA2,GLRB,GNG4,GRIA2,GRM3,WIF1,RASSF8,BACH2,IFI16,IGFBP1,KCNA4,KIF5C,ASPRV1,MEIS2,MYH3,NDP,NFIA,DDR2,PAH,CNTN3,PRRX1,KANSL1,PTPRG,PTPRO,PTPRZ1,ZFHX4,ROBO1,ROBO2,PRR5L,CCDC112,SALL1,CSRNP3,SCN3A,NTNG1,ANKRD6,SLC15A2,LIMCH1,RIMS1,SOX2,SOX11,ZHX3,NPAS3,CLASP2,EPB41L3,TAC1,UNC5D,ADGRL3,TCF4,SATB2,PCDHB7,ASXL3,ZFP91,ERCC6L2,HEY2,KAT6B,RBFOX2,SYNPO2,TRPS1,RFTN2,RPRM,UGT8,FLRT2,WNT7A,PCDH20,FMN2,KCNAB1,FAM13C,NUP214,MSRB3,FRMD6" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 6.55E-13 3.34E-09 8.39E-12 7.65E-11 144 494 "ACTN2,SLITRK1,APOC1,APOC2,SPTBN4,ZFYVE28,PDE8B,ASTN1,ATP1A3,ATP2B2,DOCK11,BARD1,ZNF599,JAZF1,GPC2,IL33,HAP1,MAP7,CBLN1,LRBA,KCNAB3,CCPG1,ADGRG1,VAX2,IQCK,IGDCC3,CRYBB1,CLIP3,CRYM,SNCAIP,PLCH2,ST18,FGFR1OP2,KATNAL2,TOX,JAKMIP2,C8orf34,GSDME,FAM107B,DLX1,DUSP9,MAMLD1,ABCC9,ELAVL4,SLC43A2,CEP85L,ETV1,EYA1,TMEM132C,PTK2B,HPCAL4,FOXG1,ZMYND15,AFF2,SYT3,SMC2,STAU2,TMEM151A,ABLIM2,ARPP21,HIGD1B,SRRM4,KIAA1841,ZNF276,PCDH11X,CECR2,GRK4,PCLO,GRIK2,MFSD2A,GUCY1A2,HLF,HPSE2,IGFBPL1,ICA1,IGF1,KNDC1,SCIN,LIX1,INSM1,ZNF385B,KCNJ5,GPR155,MAN2A2,MAP2,SHC3,CPNE9,ADAM22,BCO1,RSPO2,MYT1,TCEAL5,NFE2L2,NPY,CLEC9A,NRGN,ODF2,GPR137C,PAX6,PDE4D,PRRX1,DIRAS2,CNTLN,ELOVL2,STRC,RAP1GAP,NWD1,ENOX1,FEZF2,DUSP15,REV3L,RFX4,ZFHX4,MYH14,PLPPR3,DGLUCY,LINC00461,SCG5,SLC1A2,PREX2,DHX30,TET1,SMARCC2,BDP1,ARHGAP26,LMO3,ROBO3,SATB2,SYNE1,PHF24,LEFTY2,NR2E1,TMOD1,AMACR,STXBP4,TRPS1,UCHL1,ZNF23,PMEPA1,STMN4,TMEM163,DNAH10,CERS6,SENP7" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.09E-13 3.62E-09 9.07E-12 8.26E-11 111 349 "NCKAP5,RNF157,SLC12A5,SORCS1,RNF150,HECW2,FAM135A,ASPH,RNF182,BACH1,BMPR1B,LDLRAD4,FOXK1,RUNX1T1,CDC27,CDH2,CDH10,CDO1,RCBTB2,SLIT2,NRXN3,HAPLN1,ANKRD44,NCOR1,APPL1,HDAC9,BRINP1,ZEB2,CEP170,EDIL3,EDNRB,SEMA3D,RBM12,TENM1,ELAVL4,ETV1,TMEM132C,SCML2,UBE2E3,MEX3B,FOXF2,SLC37A3,DACH2,MEGF10,GABRA4,GABRB1,GABRB3,DNER,GLRB,RAB40B,EML4,RAPGEF4,GUCY1B1,MAP4K5,KLF12,AGFG1,IFI16,ITGAV,KCNK2,MEF2C,RSPO2,NAP1L2,NAP1L3,NDP,DDR2,CNTN3,PCDH8,GPR85,NLGN3,PCDH18,SLC36A4,GRAMD1C,PTCH1,ZIK1,FAT4,ARID4A,TSPY26P,RGS4,SEC61A2,NUDT11,ZFHX4,ARMH4,HUNK,CCDC112,FNIP1,ITSN1,DOCK10,DZIP1,WDR37,CMTR2,PDZRN3,SON,NPAS3,THSD1,ELOVL4,NEK4,DIP2A,PLCB1,MTCL1,ADGRL3,PCDHB3,HIF3A,TRPS1,SSBP2,ZNF711,MKRN3,CELF4,REEP1,GOPC,FXR1,SOCS4" Coexpression Atlas ratio_SC_vs_MESO_500_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 7.69E-13 3.92E-09 9.81E-12 8.94E-11 34 59 "TTYH1,NRXN2,GALNT9,NTM,AK5,EDIL3,ATL1,TMEM35A,LRRC17,CEND1,ACTL6B,HPCAL4,TMEM151A,GAP43,DNER,CCDC184,WIF1,SHISAL1,KCNMA1,MAP2,NEFM,PAK3,PCDH18,KLK6,PTPRN,PTPRO,LRRC55,SOX1,SOX3,LMO3,CNTN2,TMEFF2,CRB2,DPYSL5" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.72E-13 3.94E-09 9.82E-12 8.95E-11 113 358 "ABAT,FMNL2,ADCY2,AXIN2,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,GPAM,APOC1,LRRC4C,LGR5,ATP2B3,BCHE,CACNA1G,CACNA1D,CACNB2,CALB1,SLIT2,ATRNL1,VCAN,PLXNA4,BOC,DOCK4,DAPK1,MAGI2,SRGAP3,DNM1,DRP2,EDNRA,EGFR,MRO,PLXNC1,EMX2,LRRC17,NRN1,FLNC,AFF2,NSG1,GABRA4,GABRB1,GATM,GFRA2,FREM1,PCDH11X,GPM6B,GUCY1A1,GUCY1B1,TCEAL6,IGF1,NKD1,PLD5,KCND2,KLHL23,SYTL4,MATN2,MEIS1,KITLG,CCDC80,MTR,LAYN,MYO9A,NEXMIF,NCAM1,NELL1,NFIA,NPR2,PCDH9,PDE1A,PDGFRA,ENPP2,CDK14,PIK3R1,FXYD1,PCDH18,PRRX1,LAMA1,GDPD2,PTN,TMEM255A,FAT4,RNASEL,ZFHX4,TMEM206,LGR4,MEG3,SEMA6D,TNFRSF19,SLC4A3,SCMH1,PALLD,KDM3A,UHRF1BP1L,NPAS3,SMOC1,ST5,ADAMTS17,ADGRL3,TCF12,PSD3,TEX15,ZFPM2,ACTR6,DAAM2,TNNT1,FNDC5,DCBLD1,TST,FLRT2,VSNL1,LYPD6,WNK3" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.87E-13 4.02E-09 9.99E-12 9.10E-11 210 804 "ABAT,METAP1D,FMNL2,ADD3,AXIN2,MTA3,KLHL13,NR0B1,CC2D2A,ARHGAP20,KCNT1,AMPH,OGT,LRCH2,SEMA7A,MAP4K3,USP28,APOC1,CACHD1,SHTN1,LGR5,CDC14B,CDK10,SEMA4G,PPP4R4,PDE8B,CAPRIN2,INSYN2B,ATP2B3,RNF182,BCHE,RGS11,DST,WASF1,CACNA1D,CACNB2,CALB1,RGN,SLC16A4,REPS2,CDH2,DCLK1,MAGI1,ADGRG1,CHRM4,CLU,NMT2,FADS2,AKAP7,AKAP5,FEZ1,PLXNA4,CTH,GREB1,BOC,DOCK4,GPRASP1,DAPK1,MAGI2,FBXO25,SACS,SRGAP3,DOCK2,SLC12A6,DRP2,TSPAN5,RASGRP1,KLHL5,OPTN,EGFR,MRO,PLXNC1,CERCAM,TMEM35A,EMX2,EPB41L1,NRN1,FGF11,PRKAG2,PCYOX1,AFF2,KHDRBS3,NSG1,ZMAT1,GABRA4,GABRB1,TRAF3IP2,GALC,GATM,NEU3,SESN1,MALT1,PCDH11X,ADGRA3,GRIK3,RASSF8,PACSIN2,TCEAL6,SHISA6,NKD1,PLD5,IL6ST,DIPK1A,SLC35G1,KCND2,KLHL23,TTYH2,SYTL4,ARHGAP12,GPR155,MAOB,MAP2,KITLG,MOV10,SESN3,CCDC80,MTR,LAYN,MYO9A,NEXMIF,NFIA,NNAT,NPR2,NUCB2,OPHN1,ETFRF1,PDE1A,ENPP2,CDK14,SERPINI1,SEMA5B,PCDH18,PPARA,PPP2R5C,PPP3CC,RASGEF1B,MAPK9,GDPD1,CNNM2,VPS13C,LAMA1,GDPD2,CNTLN,C1orf54,FAT4,REV3L,RNASEL,ZFHX4,TMEM206,LGR4,PTGR2,MEG3,HUNK,SEMA6D,SCN2A,PRCD,TNFRSF19,STUM,RASA3,SH3BGR,FRMPD1,CNKSR2,ST8SIA1,ABLIM3,SLC4A3,SCMH1,PDZD2,TNIK,KDM3A,ZHX3,UHRF1BP1L,PEG10,ARHGAP26,TSPYL2,NPAS3,LHPP,SMOC1,ST5,FGD4,ADAMTS17,FNDC9,SLC37A2,ADGRL3,RPGRIP1L,TCF12,DOCK9,OBSL1,TEX15,DNAH7,GZF1,ACTR6,DAAM2,TNNT1,FNDC5,DCBLD1,TST,UBE2H,UCHL1,VAV2,VSNL1,ZNF23,ELFN1,LYPD6,REEP1,TMEM178A,NAV2,WNK3,SNX14,FRMD6,DPF3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg3_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.35E-13 4.26E-09 1.05E-11 9.61E-11 38 71 "SYT13,ANK3,SEPT7,CHGA,PNPLA8,CTNND2,ELMO1,NYAP1,ELAVL3,OLFM1,NSG2,NSG1,PNMA2,GABRB3,GAP43,GPM6A,STMN2,CELF3,MAP6,MARK1,BEX5,NCAM1,PCSK1,SNX10,RTN1,SCN3A,SNAP25,SCN3B,MYCBP2,PEG10,CLASP2,SYT4,ASXL3,VGF,CELF4,REEP1,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Subtype_iDAc_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 8.35E-13 4.26E-09 1.05E-11 9.61E-11 38 71 "TMEM132B,TMCC3,PCDH10,SYT13,ANK3,CALB1,INA,CHGB,ELAVL3,TMEM35A,NSG2,NSG1,FUT9,GAP43,GFRA1,C1QL1,TOX3,GNAO1,GPM6B,STMN2,CELF3,NEGR1,HTR2A,LSAMP,CD200,NCAM1,PBX1,PLEKHB2,RET,RTN1,SCN2A,SCN3B,PEG10,SSTR2,SEPT3,VGF,CELF4,SCG2" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000 DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.11E-12 5.64E-09 1.39E-11 1.27E-10 208 797 "TKTL1,ADD1,ADD3,PNMA8B,ADORA1,INTS2,NR0B1,TAOK1,SEMA7A,LCORL,PKP4,LGR5,PDE8B,ASPA,CAPRIN2,DDX3Y,INSYN2B,RNF182,DOCK11,BACH1,RGS11,SYNJ1,ST3GAL5,ARHGEF7,SGCE,BTRC,CACNB2,CALB1,LONRF2,ZNF445,SRSF11,CHM,SLIT2,KMT2C,CLU,NMT2,CNR1,COL4A5,RBM39,TENM4,DZIP3,GREB1,PUM1,DOCK4,FGFR1OP2,GAPVD1,TCAF1,KIAA0586,AIF1L,MAGI2,ZC3H11A,GSDME,SNAP91,SACS,G3BP2,RABGAP1L,DYNC1I1,CDON,DOCK2,DRP2,DTNB,DNAJB6,EDNRA,RASGRP1,PLXNC1,EIF4G1,ELAVL2,CALCRL,EMX2,EPB41L2,SRRM1,NRN1,SCML2,ATP8A1,KIAA1109,MEX3B,ANKFY1,SMC2,APOPT1,ATP6V1H,STAU2,ZMAT1,GABRA4,GABRB1,ILDR2,GATM,SRCAP,CSDC2,GGT5,MAP7D2,TDRKH,LPAR4,GPR37,GRK4,DIDO1,KIF3A,GUCY1A1,MAEL,MIER3,SHISA6,KCND2,TTYH2,SYTL4,MAP4,CHIC1,MEIS1,KITLG,MMP16,SAMD5,MSI1,MYO5A,MYO9A,NEXMIF,NASP,NFIA,CNOT4,OCRL,GLIPR1L2,PCDH9,PDPK1,OLA1,ABCB1,SERPINI1,SEMA5B,TMIE,PIK3R1,JAKMIP1,PLEC,PLP1,RC3H2,KANSL1,MAPK8,EML5,C1orf54,SEC61A2,RNASEL,TMLHE,ATP8B4,MEG3,RYR1,NCBP3,SEMA6D,SATB1,ATXN2,LRRTM4,PRCD,FNIP1,TNFRSF19,SFPQ,TRA2B,ARX,CPEB3,CHD9,SYBU,SLC12A2,NAPB,SCMH1,CPEB4,ZKSCAN3,SMARCA4,SNCA,MYT1L,TNIK,SOX5,ZC3H13,ARHGAP26,RBM26,LARP4,PRRC2C,SYNE2,SYN2,SLC37A2,ANKRD12,CAMTA1,DMXL2,CLASP1,OBSL1,AHCYL2,CCDC173,TEX15,DNAH7,CBX5,ACTR6,DAAM2,R3HDM1,NR2C2,FNDC5,TSC1,SSBP2,UBE3A,UBTF,UGT8,FLRT2,VSNL1,ZNF711,ZNF23,EMX2OS,REEP1,ADAMTS9,TMEM178A,NAV2,SNX27,PHTF2,RSPRY1,RNF170,KLHDC1,GAN,SENP7" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.11E-12 5.67E-09 1.40E-11 1.27E-10 214 826 "EMILIN3,NCKAP5,RNF157,SLC12A5,SORCS1,USP31,RNF150,ADRB2,HECW2,TAOK1,ALCAM,FAM135A,AMPD3,APAF1,PHYHD1,SFMBT2,TMEM263,ASPH,DDX3Y,RNF182,MYOM1,ADAM23,BACH1,BARD1,BCHE,NRP2,BMPR1B,NIPA1,LDLRAD4,FOXK1,CACNA2D1,CAMK2D,VSTM2A,RUNX1T1,CDC27,CDH2,CDH10,CDO1,RCBTB2,SRSF11,SOCS6,SLIT2,NRXN3,AKAP5,ABI3BP,CRHBP,AKAP12,HAPLN1,ANKRD44,NCOR1,VCAN,APPL1,HDAC9,BRINP1,ZEB2,MYEF2,MFAP3L,CEP170,SV2B,AK5,EDIL3,EDNRB,SEMA3D,TMTC1,RBM12,TENM1,ELAVL4,EML1,EPHB1,EPS8,ETV1,MRVI1,TMEM132C,SCML2,DLC1,UBE2E3,MEX3B,CAP2,FOXF2,SLC37A3,PDLIM5,DACH2,PNMA2,ZMAT1,DKK3,MEGF10,GABRA4,CHL1,GABRB1,GABRB3,DNER,ARFIP1,PCDH17,GHR,LYVE1,GLRB,PCDH11X,RAB40B,GPM6B,EML4,RAPGEF4,GUCY1B1,MAP4K5,RASSF8,KLF12,HNMT,ZDHHC15,AGFG1,IFI16,RBPJ,ITGAV,KCND3,KCNK2,KIT,MAOB,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,RSPO2,MYO6,NAP1L2,NAP1L3,NCAM1,NDP,ALDH1L2,NPTX2,HCN1,DDR2,CNTN3,PCDH8,PDE4B,PDE4D,GPR85,NLGN3,ANLN,PCDH18,SLC36A4,PRKCB,GRAMD1C,PTCH1,ZIK1,PTPRB,FAT4,ARID4A,TSPY26P,RGS4,TTLL7,SEC61A2,NUDT11,ZFHX4,SETD5,ARMH4,HUNK,CCDC112,SCN7A,FNIP1,ASRGL1,ITSN1,SH3GL3,DOCK10,ST8SIA1,DZIP1,WDR37,SLC14A1,SPHKAP,CMTR2,PDZRN3,SON,SOX2,SOX5,ZHX3,PEG10,NPAS3,C11orf87,THSD1,ELOVL4,NEK4,DIP2A,PRRC2C,PLCB1,COBL,MTCL1,ADGRL3,AGTPBP1,PCDHB3,HIF3A,TEK,ZFPM2,HHIP,TLR4,ERCC6L2,TNNT1,RBFOX2,RGMB,SYNPO2,TRPS1,SSBP2,UBE3A,WRN,ZNF711,AGMO,MKRN3,CELF4,REEP1,GOPC,FAM13C,ACTR3B,MSRB3,FXR1,NETO1,SOCS4,SPATA13" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000 DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.26E-12 6.42E-09 1.58E-11 1.44E-10 208 798 "NDRG2,ADCY5,ADCY8,ADD1,ADD3,PNMA8B,WDR35,TAOK1,C1QTNF3,SPARCL1,SRPX,ARHGAP20,LTBP4,LCORL,PKP4,PTCH2,DDX3Y,ATP1A2,ATP2B1,MYOM1,BACH1,BMPR1B,JAZF1,IL33,BTRC,CACNB2,VSTM2A,RUNX1T1,RGN,DCLK1,ZNF445,SRSF11,CHM,SLIT2,PLAA,CLU,NMT2,COL4A5,ABI3BP,CP,FAM171B,RBM39,CSF1R,FEZ1,PLCXD3,PUM1,FGFR1OP2,GAPVD1,RIPOR2,MATR3,AIF1L,ZEB2,MFAP3L,ZC3H11A,GSDME,G3BP2,CHRDL1,CALN1,CDON,EBF1,EDN3,EDNRA,EDNRB,APH1A,EIF4G1,ING4,ELN,CALCRL,EMX2,EPB41L2,LRRC17,SRRM1,ETV1,TMEM132C,SCML2,EFEMP1,FCGRT,KIAA1109,FGF1,FGF12,FHL1,SEMA6C,ANKFY1,SMC2,APOPT1,UFM1,GABRA4,GABRB1,ILDR2,GAD1,DNER,SRCAP,CSDC2,LYVE1,TNRC6A,GLUL,CNDP1,LPAR4,PARD3B,NR3C1,GRM7,GSN,KIF3A,RASSF8,HAS2,KLF12,MIER3,HLF,IGFBP1,JAK1,KCNC2,KCND3,KCNK1,LAMA2,VWA5A,GPR155,MAOB,MAP4,MATN2,CHIC1,MEF2C,MEIS1,MEIS2,MMP16,SAMD5,NRBP2,MYH3,MYO6,NASP,NDP,NFIA,NFIX,VWA2,NPY,OCRL,CLDN11,PCDH9,PCSK5,PDGFRA,GPR85,PENK,NALCN,PIK3R1,PLEC,FXYD1,PLTP,RC3H2,PRRX1,FAT3,SH3KBP1,KANSL1,MAPK8,C1orf54,SUSD4,VEPH1,RNASEL,LGI2,TMLHE,MRAP2,MEG3,ATXN1,ATXN2,FNIP1,SFPQ,TRA2B,ARX,CHD9,SLC12A2,SLC15A2,TET1,ZCCHC24,SP4,ZC3H13,TROVE2,CLSTN2,PRRC2C,SYNE2,TACC1,TRIM2,WASHC4,PCDHB9,OBSL1,AHCYL2,HHIP,CBX5,R3HDM1,TNNT1,TNS1,RASD2,TPM1,NPL,NR2C2,TRPS1,SSBP2,RPRM,UBE3A,UBTF,FLRT2,VLDLR,PMEPA1,ADAMTS9,NAV2,SNX27,RGS7BP,RNF170,SSPN,GAN,SENP7" Coexpression Atlas PCBC_EB_blastocyst_500 Progenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 1.29E-12 6.57E-09 1.61E-11 1.47E-10 144 498 "AGT,APOC2,ASCL1,CACNA1G,MYRF,CDH18,LGI1,LHX2,FAM19A5,IGLON5,COL9A1,IGDCC3,ATRNL1,PHACTR3,CNTNAP2,DCT,DNAH9,DPP6,DUSP9,USH1C,EDN3,ELAVL3,ELAVL4,EMX2,ADGRV1,NRN1,FABP7,TMEM132C,ZIC4,FOXF2,NSG2,DACH2,B3GAT1,TMEM151A,PHYHIPL,GABRA2,CHL1,ILDR2,CPLX2,GFRA2,FREM1,GJB1,PCSK1N,GPM6A,CCDC184,STMN2,GRIA2,C1QL4,GRIA4,GRM8,GUCY1A1,CELF3,WIF1,UBE2QL1,NXPH2,SCRG1,IGFBPL1,HP,SHISA6,CELF5,BTBD17,C2orf72,IGF1,NKD1,LIX1,INSM1,ITIH2,KCNQ2,LRRC4B,CLEC18A,C1orf194,MAPT,SCG3,MTTP,RSPO2,MYL3,NCAM1,NEFM,NELL1,NELL2,NHLH1,NNAT,NTRK2,OLR1,PAH,KCNK10,PAX6,PCDH8,PDGFRA,PENK,GDAP1L1,HMGCLL1,PDZRN4,PRRX1,NECAB2,MAGEL2,POU3F2,POU3F4,NKAIN4,PRPH,RELN,LAMA1,PTH1R,PTPRD,PTPRO,TMEM255A,RFX4,HUNK,KCNIP1,RXRG,LINC00461,TMEM200C,SLC1A6,LRRC55,SLC8A3,TMEM132D,SLIT1,SNAP25,CABCOCO1,SOX1,SOX3,SOX10,ENKUR,CLSTN2,SST,SYT4,TAC1,TAC3,CNTN2,TF,ASXL3,RIMBP2,FLRT1,FAM181B,ZIC1,ZIC3,KCNT2,CRB2,MKRN3,DPYSL5,STMN4,SCG2,CBLN2,FAM181A" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkC_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.50E-12 7.62E-09 1.86E-11 1.70E-10 34 60 "ASIC1,ASCL1,INA,SEPT7,NRXN2,NIPBL,ELAVL4,EN2,FABP7,TAOK3,C1orf61,SGIP1,NSG2,ZMAT1,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,TOX2,HSP90AA1,HES5,NCAM1,NFIX,NOVA1,SLC25A23,RTN1,SCN2A,SCN3A,MYT1L,SIN3B,CELF4,PAK5" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb_Subtype_iNb1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.54E-12 7.86E-09 1.92E-11 1.75E-10 37 69 "SYT13,ANK2,ANK3,CACNA1B,DLGAP2,CHGB,TMEM130,SEZ6L2,ELAVL3,TMEM35A,RCAN2,EPHA5,NSG2,NSG1,GAP43,GNG4,STMN2,CELF5,MGAT3,SAMD14,BEX5,PCSK1,PPP2R2B,PTPRN,RTN1,SCN2A,SNAP25,SCN3B,LMO3,SYT4,TAC1,DNAJC12,VGF,CELF4,SCG2,SLC17A6,NETO1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb3_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 1.55E-12 7.91E-09 1.92E-11 1.75E-10 35 63 "APLP1,THSD7A,INA,IGDCC3,DCC,EBF1,SEZ6L2,ELAVL3,NRN1,ACSL4,GAP43,GFRA1,GNG3,STMN2,IGFBPL1,KIF5C,MAP6,SCG3,TAGLN3,NCAM1,NEFM,PCSK1,PRTG,ARID4A,RGS10,ROBO1,RTN1,TNFRSF19,SCG5,SNCA,SYT4,TAC1,CNTN2,STMN4,SLC17A6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.60E-12 8.17E-09 1.98E-11 1.81E-10 49 108 "TTYH1,SLITRK1,SHTN1,ATP2B2,DIRAS1,ADGRG1,SRSF11,SCRN1,DCC,DTNA,FSD1L,OLIG2,EPHB1,ADGRV1,CLVS1,ZIC4,FOXG1,AFF2,DLL3,SRRM4,GRIK2,TOX2,FRMD5,IGFBPL1,CELF5,ATCAY,KCNH2,MAP2,SHC3,TAGLN3,MAPK10,ASRGL1,CXXC4,SOX11,GSE1,SYT11,SYP,TMEM178B,WSCD1,ACSL6,CUX2,CLASP1,FRYL,TUB,MGAT5B,ZIC1,DPYSL5,WNK2,FZD3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.92E-12 9.80E-09 2.37E-11 2.16E-10 30 49 "SLC7A14,CACNA1B,INA,CHGB,CNR1,CNTN1,MYRIP,PLCXD3,DNAJC6,GRIN3A,ELAVL2,ELAVL4,DNER,GPR22,STMN2,KIF5C,MAP4,NCAM2,NEFM,NTRK2,SLC10A4,NALCN,MAPK10,PRPH,RET,RGS4,RTN1,SNAP25,SCN3B,C11orf87" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000_k3 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.17E-12 1.11E-08 2.67E-11 2.44E-10 80 225 "RNF157,PNMA8B,INTS2,PKP4,ARHGAP5,DOCK11,BACH1,SGCE,SRSF11,CHM,SLIT2,PLAA,NMT2,COL4A5,RBM39,DOCK4,FGFR1OP2,GAPVD1,TCAF1,AIF1L,ZC3H11A,ABI1,EDNRA,EIF4G1,EMX2,EPB41L2,MEX3B,ANKFY1,SMC2,APOPT1,GABRA4,GABRB1,TUBGCP4,SRCAP,LPAR4,NR3C1,MIER3,MAP4,CHIC1,MEIS2,MMP16,SAMD5,MYO9A,NASP,CNOT4,PDPK1,PMS2,KANSL1,MAPK8,C1orf54,TMLHE,TRA2B,CHD9,SLC12A2,SCMH1,ZKSCAN3,SNCA,ZC3H13,KIF1B,TROVE2,KLHL4,AHCYL2,CBX5,ACTR6,R3HDM1,TSC1,SSBP2,UBE3A,FLRT2,RICTOR,ZNF711,EMX2OS,ADAMTS9,NAV2,SNX27,KCNAB1,FIP1L1,JMJD1C,GAN,SENP7" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.25E-12 1.15E-08 2.76E-11 2.51E-10 40 79 "TTYH1,ATP2B2,ADGRG1,SRSF11,SCRN1,DCC,ELAVL3,OLIG2,ADGRV1,CLVS1,FABP7,ZIC4,SPSB4,FOXG1,DLL3,SRRM4,GRIK2,RNF165,CELF3,TOX2,FRMD5,IGFBPL1,ATCAY,ZIC5,HES5,MAP2,SHC3,NRCAM,MAPK10,NPAS3,FGD4,WSCD1,FRYL,MGAT5B,ZIC1,ZIC3,DPYSL5,STMN4,STOX2,FZD3" Coexpression Atlas Arv_EB-LF_2500_K2 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 2.55E-12 1.30E-08 3.12E-11 2.85E-10 240 960 "CSMD2,CCDC85A,BEND6,PCDH19,KCTD16,SORCS2,SRPX,AMPH,DPP10,LRCH2,CNIH2,APLP1,APOC2,LRRC4C,LGR5,ARSE,ASCL1,INSYN2B,SLC4A4,RNF182,NRP2,CACNA1G,MYRF,CDK5R2,CABP7,VSTM2A,CBLN1,CCK,CDH8,CDH10,LGI1,CDR1,LHX2,TMEM59L,CNR1,CNTFR,COL11A2,AKAP5,IGDCC3,CRHBP,HAPLN1,SNCAIP,TENM4,MICAL2,ATRNL1,NCAN,CTNND2,PYGO1,DCC,DCT,LYPD1,PLPPR4,SPOCK3,DLX1,DNAH9,DRP2,DUSP9,EBF1,USH1C,EDIL3,SEZ6L2,EDN3,SEMA3D,EFNA2,ELAVL2,ELAVL3,ELAVL4,EMX2,EN2,LRRC17,EPHA5,EXTL1,CLVS1,TMEM132C,ZIC4,ACTL6B,HPCAL4,C1orf61,FOXF2,FLT1,PSD2,NSG2,DACH2,PHYHIPL,GABRA2,ILDR2,GAD2,GAP43,SRRM4,CPLX2,DNER,GFRA1,GFRA2,FREM1,GHR,GJB1,RUNDC3A,PCSK1N,GNG3,GPM6A,CCDC184,STMN2,GRIA1,GRIA2,C1QL4,GRIK1,GRIK2,GRIN2D,GRM8,PTPRT,ADAMTS6,CELF3,WIF1,NXPH2,BACH2,SCRG1,HPSE2,HMX1,IGFBPL1,C2orf72,LIX1,SCRT2,SLC6A17,INSM1,OLFM3,CDH20,KCNK2,KCNMA1,KCNQ3,LRRC4B,CLEC18A,MAP6,MATN2,CCDC80,TAGLN3,MTTP,RSPO2,LAYN,MYT1,NCAM2,NEFM,NELL1,NELL2,NHLH1,NNAT,NPY,NTRK2,DDR2,OLR1,OXTR,KCNK10,PAK3,PAX6,PCDH8,PDE1A,PDGFRA,ENPP2,PENK,GDAP1L1,HMGCLL1,PDZRN4,TRHDE,PRRX1,NECAB2,MAGEL2,POU3F2,POU3F4,NKAIN4,PRPH,MASP1,PSD,SYTL2,LAMA1,ELOVL2,PTPRD,PTPRH,PTPRN,PTPRO,PTX3,TMEM255A,RFX4,RGS4,ZFHX4,HUNK,KCNIP1,RTN1,AMER2,LRFN5,SCN3A,LINC00461,TNFRSF19,SEC31A,ZNF365,PKNOX2,LRRC55,TRIM67,SLIT1,DMRTC1,RIMS1,SNAP25,MYT1L,SOX5,ENKUR,PEG10,CLSTN2,SST,NACAD,SYT4,SYT5,TAC1,TAC3,CNTN2,ADGRL3,PCDHGB6,TF,CRB1,ASXL3,DAAM2,RIMBP2,SEZ6L,DOK6,TMEFF2,CADM1,FLRT1,FAM181B,ZIC1,FMN2,PLPP4,CRB2,MKRN3,DPYSL5,CA10,STMN4,SCG2,SLC17A6,DNAH10,PAK5,ST8SIA2,SLC4A10,PRRT4" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.67E-12 1.36E-08 3.26E-11 2.97E-10 118 386 "FMNL2,KLHL13,NR0B1,SPARCL1,ALCAM,ARHGAP20,APOC1,LGR5,PPP4R4,ZSCAN18,INSYN2B,TMEM108,SLC4A4,MYRF,CACNB2,CALB1,CDH10,DCLK1,MAGI1,CLU,CNTFR,AKAP5,ZNF521,CLIP3,ATRNL1,PLXNA4,BOC,DOCK4,DAPK1,DCT,MAGI2,SRGAP3,DNM1,DRP2,TSPAN5,EDNRA,KLHL5,EGFR,PLXNC1,EMX2,MTSS1L,NRN1,FAM198B,FABP7,FLNC,AFF2,NSG1,GABRA4,GABRB1,GFRA2,FREM1,GLI2,PCDH11X,GPR37,GUCY1A2,GUCY1A1,TCEAL6,SHISA6,IGF1,NKD1,KCND2,KLHL23,MAP2,MATN2,MEIS1,KITLG,MOV10,CCDC80,MTR,NEFM,NFIA,NME4,PCDH9,PDE1A,PDGFRA,CDK14,SERPINI1,PCDH18,PRRX1,FAT3,LAMA1,GDPD2,PTN,TMEM255A,ROBO2,TMEM206,LGR4,MEG3,HUNK,KCNIP1,SEMA6D,PRCD,TNFRSF19,SOX6,STUM,RASA3,CNKSR2,ST8SIA1,SLC4A3,PALLD,KDM3A,UHRF1BP1L,PEG10,SMOC1,ST5,ADGRL3,OBSL1,TEX15,ZFPM2,ACTR6,DAAM2,TNNT1,TRPS1,FNDC5,VSNL1,LYPD6,WNK3,DPF3" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000_k2 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.78E-12 1.42E-08 3.40E-11 3.10E-10 76 210 "ADD3,PNMA8B,TAOK1,PKP4,ARHGAP5,BACH1,SGCE,RUNX1T1,ZNF445,SRSF11,CHM,SLIT2,NMT2,COL4A5,RBM39,FGFR1OP2,TCAF1,AIF1L,ZC3H11A,CDON,EDNRA,EIF4G1,CALCRL,EMX2,EPB41L2,SRRM1,MEX3B,SMC2,APOPT1,GABRB1,ILDR2,TUBGCP4,SRCAP,TNRC6A,LPAR4,NR3C1,MIER3,MAP4,CHIC1,MMP16,SAMD5,NASP,CNOT4,PCDH9,OLA1,PIK3R1,PLEC,KANSL1,MAPK8,TMEM255A,C1orf54,RNASEL,TMLHE,MEG3,TRA2B,SLC12A2,SCMH1,SNCA,ZC3H13,KIF1B,TROVE2,PRRC2C,SYNE2,ANKRD12,WASHC4,PCDHB9,AHCYL2,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,ADAMTS9,NAV2,SNX27,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Subtype_eNb4_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 2.85E-12 1.45E-08 3.47E-11 3.16E-10 36 67 "APLP1,THSD7A,INA,IGDCC3,DCC,EBF1,SEZ6L2,ELAVL3,EPB41,NRN1,DLL3,GAP43,GNG3,STMN2,IGFBPL1,INSM1,KIF5C,MAP6,SCG3,TAGLN3,NCAM1,NEFM,NEUROD1,NHLH1,PRTG,C1orf54,RGS10,RTN1,TNFRSF19,SLC6A8,SYT4,TAC1,CNTN2,FNDC5,PCBP4,SLC17A6" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000 FaceBase_RNAseq 2.96E-12 1.51E-08 3.59E-11 3.27E-10 246 991 "ACTN2,ARID1A,SLITRK1,FAM135A,PKP4,APC,APOC1,APOC2,CDC14B,SPTBN4,ZFYVE28,ARHGAP5,ARRB2,PDE8B,DACT3,NUMB,ASTN1,ATP1A3,ATP2B2,DOCK11,BARD1,BBS2,MPDZ,SEC11C,BLM,ZNF599,JAZF1,GPC2,IL33,CA12,HAP1,PTBP2,MAP7,CBLN1,CDK11B,LRBA,ARHGEF2,KCNAB3,CCPG1,ADGRG1,SRSF11,LHX2,COG1,TJP2,VAX2,NIPBL,IQCK,PCYT1B,COL9A1,SLC4A7,IGDCC3,HAPLN1,CRYBB1,CLIP3,CRYM,SNCAIP,PLCH2,FAM169A,ST18,FGFR1OP2,KATNAL2,TOX,JAKMIP2,C8orf34,GSDME,DDX46,FAM107B,DLX1,DUSP9,MAMLD1,DYRK1A,DNM1L,ABCC9,EDIL3,KLHL5,LPAR6,ELAVL4,MTSS1L,SLC43A2,CEP85L,ETV1,EYA1,NSRP1,WAC,TMEM132C,PTK2B,BAIAP2,HPCAL4,FOXG1,ZMYND15,AFF2,SYT3,CINP,SMC2,ATP2C1,STAU2,TMEM151A,ABLIM2,OGA,NEURL4,BRPF3,ARPP21,GAP43,HIGD1B,C15orf41,SRRM4,KIAA1841,NTNG2,ZNF276,TXNL4A,COPS8,PCDH11X,KIAA1958,GOLGB1,GPM6A,CECR2,GRK4,PCLO,GRIK2,CIT,MFSD2A,GUCY1A2,TOX2,HLF,HPSE2,IGFBPL1,USP51,ICA1,IGF1,ZIC5,KNDC1,SCIN,LIX1,INSM1,ZNF385B,LRRTM3,KCNJ5,KIF5C,KIT,KTN1,LIMS1,PAXBP1,GPR155,MAN2A2,MAP2,SHC3,CPNE9,SAMD5,ADAM22,BCO1,RSPO2,MYCN,MYT1,TCEAL5,NASP,NFE2L2,NPY,CLEC9A,NRGN,ODF2,GPR137C,PAX6,PCMT1,PRTG,PDE4D,SSH1,PRIMPOL,PRRX1,KANSL1,DIRAS2,CNTLN,ELOVL2,C1orf109,STRC,PPP2R3C,RAP1GAP,NWD1,ENOX1,ARID4A,FEZF2,GAL3ST4,ZYG11B,DUSP15,REV3L,RFX4,KIF7,ZFHX4,MYH14,PLPPR3,CLIP1,DGLUCY,LINC00461,CASC3,GALNT10,SCG5,KIF21A,SLC1A2,PREX2,DHX30,SEPHS1,TET1,SMARCC2,CDK5RAP2,LIMCH1,SPATA7,BDP1,SOX11,ARHGAP26,RBM26,LMO3,SAMSN1,STAU1,SYNE2,MMS19,ROBO3,TAF9,TCEA1,SATB2,SYNE1,PHF24,ARHGEF12,SIRT1,LEFTY2,TIAM1,BHLHB9,NR2E1,TMOD1,AMACR,TRO,STXBP4,TRPS1,ZKSCAN5,UCHL1,CLIP2,ZNF711,ZNF23,WNK1,PMEPA1,STMN4,TMEM163,DNAH10,KAT6A,HNRNPA3,CERS6,FRMD6,SENP7" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k2 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.26E-12 1.66E-08 3.94E-11 3.60E-10 94 284 "PNMA8B,PKP4,ASPH,ATP2B1,RNF182,DOCK11,BACH1,SGCE,RUNX1T1,LDB2,ZNF445,SRSF11,SLIT2,PLAA,FAM171B,TENM4,GAPVD1,TCAF1,AIF1L,GIT2,ZEB2,ZC3H11A,CACNG7,APH1A,EIF4G1,EPB41L2,SRRM1,MEX3B,ANKFY1,NBEA,SMC2,APOPT1,SRCAP,GLRB,PCDH11X,LPAR4,DIDO1,GRIK1,PRDM5,CIT,KAT7,WIF1,HAS2,LSAMP,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,MYBPC1,NASP,OCRL,PCDH9,GPR85,PIK3R1,PRRX1,SDK2,KANSL1,MAPK8,PTN,TMEM255A,RNASEL,ROBO2,MEG3,NCBP3,ATXN2,TRA2B,CHD9,TET1,ARFGAP1,ZKSCAN3,ZC3H13,KIF1B,TROVE2,PRRC2C,SYNE2,KLHL4,HIF3A,CBX5,R3HDM1,TRPS1,SSBP2,UBE3A,FLRT2,PCDH20,ZNF142,NAV2,SNX27,FIP1L1,JMJD1C,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.29E-12 1.68E-08 3.98E-11 3.63E-10 26 39 "TMCC3,SYT13,ANK3,CALB1,INA,CHGB,ELAVL3,TMEM35A,NSG2,NSG1,GAP43,GNAO1,STMN2,CELF3,NEGR1,LSAMP,NCAM1,PBX1,RTN1,SCN2A,SCN3B,PEG10,SEPT3,VGF,CELF4,SCG2" Coexpression Atlas PCBC_ratio_EB_vs_SC_1000 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000 PCBC 3.32E-12 1.69E-08 4.00E-11 3.65E-10 247 997 "SERPINA3,NCKAP5,ADRA1B,PCDH19,AGT,KCTD16,SORCS2,SPARCL1,PCDH10,LRRC4C,LGR5,ASCL1,DACT3,INSYN2B,TTLL9,TTC9B,MYRF,CDK5R2,LDLRAD4,CABP7,THSD7A,CAMK2A,LGI1,NOG,ADGRG1,SLIT2,LHX2,CNR1,CNTFR,AKAP6,ABI3BP,CRHBP,HAPLN1,CSF3R,PLCH2,PHACTR3,PYGO1,ARHGAP24,DCC,DCT,ZNF804A,ZEB2,LYPD1,CCDC3,DLX1,DUSP9,EBF1,EDN1,EDN3,EDNRA,MBNL2,ELAVL3,CERCAM,ELAVL4,EMX2,DMTN,ERBB4,NCALD,NRN1,CLVS1,FAM198B,TMEM132C,ZIC4,DLC1,ZMYND10,FOXF2,FLNC,PSD2,NSG2,DACH2,ADGRA1,TPPP3,PHYHIPL,ILDR2,CPLX2,GFRA1,FREM1,PCDH17,GGT5,GHR,DCLK2,GP1BB,CCDC184,GPER1,STMN2,GRIA2,C1QL4,GRIK1,GUCY1A1,ATOH8,CELF3,UBE2QL1,FRMD3,SCRG1,SYNPO,C2orf72,IGF1,NKD1,KIAA1755,HES5,LIX1,IL6ST,SCRT2,IL11RA,INSM1,LRRTM1,NME9,ITIH2,KCNA2,CDH20,KCND3,KCNJ3,KCNK3,LMO2,SYTL4,SMAD9,GPR155,CLEC18A,C1orf194,MAP6,MAPT,LRP1B,MEIS1,MEIS2,SAMD5,CCDC80,TAGLN3,RSPO2,MDGA1,MYBPC1,MYH6,MYL3,RTL5,MYT1,NCAM1,NELL1,NFIX,NHLH1,NPPA,NTRK2,DDR2,OLR1,PAX6,PDE1A,PDE1C,PDGFRA,GPR85,PENK,PLCL1,HMGCLL1,PDZRN4,PMP22,PRRX1,POU3F2,LRRN3,VSTM2L,PRPH,RELN,PTHLH,PTH1R,PTPRH,RIPOR1,FAT4,ENOX1,MORC4,RFX4,RGS4,ZFHX4,ROBO2,RPE65,TMEM100,MELTF-AS1,WLS,RTN1,RXRG,AMER2,SCN3A,LINC00461,TNFRSF19,SMPD3,PEAR1,SOX6,CCDC92,SYBU,TRIM67,SLIT1,SLN,DMRTC1,SMARCD3,SNAP25,CABCOCO1,ANKFN1,SCN3B,ENKUR,NPAS3,CLSTN2,ITPRID2,SST,SYT4,CNTN2,VWA3A,ZEB1,PCDHGB6,AZIN2,TF,DNAH7,TMEM121,ZFPM2,RP9P,HHIP,HEY1,ASXL3,TLR4,RIMBP2,TNS1,DOK6,SYNPO2,TRH,LRRC24,PPIL6,FNDC5,RFTN2,AMOT,FLRT2,FAM181B,TOM1L2,WNT7A,ZIC1,CFAP52,EMX2OS,PLPP4,CRB2,ZBTB16,STMN4,PRDM8,ADAMTS9,SCG2,SLC17A6,DNAH10,FAM13C,MSRB3,SLC39A12,KLHDC1,DPF3,CBLN2,FAM181A,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 3.34E-12 1.71E-08 4.02E-11 3.66E-10 24 34 "SYT13,VAT1L,SEPT7,CHGB,ARHGAP32,SEZ6L2,ELAVL3,GAP43,GPM6A,STMN2,CELF3,CELF5,LSAMP,PAK3,TMOD2,PPP2R2B,SNAP25,SCN3B,PEG10,SEPT3,VGF,CELF4,STMN4,SCG2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.40E-12 1.73E-08 4.08E-11 3.72E-10 29 47 "DPP10,ADAM23,CACNA1B,CDH10,CNR1,COL9A1,PLCXD3,GRIN3A,CALN1,TUBB3,ATP8A1,SYT17,GFRA2,KCNMA1,KIF5C,MAP4,RSPO2,NDP,NTRK2,CLDN11,MAPK10,PRPH,PTPRO,RGS4,RTN1,SNAP25,SCN3B,C11orf87,CUX2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.64E-12 2.37E-08 5.55E-11 5.06E-10 73 200 "ADCY2,PNMA8B,KLHL13,NR0B1,CC2D2A,LRRC4C,IGDCC4,TMEM108,MYRF,CACNB2,REPS2,DCLK1,AKAP5,ZNF521,CLIP3,TENM4,ATRNL1,PLXNA4,BOC,SV2A,SRGAP3,DLG4,DNM1,DRP2,C8orf37,EMX2,MTSS1L,NRN1,TUBB4A,MEX3B,FLNC,NSG1,GABRA4,TRAF3IP2,PCDH11X,GUCY1A2,TCEAL6,IGF1,NKD1,KCND2,KLHL23,MAP2,MATN2,MEIS1,NEXMIF,NFIA,NNAT,NME4,PDE1A,PCDH18,PRRX1,PTPRD,REV3L,LGR4,MEG3,HUNK,ZNF354C,CCDC112,SATB1,RASA3,PDZD2,ZCCHC24,PEG10,ST5,ADGRL3,EHBP1,PSD3,ZFPM2,ASXL3,TNNT1,TRPS1,PLEKHH2,ZFP37" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K2 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 4.84E-12 2.47E-08 5.78E-11 5.27E-10 37 71 "SLITRK1,FGF17,HAP1,INA,ADGRG1,NCAN,KBTBD11,EPHB1,ADGRV1,REEP2,FABP7,SPSB4,AHCYL1,STMN2,GRIK3,RNF165,CELF3,TOX2,FRMD5,ZIC5,HES5,NRCAM,POU3F4,MAPK10,PROX1,RTN1,HSPA4L,SCG5,SOX2,WSCD1,ACSL6,MGAT5B,ZIC1,ZIC3,DPYSL5,FZD3,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Subtype_iProg1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.26E-12 2.68E-08 6.26E-11 5.71E-10 35 65 "SYT13,ANK3,KIF1A,SEPT7,CDC25B,CRMP1,SLC45A1,KIAA0408,SEZ6L2,ELAVL3,PRMT5,NSG2,NSG1,PNMA2,GAP43,GNAO1,GPM6A,STMN2,CELF3,BEX5,NCAM1,RTN1,SCN3A,SNAP25,MAPKBP1,SCN3B,PEG10,SS18,SYT4,MTMR14,VGF,CELF4,REEP1,STMN4,SCG2" Coexpression Atlas PCBC_ctl_geo-heart_1000 geo_heart_top-relative-expression-ranked_1000 PCBC 5.77E-12 2.94E-08 6.85E-11 6.25E-10 246 997 "SERPINA3,TKTL1,ACTN2,NDRG2,GALNT16,ADCY5,HHATL,ADORA3,LCNL1,DPY19L2P4,AGT,HFM1,C1QTNF1,ADGRF5,SPARCL1,CARNS1,ANK1,FGD2,PI16,MYH7B,DDO,CPNE5,SPTBN4,PLA2G4C,ATP1A2,ATP1A3,B3GALT2,MYOM1,AZGP1,RGS11,DNAJC27-AS1,GPR146,LDHD,C1QC,CA4,CACNB2,DIRAS1,CAMK2A,CAMK2B,VXN,USP2,RGN,ENTPD2,MYOM2,LONRF2,CHGB,CHI3L2,MS4A7,LSMEM2,FAM189A2,AKAP6,CABP1,TOGARAM2,NRG2,CRYM,CSF1R,CSF3R,PDE4DIP,PHACTR3,CMTM5,PLCXD3,CFAP61,CYBB,DGKG,DMPK,ECM2,EEF1A2,HEYL,SRPK3,ELN,RCAN2,DMTN,RASGRP2,KCNMB2,RAB9B,DUSP27,RCSD1,NRN1,F5,ABCA8,TMEM132C,FCGR3A,FGF1,FGF12,FGR,FLNC,FOLR2,C2orf88,SORBS1,KBTBD12,ABLIM2,DKK3,CHL1,GALNT15,IP6K3,HIGD1B,ACSS1,CPLX1,MYOZ2,ALDH1L1,TUBA8,CYP46A1,GFAP,CSDC2,GGTA1P,GGT5,PPARGC1A,LYVE1,GP1BB,LILRB4,GPD1,DIPK1C,GPR17,GPR22,TPPP,PLPP7,GRIN2C,GSN,FAM107A,GUCY1A1,LINC01550,UBE2QL1,HBA1,FRMD3,INSYN1,HLF,VSIG4,HAPLN2,SYNPO,HP,HPR,ALDH1L1-AS2,IRF8,FAM95B1,IGF1,KIAA1755,ITGA7,ITGAM,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ11,KCNK3,PACRG,MAOB,MAPT,COL28A1,MT3,CTNNA3,MYBPC1,MYH6,MYH7,MYL3,NCAM1,NFIX,NPPA,NTRK2,PDE1A,PDE1C,PDE2A,PDE3A,PGAM2,DUSP26,PHKG1,RETREG1,PLCL1,PLIN1,FXYD1,PRRX1,SEPT4,PACSIN1,PPP1R1A,MAPK4,FITM2,PROX1,MASP1,PTH1R,DKFZp779M0652,PTPRB,PYGM,SUSD4,CRTAC1,PRIMA1,RNASE1,MYH14,GLDN,SGSM1,SYNDIG1,KCNIP2,RXRG,HOGA1,SCN2B,SCN4B,SCN7A,MRAS,SH3BGR,FHOD3,ABLIM3,SLC4A3,SLC1A7,SMTN,LIMS2,SLC8A1,SLC11A1,SLC14A1,SPHKAP,SLN,IGSF9B,FAIM2,PDZD2,IDI2-AS1,SPTB,CLSTN2,ADHFE1,ABCC8,COBL,VWC2,PCDHGC5,PCDHGA6,PCDHGA3,PCDHGA2,ARHGAP9,HIF3A,TF,THBS4,TIMP4,TMOD1,TNS1,RASD2,TPM1,SYNPO2,FNDC5,ANO5,VIPR2,ETNPPL,LGI4,NDRG4,REEP1,SLC30A3,SHD,WNK2,ADAMTSL3,SSPN,DPF3" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000 DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.29E-12 3.72E-08 8.64E-11 7.88E-10 201 778 "TKTL1,RNF157,ADD1,ADD3,PNMA8B,ADORA1,PWWP2A,INTS2,NR0B1,TAOK1,LCORL,PKP4,DGKD,LGR5,MADD,ARHGAP5,PLA2G4C,PDE8B,ASPA,DDX3Y,INSYN2B,ATM,ZNF583,RNF182,DOCK11,BACH1,SYNJ1,SCAPER,SGCE,BTRC,CALB1,CDC42,SRSF11,CHM,SLIT2,KMT2C,PLAA,NMT2,CNR1,COL4A5,AKAP5,RBM39,FAM169A,DZIP3,APPL1,GREB1,PUM1,DOCK4,HDAC9,FGFR1OP2,GAPVD1,TCAF1,AIF1L,MAGI2,TMEM130,ZC3H11A,GSDME,SACS,DYNC1I1,CPEB2,ABI1,DRP2,DTNB,DNAJB6,EDNRA,ATL1,RASGRP1,EIF4G1,ELAVL2,EMX2,EPB41L2,CD320,NRN1,SCML2,ATP8A1,KIAA1109,MEX3B,ANKFY1,SMC2,APOPT1,PDLIM5,ATP6V1H,PHYHIPL,GABRA4,GABRB1,ILDR2,GATM,TUBGCP4,SRCAP,AIFM3,MAP7D2,TDRKH,GPR19,LPAR4,GRK4,TPPP,NR3C1,KIF3A,MAEL,MIER3,ZNF385B,KCND2,HECTD2,MAP4,CHIC1,MEIS2,KITLG,MMP16,SAMD5,DDX25,MTR,MYO5A,MYO9A,NEXMIF,NASP,CNOT4,GPR137C,GLIPR1L2,PDPK1,SERPINI1,JAKMIP1,PLP1,RC3H2,PMS2,C19orf57,PPP2R5E,PPP3CC,KANSL1,MAPK8,ANKHD1,EML5,C1orf54,TMLHE,ATP8B4,ACER3,MEG3,PRCD,FNIP1,TNFRSF19,SFPQ,TRA2B,HSPA4L,ARX,CPEB3,CHD9,SYBU,WDR47,SLC12A2,SCMH1,CPEB4,ZKSCAN3,ZNF667,SNCA,SOX2,SOX5,SP4,ZC3H13,ARHGAP26,KIF1B,RBM26,TROVE2,LARP4,SYNE2,VPS13A,SYN2,SLC37A2,ANKRD12,KLHL4,DMXL2,AHCYL2,TEX15,SIRT1,CBX5,ACTR6,R3HDM1,NR2C2,RUNDC3B,TSC1,SSBP2,UBE3A,UGT8,FLRT2,TBC1D15,VSNL1,RICTOR,ZIC3,ZNF711,ZNF23,EMX2OS,LYPD6,REEP1,ADAMTS9,NAV2,SNX27,KCNAB1,FIP1L1,PHTF2,JMJD1C,RSPRY1,GAN,SENP7" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.94E-12 4.05E-08 9.39E-11 8.56E-10 199 769 "KDM5D,ADCY2,PNMA8B,GRAMD1B,KLHL13,NR0B1,SORCS2,ALCAM,ARHGAP20,LTBP4,AMH,SEMA7A,GAS7,GPAM,LGR5,CDC14B,PPP4R4,TMEM263,IGDCC4,CADPS,DDX3Y,ATP1A1,ALDH7A1,CACNA1G,CACNA2D1,ISPD,RUNX1T1,PRC1,ARHGEF25,CBLN1,LDB2,SCARB1,REPS2,CACNA2D2,ADGRG1,SLIT2,CLU,CNTFR,MAGED1,ZNF521,HAPLN1,TENM4,MICAL2,ATRNL1,VCAN,DZIP3,BOC,MYADM,RIPOR2,SCRN1,ARMCX2,ZEB2,SRGAP3,DNM1,DTNA,TSPAN5,EDNRA,SEMA3D,EGFR,MRO,PLXNC1,EPB41L2,LRRC17,EPS8,ERBB4,ETV1,EYA1,NRN1,FAM198B,FABP7,PTK2B,DLC1,FGF13,IP6K2,FLNC,AFF2,NOP56,CAMKK2,FYN,ZMAT1,GABRA4,TRAF3IP2,IQGAP2,SEPT9,GATM,GFRA2,FREM1,GHR,PPARGC1A,GLI2,PCDH11X,ADGRA3,GPM6A,GPM6B,FUT10,LPAR4,GPR37,GRIA4,PRDM5,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,DOCK7,KCNH1,KLHL23,LAMA2,MAP2,MATN2,MEF2C,MEIS1,MYO9A,NEXMIF,NCAM1,ZC3H12B,NEFM,NFIA,NNAT,PAK3,PCDH9,PCSK5,PDE1A,PDGFRA,SERPINE2,ANLN,PCDH18,PLTP,FAT3,SH3KBP1,LRRN3,PPP3CC,RASGEF1B,MASP1,LAMA1,PTCH1,PTN,TMEM260,ZIK1,PTPRD,PYGM,TUG1,TMEM255A,ZCWPW1,REV3L,RAVER2,ROBO1,ROBO2,TMEM206,PCMTD2,ARMH4,GLDN,ACER3,LGR4,MEG3,HUNK,SATB1,SOX6,MRAS,DOCK10,SMTN,PKNOX2,ATF7IP,ARFGAP1,PALLD,TNIK,ZCCHC24,UHRF1BP1L,SPP1,TSPYL2,SMOC1,ST5,SULF2,SYNE2,PJA1,ADGRL3,KLHL4,PSD3,OBSL1,ZFPM2,TGFBR3,HHIP,THRA,TIAM1,ASXL3,TNS1,TPM1,TRPC3,TRPS1,TST,TMEFF2,SGK3,PLEKHH2,VSNL1,CLDND1,STOX2,ADAMTS9,WNK3,NETO2,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 8.97E-12 4.58E-08 1.06E-10 9.63E-10 24 35 "ANK3,INA,SEPT7,CRMP1,EEF1A2,ELAVL2,ELAVL4,TUBB3,NSG2,NSG1,GAP43,STMN2,KIF5C,KLC1,TAGLN3,NEFM,NELL2,PCDH9,LRRN3,RTN1,SCN3A,SEPT3,UCHL1,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOMTN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.97E-12 4.58E-08 1.06E-10 9.63E-10 24 35 "ANK3,INA,SEPT7,CRMP1,EEF1A2,ELAVL2,ELAVL4,TUBB3,NSG2,NSG1,GAP43,STMN2,KIF5C,KLC1,TAGLN3,NEFM,NELL2,PCDH9,LRRN3,RTN1,SCN3A,SEPT3,UCHL1,STMN4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000_k3 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.15E-12 4.67E-08 1.08E-10 9.80E-10 91 276 "PNMA8B,TAOK1,LCORL,PKP4,ASPH,DOCK11,BACH1,SGCE,CDH2,SRSF11,CHM,SLIT2,KMT2C,PLAA,NMT2,RBM39,TENM4,FGFR1OP2,GAPVD1,TCAF1,AIF1L,G3BP2,EIF4G1,EMX2,EPB41L2,SRRM1,KIAA1109,ANKFY1,SMC2,APOPT1,ILDR2,SRCAP,PCDH11X,LPAR4,DIDO1,NR3C1,PRDM5,KAT7,MIER3,NKD1,MAP4,CHIC1,MID1,MMP16,MSI1,NASP,CNOT4,OCRL,PDPK1,PLEC,PMS2,KANSL1,MAPK8,TMEM255A,MSANTD2,TMLHE,PCMTD2,NCBP3,SATB1,ATXN2,FNIP1,TRA2B,CHD9,FNDC3A,SLC12A2,SCMH1,CPEB4,UNC5B,ZC3H13,KIF1B,TROVE2,CLSTN2,SYNE2,ANKRD12,AHCYL2,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,TBC1D15,ZFP37,ZNF711,TRIM9,ADAMTS9,NAV2,SNX27,FIP1L1,JMJD1C,GAN,SENP7" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.99E-12 5.10E-08 1.17E-10 1.07E-09 136 474 "ACLY,ABHD6,KDM5D,TMCC3,ADORA1,KIAA1324,BCAR3,AMH,SEMA7A,GAS7,KIAA1614,TMEFF1,ARHGDIG,CADPS,ATP1A1,N4BP2L1,DPY19L3,BCHE,ZNF599,DST,ST3GAL5,SYNJ2,DDR1,RGN,CACNA2D2,ADGRG1,CLU,CLTB,SUMF2,COL9A3,MAGED1,CP,NCOR2,CST3,ARHGEF4,SCRN1,JAKMIP2,PLPPR4,CD99L2,RCAN1,DTNA,DTNB,MAMLD1,E2F6,SIDT2,MRO,PLXNC1,SORBS3,CERCAM,EPS8,ERBB2,ERBB4,RASL12,EYA1,F3,REEP2,PTK2B,TUBB3,EFEMP1,FGF13,FHL1,SEMA6C,FOXO3,CAMKK2,CSPG5,FAM184B,BRPF3,ERAP1,SEPT9,GATM,PPARGC1A,ADGRA3,GPM6B,STON1,GPR37,MFSD2A,PADI2,HSD17B1,DOCK7,KCNH1,SYTL4,HECTD2,NCOA7,MAN2A2,PPM1L,MOV10,MSI1,NRBP2,CTNNA3,MYO7A,FXYD6,NELL1,NRDC,OCRL,CLDN11,PAK3,PGAM2,SERPINE2,SSH1,PLCB2,MTRF1L,SCHIP1,RASGEF1B,EPDR1,MASP1,SH3TC2,DUSP15,ROBO1,PCMTD2,GLDN,RPS6KA2,SOX8,SOX6,MRAS,SH3GL2,DOCK10,ST6GAL1,SLC6A8,EFHD1,TNIK,SOX10,SPP1,ADHFE1,SYNE2,TACC1,SEMA4A,SIN3B,THRA,TIAM1,SGK3,LMF1,SLC38A1,ADAMTS9,FZD3,NHSL1,GAN" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.15E-11 5.88E-08 1.35E-10 1.23E-09 206 806 "ACTN2,SLITRK1,SORCS1,C1QTNF3,ALAD,ARHGAP20,BBOX1,AMPD3,ANK1,ANK2,VAT1L,APOC2,BCAS1,ARRB1,MYOM1,ADGRB3,GPR146,IL33,MMD2,CA8,CAST,CH25H,RUNX1T1,RGN,MYOM2,CDC25B,DCLK1,UBE2L6,CHGB,RAB3C,CNTN1,PCYT1B,AKAP6,COL9A1,COL9A3,ABI3BP,IFFO1,MYRIP,CPS1,CRMP1,CRYM,NRSN1,SCRN1,DNAJC6,SNAP91,RABGAP1L,TMCC2,GRIN3A,DUSP9,EBF1,ST8SIA3,SGK2,EFNA3,SH3GLB1,AASS,ELAVL4,SRPK3,PCOLCE2,EPB41,DMTN,PIPOX,EYA1,NRN1,F5,FABP7,CORO2B,FECH,POLR1B,UBE2E3,FOXG1,CAP2,FOXO3,SPECC1,PDLIM5,PNMA2,TPPP3,MEGF10,GABRA1,BRPF3,ARPP21,GAP43,ACSS1,CPLX1,DNER,MYOZ2,ALDH1L1,GFRA2,LYVE1,RAB40B,GNG4,STMN2,GRIA1,GRIA4,GRM3,GRM7,GSN,FAM107A,MAEL,UBE2QL1,ARHGAP36,NEGR1,AGFG1,IFI16,C2orf72,IGF1,IGFBP1,IGSF1,SCIN,INSM1,ITIH2,KCNK2,LMO2,LSS,ASPRV1,PIK3AP1,MAOB,MAP4,MAPT,IL17D,MEF2C,MN1,MSR1,MTTP,MTR,MYBPC1,MYH3,MYH6,MYH7,MYL3,NEFM,NFIA,CLDN11,PAH,CNTN3,PCDH8,GPR85,PGAM2,JAKMIP1,PSAT1,PRRX1,CEP41,PKIA,MAPK10,DIRAS2,PRPH,MASP1,RELN,PTX3,MORC4,RGS4,ZFHX4,LGI2,ATP8B4,PRR5L,MEG3,RTN1,S100B,SALL1,CSRNP3,SCN7A,ELMOD1,SLC30A10,SOX6,SH3BGR,ARX,ABLIM3,SLA,YPEL4,SLC14A1,SPHKAP,SLC22A4,SLN,SNAP25,SNCA,SCN3B,SOX2,C11orf87,APOM,ADHFE1,SYN2,SYT1,COBL,TAL1,VWC2,ARHGEF12,ARHGAP9,HIF3A,VWCE,TF,THBS4,TMOD1,TNNT1,TPM3,SYNPO2,TTPA,PDIA2,VSNL1,ZIC1,ZIC3,AGMO,TCEAL7,SPIRE1,KCNAB1,RGS7BP,FAM13C,NETO1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_1000 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.16E-11 5.90E-08 1.35E-10 1.23E-09 215 850 "SDE2,ABAT,ACTN1,KDM5D,FMNL2,ADCY2,RNF150,HECW2,KLHL13,NR0B1,SPARCL1,ARHGAP20,GAS7,CACHD1,LRRC4C,LGR5,CDC14B,PPP4R4,CADPS,ZSCAN18,NUMB,RASL11B,DDX3Y,TMEM108,WASF1,MYRF,CACNB2,CALB1,KALRN,RUNX1T1,CBLN1,RGN,SLC16A4,CBFA2T2,CDH2,CDH10,DCLK1,CDH18,MAGI1,SLIT2,CLU,CNN3,CNTFR,AKAP5,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,FAM169A,NOS1AP,DOCK4,DAPK1,SCRN1,DCT,TIAM2,MAGI2,POM121,SV2A,SRGAP3,DNM1,CPEB2,DRP2,DTNB,EDN1,EDNRA,SEMA3D,EGFR,MRO,PLXNC1,AASS,LPAR6,SORBS3,C8orf37,EMX2,MTSS1L,F3,ABCA8,FAM198B,FABP7,PTK2B,TUBB4A,CAP2,FLNC,AFF2,CAMKK2,NSG1,FYN,GABRA1,GABRA4,GABRB1,TRAF3IP2,DENND2A,NEK6,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,ADGRA3,GPM6B,GPR37,BVES,GUCY1A2,GUCY1A1,HAS2,TCEAL6,SHISA6,NKD1,TUBB2B,KCND2,KCNH1,KLHL23,MAP2,MATN2,MEIS1,KITLG,AFF1,CCDC80,DDX25,CTNNA3,MTR,MYBPC1,TCEAL5,NCAM1,ZC3H12B,NEFM,NFIA,NME4,PAK3,PDE1A,PDGFRA,PFKFB3,SERPINI1,PIK3R1,ZNF655,PCDH18,PRRX1,RASGEF1B,PRKCB,SYTL2,LAMA1,PTCH1,PTN,PTPN13,PTX3,TMEM255A,RBBP8,RADX,REV3L,ROBO1,ROBO2,TMEM206,GLDN,LGR4,MEG3,HUNK,SOX6,MRAS,RASA3,DOCK10,ST6GAL1,ST8SIA1,SLC4A3,PKNOX2,PALLD,TNIK,SOX5,ZCCHC24,KDM3A,UHRF1BP1L,PEG10,SMOC1,LRRC4,ST5,RGL1,SULF2,KLHL7,ADGRL3,PSD3,OBSL1,CCDC173,TEX15,DNAH7,ZFPM2,HEY1,ACTR6,ASXL3,HEY2,DAAM2,BEX4,TNNT1,TPM1,ZNF346,TRPS1,FNDC5,SSBP2,TST,TMEFF2,PLEKHH2,ZFP37,ZNF711,LYPD6,STOX2,ADAMTS9,NAV2,WNK3,FZD3,NETO2,DPF3,ST8SIA2" Coexpression Atlas Arv_SC-hpx_blastocyst_2500_K2 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.21E-11 6.19E-08 1.41E-10 1.29E-09 237 959 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,SLITRK1,ADCY8,GALNT13,NLGN4X,SEMA6A,UNC79,PDZD4,DPP10,RASL11B,KIF1A,CARMIL3,RGS9,GYG2,HAP1,SYT6,BRSK2,MAP7,CLDN10,SYNGR3,DLGAP1,CACNA2D2,CHGA,RAB3C,DLGAP3,SLC24A2,FAM189A2,FAM19A5,SULT4A1,IGLON5,CABP1,COL9A1,COL9A3,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,C1QL2,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,NOS1AP,LONRF1,RIMS3,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,RABGAP1L,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,AASS,LINC00599,ELAVL2,BSCL2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SPSB4,MAD2L2,HPCAL4,C1orf61,SYT3,CSPG5,B3GAT1,TVP23A,MEGF10,HRASLS5,GABRA5,GABRB3,JPH4,SALL3,SYT17,ATP8A2,SRRM4,TTBK1,RND1,TOX3,PCDH11X,GNG4,GPM6B,LPAR4,CECR2,GRIA4,ADAMTS8,KAT7,SOX21,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,PADI2,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,TUBB2B,LRRTM3,KCND2,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,SCAMP5,CPNE9,JAKMIP3,ADAM22,SCG3,DDX25,FXYD7,RCOR2,ZDHHC22,PAH,NLGN3,GDAP1L1,SEMA5B,CAMKV,PLP1,PNMA3,PSAT1,NECAB2,FA2H,FAT3,PPP2R2B,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,LGI2,ZNF532,RIMKLA,RYR1,SALL1,LRRTM4,TMEM200C,SCG5,SH3GL2,PPM1E,CNKSR2,BCAN,SLC1A6,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,OGDHL,IGSF9B,SNCB,SNRPN,SOX2,SOX3,NMNAT2,LHFPL4,HECW1,SOX21-AS1,SEPT3,NECAB1,FGD4,ZFR2,ARC,SYN2,COBL,TAC1,TAC3,UNC5D,WWC1,KLHL4,CUX2,TMEM151B,FAM189A1,CCDC173,SIRT1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,KCNE5,CA14,TUBB2A,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,SLC13A3,KCNK12,ZIC2,ZIC3,KCNT2,TMEM198,DPYSL5,PLPPR5,DHX33,CADM2,STOX2,XKR7,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k1 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.26E-11 6.43E-08 1.46E-10 1.34E-09 57 142 "ABAT,RNF150,OSBPL6,ARHGAP20,SYT13,DPP10,TNRC6C,NOL4,ADGRB3,VSTM2A,LGI1,CHGB,CNTN1,RIMS2,NTM,GRIN3A,EBF1,PLXNC1,MRVI1,DACH2,MEGF10,DNER,FREM1,GRIA1,GRIA4,GRM3,PTPRT,NEGR1,KCNA1,MMP16,MN1,NCAM1,NTRK2,DDR2,CLDN11,PDE1C,PRRX1,PTX3,ZFHX4,KIRREL1,MEG3,CSRNP3,LRFN5,SCN2A,ST8SIA1,SLC14A1,CXXC4,SORCS3,NEK4,SYT4,ANO4,PCDHB3,THBS4,RGMB,TMEFF2,MRPL47,NETO1" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k5_500 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.29E-11 6.57E-08 1.49E-10 1.36E-09 28 46 "APLP1,ASCL1,CRMP1,CSNK1E,GSDME,TUBB3,DPYSL4,DLL3,GAP43,STMN2,BACH2,INSM1,TUBB2B,KLC1,MAPT,NEFM,GNG2,ZFHX4,SCG5,SNRPN,SOX2,SOX11,GSE1,SYT11,TRIM2,ZIC1,PCBP4,VANGL2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.33E-11 6.77E-08 1.54E-10 1.40E-09 121 408 "EMILIN3,ADCY5,USP31,PCDH10,DPP10,ANK3,APC,TNRC6C,ASTN1,ADAM23,NRP2,BMP7,CDK5R1,DST,CACNA1B,CACNA1D,CACNA2D1,KALRN,RUNX1T1,MYOM2,CDH10,FAM171B,ANKRD44,CLIP3,SNCAIP,PLCH2,SIPA1L1,VCAN,PYGO1,TOX,JAKMIP2,ELMO1,ARNT2,GRIN3A,DNM1,HS3ST4,CALN1,DNM2,EDNRB,HIPK3,CACNG7,EGFR,ETV1,EYA1,TMEM132C,CORO2B,EFEMP1,KIAA1109,CAP2,FOXF2,SGIP1,DPYSL4,DACH2,DKK3,CHL1,IQGAP2,SYT17,GFRA1,GFRA2,PCDH17,PCDH11X,KIAA1958,B4GALNT4,GRIA2,GRM3,KLF12,BACH2,IFI16,IL17D,MKLN1,JAKMIP3,RSPO2,MYH3,MYH7,NDP,NEFM,NFIA,NFIX,CLDN11,PDE3A,GPR85,SSH1,TRHDE,PRRX1,FAT3,KANSL1,FAT4,REV3L,ZFHX4,ARMH4,RYR3,SALL1,SCN3A,TNFRSF19,NTNG1,SLC15A2,SOX2,ZHX3,NPAS3,SMOC1,EPB41L3,ARHGEF9,MTCL1,CAMSAP2,ADGRL3,CUX2,FAM189A1,PCDHB7,HHIP,TIAM1,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRPS1,RPRM,FMN2,TCEAL7,NUP214,MSRB3,ST8SIA2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.35E-11 6.88E-08 1.55E-10 1.42E-09 25 38 "PCDH10,INA,CHGB,TMEM59L,CNTN1,SPOCK2,BRINP1,DNAJC6,ELAVL2,TMEM35A,NSG2,GAP43,GNAO1,STMN2,GRIK2,RTN1,SCN3A,SCG5,SCN3B,MYCBP2,ERC1,SYT1,CELF4,PLPPR5,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hSert_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.35E-11 6.88E-08 1.55E-10 1.42E-09 25 38 "PCDH10,INA,CHGB,TMEM59L,CNTN1,SPOCK2,BRINP1,DNAJC6,ELAVL2,TMEM35A,NSG2,GAP43,GNAO1,STMN2,GRIK2,RTN1,SCN3A,SCG5,SCN3B,MYCBP2,ERC1,SYT1,CELF4,PLPPR5,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.37E-11 6.97E-08 1.57E-10 1.43E-09 103 329 "TTYH1,SPARCL1,LRRC4C,ASCL1,SEC11C,BMP7,ARHGEF7,THSD7A,VXN,PRC1,SEPT7,CDO1,SOCS6,JAM2,NRXN1,CLU,IGDCC3,TENM4,NCAN,CTNND2,TOX,DCC,LYPD1,EDNRB,EEF1D,PHF20L1,EN2,ADGRV1,FAM198B,FABP7,FDFT1,FGFR3,BAIAP2,C1orf61,SMC2,SPECC1,PDLIM5,MEGF10,ILDR2,NKX6-2,SALL3,RND1,NUDT21,STMN2,GRM3,TOX2,ELOVL5,HMGB1,SCRG1,HMGCR,BTBD17,HES5,FGFBP3,LSAMP,MEST,MN1,MSI1,MTTP,NASP,NELL2,NKX2-2,NNAT,NPTX2,NTRK2,CNTN3,PCDH8,PDPK1,PLP1,FAT3,POU3F2,IRX1,MAPK4,SLC22A23,LAMA1,PTCH1,PTPRO,C1orf109,PTPRZ1,PTX3,RALGDS,ARID4A,VEPH1,RFX4,SALL1,HES6,SFPQ,PUF60,LIMCH1,SOX1,SOX2,SOX3,NMNAT2,SYNE2,WWC1,ZEB1,TCF12,NSD1,TMPO,SEZ6L,WNT7A,LAMP5,PMEPA1,RGMA" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500 facebase_RNAseq_e10.5_Emin_LatNas_2500 Gudmap RNAseq 1.43E-11 7.32E-08 1.64E-10 1.50E-09 335 1459 "DPF1,TTYH1,ABCF1,ACLY,ARID1A,FMNL2,ADD2,KIAA1211,PCDH19,SEMA6A,CEP126,DOC2A,LRCH2,ANK2,APC,UPRT,ARHGAP5,ASTN1,ATM,NOL4,ATP6V0A1,KIF1A,BLM,ZNF599,CFLAR,PROM1,BMPR1B,FUBP1,WASF1,CA12,CACNB2,PTBP2,CANX,USP2,CDK11B,SEPT7,CDC27,CDH2,SRSF11,CHN1,JAM2,NRXN3,KIAA1549L,FAM19A5,C4orf33,QKI,NIPBL,CNTFR,AKAP7,IQCK,BTF3L4,SLC4A7,SLC4A8,AHCTF1,IGDCC3,SLC35F1,FAM171B,CREB5,CRMP1,CLIP3,CRYM,FEZ1,IPCEF1,CNTNAP2,FAM169A,DZIP3,PHF14,BOC,FGFR1OP2,KATNAL2,TOX,LIN54,KIAA0586,AIF1L,DDX46,MTX3,DMD,USP3,SLC29A4,CASP8AP2,DTNA,DUSP9,E2F5,FSD1L,EIF4G2,EIF5,ELAVL2,ELAVL4,EMX2,PLEKHO1,EPB41,COQ7,KCNMB2,ANKRD13B,SRRM1,ERBB4,ERCC2,CEP85L,ETV1,TLR7,CEND1,ADGRV1,NSRP1,WAC,FABP7,TUBB4A,CORO2B,FKTN,FDFT1,SPSB4,FGF12,CAMSAP1,FHL1,MEX3B,AFF2,NOP56,COQ5,ZCCHC17,SMC2,USP16,PRELID3A,KHDRBS3,FUT9,PHYHIPL,MTHFD2,ACSS1,GART,KIAA1841,TUBA8,GFRA2,GK,TCERG1,DBF4,GLI2,GLRB,TOX3,CBX1,GNAO1,GNG3,GPM6A,GPM6B,CECR2,GRK4,CNTRL,STMN2,GRIK2,CIT,RNF165,MFSD2A,PSIP1,GUCY1A2,CELF3,FRMD5,BACH2,HMGCR,HSF2,HSP90AA1,SMAP1,DOCK7,LRRCC1,LIX1,TUBB2B,KCNC1,KCNJ5,KCNJ16,KIF2A,KIF5C,KTN1,LIG4,SFXN5,LMO1,HECTD2,LSS,MAP2,MAP6,MARK3,TM6SF1,SHC3,MID1,POC1B,MSI1,TAGLN3,MYO5A,NAP1L1,NASP,NEFM,CNOT4,NOVA2,CLEC9A,NRCAM,NRDC,ODF2,PAK3,PDE3B,PDE1B,FAM98B,OLA1,ANLN,GPSM2,PPP1R1A,CRLS1,PKIA,MAPK4,MAPK8,LRRC49,CNTLN,ELOVL2,SPDL1,ZIK1,EML5,PTPRZ1,PTX3,NKAIN1,CCDC40,FAM184A,ARID4A,RBBP6,RBBP8,RADX,VEPH1,RDX,REV3L,ERI2,NUDT11,SETD5,MYH14,FBXW7,GLDN,RIMKLA,SOX8,CLIP1,RTN1,SALL1,FAM19A1,SCN8A,ZFP2,SOX6,SFPQ,TRA2B,HSPA4L,SCG5,ZFP30,KIF21A,PPM1E,CHD9,FHOD3,ST3GAL3,ST8SIA1,PREX2,DHX30,RUFY2,PKNOX2,YPEL4,CCDC88A,SHANK2,ZNF334,EFHD1,TET1,SMARCE1,SNAP25,MBD5,ANKFN1,KDM4B,SOX2,SOX5,BDP1,SOX11,SP4,SPP1,ZC3H13,RBM26,POGZ,INKA2,ZSCAN29,SEPT3,ACSBG1,SYT11,SYNE2,VPS13A,DNAJC9,TMEM150C,SYP,ANKRD28,TAF9,WSCD1,ZEB1,TCF12,CLASP1,NSD1,PUM2,DICER1,SIRT1,C18orf54,ITGB3BP,AKTIP,RELL2,TMPO,BEX4,R3HDM1,PIK3R5,TP53BP1,TPM3,C9orf85,TPM4,PDSS1,STXBP4,TRPS1,CA14,USP1,NSD2,WNT7A,XPO1,ZNF711,ZNF23,KCNT2,ZFP41,LYPD6,ZBTB16,REEP1,ZNF184,ANKS1B,SPIRE1,SMARCAD1,EMSY,LRP8,EVI5,TUBA1A,FIP1L1,WNK3,FZD3,MRPL47,IFT88,NETO2,AP3B2,ST8SIA2" Coexpression Atlas PCBC_ECTO_blastocyst_500 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500 PCBC 1.45E-11 7.39E-08 1.65E-10 1.51E-09 139 490 "KCNH8,AXIN2,ADORA1,LGR5,ASCL1,RASL11B,ASTN1,KIF1A,BMP7,CA4,CAMK2A,CCK,CDH8,CDH18,LGI1,NOG,IGLON5,CNTFR,COL9A1,COL9A2,COL9A3,COL11A2,GAL3ST1,NRG2,IGDCC3,HAPLN1,LRRC3B,CNTNAP2,PLCXD3,BOC,RIMS3,DGKG,LYPD1,SNAP91,CDON,DPP6,EFNA2,ELAVL2,EMX2,ADGRV1,CLVS1,FABP7,TMEM132C,ZIC4,SPSB4,ATP13A4,B3GAT1,PHYHIPL,CHL1,ILDR2,GLDC,GPM6A,LPAR4,GRIA4,CELF3,UBE2QL1,IGSF21,IGFBPL1,SHISA6,CELF5,PLD5,HES5,LIX1,INSM1,ZNF385B,KCNA1,OLFM3,KIF5C,LRRC4B,LMO1,CLEC18A,MAP6,BCO1,SCG3,TCEAL5,NELL1,NELL2,NHLH1,NNAT,NPY,NTRK3,IGSF11,KCNK10,CNTN3,PAX6,PRTG,ENPP2,HMGCLL1,SDK2,NECAB2,POU3F2,NKAIN4,RELN,LAMA1,PTPRD,FEZF2,RFX4,RLBP1,ZFHX4,HUNK,KCNIP1,FAM182A,LRFN5,SLC30A10,TMEM200C,SCG5,ARX,SLC1A6,RIMS1,SOX3,SOX10,SOX15,NMNAT2,CLSTN2,COLGALT2,STOX1,SST,ZFR2,TAC1,UNC5D,CNTN2,RIMBP2,CA14,TMEFF2,CLEC2L,VGF,ZIC1,ZIC2,ZIC3,KCNT2,EMX2OS,CRB2,DPYSL5,LAMP5,CADM2,STMN4,GAL3ST3,DOCK8,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb_Overall_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 1.45E-11 7.39E-08 1.65E-10 1.51E-09 23 33 "APLP1,THSD7A,INA,DCC,EBF1,SEZ6L2,ELAVL3,NRN1,GAP43,GNG3,STMN2,IGFBPL1,KIF5C,MAP6,SCG3,TAGLN3,NCAM1,NEFM,RTN1,SYT4,TAC1,CNTN2,SLC17A6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.59E-11 8.12E-08 1.81E-10 1.65E-09 212 838 "ABR,EMILIN3,ADD3,USP31,AP2A2,HECW2,C1QTNF1,ADGRF5,ALCAM,BCAR3,TRMT9B,AMPD3,LRCH2,APAF1,USP37,ARRB1,RNF182,ADGRB2,ADGRB3,BCHE,NRP2,SGCE,MYRF,LDLRAD4,CANX,ISPD,RUNX1T1,NEURL1,CDH2,CDH10,MAGI1,CDO1,RCBTB2,ZBED5,SLIT2,NRXN3,NMT2,AKAP5,ZNF521,NSL1,FAM171B,CREM,CRHBP,HAPLN1,ANKRD44,TENM4,FEZ2,VCAN,PLXNA4,EDRF1,TM9SF4,BRINP1,ARMCX4,TIAM2,BLOC1S6,DDX46,RHOBTB1,NTM,AK5,DNM2,FARSB,GOLT1B,E2F6,EDIL3,WDPCP,SEMA3D,TMTC1,FRY,ASB3,ELAVL4,ELN,EML1,STARD3NL,EPB41L2,EPHB1,ETV1,MRVI1,TMEM132C,CORO2B,MEX3B,CAP2,FOXF2,FLT1,SGIP1,SMC2,SPECC1,KHDRBS3,PNMA2,TVP23A,DKK3,MEGF10,GAB1,GABRA3,GABRA4,CHL1,GABRB1,GABRB3,JPH4,NEK6,ERAP1,PCDH17,LYVE1,PCDH11X,LOXL3,GPT2,GPM6B,FUT10,B4GALNT4,GPR37,RAPGEF4,STMN2,PARD3B,GRIN2C,BVES,GUCY1A1,RASSF8,ARHGAP19,HLF,ZDHHC15,NEGR1,IRF8,IFI16,ITGAV,KCNK2,KIT,LIFR,IL17D,MEIS2,SAMD5,RSPO2,MXI1,MYO6,HNRNPM,NAP1L2,NASP,NDP,NFIA,HCN1,DDR2,OPA1,PCDH8,PDE1A,PDE4B,GPR85,PFKFB3,PCDH18,PMP22,LRP12,MAGEL2,CEP41,PRKCB,GRAMD1C,LRRC49,GON4L,PTPRB,RGS4,TTLL7,ZFHX4,C12orf49,LRFN5,ELMOD1,ASRGL1,TRA2B,DOCK10,ZNF365,SLC1A6,SEPHS1,SLC14A1,SPHKAP,LIMCH1,SNCA,CMTR2,UNC5B,PEG10,NPAS3,SPART,C11orf87,CLASP2,THSD1,EPB41L3,ZC4H2,NEK4,COBL,DNMBP,ANO4,PCDHB15,PCDHB7,HIF3A,ZFPM2,ITGB3BP,HHIP,THBS4,ASXL3,TLR4,HEY2,TMPO,TNNT1,RBFOX2,TPM1,SYNPO2,TRO,TMEFF2,RPRM,MICAL1,PLPPR5,INTS3,STOX2,GOPC,FAM13C,ACTR3B,MSRB3,NETO1" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 2.00E-11 1.02E-07 2.28E-10 2.08E-09 189 728 "ABHD6,EMILIN3,RTL9,SEMA6A,SRPX,MARCH4,APBB2,CACHD1,CDK10,IGDCC4,SPTBN4,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDH18,CDO1,CRLF1,DIS3L,CLTB,PCYT1B,COL9A2,COL9A3,ABI3BP,MFSD4A,ENTPD4,ANKRD44,CLIP3,SNCAIP,SUSD5,ATRNL1,PYGO1,BOC,DGKG,C8orf34,GSDME,CCDC3,GRIN3A,DNM1,USP3,ACOT8,ABCC9,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,DENND4A,ETV1,HSPA12B,FCGRT,FDFT1,TESK2,BAIAP2,SCARA3,HPCAL4,SGIP1,SYT3,NBEA,ZBED3,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,TRAF3IP2,JPH4,ZNF274,GHDC,HIGD1B,CPLX2,NEU3,GFRA2,ZNF276,RAB30,RAPGEF4,GRIK4,GUCY1A1,WIF1,BACH2,HLF,HPSE2,SYNPO,AGBL5,ICA1,IDH3B,IGF1,IL11RA,JAK2,KHK,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,MATN2,SRSF12,CD200,CPNE9,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE1A,PDE3A,PDE4D,PIRT,PENK,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,ACSS3,IQSEC3,FAT4,RAP1GAP,BEND5,ZFHX4,MYH14,MRAP2,TMEM100,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,ELMO2,SMARCC2,IFT122,PDZRN3,DOP1A,TNIK,ZHX3,ARHGAP26,CDK19,EPB41L3,NKAIN2,ARHGEF9,ADAMTS17,TACR1,ANKRD12,ADGRL3,TBX15,EHBP1,TCF4,SATB2,SYNE1,PHF24,CRTC1,HIF3A,LEFTY2,ASXL3,DAAM2,PIK3R5,SYNPO2,STXBP4,TRPS1,RFTN2,TSPAN11,ZNF708,ZNF32,PMEPA1,NAV3,CERS6,ADAMTS10,SSPN,KLHDC1" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500 facebase_RNAseq_e10.5_OlfacPit_2500 Gudmap RNAseq 2.11E-11 1.08E-07 2.39E-10 2.18E-09 333 1453 "DPF1,TTYH1,SYN3,ACHE,NCKAP5,KDM5D,FMNL2,DSCAML1,TMCC3,ADD2,PLEKHH1,GRAMD1B,KIAA1211,MTUS1,KLHL13,PCDH19,KIAA1324,OSBPL6,BCAR3,DOC2A,TRMT9B,AMPD3,AMPH,ANK3,FGD2,CNIH2,APBB1,APC,EPB41L5,APLP1,DGKZ,PHYHD1,APOC1,SHTN1,LGR5,ARHGDIG,CADPS,CADM3,NOL4,KIF1A,RGS11,RGS9,BCL7A,NRP2,BLM,ZNF599,PROM1,BMP7,BMPR1B,WASF1,CACNB2,HAP1,PTBP2,BRSK2,HIP1R,MAP7,SHISA7,USP2,MTMR7,CBFA2T2,CDH2,ADGRG1,CBARP,CHGB,CHN2,SLIT2,NRXN3,KIAA1549L,NRXN1,MYL6B,TMEM59L,FAM189A2,CNTFR,AKAP7,IQCK,LETMD1,SLC4A7,SLC4A8,BAG4,MYRIP,IGDCC3,NECTIN3,ZNF385A,CRMP1,GDA,ABCG1,CRYM,LRIG1,MICAL2,IPCEF1,PLCH2,FAM169A,UBXN2A,CTNND2,KATNAL2,KIAA0586,TMEM170A,DNAJC6,SNAP91,USP3,SLC29A4,CDON,DTNA,DUSP9,E2F5,SEZ6L2,FSD1L,EFNA2,EFNA3,EGFR,ELAVL2,ELAVL4,EMX2,EPB41,DMTN,EPHB1,KCNMB2,ANKRD13B,SLC43A2,ETV1,CEND1,EXTL2,ADGRV1,EYA1,NRN1,REEP2,TUBB4A,ATP8A1,CEP78,FDFT1,MED12L,OLFM1,SPSB4,FGF12,AMOTL2,IQCG,NOP56,SYT3,DPYSL4,SMC2,HVCN1,TPK1,KHDRBS3,FUT9,TPPP3,PHYHIPL,STARD10,GATM,GCNT2,PCDH17,GGT7,RUNDC3A,GLDC,DBF4,GLI2,GLRB,TOX3,KCNMB4,GNAO1,GNG3,LNX1,GPD2,GPM6A,GPM6B,CCDC184,B4GALNT4,CECR2,STMN2,GRIK2,RNF165,MFSD2A,PSIP1,FAM107A,FAM222A,CELF3,TOX2,FRMD5,FRMD3,HSF2,HSP90AA1,SHISAL1,TUBB2B,ITIH2,KCNK1,KIF5C,KIT,LMO1,LMO2,MAOB,MAP2,MAP6,MAPT,AQP11,MBP,SHC3,MEIS1,KCTD6,SAMD5,MSI1,TAGLN3,MXI1,MYBPC1,MYCN,NASP,NCF2,RCOR2,NEFM,NNAT,VWA2,NOVA2,NRCAM,KSR2,ODF2,PAK3,PBX1,CDK18,PDE1C,PDE1B,SERPINI1,SNX10,RETREG1,SLC25A23,PLXNB1,POLR2F,FSD1,PPP1R1A,NKAIN4,RASGEF1B,MAPK4,GDPD1,SLC22A23,ELOVL2,SPDL1,ZIK1,EML5,NKAIN1,CEP97,CCDC40,SUSD4,ROGDI,RBBP8,ZMAT4,FIGN,RGS4,NUDT11,KLHDC8A,RAVER2,RPL15,RIMKLA,LGR4,HUNK,RTN1,CCDC112,SALL1,MAPK12,SATB1,LRRTM4,HES6,ZFP2,TRIM46,HSPA4L,SCG5,SH3BGR,KIF21A,FERMT1,ST6GAL1,CCDC92,CLSTN1,CXXC4,RIMS1,SNAP25,SCN3B,SOX2,KIF21B,SOX11,SP4,BEX1,RAP1GAP2,CLSTN2,SST,INKA2,KANK1,SYT11,FGD4,SYP,SYT5,MTCL1,MCF2L,WWC1,WSCD1,CUX2,ITGB3BP,AKTIP,GALNT17,HEY1,BEX4,TNNT1,TPD52,RGMB,PRMT8,TRPC1,TRPS1,CA14,HSPBP1,TST,TMEFF2,CADM1,RPRM,AMOT,UCHL1,SLAIN1,FAM181B,USP1,MEAF6,ZFP41,NDRG4,SLC26A10,LYPD6,ZNF184,DPYSL5,SMARCAD1,MEIS3,SHD,SLC38A1,TUBA1A,ADAMTS9,NAV2,PCBP4,WNK2,AMN1,FZD3,PHTF2,AP3B2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500 FaceBase_RNAseq 2.19E-11 1.12E-07 2.47E-10 2.25E-09 138 488 "EMILIN3,NDRG2,ADCY2,CCDC85A,SEMA6A,ALCAM,ARHGAP20,PCDH10,LTBP4,GPRASP2,APLP1,VAT1L,LGR5,CDK10,ASTN1,ADGRB2,ADGRB3,C1QC,CACNA1G,LDLRAD4,CACNA2D1,CBLN1,REPS2,KCNAB3,CDO1,CRLF1,KIAA1549L,PCYT1B,COX4I1,CREB5,ANKRD44,CSF1R,FEZ1,CTNND2,TOX,B3GAT3,RUSC2,NTM,CCDC3,KBTBD11,EBF1,EDNRB,SEMA3D,EGFR,ELN,EMX2,ENO2,LRRC17,EPHA5,ADGRV1,TUBB3,TUBB4A,ATP8A1,FCGRT,FGF11,TRIM16,NSG1,FYB1,DKK3,JPH4,TMEM8B,PCDH17,PPARGC1A,NTNG2,ZNF276,GLDC,PCDH11X,MAP7D2,TDRKH,NR3C1,GSN,RASSF8,TOX2,HLF,HPSE2,SYNPO,IL11RA,LRRC4B,SRSF12,CD200,COMMD5,CCDC80,THYN1,NCAM2,NEFM,NELL2,NFIA,NFIX,CNTN3,PAX6,PCDH9,PDE4D,PENK,SEMA5B,ZFYVE21,PLCL1,PLTP,TRHDE,POU3F4,FSD1,POU6F1,IRX1,PRODH,ACSS3,ZMAT4,RGS10,RPL38,RTN1,ATXN1,FERMT1,DOCK10,NTNG1,SMARCD3,SOX2,MAPK8IP3,ZFR2,ADGRL3,WSCD1,PHF24,FAM189A1,TNNT1,KCNE5,TST,UCHL1,SLAIN1,PLPPR2,TSPAN11,ZIC1,ZIC2,FMN2,TMEM237,DPYSL5,PMEPA1,CADM2,PCDH15,WNK2,KLHDC1,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.25E-11 1.15E-07 2.54E-10 2.32E-09 125 429 "SORCS1,HECW2,PCDH10,SYT13,LCORL,VAT1L,CADPS,ASPH,ASTN1,INSYN2B,RNF182,ADAM23,CDK5R1,DST,RUNX1T1,CBLN1,DCLK1,CDO1,CLGN,CRLF1,SYNPR,RAB3C,CNR1,ZNF521,ANKRD44,NCOR1,CRYM,ERC2,PYGO1,TOX,SCRN1,PITPNC1,JAKMIP2,TIAM2,MAGI2,SPOCK3,NTM,DLX1,EDNRA,EGFR,TENM1,EPHA5,EYA1,TMEM132C,SCML2,TESK2,FOXF2,SGIP1,NBEA,DACH2,MEGF10,GABRA4,GABRB1,DNER,PPARGC1A,GLRB,TOX3,GNG4,ADGRA3,LPAR4,GRIA2,WIF1,IFI16,KCNA4,LSAMP,RSPO2,MYH3,NAP1L2,NDP,DDR2,PCDH8,PDE4D,ENPP2,GPR85,NLGN3,TRHDE,LRP12,PRRX1,ING3,EPB41L4B,SLC22A23,PTPRE,TMEM255A,GAL3ST4,FIGN,ZFHX4,C12orf49,ROBO1,PRR5L,SALL1,SATB1,CSRNP3,SCN3A,FAM19A1,TNFRSF19,ANKRD6,ZNF365,SLC14A1,SLC15A2,LIMCH1,RIMS1,SON,SOX2,SOX11,TROVE2,TTBK2,KLHL7,TAC1,CAMTA1,UNC5D,ADGRL3,TBX15,TCF4,PCDHB15,PCDHB10,PCDHB3,SYNPO2,UGT8,WIPF1,PCDH20,FMN2,KCNAB1,FAM13C,CBLN2,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 200 GSE76381_ESMoleculeCountsPMLog2 2.61E-11 1.33E-07 2.94E-10 2.68E-09 236 961 "TTYH1,AXIN2,RNF150,SLC44A5,ZNF608,NME5,SORCS2,C1QTNF3,SPARCL1,C6orf89,CCDC146,APLP1,CACHD1,APP,TMEM263,RASL11B,CCDC181,ATP1A2,SGCE,LDLRAD4,CALB1,MAP7,PRC1,ARHGEF25,CBLN1,CDC25B,CDH2,CDH18,CDO1,CDR1,ADGRG1,CHN2,CLU,COL4A5,COL9A1,COL9A2,ZNF521,CP,SLC35F1,CRMP1,LRRC3B,VCAN,CNTNAP2,KIAA0408,BOC,DCAF8,PABPC5,MYEF2,DPYSL2,RCAN1,SEZ6L2,EDNRB,EFNB3,MBNL2,ING4,ELAVL3,ENO2,ERBB2,EXTL2,ADGRV1,NRN1,F3,ABCA8,TMEM132C,ZIC4,TUBB3,ZMYND10,TMEM164,C1orf61,CAP2,PCYOX1,IQCG,NBEA,TMEM107,UFM1,PDLIM5,ERGIC3,TPPP3,SALL3,GAP43,DNER,NTNG2,LOXL3,GOLGB1,GPM6B,STMN2,GRM8,GSN,FAM107A,ADAMTS6,ATOH8,WIF1,IGFBPL1,CFAP126,IGF1,DOCK7,LIX1,IL11RA,TUBB2B,ITGAV,ITPKB,OLFM3,KCND2,KCNK1,KCNQ2,KCNQ3,KIF5C,KIT,LAMA2,LAMP2,LIFR,PACRG,MBNL1,LRP1B,KCTD6,AFDN,CCDC80,TAGLN3,RSPO2,SLCO1C1,NFIA,NFE2L2,NNAT,SMIM11A,NTRK2,NUCB1,NUCB2,CNTN3,PAX6,PCDH9,PCMT1,PDE1A,PDE3A,PDE4B,PDE4D,ENPP2,PDPK1,PFKP,PKM,KCTD15,PLP1,PCDH18,PLTP,PURG,PRRX1,SDK2,NECAB2,SLC36A4,POU3F2,NKAIN4,MAPK10,HYDIN,MASP1,GDPD2,PTN,TMEM231,TMEM255A,USP47,FAT4,ZMAT4,RFX3,RFX4,MRPS18A,ZFHX4,KIRREL1,RPE65,NEK11,LGR4,WLS,S100B,DRAXIN,SCN3A,HES6,GALNT10,STUM,KIF27,PUF60,SH3BP2,KANSL3,SEPHS1,SLC8A1,ZNF334,PALLD,SOX2,SOX11,KDM3A,ENKUR,PEG10,BEX1,CDK19,RBM26,NPAS3,ZNF621,SULF2,SYNE2,PDLIM2,CNTN2,ADGRL3,AGTPBP1,ANO4,VWA3A,ZEB1,TCF12,AHCYL2,CCDC173,TEX15,DNAH7,AKTIP,HEY1,SEZ6L,TPM1,ZNF384,TRH,CA14,UBE2H,SLAIN1,FAM181B,ZIC1,ZIC2,ZIC3,ZNF711,CFAP52,ATP6V0E2,TCEAL7,FSTL5,PMEPA1,MFF,PRDM2,DNALI1,SLC38A1,ADAMTS9,WIPF2,FAM13C,NHSL1,SSPN,SPATA13" Coexpression Atlas GSM605853_500 "Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3" "Immgen.org, GSE15907" 2.66E-11 1.36E-07 2.99E-10 2.73E-09 119 403 "FMNL2,TMCC3,ADRB2,SEMA6A,ABCD2,FGD2,APP,ASPA,ATP6V0A1,ADAM23,DST,C1QC,HAP1,CAMK2D,CD86,SCARB1,CD38,DGKI,CD81,LARGE1,MS4A7,ZFYVE9,LY86,CSF1R,CSF3R,SDC3,CTNND1,CYBB,DOCK4,HDAC9,ARHGAP32,KIAA0513,RIMS3,SIRPA,ZEB2,GSDME,DLG2,DMPK,HS3ST2,ABCC5,PCOLCE2,SLC43A2,IGSF6,TLR7,SIRPB1,RPS6KC1,DLC1,ATP8A1,FCGR1A,FCGR3A,FCGRT,FER,FGR,PCYOX1,SGIP1,TMEM107,MPP6,GALC,GATM,GFRA2,HPGDS,GLUL,ATG4C,IGF1,LRRC25,DOCK7,KCNA2,KCNJ10,KCNJ16,TTYH2,SCAMP5,MITF,ADAM22,MYO9A,P2RY13,CLEC9A,ENPP2,CDK14,PLCL1,PILRA,DRAM2,RASGEF1B,GDPD1,SLC22A23,PTK2,RAB3IL1,PID1,ACER3,RXRA,SEMA6D,ATXN1,ITSN1,PPP1R9A,SLC1A3,SLC8A1,CCDC88A,SLC11A1,SLC12A2,EPB41L3,RGL1,FGD4,SYNE2,SLC37A2,ADGRL3,DMXL2,TCF7L2,TPCN2,PSD3,ARHGEF12,ATP13A2,TF,DDHD1,TLR4,TNS1,TRPM2,CADM1,VAV2,AGMO,PLD4" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k5_500 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.69E-11 1.37E-07 3.01E-10 2.75E-09 28 47 "APLP1,INA,CRMP1,GSDME,ELAVL4,FABP7,TUBB3,DPYSL4,DLL3,GAP43,LPAR4,STMN2,INSM1,TUBB2B,MAPT,TAGLN3,NEFM,GNG2,RFX4,LINC00461,SCG5,SOX2,SYT11,TRIM2,ZIC1,ZIC3,PCBP4,VANGL2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k3 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.77E-11 1.41E-07 3.09E-10 2.82E-09 91 281 "PNMA8B,PCDH10,PKP4,ATP2B1,DOCK11,BACH1,SGCE,RUNX1T1,LDB2,ZNF445,SRSF11,SLIT2,COL4A5,CSF1R,TCAF1,AIF1L,GIT2,ZEB2,ZC3H11A,CDON,SEMA3D,APH1A,EIF4G1,EPB41L2,SRRM1,TMEM132C,SEMA6C,ANKFY1,SMC2,APOPT1,SRCAP,GGTA1P,LPAR4,GRIK1,GRM7,CIT,KAT7,RASSF8,HAS2,KLF12,MIER3,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,NASP,NTRK2,OCRL,PCDH9,PIK3R1,PLCL1,PLEC,PRRX1,KANSL1,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,MEG3,ATXN2,TRA2B,CHD9,TET1,ARFGAP1,ZKSCAN3,ZC3H13,KIF1B,TROVE2,PRRC2C,SYNE2,KLHL4,TCF7L2,HIF3A,CBX5,R3HDM1,TRPS1,SSBP2,UBE3A,FLRT2,PCDH20,NAV2,SNX27,FIP1L1,JMJD1C,GAN,SENP7" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_100 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_100 FaceBase_ST1 2.89E-11 1.47E-07 3.22E-10 2.93E-09 35 68 "TTYH1,ASCL1,TTC9B,FGF17,NOG,JAM2,LHX2,FEZ1,SCRN1,DLX1,OLIG1,ELAVL3,RGS17,FABP7,FOXG1,TPPP3,RUNDC3A,UBE2QL1,IGFBPL1,HES5,LMO1,MT3,LYRM9,NFIA,SLC10A4,GDAP1L1,NKAIN4,LINC00461,SLC4A3,SOX2,NPAS3,NACAD,APOM,TAC3,SHD" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.94E-11 2.01E-07 4.39E-10 4.00E-09 102 330 "USP31,TAOK1,OGT,APAF1,APC,PHYHD1,TMEM263,ATP2B1,BARD1,BCHE,NRP2,CACNA2D1,CANX,SRSF11,SOCS6,FAM171B,VCAN,DZIP3,TM9SF4,MYEF2,ARNT2,PDCD6IP,DYRK1A,EDNRB,HIPK3,CALCRL,ETV1,DLC1,KIAA1109,SUCO,SMC2,PDLIM5,CELF1,OGA,GABRA3,AHCYL1,IQGAP2,GFRA1,PCDH17,GHR,PCDH11X,GRIA2,RASSF8,KLF12,BACH2,ZDHHC15,RBPJ,LIFR,HECTD2,MAP2,MARK1,CHIC1,KITLG,MKLN1,MMP16,SAMD5,NCAM2,NEK1,NFIA,PAK3,PDE3A,TMOD2,PIK3C2A,PRRX1,FAT3,KANSL1,MAPK8,PTPRG,REV3L,KLHL11,SETD5,RPE,TRA2B,ST8SIA1,RUFY2,NAPB,SOX5,MYCBP2,PEG10,KIF1B,CLASP2,EPB41L3,LARP4,PJA1,CAMSAP2,ADGRL3,AGTPBP1,FBXW11,TBL1X,CLASP1,NSD1,HHIP,ASXL3,ERCC6L2,RBFOX2,RGMB,TRPS1,TTC3,UBE3A,WRN,LMAN2L,NETO1" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.95E-11 2.02E-07 4.39E-10 4.00E-09 112 374 "KLHL13,NR0B1,ALCAM,ARHGAP20,LTBP4,AMH,PPP4R4,DDX3Y,TMEM108,CACNA1G,MYRF,CACNA2D1,RUNX1T1,CBLN1,CLU,CNTFR,AKAP5,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,VCAN,PLXNA4,RIPOR2,ARMCX2,DCT,ZEB2,SV2A,DNM1,EDNRA,HEYL,SEMA3D,EGFR,MRO,PLXNC1,EMX2,LRRC17,EYA1,FAM198B,FABP7,PTK2B,DLC1,FGF13,FLNC,AFF2,GABRA4,TRAF3IP2,SEPT9,GATM,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,GRIA4,GUCY1A1,KLF12,HPSE2,KCND2,KLHL23,MAP2,MATN2,NCAM1,NFIA,NME4,PAK3,PCDH9,PDE1A,PDGFRA,SERPINE2,PCDH18,PLTP,FAT3,SH3KBP1,LRRN3,RASGEF1B,LAMA1,PTCH1,PTN,TMEM255A,ZCWPW1,REV3L,ROBO1,ROBO2,ARMH4,ACER3,LGR4,MEG3,SOX6,DOCK10,PKNOX2,SORCS3,PALLD,TNIK,SMOC1,ST5,SULF2,ADGRL3,OBSL1,ZFPM2,TGFBR3,HHIP,THRA,TPM1,PLEKHH2,VSNL1,STOX2,WNK3,ST8SIA2" Coexpression Atlas Arv_EB-LF_1000 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000 PCBC 4.01E-11 2.05E-07 4.45E-10 4.06E-09 241 990 "SERPINA3,CSMD2,ELFN2,CCDC85A,TMCC3,ERMN,BEND6,NLGN4X,PCDH19,AGT,KCTD16,SORCS2,SYT13,PDZD4,DPP10,LRCH2,CNIH2,LRRC4C,LGR5,INSYN2B,RNF182,C1QC,MYRF,CALB2,CABP7,CAMK2A,VSTM2A,LGI1,SYNPR,LHX2,IGLON5,COL9A1,AKAP5,TCEAL2,IGDCC3,HAPLN1,TENM4,CSF1R,CSF3R,LRRC3B,ATRNL1,NCAN,RIMS4,PHACTR3,CNTNAP2,CYBB,DCT,LYPD1,SNAP91,SPOCK3,DLX1,FAM57B,DPP6,USH1C,EDIL3,EDN3,SEMA3D,LINC00599,ELAVL3,ELAVL4,EN2,LRRC17,SEZ6,EPHA5,ADGRV1,CLVS1,FABP7,TMEM132C,ZIC4,FCGR3A,ACTL6B,HPCAL4,C1orf61,PSD2,NSG2,DACH2,B3GAT1,TMEM151A,PHYHIPL,MEGF10,GABRA2,GABRA3,CHL1,GALNT15,ILDR2,GAD2,ARPP21,IP6K3,GAP43,SRRM4,CPLX2,DNER,GFAP,GFRA2,FREM1,CSDC2,PCSK1N,GPM6A,CCDC184,STMN2,GRIA1,GRIA2,C1QL4,GRIA4,GUCY1A1,CELF3,WIF1,UBE2QL1,NXPH2,BACH2,VSIG4,SCRG1,HPSE2,IGFBPL1,SHISA6,CELF5,BTBD17,C2orf72,IGF1,KIAA1755,PLD5,LIX1,SCRT2,BRINP3,SLC6A17,INSM1,OLFM3,CDH20,KCNMA1,KCNQ2,KIF5C,LRRC4B,C2orf80,CLEC18A,MAPT,CCDC80,SCG3,RSPO2,MYL3,LAYN,TCEAL5,NELL1,NNAT,NPY,NTRK2,OLR1,OXTR,PAX6,PCDH8,PDGFRA,PENK,CYTL1,GDAP1L1,HMGCLL1,PDZRN4,TRHDE,PRRX1,SDK2,NECAB2,MAGEL2,FAT3,POU3F2,NKAIN4,SMIM10L2B,PRPH,RELN,KLK6,PSD,LAMA1,PTHLH,PTH1R,ELOVL2,PTPRN,PTPRO,TMEM255A,RFX4,RGS4,ZFHX4,SYNDIG1,HUNK,KCNIP1,RTN1,AMER2,LRFN5,LINC00461,TNFRSF19,TMEM200C,HKDC1,PKNOX2,LRRC55,TRIM67,SLC11A1,TMEM132D,SLIT1,SLN,DMRTC1,SNAP25,ENKUR,SPP1,CLSTN2,SST,MLC1,SYT4,SYT5,TAC1,TAC3,CNTN2,ANO4,PCDHGC5,PCDHGB6,PCDHGA3,TMEM151B,TF,CRB1,SPX,ASXL3,RIMBP2,SEZ6L,DOK6,SYNPO2,FAM181B,LINC00511,ZIC1,KCNT2,FMN2,PLPP4,CRB2,REEP1,DPYSL5,CA10,SHD,STMN4,SCG2,GAL3ST3,SLC17A6,DNAH10,FAM13C,PAK5,TMEM63C,SLC4A10,JPH3" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K1 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 4.48E-11 2.28E-07 4.95E-10 4.51E-09 36 72 "ERMN,PLEKHH1,EPB41L5,PROM1,MAP7,LHX2,IGDCC3,FAM169A,ELAVL2,ELAVL4,EMX2,EPB41,RRAGB,ACSL4,KHDRBS3,FUT9,PHYHIPL,ILDR2,KIAA1841,GLDC,TOX3,PCLO,SOX21,KTN1,PAX6,NECAB2,ELOVL2,EML5,RFX4,MAPK12,KIF21A,SOX2,SP4,WWC1,WSCD1,NR2E1" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.49E-11 2.29E-07 4.95E-10 4.51E-09 121 415 "EMILIN3,ADORA1,ADGRF5,EPB41L5,ARRB1,CA4,CA8,CA12,CACNA2D1,CALB1,THSD7A,ISPD,CD86,CD38,CHN2,MS4A7,LY86,CNTN1,COL9A1,SNCAIP,CSF1R,CX3CR1,CYBB,AIF1L,CCDC3,DNM2,EMX2,EPHB1,NCALD,IGSF6,CDHR1,SIRPB1,EYA1,MRVI1,F8,FCGR1A,ST3GAL6,SGIP1,DACH2,PNMA2,FYB1,DKK3,MEGF10,GABRA4,ILDR2,IGSF5,GFRA2,FREM1,GGTA1P,LYVE1,RAB40B,GRM3,GRM7,NCKAP1L,NEGR1,IFI16,KCNA1,KCNC2,KCND3,LIG4,CLEC18A,MAPT,SYT9,TM6SF1,MSR1,MYO6,NCAM1,NCF2,NELL1,CLDN11,OXTR,PRTG,PENK,RETREG1,SCHIP1,PTPRB,PTPRO,PTX3,FAM184A,GAL3ST4,DUSP15,TTLL7,LGI2,PRR5L,RYR3,SALL1,SCN7A,SCN8A,SGK1,SH3BGR,ST8SIA1,ANKRD6,SLA,CMTR2,DDN,CLSTN2,NEK4,PLCB1,TMEM150C,ANKRD28,ANO4,ACSL6,VWC2,SATB2,PCDHB9,ARHGAP9,TEK,TF,HHIP,HEY1,TLR4,ZFP91,NPL,RGMB,SYNPO2,TRPC3,FLRT2,TMEM178A,FAM13C,CERS6,SOCS4" Coexpression Atlas PCBC_ratio_SC_vs_DE_cfr-2X-p05 Pluripotent Stem Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 4.49E-11 2.29E-07 4.95E-10 4.51E-09 121 415 "TTYH1,TMEM132B,RNF157,NLGN4X,VAT1L,ATP1A2,ATP1A3,ADAM15,PROM1,SYT6,CLDN10,AIFM1,LARGE1,CDO1,UBE2L6,CLU,TJP2,PCYT1B,TCEAL2,CRYM,VCAN,RIMS4,FAM131B,ECE2,TOX,BRINP1,JAKMIP2,ALKBH8,SACS,RABGAP1L,CHRDL1,FAM57B,DPYSL2,CACNG7,AASS,LINC00599,ANKRD13B,PIPOX,FABP7,ACSL4,PPP1R1B,ZNF589,OLFM1,FGFR1,FHL1,SEMA4D,FLT1,TACC2,NSG1,MEGF10,JPH4,IQGAP2,GCNT2,RND1,GLDC,GLI2,GNG4,GPM6B,GPR19,MFSD2A,SOX21,LINGO1,CPT1C,ATCAY,ICA1,ZIC5,IGSF1,KCNN2,KIF5A,FGFBP3,SCAMP5,MID1,MMP17,SESN3,DDX25,MYCN,MIR4697HG,NAP1L2,NAP1L3,NEFM,NELL2,NPTX2,OCRL,ZDHHC22,PBX1,CAMKV,PIK3CD,PCDH18,EPB41L4B,PPM1B,PPP2R2B,PRODH,GDPD2,PTN,PTPRZ1,NKAIN1,PRRT2,ARHGEF10L,LGR4,SCG5,SLC6A8,PDZRN3,TRERF1,SOX2,UNC5B,SEPT3,STXBP1,RHBDL3,ARHGEF9,SYT1,COBL,TAC3,PJA1,UNC5D,FBXW11,WSCD1,THBS4,RELL2,VSNL1,TCEAL7,GAL3ST3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.83E-11 2.47E-07 5.31E-10 4.84E-09 124 429 "GALNT13,SORCS1,HECW2,PCDH10,FAM135A,SYT13,LCORL,VAT1L,CADPS,INSYN2B,RNF182,ADAM23,DST,LDLRAD4,RUNX1T1,CBLN1,MYOM2,CDH2,DCLK1,CDO1,SYNPR,SLIT2,PLAA,CNR1,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,HDAC9,TOX,PITPNC1,MAGI2,SPOCK3,NTM,DLX1,EDNRA,EGFR,TENM1,EPHA5,EPS8,EYA1,TMEM132C,SCML2,UBE2E3,FOXF2,SGIP1,NBEA,DACH2,MEGF10,GABRA4,GABRB1,DNER,GLRB,TOX3,RAB40B,LPAR4,GRIA2,MAP4K5,WIF1,NEGR1,IFI16,LRRTM3,KCNA4,LSAMP,RSPO2,MYH3,NAP1L2,DDR2,PAK3,PCDH8,GPR85,NLGN3,TRHDE,PRRX1,ING3,MAPK8,ZIK1,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,PRR5L,SALL1,SATB1,CSRNP3,SCN3A,LRRTM4,FAM19A1,NTNG1,ANKRD6,ZNF365,SLC14A1,SLC15A2,LIMCH1,SON,SOX2,SOX11,NPAS3,TROVE2,ELOVL4,TTBK2,KLHL7,TAC1,UNC5D,ADGRL3,TBX15,TCF4,PCDHB15,PSD3,PCDHB3,PUM2,ZFP91,ERCC6L2,SYNPO2,SSBP2,UGT8,PCDH20,ZBTB14,PARP11,FAM13C,CBLN2,SOCS4" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K2 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.85E-11 2.48E-07 5.32E-10 4.85E-09 64 173 "SLITRK1,ASTN1,ATP2B2,MPDZ,JAZF1,HAP1,ADGRG1,LHX2,TJP2,IQCK,ST18,KATNAL2,JAKMIP2,DLX1,MAMLD1,ELAVL4,SLC43A2,FOXG1,ATP2C1,OGA,BRPF3,C15orf41,SRRM4,KIAA1841,PCDH11X,GPM6A,PCLO,GRIK2,MFSD2A,TOX2,IGFBPL1,USP51,INSM1,KIF5C,KTN1,PAXBP1,MAP2,SHC3,ADAM22,MYT1,GPR137C,PAX6,PCMT1,SSH1,ELOVL2,ENOX1,FEZF2,GAL3ST4,LINC00461,CASC3,SCG5,KIF21A,LMO3,STAU1,SYNE2,ARHGEF12,BHLHB9,NR2E1,UCHL1,ZNF23,STMN4,TMEM163,KAT6A,SENP7" Coexpression Atlas Arv_SC-hpx_blastocyst_1000_K3 AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 5.14E-11 2.62E-07 5.62E-10 5.13E-09 142 512 "SYN3,TMEM132B,ADCY2,ADCY8,NLGN4X,SEMA6A,PDZD4,RASL11B,KIF1A,HAP1,SYT6,MAP7,CLDN10,DLGAP1,CHGA,RAB3C,DLGAP3,FAM189A2,FAM19A5,SULT4A1,IGLON5,COL9A1,COL9A3,GAL3ST1,TCEAL2,HS3ST5,C1QL2,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,SEC14L5,NOS1AP,RIMS3,KCTD8,BRINP1,HS3ST4,DPP6,USH1C,AASS,LINC00599,ELAVL2,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GNG4,GPM6B,CECR2,GRIA4,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,BTBD17,ZIC5,IGSF1,TUBB2B,LRRTM3,KCND2,KCNQ2,KIF5A,KIF5C,CAMK2N2,CPNE9,JAKMIP3,SCG3,DDX25,FXYD7,RCOR2,ZDHHC22,PAH,GDAP1L1,CAMKV,PLP1,PSAT1,NECAB2,FAT3,PPP2R2B,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,RET,RIMKLA,RYR1,SALL1,TMEM200C,SCG5,SH3GL2,SLC1A6,TMEM132D,SLCO1A2,IGSF9B,SNCB,SOX2,SOX3,LHFPL4,HECW1,SEPT3,ZFR2,ARC,COBL,TAC3,UNC5D,KLHL4,ENHO,TLL2,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CADM2,XKR7,GAL3ST3,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.45E-11 2.78E-07 5.94E-10 5.42E-09 24 37 "TMCC3,PCDH10,ANK3,INA,KIAA0408,NTM,ELAVL2,ELAVL4,EN2,NSG2,NSG1,GAP43,GPM6A,STMN2,LSAMP,NCAM1,PBX1,PDZRN4,RTN1,SCN3A,MYT1L,UCHL1,CELF4,REEP1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.45E-11 2.78E-07 5.94E-10 5.42E-09 24 37 "SYT13,ANK3,SEPT7,ELAVL3,NSG2,NSG1,PNMA2,GAP43,GPM6A,STMN2,CELF3,BEX5,NCAM1,RTN1,SCN3A,SNAP25,SCN3B,PEG10,SYT4,VGF,CELF4,REEP1,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA_Subtype_hDA0_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.71E-11 2.91E-07 6.21E-10 5.66E-09 33 63 "TMCC3,AP2A2,PCDH10,ANK3,ZBTB10,INA,ADGRG1,CRHBP,KIAA0408,NTM,ELAVL2,ELAVL4,EN2,NSG2,NSG1,AP4B1,GAP43,GPM6A,STMN2,NEGR1,LSAMP,TAGLN3,NCAM1,ZDHHC22,PBX1,GPR173,PDZRN4,RTN1,SCN3A,MYT1L,UCHL1,CELF4,REEP1" Coexpression Atlas PCBC_ratio_Sex-Associated_Pluripotency-Differentiation-2X-p05 Sex-Associated_Pluripotency-Differentiation-fold2.0_adjp0.05 PCBC_AltAnalyze 6.08E-11 3.10E-07 6.60E-10 6.01E-09 155 574 "ASIC1,KDM5D,ADCY5,ADCY8,PNMA8B,ESYT2,KLHL13,PCDH19,ZNF578,PDZD4,AMH,LRCH2,CNTNAP1,APOC2,ZFYVE28,PLA2G4C,PCDHGB4,DDX3Y,FGF17,CA4,CCK,CCKBR,RGN,SYNGR3,KCNAB3,CLGN,CHGA,ABCG2,FAM19A5,ZFP28,CREB5,IPCEF1,NCAN,CALY,PYGO1,DCC,ELMO1,KIAA0319,HS3ST4,HS3ST2,SHANK1,DPP6,MAMLD1,FAM135B,PHC2,OPTN,LPAR6,RGS17,EN2,ENO2,RAB9B,CEP85L,ETV1,DUSP27,CEND1,ZNF585B,ZIC4,CORO2B,DLC1,FOXG1,C1orf61,SGIP1,DLL3,GABRA5,CHL1,GATM,ALDH1L1,ADAM28,TTBK1,DCLK2,GNG3,RAPGEF4,STMN2,GRID1,GRIK2,NR3C1,GRM8,RNF165,GSTT2,ATOH8,TMEM179,HBA1,CELF5,BTBD17,ITGAM,ZNF667-AS1,MAP6,MATK,SYT9,SHC3,WDR49,ZNF680,TAGLN3,MDGA1,ZNF862,NEFH,NFIX,NNAT,NODAL,PAK3,PCDH8,PDE1C,CYTL1,PLP1,TRHDE,NECAB2,FA2H,SH3KBP1,POU3F4,MAPK10,PTX3,RAB3A,TMEM255A,DUSP15,MORC4,RIT2,KLHDC8A,MEG3,ZNF568,LRFN5,SCN7A,NLGN4Y,BCAN,SLC1A3,TMEM132D,ZNF667,UNC80,MYT1L,SOX3,SOX5,SOX15,LMO3,SSTR2,AJAP1,SYT4,SYT5,ZNF571-AS1,ZEB1,PCDHGA6,PCDHGA4,PCDHB3,TEK,SEZ6L,RUNDC3B,ANKRD20A2,TTTY15,AMOT,OSBP2,VGF,ZIC1,EML6,LAMP5,GJC2,NLRP3,ZNF248" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.20E-11 3.16E-07 6.71E-10 6.12E-09 22 32 "ASCL1,INA,SEPT7,NRXN2,ELAVL4,EN2,FABP7,TAOK3,C1orf61,NSG2,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,NCAM1,RTN1,SCN2A,SCN3A,MYT1L,CELF4" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 6.30E-11 3.21E-07 6.81E-10 6.20E-09 146 532 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,SPTBN4,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,ZNF599,SCAPER,C1QC,GPC2,LDLRAD4,REPS2,KCNAB3,CDH18,CDO1,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,DGKG,TIAM2,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,EPB41L1,RAB9B,EPS8,ARMCX1,PTK2B,SGIP1,ZBED3,DLL3,STAU2,ABLIM2,FYB1,ZMAT1,DKK3,GAA,ARPP21,GHDC,TMEM8B,GHR,LYVE1,GNG4,GRK4,GRIA1,GRIK4,TMEM25,GUCY1B1,TCEAL6,ICA1,SCIN,IL11RA,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,CPNE9,N6AMT1,MYH3,NEXMIF,TCEAL5,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,DIRAS2,MASP1,PEX5,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,MORC4,PRIMA1,MYH14,MRAP2,STK32B,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,DOCK10,SLC1A2,SLC6A9,SMARCC2,ARHGAP26,IQSEC2,C11orf87,NKAIN2,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,CRTC1,ATP13A2,DAAM2,LRRC24,LAMP5,PMEPA1,CADM2,LRP8,PCDH15,CERS6,SSPN,DPF3,PRRT4" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.40E-11 3.26E-07 6.90E-10 6.28E-09 212 850 "RNF157,SLC12A5,FAM135A,DOC2A,AMPH,EP400,EPB41L5,VAT1L,SFMBT2,CASK,ARRB2,ZSCAN18,ASTN1,ATP1A2,ATP2B2,ADAM23,MPDZ,ZNF599,BMP7,OSGIN2,CA4,CACNA2D1,CALB1,KALRN,PTBP2,METTL6,ARHGEF2,CDH2,TBRG4,CRLF1,RCBTB2,FAM189A2,FAM19A5,MAP4K4,PCYT1B,COL9A1,ZNF521,ZFP28,NSL1,CRMP1,HAPLN1,CRYM,CSNK1E,SIPA1L1,PPP1R16B,CTH,GREB1,NRSN1,GPSM1,ECE2,KATNAL2,PHF19,SPOCK2,BRINP1,AIF1L,GIT2,GSDME,SMG7,SNAP91,TMCC2,GRIN3A,RAB39B,DUSP9,USH1C,EDN3,EEF1D,EFNA3,ELAVL4,KCNMB2,SLC43A2,SPEG,CDHR1,EYA1,CD320,ST3GAL6,SPSB4,FGFR1,SCARA3,PSD2,FLYWCH1,DPYSL4,SPECC1,HVCN1,USP21,PRELID3A,NSG2,DACH2,TVP23A,MEGF10,GABBR1,GABRA1,CHL1,DENND2A,GALC,MTHFD2,WASF3,GFRA1,FREM1,BRD8,CBX1,KCNMB4,GP1BB,B4GALNT4,STMN2,GRM3,KIF3A,FAM19A2,LINGO1,FAM107A,RNFT2,HAS2,TOX2,PADI2,INSM1,KCNK2,KIF5C,KIT,LSAMP,MEIS1,MEIS2,MID1,MSI1,JAKMIP3,PTOV1,TAGLN3,FXYD6,NELL1,NPTX1,NRCAM,NTRK2,PBX1,PCDH8,PRTG,GPR173,HMGCLL1,ANKRD16,PMS2,PRRX1,EPB41L4B,CEP41,DIRAS2,GON4L,PTX3,NKAIN1,CEP97,CCDC40,FAT4,GAL3ST4,ZMAT4,TSPY26P,FIGN,SLC25A36,C12orf49,PRR5L,RPS6KA2,HUNK,RYR1,SALL1,MAPK12,CSRNP3,DRAXIN,HES6,SLC30A10,ZNF821,ASRGL1,DOCK10,NTNG1,ANKRD6,SLC1A3,SLC4A3,DHX30,PKNOX2,SEPHS1,SLC9A5,KBTBD4,ZNF334,IFT122,KIF21B,EMC1,CAND2,C11orf87,CLSTN2,THSD1,APOM,STXBP1,SYT11,TAL1,ANO4,CUX2,AKNA,DICER1,HEY1,CBX5,ASXL3,TP53BP1,TPM2,CA14,TTPA,CADM1,NSD2,XPO1,SF1,ZNF24,ZNF142,ZBTB16,ZNF184,LRP8,PCBP4,FZD3,VANGL2,AAAS,NETO2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.82E-11 3.48E-07 7.33E-10 6.68E-09 69 194 "VAT1L,CADPS,C1QC,INA,CNTFR,CRMP1,CLIP3,FEZ1,SCRN1,EDNRA,CACNG7,ELAVL2,LRRC17,EYA1,FABP7,TUBB3,TUBB4A,EFEMP1,NSG1,GAP43,SYT17,IGSF5,GFRA1,GFRA2,FREM1,GLI2,GNAO1,GNG3,B4GALNT4,STMN2,CELF3,ACOT7,HPSE2,LIX1,L1CAM,MATN2,SCG3,TAGLN3,NEFM,NELL2,NFIX,PDGFRA,SLC10A4,PENK,GDAP1L1,FXYD1,PMP22,PRRX1,FAT3,NKAIN4,MAPK10,PRPH,MASP1,TMEM255A,RET,RTN1,FAM19A1,SCG5,SNAP25,SCN3B,SST,SULF2,SYT11,ADAMTS17,SYT1,CUX2,TMEFF2,UCHL1,STMN4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl3_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 8.31E-11 4.24E-07 8.92E-10 8.13E-09 35 70 "TTYH1,NDRG2,ADCY2,SPARCL1,ALCAM,ATP1A2,CDO1,CLU,NCAN,LYPD1,DPP6,EDNRB,EFNB3,ADGRV1,FABP7,C1orf61,TPPP3,DKK3,GPM6B,SCRG1,CFAP126,HES5,FGFBP3,NRBP2,NFIA,NTRK2,PMP2,NKAIN4,PTN,PTPRZ1,RFX4,BCAN,SLC1A3,SULF2,MLC1" Coexpression Atlas geo_heart_1000_K5 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 8.70E-11 4.44E-07 9.32E-10 8.49E-09 123 428 "TKTL1,ACTN2,ADCY5,DPY19L2P4,AGT,CARNS1,MYH7B,DDO,CPNE5,SPTBN4,ATP1A3,B3GALT2,MYOM1,RGS11,LDHD,CA4,CACNB2,DIRAS1,CAMK2A,CAMK2B,USP2,ENTPD2,MYOM2,LONRF2,MS4A7,LSMEM2,AKAP6,NRG2,CSF1R,PDE4DIP,PLCXD3,DMPK,ECM2,EEF1A2,HEYL,SRPK3,ELN,RCAN2,DUSP27,TMEM132C,FGF12,FLNC,FOLR2,SORBS1,KBTBD12,ABLIM2,IP6K3,MYOZ2,CYP46A1,GPD1,DIPK1C,GPR17,GPR22,TPPP,PLPP7,LINC01550,UBE2QL1,FRMD3,HLF,SYNPO,KCND3,KCNJ5,KCNJ11,MAOB,MAPT,COL28A1,MT3,NCAM1,NFIX,NTRK2,PDE1C,PDE3A,PGAM2,RETREG1,PLCL1,PLIN1,FXYD1,PRRX1,MAPK4,FITM2,PROX1,MASP1,DKFZp779M0652,PYGM,CRTAC1,MYH14,GLDN,SYNDIG1,RXRG,SCN2B,SCN4B,SCN7A,FHOD3,SLC4A3,SLC1A7,SMTN,LIMS2,SLC8A1,SPHKAP,IGSF9B,FAIM2,PDZD2,ADHFE1,VWC2,PCDHGC5,PCDHGA6,PCDHGA3,PCDHGA2,TF,TIMP4,TMOD1,TNS1,TPM1,SYNPO2,FNDC5,ANO5,VIPR2,ETNPPL,NDRG4,WNK2,ADAMTSL3,SSPN,DPF3" Coexpression Atlas Arv_SC-LF_1000 AravindRamakr_StemCell-LF_top-relative-expression-ranked_1000 PCBC 9.31E-11 4.75E-07 9.96E-10 9.07E-09 239 988 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,ADCY5,ADCY8,GALNT13,ADD2,UNC5A,OLMALINC,NLGN4X,SEMA6A,PDZD4,DPP10,PPP4R4,PLA2G4C,RASL11B,KIF1A,CARMIL3,AZGP1,SYT6,BRSK2,MAP7,CLDN10,SYNGR3,DLGAP1,CHGA,PLEKHB1,RAB3C,CHRNB2,DLGAP3,FAM189A2,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,CRYBB1,LRRC3B,ATRNL1,NCAN,RIMS4,CNTNAP2,ERC2,SEC14L5,KATNAL2,RIMS3,KCTD8,BRINP1,AIF1L,JAKMIP2,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,EDNRB,AASS,LINC00599,ELAVL2,RASGRP2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PRAM1,PPP1R1B,OLFM1,SPSB4,ACTL6B,C1orf61,SYT3,DACH2,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,SALL3,ATP8A2,DNER,GLDC,PCDH11X,GNG3,GNG4,GPM6A,GPM6B,GPR19,LPAR4,CECR2,GRIA4,ADAMTS8,GRM3,PTPN5,COQ10A,MFSD2A,LINGO1,RNFT2,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,TUBB2B,KCND2,KCNN1,KCNN2,KCNQ2,KIF5A,KIF5C,LRRC4B,CAMK2N2,FGFBP3,C2orf80,MATK,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,NODAL,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PLP1,MAGEL2,EPB41L4B,PACSIN1,POU3F4,PPP2R2B,NKAIN4,RAB39A,PRKCG,LAMA1,GDPD2,PTPRZ1,TMEM145,NKAIN1,FAM184A,KHDRBS2,ZMAT4,RIT2,MRAP2,SGSM1,RIMKLA,SYNDIG1,MEG3,RYR1,SALL1,SCN4B,LRRTM4,TMEM200C,SCG5,SH3GL3,SLC1A6,PREX2,SLC8A2,SEPHS1,TMEM132D,SLCO1A2,TET1,SNCB,SNRPN,SOX3,SOX15,LHFPL4,SOX21-AS1,SEPT3,ACSBG1,ZFR2,ARC,COBL,SYT4,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,SLC19A3,CCDC173,RNF175,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,PRMT8,CA14,RPRM,VGF,VIPR2,VSNL1,RBFOX3,SLC13A3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.07E-10 5.46E-07 1.14E-09 1.04E-08 28 49 "DPP10,VAT1L,BRSK2,CHGB,CNR1,CNTN1,AKAP6,MYRIP,NRSN1,ELAVL2,ELAVL4,GAP43,DNER,STMN2,GRM7,FAM19A2,INSM1,MAP4,NEFM,NTRK2,NALCN,MAPK10,PRPH,RET,RGS4,SNAP25,SCN3B,C11orf87" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_1000 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.13E-10 5.75E-07 1.20E-09 1.10E-08 213 860 "SDE2,ABAT,FMNL2,ADCY2,SLITRK1,HECW2,KLHL13,NR0B1,SPARCL1,ARHGAP20,KCNT1,CACHD1,LRRC4C,CDC14B,PPP4R4,ZSCAN18,ZBTB10,NUMB,RASL11B,TMEM108,ATP2B3,WASF1,MYRF,CACNB2,CALB1,KALRN,RUNX1T1,CBLN1,CBFA2T2,CDH10,DCLK1,CDH18,MAGI1,CHRM4,SLIT2,CNN3,CNTFR,AKAP5,ZNF521,HAPLN1,HINFP,CLIP3,TENM4,ATRNL1,VCAN,PLXNA4,BOC,DOCK4,DAPK1,BRINP1,ELMSAN1,DCT,ZEB2,TIAM2,MAGI2,POM121,SV2A,SRGAP3,EXOG,DNM1,CPEB2,DRP2,TSPAN5,EDN1,EDNRA,PLXNC1,SORBS3,C8orf37,EMX2,EPB41L1,MTSS1L,CEP85L,NRN1,F3,ABCA8,FAM198B,FABP7,TUBB4A,AMOTL2,MEX3B,EVL,FLNC,AFF2,CAMKK2,NSG1,GABRA4,GABRB1,TRAF3IP2,DENND2A,NEK6,FREM1,CSDC2,GHR,GLI2,PCDH11X,GPR37,BVES,GUCY1A2,GUCY1A1,TCEAL6,SHISA6,NKD1,TUBB2B,KCND2,KCNH1,KCNH2,KLHL23,PACRG,MAP2,MATN2,MEIS1,MEIS2,KITLG,AFF1,SESN3,CCDC80,CTNNA3,MTR,TCEAL5,NCAM1,ZC3H12B,NEFM,NFIA,NNAT,NME4,NUCB2,PDE1A,PDGFRA,GNG2,PFKFB3,SERPINI1,PIK3R1,ZNF655,PCDH18,PRRX1,SDK2,ING3,PPP2R2B,PPP3CC,RASGEF1B,PRKCB,SYTL2,LAMA1,PTN,PTPN13,PTPRG,TMEM255A,RADX,RIC8B,ROBO1,ROBO2,TMEM206,LGR4,MEG3,HUNK,KCNIP1,CLIP1,SOX6,STUM,MRAS,KIF27,RASA3,ST6GAL1,ST8SIA1,WDR37,SLC4A3,PKNOX2,SNCA,PALLD,KDM3A,UHRF1BP1L,PEG10,TSPYL2,SMOC1,ZC4H2,ST5,SULF2,KLHL7,ADGRL3,KLHL4,PSD3,OBSL1,CCDC173,TEX15,DNAH7,ZFPM2,HEY1,ACTR6,ASXL3,DAAM2,BEX4,KAT6B,TNNT1,TPM1,TRPC1,TRPS1,FNDC5,SSBP2,TMEFF2,PLEKHH2,VAV2,VSNL1,PCDH20,ZFP37,ZNF711,ZNF23,LYPD6,ZNF184,NAV2,WNK3,FRMD6,DPF3,ST8SIA2" Coexpression Atlas ratio_SC_vs_ECTO_2500_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 1.13E-10 5.78E-07 1.20E-09 1.10E-08 214 865 "DPF1,SYN3,CSMD2,GPRIN1,TMEM132B,ADCY2,SLITRK1,ADCY8,GALNT13,RNF157,ADCYAP1R1,SORCS1,UNC5A,PWWP2A,PTCHD1,NLGN4X,KLHL13,OSBPL1A,GPRASP2,PDZD4,LRFN1,PPFIA2,NT5C3B,PPFIA3,CCDC74A,CARMIL3,CALB1,SYT6,VSTM2A,CBS,CLDN10,DCLK1,CHGA,CHRNA4,RAB3C,SLC24A2,FAM189A2,FAM19A5,CCDC151,BTF3L4,HS3ST5,CRYBB1,C1QL2,LRRC3B,GALNT9,VCAN,RIMS4,SEC14L5,TOX,EARS2,KIF26A,LONRF1,KCTD8,PHYHIP,TMEM170A,BRINP1,JAKMIP2,C8orf34,DGCR5,MAGI2,ALKBH8,PARD6A,RABGAP1L,CHRDL1,RAB39B,HS3ST2,CALN1,ST8SIA3,WDPCP,CACNG7,EBI3,AASS,LINC00599,TENM1,SEZ6,ANKRD13B,MRPL10,ETV1,PIPOX,TBC1D16,TUBB4A,PPP1R1B,OLFM1,POLR1B,SPSB4,MAD2L2,HPCAL4,FLT1,NOP56,SYT3,SPECC1,CSPG5,MEGF11,MEGF10,GABRA1,HRASLS5,GABRA5,GABRB3,JPH4,ATP8A2,IGSF5,GCK,GNG4,GPM6B,GRIN1,ADAMTS8,GRIN2D,LINGO1,WIF1,IGSF21,C1orf94,HRH3,HNF4G,CPT1C,LRRC75A,ATCAY,SHISAL1,ZIC5,KNDC1,IGSF1,RIPPLY2,LRRTM3,C2CD4C,KCND2,KCNN1,KCNN2,KCNQ2,KHK,KIF5A,CAMK2N2,SFXN5,FGFBP3,ARHGAP12,C2orf80,CPNE9,JAKMIP3,SCG3,DDX25,MYCN,FXYD7,NODAL,NOS1,NPTX2,HCN1,ZDHHC22,PAH,GDAP1L1,CAMKV,JAKMIP1,SLC36A4,FAT3,POU3F4,PPP2R2B,PPP2R2C,PRODH,PTPRZ1,TMEM145,NKAIN1,SLC25A48,ZMAT4,TSPY26P,RET,RIT2,RORB,MRAP2,RIMKLA,STX1B,RYR1,BCAN,PREX2,SEPHS1,SHANK2,TMEM132D,OGDHL,IGSF9B,SNCB,SNRPN,LHFPL4,HECW1,STAC2,SEPT3,AJAP1,NECAB1,FGD4,RHBDL3,SYN1,ARC,SYN2,COBL,TAC3,TACR1,KLHL4,ACSL6,TMEM151B,CCDC173,TEX15,CHST8,ENHO,TLL2,ANKRD24,IL34,UGT8,SLAIN1,MGAT5B,VSNL1,RBFOX3,ZIC3,PLPPR5,SLC38A1,GAL3ST3,NAV2,ITM2C,NETO1,ZNF30" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.15E-10 5.86E-07 1.22E-09 1.11E-08 95 305 "ADCY2,KLHL13,OSBPL6,ALCAM,ARHGAP20,PCDH10,DPP10,CADPS,ATP2B1,ADGRB2,IL33,CACNA1D,CACNA2D1,ISPD,LDB2,CD86,DCLK1,NRXN3,LY86,CNTN1,CNRIP1,AKAP12,SNCAIP,ATRNL1,VCAN,ZFYVE16,ZEB2,NTM,PLXNC1,EPB41L2,NCALD,RASL12,MRVI1,HSPA12B,EFCAB2,DACH2,DKK3,FREM1,RAB40B,GRIA1,GRIA4,GUCY1A1,UBE2QL1,ZHX1,NEGR1,IL11RA,KCND3,LAMA2,MATN2,MMP16,CCDC80,MSR1,NCAM1,NDP,NRDC,CLDN11,PCDH9,PDE3A,GPR85,GNG2,PENK,TMOD2,TRHDE,PRRX1,NKAIN4,PTX3,PID1,RGS4,LGI2,SYNDIG1,LRFN5,SCN7A,ST8SIA1,CXXC4,PALLD,SAMSN1,PLCB1,SYT4,PJA1,PDLIM2,ANO4,VWC2,CUX2,PCDHB9,PCDHB3,THBS4,SYNPO2,TRO,TMEFF2,FLRT2,PROCA1,SPIRE1,NAV3,MSRB3,CBLN2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.25E-10 6.37E-07 1.32E-09 1.20E-08 24 38 "ANK3,RUNX1T1,INA,KIAA0408,ELAVL2,ELAVL4,EMX2,NRN1,TUBB3,NSG1,GAP43,GNG3,GPM6A,STMN2,GRIA2,KIF5C,TAGLN3,NCAM1,NEFM,NNAT,NOVA1,RTN1,SCN3A,KIF21B" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRN_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.25E-10 6.37E-07 1.32E-09 1.20E-08 24 38 "ANK3,RUNX1T1,INA,KIAA0408,ELAVL2,ELAVL4,EMX2,NRN1,TUBB3,NSG1,GAP43,GNG3,GPM6A,STMN2,GRIA2,KIF5C,TAGLN3,NCAM1,NEFM,NNAT,NOVA1,RTN1,SCN3A,KIF21B" Coexpression Atlas Arv_SC-H9hpx_2500_K5 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 1.56E-10 7.94E-07 1.64E-09 1.50E-08 239 993 "KCNH8,SYN3,CSMD2,TMEM132B,ADCY2,SLITRK1,ADCY8,GALNT13,NLGN4X,SEMA6A,UNC79,PDZD4,DPP10,RASL11B,KIF1A,CARMIL3,RGS9,GYG2,HAP1,SYT6,BRSK2,MAP7,CLDN10,SYNGR3,DLGAP1,CACNA2D2,CHGA,RAB3C,DLGAP3,SLC24A2,FAM189A2,FAM19A5,SULT4A1,IGLON5,COL9A1,COL9A3,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,C1QL2,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,FAM169A,ERC2,SEC14L5,NOS1AP,LONRF1,RIMS3,KCTD8,BRINP1,AIF1L,ARMCX4,JAKMIP2,RABGAP1L,CHRDL1,RAB39B,HS3ST4,CALN1,FAM57B,DPP6,SLC25A18,USH1C,AASS,LINC00599,ELAVL2,BSCL2,SEZ6,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SPSB4,MAD2L2,HPCAL4,C1orf61,SYT3,CSPG5,DLL3,B3GAT1,TVP23A,MEGF10,HRASLS5,GABRA5,GABRB3,JPH4,SALL3,SYT17,ATP8A2,SRRM4,TTBK1,RND1,TOX3,PCDH11X,GNG4,GPT2,GPM6B,LPAR4,CECR2,GRIA4,ADAMTS8,KAT7,SOX21,LINGO1,PSIP1,TMEM179,WIF1,IGSF21,PADI2,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,BTBD17,ZIC5,IGSF1,TUBB2B,LRRTM3,KCND2,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,SCAMP5,CPNE9,JAKMIP3,ADAM22,SCG3,DDX25,FXYD7,RCOR2,ZDHHC22,PAH,NLGN3,GDAP1L1,SEMA5B,CAMKV,PLP1,PNMA3,PSAT1,NECAB2,EPB41L4B,FA2H,FAT3,PPP2R2B,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,SLC25A48,FAM184A,ZMAT4,RET,LGI2,ZNF532,RIMKLA,RYR1,SALL1,LRRTM4,TMEM200C,SCG5,SH3GL2,PPM1E,CNKSR2,BCAN,SLC1A6,SLC8A2,SEPHS1,SHANK2,TMEM132D,SLCO1A2,OGDHL,IGSF9B,SNCB,SNRPN,SOX2,SOX3,NMNAT2,LHFPL4,HECW1,SOX21-AS1,SEPT3,AJAP1,NECAB1,FGD4,ZFR2,ARC,COBL,TAC1,TAC3,UNC5D,WWC1,CUX2,TMEM151B,FAM189A1,CCDC173,SIRT1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,KCNE5,CA14,TUBB2A,RPRM,CLEC2L,VGF,VSNL1,RBFOX3,SLC13A3,KCNK12,ZIC2,ZIC3,KCNT2,TMEM198,DPYSL5,PLPPR5,DHX33,CADM2,STOX2,XKR7,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.58E-10 8.04E-07 1.66E-09 1.51E-08 20 28 "INA,FAM171B,ZNF804A,DLG2,ELAVL2,ELAVL4,EYA1,FABP7,TUBB3,GAP43,GNAO1,KIF5C,SYTL4,SCG3,NEFM,MAPK10,EML5,SNAP25,SCN3B,CUX2" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.76E-10 8.96E-07 1.84E-09 1.68E-08 117 405 "ADD1,ADD3,PNMA8B,TAOK1,C1QTNF3,SRPX,ARHGAP20,LTBP4,LCORL,PKP4,DDX3Y,ATP1A2,ATP2B1,BACH1,SGCE,IL33,VSTM2A,RUNX1T1,DCLK1,ZNF445,SRSF11,CHM,SLIT2,NMT2,COL4A5,CP,RBM39,PLCXD3,PUM1,FGFR1OP2,RIPOR2,AIF1L,ZEB2,ZC3H11A,GSDME,CDON,ABCC9,EDNRA,EIF4G1,ELN,CALCRL,EPB41L2,LRRC17,SCML2,FGF1,ANKFY1,SMC2,GABRB1,ILDR2,GAD1,CSDC2,GLUL,CNDP1,LPAR4,PARD3B,GRM7,RASSF8,HAS2,KLF12,KCND3,MAOB,MAP4,MATN2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,NASP,NFIA,NFIX,CNOT4,PCDH9,PENK,NALCN,PIK3R1,PLTP,RC3H2,PRRX1,FAT3,MAPK8,TMEM255A,C1orf54,RNASEL,LGI2,TMLHE,MEG3,FNIP1,SFPQ,TRA2B,ARX,CHD9,TET1,ZCCHC24,ZC3H13,RBM26,PRRC2C,SYNE2,PCDHB9,OBSL1,HHIP,CBX5,R3HDM1,TNS1,TPM1,NR2C2,TRPS1,SSBP2,UBE3A,UBTF,FLRT2,VLDLR,PMEPA1,ADAMTS9,SNX27,RGS7BP,GAN" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 1.85E-10 9.45E-07 1.94E-09 1.77E-08 50 124 "PLEKHH1,EPB41L5,PROM1,MAP7,NRXN2,CNTFR,IGDCC3,FAM169A,CTNND2,RIMS2,JAKMIP2,PLXNC1,ELAVL2,LRRC23,ACSL4,FHL1,ZCCHC17,FUT9,PHYHIPL,GABRB3,ILDR2,TCERG1,GLDC,TOX3,MAP7D2,GPR19,SOX21,USP51,KIT,KTN1,SCG3,NASP,NOVA1,ODF2,FAM98B,SEMA5B,ELOVL2,EML5,CCDC40,RFX4,KIF21A,NEK4,ANKRD28,WWC1,PRMT8,SLAIN1,FLRT1,FAM181B,RBFOX3,KCNT2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K4 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.06E-10 1.05E-06 2.15E-09 1.96E-08 41 92 "NCKAP5,LTBP4,GPRASP2,ASTN1,SLC25A14,LONRF2,SRSF11,NRXN3,KIAA1549L,CNTFR,CREB5,FEZ1,ST18,TOX,SV2A,DMD,SHANK1,TMEM35A,EPHA5,CHST15,NRG3,PPARGC1A,MFSD2A,NEXMIF,NCAM2,NELL2,NFIA,PCDH9,POU6F1,MDGA2,ATXN1,NLGN1,NPAS3,CLSTN2,SEMA4A,ACSL6,AZIN2,KCNE5,FLRT1,FMN2,SENP7" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_1000 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.10E-10 1.07E-06 2.19E-09 2.00E-08 56 147 "PCDH10,SYT13,INSYN2B,CH25H,RUNX1T1,ANKRD44,TENM4,PYGO1,HDAC9,TOX,DRD1,EDNRA,SEMA3D,EGFR,EPHA5,ETV1,EYA1,TMEM132C,MEX3B,FOXF2,SGIP1,DACH2,MEGF10,GABRB1,IQGAP2,GLRB,TOX3,LPAR4,WIF1,IFI16,LRRTM3,ITGAV,GPR85,NLGN3,PCDH18,TRHDE,PRRX1,PTPRG,TMEM255A,ZMAT4,TSPY26P,ZFHX4,ROBO1,SALL1,SATB1,CSRNP3,LRRTM4,TNFRSF19,DZIP1,NPAS3,ARHGEF9,ADGRL3,PCDHB3,TRPS1,FMN2,SOCS4" Coexpression Atlas geo_heart_2500_K2 geo_heart_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 3.33E-10 1.70E-06 3.46E-09 3.16E-08 266 1138 "SERPINA3,ATP6V0E2-AS1,TKTL1,ACTN2,FAM43B,NDRG2,GALNT16,ADCY5,CCDC85A,ADORA1,ADORA3,RNF150,AGT,C1QTNF1,SPARCL1,LTBP4,KCNT1,ANK2,FGD2,GAS7,AQP4,CHRD,ATP1A2,ATP1A3,ATP2A2,B3GALT2,MYOM1,AZGP1,DNAJC27-AS1,GPR146,LDHD,C1QC,CA4,CACNB2,CAMK2A,CAPN3,CH25H,ENTPD2,MYOM2,LARGE1,CLGN,CRLF1,CHI3L2,ASIC3,LSMEM2,FHL5,FAM149A,AKAP6,CABP1,NRG2,CP,CRY2,TRIM69,CSF1R,PDE4DIP,CST3,PLCXD3,CFAP61,SLC45A1,SEC14L5,SPOCK2,KLHL3,SNAP91,SV2B,DMD,DMPK,DYNC1I1,SLC25A18,ECM2,FAM78B,TOM1,ABCC9,EBF1,EEF1A2,SGK2,HEYL,OPTN,SRPK3,PCOLCE2,RCAN2,IGSF6,ECSIT,HSPA12B,F8,ABCA8,TMEM132C,ST3GAL6,FCGR3A,CAP2,FLNC,FOLR2,TACC2,SORBS1,HVCN1,PDLIM5,RASL10A,KBTBD12,ABLIM2,GABRA4,CHL1,GABRB1,GALNT15,B4GALNT1,IP6K3,HIGD1B,STARD10,ALDH1L1,GFRA1,PCDH17,CSDC2,GGTA1P,GGT5,C1QL1,RAB40B,LILRB4,GPD1,GPR22,GPER1,GRID1,SERP2,GSN,PTPN5,COQ10A,FAM107A,LINC01550,ATOH8,FAM222A,INSYN1,HLF,VSIG4,HAPLN2,HPR,ALDH1L1-AS2,SHISA6,IDH3A,IGF1,ITGA7,ITGAM,KCNJ11,KIFC3,TTYH2,PACRG,MAOB,MAPT,MITF,MT1M,CTNNA3,MYH7,MYL3,NBL1,NCAM1,NFIX,NTRK3,OGDH,CNTN3,PDE1A,PDE1C,PDE2A,PDE3A,PDE4A,PDE1B,PDGFRA,DUSP26,PHKG1,RETREG1,TMEM38A,PLCL1,PLIN1,FXYD1,PMP22,SCHIP1,PRRX1,SEPT4,PPP1R1A,PKIA,MAPK4,FITM2,MASP1,PTH1R,DKFZp779M0652,ACSM5,PYGM,RAB3IL1,SUSD4,ZCWPW1,ROGDI,PRIMA1,RNASE1,MYH14,GLDN,RIMKLA,KCNIP2,DGLUCY,SCN4B,SCN7A,MRAS,SH3BGR,MYO18A,FHOD3,ABLIM3,SLC1A3,SLC4A3,LIMS2,SLC6A1,SLC8A1,SLC11A1,EFHD1,SPHKAP,ABTB1,LIMCH1,FAIM2,PALLD,PDZRN3,PDZD2,WDTC1,ZCCHC24,DBNDD2,ADHFE1,SYNE2,SYN2,COBL,MCF2L,TBX15,PCDHGC5,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,OBSL1,TNS2,HIF3A,TF,ZNF106,THBS4,CDH22,GALNT17,THRA,TIMP4,TLL2,HEY2,TMOD1,DAAM2,TNFRSF1B,TNS1,RASD2,TPM1,WBP2,SYNPO2,PDIA2,FLRT1,TOM1L2,VIPR2,BEST1,ETNPPL,LGI4,ATP6V0E2,NDRG4,SLC26A10,ZBTB16,SLC30A3,SLC17A7,PPP1R3F,FAM47E,SSPN,DPF3,CPNE4" Coexpression Atlas Arv_SC-H9hpx_1000_K5 AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 3.33E-10 1.70E-06 3.46E-09 3.16E-08 138 506 "SYN3,TMEM132B,ADCY2,ADCY8,NLGN4X,SEMA6A,PDZD4,RASL11B,KIF1A,HAP1,SYT6,MAP7,CLDN10,DLGAP1,CHGA,RAB3C,DLGAP3,FAM189A2,FAM19A5,SULT4A1,IGLON5,COL9A1,COL9A3,GAL3ST1,TCEAL2,HS3ST5,ATRNL1,NCAN,RIMS4,CNTNAP2,FAM169A,SEC14L5,NOS1AP,RIMS3,KCTD8,BRINP1,HS3ST4,DPP6,USH1C,AASS,LINC00599,ELAVL2,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GNG4,GPM6B,CECR2,GRIA4,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,BTBD17,ZIC5,IGSF1,TUBB2B,LRRTM3,KCND2,KCNQ2,KIF5A,KIF5C,CAMK2N2,CPNE9,JAKMIP3,SCG3,DDX25,FXYD7,RCOR2,ZDHHC22,PAH,GDAP1L1,CAMKV,PLP1,PSAT1,NECAB2,EPB41L4B,FAT3,PPP2R2B,RAB39A,GDPD2,TMEM145,NKAIN1,RET,RIMKLA,RYR1,SALL1,TMEM200C,SCG5,SH3GL2,SLC1A6,TMEM132D,SLCO1A2,IGSF9B,SNCB,SOX2,SOX3,LHFPL4,HECW1,SEPT3,ZFR2,COBL,TAC3,UNC5D,ENHO,TLL2,RPRM,CLEC2L,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CADM2,XKR7,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.35E-10 1.71E-06 3.48E-09 3.17E-08 191 761 "ACTN1,NDRG2,ADCY5,SORCS1,C1QTNF3,SPARCL1,SRPX,ANK1,PI16,NT5C3B,PHYHD1,KIAA1614,DACT3,ATP1A2,ATP2A2,MYOM1,ADAM23,SEC11C,BCHE,NRP2,GPR146,NIPA1,CA4,CACNA2D1,NGB,CAMK2D,CAMK2G,CAST,CLDN10,ENTPD2,NEURL1,MYOM2,LRRFIP1,CFL2,CHN2,RAB3C,FAM189A2,AKAP6,AKAP5,ABI3BP,GDA,PDE4DIP,SV2B,RABGAP1L,CCDC3,DMPK,CPEB2,ARRDC4,DTNA,ABCC5,ABCC9,SEMA3D,SH3GLB1,CERCAM,SRPK3,ELN,EML1,PLEKHO1,RASGRP2,NCALD,SPEG,MRVI1,NRN1,F3,FABP7,FCGRT,FGF12,PRKAG2,FHL1,CAP2,FLNC,SORBS1,PDLIM5,KHDRBS3,DKK3,GABBR1,ILDR2,DNER,IGSF5,GCNT2,GFRA2,PCDH17,GHR,LYVE1,RAB40B,FERMT2,GPT2,PRUNE2,MCHR1,TPPP,ADAMTS8,GSN,BVES,HLF,HNMT,IFI16,SHISAL1,IL6ST,ITGA7,ITPKB,KCNB1,KCND3,KCNF1,KCNH2,KLHL23,KCNMA1,MBNL1,MBP,IL17D,MMP17,NRBP2,MYH3,MYH6,MYH7,NFIA,ALDH1L2,NPTX2,HCN1,PDE3A,PDE4B,PDE4D,PFKP,TMEM38A,FXYD1,SCHIP1,PRRX1,PILRA,PRKAB2,PRKCB,PSD,PTHLH,ZDHHC14,REV3L,RGS4,TTLL7,ZFHX4,PTGR2,SYNDIG1,RYR3,SCN2A,SCN7A,STUM,HSPA4L,SH3BGR,SH3GL3,FHOD3,ABLIM3,SMTN,LIMS2,SLC15A2,RIMS1,SCN3B,TNIK,FNBP1,DBNDD2,RAP1GAP2,SRPK2,NACAD,INKA2,KANK1,ARHGEF9,SYN2,COBL,POPDC3,CAMSAP2,HIF3A,TEX15,HHIP,ENHO,NACC2,TIMP4,TLR4,ERCC6L2,TNNT1,TNS1,RASD2,TPM1,TPM2,RGMB,SYNPO2,TRPS1,PPIL6,MICAL1,RBFOX3,PLSCR4,RGS7BP,FAM13C,ACTR3B,ADAMTSL3,MSRB3,SSPN" Coexpression Atlas GSM476663_500 "Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1" "Immgen.org, GSE15907" 3.40E-10 1.73E-06 3.51E-09 3.20E-08 117 409 "CPNE2,ACHE,FMNL2,ZNF608,OSBPL1A,CC2D2A,CDC42BPA,LRCH2,ASPH,MYOM1,DST,CACNB2,MAP7,CD81,ADGRG1,B4GALT6,NRXN1,FADS2,ABCG2,AKAP7,MAGED1,ZNF521,GDA,CSF3R,CTNND1,NOS1AP,CYBB,ARHGAP32,DGKG,SIRPA,DNAJC6,MTX3,ARRDC4,EBI3,PLXNC1,CALCRL,MTSS1L,IGSF6,EYA1,ARMCX1,MED12L,NBEA,STAU2,MPP6,NCKAP1,IQGAP2,GATM,GCNT2,TUBA8,GLUL,ADGRA3,GRB10,PRDM5,GUCY1A1,IRAK3,KLF12,HLF,HP,ICA1,DOCK7,LRRCC1,USP54,IL12A,ITGAM,KIT,STXBP5,STMN1,LMO2,MEF2C,MEIS1,ADAM22,MYCN,P2RY13,NEFH,NFIA,NFIX,NPR2,NRGN,OCRL,PBX1,PLCB2,EPB41L4B,LRRC49,DEF8,CNTLN,SLC6A15,SLC25A36,ZNF532,STX1B,CCDC112,PEAR1,ITSN1,PPP1R9A,CCDC88A,SLC14A1,TET1,GKAP1,CABCOCO1,STXBP1,GSE1,FGD4,SYNE2,ANKRD28,DMXL2,PSD3,ARHGEF12,TEK,TGFBR3,TIE1,TLR4,TNS1,NPL,TRIO,STXBP4,SSBP2,VIPR2,PLSCR4" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_1000 kidney_P0_CapMes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.69E-10 1.88E-06 3.81E-09 3.48E-08 166 640 "ABR,ASIC2,NDRG2,RNF157,ZNF608,MTUS1,WDR35,TXNDC16,ALCAM,CEP126,AMPH,OGT,ANK3,VAT1L,SEMA4G,CASK,ATM,ADAM23,BCHE,BCL7A,BMP7,DST,IL33,CA12,CACNA2D1,CACNB4,LONRF2,CDH2,CNTFR,FAM171B,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,ECE2,PHF19,SPOCK2,GSDME,SNAP91,MTX3,DLG4,ARRDC4,DTNA,EDNRA,ELAVL4,C8orf37,CALCRL,KCNMB2,ERBB2,ETV1,RRAGB,EXTL2,EYA1,EZH1,RACK1,ST3GAL6,SLC9B2,FGF1,POLR1B,FGFR1,SCARA3,CAP2,FOXO3,NOP56,WDR83,DPYSL4,TMEM107,STAU2,WASF3,IGSF5,FAXC,GFRA1,GFRA2,FREM1,GLDC,GLRB,TOX3,GLUL,TDRKH,B4GALNT4,CECR2,CNTRL,GRB10,PARD3B,GRIK4,RABL2A,FAM107A,HAS2,NEGR1,HSPA1L,IDH3B,KHK,MEIS2,MEST,POC1B,MMP16,MSI1,MXI1,NCAM1,NEFM,NELL1,NFIX,NME4,NPR2,CNTN3,PRTG,PDE3B,ENPP2,PDYN,PENK,SMOX,PLTP,FAT3,PPP1R1A,CEP41,PRODH,MDGA2,PTN,ZIK1,PYGM,FAM184A,ZCWPW1,RBBP6,TSPY26P,RFX3,RAVER2,ROBO2,TMEM100,UEVLD,RPS6KA2,HUNK,ZNF354C,SALL1,FAM19A1,PPM1E,DZIP1,SLC1A3,SLC4A3,SEPHS1,SLC12A2,GKAP1,LIMCH1,CMTR2,NPAS3,ELOVL4,SULF2,NUDT10,ADAMTS17,CAMTA1,CUX2,PCDHB9,PCDHB3,FRYL,ASXL3,TMOD1,TPM2,STXBP4,CADM1,MKRN3,LAMP5,SLC38A1,SIGLEC10,FZD3,DPF3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.04E-10 2.06E-06 4.16E-09 3.79E-08 81 251 "METAP1D,FMNL2,AXIN2,KLHL13,NR0B1,KCNT1,LRCH2,LCORL,CACHD1,PPP4R4,IGDCC4,PDE8B,NUMB,INSYN2B,ATP2B3,WASF1,CACNA1D,CACNB2,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,MAGI2,CDON,DRP2,KLHL5,EMX2,EPB41L1,MTSS1L,NRN1,OLFM1,GABRA4,GABRB1,NEU3,PCDH11X,GRIK3,IGF1,PLD5,KLHL23,KITLG,SESN3,MTR,NELL2,NPR2,NUCB2,PDE1A,CDK14,SERPINI1,GDPD2,CNTLN,FAT4,ZFHX4,LGR4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ZFP30,SLC4A3,SCMH1,KDM3A,UHRF1BP1L,LHPP,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,CCDC173,ACTR6,DAAM2,TNNT1,FNDC5,LYPD6,NAV2,FRMD6,DPF3" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 4.11E-10 2.10E-06 4.23E-09 3.86E-08 143 531 "ABHD6,ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,KIAA1324,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,SPTBN4,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,C1QC,GPC2,LDLRAD4,REPS2,KCNAB3,CDH18,CDO1,CCPG1,UBE2L6,CLU,VAX2,COL9A2,CRYBB1,CLIP3,CSF1R,SUSD5,PLCH2,DGKG,TIAM2,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,EPB41L1,RAB9B,EPS8,PTK2B,FCGRT,SGIP1,DLL3,STAU2,ABLIM2,FYB1,ZMAT1,DKK3,GAA,ARPP21,TMEM8B,GHR,LYVE1,GLRB,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,ICA1,SCIN,IL11RA,ZNF385B,KCNA6,KLHL23,CREG2,GPR155,MID1,MITF,MOBP,CPNE9,N6AMT1,MYH3,TCEAL5,NELL1,NPY,NPR2,OPCML,CNTN3,PDE4D,PIRT,PLCL1,TRHDE,SDK2,PILRA,NXPH1,PRKAR1B,DIRAS2,MASP1,ACSS3,RALGDS,RAP1GAP,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,MORC4,PRIMA1,MYH14,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,CCDC92,SLC1A2,SLC6A9,SMARCC2,ARHGAP26,IQSEC2,C11orf87,NKAIN2,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,PHF24,FAM189A1,LRRC24,LAMP5,PMEPA1,CADM2,LRP8,PCDH15,CERS6,SSPN,DPF3,PRRT4" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K2 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 4.31E-10 2.20E-06 4.43E-09 4.03E-08 123 438 "ABR,FMNL2,GRAMD1B,KIAA1211,MTA3,OGT,C6orf89,MAGEE2,CCDC181,DPY19L3,KIF1A,MPDZ,CFLAR,SYNJ1,DIRAS1,KALRN,HAP1,CAMK2A,CAMK2D,SCARB1,DCLK1,ARHGAP33,ADGRG1,FADS2,ARMC8,COL4A5,ACBD5,NCAN,RAB39B,MED12,SLC12A6,SNX29,FSD1L,SORBS3,EML1,OLIG2,ANKRD13B,EZH1,CLVS1,FGF12,FGF13,MAD2L2,AFF2,COQ5,NSG2,B3GAT1,GABRB3,GAD1,NEK6,GATM,DCLK2,PCLO,GRIK5,MFSD2A,RNFT2,CELF3,ATG4C,MAN1B1,KCNH2,KLC1,LRRC4B,MBP,SHC3,SCAMP5,PPM1L,SESN3,MXI1,NFIA,GDAP1L1,SNX10,ZNF426,LRP12,MAGEL2,PPM1B,PRKCZ,RELN,PTN,RAB5B,USP47,RAD51D,CARF,CCDC25,SGSM1,ATAT1,RXRA,LRRTM4,PPM1E,AMBRA1,CCDC92,WDR37,PEX26,SIRT2,KBTBD4,ZNF667,SNAP25,KIF13A,TMCC1,TEX2,CAMTA2,MAPK8IP3,ELOVL4,TTBK2,COBL,DDHD2,CAMTA1,KIAA1107,SZT2,SIK3,ZMAT3,BHLHB9,KCTD2,NPL,UCHL1,SLAIN1,LMAN2L,PARP11,ST7,MARCH8,UBE3B,CAMK1G,RNF170,NHSL1,SENP7" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.50E-10 2.30E-06 4.61E-09 4.20E-08 201 813 "SLITRK1,AXIN2,SORCS1,PCDH19,SEMA6A,CEP126,BCAR3,SYT13,DOC2A,FGD2,EPB41L5,AQP4,CDC14B,PDE8B,ZNF599,PROM1,BMP7,BMPR1B,OSGIN2,CA12,CACNA1B,CACNA1D,CALB1,MAP7,MTMR7,LRBA,MAGI1,CRLF1,CBARP,B4GALT6,SLIT2,KIAA1549L,TMEM59L,FADS2,PICK1,HAPLN1,SLC32A1,IPCEF1,PLCH2,PHACTR3,CNTNAP2,FAM169A,KIAA0040,CTH,GREB1,CTNND2,RIMS2,KATNAL2,TOX,AIF1L,MFAP3L,SMG7,CHRDL1,RAB39B,DUSP9,EEF1D,TENM1,PLEKHA1,EMX2,ENO2,DMTN,F3,ACSL4,SPSB4,FGF12,SEMA4D,SPECC1,USP21,RASL10A,PRELID3A,FAM184B,GALC,GAP43,MTHFD2,STARD10,GFRA1,PPARGC1A,KIRREL3,GLDC,TOX3,MAP7D2,CNDP1,B4GALNT4,GRIK1,GRIK2,GRIK4,FAM19A2,MFSD2A,RABL2A,PADI2,FRMD5,IGFBP1,SCIN,SLC35G1,KCNJ16,KCNK1,KIF5C,KIT,L1CAM,C2orf80,GPR155,AQP11,MBP,KITLG,PTOV1,RSPO2,MYCN,LYRM9,MYH7,VWA2,NPTX1,NRCAM,CNTN3,CDK18,PRTG,PFKFB3,SEMA5B,PKM,KCTD15,PLCL1,SLC25A23,HMGCLL1,PLXNB1,MAPK4,GDPD1,LAMA1,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,SUSD4,RASGRF2,GAL3ST4,RET,NUDT11,C12orf49,SGSM1,PRR5L,EMID1,SOX8,FOXRED2,SCN2B,SCN3A,SCN4B,SCN8A,SOX6,SCG5,SH3GL2,SHMT2,HKDC1,FHOD3,ST6GAL1,KBTBD4,SPHKAP,INAVA,KIF21B,SOX11,CAND2,RAP1GAP2,LRRC4,SYT11,NUDT10,TMEM150C,UNC5D,WWC1,WSCD1,CUX2,TCF7,AKNA,PRMT8,DCBLD1,CA14,RPRM,UCHL1,UGT8,SLAIN1,MEAF6,LMF1,VSNL1,NSD2,SF1,FMN2,EMX2OS,ZNF142,FSTL5,ZNF184,DPYSL5,LRP8,TMEM178A,CIAPIN1,SEMA3B,NAV2,FZD3,DOCK8,PHTF2,CAMK1G,VANGL2,AAAS,SPATA13" Coexpression Atlas ratio_ECTO_vs_SC_1000_K3 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 4.96E-10 2.53E-06 5.07E-09 4.62E-08 131 476 "ABHD6,SORCS2,APLP1,CA4,CABP7,CDH2,CDH18,LGI1,IGFN1,NOG,LHX2,CNTFR,COL9A2,NRG2,FAM171B,SEC31B,HAPLN1,ST18,BOC,LYPD1,CCDC3,KIF19,CDON,EMX2,NCALD,CLVS1,TMEM132C,ZIC4,PHYHIPL,ILDR2,DENND2A,GPR162,KIRREL3,DCLK2,CELF3,ZNF491,HES5,LIX1,TMEM240,INSM1,ZNF385B,LRRTM1,NME9,KCNA1,OLFM3,CDH20,LRRC4B,CLEC18A,C1orf194,MAP2,MAP6,MEIS2,SAMD5,SESN3,CCDC80,BCO1,TAGLN3,RSPO2,MDGA1,RTL5,NHLH1,NPY,IGSF11,KCNK10,CNTN3,PAX6,PRTG,ENPP2,HMGCLL1,ASPDH,SDK2,POU3F2,MAPK10,STRC,TMEM255A,FEZF2,PRRT2,RFX4,RLBP1,ZFHX4,KLHDC8A,MELTF-AS1,HSD11B1L,WLS,YJEFN3,FAM182A,SMPD3,SLC30A10,SOX6,ARX,PKNOX2,EFHD1,GKAP1,DMRTC1,UNC80,SOX3,SOX5,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SSPO,VWA3A,PCDHGB6,AZIN2,PCDHB10,PCDHA6,PCDHA3,DICER1-AS1,ASXL3,NR2E1,RIMBP2,TRH,PPIL6,TTPA,CLEC2L,ZIC1,ELFN1,EMX2OS,CRB2,MKRN3,DPYSL5,STMN4,ADAMTS9,DNAH10,FAM182B,CAMK1G,SLC4A10,FAM181A,PRRT4" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2 facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2 Gudmap RNAseq 5.02E-10 2.56E-06 5.12E-09 4.67E-08 283 1230 "TTYH1,SERPINA3,ACTN1,METAP1D,RNF157,AXIN2,HECW2,PCDH19,OSBPL1A,NME5,OSBPL6,SORCS2,SPARCL1,ALCAM,LTBP4,PDZD4,MYH7B,CNIH2,ANXA7,APBB1,APLP1,TNRC6C,CPNE5,KIAA1614,SEMA4G,TMEM263,IGDCC4,ARHGDIG,DACT3,RASL11B,CADM3,NOL4,ADGRB2,NRP2,LDHD,CACNA1G,IL33,LDLRAD4,CACNA2D1,RUNX1T1,ARHGEF25,LDB2,SCARB1,ENTPD6,REPS2,CDC25B,LONRF2,DCLK1,ARHGAP33,EVI5L,LRWD1,NUMBL,CACNA2D2,CHGB,CHN2,NRXN1,QKI,CNR1,WHRN,COL9A3,MAGED1,MYRIP,ZNF521,CNRIP1,ANKRD44,SNCAIP,CSF1,TENM4,SOCS5,GPSM1,ECE2,BOC,ARHGAP24,TOX,ARMCX2,ZEB2,RHOBTB1,SV2A,DLG4,DMD,DNM1,CDON,SHANK1,FIS1,SNX29,SEMA3D,EEF1D,EFNA3,EFNB3,FAM13A,EGFR,SORBS3,CERCAM,ELN,TMEM35A,ENO2,EPB41L2,ANKRD13B,RABEPK,NCALD,EXTL1,CEND1,HSPA12B,F3,TESK2,FGF12,FGF13,FGFR1,SCARA3,ZMYND15,SEMA6C,FOXO3,FLNC,AFF2,TMEM175,CAMKK2,GPR153,NSG1,NRG3,TVP23A,DKK3,GAA,GABRA3,GFRA2,FREM1,CSDC2,GGT7,GHR,DCLK2,GNAO1,ATF7,B4GALNT4,PLPP7,LINGO1,FAM107A,RNFT2,ATOH8,CELF3,HAS2,KLF12,INSYN1,HLF,SYNPO,HMGCL,CFAP126,NEGR1,CPT1C,IGF1,NKD1,IL11RA,SLC6A17,ZNF385B,KCNA6,LRRC4B,CAMK2N2,SMAD9,MAN2A2,MAP2,MATN2,MDFI,MEF2C,MEIS1,MGAT3,MMP16,MN1,MOV10,PTOV1,NRBP2,TAGLN3,MDGA1,MYO7A,NBL1,NCAM1,ZC3H12B,RCOR2,NEFM,NELL1,NFIA,NME4,NPR2,DDR2,NUCB2,PAK3,PCSK5,PDE1B,PFKFB4,CDK14,PGAM2,NLGN3,PKD1,ZFYVE21,FTO,PCDH18,PMP22,SDK2,PPP1R1A,PPP3CC,PRKAR1B,EPDR1,MDGA2,CNTLN,PTH1R,PTPRD,PTPRO,PTX3,RAB3IL1,FAT4,RAP1GAP,ZCWPW1,TSPY26P,PRRT2,LGI2,KIRREL1,ROBO2,PRR5L,ST6GALNAC6,KCNIP3,RTKN,ZNF354C,STX1B,FOXRED2,PRCD,TNFRSF19,SOX6,TRIM46,GALNT10,MRAS,PPM1E,FUZ,DZIP1,FAM81A,SLC6A8,SLC6A9,YPEL4,ARHGEF40,CDK5RAP3,EFHD1,SMARCD3,RIMS1,PALLD,PDZRN3,PDZD2,SOX5,ZNF423,CLSTN2,COLGALT2,EPB41L3,MAPK8IP3,STAC2,PHLDB1,SULF2,ZFR2,PJA1,TCF7,AZIN2,OBSL1,CRTC1,SIK3,CHST8,THRA,HEY1,ANKRD24,KAT6B,TPM1,NPL,TPM2,RFTN2,TUBB2A,CADM1,SLC35A4,FLRT2,PLPPR2,WNT7A,SHD,TMEM178A,SEMA3B,NAV3,PPP1R3F,ITM2C,PLD4,TTC7A,ADAMTS10,FRMD6" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.07E-10 2.58E-06 5.16E-09 4.70E-08 70 206 "GALNT13,RNF150,C1QTNF3,ALCAM,ABCD2,DPP10,DOCK11,IL33,THSD7A,RUNX1T1,LDB2,MYOM2,CDC27,NCOR1,LRIG1,RASSF2,NTM,CALN1,EBF1,EDIL3,EDN3,SEMA3D,TMTC1,ATP8A1,SLC37A3,GABRA1,IQGAP2,GGT5,GLRB,GPR12,GRIA1,GRIA4,GRM3,GUCY1B1,WIF1,RASSF8,KLF12,MSL1,IFI16,ITGAV,KCND2,NOVA1,DDR2,PDE4B,GPR85,PLCL1,SH3KBP1,RELN,FAT4,KIRREL1,CCDC112,CSRNP3,SCN3A,LRRTM4,SCN7A,FAM19A1,DOCK10,ST8SIA1,SLCO1A2,ITPRID2,ADGRL3,PCDHB9,TRO,SSBP2,TTPA,CADM1,AMOT,PCDH20,LYPD6,CERS6" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 5.42E-10 2.76E-06 5.50E-09 5.01E-08 194 780 "RALGAPA1,ABCF1,ACLY,C3orf14,NDRG3,BRAP,PCDH19,TXNDC16,CC2D2A,MAP4K3,PPFIA1,PHYHD1,KIAA1614,TMEM263,ASTN1,ZNF583,ATP6V0A1,BBS2,PROM1,CACNB2,PTBP2,TRIM41,CERS5,CBFA2T2,CDK11B,ZMYM4,MAGI1,DIS3L,CHN1,COG1,C4orf33,NIPBL,SLC4A8,IFFO1,IGDCC3,PREPL,RNF14,PHF14,ARHGAP32,FGFR1OP2,TCAF1,LIN54,KIAA0586,IST1,GIT2,ARMCX4,JAKMIP2,PLEKHM1,HP1BP3,ATN1,PDCD6IP,WDPCP,KLHL5,DCTN4,EMX2,EPB41,GPHN,NSRP1,WAC,ACSL4,TUBA1B,CORO2B,FDFT1,FGFR3,CAMSAP1,FHL1,POLK,UBE2E3,CAP2,EVL,ANKFY1,TMEM175,SMC2,ZNF605,ADGRA1,GABBR1,HIGD1B,C15orf41,MMADHC,GLI2,CBX1,CECR2,RFFL,CIT,KIF3A,RABL2A,GUCY1A2,ADAMTS6,SMAP1,ZNF546,DOCK7,INSM1,JAK1,KIF5C,STXBP5,HECTD2,LSS,MAP4,POC1B,MKLN1,MYO9A,NASP,NFE2L2,NFIX,CNOT4,NUMA1,OCRL,OPA1,OPHN1,GNG2,MTRF1L,PURG,RETREG2,SH3KBP1,DRAM2,CRLS1,PPP2R5C,DIRAS2,GON4L,ANKHD1,ELOVL2,TMEM260,PTX3,ARID4A,RBBP6,ZYG11B,REV3L,GTDC1,KIF7,DCUN1D2,ARMC5,ROBO2,FBXW7,ACER3,FAM161B,CLIP1,FNIP1,CASC3,KIF21A,MYO18A,R3HDM2,ST3GAL3,ANKRD6,DHX30,RUFY2,YPEL4,CCDC88A,BTBD7,TET1,EPC1,ZKSCAN3,MBD5,SPATA7,BDP1,SOX11,ERC1,SRPK2,TAB2,TROVE2,POGZ,ERBIN,SEPT8,SYNE2,VPS13A,MLST8,AGTPBP1,SMG6,DMXL2,TCF7L2,RPGRIP1L,ARHGEF12,CCDC173,HHIP,ERCC6L2,R3HDM1,C9orf85,STXBP4,TSC1,ZKSCAN5,EIF4ENIF1,USP1,MICAL1,RBFOX3,ZFP37,ZBTB38,ZNF184,UPF3A,EMSY,EVI5,RNF103,GAL3ST3,HNRNPA3,NETO2,RNF146" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_CentrlOverEmin_100 e10.5_NeuroEpith_CentrlOverEmin_top-relative-expression-ranked_100 FaceBase_ST1 5.49E-10 2.80E-06 5.57E-09 5.07E-08 38 84 "ASCL1,TTC9B,INA,JAM2,LHX2,SCRN1,JAKMIP2,OLIG1,ELAVL3,OLIG2,EPHB1,FABP7,ZIC4,FOXG1,RUNDC3A,GPM6A,FRMD5,HES5,TUBB2B,LMO1,PACRG,MT3,SCG3,TAGLN3,NFIA,SLC10A4,GDAP1L1,PPP2R5E,NKAIN4,GDPD1,FEZF2,LINC00461,HSPA4L,SOX2,NPAS3,SYT11,CUX2,ZIC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.62E-10 2.87E-06 5.69E-09 5.18E-08 60 166 "SORCS1,USP31,PCDH10,DPP10,APC,ADAM23,NRP2,CACNA1B,CDH10,CNR1,COL9A1,CRHBP,TENM4,VCAN,PLCXD3,BRINP1,MFAP3L,GRIN3A,CALN1,TUBB3,ATP8A1,FOXF2,SGIP1,MEGF10,GABRB1,IQGAP2,SYT17,GFRA1,GFRA2,PCDH17,BACH2,IFI16,KCNMA1,KIF5C,MAP4,RSPO2,NDP,NFIA,NTRK2,CLDN11,PRRX1,MAPK10,PRPH,PTPRO,REV3L,RGS4,ZFHX4,RTN1,ANKRD6,SLC15A2,SNAP25,SCN3B,SOX2,C11orf87,EPB41L3,CUX2,HHIP,RBFOX2,RGMB,NUP214" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2a_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.35E-10 3.24E-06 6.42E-09 5.85E-08 30 58 "TTYH1,NDRG2,ADCYAP1R1,SPARCL1,ATP1A2,CA12,NCAN,LYPD1,EDNRB,FABP7,C1orf61,GPM6B,HAS2,SCRG1,HES5,LIX1,FGFBP3,NFIA,NTRK2,ENPP2,SERPINE2,PLP1,PMP2,PTN,PTPRZ1,BCAN,SLC1A3,SMOC1,WWC1,SEZ6L" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNbM_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.43E-10 3.28E-06 6.48E-09 5.90E-08 21 32 "THSD7A,INA,DCC,EBF1,ELAVL2,ELAVL3,ELAVL4,NRN1,TUBB3,GAP43,GPM6A,STMN2,GRIA2,INSM1,TAGLN3,NCAM1,NNAT,RTN1,SCN3A,SEPT3,CELF4" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k2_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.78E-10 3.46E-06 6.82E-09 6.22E-08 34 71 "SORCS1,DPP10,VSTM2A,INA,CDH10,CHGB,CNR1,FAM171B,CRMP1,JAKMIP2,HS3ST4,GFRA1,PCDH11X,STMN2,GRM3,GRM7,GUCY1A1,GUCY1B1,KLF12,KIF5C,RSPO2,NAP1L2,NDP,NEFM,CLDN11,GPR85,PRPH,FAT4,RTN1,SCN3A,SNAP25,NPAS3,MTCL1,RPRM" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.95E-10 3.55E-06 6.98E-09 6.36E-08 67 195 "ADCY2,ESYT2,SRPX,TMEM263,CADPS,ASPH,CACNA2D1,CNTN1,CNRIP1,AKAP12,ATRNL1,VCAN,ZEB2,GRIN3A,CASP8AP2,EPB41L2,MRVI1,DACH2,GPR153,MEGF10,PCDH11X,RAB40B,GPM6B,GRIA4,RASSF8,HAS2,HNMT,NEGR1,NKD1,KCND3,KCNK2,LAMA2,LIMS1,MEIS1,MMP16,NTRK2,CLDN11,PDE3A,PDGFRA,GPR85,PENK,TMOD2,PRRX1,ZIK1,PTX3,FAT4,ZFHX4,SYNDIG1,LRFN5,SCN2A,SCN3A,SH3GL3,NTNG1,BTBD3,PLCB1,VWC2,CUX2,TCF12,FAM189A1,ZFPM2,TPM2,SYNPO2,TRPC3,TMEFF2,MICAL1,FAM13C,MRPL47" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.66E-10 3.90E-06 7.67E-09 6.99E-08 104 355 "ADCY2,WDR35,ARHGAP20,LRRC4C,CASK,TMEM108,MPDZ,CACNA1G,MYRF,CACNA2D1,KALRN,CBLN1,AP4M1,CDH10,LARGE1,SLIT2,CNTFR,AKAP7,CLIP3,TENM4,ATRNL1,VCAN,BOC,ARMCX2,ZEB2,HEPH,SV2A,DNM1,EDNRA,FABP7,EFEMP1,MEX3B,CAP2,FLNC,FAXC,FREM1,GHR,GLI2,B4GALNT4,GUCY1A2,ADAMTS6,GUCY1A1,GUCY1B1,HAS2,NKD1,MATN2,CHIC1,MEIS1,MEIS2,MMP16,TCEAL5,NCAM1,ZC3H12B,NEFM,NFIA,NNAT,NME4,DDR2,PBX1,PDE3A,PDGFRA,PIK3R1,PCDH18,PRRX1,FAT3,SH3KBP1,SYTL2,LAMA1,PTN,ZIK1,PTX3,RIC8B,RNASEL,ROBO2,ARMH4,MEG3,ZNF354C,CCDC112,SATB1,SCN2A,DZIP1,PKNOX2,ZNF334,SMARCE1,PALLD,PDZRN3,ZCCHC24,SOX11,CAND2,KLHL7,CUX2,PSD3,TGFBR3,ASXL3,TPM1,STXBP4,TRPS1,SSBP2,TMEFF2,PLEKHH2,VLDLR,ZFP37,ZNF184,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.42E-10 4.29E-06 8.42E-09 7.67E-08 193 779 "RALGAPA1,ABAT,ABR,ASIC2,METAP1D,ADCY8,USP31,INTS2,NR0B1,AMPH,ANK3,APC,VAT1L,SFMBT2,SEMA4G,ZSCAN18,ATP1A2,BBS2,BCHE,BMP7,CDK5R1,OSGIN2,IL33,CACNA2D1,CACNB4,KALRN,CH25H,CDH2,FAM19A5,COL9A1,ZFP28,NSL1,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,GREB1,RIMS2,PYGO1,KATNAL2,CENPL,SPOCK2,GSDME,SNAP91,MTX3,RAB39B,DYNC1I1,ARRDC4,DTNA,HEYL,KMT5B,ABI2,ELAVL4,TMEM35A,EIF1,KCNMB2,SPEG,CDHR1,RCSD1,ADGRV1,EYA1,EZH1,ST3GAL6,SLC9B2,FGF1,POLR1B,FGFR1,SCARA3,CAP2,SGIP1,SMC2,FAM49B,PRELID3A,DACH2,TVP23A,MEGF10,GABRB3,SRCAP,GFRA1,BRD8,GLDC,KIAA1958,TDRKH,FUT10,B4GALNT4,CECR2,GRB10,PRDM5,FAM19A2,PSIP1,FAM107A,HAS2,FRMD3,NEGR1,RBPJ,ITIH2,KIF5C,NCOA7,CHIC1,MKLN1,MSI1,MYBPC1,FXYD6,NASP,NELL1,NPTX1,NRDC,OXTR,CNTN3,PRTG,PIK3C2A,ANKRD16,RC3H2,ING3,FAT3,NXPH1,PPP1R1A,KANSL1,CEP41,EPDR1,MAPK8,PIGG,PTHLH,NKAIN1,PPP2R3C,CCDC40,FAM184A,ENOX1,GAL3ST4,CRTAC1,REV3L,ROBO2,PRR5L,RIMKLA,RPS6KA2,RPS20,SALL1,MAPK12,HES6,ZFP2,SFPQ,ASRGL1,SUPT20H,TRA2B,HSPA4L,PPM1E,DZIP1,ANKRD6,SLC1A3,DHX30,SLC12A2,IFT122,MBD5,FAM126B,SOX11,C11orf87,CLASP2,NEK4,CEP68,ANKRD28,CAMTA1,CAMSAP2,WSCD1,TCF4,TRIM2,SZT2,RALYL,PCDHB9,FRYL,ZFP91,ERCC6L2,RBFOX2,TPM2,RGMB,STXBP4,TSN,SSBP2,RPL7L1,SLAIN1,NSD2,RICTOR,XRCC4,ZNF184,ZFAND5,INTS3,LRP8,PCBP4,PHTF2,NUP214,NETO2,SOCS4" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500 facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500 Gudmap RNAseq 9.03E-10 4.61E-06 9.02E-09 8.22E-08 360 1641 "TTYH1,SERPINA3,ABAT,EMILIN3,ACTN1,METAP1D,NDRG2,ADCY2,RNF157,AXIN2,HECW2,PCDH19,OSBPL1A,NME5,OSBPL6,SORCS2,C1QTNF1,SPARCL1,ALCAM,SRPX,ARHGAP20,LTBP4,PDZD4,MYH7B,CNIH2,ANXA7,APBB1,APLP1,TNRC6C,APP,CPNE5,KIAA1614,SEMA4G,TMEM263,IGDCC4,ARHGDIG,DACT3,RASL11B,CADM3,NOL4,MYOM1,ADGRB2,RGS11,NRP2,LDHD,C1QC,CACNA1G,IL33,LDLRAD4,CACNA2D1,RUNX1T1,ARHGEF25,KYAT1,LDB2,SCARB1,ENTPD6,REPS2,CDC25B,LONRF2,DCLK1,ARHGAP33,EVI5L,CDO1,LRWD1,UBE2L6,NUMBL,CACNA2D2,CHGB,CHN2,NRXN3,NRXN1,QKI,ARHGEF6,CNR1,WHRN,COL9A1,COL9A3,MAGED1,ABI3BP,MYRIP,ZNF521,CNRIP1,ANKRD44,SNCAIP,CSF1,TENM4,FEZ1,SOCS5,SDC3,GPSM1,ECE2,BOC,ARHGAP24,TOX,DGKB,SPOCK2,ARMCX2,ZEB2,RHOBTB1,SV2A,DLG4,DMD,DNM1,CDON,SHANK1,FIS1,SNX29,SEMA3D,EEF1D,EFNA3,EFNB3,FAM13A,EGFR,SORBS3,CERCAM,ELN,TMEM35A,ENO2,EPB41L2,RCAN2,LRRC17,ANKRD13B,RABEPK,NCALD,TLR7,RASL12,EXTL1,CEND1,HSPA12B,F3,CHST15,FCGRT,TESK2,FGF12,FGF13,FGFR1,FGFR3,SCARA3,ZMYND15,SEMA6C,FOXO3,FLNC,AFF2,TMEM175,CAMKK2,GPR153,NSG1,TPPP3,NRG3,TVP23A,DKK3,GAA,GABRA3,GDF9,GFRA2,FREM1,CSDC2,GGT7,GHR,LYVE1,DCLK2,LOXL3,GNAO1,ATF7,B4GALNT4,PLPP7,GRM7,GSN,LINGO1,FAM107A,RNFT2,GUCY1A1,ATOH8,CELF3,HAS2,KLF12,INSYN1,HLF,SYNPO,HMGCL,CFAP126,NEGR1,CPT1C,IGF1,NKD1,IL11RA,SLC6A17,ZNF385B,LRRTM3,KCNA6,LRRC4B,CAMK2N2,SMAD9,MAN2A2,MAP2,MATN2,MDFI,SHC3,MEF2C,MEIS1,MGAT3,MMP16,MN1,MOV10,CD200,CCDC80,PTOV1,NRBP2,TAGLN3,MDGA1,MX1,MYO7A,NBL1,NCAM1,ZC3H12B,RCOR2,NEFM,NELL1,NFIA,NFIX,NME4,NPR2,NRGN,DDR2,NUCB2,P2RX7,PAK3,PCSK5,PDE3A,PDE1B,PDGFRA,PENK,PFKFB4,CDK14,PGAM2,NLGN3,SERPINE2,PIK3CD,PKD1,ZFYVE21,PLCD1,FTO,FXYD1,PCDH18,PLTP,PMP22,PRRX1,SDK2,PPP1R1A,PPP3CC,PRKAR1B,EPDR1,MDGA2,CNTLN,PTH1R,PTN,PTPRD,PTPRO,PTX3,RAB3IL1,FAT4,RAP1GAP,ZCWPW1,ZMAT4,TSPY26P,PRRT2,RGS4,LGI2,KIRREL1,ROBO2,PRR5L,EMID1,SOX8,ST6GALNAC6,KCNIP3,RTKN,ZNF354C,STX1B,FOXRED2,PRCD,TNFRSF19,SOX6,TRIM46,GALNT10,MRAS,FAM102A,PPM1E,DOCK10,FUZ,NTNG1,DZIP1,SLC1A3,FAM81A,SLC6A8,SLC6A9,YPEL4,ARHGEF40,CDK5RAP3,EFHD1,SMARCD3,RIMS1,PALLD,PDZRN3,PDZD2,SOX5,ZCCHC24,ZNF423,CLSTN2,COLGALT2,EPB41L3,NKAIN2,MAPK8IP3,STAC2,PHLDB1,SULF2,ZFR2,PJA1,PDLIM2,SATB2,TCF7,AZIN2,OBSL1,TNS2,CRTC1,GPRIN3,SIK3,TF,CHST8,GALNT17,THRA,ENHO,HEY1,DAAM2,ANKRD24,KAT6B,TNS1,TPM1,NPL,TPM2,IL34,RFTN2,TUBB2A,CADM1,SLC35A4,FLRT2,PLPPR2,WNT7A,ZBTB16,SHD,TMEM178A,SEMA3B,NAV3,PPP1R3F,ITM2C,PCBP4,PLD4,TTC7A,ADAMTS10,SSPN,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.40E-10 4.79E-06 9.36E-09 8.53E-08 43 103 "PCDH10,INSYN2B,RNF182,CH25H,RUNX1T1,CBLN1,DCLK1,CDO1,CRLF1,ZNF521,TOX,PITPNC1,MAGI2,DLX1,DRD1,TENM1,EPHA5,TMEM132C,FOXF2,NBEA,MEGF10,GABRA4,DNER,GLRB,WIF1,IFI16,LRRTM3,NLGN3,PRRX1,EPB41L4B,FIGN,ZFHX4,ROBO1,SALL1,CSRNP3,ANKRD6,KLHL7,TAC1,UNC5D,PCDHB15,PCDHB3,ASXL3,FMN2" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.61E-10 4.90E-06 9.55E-09 8.71E-08 59 164 "EMILIN3,ADRB2,TMEM263,CADPS,ATP2B1,MYOM1,CA8,CACNA2D1,CFL2,CNTN1,COL9A1,VCAN,PLCXD3,ZEB2,RABGAP1L,EPB41L2,NCALD,MRVI1,CAP2,SYNCRIP,SORBS1,SMC2,PDLIM5,DACH2,PNMA2,DKK3,MEGF10,GFRA2,FERMT2,NEGR1,LIMS1,HECTD2,MEIS1,MKLN1,NFIA,NPTX2,CLDN11,CNTN3,PCDH9,NALCN,PIK3C2A,KANSL1,PTX3,REV3L,LGI2,RYR3,SH3BGR,SMOC1,VWC2,HHIP,ERCC6L2,RBFOX2,TPM2,RGMB,SYNPO2,TRPS1,SSBP2,VLDLR,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.00E-09 5.10E-06 9.92E-09 9.04E-08 76 234 "GALNT13,RNF150,C1QTNF3,ALCAM,ABCD2,DPP10,ASPH,DOCK11,IL33,THSD7A,CAMK2D,LDB2,MYOM2,REPS2,LRIG1,RASSF2,NTM,CALN1,ABCC9,EBF1,EDN3,EDNRA,SEMA3D,TMTC1,EGFR,ADGRV1,CORO2B,ATP8A1,SLC37A3,GABRA1,IQGAP2,GGT5,GLRB,GPR12,GRIA1,GRIA4,GRM3,GUCY1B1,WIF1,RASSF8,HNMT,MSL1,IFI16,ITGAV,KCND2,VWA5A,LSAMP,MMP17,NOVA1,PDE4B,GPR85,PIK3R1,PLCL1,PCDH18,SH3KBP1,LRRN3,RELN,FAT4,FIGN,CSRNP3,SCN3A,LRRTM4,SCN7A,FAM19A1,ST8SIA1,SLCO1A2,ITPRID2,NXT2,RGL1,RHBDL3,PCDHB9,TLR4,TRO,SSBP2,PCDH20,PLSCR4" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000_k2 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.05E-09 5.35E-06 1.04E-08 9.48E-08 75 230 "ADD3,PNMA8B,TAOK1,PKP4,DOCK11,BACH1,SGCE,ZNF445,SRSF11,CHM,SLIT2,NMT2,COL4A5,RBM39,FGFR1OP2,GAPVD1,TCAF1,KIAA0586,AIF1L,ZC3H11A,CDON,EDNRA,EIF4G1,CALCRL,EPB41L2,SRRM1,MEX3B,ANKFY1,SMC2,APOPT1,GABRB1,SRCAP,LPAR4,DIDO1,MIER3,MAP4,CHIC1,MEIS1,MMP16,SAMD5,MSI1,NASP,CNOT4,OCRL,PCDH9,OLA1,PIK3R1,PLEC,KANSL1,MAPK8,C1orf54,RNASEL,TMLHE,MEG3,NCBP3,ATXN2,TRA2B,CHD9,NAPB,SCMH1,ZC3H13,PRRC2C,SYNE2,AHCYL2,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,FLRT2,ADAMTS9,NAV2,SNX27,GAN,SENP7" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.09E-09 5.54E-06 1.07E-08 9.79E-08 18 25 "VAT1L,INA,CRMP1,FGF13,NSG1,GFRA2,STMN2,LIX1,L1CAM,NELL2,SLC10A4,RET,RGS4,SCG5,SYT11,SYT1,UCHL1,STMN4" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.14E-09 5.81E-06 1.12E-08 1.02E-07 116 412 "ADCY2,KLHL13,OSBPL6,ALCAM,ARHGAP20,PCDH10,FAM135A,DGKD,CADPS,ATP2B1,ADGRB2,IL33,CACNA1D,CACNA2D1,CALB1,CANX,LDB2,CD86,CFL2,NRXN3,LY86,CNTN1,COL9A1,CNRIP1,AKAP12,CRYM,ATRNL1,VCAN,ZEB2,NTM,PLXNC1,CALCRL,EPB41L2,RASGRP2,EPHB1,NCALD,MRVI1,HSPA12B,SMC2,DACH2,TVP23A,DKK3,GABRA1,GALC,GAP43,FREM1,RAB40B,GRB10,GRIA1,GRIA4,GRM7,GUCY1A1,HAS2,UBE2QL1,ZHX1,NEGR1,SCIN,IL11RA,TUBB2B,KCND3,LAMA2,MATN2,MEIS1,MMP16,CCDC80,MSR1,NCAM1,NDP,NFIA,CNOT4,CLDN11,PCDH8,PCDH9,PDE3A,GPR85,PENK,PIK3C2A,TRHDE,PRRX1,MBOAT7,KANSL1,NKAIN4,PTPRO,PTX3,ZYG11B,REV3L,LGI2,SYNDIG1,LRFN5,SCN7A,ST8SIA1,CXXC4,SNCA,MYCBP2,SAMSN1,STX1A,CAMSAP2,PDLIM2,MGRN1,ANO4,VWC2,CUX2,ENHO,ERCC6L2,RBFOX2,RGMB,SYNPO2,SSBP2,TMEFF2,FLRT2,VLDLR,PROCA1,SPIRE1,NAV3,MSRB3,NETO2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.17E-09 5.97E-06 1.15E-08 1.05E-07 105 362 "NDRG2,GRAMD1B,ALCAM,ARHGAP20,LTBP4,DDX3Y,TMEM108,CACNA1G,MYRF,CACNA2D1,RUNX1T1,ARHGEF25,CBLN1,LDB2,REPS2,LGI1,SLIT2,CLU,CNTFR,AKAP5,CLIP3,SNCAIP,TENM4,MICAL2,VCAN,PLXNA4,RIPOR2,ARHGAP24,ARMCX2,ZEB2,DNM1,EDNRA,HEYL,EGFR,PLXNC1,LRRC17,EYA1,NRN1,FAM198B,FABP7,DLC1,FLNC,AFF2,GABRA4,GFRA2,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,GPM6A,GPM6B,GRIA4,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,HPSE2,IGF1,LRRTM3,KCND2,LAMA2,MAP2,MATN2,MEIS1,NEXMIF,NCAM1,NFIA,PAK3,PCDH9,PDE1A,PDGFRA,FXYD1,PCDH18,PLTP,PMP22,PRRX1,FAT3,SH3KBP1,LRRN3,MASP1,LAMA1,PTCH1,PTN,TMEM255A,ROBO2,MEG3,NTNG1,PKNOX2,SORCS3,PALLD,SULF2,ADGRL3,ZFPM2,HHIP,TNNT1,TPM1,SSBP2,TMEFF2,PLEKHH2,VSNL1,STOX2,WNK3,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.23E-09 6.29E-06 1.21E-08 1.11E-07 183 733 "ABAT,EMILIN3,RTL9,SEMA6A,SRPX,MARCH4,ANK1,KCNAB2,APBB2,CACHD1,SLC7A14,CDK10,PDXK,IGDCC4,SPTBN4,RASL11B,BMPR1B,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDO1,CRLF1,DIS3L,CLTB,COL9A2,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,ATRNL1,GPSM1,BOC,ARHGAP24,DGKG,GSDME,RHOBTB1,CCDC3,GRIN3A,DNM1,USP3,ABCC9,MBNL2,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,DENND4A,ETV1,HSPA12B,FCGRT,FDFT1,TESK2,FECH,SCARA3,FOXF2,SGIP1,NBEA,ZBED3,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,TRAF3IP2,ZNF274,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,WIF1,BACH2,SYNPO,IDH3B,IL11RA,INPP1,ITPKB,JAK2,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PIRT,PDGFRA,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,RGS10,ZFHX4,MRAP2,BAALC,LRRK2,PLPPR3,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,ELMO2,SMARCC2,IFT122,PDZRN3,DOP1A,ZHX3,CDK19,COLGALT2,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,EHBP1,TCF4,SATB2,ZFP90,SYNE1,PHF24,CRTC1,HIF3A,ASXL3,DAAM2,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF708,ZNF32,FTSJ1,PMEPA1,NAV3,CERS6,MSRB3,ADAMTS10,SSPN,KLHDC1" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.24E-09 6.32E-06 1.22E-08 1.11E-07 120 431 "RNF157,SLC12A5,FAM135A,AMPH,EPB41L5,VAT1L,CASK,ASTN1,ATP1A2,ADAM23,BMP7,KALRN,PTBP2,CDH2,TBRG4,FAM189A2,MAP4K4,COL9A1,CRMP1,CRYM,PPP1R16B,CTH,NRSN1,ECE2,KATNAL2,PHF19,SPOCK2,BRINP1,SMG7,SNAP91,GRIN3A,RAB39B,DUSP9,USH1C,EFNA3,ELAVL4,KCNMB2,SLC43A2,CDHR1,EYA1,SPSB4,FGFR1,PSD2,DPYSL4,HVCN1,PRELID3A,NSG2,DACH2,TVP23A,MEGF10,GABRA1,CHL1,DENND2A,GALC,GFRA1,KCNMB4,GP1BB,B4GALNT4,GRM3,FAM19A2,FAM107A,HAS2,INSM1,KCNK2,KIF5C,LSAMP,MEIS1,MEIS2,TAGLN3,NELL1,NPTX1,NRCAM,NTRK2,PBX1,PCDH8,PRTG,HMGCLL1,EPB41L4B,CEP41,DIRAS2,PTX3,NKAIN1,CEP97,CCDC40,GAL3ST4,ZMAT4,FIGN,C12orf49,PRR5L,RPS6KA2,HUNK,RYR1,SALL1,MAPK12,CSRNP3,DRAXIN,ZNF821,ANKRD6,SLC1A3,SLC4A3,SLC9A5,ZNF334,CAND2,C11orf87,CLSTN2,TAL1,ANO4,CUX2,AKNA,ASXL3,TP53BP1,TPM2,CA14,TTPA,SF1,ZNF24,ZNF184,LRP8,PCBP4,NETO2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.26E-09 6.44E-06 1.24E-08 1.13E-07 38 86 "SORCS1,PCDH10,FAM135A,VAT1L,RNF182,LDLRAD4,DCLK1,SLC35F1,ERC2,HDAC9,TENM1,EPHA5,EYA1,TMEM132C,FOXF2,SGIP1,DACH2,DNER,WIF1,IFI16,MYH3,NAP1L2,GPR85,HMGCLL1,PRRX1,FAT4,ZFHX4,CSRNP3,LRRTM4,FAM19A1,NTNG1,ANKRD6,NPAS3,ELOVL4,ADGRL3,PCDHB3,RPRM,SOCS4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K4 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.29E-09 6.56E-06 1.26E-08 1.15E-07 154 592 "EMILIN3,RTL9,SEMA6A,SRPX,MARCH4,KCNAB2,IGDCC4,SPTBN4,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDH18,CDO1,CRLF1,CLTB,COL9A2,COL9A3,ABI3BP,ANKRD44,CLIP3,SNCAIP,SUSD5,ATRNL1,PYGO1,BOC,DGKG,C8orf34,CCDC3,GRIN3A,DNM1,USP3,ABCC9,MBNL2,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,DENND4A,FCGRT,FDFT1,TESK2,SCARA3,SGIP1,SYT3,NBEA,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,JPH4,CPLX2,NEU3,FREM1,ZNF276,RAB30,GRIK4,WIF1,SYNPO,AGBL5,ICA1,IL11RA,JAK2,KHK,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,CD200,CPNE9,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE1A,PDE3A,PDE4D,PIRT,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,CNTLN,ACSS3,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,ZFHX4,MYH14,MRAP2,LRRK2,DGLUCY,ATXN1,LRFN5,MRAS,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,YPEL4,SLC8A1,SMARCC2,PDZRN3,DOP1A,ARHGAP26,CDK19,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,KAZN,UNC5D,ADGRL3,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,PIK3R5,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,PMEPA1,NAV3,CERS6,SSPN,KLHDC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.29E-09 6.59E-06 1.26E-08 1.15E-07 133 492 "NCKAP5,GALNT13,ESYT2,HECW2,OSBPL1A,OSBPL8,FAM135A,LCORL,APAF1,USP37,TMEFF1,ASPH,SCAPER,DCLK1,CDO1,SLIT2,PLAA,BTF3L4,ZNF521,ANKRD44,NCOR1,ABCG1,LRIG1,CSNK1G3,VCAN,PDE4DIP,ERC2,APPL1,PNPLA8,PYGO1,HDAC9,TOX,PITPNC1,ZEB2,CEP170,BLOC1S6,SPOCK3,DRD1,SEMA3D,EGFR,TENM1,CALCRL,EPHA5,DENND4A,ZIC4,SCML2,DLC1,GORAB,FOXF2,MEGF10,GABRA4,ARPP21,DNER,PPARGC1A,GLRB,GLS,TOX3,RAB40B,ADGRA3,GPD2,GPR12,LPAR4,GRIA2,PSIP1,MAP4K5,FRMD3,MIER3,IFI16,LRRCC1,KCNA4,LSAMP,MYO5A,DDR2,PAK3,PCDH8,ENPP2,NLGN3,LRP12,PRRX1,ING3,EPB41L4B,PPP3CB,MAPK8,GRAMD1C,ZIK1,PTPRE,TMEM255A,OXR1,ARID4A,GAL3ST4,FIGN,KLHL11,C12orf49,ROBO1,RPS20,SATB1,CSRNP3,LRRTM4,FNIP1,SFPQ,WDR37,ZNF365,SLC1A3,CCDC88A,SLC12A2,CMTR2,FAM126B,SON,HECW1,LMO3,TROVE2,ELOVL4,TTBK2,KLHL7,ARHGEF9,ADGRL3,TBX15,PCDHB15,PSD3,PUM2,TMPO,SSBP2,UGT8,TBC1D15,WIPF1,PCDH20,ZBTB14,ZNF711,PARP11,GOPC,PHTF2,CBLN2,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.31E-09 6.69E-06 1.28E-08 1.16E-07 130 478 "NCKAP5,GALNT13,ESYT2,HECW2,OSBPL1A,PCDH10,FAM135A,LCORL,APAF1,PLA2G4C,ASPH,RASL11B,DYNLL1,BLM,SCAPER,DCLK1,LARGE1,CDO1,SLIT2,PLAA,SLC4A7,ANKRD44,NCOR1,VCAN,PNPLA8,PYGO1,HDAC9,TOX,CENPL,PITPNC1,DCT,TIAM2,MAGI2,BLOC1S6,RHOBTB1,SPOCK3,ANKRD46,EGFR,SRPK3,DMTN,EPHA5,DENND4A,TBC1D16,ZIC4,SCML2,DLC1,TESK2,GORAB,SCARA3,FOXF2,GABRA4,GAD1,FAM120B,DNER,GLRB,TOX3,RAB40B,ADGRA3,GPR12,LPAR4,GRIA2,PSIP1,IFI16,KCNA4,LSAMP,GPR155,MYH3,MYO5A,NEK1,VWA2,DDR2,PAK3,PCDH8,ENPP2,PFKFB3,NLGN3,LRP12,PRRX1,ING3,EPB41L4B,ZIK1,PTPRE,PEX2,TUG1,TMEM255A,ZNF493,OXR1,ARID4A,GAL3ST4,SEC61A2,ZFHX4,C12orf49,ROBO1,RPS20,SATB1,CSRNP3,LRRTM4,TNFRSF19,PPM1E,SLC1A3,YPEL4,CCDC88A,ATF7IP,SON,KIF1B,TROVE2,CLSTN2,TTBK2,KLHL7,ZC3H4,ARHGEF9,UNC5D,ADGRL3,TBX15,PCDHB15,PSD3,PUM2,FBXL16,TMPO,SSBP2,UGT8,TBC1D15,WIPF1,PCDH20,ZBTB14,PARP11,PAK5,CERS6,CBLN2,SOCS4" Coexpression Atlas gudmap_developingGonad_P2_epididymis_500 DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.41E-09 7.20E-06 1.37E-08 1.25E-07 112 395 "ADCY8,ADD1,ADD3,PNMA8B,C1QTNF3,SRPX,ARHGAP20,LTBP4,LCORL,PKP4,DDX3Y,ATP1A2,ATP2B1,MYOM1,BACH1,JAZF1,IL33,VSTM2A,RUNX1T1,RGN,DCLK1,ZNF445,SRSF11,CHM,PLAA,COL4A5,CP,RBM39,PUM1,RIPOR2,AIF1L,ZEB2,MFAP3L,ZC3H11A,GSDME,CHRDL1,EDNRA,EIF4G1,ELN,EMX2,EPB41L2,LRRC17,SRRM1,ETV1,SCML2,EFEMP1,FGF1,SMC2,APOPT1,GABRA4,GABRB1,ILDR2,GAD1,DNER,CSDC2,LYVE1,GLUL,CNDP1,LPAR4,RASSF8,KCNC2,KCND3,LAMA2,MAOB,MAP4,MATN2,CHIC1,MEIS1,MEIS2,SAMD5,MYH3,NFIX,VWA2,NPY,PCDH9,PENK,NALCN,PIK3R1,FXYD1,PLTP,PRRX1,FAT3,MAPK8,C1orf54,VEPH1,RNASEL,LGI2,TMLHE,MRAP2,MEG3,ATXN1,SFPQ,TRA2B,ARX,TET1,ZC3H13,TROVE2,PRRC2C,SYNE2,PCDHB9,HHIP,CBX5,TNS1,NR2C2,SSBP2,UBE3A,UBTF,FLRT2,VLDLR,ADAMTS9,GAN,SENP7" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_500 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.52E-09 7.77E-06 1.48E-08 1.35E-07 121 437 "FMNL2,HECW2,KLHL13,NR0B1,SPARCL1,ARHGAP20,KCNT1,CACHD1,PPP4R4,ZSCAN18,TMEM108,ATP2B3,MYRF,CACNB2,CALB1,RUNX1T1,CBLN1,CDH10,DCLK1,CDH18,MAGI1,CNTFR,AKAP5,ZNF521,HAPLN1,CLIP3,TENM4,ATRNL1,VCAN,PLXNA4,DOCK4,DAPK1,DCT,DNM1,CPEB2,DRP2,EDNRA,PLXNC1,C8orf37,EMX2,MTSS1L,CEP85L,F3,FABP7,TUBB4A,FLNC,GABRA4,FREM1,GHR,PCDH11X,GPR37,BVES,GUCY1A2,GUCY1A1,TCEAL6,SHISA6,KCND2,KLHL23,MAP2,MATN2,MEIS1,KITLG,AFF1,CCDC80,MTR,NCAM1,NEFM,NFIA,NME4,NUCB2,PDE1A,PDGFRA,PFKFB3,SERPINI1,ZNF655,PCDH18,PRRX1,PPP2R2B,RASGEF1B,SYTL2,LAMA1,PTN,TMEM255A,RADX,ROBO1,ROBO2,TMEM206,LGR4,MEG3,HUNK,KCNIP1,RASA3,ST8SIA1,SLC4A3,PKNOX2,PALLD,KDM3A,UHRF1BP1L,PEG10,SMOC1,ST5,ADGRL3,OBSL1,CCDC173,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,BEX4,TNNT1,TRPS1,FNDC5,TMEFF2,PLEKHH2,VSNL1,PCDH20,ZNF711,LYPD6,WNK3,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k4 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.54E-09 7.83E-06 1.49E-08 1.36E-07 39 90 "USP31,VAT1L,CACNA1B,CHGB,CNR1,CNTN1,TMEM130,SPOCK3,TUBB3,FOXF2,DACH2,DNER,GNG4,STMN2,WIF1,IFI16,KIF5A,KIF5C,MAP4,MYH3,NEFM,NFIA,DDR2,PIRT,PRRX1,MAPK10,PRPH,RGS4,ZFHX4,RTN1,SCN3A,SNAP25,SCN3B,C11orf87,CLASP2,EPB41L3,PCDHB7,RBFOX2,FSTL5" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.57E-09 8.00E-06 1.51E-08 1.38E-07 234 991 "SDE2,ABCF1,SLITRK1,ADCYAP1R1,AXIN2,PLEKHH1,PTCHD1,INTS2,KIAA1324,DISP3,TAOK1,ALAD,EPB41L5,ATM,ATP1A1,ATP2A2,DOCK11,TTLL9,FGF17,NRP2,ZNF599,PROM1,CA4,CA12,HAP1,MAP7,CBLN1,INA,TBRG4,ADGRG1,JAM2,CLCN3,NRXN2,FAM19A5,CNTFR,SLC4A7,IGDCC3,CDC42BPB,CRMP1,CRYM,NCAN,FAM169A,SLITRK5,CTH,GREB1,CTNND2,RIMS2,KATNAL2,TOMM20,DAPK3,JAKMIP2,DDX46,SMG7,SRGAP3,KBTBD11,CHRDL1,DTNA,ST8SIA3,EFNA2,PLXNC1,LPAR6,EIF4G1,ELAVL2,PLEKHA1,CERCAM,LRRC23,EPHB1,PIPOX,RRAGB,EXTL2,ADGRV1,CD320,REEP2,FABP7,ACSL4,TUBB4A,CEP78,SPSB4,FGF12,FHL1,SEMA4D,NOP56,ZCCHC17,SORBS1,PDLIM5,GPR153,DLL3,FUT9,B3GAT1,PHYHIPL,GABRB3,ILDR2,AHCYL1,MTHFD2,SRRM4,GART,AHDC1,TXNL4A,TCERG1,GLDC,TOX3,MAP7D2,GPR19,LPAR4,CECR2,PCLO,TUBA1C,STMN2,GRIK3,CIT,RNF165,MFSD2A,SOX21,CELF3,TOX2,FRMD5,DDX19B,ELOVL5,USP51,HSP90AA1,CELF5,ATCAY,NKD1,ZIC5,HES5,LRRTM1,SLC35G1,CDH20,KIT,IPO5,KTN1,AQP11,TM6SF1,MSI1,SCG3,MYCN,NAP1L1,NASP,RCOR2,NNAT,NOVA1,NRCAM,NTRK2,ODF2,PRTG,FAM98B,PFKP,NLGN3,SEMA5B,PKM,PLP1,SLC25A23,PLTP,MAGEL2,POLR2F,POU3F4,IRX1,PPP5C,MAPK10,PRODH,PROX1,SLC22A23,LAMA1,GDPD2,ELOVL2,PTPN13,EML5,CCDC40,SUSD4,FIGN,RFX4,RPL15,RTN1,SALL1,TNFRSF19,HSPA4L,SCG5,KIF21A,SHMT2,FHOD3,NUBPL,PKNOX2,SLC20A2,SLCO1A2,SNRPN,SOX2,BDP1,DOK5,NMNAT2,BEX1,LMO3,PBLD,NEK4,KANK1,AJAP1,SYN1,SYP,SYPL1,ANKRD28,MTCL1,MCF2L,WWC1,WSCD1,ACSL6,WASHC4,TMEM121,ZNF106,BEX4,PRMT8,CA14,HSPBP1,CADM1,UBE3A,SLAIN1,FLRT1,FAM181B,MGAT5B,VSNL1,RBFOX3,ZIC1,ZIC2,ZIC3,KCNT2,ZBTB16,DPYSL5,LAMP5,CA10,SLC38A1,NAV2,PCBP4,FZD3,AAAS,FXR1,SPATA13" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.65E-09 8.42E-06 1.59E-08 1.45E-07 117 419 "KDM5D,KLHL13,NR0B1,ARHGAP20,CACHD1,LRRC4C,DDX3Y,MYRF,CACNA2D1,CALB1,KALRN,CBLN1,CDH10,DCLK1,LARGE1,SLIT2,CNTFR,ZNF521,HAPLN1,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,DCT,ZEB2,SV2A,DNM1,DRP2,TSPAN5,EDNRA,SEMA3D,PLXNC1,EMX2,MTSS1L,FAM198B,FABP7,EFEMP1,FGFR1,CAP2,FLNC,GABRA4,DENND2A,FREM1,GHR,GLI2,PCDH11X,ADGRA3,GPM6B,GPR37,GUCY1A2,GUCY1A1,GUCY1B1,NKD1,KCND2,KLHL23,MATN2,MEIS1,MEIS2,KITLG,CCDC80,MYO9A,NCAM1,NEFM,NFIA,NNAT,PDE1A,PDE3A,PDGFRA,PCDH18,PRRX1,FAT3,PRKCB,SYTL2,LAMA1,PTN,PTPN13,TMEM255A,ZCWPW1,ZFHX4,ROBO1,ROBO2,TMEM206,GLDN,LGR4,HUNK,SCN2A,RASA3,DOCK10,ST8SIA1,PKNOX2,PALLD,ZCCHC24,KDM3A,UHRF1BP1L,SMOC1,ST5,ADGRL3,KLHL4,ZFPM2,ACTR6,ASXL3,DAAM2,TNNT1,TRPS1,TMEFF2,FLRT2,PLEKHH2,PCDH20,LYPD6,WNK3,DPF3,ST8SIA2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.65E-09 8.44E-06 1.59E-08 1.45E-07 17 23 "VAT1L,INA,CHGB,SYT17,GFRA2,STMN2,LIX1,L1CAM,NELL2,SLC10A4,PROX1,RGS4,SCG5,SYT11,SYT1,UCHL1,STMN4" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_100 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_100 FaceBase_ST1 1.71E-09 8.71E-06 1.64E-08 1.50E-07 34 73 "ERMN,PCDH19,TAOK1,ASCL1,INA,JAM2,LHX2,RAB33A,FEZ1,CNTNAP2,SCRN1,JAKMIP2,ELAVL3,FABP7,EFCAB2,GLDC,UBE2QL1,HES5,TUBB2B,LMO1,MT3,SCG3,LYRM9,PAK3,PAX6,MINDY2,LINC00461,HSPA4L,KIF21A,SOX2,NPAS3,NR2E1,FAM181B,XRCC4" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_200_k2 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.86E-09 9.47E-06 1.78E-08 1.62E-07 46 116 "GALNT13,RNF150,C1QTNF3,ALCAM,DPP10,DOCK11,IL33,LDB2,MYOM2,RASSF2,NTM,CALN1,EBF1,EDN3,SEMA3D,TMTC1,GABRA1,IQGAP2,GGT5,GLRB,GRIA1,GRIA4,GRM3,GUCY1B1,WIF1,RASSF8,IFI16,KCND2,NOVA1,DDR2,RELN,FAT4,CSRNP3,SCN3A,LRRTM4,SCN7A,FAM19A1,DOCK10,ST8SIA1,SLCO1A2,NEK4,PCDHB9,TLR4,TTPA,PCDH20,SOCS4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.94E-09 9.88E-06 1.85E-08 1.69E-07 65 191 "ABAT,FMNL2,KLHL13,NR0B1,KCNT1,PPP4R4,IGDCC4,NUMB,ATP2B3,WASF1,CACNB2,CALB1,SLC16A4,DCLK1,MAGI1,CHRM4,AKAP5,PLXNA4,CTH,DOCK4,DAPK1,CDON,DRP2,RASGRP1,KLHL5,EMX2,NRN1,IP6K2,GABRA4,TRAF3IP2,PCDH11X,KCND2,KLHL23,MAP2,MATN2,KITLG,SESN3,CCDC80,MYO9A,NFIA,PPP3CC,PTPN13,REV3L,ZFHX4,LGR4,HUNK,TNFRSF19,RASA3,ZFP30,ST8SIA1,SLC4A3,SCMH1,SOX5,KDM3A,UHRF1BP1L,SMOC1,ST5,ADGRL3,ZFPM2,ACTR6,KAT6B,TNNT1,FNDC5,ZNF23,NAV2" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.98E-09 1.01E-05 1.89E-08 1.72E-07 141 533 "ABCF1,ADCYAP1R1,KIAA1324,DISP3,TAOK1,CEP126,PARG,EPB41L5,USP37,ATM,DOCK11,ZNF599,PROM1,KSR1,PTBP2,MAP7,CDH2,CFL2,JAM2,PLAA,NMT2,NIPBL,CNTFR,SLC4A7,AHCTF1,IGDCC3,FAM169A,CTNND2,KATNAL2,JAKMIP2,ZEB2,DDX46,POM121,SMG7,CASP8AP2,PHF20L1,ABI2,PLXNC1,EIF4G2,EIF5,PAN3,PLEKHO1,EPB41,LRRC23,CEP85L,ACSL4,FGF12,FHL1,ZCCHC17,SMC2,USP16,FAM49B,ATP2C1,FUT9,B3GAT1,MPP6,PHYHIPL,ILDR2,KIAA1841,BRD8,TCERG1,GLDC,DBF4,ZNF638,MAP7D2,FERMT2,PCLO,CIT,MFSD2A,SOX21,PSIP1,USP51,LRRTM1,KIT,KTN1,TM6SF1,MIA2,SCG3,NASP,NOVA1,NTRK2,ODF2,OPA1,PAX6,PDE3B,FAM98B,SEMA5B,ANLN,PLP1,SLC25A23,POLG,MAPK8,VPS13C,SLC22A23,ELOVL2,PTK2,SPDL1,EML5,CCDC40,RBBP8,RFX3,RFX4,SAFB,SFPQ,KIF21A,MAGI3,FHOD3,PREX2,PPP4R3A,SLCO1A2,INTS9,BDP1,SPTAN1,LMO3,LARP4,NEK4,KANK1,PRRC2C,SYN1,ANKRD28,ZNF106,TJP1,LRRC8A,TPM3,TPM4,PRMT8,PDSS1,TTC3,FLRT1,USP1,RBFOX3,XRCC4,KCNT2,REEP1,EML6,SPIRE1,SMARCAD1,PDSS2,MRPL47,RTN4,FXR1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.01E-09 1.03E-05 1.92E-08 1.75E-07 47 120 "SLC12A5,PCDH10,THSD7A,RUNX1T1,CDH2,DCLK1,CLGN,SLC35F1,TENM4,SIPA1L1,ERC2,GPSM1,NTM,EDNRA,EPHA5,ETV1,EYA1,TMEM132C,FOXF2,SGIP1,DACH2,MEGF10,GABRB1,AGBL5,IFI16,LRRTM3,KCNA6,MARK1,GPR85,SSH1,HMGCLL1,PTPRG,PTPRZ1,FAT4,ZFHX4,NTNG1,ANKRD6,SLC15A2,SOX11,NPAS3,FBXL16,ASXL3,ZFP91,KAT6B,RPRM,FMN2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K4 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.33E-09 1.19E-05 2.22E-08 2.02E-07 32 67 "LTBP4,GPRASP2,ASCL1,BMPR1B,SRSF11,LHX2,CREB5,FEZ1,TOX,EMX2,EPHA5,FOXG1,ACSS1,GATM,PPARGC1A,GRIK2,RABL2A,CCDC80,NCAM2,NELL2,NFIA,PCDH9,FEZF2,RTN1,SALL1,NTNG1,MAST1,FAM189A1,NR2E1,FMN2,LRP8,SENP7" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K2 Gudmap RNAseq 2.65E-09 1.35E-05 2.52E-08 2.30E-07 40 95 "KIAA1324,EPB41L5,KIF1A,CAMK2A,MAP7,JAM2,ARHGAP22,NRXN3,IQCK,IGDCC3,FEZ1,CTNND2,ELAVL2,ELAVL4,ADGRV1,FABP7,TUBB4A,FUT9,GLDC,GPM6A,RNF165,CELF3,TOX2,FRMD5,KCNK1,MAP6,MSI1,NRCAM,PLTP,MAPK4,GDPD2,ELOVL2,NKAIN1,RTN1,HSPA4L,SCG5,SLIT1,ANKFN1,BEX1,DPYSL5" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.89E-09 1.48E-05 2.74E-08 2.50E-07 119 432 "ABAT,KDM5D,FMNL2,HECW2,NR0B1,KCNT1,SEMA7A,GAS7,LGR5,PPP4R4,CADPS,NUMB,DDX3Y,ATP2B3,ALDH7A1,DST,ST3GAL5,CALB1,RGN,SLC16A4,CDH10,DCLK1,MAGI1,CDO1,ADGRG1,QKI,VCAN,PLXNA4,CTNND1,DOCK4,DAPK1,SCRN1,DCT,CDON,DRP2,DTNB,RASGRP1,SIDT2,MRO,PLXNC1,SORBS3,TMEM35A,EMX2,MTSS1L,EPS8,NRN1,FAM198B,PTK2B,CAMKK2,GABRA4,GABRB1,BRPF3,GATM,PPARGC1A,PCDH11X,GPR37,PACSIN2,LRRTM3,KCNH1,KLHL23,KCNK2,MATN2,KITLG,AFF1,MSI1,MYO9A,NFIA,NUCB2,PAK3,PDGFRA,ABCB1,SERPINE2,SERPINI1,PIK3C2A,PPP2R5C,PPP3CC,RASGEF1B,PRKCB,MDGA2,RBBP8,REV3L,RNASE1,ZFHX4,ROBO1,TMEM206,RPS6KA2,LGR4,HUNK,TNFRSF19,SOX6,MRAS,DOCK10,ST6GAL1,ST8SIA1,SLC4A3,SNCA,SOX5,UHRF1BP1L,SPP1,SMOC1,LRRC4,ST5,FGD4,ADGRL3,OBSL1,TEX15,DNAH7,ZFPM2,HEY1,ACTR6,FNDC5,TST,PCDH20,ZNF23,SPIRE1,SLC38A1,ADAMTS9,WNK3,DPF3" Coexpression Atlas ratio_SC_vs_DE_1000_K4 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 2.98E-09 1.52E-05 2.82E-08 2.57E-07 102 354 "TTYH1,SYN3,UNC5A,VAT1L,SYT6,VSTM2A,CHGA,CHRNA4,CHRNB2,SLC24A2,CNTN1,ANKRD35,HS3ST5,C1QL2,GALNT9,RIMS4,SEC14L5,TOX,PHYHIP,JAKMIP2,TMEM130,PARD6A,CACNG7,AASS,LINC00599,SEZ6,ANKRD13B,PIPOX,CEND1,OLFM1,ACTL6B,HPCAL4,NSG1,JPH4,IGSF5,TTBK1,RND1,TOX3,PCDH11X,GRIA4,GRIN1,SOX21,LINGO1,WIF1,NXPH2,HRH3,LRRC75A,BTBD17,RIPPLY2,LRRTM3,KCNN2,KCNN3,KIF5A,FGFBP3,MMP16,MMP17,CPNE9,MYCN,FXYD7,NELL2,VWA2,NOVA2,NPTX2,NTRK3,ZDHHC22,PAH,NLGN3,CAMKV,PLP1,PCDH18,EPB41L4B,POU3F4,NKAIN4,RAB39A,PRKCG,GDPD2,PTPRZ1,TMEM145,RYR1,IL17RB,SCG5,SLITRK3,BCAN,LRRC55,TRERF1,KIF21B,LMO3,SOX21-AS1,SEPT3,RHBDL3,ARHGEF9,ARC,SYP,TAC1,TAC3,TACR1,ACSL6,TMEM151B,TTPA,VSNL1,TSPAN11,CRB2" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_1000 dev gonad_e13.5_M_DevVasTestis_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.06E-09 1.56E-05 2.89E-08 2.64E-07 204 846 "ACLY,AS3MT,NCKAP5,GRAMD1B,ADORA2A,HECW2,NR0B1,ADGRF5,SPARCL1,SEMA6A,LTBP4,BIN1,SEMA7A,MAP4K3,APBB2,GPAM,APOC1,SHROOM2,DDX3Y,ATP1A3,ATP1B3,DOCK11,NRP2,ARHGEF7,C1QC,CACNB2,CBLN1,LDB2,FMNL3,SCARB1,CD38,CD81,LGI1,DLGAP1,MS4A7,JAM2,RAB33A,CLU,FADS2,ABCG2,MAP4K4,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,LRRC3B,PPP1R16B,USP6NL,CX3CR1,CYBB,DOCK4,TCAF1,TOX,RASSF2,GIT2,PITPNC1,ARMCX2,ZEB2,ELMO1,CPEB2,ABCC9,EBF1,EDN1,EDNRA,EDNRB,HEYL,PHF20L1,EGFR,PLXNC1,LPAR6,PLEKHA1,CALCRL,RASGRP2,DENND4A,IGSF6,NRN1,FAM198B,ACSL4,CORO2B,DLC1,FDFT1,TMEM164,FLT1,AFF2,UFM1,PDLIM5,FYB1,FYN,IQGAP2,GAP43,GATM,ALDH1L1,FREM1,PCDH17,GGTA1P,HPGDS,MSL3,LILRB4,GPM6A,GPM6B,LPAR4,RAPGEF4,GRB10,GRIA2,GUCY1A1,MAP4K5,MAEL,NCKAP1L,ELOVL5,HMGCR,ZDHHC15,ICA1,ITPKB,KCNH1,KCNJ3,KLHL23,KIT,INSYN2,LIFR,LMO2,LSS,PIK3AP1,TM6SF1,MEF2C,MEST,MSR1,LAYN,MYO6,NPY,OPHN1,PAK3,PCDH9,PDE1A,PDE2A,PDE4B,PDGFRA,ABCB1,PLCL1,PLIN1,FXYD1,PLTP,SPATA6,FAT3,MINDY2,RASGEF1B,MASP1,LAMA1,SNRK,MDGA2,PTK2,STK32A,PTPRB,TMEM255A,C1orf54,SLC6A15,RGS10,ROBO1,ROBO2,SEMA6D,RASA3,SGK1,PPM1E,SLA,PREX2,BTBD3,SMTN,SLC15A2,EFHD1,CPEB4,LIMCH1,PEG10,COLGALT2,THSD1,SMOC1,ACSBG1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,TEK,TF,ZFPM2,TGFBR3,HHIP,TIE1,HEY1,TJP1,HEY2,TRPC3,RFTN2,VSNL1,WIPF1,ZNF711,STOX2,NAV3,PLD4,FAM13C,DOCK8,ZDHHC20,DPF3,RNF146,SPATA13" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_1000 dev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.39E-09 1.73E-05 3.20E-08 2.91E-07 204 847 "NCKAP5,CCDC85A,GRAMD1B,ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,BIN1,ANK2,SEMA7A,LCORL,MAP4K3,APAF1,APBB2,APOC1,SHROOM2,ARRB1,DDX3Y,ATP1B3,DOCK11,ADAM15,BACH1,NRP2,PROM1,ARHGEF7,C1QC,THSD7A,SPAG9,CBLN1,LDB2,FMNL3,SCARB1,CD38,LRRFIP1,JAM2,CLU,ABCG2,TMEM184B,MAP4K4,LY86,ZNF521,CDC42BPB,CREB5,CRMP1,HAPLN1,ABCG1,CSF1R,LRRC3B,PPP1R16B,USP6NL,CX3CR1,CYBB,DOCK4,TOX,RASSF2,GIT2,DBN1,ARMCX4,PITPNC1,ARMCX2,ELMO1,SACS,FAM107B,GNE,EBF1,EDNRB,SH3GLB1,MBNL2,PLXNC1,LPAR6,PLEKHA1,CALCRL,PLEKHO1,RASGRP2,STX2,DENND4A,FAM198B,CORO2B,DLC1,CHST15,KIAA1109,TMEM164,FLT1,UFM1,PDLIM5,TRIM16,FYB1,FYN,NEK6,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,GPM6A,LPAR4,RAPGEF4,STMN2,GRB10,GRIA2,MAP4K5,NCKAP1L,KLF12,ZDHHC15,ICA1,IGF1,ITPKB,KIT,INSYN2,LMO2,SMAD1,TM6SF1,MEF2C,MEST,KITLG,MID1,LAYN,MYO6,CLEC9A,OPHN1,PAK3,PALM,PDE2A,PDE4B,PDE4D,GNG2,PFKP,ABCB1,PLCL1,PLTP,SPATA6,RASGEF1B,MASP1,SYTL2,SNRK,MDGA2,PTK2,PTPRB,RIPOR1,TMEM255A,C1orf54,RGS3,ROBO1,ROBO2,PRR5L,RPS6KA2,SEMA6D,RASA3,SGK1,FAM102A,MYO18A,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,UNC5B,PEG10,ITPRID2,SAMSN1,THSD1,SMOC1,RGL1,ADHFE1,ACSBG1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,ZEB1,DOCK9,FRYL,TEK,TF,C18orf54,TGFBR3,HHIP,TIE1,HEY1,TJP1,TLR4,HEY2,TPM4,TRO,TRPC3,DCBLD1,RFTN2,VSNL1,WIPF1,ZNF711,GDPD5,STOX2,ADAMTS9,NAV3,FAM13C,DOCK8,ST7,NHSL1,ZDHHC20,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 3.64E-09 1.86E-05 3.43E-08 3.12E-07 131 490 "ACTN2,ERMN,SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ZFYVE28,ATP1A3,ATP2B2,KIF1A,TTLL9,BARD1,NRP2,ZNF599,IL33,CA12,CACNA1B,CAMK2A,CAMK2B,INA,REPS2,KCNAB3,SRSF11,NRXN2,CLU,SLC24A2,IGDCC3,CREM,CRYBB1,CRYM,MICAL2,PLCH2,PHF14,ST18,SCRN1,DLG2,ST8SIA3,SNX29,ELAVL3,RASGRP2,SEZ6,NCALD,CDKL3,ADGRV1,CLVS1,PTK2B,CORO2B,HPCAL4,ZMYND15,SEMA4D,DLL3,FUT9,ADGRA1,ABLIM2,FYB1,GAD1,ARPP21,SRRM4,PPARGC1A,LYVE1,NTNG2,ADAP1,GRK4,PCLO,GRIA1,GRIK2,TMEM25,CELF3,HPSE2,SMAP1,ATCAY,KNDC1,IGSF1,SCIN,HES5,LIX1,INSM1,ZNF385B,ITGAV,KCNA6,HECTD2,GPR155,MID1,MITF,MOBP,CPNE9,BCO1,RSPO2,MYH3,MYT1,CLEC9A,ETFRF1,PDE4D,ENPP2,GDAP1L1,NXPH1,PRKAR1B,MAPK10,DIRAS2,MASP1,GDPD2,STRC,VEPH1,ZMAT4,DUSP15,REV3L,KCNIP3,SH3GL2,CCDC92,SLC1A2,CCDC88A,SLCO1A2,INAVA,C11orf87,SAMSN1,ACSBG1,LEFTY2,ASXL3,TMOD1,STXBP4,RBFOX3,LAMP5,CADM2,STMN4,PCDH15,DNAH10,PRRT4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Subtype_hRgl2b_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.71E-09 1.89E-05 3.48E-08 3.18E-07 32 68 "TTYH1,NDRG2,SPARCL1,ATP1A2,PRC1,NCAN,SDC3,LYPD1,OLIG1,EDNRB,EGFR,TNK2,OLIG2,FABP7,C1orf61,GFAP,DCLK2,GPM6B,SCRG1,HES5,FGFBP3,NFIA,NFIX,NTRK2,PMP2,PTN,PTPRZ1,BCAN,SLC1A3,INKA2,WSCD1,CABIN1" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000_k5 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.83E-09 1.95E-05 3.59E-08 3.27E-07 91 306 "SLITRK1,AXIN2,SORCS1,BCAR3,SYT13,FGD2,PDE8B,PROM1,BMP7,BMPR1B,CACNA1B,CACNA1D,CALB1,MTMR7,MAGI1,CRLF1,CBARP,B4GALT6,SLIT2,KIAA1549L,TMEM59L,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,FAM169A,CTNND2,RIMS2,TOX,AIF1L,DUSP9,EMX2,ACSL4,SPSB4,FGF12,SEMA4D,RASL10A,GFRA1,TOX3,MAP7D2,GRIK1,GRIK2,MFSD2A,PADI2,FRMD5,L1CAM,MBP,KITLG,LYRM9,MYH7,VWA2,NRCAM,CDK18,SEMA5B,PLCL1,SLC25A23,GDPD1,LAMA1,EML5,PTPRZ1,FAM184A,SUSD4,RASGRF2,RET,SGSM1,SOX8,SCN2B,SCN4B,SOX6,SCG5,SH3GL2,FHOD3,INAVA,RAP1GAP2,LRRC4,SYT11,NUDT10,TMEM150C,UNC5D,WSCD1,TCF7,PRMT8,DCBLD1,RPRM,UCHL1,SLAIN1,LMF1,VSNL1,FSTL5,DPYSL5,DOCK8" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k4 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.06E-09 2.07E-05 3.80E-08 3.46E-07 88 293 "ABAT,RNF150,FAM135A,AMPH,APAF1,EPB41L5,VAT1L,BLM,BMP7,FUBP1,IL33,ZFP28,CLOCK,SNCAIP,VCAN,RIMS2,ARHGAP32,SCRN1,RAB39B,DTNA,HEYL,ASB3,CDHR1,EYA1,ATP8A1,ST3GAL6,MED12L,UBE2E3,FAM49B,KIAA1841,FREM1,BRD8,PARD3B,GRM3,PTPRT,FRMD3,IFI16,KCNA1,LIG4,TM6SF1,MYO5A,NCAM1,NELL1,NPTX1,DDR2,OPA1,OXTR,CNTN3,PRTG,EPDR1,PIGG,FAM184A,GAL3ST4,TTLL7,KIRREL1,PRR5L,SALL1,CSRNP3,PPM1E,DOCK10,ST8SIA1,ANKRD6,EFHD1,CXXC4,CMTR2,FNBP1,SOX11,KIF1B,C11orf87,CLSTN2,NEK4,ANKRD28,CAMTA1,ACSL6,PCDHB9,PCDHB3,ARHGEF12,HEY1,ASXL3,RGMB,SLAIN1,ZFAND5,C12orf4,FZD3,CERS6,NETO2,SOCS4,SENP7" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.11E-09 2.10E-05 3.84E-08 3.50E-07 38 89 "TAOK1,DPP10,CADPS,CACNA1B,CACNA2D1,CDH10,CHGB,PLCXD3,GRIN3A,ELAVL2,ELAVL4,EPHA5,DLC1,FOXF2,DACH2,DNER,GFRA1,STMN2,IFI16,KIF5C,MAP4,RSPO2,NEFM,CLDN11,NALCN,PRRX1,MAPK10,PRPH,RGS4,ZFHX4,RTN1,SCN3A,SNAP25,SCN3B,SOX2,C11orf87,RBFOX2,RGMB" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.24E-09 2.16E-05 3.95E-08 3.60E-07 98 338 "ADCY2,RNF157,ADCYAP1R1,WDR35,ARHGAP20,GPAM,LRRC4C,CASK,MPDZ,CACNA1G,MYRF,CACNA2D1,KALRN,CBLN1,CDH10,LARGE1,SLIT2,CNTFR,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,ZEB2,HEPH,ALKBH8,SV2A,SRGAP3,DNM1,TSPAN5,EDNRA,SEMA3D,LRRC17,FABP7,EFEMP1,FGFR1,MEX3B,CAP2,FLNC,ST6GALNAC3,NSG1,DENND2A,FREM1,GHR,GLI2,B4GALNT4,GUCY1A2,GUCY1A1,GUCY1B1,TCEAL6,NKD1,MATN2,MEIS1,MEIS2,MMP16,NCAM1,NEFM,NFIA,NNAT,NME4,PDE3A,PDGFRA,PIK3R1,PCDH18,PRRX1,FAT3,SH3KBP1,SYTL2,LAMA1,PTN,ZIK1,PTPRD,PTX3,ROBO2,ZNF354C,SATB1,SCN2A,ZNF821,DZIP1,PKNOX2,ARFGAP1,SMARCE1,PALLD,ZCCHC24,CAND2,SULF2,SEPT3,KLHL7,PSD3,TGFBR3,ASXL3,TPM1,STXBP4,TRPS1,TMEFF2,AMOT,PLEKHH2,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_1000_J DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.24E-09 2.16E-05 3.95E-08 3.60E-07 189 774 "SERPINA3,NDRG2,ADCY5,PLEKHH1,USP31,ADGRF5,SPARCL1,ANK1,PI16,APC,VAT1L,ATP2A2,ATP6V0A1,MYOM1,ADAM23,NRP2,DST,CACNA1B,CACNA2D1,CACNB4,CAMK2D,CAST,ENTPD2,MYOM2,REPS2,LRRFIP1,CFL2,CHGB,RAB3C,CLCN3,CNR1,CNTN1,AKAP5,ABI3BP,MFSD4A,GDA,OSBPL3,CNTNAP2,KIAA0040,CTNND2,MYADM,DNAJC6,MFAP3L,TMEM130,SPOCK3,RABGAP1L,CHRDL1,DMPK,DNM2,CPEB2,DTNA,ABCC5,ABCC9,HIPK3,SH3GLB1,ELN,CALCRL,EPS8,MRVI1,NRN1,ACSL4,TUBB3,EFEMP1,DLC1,PRKAG2,FHL1,CAP2,FOXF2,FLNC,SORBS1,PDLIM5,TRIM16,DACH2,FUT9,SDCBP2,DKK3,CHL1,GALNT15,ILDR2,DNER,IGSF5,GCNT2,LYVE1,GNG4,FERMT2,PRUNE2,STMN2,TPPP,GSN,BVES,WIF1,IFI16,IL6ST,SLC35G1,KCND3,KCNK1,KCNMA1,KIF5A,KIF5C,MAP4,MBP,IL17D,MYH3,MYH7,NEFM,NFIA,NFE2L2,NPTX2,DDR2,PDE4B,PDE4D,PIRT,PFKP,PIK3C2A,SCHIP1,PRRX1,FA2H,KANSL1,PRKCB,MAPK10,PRPH,SLC22A23,SYTL2,PTHLH,RET,REV3L,RGS4,TTLL7,ZFHX4,RTN1,RYR3,SCN2A,SCN3A,SCN7A,STUM,SH3BGR,SH3GL2,FHOD3,SMTN,LIMS2,SLC14A1,RIMS1,SNAP25,SCN3B,SOX2,TNIK,FNBP1,ZHX3,MYCBP2,DBNDD2,RAP1GAP2,C11orf87,ATP10B,CLASP2,EPB41L3,NACAD,SYN2,COBL,POPDC3,TACC1,SEMA4A,CAMSAP2,PCDHB7,TF,TGFBR3,ZNF106,HHIP,SLC44A1,ENHO,TLR4,ERCC6L2,TNNT1,TNS1,RBFOX2,RASD2,TPM1,TPM2,SYNPO2,PPIL6,UCHL1,TBC1D15,RBFOX3,AGMO,ZBTB16,FSTL5,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_k2_1000 kidney_adult_Mesangium_Meis_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.95E-09 2.53E-05 4.60E-08 4.19E-07 100 348 "CPNE2,ACHE,ADCY6,ESYT2,APBB2,PDE8B,DDX3Y,CACNA2D1,CHN1,NRXN3,ARHGEF6,SLC4A7,CP,PNKD,FEZ2,KIAA0040,USP6NL,HDAC9,TOX,DGKB,ARMCX4,ZNF804A,ZEB2,ABCC9,EBF1,FRY,FSD1L,EPB41L2,RCAN2,LRRC17,RASGRP2,ETV1,RASL12,MRVI1,TAOK3,DLC1,CHST15,FER,NBEA,SPECC1,ATP2C1,KHDRBS3,TVP23A,HIGD1B,GNAO1,ATE1,GUCY1A2,GUCY1A1,GUCY1B1,FRMD3,KLF12,INPP5B,JAK2,HECTD2,MARK1,SHC3,MEF2C,MMP16,ADAM22,N6AMT1,NCF2,NTRK2,PDE3A,ABCB1,SERPINE2,SERPINI1,PIK3R1,PLCL1,FXYD1,PCDH18,SEPT4,SH3KBP1,PRKAB2,PTN,PYGM,ZMAT4,RGS4,ROBO1,DOCK10,PREX2,SLC12A2,ZCCHC24,UNC5B,ITPRID2,MPRIP,TACC1,ADGRL3,TMEM136,ZEB1,PSD3,GPRIN3,TNS1,TRPC1,RFTN2,TMEFF2,ZBTB38,ZFAND5,FAM13C,PHTF2,CPNE4" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.09E-09 2.60E-05 4.72E-08 4.30E-07 37 86 "ADCY2,OSBPL6,PCDH10,CADPS,CACNA2D1,NRXN3,LY86,CNTN1,CNRIP1,VCAN,ZEB2,EPB41L2,NCALD,MRVI1,DACH2,DKK3,GRM7,GUCY1A1,NEGR1,KCND3,MMP16,CCDC80,CLDN11,PENK,PRRX1,NKAIN4,PTX3,LRFN5,SCN7A,CXXC4,PDLIM2,ANO4,VWC2,SYNPO2,TMEFF2,PROCA1,NAV3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500 FaceBase_RNAseq 5.11E-09 2.61E-05 4.73E-08 4.31E-07 129 483 "EMILIN3,NCKAP5,ACTN2,NDRG2,ADCY2,ARHGAP20,LTBP4,GPRASP2,CDK10,ASTN1,TTLL9,ADGRB2,BARD1,C1QC,CACNA1G,LDLRAD4,CACNA2D1,CAMK2A,SLC25A14,REPS2,LONRF2,KCNAB3,CDO1,CRLF1,SRSF11,NRXN3,PPT2,KIAA1549L,CNTFR,CREB5,ANKRD44,CSF1R,FEZ1,ST18,ARHGAP24,TOX,SPOCK2,SV2A,CCDC3,DLG2,DMD,SHANK1,SEMA3D,EGFR,ELN,TMEM35A,LRRC17,EPHA5,CHST15,FCGRT,FGF11,TRIM16,NRG3,FYB1,JPH4,TMEM8B,PCDH17,PPARGC1A,ZNF276,PCDH11X,GRIA1,NR3C1,GSN,MFSD2A,WIF1,SYNPO,IL11RA,ZNF385B,METTL21A,KLHL23,VWA5A,SRSF12,CD200,CCDC80,RSPO2,NEXMIF,TCEAL5,NCAM2,NELL2,NFIA,NFIX,NRGN,OGG1,CNTN3,PCDH9,PDE1A,PLCL1,PMP22,SDK2,MAGEL2,POU6F1,PRODH,MASP1,DEF8,MDGA2,ZMAT4,BAALC,PRR5L,EMID1,DGLUCY,ATXN1,FERMT1,DOCK10,NTNG1,NLGN1,SLC1A2,NPAS3,CLSTN2,ZFR2,SEMA4A,ADGRL3,ACSL6,SATB2,AZIN2,PHF24,FAM189A1,TMEM121,SYNPO2,KCNE5,FLRT1,TSPAN11,FMN2,EML6,PMEPA1,CADM2,PCDH15,NAV3,DPF3,SENP7" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_500 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.21E-09 2.66E-05 4.81E-08 4.38E-07 116 422 "ABAT,FMNL2,ADD3,AXIN2,MTA3,KLHL13,NR0B1,ARHGAP20,OGT,SEMA7A,APOC1,SHTN1,LGR5,CDC14B,SEMA4G,PPP4R4,PDE8B,CAPRIN2,INSYN2B,ATP2B3,RNF182,BCHE,CACNA1D,CACNB2,CALB1,SLC16A4,REPS2,DCLK1,MAGI1,ADGRG1,CHRM4,CLU,NMT2,PLXNA4,BOC,DOCK4,DAPK1,MAGI2,SRGAP3,DOCK2,DRP2,RASGRP1,OPTN,MRO,EMX2,EPB41L1,NRN1,AFF2,NSG1,ZMAT1,GABRA4,GABRB1,GALC,GATM,SESN1,GRIK3,TCEAL6,SHISA6,PLD5,DIPK1A,SLC35G1,KCND2,KLHL23,MAP2,KITLG,SESN3,MTR,LAYN,MYO9A,NEXMIF,NFIA,NPR2,PDE1A,ENPP2,CDK14,SERPINI1,PCDH18,PPP2R5C,MAPK9,GDPD1,GDPD2,CNTLN,RNASEL,ZFHX4,TMEM206,MEG3,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,SLC4A3,TNIK,KDM3A,UHRF1BP1L,ARHGAP26,TSPYL2,SMOC1,ST5,ADAMTS17,ADGRL3,TCF12,TEX15,ACTR6,DAAM2,TNNT1,FNDC5,DCBLD1,TST,VSNL1,ZNF23,ELFN1,LYPD6,TMEM178A,WNK3,FRMD6" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_1000 kidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.51E-09 2.81E-05 5.08E-08 4.63E-07 208 872 "CPNE2,ACHE,NDRG2,ADCY6,ESYT2,OSBPL8,C1QTNF1,SPARCL1,BCAR3,CDC42BPA,MAP4K3,PPFIA2,APBB2,APP,ARRB1,PDE8B,DDX3Y,MYOM1,NRP2,CFLAR,CACNA2D1,CAMK2D,CAST,FMNL3,CD81,UBE2L6,CHN1,NRXN3,ARHGEF6,SLC4A7,CP,PNKD,CLOCK,ANKRD44,CSF1,FEZ2,CST3,SDC3,KIAA0040,USP6NL,HDAC9,TOX,DGKB,ARMCX4,PITPNC1,ZNF804A,ZEB2,FAM107B,DMD,NR1D2,ECM2,ABCC9,EBF1,EDNRA,FRY,FSD1L,MBNL2,EML1,CALCRL,EPB41L2,RCAN2,LRRC17,RASGRP2,EPS8,CEP85L,ETV1,RASL12,MRVI1,TAOK3,DLC1,ST3GAL6,CHST15,FCGRT,FER,KIAA1109,FHL1,POLK,FLT1,NBEA,SORBS1,SPECC1,NPTN,ATP2C1,KHDRBS3,TVP23A,HIGD1B,ERAP1,GGT5,GNAO1,FERMT2,RAPGEF4,NR3C1,ATE1,GUCY1A2,GUCY1A1,GUCY1B1,RASSF8,ZHX1,FRMD3,KLF12,HLF,IFI16,IL6ST,INPP5B,JAK2,KCND3,LIFR,VWA5A,HECTD2,GPR155,MAPT,MARK1,SHC3,MEF2C,MMP16,CCDC80,ADAM22,N6AMT1,LAYN,NCF2,IDNK,NFIX,NTRK2,DDR2,PDE1A,PDE3A,PDGFRA,ABCB1,SERPINE2,SERPINI1,PIK3R1,CCSER2,PLCL1,FXYD1,PCDH18,SEPT4,SH3KBP1,MINDY2,PRKAB2,PKIA,SNRK,PTH1R,PTN,PTPN13,PTPRB,PYGM,FAM184A,ZDHHC14,ZMAT4,FIGN,RGS4,RERGL,ROBO1,LRRK2,WLS,ATXN1,SGK1,DOCK10,PREX2,EPN2,SMTN,SLC8A1,SLC12A2,CPEB4,LMBRD1,ZCCHC24,UNC5B,ARHGAP26,SPTAN1,ITPRID2,MPRIP,RGL1,STXBP1,TACC1,ANKRD12,FAM208A,ADGRL3,TMEM136,ZEB1,SYNE1,PSD3,ARHGEF12,TNS2,GPRIN3,FRYL,CYB561A3,TEK,TF,C18orf54,TGFBR3,TJP1,TLR4,DAAM2,TNS1,TPM2,TRPC1,RFTN2,TMEFF2,PLEKHH2,VLDLR,ZBTB38,SPIRE1,ZFAND5,PLSCR4,FAM13C,DOCK8,PHTF2,CPNE4" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 5.76E-09 2.94E-05 5.31E-08 4.84E-07 67 204 "ABCF1,ADCYAP1R1,KIAA1324,DISP3,TAOK1,EPB41L5,ATM,ZNF599,PROM1,JAM2,CNTFR,SLC4A7,IGDCC3,FAM169A,CTNND2,KATNAL2,JAKMIP2,DDX46,PLXNC1,CERCAM,LRRC23,ACSL4,FGF12,FHL1,FUT9,B3GAT1,PHYHIPL,ILDR2,TCERG1,GLDC,MAP7D2,PCLO,CIT,MFSD2A,SOX21,USP51,LRRTM1,KIT,KTN1,TM6SF1,SCG3,NASP,NOVA1,NTRK2,ODF2,FAM98B,SEMA5B,PLP1,SLC25A23,SLC22A23,ELOVL2,EML5,CCDC40,RFX4,KIF21A,FHOD3,SLCO1A2,BDP1,LMO3,NEK4,SYN1,ANKRD28,ZNF106,PRMT8,RBFOX3,KCNT2,FXR1" Coexpression Atlas GSM399454_500 "Stem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3" "Immgen.org, GSE15907" 6.03E-09 3.08E-05 5.54E-08 5.05E-07 116 423 "CPNE2,FMNL2,ZNF608,OSBPL1A,ALCAM,CDC42BPA,ALDH7A1,DST,BTK,SGCE,CACNB2,MAP7,UBE2L6,ADGRG1,B4GALT6,NRXN1,FADS2,ABCG2,AKAP7,SLC25A27,MAGED1,ZNF521,GDA,CSF3R,CTNND1,CYBB,GPRASP1,ARHGAP32,LONRF1,DGKG,SIRPA,DNAJC6,EBI3,PLXNC1,CALCRL,EYA1,ARMCX1,MED12L,PRKAG2,FOXO3,ZBED3,GAB1,IQGAP2,GATM,GCNT2,GLUL,ADGRA3,GRB10,GRIK5,PRDM5,GUCY1A1,IRAK3,KLF12,HLF,HP,ICA1,DOCK7,USP54,IL12A,ITGAM,KIT,STXBP5,STMN1,LMO2,MEF2C,MEIS1,MN1,MDGA1,MYCN,LAYN,RCOR2,NFIA,NFIX,NME4,NPR2,OCRL,PBX1,PLCB2,LRRC49,DEF8,PTPRE,RIPOR1,SLC6A15,RNASEL,ZNF532,TCP11L1,PLPPR3,ATAT1,FOXRED2,PEAR1,ITSN1,PPP1R9A,ARHGEF40,TET1,CABCOCO1,MPRIP,FGD4,SYNE2,ANKRD28,KLHL4,DMXL2,PSD3,ARHGEF12,TEK,TIE1,BHLHB9,TLR4,TNS1,NPL,STXBP4,SSBP2,VIPR2,VLDLR,ZBTB38,PLSCR4,ST7" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500_K5 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 7.01E-09 3.57E-05 6.43E-08 5.86E-07 27 53 "SHTN1,ASCL1,HAP1,ADGRG1,SRSF11,NRXN3,ST18,DTNA,ADGRV1,TUBB3,FOXG1,GAD1,SRRM4,FAM222A,TOX2,IGFBPL1,HES5,KCNH2,MBP,MSI1,NNAT,NRCAM,GAL3ST4,LINC00461,DPYSL5,FZD3,SPATA13" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 7.57E-09 3.86E-05 6.93E-08 6.32E-07 18 27 "VAT1L,CADPS,INA,ELAVL2,EYA1,FABP7,TUBB3,GAP43,IGSF5,STMN2,SCG3,NEFM,RTN1,SCG5,SCN3B,CUX2,TMEFF2,STMN4" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.74E-09 3.95E-05 7.08E-08 6.45E-07 82 270 "FMNL2,KLHL13,NR0B1,KCNT1,LRCH2,CACHD1,PPP4R4,IGDCC4,PDE8B,NUMB,INSYN2B,ATP2B3,WASF1,CACNB2,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,MAGI2,CDON,DRP2,KLHL5,EMX2,EPB41L1,MTSS1L,NRN1,OLFM1,NSG1,GABRA4,GABRB1,PCDH11X,GPD2,IGF1,PLD5,KLHL23,MAOB,KITLG,AFF1,SESN3,MYO9A,NFIA,NOS1,NPR2,NUCB2,PDE1A,CDK14,SERPINI1,GDPD1,GDPD2,CNTLN,PTPRG,FAT4,ZFHX4,LGR4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ZFP30,SLC4A3,SCMH1,KDM3A,UHRF1BP1L,LHPP,ST5,ADGRL3,RPGRIP1L,DNAH7,ACTR6,DAAM2,KAT6B,TNNT1,FNDC5,ZNF23,ELFN1,LYPD6,FRMD6,DPF3" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_1000 kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.95E-09 4.06E-05 7.26E-08 6.61E-07 190 785 "ADCY6,RNF157,ADORA1,KIAA1211,ZNF608,PCDH19,KIAA1324,ALCAM,AMPH,CACHD1,VAT1L,LGR5,TMEM108,BARD1,BCL7A,BLM,PROM1,BMP7,BMPR1B,CACNA1G,CA4,CA12,CACNA2D1,MAP7,PRC1,LRBA,CDH2,CACNA2D2,CHN2,SLIT2,CLU,CNTFR,FAM149A,CLIP3,CRYM,SNCAIP,TENM4,VCAN,KIAA0040,GREB1,USP6NL,ARHGAP24,SCRN1,AIF1L,HEPH,GSDME,SV2B,NTM,ARNT2,KBTBD11,DLG4,DTNA,HEYL,SEMA3D,EMX2,HSD17B14,ERBB4,EYA1,FABP7,ST3GAL6,POLR1B,SPSB4,FGFR1,MAD2L2,FHL1,SCARA3,CAP2,SEMA4D,MTHFD2,STARD10,IGSF5,FAXC,GCNT2,GFRA1,FREM1,C1QL1,PPARGC1A,GLDC,TOX3,MSL3,KDM2B,GNG3,ADGRA3,TDRKH,B4GALNT4,CECR2,PARD3B,FAM107A,GUCY1B1,HAS2,BACH2,ZDHHC15,HP,KCNJ16,KCNK1,KHK,KIF5C,L1CAM,GPR155,CLEC18A,MAT2A,TM6SF1,MID1,POC1B,MSI1,MYCN,MYO6,NCAM1,NELL2,NFIX,NME4,NPY,PALM,CNTN3,PRTG,PDE3B,ENPP2,PENK,CDK14,KCTD15,PLXNB1,PMP22,PRRX1,SDK2,SEPT4,FAT3,MAPK4,LAMA1,SPDL1,PTN,ZIK1,PTPN13,PTPRO,FAM184A,ZCWPW1,DUSP15,RAVER2,ROBO1,TMEM100,GLDN,PRR5L,LGR4,HUNK,CCDC112,SALL1,ASRGL1,SCG5,SH3BGR,KIF21A,SH3GL3,FERMT1,FHOD3,CNKSR2,SLC15A2,TET1,GKAP1,SORCS3,PDZD2,SOX11,BEX1,NUDT10,PLCB1,TMEM150C,TACR1,CAMTA1,TAF9,SATB2,CUX2,TRIM2,PCDHB9,ARHGEF12,HEY1,HEY2,TPD52,TRPS1,CA14,CADM1,UCHL1,SLAIN1,PLEKHH2,VLDLR,NSD2,TRIM9,PLPP4,DPYSL5,SPIRE1,SLC38A1,ADAMTS9,FZD3,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.97E-09 4.07E-05 7.26E-08 6.62E-07 56 160 "EMILIN3,ESYT2,ADRB2,SRPX,ARHGAP20,TNRC6C,CACNA2D1,CHN2,RAB3C,NRXN3,NMT2,CNTN1,COL9A1,AKAP12,ZEB2,PLXNC1,EPHA5,NCALD,ETV1,MRVI1,DACH2,PNMA2,DKK3,MEGF10,GFRA2,RAB40B,GRIA4,CACFD1,NEGR1,KCND3,KCNK2,LAMA2,CHIC1,NCAM1,NDP,NTRK2,CLDN11,PENK,NALCN,PTX3,RASGRF1,LGI2,RYR3,LRFN5,SH3BGR,SH3GL3,PLCB1,ANO4,VWC2,HHIP,SYNPO2,TRPS1,FLRT2,TRIM9,PLSCR4,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k1 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.06E-09 4.11E-05 7.32E-08 6.68E-07 53 148 "ADCY5,ANK1,ATP1A2,ATP2A2,MYOM1,NRP2,CACNA2D1,NGB,CAMK2D,ABI3BP,RABGAP1L,DMD,CPEB2,DTNA,ABCC9,NCALD,MRVI1,FHL1,CAP2,SORBS1,DKK3,IGSF5,GCNT2,PRUNE2,BVES,HNMT,IFI16,IL6ST,KCND3,KCNMA1,MBNL1,NPTX2,DDR2,PDE4D,PRKCB,RYR3,SCN2A,STUM,SH3BGR,FHOD3,LIMS2,RIMS1,FNBP1,DBNDD2,POPDC3,ENHO,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,ADAMTSL3,MSRB3" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K2 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 8.36E-09 4.26E-05 7.59E-08 6.91E-07 108 388 "ERMN,PLEKHH1,NLGN4X,MTA3,ZNF608,WDR35,DISP3,SEMA6A,UNC79,FAM135A,SYT13,ZNF687,PDZD4,DPP10,USP28,EPB41L5,CACHD1,VAT1L,SHTN1,SEMA4G,PRX,PPP4R4,IGDCC4,STK33,ZBTB10,RASL11B,TMEM108,CCDC181,MTMR9,PTBP2,PLEKHB1,DLGAP3,FAM19A5,KATNAL2,AIF1L,FAM57B,DPP6,CACNG7,SALL3,DHX35,SHISA6,CELF5,BTBD17,GDAP1L1,CAMKV,FA2H,POU3F4,FSD1,NKAIN1,ACSS3,FAM184A,KHDRBS2,ZMAT4,FIGN,SEC61A2,RIC8B,NUDT11,RPRD1A,LGI2,ZNF532,SETD5,PNMA8A,ZC3H14,LGR4,ZNF331,SEMA6D,CSRNP3,LRRTM4,IL17RB,TRIM46,ZNF821,PPP1R9A,BCAN,PREX2,TMEM132D,TET1,LRRC4,AJAP1,NECAB1,PJA1,SLC19A3,NSD1,KHDC1,CHST8,GALNT17,BHLHB9,TTTY15,CCDC136,SLC13A3,CFAP298,SPHK2,TCEAL7,ANKS1B,SMARCAD1,MEIS3,DHX33,SLC38A1,RGMA,STOX2,SNX27,ITM2C,WNK3,TMEM63C,ACTR3B,VANGL2,NETO1,SLC4A10,JPH3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.65E-09 4.41E-05 7.84E-08 7.14E-07 101 356 "KDM5D,NDRG2,ADCY2,ADCYAP1R1,GRAMD1B,ALCAM,ARHGAP20,LTBP4,AMH,GPAM,DDX3Y,ATP1A3,ADAM23,CACNA1G,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,LDB2,SCARB1,REPS2,SLIT2,CLU,FADS2,CNTFR,MICAL2,VCAN,RIPOR2,ARHGAP24,ARMCX2,ZEB2,CDON,EDNRA,HEYL,EGFR,MRO,PLXNC1,LRRC17,NRN1,FABP7,DLC1,FLNC,AFF2,IQGAP2,GATM,GFRA2,FREM1,GHR,GLI2,PCDH11X,GPM6B,GRIA4,GUCY1A1,GUCY1B1,KCND3,KLHL23,LAMA2,LSS,MATN2,MEIS1,NEXMIF,NCAM1,NFIA,PAK3,PCDH9,PDE1A,PDGFRA,SERPINE2,FXYD1,PCDH18,PLTP,FAT3,LRRN3,RASGEF1B,LAMA1,PTCH1,PTN,TMEM255A,ZCWPW1,SLC6A15,ROBO2,ARMH4,ACER3,MEG3,PKNOX2,SMOC1,SULF2,ACSBG1,ADGRL3,ZFPM2,TGFBR3,HHIP,THRA,TRPS1,TMEFF2,VSNL1,STOX2,ADAMTS9,WNK3,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k1 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.67E-09 4.42E-05 7.84E-08 7.14E-07 38 91 "ADCY2,SPARCL1,IGDCC4,CADPS,RUNX1T1,ELAVL2,CALCRL,GFRA2,GPT2,GPM6B,NEGR1,IGF1,NKD1,KCND2,MATN2,MEIS2,MMP16,FXYD7,NFIX,CLDN11,PDGFRA,PRRX1,PTCH1,LGI2,TMLHE,SATB1,TROVE2,EPB41L3,SYT1,ANO4,EHBP1,VWC2,ZFPM2,HHIP,TNNT1,TPM1,TPM2,TUBB2A" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 8.83E-09 4.50E-05 7.97E-08 7.26E-07 180 736 "ABHD6,EMILIN3,RTL9,SEMA6A,SRPX,MARCH4,ANK1,KCNAB2,APBB2,SLC7A14,CDK10,SEMA4G,IGDCC4,SPTBN4,RASL11B,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDH18,CDO1,CRLF1,UBE2L6,DIS3L,CLTB,COL9A2,COL9A3,ABI3BP,ENTPD4,ANKRD44,CLIP3,SNCAIP,SUSD5,ATRNL1,PYGO1,BOC,DGKG,GSDME,RHOBTB1,CCDC3,GRIN3A,DNM1,USP3,ABCC9,MBNL2,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,DENND4A,ETV1,HSPA12B,FCGRT,FDFT1,TESK2,FECH,SCARA3,SGIP1,SYT3,NBEA,ZBED3,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,TRAF3IP2,ZNF274,CPLX2,NEU3,FREM1,ZNF276,RAB30,GRIK4,WIF1,BACH2,SYNPO,AGBL5,ICA1,IDH3B,IL11RA,INPP1,ITPKB,JAK2,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,CPNE9,MSR1,N6AMT1,RSPO2,MYL3,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE1A,PDE3A,PDE4D,PDGFRA,PFKFB2,CDK14,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,ACSS3,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,RGS10,ZFHX4,MYH14,MRAP2,LRRK2,DGLUCY,ATXN1,SGK1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SMARCC2,IFT122,DOP1A,ZHX3,ARHGAP26,CDK19,COLGALT2,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,TBX15,EHBP1,TCF4,SATB2,ZFP90,SYNE1,PHF24,CRTC1,HIF3A,ASXL3,DAAM2,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF708,ZNF32,FTSJ1,PMEPA1,NAV3,CERS6,SSPN" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K2 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 9.11E-09 4.65E-05 8.21E-08 7.48E-07 164 657 "ABAT,EMILIN3,CCDC85A,RTL9,SEMA6A,SRPX,MARCH4,ANK1,KCNAB2,CACHD1,CDK10,SEMA4G,IGDCC4,SPTBN4,RASL11B,BLM,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,LRBA,CDO1,CRLF1,CLTB,COL9A2,COL9A3,ABI3BP,IGDCC3,ANKRD44,CLIP3,SNCAIP,ATRNL1,PYGO1,BOC,DGKG,RHOBTB1,CCDC3,GRIN3A,DNM1,USP3,DUSP9,ABCC9,MBNL2,ELN,HSD17B14,EPB41,EPB41L1,LRRC17,RAB9B,DENND4A,HSPA12B,FCGRT,FDFT1,TESK2,FECH,SCARA3,FOXF2,SGIP1,SYT3,NBEA,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,WIF1,SYNPO,AGBL5,IL11RA,INPP1,ITPKB,JAK2,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,CD200,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PIRT,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,ZFHX4,MRAP2,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SCMH1,SMARCC2,RCOR3,PDZRN3,DOP1A,CDK19,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPC3,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,PMEPA1,NAV3,CERS6,SSPN,KLHDC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.24E-09 4.71E-05 8.31E-08 7.58E-07 29 60 "SORCS1,DPP10,PPFIA2,CADPS,CDH10,DCLK1,SYNPR,FAM171B,CRYM,JAKMIP2,GRIN3A,ST8SIA3,EYA1,FGF13,UBE2E3,SGIP1,GABRA1,INSM1,RSPO2,NAP1L2,NDP,CLDN11,CNTN3,GPR85,TRHDE,SCN3A,FAM19A1,ACSL6,HHIP" Coexpression Atlas PCBC_ratio_MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst_cfr-2X-p05 MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 9.78E-09 4.99E-05 8.78E-08 8.00E-07 328 1503 "EMILIN3,RNF157,CDC7,SORCS1,NLGN4X,ZNF608,HACE1,OSBPL1A,SORCS2,WDR35,OSBPL8,TXNDC16,SEMA6A,LTBP4,GPRASP2,CNIH2,APBA2,APLP1,TMEFF1,STK33,CCDC74A,ALDH4A1,ATP1A2,KIF1A,BCHE,BLM,BMP7,FUBP1,NIPA1,GPC2,WASF1,CARS,ARHGEF25,CBS,LGI1,LRWD1,NOG,UBE2L6,CACNA2D2,RCBTB2,CHN1,SLIT2,LHX2,RAB28,TMEM59L,HOMER3,CNTFR,IQCK,SLC25A27,COL9A1,COL9A2,COL9A3,SLC4A7,IFFO1,TCEAL2,RTTN,ZNF521,IGDCC3,CP,PREPL,ENTPD4,AKAP12,SNCAIP,LRIG1,FAM169A,GREB1,GPSM1,USP6NL,EDRF1,BOC,TOX,LONRF1,RIMS3,SPOCK2,AIF1L,MYEF2,SV2A,MTX3,ARNT2,DLG3,DLG4,DNM1,CD99L2,NR1D2,CDON,FARSB,E2F5,EEF1A2,CACNG7,EFNB3,ABI2,AASS,ASB3,PCOLCE2,C3orf18,EML1,EPB41,EFS,RTN3,EXTL2,CD320,REEP2,FAM198B,PSMA3-AS1,CEP78,CHST15,FKTN,PRMT5,ZNF589,GTF2IRD2,POLR1B,SPSB4,CAMSAP1,SUCO,MEX3B,CAP2,NOP56,SMC2,MSANTD4,ZNF512,GAA,FAM184B,DENND2A,GHDC,MTHFD2,TUBGCP4,GDF1,GPR162,GFRA1,GGT7,C1QL1,DBF4,TOX3,KDM2B,GP1BB,GPM6A,GPM6B,DIPK1C,STON1,GPR37,CNTRL,GRB10,CROCCP2,GRIK5,CIT,KIF3A,KAT7,RABL2A,PSIP1,RASSF8,HAS2,NXPH2,HMX1,IGFBPL1,CFAP126,CPT1C,HSF2,ZIC5,DOCK7,LRRCC1,LIX1,ITGAV,CDH20,KCNJ4,KLHL23,KIF5C,KPNA5,IPO5,TTYH2,STMN1,PAXBP1,MSANTD3-TMEFF1,LMO2,FGFBP3,SMAD9,CLEC18A,MAN2A2,MAP2,MAT2A,LDLRAD3,MEIS2,MEST,MN1,MSI1,MYCN,HNRNPM,NASP,RCOR2,NELL2,PAX6,PBX1,PCDHGC3,PRTG,GPR173,KCTD15,NLE1,FAM216A,PCDH18,PNMA3,LRP12,PSAT1,SDK2,FSD1,NKAIN4,CEP41,PKIA,PKN2,PROX1,LRRC49,PTCH1,PTPN13,PTPRZ1,NKAIN1,TMEM231,FEZF2,RBBP8,PRRT2,FIGN,UBR7,RGS10,KIF7,SEC61A2,NUDT11,CCDC82,ZNF532,PNMA8A,ROBO1,KIRREL1,TMEM206,MCMBP,LGR4,PLPPR3,SOX8,HSD11B1L,WLS,CCDC112,RMI1,SALL1,SARS,SLC30A10,CASC3,SFPQ,SCG5,SHMT2,CHD9,CLSTN1,PKNOX2,SLC6A9,YPEL4,CCDC88A,ANKRD36,LIMCH1,PALLD,SOX2,BDP1,SOX11,SPP1,ZNF423,KIF1B,TSPYL2,CLASP2,SST,SEPT3,STXBP1,SYT11,NUDT10,CAMSAP2,ADGRL3,AGTPBP1,TCF4,DMXL2,ZFP90,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA3,AKNA,SIRT1,ITGB3BP,LEFTY2,THBS4,ARL10,TIAM1,HEY1,CBX5,TMOD1,TMPO,PARD3,TP53BP1,RGMB,TRPC1,CA14,SSBP2,UCHL1,SLAIN1,USP1,CCDC136,CCDC14,VLDLR,LMF1,WRN,ZIC2,ZIC3,CRB2,TCEAL7,ZBTB16,TMEM237,DPYSL5,SMARCAD1,SYNC,MEIS3,DHX33,SLC38A1,TMEM178A,WNK2,PARP11,AMN1,FZD3,KAT6A,PHTF2,ACTR3B,VANGL2,PIANP,FRMD6,NETO2,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 9.85E-09 5.02E-05 8.83E-08 8.05E-07 96 334 "TTYH1,APLP1,CDH2,CDO1,CDR1,ADGRG1,CLU,COL4A5,ZNF521,CRMP1,CNTNAP2,KIAA0408,BOC,DPYSL2,RCAN1,SEZ6L2,EDNRB,EFNB3,ELAVL3,ENO2,ABCA8,TMEM132C,ZIC4,TUBB3,C1orf61,TMEM107,ERGIC3,GAP43,DNER,LOXL3,GPM6B,STMN2,GRM8,ATOH8,IGFBPL1,TUBB2B,OLFM3,KCNQ2,KIF5C,LAMP2,LIFR,LRP1B,TAGLN3,RSPO2,NFIA,NNAT,NTRK2,NUCB2,CNTN3,PAX6,PCDH9,PCMT1,PDE1A,PDE4D,PDPK1,PFKP,PKM,PLTP,SDK2,NECAB2,SLC36A4,POU3F2,NKAIN4,MAPK10,MASP1,PTN,TMEM255A,FAT4,ZMAT4,RFX3,RFX4,WLS,DRAXIN,SCN3A,HES6,GALNT10,PALLD,SOX11,KDM3A,CDK19,NPAS3,SYNE2,AGTPBP1,ZEB1,TCF12,TEX15,SLAIN1,ZIC1,ZIC2,ZIC3,ZNF711,TCEAL7,PRDM2,DNALI1,SLC38A1,NHSL1" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k3_500 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.03E-08 5.25E-05 9.20E-08 8.39E-07 56 161 "PNMA8B,PKP4,DOCK11,BACH1,RUNX1T1,SRSF11,CHM,SLIT2,COL4A5,RBM39,FGFR1OP2,TCAF1,AIF1L,ZEB2,ZC3H11A,EDNRA,EIF4G1,EMX2,EPB41L2,SMC2,APOPT1,GABRB1,TUBGCP4,SRCAP,PCDH11X,LPAR4,CHIC1,MEIS1,MEIS2,MMP16,MSI1,MYBPC1,NASP,CNOT4,KANSL1,MAPK8,TMEM255A,C1orf54,PBRM1,TMLHE,TRA2B,CHD9,SLC12A2,SCMH1,ZC3H13,TROVE2,AHCYL2,CBX5,SSBP2,FLRT2,PCDH20,ZNF711,ADAMTS9,NAV2,SNX27,GAN" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRgl_Subtype_iRgl1_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 1.08E-08 5.49E-05 9.62E-08 8.77E-07 31 67 "SYT13,VAT1L,LDB2,SEPT7,CHGB,NCOR1,ARHGAP32,EARS2,SEZ6L2,ELAVL3,B3GAT1,GAP43,GPM6A,STMN2,CELF3,SCRG1,CELF5,LSAMP,PAK3,TMOD2,PPP2R2B,PTN,SNAP25,SCN3B,PEG10,SEPT3,VGF,TRIM9,CELF4,STMN4,SCG2" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k3_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.17E-08 5.96E-05 1.04E-07 9.49E-07 79 259 "RNF157,PNMA8B,ARHGAP20,PKP4,ASPH,ATP2B1,DOCK11,BACH1,RUNX1T1,RGN,CDH2,ZNF445,SRSF11,SLIT2,PLAA,SLC4A7,TENM4,GAPVD1,KIAA0586,AIF1L,ZEB2,ZC3H11A,EDNRA,APH1A,EIF4G1,EPB41L2,SRRM1,SEMA6C,ANKFY1,SMC2,APOPT1,SRCAP,PPARGC1A,TNRC6A,LPAR4,DIDO1,KAT7,MAP4,CHIC1,MEIS1,MEIS2,MID1,MMP16,SAMD5,MSI1,NASP,OCRL,PCDH9,PCSK5,OLA1,PLEC,KANSL1,MAPK8,TMEM255A,C1orf54,PBRM1,RNASEL,TMLHE,MEG3,ATXN2,TRA2B,CHD9,TET1,ZC3H13,KIF1B,TROVE2,PRRC2C,SYNE2,TCF7L2,AHCYL2,CBX5,R3HDM1,SSBP2,FLRT2,NAV2,SNX27,FIP1L1,GAN,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.30E-08 6.61E-05 1.15E-07 1.05E-06 57 166 "METAP1D,ADCY8,AMPH,VAT1L,SEMA4G,ATP1A2,OSGIN2,CACNA2D1,CACNB4,CH25H,FAM19A5,ZFP28,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,DYNC1I1,DTNA,ELAVL4,TMEM35A,CDHR1,EYA1,FGF1,SCARA3,CAP2,SGIP1,DACH2,MEGF10,GABRB3,FUT10,CECR2,FAM107A,FRMD3,NEGR1,ITIH2,MYBPC1,FXYD6,NELL1,CNTN3,FAT3,NXPH1,PTHLH,PPP2R3C,ENOX1,ROBO2,RPS20,SALL1,ZFP2,SUPT20H,HSPA4L,ANKRD6,SLC1A3,SLC12A2,NEK4,TPM2,ZFAND5" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.45E-08 7.40E-05 1.29E-07 1.17E-06 76 247 "GALNT13,HECW2,PCDH10,FAM135A,LCORL,RUNX1T1,CBLN1,CDH2,DCLK1,CDO1,SLIT2,PLAA,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,HDAC9,TOX,PITPNC1,MAGI2,SPOCK3,EDNRA,EGFR,TENM1,EPHA5,SCML2,FOXF2,NBEA,MEGF10,GABRA4,DNER,GLRB,TOX3,RAB40B,LPAR4,GRIA2,IFI16,KCNA4,LSAMP,MYH3,DDR2,PAK3,PCDH8,NLGN3,PRRX1,ING3,MAPK8,ZIK1,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,SATB1,CSRNP3,LRRTM4,ZNF365,SON,TROVE2,TTBK2,KLHL7,UNC5D,ADGRL3,TBX15,PCDHB15,PSD3,PCDHB3,PUM2,SSBP2,UGT8,PCDH20,ZBTB14,PARP11,CBLN2,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_200 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.57E-08 7.98E-05 1.39E-07 1.27E-06 59 175 "GALNT13,RNF150,C1QTNF3,ALCAM,DPP10,DOCK11,IL33,CACNA2D1,LDB2,MYOM2,RASSF2,NTM,CALN1,EBF1,EDN3,SEMA3D,TMTC1,GABRA1,CHL1,IQGAP2,GGT5,GLRB,RAB40B,GRIA1,GRIA4,GRM3,GUCY1B1,WIF1,RASSF8,NEGR1,IFI16,KCND2,LSAMP,NOVA1,DDR2,PCDH8,PENK,RELN,FAT4,SALL1,CSRNP3,SCN3A,LRRTM4,SCN7A,FAM19A1,DOCK10,ST8SIA1,DZIP1,SLCO1A2,NEK4,ANO4,PCDHB9,ASXL3,TLR4,ZFP91,ERCC6L2,TTPA,PCDH20,SOCS4" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k3_200 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.61E-08 8.22E-05 1.43E-07 1.30E-06 14 18 "TUBB3,DPYSL4,GAP43,STMN2,INSM1,TUBB2B,KLC1,MAPT,NEFM,GNG2,SOX2,SYT11,PCBP4,VANGL2" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k3_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.67E-08 8.51E-05 1.48E-07 1.35E-06 31 68 "DCLK1,COL9A1,CRMP1,ST18,GSDME,ELAVL4,FABP7,TUBB3,NSG2,MEGF10,GAP43,DNER,STMN2,INSM1,TAGLN3,NAP1L2,NEFM,NEUROD1,PCDH8,FIGN,RGS4,ZFHX4,CSRNP3,DRAXIN,LINC00461,SLC1A3,SNAP25,SOX2,RBM26,ZIC1,ZIC3" Coexpression Atlas facebase_RNAseq_e10.5_MaxArch_2500 facebase_RNAseq_e10.5_MaxArch_2500 Gudmap RNAseq 1.84E-08 9.39E-05 1.63E-07 1.48E-06 346 1608 "ACHE,ACLY,ARID1A,SLC12A5,KIAA1211,RNF150,ADRB2,KIAA1324,SEMA6A,CEP126,FAM135A,DOC2A,LRCH2,APC,UPRT,BCAS1,LGR5,CDC14B,ARHGAP5,MARCH3,ASPH,PTCH2,ATM,NOL4,MYOM1,BCHE,BLM,ZNF599,PROM1,KSR1,BMP7,ST3GAL5,CACNA1G,GPC2,CA4,CA12,CACNA1A,CACNB2,HAP1,PTBP2,PRC1,ENTPD2,CDK11B,LRBA,SEPT7,CDC27,CCPG1,CRLF1,ADGRG1,ARHGAP22,SLIT2,NRXN3,C4orf33,NIPBL,CNR1,AKAP7,IQCK,PCYT1B,CABP1,COL9A1,SLC4A7,AHCTF1,IGDCC3,CP,CREB5,HAPLN1,CLIP3,CRYM,SNCAIP,FEZ1,IPCEF1,VCAN,FAM169A,DZIP3,PHF14,PNPLA8,GREB1,CFAP61,FGFR1OP2,KATNAL2,TOX,CENPL,EARS2,LIN54,PITPNC1,DNAJC6,KIAA0753,GSDME,DDX46,MTX3,FAM107B,DNM1,USP3,CASP8AP2,ACOT8,DTNA,DUSP9,ABCC9,EDNRA,OPTN,EGR3,LPAR6,EIF4G2,EIF5,ELAVL4,EMX2,PLEKHO1,EPB41,ANKRD13B,SLC43A2,SRRM1,CEP85L,ETV1,TLR7,CEND1,EYA1,MRVI1,WAC,PTK2B,CORO2B,ST3GAL6,ZSCAN30,FDFT1,FECH,CAMSAP1,SEC23B,ZMYND15,SGIP1,AFF2,NOP56,SYT3,SMC2,STAU2,TMEM151A,HIGD1B,KIAA1841,TUBA8,GDF9,GFRA2,FREM1,PCDH17,NTNG2,RND1,DBF4,GLI2,GLRB,TOX3,ZNF638,CBX1,EML4,CECR2,GRK4,CNTRL,RAPGEF4,GRIK2,PRDM5,CIT,KIF3A,MFSD2A,PSIP1,GUCY1A2,FAM107A,ADAMTS6,ATOH8,FRMD5,BACH2,HLF,HPCA,HSF2,HSP90AA1,SMAP1,ICA1,IGF1,DOCK7,LRRCC1,LIX1,ZNF385B,ITIH2,KCNC1,KCNJ5,KCNJ16,KIF2A,KIF5C,L1CAM,HECTD2,SMAD9,GPR155,MAP2,MBNL1,SHC3,MEST,MIA2,MID1,MITF,AFF1,SAMD5,N6AMT1,MXI1,MYCN,MYH7,LINC00672,TCEAL5,NASP,NEFM,NFE2L2,CNOT4,NPY,CLEC9A,NRGN,NTRK2,ODF2,CLDN11,P2RY1,PDE1C,PDE3B,PDE4D,ENPP2,TMOD2,FAM98B,CDK14,SERPINI1,RETREG1,GPSM2,PLCB2,PLP1,PCDH18,PRRX1,MAPK8,LRRC49,CNTLN,MTMR10,ELOVL2,SPDL1,ZIK1,NKAIN1,CCDC40,RAP1GAP,ARID4A,RBBP8,VEPH1,ZMAT4,REV3L,ERI2,FIGN,RFX3,RGS4,RNASEL,SETD5,MYH14,ACER3,HUNK,KCNIP3,CLIP1,SELL,SFPQ,SCG5,KIF21A,SH3GL2,CHD9,CNKSR2,ST3GAL3,ST8SIA1,DZIP1,ANKRD6,PREX2,PPP4R3A,DHX30,RUFY2,PKNOX2,CCDC88A,ZNF334,SLC14A1,TET1,SMARCC2,SMARCE1,IFT122,SNAP25,MBD5,PDZRN3,SOX2,TNIK,SOX5,ERC1,ARHGAP26,SPTB,RBM26,RAP1GAP2,TAB2,ATP10B,SAMSN1,SST,INKA2,ZSCAN29,SULF2,SEPT3,ACSBG1,SYNE2,VPS13A,TMEM150C,SYT5,ANKRD12,TAL1,SATB2,ZEB1,TCF12,NSD1,SIRT1,CHST8,C18orf54,AP4E1,AKTIP,GALNT17,TMPO,DAAM2,R3HDM1,PIK3R5,C9orf85,TPM4,PDSS1,STXBP4,TRPS1,CA14,TSC1,USP1,VSNL1,WNT7A,KLC2,XPO1,ZFP37,ZNF711,ZNF23,AGMO,SLC26A10,ZNF184,SMARCAD1,MAP3K12,EMSY,LRP8,EVI5,TUBA1A,WNK3,SSPN,KLHDC1,NETO2,ST8SIA2,SENP7" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K1 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.85E-08 9.43E-05 1.63E-07 1.49E-06 123 464 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,C1QC,LDLRAD4,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,DGKG,TIAM2,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,EPS8,PTK2B,DLL3,ABLIM2,FYB1,DKK3,GAA,ARPP21,GHDC,TMEM8B,GHR,LYVE1,NTNG2,GNG4,GRK4,GRIA1,GRIK4,TMEM25,GUCY1B1,HPSE2,ICA1,SCIN,IL11RA,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,CPNE9,MYH3,NEXMIF,TCEAL5,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,PEX5,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,PRIMA1,MYH14,STK32B,LRRK2,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,ARHGAP26,IQSEC2,C11orf87,NKAIN2,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,LRRC24,LAMP5,CADM2,LRP8,PCDH15,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.90E-08 9.67E-05 1.67E-07 1.52E-06 80 266 "ADCY2,SPARCL1,ALCAM,ARHGAP20,LTBP4,GPAM,LRRC4C,SLC4A4,SGCE,CACNA1G,MYRF,CACNA2D1,ARHGEF25,LDB2,LGI1,SLIT2,CNTFR,ZNF521,TENM4,ATRNL1,VCAN,BOC,ARMCX2,ZEB2,DNM1,EDNRA,SEMA3D,EGFR,LRRC17,FABP7,CAP2,FLNC,GFRA2,FREM1,CSDC2,GHR,GLI2,GUCY1A2,GUCY1A1,GUCY1B1,HPSE2,TCEAL6,LAMP2,MEIS1,NCAM1,NFIA,NFIX,NNAT,NME4,PCDH9,PDE3A,PDGFRA,PIK3R1,FXYD1,PCDH18,PRRX1,FAT3,PRKACB,LAMA1,PTN,TMEM255A,MEG3,ZNF354C,SATB1,SCN2A,DZIP1,PKNOX2,PALLD,PEG10,SULF2,PSD3,ASXL3,TPM1,TRPS1,AMOT,FLRT2,PLEKHH2,VSNL1,ZNF711,WNK1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.99E-08 1.02E-04 1.75E-07 1.59E-06 30 65 "SORCS1,VAT1L,CADPS,ASTN1,RNF182,DCLK1,CLGN,SYNPR,CNR1,CRYM,SCRN1,JAKMIP2,EPHA5,EYA1,SGIP1,NBEA,DACH2,PPARGC1A,RSPO2,NAP1L2,NDP,GPR85,TRHDE,FIGN,SCN3A,FAM19A1,ANKRD6,PCDHB10,PCDHB3,FMN2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k4 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.00E-08 1.02E-04 1.75E-07 1.60E-06 68 214 "HECW2,APAF1,USP37,RNF182,ADGRB3,SGCE,LDLRAD4,RUNX1T1,CDH2,CDH10,CDO1,NRXN3,ZNF521,NSL1,FAM171B,ANKRD44,TENM4,ARMCX4,TIAM2,BLOC1S6,RHOBTB1,NTM,GOLT1B,E2F6,ASB3,ELAVL4,ETV1,TMEM132C,MEX3B,FOXF2,SGIP1,TVP23A,MEGF10,GABRA4,GABRB1,PCDH17,STMN2,GUCY1A1,NEGR1,IFI16,KCNK2,MEIS2,RSPO2,NAP1L2,NDP,DDR2,PCDH8,GPR85,PFKFB3,PCDH18,LRP12,CEP41,RGS4,ZFHX4,C12orf49,TRA2B,DOCK10,ZNF365,LIMCH1,CMTR2,NPAS3,ZC4H2,PCDHB15,PCDHB7,ASXL3,HEY2,TMPO,RPRM" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_1000 kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.04E-08 1.04E-04 1.79E-07 1.63E-06 212 906 "ACADM,ACTN1,NDRG2,ADCY5,ADCY6,ADORA1,ESYT2,KIDINS220,MTUS1,KLHL13,ADGRF5,LRRC7,SPARCL1,ALCAM,APP,ASPA,ATP1A1,SLC4A4,ATP2A2,ATP2B1,ALDH7A1,MYOM1,ADAM23,PROM1,ARHGEF7,SGCE,CA4,CA8,CACNA2D1,CACNB2,CALB1,CLDN10,REPS2,DCLK1,LGI1,NDST3,SLC22A6,TPP1,ARHGEF6,CABP1,ABI3BP,C2CD2,AKAP12,VCAN,CTH,HDAC9,MYADM,RIPOR2,ARHGAP24,DGKB,NTM,FAM107B,CCDC3,KBTBD11,DMD,DMPK,ABCC9,EBF1,EDIL3,EDNRA,EDNRB,HEYL,SEMA3D,FRY,FAM13A,EGFR,CERCAM,ELN,EML1,CALCRL,RCAN2,LRRC17,RASGRP2,ERBB4,NCALD,ETV1,PIPOX,MRVI1,F3,ABCA8,SH3YL1,TUBB4A,EFEMP1,DLC1,ATP8A1,ST3GAL6,KIAA1109,FHL1,CAP2,PDLIM5,FUT9,PHYHIPL,IQGAP2,CPLX2,GATM,IGSF5,GCNT2,PPARGC1A,GK,TOX3,GNAO1,FERMT2,GP1BB,GPM6A,RAPGEF4,ADAMTS8,NR3C1,GSN,GUCY1A2,ADAMTS6,GUCY1A1,GUCY1B1,HPSE2,HSPA1L,PLD5,SCIN,IL6ST,DIPK1A,SLC6A17,LRRTM3,ITGAV,KCNJ16,LMO1,HECTD2,GPR155,MARK1,MEF2C,CCDC80,ADAM22,CTNNA3,MYH3,MYO6,NCF2,NFIX,NTRK3,DDR2,PCSK2,PDE1A,PDE3A,PDE4D,ENPP2,PENK,PFKP,PGAM2,SERPINE2,SERPINI1,PLCL1,FXYD1,PURG,SEPT4,FAT3,MINDY2,PKIA,MAPK10,RELN,CNNM2,SYTL2,LAMA1,SNRK,PTH1R,PTPRB,PYGM,TMEM255A,ZDHHC14,FIGN,SUGCT,RERGL,LRRK2,SALL1,ATXN1,SH3BGR,PPM1E,NTNG1,SLC4A3,FAM81A,SMTN,SLC6A9,SLC8A1,SLC12A2,SLC15A2,EFHD1,CPEB4,LIMCH1,LMBRD1,SPP1,ELOVL4,ADHFE1,NUDT10,ADAMTS17,PLCB1,CUX2,SYNE1,HIF3A,TEK,THBS4,HEY2,TNS1,TPM1,TPM2,TRPC1,TRPC3,PPIL6,UCHL1,UGT8,VLDLR,KCNT2,PMEPA1,ADAMTS9,KCNAB1,RGS7BP,PHTF2,MSRB3" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.05E-08 1.04E-04 1.79E-07 1.63E-06 58 172 "RNF157,PNMA8B,INTS2,TAOK1,LCORL,PKP4,BACH1,RUNX1T1,CDH2,ZNF445,CHM,SLIT2,RBM39,FGFR1OP2,TCAF1,AIF1L,ZEB2,ZC3H11A,EIF4G1,SRRM1,SMC2,APOPT1,TUBGCP4,PCDH11X,LPAR4,CHIC1,MEIS2,MMP16,MSI1,NASP,PRRX1,MAPK8,CEP97,C1orf54,PBRM1,TMLHE,PCMTD2,MEG3,TRA2B,SLC12A2,SCMH1,CPEB4,ZC3H13,KIF1B,TROVE2,CLSTN2,SYNE2,AHCYL2,CBX5,R3HDM1,SSBP2,FLRT2,ZNF711,TRIM9,ADAMTS9,SNX27,GAN,SENP7" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_500 DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.35E-08 1.20E-04 2.05E-07 1.87E-06 111 409 "SLITRK1,ADD1,PNMA8B,PWWP2A,INTS2,NR0B1,TAOK1,LCORL,PKP4,INSYN2B,RNF182,DOCK11,BACH1,CALB1,RUNX1T1,CDH10,SRSF11,CHM,SLIT2,NMT2,QKI,CNR1,COL4A5,RBM39,TENM4,FAM169A,PUM1,DOCK4,FGFR1OP2,TCAF1,AIF1L,DCT,ZEB2,ZC3H11A,GSDME,DRP2,EDNRA,PLXNC1,EIF4G1,ELAVL2,EMX2,EPB41L2,SCML2,MEX3B,SMC2,APOPT1,GABRA4,GABRB1,TUBGCP4,SRCAP,PCDH11X,LPAR4,GPR37,MAEL,INSM1,KCND2,CHIC1,MEIS1,MEIS2,KITLG,MMP16,MSI1,MYBPC1,NASP,NEFM,CNOT4,SERPINI1,KANSL1,MAPK8,TMEM255A,C1orf54,PBRM1,ZFHX4,TMLHE,ROBO2,PCMTD2,MEG3,CSRNP3,FNIP1,SFPQ,TRA2B,ARX,CHD9,SYBU,SLC12A2,SCMH1,SPHKAP,CPEB4,ZKSCAN3,SOX2,ZC3H13,RBM26,TROVE2,LARP4,SYNE2,KLHL4,AHCYL2,CBX5,ACTR6,ASXL3,NR2C2,SSBP2,FLRT2,PCDH20,ZIC3,ZNF711,EMX2OS,ADAMTS9,NAV2,SNX27,GAN" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_500 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_500 FaceBase_ST1 2.37E-08 1.21E-04 2.06E-07 1.88E-06 108 395 "DPF1,CPNE2,TTYH1,C3orf14,NR0B1,TAOK1,TMEM263,ZBTB10,RNF182,PTBP2,CANX,CDH2,ADGRG1,JAM2,LHX2,RAB33A,NECTIN3,FEZ1,KATNAL2,ZFYVE16,SCRN1,GSDME,SRGAP3,OLIG1,ELAVL4,C8orf37,EMX2,OLIG2,CDKL3,KATNAL1,NRN1,FABP7,ZIC4,IQCG,EFCAB2,CSPG5,STAU2,TPPP3,CAB39,C15orf41,GATM,SESN1,GLDC,RAB30,TOX3,GPM6A,TDRKH,CACFD1,MFSD2A,IGFBPL1,USP51,LIX1,TUBB2B,PACRG,LYPLAL1,CHIC1,SESN3,SCG3,TAGLN3,RSPO2,NAP1L2,NELL2,NEUROD1,NTRK2,PAK3,PAX6,ETFRF1,SLC25A23,ZNF426,MINDY2,PPP2R5E,NKAIN4,PKIA,GDPD1,PTPRZ1,FEZF2,SLC25A36,NUDT11,PBRM1,ARMH4,CCDC112,SCN2A,LINC00461,SCP2,HSPA4L,SCG5,KIF21A,SLC4A3,EFHD1,SOX2,NPAS3,SYT11,NUDT10,ADAMTS17,DMXL2,RALYL,CCDC173,HEY1,NR2E1,NPL,PRMT8,TRPS1,FAM181B,XRCC4,ZIC1,GOPC,AMN1,NETO2" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.43E-08 1.24E-04 2.11E-07 1.92E-06 25 49 "ATP2B2,KIF1A,SRSF11,NRXN2,IGDCC3,ST18,SCRN1,ELAVL3,ADGRV1,CLVS1,FUT9,GAD1,SRRM4,PPARGC1A,PCLO,GRIK2,CELF3,ATCAY,IGSF1,HES5,INSM1,MYT1,GDAP1L1,MAPK10,STMN4" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000 dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.43E-08 1.24E-04 2.11E-07 1.92E-06 189 791 "C3orf14,CSMD3,FMNL2,SLITRK1,MTA3,HECW2,KLHL13,NR0B1,ARHGAP20,KCNT1,MRTFA,CDC42BPA,SEMA7A,EPB41L5,APOC1,CACHD1,LGR5,CDC14B,PPP4R4,IGDCC4,ARHGDIG,NUMB,INSYN2B,ATP2B3,RNF182,RGS11,DST,ST3GAL5,WASF1,BTRC,CACNA1D,CACNB2,CALB1,RGN,SLC16A4,DCLK1,MAGI1,ADGRG1,CHRM4,NMT2,PLXNA4,DOCK4,GPRASP1,DAPK1,DBI,DCT,HP1BP3,USP3,CDON,CPEB2,DRP2,DTNB,RASGRP1,KLHL5,SIDT2,ABI2,PLXNC1,SORBS3,CERCAM,TMEM35A,EMX2,EPB41L1,MTSS1L,EPS8,CEP85L,NRN1,F8,IP6K2,AFF2,CAMKK2,ZMAT1,GABRA4,GABRB1,TRAF3IP2,GALC,GART,RAB30,PCDH11X,GPR37,GRK4,GRIK5,GUCY1A2,PACSIN2,FRMD3,SHISA6,IGF1,IL6ST,LRRTM3,KCND2,KCNH1,KLHL23,SYTL4,NCOA7,MAOB,MAP2,MATN2,MEIS1,KITLG,SCAMP5,AFF1,MOV10,SESN3,CCDC80,CTNNA3,MTR,MYO9A,NEXMIF,NELL2,NFIA,NFE2L2,SLC11A2,NUCB2,ETFRF1,PDE1A,SERPINI1,PIK3C2A,PIK3R1,PCDH18,PPARA,LRRN3,PPP3CC,GDPD1,PTPRG,PEX2,SH3TC2,FAT4,REV3L,ZFHX4,TMEM206,RPS6KA2,LGR4,HUNK,SEMA6D,ATXN2,PRCD,TNFRSF19,STUM,MRAS,RASA3,FRMPD1,ST8SIA1,WDR37,ABLIM3,SLC4A3,SLC1A6,SCMH1,ATF7IP,SNCA,FAIM2,SOX5,KDM3A,UHRF1BP1L,PEG10,TSPYL2,LHPP,SMOC1,LRRC4,ST5,FGD4,SLC37A2,ADGRL3,RPGRIP1L,DOCK9,OBSL1,CCDC173,TEX15,DNAH7,ZFPM2,HEY1,ACTR6,KAT6B,TNNT1,TRPS1,FNDC5,TST,UBE2H,PLEKHH2,VAV2,PCDH20,ZNF23,ELFN1,LYPD6,REEP1,ADAMTS9,SIGLEC10,NAV2,WNK3,FRMD6,DPF3" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K1 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.69E-08 1.37E-04 2.33E-07 2.12E-06 132 510 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,KIAA1324,OSBPL6,SMIM17,SRPX,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,C1QC,LDLRAD4,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,DGKG,TIAM2,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,EPB41L1,RAB9B,EPS8,ARMCX1,PTK2B,FCGRT,SGIP1,TPK1,DLL3,ABLIM2,FYB1,DKK3,GAA,ARPP21,GHDC,TMEM8B,GHR,LYVE1,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,ICA1,SCIN,IL11RA,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,CPNE9,MYH3,NEXMIF,TCEAL5,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,SDK2,PILRA,NXPH1,PRKAR1B,MASP1,PEX5,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,MORC4,PRIMA1,MYH14,STK32B,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,TNIK,ARHGAP26,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,ATP13A2,TMOD1,LRRC24,LAMP5,PMEPA1,CADM2,LRP8,PCDH15,CERS6,DPF3,PRRT4" Coexpression Atlas JC_iEC_2500_K1 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#1 PCBC 2.78E-08 1.42E-04 2.40E-07 2.19E-06 166 677 "ASIC2,ADRA1D,SLC44A5,HECW2,KLHL13,CASKIN1,PCDH19,KIAA1324,SORCS2,BCAR3,MARCH4,PCDH10,BBOX1,AMH,CDC42BPA,SLC7A14,INSYN2B,NRP2,ST3GAL5,MYRF,CALB1,THSD7A,CH25H,CDH10,LGI1,NOG,SYNPR,NMT2,NGEF,TMEM155,CPS1,CALY,DCC,C8orf34,CNIH3,MFAP3L,SACS,GRIN3A,DPP6,MAMLD1,TMTC1,TENM1,CALCRL,EN2,CD320,HSPA12B,FAM198B,TUBB3,FOXG1,DLL3,PNMA2,HHIPL1,NRG3,ILDR2,GAP43,DNER,GBX2,LNX1,MCHR1,STMN2,GRM7,BVES,SLC2A6,TOX2,ARHGAP36,MIER3,KCNF1,GIT1,SAMD5,MSR1,NDP,NELL1,NPY,NRCAM,OPCML,OXTR,SNTG1,PCDH9,PCSK1,PCSK5,PDE4D,TRHDE,FA2H,PKN2,MAPK3,MAPK7,PRPH,RELN,SNRK,PTCH1,PTPRB,PTPRE,PTPRG,PTX3,RIPOR1,RASGRF1,RGS4,RLBP1,ROBO2,RPE65,TMEM100,RPS6KA2,STK32B,SOX8,SCN3A,SEC14L1,SGK1,ZFP30,ST6GAL1,NLGN1,BTBD3,LRRC55,SLC12A2,SLIT1,CXXC4,OGDHL,SNAP25,SOX1,SOX5,SOX11,SPP1,SPTAN1,ITPRID2,THSD1,SST,SSTR1,SULF2,PLCB1,ARC,SYT5,TAC1,POPDC3,ADGRL3,KLHL4,ANO4,TBX15,TCF4,SATB2,TCF7,ZEB1,TCF12,PCDHGB6,PCDHGB2,SLC35G2,TEK,ZFPM2,ARL10,TIE1,ASXL3,TLR4,NR2E1,TPM4,TRH,TRIO,TRO,TRPS1,VLDLR,TRIM9,LYPD6,CELF4,EML6,LAMP5,TMEM178A,SCG2,NETO2,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.86E-08 1.46E-04 2.47E-07 2.25E-06 109 401 "SLITRK1,AXIN2,SORCS1,PCDH19,SEMA6A,DOC2A,FGD2,EPB41L5,AQP4,PDE8B,ZNF599,BMP7,BMPR1B,CA12,CACNA1B,CALB1,MAP7,CRLF1,B4GALT6,TMEM59L,HAPLN1,SLC32A1,IPCEF1,PHACTR3,CNTNAP2,KIAA0040,CTH,GREB1,CTNND2,KATNAL2,RAB39B,DUSP9,TENM1,EMX2,ENO2,SPSB4,FGF12,SEMA4D,RASL10A,PRELID3A,GALC,GAP43,GFRA1,KIRREL3,MAP7D2,CNDP1,B4GALNT4,GRIK1,GRIK2,FAM19A2,MFSD2A,PADI2,FRMD5,IGFBP1,SLC35G1,KCNJ16,KCNK1,KIF5C,L1CAM,C2orf80,AQP11,KITLG,VWA2,NRCAM,PRTG,PFKFB3,SEMA5B,SLC25A23,HMGCLL1,PLXNB1,LAMA1,EML5,NKAIN1,CCDC40,FAM184A,RASGRF2,GAL3ST4,RET,NUDT11,PRR5L,EMID1,SOX8,SCN2B,SCN3A,SCN4B,SCN8A,SHMT2,FHOD3,RAP1GAP2,LRRC4,SYT11,NUDT10,TMEM150C,UNC5D,WWC1,WSCD1,TCF7,PRMT8,DCBLD1,CA14,RPRM,SLAIN1,VSNL1,SF1,EMX2OS,FSTL5,LRP8,TMEM178A,FZD3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.00E-08 1.53E-04 2.58E-07 2.35E-06 101 364 "KDM5D,GRAMD1B,ALCAM,ARHGAP20,LTBP4,AMH,CDC14B,CADPS,DDX3Y,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SCARB1,SLIT2,CLU,ZNF521,TENM4,MICAL2,VCAN,RIPOR2,ARMCX2,ZEB2,EDNRA,EGFR,MRO,PLXNC1,LRRC17,EPS8,NRN1,FAM198B,FABP7,PTK2B,DLC1,FGF13,FLNC,AFF2,GABRA4,TRAF3IP2,IQGAP2,GATM,GFRA2,FREM1,GHR,PPARGC1A,GLI2,PCDH11X,ADGRA3,GPM6B,GRIA4,GUCY1A1,GUCY1B1,KLHL23,MATN2,MEF2C,MEIS1,NCAM1,NFIA,PAK3,PCDH9,PDE1A,PDGFRA,SERPINE2,PCDH18,PLTP,FAT3,LRRN3,RASGEF1B,MASP1,LAMA1,PTCH1,PTN,TMEM255A,REV3L,ROBO1,ROBO2,TMEM206,ARMH4,GLDN,ACER3,LGR4,SOX6,DOCK10,PALLD,SMOC1,ST5,SULF2,ADGRL3,OBSL1,ZFPM2,TGFBR3,HHIP,THRA,TPM1,TRPS1,TMEFF2,VSNL1,STOX2,ADAMTS9,WNK3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.05E-08 1.56E-04 2.63E-07 2.39E-06 122 463 "ASPHD1,CSMD3,RNF157,ALAD,VAT1L,ARHGDIG,CADPS,KIF1A,NRP2,C1QC,CACNA1G,INA,DCLK1,CHGB,RAB33A,CLTB,PICK1,CNTFR,FAM171B,CRMP1,CLIP3,FEZ1,VCAN,PLXNA4,NRSN1,SCRN1,BRINP1,GRIN3A,DNM1,EDNRA,CACNG7,ELAVL2,ELAVL4,LRRC17,EYA1,FABP7,TUBB3,TUBB4A,EFEMP1,FGF13,FLNC,NSG1,TPPP3,TVP23A,GAP43,SYT17,IGSF5,GFRA1,GFRA2,FREM1,GLI2,PCSK1N,KCNMB4,GNAO1,GNG3,B4GALNT4,STMN2,GSTM5,CELF3,ACOT7,HPSE2,LIX1,TUBB2B,L1CAM,SYTL4,MATN2,CCDC80,SCG3,TAGLN3,NCAM1,NEFM,NELL2,NFIX,NNAT,NME4,NPY,PCBP3,NTRK2,NTRK3,CLDN11,PDGFRA,SLC10A4,PENK,GDAP1L1,SERPINE2,FXYD1,PMP22,PRRX1,FAT3,POLR2F,NKAIN4,MAPK10,PRPH,MASP1,EML5,TMEM255A,TSPY26P,RET,HUNK,RTN1,FAM19A1,SCG5,SNAP25,SCN3B,SST,EPB41L3,SULF2,SEPT3,SYT11,ADAMTS17,SYP,SYT1,ASTN2,CUX2,TNNT1,TMEFF2,CADM1,UCHL1,MTCH1,VLDLR,STMN4,MVB12B" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.18E-08 1.62E-04 2.73E-07 2.49E-06 37 91 "SORCS1,PCDH10,CADPS,CDH10,DCLK1,CHGB,SYNPR,ELAVL4,EPHA5,EYA1,TMEM132C,FOXF2,SGIP1,DACH2,DNER,STMN2,WIF1,IFI16,MAP4,RSPO2,MYH3,NEFM,CLDN11,GPR85,TRHDE,MAPK10,PRPH,RGS4,ZFHX4,CSRNP3,SCN3A,FAM19A1,SNAP25,SCN3B,SOX2,C11orf87,TAC1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.25E-08 1.66E-04 2.79E-07 2.54E-06 90 314 "DPF1,NDRG2,PTCHD1,SPARCL1,LTBP4,GAS7,CASK,RGS20,RUNX1T1,CD81,CDO1,CHRM4,B4GALT6,SLIT2,MAGED1,CP,AKAP12,VCAN,NCAN,DOCK4,HDAC9,ZEB2,BLOC1S6,DMD,SHANK1,DPYSL2,ABCC5,EDNRA,PCOLCE2,LRRC17,EPHA5,ETV1,FGF13,FHL1,JKAMP,DKK3,CPLX2,AHDC1,FREM1,HTATSF1,FERMT2,GPM6B,RAPGEF4,GRB10,DIDO1,GSN,GUCY1A1,GYG1,HNF4G,IGF1,ITGAM,KCNA2,CHIC1,MN1,NDP,NFIA,PAX6,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,POU3F2,NKAIN4,PTCH1,CEP97,ZYG11B,ROBO2,S100B,TNFRSF19,LIMCH1,LMBRD1,PALLD,TRERF1,CAND2,MYCBP2,C11orf87,CLASP2,SAMSN1,SYT11,FGD4,PDLIM2,TCF7L2,TGFBR3,HHIP,NACC2,FNDC5,ZIC1,JPH3" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_1000 kidney_P1_CapMes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.32E-08 1.70E-04 2.84E-07 2.59E-06 157 634 "ABR,ASIC2,NDRG2,RNF157,ZNF608,MTUS1,TXNDC16,CC2D2A,ALCAM,CEP126,AMPH,ANK3,SEMA4G,CASK,ADAM23,BCHE,BCL7A,BMP7,DST,IL33,CA12,CACNA2D1,CACNB4,LONRF2,CDH2,CNTFR,BTF3L4,ABI3BP,AKAP12,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,ECE2,PHF19,SPOCK2,GSDME,SNAP91,MTX3,ARRDC4,DTNA,EDNRA,ELAVL4,C8orf37,CALCRL,KCNMB2,ERBB2,ETV1,RRAGB,EXTL2,EYA1,ST3GAL6,FCGRT,SLC9B2,FGF1,FGFR1,MAD2L2,SCARA3,NOP56,TMEM107,STAU2,WASF3,IGSF5,FAXC,GFRA1,FREM1,GLDC,GLRB,TDRKH,B4GALNT4,CECR2,CNTRL,PARD3B,GRIK4,CACFD1,FAM107A,ADAMTS6,HAS2,NEGR1,HSPA1L,KHK,MAT2A,MEIS2,MEST,MMP16,MSI1,ADAM22,NCAM1,NELL1,NFIX,NME4,NPR2,CNTN3,PRTG,ENPP2,PENK,SMOX,ANKRD16,FAT3,PPP1R1A,CEP41,PKIA,PRODH,MASP1,MDGA2,PTN,PYGM,RBBP6,TSPY26P,NUDT11,RAVER2,ROBO2,TMEM100,HUNK,ZNF354C,SALL1,SCN2A,FAM19A1,ASRGL1,SCG5,PPM1E,DZIP1,SLC1A3,SLC4A3,YPEL4,SEPHS1,SLC12A2,SLC20A2,GKAP1,LIMCH1,CMTR2,NPAS3,SULF2,NUDT10,ADAMTS17,CAMTA1,CUX2,TRIM2,PCDHB10,PCDHB9,PCDHB7,PCDHB3,FRYL,TMOD1,TPM2,PPIL6,CADM1,NDRG4,MKRN3,LAMP5,SLC38A1,SIGLEC10,FZD3,SSPN,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.33E-08 1.70E-04 2.85E-07 2.60E-06 106 388 "NDRG2,ADCY5,SPARCL1,ANK1,PI16,ATP1A2,ATP2A2,MYOM1,NRP2,CACNA2D1,NGB,CAMK2D,CLDN10,NEURL1,CFL2,RAB3C,AKAP6,AKAP5,ABI3BP,RABGAP1L,DMPK,CPEB2,DTNA,ABCC9,SH3GLB1,ELN,EML1,PLEKHO1,NCALD,MRVI1,PRKAG2,FHL1,CAP2,FLNC,SORBS1,DKK3,DNER,IGSF5,GCNT2,GFRA2,RAB40B,FERMT2,PRUNE2,TPPP,BVES,HNMT,IFI16,SHISAL1,IL6ST,KCNB1,KCND3,KCNF1,MBP,IL17D,MMP17,NRBP2,MYH3,MYH7,ALDH1L2,NPTX2,HCN1,PDE4D,PFKP,TMEM38A,FXYD1,SCHIP1,PRKCB,PSD,PTHLH,TTLL7,RYR3,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,ABLIM3,SMTN,LIMS2,RIMS1,SCN3B,TNIK,FNBP1,DBNDD2,SRPK2,NACAD,ARHGEF9,SYN2,POPDC3,TEX15,ENHO,NACC2,TNNT1,TNS1,TPM1,TPM2,RGMB,SYNPO2,PPIL6,MICAL1,RBFOX3,PLSCR4,RGS7BP,FAM13C,ACTR3B,MSRB3" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_200 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.39E-08 1.73E-04 2.89E-07 2.64E-06 57 170 "ADORA1,NR0B1,AMH,SEMA7A,GAS7,SHTN1,LGR5,ARHGDIG,CADPS,ADGRG1,JAM2,CLU,TOX,SCRN1,JAKMIP2,ELMO1,PLPPR4,DTNA,MRO,PLXNC1,CERCAM,EPS8,ERBB4,PTK2B,TUBB3,FGF13,SEMA6C,AFF2,GATM,GPM6B,GPR37,SHISA6,KCNH1,KLHL23,SYTL4,MOV10,MYO7A,PAK3,PGAM2,SERPINE2,RASGEF1B,DUSP15,TMEM206,MRAS,KIF21A,SH3GL2,EFHD1,TNIK,SPP1,SMOC1,TACC1,THRA,DAAM2,BEX4,SGK3,ADAMTS9,WNK3" Coexpression Atlas geo_heart_2500_K5 geo_heart_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 3.46E-08 1.76E-04 2.95E-07 2.68E-06 148 590 "HHATL,LCNL1,DPY19L2P4,HFM1,CARNS1,TRMT9B,PI16,MYH7B,PPFIA4,DDO,CPNE5,KIAA1614,SPTBN4,PDE8B,TMEM108,SLC4A4,SLC2A11,RGS11,HCN2,DIRAS1,CAMK2B,VXN,USP2,RGN,P2RX6,LONRF2,CFL2,CHGB,JAM2,FAM189A2,COL9A1,TOGARAM2,CRYM,RABGAP1L,DTNA,EGR3,ELN,C3orf18,KCNMB2,RAB9B,DUSP27,RASL12,F5,FGF1,FGF12,FHL1,SEMA6C,NSG2,TPPP3,DKK3,HRASLS5,CPLX1,MYOZ2,IGSF5,TUBA8,CYP46A1,AHDC1,GFAP,GFRA2,GHR,PPARGC1A,NTNG2,PCDH11X,GNAO1,GPM6A,DIPK1C,GPR17,TMEM121B,RAPGEF4,TPPP,PLPP7,SPACA9,GRIN2C,BVES,MAEL,UBE2QL1,NXPH3,FRMD3,SCRG1,SYNPO,C9orf129,HP,FAM95B1,LRRC25,KIAA1755,IL11RA,ZNF385B,CDH20,KCND3,KCNJ3,KCNJ4,KCNK1,KCNK3,ADAM11,MOG,COL28A1,MT3,MYBPC1,MYH6,NPPA,NTRK2,CDK18,PGAM2,ST8SIA5,PACSIN1,VSTM2L,PROX1,SMIM10L2B,RAB3A,CRTAC1,SGSM1,SYNDIG1,RXRG,S100B,HOGA1,SCN2B,CPEB3,SLC1A7,SMTN,PKNOX2,SLN,SMARCD3,IGSF9B,NMNAT2,CAND2,IDI2-AS1,NFASC,CLSTN2,KANK1,ABCC8,SYN1,SYT4,POPDC3,ACSL6,VWC2,SYNE1,TNNT1,TPM2,FNDC5,ANO5,VLDLR,REEP1,SHD,SEMA3B,GAL3ST3,WNK2,EPM2A,ADAMTSL3" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000_k5 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.47E-08 1.77E-04 2.95E-07 2.69E-06 69 221 "TKTL1,INTS2,LCORL,LGR5,PDE8B,ASPA,CAPRIN2,DDX3Y,INSYN2B,RNF182,SYNJ1,ARHGEF7,CALB1,LONRF2,KMT2C,CNR1,GREB1,DOCK4,MAGI2,SACS,RABGAP1L,DYNC1I1,DOCK2,DRP2,DTNB,RASGRP1,EMX2,ATP8A1,KIAA1109,ATP6V1H,ZMAT1,GABRA4,GRK4,KCND2,KITLG,MYO5A,MYO9A,NEXMIF,GLIPR1L2,PDPK1,SERPINI1,TMIE,JAKMIP1,PLP1,SEC61A2,RYR1,SEMA6D,LRRTM4,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,SNCA,TNIK,SOX5,ARHGAP26,SLC37A2,CCDC173,DNAH7,ACTR6,FNDC5,ZNF711,ZNF23,EMX2OS,REEP1,TMEM178A,PHTF2,KLHDC1" Coexpression Atlas GSM605843_500 "Plasmacytoid, DC.pDC.8-.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 3.59E-08 1.83E-04 3.05E-07 2.78E-06 111 412 "CPNE2,ABHD6,FMNL2,SNX30,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ARHGAP5,ASPH,ZBTB10,ATP1A3,CACNA1D,CACNA1E,DDR1,CD38,STOML1,FADS2,LY86,MAGED1,ZNF521,ATRNL1,CST3,CTNND2,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,SIRPA,ZEB2,SRGAP3,RABGAP1L,GNE,TOM1,DUSP9,SNX29,EGFR,PLXNC1,CEP85L,TLR7,EYA1,CHST15,FGR,TMEM107,HVCN1,AK8,FYN,NEK6,GPR162,GPM6B,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,TUBB2B,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,MATN2,ADAM11,LDLRAD3,MEF2C,MX1,MYO5A,P2RY13,CLEC9A,NUCB2,PLTP,CDIP1,PACSIN1,PTAFR,ROGDI,ZDHHC14,FOXRED2,SCN3A,IL17RB,SELL,ITSN1,PPM1E,ST8SIA1,BTBD3,CCDC88A,ZCCHC24,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,TCF7L2,CYB561A3,ATP13A2,SLC44A1,TNS1,TPD52,VAV2,P2RY12,LAT2,LRP8,EVI5,SIGLEC10,TMEM163,PLD4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkD_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.65E-08 1.86E-04 3.09E-07 2.81E-06 26 53 "ASCL1,INA,SEPT7,NRXN2,ELAVL4,EN2,FABP7,TAOK3,C1orf61,NSG2,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,STMN1,NCAM1,VEPH1,RTN1,SCN2A,SCN3A,MYT1L,TCF12,TSPAN11,CELF4" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.88E-08 1.98E-04 3.28E-07 2.99E-06 113 422 "EMILIN3,RNF157,ALCAM,FAM135A,APAF1,PHYHD1,MYOM1,BCHE,NRP2,NIPA1,LDLRAD4,CACNA2D1,CAMK2D,RUNX1T1,CDH2,SLIT2,AKAP5,ABI3BP,NCOR1,VCAN,APPL1,ZEB2,CEP170,EDIL3,EPHB1,ETV1,MRVI1,TMEM132C,DLC1,UBE2E3,FOXF2,PDLIM5,PNMA2,ZMAT1,DKK3,MEGF10,GABRA4,CHL1,GABRB1,GABRB3,DNER,PCDH17,GHR,LYVE1,GLRB,PCDH11X,RAB40B,GPM6B,RAPGEF4,MAP4K5,RASSF8,IFI16,KCNK2,KIT,MAOB,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,RSPO2,NAP1L2,NAP1L3,ALDH1L2,NPTX2,HCN1,PCDH8,PDE4B,GPR85,ANLN,PCDH18,PRKCB,GRAMD1C,FAT4,RGS4,ZFHX4,SETD5,ARMH4,SCN7A,DZIP1,WDR37,SLC14A1,SPHKAP,SOX5,ZHX3,PEG10,NPAS3,C11orf87,THSD1,ELOVL4,PLCB1,COBL,MTCL1,ADGRL3,TEK,ZFPM2,HHIP,TLR4,ERCC6L2,RBFOX2,RGMB,SYNPO2,TRPS1,UBE3A,WRN,MKRN3,CELF4,GOPC,FAM13C,ACTR3B,MSRB3,NETO1,SOCS4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.90E-08 1.99E-04 3.29E-07 3.00E-06 192 811 "EMILIN3,RNF157,ADD3,SLC12A5,USP31,AP2A2,TBC1D14,TAOK1,ALCAM,AMPD3,OGT,APAF1,APC,PHYHD1,TMEM263,ATP2B1,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,CANX,RUNX1T1,NEURL1,CDH2,CDO1,SRSF11,SLIT2,AKAP5,PREPL,RBM39,NCOR1,VCAN,DZIP3,APPL1,PYGO1,HDAC9,TM9SF4,ZEB2,MYEF2,MFAP3L,CEP170,AK5,KBTBD11,PDCD6IP,DYRK1A,EDIL3,TSPAN5,EDNRB,HIPK3,SEMA3D,EIF4G1,CALCRL,DCTN4,ENO2,EPHB1,ETV1,MRVI1,NRN1,SCML2,DLC1,KIAA1109,SUCO,CAP2,FOXF2,FLT1,SMC2,PDLIM5,CAMKK2,CELF1,PNMA2,DKK3,MEGF10,GABRA3,GABRA4,CHL1,GABRB1,AHCYL1,IQGAP2,PCDH17,GHR,LYVE1,PCDH11X,RAB40B,FERMT2,GPM6B,EML4,GPR37,RAPGEF4,GRB10,NR3C1,RASSF8,HAS2,KLF12,ZDHHC15,IFI16,RBPJ,IL6ST,JAK1,KCNK2,KIT,LIFR,LIMS1,IL17D,CHIC1,MEF2C,MEIS2,KITLG,MKLN1,MMP16,SAMD5,CCDC80,NAP1L2,NCAM1,NFIA,NFIX,NPTX2,HCN1,PCDH8,PDE1A,PDE3A,PDE4B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,PRKCB,GRAMD1C,PTPRD,FAT4,RGS4,KLHL11,ZFHX4,SETD5,RPE,ARMH4,MEG3,CLIP1,ATXN1,ASRGL1,TRA2B,SH3BGR,PPP1R9A,PREX2,SLC14A1,SLC15A2,SPHKAP,CPEB4,SON,SOX5,ZHX3,PEG10,NPAS3,C11orf87,SRPK2,CLASP2,THSD1,EPB41L3,LARP4,MAPK8IP3,PLCB1,COBL,MTCL1,PJA1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,HIF3A,ZFPM2,HHIP,TLR4,ERCC6L2,TNNT1,RBFOX2,TPM2,RGMB,SYNPO2,TRPS1,UBE3A,WRN,CLDND1,STOX2,SNX27,FAM13C,NUP214,ACTR3B,MSRB3,NETO1,SOCS4,SPATA13" Coexpression Atlas PCBC_DE_1000 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000 PCBC 4.15E-08 2.12E-04 3.50E-07 3.19E-06 227 991 "KCNH8,CSMD2,TMEM132B,ADCY2,GALNT13,SORCS1,ERMN,PTCHD1,NLGN4X,NR0B1,ZNF578,SEMA6A,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,CNIH2,APOC1,CACHD1,SHTN1,LGR5,SLC7A14,PPP4R4,ARSE,RASL11B,KIF1A,FGF17,BTK,CACNA1I,CACNA1G,BAIAP3,CALB1,SYT6,BRSK2,MAP7,CLDN10,CCKBR,USP2,CDH10,DCLK1,LGI1,L3MBTL4,CHGA,PLEKHB1,LHX2,DLGAP3,FAM189A2,IGLON5,PCYT1B,COL9A1,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,TENM4,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,PLXNA4,FAM169A,PPP1R16B,PLCXD3,KIF26A,LONRF1,RIMS3,BRINP1,CHRDL1,HS3ST4,CALN1,SLC25A18,FAM78B,SEMA3D,EFNA2,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,CSPG5,B3GAT1,TBR1,MEGF10,GABRA1,HRASLS5,GABRA5,CHL1,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,GPM6B,TMEM121B,CECR2,TMEM179,HAS2,IGSF21,C1orf94,IGFBPL1,C9orf129,USP51,SHISA6,CELF5,NKD1,LIX1,TUBB2B,C2CD4C,CDH20,KCND2,KCNF1,CLVS2,KCNQ2,KIF5C,KIT,LRRC4B,CAMK2N2,FGFBP3,MATK,MATN3,MOBP,SCG3,DDX25,MYT1,NNAT,NODAL,SLC10A4,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PDZRN4,MAGEL2,PACSIN1,FA2H,FAT3,PPP2R2B,PPP2R2C,RASGEF1B,RAB39A,RELN,LAMA1,MDGA2,ELOVL2,STK32A,PTPRD,NKAIN1,TMEM255A,SLC25A48,ACSS3,FAM184A,KHDRBS2,RET,PRIMA1,MRAP2,HUNK,RXRG,SALL1,TMEM200C,SH3GL3,SLC1A6,TMEM132D,INAVA,CABCOCO1,SOX3,SOX10,LHFPL4,BEX1,MCF2L2,STOX1,ZFR2,NUDT10,ADAMTS17,TMEM150C,COBL,SYT4,TBCEL,KLHL4,FAM189A1,ARHGAP9,PCDHA6,PCDHA3,PCDHA2,TEX15,LEFTY2,GALNT17,ENHO,TMOD1,FAM124A,ANKRD24,PIK3R5,SEZ6L,IL34,TRPM2,CA14,ANO5,TUBB2A,RPRM,VIPR2,RBFOX3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,PLPP4,ANKS1B,MEIS3,CADM2,SHD,RGMA,STOX2,GAL3ST3,WNK3,PLSCR4,AP3B2,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.19E-08 2.14E-04 3.53E-07 3.22E-06 89 311 "ADCY2,PNMA8B,SORCS2,ALCAM,ARHGAP20,LTBP4,GPAM,TMEM263,CACNA1G,CACNA2D1,ISPD,ARHGEF25,CBLN1,REPS2,SLIT2,CNTFR,ZNF521,TENM4,MICAL2,ATRNL1,VCAN,MYADM,RIPOR2,ARMCX2,ZEB2,DNM1,EDNRA,SEMA3D,EGFR,EPB41L2,LRRC17,EYA1,FABP7,DLC1,FLNC,SEPT9,GFRA2,FREM1,GHR,GLI2,GRIA4,PRDM5,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,LAMA2,MEIS1,NCAM1,ZC3H12B,NEFM,NNAT,PCDH9,PCSK5,PDGFRA,PLTP,FAT3,SH3KBP1,LRRN3,LAMA1,PTCH1,PTN,TMEM260,ZIK1,PTPRD,PYGM,TUG1,RAVER2,ROBO2,ARMH4,MEG3,SATB1,PKNOX2,ARFGAP1,PALLD,ZCCHC24,SULF2,SYNE2,PJA1,PSD3,TGFBR3,HHIP,ASXL3,TNS1,TPM1,TMEFF2,PLEKHH2,STOX2,ST8SIA2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_1000 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.35E-08 2.22E-04 3.66E-07 3.33E-06 210 904 "ASPHD1,ACHE,CSMD3,GALNT16,RNF157,ADCYAP1R1,MTUS1,LRRC7,ALAD,LTBP4,C6orf89,APBB1,APLP1,VAT1L,CPNE5,SLC7A14,ARHGDIG,CADPS,CHID1,CADM3,KIF1A,ADAM23,TTC9B,ADGRB3,NRP2,C1QC,CACNA1G,RUNX1T1,INA,DCLK1,LGI1,LARGE1,CHGB,RAB33A,CLTB,PICK1,CNTFR,FAM171B,PNKD,CREB5,CRMP1,CLIP3,FEZ1,VCAN,PLXNA4,SDC3,NRSN1,ECE2,TOX,SCRN1,BRINP1,B3GAT3,SV2A,DLG2,DLG4,GRIN3A,DNM1,DPP6,FIS1,EBF1,EDNRA,EDNRB,CACNG7,ELAVL2,ELAVL4,BSCL2,LRRC17,ERBB2,SPEG,CEND1,EYA1,FABP7,TUBA1B,TUBB3,TUBB4A,EFEMP1,FCGRT,FDFT1,FGF13,FLNC,DPYSL4,TMEM107,ERGIC3,NSG1,TPPP3,TVP23A,FYB1,PHYHIPL,GAP43,SYT17,IGSF5,GFRA1,GFRA2,FREM1,C1QL1,GLI2,GLRB,PCSK1N,KCNMB4,GNAO1,GNG3,GP1BB,B4GALNT4,TUBA1C,STMN2,GRIA2,GSTM5,CELF3,ACOT7,HPSE2,DISP2,LIX1,TUBB2B,KIF5C,KLC1,L1CAM,LMO2,SYTL4,LSAMP,MAP6,MATN2,MEIS1,MMP16,COMMD5,CCDC80,ADAM22,SCG3,TAGLN3,DDX25,MYH3,NCAM1,IDNK,NEFM,NELL2,NFIX,NNAT,NME4,NPY,NOVA1,NPR2,PCBP3,NTRK2,NTRK3,DDR2,CLDN11,PDGFRA,SLC10A4,PENK,PFKP,PGAM2,GDAP1L1,SERPINE2,SMOX,FXYD1,PCDH18,PLTP,PMP22,PRRX1,FAT3,POLR2F,NKAIN4,MAPK10,PRPH,MASP1,NDUFS7,EML5,TMEM255A,FAT4,TSPY26P,RET,ROBO2,ARMH4,HUNK,RTN1,S100B,FAM19A1,SCG5,SNAP25,SNRPN,SCN3B,SST,EPB41L3,SULF2,SEPT3,SYT11,NUDT10,ADAMTS17,SYP,SYT1,ASTN2,ADGRL3,CUX2,PCDHB9,TF,THRA,TMEM9,TNNT1,TPM2,KCNE5,SSBP2,TMEFF2,CADM1,SLC35A4,UCHL1,MTCH1,VLDLR,ZNF32,DPYSL5,STMN4,MVB12B" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 4.38E-08 2.24E-04 3.68E-07 3.35E-06 41 107 "ACTN2,ADCYAP1R1,KIAA1324,ARRB2,ATP1A3,ATP6V1G2,CACNA1A,THSD7A,COG1,NECTIN3,PLCH2,DGKB,EFNA3,EPHA5,ATP8A1,DLL3,TMEM8B,PPARGC1A,GRIK4,GUCY1B1,HPCA,KCNN3,KIT,BCO1,PLP1,MTRF1L,TRHDE,MASP1,GDPD2,FEZF2,RFX4,SLC1A2,SLCO1A2,SPATA7,C3orf70,PRMT8,RBFOX3,TRIM9,LRP8,TMEM163,PRRT4" Coexpression Atlas facebase_RNAseq_e10.5_MaxArch_2500_K3 facebase_RNAseq_e10.5_MaxArch_2500_K3 Gudmap RNAseq 4.77E-08 2.43E-04 4.00E-07 3.64E-06 277 1254 "ACLY,ARID1A,SLC12A5,KIAA1211,KIAA1324,SEMA6A,CEP126,FAM135A,DOC2A,LRCH2,APC,UPRT,BCAS1,LGR5,CDC14B,ARHGAP5,MARCH3,ASPH,PTCH2,ATM,BCHE,BLM,ZNF599,PROM1,KSR1,BMP7,ST3GAL5,CACNA1G,GPC2,CA4,CA12,CACNA1A,CACNB2,HAP1,PTBP2,PRC1,CDK11B,LRBA,SEPT7,CDC27,CCPG1,CRLF1,ADGRG1,SLIT2,C4orf33,NIPBL,AKAP7,IQCK,PCYT1B,CABP1,SLC4A7,AHCTF1,CREB5,HAPLN1,CLIP3,CRYM,SNCAIP,FEZ1,IPCEF1,VCAN,FAM169A,DZIP3,PHF14,PNPLA8,GREB1,CFAP61,FGFR1OP2,KATNAL2,TOX,CENPL,EARS2,LIN54,PITPNC1,KIAA0753,GSDME,DDX46,MTX3,FAM107B,DNM1,USP3,CASP8AP2,ACOT8,DTNA,EDNRA,OPTN,EGR3,LPAR6,EIF4G2,EIF5,PLEKHO1,EPB41,ANKRD13B,SLC43A2,SRRM1,CEP85L,ETV1,CEND1,EYA1,WAC,CORO2B,ZSCAN30,FDFT1,FECH,CAMSAP1,SEC23B,ZMYND15,SGIP1,NOP56,SYT3,SMC2,STAU2,TMEM151A,KIAA1841,GFRA2,FREM1,PCDH17,NTNG2,RND1,DBF4,GLI2,GLRB,TOX3,ZNF638,CBX1,EML4,GRK4,CNTRL,PRDM5,CIT,KIF3A,MFSD2A,PSIP1,FAM107A,ADAMTS6,ATOH8,BACH2,HPCA,HSF2,HSP90AA1,SMAP1,ICA1,IGF1,DOCK7,LRRCC1,LIX1,ZNF385B,KCNJ16,KIF2A,KIF5C,HECTD2,SMAD9,GPR155,MAP2,MBNL1,MEST,MIA2,MID1,AFF1,N6AMT1,LINC00672,TCEAL5,NASP,NEFM,NFE2L2,CNOT4,NPY,CLEC9A,ODF2,CLDN11,P2RY1,PDE3B,PDE4D,ENPP2,TMOD2,FAM98B,CDK14,RETREG1,GPSM2,PLP1,PCDH18,PRRX1,MAPK8,LRRC49,CNTLN,MTMR10,SPDL1,ZIK1,NKAIN1,CCDC40,RAP1GAP,ARID4A,RBBP8,VEPH1,REV3L,ERI2,FIGN,RFX3,RNASEL,SETD5,MYH14,ACER3,KCNIP3,CLIP1,SELL,SFPQ,SCG5,KIF21A,CHD9,CNKSR2,ST3GAL3,ST8SIA1,DZIP1,ANKRD6,PPP4R3A,DHX30,RUFY2,PKNOX2,CCDC88A,ZNF334,TET1,SMARCC2,SMARCE1,IFT122,MBD5,PDZRN3,TNIK,SOX5,ERC1,ARHGAP26,RBM26,TAB2,SAMSN1,SST,ZSCAN29,SULF2,SEPT3,SYNE2,VPS13A,ANKRD12,TAL1,SATB2,ZEB1,TCF12,NSD1,SIRT1,CHST8,C18orf54,AP4E1,TMPO,R3HDM1,PIK3R5,C9orf85,TPM4,PDSS1,STXBP4,TRPS1,TSC1,USP1,KLC2,XPO1,ZFP37,ZNF711,ZNF23,AGMO,SLC26A10,ZNF184,SMARCAD1,MAP3K12,EMSY,LRP8,EVI5,TUBA1A,WNK3,KLHDC1,NETO2,ST8SIA2,SENP7" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k3 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.85E-08 2.48E-04 4.06E-07 3.70E-06 75 249 "PNMA8B,PKP4,ATP2B1,BACH1,IL33,RUNX1T1,ZNF445,SRSF11,SLIT2,PLAA,COL4A5,FAM171B,CSF1R,GAPVD1,AIF1L,ZEB2,ZC3H11A,CDON,APH1A,EIF4G1,EPB41L2,SRRM1,TMEM132C,SEMA6C,ANKFY1,SMC2,APOPT1,SRCAP,LPAR4,PARD3B,GRM7,GSN,RASSF8,HAS2,KLF12,MIER3,KCND3,MAP4,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,NASP,OCRL,PCDH9,GPR85,PIK3R1,PLEC,PRRX1,KANSL1,MAPK8,C1orf54,RNASEL,TMLHE,MEG3,ATXN2,TRA2B,CHD9,TET1,ZC3H13,TROVE2,PRRC2C,SYNE2,AHCYL2,CBX5,R3HDM1,TRPS1,SSBP2,UBE3A,FLRT2,NAV2,SNX27,GAN,SENP7" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.00E-08 2.55E-04 4.17E-07 3.80E-06 94 335 "ADD3,ALCAM,CCDC146,LRRC4C,ARHGAP5,CADPS,ASCL1,CCDC181,MPDZ,BMP7,SPAG9,PRC1,SEPT7,CDO1,JAM2,IGDCC3,NECTIN3,TENM4,TOX,DCC,MAGI2,SGSM2,CHRDL1,DTNA,EEF1D,EFNB3,FAM13A,EN2,ADGRV1,FAM198B,FABP7,FDFT1,FGFR3,CAP2,SMC2,PDLIM5,RND1,GPM6B,HMGB1,CFAP126,HES5,ITGA7,KIF5C,MAP6,MEST,KITLG,CCDC80,MSI1,MXI1,NASP,NELL2,PDE3A,ENPP2,PLCL1,PLTP,FAT3,NXPH1,POU3F2,LRRN3,VSTM2L,HYDIN,PTPRO,PTX3,ARID4A,ZMAT4,RFX2,RFX3,RFX4,NEK11,SALL1,SCN7A,HES6,SFPQ,PUF60,PPP1R9A,EPC1,LIMCH1,MYO16,SOX2,SPART,ITPRID2,SULF2,SYNE2,TCF12,PSD3,CRTC1,CCDC173,DNAH7,TMPO,TRPS1,PPIL6,TRIM9,LMAN2L,IFT88" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_500 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.05E-08 2.57E-04 4.20E-07 3.83E-06 51 147 "ADORA1,BCAR3,AMH,SEMA7A,ARHGDIG,CADPS,BCHE,SYNJ2,CACNA2D2,CLU,CLTB,COL9A3,MAGED1,CST3,PPP1R16B,JAKMIP2,PLPPR4,RCAN1,DTNA,MRO,PLXNC1,CERCAM,EPS8,ERBB4,REEP2,PTK2B,TUBB3,FGF13,SEMA6C,CSPG5,GATM,GPM6B,PADI2,MYO7A,PAK3,PGAM2,SERPINE2,SCHIP1,RASGEF1B,MASP1,DUSP15,SH3GL2,SLC6A8,EFHD1,TNIK,TACC1,SIN3B,THRA,TIAM1,TRPC3,SGK3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.05E-08 2.57E-04 4.20E-07 3.83E-06 51 147 "ADCY2,SPARCL1,ALCAM,ARHGAP20,LRRC4C,SLC4A4,MYRF,CDH10,SLIT2,CNTFR,AKAP5,ZNF521,TENM4,ATRNL1,VCAN,BOC,SV2A,DNM1,TSPAN5,EDNRA,LRRC17,FABP7,FLNC,DENND2A,GFRA2,FREM1,GUCY1A2,GUCY1A1,TCEAL6,NKD1,MATN2,MEIS1,NCAM1,NEFM,NFIA,NME4,PDGFRA,PCDH18,PRRX1,LAMA1,PTN,TMEM255A,MEG3,SCN2A,PALLD,PEG10,PSD3,ASXL3,TRPS1,FLRT2,VSNL1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.21E-08 2.66E-04 4.31E-07 3.93E-06 21 38 "DPP10,CADPS,CACNA1B,CDH10,CHGB,GRIN3A,ELAVL2,ELAVL4,DNER,STMN2,KIF5C,MAP4,NEFM,CLDN11,NALCN,MAPK10,PRPH,RGS4,RTN1,SNAP25,SCN3B" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN_Overall_Top_40_Genes GSE76381_iPSMoleculeCountsPMLog2 5.21E-08 2.66E-04 4.31E-07 3.93E-06 21 38 "SYT13,ANK3,RUNX1T1,INA,TENM1,EPHA5,NSG2,GAP43,STMN2,HS6ST3,MYO5A,NCAM1,TMOD2,PRKACB,RTN1,SNAP25,SCN3B,VGF,CELF4,STMN4,SCG2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 40 GSE76381_iPSMoleculeCountsPMLog2 5.21E-08 2.66E-04 4.31E-07 3.93E-06 21 38 "SYT13,ANK3,RUNX1T1,INA,TENM1,EPHA5,NSG2,GAP43,STMN2,HS6ST3,MYO5A,NCAM1,TMOD2,PRKACB,RTN1,SNAP25,SCN3B,VGF,CELF4,STMN4,SCG2" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.24E-08 2.67E-04 4.33E-07 3.95E-06 191 809 "ADCY2,KLHL13,PCDH19,OSBPL6,ALCAM,ARHGAP20,PCDH10,FAM135A,DPP10,DGKD,CASK,CADPS,ATP2B1,ADGRB2,ADGRB3,PROM1,BMPR1B,IL33,CA4,CACNA1D,CACNA2D1,CALB1,CANX,ISPD,CCK,LDB2,CD86,DCLK1,CFL2,NRXN3,LY86,CNTN1,COL9A1,CNRIP1,AKAP12,CRYM,SNCAIP,ATRNL1,SIPA1L1,VCAN,ERC2,ZFYVE16,ZEB2,GSDME,SMG7,NTM,KBTBD11,GRIN3A,EDN3,PLXNC1,EIF5,SRPK3,CALCRL,ENO2,EPB41L2,RASGRP2,EPHB1,NCALD,RASL12,MRVI1,HSPA12B,FECH,EFCAB2,DPYSL4,SMC2,DACH2,CGREF1,TVP23A,DKK3,GABRA1,GALC,GAP43,FREM1,PCDH17,GHR,LYVE1,RAB40B,FERMT2,B4GALNT4,GRB10,GRIA1,GRIA4,GRIK2,GRM7,GUCY1A1,HAS2,UBE2QL1,ZHX1,NEGR1,SCIN,IL11RA,TUBB2B,KCND1,KCND3,KCNJ16,LAMA2,LIFR,NCOA7,MATN2,MEIS1,MMP16,COMMD5,CCDC80,MSR1,NCAM1,NDP,NFIA,CNOT4,NRDC,CLDN11,PBX1,PCDH8,PCDH9,PDE3A,GPR85,GNG2,PENK,TMOD2,PIK3C2A,TRHDE,PRRX1,ING3,MBOAT7,FAT3,KANSL1,NKAIN4,PKN2,BCAS3,PTH1R,PTPRO,PTX3,PID1,C1orf54,ZYG11B,REV3L,RGS4,LGI2,SNX22,SYNDIG1,SALL1,MAPK12,LRFN5,HOGA1,SCN7A,HES6,ASRGL1,ST8SIA1,DHX30,RADIL,SLC9A5,CXXC4,SNCA,PALLD,MYCBP2,CLASP2,SAMSN1,STX1A,VPS13A,PLCB1,SYT4,PJA1,CAMSAP2,FAM208A,PDLIM2,MGRN1,ANO4,VWC2,CUX2,PCDHB9,PCDHB3,THBS4,ENHO,ERCC6L2,RBFOX2,TPM2,RGMB,SYNPO2,TRO,SSBP2,TUBB2A,TMEFF2,FLRT2,VLDLR,PROCA1,SPIRE1,MAP3K12,NAV3,GOPC,MSRB3,NETO2,CBLN2" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000_k5 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.43E-08 2.77E-04 4.48E-07 4.08E-06 71 232 "TKTL1,INTS2,NME5,LCORL,LGR5,PDE8B,ASPA,CAPRIN2,DDX3Y,INSYN2B,SYNJ1,ARHGEF7,CACNB2,CALB1,LONRF2,KMT2C,CNR1,GREB1,DOCK4,HDAC9,MAGI2,SACS,DYNC1I1,DRP2,DNAJB6,RASGRP1,KIAA1109,ATP6V1H,ZMAT1,GABRA4,GGT5,AIFM3,MAP7D2,GRK4,ZNF385B,KCND2,MAP4,KITLG,MYO5A,NEXMIF,NELL1,GLIPR1L2,PDPK1,ABCB1,SERPINI1,PLP1,PPP2R5E,FAM120C,LRRTM4,PRCD,FNIP1,TNFRSF19,HSPA4L,SYBU,CPEB4,MYT1L,SOX5,SLC37A2,ANKRD12,DMXL2,DOCK9,CCDC173,TEX15,DNAH7,ACTR6,RASD2,FNDC5,ZNF711,ZNF23,REEP1,PHTF2" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.60E-08 2.86E-04 4.61E-07 4.21E-06 56 168 "ADORA1,HECW2,BCAR3,AMH,SEMA7A,ARHGDIG,CADPS,BCHE,SYNJ2,CACNA2D2,JAM2,CLU,CLTB,PPP1R16B,TOX,JAKMIP2,ELMO1,PLPPR4,RCAN1,GNE,DTNA,MAMLD1,EDN1,MRO,CERCAM,EPS8,ERBB4,REEP2,PTK2B,TUBB3,FGF13,SEMA6C,GPM6B,PADI2,HSD17B1,MYO7A,CLDN11,PAK3,PGAM2,SERPINE2,SCHIP1,RASGEF1B,EPDR1,MASP1,DUSP15,SOX8,SH3GL2,SLC6A8,EFHD1,TNIK,TACC1,SIN3B,THRA,TRPC3,SGK3,NHSL1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.00E-08 3.06E-04 4.94E-07 4.50E-06 54 160 "SORCS2,C1QTNF3,SYT13,CADPS,IL33,RUNX1T1,LDB2,CDH2,CDH10,FAM171B,BOC,SRGAP3,NTM,EBF1,SEMA3D,TMTC1,ELAVL2,CALCRL,EFEMP1,GFRA2,GLRB,RAB40B,GRIA4,UBE2QL1,IGF1,KCND2,MATN2,MEIS2,CLDN11,PCDH8,PDGFRA,PIK3R1,PRRX1,MED1,PTPRD,FAT4,RNASEL,LGI2,MEG3,SATB1,CSRNP3,FAM19A1,NTNG1,MTERF2,MAPKBP1,TROVE2,ANO4,VWC2,TEX15,ZFPM2,ITGB3BP,HHIP,SSBP2,LYPD6" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 6.06E-08 3.09E-04 4.98E-07 4.54E-06 196 836 "EMILIN3,ADCY8,RTL9,DISP3,SEMA6A,SRPX,MARCH4,CACHD1,USP37,CDK10,IGDCC4,SPTBN4,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDK11B,LRBA,CDH18,CDO1,CRLF1,DIS3L,SRSF11,CLTB,FAM149A,COL9A1,COL9A2,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,CLIP3,SNCAIP,SUSD5,ATRNL1,DZIP3,PHF14,BOC,ARHGAP24,DGKB,DGKG,GSDME,DDX46,CCDC3,GRIN3A,DNM1,USP3,DUSP9,ABCC9,SYT15,ELN,HSD17B14,EPB41,EPB41L1,LRRC17,RAB9B,DENND4A,HSPA12B,TMEM132C,FCGRT,FDFT1,TESK2,SCARA3,SGIP1,AFF2,SYT3,NBEA,ZCCHC17,SMC2,TRIM16,STAU2,TMEM151A,TVP23A,ZMAT1,DKK3,TRAF3IP2,JPH4,CPLX2,NEU3,GFRA2,ZNF276,RAB30,ZNF638,GRIK4,GSN,WIF1,BACH2,SYNPO,ICA1,LRRCC1,LIX1,IL11RA,ITPKB,JAK2,KCNJ5,KHK,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,TM6SF1,SRSF12,CD200,CPNE9,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ODF2,ZNF827,CNTN3,PDE1A,PDE3A,PDE4D,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,ACSS3,IQSEC3,FAT4,RAP1GAP,RAP1GDS1,BEND5,RBBP8,ZFHX4,MRAP2,LRRK2,DGLUCY,ATXN1,SFPQ,SH3GL3,DOCK10,NTNG1,ST6GAL1,CNKSR2,DZIP1,PREX2,DHX30,SLC8A1,CCDC88A,SMARCC2,LIMCH1,PDZRN3,DOP1A,BDP1,UHRF1BP1L,ARHGAP26,CDK19,EPB41L3,NKAIN2,ZSCAN29,ARHGEF9,ADAMTS17,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ASXL3,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,USP1,TSPAN11,ZNF708,ZNF32,ZNF184,PMEPA1,MRPL47,CERS6,ADAMTS10,SSPN,KLHDC1" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_1000 dev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.12E-08 3.12E-04 5.02E-07 4.57E-06 195 831 "CCDC85A,ADORA2A,HECW2,NR0B1,ADGRF5,SPARCL1,SEMA6A,BIN1,SEMA7A,LCORL,MAP4K3,APAF1,APBB2,UPRT,SHROOM2,ARRB1,MARK4,DOCK11,ADAM15,NRP2,PROM1,ARHGEF7,C1QC,LDLRAD4,THSD7A,CALM1,SPAG9,LDB2,FMNL3,SCARB1,CD38,ARHGEF2,LRRFIP1,MAGI1,MS4A7,JAM2,TAOK2,ABCG2,TMEM184B,MAP4K4,LY86,ZNF521,CDC42BPB,CRMP1,HAPLN1,CSF1R,PPP1R16B,USP6NL,CX3CR1,CYBB,DOCK4,TOX,KIAA0513,RASSF2,GIT2,PITPNC1,ELMO1,CEP170,SACS,FAM107B,GNE,ECM2,EBF1,EDNRB,ATL1,SH3GLB1,MBNL2,LPAR6,PLEKHA1,CALCRL,PLEKHO1,RASGRP2,STX2,DENND4A,NRN1,FAM198B,CORO2B,DLC1,CHST15,KIAA1109,FLT1,PDLIM5,TRIM16,ST6GALNAC3,FYB1,FYN,NEK6,GAP43,INPP5K,GATM,PCDH17,GGTA1P,HPGDS,GLUL,LILRB4,LPAR4,RAPGEF4,STMN2,GRIA2,MAP4K5,MAEL,NCKAP1L,ZDHHC15,HTR2A,ICA1,IGF1,TUBB2B,ITPKB,KIT,INSYN2,LMO2,TM6SF1,MEF2C,MEST,KITLG,LAYN,MYO6,CLEC9A,OPHN1,PALM,PDE2A,PDE4B,PDE4D,GNG2,ABCB1,PLCL1,SPATA6,DRAM2,PPP2R5C,SYTL2,SNRK,MDGA2,PTK2,PTPRB,PTPRG,TMEM255A,C1orf54,FAT4,KCTD17,PRR5L,RPS6KA2,SEMA6D,SCN2A,RASA3,SGK1,FAM102A,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,SPP1,UNC5B,PEG10,ZNF423,ARHGAP26,SPTAN1,COLGALT2,SAMSN1,THSD1,RGL1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,ZEB1,DOCK9,TEK,TF,TIE1,HEY1,TJP1,TLR4,TRPC3,DCBLD1,RFTN2,TUBB2A,WIPF1,ZNF711,SLC26A10,PMEPA1,GDPD5,STOX2,ADAMTS9,NAV3,FAM13C,DOCK8,JMJD1C,MSRB3,NHSL1,ZDHHC20,SPATA13" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_1000 kidney_P3_CapMes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.23E-08 3.18E-04 5.10E-07 4.65E-06 179 750 "ABR,NCKAP5,NDRG2,KLHL32,RNF157,ADORA1,ZNF608,MTUS1,PCDH19,TXNDC16,ALCAM,CEP126,AMPH,CACHD1,VAT1L,ADAM23,BARD1,BCL7A,BLM,PROM1,BMP7,CACNA1G,CA4,CA12,CACNA2D1,CACNB4,MAP7,CDH2,SOCS6,SLIT2,CLU,FAM19A5,CNTFR,CLIP3,CRYM,SNCAIP,TENM4,SIPA1L1,VCAN,KIAA0040,CTH,GREB1,USP6NL,ECE2,CENPL,SCRN1,SPOCK2,GSDME,SNAP91,SV2B,RAB39B,EDNRA,HEYL,ELAVL4,EMX2,HSD17B14,EPB41,KCNMB2,ETV1,EYA1,ST3GAL6,FCGRT,POLR1B,FGFR1,MAD2L2,SCARA3,MEX3B,CAP2,FOXM1,TRIM16,KHDRBS3,STAU2,MPP6,MTHFD2,IGSF5,FAXC,GFRA1,GLRB,TOX3,KDM2B,PSRC1,ADGRA3,TDRKH,CECR2,PCLO,GRIK4,FAM107A,GUCY1B1,HAS2,NEGR1,HTR2A,SLC6A17,KHK,KIF5C,LSAMP,GPR155,CLEC18A,MAT2A,TM6SF1,MEIS2,POC1B,MSI1,ADAM22,MYCN,MYO6,NCAM1,NELL1,NFIX,NME4,NOS1,NPY,CNTN3,PRTG,PDE3B,ENPP2,PENK,SMOX,PLXNB1,PMP22,PMS2,PRRX1,SDK2,FAT3,PKIA,MDGA2,ELOVL2,SPDL1,PTN,PTPN13,ZCWPW1,RBBP6,RAVER2,ROBO1,ROBO2,TMEM100,GLDN,PRR5L,HUNK,CCDC112,SALL1,SCN2A,ASRGL1,SH3BGR,SH3GL3,CNKSR2,SLC1A3,SEPHS1,SLC12A2,SLC15A2,ATF7IP,GKAP1,SORCS3,KIF13A,CMTR2,PDZD2,SOX11,SP4,ELOVL4,NUDT10,TMEM150C,TACR1,CAMTA1,CUX2,TRIM2,PCDHB9,ARHGEF12,AKTIP,HEY1,HEY2,TMOD1,TRPS1,CADM1,PLEKHH2,LAMP5,SLC38A1,ADAMTS9,FZD3,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.31E-08 3.22E-04 5.16E-07 4.70E-06 120 459 "ABHD6,ACTN2,ADCY2,SLC24A4,HECW2,KIAA1324,SMIM17,SRPX,CEP126,ARHGAP20,MARCH4,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,C1QC,LDLRAD4,CAMK2A,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,DGKG,TIAM2,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,ELN,HSD17B14,RAB9B,EPS8,SEMA6C,SGIP1,DLL3,ABLIM2,FYB1,DKK3,ARPP21,TMEM8B,GHR,LYVE1,NTNG2,GLRB,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,ICA1,LRRCC1,SCIN,IL11RA,ZNF385B,KCNA6,KLHL23,GPR155,MID1,MOBP,CPNE9,MYH3,NEXMIF,TCEAL5,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,PRIMA1,MYH14,LRRK2,DGLUCY,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,CCDC92,SLC1A2,SLC6A9,ARHGAP26,IQSEC2,C11orf87,NKAIN2,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,KCNE5,PMEPA1,CADM2,LRP8,PCDH15,DPF3,PRRT4" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.54E-08 3.34E-04 5.34E-07 4.86E-06 62 194 "EMILIN3,USP31,TAOK1,ANK3,APAF1,APC,PHYHD1,LGR5,CASK,BCHE,BMP7,CACNA2D1,CANX,VCAN,MFAP3L,ARNT2,KBTBD11,DPYSL2,EDNRA,EDNRB,HIPK3,SEMA3D,ETV1,DLC1,CELF1,IQGAP2,GFRA1,PCDH17,GHR,PPARGC1A,FERMT2,GRIA2,GUCY1B1,KLF12,ZDHHC15,KITLG,PPM1L,MKLN1,NFIA,PDE3A,PDGFRA,PIK3C2A,PRRX1,FAT3,KANSL1,REV3L,SETD5,TNFRSF19,ZHX3,SMOC1,EPB41L3,NEK4,FBXW11,TBL1X,NSD1,HHIP,ERCC6L2,RBFOX2,RGMB,TRIO,TRPS1,MSRB3" Coexpression Atlas gudmap_developingGonad_P2_epididymis_500_k2 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.74E-08 3.44E-04 5.49E-07 5.01E-06 48 136 "PNMA8B,ARHGAP20,PKP4,ATP2B1,BACH1,IL33,RUNX1T1,ZNF445,SRSF11,PLAA,COL4A5,AIF1L,ZEB2,ZC3H11A,EIF4G1,EPB41L2,SRRM1,SMC2,APOPT1,LPAR4,RASSF8,MAP4,CHIC1,MEIS1,MEIS2,SAMD5,PCDH9,PIK3R1,PRRX1,FAT3,MAPK8,C1orf54,RNASEL,TMLHE,MEG3,TRA2B,TET1,ZC3H13,TROVE2,PRRC2C,SYNE2,CBX5,SSBP2,UBE3A,FLRT2,VLDLR,GAN,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k2 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.80E-08 3.47E-04 5.53E-07 5.04E-06 94 337 "ACTN1,ADCY5,C1QTNF3,ANK1,NT5C3B,KIAA1614,DACT3,ATP1A2,ATP2A2,MYOM1,BCHE,NRP2,NIPA1,CA4,CACNA2D1,NGB,CAMK2D,NEURL1,CFL2,RAB3C,AKAP5,SV2B,RABGAP1L,CPEB2,DTNA,ABCC5,ABCC9,SH3GLB1,CERCAM,SRPK3,EML1,PLEKHO1,NCALD,SPEG,MRVI1,FCGRT,FGF12,PRKAG2,CAP2,DKK3,GABBR1,ADAMTS8,BVES,HNMT,SHISAL1,IL6ST,ITGA7,ITPKB,KCNB1,KCND3,KCNF1,KCNH2,KLHL23,KCNMA1,IL17D,MMP17,MYH6,NPTX2,PDE4B,PDE4D,TMEM38A,SCHIP1,PRKAB2,PRKCB,PTGR2,RYR3,SCN2A,STUM,SH3BGR,SH3GL3,FHOD3,ABLIM3,RIMS1,TNIK,FNBP1,RAP1GAP2,SRPK2,INKA2,ARHGEF9,SYN2,TEX15,ENHO,NACC2,TPM2,SYNPO2,PPIL6,MICAL1,RBFOX3,RGS7BP,FAM13C,ACTR3B,ADAMTSL3,MSRB3,SSPN" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_500 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_500 FaceBase_ST1 7.20E-08 3.67E-04 5.85E-07 5.33E-06 95 342 "SDE2,FZD9,PCDH19,NR0B1,APBA2,CPNE5,ASCL1,SNAI3-AS1,FGF17,CA4,CBLN1,CCNT1,USP2,INA,CDC25B,JAM2,RAB33A,NMT2,FAM189A2,FAM19A5,CNTFR,FEZ1,IST1,SCRN1,JAKMIP2,EFNA2,PHF20L1,ELAVL3,PCOLCE2,EN2,DENND4A,REEP2,FABP7,TUBB4A,SPSB4,DPYSL4,CELF1,TPPP3,PHYHIPL,NKX6-2,TOX3,PCSK1N,PRRC2B,RNF165,MFSD2A,SOX21,UBE2QL1,IGSF21,TOX2,USP51,NKD1,HES5,TUBB2B,LMO1,MEIS1,POC1B,AFF1,MT3,SCG3,MYO9A,PAK3,PALM,PAX6,PCDH9,SLC25A23,NECAB2,FAT3,POU3F4,PRKCZ,ANKHD1,ELOVL2,FEZF2,RDX,PBRM1,ROM1,ARMH4,TNFRSF19,HSPA4L,KIF21A,CCDC88A,ARFGAP1,SOX2,SEPT3,SYT11,WSCD1,TCF12,TMEM121,TRH,TRPS1,RPRM,FAM181B,RBFOX3,WNT7A,ZBTB16,SNX27" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500 dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.44E-08 4.31E-04 6.84E-07 6.24E-06 108 404 "FMNL2,SLITRK1,HECW2,KLHL13,NR0B1,ARHGAP20,KCNT1,CDC42BPA,APOC1,LGR5,PPP4R4,IGDCC4,NUMB,ATP2B3,DST,ST3GAL5,CACNB2,CALB1,SLC16A4,DCLK1,MAGI1,ADGRG1,CHRM4,PLXNA4,DOCK4,DAPK1,CDON,DRP2,RASGRP1,KLHL5,PLXNC1,TMEM35A,EMX2,MTSS1L,NRN1,AFF2,CAMKK2,GABRA4,GABRB1,GALC,PCDH11X,GPR37,PACSIN2,SHISA6,IGF1,LRRTM3,KCND2,KCNH1,KLHL23,NCOA7,MATN2,MEIS1,KITLG,AFF1,CCDC80,CTNNA3,MTR,MYO9A,NELL2,NFIA,NUCB2,PDE1A,SERPINI1,PIK3C2A,PCDH18,LRRN3,PPP3CC,GDPD1,PTPRG,REV3L,ZFHX4,TMEM206,RPS6KA2,LGR4,HUNK,SEMA6D,TNFRSF19,STUM,MRAS,RASA3,WDR37,SLC4A3,SNCA,KDM3A,UHRF1BP1L,SMOC1,LRRC4,ST5,ADGRL3,DOCK9,OBSL1,TEX15,DNAH7,ZFPM2,ACTR6,TNNT1,TRPS1,FNDC5,TST,PCDH20,ELFN1,LYPD6,ADAMTS9,SIGLEC10,NAV2,WNK3,FRMD6,DPF3" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K2 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 8.69E-08 4.43E-04 7.04E-07 6.41E-06 152 618 "ACTN2,METAP1D,ADCY2,SLC24A4,HECW2,TBC1D14,KIAA1324,SORCS2,SMIM17,ARHGAP20,GAS7,APOC2,LGR5,ZFYVE28,ARRB2,PDE8B,ATP1A3,MTMR9,ADGRB2,BARD1,NRP2,ZNF599,KSR1,C1QC,IL33,LDLRAD4,CFAP410,CA12,CAMK2A,CAMK2B,REPS2,KCNAB3,CCPG1,CLU,SLC24A2,VAX2,BAG4,CREM,HAPLN1,CRYBB1,CSF1R,MICAL2,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,RASGRP2,SEZ6,EPS8,NCALD,CDKL3,PTK2B,CORO2B,ZMYND15,DLL3,ADGRA1,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,NTNG2,GLRB,GNG4,GOLGB1,ADAP1,GRK4,GRIA1,TMEM25,GUCY1B1,KNDC1,SCIN,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,CPNE9,BCO1,MYH3,MYO6,NEXMIF,NELL1,NPR2,OPCML,ETFRF1,PDE4B,PDE4D,ENPP2,PDPK1,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,GDPD2,STRC,RAB3IL1,PID1,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,MORC4,PRIMA1,MYH14,KCNIP3,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,CCDC92,SLC1A2,SLC6A9,SLCO1A2,INAVA,DOK5,IQSEC2,C11orf87,SAMSN1,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,LEFTY2,TMOD1,LRRC24,KCNE5,FLRT2,MICU3,EML6,LAMP5,CADM2,LRP8,PCDH15,DNAH10,DPF3,PRRT4" Coexpression Atlas GSM605840_500 "Plasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3" "Immgen.org, GSE15907" 8.75E-08 4.46E-04 7.07E-07 6.44E-06 109 409 "CPNE2,ABHD6,FMNL2,SNX30,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ARHGAP5,ASPH,ZBTB10,ATP1A3,CACNA1E,DDR1,CD38,STOML1,FADS2,LY86,MAGED1,ZNF521,ATRNL1,CST3,CTNND2,RUBCN,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,SIRPA,ZEB2,SRGAP3,RABGAP1L,GNE,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,CHST15,FGR,TMEM107,HVCN1,AK8,FYN,NEK6,GPR162,GPM6B,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,ADAM11,LDLRAD3,MEF2C,MYO5A,P2RY13,ZC3H12B,CLEC9A,NUCB2,PGAM2,PLTP,CDIP1,PACSIN1,PTAFR,TMEM231,ROGDI,ZDHHC14,FOXRED2,SCN3A,IL17RB,SELL,ITSN1,PPM1E,ST8SIA1,BTBD3,CCDC88A,ZCCHC24,TEX2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,TCF7L2,CYB561A3,ATP13A2,SLC44A1,TNS1,TPD52,VAV2,P2RY12,LAT2,LRP8,EVI5,SIGLEC10,TMEM163,PLD4" Coexpression Atlas ratio_EB_vs_SC_500_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 8.76E-08 4.47E-04 7.07E-07 6.45E-06 64 204 "ASCL1,DACT3,MYRF,CDK5R2,LGI1,LHX2,CNTFR,DCC,CCDC3,EDN3,ELAVL3,ELAVL4,ERBB4,TMEM132C,ZIC4,ZMYND10,NSG2,PHYHIPL,ILDR2,FREM1,GHR,STMN2,GRIA2,C1QL4,CELF3,SCRG1,LIX1,SCRT2,INSM1,C1orf194,LRP1B,MEIS2,RSPO2,NELL1,NHLH1,NTRK2,OLR1,PENK,PDZRN4,POU3F2,PRPH,PTH1R,RFX4,ZFHX4,LINC00461,SOX6,SLIT1,SNAP25,ENKUR,CLSTN2,SST,CNTN2,TF,ASXL3,RIMBP2,TRH,FAM181B,ZIC1,STMN4,ADAMTS9,SCG2,SLC17A6,SLC39A12,FAM181A" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k5 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.04E-08 4.61E-04 7.28E-07 6.64E-06 60 187 "EMILIN3,ADRB2,TMEM263,ATP2B1,MYOM1,RAB3C,KIAA1549L,CNTN1,COL9A1,VCAN,PLCXD3,ZEB2,RABGAP1L,RGS17,DCTN4,EPHA5,NCALD,ETV1,RASL12,CAP2,SORBS1,PDLIM5,PNMA2,DKK3,MEGF10,GFRA2,FERMT2,PRUNE2,RBPJ,KCNK2,KCNMA1,LIMS1,HECTD2,MBNL1,IL17D,NPTX2,NTRK2,CNTN3,PCDH9,NALCN,DIRAS2,LGI2,KCNIP3,ATXN1,SH3BGR,SH3GL2,SH3GL3,RIMS1,TNIK,SMOC1,SYT1,SYNE1,HHIP,RASD2,TPM2,SYNPO2,TRPS1,SSBP2,RBFOX3,MSRB3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.66E-08 4.93E-04 7.77E-07 7.08E-06 112 424 "KLHL13,NR0B1,ARHGAP20,CACHD1,LRRC4C,PPP4R4,TMEM108,MYRF,CACNA2D1,CALB1,RUNX1T1,CBLN1,CDH10,DCLK1,SLIT2,CNTFR,ZNF521,HAPLN1,CLIP3,TENM4,ATRNL1,VCAN,PLXNA4,DOCK4,DAPK1,ZEB2,SV2A,DNM1,DRP2,EDNRA,PLXNC1,EMX2,NRN1,ABCA8,FABP7,EFEMP1,FLNC,AFF2,NOP56,ZMAT1,GABRA4,GAP43,FREM1,GHR,PCDH11X,GUCY1A2,GUCY1A1,TCEAL6,NKD1,KCND2,KLHL23,MATN2,MEIS1,MEIS2,KITLG,MMP16,SESN3,CCDC80,MTR,TCEAL5,NCAM1,NEFM,NFIA,NNAT,PDE1A,PDE3A,PDGFRA,CDK14,SERPINI1,PIK3R1,PCDH18,PRRX1,FAT3,SYTL2,PTN,TMEM255A,RNASEL,ZFHX4,ROBO2,TMEM206,LGR4,HUNK,CCDC112,DOCK10,DZIP1,SLC1A3,SLC4A3,PALLD,ZCCHC24,KDM3A,UHRF1BP1L,PEG10,SMOC1,ADGRL3,KLHL4,CUX2,PSD3,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,TNNT1,TRPS1,TMEFF2,FLRT2,PLEKHH2,PCDH20,ZNF711,LYPD6,WNK3,DPF3" Coexpression Atlas GSM854297_500 "Plasmacytoid, DC.pDC.8+.MLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.00E-07 5.11E-04 8.04E-07 7.33E-06 109 410 "ABHD6,FMNL2,SNX30,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ARHGAP5,ASPH,ATP1A3,SEC11C,ZNF599,CACNA1D,CACNA1E,DDR1,CD38,STOML1,FADS2,LY86,MAGED1,ZNF521,CST3,CTNND2,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,SIRPA,ZEB2,SRGAP3,RABGAP1L,GNE,ARRDC4,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,CHST15,FGFR1,FGR,PRKAG2,HVCN1,AK8,NPTN,FYN,NEK6,GPM6B,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,ADAM11,LDLRAD3,MEF2C,PPM1L,MYO5A,P2RY13,CLEC9A,NUCB2,PLTP,CDIP1,PACSIN1,PTAFR,TMEM231,ROGDI,ZDHHC14,SCN3A,IL17RB,SELL,ITSN1,PPM1E,ST8SIA1,CCDC88A,ZCCHC24,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,KIAA0930,CYB561A3,ATP13A2,SLC44A1,TNS1,TPD52,C9orf85,VAV2,P2RY12,LAT2,LRP8,EVI5,SIGLEC10,TMEM163,PLD4,RGS7BP" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.00E-07 5.12E-04 8.04E-07 7.33E-06 65 209 "USP31,OGT,APC,MIER1,RNF182,BMP7,CDK5R1,CACNA1D,CANX,FOXN3,SUSD5,VCAN,ZEB2,DNM1,SEMA3D,ETV1,DLC1,FGFR1,SUCO,DKK3,AHCYL1,IQGAP2,GFRA2,GRIA2,CACFD1,RASSF8,KLF12,BACH2,RBPJ,KIF5C,CHIC1,MEIS2,SAMD5,NASP,NFIA,OCRL,CNTN3,OLA1,PRRX1,KANSL1,MAPK8,PTPRG,PTPRO,TMEM255A,RBBP6,REV3L,ROBO2,SCMH1,ZHX3,CLASP2,TROVE2,EPB41L3,VPS13A,CAMSAP2,ADGRL3,CUX2,PCDHB7,ZFP91,ERCC6L2,RBFOX2,RGMB,TRPS1,NAV3,NUP214,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000 FaceBase_RNAseq 1.02E-07 5.20E-04 8.17E-07 7.44E-06 224 986 "ABCF1,ABR,ACTN2,KDM5D,KIAA1211,PCDH19,TBC1D14,TXNDC16,MRTFA,OGT,ANK1,MAGEE2,APOC2,CDK10,ARRB2,DACT3,ASTN1,DDX3Y,BBS2,MPDZ,ZNF599,PROM1,CA12,DIRAS1,HAP1,PTBP2,ARHGEF25,LDB2,FMNL3,CDK11B,LRBA,CRLF1,DIS3L,ADGRG1,COG1,FADS2,NIPBL,PCYT1B,FAM149A,SUMF2,SLC4A8,ACBD5,IGDCC3,PREPL,CRY2,CRYM,PHF14,ARHGAP32,KIAA0586,IST1,PITPNC1,JAKMIP2,PLEKHM1,HP1BP3,CDON,DUSP9,ABCC9,SNX29,WDPCP,EDNRA,SYT15,KLHL5,SUGP2,ELN,EMX2,EPB41,NCALD,IGSF6,CDKL3,ETV1,CLVS1,NSRP1,WAC,TMEM132C,ACSL4,FDFT1,FGF12,FGFR3,MAD2L2,HPCAL4,CAP2,EVL,AFF2,SMC2,UFM1,ZNF605,ST6GALNAC3,B3GAT1,ADGRA1,FYB1,GABBR1,GAD1,C15orf41,MMADHC,ZNF276,TXNL4A,COPS8,KCNMB4,CECR2,PCLO,RFFL,CIT,GSN,MFSD2A,RABL2A,RNFT2,ATG4C,HPSE2,SYNPO,IGF1,LIX1,IL11RA,INSM1,KCNH2,KCNJ5,KIF5C,LAMA2,LRRC4B,LSS,GPR155,MBNL1,SHC3,SRSF12,MID1,POC1B,SESN3,BCO1,RSPO2,NASP,NBL1,NFIA,NFE2L2,NFIX,NNAT,CLEC9A,SMIM11A,NTRK3,OCRL,OPA1,ETFRF1,PCSK5,PDE3A,CCSER2,LRP12,MAGEL2,PILRA,POU3F4,DRAM2,DIRAS2,CYBC1,ELOVL2,PEX2,ZSCAN2,STRC,RAD51D,ARID4A,ZYG11B,REV3L,GTDC1,KIF7,ZFHX4,RNH1,RAVER2,ROBO2,CCDC25,TMEM100,SGSM1,SOX8,KCNIP3,CLIP1,RXRA,LRRTM4,CASC3,KIF21A,DOCK10,NTNG1,PREX2,PEX26,CCDC88A,LIMCH1,SNAP25,MBD5,KIF13A,SPATA7,BDP1,SOX11,ERC1,C11orf87,SRPK2,SULF2,SYNE2,COBL,TAF9,PDLIM2,TCF7L2,WASHC4,SZT2,ARHGEF12,SIK3,HHIP,TIAM1,ASXL3,BHLHB9,TMOD1,TNS1,AMACR,STXBP4,TRPS1,CA14,TTPA,ZKSCAN5,USP1,MTCH1,ZFP37,ZNF184,LAMP5,UPF3A,PMEPA1,EMSY,EVI5,HNRNPA3,ZNF248,NHSL1,SENP7" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.03E-07 5.26E-04 8.25E-07 7.52E-06 70 231 "FMNL2,KLHL13,NR0B1,CACHD1,LGR5,CDC14B,PPP4R4,NUMB,WASF1,CACNB2,CALB1,SLC16A4,DCLK1,CDH18,MAGI1,PLXNA4,NOS1AP,DOCK4,DAPK1,DCT,MAGI2,SRGAP3,DRP2,AASS,EMX2,MTSS1L,ABCA8,AFF2,GABRA4,GABRB1,PCDH11X,BVES,SHISA6,KCND2,KLHL23,KITLG,AFF1,CCDC80,MTR,MYBPC1,NFIA,PDE1A,SERPINI1,PTPN13,REV3L,TMEM206,LGR4,HUNK,RASA3,ST8SIA1,SLC4A3,SOX5,KDM3A,UHRF1BP1L,SMOC1,LRRC4,ST5,ADGRL3,OBSL1,CCDC173,DNAH7,ZFPM2,ACTR6,DAAM2,TNNT1,FNDC5,TST,LYPD6,NAV2,DPF3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_500 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.07E-07 5.46E-04 8.54E-07 7.79E-06 107 401 "METAP1D,ADCY8,USP31,AMPH,ANK3,APC,VAT1L,SFMBT2,SEMA4G,ZSCAN18,ATP1A2,BMP7,OSGIN2,IL33,CACNA2D1,CACNB4,CH25H,FAM19A5,COL9A1,ZFP28,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,KATNAL2,SPOCK2,RAB39B,DYNC1I1,DTNA,HEYL,ELAVL4,TMEM35A,EIF1,CDHR1,EYA1,ST3GAL6,FGF1,FGFR1,SCARA3,CAP2,SGIP1,PRELID3A,DACH2,MEGF10,GABRB3,GFRA1,BRD8,GLDC,KIAA1958,FUT10,CECR2,GRB10,PRDM5,FAM19A2,FAM107A,HAS2,FRMD3,NEGR1,ITIH2,KIF5C,MSI1,MYBPC1,FXYD6,NELL1,OXTR,CNTN3,PRTG,ANKRD16,FAT3,NXPH1,KANSL1,CEP41,PTHLH,PPP2R3C,ENOX1,GAL3ST4,CRTAC1,REV3L,ROBO2,PRR5L,RIMKLA,RPS20,SALL1,MAPK12,ZFP2,SUPT20H,TRA2B,HSPA4L,ANKRD6,SLC1A3,SLC12A2,NEK4,CAMTA1,CAMSAP2,ZFP91,ERCC6L2,TPM2,SSBP2,ZNF184,ZFAND5,INTS3,LRP8,PCBP4,NUP214,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.11E-07 5.68E-04 8.88E-07 8.09E-06 36 91 "PCDH10,VAT1L,RUNX1T1,DCLK1,CDO1,ERC2,TOX,MAGI2,SPOCK3,EGFR,EPHA5,EYA1,TMEM132C,FOXF2,MEGF10,GABRA4,DNER,GLRB,LPAR4,GRIA2,IFI16,MYH3,DDR2,PCDH8,TRHDE,PRRX1,ZFHX4,ROBO1,CSRNP3,ANKRD6,SOX11,TROVE2,UNC5D,ADGRL3,TBX15,PCDH20" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.18E-07 6.02E-04 9.39E-07 8.56E-06 93 336 "NDRG2,ADCY2,ADCYAP1R1,SORCS2,ALCAM,ARHGAP20,LTBP4,GPAM,TMEM263,CACNA1G,CACNA2D1,ISPD,ARHGEF25,CBLN1,SLIT2,NRXN3,CNTFR,SNCAIP,TENM4,MICAL2,VCAN,MYADM,RIPOR2,ARHGAP24,ARMCX2,ZEB2,HEPH,DNM1,EDNRA,HEYL,EGFR,EPB41L2,LRRC17,FABP7,DLC1,FLNC,SEPT9,GFRA2,FREM1,CSDC2,GHR,GLI2,GRIA4,PRDM5,GUCY1A2,GUCY1A1,GUCY1B1,KLF12,HPSE2,KCND3,LAMA2,CHIC1,MMP16,NCAM1,ZC3H12B,NFIX,PCDH9,PDE3A,PDGFRA,FXYD1,PLTP,FAT3,SH3KBP1,LRRN3,SYTL2,LAMA1,PTCH1,PTN,ROBO2,ARMH4,ZNF354C,SATB1,LRFN5,SCN7A,NTNG1,PKNOX2,SLC8A1,ARFGAP1,SORCS3,PALLD,ZCCHC24,CAND2,ZNF423,SULF2,PJA1,PSD3,TGFBR3,HHIP,TPM1,SSBP2,TMEFF2,STOX2,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.18E-07 6.04E-04 9.41E-07 8.57E-06 106 397 "EMILIN3,ADD3,USP31,AP2A2,TBC1D14,TAOK1,ALCAM,OGT,APAF1,APC,PHYHD1,TMEM263,ATP2B1,BCHE,CACNA2D1,CANX,CDH2,SRSF11,PREPL,RBM39,VCAN,DZIP3,TM9SF4,ZEB2,MYEF2,PDCD6IP,DYRK1A,TSPAN5,EDNRB,HIPK3,SEMA3D,EIF4G1,CALCRL,DCTN4,ETV1,DLC1,KIAA1109,SUCO,FLT1,SMC2,PDLIM5,CAMKK2,CELF1,GABRA3,AHCYL1,IQGAP2,PCDH17,GHR,PCDH11X,FERMT2,GRB10,RASSF8,KLF12,ZDHHC15,RBPJ,JAK1,KIT,LIFR,LIMS1,CHIC1,MEF2C,MEIS2,KITLG,MKLN1,MMP16,SAMD5,NFIA,PDE3A,PDGFRA,PIK3C2A,KLHL11,SETD5,RPE,MEG3,CLIP1,ASRGL1,TRA2B,PPP1R9A,PREX2,CPEB4,SOX5,ZHX3,PEG10,SRPK2,CLASP2,EPB41L3,LARP4,MAPK8IP3,PJA1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,UBE3A,WRN,CLDND1,STOX2,SNX27,NUP214,MSRB3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.28E-07 6.51E-04 1.01E-06 9.23E-06 72 241 "CC2D2A,ALAD,LRRC4C,TMEM108,SLC4A4,MYRF,CALB1,KALRN,CNTFR,AKAP5,ZNF521,CLIP3,TENM4,ATRNL1,BOC,RHOBTB1,SV2A,DLG4,DNM1,TSPAN5,SEMA3D,C8orf37,ABCA8,FABP7,CAP2,FLNC,NSG1,TRAF3IP2,DENND2A,CSDC2,GUCY1A2,TCEAL6,NKD1,KCND2,LAMP2,MAP2,MATN2,MEIS1,CCDC80,MYBPC1,NCAM1,NFIA,NME4,PIK3R1,PCDH18,PRRX1,LAMA1,PTN,PTPN13,RAVER2,MEG3,KCNIP1,ZNF354C,CCDC112,SATB1,SCN2A,DZIP1,PKNOX2,PALLD,ZCCHC24,PEG10,NPAS3,PSD3,ZFPM2,ASXL3,ZNF346,TRPS1,AMOT,FLRT2,PLEKHH2,ZFP37,KCNAB1" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_1000 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.28E-07 6.53E-04 1.01E-06 9.24E-06 195 839 "ABAT,AS3MT,C3orf14,FMNL2,KLHL32,ADRB2,OSBPL8,C1QTNF1,ALCAM,BCAR3,ANXA7,APBB2,EPB41L5,APLP1,UPRT,APP,ARHGAP5,ARNTL,ARRB1,ASPA,DDX3Y,TMEM108,B3GALT2,ATP6V0A1,SEC11C,CFLAR,DST,OSGIN2,CA12,THSD7A,CAMK2D,CD81,MYOM2,LRBA,LRRFIP1,CACNA2D2,CLCN3,CLTB,C4orf33,QKI,COL4A5,ACBD5,CLOCK,ANKRD44,AATK,SNCAIP,PDE4DIP,KIAA0040,DOCK4,MYADM,ARHGAP32,ARHGAP24,AIF1L,SIRPA,ELMO1,MAGI2,TSPAN5,HIPK3,TMTC1,FRY,OPTN,SH3GLB1,EML1,EPHB1,CEP85L,RTN3,TLR7,ACSL4,CORO2B,EFEMP1,ATP8A1,ST3GAL6,TESK2,SGIP1,UFM1,PDLIM5,NPTN,ST6GALNAC3,GABRA4,GABRB1,CAB39,ILDR2,GALC,IQGAP2,ERAP1,SYT17,GGT5,MALT1,NTNG2,RAB30,AIFM3,FERMT2,GPD2,TDRKH,STON1,TPPP,PARD3B,GSN,AP4S1,WIF1,RASSF8,UBE2QL1,ZHX1,NXPH3,GABARAPL2,SYNPO,HNMT,IL6R,IL6ST,ZNF385B,ITGAV,LAMP2,VWA5A,GPR155,MAPT,AFF1,LYRM9,MYO6,NCF2,NEK1,NELL2,NRDC,NTRK3,PCSK5,PDE3A,PDE3B,PDE4B,PDE4D,CCSER2,RETREG1,PLCL1,SCHIP1,SLC36A4,FA2H,MINDY2,PKIA,LRRC49,PTH1R,PTPRD,PTPRO,RIPOR1,PLEKHB2,FAM184A,ZDHHC14,FIGN,RAVER2,KIRREL1,ROBO2,ST6GALNAC6,WLS,GALNT10,HSPA4L,ST6GAL1,CCDC92,ST3GAL3,ABLIM3,SLA,FAM81A,CPEB4,LMBRD1,KDM4C,DDN,ITPRID2,NXT2,KANK1,VPS13A,TMEM150C,ASTN2,ANKRD12,SYNE1,PSD3,ARHGEF12,TNS2,FRYL,AHCYL2,TGFBR3,TJP1,ZFP91,DAAM2,TPD52,NPL,FNDC5,SGK3,FLRT2,PLEKHH2,TOM1L2,ZBTB38,SPIRE1,SYNC,PMEPA1,SEMA3B,AMN1,CERS6,MSRB3,FRMD6" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500_k3 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.30E-07 6.61E-04 1.03E-06 9.34E-06 61 193 "SLITRK1,AXIN2,SORCS1,SEMA6A,FGD2,PDE8B,ZNF599,BMP7,BMPR1B,CACNA1B,CALB1,CRLF1,B4GALT6,TMEM59L,HAPLN1,IPCEF1,PHACTR3,CNTNAP2,CTNND2,EMX2,SPSB4,FGF12,SEMA4D,RASL10A,GFRA1,KIRREL3,MAP7D2,GRIK1,GRIK2,MFSD2A,PADI2,FRMD5,L1CAM,KITLG,VWA2,NRCAM,PFKFB3,SEMA5B,SLC25A23,EML5,RASGRF2,RET,NUDT11,SOX8,SCN2B,SCN4B,SHMT2,FHOD3,RAP1GAP2,LRRC4,SYT11,NUDT10,UNC5D,WSCD1,TCF7,PRMT8,DCBLD1,RPRM,SLAIN1,VSNL1,FSTL5" Coexpression Atlas GSM605839_500 "Myeloid Cells, DC.8-4-11b-.Sp, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Spleen, avg-1" "Immgen.org, GSE15907" 1.31E-07 6.68E-04 1.03E-06 9.43E-06 109 412 "FMNL2,PTCHD1,ALCAM,FAM135A,AMPD3,FGD2,APP,SHTN1,CASK,CADM3,ADAM23,ST3GAL5,CACNA1E,DDR1,CD86,SCARB1,CHN2,B4GALT6,LY86,ZNF385A,CSF1R,CST3,CTNND2,USP6NL,CX3CR1,CYBB,DOCK4,HDAC9,MYADM,SIRPA,SRGAP3,DLG2,CDON,DSCAM,ARRDC4,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FGFR1,FGR,NEK6,GATM,RAB30,GPM6B,ADAP1,ZNF496,GSN,FRMD5,IRF8,LRRC25,DOCK7,IL6R,JAK2,KIT,L1CAM,LIFR,ADAM11,MEF2C,STK32C,MYO5A,MYO9A,CLEC9A,NUCB2,PFKFB3,CDK14,ABCB1,PLTP,RASGEF1B,PTAFR,PTK2,TMEM231,PID1,C1orf54,ROGDI,RGS12,SNX22,PRR5L,ACER3,LRRK2,KCNIP3,RTN1,SCN3A,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,RGL1,SULF2,TMEM150C,ADGRL3,TCF4,KIAA0930,CYB561A3,SLC44A1,DDHD1,TNS1,NPL,TRPM2,TRPS1,SIGLEC10,PLD4,CERS6,NLRP3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.35E-07 6.86E-04 1.06E-06 9.66E-06 51 151 "USP31,ARHGAP20,APC,SLC4A4,CACNA2D1,CALB1,LGI1,CHGB,COL9A1,ZEB2,ELMO1,EBF1,EDNRB,HIPK3,SEMA3D,CALCRL,DLC1,GFRA2,RAB40B,WIF1,RASSF8,IFI16,RBPJ,LSAMP,MATN2,MYH6,NFIA,NTRK2,DDR2,CLDN11,PENK,PIK3C2A,PRRX1,PTX3,TMEM255A,RGS4,LGI2,ELMOD1,ZHX3,CLASP2,EPB41L3,ARHGEF9,TEK,ZFPM2,HHIP,RGMB,TRPS1,TMEFF2,PCDH20,KCNAB1,SOCS4" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500 FaceBase_ST1 1.44E-07 7.36E-04 1.14E-06 1.03E-05 94 342 "TTYH1,ASPHD1,NDRG2,KLHL32,C1QTNF4,PDXK,ASCL1,TTC9B,FGF17,RAB29,USP2,NOG,CHGA,JAM2,LHX2,RAB33A,CLTB,FEZ1,NRSN1,SCRN1,SRGAP3,DLX1,OLIG1,ELAVL3,RGS17,OLIG2,CEND1,FABP7,ZIC4,FOXG1,CGREF1,CSPG5,TPPP3,GAD2,NKX6-2,RUNDC3A,PCSK1N,KCNMB4,PRRC2B,TDRKH,SERP2,GSTT2,MFSD2A,CELF3,UBE2QL1,GABARAPL2,IGFBPL1,TCEAL6,ATCAY,BTBD17,NIM1K,HES5,TUBB2B,LRRTM1,KCNN1,LMO1,FGFBP3,PACRG,MAP6,MT3,SCG3,TAGLN3,LYRM9,NFIA,NRGN,KCNK10,SLC10A4,GDAP1L1,POU3F4,NKAIN4,RGS10,MEG3,LINC00461,HES6,SMPD3,SCG5,SLC4A3,SMARCD3,SOX2,NPAS3,NACAD,APOM,ADAMTS17,SYT5,TAC3,TNNT1,TPD52,CHST5,RFTN2,FAM181B,XRCC4,PMEPA1,SHD,STMN4" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k4_200 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.47E-07 7.48E-04 1.15E-06 1.05E-05 14 20 "CRMP1,TUBB3,DPYSL4,GAP43,STMN2,INSM1,TUBB2B,NEFM,SCG5,SOX2,ZIC1,ZIC3,PCBP4,VANGL2" Coexpression Atlas PCBC_ratio_ECTO UCB CD34+Z_vs_ECTO blastocyst_cfr-2X-p05 ECTO UCB CD34+Z_vs_ECTO blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.54E-07 7.84E-04 1.21E-06 1.10E-05 87 310 "TTYH1,PLEKHG5,PLEKHH1,SORCS2,C1QTNF4,MYRF,LHX2,ARHGEF6,LRIG1,FEZ1,ARHGEF4,HDAC9,KIF26A,ARMCX2,SRGAP3,FAM57B,CACNG7,PLEKHA1,PCOLCE2,NCALD,TMEM74,GPR153,TPPP3,PHYHIPL,SALL3,NEK6,TOX3,GPM6A,CROCCP2,PTPN5,SOX21,FAM107A,CELF3,HPSE2,KNDC1,HES5,ZNF385B,C2CD4C,CDH20,KCNJ4,MAOB,SCAMP5,MN1,MOV10,DDX25,NCAM1,NEFM,NHLH1,NTRK3,PBX1,SEMA5B,CAMKV,POU3F2,NKAIN4,GDPD1,PTCH1,PTPRZ1,RAD52,FEZF2,RLBP1,EMID1,MAPK12,DRAXIN,ARX,SLC6A8,EFHD1,ZNF415,SOX1,SOX2,CAND2,SMOC1,FCHO1,SEPT3,ROBO3,HIF3A,ENHO,NR2E1,TRH,CCDC136,KCNK12,ELFN1,NDRG4,MKRN3,AMZ1,NT5M,RGMA,SIGLEC10" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.55E-07 7.90E-04 1.21E-06 1.11E-05 74 251 "KDM5D,SEMA7A,GAS7,SHTN1,TMEFF1,CADPS,DDX3Y,ATP1A1,ATP1A2,DST,ST3GAL5,SYNJ2,RGN,CDO1,ADGRG1,FADS2,MAGED1,SCRN1,RCAN1,DTNA,DTNB,SIDT2,MRO,SORBS3,EPS8,REEP2,PTK2B,SUCO,SEMA6C,CAMKK2,BRPF3,GATM,PPARGC1A,GPM6B,GPR37,TUBB2B,LRRTM3,KCNH1,KCNK2,SYTL4,NCOA7,MAN2A2,MSI1,NRBP2,CTNNA3,NELL1,PAK3,SLC10A4,SERPINE2,MTRF1L,RASGEF1B,PTCH1,PTPRE,SH3TC2,DUSP15,RNASE1,ROBO1,GLDN,RPS6KA2,MRAS,KIF21A,DOCK10,ST6GAL1,EFHD1,TNIK,SPP1,ADHFE1,TACC1,TIAM1,BEX4,TPD52,SLC38A1,ADAMTS9,NETO2" Coexpression Atlas Arv_SC_fibroblast_500_K1 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 1.55E-07 7.92E-04 1.21E-06 1.11E-05 78 269 "SYN3,TMEM132B,NLGN4X,PDZD4,KIF1A,SYT6,MAP7,CLDN10,CHGA,FAM19A5,IGLON5,COL9A1,GAL3ST1,TCEAL2,RIMS4,RIMS3,FAM57B,USH1C,LINC00599,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,SYT3,B3GAT1,MEGF10,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GRIA4,GRM3,IGSF21,C1orf94,IGFBPL1,SHISA6,CELF5,ATCAY,BTBD17,IGSF1,KCNQ2,FGFBP3,CPNE9,SCG3,DDX25,NNAT,ZDHHC22,GDAP1L1,CAMKV,PPP2R2B,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,RIMKLA,PPM1E,SLC1A6,TMEM132D,SNCB,LHFPL4,ZFR2,ARC,COBL,TAC3,CHST8,ENHO,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.58E-07 8.06E-04 1.23E-06 1.13E-05 53 160 "METAP1D,ADCY8,USP31,AMPH,VAT1L,ATP1A2,BMP7,CACNA2D1,CACNB4,COL9A1,RBM39,CRYM,SNCAIP,RAB39B,DYNC1I1,ELAVL4,TMEM35A,CDHR1,EYA1,ST3GAL6,FGF1,SCARA3,SGIP1,DACH2,MEGF10,GABRB3,GFRA1,GLDC,FAM19A2,FAM107A,HAS2,FRMD3,NEGR1,ITIH2,NELL1,CNTN3,PRTG,FAT3,NXPH1,KANSL1,GAL3ST4,ROBO2,SALL1,MAPK12,ZFP2,HSPA4L,ANKRD6,SLC1A3,SLC12A2,NEK4,ERCC6L2,TPM2,LRP8" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_2500_K3 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.63E-07 8.33E-04 1.27E-06 1.16E-05 88 315 "CPNE2,KLHL32,PLEKHH1,PHF12,APBB1,NUMB,SNAI3-AS1,MPDZ,BCL7A,BMPR1B,ARHGEF7,CFAP410,PRC1,KRIT1,C1orf52,CDC25B,ZNF445,SRSF11,CHN2,LHX2,QKI,NCOR2,SIPA1L1,RIMS2,ST18,USP6NL,RASSF2,CTIF,JAKMIP2,TMCC2,DLX1,AASDH,PLXNC1,RTN3,RRAGB,PRKAG2,ATP6V1H,MSANTD4,FYN,AHCYL1,BRPF3,IQGAP2,GPM6A,GRIK2,FAM222A,TOX2,KIF5C,PAXBP1,MDM4,SETD4,PCMT1,ING3,NKAIN1,GAL3ST4,PBRM1,EXD2,ADAL,RMI1,MAPK12,SARS,ZFP2,SOX6,CASC3,ASRGL1,HSPA4L,KIF21A,FBXO11,FAM81A,SLC12A2,SON,SP4,ZBTB43,STAU1,ZC3H4,SYNE2,ATMIN,CLASP1,ARHGEF12,FRYL,HEY1,BHLHB9,TP53BP1,MEAF6,ZBTB14,PRDM10,RSPRY1,SNX14,GAN" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.76E-07 8.99E-04 1.37E-06 1.25E-05 25 53 "PCDH10,INSYN2B,DCLK1,TOX,SPOCK3,EPHA5,TMEM132C,SCML2,FOXF2,MEGF10,DNER,GLRB,LPAR4,WIF1,IFI16,MYH3,PCDH8,PRRX1,ZFHX4,CSRNP3,TAC1,UNC5D,ADGRL3,TBX15,SOCS4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.77E-07 9.05E-04 1.38E-06 1.26E-05 20 37 "TTYH1,NDRG2,SPARCL1,ATP1A2,NCAN,LYPD1,EDNRB,FABP7,C1orf61,GPM6B,SCRG1,HES5,FGFBP3,NFIA,NTRK2,PMP2,PTN,PTPRZ1,BCAN,SLC1A3" Coexpression Atlas ratio_SC_vs_MESO_1000_K1 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 1.81E-07 9.24E-04 1.41E-06 1.28E-05 49 144 "FAM43B,ATP1A2,ATP1A3,CADM3,AZGP1,LDHD,DIRAS1,CHGB,CABP1,CP,SLC45A1,NCALD,HSPA12B,SORBS1,TMEM151A,ABLIM2,CPLX2,DNER,ALDH1L1,C1QL1,LNX1,CCDC184,FRMD3,INSYN1,NEGR1,MAPT,MT1M,PDE3A,ST8SIA5,FXYD1,SCHIP1,SEPT4,NKAIN4,PTPRO,PYGM,SCN4B,FHOD3,ABCC8,SYT4,CNTN2,TIMP4,RASD2,SYNPO2,LGI4,TRIM9,CRB2,SLC30A3,SLC17A7,KCNAB1" Coexpression Atlas gudmap_developingGonad_e11.5_testes_1000 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.83E-07 9.36E-04 1.42E-06 1.30E-05 195 843 "DGCR6,ABCF1,ACLY,ACTN1,KDM5D,ARID1A,ADD1,KIDINS220,NR0B1,AK2,OGT,EPB41L5,APLP1,DGKZ,CASK,ASCL1,NUMB,DDX3Y,BACH1,MYRF,BTRC,DDR1,CALB1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,INA,ARHGEF1,ARHGEF2,CDC42,ARHGAP33,LHX2,FADS2,COL9A1,ZNF385A,RBM39,CRMP1,HAPLN1,RNF14,CLIP3,CSNK1E,PUM1,KIAA0408,ARHGAP32,TCAF1,DAPK1,DAPK3,DBI,DBN1,DCTN1,BLOC1S6,GSDME,ALKBH8,RCAN1,DNM1L,EDNRA,MBNL2,EIF4G1,ELAVL4,EMX2,PLEKHO1,EPB41L2,KATNAL1,FABP7,TUBB3,PRMT5,SEC24B,FGFR1,MEX3B,SYNCRIP,FOXM1,DPYSL4,ZBED3,DLL3,NEK6,GAP43,GART,AHDC1,DHRS4,TCERG1,TOX3,KIAA1958,OS9,GNG3,GPM6B,LPAR4,GPR37,STMN2,GRB10,BACH2,SMAP1,C5orf24,NKD1,INSM1,TUBB2B,KLC1,SMAD1,MAPT,CHIC1,MEIS2,TAGLN3,NASP,NCAM1,NEFM,NELL2,NEUROD1,NNAT,DDR2,PALM,PDGFRA,GNG2,OLA1,PIK3R1,PKM,SLC25A23,PCDH18,RC3H2,EXOSC10,PPP2R5E,PRKACB,ZIK1,PTPRG,PEX5,GAL3ST4,FIGN,RFX4,UBR7,ZFHX4,MEG3,ATAT1,ATXN2,LINC00461,HES6,SEC14L1,SFPQ,SCG5,ITSN1,ARX,SHMT2,WDR37,SLC1A3,ZKSCAN3,SMARCA4,SNAP25,SNRPN,SON,SOX2,SOX5,ZCCHC24,SOX11,CAND2,RBM26,SPART,TROVE2,SULF2,GSE1,SYT11,JMJD6,PRRC2C,SYNE2,PJA1,FBXW11,KLHL4,TCF4,TRIM2,USP22,CLASP1,PUM2,TMEM9,ASXL3,TNS1,RBFOX2,TRIO,STXBP4,ZMYND8,TSC2,TST,TTC3,UCHL1,PITPNB,USP1,CLDND1,SF1,ZIC1,ZIC3,ZFAND5,INTS3,STOX2,VPS35L,PCBP4,RTN4,VANGL2,ST8SIA2" Coexpression Atlas PCBC_SC_500 Progenitor-Cell-Biology-Consortium_StemCell_top-relative-expression-ranked_500 PCBC 1.92E-07 9.77E-04 1.48E-06 1.35E-05 126 497 "SYN3,TMEM132B,ADCY2,ADD2,UNC5A,NLGN4X,PDZD4,RASL11B,KIF1A,SYT6,MAP7,CLDN10,CHGA,RAB3C,DLGAP3,IGLON5,CABP1,COL9A1,GAL3ST1,TCEAL2,HS3ST5,RIMS4,CNTNAP2,SEC14L5,RIMS3,BRINP1,HS3ST4,CALN1,FAM57B,AASS,LINC00599,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,GRM3,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,CELF5,ATCAY,BTBD17,IGSF1,KCND2,KCNQ2,KIF5C,CAMK2N2,FGFBP3,MATK,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PACSIN1,PPP2R2B,NKAIN4,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,SYNDIG1,RYR1,TMEM200C,SLC1A6,SNCB,SOX3,LHFPL4,SEPT3,ACSBG1,ZFR2,RHBDL3,ARC,COBL,TAC1,TAC3,TMEM151B,CHST8,GALNT17,ENHO,ANKRD24,RPRM,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,CRB2,SLC30A3,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas Arv_SC-LF_500_K3 AravindRamakr_StemCell-LF_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 1.93E-07 9.86E-04 1.49E-06 1.36E-05 94 344 "ADCY2,NLGN4X,PDZD4,RASL11B,KIF1A,SYT6,MAP7,CLDN10,CHGA,RAB3C,IGLON5,COL9A1,GAL3ST1,TCEAL2,HS3ST5,RIMS4,SEC14L5,RIMS3,BRINP1,FAM57B,DPP6,EDNRB,LINC00599,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,SYT3,CSPG5,B3GAT1,MEGF10,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GPM6B,LPAR4,GRIA4,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,SHISA6,CELF5,BTBD17,IGSF1,KCND2,KCNQ2,KIF5C,CAMK2N2,FGFBP3,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,ZDHHC22,PAH,GDAP1L1,CAMKV,POU3F4,PPP2R2B,RAB39A,GDPD2,TMEM145,NKAIN1,SLC1A6,TMEM132D,SNCB,SOX3,LHFPL4,ZFR2,ARC,COBL,TAC1,TAC3,TMEM151B,CHST8,ENHO,ANKRD24,VSNL1,RBFOX3,ZIC3,KCNT2,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000 DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.95E-07 9.93E-04 1.50E-06 1.37E-05 181 772 "TKTL1,ADARB2,SLITRK1,TMCC3,ADD1,ADD3,PNMA8B,ADORA1,MTUS1,NR0B1,TAOK1,LCORL,PKP4,LGR5,PLA2G4C,PDE8B,INSYN2B,BACH1,SEC11C,RGS11,SYNJ1,ST3GAL5,ARHGEF7,SCAPER,JAZF1,SGCE,MMD2,BTRC,CACNB2,USP2,SRSF11,CHM,JAM2,KMT2C,CLU,NMT2,ABI3BP,MYRIP,RBM39,GDA,TENM4,CSNK1E,PHACTR3,PLXNA4,GREB1,PUM1,ZC3H11A,GSDME,SNAP91,G3BP2,SLC12A6,DTNB,DNAJB6,E2F5,EDNRA,ATL1,PLXNC1,EIF4G1,ELAVL2,MRNIP,CALCRL,EMX2,EPB41L2,LRRC17,SRRM1,EZH1,NRN1,SCML2,KAT8,KIAA1109,FOXO3,SMC2,APOPT1,STAU2,B3GAT1,FYN,GABRA4,ILDR2,DNER,GATM,GDF9,AIFM3,MAP7D2,GPM6B,TDRKH,LPAR4,NR3C1,KIF3A,GUCY1A1,MAEL,TOX2,SYNPO,HNMT,SHISA6,JAK1,KCND2,KIT,SYTL4,CHIC1,KITLG,MMP16,BCO1,RSPO2,MYO5A,NEXMIF,NASP,NELL1,NFIX,NOS1,CNOT4,SETD4,PAK3,PDPK1,ABCB1,SERPINI1,NALCN,PIK3R1,JAKMIP1,PLEC,PLP1,MAPK10,GDPD1,STK32A,SUSD4,RDX,TMLHE,PCMTD2,MEG3,TRAPPC13,SATB1,FAM19A1,PRCD,FNIP1,TNFRSF19,IL17RB,SFPQ,ARX,KIF16B,CPEB3,SYBU,WDR37,EPN2,SLC12A2,SLC14A1,CPEB4,SORCS3,RIMS1,MYT1L,ZC3H13,RBM26,SRPK2,CLSTN2,LARP4,PRRC2C,SYNE2,ANKRD12,CAMTA1,ANO4,DMXL2,DOCK9,PCDHB9,TEX15,MTMR14,CBX5,R3HDM1,PARD3,NR2C2,TSC1,SSBP2,UBE3A,UCHL1,TBC1D15,TRIM9,NDRG4,WNK1,ADAMTS9,NAV2,FAM47E,FAM13C,DPF3,GAN" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K4 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 2.17E-07 1.11E-03 1.67E-06 1.52E-05 78 271 "AS3MT,NDRG2,GALNT16,DSCAML1,HHATL,PNMA8B,GRAMD1B,RNF150,MTUS1,CASKIN1,CARNS1,KCNT1,BEGAIN,TRMT9B,MYH7B,GPAM,TNRC6C,CPNE5,KIAA1614,SPTBN4,ZSCAN18,SLC2A11,CADM3,AZGP1,JAM2,CCDC3,TRAPPC9,SLC25A18,SYT15,TMEM132C,CHL1,BACH2,HAPLN2,HP,SLCO1C1,DUSP26,TMEM38A,SLC25A23,ROGDI,CRTAC1,ARHGEF10L,DCUN1D2,MYH14,TMEM100,SYNDIG1,DGLUCY,SMPD3,SOX6,KIF21A,ASAP3,FHOD3,PKNOX2,EFHD1,SPHKAP,GKAP1,ABTB1,TSPYL2,LHPP,CLSTN2,POPDC3,HIF3A,ZNF106,CDH22,GZF1,PDIA2,ETNPPL,PCDH20,NDRG4,SLC26A10,REEP1,SHD,ADAMTS9,SLC17A7,PCBP4,WNK2,HRASLS,ADAMTSL3,ADAMTS10" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 2.28E-07 1.16E-03 1.75E-06 1.60E-05 30 71 "KIAA1324,ATP1A3,MAP7,NECTIN3,PLCH2,EFNA3,ELAVL4,EMX2,ATP8A1,FHL1,FUT9,GRIK4,HPCA,INSM1,KCNN3,KIT,PAX6,PLP1,MASP1,GDPD2,FEZF2,RFX4,SLC1A2,LMO3,C3orf70,PRMT8,RBFOX3,TRIM9,TMEM163,PRRT4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200_k2 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.31E-07 1.18E-03 1.78E-06 1.62E-05 33 82 "SORCS2,C1QTNF3,SYT13,IL33,RUNX1T1,LDB2,CDH2,CDH10,FAM171B,BOC,SRGAP3,NTM,EBF1,SEMA3D,TMTC1,ELAVL2,GLRB,RAB40B,GRIA4,UBE2QL1,KCND2,PDGFRA,PIK3R1,PTPRD,FAT4,CSRNP3,FAM19A1,NTNG1,MAPKBP1,TROVE2,ANO4,TEX15,SSBP2" Coexpression Atlas PCBC_DE_blastocyst_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_1000 PCBC 2.37E-07 1.21E-03 1.82E-06 1.66E-05 223 991 "KCNH8,ACHE,CSMD2,TMEM132B,ADCY2,GALNT13,ADD2,SORCS1,ERMN,PTCHD1,NLGN4X,NR0B1,SEMA6A,ARHGAP20,PCDH10,UNC79,PDZD4,DPP10,GAS7,APOC1,LGR5,SLC7A14,RASL11B,RNF182,KIF1A,CARMIL3,FGF17,CACNA1G,CALB1,MAP7,CLDN10,CCKBR,CDH10,DCLK1,CHGA,DLGAP3,FAM189A2,FAM19A5,IGLON5,COL9A1,GAL3ST1,TCEAL2,HS3ST5,TENM4,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,RIMS3,KCTD8,BRINP1,AIF1L,C8orf34,LYPD1,PLPPR4,HS3ST4,HS3ST2,CALN1,DPP6,FAM78B,ST8SIA3,EFNA2,ZNF391,CDHR1,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,DACH2,B3GAT1,TBR1,MEGF10,GABRA1,HRASLS5,GABRA3,GABRA5,CHL1,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,GNAL,GNG4,GPM6A,GPM6B,LPAR4,GPR37,TMEM121B,CECR2,GRM2,GSTT2,TMEM179,HAS2,IGSF21,C1orf94,BACH2,IGFBPL1,C9orf129,HP,SHISA6,CELF5,ATCAY,NKD1,IGSF1,ZNF678,TUBB2B,C2CD4C,KCND2,KCNF1,CLVS2,KCNJ3,KCNJ5,KCNN1,KCNQ2,GATD1,KIF5C,KIT,CAMK2N2,FGFBP3,C2orf80,MOBP,ZNF680,SCG3,DDX25,TCEAL5,RCOR2,NNAT,NODAL,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,PDZRN4,MAGEL2,PACSIN1,FA2H,FAT3,PPP2R2B,PPP2R2C,RASGEF1B,RAB39A,RELN,LAMA1,ELOVL2,STK32A,NKAIN1,ZNF844,SLC25A48,ACSS3,FAM184A,ZNF493,KHDRBS2,RET,PRIMA1,MAP6D1,CNTNAP3,HUNK,RXRG,TMEM200C,SLC1A6,TMEM132D,INAVA,SOX3,SOX10,SOX15,LHFPL4,BEX1,MCF2L2,NFASC,ZFR2,NUDT10,ADAMTS17,SYT4,UNC5D,KLHL4,PCDHGA11,FAM189A1,ARHGAP9,PCDHA6,CHST8,LEFTY2,GALNT17,ENHO,TMOD1,FAM124A,ANKRD24,CSMD1,PIK3R5,SEZ6L,TRPM2,CA14,ANO5,RPRM,PDIA2,RBFOX3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,ANKS1B,CADM2,SHD,STOX2,XKR7,GAL3ST3,WNK3,PLSCR4,CASC15,NETO1,AP3B2,SLC4A10,FAM198A,JPH3" Coexpression Atlas GSM854326_500 "Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3" "Immgen.org, GSE15907" 2.39E-07 1.22E-03 1.83E-06 1.67E-05 107 407 "CSMD3,TMCC3,ADORA3,ADRB2,BEND6,MTUS1,ABCD2,BIN1,FGD2,APP,CASK,ARHGAP5,ASPH,NUMB,ATP6V0A1,ADAM15,DST,ST3GAL5,C1QC,SGCE,CAPN3,FMNL3,USP2,CD86,CD81,LARGE1,ADGRG1,JAM2,ARHGAP22,LY86,CRYBB1,CSF1R,CSF3R,CST3,CTNND1,CX3CR1,DOCK4,SIRPA,RHOBTB1,RCAN1,PLEKHO1,EPB41L2,ETV1,TLR7,FCGR1A,ST3GAL6,TMEM107,KHDRBS3,GAB1,NEK6,ATP8A2,GATM,HPGDS,GLUL,GPR34,LRRC25,IL6R,ITGAM,KCND1,LIFR,LMO2,GPR155,MEF2C,SCAMP5,P2RY13,NCF2,OPHN1,P2RX7,TREM2,SERPINE2,SMOX,PMP22,RASGEF1B,TMEM104,PTAFR,RAB3IL1,ROGDI,GAL3ST4,RGS10,TMEM206,TMEM100,ACER3,RTN1,SALL1,MRAS,SGK1,SLC1A3,SLC2A5,ARHGEF40,SLC11A1,SLC12A2,SLC37A2,TF,TJP1,TLR4,LRRC8A,NPL,RGMB,P2RY12,AGMO,PMEPA1,HPS4,NAV3,ITM2C,PLD4,MVB12B,NLRP3" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500 DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.41E-07 1.23E-03 1.84E-06 1.68E-05 103 388 "TKTL1,TMCC3,ADD1,PNMA8B,ADORA1,NR0B1,LCORL,PKP4,LGR5,PDE8B,DDX3Y,INSYN2B,BACH1,SYNJ1,ARHGEF7,JAZF1,BTRC,CACNB2,SRSF11,CHM,KMT2C,CLU,CNR1,COL4A5,ABI3BP,RBM39,TENM4,DZIP3,GREB1,PUM1,DOCK4,FGFR1OP2,ZC3H11A,GSDME,G3BP2,DYNC1I1,EDNRA,RASGRP1,PLXNC1,EIF4G1,ELAVL2,CALCRL,EMX2,EPB41L2,NRN1,SCML2,MEX3B,GABRB1,ILDR2,GATM,AIFM3,MAP7D2,LPAR4,KIF3A,MAEL,SHISA6,KCND2,KIT,CHIC1,KITLG,MMP16,RSPO2,NEXMIF,NASP,CNOT4,GLIPR1L2,PDPK1,ABCB1,SERPINI1,PLP1,MAPK10,GDPD1,RNASEL,TMLHE,MEG3,LRRTM4,PRCD,FNIP1,TNFRSF19,SFPQ,ARX,CPEB3,SYBU,SLC12A2,SCMH1,CPEB4,MYT1L,ZC3H13,RBM26,LARP4,SYNE2,ANKRD12,DMXL2,TEX15,CBX5,R3HDM1,RASD2,SSBP2,ZNF711,ZNF23,NDRG4,ADAMTS9,GAN" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K1 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.45E-07 1.25E-03 1.87E-06 1.71E-05 119 465 "ACTN2,METAP1D,ADCY2,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,C1QC,IL33,LDLRAD4,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,ARMCX1,PTK2B,HPCAL4,DLL3,ABLIM2,FYB1,GAA,ARPP21,GHDC,TMEM8B,GHR,LYVE1,GLRB,GNG4,ADAP1,GRK4,GRIA1,TMEM25,GUCY1B1,ICA1,SCIN,IL11RA,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,CPNE9,MYH3,MYL3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,PEX5,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,PRIMA1,MYH14,STK32B,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,ARHGAP26,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,ATP13A2,TNS1,LRRC24,KCNE5,LAMP5,CADM2,LRP8,PCDH15,DNAH10,DPF3,PRRT4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k4 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.64E-07 1.35E-03 2.01E-06 1.83E-05 56 175 "ADD3,PNMA8B,ARHGAP20,PKP4,ATP2B1,DOCK11,BACH1,IL33,VSTM2A,RUNX1T1,ZNF445,SLIT2,COL4A5,AIF1L,ZEB2,ZC3H11A,CDON,EDNRA,EIF4G1,PCDH11X,LPAR4,GRIK1,GRM7,WIF1,RASSF8,HAS2,KCND3,MAP4,CHIC1,MEIS1,MEIS2,SAMD5,PCDH9,NALCN,PIK3R1,PRRX1,FAT3,MAPK8,PTN,TMEM255A,C1orf54,RNASEL,MEG3,TRA2B,CHD9,TET1,TROVE2,PRRC2C,SYNE2,PCDHB9,CBX5,TRPS1,SSBP2,UBE3A,FLRT2,VLDLR" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkI_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.77E-07 1.41E-03 2.11E-06 1.92E-05 25 54 "HFM1,ASCL1,INA,SEPT7,NRXN2,ELAVL4,EN2,FABP7,TAOK3,C1orf61,NSG2,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,L1CAM,NCAM1,RORB,RTN1,SCN2A,SCN3A,MYT1L,CELF4" Coexpression Atlas gudmap_developingGonad_P2_testes_1000_k4 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.99E-07 1.53E-03 2.27E-06 2.07E-05 88 319 "TTYH1,EMILIN3,TMCC3,ADCYAP1R1,ADORA1,MTUS1,NR0B1,SORCS2,C1QTNF3,AMH,SEMA7A,NT5C3B,ARHGDIG,MARK4,ATP1A2,DST,ST3GAL5,MMD2,CAMK2D,VXN,MAP7,CBLN1,ADGRG1,JAM2,CLU,CLTB,CABP1,PNKD,RASGEF1C,ARHGEF4,TOX,SPOCK2,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,RASL12,REEP2,FGF13,CAMKK2,TPPP3,FYN,GATM,GPM6B,GPR37,HSD17B1,IL6ST,ITPKA,JAK1,TTYH2,MEF2C,MOV10,CD200,NRBP2,MT3,MYO7A,PAK3,PDGFRA,SEMA5B,PLEC,FXYD1,ELOVL2,PTPRE,PYGM,TMEM206,MEG3,SOX8,S100B,SH3GL2,BCAN,SLC1A6,EFHD1,SPP1,SULF2,ACSBG1,TBL1X,SIN3B,HHIP,THRA,NR2C2,TST,SGK3,UBTF,FLRT1" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_1000 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000 PCBC 3.02E-07 1.54E-03 2.29E-06 2.09E-05 223 994 "ABHD6,TKTL1,TMCC3,SORCS2,TRMT9B,CCDC146,APLP1,LGR5,LINC00173,DACT3,DNAJC27-AS1,IL33,CA4,CABP7,CAMK2A,VXN,ISPD,SLC16A4,P2RX6,NEURL1,CDH2,CDH18,LGI1,IGFN1,NOG,ADGRG1,LHX2,CNTFR,AKAP6,COL9A2,NRG2,FAM171B,SEC31B,HAPLN1,PLCH2,CMTM5,PLCXD3,ST18,BOC,ARHGAP24,DGKG,ZEB2,LYPD1,CCDC3,KIF19,CD99L2,CDON,EDN1,YAF2,MBNL2,EGR3,EMX2,ATP6V1G2-DDX39B,NCALD,NRN1,CLVS1,TMEM132C,ZIC4,PRAM1,DLC1,ATP13A4,TMEM175,TPPP3,PHYHIPL,ILDR2,DENND2A,IP6K3,GPR162,ADAM28,KIRREL3,AIFM3,DCLK2,DIPK1C,SPACA9,FAM107A,GUCY1A1,GUCY1B1,ATOH8,FAM222A,CELF3,MAEL,UBE2QL1,HAPLN2,ZNF491,C5orf24,KIAA1755,HES5,LIX1,TMEM240,INSM1,ZNF385B,LRRTM1,NME9,ITPKB,KCNA1,OLFM3,CDH20,LRRC4B,SYTL4,CLEC18A,C1orf194,MAP2,MAP6,IL17D,MEIS1,MEIS2,SAMD5,SESN3,CCDC80,BCO1,NRBP2,TAGLN3,CTNNA3,RSPO2,MDGA1,RTL5,ZNF862,NHLH1,NPY,IGSF11,KCNK10,CNTN3,PAX6,PRTG,PDE1C,ENPP2,HMGCLL1,ASPDH,SDK2,POU3F2,VSTM2L,MAPK10,PROX1,RELN,LAMA1,ELOVL2,PTX3,RIPOR1,STRC,TMEM255A,FEZF2,PRRT2,MORC4,RFX4,RLBP1,ZFHX4,KLHDC8A,KIRREL1,CCDC102B,BAALC,EMID1,MELTF-AS1,HSD11B1L,WLS,YJEFN3,FAM182A,TNFRSF19,SMPD3,SLC30A10,PEAR1,SOX6,ARX,CCDC92,SYBU,FAM214B,PKNOX2,EFHD1,GKAP1,DMRTC1,UNC80,SOX3,SOX5,IZUMO4,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SSPO,ADAMTS17,VWA3A,ZEB1,PCDHGB6,AZIN2,PCDHB10,PCDHA6,PCDHA3,DICER1-AS1,HHIP,ASXL3,NR2E1,RIMBP2,DOK6,TRH,LRRC24,PPIL6,FNDC5,RFTN2,TTPA,CLEC2L,TOM1L2,ZIC1,ELFN1,ZFP41,EMX2OS,PLPP4,CRB2,MKRN3,ZBTB16,DPYSL5,GDPD5,STMN4,ADAMTS9,NAV3,DNAH10,DOCK8,FAM182B,CAMK1G,ZNF248,MSRB3,SLC4A10,FAM181A,PRRT4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.05E-07 1.55E-03 2.31E-06 2.11E-05 102 385 "RALGAPA1,EMILIN3,USP31,TAOK1,ALK,OGT,ANK3,APAF1,APC,DGKD,NRP2,BMP7,SCAPER,CACNA2D1,CANX,ZMYM4,CNRIP1,HAPLN1,TENM4,VCAN,PUM1,TM9SF4,ZEB2,ARNT2,PDCD6IP,DYRK1A,EDNRA,EDNRB,HIPK3,EIF4G1,DCTN4,VPS13B,EPHB1,ETV1,DLC1,SEC24B,KIAA1109,CAMSAP1,SMC2,CAMKK2,GABRA3,AHCYL1,IQGAP2,GFRA1,PCDH17,FERMT2,RAPGEF4,GRIA2,KLF12,BACH2,JAK1,KIF2A,LIFR,LIMS1,CHIC1,PPM1L,NASP,NEK1,NFIA,PIK3C2A,PRRX1,MBOAT7,FAT3,MED1,KANSL1,MAPK8,BCAS3,REV3L,SETD5,MEG3,CLIP1,TNFRSF19,PPP1R9A,NAPB,CPEB4,KIF13A,SON,MYCBP2,KIF1B,CLASP2,EPB41L3,MAPK8IP3,RGL1,STX1A,DNMBP,CAMSAP2,ADGRL3,AGTPBP1,TBL1X,MGRN1,PUM2,HHIP,ASXL3,ERCC6L2,RBFOX2,RGMB,TRPS1,ZNF23,WNK1,STOX2,NUP214,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 3.09E-07 1.58E-03 2.34E-06 2.13E-05 53 163 "SLITRK1,PTCHD1,SHTN1,ATP2B2,DIRAS1,CAMK2A,SLIT2,IQCK,COL4A5,DTNA,CLVS1,ZIC4,SPSB4,AFF2,DLL3,NTNG2,RNFT2,TOX2,BACH2,IGFBPL1,CELF5,ATCAY,ZIC5,IGSF1,BRINP3,KCNH2,CPNE9,LINC00672,SLC11A2,NRCAM,PGAM2,MAPK10,RAD51D,GAL3ST4,CCDC112,LRRTM4,ASRGL1,SLC1A2,TMCC1,SOX5,GSE1,FGD4,RHBDL3,ASTN2,SEMA4A,ACSL6,TRIM2,PSD3,FRYL,AHCYL2,TUB,ZIC1,SENP7" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k2_1000 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.09E-07 1.58E-03 2.34E-06 2.13E-05 53 163 "ADCY6,ESYT2,APP,ATP2A2,ATP2B1,SGCE,CACNA2D1,ARHGEF6,HDAC9,MYADM,ARHGAP24,DGKB,ABCC9,EBF1,FRY,EML1,RCAN2,LRRC17,RASGRP2,MRVI1,DLC1,ST3GAL6,IQGAP2,GNAO1,FERMT2,GUCY1A2,GUCY1A1,GUCY1B1,IL6ST,ITGAV,HECTD2,GPR155,MARK1,ADAM22,NCF2,PDE3A,SERPINE2,SERPINI1,PLCL1,SEPT4,PKIA,PYGM,ZDHHC14,ATXN1,FAM81A,SLC8A1,SLC12A2,CPEB4,TNS1,TPM1,TRPC1,PHTF2,MSRB3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.24E-07 1.65E-03 2.45E-06 2.23E-05 84 301 "FMNL2,KLHL13,NR0B1,KCNT1,OGT,CACHD1,LGR5,PPP4R4,NUMB,INSYN2B,ATP2B3,WASF1,CACNA1D,CACNB2,SLC16A4,DCLK1,MAGI1,CHRM4,PLXNA4,CTH,DOCK4,DAPK1,MAGI2,CDON,DRP2,KLHL5,TMEM35A,EMX2,NRN1,NSG1,GABRA4,GABRB1,GALC,SESN1,PCDH11X,IL6ST,KLHL23,MAP2,KITLG,SESN3,MYO9A,NEXMIF,NFIA,NPR2,PDE1A,CDK14,SERPINI1,PPP3CC,GDPD2,CNTLN,PTPRG,FAT4,REV3L,ZFHX4,TMEM206,LGR4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,ST8SIA1,SLC4A3,SCMH1,ATF7IP,KDM3A,UHRF1BP1L,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,ACTR6,DAAM2,KAT6B,TNNT1,FNDC5,DCBLD1,VAV2,LYPD6,NAV2,FRMD6,DPF3" Coexpression Atlas ratio_SC_vs_DE_500_K3 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 3.30E-07 1.68E-03 2.49E-06 2.27E-05 18 32 "CALB2,CCK,SNCAIP,GALNT9,TMEM130,TMEM151A,DNER,NPTX1,PCSK1,NKAIN4,PTPRO,KCNIP1,ELMOD1,LMO3,TAC1,CRB2,LAMP5,KCNAB1" Coexpression Atlas Lungmap Mouse Lung E16.5 Pericyte Lungmap Mouse Lung E16.5 Pericyte Lungmap CCHMC 3.43E-07 1.75E-03 2.58E-06 2.35E-05 106 405 "ABAT,OSBPL1A,ANK1,ANK2,ZSCAN18,DOCK11,ARHGEF7,CAMK2G,METTL6,ENTPD2,CDH2,RCBTB2,NRXN1,ABCG2,FAM19A5,ARHGEF6,FAM149A,CSF1,MICAL2,TCAF1,BRINP1,DBN1,FAM107B,DMD,FARSB,ABCC5,ABCC9,EBF1,HEYL,EGFR,SPEG,RASL12,F8,ARMCX1,AGAP3,HIGD1B,NFU1,CRCP,RAB30,GNAS,GPM6B,GSN,RNF165,MFSD2A,GUCY1A2,GUCY1A1,GUCY1B1,ITGA7,KCNK3,KLC1,TTYH2,POC1B,CCDC80,BLOC1S2,NME4,NRGN,PDE3A,GPR173,SSH1,SEMA5B,PCDH18,PKIA,WBP1L,PTK2,OCIAD1,NKAIN1,ENOX1,DPF2,FIGN,RGS4,ARHGEF10L,LGI2,PRR5L,EMID1,SEMA6D,FAM81A,SMTN,SIRT2,SLC12A2,PDZD2,SPATA7,ZBTB43,RHBDL3,ARHGEF9,MGRN1,ARHGAP9,GALNT17,THRA,HEY2,TPM2,TRO,PPIL6,SSBP2,USP1,SLC13A3,EML6,TUBA1A,TMEM178A,HPS4,RGS7BP,SMIM8,CERS6,FAM219B,ADAMTSL3,FRMD6,SENP7" Coexpression Atlas GSM854299_500 "Plasmacytoid, DC.pDC.8+.SLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-3" "Immgen.org, GSE15907" 3.62E-07 1.84E-03 2.72E-06 2.48E-05 108 415 "CPNE2,ABHD6,FMNL2,SNX30,PDZD4,SEMA7A,FGD2,GAS7,CDC14B,ARHGAP5,ASPH,ATP1A3,SEC11C,ZNF599,CACNA1D,CACNA1E,DDR1,CD38,STOML1,FADS2,LY86,MAGED1,ZNF521,CST3,CTNND2,CYBB,HDAC9,ARHGAP32,ARHGAP24,SCRN1,SIRPA,ZEB2,SRGAP3,RABGAP1L,GNE,TOM1,DUSP9,SNX29,EGFR,PLXNC1,TLR7,EYA1,FGR,PRKAG2,HVCN1,AK8,NPTN,FYN,NEK6,GPR162,GPM6B,GRM8,GSN,SLC2A6,MAP4K5,PADI2,IRF8,KHK,LIFR,LMO2,PIK3AP1,GPR155,MAN2A2,MATN2,ADAM11,LDLRAD3,MEF2C,MYO5A,P2RY13,CLEC9A,NUCB2,PGAM2,PLTP,CDIP1,PACSIN1,PTAFR,TMEM231,ROGDI,ZDHHC14,FOXRED2,SCN3A,IL17RB,SELL,ITSN1,PPM1E,ST8SIA1,CCDC88A,ZCCHC24,TEX2,ITPRID2,RGL1,SYNE2,SLC37A2,TCF4,CYB561A3,ATP13A2,SLC44A1,TNS1,TPD52,C9orf85,VAV2,P2RY12,LAT2,LRP8,EVI5,SIGLEC10,TMEM163,PLD4" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.71E-07 1.89E-03 2.78E-06 2.54E-05 115 449 "ACTN2,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,MARCH4,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,SCAPER,C1QC,IL33,LDLRAD4,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,TIAM2,RABGAP1L,CCDC3,DLG2,DRP2,SNX29,TMTC1,RASA4,SEZ6,RAB9B,EPS8,PTK2B,HPCAL4,STAMBP,DLL3,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,GLRB,GNG4,GRK4,TMEM25,GUCY1B1,KNDC1,SCIN,LIX1,IL11RA,ZNF385B,KCNA6,KLHL23,GPR155,MID1,MOBP,CPNE9,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,PILRA,NXPH1,PRKAR1B,MASP1,STRC,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,PRIMA1,MYH14,STK32B,LRRK2,LRFN5,MRAS,SH3GL2,ASAP3,SLC1A2,SLC6A9,ARHGAP26,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,SLC44A1,TMOD1,LAMP5,CADM2,PCDH15,DNAH10,DPF3,PRRT4" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_200_k4 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.73E-07 1.90E-03 2.79E-06 2.55E-05 31 76 "PNMA8B,PKP4,ATP2B1,BACH1,RUNX1T1,SLIT2,COL4A5,ZEB2,ZC3H11A,EIF4G1,EPB41L2,LPAR4,GRM7,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,NASP,PCDH9,PIK3R1,C1orf54,TMLHE,MEG3,TRA2B,PRRC2C,CBX5,R3HDM1,SSBP2,FLRT2" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_500 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.12E-07 2.10E-03 3.08E-06 2.81E-05 114 445 "KLHL32,OSBPL8,C1QTNF1,EPB41L5,APLP1,UPRT,APP,ARHGAP5,ASPA,DDX3Y,TMEM108,B3GALT2,CFLAR,DST,CA12,THSD7A,MYOM2,LRBA,LRRFIP1,CLTB,CLOCK,SNCAIP,DOCK4,ARHGAP32,ARHGAP24,AIF1L,SIRPA,ELMO1,MAGI2,TSPAN5,TMTC1,OPTN,CEP85L,TLR7,ACSL4,CORO2B,ST3GAL6,TESK2,SGIP1,UFM1,PDLIM5,ST6GALNAC3,GABRA4,GABRB1,ILDR2,GALC,IQGAP2,ERAP1,MALT1,FERMT2,TDRKH,PARD3B,WIF1,RASSF8,UBE2QL1,NXPH3,SYNPO,IL6ST,ZNF385B,ITGAV,MAPT,AFF1,LYRM9,MYO6,NEK1,NELL2,NTRK3,PDE3B,PDE4B,PDE4D,CCSER2,RETREG1,PLCL1,SCHIP1,SLC36A4,FA2H,MINDY2,PKIA,LRRC49,PTH1R,PTPRO,RIPOR1,FAM184A,ZDHHC14,RAVER2,ROBO2,ST6GALNAC6,WLS,GALNT10,ST6GAL1,ST3GAL3,ABLIM3,SLA,FAM81A,CPEB4,LMBRD1,DDN,NXT2,KANK1,VPS13A,TMEM150C,ASTN2,PSD3,ARHGEF12,TNS2,FRYL,TGFBR3,TJP1,DAAM2,SGK3,FLRT2,PLEKHH2,SYNC,CERS6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.21E-07 2.15E-03 3.15E-06 2.87E-05 86 312 "DPF1,NDRG2,AXIN2,AGT,SPARCL1,LTBP4,APAF1,GAS7,CASK,RGS20,RUNX1T1,CD81,CDO1,B4GALT6,SLIT2,MAGED1,CP,AKAP12,VCAN,NCAN,DOCK4,ZEB2,CCDC3,DMD,SHANK1,DPYSL2,ABCC5,EDNRA,EDNRB,PCOLCE2,LRRC17,EPHA5,ETV1,FHL1,DKK3,CPLX2,AHDC1,FREM1,FERMT2,GPM6B,RAPGEF4,GRB10,DIDO1,GSN,GUCY1A1,GYG1,IGF1,KCNK3,TTYH2,CHIC1,MN1,NFIA,PBX1,PDGFRA,ENPP2,SERPINE2,FXYD1,PMP22,SEPT4,POU3F2,NKAIN4,PTCH1,CEP97,ROBO2,LGR4,S100B,TNFRSF19,LIMCH1,LMBRD1,PALLD,CAND2,MYCBP2,C11orf87,CLASP2,SAMSN1,SYT11,FGD4,PDLIM2,TCF7L2,TGFBR3,HHIP,LRRC8A,FNDC5,ZIC1,SPIRE1,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K5 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 4.25E-07 2.17E-03 3.17E-06 2.89E-05 66 221 "ABR,KIAA1211,PCDH19,TXNDC16,MRTFA,OGT,MAGEE2,ASTN1,MPDZ,PROM1,DIRAS1,HAP1,ADGRG1,FADS2,SLC4A8,ACBD5,JAKMIP2,PLEKHM1,HP1BP3,EMX2,CLVS1,ACSL4,FGF12,FGFR3,MAD2L2,CAP2,EVL,ZNF605,B3GAT1,GABBR1,GAD1,CECR2,PCLO,MFSD2A,RNFT2,ATG4C,INSM1,KCNH2,LRRC4B,SHC3,SESN3,NFIA,LRP12,MAGEL2,ELOVL2,PEX2,RAD51D,GTDC1,RAVER2,ROBO2,CCDC25,SGSM1,LRRTM4,CASC3,KIF21A,SNAP25,KIF13A,ERC1,SYNE2,COBL,TCF7L2,ARHGEF12,SIK3,BHLHB9,NHSL1,SENP7" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k2 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.29E-07 2.19E-03 3.20E-06 2.91E-05 39 107 "TAOK1,LCORL,SGCE,CDH2,SRSF11,CHM,PLAA,RBM39,TENM4,FGFR1OP2,TCAF1,EPB41L2,SRRM1,ANKFY1,SMC2,APOPT1,SRCAP,PCDH11X,MID1,MMP16,MSI1,NASP,CNOT4,PDPK1,KANSL1,TMLHE,NCBP3,ATXN2,FNIP1,SLC12A2,SCMH1,ZC3H13,SYNE2,R3HDM1,TRIM9,ADAMTS9,SNX27,GAN,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_1000_k1 DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.40E-07 2.24E-03 3.27E-06 2.98E-05 84 303 "USP31,ADRB2,SHROOM2,ARRB1,C1QC,LDLRAD4,CA8,LDB2,CD86,CD38,CHN2,MS4A7,QKI,LY86,CSF1R,CX3CR1,KIF26A,RASSF2,SIRPA,ELMO1,SACS,FAM107B,CCDC3,ABCC9,EDNRB,SLC43A2,IGSF6,TLR7,SIRPB1,F8,FCGR1A,FYB1,ERAP1,GATM,GGTA1P,LYVE1,GPR12,NCKAP1L,IRF8,IFI16,IGF1,VWA5A,SMAD1,PIK3AP1,MAP4,TM6SF1,MEF2C,MSR1,P2RY13,P2RX7,PDE4B,GNG2,PRKCB,RELN,PTPRB,PTPRE,PTX3,RGS10,ATP8B4,SEMA6D,RASA3,DOCK10,ST8SIA1,SLA,PREX2,BTBD3,SLC11A1,LIMCH1,ARHGAP26,SAMSN1,NEK4,RGL1,KLHL4,DOCK9,ARHGAP9,TEK,TLR4,TNFRSF1B,TTPA,VAV1,WIPF1,RGS7BP,FAM13C,SOCS4" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 4.55E-07 2.32E-03 3.38E-06 3.08E-05 107 412 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,CPNE5,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,C1QC,IL33,LDLRAD4,REPS2,KCNAB3,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,ARMCX1,PTK2B,ZMYND15,NPTN,DLL3,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,TCEAL6,SCIN,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,PEX5,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,MORC4,PRIMA1,STK32B,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,TMEM136,FAM189A1,ATP13A2,LRRC24,KCNE5,LAMP5,CADM2,LRP8,PCDH15,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.83E-07 2.46E-03 3.58E-06 3.26E-05 48 144 "KLHL13,NR0B1,SPARCL1,LRRC4C,LGR5,PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,MAGI2,DRP2,EDNRA,PLXNC1,EMX2,LRRC17,NRN1,FABP7,FLNC,AFF2,GABRA4,GATM,FREM1,GUCY1A1,PLD5,KCND2,KLHL23,MAP2,MATN2,NFIA,PCDH9,PDE1A,PDGFRA,PCDH18,PRRX1,TMEM255A,ROBO2,TMEM206,PALLD,SMOC1,ADGRL3,TEX15,ZFPM2,TNNT1,FNDC5,VSNL1,LYPD6" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_500 DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.92E-07 2.51E-03 3.64E-06 3.32E-05 105 403 "ADD1,PNMA8B,NR0B1,SEMA7A,LCORL,PKP4,LGR5,DDX3Y,ATP2B1,RNF182,BACH1,MMD2,BTRC,RUNX1T1,CBLN1,ZNF445,SRSF11,CHGB,CHM,QKI,COL9A3,RBM39,TENM4,FAM169A,DZIP3,PUM1,FGFR1OP2,AIF1L,DCT,ZEB2,ZC3H11A,GSDME,DTNA,EDNRA,PLXNC1,EIF4G1,ELAVL2,EPB41L2,SRRM1,FAM198B,PTK2B,SCML2,ATP8A1,CHST15,MEX3B,SMC2,FYN,GATM,CSDC2,LPAR4,GPR37,FAM19A2,MAEL,MAP4,CHIC1,MEIS1,MEIS2,KITLG,MID1,MSI1,MTR,NASP,NEFM,PAK3,PCSK5,PLTP,MAPK8,DIRAS2,TMEM255A,TMLHE,ROBO2,MEG3,ATXN2,SFPQ,TRA2B,ARX,SLC12A2,TET1,ZKSCAN3,SMARCA4,SOX2,SP4,ZC3H13,KIF1B,RBM26,RGL1,PRRC2C,SYNE2,KLHL4,OBSL1,LEFTY2,CBX5,ASXL3,R3HDM1,TPM1,NR2C2,SSBP2,UBTF,FLRT2,ZIC3,STOX2,ADAMTS9,NAV2,SNX27,GAN" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500_K5 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 5.08E-07 2.59E-03 3.76E-06 3.42E-05 35 92 "NDRG2,LTBP4,GPRASP2,LHX2,CREB5,FEZ1,TOX,EGFR,EMX2,EPHA5,ADGRV1,FGF11,DPYSL4,PCDH17,PPARGC1A,GLDC,PCDH11X,MAP7D2,GRIK2,NR3C1,KLF12,KCNH2,CCDC80,NCAM2,NELL2,PAX6,PCDH9,PGAM2,NECAB2,NTNG1,SOX11,FAM189A1,ZIC3,FMN2,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.14E-07 2.62E-03 3.80E-06 3.46E-05 72 249 "HECW2,PCDH10,LCORL,ASPH,ADAM23,CDK5R1,CBLN1,DCLK1,CDO1,RAB3C,ZNF521,ANKRD44,NCOR1,ERC2,PYGO1,TOX,PITPNC1,TIAM2,MAGI2,SPOCK3,EDNRA,EGFR,TENM1,EPHA5,SCML2,FOXF2,MEGF10,GABRA4,DNER,GLRB,TOX3,ADGRA3,LPAR4,GRIA2,IFI16,KCNA4,LSAMP,DDR2,PCDH8,PDE4D,ENPP2,NLGN3,LRP12,PRRX1,ING3,EPB41L4B,PTPRE,TMEM255A,GAL3ST4,ZFHX4,C12orf49,ROBO1,SATB1,CSRNP3,TNFRSF19,ZNF365,SON,TROVE2,TTBK2,KLHL7,CAMTA1,UNC5D,ADGRL3,TBX15,TCF4,PCDHB15,UGT8,WIPF1,PCDH20,FAM13C,CBLN2,SOCS4" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_k1_100 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.19E-07 2.65E-03 3.83E-06 3.49E-05 11 14 "TUBB3,GAP43,STMN2,TUBB2B,KLC1,NEFM,GNG2,SNRPN,SOX2,PCBP4,VANGL2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.32E-07 2.71E-03 3.91E-06 3.56E-05 45 132 "RNF157,FAM135A,LDLRAD4,RUNX1T1,CDH2,SLIT2,NCOR1,APPL1,ZEB2,CEP170,ETV1,TMEM132C,UBE2E3,FOXF2,MEGF10,GABRA4,GABRB1,DNER,GLRB,RAB40B,MAP4K5,IFI16,KCNK2,RSPO2,NAP1L2,NAP1L3,PCDH8,GPR85,PCDH18,GRAMD1C,FAT4,RGS4,ZFHX4,ARMH4,DZIP1,WDR37,NPAS3,ELOVL4,PLCB1,MTCL1,ADGRL3,TRPS1,MKRN3,GOPC,SOCS4" Coexpression Atlas PCBC_SC_CD34+_500 Progenitor-Cell-Biology-Consortium_StemCell_CD34+_top-relative-expression-ranked_500 PCBC 5.32E-07 2.71E-03 3.91E-06 3.56E-05 124 496 "SYN3,TMEM132B,ADCY2,GALNT13,ADD2,NLGN4X,SEMA6A,PDZD4,RASL11B,KIF1A,SYT6,BRSK2,MAP7,CLDN10,CHGA,RAB3C,DLGAP3,FAM19A5,IGLON5,CABP1,COL9A1,GAL3ST1,TCEAL2,IGDCC3,HS3ST5,ATRNL1,RIMS4,CNTNAP2,KCTD8,BRINP1,HS3ST4,CALN1,FAM57B,AASS,LINC00599,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,GNG4,GPM6B,CECR2,GRIA4,WIF1,IGSF21,C1orf94,HRH3,IGFBPL1,C9orf129,CELF5,ATCAY,BTBD17,PLD5,IGSF1,KCND2,KCNQ2,KIF5C,CAMK2N2,FGFBP3,MATK,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NNAT,NODAL,NPTX1,ZDHHC22,PAH,GDAP1L1,CAMKV,A2ML1,JAKMIP1,EPB41L4B,PACSIN1,PPP2R2B,RAB39A,LAMA1,GDPD2,NKAIN1,ZMAT4,RYR1,TMEM200C,SLC1A6,TMEM132D,IGSF9B,SOX3,LHFPL4,SEPT3,ACSBG1,ZFR2,ARC,COBL,SYT4,TAC1,TAC3,TMEM151B,FAM189A1,CHST8,GALNT17,ENHO,ANKRD24,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500 dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.86E-07 2.99E-03 4.30E-06 3.92E-05 107 414 "FMNL2,SLITRK1,MTA3,KLHL13,NR0B1,ARHGAP20,OGT,SEMA7A,SHTN1,LGR5,CDC14B,SEMA4G,PPP4R4,PDE8B,INSYN2B,ATP2B3,CACNA1D,CACNB2,SLC16A4,DCLK1,MAGI1,UBE2L6,ADGRG1,CHRM4,NMT2,AKAP5,ZNF521,PLXNA4,DOCK4,DAPK1,MAGI2,SRGAP3,DOCK2,DRP2,RASGRP1,KLHL5,PLXNC1,EMX2,EPB41L1,NRN1,AFF2,NSG1,GABRA4,GABRB1,GATM,PCDH11X,PACSIN2,TCEAL6,IGF1,PLD5,IL6ST,KCND2,KLHL23,SYTL4,MAOB,MAP2,KITLG,CCDC80,MTR,MYO9A,NFIA,NPR2,PDE1A,CDK14,SERPINI1,PCDH18,GDPD1,GDPD2,CNTLN,FAT4,REV3L,TMEM206,LGR4,HUNK,SEMA6D,PRCD,TNFRSF19,STUM,RASA3,CNKSR2,ST8SIA1,SLC4A3,SCMH1,SNCA,KDM3A,UHRF1BP1L,TSPYL2,SMOC1,ST5,ADAMTS17,ADGRL3,RPGRIP1L,TCF12,OBSL1,TEX15,DNAH7,ACTR6,DAAM2,TNNT1,FNDC5,DCBLD1,TST,ZNF23,LYPD6,REEP1,WNK3,FRMD6" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.91E-07 3.01E-03 4.32E-06 3.94E-05 19 36 "ABAT,ASCL1,ST18,DCC,ELAVL4,DLL3,SRRM4,IGFBPL1,INSM1,TAGLN3,NEUROD1,NHLH1,POU3F2,KLHDC8A,HES6,SOX11,TCF12,CRB1,PCBP4" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 5.91E-07 3.01E-03 4.32E-06 3.94E-05 19 36 "ABAT,ASCL1,ST18,DCC,ELAVL4,DLL3,SRRM4,IGFBPL1,INSM1,TAGLN3,NEUROD1,NHLH1,POU3F2,KLHDC8A,HES6,SOX11,TCF12,CRB1,PCBP4" Coexpression Atlas PCBC_DE_500 Progenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_500 PCBC 5.96E-07 3.04E-03 4.35E-06 3.96E-05 124 497 "KCNH8,ADCY2,SORCS1,ERMN,NLGN4X,NR0B1,SEMA6A,PCDH10,UNC79,PDZD4,APOC1,LGR5,SLC7A14,ARSE,RASL11B,KIF1A,FGF17,CALB1,MAP7,CLDN10,CCKBR,LGI1,CHGA,FAM189A2,IGLON5,COL9A1,GAL3ST1,TCEAL2,TENM4,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,RIMS3,BRINP1,HS3ST4,CALN1,TMEM74,PIPOX,ADGRV1,FABP7,C1orf61,B3GAT1,MEGF10,GABRA1,HRASLS5,GABRA5,CHL1,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,TMEM121B,CECR2,TMEM179,HAS2,C1orf94,IGFBPL1,TUBB2B,KCND2,CLVS2,KCNQ2,KIF5C,KIT,MATN3,MOBP,SCG3,DDX25,NODAL,GDAP1L1,SEMA5B,JAKMIP1,PDZRN4,PACSIN1,FAT3,PPP2R2B,PPP2R2C,RAB39A,LAMA1,ELOVL2,SLC25A48,FAM184A,RET,PRIMA1,HUNK,RXRG,TMEM200C,SLC1A6,TMEM132D,SOX3,LHFPL4,MCF2L2,ZFR2,NUDT10,TMEM150C,SYT4,KLHL4,FAM189A1,LEFTY2,GALNT17,ENHO,PIK3R5,SEZ6L,TRPM2,CA14,RPRM,RBFOX3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,ANKS1B,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_100 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 5.96E-07 3.04E-03 4.35E-06 3.96E-05 29 70 "VAT1L,CADPS,SCRN1,ELAVL2,LRRC17,EYA1,FABP7,TUBB3,EFEMP1,GAP43,IGSF5,GNG3,STMN2,TAGLN3,NEFM,PDGFRA,SLC10A4,PENK,FAT3,MAPK10,EML5,RTN1,FAM19A1,SCG5,SCN3B,SST,TMEFF2,UCHL1,STMN4" Coexpression Atlas PCBC_ratio_MESO-30_from-OSKM - NLT_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-reprogram_OSKM - NLT_vs_Mesoderm Day 30-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.15E-07 3.13E-03 4.46E-06 4.07E-05 128 517 "ACTN1,ACTN2,TMCC3,AXIN2,SLC44A5,MTUS1,SRPX,MARCH4,PCDH10,USP28,LGR5,TMEM263,DACT3,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,C1QC,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,ATRNL1,PDE4DIP,NTM,CCDC3,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,RCSD1,SIRPB1,PRKAG2,FHL1,CAP2,PDLIM5,NPTN,CSPG5,DKK3,MYOZ2,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,GYG1,SYNPO,IGF1,NKD1,LIX1,BRINP3,ITGA7,KCNK3,LAMA2,HECTD2,IL17D,SESN3,CCDC80,MYH6,MYH7,MYL3,LAYN,BEX5,NDP,ALDH1L2,NPPA,DDR2,PENK,PGAM2,DUSP26,SERPINE2,SSH1,PMP22,PRRX1,EPDR1,CNNM2,PTCH1,PTHLH,KCTD17,RNASE1,SUGCT,WLS,ATXN1,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,SLN,KIF13A,PALLD,ZCCHC24,TEX2,UNC5B,CLSTN2,INKA2,POPDC3,TAC3,KLHL4,ANO4,PSD3,ZFPM2,LEFTY2,ZMAT3,THBS4,TMOD1,DAAM2,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,PLPP4,MSRB3,SSPN,FRMD6,SRGAP2B" Coexpression Atlas PCBC_ratio_MESO-30_from-plasmid_vs_MESO-30_from-ESC_cfr-2X-p05 Mesoderm Day 30-method_plasmid_vs_Mesoderm Day 30-method_NA-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.15E-07 3.13E-03 4.46E-06 4.07E-05 128 517 "ACTN1,ACTN2,TMCC3,AXIN2,SLC44A5,MTUS1,SRPX,MARCH4,PCDH10,USP28,LGR5,TMEM263,DACT3,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,C1QC,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,ATRNL1,PDE4DIP,NTM,CCDC3,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,RCSD1,SIRPB1,PRKAG2,FHL1,CAP2,PDLIM5,NPTN,CSPG5,DKK3,MYOZ2,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,GYG1,SYNPO,IGF1,NKD1,LIX1,BRINP3,ITGA7,KCNK3,LAMA2,HECTD2,IL17D,SESN3,CCDC80,MYH6,MYH7,MYL3,LAYN,BEX5,NDP,ALDH1L2,NPPA,DDR2,PENK,PGAM2,DUSP26,SERPINE2,SSH1,PMP22,PRRX1,EPDR1,CNNM2,PTCH1,PTHLH,KCTD17,RNASE1,SUGCT,WLS,ATXN1,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,SLN,KIF13A,PALLD,ZCCHC24,TEX2,UNC5B,CLSTN2,INKA2,POPDC3,TAC3,KLHL4,ANO4,PSD3,ZFPM2,LEFTY2,ZMAT3,THBS4,TMOD1,DAAM2,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,PLPP4,MSRB3,SSPN,FRMD6,SRGAP2B" Coexpression Atlas PCBC_ratio_MESO-30 fibroblast_vs_MESO-30 blastocyst_cfr-2X-p05 MESO-30 fibroblast_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 6.15E-07 3.13E-03 4.46E-06 4.07E-05 128 517 "ACTN1,ACTN2,TMCC3,AXIN2,SLC44A5,MTUS1,SRPX,MARCH4,PCDH10,USP28,LGR5,TMEM263,DACT3,RASL11B,ATP2A2,MYOM1,RGS9,BMP7,C1QC,CACNA2D1,CAPN3,DGKI,RAB33A,HAPLN1,NCOR2,ATRNL1,PDE4DIP,NTM,CCDC3,DYNC1I1,EDIL3,EDNRA,HEYL,FRY,LRRC17,RCSD1,SIRPB1,PRKAG2,FHL1,CAP2,PDLIM5,NPTN,CSPG5,DKK3,MYOZ2,CSDC2,COPS8,GLI2,KCNMB4,GP1BB,BVES,GUCY1A1,GYG1,SYNPO,IGF1,NKD1,LIX1,BRINP3,ITGA7,KCNK3,LAMA2,HECTD2,IL17D,SESN3,CCDC80,MYH6,MYH7,MYL3,LAYN,BEX5,NDP,ALDH1L2,NPPA,DDR2,PENK,PGAM2,DUSP26,SERPINE2,SSH1,PMP22,PRRX1,EPDR1,CNNM2,PTCH1,PTHLH,KCTD17,RNASE1,SUGCT,WLS,ATXN1,MRAS,SH3BGR,SH3GL3,FHOD3,LIMS2,SLC8A1,SLN,KIF13A,PALLD,ZCCHC24,TEX2,UNC5B,CLSTN2,INKA2,POPDC3,TAC3,KLHL4,ANO4,PSD3,ZFPM2,LEFTY2,ZMAT3,THBS4,TMOD1,DAAM2,TNS1,TPM1,TPM2,SYNPO2,UCHL1,TOM1L2,VSNL1,XRCC4,PLPP4,MSRB3,SSPN,FRMD6,SRGAP2B" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.43E-07 3.28E-03 4.67E-06 4.25E-05 55 175 "SORCS1,PCDH10,LCORL,INSYN2B,DST,RUNX1T1,MYOM2,DCLK1,CDO1,NCOR1,TOX,SPOCK3,DLX1,EPHA5,EYA1,TMEM132C,SCML2,FOXF2,SGIP1,DACH2,MEGF10,GABRA4,GABRB1,DNER,GLRB,LPAR4,GRIA2,WIF1,IFI16,KCNA4,RSPO2,MYH3,NAP1L2,PCDH8,GPR85,TRHDE,PRRX1,TMEM255A,ZFHX4,ROBO1,PRR5L,CSRNP3,SCN3A,LRRTM4,SLC14A1,SOX2,NPAS3,TAC1,UNC5D,ADGRL3,TBX15,PCDHB3,SYNPO2,CBLN2,SOCS4" Coexpression Atlas ratio_SC_vs_ECTO_1000_K1 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#1 PCBC 6.93E-07 3.54E-03 5.02E-06 4.58E-05 130 528 "GPRIN1,ADCY2,ADCY8,ADCYAP1R1,PTCHD1,NLGN4X,PDZD4,CARMIL3,CALB1,SYT6,CBS,DCLK1,CHGA,CHRNA4,RAB3C,FAM189A2,FAM19A5,CRYBB1,GALNT9,VCAN,RIMS4,KIF26A,KCTD8,BRINP1,MAGI2,NTM,RABGAP1L,HS3ST2,CALN1,ST8SIA3,CACNG7,AASS,LINC00599,SEZ6,ANKRD13B,PIPOX,PPP1R1B,OLFM1,HPCAL4,FLT1,CSPG5,MEGF11,MEGF10,GABRA1,HRASLS5,GABRA5,GABRB3,JPH4,ATP8A2,GCK,GNG4,GPM6B,GRIN1,ADAMTS8,LINGO1,WIF1,C1orf94,HRH3,HNF4G,LRRC75A,IGSF1,RIPPLY2,LRRTM3,KCND2,KCNN1,KCNN2,KCNQ2,KHK,KIF5A,CAMK2N2,FGFBP3,C2orf80,CPNE9,SCG3,MYCN,FXYD7,NOS1,NPTX2,HCN1,ZDHHC22,PAH,GDAP1L1,CAMKV,JAKMIP1,EPB41L4B,FAT3,POU3F4,PPP2R2B,PPP2R2C,PRODH,PTPRZ1,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,RIT2,RORB,MRAP2,RIMKLA,RYR1,BCAN,PREX2,SEPHS1,SHANK2,TMEM132D,OGDHL,SNCB,SNRPN,LHFPL4,HECW1,UNC5B,SEPT3,AJAP1,NECAB1,RHBDL3,SYN1,ARC,TAC3,TACR1,KLHL4,TMEM151B,TEX15,CHST8,ENHO,TLL2,IL34,UGT8,ZIC3,NETO1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.97E-07 3.55E-03 5.04E-06 4.59E-05 173 745 "ABAT,EMILIN3,ARID1A,RTL9,SEMA6A,SRPX,MARCH4,ANK1,KCNAB2,CDK10,IGDCC4,SPTBN4,RASL11B,SCAPER,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDH18,CDO1,CRLF1,UBE2L6,CLTB,NIPBL,COL9A2,COL9A3,ABI3BP,IGDCC3,ANKRD44,CLIP3,SNCAIP,SUSD5,ATRNL1,PHF14,BOC,DGKG,RHOBTB1,CCDC3,GRIN3A,DNM1,DNM1L,ABCC9,ELN,HSD17B14,EPB41L1,LRRC17,RAB9B,DENND4A,HSPA12B,WAC,FCGRT,FDFT1,TESK2,SCARA3,HPCAL4,FOXF2,SGIP1,SYT3,NBEA,TRIM16,NSG1,STAU2,TVP23A,ZMAT1,DKK3,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,ZNF638,GRIK4,GSN,WIF1,HPSE2,SYNPO,SMAP1,ICA1,LRRCC1,LIX1,IL11RA,JAK2,CREG2,LAMA2,LAMP2,VWA5A,HECTD2,SMAD9,MAN2A2,SRSF12,MSR1,N6AMT1,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PIRT,PFKFB2,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,CNTLN,ACSS3,IQSEC3,FAT4,RAP1GAP,BEND5,REV3L,ZFHX4,MRAP2,BAALC,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,PREX2,SLC8A1,CCDC88A,SMARCC2,LIMCH1,DOP1A,TNIK,SPATA7,BDP1,ARHGAP26,CDK19,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ASXL3,LRRC8A,ANKRD24,PIK3R5,SYNPO2,STXBP4,TRPS1,RFTN2,PLEKHH2,TSPAN11,WIPF1,ZNF32,PMEPA1,NAV3,CAB39L,CERS6,SSPN,KLHDC1" Coexpression Atlas ratio_ECTO_vs_SC_500_K1 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 7.08E-07 3.61E-03 5.12E-06 4.66E-05 79 283 "ABHD6,LGR5,LINC00173,CA4,CDH18,LGI1,NOG,LHX2,CNTFR,COL9A2,NRG2,SEC31B,HAPLN1,ST18,BOC,LYPD1,EMX2,NCALD,CLVS1,ZIC4,TPPP3,PHYHIPL,ILDR2,GPR162,CELF3,ZNF491,HES5,LIX1,INSM1,ZNF385B,KCNA1,OLFM3,CLEC18A,MAP2,MAP6,MEIS2,BCO1,TAGLN3,MDGA1,RTL5,NHLH1,NPY,KCNK10,PAX6,PRTG,ENPP2,HMGCLL1,ASPDH,SDK2,POU3F2,FEZF2,RFX4,RLBP1,ZFHX4,KLHDC8A,MELTF-AS1,WLS,FAM182A,SLC30A10,ARX,DMRTC1,SOX5,CLSTN2,COLGALT2,STOX1,SMOC1,SSPO,VWA3A,NR2E1,RIMBP2,TRH,ZIC1,EMX2OS,CRB2,MKRN3,DPYSL5,STMN4,ADAMTS9,FAM182B" Coexpression Atlas ovary ovary Human Protein Atlas 7.13E-07 3.64E-03 5.14E-06 4.68E-05 43 125 "KCNT1,RASL11B,CBS,USP6,SNCAIP,TENM4,PLCXD3,GREB1,PABPC5,LRRC17,KCNMB2,ENPP6,CSDC2,GLI2,PCDH11X,GNG4,B4GALNT4,LPAR4,GSTM5,NXPH2,SYTL4,NDP,GPR88,EML5,TMEM255A,KLHDC8A,SCN7A,ARX,SLC4A3,CLSTN2,AJAP1,ANO4,VWC2,VWCE,ZFPM2,ASXL3,FLRT2,VLDLR,KCNT2,LAMP5,NAV3,CAMK1G,DPF3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.13E-07 3.64E-03 5.14E-06 4.68E-05 43 125 "PNMA8B,CDC14B,CACNB2,AP4M1,REPS2,ATRNL1,BOC,SRGAP3,CDON,TSPAN5,NRN1,AFF2,GABRA4,TRAF3IP2,RAB30,PCDH11X,KLHL23,MATN2,MEIS1,CCDC80,NEXMIF,NFIA,NNAT,PDE1A,PCDH18,MAPK9,TUG1,REV3L,RNASEL,LGR4,MEG3,SCN2A,PEG10,SMOC1,ST5,SYNE2,ADAMTS17,ADGRL3,OBSL1,ZFPM2,TRPS1,PLEKHH2,DPF3" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k2 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.96E-07 4.06E-03 5.73E-06 5.22E-05 47 142 "KLHL13,SPARCL1,IGDCC4,CADPS,ADGRB2,FOXN3,AKAP12,PLCXD3,ELAVL2,CALCRL,EPHA5,CAP2,DACH2,GFRA2,LYVE1,GPM6B,LPAR4,NEGR1,IGF1,NKD1,RBPJ,KCND2,MATN2,MMP16,NRBP2,NFIX,CLDN11,PRRX1,PTCH1,TMEM255A,LGI2,ZNF354C,SATB1,TROVE2,EPB41L3,SYT1,EHBP1,VWC2,PUM2,HIF3A,ZFPM2,HHIP,TNNT1,TPM1,SSBP2,TUBB2A,ZNF248" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_200 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.50E-07 4.34E-03 6.11E-06 5.57E-05 29 71 "ADORA1,AMH,SEMA7A,ARHGDIG,JAM2,CLU,TOX,JAKMIP2,ELMO1,PLPPR4,DTNA,MRO,EPS8,ERBB4,TUBB3,FGF13,SEMA6C,GPM6B,MYO7A,PAK3,PGAM2,SERPINE2,RASGEF1B,DUSP15,SH3GL2,EFHD1,TACC1,THRA,SGK3" Coexpression Atlas GSM399442_500 "Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2" "Immgen.org, GSE15907" 8.65E-07 4.41E-03 6.20E-06 5.65E-05 108 422 "CPNE2,ACHE,FMNL2,ADCY6,ZNF608,OSBPL1A,CC2D2A,AMPD2,CDC42BPA,ASPH,MYOM1,DST,CACNB2,MAP7,PRC1,ADGRG1,NRXN1,FADS2,ABCG2,MAGED1,ZNF521,GDA,CSF3R,CTNND1,CYBB,GPRASP1,ARHGAP32,DGKG,DNAJC6,SRGAP3,PLXNC1,MTSS1L,EYA1,MED12L,NBEA,NCKAP1,IQGAP2,GATM,GCNT2,TUBA8,ADGRA3,GRB10,PARD3B,PRDM5,GUCY1A1,IRAK3,HLF,HP,HTR2A,ICA1,DOCK7,USP54,IL12A,ITGAM,KIT,STXBP5,STMN1,LMO2,MEF2C,MEIS1,MDGA1,SAMD14,MYCN,P2RY13,RCOR2,NFIX,NPR2,NRGN,OCRL,P2RY1,PBX1,SERPINE2,ANLN,PILRA,PRODH,LRRC49,DEF8,CNTLN,RIPOR1,SLC6A15,ZNF532,TCP11L1,PEAR1,ITSN1,PPP1R9A,ARHGEF40,SLC14A1,TET1,GSE1,FGD4,ANKRD28,ROBO3,DMXL2,PSD3,ARHGEF12,TEK,TGFBR3,TIE1,CBX5,BHLHB9,TNS1,NPL,STXBP4,SSBP2,VIPR2,ZBTB38,MVB12B,PLSCR4" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 8.65E-07 4.41E-03 6.20E-06 5.65E-05 108 422 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,OSBPL6,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,C1QC,LDLRAD4,CAMK2A,REPS2,KCNAB3,CCPG1,CLU,VAX2,CRYBB1,CSF1R,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,ARMCX1,PTK2B,DLL3,ABLIM2,FYB1,GAA,ARPP21,GHDC,TMEM8B,GHR,LYVE1,GNG4,ADAP1,GRK4,GRIA1,TMEM25,GUCY1B1,TCEAL6,SCIN,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,DEF8,PEX5,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,PRIMA1,LRFN5,MRAS,SH3GL2,ASAP3,SLC1A2,SLC6A9,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,ATP13A2,LRRC24,KCNE5,EML6,LAMP5,CADM2,LRP8,PCDH15,DNAH10,DPF3,PRRT4" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 8.70E-07 4.44E-03 6.22E-06 5.67E-05 14 22 "CADPS,INA,ZNF804A,DLG2,ELAVL2,ELAVL4,FABP7,GABRB3,SCG3,NEFM,EML5,PTPRZ1,CUX2,FSTL5" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.87E-07 4.52E-03 6.33E-06 5.77E-05 44 130 "ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,RUNX1T1,CBLN1,MICAL2,VCAN,RIPOR2,ARMCX2,ZEB2,EDNRA,HEYL,EGFR,LRRC17,EYA1,DLC1,SEPT9,GFRA2,FREM1,GHR,GLI2,GRIA4,GUCY1A1,KLF12,HPSE2,PCDH9,PDGFRA,PLTP,FAT3,SH3KBP1,LRRN3,LAMA1,PTCH1,ROBO2,ARMH4,ACER3,SORCS3,SULF2,TGFBR3,HHIP,STOX2,ST8SIA2" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500_K0 facebase_RNAseq_e8.5_FloorPlate_2500_K0 Gudmap RNAseq 9.41E-07 4.80E-03 6.71E-06 6.12E-05 27 64 "TTYH1,CAMK2A,IQCK,IGDCC3,ELAVL2,ERBB4,ADGRV1,TUBB4A,AFF2,HIGD1B,CECR2,GRIK2,RNF165,CELF3,TOX2,FRMD5,SHISAL1,MAP2,MAP6,NEFM,MAPK4,ELOVL2,HSPA4L,SCG5,WSCD1,ZBTB16,DPYSL5" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k4 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.51E-07 4.85E-03 6.76E-06 6.16E-05 52 164 "METAP1D,ADCY8,NR0B1,AMPH,SFMBT2,SEMA4G,ATP1A2,CDK5R1,CACNB4,FAM19A5,RBM39,CRYM,SNCAIP,SIPA1L1,VCAN,DYNC1I1,DTNA,ELAVL4,TMEM35A,KCNMB2,SPEG,EYA1,FGF1,SCARA3,SGIP1,GABRB3,FUT10,CECR2,FAM107A,FRMD3,ITIH2,MYBPC1,FXYD6,NELL1,CNTN3,RC3H2,FAT3,NXPH1,PPP1R1A,PTHLH,ROBO2,RIMKLA,SUPT20H,HSPA4L,ANKRD6,SLC1A3,SLC12A2,TCF4,TRIM2,RALYL,TPM2,RICTOR" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.51E-07 4.85E-03 6.76E-06 6.16E-05 52 164 "ADCY2,OSBPL6,PCDH10,CADPS,CACNA2D1,CALB1,NRXN3,LY86,CNTN1,CNRIP1,CRYM,VCAN,ZEB2,EPB41L2,NCALD,MRVI1,DACH2,DKK3,GABRA1,GALC,GRM7,GUCY1A1,NEGR1,KCND3,MMP16,CCDC80,NCAM1,NFIA,CLDN11,PCDH8,PENK,PIK3C2A,PRRX1,KANSL1,NKAIN4,PTPRO,PTX3,REV3L,LRFN5,SCN7A,CXXC4,STX1A,CAMSAP2,PDLIM2,ANO4,VWC2,ERCC6L2,SYNPO2,SSBP2,TMEFF2,PROCA1,NAV3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk_Subtype_UnkA_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 9.52E-07 4.86E-03 6.76E-06 6.16E-05 23 50 "ASCL1,INA,SEPT7,NRXN2,ELAVL4,EN2,FABP7,TAOK3,C1orf61,NSG2,GAP43,GPM6A,STMN2,GRIA2,GRIA4,GRIK2,MEST,NCAM1,RTN1,SCN2A,SCN3A,MYT1L,CELF4" Coexpression Atlas PCBC_SC_fibroblast_500 Progenitor-Cell-Biology-Consortium_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 1.03E-06 5.27E-03 7.34E-06 6.69E-05 123 497 "SYN3,TMEM132B,ADCY2,ADD2,NLGN4X,PDZD4,RASL11B,KIF1A,SYT6,MAP7,CLDN10,CHGA,RAB3C,DLGAP3,IGLON5,CABP1,COL9A1,GAL3ST1,TCEAL2,HS3ST5,ATRNL1,RIMS4,CNTNAP2,RIMS3,KCTD8,BRINP1,CALN1,FAM57B,AASS,LINC00599,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,GRM3,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,C9orf129,SHISA6,CELF5,ATCAY,BTBD17,IGSF1,KCND2,KCNQ2,KIF5C,CAMK2N2,FGFBP3,MATK,CPNE9,SCG3,DDX25,FXYD7,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,EPB41L4B,PACSIN1,PPP2R2B,NKAIN4,RAB39A,LAMA1,GDPD2,TMEM145,NKAIN1,RYR1,TMEM200C,SLC1A6,SOX3,LHFPL4,SOX21-AS1,SEPT3,ACSBG1,ZFR2,ARC,COBL,TAC1,TAC3,UNC5D,TMEM151B,CHST8,GALNT17,ENHO,ANKRD24,CA14,RPRM,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,SLC30A3,CADM2,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k4_200 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.04E-06 5.30E-03 7.36E-06 6.71E-05 15 25 "COL9A1,CRMP1,ST18,ELAVL4,GAP43,INSM1,NEFM,PCDH8,RGS4,ZFHX4,SNAP25,SOX2,RBM26,ZIC1,ZIC3" Coexpression Atlas Arv_SC_fibroblast_1000 AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 1.06E-06 5.40E-03 7.48E-06 6.81E-05 219 989 "SYN3,CSMD2,TMEM132B,ADCY2,GALNT13,ADD2,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,PLA2G4C,RASL11B,KIF1A,ADGRB1,LDHD,BTK,C1QC,HAP1,SYT6,BRSK2,MAP7,CLDN10,CCK,SYNGR3,ENTPD2,CHGA,RAB3C,DLGAP3,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,TOGARAM2,IGDCC3,HS3ST5,GDA,LRRC3B,ATRNL1,RIMS4,CNTNAP2,SEC14L5,RIPOR2,RIMS3,KCTD8,BRINP1,HS3ST4,CALN1,FAM57B,DPP6,FAM78B,USH1C,EDNRB,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,IGSF5,GFRA2,GLDC,PCDH11X,GNG3,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,GRIN1,GRM3,LINGO1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,IRF8,BTBD17,C2orf72,ZIC5,IGSF1,RIPPLY2,TUBB2B,ZNF385B,KCND2,KCNN1,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,MATK,CHST6,CPNE9,SCG3,DDX25,MTTP,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,HMGCLL1,SDK2,NECAB2,MAGEL2,EPB41L4B,PACSIN1,PPP2R2B,NKAIN4,RAB39A,SMIM10L2B,LAMA1,GDPD2,STK32A,PTPRZ1,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,HUNK,RYR1,SALL1,SCN4B,TMEM200C,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC6A11,SLC8A2,TMEM132D,SLCO1A2,IGSF9B,SNCB,SOX3,SOX15,LHFPL4,SOX21-AS1,SEPT3,ACSBG1,ABCC8,ZFR2,ARC,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,PIK3R5,RASD2,CA14,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,DPYSL5,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas Arv_SC-HD_1000 AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000 PCBC 1.06E-06 5.40E-03 7.48E-06 6.81E-05 219 989 "SYN3,CSMD2,TMEM132B,ADCY2,GALNT13,ADD2,UNC5A,PTCHD1,NLGN4X,SEMA6A,SYT13,PDZD4,DOC2A,PLA2G4C,RASL11B,KIF1A,ADGRB1,LDHD,BTK,C1QC,HAP1,SYT6,BRSK2,MAP7,CLDN10,CCK,SYNGR3,ENTPD2,CHGA,RAB3C,DLGAP3,FAM19A5,CCDC151,IGLON5,PCYT1B,CABP1,COL9A1,AKAP5,GAL3ST1,TCEAL2,TOGARAM2,IGDCC3,HS3ST5,GDA,LRRC3B,ATRNL1,RIMS4,CNTNAP2,SEC14L5,RIPOR2,RIMS3,KCTD8,BRINP1,HS3ST4,CALN1,FAM57B,DPP6,FAM78B,USH1C,EDNRB,AASS,LINC00599,ELAVL2,SEZ6,TMEM74,PIPOX,ADGRV1,FABP7,PPP1R1B,OLFM1,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,HRASLS5,GABRA3,GABRA5,GABRB3,JPH4,GALR1,SALL3,ATP8A2,IGSF5,GFRA2,GLDC,PCDH11X,GNG3,GNG4,GPM6A,GPM6B,LPAR4,CECR2,GRIA4,GRIN1,GRM3,LINGO1,TMEM179,WIF1,IGSF21,C1orf94,NXPH2,HRH3,HNF4G,IGFBPL1,C9orf129,LRRC75A,SHISA6,CELF5,ATCAY,IRF8,BTBD17,C2orf72,ZIC5,IGSF1,RIPPLY2,TUBB2B,ZNF385B,KCND2,KCNN1,KCNQ2,KIF5A,KIF5C,CAMK2N2,FGFBP3,MATK,CHST6,CPNE9,SCG3,DDX25,MTTP,TCEAL5,FXYD7,NELL2,NNAT,NPTX1,ZDHHC22,PAH,GDAP1L1,SEMA5B,CAMKV,A2ML1,JAKMIP1,HMGCLL1,SDK2,NECAB2,MAGEL2,EPB41L4B,PACSIN1,PPP2R2B,NKAIN4,RAB39A,SMIM10L2B,LAMA1,GDPD2,STK32A,PTPRZ1,TMEM145,NKAIN1,KHDRBS2,ZMAT4,RET,RGS7,RIMKLA,HUNK,RYR1,SALL1,SCN4B,TMEM200C,SH3GL2,PPM1E,SLITRK3,SLC1A6,SLC6A11,SLC8A2,TMEM132D,SLCO1A2,IGSF9B,SNCB,SOX3,SOX15,LHFPL4,SOX21-AS1,SEPT3,ACSBG1,ABCC8,ZFR2,ARC,COBL,TAC1,TAC3,UNC5D,KLHL4,TMEM151B,FAM189A1,CHST8,GALNT17,ENHO,TLL2,FAM124A,ANKRD24,PIK3R5,RASD2,CA14,VIPR2,VSNL1,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,CRB2,DPYSL5,SLC30A3,CADM2,GAL3ST3,AP3B2,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K1 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 1.06E-06 5.41E-03 7.49E-06 6.82E-05 100 385 "ACTN2,METAP1D,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,C1QC,LDLRAD4,REPS2,KCNAB3,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,PLCH2,VCAN,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,PTK2B,SEMA4D,DLL3,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,GLRB,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,TCEAL6,SCIN,ZNF385B,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,PRIMA1,STK32B,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,DOK5,IQSEC2,C11orf87,ACSBG1,ZFR2,TMEM136,FAM189A1,HHIP,LRRC24,KCNE5,LAMP5,CADM2,LRP8,PCDH15,DPF3,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.09E-06 5.57E-03 7.70E-06 7.01E-05 56 182 "NDRG2,ADCY2,ADCYAP1R1,ALCAM,ARHGAP20,LTBP4,GPAM,ADAM23,CACNA1G,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SLIT2,CNTFR,MICAL2,VCAN,RIPOR2,ARHGAP24,ARMCX2,ZEB2,EDNRA,HEYL,FABP7,DLC1,FLNC,GFRA2,FREM1,GHR,GLI2,GRIA4,GUCY1A1,GUCY1B1,KCND3,LAMA2,NCAM1,PCDH9,PDGFRA,FXYD1,PLTP,FAT3,LRRN3,LAMA1,PTCH1,PTN,ROBO2,ARMH4,ACER3,PKNOX2,SULF2,TGFBR3,HHIP,TMEFF2,STOX2,ST8SIA2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.11E-06 5.67E-03 7.81E-06 7.12E-05 85 314 "NDRG2,AXIN2,AGT,CC2D2A,SPARCL1,LTBP4,FAM135A,APAF1,GAS7,ARHGAP5,MTMR2,CACNB2,PTBP2,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,SNCAIP,VCAN,DOCK4,ZEB2,CCDC3,DPYSL2,EDNRA,EDNRB,CERCAM,PCOLCE2,PAN3,LRRC17,ETV1,FECH,FHL1,FOXF2,ZMAT1,DKK3,DENND2A,GFRA2,FREM1,SPIN1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,GPR45,IGF1,KCNK3,TTYH2,LAMA2,MAN2A2,NFIA,ZNF827,PBX1,PDGFRA,ENPP2,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PRKACB,PTCH1,PID1,ROBO2,LGR4,TNFRSF19,SFPQ,SMTN,LIMCH1,PALLD,PDZRN3,RBM26,CLASP2,PDLIM2,AP4E1,TGFBR3,HHIP,PLEKHH2,SPIRE1,PMEPA1,ADAMTS10" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500_k4 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.13E-06 5.75E-03 7.92E-06 7.22E-05 49 152 "PNMA8B,PKP4,ATP2B1,BACH1,SGCE,IL33,RUNX1T1,ZNF445,SRSF11,SLIT2,COL4A5,AIF1L,ZEB2,ZC3H11A,CDON,EIF4G1,EPB41L2,ANKFY1,SMC2,LPAR4,GRM7,RASSF8,HAS2,KCND3,MAP4,CHIC1,MEIS1,MEIS2,SAMD5,PCDH9,PIK3R1,PRRX1,FAT3,MAPK8,TMEM255A,C1orf54,RNASEL,MEG3,TRA2B,CHD9,TET1,PRRC2C,SYNE2,CBX5,TRPS1,SSBP2,UBE3A,FLRT2,VLDLR" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_250 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_250 FaceBase_ST1 1.17E-06 5.96E-03 8.20E-06 7.48E-05 52 165 "TTYH1,KLHL32,C1QTNF4,PDXK,ASCL1,TTC9B,FGF17,NOG,CHGA,JAM2,LHX2,FEZ1,SCRN1,DLX1,OLIG1,ELAVL3,RGS17,OLIG2,CEND1,FABP7,ZIC4,FOXG1,TPPP3,GAD2,RUNDC3A,PCSK1N,PRRC2B,SERP2,UBE2QL1,IGFBPL1,NIM1K,HES5,LMO1,MT3,TAGLN3,LYRM9,NFIA,SLC10A4,GDAP1L1,NKAIN4,LINC00461,SCG5,SLC4A3,SOX2,NPAS3,NACAD,APOM,ADAMTS17,TAC3,PMEPA1,SHD,STMN4" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_1000 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.18E-06 6.03E-03 8.29E-06 7.55E-05 191 844 "DGCR6,ABCF1,ACLY,KDM5D,ARID1A,ADD1,KIDINS220,AK2,OGT,LCORL,EPB41L5,APLP1,DGKZ,CASK,ASCL1,DDX3Y,TMEM108,BACH1,MYRF,BTRC,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,INA,ARHGEF1,ARHGEF2,CDC42,LHX2,FADS2,COL9A1,RBM39,CRMP1,HAPLN1,RNF14,CLIP3,CSNK1E,CTNND1,PUM1,ARHGAP32,TCAF1,DAPK1,SCRN1,DAPK3,DBI,DBN1,DCTN1,BLOC1S6,GSDME,SACS,RCAN1,DNM1L,EDNRA,MBNL2,EIF4G1,ELAVL4,PLEKHO1,EPB41L2,WAC,FABP7,TUBB3,SEC24B,FER,FGFR1,MEX3B,SYNCRIP,FOXM1,DPYSL4,PDLIM5,STAMBP,DLL3,NEK6,GAP43,GART,TCERG1,TOX3,KIAA1958,OS9,GNG3,GPM6B,LPAR4,STMN2,GRB10,BACH2,SMAP1,C5orf24,NKD1,INSM1,TUBB2B,KIF2A,KLC1,SMAD1,MAPT,MDFI,CHIC1,MEF2C,SESN3,TAGLN3,NASP,NCAM1,NEFM,NFYA,NNAT,PDGFRA,GPR85,GNG2,OLA1,PIK3R1,PKM,PCDH18,RC3H2,EXOSC10,SH3KBP1,PPP2R5E,PRKACB,ZIK1,PTPRG,PEX5,NKAIN1,GAL3ST4,UBR7,ZFHX4,MEG3,ATAT1,ZNF354C,ATXN2,SEC14L1,SFPQ,SUPT20H,SCG5,ITSN1,ARX,SHMT2,ST6GAL1,WDR37,ZKSCAN3,SMARCA4,SNAP25,SNRPN,SON,SOX2,SOX5,ZCCHC24,SOX11,CAND2,RBM26,SPART,TROVE2,SULF2,GSE1,SYT11,JMJD6,PJA1,FBXW11,KLHL4,TRIM2,TCF12,USP22,CLASP1,PUM2,TIE1,TMEM9,ASXL3,TMPO,TNS1,RBFOX2,STXBP4,ZMYND8,TSC2,SSBP2,TST,UBTF,UCHL1,PITPNB,USP1,SF1,ZFP37,ZIC1,ZIC3,ZFAND5,MEIS3,INTS3,STOX2,CIAPIN1,VPS35L,PCBP4,RTN4,VANGL2,ADAMTS10" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_1000 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.19E-06 6.06E-03 8.31E-06 7.58E-05 48 148 "NCKAP5,GRAMD1B,LTBP4,GPAM,APOC1,ATP1A3,CBLN1,SCARB1,CD81,LGI1,DLGAP1,RAB33A,FADS2,TCAF1,ARMCX2,ZEB2,ABCC9,EDNRA,HEYL,EGFR,DLC1,TMEM164,ALDH1L1,FREM1,GRB10,GUCY1A1,HMGCR,KCNJ3,LSS,NPY,PCDH9,PDGFRA,PLIN1,FXYD1,PLTP,FAT3,LAMA1,STK32A,SLC6A15,ROBO2,PPM1E,ACSBG1,ARHGEF9,TGFBR3,HHIP,HEY2,VSNL1,STOX2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.21E-06 6.15E-03 8.42E-06 7.67E-05 24 54 "CBLN1,INA,LHX2,SLITRK5,ST8SIA3,SEZ6,PIPOX,REEP2,TUBB4A,FOXM1,GABRB3,GLDC,TOX3,CECR2,STMN2,SHISAL1,NRCAM,SALL1,MAPK12,SNRPN,SOX2,ROBO3,WASHC4,SLAIN1" Coexpression Atlas Arv_SC-HD_500_K3 AravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 1.21E-06 6.15E-03 8.42E-06 7.67E-05 75 268 "SYN3,TMEM132B,NLGN4X,PDZD4,KIF1A,SYT6,MAP7,CLDN10,CHGA,FAM19A5,IGLON5,COL9A1,GAL3ST1,TCEAL2,RIMS4,RIMS3,FAM57B,LINC00599,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,SYT3,B3GAT1,MEGF10,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GRIA4,GRM3,IGSF21,C1orf94,IGFBPL1,SHISA6,CELF5,ATCAY,BTBD17,IGSF1,KCNQ2,FGFBP3,CPNE9,SCG3,DDX25,NNAT,ZDHHC22,GDAP1L1,CAMKV,PPP2R2B,RAB39A,GDPD2,TMEM145,NKAIN1,RIMKLA,PPM1E,SLC1A6,TMEM132D,SNCB,LHFPL4,ZFR2,COBL,TAC3,CHST8,ENHO,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,CADM2,GAL3ST3,JPH3" Coexpression Atlas GSM399400_500 "alpha beta T cells, T.DPsm.Th, 4+ 8+ TCR-/lo FSClo, Thymus, avg-3" "Immgen.org, GSE15907" 1.22E-06 6.19E-03 8.46E-06 7.71E-05 91 343 "FMNL2,ADCY6,RNF157,PITPNM2,SEMA7A,DGKD,MIER1,ARNTL,RASL11B,ALDH7A1,BACH1,LDLRAD4,CACNA1E,CAPN3,RCBTB2,CNN3,WHRN,AKAP12,LRIG1,CSNK1E,TOX,LONRF1,DGKG,DAPK1,DNAJC6,DLG4,NYAP1,USP3,ABCC5,RASGRP1,LPAR6,PAN3,USPL1,EPB41,SLC43A2,IP6K2,NSG2,OGA,ARPP21,GPR162,DCLK2,TDRKH,MAP4K5,HMGB1,NIM1K,TUBB2B,KCNH2,LIG4,AQP11,LDLRAD3,AFF1,XRRA1,ZC3H12B,PDE4D,XRN1,PLCL1,SLC25A23,SPATA6,SH3KBP1,POU6F1,VPS13C,RIPOR1,CEP97,ZDHHC14,PCMTD2,SATB1,SCN4B,MAGI3,ST8SIA1,DZIP1,ANKRD6,SLA,TET1,SMARCA4,TNIK,KDM3A,SMOC1,MPRIP,GSE1,VAMP1,ANKRD28,SLC37A2,TCF7,TCF12,PRRT1,TNS1,SSBP2,LMAN2L,NAV2,MVB12B,NHSL1" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_100 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_100 FaceBase_RNAseq 1.25E-06 6.39E-03 8.72E-06 7.95E-05 36 99 "ERMN,TTLL9,CA4,CBLN1,INA,LHX2,ST8SIA3,ELAVL2,ADGRV1,REEP2,TUBB4A,GABRB3,ILDR2,SALL3,GLDC,TOX3,MAP7D2,CECR2,STMN2,SOX21,USP51,SHISAL1,CDH20,NRCAM,IGSF11,PAX6,PRTG,FEZF2,SALL1,SNRPN,SOX2,C11orf87,AJAP1,ZIC2,DPYSL5,CA10" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_250 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_250 FaceBase_ST1 1.28E-06 6.51E-03 8.87E-06 8.08E-05 59 196 "TTYH1,C3orf14,NR0B1,TAOK1,JAM2,RAB33A,NECTIN3,FEZ1,KATNAL2,ZFYVE16,SCRN1,OLIG1,ELAVL4,KATNAL1,FABP7,EFCAB2,CSPG5,STAU2,C15orf41,RAB30,GPM6A,TDRKH,CACFD1,MFSD2A,IGFBPL1,LIX1,TUBB2B,PACRG,SCG3,RSPO2,NEUROD1,PAX6,MINDY2,PPP2R5E,GDPD1,FEZF2,SLC25A36,PBRM1,ARMH4,CCDC112,SCN2A,LINC00461,HSPA4L,SCG5,KIF21A,SOX2,NPAS3,SYT11,NUDT10,ADAMTS17,CCDC173,NR2E1,NPL,PRMT8,TRPS1,FAM181B,XRCC4,ZIC1,GOPC" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K3 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.28E-06 6.53E-03 8.88E-06 8.09E-05 110 435 "ACTN2,SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ZFYVE28,ARRB2,PDE8B,ATP1A3,MTMR9,BARD1,NRP2,KSR1,IL33,LDLRAD4,CFAP410,CAMK2A,CAMK2B,REPS2,KCNAB3,CLU,SLC24A2,BAG4,CREM,HAPLN1,CRYBB1,MICAL2,PLCH2,TIAM2,DLG2,SNX29,TMTC1,RASA4,RASGRP2,SEZ6,EPS8,NCALD,CDKL3,PTK2B,ZMYND15,DLL3,ABLIM2,FYB1,ARPP21,TMEM8B,LYVE1,NTNG2,GNG4,ADAP1,GRK4,GRIA1,GSN,TMEM25,GUCY1B1,SCIN,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MITF,MOBP,BCO1,MYH3,MYO6,NPR2,OPCML,ETFRF1,PDE4B,PDE4D,ENPP2,PDPK1,PILRA,NXPH1,PRKAR1B,MASP1,GDPD2,STRC,RAB3IL1,PID1,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,KCNIP3,SH3GL2,ASAP3,CCDC92,SLC1A2,SLC6A9,SLCO1A2,INAVA,C11orf87,SAMSN1,ACSBG1,TMOD1,FLRT2,MICU3,EML6,LAMP5,CADM2,LRP8,PCDH15,DNAH10,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.33E-06 6.77E-03 9.20E-06 8.38E-05 65 223 "ABAT,FMNL2,KLHL13,NR0B1,KCNT1,CACHD1,PPP4R4,ATP2B3,WASF1,CACNB2,CALB1,SLC16A4,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,TMEM35A,EMX2,EPB41L1,PCYOX1,GABRA4,GALC,PCDH11X,PACSIN2,SHISA6,KLHL23,KITLG,CCDC80,MYO9A,NFIA,NUCB2,ETFRF1,SERPINI1,SEMA5B,PPARA,PPP3CC,REV3L,ZFHX4,TMEM206,LGR4,HUNK,RASA3,FRMPD1,ST8SIA1,SLC4A3,UHRF1BP1L,SMOC1,ST5,SLC37A2,ADGRL3,DOCK9,OBSL1,DNAH7,ACTR6,TNNT1,FNDC5,VAV2,ZNF23,ELFN1,NAV2,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.38E-06 7.03E-03 9.54E-06 8.69E-05 107 421 "EMILIN3,ADD3,HECW2,C1QTNF1,TRMT9B,AMPD3,LRCH2,RNF182,NRP2,SGCE,LDLRAD4,RUNX1T1,NEURL1,CDH2,CDH10,MAGI1,RCBTB2,ZBED5,SLIT2,AKAP5,FAM171B,CRHBP,HAPLN1,BRINP1,AK5,DNM2,EDIL3,FRY,EML1,EPHB1,ETV1,MRVI1,TMEM132C,CORO2B,FOXF2,FLT1,SPECC1,PNMA2,DKK3,MEGF10,GABRA3,GABRA4,CHL1,GABRB1,GABRB3,PCDH17,LYVE1,PCDH11X,B4GALNT4,GPR37,RAPGEF4,STMN2,PARD3B,GRIN2C,RASSF8,HLF,NEGR1,IRF8,IFI16,KCNK2,KIT,IL17D,RSPO2,MYO6,NAP1L2,NASP,NDP,HCN1,DDR2,PDE1A,PDE4B,PCDH18,PMP22,MAGEL2,PRKCB,PTPRB,RGS4,ZFHX4,C12orf49,ELMOD1,TRA2B,DOCK10,SPHKAP,LIMCH1,NPAS3,C11orf87,CLASP2,EPB41L3,NEK4,COBL,ANO4,PCDHB7,ZFPM2,HHIP,THBS4,TMPO,TNNT1,RBFOX2,TPM1,SYNPO2,TRO,TMEFF2,RPRM,PLPPR5,STOX2,ACTR3B,MSRB3" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000 kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.42E-06 7.26E-03 9.84E-06 8.97E-05 55 179 "NDRG2,SPARCL1,ALDH7A1,MYOM1,CACNA2D1,CACNB2,DCLK1,NDST3,ARHGEF6,CP,RGS6,DGKB,CCDC3,DMD,ABCC9,EBF1,EDIL3,EDNRA,HEYL,FRY,RCAN2,DLC1,FHL1,CAP2,TUBA8,GNAO1,GUCY1A2,GUCY1A1,GUCY1B1,TCEAL6,HSPA1L,SLC6A17,LRRTM3,MEF2C,PDE3A,ABCB1,SERPINE2,SERPINI1,PLCL1,FXYD1,SEPT4,RELN,SYTL2,FIGN,RERGL,STUM,SLC4A3,SLC8A1,SLC12A2,CPEB4,HEY2,TNS1,TPM2,TRPC1,RGS7BP" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_cfr-2X-p05 Pluripotent Stem Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.44E-06 7.33E-03 9.91E-06 9.04E-05 184 810 "TTYH1,TMEM132B,ADD2,NLGN4X,OSBPL1A,WDR35,SEMA6A,CNIH2,APLP1,VAT1L,ALDH4A1,ATP1A2,ATP1A3,ADAM15,BLM,PROM1,DIRAS1,PTBP2,SYT6,CBR1,CLDN10,LDB2,DCLK1,MAGI1,CDO1,UBE2L6,FOXN3,CHN1,CLU,TJP2,PCYT1B,TCEAL2,IGDCC3,NECTIN3,AKAP12,CRMP1,CRYM,RIMS4,FAM131B,ECE2,TOX,BRINP1,JAKMIP2,ALKBH8,SACS,SV2A,G3BP2,RABGAP1L,CHRDL1,FAM57B,DPYSL2,DNAJB6,FARSB,EDIL3,EDNRB,CACNG7,AASS,LINC00599,ANKRD13B,ERBB2,PIPOX,ECSIT,FABP7,ACSL4,FDFT1,PPP1R1B,ZNF589,OLFM1,POLR1B,MAD2L2,FHL1,SEMA4D,FLT1,NBEA,TACC2,SORBS1,NSG1,MPP6,MEGF10,JPH4,IQGAP2,GAP43,GART,SESN1,RND1,GLDC,DBF4,GLI2,GNG4,GPR19,GRIK5,KAT7,MFSD2A,SOX21,LINGO1,PSIP1,HMGCR,C9orf129,CPT1C,ATCAY,ZIC5,RBPJ,IGSF1,KCNN2,KCNQ2,KIF5A,FGFBP3,LSS,SCAMP5,MID1,MMP17,MPP2,SESN3,SCG3,DDX25,MYCN,MIR4697HG,NAP1L2,NAP1L3,NASP,NEFM,NELL2,NPTX2,ZDHHC22,PBX1,CDK14,CAMKV,PIK3CD,PCDH18,PSAT1,EPB41L4B,FSD1,PPM1B,PPP2R2B,PKIA,GDPD2,PTN,PTPRZ1,NKAIN1,ARHGEF10L,ROBO1,TUNAR,CCDC112,DRAXIN,SCG5,SEPHS1,CCDC88A,OGDHL,SNRPN,PDZRN3,TRERF1,SOX2,TNIK,SP4,SPP1,UNC5B,ZNF423,FCHO1,NCDN,PHLDB1,SEPT3,STXBP1,KLHL7,RHBDL3,ARHGEF9,SYT1,COBL,TAC3,MTCL1,UNC5D,WWC1,WSCD1,TCF4,ENHO,RELL2,ZMYND8,UGT8,VSNL1,TCEAL7,ZFAND5,SLC38A1,GAL3ST3,NAV2,PDSS2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.53E-06 7.79E-03 1.05E-05 9.59E-05 13 20 "CNTFR,CLIP3,FEZ1,CACNG7,NSG1,GFRA2,ACOT7,TAGLN3,NNAT,SERPINE2,PRPH,SST,UCHL1" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Lungmap CCHMC 1.53E-06 7.80E-03 1.05E-05 9.59E-05 106 417 "ABAT,ACTN1,NDRG2,ADCY2,WDR35,SPARCL1,LCORL,APBB1,CASK,CHRD,ATP1A2,BCHE,DST,SYNJ2,CACNA1G,CACNB2,RUNX1T1,DCLK1,NOG,COL9A2,ABI3BP,FAM171B,CLIP3,TENM4,GPSM1,RIPOR2,RCAN1,EDNRB,TMTC1,LRRC17,NCALD,ETV1,F3,FCGRT,FOXF2,USP16,DKK3,MEGF10,GHR,SPIN1,GPER1,GRB10,NR3C1,PRDM5,ADAMTS6,GUCY1A1,GUCY1B1,WIF1,GPR45,HPSE2,CPT1C,IGF1,NKD1,KCNK3,KCNMA1,KCNN2,TTYH2,LAMA2,LDLRAD3,MEIS1,SAMD14,NFIX,NNAT,DDR2,PALM,PDGFRA,ENPP2,PENK,SERPINE2,BCAS3,PTCH1,PTH1R,RGS4,ROBO1,ROBO2,TMEM100,LGR4,SEMA6D,TNFRSF19,NLGN1,DZIP1,SIRT2,TRIM67,TET1,PALLD,FAM126B,SOX5,ZHX3,ERC1,KIF1B,PHLDB1,STX1A,KANK1,SULF2,TCF7,TGFBR3,HHIP,TPM1,TPM2,SYNPO2,TRPS1,ZKSCAN5,VSNL1,PMEPA1,MSRB3,ADAMTS10" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap CCHMC 1.56E-06 7.96E-03 1.07E-05 9.77E-05 95 364 "DPF1,NCKAP5,NDRG2,ADD1,ALCAM,ABCD2,OGT,APBB2,APOC1,PPP4R4,DYNLL1,MTMR3,CACNA1G,CACNB4,CAST,CLDN10,SEPT7,CDO1,ABCG2,RBM39,CNTNAP2,PPP1R16B,MYADM,DAPK1,GIT2,DMPK,RCAN1,DTNA,ABCC5,SIDT2,FAM13A,PLEKHA1,RGS17,PCOLCE2,CALCRL,RASGRP2,WAC,CHST15,GAD2,CPLX2,GHR,GLUL,GOLGB1,STON1,PARD3B,ADAMTS8,GSN,IRF8,IL6R,IL6ST,KCNA2,MAN2A2,MAPT,MEIS1,NELL2,NRCAM,NTRK2,PIK3R1,SMOX,FXYD1,FITM2,VPS13C,MTMR10,PYGM,PID1,ACSS3,SH3TC2,SUGCT,ROBO2,RYR3,SCN7A,FNIP1,ZFP30,SLC1A3,PREX2,SLC12A2,ZCCHC24,NXT2,FGD4,TCF7L2,PCDHGA6,SYNE1,HIF3A,ATP13A2,TGFBR3,CADM1,FRRS1L,PLEKHH2,VIPR2,LYPD6,ZBTB16,SLC38A1,GAL3ST3,CERS6,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000 DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.60E-06 8.13E-03 1.10E-05 9.98E-05 177 775 "RALGAPA1,ABHD6,OSBPL6,TAOK1,FAM135A,AMPD3,OGT,ANK3,APAF1,APC,EPB41L5,DGKD,TNRC6C,AQP4,PDE8B,SLC4A4,GPR146,CFLAR,BMPR1B,WASF1,CA4,CA8,CACNA1D,CACNA2D1,CALB1,CANX,MAP7,RGN,LRBA,DCLK1,CFL2,B4GALT6,SLIT2,CLCN3,FAM149A,COL4A5,NECTIN3,SLC35F1,RBM39,OSBPL3,IPCEF1,PLCH2,DZIP3,CTH,ARHGAP32,ARHGAP24,AIF1L,MFAP3L,PLPPR4,PDCD6IP,SEMA3D,EIF5,IRAK4,TENM1,EMX2,ENO2,SLC43A2,EZH1,EFEMP1,ATP8A1,ST3GAL6,MED12L,KIAA1109,SPSB4,SUCO,SYNCRIP,C2orf88,SMC2,PDLIM5,CAMKK2,PHYHIPL,DKK3,AHCYL1,GALC,RAPGEF6,IQGAP2,SYT17,IGSF5,TUBGCP4,SRCAP,GFRA1,GHR,PPARGC1A,GJB1,GK,GLS,CNDP1,GRB10,GRIK2,TMEM25,PADI2,ICA1,SCIN,IL6ST,TUBB2B,SLC35G1,KCNC2,KCNJ10,KCNJ16,KCNK1,KIF2A,L1CAM,NCOA7,AQP11,CHIC1,KITLG,MKLN1,MYO6,VWA2,PENK,PFKFB2,PIK3C2A,PSAT1,SCHIP1,PMS2,DRAM2,KANSL1,PKN2,MAPK4,MAPK8,EML5,FAM184A,RASGRF2,VEPH1,RET,REV3L,RFX5,TTLL7,PRR5L,SALL1,SCN8A,LINC00461,SOX6,SFPQ,ASRGL1,TRA2B,PPP1R9A,HKDC1,RUFY2,SLC8A1,NAPB,SLC15A2,SCMH1,LIMCH1,FAM126B,BDP1,ZHX3,MYCBP2,ATP10B,KANK1,FGD4,PRRC2C,VPS13A,NUDT10,TMEM150C,CAMSAP2,WWC1,MGRN1,CUX2,WASHC4,ZFP91,ERCC6L2,RBFOX2,RGMB,DCBLD1,SSBP2,RPRM,UGT8,VLDLR,FMN2,EMX2OS,LYPD6,DOCK8,NUP214,NETO2,SOCS4,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_anlage of loop of Henle_1000 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.64E-06 8.34E-03 1.12E-05 1.02E-04 181 796 "RALGAPA1,ABHD6,PLEKHH1,BEND6,OSBPL6,DOC2A,OGT,ANK3,C6orf89,APC,EPB41L5,DGKD,PHYHD1,TNRC6C,ATP1A1,SLC4A4,CFLAR,PROM1,BMP7,DST,MTMR3,CA4,CACNA2D1,CALB1,CANX,MAP7,CLDN10,USP2,DCLK1,CFL2,CLCN3,NMT2,COL4A5,GAL3ST1,NCOR1,CRYM,GREB1,EDRF1,TM9SF4,TMEM170A,ZEB2,MFAP3L,BLOC1S6,NTM,ARNT2,KBTBD11,DNM2,CPEB2,DUSP9,DNM1L,GOLT1B,SGK2,HIPK3,SEMA3D,EIF5,EMX2,VPS13B,CDHR1,EZH1,ST3GAL6,SEC24B,MED12L,KIAA1109,FGF1,SPSB4,SUCO,SYNCRIP,SGIP1,SMC2,PDLIM5,DKK3,GABRA1,GALC,RAPGEF6,IQGAP2,SYT17,IGSF5,GCNT2,GFRA1,PPARGC1A,KIAA1958,CECR2,GRB10,TMEM25,FAM107A,ZHX1,IGFBP1,SCIN,TUBB2B,KCNC2,KCNJ10,KCNJ16,KCNK1,KIF2A,LIMS1,NCOA7,CLEC18A,CHIC1,MEIS1,MID1,MITF,MKLN1,MYH3,NASP,NCAM1,CNOT4,NRCAM,OXTR,CNTN3,PDE1C,ENPP2,PENK,PFKP,PIK3C2A,PDZRN4,RC3H2,SCHIP1,PMS2,PRRX1,KANSL1,MAPK4,MAPK8,RELN,CNNM2,LAMA1,PTPRO,RASGRF1,REV3L,ROBO2,NCBP3,SALL1,SCN7A,SCN8A,ZFP2,FHOD3,RUFY2,NAPB,SLC15A2,EFHD1,SLCO1A2,CPEB4,SORCS3,FAM126B,ZHX3,MYCBP2,KIF1B,DDN,EPB41L3,NEK4,STX1A,KANK1,PRRC2C,ARHGEF9,VPS13A,DNMBP,CAMSAP2,WWC1,MGRN1,WSCD1,SATB2,TRIM2,WASHC4,NSD1,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,UGT8,VLDLR,EMX2OS,SHD,ADAMTS9,TMEM178A,GOPC,DOCK8,NUP214,MSRB3,NETO2,SOCS4,SPATA13" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 facebase_RNAseq_e10.5_Emin_LatNas_2500_K2 Gudmap RNAseq 1.66E-06 8.44E-03 1.13E-05 1.03E-04 37 104 "TTYH1,ADD2,JAM2,NRXN3,IQCK,IGDCC3,ELAVL2,ELAVL4,ERBB4,ADGRV1,FABP7,TUBB4A,AFF2,TUBA8,GPM6A,GPM6B,GRIK2,RNF165,GUCY1A2,CELF3,KCNJ5,KCNJ16,KIF5C,MAP2,MAP6,NEFM,NOVA2,ELOVL2,RTN1,HSPA4L,PREX2,SNAP25,INKA2,WNT7A,ZBTB16,LRP8,AP3B2" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_1000 dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.67E-06 8.52E-03 1.14E-05 1.04E-04 185 817 "CCDC85A,ADORA2A,HECW2,NR0B1,ADGRF5,SPARCL1,SEMA6A,SEMA7A,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBB2,DGKZ,SHROOM2,ARRB1,MARK4,ATP1B3,DOCK11,ADAM15,BACH1,NRP2,ARHGEF7,C1QC,LDLRAD4,THSD7A,SPAG9,LDB2,FMNL3,SCARB1,CD38,MS4A7,JAM2,ABCG2,TMEM184B,MAP4K4,LY86,CNN3,ZNF521,CDC42BPB,CREB5,CRMP1,HAPLN1,ABCG1,CSF1R,PPP1R16B,CX3CR1,CYBB,DOCK4,TOX,KIAA0513,RASSF2,GIT2,DBN1,ARMCX4,PITPNC1,ELMO1,FAM107B,CCDC3,GNE,ECM2,FAM78B,EBF1,EDIL3,EDNRB,YAF2,SH3GLB1,MBNL2,LPAR6,PLEKHA1,CALCRL,PAN3,PLEKHO1,RASGRP2,STX2,DENND4A,RCSD1,FAM198B,CORO2B,DLC1,CHST15,KIAA1109,FLT1,UFM1,PDLIM5,TRIM16,FYB1,FYN,NEK6,GAP43,PCDH17,GGTA1P,HPGDS,GLUL,LILRB4,ATF7,LPAR4,RAPGEF4,STMN2,MAP4K5,NCKAP1L,ZDHHC15,ICA1,IGF1,ITPKB,KIT,INSYN2,LMO2,TM6SF1,MEF2C,MEST,KITLG,LAYN,MYO6,CLEC9A,OPHN1,PALM,PDE2A,PDE4B,PDE4D,GNG2,PIK3R1,PLCL1,SCHIP1,SPATA6,DRAM2,MAPK3,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,ROBO1,SEMA6D,RASA3,SGK1,FAM102A,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,UNC5B,PEG10,ZNF423,COLGALT2,SAMSN1,THSD1,RGL1,ADHFE1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,ZEB1,DOCK9,TEK,TF,C18orf54,TIE1,HEY1,TJP1,TLR4,TRPC3,DCBLD1,RFTN2,TTPA,WIPF1,ZNF711,PMEPA1,GDPD5,STOX2,ADAMTS9,NAV3,FAM13C,DOCK8,ST7,MSRB3,NHSL1,ZDHHC20,RNF146,SPATA13" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.68E-06 8.58E-03 1.15E-05 1.05E-04 29 73 "RUNX1T1,CDH10,EBF1,SEMA3D,ELAVL2,EFEMP1,GFRA2,GLRB,KCND2,MATN2,MEIS2,CLDN11,PCDH8,PDGFRA,PIK3R1,PRRX1,MED1,PTPRD,FAT4,LGI2,MEG3,CSRNP3,FAM19A1,MTERF2,TROVE2,ANO4,TEX15,ZFPM2,HHIP" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K3 facebase_RNAseq_e10.5_Emin_LatNas_2500_K3 Gudmap RNAseq 1.79E-06 9.14E-03 1.22E-05 1.11E-04 268 1257 "DPF1,ABCF1,ACLY,ARID1A,FMNL2,KIAA1211,SEMA6A,CEP126,LRCH2,ANK2,APC,UPRT,ARHGAP5,ASTN1,ATM,ATP6V0A1,KIF1A,BLM,ZNF599,CFLAR,PROM1,FUBP1,WASF1,CA12,CACNB2,PTBP2,CANX,USP2,CDK11B,SEPT7,CDC27,CDH2,SRSF11,CHN1,KIAA1549L,FAM19A5,C4orf33,QKI,NIPBL,CNTFR,AKAP7,BTF3L4,SLC4A7,SLC4A8,AHCTF1,SLC35F1,FAM171B,CREB5,CRMP1,CLIP3,IPCEF1,CNTNAP2,FAM169A,DZIP3,PHF14,BOC,FGFR1OP2,KATNAL2,TOX,LIN54,KIAA0586,AIF1L,DDX46,MTX3,DMD,USP3,SLC29A4,CASP8AP2,DTNA,E2F5,FSD1L,EIF4G2,EIF5,PLEKHO1,EPB41,COQ7,ANKRD13B,SRRM1,ERCC2,CEP85L,ETV1,TLR7,CEND1,NSRP1,WAC,CORO2B,FKTN,FDFT1,SPSB4,CAMSAP1,FHL1,MEX3B,NOP56,COQ5,ZCCHC17,SMC2,USP16,PRELID3A,KHDRBS3,FUT9,PHYHIPL,MTHFD2,ACSS1,GART,KIAA1841,GFRA2,GK,TCERG1,DBF4,GLI2,GLRB,TOX3,CBX1,GNAO1,GNG3,GRK4,CNTRL,STMN2,CIT,MFSD2A,PSIP1,BACH2,HMGCR,HSF2,HSP90AA1,SMAP1,DOCK7,LRRCC1,LIX1,TUBB2B,KIF2A,KTN1,LIG4,SFXN5,LMO1,HECTD2,LSS,MARK3,TM6SF1,MID1,POC1B,TAGLN3,MYO5A,NAP1L1,NASP,CNOT4,CLEC9A,NRCAM,NRDC,ODF2,PAK3,PDE3B,PDE1B,FAM98B,OLA1,ANLN,GPSM2,PPP1R1A,CRLS1,PKIA,MAPK8,LRRC49,CNTLN,SPDL1,ZIK1,EML5,PTPRZ1,PTX3,CCDC40,FAM184A,ARID4A,RBBP6,RBBP8,RADX,VEPH1,RDX,REV3L,ERI2,SETD5,MYH14,FBXW7,CLIP1,FAM19A1,SCN8A,ZFP2,SOX6,SFPQ,TRA2B,ZFP30,KIF21A,PPM1E,CHD9,FHOD3,ST3GAL3,ST8SIA1,DHX30,RUFY2,PKNOX2,YPEL4,CCDC88A,SHANK2,ZNF334,EFHD1,TET1,SMARCE1,MBD5,ANKFN1,KDM4B,SOX5,BDP1,SP4,SPP1,ZC3H13,RBM26,POGZ,ZSCAN29,SEPT3,ACSBG1,SYT11,SYNE2,VPS13A,DNAJC9,SYP,ANKRD28,TAF9,WSCD1,ZEB1,TCF12,CLASP1,NSD1,PUM2,DICER1,SIRT1,C18orf54,ITGB3BP,AKTIP,RELL2,TMPO,R3HDM1,PIK3R5,TP53BP1,TPM3,C9orf85,TPM4,PDSS1,STXBP4,TRPS1,USP1,NSD2,XPO1,ZNF711,ZNF23,KCNT2,ZFP41,REEP1,ZNF184,SPIRE1,SMARCAD1,EMSY,EVI5,TUBA1A,FIP1L1,WNK3,FZD3,MRPL47,IFT88,NETO2,ST8SIA2" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_FlankLateral_100 e10.5_NeuroEpith_FlankLateral_top-relative-expression-ranked_100 FaceBase_ST1 1.82E-06 9.26E-03 1.24E-05 1.13E-04 30 77 "TTYH1,NR0B1,JAM2,FEZ1,SCRN1,FABP7,CSPG5,C15orf41,GPM6A,TDRKH,MFSD2A,IGFBPL1,TUBB2B,PACRG,SCG3,RSPO2,NEUROD1,PAX6,MINDY2,FEZF2,PBRM1,SCN2A,LINC00461,HSPA4L,KIF21A,SOX2,NPAS3,CCDC173,NR2E1,FAM181B" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k5_500 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.83E-06 9.32E-03 1.24E-05 1.13E-04 48 150 "PNMA8B,LCORL,PKP4,ATP2B1,BACH1,RUNX1T1,ZNF445,SRSF11,CHM,RBM39,TENM4,FGFR1OP2,AIF1L,ZEB2,ZC3H11A,EDNRA,EIF4G1,EPB41L2,SRRM1,SMC2,LPAR4,MAP4,CHIC1,MEIS1,MEIS2,MID1,MSI1,NASP,PCSK5,MAPK8,TMEM255A,TMLHE,MEG3,ATXN2,TRA2B,SLC12A2,TET1,ZC3H13,KIF1B,PRRC2C,SYNE2,CBX5,R3HDM1,SSBP2,FLRT2,NAV2,SNX27,GAN" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.90E-06 9.68E-03 1.29E-05 1.17E-04 144 608 "ABAT,EMILIN3,CCDC85A,RTL9,DISP3,SEMA6A,ANK1,KCNAB2,CDK10,IGDCC4,SPTBN4,RASL11B,BMPR1B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,LRBA,CDO1,CRLF1,CLTB,NIPBL,COL9A2,COL9A3,SLC4A7,ABI3BP,IGDCC3,ANKRD44,CLIP3,SNCAIP,ATRNL1,BOC,ARHGAP24,RHOBTB1,GRIN3A,DNM1,ABCC9,MBNL2,EPB41,EPB41L1,LRRC17,DENND4A,HSPA12B,FCGRT,FDFT1,TESK2,SCARA3,FOXF2,AFF2,NBEA,TRIM16,NSG1,STAU2,TVP23A,ZMAT1,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,WIF1,BACH2,SYNPO,IL11RA,INPP1,JAK2,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,TM6SF1,MEIS2,SRSF12,MSR1,N6AMT1,RSPO2,FXYD7,NFIX,NPY,NRGN,ODF2,ZNF827,CNTN3,PDE3A,PDE4D,PFKFB2,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,ZFHX4,MRAP2,BAALC,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SMARCC2,RCOR3,DOP1A,CDK19,EPB41L3,DIP2A,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPC3,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,NAV3,CERS6,SSPN,KLHDC1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.92E-06 9.81E-03 1.31E-05 1.19E-04 18 35 "DPP10,CADPS,ASTN1,CACNA1B,CDH10,GRIN3A,DACH2,GRM7,FAM19A2,RSPO2,NAP1L2,CLDN11,GPR85,SCN3A,ST8SIA1,NPAS3,CUX2,RPRM" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.94E-06 9.90E-03 1.32E-05 1.20E-04 99 385 "EMILIN3,ACTN2,ADCY2,KIAA1324,SRPX,ARHGAP20,CDK10,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,REPS2,KCNAB3,CDO1,CRLF1,COL9A2,ABI3BP,ANKRD44,CSF1R,CCDC3,DLG2,DRP2,ABCC9,RASA4,ELN,EPB41L1,LRRC17,EPS8,FCGRT,TRIM16,TPK1,TVP23A,FYB1,ARPP21,TMEM8B,ZNF276,GNG4,GSN,WIF1,SYNPO,IL11RA,CREG2,VWA5A,GPR155,MBNL1,SRSF12,CD200,TCEAL5,NELL1,NFIA,NFIX,NPR2,CLEC9A,CNTN3,PDE4D,PLCL1,TRHDE,PRRX1,SDK2,EPB41L4B,NXPH1,PRKAR1B,CNTLN,ACSS3,IQSEC3,ZCWPW1,ZNF493,BEND5,ZMAT4,ZFHX4,MYH14,LRRK2,DGLUCY,ATXN1,MRAS,SH3GL3,ASAP3,DOCK10,SLC1A2,SLC6A9,SLC8A1,LIMCH1,PDZRN3,TNIK,UNC5D,ADGRL3,SATB2,PHF24,TMOD1,SYNPO2,TRPS1,TSPAN11,LAMP5,PMEPA1,CADM2,PCDH15,DPF3" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K5 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.99E-06 1.02E-02 1.35E-05 1.23E-04 53 172 "EMILIN3,ADCY2,SEMA6A,ARHGAP20,LGR5,CDK10,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,PCYT1B,ANKRD44,CSF1R,CCDC3,EBF1,ELN,LRRC17,FCGRT,TRIM16,NSG1,FYB1,DKK3,TMEM8B,NTNG2,ZNF276,GSN,RASSF8,HLF,HPSE2,SYNPO,IL11RA,SRSF12,NFIA,NFIX,CNTN3,PDE4D,PLCL1,TRHDE,ACSS3,ZMAT4,ATXN1,DOCK10,ADGRL3,PHF24,TSPAN11,PMEPA1,CADM2,PCDH15" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500_k5 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.13E-06 1.09E-02 1.44E-05 1.31E-04 38 109 "PNMA8B,PKP4,DOCK11,BACH1,SGCE,ZNF445,SRSF11,CHM,SLIT2,RBM39,FGFR1OP2,AIF1L,ZC3H11A,EDNRA,EIF4G1,EMX2,EPB41L2,MEX3B,GABRA4,GABRB1,ILDR2,LPAR4,CHIC1,SAMD5,NASP,CNOT4,PDPK1,C1orf54,RNASEL,TMLHE,SCMH1,ZC3H13,AHCYL2,CBX5,SSBP2,ADAMTS9,SNX27,SENP7" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.16E-06 1.10E-02 1.45E-05 1.32E-04 35 97 "KLHL13,NR0B1,LGR5,CDC14B,PPP4R4,IGDCC4,DCLK1,PLXNA4,DOCK4,DCT,SRGAP3,DRP2,EMX2,MTSS1L,AFF2,GABRA4,TRAF3IP2,PCDH11X,LRRTM3,KCND2,KLHL23,NFIA,PDE1A,REV3L,TMEM206,LGR4,RASA3,ST8SIA1,SLC4A3,SMOC1,ST5,ADGRL3,OBSL1,ZFPM2,WNK3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.16E-06 1.10E-02 1.45E-05 1.32E-04 35 97 "VAT1L,CADPS,INA,CNTFR,CLIP3,CACNG7,ELAVL2,EYA1,FABP7,TUBB3,EFEMP1,GAP43,IGSF5,GFRA2,GNG3,STMN2,HPSE2,SCG3,TAGLN3,NEFM,NFIX,PDGFRA,SLC10A4,PENK,PRRX1,FAT3,PRPH,RTN1,SCG5,SCN3B,SST,CUX2,TMEFF2,UCHL1,STMN4" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.16E-06 1.10E-02 1.46E-05 1.33E-04 36 101 "PNMA8B,TAOK1,LCORL,BACH1,CHM,PLAA,NMT2,RBM39,FGFR1OP2,EIF4G1,EMX2,EPB41L2,SMC2,GABRA4,GABRB1,ILDR2,LPAR4,NR3C1,CHIC1,NASP,CNOT4,PDPK1,TMLHE,FNIP1,TRA2B,SCMH1,ZC3H13,SYNE2,AHCYL2,CBX5,R3HDM1,TSC1,SSBP2,ZNF711,SNX27,GAN" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_500 kidney_P1_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.33E-06 1.19E-02 1.57E-05 1.43E-04 76 277 "RNF157,ALCAM,AMPH,BCHE,BCL7A,BMP7,DST,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,PHF19,SPOCK2,GSDME,SNAP91,ARRDC4,DTNA,EDNRA,ELAVL4,CALCRL,KCNMB2,ETV1,RRAGB,EYA1,ST3GAL6,FGF1,FGFR1,MAD2L2,SCARA3,IGSF5,GFRA1,FREM1,GLRB,TDRKH,CECR2,CNTRL,FAM107A,HAS2,NEGR1,KHK,MEIS2,MEST,MMP16,NCAM1,NELL1,NME4,NPR2,CNTN3,PENK,FAT3,MDGA2,TSPY26P,RAVER2,ROBO2,TMEM100,SALL1,FAM19A1,SLC1A3,SLC4A3,SLC12A2,GKAP1,SULF2,ADAMTS17,CUX2,PCDHB9,TMOD1,TPM2,CADM1,SLC38A1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k1 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.39E-06 1.22E-02 1.60E-05 1.46E-04 58 195 "METAP1D,VAT1L,CASK,ZSCAN18,CACNA2D1,RUNX1T1,ARHGEF25,CDH2,DCLK1,RCBTB2,BTF3L4,ZNF521,CLIP3,GPSM1,DNAL1,RHOBTB1,DYNC1I1,EFNA3,EFNB3,EFS,ADGRV1,UBE2E3,MEX3B,ZBED3,BRD8,GPT2,PSIP1,HAS2,CPT1C,MEIS2,MTR,NAP1L2,FXYD6,ZNF827,GPR173,FTO,PLTP,CEP41,PKIA,TSPY26P,RNASEL,ZFHX4,TMLHE,SATB1,ZNF423,TROVE2,CLSTN2,ZC4H2,SULF2,TCF4,TCF7L2,TEX15,KAT6B,TPM2,CADM1,PARP6,WNK3,RTN4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.45E-06 1.25E-02 1.64E-05 1.50E-04 106 421 "EMILIN3,ADD3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,TMEM263,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,CANX,CDH2,SLIT2,AKAP5,PREPL,NCOR1,VCAN,DZIP3,TM9SF4,ZEB2,PDCD6IP,DYRK1A,EDIL3,EDNRB,HIPK3,SEMA3D,EIF4G1,DCTN4,EPHB1,ETV1,MRVI1,DLC1,KIAA1109,FOXF2,SMC2,PDLIM5,CAMKK2,PNMA2,DKK3,MEGF10,GABRA3,GABRA4,CHL1,GABRB1,AHCYL1,PCDH17,LYVE1,PCDH11X,RAB40B,FERMT2,GPM6B,RAPGEF4,NR3C1,RASSF8,HAS2,IFI16,RBPJ,IL6ST,JAK1,LIMS1,CHIC1,MKLN1,MMP16,SAMD5,NAP1L2,NFIA,NFIX,HCN1,PCDH8,PDE3A,PDE4B,RGS4,ZFHX4,ATXN1,TRA2B,PREX2,SLC14A1,SPHKAP,CPEB4,SOX5,PEG10,NPAS3,C11orf87,COBL,MTCL1,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,ZFPM2,HHIP,ERCC6L2,TNNT1,RBFOX2,RGMB,SYNPO2,TRPS1,WRN,FAM13C,ACTR3B,MSRB3,NETO1" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k1_1000 kidney_P3_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.54E-06 1.30E-02 1.70E-05 1.55E-04 67 236 "ABR,RNF157,MTUS1,TXNDC16,ALCAM,AMPH,CACHD1,ADAM23,BCL7A,BMP7,CACNB4,CDH2,FAM19A5,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,SPOCK2,SNAP91,EDNRA,HEYL,ELAVL4,KCNMB2,ETV1,EYA1,FGFR1,MAD2L2,SCARA3,CAP2,STAU2,GFRA1,GLRB,TDRKH,GRIK4,FAM107A,HAS2,NEGR1,LSAMP,MEIS2,ADAM22,NCAM1,NELL1,NME4,NOS1,CNTN3,PENK,SMOX,FAT3,MDGA2,ZCWPW1,ROBO2,TMEM100,HUNK,SALL1,SLC1A3,GKAP1,SORCS3,SP4,ELOVL4,CAMTA1,TRIM2,PCDHB9,TMOD1,CADM1,LAMP5" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.54E-06 1.30E-02 1.70E-05 1.55E-04 67 236 "ADCY8,ERMN,ALCAM,ATM,BCHE,CBLN1,INA,FOXN3,CLCN3,LRRC3B,HDAC9,MYADM,G3BP2,WDR20,ST8SIA3,RRAGB,CEND1,REEP2,TUBB4A,CEP78,FGF11,SYT3,JPH4,CSDC2,GLDC,TOX3,CECR2,HMGCL,TCEAL6,SHISAL1,ZIC5,CDH20,KHK,MATN2,CD200,CCDC80,PRTG,PDE1A,PENK,NLGN3,ZFYVE21,MAGEL2,NKAIN4,RELN,PTPN13,CCDC40,TSPY26P,STK32B,EMID1,SALL1,MAPK12,SLC4A3,PKNOX2,SNRPN,PALLD,PDZRN3,ADAMTS17,WWC1,WSCD1,WASHC4,FLRT1,ZIC2,ZBTB16,CA10,SHD,SLC38A1,PIANP" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.61E-06 1.33E-02 1.74E-05 1.59E-04 40 118 "PCDH10,SYT13,MIER1,INSYN2B,CH25H,RUNX1T1,CBLN1,DCLK1,CRLF1,PITPNC1,TIAM2,MAGI2,NTM,DLX1,EDNRA,TMEM132C,SYNCRIP,SGIP1,GABRB1,SALL3,GNG4,WIF1,PRRX1,ZFHX4,PRR5L,SALL1,TNFRSF19,SLC15A2,LIMCH1,SOX11,TAC1,UNC5D,TCF4,ZFP91,ERCC6L2,KAT6B,TRPS1,FLRT2,KCNAB1,FRMD6" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.79E-06 1.42E-02 1.86E-05 1.69E-04 51 165 "USP31,TAOK1,APAF1,APC,PHYHD1,BCHE,CACNA2D1,SRSF11,VCAN,DZIP3,MYEF2,DYRK1A,HIPK3,CALCRL,ETV1,DLC1,KIAA1109,PDLIM5,AHCYL1,IQGAP2,GFRA1,PCDH17,PCDH11X,GRIA2,KLF12,HECTD2,CHIC1,MKLN1,MMP16,NCAM2,NFIA,TMOD2,PRRX1,FAT3,SETD5,ST8SIA1,NAPB,SOX5,CLASP2,EPB41L3,AGTPBP1,FBXW11,CLASP1,NSD1,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,WRN,LMAN2L" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_200 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.79E-06 1.42E-02 1.86E-05 1.69E-04 51 165 "FMNL2,NR0B1,SHTN1,LGR5,PPP4R4,PDE8B,INSYN2B,CACNA1D,CALB1,DCLK1,CLU,PLXNA4,DOCK4,DAPK1,MAGI2,DRP2,MRO,EMX2,NRN1,NSG1,GABRA4,GABRB1,GATM,PLD5,KCND2,KLHL23,KITLG,MTR,LAYN,NPR2,PDE1A,ENPP2,CDK14,PCDH18,GDPD2,TMEM206,PRCD,TNFRSF19,STUM,SLC4A3,KDM3A,SMOC1,ST5,ADAMTS17,ADGRL3,ACTR6,DAAM2,FNDC5,LYPD6,WNK3,FRMD6" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_100 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_100 FaceBase_RNAseq 2.83E-06 1.44E-02 1.88E-05 1.71E-04 35 98 "FGF17,CA4,MAP7,CBLN1,INA,IGDCC3,ST8SIA3,ADGRV1,REEP2,ZCCHC17,PHYHIPL,ILDR2,MAP7D2,CECR2,STMN2,SOX21,ZIC5,HES5,AQP11,NRCAM,PRTG,IRX1,GDPD2,RFX4,SALL1,SOX2,BEX1,AJAP1,WWC1,FAM181B,ZIC2,ZIC3,ZBTB16,DPYSL5,NAV2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.83E-06 1.44E-02 1.88E-05 1.71E-04 35 98 "AXIN2,PCDH10,SYT13,CDC14B,MIER1,INSYN2B,RUNX1T1,CBLN1,DCLK1,CRLF1,NTM,DLX1,TMEM132C,SGIP1,GABRB1,FREM1,GNG4,WIF1,SYNPO,PPM1L,ZFHX4,PRR5L,SALL1,FRMPD1,SLC15A2,LIMCH1,SOX11,SYNE2,TAC1,TCF4,KAT6B,TRPS1,WNT7A,KCNAB1,FRMD6" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k4 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.99E-06 1.52E-02 1.98E-05 1.81E-04 50 161 "RNF157,FAM135A,CASK,KALRN,CDH2,RCBTB2,ZNF521,ZFP28,NSL1,PPP1R16B,SPOCK2,BRINP1,SNAP91,EDN3,EFNA3,KCNMB2,GABBR1,GABRA1,CHL1,FREM1,BRD8,GRM3,RNFT2,TOX2,LSAMP,MEIS2,PBX1,EPB41L4B,CEP41,FAT4,GAL3ST4,ZMAT4,TSPY26P,FIGN,SLC25A36,HUNK,CSRNP3,DOCK10,NTNG1,PKNOX2,ZNF334,CLSTN2,STXBP1,ASXL3,TPM2,TTPA,CADM1,XPO1,ZBTB16,NETO2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K2 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.11E-06 1.58E-02 2.06E-05 1.88E-04 152 654 "ABAT,EMILIN3,PLEKHG5,RTL9,SEMA6A,SRPX,ANK1,CACHD1,CDK10,PDXK,IGDCC4,SPTBN4,RASL11B,BMPR1B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDO1,CRLF1,DIS3L,CLTB,PCYT1B,COL9A2,COL9A3,ABI3BP,ENTPD4,ANKRD44,SNCAIP,ATRNL1,BOC,ARHGAP24,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,ABCC9,EBF1,MBNL2,EPB41L1,LRRC17,DENND4A,HSPA12B,EFEMP1,FCGRT,FDFT1,TESK2,SCARA3,FOXF2,SGIP1,TRIM16,NSG1,STAU2,TMEM151A,TRAF3IP2,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,WIF1,RASSF8,BACH2,HLF,SYNPO,IGF1,IL11RA,INPP1,ITPKB,JAK2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,CD200,MSR1,N6AMT1,RSPO2,FXYD7,NDUFA5,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PDGFRA,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,MORC4,RGS10,ZFHX4,MRAP2,BAALC,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SMARCC2,RCOR3,PDZRN3,DOP1A,CDK19,EPB41L3,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,PMEPA1,NAV3,CERS6,ADAMTS10,SSPN" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500 DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.16E-06 1.61E-02 2.09E-05 1.91E-04 99 389 "TKTL1,ADD1,PNMA8B,NR0B1,LCORL,PKP4,LGR5,PDE8B,ASPA,DDX3Y,INSYN2B,DOCK11,BACH1,SYNJ1,SGCE,BTRC,CACNB2,CALB1,ZNF445,SRSF11,CHM,SLIT2,CLU,CNR1,RBM39,DZIP3,PUM1,FGFR1OP2,AIF1L,MAGI2,ZC3H11A,SNAP91,DRP2,EDNRA,RASGRP1,PLXNC1,EIF4G1,ELAVL2,EMX2,EPB41L2,NRN1,SCML2,KIAA1109,MEX3B,GABRA4,GABRB1,ILDR2,GATM,MAP7D2,LPAR4,GRK4,KIF3A,MAEL,KCND2,CHIC1,KITLG,SAMD5,NEXMIF,NASP,CNOT4,GLIPR1L2,PDPK1,SERPINI1,SEMA5B,PLP1,C1orf54,RNASEL,TMLHE,ATP8B4,MEG3,PRCD,FNIP1,TNFRSF19,SFPQ,ARX,SYBU,SCMH1,CPEB4,ZKSCAN3,MYT1L,ZC3H13,LARP4,SYNE2,SLC37A2,DMXL2,AHCYL2,TEX15,CBX5,NR2C2,SSBP2,UGT8,ZNF711,ZNF23,EMX2OS,REEP1,ADAMTS9,SNX27,KLHDC1,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274 Gudmap Mouse MOE430.2 3.25E-06 1.66E-02 2.15E-05 1.96E-04 71 256 "OSBPL8,FAM135A,USP37,TMEFF1,DDX3Y,CACNA1B,PTBP2,CH25H,CDH10,RCBTB2,COL9A1,BTF3L4,LRIG1,CSNK1G3,PDE4DIP,APPL1,PITPNC1,DNAJC6,ZEB2,CEP170,EBF1,EDNRA,SEMA3D,CALCRL,ETV1,FGF13,MEX3B,SYNCRIP,SALL3,DNER,GLS,GPD2,GRM7,MAP4K5,RASSF8,MIER3,LRRCC1,KCNA1,MAP2,NEFM,NFIA,PAK3,NALCN,FAT3,PPP3CB,MAPK8,GRAMD1C,PTPRZ1,KLHL11,RPS20,FNIP1,SFPQ,KIF21A,NTNG1,WDR37,SLC12A2,CMTR2,FAM126B,NPAS3,ADGRL3,TCF4,TRIM2,ZFP91,ERCC6L2,FRRS1L,FLRT2,ZNF711,GOPC,PHTF2,ZDHHC20,SOCS4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.39E-06 1.73E-02 2.24E-05 2.04E-04 51 166 "OGT,LRCH2,LCORL,PDE8B,INSYN2B,CACNA1D,REPS2,AKAP7,PHF14,MAGI2,SRGAP3,DOCK2,TSPAN5,KIAA1109,FGF11,NSG1,GABRB1,SESN1,GRIK3,TCEAL6,IGF1,NKD1,PLD5,LAYN,NEXMIF,NPR2,PDE1A,ENPP2,CDK14,TATDN3,MAPK9,GDPD2,CNTLN,PTPRO,FAT4,RNASEL,SEMA6D,PRCD,STUM,ATF7IP,PDZD2,NPAS3,LHPP,ADAMTS17,TCF12,SZT2,DAAM2,DCBLD1,LYPD6,SSPN,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.49E-06 1.78E-02 2.30E-05 2.10E-04 26 64 "SORCS1,FAM135A,VAT1L,CADPS,RNF182,ADAM23,LDLRAD4,SYNPR,CNR1,EYA1,UBE2E3,SGIP1,DACH2,GRIA2,MAP4K5,NEGR1,LRRTM3,RSPO2,NAP1L2,GPR85,TRHDE,SCN3A,FAM19A1,NTNG1,NPAS3,ELOVL4" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_200_k5 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.67E-06 1.87E-02 2.42E-05 2.20E-04 33 91 "PNMA8B,ATP2B1,BACH1,RUNX1T1,SLIT2,PLAA,COL4A5,ZEB2,ZC3H11A,EIF4G1,EPB41L2,SMC2,PCDH11X,LPAR4,WIF1,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,NASP,PCDH9,PIK3R1,C1orf54,MEG3,TRA2B,ZC3H13,CBX5,R3HDM1,SSBP2,FLRT2,GAN" Coexpression Atlas PCBC_DE_blastocyst_500 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_500 PCBC 3.72E-06 1.90E-02 2.44E-05 2.22E-04 120 494 "KCNH8,ADCY2,NLGN4X,NR0B1,SEMA6A,PCDH10,UNC79,PDZD4,LGR5,SLC7A14,RASL11B,KIF1A,FGF17,CALB1,MAP7,CLDN10,CCKBR,CHGA,DLGAP3,FAM189A2,FAM19A5,IGLON5,COL9A1,GAL3ST1,TCEAL2,TENM4,ATRNL1,IPCEF1,NCAN,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,BRINP1,HS3ST4,CALN1,DPP6,CDHR1,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,B3GAT1,MEGF10,HRASLS5,GABRA5,CHL1,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,CECR2,GSTT2,HAS2,C1orf94,IGFBPL1,SHISA6,TUBB2B,KCND2,CLVS2,KCNQ2,KIF5C,KIT,MOBP,SCG3,DDX25,NNAT,NODAL,GDAP1L1,SEMA5B,JAKMIP1,PDZRN4,PACSIN1,FAT3,PPP2R2B,PPP2R2C,RASGEF1B,RAB39A,RELN,LAMA1,ELOVL2,SLC25A48,FAM184A,RET,PRIMA1,HUNK,RXRG,TMEM200C,SLC1A6,TMEM132D,SOX10,LHFPL4,MCF2L2,ZFR2,SYT4,KLHL4,FAM189A1,LEFTY2,GALNT17,ENHO,CSMD1,PIK3R5,SEZ6L,TRPM2,RPRM,RBFOX3,KCNK12,ZIC2,ZIC3,KCNT2,ANKS1B,CADM2,GAL3ST3,AP3B2,JPH3" Coexpression Atlas Arv_EB-LF_500 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500 PCBC 3.72E-06 1.90E-02 2.44E-05 2.22E-04 121 499 "SERPINA3,AGT,KCTD16,DPP10,C1QC,MYRF,CALB2,CAMK2A,LGI1,LHX2,IGLON5,COL9A1,AKAP5,IGDCC3,HAPLN1,CSF1R,ATRNL1,NCAN,CYBB,DCT,SNAP91,DPP6,EDIL3,EDN3,ELAVL3,ELAVL4,EN2,LRRC17,EPHA5,FABP7,TMEM132C,ZIC4,FCGR3A,ACTL6B,HPCAL4,C1orf61,NSG2,B3GAT1,TMEM151A,PHYHIPL,GABRA2,CHL1,GAD2,GAP43,DNER,GFAP,GFRA2,FREM1,PCSK1N,GPM6A,CCDC184,STMN2,GRIA2,C1QL4,GRIA4,GUCY1A1,CELF3,WIF1,NXPH2,VSIG4,SCRG1,HPSE2,IGFBPL1,CELF5,C2orf72,IGF1,KIAA1755,LIX1,KCNQ2,C2orf80,MAPT,SCG3,RSPO2,MYL3,TCEAL5,NELL1,NNAT,NPY,NTRK2,OLR1,OXTR,PAX6,PCDH8,PDGFRA,PENK,GDAP1L1,HMGCLL1,PDZRN4,PRRX1,MAGEL2,POU3F2,NKAIN4,PRPH,RELN,PTH1R,PTPRN,PTPRO,RFX4,RGS4,HUNK,LINC00461,TMEM200C,TMEM132D,SLIT1,SLN,SPP1,CLSTN2,SST,MLC1,SYT4,TAC1,TAC3,CNTN2,TF,ZIC1,PLPP4,CRB2,DPYSL5,STMN4,SCG2,SLC17A6" Coexpression Atlas parathyroid gland parathyroid gland Human Protein Atlas 3.82E-06 1.95E-02 2.51E-05 2.28E-04 90 347 "AS3MT,USP35,ALCAM,AMPD3,DDO,PTCH2,RASL11B,CCDC181,ADAM23,CA8,LURAP1,MTMR7,CDH2,CHGA,CHN1,PLEKHB1,CHRNA4,KIAA1549L,CCDC151,COL9A2,NRG2,IGDCC3,TENM4,PYGO1,KATNAL2,FRMPD4,C8orf34,MAGI2,SACS,SPOCK3,SV2A,RCAN1,SEZ6L2,EN2,EYA1,ATP8A1,FGF13,ZMYND15,ATP13A4,IQGAP2,SYT17,NTNG2,GLRB,PCDH11X,TDRKH,GRIK5,GRM7,RNF165,GAREM2,KCNJ3,KCNJ16,STXBP5,PPM1L,MPP2,SAMD5,GPR88,MAPK4,HYDIN,CNNM2,NCR3LG1,ELOVL2,PTN,PTPRD,PTPRG,RET,LGI2,SGSM1,KCNIP3,RYR3,LRFN5,SCG5,ABLIM3,OGDHL,MCF2L2,PLCB1,TMEM178B,ADGRL3,ACSL6,FAM189A1,PCDHB6,PCDHAC2,RELL2,RIMBP2,LRRC24,ANO5,CLEC2L,VLDLR,FMN2,TIGD6,AP3B2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K1 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 3.94E-06 2.01E-02 2.58E-05 2.35E-04 108 435 "ACTN2,METAP1D,ADCY2,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,ZNF599,C1QC,LDLRAD4,REPS2,KCNAB3,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,PTK2B,DLL3,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,GNG4,ADAP1,GRK4,GRIA1,TMEM25,GUCY1B1,TCEAL6,KNDC1,SCIN,ZNF385B,ITGAV,KCNA6,KLHL23,GPR155,MID1,MITF,MOBP,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,STRC,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,DUSP15,MORC4,PRIMA1,MYH14,STK32B,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,SLC1A2,SLC6A9,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,TMOD1,LRRC24,KCNE5,LAMP5,CADM2,LRP8,PCDH15,DNAH10,DPF3,PRRT4" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Lungmap Mouse Lung E16.5 Matrix fibroblast Lungmap CCHMC 4.26E-06 2.17E-02 2.79E-05 2.54E-04 104 416 "NDRG2,AXIN2,ERMN,ADRA1B,ALCAM,SRPX,ABCD2,LTBP4,SMIM29,PPP4R4,DYNLL1,CACNA1D,RUNX1T1,CDO1,MAGED1,ABI3BP,CNRIP1,CP,RBM39,AKAP12,VCAN,BOC,DOCK4,MYADM,ARHGAP24,BRINP1,HEPH,TIAM2,RCAN1,DTNA,EDNRA,PLXNC1,RGS17,PCOLCE2,EML1,LRRC17,RASGRP2,MTSS1L,RASL12,FGFR3,FHL1,GPR153,PNMA2,GAD2,CPLX2,GFRA2,FREM1,GHR,KIRREL3,NR3C1,GSN,GYG1,KCNA2,LAMP2,MAN2A2,MAPT,MEIS1,MYO6,NCAM1,NRCAM,SETD4,PBX1,SERPINE2,PKD1,FXYD1,LRP12,SEPT4,NKAIN4,MAPK7,VPS13C,PXK,PTPRD,PYGM,PID1,FAT4,ARID4A,RGS10,SEC61A2,RAVER2,ROBO1,ROBO2,RYR3,SCN3A,ABLIM3,SLC1A3,PREX2,LIMCH1,PALLD,FGD4,ADAMTS17,TACC1,PDLIM2,PCDHGA6,HIF3A,TNS1,FRRS1L,PLEKHH2,VIPR2,VLDLR,ZBTB16,ADAMTS9,CAMK1G,CERS6,ADAMTS10" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.46E-06 2.27E-02 2.91E-05 2.65E-04 47 150 "NCKAP5,PCDH10,USP37,INSYN2B,ZNF599,LDLRAD4,CH25H,CNR1,PCYT1B,SLC35F1,NCOR1,RIMS2,TOX,PITPNC1,NTM,DLX1,SEMA3D,EFNA3,EPHA5,WAC,UBE2E3,FOXF2,DNER,PPARGC1A,GLRB,TOX3,KIAA1958,MAP4K5,WIF1,VWA2,PAK3,PCDH8,GPR85,OLA1,PLXNB1,FIGN,C12orf49,ROBO1,RPS20,CCDC112,ANKRD6,ZNF365,SLC15A2,KLHL7,RPRM,WNT7A,NETO2" Coexpression Atlas GSM605883_500 "Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 4.63E-06 2.36E-02 3.02E-05 2.75E-04 101 402 "ADRB2,MTUS1,ABCD2,AMPD3,APOC2,APP,CASK,ASPH,ATP1A3,BACH1,ST3GAL5,SCARB1,ZFYVE9,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,CSF3R,CST3,SDC3,CTNND1,CX3CR1,CYBB,MYADM,KIAA0513,LONRF1,DGKG,SIRPA,ZEB2,TIAM2,RCAN1,ABCC5,EBI3,EPS8,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FGR,FLT1,CAMKK2,TPPP3,FYB1,GCNT2,GK,ADAP1,SLC2A6,ATG4C,IRAK3,HP,IFI16,LRRC25,DOCK7,IL6R,ITGAM,ITGAV,L1CAM,LIFR,PIK3AP1,NAT8L,LDLRAD3,MEF2C,NCF2,PFKFB4,CDK14,PLTP,PILRA,DRAM2,PRKAB2,PTPRE,PID1,C1orf54,ARHGEF10L,ACER3,RPS6KA2,LRRK2,RTN1,SEC14L1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,RAP1GAP2,SAMSN1,FGD4,TCF7L2,TF,TGFBR3,TLR4,TNFRSF1B,TPD52,TRPS1,ZBTB16,EVI5,PLD4,NLRP3" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500 facebase_RNAseq_e8.5_FloorPlate_2500 Gudmap RNAseq 4.68E-06 2.39E-02 3.05E-05 2.78E-04 339 1659 "TTYH1,ABCF1,ACHE,ARID1A,SLC12A5,PLEKHH1,UNC5A,KIAA1211,ZNF608,NME5,CEP126,AMPH,PHF12,CNIH2,EPB41L5,APLP1,UPRT,VAT1L,SHTN1,ARHGAP5,ARHGDIG,ARRB2,CADPS,CAPRIN2,PTCH2,ATM,KIF1A,BARD1,BCHE,BID,PROM1,FUBP1,OSGIN2,WASF1,MYRF,CA4,CA12,THSD7A,HAP1,PTBP2,CAMK2A,BRSK2,SHISA7,MTMR7,ARHGEF1,CDK11B,CDC27,CDH2,ZMYM4,LRRFIP1,CCPG1,TBRG4,CACNA2D2,CBARP,NRXN3,PPT2,CLCN3,KIAA1549L,FAM189A2,FAM19A5,C4orf33,QKI,CNTFR,IQCK,COL9A1,SLC4A7,IFFO1,BAG4,IGDCC3,NECTIN3,ZNF385A,SLC35F1,FAM171B,AKAP12,CRMP1,HAPLN1,CLIP3,LRRC3B,FAM169A,CTH,GREB1,CTNND2,KATNAL2,TMEM170A,TOMM20,RUSC2,DDX46,POM121,DLG3,CASP8AP2,DPP6,FAM78B,DUSP9,E2F5,SEZ6L2,EDN1,EFNA3,YAF2,LPAR6,ELAVL2,EML1,PAN3,EMX2,RASGRP2,EPHB1,SRRM1,ERBB4,NCALD,RTN3,CEND1,EXTL2,ADGRV1,CD320,REEP2,WAC,TUBB4A,CEP78,PRMT5,OLFM1,POLR1B,SPSB4,AMOTL2,FHL1,IQCG,FOXM1,FLNC,AFF2,NOP56,SYT3,COQ5,CINP,SMC2,USP21,PRELID3A,DACH2,FUT9,PHYHIPL,HIGD1B,MTHFD2,GART,WASF3,GATM,CSDC2,GGT7,TCERG1,GLDC,DBF4,GLI2,TOX3,KIAA1958,GNAO1,GNG3,PSRC1,GPD2,GPR19,LPAR4,CECR2,STMN2,GRIK2,RNF165,GSTM5,RABL2A,PSIP1,CELF3,TOX2,FRMD5,HSF2,HSP90AA1,SHISAL1,LRRCC1,LRRTM3,SLC35G1,KCNK1,KIF2A,IPO5,KTN1,CAMK2N2,LMO1,LSAMP,MAOB,MAP2,MAP6,MAPT,MAT2A,AQP11,MEST,PPM1L,MSI1,ADAM22,MDGA1,MYCN,MYH7,LINC00672,NAP1L1,NASP,RCOR2,NEFM,CNOT4,NOVA2,NRCAM,CLDN11,PAK3,PDCD2,TMOD2,FAM98B,OLA1,PFKP,PIK3CD,SNX10,RETREG1,PKM,SLC25A23,PRIMPOL,PMP22,FAT3,FSD1,PPP1R1A,NKAIN4,PRKCB,MAPK4,MASP1,RELN,SYTL2,LAMA1,GDPD2,PTCH1,UHRF1BP1,ELOVL2,ZIK1,PTPN13,EML5,CASTOR1,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,PRRT2,ERI2,MORC4,FIGN,RFX3,RGS4,NUDT11,LGI2,SETD5,MYH14,RAVER2,ROBO1,RPL15,KIAA0895L,RIMKLA,HUNK,KCNIP3,YJEFN3,SALL1,MAPK12,LRRTM4,FAM19A1,SOX6,TRIM46,ASRGL1,HSPA4L,SCG5,KIF21A,NTNG1,FHOD3,CCDC92,ANKRD6,ZNF365,PKNOX2,SHANK2,SLC20A2,TET1,PDZD2,SOX2,SOX5,SOX11,BEX1,SPTB,RBM26,PBLD,POGZ,LARP4,LRRC4,NEK4,SEPT3,SYT11,ARC,ANKRD28,MTCL1,WWC1,WSCD1,CUX2,TCF7L2,SIRT1,C18orf54,ITGB3BP,TJP1,HEY2,BEX4,TNFRSF1B,PRMT8,STXBP4,TRPC1,CA14,TST,TMEFF2,CADM1,EIF4ENIF1,AMOT,SLAIN1,USP1,MEAF6,CCDC14,LMF1,XPO1,ZNF23,ZFP41,ZBTB16,ZNF184,DPYSL5,SMARCAD1,EMSY,SHD,SLC38A1,RGMA,STOX2,TUBA1A,SEMA3B,NAV2,WNK3,AMN1,FZD3,SMIM8,PHTF2,AAAS,NETO2,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.69E-06 2.39E-02 3.05E-05 2.78E-04 167 736 "SERPINA3,NDRG2,ADCY5,PLEKHH1,TAOK1,SPARCL1,ANK1,PI16,APC,DDO,BCAS1,ASPA,ATP1A2,ATP2A2,MYOM1,ADAM23,NRP2,GPR146,DST,CACNA2D1,NGB,CAMK2D,CAST,ENTPD2,LRRFIP1,PLEKHB1,AKAP6,ABI3BP,MFSD4A,CP,CLOCK,GDA,OSBPL3,PLCH2,CNTNAP2,CTNND2,DNAJC6,MFAP3L,RABGAP1L,CCDC3,KBTBD11,CHRDL1,DMD,DMPK,CPEB2,DTNA,ABCC9,HIPK3,TMTC1,OPTN,MBNL2,PCOLCE2,RCAN2,NCALD,MRVI1,NRN1,EFEMP1,FGF1,FHL1,CAP2,C2orf88,SORBS1,FUT9,PHYHIPL,DKK3,CHL1,GALNT15,ILDR2,DNER,IGSF5,GCNT2,ADAM28,LYVE1,PRUNE2,GPM6A,TPPP,GSN,BVES,WIF1,HLF,HNMT,IFI16,IL6ST,SLC35G1,KCNA1,KCND3,KCNF1,KCNK1,KCNMA1,LMO1,MAP4,MBNL1,MBP,NFIA,NFIX,NPTX2,HCN1,DDR2,PDE4D,PFKP,ABCB1,CCSER2,PLCL1,JAKMIP1,PLP1,FA2H,PRKAB2,PRKCB,DIRAS2,SYTL2,PTHLH,PTPRB,PTPRZ1,PLEKHB2,RASGRF2,ZDHHC14,TRIM68,RGS4,TTLL7,CLIP1,RYR3,SCN2A,SCN7A,STUM,SH3BGR,SH3GL2,CPEB3,FHOD3,SMTN,LIMS2,SLC14A1,CPEB4,RIMS1,SNAP25,FNBP1,DBNDD2,ATP10B,SYN2,POPDC3,TACC1,SEMA4A,TF,HHIP,SLC44A1,ENHO,NACC2,TIMP4,TLR4,ERCC6L2,TNS1,TPM1,TPM2,RGMB,SYNPO2,PPIL6,UCHL1,RBFOX3,AGMO,ZBTB38,ZBTB16,PLSCR4,RGS7BP,FAM13C,DOCK8,ADAMTSL3,MSRB3,SSPN" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000_k5 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.73E-06 2.41E-02 3.07E-05 2.80E-04 54 181 "TKTL1,LGR5,PLA2G4C,PDE8B,ASPA,INSYN2B,SYNJ1,SCAPER,CALB1,KMT2C,NMT2,CNR1,GREB1,MAGI2,DYNC1I1,DRP2,DTNB,DNAJB6,ATL1,RASGRP1,ELAVL2,ATP8A1,KIAA1109,ATP6V1H,ILDR2,GATM,AIFM3,MAP7D2,GRK4,KIF3A,ZNF385B,KCND2,MYO5A,NEXMIF,GLIPR1L2,SERPINI1,JAKMIP1,PLP1,PPP2R5E,PRCD,FNIP1,TNFRSF19,HSPA4L,CPEB3,SYBU,SYNE2,SLC37A2,ANKRD12,DMXL2,TEX15,TBC1D15,ZNF23,REEP1,PHTF2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_1000 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.92E-06 2.51E-02 3.19E-05 2.91E-04 26 65 "SLC4A4,ADAM23,CACNA2D1,CFL2,CLCN3,DNAJC6,MFAP3L,KBTBD11,CPEB2,EFEMP1,CAP2,PDLIM5,DKK3,IL6ST,KCNMA1,ALDH1L2,DIRAS2,RYR3,ZHX3,FGD4,SYN2,HHIP,SYNPO2,VLDLR,FAM13C,MSRB3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.93E-06 2.51E-02 3.19E-05 2.91E-04 65 231 "EMILIN3,ADD3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,TMEM263,BCHE,CACNA2D1,CANX,PREPL,VCAN,DZIP3,TM9SF4,ZEB2,PDCD6IP,DYRK1A,EDNRB,HIPK3,SEMA3D,EIF4G1,DCTN4,EPHB1,ETV1,DLC1,KIAA1109,SMC2,PDLIM5,CAMKK2,GABRA3,AHCYL1,PCDH17,PCDH11X,RAPGEF4,RASSF8,HAS2,RBPJ,JAK1,LIMS1,CHIC1,MKLN1,MMP16,SAMD5,NFIA,PDE3A,TRA2B,PREX2,CPEB4,SOX5,PEG10,C11orf87,AGTPBP1,FBXW11,TBL1X,NSD1,PUM2,ZFPM2,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,WRN,NETO1" Coexpression Atlas GSM538248_500 "Myeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 4.93E-06 2.52E-02 3.19E-05 2.91E-04 97 383 "PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,CADM3,ADAM23,ST3GAL5,CACNA1E,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,CSF2RA,PDE4DIP,CTNND2,USP6NL,CYBB,DOCK4,HDAC9,MYADM,SIRPA,ELMO1,CDON,DSCAM,PLXNC1,RASA4,PLEKHA1,EPS8,IGSF6,TLR7,SIRPB1,FGR,FYB1,MALT1,HPGDS,RAB30,GPM6B,ADAP1,ZNF496,GSN,FRMD5,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KCNJ16,KIT,ADAM11,MEF2C,AFDN,STK32C,ADAM22,LINC00672,MYO5A,PFKFB3,CDK14,ABCB1,PLTP,RASGEF1B,PRKCB,PTAFR,PTK2,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SCN3A,DOCK10,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,MYCBP2,RGL1,SULF2,ADGRL3,KIAA0930,CYB561A3,SLC44A1,DDHD1,TNS1,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K2 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 5.04E-06 2.57E-02 3.26E-05 2.97E-04 149 644 "ABAT,EMILIN3,HECW2,RTL9,SEMA6A,ANK1,KCNAB2,CACHD1,CDK10,PDXK,IGDCC4,SPTBN4,RASL11B,CACNA1G,GPC2,CACNA2D1,RUNX1T1,CDO1,CRLF1,DIS3L,COL9A2,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,ATRNL1,BOC,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,ABCC9,MBNL2,LRRC17,DENND4A,HSPA12B,DLC1,FDFT1,TESK2,SCARA3,FOXF2,SYT3,ZBED3,TRIM16,NSG1,STAU2,TMEM151A,TVP23A,ZMAT1,TRAF3IP2,ZNF274,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,WIF1,BACH2,SYNPO,AGBL5,IDH3B,IL11RA,ITPKB,JAK2,CREG2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,MBNL1,SRSF12,CD200,N6AMT1,RSPO2,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PDGFRA,PFKFB2,CDK14,FTO,PRRX1,EPB41L4B,TATDN3,CCDC144B,CRLS1,DIRAS2,LRRC49,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,RGS10,ZFHX4,MRAP2,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SMARCC2,IFT122,LIMCH1,PDZRN3,CDK19,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,CRTC1,HIF3A,ASXL3,DAAM2,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,FTSJ1,ADAMTS10,SSPN,KLHDC1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte Top 200 Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte Top 200 LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 5.24E-06 2.67E-02 3.38E-05 3.08E-04 153 665 "ACADM,NDRG2,INTS2,SNX32,SPARCL1,LTBP4,CDC42BPA,MAP4K3,APBB2,APP,CASK,DOCK11,SGCE,ARHGEF25,KRIT1,CCNH,CD81,SEPT7,CDH2,DCLK1,CDO1,UBE2L6,CFL2,CHN1,NRXN1,STOML1,ABCG2,CNN3,ARHGEF6,AKAP7,SUMF2,CNRIP1,PNKD,AKAP12,FEZ2,ARHGEF10,GPSM1,FGFR1OP2,DGKB,DBN1,ARMCX2,RUSC2,FAM107B,DMD,FARSB,ABCC9,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,VPS26C,RCSD1,RASL12,EXTL2,TUBB4A,DLC1,SGIP1,NOP56,SARAF,DKK3,DENND2A,NCKAP1,HIGD1B,HTATSF1,GNAS,FERMT2,GPM6B,PSIP1,GUCY1A2,FAM107A,GUCY1A1,GUCY1B1,MIER3,C5orf24,KCNK3,GATD1,TTYH2,LAMA2,LIMS1,MAP2,MAPT,MAT2A,MEF2C,MEST,MN1,CCDC80,N6AMT1,NEK1,NF1,NME4,PDE3A,ENPP2,PDPK1,PIK3R1,PCDH18,EXOSC10,SEPT4,NKAIN4,PKIA,PRKAR1B,PTK2,PYGM,C1orf54,ZDHHC4,RGS4,ELP2,PRR5L,EMID1,HUNK,PEAR1,DZIP1,PREX2,BTBD3,SMTN,SIRT2,PDZD2,SOX5,SOX11,ZSWIM8,MYCBP2,DBNDD2,ZBTB43,CLSTN2,SSTR2,ST5,INKA2,PJA1,TAF9,PDLIM2,ALG1,MGRN1,TNS2,AKTIP,ACTR6,TP53BP1,TRO,TUBB2A,CADM1,MICAL1,VSNL1,CLDND1,CFAP298,MICU3,TUBA1A,TMEM178A,SMIM8,ADAMTSL3,RNF170,FRMD6" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_500 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.46E-06 2.79E-02 3.52E-05 3.21E-04 107 433 "KDM5D,HECW2,KLHL13,NR0B1,ARHGAP20,CACHD1,PPP4R4,DDX3Y,TMEM108,MYRF,CACNB2,CALB1,CBLN1,CDH10,DCLK1,MAGI1,CLU,CNTFR,AKAP5,ZNF521,HAPLN1,TENM4,MICAL2,ATRNL1,VCAN,PLXNA4,DOCK4,DAPK1,SCRN1,DCT,DNM1,CPEB2,DRP2,EDNRA,SEMA3D,MRO,PLXNC1,EMX2,MTSS1L,F3,FAM198B,FABP7,PTK2B,FLNC,GABRA4,DENND2A,FREM1,CSDC2,GHR,PPARGC1A,GLI2,PCDH11X,GPR37,BVES,GUCY1A1,SHISA6,KCND2,KLHL23,MATN2,MEIS1,MTR,NCAM1,NEFM,NFIA,NME4,PDE1A,PDGFRA,PFKFB3,SERPINI1,PCDH18,PRRX1,RASGEF1B,PTN,TMEM255A,RBBP8,RADX,ROBO1,ROBO2,TMEM206,LGR4,MEG3,HUNK,SOX6,RASA3,ST8SIA1,SLC4A3,PKNOX2,PALLD,SOX5,KDM3A,UHRF1BP1L,SMOC1,ST5,ADGRL3,TEX15,ZFPM2,ACTR6,ASXL3,DAAM2,BEX4,TNNT1,FNDC5,TMEFF2,ZNF711,WNK3,DPF3,ST8SIA2" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_500 kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.76E-06 2.94E-02 3.71E-05 3.38E-04 100 399 "ADORA1,LGR5,TMEM108,BCL7A,PROM1,BMP7,BMPR1B,CACNA1G,CA4,CA12,CACNA2D1,MAP7,LRBA,CHN2,SLIT2,CLU,CRYM,SNCAIP,TENM4,VCAN,KIAA0040,GREB1,SCRN1,GSDME,SV2B,NTM,ARNT2,EMX2,HSD17B14,ERBB4,EYA1,FABP7,ST3GAL6,FGFR1,MAD2L2,SCARA3,SEMA4D,STARD10,IGSF5,FAXC,GCNT2,GFRA1,FREM1,TOX3,KDM2B,ADGRA3,TDRKH,CECR2,FAM107A,KCNJ16,KIF5C,CLEC18A,TM6SF1,MID1,MSI1,MYO6,NCAM1,NME4,NPY,PRTG,ENPP2,PENK,KCTD15,PLXNB1,SDK2,SEPT4,MAPK4,LAMA1,PTN,PTPN13,FAM184A,RAVER2,ROBO1,TMEM100,GLDN,SALL1,SCG5,KIF21A,FERMT1,FHOD3,CNKSR2,PDZD2,SOX11,NUDT10,TMEM150C,TACR1,SATB2,CUX2,TRIM2,PCDHB9,HEY1,TRPS1,CA14,CADM1,VLDLR,PLPP4,SLC38A1,ADAMTS9,FZD3,SPATA13" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 5.82E-06 2.97E-02 3.74E-05 3.41E-04 46 147 "TTYH1,SEPT7,LGI1,CDO1,IGDCC3,NECTIN3,TOX,DCC,ZEB2,EDNRB,EFNB3,EN2,ADGRV1,FAM198B,FABP7,C1orf61,ILDR2,FREM1,RND1,HES5,FGFBP3,MEST,MN1,MSI1,NPTX2,NTRK2,PCDH8,ANLN,PLCL1,PLP1,POU3F2,PTCH1,PTPRO,PTPRZ1,ARID4A,VEPH1,RFX4,LIMCH1,SOX2,SOX3,SULF2,SYNE2,SYT4,TCF12,TMPO,RGMA" Coexpression Atlas GSM791102_500 "Stem Cells, SC.LT34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34-, Bone marrow, avg-3" "Immgen.org, GSE15907" 5.88E-06 3.00E-02 3.78E-05 3.45E-04 93 365 "CPNE2,FMNL2,ZNF608,OSBPL1A,CDC42BPA,ALDH7A1,DST,BTK,SGCE,MAP7,UBE2L6,ADGRG1,B4GALT6,NRXN1,FADS2,ABCG2,MAGED1,ZNF521,GDA,CSF3R,CTNND1,GPRASP1,ARHGAP32,DGKG,DNAJC6,ARRDC4,EBF1,PLXNC1,CALCRL,RRAGB,EYA1,ARMCX1,MED12L,FOXO3,NBEA,GATM,GCNT2,GLUL,GRB10,PRDM5,GSTM5,GUCY1A1,IRAK3,KLF12,HLF,HNMT,HTR2A,ICA1,DOCK7,USP54,KLHL23,KHK,KIT,STMN1,LMO2,LYPLAL1,MEF2C,MEIS1,MYCN,NPR2,OCRL,PBX1,SNX10,PSAT1,PRODH,LRRC49,DEF8,SLC6A15,RNASEL,ZNF532,PLPPR3,CCDC112,PEAR1,ITSN1,PPP1R9A,TET1,CABCOCO1,TROVE2,FGD4,ANKRD28,KLHL4,TEK,TIE1,CBX5,TLR4,TNS1,NPL,STXBP4,SSBP2,VIPR2,VLDLR,ZBTB38,PLSCR4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.89E-06 3.01E-02 3.78E-05 3.45E-04 82 312 "RALGAPA1,EMILIN3,USP31,BEND6,FAM135A,OGT,ANK3,APC,CASK,BMP7,CACNA2D1,CANX,CLIP3,SUSD5,VCAN,HDAC4,TOX,KIF26A,TM9SF4,ELMO1,AK5,ARNT2,GRIN3A,DNM1,EDNRA,EDNRB,HIPK3,SEMA3D,EPB41,SPEG,KIAA1109,CAMSAP1,CELF1,GABRA3,IQGAP2,GFRA1,PCDH17,GHR,PPARGC1A,PCDH11X,KIAA1958,PRRC2B,GRIA2,GUCY1A1,GUCY1B1,KLF12,BACH2,KIF5C,MARK1,CHIC1,PPM1L,MKLN1,NCAM2,NFIA,PDE3A,PDGFRA,PIK3C2A,PRRX1,FAT3,KANSL1,NKAIN4,MAPK8,ZYG11B,REV3L,TNFRSF19,BTBD3,ZHX3,MYCBP2,KIF1B,C11orf87,CLASP2,SMOC1,EPB41L3,RGL1,CAMSAP2,HHIP,ERCC6L2,RBFOX2,RGMB,TRIO,TRPS1,NUP214" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.99E-06 3.06E-02 3.84E-05 3.50E-04 51 169 "PCDH10,SYT13,VAT1L,INSYN2B,DST,RUNX1T1,DCLK1,CDO1,CRLF1,ERC2,TOX,MAGI2,SPOCK3,DLX1,EGFR,EPHA5,EYA1,TMEM132C,FOXF2,SGIP1,DACH2,MEGF10,GABRA4,GABRB1,DNER,GLRB,LPAR4,GRIA2,WIF1,IFI16,RSPO2,MYH3,DDR2,PCDH8,TRHDE,PRRX1,ZFHX4,ROBO1,PRR5L,CSRNP3,SCN3A,ANKRD6,SOX2,SOX11,TROVE2,TAC1,UNC5D,ADGRL3,TBX15,SYNPO2,PCDH20" Coexpression Atlas JC_iEC_2500_K2 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#2 PCBC 6.07E-06 3.09E-02 3.88E-05 3.54E-04 83 317 "ADCY2,GALNT13,TMEM108,HAP1,SYT6,DCLK1,DLGAP1,AKAP5,HS3ST5,CRMP1,CRYBB1,KIF26A,AIF1L,SEZ6,PIPOX,IGSF5,PCDH11X,GNG4,KAT7,LINGO1,LRRTM3,CHST6,ZDHHC22,PRKAR1B,PRKCG,PRODH,PTPRD,PTPRN,PTPRZ1,RASGRF2,ZMAT4,RET,RGS7,RIT2,ROBO1,RORB,LGR4,RYR1,SALL1,SCN8A,SCG5,ITSN1,SH3GL2,SH3GL3,PPM1E,SLC1A6,PREX2,SLC8A2,SLC9A5,SLCO1A2,SMARCA4,SNCB,SNRPN,SOX2,SOX3,NMNAT2,HECW1,SSTR2,RHBDL3,SYN1,SYN2,SYP,SYT1,TAC3,TACR1,TCF7L2,PCDHA6,TIAM1,TNNT1,TP53BP1,IL34,TRPC1,TTPA,TUB,TUBB2A,UCHL1,UGT8,MGAT5B,VGF,VSNL1,KCNK12,SLC30A3,PCDH15" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k2 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.08E-06 3.10E-02 3.88E-05 3.54E-04 22 51 "ATP2B1,CACNA2D1,RABGAP1L,SYNCRIP,PDLIM5,GALC,RAPGEF6,ZHX1,LIMS1,NCOA7,CHIC1,ENPP2,RYR3,SORCS3,FAM126B,ZHX3,NPAS3,WASHC4,ZFP91,ERCC6L2,TRPS1,VLDLR" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_500_k3 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.13E-06 3.12E-02 3.91E-05 3.56E-04 30 81 "C1QTNF3,SLC4A4,CHGB,COL9A1,IPCEF1,ELMO1,EBF1,DLC1,PDLIM5,DKK3,GFRA2,RAB40B,GPM6A,RASSF8,IFI16,MATN2,MSR1,MYH6,PENK,PIK3C2A,PRRX1,PTX3,ABLIM3,EFHD1,ZHX3,HHIP,RGMB,TMEFF2,PCDH20,MSRB3" Coexpression Atlas PCBC_ratio_EB_vs_SC_500 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500 PCBC 6.22E-06 3.17E-02 3.96E-05 3.61E-04 120 499 "SERPINA3,AGT,ASCL1,DACT3,MYRF,CDK5R2,LGI1,NOG,ADGRG1,SLIT2,LHX2,CNTFR,AKAP6,ABI3BP,HAPLN1,CSF3R,DCC,ZEB2,CCDC3,DLX1,EBF1,EDN3,MBNL2,ELAVL3,ELAVL4,ERBB4,NRN1,FAM198B,TMEM132C,ZIC4,ZMYND10,FOXF2,NSG2,TPPP3,PHYHIPL,ILDR2,FREM1,GHR,DCLK2,STMN2,GRIA2,C1QL4,GUCY1A1,ATOH8,CELF3,UBE2QL1,SCRG1,SYNPO,IGF1,KIAA1755,HES5,LIX1,IL6ST,SCRT2,INSM1,C1orf194,LRP1B,MEIS1,MEIS2,SAMD5,CCDC80,RSPO2,MDGA1,MYH6,MYL3,NCAM1,NELL1,NHLH1,NTRK2,DDR2,OLR1,PAX6,PDE1A,PENK,PDZRN4,PRRX1,POU3F2,PRPH,RELN,PTHLH,PTH1R,RFX4,RGS4,ZFHX4,WLS,RXRG,SCN3A,LINC00461,TNFRSF19,PEAR1,SOX6,CCDC92,SLIT1,SNAP25,CABCOCO1,ENKUR,CLSTN2,SST,CNTN2,ZEB1,TF,ZFPM2,HHIP,ASXL3,RIMBP2,TRH,FNDC5,FAM181B,ZIC1,EMX2OS,PLPP4,ZBTB16,STMN4,ADAMTS9,SCG2,SLC17A6,MSRB3,SLC39A12,DPF3,FAM181A" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.25E-06 3.19E-02 3.98E-05 3.63E-04 31 85 "EMILIN3,ADRB2,MYOM1,CACNA2D1,CNTN1,COL9A1,VCAN,PLCXD3,NCALD,CAP2,PDLIM5,DACH2,DKK3,MEGF10,GFRA2,LIMS1,NPTX2,CLDN11,PCDH9,NALCN,PTX3,REV3L,SH3BGR,VWC2,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,SSBP2,MSRB3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_100 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100 FaceBase_RNAseq 6.26E-06 3.20E-02 3.98E-05 3.63E-04 34 97 "USP31,GPRASP2,APOC1,MADD,BARD1,LDLRAD4,CACNA1A,HAP1,CNTFR,CSF2RA,C8orf34,ACOT8,ELAVL4,APC2,FOXG1,TMEM151A,ARPP21,PCDH11X,LOXL3,GRIK2,WIF1,HLF,HPSE2,IGF1,L1CAM,PAX6,RAP1GAP,PRRT2,SCG5,PLCB1,PHF24,LEFTY2,UCHL1,SENP7" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.26E-06 3.20E-02 3.98E-05 3.63E-04 34 97 "PNMA8B,PKP4,BACH1,SRSF11,CHM,COL4A5,RBM39,FGFR1OP2,ZC3H11A,EDNRA,EIF4G1,CALCRL,EMX2,EPB41L2,MEX3B,GABRB1,ILDR2,LPAR4,CHIC1,MMP16,NASP,CNOT4,PDPK1,RNASEL,TMLHE,SLC12A2,SCMH1,ZC3H13,CBX5,R3HDM1,SSBP2,ZNF711,ADAMTS9,GAN" Coexpression Atlas PCBC_DE_fibroblast_1000 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_1000 PCBC 6.39E-06 3.26E-02 4.06E-05 3.70E-04 214 987 "KCNH8,ACHE,ADARB2,ADCY2,ADCY8,GALNT13,ADD2,SORCS1,ERMN,NLGN4X,NR0B1,SEMA6A,PCDH10,UNC79,PDZD4,APOC1,LGR5,SLC7A14,ARSE,KIF1A,ADGRB1,FGF17,BMP7,BTK,CASTOR3,C5,MYRF,CACNA1B,CALB1,MAP7,CBLN1,CBS,CLDN10,CCKBR,USP2,CDH8,CDH10,LGI1,CHGA,LHX2,FAM189A2,IGLON5,COL9A1,COL9A2,COL9A3,GAL3ST1,TCEAL2,TENM4,ATRNL1,NCAN,RIMS4,CNTNAP2,PPP1R16B,PLCXD3,RIMS3,BRINP1,SPOCK3,HS3ST4,CALN1,FAM78B,SEMA3D,EFNA2,ELAVL4,ERBB4,TMEM74,PIPOX,RASL12,ADGRV1,FABP7,FGF13,C1orf61,B3GAT1,TBR1,TVP23A,MEGF10,GABRA1,HRASLS5,GABRA3,GABRA5,GABRB3,GAD1,SALL3,ATP8A2,GATM,GFRA2,FREM1,GNAL,GPM6A,GPM6B,LPAR4,GPR37,TMEM121B,CECR2,GRIA4,GRIK3,GRM2,GRM3,TMEM179,FAM222A,HAS2,C1orf94,IGFBPL1,HP,SHISA6,CELF5,NKD1,PLD5,IGSF1,LIX1,TUBB2B,CDH20,KCND2,KCNF1,CLVS2,KCNJ3,KCNN1,KCNQ2,KIF5C,KIT,FGFBP3,C2orf80,MATK,MATN3,MOBP,SCG3,DDX25,MYT1,TCEAL5,BEX5,RCOR2,NODAL,PCSK2,PRTG,SLC10A4,SERPINE2,SEMA5B,A2ML1,JAKMIP1,PDZRN4,PACSIN1,PPP1R1A,PPP2R2B,PPP2R2C,RASGEF1B,PRKCZ,MAPK7,MAPK10,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,RET,PRIMA1,MRAP2,HUNK,RXRG,SALL1,TMEM200C,SH3BGR,SH3GL2,SH3GL3,SLC1A6,SLC8A2,SLCO1A2,CABCOCO1,SNRPN,SOX3,SOX5,SOX10,SOX15,LHFPL4,MCF2L2,SSTR2,ZFR2,NUDT10,TMEM150C,SYT4,TAC3,KLHL4,FAM189A1,LEFTY2,GALNT17,ENHO,TMOD1,FAM124A,ANKRD24,TNNT1,PIK3R5,SEZ6L,TPD52,TRPM2,CA14,TUBB2A,RPRM,VIPR2,RBFOX3,ETNPPL,KCNK12,ZIC1,ZIC2,ZIC3,ZNF708,KCNT2,FMN2,PLPP4,ANKS1B,CADM2,XKR7,GAL3ST3,FAM198A,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_2500_K4 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.41E-06 3.27E-02 4.06E-05 3.70E-04 151 657 "EMILIN3,ACTN2,ADCY2,SRPX,ARHGAP20,APOC2,CDC14B,CDK10,SPTBN4,ZFYVE28,ARRB2,DACT3,ATP1A3,ADGRB2,BARD1,SEC11C,ZNF599,C1QC,CACNA1G,GPC2,IL33,LDLRAD4,CFAP410,CA12,RUNX1T1,REPS2,KCNAB3,CDO1,CRLF1,VAX2,PCYT1B,COL9A2,ABI3BP,CRYBB1,ANKRD44,CRYM,SNCAIP,CSF1R,MICAL2,DZIP3,FGFR1OP2,C8orf34,FAM107B,CCDC3,DLG2,ABI1,DUSP9,ABCC9,EBF1,EDIL3,RASA4,ELN,LRRC17,EPS8,CEP85L,ETV1,TMEM132C,PTK2B,FCGRT,HPCAL4,ZMYND15,SYT3,TRIM16,ST6GALNAC3,STAU2,TMEM151A,ABLIM2,TVP23A,FYB1,ARPP21,TMEM8B,NTNG2,ZNF276,GRK4,WIF1,RASSF8,HLF,HPSE2,SYNPO,ICA1,IGF1,KNDC1,SCIN,LIX1,IL11RA,ZNF385B,KCNJ5,KIT,VWA5A,GPR155,SRSF12,CPNE9,BCO1,TCEAL5,NELL1,NFE2L2,NPY,CLEC9A,NRGN,DDR2,PDE4D,PDPK1,PLCL1,EXOSC10,PRRX1,NXPH1,PRKAR1B,PTPRB,STRC,ACSS3,RAP1GAP,NWD1,ZCWPW1,ZMAT4,DUSP15,REV3L,ZFHX4,MYH14,LRRK2,DGLUCY,MRAS,SH3GL3,ASAP3,DOCK10,SLC1A2,PREX2,DHX30,SLC6A9,SLC8A1,LIMCH1,ARHGAP26,SAMSN1,PLCB1,UNC5D,ALG1,ADGRL3,SATB2,SYNE1,PHF24,FAM189A1,LEFTY2,TMOD1,AMACR,TRPS1,PMEPA1,CADM2,PCDH15,DNAH10,CERS6,FRMD6,DPF3" Coexpression Atlas GSM605886_500 "Myeloid Cells, Mo.6C-IIint.Bl, CD115+ B220- CD43- Ly6C- MHCIIint, Blood, avg-5" "Immgen.org, GSE15907" 6.46E-06 3.29E-02 4.09E-05 3.73E-04 100 400 "ADRB2,ALCAM,ABCD2,AMPD3,APOC2,APP,CASK,ASPH,ATP1A3,BACH1,ST3GAL5,OSGIN2,SCARB1,ZFYVE9,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,CSF3R,CST3,SDC3,CX3CR1,CYBB,MYADM,KIAA0513,LONRF1,DGKG,SIRPA,ZEB2,TIAM2,RCAN1,EBI3,EPS8,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FGR,FLT1,CAMKK2,TPPP3,FYB1,GCNT2,GGTA1P,GK,ADAP1,SLC2A6,ATG4C,IRAK3,HP,IFI16,LRRC25,DOCK7,IL6R,ITGAM,ITGAV,L1CAM,LIFR,PIK3AP1,LDLRAD3,MEF2C,MSR1,NCF2,PFKFB4,CDK14,PLTP,PILRA,DRAM2,PTPRE,PID1,C1orf54,ARHGEF10L,PRR5L,ACER3,RPS6KA2,LRRK2,RTN1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,SNCA,RAP1GAP2,SAMSN1,FGD4,TCF7L2,TF,TGFBR3,TLR4,TNFRSF1B,TPD52,TRPS1,ZBTB16,EVI5,PLD4,NLRP3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte B_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte B_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 6.55E-06 3.34E-02 4.14E-05 3.77E-04 77 289 "NDRG2,SPARCL1,LTBP4,CDC42BPA,MAP4K3,CD81,CDH2,CDO1,UBE2L6,CHN1,NRXN1,STOML1,ARHGEF6,SUMF2,CNRIP1,PNKD,GPSM1,FGFR1OP2,ARMCX2,RUSC2,FAM107B,DMD,ABCC9,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,EXTL2,TUBB4A,SGIP1,NOP56,NCKAP1,HIGD1B,GNAS,FERMT2,GPM6B,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,NEK1,PCDH18,SEPT4,NKAIN4,PRKAR1B,PYGM,C1orf54,RGS4,PRR5L,EMID1,PEAR1,PREX2,BTBD3,SMTN,PDZD2,ZSWIM8,MYCBP2,DBNDD2,CLSTN2,ST5,PJA1,PDLIM2,TNS2,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte B_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte B_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 6.55E-06 3.34E-02 4.14E-05 3.77E-04 77 289 "NDRG2,SPARCL1,LTBP4,CDC42BPA,MAP4K3,CD81,CDH2,CDO1,UBE2L6,CHN1,NRXN1,STOML1,ARHGEF6,SUMF2,CNRIP1,PNKD,GPSM1,FGFR1OP2,ARMCX2,RUSC2,FAM107B,DMD,ABCC9,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,EXTL2,TUBB4A,SGIP1,NOP56,NCKAP1,HIGD1B,GNAS,FERMT2,GPM6B,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,NEK1,PCDH18,SEPT4,NKAIN4,PRKAR1B,PYGM,C1orf54,RGS4,PRR5L,EMID1,PEAR1,PREX2,BTBD3,SMTN,PDZD2,ZSWIM8,MYCBP2,DBNDD2,CLSTN2,ST5,PJA1,PDLIM2,TNS2,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_250 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_250 FaceBase_ST1 6.64E-06 3.39E-02 4.19E-05 3.82E-04 47 152 "SDE2,FZD9,NR0B1,CPNE5,ASCL1,FGF17,CA4,CCNT1,JAM2,RAB33A,CNTFR,FEZ1,SCRN1,JAKMIP2,PHF20L1,ELAVL3,EN2,FABP7,PHYHIPL,NKX6-2,PRRC2B,MFSD2A,SOX21,UBE2QL1,TOX2,USP51,NKD1,HES5,TUBB2B,MT3,SCG3,PAX6,SLC25A23,POU3F4,ANKHD1,ELOVL2,TNFRSF19,HSPA4L,KIF21A,CCDC88A,SOX2,SYT11,TRH,TRPS1,RPRM,FAM181B,ZBTB16" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0 gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0 Gudmap RNAseq 6.87E-06 3.50E-02 4.32E-05 3.94E-04 268 1278 "SYN3,ABHD6,AS3MT,NCKAP5,ADCY6,AXIN2,SORCS1,PLEKHH1,KIAA1211,PCDH19,NME5,KIAA1324,AK2,CEP126,ZNF687,AMPH,AMT,ANK3,FGD2,CNIH2,EPB41L5,CPNE5,LGR5,CDC14B,PDXK,ARHGDIG,ALDH4A1,ATP1A1,BCL7A,PROM1,BMP7,BMPR1B,WASF1,BTRC,CA12,DDR1,HAP1,SHISA7,MTMR7,CBFA2T2,LRBA,LONRF2,LRWD1,ADGRG1,CBARP,CHN2,B4GALT6,PPT2,KIAA1549L,MYL6B,QKI,CNR1,ZNF385A,SH2B1,IPCEF1,PLXNA4,FAM169A,PLCXD3,CTH,GREB1,CTNND2,NOS1AP,HDAC9,KATNAL2,PHF19,DAPK1,SNAP91,SGSM2,DLG3,TRAPPC9,CDON,DPP6,DTNA,SEMA3D,RBM12,APH1A,KCTD3,PLEKHA1,CERCAM,ENO2,DMTN,ERBB2,EFS,SPEG,EYA1,CD320,F3,REEP2,ZSCAN30,SPSB4,SEMA6C,EVL,SEMA4D,SYT3,C2orf88,POMT1,HVCN1,NRG3,PHYHIPL,GALNT15,GALC,SYT17,FAXC,NFU1,GFER,GGT7,PPARGC1A,RUNDC3A,GLDC,TOX3,KIAA1958,KDM2B,POLL,GNG3,LNX1,B4GALNT4,PLPP7,RFFL,GRIK1,GRIK5,RNF165,MFSD2A,SLC2A6,FAM222A,MUM1,PADI2,FRMD5,ACOT7,LIX1,IBA57,SLC6A17,TUBB2B,SLC35G1,KCNJ16,KCNK3,GATD1,KHK,STMN1,SYTL4,LYPLAL1,MATK,AQP11,SYT9,ADAM11,SAMD5,TAGLN3,MYBPC1,MYCN,LYRM9,FXYD6,RCOR2,KSR2,ZNF827,CDK18,PDE1C,PDE3B,PDE4A,PDE1B,FAM98B,PFKFB4,ZDHHC8,SEMA5B,RETREG1,PKM,KCTD15,EPN1,SLC25A23,PLXNB1,CDIP1,FAT3,POLR2F,FSD1,PPP1R1A,NKAIN4,PRKCZ,GDPD1,LAMA1,SPDL1,PTPN13,EML5,PTPRG,NKAIN1,TMEM231,FAM184A,ROGDI,ZMAT4,FIGN,RFX5,KCTD17,ARHGEF10L,C12orf49,ARMC5,PCMTD2,KIAA0895L,RIMKLA,RPS6KA2,PAQR6,YJEFN3,RTN1,HOGA1,SCN2B,SCN8A,HES6,TNFRSF19,SOX6,ZNF821,SH3BP2,KIF16B,SHMT2,FHOD3,ST6GAL1,WDR37,PEX26,SLC8A1,SHANK2,ABTB1,INAVA,SCN3B,WDTC1,KIF21B,SOX11,LRRC4,NCDN,STAC2,KANK1,FGD4,SYP,WWC1,TBCEL,WSCD1,CUX2,TCF7,AZIN2,CYB561A3,TMEM9,TK2,BEX4,PRMT8,LRRC24,ZMYND8,DCBLD1,HSPBP1,CADM1,UBE2H,UCHL1,SLAIN1,MTCH1,CCDC136,VLDLR,KLC2,ATP6V0E2,SLC26A10,SPHK2,POLR3H,SH3GLB2,MEIS3,INTS3,ZXDA,SHD,SLC38A1,RGMA,CIAPIN1,SEMA3B,NAV2,WIPF2,WNK2,FZD3,SPATA13" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.95E-06 3.55E-02 4.37E-05 3.98E-04 63 224 "FMNL2,KLHL13,NR0B1,CACHD1,PPP4R4,ATP2B3,WASF1,CALB1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,MAGI2,CDON,DRP2,KLHL5,TMEM35A,EMX2,NRN1,ABCA8,IP6K2,GABRA4,PCDH11X,TCEAL6,KCND2,KLHL23,KITLG,SESN3,CCDC80,MTR,MYBPC1,MYO9A,NFIA,PDE1A,CDK14,SERPINI1,PPP3CC,CNTLN,FAT4,ZFHX4,LGR4,HUNK,RASA3,SLC4A3,SCMH1,ATF7IP,SNCA,KDM3A,UHRF1BP1L,ST5,ADGRL3,TCF12,SZT2,DNAH7,ACTR6,DAAM2,KAT6B,TNNT1,FNDC5,PCDH20,LYPD6,DPF3" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k1_1000 kidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.24E-06 3.69E-02 4.55E-05 4.14E-04 100 401 "ABR,RNF157,ZNF608,CEP126,AMPH,SEMA4G,BCL7A,BMP7,CACNB4,LONRF2,CDH2,CNTFR,BTF3L4,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,ECE2,PHF19,GSDME,SNAP91,MTX3,DTNA,ELAVL4,C8orf37,KCNMB2,ERBB2,ETV1,RRAGB,EYA1,SLC9B2,FGFR1,MAD2L2,SCARA3,NOP56,TMEM107,STAU2,IGSF5,FAXC,GFRA1,FREM1,TDRKH,B4GALNT4,CECR2,CNTRL,GRIK4,CACFD1,FAM107A,HAS2,NEGR1,MEST,MSI1,ADAM22,NCAM1,NELL1,NME4,CNTN3,PRTG,SMOX,ANKRD16,FAT3,CEP41,MASP1,MDGA2,RBBP6,TSPY26P,NUDT11,TMEM100,HUNK,ZNF354C,SALL1,FAM19A1,ASRGL1,PPM1E,DZIP1,SLC1A3,SLC4A3,YPEL4,SEPHS1,SLC20A2,GKAP1,CMTR2,NUDT10,ADAMTS17,CAMTA1,CUX2,TRIM2,PCDHB10,PCDHB9,PCDHB7,PCDHB3,TMOD1,CADM1,MKRN3,LAMP5,SLC38A1,SIGLEC10,FZD3,DPF3" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k3_500 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.25E-06 3.70E-02 4.55E-05 4.15E-04 15 28 "BACH1,MYRF,DBN1,GSDME,ELAVL2,LPAR4,TUBB2B,NASP,NNAT,SNRPN,SOX2,RBM26,KLHL4,ZIC3,PCBP4" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_2500_K3 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 7.46E-06 3.81E-02 4.67E-05 4.26E-04 104 421 "ACTN2,ADCY2,ADCY8,SLC24A4,HECW2,KIAA1324,SMIM17,ARHGAP20,APOC2,LGR5,ZFYVE28,PDE8B,ATP1A3,ADGRB2,BARD1,C1QC,LDLRAD4,REPS2,KCNAB3,CDH18,CCPG1,UBE2L6,CLU,VAX2,CRYBB1,CSF1R,SUSD5,PLCH2,TIAM2,DLG2,DRP2,SNX29,TMTC1,RASA4,EPS8,PTK2B,DLL3,ABLIM2,FYB1,GAA,ARPP21,TMEM8B,GHR,LYVE1,GLRB,GNG4,GRK4,GRIA1,TMEM25,GUCY1B1,ICA1,SCIN,IL11RA,ZNF385B,KCNA6,KLHL23,GPR155,MID1,MOBP,CPNE9,MYH3,NEXMIF,NELL1,NPR2,OPCML,PDE4D,PLCL1,TRHDE,PILRA,NXPH1,PRKAR1B,MASP1,ACSS3,RALGDS,ZCWPW1,ZNF493,VEPH1,ZMAT4,PRIMA1,MYH14,LRFN5,MRAS,SGK1,SH3GL2,ASAP3,CCDC92,SLC1A2,SLC6A9,ARHGAP26,IQSEC2,C11orf87,ACSBG1,ZFR2,UNC5D,ADGRL3,TMEM136,FAM189A1,KCNE5,LAMP5,CADM2,LRP8,PCDH15,DPF3,PRRT4" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_500 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500 FaceBase_RNAseq 7.64E-06 3.90E-02 4.78E-05 4.36E-04 118 491 "ERMN,PLEKHH1,PTCHD1,FGD2,EPB41L5,SHTN1,ASCL1,FGF17,BLM,PROM1,CA4,CACNA1B,HAP1,MAP7,LRBA,ADGRG1,SRSF11,CBARP,LHX2,NRXN3,CLCN3,TMEM59L,TJP2,IGDCC3,ABCG1,CRYM,OSBPL3,FAM169A,GREB1,ST18,CHRDL1,DLG3,CDON,DTNA,DUSP9,ELAVL2,ELAVL4,EMX2,EPB41,RRAGB,ADGRV1,EYA1,ACSL4,TUBB3,FOXG1,KHDRBS3,FUT9,PHYHIPL,ILDR2,GAD1,GAD2,SRRM4,STARD10,KIAA1841,GLDC,TOX3,CECR2,PCLO,SOX21,PSIP1,FAM222A,TOX2,IGFBPL1,SHISAL1,HES5,KCNH2,KCNK1,KIT,KTN1,MAOB,AQP11,MBP,IL17D,MSI1,MYCN,NNAT,NRCAM,PAX6,PRTG,NECAB2,PSMD13,ELOVL2,PTPN13,EML5,SUSD4,GAL3ST4,FIGN,RFX4,RAVER2,LGR4,SOX8,TRAPPC13,SALL1,MAPK12,LINC00461,KIF21A,FERMT1,SOX2,SP4,NMNAT2,SMOC1,WWC1,WSCD1,WASHC4,HEY1,NR2E1,TPD52,CA14,CADM1,ZIC2,ZBTB16,DPYSL5,TFIP11,SLC38A1,NAV2,PCBP4,FZD3,SPATA13" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k3 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.72E-06 3.94E-02 4.82E-05 4.40E-04 36 106 "RNF157,SLC12A5,FAM135A,ASTN1,ADAM23,KALRN,MAP4K4,CRMP1,PPP1R16B,ECE2,SPOCK2,BRINP1,SNAP91,USH1C,EFNA3,KCNMB2,SLC43A2,DPYSL4,CHL1,PBX1,PCDH8,EPB41L4B,CEP41,DIRAS2,GAL3ST4,ZMAT4,FIGN,RPS6KA2,HUNK,RYR1,MAPK12,DRAXIN,ZNF334,CLSTN2,ASXL3,TPM2" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_200 DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.80E-06 3.98E-02 4.87E-05 4.44E-04 50 166 "ADD1,PNMA8B,ARHGAP20,LCORL,PKP4,DDX3Y,ATP2B1,BACH1,IL33,VSTM2A,RUNX1T1,CHM,SLIT2,COL4A5,RBM39,ZEB2,ZC3H11A,EDNRA,EIF4G1,EPB41L2,LRRC17,LPAR4,GRM7,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,MYBPC1,NASP,NFIX,PCDH9,NALCN,PIK3R1,FAT3,C1orf54,TMLHE,MEG3,SFPQ,TRA2B,ARX,PRRC2C,KLHL4,CBX5,R3HDM1,NR2C2,SSBP2,FLRT2,ADAMTS9" Coexpression Atlas GSM538271_500 "Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3" "Immgen.org, GSE15907" 8.22E-06 4.19E-02 5.13E-05 4.67E-04 102 412 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,CC2D2A,CEP126,SEMA7A,APP,SHTN1,TMEFF1,ARHGAP5,CAPRIN2,ZBTB10,ATP2B1,N4BP2L1,ADAM23,NRP2,CFLAR,CDH2,LARGE1,UBE2L6,ARHGAP22,ZFYVE9,CLU,FAM189A2,LY86,ANKRD35,SLC4A8,ABCG1,ATRNL1,CST3,PNPLA8,CTNND1,RASSF2,PLPPR4,RABGAP1L,DSCAM,MAMLD1,DNM1L,EFNA2,PLXNC1,RASA4,ENO2,EPB41L2,MTSS1L,DENND4A,CDHR1,EXTL1,MEX3B,ZMYND15,NBEA,NEK6,MTHFD2,RAB30,SLC2A6,GYG1,HSF2,DOCK7,SCIN,INSM1,JAK2,KTN1,TTYH2,VWA5A,ASPRV1,ADAM11,NPR2,PBX1,PFKFB3,CCSER2,PLCL1,SLC22A23,PLEKHB2,ROGDI,RGS12,DGLUCY,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,EPB41L3,ST5,SULF2,STXBP1,ARHGEF9,TMEM150C,ARC,ATP11A,PHF24,ARHGEF12,TJP1,DDHD1,TNFRSF1B,SYNPO2,TRIO,TRPS1,ZBTB38,SPIRE1,WNK1,CERS6" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.42E-06 4.30E-02 5.25E-05 4.78E-04 49 162 "NR0B1,ARHGAP20,DDX3Y,MYRF,CALB1,CBLN1,CDH10,CNTFR,HAPLN1,TENM4,ATRNL1,VCAN,PLXNA4,DOCK4,DCT,DRP2,EDNRA,PLXNC1,EMX2,FLNC,GABRA4,FREM1,GHR,PCDH11X,GPR37,GUCY1A1,GUCY1B1,KCND2,KLHL23,MATN2,MEIS1,CCDC80,NCAM1,NEFM,PDE1A,PDGFRA,PCDH18,PRRX1,PTN,TMEM255A,ROBO2,LGR4,UHRF1BP1L,SMOC1,ADGRL3,KLHL4,ZFPM2,ACTR6,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k1 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.67E-06 4.42E-02 5.39E-05 4.92E-04 46 149 "ADCY5,PI16,APC,ADAM23,CACNA2D1,ENTPD2,CFL2,MFAP3L,RABGAP1L,CHRDL1,CPEB2,ABCC9,HIPK3,CALCRL,MRVI1,NRN1,EFEMP1,DLC1,CAP2,PDLIM5,DKK3,DNER,GCNT2,GSN,KCND3,MBP,NFIA,PIK3C2A,KANSL1,REV3L,TTLL7,SCN7A,RIMS1,ZHX3,MYCBP2,SYN2,TACC1,CAMSAP2,TGFBR3,HHIP,ERCC6L2,TBC1D15,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_1000 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000 PCBC 9.07E-06 4.62E-02 5.63E-05 5.13E-04 214 992 "GPRIN1,ADCY2,ADCY5,ADCY8,ADCYAP1R1,ADD2,PTCHD1,NLGN4X,SPARCL1,PDZD4,ZFYVE28,PLA2G4C,ARSE,MARCH3,ATP1A3,CARMIL3,AZGP1,LDHD,CA12,CALB1,DIRAS1,SYT6,RUNX1T1,CBS,LDB2,SCARB1,DCLK1,CHGA,CHRNA4,RAB3C,RAB33A,FAM189A2,FAM19A5,CNTN1,CRYBB1,ABCG1,CRYM,GALNT9,VCAN,RIMS4,SEC14L5,KIF26A,KCTD8,BRINP1,MAGI2,NTM,RABGAP1L,HS3ST2,CALN1,DOCK2,FAM78B,ST8SIA3,EEF1A2,CACNG7,AASS,LINC00599,RASGRP2,SEZ6,ANKRD13B,PIPOX,HSPA12B,PPP1R1B,OLFM1,HPCAL4,FLT1,CGREF1,CSPG5,MEGF11,MEGF10,GABRA1,HRASLS5,GABRA5,GABRB3,JPH4,MTHFD2,ATP8A2,GCK,ALDH1L1,GNAO1,GNG4,GPM6B,RAPGEF4,GRIK3,GRIN1,ADAMTS8,NR3C1,GSTT2,MFSD2A,LINGO1,WIF1,IRAK3,C1orf94,HRH3,HNF4G,NEGR1,LRRC75A,IGSF1,RIPPLY2,LRRTM3,ITGAM,KCND2,KCNK1,KCNN1,KCNN2,KCNQ2,KHK,KIF5A,CAMK2N2,FGFBP3,C2orf80,PIK3AP1,MATK,MMP17,CPNE9,MT1M,SCG3,MX1,MYCN,FXYD7,ALDH1L2,NODAL,NOS1,NPTX1,NPTX2,HCN1,P2RY1,ZDHHC22,PAH,PDE4B,SLC10A4,CYTL1,GDAP1L1,CAMKV,PIK3CD,TMEM38A,PLCB2,ST8SIA5,JAKMIP1,FXYD1,PLTP,PLXNB3,EPB41L4B,FAT3,POU3F4,PPP2R2B,PPP2R2C,PRODH,PTAFR,PTPRZ1,TMEM145,NKAIN1,SLC25A48,ZMAT4,RET,RIT2,RORB,MRAP2,SGSM1,RIMKLA,RYR1,SCN4B,FERMT1,SHMT2,BCAN,SLA,PREX2,SLC6A11,SEPHS1,SHANK2,TMEM132D,OGDHL,SNCB,SNRPN,TNIK,LHFPL4,HECW1,UNC5B,SSTR1,SEPT3,AJAP1,ACSBG1,NECAB1,RHBDL3,SYN1,ARC,SYN2,POPDC3,TAC3,TACR1,SEMA4A,KLHL4,TMEM151B,ARHGAP9,TEX15,TEK,CHST8,ENHO,TIMP4,RELL2,TLL2,PIK3R5,TPD52,RASD2,TPM3,IL34,TPM4,UGT8,VAV1,VIPR2,ZIC3,SLC30A3,PMEPA1,SHD,NETO1" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_LateralEmin_500_1 e10.5_NeuroEpith_LateralEmin_top-relative-expression-ranked_500_1 FaceBase_ST1 9.30E-06 4.74E-02 5.77E-05 5.26E-04 45 145 "SDE2,FZD9,NR0B1,CPNE5,ASCL1,FGF17,CA4,CCNT1,JAM2,RAB33A,CNTFR,SCRN1,JAKMIP2,PHF20L1,ELAVL3,EN2,FABP7,PHYHIPL,NKX6-2,PRRC2B,MFSD2A,SOX21,UBE2QL1,TOX2,USP51,HES5,TUBB2B,MT3,SCG3,PAX6,SLC25A23,POU3F4,ANKHD1,ELOVL2,TNFRSF19,HSPA4L,KIF21A,CCDC88A,SOX2,SYT11,TRH,TRPS1,RPRM,FAM181B,ZBTB16" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_200 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.37E-06 4.78E-02 5.81E-05 5.29E-04 50 167 "PNMA8B,ARHGAP20,LCORL,DDX3Y,ATP2B1,BACH1,RUNX1T1,CHM,SLIT2,PLAA,COL4A5,RBM39,PUM1,FGFR1OP2,ZEB2,ZC3H11A,EDNRA,EIF4G1,EPB41L2,MEX3B,SMC2,PCDH11X,LPAR4,WIF1,HAS2,CHIC1,MEIS1,MEIS2,MMP16,SAMD5,MYBPC1,NASP,PCDH9,PIK3R1,C1orf54,TMLHE,ROBO2,MEG3,SFPQ,TRA2B,ARX,ZC3H13,RBM26,KLHL4,CBX5,R3HDM1,SSBP2,FLRT2,ADAMTS9,GAN" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.46E-06 4.82E-02 5.85E-05 5.33E-04 26 67 "METAP1D,ADCY8,AMPH,ATP1A2,CACNB4,RBM39,CRYM,DYNC1I1,ELAVL4,TMEM35A,EYA1,FGF1,GABRB3,FAM107A,HAS2,FRMD3,ITIH2,NELL1,FAT3,NXPH1,ROBO2,SALL1,ZFP2,SLC1A3,SLC12A2,TPM2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.46E-06 4.82E-02 5.85E-05 5.33E-04 26 67 "PCDH10,RUNX1T1,ANKRD44,HDAC9,TOX,DRD1,EGFR,EPHA5,ETV1,EYA1,TMEM132C,FOXF2,SGIP1,DACH2,MEGF10,GLRB,WIF1,IFI16,GPR85,PCDH18,TRHDE,PRRX1,ZFHX4,SALL1,CSRNP3,NPAS3" Coexpression Atlas PCBC_ratio_ECTO_vs_SC_500 ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500 PCBC 1.03E-05 5.24E-02 6.35E-05 5.79E-04 119 499 "ABHD6,TKTL1,LGR5,LINC00173,CA4,CAMK2A,P2RX6,CDH18,LGI1,NOG,LHX2,CNTFR,COL9A2,NRG2,SEC31B,HAPLN1,PLCH2,PLCXD3,ST18,BOC,ARHGAP24,DGKG,ZEB2,LYPD1,EDN1,EGR3,EMX2,NCALD,NRN1,CLVS1,ZIC4,PRAM1,DLC1,ATP13A4,TPPP3,PHYHIPL,ILDR2,IP6K3,GPR162,ADAM28,DIPK1C,FAM107A,GUCY1B1,CELF3,UBE2QL1,HAPLN2,ZNF491,HES5,LIX1,INSM1,ZNF385B,ITPKB,KCNA1,OLFM3,SYTL4,CLEC18A,MAP2,MAP6,MEIS1,MEIS2,SAMD5,CCDC80,BCO1,TAGLN3,MDGA1,RTL5,NHLH1,NPY,KCNK10,CNTN3,PAX6,PRTG,PDE1C,ENPP2,HMGCLL1,ASPDH,SDK2,POU3F2,VSTM2L,RELN,FEZF2,RFX4,RLBP1,ZFHX4,KLHDC8A,EMID1,MELTF-AS1,WLS,FAM182A,SLC30A10,PEAR1,ARX,CCDC92,EFHD1,DMRTC1,SOX5,CLSTN2,COLGALT2,STOX1,SMOC1,SSPO,VWA3A,ZEB1,AZIN2,NR2E1,RIMBP2,TRH,FNDC5,ZIC1,EMX2OS,PLPP4,CRB2,MKRN3,ZBTB16,DPYSL5,STMN4,ADAMTS9,DOCK8,FAM182B" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 1.04E-05 5.30E-02 6.39E-05 5.83E-04 116 484 "SLC25A25,NDRG2,ADCY2,CCDC85A,OSBPL8,ARHGAP20,LTBP4,GPRASP2,ANK1,CDK10,DACT3,ADGRB2,ZNF599,BMPR1B,C1QC,CBLN1,LRBA,REPS2,CDO1,CRLF1,LHX2,HOMER3,COL9A1,SLC4A7,IGDCC3,CREB5,HAPLN1,CRYM,CSF1R,FEZ1,GREB1,TOX,CCDC3,DLX1,DUSP9,SEMA3D,EGFR,ELN,EMX2,LRRC17,EPHA5,ADGRV1,FCGRT,FGF11,DPYSL4,FYB1,PCDH17,PPARGC1A,ZNF276,GLDC,PCDH11X,MAP7D2,CECR2,GRIK2,NR3C1,GSN,KLF12,SYNPO,IL11RA,KCNH2,MEIS1,MEIS2,SRSF12,KITLG,MITF,CD200,CCDC80,MSI1,RSPO2,MYCN,NCAM2,NELL2,NFIA,NFIX,NNAT,CLEC9A,CNTN3,PAX6,PCDH9,PRTG,PGAM2,PKM,PLCL1,NECAB2,POLR2F,POU3F4,IRX1,PRODH,ZMAT4,FIGN,SOX8,ATXN1,NTNG1,LIMCH1,SOX11,ZSWIM8,ACSBG1,ZFR2,ADGRL3,WASHC4,PHF24,FAM189A1,CA14,HSPBP1,TSPAN11,CLIP2,ZIC3,FMN2,ZBTB16,LAMP5,PMEPA1,ZXDA,ADAMTS9,PCDH15,PCBP4,SENP7" Coexpression Atlas PCBC_ratio_SC_vs_MESO-5_100 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_100 PCBC 1.04E-05 5.30E-02 6.39E-05 5.83E-04 34 99 "VAT1L,ATP1A3,SYT6,DCLK1,CHGA,CABP1,HS3ST5,PHYHIP,LINC00599,ANKRD13B,PIPOX,CEND1,DNER,GRIA4,C1orf94,HRH3,FGFBP3,CPNE9,FXYD7,NOVA2,ZDHHC22,CAMKV,GDPD2,RYR1,SCN4B,PPM1E,SOX2,RHBDL3,ARC,SYP,TMEM151B,FBXL16,VGF,VSNL1" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.04E-05 5.30E-02 6.39E-05 5.83E-04 34 99 "ABAT,FMNL2,KLHL13,NR0B1,ATP2B3,CACNB2,CALB1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,GABRA4,PCDH11X,KLHL23,MATN2,KITLG,CCDC80,MYO9A,NFIA,ZFHX4,TMEM206,LGR4,SLC4A3,KDM3A,UHRF1BP1L,SMOC1,ST5,ADGRL3,ZFPM2,ACTR6,TNNT1,FNDC5" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K2 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.04E-05 5.31E-02 6.39E-05 5.83E-04 79 302 "ERMN,ALCAM,CACHD1,TMEM108,CA4,CBLN1,INA,CLCN3,LRRC3B,FAM169A,HDAC9,MYADM,ARHGAP24,WDR20,CHRDL1,ST8SIA3,PLEKHA1,SEZ6,PIPOX,CEND1,REEP2,TUBB4A,FGF11,SYT3,JPH4,SALL3,GFRA2,CSDC2,GPD2,LPAR4,CECR2,LINGO1,HMGCL,TCEAL6,HSP90AA1,CDH20,KHK,IPO5,AQP11,MATN2,CD200,CCDC80,NAP1L1,IGSF11,PRTG,PDE1A,PENK,SNX10,ZFYVE21,PKM,FTO,MAGEL2,NKAIN4,PTPN13,TSPY26P,FIGN,STK32B,EMID1,FOXRED2,SALL1,MAPK12,NTNG1,SNRPN,PALLD,PDZRN3,BEX1,PBLD,AJAP1,ADAMTS17,MTCL1,ROBO3,WASHC4,BEX4,FLRT1,ZIC2,ZBTB16,CA10,SLC38A1,PIANP" Coexpression Atlas JC_iEC_2500_K3 JC_iEC_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 1.10E-05 5.59E-02 6.72E-05 6.13E-04 81 312 "EMILIN3,FAM43B,PI16,CADPS,AZGP1,CACNA1E,LONRF2,JAM2,EBF1,KCNMB2,FGF12,GGT5,GNAO1,MAEL,KCND3,CTNNA3,MYBPC1,NCAM1,NTRK2,PDE4A,PMP22,MAPK4,PROX1,MASP1,PSD,PTH1R,PTN,PTPRN2,PTPRO,PYGM,RAB3A,RAB3IL1,RFX2,RFX4,RNASE1,RTN1,RXRG,S100B,ATXN2,SCN2B,SCN4B,SCN7A,SH3BGR,ST8SIA1,SLC1A2,SLC1A3,SLC4A3,SLC1A7,SMTN,LIMS2,SLC6A1,SLC8A1,SLC11A1,SLC12A4,SLN,SMARCD3,PALLD,PDZRN3,PDZD2,SOX10,ST5,STXBP1,ABCC8,SYT4,CNTN2,VWC2,TF,TGFBR3,THBS4,THRA,TIMP4,TLL2,TMOD1,TNFRSF1B,TNS1,TPM1,TPM2,SYNPO2,FNDC5,TSC2,VIPR2" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.12E-05 5.71E-02 6.86E-05 6.26E-04 77 293 "ACTN1,NDRG2,ADCY5,ADORA1,KLHL13,LRRC7,SPARCL1,ALDH7A1,MYOM1,ARHGEF7,CACNB2,DCLK1,LGI1,NDST3,CABP1,C2CD2,AKAP12,VCAN,RIPOR2,NTM,CCDC3,DMD,DMPK,EDIL3,EDNRA,HEYL,CERCAM,NCALD,ETV1,ABCA8,TUBB4A,FHL1,CAP2,CPLX2,IGSF5,TOX3,GP1BB,ADAMTS8,HPSE2,HSPA1L,PLD5,SLC6A17,LRRTM3,LMO1,MEF2C,CTNNA3,MYH3,NTRK3,PCSK2,FXYD1,PURG,FAT3,MAPK10,RELN,SYTL2,LAMA1,TMEM255A,FIGN,RERGL,SALL1,SH3BGR,PPM1E,NTNG1,SLC4A3,SLC6A9,ELOVL4,NUDT10,ADAMTS17,CUX2,HIF3A,HEY2,TPM2,TRPC3,UCHL1,ADAMTS9,KCNAB1,RGS7BP" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_200 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.14E-05 5.80E-02 6.96E-05 6.34E-04 52 177 "HECW2,NR0B1,AMH,SEMA7A,GAS7,SHTN1,LGR5,PPP4R4,ARHGDIG,CADPS,ATP2B3,CACNA2D2,ADGRG1,CLU,CLTB,VCAN,SCRN1,ELMO1,DTNA,MRO,PLXNC1,CERCAM,EPS8,ERBB4,PTK2B,FGF13,SEMA6C,GATM,PPARGC1A,GPM6B,GPR37,KCNH1,KLHL23,KITLG,NELL1,PAK3,SERPINE2,RASGEF1B,ROBO1,TMEM206,RPS6KA2,MRAS,DOCK10,ST6GAL1,EFHD1,TNIK,SPP1,SMOC1,TACC1,SGK3,ADAMTS9,WNK3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte C_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte C_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.18E-05 6.03E-02 7.23E-05 6.59E-04 59 209 "SPARCL1,LTBP4,CDC42BPA,MAP4K3,ARHGEF25,KRIT1,CD81,CDH2,CHN1,NRXN1,CNN3,ARHGEF6,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RCSD1,RASL12,SGIP1,NCKAP1,HIGD1B,GNAS,FERMT2,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,PTK2,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,CLSTN2,SSTR2,AKTIP,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte C_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte C_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 1.18E-05 6.03E-02 7.23E-05 6.59E-04 59 209 "SPARCL1,LTBP4,CDC42BPA,MAP4K3,ARHGEF25,KRIT1,CD81,CDH2,CHN1,NRXN1,CNN3,ARHGEF6,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RCSD1,RASL12,SGIP1,NCKAP1,HIGD1B,GNAS,FERMT2,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,PTK2,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,CLSTN2,SSTR2,AKTIP,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.23E-05 6.28E-02 7.51E-05 6.85E-04 55 191 "KLHL32,GRAMD1B,SORCS2,SPARCL1,ALCAM,ARHGAP20,LTBP4,GPAM,CACNA2D1,ISPD,CBLN1,LDB2,HAPLN1,MICAL2,VCAN,PLCXD3,RIPOR2,ARMCX2,ZEB2,EDNRA,HEYL,EGFR,LRRC17,EYA1,DLC1,GFRA2,GLI2,GPM6A,GRIA4,PRDM5,KLF12,HPSE2,KCND3,LAMA2,MEF2C,PCDH9,PLTP,FAT3,SH3KBP1,LRRN3,PTCH1,TMEM255A,ROBO2,ARMH4,SMTN,SORCS3,PDZD2,ZNF423,SULF2,ARHGEF9,ZEB1,TGFBR3,HHIP,VSNL1,STOX2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte D_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte D_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.27E-05 6.48E-02 7.74E-05 7.05E-04 82 318 "ACADM,SPARCL1,CDC42BPA,MAP4K3,CASK,SGCE,CD81,CDH2,DCLK1,CFL2,CHN1,NRXN1,ARHGEF6,SUMF2,AKAP12,ARHGEF10,DGKB,DBN1,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,VPS26C,RCSD1,RASL12,DLC1,SGIP1,HIGD1B,HTATSF1,GNAS,FERMT2,GUCY1A1,GUCY1B1,C5orf24,KCNK3,TTYH2,LAMA2,LIMS1,MEF2C,MEST,MN1,CCDC80,NF1,PDPK1,PIK3R1,PCDH18,EXOSC10,SEPT4,NKAIN4,PKIA,C1orf54,ZDHHC4,RGS4,PRR5L,EMID1,PEAR1,DZIP1,BTBD3,SMTN,SIRT2,PDZD2,MYCBP2,DBNDD2,CLSTN2,ALG1,ACTR6,TP53BP1,TRO,CADM1,CLDND1,CFAP298,MICU3,TUBA1A,ADAMTSL3,RNF170,FRMD6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte D_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte D_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 1.27E-05 6.48E-02 7.74E-05 7.05E-04 82 318 "ACADM,SPARCL1,CDC42BPA,MAP4K3,CASK,SGCE,CD81,CDH2,DCLK1,CFL2,CHN1,NRXN1,ARHGEF6,SUMF2,AKAP12,ARHGEF10,DGKB,DBN1,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,VPS26C,RCSD1,RASL12,DLC1,SGIP1,HIGD1B,HTATSF1,GNAS,FERMT2,GUCY1A1,GUCY1B1,C5orf24,KCNK3,TTYH2,LAMA2,LIMS1,MEF2C,MEST,MN1,CCDC80,NF1,PDPK1,PIK3R1,PCDH18,EXOSC10,SEPT4,NKAIN4,PKIA,C1orf54,ZDHHC4,RGS4,PRR5L,EMID1,PEAR1,DZIP1,BTBD3,SMTN,SIRT2,PDZD2,MYCBP2,DBNDD2,CLSTN2,ALG1,ACTR6,TP53BP1,TRO,CADM1,CLDND1,CFAP298,MICU3,TUBA1A,ADAMTSL3,RNF170,FRMD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_100_k3 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.27E-05 6.50E-02 7.74E-05 7.06E-04 15 29 "USP31,DPP10,CACNA1B,CDH10,PLCXD3,GRIN3A,CALN1,GFRA1,GFRA2,KIF5C,RSPO2,NDP,CLDN11,PRPH,CUX2" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 gudmap_RNAseq_p2_CD2APMEISWT_2500_K4 Gudmap RNAseq 1.28E-05 6.54E-02 7.79E-05 7.10E-04 185 843 "CPNE2,ABAT,ACHE,NDRG2,ADCY6,ADD2,ADORA1,RNF150,C1QTNF1,BCAR3,TRMT9B,AMPD3,PPFIA2,BCAS1,APP,ARRB1,PDE8B,RASL11B,MYOM1,NRP2,GPR146,CACNA2D1,DLGAP1,UBE2L6,NRXN3,IGLON5,ARHGEF6,CP,AATK,FEZ2,MICAL2,CST3,SDC3,ACY3,DGKB,ZNF804A,ZEB2,SV2A,SGSM2,NR1D2,ABCC9,EBF1,EDN1,HEYL,FRY,OPTN,RCAN2,LRRC17,RASGRP2,SPEG,RCSD1,TLR7,RASL12,MRVI1,ST3GAL6,CHST15,FCGRT,FGF1,FHL1,ZMYND15,SPECC1,NPTN,GPR153,TPPP3,HIGD1B,TUBA8,GDF9,GGT7,GGT5,LOXL3,FERMT2,CCDC184,STON1,NR3C1,GRM7,GSN,GSTM5,GSTT2,GUCY1A2,GUCY1A1,GUCY1B1,SLC2A6,ATOH8,GYG1,FRMD3,HLF,SYNPO,IFI16,IL6R,IL6ST,IL11RA,INPP5B,ITGA7,KCND3,KCNJ5,KCNK3,TTYH2,GPR155,MAP6,MAPT,MARK1,SHC3,MITF,MMP17,CCDC80,NRBP2,MX1,RTL5,NCF2,NRGN,NTRK2,P2RX7,PDE1A,PDE3A,PDGFRA,CDK14,ABCB1,SERPINE2,SERPINI1,PIK3CD,PIK3R1,PLCB2,PLCL1,PLEC,FXYD1,PCDH18,PLTP,SEPT4,PPARA,PRKAB2,PKIA,PTH1R,PTN,PTPN13,PYGM,PLEKHB2,FAM184A,ZDHHC14,ZMAT4,PRRT2,RGS4,ARHGEF10L,ROM1,EMID1,PAQR6,WLS,PRCD,PEAR1,DOCK10,PREX2,SLC8A1,SLC12A2,CPEB4,CABCOCO1,ZCCHC24,UNC5B,DBNDD2,ITPRID2,NKAIN2,RGL1,SYP,PDLIM2,TMEM136,ARHGEF12,TNS2,GPRIN3,TF,TGFBR3,GALNT17,TLR4,DAAM2,TNFRSF1B,TNS1,IL34,TRPC1,TMEFF2,PLEKHH2,ZBTB38,SH3GLB2,RGMA,FAM13C,DOCK8,MSRB3,SSPN,CPNE4" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k2 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.29E-05 6.57E-02 7.81E-05 7.12E-04 22 53 "DPP10,RUNX1T1,CDH10,FAM171B,JAKMIP2,CALN1,EGFR,TMEM132C,FOXF2,SGIP1,DACH2,GRIA2,GRM3,RSPO2,NDP,NEFM,CLDN11,TRHDE,ZFHX4,SALL1,SCN3A,PCDHB7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F-2X DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-2fold-vs-F_top305_305 Gudmap Mouse MOE430.2 1.38E-05 7.02E-02 8.33E-05 7.59E-04 71 266 "KDM5D,RNF157,USP31,DDX3Y,MYOM2,CDC27,DCLK1,ZNF445,COL9A1,ABI3BP,RBM39,OSBPL3,APPL1,PUM1,ZEB2,ALKBH8,EBF1,RBM12,EIF5,EPHA5,FKTN,MEX3B,OGA,RAPGEF6,DNER,PCDH11X,RAB40B,GPD2,LPAR4,GRM7,MAP4K5,RASSF8,IL6ST,PAXBP1,MEIS2,MMP16,MYH3,MYH7,NAP1L3,NFIA,PAK3,PCDH8,PIK3R1,KANSL1,MAPK8,GRAMD1C,PTPRG,RGS4,SEC61A2,PBRM1,CLIP1,FNIP1,TRA2B,KIF21A,ITSN1,SEPHS1,SLC14A1,KIF1B,NPAS3,TCF4,WASHC4,AP4E1,HHIP,ZFP91,RGMB,TRPS1,SSBP2,TTC3,PHTF2,ZDHHC20,SOCS4" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.38E-05 7.02E-02 8.33E-05 7.59E-04 71 266 "FMNL2,KLHL13,NR0B1,KCNT1,CACHD1,PPP4R4,NUMB,ATP2B3,WASF1,CALB1,SLC16A4,DCLK1,MAGI1,CHRM4,PLXNA4,NOS1AP,DOCK4,DAPK1,DRP2,RASGRP1,TMEM35A,EMX2,EPB41L1,NRN1,JKAMP,GABRA4,GABRB1,GALC,GART,GLUL,PCDH11X,PACSIN2,INPP1,KCND2,KLHL23,MAOB,KITLG,AFF1,MYBPC1,MYO9A,SLC11A2,NUCB2,SERPINI1,PIK3C2A,PPP3CC,GDPD1,PTPRG,ZFHX4,LGR4,TNFRSF19,STUM,RASA3,FRMPD1,SLC4A3,SNCA,KDM3A,UHRF1BP1L,ARHGAP26,LRRC4,ADGRL3,SZT2,DOCK9,DNAH7,ACTR6,TNNT1,FNDC5,VAV2,PCDH20,ZNF23,ELFN1,DPF3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_500 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.38E-05 7.06E-02 8.37E-05 7.63E-04 20 46 "REPS2,AKAP5,PLXNA4,NRN1,AFF2,GABRA4,PCDH11X,IGF1,LRRTM3,KCND2,MAP2,MATN2,NEXMIF,NFIA,PDE1A,PCDH18,MEG3,ADGRL3,ZFPM2,TNNT1" Coexpression Atlas ratio_SC_vs_DE_500_K2 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 1.39E-05 7.07E-02 8.37E-05 7.63E-04 28 76 "PLA2G4C,ATP1A2,ATP1A3,AZGP1,LDHD,CA4,CABP1,SLC45A1,CPLX2,ALDH1L1,CCDC184,FRMD3,INSYN1,ITGAM,SLCO1C1,ST8SIA5,FXYD1,SEPT4,PTPRN2,PYGM,SUSD4,ARHGEF10L,SCN4B,ABCC8,SYT5,TNFRSF1B,LGI4,SLC30A3" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.39E-05 7.09E-02 8.37E-05 7.63E-04 32 92 "SYN3,CSMD3,CACNA1B,CACNA1E,NRXN3,DGKB,MED12,ABCC9,EBF1,DENND4A,KIAA1109,FGF14,NOP56,GABBR1,RAB30,GRIA1,PTPRT,LSAMP,RSPO2,NELL1,NTRK3,PDE3A,CNTNAP3,SCN2A,SCN7A,FAM19A1,SLC8A1,UNC80,THSD1,ASTN2,TNR,ST7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.39E-05 7.09E-02 8.37E-05 7.63E-04 32 92 "PCDH10,INSYN2B,DST,DCLK1,TOX,SPOCK3,EPHA5,EYA1,TMEM132C,SCML2,FOXF2,DACH2,MEGF10,DNER,GLRB,LPAR4,WIF1,IFI16,RSPO2,MYH3,PCDH8,TRHDE,PRRX1,ZFHX4,CSRNP3,SOX2,TAC1,UNC5D,ADGRL3,TBX15,SYNPO2,SOCS4" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K5 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.42E-05 7.26E-02 8.57E-05 7.81E-04 57 201 "ADCY8,ERMN,ALCAM,VAT1L,TTLL9,CA4,THSD7A,MAP7,CBLN1,INA,LRRC3B,FAM169A,GREB1,HDAC9,MYADM,ARHGAP24,WDR20,ST8SIA3,LPAR6,CERCAM,PIPOX,CEND1,FGF11,JPH4,CSDC2,HMGCL,TCEAL6,CDH20,KHK,MATN2,CD200,CCDC80,ADAM22,PDE1A,PENK,NLGN3,ZFYVE21,PPP3CC,NKAIN4,CCDC40,TSPY26P,FIGN,STK32B,EMID1,NTNG1,PALLD,PDZRN3,PBLD,ADAMTS17,WASHC4,FLRT1,RBFOX3,PORCN,ZBTB16,CA10,SHD,PIANP" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.43E-05 7.28E-02 8.58E-05 7.82E-04 47 156 "NDRG2,ALCAM,ARHGAP20,LTBP4,CACNA1G,CACNA2D1,RUNX1T1,ARHGEF25,CBLN1,LGI1,SLIT2,SNCAIP,MICAL2,VCAN,RIPOR2,ARHGAP24,ARMCX2,ZEB2,EDNRA,HEYL,EGFR,LRRC17,DLC1,GFRA2,FREM1,GLI2,GRIA4,GUCY1A1,GUCY1B1,KLF12,HPSE2,LAMA2,PCDH9,PDGFRA,FXYD1,PLTP,PMP22,FAT3,SH3KBP1,LRRN3,LAMA1,ROBO2,NTNG1,SORCS3,SULF2,HHIP,STOX2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.46E-05 7.45E-02 8.76E-05 7.99E-04 49 165 "EMILIN3,DPP10,NRP2,DST,RUNX1T1,CDH10,FAM171B,JAKMIP2,DNM1,CALN1,EGFR,TMEM132C,CAP2,FOXF2,SGIP1,DACH2,IQGAP2,GFRA1,GRIA2,GRM3,KLF12,RSPO2,MYH3,MYH7,NDP,NEFM,NFIA,CLDN11,PDE3A,TRHDE,PRRX1,FAT3,KANSL1,REV3L,ZFHX4,SALL1,SCN3A,SLC15A2,SOX2,SMOC1,EPB41L3,CAMSAP2,PCDHB7,HHIP,ERCC6L2,RBFOX2,RGMB,SYNPO2,NUP214" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500 DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.52E-05 7.77E-02 9.13E-05 8.32E-04 95 383 "TKTL1,ADD1,PNMA8B,NR0B1,TAOK1,LCORL,LGR5,MADD,DDX3Y,INSYN2B,BACH1,CALB1,CHM,PLAA,NMT2,CNR1,RBM39,FAM169A,DZIP3,DOCK4,FGFR1OP2,GSDME,SACS,CPEB2,RASGRP1,EIF4G1,ELAVL2,EMX2,EPB41L2,NRN1,SCML2,MEX3B,SMC2,PHYHIPL,GABRA4,GABRB1,ILDR2,GATM,MAP7D2,TDRKH,LPAR4,NR3C1,MAEL,KCND2,CHIC1,KITLG,MYO5A,NEXMIF,NASP,CNOT4,GPR137C,PDPK1,SERPINI1,PLP1,C19orf57,EML5,TMLHE,ACER3,MEG3,PRCD,FNIP1,TRA2B,ARX,CPEB3,SYBU,SCMH1,CPEB4,ZKSCAN3,ZNF667,SOX2,ZC3H13,RBM26,LARP4,SYNE2,SYN2,ANKRD12,KLHL4,DMXL2,AHCYL2,TEX15,SIRT1,CBX5,ACTR6,R3HDM1,NR2C2,TSC1,SSBP2,UGT8,VSNL1,ZIC3,ZNF711,ADAMTS9,SNX27,RSPRY1,GAN" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500 FaceBase_RNAseq 1.54E-05 7.83E-02 9.19E-05 8.38E-04 117 493 "ABCF1,ACTN2,KDM5D,PCDH19,ANK1,MAGEE2,APOC2,CDK10,ARRB2,DACT3,ASTN1,BBS2,MPDZ,ZNF599,PROM1,CA12,DIRAS1,PTBP2,CDK11B,CRLF1,DIS3L,COG1,NIPBL,PCYT1B,SLC4A8,IGDCC3,CRYM,KIAA0586,JAKMIP2,CDON,DUSP9,ABCC9,KLHL5,EMX2,EPB41,ETV1,NSRP1,WAC,TMEM132C,ACSL4,FDFT1,FGF12,HPCAL4,SMC2,ST6GALNAC3,FYB1,C15orf41,ZNF276,TXNL4A,COPS8,CECR2,PCLO,CIT,GSN,MFSD2A,HPSE2,SYNPO,IGF1,LIX1,IL11RA,KIF5C,LAMA2,LSS,GPR155,MBNL1,SRSF12,MID1,BCO1,RSPO2,NASP,NFIX,NNAT,CLEC9A,OPA1,PCSK5,PDE3A,PILRA,DIRAS2,ELOVL2,STRC,ARID4A,ZYG11B,REV3L,KIF7,ZFHX4,TMEM100,SOX8,CLIP1,LRRTM4,CASC3,KIF21A,DOCK10,NTNG1,PREX2,LIMCH1,SPATA7,BDP1,SOX11,C11orf87,SYNE2,TAF9,WASHC4,ARHGEF12,TIAM1,ASXL3,BHLHB9,TMOD1,AMACR,TRPS1,CA14,TTPA,ZKSCAN5,USP1,LAMP5,PMEPA1,HNRNPA3,SENP7" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k5 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.56E-05 7.96E-02 9.34E-05 8.51E-04 56 197 "NDRG2,ADD3,SRPX,ARHGAP20,PCDH10,PTCH2,ATP1A2,ATP2B1,ADGRB3,IL33,VSTM2A,LDB2,DCLK1,NRXN3,COL4A5,CSF1R,PLCXD3,CX3CR1,RIPOR2,CDON,ABCC9,EDNRA,SEMA3D,TMEM132C,FCGRT,FGF1,SEMA6C,GABRB1,GAD1,TNRC6A,GLUL,HTATSF1,PARD3B,GRM7,GSN,RASSF8,KLF12,KCND3,MATN2,NFIA,PCSK5,PENK,NALCN,PIK3R1,FAT3,PTN,C1orf54,LGI2,MRAP2,MEG3,ATXN1,CXXC4,WASHC4,PCDHB9,HIF3A,VLDLR" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k5_1000 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.57E-05 8.00E-02 9.37E-05 8.54E-04 64 234 "SLITRK1,INTS2,TAOK1,LCORL,INSYN2B,RNF182,CALB1,SOCS6,CHM,PLAA,NMT2,CNR1,AKAP5,RBM39,TENM4,DZIP3,GREB1,DOCK4,G3BP2,DRP2,ELAVL2,CALCRL,EMX2,FAM198B,ATP8A1,KIAA1109,GABRA4,ILDR2,TUBGCP4,KIF3A,KCND2,KITLG,NEXMIF,CNOT4,PDE1A,PDPK1,SERPINI1,JAKMIP1,PPP2R5E,PTPRG,TMLHE,PCMTD2,SATB1,FNIP1,STUM,SYBU,SLC12A2,CPEB4,LARP4,SYNE2,SLC37A2,ANKRD12,DMXL2,SIRT1,ACTR6,TSC1,TBC1D15,RICTOR,ZNF711,ZNF23,TRIM9,EMX2OS,REEP1,ADAMTS9" Coexpression Atlas GSM605836_500 "Myeloid Cells, DC.8-4-11b-.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.58E-05 8.04E-02 9.41E-05 8.57E-04 102 418 "CPNE2,ACTN1,FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,APP,SHTN1,CASK,ARHGAP5,CAPRIN2,ZBTB10,ATP2B1,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,CD81,LARGE1,UBE2L6,ARHGAP22,CLU,STOML1,LY86,SLC4A8,CDC42BPB,OSBPL3,ATRNL1,CST3,SDC3,CYBB,MYADM,RASSF2,PLPPR4,RABGAP1L,ARRDC4,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,EXTL1,FDFT1,ZMYND15,NEK6,MTHFD2,RAB30,ADAP1,SLC2A6,GYG1,HMGCR,HSF2,IRF8,DOCK7,SCIN,INSM1,TUBB2B,JAK2,VWA5A,NCOA7,ASPRV1,CD200,MYO9A,CLEC9A,PFKFB3,CDK14,SSH1,CCSER2,PLCL1,SLC22A23,EML5,PLEKHB2,ROGDI,ZDHHC14,RGS12,LRRK2,RTN1,SEMA6D,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,SULF2,TMEM150C,ARC,ATP11A,ATMIN,TCF7,CYB561A3,SIRT1,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,FNDC5,TUBB2A,CLIP2,ZBTB38,SPIRE1,WNK1,ITM2C" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_200 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.58E-05 8.08E-02 9.43E-05 8.59E-04 48 161 "LCORL,BACH1,CALB1,RUNX1T1,CBLN1,CDH10,CHM,SLIT2,COL9A1,RBM39,CRMP1,PUM1,ST18,TCAF1,EDIL3,ELAVL4,MEX3B,SMC2,GAP43,LPAR4,FAM19A2,INSM1,CHIC1,MEIS2,MMP16,NASP,NEFM,PCDH8,GPR85,RGS4,ZFHX4,TMLHE,MEG3,CSRNP3,ARX,CPEB4,SNAP25,SOX2,RBM26,KLHL4,CBX5,ASXL3,TPM1,SSBP2,ZIC1,ZIC3,ADAMTS9,GAN" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.58E-05 8.08E-02 9.43E-05 8.59E-04 48 161 "ADORA1,PCDH19,DOC2A,BMP7,CA4,CALB1,CRLF1,SLC32A1,CRYM,KIAA0040,GREB1,DUSP9,EMX2,EPHB1,RACK1,ST3GAL6,FKTN,SLC9B2,SPSB4,FGFR1,PSD2,RASL10A,GALC,IGSF5,GLDC,ADGRA3,B4GALNT4,PRDM5,HES5,KIF5C,CLEC18A,MID1,NPY,OXTR,PRTG,PLXNB1,LAMA1,NKAIN1,GAL3ST4,TMEM100,PRR5L,EMID1,SALL1,SYT11,HEY1,CA14,LRP8,PCBP4" Coexpression Atlas PCBC_MESO-5_blastocyst_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000 PCBC 1.61E-05 8.19E-02 9.54E-05 8.70E-04 210 979 "KCNH8,CSMD3,ADCY2,SORCS1,NR0B1,UNC79,PDZD4,DPP10,APOC1,LGR5,TMEFF1,ARSE,RASL11B,KIF1A,FGF17,BMP7,BTK,C5,MYRF,MAP7,CCK,CCKBR,USP2,SYNGR3,CDH8,L3MBTL4,PLEKHB1,SLC24A2,TMEM59L,FAM189A2,FAM19A5,SULT4A1,IGLON5,CNR1,COL9A1,COL9A2,COL9A3,AKAP5,GAL3ST1,MYRIP,NRG2,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGEF4,ARHGAP24,KIF26A,RIMS3,DNAJC6,ELMO1,SV2B,SPOCK3,ARNT2,HS3ST4,CALN1,DPP6,DSCAM,FAM78B,USH1C,FAM135B,CNNM1,RASGRP1,EFNA2,ELAVL4,HSD17B14,RCAN2,ERBB4,TMEM74,RASL12,ADGRV1,ATP8A1,FGFR3,C1orf61,RASL10A,B3GAT1,TBR1,MEGF10,HRASLS5,GABRA3,GABRA5,CHL1,GABRB3,GAD1,RAPGEF6,SALL3,SYT17,ATP8A2,GATM,PCDH17,PPARGC1A,GNAL,GPM6A,GPM6B,GPR37,TMEM121B,CECR2,STMN2,GRIK3,ADAMTS8,GRM2,PTPRT,PTPN5,TMEM179,FAM222A,HAS2,PADI2,NXPH3,NXPH2,IGFBPL1,HP,SHISA6,LRRTM1,C2CD4C,KCNF1,KCNH1,CLVS2,KCNJ3,KCNQ2,KIF5C,KIT,MATK,MATN3,MOBP,MSR1,MT3,SCG3,DDX25,MYL3,MYT1,NNAT,NODAL,HCN1,PAX6,PCDH8,SERPINI1,SEMA5B,A2ML1,SNX10,JAKMIP1,PNMA3,PDZRN4,PILRA,PACSIN1,FA2H,RASGEF1B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,KHDRBS2,PRIMA1,LGI2,MRAP2,HUNK,RXRG,SALL1,TMEM200C,SH3GL2,CNKSR2,ANKRD6,SLC1A6,TMEM132D,CABCOCO1,MYO16,SOX10,SOX15,LHFPL4,HECW1,PEG10,MCF2L2,NFASC,SSTR2,AJAP1,ZFR2,TMEM150C,COBL,TAC3,CUX2,PHF24,FAM189A1,LEFTY2,GALNT17,TMOD1,FAM124A,RIMBP2,PIK3R5,SEZ6L,TRO,TRPM2,CA14,RPRM,VIPR2,PORCN,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,PLPP4,ANKS1B,CADM2,SHD,GAL3ST3,FAM198A,JPH3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgBP_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.75E-05 8.94E-02 1.04E-04 9.48E-04 26 69 "TTYH1,SEPT7,CDO1,IGDCC3,EDNRB,EN2,FABP7,C1orf61,ILDR2,HES5,FGFBP3,MN1,MSI1,NPTX2,NTRK2,PCDH8,PLP1,POU3F2,PTCH1,PTPRZ1,VEPH1,RFX4,LIMCH1,SOX2,SOX3,RGMA" Coexpression Atlas PCBC_ratio_MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst_cfr-2X-p05 MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.76E-05 8.95E-02 1.04E-04 9.49E-04 103 424 "TTYH1,EMILIN3,RNF157,ADD2,WDR35,SEMA6A,CNIH2,APLP1,VAT1L,ALDH4A1,ATP1A2,CADM3,BLM,PROM1,CDH8,LGI1,CRLF1,UBE2L6,RCBTB2,SLIT2,LHX2,TMEM59L,HOMER3,CNTFR,COL9A1,TCEAL2,IGDCC3,NECTIN3,ZNF385A,CLIP3,CRYM,DPYSL2,EDN1,EDNRB,RASGRP1,CACNG7,EYA1,FABP7,SPSB4,FLNC,DPYSL4,GAD1,WASF3,MALT1,GLDC,GRIK5,LINGO1,NXPH2,CPT1C,IFI16,LIX1,KCNJ3,FGFBP3,SMAD9,MDFI,MGAT3,KITLG,MN1,MYCN,BEX5,NELL2,CHAMP1,PRTG,CDK14,FAM216A,PCDH18,SDK2,FSD1,PPP1R1A,PPP2R2B,RELN,PTH1R,PTPN13,PTPRZ1,NKAIN1,FEZF2,PRRT2,ARHGEF10L,EMID1,SYNDIG1,TUNAR,WLS,SALL1,TNFRSF19,RASA3,SCG5,YPEL4,SOX2,TNIK,ZNF423,LRRC4,SYT11,PCDHGB7,PCDHGB6,SSBP2,TUB,TCEAL7,DPYSL5,PRTFDC1,SHD,TMEM178A,NAV2,ADAMTS10" Coexpression Atlas GSM538265_500 "Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 1.92E-05 9.80E-02 1.14E-04 1.04E-03 97 395 "FMNL2,PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,ATP1A3,CADM3,ADAM23,ST3GAL5,DDR1,HAP1,CHN2,B4GALT6,ZFYVE9,LY86,ZNF385A,CDC42BPB,CSF1R,CSF2RA,CST3,SDC3,CTNND2,USP6NL,CX3CR1,CYBB,DOCK4,HDAC9,MYADM,SIRPA,DSCAM,ARRDC4,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FGR,SPECC1,GATM,GCNT2,RAB30,GPM6B,ADAP1,GSN,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KCNJ16,KIT,ADAM11,MEF2C,STK32C,LINC00672,MYO5A,MYO9A,CLEC9A,CDK14,ABCB1,PLTP,RASGEF1B,PTAFR,PTK2,TMEM231,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SCN3A,DOCK10,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,KIAA0930,CYB561A3,DDHD1,TNS1,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-2_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-2_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 1.98E-05 1.01E-01 1.17E-04 1.07E-03 74 283 "NDRG2,SPARCL1,LTBP4,PHYHD1,ATP1A2,NRP2,CACNA1D,CACNA2D1,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,RBM39,AKAP12,VCAN,GPSM1,DOCK4,DAPK1,ZEB2,EDNRA,PCOLCE2,LRRC17,NCALD,ETV1,RASL12,FGFR1,FGFR3,FHL1,PNMA2,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,MAPT,CCDC80,NAP1L1,NFIA,NPR2,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SCHIP1,SEPT4,NKAIN4,PTCH1,ACSS3,REV3L,ROBO2,SCN7A,TNFRSF19,SFPQ,SLC1A3,PREX2,LIMCH1,PALLD,ZCCHC24,TACC1,TAF6,PDLIM2,TGFBR3,HHIP,VIPR2,VLDLR,ZSCAN26" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-2_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-2_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.98E-05 1.01E-01 1.17E-04 1.07E-03 74 283 "NDRG2,SPARCL1,LTBP4,PHYHD1,ATP1A2,NRP2,CACNA1D,CACNA2D1,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,RBM39,AKAP12,VCAN,GPSM1,DOCK4,DAPK1,ZEB2,EDNRA,PCOLCE2,LRRC17,NCALD,ETV1,RASL12,FGFR1,FGFR3,FHL1,PNMA2,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,MAPT,CCDC80,NAP1L1,NFIA,NPR2,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SCHIP1,SEPT4,NKAIN4,PTCH1,ACSS3,REV3L,ROBO2,SCN7A,TNFRSF19,SFPQ,SLC1A3,PREX2,LIMCH1,PALLD,ZCCHC24,TACC1,TAF6,PDLIM2,TGFBR3,HHIP,VIPR2,VLDLR,ZSCAN26" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_500 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.01E-05 1.03E-01 1.19E-04 1.08E-03 45 149 "LRRC4C,TMEM108,MYRF,CALB1,CDH10,CNTFR,ZNF521,CLIP3,TENM4,ATRNL1,SV2A,DNM1,ABCA8,EFEMP1,FLNC,GUCY1A2,TCEAL6,NKD1,KCND2,MATN2,MEIS1,MEIS2,MMP16,CCDC80,TCEAL5,NEFM,NFIA,NNAT,PDE3A,PIK3R1,PCDH18,PRRX1,SYTL2,PTN,CCDC112,DZIP1,SLC1A3,PALLD,ZCCHC24,PSD3,ZFPM2,ASXL3,TRPS1,FLRT2,PLEKHH2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.08E-05 1.06E-01 1.22E-04 1.12E-03 58 208 "ARHGAP20,LRRC4C,MYRF,CACNA2D1,KALRN,CBLN1,CDH10,LARGE1,SLIT2,CNTFR,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,ZEB2,SV2A,DNM1,TSPAN5,EDNRA,SEMA3D,FABP7,EFEMP1,FGFR1,CAP2,FLNC,DENND2A,FREM1,GHR,GLI2,GUCY1A2,GUCY1A1,GUCY1B1,NKD1,MATN2,MEIS1,MEIS2,NCAM1,NEFM,NNAT,PDE3A,PDGFRA,PCDH18,PRRX1,FAT3,SYTL2,LAMA1,PTN,ROBO2,SCN2A,PKNOX2,PALLD,ZCCHC24,ASXL3,TRPS1,TMEFF2,PLEKHH2,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k3 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.08E-05 1.06E-01 1.22E-04 1.12E-03 58 208 "TAOK1,APC,DDO,ATP1A2,ADAM23,GPR146,CACNA2D1,PLEKHB1,AKAP6,CLOCK,OSBPL3,MFAP3L,KBTBD11,CHRDL1,CPEB2,ABCC9,HIPK3,TMTC1,MBNL2,PCOLCE2,RCAN2,MRVI1,NRN1,EFEMP1,CAP2,PHYHIPL,DKK3,DNER,GCNT2,GSN,HLF,KCNA1,KCNF1,KCNMA1,MAP4,MBP,NFIA,CCSER2,PLCL1,PLP1,DIRAS2,PTPRZ1,RGS4,TTLL7,CLIP1,SCN7A,CPEB3,CPEB4,SYN2,HHIP,NACC2,ERCC6L2,RGMB,ZBTB38,PLSCR4,FAM13C,DOCK8,SSPN" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_1000 kidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.13E-05 1.09E-01 1.26E-04 1.14E-03 185 850 "CPNE2,RALGAPA1,NDRG2,FMNL2,USP31,MTUS1,HECW2,ADGRF5,SPARCL1,SEMA6A,AMPD3,SEMA7A,C6orf89,MAP4K3,APBB2,APP,ARNTL,DDX3Y,ATP1B3,ADAM15,NRP2,GPR146,CFLAR,PROM1,SYNJ1,MTMR2,IL33,CA8,CAMK2D,CAST,CH25H,CBLN1,CLDN10,LDB2,FMNL3,CD38,CD81,ADGRG1,CHN2,JAM2,TAOK2,CLTB,ABCG2,TMEM184B,ARHGEF6,CLOCK,ANKRD44,ABCG1,SNCAIP,CSF1,FEZ2,CST3,PLXNA4,PPP1R16B,SDC3,DOCK4,KIAA0513,PITPNC1,ELMO1,NR1D2,GNE,ECM2,EBF1,EDN1,EDNRB,SEMA3D,KLHL5,TMTC1,MBNL2,LPAR6,IRAK4,CALCRL,RCSD1,EZH1,F8,DLC1,ATP8A1,ST3GAL6,CHST15,KIAA1109,FLT1,PDLIM5,TRIM16,ST6GALNAC3,GALNT15,ERAP1,INPP5K,PCDH17,GGTA1P,FERMT2,GPM6A,LPAR4,RAPGEF4,NR3C1,IRAK3,HLF,ICA1,IFI16,IGF1,SCIN,IL6ST,ITPKB,STXBP5,INSYN2,LIFR,LMO2,VWA5A,SMAD1,AQP11,TM6SF1,MEF2C,MEIS2,CD200,MYO6,NFE2L2,NFIX,CLEC9A,PBX1,PDE2A,PFKFB3,SERPINE2,PLTP,PMP22,SEPT4,SLC36A4,DRAM2,MINDY2,RASGEF1B,PROX1,SNRK,PTPRB,PTPRG,RIPOR1,ZDHHC14,RDX,LRRK2,MAPK12,ATXN1,SCN2A,FNIP1,SGK1,MAGI3,PREX2,EPN2,SMTN,LIMS2,SLC14A1,SLC15A2,SLCO1A2,CPEB4,LIMCH1,LMBRD1,ZHX3,ARHGAP26,SPTAN1,COLGALT2,ITPRID2,THSD1,RGL1,STXBP1,C3orf70,PLCB1,ANKRD28,ANKRD12,ROBO3,KLHL4,VWA3A,TCF4,SYNE1,DOCK9,TNS2,TEK,C18orf54,TGFBR3,SLC44A1,TIE1,TJP1,TLR4,TNS1,TRPC3,UCHL1,AGMO,SLC26A10,ZBTB38,PLSCR4" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k1 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.19E-05 1.12E-01 1.29E-04 1.17E-03 65 241 "ABAT,ABR,ASIC2,INTS2,VAT1L,BBS2,BCHE,OSGIN2,IL33,CACNA2D1,CH25H,ZFP28,NSL1,SNCAIP,VCAN,RIMS2,CENPL,MTX3,ARRDC4,ABI2,CDHR1,ADGRV1,ST3GAL6,CAP2,FAM49B,DACH2,MEGF10,SRCAP,BRD8,TDRKH,PSIP1,NEGR1,NRDC,ING3,EPDR1,PIGG,PPP2R3C,FAM184A,ENOX1,CRTAC1,RPS20,SALL1,ZFP2,SFPQ,SUPT20H,TRA2B,HSPA4L,PPM1E,SLC12A2,MBD5,SOX11,NEK4,ANKRD28,PCDHB9,FRYL,TPM2,RGMB,STXBP4,TSN,RPL7L1,NSD2,XRCC4,ZFAND5,PHTF2,SOCS4" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.21E-05 1.13E-01 1.30E-04 1.18E-03 69 260 "ABAT,CSMD3,FMNL2,SLITRK1,KLHL13,NR0B1,KCNT1,PPP4R4,NUMB,ATP2B3,WASF1,CACNB2,CALB1,SLC16A4,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,ABI2,TMEM35A,EMX2,EPB41L1,MTSS1L,GABRA4,GALC,DHRS4,PCDH11X,GRIK5,PACSIN2,SHISA6,KLHL23,AFF1,MYO9A,SLC11A2,NUCB2,SERPINI1,PIK3C2A,PPP3CC,PTPRG,REV3L,ZFHX4,LGR4,HUNK,RASA3,ST8SIA1,SLC4A3,SNCA,UHRF1BP1L,SMOC1,ST5,ADGRL3,DOCK9,OBSL1,CCDC173,DNAH7,ZFPM2,ACTR6,KAT6B,FNDC5,VAV2,ZNF23,ELFN1,NAV2,DPF3" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k4 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.22E-05 1.13E-01 1.30E-04 1.19E-03 33 98 "LCORL,CHM,KMT2C,NMT2,ABI3BP,RBM39,DZIP3,FGFR1OP2,CALCRL,EMX2,SCML2,KIAA1109,MEX3B,GABRA4,ILDR2,KIF3A,ZNF385B,HECTD2,CNOT4,PDPK1,OLA1,TMLHE,FNIP1,SLC12A2,SCMH1,TNIK,SYNE2,ANKRD12,WASHC4,AHCYL2,TSC1,ZNF711,ADAMTS9" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500 gudmap_RNAseq_p2_CD2APMEISWT_2500 Gudmap RNAseq 2.24E-05 1.14E-01 1.31E-04 1.20E-03 363 1822 "CPNE2,ABAT,ACADM,ACHE,AS3MT,C3orf14,NDRG2,ADCY6,ADD2,ADORA1,ADORA2A,RNF150,ESYT2,C1QTNF1,BCAR3,TRMT9B,AMPD3,PI16,MAP4K3,PPFIA2,ANXA7,APBB2,FAM131A,BCAS1,APP,ARNTL,ARRB1,PDE8B,MARK4,RASL11B,ATP1A1,ATP1B3,ATP6V1G2,MYOM1,NRP2,GPR146,CFLAR,KSR1,ST3GAL5,RAB29,LDLRAD4,CACNA1A,CACNA2D1,CAMK2A,CAST,ARHGEF25,FMNL3,CD81,LRRFIP1,DLGAP1,UBE2L6,CHN1,NRXN3,PPT2,STOML1,CLTB,QKI,TMEM184B,IGLON5,ARHGEF6,AKAP7,CABP1,IFFO1,CP,PNKD,CLOCK,AKAP12,ANKRD44,ABCG1,AATK,CSF1,FEZ2,MICAL2,SOCS5,CST3,SDC3,USP6NL,HDAC9,MYADM,RIPOR2,ACY3,DGKB,IP6K1,PITPNC1,ZNF804A,ZEB2,RUSC2,SV2A,SGSM2,DMPK,NR1D2,MAMLD1,ABCC9,FIS1,EBF1,TSPAN5,EDN1,HEYL,TMTC1,FRY,OPTN,GOLGA7,IRAK4,EML1,CALCRL,EPB41L2,RCAN2,LRRC17,RASGRP2,EPHB1,EPS8,NCALD,SPEG,RCSD1,TLR7,RASL12,CEND1,MRVI1,TAOK3,DLC1,ST3GAL6,CHST15,TOMM40L,FCGRT,FGF1,FHL1,VTI1B,ZMYND15,SORBS1,SPECC1,NPTN,CAMKK2,KHDRBS3,GPR153,SARAF,TPPP3,TMEM151A,HIGD1B,ERAP1,TUBA8,GDF9,GGT7,GGT5,RUNDC3A,NTNG2,LOXL3,FERMT2,GPM6B,FUT10,CCDC184,STON1,RAPGEF4,SERP2,NR3C1,ATE1,GRM7,GSN,COQ10A,GSTM5,GSTT2,GUCY1A2,GUCY1A1,GUCY1B1,SLC2A6,ATOH8,GYG1,IRAK3,RASSF8,TOX2,FRMD3,KLF12,HLF,GABARAPL2,SYNPO,LRRC75A,IFI16,IL6R,IL6ST,IL11RA,INPP5B,ITGA7,ITGAV,ITPKB,JAK1,JAK2,KCND3,KCNJ5,KCNK3,KIFC3,TTYH2,LAMP2,CAMK2N2,LIFR,VWA5A,GPR155,MAN2A2,MAP6,MAPT,MARK1,MBNL1,SHC3,MEF2C,MITF,MMP17,CD200,CCDC80,NRBP2,MX1,LAYN,RTL5,NCF2,IDNK,NFIX,NRGN,NTRK2,NTRK3,OGG1,P2RX7,PDE1A,PDE3A,PDE4A,PDGFRA,CDK14,ABCB1,SERPINE2,SERPINI1,SSH1,PIK3CD,PIK3R1,CCSER2,PKD1,PLCB2,PLCL1,PLEC,FXYD1,PCDH18,PLTP,SPATA6,SEPT4,SH3KBP1,PPARA,PRKAB2,PKIA,SNRK,TMEM104,PTH1R,PXK,PTN,PTPN13,PTPRB,PTPRG,PYGM,ZSCAN2,RAB3A,RAB5B,PLEKHB2,C1orf54,FAM184A,RASGRF2,ZDHHC14,ZMAT4,RET,PRRT2,RGS3,RGS4,ARHGEF10L,ROM1,PRR5L,EMID1,PTGR2,PAQR6,WLS,MAPK12,ATXN1,FAM19A1,PRCD,PEAR1,GALNT10,RASA3,SGK1,SH3BP2,DOCK10,PREX2,EPN2,SMTN,LIMS2,SLC8A1,SLC12A2,SLC12A4,SLC15A2,ELMO2,CPEB4,ABTB1,RIMS1,CABCOCO1,LMBRD1,FAM219A,ZCCHC24,UNC5B,ARHGAP26,DBNDD2,SPTAN1,IQSEC2,CDK19,CAMTA2,ITPRID2,NKAIN2,ST5,MPRIP,SEPT8,RGL1,STXBP1,C3orf70,SYP,TACC1,PDLIM2,ADGRL3,TBCEL,TMEM136,SYNE1,ARHGEF12,TNS2,GPRIN3,CYB561A3,TEK,TF,CHST8,TGFBR3,GALNT17,THRA,ENHO,NACC2,TK2,TLR4,DAAM2,TNFRSF1B,TNS1,TPM2,IL34,TRPC1,RFTN2,TMEFF2,UBC,UBE2H,PLEKHH2,VAV2,TOM1L2,CLIP2,NPDC1,ZBTB38,SH3GLB2,ZFAND5,SHD,RGMA,TMEM178A,ITM2C,PLSCR4,FAM13C,DOCK8,MSRB3,SSPN,PIANP,CPNE4" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k4_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.34E-05 1.19E-01 1.37E-04 1.25E-03 21 51 "SEMA7A,MARK4,JAM2,PPP1R16B,TOX,GNE,MBNL2,FAM198B,FYN,GATM,TUBB2B,ITPKB,RPS6KA2,FAM102A,SPP1,ARHGAP26,TACC1,TRPC3,DCBLD1,ADAMTS9,NHSL1" Coexpression Atlas GSM605808_500 "gamma delta T cells, Tgd.vg5-.act.IEL, CD8a+ CD8b- TCRd+ Vg5- CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 2.39E-05 1.22E-01 1.40E-04 1.27E-03 98 402 "ABR,GRAMD1B,MTA3,APLP1,BAIAP3,LDLRAD4,CAPN3,HIP1R,CD38,RCBTB2,CHN2,FADS2,LRIG1,OSBPL3,IPCEF1,PPP1R16B,TOX,PITPNC1,DNAJC6,SRGAP3,RABGAP1L,ARRDC4,HEYL,RASGRP1,EPB41,DENND4A,EZH1,ST3GAL6,FDFT1,FGR,FOXO3,HVCN1,NSG2,FYN,RAPGEF6,IGSF5,GCNT2,HPGDS,B4GALNT4,GPR34,PADI2,ACOT7,HMGCR,ZDHHC15,CFAP126,AGFG1,SMAP1,SCIN,ITGAV,KCNK1,KIT,STXBP5,HECTD2,SESN3,STK32C,NEFH,P2RX7,ZNF827,PDE3B,PFKP,ABCB1,PLTP,SEPT4,PPM1B,PPP2R2C,PPP2R5C,PPP3CC,PRKACB,SYTL2,SIDT1,SUSD4,PRR5L,EMID1,WLS,ATXN1,SEC14L1,FAM102A,ELMO2,TRERF1,TNIK,SPP1,TEX2,SULF2,ACSBG1,TCF7,AKNA,FRYL,C18orf54,TNFRSF1B,PRRT1,TRIO,RUNDC3B,TTC3,VIPR2,LAT2,PMEPA1,MVB12B,CERS6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.40E-05 1.22E-01 1.40E-04 1.28E-03 14 27 "TTC9B,INA,CNTFR,CRMP1,EDNRB,GFRA2,TAGLN3,NELL2,SLC10A4,GDAP1L1,RGS4,SCG5,SYP,UCHL1" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_500_k1 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.40E-05 1.23E-01 1.40E-04 1.28E-03 27 74 "ADORA1,PCDH19,DOC2A,EPB41L5,CDC14B,TENM4,KIAA0040,GREB1,SCRN1,HEYL,ST3GAL6,FGFR1,SALL3,IGSF5,ADGRA3,B4GALNT4,GPER1,FAM107A,IGSF1,HES5,CLEC18A,OXTR,PLXNB1,NKAIN1,EMID1,SALL1,HEY1" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000_k3 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.54E-05 1.29E-01 1.48E-04 1.35E-03 39 124 "PDE8B,BMPR1B,CACNA1D,CALB1,LRBA,B4GALT6,SLIT2,FAM149A,NECTIN3,IPCEF1,MFAP3L,TENM1,EMX2,ENO2,SPSB4,C2orf88,GFRA1,GRIK2,PADI2,KCNK1,L1CAM,KITLG,VWA2,EML5,FAM184A,RASGRF2,RET,PRR5L,SCN8A,LINC00461,TRA2B,NUDT10,TMEM150C,CUX2,DCBLD1,RPRM,EMX2OS,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 2.65E-05 1.35E-01 1.54E-04 1.41E-03 52 182 "ERMN,TMEM108,CA4,CBLN1,INA,CLCN3,FAM169A,HDAC9,CHRDL1,ST8SIA3,PLEKHA1,SEZ6,PIPOX,REEP2,TUBB4A,FGF11,SYT3,JPH4,SALL3,GPD2,LPAR4,CECR2,HSP90AA1,CDH20,IPO5,AQP11,CD200,CCDC80,IGSF11,PRTG,PDE1A,SNX10,PKM,MAGEL2,PTPN13,EMID1,SALL1,NTNG1,SNRPN,BEX1,PBLD,AJAP1,ADAMTS17,MTCL1,ROBO3,WASHC4,BEX4,FLRT1,ZIC2,ZBTB16,CA10,SLC38A1" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_500 kidney_P0_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.68E-05 1.37E-01 1.56E-04 1.42E-03 76 295 "ABR,NDRG2,RNF157,ALCAM,AMPH,VAT1L,SEMA4G,CASK,BCHE,DST,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,PHF19,SPOCK2,GSDME,SNAP91,ARRDC4,DTNA,EDNRA,ELAVL4,CALCRL,KCNMB2,ETV1,EYA1,ST3GAL6,FGF1,FGFR1,SCARA3,CAP2,IGSF5,GFRA1,FREM1,GLRB,TDRKH,CECR2,FAM107A,HAS2,NEGR1,MEIS2,MEST,MMP16,NCAM1,NELL1,NME4,CNTN3,PRTG,PENK,SMOX,FAT3,PPP1R1A,MDGA2,RAVER2,ROBO2,TMEM100,HUNK,SALL1,SLC1A3,SLC4A3,SLC12A2,SULF2,NUDT10,ADAMTS17,CUX2,TPM2,CADM1,LAMP5,SIGLEC10" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.86E-05 1.46E-01 1.66E-04 1.51E-03 178 817 "CCDC85A,ADORA2A,ADRB2,ZNF608,HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,BIN1,SUGT1P4-STRA6LP-CCDC180,APBB2,DGKZ,UPRT,SHROOM2,ARRB1,DOCK11,ADAM15,BACH1,NRP2,ARHGEF7,C1QC,CA8,LDB2,FMNL3,CD38,ARHGEF2,CHN1,MS4A7,TAOK2,ABCG2,TMEM184B,MAP4K4,LY86,ARHGEF6,ZNF521,CNRIP1,CREM,CRMP1,HAPLN1,CSF1R,FEZ2,CX3CR1,CYBB,DOCK4,TOX,RASSF2,GIT2,DBN1,ARMCX4,PITPNC1,JAKMIP2,ELMO1,FAM107B,CCDC3,EBF1,EDIL3,EDN1,EDNRB,SH3GLB1,LPAR6,PLEKHA1,CALCRL,PLEKHO1,DMTN,RASGRP2,STX2,DENND4A,CEP85L,CORO2B,DLC1,KIAA1109,IQCG,FLT1,UFM1,PDLIM5,TRIM16,ST6GALNAC3,FYB1,FYN,NEK6,GAP43,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,GPM6A,LPAR4,RAPGEF4,STMN2,MAP4K5,NCKAP1L,ZDHHC15,AGFG1,ICA1,IGF1,KIT,INSYN2,LIFR,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,MYO6,CLEC9A,OPHN1,PALM,PDE2A,PDE4B,PDE4D,GNG2,PFKFB3,SPATA6,DRAM2,RASGEF1B,PROX1,SLC22A23,SNRK,MDGA2,PTK2,PTPRB,RIPOR1,TMEM255A,C1orf54,RDX,PRR5L,SEMA6D,RASA3,SGK1,FAM102A,MAGI3,SLA,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,FNBP1,UNC5B,PEG10,SAMSN1,THSD1,RGL1,STXBP1,ARHGEF9,PLCB1,TACC1,KLHL4,TCF4,DOCK9,TEK,TF,ZFPM2,C18orf54,TIE1,HEY1,TJP1,TLR4,NPL,TRPC3,DCBLD1,RFTN2,TTPA,FLRT2,WIPF1,ZNF711,WNK1,ADAMTS9,NAV3,FAM13C,DOCK8,JMJD1C,NHSL1,RNF146" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO bone marrow_cfr-2X-p05 ECTO blastocyst_vs_ECTO bone marrow-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 2.90E-05 1.48E-01 1.68E-04 1.53E-03 45 151 "AXIN2,ADORA1,PCDH10,CNIH2,RASL11B,NRP2,LARGE1,NOG,SLIT2,IGLON5,COL9A3,COL11A2,HAPLN1,TENM4,PDE4DIP,LYPD1,EDIL3,EDNRA,EPHB1,TMEM132C,DPYSL4,GAP43,ITPKB,KCNA1,KIT,CLEC18A,SAMD5,NPY,PDE2A,SERPINE2,IRX1,ZFHX4-AS1,LRRN3,RELN,GDPD2,RFX4,TNFRSF19,SLC30A10,TMEM200C,SLIT1,SPP1,TAC1,DNMBP,TMEFF2,LMF1" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_100_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.96E-05 1.51E-01 1.71E-04 1.56E-03 20 48 "PNMA8B,BACH1,RUNX1T1,SLIT2,PLAA,ZEB2,ZC3H11A,EIF4G1,EPB41L2,LPAR4,WIF1,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,FLRT2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k1 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.16E-05 1.61E-01 1.83E-04 1.66E-03 18 41 "CHGB,COL9A1,COL9A3,EBF1,ELAVL4,FABP7,GFRA2,STMN2,NEGR1,INSM1,MAP4,CLDN11,MAPK10,PRPH,RGS4,SPHKAP,SNAP25,SCN3B" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.21E-05 1.64E-01 1.85E-04 1.69E-03 48 165 "ALCAM,ARHGAP20,LTBP4,CACNA2D1,ISPD,RUNX1T1,ARHGEF25,CBLN1,SLIT2,ZNF521,TENM4,MICAL2,VCAN,RIPOR2,ARMCX2,ZEB2,EDNRA,EGFR,LRRC17,FABP7,DLC1,FLNC,GFRA2,FREM1,GHR,GLI2,GRIA4,GUCY1A1,GUCY1B1,NCAM1,PCDH9,PDGFRA,PLTP,FAT3,LRRN3,LAMA1,PTCH1,PTN,ROBO2,ARMH4,ACER3,PALLD,SULF2,TGFBR3,HHIP,TPM1,TMEFF2,STOX2" Coexpression Atlas gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1 gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1 Gudmap RNAseq 3.34E-05 1.70E-01 1.92E-04 1.75E-03 184 851 "AS3MT,RNF157,SLC12A5,ESYT2,MTUS1,LTBP4,PITPNM2,ANXA7,APBB2,GAS7,DGKZ,ARNTL,MARK4,NUMB,ATP1A1,ATP1B3,RIPK1,CFLAR,ST3GAL5,ARHGEF7,RAB29,LDLRAD4,THSD7A,CAMK2D,CH25H,FMNL3,SCARB1,ARHGEF2,KCNAB3,CCPG1,JAM2,TAOK2,PPT2,CLU,TMEM184B,IFFO1,MFSD4A,CLOCK,CDC42BPB,C2CD2,CREM,AKAP12,ANKRD44,SOCS5,PLXNA4,PPP1R16B,CYBB,DOCK4,MYADM,PITPNC1,RUSC2,C2CD2L,TMCC2,CPEB2,SLC12A6,RCAN1,GNE,ARRDC4,ECM2,SNX29,SYT15,KLHL5,TMTC1,EGR3,SORBS3,IRAK4,ELN,EML1,PLEKHO1,STX2,NCALD,CEP85L,EZH1,HSPA12B,REEP2,CORO2B,ATP8A1,TOMM40L,BAIAP2,VTI1B,IQCG,ZMYND15,PDLIM5,CAMKK2,ST6GALNAC3,SARAF,FYN,GALNT15,INPP5K,GATM,GCNT2,PCDH17,GGTA1P,RND1,ATF7,STON1,STMN2,RAPGEF1,IRAK3,RASSF8,GABARAPL2,ICA1,INPP1,LRRTM3,JAK1,KHK,KLC1,INSYN2,LIFR,VWA5A,NCOA7,MBNL1,MEIS2,MYO6,MYO7A,IDNK,PBX1,PCSK5,PDE4A,PFKP,CCSER2,PKD1,SPATA6,DRAM2,MINDY2,PPP3CA,PPP3CC,MAPK3,SNRK,TMEM104,PXK,PTPRG,RIPOR1,RAB5B,BSDC1,RGS3,CYB561D1,PCMTD2,RPS6KA2,LRRK2,PTGR2,SEMA6D,SCP2,SEC14L1,PPM1E,FAM81A,EPN2,SMTN,SLC15A2,EFHD1,ABTB1,LMBRD1,TEX2,ARHGAP26,SPTAN1,IQSEC2,PHLDB1,STXBP1,C3orf70,PLCB1,SYPL1,MCF2L,WSCD1,SYNE1,DOCK9,PSD3,CYB561A3,TGFBR3,TIAM1,TK2,HEY2,LRRC8A,DCBLD1,TUBB2A,SGK3,UCHL1,FAM181B,MTCH1,NPDC1,AGMO,LYPD6,KLHDC1,PIANP,SPATA13" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_500 kidney_P2_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.36E-05 1.71E-01 1.94E-04 1.77E-03 75 292 "ABR,RNF157,MTUS1,ALCAM,AMPH,VAT1L,ADAM23,BARD1,BCHE,BCL7A,BMP7,IL33,CA12,CACNA2D1,CACNB4,CDH2,CNTFR,CRYM,SNCAIP,VCAN,CTH,PHF19,SPOCK2,GSDME,SNAP91,DTNA,EDNRA,HEYL,ELAVL4,KCNMB2,ETV1,EYA1,ST3GAL6,FGFR1,SCARA3,TMEM107,STAU2,MTHFD2,IGSF5,GFRA1,FREM1,GLRB,TDRKH,CECR2,FAM107A,HAS2,NEGR1,MEIS2,NCAM1,NELL1,NME4,NPY,CNTN3,PENK,FAT3,MDGA2,TSPY26P,RAVER2,ROBO2,TMEM100,SALL1,SLC1A3,SLC4A3,SLC12A2,NUDT10,CUX2,TRIM2,PCDHB9,HEY1,TPM2,CADM1,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500 FaceBase_RNAseq 3.36E-05 1.72E-01 1.94E-04 1.77E-03 114 486 "EMILIN3,NDRG2,ADCY2,KIAA1324,ARHGAP20,LTBP4,GPRASP2,ANK1,CDK10,ASCL1,BACH1,ADGRB2,BMPR1B,C1QC,CACNA1G,CA4,CA12,CACNA1B,REPS2,CDO1,TBRG4,CRLF1,SRSF11,LHX2,IGDCC3,CREB5,CRYM,CSF1,CSF1R,FEZ1,GREB1,TOX,CCDC3,SEMA3D,EFNA2,EGFR,ELN,EMX2,LRRC17,EPHA5,F3,DLC1,FCGRT,FGF11,FOXG1,TPK1,FYB1,JPH4,ACSS1,GATM,PCDH17,PPARGC1A,ZNF276,PCDH11X,GPT2,CECR2,GRIK2,NR3C1,GSN,RABL2A,WIF1,SYNPO,IL11RA,INPP1,MBNL1,ADAM11,SRSF12,CD200,CCDC80,NCAM2,NELL2,NFIA,NFIX,NNAT,CLEC9A,CNTN3,PCDH9,PRTG,PLCL1,SCHIP1,POLR2F,PRODH,FEZF2,ZMAT4,SOX8,RTN1,SALL1,ATXN1,NTNG1,MAST1,LIMCH1,TNIK,SMOC1,ZFR2,PLCB1,ADGRL3,WASHC4,PHF24,FAM189A1,HEY1,NR2E1,TMOD1,KCNE5,TSPAN11,ZIC2,FMN2,ZBTB16,LAMP5,PMEPA1,CADM2,LRP8,PCDH15,PCBP4,SENP7" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k2 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.40E-05 1.73E-01 1.96E-04 1.78E-03 62 230 "NDRG2,ADCY5,ADCY8,SRPX,ARHGAP20,ATP1A2,MYOM1,BMPR1B,VSTM2A,RGN,DCLK1,CP,FEZ1,MFAP3L,CHRDL1,CALN1,EDN3,EDNRA,EDNRB,ING4,ETV1,EFEMP1,FCGRT,FGF1,FGF12,FHL1,UFM1,GABRB1,GAD1,LYVE1,TNRC6A,GLUL,CNDP1,GSN,HLF,IGFBP1,KCNC2,KCND3,KCNK1,GPR155,MATN2,MYH3,MYO6,VWA2,NPY,PCSK5,PENK,NALCN,FAT3,C1orf54,VEPH1,LGI2,MRAP2,ATXN1,SLC15A2,TRIM2,WASHC4,PCDHB9,TNNT1,RPRM,VLDLR,RGS7BP" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_500 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.42E-05 1.74E-01 1.96E-04 1.79E-03 56 202 "ABR,RNF157,AMPH,VAT1L,BARD1,BCL7A,BMP7,CACNB4,CDH2,CNTFR,CRYM,SNCAIP,VCAN,PHF19,GSDME,SNAP91,DTNA,ELAVL4,KCNMB2,ETV1,EYA1,FGFR1,SCARA3,TMEM107,STAU2,MTHFD2,IGSF5,GFRA1,FREM1,TDRKH,CECR2,FAM107A,HAS2,NEGR1,NCAM1,NELL1,NME4,NPY,CNTN3,FAT3,MDGA2,TSPY26P,TMEM100,SALL1,SLC1A3,SLC4A3,NUDT10,CUX2,TRIM2,PCDHB9,HEY1,CADM1,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_1000_k1 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.55E-05 1.81E-01 2.04E-04 1.86E-03 15 31 "BACH1,DBN1,GSDME,ELAVL2,TUBB2B,KLC1,MAPT,NNAT,PCDH8,ROBO2,SNRPN,SOX2,RBM26,PCBP4,VANGL2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k5 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.55E-05 1.81E-01 2.04E-04 1.86E-03 15 31 "CHGB,SPOCK3,TUBB3,DNER,STMN2,IFI16,KIF5C,MAP4,MYH3,NEFM,MAPK10,PRPH,SNAP25,C11orf87,HHIP" Coexpression Atlas GSM605872_500 "Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 3.62E-05 1.85E-01 2.07E-04 1.89E-03 99 411 "AP2A2,MTUS1,ALCAM,ABCD2,AMPD3,GAS7,APOC2,APP,CASK,ATP1A3,ATP2B1,ADAM15,BACH1,SCARB1,SOCS6,B4GALT6,ZFYVE9,LY86,GDA,CSF1R,CSF3R,ATRNL1,VCAN,SDC3,CTNND1,CX3CR1,CYBB,DOCK4,MYADM,ARHGAP24,KIAA0513,DGKG,SIRPA,ZEB2,FBXL5,ARRDC4,EPS8,IGSF6,TLR7,SIRPB1,F5,FCGR1A,FCGR3A,OLFM1,FGR,CAMKK2,TPPP3,GCNT2,ADAP1,ATG4C,IRAK3,HP,IFI16,LRRC25,DOCK7,IL6R,ITGAM,LAMP2,LIFR,VWA5A,LDLRAD3,TM6SF1,MSR1,MX1,NCF2,P2RY1,CDK14,PILRA,DRAM2,VPS13C,PTAFR,MTMR10,PID1,C1orf54,ATP8B4,ACER3,LRRK2,SELL,SH3BP2,SLC8A1,CCDC88A,SLC11A1,ZCCHC24,ARHGAP26,SULF2,FGD4,PLCB1,ATP11A,DMXL2,TF,TIAM1,TLR4,TNFRSF1B,TPD52,TRPS1,EVI5,PLD4,CERS6,NLRP3" Coexpression Atlas geo_heart_500_K3 geo_heart_top-relative-expression-ranked_500_k-means-cluster#3 PCBC 3.66E-05 1.87E-01 2.09E-04 1.91E-03 52 184 "SERPINA3,TKTL1,ACTN2,ADCY5,AGT,C1QTNF1,CPNE5,ATP1A3,LDHD,C1QC,CACNB2,CAMK2A,MYOM2,CHI3L2,LSMEM2,CSF1R,PDE4DIP,EEF1A2,RCAN2,FCGR3A,FOLR2,SORBS1,KBTBD12,IP6K3,CSDC2,GPD1,GPR17,UBE2QL1,INSYN1,HLF,VSIG4,HPR,ITGA7,MAOB,MT3,MYL3,NCAM1,DUSP26,PHKG1,PLCL1,PLIN1,FXYD1,PYGM,RNASE1,KCNIP2,SCN7A,SLC4A3,LIMS2,SLC8A1,SPHKAP,FAIM2,VIPR2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal B_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.79E-05 1.93E-01 2.16E-04 1.97E-03 83 332 "NDRG2,AXIN2,AGT,SPARCL1,LTBP4,USP37,NCOA1,MTMR3,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,SNCAIP,VCAN,GREB1,DOCK4,ZEB2,CCDC3,EDNRA,EDNRB,PCOLCE2,LRRC17,ETV1,FGFR1,FHL1,NOP56,CINP,STAG2,DKK3,FREM1,CSDC2,FERMT2,GPM6B,GPER1,GRB10,ATE1,GSN,GUCY1A1,GUCY1B1,GYG1,WIF1,IGF1,KCNK3,LDLRAD3,MYO9A,NUCB1,PBX1,PCDHGC3,PCSK5,PDGFRA,ENPP2,PENK,SERPINE2,PIK3R1,PKD1,FXYD1,PMP22,EXOSC10,SEPT4,NKAIN4,CNTLN,PTCH1,OCIAD1,ROBO1,ROBO2,ZNF354C,TNFRSF19,DZIP1,LIMCH1,PALLD,PDZRN3,SOX5,KANK1,PDLIM2,TCEA1,TGFBR3,HHIP,SSBP2,PMEPA1,ADAMTS10" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_k3_500 kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.80E-05 1.94E-01 2.17E-04 1.98E-03 48 166 "ADORA1,LGR5,BCL7A,BMPR1B,CACNA1G,CHN2,SLIT2,TENM4,GREB1,SCRN1,SV2B,NTM,EMX2,HSD17B14,IGSF5,FAXC,TOX3,KDM2B,ADGRA3,CECR2,KIF5C,CLEC18A,TM6SF1,MID1,MSI1,NPY,PRTG,KCTD15,PLXNB1,SDK2,MAPK4,LAMA1,PTPN13,ROBO1,GLDN,FHOD3,CNKSR2,PDZD2,SOX11,NUDT10,TACR1,CUX2,HEY1,TRPS1,PLPP4,SLC38A1,ADAMTS9,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k2 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.81E-05 1.94E-01 2.17E-04 1.98E-03 46 157 "ANK1,MYOM1,NGB,CAMK2D,NEURL1,CFL2,RAB3C,AKAP5,RABGAP1L,EML1,PLEKHO1,PRKAG2,FERMT2,PRUNE2,BVES,HNMT,SHISAL1,IL6ST,KCNB1,IL17D,MMP17,MYH3,MYH7,ALDH1L2,NPTX2,TMEM38A,SCHIP1,PRKCB,PSD,RYR3,SCN2A,STUM,SH3BGR,FHOD3,ABLIM3,TNIK,FNBP1,DBNDD2,SRPK2,ARHGEF9,TEX15,ENHO,PPIL6,MICAL1,RBFOX3,ACTR3B" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_500 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.83E-05 1.95E-01 2.18E-04 1.99E-03 31 92 "EMILIN3,ALCAM,APAF1,PHYHD1,BCHE,NRP2,CACNA2D1,VCAN,ETV1,DLC1,PDLIM5,PCDH17,GHR,PCDH11X,RASSF8,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,SOX5,ZHX3,PEG10,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,UBE3A,WRN,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_100_k3 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.83E-05 1.96E-01 2.18E-04 1.99E-03 23 60 "C1QTNF3,DPP10,IL33,SEMA3D,TMTC1,GABRA1,GLRB,GRIA1,GRIA4,GRM3,RASSF8,IFI16,KCND2,NOVA1,RELN,CSRNP3,SCN3A,SCN7A,FAM19A1,ST8SIA1,SLCO1A2,PCDHB9,PCDH20" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.87E-05 1.97E-01 2.20E-04 2.00E-03 76 298 "ARID1A,CEP126,SPTBN4,ADAM23,ZNF599,SCAPER,PTBP2,CDK11B,CDO1,CRLF1,CLTB,VAX2,NIPBL,COL9A2,IGDCC3,CLIP3,PHF14,C8orf34,DRP2,DNM1L,ABCC9,ELN,WAC,CORO2B,HPCAL4,STAU2,ADGRA1,C15orf41,GLRB,ZNF638,GOLGB1,HPSE2,SYNPO,SMAP1,ICA1,KNDC1,LRRCC1,LIX1,IL11RA,HECTD2,MID1,CPNE9,MSR1,RSPO2,TCEAL5,NASP,NFIX,CLEC9A,PDE4D,GPSM2,TRHDE,DIRAS2,CNTLN,ACSS3,IQSEC3,REV3L,MYH14,DOCK10,PREX2,CCDC88A,LIMCH1,TNIK,SPATA7,BDP1,ARHGAP26,TMEM136,SATB2,LEFTY2,ASXL3,LRRC8A,STXBP4,TRPS1,PMEPA1,TMEM163,CAB39L,CERS6" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Proliferative Myofibroblast Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Proliferative Myofibroblast Lungmap CCHMC 3.93E-05 2.00E-01 2.23E-04 2.03E-03 105 442 "SDE2,FMNL2,CDC7,ANK2,LCORL,CASK,ASPH,RASL11B,ALDH7A1,DST,CACNB2,RUNX1T1,NFS1,FMNL3,CBFA2T2,LRRFIP1,MAGI1,COPB2,CHN2,CLU,TBPL1,SNCAIP,TENM4,SEC24C,GPSM1,TCAF1,DCAF8,MATR3,SV2A,FAM107B,CD99L2,EDNRB,TNK2,CALCRL,CAMSAP1,FOXF2,DKK3,SEPT9,CSDC2,GHR,DBF4,GPT2,ADAMTS6,GUCY1B1,IDH3B,IGF1,USP54,KCNK3,IPO5,TTYH2,LAMA2,NCOA7,CD200,SAMD5,FXYD6,NNAT,DDR2,PDGFRA,GNG2,SERPINE2,FTO,SMOX,PPP3CA,PTCH1,PTH1R,SPDL1,ROGDI,RDX,REV3L,UBR7,ROBO1,ROBO2,CCDC112,FAM192A,TNFRSF19,PUF60,DZIP1,NUBPL,WDR37,EPC1,SMARCC2,CDK5RAP2,PALLD,PDZRN3,SOX11,BEX1,ZC4H2,TMEM136,PSD3,TGFBR3,HHIP,DAAM2,BEX4,TPM2,SYNPO2,AMACR,STXBP4,VSNL1,TSPAN11,NSD2,ZIC3,PMEPA1,EVI5,TUBA1A,ADAMTS10" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_1000_K1 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 3.99E-05 2.04E-01 2.26E-04 2.06E-03 91 372 "EMILIN3,ACTN2,ADCY2,KIAA1324,SRPX,ARHGAP20,CDK10,DACT3,ADGRB2,ZNF599,C1QC,CACNA1G,LDLRAD4,CACNA2D1,RUNX1T1,REPS2,KCNAB3,CDO1,CRLF1,COL9A2,ABI3BP,ANKRD44,CRYM,CSF1R,CCDC3,DLG2,DRP2,DUSP9,ABCC9,RASA4,ELN,EPB41L1,LRRC17,EPS8,FCGRT,TRIM16,FYB1,ARPP21,TMEM8B,ZNF276,WIF1,SYNPO,IL11RA,VWA5A,GPR155,MITF,RSPO2,TCEAL5,NELL1,NFIA,NFIX,NPR2,CLEC9A,CNTN3,PDE4D,PLCL1,TRHDE,NXPH1,PRKAR1B,ACSS3,IQSEC3,ZCWPW1,ZNF493,ZMAT4,ZFHX4,MYH14,LRRK2,DGLUCY,ATXN1,MRAS,SH3GL3,ASAP3,DOCK10,SLC1A2,SLC6A9,SLC8A1,LIMCH1,ACSBG1,UNC5D,ADGRL3,SATB2,PHF24,FAM189A1,SYNPO2,TRPS1,TSPAN11,LAMP5,PMEPA1,CADM2,PCDH15,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k4 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.00E-05 2.04E-01 2.26E-04 2.06E-03 24 64 "SORCS1,PCDH10,RUNX1T1,SLC35F1,TENM4,ERC2,SCRN1,BRINP1,NTM,FOXF2,SGIP1,MEGF10,GABRB1,PCDH17,IFI16,KCNK2,GPR85,ZFHX4,SCN3A,NTNG1,ANKRD6,NPAS3,RPRM,FMN2" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 4.12E-05 2.10E-01 2.33E-04 2.12E-03 134 591 "ABAT,EMILIN3,PLEKHG5,RTL9,OSBPL8,SEMA6A,ANK1,CACHD1,CDK10,PDXK,IGDCC4,DACT3,RASL11B,BMPR1B,CACNA1G,CACNA2D1,RUNX1T1,LRBA,CRLF1,DIS3L,COL9A1,COL9A2,COL9A3,SLC4A7,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,BOC,ARHGAP24,GSDME,RHOBTB1,GRIN3A,DNM1,USP3,DUSP9,ABCC9,MBNL2,LRRC17,DENND4A,HSPA12B,FCGRT,TESK2,FECH,SCARA3,FOXF2,TRIM16,TMEM151A,TRAF3IP2,ZNF274,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,WIF1,SYNPO,IDH3B,IL11RA,INPP1,ITPKB,JAK2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,KITLG,CD200,RSPO2,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,PDE3A,PDE4D,PFKFB2,CDK14,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,CRLS1,LRRC49,CNTLN,IQSEC3,FAT4,RAP1GAP,BEND5,RGS10,ZFHX4,BAALC,ATXN1,SH3GL3,NTNG1,CNKSR2,DZIP1,SLC8A1,IFT122,LIMCH1,PDZRN3,CDK19,EPB41L3,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ASXL3,ANKRD24,PIK3R5,SYNPO2,TRPC3,TRPS1,RFTN2,TSPAN11,WIPF1,CLIP2,ZNF32,FTSJ1,ADAMTS10" Coexpression Atlas gudmap_RNAseq_e15.5_Podocytes_2500_K3 gudmap_RNAseq_e15.5_Podocytes_2500_K3 Gudmap RNAseq 4.16E-05 2.12E-01 2.35E-04 2.14E-03 27 76 "APLP1,CADPS,MYRF,CACNA2D2,CRMP1,FAM78B,MAMLD1,ERBB4,ERCC2,TUBB4A,CORO2B,AFF2,GAP43,GPM6A,GPM6B,RNF165,HPCA,SHISAL1,KCNH2,MEST,MDGA1,RETREG1,LRRTM4,NTNG1,SLIT1,ANKFN1,SYP" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.35E-05 2.22E-01 2.45E-04 2.24E-03 37 118 "KLHL13,NR0B1,LGR5,CDC14B,PPP4R4,IGDCC4,BOC,SRGAP3,TSPAN5,NRN1,IP6K2,AFF2,ZMAT1,GABRA4,TRAF3IP2,PCDH11X,KLHL23,MAP2,MATN2,NEXMIF,NFIA,PDE1A,PCDH18,PPP3CC,REV3L,TMEM206,LGR4,HUNK,ATF7IP,UHRF1BP1L,SMOC1,ST5,ADGRL3,OBSL1,ZFPM2,TRPS1,TST" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.52E-05 2.30E-01 2.55E-04 2.32E-03 44 149 "EMILIN3,USP31,ANK3,APC,BMP7,CDK5R1,CACNA1D,CACNA2D1,KALRN,CLIP3,VCAN,ELMO1,ARNT2,GRIN3A,DNM1,EDNRB,HIPK3,KIAA1109,IQGAP2,SYT17,GFRA1,PCDH17,PCDH11X,KIAA1958,GRIA2,KLF12,BACH2,MKLN1,NFIA,PDE3A,PRRX1,FAT3,KANSL1,REV3L,ZHX3,SMOC1,EPB41L3,CAMSAP2,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,NUP214" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_1000_k5 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.68E-05 2.39E-01 2.64E-04 2.40E-03 18 42 "AMPH,CRYM,SNAP91,EYA1,SCARA3,DPYSL4,TVP23A,FAM107A,HAS2,TAGLN3,FXYD6,NELL1,PRTG,CEP41,SALL1,ANKRD6,LRP8,NETO2" Coexpression Atlas PCBC_MESO-5_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_1000 PCBC 4.81E-05 2.45E-01 2.70E-04 2.46E-03 208 985 "KCNH8,EMILIN3,CSMD3,GALNT13,SORCS1,ERMN,PLEKHH1,ADORA1,PTCHD1,NLGN4X,NR0B1,C1QTNF1,C1QTNF4,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,APOC1,LGR5,ARSE,RASL11B,KIF1A,FGF17,BMP7,BTK,CASTOR3,C5,MYRF,MAP7,CCK,CCKBR,USP2,CDH8,L3MBTL4,PLEKHB1,DLGAP3,SLC24A2,FAM189A2,IGLON5,COL9A1,COL9A2,COL9A3,GAL3ST1,TCEAL2,NRG2,RIMS4,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,LONRF1,AIF1L,C8orf34,SV2B,KIF19,HS3ST4,CALN1,SLC25A18,DSCAM,FAM78B,USH1C,EFNA2,ELAVL4,ERBB4,TMEM74,RASL12,ADGRV1,PPP1R1B,MED12L,C1orf61,C2orf88,RASL10A,DACH2,B3GAT1,ADGRA1,TBR1,BRSK1,PHYHIPL,MEGF10,HRASLS5,GABRA5,GABRB3,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,TMEM121B,CECR2,GRIK3,PTPN5,TMEM179,FAM222A,HAS2,IGSF21,NXPH2,IGFBPL1,SHISA6,CELF5,NKD1,ZIC5,TUBB2B,ZNF385B,LRRTM1,C2CD4C,KCNF1,CLVS2,KCNJ3,KCNQ2,KIF5C,KIT,MATK,MATN3,SCG3,DDX25,MYL3,MYT1,NNAT,NODAL,NPPA,NRCAM,HCN1,IGSF11,OLR1,PAX6,PCDH8,PCSK2,PRTG,SEMA5B,A2ML1,JAKMIP1,HMGCLL1,NECAB2,MAGEL2,PACSIN1,RASGEF1B,RAB39A,SMIM10L2B,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,ACSS3,FAM184A,KHDRBS2,PRIMA1,LGI2,MRAP2,EMID1,SYNDIG1,RXRG,SALL1,SEMA6D,TMEM200C,SH3GL2,ANKRD6,SLC1A6,RCOR3,INAVA,SOX10,LHFPL4,BEX1,MCF2L2,SSTR2,AJAP1,ZFR2,TMEM150C,TAC3,KLHL4,FAM189A1,PCDHA6,PCDHA3,PCDHA2,LEFTY2,GALNT17,TMOD1,FAM124A,PIK3R5,SEZ6L,TRPM2,CA14,RPRM,CLEC2L,VIPR2,RBFOX3,PORCN,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,PLPP4,ANKS1B,CADM2,SHD,RGMA,XKR7,GAL3ST3,DOCK8,SLC4A10,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000_k2 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.82E-05 2.46E-01 2.71E-04 2.47E-03 12 22 "BACH1,ELAVL2,TUBB3,LPAR4,TUBB2B,KLC1,MAPT,NNAT,SNRPN,SOX2,ZIC1,PCBP4" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500_K1 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 4.91E-05 2.50E-01 2.75E-04 2.51E-03 43 145 "ERMN,TMEM108,CA4,CBLN1,INA,CLCN3,CLU,FAM169A,CHRDL1,ST8SIA3,PLEKHA1,SEZ6,PIPOX,REEP2,TUBB4A,JPH4,SALL3,GPD2,LPAR4,CECR2,HSP90AA1,CDH20,IPO5,MOBP,IGSF11,PRTG,PDE1A,SNX10,PKM,MAGEL2,GDPD2,PTPN13,SALL1,SNRPN,BEX1,PBLD,AJAP1,MTCL1,WASHC4,BEX4,ZIC2,ZBTB16,CA10" Coexpression Atlas GSM538268_500 "Myeloid Cells, DC.IIhilang+103+11blo.SLN, MHCIIhi CD11c+ Langerin+ CD103+ CD11b-, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.94E-05 2.52E-01 2.77E-04 2.53E-03 95 394 "CPNE2,FMNL2,DSCAML1,ADCY6,TMCC3,GRAMD1B,ADORA2A,SEMA7A,APP,SHTN1,ARHGAP5,CAPRIN2,ZBTB10,ATP2B1,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,CLU,STOML1,LY86,SLC4A8,ABCG1,CSF1,ATRNL1,PNPLA8,CTNND1,RASSF2,GUCD1,RABGAP1L,DNM1L,EFNA2,EBI3,PLXNC1,ENO2,MTSS1L,EXTL1,MEX3B,ZMYND15,NEK6,MTHFD2,RAB30,ADAP1,SLC2A6,GYG1,HSF2,IRF8,DOCK7,SCIN,INSM1,TUBB2B,KTN1,VWA5A,ASPRV1,ADAM11,NPR2,PBX1,PFKFB3,CDK14,SSH1,CCSER2,PLCL1,SLC22A23,EML5,PLEKHB2,ROGDI,ZDHHC14,RGS12,PRR5L,SEMA6D,SCN4B,ARHGEF40,CCDC88A,SAMSN1,ST5,STXBP1,TMEM150C,ARC,ATP11A,ATMIN,PHF24,PSD3,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,ZBTB38,EML6,SPIRE1,WNK1,ITM2C" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.97E-05 2.53E-01 2.78E-04 2.53E-03 38 123 "ADCY2,SPARCL1,ALCAM,ARHGAP20,GPAM,LRRC4C,CACNA1G,SLIT2,ATRNL1,VCAN,BOC,DNM1,EDNRA,EGFR,LRRC17,FLNC,GFRA2,FREM1,GUCY1A1,GUCY1B1,NKD1,MEIS1,NCAM1,NFIA,PCDH9,PDGFRA,PIK3R1,FXYD1,PCDH18,PRRX1,LAMA1,PTN,TMEM255A,MEG3,PALLD,PSD3,FLRT2,VSNL1" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k1 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.03E-05 2.56E-01 2.81E-04 2.56E-03 30 89 "FAM135A,CASK,RNF182,CDH2,NSL1,PYGO1,EBF1,EFNA3,ABI2,ADGRV1,UBE2E3,CHL1,HAS2,LSAMP,MYO5A,PBX1,PCDH8,ANLN,CNTLN,CRTAC1,FIGN,SALL1,NTNG1,DZIP1,WDR37,CXXC4,PCDHB3,ASXL3,MKRN3,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.03E-05 2.56E-01 2.81E-04 2.56E-03 30 89 "ARHGAP20,MYRF,REPS2,AKAP5,ZNF521,BOC,DPYSL2,TSPAN5,NSG1,TRAF3IP2,ELOVL5,IGF1,NKD1,MAP2,MATN2,MEIS1,CCDC80,LAYN,NFIA,NNAT,OPHN1,PDE1A,PCDH18,FAT4,TSPY26P,RNASEL,MEG3,CCDC112,SEMA6D,PEG10" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.03E-05 2.56E-01 2.81E-04 2.56E-03 30 89 "AMPH,EPB41L5,VAT1L,ZSCAN18,ATP1A2,CACNA2D1,FAM19A5,ZFP28,CRYM,SIPA1L1,ELAVL4,CDHR1,EYA1,ST3GAL6,FGFR1,SCARA3,MEGF10,FAM19A2,FAM107A,HAS2,JAKMIP3,FXYD6,NELL1,PRTG,CEP41,RPS6KA2,SALL1,ANKRD6,SLC1A3,HEY1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 5.16E-05 2.63E-01 2.87E-04 2.62E-03 62 233 "SPARCL1,CDC42BPA,MAP4K3,TMEM263,DOCK11,CD81,CDH2,CHN1,NRXN1,CNN3,ARHGEF6,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,TUBB4A,DLC1,SGIP1,DKK3,DENND2A,HIGD1B,GNAS,FERMT2,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,PRKAR1B,C1orf54,RGS4,PRR5L,EMID1,HUNK,PEAR1,BTBD3,SMTN,PDZD2,SOX5,MYCBP2,DBNDD2,CLSTN2,SSTR2,ST5,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k4_500 kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.61E-05 2.86E-01 3.12E-04 2.85E-03 54 196 "RNF157,AMPH,BCL7A,BMP7,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,PHF19,GSDME,SNAP91,DTNA,EDNRA,ELAVL4,KCNMB2,ETV1,RRAGB,EYA1,FGFR1,MAD2L2,SCARA3,IGSF5,GFRA1,FREM1,CECR2,CNTRL,FAM107A,HAS2,NEGR1,MEST,NCAM1,NELL1,NME4,CNTN3,FAT3,MDGA2,TSPY26P,TMEM100,SALL1,FAM19A1,SLC1A3,SLC4A3,GKAP1,ADAMTS17,CUX2,PCDHB9,TMOD1,CADM1,SLC38A1" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 5.78E-05 2.95E-01 3.22E-04 2.93E-03 41 137 "LGR5,CACNA1D,CALB1,ATRNL1,PLXNA4,DOCK4,MAGI2,SRGAP3,DRP2,EDNRA,PLXNC1,EMX2,LRRC17,NRN1,AFF2,GABRA4,GABRB1,GATM,FREM1,PCDH11X,GUCY1A1,PLD5,KCND2,KLHL23,MATN2,MEIS1,KITLG,NFIA,PDE1A,PDGFRA,PCDH18,TMEM206,LGR4,KDM3A,SMOC1,ADGRL3,TEX15,ZFPM2,ACTR6,FNDC5,LYPD6" Coexpression Atlas gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_1000 dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.85E-05 2.99E-01 3.25E-04 2.96E-03 52 187 "TKTL1,AXIN2,BRAP,ESYT2,HACE1,HFM1,MADD,PLA2G4C,CCDC181,ZNF583,LRBA,LONRF2,KMT2C,ZFYVE9,C4orf33,DZIP3,FBXO25,RABGAP1L,DUSP9,ATL1,DENND4A,KIAA1109,PRKAG2,GRK4,COQ10A,ADAM22,MYO9A,NEK1,PRTG,PDE3B,PENK,EML5,ZCWPW1,CARF,CCDC25,ACER3,STX1B,FNIP1,KIF27,SH3BGR,MAGI3,CNKSR2,CCDC92,DOP1A,EPB41L3,ZSCAN29,VPS13A,TEX15,TRPC1,UGT8,SLAIN1,SLC30A4" Coexpression Atlas GSM538266_500 "Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2" "Immgen.org, GSE15907" 6.09E-05 3.10E-01 3.38E-04 3.08E-03 91 376 "RNF150,PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,ATP1A3,CADM3,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,ZNF385A,CSF1R,CSF2RA,CST3,SDC3,CTNND2,USP6NL,CYBB,DOCK4,HDAC9,MYADM,SIRPA,DSCAM,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FGR,GATM,GCNT2,MALT1,RAB30,ADAP1,ZNF496,GSN,FRMD5,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KIT,LIFR,ADAM11,MEF2C,STK32C,ADAM22,MYO5A,CLEC9A,CDK14,ABCB1,PLTP,RASGEF1B,MARCH1,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SCN3A,ST8SIA1,SLC8A2,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,KIAA0930,DDHD1,TNS1,NPL,TRIO,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500 facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500 Gudmap RNAseq 6.17E-05 3.15E-01 3.42E-04 3.12E-03 274 1349 "ABCF1,AXIN2,PLEKHH1,KIAA1324,MYH7B,CNIH2,EPB41L5,UPRT,VAT1L,BCAS1,CPNE5,ARHGDIG,ATM,KIF1A,DOCK11,BACH1,ADGRB2,BCHE,NRP2,BLM,ZNF599,PROM1,FUBP1,OSGIN2,WASF1,CA4,CA12,PTBP2,CAMK2A,BRSK2,MAP7,CCNT1,CDK11B,CDH2,CIART,JAM2,ARHGAP22,NRXN3,KIAA1549L,FAM19A5,C4orf33,QKI,CNTFR,IQCK,BAG4,IGDCC3,CHD1L,NECTIN3,SLC35F1,FAM171B,CRMP1,FEZ1,LRRC3B,FAM169A,PPP1R16B,CTH,GREB1,CFAP61,CTNND2,KATNAL2,RASSF2,TOMM20,SIRPA,DDX46,SHANK1,CASP8AP2,E2F5,AASDH,EDN1,EFNA2,EFNB3,LPAR6,EIF5,ELAVL2,PLEKHA1,CERCAM,ELAVL4,EPHB1,EPS8,RTN3,CEND1,ADGRV1,CD320,REEP2,FABP7,TBC1D16,TUBB4A,CORO2B,ST3GAL6,CEP78,PRMT5,POLR1B,SPSB4,FGF12,BAIAP2,FHL1,ZMYND15,NOP56,COQ5,ZCCHC17,CINP,SMC2,FAM49B,USP21,PRELID3A,GPR153,FUT9,PHYHIPL,MTHFD2,GART,WASF3,GATM,RUNDC3A,GK,RND1,TCERG1,GLDC,DBF4,GLI2,TOX3,CBX1,KIAA1958,KDM2B,GNG3,GPM6A,CCDC184,GPR19,LPAR4,CECR2,STMN2,RNF165,MFSD2A,PSIP1,FAM222A,CELF3,TOX2,FRMD5,HSF2,HSP90AA1,SHISAL1,NKD1,LRRCC1,LIX1,LRRTM3,SLC35G1,KCNK1,KIF2A,IPO5,KTN1,CAMK2N2,HECTD2,MAP6,MAT2A,AQP11,ADAM11,AFF1,MN1,SAMD5,MSI1,MYCN,NAP1L1,NASP,RCOR2,CNOT4,NOVA2,PCBP3,NRCAM,NTRK3,ODF2,PDCD2,PDE3B,ENPP2,FAM98B,OLA1,PFKP,NLGN3,SEMA5B,PKM,PLP1,SLC25A23,PLTP,PSAT1,POLR2F,PPP1R1A,PTPA,MAPK4,PRODH,PROX1,RELN,LAMA1,GDPD2,ELOVL2,SPDL1,PTN,PTPN13,EML5,NKAIN1,CCDC40,ERI2,FIGN,RNF220,NUDT11,RPL15,ACER3,RTN1,SALL1,LRRTM4,SCN8A,TNFRSF19,ELMOD1,ZFP2,HSPA4L,SCG5,PPM1E,NTNG1,FHOD3,CCDC92,ANKRD6,NUBPL,PKNOX2,SLC20A2,SLIT1,RIMS1,ANKFN1,SOX2,SOX11,ZNF423,ZC3H13,BEX1,RBM26,PBLD,LARP4,MTCL1,MCF2L,WWC1,WSCD1,SIRT1,C18orf54,ITGB3BP,BEX4,TNFRSF1B,NPL,PRMT8,CA14,TST,CADM1,RPRM,SLAIN1,FAM181B,USP1,NSD2,XPO1,CFAP298,KCNT2,ZFP41,SLC26A10,ZBTB16,ZNF184,DPYSL5,SMARCAD1,MEIS3,SLC38A1,RGMA,TUBA1A,NAV2,PCBP4,WNK3,AMN1,FZD3,MRPL47,VANGL2,AAAS,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 6.19E-05 3.15E-01 3.43E-04 3.12E-03 53 192 "CPNE2,KLHL32,ADCYAP1R1,PROM1,PTBP2,CANX,CDK11B,JAM2,KIAA1549L,NIPBL,IQCK,SLC4A7,SLC4A8,IGDCC3,KATNAL2,JAKMIP2,DDX46,CASP8AP2,MAMLD1,RTN3,NSRP1,FGFR3,ILDR2,KIAA1841,TCERG1,MAP7D2,CIT,USP51,KIF5C,KTN1,RSPO2,NASP,NEFM,NOVA1,NTRK2,ODF2,GPR137C,FAM98B,SEMA5B,ELOVL2,EML5,ARID4A,CLIP1,SAFB,NLGN1,GKAP1,BDP1,NEK4,SYNE2,SYN1,CCDC173,ZNF23,FMN2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.38E-05 3.25E-01 3.53E-04 3.21E-03 78 312 "ADCY2,RNF150,ARHGAP20,LRRC4C,RASL11B,TMEM108,MYRF,KALRN,CBLN1,CDH10,SLIT2,CNTFR,AKAP5,CLIP3,TENM4,MICAL2,ATRNL1,VCAN,TIAM2,SV2A,DNM1,EDNRA,SEMA3D,EGFR,C8orf37,F3,FABP7,TUBB4A,CAP2,FLNC,NSG1,GABRA1,TRAF3IP2,DENND2A,FREM1,CSDC2,GHR,GLI2,GUCY1A2,GUCY1A1,HAS2,TCEAL6,NKD1,MAP2,MATN2,MEIS1,TCEAL5,NCAM1,ZC3H12B,NEFM,NME4,PDGFRA,PIK3R1,PCDH18,PRRX1,SYTL2,LAMA1,PTN,PTX3,RADX,ROBO2,MEG3,PKNOX2,PALLD,ZCCHC24,SULF2,KLHL7,PSD3,ASXL3,HEY2,TPM1,TRPS1,SSBP2,TMEFF2,PLEKHH2,ZFP37,STOX2,ST8SIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.61E-05 3.37E-01 3.65E-04 3.33E-03 29 86 "USP31,PCDH10,DPP10,NRP2,CACNA1B,CDH10,CRHBP,VCAN,PLCXD3,GRIN3A,CALN1,GABRB1,GFRA1,GFRA2,PCDH17,IFI16,KIF5C,RSPO2,NDP,CLDN11,PRPH,REV3L,ZFHX4,SLC15A2,SOX2,C11orf87,EPB41L3,CUX2,RBFOX2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 6.73E-05 3.43E-01 3.72E-04 3.39E-03 134 597 "EMILIN3,RTL9,SRPX,ANK1,KCNAB2,CACHD1,CDK10,PDXK,IGDCC4,SPTBN4,RASL11B,CACNA1G,GPC2,RUNX1T1,LRBA,CDO1,CRLF1,COL9A2,COL9A3,ABI3BP,ANKRD44,SNCAIP,ARHGAP24,DGKG,C8orf34,RHOBTB1,GRIN3A,DNM1,ABCC9,HEYL,MBNL2,ELN,HSD17B14,EPB41,EPB41L1,LRRC17,DENND4A,HSPA12B,FCGRT,TESK2,SCARA3,FOXF2,SGIP1,TRIM16,STAU2,TVP23A,ZMAT1,DKK3,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GSN,WIF1,SYNPO,ICA1,LRRCC1,IL11RA,INPP1,JAK2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,ADAM11,SRSF12,RSPO2,TCEAL5,FXYD7,NFIX,NPY,CLEC9A,NRGN,ZNF827,CNTN3,PDE3A,PDE4D,PIRT,PFKFB2,SERPINE2,FTO,PRRX1,SDK2,EPB41L4B,CCDC144B,DIRAS2,PRODH,CNTLN,PTPRE,IQSEC3,RAP1GAP,BEND5,MORC4,ZFHX4,MRAP2,BAALC,SOX8,DGLUCY,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,SMARCC2,PDZRN3,BDP1,CDK19,EPB41L3,NKAIN2,ARHGEF9,PLCB1,TACR1,KAZN,TBX15,TCF4,SATB2,SYNE1,PHF24,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRPS1,RFTN2,ZNF32,PMEPA1,NAV3,CERS6,SSPN" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000 DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.94E-05 3.54E-01 3.83E-04 3.49E-03 176 819 "TTYH1,ABCF1,ACLY,NCKAP5,TKTL1,ACTN2,ARID1A,DSCAML1,ADD1,AP2A2,AGT,TBC1D14,NR0B1,KIAA1324,SORCS2,AK2,TAOK1,C1QTNF3,ARHGAP20,LTBP4,AMH,OGT,SEMA7A,DGKD,ARHGDIG,ARRB2,DDX3Y,BACH1,ST3GAL5,PRMT9,MMD2,BTRC,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,SCARB1,CDC42,ADGRG1,CLU,FADS2,NIPBL,COL9A3,RBM39,RNF14,SNCAIP,CTNND1,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,PLPPR4,SACS,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELAVL2,ELN,EPB41L2,LRRC17,ENPP6,NRN1,PTK2B,SCML2,FGFR1,BAIAP2,FYN,GATM,AHDC1,MAP7D2,OS9,GPM6B,LPAR4,GPR37,GRB10,SPACA9,GUCY1B1,MAEL,HSD17B1,IL6ST,TUBB2B,JAK1,KCNH1,KCNK3,KIF2A,KLC1,TTYH2,MAPT,MDFI,CHIC1,MEF2C,DDX25,MTR,MYH6,MYO7A,NEXMIF,NCAM1,NEFH,NFIA,NFIX,NNAT,PAK3,PC,PDGFRA,SERPINI1,SEMA5B,PIK3CD,PLEC,FXYD1,PCDH18,RC3H2,EXOSC10,FSD1,PRKACB,MAPK3,BCAS3,PTPRE,MRPS18A,TMEM206,MEG3,SEC14L1,SFPQ,ARX,SLC1A6,EFHD1,SMARCA4,SNRPN,SON,ZCCHC24,ENKUR,SPP1,RBM26,SPART,TROVE2,SULF2,ACSBG1,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,OBSL1,PUM2,TEX15,LEFTY2,HHIP,TMPO,TNS1,RBFOX2,TPM1,NR2C2,TST,UBTF,UCHL1,USP1,ZNF142,ZFAND5,INTS3,PMEPA1,STOX2,ADAMTS9,VPS35L,PCBP4,RTN4,VANGL2,ADAMTS10" Coexpression Atlas PCBC_ratio_SC_vs_DE_100 ratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_100 PCBC 7.26E-05 3.70E-01 4.00E-04 3.64E-03 32 99 "UNC5A,ATP1A3,LDHD,RAB33A,PHYHIP,LINC00599,RASGRP2,SEZ6,ANKRD13B,CEND1,ACTL6B,HPCAL4,JPH4,SOX21,HRH3,BTBD17,NPTX1,ZDHHC22,PAH,CAMKV,GDPD2,TMEM145,SCN4B,BCAN,LRRC55,SOX21-AS1,ACSBG1,RHBDL3,ARC,TMEM151B,TLL2,SLC30A3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.27E-05 3.71E-01 4.00E-04 3.64E-03 80 323 "ABR,ADD3,AP2A2,ALCAM,LRCH2,ADGRB2,MYRF,ISPD,CDH2,MAGI1,RCBTB2,ZBED5,SLIT2,NMT2,CREM,HAPLN1,BRINP1,DDX46,AK5,FARSB,EDIL3,WDPCP,SEMA3D,STARD3NL,EPHB1,CORO2B,FLT1,SPECC1,PNMA2,GAB1,GABRA3,GABRB3,JPH4,NEK6,PCDH11X,LOXL3,GPT2,GPM6B,FUT10,B4GALNT4,GPR37,GRIN2C,RASSF8,ARHGAP19,ITGAV,MEIS2,SAMD5,MYO6,HNRNPM,NASP,OPA1,PDE1A,PCDH18,MAGEL2,GRAMD1C,LRRC49,GON4L,LRFN5,ELMOD1,ASRGL1,SLC1A6,SEPHS1,SPHKAP,SNCA,UNC5B,SPART,C11orf87,THSD1,NEK4,HIF3A,ZFPM2,ITGB3BP,THBS4,RBFOX2,TRO,TMEFF2,PLPPR5,INTS3,STOX2,NETO1" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.32E-05 3.74E-01 4.02E-04 3.67E-03 48 170 "SEMA7A,APOC1,CDC14B,ARHGDIG,RGS11,DST,ST3GAL5,RGN,ADGRG1,GPRASP1,DBI,CPEB2,DTNB,SIDT2,PLXNC1,SORBS3,CERCAM,EPS8,AFF2,CAMKK2,ZMAT1,GART,GPR37,SHISA6,LRRTM3,KCNH1,SYTL4,NCOA7,MOV10,CTNNA3,ETFRF1,PEX2,SH3TC2,TMEM206,RPS6KA2,ATXN2,MRAS,FRMPD1,ST8SIA1,SLC1A6,SOX5,TSPYL2,SMOC1,FGD4,OBSL1,TST,ADAMTS9,WNK3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.50E-05 3.82E-01 4.12E-04 3.75E-03 46 161 "NR0B1,ARHGAP20,MYRF,CALB1,CBLN1,CDH10,DCLK1,CNTFR,HAPLN1,ATRNL1,VCAN,PLXNA4,DOCK4,DRP2,EDNRA,PLXNC1,EMX2,GABRA4,FREM1,PCDH11X,GUCY1A1,NKD1,KCND2,KLHL23,MATN2,MEIS1,CCDC80,NCAM1,NEFM,NFIA,PDE1A,PDGFRA,PCDH18,PRRX1,PTN,TMEM255A,LGR4,UHRF1BP1L,ADGRL3,KLHL4,ZFPM2,ACTR6,ASXL3,DAAM2,PCDH20,DPF3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.60E-05 3.88E-01 4.17E-04 3.80E-03 44 152 "KLHL13,NR0B1,LRRC4C,CALB1,ATRNL1,PLXNA4,DOCK4,MAGI2,DRP2,EDNRA,PLXNC1,EMX2,NRN1,FLNC,GABRA4,GABRB1,FREM1,PCDH11X,GUCY1A1,NKD1,KCND2,KLHL23,MATN2,MEIS1,KITLG,CCDC80,MYO9A,NEFM,PDE1A,PDGFRA,PCDH18,TMEM255A,TMEM206,LGR4,SLC4A3,KDM3A,SMOC1,ADGRL3,TEX15,ZFPM2,ACTR6,DAAM2,LYPD6,WNK3" Coexpression Atlas Arv_EB-LF_2500_K4 AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 7.77E-05 3.96E-01 4.26E-04 3.88E-03 75 299 "ERMN,NLGN4X,SYT13,PDZD4,KIF1A,CALB2,BRSK2,CHGA,CHGB,SYNPR,FAM19A5,IGLON5,TCEAL2,LRRC3B,RIMS4,CNTNAP2,RIMS3,BRINP1,FAM57B,LINC00599,BSCL2,SEZ6,ADGRV1,F5,FABP7,FGF1,FOXG1,CSPG5,B3GAT1,TMEM151A,TVP23A,DKK3,MEGF10,GABRA3,GABRA5,GFAP,GRIA4,HP,CELF5,BTBD17,FAM95B1,KIAA1755,PLD5,BRINP3,KCNA6,KCND2,KCND3,KCNK3,KCNQ2,KIF5A,KIF5C,C2orf80,SCG3,MYH6,TCEAL5,NPPA,SEMA5B,FAT3,PPP2R2B,GDPD2,PTPRZ1,SYNDIG1,TMEM200C,SLITRK3,TMEM132D,SLN,NMNAT2,SPP1,ZFR2,SYT1,KCNT2,REEP1,SHD,GAL3ST3,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_200_k5 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.81E-05 3.99E-01 4.28E-04 3.90E-03 9 14 "VAT1L,CACNA2D1,SNCAIP,CDHR1,SGIP1,DACH2,MEGF10,NEGR1,NEK4" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_200 DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 8.04E-05 4.10E-01 4.40E-04 4.01E-03 47 166 "ADD1,PNMA8B,ARHGAP20,LTBP4,PKP4,DDX3Y,ATP2B1,BACH1,VSTM2A,RUNX1T1,DCLK1,CHM,SLIT2,COL4A5,RBM39,RIPOR2,ZC3H11A,EDNRA,EIF4G1,ELN,EPB41L2,LRRC17,GABRB1,GAD1,GLUL,LPAR4,GRM7,CHIC1,MEIS1,MEIS2,MMP16,NFIX,PCDH9,PENK,NALCN,FAT3,C1orf54,LGI2,TMLHE,MEG3,ARX,SYNE2,CBX5,SSBP2,UBE3A,FLRT2,ADAMTS9" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_k4_1000 kidney_adult_RenCorpuscGlomer_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.31E-05 4.24E-01 4.54E-04 4.13E-03 43 148 "CPNE2,APBB2,PDE8B,DDX3Y,CACNA2D1,ARHGEF6,CP,KIAA0040,DGKB,ZEB2,EBF1,FRY,RCAN2,RASGRP2,RAPGEF4,GUCY1A2,GUCY1A1,GUCY1B1,FRMD3,INPP5B,CCDC80,LAYN,NCF2,PDE3A,PDGFRA,SERPINE2,SERPINI1,PIK3R1,PLCL1,SEPT4,PKIA,PTN,ZDHHC14,ZMAT4,DOCK10,PREX2,SLC12A2,ITPRID2,RGL1,PSD3,TLR4,TRPC1,TMEFF2" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k2_500 kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.33E-05 4.25E-01 4.54E-04 4.14E-03 53 194 "ABR,RNF157,AMPH,VAT1L,SEMA4G,CACNA2D1,CACNB4,CDH2,CNTFR,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,PHF19,GSDME,SNAP91,DTNA,ELAVL4,KCNMB2,ETV1,EYA1,FGFR1,SCARA3,CAP2,IGSF5,GFRA1,FREM1,TDRKH,CECR2,FAM107A,HAS2,NEGR1,MEST,NCAM1,NELL1,NME4,CNTN3,PRTG,SMOX,FAT3,MDGA2,TMEM100,HUNK,SALL1,SLC1A3,SLC4A3,NUDT10,ADAMTS17,CUX2,CADM1,LAMP5,SIGLEC10" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_100 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.37E-05 4.27E-01 4.56E-04 4.16E-03 29 87 "C1QTNF3,DPP10,IL33,CACNA2D1,SEMA3D,TMTC1,GABRA1,CHL1,GLRB,GRIA1,GRIA4,GRM3,RASSF8,IFI16,KCND2,NOVA1,PCDH8,RELN,SALL1,CSRNP3,SCN3A,SCN7A,FAM19A1,ST8SIA1,SLCO1A2,NEK4,PCDHB9,ASXL3,PCDH20" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_1000_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.49E-05 4.33E-01 4.62E-04 4.21E-03 36 117 "TMCC3,JAZF1,CRLF1,ABI3BP,TENM4,GSDME,G3BP2,SLC12A6,PLXNC1,ELAVL2,EZH1,FOXO3,B3GAT1,ILDR2,GATM,KIF3A,SHISA6,KIT,SYTL4,RSPO2,NOS1,ABCB1,MAPK10,GDPD1,PCMTD2,SATB1,KIF16B,CPEB3,SLC14A1,CLSTN2,SYNE2,ANKRD12,CAMTA1,TBC1D15,NDRG4,WNK1" Coexpression Atlas GSM476663_100 "Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1" "Immgen.org, GSE15907" 8.69E-05 4.43E-01 4.73E-04 4.31E-03 28 83 "CPNE2,ADGRG1,FADS2,GDA,CTNND1,CYBB,ARHGAP32,DGKG,PLXNC1,EYA1,MED12L,GCNT2,GRB10,GUCY1A1,HLF,ICA1,DOCK7,KIT,LMO2,MEIS1,MYCN,OCRL,PBX1,ITSN1,TET1,TEK,TIE1,TNS1" Coexpression Atlas GSM399394_500 "alpha beta T cells, T.DP69+.Th, 4+ 8+ TCRlo/int 69+, Thymus, avg-3" "Immgen.org, GSE15907" 8.80E-05 4.49E-01 4.78E-04 4.36E-03 76 305 "ADCY6,AXIN2,GRAMD1B,ARHGAP20,PITPNM2,DGKZ,DGKD,ALS2,ARNTL,RASL11B,ALDH7A1,CLDN10,METTL6,FMNL3,CBARP,CNN3,LRIG1,CSNK1E,PPP1R16B,TOX,DNAJC6,DLG4,RASGRP1,LPAR6,TNK2,TMEM35A,KIAA1109,FGF13,MEX3B,CAP2,IP6K2,TACC2,TMEM107,NSG2,FYN,CHL1,RAPGEF6,KDM2B,KCNMB4,DCLK2,GSN,ADAMTS6,TOX2,BACH2,IL6ST,ITPKB,HECTD2,AQP11,ZNF827,PDE4D,PACSIN1,SYTL2,BEND5,RGS10,RAVER2,SATB1,IL17RB,HSPA4L,SH3BP2,FAM102A,PPM1E,ST6GAL1,ST8SIA1,DZIP1,TET1,TNIK,VAMP1,SLC37A2,TCF7,TMOD1,TNS1,TRIO,TTC3,PMEPA1,MAP3K12,MVB12B" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 8.89E-05 4.53E-01 4.82E-04 4.40E-03 68 266 "SPARCL1,CDC42BPA,MAP4K3,CD81,CDH2,CDO1,CHN1,NRXN1,STOML1,ABCG2,CNN3,ARHGEF6,PNKD,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,VPS26C,RASL12,TUBB4A,DLC1,SGIP1,NOP56,DKK3,DENND2A,HIGD1B,GNAS,FERMT2,GUCY1A1,GUCY1B1,MIER3,KCNK3,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,PRKAR1B,C1orf54,RGS4,PRR5L,EMID1,HUNK,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,CLSTN2,SSTR2,ST5,TUBB2A,CADM1,VSNL1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-OSKM - NLT_cfr-2X-p05 Ectoderm Differentiated Cells-reprogram_NA_vs_Ectoderm Differentiated Cells-reprogram_OSKM - NLT-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 8.97E-05 4.57E-01 4.86E-04 4.43E-03 27 79 "ADORA1,PCDH10,RASL11B,LARGE1,COL11A2,NRG2,TENM4,LYPD1,EDIL3,EDNRA,TMEM132C,ITPKB,KCNA1,KIT,CLEC18A,SAMD5,PDE2A,IRX1,ZFHX4-AS1,LRRN3,RELN,ZFHX4,SLC30A10,SLIT1,TAC1,TMEFF2,DOCK8" Coexpression Atlas GSM605811_500 "gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3" "Immgen.org, GSE15907" 8.97E-05 4.58E-01 4.86E-04 4.43E-03 96 405 "ABR,GRAMD1B,MTA3,APLP1,BAIAP3,HIP1R,CD38,NUMBL,ADGRG1,CHN2,OSBPL3,IPCEF1,SIPA1L1,PPP1R16B,TOX,PITPNC1,DNAJC6,SRGAP3,RABGAP1L,ARRDC4,FAM135B,HEYL,RASGRP1,EPB41,DENND4A,EZH1,PTK2B,FDFT1,FGR,FOXO3,HVCN1,FYN,ATP8A2,IGSF5,GCNT2,HPGDS,OS9,GPD2,B4GALNT4,GPR34,PTPN5,PADI2,FRMD5,ACOT7,HMGCR,CFAP126,AGFG1,SCIN,ITGAV,ITPKB,KIT,STXBP5,HECTD2,SESN3,STK32C,MYO6,NEFH,NRCAM,P2RX7,ZNF827,PDE3B,ABCB1,PIK3R1,PLTP,SEPT4,PPP2R2C,PPP3CC,PRKACB,SYTL2,SUSD4,ZMAT4,WLS,ATXN1,MRAS,FAM102A,CLSTN1,ELMO2,PDZD2,TNIK,SP4,SPP1,TEX2,SULF2,ACSBG1,TCF7,FRYL,C18orf54,TNFRSF1B,PRRT1,TRIO,RUNDC3B,VIPR2,LAT2,ZBTB38,PMEPA1,MVB12B" Coexpression Atlas PCBC_EB_100 Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_100 PCBC 9.01E-05 4.60E-01 4.87E-04 4.44E-03 32 100 "LHX2,IGLON5,COL9A1,ELAVL3,ELAVL4,FABP7,ZIC4,NSG2,PHYHIPL,GPM6A,STMN2,CELF3,SCRG1,INSM1,KCNQ2,RSPO2,NELL1,NTRK2,PENK,GDAP1L1,POU3F2,NKAIN4,PRPH,RFX4,SST,SYT4,TAC1,CNTN2,TF,ZIC1,CRB2,STMN4" Coexpression Atlas Facebase_ST1_e10.5_NeuroEpith_MedialEmin_500_2 e10.5_NeuroEpith_MedialEmin_top-relative-expression-ranked_500_2 FaceBase_ST1 9.04E-05 4.61E-01 4.88E-04 4.45E-03 63 242 "PCDH19,NR0B1,PITPNM2,APBA2,SNAI3-AS1,CBLN1,USP2,INA,CDC25B,RAB33A,NMT2,FAM189A2,FAM19A5,FEZ1,JAKMIP2,COPS7A,PHF20L1,ING4,PCOLCE2,DENND4A,REEP2,SPSB4,DPYSL4,CELF1,TPPP3,PHYHIPL,NEU3,TOX3,PCSK1N,PRRC2B,SOX21,UBE2QL1,IGSF21,TOX2,NKD1,TUBB2B,LMO1,MEIS1,AFF1,MT3,MYO9A,PAK3,PALM,PAX6,PCDH9,SLC25A23,FAT3,ANKHD1,ELOVL2,FEZF2,PBRM1,ROM1,ARMH4,TNFRSF19,HSPA4L,CCDC88A,SEPT3,SYT11,WSCD1,TCF12,TMEM121,RBFOX3,ZBTB16" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K1 facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K1 Gudmap RNAseq 9.11E-05 4.65E-01 4.92E-04 4.48E-03 49 176 "ABAT,C1QTNF1,NRP2,UBE2L6,ARHGEF6,DGKB,ZNF804A,EBF1,EDN1,HEYL,TLR7,RASL12,FCGRT,KHDRBS3,TPPP3,HIGD1B,GDF9,LOXL3,GRM7,GUCY1A1,GUCY1B1,HLF,IFI16,IL6R,IL11RA,KCND3,CCDC80,MX1,NRGN,PDE1A,PDGFRA,SERPINE2,PLCB2,PLCL1,FXYD1,PTN,ZMAT4,RGS4,DOCK10,ZCCHC24,NKAIN2,TNS2,TLR4,DAAM2,TNFRSF1B,TMEFF2,PLSCR4,FAM13C,SSPN" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_500 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.13E-05 4.66E-01 4.92E-04 4.49E-03 22 59 "KLHL13,NR0B1,PPP4R4,PLXNA4,DCT,EMX2,AFF2,GABRA4,TRAF3IP2,PCDH11X,KLHL23,MATN2,NFIA,PDE1A,REV3L,LGR4,SMOC1,ST5,ADGRL3,OBSL1,ZFPM2,WNK3" Coexpression Atlas GSM605837_500 "Myeloid Cells, DC.8-4-11b-.Sp, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Spleen, avg-2" "Immgen.org, GSE15907" 9.18E-05 4.68E-01 4.94E-04 4.51E-03 90 375 "FMNL2,PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,ATP1A3,CADM3,ADAM23,ST3GAL5,CACNA1E,DDR1,CD86,CHN2,B4GALT6,LY86,CSF1R,CST3,SDC3,CTNND2,USP6NL,CX3CR1,CYBB,DOCK4,HDAC9,MYADM,SIRPA,SRGAP3,DSCAM,ARRDC4,PLXNC1,RASA4,PLEKHA1,EPS8,IGSF6,TLR7,SIRPB1,OLFM1,FGFR1,FGR,GATM,GCNT2,RAB30,GPM6B,ADAP1,GSN,FRMD5,IRF8,LRRC25,DOCK7,JAK2,KIT,L1CAM,LIFR,ADAM11,MEF2C,MRPL42,STK32C,MYO5A,MYO9A,CLEC9A,CDK14,RASGEF1B,PTK2,MARCH1,PID1,C1orf54,ROGDI,RGS12,SNX22,LRRK2,KCNIP3,RTN1,SCN3A,ST8SIA1,SLC8A1,CCDC88A,RGL1,SULF2,ADGRL3,KIAA0930,TF,TPD52,NPL,TRIO,TRPM2,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k3 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.32E-05 4.75E-01 5.01E-04 4.57E-03 23 63 "CADPS,ATP2B1,CNTN1,CNRIP1,ZEB2,EPB41L2,MRVI1,DACH2,GPM6B,HAS2,NEGR1,KCND3,LAMA2,MEIS1,MMP16,CLDN11,PRRX1,PTX3,SCN3A,VWC2,ZFPM2,TPM2,SYNPO2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 9.78E-05 4.99E-01 5.26E-04 4.79E-03 18 44 "CALB1,PLXNA4,DOCK4,DRP2,EMX2,GABRA4,PCDH11X,KCND2,KLHL23,MATN2,NFIA,PDE1A,PCDH18,LGR4,ADGRL3,ZFPM2,ACTR6,FNDC5" Coexpression Atlas gudmap_developingGonad_e16.5_testes_1000_k5 DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.83E-05 5.01E-01 5.27E-04 4.81E-03 57 214 "TTYH1,AGT,NR0B1,SORCS2,C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,MMD2,CBLN1,ADGRG1,CLU,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,FYN,GATM,GPM6B,GPR37,HSD17B1,IL6ST,JAK1,TTYH2,MEF2C,MYO7A,NFIA,NFIX,PAK3,PDGFRA,SEMA5B,PLEC,FXYD1,PTPRE,TMEM206,MEG3,SLC1A6,EFHD1,SPP1,SULF2,ACSBG1,TBL1X,SIN3B,HHIP,TNS1,NR2C2,TST,UBTF,PMEPA1" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k4 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.93E-05 5.07E-01 5.33E-04 4.86E-03 77 311 "ASIC2,PCDH19,TRMT9B,AMPH,VAT1L,ASTN1,DYNLL1,EIF4G3,BLM,OSGIN2,CACNA2D1,CALB1,KALRN,CDH2,CHGB,ZFP28,NSL1,CRMP1,CRYM,SNCAIP,RIMS2,SCRN1,BRINP1,PITPNC1,ARNT2,RAB39B,DUSP9,HEYL,EEF1D,EYA1,MED12L,SPSB4,SCARA3,TRIM16,RASL10A,DENND2A,BRD8,KIAA1958,ADGRA3,B4GALNT4,FAM19A2,HAS2,DHX35,LIG4,FXYD6,NASP,NPTX1,OXTR,CNTN3,PCDH8,PRTG,PDE1C,CEP41,GON4L,PPP2R3C,GAL3ST4,CRTAC1,PRR5L,EMID1,SALL1,SLC30A10,ASRGL1,ANKRD6,SLC9A5,C11orf87,ANKRD28,CAMTA1,ZFP90,AKNA,HEY1,TP53BP1,STXBP4,ZNF184,INTS3,LRP8,MRPL47,NETO2" Coexpression Atlas gudmap_developingGonad_P2_testes_1000 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.94E-05 5.07E-01 5.33E-04 4.86E-03 175 819 "TTYH1,ACLY,EMILIN3,TKTL1,ARID1A,TMCC3,ADCYAP1R1,ADD1,ADORA1,MTUS1,AGT,NR0B1,SORCS2,AK2,C1QTNF3,LTBP4,AMH,OGT,SEMA7A,DGKD,NT5C3B,ARHGDIG,ARRB2,MARK4,DDX3Y,ATP1A2,BACH1,DST,ST3GAL5,MMD2,BTRC,DDR1,CALM1,CAMK2D,CAMK2G,VXN,MAP7,CBLN1,ARHGEF1,SCARB1,CDC42,ADGRG1,JAM2,CLU,CLTB,FADS2,NIPBL,CABP1,CP,PNKD,RBM39,RNF14,RASGEF1C,ARHGEF4,CTNND1,PUM1,ARHGAP32,TOX,SCRN1,DAPK3,SPOCK2,DBI,DBN1,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,RASL12,REEP2,WAC,TUBB3,SCML2,FGF13,FGFR1,DPYSL4,CAMKK2,TPPP3,FYN,GATM,CSDC2,SPIN1,GPM6B,LPAR4,GPR37,GRB10,MAEL,HSD17B1,IL6ST,TUBB2B,ITPKA,JAK1,KIF2A,KLC1,TTYH2,LAMA2,SMAD1,CHIC1,MEF2C,MOV10,CD200,NRBP2,MT3,MYO7A,NEXMIF,NFIA,NFIX,NNAT,PAK3,PDGFRA,SEMA5B,PLEC,FXYD1,PLP1,RC3H2,EXOSC10,PPP2R5E,PRKACB,ELOVL2,PTPRE,PYGM,TMEM206,MEG3,SOX8,S100B,PRCD,SFPQ,SUPT20H,SH3GL2,ARX,BCAN,SLC1A6,EFHD1,SMARCA4,SNRPN,SON,ZCCHC24,SPP1,SULF2,ACSBG1,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,USP22,OBSL1,PUM2,HHIP,THRA,TMPO,TNS1,RBFOX2,NR2C2,TST,SGK3,UBTF,UCHL1,FLRT1,USP1,SF1,ZBTB16,ZFAND5,STOX2,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.05E-04 5.34E-01 5.60E-04 5.11E-03 101 432 "ARID1A,FAM135A,PKP4,APC,CDC14B,ARHGAP5,NUMB,BBS2,SEC11C,PTBP2,CDK11B,LRBA,ARHGEF2,SRSF11,COG1,NIPBL,PCYT1B,SLC4A7,IGDCC3,CLIP3,SNCAIP,FGFR1OP2,TOX,C8orf34,GSDME,DDX46,FAM107B,DYRK1A,DNM1L,ABCC9,EDIL3,KLHL5,MTSS1L,CEP85L,ETV1,NSRP1,WAC,TMEM132C,AFF2,SYT3,SMC2,STAU2,TMEM151A,GAP43,HIGD1B,ZNF276,GOLGB1,CIT,GUCY1A2,HLF,IGF1,KCNJ5,LIMS1,MAN2A2,SAMD5,RSPO2,NASP,NFE2L2,NPY,CLEC9A,NRGN,ODF2,PDE4D,PRIMPOL,PRRX1,DIRAS2,CNTLN,RAP1GAP,NWD1,ARID4A,ZYG11B,REV3L,ZFHX4,PLPPR3,CLIP1,DGLUCY,PREX2,DHX30,SEPHS1,TET1,SMARCC2,CDK5RAP2,SPATA7,BDP1,SOX11,ARHGAP26,RBM26,TCEA1,SATB2,SYNE1,PHF24,SIRT1,AMACR,TRO,STXBP4,TRPS1,ZKSCAN5,ZNF711,WNK1,HNRNPA3,CERS6" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_100 dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.06E-04 5.38E-01 5.64E-04 5.14E-03 29 88 "NR0B1,AMH,LGR5,PPP4R4,CADPS,CACNA2D2,CLU,SCRN1,DTNA,MRO,PLXNC1,EPS8,ERBB4,PTK2B,FGF13,GATM,PPARGC1A,GPR37,KCNH1,KLHL23,NELL1,PAK3,SERPINE2,RASGEF1B,TMEM206,MRAS,SMOC1,ADAMTS9,WNK3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_500 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.08E-04 5.50E-01 5.76E-04 5.25E-03 16 37 "ADAM23,NRP2,CACNA2D1,RAB3C,DNAJC6,MFAP3L,CPEB2,PDLIM5,DNER,IL6ST,KCNMA1,ZHX3,SYN2,SYNPO2,FAM13C,MSRB3" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_100 DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.10E-04 5.62E-01 5.88E-04 5.36E-03 28 84 "PNMA8B,ARHGAP20,BACH1,RUNX1T1,CHM,SLIT2,PLAA,RBM39,ZEB2,ZC3H11A,EDNRA,EIF4G1,EPB41L2,LPAR4,WIF1,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,TMLHE,MEG3,ARX,KLHL4,CBX5,SSBP2,FLRT2,ADAMTS9" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.10E-04 5.63E-01 5.88E-04 5.36E-03 47 168 "FMNL2,NR0B1,KCNT1,PPP4R4,NUMB,ATP2B3,CALB1,CDH10,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,RASGRP1,TMEM35A,EMX2,NRN1,GABRA4,GABRB1,PCDH11X,PACSIN2,KLHL23,KITLG,AFF1,MYO9A,NFIA,NUCB2,SERPINI1,PIK3C2A,ZFHX4,LGR4,HUNK,TNFRSF19,SLC4A3,SNCA,UHRF1BP1L,LRRC4,ST5,ADGRL3,DNAH7,ACTR6,FNDC5,PCDH20,ZNF23,DPF3" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_1000_k5 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.11E-04 5.66E-01 5.91E-04 5.39E-03 35 114 "SLC12A5,SFMBT2,ADAM23,MPDZ,COL9A1,CRMP1,NRSN1,PHF19,TMCC2,GRIN3A,SPEG,DPYSL4,NSG2,DACH2,KCNMB4,GP1BB,STMN2,LINGO1,INSM1,KCNK2,MEIS1,TAGLN3,NTRK2,PCDH8,PRRX1,DIRAS2,PTX3,DRAXIN,SLC30A10,SLC9A5,C11orf87,THSD1,TAL1,ANO4,CUX2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Top 40 GSE76381_ESMoleculeCountsPMLog2 1.12E-04 5.71E-01 5.95E-04 5.42E-03 50 182 "C1QTNF3,SPARCL1,CCDC146,CALB1,CBLN1,CDH2,CDO1,CLU,COL4A5,CNTNAP2,ABCA8,TMEM132C,ZIC4,ZMYND10,C1orf61,IQCG,TPPP3,GAP43,DNER,IGFBPL1,CFAP126,OLFM3,LIFR,LRP1B,RSPO2,NFIA,NTRK2,CNTN3,PAX6,PDE1A,PDE4D,PFKP,PLTP,FAT4,ZMAT4,RFX4,ZFHX4,LGR4,WLS,GALNT10,KIF27,TCF12,TEX15,TPM1,ZIC1,ZIC3,PMEPA1,DNALI1,FAM13C,NHSL1" Coexpression Atlas GSM854290_500 "Myeloid Cells, DC.8-4-11b-.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-1" "Immgen.org, GSE15907" 1.12E-04 5.72E-01 5.96E-04 5.43E-03 90 377 "CPNE2,FMNL2,DSCAML1,ADCY6,TMCC3,SEMA7A,FGD2,APP,SHTN1,CASK,ZBTB10,N4BP2L1,ADAM23,NRP2,CDH2,UBE2L6,ARHGAP22,CLU,STOML1,LY86,ANKRD35,SLC4A8,CSF1,ATRNL1,CST3,SDC3,CYBB,RABGAP1L,DSCAM,EFNA2,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,EXTL1,ZMYND15,NEK6,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,GYG1,HSF2,IRF8,DOCK7,SCIN,INSM1,TUBB2B,JAK2,KIT,LIFR,VWA5A,ASPRV1,ADAM11,MRPL42,NPR2,CLEC9A,NUCB2,PFKFB3,CDK14,SSH1,CCSER2,PLCL1,SLC22A23,ROGDI,ZDHHC14,RGS12,LRRK2,SEMA6D,SCN4B,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,ARHGEF9,TMEM150C,ARC,TCF7,PHF24,SLC44A1,SYNPO2,TUBB2A,SPIRE1,WNK1,TUBA1A,SIGLEC10,PLD4" Coexpression Atlas GSM605878_500 "Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2" "Immgen.org, GSE15907" 1.19E-04 6.06E-01 6.31E-04 5.75E-03 97 413 "RNF150,MTUS1,ALCAM,FGD2,APOC2,APP,SHTN1,CASK,ATP1A3,ADAM15,ST3GAL5,C1QC,DDR1,SCARB1,UBE2L6,ZFYVE9,LY86,ZNF385A,CDC42BPB,GDA,CSF1R,CSF2RA,CSF3R,GALNT9,CST3,SDC3,CTNND1,CX3CR1,CYBB,DOCK4,MYADM,KIAA0513,DGKG,DAPK1,SIRPA,ARRDC4,EBI3,RASA4,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,FGFR1,FGR,TPPP3,GCNT2,ADAP1,SLC2A6,PADI2,HP,IFI16,LRRC25,DOCK7,IL6R,ITGAM,L1CAM,LIFR,LDLRAD3,RTL5,NCF2,CLEC9A,PFKFB4,CDK14,PLTP,PILRA,PTAFR,PTPRO,PID1,C1orf54,PRR5L,ACER3,LRRK2,RTN1,SH3BP2,SLC8A1,SLC11A1,SLC12A2,ELMO2,RAP1GAP2,SULF2,FGD4,KIAA0930,TF,TIAM1,TNFRSF1B,TPD52,TRIO,LAT2,AMZ1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 1.20E-04 6.14E-01 6.38E-04 5.82E-03 73 293 "ACTN2,SLC24A4,TBC1D14,KIAA1324,SORCS2,SMIM17,GAS7,APOC2,LGR5,ATP1A3,BARD1,NRP2,IL33,CAMK2A,CAMK2B,REPS2,KCNAB3,CLU,SLC24A2,CREM,CRYBB1,MICAL2,PLCH2,DLG2,SNX29,RASGRP2,SEZ6,NCALD,CDKL3,SEMA4D,DLL3,ABLIM2,FYB1,ARPP21,LYVE1,NTNG2,ADAP1,GRIA1,TMEM25,SCIN,ZNF385B,ITGAV,KCNA6,GPR155,MITF,MOBP,BCO1,MYH3,ETFRF1,ENPP2,NXPH1,PRKAR1B,MASP1,GDPD2,STRC,VEPH1,ZMAT4,DUSP15,KCNIP3,SH3GL2,CCDC92,SLC1A2,SLCO1A2,INAVA,C11orf87,SAMSN1,ACSBG1,TMOD1,LAMP5,CADM2,PCDH15,DNAH10,PRRT4" Coexpression Atlas GSM605834_500 "Myeloid Cells, DC.8-4-11b-.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.21E-04 6.15E-01 6.38E-04 5.82E-03 95 403 "CPNE2,ACTN1,FMNL2,ADCY6,TMCC3,ADORA2A,SEMA7A,APP,SHTN1,CASK,ARHGAP5,ZBTB10,ATP2B1,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,ST3GAL5,CD86,CD81,LARGE1,UBE2L6,ARHGAP22,CLU,LY86,SLC4A8,CDC42BPB,OSBPL3,ATRNL1,CST3,SDC3,CYBB,GUCD1,PLPPR4,RABGAP1L,ARRDC4,PLXNC1,ENO2,EXTL1,ZMYND15,TMEM107,NEK6,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,GYG1,HMGCR,HSF2,IRF8,DOCK7,SCIN,INSM1,TUBB2B,JAK2,KIT,KTN1,VWA5A,NCOA7,ASPRV1,CD200,MYO9A,CLEC9A,PFKFB3,CDK14,SSH1,CCSER2,PLCL1,SLC22A23,EML5,ROGDI,ZDHHC14,LRRK2,RTN1,SEMA6D,ARHGEF40,CCDC88A,SAMSN1,SULF2,TMEM150C,ARC,ATP11A,TCF7,SIRT1,THBS4,SLC44A1,DDHD1,TNFRSF1B,TRPM2,CLIP2,ZBTB38,SPIRE1,ITM2C,PLD4" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.22E-04 6.20E-01 6.43E-04 5.86E-03 74 298 "EMILIN3,ACTN2,ADCY2,KIAA1324,SRPX,ARHGAP20,CDK10,ADGRB2,NRP2,ZNF599,C1QC,CACNA1G,LDLRAD4,CA12,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,CLU,ABI3BP,ANKRD44,CSF1R,CCDC3,DLG2,RASA4,ELN,EPB41L1,LRRC17,EPS8,FCGRT,TRIM16,FYB1,ARPP21,TMEM8B,ZNF276,GSN,WIF1,SYNPO,IL11RA,CREG2,VWA5A,SRSF12,MOBP,TCEAL5,NFIA,NFIX,CNTN3,PLCL1,NXPH1,PRKAR1B,GDPD2,ACSS3,ZCWPW1,ZMAT4,ZFHX4,MYH14,DGLUCY,ATXN1,SH3GL3,ASAP3,DOCK10,SLC1A2,SLC6A9,SLC8A1,ZFR2,UNC5D,ADGRL3,PHF24,FAM189A1,TSPAN11,PMEPA1,CADM2,PCDH15" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_200_k4 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.23E-04 6.25E-01 6.48E-04 5.90E-03 24 68 "ABAT,ARHGAP20,VAT1L,LGI1,CHGB,CNTN1,EBF1,MRVI1,DACH2,MEGF10,DNER,FREM1,GRIA1,PTPRT,NEGR1,MN1,PTX3,ZFHX4,SLC14A1,CLSTN2,NEK4,ANO4,THBS4,NETO1" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k1 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.23E-04 6.27E-01 6.49E-04 5.92E-03 52 192 "ADCY5,SRPX,ANK1,PI16,ATP2A2,MYOM1,NRP2,CAMK2D,DMPK,CPEB2,DTNA,ABCC9,MRVI1,FHL1,FLNC,SORBS1,ILDR2,IGSF5,PRUNE2,BVES,IL6ST,ALDH1L2,NPTX2,PFKP,PRKAB2,PRKCB,PTHLH,RYR3,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,LIMS2,RIMS1,FNBP1,DBNDD2,NACAD,POPDC3,ENHO,TNNT1,TNS1,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,ZBTB16,RGS7BP,FAM13C,ACTR3B,MSRB3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k5_1000 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.23E-04 6.30E-01 6.51E-04 5.93E-03 49 178 "EMILIN3,USP31,TAOK1,ALCAM,APAF1,PHYHD1,SFMBT2,TMEM263,BARD1,BCHE,CACNA2D1,VSTM2A,SRSF11,SOCS6,SLIT2,CRHBP,VCAN,MYEF2,ETV1,DLC1,PDLIM5,ARFIP1,PCDH17,GHR,PCDH11X,RASSF8,ZDHHC15,RBPJ,CHIC1,MEF2C,MKLN1,MMP16,SAMD5,MYO6,ASRGL1,ST8SIA1,SOX5,ZHX3,PEG10,C11orf87,AGTPBP1,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1,UBE3A,WRN,NETO1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_100_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.25E-04 6.35E-01 6.56E-04 5.98E-03 17 41 "PCDH10,TOX,SPOCK3,EPHA5,TMEM132C,FOXF2,MEGF10,DNER,GRIA2,IFI16,MYH3,TRHDE,PRRX1,ZFHX4,CSRNP3,UNC5D,TBX15" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_1000_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.25E-04 6.37E-01 6.58E-04 6.00E-03 44 155 "ACTN2,APOC2,SPTBN4,ZFYVE28,ARRB2,PDE8B,DACT3,ATP1A3,BARD1,ZNF599,GPC2,IL33,KCNAB3,CCPG1,VAX2,CRYBB1,PLCH2,PTK2B,HPCAL4,ZMYND15,ABLIM2,ARPP21,NTNG2,GRK4,HPSE2,ICA1,KNDC1,SCIN,LIX1,ZNF385B,GPR155,CPNE9,BCO1,TCEAL5,PDE4D,STRC,DUSP15,MYH14,SLC1A2,SAMSN1,LEFTY2,TMOD1,PMEPA1,DNAH10" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.25E-04 6.39E-01 6.59E-04 6.00E-03 80 328 "ADCY2,ARHGAP20,LRRC4C,RASL11B,TMEM108,MYRF,KALRN,CBLN1,CDH10,SLIT2,CNTFR,AKAP5,CLIP3,TENM4,ATRNL1,VCAN,BOC,ZEB2,TIAM2,SV2A,DNM1,TSPAN5,EDNRA,C8orf37,F3,FABP7,TUBB4A,AMOTL2,MEX3B,FLNC,NSG1,TRAF3IP2,DENND2A,FREM1,CSDC2,GHR,GLI2,GUCY1A2,GUCY1A1,TCEAL6,NKD1,MAP2,MATN2,MEIS1,MEIS2,TCEAL5,NCAM1,ZC3H12B,NEFM,NNAT,NME4,PDGFRA,PIK3R1,PCDH18,PRRX1,SYTL2,LAMA1,PTN,RADX,RIC8B,ROBO2,MEG3,KCNIP1,CLIP1,PKNOX2,PALLD,ZC4H2,SULF2,KLHL7,PSD3,ASXL3,TPM1,TRPS1,SSBP2,TMEFF2,PLEKHH2,VSNL1,ZFP37,ZNF184,ST8SIA2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_200 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.26E-04 6.43E-01 6.63E-04 6.04E-03 13 27 "CRMP1,CLIP3,TUBB4A,NSG1,GNG3,CELF3,ACOT7,TAGLN3,SLC10A4,GDAP1L1,PRPH,SST,UCHL1" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k4 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.28E-04 6.51E-01 6.70E-04 6.10E-03 38 128 "LCORL,ARHGAP5,CHM,KMT2C,NMT2,RBM39,TENM4,DZIP3,FGFR1OP2,CALCRL,EMX2,SCML2,KIAA1109,GABRA4,ILDR2,TUBGCP4,NR3C1,KIF3A,MIER3,KCND2,CNOT4,PDPK1,OLA1,PLEC,TMLHE,LRRTM4,FNIP1,SLC12A2,SCMH1,CPEB4,SNCA,SYNE2,ANKRD12,AHCYL2,TSC1,ZNF711,ADAMTS9,NAV2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.32E-04 6.74E-01 6.93E-04 6.32E-03 29 89 "USP31,APC,MIER1,FOXN3,VCAN,ZEB2,DNM1,GFRA2,GRIA2,RASSF8,BACH2,KIF5C,MEIS2,NFIA,PRRX1,KANSL1,PTPRG,PTPRO,ROBO2,ZHX3,CLASP2,EPB41L3,ADGRL3,PCDHB7,ZFP91,ERCC6L2,RBFOX2,TRPS1,NUP214" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_2500_K3 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.33E-04 6.77E-01 6.95E-04 6.34E-03 127 569 "ABAT,EMILIN3,HECW2,RTL9,SEMA6A,ANK1,ANK3,KCNAB2,CACHD1,CDK10,IGDCC4,RASL11B,BMPR1B,CACNA1G,CACNA2D1,RUNX1T1,CRLF1,DIS3L,NIPBL,COL9A3,ABI3BP,IGDCC3,ENTPD4,ANKRD44,SNCAIP,ATRNL1,BOC,ARHGAP24,RHOBTB1,GRIN3A,DNM1,USP3,ABCC9,MBNL2,EPB41,LRRC17,DENND4A,HSPA12B,FDFT1,TESK2,FECH,SCARA3,FOXF2,TRIM16,TMEM151A,TVP23A,CPLX2,NEU3,GFRA2,FREM1,ZNF276,RAB30,GRIK4,GSN,WIF1,SYNPO,AGBL5,IL11RA,INPP1,ITPKB,JAK2,LAMA2,LAMP2,VWA5A,SMAD9,MAN2A2,SRSF12,MSR1,RSPO2,FXYD7,NFIX,CLEC9A,NRGN,ZNF827,PDE3A,PDE4D,PENK,PFKFB2,CDK14,FTO,PRRX1,EPB41L4B,CCDC144B,CRLS1,CNTLN,IQSEC3,FAT4,BEND5,RBBP8,ZFHX4,MRAP2,BAALC,ATXN1,SH3GL3,DOCK10,NTNG1,CNKSR2,DZIP1,SLC8A1,PDZRN3,DOP1A,CDK19,EPB41L3,ARHGEF9,PLCB1,TACR1,ANKRD12,KAZN,TBX15,TCF4,SATB2,SYNE1,HIF3A,ANKRD24,PIK3R5,SYNPO2,TRO,TRPC3,TRPS1,RFTN2,TSPAN11,WIPF1,ZNF32,NAV3,ADAMTS10,KLHDC1,FRMD6" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_500 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.34E-04 6.83E-01 7.01E-04 6.39E-03 15 34 "ARHGAP20,APOC1,REPS2,BOC,SRGAP3,AFF2,NSG1,TCEAL6,KCND2,MAP2,NFIA,PDE1A,PCDH18,MEG3,VSNL1" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.35E-04 6.87E-01 7.04E-04 6.42E-03 35 115 "SEMA7A,APOC1,SHTN1,CDC14B,TMEFF1,RGS11,DST,ST3GAL5,RGN,CDH2,ADGRG1,CLU,GPRASP1,MRO,PLXNC1,CERCAM,FAM198B,AFF2,CAMKK2,GATM,GPR37,RABL2A,SYTL4,MOV10,ETFRF1,SEMA5B,TMEM206,RPS6KA2,MRAS,TNIK,TSPYL2,SZT2,TST,ADAMTS9,WNK3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_100 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.39E-04 7.08E-01 7.25E-04 6.60E-03 28 85 "PCDH10,INSYN2B,DST,TOX,SPOCK3,EPHA5,TMEM132C,FOXF2,SGIP1,DACH2,MEGF10,GABRB1,DNER,GRIA2,WIF1,IFI16,RSPO2,MYH3,TRHDE,PRRX1,ZFHX4,CSRNP3,SCN3A,SOX2,TAC1,UNC5D,TBX15,SYNPO2" Coexpression Atlas gudmap_developingKidney_e15.5_1000_k1 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.39E-04 7.11E-01 7.27E-04 6.63E-03 41 142 "BEND6,TNRC6C,CACNA2D1,CFL2,NMT2,ZEB2,DNM2,GOLT1B,SYNCRIP,SMC2,PDLIM5,DKK3,RAPGEF6,ZHX1,LIMS1,CHIC1,MEIS1,MKLN1,CNTN3,ENPP2,PENK,PFKP,RC3H2,PRRX1,RASGRF1,ZFP2,SORCS3,FAM126B,ZHX3,KIF1B,EPB41L3,NEK4,ARHGEF9,VPS13A,WASHC4,ZFP91,ERCC6L2,RGMB,GOPC,MSRB3,SOCS4" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_500 dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.43E-04 7.31E-01 7.47E-04 6.81E-03 97 415 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,NRP2,ARHGEF7,C1QC,LDB2,FMNL3,CD38,MS4A7,JAM2,ABCG2,TMEM184B,ZNF521,HAPLN1,CSF1R,CX3CR1,CYBB,DOCK4,RASSF2,PITPNC1,ELMO1,ECM2,EBF1,EDIL3,EDNRB,LPAR6,PLEKHA1,CALCRL,PLEKHO1,RASGRP2,DENND4A,CORO2B,DLC1,KIAA1109,FLT1,PDLIM5,FYB1,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,RAPGEF4,MAP4K5,ICA1,IGF1,ITPKB,KIT,LMO2,TM6SF1,MEF2C,KITLG,CLEC9A,OPHN1,PDE2A,PDE4B,GNG2,PLCL1,SPATA6,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,MAGI3,PREX2,BTBD3,CPEB4,LIMCH1,UNC5B,THSD1,PLCB1,KLHL4,TCF4,TEK,TF,TIE1,HEY1,TJP1,TRPC3,DCBLD1,RFTN2,WIPF1,ZNF711,NAV3,FAM13C,RNF146" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_500_k4 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.45E-04 7.40E-01 7.53E-04 6.86E-03 27 81 "JAZF1,CACNB2,ABI3BP,TENM4,GSDME,G3BP2,PLXNC1,ELAVL2,ILDR2,GATM,AIFM3,MAP7D2,KIF3A,SHISA6,KIT,RSPO2,NEXMIF,ABCB1,PLP1,MAPK10,GDPD1,CPEB3,MYT1L,SYNE2,ANKRD12,RASD2,NDRG4" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_HindBrain_100 e8.5_NeuroEpith_HindBrain_top-relative-expression-ranked_100 FaceBase_ST1 1.45E-04 7.40E-01 7.53E-04 6.86E-03 27 81 "FZD9,VAT1L,FGF17,CA4,CBLN1,CLDN10,CIART,SOCS6,CNTFR,SCRN1,IP6K1,EN2,PIPOX,REEP2,PHYHIPL,GBX2,UBE2QL1,ELOVL5,ICA1,NKD1,AQP11,ELOVL2,WLS,SOX2,TRH,FAM181B,ACTR3B" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.45E-04 7.40E-01 7.53E-04 6.86E-03 27 81 "KLHL13,NR0B1,PPP4R4,CACNB2,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DCT,DRP2,EMX2,MTSS1L,GABRA4,PCDH11X,KLHL23,KITLG,NFIA,SERPINI1,LGR4,RASA3,SLC4A3,KDM3A,ADGRL3,ACTR6,TNNT1,FNDC5" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.46E-04 7.43E-01 7.56E-04 6.89E-03 12 24 "CADPS,CACNA2D1,CNTN1,ZEB2,EPB41L2,MRVI1,DACH2,NEGR1,CLDN11,PTX3,VWC2,SYNPO2" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 1.46E-04 7.45E-01 7.57E-04 6.90E-03 31 98 "ERMN,MAP7,INA,LHX2,FAM169A,RRAGB,TUBB4A,FGF11,GABRB3,SALL3,STARD10,GLDC,TOX3,CECR2,PSIP1,NRCAM,IGSF11,PRTG,MAGEL2,PRODH,SALL1,NTNG1,LARP4,AJAP1,ROBO3,WWC1,WASHC4,TNNT1,SLAIN1,ZIC2,ZBTB16" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_200 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.46E-04 7.45E-01 7.57E-04 6.90E-03 31 98 "AMPH,CDH2,CNTFR,CRYM,SNCAIP,VCAN,GSDME,SNAP91,ELAVL4,KCNMB2,ETV1,EYA1,FGFR1,IGSF5,GFRA1,TDRKH,CECR2,FAM107A,HAS2,NEGR1,NCAM1,NELL1,CNTN3,FAT3,MDGA2,TMEM100,SALL1,SLC1A3,CUX2,CADM1,LAMP5" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO fibroblast_cfr-2X-p05 ECTO blastocyst_vs_ECTO fibroblast-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.50E-04 7.67E-01 7.78E-04 7.09E-03 36 120 "AXIN2,ADORA1,PCDH10,RASL11B,NRP2,BMP7,LGI1,NOG,SLIT2,COL11A2,NRG2,TENM4,LYPD1,EDNRA,EPHB1,TMEM132C,ITPKB,KCNA1,CLEC18A,SAMD5,PDE2A,PDE1B,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,RELN,RFX4,TNFRSF19,SLC30A10,SLIT1,SNCA,SPP1,TAC1,TMEFF2,DOCK8" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.51E-04 7.68E-01 7.78E-04 7.09E-03 26 77 "ACHE,APLP1,ARHGDIG,ASCL1,ATP1A3,CCK,CLTB,CNTFR,CNRIP1,SLC35F1,CACNG7,NELFCD,TMEM107,KCNMB4,GP1BB,B4GALNT4,ACOT7,LMO1,NPY,GNG2,NLGN3,FXYD1,POLR2F,ELOVL2,S100B,SOX10" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k3 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.53E-04 7.78E-01 7.86E-04 7.17E-03 40 138 "RNF157,SLC12A5,LDLRAD4,RUNX1T1,CDH2,CDO1,SLIT2,NCOR1,APPL1,PYGO1,HDAC9,CEP170,EDIL3,ETV1,SCML2,FOXF2,MEGF10,GABRA4,GABRB1,PCDH17,RAB40B,EML4,KLF12,IFI16,KCNK2,NAP1L2,PCDH8,PFKFB3,GRAMD1C,FAT4,RGS4,ZFHX4,ARMH4,SON,NPAS3,PLCB1,MTCL1,HIF3A,TRPS1,SOCS4" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k5_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.53E-04 7.78E-01 7.86E-04 7.17E-03 40 138 "TAOK1,LCORL,LGR5,RNF182,CHM,NMT2,RBM39,TENM4,DZIP3,DOCK4,FGFR1OP2,G3BP2,DTNB,ELAVL2,EMX2,FAM198B,SCML2,ATP8A1,GABRA4,TUBGCP4,KIF3A,TOX2,KCND2,KITLG,CNOT4,PDPK1,JAKMIP1,ANKHD1,TMLHE,FNIP1,SYBU,SLC12A2,SCMH1,CPEB4,LARP4,SYNE2,ACTR6,TBC1D15,ZNF23,ADAMTS9" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000_k4 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.55E-04 7.90E-01 7.98E-04 7.27E-03 65 256 "ADD3,PCDH19,ARHGAP20,PTCH2,ATP2B1,ADGRB3,IL33,VSTM2A,RUNX1T1,LDB2,ZNF445,COL4A5,CSF1R,CX3CR1,ZEB2,ZC3H11A,CDON,EDNRA,SEMA3D,APH1A,ETV1,TMEM132C,FCGRT,SEMA6C,NBEA,SMC2,TNRC6A,PARD3B,GRIK1,GRM7,WIF1,RASSF8,HAS2,KLF12,KCND3,MATN2,MEIS1,MEIS2,MMP16,SAMD5,MYBPC1,NFIA,PCDH9,PCSK5,NALCN,PIK3R1,PLCL1,PRRX1,FAT3,PTN,C1orf54,RNASEL,MEG3,TET1,ARFGAP1,PRRC2C,TCF7L2,WASHC4,PCDHB9,HIF3A,TRPS1,SSBP2,FLRT2,VLDLR,ZNF142" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.56E-04 7.93E-01 8.00E-04 7.29E-03 30 94 "AXIN2,LGR5,CACNA1D,MAGI2,SRGAP3,NSG1,GABRB1,TCEAL6,IGF1,PLD5,KCND2,MTR,LAYN,NEXMIF,NPR2,PDE1A,ENPP2,CDK14,GDPD2,FAT4,RNASEL,SEMA6D,TNFRSF19,SCMH1,NPAS3,ADAMTS17,TCF12,DAAM2,DCBLD1,LYPD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k1 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.56E-04 7.93E-01 8.00E-04 7.29E-03 20 53 "EMILIN3,DNM1,IQGAP2,GFRA1,GRIA2,KLF12,NFIA,PDE3A,PRRX1,FAT3,KANSL1,REV3L,SMOC1,EPB41L3,CAMSAP2,HHIP,ERCC6L2,RBFOX2,RGMB,NUP214" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k4_1000 dev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.60E-04 8.15E-01 8.21E-04 7.48E-03 116 514 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,SHROOM2,DOCK11,ADAM15,NRP2,ARHGEF7,C1QC,LDB2,FMNL3,CD38,ARHGEF2,MS4A7,JAM2,ABCG2,TMEM184B,ARHGEF6,CRMP1,HAPLN1,CSF1R,CX3CR1,CYBB,TOX,KIAA0513,RASSF2,GIT2,PITPNC1,ELMO1,FAM107B,ECM2,EBF1,EDIL3,SH3GLB1,LPAR6,CALCRL,PLEKHO1,DMTN,RASGRP2,STX2,DENND4A,CORO2B,FCGR1A,FLT1,UFM1,PDLIM5,TRIM16,FYB1,GAP43,PCDH17,GGTA1P,LYVE1,HPGDS,GLUL,LILRB4,LPAR4,RAPGEF4,MAP4K5,NCKAP1L,ELOVL5,ICA1,IFI16,ITPKB,LIFR,LMO2,TM6SF1,MEF2C,MSR1,MYO6,CLEC9A,OPHN1,PDE2A,PDE4B,PDE4D,SCHIP1,SPATA6,DRAM2,MAPK3,PROX1,SLC22A23,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,PRR5L,SGK1,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,SAMSN1,THSD1,KLHL4,TCF4,TEK,TF,C18orf54,TIE1,HEY1,TJP1,TLR4,TRPC3,RFTN2,WIPF1,ZNF711,NAV3,FAM13C,ZDHHC20,RNF146" Coexpression Atlas GSM538249_500 "Myeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3" "Immgen.org, GSE15907" 1.64E-04 8.36E-01 8.41E-04 7.66E-03 92 391 "PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,CADM3,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,CTNND2,USP6NL,CYBB,DOCK4,MYADM,SIRPA,CDON,DSCAM,ARRDC4,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FGR,GATM,GCNT2,MALT1,RAB30,GPM6B,ADAP1,ZNF496,GSN,FRMD5,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KCNJ16,KIT,ASPRV1,ADAM11,STK32C,ADAM22,LINC00672,MYO5A,CLEC9A,PFKFB3,CDK14,ABCB1,PLTP,RASGEF1B,PTAFR,PTK2,TMEM231,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SCN3A,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,MYCBP2,RGL1,SULF2,ADGRL3,CYB561A3,SLC44A1,DDHD1,TNS1,NPL,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_200_k4 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.65E-04 8.40E-01 8.44E-04 7.69E-03 29 90 "CALB1,CRLF1,TMEM59L,HAPLN1,CNTNAP2,CTNND2,DUSP9,EMX2,SPSB4,FGF12,RASL10A,GFRA1,MAP7D2,GRIK1,MFSD2A,PADI2,FRMD5,VWA2,EML5,RASGRF2,RET,SOX8,SCN4B,LRRC4,NUDT10,UNC5D,TCF7,RPRM,VSNL1" Coexpression Atlas facebase_RNAseq_e10.5_OlfacPit_2500_K2 facebase_RNAseq_e10.5_OlfacPit_2500_K2 Gudmap RNAseq 1.65E-04 8.40E-01 8.44E-04 7.69E-03 29 90 "ACHE,ADD2,NOL4,NRP2,NRXN3,IGDCC3,MICAL2,ELAVL4,ADGRV1,TPPP3,CCDC184,GRIK2,CELF3,TOX2,FRMD3,MAP6,MAPT,SHC3,NCF2,SERPINI1,ZMAT4,RGS4,SNAP25,INKA2,GALNT17,TRPC1,CA14,TMEFF2,AP3B2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k2_100 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.67E-04 8.51E-01 8.52E-04 7.77E-03 9 15 "CLIP3,ATL1,GNG3,CELF3,PCBP3,SLC10A4,PRPH,SST,TMEFF2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_100 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.67E-04 8.51E-01 8.52E-04 7.77E-03 9 15 "CNTFR,CLIP3,GFRA2,GNG3,TAGLN3,SLC10A4,PRPH,SST,UCHL1" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.69E-04 8.63E-01 8.63E-04 7.87E-03 63 247 "ACLY,ABHD6,GPRASP2,CDK10,PDXK,ADAM23,BMPR1B,SCAPER,CACNA2D1,LRBA,CDO1,CRLF1,DIS3L,CREB5,CLIP3,PHF14,TOX,DDX46,CCDC3,ELN,EPB41,LRRC17,CORO2B,FCGRT,FDFT1,HPCAL4,ZNF276,GLRB,GSN,SYNPO,KNDC1,LRRCC1,LIX1,IL11RA,TM6SF1,MEIS2,SRSF12,MXI1,NFIX,CLEC9A,ODF2,PDE3B,GPSM2,CRLS1,DIRAS2,CNTLN,IQSEC3,ENOX1,RBBP8,ATXN1,NTNG1,DOP1A,TRERF1,BDP1,ANKRD28,PHF24,STXBP4,TRPS1,USP1,LYPD6,PMEPA1,CERS6,ST8SIA2" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K3 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.71E-04 8.71E-01 8.71E-04 7.94E-03 76 311 "NDRG2,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,CACNA1B,MAP7,CBARP,MYL6B,LETMD1,MYADM,SPOCK2,C8orf34,RABGAP1L,SEMA3D,EFNA3,EGFR,RGS17,RPS6KC1,MED12L,FGF11,FGF12,SEMA6C,STAMBP,TPPP3,TVP23A,GAD2,STARD10,PCDH17,GLRB,PCDH11X,PARD3B,NR3C1,FAM107A,FRMD3,LRRC75A,KCNK1,MBP,IL17D,MEIS1,MOV10,CCDC80,SAMD14,HS6ST3,PIRT,GPR173,SERPINE2,SMOX,FXYD1,NECAB2,RAB3A,RNH1,LGR4,ATXN7,HES6,FERMT1,CLSTN1,PALLD,DOK5,UNC5B,INKA2,ADAMTS17,MCF2L,PCDHGA2,TEX15,SLC44A1,ENHO,TNNT1,TPD52,TST,TOM1L2,PORCN,NDRG4,SH3GLB2,TMEM163" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.74E-04 8.87E-01 8.86E-04 8.08E-03 28 86 "ADCY2,CADPS,CALB1,NRXN3,CNTN1,CRYM,EPB41L2,DACH2,DKK3,GABRA1,GALC,NEGR1,KCND3,NCAM1,CLDN11,PCDH8,PENK,KANSL1,PTPRO,PTX3,REV3L,CAMSAP2,ANO4,VWC2,ERCC6L2,SYNPO2,TMEFF2,NAV3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_200 dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.75E-04 8.90E-01 8.88E-04 8.10E-03 47 171 "FMNL2,SLITRK1,NR0B1,KCNT1,PPP4R4,ATP2B3,CALB1,DCLK1,CHRM4,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,EMX2,NRN1,AFF2,GABRA4,GABRB1,PCDH11X,KLHL23,MATN2,KITLG,AFF1,MTR,MYO9A,PDE1A,SERPINI1,PCDH18,TMEM206,LGR4,TNFRSF19,RASA3,SLC4A3,SNCA,KDM3A,UHRF1BP1L,SMOC1,ADGRL3,TEX15,DNAH7,ZFPM2,ACTR6,FNDC5,PCDH20,WNK3,DPF3" Coexpression Atlas GSM538245_500 "Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.76E-04 8.96E-01 8.93E-04 8.14E-03 95 407 "FMNL2,RNF150,PTCHD1,ALCAM,SEMA7A,FGD2,APP,SHTN1,CASK,ATP1A3,CADM3,ADAM23,NRP2,DST,HAP1,CD86,CHN2,B4GALT6,CLU,LY86,SLC4A8,ZNF385A,GDA,CSF1R,CSF2RA,ATRNL1,SDC3,CTNND2,CX3CR1,CYBB,DOCK4,DAPK1,SIRPA,ZEB2,DSCAM,PLXNC1,RASA4,PLEKHO1,EPS8,IGSF6,SIRPB1,OLFM1,FGR,ZMYND15,GATM,GFRA2,RAB30,ADAP1,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KIT,ADAM11,STK32C,ADAM22,MYO5A,NCF2,CLEC9A,PFKFB3,CDK14,PLTP,RASGEF1B,PTAFR,PTK2,PTPRO,MARCH1,PID1,ROGDI,PRR5L,LRRK2,RTN1,SCN3A,ST8SIA1,SLC8A1,CCDC88A,TRERF1,ITPRID2,RGL1,SULF2,ADGRL3,TF,SLC44A1,TIAM1,DDHD1,TNS1,TRIO,TRPS1,LAT2,SPIRE1,SIGLEC10,PLD4,JMJD1C,NLRP3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200 dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.77E-04 9.03E-01 9.00E-04 8.20E-03 42 148 "NDRG2,ALCAM,ARHGAP20,RUNX1T1,CBLN1,VCAN,ZEB2,EDNRA,HEYL,EGFR,PLXNC1,LRRC17,NRN1,FABP7,DLC1,FLNC,GFRA2,FREM1,PPARGC1A,GLI2,PCDH11X,GRIA4,GUCY1A2,GUCY1A1,HPSE2,MAP2,NCAM1,PCDH9,PDGFRA,PCDH18,FAT3,PTCH1,PTN,TMEM255A,ROBO2,MEG3,PALLD,SULF2,ADGRL3,HHIP,VSNL1,STOX2" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_200 kidney_P2_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.81E-04 9.21E-01 9.16E-04 8.35E-03 40 139 "ALCAM,AMPH,IL33,CA12,CACNA2D1,CDH2,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,GSDME,SNAP91,ELAVL4,KCNMB2,ETV1,EYA1,ST3GAL6,FGFR1,IGSF5,GFRA1,TDRKH,CECR2,FAM107A,HAS2,NEGR1,NCAM1,NELL1,CNTN3,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1,SLC1A3,CUX2,TPM2,CADM1,LAMP5" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_200 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.82E-04 9.30E-01 9.25E-04 8.43E-03 45 162 "DOC2A,BMP7,CALB1,CRLF1,TMEM59L,HAPLN1,IPCEF1,CNTNAP2,CTH,CTNND2,DUSP9,TENM1,EMX2,SPSB4,FGF12,RASL10A,GALC,GFRA1,MAP7D2,GRIK1,MFSD2A,PADI2,FRMD5,IGFBP1,KCNJ16,KIF5C,L1CAM,AQP11,VWA2,LAMA1,EML5,RASGRF2,RET,PRR5L,SOX8,SCN4B,SCN8A,FHOD3,LRRC4,NUDT10,UNC5D,TCF7,RPRM,VSNL1,LRP8" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_500_k3 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.83E-04 9.32E-01 9.25E-04 8.43E-03 27 82 "ADCY2,LRCH2,APAF1,TNRC6C,CACNA2D1,CCDC3,MRVI1,SYNCRIP,DNER,FREM1,PCDH11X,RAB40B,CACFD1,NEGR1,MEF2C,MMP16,PENK,ZHX3,NEK4,RHBDL3,ANO4,ZFPM2,TLR4,ZFP91,PLSCR4,FAM13C,SOCS4" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29977_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.84E-04 9.36E-01 9.28E-04 8.46E-03 163 764 "SLC12A5,USP31,BEND6,HECW2,ADGRF5,FGD2,C6orf89,APBB2,DGKZ,SHROOM2,ARRB1,ARRB2,NRP2,ARHGEF7,C1QC,LDLRAD4,CA8,CANX,LDB2,FMNL3,CD86,SCARB1,CD38,MAP4K4,LY86,ZFP28,CNRIP1,RBM39,CRMP1,HAPLN1,ABCG1,CSF1R,LRRC3B,PPP1R16B,CX3CR1,CYBB,KIF26A,RASSF2,SIRPA,PITPNC1,ELMO1,FAM107B,CCDC3,KBTBD11,DNM2,GNE,ABCC9,SEZ6L2,EDNRB,HIPK3,SH3GLB1,EBI3,RASGRP2,EPHB1,IGSF6,RCSD1,TLR7,SIRPB1,F8,CORO2B,DLC1,FCGR1A,TOMM40L,FLT1,SMC2,TRIM16,FYB1,FAM184B,GALC,GAP43,PCDH17,GGTA1P,LYVE1,GPR12,RAPGEF4,NCKAP1L,HP,ICA1,IRF8,IGF1,KIT,STXBP5,LMO2,PIK3AP1,MAP4,TM6SF1,MEF2C,MEIS2,KITLG,CD200,MSR1,MYO7A,NCF2,NFE2L2,OPA1,P2RX7,PDE2A,PDE4B,GNG2,PFKP,SEMA5B,SCHIP1,KANSL1,RELN,SNRK,PTPRB,RIPOR1,TMEM255A,SH3TC2,RGS3,KCTD17,ATP8B4,PRR5L,MAPK12,SGK1,FAM102A,SHMT2,ST8SIA1,SLA,PREX2,SMTN,SLC9A5,SLC11A1,LIMCH1,MYCBP2,ARHGAP26,SAMSN1,THSD1,NEK4,RGL1,SLC37A2,TAL1,CAMSAP2,KLHL4,WSCD1,TNS2,ARHGAP9,SIK3,TEK,TF,TIE1,TLR4,ERCC6L2,TNFRSF1B,NPL,TRIO,TRPC3,DCBLD1,TTPA,VAV1,WIPF1,NPDC1,AMZ1,INTS3,GDPD5,ADAMTS9,PLD4,RGS7BP,FAM13C,DOCK8,NUP214,MSRB3,SPATA13" Coexpression Atlas GSM538198_500 "B cells, B.Fo.PC, IgD+ IgM+ CD19+ CD43- CD5- CD23+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.89E-04 9.62E-01 9.54E-04 8.69E-03 84 352 "ADD3,SNX30,ZNF608,TXNDC16,BCAR3,CARNS1,FGD2,DGKD,INSYN2B,ATP2B1,ATP6V0A1,BCL7A,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,CDC25B,LY86,CNN3,SLC4A7,CSNK1G3,ATRNL1,KIAA0040,RUBCN,CYBB,HDAC9,MYADM,RIPOR2,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,HVCN1,B4GALNT1,ACSS1,MALT1,RAB30,DCLK2,EML4,CECR2,RAPGEF4,TPPP,ADAMTS6,IRAK3,KLF12,BACH2,IL12A,MEF2C,CD200,MYO5A,PDE3B,PPP3CA,PPP3CC,RASGEF1B,PRKCB,SIDT1,PXK,MARCH1,RALGDS,BEND5,LRRK2,MAPK12,SELL,RASA3,ST6GAL1,LMBRD1,ARHGAP26,STAC2,SLC37A2,MGRN1,TCF4,CYB561A3,C9orf85,TRIO,LAT2,SIGLEC10,TMEM163,MPPE1,PLD4,PHTF2" Coexpression Atlas GSM399362_500 "alpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3" "Immgen.org, GSE15907" 1.89E-04 9.64E-01 9.54E-04 8.70E-03 74 302 "ACTN1,ADCY6,AXIN2,OSBPL8,ARHGAP20,PITPNM2,SFMBT2,ARNTL,FUBP1,ARHGEF1,CNN3,ARHGEF6,AKAP12,LRIG1,IPCEF1,SIPA1L1,TOX,DLG4,ABCC5,RASGRP1,KIAA1109,CAP2,TACC2,NSG2,FYN,CHL1,RAPGEF6,KCNMB4,DCLK2,RAPGEF4,BACH2,IL6ST,ITPKB,STMN1,HECTD2,ZNF827,PDE4D,TMIE,SPATA6,PACSIN1,SH3KBP1,PRKCZ,SYTL2,BEND5,REV3L,RGS3,PBRM1,RAVER2,ZNF354C,SATB1,IL17RB,GALNT10,FAM102A,MAGI3,ST6GAL1,ST8SIA1,DZIP1,TET1,TNIK,SP4,ERC1,VAMP1,KLHL4,TCF7,TGFBR3,TIAM1,BHLHB9,KAT6B,TRIO,SSBP2,TTC3,MAP3K12,NAV2,SENP7" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K0 facebase_RNAseq_e10.5_Emin_MedNas_2500_K0 Gudmap RNAseq 1.90E-04 9.69E-01 9.59E-04 8.74E-03 33 108 "TTYH1,NOL4,CA12,CAMK2A,JAM2,IQCK,IGDCC3,FEZ1,ELAVL2,ELAVL4,ERBB4,ADGRV1,FABP7,AFF2,CECR2,GRIK2,RNF165,CELF3,TOX2,KIF5C,MAP2,MAP6,NNAT,HSPA4L,SNAP25,ANKFN1,SOX2,INKA2,WSCD1,CA14,ZBTB16,DPYSL5,AP3B2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Overall_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Overall_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.92E-04 9.78E-01 9.66E-04 8.81E-03 49 181 "SPARCL1,CDC42BPA,MAP4K3,CD81,CDH2,CHN1,NRXN1,ARHGEF6,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,SGIP1,HIGD1B,GNAS,FERMT2,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,CLSTN2,CADM1,CLDND1,TUBA1A,ADAMTSL3" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k5 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.92E-04 9.81E-01 9.68E-04 8.83E-03 18 46 "ADCY2,CADPS,NRXN3,CNTN1,EPB41L2,DACH2,DKK3,NEGR1,KCND3,NCAM1,CLDN11,PENK,PTX3,ANO4,VWC2,SYNPO2,TMEFF2,NAV3" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_1000 kidney_P2_CapMes_Crym_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.93E-04 9.83E-01 9.70E-04 8.84E-03 139 637 "ABR,NDRG2,RNF157,MTUS1,TXNDC16,ALCAM,CEP126,AMPH,VAT1L,ADAM23,BARD1,BCHE,BCL7A,BMP7,IL33,CA12,CACNA2D1,CACNB4,CDH2,CHRNA4,CNTFR,BTF3L4,CLIP3,CRYM,SNCAIP,SIPA1L1,VCAN,CTH,ECE2,BOC,PHF19,TM9SF4,SPOCK2,GSDME,SNAP91,SV2B,DLG4,ARRDC4,DTNA,EDNRA,HEYL,ELAVL4,C8orf37,KCNMB2,ETV1,EXTL2,EYA1,ST3GAL6,FCGRT,SLC9B2,FGF1,FGFR1,MAD2L2,SCARA3,CAP2,WDR83,TMEM107,STAU2,MTHFD2,IGSF5,FAXC,GFRA1,GFRA2,FREM1,GLDC,GLRB,TDRKH,CECR2,CNTRL,GRIK4,FAM107A,HAS2,NEGR1,HSPA1L,KCNMA1,KHK,KIF5C,MAT2A,MEIS2,MEST,POC1B,MMP16,MSI1,FXYD6,NCAM1,NELL1,NFIX,NME4,NPY,CNTN3,PRTG,PDE3B,ENPP2,PENK,SMOX,FAT3,PPP1R1A,EPDR1,MDGA2,ELOVL2,SPDL1,PTN,ZCWPW1,RBBP6,TSPY26P,NUDT11,RAVER2,ROBO2,TMEM100,UEVLD,PRR5L,HUNK,ZNF354C,SALL1,FAM19A1,SCG5,SLC1A3,SLC4A3,SLC12A2,GKAP1,LIMCH1,CMTR2,NPAS3,SULF2,NUDT10,CAMTA1,CUX2,TRIM2,PCDHB9,PCDHB3,HEY1,TMOD1,TPM2,CADM1,NDRG4,LAMP5,SLC38A1,SIGLEC10,FZD3" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_100_k2 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.00E-04 1.00E+00 1.01E-03 9.16E-03 13 28 "PNMA8B,BACH1,RUNX1T1,ZEB2,GRM7,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,FLRT2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.00E-04 1.00E+00 1.01E-03 9.16E-03 13 28 "CDH10,EBF1,SEMA3D,ELAVL2,GLRB,KCND2,PDGFRA,PIK3R1,FAT4,CSRNP3,FAM19A1,ANO4,TEX15" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k4 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.04E-04 1.00E+00 1.02E-03 9.33E-03 29 91 "ADCY5,ATP1A2,ATP2A2,CACNA2D1,AKAP6,CPEB2,DTNA,ABCC9,NCALD,MRVI1,FHL1,CAP2,SORBS1,DKK3,KCND3,KCNF1,MBP,PDE4D,PRKCB,TTLL7,SCN7A,RIMS1,SYN2,NACC2,SYNPO2,PLSCR4,RGS7BP,FAM13C,MSRB3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.04E-04 1.00E+00 1.02E-03 9.33E-03 29 91 "FMNL2,KLHL13,NR0B1,ATP2B3,CALB1,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,CDON,DRP2,KLHL5,EMX2,GABRA4,PCDH11X,KLHL23,CCDC80,MYO9A,NFIA,ZFHX4,LGR4,HUNK,RASA3,SLC4A3,UHRF1BP1L,ADGRL3,ZFPM2,ACTR6" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000_K4 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 2.05E-04 1.00E+00 1.02E-03 9.34E-03 32 104 "ERMN,ATP2B1,INA,RRAGB,TUBB4A,OLFM1,FGF11,JPH4,GLDC,TOX3,CECR2,SHISAL1,CD200,CCDC80,NRCAM,PDE1A,CEP97,EMID1,SALL1,MAPK12,NTNG1,SMARCA4,BEX1,ADAMTS17,MTCL1,WWC1,WSCD1,WASHC4,BEX4,TST,SLAIN1,FLRT1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.09E-04 1.00E+00 1.05E-03 9.52E-03 20 54 "SPARCL1,ALCAM,ARHGAP20,EDNRA,EGFR,FABP7,GFRA2,FREM1,GLI2,GUCY1A1,IGF1,PCDH9,PDGFRA,FAT3,LAMA1,TMEM255A,ROBO2,MEG3,PEG10,VSNL1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k3 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.09E-04 1.00E+00 1.05E-03 9.52E-03 23 66 "LCORL,DCLK1,NCOR1,TOX,SPOCK3,EPHA5,SCML2,FOXF2,DNER,GLRB,LPAR4,GRIA2,IFI16,KCNA4,PCDH8,PRRX1,TMEM255A,CSRNP3,LRRTM4,ADGRL3,TBX15,CBLN2,SOCS4" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.14E-04 1.00E+00 1.07E-03 9.75E-03 162 761 "SLC12A5,USP31,ADRB2,HECW2,ADGRF5,SHROOM2,ARRB1,ARRB2,NRP2,GPR146,ARHGEF7,C1QC,LDLRAD4,CA8,CANX,LDB2,CD86,SCARB1,CD38,CHN2,MS4A7,QKI,MAP4K4,LY86,ARHGEF6,RBM39,CRMP1,HAPLN1,CSF1R,PPP1R16B,CX3CR1,CYBB,KIF26A,RASSF2,SIRPA,ZEB2,ELMO1,SACS,RABGAP1L,FAM107B,CCDC3,DNM2,ABCC9,SEZ6L2,EDNRB,EBI3,CALCRL,EPHB1,SLC43A2,IGSF6,RCSD1,TLR7,SIRPB1,F8,CORO2B,DLC1,FCGR1A,FLT1,SMC2,TRIM16,FYB1,FAM184B,ERAP1,GATM,PCDH17,GGTA1P,LYVE1,GPR12,LPAR4,RAPGEF4,PRDM5,NCKAP1L,ICA1,IRF8,IFI16,IGF1,KIT,LIFR,LMO2,VWA5A,SMAD1,PIK3AP1,MAP4,TM6SF1,MEF2C,MEIS2,KITLG,CD200,MSR1,MYO7A,P2RY13,NCF2,NRCAM,P2RX7,PDE2A,PDE4B,GNG2,PFKP,SEMA5B,SCHIP1,KANSL1,PRKCB,RELN,SNRK,PTPRB,PTPRE,PTPRO,PTX3,TMEM255A,SH3TC2,RGS3,RGS10,TMEM206,ATP8B4,PRR5L,MAPK12,SEMA6D,RASA3,SGK1,FAM102A,DOCK10,ST8SIA1,SLA,PREX2,BTBD3,SLC11A1,LIMCH1,ARHGAP26,CLASP2,SAMSN1,THSD1,NEK4,CEP68,RGL1,SLC37A2,TAL1,KLHL4,DOCK9,ARHGAP9,TEK,TF,TIE1,TLR4,ZFP91,ERCC6L2,TNFRSF1B,NPL,TRIO,TRPC3,TTPA,VAV1,WIPF1,AMZ1,GDPD5,ADAMTS9,PLD4,RGS7BP,FAM13C,DOCK8,MSRB3,SOCS4,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_100 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_100 FaceBase_RNAseq 2.20E-04 1.00E+00 1.10E-03 9.99E-03 31 100 "ASCL1,FGF17,INA,SRSF11,LHX2,IGDCC3,ABCG1,ST18,ELAVL4,EMX2,OLIG2,CLVS1,TUBB3,FOXG1,GAD2,SRRM4,GPM6A,PCLO,STMN2,SOX21,FAM107A,IGFBPL1,SHISAL1,NNAT,PAX6,FEZF2,RTN1,LINC00461,SOX2,NR2E1,DPYSL5" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.24E-04 1.00E+00 1.11E-03 1.02E-02 46 168 "ADCYAP1R1,SPARCL1,ALCAM,ABCD2,ARHGAP20,LTBP4,GPAM,CACNA1G,ARHGEF25,REPS2,SLIT2,ABI3BP,SNCAIP,VCAN,ARMCX2,ABCC9,EDNRA,EGFR,LRRC17,DLC1,CHST15,ST6GALNAC3,NEK6,GFRA2,FREM1,GHR,GLI2,GRIA4,GUCY1A1,GUCY1B1,HPSE2,LAYN,PCDH9,PDGFRA,FXYD1,PMP22,FAT3,SH3KBP1,TMEM255A,ROBO2,PDZD2,SULF2,ZEB1,VSNL1,ZNF711,PMEPA1" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.24E-04 1.00E+00 1.12E-03 1.02E-02 176 837 "RALGAPA1,ABR,KLHL32,GRAMD1B,ADORA1,USP31,ALCAM,DOC2A,OGT,SEMA7A,APBB2,EPB41L5,DGKD,PHYHD1,ASPA,RIPK1,KSR1,BMP7,ST3GAL5,OSGIN2,CA4,CACNA2D1,THSD7A,KALRN,CANX,HIP1R,CD38,LRRFIP1,CACNA2D2,CLCN3,ENTPD4,RBM39,RNF14,CRYM,TENM4,PPP1R16B,RIPOR2,ARHGAP24,AIF1L,ZEB2,MAGI2,ALKBH8,SMG7,NTM,TMCC2,ARNT2,KBTBD11,CD99L2,DNM2,USH1C,HEYL,OPTN,EIF5,SRPK3,CALCRL,EIF1,RASGRP2,EPHB1,CDHR1,CD320,EZH1,CORO2B,DLC1,RACK1,ST3GAL6,TESK2,MED12L,FGF1,SPSB4,FGFR1,FLT1,SGIP1,SMC2,PDLIM5,CGREF1,GABRA4,ILDR2,GALC,SALL3,IQGAP2,SRRM4,CPLX2,IGSF5,GFRA1,PCDH17,GGT5,AIFM3,FERMT2,GPER1,GRB10,PARD3B,NR3C1,GRM7,SYNPO,HP,HES5,TUBB2B,ZNF385B,KCNJ16,KIF2A,LMO2,C2orf80,CLEC18A,MAPT,SYT9,KITLG,MSI1,LYRM9,FXYD6,NCF2,OXTR,PDE4B,SERPINI1,PIK3C2A,RETREG1,SCHIP1,PMS2,MBOAT7,IRX1,KANSL1,PKN2,RELN,PTH1R,PTPRD,PTPRO,RIPOR1,RAB3IL1,FAM184A,ZYG11B,DUSP15,REV3L,RGS3,ROBO2,EMID1,LGR4,SALL1,MAPK12,SCN7A,FAM19A1,GALNT10,ST3GAL3,ANKRD6,PREX2,RUFY2,SLC12A2,SNCA,MYCBP2,DDN,APOM,STX1A,TMEM150C,TAF9,CAMSAP2,PDLIM2,WWC1,MGRN1,WSCD1,ARHGEF12,ARHGAP9,TMEM9,HEY1,CBX5,TLR4,ERCC6L2,DAAM2,R3HDM1,RGMB,TRIO,SSBP2,ZNF23,GDPD5,TMEM178A,SEMA3B,NUP214,RNF170,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 2.27E-04 1.00E+00 1.13E-03 1.03E-02 16 39 "MAP7,ELAVL2,ELAVL4,RGS17,EMX2,RRAGB,FGF12,KHDRBS3,FUT9,TPPP3,PCLO,PAX6,FEZF2,SOX2,LMO3,WWC1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.29E-04 1.00E+00 1.14E-03 1.04E-02 54 206 "ADGRF5,SPARCL1,SEMA6A,PRX,MTMR2,LDB2,SCARB1,CD38,ABCG2,CNN3,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,SORBS3,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,GSTM5,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_200 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.34E-04 1.00E+00 1.16E-03 1.06E-02 44 159 "KLHL13,NR0B1,PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,MAGI2,DRP2,EDNRA,PLXNC1,EMX2,NRN1,FLNC,AFF2,GABRA4,GABRB1,FREM1,GUCY1A1,TCEAL6,KCND2,KLHL23,MAP2,KITLG,NFIA,PDE1A,PDGFRA,SERPINI1,PCDH18,PRRX1,TMEM255A,TMEM206,STUM,SLC4A3,SMOC1,ADGRL3,TEX15,ZFPM2,ACTR6,TNNT1,VSNL1,LYPD6,WNK3" Coexpression Atlas GSM538242_500 "Myeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 2.36E-04 1.00E+00 1.17E-03 1.07E-02 93 400 "FMNL2,PTCHD1,ALCAM,SEMA7A,FGD2,APP,SHTN1,CASK,CADM3,ADAM23,ST3GAL5,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,SLC4A8,CSF1R,ATRNL1,CTNND2,USP6NL,CYBB,DOCK4,HDAC9,MYADM,SIRPA,CDON,DSCAM,ARRDC4,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,SIRPB1,FGR,GATM,GFRA2,RAB30,ADAP1,GSN,SLC2A6,FRMD5,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KIT,ASPRV1,ADAM11,AFDN,STK32C,ADAM22,MYO5A,CLEC9A,PFKFB3,CDK14,PLTP,RASGEF1B,PRKCB,PTAFR,PTK2,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SEMA6D,SCN3A,ST8SIA1,SLC8A2,SLC8A1,ARHGEF40,CCDC88A,SAMSN1,RGL1,SULF2,TMEM150C,ADGRL3,KIAA0930,CYB561A3,SLC44A1,DDHD1,TRPS1,VAV2,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4 FaceBase_RNAseq 2.38E-04 1.00E+00 1.18E-03 1.07E-02 51 192 "ABCF1,PCDH19,MAGEE2,ASTN1,BBS2,MPDZ,PROM1,DIRAS1,PTBP2,CDK11B,DIS3L,COG1,NIPBL,SLC4A8,IGDCC3,KIAA0586,JAKMIP2,KLHL5,EMX2,EPB41,NSRP1,WAC,ACSL4,FDFT1,FGF12,SMC2,C15orf41,PCLO,CIT,MFSD2A,KIF5C,LSS,NASP,NFIX,OPA1,DIRAS2,ELOVL2,ARID4A,ZYG11B,CLIP1,CASC3,KIF21A,SPATA7,BDP1,SOX11,SYNE2,ARHGEF12,BHLHB9,ZKSCAN5,USP1,HNRNPA3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.38E-04 1.00E+00 1.18E-03 1.07E-02 51 192 "ADGRF5,SPARCL1,SEMA6A,PRX,MTMR2,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_500_k2 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.41E-04 1.00E+00 1.19E-03 1.08E-02 26 79 "PDE8B,BMPR1B,CALB1,RGN,LRBA,B4GALT6,FAM149A,IPCEF1,TENM1,EMX2,GFRA1,PADI2,KCNJ10,KCNK1,L1CAM,VWA2,MAPK4,RASGRF2,VEPH1,RET,PRR5L,SCN8A,LINC00461,HKDC1,RPRM,EMX2OS" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Fetal Endothelial_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Fetal Endothelial_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.47E-04 1.00E+00 1.22E-03 1.11E-02 57 221 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNOT8,ABCG2,CNN3,CDC42BPB,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,LPAR6,PLEKHA1,CALCRL,ARMCX1,FAM198B,FLT1,TRIM16,PCDH17,LYVE1,STMN2,MAP4K5,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Fetal Endothelial_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Fetal Endothelial_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.47E-04 1.00E+00 1.22E-03 1.11E-02 57 221 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNOT8,ABCG2,CNN3,CDC42BPB,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,LPAR6,PLEKHA1,CALCRL,ARMCX1,FAM198B,FLT1,TRIM16,PCDH17,LYVE1,STMN2,MAP4K5,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_200 dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.47E-04 1.00E+00 1.22E-03 1.11E-02 45 164 "NR0B1,GAS7,LGR5,CADPS,CALB1,RGN,SLC16A4,CDH10,DCLK1,DOCK4,DAPK1,SCRN1,DCT,DRP2,MRO,EMX2,MTSS1L,NRN1,PTK2B,CAMKK2,GABRA4,GATM,PPARGC1A,PCDH11X,GPR37,KCNH1,KLHL23,MATN2,KITLG,PDGFRA,RBBP8,REV3L,LGR4,ST8SIA1,SLC4A3,UHRF1BP1L,SPP1,SMOC1,LRRC4,ADGRL3,ZFPM2,ACTR6,FNDC5,ADAMTS9,WNK3" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_500 kidney_P3_CapMes_Crym_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.49E-04 1.00E+00 1.22E-03 1.12E-02 87 370 "NDRG2,KLHL32,RNF157,MTUS1,PCDH19,ALCAM,AMPH,VAT1L,ADAM23,BARD1,BCL7A,CACNA1G,CA4,CA12,CACNA2D1,CACNB4,CDH2,SLIT2,CLU,CLIP3,CRYM,SNCAIP,TENM4,VCAN,CTH,CENPL,SPOCK2,GSDME,SNAP91,SV2B,RAB39B,EDNRA,HSD17B14,KCNMB2,EYA1,ST3GAL6,FGFR1,SCARA3,MTHFD2,IGSF5,GFRA1,KDM2B,TDRKH,CECR2,FAM107A,HAS2,NEGR1,KIF5C,CLEC18A,MAT2A,TM6SF1,MSI1,ADAM22,MYO6,NCAM1,NME4,NPY,CNTN3,PDE3B,PENK,FAT3,MDGA2,PTN,PTPN13,RAVER2,ROBO1,TMEM100,GLDN,PRR5L,SALL1,SCN2A,CNKSR2,SLC15A2,SOX11,TMEM150C,TACR1,CUX2,TRIM2,PCDHB9,AKTIP,HEY1,HEY2,CADM1,LAMP5,SLC38A1,ADAMTS9,FZD3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.49E-04 1.00E+00 1.22E-03 1.12E-02 17 43 "ADAM23,CHRDL1,ABCC9,PCOLCE2,EFEMP1,KCNA1,IL17D,PDE4B,PTPRZ1,TTLL7,RYR3,SLC14A1,SYN2,TIMP4,SYNPO2,AGMO,FAM13C" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_500 dev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.50E-04 1.00E+00 1.23E-03 1.12E-02 96 416 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,ADAM15,NRP2,ARHGEF7,C1QC,LDB2,FMNL3,CD38,MS4A7,JAM2,ABCG2,LY86,HAPLN1,CSF1R,CYBB,DOCK4,KIAA0513,RASSF2,PITPNC1,ELMO1,EBF1,EDNRB,LPAR6,PLEKHA1,CALCRL,PLEKHO1,RASGRP2,FAM198B,CORO2B,DLC1,KIAA1109,FLT1,PDLIM5,FYB1,FYN,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,RAPGEF4,MAP4K5,MAEL,ICA1,IGF1,KIT,INSYN2,LMO2,TM6SF1,MEF2C,KITLG,LAYN,OPHN1,PDE2A,PDE4B,ABCB1,SPATA6,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,RASA3,SGK1,FAM102A,MAGI3,PREX2,BTBD3,LIMCH1,THSD1,PLCB1,KLHL4,TCF4,DOCK9,TEK,TF,TIE1,HEY1,TJP1,DCBLD1,RFTN2,WIPF1,ZNF711,ADAMTS9,NAV3,FAM13C" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.52E-04 1.00E+00 1.23E-03 1.12E-02 25 75 "AMPH,EPB41L5,VAT1L,CASK,ATP1A2,CDH2,CRYM,ELAVL4,CDHR1,EYA1,GABRA1,DENND2A,GRM3,FAM19A2,FAM107A,HAS2,LSAMP,MEIS2,NELL1,SALL1,CSRNP3,ANKRD6,SLC1A3,TTPA,NETO2" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k3_1000 kidney_P1_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.52E-04 1.00E+00 1.23E-03 1.12E-02 25 75 "ASIC2,MTUS1,TXNDC16,CC2D2A,ALCAM,CASK,ADAM23,BCHE,IL33,ABI3BP,AKAP12,SPOCK2,ARRDC4,EXTL2,WASF3,GLRB,ADAMTS6,MMP16,NFIX,NPR2,PENK,NPAS3,SULF2,TPM2,SSPN" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.54E-04 1.00E+00 1.24E-03 1.13E-02 53 202 "SNX32,ADGRF5,SPARCL1,SEMA6A,MTMR2,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,SORBS3,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBB2A,NPDC1,TUBA1A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k1 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.56E-04 1.00E+00 1.25E-03 1.14E-02 34 114 "HECW2,RNF182,LDLRAD4,RUNX1T1,RCBTB2,ZBED5,HAPLN1,BRINP1,ETV1,TMEM132C,CORO2B,FOXF2,SPECC1,MEGF10,GABRA4,GABRB1,PCDH17,B4GALNT4,NEGR1,IFI16,KCNK2,RSPO2,NAP1L2,NDP,DDR2,PCDH18,ZFHX4,C12orf49,TRA2B,LIMCH1,NPAS3,TMPO,TRO,RPRM" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.58E-04 1.00E+00 1.26E-03 1.15E-02 36 123 "ABAT,LGR5,RGN,SLC16A4,CDO1,QKI,VCAN,CTNND1,DCT,SIDT2,SORBS3,MTSS1L,FAM198B,CAMKK2,PPARGC1A,GPR37,LRRTM3,KCNK2,MATN2,PDGFRA,PPP3CC,PRKCB,REV3L,RNASE1,TMEM206,SOX6,ST6GAL1,ST8SIA1,SOX5,SMOC1,FGD4,OBSL1,ZFPM2,TST,SLC38A1,WNK3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K5 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 2.68E-04 1.00E+00 1.31E-03 1.19E-02 31 101 "ATM,BCHE,CBLN1,INA,CLCN3,LRRC3B,G3BP2,ST8SIA3,REEP2,TUBB4A,CEP78,CSDC2,CECR2,SHISAL1,PRTG,NLGN3,MAGEL2,NKAIN4,RELN,PTPN13,CCDC40,BAALC,STK32B,SALL1,PKNOX2,SNRPN,PDZRN3,WASHC4,ZIC2,ZBTB16,SLC38A1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k3 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.69E-04 1.00E+00 1.31E-03 1.20E-02 28 88 "EMILIN3,ADRB2,TMEM263,ATP2B1,MYOM1,CNTN1,COL9A1,PLCXD3,NCALD,CAP2,SORBS1,PNMA2,DKK3,MEGF10,GFRA2,LIMS1,HECTD2,MEIS1,NPTX2,CNTN3,PCDH9,NALCN,LGI2,SH3BGR,SMOC1,HHIP,TPM2,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.72E-04 1.00E+00 1.33E-03 1.21E-02 44 160 "EPB41L5,CD38,CNTN1,COL9A1,CX3CR1,IGSF6,CDHR1,SIRPB1,MRVI1,F8,ST3GAL6,DACH2,FYB1,DKK3,ILDR2,IGSF5,FREM1,NEGR1,KCNA1,KCNC2,KCND3,CLEC18A,TM6SF1,MSR1,CLDN11,OXTR,PENK,PTPRB,PTPRO,PTX3,PRR5L,SALL1,SCN7A,SH3BGR,ANKRD6,SLA,DDN,NEK4,TMEM150C,ANO4,HEY1,TLR4,NPL,SYNPO2" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Subtype Migrating Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Subtype Migrating Myofibroblast Lungmap CCHMC 2.73E-04 1.00E+00 1.33E-03 1.21E-02 96 417 "CLK4,ACTN1,WDR35,C1QTNF1,FAM135A,ANK2,EP400,APBB1,TNRC6C,RGS20,EIF4G3,ATP1B3,MPDZ,FMNL3,MAGI1,NOG,TENM4,MICAL2,CSNK1E,GREB1,GPSM1,CEP170,SNAP91,USP3,CD99L2,RCAN1,FIS1,GOLT1B,BSCL2,CALCRL,COQ7,AMOTL2,SGIP1,TMEM175,USP16,FAM49B,USP21,CAMKK2,ATP6V1H,MSANTD4,ZMYND11,GHR,PRDM5,ZHX1,GABARAPL2,CPT1C,IDH3A,ITGAV,KCNN2,LAMA2,PAXBP1,ZFYVE27,MARK1,LDLRAD3,NUCB1,PENK,PGAM2,CCSER2,PKM,STRN3,PPARA,MED1,PPP2R5C,KANSL1,NDUFS7,BCAS3,PTH1R,TMEM231,LGR4,FNDC3A,DZIP1,SIRT2,TRIM67,TET1,IFT122,SOX5,ERC1,KIF1B,SS18,PHLDB1,STX1A,GANAB,PLCB1,TCF7,TIMP4,TPM3,TPM4,TRIO,RFTN2,ZKSCAN5,VSNL1,INTS3,TUBA1A,FZD3,RSPRY1,MSRB3" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_500_K3 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 2.76E-04 1.00E+00 1.34E-03 1.22E-02 39 137 "ADCY2,CCDC85A,ARHGAP20,CDK10,DACT3,ADGRB2,ZNF599,LRBA,REPS2,CDO1,CRLF1,IGDCC3,CSF1R,CCDC3,DUSP9,ELN,LRRC17,FCGRT,FYB1,ZNF276,SYNPO,IL11RA,MITF,CD200,RSPO2,NFIA,NFIX,CLEC9A,CNTN3,PLCL1,ZMAT4,ATXN1,ACSBG1,ZFR2,ADGRL3,PHF24,TSPAN11,PMEPA1,PCDH15" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-vs-M DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-vs-M_top280_280 Gudmap Mouse MOE430.2 2.78E-04 1.00E+00 1.35E-03 1.23E-02 65 261 "AXIN2,RNF150,ANK2,CDC14B,RASL11B,DYNLL1,BLM,CDK5R1,LARGE1,CLGN,AKAP7,SLC4A7,SLC35F1,FAM171B,TENM4,RIMS2,CENPL,SCRN1,PITPNC1,DCT,RHOBTB1,RABGAP1L,ARNT2,ANKRD46,TBC1D16,TESK2,SCARA3,GABRA1,CHL1,GAD1,FAM120B,FREM1,PPARGC1A,GLI2,GRM3,SYNPO,CELF5,GPR155,PPM1L,NDP,NEK1,VWA2,PFKFB3,SLC22A23,PEX2,TUG1,SEC61A2,SGK1,PPM1E,FRMPD1,DZIP1,ATF7IP,RIMS1,KIF1B,CLSTN2,ZC3H4,SYNE2,CAMTA1,FBXL16,TIMP4,ASXL3,SYNPO2,WNT7A,FMN2,CERS6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte A_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte A_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.81E-04 1.00E+00 1.36E-03 1.24E-02 66 266 "SNX32,SPARCL1,CDC42BPA,MAP4K3,APBB2,APP,CD81,CDH2,CHN1,NRXN1,ARHGEF6,CNRIP1,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,TUBB4A,DLC1,SGIP1,HIGD1B,GNAS,FERMT2,FAM107A,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAP2,MEST,CCDC80,N6AMT1,PDE3A,ENPP2,PCDH18,SEPT4,NKAIN4,PRKAR1B,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,SOX11,MYCBP2,DBNDD2,CLSTN2,TNS2,TRO,CADM1,VSNL1,CLDND1,TUBA1A,TMEM178A,ADAMTSL3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte E_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte E_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.81E-04 1.00E+00 1.36E-03 1.24E-02 66 266 "SNX32,SPARCL1,CDC42BPA,MAP4K3,APBB2,APP,CD81,CDH2,CHN1,NRXN1,ARHGEF6,CNRIP1,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,TUBB4A,DLC1,SGIP1,HIGD1B,GNAS,FERMT2,FAM107A,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAP2,MEST,CCDC80,N6AMT1,PDE3A,ENPP2,PCDH18,SEPT4,NKAIN4,PRKAR1B,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,SOX11,MYCBP2,DBNDD2,CLSTN2,TNS2,TRO,CADM1,VSNL1,CLDND1,TUBA1A,TMEM178A,ADAMTSL3" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000_k5 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.85E-04 1.00E+00 1.38E-03 1.26E-02 42 151 "PNMA8B,PKP4,BACH1,SGCE,SRSF11,CHM,NMT2,RBM39,TENM4,ZC3H11A,EDNRA,EIF4G1,CALCRL,EMX2,EPB41L2,SRRM1,SMC2,APOPT1,ILDR2,LPAR4,NR3C1,CHIC1,MMP16,NASP,CNOT4,NALCN,PIK3R1,PLEC,TMLHE,SLC12A2,ZC3H13,PRRC2C,SYNE2,PCDHB9,CBX5,R3HDM1,TSC1,SSBP2,UBE3A,ADAMTS9,NAV2,GAN" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_k2_1000 kidney_adult_RenCorpuscGlomer_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.85E-04 1.00E+00 1.38E-03 1.26E-02 58 227 "C1QTNF1,EPB41L5,APLP1,UPRT,TMEM108,B3GALT2,THSD7A,MYOM2,SNCAIP,DOCK4,ARHGAP32,ARHGAP24,AIF1L,SIRPA,MAGI2,TSPAN5,OPTN,CEP85L,TLR7,ACSL4,CORO2B,ST3GAL6,SGIP1,ST6GALNAC3,GABRA4,ILDR2,GALC,IQGAP2,MALT1,PARD3B,RASSF8,SYNPO,ZNF385B,ITGAV,MYO6,PDE4B,SLC36A4,FA2H,LRRC49,MDGA2,PTH1R,PTPRO,RIPOR1,RAVER2,ROBO2,ST6GALNAC6,SLA,FAM81A,DDN,KANK1,TMEM150C,PSD3,FRYL,DAAM2,SGK3,PLEKHH2,SYNC,CERS6" Coexpression Atlas facebase_RNAseq_e8.5_FloorPlate_2500_K3 facebase_RNAseq_e8.5_FloorPlate_2500_K3 Gudmap RNAseq 2.88E-04 1.00E+00 1.40E-03 1.27E-02 273 1374 "ABCF1,ARID1A,SLC12A5,KIAA1211,ZNF608,NME5,CEP126,AMPH,PHF12,CNIH2,APLP1,UPRT,VAT1L,ARHGAP5,ARHGDIG,ARRB2,CAPRIN2,PTCH2,ATM,KIF1A,BARD1,BCHE,BID,PROM1,FUBP1,OSGIN2,WASF1,MYRF,CA12,THSD7A,HAP1,PTBP2,BRSK2,MTMR7,ARHGEF1,CDK11B,CDC27,CDH2,ZMYM4,LRRFIP1,CCPG1,TBRG4,CACNA2D2,CBARP,PPT2,CLCN3,KIAA1549L,FAM19A5,C4orf33,QKI,CNTFR,SLC4A7,IFFO1,BAG4,NECTIN3,ZNF385A,SLC35F1,FAM171B,AKAP12,CRMP1,HAPLN1,CLIP3,FAM169A,CTH,GREB1,KATNAL2,TMEM170A,TOMM20,RUSC2,DDX46,POM121,DLG3,CASP8AP2,DPP6,FAM78B,DUSP9,E2F5,SEZ6L2,EDN1,EFNA3,YAF2,LPAR6,EML1,PAN3,EPHB1,SRRM1,NCALD,RTN3,CEND1,EXTL2,CD320,REEP2,WAC,CEP78,PRMT5,OLFM1,POLR1B,SPSB4,AMOTL2,FHL1,IQCG,FOXM1,FLNC,NOP56,SYT3,COQ5,CINP,SMC2,USP21,PRELID3A,PHYHIPL,MTHFD2,GART,WASF3,GATM,CSDC2,GGT7,TCERG1,DBF4,GLI2,TOX3,KIAA1958,GNAO1,GNG3,PSRC1,GPD2,GPR19,LPAR4,STMN2,RABL2A,PSIP1,HSF2,HSP90AA1,LRRCC1,LRRTM3,KIF2A,IPO5,KTN1,CAMK2N2,LSAMP,MAOB,MAT2A,AQP11,MEST,PPM1L,ADAM22,MDGA1,MYCN,LINC00672,NAP1L1,NASP,RCOR2,CNOT4,NOVA2,CLDN11,PAK3,PDCD2,TMOD2,FAM98B,OLA1,PFKP,PIK3CD,SNX10,RETREG1,PKM,SLC25A23,PRIMPOL,PMP22,FAT3,FSD1,PPP1R1A,NKAIN4,PRKCB,MASP1,RELN,LAMA1,GDPD2,PTCH1,UHRF1BP1,ZIK1,PTPN13,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,PRRT2,ERI2,MORC4,FIGN,RFX3,NUDT11,LGI2,SETD5,MYH14,RAVER2,ROBO1,RPL15,KIAA0895L,RIMKLA,HUNK,KCNIP3,YJEFN3,SALL1,MAPK12,LRRTM4,FAM19A1,SOX6,TRIM46,ASRGL1,KIF21A,NTNG1,FHOD3,CCDC92,ANKRD6,ZNF365,PKNOX2,SHANK2,SLC20A2,TET1,PDZD2,SOX5,SOX11,SPTB,RBM26,PBLD,POGZ,LARP4,LRRC4,NEK4,SEPT3,SYT11,ANKRD28,MTCL1,CUX2,TCF7L2,SIRT1,C18orf54,ITGB3BP,TJP1,HEY2,PRMT8,STXBP4,TST,CADM1,EIF4ENIF1,AMOT,SLAIN1,USP1,MEAF6,CCDC14,LMF1,XPO1,ZNF23,ZFP41,ZNF184,SMARCAD1,EMSY,SHD,SLC38A1,RGMA,STOX2,TUBA1A,NAV2,WNK3,AMN1,FZD3,SMIM8,PHTF2,AAAS,NETO2,SPATA13" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 2.89E-04 1.00E+00 1.40E-03 1.27E-02 75 311 "NDRG2,PLEKHG5,ERMN,PTCHD1,C1QTNF1,APOC1,MAP7,INA,MYL6B,LRRC3B,HDAC9,MYADM,SPOCK2,SEMA3D,EGFR,RRAGB,CEND1,TUBB4A,FGF11,SYT3,JPH4,SALL3,STARD10,PCDH17,CSDC2,GLDC,CECR2,PSIP1,FAM107A,FRMD3,HMGCL,TCEAL6,CDH20,KCNK1,KHK,MATN2,IL17D,MEIS1,MOV10,CCDC80,HS6ST3,IGSF11,PRTG,GPR173,PENK,FXYD1,MAGEL2,NKAIN4,TSPY26P,EMID1,LGR4,SALL1,FERMT1,CLSTN1,SLC4A3,PALLD,SOX2,DOK5,UNC5B,INKA2,AJAP1,ADAMTS17,ROBO3,MCF2L,WWC1,WASHC4,TEX15,TNNT1,SLAIN1,CCDC136,PORCN,ZIC2,NDRG4,CA10,PIANP" Coexpression Atlas JC_iEC_1000_K5 JC_iEC_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 3.00E-04 1.00E+00 1.45E-03 1.32E-02 87 372 "ASIC2,PLEKHG5,SLC44A5,KLHL13,CASKIN1,PCDH19,OSBPL6,BBOX1,AMH,ST3GAL5,MYRF,CACNA1E,CALB1,CH25H,NEURL1,DGKI,CDH10,LGI1,NOG,SYNPR,TMEM155,DCC,C8orf34,CNIH3,MFAP3L,GRIN3A,DPP6,MAMLD1,TMTC1,TENM1,EN2,F3,FOXG1,PNMA2,HHIPL1,NRG3,ILDR2,GAP43,DNER,GBX2,LNX1,MCHR1,STMN2,GRM7,BVES,ARHGAP36,SAMD5,NDP,NELL1,NRCAM,OPCML,SNTG1,PCDH9,PCSK1,PCSK5,PDE4D,TRHDE,FA2H,PTHLH,RPE65,TMEM100,SOX8,ST6GAL1,LRRC55,CXXC4,OGDHL,SOX1,SPP1,ITPRID2,ARC,POPDC3,KLHL4,ANO4,TBX15,PCDHGB6,PCDHGB2,ARL10,ASXL3,TRH,TRPS1,VLDLR,TRIM9,CELF4,LAMP5,TMEM178A,NETO2,ST8SIA2" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 3.03E-04 1.00E+00 1.46E-03 1.33E-02 124 564 "CLK4,ADD3,FAM135A,PKP4,APC,API5,ARHGAP5,BBS2,SLC16A4,SEPT7,SRSF11,EPS15L1,ZFYVE9,COG1,HECTD1,CNN3,SLC4A7,TBPL1,IGDCC3,CSNK1G3,DZIP3,PNPLA8,TBC1D5,KIAA0586,YTHDC1,KIAA0753,CEP170,ZC3H11A,GNE,DYRK1A,DNM1L,E2F6,EDIL3,KLHL5,EIF5,MRNIP,COQ7,MTSS1L,SRRM1,NSRP1,WAC,KAT8,SEC24B,KIAA1109,ZCCHC17,ST6GALNAC3,OGA,CAB39,RAPGEF6,C15orf41,ARFIP1,NFU1,DBF4,GOLGB1,ADGRA3,DIDO1,ZHX1,ATXN2L,HMGB1,HSF2,LIMS1,MARK3,MEST,RSPO2,NEK1,ODF2,PDE3B,FAM98B,PRIMPOL,EXOSC10,CEP41,RIPOR1,PPP2R3C,ARID4A,ZYG11B,SETD5,GSTCD,ELP2,CLIP1,SCP2,TRA2B,CHD9,FNDC3A,EPN2,SEPHS1,ZNF334,CDK5RAP2,SPATA7,BDP1,CAND2,UHRF1BP1L,MYCBP2,ZNF423,ZC3H13,RBM26,LARP4,MPRIP,NEK4,STXBP1,DNAJC9,TAF9,FAM208A,TBL1X,TCEA1,ZEB1,DICER1,SIRT1,AP4E1,TMPO,TRIO,TRO,ZKSCAN5,XPO1,ZNF711,ZNF142,ZSCAN26,ZFAND5,WNK1,MAP3K12,CSDE1,KAT6A,HNRNPA3,JMJD1C,ZDHHC20" Coexpression Atlas gudmap_developingGonad_P2_testes_500 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.06E-04 1.00E+00 1.47E-03 1.34E-02 94 408 "TTYH1,ACLY,TKTL1,ARID1A,TMCC3,ADCYAP1R1,ADD1,ADORA1,NR0B1,C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,MMD2,BTRC,DDR1,CALM1,VXN,CBLN1,SCARB1,ADGRG1,JAM2,CLU,FADS2,RBM39,RNF14,ARHGEF4,PUM1,ARHGAP32,TOX,SPOCK2,DBI,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,RASL12,REEP2,TUBB3,SCML2,FGFR1,DPYSL4,FYN,GATM,GPM6B,GPR37,GRB10,MAEL,HSD17B1,IL6ST,TUBB2B,JAK1,TTYH2,MEF2C,NRBP2,MT3,MYO7A,NEXMIF,NFIX,NNAT,PAK3,PDGFRA,SEMA5B,PLP1,PTPRE,TMEM206,MEG3,SOX8,SH3GL2,ARX,SLC1A6,EFHD1,ZCCHC24,ACSBG1,PUM2,HHIP,TST,SGK3,UCHL1,USP1,ZFAND5,VPS35L,PCBP4,RTN4" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_500_K5 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 3.09E-04 1.00E+00 1.49E-03 1.35E-02 13 29 "KLHL32,BMPR1B,CDC25B,SRSF11,LHX2,IGDCC3,ST18,EIF5,GRIK2,ODF2,PDE3B,GSTCD,ZFP2" Coexpression Atlas BM Top 100 - pituitary gland BM Top 100 - pituitary gland Body Map 3.17E-04 1.00E+00 1.53E-03 1.39E-02 25 76 "KIAA1324,SYT13,ASCL1,BAIAP3,CHGA,CHGB,CNR1,CALY,PCOLCE2,PCSK1N,GNAS,ARHGAP36,IGSF1,INSM1,NNAT,NPTX2,KSR2,PCSK1,VEPH1,MEG3,SCN3B,PEG10,SCG2,LINC00632,SLC17A6" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_500 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.21E-04 1.00E+00 1.54E-03 1.41E-02 16 40 "KLHL13,ARHGAP20,AKAP5,ZNF521,SRGAP3,AFF2,NSG1,TCEAL6,KCND2,MAP2,CCDC80,NFIA,PDE1A,PCDH18,CNTLN,SCMH1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.21E-04 1.00E+00 1.54E-03 1.41E-02 16 40 "CACNA2D1,CFL2,VCAN,SYNCRIP,SMC2,PDLIM5,FERMT2,MKLN1,NFIA,PIK3C2A,KANSL1,REV3L,ERCC6L2,RBFOX2,RGMB,SSBP2" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k4_500 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.24E-04 1.00E+00 1.56E-03 1.42E-02 39 138 "GAS7,MARK4,ATP1A1,DST,ST3GAL5,RGN,ADGRG1,SCRN1,DCT,DTNB,SIDT2,SORBS3,ERBB2,FAM198B,CAMKK2,PPARGC1A,ADGRA3,GPR37,KCNH1,KCNK2,NCOA7,MAN2A2,MSI1,NRBP2,CTNNA3,FXYD6,NELL1,PRKCB,SH3TC2,ROBO1,GLDN,RPS6KA2,MRAS,DOCK10,ST6GAL1,SPP1,ADHFE1,SLC38A1,ADAMTS9" Coexpression Atlas GSM777043_500 "Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3" "Immgen.org, GSE15907" 3.31E-04 1.00E+00 1.59E-03 1.45E-02 101 445 "SERPINA3,FMNL2,ADCYAP1R1,PCDH19,ADGRF5,SPARCL1,SRPX,LTBP4,CDC42BPA,ANK2,APBB2,APP,MPDZ,NRP2,SGCE,IL33,CACNA2D1,CD81,DCLK1,SLIT2,FADS2,MAGED1,ABI3BP,CP,AKAP12,CSF1,LRIG1,ATRNL1,VCAN,CTNND1,DNM1,ECM2,ABCC9,EBF1,EDNRA,EGFR,CALCRL,EPS8,ETV1,F3,ABCA8,FAM198B,EFEMP1,DLC1,FGFR1,FHL1,TPPP3,DENND2A,NCKAP1,GFRA2,GHR,FERMT2,GPM6B,GRB10,GSN,GUCY1A2,HAS2,DOCK7,LAMA2,LIFR,MATN2,MEIS1,KITLG,CCDC80,NBL1,NFIA,NPR2,DDR2,P2RY1,PDGFRA,ENPP2,CDK14,SERPINE2,PCDH18,PMP22,PRRX1,PTN,PTPRG,RET,ROBO1,KIRREL1,SCN7A,BTBD3,PDZRN3,ST5,SYNE2,TCF4,ARHGEF12,TNS2,TGFBR3,TJP1,TLR4,CSMD1,IL34,RGMB,SYNPO2,FLRT2,PLEKHH2,AGMO,ADAMTS9,ADAMTSL3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K3 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 3.32E-04 1.00E+00 1.59E-03 1.45E-02 60 238 "EMILIN3,AMPD2,IGDCC4,CACNA1G,GPC2,CACNA2D1,CDO1,PCYT1B,COL9A3,CLIP3,SNCAIP,DGKG,C8orf34,ACOT8,ELN,FDFT1,BAIAP2,ZMYND15,SGIP1,NBEA,TMEM151A,JPH4,HIGD1B,ZNF276,RAB30,RAPGEF4,WIF1,HLF,IGF1,KHK,VWA5A,SMAD9,CD200,CPNE9,N6AMT1,TCEAL5,NFIX,NPY,CNTN3,PDE1A,PDE4D,PENK,PFKFB2,DIRAS2,ACSS3,RAP1GAP,MYH14,TMEM100,DGLUCY,CNKSR2,DZIP1,ARHGAP26,ARHGEF9,ADGRL3,PHF24,HIF3A,LEFTY2,STXBP4,PMEPA1,CERS6" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_500 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.34E-04 1.00E+00 1.60E-03 1.46E-02 94 409 "HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,SHROOM2,NRP2,ARHGEF7,C1QC,CA8,LDB2,FMNL3,CD38,ABCG2,LY86,ARHGEF6,ZNF521,CRMP1,HAPLN1,CSF1R,CX3CR1,CYBB,PITPNC1,ELMO1,FAM107B,CCDC3,EBF1,EDN1,EDNRB,LPAR6,PLEKHA1,CALCRL,PLEKHO1,RASGRP2,FLT1,PDLIM5,FYB1,GAP43,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,GPM6A,LPAR4,RAPGEF4,MAP4K5,NCKAP1L,ZDHHC15,ICA1,IGF1,KIT,LMO2,TM6SF1,MEF2C,MEST,MSR1,CLEC9A,OPHN1,PDE2A,PDE4B,SPATA6,RASGEF1B,PROX1,SNRK,MDGA2,PTPRB,TMEM255A,C1orf54,SEMA6D,RASA3,SGK1,MAGI3,PREX2,BTBD3,SLC15A2,LIMCH1,PEG10,SAMSN1,THSD1,KLHL4,TEK,TF,ZFPM2,TIE1,TJP1,TRPC3,RFTN2,TTPA,FLRT2,WIPF1,ZNF711,ADAMTS9,NAV3" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_200 kidney_P1_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.35E-04 1.00E+00 1.60E-03 1.46E-02 35 120 "ALCAM,AMPH,IL33,CACNA2D1,CACNB4,CNTFR,CRYM,SNCAIP,VCAN,PHF19,SPOCK2,SNAP91,ELAVL4,ETV1,EYA1,FGFR1,IGSF5,GFRA1,TDRKH,HAS2,NEGR1,MEIS2,NCAM1,CNTN3,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1,SLC1A3,CUX2,PCDHB9,TPM2,CADM1" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 3.37E-04 1.00E+00 1.61E-03 1.47E-02 54 209 "ACTN2,ADCY2,ADCY8,KIAA1324,ARHGAP20,PDE8B,ADGRB2,BARD1,C1QC,LDLRAD4,CAMK2A,REPS2,KCNAB3,CSF1,CSF1R,DLG2,DRP2,SNX29,RASA4,EPS8,FYB1,ARPP21,TMEM8B,LYVE1,GNG4,GRIA1,ZNF385B,KLHL23,GPR155,NELL1,NPR2,PLCL1,TRHDE,NXPH1,PRKAR1B,MASP1,DEF8,ZCWPW1,ZNF493,ZMAT4,MYH14,STK32B,MRAS,SH3GL2,ASAP3,SLC1A2,SLC6A9,UNC5D,FAM189A1,EML6,CADM2,LRP8,PCDH15,DPF3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.37E-04 1.00E+00 1.61E-03 1.47E-02 54 209 "ADGRF5,SPARCL1,SEMA6A,PRX,MTMR2,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,CALCRL,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SEMA6D,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBB2A,NPDC1,TUBA1A" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_500 dev gonad_e13.5_M_DevVasTestis_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.46E-04 1.00E+00 1.65E-03 1.50E-02 98 430 "NCKAP5,GRAMD1B,HECW2,ADGRF5,SPARCL1,SEMA6A,SEMA7A,APBB2,APOC1,SHROOM2,DDX3Y,DOCK11,NRP2,C1QC,CBLN1,LDB2,FMNL3,SCARB1,CD38,MS4A7,JAM2,CLU,FADS2,ABCG2,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,CX3CR1,CYBB,DOCK4,ARMCX2,ZEB2,ELMO1,EBF1,EDNRB,PLXNC1,PLEKHA1,CALCRL,RASGRP2,FAM198B,ACSL4,DLC1,FLT1,AFF2,PDLIM5,FYB1,FYN,IQGAP2,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,RAPGEF4,MAP4K5,NCKAP1L,ELOVL5,HMGCR,ICA1,KIT,LMO2,LSS,TM6SF1,MEF2C,LAYN,NPY,PAK3,PDE2A,FAT3,RASGEF1B,SNRK,MDGA2,PTPRB,TMEM255A,C1orf54,SLC6A15,ROBO2,SEMA6D,PREX2,LIMCH1,PEG10,THSD1,SMOC1,ACSBG1,KLHL4,TEK,HHIP,TIE1,TJP1,RFTN2,VSNL1,STOX2,NAV3,FAM13C,DOCK8" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.50E-04 1.00E+00 1.67E-03 1.52E-02 168 801 "RALGAPA1,ABCF1,METAP1D,SLITRK1,ADORA1,DOC2A,OGT,ANK3,PKP4,APC,EPB41L5,DGKD,PHYHD1,AQP4,CDC14B,PDXK,PDE8B,PROM1,BMP7,BMPR1B,CA4,CA8,CALB1,CANX,MAP7,RGN,LRBA,CRLF1,B4GALT6,SLIT2,CLCN3,FAM149A,COL9A3,AHCTF1,SLC35F1,RBM39,CRYM,IPCEF1,CNTNAP2,KIAA0040,UBXN2A,CTH,GREB1,CTNND2,FGFR1OP2,ARHGAP24,MFAP3L,DDX46,ARNT2,DUSP9,HIPK3,SEMA3D,EIF5,TENM1,SRPK3,EIF1,EMX2,EPB41,MED12L,KIAA1109,SPSB4,FGF12,SUCO,SYNCRIP,SMC2,PDLIM5,RASL10A,CAMKK2,MPP6,AHCYL1,GALC,IQGAP2,IGSF5,GFRA1,PPARGC1A,MAP7D2,CNDP1,B4GALNT4,CNTRL,GRB10,DIDO1,GRIK2,FRMD5,ICA1,IGFBP1,SCIN,TUBB2B,KCNC2,KCNJ10,KCNJ16,KCNK1,KIF5C,L1CAM,KITLG,MID1,MYH7,NASP,NEK1,VWA2,CNOT4,OCRL,OLA1,PIK3C2A,PLXNB1,PSAT1,MBOAT7,KANSL1,PKN2,MAPK4,LAMA1,EML5,RASGRF2,VEPH1,DPF2,RET,REV3L,PRR5L,EMID1,CLIP1,SALL1,SCN8A,LINC00461,HES6,SOX6,SFPQ,ASRGL1,HKDC1,FHOD3,FAM81A,DHX30,RUFY2,SCMH1,LIMCH1,LRRC4,STX1A,FGD4,PRRC2C,TMEM150C,PJA1,DNMBP,CAMSAP2,WWC1,TBL1X,MGRN1,WSCD1,NSD1,ERCC6L2,R3HDM1,RGMB,ELP5,TRIO,DCBLD1,SSBP2,CADM1,RPRM,UBE3A,UGT8,VLDLR,VSNL1,NSD2,ZNF23,ZNF24,FMN2,EMX2OS,TMEM178A,FIP1L1,PCBP4,NUP214" Coexpression Atlas PCBC_ratio_SC blastocyst_vs_SC-LF blastocyst_cfr-2X-p05 SC blastocyst_vs_SC-LF blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.52E-04 1.00E+00 1.67E-03 1.52E-02 56 219 "TMEM132B,BCL2L2,DIRAS1,LDB2,FOXN3,ZNF385A,FEZ1,RIMS4,PNPLA8,TCAF1,DDX46,CHRDL1,FAM57B,KLHL5,EFNA3,EFNB3,LINC00599,PCOLCE2,ANKRD13B,EFS,ARMCX1,FABP7,NBEA,CAMKK2,DKK3,MEGF10,IQGAP2,ARHGAP19,KIT,LRRC4B,FGFBP3,SESN3,ZDHHC22,PFKFB4,SEMA5B,PCDH18,GDPD2,PTN,PRRT2,EXD2,ROBO1,ST6GALNAC6,ASAP3,FHOD3,KDM3A,IDI2-AS1,RAP1GAP2,ZC4H2,FCHO1,RHBDL3,NUDT10,SYT1,TCEAL7,ZNF138,DPYSL5,SRGAP2B" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.53E-04 1.00E+00 1.68E-03 1.53E-02 27 85 "ADORA1,RASL11B,THSD7A,ARHGAP24,AIF1L,MAGI2,CORO2B,SGIP1,GABRA4,ILDR2,SYT17,IGSF5,GRM7,SYNPO,HP,MAPT,SYT9,SCHIP1,GDPD2,PTPRO,RIPOR1,FAM184A,DUSP15,SCN7A,DDN,TMEM150C,TMEM178A" Coexpression Atlas gudmap_developingGonad_P2_ovary_1000_k2 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.55E-04 1.00E+00 1.69E-03 1.54E-02 69 283 "ADARB2,SLITRK1,TMCC3,PLA2G4C,SEC11C,JAZF1,USP2,ABI3BP,MYRIP,GDA,TENM4,CSNK1E,PHACTR3,PLXNA4,GSDME,SNAP91,G3BP2,SLC12A6,E2F5,ATL1,ELAVL2,MRNIP,EZH1,KAT8,FOXO3,B3GAT1,ILDR2,DNER,GDF9,KIF3A,TOX2,SYNPO,HNMT,SHISA6,KIT,SYTL4,BCO1,RSPO2,NOS1,SETD4,ABCB1,MAPK10,GDPD1,STK32A,SUSD4,RDX,PCMTD2,TRAPPC13,SATB1,FAM19A1,IL17RB,KIF16B,CPEB3,SLC14A1,SORCS3,RIMS1,SRPK2,CLSTN2,SYNE2,CAMTA1,ANO4,MTMR14,PARD3,TBC1D15,TRIM9,NDRG4,FAM47E,FAM13C,DPF3" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_200_k5 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.55E-04 1.00E+00 1.69E-03 1.54E-02 22 64 "PNMA8B,PKP4,ATP2B1,BACH1,RUNX1T1,SLIT2,COL4A5,ZC3H11A,EIF4G1,EPB41L2,LPAR4,GRM7,CHIC1,MEIS1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2,UBE3A,FLRT2" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k3_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.62E-04 1.00E+00 1.72E-03 1.57E-02 32 107 "SPARCL1,ALCAM,ARHGAP20,GPAM,MPDZ,CACNA1G,ARHGEF25,REPS2,ZNF521,HAPLN1,ZEB2,EDNRA,EGFR,LRRC17,ST6GALNAC3,GFRA2,FREM1,LPAR4,GUCY1A1,GUCY1B1,IGF1,LAYN,PDGFRA,FXYD1,FAT3,TMEM255A,ROBO2,PEG10,NPAS3,SULF2,VSNL1,ZNF711" Coexpression Atlas facebase_RNAseq_e9.5_MandArch_2500_K2 facebase_RNAseq_e9.5_MandArch_2500_K2 Gudmap RNAseq 3.67E-04 1.00E+00 1.74E-03 1.58E-02 20 56 "CAMK2A,TMEM59L,IGDCC3,FAM169A,AFF2,RUNDC3A,CECR2,GRIK2,RNF165,PSIP1,KIF5C,NASP,PDE3B,ELOVL2,CCDC40,SOX6,SLIT1,CXXC4,SOX5,ACSBG1" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k5 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.69E-04 1.00E+00 1.74E-03 1.59E-02 59 234 "NDRG2,ADCY8,ADD3,SRPX,ARHGAP20,PTCH2,ATP1A2,ADGRB3,JAZF1,IL33,VSTM2A,LDB2,DCLK1,CP,CRYBB1,PLCXD3,RIPOR2,MFAP3L,CHRDL1,ABCC9,EDNRA,ENO2,ETV1,EFEMP1,FCGRT,FGF1,FUT9,GABRB1,GAD1,TNRC6A,GLUL,HTATSF1,CNDP1,GPM6A,PARD3B,IGFBP1,KCND3,MAOB,MATN2,NFIA,NTRK3,PCSK5,PENK,NALCN,FAT3,PTN,C1orf54,VEPH1,LGI2,MRAP2,ATXN1,WASHC4,PCDHB9,HHIP,TNNT1,RASD2,VLDLR,PMEPA1,RGS7BP" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K4 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.75E-04 1.00E+00 1.77E-03 1.61E-02 53 205 "ACTN2,ADCY2,ARHGAP20,MARCH4,CPNE5,LGR5,ZFYVE28,ATP1A3,ADGRB2,BARD1,C1QC,LDLRAD4,REPS2,KCNAB3,CDH18,CRYBB1,CSF1R,CCDC3,DLG2,FCGRT,NPTN,ABLIM2,FYB1,ARPP21,TMEM8B,GRK4,TMEM25,TCEAL6,IL11RA,ZNF385B,KCNA6,MOBP,MYH3,NEXMIF,PLCL1,NXPH1,MASP1,RALGDS,ZMAT4,MORC4,ATXN1,SH3GL2,DOCK10,SLC1A2,C11orf87,NKAIN2,ZFR2,FAM189A1,KCNE5,CADM2,LRP8,PCDH15,PRRT4" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_1000 kidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.75E-04 1.00E+00 1.77E-03 1.62E-02 182 878 "CPNE2,MTUS1,HECW2,OSBPL8,C1QTNF1,ADGRF5,PI16,APBB2,EPB41L5,APLP1,UPRT,APP,ARRB1,PDE8B,ASPA,DDX3Y,TMEM108,ATP1B3,B3GALT2,CFLAR,CACNA2D1,CALB1,THSD7A,CD38,CD81,MYOM2,JAM2,CLTB,ARHGEF6,CP,CLOCK,ANKRD44,SNCAIP,CSF1,LRRC3B,CST3,KIAA0040,CYBB,DOCK4,ARHGAP32,ARHGAP24,DGKB,AIF1L,SIRPA,PITPNC1,ZEB2,MAGI2,NR1D2,ECM2,EBF1,TSPAN5,EDNRB,HIPK3,TMTC1,FRY,OPTN,IRAK4,EML1,CALCRL,RCAN2,RASGRP2,CEP85L,TLR7,F8,ACSL4,CORO2B,DLC1,ST3GAL6,FGF1,FLT1,SGIP1,UFM1,PDLIM5,NPTN,ST6GALNAC3,GABRA4,ILDR2,GALC,IQGAP2,ERAP1,INPP5K,MALT1,FERMT2,RAPGEF4,STMN2,PARD3B,NR3C1,GUCY1A2,GUCY1A1,GUCY1B1,RASSF8,ZHX1,FRMD3,GABARAPL2,SYNPO,IFI16,IL6ST,INPP5B,ZNF385B,ITGAV,KCNJ16,LIFR,LMO2,VWA5A,MAPT,CD200,CCDC80,MSR1,LAYN,MYO6,NCF2,P2RX7,P2RY1,PDE2A,PDE3A,PDE4B,PDGFRA,SERPINE2,SERPINI1,PIK3R1,CCSER2,PLCL1,SEPT4,SLC36A4,FA2H,MINDY2,PKIA,LRRC49,SNRK,MDGA2,PTH1R,PTN,PTPRB,PTPRO,RIPOR1,PLEKHB2,ZDHHC14,ZMAT4,RAVER2,ROBO2,LRRK2,ST6GALNAC6,WLS,SCN7A,SGK1,DOCK10,SLA,FAM81A,PREX2,SLC12A2,CPEB4,LMBRD1,DDN,COLGALT2,ITPRID2,NXT2,RGL1,KANK1,PLCB1,TMEM150C,ANKRD12,SYNE1,PSD3,ARHGEF12,TNS2,FRYL,TEK,TGFBR3,TIE1,TJP1,TLR4,DAAM2,TNS1,TRPC1,TMEFF2,SGK3,PLEKHH2,SLC26A10,SYNC,PLSCR4,DOCK8,CERS6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k1 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.77E-04 1.00E+00 1.78E-03 1.62E-02 12 26 "PCDH10,EPHA5,EYA1,TMEM132C,FOXF2,SGIP1,WIF1,IFI16,MYH3,ZFHX4,CSRNP3,TAC1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.78E-04 1.00E+00 1.78E-03 1.63E-02 29 94 "FMNL2,NR0B1,PPP4R4,CACNB2,DCLK1,MAGI1,PLXNA4,DOCK4,DAPK1,DCT,DRP2,KLHL5,EMX2,MTSS1L,GABRA4,PCDH11X,KLHL23,KITLG,NFIA,SERPINI1,LGR4,HUNK,RASA3,SLC4A3,UHRF1BP1L,ADGRL3,ACTR6,FNDC5,DPF3" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 3.81E-04 1.00E+00 1.80E-03 1.64E-02 62 249 "EMILIN3,ACTN2,ADCY2,SRPX,ARHGAP20,CDK10,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,ABI3BP,IGDCC3,ANKRD44,CSF1R,CCDC3,DLG2,RASA4,ELN,EPB41L1,LRRC17,FCGRT,FYB1,ARPP21,TMEM8B,ZNF276,GLRB,WIF1,SYNPO,IL11RA,VWA5A,CD200,TCEAL5,NFIX,CNTN3,PLCL1,NXPH1,PRKAR1B,ACSS3,ZMAT4,ZFHX4,MYH14,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC1A2,SLC6A9,ZFR2,UNC5D,ADGRL3,PHF24,FAM189A1,TSPAN11,PMEPA1,CADM2,LRP8,PCDH15" Coexpression Atlas PCBC_ctl_geo-heart_500 geo_heart_top-relative-expression-ranked_500 PCBC 3.88E-04 1.00E+00 1.83E-03 1.67E-02 111 499 "SERPINA3,TKTL1,ACTN2,ADCY5,HHATL,AGT,C1QTNF1,ADGRF5,SPARCL1,ANK1,PI16,MYH7B,DDO,CPNE5,PLA2G4C,ATP1A2,ATP1A3,MYOM1,AZGP1,GPR146,LDHD,C1QC,CACNB2,CAMK2A,CAMK2B,USP2,MYOM2,CHI3L2,LSMEM2,TOGARAM2,CSF1R,PDE4DIP,PLCXD3,CFAP61,DGKG,EEF1A2,SRPK3,RCAN2,DUSP27,RCSD1,F5,ABCA8,FCGR3A,FGF12,FGR,FOLR2,SORBS1,KBTBD12,ABLIM2,IP6K3,HIGD1B,MYOZ2,ALDH1L1,TUBA8,CSDC2,GGTA1P,PPARGC1A,LYVE1,GPD1,GPR17,PLPP7,FAM107A,UBE2QL1,HBA1,FRMD3,INSYN1,HLF,VSIG4,HP,HPR,IGF1,ITGA7,KCND3,KCNK3,MAOB,MT3,MYH6,MYH7,MYL3,NCAM1,NPPA,PGAM2,DUSP26,PHKG1,RETREG1,PLCL1,PLIN1,FXYD1,PPP1R1A,DKFZp779M0652,PYGM,RNASE1,MYH14,SYNDIG1,KCNIP2,SCN7A,ABLIM3,SLC4A3,LIMS2,SLC8A1,SLC11A1,SPHKAP,SLN,FAIM2,IDI2-AS1,SPTB,VWC2,TMOD1,VIPR2,LGI4,SLC30A3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglb_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglb_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 3.89E-04 1.00E+00 1.83E-03 1.67E-02 77 324 "AXIN2,RNF150,SLC44A5,SORCS2,C1QTNF3,C6orf89,RASL11B,ATP1A2,CDC25B,CDH2,CDO1,CDR1,CHN2,CLU,COL4A5,ZNF521,LRRC3B,CNTNAP2,DCAF8,RCAN1,SEZ6L2,ADGRV1,F3,ABCA8,TMEM132C,ZIC4,TMEM107,ERGIC3,GRM8,GSN,WIF1,IGF1,IL11RA,OLFM3,KCND2,LAMA2,LAMP2,MBNL1,LRP1B,KCTD6,RSPO2,NFIA,NFE2L2,NUCB2,CNTN3,PAX6,PDE3A,PDE4B,PFKP,PKM,KCTD15,PLTP,PURG,PRRX1,FAT4,RFX3,MRPS18A,KIRREL1,LGR4,WLS,GALNT10,PUF60,SLC8A1,PALLD,BEX1,SYNE2,TCF12,TEX15,TPM1,ZIC1,ZIC2,FSTL5,MFF,DNALI1,SLC38A1,FAM13C,NHSL1" Coexpression Atlas PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-plasmid_cfr-2X-p05 Ectoderm Differentiated Cells-method_NA_vs_Ectoderm Differentiated Cells-method_plasmid-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.93E-04 1.00E+00 1.85E-03 1.68E-02 31 103 "AXIN2,ADORA1,PCDH10,RASL11B,NRP2,LGI1,NOG,NGEF,NRG2,TENM4,LYPD1,CDON,EDNRA,TMEM132C,ZIC5,ITPKB,KCNA1,CLEC18A,SAMD5,PDE2A,PDE1B,IRX1,ZFHX4-AS1,LRRN3,RFX4,ZFHX4,SLC30A10,SLIT1,TAC1,TMEFF2,DOCK8" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05 ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 3.95E-04 1.00E+00 1.85E-03 1.69E-02 71 294 "AXIN2,ADORA1,ALCAM,PCDH10,DGKD,MARK4,RASL11B,ATP1A2,RIPK1,DOCK11,NRP2,BMP7,CALM1,LGI1,NOG,NGEF,COL9A3,COL11A2,NRG2,HAPLN1,TENM4,PDE4DIP,BOC,DOCK4,LYPD1,CDON,EDIL3,EDNRA,ELAVL2,MTSS1L,TMEM132C,FECH,GAP43,RASSF8,ZIC5,ITPKB,KCNA1,KIT,CLEC18A,MAP2,MATN2,SAMD5,NPY,PDE2A,PDE1B,PFKP,SERPINE2,PLTP,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,PRODH,RELN,PTPRD,RFX4,ZFHX4,SLC30A10,SLC12A2,SLIT1,SOX10,DOK5,NMNAT2,SPP1,COLGALT2,COBL,TAC1,TMEFF2,ZIC2,SEMA3B,DOCK8" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.95E-04 1.00E+00 1.85E-03 1.69E-02 50 191 "KDM5D,AMH,SEMA7A,GAS7,CADPS,DDX3Y,ATP1A1,ALDH7A1,CACNA2D2,ADGRG1,CLU,MAGED1,SCRN1,DTNA,MRO,PLXNC1,EPS8,ERBB4,FAM198B,PTK2B,FGF13,CAMKK2,IQGAP2,GATM,PPARGC1A,ADGRA3,GPM6B,GPR37,DOCK7,KCNH1,PAK3,SERPINE2,RASGEF1B,MASP1,ROBO1,PCMTD2,GLDN,SOX6,MRAS,DOCK10,TNIK,SPP1,TSPYL2,SYNE2,THRA,TIAM1,SGK3,CLDND1,ADAMTS9,WNK3" Coexpression Atlas GSM854273_500 "Myeloid Cells, DC.103-11b+F4/80lo.Kd, CD45+ CD11c+ I-A/I-E+ CD11b+ F4/80lo, Kidney, avg-3" "Immgen.org, GSE15907" 4.03E-04 1.00E+00 1.89E-03 1.72E-02 93 406 "FMNL2,RNF150,PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,ATP6V0A1,ST3GAL5,C1QC,CD86,CHN2,B4GALT6,ARHGAP22,LY86,GDA,CSF1R,CSF2RA,CSF3R,CST3,SDC3,CTNND1,CTNND2,CX3CR1,CYBB,DOCK4,MYADM,DGKG,DAPK1,SIRPA,SRGAP3,EBI3,PLXNC1,RASA4,EPS8,IGSF6,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,FGFR1,FGR,GATM,GCNT2,HPGDS,GSN,IFI16,LRRC25,DOCK7,IL6R,DIPK1A,ITGAM,L1CAM,LIFR,LMO2,VWA5A,GPR155,MEF2C,AFDN,MYO5A,RTL5,NCF2,CLEC9A,P2RX7,PFKFB4,CDK14,PLTP,PILRA,PTAFR,RAB3IL1,PID1,C1orf54,PRR5L,ACER3,LRRK2,RTN1,DGLUCY,CCDC88A,SLC11A1,TRERF1,SULF2,KIAA0930,TF,TIAM1,TLR4,TRPS1,LAT2,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.14E-04 1.00E+00 1.94E-03 1.77E-02 15 37 "PCDH10,DCLK1,EPHA5,TMEM132C,FOXF2,MEGF10,DNER,WIF1,IFI16,MYH3,PRRX1,ZFHX4,SALL1,CSRNP3,TAC1" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K3 facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K3 Gudmap RNAseq 4.19E-04 1.00E+00 1.96E-03 1.79E-02 60 240 "ACHE,C1QTNF1,PDE8B,MYOM1,ARHGEF6,CP,DGKB,ZNF804A,LRRC17,EPHB1,TLR7,RASL12,ST3GAL6,CHST15,FCGRT,TPPP3,HIGD1B,LOXL3,STON1,NR3C1,GRM7,GUCY1A1,GUCY1B1,IL6R,IL6ST,IL11RA,KCND3,TTYH2,CCDC80,LAYN,P2RX7,PDE1A,PDE3A,PDGFRA,ABCB1,SERPINE2,PLCL1,PLEC,FXYD1,PPARA,PTN,ZMAT4,SGK1,DOCK10,LIMS2,SLC8A1,ZCCHC24,NKAIN2,PDLIM2,TNS2,ENHO,TLR4,DAAM2,TNS1,TMEFF2,ZBTB38,PLSCR4,FAM13C,MSRB3,SSPN" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_1000_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.26E-04 1.00E+00 1.99E-03 1.81E-02 30 99 "CASK,RNF182,RUNX1T1,CLIP3,ZEB2,GSDME,ALKBH8,EDNRB,PRMT5,MEX3B,STMN2,LIFR,NCAM1,LRRN3,ROBO2,CSRNP3,SFPQ,WDR37,ZKSCAN3,RBM26,RGL1,SULF2,KLHL4,CUX2,CLASP1,ASXL3,TPM1,TRIO,WNT7A,ST8SIA2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.34E-04 1.00E+00 2.02E-03 1.84E-02 54 211 "SNX32,ADGRF5,SPARCL1,SEMA6A,MTMR2,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,CTNND1,MYEF2,EDIL3,EDNRB,KLHL5,SORBS3,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,NPDC1,TUBA1A" Coexpression Atlas GSM538260_500 "Myeloid Cells, DC.8+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2" "Immgen.org, GSE15907" 4.34E-04 1.00E+00 2.02E-03 1.84E-02 94 412 "CPNE2,FMNL2,ADORA3,RNF150,ADRB2,ADGRF5,ALCAM,FGD2,SHTN1,CASK,TMEFF1,ARHGAP5,N4BP2L1,ADAM23,ST3GAL5,CACNA1E,SPAG9,CD86,SCARB1,CD38,CD81,SRSF11,ZFYVE9,LY86,FAM149A,SLC4A7,SLC4A8,CSF2RA,CST3,SDC3,CTNND1,CYBB,HDAC9,DBN1,SRGAP3,CDON,ARRDC4,PLXNC1,PLEKHO1,EPS8,IGSF6,FCGRT,OLFM1,FLT1,TMEM107,GALC,NEK6,GATM,RAB30,MAP4K5,HPS5,IRF8,LRRC25,DOCK7,JAK2,KIT,ASPRV1,ADAM22,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,PFKFB3,CDK14,PRKAB2,RASGEF1B,RAB39A,SLC22A23,PTAFR,MARCH1,PID1,C1orf54,ROGDI,SNX22,PRR5L,ACER3,LRRK2,RTN1,MRAS,SLC8A1,CCDC88A,SLC11A1,SLC12A2,FNBP1,SULF2,SEPT3,ADGRL3,CYB561A3,DDHD1,TRPM2,CADM1,PLD4,PIANP" Coexpression Atlas GSM399442_100 "Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2" "Immgen.org, GSE15907" 4.35E-04 1.00E+00 2.03E-03 1.85E-02 27 86 "CPNE2,ADGRG1,FADS2,GDA,CSF3R,CTNND1,ARHGAP32,PLXNC1,MED12L,GCNT2,TUBA8,GRB10,GUCY1A1,HLF,ICA1,DOCK7,KIT,LMO2,MEIS1,MYCN,OCRL,PBX1,ITSN1,SLC14A1,TEK,TIE1,STXBP4" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k5 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.35E-04 1.00E+00 2.03E-03 1.85E-02 27 86 "EMILIN3,CACNA2D1,CHN2,CNTN1,COL9A1,NCALD,MRVI1,DACH2,PNMA2,DKK3,MEGF10,GFRA2,RAB40B,NEGR1,KCND3,CLDN11,PENK,PTX3,TTLL7,LGI2,SH3BGR,PLCB1,ANO4,VWC2,HHIP,SYNPO2,FLRT2" Coexpression Atlas gudmap_developingGonad_P2_testes_500_k2 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.36E-04 1.00E+00 2.03E-03 1.85E-02 34 117 "TTYH1,TMCC3,ADCYAP1R1,ADORA1,NR0B1,C1QTNF3,LTBP4,MMD2,VXN,ADGRG1,JAM2,ARHGEF4,TOX,SPOCK2,PLPPR4,EBF1,PLXNC1,ELN,LRRC17,RASL12,REEP2,GATM,HSD17B1,IL6ST,NRBP2,MYO7A,NFIX,SEMA5B,PTPRE,SOX8,SH3GL2,SLC1A6,EFHD1,HHIP" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal A_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal A_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.37E-04 1.00E+00 2.03E-03 1.85E-02 67 275 "NDRG2,AGT,SPARCL1,LTBP4,OGT,TMEM263,CACNB2,RUNX1T1,CD81,CDO1,CFL2,SLIT2,CNN3,MAGED1,CP,AKAP12,SNCAIP,VCAN,DOCK4,ZEB2,GOLT1B,EDNRA,EDNRB,TMTC1,PCOLCE2,LRRC17,NCALD,ETV1,FHL1,ERGIC3,DKK3,FREM1,SPIN1,FERMT2,GPM6B,GRB10,NR3C1,GSN,GUCY1A1,GYG1,GPR45,IGF1,KCNK3,TTYH2,NNAT,PBX1,PCSK5,PDGFRA,ENPP2,PENK,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,DAAM2,SSBP2,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal A_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal A_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.37E-04 1.00E+00 2.03E-03 1.85E-02 67 275 "NDRG2,AGT,SPARCL1,LTBP4,OGT,TMEM263,CACNB2,RUNX1T1,CD81,CDO1,CFL2,SLIT2,CNN3,MAGED1,CP,AKAP12,SNCAIP,VCAN,DOCK4,ZEB2,GOLT1B,EDNRA,EDNRB,TMTC1,PCOLCE2,LRRC17,NCALD,ETV1,FHL1,ERGIC3,DKK3,FREM1,SPIN1,FERMT2,GPM6B,GRB10,NR3C1,GSN,GUCY1A1,GYG1,GPR45,IGF1,KCNK3,TTYH2,NNAT,PBX1,PCSK5,PDGFRA,ENPP2,PENK,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,DAAM2,SSBP2,TUBA1A" Coexpression Atlas GSM605872_100 "Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 4.38E-04 1.00E+00 2.03E-03 1.85E-02 23 69 "ABCD2,APP,ZFYVE9,LY86,GDA,CSF1R,CSF3R,VCAN,CYBB,SIRPA,IGSF6,TLR7,SIRPB1,FCGR1A,HP,IFI16,ITGAM,MSR1,PILRA,PID1,FGD4,TPD52,PLD4" Coexpression Atlas GSM605856_500 "Myeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 4.46E-04 1.00E+00 2.06E-03 1.88E-02 98 433 "ALCAM,BCAR3,ABCD2,GAS7,APOC2,APP,SHTN1,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,C1QC,CD38,MS4A7,B4GALT6,TPP1,LY86,GDA,CSF1R,CSF3R,CST3,SDC3,CTNND1,CYBB,MYADM,KIAA0513,DBI,SIRPA,ZEB2,FAM78B,EDNRB,PLXNC1,EPB41L1,EPS8,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FGFR1,PCYOX1,FOLR2,AK8,TPPP3,GALC,GATM,HPGDS,GLUL,KIF3A,ATG4C,IRAK3,HNMT,IGF1,LRRC25,DOCK7,ITGAM,LAMP2,LIFR,LDLRAD3,MITF,MSR1,NCF2,OPHN1,P2RX7,P2RY1,TREM2,CDK14,PLTP,PMP22,LRP12,PILRA,DRAM2,RASGEF1B,GDPD1,PTAFR,RAB3IL1,PID1,C1orf54,ACER3,ITSN1,SLC11A1,SPP1,RGL1,SULF2,FGD4,SLC37A2,KIAA0930,TPCN2,TF,TLR4,TNS1,TPD52,LAT2,AGMO,PLD4,MARCH8" Coexpression Atlas GSM854291_500 "Myeloid Cells, DC.8-4-11b-.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.66E-04 1.00E+00 2.16E-03 1.97E-02 95 418 "CPNE2,FMNL2,DSCAML1,ADCY6,TMCC3,ADORA2A,SEMA7A,FGD2,APP,SHTN1,ARHGAP5,ZBTB10,N4BP2L1,ATP6V0A1,ADAM23,CD86,CDH2,UBE2L6,B4GALT6,ARHGAP22,CLU,STOML1,LY86,SLC4A8,ABCG1,CSF1,CSF1R,CST3,SDC3,CX3CR1,CYBB,MYADM,SIRPA,RABGAP1L,ARRDC4,EBI3,PLXNC1,RASA4,ENO2,MTSS1L,EXTL1,FCGRT,FGR,ZMYND15,NEK6,MTHFD2,GATM,RAB30,ADAP1,SLC2A6,GYG1,HSF2,IRF8,DOCK7,SCIN,INSM1,TUBB2B,LIFR,VWA5A,ASPRV1,ADAM11,CLEC9A,PBX1,PFKFB3,CDK14,CCSER2,SLC22A23,PID1,ROGDI,RGS12,PRR5L,LRRK2,RTN1,SEMA6D,SCN4B,ARHGEF40,CCDC88A,SAMSN1,RGL1,SULF2,STXBP1,TMEM150C,ARC,ATMIN,PHF24,CYB561A3,TF,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,ZBTB38,SPIRE1,ITM2C,PLD4" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k3_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.69E-04 1.00E+00 2.16E-03 1.97E-02 21 61 "CDC14B,NRN1,AFF2,GABRA4,TRAF3IP2,PCDH11X,KLHL23,MATN2,MEIS1,NFIA,PDE1A,PCDH18,REV3L,TMEM206,LGR4,SMOC1,ST5,ADGRL3,OBSL1,ZFPM2,TRPS1" Coexpression Atlas Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K1 FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.69E-04 1.00E+00 2.16E-03 1.97E-02 21 61 "ERMN,VAT1L,TTLL9,CA4,CBLN1,INA,CNTFR,FAM169A,GREB1,ST8SIA3,LPAR6,PIPOX,NLGN3,NKAIN4,CCDC40,FIGN,STK32B,PBLD,WASHC4,RBFOX3,ZBTB16" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_500_k1 DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.69E-04 1.00E+00 2.16E-03 1.97E-02 21 61 "TTYH1,CSMD3,SORCS1,BEND6,MMD2,CBLN1,JAM2,FOXF2,SGIP1,DNER,MAEL,HSD17B1,IFI16,RASGRF1,SOX8,ARX,EFHD1,C11orf87,HHIP,LYPD6,CBLN2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.70E-04 1.00E+00 2.17E-03 1.97E-02 78 331 "EMILIN3,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,ARHGEF6,COL9A2,ABI3BP,ANKRD44,SNCAIP,C8orf34,CCDC3,DNM1,ABCC9,ELN,EPB41L1,LRRC17,FCGRT,TRIM16,STAU2,TVP23A,ZMAT1,ZNF276,GRIK4,WIF1,SYNPO,IL11RA,CREG2,VWA5A,SRSF12,CD200,MSR1,RSPO2,TCEAL5,FXYD7,NFIX,NRGN,ZNF827,CNTN3,PDE4D,PRRX1,SDK2,EPB41L4B,CCDC144B,CNTLN,ACSS3,IQSEC3,RAP1GAP,BEND5,ZFHX4,MYH14,MRAP2,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC8A1,PDZRN3,ADAMTS17,PLCB1,UNC5D,ADGRL3,TBX15,SATB2,PHF24,PIK3R5,SYNPO2,TRPS1,TSPAN11,ZNF32,PMEPA1,NAV3,KLHDC1" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k3_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.71E-04 1.00E+00 2.17E-03 1.98E-02 124 570 "CCDC85A,ADORA2A,HECW2,ADGRF5,MAP4K3,APBB2,SHROOM2,ARRB1,DOCK11,ADAM15,NRP2,PROM1,ARHGEF7,C1QC,LDLRAD4,THSD7A,CALM1,FMNL3,SCARB1,CD38,ARHGEF2,LRRFIP1,MS4A7,TAOK2,ABCG2,TMEM184B,MAP4K4,LY86,CDC42BPB,CRMP1,HAPLN1,CSF1R,USP6NL,CX3CR1,CYBB,KIAA0513,RASSF2,GIT2,PITPNC1,ELMO1,SACS,FAM107B,ECM2,EBF1,EDNRB,SH3GLB1,LPAR6,CALCRL,PLEKHO1,RASGRP2,STX2,DENND4A,CORO2B,KIAA1109,FLT1,PDLIM5,TRIM16,FYB1,GAP43,INPP5K,PCDH17,GGTA1P,HPGDS,GLUL,LILRB4,LPAR4,RAPGEF4,STMN2,GRIA2,MAP4K5,NCKAP1L,HTR2A,ICA1,INSYN2,LMO2,TM6SF1,MEF2C,MYO6,CLEC9A,PDE2A,PDE4B,PDE4D,ABCB1,PLCL1,SPATA6,DRAM2,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,KCTD17,PRR5L,SGK1,MAGI3,PREX2,BTBD3,SLC15A2,CPEB4,LIMCH1,UNC5B,COLGALT2,SAMSN1,THSD1,PLCB1,KLHL4,TEK,TF,TIE1,HEY1,TJP1,TLR4,RFTN2,WIPF1,SLC26A10,GDPD5,NAV3,FAM13C,DOCK8,JMJD1C,MSRB3,ZDHHC20,SPATA13" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_k1_200 kidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.72E-04 1.00E+00 2.17E-03 1.98E-02 35 122 "C1QTNF1,EPB41L5,UPRT,B3GALT2,THSD7A,MYOM2,DOCK4,ARHGAP24,AIF1L,MAGI2,OPTN,TLR7,ACSL4,ST3GAL6,SGIP1,ST6GALNAC3,GABRA4,GABRB1,ILDR2,GALC,IQGAP2,MALT1,PARD3B,SYNPO,MYO6,PTH1R,PTPRO,RIPOR1,RAVER2,ROBO2,FAM81A,TMEM150C,FRYL,DAAM2,CERS6" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k2 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.78E-04 1.00E+00 2.20E-03 2.00E-02 62 251 "SERPINA3,SPARCL1,ANK1,ATP2A2,MYOM1,NRP2,CACNB4,CAMK2D,RAB3C,AKAP5,MYADM,DMPK,CPEB2,DTNA,ABCC5,SH3GLB1,ELN,PRKAG2,FHL1,FLNC,SORBS1,ILDR2,IGSF5,FERMT2,PRUNE2,TPPP,BVES,IL6ST,KCNMA1,IL17D,NPTX2,PDE4B,PDE4D,PFKP,SCHIP1,PRKCB,PTHLH,RYR3,SCN2A,STUM,SH3BGR,FHOD3,SMTN,LIMS2,RIMS1,TNIK,FNBP1,DBNDD2,NACAD,POPDC3,HHIP,ENHO,TNNT1,TNS1,RASD2,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,ZBTB16,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.80E-04 1.00E+00 2.21E-03 2.01E-02 74 311 "ABCF1,ACLY,ADAM23,BLM,ZNF599,CACNA2D1,PTBP2,CANX,SLC16A4,CDK11B,LRBA,MAGI1,C4orf33,HECTD1,NIPBL,IQCK,SLC4A7,SLC4A8,IGDCC3,NCOR1,CLIP3,PHF14,TCAF1,TOX,TBC1D5,KIAA0586,JAKMIP2,DDX46,CASP8AP2,KLHL5,NSRP1,CORO2B,ZNF605,ADGRA1,HIGD1B,C15orf41,TCERG1,CIT,KIF3A,SMAP1,KIF2A,KIF5C,HECTD2,TM6SF1,RSPO2,MYO5A,NASP,NEK1,SMIM11A,ODF2,GPR137C,FAM98B,DIRAS2,ANKHD1,STRC,FAM184A,ARID4A,RBBP6,REV3L,CLIP1,SAFB,CCDC88A,BDP1,SOX11,NEK4,SYNE2,TCF7L2,DICER1,STXBP4,ZNF23,ZNF184,GAL3ST3,HNRNPA3,NETO2" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k3_1000 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 4.89E-04 1.00E+00 2.25E-03 2.05E-02 115 523 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,BIN1,MAP4K3,APBB2,SHROOM2,ATP1B3,DOCK11,NRP2,ARHGEF7,C1QC,LDB2,FMNL3,CD38,MS4A7,ABCG2,MAP4K4,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,LRRC3B,USP6NL,CX3CR1,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,EBF1,EDN1,EDNRB,PHF20L1,LPAR6,CALCRL,RASGRP2,DENND4A,IGSF6,CORO2B,DLC1,FLT1,UFM1,PDLIM5,FYB1,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,GPM6A,LPAR4,RAPGEF4,GRIA2,MAP4K5,NCKAP1L,ELOVL5,ZDHHC15,ICA1,ITPKB,INSYN2,LIFR,LMO2,PIK3AP1,TM6SF1,MEF2C,MEST,MSR1,MYO6,OPHN1,PDE2A,PDE4B,ABCB1,PLCL1,SPATA6,MINDY2,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,SLA,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,COLGALT2,THSD1,PLCB1,KLHL4,TCF4,TEK,TF,TIE1,HEY1,TJP1,TRPC3,RFTN2,WIPF1,ZNF711,NAV3,PLD4,FAM13C,DOCK8,ZDHHC20,RNF146,SPATA13" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_500 kidney_adult_Mesangium_Meis_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.92E-04 1.00E+00 2.26E-03 2.06E-02 97 429 "CPNE2,ACHE,ADCY6,APBB2,APP,PDE8B,DDX3Y,MYOM1,NRP2,CACNA2D1,ARHGEF6,CP,CSF1,FEZ2,KIAA0040,HDAC9,DGKB,ZNF804A,ZEB2,NR1D2,ECM2,ABCC9,EBF1,EDNRA,FRY,CALCRL,RCAN2,LRRC17,RASGRP2,EPS8,CEP85L,DLC1,ST3GAL6,CHST15,TVP23A,ERAP1,RAPGEF4,NR3C1,GUCY1A2,GUCY1A1,GUCY1B1,FRMD3,HLF,IFI16,IL6ST,INPP5B,LIFR,MEF2C,CCDC80,LAYN,NCF2,NFIX,DDR2,PDE3A,PDGFRA,ABCB1,SERPINE2,SERPINI1,PIK3R1,PLCL1,FXYD1,PCDH18,SEPT4,MINDY2,PRKAB2,PKIA,SNRK,PTN,PTPRB,PYGM,ZMAT4,RGS4,RERGL,WLS,SGK1,DOCK10,PREX2,SLC8A1,SLC12A2,CPEB4,ITPRID2,RGL1,ANKRD12,ADGRL3,TMEM136,SYNE1,PSD3,TNS2,GPRIN3,TEK,TLR4,DAAM2,TNS1,TRPC1,TMEFF2,DOCK8,CPNE4" Coexpression Atlas facebase_RNAseq_e10.5_Emin_MedNas_2500_K3 facebase_RNAseq_e10.5_Emin_MedNas_2500_K3 Gudmap RNAseq 4.96E-04 1.00E+00 2.27E-03 2.07E-02 28 91 "CPNE2,ACHE,ADD2,NRXN3,QKI,CP,ZNF804A,EDNRB,MRVI1,HIGD1B,TUBA8,NTNG2,GPR12,GUCY1A2,GUCY1B1,KCNJ5,MAPT,SHC3,CLEC9A,NTRK2,ABCB1,SERPINI1,PLCB2,SLC1A3,CABCOCO1,GALNT17,TNFRSF1B,TRPC1" Coexpression Atlas GSM476672_500 "gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3" "Immgen.org, GSE15907" 4.99E-04 1.00E+00 2.28E-03 2.08E-02 90 393 "ACTN1,FMNL2,ADORA2A,PKP4,ATP1B3,C1QC,BAIAP3,CD86,CD38,DGKI,CD81,CHN2,LY86,CSF1R,IPCEF1,SDC3,CTNND1,CYBB,DOCK4,HDAC9,HDAC4,TOX,SPOCK2,SIRPA,PITPNC1,KBTBD11,DMPK,HEYL,RASGRP1,PCOLCE2,IGSF6,TLR7,FCGR1A,FCGR3A,FCGRT,FGF13,FGR,NSG2,FYN,TRAF3IP2,GATM,GFRA2,HPGDS,AGFG1,IGF1,LRRC25,JAK1,KCNA2,KCNJ10,KCNJ16,KIT,KLRC2,KLRC3,TTYH2,MYO9A,P2RY13,ZNF827,PDE2A,ABCB1,PILRA,SH3KBP1,PPP3CC,RASGEF1B,GDPD1,SIDT1,RAB3IL1,PRR5L,WLS,SEMA6D,SATB1,SELL,FAM102A,DZIP1,SLC11A1,SLC12A2,TET1,TNIK,EPB41L3,RGL1,SYT11,ADGRL3,TCF7,TCF7L2,TF,TLR4,TRIO,RUNDC3B,TRPM2,CADM1,PLD4" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_nonFloorPlate_500 e8.5_NeuroEpith_nonFloorPlate_top-relative-expression-ranked_500 FaceBase_ST1 4.99E-04 1.00E+00 2.28E-03 2.08E-02 96 424 "ERMN,PDXK,FGF17,BID,BMP7,CA4,CBLN1,INA,CIART,SOCS6,LHX2,NMT2,FAM19A5,SULT4A1,CNTFR,CNRIP1,CTH,IP6K1,JAKMIP2,FBXL5,GSDME,RAB39B,ST8SIA3,TSPAN5,EDN1,PHF20L1,LPAR6,PLEKHA1,EML1,PIPOX,REEP2,ARMCX1,CEP78,NOP56,PRELID3A,B4GALNT1,C15orf41,GATM,C1QL1,GLDC,TOX3,PCSK1N,LPAR4,PRDM5,RNF165,KAT7,FRMD5,ELOVL5,ICA1,METTL21A,KCNK1,IPO5,LMO1,PACRG,MAOB,AQP11,CHIC1,MYCN,PAX6,CYTL1,PCDH18,PMP22,PPP2R5C,PRKCZ,ELOVL2,PTPRZ1,PEX2,DPF2,RPRD1A,TMEM206,ELP2,ARMH4,ADAL,NCBP3,RMI1,MAPK12,SLC4A3,SOX2,SPATA7,LHPP,SYT11,TAC1,MTCL1,ROBO3,WSCD1,DMXL2,TIMP4,TK2,TNNT1,TPD52,TRH,SLAIN1,LMAN2L,PDSS2,ACTR3B,ZDHHC20" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells A_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells A_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 5.05E-04 1.00E+00 2.31E-03 2.10E-02 56 222 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNN3,CDC42BPB,HAPLN1,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,LPAR6,SORBS3,CALCRL,FLT1,TRIM16,PCDH17,LYVE1,STMN2,GSTM5,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RDX,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TUBB2A,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells A_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells A_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 5.05E-04 1.00E+00 2.31E-03 2.10E-02 56 222 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNN3,CDC42BPB,HAPLN1,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,LPAR6,SORBS3,CALCRL,FLT1,TRIM16,PCDH17,LYVE1,STMN2,GSTM5,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RDX,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TUBB2A,TUBA1A" Coexpression Atlas Lungmap Mouse Lung E16.5 Endothelial Subtype Mature Endothelial Lungmap Mouse Lung E16.5 Endothelial Subtype Mature Endothelial Lungmap CCHMC 5.07E-04 1.00E+00 2.31E-03 2.11E-02 95 419 "RALGAPA1,PLEKHG5,CCDC85A,ADGRF5,SPARCL1,APBB2,APOC1,SHROOM2,PRX,ARRB1,ATP1B3,ADAM15,ARHGEF7,SGCE,SPAG9,SCARB1,ARHGEF2,ADGRG1,CNOT8,JAM2,QKI,CDC42BPB,CREM,CREB5,LRRC3B,CTNND1,GIT2,ARMCX4,PITPNC1,SLC12A6,EDIL3,EDN1,KLHL5,PHF20L1,APH1A,LPAR6,PLEKHA1,ARMCX1,CORO2B,ST3GAL6,NBEA,PDLIM5,TRIM16,FYN,GAP43,INPP5K,TOX3,DCLK2,ADGRA3,GPD2,STMN2,ADAMTS13,MAP4K5,PACSIN2,AGFG1,ITPKB,MEIS2,KITLG,NELL1,CLEC9A,PDE2A,PDE4B,CDK14,PLEC,PLTP,POLG,DRAM2,GDPD1,WBP1L,SNRK,TMEM255A,FAT4,RAP1GDS1,MAPK12,BTBD3,GKAP1,SCN3B,CEP68,SYNE2,MMS19,TAL1,TCF4,SIN3B,ZEB1,DOCK9,TNS2,ARHGAP9,DICER1,HEY1,LRRC8A,SH3GLB2,SLC38A1,MPPE1,FAM13C,NHSL1" Coexpression Atlas Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 2 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 2 Lungmap CCHMC 5.15E-04 1.00E+00 2.35E-03 2.14E-02 94 414 "NDRG2,AXIN2,ADORA2A,INTS2,SRPX,USP28,SEMA4G,RUNX1T1,CDO1,CHN1,FAM189A2,MAGED1,ABI3BP,TBPL1,CNRIP1,PNKD,AKAP12,VCAN,PDE4DIP,DCAF4,BOC,ARHGAP24,DAPK1,HEPH,TIAM2,FBXO25,RCAN1,GOLT1B,EDNRA,PLXNC1,EIF4G2,PCOLCE2,EML1,STARD3NL,LRRC17,RASGRP2,MTSS1L,RABEPK,ETV1,RASL12,ARMCX1,TUBA1B,FGFR3,TRAF3IP2,EML4,GSN,PTPN5,GSTM5,IDH3A,IDH3B,INPP5B,NCOA7,MAPT,MATN2,MEF2C,MOV10,MYO6,NRCAM,PBX1,SERPINE2,ZFYVE21,LRP12,POLG,PPP2R5C,BCAS3,PXK,PYGM,FAT4,ZCWPW1,ARID4A,DPF2,RGS10,ROBO1,ROBO2,ELP2,RYR3,ATXN7,PUF60,ABLIM3,RUFY2,FAM214B,RAB3GAP1,TET1,PDZD2,PDLIM2,PSD3,PCDHA1,CHST8,ANKRD24,FRRS1L,NSD2,ANKS1B,ADAMTS9,CAMK1G" Coexpression Atlas heart muscle heart muscle Human Protein Atlas 5.24E-04 1.00E+00 2.39E-03 2.18E-02 51 198 "ACTN2,ADCY5,HHATL,MYH7B,PPFIA4,ATP1A3,MYOM1,DIRAS1,MYOM2,CDH2,LSMEM2,AKAP6,CRYM,PLCXD3,CFAP61,EEF1A2,SRPK3,DUSP27,FGF12,KBTBD12,DKK3,C15orf41,MYOZ2,TUBA8,GPR22,PLPP7,GRM1,FRMD5,FRMD3,KCNJ4,CTNNA3,MYH6,MYH7,MYL3,NPPA,PDE1C,PGAM2,SCHIP1,FITM2,KCNIP2,SCN2B,SH3BGR,FHOD3,SLC4A3,SLC8A1,SPHKAP,POPDC3,VWC2,THBS4,NDRG4,ST8SIA2" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000 FaceBase_RNAseq 5.31E-04 1.00E+00 2.41E-03 2.20E-02 199 977 "EMILIN3,SYS1,ACTN2,KDM5D,NDRG2,GALNT16,ADCY2,CCDC85A,WDR35,C1QTNF1,ALAD,ARHGAP20,LTBP4,GPRASP2,CDC42BPA,SMIM29,PHYHD1,CDK10,ASTN1,DDX3Y,CCDC181,ADGRB2,BCS1L,C1QC,CACNA1G,LDLRAD4,CACNA1B,DDR1,CACNA2D1,DIRAS1,CAMK2G,ARHGEF25,FMNL3,REPS2,LONRF2,KCNAB3,CDO1,CRLF1,FOXN3,KIAA1549L,NRXN1,SLC35F1,CREB5,ANKRD44,CSF1R,FEZ1,VCAN,RUBCN,TOX,SPOCK2,RUSC2,FBXO25,RHOBTB1,CCDC3,DLG2,DMD,USP3,SHANK1,SNX29,SEMA3D,EFNA3,SUGP2,EGFR,RASA4,TNK2,ELN,TMEM35A,LRRC17,EPHA5,RACK1,CHST15,FCGRT,TESK2,FGF11,FGF12,CAP2,FOXF2,VTI1B,SEMA4D,FLYWCH1,DPYSL4,ZCCHC17,TRIM16,TPPP3,TMEM151A,NRG3,FYB1,JPH4,TMEM8B,STARD10,GFRA2,PCDH17,PPARGC1A,DHRS4,ZNF276,PCDH11X,KCNMB4,NR3C1,GSN,CLASRP,MFSD2A,WIF1,RASSF8,ACOT7,SYNPO,LRRC75A,CELF5,IL11RA,DIPK1A,ITPKB,VWA5A,SRSF12,MGAT3,CD200,CCDC80,PTOV1,NEXMIF,TCEAL5,NCAM2,NDUFA5,NELL2,NFIA,NFIX,CNTN3,PCDH9,PDE1A,PENK,NLGN3,ZFYVE21,TMEM38A,PLCL1,NECAB2,MAGEL2,NXPH1,POU6F1,NKAIN4,PRKAR1B,SLC26A11,PRODH,MDGA2,PTH1R,PTPRZ1,ZCWPW1,ZMAT4,RGS10,PBRM1,MYH14,ARMC5,EMID1,RPS20,MEG3,DGLUCY,ATXN1,LRRTM4,FOXRED1,SH3GL3,FERMT1,DOCK10,NTNG1,FHOD3,NLGN1,SLC1A2,YPEL4,CDK5RAP3,SLC12A4,SMARCD3,NPAS3,CLSTN2,ZFR2,ANKRD12,SEMA4A,MCF2L,ADGRL3,KIAA1107,MGRN1,PHF24,FAM189A1,PSD3,HHIP,TMEM9,BEX4,ANKRD24,SYNPO2,TRPC3,KCNE5,TUBB2A,FLRT1,MTCH1,CCDC136,TSPAN11,RBFOX3,NPDC1,FMN2,NDRG4,PMEPA1,CADM2,PCDH15,NAV3,SENP7" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k1 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.37E-04 1.00E+00 2.44E-03 2.22E-02 71 297 "KLHL32,ALCAM,SEMA7A,EPB41L5,ST3GAL5,OSGIN2,THSD7A,KALRN,HIP1R,LRRFIP1,CACNA2D2,RNF14,RIPOR2,ARHGAP24,AIF1L,MAGI2,ALKBH8,NTM,TMCC2,KBTBD11,CD99L2,DNM2,OPTN,SRPK3,RASGRP2,CDHR1,CORO2B,ST3GAL6,TESK2,SGIP1,CGREF1,GABRA4,ILDR2,IQGAP2,SRRM4,IGSF5,GGT5,PARD3B,GRM7,SYNPO,HP,ZNF385B,MAPT,SYT9,LYRM9,PDE4B,SERPINI1,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,RAB3IL1,FAM184A,DUSP15,ROBO2,SCN7A,FAM19A1,GALNT10,ANKRD6,RUFY2,SNCA,DDN,STX1A,TMEM150C,PDLIM2,ARHGAP9,DAAM2,ZNF23,TMEM178A,RNF170" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.56E-04 1.00E+00 2.53E-03 2.30E-02 35 123 "OSBPL6,OSBPL8,ALDH7A1,DST,WASF1,CA8,CACNA2D1,NMT2,RABGAP1L,FHL1,SYNCRIP,PDLIM5,GALC,RAPGEF6,ATE1,ZHX1,ZDHHC15,LIMS1,NCOA7,CHIC1,PDE1C,PFKP,MINDY2,RYR3,FAM126B,ZHX3,NPAS3,ARHGEF9,VPS13A,COBL,WASHC4,ZFP91,ERCC6L2,TRPS1,VLDLR" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.57E-04 1.00E+00 2.53E-03 2.30E-02 29 96 "ASPHD1,CHGA,CLIP3,KBTBD11,SLC29A4,ATL1,BSCL2,TUBB4A,CORO2B,PCSK1N,GNG3,GPR17,CELF3,SCRG1,KCNN2,PACRG,PCBP3,SLC10A4,CYTL1,PPP1R1A,PRPH,CRTAC1,RIT2,SST,GSE1,SYN1,SSBP2,TMEFF2,NPDC1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k4 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.67E-04 1.00E+00 2.57E-03 2.34E-02 31 105 "PCDH19,SYT13,CASK,USP2,CHGB,EBF1,ATL1,CAMSAP1,TMEM107,GAA,NEK6,GPT2,ATXN2L,MAOB,MDFI,MEIS2,MYH3,FXYD7,NNAT,PCSK5,GPR85,PLTP,ING3,MED1,PTPRD,TMEM255A,MEG3,MTERF2,SLN,TRIO,PMEPA1" Coexpression Atlas GSM605802_500 "gamma delta T cells, Tgd.vg5+.act.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44hi, Small Intestine, avg-3" "Immgen.org, GSE15907" 5.68E-04 1.00E+00 2.57E-03 2.35E-02 93 410 "GRAMD1B,MTA3,APLP1,BAIAP3,CAPN3,HIP1R,CD38,ADGRG1,RCBTB2,CHN2,FADS2,OSBPL3,IPCEF1,PPP1R16B,GPRASP1,TOX,SPOCK2,PITPNC1,DNAJC6,SRGAP3,RABGAP1L,DPYSL2,ARRDC4,HEYL,RASGRP1,DENND4A,ST3GAL6,FDFT1,FGR,HVCN1,ST6GALNAC3,FYN,IGSF5,GCNT2,HPGDS,GPD2,B4GALNT4,GPR34,PADI2,ACOT7,HMGCR,ZDHHC15,CFAP126,AGFG1,SCIN,INPP5B,KCNK1,KIT,STXBP5,HECTD2,LSS,MAP2,SESN3,STK32C,MYO6,P2RX7,ZNF827,PDE3B,PFKP,ABCB1,PLTP,SEPT4,PPP2R2C,PPP2R5C,PPP3CC,PRKACB,SYTL2,SIDT1,SUSD4,ZMAT4,PRR5L,WLS,ATXN1,SEC14L1,MRAS,FAM102A,CLSTN1,ELMO2,TRERF1,TNIK,SPP1,TEX2,SULF2,ACSBG1,KLHL4,TCF7,FRYL,C18orf54,TNFRSF1B,RUNDC3B,VIPR2,LAT2,PMEPA1" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_500 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.72E-04 1.00E+00 2.59E-03 2.36E-02 7 11 "LSAMP,NTRK3,PENK,SCN2A,FAM19A1,ASTN2,TNR" Coexpression Atlas gudmap_developingGonad_e11.5_testes_k5_100 DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.72E-04 1.00E+00 2.59E-03 2.36E-02 7 11 "TUBB3,TUBB2B,NEFM,SOX2,ZIC1,PCBP4,VANGL2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 5.93E-04 1.00E+00 2.68E-03 2.44E-02 61 248 "ZNF608,ADGRF5,SPARCL1,SEMA6A,PKP4,DGKZ,MTMR2,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,CTNND1,GIT2,EDIL3,EDNRB,KLHL5,SORBS3,CALCRL,HSPA12B,FAM198B,FLT1,NCKAP1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,AFDN,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,MYCBP2,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,NPDC1,TUBA1A" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000_k4 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.96E-04 1.00E+00 2.69E-03 2.45E-02 70 293 "TTYH1,EMILIN3,TMCC3,ADCYAP1R1,ADORA1,NR0B1,SORCS2,C1QTNF3,ARHGAP20,LTBP4,AMH,SEMA7A,ARHGDIG,RGS11,ST3GAL5,MMD2,CAMK2D,VXN,CBLN1,ADGRG1,JAM2,CLU,ARHGEF4,SPOCK2,PLPPR4,RCAN1,DTNA,EBF1,EDNRA,MBNL2,PLXNC1,ELN,LRRC17,RASL12,FYN,GATM,CSDC2,GPM6B,GPR37,HSD17B1,IL6ST,JAK1,LAMA2,MEF2C,NRBP2,MT3,MYO7A,NFIA,NFIX,PAK3,PDGFRA,SEMA5B,PLEC,FXYD1,PTPRE,TMEM206,MEG3,SH3GL2,SLC1A6,EFHD1,SPP1,ACSBG1,TBL1X,SIN3B,HHIP,NR2C2,TST,SGK3,UBTF,WNK1" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_200 DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.98E-04 1.00E+00 2.70E-03 2.46E-02 42 156 "LCORL,INSYN2B,BACH1,CALB1,RUNX1T1,CDH10,CHM,SLIT2,RBM39,PUM1,DOCK4,FGFR1OP2,TCAF1,EDNRA,EIF4G1,EMX2,MEX3B,SMC2,GABRA4,LPAR4,GPR37,MAEL,INSM1,KCND2,CHIC1,MEIS2,KITLG,NASP,TMEM255A,TMLHE,ROBO2,MEG3,ARX,SCMH1,SOX2,RBM26,KLHL4,CBX5,ACTR6,SSBP2,ZIC3,ADAMTS9" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_500 DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.02E-04 1.00E+00 2.71E-03 2.47E-02 89 390 "RALGAPA1,OSBPL6,TAOK1,OGT,APC,EPB41L5,AQP4,PDE8B,SLC4A4,GPR146,BMPR1B,CALB1,CANX,RGN,LRBA,CFL2,B4GALT6,CLCN3,FAM149A,COL4A5,SLC35F1,OSBPL3,IPCEF1,CTH,MFAP3L,PLPPR4,SEMA3D,TENM1,EMX2,EFEMP1,MED12L,KIAA1109,SUCO,SYNCRIP,PDLIM5,CAMKK2,GALC,RAPGEF6,SYT17,IGSF5,GFRA1,PPARGC1A,GJB1,CNDP1,PADI2,SCIN,SLC35G1,KCNC2,KCNJ10,KCNJ16,KCNK1,KIF2A,L1CAM,AQP11,CHIC1,KITLG,VWA2,PIK3C2A,KANSL1,MAPK4,RASGRF2,VEPH1,RET,REV3L,PRR5L,SCN8A,LINC00461,SOX6,TRA2B,HKDC1,SLC8A1,SCMH1,FAM126B,MYCBP2,ATP10B,FGD4,VPS13A,CAMSAP2,WASHC4,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,RPRM,UGT8,VLDLR,EMX2OS,LYPD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.03E-04 1.00E+00 2.71E-03 2.47E-02 28 92 "SERPINA3,ADGRF5,ADAM23,BCHE,NRP2,RAB3C,CHRDL1,ABCC9,PCOLCE2,EFEMP1,CAP2,PHYHIPL,DNER,GCNT2,KCNA1,IL17D,PDE4B,PDE4D,PTHLH,PTPRZ1,TTLL7,RYR3,SLC14A1,SYN2,HHIP,SYNPO2,AGMO,FAM13C" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_100 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.12E-04 1.00E+00 2.75E-03 2.51E-02 25 79 "LCORL,BACH1,RUNX1T1,CDH10,CHM,RBM39,ST18,MEX3B,LPAR4,INSM1,CHIC1,MEIS2,NASP,NEFM,PCDH8,GPR85,TMLHE,MEG3,CSRNP3,SOX2,KLHL4,CBX5,SSBP2,ZIC3,ADAMTS9" Coexpression Atlas facebase_RNAseq_e9.5_OlfPlac_2500_K0 facebase_RNAseq_e9.5_OlfPlac_2500_K0 Gudmap RNAseq 6.13E-04 1.00E+00 2.76E-03 2.51E-02 16 42 "CPNE2,NOL4,JAM2,NRXN3,IGDCC3,ELAVL4,ERBB4,ADGRV1,GRIK2,CELF3,MAP2,MAPK4,SCG5,CXXC4,ZBTB16,AP3B2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.18E-04 1.00E+00 2.77E-03 2.53E-02 30 101 "LRRC4C,TMEM108,SLC4A4,MYRF,CALB1,CNTFR,AKAP5,CLIP3,ATRNL1,BOC,DNM1,FLNC,TCEAL6,NKD1,KCND2,MAP2,MATN2,MEIS1,NFIA,NME4,PIK3R1,PLP1,PCDH18,PRRX1,PTN,MEG3,KCNIP1,PKNOX2,PALLD,ZFPM2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_500_k4 DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.32E-04 1.00E+00 2.83E-03 2.58E-02 19 54 "USP31,DPP10,CACNA1B,HAPLN1,BRINP1,GRIN3A,EDIL3,FGF13,DACH2,GABRA1,SYT17,GFRA1,PPARGC1A,SAMD5,MAGEL2,SLC15A2,SOX2,SLAIN1,SOCS4" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_500 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.34E-04 1.00E+00 2.84E-03 2.59E-02 40 147 "KLHL13,NR0B1,CACHD1,PPP4R4,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,AFF2,ZMAT1,GABRA4,PCDH11X,KLHL23,KITLG,SESN3,MTR,NFIA,PDE1A,CDK14,SERPINI1,RNASEL,ZFHX4,TMEM206,LGR4,HUNK,SLC4A3,KDM3A,UHRF1BP1L,SMOC1,ADGRL3,ACTR6,DAAM2,TNNT1,PCDH20,LYPD6,WNK3,DPF3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 6.39E-04 1.00E+00 2.86E-03 2.61E-02 56 224 "NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,DTNA,EDNRA,PCOLCE2,LRRC17,ETV1,RASL12,FGFR3,FHL1,UBE2E3,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,MAPK7,PTCH1,SEC61A2,ROBO2,TNFRSF19,ABLIM3,PREX2,LIMCH1,PALLD,ADAMTS17,TACC1,PDLIM2,TGFBR3,HHIP,VLDLR" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_200 kidney_P3_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 6.43E-04 1.00E+00 2.88E-03 2.62E-02 44 166 "ALCAM,AMPH,VAT1L,ADAM23,CACNA1G,CACNA2D1,CRYM,SNCAIP,TENM4,VCAN,SPOCK2,GSDME,SNAP91,EYA1,ST3GAL6,FGFR1,SCARA3,IGSF5,GFRA1,TDRKH,CECR2,FAM107A,HAS2,TM6SF1,NCAM1,NPY,CNTN3,PENK,FAT3,MDGA2,RAVER2,ROBO1,TMEM100,GLDN,SALL1,CNKSR2,SLC15A2,TACR1,CUX2,HEY1,HEY2,CADM1,LAMP5,SLC38A1" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype MatrixFB-A Lungmap Mouse Lung PND3 MatrixFB Subtype MatrixFB-A Lungmap CCHMC 6.62E-04 1.00E+00 2.96E-03 2.70E-02 61 249 "ADRA1B,ALCAM,SMIM29,PPP4R4,DYNLL1,ATP1A2,CACNA1D,CBR1,CD81,CDO1,CNN3,MAGED1,CP,AKAP12,VCAN,DAPK1,BRINP1,ZEB2,MBNL2,PCOLCE2,TUBA1B,DLC1,FGFR3,FHL1,DKK3,ZMYND11,GFRA2,FREM1,FERMT2,EML4,TUBA1C,GSN,GYG1,IRF8,KITLG,NAP1L1,NELL2,NFIA,NFIX,NRCAM,SERPINE2,FXYD1,PLTP,LRP12,SEPT4,PTPRD,ARID4A,ROBO2,ABLIM3,PREX2,LIMCH1,PALLD,TACC1,PDLIM2,TCF4,PCDHGA9,TNS1,TPM1,TPM4,VLDLR,TUBA1A" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500 gudmap_RNAseq_e11.5_Ureteric_stalks_2500 Gudmap RNAseq 6.63E-04 1.00E+00 2.96E-03 2.70E-02 363 1900 "SYN3,ABHD6,AS3MT,NCKAP5,ADCY6,AXIN2,SORCS1,PLEKHH1,ADORA2A,KIAA1211,PCDH19,NME5,KIAA1324,AK2,CEP126,BCAR3,ZNF687,DOC2A,AMPH,AMT,ANK3,FGD2,CNIH2,EPB41L5,APOC1,APP,SHTN1,CPNE5,LGR5,CDC14B,PDXK,ARHGDIG,PDE8B,ALDH4A1,ATP1A1,NOL4,RGS11,RGS9,BCL7A,PROM1,BMP7,BMPR1B,WASF1,BTRC,CA4,CA12,DDR1,CALB1,HAP1,HIP1R,MAP7,SHISA7,MTMR7,CBFA2T2,LRBA,LONRF2,LRWD1,CRLF1,ADGRG1,CBARP,CHGB,CHN2,B4GALT6,SLIT2,PPT2,KIAA1549L,MYL6B,TMEM59L,FAM189A2,QKI,CNR1,IGDCC3,ZNF385A,SH2B1,HAPLN1,CRYM,IPCEF1,PLCH2,CST3,PLXNA4,FAM169A,PLCXD3,CTH,GREB1,CTNND2,NOS1AP,HDAC9,KATNAL2,PHF19,ACY3,DAPK1,SPOCK2,MFAP3L,SNAP91,SGSM2,DLG3,TRAPPC9,CDON,DPP6,DTNA,DUSP9,EDNRB,SEMA3D,RBM12,APH1A,KCTD3,PLEKHA1,CERCAM,ELAVL4,EMX2,HSD17B14,ENO2,DMTN,KCNMB2,ERBB2,ERBB4,EFS,SPEG,RCSD1,EYA1,CD320,F3,REEP2,TUBB4A,ST3GAL6,ZSCAN30,SPSB4,FGF12,SEMA6C,EVL,SEMA4D,SYT3,C2orf88,POMT1,HVCN1,RASL10A,NRG3,PHYHIPL,GALNT15,GALC,SYT17,STARD10,IGSF5,FAXC,TUBA8,NFU1,GFER,GFRA1,GGT7,PPARGC1A,GJB1,RUNDC3A,GLDC,TOX3,KIAA1958,KDM2B,POLL,GNG3,LNX1,B4GALNT4,CECR2,PLPP7,RFFL,GRIK1,GRIK2,GRIK5,RNF165,GSTM5,GSTT2,MFSD2A,SLC2A6,FAM222A,MUM1,PADI2,FRMD5,ACOT7,SHISAL1,LIX1,IBA57,SLC6A17,TUBB2B,SLC35G1,KCNJ16,KCNK1,KCNK3,GATD1,KHK,L1CAM,STMN1,SYTL4,MAPT,LYPLAL1,MATK,AQP11,MBP,SYT9,ADAM11,KITLG,SAMD5,MSI1,TAGLN3,MYBPC1,MYCN,LYRM9,FXYD6,RCOR2,NEFM,NELL1,VWA2,NPY,NRCAM,KSR2,ZNF827,CDK18,PDE1C,PDE2A,PDE3B,PDE4A,PDE1B,FAM98B,PFKFB4,ZDHHC8,SEMA5B,RETREG1,PKM,KCTD15,PLCL1,EPN1,SLC25A23,PLXNB1,CDIP1,SEPT4,FAT3,POLR2F,FSD1,PPP1R1A,NKAIN4,PRKCZ,MAPK4,GDPD1,LAMA1,ELOVL2,SPDL1,PTPN13,EML5,PTPRG,PYGM,NKAIN1,TMEM231,FAM184A,SUSD4,ROGDI,RASGRF2,ZMAT4,RET,FIGN,RFX5,KCTD17,ARHGEF10L,NUDT11,C12orf49,ARMC5,PCMTD2,KIAA0895L,GLDN,PRR5L,RIMKLA,RPS6KA2,EMID1,PAQR6,SOX8,YJEFN3,RTN1,SALL1,HOGA1,SCN2B,SCN8A,HES6,TNFRSF19,SOX6,ZNF821,SCG5,SH3BGR,SH3BP2,FAM102A,SH3GL2,KIF16B,SHMT2,FHOD3,ST6GAL1,WDR37,PEX26,SLC8A1,SHANK2,SLIT1,ABTB1,INAVA,SCN3B,WDTC1,KIF21B,SOX11,BEX1,RAP1GAP2,NKAIN2,LRRC4,NCDN,STAC2,KANK1,FGD4,TMEM150C,SYP,SYT5,WWC1,TBCEL,WSCD1,CUX2,TCF7,AZIN2,CYB561A3,TMEM9,TK2,BEX4,TPD52,PRMT8,LRRC24,ZMYND8,DCBLD1,CA14,HSPBP1,CADM1,RPRM,UBE2H,UCHL1,SLAIN1,MTCH1,CCDC136,VLDLR,VSNL1,KLC2,ATP6V0E2,SLC26A10,SPHK2,POLR3H,DPYSL5,ANKS1B,SH3GLB2,MEIS3,INTS3,ZXDA,SHD,SLC38A1,RGMA,TMEM178A,CIAPIN1,SEMA3B,NAV2,PCBP4,WIPF2,WNK2,FZD3,DOCK8,AP3B2,SPATA13" Coexpression Atlas ratio_EB-blastocyst_vs_EB-fibro_2500_K5 ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#5 PCBC 6.67E-04 1.00E+00 2.98E-03 2.71E-02 38 138 "TTYH1,HECW2,PCDH19,SORCS2,PCDH10,LRRC4C,CDH18,DCT,FAM107B,DNAH9,EMX2,EN2,GABRA2,PTPRT,HPSE2,NNAT,C1orf54,FEZF2,BEND5,VEPH1,ZFHX4,KLHDC8A,ATAT1,SLC30A10,ARX,CXXC4,DMRTC1,NPAS3,HHIP,ASXL3,CSMD1,CELF4,DPYSL5,CA10,STMN4,PCDH15,SLC17A6,PAK5" Coexpression Atlas GSM605850_500 "Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 6.71E-04 1.00E+00 2.99E-03 2.73E-02 98 438 "MTUS1,ALCAM,ABCD2,APOC2,APP,SHTN1,CDC14B,CASK,ASPA,ATP1A3,ADAM15,ST3GAL5,C1QC,CD86,CD38,B4GALT6,JAM2,ZFYVE9,LY86,CP,GDA,CSF1R,CSF3R,CST3,SDC3,CTNND1,CYBB,HDAC9,MYADM,KIAA0513,DAPK1,DBI,SIRPA,ZEB2,FAM78B,EDNRB,SORBS3,EPS8,IGSF6,ETV1,TLR7,F5,FAM198B,FABP7,FCGR1A,FCGR3A,FCGRT,FER,FGFR1,PCYOX1,AK8,GLUL,ADAP1,ATG4C,IRAK3,VSIG4,HNMT,HP,IGF1,LRRC25,DOCK7,ITGAM,KCNN3,KHK,LAMP2,LIFR,ARHGAP12,LYPLAL1,MSR1,NCF2,NFIA,NUCB2,PDE2A,SNX10,PLTP,PMP22,PILRA,DRAM2,PTAFR,PID1,C1orf54,ACER3,LRRK2,ITSN1,SLC11A1,FGD4,PLCB1,ARHGEF12,TF,SLC44A1,TLR4,TRPS1,AGMO,ZBTB16,EVI5,PLD4,PLSCR4,NLRP3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.72E-04 1.00E+00 2.99E-03 2.73E-02 29 97 "ARHGAP20,CACHD1,IGDCC4,CALB1,HP1BP3,CDON,IP6K2,TRAF3IP2,RAB30,GUCY1A2,KCND2,MAP2,MATN2,MEIS1,CCDC80,NFIA,PDE1A,PIK3R1,PCDH18,LRRN3,REV3L,LGR4,HUNK,FAIM2,PEG10,ADGRL3,ZFPM2,TRPS1,PLEKHH2" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_100_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.78E-04 1.00E+00 3.02E-03 2.75E-02 13 31 "CACNB4,RBM39,CRYM,DYNC1I1,ELAVL4,EYA1,FGF1,FAM19A2,FAM107A,FRMD3,NELL1,NXPH1,SLC1A3" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K1 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 6.88E-04 1.00E+00 3.06E-03 2.79E-02 42 157 "TTLL9,ZNF599,CA4,CBLN1,FAM19A5,CHRDL1,ST8SIA3,LPAR6,PLEKHA1,PIPOX,TUBB4A,NOP56,LPAR4,CECR2,HSP90AA1,NKD1,CDH20,IPO5,AQP11,PRTG,PKM,PLTP,MAGEL2,IRX1,GDPD2,PTPN13,RPL15,SALL1,TNFRSF19,NUBPL,PKNOX2,SNRPN,NMNAT2,BEX1,PBLD,AJAP1,MTCL1,WASHC4,BEX4,ZIC2,ZBTB16,NAV2" Coexpression Atlas Arv_SC-LF_500 AravindRamakr_StemCell-LF_top-relative-expression-ranked_500 PCBC 6.90E-04 1.00E+00 3.07E-03 2.79E-02 109 496 "ADCY2,NLGN4X,PDZD4,PLA2G4C,RASL11B,KIF1A,SYT6,MAP7,CLDN10,CHGA,RAB3C,IGLON5,CABP1,COL9A1,GAL3ST1,TCEAL2,HS3ST5,RIMS4,CNTNAP2,SEC14L5,RIMS3,BRINP1,FAM57B,DPP6,EDNRB,LINC00599,SEZ6,PIPOX,ADGRV1,FABP7,PPP1R1B,C1orf61,SYT3,CSPG5,B3GAT1,MEGF10,GABRA3,GABRA5,GABRB3,SALL3,ATP8A2,PCDH11X,GPM6A,GPM6B,LPAR4,GRIA4,WIF1,IGSF21,C1orf94,NXPH2,HRH3,IGFBPL1,SHISA6,CELF5,BTBD17,IGSF1,KCND2,KCNQ2,KIF5C,CAMK2N2,FGFBP3,MATK,CPNE9,SCG3,DDX25,TCEAL5,FXYD7,NELL2,NNAT,NODAL,NPTX1,ZDHHC22,PAH,GDAP1L1,CAMKV,A2ML1,JAKMIP1,POU3F4,PPP2R2B,RAB39A,GDPD2,TMEM145,NKAIN1,SLC1A6,TMEM132D,SNCB,SOX3,SOX15,LHFPL4,ACSBG1,ZFR2,ARC,COBL,SYT4,TAC1,TAC3,TMEM151B,CHST8,ENHO,ANKRD24,VSNL1,RBFOX3,KCNK12,ZIC3,KCNT2,SLC30A3,CADM2,GAL3ST3,JPH3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_500 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 6.91E-04 1.00E+00 3.07E-03 2.79E-02 23 71 "HECW2,APOC1,DST,ST3GAL5,ADGRG1,PLXNC1,AFF2,CAMKK2,GPR37,SHISA6,LRRTM3,KCNH1,NCOA7,CTNNA3,TMEM206,RPS6KA2,MRAS,SMOC1,OBSL1,TST,ADAMTS9,NAV2,WNK3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells B_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 6.93E-04 1.00E+00 3.07E-03 2.80E-02 53 210 "CCDC85A,ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,JAM2,ABCG2,CNN3,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,LPAR6,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,RPS6KA2,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBB2A,TUBA1A" Coexpression Atlas skeletal muscle skeletal muscle Human Protein Atlas 7.03E-04 1.00E+00 3.12E-03 2.84E-02 75 320 "ACHE,ACTN2,ADCY2,HHATL,CARNS1,KCNT1,BIN1,ANK1,MYH7B,ATP1A2,MYOM1,CACNG1,CAPN3,USP6,P2RX6,NEURL1,MYOM2,IGFN1,LSMEM2,HS3ST5,LRRC3B,EEF1A2,SRPK3,DUSP27,CAP2,SEMA6C,FLNC,KBTBD12,ABLIM2,FAM184B,IP6K3,TUBA8,MSTN,GPD1,PLCD4,PLPP7,PADI2,SYNPO,MYLK2,KCNJ11,TMEM110-MUSTN1,LMO1,IL17D,MN1,MYBPC1,MYH7,MYL3,NOS1,BEST3,PGAM2,DUSP26,PHKG1,TMEM38A,PPP1R1A,PKIA,NDUFS7,PYGM,NKAIN1,MAP6D1,RXRG,RYR1,MAPK12,SH3BGR,SLC8A3,SLN,CAND2,SPTB,DDN,POPDC3,TBX15,TNNT1,TPM2,TPM3,FNDC5,HRASLS" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_1000 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.22E-04 1.00E+00 3.20E-03 2.91E-02 114 523 "CCDC85A,ADORA2A,HECW2,ADGRF5,MAP4K3,APAF1,APBB2,SHROOM2,ARRB1,ATP1B3,ADAM15,NRP2,PROM1,ARHGEF7,C1QC,THSD7A,FMNL3,CD38,LRRFIP1,ABCG2,TMEM184B,MAP4K4,LY86,CDC42BPB,CRMP1,HAPLN1,CSF1R,USP6NL,CX3CR1,CYBB,RASSF2,GIT2,PITPNC1,ELMO1,SACS,FAM107B,EBF1,EDNRB,SH3GLB1,CALCRL,RASGRP2,DENND4A,CORO2B,DLC1,KIAA1109,FLT1,UFM1,PDLIM5,TRIM16,FYB1,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,RAPGEF4,STMN2,GRIA2,MAP4K5,NCKAP1L,ICA1,INSYN2,LMO2,TM6SF1,MEF2C,MID1,CLEC9A,PDE2A,PDE4B,PDE4D,ABCB1,PLCL1,SPATA6,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,RGS3,PRR5L,SGK1,MYO18A,MAGI3,PREX2,BTBD3,SLC15A2,CPEB4,LIMCH1,UNC5B,SAMSN1,THSD1,PLCB1,KLHL4,FRYL,TEK,TF,C18orf54,TIE1,HEY1,TJP1,TLR4,TRPC3,RFTN2,WIPF1,GDPD5,NAV3,FAM13C,DOCK8,ST7,NHSL1,ZDHHC20,SPATA13" Coexpression Atlas Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap CCHMC 7.23E-04 1.00E+00 3.20E-03 2.91E-02 57 230 "NDRG3,NDRG2,SPARCL1,DYNLL1,ATP1A2,CD81,SEPT7,CDH2,ARHGEF6,CST3,ARHGAP32,DBI,ZEB2,EBF1,EDNRA,HEYL,RASGRP2,RASL12,FGFR1,FOXM1,SGIP1,DKK3,HIGD1B,GNAS,FERMT2,GSN,GUCY1A1,GUCY1B1,KCNK3,LIMS1,MAPT,MAT2A,MEST,CCDC80,NFIA,ENPP2,FXYD1,PCDH18,SEPT4,NKAIN4,TMEM100,PRR5L,EMID1,PEAR1,BTBD3,SLC12A2,LIMCH1,PALLD,PDZD2,TACC1,HHIP,TNS1,TPM1,CADM1,VSNL1,TUBA1A,TMEM178A" Coexpression Atlas GSM538263_500 "Myeloid Cells, DC.8-4-11b+.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2" "Immgen.org, GSE15907" 7.30E-04 1.00E+00 3.22E-03 2.94E-02 93 413 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,APP,SHTN1,CASK,CAPRIN2,ZBTB10,N4BP2L1,ATP6V0A1,MYOM1,ADAM23,CFLAR,LARGE1,UBE2L6,B4GALT6,ARHGAP22,CLU,LY86,SLC4A8,CSF1R,OSBPL3,ATRNL1,CST3,SDC3,CYBB,MYADM,RASSF2,SIRPA,RABGAP1L,DSCAM,ARRDC4,EFNA2,EBI3,PLXNC1,RASA4,ENO2,IGSF6,EXTL1,SIRPB1,FGR,ZMYND15,NEK6,RAB30,LOXL3,ADAP1,SLC2A6,GYG1,HSF2,DOCK7,JAK2,KIT,VWA5A,ASPRV1,CD200,CLEC9A,PFKFB3,CDK14,SSH1,CCSER2,SLC22A23,PTAFR,ROGDI,RGS12,LRRK2,RTN1,SEMA6D,ST8SIA1,SLC8A1,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,SULF2,TMEM150C,ARC,ATP11A,TCF7,SLC44A1,DDHD1,TNFRSF1B,TRPS1,FNDC5,ZBTB38,SPIRE1,WNK1,SIGLEC10,PLD4,CERS6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.37E-04 1.00E+00 3.25E-03 2.96E-02 44 167 "ADD3,LRCH2,RNF182,NRP2,CDH2,CRHBP,HAPLN1,BRINP1,AK5,EDIL3,EPHB1,MRVI1,FOXF2,PNMA2,DKK3,MEGF10,GABRA4,CHL1,LYVE1,GRIN2C,IFI16,KCNK2,IL17D,RSPO2,NAP1L2,NDP,DDR2,PDE1A,PRKCB,ZFHX4,DOCK10,SPHKAP,C11orf87,CLASP2,EPB41L3,NEK4,COBL,ANO4,ZFPM2,HHIP,THBS4,TPM1,SYNPO2,MSRB3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte E_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte E_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 7.38E-04 1.00E+00 3.25E-03 2.96E-02 66 275 "INTS2,SPARCL1,CDC42BPA,MAP4K3,CCNH,CD81,SEPT7,CDH2,CHN1,NRXN1,ABCG2,ARHGEF6,FAM107B,DMD,FARSB,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,SGIP1,HIGD1B,GNAS,FERMT2,GPM6B,PSIP1,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAT2A,MEST,CCDC80,NME4,PCDH18,SEPT4,NKAIN4,PTK2,C1orf54,RGS4,ELP2,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,ZBTB43,CLSTN2,PJA1,MGRN1,TRO,CADM1,CLDND1,TUBA1A,SMIM8,ADAMTSL3,FRMD6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte A_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte A_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 7.38E-04 1.00E+00 3.25E-03 2.96E-02 66 275 "INTS2,SPARCL1,CDC42BPA,MAP4K3,CCNH,CD81,SEPT7,CDH2,CHN1,NRXN1,ABCG2,ARHGEF6,FAM107B,DMD,FARSB,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,SGIP1,HIGD1B,GNAS,FERMT2,GPM6B,PSIP1,GUCY1A1,GUCY1B1,KCNK3,TTYH2,LAMA2,LIMS1,MAT2A,MEST,CCDC80,NME4,PCDH18,SEPT4,NKAIN4,PTK2,C1orf54,RGS4,ELP2,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,MYCBP2,DBNDD2,ZBTB43,CLSTN2,PJA1,MGRN1,TRO,CADM1,CLDND1,TUBA1A,SMIM8,ADAMTSL3,FRMD6" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K3 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 7.39E-04 1.00E+00 3.25E-03 2.96E-02 62 255 "SPTBN4,GPC2,LRBA,CCPG1,CLIP3,SNCAIP,FGFR1OP2,C8orf34,GSDME,FAM107B,ABCC9,CEP85L,ETV1,TMEM132C,HPCAL4,AFF2,SYT3,SMC2,STAU2,TMEM151A,HIGD1B,ZNF276,GUCY1A2,HLF,ICA1,IGF1,KNDC1,LIX1,KCNJ5,MAN2A2,CPNE9,TCEAL5,NFE2L2,NPY,CLEC9A,NRGN,ODF2,PDE4D,PRRX1,DIRAS2,CNTLN,RAP1GAP,NWD1,REV3L,MYH14,PLPPR3,DGLUCY,PREX2,DHX30,TET1,SMARCC2,BDP1,ARHGAP26,SATB2,SYNE1,PHF24,LEFTY2,AMACR,STXBP4,TRPS1,PMEPA1,CERS6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Pericyte Pericyte_Subtype_pericyte F_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 7.39E-04 1.00E+00 3.25E-03 2.96E-02 65 270 "SPARCL1,CDC42BPA,MAP4K3,DOCK11,CD81,CDH2,UBE2L6,CHN1,NRXN1,ARHGEF6,AKAP7,CNRIP1,FEZ2,FAM107B,DMD,GOLT1B,EBF1,EDNRA,HEYL,ABI2,BSCL2,EPB41L2,RASGRP2,RASL12,SGIP1,SARAF,DKK3,HIGD1B,GNAS,FERMT2,GUCY1A2,GUCY1A1,GUCY1B1,KCNK3,GATD1,TTYH2,LAMA2,LIMS1,MAPT,MEST,CCDC80,PCDH18,SEPT4,NKAIN4,C1orf54,RGS4,PRR5L,EMID1,PEAR1,BTBD3,SMTN,PDZD2,SOX5,MYCBP2,DBNDD2,CLSTN2,INKA2,PJA1,TAF9,CADM1,MICAL1,CLDND1,TUBA1A,TMEM178A,ADAMTSL3" Coexpression Atlas GSM605868_500 "Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4" "Immgen.org, GSE15907" 7.41E-04 1.00E+00 3.26E-03 2.97E-02 92 408 "MTUS1,ALCAM,ABCD2,FGD2,APOC2,APP,CASK,ATP1A3,ADAM15,BACH1,SCARB1,UBE2L6,ZFYVE9,LY86,GDA,CSF1R,CSF2RA,CSF3R,ATRNL1,VCAN,CST3,SDC3,CTNND1,CX3CR1,CYBB,DOCK4,MYADM,KIAA0513,DGKG,SIRPA,ZEB2,RASA4,PLEKHO1,EPS8,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,OLFM1,FGR,FLT1,CAMKK2,TPPP3,GCNT2,ADAP1,IRAK3,HP,IFI16,LRRC25,DOCK7,IL6R,ITGAM,LIFR,VWA5A,LDLRAD3,MSR1,NCF2,PFKFB4,CDK14,PLTP,PILRA,PTAFR,PTPRO,PID1,C1orf54,ARHGEF10L,PRR5L,ACER3,RTN1,SH3BP2,SLC8A1,CCDC88A,SLC11A1,SLC12A2,ELMO2,SNCA,ZCCHC24,RAP1GAP2,SULF2,FGD4,PLCB1,KIAA0930,TF,TIAM1,TLR4,TNFRSF1B,TPD52,TRPS1,AMZ1,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.52E-04 1.00E+00 3.30E-03 3.01E-02 14 35 "CADPS,ELAVL2,CALCRL,GFRA2,IGF1,MATN2,CLDN11,PRRX1,LGI2,SATB1,TROVE2,VWC2,ZFPM2,HHIP" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.53E-04 1.00E+00 3.30E-03 3.01E-02 25 80 "APBB1,ASCL1,ATP1A3,TTC9B,CLTB,PICK1,CNTFR,SLC35F1,CEND1,NSG1,GFRA2,C1QL1,B4GALNT4,ACOT7,TUBB2B,KLC1,TAGLN3,NELL2,NPY,PALM,GDAP1L1,SYP,UCHL1,MEIS3,MVB12B" Coexpression Atlas Lungmap Mouse Lung E16.5 Endothelial Lungmap Mouse Lung E16.5 Endothelial Lungmap CCHMC 7.59E-04 1.00E+00 3.33E-03 3.03E-02 100 450 "CCDC85A,HECW2,ADGRF5,SPARCL1,SEMA6A,DGKZ,SHROOM2,ATP1B3,ADAM15,SPAG9,LDB2,SCARB1,CD38,ARHGEF2,CNOT8,JAM2,ABCG2,MFSD4A,CDC42BPB,CREB5,CRMP1,HAPLN1,ABCG1,PPP1R16B,ARMCX4,PITPNC1,DPYSL2,EDIL3,EDN1,KLHL5,LPAR6,PLEKHA1,CALCRL,FAM198B,CORO2B,ST3GAL6,FLT1,SORBS1,TRIM16,ST6GALNAC3,FYN,GAP43,PCDH17,LYVE1,TOX3,LPAR4,STMN2,MAP4K5,AGFG1,ICA1,KIT,STMN1,LIMS1,LMO2,TM6SF1,MEF2C,MEIS2,MEST,KITLG,AFDN,CD200,LAYN,CLEC9A,PDE2A,PDE4B,MAPK3,GDPD1,SNRK,PTPRB,RIPOR1,TMEM255A,SH3TC2,RAP1GDS1,RPS6KA2,SCN7A,SGK1,MYO18A,PREX2,BTBD3,SCN3B,UNC5B,SPTAN1,THSD1,SYPL1,TAL1,KLHL4,TCF4,ZEB1,DOCK9,TNS2,ARHGAP9,TEK,TIE1,HEY1,TJP1,LRRC8A,NPDC1,SH3GLB2,GDPD5,NHSL1" Coexpression Atlas GSM399391_500 "alpha beta T cells, T.DP.Th, 4+ 8+ TCR-/lo 69-, Thymus, avg-3" "Immgen.org, GSE15907" 7.65E-04 1.00E+00 3.35E-03 3.06E-02 84 367 "FMNL2,ADCY6,RNF157,SYT13,PITPNM2,SEMA7A,DGKD,MIER1,ARNTL,ALDH7A1,BACH1,LDLRAD4,CACNA1E,PRC1,ADGRG1,RCBTB2,CNN3,WHRN,AKAP12,LRIG1,CSNK1E,PPP1R16B,TOX,DGKG,DAPK1,DNAJC6,NYAP1,ABCC5,RASGRP1,LPAR6,TNK2,USPL1,SLC43A2,IP6K2,FOXM1,NSG2,ARPP21,GPR162,DCLK2,ARHGAP19,HMGB1,NIM1K,TUBB2B,KCNH2,STMN1,LIG4,AQP11,LDLRAD3,AFF1,XRRA1,RCOR2,PDE4D,ZDHHC8,ANLN,PLCL1,SLC25A23,POU6F1,PRKCZ,RIPOR1,CEP97,ZDHHC14,SATB1,MAGI3,ST8SIA1,DZIP1,ANKRD6,TET1,SMARCA4,TNIK,SMOC1,MPRIP,GSE1,VAMP1,ANKRD28,SLC37A2,TCF7,TCF12,PRRT1,TRIO,SSBP2,NSD2,NAV2,MVB12B,NHSL1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells C_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 7.80E-04 1.00E+00 3.42E-03 3.11E-02 53 211 "ADGRF5,SPARCL1,SEMA6A,CDC42BPA,NUMB,LDB2,SCARB1,CD38,CNN3,CDC42BPB,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,CALCRL,FLT1,TRIM16,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBB2A,TUBA1A" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k2_500 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.90E-04 1.00E+00 3.45E-03 3.15E-02 27 89 "AXIN2,LRCH2,INSYN2B,CACNA1D,REPS2,MAGI2,NRN1,GABRB1,TCEAL6,KCND2,MAP2,KITLG,SESN3,MTR,PDE1A,CDK14,GDPD2,FAT4,RNASEL,SEMA6D,PRCD,TNFRSF19,STUM,KDM3A,DAAM2,TNNT1,LYPD6" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k1_500 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.90E-04 1.00E+00 3.45E-03 3.15E-02 27 89 "CALB1,CDH10,CHGB,SOCS6,HAPLN1,DOCK4,ZNF804A,ZEB2,EDIL3,EMX2,MEX3B,FAM19A2,MYBPC1,NASP,GPR85,PTX3,RFX3,ROBO2,PREX2,SPHKAP,ZKSCAN3,RGL1,KLHL4,ACTR6,ASXL3,NSD2,PCDH20" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k5_1000 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.91E-04 1.00E+00 3.45E-03 3.15E-02 42 158 "NR0B1,AMH,SEMA7A,DGKD,ARHGDIG,ST3GAL5,MMD2,DDR1,CBLN1,ADGRG1,CLU,NIPBL,COL9A2,PUM1,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,PTK2B,FYN,CSDC2,GPM6B,GPR37,MAEL,JAK1,KCNH1,TTYH2,MEF2C,MYO7A,PAK3,PDGFRA,SEMA5B,PTPRE,MEG3,ARX,SIN3B,LEFTY2,HHIP,TNS1,NR2C2,TST" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_500_k1 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.94E-04 1.00E+00 3.46E-03 3.16E-02 20 59 "COL9A1,NRSN1,PHF19,GRIN3A,NSG2,DACH2,MEGF10,KCNMB4,GP1BB,INSM1,KCNK2,MEIS1,TAGLN3,NTRK2,PTX3,SLC9A5,C11orf87,TAL1,ANO4,CUX2" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_500 kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.06E-04 1.00E+00 3.51E-03 3.20E-02 101 456 "ACADM,ACTN1,NDRG2,MTUS1,ADGRF5,SPARCL1,ASPA,SLC4A4,ALDH7A1,MYOM1,CA4,CACNA2D1,CACNB2,CALB1,CLDN10,REPS2,DCLK1,LGI1,NDST3,SLC22A6,ARHGEF6,CTH,ARHGAP24,DGKB,NTM,CCDC3,DMD,ABCC9,EBF1,EDIL3,EDNRA,EDNRB,HEYL,FRY,FAM13A,CERCAM,ELN,CALCRL,RCAN2,RASGRP2,ERBB4,ABCA8,EFEMP1,FHL1,CAP2,PDLIM5,FUT9,PHYHIPL,IQGAP2,IGSF5,PPARGC1A,GPM6A,RAPGEF4,GUCY1A2,GUCY1A1,GUCY1B1,HSPA1L,PLD5,SLC6A17,ITGAV,KCNJ16,MARK1,MEF2C,CCDC80,CTNNA3,NTRK3,PCSK2,PDE1A,PDE3A,ENPP2,PENK,PFKP,PGAM2,SERPINE2,SERPINI1,FXYD1,RELN,SYTL2,PTH1R,ZDHHC14,FIGN,RERGL,SALL1,SH3BGR,SLC4A3,FAM81A,SLC8A1,SLC12A2,LIMCH1,SPP1,PLCB1,THBS4,HEY2,TNS1,TPM2,TRPC1,TRPC3,VLDLR,KCNT2,KCNAB1,RGS7BP" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500_k4 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.06E-04 1.00E+00 3.51E-03 3.20E-02 31 107 "SERPINA3,ADCY5,ANK1,MYOM1,NRP2,DMPK,CPEB2,DTNA,ABCC9,FHL1,SORBS1,IGSF5,TPPP,IFI16,KCND3,PFKP,PRKCB,PTHLH,STUM,SH3BGR,FHOD3,SMTN,RIMS1,POPDC3,TNS1,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,MSRB3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 8.18E-04 1.00E+00 3.56E-03 3.25E-02 19 55 "ERMN,INA,LHX2,FAM169A,TUBB4A,GABRB3,SALL3,GLDC,TOX3,CECR2,NRCAM,IGSF11,PRTG,SALL1,LARP4,AJAP1,SLAIN1,ZIC2,ZBTB16" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1 gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1 Gudmap RNAseq 8.31E-04 1.00E+00 3.61E-03 3.29E-02 202 1002 "ABR,SLC25A25,AXIN2,SORCS1,AP1B1,PCDH19,AK2,DOC2A,AMPH,DGKZ,VAT1L,CPNE5,LGR5,CDC14B,TMEFF1,ARHGDIG,MARCH3,DYNLL1,ALDH4A1,BACH1,PROM1,BMP7,BMPR1B,WASF1,MYRF,CA4,ARHGEF2,CRLF1,B4GALT6,SLIT2,PPT2,KIAA1549L,MYL6B,HOMER3,CNTFR,SLC4A8,ZNF385A,CRMP1,HAPLN1,HINFP,IPCEF1,SIPA1L1,PLXNA4,FAM169A,CTH,GREB1,CFAP61,NOS1AP,CYBB,KATNAL2,PHF19,TMEM170A,AIF1L,DLG3,CASP8AP2,DPYSL2,ARRDC4,DTNA,DUSP9,E2F5,SEZ6L2,SEMA3D,RASA4,EIF1,EYA1,CD320,TUBB4A,ATP8A1,SPSB4,FGF12,ZMYND15,SEMA4D,HVCN1,UFM1,RASL10A,NRG3,NFU1,GFER,GJB1,TOX3,KDM2B,POLL,GNG3,CECR2,STMN2,GRIK1,GRIK2,CACFD1,RNF165,MFSD2A,LINGO1,FAM107A,CELF3,MUM1,HAS2,PADI2,HLF,ACOT7,LRRC75A,SHISAL1,IBA57,TUBB2B,METTL21A,KCNH2,KCNJ16,GATD1,KIT,L1CAM,STMN1,LYPLAL1,MATK,AQP11,ADAM11,MOV10,BLOC1S2,MYBPC1,MYCN,FXYD6,NDUFA5,RCOR2,NEFM,PDE3B,PDE4A,PDE1B,SSH1,PKM,SMOX,EPN1,PRIMPOL,POLR2F,FSD1,PPP1R1A,PPP5C,CEP41,MAPK4,PROX1,MASP1,LAMA1,UHRF1BP1,ELOVL2,SPDL1,EML5,PTPRG,NKAIN1,TMEM231,CCDC40,ROGDI,NUDT11,ROBO2,PCMTD2,RIMKLA,RPS6KA2,YJEFN3,RTN1,TRAPPC13,SCN2B,SCN8A,HES6,ZNF821,COPZ1,SCG5,SH3GL3,FHOD3,ST6GAL1,SLC4A3,CXXC4,SNAP25,SCN3B,SOX11,SST,ZC4H2,LRRC4,STX1A,KANK1,SYT5,MTCL1,TBCEL,WSCD1,CUX2,TCF7,ZFPM2,ARL10,PRMT8,DCBLD1,TSN,HSPBP1,CADM1,SLAIN1,CCDC136,VLDLR,SF1,SPHK2,ANKS1B,SLC38A1,RGMA,CIAPIN1,PPP1R3F,PLD4,FZD3,MARCH8,AP3B2,SPATA13" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_1000 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.34E-04 1.00E+00 3.62E-03 3.30E-02 18 51 "CPNE2,HECW2,QKI,HAPLN1,ELMO1,LPAR6,ST3GAL6,FYN,RAPGEF4,PDE2A,ABCB1,MDGA2,ZNF532,SEMA6D,FAM102A,PEG10,HEY1,NHSL1" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k1_200 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.39E-04 1.00E+00 3.64E-03 3.32E-02 17 47 "FMNL2,DCLK1,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,GABRA4,GABRB1,KITLG,MTR,TNFRSF19,STUM,SLC4A3,KDM3A,ACTR6" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K4 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 8.44E-04 1.00E+00 3.66E-03 3.34E-02 50 197 "ACTN2,ADCY2,KIAA1324,ARHGAP20,LGR5,ADGRB2,C1QC,LDLRAD4,REPS2,KCNAB3,CSF1R,DLG2,DRP2,RASA4,EPB41L1,EPS8,FYB1,ARPP21,TMEM8B,NTNG2,GLRB,GSN,IL11RA,GPR155,NEXMIF,NELL1,NPR2,PDE4D,PLCL1,TRHDE,NXPH1,PRKAR1B,ZCWPW1,ZNF493,ZMAT4,PRIMA1,MYH14,MRAS,ASAP3,SLC1A2,SLC6A9,ACSBG1,ZFR2,UNC5D,ADGRL3,FAM189A1,CADM2,LRP8,PCDH15,DPF3" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_100 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 8.54E-04 1.00E+00 3.70E-03 3.37E-02 26 85 "NR0B1,PPP4R4,TMEM108,CALB1,DCLK1,PLXNA4,DOCK4,DRP2,PLXNC1,EMX2,GABRA4,FREM1,KCND2,KLHL23,MAP2,PDGFRA,PCDH18,TMEM255A,TMEM206,SMOC1,ADGRL3,TEX15,ACTR6,TNNT1,VSNL1,LYPD6" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_200 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.60E-04 1.00E+00 3.72E-03 3.39E-02 10 21 "NSG1,TPPP3,GNG3,TAGLN3,NNAT,SLC10A4,PRPH,SST,TMEFF2,UCHL1" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200_k1 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 8.60E-04 1.00E+00 3.72E-03 3.39E-02 10 21 "BMP7,CALB1,CRLF1,DUSP9,EMX2,SPSB4,RASL10A,KIF5C,LAMA1,PRR5L" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.70E-04 1.00E+00 3.76E-03 3.43E-02 32 112 "ABAT,PNMA8B,APOC1,LGR5,CDC14B,CDH2,CLU,DCT,SRGAP3,PLXNC1,FAM198B,AFF2,SEPT9,GATM,GPR37,BVES,SHISA6,SYTL4,MOV10,NEXMIF,PRKCB,TMEM206,SOX6,ST8SIA1,TNIK,TSPYL2,SMOC1,OBSL1,BEX4,TST,NAV2,WNK3" Coexpression Atlas gudmap_RNAseq_p2_Glomerlular Endothelial_2500 gudmap_RNAseq_p2_Glomerlular Endothelial_2500 Gudmap RNAseq 8.78E-04 1.00E+00 3.79E-03 3.46E-02 324 1686 "CPNE2,ACHE,AS3MT,ADCY6,TMCC3,RNF157,ADD2,SLC12A5,ADORA2A,ESYT2,MTUS1,HECW2,C1QTNF1,ADGRF5,LTBP4,PITPNM2,AMPD3,SEMA7A,PI16,ANXA7,APBB2,GAS7,DGKZ,APP,ARNTL,ARRB1,PDE8B,MARK4,NUMB,ATP1A1,ATP1B3,RIPK1,ADAM15,NRP2,GPR146,CFLAR,ST3GAL5,ARHGEF7,RAB29,LDLRAD4,CA8,THSD7A,CAMK2D,CH25H,HIP1R,LDB2,FMNL3,SCARB1,CD38,CD81,ARHGEF2,KCNAB3,CCPG1,UBE2L6,ADGRG1,JAM2,TAOK2,PPT2,CLU,CLTB,QKI,TMEM184B,CABP1,IFFO1,MYRIP,MFSD4A,CP,CLOCK,CDC42BPB,C2CD2,CREM,AKAP12,ANKRD44,GDA,ABCG1,AATK,CSF1,FEZ2,LRRC3B,MICAL2,SOCS5,CST3,PLXNA4,PPP1R16B,SDC3,CYBB,DOCK4,MYADM,RIPOR2,KIF26A,ACY3,PITPNC1,RUSC2,C2CD2L,TMCC2,CPEB2,SLC12A6,RCAN1,GNE,ARRDC4,ECM2,EBF1,SNX29,EDN1,EDNRB,SYT15,KLHL5,TMTC1,FRY,OPTN,EGR3,SORBS3,IRAK4,ELN,EML1,CALCRL,PLEKHO1,RASGRP2,KCNMB2,STX2,NCALD,CEP85L,RCSD1,EZH1,HSPA12B,REEP2,F8,CORO2B,DLC1,ATP8A1,ST3GAL6,CHST15,TOMM40L,FCGRT,FGF1,FGFR3,BAIAP2,VTI1B,IQCG,ZMYND15,FLT1,SORBS1,PDLIM5,CAMKK2,ST6GALNAC3,SARAF,FYN,GALNT15,IP6K3,ERAP1,INPP5K,GATM,GCNT2,PCDH17,GGTA1P,NTNG2,RND1,FERMT2,ATF7,CCDC184,STON1,RAPGEF4,STMN2,RAPGEF1,SERP2,NR3C1,GSTM5,GSTT2,IRAK3,RASSF8,GABARAPL2,ICA1,IFI16,IL6ST,INPP1,INPP5B,LRRTM3,ITPKB,JAK1,KCNJ5,KHK,KIFC3,KLC1,INSYN2,LIFR,LMO2,VWA5A,NCOA7,MAPT,MBNL1,MEF2C,MEIS2,KITLG,MMP17,CD200,CCDC80,MX1,LAYN,MYO6,MYO7A,IDNK,NOVA2,CLEC9A,P2RX7,P2RY1,PBX1,PCSK5,PDE2A,PDE3A,PDE4A,PFKP,SERPINI1,PIK3CD,CCSER2,PKD1,PLEC,PLTP,SPATA6,SEPT4,DRAM2,MINDY2,PPP3CA,PPP3CC,MAPK3,SNRK,TMEM104,PXK,PTPRB,CASTOR1,PTPRG,PYGM,RIPOR1,RAB5B,PLEKHB2,SH3TC2,C1orf54,RASGRF2,ZDHHC14,BSDC1,RGS3,KLHDC8A,CYB561D1,PCMTD2,RPS6KA2,EMID1,LRRK2,PTGR2,MAPK12,SEMA6D,SCP2,PEAR1,SEC14L1,SGK1,PPM1E,FAM81A,PREX2,EPN2,SMTN,LIMS2,SLC15A2,EFHD1,CPEB4,ABTB1,LIMCH1,LMBRD1,FAM219A,TEX2,UNC5B,ARHGAP26,DBNDD2,SPTAN1,IQSEC2,COLGALT2,THSD1,RGL1,STAC2,PHLDB1,STXBP1,C3orf70,PLCB1,ARC,SYPL1,TACC1,MCF2L,TAL1,PDLIM2,WSCD1,SYNE1,DOCK9,PSD3,ARHGEF12,TNS2,CYB561A3,TEK,CHST8,TGFBR3,ENHO,TIAM1,TIE1,HEY1,TK2,TLR4,HEY2,LRRC8A,TNS1,IL34,TRPC1,DCBLD1,TUBB2A,SGK3,UCHL1,FAM181B,MTCH1,NPDC1,AGMO,SLC26A10,LYPD6,GDPD5,PLSCR4,MSRB3,SSPN,KLHDC1,PIANP,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500_k3 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.82E-04 1.00E+00 3.81E-03 3.47E-02 30 103 "PI16,ATP1A2,ADAM23,GPR146,CACNA2D1,ENTPD2,OSBPL3,MFAP3L,CHRDL1,ABCC9,HIPK3,PCOLCE2,MRVI1,NRN1,CAP2,DKK3,DNER,GCNT2,HLF,KCNA1,KCNF1,MBP,RGS4,TTLL7,SCN7A,SYN2,RGMB,AGMO,PLSCR4,FAM13C" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k4 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.84E-04 1.00E+00 3.81E-03 3.47E-02 86 379 "ACTN2,ALAD,ARHGAP20,APOC2,MMD2,RGN,MYOM2,CDC25B,UBE2L6,IFFO1,CPS1,TMCC2,DUSP9,SGK2,AASS,SRPK3,EPB41,DMTN,PIPOX,F5,CORO2B,FECH,FOXG1,FOXO3,SPECC1,BRPF3,ARPP21,MYOZ2,ALDH1L1,RAB40B,GRIA1,GRIA4,MAEL,ARHGAP36,C2orf72,IGFBP1,IGSF1,ITIH2,LMO2,LSS,ASPRV1,MAOB,MEF2C,MTTP,MTR,MYBPC1,MYH3,MYH6,MYH7,MYL3,PAH,PSAT1,MASP1,RELN,PTX3,MORC4,LGI2,ATP8B4,MEG3,ELMOD1,SLC30A10,SOX6,ARX,ABLIM3,SLA,YPEL4,SLC22A4,SLN,SNCA,APOM,ADHFE1,COBL,TAL1,VWC2,ARHGEF12,VWCE,TF,THBS4,TMOD1,TPM3,TTPA,PDIA2,ZIC1,ZIC3,TCEAL7,SPIRE1" Coexpression Atlas ratio_SC_vs_ECTO_1000_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 8.98E-04 1.00E+00 3.86E-03 3.52E-02 38 140 "ADCY5,SPARCL1,ZFYVE28,PLA2G4C,ATP1A3,AZGP1,LDHD,DIRAS1,RUNX1T1,LDB2,CRYM,FAM78B,EEF1A2,HSPA12B,ALDH1L1,GNAO1,RAPGEF4,NEGR1,ITGAM,KCNK1,MT1M,MX1,TMEM38A,ST8SIA5,FXYD1,PLTP,SGSM1,SCN4B,SSTR1,SYN2,POPDC3,TEK,TIMP4,RASD2,VIPR2,SLC30A3,PMEPA1,SHD" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.98E-04 1.00E+00 3.86E-03 3.52E-02 38 140 "C6orf89,CBLN1,CCK,CHGA,CHRNB2,CLIP3,ATL1,BSCL2,APC2,REEP2,TUBB4A,CORO2B,PCSK1N,GNG3,GPR17,GSTM5,CELF3,ATCAY,KCNJ3,KCNN2,PACRG,PCBP3,SLC10A4,PPP1R1A,PRPH,RALGDS,CRTAC1,RIT2,SST,STX1A,GSE1,SYN1,USP22,SSBP2,TMEFF2,MTCH1,NPDC1,PCBP4" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Migrating MyoFibroblast_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Migrating MyoFibroblast_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 9.11E-04 1.00E+00 3.91E-03 3.57E-02 63 262 "ACTN1,NDRG2,SPARCL1,LTBP4,CACNB2,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,GPSM1,DOCK4,ZEB2,EDNRA,EDNRB,PCOLCE2,LRRC17,NCALD,ETV1,FHL1,FOXF2,DKK3,ZMYND11,FREM1,SPIN1,FERMT2,GPM6B,GRB10,NR3C1,GSN,GUCY1A1,GYG1,WIF1,IGF1,IL11RA,LAMA2,LDLRAD3,NNAT,DDR2,PBX1,PDGFRA,ENPP2,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,DZIP1,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,TUBA1A,ADAMTS10" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Migrating MyoFibroblast_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Migrating MyoFibroblast_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 9.11E-04 1.00E+00 3.91E-03 3.57E-02 63 262 "ACTN1,NDRG2,SPARCL1,LTBP4,CACNB2,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,GPSM1,DOCK4,ZEB2,EDNRA,EDNRB,PCOLCE2,LRRC17,NCALD,ETV1,FHL1,FOXF2,DKK3,ZMYND11,FREM1,SPIN1,FERMT2,GPM6B,GRB10,NR3C1,GSN,GUCY1A1,GYG1,WIF1,IGF1,IL11RA,LAMA2,LDLRAD3,NNAT,DDR2,PBX1,PDGFRA,ENPP2,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,DZIP1,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,TUBA1A,ADAMTS10" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K5 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 9.21E-04 1.00E+00 3.95E-03 3.60E-02 76 328 "ERMN,ZNF608,APOC1,ARRB2,TMEM108,ATP2B1,TTLL9,BCHE,INA,ARHGEF1,LRRFIP1,CBARP,CLCN3,TJP2,ZNF385A,AKAP12,LRRC3B,CHRDL1,ST8SIA3,SEZ6,STX2,NCALD,RRAGB,CEND1,TUBB4A,FGF11,NOP56,SYT3,COQ5,SALL3,CSDC2,KIAA1958,GPD2,GRIK5,LRRC75A,HSP90AA1,SHISAL1,LRRTM3,SLC35G1,CDH20,KCNK1,KIT,MAOB,CCDC80,IGSF11,SNX10,PMP22,MAGEL2,NXPH1,FSD1,NKAIN4,RELN,PTPN13,CEP97,SUSD4,STK32B,PTGR2,YJEFN3,SALL1,MAPK12,NTNG1,CCDC92,SNRPN,LARP4,KANK1,ROBO3,OBSL1,DCBLD1,TST,CADM1,CCDC14,CA10,SHD,RGMA,NAV2,TMEM163" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.35E-04 1.00E+00 4.01E-03 3.66E-02 43 164 "ADCY5,ANK1,ATP1A2,MYOM1,NRP2,CACNA2D1,CAMK2D,DMPK,CPEB2,MRVI1,SORBS1,IGSF5,PRUNE2,BVES,HNMT,IFI16,IL6ST,IL17D,NPTX2,HCN1,PFKP,PRKCB,PTHLH,RYR3,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,SMTN,LIMS2,RIMS1,DBNDD2,POPDC3,ENHO,TNNT1,TPM2,SYNPO2,PPIL6,RBFOX3,RGS7BP,ACTR3B,MSRB3" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_200 kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.37E-04 1.00E+00 4.01E-03 3.66E-02 39 145 "KLHL32,PCDH19,SEMA6A,PROM1,CALB1,B4GALT6,HAPLN1,FAM169A,TOX,PLEKHA1,EMX2,EN2,ACSL4,GAP43,IGSF5,GFRA1,MAP7D2,GNG3,HAS2,LIX1,KIT,KITLG,PRTG,FAT3,EML5,PTPRZ1,TMEM255A,RET,MORC4,NUDT11,PREX2,BEX1,NUDT10,KLHL4,CUX2,BEX4,CA14,CADM1,VSNL1" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_500 dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.37E-04 1.00E+00 4.01E-03 3.66E-02 39 145 "FMNL2,SLITRK1,NR0B1,PPP4R4,ATP2B3,CACNB2,SLC16A4,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,DRP2,KLHL5,EMX2,EPB41L1,GABRA4,PCDH11X,PACSIN2,KLHL23,MYO9A,SERPINI1,REV3L,LGR4,HUNK,ST8SIA1,SLC4A3,SNCA,UHRF1BP1L,SMOC1,ST5,ADGRL3,OBSL1,DNAH7,ACTR6,TNNT1,FNDC5,ZNF23" Coexpression Atlas GSM605865_500 "Myeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 9.38E-04 1.00E+00 4.01E-03 3.66E-02 97 437 "ALCAM,BCAR3,ABCD2,GAS7,APOC2,APP,SHTN1,PDXK,CASK,ATP1A3,ATP6V0A1,NRP2,C1QC,MS4A7,B4GALT6,TPP1,LY86,GDA,CSF1R,CSF3R,CST3,SDC3,CTNND1,CYBB,MYADM,DBI,SIRPA,ZEB2,EDNRB,PLXNC1,EPB41L1,EPS8,IGSF6,TLR7,SIRPB1,FAM198B,FCGR1A,FCGR3A,FCGRT,PCYOX1,FOLR2,AK8,TPPP3,GALC,GATM,HPGDS,GLUL,KIF3A,ATG4C,HNMT,IGF1,LRRC25,DOCK7,ITGAM,TTYH2,LAMP2,VWA5A,MITF,MSR1,MYO5A,NCF2,OPHN1,P2RX7,TREM2,PLTP,PMP22,LRP12,SLC36A4,DRAM2,RASGEF1B,GDPD1,PTAFR,MTMR10,RAB3IL1,PID1,C1orf54,RNH1,ACER3,ITSN1,SLC11A1,SPP1,RGL1,SULF2,FGD4,SLC37A2,DMXL2,KIAA0930,TPCN2,TF,TLR4,TNS1,TPD52,LAT2,AGMO,SNX27,PLD4,MARCH8" Coexpression Atlas ratio_MESO_vs_SC_1000_K2 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 9.47E-04 1.00E+00 4.05E-03 3.69E-02 36 131 "C1QTNF1,CFLAR,CAMK2D,PLCXD3,GPSM1,DYNC1I1,DTNA,FAM198B,TPPP3,GGT5,PPARGC1A,HP,KCNJ3,KIFC3,MITF,MSR1,MT3,MYL3,SLCO1C1,NPPA,PALM,PMP22,PTH1R,RNASE1,TMEM100,SH3BGR,CCDC92,SLC1A7,SMARCD3,TNS2,ZFPM2,TGFBR3,TMOD1,VLDLR,ZBTB16,ADAMTS9" Coexpression Atlas gudmap_developingGonad_P2_ovary_500 DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.62E-04 1.00E+00 4.11E-03 3.74E-02 86 380 "TKTL1,TMCC3,PNMA8B,LCORL,PKP4,LGR5,PLA2G4C,BACH1,ST3GAL5,CHM,CLU,ABI3BP,MYRIP,RBM39,GDA,TENM4,CSNK1E,PLXNA4,GSDME,SNAP91,G3BP2,SLC12A6,ATL1,PLXNC1,EIF4G1,ELAVL2,EPB41L2,LRRC17,SCML2,ILDR2,DNER,GATM,GDF9,MAP7D2,LPAR4,KIF3A,MAEL,SHISA6,KIT,SYTL4,CHIC1,MMP16,RSPO2,MYO5A,NEXMIF,NOS1,SETD4,PDPK1,ABCB1,PLP1,MAPK10,GDPD1,STK32A,SUSD4,TMLHE,MEG3,FNIP1,IL17RB,ARX,KIF16B,CPEB3,SYBU,SLC12A2,SLC14A1,CPEB4,MYT1L,ZC3H13,RBM26,CLSTN2,SYNE2,ANKRD12,CAMTA1,DMXL2,TEX15,MTMR14,CBX5,PARD3,SSBP2,UCHL1,TBC1D15,TRIM9,NDRG4,ADAMTS9,FAM47E,DPF3,GAN" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_200 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 9.62E-04 1.00E+00 4.11E-03 3.74E-02 21 64 "HECW2,AMH,SEMA7A,ARHGDIG,CADPS,CACNA2D2,CLU,ELMO1,DTNA,MRO,CERCAM,EPS8,ERBB4,FGF13,SEMA6C,PAK3,SERPINE2,RASGEF1B,EFHD1,TACC1,SGK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500 DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.63E-04 1.00E+00 4.11E-03 3.74E-02 91 406 "ACTN2,BBOX1,ANK1,APOC2,BCAS1,GPR146,MMD2,RUNX1T1,RGN,MYOM2,UBE2L6,CHGB,COL9A1,COL9A3,CPS1,CRYM,TMCC2,EBF1,SGK2,SH3GLB1,AASS,ELAVL4,SRPK3,DMTN,F5,FABP7,CORO2B,FECH,SPECC1,MEGF10,ARPP21,ACSS1,MYOZ2,GFRA2,LYVE1,RAB40B,STMN2,GRIA1,MAEL,ARHGAP36,NEGR1,IFI16,C2orf72,IGFBP1,INSM1,ITIH2,LMO2,MAOB,MAP4,MEF2C,MYBPC1,MYH3,MYH6,MYH7,MYL3,CLDN11,PAH,PGAM2,MAPK10,PRPH,RELN,RGS4,ZFHX4,SALL1,SCN7A,SLC30A10,SOX6,SH3BGR,ABLIM3,YPEL4,SLC14A1,SPHKAP,SLC22A4,SLN,SNAP25,SNCA,SCN3B,SOX2,APOM,TAL1,VWC2,TF,THBS4,TMOD1,TNNT1,SYNPO2,TTPA,PDIA2,ZIC1,AGMO,TCEAL7" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_500 DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.63E-04 1.00E+00 4.11E-03 3.74E-02 91 406 "PLEKHH1,GRAMD1B,ADORA1,PCDH19,DOC2A,EPB41L5,LGR5,CDC14B,BMP7,CA4,CANX,CLDN10,CD38,TENM4,KIAA0040,CTH,GREB1,ARHGAP24,SCRN1,SMG7,NTM,DUSP9,HIPK3,HEYL,EIF1,EMX2,RASGRP2,EPHB1,ST3GAL6,SPSB4,FGFR1,FLT1,SGIP1,CGREF1,ILDR2,GALC,SALL3,SYT17,IGSF5,GCNT2,PCDH17,AIFM3,ADGRA3,B4GALNT4,GPER1,GRB10,TMEM25,FAM107A,HP,IGSF1,HES5,KCNC2,KCNJ16,TTYH2,CLEC18A,TM6SF1,KITLG,VWA2,NRCAM,OXTR,ENPP2,PIK3C2A,RETREG1,PLXNB1,SCHIP1,MBOAT7,KANSL1,MAPK4,LAMA1,ELOVL2,PTPRO,RIPOR1,NKAIN1,EMID1,LGR4,SALL1,SCN8A,LINC00461,FHOD3,FAM81A,DDN,APOM,STX1A,TMEM150C,CAMSAP2,WWC1,WSCD1,HEY1,ERCC6L2,TMEM178A,SPATA13" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.64E-04 1.00E+00 4.11E-03 3.74E-02 51 203 "RALGAPA1,FAM135A,OGT,APC,PHYHD1,CACNA2D1,CANX,CFL2,DZIP3,CPEB2,KMT5B,EIF5,EIF1,MED12L,KIAA1109,SUCO,SYNCRIP,SMC2,PDLIM5,NR3C1,KAT7,KIF2A,MKLN1,CCDC80,NCAM1,NEK1,NFIA,CNOT4,PIK3C2A,KANSL1,PKN2,DPF2,REV3L,TRA2B,SCMH1,SORCS3,KIF1B,CLASP2,EPB41L3,PRRC2C,VPS13A,CAMSAP2,MGRN1,R3HDM1,RBFOX2,RGMB,SSBP2,VLDLR,FMN2,LMAN2L,GOPC" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_1000_k4 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.76E-04 1.00E+00 4.15E-03 3.79E-02 85 375 "RALGAPA1,ABHD6,TAOK1,FAM135A,OGT,ANK3,APAF1,APC,EPB41L5,DGKD,TNRC6C,SLC4A4,WASF1,CACNA2D1,CANX,DCLK1,CFL2,CLCN3,COL4A5,RBM39,DZIP3,PLPPR4,SEMA3D,EIF5,EZH1,MED12L,KIAA1109,SUCO,SYNCRIP,SMC2,PDLIM5,DKK3,AHCYL1,IQGAP2,TUBGCP4,SRCAP,PPARGC1A,GRB10,ICA1,IL6ST,TUBB2B,KIF2A,CHIC1,KITLG,MKLN1,PENK,PFKFB2,PIK3C2A,PSAT1,SCHIP1,PMS2,KANSL1,PKN2,MAPK8,REV3L,RFX5,SFPQ,ASRGL1,TRA2B,PPP1R9A,RUFY2,SLC8A1,SCMH1,LIMCH1,FAM126B,BDP1,ZHX3,MYCBP2,KANK1,PRRC2C,VPS13A,CAMSAP2,MGRN1,WASHC4,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,UGT8,VLDLR,FMN2,DOCK8,NUP214,SOCS4" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_1000 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.01E-03 1.00E+00 4.28E-03 3.90E-02 64 268 "FMNL2,KLHL13,EPB41L5,LGR5,PPP4R4,INSYN2B,ATP2B3,WASF1,BTRC,CACNA1D,CACNB2,SLC16A4,MAGI1,CHRM4,PLXNA4,DAPK1,RASGRP1,KLHL5,ABI2,EMX2,EPB41L1,NRN1,GABRA4,GABRB1,GRIK5,IL6ST,KLHL23,MAOB,KITLG,SESN3,MYO9A,NEXMIF,SLC11A2,SERPINI1,PPARA,PPP3CC,GDPD1,FAT4,ZFHX4,PRCD,TNFRSF19,STUM,ABLIM3,SLC4A3,SCMH1,ATF7IP,KDM3A,LHPP,ST5,SLC37A2,RPGRIP1L,CCDC173,DNAH7,ACTR6,KAT6B,TNNT1,FNDC5,VAV2,ZNF23,ELFN1,LYPD6,REEP1,NAV2,FRMD6" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.01E-03 1.00E+00 4.28E-03 3.90E-02 157 759 "RALGAPA1,ACADM,PLEKHH1,GRAMD1B,OSBPL6,OGT,C6orf89,EPB41L5,DGKD,CDC14B,ASPA,SLC4A4,CFLAR,CA4,CA12,CACNA2D1,CANX,ISPD,MAP7,CLDN10,USP2,SLC16A4,SLC22A6,CLCN3,CLTC,FAM189A2,SLC35F1,OSBPL3,IPCEF1,CTH,ARHGAP24,DNAJC6,GUCD1,SMG7,SNAP91,RABGAP1L,GOLT1B,USH1C,SGK2,EIF4G2,PAN3,EMX2,PIPOX,ZMYND10,SPSB4,FGFR3,SYNCRIP,SEMA4D,ATP13A4,SGIP1,FOLR2,CGREF1,FUT9,PHYHIPL,ILDR2,GALC,RAPGEF6,IGSF5,ALDH1L1,GHR,PPARGC1A,GJB1,BRD8,GK,AIFM3,CNDP1,GPD1,GRB10,TMEM25,HPS5,DHX35,IGFBP1,KCNC2,KCNJ16,PAXBP1,NCOA7,C2orf80,GPR155,CLEC18A,MAP4,AQP11,MITF,MYO6,MYO7A,MYO9A,SLC11A2,SETD4,IGSF11,PAH,PC,PDE1C,ENPP2,PIK3C2A,RETREG1,PRIMPOL,ANKRD16,DRAM2,POU6F1,KANSL1,RANBP3L,MAPK4,BCAS3,LAMA1,PTH1R,ELOVL2,PTPN13,EML5,SH3TC2,SLC6A15,REV3L,LRRK2,LGR4,RYR3,SALL1,HOGA1,SCN8A,IL17RB,SUPT20H,KIF21A,PPP1R9A,FHOD3,SLC15A2,FAM126B,SPATA7,ZHX3,MYCBP2,SPP1,RBM26,NPAS3,PBLD,COLGALT2,APOM,NEK4,ADHFE1,PRRC2C,VPS13A,SEMA4A,CAMSAP2,FAM208A,WWC1,SATB2,WASHC4,VWCE,ZFP91,ERCC6L2,LRRC8A,RGMB,TRIO,AMACR,TRPS1,PPIL6,UGT8,VLDLR,SLC13A3,ADAMTS9,SEMA3B,KLHDC1" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_1000_K4 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.01E-03 1.00E+00 4.30E-03 3.92E-02 60 248 "ERMN,TMEM108,TTLL9,BCHE,CA4,CA12,CBLN1,CCNT1,INA,ARHGEF1,LRRFIP1,CLCN3,LRRC3B,CHRDL1,ST8SIA3,SEZ6,NCALD,PIPOX,CEND1,TUBB4A,FGF11,NOP56,SYT3,COQ5,SALL3,CSDC2,CECR2,GRIK5,HSP90AA1,SHISAL1,CDH20,CCDC80,IGSF11,PRTG,SNX10,PLTP,PMP22,MAGEL2,NXPH1,FSD1,NKAIN4,RELN,GDPD2,PTPN13,STK32B,PTGR2,YJEFN3,SALL1,NTNG1,SNRPN,BEX1,C11orf87,AJAP1,MTCL1,ROBO3,BEX4,CCDC14,ZIC2,CA10,RGMA" Coexpression Atlas GSM538277_500 "Myeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.03E-03 1.00E+00 4.36E-03 3.98E-02 87 386 "CPNE2,ACTN1,FMNL2,DSCAML1,ADCY6,TMCC3,GRAMD1B,ADORA2A,SEMA7A,APP,SHTN1,CASK,ZBTB10,CADM3,N4BP2L1,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,CLU,LY86,SLC4A8,ABCG1,ATRNL1,PNPLA8,CTNND1,RUBCN,RASSF2,SIRPA,RABGAP1L,DSCAM,EFNA2,PLXNC1,RASA4,CALCRL,ENO2,CDHR1,EXTL1,ZMYND15,NEK6,MALT1,RAB30,ADAP1,SLC2A6,GYG1,HSF2,DOCK7,SCIN,INSM1,JAK2,KTN1,ASPRV1,ADAM11,MYO5A,NPR2,PFKFB3,CDK14,CCSER2,PLCL1,SLC22A23,PTAFR,PLEKHB2,ROGDI,PRR5L,SEMA6D,SCN4B,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,ST5,SULF2,ARHGEF9,TMEM150C,ARC,ATP11A,PHF24,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,SPIRE1,WNK1,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_100 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.04E-03 1.00E+00 4.39E-03 4.00E-02 26 86 "EMILIN3,DPP10,RUNX1T1,CDH10,JAKMIP2,FOXF2,GFRA1,GRIA2,RSPO2,MYH3,NDP,CLDN11,PRRX1,FAT3,REV3L,ZFHX4,SALL1,SCN3A,SLC15A2,SOX2,SMOC1,EPB41L3,HHIP,RBFOX2,RGMB,SYNPO2" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_200 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.04E-03 1.00E+00 4.39E-03 4.00E-02 42 160 "SLC12A5,AMPH,ADAM23,CDH2,COL9A1,CRMP1,CRYM,PPP1R16B,CTH,SPOCK2,SNAP91,DUSP9,EFNA3,ELAVL4,KCNMB2,CDHR1,EYA1,SPSB4,PRELID3A,TVP23A,GABRA1,CHL1,GALC,FAM19A2,FAM107A,HAS2,KIF5C,NELL1,PCDH8,PRTG,GAL3ST4,SALL1,MAPK12,CSRNP3,ANKRD6,SLC9A5,CLSTN2,AKNA,ASXL3,CA14,LRP8,NETO2" Coexpression Atlas GSM538258_500 "Myeloid Cells, DC.8+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-2" "Immgen.org, GSE15907" 1.04E-03 1.00E+00 4.42E-03 4.03E-02 91 407 "CPNE2,FMNL2,ADORA3,RNF150,ADRB2,ALCAM,FGD2,SHTN1,ARHGAP5,ADAM23,ST3GAL5,CACNA1E,CD86,SCARB1,CD81,ARHGAP22,ZFYVE9,LY86,FAM149A,ZNF385A,CDC42BPB,CSF2RA,CST3,SDC3,CTNND1,CYBB,DOCK4,HDAC9,DBN1,SRGAP3,ARRDC4,PLXNC1,RASA4,PLEKHA1,PLEKHO1,EPS8,IGSF6,FCGRT,OLFM1,FGR,FLT1,NEK6,GATM,RAB30,MAP4K5,HPS5,IRF8,LRRC25,DOCK7,JAK2,KIT,LIFR,ASPRV1,ADAM11,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,PFKFB3,CDK14,PRKAB2,RASGEF1B,RAB39A,SLC22A23,PTAFR,MARCH1,PID1,C1orf54,ROGDI,SNX22,PRR5L,ACER3,LRRK2,KCNIP3,RTN1,MRAS,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,FNBP1,RGL1,SULF2,SEPT3,ADGRL3,CYB561A3,TRPM2,CADM1,PLD4,PIANP" Coexpression Atlas gudmap_kidney_adult_Mesangium_Meis_k1_1000 kidney_adult_Mesangium_Meis_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.05E-03 1.00E+00 4.42E-03 4.03E-02 35 127 "OSBPL8,C1QTNF1,BCAR3,CDC42BPA,ARRB1,CD81,CLOCK,EML1,CEP85L,ST3GAL6,NPTN,GGT5,FERMT2,RASSF8,ZHX1,IL6ST,GPR155,MAPT,CCSER2,PKIA,PTH1R,FAM184A,ZDHHC14,WLS,CPEB4,LMBRD1,PSD3,ARHGEF12,TNS2,FRYL,TGFBR3,TJP1,DAAM2,PLEKHH2,SPIRE1" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.05E-03 1.00E+00 4.42E-03 4.03E-02 14 36 "EPB41L5,CDHR1,ST3GAL6,IGSF5,FREM1,KCNA1,CLEC18A,TM6SF1,OXTR,PRR5L,SALL1,ANKRD6,NEK4,HEY1" Coexpression Atlas gudmap_developingKidney_e15.5_anlage of loop of Henle_500 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.06E-03 1.00E+00 4.48E-03 4.09E-02 90 402 "RALGAPA1,ABHD6,BEND6,ANK3,APC,EPB41L5,DGKD,TNRC6C,SLC4A4,MTMR3,CA4,CACNA2D1,CALB1,CANX,MAP7,CLDN10,CLCN3,NCOR1,CRYM,MFAP3L,ARNT2,DNM2,GOLT1B,SGK2,ST3GAL6,MED12L,SYNCRIP,SMC2,GABRA1,GALC,SYT17,IGSF5,GCNT2,GFRA1,PPARGC1A,TMEM25,FAM107A,IGFBP1,SCIN,KCNC2,KCNJ16,KCNK1,KIF2A,NCOA7,CLEC18A,CHIC1,MITF,MKLN1,NCAM1,CNOT4,NRCAM,PDE1C,PENK,PFKP,PDZRN4,SCHIP1,PRRX1,KANSL1,MAPK4,MAPK8,CNNM2,PTPRO,RASGRF1,REV3L,SALL1,SCN8A,ZFP2,FHOD3,NAPB,SLC15A2,SORCS3,FAM126B,ZHX3,MYCBP2,DDN,PRRC2C,CAMSAP2,WWC1,MGRN1,WSCD1,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,UGT8,VLDLR,ADAMTS9,TMEM178A,DOCK8" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_200 dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.07E-03 1.00E+00 4.50E-03 4.10E-02 43 165 "NR0B1,SHTN1,LGR5,PPP4R4,PDE8B,INSYN2B,CACNA1D,DCLK1,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,DRP2,EMX2,NRN1,GABRA4,GABRB1,PLD5,KCND2,KLHL23,MAOB,KITLG,MTR,MYO9A,PDE1A,CDK14,PCDH18,GDPD2,TMEM206,TNFRSF19,STUM,SLC4A3,KDM3A,UHRF1BP1L,SMOC1,ADGRL3,ACTR6,DAAM2,TNNT1,FNDC5,WNK3,FRMD6" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k3_1000 dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.07E-03 1.00E+00 4.53E-03 4.12E-02 98 444 "CCDC85A,ADORA2A,ADGRF5,SPARCL1,SEMA6A,APBB2,DGKZ,UPRT,SHROOM2,ARRB1,DOCK11,ADAM15,NRP2,ARHGEF7,LDB2,FMNL3,CD38,ARHGEF2,MS4A7,TAOK2,TMEM184B,MAP4K4,CREM,CRMP1,CSF1R,CYBB,RASSF2,GIT2,DBN1,PITPNC1,EBF1,SH3GLB1,CALCRL,PLEKHO1,RASGRP2,STX2,DENND4A,CORO2B,DLC1,KIAA1109,FLT1,PDLIM5,TRIM16,GAP43,PCDH17,GGTA1P,LILRB4,LPAR4,RAPGEF4,MAP4K5,NCKAP1L,ICA1,INSYN2,LMO2,TM6SF1,MEF2C,MEST,MYO6,CLEC9A,OPHN1,PALM,PDE2A,PDE4B,PDE4D,GNG2,SPATA6,DRAM2,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,PRR5L,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,UNC5B,THSD1,STXBP1,PLCB1,TCF4,DOCK9,TEK,TF,TIE1,TJP1,RFTN2,WIPF1,NAV3,FAM13C,DOCK8,JMJD1C,RNF146" Coexpression Atlas gudmap_developingKidney_e15.5_1000_k4 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.08E-03 1.00E+00 4.55E-03 4.15E-02 18 52 "CRYM,NTM,CDHR1,ST3GAL6,SGIP1,GABRA1,IQGAP2,FAM107A,SCHIP1,RELN,PTPRO,ROBO2,SALL1,SCN7A,SLCO1A2,DDN,STX1A,TMEM178A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.08E-03 1.00E+00 4.55E-03 4.15E-02 18 52 "PCDH10,INSYN2B,RUNX1T1,DCLK1,CDO1,DLX1,TMEM132C,SGIP1,MEGF10,GABRA4,GABRB1,WIF1,MYH3,PRRX1,ZFHX4,PRR5L,TAC1,UNC5D" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k2_1000 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.08E-03 1.00E+00 4.55E-03 4.15E-02 51 204 "ABAT,NR0B1,KCNT1,LGR5,CDC14B,PPP4R4,ATP2B3,RGS11,SLC16A4,CDH2,AKAP5,PLXNA4,GPRASP1,DAPK1,DBI,DCT,SRGAP3,TSPAN5,MTSS1L,AFF2,GAB1,SHISA6,LRRTM3,KLHL23,TTYH2,MATN2,KITLG,AFF1,MTR,NFIA,ETFRF1,SERPINI1,PPP3CC,PRKCB,PTPN13,TMEM206,FRMPD1,ST8SIA1,SOX5,UHRF1BP1L,TSPYL2,SMOC1,ST5,FGD4,MTCL1,OBSL1,ZFPM2,FNDC5,TST,NAV2,WNK3" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_500_K2 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.09E-03 1.00E+00 4.57E-03 4.17E-02 15 40 "SLITRK1,BMPR1B,DIRAS1,ADGRG1,ST18,SPOCK2,DLX1,SHANK1,TMEM35A,AFF2,B3GAT1,MFSD2A,POU6F1,PEX26,NPAS3" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_200 DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.09E-03 1.00E+00 4.59E-03 4.18E-02 44 170 "ABAT,PCDH19,ARHGAP20,VAT1L,CA4,LGI1,CHGB,CNTN1,CRYM,EBF1,CDHR1,MRVI1,RASL10A,DACH2,FYB1,MEGF10,GALC,DNER,IGSF5,FREM1,GRIA1,PTPRT,FAM19A2,NEGR1,KCNA1,CLEC18A,MN1,NCF2,OXTR,PDE1C,PTPRO,PTX3,ZFHX4,PRR5L,SALL1,SCN8A,SLC14A1,CLSTN2,NEK4,ANO4,TEK,THBS4,HEY1,NETO1" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.09E-03 1.00E+00 4.59E-03 4.18E-02 52 209 "ABAT,PNMA8B,NR0B1,KCNT1,KIF6,LGR5,CDC14B,PPP4R4,PDE8B,ATP2B3,RGS11,SLC16A4,CDH2,AKAP5,GPRASP1,DBI,DBT,SRGAP3,AFF2,ZMAT1,GAB1,RAB30,SHISA6,LRRTM3,KLHL23,KITLG,AFF1,NEXMIF,NFIA,ETFRF1,SEMA5B,PPP3CC,PRKCB,PTPRD,TMEM206,MEG3,PPP1R9A,ST8SIA1,UHRF1BP1L,ARHGAP26,TSPYL2,SMOC1,ST5,FGD4,MTCL1,OBSL1,ZFPM2,DAAM2,FNDC5,TST,NAV2,WNK3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k4 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.10E-03 1.00E+00 4.61E-03 4.20E-02 17 48 "SORCS1,MYOM2,CHN2,AKAP6,FABP7,DNER,RAB40B,GPT2,IFI16,MYH3,MYH7,RGS4,ZFHX4,SLC15A2,SCN3B,HIF3A,TRPS1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.10E-03 1.00E+00 4.61E-03 4.20E-02 17 48 "APOC1,LGR5,CLU,SRGAP3,PLXNC1,FAM198B,AFF2,GPR37,SHISA6,MOV10,TMEM206,SOX6,ST8SIA1,SMOC1,ST5,OBSL1,WNK3" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_100_k3 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.11E-03 1.00E+00 4.63E-03 4.22E-02 16 44 "PCDH19,DOC2A,SLC32A1,GREB1,PSD2,GLDC,PRDM5,HES5,CLEC18A,MID1,NPY,OXTR,PRTG,TMEM100,EMID1,HEY1" Coexpression Atlas GSM538219_500 "B cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 1.11E-03 1.00E+00 4.64E-03 4.23E-02 82 361 "ADD3,SNX30,ZNF608,TXNDC16,BCAR3,FGD2,DGKD,ATP6V0A1,BCL7A,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,PPP1R16B,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,FRY,EGR3,SRPK3,DENND4A,TLR7,PTK2B,CHST15,HVCN1,IGSF5,MALT1,RAB30,DCLK2,EML4,CECR2,RAPGEF4,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,GPR155,MEF2C,CD200,MYO5A,NCF2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,PXK,MARCH1,BEND5,RFX5,LRRK2,SELL,SH3BP2,ST6GAL1,SLC4A3,SLC15A2,LMBRD1,ARHGAP26,SLC37A2,TCF4,CYB561A3,C9orf85,VAV2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100 dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.12E-03 1.00E+00 4.68E-03 4.26E-02 25 82 "NR0B1,ARHGAP20,CALB1,CBLN1,CDH10,HAPLN1,VCAN,DOCK4,DRP2,EDNRA,PLXNC1,GABRA4,FREM1,PCDH11X,GUCY1A1,KLHL23,MATN2,MEIS1,NEFM,PDE1A,PDGFRA,PCDH18,TMEM255A,ADGRL3,ZFPM2" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_100 dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.12E-03 1.00E+00 4.68E-03 4.26E-02 25 82 "AMH,SEMA7A,SHTN1,CADPS,JAM2,CLU,SCRN1,JAKMIP2,DTNA,MRO,PLXNC1,EPS8,ERBB4,PTK2B,TUBB3,FGF13,GATM,GPM6B,PAK3,SERPINE2,RASGEF1B,TMEM206,TNIK,SGK3,WNK3" Coexpression Atlas Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5 FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.13E-03 1.00E+00 4.69E-03 4.27E-02 59 244 "EMILIN3,ACTN2,ADCY2,ARHGAP20,CDK10,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,ANKRD44,CRYM,CSF1R,PLCH2,CCDC3,DLG2,DUSP9,ELN,LRRC17,FCGRT,TRIM16,DLL3,FYB1,TMEM8B,ZNF276,GLRB,WIF1,SYNPO,IL11RA,KLHL23,VWA5A,SRSF12,TCEAL5,NFIA,CNTN3,PLCL1,NXPH1,ACSS3,ZMAT4,ZFHX4,MYH14,DGLUCY,ATXN1,DOCK10,SLC1A2,ZFR2,ADGRL3,PHF24,FAM189A1,TRPS1,TSPAN11,LAMP5,PMEPA1,CADM2,PCDH15" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Overall_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Overall_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.14E-03 1.00E+00 4.74E-03 4.32E-02 46 180 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,CALCRL,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas PCBC_ECTO_100 Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_100 PCBC 1.15E-03 1.00E+00 4.77E-03 4.35E-02 29 100 "CA4,CCK,CDH8,LGI1,COL9A1,CNTNAP2,EMX2,FABP7,B3GAT1,PHYHIPL,ILDR2,CELF3,HES5,LIX1,ZNF385B,OLFM3,CLEC18A,BCO1,KCNK10,PAX6,PRTG,POU3F2,LAMA1,FEZF2,ARX,SOX3,TAC1,CRB2,DPYSL5" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k5_500 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.15E-03 1.00E+00 4.77E-03 4.35E-02 27 91 "SLITRK1,INTS2,TAOK1,LCORL,INSYN2B,RNF182,CALB1,NMT2,CNR1,RBM39,TENM4,DOCK4,DRP2,ELAVL2,SCML2,GABRA4,KCND2,KITLG,SERPINI1,PCMTD2,FNIP1,SYBU,CPEB4,LARP4,SYNE2,ACTR6,EMX2OS" Coexpression Atlas GSM854326_100 "Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3" "Immgen.org, GSE15907" 1.15E-03 1.00E+00 4.77E-03 4.35E-02 27 91 "C1QC,ADGRG1,LY86,CRYBB1,CSF1R,CSF3R,CX3CR1,SIRPA,TLR7,FCGR1A,HPGDS,GLUL,GPR34,ITGAM,P2RY13,SERPINE2,PMP22,RAB3IL1,GAL3ST4,TMEM100,SALL1,SLC2A5,SLC11A1,TF,P2RY12,AGMO,PLD4" Coexpression Atlas GSM854294_500 "Myeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.16E-03 1.00E+00 4.81E-03 4.38E-02 94 424 "TMCC3,ALCAM,ABCD2,GAS7,APP,SHTN1,CASK,ATP1A3,ADAM15,ST3GAL5,C1QC,CD86,CD81,SOCS6,CHN2,B4GALT6,LY86,GDA,CSF1R,CSF2RA,ATRNL1,GALNT9,CST3,PLXNA4,SDC3,CTNND1,CX3CR1,CYBB,HDAC9,MYADM,KIAA0513,DAPK1,DBI,SIRPA,ZEB2,DMPK,FAM78B,EDNRB,EPS8,IGSF6,ETV1,SIRPB1,F5,FABP7,FCGR3A,FCGRT,OLFM1,FGFR1,FGR,FOLR2,AK8,TPPP3,GATM,GFRA2,SLC2A6,ATG4C,IRAK3,LRRC25,DOCK7,ITGAM,LAMP2,LIFR,MITF,MSR1,NCF2,NUCB2,P2RY1,CDK14,PLTP,PMP22,PILRA,DRAM2,PTAFR,PID1,C1orf54,PRR5L,ACER3,MRAS,CCDC88A,SLC11A1,FGD4,PLCB1,KIAA0930,AHCYL2,TF,TIAM1,TLR4,TRPS1,TUBB2A,LAT2,SLC13A3,AGMO,EVI5,PLD4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k3 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.20E-03 1.00E+00 4.99E-03 4.55E-02 32 114 "ASTN1,RUNX1T1,CCNH,AP4M1,HAPLN1,HP1BP3,EFS,EFEMP1,SUCO,DPYSL4,NSG2,TPPP3,CHL1,GRIK1,MEIS1,SCAMP5,NEFM,NTRK2,PCDH8,PCDH18,PRRX1,TNPO2,RALGDS,FAM102A,SLC4A3,LRRC4,MAPK8IP3,ITGB3BP,VSNL1,LYPD6,RGMA,STOX2" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k2_200 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.21E-03 1.00E+00 4.99E-03 4.55E-02 21 65 "LCORL,BACH1,RUNX1T1,CHM,SLIT2,RBM39,FGFR1OP2,TCAF1,EDNRA,EIF4G1,EMX2,SMC2,LPAR4,CHIC1,MEIS2,NASP,TMEM255A,TMLHE,SCMH1,CBX5,SSBP2" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_100 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.21E-03 1.00E+00 5.02E-03 4.57E-02 24 78 "AMPH,VAT1L,CACNA2D1,CACNB4,RBM39,CRYM,DYNC1I1,ELAVL4,CDHR1,EYA1,FGF1,SGIP1,DACH2,GFRA1,FAM19A2,FAM107A,HAS2,FRMD3,NELL1,NXPH1,SALL1,ANKRD6,SLC1A3,ERCC6L2" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000_k5 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.21E-03 1.00E+00 5.02E-03 4.57E-02 66 280 "ACADM,GRAMD1B,OSBPL6,ASPA,SLC4A4,CFLAR,CA4,CA12,ISPD,MAP7,SLC16A4,CLTC,OSBPL3,GUCD1,SMG7,RABGAP1L,SGK2,PAN3,PIPOX,FGFR3,ATP13A4,FOLR2,FUT9,PHYHIPL,ILDR2,GALC,GHR,GK,CNDP1,TMEM25,HPS5,NCOA7,C2orf80,MYO6,MYO9A,IGSF11,ENPP2,RETREG1,DRAM2,POU6F1,RANBP3L,PTH1R,ELOVL2,SH3TC2,SLC6A15,LRRK2,LGR4,RYR3,HOGA1,IL17RB,KIF21A,PPP1R9A,SLC15A2,SPATA7,SPP1,RBM26,PBLD,NEK4,SEMA4A,FAM208A,SATB2,VWCE,LRRC8A,TRPS1,VLDLR,ADAMTS9" Coexpression Atlas Lungmap Mouse Lung PND1 Endothelial Subtype Vascular Endothelial-D Lungmap Mouse Lung PND1 Endothelial Subtype Vascular Endothelial-D Lungmap CCHMC 1.23E-03 1.00E+00 5.10E-03 4.65E-02 53 215 "SYN3,FMNL2,CCDC85A,ADRB2,SEMA7A,PRX,PDE8B,ATP2B1,FOXK1,CA4,KALRN,ABCG1,DPYSL2,FAM78B,EDN1,EDNRB,CEP85L,ATP8A1,SORBS1,TPPP3,INPP5K,PCDH17,LYVE1,STARD3,GNAO1,FAM107A,TOX2,MAPT,KITLG,CD200,PDE2A,KANSL1,SNRK,RAB3A,TMEM100,CLIP1,SEC14L1,BTBD3,SLC12A2,LMBRD1,PHLDB1,SLC35G2,PCDHA2,TGFBR3,MTMR14,TIE1,ASXL3,TPM3,DCBLD1,RBFOX3,MKRN3,ZBTB16,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 1.24E-03 1.00E+00 5.12E-03 4.67E-02 54 220 "NDRG2,AGT,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,RASL12,FGFR3,FHL1,UBE2E3,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NAP1L1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SCHIP1,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,ADAMTS17,TACC1,PDLIM2,TGFBR3,HHIP,VLDLR" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.25E-03 1.00E+00 5.16E-03 4.70E-02 12 29 "ASPHD1,CHGA,ATL1,TUBB4A,PCSK1N,GNG3,CELF3,SCRG1,PACRG,PCBP3,SLC10A4,TMEFF2" Coexpression Atlas GSM538255_500 "Myeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 1.25E-03 1.00E+00 5.16E-03 4.71E-02 94 425 "CPNE2,FMNL2,ADCY6,ADORA3,RNF150,ADRB2,ALCAM,SEMA7A,FGD2,APP,SHTN1,TMEFF1,ARHGAP5,ADAM23,ST3GAL5,BTK,CACNA1E,SPAG9,CD86,SCARB1,CD81,ARHGAP22,LY86,FAM149A,SLC4A8,ZNF385A,CDC42BPB,CSF2RA,OSBPL3,CST3,SDC3,CTNND1,DAPK1,DBN1,SRGAP3,CDON,ARRDC4,PLXNC1,RASA4,PLEKHO1,EPS8,FCGRT,OLFM1,FGR,ZMYND15,GALC,NEK6,GATM,RAB30,MAP4K5,HPS5,IRF8,IFI16,LRRC25,DOCK7,JAK2,KIT,ASPRV1,ADAM11,ADAM22,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,PFKFB3,CDK14,RASGEF1B,SLC22A23,MARCH1,PID1,C1orf54,ROGDI,SNX22,PRR5L,LRRK2,KCNIP3,SEMA6D,ARHGEF40,CCDC88A,SLC11A1,ITPRID2,SULF2,SEPT3,CYB561A3,TF,SLC44A1,TIAM1,DDHD1,TRPM2,CADM1,SIGLEC10,PLD4,PIANP" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_200 dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.27E-03 1.00E+00 5.22E-03 4.76E-02 45 176 "NR0B1,PPP4R4,DDX3Y,TMEM108,CALB1,CBLN1,CDH10,DCLK1,HAPLN1,VCAN,PLXNA4,DOCK4,SCRN1,DCT,DRP2,EDNRA,PLXNC1,EMX2,F3,FABP7,FLNC,GABRA4,FREM1,PPARGC1A,PCDH11X,GPR37,GUCY1A1,KCND2,KLHL23,MATN2,MEIS1,NEFM,PDGFRA,SERPINI1,PCDH18,RASGEF1B,ROBO2,PALLD,UHRF1BP1L,SMOC1,ADGRL3,ZFPM2,ACTR6,WNK3,DPF3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K5 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 1.27E-03 1.00E+00 5.24E-03 4.78E-02 20 61 "INA,FAM169A,RRAGB,REEP2,TUBB4A,SALL3,TOX3,CECR2,HSP90AA1,PRTG,IRX1,SALL1,PBLD,AJAP1,MTCL1,WWC1,WASHC4,CADM1,ZIC2,ZBTB16" Coexpression Atlas PCBC_DE_fibroblast_500 Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_500 PCBC 1.29E-03 1.00E+00 5.31E-03 4.84E-02 107 494 "KCNH8,ADCY2,SORCS1,ERMN,NLGN4X,NR0B1,SEMA6A,PCDH10,UNC79,PDZD4,APOC1,LGR5,SLC7A14,ARSE,KIF1A,FGF17,BTK,CCKBR,CDH8,CHGA,IGLON5,COL9A1,GAL3ST1,TENM4,NCAN,RIMS4,CNTNAP2,PLCXD3,CALN1,EFNA2,ELAVL4,TMEM74,ADGRV1,FABP7,C1orf61,B3GAT1,MEGF10,HRASLS5,GABRA5,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,TMEM179,HAS2,IGFBPL1,HP,CELF5,TUBB2B,KCND2,KCNF1,CLVS2,KCNQ2,KIF5C,KIT,MATN3,MOBP,SCG3,DDX25,NODAL,SEMA5B,A2ML1,JAKMIP1,PACSIN1,PPP2R2C,LAMA1,ELOVL2,STK32A,SLC25A48,FAM184A,RET,PRIMA1,HUNK,RXRG,SALL1,TMEM200C,SOX3,LHFPL4,MCF2L2,ZFR2,TMEM150C,SYT4,TAC3,KLHL4,LEFTY2,GALNT17,ENHO,TMOD1,PIK3R5,SEZ6L,TRPM2,RPRM,RBFOX3,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,ANKS1B,CADM2,GAL3ST3,JPH3" Coexpression Atlas PCBC_MESO-5_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_500 PCBC 1.29E-03 1.00E+00 5.31E-03 4.84E-02 107 494 "KCNH8,CSMD3,SORCS1,ADORA1,NR0B1,UNC79,PDZD4,DPP10,APOC1,LGR5,ARSE,KIF1A,FGF17,BMP7,BTK,C5,MYRF,CCK,CCKBR,USP2,CDH8,PLEKHB1,IGLON5,COL9A1,COL9A2,COL9A3,GAL3ST1,NRG2,CNTNAP2,PLCXD3,SV2B,DSCAM,FAM78B,USH1C,ELAVL4,ERBB4,RASL12,ADGRV1,C1orf61,B3GAT1,MEGF10,HRASLS5,GABRB3,GATM,GNAL,GPM6A,TMEM121B,GRIK3,PTPN5,FAM222A,HAS2,NXPH2,IGFBPL1,SHISA6,KCNF1,CLVS2,KCNJ3,KCNQ2,KIT,MATN3,SCG3,NODAL,HCN1,IGSF11,PCDH8,SEMA5B,A2ML1,JAKMIP1,PACSIN1,RELN,LAMA1,ELOVL2,STK32A,SLC25A48,FAM184A,KHDRBS2,PRIMA1,MRAP2,RXRG,SALL1,TMEM200C,SOX10,MCF2L2,SSTR2,AJAP1,ZFR2,TMEM150C,FAM189A1,LEFTY2,GALNT17,PIK3R5,SEZ6L,TRPM2,CA14,RPRM,RBFOX3,ETNPPL,KCNK12,ZIC3,KCNT2,FMN2,ANKS1B,CADM2,SHD,GAL3ST3,FAM198A,JPH3" Coexpression Atlas gudmap_developingGonad_P2_epididymis_200 DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.32E-03 1.00E+00 5.40E-03 4.92E-02 41 157 "ADCY8,PNMA8B,C1QTNF3,ARHGAP20,PKP4,ATP1A2,ATP2B1,BACH1,VSTM2A,RGN,DCLK1,CHM,CP,RBM39,MFAP3L,ZC3H11A,CHRDL1,EDNRA,EIF4G1,LRRC17,GABRB1,GAD1,GLUL,CNDP1,LPAR4,MAOB,CHIC1,MEIS2,NFIX,PENK,NALCN,VEPH1,TMLHE,MRAP2,MEG3,ARX,SYNE2,PCDHB9,HHIP,CBX5,SSBP2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.32E-03 1.00E+00 5.40E-03 4.92E-02 41 157 "USP31,DPP10,ANK2,CACNA1B,CNR1,HAPLN1,EDRF1,BRINP1,GRIN3A,EDIL3,SEMA3D,ETV1,CORO2B,FGF13,DACH2,GAB1,GABRA1,SYT17,GFRA1,PPARGC1A,FRMD5,SAMD5,HMGCLL1,MAGEL2,C12orf49,CCDC112,SATB1,CXXC4,CMTR2,TNIK,KIF1B,CLASP2,TROVE2,EPB41L3,NEK4,ITGB3BP,SGK3,RPRM,SLAIN1,NUP214,SOCS4" Coexpression Atlas GSM538230_500 "B cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5+ CD45R+, Peritoneal Cavity, avg-1" "Immgen.org, GSE15907" 1.32E-03 1.00E+00 5.40E-03 4.92E-02 76 332 "ADORA2A,SNX30,TXNDC16,BCAR3,SEMA7A,FGD2,GAS7,DGKD,TMEFF1,NRP2,BTK,CACNA1I,CACNA1E,CAMK2D,CD86,CD38,LY86,CNN3,CDC42BPB,ATRNL1,SIPA1L1,RUBCN,CYBB,MYADM,SIRPA,GUCD1,EBF1,RASGRP1,FRY,PLXNC1,KCTD3,SRPK3,DENND4A,TLR7,AK8,TPPP3,ACSS1,MALT1,RAB30,CECR2,TPPP,ADAMTS6,MAP4K5,IRAK3,TUBB2B,ITGAM,LIFR,MEF2C,MYO5A,NAP1L1,NUCB2,PPP3CC,DIRAS2,MARCH1,BEND5,LRRK2,RASA3,ST6GAL1,SLC20A2,LMBRD1,SOX5,STAC2,SLC37A2,TCF4,PSD3,CYB561A3,TLR4,TPD52,C9orf85,TUBB2A,LAT2,EVI5,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas ratio_SC_vs_ECTO_500_K2 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 1.33E-03 1.00E+00 5.46E-03 4.98E-02 75 327 "ADCY2,PTCHD1,PDZD4,CALB1,SYT6,CBS,DCLK1,CHGA,RAB3C,CRYBB1,GALNT9,RIMS4,KCTD8,BRINP1,NTM,RABGAP1L,CALN1,ST8SIA3,LINC00599,SEZ6,PIPOX,PPP1R1B,OLFM1,HPCAL4,FLT1,MEGF11,MEGF10,HRASLS5,GABRA5,GABRB3,JPH4,ATP8A2,ADAMTS8,LINGO1,WIF1,C1orf94,HRH3,RIPPLY2,LRRTM3,KCNN2,KCNQ2,CAMK2N2,FGFBP3,C2orf80,CPNE9,SCG3,FXYD7,NOS1,HCN1,ZDHHC22,GDAP1L1,CAMKV,EPB41L4B,TMEM145,SLC25A48,RET,RIT2,RORB,MRAP2,RIMKLA,BCAN,SEPHS1,TMEM132D,OGDHL,SNCB,HECW1,SYN1,ARC,TAC3,KLHL4,TMEM151B,TEX15,IL34,ZIC3,NETO1" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.35E-03 1.00E+00 5.50E-03 5.02E-02 65 276 "EMILIN3,ACTN2,ADCY2,SRPX,ARHGAP20,CDK10,ATP1A3,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,NIPBL,ABI3BP,ANKRD44,CSF1R,PLCH2,CCDC3,DLG2,RASA4,ELN,EPB41L1,LRRC17,FCGRT,TRIM16,FYB1,ARPP21,TMEM8B,ZNF276,GLRB,WIF1,SYNPO,IL11RA,VWA5A,SRSF12,TCEAL5,NFIA,NFIX,CNTN3,PLCL1,NXPH1,ACSS3,RBBP8,ZMAT4,DUSP15,ZFHX4,MYH14,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC1A2,SLC6A9,ZFR2,ADGRL3,PHF24,FAM189A1,TSPAN11,PMEPA1,CADM2,PCDH15" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_200 kidney_P0_CapMes_Crym_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.35E-03 1.00E+00 5.50E-03 5.02E-02 34 124 "ALCAM,AMPH,IL33,CACNA2D1,CNTFR,CRYM,SNCAIP,VCAN,PHF19,SPOCK2,SNAP91,ELAVL4,ETV1,EYA1,FGFR1,IGSF5,GFRA1,FREM1,HAS2,NEGR1,MEIS2,NCAM1,NELL1,CNTN3,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1,SLC1A3,CUX2,TPM2,CADM1" Coexpression Atlas GSM605859_500 "Myeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.35E-03 1.00E+00 5.53E-03 5.04E-02 94 426 "TMCC3,ALCAM,ABCD2,FGD2,GAS7,APP,SHTN1,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,C1QC,CD38,SOCS6,B4GALT6,LY86,GDA,CSF1R,CSF2RA,CSF3R,ATRNL1,GALNT9,CST3,PLXNA4,SDC3,CTNND1,CX3CR1,CYBB,MYADM,KIAA0513,DGKG,DAPK1,DBI,SIRPA,ZEB2,ARRDC4,FAM78B,EDNRB,EPS8,IGSF6,TLR7,SIRPB1,FCGR3A,FCGRT,OLFM1,FGFR1,FGR,AK8,TPPP3,GATM,SLC2A6,ATG4C,IRAK3,LRRC25,DOCK7,IL6R,ITGAM,LAMP2,LIFR,MITF,MSR1,NCF2,NUCB2,P2RY1,PFKFB4,CDK14,PLTP,PMP22,PILRA,DRAM2,PTAFR,PID1,C1orf54,PRR5L,ACER3,MRAS,CCDC88A,SLC11A1,ELMO2,SULF2,FGD4,KIAA0930,TF,TIAM1,TLR4,TPD52,TRPS1,TUBB2A,LAT2,SLC13A3,AGMO,EVI5,PLD4" Coexpression Atlas gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4 DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.37E-03 1.00E+00 5.59E-03 5.10E-02 62 261 "RALGAPA1,AP2A2,OGT,ANK3,APC,EPB41L5,DGKD,CASK,BMP7,SCAPER,CANX,LRRFIP1,CLCN3,COL4A5,RBM39,VCAN,DDX46,HIPK3,SEMA3D,EIF5,EIF1,VPS13B,KIAA1109,SUCO,ANKFY1,DKK3,RAPGEF6,IQGAP2,PPARGC1A,GRB10,ICA1,KIF2A,LIFR,CHIC1,MKLN1,PIK3C2A,STRN3,KANSL1,PKN2,GON4L,DPF2,REV3L,SFPQ,PPP1R9A,RUFY2,NAPB,MYCBP2,STX1A,PRRC2C,DNMBP,CAMSAP2,WWC1,MGRN1,OBSL1,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,GOPC,DOCK8,NUP214" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_1000_K5 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5 FaceBase_RNAseq 1.38E-03 1.00E+00 5.61E-03 5.11E-02 27 92 "APBB1,MPDZ,BMPR1B,CDC25B,SRSF11,LHX2,SIPA1L1,ST18,RASSF2,CTIF,DLX1,BRPF3,GPM6A,GRIK2,TOX2,PAXBP1,NNAT,GAL3ST4,ZFP2,CASC3,SLC12A2,STAU1,ZC3H4,HEY1,BHLHB9,TP53BP1,GAN" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_k4_200 kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.39E-03 1.00E+00 5.67E-03 5.17E-02 18 53 "AMPH,CACNA2D1,CACNB4,CNTFR,CRYM,SNCAIP,PHF19,SNAP91,ELAVL4,ETV1,EYA1,HAS2,NEGR1,MEIS2,FAT3,MDGA2,SLC1A3,TPM2" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_500_k3 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.41E-03 1.00E+00 5.75E-03 5.24E-02 32 115 "TKTL1,LCORL,LGR5,PDE8B,ASPA,DDX3Y,INSYN2B,SYNJ1,CALB1,CNR1,MAGI2,DRP2,RASGRP1,KIAA1109,GRK4,KCND2,KITLG,NEXMIF,GLIPR1L2,SERPINI1,PLP1,PRCD,FNIP1,TNFRSF19,SYBU,CPEB4,SLC37A2,ZNF711,ZNF23,EMX2OS,REEP1,KLHDC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200_k4 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.43E-03 1.00E+00 5.82E-03 5.31E-02 14 37 "RNF182,HAPLN1,BRINP1,FOXF2,MEGF10,GABRA4,IFI16,KCNK2,RSPO2,NAP1L2,NDP,DDR2,ZFHX4,EPB41L3" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_1000 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.43E-03 1.00E+00 5.82E-03 5.31E-02 14 37 "GRAMD1B,APOC1,DDX3Y,SCARB1,FADS2,MICAL2,VCAN,RIPOR2,FABP7,IQGAP2,LAMA1,PTCH1,ACSBG1,VSNL1" Coexpression Atlas gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000 dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.44E-03 1.00E+00 5.87E-03 5.35E-02 167 820 "TKTL1,AXIN2,BRAP,CDC7,USP31,ESYT2,MTA3,HACE1,HFM1,FAM135A,USP28,PARG,DGKD,ALS2,APOC2,USP37,SHTN1,CPNE5,PPP4R4,MADD,PLA2G4C,CAPRIN2,DDX3Y,ATM,CCDC181,ZNF583,RNF182,ADAM23,BARD1,BLM,NAE1,SCAPER,PRMT9,OSGIN2,RUNX1T1,MTMR7,AIFM1,LRBA,LONRF2,KMT2C,ZFYVE9,PLAA,NMT2,C4orf33,CHD1L,FAM169A,DZIP3,CFAP61,RIMS2,EDRF1,PHF19,FBXL5,FBXO25,RABGAP1L,NR1D2,CPEB2,CASP8AP2,DUSP9,DNAJB6,ATL1,KCTD3,ELAVL2,PLEKHA1,PCOLCE2,DENND4A,RRAGB,SCML2,MED12L,KIAA1109,FGF13,PRKAG2,C2orf88,EFCAB2,CINP,ATP6V1H,PHYHIPL,WASF3,TUBGCP4,GLDC,DBF4,MAP7D2,DCLK2,TDRKH,CECR2,GRK4,COQ10A,MAEL,ARHGAP19,DDX19B,HSF2,HSP90AA1,KIT,SYT9,ADAM22,DDX25,MTR,MYO9A,NEK1,NOVA1,TBC1D25,PRTG,PDE3B,PENK,ANLN,GPSM2,PMS2,C19orf57,PPP2R5C,PPP3CC,PPP5C,CEP41,PRKCZ,PRPSAP2,BCAS3,UHRF1BP1,EML5,ZCWPW1,RBBP8,CARF,CCDC25,FBXW7,MCMBP,ADAL,ACER3,STX1B,FNIP1,KIF27,HSPA4L,SH3BGR,MAGI3,CNKSR2,CCDC92,TET1,ZNF667,GKAP1,DOP1A,SOX2,TEX2,BEX1,EPB41L3,LARP4,ZSCAN29,VPS13A,ANKRD12,DDHD2,TAF6,DMXL2,SATB2,TEX15,SIRT1,DDHD1,ERCC6L2,RUNDC3B,TRPC1,UGT8,SLAIN1,PORCN,ZIC3,SLC30A4,LMAN2L,SNX27,WNK3,PHTF2,ACTR3B,RNF170,AAAS,NETO2" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K0 facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K0 Gudmap RNAseq 1.46E-03 1.00E+00 5.91E-03 5.38E-02 46 182 "ABAT,C1QTNF1,APP,MYOM1,NRP2,UBE2L6,NRXN3,ARHGEF6,SDC3,DGKB,RCAN2,TLR7,RASL12,CHST15,FCGRT,TPPP3,GDF9,LOXL3,GRM7,GUCY1A1,SHC3,CCDC80,MX1,NRGN,P2RX7,PDE3A,PDGFRA,SERPINE2,PIK3CD,FXYD1,PTN,ZMAT4,RGS4,EMID1,DOCK10,ZCCHC24,NKAIN2,PDLIM2,TNS2,GPRIN3,GALNT17,ENHO,DAAM2,TNS1,IL34,SSPN" Coexpression Atlas seminal vesicle seminal vesicle Human Protein Atlas 1.47E-03 1.00E+00 5.97E-03 5.44E-02 36 134 "PTCHD1,PCDH10,CDH8,CPNE6,HS3ST5,CHRDL1,EDNRA,TMEM35A,EMX2,RASL12,JPH4,MFSD2A,PLD5,SYT9,MYH3,NEFM,PDZRN4,FAT3,NWD1,CRTAC1,ZFHX4,RPE65,NLGN4Y,FHOD3,UNC5B,STAC2,ARC,ANO4,ACSL6,RASD2,SYNPO2,CA14,VIPR2,RBFOX3,PRDM8,CBLN2" Coexpression Atlas gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k1_1000 dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.47E-03 1.00E+00 5.98E-03 5.45E-02 47 187 "SPARCL1,SEMA6A,LCORL,ARRB1,DOCK11,BACH1,SPAG9,LDB2,CNN3,ZNF521,CREB5,DBN1,ARMCX4,EDIL3,YAF2,MBNL2,LPAR6,PLEKHO1,STX2,RCSD1,DLC1,CHST15,UFM1,FYN,NEK6,ATF7,ZDHHC15,IGF1,ITPKB,MEST,MYO6,OPHN1,PALM,PDE4D,GNG2,ROBO1,SEMA6D,SMTN,PEG10,ZNF423,RGL1,ARHGEF9,TCF4,ZEB1,ZNF711,PMEPA1,STOX2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.48E-03 1.00E+00 6.00E-03 5.47E-02 65 277 "KDM5D,USP31,SORCS2,ALCAM,DPP10,ANK3,NOL4,CACNA1B,CERS5,USP6NL,GAPVD1,SPOCK2,GRIN3A,CALN1,RCAN1,EDN1,FEM1B,AASS,LPAR6,FGF13,DACH2,MEGF11,GAB1,GABRA1,GFRA1,GGT5,PPARGC1A,GPD2,SOX21,FRMD5,AGFG1,ASPRV1,MARK1,SYT9,ODF2,OXTR,SMIM7,HMGCLL1,MAPK10,GRAMD1C,DIRAS2,RBBP8,ARMH4,HUNK,SATB1,SOX6,KIF16B,PEX26,CXXC4,KIF13A,PDZRN3,SOX2,ARC,TCF7L2,HIF3A,ZMAT3,TIAM1,CHST5,SGK3,CADM1,SLAIN1,SF1,FZD3,PHTF2,RNF146" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_500 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.50E-03 1.00E+00 6.05E-03 5.51E-02 28 97 "KDM5D,SEMA7A,GAS7,CADPS,DDX3Y,ALDH7A1,DST,ST3GAL5,ADGRG1,SCRN1,DTNB,MRO,PLXNC1,EPS8,PTK2B,BRPF3,GATM,KCNH1,MSI1,PAK3,SERPINE2,RASGEF1B,ROBO1,RPS6KA2,MRAS,DOCK10,SPP1,ADAMTS9" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRglf_Top_40_Genes GSE76381_ESMoleculeCountsPMLog2 1.50E-03 1.00E+00 6.05E-03 5.52E-02 21 66 "CDO1,CLU,COL4A5,CNTNAP2,ZIC4,C1orf61,GAP43,DNER,IGFBPL1,OLFM3,LIFR,RSPO2,NFIA,NTRK2,PDE1A,PDE4D,ZMAT4,RFX4,WLS,ZIC1,ZIC3" Coexpression Atlas PP_RBC_2500_K3 PP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3 PCBC 1.50E-03 1.00E+00 6.05E-03 5.52E-02 41 158 "DPY19L2P4,DDO,SPTBN4,AZGP1,GPR146,LDHD,LONRF2,FCGR3A,KBTBD12,HRASLS5,GPM6A,GPR22,FAM95B1,NFIX,PDE4A,PMP22,RAB3IL1,ROGDI,RNASE1,TNFRSF19,SMPD3,ASAP3,SLC11A1,OGDHL,ZNF415,SCN3B,DOK5,IDI2-AS1,KLHL7,PCDHGC5,PCDHGB6,PCDHGB2,PCDHGA6,PCDHGA3,PCDHGA2,PCDHB15,PCDHB10,PCDHB9,PCDHB3,TMOD1,PDIA2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.50E-03 1.00E+00 6.05E-03 5.52E-02 41 158 "PCDH10,SYT13,INSYN2B,DST,CH25H,RUNX1T1,CBLN1,DCLK1,CRLF1,SCRN1,NTM,DLX1,TMEM132C,FOXF2,SGIP1,DKK3,MEGF10,GABRA4,CHL1,GABRB1,GFRA2,GNG4,GRIA2,WIF1,MYH3,PAH,PRRX1,ZFHX4,PRR5L,SALL1,SLC15A2,LIMCH1,SOX2,SOX11,EPB41L3,TAC1,UNC5D,SATB2,SYNPO2,WNT7A,KCNAB1" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k4 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.50E-03 1.00E+00 6.05E-03 5.52E-02 41 158 "ADORA1,ALAD,AMPH,EPB41L5,USP37,LGR5,DYNLL1,CLU,RBM39,KIAA0040,GREB1,HSD17B14,FABP7,ST3GAL6,FGFR3,FOXO3,KHDRBS3,SALL3,MTHFD2,IGSF5,AP4S1,HES5,CLEC18A,TM6SF1,NPY,OXTR,PALM,PTPN13,TMEM100,EMID1,DOCK10,EFHD1,SLIT1,SMARCA4,EMC1,CAMTA1,TRIM2,HEY1,TPD52,ZNF24,SPIRE1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k3 DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.50E-03 1.00E+00 6.07E-03 5.53E-02 49 197 "NCKAP5,EPB41L5,AQP4,PROM1,WASF1,CALB1,LRBA,CDO1,CBARP,FAM149A,IPCEF1,ERC2,CTH,EMX2,SYNCRIP,EFCAB2,PPARGC1A,GK,TCERG1,CCDC184,SCIN,C2orf80,AQP11,MYBPC1,CNOT4,CLDN11,PCDH8,PDE1C,PLXNB1,PTPRD,PTX3,RBBP8,PRR5L,EMID1,LGR4,SCN8A,LINC00461,HKDC1,SLC15A2,BEX1,PCDHB9,CHST5,UGT8,LYPD6,MAP3K12,VPS35L,PHTF2,NETO2,SOCS4" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype Pericyte-A Lungmap Mouse Lung PND3 MatrixFB Subtype Pericyte-A Lungmap CCHMC 1.52E-03 1.00E+00 6.13E-03 5.58E-02 61 257 "SPARCL1,MAP4K3,APP,CD81,CDH2,CHN1,NRXN1,CNN3,MAGED1,ACBD5,VCAN,ZEB2,EBF1,EDNRA,RASGRP2,RASL12,TUBA1B,SGIP1,NPTN,TPPP3,DKK3,GAP43,HIGD1B,FERMT2,TUBA1C,GUCY1A1,GUCY1B1,KCNK3,KTN1,LIMS1,MAPT,MEST,NFIA,NFIX,PIK3R1,FXYD1,PCDH18,SEPT4,SH3KBP1,NKAIN4,PRKACB,SNRK,RGS4,TTLL7,PRR5L,EMID1,PEAR1,BTBD3,PDZD2,SOX5,CLSTN2,SSTR2,TCF4,PCDHGA9,SLC35G2,THRA,TNS1,TPM1,TPM4,CADM1,TUBA1A" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.56E-03 1.00E+00 6.29E-03 5.73E-02 34 125 "SPARCL1,ALCAM,ARHGAP20,CACNA1G,CBLN1,REPS2,SLIT2,HAPLN1,MICAL2,VCAN,ARMCX2,EDNRA,EGFR,LRRC17,ST6GALNAC3,NEK6,GFRA2,FREM1,GHR,GLI2,GUCY1A1,LAYN,PCDH9,PDGFRA,FAT3,LAMA1,TMEM255A,ROBO2,ARMH4,NTNG1,NPAS3,SULF2,VSNL1,ZNF711" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K4 FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.58E-03 1.00E+00 6.35E-03 5.78E-02 81 360 "ACTN2,OSBPL1A,TBC1D14,KIAA1324,GAS7,CPNE5,ARRB2,ASPH,ATP1A3,RIPK1,ZNF599,TRIM41,ARHGEF1,FAM149A,SUMF2,CREM,CRY2,OSBPL3,PLCH2,PITPNC1,EDNRA,HIPK3,NCALD,CDKL3,CORO2B,EFEMP1,ST3GAL6,PPP1R1B,POLK,APOPT1,UFM1,TPK1,DLL3,TMEM8B,RAPGEF4,ADAMTS6,GUCY1B1,SMAP1,IGF1,DOCK7,IL11RA,KCNJ5,KIT,HECTD2,MBNL1,BCO1,RSPO2,NFE2L2,SMIM11A,OPHN1,ETFRF1,PCSK5,ENPP2,PCDH18,DIRAS2,MASP1,CYBC1,GDPD2,TMEM260,STRC,REV3L,FAM161B,KCNIP3,SEMA6D,SH3BP2,MYO18A,SLC1A2,SLCO1A2,NAXD,MBD5,SPATA7,C11orf87,ERBIN,LEFTY2,HHIP,TMOD1,TNS1,TSC1,LRTM2,EVI5,PRRT4" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.59E-03 1.00E+00 6.41E-03 5.84E-02 23 75 "PDE8B,REPS2,MAGI2,NRN1,NSG1,GABRB1,TCEAL6,IGF1,PLD5,MTR,LAYN,NEXMIF,NPR2,PDE1A,GDPD2,SEMA6D,PRCD,TNFRSF19,STUM,NPAS3,TEX15,DAAM2,LYPD6" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_200 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.60E-03 1.00E+00 6.43E-03 5.86E-02 11 26 "SPARCL1,EDNRA,LRRC17,FABP7,FREM1,GUCY1A1,PCDH9,PDGFRA,TMEM255A,ROBO2,VSNL1" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_100 kidney_P2_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.64E-03 1.00E+00 6.56E-03 5.98E-02 25 84 "AMPH,IL33,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,ELAVL4,ETV1,EYA1,ST3GAL6,FGFR1,IGSF5,GFRA1,HAS2,NCAM1,NELL1,CNTN3,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1,CADM1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial Top 200 Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial Top 200 LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.64E-03 1.00E+00 6.56E-03 5.98E-02 92 418 "CCDC85A,ZNF608,SNX32,ADGRF5,SPARCL1,SEMA6A,CDC42BPA,PKP4,DGKZ,PRX,NUMB,ADAM15,MTMR2,LDB2,SCARB1,CD38,CNOT8,JAM2,ABCG2,CNN3,CDC42BPB,HAPLN1,ABCG1,PPP1R16B,CTNND1,GIT2,MYEF2,EDIL3,EDNRB,KLHL5,LPAR6,SORBS3,PLEKHA1,CALCRL,HSPA12B,ARMCX1,FAM198B,ST3GAL6,FLT1,TRIM16,NCKAP1,PCDH17,LYVE1,LPAR4,STMN2,GRB10,GSTM5,MAP4K5,ICA1,KIT,STMN1,LMO2,MEF2C,MEIS2,MEST,KITLG,AFDN,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,RIPOR1,C1orf54,RDX,RGS12,TMEM100,RPS6KA2,SEMA6D,SCN7A,SGK1,BTBD3,SCN3B,SOX11,MYCBP2,SPTAN1,THSD1,ST5,NSFL1C,TCF4,ZEB1,DOCK9,TEK,TIE1,HEY1,TJP1,LRRC8A,TMPO,TUBB2A,NPDC1,TUBA1A" Coexpression Atlas Facebase_RNAseq_e10.5_Maxillary Arch_500_K1 FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 1.64E-03 1.00E+00 6.56E-03 5.98E-02 27 93 "ACTN2,APOC2,ZFYVE28,PDE8B,ATP1A3,BARD1,ZNF599,IL33,KCNAB3,VAX2,CRYBB1,PLCH2,PTK2B,ZMYND15,ABLIM2,ARPP21,GRK4,SCIN,ZNF385B,GPR155,BCO1,PDE4D,STRC,DUSP15,SLC1A2,TMOD1,DNAH10" Coexpression Atlas gudmap_developingGonad_e16.5_ovary_1000_k3 DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.64E-03 1.00E+00 6.56E-03 5.98E-02 27 93 "CACNB2,RBM39,TENM4,GSDME,SNAP91,G3BP2,DNAJB6,PLXNC1,ELAVL2,ILDR2,GATM,GGT5,MAP7D2,KIF3A,SHISA6,SYTL4,NEXMIF,ABCB1,PLP1,SATB1,CPEB3,SLC12A2,MYT1L,SYNE2,ANKRD12,CAMTA1,DMXL2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k2 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.64E-03 1.00E+00 6.57E-03 5.98E-02 9 19 "ELAVL2,GFRA2,MATN2,CLDN11,PRRX1,LGI2,TROVE2,ZFPM2,HHIP" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200 dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.67E-03 1.00E+00 6.67E-03 6.08E-02 40 154 "ALCAM,ARHGAP20,TMEM108,MYRF,RUNX1T1,CBLN1,CLU,MICAL2,VCAN,EDNRA,MRO,PLXNC1,EYA1,PTK2B,FLNC,AFF2,GABRA4,GATM,FREM1,PPARGC1A,GLI2,GRIA4,GUCY1A1,KLHL23,MAP2,PAK3,PDGFRA,SERPINE2,PCDH18,PLTP,FAT3,PTCH1,TMEM255A,ROBO2,SULF2,ADGRL3,ZFPM2,HHIP,VSNL1,STOX2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_200 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.69E-03 1.00E+00 6.73E-03 6.13E-02 19 58 "NR0B1,CALB1,PLXNA4,DOCK4,DCT,DRP2,EMX2,GABRA4,PCDH11X,KCND2,KLHL23,CCDC80,PDE1A,LGR4,UHRF1BP1L,SMOC1,ADGRL3,ZFPM2,ACTR6" Coexpression Atlas Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4 FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 1.70E-03 1.00E+00 6.77E-03 6.17E-02 50 203 "KLHL32,PHF12,NUMB,BBS2,ZNF599,COG1,PCYT1B,SLC4A7,IGDCC3,CSNK1G3,KIAA0586,DYRK1A,KLHL5,EIF5,COQ7,SRRM1,RTN3,WAC,OGA,C15orf41,DBF4,ADGRA3,KIF5C,BCO1,RSPO2,ODF2,PDE3B,ARID4A,ZYG11B,SETD5,GSTCD,CLIP1,SCP2,KIF21A,CHD9,FNDC3A,FAM81A,SEPHS1,SPATA7,MPRIP,STXBP1,SYNE2,TCEA1,ARHGEF12,SIRT1,TRO,ZKSCAN5,KAT6A,HNRNPA3,ZDHHC20" Coexpression Atlas GSM538222_500 "B cells, B1a.PC, IgD+ IgM+ CD19+ CD43+ CD5+ CD45R+, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 1.76E-03 1.00E+00 7.00E-03 6.38E-02 74 325 "ABHD6,SNX30,SORCS2,TXNDC16,BCAR3,SEMA7A,FGD2,GAS7,CDC14B,TMEFF1,ATP2B1,NRP2,BTK,CACNA1I,CACNA1E,CAMK2D,CD86,CD38,B4GALT6,LY86,ATRNL1,RUBCN,CYBB,MYADM,SIRPA,GUCD1,RABGAP1L,EBF1,RASGRP1,FRY,PLXNC1,SRPK3,EPS8,DENND4A,TLR7,AK8,TPPP3,ACSS1,MALT1,RAB30,CECR2,TPPP,ADAMTS6,IRAK3,ITGAM,LIFR,MEF2C,AFF1,MYO5A,NAP1L1,NUCB2,PPP3CC,PRKCZ,DIRAS2,PTAFR,MARCH1,ATXN1,LMBRD1,SOX5,LHPP,SLC37A2,TCF4,DMXL2,PSD3,ARHGEF12,CYB561A3,C9orf85,LAT2,EVI5,SIGLEC10,TMEM163,PLD4,PHTF2,SSPN" Coexpression Atlas GSM854285_500 "Myeloid Cells, DC.8-4-11b+.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2" "Immgen.org, GSE15907" 1.77E-03 1.00E+00 7.04E-03 6.41E-02 92 419 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,ALCAM,SEMA7A,APP,SHTN1,CASK,ZBTB10,CADM3,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,CLU,LY86,SLC4A8,GDA,ABCG1,CSF1R,ATRNL1,CST3,SDC3,PNPLA8,CTNND1,CYBB,RASSF2,SIRPA,RABGAP1L,DSCAM,MAMLD1,DNM1L,EFNA2,PLXNC1,RASA4,ENO2,IGSF6,EXTL1,SIRPB1,ZMYND15,NEK6,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,HSF2,DOCK7,INSM1,JAK2,KTN1,TTYH2,VWA5A,MYO5A,NPR2,PFKFB3,CDK14,SSH1,CCSER2,PLCL1,PLTP,SLC22A23,PTAFR,PID1,PLEKHB2,ROGDI,SEMA6D,SCN4B,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,ST5,SULF2,TMEM150C,ARC,ATP11A,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,TRPS1,SPIRE1,WNK1,PLD4,CERS6" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_500_k3 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.77E-03 1.00E+00 7.04E-03 6.41E-02 28 98 "VAT1L,ASTN1,KALRN,NSL1,CRMP1,CRYM,SNCAIP,DUSP9,EFNA3,EYA1,GABRB3,BRD8,ADGRA3,FAM19A2,HAS2,NPTX1,CNTN3,PCDH8,PRTG,GAL3ST4,SALL1,ANKRD6,CLSTN2,ASXL3,STXBP4,ZNF184,INTS3,LRP8" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_1000 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.77E-03 1.00E+00 7.04E-03 6.41E-02 18 54 "SEMA7A,JAM2,CLU,PPP1R16B,TOX,GNE,PLXNC1,FAM198B,KITLG,PAK3,RASGEF1B,MASP1,ROBO1,RPS6KA2,SMOC1,ADHFE1,TACC1,ADAMTS9" Coexpression Atlas Facebase_ST1_e9.5_NeuroEpith_OverFaceMesench_100 e9.5_NeuroEpith_OverFaceMesench_top-relative-expression-ranked_100 FaceBase_ST1 1.77E-03 1.00E+00 7.04E-03 6.41E-02 18 54 "CPNE5,FGF17,CA4,CCNT1,JAM2,CNTFR,SCRN1,EN2,NKX6-2,MFSD2A,USP51,HES5,MT3,POU3F4,SOX2,TRH,TRPS1,FAM181B" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_500_k2 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.78E-03 1.00E+00 7.05E-03 6.43E-02 12 30 "FAM169A,DOCK4,GSDME,MEX3B,PHYHIPL,ZKSCAN3,SOX2,RBM26,KLHL4,ACTR6,ZIC3,ADAMTS9" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k5_1000 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.83E-03 1.00E+00 7.26E-03 6.61E-02 94 430 "USP31,ADGRF5,DGKZ,SHROOM2,ARRB1,NRP2,ARHGEF7,C1QC,LDLRAD4,CA8,LDB2,CD86,SCARB1,CD38,LY86,CNRIP1,CSF1R,PPP1R16B,CX3CR1,CYBB,KIF26A,RASSF2,ELMO1,FAM107B,CCDC3,ABCC9,EDNRB,EBI3,IGSF6,RCSD1,TLR7,SIRPB1,F8,DLC1,FCGR1A,FLT1,FYB1,FAM184B,PCDH17,GGTA1P,LYVE1,GPR12,NCKAP1L,ICA1,IRF8,IGF1,PIK3AP1,MAP4,TM6SF1,MEF2C,CD200,MSR1,MYO7A,NFE2L2,P2RX7,PDE2A,PDE4B,GNG2,PFKP,RELN,PTPRB,TMEM255A,ATP8B4,SGK1,FAM102A,ST8SIA1,SLA,PREX2,SMTN,SLC11A1,LIMCH1,ARHGAP26,SAMSN1,THSD1,NEK4,RGL1,SLC37A2,TAL1,KLHL4,ARHGAP9,SIK3,TEK,TF,TIE1,TLR4,TNFRSF1B,TRPC3,TTPA,VAV1,WIPF1,AMZ1,PLD4,RGS7BP,FAM13C" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k4_1000 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.84E-03 1.00E+00 7.31E-03 6.66E-02 17 50 "APLP1,MYRF,DBN1,GSDME,ALKBH8,TUBB2B,KLC1,NASP,NNAT,SNRPN,SOX2,SOX5,RBM26,ASXL3,ZIC3,PCBP4,VANGL2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k3_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.85E-03 1.00E+00 7.32E-03 6.68E-02 21 67 "CCK,CHGA,CLIP3,ATL1,TUBB4A,CORO2B,PCSK1N,GNG3,CELF3,KCNN2,LMO1,PACRG,PCBP3,SLC10A4,PRPH,RALGDS,SST,SYN1,SSBP2,TMEFF2,PCBP4" Coexpression Atlas Facebase_RNAseq_e9.5_Maxillary Arch_2500_K3 FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.85E-03 1.00E+00 7.34E-03 6.69E-02 70 305 "NDRG2,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,CACNA1B,MAP7,CBARP,MYL6B,LETMD1,MYADM,SPOCK2,C8orf34,RABGAP1L,SEMA3D,EFNA3,EGFR,FGF11,FGF12,SEMA6C,SYT3,STAMBP,TPPP3,TVP23A,GAD2,STARD10,PCDH17,GLRB,PCDH11X,NR3C1,FAM107A,FRMD3,LRRC75A,KCNK1,IL17D,MEIS1,MOV10,CCDC80,SAMD14,HS6ST3,PIRT,GPR173,SERPINE2,SMOX,FXYD1,NECAB2,RAB3A,EMID1,LGR4,ATXN7,FERMT1,CLSTN1,PALLD,DOK5,UNC5B,INKA2,ADAMTS17,MCF2L,TEX15,SLC44A1,TNNT1,CA14,TOM1L2,PORCN,NDRG4,SH3GLB2,ADAMTS9,NAV3,TMEM163" Coexpression Atlas gudmap_developingGonad_e18.5_testes_1000 DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.89E-03 1.00E+00 7.46E-03 6.80E-02 165 814 "TTYH1,ACLY,EMILIN3,TKTL1,ARID1A,DSCAML1,TMCC3,ADCYAP1R1,ADD1,ADORA1,AP2A2,AGT,TBC1D14,NR0B1,SORCS2,AK2,TAOK1,C1QTNF3,ARHGAP20,LTBP4,AMH,SEMA7A,DGKD,ARHGDIG,ARRB2,DDX3Y,BACH1,RGS11,ST3GAL5,MMD2,BTRC,DDR1,CALM1,CAMK2D,CAMK2G,VXN,CBLN1,ARHGEF1,SCARB1,CDC42,ADGRG1,JAM2,CLU,FADS2,NIPBL,RBM39,RNF14,SNCAIP,ARHGEF4,CTNND1,PUM1,ARHGAP32,DAPK3,SPOCK2,DBI,DBN1,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELAVL2,ELN,EPB41L2,LRRC17,RASL12,NRN1,TUBB3,FGFR1,FYN,GATM,CSDC2,MAP7D2,OS9,GPM6B,LPAR4,GPR37,GRB10,SPACA9,GUCY1A1,MAEL,HSD17B1,IL6ST,TUBB2B,JAK1,KCNH1,KIF2A,KLC1,LAMA2,SMAD1,MAPT,MDFI,MEF2C,MOV10,NRBP2,MT3,DDX25,MYH6,MYO7A,NEXMIF,NFIA,NFIX,NNAT,PAK3,PC,PDGFRA,SEMA5B,PLEC,FXYD1,PLP1,PCDH18,RC3H2,EXOSC10,PRKACB,PTPRE,TMEM206,MEG3,SEC14L1,SH3GL2,ARX,SLC1A6,EFHD1,SMARCA4,SNRPN,SON,SOX2,ZCCHC24,SPP1,RBM26,SULF2,ACSBG1,SYNE2,PJA1,FBXW11,TBL1X,SIN3B,USP22,OBSL1,PUM2,TEX15,HHIP,TNS1,RBFOX2,NR2C2,ZMYND8,TST,SGK3,UBTF,UCHL1,FAM181B,USP1,ZIC1,ZFAND5,INTS3,WNK1,STOX2,ADAMTS9,VPS35L,PCBP4,RTN4,ADAMTS10" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_200 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.90E-03 1.00E+00 7.51E-03 6.85E-02 16 46 "FAM135A,LDLRAD4,EDIL3,ETV1,FOXF2,MEGF10,GABRA4,GABRB1,RAB40B,IFI16,NAP1L2,PCDH8,RGS4,ZFHX4,NPAS3,SOCS4" Coexpression Atlas JC_iEC_500_K2 JC_iEC_top-relative-expression-ranked_500_k-means-cluster#2 PCBC 1.91E-03 1.00E+00 7.53E-03 6.86E-02 53 219 "ASIC2,KIAA1211,PCDH19,BBOX1,AMH,TMEM108,CACNA1E,CALB1,HAP1,CDH10,LGI1,NOG,SYNPR,TMEM155,DCC,C8orf34,MFAP3L,GRIN3A,DPP6,MAMLD1,TENM1,EN2,FOXG1,PNMA2,GAP43,DNER,MCHR1,STMN2,BVES,ARHGAP36,LRRTM3,NDP,NELL1,NRCAM,SNTG1,PCSK1,PCSK5,TRHDE,FA2H,RPE65,TMEM100,SOX8,OGDHL,SPP1,ARC,POPDC3,KLHL4,ANO4,TBX15,PCDHGB6,ASXL3,TRH,LAMP5" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_2500_K4 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 1.92E-03 1.00E+00 7.59E-03 6.91E-02 67 290 "NDRG2,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,MAP7,CBARP,MYL6B,LETMD1,MYADM,SPOCK2,C8orf34,RABGAP1L,SEMA3D,EFNA3,EGFR,MBNL2,FGF11,FGF12,STAMBP,TPPP3,GAD2,STARD10,PCDH17,GLRB,PCDH11X,NR3C1,FAM107A,FRMD3,LRRC75A,KCNK1,GATD1,KIT,IL17D,MEIS1,MOV10,CCDC80,HS6ST3,PIRT,GPR173,SERPINE2,SMOX,FXYD1,PSMD13,RAB3A,EMID1,LGR4,ATXN7,FERMT1,CLSTN1,PEX26,PALLD,DOK5,UNC5B,INKA2,MCF2L,TEX15,SLC44A1,TNNT1,CA14,TOM1L2,PORCN,NDRG4,SH3GLB2,NAV3,TMEM163" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_ureter_1000 DevelopingLowerUrinaryTract_P1_ureter_emap-30363_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.93E-03 1.00E+00 7.61E-03 6.93E-02 158 776 "TTYH1,NDRG2,TMCC3,PLEKHH1,USP31,ADGRF5,C1QTNF3,SPARCL1,ARHGAP20,PI16,APC,ATP1A2,SLC4A4,ATP2A2,MYOM1,DST,IL33,CA8,CACNA2D1,CALB1,CAMK2D,CAST,ENTPD2,REPS2,LGI1,CHGB,COL9A1,ABI3BP,MFSD4A,CP,AKAP12,GDA,OSBPL3,IPCEF1,CNTNAP2,KIAA0040,DNAJC6,ZEB2,ELMO1,MFAP3L,RABGAP1L,CCDC3,KBTBD11,CHRDL1,DNM2,CPEB2,ARRDC4,ABCC9,EBF1,EDNRB,HIPK3,SEMA3D,OPTN,ELN,CALCRL,MRVI1,F3,EFEMP1,DLC1,PRKAG2,CAP2,SORBS1,PDLIM5,FUT9,SDCBP2,DKK3,GALNT15,DNER,IGSF5,ADAM28,GFRA2,LYVE1,GLDC,RAB40B,GPM6A,TPPP,GSN,WIF1,IRAK3,RASSF8,HNMT,IFI16,RBPJ,IL6ST,SLC35G1,KCND3,KCNK1,KCNMA1,LSAMP,C2orf80,MATN2,IL17D,MSR1,MYH6,MYH7,NFIA,NFE2L2,NPTX2,NTRK2,DDR2,OPHN1,CLDN11,PENK,PIK3C2A,JAKMIP1,PRRX1,FA2H,DIRAS2,SYTL2,PTPRB,PTX3,TMEM255A,ZDHHC14,RGS4,LGI2,RYR3,S100B,SCN7A,ELMOD1,SH3BGR,SH3GL2,CPEB3,ABLIM3,SLC14A1,EFHD1,RIMS1,FNBP1,ZHX3,ATP10B,CLASP2,EPB41L3,ELOVL4,ARHGEF9,SEMA4A,TEK,TF,ZFPM2,HHIP,SLC44A1,TLR4,TNNT1,RASD2,TPM2,RGMB,SYNPO2,TRPS1,PPIL6,TMEFF2,RBFOX3,PCDH20,AGMO,KCNAB1,PLSCR4,RGS7BP,FAM13C,DOCK8,MSRB3,SOCS4" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k5 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.93E-03 1.00E+00 7.61E-03 6.94E-02 15 42 "RUNX1T1,AP4M1,EFNA3,EFNB3,CHL1,HAS2,ZNF827,PCDH8,PLTP,PRRX1,PTPRD,RNASEL,MEG3,CLSTN2,TPM2" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k3_200 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.94E-03 1.00E+00 7.62E-03 6.94E-02 23 76 "ARHGAP20,MYRF,CBLN1,CDH10,CNTFR,TENM4,ATRNL1,VCAN,EDNRA,FLNC,FREM1,GHR,GUCY1A1,GUCY1B1,MATN2,MEIS1,NCAM1,NEFM,PDGFRA,PCDH18,PRRX1,PTN,ROBO2" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.94E-03 1.00E+00 7.62E-03 6.94E-02 23 76 "NR0B1,LGR5,CDC14B,PPP4R4,ATP2B3,RGS11,SRGAP3,AFF2,SHISA6,KLHL23,KITLG,NEXMIF,TMEM206,UHRF1BP1L,TSPYL2,SMOC1,ST5,OBSL1,ZFPM2,DAAM2,FNDC5,TST,WNK3" Coexpression Atlas Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K3 FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.94E-03 1.00E+00 7.62E-03 6.94E-02 41 160 "EMILIN3,ADCY2,KIAA1324,ARHGAP20,CDK10,C1QC,CACNA1G,REPS2,CDO1,CRLF1,IGDCC3,CSF1R,CCDC3,ELN,LRRC17,FCGRT,TPK1,FYB1,ZNF276,GSN,WIF1,SYNPO,IL11RA,MBNL1,SRSF12,CD200,NFIX,CLEC9A,CNTN3,PLCL1,ZMAT4,ATXN1,LIMCH1,TNIK,ADGRL3,PHF24,TMOD1,TSPAN11,LAMP5,PMEPA1,CADM2" Coexpression Atlas GSM605805_500 "gamma delta T cells, Tgd.vg5+.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44lo, Small Intestine, avg-3" "Immgen.org, GSE15907" 1.94E-03 1.00E+00 7.63E-03 6.96E-02 91 415 "ADORA2A,MTA3,CNIH2,PKP4,APLP1,RASL11B,BMP7,BAIAP3,HIP1R,CD38,NUMBL,ADGRG1,CHN2,FADS2,OSBPL3,IPCEF1,SIPA1L1,PPP1R16B,TOX,DNAJC6,SRGAP3,RABGAP1L,ARRDC4,HEYL,OPTN,DENND4A,FDFT1,FGR,HVCN1,FYN,IGSF5,GCNT2,GPD2,B4GALNT4,GPR34,PTPN5,PADI2,FRMD5,ACOT7,HMGCR,CFAP126,AGFG1,SCIN,INPP5B,KIT,STXBP5,HECTD2,LSS,STK32C,MYO6,NEFH,P2RX7,ZNF827,PDE3B,PDE4A,PFKP,ABCB1,PLTP,SEPT4,PPP2R2C,PPP3CC,PRKACB,SYTL2,SUSD4,ZMAT4,WLS,ATXN1,SEC14L1,MRAS,SH3BP2,FAM102A,CLSTN1,ELMO2,PDZD2,TNIK,SPP1,TEX2,SULF2,ACSBG1,KLHL4,FRYL,TF,C18orf54,TNFRSF1B,TRIO,RUNDC3B,VIPR2,LAT2,PMEPA1,MVB12B,MARCH8" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_500 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.94E-03 1.00E+00 7.63E-03 6.96E-02 8 16 "CSMD3,NDRG2,LSAMP,PDE3A,PENK,SCN2A,FAM19A1,TNR" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k2_1000 kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.96E-03 1.00E+00 7.70E-03 7.02E-02 25 85 "ASIC2,MTUS1,WDR35,TXNDC16,ALCAM,OGT,CASK,ADAM23,BCHE,IL33,SPOCK2,ARRDC4,EXTL2,EZH1,WASF3,GLRB,GLUL,MEIS2,NFIX,NPR2,PENK,PLTP,NPAS3,SULF2,TPM2" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_100 kidney_P0_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.98E-03 1.00E+00 7.76E-03 7.07E-02 20 63 "AMPH,IL33,CNTFR,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,ETV1,EYA1,IGSF5,GFRA1,HAS2,NCAM1,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_200 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.00E-03 1.00E+00 7.84E-03 7.15E-02 43 170 "USP31,TAOK1,DPP10,NRP2,DST,CACNA2D1,CDH10,VCAN,HDAC9,KBTBD11,EDNRB,HIPK3,EGFR,EPHA5,TMEM132C,FOXF2,IQGAP2,GFRA1,GRIA2,GRM3,KLF12,KIF5C,RSPO2,NDP,NEFM,NFIA,CLDN11,GPR85,TRHDE,PRRX1,FAT3,PRPH,ZFHX4,SALL1,SCN3A,SOX2,EPB41L3,HHIP,RBFOX2,RGMB,SYNPO2,TRIO,MSRB3" Coexpression Atlas gudmap_developingGonad_P2_epididymis_500_k5 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.00E-03 1.00E+00 7.84E-03 7.15E-02 33 122 "ADCY8,SRPX,ATP1A2,MYOM1,VSTM2A,RGN,DCLK1,CP,MFAP3L,CHRDL1,EDNRA,ETV1,EFEMP1,FGF1,GABRB1,GAD1,LYVE1,GLUL,CNDP1,KCNC2,KCND3,MATN2,MYH3,VWA2,NPY,PENK,NALCN,VEPH1,LGI2,MRAP2,ATXN1,PCDHB9,VLDLR" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K1 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 2.02E-03 1.00E+00 7.90E-03 7.20E-02 62 265 "EMILIN3,SEMA6A,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,PCYT1B,COL9A2,ABI3BP,ANKRD44,SNCAIP,CCDC3,ABCC9,EBF1,ELN,LRRC17,FCGRT,SYT3,TRIM16,NSG1,TVP23A,DKK3,ZNF276,WIF1,RASSF8,HLF,HPSE2,SYNPO,IL11RA,CREG2,VWA5A,SRSF12,CD200,MSR1,TCEAL5,NFIX,NPY,CNTN3,PDE4D,ACSS3,IQSEC3,BEND5,RGS10,ZFHX4,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC8A1,PDZRN3,ARHGAP26,PLCB1,SATB2,PHF24,TRPS1,TSPAN11,PMEPA1" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_k4_200 kidney_e13.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.03E-03 1.00E+00 7.95E-03 7.24E-02 10 23 "VCAN,IGSF5,FREM1,NPY,PENK,FAT3,MDGA2,TSPY26P,CUX2,PCDHB9" Coexpression Atlas GSM538213_500 "B cells, B.T1.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23-, Spleen, avg-3" "Immgen.org, GSE15907" 2.09E-03 1.00E+00 8.14E-03 7.42E-02 79 353 "SNX30,ADRB2,ZNF608,TXNDC16,BCAR3,FGD2,DGKD,ATP6V0A1,BCL7A,BTK,CACNA1I,BTRC,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,RUBCN,CYBB,HDAC9,MYADM,RIPOR2,ARHGAP24,GUCD1,SLC12A6,EBF1,SNX29,RASGRP1,FRY,KCTD3,SRPK3,EPS8,TLR7,CHST15,HVCN1,ACSS1,MALT1,RAB30,EML4,CECR2,IRAK3,BACH2,IRF8,IL12A,KTN1,LIFR,PIK3AP1,GPR155,MEF2C,CD200,MX1,NUCB2,MINDY2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,PXK,MARCH1,BEND5,ZDHHC14,LRRK2,RASA3,PPM1E,ST6GAL1,LMBRD1,SLC37A2,KIAA0930,PSD3,CYB561A3,VAV2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_2500_K1 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1 FaceBase_RNAseq 2.10E-03 1.00E+00 8.17E-03 7.45E-02 101 469 "ABCF1,CEP126,PARG,APC,ZFYVE28,ADAM23,BBS2,ZNF599,DST,THSD7A,PTBP2,CCNT1,SLC16A4,CDK11B,CCPG1,ZFYVE9,COG1,C4orf33,HECTD1,MAP4K4,NIPBL,SLC4A7,TBPL1,IGDCC3,CLIP3,SUSD5,FAM169A,DZIP3,CTNND1,TBC1D5,DDX46,FAM107B,DUSP9,PHF20L1,PAN3,PLEKHO1,EPB41,CEP85L,NSRP1,WAC,SEC24B,KIAA1109,TMEM164,SMC2,MPP6,CAB39,HIGD1B,C15orf41,ARFIP1,TCERG1,ZNF638,FERMT2,RFFL,CIT,HMGB1,LRRCC1,KLHL23,TM6SF1,CPNE9,BCO1,MYO6,NASP,PIK3C2A,ANLN,EXOSC10,CEP41,MASP1,GDPD2,CCDC40,RAP1GDS1,ARID4A,RBBP8,ZYG11B,MYH14,ZFP30,PREX2,SEPHS1,SLCO1A2,TET1,INTS9,SPATA7,BDP1,C11orf87,PRRC2C,DNAJC9,ANKRD28,TAF9,TCF4,C18orf54,TJP1,LRRC8A,PARD3,TPM3,STXBP4,ZKSCAN5,XRCC4,ZNF23,EML6,CAB39L,HNRNPA3,FXR1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.10E-03 1.00E+00 8.17E-03 7.45E-02 22 72 "PCDH10,SYT13,INSYN2B,RUNX1T1,DCLK1,NTM,DLX1,TMEM132C,SGIP1,GABRB1,WIF1,ZFHX4,PRR5L,SALL1,ANKRD6,SLC15A2,LIMCH1,SOX11,TAC1,TCF4,ZFP91,ERCC6L2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_100 dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.10E-03 1.00E+00 8.17E-03 7.45E-02 22 72 "LGR5,CALB1,PLXNA4,MAGI2,PLXNC1,LRRC17,NRN1,AFF2,GABRA4,GATM,FREM1,GUCY1A1,KCND2,KLHL23,MATN2,KITLG,PDE1A,PDGFRA,PCDH18,TMEM206,ADGRL3,ACTR6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MatrixFB-A_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.11E-03 1.00E+00 8.21E-03 7.48E-02 55 230 "NDRG2,AGT,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,RASL12,DLC1,FGFR3,FHL1,UBE2E3,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NAP1L1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SCHIP1,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,ADAMTS17,TACC1,PDLIM2,TGFBR3,HHIP,VLDLR" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 1_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 1_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.11E-03 1.00E+00 8.22E-03 7.49E-02 54 225 "NDRG2,SPARCL1,LTBP4,OGT,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,EDNRA,PCOLCE2,LRRC17,ETV1,DLC1,FHL1,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,ADAMTS17,TACC1,PDLIM2,TGFBR3,HHIP,VLDLR,CAMK1G" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 1_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 1_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.11E-03 1.00E+00 8.22E-03 7.49E-02 54 225 "NDRG2,SPARCL1,LTBP4,OGT,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,EDNRA,PCOLCE2,LRRC17,ETV1,DLC1,FHL1,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,ADAMTS17,TACC1,PDLIM2,TGFBR3,HHIP,VLDLR,CAMK1G" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 2_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 2_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.12E-03 1.00E+00 8.22E-03 7.49E-02 53 220 "NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CNRIP1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,EDNRA,PCOLCE2,EML1,LRRC17,ETV1,FHL1,UBE2E3,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,ADAMTS9,CAMK1G" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 2_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Mature Fibroblast 2_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.12E-03 1.00E+00 8.22E-03 7.49E-02 53 220 "NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CNRIP1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,EDNRA,PCOLCE2,EML1,LRRC17,ETV1,FHL1,UBE2E3,DKK3,GFRA2,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,ADAMTS9,CAMK1G" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_100 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.14E-03 1.00E+00 8.29E-03 7.55E-02 26 90 "ARID1A,ADD1,CALM1,RBM39,RNF14,DBI,DBN1,DNM1L,TUBB3,FGFR1,GAP43,STMN2,GRB10,TUBB2B,KLC1,NASP,NEFM,NNAT,GNG2,MEG3,SNRPN,SON,SOX2,PUM2,PCBP4,VANGL2" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_100 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.14E-03 1.00E+00 8.31E-03 7.57E-02 24 81 "LGR5,PPP4R4,CALB1,PLXNA4,DOCK4,MAGI2,DRP2,EDNRA,PLXNC1,EMX2,GABRA4,FREM1,GUCY1A1,KCND2,KLHL23,PDGFRA,PCDH18,PRRX1,TMEM255A,TMEM206,ADGRL3,TEX15,TNNT1,VSNL1" Coexpression Atlas PCBC_ratio_SC_vs_ECTO_500 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_500 PCBC 2.15E-03 1.00E+00 8.31E-03 7.57E-02 106 496 "ADCY2,PTCHD1,PDZD4,PLA2G4C,MARCH3,ATP1A3,LDHD,CA12,CALB1,SYT6,RUNX1T1,CBS,LDB2,DCLK1,CHGA,RAB3C,RAB33A,CRYBB1,ABCG1,CRYM,GALNT9,RIMS4,KCTD8,BRINP1,NTM,RABGAP1L,CALN1,ST8SIA3,EEF1A2,LINC00599,RASGRP2,SEZ6,PIPOX,HSPA12B,PPP1R1B,OLFM1,HPCAL4,FLT1,CGREF1,MEGF11,MEGF10,HRASLS5,GABRA5,GABRB3,JPH4,MTHFD2,ATP8A2,ALDH1L1,ADAMTS8,MFSD2A,LINGO1,WIF1,C1orf94,HRH3,RIPPLY2,LRRTM3,KCNN2,KCNQ2,CAMK2N2,FGFBP3,C2orf80,MATK,MMP17,CPNE9,MT1M,SCG3,FXYD7,NOS1,NPTX1,HCN1,ZDHHC22,GDAP1L1,CAMKV,ST8SIA5,EPB41L4B,TMEM145,SLC25A48,RET,RIT2,RORB,MRAP2,RIMKLA,FERMT1,BCAN,SEPHS1,TMEM132D,OGDHL,SNCB,TNIK,HECW1,ACSBG1,SYN1,ARC,TAC3,KLHL4,TMEM151B,ARHGAP9,TEX15,TIMP4,RELL2,IL34,VIPR2,ZIC3,SLC30A3,PMEPA1,NETO1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_1000 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.15E-03 1.00E+00 8.34E-03 7.60E-02 40 156 "ABAT,KDM5D,GAS7,CADPS,DDX3Y,RGN,CDH2,CLU,SCRN1,POM121,CPEB2,DTNB,MRO,PLXNC1,SORBS3,FAM198B,PTK2B,CAMKK2,PPARGC1A,ADGRA3,GPM6B,GPR37,TUBB2B,KCNH1,CTNNA3,PAK3,RASGEF1B,PRKCB,PTCH1,ROBO1,GLDN,SOX6,MRAS,DOCK10,ST6GAL1,TNIK,BEX4,ADAMTS9,WNK3,FZD3" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.18E-03 1.00E+00 8.44E-03 7.69E-02 89 406 "ADORA1,OGT,ANK3,APC,AQP4,PDE8B,BMP7,CA4,CALB1,CANX,RGN,CRLF1,B4GALT6,CLCN3,FAM149A,COL9A3,SLC35F1,RBM39,CRYM,IPCEF1,CNTNAP2,CTH,CTNND2,FGFR1OP2,ARHGAP24,MFAP3L,DDX46,ARNT2,SEMA3D,EIF5,EIF1,EMX2,SPSB4,FGF12,SYNCRIP,SMC2,PDLIM5,RASL10A,GALC,GFRA1,PPARGC1A,MAP7D2,CNDP1,B4GALNT4,CNTRL,GRB10,GRIK2,ICA1,IGFBP1,SCIN,KCNC2,KCNJ16,KCNK1,KIF5C,L1CAM,KITLG,MYH7,NASP,NEK1,VWA2,PIK3C2A,KANSL1,MAPK4,LAMA1,RASGRF2,RET,REV3L,PRR5L,CLIP1,SALL1,SCN8A,LINC00461,SOX6,HKDC1,FHOD3,RUFY2,STX1A,TMEM150C,CAMSAP2,WWC1,WSCD1,ERCC6L2,SSBP2,RPRM,UGT8,VLDLR,VSNL1,ZNF23,NUP214" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k2_100 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.19E-03 1.00E+00 8.47E-03 7.72E-02 7 13 "ST18,INSM1,NEFM,PCDH8,CSRNP3,SOX2,ZIC3" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_500 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 2.19E-03 1.00E+00 8.47E-03 7.72E-02 41 161 "ADD3,AXIN2,OGT,LGR5,SEMA4G,PDE8B,INSYN2B,CACNA1D,MAGI2,DOCK2,RASGRP1,NRN1,GABRB1,SESN1,GRIK3,PLD5,DIPK1A,SESN3,LAYN,NEXMIF,NPR2,ENPP2,CDK14,MAPK9,GDPD1,GDPD2,CNTLN,RNASEL,SEMA6D,PRCD,TNFRSF19,STUM,KDM3A,ARHGAP26,ADAMTS17,TCF12,DAAM2,DCBLD1,LYPD6,TMEM178A,FRMD6" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_1000 dev gonad_e11.5_M_ReproVasc_Flk_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.21E-03 1.00E+00 8.52E-03 7.76E-02 161 795 "ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,ABCD2,APOC1,SHROOM2,ARRB2,MARK4,DDX3Y,ATP1B3,DOCK11,ADAM15,NRP2,ARHGEF7,C1QC,CA8,LDB2,FMNL3,CD38,ARHGEF2,MS4A7,JAM2,ABCG2,TMEM184B,LY86,CNN3,ARHGEF6,ZNF521,CRMP1,HAPLN1,CSF1R,CX3CR1,CYBB,DOCK4,TOX,KIAA0513,RASSF2,TOMM20,GIT2,PITPNC1,JAKMIP2,ELMO1,FAM107B,CCDC3,ECM2,EBF1,EDIL3,EDN1,EDNRB,YAF2,SH3GLB1,LPAR6,PLEKHA1,CALCRL,PLEKHO1,DMTN,RASGRP2,STX2,DENND4A,FAM198B,CORO2B,FCGR1A,FLT1,NOP56,TMEM107,UFM1,PDLIM5,TRIM16,FYB1,GAP43,PCDH17,GGTA1P,LYVE1,HPGDS,GLUL,LILRB4,GPM6A,LPAR4,RAPGEF4,STMN2,MAP4K5,NCKAP1L,ELOVL5,ZDHHC15,ICA1,IFI16,IGF1,TUBB2B,ITPKB,KIT,LIFR,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,MYO6,MYO9A,NEFM,NME4,CLEC9A,OPHN1,PDE2A,PDE4B,PDE4D,GNG2,SCHIP1,SPATA6,PILRA,DRAM2,MAPK3,PROX1,SLC22A23,SNRK,MDGA2,PTK2,PTPRB,TMEM255A,C1orf54,RGS3,PRR5L,SEMA6D,RASA3,SGK1,MAGI3,PREX2,BTBD3,SMTN,SLC15A2,CPEB4,LIMCH1,PEG10,SAMSN1,THSD1,SYNE2,KLHL4,TCF4,DOCK9,TEK,TF,ZFPM2,C18orf54,TIE1,HEY1,TJP1,TLR4,C9orf85,TRPC3,RFTN2,TTPA,FLRT2,WIPF1,ZNF711,NAV3,FAM13C,MRPL47,ZDHHC20,RNF146" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.22E-03 1.00E+00 8.56E-03 7.81E-02 29 104 "KDM5D,DDX3Y,ATP2B1,CDH2,SCRN1,MRO,PLXNC1,SORBS3,ERBB2,FAM198B,PTK2B,AFF2,PPARGC1A,ADGRA3,GPM6B,GPR37,PRKCB,PTCH1,ROBO1,GLDN,RPS6KA2,SOX6,MRAS,DOCK10,ST6GAL1,SPP1,SYNE2,ADAMTS9,WNK3" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k1_200 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.30E-03 1.00E+00 8.86E-03 8.08E-02 11 27 "DPP10,CDH10,GFRA1,GRM3,RSPO2,NDP,NEFM,CLDN11,GPR85,PRPH,SCN3A" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k3_200 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.30E-03 1.00E+00 8.86E-03 8.08E-02 11 27 "CLIP3,ATL1,TUBB4A,PCSK1N,GNG3,CELF3,PCBP3,SLC10A4,PRPH,SST,TMEFF2" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_1000_k2 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.30E-03 1.00E+00 8.86E-03 8.08E-02 45 181 "TTYH1,AGT,NR0B1,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,MMD2,DDR1,CBLN1,ADGRG1,CLU,NIPBL,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,BAIAP2,FYN,GATM,GPM6B,GPR37,JAK1,TTYH2,MEF2C,MOV10,MYO7A,PAK3,PDGFRA,SEMA5B,PTPRE,MEG3,ARX,EFHD1,ACSBG1,SIN3B,OBSL1,HHIP,TNS1,NR2C2,TST,SGK3,UBTF" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k4_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.31E-03 1.00E+00 8.89E-03 8.10E-02 33 123 "RNF182,CDH10,CHGB,COL9A1,DCT,GSDME,EIF4G1,CHST15,PRMT5,MEX3B,FAM19A2,INSM1,MYCN,NEFM,NODAL,LRRN3,DIRAS2,ROBO2,SOX6,ZKSCAN3,SNRPN,SOX2,SOX5,RBM26,RGL1,SULF2,KLHL4,CLASP1,HEY1,ASXL3,TPM1,ZIC3,ST8SIA2" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k3_500 kidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.31E-03 1.00E+00 8.89E-03 8.10E-02 33 123 "RNF157,MTUS1,ALCAM,AMPH,ADAM23,CACNB4,CDH2,CLIP3,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,KCNMB2,EYA1,FGFR1,SCARA3,GFRA1,TDRKH,FAM107A,HAS2,NEGR1,NCAM1,NME4,CNTN3,PENK,FAT3,MDGA2,TMEM100,SALL1,TRIM2,PCDHB9,LAMP5" Coexpression Atlas gudmap_kidney_adult_RenalCapsule_1000 kidney_adult_RenalCapsule_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.39E-03 1.00E+00 9.17E-03 8.36E-02 158 780 "ASIC2,ESYT2,MTUS1,C1QTNF3,ALCAM,SRPX,LTBP4,AMPD3,PI16,PPFIA2,UPRT,DDO,APP,SHTN1,ARNTL,DDX3Y,TMEM108,SLC4A4,DOCK11,ADAM23,BCHE,CFLAR,C1QC,RAB29,MYRF,IL33,CACNA1A,CAST,CLDN10,SLC16A4,REPS2,MS4A7,JAM2,CLU,CLTB,LY86,ARHGEF6,ABI3BP,CP,CLOCK,ANKRD44,CSF1,CSF1R,CST3,PLXNA4,CYBB,BOC,SPOCK2,CHRDL1,CDON,ECM2,EBF1,SEMA3D,TMTC1,EGFR,IRAK4,PCOLCE2,ELN,RCAN2,DENND4A,MRVI1,F3,ABCA8,PTK2B,EFEMP1,ST3GAL6,FCGRT,FGF1,FHL1,PDLIM5,FYB1,GALNT15,ERAP1,GCNT2,RAB30,LILRB4,GPM6A,GRIA4,NR3C1,GSN,GUCY1A1,IRAK3,NCKAP1L,SCRG1,HNMT,IFI16,IGF1,IL6ST,ITIH2,KCND3,KCNMA1,LAMA2,VWA5A,MATN2,MBNL1,TM6SF1,MEIS1,CD200,CCDC80,MSR1,NBL1,NFIX,NPR2,NTRK2,DDR2,NUCB2,PCDH9,PDE3A,PDGFRA,PENK,PFKP,CDK14,ABCB1,SERPINE2,PIK3R1,FXYD1,PLTP,PMP22,PRRX1,FAT3,MINDY2,NKAIN4,PKIA,PTPN13,PTPRZ1,PLEKHB2,RNASEL,ARMH4,CNTNAP3,SCN2A,MRAS,DOCK10,CNKSR2,SLCO1A2,KANK1,SULF2,SYNE2,COBL,PSD3,CYB561A3,TF,ZFPM2,TGFBR3,THBS4,SLC44A1,TJP1,TLR4,LRRC8A,TNS1,FLRT2,PLEKHH2,VLDLR,KCNT2,AGMO,KCNAB1,PLD4,PLSCR4,SSPN" Coexpression Atlas PCBC_MESO-5_fibroblast_1000 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000 PCBC 2.43E-03 1.00E+00 9.30E-03 8.48E-02 195 985 "KCNH8,CSMD3,ADCY2,ADCY8,GALNT13,SORCS1,ADORA1,NR0B1,PCDH10,UNC79,PDZD4,TRMT9B,DPP10,APOC1,LGR5,ARSE,RASL11B,KIF1A,FGF17,BMP7,BTK,C5,MYRF,CACNA1B,CALB1,MAP7,CBS,CCK,CCKBR,USP2,CDH2,CDH8,L3MBTL4,CHGA,PLEKHB1,DLGAP3,SLC24A2,FAM189A2,IGLON5,CNR1,COL9A1,COL9A2,COL9A3,GAL3ST1,TCEAL2,NRG2,CRHBP,TENM4,NCAN,CNTNAP2,PPP1R16B,PLCXD3,ARHGEF4,ARHGAP24,SV2B,KIF19,HS3ST4,CALN1,SLC25A18,DSCAM,FAM78B,USH1C,CNNM1,EFNA2,ELAVL4,ERBB4,TMEM74,RASL12,ADGRV1,FABP7,FGFR3,C1orf61,RASL10A,B3GAT1,TBR1,MEGF10,HRASLS5,GABRA5,GABRB3,GAD1,SALL3,ATP8A2,GATM,FREM1,PPARGC1A,GNAL,GPM6A,GPM6B,GPR37,TMEM121B,CECR2,GRIK3,ADAMTS8,GRM2,PTPN5,FAM222A,HAS2,HBA1,NXPH2,NCKAP1L,IGFBPL1,HP,SHISA6,NKD1,ZNF385B,LRRTM1,C2CD4C,KCND2,KCNF1,KCNH1,CLVS2,KCNJ3,KCNJ5,KCNN1,KCNQ2,KIF5C,KIT,MATN3,SCG3,MYT1,NODAL,NPPA,HCN1,IGSF11,PAX6,PCDH8,PCSK2,PRTG,SLC10A4,SEMA5B,A2ML1,JAKMIP1,HMGCLL1,PDZRN4,MAGEL2,PACSIN1,RASGEF1B,RAB39A,RELN,LAMA1,ELOVL2,STK32A,PTPRD,SLC25A48,FAM184A,KHDRBS2,PRIMA1,MRAP2,SYNDIG1,RXRG,SALL1,SEMA6D,TMEM200C,SH3GL2,ST8SIA1,ANKRD6,SLC1A6,SLCO1A2,SOX10,MCF2L2,NFASC,SSTR2,ZFR2,TMEM150C,COBL,TAC3,PHF24,FAM189A1,LEFTY2,GALNT17,TMOD1,FAM124A,PIK3R5,SEZ6L,TRPM2,CA14,RPRM,FAM181B,VIPR2,RBFOX3,PORCN,ETNPPL,KCNK12,ZIC2,ZIC3,KCNT2,FMN2,PLPP4,ANKS1B,CADM2,SHD,GAL3ST3,DOCK8,FAM198A,JPH3" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k1 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.45E-03 1.00E+00 9.37E-03 8.54E-02 16 47 "EMILIN3,ADRB2,MYOM1,COL9A1,PLCXD3,NCALD,CAP2,DKK3,MEGF10,GFRA2,LIMS1,NPTX2,NALCN,SH3BGR,HHIP,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k4 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.45E-03 1.00E+00 9.37E-03 8.54E-02 16 47 "THSD7A,AIF1L,SGIP1,GABRA4,ILDR2,GRM7,MAPT,SYT9,SCHIP1,PTPRO,DUSP15,SCN7A,DDN,TMEM150C,TMEM178A,CERS6" Coexpression Atlas GSM605827_500 "Myeloid Cells, DC.8+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 2.45E-03 1.00E+00 9.37E-03 8.54E-02 87 397 "FMNL2,ADORA3,RNF150,ADRB2,ADGRF5,ALCAM,FGD2,SHTN1,TMEFF1,ARHGAP5,N4BP2L1,ADAM23,ST3GAL5,BTK,CACNA1E,CD86,CD38,CD81,CHN2,ZFYVE9,LY86,FAM149A,SLC4A7,CST3,SDC3,CTNND1,CYBB,SRGAP3,ARRDC4,PLXNC1,PLEKHA1,PLEKHO1,EPS8,IGSF6,OLFM1,FLT1,TMEM107,DKK3,GALC,NEK6,GATM,RAB30,GPR34,MAP4K5,HPS5,IRF8,LRRC25,DOCK7,KIT,LIFR,MRPL42,ADAM22,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,PFKFB3,CDK14,PRKAB2,RASGEF1B,RAB39A,SLC22A23,PTAFR,PID1,C1orf54,ROGDI,SNX22,PRR5L,ACER3,LRRK2,RTN1,TMEM156,SLC8A1,CCDC88A,SLC11A1,SLC12A2,FNBP1,SULF2,SEPT3,ADGRL3,CYB561A3,TPD52,TRPM2,TUBB2A,CADM1,PLD4" Coexpression Atlas GSM854243_500 "Myeloid Cells, DC.103+11b-.LuLN, MHCII+ CD11c+ CD8- CD11b- CD103+, Lymph Node, avg-3" "Immgen.org, GSE15907" 2.46E-03 1.00E+00 9.39E-03 8.56E-02 83 376 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,APP,SHTN1,CASK,ARHGAP5,CAPRIN2,ZBTB10,ATP2B1,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,CLU,LY86,SLC4A8,CSF1,CST3,SDC3,MYADM,PLPPR4,RABGAP1L,ARRDC4,PLXNC1,RASA4,ENO2,MTSS1L,EXTL1,ZMYND15,NEK6,MTHFD2,RAB30,ADAP1,SLC2A6,GYG1,HSF2,DOCK7,SCIN,INSM1,TUBB2B,JAK2,VWA5A,NCOA7,ASPRV1,CD200,CLEC9A,PBX1,PFKFB3,CDK14,CCSER2,SLC22A23,ROGDI,ZDHHC14,RGS12,PRR5L,SEMA6D,SCN4B,ARHGEF40,CCDC88A,SAMSN1,SSPO,STXBP1,ARHGEF9,TMEM150C,ARC,PHF24,SLC44A1,DDHD1,TNFRSF1B,TRPS1,ZBTB38,SPIRE1,WNK1,ITM2C" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k3 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.52E-03 1.00E+00 9.63E-03 8.78E-02 15 43 "CA4,CA12,CALB1,ISPD,EMX2,IGSF5,KCNC2,CLEC18A,MYO6,RETREG1,RYR3,SCN8A,SATB2,TF,ZFP91" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k4 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.53E-03 1.00E+00 9.66E-03 8.81E-02 26 91 "LCORL,CACNB2,CHM,NMT2,ABI3BP,RBM39,FGFR1OP2,GSDME,G3BP2,CALCRL,EMX2,SCML2,KIAA1109,GABRA4,ILDR2,DNER,NR3C1,KIF3A,SUSD4,TMLHE,FNIP1,SLC12A2,SP4,CLSTN2,SYNE2,ADAMTS9" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k2 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.54E-03 1.00E+00 9.71E-03 8.85E-02 22 73 "CFL2,CNTN1,DNAJC6,MFAP3L,CPEB2,TMTC1,NRN1,PRKAG2,CGREF1,DKK3,IL6ST,KCNMA1,NFIX,HCN1,PPP3CA,PTHLH,CLIP1,RYR3,HHIP,SYNPO2,UCHL1,FAM13C" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_200_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.55E-03 1.00E+00 9.71E-03 8.85E-02 13 35 "CNTN1,COL9A1,MRVI1,DACH2,DKK3,NEGR1,KCND3,CLDN11,PENK,PTX3,SH3BGR,ANO4,SYNPO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_100_k1 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.55E-03 1.00E+00 9.72E-03 8.86E-02 9 20 "EMILIN3,GFRA1,GRIA2,FAT3,REV3L,SMOC1,EPB41L3,RBFOX2,RGMB" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_1000 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.57E-03 1.00E+00 9.77E-03 8.91E-02 24 82 "APOC1,CDC14B,SRGAP3,PLXNC1,FAM198B,AFF2,ZMAT1,GATM,ADGRA3,GPM6B,GPR37,RABL2A,MOV10,MXI1,NELL1,ETFRF1,PRKCB,RPS6KA2,SMOC1,SYNE2,OBSL1,TST,ADAMTS9,WNK3" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 2.60E-03 1.00E+00 9.86E-03 8.99E-02 29 105 "NCKAP5,GRAMD1B,SEMA6A,APAF1,APOC1,ATP1A3,LDB2,SCARB1,ABCC9,RASGRP2,DLC1,TMEM164,LPAR4,ELOVL5,HMGCR,ZDHHC15,KCNJ3,LSS,MEF2C,LAYN,NPY,TMEM255A,SLC6A15,ACSBG1,ARHGEF9,PCDHB10,RFTN2,VSNL1,PMEPA1" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K5 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#5 FaceBase_RNAseq 2.60E-03 1.00E+00 9.86E-03 8.99E-02 29 105 "ACTN2,ADCY2,ARHGAP20,ADGRB2,BARD1,C1QC,LDLRAD4,CAMK2A,REPS2,KCNAB3,CSF1R,DLG2,FYB1,TMEM8B,GRIA1,ZNF385B,KLHL23,PDE1A,PLCL1,MASP1,DEF8,ZMAT4,SLC1A2,ADGRL3,FAM189A1,EML6,CADM2,PCDH15,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2 DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.60E-03 1.00E+00 9.86E-03 8.99E-02 29 105 "ANK1,APC,MYOM1,NRP2,CACNA2D1,CAMK2D,CPEB2,ABCC9,HIPK3,MRVI1,FHL1,SORBS1,DKK3,PRUNE2,KCNMA1,MBP,PRKCB,RYR3,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,RIMS1,TPM2,SYNPO2,PPIL6,RBFOX3,MSRB3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.61E-03 1.00E+00 9.90E-03 9.02E-02 52 217 "NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,RCAN1,EDNRA,PCOLCE2,BSCL2,LRRC17,ETV1,FHL1,UBE2E3,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,CCDC80,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,ADAMTS17,PDLIM2,TGFBR3,HHIP,TUBA1A,ST8SIA2" Coexpression Atlas ratio_EB_vs_SC_2500_K4 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 2.61E-03 1.00E+00 9.90E-03 9.02E-02 64 278 "SERPINA3,AGT,SPARCL1,PHYHD1,ARHGDIG,CHRD,B3GALT2,MYOM1,CAMK2A,CAPN3,MYOM2,AKAP6,CREB5,MROH8,RASGEF1C,CFAP61,DMD,CD99L2,ECM2,SYT15,ABCA8,GTF2IRD2,FLNC,CHL1,CYP46A1,CSDC2,GGT5,GPR17,TPPP,FAM107A,ATOH8,UBE2QL1,HAPLN2,ALDH1L1-AS2,IGF1,IL11RA,PACRG,MAPT,MITF,MYL3,NCAM1,PDE1C,PLCL1,PMP22,PTH1R,CRTAC1,RNASE1,TMEM100,CCDC92,SLC6A1,SLC8A1,FAIM2,GPRIN3,HEY1,TNS1,SYNPO2,FNDC5,PDIA2,TMEM161B-AS1,TOM1L2,BEST1,SLC26A10,ZBTB16,DPF3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_200 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.62E-03 1.00E+00 9.92E-03 9.04E-02 19 60 "FMNL2,ATP2B3,CHRM4,DOCK4,DAPK1,KLHL5,EMX2,NRN1,GABRB1,KLHL23,KITLG,MYO9A,TMEM206,TNFRSF19,RASA3,SLC4A3,KDM3A,ACTR6,FNDC5" Coexpression Atlas PCBC_ratio_DE_vs_SC_500 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500 PCBC 2.62E-03 1.00E+00 9.93E-03 9.05E-02 106 499 "KCNH8,ACHE,SORCS1,ERMN,MTUS1,NR0B1,ARHGAP20,PCDH10,TRMT9B,LGR5,SLC7A14,ARRB1,ARSE,FGF17,CFLAR,C5,IL33,LDLRAD4,CCKBR,CDH2,CDH10,COL9A2,CRHBP,TENM4,CSF3R,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,C8orf34,LYPD1,SPOCK3,CCDC3,LPAR6,DMTN,DLC1,AMOTL2,C1orf61,FLNC,C2orf88,RASL10A,TBR1,DKK3,CHL1,GAD1,FREM1,PCDH17,FAM222A,HAS2,CDH20,KCNF1,CLVS2,MATN3,LRP1B,MOBP,SAMD5,NBL1,NODAL,OLR1,PAX6,SERPINE2,GPSM2,PDZRN4,PACSIN1,RASGEF1B,RELN,PTHLH,PTH1R,ELOVL2,ACSS3,FAM184A,PRIMA1,ZFHX4,WLS,RXRG,CCDC92,SMARCD3,SOX5,MCF2L2,NFASC,EPB41L3,SULF2,TMEM150C,ZFPM2,LEFTY2,HHIP,TMOD1,RIMBP2,PIK3R5,SEZ6L,TRPM2,CADM1,RPRM,PDIA2,FLRT2,TOM1L2,KCNK12,FMN2,PLPP4,ANKS1B,MEIS3,PMEPA1,ADAMTS9,PLSCR4" Coexpression Atlas Lungmap Mouse Lung E16.5 Epithelial Subtype Proliferative AT1 Progenitor Lungmap Mouse Lung E16.5 Epithelial Subtype Proliferative AT1 Progenitor Lungmap CCHMC 2.63E-03 1.00E+00 9.94E-03 9.06E-02 94 435 "ACLY,AS3MT,CDC7,MTA3,SPARCL1,USP37,CHID1,MPDZ,PLEKHB1,CNN3,CNRIP1,CLIP3,LRIG1,VCAN,ZEB2,GOLT1B,EDNRA,EDNRB,STARD3NL,PLEKHO1,RABEPK,ETV1,GMPR2,EFEMP1,TOMM40L,FGF1,PCYOX1,NOP56,NELFCD,WDR83,PNMA2,NEK6,GART,FREM1,GHR,GUCY1A1,GPR45,ACOT7,IGF1,TTYH2,LAMA2,MAOB,LYPLAL1,LDLRAD3,MEF2C,MEIS1,SCAMP5,NFE2L2,DDR2,PDE4B,PDGFRA,PLTP,PLXNB1,MED1,PPP3CA,KANSL1,NKAIN4,PPP5C,MAPK3,APTX,PSMD13,PTH1R,PTPRD,FAT4,SLC25A36,RIC8B,ZFHX4,ROBO2,CCDC25,TMEM100,ATAT1,WLS,RTKN,SCN2B,FAM102A,MAGI3,CCDC88A,SMARCD3,SNRPN,PALLD,SOX5,SOX11,KDM3A,SS18,DNAJC9,MGRN1,HHIP,TRIO,VSNL1,PCDH20,TUBA1A,NAV2,PLSCR4,IFT88" Coexpression Atlas GSM854332_500 "Myeloid Cells, Mo.6C-II-.BM, B220neg CD3neg CD115+ Ly-6C/Glo CD43+, Bone marrow, avg-3" "Immgen.org, GSE15907" 2.72E-03 1.00E+00 1.03E-02 9.39E-02 89 409 "ADRB2,MTUS1,ABCD2,FGD2,SUGT1P4-STRA6LP-CCDC180,APOC2,APP,ATP1A3,ST3GAL5,RAB29,SCARB1,ADGRG1,ZFYVE9,FADS2,LY86,CDC42BPB,GDA,CSF1R,CSF2RA,CSF3R,GALNT9,CST3,SDC3,CX3CR1,CYBB,MYADM,KIAA0513,DGKG,DBI,SIRPA,RCAN1,TOM1,EBI3,RASA4,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FGR,PCYOX1,TPPP3,IP6K3,GCNT2,ADAP1,SLC2A6,ATG4C,IRAK3,PADI2,HP,IRF8,LRRC25,IL6R,ITGAM,L1CAM,STMN1,LMO2,PIK3AP1,NAT8L,LDLRAD3,NCF2,PFKFB4,CDK14,PLTP,PILRA,MAPK3,PID1,C1orf54,ARHGEF10L,PRR5L,ACER3,RPS6KA2,ST6GALNAC6,RTN1,SH3BP2,SLC11A1,ELMO2,RAP1GAP2,FGD4,KIAA0930,TF,TGFBR3,TNFRSF1B,TPD52,LAT2,ZBTB16,PLD4,NLRP3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k1 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.73E-03 1.00E+00 1.03E-02 9.39E-02 30 110 "ADORA1,EPB41L5,SNCAIP,CDHR1,EYA1,ST3GAL6,IGSF5,FREM1,GRM3,IFI16,KCNA1,LIG4,TM6SF1,NCAM1,NELL1,OXTR,PRTG,FAM184A,GAL3ST4,PRR5L,SALL1,ANKRD6,CMTR2,CLSTN2,NEK4,ANKRD28,ACSL6,PCDHB9,HEY1,RGMB" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_FB-A_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_FB-A_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 2.74E-03 1.00E+00 1.03E-02 9.43E-02 67 294 "SDE2,ACTN1,NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,GPSM1,DOCK4,BRINP1,ZEB2,EDNRA,MRNIP,PCOLCE2,EPB41L2,LRRC17,NCALD,ETV1,FHL1,CINP,DKK3,ZMYND11,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,DDR2,PBX1,PDGFRA,SERPINE2,FXYD1,ANKRD16,PMP22,SCHIP1,SEPT4,NKAIN4,BCAS3,PTCH1,ZCWPW1,SEC61A2,ZFHX4,ROBO1,ROBO2,TNFRSF19,SMARCE1,LIMCH1,PALLD,GANAB,PDLIM2,TGFBR3,HHIP,CBX5,SSBP2,EIF4ENIF1,RNF170" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_FB-A_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_FB-A_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 2.74E-03 1.00E+00 1.03E-02 9.43E-02 67 294 "SDE2,ACTN1,NDRG2,SPARCL1,LTBP4,CACNA1D,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,GPSM1,DOCK4,BRINP1,ZEB2,EDNRA,MRNIP,PCOLCE2,EPB41L2,LRRC17,NCALD,ETV1,FHL1,CINP,DKK3,ZMYND11,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,NRCAM,DDR2,PBX1,PDGFRA,SERPINE2,FXYD1,ANKRD16,PMP22,SCHIP1,SEPT4,NKAIN4,BCAS3,PTCH1,ZCWPW1,SEC61A2,ZFHX4,ROBO1,ROBO2,TNFRSF19,SMARCE1,LIMCH1,PALLD,GANAB,PDLIM2,TGFBR3,HHIP,CBX5,SSBP2,EIF4ENIF1,RNF170" Coexpression Atlas GSM538282_500 "Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3" "Immgen.org, GSE15907" 2.74E-03 1.00E+00 1.03E-02 9.43E-02 92 425 "TMCC3,ADRB2,BEND6,BCAR3,ABCD2,APP,SHTN1,CPNE5,CASK,ASPH,ATP6V0A1,NRP2,DST,CA4,VSTM2A,CH25H,MTMR7,FAM189A2,LY86,CDC42BPB,GDA,ABCG1,CSF1R,SDC3,PNPLA8,CTNND1,CYBB,DOCK4,MYADM,ARHGAP24,DAPK1,SIRPA,ARRDC4,ABCC5,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FCGRT,FGR,PCYOX1,FLT1,HVCN1,AK8,TPPP3,NEK6,GCNT2,GGTA1P,GLUL,PRUNE2,ATG4C,DOCK7,KCNN3,TTYH2,LAMP2,PIK3AP1,GPR155,MATN2,MITF,CCDC80,MYO6,P2RY13,NCF2,NUCB2,OLR1,CDK14,ANLN,SNX10,PLTP,LRP12,SLC36A4,PILRA,RASGEF1B,SGK1,CCDC88A,SPP1,NXT2,SULF2,FGD4,SYNE2,ADGRL3,DMXL2,TCF7L2,CYB561A3,TF,DDHD1,TLR4,TNS1,AGMO,PLD4,NLRP3" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K2 FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 2.75E-03 1.00E+00 1.04E-02 9.45E-02 34 129 "AMPD2,IGDCC4,GPC2,PCYT1B,CLIP3,C8orf34,ACOT8,BAIAP2,SGIP1,NBEA,TMEM151A,HIGD1B,RAB30,RAPGEF4,WIF1,HLF,SMAD9,CPNE9,SAMD5,N6AMT1,NPY,PDE4D,PFKFB2,DIRAS2,RAP1GAP,CNKSR2,ARHGAP26,ARHGEF9,KAZN,PHF24,HIF3A,LEFTY2,STXBP4,CERS6" Coexpression Atlas GSM605862_500 "Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3" "Immgen.org, GSE15907" 2.76E-03 1.00E+00 1.04E-02 9.46E-02 95 441 "ALCAM,ABCD2,GAS7,APP,SHTN1,CDC14B,CASK,ATP1A3,ATP6V0A1,ADAM15,ST3GAL5,C1QC,CD38,B4GALT6,JAM2,TPP1,LY86,GDA,CSF1R,CST3,SDC3,CTNND1,CYBB,MYADM,KIAA0513,DAPK1,SIRPA,ZEB2,DNM1,FAM78B,EDIL3,EDNRB,EPS8,IGSF6,ETV1,TLR7,F5,FAM198B,FABP7,FCGR3A,FCGRT,FER,FGFR1,PCYOX1,FOLR2,AK8,GAA,GALC,LYVE1,HPGDS,GLUL,KIF3A,GYG1,ATG4C,VSIG4,HNMT,IGF1,LRRC25,DOCK7,ITGAM,TTYH2,LAMP2,LYPLAL1,MITF,MSR1,TREM2,CDK14,PLTP,PMP22,LRP12,SLC36A4,PILRA,DRAM2,RASGEF1B,GDPD1,PTAFR,PID1,RNH1,ACER3,LRRK2,ITSN1,SLC11A1,SPP1,NXT2,FGD4,ARHGEF12,TF,TLR4,TMOD1,TNS1,LAT2,AGMO,EVI5,PLSCR4,MARCH8" Coexpression Atlas gudmap_developingGonad_P2_ovary_500_k4 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.76E-03 1.00E+00 1.04E-02 9.46E-02 40 158 "PLA2G4C,ABI3BP,MYRIP,GDA,TENM4,CSNK1E,PLXNA4,GSDME,SNAP91,G3BP2,SLC12A6,ATL1,ELAVL2,DNER,GDF9,KIF3A,SHISA6,KIT,SYTL4,RSPO2,NOS1,SETD4,ABCB1,MAPK10,GDPD1,STK32A,SUSD4,IL17RB,KIF16B,CPEB3,SLC14A1,CLSTN2,CAMTA1,MTMR14,PARD3,TBC1D15,TRIM9,NDRG4,FAM47E,DPF3" Coexpression Atlas facebase_RNAseq_e10.5_Emin_LatNas_2500_K4 facebase_RNAseq_e10.5_Emin_LatNas_2500_K4 Gudmap RNAseq 2.76E-03 1.00E+00 1.04E-02 9.46E-02 21 69 "PCDH19,DOC2A,NOL4,BMPR1B,DUSP9,EMX2,KCNMB2,FGF12,FRMD5,KCNC1,MAPK4,NKAIN1,NUDT11,GLDN,RIMKLA,SCG5,SOX11,TMEM150C,BEX4,LYPD6,ANKS1B" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_500_k2 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.85E-03 1.00E+00 1.07E-02 9.75E-02 31 115 "ANK1,MYOM1,NRP2,CAMK2D,DMPK,CPEB2,DTNA,ABCC9,SORBS1,IGSF5,PRUNE2,BVES,IL6ST,NPTX2,PFKP,PRKCB,PTHLH,RYR3,STUM,SH3BGR,LIMS2,RIMS1,DBNDD2,POPDC3,TNNT1,TNS1,TPM1,TPM2,SYNPO2,RBFOX3,RGS7BP" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K2 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 2.93E-03 1.00E+00 1.10E-02 1.00E-01 62 269 "PLEKHG5,ERMN,CACHD1,PDXK,TTLL9,SLC25A14,PPT2,LRRC3B,GPSM1,HDAC9,MYADM,ARHGAP24,WDR20,CEND1,FGF11,FGFR1,FOXF2,JPH4,GFRA2,CSDC2,GSN,GUCY1A1,HMGCL,METTL21A,CDH20,GATD1,KHK,MATN2,CD200,CCDC80,OGG1,PENK,ZFYVE21,PLEC,FTO,PMP22,MAGEL2,PPP3CC,NKAIN4,PRODH,PTPRE,PTPRG,TSPY26P,C12orf49,BAALC,KIAA0895L,PRR5L,STK32B,FOXRED2,SBF1,NTNG1,SLC4A3,ELMO2,PALLD,PDZRN3,ADAMTS17,KAZN,TMEM121,SH3GLB2,CA10,MSRB3,ADAMTS10" Coexpression Atlas GSM791122_500 "Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2" "Immgen.org, GSE15907" 2.93E-03 1.00E+00 1.10E-02 1.00E-01 89 410 "FMNL2,CDC7,ZNF608,OSBPL1A,CDC42BPA,GPAM,BLM,PRC1,ADGRG1,B4GALT6,FADS2,ABCG2,CNN3,ZNF521,CNRIP1,CSF3R,DZIP3,CTNND1,GPRASP1,ARHGAP32,SIRPA,ARMCX4,EBF1,EBI3,PLXNC1,CALCRL,EYA1,ARMCX1,NBEA,SMC2,GATM,GCNT2,SESN1,CECR2,GRB10,PRDM5,GSTM5,GUCY1A1,IRAK3,HLF,ICA1,DOCK7,LRRCC1,IL12A,KLHL23,KIT,STMN1,LMO2,LYPLAL1,MEF2C,MEIS1,MEST,MYCN,RCOR2,NME4,OCRL,PBX1,ANLN,LRRC49,SEC61A2,RNASEL,ACER3,ITSN1,PPP1R9A,BTBD3,SLC12A2,TET1,PEG10,SAMSN1,THSD1,CEP68,FGD4,SYNE2,KLHL4,HIF3A,TEK,TIE1,TJP1,CBX5,BHLHB9,NPL,STXBP4,SSBP2,TTC3,TTPA,VIPR2,PHTF2,MSRB3,NETO2" Coexpression Atlas ratio_DE_vs_SC_500_K5 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5 PCBC 2.95E-03 1.00E+00 1.10E-02 1.01E-01 68 300 "KCNH8,SORCS1,ERMN,NR0B1,PCDH10,TRMT9B,LGR5,SLC7A14,ARSE,FGF17,C5,CCKBR,CDH2,CDH10,COL9A2,CRHBP,TENM4,CSF3R,IPCEF1,CNTNAP2,PLXNA4,PLCXD3,C8orf34,SPOCK3,C1orf61,FLNC,RASL10A,TBR1,DKK3,FREM1,PCDH17,FAM222A,HAS2,KCNF1,CLVS2,MATN3,LRP1B,MOBP,NODAL,SERPINE2,PDZRN4,PACSIN1,RASGEF1B,ELOVL2,ACSS3,FAM184A,PRIMA1,RXRG,SMARCD3,SOX5,MCF2L2,NFASC,TMEM150C,LEFTY2,TMOD1,PIK3R5,SEZ6L,TRPM2,CADM1,RPRM,PDIA2,TOM1L2,KCNK12,FMN2,PLPP4,ANKS1B,MEIS3,PMEPA1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgle_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl_Subtype_eRgle_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 2.95E-03 1.00E+00 1.11E-02 1.01E-01 73 326 "ZNF608,SPARCL1,SGCE,ARHGEF25,CBLN1,CDH2,CDH18,CDO1,CDR1,CLU,COL4A5,COL9A1,ZNF521,SLC35F1,CNTNAP2,PABPC5,RCAN1,SEZ6L2,ING4,ERBB2,NRN1,ABCA8,TMEM132C,ZIC4,TMEM164,CAP2,TMEM107,ERGIC3,SALL3,GRM8,ITPKB,OLFM3,KCNQ3,KIT,LAMP2,LRP1B,CCDC80,RSPO2,NFIA,NUCB1,NUCB2,CNTN3,PAX6,PFKP,PKM,PLTP,GDPD2,USP47,FAT4,RFX3,RFX4,ZFHX4,WLS,S100B,GALNT10,KANSL3,PALLD,SYNE2,PDLIM2,TCF12,AHCYL2,TEX15,AKTIP,TRH,CA14,FAM181B,ZIC1,ZIC2,DNALI1,SLC38A1,ADAMTS9,NHSL1,SSPN" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k1 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.96E-03 1.00E+00 1.11E-02 1.01E-01 32 120 "ADORA1,PDE8B,BMP7,CALB1,CRLF1,COL9A3,IPCEF1,CNTNAP2,CTNND2,EMX2,SPSB4,FGF12,RASL10A,GFRA1,MAP7D2,GRIK2,L1CAM,KITLG,MYH7,VWA2,MAPK4,LAMA1,RASGRF2,RET,PRR5L,SCN8A,FHOD3,TMEM150C,WWC1,WSCD1,RPRM,VSNL1" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_200_k2 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.96E-03 1.00E+00 1.11E-02 1.01E-01 17 52 "ADORA1,PCDH19,DOC2A,SLC32A1,KIAA0040,GREB1,EPHB1,ST3GAL6,FKTN,ADGRA3,HES5,CLEC18A,NPY,OXTR,TMEM100,EMID1,HEY1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_200 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.96E-03 1.00E+00 1.11E-02 1.01E-01 17 52 "KLHL13,PLXNA4,MAGI2,EMX2,NRN1,GABRB1,TCEAL6,MAP2,KITLG,NFIA,PDE1A,PCDH18,STUM,SLC4A3,ADGRL3,TNNT1,LYPD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k2 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 2.98E-03 1.00E+00 1.11E-02 1.01E-01 10 24 "SORCS1,PCDH10,BRINP1,FOXF2,SGIP1,MEGF10,GABRB1,IFI16,ZFHX4,ANKRD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k5 DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 2.98E-03 1.00E+00 1.11E-02 1.01E-01 10 24 "DCLK1,CDO1,SPOCK3,STMN2,IFI16,NEFM,RTN1,SNAP25,SCN3B,C11orf87" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_100_k4 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 2.98E-03 1.00E+00 1.11E-02 1.01E-01 10 24 "CRYM,ELAVL4,EYA1,FAM19A2,FAM107A,HAS2,PRTG,SALL1,MAPK12,ANKRD6" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_200 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 2.98E-03 1.00E+00 1.11E-02 1.01E-01 10 24 "NR0B1,LGR5,AFF2,SHISA6,KLHL23,SYTL4,TMEM206,SMOC1,DAAM2,WNK3" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500_k1 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.99E-03 1.00E+00 1.11E-02 1.01E-01 26 92 "ADD3,ARHGAP20,PCDH10,ATP2B1,IL33,VSTM2A,DCLK1,COL4A5,EDNRA,TMEM132C,GABRB1,GAD1,GRM7,RASSF8,KLF12,KCND3,NFIA,PENK,NALCN,FAT3,PTN,LGI2,MEG3,PCDHB9,HIF3A,VLDLR" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_100 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 2.99E-03 1.00E+00 1.11E-02 1.01E-01 26 92 "NR0B1,PPP4R4,TMEM108,CALB1,CBLN1,CDH10,DCLK1,HAPLN1,PLXNA4,DOCK4,DRP2,EMX2,GABRA4,FREM1,PCDH11X,GUCY1A1,KCND2,KLHL23,NEFM,PDGFRA,SERPINI1,PCDH18,ADGRL3,ZFPM2,ACTR6,DPF3" Coexpression Atlas Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(2) Lungmap Mouse Lung PND3 Endothelial Subtype Endothelial-B(2) Lungmap CCHMC 2.99E-03 1.00E+00 1.11E-02 1.01E-01 67 295 "ABCF1,SYN3,NCKAP5,SPARCL1,SEMA6A,SEMA7A,PRX,DYNLL1,GPR146,SGCE,CA4,LDB2,SCARB1,CD81,DLGAP3,CNN3,PPP1R16B,GIT2,PITPNC1,MED12,EDIL3,EDN1,EDNRB,PLEKHA1,CALCRL,RCSD1,TUBA1B,FLT1,NSG1,FYN,PCDH17,LYVE1,FERMT2,STMN2,GABARAPL2,NKD1,TUBB2B,MAPT,MEST,KITLG,CD200,NELL1,PCBP3,PCSK5,PDE4B,SEPT4,PTPRB,PTPRG,RDX,RGS12,TMEM100,RTN1,SCN7A,SGK1,UNC5B,THSD1,PLCB1,TACR1,PDLIM2,TCF4,ARHGEF12,TEK,TIE1,TJP1,TPM4,TUBB2A,TUBA1A" Coexpression Atlas gudmap_developingGonad_P2_ovary_500_k2 DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 2.99E-03 1.00E+00 1.11E-02 1.01E-01 20 65 "PNMA8B,PKP4,BACH1,CHM,RBM39,EIF4G1,EPB41L2,ILDR2,LPAR4,CHIC1,MMP16,PDPK1,TMLHE,SLC12A2,ZC3H13,SYNE2,CBX5,SSBP2,ADAMTS9,GAN" Coexpression Atlas gudmap_developingGonad_e11.5_testes_500 DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.02E-03 1.00E+00 1.12E-02 1.02E-01 94 437 "ACLY,ARID1A,ADD1,NR0B1,EPB41L5,APLP1,BACH1,BTRC,DDR1,CALM1,CAMK2G,INA,COL9A1,RBM39,CRMP1,RNF14,CLIP3,CSNK1E,PUM1,ARHGAP32,DAPK1,DAPK3,DBI,DBN1,DCTN1,BLOC1S6,GSDME,DNM1L,EDNRA,MBNL2,ELAVL4,EPB41L2,FABP7,TUBB3,FGFR1,MEX3B,DPYSL4,DLL3,GAP43,KIAA1958,OS9,LPAR4,STMN2,GRB10,BACH2,NKD1,INSM1,TUBB2B,KLC1,MAPT,TAGLN3,NASP,NCAM1,NEFM,NNAT,GNG2,OLA1,PIK3R1,RC3H2,EXOSC10,PRKACB,ZIK1,RFX4,ZFHX4,MEG3,LINC00461,SFPQ,SCG5,ARX,SMARCA4,SNRPN,SON,SOX2,ZCCHC24,CAND2,RBM26,SPART,TROVE2,SYT11,FBXW11,KLHL4,TRIM2,PUM2,ZMYND8,TST,USP1,ZIC1,ZIC3,ZFAND5,INTS3,STOX2,PCBP4,RTN4,VANGL2" Coexpression Atlas geo_heart_1000_K4 geo_heart_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 3.02E-03 1.00E+00 1.12E-02 1.02E-01 38 149 "HHATL,LCNL1,HFM1,PI16,VXN,RGN,CHGB,FAM189A2,TOGARAM2,CRYM,KCNMB2,RAB9B,F5,FGF1,DKK3,CPLX1,TUBA8,GFAP,PPARGC1A,GRIN2C,HP,FAM95B1,KIAA1755,KCNJ3,KCNJ4,KCNK3,MYBPC1,MYH6,NPPA,PACSIN1,SGSM1,HOGA1,SLN,IDI2-AS1,CLSTN2,ABCC8,REEP1,SHD" Coexpression Atlas GSM777021_500 "B cells, B.Fo.MLN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-3" "Immgen.org, GSE15907" 3.03E-03 1.00E+00 1.12E-02 1.02E-01 76 342 "SNX30,ZNF608,TXNDC16,BCAR3,CARNS1,BIN1,FGD2,SUGT1P4-STRA6LP-CCDC180,ATP6V0A1,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,SLC4A7,CSNK1G3,KIAA0040,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,SRPK3,TLR7,HVCN1,RAB30,DCLK2,EML4,RAPGEF4,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,DIPK1A,LMO2,PIK3AP1,MEF2C,CD200,SESN3,MYO5A,NCF2,SERPINI1,PPP3CA,PPP3CC,RASGEF1B,CYBC1,SIDT1,PXK,MARCH1,C1orf54,BEND5,RFX5,LRRK2,SELL,SH3BP2,ST6GAL1,LMBRD1,SYPL1,SLC37A2,CYB561A3,TLR4,C9orf85,RFTN2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_500_k5 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.06E-03 1.00E+00 1.13E-02 1.03E-01 33 125 "GRAMD1B,ASPA,CFLAR,MAP7,GUCD1,SNAP91,SGK2,PIPOX,FGFR3,ATP13A4,FUT9,PHYHIPL,GALC,GK,CNDP1,TMEM25,HPS5,NCOA7,C2orf80,MYO6,DRAM2,ELOVL2,SLC6A15,LRRK2,SALL1,HOGA1,KIF21A,SLC15A2,SPP1,PBLD,LRRC8A,TRPS1,VLDLR" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.07E-03 1.00E+00 1.14E-02 1.04E-01 22 74 "PCDH10,DPP10,LDLRAD4,CH25H,CNR1,SLC35F1,NTM,DLX1,FGF13,UBE2E3,FOXF2,PPARGC1A,WIF1,MARK1,HMGCLL1,MAPK10,ROBO1,ANKRD6,ZNF365,SLC15A2,CXXC4,RPRM" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_500 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.09E-03 1.00E+00 1.14E-02 1.04E-01 83 379 "SERPINA3,NDRG2,ADCY5,ANK1,PI16,ATP1A2,MYOM1,ADAM23,NRP2,GPR146,DST,CACNA2D1,CAST,ENTPD2,MFSD4A,CP,GDA,OSBPL3,PLCH2,CNTNAP2,MFAP3L,KBTBD11,CHRDL1,DMPK,CPEB2,DTNA,ABCC9,HIPK3,PCOLCE2,MRVI1,NRN1,FGF1,FHL1,CAP2,SORBS1,FUT9,DKK3,CHL1,GALNT15,DNER,IGSF5,GCNT2,ADAM28,TPPP,GSN,HLF,IFI16,SLC35G1,KCNA1,KCND3,KCNF1,MBP,PFKP,PRKCB,SYTL2,PTHLH,RGS4,TTLL7,SCN7A,STUM,SH3BGR,SH3GL2,FHOD3,SMTN,SLC14A1,RIMS1,SYN2,POPDC3,SEMA4A,TF,TLR4,TNS1,TPM2,RGMB,SYNPO2,PPIL6,RBFOX3,AGMO,PLSCR4,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas GSM538228_500 "B cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5- CD45R+, Peritoneal Cavity, avg-2" "Immgen.org, GSE15907" 3.09E-03 1.00E+00 1.14E-02 1.04E-01 75 337 "SNX30,TXNDC16,BCAR3,FGD2,GAS7,DGKD,TMEFF1,ATP2B1,NRP2,BTK,CACNA1I,CACNA1E,CAMK2D,CD86,CD38,LY86,CDC42BPB,ATRNL1,SIPA1L1,RUBCN,CYBB,MYADM,SIRPA,GUCD1,SLC12A6,EBF1,RASGRP1,FRY,PLXNC1,KCTD3,SRPK3,DENND4A,TLR7,TPPP3,ACSS1,MALT1,RAB30,CECR2,TPPP,ADAMTS6,MAP4K5,IRAK3,TUBB2B,ITGAM,LIFR,MEF2C,AFF1,MYO5A,NAP1L1,NUCB2,PPP3CC,PRKCB,DIRAS2,MARCH1,BEND5,LRRK2,RASA3,ST6GAL1,SLC20A2,LMBRD1,SOX5,STAC2,SLC37A2,TCF4,PSD3,CYB561A3,TPD52,C9orf85,LAT2,EVI5,SIGLEC10,TMEM163,PLD4,PHTF2,SSPN" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_100_k4 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.12E-03 1.00E+00 1.15E-02 1.05E-01 16 48 "CALB1,CRLF1,TMEM59L,CNTNAP2,EMX2,SPSB4,RASL10A,GFRA1,MFSD2A,FRMD5,VWA2,RASGRF2,RET,LRRC4,RPRM,VSNL1" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.15E-03 1.00E+00 1.16E-02 1.06E-01 8 17 "CACNA2D1,VCAN,PDLIM5,REV3L,ERCC6L2,RBFOX2,RGMB,SSBP2" Coexpression Atlas GSM538274_500 "Myeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3" "Immgen.org, GSE15907" 3.15E-03 1.00E+00 1.16E-02 1.06E-01 89 411 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,ABCD2,SEMA7A,APP,SHTN1,CASK,ARHGAP5,CAPRIN2,ZBTB10,CADM3,N4BP2L1,ATP6V0A1,ADAM23,NRP2,CFLAR,CD86,CDH2,UBE2L6,ARHGAP22,CLU,LY86,SLC4A8,GDA,ATRNL1,SDC3,PNPLA8,CTNND1,RASSF2,SIRPA,RABGAP1L,DNM1L,PLXNC1,RASA4,ENO2,EXTL1,ZMYND15,NEK6,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,GYG1,IRAK3,HSF2,DOCK7,INSM1,JAK2,KTN1,VWA5A,ASPRV1,ADAM22,MYO5A,NPR2,PFKFB3,CDK14,CCSER2,PLCL1,SLC22A23,PTAFR,PLEKHB2,ROGDI,RGS10,SEMA6D,SCN4B,ST8SIA1,ARHGEF40,CCDC88A,ITPRID2,SAMSN1,ST5,SULF2,ARHGEF9,TMEM150C,ARC,ATP11A,SLC44A1,DDHD1,TNFRSF1B,SYNPO2,TRPS1,SPIRE1,WNK1,SLC30A4" Coexpression Atlas gudmap_developingGonad_e12.5_ovary_k1_1000 DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.15E-03 1.00E+00 1.16E-02 1.06E-01 34 130 "PWWP2A,KLHL13,RNF182,FUBP1,RUNX1T1,CDH10,HAPLN1,DCT,GSDME,ALKBH8,EDIL3,CHST15,PRMT5,MEX3B,FAM19A2,INSM1,MYCN,NAP1L2,NEFM,TMEM255A,ZFHX4,ROBO2,CSRNP3,SPHKAP,ZKSCAN3,SOX2,SOX5,RBM26,RGL1,KLHL4,CLASP1,ASXL3,TPM1,ZIC3" Coexpression Atlas gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K4 gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K4 Gudmap RNAseq 3.15E-03 1.00E+00 1.16E-02 1.06E-01 34 130 "DOC2A,NOL4,CALB1,CRLF1,SLIT2,TMEM59L,DUSP9,EMX2,ERBB4,FGF12,RASL10A,GJB1,L1CAM,KITLG,NEFM,NELL1,VWA2,MAPK4,RASGRF2,RET,NUDT11,GLDN,PRR5L,SCG5,SLIT1,RAP1GAP2,NKAIN2,TMEM150C,SYT5,RPRM,VSNL1,ANKS1B,TMEM178A,AP3B2" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_200 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.18E-03 1.00E+00 1.17E-02 1.07E-01 42 169 "FAM135A,MYOM1,BCHE,NRP2,LDLRAD4,CACNA2D1,AKAP5,EDIL3,EPHB1,ETV1,FOXF2,PNMA2,DKK3,MEGF10,GABRA4,CHL1,GABRB1,LYVE1,PCDH11X,RAB40B,RAPGEF4,IFI16,NAP1L2,HCN1,PCDH8,RGS4,ZFHX4,SPHKAP,PEG10,NPAS3,C11orf87,COBL,ZFPM2,ERCC6L2,RGMB,SYNPO2,TRPS1,FAM13C,ACTR3B,MSRB3,NETO1,SOCS4" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000 kidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.19E-03 1.00E+00 1.17E-02 1.07E-01 157 780 "ACADM,NDRG2,OSBPL6,ADGRF5,SPARCL1,C6orf89,DDO,APP,ASPA,ATP1A1,SLC4A4,ALDH7A1,MYOM1,SEC11C,CFLAR,LDHD,CA4,CA12,CACNA2D1,CACNB2,CALB1,MAP7,CLDN10,DCLK1,CDO1,ADGRG1,NDST3,SLC22A6,CLU,TPP1,CLTB,ABCG2,ARHGEF6,CP,RGS6,CTH,ARHGAP24,ACY3,DGKB,DBI,FAM107B,CCDC3,DMD,ABCC9,EBF1,EDIL3,EDN1,EDNRA,EDNRB,SGK2,HEYL,FRY,FAM13A,AASS,CALCRL,RCAN2,ENPP6,EPS8,ERBB4,ETV1,PIPOX,FABP7,EFEMP1,DLC1,FGF1,FHL1,CAP2,FOLH1,FUT9,STARD10,GATM,ALDH1L1,TUBA8,GHR,PPARGC1A,GK,GNAO1,GPM6A,RAPGEF4,GSTT2,GUCY1A2,GUCY1A1,GUCY1B1,HLF,TCEAL6,HSPA1L,SCIN,SLC6A17,LRRTM3,KCNJ10,KCNJ16,KHK,C2orf80,AQP11,MEF2C,MYO6,NFE2L2,NFIX,DDR2,IGSF11,PAH,PCDH9,PDE1A,PDE3A,PDE4D,ENPP2,PGAM2,ABCB1,SERPINE2,SERPINI1,PLCL1,FXYD1,PLTP,SEPT4,MINDY2,PPP1R1A,PRODH,RELN,SYTL2,PTH1R,PTPRB,ACSM5,PLEKHB2,FIGN,SUGCT,RERGL,LRRK2,SCN2A,STUM,SLC4A3,SLC2A5,SLC8A1,SLC12A2,SLC15A2,EFHD1,CPEB4,LIMCH1,LMBRD1,SPP1,TEX2,NXT2,ADHFE1,PLCB1,SLC19A3,AHCYL2,TLR4,HEY2,TNS1,TPM2,TRPC1,PPIL6,CA14,UGT8,VLDLR,SLC13A3,KCNAB1,RGS7BP" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k1_200 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.23E-03 1.00E+00 1.19E-02 1.08E-01 19 61 "USP31,TAOK1,NRP2,CACNA2D1,VCAN,DLC1,GFRA1,PCDH11X,MMP16,NFIA,PRRX1,FAT3,NAPB,SOX5,HHIP,ERCC6L2,RBFOX2,RGMB,TRPS1" Coexpression Atlas Lungmap Mouse Lung PND1 Pericyte Subtype All subclasses Lungmap Mouse Lung PND1 Pericyte Subtype All subclasses Lungmap CCHMC 3.23E-03 1.00E+00 1.19E-02 1.08E-01 45 184 "SYN3,NDRG2,SPARCL1,APP,ATP1A2,CD81,SEPT7,CDH2,ARHGEF6,CST3,ZEB2,EBF1,EDNRA,HEYL,RASGRP2,RASL12,DKK3,HIGD1B,HTATSF1,GNAS,FERMT2,GUCY1A1,GUCY1B1,ELOVL5,KCNK3,LIMS1,MAPT,MATN2,CCDC80,NFIA,ENPP2,FXYD1,PCDH18,SEPT4,NKAIN4,EMID1,PEAR1,BTBD3,PDZD2,TACC1,PJA1,TNS1,CADM1,TUBA1A,TMEM178A" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_k4_500 kidney_e13.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.23E-03 1.00E+00 1.19E-02 1.08E-01 35 135 "VCAN,GSDME,SRGAP3,AFF2,IGSF5,FREM1,HAS2,NEGR1,NEFM,NPY,NOVA1,OLA1,FAT3,MDGA2,SPDL1,PTX3,TSPY26P,RMI1,FAM19A1,CNKSR2,SLC4A3,GKAP1,CMTR2,ADAMTS17,CUX2,PCDHB9,PCDHB3,ITGB3BP,BHLHB9,STXBP4,TRPS1,ZNF708,STOX2,MRPL47,NETO2" Coexpression Atlas gudmap_developingGonad_e12.5_testes_1000 DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.24E-03 1.00E+00 1.19E-02 1.08E-01 164 819 "ABCF1,ACLY,ARID1A,ADD1,PWWP2A,NR0B1,AK2,TAOK1,AMH,OGT,SEMA7A,LCORL,EPB41L5,APLP1,DGKZ,DGKD,CASK,ARHGDIG,NUMB,DDX3Y,ATM,RNF182,BACH1,ADGRB2,ST3GAL5,MYRF,MMD2,BTRC,DDR1,CALM1,CAMK2G,RUNX1T1,CBLN1,CCNT1,ARHGEF1,CDC42,ADGRG1,CLU,QKI,NIPBL,COL9A2,COL9A3,RBM39,RNF14,CTNND1,PUM1,ARHGAP32,FGFR1OP2,MATR3,DAPK1,DAPK3,DBI,DBN1,DCT,DCTN1,COPS7A,GSDME,ALKBH8,RCAN1,DTNA,DNM1L,EDNRA,MBNL2,PLXNC1,ELAVL2,EPB41L2,PTK2B,PRMT5,SEC24B,KIAA1109,FGFR1,FYN,NEK6,GART,AHDC1,CSDC2,TCERG1,OS9,GPM6B,LPAR4,GPR37,GRB10,GUCY1B1,MAEL,SMAP1,TUBB2B,JAK1,KCNH1,KIF2A,KLC1,TTYH2,CHIC1,MEF2C,KITLG,SESN3,MYO7A,NASP,NCAM1,NNAT,PAK3,PDGFRA,OLA1,SEMA5B,PIK3R1,ZNF655,PCDH18,PLTP,RC3H2,EXOSC10,SH3KBP1,PRKACB,MAPK8,PTPRD,PTPRE,TMEM255A,UBR7,ROBO2,MEG3,ATXN2,SFPQ,SUPT20H,ARX,SEC31A,SCMH1,ZKSCAN3,SMARCA4,SNRPN,SON,SOX2,SOX5,ZCCHC24,CAND2,RBM26,SPART,TROVE2,JMJD6,SYNE2,PJA1,FBXW11,KLHL4,SIN3B,PUM2,LEFTY2,HHIP,ASXL3,TMPO,TNS1,RBFOX2,TPM1,NR2C2,ZMYND8,KCNE5,SSBP2,TST,USP1,ZIC3,ZFAND5,INTS3,STOX2,ADAMTS9,PCBP4,RTN4,VANGL2,ADAMTS10" Coexpression Atlas GSM854315_500 "Myeloid Cells, MF.169+11chi.SLN, CD11b+ CD169+ CD11chigh, Lymph Node, avg-2" "Immgen.org, GSE15907" 3.26E-03 1.00E+00 1.19E-02 1.09E-01 84 385 "CPNE2,FMNL2,ALCAM,FGD2,APP,SHTN1,CADM3,ADAM23,ST3GAL5,C1QC,DDR1,CD86,B4GALT6,LY86,FAM149A,GDA,CSF1R,CSF2RA,CST3,SDC3,CTNND1,CTNND2,CX3CR1,CYBB,DOCK4,MYADM,SIRPA,DBN1,DSCAM,PLXNC1,RASA4,PLEKHO1,EPS8,IGSF6,SIRPB1,FCGR1A,FCGR3A,FCGRT,OLFM1,FGR,GATM,GCNT2,GFRA2,RAB30,ADAP1,GSN,IRF8,IFI16,LRRC25,DOCK7,ITGAM,KIT,LIFR,ADAM11,MYO9A,P2RY13,NCF2,CLEC9A,CDK14,PLTP,PILRA,RASGEF1B,PTAFR,MARCH1,RAB3IL1,PID1,C1orf54,ROGDI,SNX22,ACER3,LRRK2,KCNIP3,RTN1,CCDC88A,RGL1,SULF2,SEPT3,KIAA0930,TIAM1,TPD52,TRIO,SIGLEC10,PLD4,NLRP3" Coexpression Atlas facebase_RNAseq_e9.5_OlfPlac_2500_K3 facebase_RNAseq_e9.5_OlfPlac_2500_K3 Gudmap RNAseq 3.31E-03 1.00E+00 1.21E-02 1.10E-01 230 1188 "ACLY,TMCC3,AXIN2,KIAA1211,AP1B1,KLHL13,PCDH19,ZNF687,DOC2A,TRMT9B,ANK3,FGD2,MYH7B,DGKZ,NT5C3B,TMEFF1,ARRB2,ATM,BCHE,BLM,ZNF599,PROM1,BMP7,WASF1,CA4,CA12,CACNB2,HAP1,PTBP2,BRSK2,MTMR7,CBFA2T2,ARHGEF2,CDH2,LRWD1,TBRG4,CACNA2D2,ADGRG1,CBARP,KIAA1549L,MYL6B,TMEM59L,TJP2,FAM19A5,HOMER3,CNTFR,PCYT1B,SLC4A7,BAG4,ZNF385A,HAPLN1,CNTNAP2,PLXNA4,FAM169A,GREB1,KATNAL2,AIF1L,MED24,DLG3,USP3,CDON,DTNA,DUSP9,FARSB,E2F5,TSPAN5,RBM12,YAF2,EFNB3,EIF4G1,ELAVL2,RGS17,EMX2,EPB41,ANKRD13B,EPS8,ETV1,EYA1,REEP2,TUBB4A,CEP78,POLR1B,SPSB4,FGF12,CAMSAP1,FHL1,SEMA6C,SYT3,NELFCD,POMT1,TMEM107,CINP,PDLIM5,KHDRBS3,FUT9,PHYHIPL,MTHFD2,GART,WASF3,TCERG1,DBF4,GLI2,GLRB,TOX3,GLUL,STARD3,KIAA1958,GNG3,PSRC1,GPD2,B4GALNT4,CECR2,GRIA4,RFFL,ZNF496,RNF165,PSIP1,FAM107A,FAM222A,HAS2,FRMD5,ARHGAP19,HSF2,LRRC75A,HSP90AA1,SHISAL1,TUBB2B,METTL21A,KCNH2,KIF5C,KIT,MAOB,AQP11,ADAM11,MEIS1,MEST,KCTD6,AFDN,MSI1,TAGLN3,MXI1,MYCN,NAP1L1,NASP,RCOR2,NNAT,ODF2,PDE3B,PDPK1,NOMO2,SNX10,RETREG1,PKM,GPSM2,EPN1,PLP1,SLC25A23,PSAT1,PPP5C,PRODH,GDPD1,LAMA1,UHRF1BP1,ELOVL2,ZIK1,PTPN13,EML5,NKAIN1,RAB3A,CCDC40,ZMAT4,DPF2,FIGN,RFX3,NUDT11,RAVER2,GSTCD,PRR5L,ACER3,RPS6KA2,LGR4,HUNK,RTN1,TRAPPC13,SALL1,MAPK12,SATB1,SOX6,KIF21A,ST6GAL1,CCDC92,PKNOX2,IFT122,KIF21B,SOX11,SPTB,KANK1,ANKRD28,MMS19,TCF7,DOCK9,SIRT1,ITGB3BP,HEY1,HEY2,CA14,HIRA,CADM1,AMOT,DNAJC12,SLAIN1,FAM181B,USP1,VAV2,NSD2,KLC2,ZFP41,TFIP11,MEIS3,DHX33,SLC38A1,RGMA,TUBA1A,ADAMTS9,NAV2,PCBP4,WNK2,FZD3,TTC7A,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k5 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.35E-03 1.00E+00 1.22E-02 1.12E-01 21 70 "LDLRAD4,CDH2,SLIT2,NCOR1,EDIL3,ETV1,FOXF2,PNMA2,MEGF10,GABRA4,GABRB1,RAB40B,RAPGEF4,IFI16,NAP1L2,PCDH8,RGS4,ZFHX4,SPHKAP,NPAS3,MTCL1" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_200 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.35E-03 1.00E+00 1.23E-02 1.12E-01 14 40 "RGN,SLC16A4,CDH10,DCT,MTSS1L,CAMKK2,PPARGC1A,GPR37,PDGFRA,RBBP8,REV3L,ST8SIA1,SMOC1,ZFPM2" Coexpression Atlas facebase_RNAseq_e8.5_ParaxMesoderm_2500_K1 facebase_RNAseq_e8.5_ParaxMesoderm_2500_K1 Gudmap RNAseq 3.37E-03 1.00E+00 1.23E-02 1.12E-01 12 32 "NOL4,NRXN3,CNR1,IGDCC3,AFF2,GRIK2,NOVA2,ELOVL2,SLIT1,WSCD1,ZBTB16,DPYSL5" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.37E-03 1.00E+00 1.23E-02 1.12E-01 12 32 "PCDH10,CRLF1,TMEM132C,FOXF2,SGIP1,GABRB1,WIF1,PRRX1,ZFHX4,PRR5L,TAC1,UNC5D" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Proliferative Endothelial_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Proliferative Endothelial_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.39E-03 1.00E+00 1.24E-02 1.13E-01 57 245 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,ABCG2,CNN3,HAPLN1,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,LPAR6,CALCRL,FAM198B,FLT1,PCDH17,LYVE1,LPAR4,STMN2,GRB10,ICA1,KIT,STMN1,LMO2,MEF2C,MEIS2,MEST,KITLG,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TMPO,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Proliferative Endothelial_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Proliferative Endothelial_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 3.39E-03 1.00E+00 1.24E-02 1.13E-01 57 245 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,ABCG2,CNN3,HAPLN1,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,LPAR6,CALCRL,FAM198B,FLT1,PCDH17,LYVE1,LPAR4,STMN2,GRB10,ICA1,KIT,STMN1,LMO2,MEF2C,MEIS2,MEST,KITLG,CD200,CLEC9A,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TMPO,TUBA1A" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k3_500 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.40E-03 1.00E+00 1.24E-02 1.13E-01 13 36 "TTYH1,MTA3,USP28,SHTN1,ALDH7A1,CPEB2,ATP8A1,MOV10,PTPRE,NUDT11,KIF21A,BEX4,TPD52" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k1 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 3.40E-03 1.00E+00 1.24E-02 1.13E-01 13 36 "SORCS1,EPHA5,EYA1,SGIP1,DACH2,RSPO2,NAP1L2,GPR85,TRHDE,ROBO1,SCN3A,NPAS3,PCDHB3" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.41E-03 1.00E+00 1.24E-02 1.13E-01 64 281 "METAP1D,ADD3,AXIN2,AMPH,OGT,LRCH2,LGR5,CDK10,SEMA4G,PDE8B,INSYN2B,CACNA1D,FEZ1,CTH,GREB1,MAGI2,SACS,SRGAP3,DOCK2,RASGRP1,NRN1,FGF11,KHDRBS3,GABRB1,NEU3,SESN1,GRIK3,PLD5,IL6ST,DIPK1A,SLC35G1,ARHGAP12,GPR155,MAOB,SESN3,MTR,NPR2,ENPP2,CDK14,MAPK9,GDPD1,CNNM2,GDPD2,PTGR2,PRCD,TNFRSF19,STUM,ABLIM3,SCMH1,KDM3A,ARHGAP26,LHPP,ADAMTS17,FNDC9,RPGRIP1L,TCF12,GZF1,DAAM2,DCBLD1,LYPD6,REEP1,TMEM178A,SNX14,FRMD6" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_1000 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.47E-03 1.00E+00 1.26E-02 1.15E-01 39 155 "KDM5D,AMH,GAS7,CADPS,DDX3Y,CLU,MAGED1,SCRN1,DTNA,MAMLD1,MRO,PLXNC1,SORBS3,EPS8,ERBB4,FAM198B,PTK2B,FGF13,FYN,GATM,PPARGC1A,GPM6B,GPR37,KCNH1,MOV10,PAK3,PGAM2,SERPINE2,RASGEF1B,PRKCB,MASP1,ROBO1,GLDN,MRAS,DOCK10,TNIK,THRA,BEX4,ADAMTS9" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k4_500 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.47E-03 1.00E+00 1.26E-02 1.15E-01 39 155 "ACTN1,NDRG2,SPARCL1,ALDH7A1,MYOM1,CACNB2,DCLK1,LGI1,NDST3,NTM,CCDC3,DMD,EDIL3,EDNRA,HEYL,CERCAM,ABCA8,FHL1,CAP2,IGSF5,HSPA1L,PLD5,SLC6A17,MEF2C,CTNNA3,NTRK3,PCSK2,RELN,SYTL2,FIGN,RERGL,SALL1,SH3BGR,SLC4A3,HEY2,TPM2,TRPC3,KCNAB1,RGS7BP" Coexpression Atlas GSM605787_500 "gamma delta T cells, Tgd.vg2+.Sp, TCRd+ Vg2+ CD44-, Spleen, avg-3" "Immgen.org, GSE15907" 3.51E-03 1.00E+00 1.27E-02 1.16E-01 84 386 "ACTN1,NDRG2,ADD1,ADD3,AXIN2,ESYT2,USP28,ATP1B3,BAIAP3,LDLRAD4,CLDN10,CHN2,IPCEF1,HDAC9,RIPOR2,HDAC4,TOX,SPOCK2,PITPNC1,KBTBD11,RASGRP1,LPAR6,RASGRP2,KAT8,FGF13,MEX3B,NSG2,SARAF,TRAF3IP2,B4GALNT1,RAPGEF6,ARPP21,SESN1,RAPGEF4,PADI2,BACH2,ZDHHC15,AGFG1,IL6ST,ITPKB,JAK1,KIT,HECTD2,SESN3,P2RX7,ZNF827,PDE3B,PDE4D,ABCB1,SERPINI1,JAKMIP1,SLC25A23,SH3KBP1,PRKCZ,SIDT1,CEP97,BEND5,TSPY26P,PRR5L,WLS,SATB1,SELL,RASA3,FAM102A,ST6GAL1,ST8SIA1,DZIP1,SLC14A1,TET1,TNIK,KIF21B,SP4,DNAJC9,TCF7,TCF12,KCTD2,TRIO,RUNDC3B,SSBP2,TTC3,UBE2H,SLAIN1,PMEPA1,SPATA13" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500 dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.51E-03 1.00E+00 1.27E-02 1.16E-01 33 126 "ARHGAP20,TMEM108,MYRF,CBLN1,CNTFR,TENM4,MICAL2,ATRNL1,VCAN,DNM1,EDNRA,SEMA3D,FABP7,FLNC,FREM1,CSDC2,GHR,GLI2,GUCY1A1,MEIS1,NCAM1,NME4,PDGFRA,PRRX1,PTN,RADX,ROBO2,MEG3,PKNOX2,PALLD,ASXL3,TMEFF2,ST8SIA2" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_500_k5 DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.51E-03 1.00E+00 1.27E-02 1.16E-01 26 93 "ADRB2,GPR146,LDLRAD4,LDB2,CD86,CSF1R,IGSF6,F8,FCGR1A,FYB1,GATM,GGTA1P,LYVE1,NCKAP1L,PIK3AP1,TM6SF1,MSR1,P2RY13,PRR5L,SLA,TEK,TF,TLR4,NPL,VAV1,FAM13C" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_k4_1000 kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.53E-03 1.00E+00 1.28E-02 1.17E-01 52 220 "RALGAPA1,USP31,SPARCL1,AMPD3,NRP2,MTMR2,IL33,CA8,CH25H,CBLN1,FMNL3,CHN2,TAOK2,ABCG1,PLXNA4,ELMO1,SEMA3D,TMTC1,LPAR6,ATP8A1,KIAA1109,GALNT15,LPAR4,IRAK3,IGF1,STXBP5,INSYN2,SMAD1,TM6SF1,PFKFB3,PMP22,RASGEF1B,PROX1,MAPK12,SCN2A,FNIP1,MAGI3,EPN2,SMTN,SLCO1A2,LIMCH1,ZHX3,C3orf70,ANKRD28,ROBO3,KLHL4,VWA3A,TCF4,DOCK9,TRPC3,UCHL1,AGMO" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_500 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500 FaceBase_RNAseq 3.57E-03 1.00E+00 1.29E-02 1.18E-01 104 493 "SLITRK1,DISP3,ANK1,PHYHD1,APOC2,USP37,SPTBN4,ADAM23,ZNF599,BMPR1B,LDLRAD4,CACNA2D1,DIRAS1,CDK11B,LRBA,KCNAB3,ADGRG1,SRSF11,FAM149A,COL9A1,IGDCC3,CRYBB1,CRYM,PLCH2,DZIP3,PHF14,ST18,SPOCK2,JAKMIP2,GSDME,DDX46,DLX1,SHANK1,CASP8AP2,DUSP9,SYT15,TMEM35A,EPB41,NSRP1,TMEM132C,AFF2,ZCCHC17,SMC2,B3GAT1,TMEM8B,ZNF638,MAP7D2,ADAP1,CECR2,MFSD2A,RABL2A,USP51,KNDC1,LRRCC1,LIX1,KCNJ5,KIF5C,KIT,TM6SF1,MOBP,RSPO2,NASP,NRGN,ODF2,PDE1A,PRRX1,MAGEL2,POU6F1,CRLS1,DIRAS2,MDGA2,STRC,RBBP8,ZMAT4,DUSP15,DGLUCY,SFPQ,DOCK10,FHOD3,ST6GAL1,CNKSR2,NLGN1,PREX2,PEX26,DHX30,CCDC88A,LIMCH1,BDP1,SOX11,UHRF1BP1L,NPAS3,C11orf87,ROBO3,SATB2,ITGB3BP,ASXL3,TMOD1,SYNPO2,TRPS1,CA14,USP1,ZNF184,DNAH10,MRPL47" Coexpression Atlas GSM403988_500 "CD positive, CD19 Control, 19+ 4- 8-, Spleen, avg-6" "Immgen.org, GSE15907" 3.62E-03 1.00E+00 1.31E-02 1.19E-01 75 339 "SNX30,ZNF608,TXNDC16,BCAR3,CARNS1,FGD2,INSYN2B,ATP6V0A1,BCL7A,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD86,CD38,LY86,CNN3,SLC4A7,RUBCN,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,PLXNC1,SRPK3,DENND4A,TLR7,HVCN1,MALT1,RAB30,DCLK2,EML4,CECR2,RAPGEF4,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,KTN1,LMO2,PIK3AP1,GPR155,MEF2C,CD200,MYO5A,PPP3CA,PPP3CC,RASGEF1B,PRKCB,SIDT1,PXK,MARCH1,BEND5,LRRK2,SELL,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,TCF4,CYB561A3,TLR4,C9orf85,VAV2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.62E-03 1.00E+00 1.31E-02 1.19E-01 75 339 "RALGAPA1,ABCF1,OGT,ANK3,PKP4,APC,DGKD,PHYHD1,BMP7,CANX,CLCN3,RBM39,UBXN2A,FGFR1OP2,ARHGAP24,DDX46,ARNT2,HIPK3,SEMA3D,EIF5,SRPK3,EIF1,MED12L,SUCO,SYNCRIP,SMC2,PDLIM5,AHCYL1,IQGAP2,GFRA1,PPARGC1A,CNTRL,GRB10,ICA1,TUBB2B,KIF5C,KITLG,NASP,NEK1,CNOT4,OCRL,PIK3C2A,PSAT1,MBOAT7,KANSL1,PKN2,RASGRF2,DPF2,REV3L,CLIP1,SFPQ,ASRGL1,RUFY2,SCMH1,LIMCH1,STX1A,PRRC2C,PJA1,DNMBP,CAMSAP2,WWC1,TBL1X,MGRN1,NSD1,ERCC6L2,R3HDM1,RGMB,TRIO,SSBP2,VLDLR,ZNF23,ZNF24,FMN2,FIP1L1,NUP214" Coexpression Atlas GSM777019_500 "B cells, B.Fo.LN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-2" "Immgen.org, GSE15907" 3.62E-03 1.00E+00 1.31E-02 1.19E-01 75 339 "SNX30,ADRB2,ZNF608,TXNDC16,BCAR3,BIN1,FGD2,ATP6V0A1,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,CSNK1G3,KIAA0040,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,ELMSAN1,SLC12A6,EBF1,SNX29,FRY,SRPK3,TLR7,HVCN1,TRAF3IP2,RAB30,DCLK2,CECR2,RAPGEF4,IRAK3,BACH2,IRF8,IL12A,DIPK1A,LMO2,PIK3AP1,MEF2C,CD200,NCF2,PPP3CC,RASGEF1B,SIDT1,PXK,MARCH1,BEND5,RFX5,RPL38,LRRK2,SELL,SH3BP2,ST6GAL1,SLC4A3,LMBRD1,ARHGAP26,STAC2,SYPL1,MGRN1,CYB561A3,TLR4,C9orf85,RFTN2,VAV2,LAT2,SIGLEC10,TMEM163,CAB39L,PLD4" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.63E-03 1.00E+00 1.31E-02 1.19E-01 24 84 "ABAT,CDC14B,ATP2B1,CDH2,SRGAP3,PLXNC1,F3,FAM198B,AFF2,ZMAT1,ADGRA3,GPM6B,GPR37,HSPA1L,PTPN13,ROBO1,TMEM206,DOCK10,ST6GAL1,ST8SIA1,SMOC1,OBSL1,ZFPM2,WNK3" Coexpression Atlas gudmap_kidney_P2_CapMes_Crym_k3_1000 kidney_P2_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 3.64E-03 1.00E+00 1.31E-02 1.20E-01 20 66 "MTUS1,TXNDC16,ALCAM,ADAM23,BCHE,IL33,BOC,SPOCK2,ARRDC4,EXTL2,GLRB,KCNMA1,MMP16,FXYD6,NFIX,PENK,EPDR1,NPAS3,SULF2,TPM2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Proliferative Immature MyoFibroblast_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Proliferative Immature MyoFibroblast_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 3.68E-03 1.00E+00 1.32E-02 1.21E-01 58 251 "NDRG2,SPARCL1,LTBP4,ALDH7A1,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,SNCAIP,VCAN,DOCK4,ZEB2,EDNRA,EDNRB,PCOLCE2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,KCNK3,NCAM1,NNAT,DDR2,PBX1,PDGFRA,SERPINE2,FTO,SMOX,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,PTH1R,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,CBX5,ZNF32,TUBA1A,ADAMTS10" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Proliferative Immature MyoFibroblast_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Proliferative Immature MyoFibroblast_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 3.68E-03 1.00E+00 1.32E-02 1.21E-01 58 251 "NDRG2,SPARCL1,LTBP4,ALDH7A1,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,SNCAIP,VCAN,DOCK4,ZEB2,EDNRA,EDNRB,PCOLCE2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,KCNK3,NCAM1,NNAT,DDR2,PBX1,PDGFRA,SERPINE2,FTO,SMOX,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,PTH1R,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,CBX5,ZNF32,TUBA1A,ADAMTS10" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_100 dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 3.68E-03 1.00E+00 1.32E-02 1.21E-01 22 75 "CALB1,PLXNA4,DOCK4,DRP2,PLXNC1,EMX2,NRN1,GABRA4,FREM1,PCDH11X,GUCY1A1,KCND2,KLHL23,MATN2,KITLG,NEFM,PDE1A,PDGFRA,PCDH18,ADGRL3,ACTR6,LYPD6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k4 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.68E-03 1.00E+00 1.32E-02 1.21E-01 22 75 "PCDH10,SYT13,INSYN2B,RUNX1T1,DCLK1,CRLF1,NTM,DLX1,TMEM132C,SGIP1,GABRB1,GNG4,WIF1,MYH3,ZFHX4,PRR5L,SALL1,SLC15A2,LIMCH1,SOX11,TAC1,KCNAB1" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_500_k5 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 3.71E-03 1.00E+00 1.33E-02 1.21E-01 17 53 "PCDH19,DOC2A,BMP7,SLC32A1,KIAA0040,GREB1,DUSP9,SPSB4,B4GALNT4,PLXNB1,LAMA1,NKAIN1,FAM184A,EMID1,TMEM150C,CA14,TMEM178A" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_500 dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 3.71E-03 1.00E+00 1.33E-02 1.21E-01 17 53 "ASPHD1,CLIP3,TUBB4A,NSG1,PCSK1N,GNG3,CELF3,TAGLN3,NNAT,PCBP3,SLC10A4,GDAP1L1,PRPH,SST,TMEFF2,MTCH1,MVB12B" Coexpression Atlas Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K4 FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 3.76E-03 1.00E+00 1.35E-02 1.23E-01 56 241 "EMILIN3,ACTN2,ADCY2,ARHGAP20,ADGRB2,C1QC,CACNA1G,LDLRAD4,CACNA2D1,REPS2,KCNAB3,CDO1,CRLF1,ANKRD44,CSF1R,VCAN,CCDC3,DLG2,USP3,SNX29,RASA4,ELN,LRRC17,FCGRT,TESK2,TRIM16,TMEM151A,FYB1,TMEM8B,ZNF276,WIF1,SYNPO,IL11RA,ITPKB,VWA5A,TCEAL5,CNTN3,PDE1A,PLCL1,NXPH1,PRKAR1B,ZCWPW1,ZMAT4,MYH14,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC1A2,ADGRL3,PHF24,FAM189A1,HHIP,PMEPA1,CADM2,PCDH15" Coexpression Atlas gudmap_kidney_e13.5_Podocyte_MafB_k1_100 kidney_e13.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 3.77E-03 1.00E+00 1.35E-02 1.23E-01 7 14 "VCAN,IGSF5,FREM1,NPY,FAT3,MDGA2,CUX2" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200 dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 3.81E-03 1.00E+00 1.37E-02 1.25E-01 37 146 "GRAMD1B,ARHGAP20,LTBP4,ADAM23,CACNA2D1,CBLN1,SCARB1,SLIT2,CLU,VCAN,EDNRA,EGFR,PLXNC1,LRRC17,NRN1,IQGAP2,GFRA2,FREM1,GPM6B,GUCY1A1,GUCY1B1,LAMA2,MATN2,PAK3,PDE1A,PDGFRA,PCDH18,PLTP,FAT3,PTCH1,TMEM255A,ROBO2,SMOC1,ADGRL3,HHIP,VSNL1,STOX2" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 3.82E-03 1.00E+00 1.37E-02 1.25E-01 9 21 "CSMD3,NDRG2,CACNA1B,CACNA1E,LSAMP,PENK,SCN2A,FAM19A1,TNR" Coexpression Atlas GSM399373_500 "alpha beta T cells, T.4SP24int.Th, 4+ 8- TCRhi 24int, Thymus, avg-3" "Immgen.org, GSE15907" 3.83E-03 1.00E+00 1.37E-02 1.25E-01 72 324 "ACTN1,NDRG2,ADCY6,AXIN2,ARHGAP20,PITPNM2,DGKZ,SFMBT2,GPR146,SYNJ2,FMNL3,CD81,CNN3,LRIG1,SIPA1L1,PPP1R16B,TOX,KBTBD11,DLG4,CDON,RASGRP1,TNK2,TMEM35A,TLR7,TMEM164,CAP2,TACC2,NSG2,FYN,CHL1,KCNMB4,RAPGEF4,GSN,ADAMTS6,BACH2,ZDHHC15,ITPKB,KCNH2,STMN1,SESN3,ZNF827,PDE4D,TMIE,SLC25A23,SPATA6,PACSIN1,PPM1B,SYTL2,ZSCAN2,BEND5,RGS3,RGS10,RAVER2,SATB1,IL17RB,ZNF821,GALNT10,FAM102A,ST6GAL1,ST8SIA1,DZIP1,TET1,TNIK,CAND2,PJA1,TCF7,TGFBR3,BHLHB9,RUNDC3B,SSBP2,TTC3,TUBA1A" Coexpression Atlas GSM538201_500 "B cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 3.83E-03 1.00E+00 1.37E-02 1.25E-01 76 345 "ADD3,SNX30,ADRB2,ZNF608,TXNDC16,BCAR3,FGD2,DGKD,ATP6V0A1,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,SLC4A7,CSNK1G3,RUBCN,USP6NL,CYBB,HDAC9,RIPOR2,ARHGAP24,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,TLR7,HVCN1,MALT1,RAB30,DCLK2,EML4,CECR2,RAPGEF4,ADAMTS6,MAP4K5,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,MEF2C,CD200,MYO5A,NCF2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,SIDT1,PXK,MARCH1,BEND5,RFX5,LRRK2,SELL,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,CYB561A3,TLR4,C9orf85,VAV2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K2 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 3.94E-03 1.00E+00 1.41E-02 1.28E-01 40 161 "ERMN,TMEM108,TTLL9,CA12,INA,ARHGEF1,LRRFIP1,CCPG1,LRRC3B,SEZ6,NCALD,CEND1,TUBB4A,FGF11,NOP56,COQ5,SALL3,CSDC2,GRIK5,HSP90AA1,SHISAL1,CDH20,CPNE9,CCDC80,ADAM22,IGSF11,SNX10,PMP22,MAGEL2,NXPH1,NKAIN4,RELN,MYH14,STK32B,YJEFN3,SALL1,NTNG1,SNRPN,C11orf87,CA10" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgM_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.95E-03 1.00E+00 1.41E-02 1.29E-01 19 62 "SEPT7,CDO1,IGDCC3,NECTIN3,TOX,DCC,EFNB3,EN2,ADGRV1,FAM198B,FABP7,MEST,MSI1,PLCL1,PTPRO,ARID4A,RFX4,SOX2,SULF2" Coexpression Atlas GSM538315_500 "NK cells, NK.Sp, NK1.1+, Spleen, avg-3" "Immgen.org, GSE15907" 3.98E-03 1.00E+00 1.42E-02 1.30E-01 88 409 "AS3MT,RNF157,GRAMD1B,ADORA2A,KCNAB2,GAS7,CDC14B,ATP1B3,BAIAP3,CAMK2G,CHN2,ABCG2,OSBPL3,CX3CR1,RIPOR2,TOX,PITPNC1,ZEB2,TIAM2,SRGAP3,DOCK2,PDCD6IP,FAM78B,TNK2,DENND4A,RASL12,EYA1,ST3GAL6,FER,OLFM1,FYN,B4GALNT1,MALT1,GP1BB,PADI2,KLF12,IRF8,ITGAM,JAK1,KIT,KLRC2,KLRC3,PIK3AP1,TM6SF1,STK32C,MYO6,PDE2A,PFKP,CDK14,ABCB1,SSH1,PIK3R1,PPP3CC,SYTL2,SIDT1,OXR1,PRR5L,KCNIP3,SATB1,PEAR1,SELL,RASA3,FAM102A,ELMO2,SMARCD3,TNIK,KIF21B,ARHGAP26,KIF1B,RAP1GAP2,ST5,SULF2,SYT11,SEMA4A,KLHL4,TCF7,AKNA,GPRIN3,FRYL,PIK3R5,TRIO,RUNDC3B,MICAL1,LAT2,TMEM163,PLSCR4,MARCH8,SPATA13" Coexpression Atlas Lungmap Mouse Lung E16.5 Myofibroblast Subtype Smooth Muscle-like Myofibroblast Lungmap Mouse Lung E16.5 Myofibroblast Subtype Smooth Muscle-like Myofibroblast Lungmap CCHMC 4.07E-03 1.00E+00 1.45E-02 1.32E-01 87 404 "SDE2,CDC7,USP35,LCORL,TMEFF1,ZSCAN18,CHRD,ATP1A2,CAMK2D,RUNX1T1,DCLK1,VAX2,QKI,AKAP6,ABI3BP,NRG2,FAM171B,RNF14,CLIP3,LRIG1,DOCK4,GPRASP1,DAPK1,DMD,SHANK1,CASP8AP2,TSPAN5,YAF2,KMT5B,LRRC17,SPEG,MRPL10,MRVI1,FCGRT,FOXF2,NPTN,MEGF10,DHRS4,MSL3,GPER1,GRB10,PARD3B,GSN,BVES,HPSE2,NKD1,KCNK3,KCNMA1,SAMD14,DDR2,TBC1D25,PALM,PDE4D,PIRT,CYTL1,PFKFB3,SERPINE2,PLEC,HMGCLL1,PPM1B,PRKAR1B,PSD,GON4L,PTPRD,REV3L,RGS4,RIC8B,DCUN1D2,FBXW7,ADAL,CLIP1,ATXN1,PALLD,FAM126B,IZUMO4,KDM4C,SPTAN1,ITPRID2,DNAJC9,ANKRD12,KAT6B,TPM1,TRO,TRPS1,UBE2H,MFF,JMJD1C" Coexpression Atlas GSM538252_500 "Myeloid Cells, DC.8+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3" "Immgen.org, GSE15907" 4.08E-03 1.00E+00 1.45E-02 1.32E-01 90 420 "CPNE2,FMNL2,ADCY6,RNF150,ADRB2,ALCAM,FGD2,APP,SHTN1,CASK,TMEFF1,ARHGAP5,ADAM23,ST3GAL5,BTK,CACNA1E,SPAG9,CD86,SCARB1,CD81,LY86,FAM149A,SLC4A8,ZNF385A,CDC42BPB,CSF2RA,OSBPL3,CST3,SDC3,CTNND1,HDAC9,DBN1,SRGAP3,CDON,ARRDC4,PLXNC1,RASA4,PLEKHO1,EPS8,FCGRT,OLFM1,ZMYND15,GALC,NEK6,GATM,RAB30,MAP4K5,HPS5,IRF8,LRRC25,DOCK7,JAK2,KIT,ASPRV1,ADAM22,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,PFKFB3,CDK14,RASGEF1B,RAB39A,SLC22A23,MARCH1,PID1,C1orf54,ROGDI,ZDHHC14,SNX22,PRR5L,LRRK2,KCNIP3,RTN1,SEMA6D,MRAS,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,FNBP1,SULF2,SEPT3,CYB561A3,TRPM2,CADM1,SIGLEC10,PLD4,PIANP" Coexpression Atlas GSM605826_500 "Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1" "Immgen.org, GSE15907" 4.14E-03 1.00E+00 1.48E-02 1.35E-01 83 383 "PTCHD1,ALCAM,FGD2,APP,SHTN1,CASK,CADM3,ADAM23,ST3GAL5,CACNA1E,DDR1,HAP1,CD86,CHN2,B4GALT6,LY86,CSF1R,CTNND2,USP6NL,CYBB,DOCK4,MYADM,SIRPA,CDON,DSCAM,ARRDC4,PLXNC1,PLEKHA1,EPS8,IGSF6,TLR7,SIRPB1,FGR,GATM,HPGDS,RAB30,GPM6B,ADAP1,ZNF496,GSN,ATG4C,FRMD5,LRRC25,DOCK7,IL6R,ITGAM,JAK2,KIT,STK32C,ADAM22,MYO5A,CLEC9A,CDK14,ABCB1,PLTP,RASGEF1B,PTAFR,PID1,ROGDI,RGS12,LRRK2,KCNIP3,RTN1,SCN3A,ST8SIA1,SLC8A1,CCDC88A,SLC12A2,RGL1,SULF2,ADGRL3,CYB561A3,SLC44A1,DDHD1,TNS1,TPD52,NPL,TRPM2,TRPS1,SPIRE1,SIGLEC10,PLD4,NLRP3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal C_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal C_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.17E-03 1.00E+00 1.48E-02 1.35E-01 62 273 "NDRG2,AGT,SPARCL1,LTBP4,TMEM263,SGCE,RUNX1T1,CD81,CDO1,CHN1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,DTNA,GOLT1B,EDNRA,TMTC1,PCOLCE2,BSCL2,LRRC17,ETV1,TMEM132C,FHL1,FOXF2,DKK3,FREM1,SPIN1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,KCNK3,NRCAM,DDR2,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,LIMCH1,PALLD,MYCBP2,PDLIM2,USP22,TGFBR3,HHIP,TTC3,PMEPA1,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal C_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal C_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.17E-03 1.00E+00 1.48E-02 1.35E-01 62 273 "NDRG2,AGT,SPARCL1,LTBP4,TMEM263,SGCE,RUNX1T1,CD81,CDO1,CHN1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,DTNA,GOLT1B,EDNRA,TMTC1,PCOLCE2,BSCL2,LRRC17,ETV1,TMEM132C,FHL1,FOXF2,DKK3,FREM1,SPIN1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,KCNK3,NRCAM,DDR2,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,LIMCH1,PALLD,MYCBP2,PDLIM2,USP22,TGFBR3,HHIP,TTC3,PMEPA1,TUBA1A" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k2 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.24E-03 1.00E+00 1.51E-02 1.37E-01 10 25 "CHGB,ELAVL4,DNER,STMN2,MAP4,NEFM,MAPK10,PRPH,SNAP25,SCN3B" Coexpression Atlas gudmap_kidney_P4_CapMesRenVes_Crym_k3_100 kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.24E-03 1.00E+00 1.51E-02 1.37E-01 10 25 "VCAN,FGFR1,IGSF5,GFRA1,NCAM1,PENK,TMEM100,SALL1,CUX2,CADM1" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K4 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 4.26E-03 1.00E+00 1.51E-02 1.38E-01 53 227 "PLA2G6,ATP2B1,TTLL9,BCHE,NRP2,OSGIN2,CA4,CA12,CBLN1,INA,CLCN3,AKAP12,CHRDL1,ST8SIA3,PLEKHA1,RASGRP2,PIPOX,CD320,TUBB4A,AMOTL2,SEMA4D,NOP56,GPR153,KIAA1958,LPAR4,CECR2,HSP90AA1,SLC35G1,CDH20,AQP11,IGSF11,PRTG,PLTP,MAGEL2,FSD1,GDPD2,PTPN13,CEP97,SALL1,SNRPN,BEX1,PBLD,AJAP1,MTCL1,BEX4,RGMB,TST,CFAP298,ZIC2,ZBTB16,LAMP5,CA10,RGMA" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_500 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 4.27E-03 1.00E+00 1.51E-02 1.38E-01 18 58 "ARHGAP20,CBLN1,VCAN,EDNRA,PLXNC1,FABP7,FREM1,GHR,GUCY1A1,NCAM1,PDGFRA,RASGEF1B,LAMA1,ROBO1,ROBO2,MEG3,TMEFF2,VSNL1" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_100 DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.28E-03 1.00E+00 1.52E-02 1.38E-01 24 85 "DOC2A,CALB1,CRLF1,TMEM59L,IPCEF1,CNTNAP2,CTH,DUSP9,EMX2,SPSB4,RASL10A,GFRA1,MFSD2A,FRMD5,KCNJ16,L1CAM,VWA2,LAMA1,RASGRF2,RET,SCN8A,LRRC4,RPRM,VSNL1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_100 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.31E-03 1.00E+00 1.53E-02 1.39E-01 5 8 "CADPS,PLXNA4,IGSF5,RTN1,FAM19A1" Coexpression Atlas gudmap_developingKidney_e15.5_Medullary collecting duct_1000 DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.31E-03 1.00E+00 1.53E-02 1.39E-01 157 786 "RALGAPA1,METAP1D,ADORA1,AP2A2,OSBPL6,AMPD3,OGT,ANK3,APC,EPB41L5,DGKD,AQP4,SFMBT2,CASK,ARHGDIG,PDE8B,ATP1A1,RGS11,BMP7,SCAPER,CA4,CALB1,CANX,HIP1R,MAP7,USP2,LRRFIP1,CBARP,B4GALT6,CLCN3,CLCN4,FAM149A,COL4A5,AHCTF1,SLC35F1,ENTPD4,RBM39,CRYM,IPCEF1,PLCH2,VCAN,CNTNAP2,CTH,PHF19,AIF1L,MFAP3L,DDX46,PDCD6IP,SNX29,HIPK3,SEMA3D,EIF5,TENM1,EIF1,EMX2,ENO2,VPS13B,EPB41,SLC43A2,F3,F5,EFEMP1,ATP8A1,RACK1,KIAA1109,PRKAG2,SUCO,FOXO3,ANKFY1,APOPT1,RASL10A,CAMKK2,DKK3,GALC,RAPGEF6,IQGAP2,STARD10,IGSF5,GFRA1,PPARGC1A,GJB1,CCDC184,GRB10,DIDO1,GSTT2,PADI2,ICA1,SCIN,SLC35G1,KCNC2,KCNJ10,KCNJ16,KCNK1,KIF2A,L1CAM,LIFR,AQP11,MBP,CHIC1,SCAMP5,MKLN1,MYO6,VWA2,PIK3C2A,RETREG1,JAKMIP1,PLXNB1,ANKRD16,STRN3,MBOAT7,KANSL1,PKN2,GON4L,PTPRO,RAP1GAP,ZDHHC14,DPF2,REV3L,PRR5L,EMID1,MEG3,SCN8A,SOX6,SFPQ,PPP1R9A,HKDC1,RUFY2,NAPB,MYCBP2,SPP1,ATP10B,LRRC4,STX1A,FGD4,PRRC2C,DNMBP,CAMSAP2,WWC1,MGRN1,WSCD1,OBSL1,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,RPRM,UGT8,PDIA2,ZNF23,LYPD6,TMEM178A,SEMA3B,FIP1L1,GOPC,DOCK8,NUP214" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_100 FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100 FaceBase_RNAseq 4.32E-03 1.00E+00 1.53E-02 1.39E-01 27 99 "PCDH10,LGR5,KCNAB3,NTM,KBTBD11,EMX2,EPHA5,ADGRV1,ATP8A1,NSG1,DKK3,LRRC4B,NFIA,PAX6,PDE4D,PENK,SEMA5B,PLTP,POU3F4,RGS10,RTN1,MAPK8IP3,WSCD1,TNNT1,UCHL1,SLAIN1,PLPPR2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K1 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.33E-03 1.00E+00 1.53E-02 1.39E-01 51 217 "ACTN2,ADCY2,KIAA1324,ARHGAP20,ZFYVE28,PDE8B,ADGRB2,C1QC,LDLRAD4,REPS2,KCNAB3,VAX2,CSF1R,DLG2,DRP2,SNX29,RASA4,EPS8,DLL3,FYB1,ARPP21,TMEM8B,LYVE1,GLRB,GNG4,GUCY1B1,GPR155,NEXMIF,NELL1,NPR2,PLCL1,TRHDE,NXPH1,PRKAR1B,ZCWPW1,ZNF493,ZMAT4,PRIMA1,STK32B,MRAS,SH3GL2,ASAP3,SLC1A2,SLC6A9,ZFR2,FAM189A1,KCNE5,CADM2,LRP8,PCDH15,DPF3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.33E-03 1.00E+00 1.53E-02 1.39E-01 51 217 "CCDC85A,ADGRF5,SPARCL1,SEMA6A,PRX,ADAM15,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,CALCRL,ST3GAL6,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,AFDN,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_500 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.33E-03 1.00E+00 1.53E-02 1.39E-01 14 41 "ADCY5,NRP2,CACNA2D1,RAB3C,ABCC9,CALCRL,CAP2,IL6ST,KCND3,KCNMA1,NPTX2,RYR3,HHIP,SYNPO2" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k1 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.34E-03 1.00E+00 1.53E-02 1.40E-01 31 118 "EPB41L5,ATM,CA8,CLTA,PPP1R16B,ARHGAP24,FAM107B,KBTBD11,ABCC9,EDNRB,ST3GAL6,CGREF1,ILDR2,IGSF5,GUCY1A1,GUCY1B1,ITGAV,TM6SF1,MEF2C,NRDC,PFKP,RETREG1,SCHIP1,IRX1,PTPRG,PTPRO,ZDHHC14,SGK1,DDN,NPL,TMEM178A" Coexpression Atlas gudmap_developingKidney_e15.5_Proximal Tubules_1000_k3 DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.35E-03 1.00E+00 1.53E-02 1.40E-01 38 152 "RALGAPA1,OGT,EPB41L5,DGKD,SLC4A4,CACNA2D1,CANX,CLCN3,OSBPL3,ARHGAP24,GOLT1B,EIF4G2,SYNCRIP,SGIP1,RAPGEF6,GHR,PPARGC1A,GRB10,PIK3C2A,RETREG1,KANSL1,BCAS3,REV3L,LGR4,FAM126B,ZHX3,MYCBP2,NPAS3,PRRC2C,VPS13A,CAMSAP2,WASHC4,ZFP91,ERCC6L2,RGMB,TRIO,TRPS1,KLHDC1" Coexpression Atlas GSM538343_500 "B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1" "Immgen.org, GSE15907" 4.37E-03 1.00E+00 1.54E-02 1.40E-01 87 405 "CPNE2,FMNL2,SNX30,ZNF608,MTUS1,OSBPL1A,ABCD2,ATP1A3,BLM,ST3GAL5,PRC1,ADGRG1,FADS2,LY86,CNN3,GDA,CSF1R,CSF3R,NOS1AP,CYBB,ARHGAP32,KIAA0513,SIRPA,DNAJC6,EBF1,SNX29,SEMA3D,RASA4,CALCRL,PAN3,GPHN,IGSF6,TLR7,SIRPB1,EYA1,F5,CHST15,SMC2,ARPP21,GATM,GCNT2,GFRA1,ARHGAP19,SCRG1,HP,ICA1,IRF8,DOCK7,IL12A,ITGAM,KIT,STMN1,LIFR,ASPRV1,MEF2C,MEIS1,MN1,MYCN,MYO5A,P2RY13,PBX1,ANLN,PILRA,PYGM,RNASEL,UEVLD,ATP8B4,LRRK2,SATB1,SELL,ITSN1,BTBD3,TET1,SSTR2,RGL1,FGD4,ANKRD28,TCF4,DMXL2,SYNE1,CYB561A3,TF,CBX5,BHLHB9,TNS1,STXBP4,SSBP2" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal D_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal D_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.38E-03 1.00E+00 1.54E-02 1.40E-01 69 310 "NDRG2,C1QTNF1,SPARCL1,SRPX,LTBP4,ATP1A2,MPDZ,RUNX1T1,ENTPD2,CD81,CDO1,SLIT2,MAGED1,CNRIP1,CP,AKAP12,VCAN,DOCK4,MYADM,ZEB2,ECM2,EDNRA,PCOLCE2,LRRC17,ETV1,FGFR1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,IL11RA,LAMA2,MN1,CCDC80,FXYD6,NFIA,NFIX,DDR2,PBX1,PDGFRA,PENK,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,PID1,ROBO2,ZNF354C,TNFRSF19,SEC31A,LIMCH1,PALLD,ZCCHC24,MYCBP2,PDLIM2,TGFBR3,HHIP,RFTN2,UBE2H,PMEPA1,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal D_PND07-28_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_mesenchymal D_PND07-28_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.38E-03 1.00E+00 1.54E-02 1.40E-01 69 310 "NDRG2,C1QTNF1,SPARCL1,SRPX,LTBP4,ATP1A2,MPDZ,RUNX1T1,ENTPD2,CD81,CDO1,SLIT2,MAGED1,CNRIP1,CP,AKAP12,VCAN,DOCK4,MYADM,ZEB2,ECM2,EDNRA,PCOLCE2,LRRC17,ETV1,FGFR1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,IL11RA,LAMA2,MN1,CCDC80,FXYD6,NFIA,NFIX,DDR2,PBX1,PDGFRA,PENK,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,PID1,ROBO2,ZNF354C,TNFRSF19,SEC31A,LIMCH1,PALLD,ZCCHC24,MYCBP2,PDLIM2,TGFBR3,HHIP,RFTN2,UBE2H,PMEPA1,TUBA1A" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_100 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.39E-03 1.00E+00 1.54E-02 1.41E-01 22 76 "PCDH19,DOC2A,CA4,SLC32A1,CRYM,GREB1,DUSP9,PSD2,GALC,GLDC,PRDM5,HES5,CLEC18A,MID1,NPY,OXTR,PRTG,TMEM100,PRR5L,EMID1,SALL1,HEY1" Coexpression Atlas gudmap_kidney_P0_JuxtaGlom_Ren1_k3_500 kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.39E-03 1.00E+00 1.54E-02 1.41E-01 22 76 "CACNA2D1,ARHGEF6,DGKB,ABCC9,EBF1,FRY,RCAN2,RASGRP2,GUCY1A2,GUCY1A1,GUCY1B1,MARK1,CCDC80,PDE3A,SERPINE2,SERPINI1,FXYD1,ZDHHC14,SLC8A1,SLC12A2,TNS1,TRPC1" Coexpression Atlas facebase_RNAseq_e10.5_NeuroEpith_central_2500_K3 facebase_RNAseq_e10.5_NeuroEpith_central_2500_K3 Gudmap RNAseq 4.40E-03 1.00E+00 1.55E-02 1.41E-01 20 67 "CPNE2,ADD2,NRXN3,ABCG1,AATK,KIF26A,SEZ6L2,EMX2,EPHB1,CCDC184,GUCY1A2,MAPT,SHC3,KITLG,NTRK2,SERPINI1,LIMS2,TACC1,TRPC1,TMEFF2" Coexpression Atlas Facebase_RNAseq_e10.5_Mandibular Arch_1000_K2 FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 4.43E-03 1.00E+00 1.56E-02 1.42E-01 47 197 "ACTN2,ADCY2,ARHGAP20,APOC2,ADGRB2,ZNF599,C1QC,LDLRAD4,REPS2,KCNAB3,CRYBB1,CSF1R,PLCH2,DLG2,RASA4,EPS8,FYB1,ARPP21,TMEM8B,GLRB,ADAP1,KNDC1,IL11RA,MOBP,NEXMIF,PLCL1,NXPH1,PRKAR1B,STRC,ACSS3,ZCWPW1,ZMAT4,DUSP15,MYH14,ASAP3,SLC1A2,SLC6A9,C11orf87,ZFR2,UNC5D,ADGRL3,FAM189A1,TMOD1,CADM2,PCDH15,DNAH10,DPF3" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K1 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 4.44E-03 1.00E+00 1.56E-02 1.42E-01 41 167 "DISP3,CEP126,PDE8B,ATP1A3,LDLRAD4,CACNA2D1,CAMK2A,NIPBL,COL9A2,DRP2,ABCC9,TMTC1,DLL3,STAU2,ZMAT1,TMEM8B,NTNG2,GNG4,LRRCC1,IGSF1,CREG2,GPR155,CPNE9,MSR1,NPR2,PDE4D,GPSM2,PRRX1,SDK2,DIRAS2,CNTLN,IQSEC3,ZNF493,BEND5,MRAP2,SLC1A2,ACSBG1,SATB2,PIK3R5,SYNPO2,TRPS1" Coexpression Atlas gudmap_kidney_P0_CapMes_Crym_k3_200 kidney_P0_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.46E-03 1.00E+00 1.56E-02 1.42E-01 13 37 "CNTFR,CRYM,PHF19,SNAP91,ELAVL4,ETV1,EYA1,HAS2,NEGR1,MEIS2,NELL1,FAT3,SLC1A3" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_100 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.46E-03 1.00E+00 1.56E-02 1.42E-01 13 37 "AMH,CADPS,CACNA2D2,CLU,DTNA,MRO,EPS8,ERBB4,PTK2B,FGF13,PAK3,SERPINE2,RASGEF1B" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K4 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#4 FaceBase_RNAseq 4.51E-03 1.00E+00 1.57E-02 1.43E-01 28 104 "ARHGAP20,ZFYVE28,ATP1A3,ADGRB2,C1QC,IL33,KCNAB3,CSF1R,RABGAP1L,SEMA3D,SEZ6,DLL3,ABLIM2,FYB1,ARPP21,TMEM25,IGSF1,MID1,STRC,ZMAT4,DUSP15,SOX8,C11orf87,ACSBG1,ZFR2,FAM189A1,TMOD1,DNAH10" Coexpression Atlas gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k1_100 dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 4.51E-03 1.00E+00 1.57E-02 1.43E-01 12 33 "AMH,CADPS,CLU,DTNA,EPS8,ERBB4,PTK2B,FGF13,GPM6B,PAK3,SERPINE2,RASGEF1B" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 4.51E-03 1.00E+00 1.57E-02 1.43E-01 12 33 "CSF1R,CX3CR1,CYBB,LPAR6,FYB1,VSIG4,MEF2C,TREM2,RGS10,SPP1,P2RY12,SLC38A1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_40_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_40_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.51E-03 1.00E+00 1.57E-02 1.43E-01 12 33 "CSF1R,CX3CR1,CYBB,LPAR6,FYB1,VSIG4,MEF2C,TREM2,RGS10,SPP1,P2RY12,SLC38A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k3 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 4.51E-03 1.00E+00 1.57E-02 1.43E-01 12 33 "SORCS1,CADPS,CDH10,DCLK1,SYNPR,RSPO2,CLDN11,GPR85,TRHDE,RGS4,SCN3A,FAM19A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k4 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 4.55E-03 1.00E+00 1.59E-02 1.45E-01 25 90 "SORCS2,SEMA6A,DPP10,SEMA4G,CACNA1B,KALRN,CTNND2,BRINP1,CALN1,DACH2,MEGF11,SYT17,GFRA1,KIAA1958,ASPRV1,MSI1,ARMH4,HES6,ZFP2,SLC8A3,SLC15A2,IFT122,SOX2,SZT2,TIAM1" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500 DevelopingKidney_e12.5_renal vesicle_emap-27679_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.57E-03 1.00E+00 1.59E-02 1.45E-01 88 411 "RNF157,ADORA1,PCDH19,DOC2A,AMPH,BMP7,CA4,CA12,CALB1,CAMK2B,TBRG4,CRLF1,FAM189A2,PICK1,SLC32A1,CRYM,TENM4,KIAA0040,GREB1,SNAP91,USP3,DUSP9,HEYL,PCOLCE2,EMX2,EPHB1,EYA1,RACK1,ST3GAL6,FKTN,SLC9B2,SPSB4,FGFR1,PSD2,SGIP1,HVCN1,TRIM16,RASL10A,CGREF1,TVP23A,GALC,IGSF5,BRD8,GLDC,ADGRA3,B4GALNT4,DIDO1,PRDM5,MFSD2A,HAS2,HES5,KCNC2,KCNJ16,KIF5C,CLEC18A,MARK1,TM6SF1,MID1,PTOV1,VWA2,NPY,NPTX1,OXTR,PRTG,PDE1C,PLXNB1,ANKRD16,LAMA1,NKAIN1,GAL3ST4,DUSP15,TMEM100,PRR5L,EMID1,FOXRED2,SALL1,MAPK12,SCN8A,SH3BGR,DHX30,SYT11,HEY1,CA14,NSD2,LRP8,TMEM178A,URM1,PCBP4" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Matrix Endothelial_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Matrix Endothelial_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.58E-03 1.00E+00 1.59E-02 1.45E-01 55 238 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNOT8,ABCG2,CNN3,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,LPAR6,CALCRL,FAM198B,FLT1,PCDH17,LYVE1,STMN2,GRB10,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,RIPOR1,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,NSFL1C,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Matrix Endothelial_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_Matrix Endothelial_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.58E-03 1.00E+00 1.59E-02 1.45E-01 55 238 "ADGRF5,SPARCL1,SEMA6A,LDB2,SCARB1,CD38,CNOT8,ABCG2,CNN3,ABCG1,PPP1R16B,MYEF2,EDIL3,EDNRB,KLHL5,LPAR6,CALCRL,FAM198B,FLT1,PCDH17,LYVE1,STMN2,GRB10,ICA1,KIT,STMN1,LMO2,MEF2C,MEST,KITLG,CD200,PDE4B,PLTP,SNRK,PTPRB,RIPOR1,C1orf54,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,NSFL1C,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_200 dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.60E-03 1.00E+00 1.60E-02 1.46E-01 17 54 "LGR5,CALB1,DOCK4,DAPK1,DRP2,EMX2,NRN1,GABRA4,KLHL23,MATN2,KITLG,LGR4,SLC4A3,UHRF1BP1L,ADGRL3,ACTR6,FNDC5" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k2 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.60E-03 1.00E+00 1.60E-02 1.46E-01 17 54 "PCDH10,RUNX1T1,DCLK1,CRLF1,SCRN1,DLX1,TMEM132C,FOXF2,SGIP1,MEGF10,GABRA4,GRIA2,PRRX1,ZFHX4,LIMCH1,SOX11,UNC5D" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-2fold-vs-M DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-2fold-vs-M_top255_255 Gudmap Mouse MOE430.2 4.63E-03 1.00E+00 1.61E-02 1.46E-01 54 233 "AXIN2,PCDH10,USP28,SEMA4G,BCL7A,MTMR2,TRIM41,LARGE1,CRLF1,RAB3C,ABCG2,PCYT1B,NCOR2,GREB1,SCRN1,PITPNC1,TIAM2,ARNT2,USP3,DUSP9,TBC1D16,TMEM132C,TUBB3,CEP78,DCTN2,ZBED3,MEGF11,SPIN1,GLI2,NRCAM,NUMA1,SSH1,SLC22A23,RGS12,KIRREL1,RIMKLA,HES6,PPM1E,FHOD3,DZIP1,POGZ,NEK4,SULF2,SYNE2,SIN3B,SATB2,TCF7,CA14,TSC2,WNT7A,FMN2,ZNF184,ZNF213,CERS6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Intermediate Fibroblast_E16.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Intermediate Fibroblast_E16.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 4.72E-03 1.00E+00 1.64E-02 1.49E-01 52 223 "ACTN1,NDRG2,SPARCL1,LTBP4,FUBP1,RUNX1T1,CBR1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,BOC,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,SFR1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,SEC61A2,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,USP22,TGFBR3,HHIP,ST7" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Intermediate Fibroblast_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_Intermediate Fibroblast_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 4.72E-03 1.00E+00 1.64E-02 1.49E-01 52 223 "ACTN1,NDRG2,SPARCL1,LTBP4,FUBP1,RUNX1T1,CBR1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,BOC,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,SFR1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,SEC61A2,ROBO1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,USP22,TGFBR3,HHIP,ST7" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200 dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.73E-03 1.00E+00 1.64E-02 1.49E-01 35 138 "ARHGAP20,AMH,CADPS,CBLN1,CLU,MICAL2,VCAN,EDNRA,MRO,PLXNC1,PTK2B,DLC1,AFF2,GATM,FREM1,GUCY1A1,KLHL23,MATN2,PAK3,PDE1A,PDGFRA,SERPINE2,PCDH18,FAT3,RASGEF1B,PTCH1,TMEM255A,ROBO2,SMOC1,ADGRL3,ZFPM2,HHIP,STOX2,ADAMTS9,WNK3" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgFPL_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg_Subtype_hProgFPL_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 4.74E-03 1.00E+00 1.64E-02 1.50E-01 69 311 "TTYH1,LRRC4C,ASCL1,BARD1,BMP7,FUBP1,PRC1,SEPT7,CDH2,CDO1,JAM2,IGDCC3,NECTIN3,TENM4,TOX,DCC,ZEB2,RCAN1,EEF1D,AASS,EN2,EFS,ADGRV1,FAM198B,FABP7,FDFT1,FGFR3,CAMSAP1,SMC2,PDLIM5,RND1,DBF4,CBX1,HMGB1,HES5,MEST,MSI1,NASP,NELL2,NRCAM,GPSM2,FAT3,POU3F2,PPP2R5E,SPDL1,PTPRO,PTX3,ARID4A,ZMAT4,RFX4,NUDT11,SALL1,HES6,SFPQ,PUF60,ANKRD6,SEPHS1,TET1,LIMCH1,SOX2,LMO3,POGZ,SYNE2,TCF12,PSD3,TMPO,USP1,NSD2,FZD3" Coexpression Atlas gudmap_developingGonad_P2_testes_200_k4 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 4.80E-03 1.00E+00 1.66E-02 1.51E-01 19 63 "TMCC3,NR0B1,C1QTNF3,AMH,SEMA7A,MMD2,ADGRG1,PLPPR4,EBF1,PLXNC1,LRRC17,GATM,HSD17B1,IL6ST,MYO7A,NFIX,PAK3,SEMA5B,EFHD1" Coexpression Atlas GSM538216_500 "B cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3" "Immgen.org, GSE15907" 4.81E-03 1.00E+00 1.66E-02 1.52E-01 76 348 "SNX30,ZNF608,TXNDC16,BCAR3,FGD2,DGKD,ATP6V0A1,BCL7A,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,LY86,CNN3,AKAP12,CSNK1G3,RUBCN,CYBB,HDAC9,RIPOR2,ARHGAP24,GUCD1,SLC12A6,EBF1,SNX29,FRY,SRPK3,RASGRP2,DENND4A,TLR7,CHST15,HVCN1,ACSS1,MALT1,RAB30,EML4,CECR2,RAPGEF4,IRAK3,BACH2,IRF8,IL12A,LIFR,LMO2,PIK3AP1,GPR155,MEF2C,CD200,MYO5A,NUCB2,PPP3CA,PPP3CC,RASGEF1B,PRKCB,PXK,MARCH1,BEND5,ZDHHC14,RFX5,LRRK2,SELL,ST6GAL1,LMBRD1,ARHGAP26,SLC37A2,PSD3,CYB561A3,C9orf85,VAV2,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k2_500 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.83E-03 1.00E+00 1.67E-02 1.52E-01 30 114 "LDLRAD4,CD86,CD38,LY86,CSF1R,CX3CR1,CCDC3,ABCC9,EDNRB,IGSF6,F8,FCGR1A,FYB1,LYVE1,NCKAP1L,IRF8,TM6SF1,MSR1,PTPRB,PRR5L,SGK1,ST8SIA1,SLA,KLHL4,ARHGAP9,TEK,TLR4,NPL,RGS7BP,FAM13C" Coexpression Atlas gudmap_developingGonad_e18.5_testes_500 DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.90E-03 1.00E+00 1.69E-02 1.54E-01 88 412 "ACLY,TKTL1,ARID1A,DSCAML1,TMCC3,ADD1,AGT,NR0B1,SORCS2,C1QTNF3,LTBP4,AMH,SEMA7A,DGKD,ARHGDIG,BACH1,ST3GAL5,MMD2,BTRC,DDR1,CALM1,CBLN1,SCARB1,ADGRG1,JAM2,CLU,FADS2,NIPBL,RBM39,RNF14,PUM1,ARHGAP32,DAPK3,SPOCK2,DBI,DCTN1,PLPPR4,RCAN1,DTNA,DNM1L,EBF1,EDNRA,MBNL2,PLXNC1,ELN,EPB41L2,LRRC17,FGFR1,GATM,GPM6B,GPR37,GRB10,MAEL,HSD17B1,IL6ST,TUBB2B,JAK1,MEF2C,MT3,MYO7A,NEXMIF,NFIX,NNAT,PAK3,PDGFRA,SEMA5B,PCDH18,RC3H2,PTPRE,MEG3,ARX,EFHD1,SON,ZCCHC24,SPP1,SULF2,ACSBG1,OBSL1,PUM2,TEX15,HHIP,TNS1,TST,UCHL1,USP1,ZFAND5,PCBP4,RTN4" Coexpression Atlas ratio_EB_vs_SC_500_K4 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#4 PCBC 4.92E-03 1.00E+00 1.70E-02 1.55E-01 16 50 "SERPINA3,AGT,AKAP6,TPPP3,ATOH8,UBE2QL1,SYNPO,IGF1,KIAA1755,MYH6,MYL3,NCAM1,RXRG,FNDC5,ZBTB16,DPF3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_200 dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 4.96E-03 1.00E+00 1.71E-02 1.56E-01 44 183 "NR0B1,PPP4R4,TMEM108,MYRF,CALB1,CBLN1,CDH10,DCLK1,HAPLN1,ATRNL1,PLXNA4,DOCK4,DCT,DRP2,EDNRA,PLXNC1,EMX2,F3,FLNC,GABRA4,FREM1,PCDH11X,GUCY1A1,KCND2,KLHL23,MEIS1,NEFM,PDE1A,PDGFRA,SERPINI1,PCDH18,PRRX1,RASGEF1B,PTN,ROBO2,TMEM206,PALLD,UHRF1BP1L,SMOC1,ADGRL3,ZFPM2,ACTR6,TNNT1,DPF3" Coexpression Atlas gudmap_developingGonad_P2_testes_500_k1 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 4.97E-03 1.00E+00 1.71E-02 1.56E-01 31 119 "AMH,SEMA7A,ARHGDIG,ST3GAL5,DDR1,CBLN1,ADGRG1,CLU,FADS2,RCAN1,DTNA,EDNRA,MBNL2,EPB41L2,FYN,GPM6B,GPR37,JAK1,TTYH2,MEF2C,MT3,PAK3,PDGFRA,SEMA5B,TMEM206,MEG3,ARX,ACSBG1,HHIP,TST,SGK3" Coexpression Atlas PCBC_EB_fibroblast_100 Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100 PCBC 5.01E-03 1.00E+00 1.73E-02 1.57E-01 27 100 "LHX2,IGLON5,COL9A1,ELAVL3,ELAVL4,ZIC4,NSG2,GPM6A,STMN2,CELF3,SCRG1,KCNQ2,RSPO2,NELL1,NTRK2,GDAP1L1,POU3F2,NKAIN4,PRPH,SST,SYT4,TAC1,CNTN2,TF,ZIC1,CRB2,STMN4" Coexpression Atlas PCBC_MESO-5_fibroblast_500 Progenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500 PCBC 5.02E-03 1.00E+00 1.73E-02 1.57E-01 103 493 "KCNH8,SORCS1,ADORA1,NR0B1,UNC79,PDZD4,APOC1,LGR5,ARSE,KIF1A,FGF17,BMP7,BTK,C5,MYRF,CCK,CCKBR,USP2,CDH8,IGLON5,COL9A1,COL9A2,COL9A3,GAL3ST1,NRG2,CNTNAP2,PPP1R16B,PLCXD3,SV2B,FAM78B,USH1C,EFNA2,ELAVL4,ERBB4,RASL12,ADGRV1,C1orf61,B3GAT1,TBR1,MEGF10,HRASLS5,GABRB3,SALL3,ATP8A2,GATM,FREM1,GNAL,GPM6A,TMEM121B,GRIK3,PTPN5,FAM222A,HAS2,IGFBPL1,HP,KCNF1,CLVS2,KCNJ3,KCNQ2,KIT,MATN3,SCG3,MYT1,NODAL,IGSF11,SEMA5B,A2ML1,JAKMIP1,MAGEL2,PACSIN1,RELN,LAMA1,ELOVL2,STK32A,SLC25A48,FAM184A,KHDRBS2,PRIMA1,RXRG,SALL1,TMEM200C,SOX10,MCF2L2,SSTR2,ZFR2,TMEM150C,FAM189A1,LEFTY2,GALNT17,TMOD1,PIK3R5,SEZ6L,TRPM2,CA14,RPRM,ETNPPL,KCNK12,ZIC3,FMN2,ANKS1B,CADM2,GAL3ST3,JPH3" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 5.10E-03 1.00E+00 1.76E-02 1.60E-01 65 291 "ABCF1,BBS2,PTBP2,CDK11B,LRBA,DIS3L,COG1,NIPBL,IGDCC3,PREPL,PHF14,ARHGAP32,KIAA0586,IST1,SNX29,WDPCP,KLHL5,EPB41,NSRP1,WAC,FDFT1,AFF2,SMC2,UFM1,ADGRA1,C15orf41,MMADHC,RFFL,CIT,KCNJ5,KIF5C,LSS,POC1B,RSPO2,NASP,NFE2L2,NFIX,SMIM11A,NTRK3,OCRL,OPA1,CCSER2,DRAM2,DIRAS2,ARID4A,ZYG11B,CLIP1,CCDC88A,MBD5,SPATA7,BDP1,SOX11,SRPK2,HHIP,STXBP4,TRPS1,ZKSCAN5,USP1,ZFP37,ZNF184,UPF3A,EMSY,EVI5,HNRNPA3,ZNF248" Coexpression Atlas Facebase_ST1_e9.5_MandibArch_500_1 e9.5_MandibArch_top-relative-expression-ranked_500_1 FaceBase_ST1 5.12E-03 1.00E+00 1.76E-02 1.60E-01 73 333 "PDXK,FGF17,BID,BMP7,CA4,CBLN1,INA,CIART,LHX2,NMT2,FAM19A5,SULT4A1,CNTFR,CTH,JAKMIP2,FBXL5,GSDME,RAB39B,ST8SIA3,EDN1,LPAR6,PLEKHA1,EML1,PIPOX,REEP2,ARMCX1,CEP78,NOP56,PRELID3A,C15orf41,GATM,C1QL1,GLDC,TOX3,PCSK1N,PRDM5,KAT7,FRMD5,ELOVL5,ICA1,IPO5,LMO1,MAOB,AQP11,CHIC1,MYCN,PAX6,PPP2R5C,PRKCZ,ELOVL2,PTPRZ1,DPF2,RPRD1A,TMEM206,ARMH4,ADAL,RMI1,MAPK12,SLC4A3,SOX2,SPATA7,LHPP,TAC1,MTCL1,ROBO3,WSCD1,DMXL2,TIMP4,TPD52,TRH,SLAIN1,PDSS2,ZDHHC20" Coexpression Atlas gudmap_developingGonad_e16.5_testes_500_k2 DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.18E-03 1.00E+00 1.78E-02 1.62E-01 33 129 "C1QTNF3,LTBP4,AMH,SEMA7A,ARHGDIG,ST3GAL5,MMD2,CBLN1,ADGRG1,CLU,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,LRRC17,GPM6B,GPR37,HSD17B1,MEF2C,MYO7A,PAK3,PDGFRA,SEMA5B,MEG3,ARX,EFHD1,SPP1,ACSBG1,OBSL1,HHIP,TNS1,TST" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500_k1 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.21E-03 1.00E+00 1.79E-02 1.63E-01 22 77 "SRPX,ARHGAP20,ATP1A2,VSTM2A,DCLK1,CP,ABCC9,EDNRA,FGF1,GABRB1,GAD1,GLUL,CNDP1,PARD3B,KCND3,MATN2,PENK,NALCN,LGI2,PCDHB9,VLDLR,RGS7BP" Coexpression Atlas GSM399376_500 "alpha beta T cells, T.4SP69+.Th, 4+ 8- TCRhi 69+, Thymus, avg-3" "Immgen.org, GSE15907" 5.22E-03 1.00E+00 1.79E-02 1.63E-01 79 365 "ACTN1,NDRG2,ADCY6,AP1B1,ARHGAP20,PITPNM2,DGKZ,DGKD,SFMBT2,GPR146,FMNL3,ARHGEF1,CNN3,LRIG1,SIPA1L1,PPP1R16B,TOX,KBTBD11,DLG4,CDON,RASGRP1,TMEM35A,TLR7,KIAA1109,TMEM164,MEX3B,CAP2,TACC2,NSG2,FYN,CHL1,KCNMB4,RAPGEF4,GSN,ADAMTS6,BACH2,ZDHHC15,IL6ST,ITPKB,KCNH2,STMN1,HECTD2,CD200,SESN3,ZNF827,PDE4D,TMIE,SLC25A23,SPATA6,PACSIN1,PPM1B,SYTL2,CEP97,BEND5,RGS3,RGS10,RAVER2,SATB1,SBF1,IL17RB,ZNF821,GALNT10,FAM102A,ST6GAL1,ST8SIA1,DZIP1,TET1,TNIK,CAND2,PJA1,TCF7,TGFBR3,SLC44A1,BHLHB9,RUNDC3B,SSBP2,TTC3,PMEPA1,SPATA13" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k3_500 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.24E-03 1.00E+00 1.80E-02 1.64E-01 15 46 "PNMA8B,APOC1,LGR5,CLU,SRGAP3,PLXNC1,FAM198B,AFF2,GATM,SHISA6,MOV10,TMEM206,SMOC1,ST5,WNK3" Coexpression Atlas ratio_EB_vs_SC_1000_K3 ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 5.29E-03 1.00E+00 1.81E-02 1.65E-01 20 68 "SERPINA3,AGT,SPARCL1,CAMK2A,AKAP6,FLNC,UBE2QL1,IGF1,MAPT,MYL3,NCAM1,PDE1C,PLCL1,PTH1R,TNS1,SYNPO2,FNDC5,TOM1L2,ZBTB16,DPF3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.34E-03 1.00E+00 1.83E-02 1.67E-01 49 209 "USP31,TAOK1,ANK3,APC,NRP2,CACNA2D1,KALRN,CANX,CRHBP,HAPLN1,VCAN,ZEB2,ARNT2,PDCD6IP,DYRK1A,HIPK3,EIF4G1,DLC1,CAMKK2,DKK3,GABRA3,IQGAP2,GFRA1,PCDH17,KLF12,BACH2,KIF2A,NFIA,PIK3C2A,PRRX1,MBOAT7,KANSL1,MAPK8,REV3L,C11orf87,EPB41L3,MAPK8IP3,STX1A,DNMBP,CAMSAP2,ADGRL3,TBL1X,HHIP,ERCC6L2,RBFOX2,RGMB,STOX2,NUP214,MSRB3" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_500_k2 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.34E-03 1.00E+00 1.83E-02 1.67E-01 35 139 "ADGRF5,ARRB1,CA8,CD86,CD38,MS4A7,LY86,CSF1R,CX3CR1,CYBB,CCDC3,DNM2,EPHB1,IGSF6,SIRPB1,F8,FCGR1A,FYB1,GGTA1P,LYVE1,NCKAP1L,TM6SF1,MSR1,NCF2,PTPRB,SGK1,ST8SIA1,SLA,ARHGAP9,TEK,TLR4,NPL,TRPC3,FAM13C,SOCS4" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_1000_k2 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.34E-03 1.00E+00 1.83E-02 1.67E-01 35 139 "EMILIN3,TAOK1,C1QTNF3,SPARCL1,ARHGAP20,LTBP4,PTCH2,DDX3Y,PUM1,ZEB2,EDNRA,MBNL2,ELN,LRRC17,CSDC2,IGF1,JAK1,LAMA2,MEF2C,NRBP2,NFIA,NFIX,PDGFRA,FXYD1,MEG3,ARX,RCOR3,TBL1X,OBSL1,HHIP,TNS1,NR2C2,UBTF,ZBTB16,PMEPA1" Coexpression Atlas gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_500 kidney single cell_e11.5_MetanephMesench_StemCellamp_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 5.41E-03 1.00E+00 1.85E-02 1.68E-01 74 339 "MTUS1,CNIH2,CDC14B,TMEFF1,ARHGDIG,ARHGEF25,HOMER3,CNTFR,IQCK,COL9A1,COL9A3,ZNF521,CSNK1E,VCAN,SDC3,ARMCX4,MYEF2,DUSP9,EBF1,PLEKHO1,TUBB4A,FGF13,FOXO3,SMC2,BRSK1,NEK6,GAP43,KCNMB4,GNG3,B4GALNT4,SERP2,PSIP1,HMGB1,ZDHHC15,KIAA1755,STMN1,LMO1,MDFI,MEIS1,MEIS2,MEST,SAMD14,MYCN,LINC00672,FXYD6,RCOR2,NNAT,NTRK2,NLE1,FSD1,PTN,C1orf54,TSPY26P,FIGN,MEG3,SH3GL3,DZIP1,CXXC4,PALLD,SOX11,FCHO1,SIN3B,CUX2,TCF7L2,C18orf54,ENHO,FNDC5,RFTN2,FAM155A,MICAL1,MEIS3,SLC38A1,PCBP4,NETO2" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 5.51E-03 1.00E+00 1.88E-02 1.71E-01 44 184 "AP1B1,BIN1,SFMBT2,ARRB2,C1QC,LY86,CSF1,CSF1R,CX3CR1,CYBB,DOCK4,ZEB2,EGR3,LPAR6,IGSF6,FCGR1A,FCGRT,FOLR2,FYB1,GATM,ADAM28,HPGDS,LILRB4,GPR34,GSN,NCKAP1L,VSIG4,IFI16,IL6R,IL6ST,MEF2C,P2RY13,OLR1,TREM2,PTAFR,GAL3ST4,RGS10,SGK1,SPP1,SAMSN1,WASHC4,P2RY12,SLC38A1,DOCK8" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl_Overall_Top_200_Genes GSE76381_EmbryoMoleculeCountsPMLog2 5.51E-03 1.00E+00 1.88E-02 1.71E-01 44 184 "AP1B1,BIN1,SFMBT2,ARRB2,C1QC,LY86,CSF1,CSF1R,CX3CR1,CYBB,DOCK4,ZEB2,EGR3,LPAR6,IGSF6,FCGR1A,FCGRT,FOLR2,FYB1,GATM,ADAM28,HPGDS,LILRB4,GPR34,GSN,NCKAP1L,VSIG4,IFI16,IL6R,IL6ST,MEF2C,P2RY13,OLR1,TREM2,PTAFR,GAL3ST4,RGS10,SGK1,SPP1,SAMSN1,WASHC4,P2RY12,SLC38A1,DOCK8" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_500 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 5.53E-03 1.00E+00 1.88E-02 1.72E-01 14 42 "CSMD3,CACNA1B,CACNA1E,ABCC9,EBF1,DENND4A,RAB30,LSAMP,NTRK3,PDE3A,SCN2A,FAM19A1,ASTN2,TNR" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_200_k4 DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.53E-03 1.00E+00 1.88E-02 1.72E-01 14 42 "DOC2A,BMP7,GREB1,NTM,DUSP9,ST3GAL6,IGSF5,HES5,CLEC18A,OXTR,LAMA1,EMID1,SALL1,WSCD1" Coexpression Atlas gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000 dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.53E-03 1.00E+00 1.88E-02 1.72E-01 30 115 "HFM1,CPNE5,CAPRIN2,ATM,NAE1,SCAPER,LONRF2,DZIP3,EDRF1,FBXL5,DUSP9,SCML2,KIAA1109,EFCAB2,MAP7D2,MAEL,ADAM22,PPP2R5C,ZCWPW1,HSPA4L,SH3BGR,CNKSR2,ZNF667,GKAP1,VPS13A,DMXL2,TEX15,RUNDC3B,TRPC1,UGT8" Coexpression Atlas Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K2 FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 5.54E-03 1.00E+00 1.88E-02 1.72E-01 65 292 "EMILIN3,SRPX,CDK10,CACNA1G,CACNA2D1,RUNX1T1,CDO1,CRLF1,CLTB,COL9A2,ABI3BP,ANKRD44,CCDC3,ABCC9,ELN,EPB41L1,LRRC17,FCGRT,TRIM16,STAU2,TVP23A,ZMAT1,ZNF276,GRIK4,WIF1,SYNPO,IL11RA,CREG2,VWA5A,SRSF12,CD200,MSR1,RSPO2,TCEAL5,FXYD7,NFIX,NRGN,CNTN3,PDE1A,PDE4D,PRRX1,SDK2,EPB41L4B,CNTLN,ACSS3,IQSEC3,RAP1GAP,BEND5,ZFHX4,MRAP2,LRRK2,DGLUCY,ATXN1,SH3GL3,DOCK10,SLC8A1,PLCB1,ADGRL3,SATB2,PHF24,PIK3R5,TRPS1,TSPAN11,PMEPA1,KLHDC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urethra_100_k4 DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.54E-03 1.00E+00 1.88E-02 1.72E-01 9 22 "DPP10,CDH10,JAKMIP2,GFRA1,RSPO2,NDP,CLDN11,SCN3A,HHIP" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_PND01-03_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_PND01-03_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 5.56E-03 1.00E+00 1.89E-02 1.72E-01 54 235 "NDRG2,SPARCL1,LTBP4,TMEM263,SGCE,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,BSCL2,EPB41L2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,PBX1,PDGFRA,SERPINE2,ZFYVE21,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,PDLIM2,TCF12,TGFBR3,HHIP,THRA,CBX5,TUBA1A,ST8SIA2" Coexpression Atlas GSM538303_500 "NK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3" "Immgen.org, GSE15907" 5.61E-03 1.00E+00 1.90E-02 1.74E-01 88 414 "AS3MT,ADORA2A,KCNAB2,GAS7,CDC14B,INSYN2B,BAIAP3,CAMK2B,ARHGEF1,CD38,ARHGEF2,CHN2,OSBPL3,CX3CR1,RIPOR2,PITPNC1,ZEB2,SRGAP3,CPEB2,DOCK2,FAM78B,TSPAN5,FRY,TNK2,CERCAM,NCALD,RASL12,EYA1,ST3GAL6,OLFM1,AGAP2,FYN,STARD10,MALT1,PRRC2B,GP1BB,PADI2,KLF12,ZDHHC15,IRF8,ITGAM,JAK1,KLRC2,KLRC3,PIK3AP1,TM6SF1,STK32C,PDE2A,PFKP,CDK14,ABCB1,SSH1,PLTP,PPP3CC,SYTL2,SIDT1,CASTOR1,OXR1,ATP8B4,PRR5L,KCNIP3,PEAR1,SELL,RASA3,SGK1,ELMO2,TNIK,KIF21B,RAP1GAP2,ST5,FCHO1,SULF2,GSE1,ACSBG1,SEMA4A,KLHL4,AKNA,FRYL,PIK3R5,WBP2,TRIO,MICAL1,LAT2,ZBTB16,TMEM163,PLSCR4,ADAMTS10,SPATA13" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k1_1000 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 5.65E-03 1.00E+00 1.92E-02 1.75E-01 59 261 "ABCF1,ACTN2,KDM5D,ARID1A,ADD1,NR0B1,SEMA7A,GAS7,ARHGDIG,DDX3Y,MMD2,BTRC,CBLN1,QKI,COL9A3,RBM39,PPP1R16B,PLCXD3,PUM1,RIPOR2,MATR3,ZEB2,DTNA,PHF20L1,PLXNC1,PTK2B,FYN,MTHFD2,CSDC2,ZNF638,GPR37,KCNH1,MEF2C,MTR,MYH6,NFIA,PAK3,PLTP,RC3H2,SH3KBP1,PPP2R5E,PTPRE,MEG3,SFPQ,ARX,WDR37,PKNOX2,EFHD1,SMARCA4,ZCCHC24,ADHFE1,TACC1,OBSL1,LEFTY2,HHIP,TNS1,NR2C2,UBTF,STOX2" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.65E-03 1.00E+00 1.92E-02 1.75E-01 59 261 "MTUS1,LRRC7,SPARCL1,LARGE1,SLIT2,CRHBP,CREB5,ATRNL1,VCAN,CST3,PLCXD3,BRINP1,DCC,GRIN3A,DRP2,EDNRA,TMTC1,EGFR,LRRC17,EFEMP1,RACK1,ATP8A2,FREM1,ADAMTS6,KLF12,HPSE2,IGF1,KCNMA1,INSYN2,MATN2,MEIS1,MEIS2,MMP16,NTRK2,DDR2,PDGFRA,ENPP2,PENK,PFKFB2,PCDH18,PMP22,PRRX1,FAT3,NKAIN4,MASP1,PTN,TMEM255A,C1orf54,FAT4,LGI2,ROBO2,HUNK,PALLD,SULF2,ADGRL3,TEK,ASXL3,VLDLR,ADAMTS9" Coexpression Atlas PCBC_ratio_ECTO cord blood_vs_ECTO blastocyst_cfr-2X-p05 ECTO cord blood_vs_ECTO blastocyst-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 5.66E-03 1.00E+00 1.92E-02 1.75E-01 31 120 "PRX,LGI1,CACNG7,EFNB3,LRRC17,ST6GALNAC3,DNER,RND1,GPM6B,GRIA1,NKD1,FGFBP3,MN1,NEFM,NPY,KCNK10,PTH1R,RFX4,DRAXIN,SOX1,ZNF423,LRRC4,FCHO1,RGL1,PLCB1,ROBO3,KLHL4,PCDHGA10,RFTN2,ZIC3,FAM13C" Coexpression Atlas ratio_DE_vs_SC_500_K1 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1 PCBC 5.76E-03 1.00E+00 1.95E-02 1.78E-01 81 377 "KCNH8,SORCS1,ERMN,MTUS1,NR0B1,ARHGAP20,PCDH10,TRMT9B,LGR5,SLC7A14,ARSE,FGF17,CFLAR,C5,IL33,CCKBR,CDH2,CDH10,COL9A2,TENM4,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,C8orf34,SPOCK3,LPAR6,DLC1,AMOTL2,C1orf61,RASL10A,TBR1,CHL1,FREM1,PCDH17,FAM222A,HAS2,KCNF1,CLVS2,MATN3,LRP1B,MOBP,SAMD5,NBL1,NODAL,OLR1,SERPINE2,PDZRN4,PACSIN1,RASGEF1B,RELN,ELOVL2,ACSS3,FAM184A,PRIMA1,RXRG,CCDC92,SOX5,MCF2L2,NFASC,EPB41L3,SULF2,TMEM150C,ZFPM2,LEFTY2,HHIP,PIK3R5,SEZ6L,TRPM2,CADM1,RPRM,PDIA2,FLRT2,KCNK12,FMN2,ANKS1B,MEIS3,ADAMTS9,PLSCR4" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K1 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 5.88E-03 1.00E+00 1.99E-02 1.81E-01 33 130 "ACTN2,TBC1D14,APOC2,ARRB2,DACT3,ZNF599,SUMF2,CRY2,ELN,NCALD,CDKL3,HPCAL4,FYB1,GSN,LIX1,GPR155,MID1,BCO1,CLEC9A,ETFRF1,PILRA,CYBC1,STRC,REV3L,KCNIP3,RXRA,DOCK10,PEX26,C11orf87,PDLIM2,TMOD1,LAMP5,PMEPA1" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-3_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 5.88E-03 1.00E+00 1.99E-02 1.81E-01 49 210 "NDRG2,SPARCL1,LTBP4,TMEM263,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,BSCL2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,CCDC80,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,PREX2,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP,TUBA1A,ST8SIA2" Coexpression Atlas gudmap_developingGonad_e18.5_ovary_200_k3 DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.89E-03 1.00E+00 1.99E-02 1.81E-01 10 26 "BACH1,CHM,RBM39,LPAR4,CHIC1,TMLHE,FNIP1,SYNE2,SSBP2,ADAMTS9" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_100_k3 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 5.95E-03 1.00E+00 2.01E-02 1.83E-01 12 34 "BCHE,VCAN,DLC1,GABRB1,PCDH11X,NAP1L2,SOX5,PEG10,NSD1,ERCC6L2,RBFOX2,RGMB" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_200_k2 DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 5.95E-03 1.00E+00 2.01E-02 1.83E-01 12 34 "AMPH,CRYM,ELAVL4,CDHR1,EYA1,FAM19A2,FAM107A,HAS2,NELL1,SALL1,MAPK12,ANKRD6" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K3 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 5.96E-03 1.00E+00 2.01E-02 1.83E-01 34 135 "KDM5D,CDK10,DACT3,CRLF1,PCYT1B,CDON,DUSP9,ABCC9,ETV1,TMEM132C,ST6GALNAC3,ZNF276,HPSE2,SYNPO,IGF1,IL11RA,LAMA2,MBNL1,SRSF12,RSPO2,PCSK5,PDE3A,ZFHX4,TMEM100,DOCK10,NTNG1,PREX2,LIMCH1,TAF9,ASXL3,AMACR,TRPS1,CA14,TTPA" Coexpression Atlas gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k1_1000 dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 5.96E-03 1.00E+00 2.01E-02 1.83E-01 34 135 "SPARCL1,SEMA6A,BIN1,LCORL,APAF1,UPRT,SPAG9,LDB2,ZNF521,CEP170,DLC1,CHST15,ST6GALNAC3,NEK6,ZDHHC15,IGF1,MEST,LAYN,OPHN1,PALM,GNG2,SYTL2,SEMA6D,SMTN,PEG10,ZNF423,RGL1,ARHGEF9,TCF4,ZEB1,TUBB2A,ZNF711,PMEPA1,STOX2" Coexpression Atlas GSM399440_500 "B cells, B.FrF.BM, CD19+ IgM+ AA4.1- HSA+, Bone marrow, avg-3" "Immgen.org, GSE15907" 6.03E-03 1.00E+00 2.03E-02 1.85E-01 79 367 "ADD3,SNX30,ADRB2,ZNF608,TXNDC16,BCAR3,CARNS1,FGD2,DGKD,ATP6V0A1,BTK,CACNA1I,CACNA1E,CAMK2D,HIP1R,CD38,CDC25B,LY86,CNN3,SLC4A7,CSNK1G3,PPP1R16B,KIAA0040,RUBCN,CYBB,HDAC9,RIPOR2,GUCD1,SLC12A6,EBF1,SNX29,FRY,SRPK3,DENND4A,TLR7,CHST15,HVCN1,MALT1,RAB30,DCLK2,EML4,CECR2,RAPGEF4,ADAMTS6,IRAK3,BACH2,IRF8,IL12A,LMO2,PIK3AP1,GPR155,MEF2C,CD200,MYO5A,PPP3CA,PPP3CC,RASGEF1B,PRKCB,SIDT1,PXK,MARCH1,BEND5,LRRK2,SELL,RASA3,SH3BP2,ST6GAL1,LMBRD1,ARHGAP26,STAC2,MGRN1,TCF4,CYB561A3,C9orf85,LAT2,SIGLEC10,TMEM163,PLD4,PHTF2" Coexpression Atlas gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k5 DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.07E-03 1.00E+00 2.04E-02 1.86E-01 7 15 "CNTN1,DACH2,CLDN11,PCDH9,PTX3,VWC2,SYNPO2" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_500_k3 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.07E-03 1.00E+00 2.04E-02 1.86E-01 7 15 "ELAVL2,TUBB2B,NNAT,SNRPN,SOX2,RBM26,PCBP4" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Early fibroblastic progenitor Lungmap Mouse Lung E16.5 Proliferative fibroblast Subtype Early fibroblastic progenitor Lungmap CCHMC 6.10E-03 1.00E+00 2.05E-02 1.87E-01 90 426 "NCKAP5,ERMN,MTUS1,KLHL13,LTBP4,PARG,APOC1,CACNA1D,CARS,CBR1,CDO1,RAB28,ABI3BP,AKAP12,LRIG1,DOCK4,HDAC4,FBXL5,DDX46,DNM1,RCAN1,DYRK1A,COPS4,PCOLCE2,LRRC17,RASGRP2,CLVS1,TUBA1B,CHST15,FHL1,FOXM1,CINP,PNMA2,STAG2,ZMYND11,GFRA2,KIRREL3,TCERG1,GLI2,PSRC1,PTPN5,PSIP1,GYG1,ARHGAP19,HSP90AA1,MAT2A,MEIS1,MEST,KITLG,PTOV1,MYO6,NDP,NEK1,NFIA,NRCAM,PBX1,PFKFB2,GPSM2,FXYD1,SCHIP1,SEPT4,LRRN3,KANSL1,NKAIN4,PRPSAP2,ZCWPW1,ARID4A,RBBP8,ERI2,SEC61A2,RORB,RMI1,SEC31A,ABLIM3,SLC1A3,PREX2,SLC12A2,LIMCH1,PDLIM2,TCF4,TCF12,PUM2,TMPO,TNS1,TRO,RFTN2,FTSJ1,MAP3K12,CAMK1G,IFT88" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k4 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.10E-03 1.00E+00 2.05E-02 1.87E-01 44 185 "SLITRK1,PDE8B,PROM1,BMP7,BMPR1B,CALB1,CRLF1,B4GALT6,SLIT2,COL9A3,IPCEF1,CNTNAP2,KIAA0040,CTNND2,DUSP9,EMX2,SPSB4,FGF12,RASL10A,GFRA1,MAP7D2,GRIK2,FRMD5,L1CAM,KITLG,MYH7,VWA2,MAPK4,LAMA1,EML5,RASGRF2,RET,PRR5L,FHOD3,FAM81A,LIMCH1,LRRC4,TMEM150C,WWC1,WSCD1,DCBLD1,RPRM,VSNL1,EMX2OS" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_100 dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 6.16E-03 1.00E+00 2.07E-02 1.88E-01 22 78 "SHTN1,LGR5,PPP4R4,CACNA1D,PLXNA4,DOCK4,DRP2,EMX2,NRN1,GABRA4,GATM,PLD5,KLHL23,KITLG,PCDH18,GDPD2,TMEM206,TNFRSF19,SLC4A3,ADAMTS17,ADGRL3,ACTR6" Coexpression Atlas ratio_SC_vs_MESO_1000_K2 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 6.16E-03 1.00E+00 2.07E-02 1.88E-01 29 111 "ADD2,OLMALINC,ANK1,DOCK11,CA8,RAB33A,TJP2,PCYT1B,ARRDC4,RASGRP2,CDHR1,AGAP2,IQGAP2,ACSS1,NEU3,LOXL3,TDRKH,SCIN,KHK,PIK3AP1,PPM1L,BLOC1S2,ALDH1L2,PRKCB,ACSBG1,SPX,TMEFF2,VAV1,TMEM163" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k1_1000 dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.33E-03 1.00E+00 2.12E-02 1.93E-01 18 60 "NCKAP5,GRAMD1B,APOC1,DDX3Y,CBLN1,SCARB1,ARMCX2,TMEM164,KLF12,PLTP,ROBO2,ITPRID2,ACSBG1,TGFBR3,HHIP,HEY2,VSNL1,STOX2" Coexpression Atlas gudmap_developingKidney_e15.5_S-shaped body_1000 DevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.44E-03 1.00E+00 2.16E-02 1.97E-01 160 811 "PLEKHH1,GRAMD1B,ADORA1,PCDH19,NR0B1,DOC2A,APBB2,EPB41L5,DGKD,LGR5,CDC14B,ASPA,CCAR2,NRP2,PROM1,BMP7,CA4,CA12,CACNA2D1,CANX,HIP1R,MAP7,CLDN10,CD38,LRBA,CACNA2D2,SLC22A6,CLU,RBM39,TENM4,LRIG1,KIAA0040,CTH,GREB1,ARHGAP24,SCRN1,AIF1L,SMG7,NTM,TMCC2,KBTBD11,DUSP9,HIPK3,HEYL,EIF5,EIF1,EMX2,EPB41,RASGRP2,EPHB1,CD320,ST3GAL6,MED12L,SPSB4,FGFR1,FOXO3,FLT1,ANKFY1,SGIP1,SMC2,RASL10A,CGREF1,FUT9,PHYHIPL,ILDR2,GALC,SALL3,SYT17,IGSF5,GCNT2,PCDH17,PPARGC1A,GK,AIFM3,CBX1,KCNMB4,ADGRA3,B4GALNT4,GPER1,GRB10,PARD3B,TMEM25,FAM107A,HP,IGSF1,SCIN,HES5,KCNC2,KCNJ5,KCNJ16,TTYH2,LIFR,GPR155,CLEC18A,AQP11,TM6SF1,KITLG,FXYD6,NCAM1,VWA2,NRCAM,OXTR,ENPP2,PIK3C2A,RETREG1,PLXNB1,ANKRD16,SCHIP1,MBOAT7,POLG,IRX1,KANSL1,PKN2,MAPK4,MAPK8,RELN,CNNM2,LAMA1,ELOVL2,PTPRO,RIPOR1,NKAIN1,ZDHHC14,DPF2,EMID1,LGR4,SALL1,SCN8A,LINC00461,HES6,ZNF821,FHOD3,FAM81A,DHX30,SLC9A5,MYCBP2,DDN,ZSCAN29,APOM,STX1A,TMEM150C,TAF9,DNMBP,CAMSAP2,WWC1,WSCD1,SIN3B,SATB2,HEY1,ZFP91,ERCC6L2,RGMB,ELP5,DCBLD1,CA14,ZNF23,GDPD5,TMEM178A,FIP1L1,SPATA13" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_100 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_100 FaceBase_RNAseq 6.44E-03 1.00E+00 2.16E-02 1.97E-01 26 97 "GPRASP2,CA4,CDO1,CRLF1,LHX2,IGDCC3,CREB5,HAPLN1,ELN,CECR2,GSN,SYNPO,ZIC5,IL11RA,NFIA,NFIX,NNAT,PRTG,IRX1,ZMAT4,SALL1,SOX10,ZIC1,ZIC2,PMEPA1,SENP7" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_1000 DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.46E-03 1.00E+00 2.16E-02 1.97E-01 151 761 "ACADM,ADORA1,ALAD,AMPH,EPB41L5,USP37,LGR5,ASPA,DYNLL1,ALDH4A1,ATM,ATP1A1,BMP7,CA4,CA8,CA12,CALB1,MAP7,CLDN10,SLC22A6,CLU,CLTA,NIPBL,RBM39,OSBPL3,PPP1R16B,KIAA0040,GREB1,ARHGAP24,ACY3,SPOCK2,DDX46,GUCD1,FAM107B,KBTBD11,DUSP9,ABCC9,EDNRB,SGK2,MBNL2,EIF5,EMX2,HSD17B14,EPS8,PIPOX,FABP7,ST3GAL6,FGF1,FGFR1,FGFR3,FHL1,FOXO3,SEMA4D,ATP13A4,SMC2,PDLIM5,KHDRBS3,CELF1,CGREF1,FUT9,ILDR2,SALL3,MTHFD2,ACSS1,IGSF5,ALDH1L1,PPARGC1A,GK,CBX1,GPD1,GPM6A,CIT,TMEM25,AP4S1,GUCY1A1,GUCY1B1,IDH3A,IGFBP1,SCIN,HES5,ITGAV,JAK1,KCNC2,CLEC18A,AQP11,TM6SF1,MEF2C,MITF,MYO6,NPY,NRDC,OXTR,PALM,CYTL1,PFKP,RETREG1,SCHIP1,IRX1,PPP5C,LAMA1,PTH1R,ELOVL2,PTPN13,PTPRG,PTPRO,PLEKHB2,ZDHHC14,RDX,RET,TMEM100,EMID1,SGK1,KIF21A,SH3GL2,DOCK10,SHMT2,FHOD3,SLC15A2,EFHD1,SLIT1,SMARCA4,LIMCH1,EMC1,DDN,LARP4,APOM,RGL1,PRRC2C,SYPL1,COBL,CAMTA1,WWC1,SATB2,TRIM2,WASHC4,HEY1,CBX5,TPD52,NPL,AMACR,TST,SGK3,UGT8,SF1,ZNF24,SPIRE1,EVI5,STOX2,TMEM178A,VPS35L,SPATA13" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ bladder_100 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 6.53E-03 1.00E+00 2.18E-02 1.99E-01 23 83 "MYOM1,BCHE,NRP2,VCAN,EPHB1,DLC1,PNMA2,MEGF10,GABRB1,PCDH11X,IFI16,NAP1L2,HCN1,SOX5,PEG10,C11orf87,NSD1,ERCC6L2,RBFOX2,RGMB,SYNPO2,ACTR3B,MSRB3" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k2_1000 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.55E-03 1.00E+00 2.19E-02 2.00E-01 32 126 "ABAT,CDC14B,DCT,POM121,SRGAP3,PLXNC1,SORBS3,FAM198B,EVL,AFF2,CAMKK2,GPR37,BVES,SHISA6,TUBB2B,KCNH1,KCNH2,CTNNA3,RASGEF1B,PRKCB,PTPN13,ROBO1,TMEM206,SOX6,MRAS,ST6GAL1,ST8SIA1,TSPYL2,SMOC1,OBSL1,ZFPM2,WNK3" Coexpression Atlas gudmap_developingKidney_e15.5_500_k3 DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.59E-03 1.00E+00 2.20E-02 2.01E-01 47 201 "RALGAPA1,ABHD6,BEND6,ANK3,APC,EPB41L5,DGKD,TNRC6C,SLC4A4,CACNA2D1,CANX,CLCN3,NCOR1,ARNT2,DNM2,GOLT1B,MED12L,SYNCRIP,SMC2,PPARGC1A,KIF2A,CHIC1,MKLN1,NCAM1,CNOT4,PENK,PFKP,PRRX1,KANSL1,MAPK8,RASGRF1,REV3L,ZFP2,FAM126B,ZHX3,MYCBP2,PRRC2C,CAMSAP2,MGRN1,ZFP91,ERCC6L2,RBFOX2,RGMB,SSBP2,VLDLR,ADAMTS9,DOCK8" Coexpression Atlas gudmap_kidney_adult_RenCorpuscGlomer_500 kidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.60E-03 1.00E+00 2.20E-02 2.01E-01 92 438 "CPNE2,HECW2,C1QTNF1,ADGRF5,PI16,UPRT,B3GALT2,CFLAR,CALB1,THSD7A,CD38,MYOM2,CLTB,ARHGEF6,CP,ANKRD44,CSF1,CYBB,ARHGAP24,DGKB,AIF1L,MAGI2,EBF1,EDNRB,TMTC1,OPTN,CALCRL,RCAN2,TLR7,F8,DLC1,ST3GAL6,FGF1,FLT1,SGIP1,UFM1,ST6GALNAC3,ILDR2,GALC,IQGAP2,ERAP1,INPP5K,RAPGEF4,STMN2,PARD3B,NR3C1,GUCY1A2,GUCY1A1,SYNPO,LIFR,LMO2,CCDC80,MYO6,PDE2A,SERPINE2,SERPINI1,PLCL1,SEPT4,SLC36A4,MINDY2,PKIA,SNRK,PTH1R,PTN,PTPRB,PTPRO,RIPOR1,RAVER2,ROBO2,SCN7A,SGK1,DOCK10,FAM81A,PREX2,SLC12A2,CPEB4,LMBRD1,COLGALT2,ITPRID2,PLCB1,TMEM150C,SYNE1,TNS2,FRYL,TEK,TLR4,DAAM2,TRPC1,PLEKHH2,SLC26A10,PLSCR4,CERS6" Coexpression Atlas gudmap_kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_Scamp_k1_1000 kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.67E-03 1.00E+00 2.23E-02 2.03E-01 99 476 "DPF1,RBM10,EMILIN3,ELFN2,PWWP2A,ADRA1D,DOC2A,LRFN1,ANK1,PPFIA4,SUGT1P4-STRA6LP-CCDC180,AMER3,DACT3,ATP1A3,BAIAP3,CDK5R2,CACNG1,THSD7A,SYT6,P2RX6,CBFA2T2,GPR37L1,CBARP,QKI,IGLON5,COL9A2,COL9A3,COL11A2,FAM171B,ARHGEF4,HDAC9,ARHGAP32,TOX,GRIN3A,HS3ST2,MAMLD1,DYRK1A,FAM135B,EGR3,DENND4A,REEP2,GTF2IRD2,FOXG1,NKX6-2,GRIK5,SERP2,SLC2A6,TMEM179,WIF1,IGFBPL1,LRRC75A,BTBD17,ITPKA,KCNB1,PPM1L,MMP16,MMP17,MYO9A,NCF2,GPR88,PDYN,SNX10,NXPH1,POU3F2,VSTM2L,KIF7,PAQR6,NTNG1,SNCB,MAPKBP1,TMCC1,SOX3,LHFPL4,ARHGAP26,NFASC,SST,SSTR1,LRRC4,SYNE2,ADAMTS17,SYT4,SZT2,TIAM1,TNS1,CHST5,ZNF384,TRH,TRIO,FLRT1,PLEKHH2,MGAT5B,PLPPR2,REEP1,SLC30A3,GDPD5,STMN4,ADAMTS9,SLC17A7,WNK2" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k3_500 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.72E-03 1.00E+00 2.24E-02 2.04E-01 34 136 "KCNH8,PCDH19,B4GALT6,SLIT2,HAPLN1,FAM169A,CTNND2,TOX,DUSP9,PLEKHA1,EMX2,EN2,GAP43,MAP7D2,GNG3,GRIK2,HMGB1,LIX1,KIT,TCEAL5,FAT3,EML5,PTPRZ1,TMEM255A,RET,MORC4,NUDT11,BEX1,SYT11,NUDT10,BEX4,UCHL1,VSNL1,SOCS4" Coexpression Atlas gudmap_RNAseq_p2_CD2APMEISWT_2500_K1 gudmap_RNAseq_p2_CD2APMEISWT_2500_K1 Gudmap RNAseq 6.72E-03 1.00E+00 2.24E-02 2.04E-01 167 851 "ACADM,AS3MT,C3orf14,ADORA2A,ESYT2,PI16,MAP4K3,ANXA7,APBB2,FAM131A,ARNTL,MARK4,ATP1A1,ATP1B3,ATP6V1G2,CFLAR,KSR1,ST3GAL5,RAB29,LDLRAD4,CACNA1A,CAST,ARHGEF25,FMNL3,CD81,LRRFIP1,CHN1,PPT2,STOML1,CLTB,QKI,TMEM184B,AKAP7,CABP1,IFFO1,PNKD,CLOCK,ANKRD44,ABCG1,CSF1,SOCS5,USP6NL,HDAC9,MYADM,RIPOR2,IP6K1,PITPNC1,RUSC2,DMPK,MAMLD1,FIS1,TSPAN5,TMTC1,GOLGA7,IRAK4,EML1,CALCRL,EPB41L2,EPHB1,EPS8,NCALD,CEND1,TAOK3,DLC1,TOMM40L,VTI1B,SORBS1,CAMKK2,SARAF,TMEM151A,ERAP1,NTNG2,FUT10,RAPGEF4,SERP2,ATE1,COQ10A,IRAK3,RASSF8,KLF12,GABARAPL2,LRRC75A,ITGAV,ITPKB,JAK1,JAK2,KIFC3,LAMP2,CAMK2N2,LIFR,VWA5A,MAN2A2,MBNL1,MEF2C,CD200,LAYN,IDNK,NTRK3,OGG1,PDE4A,SSH1,CCSER2,PKD1,SPATA6,SH3KBP1,SNRK,TMEM104,PXK,PTPRB,PTPRG,ZSCAN2,RAB3A,RAB5B,C1orf54,RASGRF2,RGS3,PRR5L,PTGR2,MAPK12,ATXN1,FAM19A1,GALNT10,RASA3,SGK1,SH3BP2,EPN2,SMTN,LIMS2,SLC12A4,ELMO2,ABTB1,LMBRD1,FAM219A,ARHGAP26,SPTAN1,IQSEC2,CDK19,CAMTA2,ST5,MPRIP,SEPT8,STXBP1,C3orf70,TACC1,ADGRL3,TBCEL,SYNE1,CYB561A3,TEK,CHST8,THRA,ENHO,NACC2,TK2,TPM2,RFTN2,UBC,UBE2H,VAV2,TOM1L2,CLIP2,NPDC1,ZFAND5,SHD,ITM2C,PLSCR4,PIANP" Coexpression Atlas gudmap_developingKidney_e15.5_stage III -IV renal corpusc_500_k2 DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.75E-03 1.00E+00 2.25E-02 2.05E-01 44 186 "KLHL32,SEMA7A,EPB41L5,OSGIN2,THSD7A,HIP1R,ARHGAP24,AIF1L,MAGI2,NTM,TMCC2,OPTN,SRPK3,CDHR1,ST3GAL6,SGIP1,CGREF1,GABRA4,ILDR2,IQGAP2,IGSF5,GGT5,PARD3B,GRM7,SYNPO,HP,MAPT,SYT9,LYRM9,SERPINI1,RETREG1,SCHIP1,MBOAT7,PTPRO,RIPOR1,FAM184A,DUSP15,ROBO2,ANKRD6,DDN,STX1A,TMEM150C,PDLIM2,TMEM178A" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_1000 dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.75E-03 1.00E+00 2.25E-02 2.05E-01 44 186 "ACHE,RNF157,BIN1,APBB1,APLP1,ARHGDIG,ASCL1,ATP1A3,CBARP,CLTB,PICK1,CNTFR,SLC35F1,SDC3,CMTM5,CEND1,TUBA1B,NELFCD,DPYSL4,GFRA2,GP1BB,B4GALNT4,TUBA1C,ACOT7,INSM1,TUBB2B,KLC1,LMO1,TAGLN3,NPY,FXYD1,POLR2F,PSMD13,ELOVL2,RAB3A,S100B,ASRGL1,CCDC92,SOX10,KIAA0930,THRA,UCHL1,MEIS3,MVB12B" Coexpression Atlas GSM538291_500 "NK cells, NK.b2m-.Sp, NK1.1+ TCRb-, Spleen, avg-3" "Immgen.org, GSE15907" 6.75E-03 1.00E+00 2.25E-02 2.05E-01 83 390 "AS3MT,GRAMD1B,ADORA2A,ESYT2,HACE1,KCNAB2,GAS7,CDC14B,ATP1B3,BAIAP3,CAMK2B,CHN2,ABCG2,OSBPL3,IPCEF1,CX3CR1,RIPOR2,PITPNC1,SRGAP3,RABGAP1L,DOCK2,DENND4A,RASL12,EYA1,ST3GAL6,FER,OLFM1,NPTN,ZNF512,FYN,CAB39,MALT1,PADI2,KLF12,IRF8,ITGAM,JAK1,KLRC2,KLRC3,PIK3AP1,TM6SF1,STK32C,MYO6,PDE2A,PFKP,CDK14,ABCB1,SSH1,PIK3R1,PPP3CC,PRKACB,SYTL2,SIDT1,FAM184A,OXR1,RAVER2,ATP8B4,PRR5L,KCNIP3,SATB1,PEAR1,SELL,FAM102A,ELMO2,TNIK,KIF21B,ARHGAP26,KIF1B,RAP1GAP2,ST5,SULF2,SEMA4A,KLHL4,TCF7,GPRIN3,FRYL,TRIO,MICAL1,WIPF1,LAT2,TMEM163,PLSCR4,SPATA13" Coexpression Atlas gudmap_developingGonad_P2_epididymis_1000_k5 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 6.77E-03 1.00E+00 2.25E-02 2.05E-01 35 141 "ADD3,WDR35,TAOK1,C1QTNF3,SPARCL1,ARHGAP20,LTBP4,PTCH2,DDX3Y,ATP1A2,JAZF1,CP,PLCXD3,RIPOR2,ELN,LRRC17,CSDC2,LAMA2,VWA5A,MAOB,MATN2,MEF2C,NRBP2,NDP,NFIA,NFIX,CLDN11,FXYD1,TACC1,HHIP,RASD2,NPL,NR2C2,PMEPA1,SSPN" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_1000 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 6.81E-03 1.00E+00 2.26E-02 2.06E-01 21 74 "ADGRF5,SPARCL1,SEMA6A,LCORL,BACH1,LDB2,ZNF521,HAPLN1,PLEKHO1,GAP43,LPAR4,LIFR,POC1B,GNG2,MDGA2,TMEM255A,PEG10,KLHL4,TEK,FLRT2,ZNF711" Coexpression Atlas adipose tissue adipose tissue Human Protein Atlas 6.87E-03 1.00E+00 2.28E-02 2.08E-01 39 161 "C1QTNF1,SRPX,ABCD2,GYG2,CALB2,CNTFR,PLXNA4,SLC29A4,EBF1,PCOLCE2,TMEM132C,GALNT15,GHR,LYVE1,GPD1,ATOH8,HAS2,ITGA7,C2CD4C,KCNB1,NAT8L,MDFI,MT1M,PDE3B,PLIN1,PPP1R1A,PTX3,KCNIP2,S100B,SCN4B,MESP1,ARC,TBX15,SLC19A3,SPX,THBS4,TIMP4,KCTD2,PRRT4" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k4_200 dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 6.90E-03 1.00E+00 2.29E-02 2.08E-01 17 56 "MYRF,CALB1,CDH10,ATRNL1,NKD1,KCND2,MATN2,MEIS1,CCDC80,NEFM,NFIA,PDE1A,PCDH18,PRRX1,ZFPM2,ASXL3,DAAM2" Coexpression Atlas GSM538285_500 "NK cells, NK.49CI+.Sp, NK1.1+ CD3- Ly49C/I+, Spleen, avg-3" "Immgen.org, GSE15907" 6.92E-03 1.00E+00 2.29E-02 2.09E-01 82 385 "AS3MT,ADORA2A,KCNAB2,GAS7,CDC14B,BAIAP3,CD38,CHN2,ABCG2,OSBPL3,CX3CR1,RIPOR2,TOX,ZEB2,SRGAP3,DOCK2,FAM78B,TSPAN5,TNK2,DENND4A,NCALD,RASL12,EYA1,ST3GAL6,FER,OLFM1,FYN,CAB39,GP1BB,PADI2,KLF12,ZDHHC15,IRF8,ITGAM,JAK1,KIT,KLRC2,KLRC3,TM6SF1,STK32C,MYO6,PDE2A,PFKP,CDK14,ABCB1,SSH1,PIK3R1,PPP3CC,PRKACB,SYTL2,SIDT1,FAM184A,OXR1,ATP8B4,PRR5L,KCNIP3,SATB1,PEAR1,SELL,ELMO2,SMARCD3,TNIK,ARHGAP26,KIF1B,RAP1GAP2,ST5,SULF2,SEMA4A,KLHL4,TCF7,GPRIN3,FRYL,CDH22,TLR4,TRIO,RUNDC3B,MICAL1,LAT2,TMEM163,PLSCR4,MARCH8,SPATA13" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k2_500 kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 6.95E-03 1.00E+00 2.30E-02 2.10E-01 19 65 "NDRG2,SPARCL1,ALDH7A1,MYOM1,CACNB2,DCLK1,CCDC3,DMD,EDIL3,EDNRA,TUBA8,TCEAL6,LRRTM3,MEF2C,FIGN,RERGL,SLC4A3,HEY2,TPM2" Coexpression Atlas Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K4 FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 6.98E-03 1.00E+00 2.31E-02 2.11E-01 69 316 "NDRG2,PLEKHG5,PTCHD1,MTUS1,C1QTNF1,KCNAB2,APOC1,CACNA1B,MAP7,CBARP,MYL6B,LETMD1,SPOCK2,C8orf34,RABGAP1L,SEMA3D,EFNA3,EGFR,RRAGB,FGF12,SEMA6C,SEMA4D,STAMBP,TPPP3,GAA,GAD2,STARD10,PCDH17,GLRB,PCDH11X,NR3C1,FAM107A,FRMD3,LRRC75A,KCNK1,MAOB,IL17D,MEIS1,SRSF12,MOV10,SAMD14,HS6ST3,GPR173,SERPINE2,SMOX,FXYD1,NECAB2,RAB3A,LGR4,FERMT1,CCDC92,CLSTN1,DOK5,UNC5B,INKA2,ZFR2,WWC1,WSCD1,TEX15,SLC44A1,TNNT1,CA14,CADM1,TOM1L2,PORCN,NDRG4,SH3GLB2,NAV3,TMEM163" Coexpression Atlas Facebase_ST1_e9.5_OticVesic_500 e9.5_OticVesic_top-relative-expression-ranked_500 FaceBase_ST1 7.05E-03 1.00E+00 2.33E-02 2.13E-01 84 396 "SDE2,MTUS1,AMT,PKP4,PDXK,ATP1A1,FGF17,BMP7,RAB29,CA4,CLDN10,USP2,CDH2,CDO1,SOCS6,VAX2,PICK1,COL9A1,COL9A3,GAL3ST1,CSNK1E,CMTM5,SCRN1,OLIG1,PCOLCE2,HSD17B14,EYA1,C15orf41,STARD10,GBX2,GJB1,ZNF276,GLDC,KCNMB4,CACFD1,RNF165,IGFBPL1,NKD1,KCNK1,AQP11,MDFI,KCTD6,MITF,AFF1,LYRM9,NEUROD1,NPY,SLC11A2,PAX6,ENPP2,PLCD1,PLP1,SLC25A23,SCHIP1,PPP2R2B,PRKCZ,FIGN,SETD5,EMID1,PTGR2,SH3GL2,ARFGAP1,CMTR2,SOX2,SOX10,SPP1,SPART,ADAMTS17,MTCL1,WSCD1,KIAA0930,MTMR14,HEY2,TPD52,TRIO,RPRM,SLAIN1,XRCC4,ZFAND5,LMAN2L,URM1,SNX27,PDSS2,NETO2" Coexpression Atlas JC_iEC_1000 JC_iEC_top-relative-expression-ranked_1000 PCBC 7.15E-03 1.00E+00 2.36E-02 2.15E-01 191 987 "ASIC2,EMILIN3,FAM43B,PLEKHG5,ADCY2,GALNT13,KIAA1211,ADRA1D,SLC44A5,HECW2,KLHL13,CASKIN1,PCDH19,KIAA1324,OSBPL6,MARCH4,PCDH10,BBOX1,AMH,SEMA7A,PI16,SLC7A14,INSYN2B,TMEM108,AZGP1,ST3GAL5,MYRF,CACNA1E,CALB1,THSD7A,HAP1,SYT6,CH25H,NEURL1,DGKI,LONRF2,CDH10,LGI1,DLGAP1,NOG,SYNPR,JAM2,TMEM155,AKAP5,HS3ST5,CRYBB1,RIPOR2,AIF1L,DCC,C8orf34,CNIH3,MFAP3L,GRIN3A,CPEB2,DPP6,MAMLD1,EBF1,TMTC1,TENM1,CALCRL,EN2,SEZ6,CDHR1,PIPOX,HSPA12B,F3,FGF12,FOXG1,ATP13A4,PNMA2,HHIPL1,NRG3,ILDR2,GAP43,DNER,IGSF5,GBX2,GGT5,PCDH11X,GNAO1,GNG4,LNX1,MCHR1,STMN2,GRM7,ZBTB49,BVES,LINGO1,MAEL,TOX2,ARHGAP36,MIER3,LRRTM3,KCND3,KCNF1,PIK3AP1,MATK,CHST6,SAMD5,MSR1,NCAM1,NCF2,NDP,NELL1,NPTX1,NRCAM,NTRK2,OPCML,OXTR,ZDHHC22,SNTG1,PCDH9,PCSK1,PCSK5,PDE3B,PDE4D,SLC10A4,PMP22,TRHDE,FA2H,SNRK,PTHLH,PTPRB,PTPRE,RIPOR1,SH3TC2,RNASE1,RPE65,TMEM100,EMID1,SOX8,SALL1,SCN3A,SCN8A,SELL,STUM,SGK1,ST6GAL1,PREX2,LIMS2,LRRC55,CXXC4,OGDHL,FAM126B,SOX1,SOX2,SPP1,ITPRID2,THSD1,RHBDL3,ARC,SYT1,POPDC3,KLHL4,ANO4,TBX15,VWC2,PCDHGB6,PCDHGB2,PCDHA6,SLC35G2,VWCE,TEK,ARL10,TIE1,ASXL3,TLL2,IL34,SYNPO2,TRH,TRPS1,NUTM2A,FNDC5,DCBLD1,UGT8,MGAT5B,VGF,VLDLR,VSNL1,KCNK12,TRIM9,LYPD6,CELF4,EML6,LAMP5,SLC30A3,TMEM178A,PCDH15,ZNF37BP,NETO2,ST8SIA2" Coexpression Atlas PCBC_ratio_ECTO blastocyst_vs_ECTO amniotic fluid MSC_cfr-2X-p05 ECTO blastocyst_vs_ECTO amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 7.16E-03 1.00E+00 2.36E-02 2.16E-01 64 290 "AXIN2,PCDH10,RASL11B,NRP2,LRBA,NOG,PLEKHB1,SLIT2,NGEF,IQCK,COL9A2,COL11A2,NRG2,HAPLN1,TENM4,PDE4DIP,LYPD1,ARRDC4,EDNRA,EPHB1,FABP7,TMEM132C,SCARA3,GAP43,ERAP1,LIX1,ITPKB,KCNA1,KIT,LRRC4B,VWA5A,CLEC18A,MATN2,MDFI,MEIS2,MPP2,DBNL,SAMD5,MYCN,TCEAL5,HNRNPM,NPY,PDE2A,PLEC,IRX1,ZFHX4-AS1,LRRN3,VSTM2L,PRODH,RELN,GDPD2,ZFHX4,MYH14,TNFRSF19,SLC30A10,SLIT1,DOK5,WWC1,IQCE,PCDHGA10,TMEFF2,LMF1,DOCK8,IFT88" Coexpression Atlas PCBC_ratio_MESO-5_from-ESC_vs_MESO-5_from-OSK-L-l-p53KD_cfr-2X-p05 Mesoderm Day 5-reprogram_NA_vs_Mesoderm Day 5-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 7.16E-03 1.00E+00 2.36E-02 2.16E-01 25 93 "KCNH8,LGR5,JAZF1,LARGE1,CRMP1,PPP1R16B,ERBB4,HRASLS5,FREM1,IGFBPL1,HP,KCNF1,KCNK1,NRCAM,TMEM100,RXRG,SLC6A9,PEG10,TMEM150C,KLHL4,LEFTY2,PIK3R5,KCNK12,FMN2,PMEPA1" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_500 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.18E-03 1.00E+00 2.37E-02 2.16E-01 30 117 "ZSCAN18,TMEM108,SLC4A4,MYRF,CALB1,CDH10,CNTFR,AKAP5,ZNF521,CLIP3,ATRNL1,DNM1,TSPAN5,FLNC,GUCY1A2,TCEAL6,NKD1,KCND2,MATN2,MEIS1,CCDC80,NEFM,NME4,PCDH18,PRRX1,PTN,KCNIP1,PALLD,ZFPM2,TRPS1" Coexpression Atlas gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_1000 dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 7.24E-03 1.00E+00 2.39E-02 2.18E-01 22 79 "KDM5D,PNMA8B,GRAMD1B,DDX3Y,SCARB1,FADS2,MICAL2,VCAN,CD99L2,PLXNC1,EYA1,FABP7,IQGAP2,SEPT9,LOXL3,PSRC1,MASP1,PTCH1,PTPRD,MEG3,SOX6,SYNE2" Coexpression Atlas Lungmap Mouse Lung E16.5 Proliferative fibroblast Lungmap Mouse Lung E16.5 Proliferative fibroblast Lungmap CCHMC 7.39E-03 1.00E+00 2.43E-02 2.22E-01 95 456 "CDC7,LTBP4,ANK2,LCORL,BLM,AP1M1,CACNB2,RUNX1T1,PRC1,RCBTB2,ABI3BP,SNCAIP,LRIG1,VCAN,DZIP3,CENPL,FBXL5,ARNT2,EDNRA,EDNRB,EFS,ETV1,TUBA1B,FOXF2,FOXM1,TMEM107,SMC2,NSG1,DKK3,GFRA2,FREM1,GHR,BRD8,DBF4,GPT2,PSRC1,PSIP1,GUCY1B1,GYG1,ARHGAP19,IGF1,KCNK3,LAMA2,STMN1,MEIS1,PTOV1,FXYD6,NASP,NCAM1,NDP,NRCAM,PBX1,PDGFRA,SERPINE2,ANLN,GPSM2,PCDH18,LRRN3,KANSL1,NKAIN4,PRPSAP2,CNTLN,PTCH1,PTH1R,SPDL1,ZCWPW1,ARID4A,RBBP8,ERI2,UBR7,ZFHX4,ROBO2,RORB,TMEM100,ZC3H14,ATAT1,SEC31A,DZIP1,EPC1,PALLD,PDZRN3,TTBK2,DNAJC9,HHIP,CBX5,TMPO,TNNT1,TPM2,TRO,STXBP4,VSNL1,PMEPA1,TUBA1A,CAMK1G,AAAS" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_1000_K1 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#1 FaceBase_RNAseq 7.39E-03 1.00E+00 2.43E-02 2.22E-01 58 259 "NDRG2,PTCHD1,MTUS1,ANK3,FGD2,APOC1,SNAI3-AS1,FGF17,CACNA1B,MAP7,CHN2,TJP2,ABCG1,SPOCK2,CDON,SEMA3D,EFNA3,EGFR,SLC43A2,EYA1,CLVS1,FGF12,ATP2C1,TPPP3,GAD2,STARD10,GCNT2,PCDH17,PCDH11X,KCNMB4,NR3C1,PSIP1,FAM107A,FRMD3,KCNK1,KIT,MAOB,IL17D,SAMD5,NECAB2,SUSD4,RAVER2,LGR4,HES6,FERMT1,CCDC92,KANK1,TEX15,HEY1,TNNT1,TPD52,CA14,CADM1,NDRG4,ADAMTS9,NAV3,NAV2,TMEM163" Coexpression Atlas gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k1 DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.41E-03 1.00E+00 2.44E-02 2.22E-01 32 127 "PCDH19,ADGRB3,BMPR1B,CCK,COL9A1,CRYM,SIPA1L1,GSDME,GRIN3A,EDN3,DPYSL4,TVP23A,GABRA1,B4GALNT4,GRIK2,HAS2,KCND1,MEIS1,COMMD5,PBX1,PCDH8,ING3,SALL1,MAPK12,HES6,ASRGL1,DHX30,RADIL,SLC9A5,ENHO,TPM2,NETO2" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_500 dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.42E-03 1.00E+00 2.44E-02 2.22E-01 26 98 "KDM5D,AMH,CADPS,CLU,MRO,PLXNC1,EPS8,FAM198B,PTK2B,FGF13,IQGAP2,GATM,PPARGC1A,ADGRA3,GPM6B,PAK3,SERPINE2,RASGEF1B,MASP1,ROBO1,GLDN,SOX6,DOCK10,THRA,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingGonad_e14.5_ testes_500_k5 DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 7.42E-03 1.00E+00 2.44E-02 2.22E-01 26 98 "AMH,SEMA7A,ST3GAL5,MMD2,DDR1,CBLN1,ADGRG1,CLU,FADS2,RCAN1,DTNA,EDNRA,PLXNC1,EPB41L2,GPM6B,GPR37,MYO7A,PAK3,PDGFRA,SEMA5B,MEG3,ARX,EFHD1,ACSBG1,HHIP,TST" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_200 dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.49E-03 1.00E+00 2.46E-02 2.24E-01 16 52 "NR0B1,DOCK4,DRP2,EMX2,NRN1,GABRA4,PCDH11X,KLHL23,KITLG,MYO9A,LGR4,SLC4A3,KDM3A,ADGRL3,TEX15,ACTR6" Coexpression Atlas gudmap_dev gonad_e11.5_F_ReproVasc_Flk_200 dev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.51E-03 1.00E+00 2.46E-02 2.25E-01 43 182 "HECW2,ADGRF5,NRP2,C1QC,LDB2,CD38,HAPLN1,ELMO1,CCDC3,EBF1,EDN1,EDNRB,CALCRL,FLT1,PDLIM5,FYB1,GAP43,PCDH17,LYVE1,HPGDS,LPAR4,RAPGEF4,ICA1,IGF1,LMO2,TM6SF1,MEF2C,PDE2A,PROX1,SNRK,MDGA2,PTPRB,TMEM255A,SGK1,PREX2,LIMCH1,THSD1,KLHL4,TEK,TIE1,TRPC3,TTPA,ZNF711" Coexpression Atlas GSM605883_100 "Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3" "Immgen.org, GSE15907" 7.51E-03 1.00E+00 2.46E-02 2.25E-01 20 70 "APOC2,ATP1A3,ZFYVE9,GDA,CSF1R,CX3CR1,CYBB,SIRPA,IGSF6,TLR7,SIRPB1,FCGR3A,FGR,ITGAM,LDLRAD3,PILRA,SLC11A1,SLC12A2,FGD4,PLD4" Coexpression Atlas GSM538412_500 "alpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1" "Immgen.org, GSE15907" 7.52E-03 1.00E+00 2.46E-02 2.25E-01 69 317 "EMILIN3,ACTN1,AXIN2,ESYT2,USP28,CDC14B,DACT3,ATM,ATP1B3,DOCK11,DLGAP1,CRLF1,IPCEF1,RIPOR2,TOX,KBTBD11,MED12,RASGRP1,KIAA1109,NSG2,GPR153,FYB1,RAPGEF6,RAPGEF4,WIF1,BACH2,AGFG1,IL6R,SLC35G1,KCNA2,NAT8L,MDM4,NEFH,NPTX2,ZNF827,PDE3B,SLC10A4,PACSIN1,SH3KBP1,PPP3CC,PRKCZ,SIDT1,PLPPR1,EML5,CEP97,REV3L,RAVER2,AMER2,SATB1,SELL,FAM102A,ST8SIA1,DZIP1,TET1,SOX3,TNIK,STX1A,PRRC2C,VPS13A,TCF7,GPRIN3,NR2E1,TNS1,TRIO,RUNDC3B,TTC3,RICTOR,PMEPA1,KLHDC1" Coexpression Atlas gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_100 dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 7.63E-03 1.00E+00 2.50E-02 2.27E-01 23 84 "NR0B1,SHTN1,LGR5,CACNA1D,PLXNA4,DOCK4,DRP2,EMX2,NRN1,GABRA4,GABRB1,KLHL23,KITLG,PDE1A,PCDH18,GDPD2,TMEM206,SLC4A3,SMOC1,ADGRL3,ACTR6,FNDC5,WNK3" Coexpression Atlas gudmap_developingGonad_e12.5_epididymis_k2_200 DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.63E-03 1.00E+00 2.50E-02 2.27E-01 18 61 "PNMA8B,PKP4,BACH1,CHM,RBM39,ZC3H11A,EDNRA,EIF4G1,EPB41L2,SMC2,LPAR4,CHIC1,NASP,TMLHE,TET1,ZC3H13,SSBP2,ADAMTS9" Coexpression Atlas gudmap_developingGonad_P2_epididymis_200_k1 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.63E-03 1.00E+00 2.50E-02 2.27E-01 18 61 "ADCY8,ATP1A2,VSTM2A,RGN,DCLK1,CP,MFAP3L,CHRDL1,EDNRA,GABRB1,GAD1,GLUL,CNDP1,PENK,NALCN,VEPH1,MRAP2,PCDHB9" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_FloorPlate_500 e8.5_NeuroEpith_FloorPlate_top-relative-expression-ranked_500 FaceBase_ST1 7.66E-03 1.00E+00 2.50E-02 2.28E-01 86 408 "ERMN,LRCH2,CA4,CBLN1,CCNT1,INA,SYNGR3,CIART,SOCS6,LHX2,CLU,TPP1,FAM19A5,ARMC8,BAG4,CNRIP1,FEZ2,LRRC3B,FAM169A,YTHDC1,FBXL5,ST8SIA3,LPAR6,PIPOX,F3,REEP2,TUBB4A,FOXO3,NOP56,B4GALNT1,SALL3,GPR162,GLDC,ZNF638,PCSK1N,STMN2,PRDM5,RNF165,KAT7,UBE2QL1,ELOVL5,IGFBPL1,TCEAL6,ICA1,INPP1,KHK,IPO5,LMO1,PACRG,AQP11,TM6SF1,MIA2,MYCN,NKX2-2,NOVA1,PAK3,PAX6,GDAP1L1,HMGCLL1,PMP22,PRKCZ,EPDR1,FEZF2,SLC25A36,RPRD1A,RPE,ARMH4,ADAL,TRAPPC13,SALL1,SCG5,ST3GAL3,PPP4R3A,SNRPN,SOX2,SPATA7,ELOVL4,SYT11,ADAMTS17,TAC3,TBL1X,CCDC173,STXBP4,PPIL6,TBC1D15,PDSS2" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200_k1 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 7.72E-03 1.00E+00 2.52E-02 2.30E-01 12 35 "ADCY5,ATP1A2,CACNA2D1,CPEB2,MRVI1,PRKCB,PTHLH,SCN7A,RIMS1,SYNPO2,RGS7BP,MSRB3" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial_Subtype_endothelial cells D_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 7.78E-03 1.00E+00 2.54E-02 2.32E-01 49 213 "ADGRF5,SPARCL1,SEMA6A,PRX,LDB2,SCARB1,CD38,CNN3,ABCG1,PPP1R16B,EDIL3,EDNRB,KLHL5,CALCRL,FLT1,PCDH17,LYVE1,STMN2,ICA1,KIT,STMN1,LMO2,MEST,KITLG,AFDN,CD200,PDE4B,PLTP,SNRK,PTPRB,C1orf54,RGS12,TMEM100,SCN7A,SGK1,BTBD3,SCN3B,SOX11,SPTAN1,THSD1,ST5,TCF4,ZEB1,DOCK9,TEK,TIE1,TJP1,LRRC8A,TUBA1A" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_100 DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 7.79E-03 1.00E+00 2.54E-02 2.32E-01 9 23 "LDLRAD4,ETV1,MEGF10,GABRA4,GABRB1,IFI16,NAP1L2,PCDH8,NPAS3" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k3_200 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 7.95E-03 1.00E+00 2.59E-02 2.36E-01 11 31 "PPP4R4,CALB1,PLXNA4,GABRA4,MATN2,PDE1A,SERPINI1,PCDH18,LGR4,ADGRL3,ZFPM2" Coexpression Atlas gudmap_kidney_adult_RenalCapsule_k2_1000 kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 7.95E-03 1.00E+00 2.59E-02 2.36E-01 79 371 "MTUS1,SRPX,LTBP4,AMPD3,PPFIA2,SHTN1,TMEM108,DOCK11,BCHE,C1QC,RAB29,MYRF,CACNA1A,MS4A7,LY86,ABI3BP,CSF1R,PLXNA4,CYBB,BOC,CHRDL1,CDON,ELN,DENND4A,F3,ABCA8,PTK2B,EFEMP1,FCGRT,FYB1,GALNT15,GCNT2,RAB30,LILRB4,GPM6A,GRIA4,GSN,IRAK3,NCKAP1L,SCRG1,IGF1,ITIH2,KCND3,KCNMA1,LAMA2,VWA5A,MATN2,MEIS1,NBL1,NFIX,NPR2,DDR2,NUCB2,PCDH9,PDGFRA,CDK14,PMP22,PRRX1,NKAIN4,PTPN13,PTPRZ1,RNASEL,CNTNAP3,SCN2A,MRAS,CNKSR2,SLCO1A2,SYNE2,COBL,CYB561A3,TF,ZFPM2,THBS4,SLC44A1,FLRT2,KCNT2,KCNAB1,PLD4,SSPN" Coexpression Atlas GSM854271_500 "Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2" "Immgen.org, GSE15907" 7.97E-03 1.00E+00 2.59E-02 2.36E-01 87 414 "FMNL2,TMCC3,PTCHD1,ALCAM,FGD2,GAS7,APP,SHTN1,ADAM23,NRP2,DST,C1QC,CD86,CD81,MS4A7,B4GALT6,ARHGAP22,LY86,CREB5,GDA,CSF1R,CSF2RA,CST3,SDC3,CTNND1,CX3CR1,CYBB,DOCK4,MYADM,DAPK1,SIRPA,ZEB2,RCAN1,RASA4,EPS8,DENND4A,IGSF6,TLR7,SIRPB1,FCGR1A,FCGR3A,FGR,ZMYND15,TPPP3,GATM,HPGDS,IGF1,LRRC25,DOCK7,ITGAM,LIFR,VWA5A,MITF,MSR1,MYO5A,P2RY13,NCF2,NFE2L2,OPHN1,CDK14,PLTP,PMP22,PILRA,RASGEF1B,PTAFR,RAB3IL1,PID1,ACER3,CCDC88A,SLC11A1,ITPRID2,RGL1,SULF2,FGD4,PSD3,TF,TLR4,TNS1,TPD52,TRPS1,CADM1,LAT2,SLC13A3,AGMO,PMEPA1,PLD4,NLRP3" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_500 dev gonad_e11.5_M_ReproVasc_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 7.97E-03 1.00E+00 2.59E-02 2.36E-01 87 414 "HECW2,ADGRF5,DDX3Y,NRP2,ARHGEF7,C1QC,CA8,LDB2,CD38,ABCG2,LY86,CNN3,ZNF521,CRMP1,HAPLN1,CSF1R,CX3CR1,RASSF2,PITPNC1,ELMO1,FAM107B,CCDC3,EBF1,EDN1,EDNRB,YAF2,LPAR6,CALCRL,PLEKHO1,RASGRP2,DENND4A,CORO2B,FLT1,TMEM107,UFM1,PDLIM5,FYB1,GAP43,PCDH17,GGTA1P,LYVE1,HPGDS,LILRB4,LPAR4,RAPGEF4,STMN2,MAP4K5,NCKAP1L,ZDHHC15,ICA1,IGF1,KIT,LMO2,TM6SF1,MEF2C,MEST,KITLG,MSR1,OPHN1,PDE2A,SPATA6,PROX1,SNRK,MDGA2,PTPRB,TMEM255A,C1orf54,SEMA6D,SGK1,MAGI3,PREX2,BTBD3,LIMCH1,PEG10,THSD1,KLHL4,TEK,C18orf54,TIE1,TJP1,TLR4,TRPC3,TTPA,FLRT2,WIPF1,ZNF711,NAV3" Coexpression Atlas GSM538262_500 "Myeloid Cells, DC.8-4-11b+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-1" "Immgen.org, GSE15907" 7.97E-03 1.00E+00 2.59E-02 2.36E-01 87 414 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,SEMA7A,APP,SHTN1,CASK,ZBTB10,N4BP2L1,ATP6V0A1,MYOM1,ADAM23,NRP2,CFLAR,LARGE1,UBE2L6,B4GALT6,ARHGAP22,CLU,LY86,SLC4A8,CSF1R,OSBPL3,ATRNL1,CST3,SDC3,CYBB,MYADM,RASSF2,SIRPA,GUCD1,RABGAP1L,DSCAM,ARRDC4,PLXNC1,RASA4,IGSF6,EXTL1,SIRPB1,ZMYND15,NEK6,MTHFD2,RAB30,LOXL3,ADAP1,SLC2A6,GYG1,HSF2,DOCK7,JAK2,KIT,VWA5A,ASPRV1,CD200,PFKFB3,CDK14,SSH1,SLC22A23,PTAFR,ROGDI,RGS12,LRRK2,RTN1,SEMA6D,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,C3orf70,TMEM150C,ARC,ATP11A,TCF7,SLC44A1,DDHD1,TNFRSF1B,TRPS1,FNDC5,ZBTB38,SPIRE1,SIGLEC10,PLD4,CERS6" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_100 kidney_P3_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 7.97E-03 1.00E+00 2.59E-02 2.36E-01 24 89 "VAT1L,CRYM,SNCAIP,VCAN,GSDME,SNAP91,EYA1,ST3GAL6,FGFR1,IGSF5,CECR2,FAM107A,HAS2,NCAM1,NPY,CNTN3,PENK,MDGA2,TMEM100,SALL1,CUX2,HEY2,CADM1,LAMP5" Coexpression Atlas gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_200 dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 8.00E-03 1.00E+00 2.60E-02 2.37E-01 10 27 "RUNX1T1,CBLN1,EYA1,PLTP,FAT3,PTCH1,TMEM255A,HHIP,VSNL1,STOX2" Coexpression Atlas gudmap_developingKidney_e15.5_cortic collect duct_100_k3 DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.00E-03 1.00E+00 2.60E-02 2.37E-01 10 27 "AQP4,RGN,FAM149A,SLC35F1,MFAP3L,TENM1,GFRA1,KCNC2,SCN8A,UGT8" Coexpression Atlas GSM476684_500 "gamma delta T cells, Tgd.vg2-.Sp, TCRd+ Vg2- CD44-, Spleen, avg-3" "Immgen.org, GSE15907" 8.10E-03 1.00E+00 2.63E-02 2.40E-01 81 382 "ACTN1,ARID1A,ADD3,AXIN2,ADORA2A,ESYT2,USP28,DGKZ,BAIAP3,HIP1R,ARHGEF1,CHN2,IPCEF1,HDAC9,RIPOR2,HDAC4,TOX,SPOCK2,PITPNC1,DNAJC6,KBTBD11,RASGRP1,RASGRP2,FGF13,MEX3B,AGAP2,EVL,NSG2,FYN,TRAF3IP2,B4GALNT1,RAPGEF6,RAPGEF4,PADI2,BACH2,ZDHHC15,AGFG1,IL6ST,ITPKB,JAK1,KIT,KLRC2,HECTD2,SESN3,ZNF827,PDE2A,PDE3B,PDE4D,ZDHHC8,ABCB1,PIK3CD,JAKMIP1,PLEC,SLC25A23,PACSIN1,SH3KBP1,PRKCZ,SYTL2,SIDT1,SNRK,PRR5L,SATB1,SELL,RASA3,FAM102A,ST8SIA1,DZIP1,SLC12A2,SLC14A1,TET1,TNIK,KIF21B,SYT11,TCF7,AKNA,ARHGAP9,TRIO,RUNDC3B,PMEPA1,ADAMTS10,SPATA13" Coexpression Atlas GSM854255_500 "Myeloid Cells, DC.103-11b+.LuLN, MHCII+ CD11c+ CD8- CD11b+ CD103-, Lymph Node, avg-3" "Immgen.org, GSE15907" 8.14E-03 1.00E+00 2.64E-02 2.41E-01 78 366 "CPNE2,FMNL2,ADCY6,TMCC3,ADORA2A,PTCHD1,ALCAM,SEMA7A,APP,SHTN1,CASK,ZBTB10,ATP6V0A1,ADAM23,NRP2,CFLAR,C1QC,CD86,CDH2,UBE2L6,ARHGAP22,CLU,LY86,SLC4A8,GDA,CSF1R,ATRNL1,CST3,SDC3,CYBB,MYADM,SIRPA,RABGAP1L,DSCAM,ARRDC4,PLXNC1,RASA4,ENO2,IGSF6,SIRPB1,ZMYND15,NEK6,RAB30,LOXL3,ADAP1,SLC2A6,DOCK7,INSM1,TUBB2B,ITGAM,VWA5A,ASPRV1,PFKFB3,CDK14,PLCL1,PLTP,PILRA,SLC22A23,PTAFR,PID1,ROGDI,PRR5L,SEMA6D,SCN4B,ST8SIA1,ARHGEF40,CCDC88A,SAMSN1,SULF2,TMEM150C,ARC,SLC44A1,DDHD1,TNFRSF1B,TRPS1,SPIRE1,PLD4,CERS6" Coexpression Atlas ratio_DE_vs_SC_1000_K2 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#2 PCBC 8.18E-03 1.00E+00 2.65E-02 2.42E-01 107 523 "KCNH8,ACHE,SORCS1,ERMN,NR0B1,BCAR3,ARHGAP20,PCDH10,TRMT9B,APOC1,LGR5,SLC7A14,ARSE,ZBTB10,FGF17,CASTOR3,C5,BAIAP3,CALB1,THSD7A,CCKBR,CDH2,CDH10,COL9A2,CRHBP,TENM4,CSF3R,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,PLCXD3,ARHGAP24,C8orf34,ELMO1,SPOCK3,DSCAM,FAM135B,ERBB4,C1orf61,RASL10A,CAMKK2,TBR1,GAD1,GATM,FREM1,PCDH17,GNAL,GPM6A,GPR37,GSTT2,FAM222A,HAS2,HNMT,CDH20,KCNF1,CLVS2,KIT,MATN3,LRP1B,MOBP,RTL5,MYT1,NODAL,ODF2,SERPINE2,JAKMIP1,PDZRN4,PACSIN1,PPP2R2C,RASGEF1B,MAPK10,ELOVL2,RIPOR1,SLC25A48,ACSS3,FAM184A,PRIMA1,RXRG,MAGI3,ANKRD6,SOX5,SOX10,PEG10,MCF2L2,NFASC,EPB41L3,SULF2,TMEM150C,LEFTY2,RIMBP2,PIK3R5,SEZ6L,TRO,TRPM2,TUBB2A,CADM1,RPRM,PDIA2,VLDLR,KCNK12,PCDH20,PLPP4,ANKS1B,MEIS3,FAM13C,CASC15" Coexpression Atlas gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k5 DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.25E-03 1.00E+00 2.67E-02 2.43E-01 4 6 "RUNX1T1,EFEMP1,PCDH8,PRRX1" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_1000_k3 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.27E-03 1.00E+00 2.68E-02 2.44E-01 31 123 "EMILIN3,TAOK1,ARHGAP20,LTBP4,PTCH2,DDX3Y,COL9A2,PUM1,ZEB2,EDNRA,ELN,LRRC17,CSDC2,IGF1,VWA5A,MEF2C,MMP16,NFIA,NFIX,PDGFRA,FXYD1,MEG3,ARX,ZCCHC24,OBSL1,HHIP,TNS1,NR2C2,UBTF,FLRT1,PMEPA1" Coexpression Atlas GSM476681_500 "gamma delta T cells, Tgd.vg2-.act.Sp, TCRd+ Vg2- CD44+, Spleen, avg-3" "Immgen.org, GSE15907" 8.30E-03 1.00E+00 2.68E-02 2.45E-01 80 377 "AXIN2,GRAMD1B,ADORA2A,ESYT2,PITPNM2,PKP4,BMP7,BAIAP3,HIP1R,ARHGEF1,CHN2,ABI3BP,CSF1R,OSBPL3,IPCEF1,RIPOR2,HDAC4,TOX,SPOCK2,PITPNC1,RABGAP1L,KBTBD11,FAM78B,RASGRP1,TNK2,DENND4A,ST3GAL6,FGF13,CAP2,AGAP2,NSG2,ST6GALNAC3,ZNF512,FYN,TRAF3IP2,B4GALNT1,RAPGEF6,ATP8A2,BACH2,ZDHHC15,AGFG1,ITPKB,JAK1,KCNK1,KIT,KLRC2,KLRC3,ZNF827,PDE2A,PDE3B,ABCB1,POU6F1,PPP3CC,PRKCZ,SYTL2,SIDT1,RGS3,PRR5L,SATB1,IL17RB,PEAR1,SELL,FAM102A,DZIP1,SLC12A2,SLC14A1,TET1,TNIK,KIF21B,SULF2,ACSBG1,SYT11,KLHL4,TCF7,GPRIN3,TRIO,RUNDC3B,CLDND1,ZBTB16,SPATA13" Coexpression Atlas gudmap_developingGonad_e18.5_testes_500_k5 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.36E-03 1.00E+00 2.70E-02 2.46E-01 32 128 "AGT,SORCS2,AMH,ARHGDIG,ST3GAL5,DDR1,CBLN1,ADGRG1,CLU,FADS2,NIPBL,RCAN1,DTNA,EDNRA,MBNL2,EPB41L2,GPM6B,GPR37,JAK1,MEF2C,MT3,PAK3,PDGFRA,SEMA5B,MEG3,ARX,SULF2,ACSBG1,OBSL1,HHIP,TNS1,TST" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_1000_k1 DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.40E-03 1.00E+00 2.71E-02 2.47E-01 50 219 "USP31,ADGRF5,ARRB1,C1QC,LDLRAD4,CA8,LDB2,CD86,CD38,MS4A7,LY86,CSF1R,CX3CR1,CYBB,SIRPA,ELMO1,CCDC3,DNM2,EDNRB,EPHB1,IGSF6,TLR7,SIRPB1,F8,FCGR1A,FYB1,GGTA1P,LYVE1,NCKAP1L,IRF8,PIK3AP1,TM6SF1,MSR1,P2RY13,NCF2,P2RX7,PTPRB,SGK1,SLA,SLC11A1,ARHGAP26,SAMSN1,TAL1,ARHGAP9,TEK,TLR4,NPL,TRPC3,WIPF1,FAM13C" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_1000 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 8.48E-03 1.00E+00 2.74E-02 2.49E-01 34 138 "KDM5D,AMH,SEMA7A,DDX3Y,JAM2,CLU,FADS2,MAGED1,CD99L2,MRO,PLXNC1,EPS8,ERBB4,FAM198B,PTK2B,TUBB3,FGF13,IQGAP2,GATM,PPARGC1A,ADGRA3,GPM6B,STON1,LRRTM3,PAK3,SERPINE2,RASGEF1B,MASP1,TSPYL2,SYNE2,THRA,CLDND1,ADAMTS9,WNK3" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500_k2 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 8.53E-03 1.00E+00 2.75E-02 2.50E-01 36 148 "ADORA1,PCDH19,DOC2A,CAMK2B,SLC32A1,TENM4,GREB1,USP3,HEYL,EPHB1,ST3GAL6,FKTN,FGFR1,PSD2,TRIM16,IGSF5,BRD8,GLDC,ADGRA3,DIDO1,PRDM5,HES5,CLEC18A,MARK1,TM6SF1,NPY,OXTR,PRTG,PDE1C,DUSP15,EMID1,SALL1,SH3BGR,SYT11,HEY1,URM1" Coexpression Atlas JC_iEC_1000_K4 JC_iEC_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 8.53E-03 1.00E+00 2.75E-02 2.50E-01 36 148 "ADCY2,GALNT13,TMEM108,HAP1,SYT6,DLGAP1,AKAP5,HS3ST5,CRYBB1,AIF1L,SEZ6,CDHR1,PIPOX,IGSF5,PCDH11X,GNG4,LINGO1,MIER3,LRRTM3,CHST6,ZDHHC22,SALL1,SCN8A,PREX2,SOX2,RHBDL3,SYT1,PCDHA6,IL34,UGT8,MGAT5B,VGF,VSNL1,KCNK12,LYPD6,PCDH15" Coexpression Atlas gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_500 dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.53E-03 1.00E+00 2.75E-02 2.50E-01 36 148 "FMNL2,LGR5,PPP4R4,ATP2B3,CACNB2,MAGI1,CHRM4,PLXNA4,DOCK4,DAPK1,RASGRP1,KLHL5,EMX2,NRN1,GABRA4,GABRB1,GALC,IGF1,KLHL23,KITLG,MYO9A,PPP3CC,GDPD1,SEMA6D,TNFRSF19,STUM,RASA3,SLC4A3,KDM3A,ST5,ACTR6,TNNT1,FNDC5,ELFN1,LYPD6,FRMD6" Coexpression Atlas gudmap_developingKidney_e11.5_ureteric bud_1000_k1 DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.70E-03 1.00E+00 2.80E-02 2.55E-01 58 261 "SEMA6A,CEP126,CDC14B,ZNF599,OSGIN2,HAPLN1,KATNAL2,SMG7,CHRDL1,RAB39B,EEF1D,SPECC1,USP21,PRELID3A,FAM184B,GAP43,MTHFD2,KIRREL3,GRIK4,FAM19A2,RABL2A,KIF5C,KIT,RSPO2,CNTN3,PRTG,PFKFB3,PKM,KCTD15,HMGCLL1,CEP97,CCDC40,FAM184A,GAL3ST4,NUDT11,C12orf49,SCN3A,SHMT2,ST6GAL1,KBTBD4,SPHKAP,KIF21B,SOX11,CAND2,SYT11,CUX2,AKNA,MEAF6,SF1,FMN2,ZNF142,ZNF184,LRP8,NAV2,FZD3,CAMK1G,VANGL2,AAAS" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_500 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 8.71E-03 1.00E+00 2.80E-02 2.55E-01 62 282 "HECW2,ADGRF5,SPARCL1,SEMA6A,APBB2,SHROOM2,DOCK11,NRP2,C1QC,LDB2,FMNL3,CD38,MS4A7,ABCG2,LY86,ARHGEF6,ZNF521,HAPLN1,CSF1R,CX3CR1,CYBB,ELMO1,EBF1,EDNRB,CALCRL,RASGRP2,DLC1,FLT1,PDLIM5,FYB1,GAP43,PCDH17,GGTA1P,HPGDS,LILRB4,LPAR4,RAPGEF4,MAP4K5,NCKAP1L,ICA1,LMO2,TM6SF1,MEF2C,PDE2A,SNRK,MDGA2,PTPRB,TMEM255A,C1orf54,SEMA6D,PREX2,LIMCH1,PEG10,THSD1,KLHL4,TEK,TIE1,TJP1,RFTN2,NAV3,FAM13C,DOCK8" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K4 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 FaceBase_RNAseq 8.75E-03 1.00E+00 2.81E-02 2.56E-01 53 235 "DGCR6,ACTN2,OSBPL1A,TBC1D14,GAS7,APOC2,CPNE5,ARRB2,TTLL9,ZNF599,CA12,ARHGEF1,SUMF2,CREM,CRY2,CRYM,ELN,NCALD,CDKL3,EFEMP1,ST3GAL6,PPP1R1B,HPCAL4,ZMYND15,APOPT1,TPK1,FYB1,RAPGEF4,LIX1,GPR155,MID1,BCO1,NTRK3,ETFRF1,ENPP2,PILRA,CYBC1,DEF8,STRC,KCNIP3,SEMA6D,SH3BP2,NAXD,TSPYL2,C11orf87,PDLIM2,IQCE,LEFTY2,TMOD1,LRTM2,KLC2,LAMP5,PMEPA1" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_1000_k4 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 8.75E-03 1.00E+00 2.81E-02 2.56E-01 27 104 "SERPINA3,SPARCL1,PI16,ENTPD2,ABI3BP,MFSD4A,DMPK,CPEB2,ABCC9,SORBS1,ILDR2,TPPP,GSN,NFIX,HCN1,PFKP,PRKAB2,PTHLH,SMTN,RIMS1,SNAP25,TACC1,TNS1,TPM1,SYNPO2,ZBTB16,RGS7BP" Coexpression Atlas gudmap_developingKidney_e11.5_metaneph mesench_100 DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 8.87E-03 1.00E+00 2.85E-02 2.60E-01 23 85 "CDH2,COL9A1,CRMP1,CRYM,SPOCK2,SNAP91,ELAVL4,KCNMB2,EYA1,SPSB4,CHL1,GALC,FAM19A2,FAM107A,HAS2,PCDH8,PRTG,GAL3ST4,SALL1,MAPK12,CSRNP3,ANKRD6,LRP8" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_1000_k5 DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.04E-03 1.00E+00 2.90E-02 2.64E-01 51 225 "TTYH1,CSMD3,ADORA1,BEND6,SEMA7A,GAS7,AQP4,ZFYVE28,DDX3Y,ADAM23,MMD2,CA4,VXN,CBLN1,SCARB1,JAM2,ENO2,KCNMB2,SYNCRIP,CAMKK2,CGREF1,DKK3,PCDH11X,MAEL,HSD17B1,IFI16,ITPKA,METTL21A,KCNC2,CHIC1,TM6SF1,MYO7A,NFIA,ENPP2,NKAIN4,RASGRF1,RGS4,SOX8,ARX,EFHD1,SORCS3,ZHX3,SPP1,DDN,C11orf87,ADHFE1,HHIP,RICTOR,SLC13A3,LYPD6,CBLN2" Coexpression Atlas gudmap_kidney_P1_CapMes_Crym_100 kidney_P1_CapMes_Crym_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 9.13E-03 1.00E+00 2.93E-02 2.67E-01 18 62 "AMPH,IL33,CACNA2D1,CRYM,SNCAIP,VCAN,SPOCK2,SNAP91,EYA1,IGSF5,GFRA1,HAS2,PENK,FAT3,MDGA2,ROBO2,TMEM100,SALL1" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_1000 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 9.13E-03 1.00E+00 2.93E-02 2.67E-01 18 62 "ADGRF5,SPARCL1,SEMA6A,LDB2,ZNF521,HAPLN1,PLEKHO1,GAP43,LIFR,TMEM255A,SEMA6D,PEG10,RGL1,ARHGEF9,KLHL4,HEY1,FLRT2,ZNF711" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Overall_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Overall_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 9.22E-03 1.00E+00 2.95E-02 2.69E-01 42 179 "NDRG2,SPARCL1,LTBP4,RUNX1T1,CD81,CDO1,SLIT2,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,FHL1,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,PBX1,PDGFRA,SERPINE2,FXYD1,PMP22,SEPT4,NKAIN4,PTCH1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,TGFBR3,HHIP" Coexpression Atlas gudmap_kidney_adult_Podocyte_MafB_200 kidney_adult_Podocyte_MafB_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 9.22E-03 1.00E+00 2.95E-02 2.69E-01 42 179 "C1QTNF1,EPB41L5,UPRT,TMEM108,B3GALT2,CA12,THSD7A,MYOM2,DOCK4,ARHGAP24,AIF1L,MAGI2,TMTC1,OPTN,TLR7,ACSL4,ST3GAL6,SGIP1,ST6GALNAC3,GABRA4,GABRB1,ILDR2,GALC,IQGAP2,MALT1,PARD3B,SYNPO,ITGAV,MYO6,PTH1R,PTPRO,RIPOR1,RAVER2,ROBO2,FAM81A,CPEB4,KANK1,TMEM150C,FRYL,DAAM2,PLEKHH2,CERS6" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k5 DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.23E-03 1.00E+00 2.95E-02 2.69E-01 30 119 "USP31,CACNA1B,MAP7,CTNND2,CALN1,EDN1,FEM1B,SEMA3D,F3,TRIM16,DACH2,GFRA1,SOX21,FRMD5,ASPRV1,VWA2,OXTR,DIRAS2,RBBP8,ARMH4,SATB1,SOX6,SLC15A2,SOX2,ARC,HIF3A,TIAM1,SLAIN1,SF1,PHTF2" Coexpression Atlas gudmap_developingKidney_e15.5_Endothelial cells_500 DevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.24E-03 1.00E+00 2.96E-02 2.69E-01 81 384 "USP31,ADRB2,HECW2,ADGRF5,NRP2,GPR146,C1QC,LDLRAD4,CA8,LDB2,CD86,CD38,MAP4K4,LY86,RBM39,CRMP1,HAPLN1,CSF1R,PPP1R16B,CX3CR1,CYBB,ELMO1,CCDC3,ABCC9,SEZ6L2,EDNRB,EPHB1,IGSF6,F8,DLC1,FCGR1A,FLT1,FYB1,FAM184B,GATM,PCDH17,GGTA1P,LYVE1,NCKAP1L,ICA1,IRF8,IFI16,LMO2,PIK3AP1,TM6SF1,MEF2C,MEIS2,CD200,MSR1,MYO7A,P2RY13,NCF2,PDE2A,RELN,PTPRB,TMEM255A,PRR5L,MAPK12,SGK1,ST8SIA1,SLA,PREX2,SAMSN1,THSD1,TAL1,KLHL4,ARHGAP9,TEK,TF,TIE1,TLR4,ERCC6L2,NPL,TRPC3,VAV1,WIPF1,PLD4,RGS7BP,FAM13C,DOCK8,MSRB3" Coexpression Atlas facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4 facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K4 Gudmap RNAseq 9.31E-03 1.00E+00 2.98E-02 2.71E-01 49 215 "C1QTNF1,PDE8B,MYOM1,CALB1,DLGAP1,ARHGEF6,DGKB,ZNF804A,ABCC9,EBF1,EMX2,LRRC17,EPHB1,TLR7,FCGRT,TPPP3,LOXL3,NR3C1,GRM7,GUCY1A1,IL6ST,IL11RA,MITF,CCDC80,NTRK2,PDE1A,PDE3A,PDGFRA,PIK3R1,PLCL1,FXYD1,PTN,PYGM,FAM184A,DOCK10,PREX2,SLC8A1,ZCCHC24,NKAIN2,RGL1,TNS2,GALNT17,TLR4,DAAM2,TMEFF2,PLSCR4,FAM13C,MSRB3,SSPN" Coexpression Atlas gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k4_500 dev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.40E-03 1.00E+00 3.00E-02 2.74E-01 21 76 "DDX3Y,NRP2,C1QC,HAPLN1,CSF1R,CX3CR1,FAM107B,CCDC3,EDN1,EDNRB,FYB1,LYVE1,HPGDS,NCKAP1L,MSR1,PROX1,SGK1,KLHL4,C18orf54,TLR4,TRPC3" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k2 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.41E-03 1.00E+00 3.00E-02 2.74E-01 32 129 "EMILIN3,ADD3,LRCH2,NRP2,SGCE,CDH2,SLIT2,AKAP5,CRHBP,AK5,EPHB1,FLT1,PNMA2,GABRA3,PCDH11X,GPR37,RAPGEF4,GRIN2C,MYO6,PDE1A,PCDH18,PMP22,ELMOD1,DOCK10,SPHKAP,C11orf87,NEK4,ANO4,ZFPM2,THBS4,RBFOX2,PLPPR5" Coexpression Atlas ratio_DE_vs_SC_1000_K5 ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 9.43E-03 1.00E+00 3.01E-02 2.74E-01 110 542 "KCNH8,ACHE,SORCS1,ERMN,NR0B1,BCAR3,PCDH10,TRMT9B,APOC1,LGR5,SLC7A14,ARRB1,ARSE,ZBTB10,FGF17,CASTOR3,C5,BAIAP3,CALB1,CCKBR,CDH2,CDH10,LGI1,COL9A2,CRHBP,TENM4,CSF3R,IPCEF1,CNTNAP2,PLXNA4,PPP1R16B,ARHGAP24,C8orf34,ELMO1,LYPD1,SPOCK3,DSCAM,FAM135B,ERBB4,C1orf61,RASL10A,CAMKK2,TBR1,GAD1,GATM,FREM1,PCDH17,GNAL,GPM6A,GPR37,GSTT2,FAM222A,HAS2,CDH20,KCNF1,CLVS2,KIT,MATN3,LRP1B,MOBP,RTL5,MYT1,NODAL,ODF2,PAX6,SERPINE2,JAKMIP1,PDZRN4,PACSIN1,PPP2R2C,RASGEF1B,MAPK10,ELOVL2,RIPOR1,SLC25A48,ACSS3,FAM184A,PRIMA1,ZFHX4,WLS,RXRG,MAGI3,ANKRD6,SOX5,SOX10,PEG10,MCF2L2,NFASC,EPB41L3,SULF2,TMEM150C,LEFTY2,RIMBP2,PIK3R5,SEZ6L,TRH,TRO,TRPM2,TUBB2A,CADM1,RPRM,PDIA2,VLDLR,KCNK12,PCDH20,PLPP4,ANKS1B,MEIS3,FAM13C,CASC15" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_1000_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.45E-03 1.00E+00 3.01E-02 2.74E-01 48 210 "TAOK1,LCORL,MADD,DDX3Y,ZNF583,CDC42,AKAP5,DZIP3,APPL1,HDAC9,TMEM130,SACS,CPEB2,CD320,SCML2,PDLIM5,PHYHIPL,GABRA4,TDRKH,GPR19,TPPP,KCND2,HECTD2,KITLG,GPR137C,C19orf57,PPP3CC,ANKHD1,EML5,ATP8B4,ACER3,FNIP1,HSPA4L,WDR47,CPEB4,ZNF667,SP4,ARHGAP26,LARP4,VPS13A,SYN2,SIRT1,RUNDC3B,UGT8,VSNL1,LYPD6,PHTF2,RSPRY1" Coexpression Atlas gudmap_developingKidney_e15.5_Peripheral blastema_1000_k1 DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 9.45E-03 1.00E+00 3.01E-02 2.74E-01 48 210 "RNF157,SORCS1,PCDH19,SEMA6A,ANK3,EPB41L5,CASK,OSGIN2,CH25H,CDH2,NIPBL,NSL1,PYGO1,MTX3,EFNA3,ATP8A1,SLC9B2,PRELID3A,CHL1,KIRREL3,BRD8,PRDM5,HAS2,ARHGAP19,LIG4,MID1,PCDH8,GPR85,ANLN,CEP41,GAL3ST4,CRTAC1,FIGN,SEC61A2,PRR5L,HUNK,SALL1,SFPQ,ANKRD6,SLC1A3,SLC9A5,CEP68,CADM1,CCDC14,XPO1,ZNF24,PHTF2,NETO2" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonMes_Sma_k3_500 dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 9.51E-03 1.00E+00 3.03E-02 2.76E-01 36 149 "TMEM108,MYRF,CALB1,CDH10,CDH18,CNTFR,AKAP5,CLIP3,TENM4,ATRNL1,DNM1,C8orf37,F3,TUBB4A,FLNC,BVES,GUCY1A2,TCEAL6,KCND2,MAP2,MATN2,MEIS1,CCDC80,NEFM,NME4,PCDH18,PRRX1,PTN,RADX,KCNIP1,PKNOX2,PALLD,ZFPM2,ASXL3,TRPS1,PLEKHH2" Coexpression Atlas JC_iEC_500 JC_iEC_top-relative-expression-ranked_500 PCBC 9.57E-03 1.00E+00 3.05E-02 2.78E-01 101 493 "ASIC2,GALNT13,KIAA1211,PCDH19,BBOX1,AMH,TMEM108,AZGP1,CACNA1E,CALB1,HAP1,SYT6,CH25H,DGKI,LONRF2,CDH10,LGI1,DLGAP1,NOG,SYNPR,TMEM155,AKAP5,HS3ST5,RIPOR2,AIF1L,DCC,C8orf34,MFAP3L,GRIN3A,DPP6,MAMLD1,TENM1,CALCRL,EN2,PIPOX,HSPA12B,FOXG1,PNMA2,NRG3,GAP43,DNER,GBX2,PCDH11X,MCHR1,STMN2,BVES,LINGO1,ARHGAP36,LRRTM3,KCND3,PIK3AP1,MSR1,NCAM1,NDP,NELL1,NRCAM,NTRK2,OXTR,SNTG1,PCSK1,PCSK5,SLC10A4,PMP22,TRHDE,FA2H,PTHLH,PTPRB,RNASE1,RPE65,TMEM100,EMID1,SOX8,SALL1,SELL,STUM,SGK1,PREX2,LIMS2,OGDHL,SOX2,SPP1,THSD1,ARC,SYT1,POPDC3,KLHL4,ANO4,TBX15,VWC2,PCDHGB6,TEK,TIE1,ASXL3,TLL2,TRH,UGT8,VGF,EML6,LAMP5,SLC30A3,PCDH15" Coexpression Atlas Lungmap Mouse Lung PND3 MatrixFB Subtype MyoFB-A(1) Lungmap Mouse Lung PND3 MatrixFB Subtype MyoFB-A(1) Lungmap CCHMC 9.61E-03 1.00E+00 3.06E-02 2.79E-01 57 257 "KIDINS220,C1QTNF3,LTBP4,ATP2A2,DDR1,CD81,CLU,CNN3,ARHGEF6,CNTFR,MAGED1,VCAN,SOCS5,ZEB2,E2F5,EDNRB,TUBA1B,TMEM151A,DKK3,BRD8,STARD3,FERMT2,GPM6A,FUT10,TUBA1C,STMN2,WIF1,BACH2,DHX35,CD200,NFIA,NFIX,PDE3A,PFKP,FXYD1,PRRX1,PTN,PTPRZ1,FAM184A,FIGN,RIC8B,PBRM1,SEC14L1,NAPB,PDZRN3,CAMTA2,WWC1,TCF4,PCDHGA9,CRTC1,TEK,GZF1,TIMP4,TPM1,TPM4,UCHL1,TUBA1A" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_500_J DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.62E-03 1.00E+00 3.06E-02 2.79E-01 82 390 "SERPINA3,NDRG2,ANK1,APC,MYOM1,NRP2,DST,CACNA2D1,CAMK2D,MYOM2,CHGB,ABI3BP,MFSD4A,GDA,CNTNAP2,DNAJC6,MFAP3L,SPOCK3,RABGAP1L,DMPK,CPEB2,ABCC9,HIPK3,ELN,MRVI1,NRN1,TUBB3,FHL1,SORBS1,DKK3,GALNT15,DNER,IGSF5,LYVE1,PRUNE2,STMN2,TPPP,GSN,IFI16,IL6ST,KCNMA1,KIF5C,MAP4,MBP,MYH3,MYH7,NEFM,NFE2L2,NPTX2,PFKP,PRKCB,MAPK10,PRPH,PTHLH,RET,RYR3,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,SMTN,SLC14A1,RIMS1,SNAP25,DBNDD2,C11orf87,POPDC3,TF,HHIP,TLR4,TNNT1,TNS1,TPM1,TPM2,SYNPO2,PPIL6,RBFOX3,AGMO,ZBTB16,DOCK8,MSRB3" Coexpression Atlas ratio_SC_vs_ECTO_2500_K4 ratio_StemCell_vs_induced-Ectoderm_top-relative-expression-ranked_2500_k-means-cluster#4 PCBC 9.82E-03 1.00E+00 3.12E-02 2.84E-01 70 326 "EMILIN3,FAM43B,KLHL32,ADCY5,CCDC85A,C1QTNF1,SPARCL1,ATP1A3,AZGP1,GPR146,LDHD,IL33,DIRAS1,CH25H,RUNX1T1,ARHGEF25,EVI5L,ACBD5,CRYM,PLXNA4,BOC,MYADM,GRIN3A,FAM78B,KRBA2,EDNRB,EEF1A2,DUSP27,HSPA12B,TMEM132C,SORBS1,GALNT15,IP6K3,ALDH1L1,GNAO1,DIPK1C,RAPGEF4,GRIK2,COQ10A,NEGR1,IDH3A,MYLK2,LRRC25,KIAA1755,ITGAM,KCNK1,TTYH2,MT1M,MX1,TMEM38A,ST8SIA5,FXYD1,PLTP,VSTM2L,FITM2,DUSP15,SGSM1,LRRK2,HOGA1,SCN4B,SSTR1,POPDC3,TIMP4,RASD2,SYNPO2,VIPR2,TRIM9,SLC30A3,SHD,PPP1R3F" Coexpression Atlas GSM777059_500 "Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4" "Immgen.org, GSE15907" 9.82E-03 1.00E+00 3.12E-02 2.84E-01 91 439 "CPNE2,SERPINA3,FMNL2,ADGRF5,SEMA6A,BCAR3,LTBP4,CDC42BPA,SEMA7A,APP,ASTN1,NRP2,IL33,CA8,LDB2,B4GALT6,SLIT2,CLU,FAM189A2,FADS2,ZNF521,MFSD4A,CP,CDC42BPB,SNCAIP,CSF1,ARHGEF10,MICAL2,PLXNA4,CTNND1,DOCK4,SIRPA,ARMCX4,RCAN1,ARRDC4,ECM2,EDN1,EDNRB,SEMA3D,TMTC1,ELN,CALCRL,F8,ARMCX1,DLC1,FCGRT,ST6GALNAC3,NCKAP1,LYVE1,RND1,FERMT2,GPM6A,GUCY1A1,ICA1,LIFR,MEIS2,MSR1,FXYD6,NFIA,NPR2,CLDN11,PBX1,PDE2A,ENPP2,PLCD1,PMP22,PROX1,RELN,PTPRB,RGS4,ROBO1,PEAR1,SH3GL3,BTBD3,SMTN,UNC5B,RGL1,KLHL4,DOCK9,ARHGEF12,TNS2,TEK,TGFBR3,TIE1,TIMP4,TJP1,NPL,FLRT2,NPDC1,ADAMTS9,MSRB3" Coexpression Atlas ratio_SC_vs_MESO_500_K4 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_500_k-means-cluster#4 PCBC 9.83E-03 1.00E+00 3.12E-02 2.84E-01 19 67 "ATP1A2,ATP1A3,LDHD,CHGB,CABP1,CP,INSYN1,PPM1L,TMOD2,ST8SIA5,FXYD1,SCHIP1,PTPRN2,PYGM,SCN4B,ABCC8,TIMP4,RASD2,LGI4" Coexpression Atlas GSM605886_100 "Myeloid Cells, Mo.6C-IIint.Bl, CD115+ B220- CD43- Ly6C- MHCIIint, Blood, avg-5" "Immgen.org, GSE15907" 9.83E-03 1.00E+00 3.12E-02 2.84E-01 19 67 "ATP1A3,ZFYVE9,GDA,CSF1R,CX3CR1,CYBB,SIRPA,IGSF6,TLR7,SIRPB1,FCGR3A,FGR,ITGAM,LDLRAD3,PILRA,SLC11A1,SLC12A2,FGD4,PLD4" Coexpression Atlas gudmap_developingGonad_P2_epididymis_500_k3 DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 9.88E-03 1.00E+00 3.13E-02 2.85E-01 12 36 "LCORL,CHM,RBM39,GSDME,EMX2,SCML2,GABRA4,ILDR2,DNER,TMLHE,SYNE2,ADAMTS9" Coexpression Atlas GSM476655_500 "gamma delta T cells, Tgd.vg2+24ahi.Th, TCRd+ Vg2+ CD24+, Thymus, avg-3" "Immgen.org, GSE15907" 9.98E-03 1.00E+00 3.16E-02 2.88E-01 88 423 "ADCY6,AXIN2,ALS2,BMP7,LDLRAD4,CAMK2D,PRC1,RCBTB2,FADS2,CSNK1E,PPP1R16B,CX3CR1,TOX,PITPNC1,DNAJC6,KBTBD11,DLG4,RASGRP1,LPAR6,TNK2,CORO2B,CHST15,MEX3B,FOXM1,SLC37A3,SMC2,FYN,ARPP21,ACSS1,TUBA8,GFRA1,DCLK2,TDRKH,TOX2,ARHGAP19,SCIN,INPP5B,KIT,STMN1,LIG4,HECTD2,AQP11,PPM1L,RCOR2,P2RX7,ZNF827,PDE4D,ZDHHC8,ANLN,SLC25A23,SH3KBP1,SYTL2,BEND5,DPF2,RGS12,ATP8B4,IL17RB,SELL,GALNT10,FAM102A,PPM1E,ST6GAL1,ST8SIA1,DZIP1,ANKRD6,TET1,WDTC1,TRERF1,TNIK,SOX5,KIF21B,CAND2,SSTR2,TCF7,TCF12,TMEM121,TIAM1,BHLHB9,TRIO,TTC3,UBE2H,NSD2,PMEPA1,SLC38A1,NAV2,MVB12B,VANGL2,ADAMTS10" Coexpression Atlas gudmap_developingLowerUrinaryTract_P1_bladder_1000_B DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.00E-02 1.00E+00 3.17E-02 2.89E-01 152 776 "SERPINA3,DGCR6,ACTN1,NDRG2,ADCY5,TMCC3,ADD3,SPARCL1,SRPX,LTBP4,ANK1,PI16,DDX3Y,ATP2A2,MYOM1,NRP2,DST,CALM1,CAMK2D,CAMK2G,CAST,CLDN10,ENTPD2,DCLK1,LRRFIP1,CDO1,RAB3C,CNTN1,COL4A5,ABI3BP,MFSD4A,GDA,PDE4DIP,CNTNAP2,MYADM,DBI,MFAP3L,DDX46,SACS,SPOCK3,RABGAP1L,DMPK,CPEB2,DTNA,ABCC9,SH3GLB1,MBNL2,ELN,EPB41L2,MRVI1,F3,FHL1,FLNC,SORBS1,PDLIM5,FUT9,TPPP3,SDCBP2,ILDR2,IGSF5,ADAM28,LYVE1,GNAO1,GP1BB,PRUNE2,GPM6B,MCHR1,STMN2,TPPP,GSN,BVES,AP4S1,SMAP1,IFI16,IL6ST,KCNK1,NEFM,NFE2L2,ALDH1L2,NFIX,NPTX2,HCN1,PDPK1,PFKP,PIK3R1,PLEC,FXYD1,FA2H,PPP2R2B,PRKAB2,PRKCB,SYTL2,PTHLH,PTPRB,PLEKHB2,MEG3,RTN1,RYR3,SATB1,ATXN1,SCN2A,SCN7A,STUM,SH3BGR,FHOD3,PREX2,SMTN,LIMS2,SLC14A1,CPEB4,RCOR3,RIMS1,SNAP25,PALLD,SCN3B,SON,ZCCHC24,FNBP1,DBNDD2,RBM26,C11orf87,ATP10B,NACAD,KANK1,SYPL1,COBL,POPDC3,TACC1,SEMA4A,WWC1,TF,HHIP,ENHO,TNNT1,TNS1,TPM1,TPM2,SYNPO2,PPIL6,UCHL1,RBFOX3,AGMO,ZBTB16,STOX2,RGS7BP,FAM13C,DOCK8,RTN4,ACTR3B,MSRB3,ZDHHC20,SSPN" Coexpression Atlas GSM777050_500 "Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5" "Immgen.org, GSE15907" 1.03E-02 1.00E+00 3.25E-02 2.97E-01 96 467 "SERPINA3,NDRG2,GALNT16,ADCYAP1R1,SPARCL1,SRPX,LTBP4,GPAM,APP,ATP1A2,NRP2,SGCE,IL33,THSD7A,ARHGEF25,ENTPD2,DCLK1,CLU,FADS2,CNTFR,MAGED1,ABI3BP,CP,CLIP3,CSF1,ATRNL1,CTNND1,BOC,ARHGAP24,DAPK1,CHRDL1,ECM2,ABCC9,EBF1,EGFR,PCOLCE2,ELN,F3,EFEMP1,DLC1,FCGRT,FGFR1,AMOTL2,SCARA3,TPPP3,GAA,GABRA3,NCKAP1,GFRA2,FERMT2,GPM6B,STMN2,GRB10,GSN,GSTM5,GUCY1A1,IL11RA,LAMA2,LIFR,MAOB,MATN2,MEIS1,MEST,CCDC80,SCG3,NBL1,NFIA,NFIX,NPR2,DDR2,PDE3A,PDGFRA,ENPP2,PENK,CDK14,FXYD1,PLTP,PMP22,PRRX1,EPDR1,PTPRG,KIRREL1,RTN1,SCN7A,PKNOX2,ST5,TNS2,TF,TGFBR3,CSMD1,SYNPO2,PLEKHH2,NPDC1,AGMO,SEMA3B,MARCH8" Coexpression Atlas gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k2 DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.03E-02 1.00E+00 3.25E-02 2.97E-01 29 115 "ANK3,ATP1A2,KALRN,CDH2,COL9A1,SIPA1L1,PYGO1,SPOCK2,SNAP91,RAB39B,KMT5B,KCNMB2,RCSD1,PRELID3A,DACH2,TVP23A,KIAA1958,FAM19A2,HAS2,MSI1,CEP41,RPS6KA2,MAPK12,DZIP1,ANKRD6,C11orf87,CEP68,LRP8,NETO2" Coexpression Atlas gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k4_1000 dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.03E-02 1.00E+00 3.25E-02 2.97E-01 29 115 "ABAT,SEMA7A,SHTN1,CDC14B,BCHE,RGS11,DST,RGN,CDH2,ADGRG1,CLU,FADS2,GPRASP1,MRO,PLXNC1,CERCAM,AFF2,ZMAT1,GATM,ADGRA3,TTYH2,SYTL4,MOV10,RASGEF1B,TNIK,TSPYL2,FGD4,TST,WNK3" Coexpression Atlas ratio_SC_vs_MESO_1000_K3 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#3 PCBC 1.03E-02 1.00E+00 3.26E-02 2.97E-01 40 170 "ZFYVE28,PLA2G4C,ALDH4A1,LDB2,UBE2L6,ABCG2,ARHGEF6,SNCAIP,PLPPR4,AK5,DOCK2,EBI3,CALCRL,LRRC17,CGREF1,GPR153,ST6GALNAC3,RAPGEF4,DISP2,KCNMA1,CREG2,MAP2,SESN3,STK32C,MX1,LAYN,NOVA2,TMOD2,NALCN,KLK6,PTPRN2,SLC6A15,BAALC,FERMT1,SMOC1,INKA2,SLC37A2,TCF4,SLC35G2,DNAJC12" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_100_k3 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.03E-02 1.00E+00 3.26E-02 2.97E-01 11 32 "PNMA8B,BACH1,RUNX1T1,LPAR4,CHIC1,MEIS2,PCDH9,C1orf54,MEG3,CBX5,SSBP2" Coexpression Atlas ratio_SC_vs_MESO_1000_K4 ratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4 PCBC 1.03E-02 1.00E+00 3.26E-02 2.97E-01 11 32 "GALNT9,TMEM35A,TUBB3,AKAP3,GAP43,NPTX1,NTRK3,PCSK1,RASGRF2,SPP1,LAMP5" Coexpression Atlas GSM854320_500 "Myeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2" "Immgen.org, GSE15907" 1.04E-02 1.00E+00 3.27E-02 2.98E-01 84 402 "MTUS1,ABCD2,AMPD3,PI16,SUGT1P4-STRA6LP-CCDC180,GAS7,APOC2,APP,CASK,ATP1A3,ADAM15,SCARB1,ZFYVE9,LY86,GDA,CSF1R,CSF2RA,CSF3R,ATRNL1,GALNT9,VCAN,CST3,SDC3,CTNND1,CX3CR1,CYBB,MYADM,KIAA0513,DGKG,SIRPA,EPS8,IGSF6,TLR7,SIRPB1,F5,FCGR1A,FCGR3A,OLFM1,FGR,FLT1,CAMKK2,TPPP3,GCNT2,ADAP1,SLC2A6,IRAK3,PADI2,HP,IFI16,LRRC25,IL6R,ITGAM,LAMP2,LIFR,LDLRAD3,MSR1,P2RY13,NCF2,P2RY1,PFKFB4,PLTP,PILRA,PTAFR,MARCH1,PID1,ARHGEF10L,ACER3,SH3BP2,SLC11A1,ZCCHC24,RAP1GAP2,SULF2,FGD4,PLCB1,KIAA0930,TF,TIAM1,TLR4,TNFRSF1B,TPD52,TRIO,PLD4,CERS6,NLRP3" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K3 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.04E-02 1.00E+00 3.28E-02 2.99E-01 20 72 "ADCY8,CA4,HAPLN1,LRRC3B,HDAC9,FGF11,JPH4,CECR2,ZIC5,CDH20,CCDC80,PRTG,FXYD1,IRX1,NKAIN4,EMID1,SALL1,SOX10,FLRT1,ZIC2" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k2 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.04E-02 1.00E+00 3.28E-02 2.99E-01 20 72 "EPB41L5,AIF1L,ST3GAL6,SGIP1,GABRA4,SYT17,IGSF5,HP,SYT9,GDPD2,PTPRO,RIPOR1,FAM184A,DUSP15,EFHD1,DDN,TMEM150C,TNS2,TMEM178A,CERS6" Coexpression Atlas BM Top 100 - dorsal root ganglia BM Top 100 - dorsal root ganglia Body Map 1.04E-02 1.00E+00 3.28E-02 2.99E-01 20 72 "SORCS1,AKAP12,DRP2,ELAVL2,ELAVL4,FABP7,FGF13,MAP7D2,STMN2,MAP4,MATN2,COL28A1,NEFM,NEFH,PIRT,PRPH,TMEM255A,RET,TAC1,SLC17A6" Coexpression Atlas GSM538380_500 "alpha beta T cells, T.4Nve.PP, TCR+ CD4+ CD44low CD62Lhigh, Peyer's Patch, avg-2" "Immgen.org, GSE15907" 1.05E-02 1.00E+00 3.31E-02 3.02E-01 70 327 "ACTN1,NDRG3,NDRG2,ADD3,AXIN2,ESYT2,USP28,SFMBT2,ATM,ATP1B3,LRIG1,IPCEF1,KIAA0040,RIPOR2,TOX,KBTBD11,ATN1,RASGRP1,PHF20L1,RASGRP2,KIAA1109,NSG2,FYB1,FYN,RAPGEF6,GGT5,RAPGEF4,BACH2,ZDHHC15,AGFG1,IL6R,IL6ST,INPP1,ITPKB,HECTD2,SESN3,PDE3B,PDE4D,RETREG1,PACSIN1,SH3KBP1,PPP3CC,SYTL2,SIDT1,TTC13,CEP97,REV3L,RGS10,RAVER2,CLIP1,SATB1,SELL,GALNT10,SGK1,FAM102A,ST8SIA1,DZIP1,TET1,DOP1A,TNIK,SP4,KIF1B,TCF7,TGFBR3,ACTR6,RGMB,TRIO,RUNDC3B,RICTOR,KLHDC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k5 DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.06E-02 1.00E+00 3.33E-02 3.04E-01 24 91 "ADD3,PLEKHH1,NIPA1,CAST,B4GALT6,CNTNAP2,RABGAP1L,CPEB2,PRKAG2,PDLIM5,TRIM16,SDCBP2,ITIH2,MAOB,FA2H,PPP2R2B,SATB1,SH3BGR,SLC14A1,RAP1GAP2,WWC1,SYNPO2,UCHL1,SLC30A4" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_1000 dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse ST 1.0 1.06E-02 1.00E+00 3.33E-02 3.04E-01 24 91 "KDM5D,DDX3Y,CLU,FADS2,E2F6,PLXNC1,SORBS3,FAM198B,FGF13,AFF2,IQGAP2,GATM,PPARGC1A,GPM6B,LRRTM3,PAK3,RASGEF1B,MASP1,ROBO1,SOX6,SMOC1,THRA,ADAMTS9,WNK3" Coexpression Atlas gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_200 dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.06E-02 1.00E+00 3.34E-02 3.04E-01 10 28 "ASCL1,CCK,EDNRB,LMO1,NELL2,GDAP1L1,ELOVL2,SOX10,NUDT10,SYP" Coexpression Atlas gudmap_developingGonad_e14.5_ ovary_200_k1 DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.08E-02 1.00E+00 3.38E-02 3.08E-01 14 45 "LCORL,CHM,RBM39,GABRA4,CHIC1,KITLG,NASP,TMLHE,FNIP1,CPEB4,CBX5,R3HDM1,SSBP2,ADAMTS9" Coexpression Atlas gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k3_500 dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.08E-02 1.00E+00 3.38E-02 3.08E-01 14 45 "SEMA7A,DDX3Y,JAM2,CLU,DOCK4,PLXNC1,FAM198B,ACSL4,AFF2,FYN,IQGAP2,PAK3,RASGEF1B,SMOC1" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k3 DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.09E-02 1.00E+00 3.40E-02 3.10E-01 18 63 "PHYHD1,CACNA2D1,SEMA3D,PDLIM5,GFRA2,PCDH17,GHR,FERMT2,NFIA,PDE3A,PRRX1,REV3L,CAMSAP2,HHIP,ERCC6L2,RGMB,TRPS1,MSRB3" Coexpression Atlas BM Top 100 - trigeminal ganglia BM Top 100 - trigeminal ganglia Body Map 1.10E-02 1.00E+00 3.43E-02 3.13E-01 21 77 "SORCS1,PRX,AZGP1,DRP2,STMN2,ARHGAP19,MAP4,MATN2,COL28A1,NEFM,NEFH,HCN1,PIRT,PMP22,PRPH,TMEM255A,SHC4,TAC1,KCNK12,ZIC2,SLC17A6" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k4_1000 kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.10E-02 1.00E+00 3.45E-02 3.15E-01 68 317 "KLHL32,ADORA1,ZNF608,PCDH19,CEP126,VAT1L,BARD1,BCL7A,BLM,CACNA1G,SOCS6,SLIT2,TENM4,GREB1,ECE2,CENPL,GSDME,SV2B,RAB39B,EMX2,HSD17B14,EPB41,POLR1B,MEX3B,FOXM1,MPP6,MTHFD2,IGSF5,FAXC,TOX3,KDM2B,PSRC1,ADGRA3,CECR2,HTR2A,KIF5C,CLEC18A,TM6SF1,POC1B,MSI1,MYCN,NPY,PRTG,PMS2,SDK2,SPDL1,RBBP6,ROBO1,GLDN,PRR5L,CCDC112,ASRGL1,SH3BGR,SH3GL3,CNKSR2,SEPHS1,ATF7IP,CMTR2,SOX11,NUDT10,TACR1,CUX2,HEY1,TRPS1,SLC38A1,ADAMTS9,FZD3,NETO2" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k1 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.12E-02 1.00E+00 3.48E-02 3.18E-01 26 101 "EMILIN3,ADD3,USP31,CANX,CRHBP,VCAN,EDRF1,TM9SF4,SMC2,GABRA3,PCDH17,RAPGEF4,ZDHHC15,KIT,LIFR,NASP,NFIA,PCDH18,PEG10,C11orf87,CLASP2,EPB41L3,DNMBP,HHIP,RBFOX2,GOPC" Coexpression Atlas gudmap_kidney_adult_JuxtaGlom_Ren1_1000 kidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.12E-02 1.00E+00 3.51E-02 3.20E-01 156 801 "ACADM,NDRG2,KIDINS220,OSBPL6,ADGRF5,SPARCL1,ANK3,C6orf89,PKP4,DDO,APP,AQP6,ASPA,ATP1A1,SLC4A4,ALDH7A1,MYOM1,LDHD,CA4,CA12,CALB1,VSTM2A,MAP7,CLDN10,SLC16A4,REPS2,CDO1,ADGRG1,CHRNA4,NDST3,SLC22A6,CLU,TPP1,CLTB,ABCG2,ARHGEF6,MFSD4A,ENTPD4,OSBPL3,CTH,ARHGAP24,ACY3,DGKB,AIF1L,SV2A,CCDC3,EBF1,USH1C,SNX29,EDNRB,SGK2,FAM13A,AASS,RCAN2,DMTN,ENPP6,SLC43A2,EPS8,ERBB4,ETV1,PIPOX,FABP7,EFEMP1,FCGRT,FGF1,FHL1,FOLH1,FUT9,PHYHIPL,GABRB3,IQGAP2,ACSS1,STARD10,GATM,IGSF5,ALDH1L1,GHR,PPARGC1A,GK,GLDC,GPD1,GPM6A,RAPGEF4,GSTT2,HLF,HNMT,IDH3B,SCIN,KCNJ10,KCNJ16,KHK,LAMP2,C2orf80,AQP11,MIA2,MYO6,IGSF11,OGDH,PAH,PC,PDE1A,PDE3A,ENPP2,PFKP,PGAM2,SERPINE2,SERPINI1,MINDY2,PPP1R1A,RANBP3L,PRODH,CNNM2,SYTL2,PTH1R,PTPRB,ACSM5,PLEKHB2,SLC6A15,SUGCT,RERGL,LRRK2,PTGR2,HOGA1,SCN2A,SCP2,KIF21A,FAM81A,SLC2A5,SLC6A8,SLC8A1,SLC15A2,EFHD1,CPEB4,CABCOCO1,SPP1,TEX2,PBLD,NXT2,ADHFE1,SYNE2,PLCB1,ATP11A,SEMA4A,AHCYL2,TEK,AKTIP,HEY2,TNS1,NPL,TRPC1,CA14,UGT8,DNAJC12,VLDLR,SLC13A3,DOCK8" Coexpression Atlas gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200 dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200 Gudmap Mouse ST 1.0 1.14E-02 1.00E+00 3.57E-02 3.25E-01 22 82 "ARHGAP20,LTBP4,ADAM23,CACNA2D1,CBLN1,SLIT2,VCAN,EDNRA,EGFR,LRRC17,GFRA2,FREM1,GUCY1A1,GUCY1B1,LAMA2,PDGFRA,PLTP,FAT3,PTCH1,ROBO2,HHIP,STOX2" Coexpression Atlas GSM538234_500 "Myeloid Cells, DC.103+11b-.Lv, CD45+ CD11c+ MHC-II+ CD11b low CD103+, Liver, avg-2" "Immgen.org, GSE15907" 1.15E-02 1.00E+00 3.58E-02 3.26E-01 85 409 "CPNE2,FMNL2,ADORA3,ADRB2,ADGRF5,ALCAM,AMPD3,FGD2,APP,SHTN1,TMEFF1,ARHGAP5,ADAM23,ST3GAL5,C1QC,CACNA1E,CD86,CD81,JAM2,LY86,FAM149A,ZNF385A,CDC42BPB,CSF1R,CSF2RA,CST3,SDC3,CTNND1,CYBB,HDAC9,MYADM,DAPK1,DBN1,SRGAP3,ARRDC4,EBI3,PLXNC1,PLEKHO1,EPS8,F8,OLFM1,NEK6,GATM,RAB30,MAP4K5,IRF8,IFI16,LRRC25,DOCK7,JAK2,KIT,LIFR,MYO9A,CLEC9A,NUCB2,PBX1,PDE1B,CDK14,PRKAB2,RASGEF1B,PTPRB,PID1,C1orf54,ROGDI,SNX22,LRRK2,RTN1,MRAS,SLC8A1,CCDC88A,SLC11A1,TRERF1,SULF2,SEPT3,KIAA0930,TCF7L2,TEK,TRPM2,TUBB2A,CADM1,WNK1,PMEPA1,PLD4,NLRP3,PIANP" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500_k3 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.16E-02 1.00E+00 3.61E-02 3.29E-01 19 68 "LCORL,CHM,NMT2,RBM39,FGFR1OP2,CALCRL,SCML2,ILDR2,MMP16,NASP,CNOT4,TMLHE,FNIP1,ZC3H13,SYNE2,R3HDM1,ADAMTS9,SNX27,GAN" Coexpression Atlas gudmap_developingGonad_P2_testes_200 DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.16E-02 1.00E+00 3.62E-02 3.30E-01 38 161 "TKTL1,ARID1A,TMCC3,ADD1,NR0B1,C1QTNF3,AMH,SEMA7A,MMD2,CBLN1,ADGRG1,CLU,RNF14,DBI,PLPPR4,DTNA,EBF1,EDNRA,PLXNC1,EPB41L2,LRRC17,GATM,GPM6B,GPR37,MAEL,HSD17B1,IL6ST,MYO7A,NFIX,PAK3,SEMA5B,MEG3,ARX,EFHD1,ACSBG1,PUM2,HHIP,TST" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.17E-02 1.00E+00 3.63E-02 3.31E-01 13 41 "INA,ST8SIA3,REEP2,TUBB4A,CECR2,SHISAL1,PRTG,MAGEL2,RELN,SALL1,WASHC4,ZIC2,ZBTB16" Coexpression Atlas gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5 DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.17E-02 1.00E+00 3.64E-02 3.31E-01 37 156 "OGT,ANK3,APC,BMP7,CANX,CLCN3,RBM39,FGFR1OP2,ARHGAP24,DDX46,ARNT2,SEMA3D,EIF5,EIF1,SYNCRIP,SMC2,PDLIM5,PPARGC1A,CNTRL,GRB10,ICA1,KIF5C,NASP,NEK1,PIK3C2A,KANSL1,REV3L,CLIP1,RUFY2,STX1A,CAMSAP2,WWC1,ERCC6L2,SSBP2,VLDLR,ZNF23,NUP214" Coexpression Atlas gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_100 dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.18E-02 1.00E+00 3.66E-02 3.34E-01 6 13 "NR0B1,PPP4R4,DCLK1,DRP2,TEX15,ACTR6" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K2 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#2 FaceBase_RNAseq 1.18E-02 1.00E+00 3.68E-02 3.35E-01 23 87 "PTCHD1,C1QTNF1,FGD2,FGF17,LRBA,CBARP,TJP2,C8orf34,SLC43A2,RRAGB,CLVS1,FGF12,PCDH11X,IL17D,MEIS1,SERPINE2,EPB41L4B,MAPK12,CCDC92,SOX2,WWC1,WSCD1,CA14" Coexpression Atlas Facebase_RNAseq_e10.5_Olfactory Pit_500_K2 FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.20E-02 1.00E+00 3.73E-02 3.40E-01 17 59 "ATP2B1,INA,TUBB4A,TOX3,CECR2,SHISAL1,NRCAM,CEP97,SALL1,MAPK12,SMARCA4,BEX1,MTCL1,WSCD1,WASHC4,BEX4,TST" Coexpression Atlas gudmap_developingGonad_e14.5_ epididymis_500_k1 DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.21E-02 1.00E+00 3.75E-02 3.42E-01 15 50 "PCDH19,GSDME,MEX3B,MYBPC1,MAPK8,ROBO2,SFPQ,ZKSCAN3,RBM26,RGL1,KLHL4,CLASP1,ASXL3,TPM1,WNT7A" Coexpression Atlas gudmap_developingLowerUrinaryTract_adult_bladder_200_k1 DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.21E-02 1.00E+00 3.75E-02 3.42E-01 15 50 "MFAP3L,CHRDL1,MRVI1,NRN1,CAP2,DNER,KCNA1,KCNF1,MBP,TTLL7,SCN7A,SLC14A1,SYN2,AGMO,DOCK8" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K2 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#2 FaceBase_RNAseq 1.21E-02 1.00E+00 3.76E-02 3.43E-01 67 313 "NDRG2,PLEKHG5,PTCHD1,MTUS1,C1QTNF1,APOC1,CACNA1B,MAP7,CBARP,MYL6B,LETMD1,PPP6R2,MYADM,SPOCK2,C8orf34,RABGAP1L,HEYL,SEMA3D,EGFR,RPS6KC1,FGF12,PCYOX1,SEMA6C,SEMA4D,STAMBP,GAD2,STARD10,PCDH17,NR3C1,FAM107A,FRMD3,LRRC75A,KCNK1,ADAM11,IL17D,MEIS1,MOV10,SAMD14,HS6ST3,NNAT,GPR173,SERPINE2,SMOX,FXYD1,TATDN3,PRODH,PTPRG,RAB3A,LGR4,ATXN7,FERMT1,KIF16B,CLSTN1,DOK5,UNC5B,INKA2,MCF2L,MGRN1,PCDHGA2,TEX15,SLC44A1,ENHO,TNNT1,TOM1L2,PORCN,NDRG4,SH3GLB2" Coexpression Atlas gudmap_kidney_adult_GlomCapSys_Tie2_k2_1000 kidney_adult_GlomCapSys_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.22E-02 1.00E+00 3.77E-02 3.44E-01 24 92 "TAOK1,ARRB1,CFLAR,THSD7A,CD81,CLOCK,MYADM,EML1,CEP85L,CORO2B,ST3GAL6,FERMT2,MAPT,CCSER2,RIPOR1,ZDHHC14,FAM81A,CPEB4,LMBRD1,PSD3,ARHGEF12,TNS2,TJP1,MSRB3" Coexpression Atlas GSM791126_100 "Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3" "Immgen.org, GSE15907" 1.22E-02 1.00E+00 3.77E-02 3.44E-01 24 92 "ZNF608,CDC42BPA,PRC1,ADGRG1,FADS2,CTNND1,CALCRL,MED12L,NBEA,GCNT2,GRB10,GUCY1A1,HLF,ICA1,KIT,LMO2,MEIS1,MYCN,PBX1,ANLN,TET1,TEK,TIE1,NETO2" Coexpression Atlas gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_100 dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.22E-02 1.00E+00 3.78E-02 3.45E-01 20 73 "NR0B1,CALB1,CDH10,VCAN,DOCK4,DRP2,PLXNC1,GABRA4,FREM1,PCDH11X,KLHL23,MEIS1,NEFM,PDGFRA,PCDH18,PRRX1,TMEM255A,ADGRL3,KLHL4,ACTR6" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-1_E18.5_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-1_E18.5_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes by Age group - subtype vs all) 1.23E-02 1.00E+00 3.80E-02 3.46E-01 48 213 "NDRG2,SPARCL1,LTBP4,TMEM263,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,FHL1,UBE2E3,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,PBX1,PDGFRA,SERPINE2,ZFYVE21,FXYD1,PMP22,SEPT4,NKAIN4,MAPK7,PTCH1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,USP22,TGFBR3,HHIP" Coexpression Atlas Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-1_Top_200_Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast_Subtype_MyoFB-1_Top_200_Genes LungMap.net (mouse fluidigm; Major cell types and subtypes - subtype vs all) 1.23E-02 1.00E+00 3.80E-02 3.46E-01 48 213 "NDRG2,SPARCL1,LTBP4,TMEM263,RUNX1T1,CD81,CDO1,SLIT2,CNN3,MAGED1,CP,AKAP12,VCAN,DOCK4,ZEB2,EDNRA,PCOLCE2,LRRC17,ETV1,FHL1,UBE2E3,DKK3,FREM1,FERMT2,GPM6B,GRB10,GSN,GUCY1A1,GYG1,IGF1,PBX1,PDGFRA,SERPINE2,ZFYVE21,FXYD1,PMP22,SEPT4,NKAIN4,MAPK7,PTCH1,ROBO2,TNFRSF19,LIMCH1,PALLD,PDLIM2,USP22,TGFBR3,HHIP" Coexpression Atlas GSM605796_500 "gamma delta T cells, Tgd.vg2-.Sp.TCRbko, TCRd+ Vg2- CD44-, Spleen, avg-3" "Immgen.org, GSE15907" 1.25E-02 1.00E+00 3.86E-02 3.52E-01 84 405 "ACTN1,ARID1A,ADD3,AXIN2,ADORA2A,ESYT2,PITPNM2,KCNAB2,DGKZ,BAIAP3,ARHGEF1,CDC25B,CHN2,LRIG1,IPCEF1,HDAC9,RIPOR2,HDAC4,TOX,SPOCK2,PITPNC1,DNAJC6,KBTBD11,DOCK2,RASGRP1,TNK2,FGF13,MEX3B,AGAP2,NSG2,SARAF,FYN,TRAF3IP2,B4GALNT1,RAPGEF4,PADI2,BACH2,ZDHHC15,AGFG1,IL6ST,ITPKB,JAK1,KCNC1,KIT,KLRC2,SESN3,NEFH,ZNF827,PDE2A,PDE3B,ZDHHC8,ABCB1,PIK3CD,PLEC,SLC25A23,PACSIN1,SH3KBP1,POU6F1,PPP3CC,SYTL2,SIDT1,SATB1,PEAR1,SELL,GALNT10,RASA3,FAM102A,ST8SIA1,DZIP1,SLC14A1,ATF7IP,TET1,TNIK,KIF21B,ACSBG1,SYT11,TCF7,AKNA,TRIO,RUNDC3B,SLAIN1,WIPF1,PMEPA1,SPATA13" Coexpression Atlas ratio_MESO_vs_SC_1000_K5 ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5 PCBC 1.26E-02 1.00E+00 3.90E-02 3.56E-01 99 487 "KCNH8,CSMD3,SORCS1,ADORA1,NR0B1,PCDH10,TRMT9B,APOC1,LGR5,ARHGDIG,ARSE,FGF17,BMP7,ST3GAL5,CASTOR3,C5,MYRF,CFAP410,CCKBR,CDH2,CNR1,COL4A5,COL9A2,NRG2,TENM4,CNTNAP2,PLXNA4,PYGO1,ARHGAP24,SV2B,SPOCK3,DSCAM,FAM135B,ELAVL4,ERBB4,RASL12,AMOTL2,C1orf61,RASL10A,TBR1,DENND2A,GATM,FREM1,PCDH17,GPM6A,GPR37,TMEM121B,GRIK3,FAM222A,HAS2,LRRTM1,CDH20,KCNF1,KCNH1,CLVS2,LIFR,MATN3,MOBP,MYT1,NODAL,SETD4,OLR1,OXTR,CNTN3,PAX6,PCDH8,ENPP2,SERPINE2,PDZRN4,MAPK10,LAMA1,ELOVL2,FAM184A,WLS,RXRG,ST8SIA1,ANKRD6,SLC1A2,SLC9A5,SOX10,MCF2L2,NFASC,SSTR2,SSPO,TMEM150C,PHF24,FAM189A1,LEFTY2,PIK3R5,SEZ6L,TRH,TRO,TRPM2,TTC3,RPRM,KCNK12,FMN2,PLPP4,ANKS1B" Coexpression Atlas GSM605853_100 "Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3" "Immgen.org, GSE15907" 1.28E-02 1.00E+00 3.93E-02 3.59E-01 21 78 "C1QC,CD86,DGKI,LY86,CSF1R,SDC3,SIRPA,IGSF6,FCGR3A,GFRA2,HPGDS,IGF1,KCNJ16,MYO9A,P2RY13,PILRA,RASGEF1B,SEMA6D,SLC11A1,TF,TLR4" Coexpression Atlas gudmap_developingGonad_e18.5_epididymis_500_k2 DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.29E-02 1.00E+00 3.96E-02 3.61E-01 18 64 "ADD3,TAOK1,C1QTNF3,LTBP4,DDX3Y,PLCXD3,RIPOR2,ELN,LRRC17,CSDC2,KLF12,MAOB,MATN2,NFIA,NFIX,HHIP,NR2C2,PMEPA1" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_500 kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.30E-02 1.00E+00 4.02E-02 3.66E-01 80 384 "KCNH8,KLHL32,PCDH19,SEMA6A,LGR5,BARD1,BCL7A,PROM1,BMPR1B,CALB1,CD38,B4GALT6,SLIT2,HAPLN1,FAM169A,CTNND2,TOX,DUSP9,EDNRB,SEMA3D,CACNG7,PLEKHA1,EMX2,EN2,SH3YL1,ACSL4,NOP56,GAP43,IGSF5,GFRA1,MAP7D2,GNG3,GRIK2,HAS2,HMGB1,ZDHHC15,LIX1,KIF5C,KIT,LMO2,GPR155,KITLG,SAMD5,THYN1,TCEAL5,NASP,PRTG,PDE3B,PRRX1,SEPT4,FAT3,SPDL1,ZIK1,EML5,PTPRZ1,TMEM255A,RET,MORC4,FIGN,NUDT11,ROBO2,FHOD3,PREX2,SOX11,BEX1,SYT11,NUDT10,TMEM150C,TAF9,KLHL4,CUX2,TEK,BEX4,CA14,CADM1,UCHL1,SLAIN1,VSNL1,SLC38A1,SOCS4" Coexpression Atlas gudmap_kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_Scamp_1000 kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_StemCellamp_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.31E-02 1.00E+00 4.02E-02 3.67E-01 121 609 "DPF1,RBM10,EMILIN3,ELFN2,ADORA2A,PWWP2A,ADRA1D,SPARCL1,DOC2A,LRFN1,ANK1,PPFIA4,SUGT1P4-STRA6LP-CCDC180,AMER3,DACT3,ATP1A3,ALDH7A1,BAIAP3,CDK5R2,CACNG1,THSD7A,SYT6,P2RX6,CBFA2T2,GPR37L1,CBARP,CLU,QKI,IGLON5,COL9A2,COL9A3,COL11A2,FAM171B,ARHGEF4,HDAC9,ARHGAP32,TOX,CCDC3,GRIN3A,HS3ST2,MAMLD1,DYRK1A,EBF1,FAM135B,PHF20L1,EGR3,DENND4A,REEP2,GTF2IRD2,FOXG1,KHDRBS3,NKX6-2,TUBA8,GLS,ATF7,GRIK5,SERP2,SLC2A6,TMEM179,WIF1,IGFBPL1,LRRC75A,BTBD17,ITPKA,KCNB1,KCNK3,PPM1L,MMP16,MMP17,MYO9A,NCF2,GPR88,PDYN,SERPINE2,SNX10,FXYD1,NXPH1,POU3F2,VSTM2L,C1orf54,RBBP6,KIF7,PAQR6,NTNG1,SNCB,MAPKBP1,TMCC1,SOX3,LHFPL4,ERC1,ARHGAP26,NFASC,SST,SSTR1,LARP4,LRRC4,SYNE2,ADAMTS17,SYT4,SZT2,DNAH7,TIAM1,KCTD2,TNS1,CHST5,ZNF384,TRH,TRIO,FLRT1,PLEKHH2,MGAT5B,PLPPR2,REEP1,SLC30A3,GDPD5,STMN4,ADAMTS9,SLC17A7,WNK2,RSPRY1,SSPN" Coexpression Atlas gudmap_developingGonad_e16.5_epididymis_500_k3 DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.32E-02 1.00E+00 4.07E-02 3.71E-01 14 46 "TAOK1,LCORL,CHM,NMT2,RBM39,SCML2,ILDR2,KIF3A,CNOT4,PDPK1,TMLHE,FNIP1,SYNE2,ADAMTS9" Coexpression Atlas gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_1000_k4 DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#4_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.32E-02 1.00E+00 4.07E-02 3.71E-01 14 46 "SORCS1,PCDH10,DNM1,FABP7,FOXF2,SGIP1,GABRA1,MYOZ2,ALDH1L1,GFRA2,PAH,ZFHX4,SCN3B,ZIC3" Coexpression Atlas gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_100 dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.33E-02 1.00E+00 4.07E-02 3.71E-01 11 33 "CALB1,PLXNA4,DOCK4,MAGI2,DRP2,EMX2,GABRA4,KCND2,PCDH18,ADGRL3,TNNT1" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k2_100 kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.33E-02 1.00E+00 4.07E-02 3.71E-01 11 33 "CRYM,SNCAIP,VCAN,SNAP91,EYA1,FGFR1,HAS2,CNTN3,PENK,MDGA2,SALL1" Coexpression Atlas gudmap_kidney_adult_RenMedVasc_Tie2_500 kidney_adult_RenMedVasc_Tie2_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.34E-02 1.00E+00 4.11E-02 3.75E-01 86 417 "CPNE2,NDRG2,USP31,HECW2,ADGRF5,SPARCL1,SEMA6A,AMPD3,SEMA7A,APBB2,APP,DDX3Y,ADAM15,NRP2,CA8,CH25H,LDB2,FMNL3,CD38,CHN2,JAM2,PPP1R16B,DOCK4,PITPNC1,NR1D2,GNE,ECM2,EBF1,EDNRB,SEMA3D,TMTC1,CALCRL,F8,ATP8A1,ST3GAL6,KIAA1109,FLT1,ST6GALNAC3,ERAP1,INPP5K,PCDH17,GGTA1P,GPM6A,RAPGEF4,NR3C1,IFI16,IGF1,SCIN,ITPKB,STXBP5,LMO2,TM6SF1,MEF2C,MEIS2,CD200,MYO6,NFE2L2,PBX1,PDE2A,PLTP,MINDY2,SNRK,PTPRB,RIPOR1,LRRK2,SGK1,PREX2,SMTN,SLC14A1,SLCO1A2,LIMCH1,LMBRD1,RGL1,PLCB1,ROBO3,KLHL4,TCF4,SYNE1,TNS2,TEK,TIE1,TLR4,TNS1,TRPC3,AGMO,PLSCR4" Coexpression Atlas PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05 Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.34E-02 1.00E+00 4.12E-02 3.76E-01 203 1071 "ABAT,ABHD6,NDRG2,AGT,C1QTNF3,AMPD2,BIN1,C6orf89,APLP1,GPAM,VAT1L,SEMA4G,TMEM263,ASGR1,ASPH,ALDH4A1,ATP6V0A1,BCHE,PROM1,AP1M1,RAB29,SLC16A4,SCARB1,ARHGAP33,ADGRG1,SLIT2,IGFBP7-AS1,CLCN3,CLU,TJP2,FADS2,AKAP7,IGDCC3,NECTIN3,ZNF385A,CPS1,HAPLN1,CRYM,CSF3R,MICAL2,CST3,TCAF1,SIRPA,RHOBTB1,FAM107B,DMD,RCAN1,TOM1,DUSP9,EDIL3,EDN1,ANKRD46,HIPK3,KLHL5,FAM13A,EGFR,MBNL2,ELN,HSD17B14,CLVS1,FAM198B,SH3YL1,PTK2B,EFEMP1,ST3GAL6,TOMM40L,FCGRT,FDFT1,TESK2,SLC9B2,ZBED3,SDCBP2,NEK6,IQGAP2,TMEM8B,STARD10,NEU3,SESN1,GHR,GJB1,RND1,GLDC,PCSK1N,GPD1,GSN,ZHX1,HMGCL,HMGCR,C2orf72,IGSF1,IL6R,IL6ST,IL11RA,ITIH2,ITPKA,JAK1,SLC35G1,KCNJ16,TMEM110-MUSTN1,LAMP2,SFXN5,LSS,MAOB,MATN2,MDFI,MIA2,SCAMP5,MITF,SESN3,CCDC80,NRBP2,MTTP,MYL3,MYO9A,NPR2,NRGN,PAH,PBX1,PC,PCSK5,PDE3A,PDE3B,PDGFRA,ENPP2,PFKFB4,PFKP,CDK14,PGAM2,SERPINI1,PIK3R1,SMOX,PCDH18,PLTP,SCHIP1,PPARA,PPP1R1A,SMIM10L2B,MASP1,KLK6,SLC22A23,PTCH1,RAB3IL1,RAP1GAP,BEND5,PRRT2,RGS3,ARHGEF10L,ROBO2,RXRA,DGLUCY,HOGA1,IL17RB,ASRGL1,SGK1,MYO18A,HKDC1,SMTN,SIRT2,SCMH1,EFHD1,SLN,LIMCH1,SNCA,PDZRN3,ZSWIM8,TEX2,IDI2-AS1,UNC5B,ITPRID2,APOM,RGL1,ADHFE1,VPS13A,COBL,TAC3,PDLIM2,WWC1,SZT2,VWCE,TF,TGFBR3,AKTIP,AMACR,TST,TUB,FLRT2,PLPPR2,VAV2,TOM1L2,MICAL1,VSNL1,ELFN1,ATP6V0E2,CRB2,REEP1,ZNF189,RNF103,TMEM178A,SEMA3B,ST7,MARCH8,NHSL1,SENP7" Coexpression Atlas facebase_RNAseq_e9.5_OlfPlac_2500 facebase_RNAseq_e9.5_OlfPlac_2500 Gudmap RNAseq 1.35E-02 1.00E+00 4.13E-02 3.76E-01 301 1633 "CPNE2,ACHE,ACLY,TMCC3,AXIN2,PLEKHH1,KIAA1211,AP1B1,KLHL13,PCDH19,C1QTNF1,BCAR3,ZNF687,DOC2A,TRMT9B,ANK3,FGD2,PI16,MYH7B,EPB41L5,DGKZ,NT5C3B,SHTN1,TMEFF1,ARRB2,ATM,NOL4,BCHE,NRP2,BLM,ZNF599,PROM1,BMP7,WASF1,CA4,CA12,CACNB2,HAP1,PTBP2,BRSK2,HIP1R,MAP7,SHISA7,MTMR7,CBFA2T2,ARHGEF2,CDH2,LRWD1,TBRG4,CACNA2D2,ADGRG1,CBARP,JAM2,NRXN3,KIAA1549L,MYL6B,TMEM59L,TJP2,FAM19A5,HOMER3,CNTFR,PCYT1B,COL9A1,SLC4A7,BAG4,IGDCC3,ZNF385A,HAPLN1,ABCG1,CRYM,OSBPL3,PLCH2,CNTNAP2,PLXNA4,FAM169A,GREB1,KATNAL2,AIF1L,DNAJC6,MED24,DLG3,USP3,CDON,CPEB2,DTNA,DUSP9,FARSB,E2F5,TSPAN5,RBM12,YAF2,EFNB3,EIF4G1,ELAVL2,ELAVL4,RGS17,EMX2,EPB41,DMTN,EPHB1,ANKRD13B,EPS8,ERBB4,ETV1,ADGRV1,EYA1,REEP2,TUBB4A,CEP78,POLR1B,SPSB4,FGF12,CAMSAP1,FHL1,PCYOX1,SEMA6C,SYT3,NELFCD,POMT1,TMEM107,CINP,PDLIM5,KHDRBS3,FUT9,PHYHIPL,B4GALNT1,MTHFD2,SYT17,STARD10,GART,WASF3,TCERG1,GLDC,DBF4,GLI2,GLRB,TOX3,GLUL,STARD3,KIAA1958,GNG3,LNX1,PSRC1,GPD2,B4GALNT4,CECR2,GRIA4,RFFL,GRIK2,ZNF496,RNF165,PSIP1,FAM107A,FAM222A,CELF3,HAS2,TOX2,FRMD5,ARHGAP19,HSF2,LRRC75A,HSP90AA1,SHISAL1,TUBB2B,METTL21A,KCNH2,KCNK1,KIF5C,KIT,MAOB,MAP2,AQP11,MBP,ADAM11,MDFI,MEIS1,MEST,KCTD6,AFDN,MSI1,TAGLN3,MXI1,MYCN,NAP1L1,NASP,RCOR2,NNAT,VWA2,NRCAM,KSR2,ODF2,CDK18,PDE3B,PDPK1,NOMO2,SNX10,RETREG1,PKM,GPSM2,EPN1,PLP1,SLC25A23,PLXNB1,PSAT1,PPP2R2B,PPP5C,MAPK4,PRODH,GDPD1,LAMA1,SIDT1,UHRF1BP1,ELOVL2,ZIK1,PTPN13,EML5,NKAIN1,RAB3A,CCDC40,SUSD4,ZMAT4,DPF2,FIGN,RFX3,NUDT11,RAVER2,GSTCD,PRR5L,ACER3,RPS6KA2,LGR4,HUNK,SOX8,RTN1,TRAPPC13,SALL1,MAPK12,SATB1,SOX6,SCG5,KIF21A,FERMT1,SHMT2,ST6GAL1,CCDC92,PKNOX2,SLC15A2,CXXC4,IFT122,INAVA,SOX2,KIF21B,SOX11,BEX1,SPTB,KANK1,TMEM150C,ANKRD28,MMS19,WWC1,WSCD1,TCF7,DOCK9,SIRT1,ITGB3BP,HEY1,HEY2,BEX4,TPD52,TRPC1,CA14,TMEFF2,HIRA,UBC,CADM1,AMOT,DNAJC12,SLAIN1,FAM181B,USP1,VAV2,NSD2,KLC2,ZFP41,ZBTB16,DPYSL5,TFIP11,MEIS3,DHX33,SLC38A1,RGMA,TUBA1A,ADAMTS9,NAV2,PCBP4,WNK2,FZD3,TTC7A,AP3B2,CPNE4,SPATA13" Coexpression Atlas Lungmap Mouse Lung PND1 MatrixFB Subtype MatrixFB-A Lungmap Mouse Lung PND1 MatrixFB Subtype MatrixFB-A Lungmap CCHMC 1.36E-02 1.00E+00 4.14E-02 3.78E-01 59 272 "NDRG2,SPARCL1,ALCAM,ATP1A2,ATP2B1,CACNA1D,CD81,CDK11B,CDO1,NIPBL,CP,NCOR1,MATR3,DAPK1,YTHDC1,HP1BP3,EDNRA,SH3GLB1,MBNL2,SRRM1,DLC1,FGFR1,FGFR3,UBE2E3,FYN,SESN1,GFRA2,GLUL,GOLGB1,GSN,IL6R,KTN1,LAMP2,MARK3,NAP1L1,NFIA,PIK3R1,FXYD1,SEPT4,PKN2,ARID4A,RBBP6,SFPQ,ABLIM3,PREX2,EPN2,LIMCH1,PALLD,KIF1B,PRRC2C,TACC1,ANKRD12,TGFBR3,HHIP,ZFP91,TNS1,TPM1,VLDLR,ZBTB16" Coexpression Atlas gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100_k5 DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.36E-02 1.00E+00 4.14E-02 3.78E-01 7 17 "FOXF2,MEGF10,IFI16,KCNK2,RSPO2,NDP,ZFHX4" Coexpression Atlas gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_100 dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.36E-02 1.00E+00 4.14E-02 3.78E-01 7 17 "ARHGAP20,CBLN1,VCAN,EDNRA,FREM1,GUCY1A1,PDGFRA" Coexpression Atlas gudmap_developingGonad_e12.5_testes_k4_200 DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.36E-02 1.00E+00 4.14E-02 3.78E-01 7 17 "TUBB2B,NASP,NNAT,SNRPN,SOX2,RBM26,PCBP4" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k1_200 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.36E-02 1.00E+00 4.14E-02 3.78E-01 7 17 "IGSF5,GFRA1,HAS2,PRTG,FAT3,CUX2,CADM1" Coexpression Atlas DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_100 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.36E-02 1.00E+00 4.14E-02 3.78E-01 7 17 "EPHA5,FOXF2,DNER,IFI16,RSPO2,ZFHX4,SCN3A" Coexpression Atlas Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K2 FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#2 FaceBase_RNAseq 1.36E-02 1.00E+00 4.14E-02 3.78E-01 19 69 "ACTN2,APOC2,ARRB2,ZNF599,HPCAL4,FYB1,LIX1,GPR155,MID1,BCO1,CLEC9A,PILRA,STRC,REV3L,C11orf87,TMOD1,LAMP5,PMEPA1,SENP7" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5 DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.36E-02 1.00E+00 4.14E-02 3.78E-01 19 69 "USP31,APC,NRP2,CRHBP,TENM4,VCAN,IQGAP2,GFRA1,PCDH17,BACH2,NFIA,PRRX1,REV3L,C11orf87,EPB41L3,HHIP,RBFOX2,RGMB,NUP214" Coexpression Atlas Facebase_RNAseq_e8.5_Floor Plate_500_K1 FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#1 FaceBase_RNAseq 1.36E-02 1.00E+00 4.14E-02 3.78E-01 19 69 "CA4,CBLN1,CHRDL1,ST8SIA3,PIPOX,SYT3,CECR2,MYCN,PRTG,GDPD2,FIGN,BEX1,AJAP1,MTCL1,ROBO3,WASHC4,BEX4,ZIC2,ZBTB16" Coexpression Atlas PCBC_ratio_DE_from-ESC_vs_DE_from-OSKM_cfr-2X-p05 Endoderm Differentiated Cells-reprogram_NA_vs_Endoderm Differentiated Cells-reprogram_OSKM-Confounder_removed-fold2.0_adjp0.05 PCBC_AltAnalyze 1.39E-02 1.00E+00 4.24E-02 3.86E-01 10 29 "CALB1,LARGE1,CRMP1,CCDC3,ZNF559,NEFM,RASGEF1B,RET,SPP1,ZNF138" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#3 FaceBase_RNAseq 1.43E-02 1.00E+00 4.34E-02 3.96E-01 66 310 "ARRB2,ADAM15,CALM1,CBLN1,INA,LRRFIP1,LRWD1,CIART,BAG4,NCOR2,PPP1R16B,CTIF,SIRPA,ELMSAN1,FBXL5,CHRDL1,TOM1,FIS1,GOLT1B,ST8SIA3,TSPAN5,FCF1,COPS4,PLEKHA1,PIPOX,ECSIT,REEP2,TUBB4A,OLFM1,FOXM1,SALL3,GFER,TXNL4A,TOX3,CECR2,BVES,SHISAL1,LRRTM3,LYPLAL1,LDLRAD3,AFF1,MRPL42,CHAMP1,PRIMPOL,TMEM104,TTC13,YJEFN3,FAM192A,RMI1,SALL1,MAPK12,GALNT10,SEC31A,SNRPN,LRRC4,ROBO3,WWC1,WSCD1,WASHC4,OBSL1,GORASP1,SLAIN1,VAV2,SPHK2,NT5M,AMN1" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k5_100 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.43E-02 1.00E+00 4.35E-02 3.96E-01 8 21 "BACH1,RUNX1T1,CDH10,MEX3B,MEIS2,NASP,GPR85,KLHL4" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500_k3 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#3_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.43E-02 1.00E+00 4.35E-02 3.96E-01 9 25 "AMPH,CRYM,SNAP91,EYA1,TVP23A,HAS2,PRTG,MAPK12,LRP8" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500 facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500 Gudmap RNAseq 1.43E-02 1.00E+00 4.36E-02 3.97E-01 226 1204 "PLEKHH1,KIAA1211,KLHL13,HACE1,KIAA1324,PDZD4,AMPH,LRCH2,MYH7B,EPB41L5,VAT1L,BCAS1,SHTN1,TMEFF1,ARHGDIG,CAPRIN2,ATM,CADM3,KIF1A,BARD1,BCHE,NRP2,ZNF599,PROM1,OSGIN2,WASF1,MYRF,CA4,CA12,THSD7A,PTBP2,BRSK2,MAP7,SHISA7,MTMR7,CDH2,LRWD1,CACNA2D2,NRXN3,CLCN3,FAM19A5,C4orf33,CNTFR,SLC4A7,BAG4,NECTIN3,SLC35F1,FAM171B,CRMP1,CNTNAP2,FAM169A,CTH,GREB1,CTNND2,TMEM170A,TOMM20,AIF1L,DMD,E2F5,SEZ6L2,TSPAN5,EDN1,EFNA2,LPAR6,ELAVL2,PLEKHA1,EMX2,ENO2,EPHB1,RTN3,CEND1,EXTL2,ADGRV1,REEP2,TBC1D16,TUBB4A,CEP78,SPSB4,FGF13,FHL1,ZMYND15,NOP56,SYT3,CINP,FAM49B,PRELID3A,FUT9,PHYHIPL,GART,RUNDC3A,GLDC,DBF4,TOX3,CBX1,GNG3,GPD2,CCDC184,GPR19,LPAR4,CECR2,STMN2,GRIA4,GRIK2,RNF165,PSIP1,CELF3,TOX2,FRMD5,HLF,CFAP126,HSF2,HSP90AA1,LRRCC1,LIX1,LRRTM3,SLC35G1,KCNK1,IPO5,KTN1,CAMK2N2,LMO1,MAOB,MAP6,MAT2A,AQP11,MEST,MIA2,MSI1,MYCN,NAP1L1,NASP,RCOR2,VWA2,NOVA2,NRCAM,PAK3,PDE3B,PDE1B,FAM98B,OLA1,SNX10,PKM,PSAT1,POLR2F,FSD1,PPP1R1A,PKIA,PRKCB,MAPK4,RELN,GDPD2,ELOVL2,SPDL1,ZIK1,PTPN13,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,FIGN,NUDT11,RPL15,RPL38,ACER3,RTN1,SALL1,MAPK12,LRRTM4,FAM19A1,ZFP2,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,FHOD3,CCDC92,ZNF365,PPP4R3A,PKNOX2,EFHD1,KDM4B,SOX2,SOX11,BEX1,PBLD,ZC4H2,SYT11,MTCL1,WWC1,WSCD1,CUX2,C18orf54,ITGB3BP,AKTIP,RELL2,ACTR6,BEX4,RGMB,PRMT8,CA14,CADM1,RPRM,UBE3A,SLAIN1,NSD2,XPO1,KCNT2,ZFP41,SLC26A10,ZBTB16,TMEM237,DPYSL5,SMARCAD1,SLC38A1,RGMA,STOX2,PCBP4,WNK3,AMN1,FZD3,PHTF2,NETO2,SPATA13" Coexpression Atlas Facebase_ST1_e8.5_NeuroEpith_HindBrain_500 e8.5_NeuroEpith_HindBrain_top-relative-expression-ranked_500 FaceBase_ST1 1.44E-02 1.00E+00 4.36E-02 3.97E-01 90 440 "ACADM,NDRG3,FZD9,VAT1L,PDXK,ATP2A2,MTMR9,FGF17,PRMT9,OSGIN2,CA4,CBLN1,CLDN10,CCNT1,CIART,SOCS6,JAM2,SULT4A1,CNTFR,BAG4,FEZ2,SCRN1,IP6K1,JAKMIP2,FBXL5,EXOG,TSPAN5,PLEKHA1,C8orf37,EN2,PIPOX,VPS26C,REEP2,ST3GAL6,POLR1B,PRELID3A,CELF1,PHYHIPL,GBX2,C1QL1,GLDC,ZNF638,RNF165,KAT7,SOX21,UBE2QL1,C1orf94,ELOVL5,ZDHHC15,ICA1,NKD1,HES5,IPO5,AQP11,POC1B,SCG3,CAMKV,ANLN,ELOVL2,CASTOR1,RAD17,DPF2,SLC25A36,RIC8B,RPRD1A,TMEM206,MCMBP,WLS,SCP2,TNFRSF19,SUPT20H,PPP4R3A,PKNOX2,SOX2,SPATA7,SPART,LHPP,GANAB,TAC1,TAF6,WWC1,TBL1X,WSCD1,MTMR14,TRH,CLEC2L,FAM181B,CLDND1,PDSS2,ACTR3B" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k2_100 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.44E-02 1.00E+00 4.37E-02 3.98E-01 13 42 "PCDH19,HAPLN1,EMX2,EN2,GAP43,LIX1,EML5,PTPRZ1,RET,NUDT11,NUDT10,BEX4,VSNL1" Coexpression Atlas DevelopingKidney_e15.5_Endothelial cells_emap-29977_k1_200 DevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.44E-02 1.00E+00 4.37E-02 3.98E-01 13 42 "CD38,LY86,CSF1R,CX3CR1,F8,FYB1,LYVE1,NCKAP1L,MSR1,PTPRB,SGK1,ARHGAP9,TEK" Coexpression Atlas GSM605766_500 "alpha beta T cells, T.4FP3-.Sp, 4+ 8- GFP- 44lo, Spleen, avg-3" "Immgen.org, GSE15907" 1.45E-02 1.00E+00 4.38E-02 3.99E-01 76 364 "ACTN1,NDRG3,NDRG2,ADD1,ADD3,AXIN2,ESYT2,PITPNM2,USP28,MADD,ATP1B3,GPR146,FOXK1,ARHGEF1,LRIG1,IPCEF1,SIPA1L1,RIPOR2,TOX,GUCD1,KBTBD11,DLG4,CDON,ATN1,RASGRP1,RASGRP2,MEX3B,NSG2,SARAF,FYB1,FYN,B4GALNT1,RAPGEF6,GGT5,RAPGEF4,BACH2,ZDHHC15,IL6R,IL6ST,ITPKB,L1CAM,SESN3,PDE3B,PDE4D,TMIE,RETREG1,SLC25A23,PACSIN1,SH3KBP1,PPP3CC,PRKCZ,SYTL2,SIDT1,CASTOR1,CEP97,RAVER2,SATB1,SELL,GALNT10,FAM102A,ST6GAL1,ST8SIA1,DZIP1,TET1,TNIK,KIF21B,KIF1B,TCF7,TGFBR3,LRRC8A,RGMB,TRIO,RUNDC3B,SSBP2,SLAIN1,KLHDC1" Coexpression Atlas gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_100 dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_100 Gudmap Mouse ST 1.0 1.45E-02 1.00E+00 4.41E-02 4.01E-01 5 10 "GNG3,TAGLN3,SLC10A4,SST,UCHL1" Coexpression Atlas GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eSC_Subtype_eSCa_Top_200_Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eSC_Subtype_eSCa_Top_200_Genes GSE76381_ESMoleculeCountsPMLog2 1.45E-02 1.00E+00 4.41E-02 4.01E-01 68 321 "ACTN1,MTA3,SEMA6A,ALCAM,ASPH,ATP1A2,ADAM23,CDH2,NUMBL,FOXN3,CHN1,PLEKHB1,CLU,LRIG1,DZIP3,SCRN1,RABGAP1L,DMD,AASS,MRNIP,ADGRV1,FGF13,FGFR1,APOPT1,WASF3,FERMT2,LPAR4,EML4,SOX21,PSIP1,ARHGAP19,ZIC5,LIX1,IPO5,LMO1,MARK3,MEST,SESN3,DDX25,NNAT,NME4,NUMA1,PRTG,PRKAB2,MAPK10,PTPN13,GTDC1,ROBO1,LGR4,SALL1,SCG5,SEPHS1,SOX2,SOX11,TCEA1,TCF7L2,SLC44A1,R3HDM1,TNNT1,RBFOX2,TPM1,ZMYND8,SSBP2,CADM1,VSNL1,ZIC2,ZIC3,FZD3" Coexpression Atlas gudmap_developingGonad_P2_testes_1000_k5 DevelopingGonad_P2_testes_emap-30171_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.46E-02 1.00E+00 4.42E-02 4.03E-01 15 51 "LTBP4,DDX3Y,BACH1,CP,EDNRA,LRRC17,CSDC2,LPAR4,LAMA2,CHIC1,NFIA,NFIX,HHIP,NR2C2,ZBTB16" Coexpression Atlas gudmap_developingKidney_e15.5_Podocyte cells_100 DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_100 Gudmap Mouse MOE430.2 1.48E-02 1.00E+00 4.46E-02 4.07E-01 21 79 "CD38,CNTN1,COL9A1,CDHR1,ST3GAL6,DACH2,FYB1,IGSF5,NEGR1,KCNC2,TM6SF1,MSR1,CLDN11,OXTR,PTPRO,PTX3,PRR5L,SALL1,DDN,TLR4,SYNPO2" Coexpression Atlas Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K5 FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#5 FaceBase_RNAseq 1.48E-02 1.00E+00 4.48E-02 4.08E-01 47 210 "ADCY8,ALCAM,CA4,FOXN3,HAPLN1,CSF1,LRRC3B,HDAC9,CEND1,FGF11,FGFR1,SYT3,JPH4,CSDC2,CECR2,LINGO1,GUCY1A1,HMGCL,TCEAL6,CDH20,GATD1,KHK,MATN2,CD200,CCDC80,PRTG,PENK,ZFYVE21,PLEC,PMP22,IRX1,NKAIN4,PTPRE,TSPY26P,C12orf49,KIAA0895L,EMID1,FOXRED2,SALL1,SLC4A3,PALLD,SOX10,ADAMTS17,FLRT1,ZIC2,CA10,PIANP" Coexpression Atlas gudmap_developingGonad_e11.5_testes and mesonephros_200 DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.50E-02 1.00E+00 4.52E-02 4.12E-01 41 179 "ACLY,ARID1A,ADD1,BACH1,BTRC,CALM1,RBM39,RNF14,DAPK3,DBI,DBN1,DNM1L,EPB41L2,TUBB3,FGFR1,DPYSL4,GAP43,STMN2,GRB10,INSM1,TUBB2B,KLC1,MAPT,NASP,NEFM,NNAT,GNG2,RC3H2,ZFHX4,MEG3,ARX,SMARCA4,SNRPN,SON,SOX2,RBM26,SYT11,PUM2,PCBP4,RTN4,VANGL2" Coexpression Atlas gudmap_kidney_P3_CapMes_Crym_k4_200 kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.51E-02 1.00E+00 4.56E-02 4.16E-01 18 65 "VAT1L,CACNA1G,TENM4,GSDME,IGSF5,CECR2,FAM107A,TM6SF1,NCAM1,NPY,ROBO1,GLDN,CNKSR2,TACR1,CUX2,HEY1,CADM1,SLC38A1" Coexpression Atlas gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k5 DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.51E-02 1.00E+00 4.56E-02 4.16E-01 18 65 "SYT13,INSYN2B,CH25H,NTM,SGIP1,GABRB1,GFRA2,GNG4,WIF1,PRRX1,PRR5L,SALL1,SLC15A2,EPB41L3,TAC1,SATB2,WNT7A,KCNAB1" Coexpression Atlas gudmap_RNAseq_e15.5_Mesangium_2500_K3 gudmap_RNAseq_e15.5_Mesangium_2500_K3 Gudmap RNAseq 1.51E-02 1.00E+00 4.56E-02 4.16E-01 54 247 "ABAT,C1QTNF1,PI16,CD81,DLGAP1,NRXN3,MICAL2,CST3,SDC3,ACY3,ABCC9,HEYL,RASGRP2,RCSD1,RASL12,MRVI1,FCGRT,SORBS1,TPPP3,GGT5,NTNG2,LOXL3,FERMT2,GRM7,GUCY1A1,GUCY1B1,IL6ST,KCND3,TTYH2,MITF,MMP17,CCDC80,NTRK2,PDE1A,PDE3A,PDGFRA,PLCB2,FXYD1,PYGM,FAM184A,RGS4,EMID1,PEAR1,DOCK10,SLC8A1,ZCCHC24,ITPRID2,RGL1,PDLIM2,TNS2,GALNT17,ENHO,IL34,TMEFF2" Coexpression Atlas gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_500 dev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.55E-02 1.00E+00 4.66E-02 4.25E-01 85 414 "GRAMD1B,ADORA2A,HECW2,ADGRF5,SPARCL1,SEMA6A,SEMA7A,MAP4K3,APBB2,SHROOM2,DDX3Y,DOCK11,NRP2,ARHGEF7,C1QC,CBLN1,LDB2,FMNL3,SCARB1,CD38,ABCG2,CRMP1,HAPLN1,PPP1R16B,DOCK4,TOX,RASSF2,GIT2,ELMO1,EBF1,EDNRB,PLEKHA1,CALCRL,RASGRP2,FAM198B,CORO2B,DLC1,FLT1,PDLIM5,FYB1,FYN,GAP43,PCDH17,GGTA1P,GPM6A,LPAR4,RAPGEF4,GRIA2,MAP4K5,ICA1,ITPKB,KIT,LMO2,TM6SF1,MEF2C,PAK3,PDE2A,SPATA6,SNRK,MDGA2,PTPRB,TMEM255A,C1orf54,ROBO1,SEMA6D,RASA3,PREX2,LIMCH1,UNC5B,PEG10,THSD1,KLHL4,TCF4,TEK,HHIP,TIE1,HEY1,TJP1,DCBLD1,RFTN2,VSNL1,WIPF1,ZNF711,NAV3,FAM13C" Coexpression Atlas gudmap_developingKidney_e13.5_podocyte cells_1000_k5 DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#5_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.56E-02 1.00E+00 4.69E-02 4.27E-01 38 164 "ADGRF5,ARRB1,NRP2,CA8,CD38,LY86,CX3CR1,ELMO1,FAM107B,CCDC3,DNM2,ABCC9,EPHB1,FLT1,FYB1,GAP43,PCDH17,GGTA1P,NCKAP1L,IRF8,IGF1,TM6SF1,MSR1,NCF2,NRCAM,GNG2,PTPRB,LIMCH1,SAMSN1,THSD1,TAL1,KLHL4,TEK,TLR4,NPL,TRPC3,WIPF1,RGS7BP" Coexpression Atlas gudmap_developingGonad_e11.5_ovary + mesonephros_k1_1000 DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.57E-02 1.00E+00 4.74E-02 4.32E-01 37 159 "RNF182,FUBP1,CALB1,CDH2,CDH10,CHGB,SOCS6,COL9A1,HAPLN1,DCT,ZNF804A,ALKBH8,EDIL3,EMX2,CHST15,MEX3B,DACH2,CBX1,FAM19A2,MEIS2,PRTG,GPR85,PTX3,ROBO1,ROBO2,CSRNP3,SLC1A3,SPHKAP,ZKSCAN3,RBM26,RGL1,SYPL1,KLHL4,ASXL3,TPM1,STXBP4,SMARCAD1" Coexpression Atlas gudmap_developingGonad_e18.5_testes_200_k1 DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#1_top-relative-expression-ranked_200 Gudmap Mouse MOE430.2 1.58E-02 1.00E+00 4.75E-02 4.33E-01 16 56 "DDR1,CBLN1,CLU,DTNA,EDNRA,EPB41L2,GPM6B,GPR37,PAK3,PDGFRA,MEG3,ARX,SPP1,ACSBG1,HHIP,TST" Coexpression Atlas Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K3 FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#3 FaceBase_RNAseq 1.61E-02 1.00E+00 4.83E-02 4.40E-01 14 47 "ATP1A3,KCNAB3,SEZ6,DLL3,ABLIM2,ARPP21,GLRB,IGSF1,CLEC9A,DIRAS2,STRC,C11orf87,ACSBG1,DNAH10" Coexpression Atlas gudmap_developingKidney_e12.5_renal vesicle_500_k4 DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse MOE430.2 1.61E-02 1.00E+00 4.83E-02 4.40E-01 14 47 "BMP7,CALB1,CRLF1,DUSP9,EMX2,SPSB4,RASL10A,MFSD2A,KIF5C,VWA2,LAMA1,GAL3ST4,PRR5L,SCN8A" Coexpression Atlas Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K3 FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3 FaceBase_RNAseq 1.61E-02 1.00E+00 4.83E-02 4.40E-01 61 285 "AXIN2,DOCK11,TTLL9,CA4,MAP7,CBLN1,FAM19A5,CTH,GREB1,SMG7,CHRDL1,ST8SIA3,LPAR6,PLEKHA1,PIPOX,CD320,NOP56,ZCCHC17,GPR153,GART,LPAR4,CECR2,HSP90AA1,NKD1,SLC35G1,CDH20,IPO5,AQP11,PRTG,PFKP,PKM,PLTP,MAGEL2,IRX1,GDPD2,PTPN13,RPL15,SALL1,TNFRSF19,NUBPL,PKNOX2,SLC20A2,SNRPN,DOK5,NMNAT2,BEX1,PBLD,KANK1,AJAP1,MTCL1,WWC1,WASHC4,BEX4,FLRT1,FAM181B,VSNL1,ZIC2,ZBTB16,CA10,NAV2,AAAS" Coexpression Atlas GSM605756_500 "alpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2" "Immgen.org, GSE15907" 1.62E-02 1.00E+00 4.86E-02 4.43E-01 69 328 "ACTN1,NDRG3,ESYT2,ARHGAP20,PITPNM2,DGKZ,SFMBT2,SYNJ2,CAMK2D,ARHGEF1,LRIG1,IPCEF1,PPP1R16B,TOX,KBTBD11,CDON,RASGRP1,EGR3,KIAA1109,NSG2,FYB1,FYN,B4GALNT1,RAPGEF6,KDM2B,RAPGEF4,BACH2,ZDHHC15,AGFG1,IL6R,IL6ST,TUBB2B,ITPKB,JAK1,CD200,SESN3,NEFH,ZNF827,PCSK1,PDE3B,PDE4D,PENK,PACSIN1,SH3KBP1,PPM1B,PPP3CC,PRKCZ,SYTL2,SIDT1,CASTOR1,CEP97,RGS10,SATB1,SEC14L1,SELL,GALNT10,FAM102A,ST8SIA1,DZIP1,TET1,TNIK,TCF7,AHCYL2,TGFBR3,TRIO,RUNDC3B,TTC3,PMEPA1,SPATA13" Coexpression Atlas facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0 facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0 Gudmap RNAseq 1.63E-02 1.00E+00 4.89E-02 4.45E-01 204 1082 "PLEKHH1,KIAA1211,KLHL13,HACE1,KIAA1324,PDZD4,AMPH,LRCH2,MYH7B,EPB41L5,VAT1L,BCAS1,SHTN1,TMEFF1,ARHGDIG,CAPRIN2,ATM,CADM3,KIF1A,BARD1,BCHE,ZNF599,PROM1,OSGIN2,WASF1,MYRF,CA12,THSD7A,PTBP2,BRSK2,MAP7,SHISA7,MTMR7,CDH2,LRWD1,CACNA2D2,CLCN3,FAM19A5,C4orf33,CNTFR,SLC4A7,BAG4,NECTIN3,SLC35F1,FAM171B,CRMP1,CNTNAP2,FAM169A,CTH,GREB1,CTNND2,TMEM170A,TOMM20,AIF1L,DMD,E2F5,SEZ6L2,TSPAN5,EFNA2,LPAR6,ELAVL2,PLEKHA1,ENO2,RTN3,CEND1,EXTL2,REEP2,TBC1D16,CEP78,SPSB4,FGF13,FHL1,ZMYND15,NOP56,SYT3,CINP,FAM49B,PRELID3A,FUT9,PHYHIPL,GART,RUNDC3A,GLDC,DBF4,TOX3,CBX1,GNG3,GPD2,GPR19,LPAR4,CECR2,STMN2,GRIA4,GRIK2,RNF165,PSIP1,FRMD5,HLF,CFAP126,HSF2,HSP90AA1,LRRCC1,LIX1,LRRTM3,SLC35G1,KCNK1,IPO5,KTN1,CAMK2N2,LMO1,MAOB,MAT2A,AQP11,MEST,MIA2,MSI1,MYCN,NAP1L1,NASP,RCOR2,NOVA2,PAK3,PDE3B,PDE1B,FAM98B,OLA1,SNX10,PKM,PSAT1,POLR2F,FSD1,PPP1R1A,PKIA,PRKCB,MAPK4,RELN,GDPD2,ELOVL2,SPDL1,ZIK1,PTPN13,EML5,PTPRZ1,NKAIN1,CEP97,CCDC40,FAM184A,FIGN,NUDT11,RPL15,RPL38,ACER3,RTN1,SALL1,MAPK12,FAM19A1,ZFP2,ASRGL1,HSPA4L,SCG5,KIF21A,PPM1E,FHOD3,CCDC92,ZNF365,PPP4R3A,PKNOX2,EFHD1,KDM4B,SOX11,BEX1,PBLD,ZC4H2,SYT11,MTCL1,WWC1,CUX2,C18orf54,ITGB3BP,AKTIP,RELL2,ACTR6,BEX4,RGMB,PRMT8,CADM1,UBE3A,SLAIN1,NSD2,XPO1,KCNT2,ZFP41,ZBTB16,TMEM237,SMARCAD1,SLC38A1,RGMA,STOX2,WNK3,AMN1,FZD3,PHTF2,NETO2,SPATA13" Coexpression Atlas gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_500 dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500 Gudmap Mouse ST 1.0 1.64E-02 1.00E+00 4.93E-02 4.50E-01 31 129 "TKTL1,HFM1,ATM,CCDC181,LONRF2,C4orf33,DZIP3,EDRF1,CASP8AP2,DUSP9,KIAA1109,EFCAB2,PHYHIPL,MAP7D2,ADAM22,MYO9A,NEK1,PRTG,PDE3B,EML5,ZCWPW1,ACER3,SH3BGR,CNKSR2,GKAP1,VPS13A,DMXL2,TEX15,RUNDC3B,TRPC1,UGT8" Coexpression Atlas gudmap_kidney_e10.5_UretericTip_HoxB7_k3_1000 kidney_e10.5_UretericTip_HoxB7_k-means-cluster#3_top-relative-expression-ranked_1000 Gudmap Mouse MOE430.2 1.65E-02 1.00E+00 4.93E-02 4.50E-01 50 227 "KCNH8,PCDH19,LCORL,NAE1,CRLF1,B4GALT6,SLIT2,TMEM59L,HAPLN1,FAM169A,CTNND2,TOX,G3BP2,DUSP9,E2F5,PLEKHA1,EMX2,EN2,FDFT1,GAP43,MAP7D2,KCNMB4,GNG3,GRIK2,HMGB1,LIX1,KIT,KITLG,TCEAL5,FAT3,EML5,PTPRZ1,TMEM255A,RADX,RET,MORC4,NUDT11,TRAPPC13,SNRPN,BEX1,SYT11,NUDT10,TCF7,ITGB3BP,BEX4,STXBP4,UCHL1,VSNL1,CAMK1G,SOCS4" Coexpression Atlas BM Top 100 - skeletal muscle BM Top 100 - skeletal muscle Body Map 1.65E-02 1.00E+00 4.94E-02 4.50E-01 20 75 "ACTN2,MYOM1,MYOM2,PDE4DIP,DUSP27,FHL1,PDLIM5,MYOZ2,MYBPC1,MYH7,MYL3,PGAM2,PKIA,PYGM,RYR1,SUPT20H,TPM1,TPM2,TPM3,SYNPO2" Computational M15730 MODULE_11 Genes in the cancer module 11. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.99E-70 5.85E-67 5.85E-67 4.28E-66 292 540 "SERPINA3,ABAT,MTUS1,AGT,ALCAM,SRPX,AMPH,BIN1,AMT,ANK3,APBA2,APBB1,APLP1,FAM131A,APOC1,BCAS1,LGR5,AQP4,ARHGDIG,PDE8B,ALDH4A1,ATP2B1,ATP2B2,ALDH7A1,MTMR9,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,BSN,MYRF,BAIAP3,CFAP410,CA4,CA12,CACNA1A,CALB1,CALB2,HAP1,CAPN3,RHBDL1,MAP7,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,NEURL1,CDH2,DCLK1,LARGE1,CACNA2D2,CHGA,CHGB,CHN2,PLEKHB1,SLIT2,LHX2,NRXN1,STOML1,FADS2,SULT4A1,CABP1,COL9A2,COL9A3,NRG2,CRMP1,CLIP3,CRYM,TENM4,FEZ1,PLCH2,VCAN,NCAN,CNTNAP2,ARHGEF4,RIMS2,PPP6R2,ST18,CX3CR1,GPRASP1,SNPH,RASSF2,RIMS3,PHYHIP,DBN1,ELMO1,MAGI2,SNAP91,PARD6A,SV2B,SV2A,TMCC2,ARNT2,DLG4,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,EEF1A2,EFNA2,EFNB3,CELSR3,EGR3,ELAVL2,ELAVL4,ENO2,RCAN2,DMTN,NCALD,EFS,APC2,F3,FABP7,CACNG3,PTK2B,CHST15,OLFM1,ACTL6B,FGFR1,FGFR3,FOXG1,DPYSL4,TACC2,TRIM16,RASL10A,KHDRBS3,CSPG5,TBR1,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GAD2,GALC,GAP43,WASF3,GATM,TUBGCP4,AHDC1,GFAP,GJB1,RUNDC3A,RND1,GLRB,GNAO1,GNG4,GPM6A,STMN2,GRIA2,GRIK5,GRIN1,KIF3A,FAM107A,GUCY1B1,WIF1,HLF,HPR,INPP1,ITGA7,ITPKA,KCNJ4,KCNK1,KIF5C,L1CAM,STMN1,LMO2,MAOB,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,CD200,TAGLN3,NAP1L3,NCAM1,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NRGN,NTRK2,OMG,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE2A,PDE4B,PDGFRA,ENPP2,PENK,SERPINI1,PKD1,FXYD1,PLP1,PLXNB1,SCHIP1,PPP1R1A,PRKACB,PKIA,PRKCB,PRKCZ,MAPK10,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,PTPRZ1,QDPR,REV3L,RGS4,RGS7,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SGK1,SCG5,SH3BGR,SH3GL3,NTNG1,ST6GAL1,ABLIM3,SLC1A3,SLC1A6,RPH3A,BTBD3,EPN2,FAM214B,SLIT1,SMARCD3,SNAP25,SNCB,KIF21B,SOX10,SPP1,PEG10,KIF1B,TSPYL2,LMO3,COLGALT2,SST,SSTR2,EPB41L3,MAPK8IP3,STX1A,MLC1,ABCC8,PLCB1,ARC,SYT1,SYT5,ACSL6,TCF7,TRIM2,WDR7,SYNE1,CDH22,THRA,KAT6B,TRO,TRPM2,CADM1,PITPNB,VGF,VSNL1,ZIC2,TRIM9,SPHK2,ZBTB16,GDPD5,SCG2,SLC17A7,PCBP4" Computational M12065 MODULE_66 Genes in the cancer module 66. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.31E-65 1.10E-62 5.48E-63 4.01E-62 290 552 "SERPINA3,ABAT,ASIC1,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,ANK3,APBA2,APBB1,APLP1,FAM131A,APOC1,BCAS1,LGR5,AQP4,ARHGDIG,PDE8B,DDX3Y,ALDH4A1,ATP2B1,ATP2B2,ALDH7A1,MTMR9,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,CAPN3,RHBDL1,MAP7,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,NEURL1,CDH2,DCLK1,CDH18,LARGE1,CACNA2D2,CHGA,CHGB,CHN2,PLEKHB1,LHX2,NRXN1,STOML1,FADS2,SULT4A1,CABP1,COL9A2,COL9A3,NRG2,CRMP1,CLIP3,CRYM,TENM4,FEZ1,PLCH2,VCAN,NCAN,CNTNAP2,ARHGEF4,RIMS2,ST18,CX3CR1,GPRASP1,SNPH,RASSF2,RIMS3,PHYHIP,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,MAGI2,SNAP91,PARD6A,SV2B,SV2A,TMCC2,ARNT2,DLG4,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,EEF1A2,EFNA2,EFNB3,CELSR3,ELAVL2,ELAVL4,ENO2,RCAN2,NCALD,EFS,APC2,F3,FABP7,CACNG3,PTK2B,CHST15,OLFM1,ACTL6B,FGFR1,FGFR3,FOXG1,FOLR2,DPYSL4,TACC2,RASL10A,KHDRBS3,CSPG5,TBR1,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GAP43,WASF3,GATM,TUBGCP4,AHDC1,GFAP,GJB1,RUNDC3A,RND1,GLRB,GNAO1,GNG4,GPM6A,STMN2,GRIA2,GRIK1,GRIK5,GRIN1,KIF3A,FAM107A,GUCY1B1,WIF1,HPR,INPP1,INSM1,ITGA7,ITPKA,KCNJ4,KCNK1,KIF5C,L1CAM,LAMA2,STMN1,LMO2,MAOB,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NAP1L3,NCAM1,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NRGN,NTRK2,OMG,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE2A,PDE4B,PDGFRA,ENPP2,PENK,PFKFB4,SERPINI1,PKD1,PLCB2,FXYD1,PLP1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,PRKCZ,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,PTPRZ1,QDPR,RGS4,RGS7,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SCG5,SH3BGR,SH3GL3,ABLIM3,SLC1A3,SLC1A6,RPH3A,BTBD3,EPN2,FAM214B,SLIT1,SMARCD3,SNAP25,SNCB,KIF21B,SOX10,SPP1,PEG10,TSPYL2,SST,SSTR2,EPB41L3,MAPK8IP3,STX1A,STXBP1,MLC1,ABCC8,PLCB1,ARC,SYT1,SYT5,ACSL6,TRIM2,WDR7,SYNE1,TF,THBS4,CDH22,THRA,KAT6B,TRO,TRPM2,CADM1,UCHL1,PITPNB,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,ZBTB16,SCG2,SLC17A7,PCBP4" Computational M19344 MODULE_100 Genes in the cancer module 100. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.47E-64 3.74E-61 1.25E-61 9.11E-61 285 544 "SERPINA3,ABAT,ASIC1,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,ANK3,APBA2,APBB1,APLP1,FAM131A,APOC1,BCAS1,LGR5,AQP4,ARHGDIG,PDE8B,DDX3Y,ALDH4A1,ATP2B2,ALDH7A1,MTMR9,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,RHBDL1,MAP7,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,NEURL1,CDH2,DCLK1,CDH18,LARGE1,CACNA2D2,CHGA,CHGB,CHN2,PLEKHB1,LHX2,NRXN1,STOML1,FADS2,SULT4A1,CABP1,COL9A2,COL9A3,NRG2,CRMP1,CLIP3,CRYM,TENM4,FEZ1,PLCH2,VCAN,NCAN,CNTNAP2,ARHGEF4,RIMS2,ST18,CX3CR1,GPRASP1,SNPH,RASSF2,RIMS3,PHYHIP,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,MAGI2,SNAP91,PARD6A,SV2B,SV2A,TMCC2,ARNT2,DLG4,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,EEF1A2,EFNA2,EFNB3,CELSR3,ELAVL2,ELAVL4,ENO2,RCAN2,NCALD,EFS,APC2,F3,FABP7,CACNG3,PTK2B,CHST15,OLFM1,ACTL6B,FGFR1,FGFR3,FOXG1,FOLR2,DPYSL4,TACC2,RASL10A,KHDRBS3,CSPG5,TBR1,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GAP43,WASF3,GATM,TUBGCP4,AHDC1,GJB1,RUNDC3A,RND1,GLRB,GNAO1,GNG4,GPM6A,STMN2,GRIA2,GRIK1,GRIK5,GRIN1,KIF3A,FAM107A,GUCY1B1,WIF1,HPR,INPP1,INSM1,ITGA7,ITPKA,KCNJ4,KCNK1,KIF5C,L1CAM,LAMA2,STMN1,LMO2,MAOB,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NAP1L3,NCAM1,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NRGN,NTRK2,OMG,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE2A,PDE4B,PDGFRA,ENPP2,PENK,PFKFB4,SERPINI1,PKD1,FXYD1,PLP1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,PRKCZ,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,PTPRZ1,QDPR,RGS4,RGS7,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SCG5,SH3BGR,SH3GL3,ABLIM3,SLC1A3,SLC1A6,RPH3A,BTBD3,EPN2,FAM214B,SLIT1,SMARCD3,SNAP25,SNCB,KIF21B,SOX10,SPP1,PEG10,TSPYL2,SST,SSTR2,EPB41L3,STX1A,STXBP1,MLC1,ABCC8,PLCB1,ARC,SYT1,SYT5,ACSL6,TRIM2,WDR7,SYNE1,TF,THBS4,CDH22,THRA,KAT6B,TRO,TRPM2,CADM1,UCHL1,PITPNB,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,ZBTB16,SCG2,SLC17A7,PCBP4" Computational M2519 MODULE_137 CNS genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.07E-63 5.08E-60 1.27E-60 9.29E-60 284 546 "SERPINA3,ABAT,ASIC1,KDM5D,MTUS1,AGT,SPARCL1,ALCAM,SRPX,AMPH,BIN1,AMT,ANK3,APBA2,APBB1,APLP1,FAM131A,APOC1,BCAS1,LGR5,AQP4,ARHGDIG,ASCL1,DDX3Y,ALDH4A1,ATP2B2,ALDH7A1,MTMR9,ATP6V1G2,ATP6V0A1,ST3GAL5,SGCE,MYRF,BAIAP3,CFAP410,CA12,CACNA1A,CALB1,CALB2,RHBDL1,MAP7,RUNX1T1,CBLN1,CBR1,CLDN10,KYAT1,CCK,LDB2,NEURL1,CDH2,DCLK1,LARGE1,CACNA2D2,CHGA,CHGB,CHN2,PLEKHB1,LHX2,NRXN1,STOML1,FADS2,SULT4A1,CABP1,COL9A2,COL9A3,NRG2,CRMP1,CLIP3,CRYM,TENM4,FEZ1,PLCH2,VCAN,NCAN,CNTNAP2,ARHGEF4,RIMS2,ST18,CX3CR1,GPRASP1,SNPH,RASSF2,RIMS3,PHYHIP,SCRN1,SPOCK2,DBN1,ARMCX2,ELMO1,MAGI2,SNAP91,PARD6A,SV2B,SV2A,TMCC2,ARNT2,DLG4,DNM1,DYNC1I1,DPP6,DTNB,ABCC5,EDNRB,EEF1A2,EFNA2,EFNB3,CELSR3,ELAVL2,ELAVL4,ENO2,RCAN2,NCALD,EFS,APC2,F3,FABP7,CACNG3,PTK2B,CHST15,OLFM1,ACTL6B,FGFR1,FGFR3,FOXG1,FOLR2,DPYSL4,TACC2,RASL10A,KHDRBS3,CSPG5,TBR1,GABBR1,CHL1,GABRB3,GABRG2,GAD1,GAP43,WASF3,GATM,TUBGCP4,AHDC1,GJB1,RUNDC3A,RND1,GLRB,GNAO1,GNG4,GPM6A,STMN2,GRIA2,GRIK1,GRIK5,GRIN1,KIF3A,FAM107A,GUCY1B1,WIF1,HPR,INPP1,INSM1,ITGA7,ITPKA,KCNJ4,KCNK1,KIF5C,L1CAM,LAMA2,STMN1,LMO2,MAOB,MAP2,MAPT,MBP,MEF2C,MEIS2,SCAMP5,TAGLN3,NAP1L3,NCAM1,NEFM,NNAT,NPY,NOVA1,NOVA2,NPTX1,NRGN,NTRK2,OMG,PALM,PAX6,PCDH9,PCSK1,CDK18,PDE2A,PDE4B,PDGFRA,ENPP2,PENK,PFKFB4,SERPINI1,PKD1,FXYD1,PLP1,PLXNB1,SCHIP1,PPP3CA,PRKACB,PKIA,PRKCB,PRKCZ,MAPK10,RELN,KLK6,PSD,SNRK,PTN,PTPRD,PTPRN,PTPRN2,PTPRO,QDPR,RGS4,RGS7,KCTD17,RNASE1,EXD2,RTN1,RYR3,S100B,SCN2B,SCG5,SH3BGR,SH3GL3,ABLIM3,SLC1A3,SLC1A6,RPH3A,BTBD3,EPN2,FAM214B,SLIT1,SMARCD3,SNAP25,SNCB,KIF21B,SOX10,SPP1,PEG10,TSPYL2,SST,SSTR2,EPB41L3,STX1A,STXBP1,MLC1,ABCC8,PLCB1,ARC,SYT1,SYT5,ACSL6,TRIM2,WDR7,SYNE1,TF,THBS4,CDH22,THRA,KAT6B,TRO,TRPM2,CADM1,UCHL1,PITPNB,VGF,VSNL1,ZIC1,ZIC2,TRIM9,SPHK2,ZBTB16,SCG2,SLC17A7,PCBP4" Computational M3373 GNF2_DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.42E-26 6.21E-23 1.24E-23 9.08E-23 57 73 "SLC12A5,AMPH,ATP2B2,ATP6V1G2,BSN,CAMK2A,CAMK2B,CHN1,SULT4A1,PREPL,CLIP3,CTNND2,PHYHIP,SNAP91,SV2B,SV2A,ARNT2,DNM1,EPB41L1,RCAN2,NRN1,CORO2B,OLFM1,PNMA2,GABRA1,GAP43,RUNDC3A,GNG3,KCNQ2,KIF5C,MAPT,TAGLN3,FXYD7,NAP1L2,NAP1L3,DIRAS2,RAB3A,RGS7,SH3GL2,ZNF365,SLC1A3,RPH3A,SNAP25,SNCB,FAIM2,NMNAT2,STXBP1,SYT11,ARHGEF9,SYN1,SYT1,CAMTA1,RALYL,PSD3,VSNL1,NDRG4,SLC17A7" Computational M15252 GCM_MAPK10 Neighborhood of MAPK10 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.26E-20 1.06E-17 1.76E-18 1.29E-17 56 82 "NDRG2,APLP1,PDXK,ATP1A2,BBS2,NIPA1,CAMK2A,CAMK2G,DCLK1,PLEKHB1,FAM19A5,FAM171B,PREPL,CLIP3,FEZ1,CTNND2,NRSN1,DNAJC6,SNAP91,ARNT2,DTNA,PLEKHA1,FGF1,GABBR1,AHCYL1,GPM6B,FAM107A,KCNJ10,KCNQ3,TTYH2,MBP,IL17D,SCAMP5,TMOD2,SERPINI1,PLP1,MAPK10,SCN2B,CNKSR2,SLC1A3,BTBD3,EFHD1,FAM219A,NMNAT2,NFASC,LMO3,EPB41L3,SYT11,TACC1,DDHD2,FBXW11,SIK3,SLAIN1,VSNL1,CLDND1,ANKS1B" Computational M8546 GNF2_MAPT Neighborhood of MAPT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.26E-20 3.57E-17 5.10E-18 3.72E-17 36 41 "ANK2,ADGRB3,NRXN1,CLIP3,SNAP91,SV2B,SV2A,ARNT2,DNM1,DYNC1I1,ELAVL4,PNMA2,GAP43,RUNDC3A,GNAO1,GPM6A,GRIA2,KCNQ2,KIF5C,MAPT,FXYD7,NAP1L3,PALM,DIRAS2,RGS7,RTN1,SH3GL2,SLC1A3,SNCB,SCN3B,KIF1B,STXBP1,SYN1,SYT1,RALYL,PSD3" Computational M18929 MODULE_12 Spinal cord (neuro-development) genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.18E-18 3.50E-15 4.38E-16 3.20E-15 145 360 "SERPINA3,ABAT,MTUS1,AGT,ALCAM,SRPX,BIN1,ANK3,APBA2,APBB1,APLP1,APOC1,BCAS1,AQP4,SLC4A4,ALDH7A1,ATP6V0A1,DST,ST3GAL5,SGCE,MYRF,USP6,INA,CDH2,DCLK1,SLIT2,TJP2,FADS2,CNN3,ARHGEF6,COL9A3,CRMP1,CLIP3,FEZ1,ARHGEF10,VCAN,NCAN,ARHGEF4,CX3CR1,KIAA0513,RASSF2,DBN1,SV2A,ARNT2,DNM1,DNM2,DPP6,ECM2,EDNRB,EEF1A2,ELN,ENO2,EPB41L2,EFS,F3,FABP7,CHST15,FCGRT,FGF1,FGFR1,FGFR3,C1orf61,PDLIM5,TRIM16,GABBR1,GAP43,WASF3,GATM,AHDC1,GFAP,PCDH17,GJB1,FERMT2,GPM6A,STMN2,GRIA2,GRIN1,FAM107A,VSIG4,ITGA7,KIF5C,L1CAM,MAOB,MBP,NCAM1,NEFM,NNAT,NOVA1,SLC11A2,NTRK2,OMG,PALM,PAX6,PCDH9,CDK18,PDE4B,PDGFRA,ENPP2,PENK,SERPINI1,PLEC,FXYD1,PLP1,SCHIP1,KLK6,PTN,PTPN13,PTPRZ1,PTX3,QDPR,RNASE1,RTN1,S100B,SATB1,SCG5,SH3GL3,SLC1A3,SMTN,SNAP25,SOX10,SPP1,PEG10,TSPYL2,LMO3,ATP10B,COLGALT2,SST,EPB41L3,MAPK8IP3,SYT11,MLC1,ZEB1,TRIM2,WDR7,THRA,DAAM2,TNFRSF1B,TPM1,TRO,CADM1,UGT8,VSNL1,ZIC1,ZBTB16,PCBP4" Computational M15601 GNF2_RAB3A Neighborhood of RAB3A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.26E-15 4.40E-12 4.78E-13 3.49E-12 30 37 "SLC12A5,SULT4A1,SNAP91,SV2B,SV2A,ARNT2,DNM1,DPP6,EPB41L1,RCAN2,GABBR1,GAP43,RUNDC3A,GRM3,KCNQ2,KIF5C,TAGLN3,FXYD7,NRCAM,RAB3A,RGS7,SH3GL2,FAIM2,STXBP1,SYT11,ARHGEF9,SYN1,SYT1,RALYL,NDRG4" Computational M10137 GNF2_RTN1 Neighborhood of RTN1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.71E-15 4.78E-12 4.78E-13 3.49E-12 37 52 "ANK2,ASTN1,ADGRB3,CDK5R1,INA,DCLK1,NRXN1,NRXN2,CLIP3,NCAN,CTNND2,FAM131B,DNAJC6,SNAP91,DYNC1I1,TMEM35A,CSPG5,GAD1,GAP43,GNAO1,GPM6A,KCNQ2,KIF5C,MAPT,FXYD6,NAP1L3,RGS7,RTN1,WDR47,SCN3B,MYT1L,NMNAT2,KIF1B,STXBP1,TRIM2,RALYL,STMN4" Computational M17046 GCM_PTK2 Neighborhood of PTK2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.44E-14 6.22E-11 5.66E-12 4.14E-11 70 145 "RALGAPA1,ABHD6,NDRG3,FMNL2,KIDINS220,PKP4,SHTN1,BBS2,MTMR2,NIPA1,BTRC,DIRAS1,CAMK2G,LARGE1,PLEKHB1,CLCN3,FAM19A5,TMEM184B,MAP4K4,PREPL,DZIP3,DNAJC6,ZEB2,ABI2,GOLGA7,PLEKHA1,KIAA1109,STAMBP,NPTN,PHYHIPL,AHCYL1,TJAP1,KIF5C,TTYH2,MGAT3,SESN3,TMOD2,PTK2,OCIAD1,PTPRD,CCDC82,CNKSR2,CCDC92,BTBD3,CCDC88A,USP33,FAM219A,TEX2,ARHGAP26,KIF1B,CLASP2,EPB41L3,MAPK8IP3,DDHD2,FBXW11,DOCK9,TNS2,FRYL,SIK3,GZF1,WBP2,EIF4ENIF1,UBE2H,GORASP1,SLAIN1,CLDND1,ANKS1B,SPIRE1,SNX27,RTN4" Computational M10191 GCM_MAP4K4 Neighborhood of MAP4K4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.39E-12 1.17E-09 9.71E-11 7.10E-10 76 171 "RALGAPA1,ABHD6,FMNL2,KIDINS220,MTUS1,BBS2,MTMR2,BTRC,CALM1,SPAG9,PLEKHB1,CLCN3,FAM19A5,MAP4K4,PREPL,SH2B1,CLIP3,PDE4DIP,DZIP3,PITPNC1,ZEB2,ARNT2,DTNA,SH3GLB1,ABI2,GOLGA7,EPB41L2,APC2,KIAA1109,ANKFY1,NPTN,AHCYL1,GPM6B,TJAP1,IL6ST,IPO5,TTYH2,IL17D,SCAMP5,SESN3,MYO9A,TMOD2,PSAT1,PTK2,OCIAD1,PTPRD,RDX,CCDC92,SIRT2,CCDC88A,FAM219A,PDZD2,TNIK,KIF1B,CLASP2,POGZ,ERBIN,MAPK8IP3,DDHD2,FBXW11,ATMIN,TNS2,FRYL,SIK3,GZF1,LRRC8A,WBP2,EIF4ENIF1,UBE2H,GORASP1,SLAIN1,CLDND1,ANKS1B,SPIRE1,SNX27,RTN4" Computational M13367 GNF2_TM4SF2 Neighborhood of TM4SF2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.87E-12 4.08E-09 3.14E-10 2.29E-09 22 26 "SLC12A5,ATP2B2,BSN,CLIP3,PHYHIP,SNAP91,SV2B,SV2A,DNM1,HPCAL4,RUNDC3A,GNAO1,TAGLN3,NAP1L2,DIRAS2,SH3GL2,SNAP25,FAIM2,NMNAT2,STXBP1,SYN1,RALYL" Computational M10420 MODULE_274 Vesicular transport / synapse genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.23E-12 6.89E-09 4.92E-10 3.60E-09 45 82 "ABAT,ASIC2,DOC2A,AMPH,ANK3,CBLN1,CHRM1,CHRNB2,CPNE6,DLG4,DNM1,GABRA1,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,GLRB,GRIA2,GRIK1,GRIK2,GRIN1,GRM2,GRM3,HTR2A,KCNK3,KCNN1,KCNQ3,KIF5A,NCAM1,NOS1,NOVA1,NPTX1,SCN2B,SLC1A3,SLC1A6,SLC6A7,SLC6A8,SNAP25,SST,SYN1,SYN2,SYT1,SYT5" Computational M3543 GCM_NCAM1 Neighborhood of NCAM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.55E-09 2.14E-06 1.43E-07 1.04E-06 56 128 "RALGAPA1,KIDINS220,ALS2,IGDCC4,MTMR9,MTMR3,BTRC,CALM1,PTBP2,SPAG9,CLCN3,IQCK,CEP170,RABGAP1L,DMTF1,KMT5B,RASA4,DCTN4,ERBB4,CORO2B,UBE2E3,FOXO3,CELF1,PHYHIPL,DENND2A,BRPF3,AHDC1,USP19,KAT7,SMAP1,KIF5C,SESN3,NCAM1,NFYA,NPTX1,BSDC1,CCDC82,PNMA8A,AMER2,PPM1E,KIF1B,CLASP2,USP22,KAT6B,RBFOX2,CADM1,EIF4ENIF1,UBE2H,UBE3A,NSD2,REEP1,TMEM237,SPIRE1,ZFAND5,SYNC,PARP6" Computational M3849 GNF2_AF1Q Neighborhood of AF1Q MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.37E-09 3.66E-06 2.29E-07 1.67E-06 19 25 "ANK2,ASTN1,INA,DCLK1,CLIP3,NCAN,DYNC1I1,CSPG5,GAD1,GAP43,GNAO1,GPM6A,STMN2,KIF5C,PTPRD,RTN1,MYT1L,RALYL,STMN4" Computational M10475 GCM_PTPRD Neighborhood of PTPRD MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.39E-08 2.84E-05 1.67E-06 1.22E-05 31 58 "RALGAPA1,ABHD6,NDRG3,PKP4,NIPA1,BTRC,FAM19A5,MAP4K4,PREPL,ZEB2,ABI2,PLEKHA1,KIAA1109,PHYHIPL,TTYH2,PTK2,PTPRD,ACER3,CCDC88A,FAM219A,KIF1B,CLASP2,FBXW11,DOCK9,FRYL,SIK3,GZF1,UBE2H,SLAIN1,ANKS1B,SPIRE1" Computational M16631 GCM_MAP1B Neighborhood of MAP1B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.41E-08 5.37E-05 2.98E-06 2.18E-05 33 65 "RALGAPA1,KIDINS220,CDC42BPA,BTRC,DIRAS1,CALM1,SPAG9,PREPL,CEP170,RABGAP1L,ABI2,PHYHIPL,CELF3,SMAP1,KIF5C,NCAM1,NPTX1,DUSP26,PTPRD,PNMA8A,AMER2,CCDC92,ELMO2,FAM219A,KIF1B,CLASP2,FBXW11,USP22,SIK3,RBFOX2,EIF4ENIF1,TMEM237,SPIRE1" Computational M10977 MODULE_563 Genes in the cancer module 563. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.31E-08 6.95E-05 3.66E-06 2.67E-05 13 15 "ABAT,CADPS,SYNJ1,BAIAP3,COPB2,SNPH,GABRA2,GAD1,GAD2,SLC1A3,SNAP25,STX1A,SYN1" Computational M19545 GCM_DLG1 Neighborhood of DLG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.02E-07 8.55E-05 4.28E-06 3.13E-05 37 78 "ABHD6,ATP2B2,NIPA1,CAMK2G,PLEKHB1,FAM19A5,MAP4K4,PREPL,GOLGA7,PLEKHA1,KIAA1109,STAMBP,NPTN,IL6ST,KCNJ10,IPO5,MAPK10,PTK2,OCIAD1,CCDC25,CCDC92,BTBD3,FAM219A,EPB41L3,ERBIN,MAPK8IP3,DDHD2,FBXW11,TNS2,FRYL,SIK3,TF,GORASP1,SLAIN1,CLDND1,SH3GLB2,RTN4" Computational M4537 GCM_AQP4 Neighborhood of AQP4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.69E-07 2.25E-04 1.07E-05 7.84E-05 25 45 "TTYH1,NDRG2,FMNL2,AGT,AQP4,PDE8B,SLC4A4,BBS2,QKI,LRIG1,PDE4DIP,ARNT2,DTNA,EPB41L2,ANKFY1,AHCYL1,DNER,GPM6B,TTYH2,IL17D,TMOD2,PSAT1,RDX,TACC1,DAAM2" Computational M5770 MODULE_63 Porins / transporters. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.05E-07 2.55E-04 1.16E-05 8.47E-05 75 211 "ASIC1,KLRC4,ADCYAP1R1,ADRB2,CNTNAP1,SHROOM2,AQP4,AQP6,ASGR1,BMPR1B,CACNG1,CD86,CRLF1,CHRM1,CHRNA4,CNGA3,CNTFR,CSF2RA,CSF3R,CYBB,EPHB1,ERBB2,ERBB4,FCGR1A,FCGR3A,FCGRT,FGFR1,FGFR3,SEMA4D,FOLR2,GABRA2,GABRB3,GABRG2,GFRA1,GFRA2,GHR,GJB1,GPR75,LILRB4,LILRA2,GRIK1,GRIK3,GRIN1,IL6R,IL6ST,ITGAM,KCNA1,KCNA4,KCNA6,KCNH2,KCNJ11,KCNK1,KCNK3,KCNQ3,KIT,LIFR,NTRK2,DDR2,OLR1,P2RX7,PDGFRA,FXYD1,PTPRN,PTPRN2,PTPRO,RYR1,SCN2B,SCN7A,MLC1,TEK,TGFBR3,TIE1,TNFRSF1B,TRPM2,GJC2" Computational M2150 GCM_RAN Neighborhood of RAN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.62E-07 6.38E-04 2.77E-05 2.03E-04 70 197 "RALGAPA1,ABHD6,NDRG3,KIDINS220,GPRASP2,ATP2B2,MTMR3,BTRC,CALM1,SPAG9,LARGE1,CLCN3,FAM19A5,HECTD1,MAP4K4,IQCK,PREPL,SH2B1,CS,PITPNC1,ABI2,GOLGA7,DCTN4,KIAA1109,UBE2E3,FOXO3,JKAMP,STAMBP,ZNF512,PHYHIPL,BRPF3,USP19,PRRC2B,RBPJ,KIF5C,IPO5,MAP6,SESN3,NCAM1,TNPO2,PPM1B,PTK2,OCIAD1,UBR7,KLHL11,CCDC82,PNMA8A,CHD9,CCDC92,SLC8A2,CCDC88A,USP33,FAM219A,KIF1B,CLASP2,POGZ,MAPK8IP3,FBXW11,TNS2,SIK3,GZF1,WBP2,EIF4ENIF1,GORASP1,TMEM237,SPIRE1,ZFAND5,SNX27,RTN4,AAAS" Computational M1706 GCM_SIRT2 Neighborhood of SIRT2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.98E-06 1.66E-03 6.90E-05 5.04E-04 23 43 "MTUS1,PLEKHB1,MAP4K4,PDE4DIP,PITPNC1,GOLGA7,TNK2,MRVI1,ANKFY1,GABBR1,IL6ST,KCNJ10,SCAMP5,MYO9A,SIRT2,FAM219A,MAPK8IP3,DDHD2,FBXW11,TNS2,GORASP1,SNX27,RTN4" Computational M785 MODULE_316 Ion channels. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.69E-06 5.60E-03 2.24E-04 1.64E-03 31 70 "ASIC1,KCNAB2,SHROOM2,AQP4,CACNB4,CACNG1,CHRNA4,CNGA3,GABRA1,GABRA2,GABRA5,GABRB3,GABRG2,GJB1,GRIK1,GRIK2,GRIK3,GRIN1,KCNA1,KCNA6,KCNH2,KCNJ3,KCNJ4,KCNJ11,KCNK1,FXYD7,FXYD1,RYR1,SLC9A5,MLC1,GJC2" Computational M2283 MODULE_41 Genes in the cancer module 41. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.60E-06 7.19E-03 2.77E-04 2.02E-03 159 566 "ASIC2,ARID1A,NDRG2,ADD2,ADRA1D,SEMA7A,APLP1,LGR5,CDK13,ASGR1,N4BP2L1,ATP6V1G2,MYOM1,RGS9,CDK5R2,CALB2,HAP1,CAMK2B,CAPN3,RHBDL1,CBLN1,CD86,ENTPD2,NEURL1,REPS2,MAGI1,CACNA2D2,ASIC3,SLC22A6,PPT2,NRXN1,SULT4A1,AKAP7,NRG2,RIMS2,PPP6R2,FAM131B,ECE2,KIAA0586,PHYHIP,ZBTB24,MYEF2,DLG4,DNAH9,DTNB,EFNA3,FAM13A,ELAVL2,SRPK3,RCAN2,DMTN,NCALD,APC2,ACTL6B,SEMA4D,FLT1,AKAP3,DPYSL4,TACC2,TRIM16,RASL10A,PRELID3A,NSG1,TBR1,GAD2,TUBGCP4,SRCAP,RUNDC3A,CRCP,MSL3,GNG4,GPR17,DIDO1,GRIK2,GRIK5,GSTM5,VSIG4,HPR,HSD17B1,HSF2,HTR2A,KCND3,KCNJ4,KCNN1,KCNQ3,L1CAM,LMO1,MAG,MEF2C,SCAMP5,MID1,MPP2,TAGLN3,CNOT4,PCBP3,OGG1,OPRL1,PAX6,PDE4A,PDGFRA,PFKFB2,PGAM2,PHKG1,PLCB2,JAKMIP1,PLIN1,C19orf57,POU6F1,PPP3CA,PPP3CC,PRPH,PSD,PTPRD,RAD51D,KCTD17,EXD2,ZC3H14,EMID1,SCN2B,NTNG1,SLC1A6,RPH3A,FAM214B,SLC6A7,SLC6A9,SLC6A11,INTS9,SNAP25,KIF21B,SOX10,SPART,COLGALT2,APOM,STXBP1,MLC1,ABCC8,VAMP1,SYT5,ADGRL3,SZT2,THRA,TJP1,PARD3,TNNT1,TNR,SEZ6L,LILRA4,TRPM2,NTSR2,HSPBP1,TUB,VAV2,ZIC2,SLC30A3,DNALI1,CIAPIN1,SLC17A7,KCNAB1,EPM2A" Computational M14588 MODULE_113 Genes in the cancer module 113. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.93E-05 1.62E-02 5.99E-04 4.38E-03 41 107 "ALAD,APLP1,CADPS,ATP2B2,CBLN1,CBS,CHN2,CHRNA4,CLCN4,CRMP1,DLG4,DMD,DPP6,EFNB3,FGFR3,C1orf61,FLT1,RASL10A,TBR1,GAD1,GAP43,GHR,GPM6A,HAS2,KCNB1,KCNN3,MAG,MAP2,NAP1L3,NOVA1,OMG,OPCML,PAH,PDCD2,PIK3CD,PTPRO,RGR,RGS7,SPTB,TIAM1,ZIC1" Computational M14302 MODULE_497 CNS development. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.43E-05 3.71E-02 1.32E-03 9.67E-03 16 29 "KIAA0040,FOXG1,TBR1,GABRA5,GRIK1,NHLH1,NNAT,NPTX1,PAX6,SERPINI1,S100B,SLIT1,SNCA,TAC1,UGT8,ZIC1" Computational M686 GCM_GSTA4 Neighborhood of GSTA4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.67E-05 5.58E-02 1.93E-03 1.41E-02 28 67 "KIDINS220,MTMR3,CALM1,IQCK,PLPPR4,DCTN4,ERBB4,UBE2E3,FOXO3,BRPF3,PRRC2B,MAP6,AFDN,MSI1,NCAM1,TNPO2,KLHL11,ATAT1,AMER2,SLC8A2,POGZ,ASTN2,USP22,RBFOX2,WBP2,NSD2,TMEM237,ZFAND5" Computational M15207 GCM_CALM1 Neighborhood of CALM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.63E-05 6.39E-02 2.10E-03 1.54E-02 40 109 "RALGAPA1,KIDINS220,GPRASP2,BTRC,CALM1,LARGE1,CLCN3,MAP4K4,PREPL,CLIP3,ABI2,APC2,CORO2B,FOXO3,NCKAP1,USP19,KIF5C,MAP6,SCAMP5,SESN3,NCAM1,DUSP26,TNPO2,PNMA8A,CCDC92,SLC8A2,USP33,FAM219A,KIF1B,CLASP2,POGZ,MAPK8IP3,MCF2L,FBXW11,SIK3,WBP2,EIF4ENIF1,SPIRE1,SNX27,RTN4" Computational M1901 MODULE_533 Genes in the cancer module 533. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.00E-05 6.69E-02 2.10E-03 1.54E-02 21 45 "AMPH,USP37,CCNT1,DYNC1I1,DTNB,TUBB4A,AGAP3,TACC2,STMN2,FAM107A,KIF5A,KIF5C,STMN1,MAPT,MID1,MYH7,NCAM1,NELL1,SEPT4,SNAP25,STX1A" Computational M12229 MODULE_381 Genes in the cancer module 381. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.04E-05 6.73E-02 2.10E-03 1.54E-02 9 12 "DOC2A,AMPH,CHGA,PALM,RAB3A,SYN2,SYT1,SYT5,SLC30A3" Computational M19241 MODULE_181 Genes in the cancer module 181. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.51E-05 7.12E-02 2.16E-03 1.58E-02 91 306 "NDRG2,ADRA1D,SEMA7A,ATP6V1G2,RGS9,CDK5R2,CFAP410,CALB2,HAP1,RHBDL1,CBLN1,CCK,CD86,ENTPD2,REPS2,MAGI1,ASIC3,TAOK2,SLC22A6,PPT2,NRXN1,AKAP7,NRG2,RIMS2,PPP6R2,FAM131B,ECE2,KIAA0586,ZBTB24,MYEF2,FAM13A,ELAVL2,SRPK3,NCALD,APC2,ACTL6B,FLT1,AKAP3,TACC2,RASL10A,PRELID3A,NSG1,TBR1,RUNDC3A,CRCP,GNG4,GRIK5,GRM2,HPR,HSD17B1,KCND3,KCNN1,KCNQ3,L1CAM,SCAMP5,MSI1,TAGLN3,NNAT,PDE4A,PGAM2,JAKMIP1,PLIN1,PPP3CA,PSD,PTPRN,RAD51D,KCTD17,EXD2,ZC3H14,EMID1,SCN2B,NTNG1,RPH3A,FAM214B,SNAP25,KIF21B,SOX10,SPART,SSTR2,MLC1,ABCC8,VAMP1,SYT5,ADGRL3,ACSL6,THRA,SEZ6L,LILRA4,TRPM2,SLC17A7,EPM2A" Computational M17233 MODULE_104 Genes in the cancer module 104. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.13E-04 9.46E-02 2.78E-03 2.03E-02 102 353 "ARID1A,NDRG2,ADRA1D,SEMA7A,ATP6V1G2,RGS9,CDK5R2,CFAP410,CALB2,HAP1,RHBDL1,CBLN1,CCK,CD86,ENTPD2,REPS2,MAGI1,ASIC3,TAOK2,SLC22A6,PPT2,NRXN1,AKAP7,NRG2,RIMS2,PPP6R2,FAM131B,ECE2,KIAA0586,ZBTB24,MYEF2,DNAH9,DTNB,FAM13A,ELAVL2,SRPK3,NCALD,APC2,ACTL6B,FLT1,AKAP3,TACC2,RASL10A,PRELID3A,NSG1,TBR1,RUNDC3A,CRCP,GNG4,GPR17,DIDO1,GRIK5,GRM2,HPR,HSD17B1,KCND3,KCNN1,KCNQ3,L1CAM,MSI1,TAGLN3,NNAT,PAX6,PDE4A,PGAM2,JAKMIP1,PLIN1,C19orf57,PPP3CA,PSD,PTPRN,RAD51D,KCTD17,EXD2,ZC3H14,EMID1,SCN2B,NTNG1,RPH3A,FAM214B,INTS9,SNAP25,KIF21B,SOX10,SPART,SSTR2,MLC1,ABCC8,VAMP1,SYT5,ADGRL3,ACSL6,SZT2,THRA,PARD3,TNNT1,SEZ6L,LILRA4,TRPM2,DNALI1,SLC17A7,EPM2A" Computational M1575 MODULE_207 Genes in the cancer module 207. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.44E-04 1.21E-01 3.45E-03 2.52E-02 70 226 "ACTN2,FMNL2,GALNT13,BBOX1,PDE8B,SYT6,ARHGEF25,DLGAP2,CFL2,CLOCK,HINFP,GDA,CNTNAP2,ST18,SPOCK3,SRGAP3,CD99L2,DYNC1I1,SEZ6L2,CDKL3,DNAJC27,FOXG1,CAP2,FOXF2,AKAP3,JPH4,DISC1,FAXC,CYP46A1,CSDC2,LINGO1,AGBL5,KCND1,KIFC3,PAXBP1,MPP2,NTRK3,SNTG1,GDAP1L1,ZNF655,ST8SIA5,FA2H,LRRN3,PRPSAP2,PBRM1,LGI2,HSPA4L,RPH3A,OGDHL,FAIM2,PDZD2,SST,NSFL1C,PHF24,FAM189A1,NSD1,SIK3,TF,KHDC1,ACTR6,DDHD1,ZFP91,RBFOX2,ZKSCAN5,SMARCAD1,PRTFDC1,GAL3ST3,TMEM163,ACTR3B,CPNE4" Computational M19045 GCM_IL6ST Neighborhood of IL6ST MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.08E-04 1.75E-01 4.85E-03 3.54E-02 23 54 "ATP2B2,MAP4K4,SH2B1,GOLGA7,ANKFY1,IL6ST,KCNJ10,IPO5,MYO9A,RDX,CCDC25,SIRT2,FAM219A,GLT8D1,ERBIN,TACC1,DDHD2,FBXW11,ATMIN,TNS2,GORASP1,CLDND1,RTN4" Computational M9347 MODULE_176 Signaling. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.58E-04 2.16E-01 5.83E-03 4.26E-02 70 230 "ADCYAP1R1,ADRB2,SPARCL1,SRPX,ANK3,APLP1,AQP4,AZGP1,C5,CBLN1,CLDN10,RGN,CDH2,CHGA,CHGB,CHI3L2,CP,CPS1,CRMP1,KIAA0040,CX3CR1,DPP6,RCAN2,EPHB1,F3,FCGR3A,OLFM1,GABRB3,GAD1,GAP43,WASF3,GATM,GJB1,RAPGEF1,GRIK1,GSTM5,IGF1,ITIH2,KCNB1,MAOB,MEF2C,MYBPC1,NELL1,NEUROD1,NNAT,NOS1,NPY,NOVA1,NPTX1,NTRK3,OMG,PAH,PLXNB1,C19orf57,PPP3CA,PTH1R,PTPRD,PTPRG,PTPRO,RGS7,RPS6KA2,RXRG,ST6GAL1,SMTN,MLC1,SYT1,TF,TIMP4,UGT8,SCG2" Computational M12622 MODULE_379 Genes in the cancer module 379. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.31E-04 2.77E-01 7.18E-03 5.24E-02 63 204 "NDRG2,SEMA7A,ATP6V1G2,RGS9,CDK5R2,CCK,ENTPD2,REPS2,MAGI1,ASIC3,TAOK2,SLC22A6,NRXN1,AKAP7,NRG2,RIMS2,FAM131B,ECE2,KIAA0586,ZBTB24,FAM13A,SRPK3,APC2,ACTL6B,FLT1,AKAP3,TACC2,PRELID3A,NSG1,RUNDC3A,CRCP,GRIK5,GRM2,HSD17B1,KCND3,KCNN1,KCNQ3,L1CAM,SCAMP5,MSI1,TAGLN3,NNAT,PGAM2,JAKMIP1,PLIN1,PTPRN,KCTD17,EXD2,EMID1,SCN2B,NTNG1,FAM214B,KIF21B,SOX10,SSTR2,ABCC8,VAMP1,SYT5,ADGRL3,ACSL6,SEZ6L,TRPM2,SLC17A7" Computational M16447 MODULE_112 Genes in the cancer module 112. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.34E-04 2.80E-01 7.18E-03 5.24E-02 77 260 "ADCYAP1R1,ADRB2,SPARCL1,SRPX,ANK3,APLP1,AQP4,AZGP1,C5,CBLN1,CLDN10,RGN,CDH2,CHGA,CHGB,CHI3L2,CHRNB2,CP,CPS1,CRMP1,KIAA0040,CX3CR1,DPP6,RCAN2,EPHB1,F3,FCGR3A,OLFM1,C1orf61,GABRB3,GAD1,GAP43,WASF3,GATM,GJB1,RAPGEF1,GRIK1,GSTM5,IGF1,ITIH2,KCNB1,MAOB,MEF2C,MYBPC1,NELL1,NEUROD1,NNAT,NOS1,NPY,NOVA1,NPTX1,NTRK3,OMG,PAH,PIK3CD,PLCB2,PLXNB1,C19orf57,PPP3CA,PKIA,PTH1R,PTPRD,PTPRG,PTPRO,RGS7,RPS6KA2,RXRG,ST6GAL1,SLC1A3,SMTN,MLC1,SYT1,TF,TIMP4,UGT8,VSNL1,SCG2" Computational M15442 MODULE_242 Genes in the cancer module 242. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.47E-04 3.74E-01 9.35E-03 6.83E-02 65 214 "NDRG2,SEMA7A,ATP6V1G2,RGS9,CDK5R2,CCK,ENTPD2,REPS2,MAGI1,ASIC3,TAOK2,SLC22A6,NRXN1,AKAP7,NRG2,RIMS2,FAM131B,ECE2,KIAA0586,ZBTB24,FAM13A,SRPK3,APC2,ACTL6B,FLT1,AKAP3,TACC2,RASL10A,PRELID3A,NSG1,RUNDC3A,CRCP,GNG4,GRIK5,GRM2,HSD17B1,KCND3,KCNN1,KCNQ3,L1CAM,SCAMP5,MSI1,TAGLN3,NNAT,PGAM2,JAKMIP1,PLIN1,PTPRN,KCTD17,EXD2,EMID1,SCN2B,NTNG1,FAM214B,KIF21B,SOX10,SSTR2,ABCC8,VAMP1,SYT5,ADGRL3,ACSL6,SEZ6L,TRPM2,SLC17A7" Computational M17509 MODULE_438 Intermediate filaments and MT. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.43E-04 5.38E-01 1.31E-02 9.59E-02 26 68 "AMPH,PKP4,GAS7,CCNT1,INA,SNPH,DYNC1I1,DTNB,TUBB4A,TACC2,STMN2,FAM107A,KIF5A,KIF5C,KLC1,STMN1,MAP2,MAPT,MID1,MYH7,NUMA1,PALM,SEPT4,SH3GL2,SNAP25,STX1A" Computational M9103 MODULE_389 Breast cancer expression clusters. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.15E-03 9.62E-01 2.29E-02 1.67E-01 64 217 "ACTN2,FMNL2,GALNT13,GRAMD1B,BBOX1,PDE8B,SYT6,ARHGEF25,DLGAP2,CFL2,HINFP,GDA,CNTNAP2,SPOCK3,CD99L2,DYNC1I1,ECM2,SEZ6L2,PHF20L1,CDKL3,DNAJC27,FOXG1,AKAP3,JPH4,FAXC,CYP46A1,CSDC2,LINGO1,AGBL5,KCND1,KIFC3,PAXBP1,SNTG1,CNTN3,GDAP1L1,FA2H,LRRN3,PRPSAP2,PBRM1,LGI2,HSPA4L,RPH3A,OGDHL,FAIM2,NMNAT2,EMC1,SST,NSFL1C,SYT11,PHF24,FAM189A1,NSD1,SIK3,TF,ACTR6,ZFP91,RBFOX2,ZKSCAN5,PRTFDC1,DNALI1,GAL3ST3,TMEM163,ACTR3B,CPNE4" Computational M7699 GCM_ERBB2IP Neighborhood of ERBB2IP MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.40E-03 1.00E+00 2.73E-02 2.00E-01 24 64 "BBS2,MTMR2,MAP4K4,RNF14,GOLGA7,VPS13B,KIAA1109,ANKFY1,NPTN,CAB39,AHCYL1,IL6ST,PRKAB2,OCIAD1,RDX,ARFGAP1,ERBIN,DDHD2,FBXW11,EHBP1,FRYL,DICER1,GORASP1,TBC1D15" Computational M9982 MODULE_2 DRG (dorsal root ganglia) genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.86E-03 1.00E+00 3.54E-02 2.58E-01 103 384 "SERPINA3,ACTN1,MTUS1,ALCAM,SRPX,ANK3,GAS7,BCAS1,ARHGDIG,CADPS,DDX3Y,CADM3,ATP6V0A1,DST,SGCE,USP6,INA,UBE2L6,CHGB,SLIT2,PPT2,FADS2,CNN3,AKAP12,CLIP3,ARHGEF10,SNAP91,SV2B,DMD,DNM1,DYNC1I1,ECM2,EEF1A2,OPTN,ENO2,EPB41L2,RCAN2,EPS8,FABP7,FCGRT,FGF1,OLFM1,FGFR1,CAP2,GABBR1,CHL1,GAP43,GATM,AHDC1,GLS,STMN2,GRB10,GYG1,ITGA7,KIF5C,L1CAM,MAOB,MBNL1,MBP,CD200,MX1,NCAM1,NEFM,NPY,NTRK2,PCDH9,ENPP2,PLEC,FXYD1,PLP1,SCHIP1,PPP1R1A,PTN,PTPN13,QDPR,RTN1,S100B,SATB1,SCP2,ABLIM3,SMTN,SNAP25,SOX10,SPP1,TSPYL2,SST,EPB41L3,MAPK8IP3,RGL1,SYT11,SYT1,ZEB1,TRIM2,TGFBR3,THRA,TNFRSF1B,TPM1,TPM2,CADM1,VSNL1,ZIC1,SCG2,PCBP4" Computational M2707 MODULE_426 Genes in the cancer module 426. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.25E-03 1.00E+00 4.18E-02 3.06E-01 30 88 "SRPX,CNTNAP1,APOC1,SHROOM2,BCHE,CFAP410,MAP7,CLDN10,CHN2,MS4A7,CNRIP1,PHYHIP,RPS6KL1,DYNC1I1,F5,ZIC4,CSPG5,AGBL5,KIF5C,KLRC3,NUCB2,PCSK1,MAPK4,BCAN,SYBU,SLC8A2,SCN3B,SST,MLC1,SPHK2" Computational M13176 MODULE_206 Genes in the cancer module 206. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.34E-03 1.00E+00 4.25E-02 3.11E-01 47 154 "ARID1A,GRAMD1B,GPR146,PROM1,GYG2,FADS2,COL4A5,CSF1,SEC24C,IPCEF1,USP6NL,IST1,KIAA0087,PLEKHM1,SRGAP3,ECM2,EFNB3,PHF20L1,ST3GAL6,CINP,CBX1,PCLO,GRIK1,FICD,ADAMTS6,ATXN2L,HMGCR,MAP6,MBNL1,MMP17,MOBP,MRPL42,DDX25,NUCB2,TREM2,CNTN3,PIGG,SCN8A,PPP4R3A,NMNAT2,EMC1,SYT11,R3HDM1,TRIO,REEP1,ZNF184,DNALI1" Computational M2175 MODULE_129 Signaling. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.44E-03 1.00E+00 4.34E-02 3.17E-01 63 219 "KDM5D,BCAR3,BBOX1,APOC1,CASK,ARHGDIG,ATP1A2,ALDH7A1,NOL4,BCHE,PROM1,BAIAP3,SLC16A4,CHRNB2,CRHBP,AKAP12,CRMP1,ARHGEF10,ARHGEF4,HDAC9,GPRASP1,DBN1,EML1,EFEMP1,FGFR1,FOLR2,KHDRBS3,TMEM8B,SYT17,WASF3,GRIN1,SCRG1,IGF1,KCNA1,KCNB1,KCNK2,MX1,NAP1L3,NPY,NOVA2,PCDH9,PDE2A,PDYN,SERPINI1,PLXNB1,SCHIP1,PTPRE,RFX2,RNASE1,ZNF821,ZNF365,SMTN,SLC6A1,SPP1,PEG10,RGL1,SYNE2,PLCB1,TPM2,TRO,VLDLR,TRIM9,SSPN" Computational M4874 MODULE_26 Genes in the cancer module 26. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.52E-03 1.00E+00 4.40E-02 3.21E-01 60 207 "ACTN2,FMNL2,GALNT13,ADORA1,BBOX1,APLP1,PDE8B,BMPR1B,SYT6,ARHGEF25,DLGAP2,CFL2,CLOCK,HINFP,GDA,SPOCK3,CD99L2,DYNC1I1,SEZ6L2,DNAJC27,BAIAP2,CAP2,FOXF2,AKAP3,FAXC,CYP46A1,LINGO1,AGBL5,KCND1,KIFC3,PAXBP1,NTRK3,SNTG1,GDAP1L1,ZNF655,FA2H,PRPSAP2,ZDHHC4,PBRM1,LGI2,HSPA4L,RPH3A,OGDHL,FAIM2,SST,NSFL1C,TRIM2,PHF24,NSD1,SIK3,KHDC1,ACTR6,RBFOX2,ZKSCAN5,TBC1D15,PRTFDC1,GAL3ST3,TMEM163,ACTR3B,CPNE4" Computational M10555 GCM_GSPT1 Neighborhood of GSPT1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.69E-03 1.00E+00 4.60E-02 3.36E-01 50 167 "RALGAPA1,KIDINS220,AP2A1,MARK4,BTRC,MTMR7,ZBED1,EVI5L,HECTD1,IQCK,SH2B1,CS,EDNRA,ASB3,ING4,DCTN4,LINC01278,UBE2E3,FOXO3,JKAMP,ATP2C1,ZNF512,BRPF3,PRRC2B,MSL1,C5orf24,IPO5,MYO9A,NFYA,TNPO2,PPM1B,OCIAD1,UBR7,KLHL11,COPZ1,CHD9,ARFGAP1,TTC17,USP33,POGZ,EHBP1,ZNF384,RPL7L1,GORASP1,CFAP298,ZFAND5,UPF3A,WNK1,AAAS,SOCS4" MicroRNA hsa-miR-144:mirSVR_highEffct hsa-miR-144:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.55E-217 4.80E-213 4.80E-213 4.43E-212 511 1990 "SDE2,ACADM,NCKAP5,NBAT1,ARID1A,CSMD3,NDRG3,KLRC4,CCDC85A,AXIN2,GRAMD1B,PWWP2A,KIDINS220,SLC44A5,ZNF608,GPR158,WDR35,OSBPL8,TAOK1,SPARCL1,ALCAM,FAM135A,ANK2,APAF1,UPRT,ALS2,CACHD1,BCAS1,LGR5,CDC14B,MIER1,ARHGAP5,CADPS,ASCL1,MARCH3,ASPH,ZSCAN18,DACT3,NCOA1,NUMB,ATM,ATP2B1,ATP2B2,ALDH7A1,B3GALT2,NOL4,ATP6V1G2,BACH1,MPDZ,NRP2,BMPR1B,CDK5R1,DST,ARHGEF7,NAE1,JAZF1,OSGIN2,CA8,CACNA2D1,CACNB2,CALB1,CALM1,CH25H,ISPD,RUNX1T1,PRC1,CCNH,USP6,TMEM257,C1orf52,CDH2,MAGI1,CFL2,COPB2,SOCS6,CHM,CHN2,CASC2,B4GALT6,JAM2,NDST3,LHX2,KMT2C,FBXO7,TJP2,C4orf33,QKI,CNN3,CNR1,ARMC8,AKAP6,WHRN,SLC25A27,COX4I1,ACBD5,MYRIP,ZFP28,CPS1,AKAP12,GDA,CSF1,OSBPL3,CSNK1G3,ATRNL1,NCAN,SOCS5,PHACTR3,PPP1R16B,CTH,PUM1,ST18,USP6NL,CYBB,DOCK4,HDAC9,TOX,LONRF1,TBC1D5,MATR3,KCTD8,DNAJC6,C8orf34,ZEB2,ZBTB24,MYEF2,HP1BP3,FBXL5,CEP170,ZC3H11A,DDX46,RHOBTB1,SNAP91,SACS,ZNF582-AS1,DLX1,GRIN3A,DMD,USP3,CPEB2,ABI1,RCAN1,ARRDC4,DTNA,EBF1,EDN1,ANKRD46,RASGRP1,FRY,MBNL2,GOLGA7,EIF4G2,IRAK4,ELAVL2,RGS17,CALCRL,EPB41L2,LRRC17,EPHA5,KCNMB2,RABEPK,STX2,SRRM1,EPS8,ZNF585B,TMEM132C,ACSL4,EFEMP1,DLC1,ST3GAL6,CEP78,MED12L,GTF2IRD2,FGF13,MAD2L2,POLK,SUCO,FOXG1,CAP2,PCYOX1,SYNCRIP,ATP13A4,FLT1,PSD2,SGIP1,DCTN2,ZCCHC17,CAMKK2,ATP6V1H,KHDRBS3,ST6GALNAC3,PNMA2,MEGF10,GABRA1,BRPF3,RAPGEF6,ARPP21,NCKAP1,GART,KIAA1841,GCNT2,MSTN,AHDC1,GFRA2,PPARGC1A,GLDC,GLI2,GLRB,GLS,ZNF638,CBX1,INSM2,LUZP2,GNAL,FERMT2,GPD2,GPM6B,LPAR4,NUDT21,RAPGEF4,GRIA4,GRIK2,NR3C1,PRDM5,GRM5,GRM7,KIF3A,LINC00839,COQ10A,PSIP1,FAM107A,WIF1,RASSF8,UBE2QL1,ZHX1,FRMD3,MIER3,HMGCR,HNRNPK,HSF2,ZNF181,SOWAHA,IGFBP1,ZIC5,RBPJ,USP54,NME9,ITGAV,JAK2,SLC35G1,KCNA4,KCND2,KCNK2,CYP27C1,INSYN2,PAXBP1,HECTD2,NCOA7,SMAD1,SMAD9,MAOB,MAP4,MARK1,MATN2,MBNL1,LRP1B,MEIS1,MEIS2,SRSF12,KITLG,PPM1L,MITF,ERICH3,MSR1,CTNNA3,BEX5,NAP1L1,NAP1L3,NCF2,NDUFA5,NF1,OTOGL,NFE2L2,ALDH1L2,NOS1,NPTX1,IGSF11,LOC100128398,GPR137C,CNTN3,PRTG,PDE4A,PDGFRA,SLC10A4,PFKFB2,PIK3C2A,PIK3R1,FAM218A,A2ML1,CCSER2,SNX10,FAM216A,PCDH18,HMGCLL1,MTRF1L,RC3H2,LRP12,SCHIP1,PRRX1,ING3,SPATA6,POU3F2,PPM1B,PPP2R5E,PRKACB,PKIA,PKN2,MAPK4,EPDR1,MAPK9,GRAMD1C,DIRAS2,PRPSAP2,DCHS2,VPS13C,SYTL2,CNTLN,PTHLH,ELOVL2,TMEM260,PTPRG,C1orf109,PTX3,ZNF615,USP47,FAT4,FAM184A,RAP1GDS1,ENOX1,ZNF493,OXR1,RASGRF1,DBX2,RBBP6,ZDHHC14,RET,RFX4,RGS7,SLC25A36,NUDT11,RNASEL,RPRD1A,ZFHX4,CCDC82,ZNF532,SETD5,RAVER2,GSTCD,ROBO2,RPE,ZC3H14,TCP11L1,LRRK2,LGR4,ZNF568,FAM192A,AP1AR,SALL1,SEMA6D,SCN2A,SMPD3,SLC30A10,CASC3,FOXRED1,SUPT20H,RASA3,SGK1,FNDC3A,CNKSR2,SEC31A,ANKRD6,RUFY2,SEPHS1,RAB3GAP1,CCDC88A,SHANK2,SLC12A2,SLC15A2,EFHD1,SLC20A2,SPHKAP,SORCS3,SMARCE1,LIMCH1,RIMS1,PALLD,FAM126B,MYO16,UNC80,SON,PDZD2,SOX1,MYT1L,BDP1,SP4,NPAS3,CAMTA2,ZNF302,SSTR2,NKAIN2,SS18,ST5,CEP68,RGL1,STXBP1,KLHL7,SYT11,ZC3H4,VPS13A,ADAMTS17,PLCB1,ANKRD28,C12orf76,ATP11A,DDHD2,MCF2L,CAMSAP2,FBXW11,DMXL2,SATB2,TCF7L2,ZEB1,RPGRIP1L,TCF12,WASHC4,CLASP1,NAT16,RALYL,GPRIN3,TEK,FAM200B,SIRT1,ZFPM2,ITGB3BP,TJP1,DDHD1,BHLHB9,TLR4,ZFP91,TMPO,TP53BP2,TPD52,RGMB,SYNPO2,TRIO,STXBP4,ZMYND8,DCBLD1,TSN,ANKRD20A2,SGK3,TUBB1,RPL7L1,DNAJC12,PLEKHH2,RICTOR,GUSBP1,SLC13A3,PCDH20,ZFP37,ZBTB14,ZIC1,KCNT2,ZNF540,FMN2,ZBTB38,TMEM237,ZSCAN26,DPYSL5,SPIRE1,ZNF225,MFF,CADM2,PRDM2,RGMA,STOX2,RNF103,ADAMTS9,SCG2,CIAPIN1,NAV3,TMEM163,WNK3,SLC17A6,FAM13C,AMN1,FZD3,DOCK8,RTN4,PAK5,KAT6A,PHTF2,JMJD1C,NLRP3,ZNF248,RNF170,FRMD6,IFT88,NETO2,SLC4A10,GAN,SENP7" MicroRNA hsa-miR-493*:mirSVR_highEffct hsa-miR-493*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-212 9.03E-209 4.51E-209 4.16E-208 496 1910 "ABAT,CLK4,NCKAP5,NBAT1,ARID1A,CSMD3,FMNL2,TMEM132B,GALNT13,GRAMD1B,UNC5A,BEND6,SLC24A4,ZNF608,KLHL13,PCDH19,RTL9,OSBPL6,WDR35,OSBPL8,SPARCL1,ALCAM,SRPX,ABCD2,FAM135A,MRTFA,ANK2,LCORL,MAP4K3,PHF12,PPFIA1,ANXA7,ALS2,CACHD1,API5,USP37,APP,SHTN1,MIER1,MADD,TMEFF1,ARNTL,CADPS,ZBTB10,NCOA1,RASL11B,ATP1B3,ATP2A2,BCL7A,NRP2,BLM,DST,ARHGEF7,FUBP1,OSGIN2,CACNB2,CALM1,KALRN,PTBP2,VSTM2A,MAP7,USP6,USP2,DGKI,CDH2,CDH10,LRRFIP1,LOC730101,CLGN,SRSF11,SOCS6,B4GALT6,NDST3,NRXN3,PLAA,NRXN1,NIPBL,CNN3,IQCK,AKAP6,COL9A3,AHCTF1,RTTN,TOGARAM2,ZNF521,MFSD4A,HS3ST5,CLOCK,GDA,LRIG1,PDE4DIP,FAM169A,ERC2,CTNND2,KIAA0408,BOC,TOX,ZFYVE16,KCTD8,PABPC5,BRINP1,ELMSAN1,ZNF804A,C8orf34,ZEB2,HEPH,HP1BP3,CEP170,DDX46,SNAP91,SACS,AK5,DLG2,GRIN3A,RAB39B,NR1D2,CDON,DNM2,ABI1,ECM2,DYRK1A,EDIL3,EDNRB,ATL1,HIPK3,FCF1,RASGRP1,FRY,EFNA3,RBM12,FAM13A,PHF20L1,MBNL2,TENM1,RGS17,GPHN,DENND4A,EXTL2,EYA1,F3,ABCA8,ACSL4,TAOK3,SCML2,FCGR1A,SEC24B,POLK,CAP2,PSD2,SLC37A3,C2orf88,NBEA,TACC2,HVCN1,USP16,TPK1,ATP6V1H,ATP2C1,DACH2,STAU2,ABLIM2,MEGF11,GABRA1,GABRA2,GABRA5,GALNT15,GABRG2,TRAF3IP2,GAD1,ZMYND11,RAPGEF6,SALL3,ZNF234,NEK6,DISC1,GART,WASF3,LRRC37A6P,CPLX2,MYOZ2,GATM,MSTN,ARFIP1,AHDC1,ADAM28,GFRA2,PPARGC1A,MALT1,ZNF276,RNPS1,HPGDS,TNRC6A,PCDH11X,KDM2B,INSM2,FERMT2,CNDP1,PRUNE2,GPM6A,GPM6B,STON1,ATP2B1-AS1,DIDO1,GRIA4,GRM1,GRM5,TMEM25,AP4S1,NXPH2,MIER3,HMGCR,ZNF491,OPALIN,TCEAL6,SMAP1,IFI16,ZNF181,MYLK2,IGFBP1,LRRCC1,IGSF1,LIX1,RIPPLY2,ZNF385B,LRRTM3,ITGAM,ITGAV,ITPKB,SLC35G1,KCNJ10,KCNK1,KCNMA1,KIF5A,KIT,STXBP5,L1CAM,LAMA2,LAMP2,INSYN2,LIG4,PAXBP1,HECTD2,ARHGAP12,NCOA7,SMAD1,MAP4,MAP6,TM6SF1,MEF2C,MGAT3,POC1B,AFDN,MOBP,GIT1,MSR1,CTNNA3,MTTP,RSPO2,PABPC1L2A,NAP1L1,NAP1L2,NAP1L3,ZC3H12B,NELL2,NF1,NOVA1,LOC100128398,GPR137C,PCDH9,PCSK5,CDK18,PDE4D,PDGFRA,GNG2,OLA1,NLGN3,CAMKV,PIK3C2A,PIK3R1,XRN1,FAM216A,PCDH18,SMIM7,PURG,PDZRN4,PMP22,TRHDE,MAPKAP1,RC3H2,LRP12,SCHIP1,ING3,SPATA6,SLC36A4,NXPH1,MED1,MINDY2,PPP2R2C,LRRN3,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,PKIA,PRKCZ,GDPD1,DCHS2,KLK6,SLC22A23,SIDT1,MDGA2,PTCH1,BDNF-AS,PTN,PTPRD,ZNF615,SLC25A41,OXR1,RASGRF2,RBBP6,VEPH1,REV3L,ERI2,MORC4,FIGN,RFX4,RGS10,SLC25A36,NUDT11,ZFHX4,CCDC82,ZNF532,CARF,ROBO1,ROBO2,ELP2,CCDC102B,RPE,RPE65,BAALC,SPIN3,ZC3H14,TCP11L1,WLS,CLIP1,ZNF331,SALL1,MIR124-2HG,ATXN7,SCN2A,FNIP1,ZFP2,SUPT20H,RASA3,DOCK10,MAGI3,CHD9,FNDC3A,FHOD3,NLGN1,ST3GAL3,NUBPL,CLSTN1,WDR37,BTBD3,DHX30,LRRC55,YPEL4,CCDC88A,ELMO2,SLC20A2,MAST1,SORCS3,SMARCE1,LIMCH1,MBD5,PDZRN3,PDZD2,SOX1,MYT1L,KIF21B,KDM3A,SP4,EMC1,MYCBP2,KDM4C,ZC3H13,KIF1B,RBM26,NPAS3,RAP1GAP2,LMO3,SRPK2,POGZ,LARP4,SS18,ERBIN,ST5,NEK4,SEPT8,DIP2A,SULF2,SEPT3,NECAB1,SYNE2,PLCB1,TMEM150C,SYT1,ANKRD28,SYT4,TAC1,ANKRD12,MTCL1,CAMTA1,CAMSAP2,ADGRL3,AGTPBP1,FBXW11,ANO4,TCEA1,EHBP1,TCF7L2,ZEB1,TRIM2,RPGRIP1L,WASHC4,CLASP1,SZT2,WDR7,SYNE1,DOCK9,PCDHB7,PCDHAC2,PUM2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CCDC173,TEX15,SIK3,ITGB3BP,LEFTY2,TIAM1,HEY1,TLL2,HEY2,TMOD1,TPM1,TPM3,ZNF384,STXBP4,TRPC3,TRPS1,ZMYND8,RFTN2,ZNF610,EIF4ENIF1,UBE3A,UGT8,DNAJC12,PITPNB,USP1,LGI4,ZFP37,ZIC2,ELFN1,ZNF540,TCEAL7,ZBTB38,TMEM237,EML6,PLPPR5,WNK1,EVI5,STOX2,PRDM8,TMEM178A,SCG2,VPS35L,NAV2,WNK3,C12orf4,PDSS2,RGS7BP,FAM13C,JMJD1C,ZNF248,SNX14,FXR1,NETO1,DPF3,JPH3" MicroRNA hsa-miR-101:mirSVR_lowEffct hsa-miR-101:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.97E-212 4.47E-208 1.49E-208 1.37E-207 501 1956 "CPNE2,ACADM,ASIC1,NCKAP5,NBAT1,CSMD3,FMNL2,TMEM132B,KLRC4,ADCY6,AXIN2,PWWP2A,PTCHD1,KIDINS220,KLHL13,KCTD16,TXNDC16,SPARCL1,ALCAM,AMPH,OGT,EP400,APBB1,APC,GPAM,LRRC4C,PDXK,ZFYVE28,ARNTL,ARRB1,NUMB,DDX3Y,ATM,SLC4A4,EIF4G3,ATP2B1,ATP2B2,MTMR9,NOL4,RIPK1,DOCK11,LINC00847,NRP2,BID,DST,SYNJ1,FUBP1,NAE1,CACNA1D,CALB1,KALRN,PTBP2,CAMK2D,CAMK2G,VXN,CAST,CH25H,CBR1,USP6,USP2,CD38,DGKI,ARHGEF2,SEPT7,CDH2,CDO1,NOG,SOCS6,CHM,PLEKHB1,CASC2,LHX2,KMT2C,DLGAP3,RAB28,KIAA1549L,COG1,FBXO7,QKI,IGLON5,CNN3,AKAP6,SLC25A27,LETMD1,COL11A2,SLC4A8,ACBD5,ZNF521,MFSD4A,SLC35F1,CPS1,CREM,ENTPD4,RBM39,CRY2,CSF1,MICAL2,ATRNL1,NCAN,FAM169A,APPL1,PUM1,RIMS2,ST18,USP6NL,EDRF1,CCDC144A,KIAA0408,GPRASP1,TOX,KCTD8,DAPK1,YTHDC1,DNAJC6,ZNF804A,ZEB2,ZBTB24,MYEF2,CEP170,RHOBTB1,SNAP91,SACS,SV2B,SPOCK3,G3BP2,WDR20,DLG3,DLX1,DMD,CASP8AP2,DPYSL2,ABI1,PDCD6IP,ECM2,E2F6,AASDH,EBF1,SNX29,EDN1,EDNRB,ANKRD46,SYT15,FRY,YAF2,EFNB3,KMT5B,EGR3,GOLGA7,EIF4G2,ELAVL2,MRNIP,RGS17,ELN,STARD3NL,DCTN4,USPL1,VPS13B,EPB41L1,EPB41L2,KCNMB2,ENPP6,RABEPK,SRRM1,EPS8,CDKL3,RCSD1,RRAGB,ADGRV1,EFEMP1,ATP8A1,TOMM40L,FKTN,MED12L,FGFR3,TMEM164,CAMSAP1,FHL1,POLK,SEC23B,CAP2,RGPD5,FLT1,ANKFY1,C2orf88,ZCCHC17,TACC2,HVCN1,TPK1,ATP6V1H,DOT1L,OGA,PHYHIPL,ZMAT1,DKK3,MEGF10,GAB1,GABRA1,GABRA5,GABRB1,GABRG1,CAB39,GAD1,BRPF3,SALL3,NCKAP1,MTHFD2,C15orf41,ATP8A2,GART,KIAA1841,TUBGCP4,GFAP,ADAM28,GFRA2,PPARGC1A,RND1,GLDC,TOX3,LOXL3,FERMT2,PRUNE2,GPR19,GPR22,NUDT21,GPR37,TMEM121B,GRIA2,GRIK3,NR3C1,GRM3,RNF165,LINC01551,FAM222A,WIF1,UBE2QL1,ZHX1,AGBL5,AGFG1,HSF2,CELF5,IGFBP1,RBPJ,DOCK7,USP54,IL12A,ZNF678,INPP5B,TUBB2B,LRRTM3,OLFM3,KCNA4,KCNA6,KCNH2,KCNK2,KIF2A,KLC1,INSYN2,PAXBP1,HECTD2,FGFBP3,ARHGAP12,C2orf80,SMAD1,SMAD9,AQP11,MATN2,SHC3,MEIS1,MEIS2,PPM1L,AFDN,WDR49,CCDC80,JAKMIP3,ADAM22,CTNNA3,RSPO2,NEXMIF,BEX5,NCAM2,NFIA,NFE2L2,NNAT,PCBP3,NTRK2,IGSF11,OMG,OPA1,CNTN3,PBX1,PDE4A,PDE4D,PDGFRA,PFKFB2,SSH1,FTO,PCDH18,HMGCLL1,PLXNB1,STRN3,EXOSC10,PRRX1,POU3F2,CCDC144B,LRRN3,CRLS1,PTPA,PPP2R5E,PKIA,RAB39A,PKN2,EPDR1,MAPK9,CNNM2,SIDT1,CNTLN,PTAFR,PTCH1,BDNF-AS,PTN,TMEM260,ZIK1,PTPN13,PTPRO,TMEM231,SH3TC2,FAT4,FAM184A,RASGRF2,RBBP6,BSDC1,SLC6A15,RET,GTDC1,SLC25A36,RNASEL,RPE,NEK11,SPIN3,ZC3H14,MCMBP,PRR5L,ACER3,CNTNAP3,PTGR2,FAM161B,MEG3,ATAT1,WLS,CLIP1,ZNF568,TRAPPC13,SALL1,ATXN1,SCP2,SMPD3,ELMOD1,FOXRED1,SFPQ,ITSN1,NTNG1,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,ANKRD6,NUBPL,PAAF1,CLSTN1,ABLIM3,EPN2,DHX30,SMTN,WDR47,ZNF430,SLC6A11,SEPHS1,RAB3GAP1,ARHGEF40,SHANK2,SLC20A2,SMARCE1,RCOR3,SNCA,SNRPN,UNC80,SCN3B,SOX1,TRERF1,SOX2,SOX3,SOX11,KDM3A,SP4,PEG10,ZC3H13,SPTAN1,KIF1B,RBM26,NPAS3,C11orf87,ZNF621,CLASP2,ITPRID2,SAMSN1,EPB41L3,ZC4H2,SS18,NXT2,CEP68,SULF2,KLHL7,SYT11,FGD4,SYNE2,ARHGEF9,ADAMTS17,PLCB1,SYPL1,COBL,ANKRD28,C12orf76,TAC1,TACR1,PJA1,DDHD2,MCF2L,TAF9,PDLIM2,ALG1,TBCEL,ANO4,TRIM2,RPGRIP1L,WASHC4,USP22,RALYL,GPRIN3,TEK,FAM200B,PMS2CL,CRB1,C18orf54,ITGB3BP,AP4E1,GPR161,AKTIP,GZF1,TJP1,HEY2,SEZ6L,TPD52,SYNPO2,METTL3,TRIO,STXBP4,SGK3,TUBB1,UGT8,SLAIN1,ZNF709,WIPF1,P2RY12,WRN,CLDND1,RICTOR,GUSBP1,SLC13A3,ZNF24,ZNF540,FMN2,ZNF154,TMEM237,ZNF177,PLPPR5,ZFAND5,MEIS3,WNK1,CA10,TMEM178A,SCG2,HPS4,PCDH15,TMEM163,WNK3,PDSS2,RGS7BP,FAM13C,DOCK8,RTN4,PAK5,HNRNPA3,TRAM2-AS1,ADAMTS10,SSPN,FXR1,IFT88,NETO2,SLC4A10,JPH3" MicroRNA hsa-miR-466:mirSVR_highEffct hsa-miR-466:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.59E-211 3.14E-207 7.84E-208 7.23E-207 496 1924 "RALGAPA1,ACADM,NCKAP5,FMNL2,KLHL32,ERMN,PLEKHH1,PWWP2A,ESYT2,KIDINS220,BEND6,INTS2,MTUS1,GPR158,RTL9,OSBPL8,ABCD2,ARHGAP20,PCDH10,FAM135A,AMPH,ANK2,ANK3,USP28,PPFIA2,PARG,EPB41L5,API5,LGR5,MIER1,IGDCC4,ARHGAP5,ASCL1,BRINP2,SLC4A4,STX16,ATP2A2,N4BP2L1,ATP6V1G2,ADGRB3,CDK5R1,DST,SYNJ1,ARHGEF7,JAZF1,WASF1,CA8,CACNA2D1,THSD7A,SLC25A14,CLDN10,KRIT1,CDH2,LRRFIP1,LGI1,CIART,CFL2,RCBTB2,SRSF11,SOCS6,MS4A7,SYNPR,B4GALT6,RAB28,CLCN4,CLTA,QKI,TMEM184B,MAP4K4,FHL5,CNN3,CNR1,ARMC8,FAM149A,AKAP6,COL4A5,LETMD1,SLC4A8,ABI3BP,BAG4,MYRIP,CNRIP1,CPS1,CLOCK,OSBPL3,ATRNL1,SIPA1L1,VCAN,PDE4DIP,PLXNA4,DZIP3,ERC2,CTH,NRSN1,PUM1,BOC,DOCK4,ARHGAP24,ZFYVE16,KIF26A,KCTD8,DAPK1,PABPC5,DCC,JAKMIP2,C8orf34,ZEB2,ZBTB24,MYEF2,KIAA0753,CEP170,KLHL3,RHOBTB1,SNAP91,SACS,SPOCK3,SV2A,SGSM2,ARNT2,DMD,NR1D2,CPEB2,DPP6,DRD1,PDCD6IP,RCAN1,ARRDC4,DTNB,ECM2,DYRK1A,ABCC9,GOLT1B,EBF1,SGK2,FRY,RBM12,PHF20L1,MBNL2,EGR3,EIF4G2,PLEKHA1,STARD3NL,PAN3,EIF1,OLIG2,EPHA5,KCNMB2,RABEPK,SRRM1,EPS8,DENND4A,EFS,ZNF549,ETV1,F5,CLVS1,ZNF461,FABP7,ACSL4,SCML2,DLC1,GORAB,MED12L,CAMSAP1,POLK,MEX3B,FOXG1,FOXO3,SPECC1,UFM1,ERGIC3,CELF1,ST6GALNAC3,STAU2,DOT1L,STAG2,MEGF11,GABRA1,GABRA2,GAD2,GALC,ZNF274,NCKAP1,ERAP1,GATM,IGSF5,WASHC2A,ADAM28,BRD8,GLDC,SPIN1,GLS,TOX3,PCDH11X,ZNF638,GNAO1,LNX1,ADGRA3,GPM6A,CCDC184,GPR22,EML4,GPR37,CECR2,RAPGEF4,ATP2B1-AS1,GRIA2,GRID1,RFFL,NR3C1,GRM3,KIF3A,LINC01551,SOX21,PSIP1,GUCY1B1,NXPH2,FRMD3,ELOVL5,ZNF491,MSL1,LINC00667,ZNF181,ZIC5,TJAP1,SCIN,IL11RA,INPP5B,INSM1,JAK1,SLC35G1,KCNA2,KCNK1,KIT,LAMP2,PAXBP1,HECTD2,NCOA7,SMAD9,MAPT,MARK1,LDLRAD3,TM6SF1,MEF2C,MEIS1,KITLG,AFDN,ERICH3,ZNF680,MRPL42,SESN3,N6AMT1,MYO6,MYO9A,NAP1L1,NCAM2,NEFH,NF1,SLCO1C1,VWA2,CNOT4,NPY,NOVA1,SLC11A2,NRCAM,NRDC,SETD4,IGSF11,CHAMP1,OGG1,CLDN11,P2RX7,GPR137C,PCDH8,PCDH9,PCSK2,PRTG,PDE3B,PDE4B,PDGFRA,OLA1,ABCB1,PKD1,XRN1,PLCL1,JAKMIP1,PCDH18,PMP22,STRN3,PRRX1,ING3,SH3KBP1,POLR2F,MINDY2,TATDN3,PPP2R5E,CEP41,PRKCB,PKN2,MAPK9,DIRAS2,PROX1,RELN,WBP1L,SYTL2,SIDT1,GON4L,SNRK,CNTLN,PTCH1,PTPRD,C1orf109,PEX5,MARCH1,CEP97,RALGDS,FAT4,FAM184A,NWD1,ZNF493,OXR1,ARID4A,VEPH1,KHDRBS2,ZDHHC14,RDX,ZMAT4,REV3L,RFX2,RFX3,RGS4,RGS12,ARHGEF10L,SLC25A36,RIC8B,LGI2,TMLHE,ROBO1,RORB,PCMTD2,CCDC102B,NEK11,ATP8B4,PRR5L,LRRK2,WLS,ZNF568,RYR3,TRAPPC13,AP1AR,SAFB,SEMA6D,CSRNP3,ATXN2,LRRTM4,TNFRSF19,SUPT20H,KIF27,TRA2B,SGK1,ZFP30,ITSN1,SH3GL3,ARX,DOCK10,NTNG1,FBXO11,FNDC3A,SYBU,SEC31A,NUBPL,SLA,PPP4R3A,BTBD3,SLC6A1,RAB3GAP1,CCDC88A,SLC12A2,SLC14A1,SLC20A2,ATF7IP,ZFP1,SMARCD3,RCOR3,ANKRD36,RIMS1,MBD5,KIF13A,ZNF415,SNRPN,PALLD,TMCC1,UNC80,USP33,FAM219A,SON,WDTC1,MYT1L,ZCCHC24,KDM3A,HECW1,SPP1,NPAS3,TAB2,ITPRID2,SAMSN1,ERBIN,ELOVL4,SEPT8,RGL1,SULF2,GSE1,NECAB1,SYT11,FGD4,RHBDL3,ARHGEF9,VPS13A,ADAMTS17,SYPL1,SYT1,COBL,SYT4,ANKRD12,CAMSAP2,ADGRL3,AGTPBP1,TBCEL,KLHL4,ANO4,EHBP1,SATB2,TCF7L2,ZEB1,WASHC4,PCDHB10,SLC19A3,PCDHB7,PCDHB4,PUM2,GPRIN3,FRYL,TEX15,SIK3,SIRT1,ACTR6,ASXL3,PDSS1,RUNDC3B,PPIL6,DCBLD1,ANKRD20A2,ANO5,SSBP2,TTTY15,TUBB2A,TMEFF2,UBE3A,UBTF,GORASP1,CCDC14,TBC1D15,VSNL1,ZNF781,RICTOR,XRCC4,PCDH20,ZFP37,ZBTB14,ZIC2,ZNF28,KCNT2,FMN2,FSTL5,ZNF184,UPF3A,ZNF225,LRP8,EVI5,RNF103,SCG2,WIPF2,MPPE1,PARP11,AMN1,RTN4,JMJD1C,ZNF248,RNF170,SSPN,KLHDC1,FXR1,IFT88,NETO1,CBLN2,SLC4A10" MicroRNA hsa-miR-582-5p:mirSVR_highEffct hsa-miR-582-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.80E-207 1.57E-203 3.15E-204 2.90E-203 482 1847 "TKTL1,ARID1A,CSMD3,NDRG2,ADAR,ADD3,AXIN2,ERMN,GRAMD1B,AP2A2,KLHL13,KCTD16,OSBPL8,LRRC7,ALCAM,PCDH10,FAM135A,ANK1,MAP4K3,PPFIA1,APC,UPRT,ALS2,BCAS1,SHTN1,LGR5,AQP4,MIER1,TMEFF1,CAPRIN2,ASPH,ZBTB10,RASL11B,ATM,EIF4G3,ATP2B1,B3GALT2,N4BP2L1,DPY19L3,BMPR1B,NAE1,IL33,CACNA1D,CACNA1E,CACNB2,KALRN,PTBP2,SLC25A14,CAST,CH25H,SPAG9,RUNX1T1,USP6,DGKI,CD81,CDH2,ZMYM4,LGI1,MAGI1,CDO1,CCPG1,CFL2,ADGRG1,SRSF11,CHM,CHN2,CASC2,SYNPR,CNOT8,NDST3,PLAA,PPT2,NMT2,C4orf33,CNN3,CNR1,AKAP6,COL9A1,SLC4A8,ABI3BP,RCHY1,COX4I1,CHD1L,FAM171B,PREPL,CREM,ANKRD44,GDA,CS,MICAL2,VCAN,SOCS5,DZIP3,CTH,GREB1,PUM1,USP6NL,DOCK4,TOX,PHF19,ZFYVE16,LIN54,KIAA0586,MAML1,DGKG,DAPK1,TOMM20,PABPC5,BRINP1,ZNF804A,ZEB2,ZC3H11A,GSDME,PLPPR4,SNAP91,SV2B,SPOCK3,GRIN3A,DMD,NR1D2,DPP6,ACOT8,DTNA,DNAJB6,ABCC9,GOLT1B,E2F5,EDNRA,ATL1,RASGRP1,FRY,YAF2,PHF20L1,APH1A,KMT5B,EIF4G2,PLEKHA1,ELAVL3,EPB41L2,EPHA5,SRRM1,EPS8,MRPL37,ETV1,RCSD1,ADGRV1,CLVS1,NSRP1,ZNF461,WAC,ACSL4,SCML2,GORAB,MED12L,FGF12,FGR,POLK,SUCO,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,FLT1,SGIP1,COQ5,HVCN1,STAMBP,ATP6V1H,STAU2,B3GAT1,ABLIM2,OGA,FYB1,DKK3,GABRA1,GABRA2,CHL1,NCKAP1,IQGAP2,ZNF559,GART,GATM,SULT1C4,CYP46A1,HPGDS,GLI2,GLRB,GLS,MSL3,MAP7D2,GNAL,GNAO1,FERMT2,GOLGB1,ADGRA3,GPR17,LPAR4,GPR34,EML4,GRIA2,GRIA4,GRID1,GRIK2,NR3C1,PRDM5,GRM5,RNF165,PTPN5,LINC01551,AP4S1,SOX21,PSIP1,GUCY1B1,ARHGAP36,ELOVL5,HMGB1,HMGCR,HNF4G,ZDHHC15,NEGR1,ZIC5,RBPJ,INPP5B,INSM1,LRRTM3,ITGAV,KCNC1,KCNC2,KCNJ3,KCNMA1,KIF5C,KLC1,PAXBP1,FGFBP3,ARHGAP12,NCOA7,SMAD1,PIK3AP1,MAP2,MAP6,MARK1,SYT9,MEIS1,MIA2,POC1B,MITF,MMP16,ZNF680,NRBP2,SCG3,MTTP,MYO6,MYO9A,NAP1L1,NF1,NFE2L2,NOVA1,NPPA,HCN1,OPHN1,GPR137C,GLIPR1L2,PCSK1,PCSK5,PRTG,PDE4A,PDGFRA,GPR85,BEST3,NALCN,PIK3C2A,ZNF655,FAM218A,CCSER2,SNX10,RETREG1,XRN1,MTRF1L,TRHDE,STRN3,LRP12,SCHIP1,EPB41L4B,SH3KBP1,POU3F2,PRKACB,CEP41,PRKCZ,MAPK9,MAPK10,GRAMD1C,HYDIN,MASP1,RELN,CNNM2,SIDT1,MDGA2,CNTLN,BDNF-AS,MTMR10,PTHLH,PTK2,EML5,PEX5,CEP97,TMEM255A,FAT4,FAM184A,NWD1,RASGRF1,RBBP6,KHDRBS2,REV3L,GTDC1,RGS7,TTLL7,RLBP1,SLC25A36,NUDT11,PBRM1,ZFHX4,ZNF532,KLHDC8A,CARF,ROBO2,TMEM100,SPIN3,ATP8B4,RPL38,MAP6D1,LRRK2,LGR4,ABCA11P,NCBP3,SEMA6D,LRFN5,LRRTM4,ELMOD1,FOXRED1,SFPQ,ZFP30,ITSN1,SH3GL3,ARX,AMBRA1,FBXO11,R3HDM2,CNKSR2,WDR37,ZNF365,SLC1A6,FAM81A,BTBD3,SLC6A8,RAB3GAP1,ARHGEF40,SHANK2,SLC12A2,SLC20A2,GKAP1,SMARCA4,CDK5RAP2,SMARCE1,LIMCH1,SNAP25,KIF13A,ZNF415,SNRPN,MYO16,UNC80,MYT1L,TRERF1,SOX5,BDP1,KDM3A,GLT8D1,ZNF423,KIF1B,TSPYL2,NPAS3,SPART,C11orf87,CLASP2,TROVE2,CAMTA2,COLGALT2,MESP1,SST,EPB41L3,ZC4H2,LARP4,SS18,ERBIN,SEPT8,DIP2A,ADHFE1,SULF2,ZC3H4,ABCC8,SYNE2,NUDT10,PLCB1,SYPL1,C12orf76,ANKRD12,DDHD2,TAF9,CAMSAP2,FAM208A,ADGRL3,AGTPBP1,ANO4,TCF4,TCF7L2,TCF12,WASHC4,SYNE1,PUM2,USP32P1,FRYL,TEX15,DICER1,SIRT1,CRB1,SLC44A1,ACTR6,TLL2,RIMBP2,CSMD1,C5orf64,KAT6B,NPL,TPM4,TRIO,TSN,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE3A,UGT8,SLAIN1,ZNF709,P2RY12,ZNF781,WRN,CLDND1,RICTOR,ETNPPL,PCDH20,ZIC1,KCNT2,TRIM9,ZNF540,FTSJ1,EMSY,PRDM2,RGMA,ADAMTS9,PCDH15,NAV3,KCNAB1,FAM47E,DNAH10,FAM13C,FZD3,RTN4,PAK5,HNRNPA3,PHTF2,FBXO36,CASC15,ADAMTSL3,JMJD1C,TRAM2-AS1,ZNF248,VANGL2,SSPN,FRMD6,NETO1,FAM198A" MicroRNA hsa-miR-330-3p:mirSVR_highEffct hsa-miR-330-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.69E-203 3.76E-199 6.26E-200 5.77E-199 480 1871 "ACADM,ASIC2,CLK4,KLHL32,CCDC85A,GALNT13,ADD3,UNC5A,RNF150,DPY19L2P4,SLC44A5,ZNF608,ALAD,SMIM17,ARHGAP20,PCDH10,GPRASP2,AMPH,OGT,DPP10,LCORL,MAP4K3,GPAM,CACHD1,API5,LGR5,MADD,IGDCC4,ARNTL,CADPS,CDK13,ASPH,ZBTB10,RASL11B,TMEM108,ATP2B1,ATP2B2,ZNF583,SLC2A11,NOL4,BACH1,ADGRB3,BBS2,KSR1,DST,FUBP1,SCAPER,JAZF1,MYRF,IL33,CALM1,PTBP2,TRIM41,SLC25A14,VXN,VSTM2A,CAST,CBR1,KRIT1,CERS5,USP6,USP2,INA,C1orf52,MAGI1,CDO1,TIGD7,CCPG1,CIART,SRSF11,CHN2,JAM2,SLIT2,NRXN3,CLCN3,TJP2,MAP4K4,CNN3,ARMC8,COL4A5,BTF3L4,ABI3BP,ACBD5,MYRIP,CNRIP1,CPS1,CREM,NCOR1,GDA,ARHGEF10,OSBPL3,CSNK1G3,APPL1,NRSN1,DCAF4,DOCK4,GPRASP1,TOX,ZFYVE16,ZNF337,LIN54,KCTD8,MAML1,GIT2,YTHDC1,MYEF2,ELMO1,HP1BP3,FBXL5,KIAA0319,CEP170,BLOC1S6,RHOBTB1,SMG7,SPOCK3,SGSM2,RABGAP1L,WDR20,FAM107B,KIF19,KBTBD11,DLX1,DMD,DMTF1,DPP6,DRD1,DRP2,RCAN1,DNAJB6,DYRK1A,DNM1L,EDN1,EDNRA,ANKRD46,EFNA3,RBM12,PHF20L1,APH1A,MBNL2,SORBS3,ELAVL2,ING4,TUBD1,VPS13B,EPB41L1,EPB41L2,RCAN2,EPHA5,GPHN,RABEPK,EPS8,EFS,F5,FAM198B,ACSL4,EFEMP1,FCGR3A,PPP1R1B,FGF12,FGFR1,FHL1,SUCO,FOXG1,IP6K2,AGAP2,SYNCRIP,SEMA4D,ANKFY1,SLC37A3,JKAMP,TMEM107,USP16,ARFGAP2,ATP2C1,ERGIC3,CELF1,ST6GALNAC3,NSG1,STAU2,NRG3,TVP23A,ZNF512,FYB1,HBS1L,ERAP1,ATP8A2,KIAA1841,GCNT2,SULT1C4,GGT7,KIRREL3,TCERG1,COPS8,GLDC,DBF4,GLYR1,GPR75,TOX3,MSL3,KDM2B,LUZP2,KCNMB4,GNAO1,GPM6A,TDRKH,FUT10,LILRA1,GPR37,GRB10,GRID1,GRM5,LINC00839,GUCY1A2,WIF1,KLF12,MIER3,HPSE2,HNRNPK,HSF2,LRRC75A,IRF8,NKD1,RBPJ,USP54,SCIN,ZNF678,KCNA4,KCNK2,CREG2,KIF2A,KLRC2,KLC1,INSYN2,LIG4,LMO2,SYTL4,ARHGAP12,NCOA7,ASPRV1,PACRG,MAP4,MARK1,MAT2A,MBD1,MBNL1,LDLRAD3,LRP1B,MKLN1,AFDN,XRRA1,MN1,CD200,COL28A1,CCDC80,MSI1,BLOC1S2,MSRA,SCG3,RSPO2,MYBPC1,MYH3,NAP1L1,NELL1,NF1,SLCO1C1,NPTX2,NTRK3,PAH,SNTG1,PCDH9,PCMT1,PDE1A,PDE1B,SERPINI1,PIK3R1,SNX10,PLP1,PRIMPOL,PMP22,STRN3,LRP12,PRRX1,ING3,SH3KBP1,POU3F2,MINDY2,PPM1B,CRLS1,PPP2R5C,PPP2R5E,PPP3CB,KANSL1,PRKACB,CEP41,PRKCZ,MAPK9,MAPK10,HYDIN,DIRAS2,VPS13C,LRRC49,GDPD2,PSMD13,ELOVL2,PTK2,ZIK1,PTPRB,OCIAD1,C1orf109,PEX5,MARCH1,CEP97,USP47,PLEKHB2,RAD51D,RASGRF2,ARID4A,VEPH1,ZDHHC14,GTDC1,RFX4,RGS10,NUDT11,PBRM1,RPRD1A,ZFHX4,CCDC82,RAVER2,ROBO1,ELP2,RPL15,MCMBP,ADAL,LGR4,KCNIP3,KCNIP2,ZNF568,RXRG,CCDC112,FAM192A,RMI1,S100B,SALL1,MAPK12,SEMA6D,SATB1,SCN2A,SCN3A,LRRTM4,FAM19A1,LINC00461,SCP2,SLC30A10,GALNT10,NLGN4Y,KIF16B,SHC4,CHD9,FNDC3A,ST6GAL1,CNKSR2,SYBU,ZNF365,SLC1A6,DHX30,RUFY2,CCDC88A,NAPB,SLC20A2,COA1,MBD5,PDZRN3,USP33,SON,KDM3A,SP4,ENKUR,KDM4C,ZNF423,ZC3H13,KIF1B,SPART,SRPK2,ATP10B,TROVE2,POGZ,SSTR1,EPB41L3,ERBIN,STAU1,ZSCAN29,DIP2A,SULF2,ZFR2,SYNE2,COBL,TAC1,TAC3,TACC1,DNMBP,UNC5D,FBXW11,TBX15,ATMIN,TCF4,TCF7L2,TRIM2,WASHC4,CLASP1,DOCK9,SLC19A3,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,SIRT1,ITGB3BP,TGFBR3,GZF1,TJP1,TK2,ASXL3,BHLHB9,ZFP91,FAM124A,KAT6B,CABIN1,TNR,C9orf85,SYNPO2,ELP5,TRPC3,TRPS1,ZMYND8,TSC1,CLHC1,CLEC2L,AMOT,SLAIN1,PITPNB,PLEKHH2,USP1,MEAF6,VLDLR,KLC2,CFAP298,ZIC3,ZNF711,MICU3,KCNT2,MKRN3,ZBTB16,ANKS1B,EMSY,PRTFDC1,LRP8,LINC02210,PRDM8,RNF103,TUBA1A,ADAMTS9,MDH1B,PCDH15,ITM2C,SLC17A6,PLSCR4,FAM13C,FZD3,DOCK8,CERS6,ACTR3B,RNF170,MSRB3,SLC4A10,FAM198A" MicroRNA hsa-miR-425:mirSVR_lowEffct hsa-miR-425:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.45E-202 2.50E-198 3.57E-199 3.29E-198 474 1831 "SDE2,ABAT,ACADM,CLK4,KDM5D,SLC25A25,PSMG3-AS1,ADD3,AXIN2,ERMN,PWWP2A,KIAA1211,ADRA1D,MTUS1,KCTD16,HACE1,TXNDC16,AK2,ZNF578,C1QTNF3,LRRC7,ALCAM,ARHGAP20,FAM135A,GPRASP2,SYT13,ZFAT,USP28,SUGT1P4-STRA6LP-CCDC180,PKP4,KCNAB2,MAGEE2,DGKD,ALS2,SHROOM2,ZFYVE28,ARNTL,CADPS,MARK4,NUMB,ALDH4A1,ATP2A2,NOL4,DPY19L3,ATP6V0A1,BACH1,BCL7A,NRP2,KSR1,DST,SYNJ2,CA8,CACNA1B,CACNB4,CALB1,THSD7A,SHISA7,MTMR7,INA,AIFM1,SYNGR3,CDC25B,TIGD7,CCPG1,CLGN,FOXN3,CASC2,NDST3,LSMEM2,RAB28,ZFYVE9,KIAA1549L,CLCN4,TPP1,NMT2,C4orf33,SLC25A27,LETMD1,AKAP5,ABI3BP,RCHY1,SMARCAL1,HAPLN1,RNF14,ANKRD44,GDA,TRIM69,SNCAIP,SEC24C,CSNK1G3,ATRNL1,PDE4DIP,PLXNA4,FAM169A,CTH,CTNND1,CTNND2,NRSN1,PUM1,HDAC9,TOX,ZFYVE16,CENPL,MATR3,MAML1,PABPC5,BRINP1,DNAL1,DBN1,ARMCX4,ELMSAN1,C8orf34,TIAM2,FBXL5,DDX46,ALKBH8,SRGAP3,WDR20,ZNF582-AS1,DLG2,DMD,HS3ST4,NR1D2,DPP6,DPYSL2,DRD1,RCAN1,ARRDC4,DTNA,DNAJB6,ABCC9,E2F6,EDN1,ANKRD46,FRY,SIDT2,SH3GLB1,PHF20L1,EGR3,DCTN4,USPL1,VPS13B,SEZ6,EPHA5,RABEPK,EPS8,RTN3,MRVI1,ABCA8,RPS6KC1,ATP8A1,TOMM40L,KAT8,SEC24B,PRKAG2,UBE2E3,CAP2,IP6K2,FLT1,POMT1,USP16,PDLIM5,ZNF605,ST6GALNAC3,STAU2,PNMA2,TMEM151A,AP4B1,ZNF512,PHYHIPL,DKK3,GABRA1,GABRA5,GABRG2,GAD2,HBS1L,ARPP21,ZNF274,ERAP1,SYT17,DISC1,CPLX2,NEU3,ALDH1L1,ARFIP1,GFAP,TOX3,TNRC6A,HTATSF1,INSM2,LUZP2,DCLK2,GOLGB1,ADGRA3,GPD2,FUT10,LPAR4,GPR34,NUDT21,GRIA1,DIDO1,GRIA4,GRIK2,NR3C1,GRM1,GRM8,BVES,SOX21,HLF,SYNPO,TCEAL6,DHX35,IRF8,FAM95B1,SOWAHA,RBPJ,DOCK7,KIAA1755,IL12A,LRRTM3,LRRTM1,ITGAM,JAK2,OLFM3,KCNB1,KCND1,KCNJ3,KCNJ10,KCNJ11,KCNMA1,KLRC2,KLRC3,IPO5,LAMP2,LIMS1,PAXBP1,NCOA7,C2orf80,SMAD1,SMAD9,MAN2A2,MBNL1,MEIS2,POC1B,AFF1,AFDN,XRRA1,MMP16,MN1,MRPL42,SESN3,ADAM22,PTOV1,LAYN,MYO5A,MYO9A,NAP1L1,NAP1L2,NCAM1,NEUROD1,NFE2L2,NPY,DNHD1,ODF2,GPR88,CHAMP1,OLR1,OPCML,OPHN1,P2RX7,TREM2,GLIPR1L2,PAX6,PCDH8,PCDH9,PDE1A,PDE3A,PDE4D,PDE1B,PDGFRA,PDPK1,GNG2,BEST3,PFKFB2,CDK14,GDAP1L1,NALCN,ANLN,SNX10,RETREG1,HMGCLL1,LRP12,PPARA,PPP2R5E,PPP3CB,PRKACB,ANKHD1,PLPPR1,MTMR10,PTHLH,PTPRG,FAM120C,PTPRZ1,RAD17,FAM66C,FAT4,ARID4A,VEPH1,ZDHHC14,FIGN,RFX3,RGS7,ZNF532,TMLHE,C12orf49,RAVER2,PNMA8A,ROBO1,CCDC25,CCDC102B,ATP8B4,PTGR2,SYNDIG1,WLS,ZNF568,AP1AR,RMI1,ATXN2,LRRTM4,SCN8A,ZFP2,TRIM46,SUPT20H,COPZ1,HSPA4L,SCAF8,FERMT1,CPEB3,MYO18A,NTNG1,FNDC3A,FHOD3,ZNF365,PEX26,EPN2,SMTN,WDR47,FAM214B,SLC6A8,SLC9A5,SLC12A4,TMEM132D,ELMO2,EFHD1,SLC20A2,ATF7IP,SLCO1A2,LGI3,ZKSCAN3,SORCS3,SMARCD3,RIMS1,SNCA,KIF13A,LMBRD1,SCN3B,DOP1A,SON,MYT1L,NMNAT2,KDM4C,TEX2,IDI2-AS1,PEG10,ZBTB43,RBM26,NPAS3,SPART,C11orf87,SRPK2,ATP10B,CAMTA2,EPB41L3,ZC4H2,ST5,INKA2,MAPK8IP3,STAU1,ZSCAN29,TTBK2,ADHFE1,KANK1,SULF2,SEPT3,NECAB1,SYT11,PRRC2C,ZFR2,NUDT10,SYPL1,ATP11A,TAF9,FAM208A,UNC5D,AGTPBP1,TBCEL,ANO4,EHBP1,ACSL6,DMXL2,TPCN2,TCF12,WDR7,RALYL,TEK,PMS2CL,SIRT1,LEFTY2,AP4E1,HHIP,TIAM1,HEY1,ACTR6,TLR4,ERCC6L2,LRRC8A,C5orf64,TNR,RASD2,TPM1,NPL,TPM3,ZNF384,RGMB,ZNF346,PDSS1,RUNDC3B,TTC3,SGK3,RPL7L1,GORASP1,UGT8,SLAIN1,PLEKHH2,VSNL1,RBFOX3,RICTOR,SLC13A3,ETNPPL,SF1,ZNF24,TRIM9,ZNF45,AGMO,ZNF70,TCEAL7,SPIRE1,PLPPR5,DHX33,EMSY,PRDM10,TMEM178A,CAB39L,WIPF2,PLSCR4,C12orf4,GOPC,SMIM8,JMJD1C,NHSL1,ZDHHC20,NETO2,NETO1,ZNF30" MicroRNA hsa-miR-30e:mirSVR_highEffct hsa-miR-30e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.61E-198 3.71E-194 4.64E-195 4.27E-194 489 1991 "RALGAPA1,CLK4,ABHD6,ARID1A,CSMD3,GALNT16,GALNT13,RNF157,ADD1,BRAP,CDC7,SORCS1,ERMN,KIAA1211,LRFN2,ADRB2,AP2A1,AP1B1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,ALS2,CACHD1,VAT1L,USP37,PPP4R4,TMEM263,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B1,ATP2B2,ATP2B3,DPY19L3,ADGRB3,MPDZ,SEC11C,NRP2,BID,KSR1,DST,MTMR2,BSN,CACNB2,CALB2,CABP7,CAMK2D,SLC25A14,CARS,RUNX1T1,CBS,SLC5A11,USP2,SYNGR3,DGKI,SEPT7,ZBED1,LGI1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,ZBED5,NDST3,KMT2C,NRXN3,FAM189A2,QKI,MAP4K4,NIPBL,ARHGEF6,CNR1,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,ZFP28,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,PHACTR3,PHF14,GREB1,CTNND2,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TOX,PHF19,TBC1D5,MATR3,KCTD8,MAML1,TOMM20,YTHDC1,JAKMIP2,C8orf34,CEP170,MAGI2,BLOC1S6,ALKBH8,PLPPR4,SACS,SPOCK3,RABGAP1L,WDR20,RAB39B,DMD,CPEB2,DMTF1,SLC12A6,PDCD6IP,DTNB,MAMLD1,DYRK1A,DNM1L,ABCC9,GOLT1B,EDIL3,WDPCP,FAM135B,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,EML1,DCTN4,EN2,EPB41,EPB41L2,LRRC17,KCNMB2,STX2,DENND4A,CDHR1,RCSD1,EXTL2,ABCA8,FABP7,SH3YL1,SCML2,ATP8A1,GORAB,POLR1B,AMOTL2,PRKAG2,POLK,SCARA3,UBE2E3,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,DCTN2,SORBS1,SMC2,UFM1,FAM49B,ATP6V1H,KHDRBS3,DACH2,NSG1,MSANTD4,AP4B1,NRG3,OGA,ZMAT1,STAG2,CHL1,GABRB1,TRAF3IP2,ILDR2,HBS1L,JPH4,GALR1,IP6K3,ERAP1,ATP8A2,KIAA1841,MYOZ2,GATM,GCNT2,SULT1C4,PCDH17,PPARGC1A,MALT1,TTBK1,GLDC,DBF4,GLRB,GLS,TNRC6A,GNAO1,GNAS,ADGRA3,PRUNE2,GPM6A,TDRKH,GPR12,GPR19,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,GRM3,GRM5,CIT,FAM19A2,GUCY1B1,CELF3,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,NEGR1,SMAP1,RAB41,C2orf72,SOWAHA,DOCK7,ZNF678,DIPK1A,LRRTM3,LRRTM1,JAK1,KCNA2,KCNJ3,KCNMA1,STXBP5,LAMP2,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,MBD1,MBP,SYT9,CHIC1,MEIS1,MEIS2,MID1,PPM1L,MITF,MOBP,ERICH3,MRPL42,JAKMIP3,ADAM22,PABPC1L2A,NAP1L2,NAP1L3,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,OMG,OPHN1,ZNF827,PCDH9,PDE4D,PIRT,PDGFRA,GPR85,OLA1,PIK3CD,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,SLC22A23,LAMA1,ANKHD1,ELOVL2,PXK,TMEM260,PTPN13,PPP2R3C,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,ERI2,FIGN,RGS7,TTLL7,RNF220,RPRD1A,ZFHX4,SETD5,EXD2,RAVER2,CARF,GSTCD,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,LINC00461,SLC30A10,SUPT20H,ITSN1,FRMPD1,ARX,KIF16B,CPEB3,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,PAAF1,ZNF365,FAM81A,KANSL3,PKNOX2,SLC6A9,SPHKAP,TET1,ZFP1,SORCS3,SMARCE1,RCOR3,TTC17,ANKRD36,LIMCH1,SNRPN,TMCC1,MYO16,SON,BDP1,DOK5,KDM3A,SP4,HECW1,BEX1,KIF1B,RBM26,NPAS3,SPART,CLASP2,SSTR1,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,NEK4,RGL1,ADHFE1,STXBP1,SYPL1,COBL,SYT4,DDHD2,CAMTA1,MCF2L,ADGRL3,ANO4,DMXL2,SATB2,USP22,CLASP1,WDR7,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,CRB1,AP4E1,SLC44A1,GZF1,ACTR6,TLL2,R3HDM1,CSMD1,TP53BP2,TPD52L2,TPM1,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,ZMYND8,DCBLD1,ANKRD20A2,ANO5,SSBP2,RFTN2,RPL7L1,PITPNB,PLEKHH2,CCDC14,MICAL1,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,ZNF23,MICU3,AGMO,MKRN3,CELF4,ZBTB38,SPIRE1,ZFAND5,CA10,SLC30A4,PMEPA1,MAP3K12,CSDE1,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,PAK5,SMIM8,HNRNPA3,PHTF2,CASC15,CERS6,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-3120:mirSVR_highEffct hsa-miR-3120:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.36E-197 4.70E-193 5.22E-194 4.81E-193 485 1969 "RALGAPA1,ABCF1,KCNH8,ARID1A,PWWP2A,RNF150,ESYT2,SLC44A5,ZNF608,INTS2,KLHL13,PCDH19,AGT,HACE1,OSBPL1A,TBC1D14,TAOK1,ADGRF5,C1QTNF3,ALCAM,ARHGAP20,PCDH10,FAM135A,GPRASP2,AMPD2,OGT,CDC42BPA,ANK1,ANK2,ANK3,PPFIA1,APC,GPAM,API5,APP,SHTN1,PDXK,IGDCC4,ZFYVE28,PDE8B,NUMB,TMEM108,ATP1B3,RNF182,CFLAR,DST,SYNJ1,ARHGEF7,MYRF,CA8,CACNB2,KALRN,CAMK2D,RUNX1T1,NFS1,LDB2,KRIT1,INA,SEPT7,ZBED1,CDC42,MAGI1,SRSF11,CHN2,TAOK2,KMT2C,NRXN3,PLAA,COG1,CLTA,CLTC,TJP2,QKI,HECTD1,NIPBL,CNTFR,IQCK,ARMC8,AKAP6,BTF3L4,MAGED1,TBPL1,AHCTF1,ZFP28,IGDCC3,HS3ST5,SLC35F1,CPS1,FAM171B,CREM,HAPLN1,NCOR1,LRIG1,MICAL2,CSNK1G3,ATRNL1,VAC14-AS1,FAM169A,GREB1,CTNND2,ZSCAN23,EDRF1,CX3CR1,CCDC144A,DOCK4,HDAC9,ARHGAP32,TCAF1,ARHGAP24,HDAC4,TOX,KIAA0586,TOMM20,PITPNC1,SPATA2,ELMSAN1,DNAJC6,C8orf34,ZEB2,MYEF2,C2CD2L,ZC3H11A,RHOBTB1,SMG7,SACS,SRGAP3,G3BP2,DMD,DYNC1I1,DNM2,CPEB2,DOCK2,DPP6,DRD1,DTNA,ECM2,FAM78B,DNAJB6,DYRK1A,ABCC5,AASDH,FAM135B,HIPK3,RBM12,EGFR,KMT5B,ABI2,IRAK4,ELAVL2,EMX2,COQ7,EPHA5,EPS8,SPEG,TMEM74,ETV1,TUBB3,EFEMP1,CHST15,TESK2,MED12L,KIAA1109,FGFR1,FGFR3,TMEM164,MAD2L2,FHL1,POLK,SYNCRIP,IQCG,FLT1,SLC37A3,SYT3,NBEA,SORBS1,TMEM107,SMC2,HVCN1,UFM1,ATP2C1,CELF1,CSPG5,SARAF,TBR1,AP4B1,ZNF512,ZMAT1,GABRA1,GABRA2,GABRG2,CAB39,HBS1L,DISC1,GART,KIAA1841,MYOZ2,IGSF5,GDF9,ADAM28,MMADHC,GJB1,COPS8,SPIN1,GLI2,TOX3,MSL3,HTATSF1,GNAO1,GOLGB1,GPD2,TDRKH,B4GALNT4,STON1,LPAR4,PCLO,CNTRL,GRIA1,GRIA2,GRIA4,PLCD4,GRIK2,NR3C1,GRM5,CIT,LINC00839,RNF165,MFSD2A,RABL2A,GYG1,PTGDR2,HMGB1,HNF4G,HNRNPK,SMAP1,HTR2A,ZNF546,INPP1,ZNF385B,NME9,ITGAV,JAK2,OLFM3,KCNH2,KCNJ5,KCNK1,KCNK2,KLRC2,KLC1,IPO5,STXBP5,LAMP2,STMN1,VWA5A,HECTD2,PACRG,SMAD1,PIK3AP1,LOC100128239,MAP2,MAPT,MARK3,MBNL1,MDFI,LRP1B,MKLN1,AFF1,ERICH3,ZNF680,MSR1,MTTP,MYO9A,HNRNPM,NCAM2,OTOGL,NOVA1,NRCAM,HCN1,NTRK2,CLDN11,GLIPR1L2,SNTG1,PCDH9,PDE1C,PDE3B,PDE4B,ENPP2,GNG2,PFKFB2,OLA1,CDK14,SERPINE2,NALCN,PIK3C2A,NOMO2,PCDH18,SMIM7,PRRX1,EPB41L4B,NXPH1,PPM1B,PTPA,PPP2R5E,PPP3CB,PRKACB,PRKCB,PKN2,PRKCZ,CNNM2,SIDT1,SNRK,MDGA2,WDR25,PIGG,MTMR10,OCIAD1,PTPRD,C1orf109,PEX5,PPP2R3C,TMEM255A,USP47,RAP1GDS1,RASGRF1,ARID4A,RBBP6,RADX,RDX,ZMAT4,FIGN,SEC61A2,SLC25A36,NUDT11,ZFHX4,LGI2,ZNF532,SETD5,C12orf49,ELP2,CCDC102B,CNTNAP3,LGR4,KCNIP3,KCNIP1,AP1AR,RMI1,AMER2,SALL1,SCN3A,FNIP1,SLC30A10,SELL,COPZ1,KIF21A,SH3GL3,DOCK10,HKDC1,MAGI3,FBXO11,FNDC3A,CNKSR2,NLGN1,DHX30,RUFY2,CCDC88A,SLC11A1,CDK5RAP2,SMARCE1,SNCA,PALLD,RBM34,SON,PDZD2,MYT1L,TRERF1,SOX3,PEG10,SPTAN1,KIF1B,ZBTB43,C11orf87,ITPRID2,SAMSN1,SMOC1,ERBIN,ST5,MPRIP,SEPT8,CEP68,SEPT3,GSE1,KLHL7,SYT11,FGD4,VPS13A,SYP,SYPL1,PJA1,DDHD2,CAMSAP2,ADGRL3,TBCEL,TBL1X,ANO4,SATB2,TCF7L2,TPCN2,USP22,PCDHGA11,SYNE1,SLC19A3,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,VWCE,ZFPM2,C18orf54,LEFTY2,AP4E1,ARL10,THRA,GZF1,BHLHB9,ERCC6L2,TMPO,CSMD1,PIK3R5,TRO,TSN,CA14,ANKRD20A2,TSC1,SSBP2,TST,SGK3,CADM1,PLEKHH2,P2RY12,WRN,KLC2,CLDND1,RICTOR,ZIC1,ZIC3,ZNF708,ELFN1,PLPP4,NDRG4,MKRN3,ZNF142,ZBTB38,TMEM237,ZNF184,SPIRE1,ZFAND5,SMARCAD1,CA10,EMSY,PRDM2,ADAMTS9,TMEM178A,CIAPIN1,PCDH15,NAV3,KCNAB1,ITM2C,MPPE1,SLC17A6,MRPL47,DOCK8,UBE3B,KAT6A,PHTF2,ADAMTSL3,RSPRY1,ZNF248,NETO1,RNF146,FAM198A,JPH3" MicroRNA hsa-miR-301b:mirSVR_lowEffct hsa-miR-301b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-196 6.18E-193 6.18E-194 5.69E-193 466 1817 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,PWWP2A,PTCHD1,PCDH19,KCTD16,CC2D2A,AK2,ADGRF5,LRRC7,BCAR3,ABCD2,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,PHF12,PPFIA2,EPB41L5,TNRC6C,SHTN1,IGDCC4,ASCL1,ATP1A2,SLC4A4,ATP2A2,MTMR9,B3GALT2,DOCK11,KSR1,BMPR1B,CDK5R1,FUBP1,LINC00906,MTMR3,SGCE,NIPA1,LDLRAD4,CAMK2D,CAMK2G,TRIM41,CANX,VSTM2A,USP2,CBFA2T2,REPS2,CDC42,MAGI1,NOG,CACNA2D2,SRSF11,CASC2,MS4A7,SYNPR,CLCN4,COG1,FBXO7,C4orf33,QKI,HECTD1,CNN3,CNR1,IQCK,SLC25A27,AKAP5,SLC4A7,SLC4A8,TBPL1,BAG4,ZNF521,CREB5,HAPLN1,FEZ2,MICAL2,SUSD5,SIPA1L1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,LIN54,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,CTIF,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KIAA0319,MAGI2,KLHL3,SNAP91,SV2B,G3BP2,FAM107B,KBTBD11,DLG2,GRIN3A,USP3,DNAH9,MED12,NR1D2,DNM2,SLC25A18,DRP2,GNE,DTNA,ECM2,E2F5,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPB41,EPHA5,GPHN,CEP85L,CDHR1,KATNAL1,WAC,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FDFT1,FECH,OLFM1,TMEM164,AMOTL2,PRKAG2,CAMSAP1,POLK,MEX3B,FOXG1,PCYOX1,ANKFY1,NOP56,STAU2,KBTBD12,DKK3,GAB1,GABRA3,ZNF44,GABRG1,CAB39,FAM120B,ZMYND11,GALC,RAPGEF6,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,TOX3,CBX1,FERMT2,GPT2,ADGRA3,ATF7,MCHR1,GPER1,CECR2,PCLO,GRIA4,GRIK1,NR3C1,GRM2,LINC01089,TMEM25,KAT7,LINC01551,SOX21,ADAMTS6,GUCY1A1,MAP4K5,ATOH8,FAM222A,CELF3,RASSF8,HAS2,HPS5,FRMD3,MIER3,HLF,SCRG1,SYNPO,AGFG1,IGF1,NIM1K,DOCK7,IL11RA,LRRTM3,NME9,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNK1,KCNN2,KIF5C,KIT,C2orf80,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,LRP1B,MEIS1,AFF1,AFDN,WDR49,MOBP,ZNF680,ADAM22,SCG3,MYCN,MYH6,MYO9A,PABPC1L2A,NAP1L2,NCAM1,IDNK,NF1,NOS1,NOVA1,NPTX1,NPTX2,HCN1,NUMA1,TBC1D25,OGDH,OLR1,OPCML,KCNK10,GLIPR1L2,PDE1A,PDE4B,PDE4D,GNG2,CYTL1,PFKFB3,PIK3C2A,TMIE,PIK3R1,ZFYVE21,FAM216A,PLP1,PDZRN4,STRN3,SCHIP1,ING3,FAT3,POU6F1,MED1,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,SNRK,MDGA2,ZIK1,PTPRD,PTPRE,TMEM231,PPP2R3C,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,RBBP6,BSDC1,GTDC1,FIGN,RFX3,RFX5,RIC8B,RNASEL,CCDC82,EXD2,ROBO1,RORB,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,PRR5L,LGR4,YJEFN3,RYR3,ZNF331,FAM192A,SATB1,ATXN1,SCN4B,SCN8A,LINC00461,SELL,GALNT10,FOXRED1,HSPA4L,PUF60,ITSN1,CPEB3,DOCK10,AMBRA1,FNDC3A,R3HDM2,SLITRK3,NUBPL,FAM81A,SLC12A2,SLCO1A2,CPEB4,MAST1,SMARCD3,RCOR3,RIMS1,CABCOCO1,SNRPN,SON,SOX2,KIF21B,FNBP1,KDM3A,ZSWIM8,EMC1,KDM4C,TSPYL2,RBM26,LMO3,EPB41L3,LARP4,STAU1,SEPT8,DIP2A,ADHFE1,STXBP1,AJAP1,MLC1,VAMP1,SYT1,SLC37A2,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,PDLIM2,AGTPBP1,TBCEL,TMEM136,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,TMEM151B,PCDHB7,USP32P1,FRYL,CRB1,ZFP91,HEY2,TMOD1,DAAM2,RIMBP2,PARD3,RBFOX2,NPL,NR2C2,ZNF346,SMUG1,TRPS1,ANO5,HIRA,EIF4ENIF1,UBE3A,LINC00689,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,CLDND1,XRCC4,PCDH20,ZNF24,FMN2,SLC26A10,CELF4,SPIRE1,WNK1,EMSY,SLC38A1,CSDE1,EVI5,LINC02210,PRDM10,RNF103,PCDH15,NAV3,SNX27,FIP1L1,FAM47E,SLC17A6,PDSS2,FAM13C,AMN1,DOCK8,RTN4,PHTF2,FBXO36,GJC2,CASC15,CERS6,FAM219B,JMJD1C,ZNF248,RNF170,PIANP,NETO2,SOCS4,SLC4A10,CPNE4,JPH3" MicroRNA hsa-miR-30c:mirSVR_highEffct hsa-miR-30c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.92E-196 1.08E-192 9.78E-194 9.01E-193 482 1948 "RALGAPA1,CLK4,ABHD6,ARID1A,CSMD3,GALNT16,CCDC85A,GALNT13,RNF157,ADD1,BRAP,CDC7,SORCS1,ERMN,KIAA1211,LRFN2,ADRB2,AP2A1,AP1B1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,C1QTNF3,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,UPRT,ALS2,CACHD1,VAT1L,USP37,PPP4R4,TMEM263,TMEFF1,ZFYVE28,CADPS,TMEM108,ATM,STX16,ATP2B1,ATP2B2,DPY19L3,ADGRB3,MPDZ,SEC11C,NRP2,BID,KSR1,DST,SYNJ2,SCAPER,MTMR2,CACNB2,CALB2,CAMK2D,SLC25A14,CARS,CBS,SLC5A11,USP2,SYNGR3,DGKI,SEPT7,ZBED1,LGI1,L3MBTL4,LARGE1,MAGI1,DLGAP1,TIGD7,CFL2,CHN1,MS4A7,ZBED5,NDST3,KMT2C,NRXN3,FAM189A2,QKI,MAP4K4,NIPBL,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,ZFP28,SLC35F1,PNKD,CLOCK,SLC32A1,GDA,SEC24C,OSBPL3,PDE4DIP,DZIP3,PHF14,CTNND2,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TOX,TBC1D5,MATR3,KCTD8,MAML1,TOMM20,SPATA2,YTHDC1,JAKMIP2,C8orf34,MYEF2,CEP170,MAGI2,BLOC1S6,ALKBH8,PLPPR4,SACS,SPOCK3,RABGAP1L,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,MAMLD1,DYRK1A,DNM1L,ABCC9,GOLT1B,EDIL3,WDPCP,FAM135B,YAF2,CELSR3,FAM13A,MBNL2,EGR3,ASB3,TENM1,PCOLCE2,TMEM35A,EML1,DCTN4,EN2,EPB41,EPB41L2,LRRC17,KCNMB2,STX2,DENND4A,CDHR1,RCSD1,EXTL2,ABCA8,FABP7,SH3YL1,SCML2,ATP8A1,AMOTL2,SCARA3,UBE2E3,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,SGIP1,SORBS1,UFM1,ATP6V1H,KHDRBS3,DACH2,NSG1,STAU2,MSANTD4,SARAF,NRG3,OGA,ZMAT1,STAG2,CHL1,GABRB1,TRAF3IP2,HBS1L,JPH4,GALR1,IP6K3,ERAP1,ATP8A2,KIAA1841,MYOZ2,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLRB,GLS,TNRC6A,GNAO1,GNAS,ADGRA3,PRUNE2,TDRKH,GPR19,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,GRM3,GRM5,CIT,FAM19A2,GUCY1B1,CELF3,RASSF8,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,ZDHHC15,NEGR1,SMAP1,RAB41,C2orf72,SOWAHA,ZIC5,DOCK7,ZNF678,DIPK1A,LRRTM3,LRRTM1,JAK1,JAK2,KCND2,KCNJ3,STXBP5,KTN1,CAMK2N2,INSYN2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,SYT9,CHIC1,MEIS2,MID1,PPM1L,MITF,ERICH3,MRPL42,JAKMIP3,ADAM22,PABPC1L2A,NAP1L2,NAP1L3,NEFM,NEK1,NF1,SLC11A2,SMIM11A,NTRK3,NUCB2,OCRL,OMG,PCDH9,PCSK1,PDE4D,PIRT,PDGFRA,CDK14,PIK3CD,SNX10,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R5E,PRKACB,CEP41,RAB39A,EPDR1,SLC26A11,VPS13C,SLC22A23,LAMA1,ANKHD1,ELOVL2,PXK,TMEM260,PTPN13,PTPRZ1,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,ERI2,FIGN,RGS7,TTLL7,SEC61A2,RNF220,RPRD1A,SETD5,EXD2,RAVER2,CARF,PCMTD2,LRRK2,CNTNAP3,ABCA11P,RTN1,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,LINC00461,SLC30A10,SUPT20H,ITSN1,FRMPD1,ARX,KIF16B,CPEB3,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,PAAF1,FAM81A,KANSL3,PKNOX2,SLC6A9,SPHKAP,TET1,ZFP1,SORCS3,SMARCE1,RCOR3,TTC17,LIMCH1,TMCC1,MYO16,SON,BDP1,DOK5,KDM3A,SP4,HECW1,BEX1,KIF1B,RBM26,NPAS3,SPART,TAB2,CLASP2,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,ELOVL4,NEK4,RGL1,SEPT3,STXBP1,SYPL1,COBL,SYT4,TACR1,DDHD2,CAMTA1,MCF2L,ADGRL3,ANO4,DMXL2,SATB2,USP22,CLASP1,WDR7,SYNE1,RALYL,USP32P1,SLC35G2,SIRT1,TMEM121,CRB1,SLC44A1,GZF1,ACTR6,TLL2,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,ZMYND8,DCBLD1,ANKRD20A2,SSBP2,RFTN2,PRR18,TMEFF2,PITPNB,CCDC14,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,LYPD6,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,CA10,SLC30A4,MAP3K12,CSDE1,STOX2,RNF103,ADAMTS9,HPS4,NAV3,FIP1L1,PARP11,AMN1,FZD3,DOCK8,MARCH8,PAK5,HNRNPA3,PHTF2,CERS6,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-342-3p:mirSVR_lowEffct hsa-miR-342-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-196 2.75E-192 2.29E-193 2.11E-192 473 1879 "CPNE2,KCNH8,SYS1,TKTL1,CSMD2,ARID1A,GPRIN1,KLHL32,ADCY2,AP2A1,TBC1D14,AK2,LRRC7,SPOP,PCDH10,BBOX1,GOLGA7B,FAM135A,PITPNM2,AMPD3,ANK2,CCDC146,MAP4K3,CNIH2,SUGT1P4-STRA6LP-CCDC180,DGKZ,UPRT,NT5C3B,TNRC6C,SHROOM2,SEMA4G,MADD,ZSCAN18,NCOA1,STX16,ZNF583,CADM3,N4BP2L1,ATP6V0A1,TTLL9,ADGRB2,LINC00847,BCL2L2,KSR1,BMP7,SYNJ2,AP1M1,BSN,WASF1,IL33,CACNA1B,CACNA1D,DDR1,CACNB4,CALB1,DIRAS1,CAMK2D,SPAG9,RUNX1T1,ZNF501,MTMR7,SLC16A4,SCARB1,ENTPD6,CDC27,CDC42,CDH8,CDH10,LGI1,CRLF1,CFL2,SRSF11,CHRM1,CASC2,MS4A7,SYNPR,NRXN3,STOML1,VAX2,C4orf33,QKI,NIPBL,CNR1,AKAP7,LETMD1,MAGED1,COX4I1,TOGARAM2,HS3ST5,CDC42BPB,RBM39,SH2B1,CS,TENM4,SEC24C,FEZ2,OSBPL3,ATRNL1,IPCEF1,SIPA1L1,SOCS5,ERC2,PHF14,CTH,NRSN1,PUM1,RIMS2,NOS1AP,DOCK4,GAPVD1,TBC1D5,IST1,DGKB,ARMCX4,ZBTB24,ELMO1,KIAA0319,POM121,SMG7,SNAP91,SV2B,WDR20,DLG3,RAB39B,DNAH9,MED12,NR1D2,DOCK2,DMTF1,DPH1,DTNA,ECM2,FAM78B,TOM1,DNAJB6,ABCC9,AASDH,EBF1,HEYL,KLHL5,TMTC1,OPTN,APH1A,KMT5B,ABI2,ASB3,IRAK4,ELAVL2,PCOLCE2,COQ7,EPHA5,ANKRD13B,STX2,SPEG,MRPL10,DNAJC27,ANKMY1,RASL12,ADGRV1,F5,REEP2,WAC,FABP7,ACSL4,TUBB3,CHST15,FGF12,CAMSAP1,CAP2,FOXM1,SEMA6C,FLNC,TMEM107,PDLIM5,ZNF605,CELF1,DACH2,CGREF1,TBR1,DOT1L,ABLIM2,STAG2,MEGF10,HRASLS5,CHL1,GABRB1,GABRB3,SALL3,NEK6,IQGAP2,ZNF559,DISC1,SEPT9,ATP8A2,KIAA1841,DNER,NEU3,PCDH17,GK,ZNF276,CRCP,RNPS1,DBF4,GLYR1,GLRB,TNRC6A,ZNF638,GNAS,ZNF782,PRUNE2,ATF7,DIPK1C,TDRKH,FUT10,CCDC184,GPR37,GRB10,GRIA4,GRID1,GRIK1,CACFD1,ADAMTS8,ATE1,PRDM5,RNF165,GSTM5,MFSD2A,PSIP1,FAM107A,RNFT2,TMEM179,FAM222A,PADI2,NXPH2,GPR45,TNFAIP8L3,HNRNPK,NEGR1,OPALIN,HSPA1L,MSL1,FAM95B1,C5orf24,INPP5B,KCNA2,KCNC2,KCNJ3,KCNJ10,KHK,LINC00634,KIT,IPO5,PAXBP1,SYTL4,FGFBP3,MAPT,LYPLAL1,MARK3,MBD1,SCAMP5,AFDN,MSI1,MSR1,MSRA,MT1M,THYN1,DDX25,MTTP,MYO5A,MYO7A,NASP,NBL1,NHLH1,VWA2,NOVA2,SMIM11A,HCN1,SETD4,ODF2,GPR88,ZDHHC22,SNTG1,PBX1,PCSK1,PDE4D,PIRT,PFKFB2,CDK14,DUSP26,SERPINE2,PIK3CD,ZNF655,FAM216A,PCDH18,LRP12,SH3KBP1,PPARA,PPP2R5E,PPP3CB,RASGEF1B,PKIA,PRKCB,EPDR1,MASP1,CNNM2,WBP1L,LAMA1,GON4L,WDR25,CNTLN,PTPRN,FAM120C,TMEM231,PLEKHB2,SUSD4,ENOX1,RBBP6,RADX,ZDHHC14,FIGN,RFX4,RGS3,RGS4,ARHGEF10L,RIC8B,NUDT11,RNASEL,GSTCD,PCMTD2,RPE,UEVLD,ZC3H14,PRR5L,ACER3,LRRK2,PAQR6,ATAT1,RXRA,ZNF331,AP1AR,DGLUCY,LINC00461,ASIC4,TRIM46,ITSN1,FAM102A,FERMT1,KIF16B,HKDC1,FBXO11,NLGN1,DZIP1,SLC1A7,EPN2,FAM214B,SLC6A1,SLC6A8,ELMO2,BTBD7,SLCO1A2,SLC22A4,TET1,CPEB4,ZFP1,CDK5RAP2,IFT122,MBD5,CMTR2,SNRPN,SCN3B,SON,TRERF1,NMNAT2,SPP1,ZNF423,SPTAN1,KIF1B,IQSEC2,SPART,NFASC,LMO3,C11orf87,SRPK2,TAB2,ATP10B,TROVE2,POGZ,ITPRID2,STOX1,LRRC4,SEPT8,ADHFE1,SEPT3,MLC1,COBL,ATP11A,ANKRD12,CAMTA1,TAL1,IQCE,VWA3A,DMXL2,KIAA0930,CUX2,TCF7L2,WASHC4,WDR7,SYNE1,AKNA,PUM2,TNS2,ARHGAP9,CRB1,ZNF106,BHLHB9,FAM124A,R3HDM1,CSMD1,SEZ6L,TPM3,DOK6,NEIL2,NUTM2A,TMPRSS5,TSN,SSBP2,TMEFF2,HEPACAM,CADM1,RPL7L1,AMOT,UBTF,PITPNB,PLEKHH2,USP1,CCDC14,TBC1D15,NSD2,XRCC4,ZFP37,CRB2,LYPD6,ZBTB38,TMEM237,EML6,PLPPR5,MEIS3,DHX33,WNK1,CADM2,PRDM2,NT5M,SLC38A1,RGMA,CSDE1,RNF103,VPS35L,SEMA3B,PPP1R3F,CAB39L,SLC17A6,EPM2A,FZD3,PAK5,KAT6A,ACTR3B,JMJD1C,NHSL1,NETO2,NETO1,RNF146,SLC4A10,JPH3" MicroRNA hsa-miR-200c:mirSVR_highEffct hsa-miR-200c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.73E-194 4.91E-190 3.77E-191 3.48E-190 462 1812 "RALGAPA1,ABAT,KCNH8,ACHE,CLK4,SYS1,ARID1A,XKR4,CSMD3,SLITRK1,ADD3,ERMN,PWWP2A,PTCHD1,NLGN4X,SLC24A4,MTUS1,GPR158,CC2D2A,HFM1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,LCORL,MAP4K3,PPFIA1,PKP4,PARG,ALS2,VAT1L,SHROOM2,CDC14B,IGDCC4,CAPRIN2,ASPH,NUMB,STX16,ATP2A2,ATP2B1,DPY19L3,ADGRB3,MPDZ,PROM1,CDK5R1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,OSGIN2,IL33,MMD2,CA8,CACNB2,CACNB4,THSD7A,PTBP2,CAST,SPAG9,CDC27,ZMYM4,NOG,CFL2,COPB2,CHM,CHN2,NRXN1,TJP2,FAM19A5,DNAJB5,QKI,CNN3,CNTFR,AKAP7,SLC25A27,BTF3L4,COL9A2,SLC4A7,SLC4A8,GAL3ST1,IFFO1,BAG4,HINFP,GDA,CS,CSF1,SEC24C,CSF3R,FEZ2,FEZ1,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,CTNND2,USP6NL,CCDC144A,CYBB,DOCK4,GPRASP1,ARHGAP24,DCAF8,LIN54,MATR3,KCTD8,TMEM170A,GIT2,SIRPA,DCC,ELMSAN1,ZEB2,MYEF2,RUSC2,BLOC1S6,PLPPR4,WDR20,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DYNC1I1,DTNA,MAMLD1,DNAJB6,DNM1L,ABCC9,CNNM1,TMTC1,FSD1L,YAF2,EGR3,GOLGA7,EIF4G2,ELAVL2,EML1,PAN3,MTSS1L,EPS8,EXTL2,ACSL4,TAOK3,DLC1,TESK2,FER,POLR1B,FGF12,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXG1,FOXF2,ATP13A4,ANKFY1,SGIP1,NOP56,JKAMP,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,AP4B1,OGA,FYN,CAB39,ARPP21,ZNF274,SIGLEC8,GART,KIAA1841,GATM,MSTN,SESN1,FREM1,MALT1,COPS8,GLS,TNRC6A,INSM2,FERMT2,GPM6A,CECR2,GRB10,GRIA2,GRIA4,NR3C1,FAM19A2,PSIP1,MAP4K5,WIF1,RASSF8,HPS5,ARHGAP19,MIER3,HLF,HMGB1,HNRNPK,NEGR1,AGFG1,ZNF181,TJAP1,IGSF1,IL12A,LRRTM3,KCND2,KCNJ3,KCNJ16,KIF2A,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LDLRAD3,LRP1B,MEST,MITF,ERICH3,MRPL42,MYCN,NAP1L2,OTOGL,CNOT4,NOVA1,NPTX1,SMIM11A,HCN1,NTRK2,NUCB2,IGSF11,CHAMP1,P2RY1,PCDH8,PCSK2,PRTG,PDE4B,GPR85,GNG2,PENK,PFKFB2,PFKP,CDK14,SERPINI1,NALCN,ANLN,FAM218A,A2ML1,SNX10,XRN1,KCTD15,PLCL1,HMGCLL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,NXPH1,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SIDT1,SNRK,CNTLN,PTCH1,PLPPR1,BDNF-AS,MTMR10,PTHLH,TMEM260,PTPN13,OCIAD1,PTPRD,EML5,PTPRZ1,ZSCAN2,FAT4,OXR1,ARID4A,RADX,MSANTD2,RDX,RET,REV3L,ERI2,GTDC1,FIGN,RLBP1,SEC61A2,NUDT11,RNASEL,RPRD1A,CCDC82,ZNF532,RAVER2,CARF,ROBO1,ROBO2,RORB,CCDC102B,ARMH4,FBXW7,ACER3,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,AMER2,SEMA6D,SCN8A,SCP2,SUPT20H,KIF21A,ITSN1,SHC4,AMBRA1,FNDC3A,R3HDM2,SEC31A,ANKRD6,ZNF365,FAM81A,SLC6A1,KDM4D,SLC8A3,SLC12A2,SLC14A1,SLC15A2,SLIT1,ZNF667,MAST1,SORCS3,MYH15,SMARCE1,SNAP25,MBD5,KIF13A,SNRPN,TMCC1,UNC80,FAM219A,PDZD2,SOX1,SOX2,ZCCHC24,KIF21B,BDP1,DOK5,KDM3A,ENKUR,CAND2,KDM4C,ZNF423,KIF1B,SPART,C11orf87,CLASP2,TROVE2,ITPRID2,ZNF302,SS18,MPRIP,SEPT8,RGL1,PHLDB1,KANK1,SYNE2,VAMP1,ARHGEF9,VPS13A,SYT1,ANKRD28,CAMSAP2,ADGRL3,TMEM136,SATB2,ZEB1,WASHC4,CLASP1,RALYL,AKNA,ARHGEF12,PUM2,SLC35G2,FRYL,CCDC173,TEX15,RNF216P1,TEK,ZFPM2,TGFBR3,TLL2,ERCC6L2,CSMD1,TPD52,TRIO,RUNDC3B,AMACR,RFTN2,TUBB2A,TMEFF2,FAM155A,UGT8,SLAIN1,VLDLR,TBC1D15,VSNL1,RBFOX3,WIPF1,CLIP2,CLDND1,GUSBP1,XRCC4,ZIC3,TRIM9,MKRN3,LYPD6,TCEAL7,ZBTB38,REEP1,TFIP11,SMARCAD1,SYNC,EMSY,EVI5,TMEM178A,CIAPIN1,NAV3,FAM13C,PAK5,KAT6A,PHTF2,NLRP3,RNF170,KLHDC1,FXR1,IFT88,SLC4A10,GAN" MicroRNA hsa-miR-2053:mirSVR_highEffct hsa-miR-2053:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.31E-193 5.23E-189 3.74E-190 3.44E-189 477 1943 "RALGAPA1,ABAT,ACTN2,CSMD2,FMNL2,KLHL32,SLITRK1,CCDC85A,TMCC3,CDC7,ERMN,PWWP2A,ESYT2,PTCHD1,KIDINS220,BEND6,DPY19L2P4,WDR35,C1QTNF3,PCDH10,FAM135A,DPP10,LRCH2,SEMA7A,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,ALS2,DDO,LRRC4C,SHTN1,LGR5,CDC14B,CASK,LINC00173,CDK13,ASPA,ASPH,ZBTB10,NCOA1,SLC4A4,STX16,ATP2B1,RNF182,B3GALT2,DPY19L3,MPDZ,SYNJ1,SYNJ2,FUBP1,NAE1,IL33,CACNB4,THSD7A,CALM1,PTBP2,CAMK2D,CANX,RUNX1T1,NFS1,PRC1,CLDN10,RGN,C1orf52,L3MBTL4,CCPG1,NUMBL,RCBTB2,SRSF11,CHGB,CHM,CASC2,B4GALT6,IGFBP7-AS1,PLAA,CLCN4,ABCG2,FAM19A5,C4orf33,NIPBL,CNGA3,CNR1,AKAP7,AKAP6,COL4A5,SLC4A7,SLC4A8,ABI3BP,RTTN,ZFP28,HS3ST5,CP,CLOCK,PREPL,HINFP,ANKRD44,CLIP3,CS,FEZ2,ARHGEF10,CSNK1G3,DZIP3,PNPLA8,CFAP61,CTNND2,PUM1,CYBB,DOCK4,HDAC9,GAPVD1,RIPOR2,FRMPD4,ZFYVE16,DGKB,PABPC5,JAKMIP2,C8orf34,ZEB2,ZBTB24,FBXL5,KLHL3,BLOC1S6,ZC3H11A,GSDME,SV2B,SPOCK3,SRGAP3,SGSM2,RAB39B,DMD,DNM1,DOCK2,SLC12A6,ABI1,DTNA,ECM2,DNAJB6,DNM1L,E2F5,EDNRA,EDNRB,HIPK3,RASGRP1,SEMA3D,TMTC1,FSD1L,PHF20L1,MBNL2,LPAR6,GOLGA7,IRAK4,ELAVL2,PLEKHA1,ELAVL4,MRNIP,EML1,STARD3NL,CALCRL,PAN3,RCAN2,EPHA5,GPHN,SRRM1,DENND4A,NCALD,CEP85L,SIRPB1,CLVS1,ZNF461,WAC,FABP7,ACSL4,ZIC4,CEP78,ZSCAN30,GORAB,FER,KIAA1109,FGFR3,FHL1,POLK,JKAMP,SMC2,UFM1,PDLIM5,USP21,ATP2C1,ERGIC3,CELF1,ST6GALNAC3,STAU2,NRG3,PHYHIPL,GABRA1,GABRA2,HRASLS5,CHL1,GAD2,AHCYL1,JPH4,ARPP21,ZNF274,ERAP1,DISC1,WASF3,SULT1C4,MSTN,ADAM28,PPARGC1A,MALT1,LYVE1,DHRS4,GLYR1,GLRB,LUZP2,GNAS,GPM6B,STON1,LPAR4,PCLO,CNTRL,GRIA2,GRM1,GRM3,GRM7,FAM19A2,BVES,PSIP1,GUCY1B1,IRAK3,HPS5,ZHX1,NXPH2,MIER3,ELOVL5,GABARAPL2,ICA1,IDH3A,LIX1,DIPK1A,ZNF385B,LRRTM3,NME9,SLC35G1,KCND2,KCNK1,KTN1,LAMP2,INSYN2,LIG4,HECTD2,GPR155,LOC100128239,MAP2,MARK1,MBD1,MBNL1,SYT9,MDM4,LRP1B,MEF2C,MEST,POC1B,MMP16,MSR1,MYO9A,NAP1L1,NAP1L3,NFE2L2,ALDH1L2,CNOT4,NOVA1,LRIT2,PCBP3,SLC11A2,NTRK2,NUMA1,SETD4,OGG1,OLR1,SNTG1,PBX1,ETFRF1,PCDH9,PCSK5,PDE4B,PDE4D,PDGFRA,PFKP,SERPINI1,FAM218A,RETREG1,GPSM2,PLCL1,PCDH18,HMGCLL1,PMP2,PMP22,TRHDE,SCHIP1,ING3,SLC36A4,PILRA,PPP2R2B,PPP2R5E,PPP3CA,PPP3CB,RANBP3L,RAB39A,MAPK4,HYDIN,SAMD9,VPS13C,SYTL2,GON4L,PSMD13,PIGG,CNTLN,PLPPR1,MTMR10,PTPRB,PTPRO,PTPRZ1,PPP2R3C,TMEM255A,RAD51D,RAD52,FAM66C,ZNF793,FAT4,SUSD4,ZNF493,DBX2,RADX,KHDRBS2,RDX,GTDC1,RNASE1,RPRD1A,ZNF532,CARF,TMEM206,CCDC102B,RPE65,BAALC,GLDN,LRRK2,LGR4,PTGR2,ABCA11P,CLIP1,TRAPPC13,TMEM156,MIR124-2HG,LRFN5,SCN3A,LINC00461,FNIP1,SLC30A10,SGK1,NTNG1,MAGI3,CHD9,FHOD3,SLITRK3,NLGN1,ZNF365,PPP4R3A,BTBD3,EPN2,RUFY2,SEPHS1,SLC12A2,SLC22A4,CPEB4,ZFP1,ZNF667,SNCA,LMBRD1,SNRPN,PDZRN3,UNC80,TRERF1,SP2,EMC1,HECW1,UHRF1BP1L,SPP1,ZC3H13,RBM26,C11orf87,SRPK2,TAB2,PBLD,CLASP2,SAMSN1,EPB41L3,LARP4,NKAIN2,SS18,KLHL7,FGD4,PRRC2C,VPS13A,ATP11A,PJA1,EXOC7,CAMSAP2,FAM208A,ADGRL3,TBCEL,FBXW11,KLHL4,EHBP1,SATB2,CUX2,TCF7L2,ZEB1,WASHC4,SZT2,SYNE1,PCDHB4,PUM2,TEX15,SIK3,ZNF34,HHIP,SLC44A1,TIAM1,TLR4,ZFP91,HEY2,CSMD1,TPD52,RGMB,SYNPO2,STXBP4,DCBLD1,ANKRD20A2,RFTN2,TTC3,SGK3,SLAIN1,PLEKHH2,TOM1L2,WNT7A,ZNF711,MICU3,ZNF540,TCEAL7,FSTL5,ZNF184,SPIRE1,SMARCAD1,ZNF225,MFF,PRDM2,DNALI1,LRP8,EVI5,PRDM10,SEMA3B,NAV3,PPP1R3F,PLSCR4,PDSS2,FAM13C,KAT6A,PHTF2,ADAMTSL3,TIGD6,NETO1,SLC4A10,GAN,SENP7" MicroRNA hsa-miR-130a:mirSVR_lowEffct hsa-miR-130a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-192 8.15E-189 5.40E-190 4.98E-189 452 1744 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,ERMN,PWWP2A,AK2,ADGRF5,LRRC7,BCAR3,ABCD2,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,MYH7B,PPFIA2,APBB2,EPB41L5,TNRC6C,SHTN1,LGR5,ASCL1,ATP1A2,SLC4A4,ATP2A2,ZNF582,MTMR9,B3GALT2,DOCK11,KSR1,BMPR1B,SGCE,NIPA1,GPC2,LDLRAD4,CALB1,CAMK2D,CAMK2G,TRIM41,CANX,VSTM2A,RUNX1T1,USP2,ENTPD6,SEPT7,REPS2,CDC42,CDH2,MAGI1,NOG,SRSF11,MS4A7,CLCN4,COG1,FBXO7,C4orf33,QKI,HECTD1,RAB26,FHL5,IQCK,SLC25A27,SLC4A7,SLC4A8,BAG4,ZNF521,CREB5,HAPLN1,FEZ2,MICAL2,SIPA1L1,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,ELMO1,MAGI2,KLHL3,SNAP91,SV2B,NTM,G3BP2,FAM107B,DLG2,DLG3,GRIN3A,NYAP1,USP3,DNAH9,MED12,NR1D2,DNM2,SLC12A6,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPHA5,RABEPK,SLC43A2,CEP85L,TLR7,KATNAL1,WAC,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FKTN,FECH,OLFM1,AMOTL2,SCARA3,MEX3B,FOXG1,PCYOX1,ANKFY1,JKAMP,STAU2,DKK3,GABRA3,ZNF44,GABRG1,CAB39,ZMYND11,ZNF274,IQGAP2,C15orf41,DNER,TUBGCP4,AHDC1,PCDH17,PPARGC1A,DBF4,TOX3,GPT2,ADGRA3,ATF7,GPR12,MCHR1,GPER1,CECR2,PCLO,GRIA2,GRIA4,GRIK1,NR3C1,GRM2,LINC01089,KAT7,LINC01551,SOX21,GUCY1A1,MAP4K5,FAM222A,CELF3,HAS2,HPS5,FRMD3,MIER3,HLF,SCRG1,SYNPO,AGBL5,AGFG1,SHISA6,CELF5,IGF1,NIM1K,ZNF385B,LRRTM3,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNK1,KCNN2,KCNQ3,KIF5C,KIT,IPO5,C2orf80,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,LRP1B,KITLG,AFF1,WDR49,ZNF680,ADAM22,MYH6,PABPC1L2A,NAP1L2,IDNK,NELL2,NFYA,NOS1,NOVA1,NPTX1,NPTX2,HCN1,NUMA1,TBC1D25,OGDH,OPA1,OPCML,KCNK10,PDE1A,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,FAM216A,PDZRN4,STRN3,ING3,FAT3,POU6F1,PKIA,HYDIN,RELN,VPS13C,DEF8,MDGA2,ZIK1,PTPRD,PTPRZ1,PPP2R3C,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,ARID4A,RBBP6,BSDC1,GTDC1,FIGN,RFX3,RFX5,UBR7,RGS3,RIC8B,RNASEL,EXD2,ROBO1,RORB,TMEM206,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,GLDN,PRR5L,ACER3,LGR4,YJEFN3,RYR3,ZNF331,SALL1,SATB1,ATXN1,SCN4B,SCN8A,TNFRSF19,SELL,GALNT10,HSPA4L,PUF60,ITSN1,CPEB3,AMBRA1,FNDC3A,R3HDM2,NUBPL,WDR37,RAB3GAP1,SLC12A2,CPEB4,GKAP1,MAST1,RCOR3,RIMS1,CABCOCO1,SNRPN,UNC80,KDM4B,SON,SOX2,KIF21B,FNBP1,KDM3A,ZSWIM8,EMC1,KDM4C,PEG10,ZBTB43,TSPYL2,RBM26,C11orf87,ATP10B,EPB41L3,LARP4,SEPT8,DIP2A,KANK1,STXBP1,AJAP1,MLC1,FGD4,VAMP1,C3orf70,SYT1,ANKRD28,SYT4,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,PDLIM2,AGTPBP1,TBCEL,TMEM136,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,PHF24,TMEM151B,PCDHB7,ARHGEF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,CYB561A3,TGFBR3,ZFP91,HEY2,RIMBP2,PARD3,RBFOX2,RASD2,NPL,RGMB,NR2C2,SMUG1,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,LINC00689,BCL2L13,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,RICTOR,XRCC4,PCDH20,ZNF24,FMN2,SLC26A10,LYPD6,CELF4,SPIRE1,SMARCAD1,SYNC,UPF3A,EMSY,EVI5,LINC02210,NAV3,SNX27,KCNAB1,FAM47E,WNK3,SLC17A6,PDSS2,FAM13C,DOCK8,FBXO36,CASC15,FAM219B,RNF170,TTC7A,PIANP,NETO2,SOCS4,SLC4A10,CPNE4,JPH3" MicroRNA hsa-miR-590-3p:PITA hsa-miR-590-3p:PITA_TOP PITA 1.54E-192 8.64E-189 5.40E-190 4.98E-189 417 1477 "CPNE2,ABAT,CLK4,FMNL2,KLHL32,CCDC85A,GALNT13,ADD1,ADD3,AXIN2,CDC7,USP31,ADRB2,ZNF608,INTS2,PCDH19,HACE1,TBC1D14,OSBPL8,LRRC7,ALCAM,LTBP4,FAM135A,OGT,ANK3,EP400,MAP4K3,USP28,APAF1,APC,GAS7,CACHD1,USP37,AQP4,TMEM263,TMEFF1,ARHGAP5,ZBTB10,NCOA1,SLC4A4,ATP2B1,MTMR9,NOL4,DOCK11,NAE1,BTK,JAZF1,FOXK1,CALB1,CALM1,PTBP2,SPAG9,MAP7,INA,C1orf52,CDC42,MAGI1,CLGN,CFL2,SOCS6,CHM,KMT2C,RAB33A,PLAA,QKI,NIPBL,CNR1,AKAP6,AKAP5,RCHY1,AHCTF1,CLOCK,RBM39,CREB5,OSBPL3,CNTNAP2,SLITRK5,PPP1R16B,UBXN2A,PHF14,CTNND2,RIMS2,RUBCN,KIAA0408,DOCK4,DCAF8,FRMPD4,LONRF1,DGKB,PABPC5,DBT,PITPNC1,DNAJC6,C8orf34,MYEF2,TIAM2,CEP170,KLHL3,DDX46,RHOBTB1,WDR20,ARNT2,DLG2,DLX1,RAB39B,NR1D2,CPEB2,ARRDC4,DNAJB6,ABCC5,E2F5,SNX29,EDN1,HIPK3,RASGRP1,FSD1L,OPTN,RBM12,YAF2,SH3GLB1,MBNL2,KMT5B,GOLGA7,KCTD3,EIF5,ELAVL2,PLEKHA1,EML1,EPB41L1,GPHN,ETV1,RTN3,EYA1,WAC,ACSL4,PTK2B,ATP8A1,FKTN,SEC24B,FOXG1,CAP2,FOXF2,SYNCRIP,ZMYND15,FOXO3,ANKFY1,SGIP1,AFF2,AKAP3,TACC2,UFM1,NPTN,KHDRBS3,FYN,PHYHIPL,STAG2,GABRA4,GABRG2,CAB39,RAPGEF6,IP6K3,ATP8A2,WASF3,MSTN,ARFIP1,PCDH17,PPARGC1A,GK,TCERG1,RNPS1,SPIN1,GLRB,PCDH11X,KDM2B,FERMT2,GOLGB1,NUDT21,TUBA1C,GRIA2,GRIA4,FAM19A2,COQ10A,KAT7,SOX21,GUCY1A1,FAM222A,WIF1,HAS2,ARHGAP19,ATXN2L,KLF12,MIER3,HLF,ELOVL5,GABARAPL2,AGBL5,HNRNPK,AGFG1,SMAP1,C5orf24,BRINP3,LRRTM3,ITGAV,ITPKB,JAK2,SLC35G1,KCND2,KCNJ3,KCNMA1,KIF5C,STXBP5,KTN1,SMAD1,MAP2,MARK1,MBD1,MBNL1,CHIC1,MDM4,LRP1B,MEST,KITLG,AFF1,HS6ST3,MYCN,MYO6,NEXMIF,NAP1L1,NCAM2,ZC3H12B,NF1,SLCO1C1,NME4,IGSF11,CHAMP1,CNTN3,PCDH9,PCSK2,PDE4D,GNG2,PFKFB2,OLA1,SERPINE2,XRN1,PLP1,PURG,PMP2,TRHDE,STRN3,LRP12,EPB41L4B,FAT3,POU3F2,PPARA,MED1,PPP2R5E,CEP41,RAB39A,PKN2,SYTL2,CNTLN,UHRF1BP1,MTMR10,PTPRB,FAM120C,TMEM255A,USP47,ARID4A,DBX2,FEZF2,RDX,SLC6A15,RET,REV3L,UBR7,TTLL7,RIT2,SETD5,C12orf49,CARF,RPL15,ACER3,LRRK2,SOX8,CLIP1,SALL1,SEMA6D,SATB1,ATXN1,LRFN5,TNFRSF19,CASC3,SFPQ,TRA2B,SGK1,ZFP30,ITSN1,PPP1R9A,PPM1E,SHC4,CHD9,FBXO11,FNDC3A,R3HDM2,SLITRK3,NLGN1,CLSTN1,PPP4R3A,BTBD3,SLC6A1,SLC8A1,RAB3GAP1,CCDC88A,SLC12A2,SLC20A2,ATF7IP,TET1,CPEB4,SLN,GKAP1,RCOR3,RIMS1,SNAP25,ZCCHC24,SOX10,SOX11,KDM4C,ZC3H13,CDK19,TSPYL2,SPART,SRPK2,ATP10B,POGZ,SST,EPB41L3,LARP4,LRRC4,ERBIN,NXT2,STAU1,ELOVL4,SEPT8,KANK1,ARHGEF9,C3orf70,PLCB1,SYN2,SYPL1,ANKRD28,SYT4,ATP11A,CAMTA1,CAMSAP2,ADGRL3,AGTPBP1,ANO4,TBX15,TCEA1,WSCD1,TCF4,SATB2,CUX2,PSD3,PCDHB4,ARHGEF12,CRTC1,DICER1,SIRT1,ZFPM2,ITGB3BP,AP4E1,HHIP,AKTIP,SLC44A1,THRA,NACC2,RIMBP2,CSMD1,KAT6B,PDSS1,TRPC1,TRPS1,SGK3,FAM155A,EIF4ENIF1,FLRT2,USP1,MEAF6,TBC1D15,WIPF1,NSD2,CLDND1,XRCC4,ZNF28,KCNT2,CFAP52,FMN2,REEP1,TMEM237,WNK1,EMSY,CADM2,RNF103,SNX27,WNK3,SLC17A6,RGS7BP,PAK5,KAT6A,HNRNPA3,PHTF2,JMJD1C,MSRB3,RNF146,SOCS4,SENP7" MicroRNA hsa-miR-429:mirSVR_highEffct hsa-miR-429:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.94E-192 2.22E-188 1.30E-189 1.20E-188 470 1892 "SDE2,ABAT,KCNH8,ACHE,CLK4,SYS1,ARID1A,XKR4,CSMD3,FMNL2,SLITRK1,ADD3,CDC7,ERMN,PWWP2A,PTCHD1,NLGN4X,SLC24A4,MTUS1,GPR158,HFM1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,LCORL,MAP4K3,PPFIA1,PKP4,PARG,ALS2,VAT1L,SHROOM2,AQP4,CDC14B,IGDCC4,CAPRIN2,ASPH,NUMB,STX16,ATP2A2,ATP2B1,DPY19L3,MPDZ,PROM1,CDK5R1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,OSGIN2,IL33,MMD2,CA8,CACNB2,THSD7A,PTBP2,CAST,SPAG9,CD86,CDC27,CDC42,ZMYM4,NOG,CACNA2D2,CFL2,CHM,CHN2,NDST3,NRXN1,TJP2,FAM19A5,DNAJB5,QKI,CNN3,CNTFR,AKAP7,SLC25A27,BTF3L4,COL9A2,SLC4A7,SLC4A8,GAL3ST1,BAG4,HINFP,GDA,CS,CSF1,SEC24C,CSF3R,FEZ2,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,CTNND2,USP6NL,CCDC144A,DOCK4,GPRASP1,ARHGAP24,DCAF8,LIN54,MATR3,KCTD8,TMEM170A,GIT2,SIRPA,ELMSAN1,ZEB2,ZBTB24,MYEF2,RUSC2,BLOC1S6,PLPPR4,WDR20,ARNT2,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DYNC1I1,CPEB2,DTNA,MAMLD1,DNAJB6,ABCC9,ATL1,CNNM1,TMTC1,FSD1L,EGR3,GOLGA7,EIF4G2,ELAVL2,PAN3,MTSS1L,EPS8,ETV1,CLVS1,ACSL4,TAOK3,DLC1,TESK2,FER,POLR1B,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXG1,CAP2,FOXF2,ATP13A4,ANKFY1,SGIP1,NOP56,JKAMP,APOPT1,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,MSANTD4,OGA,FYN,CAB39,ARPP21,ZNF274,GART,KIAA1841,GATM,MSTN,SESN1,FREM1,GHR,MALT1,COPS8,GLS,TNRC6A,INSM2,FERMT2,GPM6A,CECR2,GRIA2,GRIA4,NR3C1,FAM19A2,PTPN5,PSIP1,MAP4K5,WIF1,RASSF8,HPS5,ARHGAP19,MIER3,HLF,HMGB1,HNRNPK,NEGR1,AGFG1,SHISA6,ZNF181,TJAP1,IGSF1,IL12A,BRINP3,LRRTM3,KCND2,KCNJ3,KCNJ16,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LDLRAD3,LRP1B,MEIS1,MEST,ERICH3,MRPL42,MYCN,NAP1L2,OTOGL,CNOT4,NOVA1,NPTX1,SLC11A2,SMIM11A,HCN1,NTRK2,NUCB2,IGSF11,CHAMP1,PCDH8,PCSK1,PCSK2,PRTG,PDE4B,GPR85,GNG2,PENK,SERPINE2,SERPINI1,NALCN,ANLN,FAM218A,A2ML1,SNX10,XRN1,KCTD15,PLCL1,HMGCLL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,NXPH1,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SIDT1,SNRK,PTCH1,PLPPR1,BDNF-AS,MTMR10,PTHLH,TMEM260,PTPN13,OCIAD1,PTPRD,EML5,PTPRZ1,ZSCAN2,FAT4,OXR1,ARID4A,RADX,MSANTD2,RDX,REV3L,ERI2,FIGN,RLBP1,SEC61A2,SLC25A36,NUDT11,RNASEL,RPRD1A,CCDC82,ZNF532,RAVER2,CARF,ROBO1,RORB,CCDC102B,RPE,ARMH4,FBXW7,KIAA0895L,ACER3,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,AMER2,SEMA6D,SCN8A,SCP2,ELMOD1,SUPT20H,KIF21A,ITSN1,SHC4,AMBRA1,FBXO11,FNDC3A,R3HDM2,SEC31A,ANKRD6,SLA,ZNF365,FAM81A,SLC6A1,KDM4D,SLC8A3,SLC12A2,SLC14A1,SLC15A2,SLIT1,ZNF667,SORCS3,MYH15,SMARCE1,SNAP25,MBD5,KIF13A,SNRPN,TMCC1,UNC80,FAM219A,PDZD2,SOX1,SOX2,ZCCHC24,KIF21B,BDP1,DOK5,ENKUR,CAND2,KDM4C,ZNF423,KIF1B,SPART,C11orf87,CLASP2,TROVE2,POGZ,ITPRID2,ZNF302,NKAIN2,MPRIP,SEPT8,RGL1,DIP2A,PHLDB1,KANK1,SYNE2,VAMP1,VPS13A,SYT1,ANKRD28,ANKRD12,CAMSAP2,ADGRL3,FBXW11,TMEM136,SATB2,ZEB1,WASHC4,CLASP1,RALYL,PCDHB9,AKNA,PUM2,GPRIN3,CCDC173,TEX15,RNF216P1,ZFPM2,TGFBR3,HEY1,ASXL3,TLL2,ERCC6L2,CSMD1,TRIO,RUNDC3B,AMACR,RFTN2,TUBB2A,TMEFF2,FAM155A,UGT8,SLAIN1,BCL2L13,VLDLR,TBC1D15,RBFOX3,WIPF1,CLIP2,GUSBP1,XPO1,XRCC4,ZIC3,ZNF711,ZNF23,TRIM9,MKRN3,LYPD6,TCEAL7,ZBTB38,REEP1,TFIP11,SMARCAD1,SYNC,PRDM2,PRTFDC1,EVI5,TMEM178A,NAV3,FAM13C,PAK5,KAT6A,PHTF2,NLRP3,TRAM2-AS1,ZNF248,RNF170,KLHDC1,FXR1,IFT88,SLC4A10,GAN" MicroRNA hsa-miR-410:mirSVR_highEffct hsa-miR-410:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.67E-192 3.19E-188 1.77E-189 1.63E-188 457 1789 "RALGAPA1,KCNH8,NCKAP5,ACTN1,ARID1A,SLC25A25,CSMD3,FMNL2,CCDC85A,ADCY8,AXIN2,SORCS1,GRAMD1B,UNC5A,PWWP2A,ADRA1B,KIDINS220,ZNF608,WDR35,TXNDC16,ADGRF5,C1QTNF3,LRRC7,BCAR3,ABCD2,GPRASP2,AMPH,LCORL,MAP4K3,PPFIA1,PARG,UPRT,GPAM,VAT1L,TNRC6C,SHTN1,MIER1,CASK,ARHGAP5,ASPH,NUMB,TMEM108,RNF182,CADM3,DPY19L3,ADGRB3,SEC11C,NRP2,BMPR1B,SYNJ2,BTK,JAZF1,C5,CA8,CALB1,KALRN,PTBP2,SLC25A14,RUNX1T1,ARHGEF25,CLDN10,CD86,SYNGR3,CDC27,CDH2,CDH10,LRRFIP1,MAGI1,NOG,CIART,SRSF11,CHM,CHN2,SYNPR,NDST3,NRXN3,CLTC,FAM19A5,QKI,NIPBL,TMEM155,CNN3,ARMC8,FAM149A,AKAP6,COL4A5,COL9A1,COL9A3,AHCTF1,RTTN,MYRIP,CREB5,HAPLN1,TRIM69,SNCAIP,OSBPL3,CSNK1G3,SUSD5,SOCS5,PHACTR3,PNPLA8,CTH,CFAP61,CTNND1,ST18,ZSCAN23,CCDC144A,BOC,FGFR1OP2,ARHGAP24,HDAC4,MATR3,DAPK1,IP6K1,PABPC5,DNAJC6,ZEB2,MYEF2,ZC3H11A,RHOBTB1,SACS,FAM107B,DLG2,DMD,DYNC1I1,DPYSL2,DTNA,DNM1L,ABCC9,E2F6,AASDH,EDNRA,KLHL5,OPTN,YAF2,FAM13A,PHF20L1,ABI2,GOLGA7,PLEKHA1,TMEM35A,EML1,EN2,DMTN,EPHA5,KCNMB2,RABEPK,SRRM1,EPS8,DENND4A,ETV1,RPS6KC1,TUBB3,CEP78,FGF12,FGFR1,MEX3B,SYNCRIP,SEMA4D,FOLH1,UFM1,TPK1,ATP6V1H,DACH2,ST6GALNAC3,STAU2,MSANTD4,MPP6,FYB1,PHYHIPL,STAG2,GAB1,HBS1L,GALC,ARPP21,ZNF234,ZNF274,ZNF559,DISC1,KIAA1841,MYOZ2,MSTN,ARFIP1,GDF9,PCDH17,MALT1,KIRREL3,RND1,COPS8,RAB30,GLS,ZNF638,LUZP2,FERMT2,ADGRA3,TDRKH,STON1,NUDT21,GRIA1,GRIA2,GRIA4,NR3C1,GRM1,BTN2A1,FAM19A2,RABL2A,PSIP1,MAP4K5,HAS2,HPS5,NXPH2,HMGB1,GABARAPL2,HNMT,ZNF491,HSP90AA1,MSL1,SOWAHA,NKD1,ZIC5,IL12A,RIPPLY2,INSM1,LRRTM3,ITPKB,KCNJ3,KCNMA1,KCNN2,STXBP5,TTYH2,LAMP2,HECTD2,NCOA7,SMAD1,MARK1,MAT2A,MATN3,SYT9,TM6SF1,LRP1B,SRSF12,SCAMP5,MKLN1,MN1,MSR1,CTNNA3,MYO9A,MYT1,NAP1L2,NCAM1,NDUFA5,NEUROD1,NF1,SLCO1C1,NFE2L2,NPY,NPTX2,SLC11A2,NTRK2,OCRL,OGDH,CLDN11,CNTN3,PCDH8,PCSK5,PCSK2,PDE3A,PDE3B,BEST3,CDK14,NALCN,CCSER2,PLCL1,RC3H2,SPATA6,EPB41L4B,POU3F2,PPM1B,PPP2R5C,PPP3CA,MAPK9,HYDIN,DIRAS2,PROX1,MASP1,SNRK,PIGG,CNTLN,PTCH1,MTMR10,OCIAD1,PTPRG,C1orf109,PTPRZ1,PTX3,PEX2,RAD17,ATG16L1,RAP1GDS1,ENOX1,DBX2,RBBP6,RDX,RFX3,TTLL7,RLBP1,SEC61A2,PBRM1,CCDC82,ZNF532,TMLHE,CARF,RORB,RPE65,TMEM100,MCMBP,SGSM1,LRRK2,KCNIP3,WLS,RMI1,MIR124-2HG,HOGA1,LRRTM4,TNFRSF19,ELMOD1,ZFP2,SUPT20H,HSPA4L,FERMT1,CPEB3,NTNG1,CHD9,SLITRK3,CCDC92,NLGN1,ANKRD6,ZNF365,PPP4R3A,RUFY2,LRRC55,ARHGEF40,SLC14A1,CPEB4,MBD5,CABCOCO1,ANKFN1,SNRPN,USP33,PDZD2,WDTC1,TRERF1,BDP1,SP4,NMNAT2,CLUAP1,UHRF1BP1L,KDM4C,SPART,C11orf87,TROVE2,SAMSN1,SSTR1,LARP4,TTBK2,SULF2,AJAP1,GSE1,FGD4,SYN2,SYPL1,SYT1,COBL,ANKRD12,CAMTA1,ADGRL3,FBXW11,TCF4,SATB2,TRIM2,RPGRIP1L,TCF12,PCDHGB7,WDR7,SYNE1,DOCK9,RALYL,GPRIN3,SLC35G2,FRYL,HIF3A,CCDC173,SIK3,FAM200B,DICER1,SIRT1,ITGB3BP,LEFTY2,HHIP,CDH22,SLC44A1,TIAM1,BHLHB9,ERCC6L2,TMOD1,BEX4,CSMD1,TNNT1,TPM1,NPL,RGMB,SYNPO2,PDSS1,STXBP4,TRPC1,ANKRD20A2,TTPA,TMEFF2,TUBB1,ZNF610,UBTF,PLEKHH2,USP1,BCL2L13,VAV2,VSNL1,GUSBP1,SLC47A2,PCDH20,ZFP37,ZNF17,MICU3,TRIM9,AGMO,FMN2,MKRN3,LYPD6,TCEAL7,REEP1,PLPPR5,SMARCAD1,MAP3K12,LRP8,CSDE1,ADAMTS9,PPP1R3F,FIP1L1,PDSS2,RTN4,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,TTC7A,KLHDC1,FRMD6,NETO1" MicroRNA hsa-miR-33b:mirSVR_lowEffct hsa-miR-33b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-191 1.10E-187 5.78E-189 5.32E-188 481 1989 "ABAT,SYN3,CLK4,SYS1,CSMD3,KLHL32,KLRC4,SLITRK1,GALNT13,ADD2,KIAA1211,PTCHD1,SLC24A4,GPR158,HECW2,KCTD16,TBC1D14,NME5,OSBPL6,C1QTNF3,SPARCL1,SMIM17,ALCAM,PCDH10,AMPD2,KIF6,ZFAT,OGT,LRCH2,ANK2,ANK3,CCDC146,LCORL,MAP4K3,PKP4,APBA2,APC,UPRT,GPAM,ALS2,CACHD1,AMER3,API5,LGR5,SFMBT2,PPP4R4,BRINP2,NUMB,EIF4G3,ATP6V0A1,LINC00847,MPDZ,SEC11C,BLM,KSR1,FUBP1,WASF1,CA8,CACNB2,CABP7,CAMK2G,ISPD,SEPT7,ZBED1,CDC42,LRRFIP1,LOC730101,TIGD7,CLGN,CBARP,CHM,CASC2,MS4A7,NDST3,PLAA,KIAA1549L,CLCN4,NRXN1,DNAJB5,AHCTF1,ACBD5,ZFP28,CREM,RBM39,GDA,TENM4,ARHGEF10,CSNK1G3,CST3,DZIP3,SDC3,APPL1,PLCXD3,CX3CR1,BOC,FGFR1OP2,TCAF1,RIPOR2,DCAF8,FRMPD4,TOX,ZNF337,MATR3,KCTD8,PABPC5,SPATA2,C8orf34,KIAA0319,FBXO25,DDX46,RHOBTB1,SPOCK3,NTM,DLG4,EXOG,HS3ST4,DNAH9,CPEB2,SLC25A18,ABI1,GNE,DTNA,DYRK1A,AASDH,EDN1,EDNRA,ATL1,CNNM1,FRY,YAF2,PHF20L1,SUGP2,MBNL2,KMT5B,GOLGA7,EIF4G2,PCOLCE2,STARD3NL,USPL1,LRRC17,EPHA5,KCNMB2,GPHN,ANKRD13B,IGSF6,ZNF549,MRPL37,CDKL3,SIRPB1,MRVI1,TMEM132C,ACSL4,SCML2,ATP8A1,CHST15,GORAB,SEC24B,SLC9B2,MED12L,GTF2IRD2,SCARA3,MEX3B,SYNCRIP,FLT1,ANKFY1,SGIP1,APOPT1,PDLIM5,NPTN,ZNF605,DACH2,STAU2,PNMA2,MSANTD4,FYN,MEGF10,GABRB1,CAB39,GAD2,AHCYL1,JPH4,RAPGEF6,MTHFD2,DISC1,ATP8A2,CYP46A1,ADAM28,GHR,PPARGC1A,COPS8,DBF4,SPIN1,GLI2,GLRB,GLS,TOX3,KDM2B,RAB40B,FERMT2,ADGRA3,GPM6A,LILRA2,GPR19,NUDT21,GPR37,PCLO,RAPGEF4,ATP2B1-AS1,GRIA1,GRIA2,GRIA4,GRM1,GRM2,TMEM25,ZBTB49,AP4S1,LINGO1,PSIP1,GUCY1B1,FRMD3,MIER3,SYNPO,SHISA6,CELF5,EID2B,C2orf72,SOWAHA,IGFBP1,IGSF1,SCIN,INPP5B,INSM1,SLC35G1,KCNK1,KCNK2,KCNMA1,KCNN2,CREG2,KLRC3,KPNA5,CYP27C1,KTN1,LAMP2,LIMS1,LMO2,NCOA7,MAP6,MBD1,MDM4,MEF2C,MID1,XRRA1,MMP16,WDR49,MOBP,ZNF680,MRPL42,SAMD5,ZNF92,TAGLN3,MYCN,MYO9A,P2RY13,NELL1,NELL2,NEUROD1,NF1,NFIA,NFIX,NOVA1,DNHD1,NTRK2,OGG1,OMG,OPA1,OPCML,OPHN1,OXTR,GPR137C,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDE4A,PDE4B,PDGFRA,SLC10A4,BEST3,CDK14,NLGN3,NALCN,SEMA5B,XRN1,GPSM2,FAM216A,HMGCLL1,ANKRD16,MAPKAP1,STRN3,LRP12,EPB41L4B,PACSIN1,SH3KBP1,PPP2R5E,KANSL1,PKIA,RAB39A,EPDR1,DIRAS2,SNRK,PTPRN2,PTPRO,ACSM5,QDPR,PID1,FAM66C,ZNF793,SH3TC2,FAM184A,RET,FIGN,ZDHHC4,SLC25A36,RPRD1A,ZFHX4,LGI2,ZNF532,RAVER2,ROBO1,ROBO2,CCDC25,ZC3H14,ZNF671,STK32B,MAP6D1,LGR4,ABCA11P,KCNIP3,RTN1,AP1AR,AMER2,CSRNP3,SCN2A,SCN2B,LRRTM4,TNFRSF19,PEAR1,CASC3,GALNT10,ITSN1,SH3GL3,KIF16B,FBXO11,ST6GAL1,NLGN1,ANKRD6,ABLIM3,PREX2,SLC2A5,BTBD3,DHX30,RAB3GAP1,SHANK2,SLC12A2,SLC15A2,SMARCD3,SMARCE1,RCOR3,ANKRD36,LIMCH1,RIMS1,MBD5,KIF13A,UNC80,PDZD2,MYT1L,SOX5,BDP1,HECW1,SPP1,NPAS3,NFASC,TAB2,SSTR2,SS18,ERBIN,STAU1,ZSCAN29,SEPT3,STXBP1,GSE1,NECAB1,FGD4,JMJD6,SYNE2,PLCB1,ANKRD28,SYT4,POPDC3,TAF9,DNMBP,CAMSAP2,ADGRL3,KIAA1107,WWC1,ANO4,TBX15,VWA3A,TCF4,ZFP90,RPGRIP1L,TCF12,AZIN2,SYNE1,PCDHB7,USP32P1,SLC35G2,FRYL,PMS2CL,SIRT1,LEFTY2,AP4E1,ZMAT3,AKTIP,ARL10,ACTR6,TLL2,RIMBP2,R3HDM1,KAT6B,TNS1,TPM1,C9orf85,ZNF384,SYNPO2,METTL3,TRPC3,TRPS1,TSC1,TMEFF2,TUBB1,RPRM,SLAIN1,PITPNB,FLRT2,VSNL1,WRN,GUSBP1,XPO1,SLC47A2,PCDH20,ZIC2,KCNT2,CFAP52,FMN2,GPR158-AS1,MKRN3,TCEAL7,ZBTB38,ANKS1B,ZFAND5,SMARCAD1,SYNC,PRTFDC1,RGMA,CSDE1,RNF103,TMEM178A,PCDH15,KCNAB1,WIPF2,MPPE1,RTN4,UBE3B,CASC15,ZNF248,TTC7A,SLC39A12,KLHDC1,FXR1,NETO1" MicroRNA hsa-miR-30b:mirSVR_highEffct hsa-miR-30b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.62E-191 3.16E-187 1.58E-188 1.45E-187 469 1895 "RALGAPA1,CLK4,ABHD6,ARID1A,CSMD3,GALNT16,GALNT13,RNF157,ADD1,BRAP,CDC7,SORCS1,ERMN,KIAA1211,LRFN2,ADRB2,AP2A1,AP2A2,AP1B1,ZNF608,INTS2,KCTD16,HACE1,TAOK1,C1QTNF3,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,ALS2,CACHD1,VAT1L,USP37,PPP4R4,TMEM263,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B1,ATP2B2,DPY19L3,ADGRB3,SEC11C,NRP2,BID,KSR1,DST,MTMR2,CACNB2,CALB2,CAMK2D,SLC25A14,CARS,CBS,LDB2,SLC5A11,USP2,SYNGR3,DGKI,SEPT7,ZBED1,LGI1,L3MBTL4,LARGE1,MAGI1,DLGAP1,TIGD7,CFL2,MS4A7,NDST3,KMT2C,NRXN3,FAM189A2,QKI,MAP4K4,NIPBL,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,ZFP28,SLC35F1,PNKD,CLOCK,SLC32A1,GDA,CRYM,SEC24C,OSBPL3,PDE4DIP,CTNND2,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TOX,TBC1D5,MATR3,KCTD8,MAML1,TOMM20,YTHDC1,JAKMIP2,C8orf34,MYEF2,CEP170,MAGI2,BLOC1S6,ALKBH8,PLPPR4,SACS,SPOCK3,RABGAP1L,WDR20,RAB39B,DMD,CPEB2,SLC12A6,PDCD6IP,MAMLD1,DYRK1A,DNM1L,ABCC9,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,MBNL2,EGR3,ASB3,TENM1,TMEM35A,EML1,DCTN4,EN2,EPB41,EPB41L2,LRRC17,KCNMB2,STX2,DENND4A,CDHR1,RCSD1,EXTL2,ABCA8,FABP7,SH3YL1,SCML2,ATP8A1,FCGR1A,AMOTL2,SCARA3,UBE2E3,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,SGIP1,SORBS1,UFM1,ATP6V1H,KHDRBS3,DACH2,NSG1,STAU2,MSANTD4,SARAF,NRG3,OGA,ZMAT1,STAG2,CHL1,GABRB1,TRAF3IP2,HBS1L,JPH4,GALR1,IP6K3,ERAP1,ATP8A2,KIAA1841,MYOZ2,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLRB,GLS,TNRC6A,GNAO1,GNAS,ADGRA3,PRUNE2,TDRKH,GPR19,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,GRM3,GRM5,CIT,FAM19A2,GUCY1B1,CELF3,RASSF8,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,ZDHHC15,NEGR1,SMAP1,RAB41,C2orf72,SOWAHA,ZIC5,DOCK7,ZNF678,DIPK1A,LRRTM3,LRRTM1,JAK1,JAK2,KCNC2,KCNJ3,STXBP5,KTN1,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAOB,MAP6,MARK1,LYPLAL1,MAT2A,SYT9,CHIC1,MEIS2,MID1,PPM1L,ERICH3,MRPL42,JAKMIP3,ADAM22,PABPC1L2A,NAP1L2,NAP1L3,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,OMG,PCDH9,PCSK1,PDE4D,PIRT,CDK14,PIK3CD,SNX10,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R5E,PRKACB,CEP41,EPDR1,SLC26A11,VPS13C,SLC22A23,LAMA1,ANKHD1,ELOVL2,PXK,TMEM260,PTPN13,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,ERI2,FIGN,RGS7,ARHGEF10L,TTLL7,SEC61A2,RNF220,RPRD1A,SETD5,EXD2,RAVER2,CARF,PCMTD2,LRRK2,CNTNAP3,ABCA11P,RTN1,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,LINC00461,SLC30A10,SUPT20H,ITSN1,FRMPD1,ARX,KIF16B,CPEB3,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,PAAF1,FAM81A,KANSL3,PKNOX2,SLC6A9,SPHKAP,TET1,ZFP1,SORCS3,SMARCE1,RCOR3,TTC17,LIMCH1,TMCC1,MYO16,SON,BDP1,DOK5,KDM3A,SP4,HECW1,BEX1,KIF1B,RBM26,NPAS3,SPART,CLASP2,SSTR2,NKAIN2,ERBIN,STAU1,ZSCAN29,ELOVL4,NEK4,RGL1,STXBP1,SYPL1,COBL,SYT4,DDHD2,CAMTA1,MCF2L,ADGRL3,ANO4,DMXL2,SATB2,USP22,CLASP1,WDR7,SYNE1,RALYL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,TMEM121,CRB1,SLC44A1,GZF1,TMEM9,TLL2,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,ZMYND8,DCBLD1,ANKRD20A2,SSBP2,RFTN2,TTC3,PITPNB,CCDC14,MICAL1,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,LYPD6,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,CA10,SLC30A4,MAP3K12,CSDE1,STOX2,RNF103,ADAMTS9,HPS4,NAV3,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,PAK5,HNRNPA3,PHTF2,CERS6,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-301a:mirSVR_lowEffct hsa-miR-301a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.58E-191 4.82E-187 2.29E-188 2.11E-187 460 1824 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,PWWP2A,PTCHD1,PCDH19,KCTD16,CC2D2A,AK2,LRRC7,BCAR3,PCDH10,PITPNM2,AMPD3,SEMA7A,CCDC146,MAP4K3,MYH7B,PPFIA2,PPFIA1,EPB41L5,TNRC6C,PPFIA3,SHTN1,IGDCC4,ASCL1,ATM,ATP1A2,MTMR9,B3GALT2,DOCK11,KSR1,BMPR1B,FUBP1,LINC00906,SGCE,NIPA1,LDLRAD4,CAMK2D,CAMK2G,CANX,VSTM2A,USP2,CDC42,DCLK1,LRRFIP1,MAGI1,NOG,SRSF11,MS4A7,EPS15L1,NRXN3,CLCN4,COG1,FBXO7,C4orf33,QKI,HECTD1,FHL5,CNN3,CNR1,IQCK,SLC25A27,SLC4A7,SLC4A8,TBPL1,BAG4,ZNF521,CREB5,HAPLN1,FEZ2,MICAL2,SUSD5,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,PHF19,ZNF337,RASSF2,LIN54,MAML1,DGKB,DGKG,TMEM170A,IP6K1,CTIF,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,KIAA0319,MAGI2,KLHL3,SNAP91,SV2B,AK5,G3BP2,FAM107B,KBTBD11,DLG2,GRIN3A,USP3,DNAH9,MED12,NR1D2,DNM2,CPEB2,SLC25A18,DRP2,DTNA,ECM2,DNM1L,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPB41,EPHA5,GPHN,CEP85L,EXTL2,KATNAL1,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FDFT1,FECH,OLFM1,TMEM164,PRKAG2,CAMSAP1,MEX3B,FOXG1,PCYOX1,RGPD5,FLT1,ANKFY1,STAU2,KBTBD12,DKK3,GAB1,GABBR1,GABRA3,ZNF44,CAB39,FAM120B,ZMYND11,GALC,JPH4,RAPGEF6,ZNF274,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,TOX3,CBX1,GPT2,ADGRA3,ATF7,DIPK1C,FUT10,MCHR1,GPER1,CECR2,PCLO,GRIA4,GRIK1,NR3C1,GRM2,LINC01089,KAT7,LINC01551,SOX21,ADAMTS6,GUCY1A1,MAP4K5,ATOH8,CELF3,RASSF8,HAS2,HPS5,FRMD3,MIER3,HLF,SCRG1,IGF1,NIM1K,IL11RA,LRRTM3,NME9,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNK1,KCNN2,KIF5C,KIT,IPO5,C2orf80,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,LRP1B,MEIS1,AFF1,AFDN,WDR49,MOBP,ZNF680,ADAM22,MYH6,MYO9A,NEXMIF,PABPC1L2A,NAP1L2,NCAM1,IDNK,NOS1,NOVA1,NPTX1,NPTX2,HCN1,NUMA1,TBC1D25,OGDH,OLR1,OPCML,ZDHHC22,KCNK10,GLIPR1L2,DPY19L2P2,PDE1A,PDE4B,PDE4D,GNG2,CYTL1,PFKFB3,NLGN3,PIK3C2A,PIK3R1,FAM216A,PLP1,PDZRN4,PMP2,STRN3,SCHIP1,ING3,FAT3,POU6F1,MED1,PPM1B,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,SNRK,MDGA2,ELOVL2,ZIK1,PTPRD,PTPRE,PPP2R3C,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,ARID4A,RBBP6,BSDC1,GTDC1,FIGN,RFX5,RIC8B,RNASEL,CCDC82,EXD2,ROBO1,RORB,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,PRR5L,LGR4,YJEFN3,RYR3,ZNF331,FAM192A,SATB1,ATXN1,SCN4B,SCN8A,LINC00461,SOX6,SELL,GALNT10,FOXRED1,SUPT20H,HSPA4L,PUF60,ITSN1,CPEB3,DOCK10,AMBRA1,FNDC3A,R3HDM2,SLITRK3,NUBPL,FAM81A,CDK5RAP3,SLC12A2,SLCO1A2,CPEB4,GKAP1,MAST1,SMARCD3,RCOR3,RIMS1,CABCOCO1,SNRPN,SON,KIF21B,FNBP1,KDM3A,EMC1,KDM4C,TSPYL2,RBM26,NPAS3,EPB41L3,LARP4,STAU1,SEPT8,DIP2A,ADHFE1,STXBP1,AJAP1,MLC1,VAMP1,SYT1,SLC37A2,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,PDLIM2,AGTPBP1,TBCEL,TMEM136,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,WDR7,AZIN2,SYNE1,TMEM151B,PCDHB7,USP32P1,FRYL,CRB1,GALNT17,ZFP91,HEY2,RIMBP2,PARD3,RBFOX2,NPL,DOK6,NR2C2,SMUG1,TRPS1,ANO5,HIRA,RPL7L1,EIF4ENIF1,UBE3A,LINC00689,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,CLDND1,GUSBP1,XRCC4,PCDH20,ZNF24,FMN2,SLC26A10,CELF4,SPIRE1,WNK1,EMSY,SLC38A1,CSDE1,EVI5,LINC02210,PRDM10,PCDH15,NAV3,SNX27,FIP1L1,FAM47E,SLC17A6,PDSS2,FAM13C,AMN1,DOCK8,RTN4,PHTF2,FBXO36,GJC2,CERS6,FAM219B,JMJD1C,ZNF248,RNF170,PIANP,NETO2,NETO1,SOCS4,SLC4A10,JPH3" MicroRNA hsa-miR-448:mirSVR_lowEffct hsa-miR-448:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-190 9.42E-187 4.28E-188 3.94E-187 464 1859 "VWA5B2,ABAT,KCNH8,ACADM,NCKAP5,TKTL1,KDM5D,ARID1A,CSMD3,NDRG2,GALNT13,AXIN2,UNC5A,KIAA1211,RNF150,ADRB2,SLC44A5,KLHL13,KCTD16,HACE1,OSBPL1A,OSBPL6,TAOK1,LRRC7,SMIM17,BCAR3,ARHGAP20,CARNS1,AMPH,ZFAT,ANK1,ANK2,LCORL,MAP4K3,ANXA7,APBB2,APC,AMER3,BCAS1,APP,SHTN1,SLC7A14,TMEFF1,SPTBN4,ARHGAP5,PCDHGB4,TMEM108,SLC4A4,ATP1B3,ATP2A2,ATP2B1,RNF182,N4BP2L1,NOL4,ATP6V1G2,DOCK11,ADAM23,BACH1,ADGRB3,ZNF599,BMPR1B,ARHGEF7,JAZF1,CACNA1I,CACNA1G,CACNA1D,CACNB4,CABP7,VSTM2A,ISPD,SPAG9,PRC1,LDB2,REPS2,CDC27,DCLK1,MAGI1,CIART,FOXN3,CHN2,CNOT8,KMT2C,CLCN3,CLCN4,CLTA,C4orf33,QKI,FHL5,CNN3,ARHGEF6,CNTN1,AKAP7,IQCK,AKAP6,SLC25A27,BTF3L4,AKAP5,RCHY1,TBPL1,AHCTF1,CLOCK,CREB5,HAPLN1,ANKRD44,RGS6,ARHGEF10,SIPA1L1,KIAA0040,PLCXD3,PNPLA8,GREB1,RIMS2,KIAA0408,FGFR1OP2,KIAA0586,KCTD8,TOMM20,PABPC5,ARMCX4,SPATA2,JAKMIP2,PLEKHM1,HP1BP3,CEP170,MAGI2,DDX46,RHOBTB1,PLPPR4,SACS,AK5,G3BP2,KBTBD11,DLG2,DLG3,DMD,USP3,DRD1,DNAJB6,AASDH,EDN1,FAM135B,EDNRA,EDNRB,ATL1,FEM1B,SEMA3D,FRY,PHF20L1,TENM1,C3orf18,EML1,EMX2,COQ7,IGSF6,RTN3,EXTL2,EFEMP1,DLC1,ZSCAN30,POLR1B,FGF12,SCARA3,IP6K2,SYNCRIP,FOXO3,ANKFY1,TACC2,NPTN,ATP2C1,ZNF605,KHDRBS3,CGREF1,STAU2,PNMA2,B3GAT1,FYN,MEGF11,DKK3,MEGF10,GABRA5,GABRB1,GABRG1,TRAF3IP2,FAM184B,GAD1,ERAP1,MTHFD2,KIAA1841,FAXC,GCK,ALDH1L1,NFU1,FREM1,PPARGC1A,GLDC,GLI2,GLS,ZNF638,GNG4,GPT2,ADGRA3,TDRKH,PRLHR,GPR22,NUDT21,EML4,CNTRL,ATP2B1-AS1,GRIA1,GRIA4,GRIK3,ADAMTS8,GRM1,GRM5,BTN2A1,BVES,PSIP1,HAS2,DDX19B,TNFAIP8L3,BACH2,GABARAPL2,IGFBPL1,HNRNPK,OPALIN,HTR2A,IRF8,LINC00667,C2orf72,C5orf24,NIM1K,NME9,ITGAV,SLC35G1,KCNA1,KCND3,KCNJ9,KCNJ16,KCNK2,KIF5C,IPO5,LAMP2,MAP2,MATN2,SYT9,ADAM11,MDM4,LRP1B,KCTD6,MIA2,KITLG,PPM1L,MMP16,MSR1,MT3,TAGLN3,CTNNA3,MTTP,MYCN,MYO5A,MYO9A,NEXMIF,PABPC1L2A,NEFM,NEUROD1,NF1,NFIA,NFE2L2,ALDH1L2,SLC11A2,HCN1,NTRK2,OGDH,OMG,CLDN11,OXTR,PCDHGC3,PCSK5,PDYN,TMOD2,PFKFB2,PFKFB3,PFKP,SERPINI1,PIK3R1,SNX10,KCTD15,PLCL1,PURG,PMP2,PMP22,CDIP1,RC3H2,LRP12,RETREG2,FAT3,PPM1B,CCDC144B,PPP3CB,PKIA,RAB39A,PRKCZ,EPDR1,GRAMD1C,HYDIN,BCAS3,VPS13C,MDGA2,PTCH1,ANKHD1,PLPPR1,UHRF1BP1,MTMR10,PTHLH,TMEM260,FAM66C,SH3TC2,SUSD4,ENOX1,ARID4A,RFX3,RFX5,RIT2,SLC25A36,RIC8B,LGI2,RERGL,SETD5,RAVER2,ROBO1,YY1AP1,ATP8B4,GLDN,ACER3,TCP11L1,LRRK2,CNTNAP3,RTKN,CLIP1,ZNF354C,RYR3,FAM182A,TMEM156,AP1AR,FAM19A1,ASIC4,IL17RB,SOX6,TRIM46,GALNT10,SFPQ,SUPT20H,KIF27,KIF21A,KIF16B,CPEB3,NTNG1,FBXO11,SLITRK3,BTBD3,SLC6A1,LRRC55,SLC8A3,ARHGEF40,NAPB,SLC15A2,GKAP1,LMBRD1,FAM126B,MYO16,KDM4B,USP33,SON,MYT1L,SOX2,SOX11,KDM3A,SP4,HECW1,MYCBP2,KDM4C,ZC3H13,KIF1B,SPART,TAB2,TROVE2,ITPRID2,SMOC1,NKAIN2,ERBIN,ZSCAN29,ADHFE1,KANK1,NECAB1,SYNE2,C12orf76,TACR1,ANKRD12,TAL1,CAMSAP2,ADGRL3,FBXW11,VWC2,TCF4,DMXL2,SATB2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SLC35G2,AP4E1,SLC44A1,FAM124A,RIMBP2,CSMD1,TPD52,TRIO,TRO,TRPS1,PPIL6,TTTY15,DNAJC12,CLIP2,SLC13A3,PCDH20,ZIC2,ZNF24,ZNF28,ELFN1,ZFP41,FMN2,MKRN3,LYPD6,SPHK2,REEP1,FSTL5,EML6,SMARCAD1,SYNC,EVI5,TMEM178A,NAV2,FIP1L1,PARP11,EPM2A,GOPC,RTN4,HNRNPA3,CERS6,ADAMTSL3,RNF170,NHSL1" MicroRNA hsa-miR-147:mirSVR_lowEffct hsa-miR-147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.56E-190 3.12E-186 1.36E-187 1.25E-186 448 1736 "SERPINA3,ABAT,ACHE,SYS1,TKTL1,ACTN1,FMNL2,GALNT16,GALNT13,UNC5A,PTCHD1,KIDINS220,NLGN4X,GPR158,KIAA1324,OSBPL6,AK2,TAOK1,C1QTNF1,SPOP,ALCAM,CARNS1,PCDH10,FAM135A,SYT13,AMPD3,LRFN1,LGR5,MIER1,PDXK,MADD,CADPS,MARCH3,DACT3,PCDHGB4,ASTN1,DYNLL1,ATP1A2,ATP2B2,ATP2B3,ZNF583,BCL2L2,BCS1L,CDK5R1,MMD2,CACNA1A,CACNA1B,CACNB2,CABP7,CALM1,PRC1,CBS,USP6,CD38,CDK11B,LGI1,L3MBTL4,MAGI1,CCPG1,CHGA,CHM,JAM2,LSMEM2,SLC22A6,RAB33A,NRXN3,TJP2,ABCG2,C4orf33,QKI,IGLON5,FHL5,CNN3,ARHGEF6,CNTN1,IQCK,PCYT1B,CABP1,SLC25A27,IFFO1,RTTN,ACBD5,TOGARAM2,ZFP28,CLOCK,RBM39,CREB5,SLC32A1,CLIP3,ABCG1,MICAL2,OSBPL3,CHD5,NCAN,FAM169A,UBXN2A,PLCXD3,CTNND2,DCAF4,RUBCN,USP6NL,FAM131B,CX3CR1,BOC,HDAC9,EARS2,DGKG,SCRN1,PABPC5,YTHDC1,DGCR5,RUSC2,TMEM130,SPOCK3,SRGAP3,NTM,DLG3,DLG4,DMD,HS3ST4,USP3,CD99L2,DNM2,CPEB2,CASP8AP2,DPP6,DRD1,DSCAM,GNE,DTNA,ECM2,TOM1,DUSP9,DNAJB6,FCF1,SYT15,CNNM1,YAF2,SUGP2,MBNL2,TNK2,ELN,EPB41,EPB41L2,DMTN,EPHA5,RTN3,TLR7,RRAGB,EYA1,ZNF461,CACNG2,ZIC4,TOMM40L,FER,FGF1,FGF11,FGF14,ACTL6B,HPCAL4,FOXG1,FOXF2,SYNCRIP,EVL,SEMA4D,FLNC,FLYWCH1,NELFCD,CAMKK2,TBR1,ARPP21,ZNF234,NEU3,ARFIP1,CYP46A1,ADAM28,MMADHC,PCDH17,MALT1,RUNDC3A,ZNF276,SPIN1,GLUL,PCDH11X,CBX1,KDM2B,GNAO1,ZNF782,GPD1,GPR17,STON1,DIDO1,GRID1,GRIK2,GRIK4,ADAMTS13,BTN2A1,LINC01551,GUCY1A2,RNFT2,ADAMTS6,IRAK3,UBE2QL1,HMGCL,HNMT,TLX1,CFAP126,OPALIN,CELF5,HTR5A,FAAP20,C2orf72,ZIC5,LIX1,BRINP3,INSM1,C2CD4C,SLC35G1,METTL21A,KCND2,KCNJ3,KCNMA1,KCNN2,KLRC2,IPO5,STXBP5,LAMP2,ARHGAP12,ZFYVE27,MAP2,MAP6,AQP11,MBNL1,CHIC1,LRP1B,MEIS1,MEIS2,XRRA1,MOBP,MOV10,DBNL,NRBP2,N6AMT1,CTNNA3,RSPO2,MYO7A,RTL5,FXYD6,P2RY13,NCAM1,NDUFA5,NELL1,NEUROD2,NFE2L2,ALDH1L2,DNHD1,NRCAM,HCN1,NTRK2,OGG1,PCDHGC3,PCDH9,PCSK2,CDK18,PDCD2,PDE4D,PDPK1,PFKFB4,FTO,PLP1,SLC25A23,HMGCLL1,MAPKAP1,RC3H2,TNPO2,NXPH1,POU6F1,MINDY2,PPP3CA,PRKAB2,RAB39A,PRKCG,PTHLH,TMEM260,PTPRO,NKAIN1,CCDC40,RASGRF1,FEZF2,KHDRBS2,RGS7,SEC61A2,CCDC82,SETD5,EXD2,CARF,GSTCD,KIRREL1,PCMTD2,SNX22,RPL15,UEVLD,SPIN3,KIAA0895L,GLDN,LRRK2,ABCA11P,WLS,ZNF331,DGLUCY,SEMA6D,SATB1,ATXN7,SCN2A,LRRTM4,ASIC4,MRAS,SGK1,MYO18A,NTNG1,SLITRK3,CCDC92,NUBPL,ZNF365,URGCP,DHX30,ARHGEF40,CCDC88A,SLC12A4,BTBD7,SLC20A2,SLCO1A2,NAXD,SMARCC2,RIMS1,SNAP25,MBD5,SNRPN,DOP1A,PDZD2,SOX10,ZSWIM8,CLUAP1,ENKUR,IQSEC2,CDK19,NFASC,ATP10B,PBLD,TROVE2,CLSTN2,ITPRID2,SSTR2,LARP4,SS18,SSPO,FCHO1,NCDN,ZSCAN29,SEPT8,DIP2A,ADHFE1,SEPT3,FGD4,ARHGEF9,SYP,SYPL1,ATP11A,MTCL1,TAF6,UNC5D,ALG1,SMG6,TCF4,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,TMEM151B,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,CRB1,ZNF34,THRA,TIAM1,TJP1,ERCC6L2,PRRT1,PIK3R5,TPD52L2,STXBP4,TRPC3,TRPS1,TMPRSS5,TSC1,CADM1,FLRT2,CCDC14,LMF1,VSNL1,NSD2,NPDC1,SLC13A3,XRCC4,LGI4,ZNF19,ZNF24,ELFN1,ZNF45,ATP6V0E2,ZNF70,MKRN3,ZNF154,ZNF213,SYNC,MFF,PRDM2,LRP8,XKR7,ADAMTS9,HPS4,VPS35L,SEMA3B,NAV3,RGS7BP,ADAMTSL3,TIGD6,SPATA13" MicroRNA hsa-miR-3175:mirSVR_lowEffct hsa-miR-3175:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.55E-190 4.24E-186 1.77E-187 1.63E-186 461 1841 "DPF1,ABAT,ABCF1,ASIC1,SYS1,FAM43B,GPRIN1,TMCC3,GALNT13,ADD1,BRAP,ERMN,GRAMD1B,KIAA1211,PTCHD1,SLC24A4,MTUS1,KIAA1324,WDR35,CC2D2A,LRRC7,CARNS1,PCDH10,DOC2A,PITPNM2,PHF12,CNIH2,CNTNAP1,ALS2,PHYHD1,VAT1L,BCAS1,SHTN1,MIER1,KIAA1614,PRX,SPTBN4,ZFYVE28,ARHGDIA,ARHGDIG,ARRB2,CDK13,MARK4,ASPH,ASTN1,TMEM108,ATP1A3,EIF4G3,ATP2B2,ATP6V0A1,ADGRB2,BCL7A,NRP2,CFLAR,BMPR1B,CDK5R1,BSN,MYRF,CDK5R2,BTRC,DDR1,CACNB4,LURAP1,CABP7,CAMK2A,CAMK2B,TRIM41,PRC1,CBFA2T2,LRBA,ARHGEF2,EVI5L,LOC730101,TIGD7,NUMBL,CHM,PLEKHB1,CASC2,NDST3,LHX2,NRXN3,COG1,STOML1,TMEM59L,FADS2,IQCK,AKAP6,BTF3L4,GAL3ST1,SMARCAL1,ZNF385A,SEC31B,CLOCK,C2CD2,CREM,RBM39,CRMP1,NCOR1,CLIP3,CS,CSF1,CSF1R,MICAL2,ATRNL1,RIMS4,PDE4DIP,SDC3,KIAA0040,CMTM5,CTNND2,USP6NL,CX3CR1,ECE2,ARHGAP32,DCAF8,TM9SF4,TBC1D5,MAML1,AIF1L,SIRPA,DNAL1,KIAA0753,SRGAP3,WDR20,SEC16A,DLG2,GRIN3A,HS3ST4,RPS6KL1,DNM2,SHANK1,DPP6,ACOT8,ABCC5,EDN3,EDNRB,SIDT2,CACNG7,OPTN,EFNA3,SH3GLB1,CELSR3,EGFR,MRO,EGR3,ING4,CERCAM,ELN,C3orf18,USPL1,EPB41L1,ANKRD13B,SPEG,CDHR1,ETV1,RTN3,RCSD1,MRVI1,FABP7,FCGRT,FKTN,STRADA,FGF11,TMEM164,UBE2E3,AGAP2,SEMA4D,ANKFY1,DCTN2,APOPT1,PDLIM5,CAMKK2,ATP2C1,DACH2,B3GAT1,BRSK1,GAB1,GABBR1,GAD1,JPH4,GHDC,SIGLEC8,INPP5K,STARD10,KIAA1841,ALDH1L1,GCNT2,GPR162,CYP46A1,GFAP,MMADHC,GGT7,C1QL1,KIRREL3,RUNDC3A,PCDH11X,INSM2,POLL,WDFY3-AS2,GOLGB1,PRRC2B,GPD2,PRUNE2,TDRKH,PCLO,RAPGEF4,RAPGEF1,DIDO1,C1QL4,GRIK1,ADAMTS13,NR3C1,ZNF496,CIT,FAM107A,FAM222A,MUM1,IGSF21,PADI2,C1orf94,SYNPO,AGBL5,CELF5,MSL1,C5orf24,KIAA1755,DISP2,IL6R,SCRT2,SLC6A17,METTL21A,KCNA6,KCNC1,KCND1,KCNN1,KHK,KLRC2,A1BG-AS1,VWA5A,NCOA7,LSS,ASPRV1,ZFYVE27,MAP4,SCAMP5,MSI1,MSR1,MSRA,PTOV1,TAGLN3,MTTP,C10orf105,MX1,MYH6,MYO7A,MYO9A,RTL5,ZNF862,PABPC1L2A,NBL1,CCDC13,NEUROD1,NEUROD2,NF1,NFIA,NFE2L2,ALDH1L2,NFYA,NHLH1,NOS1,CNOT4,SMIM11A,NUMA1,OPHN1,ZNF827,PBX1,PCSK2,PDE4A,HERC2P3,TMIE,CCSER2,FAM216A,PLIN1,HMGCLL1,MTRF1L,PLXNB3,ING3,SEPT4,EPB41L4B,PILRA,TNPO2,FA2H,FAT3,POLR2F,FSD1,PPARA,MED1,PPP2R5C,PPP5C,PRKCG,MAPK3,EPDR1,MAPK9,PRPSAP2,MASP1,CYBC1,SIDT1,CNTLN,PTAFR,PTPRE,PTPRO,PEX5,RAB5B,SLC25A48,FAM66C,RALGDS,IQSEC3,ARID4A,ZYG11B,PRIMA1,ARHGEF10L,RNF220,PBRM1,PNMA8A,KIRREL1,EPHA10,ZNF671,ATP8B4,GLDN,SGSM1,STK32B,ATAT1,KCNIP2,FAM192A,ATXN7,HOGA1,SCN3A,SCN4B,ELMOD1,SEC14L1,TRIM46,CASC3,FOXRED1,COPZ1,PUF60,SH3BGR,ITSN1,KIF16B,MYO18A,AMBRA1,FNDC3A,SLITRK3,CTXN2,PAAF1,ABLIM3,SLC1A7,RUFY2,SLC6A8,SLC8A2,RADIL,SLC8A3,CCDC88A,SLC9A5,TMEM132D,SPHKAP,SLIT1,SMARCC2,CDK5RAP2,RCOR3,INAVA,KDM4B,SCN3B,DOP1A,WDTC1,MYT1L,TRERF1,MYCBP2,ARHGAP26,KIF1B,IQSEC2,ZBTB43,NPAS3,DDN,ITPRID2,SMOC1,SSTR2,NKAIN2,STAC2,PHLDB1,SYT11,ARHGEF9,SYP,TACC1,SEMA4A,EXOC7,TAL1,WWC1,AGTPBP1,SMG6,KLHL4,MGRN1,TBX15,SIN3B,TCF7,TCF7L2,NAT16,TMEM151B,FAM189A1,NSD1,AKNA,TNS2,ARHGAP9,HIF3A,TF,KHDC1,C18orf54,ICAM5,TLR4,DAAM2,RIMBP2,TNFRSF1B,PIK3R5,SEZ6L,NPL,WBP2,ZNF346,PRMT8,SMUG1,STXBP4,TRPM2,KCNE5,TSC1,TTTY15,FAM155A,GORASP1,FLRT2,FLRT1,PLEKHH2,BCL2L13,MTCH1,PLPPR2,TOM1L2,ZNF19,CELF4,REEP1,TMEM198,PLPPR5,MEIS3,PMEPA1,EMSY,PRDM2,LRP8,CSDE1,GDPD5,PRDM10,NAV2,SNX27,LINC00632,PDSS2,HNRNPA3,TMEM63C" MicroRNA hsa-miR-200b:mirSVR_highEffct hsa-miR-200b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.20E-189 5.17E-185 2.07E-186 1.90E-185 454 1795 "SDE2,ABAT,KCNH8,ACHE,CLK4,SYS1,ARID1A,XKR4,CSMD3,SLITRK1,ADD3,ERMN,PWWP2A,PTCHD1,NLGN4X,SLC24A4,INTS2,MTUS1,GPR158,HFM1,ABCD2,ARHGAP20,PCDH10,FAM135A,GPRASP2,ANK2,LCORL,MAP4K3,PPFIA1,PKP4,PARG,ALS2,VAT1L,SHROOM2,CDC14B,IGDCC4,CAPRIN2,ASPH,NUMB,STX16,ATP2A2,ATP2B1,DPY19L3,ADGRB3,MPDZ,PROM1,CDK5R1,SYNJ1,ST3GAL5,FUBP1,JAZF1,SGCE,OSGIN2,IL33,MMD2,CA8,CACNB2,THSD7A,PTBP2,CAST,SPAG9,CDC27,ZMYM4,NOG,CFL2,CHM,CHN2,NRXN1,TJP2,FAM19A5,DNAJB5,QKI,CNN3,CNTFR,AKAP7,SLC25A27,BTF3L4,COL9A2,SLC4A7,SLC4A8,GAL3ST1,BAG4,GDA,CS,CSF1,SEC24C,CSF3R,FEZ2,ARHGEF10,CSNK1G3,SUSD5,PHACTR3,FAM169A,PITPNM3,CTNND2,USP6NL,CCDC144A,DOCK4,GPRASP1,ARHGAP24,DCAF8,ZFYVE16,LIN54,MATR3,KCTD8,TMEM170A,GIT2,SIRPA,ELMSAN1,ZEB2,ZBTB24,MYEF2,RUSC2,BLOC1S6,PLPPR4,WDR20,CHRDL1,EXOG,RAB39B,DMD,NYAP1,DNAH9,DYNC1I1,CPEB2,DTNA,MAMLD1,DNAJB6,ABCC9,CNNM1,TMTC1,FSD1L,YAF2,EGR3,GOLGA7,EIF4G2,ELAVL2,PAN3,TUBD1,MTSS1L,EPS8,TAOK3,DLC1,TESK2,FER,POLR1B,FGFR1,AMOTL2,PRKAG2,FHL1,POLK,MEX3B,FOXG1,FOXF2,ATP13A4,ANKFY1,SGIP1,NOP56,JKAMP,UFM1,PDLIM5,FAM49B,CELF1,ST6GALNAC3,STAU2,OGA,FYN,CAB39,ARPP21,ZNF274,GART,KIAA1841,GATM,MSTN,SESN1,FREM1,MALT1,COPS8,GLS,TNRC6A,INSM2,FERMT2,GPM6A,EML4,CECR2,GRIA2,GRIA4,NR3C1,FAM19A2,PSIP1,MAP4K5,WIF1,RASSF8,HPS5,ARHGAP19,MIER3,HLF,HMGB1,HNRNPK,NEGR1,AGFG1,ZNF181,TJAP1,IGSF1,IL12A,LRRTM3,SLC35G1,KCND2,KCNJ3,KCNJ16,KIF5A,STXBP5,LIMS1,HECTD2,NCOA7,SMAD9,MAP2,LDLRAD3,LRP1B,MEST,POC1B,ERICH3,MRPL42,MYCN,NAP1L2,OTOGL,CNOT4,NOVA1,NPTX1,SMIM11A,HCN1,NTRK2,NUCB2,IGSF11,P2RY1,CNTN3,PCDH8,PCSK2,PRTG,GPR85,GNG2,PENK,PFKP,CDK14,SERPINE2,SERPINI1,NALCN,ANLN,FAM218A,A2ML1,SNX10,XRN1,KCTD15,PLCL1,HMGCLL1,PMP22,TRHDE,PSAT1,SCHIP1,SDK2,NXPH1,POU6F1,PPARA,PPM1B,PPP2R2C,PPP2R5E,RASGEF1B,PRKACB,CEP41,PKIA,PRKCB,MAPK7,MAPK9,DIRAS2,RELN,SAMD9,WBP1L,SIDT1,SNRK,CNTLN,PTCH1,PLPPR1,BDNF-AS,MTMR10,PTHLH,TMEM260,PTPN13,OCIAD1,PTPRD,EML5,PTPRZ1,ZSCAN2,FAT4,OXR1,ARID4A,RADX,MSANTD2,RDX,RET,REV3L,ERI2,FIGN,SEC61A2,SLC25A36,NUDT11,RNASEL,RPRD1A,CCDC82,ZNF532,RAVER2,CARF,ROBO1,RORB,CCDC102B,RPE,ARMH4,FBXW7,KIAA0895L,ACER3,TCP11L1,CLIP1,ZNF568,TRAPPC13,AP1AR,AMER2,SEMA6D,SCN8A,SCP2,ELMOD1,SUPT20H,KIF21A,ITSN1,SHC4,AMBRA1,FNDC3A,R3HDM2,SEC31A,ANKRD6,ZNF365,FAM81A,SLC6A1,KDM4D,SLC8A3,SLC12A2,SLC14A1,SLC15A2,SLIT1,ZFP1,ZNF667,SORCS3,MYH15,SMARCE1,SNAP25,MBD5,KIF13A,SNRPN,UNC80,FAM219A,PDZD2,SOX1,SOX2,ZCCHC24,KIF21B,BDP1,DOK5,KDM3A,ENKUR,CAND2,KDM4C,ZNF423,KIF1B,SPART,C11orf87,CLASP2,TROVE2,POGZ,ITPRID2,ZNF302,MPRIP,SEPT8,RGL1,DIP2A,PHLDB1,KANK1,ZC3H4,SYNE2,VAMP1,VPS13A,SYT1,ANKRD28,CAMSAP2,ADGRL3,TBCEL,TMEM136,SATB2,ZEB1,WASHC4,CLASP1,RALYL,AKNA,ARHGEF12,PUM2,SLC35G2,CCDC173,TEX15,RNF216P1,ZFPM2,TGFBR3,ASXL3,TLL2,ERCC6L2,CSMD1,TRIO,RUNDC3B,AMACR,RFTN2,TUBB2A,TMEFF2,FAM155A,UGT8,SLAIN1,VLDLR,TBC1D15,RBFOX3,WIPF1,CLIP2,CLDND1,GUSBP1,XRCC4,ZIC3,ZNF23,TRIM9,MKRN3,LYPD6,ZBTB38,REEP1,TFIP11,SMARCAD1,SYNC,EMSY,EVI5,TMEM178A,NAV3,FAM13C,PAK5,KAT6A,PHTF2,NLRP3,ZNF248,RNF170,KLHDC1,FXR1,IFT88,SLC4A10,GAN" MicroRNA hsa-miR-383:mirSVR_lowEffct hsa-miR-383:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.36E-187 7.66E-184 2.94E-185 2.71E-184 449 1766 "RALGAPA1,ACADM,ACLY,FAM43B,ARID1A,GPRIN1,CSMD3,NDRG3,ADAR,ADD1,SORCS1,USP31,ADORA2A,RNF150,BEND6,MTA3,AP2A2,OSBPL1A,OSBPL6,PLA2G6,SPOP,ALCAM,ARHGAP20,PCDH10,UNC79,DPP10,LRCH2,MYH7B,PKP4,BCAS1,TNRC6C,APP,SHTN1,CDC14B,CDK13,NCOA1,TMEM108,ATM,SLC4A4,ATP1B3,MTMR9,ATP6V1G2,LINC00847,BBS2,ZNF599,BMP7,ARHGEF7,C5,RAB29,WASF1,IL33,CFAP410,CALB1,CAPN3,CH25H,HIP1R,MAP7,AIFM1,C1orf52,CDC42,DCLK1,LRRFIP1,MAGI1,CRLF1,NUMBL,CIART,CFL2,FOXN3,CHRNA4,DLGAP3,RAB28,NRXN3,DGCR9,SRP14-AS1,FHL5,ARMC8,COL11A2,ZFP28,CNRIP1,MFSD4A,CHD1L,SLC32A1,GDA,ABCG1,LRRC3B,OSBPL3,CST3,CTH,PUM1,ZSCAN23,CCDC144A,NOS1AP,KIAA0408,ARHGAP24,KCTD8,IP6K1,DNAL1,ARMCX4,DCC,YTHDC1,ZNF804A,ZEB2,ELMO1,MFAP3L,BLOC1S6,RHOBTB1,PLPPR4,SACS,SV2A,NTM,WDR20,CCDC3,DLG2,DLG4,EXOG,GRIN3A,ACOT8,PDCD6IP,DYRK1A,ABCC5,E2F5,EDIL3,SNX29,CNNM1,RASGRP1,OPTN,EIF4G2,ELAVL2,PLEKHA1,C8orf37,DCTN4,EPB41,EPB41L1,RCAN2,LRRC17,KCNMB2,RABEPK,SRRM1,NCALD,RTN3,RCSD1,RRAGB,FAM198B,WAC,FABP7,TMEM132C,ZIC4,ATP8A1,TESK2,SUCO,FOXO3,ANKFY1,SLC37A3,DCTN2,COQ5,EFCAB2,NBEA,SORBS1,SMC2,PDLIM5,CAMKK2,ZNF605,KHDRBS3,NSG2,ST6GALNAC3,PNMA2,KBTBD12,PHYHIPL,STAG2,MEGF10,GAB1,GABRB3,HBS1L,B4GALNT1,ARPP21,ZNF274,IQGAP2,MTHFD2,DNER,GATM,TUBGCP4,GPR162,GGT5,KIRREL3,HPGDS,GLRB,PCDH11X,ZNF638,LUZP2,DCLK2,GP1BB,GPM6B,GPR17,PCLO,STMN2,DIDO1,RFFL,GRIK1,SPACA9,NR3C1,PRDM5,GRM8,CIT,ADAMTS6,GUCY1B1,MAP4K5,CELF3,ZHX1,NEGR1,HSD17B1,FAM95B1,C2orf72,RBPJ,USP54,IL6ST,LRRTM3,KCNA2,KCND1,KCNF1,KLRC2,LAMP2,STMN1,LIFR,LIG4,PAXBP1,FGFBP3,PIK3AP1,GPR155,MAPT,MBD1,MBNL1,MBP,SYT9,CHIC1,MEF2C,KCTD6,MID1,AFF1,MOBP,CPNE9,SESN3,MSR1,MTTP,C10orf105,HS6ST3,LYRM9,MYO6,ZNF862,BEX5,NCAM1,ZC3H12B,NDUFA5,NELL1,NF1,NFIA,NFE2L2,VWA2,NPR2,SLC11A2,NRCAM,NRGN,HCN1,TBC1D25,CHAMP1,OMG,OPCML,OPHN1,PAX6,DPY19L2P2,PCMT1,PCSK2,PDE3B,PDE4B,PDE4D,ENPP2,PIK3R1,CCSER2,SLC25A23,PURG,PMP22,LRP12,EXOSC10,PRRX1,PPP2R2B,CRLS1,PPP2R5E,PPP3CB,PPP3CC,KANSL1,PRKACB,PKIA,PRKCG,RELN,VPS13C,CNTLN,ZSCAN32,PTPRB,OCIAD1,PTPRE,PEX2,TTC13,RAB5B,CEP97,SLC25A48,PLEKHB2,ZNF793,NWD1,ROGDI,OXR1,RBBP6,ZMAT4,TRIM68,GTDC1,RGR,RGS12,PRIMA1,SEC61A2,RIC8B,LGI2,CCDC82,ALG9,GSTCD,CYB561D1,KIRREL1,CCDC25,RPE65,FBXW7,GLDN,ACER3,SOX8,ATAT1,KCNIP3,SEMA6D,LRRTM4,SLC30A10,SEC14L1,CASC3,SCAF8,PPP1R9A,PPM1E,FERMT1,ST6GAL1,CCDC92,CTXN2,SEC31A,SLC2A5,PPP4R3A,SMTN,KANSL3,LRRC55,SEPHS1,RAB3GAP1,CCDC88A,KBTBD4,SLC12A2,SLC15A2,TMEM132D,ELMO2,SLCO1A2,GKAP1,MYH15,SMARCE1,ANKRD36,SNRPN,SCN3B,MYT1L,FNBP1,ZSWIM8,ZC3H13,KIF1B,CDK19,TSPYL2,TAB2,ATP10B,SST,SSTR1,NCDN,ZSCAN29,DIP2A,ADHFE1,KANK1,AJAP1,MLC1,SLC37A2,PJA1,TBCEL,MGRN1,ACSL6,TCF4,SATB2,TCF12,RALYL,PCDHB7,ARHGEF12,USP32P1,ARHGAP9,HIF3A,DICER1,ZFPM2,AP4E1,SLC44A1,TMEM9,ACTR6,FAM124A,CSMD1,PIK3R5,RBFOX2,SYNPO2,ELP5,TRIO,FNDC5,TTPA,TUBB1,AMOT,VLDLR,WIPF1,GUSBP1,ZIC3,MICU3,ZNF28,ZNF45,ZBTB16,POLR3H,PLPPR5,SMARCAD1,DHX33,EVI5,GDPD5,LINC02210,STOX2,PCDH15,NAV3,FIP1L1,ITM2C,PLSCR4,FAM13C,AMN1,DOCK8,CASC15,NUP214,CERS6,FAM219B,TRAM2-AS1,ZNF248,VANGL2,TTC7A,IFT88,NETO1,LAS1L" MicroRNA hsa-miR-1283:mirSVR_highEffct hsa-miR-1283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.95E-187 1.66E-183 6.14E-185 5.65E-184 467 1915 "RALGAPA1,SDE2,ACADM,CLK4,NCKAP5,SYS1,ADAR,KLRC4,ADD1,CDC7,SORCS1,PWWP2A,ADORA3,RNF150,ZNF608,INTS2,HECW2,HACE1,NME5,WDR35,OSBPL8,TAOK1,LRRC7,ALAD,SRPX,BBOX1,UNC79,CDC42BPA,LRCH2,FGD2,CCDC146,PARG,SHTN1,SEMA4G,ARNTL,ASPH,DDX3Y,ATM,ATP2A2,ATP2B1,ALDH7A1,DPY19L3,ATP6V1G2,TTLL9,MPDZ,SEC11C,MIR9-3HG,DST,SYNJ1,SCAPER,JAZF1,OSGIN2,IL33,MMD2,LURAP1,CALB1,CANX,CAST,CH25H,MAP7,LRBA,CDC27,CDH2,CDH10,ZMYM4,L3MBTL4,NOG,CFL2,GPR37L1,CHN1,SYNPR,CNOT8,IGFBP7-AS1,NRXN1,TPP1,FAM19A5,C4orf33,QKI,SULT4A1,HECTD1,NIPBL,HOMER3,TMEM155,CNTN1,AKAP6,SUMF2,BTF3L4,SLC4A7,RCHY1,ZFP28,SLC35F1,CDC42BPB,PREPL,CREM,CRHBP,HINFP,CRYM,SNCAIP,SEC24C,FEZ2,SUSD5,SIPA1L1,SOCS5,CNTNAP2,UBXN2A,PUM1,ST18,CCDC144A,HDAC9,TOX,ZFYVE16,MATR3,MAML1,TMEM170A,DAPK1,TOMM20,DNAJC6,C8orf34,MYEF2,HP1BP3,MAGI2,DDX46,ALKBH8,RHOBTB1,PLPPR4,SNAP91,SACS,NTM,RABGAP1L,DYNC1I1,CDON,CPEB2,CASP8AP2,ABI1,GNE,ECM2,GOLT1B,EBF1,EDNRA,PHC2,HIPK3,FRY,YAF2,PHF20L1,APH1A,MBNL2,EGR3,EIF4G2,COPS4,PLEKHA1,RGS17,GPHN,CEP85L,CDKL3,VPS26C,DUSP27,WAC,FABP7,TMEM132C,TAOK3,SCML2,CEP78,GTF2IRD2,KIAA1109,FGF12,FGF14,TMEM164,UBE2E3,MEX3B,CAP2,PCYOX1,SYNCRIP,C2orf88,TMEM107,STAMBP,NSG2,ST6GALNAC3,SARAF,MEGF10,GABRA1,GABRB1,GABRG2,TRAF3IP2,GAD1,GAD2,ZMYND11,RAPGEF6,SALL3,DISC1,KIAA1841,NEU3,MSTN,PPARGC1A,MALT1,GK,COPS8,RNPS1,SPIN1,RAB30,GPR75,TNRC6A,GLUL,ZNF638,KDM2B,HTATSF1,GNAO1,GPM6B,FUT10,STON1,GPR37,GRIK2,NR3C1,GRM3,KIF3A,FAM19A2,ZBTB49,PSIP1,HPS5,HMGCR,HNF4G,SHISA6,SOWAHA,RBPJ,KIAA1755,USP54,BRINP3,DIPK1A,RIPPLY2,ZNF385B,LRRTM1,NME9,ITPKB,KCNK1,KIF2A,STXBP5,KTN1,LAMP2,HECTD2,NCOA7,NAT8L,MAN2A2,MAP4,MATN3,LRP1B,MEF2C,SRSF12,MIA2,AFDN,CD200,COMMD5,SESN3,ADAM22,PABPC1L2A,TCEAL5,HNRNPM,NEK1,NOVA1,NPTX1,NPTX2,SLC11A2,SMIM11A,HCN1,TBC1D25,OLR1,OPHN1,CLDN11,DPY19L2P2,PCDH8,PDE4D,ENPP2,GPR85,PFKFB2,CAMKV,TMEM38A,HMGCLL1,PRIMPOL,MAPKAP1,CDIP1,FAT3,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PKN2,MAPK9,HYDIN,DIRAS2,PRPSAP2,SIDT1,GON4L,GDPD2,CNTLN,PTCH1,PTHLH,PTK2,PTN,TMEM260,PTPRB,OCIAD1,CASTOR1,PTPRZ1,PEX2,USP47,FAT4,NWD1,RAP1GDS1,ZNF493,OXR1,ARID4A,RBBP6,RBBP8,VEPH1,KHDRBS2,ZDHHC14,BSDC1,RDX,SLC6A15,ZYG11B,RFX3,RFX4,UBR7,RGS10,NUDT11,PBRM1,ZFHX4,SETD5,CARF,RORB,YY1AP1,MRAP2,RPL15,ARMH4,FBXW7,LRRK2,ABCA11P,SOX8,NCBP3,ZNF331,MIR124-2HG,SATB1,ATXN2,ATXN7,SCN3A,FAM19A1,FNIP1,HES6,TRA2B,SH3GL3,FERMT1,SHC4,CHD9,FBXO11,FHOD3,SLITRK3,ABLIM3,SLC1A3,FAM81A,BTBD3,WDR47,SEPHS1,ARHGEF40,SLC11A1,SLC12A2,MTERF2,ATF7IP,CPEB4,RCOR3,SNAP25,MBD5,KIF13A,SNRPN,FAM126B,PDZRN3,MYO16,USP33,SON,SOX1,TNIK,BDP1,SP4,MCF2L2,RBM26,NPAS3,TROVE2,THSD1,SMOC1,EPB41L3,LARP4,NKAIN2,SULF2,VAMP1,VPS13A,SYT1,COBL,MTCL1,TAL1,UNC5D,ALG1,ADGRL3,KLHL4,EHBP1,TCF4,DMXL2,TCF7L2,TRIM2,PCDHGA11,RALYL,HIF3A,FAM200B,SIRT1,ITGB3BP,SLC44A1,ERCC6L2,TMPO,KAT6B,TP53BP2,TPD52L2,TPM1,TPM3,RGMB,METTL3,STXBP4,DCBLD1,ZKSCAN5,TMEFF2,CADM1,RPL7L1,UBE3A,UBTF,SLAIN1,FLRT1,PLEKHH2,TBC1D15,NSD2,CLDND1,ZIC3,ZNF24,ZNF28,KCNT2,AGMO,FMN2,LYPD6,CELF4,FSTL5,ZNF189,ZNF195,WNK1,EMSY,MFF,PRDM2,NAV3,FIP1L1,MPPE1,PLSCR4,FZD3,UBE3B,SMIM8,HNRNPA3,JMJD1C,NLRP3,ZNF248,TIGD6,SNX14,SLC39A12,KLHDC1,SLC4A10,SENP7" MicroRNA hsa-miR-107:mirSVR_lowEffct hsa-miR-107:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.48E-186 8.31E-183 2.87E-184 2.64E-183 471 1955 "ABR,SYN3,NDRG3,ADAR,SLITRK1,ADCY6,CCDC85A,ADD1,PLEKHH1,UNC5A,ADRB2,KIDINS220,AP2A1,ZNF608,MTUS1,GPR158,KLHL13,OSBPL1A,OSBPL6,LRRC7,SEMA6A,ALCAM,ARHGAP20,GPRASP2,AMPH,AMT,LCORL,APC,USP37,SHTN1,MADD,IGDCC4,ZFYVE28,ARHGAP5,CDK13,STK33,PCDHGB4,BRINP2,NUMB,TMEM108,ATP2B2,MTMR9,CADM3,DOCK11,ADAM15,BACH1,ADGRB3,SEC11C,DCAF5,CDK5R1,SYNJ2,FUBP1,SCAPER,MTMR3,C5,MYRF,BTRC,CACNA1B,CACNB4,CANX,SYT6,SPAG9,KRIT1,USP2,NEURL1,CDC27,CDC42,SRSF11,ASIC3,MS4A7,ARHGAP22,RAB33A,CLU,DGCR9,FBXO7,NIPBL,CNN3,AKAP6,COL9A1,IFFO1,TBPL1,AKAP12,ANKRD44,CRYM,CSF1,CSNK1G3,IPCEF1,SOCS5,CST3,DZIP3,ERC2,USP6NL,NOS1AP,ARHGAP32,KATNAL2,HDAC4,RIMS3,TMEM170A,ARMCX2,PLEKHM1,ELMO1,TIAM2,COPS7A,SACS,SV2A,G3BP2,WDR20,DLG4,DMD,DMPK,USP3,SLC29A4,TRAPPC9,DYNC1I1,NR1D2,CPEB2,SLC12A6,FAM57B,ATN1,MAMLD1,DNAJB6,ABCC5,DNM1L,GOLT1B,EDIL3,ATL1,SEMA3D,EGFR,ABI2,EIF4G2,COPS4,PAN3,DCTN4,USPL1,EN2,RCAN2,LRRC17,GPHN,ERBB4,SPEG,CDHR1,VPS26C,RTN3,SIRPB1,EZH1,NRN1,ZIC4,TAOK3,ATP8A1,STRADA,GORAB,SEC24B,PRKAG2,SCARA3,UBE2E3,HPCAL4,SYNCRIP,FOXO3,SEMA4D,FLT1,PSD2,SMC2,ZNF605,PRELID3A,CELF1,ST6GALNAC3,PNMA2,MEGF11,GAD1,FAM120B,GALC,IP6K3,C15orf41,ATP8A2,IGSF5,ALDH1L1,TUBA8,CYP46A1,NFU1,USP19,COPS8,SPIN1,GLS,ZNF638,GNG4,ATF7,GPER1,EML4,TMEM121B,STMN2,GRIA4,GRM1,GRM8,CLASRP,RNF165,COQ10A,MFSD2A,FAM107A,ADAMTS6,RASSF8,FRMD3,ARHGAP19,ZNF491,HNRNPK,AGFG1,LRRC75A,SHISA6,ICA1,IRF8,C5orf24,SCIN,ZNF678,KCND2,KCNH2,KCNMA1,KCNQ3,IPO5,LMO2,VWA5A,ASPRV1,MAP6,MAT2A,SYT9,CHIC1,TM6SF1,MEF2C,MEIS2,MITF,MMP16,MN1,JAKMIP3,MSR1,MT1M,CTNNA3,NBL1,NDP,NDUFA5,NEUROD1,NFIA,NHLH1,NINJ2,NME4,VWA2,OMG,OPA1,ZNF827,PAH,PAK3,PAX6,PCDHGC3,PCDH9,PCMT1,PCSK5,PDE4B,PIRT,ENPP2,PDYN,SLC10A4,BEST3,SEMA5B,CAMKV,PIK3R1,PKD1,PURG,PRIMPOL,MAPKAP1,EXOSC10,ING3,RETREG2,EPB41L4B,FAT3,POU3F2,MINDY2,PPM1B,PPP2R2B,CRLS1,PPP2R5C,PPP3CB,PRKAB2,PKIA,RAB39A,EPDR1,GRAMD1C,PRPH,MASP1,RELN,CNNM2,SAMD9,WBP1L,DEF8,PIGG,PTHLH,SPDL1,PTN,PTPN13,PTPRB,PTPRE,FAM120C,ACSM5,TTC13,TMEM255A,RAD51D,SH3TC2,NWD1,RASGRF1,ARID4A,RBBP6,KHDRBS2,BSDC1,ZYG11B,REV3L,PRRT2,GTDC1,RGS4,ARHGEF10L,RIT2,ALG9,PNMA8A,ELP2,CCDC102B,TMEM100,UEVLD,PRR5L,ACER3,ABCA11P,KCNIP3,ZNF568,TMEM156,DGLUCY,SAFB,ATXN1,ATXN2,ATXN7,LRRTM4,SCN7A,PRCD,SLC30A10,ZFP2,SEC14L1,SOX6,FOXRED1,TRA2B,SCAF8,SGK1,FRMPD1,ST6GAL1,URGCP,PREX2,DHX30,LRRC55,KDM4D,SLC8A2,CCDC88A,ATF7IP,SLN,GKAP1,SMARCC2,RIMS1,MBD5,KIF13A,SNRPN,SON,WDTC1,MYT1L,TNIK,IZUMO4,PEG10,DBNDD2,KIF1B,NFASC,TAB2,ATP10B,TROVE2,SMOC1,SSTR1,LRRC4,FCHO1,NEK4,SEPT8,CEP68,PHLDB1,VAMP1,FNDC9,DNAJC9,SYN1,SYN2,SYP,SYPL1,SYT4,MMS19,KAZN,MTCL1,CAMTA1,TAF9,TAL1,CAMSAP2,AGTPBP1,TBX15,VWC2,TCF4,TCF7,TCF7L2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,AHCYL2,PMS2CL,TMEM9,TLR4,ZFP91,ERCC6L2,HEY2,KCTD2,PIK3R5,TPD52,TPM1,SYNPO2,TRPC1,PPIL6,HIRA,UGT8,DNAJC12,MEAF6,BEST1,NSD2,WNT7A,XPO1,SF1,ZIC1,KCNT2,TRIM9,NDRG4,ZBTB38,REEP1,TMEM237,DPYSL5,EMSY,CADM2,PRDM2,PRDM10,LMAN2L,RNF103,CIAPIN1,NAV2,ITM2C,TRIM16L,C12orf4,RGS7BP,FZD3,DOCK8,VANGL2,NHSL1,FXR1,AP3B2,SOCS4,SLC4A10,SPATA13" MicroRNA hsa-miR-103:mirSVR_lowEffct hsa-miR-103:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.48E-186 8.31E-183 2.87E-184 2.64E-183 471 1955 "ABR,SYN3,NDRG3,ADAR,SLITRK1,ADCY6,CCDC85A,ADD1,PLEKHH1,UNC5A,ADRB2,KIDINS220,AP2A1,ZNF608,MTUS1,GPR158,KLHL13,OSBPL1A,OSBPL6,LRRC7,SEMA6A,ALCAM,ARHGAP20,GPRASP2,AMPH,AMT,LCORL,APC,USP37,SHTN1,MADD,IGDCC4,ZFYVE28,ARHGAP5,CDK13,STK33,PCDHGB4,BRINP2,NUMB,TMEM108,ATP2B2,MTMR9,CADM3,DOCK11,ADAM15,BACH1,ADGRB3,SEC11C,DCAF5,CDK5R1,SYNJ2,FUBP1,SCAPER,MTMR3,C5,MYRF,BTRC,CACNA1B,CACNB4,CANX,SYT6,SPAG9,KRIT1,USP2,NEURL1,CDC27,CDC42,SRSF11,ASIC3,MS4A7,ARHGAP22,RAB33A,CLU,DGCR9,FBXO7,NIPBL,CNN3,AKAP6,COL9A1,IFFO1,TBPL1,AKAP12,ANKRD44,CRYM,CSF1,CSNK1G3,IPCEF1,SOCS5,CST3,DZIP3,ERC2,USP6NL,NOS1AP,ARHGAP32,KATNAL2,HDAC4,RIMS3,TMEM170A,ARMCX2,PLEKHM1,ELMO1,TIAM2,COPS7A,SACS,SV2A,G3BP2,WDR20,DLG4,DMD,DMPK,USP3,SLC29A4,TRAPPC9,DYNC1I1,NR1D2,CPEB2,SLC12A6,FAM57B,ATN1,MAMLD1,DNAJB6,ABCC5,DNM1L,GOLT1B,EDIL3,ATL1,SEMA3D,EGFR,ABI2,EIF4G2,COPS4,PAN3,DCTN4,USPL1,EN2,RCAN2,LRRC17,GPHN,ERBB4,SPEG,CDHR1,VPS26C,RTN3,SIRPB1,EZH1,NRN1,ZIC4,TAOK3,ATP8A1,STRADA,GORAB,SEC24B,PRKAG2,SCARA3,UBE2E3,HPCAL4,SYNCRIP,FOXO3,SEMA4D,FLT1,PSD2,SMC2,ZNF605,PRELID3A,CELF1,ST6GALNAC3,PNMA2,MEGF11,GAD1,FAM120B,GALC,IP6K3,C15orf41,ATP8A2,IGSF5,ALDH1L1,TUBA8,CYP46A1,NFU1,USP19,COPS8,SPIN1,GLS,ZNF638,GNG4,ATF7,GPER1,EML4,TMEM121B,STMN2,GRIA4,GRM1,GRM8,CLASRP,RNF165,COQ10A,MFSD2A,FAM107A,ADAMTS6,RASSF8,FRMD3,ARHGAP19,ZNF491,HNRNPK,AGFG1,LRRC75A,SHISA6,ICA1,IRF8,C5orf24,SCIN,ZNF678,KCND2,KCNH2,KCNMA1,KCNQ3,IPO5,LMO2,VWA5A,ASPRV1,MAP6,MAT2A,SYT9,CHIC1,TM6SF1,MEF2C,MEIS2,MITF,MMP16,MN1,JAKMIP3,MSR1,MT1M,CTNNA3,NBL1,NDP,NDUFA5,NEUROD1,NFIA,NHLH1,NINJ2,NME4,VWA2,OMG,OPA1,ZNF827,PAH,PAK3,PAX6,PCDHGC3,PCDH9,PCMT1,PCSK5,PDE4B,PIRT,ENPP2,PDYN,SLC10A4,BEST3,SEMA5B,CAMKV,PIK3R1,PKD1,PURG,PRIMPOL,MAPKAP1,EXOSC10,ING3,RETREG2,EPB41L4B,FAT3,POU3F2,MINDY2,PPM1B,PPP2R2B,CRLS1,PPP2R5C,PPP3CB,PRKAB2,PKIA,RAB39A,EPDR1,GRAMD1C,PRPH,MASP1,RELN,CNNM2,SAMD9,WBP1L,DEF8,PIGG,PTHLH,SPDL1,PTN,PTPN13,PTPRB,PTPRE,FAM120C,ACSM5,TTC13,TMEM255A,RAD51D,SH3TC2,NWD1,RASGRF1,ARID4A,RBBP6,KHDRBS2,BSDC1,ZYG11B,REV3L,PRRT2,GTDC1,RGS4,ARHGEF10L,RIT2,ALG9,PNMA8A,ELP2,CCDC102B,TMEM100,UEVLD,PRR5L,ACER3,ABCA11P,KCNIP3,ZNF568,TMEM156,DGLUCY,SAFB,ATXN1,ATXN2,ATXN7,LRRTM4,SCN7A,PRCD,SLC30A10,ZFP2,SEC14L1,SOX6,FOXRED1,TRA2B,SCAF8,SGK1,FRMPD1,ST6GAL1,URGCP,PREX2,DHX30,LRRC55,KDM4D,SLC8A2,CCDC88A,ATF7IP,SLN,GKAP1,SMARCC2,RIMS1,MBD5,KIF13A,SNRPN,SON,WDTC1,MYT1L,TNIK,IZUMO4,PEG10,DBNDD2,KIF1B,NFASC,TAB2,ATP10B,TROVE2,SMOC1,SSTR1,LRRC4,FCHO1,NEK4,SEPT8,CEP68,PHLDB1,VAMP1,FNDC9,DNAJC9,SYN1,SYN2,SYP,SYPL1,SYT4,MMS19,KAZN,MTCL1,CAMTA1,TAF9,TAL1,CAMSAP2,AGTPBP1,TBX15,VWC2,TCF4,TCF7,TCF7L2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,AHCYL2,PMS2CL,TMEM9,TLR4,ZFP91,ERCC6L2,HEY2,KCTD2,PIK3R5,TPD52,TPM1,SYNPO2,TRPC1,PPIL6,HIRA,UGT8,DNAJC12,MEAF6,BEST1,NSD2,WNT7A,XPO1,SF1,ZIC1,KCNT2,TRIM9,NDRG4,ZBTB38,REEP1,TMEM237,DPYSL5,EMSY,CADM2,PRDM2,PRDM10,LMAN2L,RNF103,CIAPIN1,NAV2,ITM2C,TRIM16L,C12orf4,RGS7BP,FZD3,DOCK8,VANGL2,NHSL1,FXR1,AP3B2,SOCS4,SLC4A10,SPATA13" MicroRNA hsa-miR-589*:mirSVR_highEffct hsa-miR-589*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-186 1.17E-182 3.89E-184 3.59E-183 460 1866 "DPF1,ABCF1,KCNH8,ABR,ASIC2,ACLY,ABHD6,NCKAP5,CCDC85A,GALNT13,AXIN2,SORCS1,ADRB2,KIDINS220,BEND6,INTS2,HECW2,KCTD16,OSBPL8,LRRC7,SPOP,ALCAM,FAM135A,LRFN1,DPP10,EP400,LCORL,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,UPRT,DGKD,ALS2,API5,USP37,MADD,TMEM263,ARRB2,TMEM108,STX16,N4BP2L1,RIPK1,SEC11C,DCAF5,BMP7,DST,IL33,CA12,CACNA1D,CACNB2,KALRN,PTBP2,CAMK2B,CAMK2G,SYT6,CAST,CBLN1,ZNF501,USP6,AIFM1,CBFA2T2,CD81,SEPT7,CDC27,CDC42,CDH10,MAGI1,CDO1,CCPG1,CLGN,RCBTB2,CHGA,JAM2,KMT2C,CLCN3,COG1,NIPBL,AKAP7,IQCK,ARMC8,SLC4A7,ABI3BP,COX4I1,AHCTF1,MYRIP,ZNF385A,CREM,RBM39,CS,SNCAIP,FEZ2,MICAL2,PLXNA4,ERC2,PHF14,CFAP61,PPP6R2,RUBCN,EDRF1,CYBB,DOCK4,HDAC9,FGFR1OP2,KIAA0513,ZFYVE16,ZNF337,RASSF2,LIN54,KCTD8,IST1,TOMM20,IP6K1,PABPC5,GIT2,ZEB2,ZBTB24,HP1BP3,ZC3H11A,RHOBTB1,NTM,WDR20,DLX1,GRIN3A,DMTF1,DPYSL2,GNE,ECM2,DYRK1A,ABCC9,E2F6,EDN1,ATL1,FAM13A,SUGP2,MBNL2,KMT5B,EIF4G1,STARD3NL,VPS13B,EPB41L1,LRRC17,EPHB1,KCNMB2,GPHN,RABEPK,ETV1,ANKMY1,EYA1,F3,ABCA8,NSRP1,DLC1,FCGR1A,CEP78,TESK2,ZNF589,FGF11,FGFR1,PRKAG2,SUCO,SLC37A3,USP16,PDLIM5,KHDRBS3,ST6GALNAC3,NSG1,PNMA2,NRG3,NEURL4,GABRA2,GABRA5,GABRG2,GAD1,GAD2,RAPGEF6,ARPP21,IQGAP2,C15orf41,DISC1,INPP5K,ACSS1,GCNT2,AHDC1,USP19,GHR,PPARGC1A,GK,RND1,SPIN1,GPR75,ZNF638,LUZP2,KCNMB4,CCDC184,B4GALNT4,EML4,TMEM121B,CECR2,PCLO,TUBA1C,RAPGEF4,GRB10,GRIA2,NR3C1,GRM1,RNF165,COQ10A,ZBTB49,MAEL,FRMD3,MIER3,VSIG4,HMGB1,HNRNPK,OPALIN,HSP90AA1,HTR2A,SOWAHA,C5orf24,IGFBP1,GAREM2,DOCK7,TJAP1,LIX1,KCND1,KCNJ9,KLHL23,KCNJ16,KCNMA1,KIF5A,KPNA5,STMN1,PAXBP1,HECTD2,FGFBP3,PACRG,SMAD1,MAP2,MAP4,MARK1,LYPLAL1,MAT2A,MBD1,SHC3,AFDN,MRPL42,ADAM22,MTR,MYCN,NAP1L1,NAP1L2,NASP,NEFM,NEFH,NF1,NFE2L2,ALDH1L2,CNOT4,NPPA,NPR2,NPTX2,NTRK2,NUCB2,IGSF11,OXTR,GPR137C,ZNF827,PAK3,PCDH9,PCMT1,PDE4D,ENPP2,PDYN,GPR85,GNG2,OLA1,CDK14,NLGN3,CCSER2,PLP1,PLXNB1,TRHDE,STRN3,LRP12,EXOSC10,MAGEL2,EPB41L4B,POLG,DRAM2,MED1,PPM1B,TATDN3,PPP3CA,PPP3CB,PRKCZ,HYDIN,RELN,CNNM2,NDUFS7,SAMD9,WBP1L,SIDT1,GON4L,SNRK,PIGG,PTCH1,BDNF-AS,TMEM260,PTPRB,PTPRO,ZNF615,USP47,RAP1GAP,SUSD4,NWD1,ZCWPW1,RASGRF2,VEPH1,MSANTD2,RDX,ERI2,GTDC1,RFX4,SEC61A2,SLC25A36,ZFHX4,ZNF532,C12orf49,CARF,GSTCD,ROBO1,CCDC25,RORB,ELP2,RPE,TMEM100,SPIN3,LRRK2,MEG3,SOX8,KCNIP1,CLIP1,TRAPPC13,AMER2,SAFB,SATB1,ATXN7,SCN8A,LINC00461,FNIP1,CASC3,NLGN4Y,ARX,CPEB3,FBXO11,ST6GAL1,NLGN1,SLC2A5,PEX26,SEPHS1,RAB3GAP1,ATF7IP,SLC22A4,SMARCE1,RCOR3,RIMS1,TMCC1,USP33,DOP1A,BDP1,DOK5,SP4,EMC1,HECW1,KDM4C,TEX2,PEG10,ZC3H13,NPAS3,CLSTN2,ITPRID2,SEPT8,STX1A,KANK1,GANAB,SYNE2,VPS13A,PLCB1,SYN2,ANKRD28,SYT4,MMS19,PJA1,DDHD2,CAMSAP2,FAM208A,ADGRL3,TBCEL,ZFP90,GPRIN3,DNAH7,PMS2CL,CRB1,ITGB3BP,AP4E1,TGFBR3,SLC44A1,TIAM1,ERCC6L2,PRRT1,KAT6B,TNS1,TPD52,TPM3,SYNPO2,METTL3,RUNDC3B,TRO,TSN,ANKRD20A2,CADM1,RPL7L1,SLAIN1,USP1,BEST1,WIPF1,KLC2,CLDND1,ZBTB14,ZNF24,MICU3,KCNT2,TRIM9,ZSCAN26,INTS3,EMSY,MFF,PRTFDC1,CSDE1,GDPD5,LINC02210,STOX2,ADAMTS9,HPS4,FIP1L1,ITM2C,WNK3,PDSS2,FAM13C,PAK5,HNRNPA3,PHTF2,CASC15,ACTR3B,ADAMTSL3,NLRP3,IFT88,FAM198A" MicroRNA hsa-miR-301a:mirSVR_highEffct hsa-miR-301a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.08E-186 2.85E-182 9.20E-184 8.47E-183 429 1623 "RALGAPA1,SDE2,CLK4,NCKAP5,ACTN2,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,BEND6,GPR158,HECW2,KLHL13,OSBPL1A,WDR35,HFM1,ADGRF5,SPARCL1,ALCAM,SRPX,ABCD2,FAM135A,MRTFA,LRCH2,LCORL,USP28,PHF12,APAF1,APBB1,APC,API5,AQP4,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,TMEM108,STX16,ATP2B1,ZNF582,ZNF583,N4BP2L1,NOL4,DPY19L3,ADAM23,TTLL9,TTC9B,ADGRB3,NRP2,DST,C5,CACNA1D,CALB1,CABP7,THSD7A,KALRN,CAMK2A,SYT6,CAST,MAP7,RUNX1T1,CERS5,USP6,SEPT7,TIGD7,CCPG1,CFL2,KMT2C,ZFYVE9,PLAA,TPP1,CLTC,TJP2,SRP14-AS1,NIPBL,AKAP7,ARMC8,FAM149A,BTF3L4,RCHY1,ACBD5,HS3ST5,CLOCK,CREM,GDA,CSF1,LRIG1,SIPA1L1,CHD5,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,HDAC9,FGFR1OP2,DCAF8,ZFYVE16,LONRF1,MATR3,DAPK1,SIRPA,SPATA2,YTHDC1,ZEB2,FBXL5,CEP170,DDX46,RHOBTB1,SPOCK3,NTM,WDR20,RAB39B,DPYSL2,DNAJB6,ABCC5,ABCC9,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,RBM12,KMT5B,EGR3,ASB3,CERCAM,PAN3,DCTN4,ENPP6,RABEPK,EPS8,TMEM74,TLR7,RASL12,F3,ABCA8,WAC,ACSL4,TESK2,GORAB,MED12L,FGF14,SEC23B,FOXF2,SYNCRIP,COQ5,JKAMP,NBEA,NPTN,NRG3,ZNF512,MEGF10,GABRA1,HBS1L,B4GALNT1,GAP43,ERAP1,TMEM8B,MYOZ2,ARFIP1,ADAM28,DBF4,RAB30,GLRB,GLS,TNRC6A,ZNF638,KDM2B,MAP7D2,INSM2,LUZP2,RAB40B,ZNF782,FERMT2,GPD2,PRUNE2,GPM6A,RAPGEF4,GRB10,GRIA2,SERP2,GRM1,GRM5,GRM7,ZNF496,CIT,LINC00839,RNF165,FAM222A,BACH2,HNF4G,HNMT,IRF8,MSL1,ZIC5,LRRCC1,USP54,LIX1,ZNF678,JAK1,CDH20,KCNJ11,KCNN3,CREG2,TTYH2,LIG4,LIMS1,ARHGAP12,MAP4,MATN3,MBNL1,MDM4,MEIS2,MOG,ERICH3,BCO1,MTR,LYRM9,ZNF862,MYT1,NAP1L1,NAP1L3,NDUFA5,NELL2,NEUROD1,NFIA,CNOT4,OCRL,GPR88,OMG,OPA1,OPHN1,GPR137C,PBX1,PCDH9,PCSK5,PDE1C,PDE3B,PDGFRA,PENK,PFKFB2,DUSP26,SERPINI1,CCSER2,ST8SIA5,JAKMIP1,PURG,LRP12,SLC36A4,POU3F2,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PSD,PLPPR1,MTMR10,PTHLH,STK32A,EML5,PTPRG,ZSCAN2,RAB5B,PID1,CEP97,RAD17,ATG16L1,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,RFX3,UBR7,SLC25A36,RPRD1A,C12orf49,KLHDC8A,CARF,ROBO2,EPHA10,BAALC,LRRK2,CNTNAP3,CLIP1,RTN1,ZNF354C,CCDC112,DGLUCY,SCN3A,FAM19A1,TNFRSF19,PEAR1,KIF21A,ARX,KIF16B,CHD9,SYBU,SEC31A,ZNF365,BTBD3,WDR47,RUFY2,KANSL3,SLC8A1,RAB3GAP1,CCDC88A,SHANK2,SLC14A1,BTBD7,NAXD,ZNF667,SNAP25,KIF13A,USP33,MYT1L,TRERF1,SOX5,DOK5,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,NUDT10,PLCB1,SYN2,ANKRD28,SYT4,ANKRD12,MTCL1,DDHD2,CAMTA1,CAMSAP2,FBXW11,PCDHB4,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,SIK3,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,TGFBR3,SLC44A1,GZF1,BHLHB9,ERCC6L2,TMOD1,TNFRSF1B,R3HDM1,CSMD1,TNS1,TPM3,STXBP4,TRPC3,TSC1,TUBB1,UBC,FAM155A,SLAIN1,BCL2L13,CCDC136,CCDC14,WRN,ZNF711,MICU3,TRIM9,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,SMARCAD1,SYNC,UPF3A,WNK1,PMEPA1,MAP3K12,MFF,LRP8,STOX2,KCNAB1,CAB39L,WNK3,PLSCR4,C12orf4,RGS7BP,DNAH10,UBE3B,CASC15,NHSL1,SLC39A12,FXR1,FRMD6" MicroRNA hsa-miR-802:mirSVR_highEffct hsa-miR-802:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-185 8.52E-182 2.66E-183 2.45E-182 467 1932 "CLK4,NDRG3,FMNL2,KLHL32,CCDC85A,AXIN2,SLC12A5,PWWP2A,KIAA1211,KIDINS220,DPY19L2P4,SLC44A5,PCDH19,TBC1D14,OSBPL8,HFM1,ALCAM,CEP126,BCAR3,FAM135A,AMPD3,DPP10,EP400,PPFIA1,APC,ALS2,APP,LGR5,MIER1,TMEM263,ZFYVE28,ARHGAP5,STK33,ZBTB10,TMEM108,ATP1A1,ATP1B3,ATP2B2,N4BP2L1,BACH1,BBS2,MPDZ,SEC11C,NRP2,CFLAR,DST,SGCE,WASF1,CA8,CACNA1B,PTBP2,CAMK2A,CANX,SLC25A14,MAP7,KRIT1,USP6,ZBED1,LGI1,L3MBTL4,CFL2,SRSF11,CHM,CHN1,JAM2,LSMEM2,LHX2,KMT2C,ZFYVE9,KIAA1549L,CLCN4,NMT2,CLTB,SULT4A1,HECTD1,NIPBL,CNN3,ARHGEF6,AKAP7,ARMC8,BTF3L4,AHCTF1,BAG4,ZNF521,IGDCC3,CP,CPS1,FAM171B,SEC31B,ENTPD4,CRMP1,ANKRD44,GDA,CSNK1G3,ATRNL1,PDE4DIP,PPP1R16B,ERC2,UBXN2A,PHF14,CTNND1,CTNND2,PUM1,ST18,RUBCN,EDRF1,CCDC144A,HDAC9,KATNAL2,FRMPD4,ZFYVE16,MATR3,KCTD8,DGKB,DBI,ZNF804A,HP1BP3,FBXL5,MAGI2,BLOC1S6,SNAP91,SV2A,SGSM2,G3BP2,WDR20,RAB39B,CPEB2,DMTF1,DPP6,PDCD6IP,GNE,ECM2,ABCC5,DNM1L,E2F5,EDN1,FAM135B,EDNRA,ANKRD46,RASGRP1,KLHL5,FRY,YAF2,CELSR3,PHF20L1,MBNL2,KMT5B,GOLGA7,ASB3,ELAVL2,RGS17,PAN3,DCTN4,USPL1,EPB41,KCNMB2,EPS8,EXTL2,F3,F5,CLVS1,FAM198B,WAC,ZNF585B,FABP7,SCML2,RACK1,GORAB,FGF1,FGF14,TMEM164,SCARA3,MEX3B,SEC23B,ATP13A4,SMC2,UFM1,ATP6V1H,DACH2,STAU2,MSANTD4,OGA,NEURL4,DKK3,CAB39,GAD1,ZNF274,IQGAP2,MTHFD2,C15orf41,DISC1,KIAA1841,MSTN,PPARGC1A,BRD8,TCERG1,DBF4,GLS,TNRC6A,ZNF638,RAB40B,ADGRA3,GPD2,PRUNE2,GPM6A,TDRKH,LILRA1,GPR19,LPAR4,DIDO1,GRIA4,RFFL,GRIK2,GRM7,GRM8,CIT,TMEM25,GSTT2,PSIP1,GUCY1B1,RASSF8,MIER3,VSIG4,ZNF491,HSP90AA1,SMAP1,SOWAHA,NKD1,RBPJ,TJAP1,SCIN,ZNF678,DIPK1A,LRRTM3,JAK1,KCNA4,KCNB1,KCNJ11,KCNK1,KCNN2,CAMK2N2,STMN1,PAXBP1,HECTD2,NCOA7,LSS,LYPLAL1,AQP11,MATN2,MEST,PPM1L,ZNF680,JAKMIP3,BLOC1S2,THYN1,MTR,MXI1,PABPC1L2A,NAP1L2,P2RY13,NCAM1,NDUFA5,NELL1,NEUROD1,NOS1,NPPA,NRCAM,SMIM11A,NUMA1,SETD4,CHAMP1,GLIPR1L2,PCDH9,PDE3B,SLC10A4,PENK,CDK14,NLGN3,ANLN,SNX10,KCTD15,FAM216A,PLIN1,PLP1,PCDH18,HMGCLL1,PMP2,MAPKAP1,STRN3,SCHIP1,MINDY2,PPP2R5E,PPP3CA,PPP3CB,PRKAB2,PRKACB,PKIA,MAPK9,HYDIN,SAMD9,VPS13C,PTCH1,PTK2,PTPN13,PTPRE,PTPRG,PTPRO,PTPRZ1,PTX3,ZSCAN2,CEP97,TMEM255A,ACSS3,RALGDS,FAT4,FAM184A,OXR1,ARID4A,RADX,KHDRBS2,SLC6A15,REV3L,FIGN,UBR7,SEC61A2,NUDT11,RNASEL,RPRD1A,ZFHX4,ALG9,ELP2,ACER3,MAP6D1,LRRK2,CNTNAP3,RPS20,RTN1,TRAPPC13,AP1AR,SATB1,ATXN7,HOGA1,SCN3A,LINC00461,CASC3,NLGN4Y,SGK1,CPEB3,MAGI3,NLGN1,NUBPL,WDR37,ZNF365,FAM81A,EPN2,RUFY2,KANSL3,SLC8A1,CCDC88A,SLC12A2,SLC14A1,NAPB,BTBD7,ZNF667,SORCS3,CDK5RAP2,SMARCE1,ANKRD36,MAPKBP1,SNRPN,PDZD2,SOX5,SP2,CLUAP1,ENKUR,MYCBP2,NPAS3,NFASC,SRPK2,CLASP2,TROVE2,COLGALT2,ELOVL4,DIP2A,SEPT3,FGD4,VPS13A,SYT4,C12orf76,MTCL1,PJA1,DDHD2,FAM208A,UNC5D,ADGRL3,KIAA1107,WWC1,AGTPBP1,TBCEL,FBXW11,TMEM136,ANO4,TCEA1,EHBP1,TCF4,DMXL2,SATB2,TCF7L2,TRIM2,RPGRIP1L,WASHC4,USP22,SYNE1,PCDHB15,PCDHB6,PUM2,TEK,FAM200B,DICER1,ZFPM2,HHIP,CDH22,SLC44A1,GZF1,TJP1,DDHD1,ERCC6L2,KAT6B,TPM2,C9orf85,NEIL2,PPIL6,ANKRD20A2,TSC1,RPL7L1,UBE3A,AMOT,UBTF,SLAIN1,VLDLR,ZNF781,WRN,RICTOR,SLC13A3,SF1,ZFP37,ZIC2,ZIC3,ZNF711,MICU3,LYPD6,CA10,STOX2,ADAMTS9,SCG2,PCDH15,KCNAB1,FAM47E,PDSS2,GOPC,DOCK8,PAK5,SMIM8,PHTF2,JMJD1C,SSPN,NETO2" MicroRNA hsa-miR-380:mirSVR_highEffct hsa-miR-380:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.63E-185 3.16E-181 9.30E-183 8.57E-182 468 1946 "SERPINA3,ACADM,CSMD2,FMNL2,DSCAML1,RNF157,ADD3,GRAMD1B,PWWP2A,KIAA1211,ESYT2,KIDINS220,ZNF608,PCDH19,HACE1,OSBPL1A,KIAA1324,OSBPL8,CC2D2A,ADGRF5,LRRC7,SMIM17,DOC2A,CDC42BPA,LRCH2,ANK3,APAF1,APC,MAGEE2,ALS2,DDO,API5,APP,SHTN1,TMEM263,ARHGAP5,ASTN1,ATP1A2,SLC4A4,N4BP2L1,DPY19L3,ADAM23,BACH1,ADGRB3,LINC00847,MPDZ,NRP2,DST,MTMR2,SGCE,WASF1,IL33,CACNA1B,THSD7A,KALRN,TRIM41,CANX,PRC1,CLDN10,KRIT1,METTL6,CDH10,ZMYM4,LRRFIP1,MAGI1,CCPG1,CLGN,CFL2,RCBTB2,CHGB,MS4A7,B4GALT6,NDST3,NRXN1,ARMC8,FAM149A,AKAP6,SLC4A7,ABI3BP,MFSD4A,FAM171B,C2CD2,CREM,HAPLN1,ANKRD44,SNCAIP,CSF2RA,CSNK1G3,SIPA1L1,UBXN2A,PUM1,CCDC144A,DOCK4,ARHGAP32,RIPOR2,DCAF8,FRMPD4,ZFYVE16,KCTD8,DGKB,DAPK1,SCRN1,PABPC5,ZEB2,MYEF2,TIAM2,HP1BP3,FBXL5,RHOBTB1,SRGAP3,RABGAP1L,WDR20,ZNF582-AS1,GRIN3A,RAB39B,DMD,NR1D2,CDON,DPYSL2,ABI1,GNE,DTNA,ECM2,ABCC9,GOLT1B,AASDH,EDIL3,EDN3,EDNRB,SEMA3D,KLHL5,FSD1L,PHF20L1,MBNL2,EIF4G2,ELAVL4,PCOLCE2,EML1,VPS13B,EPB41L1,EPHA5,CEP85L,ETV1,ADGRV1,F3,CLVS1,FAM198B,ZNF461,ACSL4,ATP8A1,FCGR1A,GORAB,SLC9B2,GTF2IRD2,FGFR1,FGFR3,FHL1,POLK,SUCO,MEX3B,IP6K2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,PSD2,SLC37A3,C2orf88,JKAMP,SMC2,ATP6V1H,DACH2,MSANTD4,OGA,STAG2,GABRA1,GABRA2,GALNT15,GABRB3,GAD1,ZNF274,MTHFD2,SYT17,C15orf41,DISC1,LRRC37A6P,MYOZ2,IGSF5,SULT1C4,MSTN,MALT1,GK,ZNF276,RND1,TXNL4A,RNPS1,GLRB,ADGRA3,GPD2,GPM6A,FUT10,LILRA1,STON1,PCLO,DIDO1,BTN2A1,KIF3A,CLASRP,BVES,LINC01551,RABL2A,ATXN2L,HMGCR,IGFBP1,LRRCC1,LIX1,ZNF678,DIPK1A,LRRTM3,ITGAV,JAK2,KCNA4,KCND2,KCNJ3,KCNJ16,KIF2A,STXBP5,LAMP2,LIG4,HECTD2,NCOA7,AQP11,MBNL1,ADAM11,MEF2C,MEIS2,KITLG,WDR49,ZNF680,MRPL42,BLOC1S2,ADAM22,SCG3,ZNF92,CTNNA3,MYO9A,NAP1L1,NAP1L2,NDUFA5,NF1,NHLH1,CNOT4,HCN1,NTRK2,NUCB2,ZNF713,P2RX7,GPR137C,KCNK10,GLIPR1L2,CNTN3,PCDH8,PCMT1,PCSK2,PDE4D,ZDHHC8,GPSM2,PMP2,PMP22,LRP12,SH3KBP1,PPM1B,PRKACB,CEP41,RAB39A,GRAMD1C,DIRAS2,RELN,VPS13C,GON4L,SNRK,CNTLN,ANKHD1,PTHLH,TMEM260,STK32A,OCIAD1,PTPRD,PTPRE,PTPRG,TMEM255A,RAD17,ZCWPW1,DBX2,RBBP6,RADX,KHDRBS2,RDX,SLC6A15,ZYG11B,ERI2,FIGN,RFX3,UBR7,SLC25A36,RIC8B,RPRD1A,ZFHX4,CCDC82,DCUN1D2,CARF,ROBO1,CCDC102B,TMEM100,ADAL,ACER3,LRRK2,ZNF331,AP1AR,SATB1,CSRNP3,SCN2A,FAM19A1,LINC00461,FNIP1,HES6,ELMOD1,IL17RB,SGK1,ZFP30,KIF21A,ITSN1,SH3GL2,SH3GL3,CPEB3,SHC4,CHD9,FNDC3A,NLGN1,ZNF365,PREX2,DHX30,WDR47,SLC6A1,KANSL3,SEPHS1,SLC8A1,RADIL,SLC8A3,CCDC88A,SLC12A2,SPHKAP,SORCS3,SMARCE1,RCOR3,SNAP25,LMBRD1,UNC80,RBM34,SP4,ENKUR,UHRF1BP1L,MYCBP2,KDM4C,PEG10,ZNF423,ZC3H13,CDK19,RBM26,LMO3,ATP10B,CLASP2,ZNF302,EPB41L3,LARP4,ERBIN,MAPK8IP3,STAU1,CEP68,TTBK2,RGL1,PRRC2C,ADAMTS17,PLCB1,SYN2,SYPL1,SYT4,TACC1,KAZN,EXOC7,ADGRL3,AGTPBP1,FBXW11,KLHL4,SATB2,TCF7L2,ZEB1,TCF12,WDR7,SYNE1,DOCK9,PCDHB7,PUM2,FRYL,AHCYL2,DICER1,ITGB3BP,HHIP,CSMD1,TPD52,C9orf85,TPM4,STXBP4,TRPC3,TRPS1,ZMYND8,DCBLD1,TMEFF2,SGK3,HEPACAM,CADM1,UBE3A,FRRS1L,UGT8,SLAIN1,PITPNB,PLEKHH2,USP1,VSNL1,ZNF781,XRCC4,ZFP37,ZNF708,KCNT2,AGMO,LYPD6,TCEAL7,REEP1,SPIRE1,SMARCAD1,SYNC,EMSY,PRDM2,LRP8,CSDE1,EVI5,LINC02210,STOX2,RNF103,ADAMTS9,MDH1B,FAM47E,MPPE1,RGS7BP,FAM13C,RTN4,HNRNPA3,PHTF2,FBXO36,JMJD1C,RNF170,SSPN,KLHDC1,FXR1,FRMD6,NETO2,NETO1,SENP7" MicroRNA hsa-miR-630:mirSVR_lowEffct hsa-miR-630:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.63E-185 3.16E-181 9.30E-183 8.57E-182 468 1946 "CLK4,KDM5D,CSMD2,ARID1A,FMNL2,PLEKHG5,TMEM132B,GALNT16,GALNT13,ADD1,KIAA1211,BEND6,SLC24A4,AP2A2,GPR158,HECW2,WDR35,TXNDC16,CC2D2A,AK2,HFM1,ADGRF5,LRRC7,ALAD,ALCAM,CEP126,ARHGAP20,PCDH10,UNC79,USP28,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,APAF1,APBB2,APC,EPB41L5,GPAM,VAT1L,USP37,SHTN1,SHROOM2,ARHGAP5,ARNTL,RGS20,PLA2G4C,ASPA,ASPH,NUMB,ATM,ATP1A2,ATP2A2,RNF182,CARMIL3,BACH1,LINC00847,BBS2,MPDZ,BCL2L2,BCL7A,DCAF5,GPR146,DST,ST3GAL5,SYNJ2,ARHGEF7,NAE1,NIPA1,CALB1,PTBP2,VXN,VSTM2A,RUNX1T1,METTL6,USP2,CDC42,CDH8,ZMYM4,CLGN,NPIPA1,SRSF11,CHN2,JAM2,SLIT2,LHX2,KMT2C,NRXN3,PLAA,NRXN1,CLTA,FBXO7,DNAJB5,QKI,LY86,NIPBL,TMEM155,CNTN1,AKAP7,ARMC8,FAM149A,AKAP5,ABI3BP,RCHY1,RTTN,ZFP28,CPS1,CREM,RBM39,CSF2RA,ARHGEF10,SUSD5,ATRNL1,IPCEF1,UBXN2A,PHF14,RIMS2,FGFR1OP2,MATR3,KIAA0586,KCTD8,DGKB,AIF1L,ARMCX4,PITPNC1,SPATA2,DGCR5,MFAP3L,CEP170,BLOC1S6,FBXO25,RABGAP1L,MTX3,WDR20,EXOG,RAB39B,DNAH9,DMTF1,ARRDC4,DTNA,DNAJB6,DNM1L,E2F5,E2F6,WDPCP,FAM135B,EDNRB,ATL1,ANKRD46,TMTC1,MBNL2,EIF4G2,EIF5,PAN3,EPHA5,KCNMB2,ANKRD13B,SRRM1,KATNAL1,EZH1,FAM198B,ZNF461,FABP7,RPS6KC1,ACSL4,ZIC4,ATP8A1,FCGR1A,CEP78,FECH,SEC24B,POLR1B,FGF11,CAMSAP1,SUCO,SCARA3,CAP2,IP6K2,PCYOX1,SYNCRIP,EVL,SEMA4D,ANKFY1,SMC2,UFM1,ARFGAP2,ZNF605,KHDRBS3,ST6GALNAC3,NRG3,PHYHIPL,DKK3,GAB1,GABRA5,GALNT15,GABRG1,GAD1,FAM120B,GALC,RAPGEF6,NCKAP1,DNER,GCNT2,MSTN,GDF9,MMADHC,GHR,GK,DBF4,TOX3,GLUL,HTATSF1,LUZP2,FERMT2,GPM6B,TDRKH,GPR37,RAPGEF4,GRIA4,GRIK1,GRIK2,GRM3,GRM7,CLASRP,FAM19A2,TMEM25,ZBTB49,IRAK3,HAS2,PADI2,DDX19B,SYNPO,HPCA,USP51,TCEAL6,IDH3A,LINC00667,C5orf24,GAREM2,RBPJ,KIAA1755,SCIN,ZNF678,ZNF385B,ITGAV,KCNA4,KCNA6,KCNC2,KCNK1,KCNMA1,KCNN2,KHK,KIF5C,IPO5,STXBP5,CYP27C1,SYTL4,ARHGAP12,GPR155,MAP2,MARK1,MARK3,MBNL1,SYT9,CHIC1,TM6SF1,MEIS1,AFF1,MOG,MPP2,ZNF680,LAYN,MYO9A,NCAM1,NEK1,NFE2L2,NUCB2,CNTN3,PRTG,PDE2A,PDE3B,PDE4D,PIRT,PDGFRA,NLGN3,NALCN,PLCL1,PCDH18,MTRF1L,TRHDE,STRN3,PRRX1,EPB41L4B,SLC36A4,FA2H,POU3F2,CCDC144B,PPP2R2B,LRRN3,CRLS1,PPP2R5C,RANBP3L,PRKACB,PKN2,LRRC49,SYTL2,CNTLN,PLPPR1,PTK2,SPDL1,ZIK1,PTPRB,OCIAD1,PTPRE,FAM120C,PEX5,TTC13,TUG1,CCDC40,PLEKHB2,RAD52,SH3TC2,DBX2,REV3L,RGS4,RGS10,RIT2,EXD2,ROBO2,TMEM100,NEK11,ARMH4,RPS20,CLIP1,CCDC112,TRAPPC13,SAFB,SCN3A,LRRTM4,SCP2,IL17RB,SOX6,SELL,RASA3,SCAF8,KIF21A,SH3GL3,FERMT1,FBXO11,FNDC3A,ST8SIA1,DZIP1,ANKRD6,ZNF365,RPH3A,SLC2A5,FAM214B,CCDC88A,SLC12A2,ELMO2,ZNF667,SORCS3,SMARCD3,SMARCE1,RCOR3,PDZRN3,UNC80,USP33,SON,PDZD2,SOX2,SP4,SPP1,IDI2-AS1,KIF1B,ZBTB43,MCF2L2,NPAS3,C11orf87,SRPK2,PBLD,STOX1,ZC4H2,SS18,ADHFE1,STX1A,GSE1,SYT11,NUDT10,FNDC9,ANKRD28,POPDC3,TAC3,TAF9,AGTPBP1,ANO4,TCEA1,SIN3B,DMXL2,SATB2,TCF7,TCF7L2,ZEB1,WDR7,DOCK9,RALYL,SLC19A3,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,PMS2CL,CRB1,SLC44A1,NR2E1,DAAM2,KCTD2,R3HDM1,CSMD1,C9orf85,DOK6,PRMT8,PDSS1,TRO,STXBP4,TRPC1,ANO5,TTTY15,ZKSCAN5,TMEFF2,HIRA,RPRM,FAM155A,FRRS1L,WIPF1,NSD2,XRCC4,CFAP52,TRIM9,MKRN3,ZSCAN26,PLPPR5,ZFAND5,WNK1,SLC30A4,EMSY,PRTFDC1,SLC38A1,CSDE1,HPS4,MDH1B,PPP1R3F,FAM47E,WNK2,FZD3,KAT6A,NUP214,ACTR3B,TIGD6,SSPN,FXR1,CBLN2,FAM181A" MicroRNA hsa-miR-520f:mirSVR_lowEffct hsa-miR-520f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.81E-185 5.51E-181 1.57E-182 1.45E-181 450 1801 "ACTN1,CSMD3,ADARB2,GALNT16,ADCY2,ADCY5,ADCY6,RNF157,ADD1,SORCS1,ESYT2,FAHD2CP,NLGN4X,SLC24A4,GPR158,KCTD16,OSBPL1A,OSBPL8,LRRC7,SPOP,ARHGAP20,PCDH10,PDZD4,AMPD3,ANK3,C6orf89,LCORL,PPFIA1,GPAM,PPP4R4,IGDCC4,SPTBN4,RGS20,ARSF,CAPRIN2,NUMB,INSYN2B,EIF4G3,STX16,ATP2B2,RNF182,MYOM1,TTLL9,ADGRB3,MPDZ,BCHE,NRP2,PROM1,KSR1,DST,SYNJ1,ARHGEF7,SGCE,MYRF,CFAP410,CACNB2,CALB1,KALRN,SLC25A14,P2RX6,AIFM1,SCARB1,DGKI,DCLK1,LOC730101,SRSF11,MS4A7,SYNPR,B4GALT6,NRXN3,DNAJB5,C4orf33,LY86,NIPBL,BTF3L4,SLC4A7,RCHY1,IFFO1,COX4I1,SMARCAL1,MYRIP,MFSD4A,SLC35F1,FAM171B,C2CD2,CREB5,ANKRD44,GDA,CRYM,SNCAIP,RGS6,ARHGEF10,OSBPL3,VAC14-AS1,PDE4DIP,CNTNAP2,FAM169A,CFAP61,NRSN1,BOC,HDAC9,RIPOR2,EARS2,RASSF2,LIN54,INTS1,DGKB,TMEM170A,BRINP1,AIF1L,SIRPA,DBN1,JAKMIP2,C8orf34,SPOCK3,SRGAP3,WDR20,CCDC3,DLG3,DLX1,EXOG,GRIN3A,USP3,DYNC1I1,DOCK2,DMTF1,DTNB,MAMLD1,DNAJB6,DNM1L,E2F5,EBF1,EDNRA,ATL1,HIPK3,TMTC1,SH3GLB1,PHF20L1,EGFR,MRO,ELAVL2,RGS17,CALCRL,PAN3,RCAN2,LRRC17,MTSS1L,ANKRD13B,DUSP27,CD320,EZH1,ZNF461,ATP8A1,RACK1,FDFT1,FGF13,FGR,SUCO,SEMA4D,FLT1,ANKFY1,C2orf88,DPYSL4,NBEA,ZBED3,APOPT1,ARFGAP2,ZNF605,CELF1,DACH2,ST6GALNAC3,MSANTD4,NRG3,DKK3,GAB1,GABRA2,GABRA5,NCKAP1,GATM,ALDH1L1,ADAM28,PPARGC1A,MALT1,COPS8,GLI2,GLS,TOX3,ZNF638,DCLK2,GNAS,FERMT2,PRUNE2,GPM6A,NUDT21,PCLO,GRIA1,GRIA2,GRID1,GRIK2,ADAMTS13,RNF165,ZBTB49,BVES,MFSD2A,SOX21,PSIP1,RASSF8,HPS5,PTGDR2,MAN1B1,ARHGAP19,TNFAIP8L3,BACH2,HNF4G,HSF2,HSP90AA1,ZIC5,PLD5,USP54,BRINP3,ITPKB,KCNJ3,KCNK2,KTN1,INSYN2,PAXBP1,HECTD2,C2orf80,ZNF667-AS1,MAP2,MAP4,MAT2A,MBNL1,CHIC1,LDLRAD3,MDM4,LRP1B,PPM1L,MKLN1,MOBP,MOG,ERICH3,SESN3,SCG3,MTR,RSPO2,RTL5,NDUFA5,CCDC13,NEK1,NF1,NFIA,NFE2L2,NFYA,NPTX1,PCBP3,HCN1,NTRK2,DDR2,OCRL,ODF2,OMG,OPCML,OPHN1,P2RY1,KCNK10,SNTG1,PAX6,DPY19L2P2,PCDH8,PIRT,OLA1,PFKP,CDK14,ZDHHC8,SERPINI1,XRN1,GPSM2,FAM216A,PLCL1,SLC25A23,SPATA6,FA2H,FAT3,NXPH1,DRAM2,TMEM235,CCDC144B,CRLS1,PPP2R5C,PPP2R5E,RASGEF1B,PRKACB,PRKCZ,MAPK9,MAPK10,SLC22A23,APTX,SIDT1,GON4L,QRICH1,WDR25,PTHLH,PXK,PTN,ZSCAN32,PTPRB,PTPRD,FAM120C,NKAIN1,TUG1,RAD52,OXR1,MSANTD2,ZYG11B,RFX4,ARHGEF10L,PBRM1,LGI2,CCDC82,ZNF532,C12orf49,ALG9,ROBO1,ROBO2,TMEM100,NEK11,RPL15,UEVLD,ATP8B4,ACER3,LGR4,SALL1,SEMA6D,ATXN2,HOGA1,SMPD3,SOX6,SUPT20H,ITSN1,SHC4,FHOD3,SLC1A3,SLC1A6,SLC6A1,LRRC55,SLC6A9,CCDC88A,SLC11A1,SLC12A2,SLCO1A2,SLC22A4,ZFP1,SMARCD3,INTS9,SMARCE1,ANKRD36,INAVA,MBD5,SNRPN,FAM126B,SON,PDZD2,SOX5,ENKUR,BEX1,SPTAN1,NPAS3,C11orf87,TAB2,NKAIN2,LRRC4,ZSCAN29,CEP68,DIP2A,GSE1,SYNE2,VAMP1,ARHGEF9,VPS13A,PLCB1,COBL,TAC1,DDHD2,EHBP1,TRIM2,RPGRIP1L,SZT2,WDR7,SYNE1,RALYL,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,PMS2CL,CRB1,C18orf54,ZNF106,HHIP,AKTIP,TIAM1,ACTR6,HEY2,RIMBP2,TNS1,PIK3R5,RBFOX2,CHST5,NR2C2,METTL3,TRIO,TRPS1,TUB,TMEFF2,UBE2H,BEST1,KLC2,RICTOR,ZFP37,FMN2,ZBTB16,TMEM237,UPF3A,CA10,SLC30A4,EMSY,CADM2,DNALI1,GDPD5,LINC02210,RNF103,SCG2,HPS4,NAV3,SLC17A7,FAM47E,WIPF2,WNK2,SLC17A6,ACTR3B,JMJD1C,TIGD6,VANGL2,NETO2,CPNE4" MicroRNA hsa-miR-3161:mirSVR_lowEffct hsa-miR-3161:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-184 9.45E-181 2.58E-182 2.37E-181 444 1755 "CLK4,ACTN2,KDM5D,XKR4,ADCY2,KLRC4,CCDC85A,GALNT13,SLC12A5,PWWP2A,KIDINS220,SLC44A5,ZNF608,INTS2,HECW2,OSBPL1A,OSBPL8,CC2D2A,TAOK1,LRRC7,SEMA6A,SPOP,ALCAM,FAM135A,MRTFA,ANK2,CCDC146,LCORL,MAP4K3,USP28,PPFIA1,ANXA7,APBA2,APC,VAT1L,TNRC6C,USP37,APP,AQP4,TMEM263,RGS20,CADPS,CAPRIN2,ZBTB10,NUMB,ATP1A3,ATP2B2,ATP2B3,N4BP2L1,NOL4,ADAM23,CFLAR,DST,SYNJ1,NIPA1,OSGIN2,IL33,CA8,PTBP2,VSTM2A,CAST,SPAG9,ZNF501,TMEM257,CDH8,DCLK1,CLGN,NOG,SRSF11,SYNPR,KMT2C,RAB33A,CLTB,TJP2,QKI,TMEM184B,FHL5,CNN3,CNR1,FAM149A,SLC25A27,COL9A1,RCHY1,AHCTF1,ACBD5,ZNF521,HS3ST5,CPS1,CLOCK,NCOR2,SNCAIP,FEZ2,SUSD5,ATRNL1,CNTNAP2,FAM169A,PPP1R16B,UBXN2A,RIMS2,GPSM1,USP6NL,CYBB,DOCK4,KATNAL2,ARHGAP24,DCAF8,TM9SF4,MATR3,KIAA0586,KCTD8,MAML1,TOMM20,ZNF804A,C8orf34,KIAA0753,MAGI2,FBXO25,GSDME,SMG7,SPOCK3,NTM,MTX3,SEC16A,ZNF582-AS1,GRIN3A,RAB39B,DMD,DNM1,CDON,DRD1,PDCD6IP,ARRDC4,DTNA,GOLT1B,E2F5,EDNRB,ATL1,SYT15,RASGRP1,SEMA3D,SH3GLB1,EGFR,MBNL2,ASB3,KCTD3,EIF4G2,DCTN4,EMX2,LRRC17,EPHA5,ENPP6,GPHN,EPS8,TMEM74,ETV1,F5,FABP7,DLC1,CHST15,TOMM40L,ZSCAN30,TESK2,PPP1R1B,GORAB,SEC24B,MED12L,GTF2IRD2,FGF12,POLK,HPCAL4,SYNCRIP,FLT1,SLC37A3,C2orf88,EFCAB2,ZCCHC17,CELF1,DACH2,STAU2,AP4B1,DOT1L,GAB1,GABRA1,GALNT15,GABRB3,ZMYND11,GALC,SALL3,NCKAP1,IQGAP2,MTHFD2,MSTN,GFAP,ADAM28,GK,TCERG1,SPIN1,GLS,PCDH11X,MAP7D2,FERMT2,LNX1,CNDP1,PRUNE2,GPM6B,ATF7,TDRKH,FUT10,LPAR4,GPR34,NUDT21,TMEM121B,PCLO,CNTRL,GRIA2,GRIA4,GRIK2,PRDM5,LINC00839,COQ10A,KAT7,PSIP1,GUCY1B1,IRAK3,RASSF8,NXPH2,GABARAPL2,HNMT,C9orf129,OPALIN,LINC00667,ZNF546,DOCK7,IL6ST,IL12A,KCNA1,KCNA4,KCNC2,KIF5C,KIFC3,HECTD2,FGFBP3,NCOA7,ASPRV1,SMAD1,MARK1,LYPLAL1,MBNL1,KCTD6,POC1B,MITF,MOG,MPP2,BLOC1S2,ZNF92,MXI1,MYCN,RTL5,NAP1L1,NCAM1,NEUROD1,SLC11A2,NTRK2,NUCB2,ODF2,CHAMP1,PAH,GLIPR1L2,PCMT1,PCSK1,CDK18,PRTG,PDE4B,PIRT,PFKP,SERPINI1,FAM218A,CCSER2,RETREG1,XRN1,PLCL1,PLP1,PCDH18,HMGCLL1,STRN3,PSAT1,PRRX1,SEPT4,SLC36A4,NXPH1,DRAM2,MED1,PPP2R5E,RANBP3L,PRKACB,PRKCB,RAB39A,RELN,SLC22A23,SYTL2,GON4L,ANKHD1,PLPPR1,BDNF-AS,PXK,TMEM260,PTPN13,OCIAD1,PTPRZ1,RAD52,ZNF793,OXR1,RASGRF2,ARID4A,BSDC1,RDX,SLC6A15,REV3L,SEC61A2,PBRM1,ZFHX4,CARF,GSTCD,NEK11,UEVLD,FBXW7,BAALC,ZC3H14,ACER3,ABCA11P,RTKN,MAPK12,SCN2A,SCN4B,LINC00461,PRCD,CASC3,SCAF8,SH3BGR,SH3GL2,PPM1E,BCAN,NUBPL,SLC2A5,EPN2,RUFY2,RAB3GAP1,KBTBD4,NAPB,SLC15A2,RCOR3,LIMCH1,MBD5,SNRPN,UNC80,USP33,SON,MYT1L,TNIK,HECW1,IDI2-AS1,PEG10,NPAS3,C11orf87,SRPK2,ATP10B,CLSTN2,ITPRID2,NKAIN2,ERBIN,ST5,STAU1,ZSCAN29,SEPT8,NECAB1,PRRC2C,SYT1,COBL,ANKRD28,DDHD2,UNC5D,TMEM136,SMG6,KLHL4,MGRN1,TBX15,SATB2,TRIM2,RPGRIP1L,WASHC4,WDR7,PCDHGA11,PCDHB4,TNS2,FRYL,HIF3A,SIK3,ZMAT3,AKTIP,TIAM1,TMEM9,TLR4,NR2E1,SEZ6L,RGMB,NR2C2,ZNF346,TRPC3,TRPS1,ZMYND8,SSBP2,UBE3A,PITPNB,NSD2,WRN,XRCC4,PCDH20,ZIC3,MICU3,ZNF32,AGMO,FMN2,LYPD6,POLR3H,ZNF195,CADM2,PRDM2,DNALI1,CSDE1,RNF103,WIPF2,PLSCR4,PDSS2,FAM13C,FZD3,DOCK8,PAK5,PHTF2,ADAMTSL3,ZNF248,NHSL1,SLC39A12,CPNE4,PRRT4" MicroRNA hsa-miR-301b:mirSVR_highEffct hsa-miR-301b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.70E-184 9.53E-181 2.58E-182 2.37E-181 427 1621 "RALGAPA1,CLK4,NCKAP5,ACTN2,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,BEND6,DPY19L2P4,GPR158,HECW2,KLHL13,OSBPL1A,WDR35,HFM1,SPARCL1,ALCAM,SRPX,FAM135A,MRTFA,LRCH2,LCORL,USP28,APAF1,APBB1,APC,API5,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,STX16,ATP2B1,ZNF582,ZNF583,N4BP2L1,NOL4,DPY19L3,ADAM23,TTLL9,TTC9B,BACH1,ADGRB3,NRP2,DST,SYNJ2,C5,CACNA1D,CALB1,CABP7,THSD7A,KALRN,SYT6,CAST,MAP7,RUNX1T1,USP6,SEPT7,TIGD7,CCPG1,CFL2,KMT2C,ZFYVE9,PLAA,CLTC,SRP14-AS1,NIPBL,FHL5,AKAP7,ARMC8,FAM149A,BTF3L4,RCHY1,ACBD5,HS3ST5,CLOCK,CREM,RNF14,GDA,CSF1,LRIG1,CHD5,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,HDAC9,FGFR1OP2,DCAF8,LONRF1,SIRPA,SPATA2,YTHDC1,ELMSAN1,ZEB2,HP1BP3,FBXL5,CEP170,DDX46,RHOBTB1,SPOCK3,NTM,WDR20,RAB39B,DYNC1I1,CPEB2,DPYSL2,DNAJB6,ABCC5,DNM1L,ABCC9,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,RBM12,KMT5B,EGR3,ASB3,CERCAM,PAN3,RCAN2,ENPP6,RABEPK,EPS8,TMEM74,TLR7,RASL12,F3,ABCA8,ACSL4,TESK2,GORAB,MED12L,FGF11,FGF13,FGF14,SEC23B,FOXF2,SYNCRIP,RGPD5,ATP13A4,FLT1,COQ5,JKAMP,NBEA,TACC2,NPTN,ZNF512,MEGF10,GABRA1,HBS1L,B4GALNT1,ZNF274,GAP43,ERAP1,MYOZ2,ARFIP1,SESN1,ADAM28,DBF4,RAB30,GLRB,GLS,TNRC6A,KDM2B,MAP7D2,INSM2,LUZP2,RAB40B,GPD2,PRUNE2,GPM6A,RAPGEF4,GRB10,GRIA2,SERP2,GRM5,GRM7,ZNF496,CIT,LINC00839,RNF165,HNF4G,HNMT,IRF8,MSL1,ZIC5,LRRCC1,USP54,LIX1,ZNF678,JAK1,CDH20,KCNN3,CREG2,IPO5,TTYH2,LIG4,LIMS1,ARHGAP12,MAP4,MATN3,MBNL1,MDM4,MEIS2,MOG,ERICH3,BCO1,MTR,LYRM9,ZNF862,MYT1,NAP1L1,NAP1L3,NDUFA5,NELL2,NEUROD1,NFE2L2,CNOT4,OCRL,GPR88,OMG,OPA1,OPHN1,P2RX7,GPR137C,PBX1,DPY19L2P2,PCDH9,PCSK5,PDE1C,PDE3B,PDGFRA,PFKFB2,DUSP26,SERPINI1,CCSER2,ST8SIA5,JAKMIP1,PURG,PMP2,MAPKAP1,LRP12,POU3F2,PPP1R1A,CRLS1,PPP2R5E,PPP3CA,PPP3CB,KANSL1,PRKACB,PSD,PLPPR1,MTMR10,PTHLH,STK32A,EML5,PTPRG,ZSCAN2,RAB5B,PID1,CEP97,RAD17,ATG16L1,RASGRF2,ARID4A,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,UBR7,SLC25A36,RPRD1A,KLHDC8A,CARF,ROBO2,EPHA10,BAALC,LRRK2,CNTNAP3,CLIP1,RTN1,ZNF354C,CCDC112,DGLUCY,LRFN5,SCN3A,FAM19A1,TNFRSF19,PEAR1,KIF21A,ARX,KIF16B,MAGI3,CHD9,FBXO11,SYBU,ZNF365,BTBD3,WDR47,RUFY2,KANSL3,SEPHS1,SLC8A1,RAB3GAP1,CCDC88A,SHANK2,SLC14A1,BTBD7,NAXD,ZNF667,SNAP25,KIF13A,USP33,MYT1L,TRERF1,SOX5,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,NUDT10,PLCB1,SYN2,ANKRD28,SYT4,ANKRD12,MTCL1,DDHD2,CAMTA1,CAMSAP2,FBXW11,ATMIN,PCDHB4,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,SLC44A1,BHLHB9,ERCC6L2,TNFRSF1B,R3HDM1,CSMD1,TNS1,TPM3,STXBP4,TRPC3,TSC1,RFTN2,UBC,RPL7L1,FAM155A,AMOT,SLAIN1,CCDC14,WRN,ZNF711,TRIM9,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,SMARCAD1,SYNC,UPF3A,WNK1,PMEPA1,MAP3K12,MFF,LRP8,STOX2,KCNAB1,CAB39L,WNK3,PLSCR4,C12orf4,RGS7BP,DNAH10,UBE3B,NHSL1,SLC39A12,FXR1,FRMD6" MicroRNA hsa-miR-130b:mirSVR_lowEffct hsa-miR-130b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.31E-184 4.11E-180 1.08E-181 9.96E-181 443 1753 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,PWWP2A,AK2,ADGRF5,LRRC7,BCAR3,PCDH10,PITPNM2,AMPD3,ZFAT,OGT,SEMA7A,CCDC146,MAP4K3,PPFIA2,APBB2,APC,EPB41L5,TNRC6C,SHTN1,ARHGAP5,ASCL1,ATP1A2,SLC4A4,ZNF582,MTMR9,B3GALT2,DOCK11,KSR1,BMPR1B,SGCE,NIPA1,LDLRAD4,BTRC,CALB1,NGB,CAMK2D,CAMK2G,TRIM41,CANX,VSTM2A,SPAG9,RUNX1T1,USP2,CBFA2T2,REPS2,CDC42,CDH2,DCLK1,MAGI1,NOG,CACNA2D2,SRSF11,FOXN3,MS4A7,SYNPR,CLCN4,COG1,FBXO7,C4orf33,QKI,HECTD1,IQCK,SLC25A27,SLC4A7,SLC4A8,BAG4,ZNF521,CREB5,HAPLN1,CRY2,FEZ2,MICAL2,SIPA1L1,FAM169A,DZIP3,KIAA0040,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,DAPK1,IP6K1,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,ELMO1,MFAP3L,MAGI2,KLHL3,SNAP91,SV2B,NTM,G3BP2,FAM107B,KBTBD11,DLG2,DLG3,GRIN3A,NYAP1,USP3,DNAH9,MED12,DNM2,SLC12A6,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,HIPK3,TMTC1,FRY,FAM13A,EIF4G2,TENM1,C3orf18,EMX2,EPHA5,SLC43A2,TLR7,KATNAL1,REEP2,WAC,TUBB3,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,AMOTL2,SCARA3,MEX3B,FOXG1,PCYOX1,ANKFY1,JKAMP,STAU2,GABRA3,ZNF44,GABRG1,CAB39,ZMYND11,GALC,IQGAP2,C15orf41,SEPT9,DNER,ALDH1L1,TUBGCP4,AHDC1,PPARGC1A,TOX3,GPT2,ADGRA3,ATF7,MCHR1,GPER1,CECR2,PCLO,GRIK1,NR3C1,GRM2,GRM5,LINC01089,KAT7,LINC01551,SOX21,GUCY1A1,MAP4K5,FAM222A,CELF3,RASSF8,HAS2,HPS5,GPR45,FRMD3,MIER3,HLF,SCRG1,SYNPO,AGBL5,AGFG1,SHISA6,IGF1,NIM1K,LIX1,ZNF385B,LRRTM3,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNK1,KCNN2,KIF5C,KIT,C2orf80,PIK3AP1,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,LRP1B,MEIS1,AFF1,MOBP,ZNF680,MXI1,MYCN,MYH6,PABPC1L2A,NAP1L2,NDUFA5,IDNK,NELL2,NFYA,NOS1,NOVA1,NPTX1,NPTX2,TBC1D25,OGDH,OPCML,KCNK10,PDE1A,PDE4B,PDE4D,PIRT,CYTL1,PFKFB3,SEMA5B,PIK3C2A,ZFYVE21,FAM216A,PDZRN4,STRN3,SCHIP1,ING3,FAT3,SH3KBP1,POU6F1,PKIA,HYDIN,RELN,VPS13C,DEF8,MDGA2,ZIK1,PTPRD,PTPRZ1,TMEM231,PPP2R3C,QDPR,RAB3A,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,ARID4A,RBBP6,BSDC1,GTDC1,FIGN,RFX3,RFX5,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,GLDN,PRR5L,LGR4,YJEFN3,RYR3,ZNF331,SALL1,SATB1,ATXN1,SCN4B,SCN8A,SCP2,SELL,GALNT10,HSPA4L,PUF60,ITSN1,CPEB3,DOCK10,AMBRA1,FNDC3A,R3HDM2,SLITRK3,NUBPL,RAB3GAP1,SLC12A2,CPEB4,MAST1,RCOR3,RIMS1,CABCOCO1,SNRPN,KDM4B,SCN3B,PDZD2,KIF21B,FNBP1,KDM3A,EMC1,KDM4C,PEG10,ZBTB43,TSPYL2,RBM26,LMO3,EPB41L3,LARP4,SEPT8,DIP2A,STXBP1,AJAP1,SYT11,MLC1,VAMP1,C3orf70,SYT1,SYT4,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,PDLIM2,AGTPBP1,TBCEL,TMEM136,ATMIN,TCEA1,TCF4,SIN3B,SATB2,ZEB1,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,TMEM151B,PCDHB7,ARHGEF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TGFBR3,TLR4,ZFP91,HEY2,TMOD1,RIMBP2,PARD3,RBFOX2,TPD52,RASD2,RGMB,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,BCL2L13,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,CLDND1,RICTOR,XRCC4,PCDH20,ZNF24,FMN2,SLC26A10,SPIRE1,ZNF213,SMARCAD1,EMSY,EVI5,GDPD5,LINC02210,NAV3,SNX27,FAM47E,WNK3,SLC17A6,PDSS2,FAM13C,FZD3,DOCK8,FBXO36,CASC15,FAM219B,RNF170,PIANP,NETO2,SOCS4,SLC4A10,CPNE4,JPH3" MicroRNA hsa-miR-194:mirSVR_lowEffct hsa-miR-194:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-183 6.46E-180 1.66E-181 1.53E-180 464 1926 "ACADM,CLK4,ADCY2,RNF157,ERMN,PLEKHH1,PWWP2A,BEND6,SLC44A5,AP1B1,GPR158,RTL9,OSBPL1A,TBC1D14,OSBPL6,WDR35,CC2D2A,ARHGAP20,ZFAT,USP37,AQP6,CDC14B,CASK,ARHGAP5,CAPRIN2,ASPH,CCAR2,SLC4A4,NOL4,ADAM23,BACH1,LINC00847,BBS2,MPDZ,SEC11C,CFLAR,BMP7,WASF1,MMD2,CACNA1B,LURAP1,CALM1,PTBP2,CAMK2G,TRIM41,CANX,CAST,HIP1R,CERS5,TMEM257,CDH2,CCPG1,CHM,CHN2,CASC2,JAM2,NDST3,LHX2,PLAA,KIAA1549L,CLCN4,ABCG2,NIPBL,CNGA3,CNR1,COL4A5,COL9A2,COL11A2,RTTN,MYRIP,ZNF521,HS3ST5,CHD1L,FAM171B,CLOCK,CRHBP,ANKRD44,OSBPL3,CSNK1G3,SOCS5,PHACTR3,CNTNAP2,FAM169A,DZIP3,APPL1,CTH,CFAP61,RUBCN,DOCK4,HDAC9,ARHGAP24,TOX,ZNF337,KCTD8,SCRN1,SPOCK2,DBI,GIT2,PITPNC1,DNAJC6,C8orf34,MYEF2,LYPD1,GSDME,POM121,SACS,SPOCK3,RABGAP1L,SEC16A,RAB39B,DMD,HS3ST2,SLC29A4,NR1D2,DNM2,DPYSL2,ABI1,ARRDC4,ECM2,DUSP9,MAMLD1,ATL1,RASGRP1,KLHL5,RBM12,FAM13A,PHF20L1,SUGP2,MRO,GOLGA7,ASB3,EIF4G2,TMEM35A,PAN3,VPS13B,EPB41L2,LRRC17,EPHA5,GPHN,DENND4A,NCALD,CDHR1,RRAGB,EYA1,ABCA8,SCML2,EFEMP1,ATP8A1,SEC24B,SLC9B2,FGFR1,FGFR3,TMEM164,MEX3B,SYNCRIP,C2orf88,UFM1,PDLIM5,NPTN,ST6GALNAC3,SARAF,MEGF11,DKK3,GAB1,GABRA1,GABRA2,GABRA5,GALNT15,GABRG1,DISC1,WASF3,CPLX2,PPARGC1A,GJB1,RND1,GLRB,ZNF638,KIAA1958,KDM2B,HTATSF1,GNAL,FERMT2,ADGRA3,GPD1,GPD2,GPM6B,LILRA1,STON1,EML4,PCLO,GRB10,GRIK2,GRM3,GRM7,KAT7,ZBTB45,FAM107A,MAP4K5,WIF1,MAEL,UBE2QL1,FRMD3,HLF,HMGB1,AGBL5,NEGR1,OPALIN,CELF5,SMAP1,IRF8,IGF1,LRRCC1,IL6R,DIPK1A,ITGAV,ITPKB,KCNA4,KCNJ10,KCNK1,KCNK2,KIF5C,KPNA5,STXBP5,CYP27C1,LIFR,SYTL4,SMAD1,PIK3AP1,MAP2,MBNL1,MBP,MEIS1,KITLG,CD200,ERICH3,RSPO2,MYCN,MYO7A,NCAM2,ZC3H12B,NCF2,NDUFA5,NELL2,NF1,OTOGL,NFE2L2,NOVA1,NRCAM,NTRK2,NUCB2,CHAMP1,OLR1,OPRL1,PCMT1,PCSK2,CDK18,PDE3B,ENPP2,ANLN,PIK3R1,ZNF655,RETREG1,XRN1,JAKMIP1,SMIM7,HMGCLL1,PURG,LRP12,PSAT1,EPB41L4B,NXPH1,MED1,CRLS1,PPP2R5E,RASGEF1B,RAB39A,MAPK4,EPDR1,HYDIN,DIRAS2,WBP1L,PIGG,PTCH1,MTMR10,PTK2,STK32A,ZIK1,PTPRO,C1orf109,TUG1,PPP2R3C,CEP97,PLEKHB2,ZNF793,RALGDS,SH3TC2,ATG16L1,FAT4,ZCWPW1,OXR1,RBBP6,VEPH1,BSDC1,REV3L,FIGN,UBR7,KCTD17,KLHL11,RPRD1A,ZNF532,ALG9,RORB,ELP2,CCDC102B,NEK11,ZC3H14,ACER3,LGR4,RXRA,NCBP3,ZNF331,AMER2,SEMA6D,SATB1,HOGA1,LINC00461,SMPD3,SOX6,SELL,SUPT20H,KIF27,TRA2B,SGK1,KIF21A,PPP1R9A,SH3GL2,SH3GL3,ARX,KIF16B,CHD9,FNDC3A,CNKSR2,SYBU,ST3GAL3,DZIP1,ANKRD6,FAM81A,PEX26,PPP4R3A,BTBD3,EPN2,SMTN,SLC8A1,RAB3GAP1,SLC8A3,ARHGEF40,SHANK2,SLC14A1,EFHD1,SLIT1,SMARCA4,ANKRD36,KIF13A,LMBRD1,TMCC1,TRERF1,SOX2,KIF21B,KDM3A,MYCBP2,KIF1B,CDK19,NPAS3,C11orf87,ATP10B,PBLD,LARP4,SSPO,ELOVL4,SEPT8,STXBP1,NECAB1,MLC1,FGD4,SYNE2,COBL,ANKRD28,C12orf76,TAC3,TACC1,KAZN,FBXW11,ATMIN,SATB2,ZFP90,TCF7L2,ZEB1,WDR7,PHF24,NSD1,AKNA,USP32P1,CRTC1,FRYL,PMS2CL,ZFPM2,ZMAT3,TGFBR3,ZNF106,AKTIP,TIMP4,TJP1,R3HDM1,TPD52L2,RGMB,SYNPO2,PDSS1,RUNDC3B,NEIL2,TRO,TTC3,CLHC1,CADM1,FAM155A,UBE3A,UGT8,SLAIN1,PITPNB,PLEKHH2,NSD2,SLC13A3,XPO1,SLC47A2,SF1,ZIC3,ZNF711,KCNT2,ATP6V0E2,ZNF70,ZNF138,TMEM237,ZNF195,FTSJ1,PLPPR5,ZFAND5,UPF3A,DHX33,WNK1,CA10,PMEPA1,PRDM2,PARP6,PRDM10,ADAMTS9,SCG2,HPS4,KCNAB1,FAM47E,SLC17A6,PHTF2,JMJD1C,FXR1,FRMD6,NETO1" MicroRNA hsa-miR-4295:mirSVR_lowEffct hsa-miR-4295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-183 8.68E-180 2.17E-181 2.00E-180 425 1614 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,USP31,PWWP2A,PTCHD1,KCTD16,AK2,ADGRF5,LRRC7,SPARCL1,BCAR3,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,PHF12,PPFIA2,EPB41L5,TNRC6C,SHTN1,ASCL1,ATM,ATP1A2,ATP2A2,ZNF582,MTMR9,B3GALT2,N4BP2L1,DOCK11,KSR1,BMPR1B,SGCE,NIPA1,LDLRAD4,CALB1,CAMK2D,CANX,VSTM2A,USP2,SEPT7,REPS2,CDC42,MAGI1,NOG,SRSF11,MS4A7,EPS15L1,COG1,FBXO7,C4orf33,QKI,HECTD1,MAP4K4,RAB26,FHL5,CNR1,IQCK,SLC25A27,AKAP5,SLC4A7,SLC4A8,TBPL1,AHCTF1,ZNF521,CREB5,HAPLN1,FEZ2,MICAL2,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,MAML1,DGKG,TMEM170A,DAPK1,CTIF,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,MAGI2,KLHL3,SNAP91,SV2B,NTM,G3BP2,FAM107B,DLG2,GRIN3A,RAB39B,NYAP1,USP3,DNAH9,MED12,DNM2,CPEB2,SLC25A18,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,HEYL,TMTC1,FRY,EIF4G2,TENM1,C3orf18,EMX2,EPHA5,RABEPK,SLC43A2,NCALD,CEP85L,TLR7,EXTL2,KATNAL1,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,SCARA3,MEX3B,FOXG1,PCYOX1,ANKFY1,PSD2,JKAMP,TACC2,STAU2,MSANTD4,GABRA3,ZNF44,CAB39,ZMYND11,GALC,ZNF274,IQGAP2,DNER,TUBGCP4,PPARGC1A,DBF4,TOX3,FERMT2,GPT2,ADGRA3,ATF7,GPR12,MCHR1,GPER1,CECR2,PCLO,GRIA2,GRIA4,GRIK1,NR3C1,GRM2,LINC01089,KAT7,LINC01551,SOX21,GUCY1A1,MAP4K5,FAM222A,CELF3,HAS2,HPS5,FRMD3,MIER3,HLF,SCRG1,TLX1,AGFG1,IGF1,NIM1K,LIX1,IL11RA,ZNF385B,LRRTM3,NME9,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNJ16,KCNK1,KCNN2,KIF5C,KIT,IPO5,C2orf80,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,MEIS1,AFF1,WDR49,ZNF680,ADAM22,SCG3,MYH6,MYO9A,PABPC1L2A,NAP1L2,NDUFA5,IDNK,NOVA1,NPTX1,NPTX2,HCN1,NUMA1,TBC1D25,OGDH,OPCML,KCNK10,PDE1A,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,FAM216A,PDZRN4,STRN3,RC3H2,ING3,FAT3,POU6F1,TATDN3,PKIA,HYDIN,RELN,VPS13C,DEF8,MDGA2,ZIK1,PTPRD,PTPRE,PTPRO,TMEM231,PPP2R3C,QDPR,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,ARID4A,RBBP6,BSDC1,GTDC1,RFX3,RFX5,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,GLDN,PRR5L,LGR4,YJEFN3,RYR3,ZNF331,SATB1,SCN4B,SCN8A,FNIP1,SELL,HSPA4L,PUF60,ITSN1,CPEB3,DOCK10,AMBRA1,FNDC3A,R3HDM2,NUBPL,RAB3GAP1,SLC12A2,CPEB4,MAST1,RCOR3,RIMS1,CABCOCO1,SNRPN,SON,KIF21B,FNBP1,KDM3A,EMC1,TSPYL2,RBM26,EPB41L3,LARP4,SEPT8,RGL1,DIP2A,STXBP1,AJAP1,MLC1,FGD4,VAMP1,C3orf70,SYT1,ANKRD28,SYT4,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,FAM208A,PDLIM2,AGTPBP1,TBCEL,TMEM136,ATMIN,TCEA1,TCF4,SIN3B,SATB2,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,TMEM151B,PCDHB7,ARHGEF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HEY2,TMOD1,DAAM2,RIMBP2,TNFRSF1B,PARD3,RBFOX2,NPL,NR2C2,SMUG1,STXBP4,TRPS1,HIRA,RPL7L1,UBE3A,LINC00689,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,CLDND1,XRCC4,PCDH20,FMN2,SLC26A10,LYPD6,TCEAL7,SPIRE1,SMARCAD1,CSDE1,EVI5,LINC02210,PRDM10,PCDH15,NAV3,SNX27,KCNAB1,FIP1L1,FAM47E,SLC17A6,PDSS2,FAM13C,DOCK8,RTN4,PHTF2,FBXO36,CASC15,FAM219B,RNF170,PIANP,NETO2,SOCS4,SLC4A10,JPH3" MicroRNA hsa-miR-654-3p:mirSVR_lowEffct hsa-miR-654-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-183 1.74E-179 4.25E-181 3.91E-180 459 1889 "RALGAPA1,CLK4,NBAT1,ACTN1,NDRG3,TMEM132B,DSCAML1,SLC12A5,SORCS1,PLEKHH1,ESYT2,ADRA1D,SLC24A4,INTS2,NME5,WDR35,OSBPL8,AK2,ZNF578,ADGRF5,CARNS1,PCDH10,BEGAIN,ZFAT,DPP10,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,DDO,PHYHD1,SHTN1,CDC14B,ARNTL,NCOA1,NUMB,RASL11B,ATM,STX16,ATP2A2,SLC2A11,CADM3,ATP6V0A1,BACH1,SNAI3-AS1,SCAPER,SGCE,MMD2,BTRC,CACNA2D1,CALB2,CALM1,VXN,PRC1,KYAT1,USP6,INA,LRBA,CDH8,LRRFIP1,MAGI1,DLGAP1,CCPG1,CACNA2D2,SRSF11,CHGB,NDST3,NRXN3,NRXN2,CLTA,TJP2,LY86,CNTFR,AKAP6,SUMF2,LETMD1,MAGED1,TBPL1,SMARCAL1,MYRIP,MFSD4A,PREPL,HAPLN1,ANKRD44,GDA,SNCAIP,SEC24C,OSBPL3,VAC14-AS1,PHACTR3,SLITRK5,KIAA0040,PLCXD3,NRSN1,ECE2,BOC,DOCK4,FGFR1OP2,SNPH,FRMPD4,TOX,EARS2,TBC1D5,MATR3,DGKB,TMEM170A,DAPK1,TOMM20,SCRN1,CTIF,SPATA2,PLEKHM1,MYEF2,GSDME,SPOCK3,CD99L2,DOCK2,GNE,ECM2,FARSB,ABCC9,GOLT1B,AASDH,WDPCP,EDN3,EDNRB,PHC2,FCF1,SYT15,SEMA3D,TMTC1,CELSR3,PHF20L1,SUGP2,MBNL2,RASA4,AASS,GOLGA7,COPS4,PLEKHA1,ELAVL3,CERCAM,CALCRL,EPHA5,EPHB1,DENND4A,EFS,DNAJC27,RASL12,EXTL1,FAM198B,TMEM132C,EFEMP1,DLC1,CHST15,ZSCAN30,ZNF589,GORAB,KIAA1109,OLFM1,FGF12,FGF14,AMOTL2,POLK,MEX3B,HPCAL4,SYNCRIP,FOXO3,EVL,ANKFY1,PSD2,COQ5,WDR83,STAU2,B3GAT1,ZNF512,PHYHIPL,MEGF11,SALL3,NEK6,NCKAP1,IQGAP2,CPLX2,KIAA1841,ARFIP1,CYP46A1,GHR,GK,COPS8,SPIN1,LUZP2,ATF7,GPR12,CCDC184,EML4,TMEM121B,RAPGEF1,GRIA4,GRIK1,NR3C1,ATE1,LINC01551,PSIP1,ATOH8,GYG1,RASSF8,HAS2,NXPH2,ZNF491,OPALIN,LINC00667,DOCK7,KIAA1755,IGSF1,LIX1,BRINP3,INSM1,SLC35G1,KCND2,KCNJ3,KIF2A,KIF5A,A1BG-AS1,STXBP5,L1CAM,HECTD2,NCOA7,GPR155,ZFYVE27,MARK1,LYPLAL1,SYT9,LDLRAD3,MDM4,LRP1B,MEIS1,MEIS2,PPM1L,MMP16,GIT1,COL28A1,DBNL,SAMD5,SESN3,CCDC80,MT3,THYN1,LAYN,MYO6,MYO7A,ZNF862,PABPC1L2A,P2RY13,NF1,SLCO1C1,DNHD1,SLC11A2,HCN1,NTRK2,NTRK3,GPR88,CHAMP1,OPCML,OPHN1,CLDN11,P2RX7,GPR137C,SNTG1,PCSK2,PFKFB2,TMIE,CCSER2,SNX10,FTO,HMGCLL1,PURG,ANKRD16,SCHIP1,PRRX1,FAT3,NXPH1,DRAM2,MED1,PPM1B,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,RAB39A,MAPK3,MAPK10,MASP1,SAMD9,SYTL2,GON4L,GDPD2,MDGA2,CNTLN,UHRF1BP1,MTMR10,PTN,TMEM260,ZIK1,PTPRB,PTPRD,C1orf109,TUG1,TMEM231,MARCH1,RAD51D,FAM66C,RASGRF2,ZDHHC14,BSDC1,RDX,ZMAT4,REV3L,GTDC1,RFX4,RGS3,RGS12,RNF220,SLC25A36,NUDT11,RPRD1A,RNH1,DCUN1D2,CARF,CCDC102B,SPIN3,STK32B,FAM161B,CLIP1,RYR3,NCBP3,ZNF331,FAM192A,SBF1,CSRNP3,ATXN7,SLC30A10,ZFP2,PEAR1,MRAS,SCAF8,ITSN1,PPP1R9A,R3HDM2,NLGN1,SEC31A,ZNF365,SLC2A5,RUFY2,PKNOX2,SLC8A2,SLC8A1,RAB3GAP1,TMEM132D,ELMO2,EPC1,COA1,SMARCC2,CDK5RAP2,RCOR3,LIMCH1,RIMS1,SNRPN,FAM126B,SON,SOX5,KDM3A,PEG10,SPTB,TSPYL2,RBM26,NFASC,C11orf87,ZNF302,SS18,SEPT8,TTBK2,SULF2,ARHGEF9,NUDT10,PLCB1,SYT1,SYT4,C12orf76,TAC1,TACR1,CAMTA1,TAF6,MLST8,IQCE,ANO4,ACSL6,SYNE1,DOCK9,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,CRB1,AKTIP,TIAM1,BHLHB9,NPL,C9orf85,RGMB,NR2C2,TRO,TRPS1,DCBLD1,TUB,UBE3A,PLEKHH2,MTCH1,PLPPR2,GUSBP1,XRCC4,CFAP298,SF1,ZIC1,MICU3,ELFN1,FMN2,LYPD6,ZNF138,ZBTB16,REEP1,ANKS1B,WNK1,PMEPA1,PRDM2,PRTFDC1,DNALI1,LRP8,STOX2,RNF103,URM1,CAB39L,FAM47E,PDSS2,GOPC,DOCK8,HNRNPA3,JMJD1C,RNF170,VANGL2,KLHDC1,FRMD6" MicroRNA hsa-miR-3074:mirSVR_lowEffct hsa-miR-3074:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-182 1.11E-178 2.64E-180 2.43E-179 459 1897 "KCNH8,NBAT1,SYS1,ACTN1,XKR4,ADCY2,CCDC85A,SORCS1,SNX30,PTCHD1,INTS2,PCDH19,TBC1D14,WDR35,CC2D2A,SMIM17,ALCAM,FAM135A,GPRASP2,AMPD2,OGT,DPP10,EP400,C6orf89,CCDC146,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APC,EPB41L5,UPRT,ALS2,DDO,USP37,PPP4R4,ZFYVE28,ATP2B1,DOCK11,BBS2,KSR1,DST,NAE1,WASF1,CACNA1B,CACNB2,CACNB4,CAMK2D,VXN,VSTM2A,CAST,ISPD,SPAG9,RUNX1T1,PRC1,LDB2,USP6,CDC42,LRRFIP1,COPB2,CASC2,SYNPR,NDST3,RAB28,NRXN3,CLCN3,TPP1,CLTA,ABCG2,CNN3,CNTN1,AKAP7,ARMC8,COL4A5,COL9A3,AKAP5,SLC4A8,MYRIP,ZNF521,CNRIP1,SLC35F1,GDA,SNCAIP,LRIG1,OSBPL3,PDE4DIP,PLXNA4,GREB1,CFAP61,NRSN1,RIMS2,ZSCAN23,RUBCN,CCDC144A,KIAA0408,BOC,DOCK4,GPRASP1,MYADM,TOX,MATR3,KIAA0586,KCTD8,DAPK1,DCC,PITPNC1,DCT,TIAM2,HP1BP3,MAGI2,KLHL3,ZC3H11A,DDX46,PLPPR4,SNAP91,SV2B,SRGAP3,WDR20,KBTBD11,CPEB2,PDCD6IP,ABCC9,GOLT1B,EBF1,EDNRA,SEMA3D,KLHL5,CELSR3,PHF20L1,ABI2,AASS,TMEM35A,PAN3,VPS13B,EPB41,EPB41L2,DMTN,EPHA5,EPHB1,RABEPK,ETV1,RCSD1,RRAGB,SIRPB1,KATNAL1,EYA1,NSRP1,FAM198B,RPS6KC1,ZSCAN30,SEC24B,KIAA1109,FGF13,POLK,MEX3B,SYNCRIP,RGPD5,FOXM1,FLT1,EFCAB2,NBEA,SPECC1,UFM1,FAM49B,TPK1,CAMKK2,CELF1,NSG1,GAB1,HRASLS5,GABRG2,TRAF3IP2,CAB39,HBS1L,ZMYND11,GALC,NCKAP1,ZNF559,DISC1,DNER,GATM,IGSF5,NFU1,GGT5,LYVE1,GK,GLS,GLUL,PCDH11X,HTATSF1,RAB40B,FERMT2,WDFY3-AS2,LILRB4,GPD2,PCLO,RAPGEF4,GRID1,GRIN1,GRM1,GRM7,GSTM5,BVES,FAM107A,GUCY1B1,MUM1,HAS2,MIER3,HMGB1,AGBL5,HNF4G,AGFG1,HTR2A,HTR5A,FAAP20,ZNF546,IGF1,IGFBP1,TJAP1,SCIN,INSM1,ITGAM,KCNA1,KCNJ3,KCNK2,KIF5A,KLRC2,IPO5,STXBP5,KTN1,PAXBP1,HECTD2,NCOA7,SMAD1,PIK3AP1,MATN2,MEIS1,KCTD6,KITLG,PPM1L,AFF1,MMP16,MN1,ERICH3,MRPL42,SESN3,CCDC80,PTOV1,MTTP,MYCN,NCAM2,NDUFA5,NEUROD1,SLCO1C1,NFIA,NOVA1,DNHD1,NPR2,SMIM11A,NTRK2,OCRL,GPR88,CHAMP1,OMG,GPR137C,GLIPR1L2,PAK3,PCDH9,PDE3A,PDE3B,PDGFRA,ENPP2,GPR85,BEST3,NLGN3,SERPINI1,NALCN,PIK3R1,ZNF655,SNX10,RETREG1,TMEM38A,FAM216A,PLCL1,PDZRN4,MAPKAP1,RC3H2,MAGEL2,DRAM2,MINDY2,CRLS1,PRKCB,PRKCZ,GRAMD1C,DCHS2,LRRC49,CNTLN,PLPPR1,ZSCAN32,PTPRG,PTPRZ1,PPP2R3C,FAM184A,RAP1GDS1,ENOX1,OXR1,KHDRBS2,ZYG11B,GTDC1,RFX5,NUDT11,PBRM1,RNASEL,CCDC82,SETD5,ALG9,KIRREL1,RORB,PCMTD2,RPE,MCMBP,ATP8B4,TCP11L1,STK32B,LGR4,ABCA11P,CCDC112,FOXRED2,SEMA6D,ATXN2,LRRTM4,FAM19A1,FNIP1,SEC14L1,SOX6,SCAF8,SGK1,KIF21A,ITSN1,ARX,SHC4,FNDC3A,CNKSR2,NLGN1,ANKRD6,WDR37,PREX2,EPN2,SLC6A1,KANSL3,RAB3GAP1,CCDC88A,SLC12A2,SLC14A1,SLCO1A2,SLC22A4,SLIT1,SORCS3,MYH15,ANKRD36,LIMCH1,SNAP25,SNCA,MBD5,SNRPN,MYO16,USP33,SCN3B,DOP1A,PDZD2,SOX2,BDP1,FNBP1,SOX11,HECW1,UHRF1BP1L,MYCBP2,C11orf87,TAB2,ITPRID2,SS18,NXT2,SEPT8,RGL1,ADHFE1,KANK1,KLHL7,SYNE2,VPS13A,SYN2,ANKRD28,ATP11A,ANKRD12,FAM208A,ADGRL3,AGTPBP1,FBXW11,ANO4,VWA3A,DMXL2,CLASP1,RALYL,PCDHB4,ARHGEF12,PUM2,USP32P1,SIK3,FAM200B,PMS2CL,CRB1,HHIP,ARL10,TLL2,BEX4,CSMD1,TPM1,RGMB,SYNPO2,METTL3,SMUG1,RUNDC3B,TRPS1,TTC3,CADM1,UBE3A,AMOT,UGT8,PITPNB,FLRT2,VLDLR,NSD2,WRN,GUSBP1,ZIC1,MICU3,KCNT2,ZBTB38,REEP1,POLR3H,PLPPR5,SMARCAD1,DHX33,WNK1,EMSY,SLC38A1,EVI5,TMEM178A,HPS4,FIP1L1,FAM47E,WNK3,PDSS2,EPM2A,FAM13C,FZD3,DOCK8,RTN4,FRMD6,NETO2,SLC4A10" MicroRNA hsa-miR-129-5p:mirSVR_highEffct hsa-miR-129-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.65E-182 5.42E-178 1.26E-179 1.16E-178 441 1757 "AS3MT,NCKAP5,ACTN1,FAM43B,XKR4,SLC25A25,CSMD3,NDRG3,KLHL32,ADD1,ADD2,ADD3,ERMN,PWWP2A,PTCHD1,ZNF608,PCDH19,WDR35,AK2,TAOK1,ADGRF5,SEMA6A,SPOP,ABCD2,AMPH,CDC42BPA,ANK2,ANK3,CCDC146,PHF12,PPFIA1,APC,ALS2,LRRC4C,MIER1,TMEFF1,ARNTL,MARCH3,ASPH,ZBTB10,NCOA1,EIF4G3,ATP2B2,ATP2B3,RNF182,CADM3,NOL4,ADAM23,TTLL9,BACH1,ADGRB3,SEC11C,BCHE,CACNA1B,CACNB2,CACNB4,CALM1,CAMK2D,VXN,MAP7,RUNX1T1,CBFA2T2,TMEM257,CDH8,LRRFIP1,CDH18,LGI1,MAGI1,DLGAP2,TIGD7,NOG,LHX2,KMT2C,NRXN1,NRXN2,COG1,DGCR9,CLTA,DNAJB5,QKI,LY86,NIPBL,CNN3,CNR1,ARMC8,SLC25A27,SMARCAL1,NRG2,CHD1L,ZNF385A,SEC31B,PREPL,CREM,CREB5,GDA,TRIM69,LRIG1,CSNK1E,SIPA1L1,VCAN,CNTNAP2,KIAA0040,PHF14,RIMS2,USP6NL,NOS1AP,HDAC9,GPRASP1,GAPVD1,TCAF1,ARHGAP24,FRMPD4,TOX,ZFYVE16,KIF26A,LIN54,MATR3,KCTD8,PABPC5,ZEB2,MYEF2,TIAM2,CEP170,ZC3H11A,DDX46,PLPPR4,SPOCK3,NTM,AK5,USP3,NR1D2,SLC25A18,ABI1,PDCD6IP,DTNA,DNAJB6,ABCC5,ABCC9,GOLT1B,EBF1,EDN1,FAM135B,ANKRD46,CNNM1,KLHL5,FSD1L,RBM12,EGR3,AASS,ELAVL4,DCTN4,OLIG2,VPS13B,EPHB1,KCNMB2,GPHN,SRRM1,CEP85L,ETV1,NRN1,F3,CLVS1,FAM198B,CACNG2,TMEM132C,ACSL4,TAOK3,DLC1,GORAB,MED12L,KIAA1109,FGF12,FGFR1,AMOTL2,PRKAG2,FHL1,CAP2,SYNCRIP,JKAMP,KHDRBS3,CELF1,CSPG5,MEGF11,DKK3,HRASLS5,GABRA3,CAB39,HBS1L,JPH4,ERAP1,ZNF559,C15orf41,DISC1,MSTN,GFRA2,PCDH17,GHR,GK,GLYR1,GLS,TNRC6A,PCDH11X,ZNF638,CBX1,KDM2B,GNAO1,FERMT2,TDRKH,LPAR4,GPR37,TMEM121B,PCLO,RAPGEF4,PLCD4,GRIK2,SERP2,GRM3,GRM5,GRM7,GRM8,LINC01089,GSN,RNF165,WIF1,FRMD3,KLF12,BACH2,MIER3,HMGB1,HNF4G,HNRNPK,IRF8,FAM95B1,RBPJ,DOCK7,USP54,KCNB1,KCNJ3,KCNK1,KIF5C,STXBP5,CYP27C1,SYTL4,HECTD2,FGFBP3,MAP2,MATN2,MBNL1,EFHB,TM6SF1,LRP1B,MEIS1,MEIS2,MMP16,MOBP,COL28A1,SESN3,MYO9A,MYT1,NAP1L1,NDP,NELL1,NEUROD2,NFE2L2,SLC11A2,NRCAM,SMIM11A,HCN1,NTRK2,OCRL,OXTR,PAK3,PAX6,PCDH9,PCSK5,PCSK2,PDE1A,BEST3,ABCB1,NALCN,ZNF655,CCSER2,RETREG1,PLCL1,SLC25A23,MTRF1L,C11orf49,PDZRN4,LRP12,ING3,EPB41L4B,FAT3,SH3KBP1,MINDY2,LRRN3,PPP2R5E,PPP3CA,PRKCB,MASP1,SAMD9,SIDT1,CNTLN,PXK,PTN,TMEM260,PTPN13,PTPRZ1,USP47,RAD17,ZNF793,RALGDS,NWD1,OXR1,ARID4A,RET,ERI2,FIGN,RGS7,ARHGEF10L,SLC25A36,RIC8B,RPRD1A,RORB,NEK11,FBXW7,ATP8B4,ACER3,MAP6D1,KCNIP3,TRAPPC13,ATXN7,SCN8A,SCP2,ASIC4,IL17RB,SEC14L1,ITSN1,MAGI3,NLGN1,RPH3A,SEPHS1,RAB3GAP1,SLC8A3,CCDC88A,BTBD7,ATF7IP,SLC22A4,TET1,SMARCE1,LIMCH1,SNCA,MBD5,SNRPN,UNC80,MYT1L,SOX2,SOX3,SP2,SP4,NMNAT2,ENKUR,MYCBP2,KDM4C,ATP10B,POGZ,SAMSN1,SSTR2,ZC4H2,NKAIN2,ERBIN,NXT2,TTBK2,ADHFE1,KLHL7,FGD4,VAMP1,NUDT10,FNDC9,SYT1,CAMTA1,TAL1,CAMSAP2,UNC5D,ADGRL3,TCF4,RPGRIP1L,WDR7,SYNE1,PCDHB3,FRYL,ZFPM2,CRB1,GPR161,ARL10,BHLHB9,ERCC6L2,LRRC8A,KAT6B,TP53BP2,CHST5,SYNPO2,TRIO,TRO,FNDC5,SGK3,CADM1,RPL7L1,FAM155A,SLAIN1,PITPNB,TBC1D15,RBFOX3,XPO1,XRCC4,ZIC2,TRIM9,FMN2,ZNF74,PLPP4,CELF4,REEP1,FSTL5,ANKS1B,SPIRE1,SYNC,UPF3A,PMEPA1,ZXDA,EMSY,STOX2,SCG2,PCDH15,KCNAB1,WIPF2,SLC17A6,EPM2A,DNAH10,PAK5,TRAM2-AS1,GAN,JPH3" MicroRNA hsa-miR-30a:mirSVR_highEffct hsa-miR-30a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.75E-181 9.80E-178 2.23E-179 2.05E-178 453 1857 "RALGAPA1,CLK4,ABHD6,ARID1A,CSMD3,GALNT16,GALNT13,RNF157,ADD1,BRAP,CDC7,SORCS1,ERMN,KIAA1211,LRFN2,ADRB2,AP2A1,AP1B1,ZNF608,INTS2,KCTD16,RTL9,HACE1,TAOK1,SMIM17,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,APC,UPRT,ALS2,CACHD1,VAT1L,USP37,PPP4R4,TMEM263,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B1,ATP2B2,DPY19L3,ADGRB3,SEC11C,BCL2L2,NRP2,BID,KSR1,DST,MTMR2,BSN,CACNB2,CALB2,CABP7,CAMK2D,SLC25A14,CARS,CBS,SLC5A11,USP2,SYNGR3,DGKI,SEPT7,ZBED1,LGI1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,NDST3,KMT2C,NRXN3,FAM189A2,QKI,MAP4K4,NIPBL,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,ZFP28,SLC35F1,PNKD,CLOCK,SLC32A1,GDA,OSBPL3,CSNK1G3,GREB1,CTNND2,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TOX,PHF19,TBC1D5,MATR3,KCTD8,MAML1,TOMM20,YTHDC1,JAKMIP2,C8orf34,CEP170,MAGI2,BLOC1S6,ALKBH8,PLPPR4,SACS,SPOCK3,RABGAP1L,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,DMTF1,SLC12A6,PDCD6IP,DTNB,MAMLD1,DYRK1A,DNM1L,ABCC9,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,EML1,DCTN4,EN2,EPB41,EPB41L2,LRRC17,KCNMB2,STX2,DENND4A,CDHR1,RCSD1,EXTL2,ABCA8,FABP7,SH3YL1,SCML2,ATP8A1,GORAB,POLR1B,AMOTL2,PRKAG2,SCARA3,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,SORBS1,UFM1,FAM49B,ATP6V1H,KHDRBS3,DACH2,NSG1,MSANTD4,NRG3,OGA,ZMAT1,STAG2,GABRA5,CHL1,GABRB1,TRAF3IP2,HBS1L,JPH4,GALR1,IP6K3,ERAP1,ATP8A2,KIAA1841,MYOZ2,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLRB,GLS,TNRC6A,GNAO1,GNAS,ADGRA3,PRUNE2,GPM6A,TDRKH,GPR19,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,GRM1,GRM3,GRM5,CIT,FAM19A2,GUCY1B1,CELF3,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,SMAP1,RAB41,C2orf72,SOWAHA,DOCK7,ZNF678,DIPK1A,LRRTM3,LRRTM1,JAK1,KCNA2,KCNJ3,STXBP5,LAMP2,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,SYT9,CHIC1,MEIS2,MID1,PPM1L,ERICH3,MRPL42,JAKMIP3,ADAM22,PABPC1L2A,NAP1L2,NAP1L3,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,OMG,ZNF827,PCDH9,PDE4D,PIRT,PIK3CD,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,SLC22A23,LAMA1,ANKHD1,ELOVL2,PXK,TMEM260,PTPN13,PPP2R3C,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,ERI2,FIGN,RGS7,TTLL7,RNF220,RPRD1A,SETD5,EXD2,RAVER2,CARF,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,LINC00461,SLC30A10,SUPT20H,SCG5,ITSN1,FRMPD1,ARX,KIF16B,CPEB3,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,PAAF1,ZNF365,FAM81A,KANSL3,PKNOX2,SLC6A9,SPHKAP,TET1,ZFP1,SORCS3,SMARCE1,RCOR3,TTC17,LIMCH1,SNRPN,TMCC1,MYO16,SON,BDP1,DOK5,KDM3A,SP4,HECW1,BEX1,KIF1B,RBM26,NPAS3,SPART,CLASP2,SSTR1,SSTR2,NKAIN2,STAU1,ZSCAN29,NEK4,RGL1,STXBP1,SYPL1,COBL,SYT4,DDHD2,CAMTA1,MCF2L,ADGRL3,ANO4,DMXL2,SATB2,USP22,CLASP1,WDR7,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,CRB1,SLC44A1,GZF1,ACTR6,TLL2,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,ZMYND8,DCBLD1,ANKRD20A2,SSBP2,RFTN2,TMEFF2,PITPNB,CCDC14,MICAL1,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,CA10,SLC30A4,MAP3K12,CSDE1,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,PAK5,HNRNPA3,PHTF2,CERS6,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-454:mirSVR_highEffct hsa-miR-454:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.31E-180 5.23E-176 1.16E-177 1.07E-176 415 1570 "RALGAPA1,SDE2,CLK4,NCKAP5,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,BEND6,GPR158,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,ADGRF5,ALCAM,SRPX,ABCD2,FAM135A,MRTFA,LRCH2,LCORL,USP28,APAF1,APBB1,APC,API5,AQP4,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,STX16,ATP2B1,ZNF583,N4BP2L1,NOL4,DPY19L3,ADAM23,TTLL9,ADGRB3,NRP2,DST,C5,CABP7,THSD7A,KALRN,CAMK2A,SYT6,CAST,MAP7,RUNX1T1,USP6,SEPT7,TIGD7,CFL2,SYNPR,KMT2C,ZFYVE9,PLAA,KIAA1549L,CLTC,TJP2,SRP14-AS1,NIPBL,CNR1,AKAP7,ARMC8,FAM149A,AKAP6,BTF3L4,ACBD5,HS3ST5,CLOCK,CREM,GDA,CSF1,RGS6,LRIG1,SIPA1L1,CHD5,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,GREB1,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,HDAC9,FGFR1OP2,DCAF8,ZFYVE16,LONRF1,DAPK1,SPATA2,YTHDC1,ELMSAN1,ZEB2,FBXL5,KIAA0319,CEP170,RHOBTB1,SPOCK3,WDR20,RAB39B,DPYSL2,ABCC5,ABCC9,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,RBM12,FAM13A,KMT5B,EGR3,ASB3,CERCAM,PAN3,DCTN4,ENPP6,RABEPK,SRRM1,CEP85L,RASL12,F3,WAC,ACSL4,TESK2,GORAB,FER,MED12L,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,PSD2,SGIP1,NELFCD,NBEA,TPK1,NPTN,ATP2C1,NRG3,FYB1,MEGF10,GABRA1,GABRB3,HBS1L,B4GALNT1,GAP43,ERAP1,DNER,MYOZ2,ARFIP1,SESN1,ADAM28,RAB30,GLRB,GLS,TNRC6A,MSL3,KDM2B,MAP7D2,INSM2,RAB40B,FERMT2,PRUNE2,GPM6A,GPR34,RAPGEF4,GRB10,PLCD4,GRM5,GRM7,CIT,LINC00839,RNF165,BACH2,HNMT,IRF8,ZIC5,LRRCC1,USP54,IL11RA,ZNF678,JAK1,KCNN3,CREG2,IPO5,LIG4,LIMS1,ARHGAP12,MAP4,MARK1,MATN3,MBNL1,MDM4,LRP1B,MEIS1,MEIS2,MOG,ERICH3,BCO1,MTR,LYRM9,ZNF862,MYT1,NAP1L3,NELL2,NEUROD1,NFIA,CNOT4,DNHD1,OCRL,GPR88,OMG,OPA1,OPHN1,LOC100128398,GPR137C,PBX1,PCDH9,PCSK5,PDE1C,PDE3B,PDGFRA,GPR85,PENK,PFKFB2,CDK14,CCSER2,ST8SIA5,JAKMIP1,HMGCLL1,PURG,LRP12,SCHIP1,FAT3,POU3F2,CRLS1,PPP3CA,PSD,PLPPR1,MTMR10,PTHLH,PTPRG,RAB5B,PID1,CEP97,RAD17,ATG16L1,ARID4A,RBBP8,KHDRBS2,ZDHHC14,GAL3ST4,RET,ERI2,SEC61A2,SLC25A36,RPRD1A,CCDC82,ZNF532,SETD5,KLHDC8A,CARF,GSTCD,ROBO2,EPHA10,ATP8B4,LRRK2,CNTNAP3,CLIP1,RTN1,CCDC112,LRFN5,SCN3A,FAM19A1,PEAR1,SOX6,ARX,KIF16B,CHD9,SLITRK3,SYBU,SEC31A,BTBD3,WDR47,RUFY2,YPEL4,SEPHS1,SLC8A1,RAB3GAP1,CCDC88A,SHANK2,SLC14A1,BTBD7,NAXD,ZNF667,SNAP25,SNCA,KIF13A,USP33,MYT1L,TRERF1,SOX5,BDP1,DOK5,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,ITPRID2,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,FGD4,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,CAMSAP2,FBXW11,WSCD1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,TGFBR3,SLC44A1,BHLHB9,ERCC6L2,TMOD1,TNFRSF1B,R3HDM1,CSMD1,TNS1,SMUG1,STXBP4,TRPC3,TSC1,ANO5,UBC,RPL7L1,FAM155A,AMOT,UGT8,SLAIN1,CCDC14,WRN,CFAP298,ZNF711,FMN2,ZNF74,SPHK2,TCEAL7,ZBTB38,REEP1,FSTL5,SMARCAD1,WNK1,PMEPA1,MAP3K12,MFF,PRDM2,LRP8,STOX2,PCDH15,KCNAB1,CAB39L,WNK3,PLSCR4,C12orf4,RGS7BP,MARCH8,UBE3B,PHTF2,NHSL1,SLC39A12,FXR1,FRMD6,SENP7" MicroRNA hsa-miR-1208:mirSVR_lowEffct hsa-miR-1208:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-178 7.85E-175 1.71E-176 1.57E-175 459 1936 "NBAT1,TMEM132B,ADD1,USP31,KIAA1211,ADORA3,DPY19L2P4,AP1B1,HECW2,RTL9,OSBPL8,CC2D2A,TAOK1,LRRC7,AMPD2,C6orf89,MYH7B,PPFIA4,EPB41L5,GPAM,DGKD,CACHD1,API5,CDK13,DACT3,NCOA1,NUMB,ATP1B3,ATP2A2,ATP2B1,MTMR9,RIPK1,DOCK11,TTLL9,BACH1,ADGRB3,BCL2L2,BID,SYNJ1,NIPA1,OSGIN2,WASF1,PTBP2,CAMK2D,CAMK2G,SLC25A14,SYT6,SPAG9,RUNX1T1,PRC1,CBR1,ZNF501,CLDN10,USP2,AIFM1,CBFA2T2,SCARB1,TMEM257,NEURL1,C1orf52,DGKI,CDC42,DCLK1,CCPG1,CLGN,CACNA2D2,FOXN3,CHM,RAB33A,CLCN4,FAM19A5,QKI,FHL5,AKAP7,FAM149A,RCHY1,MYRIP,ZFP28,RBM39,HAPLN1,HINFP,GDA,TRIM69,CS,LRIG1,FEZ2,ARHGEF10,IPCEF1,PDE4DIP,PLXNA4,PLCXD3,CTNND2,RIMS2,KIAA0408,GAPVD1,FRMPD4,HDAC4,KIAA0513,EARS2,KCTD8,DGKB,TMEM170A,TOMM20,PABPC5,GIT2,ELMSAN1,LYPD1,DDX46,GUCD1,SV2B,NTM,RABGAP1L,CHRDL1,GRIN3A,DMD,DOCK2,DMTF1,DSCAM,ARRDC4,ECM2,DUSP9,ANKRD46,SEMA3D,YAF2,MRO,KMT5B,ABI2,AASS,EIF5,ELAVL2,DMTN,STX2,SRRM1,EPS8,IGSF6,VPS26C,ANKMY1,ZNF585B,RPS6KC1,ATP8A1,FCGRT,STRADA,SLC9B2,GTF2IRD2,KIAA1109,FGF1,MEX3B,CAP2,PCYOX1,SYNCRIP,RGPD5,SLC37A3,NELFCD,SMC2,UFM1,ATP6V1H,ATP2C1,ZNF605,B3GAT1,DOT1L,NRG3,ZMAT1,STAG2,MEGF10,GABBR1,AHCYL1,JPH4,GALR1,SALL3,IP6K3,MTHFD2,DISC1,INPP5K,GART,CPLX2,KIAA1841,TUBGCP4,TUBA8,MSTN,WASHC2A,NFU1,PCDH17,GGT7,CRCP,RAB30,GLRB,MSL3,ZNF638,KDM2B,KCNMB4,TDRKH,GRB10,GRIK2,GRM3,GRM7,COQ10A,TMEM25,KAT7,PSIP1,FAM107A,RNFT2,ATG4C,MIER3,ELOVL5,AGBL5,C9orf129,DHX35,IRF8,ZNF546,C5orf24,DISP2,HES5,BRINP3,ZNF678,INPP1,ITPKB,METTL21A,OLFM3,KCNA4,KCNC2,KCNJ10,KCNK2,KCNMA1,CREG2,KIF2A,A1BG-AS1,STXBP5,INSYN2,LIMS1,HECTD2,ARHGAP12,C2orf80,ZNF667-AS1,MAN2A2,MBNL1,SYT9,EFHB,MDM4,LRP1B,MEF2C,MEST,KCTD6,PPM1L,AFDN,MMP16,DBNL,CTNNA3,MXI1,NAP1L2,FXYD6,ZC3H12B,NOVA1,NTRK2,OCRL,OLR1,OPA1,P2RX7,GLIPR1L2,PAK3,CNTN3,DPY19L2P2,PCSK5,PDE3A,PDE1B,PDGFRA,GPR85,PFKFB2,PFKFB4,NLGN3,GDAP1L1,TMIE,PIK3R1,SNX10,PLP1,ANKRD16,TRHDE,SLC36A4,POU6F1,LRRN3,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKN2,MAPK4,GRAMD1C,BCAS3,APTX,DEF8,GON4L,PSMD13,ANKHD1,MTMR10,SPDL1,PTPRB,PTPRE,PTPRG,PTPRO,FAM120C,PID1,PLEKHB2,ZNF793,ZCWPW1,OXR1,ARID4A,DPF2,RET,GTDC1,RGS12,RIT2,RLBP1,SEC61A2,RNF220,SLC25A36,NUDT11,RPRD1A,ZFHX4,C12orf49,RAVER2,NEK11,ARMH4,UEVLD,FBXW7,KIAA0895L,LRRK2,LGR4,SYNDIG1,SALL1,SARS,ATXN1,PRCD,SCP2,FNIP1,GALNT10,MRAS,SUPT20H,TRA2B,ZFP30,PPP1R9A,FRMPD1,CHD9,FBXO11,WDR37,ZNF365,FAM81A,URGCP,PPP4R3A,WDR47,SLC6A8,ZNF430,SEPHS1,SLC11A1,SHANK2,SLC12A2,SLC15A2,SMARCA4,SORCS3,SMARCE1,IFT122,ANKRD36,KIF13A,LMBRD1,SNRPN,PDZRN3,BDP1,SOX15,ZSWIM8,HECW1,MYCBP2,ZNF423,NFASC,LMO3,C11orf87,TAB2,ZNF621,POGZ,LARP4,KANK1,SULF2,SEPT3,STXBP1,FAM168A,SYT11,FGD4,PRRC2C,ARHGEF9,SYPL1,TAC1,MTCL1,CAMTA1,EXOC7,FAM208A,UNC5D,CNTN2,TBCEL,TMEM136,VWA3A,EHBP1,VWC2,KIAA0930,SATB2,TCF12,DOCK9,SLC19A3,TNS2,SIRT1,ITGB3BP,AP4E1,ASXL3,ZFP91,KAT6B,TP53BP2,TPM3,C9orf85,PPIL6,SSBP2,CLHC1,ZNF610,CADM1,RPL7L1,DNAJC12,PLEKHH2,USP1,VLDLR,RBFOX3,CLIP2,LAT2,NSD2,CLDND1,RICTOR,SLC13A3,XRCC4,ZNF711,ZNF17,MICU3,TRIM9,AGMO,ZNF138,ZNF142,REEP1,TMEM237,AMZ1,SMARCAD1,SLC30A4,PRDM10,HPS4,PCDH15,FIP1L1,HNRNPA3,TMEM63C,CASC15,ACTR3B,ADAMTSL3,NLRP3,ZNF248,NETO1,SOCS4,SLC4A10" MicroRNA hsa-miR-139-5p:mirSVR_lowEffct hsa-miR-139-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.06E-178 2.84E-174 6.05E-176 5.57E-175 447 1842 "SYN3,ARID1A,CSMD3,NDRG3,CCDC85A,GALNT13,ZNF608,MTUS1,PCDH19,SPARCL1,BBOX1,UNC79,SYT13,AMPD3,ZFAT,DPP10,ANK1,ANK3,CCDC146,LCORL,APBB2,APC,APP,SHTN1,LGR5,TMEFF1,CAPRIN2,DACT3,RASL11B,SLC4A4,ATP1B3,ATP2B1,ATP2B2,AZGP1,MPDZ,BCHE,FGF17,NRP2,DST,NAE1,LINC00906,MTMR2,IL33,CACNA1D,CACNB4,CABP7,KALRN,CANX,CH25H,PRC1,CERS5,USP6,INA,CBFA2T2,CD81,CDH2,CDH8,CDH10,LGI1,NOG,CACNA2D2,SRSF11,CHN1,CHN2,NDST3,RAB28,FAM19A5,MAP4K4,NIPBL,CNN3,FAM149A,AKAP6,SLC25A27,SLC4A7,SLC4A8,ABI3BP,CP,ENTPD4,RBM39,SNCAIP,TENM4,SEC24C,ARHGEF10,MICAL2,IPCEF1,PDE4DIP,PHACTR3,SLITRK5,DZIP3,PHF14,CTH,GREB1,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP32,ZNF337,KIAA0586,MAML1,IP6K1,PABPC5,BRINP1,ZNF804A,PLEKHM1,MYEF2,TIAM2,MFAP3L,MAGI2,ZC3H11A,SNAP91,RABGAP1L,CCDC3,DLX1,RAB39B,HS3ST4,DNM2,DPP6,RCAN1,EDNRB,FRY,GPR61,PHF20L1,APH1A,ABI2,GOLGA7,EML1,CALCRL,EMX2,EFS,DUSP27,ABCA8,EFEMP1,ST3GAL6,ZSCAN30,ZNF589,MED12L,OLFM1,PRKAG2,FHL1,MEX3B,FOXG1,CAP2,PCYOX1,RGPD5,SLC37A3,DCTN2,TACC2,TMEM107,ZBED3,HVCN1,UFM1,ARFGAP2,CAMKK2,ATP6V1H,KHDRBS3,CELF1,B3GAT1,SARAF,MEGF10,GABRA3,RAPGEF6,NCKAP1,GAP43,ATP8A2,ARFIP1,PPARGC1A,LYVE1,COPS8,SPIN1,RAB30,TOX3,INSM2,GNAL,GNAO1,FERMT2,GOLGB1,GPD2,GPM6B,GPR19,STON1,NUDT21,RAPGEF4,GRIA2,DIDO1,GRIA4,GRID1,NR3C1,GRM3,PRDM5,CIT,KIF3A,ZBTB49,AP4S1,PSIP1,ADAMTS6,WIF1,MAEL,HMGB1,HSF2,SHISA6,IGFBP1,KIAA1755,IL12A,INSM1,LRRTM3,NME9,JAK1,JAK2,KCNA1,KCNA4,KCNC2,KIF2A,KIT,KLC1,STXBP5,KTN1,STMN1,LIFR,SMAD1,PIK3AP1,MBNL1,MEIS1,SRSF12,KCTD6,MIA2,PPM1L,JAKMIP3,SCG3,RSPO2,MYCN,BEX5,NAP1L1,NEUROD1,NF1,NFIA,NFE2L2,NOVA1,HCN1,CHAMP1,CNTN3,PCSK5,PFKFB2,NALCN,ZNF655,SNX10,ZFYVE21,PKM,GPSM2,PCDH18,MTRF1L,PURG,STRN3,PRRX1,ING3,RETREG2,SEPT4,FAT3,POU3F2,MED1,MINDY2,LRRN3,CRLS1,PPP2R5C,PPP2R5E,PRKACB,MAPK10,HYDIN,DIRAS2,GDPD1,RELN,BCAS3,GON4L,MDGA2,PIGG,PLPPR1,PTHLH,PTK2,PTN,ZIK1,PTPN13,PTPRB,PTPRO,PTX3,ZNF844,USP47,SH3TC2,FAT4,RAP1GDS1,ARID4A,RBBP6,KHDRBS2,RET,REV3L,PRRT2,ERI2,UBR7,RGS7,SLC25A36,ZFHX4,C12orf49,CARF,ROBO2,RORB,TMEM100,NEK11,RPL15,MCMBP,GLDN,LGR4,PTGR2,RTN1,TRAPPC13,SALL1,SEMA6D,SATB1,ATXN7,SCN2A,SCN4B,LINC00461,SEC14L1,SELL,GALNT10,SFPQ,SGK1,ITSN1,SH3GL3,KIF16B,NTNG1,CHD9,FBXO11,FNDC3A,CNKSR2,SLC1A6,BTBD3,EPN2,DHX30,RAB3GAP1,SLC20A2,CPEB4,SMARCA4,SORCS3,RCOR3,SNRPN,TMCC1,MYO16,UNC80,SON,PDZD2,MYT1L,SOX2,BDP1,FNBP1,KDM3A,EMC1,MYCBP2,SPP1,TEX2,CDK19,LMO3,C11orf87,CLASP2,CAMTA2,EPB41L3,SS18,SEPT8,ADHFE1,SULF2,SEPT3,STXBP1,NECAB1,SYT11,FGD4,SYNE2,C3orf70,C12orf76,TAC3,TACC1,MTCL1,DDHD2,MCF2L,CAMSAP2,UNC5D,AGTPBP1,TBCEL,TBL1X,MGRN1,TCF4,TCF7L2,TPCN2,CLASP1,PHF24,RALYL,SLC19A3,VWCE,PMS2CL,ZFPM2,ITGB3BP,TGFBR3,SLC44A1,FBXL16,GZF1,ZFP91,HEY2,KAT6B,TNS1,SYNPO2,STXBP4,TRPC1,CA14,SSBP2,SGK3,TUBB1,SLAIN1,BCL2L13,VLDLR,KLC2,ETNPPL,XPO1,PCDH20,ZIC1,ZNF24,FMN2,PLPP4,ZBTB38,REEP1,TMEM198,DPYSL5,PLPPR5,EMSY,CADM2,RGMA,EVI5,PRDM10,SCG2,CIAPIN1,FIP1L1,WNK3,FAM13C,ST7,PHTF2,FBXO36,VANGL2,SSPN,FRMD6,NETO2,JPH3" MicroRNA hsa-miR-141:mirSVR_highEffct hsa-miR-141:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.22E-178 5.18E-174 1.08E-175 9.94E-175 420 1627 "ABCF1,SYN3,NCKAP5,CSMD3,ADD1,ADD2,ADD3,PLEKHH1,ADORA3,KIDINS220,BEND6,SLC44A5,RTL9,SMIM17,PCDH10,AMPD2,UPRT,ALS2,SHTN1,LGR5,MIER1,TMEFF1,ARNTL,CDK13,STK33,ASPH,ASTN1,ATM,STX16,ATP2A2,ADAM23,BACH1,NRP2,GPR146,ZNF599,ST3GAL5,MTMR2,JAZF1,GPC2,OSGIN2,WASF1,THSD7A,KALRN,PTBP2,SYT6,CAST,BRSK2,CCNH,USP6,SEPT7,CDC25B,CDC27,CDH10,L3MBTL4,TIGD7,DIS3L,CFL2,CHM,CHN2,PPT2,QKI,HECTD1,NIPBL,CNR1,COX4I1,AHCTF1,ACBD5,MYRIP,SLC35F1,CPS1,SEC31B,PREPL,CRMP1,RNF14,TRIM69,MROH8,ARHGEF10,CSNK1E,CSNK1G3,ATRNL1,VCAN,NCAN,PDE4DIP,PLXNA4,ERC2,APPL1,PHF14,CTNND2,NRSN1,ZSCAN23,DCAF4,EDRF1,KIAA0408,DOCK4,HDAC9,KIAA0586,DAPK1,DBI,ARMCX2,ZEB2,CEP170,TMEM130,LYPD1,RHOBTB1,SNAP91,SV2B,SPOCK3,GRIN3A,DYNC1I1,CPEB2,GNE,DYRK1A,ABCC5,ATL1,HIPK3,RBM12,YAF2,EGFR,KMT5B,GOLGA7,KCTD3,ELAVL2,ELAVL4,TMEM35A,PAN3,EPHB1,STX2,EPS8,IGSF6,ANKMY1,EYA1,DLC1,ST3GAL6,TESK2,FER,OLFM1,POLR1B,FGF13,SUCO,RGPD5,FLT1,NELFCD,SMC2,UFM1,TPK1,NPTN,KHDRBS3,CELF1,STAU2,MSANTD4,PHYHIPL,MEGF11,MEGF10,GABRA1,GABRA2,ZNF234,NEK6,C15orf41,GCNT2,PPARGC1A,TCERG1,GLI2,GLS,PCDH11X,ZNF638,CBX1,KDM2B,LOXL3,GPD1,GPD2,GPM6B,LILRA1,GPR12,PCLO,RAPGEF4,GRB10,GRIA2,GRIA4,ADAMTS13,ADAMTS8,GRIN2D,NR3C1,ATE1,GSN,KIF3A,PTPN5,GSTT2,LINC01551,GUCY1B1,GYG1,HPS5,NXPH2,MIER3,HLF,ACOT7,HMGB1,HNMT,HTR2A,HTR5A,EID2B,RBPJ,DIPK1A,INSM1,KCNJ11,KIT,IPO5,STXBP5,LAMP2,MAP6,MARK1,AQP11,MBNL1,MDM4,MEIS2,PPM1L,AFDN,CD200,COL28A1,SESN3,CCDC80,RSPO2,RTL5,NAP1L2,NAP1L3,NFE2L2,DNHD1,SLC11A2,NRCAM,HCN1,OGG1,P2RY1,GPR137C,PCDH8,PCDH9,PCSK5,PDCD2,PENK,BEST3,NALCN,ZNF655,PLCL1,EPN1,SMIM7,PNMA3,PMP2,TRHDE,SCHIP1,ING3,SPATA6,MED1,PPM1B,PPP2R5E,PRKACB,MAPK9,GDPD1,GON4L,CNTLN,PTCH1,MTMR10,PTHLH,SPDL1,TMEM260,PTPRD,PTPRE,PTPRG,PEX5,SH3TC2,FAT4,DBX2,KHDRBS2,MSANTD2,SLC6A15,ZMAT4,REV3L,TTLL7,SEC61A2,SETD5,RAVER2,TMEM100,NEK11,ADAL,TCP11L1,STK32B,LRRK2,LGR4,ATAT1,CLIP1,NCBP3,FAM192A,SATB1,ATXN7,SCN2A,LINC00461,SCP2,FNIP1,ELMOD1,SLC30A10,CASC3,SFPQ,SUPT20H,COPZ1,HSPA4L,ITSN1,DOCK10,NTNG1,CHD9,R3HDM2,ST3GAL3,SEC31A,SLC1A3,FAM81A,SLC1A7,URGCP,SEPHS1,CCDC88A,SLC14A1,SLC15A2,ATF7IP,TET1,CPEB4,RCOR3,ANKRD36,LIMCH1,RIMS1,MBD5,LMBRD1,SNRPN,RBM34,SON,PDZD2,MYT1L,SOX5,KDM3A,SP4,MCF2L2,RBM26,NPAS3,LMO3,TAB2,ATP10B,CLASP2,POGZ,ITPRID2,ZNF302,NKAIN2,MAPK8IP3,ZSCAN29,TTBK2,KANK1,SULF2,STXBP1,AJAP1,KLHL7,SYNE2,FNDC9,PLCB1,SYT4,TAC1,MTCL1,CAMSAP2,FAM208A,ADGRL3,TBCEL,FBXW11,TCF4,SIN3B,TCF7L2,ZEB1,TCF12,RALYL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,SIRT1,TIAM1,ZFP91,ERCC6L2,KAT6B,TPD52,METTL3,TSC1,RFTN2,RPL7L1,UBE3A,WIPF1,LAT2,CLDND1,RICTOR,SF1,ZNF711,ZNF17,ZNF19,MICU3,KCNT2,ANKS1B,SYNC,WNK1,EMSY,MFF,SLC17A6,GOPC,FAM13C,MRPL47,RTN4,HNRNPA3,PHTF2,CAMK1G,NUP214,NLRP3,ZNF248,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-659:mirSVR_lowEffct hsa-miR-659:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-177 1.74E-173 3.53E-175 3.25E-174 451 1883 "TTYH1,SERPINA3,SDE2,ACADM,NCKAP5,NBAT1,ACTN1,ARID1A,SLC25A25,CSMD3,FMNL2,TMEM132B,ADCY2,ADCY6,TMCC3,ADD2,SLC12A5,USP31,BEND6,DPY19L2P4,MTUS1,KLHL13,KCTD16,KIAA1324,WDR35,CEP126,FAM135A,SYT13,AMPD2,AMPD3,DPP10,ANK1,CCDC146,ARMC12,MAP4K3,USP28,GPAM,DGKD,TNRC6C,API5,LGR5,ARHGAP5,ARNTL,CDK13,BRINP2,CCAR2,EIF4G3,ATP2B3,SLC2A11,DPY19L3,MPDZ,CFLAR,BMPR1B,ST3GAL5,NAE1,JAZF1,GPC2,CA12,CACNA1A,CACNA2D1,CACNB4,CALB1,CAPN3,CH25H,PRC1,CLDN10,KYAT1,KRIT1,SLC16A4,ENTPD6,ARHGEF2,CDC27,EVI5L,DLGAP2,CDO1,NUMBL,SRSF11,FOXN3,KMT2C,EPS15L1,IGFBP7-AS1,PPT2,CLCN4,NGEF,C4orf33,SULT4A1,PCYT1B,AKAP6,LETMD1,ABI3BP,AHCTF1,SMARCAL1,SEC31B,CREM,RBM39,CRHBP,CRMP1,SNCAIP,RGS6,LRRC3B,OSBPL3,SUSD5,VCAN,CST3,PITPNM3,PNPLA8,RIMS2,ZSCAN23,RUBCN,ARHGAP32,FRMPD4,TOX,PHF19,KIAA0513,MATR3,DGKB,DAPK1,SCRN1,GIT2,DCC,ARMCX2,C8orf34,ZEB2,MFAP3L,HP1BP3,BLOC1S6,ZC3H11A,POM121,RHOBTB1,PLPPR4,SNAP91,SV2B,SPOCK3,SV2A,SRGAP3,CCDC3,EXOG,USP3,NR1D2,DOCK2,DPYSL2,SLC25A18,GNE,ECM2,GOLT1B,AASDH,USH1C,EDNRB,RASGRP1,KLHL5,EFNB3,PHF20L1,COPS4,PLEKHA1,TNK2,MRNIP,C8orf37,EPB41,GPHN,RABEPK,STX2,SRRM1,MRPL37,MRPL10,CACNG3,ACSL4,PTK2B,TAOK3,EFEMP1,ST3GAL6,CHST15,TESK2,FER,OLFM1,FGF13,FHL1,POLK,SUCO,HPCAL4,SYNCRIP,FLT1,SGIP1,EFCAB2,SORBS1,HVCN1,UFM1,PDLIM5,FAM49B,ATP6V1H,ERGIC3,CELF1,DACH2,ST6GALNAC3,MSANTD4,NRG3,OGA,PHYHIPL,MEGF11,MEGF10,GABRA2,GABRG2,FAM184B,GALC,RAPGEF6,ERAP1,SRRM4,GATM,ZNF276,GLI2,GLYR1,ZNF638,LUZP2,DCLK2,RFFL,GRIK2,GRIN2D,GRM1,PRDM5,GRM7,CIT,BVES,AP4S1,PSIP1,RNFT2,ADAMTS6,NXPH2,FRMD3,ARHGAP19,HNF4G,ZNF491,OPALIN,HSF2,HTR2A,SOWAHA,NKD1,RBPJ,NIM1K,DOCK7,IL6ST,ZNF678,LRRTM3,NME9,ITIH2,JAK1,SLC35G1,KCNJ3,KCNJ10,KCNK2,STXBP5,STMN1,LMO2,PIK3AP1,MAN2A2,AQP11,MBNL1,LDLRAD3,POC1B,MITF,WDR49,ADAM22,MSR1,PTOV1,MTR,MXI1,LYRM9,PABPC1L2A,MYT1,TCEAL5,ZC3H12B,NDP,IDNK,NEFH,NF1,NFE2L2,NFIX,PCBP3,CHAMP1,CLDN11,ZNF713,GLIPR1L2,PCDH9,PCMT1,PCSK5,CDK18,PIRT,ENPP2,GNG2,PIK3R1,RETREG1,PLCB2,PLEC,PLIN1,LRP12,PRRX1,ING3,RETREG2,FA2H,POLG,NXPH1,MED1,PPM1B,LRRN3,PKIA,PKN2,GRAMD1C,CNNM2,CNTLN,PLPPR1,BDNF-AS,PTPN13,PTPRD,PTPRZ1,PEX2,TTC13,CEP97,SUSD4,RAP1GDS1,ENOX1,RASGRF2,RFX2,RIC8B,RNASEL,ALG9,PNMA8A,KIRREL1,CCDC25,RPE65,SPIN3,ATP8B4,HUNK,KCNIP1,ZNF354C,AP1AR,FOXRED2,ATXN7,LRRTM4,SCN8A,SCP2,PEAR1,SOX6,SH3BGR,KIF21A,ARX,FERMT1,NTNG1,MAGI3,AMBRA1,FBXO11,ANKRD6,ZNF365,SLC6A1,LRRC55,SLC6A8,KDM4D,CCDC88A,SLC12A2,SLC14A1,NAPB,ATF7IP,SLC22A4,TET1,SMARCA4,RIMS1,MBD5,KIF13A,SNRPN,PALLD,DOP1A,SON,WDTC1,SOX1,HECW1,TEX2,IDI2-AS1,PEG10,BEX1,LHPP,SSTR2,EPB41L3,SS18,STAU1,SEPT8,ADHFE1,SYNE2,NUDT10,UNC5D,VWA3A,VWC2,TCF4,SIN3B,SATB2,CUX2,RPGRIP1L,SZT2,SLC19A3,OBSL1,NSD1,ARHGEF12,TEX15,RNF216P1,FAM200B,PMS2CL,CRB1,GPR161,TGFBR3,AKTIP,NR2E1,TNR,TPD52,TPM2,DOK6,SYNPO2,PDSS1,TRO,ZMYND8,DCBLD1,SSBP2,TTTY15,RFTN2,FAM155A,SLAIN1,VLDLR,BEST1,ETNPPL,ZBTB14,ZNF45,FMN2,ZNF154,FSTL5,EML6,ANKS1B,ZNF213,SYNC,WNK1,MFF,CADM2,PRDM2,SCG2,GAL3ST3,NAV2,SLC17A7,KCNAB1,ITM2C,SLC17A6,CASC15,TIGD6,RNF170,SSPN,CBLN2,CPNE4,FAM198A" MicroRNA hsa-miR-448:mirSVR_highEffct hsa-miR-448:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.15E-177 1.77E-173 3.53E-175 3.25E-174 419 1624 "RALGAPA1,AS3MT,FMNL2,KLHL32,ADD1,ADD3,SORCS1,PWWP2A,KIDINS220,DPY19L2P4,HECW2,CC2D2A,AK2,C1QTNF3,SPARCL1,ABCD2,DOC2A,OGT,ANK3,USP28,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PARG,CNTNAP1,UPRT,GPAM,API5,MIER1,SFMBT2,ZFYVE28,ARNTL,CDK13,ASPH,NCOA1,NUMB,ATM,ATP2B2,ZNF582,DPY19L3,MPDZ,DCAF5,DST,SYNJ1,SCAPER,OSGIN2,CALB1,ZNF555,KALRN,PTBP2,CAST,CLDN10,INA,SCARB1,SEPT7,CDC42,CDH10,LGI1,CFL2,SRSF11,CHM,CASC2,SYNPR,NDST3,SULT4A1,TMEM155,IGLON5,CNR1,ARMC8,COL4A5,MYRIP,ZNF521,ZFP28,HS3ST5,CREM,RBM39,RNF14,CLIP3,FEZ2,OSBPL3,ATRNL1,SOCS5,SLITRK5,DZIP3,APPL1,PHF14,CTNND1,CTNND2,USP6NL,CCDC144A,BOC,DOCK4,TCAF1,ARHGAP24,FRMPD4,TOX,ZFYVE16,EARS2,LIN54,DAPK1,BRINP1,GIT2,DCC,DNAJC6,ZNF804A,ZEB2,MYEF2,COPS7A,KIAA0319,BLOC1S6,GSDME,SPOCK3,DYNC1I1,NR1D2,CPEB2,CASP8AP2,DPYSL2,ABI1,DTNA,MAMLD1,ABCC9,GOLT1B,EBF1,ANKRD46,RASGRP1,KLHL5,TMTC1,MBNL2,EGR3,AASS,ELAVL2,PLEKHA1,CALCRL,PAN3,LRRC17,EPHB1,KCNMB2,GPHN,SRRM1,DENND4A,ETV1,F8,ARMCX1,CLVS1,SH3YL1,ACSL4,CHST15,FER,KIAA1109,SUCO,MEX3B,SEC23B,ATP13A4,FLT1,SLC37A3,NBEA,SMC2,HVCN1,PDLIM5,CELF1,NRG3,ZNF512,FYB1,PHYHIPL,ZNF44,GABRB3,ZMYND11,RAPGEF6,ARPP21,NEK6,IP6K3,C15orf41,DISC1,GATM,SULT1C4,MSTN,GLRB,MSL3,KDM2B,HTATSF1,RAB40B,FERMT2,GPM6A,PCLO,RAPGEF4,GRIK2,PRDM5,KIF3A,FAM19A2,ZBTB49,GUCY1A1,ZHX1,LINC01102,SCRG1,HNF4G,ZDHHC15,CELF5,SMAP1,EID2B,ZNF181,ZNF546,PLD5,SCIN,INPP5B,ITPKB,JAK1,KCNA4,KCNB1,KCND2,KCNJ3,KCNK3,STXBP5,PAXBP1,HECTD2,PACRG,PIK3AP1,MARK1,MAT2A,MATN3,MBD1,MBNL1,SHC3,MEF2C,MEIS1,MITF,MOBP,ADAM22,MXI1,MYH3,NEK1,CNOT4,NOVA1,NOVA2,NPR2,NRCAM,SMIM11A,NUCB2,SETD4,GLIPR1L2,CNTN3,PAX6,PCDH8,PCDH9,PRTG,PDE4D,PDGFRA,GPR85,SERPINE2,SSH1,PIK3C2A,ANLN,FAM216A,SMIM7,MTRF1L,SCHIP1,ING3,SPATA6,SH3KBP1,MINDY2,CRLS1,PPP2R5C,PPP2R5E,PRKAB2,PRKCB,PKN2,GDPD1,DCHS2,SAMD9,LRRC49,DEF8,GON4L,SNRK,BDNF-AS,PTPRD,EML5,PTPRE,PTPRH,QDPR,RAB5B,CEP97,USP47,RAD51D,ZNF793,OXR1,SLC6A15,REV3L,ERI2,RFX4,TTLL7,KIF7,ZFHX4,ROBO2,RORB,ARMH4,UEVLD,SPIN3,ABCA11P,WLS,ZNF568,AMER2,SATB1,ATXN2,HSPA4L,SCAF8,ITSN1,SH3GL2,CHD9,FNDC3A,NLGN1,ANKRD6,ABLIM3,SLA,WDR47,RUFY2,KDM4D,SLC12A2,CPEB4,ZFP1,ANKRD36,LIMCH1,RIMS1,PALLD,TMCC1,UNC80,SOX1,ZCCHC24,ENKUR,EMC1,DBNDD2,CDK19,RBM26,NPAS3,LMO3,C11orf87,SRPK2,ZNF302,SAMSN1,SS18,NXT2,RGL1,AJAP1,FGD4,PLCB1,SYN1,TMEM150C,SYN2,COBL,ANKRD28,SYT4,ATP11A,TACC1,PJA1,TBCEL,ANO4,EHBP1,RPGRIP1L,DOCK9,PUM2,USP32P1,FRYL,TEK,SIRT1,ZFPM2,CRB1,HHIP,TJP1,TLR4,ERCC6L2,HEY2,TMOD1,R3HDM1,PARD3,C5orf64,NPL,RGMB,SYNPO2,ANO5,CLHC1,AMOT,PLEKHH2,VLDLR,TBC1D15,WIPF1,RICTOR,ZNF711,MICU3,AGMO,ZNF74,TCEAL7,CELF4,SPIRE1,UPF3A,WNK1,CADM2,SLC38A1,CSDE1,RNF103,HPS4,PCDH15,PPP1R3F,KCNAB1,TMEM163,FAM47E,MVB12B,C12orf4,PDSS2,FAM13C,FZD3,FBXO36,JMJD1C,ZNF248,SSPN,FXR1,FRMD6,IFT88,NETO1,SLC4A10,GAN,ZNF30,JPH3" MicroRNA hsa-miR-454:mirSVR_lowEffct hsa-miR-454:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.73E-177 3.22E-173 6.32E-175 5.82E-174 440 1795 "KCNH8,ASIC1,SYS1,ACTN1,CSMD2,ADD1,PWWP2A,PCDH19,CC2D2A,AK2,LRRC7,SPARCL1,BCAR3,PCDH10,PITPNM2,AMPD3,ZFAT,SEMA7A,CCDC146,MAP4K3,MYH7B,PHF12,PPFIA2,EPB41L5,TNRC6C,SHTN1,LGR5,IGDCC4,ARHGAP5,CDK13,ASCL1,ATM,ATP1A2,ZNF582,MTMR9,B3GALT2,DOCK11,KSR1,BMPR1B,CDK5R1,LINC00906,SGCE,NIPA1,RAB29,LDLRAD4,CALB1,CAMK2D,CANX,VSTM2A,USP2,ENTPD6,CDC42,ZMYM4,MAGI1,NOG,SRSF11,FOXN3,CASC2,MS4A7,EPS15L1,COG1,FBXO7,C4orf33,QKI,HECTD1,MAP4K4,RAB26,FHL5,IQCK,SLC25A27,AKAP5,SLC4A7,SLC4A8,ZNF521,PNKD,CREB5,HAPLN1,FEZ2,MICAL2,FAM169A,DZIP3,ERC2,DOCK4,MYADM,KATNAL2,GAPVD1,SNPH,ARHGAP24,ZNF337,RASSF2,MATR3,MAML1,DGKG,TMEM170A,CTIF,GIT2,DNAL1,DBN1,PITPNC1,ZNF804A,MAGI2,KLHL3,SNAP91,SV2B,AK5,G3BP2,FAM107B,DLG2,DLG3,GRIN3A,NYAP1,USP3,DNAH9,MED12,DNM2,CPEB2,SLC12A6,SLC25A18,GNE,DTNA,ECM2,DNAJB6,DNM1L,EDIL3,SNX29,HIPK3,FCF1,TMTC1,FRY,EIF4G2,TENM1,C3orf18,EMX2,LRRC17,EPHA5,GPHN,ETV1,TLR7,KATNAL1,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CHST15,FECH,OLFM1,AMOTL2,CAMSAP1,MEX3B,FOXG1,PCYOX1,ANKFY1,NOP56,JKAMP,TACC2,STAU2,DKK3,GAB1,GABRA3,ZNF44,GABRG1,CAB39,ZMYND11,GALC,RAPGEF6,ZNF274,IQGAP2,TUBGCP4,PCDH17,PPARGC1A,DBF4,TOX3,GPT2,ADGRA3,ATF7,FUT10,GPR12,MCHR1,GPER1,CECR2,PCLO,GRIA2,GRIA4,GRIK1,NR3C1,GRM2,LINC01089,KAT7,LINC01551,SOX21,GUCY1A1,MAP4K5,FAM222A,CELF3,RASSF8,HAS2,HPS5,FRMD3,MIER3,HLF,SCRG1,IGF1,NIM1K,DOCK7,LIX1,LRRTM3,SLC35G1,KCNA4,KCNC2,KCNJ10,KCNK1,KCNN2,KIF5C,KIT,NCOA7,C2orf80,MAP2,MARK3,ADAM11,CHIC1,LDLRAD3,AFF1,WDR49,ZNF680,ADAM22,SCG3,MXI1,MYH6,MYO5A,MYO9A,NEXMIF,PABPC1L2A,NAP1L1,NAP1L2,NCAM1,NDUFA5,IDNK,NOVA1,NPTX1,NPTX2,HCN1,NUMA1,OGDH,OLR1,OPCML,KCNK10,DPY19L2P2,PDE1A,PDE4B,PDE4D,CYTL1,PFKFB3,PIK3C2A,PIK3R1,FAM216A,PDZRN4,STRN3,RC3H2,ING3,SH3KBP1,POU6F1,PPM1B,PPP3CB,PRKAB2,PKIA,HYDIN,DIRAS2,RELN,VPS13C,DEF8,MDGA2,ZIK1,PTPRD,PTPRE,TMEM231,PPP2R3C,USP47,PLEKHB2,FAM184A,ROGDI,OXR1,RBBP6,BSDC1,GTDC1,FIGN,RFX3,RFX5,UBR7,RNASEL,EXD2,ROBO1,RORB,ELP2,TMEM100,UEVLD,ZC3H14,ZNF671,GLDN,PRR5L,LGR4,YJEFN3,RYR3,ZNF331,FAM182A,SATB1,SCN4B,SCN8A,LINC00461,SCP2,TNFRSF19,SELL,HSPA4L,PUF60,ITSN1,CPEB3,DOCK10,AMBRA1,FNDC3A,R3HDM2,NUBPL,ZNF365,FAM81A,CDK5RAP3,SLC12A2,EFHD1,CPEB4,MAST1,RCOR3,RIMS1,CABCOCO1,SNRPN,SON,TNIK,KIF21B,FNBP1,KDM3A,EMC1,KIF1B,TSPYL2,RBM26,NPAS3,C11orf87,EPB41L3,ZC4H2,LARP4,STAU1,SEPT8,DIP2A,KANK1,STXBP1,AJAP1,MLC1,VAMP1,SYT1,SLC37A2,SYT4,TAC1,ATP11A,TACC1,TACR1,KAZN,EXOC7,PDLIM2,AGTPBP1,TBCEL,TBL1X,TMEM136,ATMIN,TCEA1,TCF4,SIN3B,DMXL2,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,WDR7,AZIN2,SYNE1,PCDHB7,ARHGEF12,USP32P1,FRYL,GALNT17,ZFP91,HEY2,RIMBP2,PARD3,RBFOX2,NPL,DOK6,NR2C2,TRPS1,HIRA,EIF4ENIF1,UBE3A,LINC00689,VAV2,TOM1L2,VLDLR,P2RY12,NSD2,CLDND1,RICTOR,XRCC4,PCDH20,ZNF24,SLC26A10,CELF4,SPIRE1,UPF3A,EMSY,CSDE1,EVI5,LINC02210,PRDM10,NAV3,SNX27,FIP1L1,FAM47E,SLC17A6,PDSS2,FAM13C,DOCK8,RTN4,FBXO36,CASC15,FAM219B,ADAMTSL3,JMJD1C,ZNF248,RNF170,PIANP,NETO2,NETO1,SOCS4,SLC4A10,JPH3" MicroRNA hsa-miR-491-5p:mirSVR_lowEffct hsa-miR-491-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.99E-177 3.37E-173 6.47E-175 5.96E-174 448 1861 "SERPINA3,ACADM,ACHE,EMILIN3,FAM43B,CSMD2,GPRIN1,SLC25A25,PLEKHG5,TMCC3,ADD1,PLEKHH1,GRAMD1B,FZD9,KIAA1211,LRFN2,LCNL1,MTA3,SLC24A4,INTS2,HECW2,C1QTNF3,SEMA6A,ALCAM,LTBP4,SYT13,OGT,ANK1,GAS7,APLP1,GPAM,CDK10,MADD,ARRB1,ARRB2,PDE8B,MARCH3,DACT3,NUMB,ASTN1,ATP1A2,ATP2B3,ATP6V1G2,ATP6V0A1,TTLL9,ADGRB1,SNAI3-AS1,BCHE,RGS11,GPR146,KSR1,BMPR1B,DST,SYNJ1,ARHGEF7,FUBP1,MTMR2,C1QC,AP1M1,CDK5R2,BTRC,CACNG1,CAMK2B,SPAG9,PRC1,CERS5,CBFA2T2,CD38,ENTPD2,CDC27,IGFN1,NOG,CFL2,GPR37L1,ADGRG1,ASIC3,CHRNB2,TAOK2,LHX2,DLGAP3,EPS15L1,CPNE6,NRXN2,CLTC,FADS2,VAX2,IGLON5,CNTN1,FAM149A,COL9A2,COL11A2,TBPL1,ACBD5,ENTPD4,NCOR2,GDA,CLIP3,CS,SNCAIP,CSF1,SEC24C,SUSD5,KIAA0040,CTH,CTNND1,EDRF1,PHF19,ZNF337,LIN54,MAML1,IST1,DGKG,SPOCK2,ELMSAN1,DCTN1,CNIH3,C2CD2L,KIAA0319,MAGI2,TMEM130,PLPPR4,SACS,SPOCK3,SV2A,SRGAP3,SGSM2,G3BP2,KBTBD11,DLG2,DLG4,HS3ST4,DMPK,DRP2,GNE,TOM1,DYRK1A,E2F5,SYT15,CNNM1,SIDT2,EFNA3,YAF2,EFNB3,PHF20L1,APH1A,EGFR,MRO,EGR3,SORBS3,ING4,ELAVL4,ELN,USPL1,VPS13B,EPB41,SLC43A2,SRRM1,ERBB2,NCALD,EFS,SPEG,CDHR1,ETV1,EXTL1,CEND1,MRVI1,PTK2B,TAOK3,CHST15,TOMM40L,FCGRT,FKTN,ZSCAN30,TESK2,KAT8,SPSB4,FGR,MEX3B,HPCAL4,CAP2,AGAP2,AGAP3,RGPD5,EFCAB2,PDLIM5,CAMKK2,STAU2,ADGRA1,TMEM151A,TBR1,DOT1L,SDCBP2,NEURL4,DKK3,TRAF3IP2,ILDR2,BRPF3,GALC,B4GALNT1,GHDC,IQGAP2,SIGLEC8,ALDH1L1,SRCAP,SESN1,GGT7,GHR,CRCP,GLI2,GNAS,LNX1,ADGRA3,GPD1,B4GALNT4,PCLO,STMN2,GRIA4,GRIK1,GRM7,FAM19A2,RNF165,TMEM25,LINC01551,RABL2A,FAM107A,UBE2QL1,PADI2,NXPH3,ATXN2L,MIER3,HLF,HMX1,CPT1C,LRRC75A,SHISA6,CELF5,SMAP1,HTR5A,ICA1,MSL1,IDH3B,MYLK2,RAB41,LRRC25,TJAP1,USP54,IL6R,IL6ST,SCRT2,DIPK1A,ITPKA,METTL21A,KCNH2,KCNJ9,KCNK2,KCNN3,KIF5A,A1BG-AS1,L1CAM,HECTD2,FGFBP3,SYT9,MEIS1,MEST,POC1B,MOBP,ERICH3,DBNL,MSRA,PTOV1,MYH6,RTL5,ZNF862,HNRNPM,SLCO1C1,NHLH1,NOVA1,NUCB1,CHAMP1,OPHN1,PAH,PBX1,DPY19L2P2,PIRT,PDYN,GPR85,ZDHHC8,PIK3R1,PKM,FAM216A,EPN1,PLP1,SLC25A23,HMGCLL1,PURG,EXOSC10,EPB41L4B,POU3F2,POU6F1,PPARA,CRLS1,PPP2R5C,KANSL1,CEP41,PRKAR1B,PRKCB,PRKCZ,MAPK4,DIRAS2,DCHS2,MASP1,WBP1L,GDPD2,CNTLN,TMEM260,CASTOR1,PTPRH,NKAIN1,RAB3A,RAB3IL1,CEP97,SLC25A48,CCDC40,RASGRF2,ZDHHC14,BSDC1,DPF2,GTDC1,ZDHHC4,RGS12,PRIMA1,SLC25A36,RIC8B,CCDC82,SETD5,MYH14,KLHDC8A,ARMC5,CARF,CCDC25,RPE,SNX22,BAALC,GLDN,SGSM1,ACER3,PAQR6,ST6GALNAC6,KCNIP2,RXRG,NCBP3,ZNF331,PRCD,FNIP1,TNFRSF19,SELL,CASC3,FOXRED1,R3HDM2,FAM81A,BTBD3,SLC6A7,SLC6A8,SLC11A1,ELMO2,BTBD7,SPHKAP,NAXD,SLN,CDK5RAP2,IGSF9B,MBD5,CABCOCO1,SNRPN,UNC80,KDM4B,SCN3B,SOX2,KIF21B,SP2,ZSWIM8,MYCBP2,PEG10,SPTB,TAB2,CLSTN2,MPRIP,STAC2,STX1A,SEPT3,GSE1,SYT11,VAMP1,PLCB1,SYN1,SYP,PJA1,CAMTA1,EXOC7,DMXL2,CUX2,TPCN2,PCDHB15,SLC19A3,AKNA,SIK3,CYB561A3,RNF216P1,CRB1,ITGB3BP,FBXL16,LRRC8A,TNFRSF1B,R3HDM1,TNS1,RASD2,TPM2,PDSS1,DCBLD1,RUSC1,TSN,HSPBP1,SLC35A4,CLEC2L,UBE3A,PLPPR2,TOM1L2,WIPF1,CLIP2,ZNF74,GPR158-AS1,NDRG4,SLC26A10,CELF4,ANKS1B,EMSY,PRDM2,PRTFDC1,PRDM8,PCDH15,PCBP4,GOPC,CASC15,CERS6,NHSL1,KLHDC1,LAS1L,PRRT4" MicroRNA hsa-miR-205:mirSVR_lowEffct hsa-miR-205:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-176 6.22E-173 1.17E-174 1.08E-173 462 1981 "ABCF1,KCNH8,NCKAP5,ARID1A,RNF157,ADD1,AXIN2,ERMN,ADORA1,ESYT2,ADRB2,GPR158,PCDH19,NME5,WDR35,OSBPL8,C1QTNF3,PCDH10,FAM135A,SYT13,AMPD2,CDC42BPA,SEMA7A,C6orf89,PI16,PHF12,APBA2,GPAM,DGKD,PPFIA3,USP37,APP,SHTN1,LGR5,PRX,IGDCC4,ZFYVE28,PDE8B,CAPRIN2,NCOA1,SLC4A4,ATP2B3,SLC2A11,ALDH7A1,MTMR9,B3GALT2,ADAM23,ADGRB2,ADGRB3,BARD1,SEC11C,DCAF5,BMPR1B,FUBP1,NAE1,MTMR2,SGCE,CA8,THSD7A,CALM1,CANX,USP6,MTMR7,C1orf52,LRBA,CDC25B,CDC42,CDH10,DCLK1,ZMYM4,L3MBTL4,LOC730101,DLGAP2,TIGD7,RCBTB2,TAOK2,KMT2C,RAB28,NRXN3,IGFBP7-AS1,C4orf33,NIPBL,IGLON5,CNN3,AKAP7,FAM149A,AKAP6,SUMF2,BTF3L4,ABI3BP,COX4I1,MYRIP,ZFP28,CHD1L,SEC31B,CDC42BPB,PREPL,CREM,ABCG1,SNCAIP,CSF1,FEZ1,CNTNAP2,PLXNA4,NRSN1,PUM1,RIMS2,RUBCN,GAPVD1,ZNF337,KCTD8,PHYHIP,BRINP1,AIF1L,GIT2,DCC,ELMSAN1,JAKMIP2,ZEB2,ZBTB24,MYEF2,FBXL5,KIAA0319,CEP170,MAGI2,BLOC1S6,ZC3H11A,SMG7,KBTBD11,DLG2,EXOG,DMD,HS3ST4,USP3,DNAH9,SLC29A4,DOCK2,DMTF1,DRD1,ACOT8,PDCD6IP,ECM2,ABCC5,E2F5,EBF1,EDIL3,EDNRB,HIPK3,FRY,PHF20L1,RASA4,ELAVL2,C3orf18,USPL1,EPB41L1,LRRC17,STX2,SRRM1,TMEM74,ETV1,MRVI1,HSPA12B,PTK2B,ZIC4,CEP78,FDFT1,SLC9B2,FGF1,FGFR1,PRKAG2,FHL1,SUCO,UBE2E3,PCYOX1,VTI1B,SYNCRIP,WDR83,USP16,UFM1,FAM49B,ZNF605,CELF1,DACH2,HHIPL1,AP4B1,OGA,GAB1,GABRA1,GABRA2,GABRB1,CAB39,GAD1,ZMYND11,GALC,ZNF234,NEK6,IQGAP2,ERAP1,ATP8A2,MSTN,ADAM28,RND1,DBF4,GLS,LUZP2,FERMT2,WDFY3-AS2,GPD2,PRUNE2,MCHR1,GPR34,GRIK3,NR3C1,ATE1,GRM3,GRM7,CLASRP,KAT7,PSIP1,IRAK3,INSYN1,ARHGAP36,HMGB1,HNMT,NEGR1,OPALIN,LRRC75A,HTR2A,HTR5A,EID2B,ZNF181,IGF1,NKD1,ZIC5,KNDC1,SCIN,IL6ST,IBA57,BRINP3,INSM1,METTL21A,KCNC2,KCND2,KCND3,KCNH2,KCNJ10,KCNK2,KIF2A,STXBP5,KTN1,INSYN2,HECTD2,ARHGAP12,MAP6,MAT2A,SYT9,CHIC1,TM6SF1,LRP1B,KITLG,PPM1L,POC1B,AFF1,AFDN,MOBP,MRPL42,SAMD5,DDX25,MTTP,MX1,MYCN,LYRM9,MYO9A,NF1,NFYA,NODAL,DNHD1,SLC11A2,NRGN,NUCB2,OCRL,OMG,P2RX7,ZDHHC22,GLIPR1L2,PAK3,PCDH9,PCSK1,PIRT,FAM98B,CAMKV,PLP1,HMGCLL1,PMP2,CDIP1,ING3,SPATA6,NXPH1,MED1,PTPA,PPP2R5C,RASGEF1B,PRKCZ,MAPK3,GDPD1,RELN,LRRC49,SIDT1,GDPD2,MDGA2,CNTLN,PTCH1,BDNF-AS,MTMR10,PTHLH,SPDL1,STK32A,FAM120C,PTX3,CEP97,RAD17,SH3TC2,RASGRF2,ARID4A,ZYG11B,GTDC1,RFX5,LGI2,TMLHE,ROBO2,TMEM206,ELP2,CCDC102B,RPE,NEK11,ARMH4,ZC3H14,ATP8B4,RPS6KA2,HUNK,KCNIP2,RYR3,FAM182A,TRAPPC13,AP1AR,RMI1,HOGA1,SCN7A,SOX6,RASA3,PPM1E,KIF16B,CPEB3,NTNG1,FNDC3A,CNKSR2,ZNF365,FAM81A,PPP4R3A,LIMS2,SLC6A1,KANSL3,PKNOX2,LRRC55,KBTBD4,SLC12A2,SCMH1,BTBD7,SLC20A2,GKAP1,SORCS3,MBD5,SNRPN,PDZRN3,RBM34,KDM4B,FAM219A,SON,BDP1,HECW1,MYCBP2,PEG10,KIF1B,TSPYL2,C11orf87,ITPRID2,EPB41L3,ZC4H2,ELOVL4,NEK4,SEPT8,STXBP1,NSFL1C,SYNE2,VAMP1,DDHD2,CAMTA1,TBL1X,TMEM136,MGRN1,ANO4,TBX15,TCF7L2,TRIM2,RPGRIP1L,USP22,FRYL,SIK3,FAM200B,ZFPM2,SPX,C18orf54,ITGB3BP,LEFTY2,CDH22,ACTR6,TLL2,HEY2,CSMD1,KAT6B,RBFOX2,C9orf85,ZNF346,PRMT8,TRIO,PDSS1,TRPS1,FNDC5,SGK3,LINC00689,PLEKHH2,BCL2L13,RBFOX3,CLIP2,ZNF781,NSD2,GUSBP1,XPO1,ZIC2,ZNF24,LYPD6,ZNF154,PLPPR5,EMSY,LINC02210,STOX2,PRDM8,FIP1L1,PLSCR4,RGS7BP,FZD3,DOCK8,RTN4,UBE3B,FBXO36,NUP214,ACTR3B,ZNF248,NHSL1,IFT88,NETO1,SOCS4" MicroRNA hsa-miR-3151:mirSVR_lowEffct hsa-miR-3151:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-176 7.58E-173 1.40E-174 1.29E-173 446 1848 "ABR,SYN3,ASIC1,NBAT1,SYS1,FAM43B,SLC25A25,DSCAML1,TMCC3,RNF157,ADD1,PLEKHH1,UNC5A,PTCHD1,ADRA1D,OLMALINC,MTA3,AP2A2,ZNF608,HECW2,TXNDC16,PLA2G6,SEMA6A,PCDH10,LTBP4,GOLGA7B,MRTFA,PITPNM2,AMPD2,AMPD3,LRFN1,OGT,PI16,MYH7B,PHYHD1,SEMA4G,IGDCC4,ARHGDIA,LINC00173,MARCH3,ASPH,PCDHGB4,ASTN1,TMEM108,CHID1,ATP1A3,RNF182,MTMR9,CFLAR,ARHGEF7,BTK,JAZF1,C1QC,GPC2,MYRF,CACNA1D,DDR1,CACNA2D1,CACNG1,CALB2,CABP7,CALM1,KALRN,CAMK2A,SYT6,CAST,MTMR7,CBFA2T2,SCARB1,SYNGR3,ZMYM4,EVI5L,L3MBTL4,TIGD7,NOG,CACNA2D2,CHRM1,CASC2,SYNPR,TAOK2,LSMEM2,LHX2,DLGAP3,NRXN2,CLTA,TMEM59L,DNAJB5,IGLON5,IQCK,FAM149A,COL9A2,COL11A2,CREM,SH2B1,ANKRD44,CSF3R,CSNK1E,CST3,SLITRK5,SDC3,CTH,GREB1,GPSM1,CYBB,MYADM,ARHGAP32,RIPOR2,ARHGAP24,PHF19,TM9SF4,TBC1D5,INTS1,MAML1,SPOCK2,CTIF,AIF1L,PITPNC1,RUSC2,TMEM130,ZC3H11A,SGSM2,RABGAP1L,TMCC2,MED12,SLC29A4,NR1D2,DTNA,DYRK1A,E2F5,EDN1,SYT15,FRY,SIDT2,EFNB3,EGR3,TMEM132E,SORBS3,TENM1,ELAVL4,BSCL2,C3orf18,ENO2,EPB41L2,LRRC17,ANKRD13B,RAB9B,ERBB2,DUSP27,RCSD1,ANKMY1,MRVI1,EZH1,HSPA12B,REEP2,CLVS1,TUBB4A,FCGR1A,ZMYND10,TOMM40L,FCGRT,TESK2,FGF11,FGFR3,MEX3B,HPCAL4,IP6K2,AGAP3,EVL,C2orf88,DPYSL4,TMEM107,TRIM16,RASL10A,CAMKK2,KHDRBS3,GPR153,ST6GALNAC3,CSPG5,ADGRA1,NRG3,TVP23A,FYN,NEURL4,B4GALNT1,INPP5K,ACSS1,GCK,GFAP,ADAM28,CSDC2,GGT7,GGT5,NTNG2,STARD3,INSM2,POLL,GNAS,LNX1,DIDO1,GRIK3,GRM2,ZNF496,ZBTB49,RABL2A,LINGO1,SLC2A6,UBE2QL1,ARHGAP19,AGBL5,HNF4G,NEGR1,SHISA6,SMAP1,IDH3B,MYLK2,ZNF546,NKD1,DOCK7,KIAA1755,INPP5B,KCNB1,KCNH2,KCNK3,KCNN1,GATD1,KHK,KIT,L1CAM,LRRC4B,STMN1,SFXN5,PIK3AP1,SYT9,MDFI,CHIC1,MT3,TMEM249,MX1,LYRM9,LAYN,P2RY13,NFIX,NNAT,NME4,NODAL,DNHD1,NPTX2,NUMA1,OCRL,OGDH,OGG1,OPA1,ZNF827,PBX1,DPY19L2P2,PCDHGC3,PCSK2,CDK18,PDE2A,PFKP,SEMA5B,FAM218A,PKM,SLC25A23,PCDH18,ASPDH,MAPKAP1,EXOSC10,RETREG2,POLG,TMEM235,PPP3CB,VSTM2L,PRKCG,HYDIN,MASP1,BCAS3,WBP1L,CYBC1,PIGG,UHRF1BP1,PTPRB,PTPRN,FAM120C,NKAIN1,CCDC40,PLEKHB2,NWD1,ZMAT4,FIGN,UBR7,RGS3,ARHGEF10L,RNASEL,LGI2,SETD5,ARMC5,CARF,KIAA0895L,GLDN,ACER3,HSD11B1L,ATAT1,KCNIP2,ZNF331,MAPK12,ATXN2,LRRTM4,SCP2,ASIC4,FOXRED1,SCAF8,SH3BP2,FAM102A,PPP1R9A,SH3GL2,PPM1E,FNDC3A,R3HDM2,ST3GAL3,ANKRD6,ZNF365,FAM81A,SLC2A5,SMTN,LIMS2,PKNOX2,SLC6A8,SLC6A9,YPEL4,SLC8A1,SIRT2,SLC12A4,SCMH1,OGDHL,CDK5RAP2,SMARCD3,SNRPN,UNC80,MYT1L,SOX3,SOX10,SP2,IZUMO4,CAND2,TSPYL2,LHPP,TAB2,CLSTN2,CAMTA2,SMOC1,SSPO,MAPK8IP3,ZSCAN29,DIP2A,STAC2,STX1A,KANK1,NSFL1C,SYT11,PRRC2C,ZFR2,SYP,COBL,SYT5,PDLIM2,WWC1,TBX15,DMXL2,CUX2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,TNS2,CYB561A3,DICER1,CRB1,ZNF106,FAM124A,KCTD2,TNFRSF1B,PRRT1,R3HDM1,CABIN1,TPM2,WBP2,RGMB,ELP5,TRIO,TRO,TSC1,TTC3,GORASP1,OSBP2,CCDC136,RBFOX3,WIPF1,CLIP2,CLDND1,SLC13A3,XRCC4,KCNT2,ZNF142,REEP1,POLR3H,TMEM198,DPYSL5,ZNF213,MEIS3,INTS3,MAP3K12,PRTFDC1,DNALI1,STOX2,XKR7,PRDM10,LMAN2L,CIAPIN1,GAL3ST3,NAV3,PCBP4,PLD4,PARP11,RGS7BP,SMIM8,HNRNPA3,TMEM63C,NUP214,RNF170,TTC7A,PIANP,NETO1,DPF3,SLC4A10" MicroRNA hsa-miR-548b-3p:mirSVR_lowEffct hsa-miR-548b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-176 8.39E-173 1.53E-174 1.40E-173 459 1957 "RALGAPA1,KCNH8,ACADM,ASIC2,CLK4,CSMD2,FMNL2,SLC12A5,PNMA8B,ADORA3,ESYT2,BEND6,MTA3,PCDH19,OSBPL8,CC2D2A,ZNF578,UNC79,GPRASP2,SYT13,CDC42BPA,PI16,MAP4K3,PPFIA1,VAT1L,API5,USP37,MIER1,CDK10,PDXK,PDE8B,CCDC181,ATP1A2,ADAM15,BCL7A,NRP2,BLM,FUBP1,SCAPER,THSD7A,CAMK2A,CANX,SLC25A14,RUNX1T1,ZNF501,METTL6,USP2,P2RX6,AIFM1,CD38,LRBA,SEPT7,CDC42,LOC730101,LARGE1,DLGAP2,CCPG1,DIS3L,CHGA,CHM,CASC2,MS4A7,RAB33A,CLCN4,TPP1,CLTA,NGEF,TJP2,FADS2,CNR1,ARMC8,SLC25A27,SLC4A8,COX4I1,MYRIP,ZFP28,MFSD4A,FAM171B,SEC31B,CREM,CRMP1,NCOR1,CRYM,SNCAIP,ARHGEF10,SUSD5,ATRNL1,PHACTR3,CST3,DZIP3,PPP1R16B,CTH,CTNND2,NRSN1,PUM1,DCAF4,RUBCN,CX3CR1,DOCK4,GAPVD1,ARHGAP24,FRMPD4,ZNF337,LONRF1,KCTD8,DGKG,TMEM170A,C8orf34,ZBTB24,KIAA0319,DDX46,RABGAP1L,DMD,DMTF1,FAM57B,DRD1,ABI1,DRP2,DSCAM,ARRDC4,DTNA,ABCC5,DNM1L,FAM135B,EDNRB,HIPK3,CNNM1,HEYL,FSD1L,FAM13A,MBNL2,AASS,TENM1,ELAVL3,ELAVL4,EN2,EPB41L1,EPHA5,RAB9B,EPS8,EFS,DUSP27,RCSD1,RRAGB,ADGRV1,MRVI1,FAM198B,FCGR1A,ST3GAL6,FCGRT,PRMT5,TESK2,GORAB,MED12L,GTF2IRD2,KIAA1109,CAMSAP1,SUCO,IP6K2,SYNCRIP,FOXM1,SEMA4D,DCTN2,FAM49B,TPK1,ARFGAP2,DACH2,ST6GALNAC3,STAU2,KBTBD12,MSANTD4,NRG3,DKK3,MEGF10,GABRA1,GABRA2,HBS1L,ERAP1,SIGLEC8,ACSS1,KIAA1841,DNER,NEU3,PCDH17,SPIN1,GLS,MSL3,PCDH11X,GNG3,GOLGB1,GPM6A,TDRKH,FUT10,GPR12,STON1,GRIA2,GRIK1,GRIK2,PRDM5,GRM7,KIF3A,FAM19A2,ADAMTS6,FAM222A,MUM1,ATG4C,MAEL,RASSF8,IGSF21,TOX2,GPR45,FRMD3,ARHGAP36,MIER3,HMGCL,HMGCR,DHX35,HSF2,MSL1,IGF1,LRRCC1,USP54,IL6ST,IL11RA,ZNF678,INPP5B,KCND2,KCNJ3,KCNN2,LAMA2,INSYN2,FGFBP3,SMAD9,GPR155,MAP4,MARK1,LYPLAL1,MAT2A,MBNL1,TM6SF1,SHC3,SCAMP5,MITF,AFDN,MOG,ZNF680,BLOC1S2,MTTP,LYRM9,HNRNPM,NAP1L1,NASP,NEK1,NELL2,SLCO1C1,NFYA,NTRK2,NUMA1,GPR88,CHAMP1,OXTR,P2RX7,CNTN3,PCDH9,PCMT1,PCSK1,PCSK5,PDE1C,PDE4D,CDK14,NLGN3,ANLN,PIK3R1,XRN1,GPSM2,FAM216A,ST8SIA5,PURG,ING3,POU3F2,PPARA,MED1,MINDY2,PPM1B,PPP1R1A,PPP2R2B,PPP2R5E,PPP3CB,PRKACB,MAPK10,SLC26A11,DIRAS2,LRRC49,SYTL2,DEF8,GON4L,PIGG,CNTLN,OCIAD1,CASTOR1,TMEM231,RAB5B,ZNF793,ATG16L1,NWD1,ZNF493,OXR1,KHDRBS2,ZYG11B,ERI2,MORC4,GTDC1,RFX5,RGS3,RPRD1A,CCDC82,DCUN1D2,GSTCD,ROBO2,NEK11,SPIN3,ATP8B4,STK32B,NCBP3,SEMA6D,ATXN1,PRCD,SCP2,RASA3,SCAF8,NLGN4Y,ITSN1,ASAP3,MYO18A,FBXO11,NLGN1,CTXN2,DZIP1,ABLIM3,PEX26,PPP4R3A,SLC6A1,SLC8A3,SLCO1A2,TET1,SMARCC2,LIMCH1,SNAP25,KIF13A,TMCC1,MYO16,UNC80,BDP1,FNBP1,DOK5,NMNAT2,CAND2,PEG10,LMO3,SMOC1,MAPK8IP3,DIP2A,JMJD6,TACC1,KAZN,PJA1,MCF2L,DNMBP,TMEM136,ANO4,TCEA1,WSCD1,KIAA0930,SATB2,ZFP90,TRIM2,TCF12,WDR7,DOCK9,NSD1,FRYL,PMS2CL,SIRT1,DICER1-AS1,SPX,C18orf54,AP4E1,ZNF106,TIAM1,TIE1,TJP1,TLL2,TLR4,NR2E1,TMOD1,DAAM2,RIMBP2,R3HDM1,CSMD1,TPD52,TPM3,ZNF384,RGMB,NR2C2,METTL3,RUNDC3B,AMACR,TRO,TRPS1,ZMYND8,PPIL6,TST,TUB,CLHC1,TUBB1,AMOT,UBTF,GORASP1,UGT8,SLAIN1,BCL2L13,MEAF6,WIPF1,NSD2,WRN,RICTOR,XPO1,XRCC4,ZBTB14,ZIC3,ZNF19,MICU3,TRIM9,AGMO,LYPD6,TMEM198,EML6,ZNF189,SMARCAD1,CADM2,PRDM2,SLC38A1,CSDE1,XKR7,PCDH15,NAV2,PLSCR4,FZD3,DOCK8,KAT6A,SMIM8,ZNF248,VANGL2,NHSL1,PIANP,FXR1,DPF3,FAM181A,LAS1L" MicroRNA hsa-miR-181a-2*:mirSVR_lowEffct hsa-miR-181a-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.12E-176 1.19E-172 2.13E-174 1.96E-173 442 1817 "CPNE2,ASIC2,ARID1A,KLHL32,SLITRK1,ADCY6,TMCC3,RNF157,ADD1,ADD3,SLC12A5,ADRA1D,KIDINS220,ZNF608,MTUS1,HECW2,TBC1D14,KIAA1324,AK2,HFM1,CEP126,ARHGAP20,MARCH4,DOC2A,AMPH,OGT,PHF12,PPFIA1,EPB41L5,GPAM,APOC2,SHTN1,MIER1,CDK10,TMEM263,SPTBN4,CDK13,ASCL1,ASPH,NCOA1,TMEM108,CCDC181,EIF4G3,ATP2A2,ZNF583,ATP6V0A1,TTLL9,BACH1,LINC00847,KSR1,BMP7,SYNJ1,C5,RAB29,WASF1,MMD2,BTRC,CA8,CA12,CACNB2,CALB2,HAP1,CAMK2A,TRIM41,ISPD,NFS1,CLDN10,USP6,USP2,MTMR7,INA,AIFM1,CD38,LRBA,SEPT7,DCLK1,LRRFIP1,L3MBTL4,DLGAP1,TIGD7,CACNA2D2,ASIC3,SYNPR,NRXN3,NMT2,CLTC,ABCG2,CNN3,FAM149A,LETMD1,SLC4A7,COX4I1,CNRIP1,HS3ST5,SEC31B,ENTPD4,RBM39,HINFP,RGS6,DZIP3,KIAA0040,UBXN2A,USP6NL,DOCK4,GAPVD1,TBC1D5,MATR3,KIAA0586,DGKB,DGKG,SCRN1,ELMSAN1,C8orf34,ZEB2,MFAP3L,KLHL3,RHOBTB1,SACS,SPOCK3,KBTBD11,CPEB2,ACOT8,TOM1,DNAJB6,ABCC9,E2F5,SNX29,EDN1,ATL1,CNNM1,RASGRP1,KLHL5,EFNB3,FAM13A,PHF20L1,ABI2,GOLGA7,TMEM35A,C8orf37,PAN3,EMX2,VPS13B,EPHA5,EPHB1,SRRM1,DENND4A,EFS,CEP85L,ETV1,ANKMY1,KATNAL1,ADGRV1,F3,CLVS1,ABCA8,FAM198B,TBC1D16,SCML2,FCGR3A,SLC9B2,BAIAP2,CAMSAP1,FHL1,MEX3B,PCYOX1,AGAP2,FLNC,PSD2,SLC37A3,C2orf88,POMT1,STAMBP,CAMKK2,ATP6V1H,CGREF1,FYN,SDCBP2,ARPP21,ZNF234,ZNF274,SIGLEC8,ATP8A2,IGSF5,ADAM28,GHR,RNPS1,RAB30,GLS,KCNMB4,ADGRA3,GPM6A,GPM6B,GRB10,GRM7,BTN2A1,ZBTB49,SOX21,LINGO1,ADAMTS6,WIF1,ZHX1,SYNPO,ZNF491,HPCA,SHISA6,SMAP1,IDH3A,FAM95B1,GAREM2,DOCK7,SCIN,DIPK1A,METTL21A,KCNA4,KCNC2,KCNJ10,KCNK2,KIT,IPO5,STXBP5,GPR155,MAP6,MAPT,LYPLAL1,MATN2,LDLRAD3,MEIS1,MEIS2,MEST,PTOV1,SCG3,HS6ST3,MYO6,RTL5,NASP,NCAM1,NCAM2,IDNK,OTOGL,NODAL,PCBP3,SLC11A2,NTRK2,NTRK3,ODF2,SNTG1,PBX1,DPY19L2P2,PCDH8,PCDH9,PCMT1,PDGFRA,GPR85,PFKFB2,CDK14,SERPINE2,CCSER2,XRN1,FAM216A,PCDH18,HMGCLL1,PURG,RC3H2,LRP12,SCHIP1,PRRX1,EPB41L4B,CCDC144B,MAPK10,HYDIN,RELN,CNNM2,WDR25,CNTLN,UHRF1BP1,PTPRB,EML5,PTPRO,RAP1GAP,RADX,VEPH1,KHDRBS2,ZDHHC14,RDX,SLC6A15,REV3L,GTDC1,RFX4,RGS12,RIC8B,TMLHE,GSTCD,CYB561D1,ROBO1,KIRREL1,YY1AP1,ELP2,MRAP2,SNX22,NEK11,FBXW7,SPIN3,MCMBP,PRR5L,LGR4,ABCA11P,WLS,CLIP1,NCBP3,RMI1,ATXN2,SCP2,SOX6,FOXRED1,TRA2B,COPZ1,HKDC1,AMBRA1,FNDC3A,SLA,SLC1A7,KANSL3,PKNOX2,SLC8A1,SLC8A3,SLC12A2,SLC14A1,TMEM132D,CPEB4,NAXD,ZFP1,SORCS3,DMRTC1,MYH15,SMARCE1,KIF13A,CMTR2,TMCC1,USP33,SON,KIF21B,ZSWIM8,SP4,HECW1,ZNF423,ZC3H13,TSPYL2,RAP1GAP2,TAB2,CLASP2,TROVE2,POGZ,SS18,ELOVL4,NEK4,SEPT8,DIP2A,KLHL7,NECAB1,VAMP1,VPS13A,PLCB1,TMEM150C,SYN2,ATP11A,TACC1,MTCL1,PJA1,DDHD2,CAMTA1,TAL1,ADGRL3,TBX15,EHBP1,SATB2,TCF7L2,WASHC4,SZT2,WDR7,PCDHGA11,FAM189A1,ARHGEF12,HIF3A,SIK3,RNF216P1,FAM200B,DICER1-AS1,CRB1,ITGB3BP,HHIP,SLC44A1,ARL10,MTMR14,ASXL3,TLR4,ERCC6L2,RIMBP2,C5orf64,TPD52,TPD52L2,TPM1,TRIO,FNDC5,TSN,CADM1,RPL7L1,AMOT,UGT8,FLRT2,BEST1,VSNL1,LAT2,ZIC3,FMN2,SLC26A10,LYPD6,ZNF177,ZNF225,WNK1,CA10,PRDM2,CSDE1,STOX2,PRDM10,HPS4,PCDH15,URM1,SLC17A7,TMEM163,PARP11,PDSS2,HRASLS,FZD3,DOCK8,NUP214,TIGD6,VANGL2,KLHDC1,PIANP,NETO1,SENP7,JPH3" MicroRNA hsa-miR-1305:mirSVR_highEffct hsa-miR-1305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.85E-176 3.29E-172 5.77E-174 5.31E-173 448 1871 "CSMD2,ARID1A,KLHL32,GALNT13,ADD2,SLC12A5,SLC24A4,GPR158,KCTD16,HACE1,OSBPL6,CC2D2A,TAOK1,ALAD,SPOP,CEP126,ABCD2,MARCH4,PCDH10,FAM135A,LRCH2,LCORL,USP28,PPFIA1,ALS2,TNRC6C,MIER1,TMEM263,RGS20,ASPH,ZSCAN18,ZBTB10,NCOA1,NUMB,STX16,B3GALT2,NOL4,ADAM23,BACH1,SEC11C,PROM1,DST,SYNJ1,ST3GAL5,ARHGEF7,NAE1,MTMR2,JAZF1,SGCE,CA8,ZNF555,KALRN,PTBP2,CAMK2A,CANX,RUNX1T1,CLDN10,RGN,MTMR7,TMEM257,C1orf52,CDH8,LGI1,MAGI1,TIGD7,CCPG1,CHM,NDST3,SLIT2,RAB33A,CLCN4,QKI,NIPBL,ARMC8,LETMD1,SLC4A7,ABI3BP,RCHY1,AHCTF1,RTTN,ACBD5,ZFP28,CNRIP1,MFSD4A,HS3ST5,CLOCK,PREPL,CREM,HAPLN1,GDA,SUSD5,PDE4DIP,PLXNA4,ERC2,APPL1,UBXN2A,PHF14,PUM1,RIMS2,DOCK4,FGFR1OP2,FRMPD4,TOX,ZFYVE16,ZNF337,KIAA0586,PABPC5,ARMCX4,ARMCX2,SPATA2,JAKMIP2,ZNF804A,ZEB2,ZBTB24,MYEF2,CEP170,BLOC1S6,FBXO25,ZC3H11A,ALKBH8,RHOBTB1,SMG7,SACS,SPOCK3,G3BP2,KBTBD11,DLG3,CPEB2,DPP6,DRD1,PDCD6IP,DTNB,DYRK1A,DNM1L,GOLT1B,WDPCP,FAM135B,KLHL5,TMTC1,RBM12,FAM13A,MBNL2,KCTD3,TENM1,STARD3NL,EN2,LRRC17,ENPP6,ZNF549,DNAJC27,ADGRV1,F8,CLVS1,CACNG3,TAOK3,GORAB,ACTL6B,PRKAG2,SUCO,MEX3B,FOXF2,IQCG,SLC37A3,UFM1,FAM49B,CAMKK2,ATP6V1H,KHDRBS3,MSANTD4,NRG3,OGA,DKK3,GABRA2,CHL1,GABRB1,CAB39,HBS1L,ARPP21,ZNF234,NEK6,NCKAP1,SIGLEC8,C15orf41,SEPT9,GATM,ALDH1L1,TUBGCP4,ARFIP1,GHR,PPARGC1A,MALT1,COPS8,GLRB,GLS,PCDH11X,ZNF638,ZNF782,LNX1,WDFY3-AS2,EML4,ATP2B1-AS1,GRB10,GRIA1,GRIA4,NR3C1,GRM7,GRM8,BTN2A1,KIF3A,LINC01551,LINGO1,PSIP1,MAP4K5,MUM1,HAS2,PADI2,ZHX1,FRMD5,HMGCR,HNMT,HNRNPK,CFAP126,USP51,ICA1,IFI16,SOWAHA,IL6R,IL12A,ZNF678,INPP1,TUBB2B,LRRTM3,NME9,JAK1,KCNC1,CREG2,IPO5,STXBP5,CYP27C1,LIG4,HECTD2,NCOA7,MAP2,MAP4,MARK1,MBNL1,LRP1B,MEIS2,MITF,AFDN,MOBP,MXI1,MYBPC1,VWA2,NOVA1,HCN1,NTRK2,CHAMP1,PCDH9,PRTG,PLCL1,SMIM7,HMGCLL1,TRHDE,STRN3,SPATA6,FA2H,NXPH1,SH3KBP1,CCDC144B,CRLS1,PPP3CB,KANSL1,PRKACB,CEP41,PKIA,MAPK4,MAPK9,GRAMD1C,DCHS2,CNNM2,BCAS3,LRRC49,CNTLN,BDNF-AS,PTK2,PTPRO,TTC13,TMEM255A,RAD17,ATG16L1,RBBP8,KHDRBS2,MSANTD2,TRIM68,ERI2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RPRD1A,ZFHX4,ZNF532,TMLHE,PNMA8A,CCDC102B,MRAP2,RPE,ATP8B4,TCP11L1,CNTNAP3,FAM161B,MEG3,ABCA11P,ATAT1,CLIP1,ZNF331,CCDC112,TRAPPC13,AP1AR,SALL1,SEMA6D,LRRTM4,SCN7A,FNIP1,TNFRSF19,ZFP2,ITSN1,PPM1E,NTNG1,MAGI3,CHD9,ST3GAL3,FAM81A,PPP4R3A,SEPHS1,SLC12A2,TET1,SORCS3,CDK5RAP2,RCOR3,ANKRD36,RIMS1,CABCOCO1,CMTR2,SNRPN,PALLD,USP33,SON,SOX2,SOX5,UHRF1BP1L,CDK19,NPAS3,TAB2,TROVE2,CLSTN2,COLGALT2,LRRC4,NXT2,MPRIP,TTBK2,SYT11,NUDT10,SYPL1,ANKRD28,SYT4,C12orf76,TAC1,POPDC3,PJA1,DDHD2,CAMSAP2,AGTPBP1,DMXL2,SATB2,RPGRIP1L,SZT2,WDR7,PCDHB10,PCDHB9,PCDHB6,GPRIN3,PCDHA1,FRYL,RNF175,CRB1,C18orf54,ZFP91,HEY2,TMOD1,TMPO,C5orf64,TPM1,SYNPO2,RUNDC3B,TRPC3,FNDC5,TSN,RFTN2,TMEFF2,SGK3,CADM1,FAM155A,PLEKHH2,CCDC14,TBC1D15,P2RY12,LAT2,RICTOR,XPO1,PCDH20,ZIC2,ZNF32,TRIM9,ZNF540,MKRN3,LYPD6,REEP1,FSTL5,LAMP5,PLPPR5,SYNC,SLC30A4,EMSY,CADM2,PRDM2,LINC02210,STOX2,PRDM10,ADAMTS9,SCG2,PCDH15,FIP1L1,SLC17A6,PARP11,ST7,PHTF2,ADAMTSL3,JMJD1C,NLRP3,RNF170,SSPN,FRMD6,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-100*:mirSVR_lowEffct hsa-miR-100*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-175 7.59E-172 1.31E-173 1.21E-172 442 1825 "CPNE2,TTYH1,KCNH8,ACADM,ACLY,CSMD2,KLHL32,ADCY2,KLRC4,ERMN,ADORA1,ADRA1D,MTA3,PCDH19,TXNDC16,CC2D2A,ALAD,ABCD2,PCDH10,FAM135A,OGT,DPP10,EP400,USP28,PPFIA4,APBA2,APC,VAT1L,TNRC6C,LGR5,AQP4,TMEM263,CASK,ZFYVE28,ARNTL,CAPRIN2,ASPH,DDX3Y,ATP1A2,EIF4G3,ATP1B3,STX16,RNF182,NOL4,ADAM23,RGS9,NRP2,CFLAR,BTK,SGCE,IL33,CA12,CALB1,CAMK2D,VSTM2A,SPAG9,MAP7,PRC1,RGN,CD86,CD38,CDH2,CDH10,CHGB,SOCS6,CNOT8,DLGAP3,EPS15L1,NRXN3,ZFYVE9,SRP14-AS1,NIPBL,ARHGEF6,FAM149A,COL4A5,SUMF2,BTF3L4,AKAP5,SLC4A8,BAG4,ZNF521,HS3ST5,CP,CHD1L,FAM171B,C2CD2,CREM,SLC32A1,TRIM69,TENM4,ARHGEF10,MICAL2,CSNK1E,CSNK1G3,SUSD5,ATRNL1,NCAN,VAC14-AS1,APPL1,CTNND1,PUM1,PPP6R2,CX3CR1,DOCK4,KATNAL2,SNPH,TOX,ZFYVE16,IST1,DGKB,TOMM20,PITPNC1,YTHDC1,ZEB2,TIAM2,FBXL5,KIAA0319,GSDME,POM121,SV2B,RABGAP1L,FAM107B,SEC16A,DLG2,GRIN3A,DMD,HS3ST4,HS3ST2,DOCK2,CASP8AP2,ECM2,MAMLD1,DNAJB6,DNM1L,E2F5,WDPCP,EDN3,EDNRB,ATL1,RASGRP1,KLHL5,FRY,YAF2,FAM13A,PHF20L1,EGFR,KMT5B,AASS,GOLGA7,COPS4,TENM1,PAN3,USPL1,EIF1,PLEKHO1,EPHA5,KCNMB2,GPHN,SRRM1,NCALD,CDHR1,DNAJC27,RASL12,KATNAL1,F3,CEP78,KAT8,GORAB,SLC9B2,KIAA1109,PRKAG2,CAP2,FOXM1,FLT1,SGIP1,C2orf88,EFCAB2,JKAMP,FAM49B,ZNF605,CELF1,DACH2,GPR153,STAU2,NRG3,STAG2,MEGF11,GABRA1,GAD1,GAD2,GALC,RAPGEF6,NCKAP1,ERAP1,MTHFD2,DISC1,ATP8A2,TUBA8,SESN1,ADAM28,GFRA2,RAB30,LUZP2,DCLK2,GNAS,FERMT2,LNX1,ADGRA3,PRRC2B,GPM6A,GPM6B,GPR19,GRIK2,CACFD1,NR3C1,GRM8,LINC00839,FAM19A2,AP4S1,RNFT2,ZHX1,TNFAIP8L3,ELOVL5,AGBL5,HNMT,HNRNPK,HSP90AA1,SMAP1,EID2B,IGF1,ZIC5,RBPJ,PLD5,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KCNN2,KTN1,MAT2A,AQP11,MBP,SYT9,MEIS2,MIA2,PPM1L,ERICH3,MRPL42,CCDC80,ADAM22,MTR,MXI1,MYO6,NAP1L1,NCAM1,NOS1,SLC11A2,NRCAM,NTRK3,ODF2,ZDHHC22,PAK3,CNTN3,PAX6,PBX1,PCMT1,PCSK5,PDE1C,PDGFRA,ENPP2,GPR85,NALCN,FAM218A,ZFYVE21,TMEM38A,PLCL1,FTO,PURG,PMP2,STRN3,LRP12,SCHIP1,ING3,POU6F1,CRLS1,PPP2R5E,PPP3CA,KANSL1,RANBP3L,PRKACB,PKN2,GRAMD1C,BCAS3,SLC22A23,MDGA2,PLPPR1,PXK,TMEM260,STK32A,PTPN13,PTPRG,FAM120C,PID1,CEP97,CCDC40,ENOX1,KHDRBS2,ZYG11B,PBRM1,SETD5,ARMC5,MRAP2,RPE65,NEK11,FBXW7,ZC3H14,ATP8B4,RPS6KA2,EMID1,MEG3,SOX8,WLS,SALL1,SEMA6D,SATB1,CSRNP3,SCN3A,LRRTM4,SCN8A,SCP2,SLC30A10,TRIM46,CASC3,MRAS,RASA3,HSPA4L,SGK1,ITSN1,PPP1R9A,SH3GL3,CPEB3,SHC4,FNDC3A,CNKSR2,NLGN1,ANKRD6,ZNF365,SLC1A7,WDR47,FAM214B,SIRT2,SLC14A1,DMRTC1,RCOR3,LIMCH1,RIMS1,MBD5,FAM126B,UNC80,USP33,SON,PDZD2,WDTC1,ZHX3,ZSWIM8,CLUAP1,KDM4C,BEX1,SRPK2,COLGALT2,STOX1,SSTR2,ZC4H2,LRRC4,ERBIN,ZSCAN29,CEP68,AJAP1,NSFL1C,NECAB1,FGD4,PRRC2C,SYN2,SYT4,MTCL1,PJA1,CAMTA1,EXOC7,FAM208A,UNC5D,KLHL4,SIN3B,CUX2,ZEB1,SYNE1,DOCK9,RALYL,NSD1,ARHGEF12,PUM2,GPRIN3,PCDHA5,CYB561A3,RNF216P1,ITGB3BP,GPR161,HHIP,MTMR14,ACTR6,TMPO,RIMBP2,TPD52,PDSS1,STXBP4,NTSR2,SGK3,RPL7L1,AMOT,WIPF1,XPO1,ZFP37,ZBTB14,KCNT2,TRIM9,EML6,PRTFDC1,SLC38A1,TUBA1A,MDH1B,PCDH15,ITM2C,FAM47E,C12orf4,GOPC,DOCK8,UBE3B,JMJD1C,VANGL2,NHSL1,SSPN,KLHDC1" MicroRNA hsa-miR-485-3p:mirSVR_lowEffct hsa-miR-485-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.14E-175 1.20E-171 2.04E-173 1.88E-172 442 1827 "KCNH8,SYN3,CLK4,ABHD6,SYS1,CSMD3,ADD3,GRAMD1B,SLC44A5,AP1B1,GPR158,HECW2,RTL9,OSBPL1A,NME5,OSBPL8,HFM1,C1QTNF3,ALCAM,AMPD3,ZFAT,CDC42BPA,LRCH2,CNIH2,PPFIA1,PKP4,APBA2,APBB2,APC,EPB41L5,DGKD,DDO,USP37,CADPS,ASPA,MARK4,NCOA1,MTMR9,DPY19L3,ATP6V0A1,MYOM1,SNAI3-AS1,MPDZ,DCAF5,BMPR1B,CDK5R1,ST3GAL5,ARHGEF7,LINC00906,SGCE,CA8,CACNB4,CALB2,KALRN,PTBP2,CAMK2G,CANX,VSTM2A,ISPD,SPAG9,PRC1,ZNF501,CLDN10,CCK,P2RX6,CD38,C1orf52,DGKI,CD81,CDH2,CDH8,LRRFIP1,CDO1,ADGRG1,FOXN3,CHM,CHN2,SYNPR,B4GALT6,NRXN3,COG1,FBXO7,ABCG2,SULT4A1,HECTD1,MAP4K4,CNTN1,ARMC8,COL4A5,SLC4A8,TBPL1,ACBD5,ZNF521,MFSD4A,CP,RBM39,SNCAIP,CSF2RA,FEZ2,SUSD5,SIPA1L1,SOCS5,CNTNAP2,PLXNA4,ERC2,PNPLA8,CTH,CFAP61,CTNND2,NRSN1,ST18,BOC,FRMPD4,KIAA0513,ZFYVE16,KIAA0586,TMEM170A,DNAL1,DCC,ARMCX2,ELMO1,GUCD1,POM121,SNAP91,FAM107B,DLG2,RAB39B,USP3,DMTF1,DPH1,DTNA,DNAJB6,DNM1L,WDPCP,EDN3,EDNRB,PHC2,SEMA3D,TMTC1,PHF20L1,ABI2,USPL1,LRRC23,KCNMB2,SPEG,CDKL3,ETV1,DNAJC27,SIRPB1,EXTL2,CLVS1,ATP8A1,MED12L,OLFM1,FGF12,SUCO,HPCAL4,SYNCRIP,AGAP3,FOXO3,FLT1,TACC2,SORBS1,FAM49B,CAMKK2,ZNF605,KHDRBS3,DACH2,STAU2,NRG3,OGA,STAG2,DKK3,MEGF10,GABRB3,GABRG1,NEK6,MTHFD2,DISC1,INPP5K,LRRC37A6P,CPLX2,MSTN,MMADHC,GK,DBF4,SPIN1,GLRB,GLS,FERMT2,GPM6B,ATF7,TDRKH,FUT10,GPR12,GPR34,RAPGEF4,GRIK1,GRIK3,GRM7,GSN,FAM19A2,RNF165,BVES,MFSD2A,LINGO1,PSIP1,MAP4K5,MAEL,RASSF8,HAS2,C1orf94,DDX19B,ELOVL5,HNMT,IGFBPL1,HNRNPK,C5orf24,IGFBP1,ZIC5,RBPJ,LIX1,ZNF678,INSM1,JAK2,KCNJ3,KCNK1,KIF5C,IPO5,STXBP5,PAXBP1,ARHGAP12,NCOA7,MARK1,MAT2A,MBP,CHIC1,TM6SF1,LRP1B,SHC3,AFF1,XRRA1,COL28A1,BLOC1S2,HS6ST3,MYO7A,MYO9A,NAP1L1,NCAM2,NDP,NDUFA5,NEFM,NFIA,NFE2L2,NFYA,CNOT4,DNHD1,NTRK3,OMG,FAM225B,OPHN1,P2RX7,PAH,GLIPR1L2,ETFRF1,CDK18,PDE3B,PDE4B,PDE4D,ENPP2,PFKFB3,FAM98B,OLA1,SSH1,NALCN,ANLN,SCHIP1,ING3,MBOAT7,PTPA,PPP2R5E,PPP3CB,KANSL1,RANBP3L,CEP41,MAPK10,HYDIN,DCHS2,RELN,SYTL2,SIDT1,ANKHD1,BDNF-AS,ZSCAN32,ZIK1,PTPRE,FAM120C,PPP2R3C,PLEKHB2,SH3TC2,FAT4,ZCWPW1,RADX,RDX,GAL3ST4,RET,ZDHHC4,TTLL7,SLC25A36,RERGL,RORB,NEK11,ARMH4,STK32B,MEG3,SOX8,CLIP1,RTN1,SEMA6D,SATB1,ATXN2,ELMOD1,IL17RB,SOX6,SUPT20H,SGK1,SH3GL3,KIF16B,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,BCAN,NLGN1,DZIP1,NUBPL,SLA,ZNF365,FAM81A,RAB3GAP1,CCDC88A,SLC15A2,BTBD7,ATF7IP,NAXD,MAST1,IFT122,RIMS1,MYO16,SCN3B,DOP1A,SON,SOX1,SOX2,TNIK,SOX5,BDP1,KDM3A,HECW1,KDM4C,ZBTB43,NPAS3,LMO3,SRPK2,TROVE2,ITPRID2,NXT2,ELOVL4,CEP68,RGL1,KANK1,GSE1,KLHL7,ARHGEF9,NUDT10,C3orf70,PLCB1,COBL,SYT4,DDHD2,ROBO3,MCF2L,EXOC7,UNC5D,TBCEL,TMEM136,ANO4,VWA3A,TCF4,TCF7,TPCN2,RPGRIP1L,WASHC4,NAT16,PCDHB7,SIK3,ZFPM2,ITGB3BP,ARL10,ERCC6L2,CSMD1,TNS1,ZNF346,STXBP4,ANO5,SSBP2,TUB,UBE3A,SLAIN1,PITPNB,P2RY12,ZNF17,ZNF24,ZNF28,ZNF32,TRIM9,FMN2,REEP1,FSTL5,PLPPR5,UPF3A,WNK1,EMSY,MFF,LRP8,EVI5,TUBA1A,ADAMTS9,SCG2,PCDH15,FIP1L1,SLC17A6,GOPC,FZD3,RTN4,UBE3B,ZNF248,FXR1,FRMD6,IFT88,SENP7" MicroRNA hsa-miR-519c-3p:mirSVR_highEffct hsa-miR-519c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-175 1.36E-171 2.27E-173 2.09E-172 408 1555 "KCNH8,NCKAP5,ADCY6,GALNT13,KIDINS220,SLC24A4,ZNF608,GPR158,HFM1,LRRC7,SPARCL1,SRPX,ABCD2,ARHGAP20,MRTFA,OGT,LRCH2,SEMA7A,EP400,USP28,API5,SHTN1,LINC00173,STK33,CAPRIN2,ZBTB10,RASL11B,ATM,SLC4A4,ATP2A2,ATP2B1,ZNF583,B3GALT2,NOL4,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,IL33,HIP1R,MAP7,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,ZFYVE9,IGLON5,BTF3L4,SLC4A8,RCHY1,AHCTF1,HS3ST5,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,CHD5,PITPNM3,UBXN2A,PHF14,NRSN1,PPP6R2,RUBCN,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,SIRPA,MYEF2,FBXL5,PLPPR4,SACS,WDR20,DMD,USP3,CPEB2,DMTF1,DPYSL2,DNAJB6,DYRK1A,DNM1L,ABCC9,EBF1,ANKRD46,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,EML1,CALCRL,EPHA5,KCNMB2,CEP85L,RASL12,EZH1,F3,ACSL4,TAOK3,CEP78,TESK2,SLC9B2,FGF13,FGF14,PRKAG2,MEX3B,FOXG1,CAP2,FOXF2,RGPD5,JKAMP,NBEA,UFM1,TPK1,ATP2C1,NSG1,GAB1,GABBR1,GABRA1,GAD2,B4GALNT1,ARPP21,ERAP1,DISC1,MYOZ2,SULT1C4,ZNF276,COPS8,GLYR1,GLS,TOX3,ZNF638,LUZP2,GNAL,RAPGEF4,GRB10,GRIA4,ADAMTS8,PRDM5,GRM5,GRM7,CIT,LINC00839,RNF165,RABL2A,PSIP1,ADAMTS6,GUCY1B1,HAS2,HPS5,NXPH2,FRMD3,MIER3,HNMT,TLX1,IRF8,DOCK7,LRRCC1,ZNF678,DIPK1A,JAK1,KCND2,KCNJ10,KCNK1,KCNN2,CREG2,KIF5A,KIF5C,LIG4,FGFBP3,ARHGAP12,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,MDM4,LRP1B,MID1,MITF,XRRA1,MOG,ERICH3,BCO1,MSR1,RSPO2,LAYN,MYT1,NACA,NELL1,NELL2,NEUROD1,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,NTRK2,OCRL,P2RY1,GPR137C,CNTN3,PDE3B,PDGFRA,ENPP2,GNG2,BEST3,CCSER2,TMEM38A,JAKMIP1,SCHIP1,PMS2,EPB41L4B,SH3KBP1,PPM1B,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PKIA,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTHLH,PTPRB,ACSM5,ZSCAN2,QDPR,RAB5B,PID1,CEP97,SLC25A48,USP47,RAD17,ATG16L1,ARID4A,RBBP6,ZDHHC14,SLC6A15,ZYG11B,RET,RFX3,RFX5,SLC25A36,ZFHX4,CCDC82,SETD5,RAVER2,PNMA8A,ROBO1,RORB,UEVLD,ZNF671,LRRK2,CNTNAP3,RTN1,RYR3,SALL1,CSRNP3,HOGA1,SCN3A,FAM19A1,LINC00461,PRCD,SCP2,HSPA4L,ITSN1,PPP1R9A,ARX,KIF16B,CPEB3,SHC4,CHD9,SLITRK3,SYBU,PAAF1,SLA,FAM81A,RUFY2,KANSL3,LRRC55,CCDC88A,BTBD7,NAXD,RCOR3,ANKRD36,KIF13A,SNRPN,TMCC1,KDM4B,MYT1L,TRERF1,SOX5,DOK5,HECW1,TEX2,IQSEC2,SPART,C11orf87,PBLD,CLASP2,TROVE2,POGZ,SMOC1,LARP4,ERBIN,ADHFE1,GANAB,NECAB1,PLCB1,SYT1,SYT4,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,RALYL,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,TGFBR3,AKTIP,SLC44A1,THRA,TLR4,HEY2,R3HDM1,KAT6B,STXBP4,TRPC1,TSC1,UBC,FAM155A,UBE3A,SLAIN1,PITPNB,FLRT2,VLDLR,TBC1D15,LAT2,NSD2,XPO1,PCDH20,ZBTB14,ZNF711,MICU3,ZNF74,MKRN3,TCEAL7,CELF4,REEP1,FSTL5,ANKS1B,CA10,MAP3K12,MFF,CSDE1,CAB39L,FAM47E,WNK3,SLC17A6,MVB12B,PLSCR4,RGS7BP,SMIM8,HNRNPA3,PHTF2,CASC15,SSPN,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-218-5p:TargetScan hsa-miR-218-5p TargetScan 3.45E-175 1.94E-171 3.17E-173 2.92E-172 295 779 "DPF1,ASIC1,ACTN1,CSMD3,ELFN2,GALNT13,PTCHD1,AP2A1,KLHL13,CASKIN1,KCTD16,LRRC7,ABCD2,MARCH4,KCNT1,PDZD4,CDC42BPA,ANK1,LCORL,PKP4,GPAM,CASK,ARHGAP5,ARRB1,RGS20,PDE8B,NUMB,INSYN2B,DPY19L3,DST,FUBP1,CACNA1I,CACNA1G,BSN,LDLRAD4,CACNB4,DIRAS1,CALM1,RUNX1T1,KRIT1,REPS2,CDH2,LRRFIP1,L3MBTL4,CDR1,NUMBL,FOXN3,CHM,NRXN3,CLCN3,NRXN1,NMT2,FHL5,CNTN1,FAM171B,HAPLN1,ANKRD44,LRIG1,NCAN,RIMS4,CNTNAP2,PLXNA4,KIAA0040,ERC2,PLCXD3,CTNND2,PUM1,CCDC144A,ARHGAP32,GAPVD1,FRMPD4,RASSF2,RIMS3,AIF1L,DNAL1,DBN1,ELMSAN1,JAKMIP2,ELMO1,HP1BP3,MAGI2,RHOBTB1,RABGAP1L,DLG2,HS3ST2,CALN1,NR1D2,CPEB2,DPP6,GOLT1B,EBF1,FAM13A,MBNL2,ABI2,PLXNC1,GOLGA7,RGS17,PAN3,EPB41L1,EPHA5,ANKRD13B,EPS8,ERBB4,CEP85L,RTN3,DNAJC27,MRVI1,CLVS1,NSRP1,KAT8,MED12L,FGF12,FLNC,PSD2,C2orf88,NBEA,CAMKK2,CELF1,GPR153,FUT9,B3GAT1,MPP6,NEURL4,DKK3,CHL1,GABRB3,BRPF3,SALL3,GFRA1,PCDH17,PPARGC1A,KIRREL3,LYVE1,RAB30,GNAO1,GNAS,GNG3,GNG4,PCLO,RAPGEF4,GRIA2,RFFL,GRIK2,GRIK3,GRM1,GRM3,PTPRT,RNF165,BVES,GUCY1A2,GPR45,KLF12,MIER3,HLF,ELOVL5,HMGB1,CELF5,IDH3A,RBPJ,DOCK7,PLD5,SCRT2,METTL21A,KCNA1,KCNB1,KCNC2,KCND1,KCND2,KCNH1,KLHL23,KCNK2,KCNN3,KCNQ3,KIF2A,KIT,LAMP2,INSYN2,LIFR,HECTD2,NAT8L,MARK1,MBNL1,LRP1B,MEF2C,SCAMP5,MITF,AFF1,JAKMIP3,MDGA1,HS6ST3,NFIA,NFIX,GPR137C,PAK3,PCDH8,PCDH9,PDE3A,PDGFRA,PDYN,GPR85,PIK3C2A,PIK3R1,FAT3,POU3F2,MED1,PPP2R2C,KANSL1,DIRAS2,PROX1,RELN,CNNM2,MDGA2,PTPRG,CEP97,RAD52,RAP1GAP,RAP1GDS1,RET,FIGN,RFX3,KLHL11,RNF220,EXD2,KLHDC8A,ROBO1,ROBO2,RORB,PCMTD2,ATP8B4,LGR4,KCNIP3,ATXN1,ATXN2,SCN2B,SCN8A,SEC14L1,ITSN1,FHOD3,ABLIM3,FAM81A,LRRC55,CCDC88A,COA1,RIMS1,MBD5,KIF13A,MYO16,MYT1L,KIF21B,BDP1,LMO3,C11orf87,CLASP2,NXT2,MAPK8IP3,MPRIP,AJAP1,NECAB1,FGD4,NUDT10,C3orf70,ACSL6,SATB2,DOCK9,PSD3,ARHGEF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,GPR161,CBX5,ASXL3,RIMBP2,FLRT2,RICTOR,KCNK12,NDRG4,ANKS1B,CADM2,GDPD5,RNF103,NAV3,CAB39L,ITM2C,MVB12B,HNRNPA3,FRMD6,DPF3,GAN" MicroRNA hsa-miR-633:mirSVR_lowEffct hsa-miR-633:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.02E-175 2.26E-171 3.64E-173 3.36E-172 443 1838 "CLK4,NCKAP5,ACTN1,XKR4,SLC25A25,CSMD3,FMNL2,ADARB2,GALNT16,SLITRK1,CCDC85A,ADCY8,TMCC3,AXIN2,CDC7,PLEKHH1,ADRB2,KIDINS220,SLC44A5,ZNF608,HACE1,KIAA1324,TXNDC16,ZNF578,ALAD,SPOP,PCDH10,FAM135A,ZFAT,MAP4K3,PPFIA1,PKP4,CACHD1,TNRC6C,AQP4,MIER1,TMEFF1,MARCH3,CAPRIN2,BRINP2,ASTN1,TMEM108,ATM,ATP1A1,CCDC181,RNF182,MTMR9,ATP6V1G2,SEC11C,NRP2,BLM,SCAPER,SGCE,NIPA1,OSGIN2,IL33,BTRC,CACNA1A,CACNA1D,CABP7,KALRN,PTBP2,CANX,ISPD,CLDN10,CCK,METTL6,ENTPD6,REPS2,CDC27,DCLK1,MAGI1,CHGB,SOCS6,ZBED5,CNOT8,PLAA,NMT2,TMEM155,CNTN1,ARMC8,LETMD1,SLC4A7,NRG2,MFSD4A,CLOCK,ANKRD44,ARHGEF10,OSBPL3,SUSD5,ATRNL1,IPCEF1,VCAN,VAC14-AS1,FAM169A,DZIP3,GREB1,PUM1,NOS1AP,BOC,DOCK4,HDAC9,ARHGAP32,KCTD8,MAML1,DAPK1,GIT2,DNAL1,ARMCX2,ZEB2,MAGI2,GSDME,G3BP2,MTX3,KBTBD11,DMD,DYNC1I1,DNM2,CASP8AP2,ABI1,ECM2,FAM78B,DNM1L,GOLT1B,EDIL3,WDPCP,EDNRB,HIPK3,TMTC1,RBM12,SH3GLB1,APH1A,ABI2,KCTD3,EIF4G2,EIF5,TENM1,BSCL2,TMEM35A,CALCRL,RRAGB,ADGRV1,ABCA8,SCML2,EFEMP1,ZSCAN30,SEC24B,MED12L,GTF2IRD2,FGF1,POLR1B,FGF11,FGF13,FGF14,AMOTL2,CAP2,IP6K2,RGPD5,ATP13A4,SGIP1,C2orf88,EFCAB2,APOPT1,UFM1,PDLIM5,STAU2,SARAF,PHYHIPL,DKK3,MEGF10,GAB1,GABRB1,HBS1L,ARPP21,MTHFD2,GART,LRRC37A6P,FAXC,MSTN,CYP46A1,MMADHC,GLS,KDM2B,ZNF782,WDFY3-AS2,GPD2,GPM6A,PRLHR,GRID1,KIF3A,BVES,MFSD2A,LINGO1,GUCY1A1,IGSF21,FRMD3,ATXN2L,HSF2,SMAP1,HTR2A,LINC00667,SOWAHA,TJAP1,IGSF1,IL12A,RIPPLY2,INPP5B,ITGAV,SLC35G1,KCNC2,KCNK1,KCNK2,KCNMA1,CYP27C1,LMO2,SYTL4,HECTD2,NCOA7,SMAD1,GPR155,MARK1,LYPLAL1,CHIC1,LDLRAD3,TM6SF1,MEF2C,MEIS1,MEIS2,KITLG,MMP16,ZNF680,JAKMIP3,NRBP2,CTNNA3,MTR,MXI1,MYO5A,MYO6,RTL5,NEXMIF,NAP1L2,NCAM2,NEUROD2,OTOGL,ALDH1L2,SLC11A2,NUMA1,OCRL,KCNK10,DPY19L2P2,ETFRF1,PCDH9,PDE1A,ENPP2,NOMO2,ZNF655,FAM218A,ZFYVE21,XRN1,PLCB2,HMGCLL1,CDIP1,SCHIP1,PRRX1,ING3,TNPO2,PPM1B,CCDC144B,PPP2R5E,PPP3CA,PPP3CB,PKIA,HYDIN,MASP1,SYTL2,MDGA2,QRICH1,NCR3LG1,PTHLH,PTK2,PTN,ZSCAN32,OCIAD1,PTPRD,PTPRG,PTPRO,FAM120C,TTC13,TUG1,RAD17,FAM184A,OXR1,RBBP6,RADX,KHDRBS2,MSANTD2,RDX,ZMAT4,REV3L,UBR7,RGS12,RNASEL,RPRD1A,ALG9,GSTCD,TMEM206,RPE,TMEM100,ARMH4,ATP8B4,ADAL,LRRK2,KCNIP1,CCDC112,ATXN1,ATXN2,ATXN7,SCN3A,FNIP1,SMPD3,SOX6,ITSN1,CPEB3,DOCK10,SHC4,MAGI3,FNDC3A,SLITRK3,BCAN,NUBPL,PPP4R3A,SLC6A11,ARHGEF40,NAPB,SLCO1A2,ZFP1,COA1,ANKRD36,RIMS1,SNAP25,KIF13A,CABCOCO1,SNRPN,PDZRN3,MYO16,RBM34,DOP1A,TRERF1,KDM4C,PEG10,ZNF423,KIF1B,CDK19,NFASC,C11orf87,ZNF621,TROVE2,EPB41L3,ERBIN,NXT2,DIP2A,GSE1,KLHL7,FGD4,ANKRD12,MTCL1,EXOC7,ADGRL3,IQCE,TCF4,SATB2,ZFP90,ZEB1,TRIM2,TCF12,PUM2,FRYL,TEK,TF,FAM200B,DICER1,SIRT1,C18orf54,AP4E1,TGFBR3,ZNF106,AKTIP,TJP1,ACTR6,TMOD1,RIMBP2,C5orf64,TRIO,TRO,TRPS1,TSN,ANO5,TTTY15,RFTN2,CADM1,UGT8,DNAJC12,SLAIN1,PITPNB,ZNF709,VGF,VLDLR,WIPF1,WRN,RICTOR,GUSBP1,ETNPPL,XRCC4,ZIC3,ZNF24,KCNT2,AGMO,CELF4,ZBTB38,TMEM237,ZNF189,ANKS1B,ZNF195,PLPPR5,ZFAND5,SYNC,SLC30A4,DNALI1,FIP1L1,FAM47E,FAM13C,AMN1,ST7,RTN4,PAK5,KAT6A,PHTF2,FBXO36,NUP214,ZNF248,RNF146,CPNE4,FAM198A" MicroRNA hsa-miR-216b:mirSVR_lowEffct hsa-miR-216b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.70E-175 3.20E-171 5.08E-173 4.68E-172 441 1823 "RALGAPA1,SERPINA3,SDE2,KCNH8,NBAT1,METAP1D,ARID1A,XKR4,ADD1,AXIN2,SORCS1,GRAMD1B,SNX30,ADRB2,DPY19L2P4,NLGN4X,SLC24A4,AP2A2,AP1B1,INTS2,MTUS1,WDR35,OSBPL8,ALCAM,UNC79,PDZD4,AMPH,CDC42BPA,LCORL,KCNAB2,UPRT,GPAM,AMER3,PPFIA3,USP37,SHTN1,TMEM263,CASK,TMEFF1,RGS20,STK33,CAPRIN2,ZSCAN18,NCOA1,DDX3Y,ATP1B3,STX16,ATP2A2,ATP6V0A1,RIPK1,BACH1,ADGRB3,BID,CFLAR,PROM1,BMPR1B,LINC00906,OSGIN2,RAB29,IL33,CACNA1D,DIRAS1,PTBP2,VSTM2A,HIP1R,KRIT1,METTL6,SYNGR3,SEPT7,ZBED1,MAGI1,IGFN1,GPR37L1,SOCS6,CHN2,RAB33A,NRXN3,FBXO7,FAM19A5,MAP4K4,CNGA3,TMEM155,FHL5,CNR1,PCYT1B,ARMC8,COL9A1,AKAP5,ABI3BP,MYRIP,ZNF521,CHD1L,SLC35F1,CLOCK,C2CD2,HAPLN1,ANKRD44,GDA,TRIM69,CS,FEZ2,ATRNL1,CHD5,APPL1,CTH,USP6NL,NOS1AP,HDAC9,GPRASP1,ARHGAP32,KATNAL2,GAPVD1,TCAF1,DCAF8,TOX,ZFYVE16,EARS2,ZNF337,TM9SF4,RIMS3,KIAA0586,KCTD8,DGKB,TOMM20,SPOCK2,BRINP1,SPATA2,YTHDC1,ZEB2,ZBTB24,ELMO1,HP1BP3,CEP170,MAGI2,ZC3H11A,GUCD1,DLX1,GRIN3A,NR1D2,SLC12A6,ABI1,DTNA,ABCC5,ABCC9,GOLT1B,AASDH,EDN1,FAM135B,FSD1L,FAM13A,MRO,KMT5B,EGR3,EIF4G2,COPS4,TENM1,C8orf37,PAN3,EIF1,EMX2,OLIG2,EPB41,LRRC17,RABEPK,SRRM1,SPEG,MRPL10,KATNAL1,NRN1,ARMCX1,ZIC4,FCGRT,FGF1,FGFR1,MEX3B,SYNCRIP,SEMA4D,FLT1,ANKFY1,EFCAB2,TRMO,SORBS1,ZNF605,ERGIC3,DACH2,STAU2,MEGF11,MEGF10,GABRA1,GABRA5,GABRB3,DENND2A,HBS1L,GALR1,ZNF234,ZNF274,NCKAP1,C15orf41,DISC1,NFU1,GHR,COPS8,GLYR1,GLS,MSL3,PCDH11X,KDM2B,PSRC1,LILRA1,PRLHR,GPR12,EML4,ATP2B1-AS1,GRIA1,GRIA2,GRIA4,GRM1,GRM7,BTN2A1,LINC00839,RNFT2,NXPH2,HMGB1,SYNPO,HNF4G,ZDHHC15,DHX35,CELF5,SMAP1,HTR2A,SCIN,IBA57,ZNF385B,ITPKB,KCNC2,KCNJ16,KCNK1,KCNK2,KCNN2,KIT,HECTD2,FGFBP3,MAP2,MAP6,MEIS1,SRSF12,MID1,POC1B,AFF1,ERICH3,ZNF680,STK32C,NRBP2,MTTP,MXI1,LYRM9,MYO9A,NEXMIF,BEX5,HNRNPM,P2RY13,NCAM1,NEUROD1,NFIA,NFE2L2,ALDH1L2,NFYA,NPTX2,NTRK2,GPR88,OPCML,LOC100128398,ZNF713,P2RX7,GPR137C,PCDH9,PCMT1,PDE3B,PDE4B,PDE1B,PENK,BEST3,PFKFB3,OLA1,TMIE,CCSER2,XRN1,KCTD15,PLIN1,MTRF1L,PURG,LRP12,ING3,RETREG2,SH3KBP1,FSD1,DRAM2,TATDN3,PPP2R2B,PPP2R5E,PRKAB2,RASGEF1B,MAPK4,PRPSAP2,CNNM2,MDGA2,PTHLH,TMEM260,PTX3,TUG1,ZNF493,KHDRBS2,ZYG11B,RET,ERI2,FIGN,RGS10,RGS12,GSTCD,RORB,ELP2,EPHA10,FBXW7,ATP8B4,SGSM1,ABCA11P,ST6GALNAC6,SALL1,HOGA1,SCN7A,SCN8A,PRCD,SCP2,SLC30A10,MRAS,NLGN4Y,FAM102A,PPP1R9A,SH3GL3,NTNG1,MAGI3,SLITRK3,ABLIM3,PREX2,RAB3GAP1,SLC12A2,NAPB,SLCO1A2,LGI3,CPEB4,SMARCE1,RIMS1,UNC80,DOP1A,TRERF1,BDP1,SOX11,KDM3A,SP4,PEG10,KIF1B,IQSEC2,RBM26,ZNF621,ITPRID2,STOX1,ZC4H2,NKAIN2,ERBIN,CEP68,RGL1,KANK1,SULF2,VAMP1,COBL,TAC1,POPDC3,TACR1,ANKRD12,CAMTA1,CAMSAP2,FAM208A,UNC5D,ADGRL3,AGTPBP1,TBCEL,KLHL4,TCF4,DMXL2,CUX2,TRIM2,GPRIN3,RNF175,CRB1,AP4E1,ZMAT3,THBS4,SLC44A1,TIAM1,ZFP91,TPM4,SYNPO2,PDSS1,RUNDC3B,DCBLD1,TMEFF2,CADM1,UBE3A,FAM181B,BCL2L13,LAT2,SLC13A3,XRCC4,ZNF24,ZNF70,CRB2,ZBTB38,DPYSL5,ANKS1B,SPIRE1,MEIS3,CIAPIN1,PCDH15,SLC17A7,KCNAB1,SLC17A6,HRASLS,FZD3,DOCK8,ST7,MARCH8,RTN4,UBE3B,SMIM8,NUP214,CERS6,TTC7A,SSPN,NETO1,CBLN2,LAS1L" MicroRNA hsa-miR-30d:mirSVR_highEffct hsa-miR-30d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.09E-174 2.30E-170 3.59E-172 3.31E-171 434 1774 "RALGAPA1,CLK4,ABHD6,ARID1A,CSMD3,GALNT16,GALNT13,RNF157,ADD1,BRAP,CDC7,SORCS1,ERMN,KIAA1211,LRFN2,ADRB2,AP2A1,AP1B1,ZNF608,INTS2,KCTD16,HACE1,TAOK1,ABCD2,MARCH4,PCDH10,FAM135A,PITPNM2,LRCH2,UPRT,ALS2,CACHD1,VAT1L,USP37,PPP4R4,TMEM263,TMEFF1,ZFYVE28,CADPS,STX16,ATP2B1,ATP2B2,DPY19L3,ADGRB3,SEC11C,BCL2L2,NRP2,BID,KSR1,DST,CACNB2,CALB2,CABP7,CAMK2D,SLC25A14,CARS,CBS,SLC5A11,USP2,SYNGR3,DGKI,SEPT7,ZBED1,LGI1,L3MBTL4,LARGE1,MAGI1,DLGAP1,CFL2,CHN1,MS4A7,NDST3,KMT2C,NRXN3,FAM189A2,QKI,MAP4K4,NIPBL,ARHGEF6,AKAP6,COL9A3,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,ZFP28,SLC35F1,PNKD,CLOCK,SLC32A1,GDA,OSBPL3,CSNK1G3,PDE4DIP,GREB1,CTNND2,CCDC144A,DOCK4,HDAC9,GAPVD1,HDAC4,TOX,TBC1D5,MATR3,KCTD8,MAML1,TOMM20,YTHDC1,JAKMIP2,C8orf34,CEP170,MAGI2,BLOC1S6,ALKBH8,PLPPR4,SACS,SPOCK3,RABGAP1L,WDR20,RAB39B,DMD,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,RCAN1,MAMLD1,DYRK1A,DNM1L,ABCC9,GOLT1B,EDIL3,WDPCP,YAF2,CELSR3,FAM13A,SUGP2,MBNL2,TENM1,TMEM35A,EML1,DCTN4,EN2,EPB41,EPB41L2,LRRC17,KCNMB2,STX2,DENND4A,CDHR1,RCSD1,EXTL2,ABCA8,SH3YL1,SCML2,ATP8A1,GORAB,AMOTL2,SCARA3,MEX3B,FOXG1,CAP2,SYNCRIP,RGPD5,SORBS1,UFM1,FAM49B,ATP6V1H,KHDRBS3,DACH2,NSG1,MSANTD4,NRG3,OGA,ZMAT1,STAG2,GABRA5,CHL1,GABRB1,TRAF3IP2,HBS1L,JPH4,GALR1,IP6K3,ERAP1,ATP8A2,KIAA1841,MYOZ2,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLRB,GLS,TNRC6A,GNAO1,GNAS,ADGRA3,PRUNE2,GPM6A,TDRKH,GPR19,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,GRM1,GRM3,GRM5,CIT,FAM19A2,GUCY1B1,CELF3,ARHGAP36,MIER3,HLF,ELOVL5,ZNF491,SMAP1,RAB41,SOWAHA,DOCK7,ZNF678,DIPK1A,LRRTM3,LRRTM1,JAK1,JAK2,KCNA2,KCNJ3,STXBP5,CAMK2N2,LIMS1,PAXBP1,HECTD2,MAP6,MARK1,LYPLAL1,MAT2A,SYT9,CHIC1,MEIS2,MID1,PPM1L,ERICH3,MRPL42,JAKMIP3,ADAM22,PABPC1L2A,NAP1L2,NAP1L3,NEFM,NEK1,NF1,SMIM11A,NTRK3,NUCB2,OCRL,OMG,PCDH9,PDE4D,PIRT,PIK3CD,SNX10,MAPKAP1,EPB41L4B,PPM1B,PPP2R5E,PRKACB,EPDR1,SLC26A11,VPS13C,LAMA1,ANKHD1,ELOVL2,PXK,TMEM260,PTPN13,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,ERI2,FIGN,RGS7,TTLL7,RNF220,RPRD1A,SETD5,EXD2,RAVER2,CARF,ROBO2,PCMTD2,LRRK2,ABCA11P,TRAPPC13,AP1AR,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,LINC00461,SLC30A10,SUPT20H,SCG5,ITSN1,FRMPD1,ARX,KIF16B,CPEB3,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,FHOD3,NLGN1,PAAF1,FAM81A,KANSL3,PKNOX2,SLC6A9,SPHKAP,TET1,ZFP1,SORCS3,SMARCE1,RCOR3,TTC17,LIMCH1,SNRPN,TMCC1,MYO16,SON,BDP1,DOK5,KDM3A,SP4,HECW1,BEX1,KIF1B,NPAS3,SPART,CLASP2,SSTR2,NKAIN2,STAU1,ZSCAN29,NEK4,RGL1,STXBP1,SYPL1,COBL,DDHD2,CAMTA1,MCF2L,ADGRL3,ANO4,DMXL2,SATB2,USP22,CLASP1,WDR7,SYNE1,USP32P1,SLC35G2,SIRT1,TMEM121,CRB1,SLC44A1,GZF1,TLL2,R3HDM1,CSMD1,TP53BP2,C9orf85,METTL3,PDSS1,RUNDC3B,NEIL2,TRO,ZMYND8,DCBLD1,ANKRD20A2,SSBP2,RFTN2,PITPNB,CCDC14,MICAL1,WIPF1,CLDND1,XPO1,PCDH20,ZIC1,ZNF711,MICU3,MKRN3,CELF4,ZBTB38,SPIRE1,LAMP5,ZFAND5,CA10,SLC30A4,MAP3K12,CSDE1,STOX2,RNF103,ADAMTS9,HPS4,FIP1L1,PARP11,FZD3,DOCK8,MARCH8,PAK5,HNRNPA3,PHTF2,CERS6,FAM219B,NLRP3,FRMD6,RNF146,GAN" MicroRNA hsa-miR-217:mirSVR_lowEffct hsa-miR-217:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.72E-174 2.65E-170 4.08E-172 3.76E-171 436 1791 "KCNH8,EMILIN3,CSMD2,ARID1A,KLHL32,ADD1,PNMA8B,SORCS1,KIAA1211,RNF150,PTCHD1,BEND6,AP2A2,ZNF608,GPR158,NR0B1,KIAA1324,TAOK1,SEMA6A,CEP126,UNC79,KCNT1,AMPD2,ZFAT,CCDC146,MYH7B,USP28,SUGT1P4-STRA6LP-CCDC180,VAT1L,API5,USP37,SHTN1,CPNE5,LINC00173,CDK13,NUMB,SLC4A4,EIF4G3,ATP1B3,ATP2B1,DPY19L3,ADAM15,BACH1,LINC00847,MPDZ,PROM1,CDK5R1,FUBP1,SCAPER,NIPA1,CACNB4,CALB2,PTBP2,CAMK2D,CANX,ISPD,KRIT1,SYNGR3,NEURL1,C1orf52,DCLK1,LGI1,CFL2,NPIPA1,CHRNA4,KMT2C,KIAA1549L,CLTA,QKI,SULT4A1,MAP4K4,CNN3,ARHGEF6,CNR1,AKAP7,IQCK,COL4A5,SLC4A7,BAG4,ACBD5,ZNF521,PNKD,SEC31B,CLOCK,C2CD2,CREB5,NCOR1,GDA,TRIM69,CSF1,TENM4,CSF2RA,SEC24C,CSNK1G3,VCAN,FAM169A,PPP1R16B,APPL1,PNPLA8,CTNND1,RIMS2,SEC14L5,BOC,KATNAL2,RIPOR2,TOX,LIN54,SPOCK2,ARMCX4,SPATA2,YTHDC1,ZBTB24,TIAM2,PLPPR4,DLG2,EXOG,GRIN3A,USP3,CDON,PDCD6IP,ARRDC4,FAM78B,WDPCP,SGK2,TMTC1,SH3GLB1,CELSR3,MRO,KMT5B,EIF5,IRAK4,TENM1,ELAVL2,ELN,TMEM35A,CALCRL,PAN3,DCTN4,EMX2,EN2,EPHA5,EPHB1,KCNMB2,RABEPK,MRPL10,ANKMY1,SIRPB1,KATNAL1,F5,CLVS1,FAM198B,WAC,RPS6KC1,ATP8A1,FCGR3A,FECH,FER,GTF2IRD2,FGF1,FGF12,POLK,SUCO,UBE2E3,FOXG1,SEC23B,SYNCRIP,FLT1,NELFCD,POMT1,APOPT1,PDLIM5,TRIM16,NPTN,ST6GALNAC3,STAU2,NRG3,ZMAT1,STAG2,MEGF10,GABRA5,HBS1L,B4GALNT1,JPH4,RAPGEF6,SALL3,IP6K3,ZNF559,DISC1,LRRC37A6P,ALDH1L1,MSTN,ARFIP1,PCDH17,LYVE1,GK,TOX3,PCDH11X,AIFM3,KDM2B,HTATSF1,PRRC2B,GPD1,GPD2,ATF7,TDRKH,GRIN1,CACFD1,GRM2,GRM7,GRM8,RNF165,ZBTB49,PSIP1,GUCY1A1,GUCY1B1,NXPH2,FRMD5,ARHGAP19,BACH2,OPALIN,AGFG1,SHISA6,HSP90AA1,ATCAY,ZNF546,RBPJ,KNDC1,TJAP1,SCIN,INPP1,ZNF385B,LRRTM3,METTL21A,KCNA4,KCNK2,KCNN2,CREG2,KLRC3,IPO5,PAXBP1,ARHGAP12,GPR155,AQP11,MATN2,MBNL1,MEF2C,MEIS1,KCTD6,MMP16,MN1,WDR49,DDX25,MXI1,RTL5,ZNF862,NAP1L1,NCAM1,ZC3H12B,NFIA,NNAT,CNOT4,OCRL,OPCML,OPHN1,GLIPR1L2,PAK3,PCSK5,PDE3B,ENPP2,PFKFB2,PIK3C2A,ZNF655,FAM218A,CCSER2,FTO,HMGCLL1,LRP12,ING3,SEPT4,FAT3,POLG,POU3F2,PPARA,CRLS1,PRKAB2,EPDR1,GRAMD1C,HYDIN,CYBC1,LRRC49,APTX,CNTLN,ANKHD1,NCR3LG1,SPDL1,PTPRD,PTPRN2,PTPRZ1,ACSM5,CEP97,USP47,PLEKHB2,RAD51D,FAM66C,ZYG11B,TRIM68,RET,RFX4,SLC25A36,RIC8B,ZNF532,ROBO1,ELP2,ZC3H14,GLDN,STK32B,LGR4,RYR3,SALL1,HOGA1,SCN2A,SCN4B,PRCD,PEAR1,SEC14L1,SCAF8,NLGN4Y,ITSN1,PPM1E,FERMT1,CHD9,NLGN1,NUBPL,ABLIM3,SLC2A5,SLC12A2,SPHKAP,SMARCA4,SMARCE1,SNAP25,SNCA,MBD5,PALLD,UNC80,USP33,FAM219A,TRERF1,BDP1,KDM3A,ZSWIM8,ENKUR,MYCBP2,CDK19,TSPYL2,C11orf87,TAB2,EPB41L3,LARP4,NKAIN2,ELOVL4,RGL1,ADHFE1,STX1A,SEPT3,FGD4,SYN2,SYT1,ANKRD28,POPDC3,TACC1,TACR1,PJA1,CAMTA1,MCF2L,TAF9,FAM208A,KIAA1107,SMG6,MGRN1,ANO4,ACSL6,VWC2,DMXL2,TCF7,TCF7L2,TPCN2,CLASP1,DOCK9,RALYL,FRYL,SIK3,TEK,ITGB3BP,AKTIP,ARL10,TLL2,ERCC6L2,TMPO,R3HDM1,TPD52,TPM2,C9orf85,ANO5,TTC3,UCHL1,UGT8,DNAJC12,PITPNB,BCL2L13,TBC1D15,NSD2,CLDND1,GUSBP1,SLC13A3,ZNF24,GPR158-AS1,LYPD6,FSTL5,EML6,MAP3K12,ZXDA,PRDM2,RNF103,TRIM16L,MVB12B,UBE3B,PHTF2,CASC15,CERS6,TIGD6,SSPN,KLHDC1,FRMD6,SOCS4,ST8SIA2,SLC4A10" MicroRNA hsa-miR-16-1*:mirSVR_lowEffct hsa-miR-16-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.57E-174 4.25E-170 6.44E-172 5.93E-171 456 1960 "CLK4,CSMD3,KLHL32,KLRC4,AXIN2,INTS2,PCDH19,HACE1,OSBPL1A,CC2D2A,C1QTNF3,LRRC7,ALAD,SEMA6A,CEP126,BCAR3,GPRASP2,ZNF687,ANK3,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,DDO,PPP4R4,CASK,SPTBN4,ARHGAP5,NCOA1,CCDC181,NOL4,DPY19L3,TTLL9,BACH1,ADGRB3,DCAF5,NRP2,DST,SYNJ1,FUBP1,BTK,AP1M1,GYG2,C5,RAB29,WASF1,LDLRAD4,CACNB4,CALB1,CAST,MAP7,CBS,CCNH,AIFM1,CDH2,ZMYM4,MAGI1,TIGD7,CCPG1,RCBTB2,SRSF11,CHN2,CASC2,RAB3C,CNOT8,KMT2C,KIAA1549L,COG1,NMT2,C4orf33,AKAP7,COL4A5,SLC25A27,ACBD5,MYRIP,ZFP28,NRG2,MFSD4A,RBM39,CREB5,HAPLN1,ANKRD44,GDA,TENM4,LRRC3B,MICAL2,OSBPL3,VCAN,NCAN,SOCS5,APPL1,PUM1,RIMS2,ZSCAN23,CYBB,BOC,DOCK4,GAPVD1,RIPOR2,TOX,ZFYVE16,LONRF1,KCTD8,DGKB,DAPK3,PITPNC1,YTHDC1,C8orf34,MYEF2,KIAA0319,KLHL3,SNAP91,SPOCK3,AK5,WDR20,FAM107B,SEC16A,CHRDL1,DNM1,CDON,DOCK2,DPYSL2,ARRDC4,DUSP9,E2F5,EDNRB,TMTC1,FSD1L,RBM12,SH3GLB1,TENM1,RGS17,PCOLCE2,STARD3NL,CALCRL,EPB41L1,EPB41L2,LRRC17,DENND4A,IGSF6,ZNF549,APC2,FAM198B,DLC1,CEP78,SLC9B2,MED12L,FGFR1,MAD2L2,POLK,UBE2E3,MEX3B,SYNCRIP,SEMA4D,NELFCD,TMEM107,SMC2,UFM1,PDLIM5,FAM49B,ATP6V1H,ATP2C1,KHDRBS3,DACH2,CSPG5,ZNF512,PHYHIPL,MEGF10,GABRA1,GABRB3,GABRG2,HBS1L,ZMYND11,DISC1,ACSS1,KIAA1841,MYOZ2,ALDH1L1,MSTN,WASHC2A,AHDC1,PCDH11X,DCLK2,GPD2,TDRKH,LPAR4,GPR34,GRIA1,GRIA2,GRIK2,NR3C1,GRM5,GRM7,KIF3A,LINC00839,RNF165,ZBTB49,IRAK3,ELOVL5,HMGB1,HNF4G,HNMT,OPALIN,AGFG1,TCEAL6,DHX35,HSF2,IGF1,GAREM2,USP54,SLC35G1,KCNJ3,KCNK3,GATD1,CREG2,KIF5C,CYP27C1,INSYN2,LIFR,VWA5A,HECTD2,LSS,CLEC18A,MAP2,MAP4,LYPLAL1,MBD1,LRP1B,MEF2C,KCTD6,PPM1L,AFF1,WDR49,MOBP,CCDC80,MSI1,MSR1,MTR,HS6ST3,MYBPC1,MYO5A,MYO9A,NEXMIF,BEX5,NAP1L1,NAP1L3,ZC3H12B,NEK1,CNOT4,NOVA1,HCN1,NTRK3,NUCB2,PCSK2,PDE3B,PDE4A,PDE4D,GPR85,PFKFB2,PFKFB3,ABCB1,NALCN,PIK3R1,CCSER2,GPSM2,FAM216A,MTRF1L,LRP12,SCHIP1,PRRX1,ING3,RETREG2,SLC36A4,MINDY2,PPM1B,CCDC144B,PPP2R2B,RANBP3L,GDPD1,SNRK,PSMD13,CNTLN,PTN,ZIK1,PEX2,ZSCAN2,ZNF615,TUG1,TMEM255A,FAM66C,NWD1,ZCWPW1,ZNF493,RASGRF1,RADX,KHDRBS2,TRIM68,REV3L,GTDC1,NUDT11,RAVER2,CARF,ROBO1,PCMTD2,CCDC102B,RPE,TMEM100,ZC3H14,RPL38,ADAL,TCP11L1,LGR4,RPS20,ATAT1,WLS,RTKN,RTN1,ZNF568,DGLUCY,AMER2,SATB1,ATXN1,SCN2B,FAM19A1,SCP2,SLC30A10,SELL,MRAS,TRA2B,SCAF8,NLGN4Y,SH3BGR,ITSN1,PPP1R9A,PPM1E,DOCK10,CHD9,FNDC3A,SLITRK3,CLSTN1,ABLIM3,PPP4R3A,RUFY2,SLC6A1,KANSL3,ZNF430,RADIL,RAB3GAP1,SLC8A3,ARHGEF40,CCDC88A,SHANK2,ELMO2,SLCO1A2,TET1,CPEB4,ZNF667,LIMCH1,SNCA,PALLD,DOP1A,SON,PDZD2,TNIK,KIF21B,GLT8D1,CAND2,UHRF1BP1L,SPP1,TEX2,PEG10,KIF1B,CDK19,RBM26,LMO3,C11orf87,SMOC1,NKAIN2,CEP68,ADHFE1,NECAB1,PRRC2C,ARHGEF9,NUDT10,SYT1,SYT4,ATP11A,DDHD2,MCF2L,TAF9,DNMBP,PDLIM2,ADGRL3,ANO4,DMXL2,SATB2,TRIM2,WDR7,AZIN2,DOCK9,CRTC1,RNF216P1,PMS2CL,SPX,AKTIP,SLC44A1,TIAM1,TLR4,ERCC6L2,TMPO,DAAM2,BEX4,TPM1,TPM3,C9orf85,STXBP4,TRPC3,TSN,TTTY15,CLHC1,TMEFF2,AMOT,DNAJC12,FLRT2,PLEKHH2,CCDC14,XRCC4,MICU3,CELF4,ZBTB38,PLPPR5,WNK1,PRDM2,PRTFDC1,SLC38A1,CSDE1,MDH1B,TMEM163,CAB39L,MVB12B,PLSCR4,PARP11,C12orf4,DNAH10,FAM13C,SMIM8,FBXO36,NUP214,JMJD1C,RNF170,ZDHHC20,SSPN,NETO2,RNF146,SOCS4,CPNE4,SPATA13" MicroRNA hsa-miR-199b-5p:mirSVR_lowEffct hsa-miR-199b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-173 5.89E-170 8.79E-172 8.09E-171 442 1844 "TTYH1,DGCR6,ABR,ACHE,ACLY,ABHD6,KDM5D,FAM43B,CSMD3,TMEM132B,ERMN,PLEKHH1,USP31,RNF150,BEND6,SLC24A4,AP2A2,KCTD16,HACE1,TBC1D14,OSBPL8,CC2D2A,TAOK1,SEMA6A,ALCAM,ABCD2,ARHGAP20,SYT13,AMPD3,ANK2,SUGT1P4-STRA6LP-CCDC180,UPRT,APP,CDK10,TMEM263,TMEFF1,ARRB2,CADPS,MARK4,ASPH,BRINP2,CCAR2,ATP1B3,ZNF582,DPY19L3,ATP6V0A1,TTLL9,ADAM15,BACH1,ADGRB2,BBS2,BCHE,BCL2L2,BID,PROM1,KSR1,SYNJ1,ARHGEF7,MTMR2,BSN,RAB29,WASF1,MYRF,BTRC,CA8,CACNB2,CACNB4,CALB1,PTBP2,CAMK2B,VSTM2A,CH25H,PRC1,CBLN1,ZNF501,CCKBR,METTL6,LRBA,CDH2,CDH8,LOC730101,DLGAP1,CLGN,CBARP,CHRNB2,KMT2C,RAB33A,PPT2,SLC24A2,ABCG2,SULT4A1,SRP14-AS1,HECTD1,NIPBL,AKAP7,AKAP6,COL9A1,MYRIP,ZNF385A,SLC35F1,PNKD,CREM,TENM4,SEC24C,ARHGEF10,PDE4DIP,RASGEF1C,SLITRK5,KIAA0040,GREB1,NRSN1,PUM1,ST18,DCAF4,BOC,DCAF8,INTS1,IP6K1,BRINP1,ARMCX4,HEPH,ZC3H11A,DDX46,PLPPR4,SNAP91,SRGAP3,ARNT2,DMD,DNM1,DNAH9,NR1D2,SLC12A6,DPP6,DPYSL2,DRP2,GNE,DYRK1A,ABCC5,E2F5,EDIL3,EDNRA,EDNRB,HEYL,FRY,YAF2,SUGP2,KMT5B,EIF4G2,IRAK4,ELAVL4,EPB41L1,DMTN,LRRC17,DNAJC27,F5,CLVS1,EFEMP1,FCGR1A,TOMM40L,FCGRT,KAT8,ZNF589,FGF11,PRKAG2,SUCO,MEX3B,PCYOX1,ANKFY1,AKAP3,JKAMP,CINP,TPK1,NPTN,ZNF605,ERGIC3,DACH2,AP4B1,NRG3,OGA,MEGF10,GABRA1,GAD2,HBS1L,BRPF3,ZMYND11,ARPP21,ZNF274,IP6K3,DISC1,SRRM4,KIAA1841,GATM,ALDH1L1,MSTN,WASHC2A,SESN1,MMADHC,USP19,GGT7,MALT1,TCERG1,COPS8,MAP7D2,GNAS,NUDT21,GRB10,GRID1,GRM1,LINC00839,GYG1,WIF1,IRAK3,HPS5,NCKAP1L,MIER3,HLF,VSIG4,ELOVL5,HNMT,NEGR1,ICA1,LINC00667,ZNF546,GAREM2,SCIN,OLFM3,KCNC1,KCNJ3,KTN1,STMN1,HECTD2,MAP2,MAP4,MATN2,SYT9,LDLRAD3,PPM1L,POC1B,MITF,AFF1,MN1,MPP2,RSPO2,MYCN,MYO9A,RTL5,NAP1L2,NEFM,NEFH,NEK1,NEUROD1,NOS1,NOVA1,SLC11A2,HCN1,NTRK3,IGSF11,OCRL,ODF2,OMG,GLIPR1L2,PCMT1,PDE3A,PDE4D,PDGFRA,ENPP2,TMOD2,CDK14,SERPINE2,PIK3R1,FAM218A,A2ML1,GPSM2,SLC25A23,PLXNB1,PURG,PMP22,ING3,SH3KBP1,FSD1,POU6F1,PPM1B,RASGEF1B,PRKCB,EPDR1,MAPK7,MAPK9,GRAMD1C,GON4L,MDGA2,TMEM104,WDR25,CNTLN,PTHLH,PTK2,STK32A,PTPRD,PTPRE,PTPRG,FAM120C,PTX3,ZNF615,PPP2R3C,TMEM255A,FAM66C,FAM184A,ROGDI,RASGRF1,ARID4A,DBX2,BSDC1,MORC4,GTDC1,RFX3,RFX4,SLC25A36,PBRM1,SUGCT,CARF,CCDC25,TMEM100,RPL15,UEVLD,MAP6D1,RPS20,TRAPPC13,DGLUCY,ATXN7,HOGA1,SCN3A,TNFRSF19,ASIC4,PPP1R9A,FBXO11,FNDC3A,R3HDM2,ST6GAL1,CNKSR2,SLC2A5,BTBD3,ZNF430,RAB3GAP1,SLC12A2,NAPB,SCMH1,ELMO2,NAXD,SLN,INAVA,RIMS1,MAPKBP1,SNRPN,PALLD,FAM126B,MYO16,PDZD2,SOX5,SP4,MYCBP2,KDM4C,PEG10,SPTB,ATP10B,STOX1,CEP68,GANAB,SYT11,MLC1,ZFR2,VPS13A,TMEM150C,ARC,SYN2,SYPL1,TAC1,TACC1,TAL1,FAM208A,FBXW11,KLHL4,VWA3A,EHBP1,ZFP90,TPCN2,TRIM2,DOCK9,TMEM151B,FAM189A1,SLC19A3,HIF3A,TEK,ATP13A2,AP4E1,HHIP,SLC44A1,MTMR14,TMEM9,BEX4,TNR,TPM1,RGMB,PDSS1,STXBP4,TRPS1,TTC3,SGK3,CADM1,FAM155A,SLAIN1,ZNF709,LAT2,ZNF781,NSD2,GUSBP1,CFAP298,ZNF24,ZNF28,ZNF70,NDRG4,MKRN3,CELF4,SMARCAD1,UPF3A,SLC30A4,MAP3K12,PRDM2,SLC38A1,RGMA,GDPD5,LINC02210,PRDM10,RNF103,SCG2,SLC17A6,RGS7BP,FZD3,NUP214,ADAMTSL3,JMJD1C,FXR1,NETO2,JPH3" MicroRNA hsa-miR-1299:mirSVR_highEffct hsa-miR-1299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-173 7.64E-170 1.12E-171 1.04E-170 450 1912 "ABAT,KCNH8,CLK4,ACTN2,TMEM132B,ADCY6,ERMN,KIAA1211,KIDINS220,AP2A2,GPR158,KLHL13,WDR35,TXNDC16,PLA2G6,C1QTNF1,LRRC7,SPOP,BBOX1,DPP10,CCDC146,PARG,APBA2,APLP1,UPRT,GPAM,LGR5,MIER1,PLA2G4C,ARSF,CDK13,MARCH3,CCDC74A,ASPH,NUMB,ATP1B3,ATP2A2,ATP2B1,ZNF582,SLC2A11,RNF182,ADAM23,RGS9,BCL2L2,NRP2,BID,CFLAR,PROM1,DST,SYNJ2,ARHGEF7,MTMR2,CA8,CACNA1D,CACNB2,KALRN,CANX,CAST,SPAG9,MAP7,CBR1,CD86,CBFA2T2,TMEM257,CDC27,CDC42,ZMYM4,LGI1,MAGI1,NUMBL,CFL2,SYNPR,NDST3,KMT2C,PLAA,CLCN3,TPP1,CLTC,NGEF,C4orf33,FHL5,AKAP6,BTF3L4,SLC4A8,RCHY1,SMARCAL1,TOGARAM2,MYRIP,IGDCC3,SLC35F1,CRMP1,GDA,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,CNTNAP2,UBXN2A,PHF14,PNPLA8,CTH,CTNND1,PUM1,EDRF1,CX3CR1,CYBB,BOC,DOCK4,RIPOR2,TOX,KIAA0513,IST1,DGKB,ZEB2,CEP170,DDX46,RHOBTB1,G3BP2,DLG4,HS3ST2,DNAH9,CD99L2,DRD1,DNM1L,E2F6,AASDH,EDN1,ANKRD46,CNNM1,TMTC1,YAF2,FAM13A,PHF20L1,MRO,MBNL2,AASS,EIF5,PLEKHA1,TNK2,TMEM35A,EMX2,EPB41L2,RCAN2,RASGRP2,EPHB1,ENPP6,RABEPK,STX2,ERCC2,NCALD,EFS,CEP85L,TMEM74,VPS26C,RCSD1,ADGRV1,EFEMP1,FER,FHL1,SUCO,SEMA4D,ATP13A4,ANKFY1,NELFCD,EFCAB2,SORBS1,ZNF605,ST6GALNAC3,MSANTD4,TVP23A,GABRA1,GABRA2,HRASLS5,ZMYND11,GALC,TMEM8B,MTHFD2,DISC1,LRRC37A6P,GATM,ALDH1L1,GCNT2,MSTN,GGT7,TCERG1,ZNF638,LUZP2,GNAS,WDFY3-AS2,GPM6B,GPR12,B4GALNT4,ATP2B1-AS1,GRIA2,RFFL,NR3C1,GRM7,ZNF496,KIF3A,MFSD2A,RABL2A,PSIP1,RNFT2,GUCY1B1,WIF1,MIER3,SYNPO,ZDHHC15,LRRC75A,IRF8,IL6ST,LRRTM3,ITGAM,KCND1,KCNJ10,KCNK2,KCNMA1,KLC1,KPNA5,STXBP5,TTYH2,HECTD2,NCOA7,LSS,PIK3AP1,MAOB,MAP6,MAT2A,SYT9,MDM4,MEF2C,MEIS2,MEST,KCTD6,MMP16,MOBP,CD200,CTNNA3,MX1,PABPC1L2A,NEUROD1,NF1,CNOT4,PCBP3,NTRK2,NUCB2,IGSF11,CHAMP1,OPA1,CLDN11,PAK3,PCSK1,PDE4D,PDGFRA,GNG2,BEST3,PFKFB2,OLA1,SERPINE2,SERPINI1,CCSER2,XRN1,SLC25A23,SMIM7,TRHDE,LRP12,EXOSC10,EPB41L4B,POU3F2,MED1,PTPA,PPP2R5E,RANBP3L,CEP41,PRKCB,HYDIN,GDPD1,MASP1,VPS13C,MDGA2,PTK2,PXK,ZIK1,PTPRG,FAM120C,C1orf109,ZSCAN2,ZNF615,SLC25A48,FAM66C,OXR1,RDX,ZYG11B,ZMAT4,GTDC1,PBRM1,SUGCT,C12orf49,CARF,ELP2,RPE65,NEK11,SPIN3,ATP8B4,RPS6KA2,MAP6D1,KCNIP1,ZNF568,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,LRRTM4,SCP2,TNFRSF19,ELMOD1,NLGN4Y,SH3BGR,ITSN1,ARX,MAGI3,CHD9,FNDC3A,FHOD3,NLGN1,NUBPL,PAAF1,WDR37,ZNF365,SLC2A5,RUFY2,SLC6A11,KDM4D,CCDC88A,SLC11A1,SLC15A2,SLC22A4,NAXD,CXXC4,CDK5RAP2,SMARCE1,RCOR3,LIMCH1,SNAP25,KIF13A,LMBRD1,FNBP1,SP4,ENKUR,GLT8D1,ZC3H13,C11orf87,TAB2,CLASP2,CLSTN2,POGZ,ITPRID2,SMOC1,NKAIN2,STAU1,CEP68,DIP2A,ADHFE1,FGD4,ZC3H4,PRRC2C,COBL,ANKRD28,TACC1,TACR1,ANKRD12,MCF2L,DNMBP,TBCEL,ANO4,TCF7,TCF7L2,TPCN2,TCF12,USP22,CLASP1,SYNE1,RALYL,OBSL1,FRYL,CCDC173,TEX15,DICER1,ZFPM2,CHST8,CRB1,AP4E1,GPR161,TGFBR3,ZNF34,HHIP,SLC44A1,TIAM1,ACTR6,ERCC6L2,TMOD1,TMPO,RIMBP2,TPD52,SYNPO2,DCBLD1,TSN,RFTN2,RPL7L1,SLC35A4,UBE3A,AMOT,UGT8,PLPPR2,CCDC14,BEST1,NSD2,CFAP298,ZBTB14,ZIC1,TRIM9,AGMO,NDRG4,CELF4,ZBTB38,PLPPR5,SMARCAD1,UPF3A,SLC30A4,MFF,CSDE1,PCDH15,NAV3,KCNAB1,WNK3,EPM2A,HRASLS,ST7,HNRNPA3,PHTF2,FBXO36,CASC15,TRAM2-AS1,RNF170,MSRB3,FXR1,FRMD6,SLC4A10,FAM198A" MicroRNA hsa-miR-519b-3p:mirSVR_highEffct hsa-miR-519b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-173 8.66E-170 1.26E-171 1.16E-170 387 1410 "KCNH8,NCKAP5,ADCY6,GALNT13,KIDINS220,SLC24A4,ZNF608,GPR158,HFM1,LRRC7,SPARCL1,SRPX,ABCD2,ARHGAP20,MRTFA,OGT,LRCH2,SEMA7A,EP400,USP28,API5,SHTN1,LINC00173,STK33,CAPRIN2,RASL11B,ATM,SLC4A4,ATP2B1,ZNF583,B3GALT2,NOL4,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,IL33,HIP1R,MAP7,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,ZFYVE9,IGLON5,BTF3L4,SLC4A8,RCHY1,AHCTF1,HS3ST5,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,CHD5,PITPNM3,UBXN2A,PHF14,NRSN1,PPP6R2,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,MYEF2,FBXL5,MAGI2,PLPPR4,SACS,WDR20,DMD,USP3,DPYSL2,DNAJB6,DYRK1A,DNM1L,ABCC9,EBF1,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,CALCRL,CEP85L,RASL12,EZH1,F3,ACSL4,TAOK3,CEP78,TESK2,SLC9B2,FGF13,FGF14,PRKAG2,MEX3B,FOXG1,FOXF2,RGPD5,JKAMP,NBEA,UFM1,ATP2C1,NSG1,GAB1,GABBR1,GABRA1,GAD2,B4GALNT1,ARPP21,ERAP1,DISC1,MYOZ2,SULT1C4,ZNF276,GLS,TOX3,ZNF638,LUZP2,GNAL,RAPGEF4,GRB10,ADAMTS8,PRDM5,GRM5,GRM7,CIT,LINC00839,RNF165,RABL2A,PSIP1,GUCY1B1,HAS2,HPS5,NXPH2,FRMD3,MIER3,TLX1,IRF8,DOCK7,LRRCC1,ZNF678,JAK1,KCND2,KCNJ10,KCNK1,KCNN2,CREG2,KIF5A,KIF5C,LIG4,FGFBP3,ARHGAP12,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,MDM4,LRP1B,MID1,MITF,XRRA1,MOG,ERICH3,BCO1,MSR1,RSPO2,MXI1,LAYN,MYT1,NACA,NELL1,NELL2,NEUROD1,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,NTRK2,OCRL,GPR88,P2RY1,GPR137C,CNTN3,PDE3B,PDGFRA,GNG2,BEST3,CCSER2,TMEM38A,JAKMIP1,SCHIP1,PMS2,EPB41L4B,PPM1B,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PKIA,MASP1,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTHLH,PTPRB,ACSM5,ZSCAN2,QDPR,RAB5B,PID1,CEP97,SLC25A48,USP47,RAD17,ATG16L1,OXR1,ARID4A,RBBP6,ZDHHC14,ZYG11B,TRIM68,RET,RFX3,RFX5,SLC25A36,ZFHX4,CCDC82,SETD5,RAVER2,PNMA8A,ROBO1,RORB,UEVLD,ZNF671,LRRK2,CNTNAP3,RTN1,RYR3,SALL1,CSRNP3,HOGA1,SCN3A,FAM19A1,LINC00461,PRCD,SCP2,HSPA4L,ITSN1,PPP1R9A,ARX,KIF16B,CPEB3,SHC4,CHD9,SLITRK3,SYBU,PAAF1,FAM81A,RUFY2,KANSL3,LRRC55,RAB3GAP1,CCDC88A,BTBD7,NAXD,RCOR3,ANKRD36,KIF13A,SNRPN,TMCC1,KDM4B,USP33,MYT1L,TRERF1,SOX5,DOK5,TEX2,IQSEC2,SPART,C11orf87,CLASP2,TROVE2,POGZ,SMOC1,LARP4,ERBIN,ADHFE1,GANAB,NECAB1,PLCB1,SYT1,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,RALYL,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,TGFBR3,AKTIP,SLC44A1,THRA,TLR4,HEY2,R3HDM1,STXBP4,TRPC1,TSC1,UBC,FAM155A,UBE3A,SLAIN1,PITPNB,FLRT2,VLDLR,TBC1D15,NSD2,XPO1,PCDH20,ZBTB14,ZNF711,ZNF45,ZNF74,MKRN3,TCEAL7,CELF4,REEP1,FSTL5,ANKS1B,CA10,MAP3K12,MFF,CSDE1,CAB39L,FAM47E,WNK3,SLC17A6,PLSCR4,RGS7BP,SMIM8,PHTF2,CASC15,SSPN,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-377:mirSVR_highEffct hsa-miR-377:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.30E-173 1.29E-169 1.85E-171 1.70E-170 416 1636 "DPF1,ARID1A,XKR4,TMCC3,ADD2,SORCS1,PWWP2A,AP2A2,INTS2,CC2D2A,SPOP,ALCAM,PCDH10,MRTFA,AMPD2,KIF6,NT5C3B,BCAS1,LGR5,MIER1,MADD,ARHGAP5,MARCH3,NCOA1,NUMB,RASL11B,ASTN1,RNF182,BARD1,BBS2,NRP2,PROM1,SYNJ1,MTMR2,JAZF1,WASF1,IL33,CA8,CACNA2D1,CACNB2,CACNB4,PTBP2,CAST,SPAG9,RUNX1T1,USP6,INA,CACNA2D2,CIART,CFL2,SRSF11,CASC2,SYNPR,B4GALT6,CNOT8,RAB28,QKI,HOMER3,ARMC8,AKAP6,ACBD5,ZFP28,HS3ST5,CSF1,CSNK1G3,VAC14-AS1,PLXNA4,DZIP3,PITPNM3,ERC2,APPL1,PHF14,CTNND2,PUM1,HDAC9,FGFR1OP2,GAPVD1,TOX,KIAA0586,IP6K1,DNAJC6,ZEB2,ELMO1,HP1BP3,KIAA0319,MAGI2,KLHL3,FBXO25,RHOBTB1,SMG7,PLPPR4,NTM,G3BP2,CHRDL1,DLG2,DMD,DNM1,CDON,GNE,DTNA,ECM2,MAMLD1,DNAJB6,ABCC9,AASDH,EDNRB,ANKRD46,HIPK3,RBM12,YAF2,TENM1,PCOLCE2,EML1,C8orf37,VPS13B,EPB41,KCNMB2,ENPP6,DENND4A,CLVS1,FAM198B,ACSL4,SCML2,DLC1,SPSB4,FGFR1,TMEM164,AMOTL2,CAP2,SLC37A3,JKAMP,TRMO,NBEA,ZCCHC17,PDLIM5,CELF1,STAU2,SARAF,ILDR2,GAD1,GAD2,AHCYL1,BRPF3,GALC,ARPP21,SALL3,IQGAP2,DISC1,ATP8A2,KIAA1841,SESN1,RUNDC3A,HPGDS,GLDC,GLYR1,GLS,MSL3,PCDH11X,ZNF638,DCLK2,GNAS,ZNF782,PRUNE2,GPM6B,TDRKH,GRIA1,GRIA4,PLCD4,NR3C1,GRM5,RNF165,PSIP1,RASSF8,PADI2,NXPH2,NCKAP1L,ELOVL5,HMGCR,NEGR1,HSP90AA1,HTR2A,MSL1,C5orf24,ZIC5,RBPJ,IL11RA,ITGAM,KCNA2,KCNA4,KCNA6,KCNJ3,KCNJ11,KCNMA1,KIF2A,KLRC2,KLC1,IPO5,STXBP5,LAMP2,LIG4,SFXN5,VWA5A,HECTD2,NCOA7,MARK3,MAT2A,MBD1,MBNL1,SYT9,TM6SF1,AFDN,MMP16,MSR1,MSRA,MXI1,NAP1L1,NCAM1,NELL1,NFE2L2,NKX2-2,NPY,NOVA2,DNHD1,SLC11A2,NRCAM,ODF2,GPR88,OPA1,OPHN1,PCDH8,PCSK1,PCSK5,PCSK2,PDE3A,PDE4B,PDGFRA,GPR85,GNG2,HERC2P3,DUSP26,GDAP1L1,SSH1,NALCN,CCSER2,KCTD15,PLCB2,PLCL1,TRHDE,LRP12,RETREG2,POU3F2,PPP2R5E,EPDR1,BCAS3,VPS13C,LAMA1,CNTLN,PTCH1,PXK,TMEM260,STK32A,PTPRO,ZNF793,FAM184A,ENOX1,ZNF493,OXR1,ARID4A,RBBP8,RDX,SLC6A15,ERI2,FIGN,ARHGEF10L,TTLL7,SEC61A2,SETD5,KLHDC8A,CARF,GSTCD,PCMTD2,CCDC102B,RPE,SNX22,FBXW7,ATP8B4,LRRK2,ABCA11P,ZNF568,FAM192A,CSRNP3,SLC30A10,COPZ1,SGK1,ZFP30,CHD9,NLGN1,ANKRD6,PAAF1,WDR37,ZNF365,RPH3A,RAB3GAP1,SLC12A2,SLC12A4,NAPB,CPEB4,OGDHL,DMRTC1,MBD5,PALLD,UNC80,SON,ZSWIM8,CLUAP1,EMC1,SPP1,KDM4C,ARHGAP26,CDK19,NPAS3,SRPK2,TAB2,CLASP2,TROVE2,ITPRID2,SAMSN1,ZC4H2,LARP4,NXT2,ELOVL4,DIP2A,STX1A,STXBP1,AJAP1,SYT11,PLCB1,MMS19,TACR1,CAMTA1,UNC5D,ADGRL3,TBCEL,TBL1X,ATMIN,SATB2,TCF7L2,ZEB1,RPGRIP1L,TCF12,PUM2,TF,FAM200B,AP4E1,AKTIP,TIAM1,ACTR6,ASXL3,BHLHB9,TMOD1,TMPO,KCTD2,KAT6B,TPM4,SYNPO2,PRMT8,TTTY15,CLHC1,TMEFF2,SGK3,CADM1,RPL7L1,EIF4ENIF1,UGT8,OSBP2,ZNF709,VGF,CCDC14,NSD2,RICTOR,XRCC4,PCDH20,ZNF711,ZNF708,ZNF540,NDRG4,TCEAL7,ZNF154,REEP1,LAMP5,PLPPR5,DHX33,ZNF225,ZXDA,LRP8,STMN4,STOX2,PRDM10,ADAMTS9,SCG2,NAV3,CAB39L,WIPF2,C12orf4,PDSS2,FZD3,KAT6A,SMIM8,PHTF2,CAMK1G,ADAMTS10,IFT88,NETO2,NETO1,SLC4A10,FAM198A" MicroRNA hsa-miR-1272:mirSVR_lowEffct hsa-miR-1272:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.40E-173 3.60E-169 5.06E-171 4.66E-170 450 1919 "TKTL1,ACTN2,XKR4,CSMD3,KLHL32,PSMG3-AS1,AXIN2,SORCS1,PLEKHH1,GRAMD1B,RNF150,KIDINS220,AP1B1,INTS2,HECW2,PCDH19,KCTD16,OSBPL1A,NME5,KIAA1324,OSBPL6,WDR35,CC2D2A,SEMA6A,CEP126,PCDH10,SYT13,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DGKZ,TNRC6C,USP37,CPNE5,LGR5,SHROOM2,PPP4R4,TMEM263,IGDCC4,ZSCAN18,DACT3,ATP1A2,SLC4A4,ATP2B1,B3GALT2,ATP6V0A1,BCL2L2,MIR9-3HG,CFLAR,PROM1,BMPR1B,ARHGEF7,NIPA1,BTRC,DDR1,CACNB4,LURAP1,THSD7A,VSTM2A,ISPD,MAP7,CBFA2T2,C1orf52,ZBED1,DCLK1,SOCS6,CASC2,NRXN3,CLCN3,CLTC,QKI,AHCTF1,SMARCAL1,ZFP28,MFSD4A,SLC35F1,CREM,CLIP3,SNCAIP,CSF1,RGS6,SIPA1L1,CHD5,RIMS4,CNTNAP2,PLXNA4,PPP1R16B,SDC3,ERC2,UBXN2A,PLCXD3,ZSCAN23,USP6NL,CX3CR1,CCDC144A,KIAA0408,DOCK4,ARHGAP32,KATNAL2,EARS2,TBC1D5,KCTD8,DGKB,DGKG,DAPK1,ARMCX4,PITPNC1,ARMCX2,ELMSAN1,JAKMIP2,DGCR5,ZEB2,BLOC1S6,POM121,AK5,G3BP2,RABGAP1L,DLG2,DLG3,EXOG,GRIN3A,RAB39B,DMD,DNM1,HS3ST4,SLC29A4,DMTF1,DPP6,DRD1,PDCD6IP,ABCC5,SNX29,FAM135B,EDNRA,ATL1,SEMA3D,FRY,SH3GLB1,FAM13A,MBNL2,KCTD3,EIF4G2,COPS4,TENM1,C8orf37,EN2,RCAN2,EPHA5,KCNMB2,STX2,SRRM1,EPS8,NCALD,IGSF6,ZNF549,ETV1,DNAJC27,SIRPB1,EXTL2,ADGRV1,F5,TUBA1B,ATP8A1,TOMM40L,FKTN,ZNF589,FER,FGF14,FGFR1,CAMSAP1,SUCO,CAP2,SYNCRIP,FLT1,ANKFY1,NELFCD,WDR83,JKAMP,SMC2,TPK1,KHDRBS3,DACH2,SARAF,DOT1L,OGA,MEGF10,GAB1,GABRA5,GABRG2,FAM120B,GALC,ARPP21,ATP8A2,CPLX2,GPR162,CYP46A1,PPARGC1A,GLRB,PCDH11X,ZNF638,HTATSF1,GPD2,FUT10,NUDT21,GRIA1,PLPP7,ZNF496,TMEM25,AP4S1,FAM107A,ADAMTS6,GUCY1A1,SLC2A6,VSIG4,HMGCL,ZNF491,ZDHHC15,CPT1C,TCEAL6,HSF2,HTR5A,FAM95B1,C2orf72,GAREM2,IL6ST,KCNA2,KCNC1,KCNJ3,KCNK1,KCNN2,CREG2,KIT,KLRC2,KLC1,STXBP5,CYP27C1,LIFR,LIMS1,SYTL4,C2orf80,GPR155,ZFYVE27,LDLRAD3,TM6SF1,MEIS1,MID1,MN1,JAKMIP3,BLOC1S2,HS6ST3,MXI1,BEX5,NAP1L1,FXYD6,NAP1L3,RCOR2,NEUROD1,OTOGL,DNHD1,SMIM11A,PAH,GLIPR1L2,DPY19L2P2,PDCD2,PDYN,GPR85,CDK14,NALCN,PIK3R1,ZNF655,GPSM2,ST8SIA5,FTO,PRIMPOL,PMP2,STRN3,LRP12,SCHIP1,PRRX1,MAGEL2,NXPH1,POLR2F,DRAM2,PPM1B,CRLS1,KANSL1,PRKCB,MAPK9,HYDIN,BCAS3,VPS13C,CYBC1,SIDT1,MDGA2,CNTLN,UHRF1BP1,PTPRB,PTPRE,FAM120C,PEX5,NKAIN1,PLEKHB2,ZNF793,SH3TC2,ZNF493,RDX,SLC6A15,SLC25A36,DCUN1D2,C12orf49,ARMC5,RAVER2,PNMA8A,ROBO1,CCDC25,PGBD4,EPHA10,SPIN3,PRR5L,RPS6KA2,RYR3,ZNF331,FAM192A,FOXRED2,SATB1,ATXN1,ATXN7,SCP2,SMPD3,GALNT10,ZFP30,PPM1E,FERMT1,FBXO11,ST3GAL3,ABLIM3,SLA,LRRC55,SLC8A1,RAB3GAP1,SHANK2,SLC12A2,NAPB,BTBD7,SLC22A4,CPEB4,NAXD,GKAP1,SORCS3,SMARCD3,RCOR3,ANKRD36,LIMCH1,KIF13A,LMBRD1,SCN3B,TRERF1,SOX2,SOX5,BDP1,FNBP1,IDI2-AS1,PEG10,SPTAN1,C11orf87,TAB2,CLSTN2,NKAIN2,STAU1,ZSCAN29,ELOVL4,DIP2A,STX1A,FGD4,PRRC2C,RHBDL3,ARHGEF9,FNDC9,PLCB1,SYPL1,TACR1,ANKRD12,TAF9,CAMSAP2,KLHL4,TBX15,VWA3A,EHBP1,TCF4,ZEB1,TPCN2,TRIM2,RALYL,PCDHB9,SLC19A3,PCDHB7,OBSL1,USP32P1,HIF3A,FAM200B,DICER1,AP4E1,TGFBR3,HHIP,AKTIP,CDH22,FAM124A,RIMBP2,KCTD2,TPM1,PRMT8,TRPS1,PPIL6,TSN,SSBP2,RFTN2,CLHC1,HIRA,SGK3,SLAIN1,ZNF709,VAV2,LMF1,RICTOR,GUSBP1,ZNF23,ZNF24,ZNF28,ZNF45,ATP6V0E2,ZNF70,FMN2,AMZ1,ZNF184,SMARCAD1,SLC38A1,PRDM8,LMAN2L,KCNAB1,CAB39L,WIPF2,MPPE1,PARP11,FZD3,FBXO36,ADAMTSL3,TTC7A,FXR1,AP3B2,FAM198A" MicroRNA hsa-miR-1259:mirSVR_highEffct hsa-miR-1259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.43E-173 4.18E-169 5.80E-171 5.34E-170 412 1609 "ABCF1,FMNL2,DSCAML1,KLRC4,ERMN,KIAA1211,SLC44A5,WDR35,TAOK1,LRRC7,ALCAM,ARHGAP20,BBOX1,FAM135A,AMPH,ANK2,PHF12,PARG,APAF1,GPAM,ALS2,AQP4,ARHGAP5,CADPS,ASPH,ATP1A2,SLC4A4,MYOM1,ADAM23,BACH1,SEC11C,DST,IL33,KALRN,PTBP2,CAMK2D,CANX,CBS,METTL6,DGKI,LRBA,SEPT7,CDC27,CDC42,FOXN3,SOCS6,CASC2,PLAA,NGEF,FBXO7,TJP2,TMEM155,CNN3,CNR1,FAM149A,SLC4A7,SLC4A8,ABI3BP,RCHY1,ACBD5,ZFP28,NECTIN3,PREPL,CREM,HAPLN1,TRIM69,LRIG1,ARHGEF10,ATRNL1,VCAN,SOCS5,PDE4DIP,PHF14,GREB1,CTNND1,DOCK4,HDAC9,GPRASP1,ARHGAP32,KATNAL2,FRMPD4,LIN54,DAPK1,SIRPA,ARMCX4,ARMCX2,C8orf34,MYEF2,RABGAP1L,WDR20,DLG2,DLG3,DMD,DNM1,DPP6,ECM2,WDPCP,OPTN,YAF2,PHF20L1,GOLGA7,IRAK4,USPL1,RCAN2,TLR7,RRAGB,EYA1,ARMCX1,CLVS1,ABCA8,ZNF461,RPS6KC1,TAOK3,DLC1,ZSCAN30,FDFT1,FER,KIAA1109,FGF11,FGFR1,POLK,FLT1,SGIP1,JKAMP,NBEA,TRIM16,ATP6V1H,ST6GALNAC3,STAU2,DOT1L,PHYHIPL,STAG2,GABRA2,CHL1,GABRG2,GAD1,HBS1L,AHCYL1,FAM120B,RAPGEF6,NCKAP1,DISC1,GATM,GDF9,ADAM28,GHR,PPARGC1A,KIRREL3,GK,TXNL4A,GLS,MSL3,ZNF782,ADGRA3,LILRA1,GPR22,EML4,CECR2,FAM19A2,BVES,GUCY1A2,MAP4K5,HPS5,NXPH2,BACH2,HMGB1,SCRG1,HNMT,NEGR1,SMAP1,MSL1,C5orf24,LIX1,LRRTM3,KCNA2,KCND2,KCNH2,KCNJ3,KHK,CREG2,LIMS1,PAXBP1,HECTD2,ARHGAP12,LYPLAL1,MATN3,MEF2C,KCTD6,AFDN,MMP16,CD200,ERICH3,ZNF680,MRPL42,JAKMIP3,ADAM22,RSPO2,PABPC1L2A,NAP1L1,NEK1,NEUROD1,HCN1,NTRK2,NTRK3,DDR2,IGSF11,GPR88,OLR1,PAH,PAX6,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDCD2,PRTG,PDE3B,PDPK1,GNG2,OLA1,NALCN,ZNF655,PCDH18,HMGCLL1,PDZRN4,TRHDE,MAPKAP1,STRN3,PRRX1,ING3,EPB41L4B,NXPH1,POU3F2,IRX1,MED1,PPM1B,CRLS1,PRKACB,PKIA,MAPK4,PROX1,VPS13C,PSMA6,QRICH1,CNTLN,ANKHD1,PTHLH,PTK2,TMEM260,PTPRD,PTPRE,C1orf109,PTX3,PEX2,TTC13,ZNF793,RALGDS,ZNF493,OXR1,RBBP6,RADX,MSANTD2,RDX,SLC6A15,GTDC1,TTLL7,RIC8B,RPRD1A,ZFHX4,ARMC5,CARF,GSTCD,NEK11,UEVLD,ATP8B4,GLDN,LRRK2,MEG3,ZNF331,CCDC112,ATXN2,CASC3,NLGN4Y,SH3BGR,SH3GL2,PPM1E,CPEB3,MAGI3,FNDC3A,SLITRK3,ANKRD6,ZNF365,PPP4R3A,WDR47,SLC6A1,SLC6A11,SEPHS1,SLC12A2,MTERF2,SLC20A2,ATF7IP,SPHKAP,CPEB4,RCOR3,ANKRD36,RIMS1,SNAP25,SNCA,ZNF415,SNRPN,PDZRN3,USP33,TRERF1,SOX5,KIF21B,SOX11,KDM3A,GLT8D1,PEG10,RBM26,NPAS3,SPART,CLASP2,STOX1,LARP4,ERBIN,NXT2,ELOVL4,DIP2A,NECAB1,VPS13A,FNDC9,SYPL1,COBL,ATP11A,DDHD2,EXOC7,CAMSAP2,FAM208A,ADGRL3,EHBP1,SATB2,TCF7,TRIM2,WASHC4,PCDHGA11,SYNE1,RALYL,PCDHB10,PCDHB4,PCDHB3,NSD1,ARHGEF12,FRYL,TEX15,FAM200B,ZFPM2,AKTIP,ZFP91,ERCC6L2,KAT6B,TRIO,AMACR,STXBP4,SGK3,AMOT,FRRS1L,VLDLR,VSNL1,P2RY12,WRN,GUSBP1,ETNPPL,ZFP37,ZIC3,ZNF17,KCNT2,TRIM9,ATP6V0E2,FMN2,ZBTB16,FSTL5,ANKS1B,PLPPR5,SYNC,CADM2,LRP8,CSDE1,PRDM8,RNF103,TUBA1A,ADAMTS9,PCDH15,TRIM16L,MVB12B,PLSCR4,PARP11,C12orf4,PDSS2,FAM13C,FZD3,SMIM8,HNRNPA3,FBXO36,RNF170,KLHDC1,CBLN2,SOCS4,SLC4A10,GAN,FAM198A,SENP7" MicroRNA hsa-miR-587:mirSVR_highEffct hsa-miR-587:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-172 5.65E-169 7.74E-171 7.13E-170 435 1796 "ACLY,ABHD6,XKR4,SLITRK1,GALNT13,ADD3,SORCS1,PTCHD1,OLMALINC,SLC44A5,OSBPL1A,CC2D2A,C1QTNF3,LRRC7,FAM135A,ANK2,MAP4K3,PPFIA1,PKP4,GPAM,DDO,API5,USP37,CADPS,LINC00173,CAPRIN2,ASPH,DDX3Y,CCDC181,SLC4A4,ATP6V0A1,BBS2,NRP2,DST,SCAPER,NIPA1,CA4,CACNA2D1,CACNB2,THSD7A,CALM1,KALRN,PTBP2,VXN,CAST,BRSK2,SPAG9,RUNX1T1,AIFM1,SCARB1,LRBA,CDC27,CDC42,CDH10,ZMYM4,MAGI1,CDR1,CLGN,DIS3L,CHN2,MS4A7,CNOT8,SLIT2,RAB28,PPT2,NRXN1,QKI,CNGA3,ARHGEF6,ARMC8,ANKRD35,AHCTF1,SMARCAL1,CP,SLC35F1,RBM39,CREB5,RNF14,GDA,CSF1R,ARHGEF10,MICAL2,CSNK1G3,SUSD5,ATRNL1,ERC2,UBXN2A,PNPLA8,SLC45A1,CTNND1,CTNND2,ZSCAN23,DOCK4,KATNAL2,GAPVD1,TCAF1,RIPOR2,FRMPD4,TOX,KIAA0586,MAML1,TMEM170A,C8orf34,HEPH,MYEF2,MFAP3L,ZC3H11A,DDX46,ALKBH8,SMG7,SPOCK3,NTM,AK5,RAB39B,DMD,CPEB2,DRD1,PDCD6IP,DTNA,GOLT1B,E2F6,EDN1,SEMA3D,KLHL5,FSD1L,FAM13A,PHF20L1,EGR3,RASA4,AASS,GOLGA7,PLEKHA1,CALCRL,EN2,KCNMB2,RABEPK,ETV1,RTN3,SCML2,EFEMP1,DLC1,CEP78,TOMM40L,FDFT1,TESK2,FER,FGF12,FGF14,FGFR3,POLK,SUCO,PSD2,PDLIM5,ATP6V1H,DACH2,MPP6,FYB1,MEGF10,GABRA1,GABRA2,GABRG2,GAD1,HBS1L,RAPGEF6,IP6K3,LRRC37A6P,KIAA1841,SULT1C4,ADAM28,GFRA2,PCDH17,PPARGC1A,MALT1,TXNL4A,COPS8,DBF4,RAB30,TNRC6A,PCDH11X,ZNF638,INSM2,GNAS,ZNF782,ADGRA3,GPM6A,TDRKH,STMN2,GRIA2,GRIA4,RFFL,GRIK2,NR3C1,GRM3,FAM19A2,PSIP1,FAM107A,IRAK3,HPS5,NCKAP1L,ELOVL5,HMX1,HNMT,HNRNPK,SMAP1,ICA1,IDH3A,NKD1,DOCK7,SCIN,DIPK1A,ZNF385B,OLFM3,KCND2,KCNN2,KLRC2,KPNA5,LRRC4B,LIG4,HECTD2,FGFBP3,MAN2A2,AQP11,MBNL1,SYT9,MDFI,MEIS1,SRSF12,AFDN,ERICH3,ADAM22,MSR1,ZNF92,RSPO2,ZNF862,MYT1,NACA,NEUROD2,NHLH1,NKX2-2,CNOT4,NPR2,SMIM11A,NUMA1,GPR88,GPR137C,CNTN3,PCDH9,ENPP2,GNG2,CDK14,NALCN,RETREG1,GPSM2,FAM216A,PCDH18,TRHDE,PMS2,NXPH1,MED1,MINDY2,PPM1B,TATDN3,CRLS1,PPP2R5C,PPP3CC,KANSL1,CEP41,PKIA,GRAMD1C,PRPSAP2,SYTL2,QRICH1,PTCH1,MTMR10,PTHLH,TMEM260,TTC13,TMEM231,MARCH1,RAB5B,CEP97,SH3TC2,KHDRBS2,RDX,SLC6A15,ZMAT4,RET,ZFHX4,CCDC82,ZNF532,CARF,GSTCD,ROBO1,ELP2,CCDC102B,EPHA10,FBXW7,GLDN,ADAL,ACER3,TCP11L1,LRRK2,SYNDIG1,ABCA11P,HUNK,KCNIP1,ZNF568,SALL1,MIR124-2HG,SATB1,ATXN7,SCP2,FNIP1,TNFRSF19,GALNT10,SUPT20H,TRA2B,SCAF8,KIF21A,ITSN1,MYO18A,FBXO11,FHOD3,NLGN1,SLC1A3,SLC1A6,RUFY2,SLC6A11,SLC8A1,ARHGEF40,CCDC88A,SLC11A1,SLC12A2,ZNF334,SLC14A1,BTBD7,SLC20A2,ATF7IP,NAXD,ZFP1,SORCS3,SMARCE1,MBD5,SNRPN,PALLD,PDZRN3,UNC80,USP33,SON,WDTC1,MYT1L,TRERF1,BDP1,DOK5,NMNAT2,SPP1,KIF1B,CDK19,LMO3,ATP10B,CLASP2,POGZ,COLGALT2,NKAIN2,ERBIN,NXT2,RGL1,AJAP1,KLHL7,FGD4,SYNE2,DDHD2,CAMTA1,DNMBP,ADGRL3,TBCEL,TMEM136,ACSL6,SATB2,TPCN2,CLASP1,PCDHB3,ARHGEF12,FRYL,FAM200B,DICER1,C18orf54,ITGB3BP,SLC44A1,GZF1,NR2E1,FAM124A,KAT6B,TPM1,C9orf85,METTL3,PPIL6,TMEFF2,HEPACAM,CADM1,UBE3A,SLAIN1,USP1,MEAF6,TBC1D15,WIPF1,P2RY12,ZNF781,NSD2,ZIC3,ZNF23,ZNF28,ZNF32,FMN2,ZNF138,ZNF184,EMSY,EVI5,PRDM10,RNF103,HPS4,PCDH15,CAB39L,MPPE1,PARP11,GOPC,FAM13C,FBXO36,CASC15,JMJD1C,RNF170,KLHDC1,NETO2,SLC4A10,SENP7" MicroRNA hsa-miR-16-1*:mirSVR_highEffct hsa-miR-16-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.57E-172 1.44E-168 1.95E-170 1.80E-169 430 1759 "RALGAPA1,ACADM,NCKAP5,NBAT1,GALNT16,SLITRK1,CCDC85A,PWWP2A,RNF150,SLC44A5,HFM1,SPARCL1,ALCAM,FAM135A,OGT,ANK2,MAP4K3,APAF1,UPRT,ALS2,BCAS1,API5,SHTN1,LGR5,CDC14B,MIER1,CADPS,ASCL1,ZSCAN18,NUMB,ATM,ATP2A2,ATP2B1,ALDH7A1,N4BP2L1,MPDZ,NAE1,OSGIN2,MYRF,CACNB2,CH25H,CARS,RUNX1T1,KRIT1,USP6,TMEM257,LRBA,REPS2,DCLK1,CFL2,COPB2,NPIPA1,CHN1,PLEKHB1,JAM2,LSMEM2,LHX2,FBXO7,TJP2,QKI,NIPBL,FHL5,CNN3,CNR1,AKAP6,WHRN,COL9A3,ABI3BP,RCHY1,COX4I1,HS3ST5,CPS1,FAM171B,C2CD2,AKAP12,TRIM69,CSNK1G3,ATRNL1,PHF14,ST18,USP6NL,ARHGAP24,PHF19,LIN54,MATR3,DAPK1,BRINP1,SPATA2,DNAJC6,ZEB2,HP1BP3,FBXL5,CEP170,TMEM130,RHOBTB1,DLX1,USP3,DYNC1I1,CPEB2,SLC12A6,DPP6,ABI1,DSCAM,DTNA,ECM2,DNM1L,GOLT1B,EBF1,EDIL3,SNX29,RASGRP1,SEMA3D,KLHL5,FRY,PHF20L1,SUGP2,MRO,MBNL2,GOLGA7,EIF4G2,IRAK4,ELAVL2,EML1,C8orf37,EPHA5,KCNMB2,ENPP6,GPHN,SRRM1,EZH1,NRN1,F3,CLVS1,ABCA8,ZNF585B,ACSL4,ZIC4,ST3GAL6,GORAB,KIAA1109,FHL1,SUCO,CAP2,PCYOX1,ATP13A4,FLT1,ANKFY1,DCTN2,CAMKK2,STAU2,PNMA2,GAB1,CHL1,TRAF3IP2,CAB39,ILDR2,BRPF3,ARPP21,NCKAP1,ERAP1,GART,LRRC37A6P,GCNT2,ADAM28,GFRA2,PPARGC1A,MALT1,TCERG1,COPS8,GLDC,GLRB,ZNF638,CBX1,LUZP2,GNAS,FERMT2,GPM6B,NUDT21,EML4,PCLO,CNTRL,ATP2B1-AS1,GRB10,GRIA4,GRM3,COQ10A,AP4S1,PSIP1,MAP4K5,WIF1,UBE2QL1,ZHX1,NXPH2,MIER3,HLF,ZDHHC15,LRRC75A,SMAP1,HTR5A,IGFBP1,IGSF1,IL6ST,BRINP3,ZNF678,LRRTM3,NME9,ITGAV,JAK2,KCNA4,KCND2,IPO5,STXBP5,KTN1,LAMP2,PAXBP1,ARHGAP12,SMAD1,MAOB,MARK1,MARK3,MBP,MDM4,MEIS1,MEIS2,SRSF12,MITF,XRRA1,ERICH3,ZNF680,SESN3,ADAM22,NRBP2,CTNNA3,NCAM1,NELL2,NF1,SLCO1C1,OTOGL,NFE2L2,ALDH1L2,LRIT2,NTRK2,OPHN1,LOC100128398,CLDN11,P2RY1,GPR137C,ZDHHC22,PAH,GLIPR1L2,PDCD2,PRTG,PDGFRA,ENPP2,BEST3,OLA1,CDK14,PIK3C2A,PCDH18,HMGCLL1,PDZRN4,RC3H2,POU3F2,TATDN3,CRLS1,PPP3CB,KANSL1,PKIA,MAPK9,VPS13C,PTHLH,ELOVL2,TMEM260,ZSCAN32,PTPRG,PTPRN2,C1orf109,PTPRZ1,PTX3,TTC13,USP47,FAT4,DBX2,ZDHHC14,RET,FIGN,RFX4,KLHL11,SLC25A36,PBRM1,RNASEL,RPRD1A,CCDC82,SETD5,TMLHE,GSTCD,ELP2,SPIN3,ACER3,LRRK2,CLIP1,CCDC112,TRAPPC13,SALL1,MIR124-2HG,SEMA6D,ATXN7,SCN2A,LINC00461,TNFRSF19,SMPD3,SEC14L1,CASC3,RASA3,FERMT1,CPEB3,NTNG1,SHC4,MAGI3,FHOD3,ANKRD6,WDR37,DHX30,SEPHS1,SLC12A2,EFHD1,SLC20A2,SPHKAP,SMARCE1,RCOR3,MBD5,KIF13A,UNC80,USP33,SOX5,DOK5,SP4,MYCBP2,NPAS3,SPART,TAB2,ITPRID2,SSTR1,SS18,STAU1,ELOVL4,RGL1,SYT11,ZC3H4,ANKRD28,ANKRD12,MTCL1,PJA1,CAMTA1,CAMSAP2,FBXW11,EHBP1,ZEB1,RPGRIP1L,TCF12,WASHC4,SZT2,RALYL,PCDHB10,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,FAM200B,DICER1,SIRT1,ZFPM2,ITGB3BP,LEFTY2,AP4E1,ZMAT3,TMOD1,FAM124A,TP53BP2,ZNF384,RGMB,TRIO,AMACR,TRO,ANO5,TTC3,UGT8,SLAIN1,WRN,CLDND1,RICTOR,GUSBP1,SLC13A3,ZNF708,FMN2,NDRG4,ZNF138,TMEM237,POLR3H,ZSCAN26,DPYSL5,ANKS1B,SPIRE1,ZNF225,EMSY,MFF,RNF103,ADAMTS9,KCNAB1,FAM47E,MPPE1,WNK3,PDSS2,AMN1,PAK5,KAT6A,PHTF2,NLRP3,ZNF248,KLHDC1,FRMD6,IFT88,CBLN2,SLC4A10,SENP7" MicroRNA hsa-miR-641:mirSVR_highEffct hsa-miR-641:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-171 7.82E-168 1.04E-169 9.61E-169 452 1950 "RALGAPA1,SDE2,KCNH8,NCKAP5,ACTN1,CSMD3,KLHL32,ADD3,BRAP,PLEKHH1,KIAA1211,MTUS1,GPR158,HECW2,CC2D2A,TAOK1,ALCAM,ARHGAP20,AMPH,ZFAT,OGT,LRCH2,MAP4K3,PKP4,APBA2,GPAM,VAT1L,USP37,MIER1,TMEM263,TMEFF1,CADPS,LINC00173,ASPH,ZBTB10,DDX3Y,ATM,ATP1A2,ATP2B2,RNF182,BACH1,ZNF599,DST,CA8,THSD7A,KALRN,PTBP2,CAMK2G,HIP1R,ISPD,CBS,CLDN10,INA,LRBA,LRRFIP1,MAGI1,CDO1,CCPG1,SRSF11,SOCS6,CHM,CHN2,CASC2,SYNPR,NRXN1,NMT2,CLTA,QKI,SRP14-AS1,MAP4K4,FAM149A,AKAP6,COL4A5,SLC25A27,LETMD1,SLC4A8,ABI3BP,AHCTF1,NRG2,CNRIP1,CHD1L,CPS1,FAM171B,ANKRD44,NCOR1,TENM4,FEZ1,OSBPL3,CSNK1G3,PHACTR3,CNTNAP2,SLITRK5,DZIP3,PHF14,USP6NL,EDRF1,CCDC144A,HDAC9,ARHGAP32,GAPVD1,TOX,ZFYVE16,SPOCK2,PITPNC1,SPATA2,YTHDC1,DNAJC6,ZNF804A,ZEB2,MYEF2,CNIH3,MAGI2,ZC3H11A,PLPPR4,FAM107B,DMD,USP3,DMTF1,ABI1,PDCD6IP,DSCAM,DTNA,ECM2,DNAJB6,DNM1L,GOLT1B,E2F5,E2F6,EBF1,EDN1,FAM135B,RASGRP1,SEMA3D,PHF20L1,LPAR6,EIF4G2,EIF5,ELAVL2,RGS17,TMEM35A,EML1,EMX2,EPHB1,KCNMB2,GPHN,DNAJC27,F3,F8,FAM198B,TUBA1B,SCML2,GORAB,KIAA1109,FGF13,FGFR1,PRKAG2,MEX3B,HPCAL4,FOXG1,CAP2,SGIP1,NELFCD,TRMO,CELF1,STAU2,FYB1,STAG2,GABRG2,HBS1L,NCKAP1,KIAA1841,DNER,MYOZ2,WASHC2A,PCDH17,BRD8,GK,SPIN1,RAB30,GLS,MAP7D2,CNDP1,GPM6A,FUT10,CCDC184,STON1,EML4,SERP2,ATE1,GRM7,FAM19A2,MFSD2A,PSIP1,MAP4K5,ZHX1,PACSIN2,ARHGAP36,ELOVL5,ZDHHC15,DHX35,CELF5,SMAP1,HTR2A,LINC00667,USP54,BRINP3,DIPK1A,SLC35G1,METTL21A,OLFM3,KCNA4,KCNB1,KCND2,KCNH2,KCNK1,KCNK2,KIF5A,KIT,KLC1,LAMP2,LIG4,PAXBP1,SYTL4,VWA5A,NCOA7,SMAD9,MAP4,LYPLAL1,MAT2A,MBNL1,SRSF12,POC1B,AFDN,MOBP,CD200,ZNF680,BLOC1S2,ADAM22,MXI1,NAP1L1,NAP1L3,NDUFA5,NEFH,NEK1,NELL2,NF1,SLC11A2,NRCAM,HCN1,NTRK3,OLR1,OMG,PBX1,PCDH8,PCDH9,PCSK2,PDE3B,PDE4B,PDPK1,GNG2,BEST3,CDK14,PIK3C2A,CCSER2,SNX10,PLCL1,PLP1,PLXNB3,TRHDE,MAPKAP1,STRN3,LRP12,EXOSC10,SPATA6,EPB41L4B,TATDN3,PPP2R5C,PPP2R5E,PPP3CB,KANSL1,PKIA,PKN2,MAPK4,MAPK10,GRAMD1C,PRPH,RELN,GON4L,MDGA2,PIGG,CNTLN,PTHLH,PTK2,SPDL1,TMEM260,PTPRG,RIPOR1,CEP97,ZCWPW1,OXR1,VEPH1,RDX,RFX2,RFX3,RGS4,RGS7,SLC25A36,RNASEL,RPRD1A,ZFHX4,TMLHE,CARF,ROBO1,CCDC102B,ARMH4,BAALC,ATP8B4,GLDN,CLIP1,RTN1,ZNF331,RMI1,SATB1,SCN2B,FAM19A1,FNIP1,ELMOD1,SEC14L1,TRA2B,SH3GL2,CPEB3,CHD9,FBXO11,FNDC3A,CNKSR2,NUBPL,ABLIM3,FAM81A,EPN2,KANSL3,KDM4D,SEPHS1,RAB3GAP1,ARHGEF40,SLC14A1,ELMO2,SLC22A4,CXXC4,SORCS3,SMARCE1,RCOR3,SNRPN,PALLD,USP33,SON,MYT1L,ZCCHC24,BDP1,ZC3H13,KIF1B,RBM26,NPAS3,SPART,LMO3,SRPK2,ATP10B,NKAIN2,ERBIN,MAPK8IP3,ZSCAN29,ELOVL4,TTBK2,RGL1,DIP2A,ADHFE1,VPS13A,DNAJC9,PLCB1,SYN2,SYT1,TAC1,CAMTA1,CAMSAP2,ADGRL3,TCF7L2,ZEB1,WASHC4,WDR7,SYNE1,TMEM151B,PCDHB9,PCDHB3,SLC35G2,PCDHA1,TEK,ITGB3BP,AP4E1,TGFBR3,ZNF106,TJP1,ZFP91,ERCC6L2,PARD3,KAT6B,TPD52,NPL,TPM3,METTL3,SMUG1,RUNDC3B,STXBP4,TRPC1,TRPC3,TRPS1,ANKRD20A2,CLHC1,TMEFF2,CADM1,UBE3A,AMOT,UCHL1,DNAJC12,PLEKHH2,CLDND1,XRCC4,ZIC3,ZNF711,MICU3,ZNF32,KCNT2,EML6,SMARCAD1,SYNC,INTS3,LINC02210,STOX2,PRDM10,PCDH15,FIP1L1,PDSS2,FAM13C,AMN1,UBE3B,KAT6A,SMIM8,HNRNPA3,PHTF2,SNX14,FRMD6,NETO1,AP3B2,LAS1L" MicroRNA hsa-miR-199a-5p:mirSVR_lowEffct hsa-miR-199a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.62E-171 9.12E-168 1.20E-169 1.11E-168 438 1833 "TTYH1,DGCR6,ABR,ACHE,ACTN2,KDM5D,FAM43B,CSMD3,TMEM132B,ERMN,PLEKHH1,USP31,BEND6,SLC24A4,AP2A2,KCTD16,HACE1,TBC1D14,OSBPL8,CC2D2A,TAOK1,SEMA6A,ALCAM,ABCD2,ARHGAP20,SYT13,AMPD2,AMPD3,ANK2,SUGT1P4-STRA6LP-CCDC180,UPRT,APP,CDK10,TMEM263,TMEFF1,ARRB2,CADPS,MARK4,ASPH,BRINP2,ATP1B3,ZNF582,DPY19L3,ATP6V0A1,ADAM23,TTLL9,ADAM15,ADGRB2,BCHE,BCL2L2,BID,PROM1,KSR1,SYNJ1,ARHGEF7,MTMR2,BSN,WASF1,MYRF,BTRC,CA4,CA8,CACNB2,CACNB4,CALB1,KALRN,PTBP2,VSTM2A,CH25H,PRC1,CBLN1,CBR1,ZNF501,CCKBR,METTL6,AIFM1,LRBA,CDC42,CDH2,CDH8,LOC730101,DLGAP1,CLGN,CBARP,CHRM1,CHRNB2,KMT2C,RAB33A,SLC24A2,ABCG2,SULT4A1,SRP14-AS1,HECTD1,NIPBL,AKAP7,AKAP6,SLC4A8,SMARCAL1,MYRIP,ZNF385A,SLC35F1,PNKD,CREM,TENM4,SEC24C,ARHGEF10,PDE4DIP,RASGEF1C,KIAA0040,GREB1,NRSN1,PUM1,ST18,DCAF4,BOC,DCAF8,INTS1,DGKG,DAPK1,IP6K1,BRINP1,ARMCX4,HEPH,DDX46,PLPPR4,SNAP91,SRGAP3,TMCC2,ARNT2,EXOG,DMD,DNM1,DNAH9,NR1D2,DPH1,DPP6,DPYSL2,DRP2,GNE,DYRK1A,ABCC5,E2F5,EDIL3,EDNRA,EDNRB,HEYL,FRY,YAF2,SUGP2,KMT5B,IRAK4,ELAVL4,EIF1,EPB41L1,DMTN,LRRC17,CDKL3,DNAJC27,CLVS1,EFEMP1,FCGR1A,TOMM40L,FCGRT,KAT8,ZNF589,FGF11,PRKAG2,SUCO,MEX3B,PCYOX1,SYNCRIP,ANKFY1,AKAP3,JKAMP,POMT1,CINP,NPTN,ERGIC3,DACH2,AP4B1,NRG3,OGA,MEGF10,GABRA1,GAD2,HBS1L,BRPF3,ZMYND11,ARPP21,ZNF274,IP6K3,DISC1,SRRM4,GATM,ALDH1L1,WASHC2A,SESN1,MMADHC,USP19,GGT7,MALT1,TCERG1,COPS8,GLI2,MAP7D2,GNAS,NUDT21,GRB10,GRID1,GRM1,LINC00839,AP4S1,ADAMTS6,GYG1,WIF1,HPS5,NCKAP1L,MIER3,HLF,VSIG4,ELOVL5,HNMT,NEGR1,ICA1,LINC00667,ZNF546,GAREM2,SCIN,OLFM3,KCNC1,KCNJ3,KTN1,STMN1,HECTD2,MAP2,MAP4,MATN2,MBP,SYT9,ADAM11,LDLRAD3,PPM1L,POC1B,MITF,MN1,MPP2,RSPO2,MYCN,MYO9A,RTL5,NAP1L2,NEFM,NEK1,NEUROD1,NOVA1,SLC11A2,NTRK3,IGSF11,OCRL,ODF2,OMG,ZDHHC22,GLIPR1L2,PCMT1,PDE3A,PDE4D,PDGFRA,ENPP2,PFKFB2,PFKFB4,CDK14,PIK3R1,FAM218A,A2ML1,GPSM2,SLC25A23,PLXNB1,PURG,PMP22,ING3,SH3KBP1,FSD1,POU6F1,PPM1B,RASGEF1B,EPDR1,MAPK7,MAPK9,GRAMD1C,GON4L,MDGA2,WDR25,CNTLN,BDNF-AS,PTHLH,PTK2,STK32A,PTPRB,PTPRD,PTPRE,PTPRG,FAM120C,PTX3,ZNF615,TMEM255A,FAM66C,FAM184A,ROGDI,RASGRF1,DBX2,BSDC1,MORC4,GTDC1,RFX3,RFX4,SLC25A36,PBRM1,SUGCT,CARF,CCDC25,TMEM100,EPHA10,RPL15,UEVLD,MAP6D1,RPS20,TRAPPC13,DGLUCY,ATXN7,HOGA1,SCN3A,TNFRSF19,ASIC4,PPP1R9A,R3HDM2,CNKSR2,BTBD3,ZNF430,RAB3GAP1,SLC12A2,NAPB,SCMH1,SLC22A4,NAXD,SMARCE1,RIMS1,SNRPN,PALLD,FAM126B,MYO16,PDZD2,SOX5,SP4,MYCBP2,KDM4C,SPTB,ATP10B,STOX1,SMOC1,CEP68,GANAB,SYT11,MLC1,ZFR2,VPS13A,TMEM150C,ARC,SYN2,SYPL1,TAC1,TACC1,TAL1,FAM208A,FBXW11,TMEM136,KLHL4,EHBP1,ZFP90,TPCN2,TRIM2,DOCK9,TMEM151B,FAM189A1,SLC19A3,AKNA,HIF3A,TEK,ATP13A2,AP4E1,GPR161,HHIP,SLC44A1,MTMR14,TMEM9,BEX4,RIMBP2,TNR,TPM1,RGMB,PDSS1,STXBP4,TRPS1,TTC3,SGK3,CADM1,FAM155A,SLAIN1,ZNF709,LAT2,ZNF781,NSD2,GUSBP1,ZNF28,ZNF70,NDRG4,MKRN3,CELF4,SMARCAD1,UPF3A,SLC30A4,MAP3K12,PRDM2,SLC38A1,RGMA,GDPD5,LINC02210,PRDM10,RNF103,SCG2,SLC17A6,RGS7BP,FZD3,NUP214,ADAMTSL3,JMJD1C,FXR1,NETO2,JPH3" MicroRNA hsa-miR-19a:mirSVR_highEffct hsa-miR-19a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.80E-171 1.01E-167 1.31E-169 1.21E-168 410 1606 "ABR,NCKAP5,ACTN1,CSMD3,GRAMD1B,KIAA1211,ESYT2,BEND6,DPY19L2P4,GPR158,HECW2,WDR35,SRPX,PCDH10,FAM135A,CDC42BPA,LRCH2,MAP4K3,PHF12,ANXA7,APAF1,USP37,SHTN1,MIER1,TMEM263,LINC00173,CDK13,STK33,CAPRIN2,ZBTB10,CCAR2,DDX3Y,ATP1A2,STX16,ZNF583,NOL4,ATP6V0A1,BARD1,NRP2,ST3GAL5,JAZF1,C5,IL33,CA4,THSD7A,CALM1,KALRN,SYT6,CAST,RUNX1T1,PRC1,USP6,INA,CBFA2T2,SEPT7,ZMYM4,LRRFIP1,EVI5L,TIGD7,CCPG1,CFL2,SRSF11,SYNPR,ZFYVE9,PLAA,NRXN1,CLTC,QKI,NIPBL,CNGA3,FHL5,CNTFR,AKAP7,ARMC8,FAM149A,BTF3L4,LETMD1,SLC4A7,COX4I1,AHCTF1,SMARCAL1,ACBD5,ZNF521,HS3ST5,SLC35F1,CLOCK,GDA,CS,CSF1,LRIG1,MICAL2,ATRNL1,CHD5,SOCS5,PDE4DIP,APPL1,PHF14,CFAP61,PPP6R2,DCAF8,LONRF1,DAPK1,IP6K1,GIT2,DBN1,PITPNC1,ZNF804A,CEP170,MAGI2,ZC3H11A,DDX46,SACS,G3BP2,WDR20,DLX1,USP3,CPEB2,DSCAM,ARRDC4,DTNA,ECM2,DYRK1A,ABCC9,AASDH,EBF1,EDIL3,EDNRB,SGK2,HIPK3,YAF2,FAM13A,PHF20L1,EGR3,PLXNC1,EIF4G2,CERCAM,ELAVL4,EML1,EMX2,OLIG2,EPHA5,ENPP6,NCALD,NRN1,F3,ABCA8,WAC,ACSL4,CORO2B,TESK2,FER,MED12L,OLFM1,FGF12,FGF13,CAMSAP1,SUCO,FOXF2,SYNCRIP,FLNC,FLT1,NBEA,NPTN,ATP2C1,NSG1,TBR1,FYB1,GABBR1,CAB39,GAD2,HBS1L,ZMYND11,SIGLEC8,ARFIP1,ADAM28,MALT1,CRCP,GLS,CBX1,MAP7D2,INSM2,FERMT2,PRUNE2,GPR34,RAPGEF4,GRB10,GRM7,KAT7,MFSD2A,ELOVL5,HTR5A,ZIC5,ZNF678,DIPK1A,ZNF385B,KCNA4,KCNC2,KCND2,KCNJ3,KCNK2,CREG2,KIF5C,INSYN2,ARHGAP12,MATN2,MATN3,MBNL1,MDM4,MID1,MOG,CD200,ZNF680,BLOC1S2,BCO1,MSRA,N6AMT1,MYCN,MYO9A,ZNF862,NAP1L2,NCF2,NDUFA5,IDNK,NEUROD1,NME4,CNOT4,TBC1D25,OCRL,OMG,OXTR,PCSK5,PDE1C,PDE3B,PDE4D,SLC10A4,CDK14,CCSER2,JAKMIP1,MAPKAP1,STRN3,LRP12,SCHIP1,TNPO2,SH3KBP1,POLR2F,POU3F2,MINDY2,PPM1B,PPP2R5E,PPP3CB,PRKACB,HYDIN,RELN,PSD,PLPPR1,MTMR10,ZIK1,PTPRD,CASTOR1,PTPRG,TMEM255A,RAD51D,ATG16L1,RASGRF2,RBBP8,RET,GTDC1,RFX4,SEC61A2,SLC25A36,RPRD1A,SETD5,GSTCD,ROBO2,PRR5L,STK32B,LRRK2,ABCA11P,CLIP1,RTN1,ATXN7,LRFN5,SCN3A,TNFRSF19,SEC14L1,SOX6,SGK1,ITSN1,SH3GL2,DOCK10,FNDC3A,R3HDM2,ST6GAL1,SYBU,NLGN1,BTBD3,WDR47,RUFY2,SLC6A8,SLC8A1,RAB3GAP1,CCDC88A,SLC14A1,BTBD7,SPHKAP,RCOR3,LIMCH1,SNAP25,KIF13A,SNRPN,UNC80,USP33,SON,MYT1L,TRERF1,SOX2,SOX5,ZC3H13,CDK19,SPART,TAB2,TROVE2,POGZ,SMOC1,SSTR2,MPRIP,RGL1,FAM168A,C3orf70,PLCB1,SYN1,ARC,SYN2,SYPL1,SYT1,KAZN,MTCL1,CAMTA1,CAMSAP2,ALG1,IQCE,FBXW11,ATMIN,EHBP1,SIN3B,DMXL2,TRIM2,TCF12,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,DICER1,ZFPM2,TGFBR3,SLC44A1,TK2,TLL2,ZFP91,HEY2,CSMD1,PARD3,NPL,WBP2,STXBP4,TRPC3,TSN,TSC1,TUB,CLHC1,TMEFF2,FAM155A,SLAIN1,USP1,RICTOR,XRCC4,ZBTB14,ZNF711,KCNT2,ZNF74,PLPP4,CELF4,ANKS1B,FTSJ1,PLPPR5,WNK1,PMEPA1,MAP3K12,MFF,STOX2,PRDM10,PCDH15,NAV3,FIP1L1,WNK3,RGS7BP,FAM13C,ST7,PAK5,PHTF2,FXR1,FRMD6,CBLN2,GAN" MicroRNA hsa-miR-519a:mirSVR_highEffct hsa-miR-519a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.48E-171 1.95E-167 2.51E-169 2.31E-168 387 1430 "KCNH8,NCKAP5,ADCY6,GALNT13,KIDINS220,SLC24A4,ZNF608,GPR158,HFM1,LRRC7,SPARCL1,SRPX,ABCD2,ARHGAP20,MRTFA,OGT,LRCH2,SEMA7A,EP400,USP28,API5,SHTN1,LINC00173,STK33,CAPRIN2,RASL11B,ATM,SLC4A4,ATP2A2,ATP2B1,ZNF583,B3GALT2,NOL4,NRP2,DST,SYNJ1,SCAPER,C5,MYRF,HIP1R,MAP7,PRC1,USP6,LRRFIP1,TIGD7,CFL2,CHN2,ZFYVE9,ABCG2,IGLON5,BTF3L4,SLC4A8,RCHY1,AHCTF1,HS3ST5,FAM171B,PREPL,CREM,ENTPD4,CRY2,ANKRD44,GDA,CSF1,LRIG1,SIPA1L1,CHD5,PITPNM3,UBXN2A,PHF14,NRSN1,PPP6R2,CCDC144A,CYBB,BOC,KATNAL2,ARHGAP24,DCAF8,ZFYVE16,MAML1,PABPC5,MYEF2,FBXL5,PLPPR4,SACS,WDR20,DMD,USP3,CPEB2,DPYSL2,DNAJB6,DYRK1A,DNM1L,ABCC9,EBF1,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,CERCAM,C3orf18,CALCRL,CEP85L,RASL12,EZH1,F3,ACSL4,TAOK3,CEP78,TESK2,SLC9B2,PRKAG2,MEX3B,FOXG1,FOXF2,RGPD5,JKAMP,NBEA,UFM1,TPK1,ATP2C1,GAB1,GABBR1,GABRA1,GAD2,B4GALNT1,ARPP21,ERAP1,DISC1,MYOZ2,SULT1C4,ZNF276,GLS,TOX3,ZNF638,LUZP2,GNAL,RAPGEF4,GRB10,DIDO1,GRIA4,ADAMTS8,GRM5,GRM7,CIT,LINC00839,RNF165,RABL2A,PSIP1,GUCY1B1,MAEL,HAS2,HPS5,NXPH2,FRMD3,MIER3,TLX1,IRF8,DOCK7,LRRCC1,ZNF678,DIPK1A,JAK1,KCND2,KCNJ10,KCNK1,KCNN2,CREG2,KIF5A,KIF5C,LIG4,FGFBP3,ARHGAP12,C2orf80,SMAD9,PIK3AP1,MAP4,MARK1,MATN3,MBNL1,MDM4,LRP1B,MID1,MITF,XRRA1,MOG,ERICH3,BCO1,MSR1,RSPO2,LAYN,MYT1,NACA,NELL1,NELL2,NEUROD1,NF1,ALDH1L2,NNAT,CNOT4,SLC11A2,OCRL,GPR137C,CNTN3,PDE3B,PDGFRA,GNG2,BEST3,FAM218A,CCSER2,TMEM38A,JAKMIP1,SCHIP1,PMS2,EPB41L4B,PPM1B,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PKIA,MASP1,PSD,VPS13C,APTX,SNRK,PIGG,CNTLN,PTHLH,PTPRB,ACSM5,ZSCAN2,QDPR,RAB5B,PID1,CEP97,SLC25A48,USP47,ATG16L1,OXR1,ARID4A,RBBP6,ZDHHC14,ZYG11B,TRIM68,RET,RFX3,RFX5,SLC25A36,RNASEL,ZFHX4,CCDC82,SETD5,RAVER2,PNMA8A,ROBO1,RORB,UEVLD,ZNF671,CNTNAP3,RTN1,RYR3,SALL1,CSRNP3,HOGA1,SCN3A,FAM19A1,PRCD,SCP2,HSPA4L,ITSN1,PPP1R9A,ARX,KIF16B,CPEB3,SHC4,CHD9,SLITRK3,SYBU,PAAF1,FAM81A,RUFY2,LRRC55,RAB3GAP1,CCDC88A,BTBD7,NAXD,RCOR3,ANKRD36,KIF13A,CMTR2,SNRPN,TMCC1,USP33,MYT1L,TRERF1,SOX5,DOK5,HECW1,TEX2,IQSEC2,SPART,C11orf87,CLASP2,TROVE2,POGZ,ITPRID2,SMOC1,LARP4,ERBIN,ADHFE1,NECAB1,PLCB1,SYT1,ANKRD12,PJA1,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,SATB2,ZFP90,USP22,RALYL,PCDHB10,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,ZFPM2,TGFBR3,AKTIP,SLC44A1,THRA,TLR4,HEY2,R3HDM1,STXBP4,TRPC1,TSC1,UBC,FAM155A,UBE3A,SLAIN1,PITPNB,FLRT2,VLDLR,TBC1D15,NSD2,XPO1,PCDH20,ZBTB14,ZNF711,ZNF45,ZNF74,MKRN3,TCEAL7,REEP1,FSTL5,ANKS1B,CA10,MAP3K12,MFF,CSDE1,SNX27,CAB39L,FAM47E,WNK3,SLC17A6,PLSCR4,RGS7BP,SMIM8,PHTF2,CASC15,SSPN,FXR1,FRMD6,NETO2,SENP7" MicroRNA hsa-let-7f-2*:mirSVR_highEffct hsa-let-7f-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-170 1.19E-166 1.51E-168 1.39E-167 425 1737 "RALGAPA1,ASIC1,ACHE,CLK4,CSMD2,NDRG3,CCDC85A,AXIN2,SORCS1,PLEKHH1,PWWP2A,PTCHD1,ADRB2,NLGN4X,ZNF608,MTUS1,KLHL13,KIAA1324,CC2D2A,SPARCL1,ALCAM,ZFAT,DPP10,ANK3,PHF12,APBA2,UPRT,ALS2,APP,LGR5,MIER1,RGS20,ASPH,RASL11B,ATP1A2,ATP1B3,RNF182,ALDH7A1,B3GALT2,NOL4,DOCK11,BACH1,SEC11C,BMP7,CDK5R1,DST,NAE1,MTMR2,C5,IL33,CA8,CACNB2,KALRN,PTBP2,CAMK2D,CH25H,PRC1,KRIT1,USP6,CBFA2T2,TMEM257,C1orf52,DGKI,LRRFIP1,CFL2,SRSF11,SOCS6,NDST3,LHX2,KMT2C,RAB33A,C4orf33,QKI,HECTD1,CNR1,ARMC8,AKAP6,RTTN,MFSD4A,SLC35F1,ENTPD4,RBM39,CS,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,SUSD5,VCAN,PDE4DIP,PHACTR3,PPP1R16B,NRSN1,USP6NL,GPRASP1,RIPOR2,FRMPD4,TOX,MAML1,DGKB,DAPK1,BRINP1,ZNF804A,TIAM2,KIAA0319,DDX46,SNAP91,NTM,WDR20,DLG3,GRIN3A,RAB39B,NR1D2,CDON,CPEB2,CASP8AP2,DRD1,PDCD6IP,DTNA,ABCC5,E2F5,E2F6,AASDH,FAM135B,EDN3,EDNRA,ANKRD46,SEMA3D,OPTN,RBM12,PHF20L1,MBNL2,GOLGA7,TENM1,ELAVL2,PLEKHA1,EML1,CALCRL,LRRC17,EPHA5,GPHN,MRPL37,CDKL3,ETV1,EYA1,F8,ABCA8,FAM198B,RPS6KC1,ST3GAL6,FGF13,FGFR3,PRKAG2,SUCO,UBE2E3,SYNCRIP,RGPD5,PSD2,SLC37A3,HVCN1,STAMBP,TPK1,CAMKK2,ATP6V1H,ATP2C1,KHDRBS3,STAG2,GABRA1,ZNF44,FAM120B,ZNF234,NCKAP1,IQGAP2,ERAP1,C15orf41,GCNT2,MSTN,ARFIP1,PCDH17,PPARGC1A,GLRB,ZNF638,MAP7D2,INSM2,LUZP2,GNAO1,FERMT2,GPT2,ADGRA3,PRUNE2,GPR22,EML4,GRIA4,GRM1,GRM3,GRM7,KIF3A,LINC01551,AP4S1,GYG1,RASSF8,HAS2,ZHX1,LINC01102,MIER3,HMGCR,ZDHHC15,TCEAL6,MSL1,ZIC5,RBPJ,INPP1,RIPPLY2,INPP5B,INSM1,KCNC1,KCNC2,KIF5A,KIT,KLC1,STXBP5,STMN1,PAXBP1,LMO1,HECTD2,PIK3AP1,MAP2,MARK1,MAT2A,MBNL1,LDLRAD3,LRP1B,SRSF12,MITF,MN1,ZNF680,JAKMIP3,RSPO2,MYBPC1,MYCN,MYO9A,NASP,NDUFA5,NEUROD1,ALDH1L2,NODAL,CNOT4,NOVA2,NPTX1,NRCAM,CHAMP1,LOC100128398,PAH,TREM2,CNTN3,PCDH8,PCSK2,PDE2A,PDE3A,BEST3,NLGN3,FAM218A,CCSER2,FTO,STRN3,RC3H2,PSAT1,SCHIP1,PRRX1,ING3,IRX1,PPM1B,PPP2R2B,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PRKACB,CEP41,MAPK10,GRAMD1C,MASP1,LRRC49,CNTLN,ANKHD1,BDNF-AS,TMEM260,TMEM255A,ZNF493,OXR1,ARID4A,DBX2,RBBP6,KHDRBS2,MSANTD2,SLC6A15,RET,MORC4,RFX4,ARHGEF10L,RNF220,PBRM1,RPRD1A,ZFHX4,DCUN1D2,CARF,GSTCD,ROBO1,ROBO2,ELP2,PTGR2,ABCA11P,KCNIP3,ZNF568,SALL1,SATB1,ATXN2,LRRTM4,FNIP1,ELMOD1,SFPQ,SUPT20H,SH3GL3,NTNG1,SHC4,MAGI3,CNKSR2,WDR37,SLC1A6,FAM81A,EPN2,SLC8A1,SLC14A1,SMARCA4,SMARCE1,RIMS1,SNCA,MBD5,KIF13A,TMCC1,MYO16,FAM219A,SON,TRERF1,SOX2,ZCCHC24,MYCBP2,RBM26,LMO3,C11orf87,PBLD,ITPRID2,SMOC1,NKAIN2,ERBIN,NXT2,STAU1,RGL1,DIP2A,STXBP1,NECAB1,RHBDL3,VPS13A,SYN2,COBL,ANKRD28,ANKRD12,DDHD2,CAMTA1,FAM208A,MGRN1,CUX2,TCF7L2,WDR7,RALYL,PCDHB9,USP32P1,FRYL,SIK3,TEK,ZFPM2,ITGB3BP,SLC44A1,FBXL16,TIAM1,TLL2,TLR4,BEX4,TPD52,NPL,PRMT8,STXBP4,ANKRD20A2,SSBP2,TMEFF2,CADM1,USP1,TBC1D15,WIPF1,ZNF781,KLC2,GUSBP1,SLC13A3,ETNPPL,XRCC4,PCDH20,ZFP37,ZIC3,FMN2,ZNF138,ZBTB38,FSTL5,CADM2,PCDH15,NAV3,SLC17A6,RGS7BP,GOPC,FAM13C,DOCK8,RTN4,SMIM8,ZNF248,PIANP,FXR1" MicroRNA hsa-miR-19b:mirSVR_highEffct hsa-miR-19b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.59E-170 2.01E-166 2.52E-168 2.32E-167 396 1508 "ABR,ABHD6,NCKAP5,ACTN1,CSMD3,GRAMD1B,KIAA1211,DPY19L2P4,GPR158,HECW2,WDR35,SRPX,PCDH10,FAM135A,CDC42BPA,LRCH2,MAP4K3,PHF12,ANXA7,APAF1,APBA2,USP37,SHTN1,MIER1,TMEM263,LINC00173,CDK13,STK33,CAPRIN2,ZBTB10,CCAR2,DDX3Y,ATP1A2,STX16,ZNF583,NOL4,ATP6V0A1,BARD1,NRP2,ST3GAL5,JAZF1,C5,IL33,CA4,THSD7A,CALM1,KALRN,SYT6,CAST,RUNX1T1,PRC1,USP6,CBFA2T2,SEPT7,ZMYM4,LRRFIP1,EVI5L,TIGD7,CCPG1,CFL2,SRSF11,ZFYVE9,PLAA,CLTC,QKI,NIPBL,CNGA3,FHL5,CNTFR,AKAP7,ARMC8,FAM149A,BTF3L4,LETMD1,SLC4A7,COX4I1,SMARCAL1,ACBD5,ZNF521,IGDCC3,HS3ST5,SLC35F1,CLOCK,GDA,CS,SNCAIP,CSF1,LRIG1,MICAL2,ATRNL1,SOCS5,PDE4DIP,ERC2,APPL1,PHF14,PPP6R2,DCAF8,LONRF1,DAPK1,IP6K1,GIT2,DBN1,PITPNC1,ZNF804A,CEP170,MAGI2,DDX46,RHOBTB1,SACS,G3BP2,WDR20,DLX1,USP3,CPEB2,DSCAM,ARRDC4,DTNA,ECM2,DYRK1A,ABCC9,AASDH,EBF1,EDIL3,EDNRB,HIPK3,YAF2,FAM13A,EGR3,PLXNC1,EIF4G2,CERCAM,ELAVL4,EML1,EMX2,EPHA5,ENPP6,NCALD,F3,ABCA8,WAC,ACSL4,CORO2B,TESK2,FER,MED12L,OLFM1,FGF13,CAMSAP1,SUCO,FOXF2,SYNCRIP,FLNC,FLT1,NBEA,NPTN,ATP2C1,NSG1,TBR1,FYB1,GABBR1,CAB39,GAD2,HBS1L,ZMYND11,SIGLEC8,ARFIP1,ADAM28,MALT1,CRCP,GLS,CBX1,INSM2,FERMT2,PRUNE2,GPR34,RAPGEF4,GRB10,GRM7,KAT7,MFSD2A,ELOVL5,HTR5A,ZIC5,ZNF678,DIPK1A,ZNF385B,KCNA4,KCNC2,KCND2,KCNJ3,KCNK2,CREG2,INSYN2,ARHGAP12,MATN2,MATN3,MBNL1,MDM4,MID1,MOG,CD200,ZNF680,BLOC1S2,BCO1,MSRA,N6AMT1,MYCN,MYO9A,ZNF862,NAP1L2,NDUFA5,IDNK,NEUROD1,NME4,CNOT4,TBC1D25,OCRL,OMG,OXTR,PCSK5,PDE1C,PDE3B,PDE4D,SLC10A4,CDK14,CCSER2,PLCL1,JAKMIP1,MAPKAP1,STRN3,LRP12,SCHIP1,TNPO2,SH3KBP1,POLR2F,POU3F2,MINDY2,PPM1B,PPP2R5E,PPP3CB,PRKACB,RELN,PSD,PLPPR1,MTMR10,TMEM260,PTPRD,CASTOR1,PTPRG,ACSM5,RAD51D,ATG16L1,RASGRF2,RBBP8,RET,GTDC1,RFX4,SEC61A2,SLC25A36,RPRD1A,SETD5,GSTCD,ROBO2,PRR5L,STK32B,LRRK2,ABCA11P,CLIP1,RTN1,ATXN7,SCN3A,SCP2,TNFRSF19,SEC14L1,SOX6,SGK1,ITSN1,SH3GL2,DOCK10,FNDC3A,R3HDM2,ST6GAL1,SYBU,BTBD3,WDR47,RUFY2,SLC6A8,SLC8A1,RAB3GAP1,CCDC88A,SLC14A1,BTBD7,SPHKAP,RCOR3,LIMCH1,SNAP25,KIF13A,SNRPN,UNC80,USP33,SON,MYT1L,TRERF1,SOX2,SOX5,ZC3H13,CDK19,SPART,TAB2,TROVE2,POGZ,SMOC1,SSTR2,MPRIP,RGL1,FAM168A,C3orf70,PLCB1,SYN1,ARC,SYN2,SYPL1,SYT1,KAZN,MTCL1,CAMTA1,CAMSAP2,ALG1,IQCE,FBXW11,ATMIN,EHBP1,SIN3B,DMXL2,TRIM2,TCF12,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,DICER1,ZFPM2,TGFBR3,TK2,TLL2,ZFP91,HEY2,CSMD1,NPL,WBP2,STXBP4,TRPC1,TRPC3,TSN,TSC1,TUB,CLHC1,TMEFF2,SGK3,FAM155A,SLAIN1,RICTOR,XRCC4,ZBTB14,ZIC1,ZNF711,FMN2,ZNF74,PLPP4,CELF4,ANKS1B,FTSJ1,WNK1,PMEPA1,MAP3K12,MFF,STOX2,PRDM10,PCDH15,NAV3,WNK3,RGS7BP,FAM13C,ST7,PAK5,PHTF2,FXR1,FRMD6,CBLN2,SENP7" MicroRNA hsa-miR-455-3p:mirSVR_lowEffct hsa-miR-455-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-169 9.31E-166 1.14E-167 1.05E-166 420 1705 "TTYH1,ASPHD1,CLK4,NBAT1,SLC25A25,CSMD3,GALNT16,ADCY6,ADD1,PWWP2A,KIAA1211,SNX30,ESYT2,AP2A1,AP2A2,OSBPL1A,OSBPL6,OSBPL8,CC2D2A,AK2,SEMA6A,ABCD2,GOLGA7B,FAM135A,SYT13,MRTFA,ZNF687,AMPD2,ANK3,LCORL,SUGT1P4-STRA6LP-CCDC180,APBA2,GPAM,FAM131A,TNRC6C,PPFIA3,SLC7A14,CASK,CDK13,PDE8B,MARK4,PCDHGB4,NUMB,RASL11B,TMEM108,EIF4G3,ATP2B3,ALDH7A1,ADAM23,TTLL9,ADAM15,SNAI3-AS1,ADGRB3,LINC00847,BBS2,RGS9,BCL2L2,ARHGEF7,BTK,CA4,CACNB2,PTBP2,CAMK2A,CAMK2D,CARS,CCKBR,METTL6,MTMR7,SCARB1,SYNGR3,CD38,REPS2,CDH2,ARHGAP33,LRRFIP1,UBE2L6,CACNA2D2,ASIC3,CHN2,SYNPR,JAM2,RAB28,NRXN3,KIAA1549L,NRXN1,NIPBL,CNTN1,COL4A5,BTF3L4,SLC4A7,TBPL1,COX4I1,AHCTF1,BAG4,SLC35F1,SEC31B,AKAP12,CRY2,HINFP,NCOR2,GDA,TENM4,FEZ1,MICAL2,CSNK1E,VAC14-AS1,PPP6R2,ARHGAP32,KATNAL2,DCAF8,CENPL,EARS2,ZNF337,DAPK1,SPOCK2,DNAL1,ARMCX4,ARMCX2,SPATA2,SMG7,SV2B,G3BP2,CHRDL1,DLG4,DMD,DNM1,DNAH9,CD99L2,TRAPPC9,CDON,DRP2,PDCD6IP,E2F5,AASDH,EDNRB,SGK2,HIPK3,HEYL,RBM12,YAF2,PHF20L1,SUGP2,KCTD3,SORBS3,ELAVL4,TUBD1,KCNMB2,ANKRD13B,RABEPK,SPEG,MRPL37,CDKL3,CLVS1,FAM198B,DLC1,FCGRT,FDFT1,TESK2,KAT8,PPP1R1B,ZNF589,SEC24B,OLFM1,FGFR3,CAMSAP1,MEX3B,WDR83,SORBS1,SPECC1,TPK1,CAMKK2,ZNF605,B3GAT1,SARAF,OGA,MEGF10,GABRA3,ILDR2,FAM184B,GALR1,IP6K3,LRRC37A6P,ALDH1L1,GFAP,ADAM28,GGTA1P,PPARGC1A,MALT1,RUNDC3A,GLDC,STARD3,LUZP2,LOXL3,GNAO1,GNAS,FERMT2,ADGRA3,GPD2,LILRA1,STON1,NUDT21,RAPGEF4,GRB10,DIDO1,GRIA4,PLCD4,ADAMTS8,GRM1,GRM3,BTN2A1,KIF3A,MFSD2A,DDX19B,HMGB1,HNMT,NEGR1,HSF2,LRRC75A,LINC00667,NKD1,GAREM2,TJAP1,ITPKB,KCND1,KCNJ3,KCNJ9,KCNK2,KCNN1,LINC00634,KIT,A1BG-AS1,PAXBP1,LDLRAD3,MDM4,MEIS1,MEIS2,SRSF12,KITLG,MOBP,CD200,STK32C,BLOC1S2,RSPO2,MYO6,RTL5,FXYD6,NEFM,NEK1,NF1,NPTX2,NTRK2,NTRK3,NUMA1,TREM2,SNTG1,PCDHGC3,PCDH9,PCMT1,PIRT,GPR85,GNG2,ZDHHC8,NLE1,PNMA3,SCHIP1,PRRX1,PPP2R5C,PPP3CB,NKAIN4,RANBP3L,PRKAB2,PKIA,PRKCG,DCHS2,BCAS3,GDPD2,QRICH1,PIGG,PLPPR1,UHRF1BP1,PTHLH,PTN,TMEM260,PTPRB,OCIAD1,PTPRD,PTPRG,PTX3,TUG1,USP47,RAD51D,IQSEC3,FAT4,RASGRF1,ARID4A,ZYG11B,TRIM68,FIGN,RGS10,KLHL11,SEC61A2,RNASEL,SETD5,ARMC5,ROBO1,RPE65,NEK11,ARMH4,SPIN3,KCNIP1,FAM182A,MAPK12,LRRTM4,PRCD,ZNF821,FOXRED1,FAM102A,FERMT1,SHC4,R3HDM2,DZIP1,NUBPL,ZNF365,SLC1A3,SLC8A1,SHANK2,ELMO2,SMARCE1,MBD5,UNC80,FAM219A,TRERF1,GLT8D1,ZNF621,COLGALT2,ITPRID2,STOX1,SSPO,ZSCAN29,NEK4,SULF2,STXBP1,NSFL1C,FGD4,SYN2,TAC3,PJA1,PDLIM2,TCF4,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,DOCK9,PSD3,ARHGEF12,FRYL,PMS2CL,DICER1-AS1,CRB1,GALNT17,HEY1,DDHD1,ERCC6L2,TMPO,PIK3R5,WBP2,PRMT8,ELP5,ZMYND8,RUSC1,TSN,TSC1,TTTY15,ZKSCAN5,FLRT2,VAV1,VLDLR,VSNL1,RICTOR,GUSBP1,ETNPPL,SLC47A2,ZIC1,ZNF24,ZNF45,ATP6V0E2,ZBTB16,ZNF154,REEP1,EML6,PLPPR5,UPF3A,INTS3,ZXDA,NT5M,LINC02210,PRDM8,RNF103,VPS35L,NAV3,CAB39L,FBXO36,CASC15,MSRB3,NETO1,LAS1L,SPATA13" MicroRNA hsa-miR-376c:mirSVR_lowEffct hsa-miR-376c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-169 9.31E-166 1.14E-167 1.05E-166 420 1705 "SDE2,ASIC1,CSMD3,TMEM132B,DSCAML1,ADCY6,SLC12A5,SORCS1,SLC24A4,ZNF608,CASKIN1,OSBPL1A,OSBPL8,CC2D2A,HFM1,PCDH10,AMPH,ANK1,PPFIA1,APC,UPRT,ALS2,FAM131A,PPFIA3,USP37,PPP4R4,CASK,MARK4,RASL11B,TMEM108,SLC4A4,ATP1B3,ATP2A2,TTLL9,BACH1,BARD1,BCL7A,DCAF5,DST,FUBP1,IL33,LDLRAD4,CACNB4,ISPD,RUNX1T1,ZNF501,CCNH,SLC16A4,AIFM1,REPS2,CDH2,DCLK1,LRRFIP1,CDH18,CDO1,CIART,FOXN3,CHM,CHN1,CNOT8,LHX2,RAB28,NRXN3,ZFYVE9,TMEM59L,FBXO7,SRP14-AS1,HECTD1,NIPBL,CNN3,ABI3BP,ACBD5,MYRIP,ZFP28,SLC35F1,C2CD2,RBM39,AKAP12,HAPLN1,ANKRD44,CLIP3,NCAN,SLITRK5,DZIP3,APPL1,RIMS2,USP6NL,NOS1AP,KIAA0408,ARHGAP32,ZFYVE16,LONRF1,RIMS3,KIAA0586,DGKB,DAPK1,TOMM20,DCC,ELMSAN1,ZNF804A,C8orf34,ZEB2,ZBTB24,HP1BP3,COPS7A,CEP170,SRGAP3,G3BP2,WDR20,ZNF582-AS1,GRIN3A,DMD,NR1D2,DRD1,ECM2,ABCC5,FAM135B,EDNRA,TMTC1,SH3GLB1,CELSR3,MBNL2,KMT5B,PLEKHA1,RGS17,CALCRL,PAN3,DCTN4,EPB41L2,KCNMB2,RABEPK,SRRM1,NCALD,VPS26C,EXTL2,KATNAL1,F3,ZNF461,EFEMP1,FCGR1A,CEP78,FKTN,FECH,SEC24B,KIAA1109,FGF12,POLK,MEX3B,CAP2,SYNCRIP,FLT1,ANKFY1,TRIM16,NPTN,ATP2C1,KHDRBS3,CELF1,ST6GALNAC3,MSANTD4,OGA,FYN,GABRG1,BRPF3,GALC,GALR1,NCKAP1,IQGAP2,DISC1,CPLX2,KIAA1841,IGSF5,ALDH1L1,CYP46A1,MMADHC,TCERG1,PCDH11X,LUZP2,GNAO1,FERMT2,ADGRA3,DIPK1C,LILRA2,GPR12,EML4,RFFL,GRIK2,SERP2,GRIN1,ATE1,GRM5,ZNF496,FAM19A2,ZBTB49,AP4S1,CELF3,HAS2,ZHX1,NXPH2,PTGDR2,PACSIN2,FRMD3,BACH2,HMGB1,SYNPO,AGBL5,TLX1,ZDHHC15,AGFG1,EID2B,IGFBP1,IL12A,ZNF385B,KCNA2,KCNA4,KCNC2,KCNF1,KCNJ10,CREG2,KIF5A,STXBP5,LIG4,PAXBP1,SMAD1,MAP6,LDLRAD3,LRP1B,KCTD6,MID1,MMP16,ERICH3,ADAM22,SCG3,MYO6,MYO9A,NEXMIF,NEUROD2,NF1,NFE2L2,ALDH1L2,NHLH1,CLEC9A,SMIM11A,NTRK2,CHAMP1,OMG,OPA1,PAX6,PCDH8,PDE4B,TMOD2,OLA1,SERPINE2,ANLN,A2ML1,CCSER2,XRN1,GPSM2,PCDH18,PDZRN4,PMP22,STRN3,LRP12,SCHIP1,PRRX1,SDK2,SPATA6,FAT3,POU3F2,PPARA,MED1,PPM1B,PPP2R5C,PPP2R5E,PKIA,HYDIN,RELN,VPS13C,LRRC49,CNTLN,PTCH1,PTHLH,SPDL1,PTN,PTPRB,PTPRD,PTPRG,PTPRZ1,PEX5,PID1,ZNF793,FAM184A,NWD1,DBX2,KHDRBS2,GAL3ST4,RET,REV3L,GTDC1,UBR7,RGS4,RGS7,RIC8B,LGI2,ZNF532,ALG9,CARF,CYB561D1,CCDC25,CCDC102B,TMEM100,NEK11,FBXW7,LRRK2,ATAT1,CLIP1,SEMA6D,SCN3A,SCP2,SOX6,SFPQ,KIF21A,PPM1E,FERMT1,ASAP3,SHC4,FBXO11,CNKSR2,ABLIM3,SLC1A2,ZNF365,PPP4R3A,SLC6A1,LRRC55,SHANK2,SMARCC2,IGSF9B,RIMS1,FAM219A,DOP1A,SON,MYT1L,SP4,ZC3H13,RBM26,TROVE2,ITPRID2,SAMSN1,NKAIN2,ELOVL4,ARHGEF9,VPS13A,C3orf70,PLCB1,SLC37A2,ATP11A,KAZN,ROBO3,MCF2L,CAMSAP2,FAM208A,KLHL4,ANO4,VWA3A,TCF4,DMXL2,ZEB1,WDR7,FAM189A1,PCDHB9,SLC19A3,PSD3,ARHGEF12,USP32P1,RNF216P1,PMS2CL,CRB1,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,R3HDM1,RBFOX2,DOK6,RGMB,TRIO,TRPS1,LRTM2,HIRA,SLAIN1,USP1,ZNF709,BEST1,TBC1D15,VSNL1,XRCC4,ZNF32,ELFN1,PLPP4,ZBTB16,TMEM237,SLC30A3,CADM2,PRDM2,STOX2,ADAMTS9,SCG2,CIAPIN1,FIP1L1,TRIM16L,WIPF2,EPM2A,FZD3,RTN4,SMIM8,HNRNPA3,TTC7A,SSPN,PIANP,FRMD6,SLC4A10" MicroRNA hsa-miR-2113:mirSVR_lowEffct hsa-miR-2113:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.70E-169 1.52E-165 1.83E-167 1.68E-166 441 1881 "KCNH8,ACLY,ABHD6,EMILIN3,ARID1A,CSMD3,DSCAML1,CCDC85A,TMCC3,ADD3,ERMN,DPY19L2P4,SLC24A4,ZNF608,MTUS1,GPR158,OSBPL1A,KIAA1324,OSBPL6,LRRC7,USP35,ALCAM,MRTFA,CDC42BPA,ANK2,ANK3,FGD2,SMIM29,PPFIA1,SUGT1P4-STRA6LP-CCDC180,MAGEE2,DGKZ,PHYHD1,LRRC4C,TNRC6C,PPFIA3,CDK10,PPP4R4,PDXK,TMEFF1,SPTBN4,CDK13,MTMR9,N4BP2L1,DOCK11,ADAM15,BACH1,BCHE,BMPR1B,ST3GAL5,FUBP1,LINC00906,BTK,LDLRAD4,CA8,KALRN,PTBP2,PRC1,KRIT1,CERS5,DGKI,REPS2,CDC42,ZMYM4,L3MBTL4,LOC730101,ZNF445,CLGN,RCBTB2,CASC2,TAOK2,NDST3,KMT2C,RAB28,KIAA1549L,CLCN4,ABCG2,NIPBL,BTF3L4,TOGARAM2,CHD1L,CREM,SH2B1,NCOR1,CSF1R,RGS6,LRIG1,MICAL2,SIPA1L1,PDE4DIP,KIAA0040,CX3CR1,ARHGAP32,ARHGAP24,FRMPD4,EARS2,RASSF2,LONRF1,MATR3,RIMS3,KCTD8,DGKG,DAPK1,ZEB2,TIAM2,KIAA0319,BLOC1S6,ZC3H11A,POM121,RHOBTB1,SACS,SPOCK3,SV2A,RABGAP1L,WDR20,ARNT2,GRIN3A,RAB39B,USP3,DOCK2,DMTF1,ARRDC4,DTNA,ABCC9,E2F5,E2F6,EDNRA,EDNRB,HIPK3,FCF1,KLHL5,FRY,PHF20L1,ABI2,TMEM132E,RASA4,GOLGA7,SORBS3,ELAVL3,ELAVL4,ELN,C8orf37,EPHB1,ANKRD13B,SRRM1,ERBB4,SPEG,TMEM74,TLR7,RRAGB,EZH1,CLVS1,CACNG2,ACSL4,CORO2B,SEC24B,MED12L,KIAA1109,FGFR1,PRKAG2,FHL1,FLT1,PSD2,SPECC1,FAM49B,CAMKK2,ATP2C1,ERGIC3,NSG2,DACH2,ST6GALNAC3,DOT1L,ABLIM2,PHYHIPL,STAG2,GABRA5,CHL1,ILDR2,B4GALNT1,C15orf41,SRRM4,MYOZ2,TUBGCP4,CYP46A1,KIRREL3,ZNF276,STARD3,CBX1,KDM2B,GNAO1,GNAS,ADGRA3,FUT10,STON1,LPAR4,NUDT21,GPR37,GRIA2,DIDO1,GRID1,RFFL,ADAMTS8,GRM5,GRM7,GRM8,TMEM25,AP4S1,SOX21,GUCY1A1,FAM222A,ATG4C,UBE2QL1,TOX2,PADI2,MIER3,AGBL5,TLX1,ZDHHC15,SHISA6,CELF5,ICA1,MSL1,IDH3B,C5orf24,PLD5,IL6ST,BRINP3,SLC6A17,NME9,KCNA1,KCNK2,KCNQ2,STMN1,LIG4,FGFBP3,MAP6,MARK1,MAT2A,MBD1,MBNL1,SRSF12,SCAMP5,AFDN,MMP16,ADAM22,MSR1,NRBP2,CTNNA3,RSPO2,MYO5A,NEXMIF,MYT1,NAP1L1,NCAM1,NELL1,NELL2,NEUROD1,NF1,NOVA1,NPR2,SLC11A2,NTRK2,LOC100128398,GPR137C,SNTG1,CNTN3,PCDH9,CDK18,PDCD2,PDE1C,PDE3A,PDE4B,PDYN,GPR85,OLA1,FAM218A,FAM216A,ST8SIA5,ANKRD16,LRP12,SCHIP1,SEPT4,MBOAT7,MINDY2,PPP2R2C,PPP2R5C,RANBP3L,MASP1,SLC22A23,APTX,SNRK,PLPPR1,UHRF1BP1,ELOVL2,PTN,PTPRB,PTPRE,ZNF793,SH3TC2,REV3L,FIGN,TTLL7,SEC61A2,PBRM1,RNASEL,KLHDC8A,CYB561D1,ROBO1,CCDC102B,SNX22,NEK11,RPL15,UEVLD,SPIN3,ZC3H14,RPS6KA2,LGR4,ABCA11P,KCNIP3,CLIP1,RTN1,ZNF331,MAPK12,ATXN2,LRFN5,ASIC4,SUPT20H,SCAF8,ITSN1,FAM102A,SH3GL3,FUZ,FHOD3,ST6GAL1,SLITRK3,ZNF365,FAM81A,SLC6A1,KANSL3,LRRC55,SLC8A3,KBTBD4,BTBD7,SLC20A2,SPHKAP,SLIT1,NAXD,GKAP1,RCOR3,ANKRD36,MBD5,PDZRN3,SOX5,KIF21B,SOX11,ZSWIM8,TEX2,UNC5B,PEG10,PBLD,CLASP2,ELOVL4,NEK4,SEPT8,KANK1,GSE1,FGD4,VPS13A,ADAMTS17,C3orf70,MTCL1,WWC1,TBX15,VWC2,SATB2,TCF7,PCDHGA11,SYNE1,FAM189A1,OBSL1,PUM2,TEX15,ZFPM2,AP4E1,TIAM1,MTMR14,ASXL3,ERCC6L2,TMOD1,PIK3R5,RBFOX2,TPM1,ZNF346,PDSS1,PPIL6,DCBLD1,TSC1,ANO5,SSBP2,TUB,CLHC1,FAM155A,UBE2H,UBE3A,SLAIN1,PITPNB,PLEKHH2,USP1,VLDLR,SLC47A2,ZIC2,MICU3,GPR158-AS1,NDRG4,MKRN3,CELF4,ZBTB16,TMEM237,EML6,PLPPR5,WNK1,CADM2,LRP8,SLC38A1,PRDM8,XKR7,TMEM178A,CIAPIN1,MDH1B,FIP1L1,WNK2,FAM13C,AMN1,FZD3,SMIM8,PHTF2,NHSL1,SNX14,SSPN,FRMD6,SPATA13" MicroRNA hsa-miR-802:mirSVR_lowEffct hsa-miR-802:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.67E-169 3.18E-165 3.79E-167 3.49E-166 432 1809 "CPNE2,ACADM,ARID1A,CSMD3,ADD1,BRAP,PLEKHH1,SNX30,ADORA3,NLGN4X,AP1B1,ZNF608,GPR158,HECW2,RTL9,OSBPL1A,WDR35,AK2,SEMA6A,PITPNM2,OGT,CDC42BPA,FGD2,LCORL,MAP4K3,APBB2,USP37,SHTN1,AQP4,PPP4R4,ASCL1,MARK4,ASPH,ALDH4A1,ATM,SLC4A4,STX16,MTMR9,NOL4,ADAM23,BCL2L2,ZNF599,SYNJ1,ARHGEF7,IL33,BTRC,CFAP410,CACNB4,CALB1,CALM1,CAMK2G,TRIM41,CAST,SPAG9,CLDN10,REPS2,CDC42,CDH2,LRRFIP1,DLGAP1,CCPG1,CIART,ADGRG1,CASC2,PLAA,NRXN1,TJP2,FADS2,ABCG2,QKI,COL4A5,COL9A1,LETMD1,AKAP5,SLC4A7,ABI3BP,TBPL1,TOGARAM2,CHD1L,SLC35F1,PREPL,RBM39,CRHBP,HAPLN1,TRIM69,MROH8,SNCAIP,MICAL2,OSBPL3,NCAN,SOCS5,CNTNAP2,CST3,DZIP3,GREB1,ECE2,ARHGAP32,ARHGAP24,DCAF8,TOX,TBC1D5,KIAA0586,IST1,TOMM20,PITPNC1,ARMCX2,DNAJC6,C8orf34,MYEF2,CEP170,KLHL3,ZC3H11A,GSDME,SPOCK3,SRGAP3,FAM107B,KIF19,DLG2,DLG3,DLX1,GRIN3A,USP3,NR1D2,DOCK2,SLC12A6,DTNA,DUSP9,MAMLD1,EDNRB,TMTC1,FAM13A,SUGP2,EGFR,MRO,EIF4G2,ELAVL3,C8orf37,VPS13B,LRRC17,GPHN,STX2,DENND4A,NCALD,ZNF549,TMEM74,ETV1,RTN3,ANKMY1,NRN1,EFEMP1,ATP8A1,FCGR1A,FKTN,FECH,SEC24B,SLC9B2,FER,FGF12,FGFR1,FGFR3,CAMSAP1,POLK,FOXG1,SYNCRIP,RGPD5,FOXO3,FLT1,SLC37A3,ARFGAP2,ATP2C1,KHDRBS3,NSG1,STAG2,GAB1,GABRA1,GABRA3,GABRA5,GABRB3,GABRG1,HBS1L,ZMYND11,SALL3,IP6K3,ATP8A2,CPLX2,DNER,GATM,IGSF5,CYP46A1,COPS8,SPIN1,MSL3,GLUL,PCDH11X,KDM2B,HTATSF1,KCNMB4,FERMT2,GOLGB1,GPD1,GPM6B,GPR12,STON1,NUDT21,EML4,GPR37,PCLO,RAPGEF4,RAPGEF1,GRM1,MFSD2A,RABL2A,WIF1,ZHX1,FRMD5,AGBL5,HNF4G,NEGR1,DHX35,HSF2,IL6R,INSM1,ITGAV,ITPKB,KCNA1,KCND2,KLRC3,LAMP2,LIFR,PIK3AP1,ZNF667-AS1,MAT2A,MBNL1,MBP,MDM4,MEIS2,MIA2,KITLG,MID1,MITF,AFF1,MMP16,SAMD5,SESN3,MSI1,ADAM22,HS6ST3,MYO5A,NEXMIF,MYT1,NCAM2,ZC3H12B,CCDC13,NELL2,NF1,OTOGL,NOVA1,HCN1,NTRK2,IGSF11,OPCML,DPY19L2P2,PCDH8,PCMT1,PCSK5,PDGFRA,PFKFB2,OLA1,SERPINI1,CCSER2,XRN1,SMIM7,PNMA3,PDZRN4,LRP12,RETREG2,EPB41L4B,TNPO2,PPP2R5C,MAPK7,BCAS3,SLC22A23,UHRF1BP1,TMEM260,PTPRB,PTPRD,FAM120C,C1orf109,TTC13,QDPR,USP47,PLEKHB2,SH3TC2,VEPH1,ZDHHC14,GTDC1,ZNF532,ROBO1,RORB,EPHA10,UEVLD,FBXW7,ZC3H14,ATP8B4,RXRA,STX1B,DGLUCY,ATXN2,LRRTM4,FAM19A1,SCP2,FNIP1,TNFRSF19,SLC30A10,PEAR1,SOX6,SUPT20H,SH3GL3,PPM1E,ARX,FERMT1,KIF16B,NTNG1,CHD9,CNKSR2,DZIP1,SLC1A3,PPP4R3A,BTBD3,SEPHS1,RAB3GAP1,ARHGEF40,SHANK2,SLC15A2,SLCO1A2,SLIT1,NAXD,LIMCH1,MYO16,DOP1A,SON,KIF21B,ZHX3,ZSWIM8,NMNAT2,UHRF1BP1L,SPP1,KDM4C,ARHGAP26,CDK19,MCF2L2,PBLD,ITPRID2,SSTR1,LARP4,STAU1,CEP68,KANK1,SULF2,GSE1,NECAB1,SYN2,COBL,ANKRD28,TAC1,TACC1,KAZN,CAMSAP2,KLHL4,ATMIN,VWC2,TCF12,PHF24,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,C18orf54,TGFBR3,ZNF106,TIMP4,TLR4,HEY2,TMPO,RIMBP2,RBFOX2,TPD52L2,RGMB,SYNPO2,RUNDC3B,TRPC1,TTTY15,CLHC1,TMEFF2,CADM1,UBE2H,LINC00689,PITPNB,FLRT2,PLEKHH2,WIPF1,GUSBP1,ZIC1,TRIM9,ZNF45,FMN2,MKRN3,ZNF195,PLPPR5,ZFAND5,DHX33,PRDM2,PRTFDC1,SLC38A1,CSDE1,EVI5,GAL3ST3,NAV3,FIP1L1,SLC17A6,KAT6A,ADAMTSL3,MSRB3,NHSL1,FXR1,FRMD6,ST8SIA2" MicroRNA hsa-miR-4262:mirSVR_highEffct hsa-miR-4262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.10E-169 3.99E-165 4.69E-167 4.32E-166 432 1810 "CPNE2,KCNH8,C3orf14,NCKAP5,ACTN2,FMNL2,SLITRK1,CCDC85A,BRAP,SLC12A5,ERMN,UNC5A,MTUS1,HECW2,AGT,OSBPL1A,OSBPL8,ADGRF5,C1QTNF3,FAM135A,CDC42BPA,DPP10,PPFIA1,DDO,API5,CDC14B,SEMA4G,MADD,CAPRIN2,ASPH,NUMB,DDX3Y,ATM,SLC4A4,ATP2B1,ATP2B3,RNF182,ADGRB3,BCHE,NAE1,SCAPER,JAZF1,WASF1,CA8,CACNB2,CALB1,KALRN,PTBP2,CAMK2D,CAMK2G,CAST,C1orf52,LRBA,CDH8,LRRFIP1,DIS3L,CFL2,RCBTB2,CHN2,CASC2,SYNPR,KMT2C,NRXN3,NRXN1,NMT2,NIPBL,CNTN1,AKAP7,ARMC8,FAM149A,AKAP6,SLC25A27,AKAP5,SLC4A8,ABI3BP,TBPL1,AHCTF1,BAG4,SLC35F1,SEC31B,C2CD2,HAPLN1,SEC24C,FEZ1,OSBPL3,ATRNL1,VCAN,PUM1,ZSCAN23,USP6NL,CCDC144A,CYBB,DOCK4,GAPVD1,TOX,ZFYVE16,LONRF1,DGKB,PABPC5,ELMSAN1,ZEB2,BLOC1S6,POM121,SPOCK3,G3BP2,WDR20,ARNT2,DLG2,DYNC1I1,NR1D2,CDON,CPEB2,DPYSL2,ABI1,PDCD6IP,ARRDC4,DTNB,DNAJB6,ABCC5,E2F5,EDNRB,CNNM1,KLHL5,PHF20L1,SUGP2,MBNL2,AASS,GOLGA7,KCTD3,ELAVL2,PLEKHA1,ELAVL4,CALCRL,USPL1,EMX2,EN2,EPHA5,KCNMB2,NCALD,EFS,CDKL3,RRAGB,F5,CLVS1,RPS6KC1,TMEM132C,ZIC4,FDFT1,FER,KIAA1109,BAIAP2,PRKAG2,SUCO,FLT1,SMC2,UFM1,NPTN,ST6GALNAC3,NSG1,STAU2,PNMA2,GABRA1,GABRA2,ZNF44,CHL1,GABRG2,CAB39,GAD2,ZMYND11,ZNF559,DNER,GATM,ARFIP1,GPR162,ADAM28,TCERG1,GLS,PCDH11X,RAB40B,GNAS,PSRC1,GPD2,CCDC184,GPR22,NUDT21,CECR2,RAPGEF4,GRB10,GRIA2,DIDO1,GRIA4,GRIK2,GRIK3,NR3C1,GRM1,GRM5,GRM8,CIT,KIF3A,WIF1,UBE2QL1,ZHX1,MIER3,HLF,HMGCL,NEGR1,HSF2,HSPA1L,IRF8,ZNF181,SOWAHA,DOCK7,JAK2,KCNJ10,KCNMA1,IPO5,LIG4,PAXBP1,LMO1,ARHGAP12,NCOA7,MARK1,MAT2A,MATN3,ADAM11,ZNF680,SESN3,MSR1,RSPO2,MYBPC1,NAP1L1,SFR1,NF1,CNOT4,NOVA1,HCN1,IGSF11,GPR88,OPHN1,GPR137C,PBX1,PCSK1,PRTG,PDE3B,PDGFRA,PFKFB2,PIK3C2A,XRN1,PLP1,PURG,LRP12,SCHIP1,EPB41L4B,FAT3,PPARA,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,CEP41,MAPK4,EPDR1,PROX1,CNNM2,BDNF-AS,MTMR10,PTHLH,SPDL1,OCIAD1,C1orf109,ZNF844,PPP2R3C,QDPR,ACSS3,RASGRF2,FIGN,RFX2,TTLL7,SLC25A36,PBRM1,ZFHX4,TMLHE,GSTCD,ROBO2,CCDC25,PCMTD2,RPE65,ARMH4,ATP8B4,ACER3,LRRK2,CNTNAP3,PTGR2,CLIP1,ZNF568,RYR3,FAM192A,SEMA6D,SCN8A,FNIP1,SUPT20H,SCG5,ITSN1,DOCK10,MAGI3,CHD9,FBXO11,FNDC3A,CNKSR2,CTXN2,SLA,BTBD3,EPN2,PKNOX2,CCDC88A,SLC11A1,NAPB,SLCO1A2,CPEB4,ZKSCAN3,DMRTC1,MYH15,SMARCE1,ANKRD36,RIMS1,SNAP25,MBD5,CMTR2,SNRPN,PALLD,PDZRN3,UNC80,USP33,DOP1A,TRERF1,MYCBP2,SPP1,TEX2,KIF1B,ZBTB43,RBM26,NPAS3,LMO3,C11orf87,SRPK2,EPB41L3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,GSE1,KLHL7,PRRC2C,SYNE2,VPS13A,MTCL1,CAMTA1,TAF9,CAMSAP2,ADGRL3,TBCEL,ANO4,ATMIN,SIN3B,DMXL2,ZFP90,TCF7L2,CLASP1,SZT2,SYNE1,TMEM151B,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIK3,SIRT1,KHDC1,C18orf54,LEFTY2,AP4E1,THBS4,MTMR14,DDHD1,HEY2,SYNPO2,TRPC1,RUSC1,ANKRD20A2,TTTY15,RFTN2,SGK3,PITPNB,USP1,MEAF6,CCDC14,ZNF781,XRCC4,SF1,ZBTB14,ZIC2,ZIC3,MICU3,ZNF74,NDRG4,SPIRE1,PLPPR5,SYNC,WNK1,EMSY,LINC02210,PRDM8,HPS4,SEMA3B,MDH1B,PCDH15,MVB12B,PARP11,GOPC,PAK5,PHTF2,ZNF248,IFT88,SLC4A10,CPNE4,LAS1L" MicroRNA hsa-miR-543:mirSVR_highEffct hsa-miR-543:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.08E-168 1.73E-164 2.01E-166 1.85E-165 417 1693 "KCNH8,ACADM,CLK4,C3orf14,ACTN2,FMNL2,GALNT13,BRAP,SLC12A5,ADORA2A,PWWP2A,SLC44A5,ZNF608,KLHL13,OSBPL1A,OSBPL8,C1QTNF3,SRPX,ABCD2,FAM135A,PARG,ALS2,DDO,API5,CDC14B,TMEM263,CASK,ZFYVE28,LINC00173,MARCH3,ASPH,DDX3Y,ATM,STX16,ATP2B1,B3GALT2,NOL4,ADGRB3,SEC11C,DST,SYNJ1,SCAPER,CASTOR3,JAZF1,WASF1,CACNB2,CALB1,CAMK2G,SPAG9,MAP7,C1orf52,ARHGEF2,CDH2,CDH10,ZMYM4,LRRFIP1,L3MBTL4,DIS3L,RCBTB2,CHN1,CHN2,NRXN3,NMT2,NGEF,TJP2,DNAJB5,QKI,NIPBL,TMEM155,AKAP7,ARMC8,AKAP6,AKAP5,SLC4A8,GAL3ST1,AHCTF1,MYRIP,ZNF521,CP,SLC35F1,CLOCK,C2CD2,ENTPD4,HAPLN1,RNF14,GDA,MROH8,OSBPL3,SUSD5,ATRNL1,VCAN,SOCS5,PHF14,CTH,CCDC144A,GAPVD1,FRMPD4,TOX,ZFYVE16,MATR3,DGKB,PABPC5,GIT2,SIRPA,ELMSAN1,C8orf34,ZEB2,HEPH,FBXL5,MAGI2,ZC3H11A,DDX46,RHOBTB1,SMG7,SACS,SPOCK3,SRGAP3,NTM,ARNT2,SEC16A,DLX1,GRIN3A,HS3ST2,NR1D2,CPEB2,DTNA,GOLT1B,EDNRB,KLHL5,SUGP2,GOLGA7,ASB3,ELAVL2,PLEKHA1,ELAVL4,PAN3,EIF1,EMX2,EN2,VPS13B,EPHB1,KCNMB2,GPHN,STX2,EPS8,DENND4A,CDKL3,ADGRV1,EYA1,F3,CLVS1,FAM198B,TMEM132C,FDFT1,GORAB,SEC24B,KIAA1109,FGF12,FGF13,PCYOX1,RGPD5,NELFCD,TACC2,NPTN,ST6GALNAC3,ZNF512,FYB1,DKK3,GABRA1,CAB39,GAP43,GATM,ARFIP1,GGT7,PPARGC1A,GK,TCERG1,SPIN1,GLS,TOX3,PCDH11X,ZNF638,RAB40B,GNAO1,GNAS,ADGRA3,GPM6A,DIDO1,GRIK2,NR3C1,GRM1,GRM5,GRM8,CIT,BTN2A1,PTPN5,MFSD2A,PSIP1,FAM222A,WIF1,MAEL,HPS5,HMGCR,HNF4G,NEGR1,HSF2,MSL1,SOWAHA,IGFBP1,DOCK7,INPP1,SLC35G1,METTL21A,KCNA1,KCNA6,KCNK2,KCNMA1,CREG2,IPO5,LAMP2,PAXBP1,LMO1,HECTD2,ARHGAP12,NCOA7,C2orf80,MARK1,LYPLAL1,MATN2,MDM4,MEIS2,KITLG,MOBP,MOG,MRPL42,MSR1,RSPO2,MYCN,NAP1L2,NELL2,OTOGL,CNOT4,NRCAM,GPR137C,GLIPR1L2,SNTG1,PCDH8,PCSK1,PRTG,PDE3B,SERPINI1,PLP1,SMIM7,SCHIP1,SPATA6,NXPH1,SH3KBP1,PPARA,PPP2R2C,PPP2R5C,PPP3CB,CEP41,GRAMD1C,PROX1,CNNM2,GON4L,PTCH1,PLPPR1,PTHLH,ELOVL2,SPDL1,TMEM260,PTPRB,PTPRD,PEX2,QDPR,PID1,TMEM255A,RAD17,ZNF793,DBX2,PBRM1,ZFHX4,GSTCD,CYB561D1,ROBO2,TMEM206,RPE65,FBXW7,ATP8B4,ACER3,LRRK2,CNTNAP3,PTGR2,ABCA11P,CLIP1,RTN1,CCDC112,LRFN5,SCN8A,SCP2,SLC30A10,IL17RB,SEC14L1,ASRGL1,SGK1,DOCK10,MAGI3,FHOD3,CNKSR2,BTBD3,RUFY2,SLC11A1,NAPB,CPEB4,SLN,ZNF667,SMARCE1,ANKRD36,RIMS1,SNAP25,MBD5,LMBRD1,SNRPN,UNC80,SON,MYT1L,FNBP1,EMC1,UHRF1BP1L,KDM4C,TEX2,PEG10,ZBTB43,RBM26,NPAS3,LMO3,SRPK2,TROVE2,RGL1,KANK1,PRRC2C,VPS13A,MTCL1,UNC5D,EHBP1,DMXL2,TCF7L2,TRIM2,SYNE1,TMEM151B,PCDHB6,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIRT1,ZFPM2,CRB1,AP4E1,HHIP,ZFP91,HEY2,SYNPO2,PDSS1,RUNDC3B,TRPC1,ZMYND8,ANKRD20A2,ANO5,TTTY15,RFTN2,SGK3,UBE3A,SLAIN1,OSBP2,PLEKHH2,CCDC14,WIPF1,SLC13A3,XRCC4,SF1,PCDH20,ZIC1,ZIC2,ZNF74,LYPD6,REEP1,EML6,ANKS1B,LAMP5,ZFAND5,WNK1,EMSY,CADM2,CSDE1,EVI5,LINC02210,PRDM8,HPS4,PCDH15,MVB12B,EPM2A,GOPC,PAK5,SMIM8,SLC39A12,SSPN,NETO1,RNF146,CPNE4,SENP7" MicroRNA hsa-miR-1259:mirSVR_lowEffct hsa-miR-1259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.71E-168 2.65E-164 3.04E-166 2.80E-165 445 1928 "ACADM,ASIC2,NBAT1,CSMD3,ADCY8,ADD1,ADD3,BRAP,SORCS1,GRAMD1B,UNC5A,PWWP2A,SNX30,SLC24A4,ZNF608,INTS2,PCDH19,HACE1,KIAA1324,ADGRF5,SMIM17,CEP126,PCDH10,SYT13,DPP10,LCORL,MAP4K3,ANXA7,USP37,PPP4R4,LINC00173,ASPA,TMEM108,ATM,ATP2B1,ZNF582,ALDH7A1,MTMR9,NOL4,ADGRB2,ADGRB3,MPDZ,BMPR1B,FUBP1,MTMR2,JAZF1,C5,NIPA1,BSN,RAB29,BTRC,CACNA1B,CALB1,VXN,ISPD,MAP7,RUNX1T1,SCARB1,C1orf52,LRRFIP1,MAGI1,DLGAP1,CCPG1,NUMBL,CACNA2D2,SRSF11,SYNPR,B4GALT6,NDST3,KMT2C,EPS15L1,HECTD1,MAP4K4,NIPBL,ARHGEF6,PCYT1B,ARMC8,AHCTF1,BAG4,CNRIP1,SLC35F1,RBM39,CRHBP,AKAP12,RNF14,ANKRD44,PHACTR3,FAM169A,DZIP3,PLCXD3,PNPLA8,NRSN1,PUM1,RIMS2,ST18,USP6NL,EDRF1,NOS1AP,BOC,MYADM,TOX,ZFYVE16,LONRF1,KIAA0586,KCTD8,IP6K1,DBT,ELMSAN1,JAKMIP2,ZBTB24,HEPH,MFAP3L,HP1BP3,COPS7A,DDX46,ALKBH8,PLPPR4,SNAP91,SRGAP3,NTM,NR1D2,CDON,CPEB2,DRD1,GNE,DTNA,DYRK1A,ABCC5,E2F6,EBF1,EDIL3,EDNRA,MBNL2,ABI2,COPS4,PLEKHA1,EML1,PAN3,EPB41L1,EPHA5,EPHB1,EPS8,ETV1,DNAJC27,ADGRV1,NRN1,FAM198B,SCML2,EFEMP1,CEP78,TESK2,SLC9B2,MED12L,FGF1,POLR1B,FGF13,MEX3B,CAP2,RGPD5,ATP13A4,ANKFY1,EFCAB2,PDLIM5,TPK1,NRG3,MPP6,TVP23A,ZMAT1,MEGF10,GAB1,HRASLS5,GABRA5,GABRG1,B4GALNT1,ARPP21,ERAP1,WASF3,KIAA1841,GCNT2,MMADHC,PCDH17,TCERG1,COPS8,RAB30,TOX3,PCDH11X,ZNF638,POLL,LUZP2,GPM6A,ATF7,GPR37,CNTRL,RAPGEF4,GRB10,GRIA2,DIDO1,GRIA4,RFFL,GRIK2,GRIK3,NR3C1,GRM8,GUCY1B1,MAEL,RASSF8,FRMD5,NCKAP1L,GABARAPL2,ZDHHC15,LINC00667,IGF1,ZIC5,DOCK7,PLD5,IL12A,ZNF385B,LRRTM1,SLC35G1,KCNC2,KCNK1,KCNK2,KCNN2,KIF2A,KIF5A,KIT,CYP27C1,LIG4,VWA5A,NCOA7,C2orf80,PACRG,MAP2,MARK1,IL17D,CHIC1,TM6SF1,LRP1B,SHC3,KITLG,SAMD5,CCDC80,MSR1,CTNNA3,LAYN,MYO9A,NAP1L2,NCAM2,NEFM,NF1,SLCO1C1,NFIA,CNOT4,NOVA1,DNHD1,NPR2,NPTX2,OXTR,KCNK10,GLIPR1L2,CNTN3,PBX1,PCDH8,PDE1C,PDE4D,PDGFRA,BEST3,PFKFB2,NLGN3,SSH1,PIK3R1,XRN1,FAM216A,PLCB2,FTO,MTRF1L,PURG,PMP2,PMP22,RC3H2,LRP12,PSAT1,SDK2,FAT3,DRAM2,PPP2R5E,PPP3CA,PRKAB2,RASGEF1B,MAPK9,FITM2,GRAMD1C,SYTL2,GON4L,MDGA2,PTCH1,PLPPR1,MTMR10,PTPRB,OCIAD1,PTPRN2,FAT4,RAP1GDS1,ARID4A,FEZF2,ZDHHC14,ERI2,RFX3,PRIMA1,KLHL11,PBRM1,CCDC82,ROBO1,ROBO2,RPE,TMEM100,FBXW7,SPIN3,ZC3H14,ACER3,LGR4,PTGR2,HUNK,RMI1,SALL1,ATXN1,ATXN7,SLC30A10,FERMT1,NTNG1,ST8SIA1,DZIP1,PAAF1,SLC1A3,FAM81A,SLC8A1,SLC8A3,CCDC88A,NAPB,SLC15A2,SLC22A4,SLIT1,EPC1,MAST1,SORCS3,CABCOCO1,LMBRD1,FAM126B,UNC80,DOP1A,SON,MYT1L,SP4,MYCBP2,KDM4C,KIF1B,MCF2L2,SRPK2,TROVE2,ITPRID2,ZNF302,SSTR1,SEPT8,STXBP1,AJAP1,FGD4,PRRC2C,NUDT10,SYT1,ANKRD28,TAC1,ANKRD12,PJA1,CAMTA1,UNC5D,KLHL4,DMXL2,RPGRIP1L,CLASP1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,TEK,DICER1,DICER1-AS1,CRB1,AP4E1,HHIP,THBS4,TLR4,HEY2,DAAM2,NPL,ZNF384,TRPC3,PPIL6,ANKRD20A2,SSBP2,TMEFF2,HEPACAM,ZNF610,EIF4ENIF1,UBE2H,SLAIN1,FLRT2,MEAF6,CCDC14,WIPF1,RICTOR,XPO1,XRCC4,PCDH20,MICU3,ZNF28,GPR158-AS1,MKRN3,LYPD6,CELF4,ZNF142,TMEM237,ZNF184,SPIRE1,WNK1,MAP3K12,EMSY,PRDM2,STOX2,SCG2,HPS4,RTN4,PHTF2,CASC15,CERS6,ADAMTSL3,MSRB3,SLC39A12,FXR1,FRMD6,CPNE4" MicroRNA hsa-miR-526b*:mirSVR_highEffct hsa-miR-526b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.26E-168 4.08E-164 4.63E-166 4.27E-165 404 1592 "KCNH8,NCKAP5,SORCS1,KIDINS220,SLC24A4,ZNF608,ABCD2,MRTFA,SEMA7A,USP28,SUGT1P4-STRA6LP-CCDC180,APP,SHTN1,AQP4,LINC00173,STK33,CAPRIN2,RASL11B,ASTN1,ATP1A2,SLC4A4,ATP1B3,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,NRP2,SCAPER,MTMR3,JAZF1,CALB2,MAP7,PRC1,USP6,C1orf52,SEPT7,TIGD7,CLGN,CFL2,CHGA,JAM2,TAOK2,EPS15L1,ZFYVE9,ABCG2,IGLON5,SLC25A27,BTF3L4,AKAP5,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,PLPPR4,SACS,G3BP2,DMD,OLIG1,USP3,DMTF1,DPYSL2,DRD1,DTNA,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,SNX29,EDN3,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,GMPR2,EZH1,F3,F8,WAC,ACSL4,TAOK3,CORO2B,CEP78,SLC9B2,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ATP2C1,ST6GALNAC3,FYB1,ZMAT1,GABBR1,GABRA1,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,ADAM28,RAB30,GLS,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,NR3C1,GRM7,CIT,LINC00839,TMEM25,AP4S1,IRAK3,HAS2,HPS5,SMAP1,HTR5A,MSL1,DOCK7,ITGAV,JAK1,METTL21A,OLFM3,KCNJ10,KCNK1,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,LAMP2,SFXN5,SYTL4,HECTD2,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MOG,MSR1,RSPO2,MXI1,MYCN,MYH6,NACA,NCF2,NDP,SFR1,NELL1,NELL2,CNOT4,OCRL,OGG1,OPA1,GPR137C,CNTN3,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,HMGCLL1,PRRX1,RETREG2,EPB41L4B,DRAM2,CRLS1,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,APTX,PIGG,PTHLH,PXK,PTPRD,PTPRO,FAM120C,RAB5B,CEP97,TMEM255A,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,GTDC1,SLC25A36,RNASEL,ZFHX4,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,SHC4,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,PPP4R3A,BTBD3,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,SOX2,IQSEC2,ZBTB43,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FGD4,PLCB1,ANKRD12,CAMTA1,MCF2L,CAMSAP2,ADGRL3,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,RALYL,PCDHB10,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,KAT6B,TNS1,TPD52L2,NPL,RGMB,UBC,UBE3A,UBTF,UCHL1,CCDC14,VLDLR,TBC1D15,VSNL1,XPO1,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,CA10,MAP3K12,EMSY,CADM2,PRTFDC1,SLC38A1,RGMA,CSDE1,PRDM10,RNF103,PCDH15,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,SLC39A12,FXR1,FRMD6,IFT88,NETO2,DPF3" MicroRNA hsa-miR-200a:mirSVR_highEffct hsa-miR-200a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.43E-168 4.73E-164 5.32E-166 4.90E-165 399 1553 "ABCF1,SYN3,NCKAP5,CSMD3,ADD1,ADD2,ADD3,PLEKHH1,ADORA3,KIDINS220,BEND6,SLC44A5,RTL9,KIAA1324,SMIM17,PCDH10,AMPD2,UPRT,ALS2,SHTN1,MIER1,TMEFF1,ARNTL,CDK13,STK33,ASPH,ASTN1,ATM,STX16,ATP2A2,ADAM23,BACH1,NRP2,ZNF599,ST3GAL5,MTMR2,JAZF1,GPC2,OSGIN2,THSD7A,KALRN,PTBP2,CANX,SYT6,CAST,BRSK2,CCNH,USP6,SEPT7,CDC25B,CDC27,CDH10,L3MBTL4,TIGD7,DIS3L,CFL2,CHM,CHN2,PPT2,QKI,HECTD1,NIPBL,CNR1,COX4I1,AHCTF1,ACBD5,MYRIP,CPS1,SEC31B,PREPL,CRMP1,TRIM69,MROH8,ARHGEF10,CSNK1E,CSNK1G3,ATRNL1,VCAN,NCAN,PDE4DIP,PLXNA4,ERC2,APPL1,PHF14,CTNND2,NRSN1,ZSCAN23,DCAF4,EDRF1,KIAA0408,DOCK4,HDAC9,DAPK1,DBI,ARMCX2,ZEB2,CEP170,TMEM130,LYPD1,RHOBTB1,SNAP91,SV2B,GRIN3A,DYNC1I1,CPEB2,GNE,DYRK1A,ABCC5,ATL1,RBM12,YAF2,EGFR,KMT5B,GOLGA7,KCTD3,ELAVL2,ELAVL4,TMEM35A,PAN3,EPHB1,STX2,IGSF6,ANKMY1,EYA1,DLC1,ST3GAL6,TESK2,FER,OLFM1,POLR1B,FGF13,SUCO,RGPD5,FLT1,NELFCD,SMC2,UFM1,TPK1,KHDRBS3,CELF1,STAU2,MSANTD4,PHYHIPL,MEGF11,MEGF10,GABRA1,GABRA2,FAM120B,ZNF234,NEK6,C15orf41,GCNT2,PPARGC1A,TCERG1,GLS,PCDH11X,ZNF638,CBX1,KDM2B,LOXL3,GPD1,GPD2,LILRA1,GPR12,PCLO,RAPGEF4,GRB10,GRIA2,GRIA4,ADAMTS13,ADAMTS8,GRIN2D,NR3C1,ATE1,GSN,KIF3A,GSTT2,LINC01551,GUCY1B1,GYG1,WIF1,HPS5,NXPH2,MIER3,HLF,ACOT7,HMGB1,HNMT,HTR2A,HTR5A,EID2B,IRF8,RBPJ,DIPK1A,INSM1,KCNJ11,IPO5,STXBP5,LAMP2,MARK1,AQP11,MBNL1,MDM4,MEIS2,PPM1L,AFDN,CD200,COL28A1,SESN3,CCDC80,RSPO2,NAP1L2,NAP1L3,NFE2L2,DNHD1,SLC11A2,NRCAM,HCN1,OGG1,P2RY1,GPR137C,PCDH8,PCDH9,PCSK5,PDCD2,BEST3,ZNF655,PLCL1,EPN1,SMIM7,PNMA3,PMP2,TRHDE,STRN3,SCHIP1,ING3,SPATA6,MED1,PPP2R5E,PRKACB,MAPK9,GDPD1,SYTL2,GON4L,CNTLN,PTCH1,MTMR10,PTHLH,SPDL1,TMEM260,PTPRD,PTPRE,PTPRG,PEX5,SH3TC2,FAT4,DBX2,KHDRBS2,MSANTD2,SLC6A15,ZMAT4,REV3L,TTLL7,SETD5,RAVER2,TMEM100,NEK11,TCP11L1,STK32B,LRRK2,LGR4,ATAT1,CLIP1,NCBP3,FAM192A,SATB1,ATXN7,SCN2A,LINC00461,SCP2,FNIP1,ELMOD1,SLC30A10,SFPQ,SUPT20H,COPZ1,HSPA4L,SGK1,ITSN1,DOCK10,NTNG1,CHD9,R3HDM2,ST3GAL3,SEC31A,FAM81A,SLC1A7,URGCP,CCDC88A,SLC14A1,ATF7IP,TET1,CPEB4,RCOR3,ANKRD36,LIMCH1,RIMS1,MBD5,LMBRD1,SNRPN,RBM34,SON,PDZD2,MYT1L,SOX5,KDM3A,SP4,RBM26,NPAS3,LMO3,TAB2,ATP10B,CLASP2,POGZ,ITPRID2,ZNF302,NKAIN2,MAPK8IP3,ZSCAN29,TTBK2,KANK1,SULF2,STXBP1,AJAP1,KLHL7,FNDC9,PLCB1,SYT4,TAC1,MTCL1,CAMSAP2,FAM208A,ADGRL3,TBCEL,FBXW11,TCF4,SIN3B,TCF7L2,ZEB1,TCF12,RALYL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,SIRT1,TIAM1,ZFP91,ERCC6L2,KAT6B,METTL3,TSN,TSC1,RFTN2,CADM1,RPL7L1,WIPF1,LAT2,CLDND1,RICTOR,SF1,ZNF711,ZNF19,MICU3,KCNT2,ANKS1B,SMARCAD1,SYNC,WNK1,EMSY,MFF,SLC17A6,FAM13C,MRPL47,PHTF2,CAMK1G,NUP214,JMJD1C,NLRP3,ZNF248,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-323-3p:mirSVR_highEffct hsa-miR-323-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-167 6.35E-164 7.05E-166 6.50E-165 363 1280 "ACADM,ABHD6,ADD1,BRAP,SORCS1,PWWP2A,DPY19L2P4,NLGN4X,SLC44A5,ZNF608,MTUS1,KLHL13,HACE1,TBC1D14,OSBPL8,C1QTNF3,ALCAM,FAM135A,CDC42BPA,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,GPAM,ALS2,APP,SHTN1,CDC14B,MIER1,MADD,DDX3Y,ATP1B3,NOL4,DST,SYNJ1,SYNJ2,ARHGEF7,MTMR2,JAZF1,SGCE,GPC2,IL33,MMD2,CA8,KALRN,PTBP2,CERS5,C1orf52,LRBA,CDC27,CDH10,LGI1,RCBTB2,SRSF11,CHM,CNOT8,JAM2,NDST3,NRXN3,CLCN4,NRXN1,NIPBL,FHL5,SLC4A8,ZNF521,ENTPD4,RBM39,CRMP1,ATRNL1,APPL1,PHF14,NRSN1,PUM1,RIMS2,ST18,CX3CR1,DOCK4,HDAC9,KATNAL2,GAPVD1,RIPOR2,TOX,DAPK1,BRINP1,ELMSAN1,DNAJC6,ZNF804A,C8orf34,ZEB2,HP1BP3,FBXL5,NTM,G3BP2,WDR20,CDON,DMTF1,CASP8AP2,ABI1,PDCD6IP,RCAN1,DTNA,ECM2,DNAJB6,GOLT1B,E2F6,EDNRB,ANKRD46,HIPK3,SEMA3D,FRY,YAF2,PHF20L1,EGR3,LPAR6,EIF4G2,TENM1,ELAVL2,ELAVL4,TMEM35A,EIF1,SEZ6,EPHA5,KCNMB2,ENPP6,SH3YL1,ACSL4,SCML2,SLC9B2,POLR1B,SUCO,UBE2E3,MEX3B,SEC23B,PCYOX1,IQCG,FLT1,C2orf88,EFCAB2,ATP6V1H,ATP2C1,PNMA2,MSANTD4,PHYHIPL,STAG2,GABRB1,GABRG1,GAD1,GAD2,ARPP21,NEK6,ERAP1,KIAA1841,ARFIP1,SESN1,TCERG1,MSL3,PCDH11X,GNAS,FERMT2,ADGRA3,TDRKH,GPR22,GRIA4,SPACA9,GRM7,TMEM25,LINC01551,SOX21,MAP4K5,ARHGAP19,HNMT,ZNF491,HNRNPK,MSL1,IDH3A,ZNF181,C5orf24,ZIC5,RBPJ,LRRCC1,IL11RA,ZNF385B,SLC35G1,METTL21A,OLFM3,KCNQ3,KIF2A,IPO5,STXBP5,CYP27C1,LMO1,VWA5A,HECTD2,MARK1,LYPLAL1,MAT2A,MITF,ZNF680,SESN3,MTTP,MXI1,NAP1L2,NAP1L3,SLCO1C1,NFE2L2,NOVA1,SMIM11A,HCN1,PCDH8,PDE4B,PDE4D,PIRT,PLCL1,PMP2,RC3H2,LRP12,PSAT1,ING3,SH3KBP1,MED1,MINDY2,PPM1B,CRLS1,PPP2R5E,RANBP3L,PKN2,HYDIN,DIRAS2,VPS13C,SNRK,CNTLN,ANKHD1,TMEM260,OCIAD1,PTPRZ1,PEX5,MARCH1,SLC25A48,USP47,SUSD4,RAP1GDS1,ENOX1,RASGRF1,RBBP6,RADX,KHDRBS2,SLC6A15,NUDT11,PBRM1,ZFHX4,EXD2,ALG9,ROBO1,PCMTD2,BAALC,SPIN3,ATP8B4,TCP11L1,LRRK2,LGR4,RMI1,SEMA6D,CSRNP3,SCN2A,LRRTM4,SCN8A,FNIP1,SUPT20H,SGK1,SH3GL3,ARX,CPEB3,CHD9,SLITRK3,ZNF365,RUFY2,KANSL3,SPHKAP,CPEB4,COA1,ANKRD36,SNCA,MBD5,LMBRD1,PALLD,UNC80,USP33,PDZD2,MYT1L,SP4,ZNF423,SPTB,KIF1B,RBM26,NPAS3,RAP1GAP2,LMO3,SRPK2,PBLD,ZNF302,ZC4H2,LRRC4,ERBIN,ZSCAN29,NEK4,COBL,SYT4,ATP11A,PJA1,CAMTA1,ADGRL3,FBXW11,SATB2,ZFP90,PCDHB15,PCDHB7,GPRIN3,SIK3,ZFPM2,AP4E1,SLC44A1,TJP1,DDHD1,ZFP91,ERCC6L2,TMPO,FAM124A,NPL,DCBLD1,TSN,ANKRD20A2,PRR18,TMEFF2,SLAIN1,CCDC14,VSNL1,ZNF781,RICTOR,ZIC2,ZNF711,MICU3,TRIM9,MKRN3,REEP1,ANKS1B,FTSJ1,PLPPR5,WNK1,EMSY,STOX2,ADAMTS9,WNK2,SLC17A6,FAM13C,UBE3B,SMIM8,CASC15,ACTR3B,JMJD1C,ZNF248,GAN,SENP7,JPH3" MicroRNA hsa-miR-514:mirSVR_lowEffct hsa-miR-514:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-167 6.58E-164 7.23E-166 6.66E-165 419 1715 "RALGAPA1,CLK4,CSMD3,KLRC4,TMCC3,BRAP,PNMA8B,KIAA1211,BEND6,AP2A2,MTUS1,KLHL13,PCDH19,HACE1,WDR35,LRRC7,SEMA6A,ALCAM,MARCH4,PCDH10,BBOX1,UNC79,FAM135A,GPRASP2,LRCH2,ANK3,C6orf89,LCORL,PPFIA2,PPFIA1,PKP4,ANXA7,UPRT,NT5C3B,PHYHD1,USP37,AQP4,PPP4R4,RGS20,CADPS,LINC00173,ASPH,TMEM108,ATP1B3,ATP2A2,ALDH7A1,ADAM23,LINC00847,BCHE,DNAJC27-AS1,BMP7,SCAPER,C5,IL33,CA12,VSTM2A,ISPD,CLDN10,USP6,MTMR7,AIFM1,TMEM257,REPS2,CDC27,CDH8,MAGI1,SOCS6,CASC2,MS4A7,SYNPR,RAB3C,CNOT8,C7orf61,IGLON5,ARMC8,AKAP6,MAGED1,ZNF521,FAM171B,PNKD,C2CD2,CREM,GDA,SNCAIP,RGS6,LRIG1,ARHGEF10,MICAL2,VCAN,PPP1R16B,ERC2,APPL1,PUM1,ECE2,FGFR1OP2,KATNAL2,RIPOR2,DCAF8,MATR3,GIT2,DNAL1,DCC,JAKMIP2,HEPH,FBXL5,GSDME,SGSM2,DLX1,EXOG,SLC29A4,DMTF1,DPH1,DRD1,DTNA,TOM1,ABCC5,DNM1L,EDN1,EDN3,ATL1,FCF1,SEMA3D,TMTC1,FSD1L,SH3GLB1,ABI2,EIF5,MRNIP,EML1,CALCRL,EIF1,EMX2,RCAN2,DENND4A,NCALD,ZNF549,MRPL37,KATNAL1,TAOK3,FCGR1A,CEP78,FDFT1,ZNF589,PRKAG2,CAMSAP1,MEX3B,SGIP1,EFCAB2,SMC2,ATP2C1,KHDRBS3,ABLIM2,OGA,DKK3,MEGF10,GAB1,GABRA1,GABRG2,HBS1L,ZNF234,SYT17,C15orf41,DISC1,ATP8A2,INPP5K,IGSF5,GCNT2,MSTN,ADAM28,GFRA1,GK,GLDC,TNRC6A,ZNF638,GNAL,GPD2,PRUNE2,GPM6A,LILRA1,CCDC184,GPR22,GPR34,PCLO,RAPGEF4,GRID1,RFFL,GRIN2C,GRM5,GRM7,FAM19A2,ZBTB49,MFSD2A,WIF1,ZHX1,FRMD5,PTGDR2,HRH3,BACH2,ELOVL5,TLX1,HSPA1L,MSL1,ZNF546,LRRC25,RBPJ,DOCK7,OLFM3,KCND2,KCNMA1,KIF5A,IPO5,STXBP5,LAMA2,STMN1,INSYN2,SFXN5,SYTL4,LSS,MBD1,MBNL1,SYT9,LRP1B,WDR49,ZNF680,CTNNA3,HS6ST3,MYT1,HNRNPM,NAP1L2,NASP,NDUFA5,SFR1,NEFH,NOVA1,NPTX1,SLC11A2,NUCB2,OCRL,CHAMP1,OMG,SNTG1,PAK3,DPY19L2P2,PCDH8,PCMT1,PDE1C,PDE4D,PDGFRA,PDYN,SLC10A4,BEST3,SERPINI1,NOMO2,XRN1,PLCB2,C11orf49,PDZRN4,PRRX1,ING3,NXPH1,PPP2R2B,CRLS1,PPP3CB,PRKAB2,PKIA,PRKAR1B,PRKCB,PRKCZ,MAPK4,MAPK8,MAPK9,PRPSAP2,VPS13C,CNTLN,PLPPR1,BDNF-AS,MTMR10,PTPRE,PTPRN2,PTPRO,RALGDS,FAT4,RADX,REV3L,RFX4,RGS3,RGS7,TTLL7,RIT2,RIC8B,RPE65,NEK11,RPL15,ZNF671,ACER3,LRRK2,CNTNAP3,ATAT1,ZNF568,TRAPPC13,SEMA6D,SCN2A,SCNN1D,SLC30A10,SOX6,SUPT20H,TRA2B,SCG5,ITSN1,PPM1E,CPEB3,FHOD3,ST6GAL1,ST3GAL3,PPP4R3A,SLC6A1,ZNF430,SLC8A3,SLC9A5,TMEM132D,SCMH1,ATF7IP,SLCO1A2,IFT122,ANKRD36,SNAP25,MBD5,LMBRD1,SNRPN,USP33,WDTC1,MYT1L,ZSWIM8,SP4,MYCBP2,TEX2,ZNF423,ZBTB43,RBM26,TAB2,POGZ,SAMSN1,EPB41L3,LRRC4,SSPO,ERBIN,MAPK8IP3,ZSCAN29,CEP68,PHLDB1,KANK1,SYPL1,TACR1,ANKRD12,KAZN,PJA1,MLST8,TAL1,UNC5D,ACSL6,TCF4,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,SIRT1,CRB1,AP4E1,SLC44A1,TIAM1,RELL2,BHLHB9,BEX4,CSMD1,PIK3R5,TP53BP2,SYNPO2,AMACR,KCNE5,ANKRD20A2,TTC3,GORASP1,BCL2L13,RICTOR,GUSBP1,ZBTB14,ZIC1,ZNF708,KCNT2,GPR158-AS1,TCEAL7,DPYSL5,CA10,EMSY,MFF,SLC38A1,LINC02210,HPS4,SLC17A7,C12orf4,PDSS2,RTN4,SMIM8,FBXO36,KLHDC1,PIANP,FRMD6,IFT88,NETO1,SLC4A10,GAN,FAM198A" MicroRNA hsa-miR-1226*:mirSVR_lowEffct hsa-miR-1226*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-167 1.28E-163 1.39E-165 1.28E-164 448 1961 "DPF1,CPNE2,SYN3,ACHE,SYS1,GPRIN1,TMEM132B,GALNT16,ADCY6,ADD1,ADD2,SLC12A5,PTCHD1,ADRA1D,AP2A2,ZNF608,RTL9,CARNS1,AMPD2,KIF6,ZFAT,CDC42BPA,EP400,FGD2,C6orf89,CCDC146,APBA2,DGKZ,UPRT,MIER1,CDK13,MARCH3,MARK4,ZSCAN18,TMEM108,ATP6V0A1,ADAM23,BCL2L2,CFLAR,JAZF1,BAIAP3,IL33,BTRC,CFAP410,CA4,CACNA1A,CACNA1B,CACNB4,CABP7,CAMK2G,TRIM41,CAPN3,CAST,HIP1R,MAP7,CLDN10,P2RX6,SEPT7,ZBED1,DCLK1,LARGE1,FOXN3,ASIC3,PLEKHB1,TAOK2,RAB33A,CLCN3,DGCR9,TJP2,FADS2,MAP4K4,IGLON5,CNN3,ARHGEF6,AKAP7,AKAP5,SLC4A8,CNRIP1,MFSD4A,SLC35F1,PNKD,PREPL,CREM,HINFP,CSF1,TENM4,CSF2RA,SEC24C,ARHGEF10,CSNK1E,ATRNL1,NCAN,CNTNAP2,DZIP3,SDC3,GREB1,CFAP61,CTNND2,RIMS2,EDRF1,CX3CR1,ECE2,CYBB,HDAC9,GAPVD1,DCAF8,CENPL,INTS1,IST1,TOMM20,SCRN1,IP6K1,DBI,PLEKHM1,HP1BP3,RUSC2,C2CD2L,POM121,SV2A,SGSM2,KIF19,DLG2,HS3ST2,RPS6KL1,DNM2,SHANK1,DMTF1,DPH1,SLC25A18,GNE,DTNB,TOM1,FARSB,EDNRA,FAM13A,APH1A,EGFR,EIF4G2,PLEKHA1,STARD3NL,COQ7,ENPP6,STX2,MRPL37,SRARP,RASL12,ZNF461,TUBA1B,PTK2B,ZIC4,CHST15,TOMM40L,FKTN,KAT8,ZNF589,FGF1,FGF12,FGF13,FGFR1,BAIAP2,TMEM164,FOXM1,PSD2,FOLR2,DPYSL4,TMEM107,SMC2,ZNF605,ERGIC3,NSG2,DACH2,STAU2,KBTBD12,DOT1L,BRSK1,OGA,GABRA3,GAD1,B4GALNT1,ARPP21,ERAP1,DISC1,TUBGCP4,MSTN,CYP46A1,GFAP,GFRA1,GFRA2,USP19,ZNF276,TNRC6A,GLUL,ZNF638,CBX1,DCLK2,LOXL3,GOLGB1,PRRC2B,GPM6A,FUT10,CCDC184,ADAP1,CNTRL,GRIA1,RFFL,ADAMTS13,RNF165,PTPN5,AP4S1,SLC2A6,MAN1B1,HRH3,TNFAIP8L3,MIER3,HPSE2,SYNPO,HNMT,CPT1C,HSD17B1,HSPA1L,LINC00667,RAB41,NKD1,GAREM2,ZIC5,USP54,IGSF1,ITPKA,KCNA6,KCNC1,KCNJ5,KCNK3,KCNN2,CREG2,KLRC3,A1BG-AS1,L1CAM,LRRC4B,LAMP2,SFXN5,MAG,MAN2A2,ZFYVE27,MAP4,AQP11,MBD1,SYT9,TM6SF1,MEF2C,MPP2,ERICH3,CPNE9,ADAM22,NRBP2,MX1,LYRM9,MYO7A,NAP1L2,NCAM1,NDUFA5,CCDC13,NF1,OTOGL,NME4,NOS1,DNHD1,PCBP3,SMIM11A,NTRK2,NUCB2,IGSF11,ZDHHC22,PAK3,CNTN3,PCSK1,CDK18,PDE4D,BEST3,CYTL1,PFKFB2,GDAP1L1,CAMKV,PIK3R1,SNX10,ZFYVE21,PLEC,FTO,SMIM7,PLTP,ASPDH,C11orf49,ING3,RETREG2,SEPT4,FA2H,NXPH1,CRLS1,PRKCZ,DIRAS2,NDUFS7,WBP1L,MDGA2,PIGG,CNTLN,NCR3LG1,BDNF-AS,MTMR10,TMEM260,FAM120C,PEX5,PPP2R3C,SLC25A48,USP47,CCDC40,RAD52,RASGRF1,RFX4,RGS12,KCTD17,KIF7,RNF220,RIC8B,CCDC82,C12orf49,RAVER2,CARF,PCMTD2,ATP8B4,ACER3,KCNIP3,CLIP1,STX1B,NCBP3,SEMA6D,DRAXIN,SCN2B,LRRTM4,SCP2,ASIC4,ELMOD1,IL17RB,SFPQ,COPZ1,FAM102A,KIF16B,NTNG1,AMBRA1,FNDC3A,PAAF1,SLC1A3,SLC6A1,PKNOX2,SLC6A9,SLC8A2,SLC8A1,SLC8A3,SIRT2,SLC11A1,SLC12A4,ZNF334,SLC14A1,ELMO2,SLC20A2,ANKRD36,MAPKBP1,PALLD,FAM126B,UNC80,RBM34,KDM4B,SCN3B,SON,FNBP1,ZSWIM8,PEG10,SPTAN1,IQSEC2,ZBTB43,DDN,SPART,NFASC,EPB41L3,MAPK8IP3,NEK4,SEPT3,SYT11,JMJD6,VAMP1,SYN2,SYP,MMS19,CAMTA1,PDLIM2,CNTN2,ADGRL3,SMG6,NEU4,KIAA0930,TCF12,SYNE1,PHF24,TNS2,HIF3A,TEX15,CYB561A3,RNF216P1,ATP13A2,TF,DICER1,CRB1,AP4E1,THRA,ERCC6L2,C5orf64,TNS1,CDK20,RGMB,SYNPO2,SMUG1,TRO,STXBP4,TRPS1,TSC1,ZKSCAN5,UBE2H,GORASP1,OSBP2,FLRT1,BEST1,TSPAN11,NSD2,ZBTB14,TRIM9,CELF4,FSTL5,ZNF184,ZSCAN26,WNK1,PRDM2,LMAN2L,SLC17A6,DOCK8,KAT6A,TMEM63C,ZNF248,TIGD6,GAN,PRRT4" MicroRNA hsa-miR-3190-3p:mirSVR_lowEffct hsa-miR-3190-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.26E-167 1.83E-163 1.97E-165 1.81E-164 429 1802 "SYS1,SLC25A25,DSCAML1,SLITRK1,GALNT13,DISP3,HFM1,CARNS1,AMPD3,ANK1,EP400,PPFIA1,ANXA7,PARG,APAF1,APBB1,KCNAB2,MAGEE2,DGKZ,TNRC6C,SHTN1,CDK13,ZBTB10,DDX3Y,ALDH4A1,ATP1A2,SLC2A11,RIPK1,ADGRB1,LINC00847,DNAJC27-AS1,DCAF5,CFLAR,KSR1,CDK5R1,SYNJ2,MTMR2,JAZF1,WASF1,CACNA1E,CACNG1,KALRN,PTBP2,CAMK2D,CH25H,RHBDL1,SPAG9,NFS1,ZNF501,SHISA7,KYAT1,CD38,NEURL1,LRRFIP1,CDO1,TIGD7,NUMBL,CBARP,SOCS6,TAOK2,DLGAP3,CPNE6,RAB33A,NRXN3,CLCN4,CLTA,QKI,SULT4A1,TMEM155,IGLON5,CNTN1,AKAP6,COL9A3,TOGARAM2,MFSD4A,SLC35F1,CLOCK,CREB5,ANKRD44,NCOR2,SIPA1L1,PDE4DIP,PPP1R16B,GREB1,CTNND1,DCAF4,RUBCN,ECE2,HDAC9,DCAF8,FRMPD4,ZFYVE16,LONRF1,KIAA0586,MAML1,TMEM170A,PABPC5,DCT,KIAA0753,COPS7A,C2CD2L,GUCD1,SV2A,SRGAP3,AK5,TMCC2,WDR20,OLIG1,SLC29A4,SLC25A18,DTNA,ECM2,FAM78B,TOM1,ABCC5,CNNM1,TMTC1,SH3GLB1,GPR61,SUGP2,ASB3,SORBS3,IRAK4,ELAVL3,C3orf18,TMEM35A,CALCRL,PAN3,EPB41L1,RASGRP2,EPHB1,EPS8,ERBB2,DUSP27,SIRPB1,GMPR2,MRVI1,F3,FAM198B,SH3YL1,CACNG2,TUBB4A,TAOK3,ATP8A1,CEP78,FCGR3A,TOMM40L,TESK2,SLC9B2,FER,FHL1,POLK,SYNCRIP,FOXM1,ANKFY1,EFCAB2,WDR83,USP21,CAMKK2,KHDRBS3,DACH2,PNMA2,B3GAT1,HHIPL1,NRG3,MPP6,STAG2,HRASLS5,CHL1,GABRB3,CAB39,B4GALNT1,IP6K3,NCKAP1,ZNF559,ATP8A2,TUBA8,ARFIP1,GPR162,USP19,GGT7,TTBK1,GLYR1,RAB30,GLRB,MSL3,STARD3,DCLK2,LOXL3,CNDP1,GPD2,GPR12,CCDC184,NUDT21,EML4,RAPGEF4,RAPGEF1,PLCD4,GRM3,GRM7,ZNF496,RNF165,ZBTB49,AP4S1,RABL2A,SOX21,ATOH8,CELF3,TOX2,PADI2,NXPH3,CPT1C,TCEAL6,HSD17B1,LRRC75A,ICA1,MYLK2,IGF1,SCIN,ITPKA,ITPKB,JAK2,KCNA6,KCND2,KCNJ3,KCNJ10,KIF5C,IPO5,KTN1,CAMK2N2,LIG4,VWA5A,PACRG,MAP6,AQP11,ADAM11,MDFI,LDLRAD3,MGAT3,WDR49,ERICH3,ZNF680,MSR1,NRBP2,MYH6,PABPC1L2A,FXYD6,NDUFA5,RCOR2,NINJ2,NME4,NOVA1,LRIT2,SLC11A2,SMIM11A,NUCB1,NUCB2,NUMA1,OGG1,OLR1,ZDHHC22,PCDH9,CDK18,PDE2A,CAMKV,GPSM2,PLP1,CDIP1,STRN3,TNPO2,POU6F1,PPM1B,KANSL1,RASGEF1B,PRKACB,MAPK3,EPDR1,MAPK9,MASP1,RELN,BCAS3,WDR25,CNTLN,PXK,TMEM260,PTPRE,CASTOR1,PTPRZ1,ZSCAN2,TTC13,TUG1,ZNF844,RALGDS,ENOX1,ARID4A,RADX,RET,RGS12,TTLL7,RNF220,RIC8B,TMLHE,ARMC5,NEK11,SGSM1,ATAT1,SAFB,SEMA6D,ATXN7,PRCD,ELMOD1,IL17RB,SELL,HSPA4L,SGK1,KIF21A,ARX,KIF16B,NTNG1,AMBRA1,FBXO11,RPH3A,SMTN,RUFY2,PKNOX2,SEPHS1,RADIL,SLC20A2,SPHKAP,MYH15,IFT122,RIMS1,KIF13A,LMBRD1,TMCC1,UNC80,KDM4B,DOP1A,SON,WDTC1,DOK5,ZHX3,ZSWIM8,NMNAT2,TSPYL2,RBM26,NFASC,LMO3,SRPK2,TAB2,POGZ,COLGALT2,STOX1,SAMSN1,ZC4H2,LARP4,SS18,SSPO,MAPK8IP3,KLHL7,FGD4,JMJD6,ZFR2,FNDC9,DNAJC9,SYPL1,SYT5,CAMTA1,ADGRL3,WWC1,WSCD1,ZEB1,AZIN2,DOCK9,AHCYL2,DICER1-AS1,KHDC1,CRB1,AP4E1,HHIP,THRA,TMEM9,DDHD1,DAAM2,RIMBP2,R3HDM1,TNR,TNS1,RASD2,TPM2,TPM4,RGMB,STXBP4,KCNE5,TTC3,ZKSCAN5,FAM155A,UBE2H,UBTF,ZNF709,LMF1,RBFOX3,NPDC1,SLC13A3,LGI4,ZIC2,ZNF28,TRIM9,FMN2,ZNF138,CELF4,ZNF142,POLR3H,EML6,TFIP11,SYNC,MFF,PRDM2,ADAMTS9,PCDH15,SNX27,FIP1L1,SLC17A6,PARP11,EPM2A,SMIM8,RNF170,PIANP,NETO2" MicroRNA hsa-miR-489:mirSVR_lowEffct hsa-miR-489:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-167 3.08E-163 3.28E-165 3.02E-164 436 1863 "CLK4,EMILIN3,NBAT1,XKR4,CSMD3,ADCY6,ADD3,PTCHD1,FAHD2CP,SLC44A5,ZNF608,INTS2,PCDH19,TXNDC16,ZNF578,BCAR3,ARHGAP20,PCDH10,BBOX1,GPRASP2,AMPD2,DPP10,KCNAB2,VAT1L,AMER3,MIER1,IGDCC4,SPTBN4,ASCL1,MARCH3,ASPH,NUMB,CCAR2,TMEM108,ATP1A2,ATP2A2,NOL4,RIPK1,ADAM23,SNAI3-AS1,BCHE,BMP7,NAE1,SCAPER,MTMR3,MTMR2,MMD2,CACNA1B,LURAP1,CAMK2D,CAST,ISPD,MTMR7,P2RX6,CD86,TMEM257,LRBA,CDH8,CDH10,LGI1,CDO1,TIGD7,GPR37L1,ASIC3,PLEKHB1,SYNPR,CNOT8,NRXN3,ZFYVE9,NRXN1,CLU,SULT4A1,MAP4K4,NIPBL,CNR1,COL4A5,SUMF2,SLC4A7,CP,CHD1L,FAM171B,CLOCK,C2CD2,CREB5,HAPLN1,CRY2,ANKRD44,CSF2RA,SEC24C,VCAN,CST3,PNPLA8,CTH,PUM1,RIMS2,DCAF4,USP6NL,HDAC9,FGFR1OP2,TOX,ACY3,MATR3,DGKB,DAPK1,IP6K1,AIF1L,DCC,SPATA2,DNAJC6,ZNF804A,ZEB2,HEPH,MYEF2,TIAM2,MAGI2,KLHL3,BLOC1S6,LYPD1,SV2B,NTM,G3BP2,FAM107B,DLG3,DLX1,CD99L2,NR1D2,CASP8AP2,DYRK1A,E2F5,E2F6,FAM135B,PHC2,ANKRD46,HIPK3,TMTC1,FAM13A,KMT5B,ABI2,AASS,ELAVL4,STARD3NL,EPHA5,KCNMB2,IGSF6,SPEG,MRPL37,MRPL10,MRVI1,ABCA8,ATP8A1,SEC24B,FER,UBE2E3,MEX3B,SYNCRIP,NOP56,PDLIM5,ST6GALNAC3,MEGF11,GABRA1,GABRA5,GAD2,HBS1L,BRPF3,ZMYND11,C15orf41,MYOZ2,GATM,GCNT2,MSTN,GLYR1,TOX3,PCDH11X,ZNF638,HTATSF1,MAP7D2,GNAL,LNX1,ADGRA3,LILRA1,LPAR4,NUDT21,GRB10,GRIA1,GRIA2,GRIA4,SERP2,GRM7,GSN,MFSD2A,SOX21,MAEL,HPS5,ZHX1,MIER3,ELOVL5,NEGR1,SHISA6,HTR5A,ATCAY,IFI16,ZNF181,SOWAHA,C5orf24,IGFBP1,DOCK7,BRINP3,DIPK1A,ITGAM,SLC35G1,KCNC2,KCND2,KCNK1,STXBP5,CYP27C1,INSYN2,SFXN5,LIMS1,VWA5A,PACRG,GPR155,NAT8L,MARK3,MBP,SYT9,LDLRAD3,MDM4,MEIS1,SCAMP5,MMP16,MOG,MSR1,MYO5A,RTL5,NAP1L1,NEFH,NELL2,NFE2L2,VWA2,DNHD1,NTRK3,PCDH9,PCSK1,PCSK5,PCSK2,PDGFRA,PDPK1,GNG2,PFKFB2,PFKFB4,GDAP1L1,ANLN,PKM,FAM216A,SLC25A23,HMGCLL1,PURG,SCHIP1,ING3,CRLS1,PPP3CB,PRKCB,RAB39A,PKN2,MAPK9,MASP1,LRRC49,PTK2,STK32A,ZIK1,PTPRG,RAB3A,ZNF793,FAT4,RASGRF1,RADX,BSDC1,RFX5,RGS3,RGS4,RGS12,PRIMA1,SEC61A2,RPRD1A,TMLHE,RORB,PCMTD2,CCDC102B,RPE65,SNX22,GLDN,ACER3,LGR4,SYNDIG1,ATAT1,KCNIP3,NCBP3,CCDC112,AP1AR,SEMA6D,HOGA1,SCN2A,SCP2,FNIP1,ASIC4,ELMOD1,SOX6,ZNF821,FOXRED1,SFPQ,MRAS,NLGN4Y,ITSN1,PPP1R9A,PPM1E,FERMT1,DOCK10,SHC4,CHD9,FNDC3A,FHOD3,ST6GAL1,NUBPL,ABLIM3,SLC1A3,SLC2A5,WDR47,SLC6A8,RAB3GAP1,SLC11A1,SCMH1,ELMO2,EFHD1,ATF7IP,SLCO1A2,CPEB4,RCOR3,IFT122,ANKRD36,KIF13A,UNC80,USP33,TRERF1,BDP1,NMNAT2,SPP1,TEX2,NPAS3,NFASC,CLASP2,LRRC4,NXT2,PHLDB1,STX1A,KANK1,NECAB1,TMEM150C,SYP,SYT1,TACC1,PJA1,FBXW11,TCF4,TCF7L2,TPCN2,TRIM2,RALYL,PCDHB7,FRYL,SIK3,DICER1,SIRT1,CRB1,AP4E1,ARL10,HEY1,ACTR6,DDHD1,TLR4,NR2E1,DAAM2,TNFRSF1B,C5orf64,TNS1,TRO,STXBP4,FNDC5,ANKRD20A2,TTPA,ZKSCAN5,WIPF1,CLIP2,ETNPPL,XPO1,SF1,ZBTB14,ZNF24,TRIM9,FMN2,NDRG4,SLC26A10,MKRN3,LYPD6,POLR3H,FSTL5,DPYSL5,ZFAND5,SMARCAD1,DHX33,WNK1,EMSY,CADM2,RGMA,GDPD5,LINC02210,PRDM8,PRDM10,ADAMTS9,MDH1B,PCDH15,TMEM163,FAM47E,GOPC,ST7,UBE3B,SMIM8,HNRNPA3,FBXO36,CERS6,JMJD1C,ZNF248,TIGD6,RNF170,KLHDC1,RNF146,GAN" MicroRNA hsa-miR-433:mirSVR_lowEffct hsa-miR-433:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.05E-167 5.08E-163 5.35E-165 4.93E-164 424 1765 "KCNH8,AS3MT,C3orf14,KDM5D,ADAR,TMEM132B,TMCC3,AXIN2,SORCS1,USP31,ADRB2,KIDINS220,BEND6,SLC24A4,PCDH19,OSBPL8,CC2D2A,PLA2G6,LRRC7,SEMA6A,ALCAM,LRCH2,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,UPRT,ALS2,AMER3,BCAS1,TNRC6C,SHROOM2,CADPS,CAPRIN2,BRINP2,SLC4A4,ATP2B3,DPY19L3,ATP6V0A1,ADGRB3,ZNF599,PROM1,BMPR1B,DST,NAE1,NIPA1,BTRC,CA8,CACNB4,KALRN,CAMK2B,SYT6,CBR1,CBS,USP6,MTMR7,NEURL1,C1orf52,CD81,ZBED1,CDC42,L3MBTL4,LOC730101,MAGI1,CCPG1,CFL2,FOXN3,ASIC3,CASC2,SYNPR,ZBED5,JAM2,SLIT2,NRXN3,CLCN3,CLTC,FBXO7,FAM19A5,QKI,HECTD1,FHL5,CNN3,AKAP7,COL9A1,SMARCAL1,BAG4,ANKRD44,CLIP3,CRYM,CSF1,MICAL2,OSBPL3,ATRNL1,IPCEF1,PDE4DIP,APPL1,PHF14,PLCXD3,CTH,KIAA0408,GPRASP1,ARHGAP32,ZNF337,KCTD8,TMEM170A,TOMM20,PABPC5,BRINP1,DNAL1,ARMCX2,C8orf34,FBXL5,KIAA0319,TMEM130,FBXO25,DDX46,PLPPR4,SRGAP3,MTX3,HS3ST4,NR1D2,DOCK2,EDIL3,EDN3,EDNRA,ATL1,HIPK3,TMTC1,FSD1L,YAF2,SH3GLB1,PHF20L1,MRO,TENM1,ELAVL4,EML1,EPHA5,ANKRD13B,ETV1,SIRPB1,EYA1,ARMCX1,FABP7,TUBB3,DLC1,CEP78,FCGR3A,ZSCAN30,FGF1,OLFM1,FGF11,FGF13,POLK,FOXG1,SYNCRIP,ANKFY1,SLC37A3,AFF2,C2orf88,TMEM175,NBEA,SORBS1,USP16,UFM1,FAM49B,ZNF605,STAU2,KBTBD12,AP4B1,NRG3,TVP23A,OGA,FYB1,MEGF10,GABRA1,GABRA2,HRASLS5,HBS1L,ARPP21,GALR1,NEK6,ATP8A2,LRRC37A6P,KIAA1841,SULT1C4,WASHC2A,ADAM28,MALT1,GJB1,TXNL4A,HPGDS,PCDH11X,GPT2,ADGRA3,LILRB4,PRUNE2,FUT10,STON1,GPR22,PCLO,STMN2,PLCD4,PLPP7,RFFL,ADAMTS13,CACFD1,GRM2,RABL2A,ADAMTS6,GUCY1B1,SLC2A6,MAP4K5,ATOH8,HAS2,UBE2QL1,HPS5,TOX2,PACSIN2,MAN1B1,LINC01102,HLF,ELOVL5,NEGR1,CELF5,IRF8,IDH3A,SOWAHA,IGF1,LRRCC1,USP54,IGSF1,INSM1,LRRTM3,KCNC1,KCNC2,KCNK1,KCNN2,KIF5A,LIG4,LMO2,GPR155,MARK1,MATN3,MBD1,MBNL1,MBP,CHIC1,MEIS1,MEIS2,AFDN,MOBP,SAMD5,CCDC80,N6AMT1,ZNF862,NAP1L3,ZC3H12B,NELL1,VWA2,NOS1,CNOT4,NPY,NOVA1,IGSF11,CHAMP1,OPHN1,CLDN11,KCNK10,GLIPR1L2,PAK3,PAX6,PDE1A,PDGFRA,PFKFB2,OLA1,DUSP26,PIK3C2A,ANLN,PIK3CD,RETREG1,MTRF1L,PLXNB3,SCHIP1,PRRX1,POU6F1,CRLS1,RASGEF1B,PRKCB,MAPK9,VPS13C,LRRC49,MDGA2,TMEM260,PTPN13,PTPRB,PTPRD,PTPRN2,PTPRO,NKAIN1,ZNF615,SLC25A48,USP47,ZNF793,SH3TC2,SUSD4,RASGRF2,ARID4A,KHDRBS2,SLC6A15,ZDHHC4,SLC25A36,PBRM1,RPRD1A,ZFHX4,TMLHE,ALG9,GSTCD,RORB,ARMH4,GLDN,PRR5L,LRRK2,LGR4,WLS,TRAPPC13,DGLUCY,SARS,ATXN2,SCN2A,FAM19A1,SCP2,SOX6,ZFP30,ASAP3,DOCK10,FNDC3A,FHOD3,ST6GAL1,ST3GAL3,SLA,ZNF365,BTBD3,EPN2,KANSL3,RAB3GAP1,SLC14A1,SLC15A2,TET1,SLN,SMARCE1,ANKRD36,MBD5,CMTR2,LMBRD1,NMNAT2,UHRF1BP1L,SPP1,TSPYL2,C11orf87,ITPRID2,SST,NXT2,ZSCAN29,KANK1,AJAP1,GSE1,SYPL1,ATP11A,TACR1,TAL1,CAMSAP2,TBCEL,VWA3A,ACSL6,DMXL2,TRIM2,CLASP1,SZT2,SYNE1,PCDHB10,NSD1,ARHGEF12,USP32P1,HIF3A,ATP13A2,CRB1,C18orf54,AP4E1,SLC44A1,TIAM1,KAT6B,NPL,DOK6,SYNPO2,AMACR,TRPC3,TRPS1,TSN,ANO5,SSBP2,RFTN2,TMEFF2,SLAIN1,VAV2,MEAF6,CCDC14,SF1,ZNF28,MKRN3,AMZ1,ZSCAN26,CADM2,PRDM2,LINC02210,STOX2,ADAMTS9,TMEM178A,GAL3ST3,NAV3,SNX27,FAM13C,KAT6A,IFT88,NETO1,SLC4A10" MicroRNA hsa-miR-182:mirSVR_lowEffct hsa-miR-182:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-166 1.01E-162 1.06E-164 9.73E-164 445 1945 "KCNH8,CLK4,NBAT1,KDM5D,PLEKHG5,ADD1,BRAP,PLEKHH1,GRAMD1B,USP31,PWWP2A,KIAA1211,SNX30,BEND6,OLMALINC,KLHL13,HACE1,KIAA1324,OSBPL8,CC2D2A,TAOK1,SEMA6A,PCDH10,GPRASP2,SYT13,AMPD2,AMPD3,LRCH2,ANK2,UPRT,ALS2,VAT1L,BCAS1,AQP4,MIER1,CASK,ARHGAP5,STK33,ATM,SLC4A4,ATP2A2,ATP2B2,DPY19L3,ATP6V1G2,BACH1,BCL2L2,MIR9-3HG,MYRF,BTRC,CALB2,THSD7A,CALM1,PTBP2,CAST,HIP1R,MAP7,LDB2,USP6,CD86,TMEM257,REPS2,CDC27,CDH2,CDO1,CHM,CHN2,NRXN3,NRXN1,TPP1,NMT2,HECTD1,CNGA3,COL4A5,SLC4A7,SMARCAL1,TOGARAM2,PNKD,ENTPD4,CRY2,ANKRD44,GDA,TENM4,CSNK1E,ATRNL1,PDE4DIP,APPL1,PHF14,GREB1,CFAP61,DOCK4,TOX,KIAA0513,CENPL,GIT2,DNAL1,ZEB2,MYEF2,TIAM2,COPS7A,GUCD1,PLPPR4,AK5,WDR20,FAM107B,KIF19,KBTBD11,DLG3,DLX1,GRIN3A,NYAP1,USP3,CPEB2,DPH1,ATN1,RCAN1,DTNA,MAMLD1,DYRK1A,DNM1L,HIPK3,SYT15,HEYL,SIDT2,RBM12,SUGP2,APH1A,MRO,KMT5B,RASA4,KCTD3,EIF5,ELAVL4,EML1,PAN3,EPB41,EPB41L2,COQ7,EPHA5,GPHN,ANKRD13B,SLC43A2,EPS8,CDHR1,DNAJC27,SIRPB1,ARMCX1,FAM198B,TAOK3,ATP8A1,FER,OLFM1,SPSB4,FGF13,AMOTL2,FHL1,SUCO,CAP2,FOXO3,EVL,NELFCD,CAMKK2,ATP6V1H,CELF1,ST6GALNAC3,ABLIM2,FYN,GABBR1,GABRA2,GABRB1,GABRB3,HBS1L,BRPF3,ZNF234,GAP43,ATP8A2,LRRC37A6P,KIAA1841,GATM,IGSF5,MMADHC,GLS,TNRC6A,PCDH11X,ZNF638,RAB40B,GNAO1,GNAS,FERMT2,GPR34,CNTRL,RAPGEF4,GRIK2,ADAMTS13,NR3C1,GRM2,PRDM5,GRM5,FAM107A,GUCY1A1,MUM1,PADI2,ZHX1,FRMD5,BACH2,SYNPO,SMAP1,LINC00667,C5orf24,ZIC5,RBPJ,METTL21A,KCNA6,KCNJ10,KCNN2,KIF5C,KLRC2,KLC1,LAMP2,STMN1,SFXN5,SYTL4,VWA5A,FGFBP3,ARHGAP12,NCOA7,CLEC18A,MARK1,LYPLAL1,MAT2A,MBNL1,CHIC1,KITLG,POC1B,MMP16,MN1,MOBP,CPNE9,SESN3,MSR1,N6AMT1,MYO7A,NCAM1,ZC3H12B,NDUFA5,NEK1,NEUROD1,NKX2-2,NOVA1,ODF2,PBX1,PCDH9,PDE1C,PIRT,ENPP2,GDAP1L1,SSH1,CCSER2,MAPKAP1,EXOSC10,PRRX1,MAGEL2,EPB41L4B,FAT3,CRLS1,PPP3CA,PPP3CB,CEP41,PKN2,MAPK7,MAPK10,GRAMD1C,HYDIN,PRODH,GDPD2,MTMR10,PTN,STK32A,PTPRB,FAM120C,PEX5,ZSCAN2,NKAIN1,RAB5B,RAD17,RALGDS,SH3TC2,ZNF493,RASGRF1,ARID4A,KHDRBS2,MSANTD2,RDX,REV3L,FIGN,RFX3,PRIMA1,SEC61A2,RIC8B,CCDC82,RERGL,CARF,GSTCD,CCDC25,BAALC,MCMBP,ATP8B4,ACER3,KCNIP3,TRAPPC13,FAM192A,AMER2,FOXRED2,SATB1,ATXN1,LRFN5,LRRTM4,SCN7A,ASIC4,SLC30A10,SUPT20H,TRA2B,SCAF8,ITSN1,PPP1R9A,SLITRK3,CNKSR2,SYBU,ST3GAL3,SEC31A,ST8SIA1,PPP4R3A,LIMS2,WDR47,SLC6A1,KANSL3,SLC6A9,SLC8A3,CCDC88A,SLC12A2,ZFP1,CDK5RAP2,MBD5,KIF13A,KDM4B,DOP1A,SON,ZCCHC24,CLUAP1,GLT8D1,PEG10,NFASC,ZNF621,ITPRID2,EPB41L3,LRRC4,NXT2,AJAP1,GSE1,KLHL7,NECAB1,FGD4,JMJD6,SYNE2,VPS13A,TAC1,TACC1,KAZN,DDHD2,AGTPBP1,ANO4,ACSL6,TCF4,DMXL2,KIAA0930,TCF12,AZIN2,ARHGEF12,CRTC1,AHCYL2,FAM200B,PMS2CL,SIRT1,CRB1,AKTIP,HEY1,TK2,HEY2,KCTD2,R3HDM1,TNS1,PIK3R5,PRMT8,TRIO,TRO,TRPC3,PPIL6,ANO5,TTC3,TUB,TMEFF2,SGK3,AMOT,SLAIN1,OSBP2,FLRT2,VAV2,TBC1D15,WIPF1,NSD2,PORCN,XPO1,ZBTB14,ZNF23,ZNF24,ZFP41,ZNF74,ZNF189,SH3GLB2,PLPPR5,ZFAND5,SMARCAD1,MEIS3,EMSY,PRDM10,LMAN2L,VPS35L,PCDH15,NAV2,SNX27,LINC00632,WIPF2,PDSS2,DOCK8,MARCH8,HNRNPA3,NUP214,CERS6,ACTR3B,ZNF248,VANGL2,SNX14,SSPN,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-30d-5p:TargetScan hsa-miR-30d-5p TargetScan 9.82E-166 5.52E-162 5.46E-164 5.03E-163 342 1144 "ABHD6,ACTN1,ARID1A,ELFN2,RNF157,BRAP,CDC7,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,AP1B1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,PPFIA2,EPB41L5,DGKZ,DGKD,CACHD1,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B1,ATP2B2,DPY19L3,BACH1,DCAF5,PROM1,KSR1,BMP7,FUBP1,BSN,CACNA1D,CALB2,CAMK2D,CARS,DGKI,EVI5L,LGI1,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,JAM2,KMT2C,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,ATRNL1,CHD5,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,FRMPD4,LONRF1,MATR3,KCTD8,MAML1,KIAA0087,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,CEP170,MAGI2,DDX46,SACS,G3BP2,RABGAP1L,DMD,CPEB2,DPYSL2,DRD1,DRP2,RCAN1,DTNA,ABCC9,EDNRA,EDNRB,EFNA3,RBM12,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,ELAVL2,ELAVL3,ELAVL4,RGS17,C3orf18,EML1,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,ATP8A1,MED12L,AMOTL2,MEX3B,FOXG1,IQCG,FOXO3,CAMKK2,CELF1,DACH2,NSG1,B3GAT1,MSANTD4,HHIPL1,NRG3,FYN,GABRA5,CHL1,GABRB1,ILDR2,JPH4,GALR1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,GLDC,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GPR26,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,NR3C1,GRM3,PRDM5,GRM5,KIF3A,RNF165,CELF3,MAN1B1,KLF12,MIER3,HLF,ELOVL5,NEGR1,CELF5,DOCK7,JAK1,KCNA4,CDH20,KCNJ3,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MDM4,MEIS2,MMP16,MOV10,JAKMIP3,ADAM22,MTTP,C10orf105,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NFIA,NFYA,NKX2-2,NOVA1,HCN1,OMG,OXTR,PDE3A,PDE4D,PIRT,PIK3CD,FAM216A,FTO,PRRX1,SDK2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CB,RASGEF1B,CEP41,EPDR1,MAPK8,ANKHD1,PXK,PTPN13,RALGDS,OXR1,RASGRF2,ARID4A,PRRT2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RNF220,PBRM1,RPRD1A,ALG9,RAVER2,CARF,RPS6KA2,SATB1,SBF1,ATXN1,DRAXIN,SCN2A,SCN3A,SCN8A,PRCD,HSPA4L,ITSN1,PPP1R9A,PPM1E,FRMPD1,KIF16B,CPEB3,NTNG1,MAGI3,CHD9,FNDC3A,CNKSR2,NLGN1,PAAF1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,RIMS1,FAM126B,KIF21B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,ACSBG1,NECAB1,MCF2L,CNTN2,ANO4,SATB2,PSD3,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,GZF1,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,RFTN2,CADM1,FAM155A,AMOT,PITPNB,MICAL1,PCDH20,MKRN3,REEP1,CA10,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,CERS6,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30c-5p:TargetScan hsa-miR-30c-5p TargetScan 9.82E-166 5.52E-162 5.46E-164 5.03E-163 342 1144 "ABHD6,ACTN1,ARID1A,ELFN2,RNF157,BRAP,CDC7,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,AP1B1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,PPFIA2,EPB41L5,DGKZ,DGKD,CACHD1,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B1,ATP2B2,DPY19L3,BACH1,DCAF5,PROM1,KSR1,BMP7,FUBP1,BSN,CACNA1D,CALB2,CAMK2D,CARS,DGKI,EVI5L,LGI1,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,JAM2,KMT2C,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,ATRNL1,CHD5,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,FRMPD4,LONRF1,MATR3,KCTD8,MAML1,KIAA0087,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,CEP170,MAGI2,DDX46,SACS,G3BP2,RABGAP1L,DMD,CPEB2,DPYSL2,DRD1,DRP2,RCAN1,DTNA,ABCC9,EDNRA,EDNRB,EFNA3,RBM12,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,ELAVL2,ELAVL3,ELAVL4,RGS17,C3orf18,EML1,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,ATP8A1,MED12L,AMOTL2,MEX3B,FOXG1,IQCG,FOXO3,CAMKK2,CELF1,DACH2,NSG1,B3GAT1,MSANTD4,HHIPL1,NRG3,FYN,GABRA5,CHL1,GABRB1,ILDR2,JPH4,GALR1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,GLDC,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GPR26,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,NR3C1,GRM3,PRDM5,GRM5,KIF3A,RNF165,CELF3,MAN1B1,KLF12,MIER3,HLF,ELOVL5,NEGR1,CELF5,DOCK7,JAK1,KCNA4,CDH20,KCNJ3,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MDM4,MEIS2,MMP16,MOV10,JAKMIP3,ADAM22,MTTP,C10orf105,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NFIA,NFYA,NKX2-2,NOVA1,HCN1,OMG,OXTR,PDE3A,PDE4D,PIRT,PIK3CD,FAM216A,FTO,PRRX1,SDK2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CB,RASGEF1B,CEP41,EPDR1,MAPK8,ANKHD1,PXK,PTPN13,RALGDS,OXR1,RASGRF2,ARID4A,PRRT2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RNF220,PBRM1,RPRD1A,ALG9,RAVER2,CARF,RPS6KA2,SATB1,SBF1,ATXN1,DRAXIN,SCN2A,SCN3A,SCN8A,PRCD,HSPA4L,ITSN1,PPP1R9A,PPM1E,FRMPD1,KIF16B,CPEB3,NTNG1,MAGI3,CHD9,FNDC3A,CNKSR2,NLGN1,PAAF1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,RIMS1,FAM126B,KIF21B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,ACSBG1,NECAB1,MCF2L,CNTN2,ANO4,SATB2,PSD3,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,GZF1,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,RFTN2,CADM1,FAM155A,AMOT,PITPNB,MICAL1,PCDH20,MKRN3,REEP1,CA10,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,CERS6,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30a-5p:TargetScan hsa-miR-30a-5p TargetScan 9.82E-166 5.52E-162 5.46E-164 5.03E-163 342 1144 "ABHD6,ACTN1,ARID1A,ELFN2,RNF157,BRAP,CDC7,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,AP1B1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,PPFIA2,EPB41L5,DGKZ,DGKD,CACHD1,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B1,ATP2B2,DPY19L3,BACH1,DCAF5,PROM1,KSR1,BMP7,FUBP1,BSN,CACNA1D,CALB2,CAMK2D,CARS,DGKI,EVI5L,LGI1,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,JAM2,KMT2C,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,ATRNL1,CHD5,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,FRMPD4,LONRF1,MATR3,KCTD8,MAML1,KIAA0087,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,CEP170,MAGI2,DDX46,SACS,G3BP2,RABGAP1L,DMD,CPEB2,DPYSL2,DRD1,DRP2,RCAN1,DTNA,ABCC9,EDNRA,EDNRB,EFNA3,RBM12,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,ELAVL2,ELAVL3,ELAVL4,RGS17,C3orf18,EML1,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,ATP8A1,MED12L,AMOTL2,MEX3B,FOXG1,IQCG,FOXO3,CAMKK2,CELF1,DACH2,NSG1,B3GAT1,MSANTD4,HHIPL1,NRG3,FYN,GABRA5,CHL1,GABRB1,ILDR2,JPH4,GALR1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,GLDC,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GPR26,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,NR3C1,GRM3,PRDM5,GRM5,KIF3A,RNF165,CELF3,MAN1B1,KLF12,MIER3,HLF,ELOVL5,NEGR1,CELF5,DOCK7,JAK1,KCNA4,CDH20,KCNJ3,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MDM4,MEIS2,MMP16,MOV10,JAKMIP3,ADAM22,MTTP,C10orf105,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NFIA,NFYA,NKX2-2,NOVA1,HCN1,OMG,OXTR,PDE3A,PDE4D,PIRT,PIK3CD,FAM216A,FTO,PRRX1,SDK2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CB,RASGEF1B,CEP41,EPDR1,MAPK8,ANKHD1,PXK,PTPN13,RALGDS,OXR1,RASGRF2,ARID4A,PRRT2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RNF220,PBRM1,RPRD1A,ALG9,RAVER2,CARF,RPS6KA2,SATB1,SBF1,ATXN1,DRAXIN,SCN2A,SCN3A,SCN8A,PRCD,HSPA4L,ITSN1,PPP1R9A,PPM1E,FRMPD1,KIF16B,CPEB3,NTNG1,MAGI3,CHD9,FNDC3A,CNKSR2,NLGN1,PAAF1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,RIMS1,FAM126B,KIF21B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,ACSBG1,NECAB1,MCF2L,CNTN2,ANO4,SATB2,PSD3,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,GZF1,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,RFTN2,CADM1,FAM155A,AMOT,PITPNB,MICAL1,PCDH20,MKRN3,REEP1,CA10,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,CERS6,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30b-5p:TargetScan hsa-miR-30b-5p TargetScan 9.82E-166 5.52E-162 5.46E-164 5.03E-163 342 1144 "ABHD6,ACTN1,ARID1A,ELFN2,RNF157,BRAP,CDC7,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,AP1B1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,PPFIA2,EPB41L5,DGKZ,DGKD,CACHD1,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B1,ATP2B2,DPY19L3,BACH1,DCAF5,PROM1,KSR1,BMP7,FUBP1,BSN,CACNA1D,CALB2,CAMK2D,CARS,DGKI,EVI5L,LGI1,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,JAM2,KMT2C,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,ATRNL1,CHD5,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,FRMPD4,LONRF1,MATR3,KCTD8,MAML1,KIAA0087,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,CEP170,MAGI2,DDX46,SACS,G3BP2,RABGAP1L,DMD,CPEB2,DPYSL2,DRD1,DRP2,RCAN1,DTNA,ABCC9,EDNRA,EDNRB,EFNA3,RBM12,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,ELAVL2,ELAVL3,ELAVL4,RGS17,C3orf18,EML1,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,ATP8A1,MED12L,AMOTL2,MEX3B,FOXG1,IQCG,FOXO3,CAMKK2,CELF1,DACH2,NSG1,B3GAT1,MSANTD4,HHIPL1,NRG3,FYN,GABRA5,CHL1,GABRB1,ILDR2,JPH4,GALR1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,GLDC,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GPR26,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,NR3C1,GRM3,PRDM5,GRM5,KIF3A,RNF165,CELF3,MAN1B1,KLF12,MIER3,HLF,ELOVL5,NEGR1,CELF5,DOCK7,JAK1,KCNA4,CDH20,KCNJ3,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MDM4,MEIS2,MMP16,MOV10,JAKMIP3,ADAM22,MTTP,C10orf105,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NFIA,NFYA,NKX2-2,NOVA1,HCN1,OMG,OXTR,PDE3A,PDE4D,PIRT,PIK3CD,FAM216A,FTO,PRRX1,SDK2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CB,RASGEF1B,CEP41,EPDR1,MAPK8,ANKHD1,PXK,PTPN13,RALGDS,OXR1,RASGRF2,ARID4A,PRRT2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RNF220,PBRM1,RPRD1A,ALG9,RAVER2,CARF,RPS6KA2,SATB1,SBF1,ATXN1,DRAXIN,SCN2A,SCN3A,SCN8A,PRCD,HSPA4L,ITSN1,PPP1R9A,PPM1E,FRMPD1,KIF16B,CPEB3,NTNG1,MAGI3,CHD9,FNDC3A,CNKSR2,NLGN1,PAAF1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,RIMS1,FAM126B,KIF21B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,ACSBG1,NECAB1,MCF2L,CNTN2,ANO4,SATB2,PSD3,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,GZF1,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,RFTN2,CADM1,FAM155A,AMOT,PITPNB,MICAL1,PCDH20,MKRN3,REEP1,CA10,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,CERS6,FXR1,FRMD6,GAN" MicroRNA hsa-miR-30e-5p:TargetScan hsa-miR-30e-5p TargetScan 9.82E-166 5.52E-162 5.46E-164 5.03E-163 342 1144 "ABHD6,ACTN1,ARID1A,ELFN2,RNF157,BRAP,CDC7,KIAA1211,PTCHD1,ADRA1D,LRFN2,AP2A1,AP1B1,INTS2,PCDH19,KCTD16,HACE1,OSBPL8,ABCD2,MARCH4,PCDH10,DOC2A,PITPNM2,CDC42BPA,LRCH2,PPFIA2,EPB41L5,DGKZ,DGKD,CACHD1,CADPS,MARCH3,DNAH17,ATP2A2,ATP2B1,ATP2B2,DPY19L3,BACH1,DCAF5,PROM1,KSR1,BMP7,FUBP1,BSN,CACNA1D,CALB2,CAMK2D,CARS,DGKI,EVI5L,LGI1,DLGAP2,DLGAP1,CCPG1,CFL2,B4GALT6,JAM2,KMT2C,NRXN3,CLCN3,QKI,MAP4K4,ARHGEF6,COL9A3,ABI3BP,NRG2,CLOCK,CRMP1,GDA,ATRNL1,CHD5,PITPNM3,ERC2,PLCXD3,CTH,FAM131B,PYGO1,KIAA0408,HDAC9,FRMPD4,LONRF1,MATR3,KCTD8,MAML1,KIAA0087,PITPNC1,ELMSAN1,JAKMIP2,ELMO1,MFAP3L,CEP170,MAGI2,DDX46,SACS,G3BP2,RABGAP1L,DMD,CPEB2,DPYSL2,DRD1,DRP2,RCAN1,DTNA,ABCC9,EDNRA,EDNRB,EFNA3,RBM12,CELSR3,FAM13A,MBNL2,PLXNC1,ASB3,KCTD3,ELAVL2,ELAVL3,ELAVL4,RGS17,C3orf18,EML1,DCTN4,EPB41,LRRC17,NCALD,CEP85L,RASL12,EXTL2,ATP8A1,MED12L,AMOTL2,MEX3B,FOXG1,IQCG,FOXO3,CAMKK2,CELF1,DACH2,NSG1,B3GAT1,MSANTD4,HHIPL1,NRG3,FYN,GABRA5,CHL1,GABRB1,ILDR2,JPH4,GALR1,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,GLDC,DBF4,GLI2,GNAO1,GPT2,PRUNE2,GPR26,EML4,CECR2,RAPGEF4,GRB10,GRIA2,RFFL,NR3C1,GRM3,PRDM5,GRM5,KIF3A,RNF165,CELF3,MAN1B1,KLF12,MIER3,HLF,ELOVL5,NEGR1,CELF5,DOCK7,JAK1,KCNA4,CDH20,KCNJ3,KCNN3,CAMK2N2,LIFR,PAXBP1,MSANTD3-TMEFF1,MARK1,MARK3,MAT2A,MBNL1,ADAM11,CHIC1,MDM4,MEIS2,MMP16,MOV10,JAKMIP3,ADAM22,MTTP,C10orf105,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NFIA,NFYA,NKX2-2,NOVA1,HCN1,OMG,OXTR,PDE3A,PDE4D,PIRT,PIK3CD,FAM216A,FTO,PRRX1,SDK2,EPB41L4B,PPP2R5E,PPP3CA,PPP3CB,RASGEF1B,CEP41,EPDR1,MAPK8,ANKHD1,PXK,PTPN13,RALGDS,OXR1,RASGRF2,ARID4A,PRRT2,GTDC1,FIGN,RFX2,RFX3,SEC61A2,RNF220,PBRM1,RPRD1A,ALG9,RAVER2,CARF,RPS6KA2,SATB1,SBF1,ATXN1,DRAXIN,SCN2A,SCN3A,SCN8A,PRCD,HSPA4L,ITSN1,PPP1R9A,PPM1E,FRMPD1,KIF16B,CPEB3,NTNG1,MAGI3,CHD9,FNDC3A,CNKSR2,NLGN1,PAAF1,FAM81A,PEX26,EPN2,PKNOX2,BTBD7,CPEB4,EPC1,LIMCH1,RIMS1,FAM126B,KIF21B,BDP1,KDM3A,HECW1,ARHGAP26,LARP4,NKAIN2,RGL1,ACSBG1,NECAB1,MCF2L,CNTN2,ANO4,SATB2,PSD3,NSD1,PUM2,GPRIN3,AP4E1,GPR161,ARL10,GZF1,NACC2,ASXL3,FAM124A,RIMBP2,R3HDM1,PDSS1,RUNDC3B,DCBLD1,RFTN2,CADM1,FAM155A,AMOT,PITPNB,MICAL1,PCDH20,MKRN3,REEP1,CA10,MAP3K12,CADM2,EVI5,ADAMTS9,HPS4,NAV3,FAM13C,FZD3,MARCH8,HNRNPA3,PHTF2,CERS6,FXR1,FRMD6,GAN" MicroRNA hsa-miR-411*:mirSVR_lowEffct hsa-miR-411*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.22E-165 1.25E-161 1.22E-163 1.13E-162 450 2000 "ACADM,NDRG3,FMNL2,ADD1,ESYT2,DPY19L2P4,OSBPL1A,NR0B1,WDR35,OSBPL8,PLA2G6,LRRC7,PCDH10,BBOX1,UNC79,ZFAT,DPP10,C6orf89,APC,MAGEE2,UPRT,ALS2,VAT1L,LRRC4C,LGR5,AQP4,PPP4R4,RGS20,ASPA,N4BP2L1,ATP6V0A1,DOCK11,ADAM23,TTLL9,MIR9-3HG,DCAF5,KSR1,BMPR1B,DST,SCAPER,MTMR2,NIPA1,PTBP2,TRIM41,CANX,CAST,CH25H,ISPD,MAP7,CCNH,CDH10,LGI1,CLGN,CHM,MS4A7,CNOT8,JAM2,KMT2C,EPS15L1,NRXN3,TJP2,FAM19A5,QKI,MAP4K4,NIPBL,CNN3,IQCK,AKAP6,BTF3L4,SLC4A8,TBPL1,ZFP28,PREPL,C2CD2,CREM,HAPLN1,NCOR1,GDA,MROH8,TENM4,CSF2RA,OSBPL3,VCAN,SOCS5,VAC14-AS1,CNTNAP2,DZIP3,PLCXD3,PNPLA8,CFAP61,ST18,NOS1AP,KIAA0408,DOCK4,RIPOR2,ARHGAP24,TOX,LONRF1,MATR3,KIAA0586,KCTD8,DGKB,SCRN1,DBI,GIT2,ARMCX4,DNAJC6,ZEB2,ZBTB24,HEPH,MYEF2,TIAM2,MFAP3L,FBXL5,DDX46,PLPPR4,NTM,WDR20,DLG2,DOCK2,SLC12A6,ACOT8,ABI1,GNE,MAMLD1,DNM1L,GOLT1B,E2F6,EDIL3,ATL1,KLHL5,FRY,OPTN,PHF20L1,SUGP2,KCTD3,IRAK4,ELAVL2,PCOLCE2,EML1,VPS13B,EPB41L1,EPB41L2,LRRC17,EPHA5,RABEPK,ERBB4,CDKL3,VPS26C,DNAJC27,EXTL2,EYA1,CLVS1,ABCA8,ZNF461,FABP7,ACSL4,GORAB,SLC9B2,FGF12,FGFR1,FGFR3,MEX3B,HPCAL4,CAP2,ANKFY1,SORBS1,UFM1,TPK1,ZNF605,ST6GALNAC3,STAU2,SDCBP2,STAG2,MEGF10,GAB1,GABRA1,C15orf41,DISC1,SEPT9,LRRC37A6P,KIAA1841,DNER,IGSF5,FAXC,GCNT2,TUBGCP4,SULT1C4,MSTN,ADAM28,MMADHC,LYVE1,GJB1,GK,TCERG1,GLRB,MSL3,MAP7D2,GPT2,WDFY3-AS2,GPM6B,FUT10,LILRA1,GPR19,NUDT21,PCLO,GRIA2,ADAMTS13,NR3C1,GRM8,BTN2A1,KIF3A,GSTM5,MAEL,ELOVL5,ZDHHC15,OPALIN,HSF2,HSP90AA1,ZNF546,C5orf24,ZIC5,LRRCC1,IL12A,DIPK1A,INPP5B,ITPKB,JAK2,SLC35G1,OLFM3,KCNA4,KCNC2,KCND2,KCNJ3,KCNMA1,KCNN3,KIF5A,KIT,STXBP5,KTN1,LAMP2,LIG4,MAP2,MARK1,AQP11,MATN3,MBP,KITLG,MMP16,JAKMIP3,MTR,NEXMIF,NAP1L1,NAP1L2,NDUFA5,NF1,NFE2L2,NOVA1,LRIT2,NTRK2,DDR2,NUCB2,CHAMP1,OPCML,P2RX7,PALM,PC,PCDH8,PCMT1,PCSK2,PDE3B,PDE4D,PDGFRA,GPR85,ZNF655,XRN1,FAM216A,PLCL1,PURG,MAPKAP1,ING3,POLR2F,POU3F2,MED1,PPM1B,RANBP3L,VSTM2L,PRKACB,GRAMD1C,DIRAS2,PROX1,VPS13C,SLC22A23,PTCH1,ANKHD1,UHRF1BP1,PTHLH,ELOVL2,PTN,STK32A,PTPRG,PEX5,ZNF615,RAD17,RAP1GAP,ZNF493,ARID4A,RBBP6,VEPH1,MSANTD2,RET,ERI2,MORC4,RGR,UBR7,RGS4,SLC25A36,RPRD1A,DCUN1D2,ROBO1,PCMTD2,CCDC102B,RPE,NEK11,UEVLD,FBXW7,BAALC,ZC3H14,MCMBP,STK32B,PTGR2,ZNF331,ATXN1,LRFN5,SCN2A,SCN8A,IL17RB,PEAR1,SFPQ,SCG5,KIF16B,CPEB3,NTNG1,CHD9,FNDC3A,FHOD3,CTXN2,SEC31A,DZIP1,WDR37,SLA,SLC1A3,PPP4R3A,BTBD3,KANSL3,CCDC88A,SLIT1,GKAP1,IFT122,ANKRD36,LIMCH1,SNAP25,MBD5,PDZRN3,MYO16,DOP1A,MYT1L,BDP1,FNBP1,GLT8D1,UHRF1BP1L,ERC1,ZNF423,ZC3H13,KIF1B,SRPK2,ZNF621,ZNF302,EPB41L3,CEP68,KANK1,AJAP1,FGD4,JMJD6,ADAMTS17,SYT4,C12orf76,KAZN,PJA1,DNMBP,EHBP1,SATB2,ZFP90,TRIM2,TCF12,WASHC4,CLASP1,AZIN2,PSD3,PUM2,ARHGAP9,CRTC1,DICER1,ITGB3BP,AP4E1,MTMR14,TLR4,LRRC8A,C5orf64,KAT6B,SYNPO2,STXBP4,TRPC3,TRPS1,PPIL6,ANO5,SSBP2,TTTY15,TUB,TMEFF2,TUBB1,FAM155A,USP1,VAV1,CCDC14,WIPF1,CLDND1,XPO1,XRCC4,ZIC3,MKRN3,SMARCAD1,SLC30A4,EMSY,EVI5,STMN4,LMAN2L,VPS35L,MDH1B,PCDH15,MPPE1,RGS7BP,SMIM8,HNRNPA3,FBXO36,KLHDC1,FRMD6,SLC4A10,CPNE4,SENP7" MicroRNA hsa-miR-519c-3p:mirSVR_lowEffct hsa-miR-519c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.39E-165 1.90E-161 1.85E-163 1.70E-162 424 1781 "NBAT1,SYS1,ACTN2,SLC25A25,CSMD3,GALNT16,CCDC85A,ADD1,SORCS1,USP31,RNF150,PTCHD1,ADRA1B,BEND6,NLGN4X,HECW2,WDR35,OSBPL8,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,GPAM,DGKD,TNRC6C,LGR5,MIER1,CDK10,ARHGAP5,PLA2G4C,MARCH3,NCOA1,NUMB,DDX3Y,INSYN2B,DPY19L3,TTLL9,ADGRB3,RGS11,BCL2L2,BCL7A,FUBP1,MTMR2,SGCE,NIPA1,OSGIN2,CACNA1E,CACNB2,KALRN,NGB,CAMK2D,CAMK2G,SYT6,CBR1,SHISA7,CBFA2T2,C1orf52,REPS2,CDC27,LGI1,NOG,CASC2,MS4A7,SYNPR,B4GALT6,KMT2C,EPS15L1,CLCN4,CLTC,QKI,CNR1,IQCK,AKAP5,SLC4A7,IFFO1,ZFP28,CNRIP1,MFSD4A,CHD1L,PNKD,CREB5,AKAP12,HAPLN1,TRIM69,FEZ2,ATRNL1,PDE4DIP,CNTNAP2,FAM169A,APPL1,ST18,DCAF4,USP6NL,NOS1AP,GAPVD1,FRMPD4,ZNF337,DGKB,DGKG,DNAL1,SPATA2,ZNF804A,C8orf34,ZEB2,MFAP3L,HP1BP3,CEP170,MAGI2,ZC3H11A,GUCD1,RHOBTB1,SNAP91,SRGAP3,G3BP2,DLG2,HS3ST4,HS3ST2,SLC25A18,DRD1,ACOT8,ABI1,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,ELAVL2,BSCL2,PAN3,EMX2,EPB41,EPB41L1,ANKRD13B,EPS8,ERBB4,MRPL37,TLR7,KATNAL1,WAC,ST3GAL6,MED12L,CAMSAP1,POLK,SEC23B,PCYOX1,ATP13A4,ANKFY1,SGIP1,NOP56,NELFCD,TACC2,NPTN,CELF1,GABRB1,GAD1,HBS1L,ZMYND11,ZNF274,GAP43,GART,DNER,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,DBF4,TNRC6A,MSL3,CBX1,INSM2,GPT2,ADGRA3,GPM6A,DIPK1C,GPR34,NUDT21,GPR37,PCLO,RAPGEF1,GRIA1,NR3C1,ZNF496,BTN2A1,MFSD2A,SOX21,GUCY1A1,WIF1,IRAK3,GPR45,PTGDR2,SHISA6,CELF5,SMAP1,IGF1,IL11RA,SLC35G1,KCNA1,KCNA6,KCNC2,KIT,LAMP2,CAMK2N2,SFXN5,C2orf80,ZNF667-AS1,MAP2,MAP6,MAPT,LDLRAD3,SCAMP5,AFF1,PTOV1,NRBP2,TAGLN3,MTR,MXI1,LYRM9,MYH6,MYO5A,MYO9A,NAP1L1,NAP1L2,NBL1,NCAM1,NCF2,NDUFA5,SFR1,NFIA,NFIX,NHLH1,NPTX2,NUCB2,OPRL1,KCNK10,PAX6,PBX1,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,PFKP,CDK14,DUSP26,SSH1,XRN1,GPSM2,SLC25A23,LRP12,PRRX1,SDK2,ING3,MED1,MINDY2,CCDC144B,PRKCZ,MAPK3,MAPK4,SLC22A23,DEF8,MDGA2,PLPPR1,UHRF1BP1,MTMR10,OCIAD1,PTPRD,PTPRE,FAM184A,OXR1,RASGRF1,RBBP8,RADX,BSDC1,REV3L,GTDC1,PRIMA1,TTLL7,RPRD1A,LGI2,ROBO2,ELP2,TMEM100,NEK11,FBXW7,ZC3H14,GLDN,RPS20,KCNIP3,CLIP1,ZNF331,FAM182A,AMER2,SATB1,ATXN1,SCN2B,SCN8A,TNFRSF19,PEAR1,TRIM46,PUF60,PPM1E,DOCK10,MAGI3,FBXO11,NUBPL,CLSTN1,WDR37,BTBD3,SMTN,WDR47,SLC6A8,KDM4D,SLC8A1,RAB3GAP1,ARHGEF40,SLC11A1,SHANK2,SLC12A2,NAPB,SLC15A2,TET1,CPEB4,ZNF667,SORCS3,TTC17,RIMS1,SNAP25,SNCA,MBD5,USP33,PDZD2,TNIK,KIF21B,SP4,UHRF1BP1L,KDM4C,IDI2-AS1,CDK19,ZBTB43,TSPYL2,RBM26,NFASC,SRPK2,EPB41L3,SEPT8,DIP2A,STAC2,AJAP1,NSFL1C,MLC1,SYN2,ATP11A,TACC1,MTCL1,EXOC7,UNC5D,TMEM136,ATMIN,TCF4,CUX2,ZEB1,AZIN2,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,CRB1,ITGB3BP,AP4E1,TIAM1,ZFP91,TMPO,RIMBP2,RGMB,SMUG1,TRPS1,TUB,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,WIPF1,CLDND1,KCNT2,LYPD6,ZBTB38,SYNC,EMSY,PRDM2,SLC38A1,EVI5,STOX2,PRDM8,PCDH15,NAV2,SLC17A7,C12orf4,GOPC,FAM13C,FZD3,UBE3B,PAK5,FBXO36,FAM219B,NLRP3,TTC7A,SLC39A12,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-miR-579:mirSVR_highEffct hsa-miR-579:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.80E-165 2.70E-161 2.59E-163 2.39E-162 437 1892 "RALGAPA1,CLK4,NCKAP5,SYS1,ACTN2,CSMD3,NDRG3,ADARB2,DSCAML1,ADD3,BRAP,SLC12A5,ERMN,PWWP2A,INTS2,KCTD16,KIAA1324,ALCAM,BCAR3,ABCD2,BBOX1,GPRASP2,ZFAT,OGT,DPP10,PHF12,PPFIA1,PKP4,ANXA7,APAF1,APC,UPRT,GPAM,LRRC4C,BCAS1,SHTN1,IGDCC4,TMEFF1,ARHGAP5,CADPS,MARCH3,ZBTB10,NUMB,EIF4G3,ATP2A2,ALDH7A1,DPY19L3,ADAM23,ADGRB3,SEC11C,BID,PROM1,BMPR1B,DST,ARHGEF7,CA8,CALB1,CALM1,KALRN,CAMK2D,ISPD,LDB2,AIFM1,SCARB1,TMEM257,CD38,SEPT7,CDC42,CDH8,CDH10,ZMYM4,LRRFIP1,LGI1,MAGI1,CHM,CHN1,CHN2,CASC2,B4GALT6,NDST3,IGFBP7-AS1,QKI,MAP4K4,CNR1,CNTN1,AKAP7,COL4A5,SLC4A7,SLC4A8,AHCTF1,ACBD5,MYRIP,ZFP28,CLOCK,RBM39,ANKRD44,GDA,ARHGEF10,ATRNL1,NCAN,SOCS5,CTNND1,ST18,CCDC144A,HDAC9,KATNAL2,ARHGAP24,CENPL,KIF26A,LONRF1,LIN54,DCC,MYEF2,TIAM2,CEP170,BLOC1S6,ALKBH8,PLPPR4,SV2B,NTM,RABGAP1L,DLG2,DMD,DPP6,DRD1,ACOT8,DTNA,MAMLD1,DNM1L,ABCC9,GOLT1B,E2F5,KLHL5,YAF2,SH3GLB1,EGFR,AASS,EIF5,IRAK4,COPS4,TENM1,EPB41L2,ENPP6,GPHN,ETV1,F5,ARMCX1,ACSL4,PTK2B,DLC1,FCGR1A,STRADA,FER,FGF14,FGFR1,CAP2,SLC37A3,C2orf88,NBEA,SORBS1,UFM1,STAMBP,ATP6V1H,ATP2C1,ERGIC3,NSG1,STAG2,DKK3,GABRA2,ZNF44,HBS1L,ARPP21,IQGAP2,ERAP1,SIGLEC8,DISC1,IGSF5,SULT1C4,AHDC1,PCDH17,GGTA1P,PPARGC1A,MALT1,GK,GLRB,GNAS,WDFY3-AS2,GPM6B,B4GALNT4,GPR22,GPR34,GRIA4,GRM5,ZNF496,KIF3A,BVES,MAP4K5,TMEM179,RASSF8,HAS2,NCKAP1L,DDX19B,INSYN1,BACH2,SYNPO,HNF4G,HNMT,IGFBPL1,USP51,OPALIN,HSF2,SMAP1,IRF8,ZNF546,RBPJ,LRRCC1,IGSF1,SCIN,IL6ST,ZNF678,TUBB2B,LRRTM3,SLC35G1,KCNA4,KCNC2,KCNH1,KCNN2,KLRC3,LIMS1,VWA5A,HECTD2,NCOA7,SMAD1,MAPT,MARK1,SYT9,IL17D,MDM4,LRP1B,MEST,KCTD6,POC1B,MITF,MOBP,BLOC1S2,MSR1,CTNNA3,MTTP,MXI1,MYO6,MYO9A,HNRNPM,NAP1L3,NCAM1,IDNK,OTOGL,NOVA1,NRCAM,SMIM11A,HCN1,NUCB2,GPR88,OMG,ZNF713,GPR137C,PAK3,CNTN3,PCSK5,PDE4D,PDGFRA,FAM98B,CDK14,SSH1,PIK3R1,ZNF655,A2ML1,PLP1,PCDH18,PURG,MAPKAP1,STRN3,PSAT1,MAGEL2,EPB41L4B,TNPO2,SH3KBP1,POU3F2,PPM1B,PPP2R5E,PRKACB,PRKCB,PKN2,MAPK9,HYDIN,RELN,CNNM2,GDPD2,MDGA2,CNTLN,BDNF-AS,MTMR10,PTHLH,PTPRB,PTPRD,TTC13,MARCH1,TMEM255A,CCDC40,FAT4,ENOX1,ARID4A,RADX,RDX,REV3L,PRRT2,FIGN,ZFHX4,CCDC82,ZNF532,CARF,GSTCD,ROBO1,NEK11,ATP8B4,GLDN,ACER3,LRRK2,FAM161B,SYNDIG1,WLS,RTN1,TRAPPC13,MIR124-2HG,SCN3A,LRRTM4,SCN8A,FNIP1,TRA2B,HSPA4L,NTNG1,FNDC3A,NLGN1,WDR37,SLC1A3,FAM81A,SLC20A2,SLCO1A2,SLC22A4,CPEB4,ZFP1,SMARCE1,RCOR3,ANKRD36,RIMS1,SNAP25,SNRPN,UNC80,KDM4B,DOP1A,TNIK,SOX5,ZCCHC24,MYCBP2,KDM4C,ZC3H13,NPAS3,TAB2,CLASP2,POGZ,NKAIN2,ERBIN,ELOVL4,NEK4,TTBK2,DIP2A,ADHFE1,FAM168A,NECAB1,FGD4,SUPT5H,VAMP1,VPS13A,PLCB1,SYPL1,SYT1,TAC1,CAMTA1,KIAA1107,ANO4,VWC2,DMXL2,CUX2,WDR7,RALYL,PCDHB3,AKNA,PMS2CL,SIRT1,THRA,BHLHB9,TMPO,NPL,C9orf85,SYNPO2,TRPS1,ANO5,GORASP1,P2RY12,KCNK12,XPO1,CFAP298,MICU3,ZNF45,ATP6V0E2,FMN2,SPHK2,TCEAL7,FSTL5,EML6,SPIRE1,CADM2,PRTFDC1,STOX2,PRDM10,HPS4,SLC17A6,RGS7BP,GOPC,FAM13C,UBE3B,SMIM8,HNRNPA3,PHTF2,SSPN,FRMD6,NETO2,NETO1" MicroRNA hsa-miR-892a:mirSVR_lowEffct hsa-miR-892a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.16E-165 4.02E-161 3.83E-163 3.53E-162 423 1776 "VWA5B2,SDE2,KCNH8,ASPHD1,ASIC2,AS3MT,GPRIN1,ADD3,PLEKHH1,SNX30,CASKIN1,KCTD16,HACE1,WDR35,CC2D2A,PLA2G6,SRPX,PCDH10,GPRASP2,MRTFA,AMPH,LRCH2,LCORL,MYH7B,PHF12,CACHD1,API5,USP37,SHROOM2,SEMA4G,MARCH3,DACT3,ATM,CCDC181,ZNF582,NOL4,DPY19L3,BBS2,BCL2L2,BID,SYNJ1,FUBP1,CASTOR3,MTMR2,SGCE,CACNB2,CACNB4,CABP7,CAST,PRC1,CCKBR,CCNH,CD86,ARHGEF1,REPS2,CDC27,LGI1,DLGAP1,FOXN3,SOCS6,CHN1,NDST3,KMT2C,NRXN3,KIAA1549L,CLCN4,CLTA,TJP2,C4orf33,MAP4K4,FHL5,CNR1,CNTFR,IQCK,AKAP6,WHRN,MAGED1,ABI3BP,RCHY1,ZFP28,PNKD,AKAP12,NCOR1,GDA,CSF1,TENM4,MICAL2,OSBPL3,NCAN,VAC14-AS1,CFAP61,NRSN1,KIAA0408,DOCK4,GAPVD1,DCAF8,TOX,DAPK1,DNAJC6,ZBTB24,TIAM2,PLPPR4,SPOCK3,NTM,RABGAP1L,SEC16A,RAB39B,DMD,CASP8AP2,ARRDC4,ECM2,DUSP9,EDN1,EDN3,ATL1,SEMA3D,RBM12,YAF2,IRAK4,TNK2,CERCAM,MRNIP,EML1,EPB41L2,RCAN2,EPHA5,ENPP6,SRRM1,TMEM74,RASL12,MRVI1,F5,ARMCX1,TMEM132C,PTK2B,TAOK3,CORO2B,ATP8A1,FCGR1A,TOMM40L,FGF12,BAIAP2,TMEM164,FHL1,POLK,ATP5PD,RGPD5,IQCG,EVL,FLT1,EFCAB2,JKAMP,PDLIM5,TPK1,NPTN,NSG1,PNMA2,AP4B1,ABLIM2,GABRB3,BRPF3,ZMYND11,ARPP21,GAP43,ZNF559,WASHC2A,ADAM28,PPARGC1A,MALT1,SPIN1,TOX3,LUZP2,DCLK2,GNAL,ZNF782,PRUNE2,GPM6B,LILRA2,EML4,PLCD4,GRID1,GRIK3,CACFD1,GRM5,BTN2A1,ZBTB49,LINC01551,SOX21,GUCY1B1,ATOH8,WIF1,MAEL,PADI2,DDX19B,MIER3,VSIG4,ZNF491,DHX35,HSD17B1,LRRC75A,RBPJ,USP54,LIX1,INPP5B,ITGA7,SLC35G1,KCNA2,KCND2,KCNJ16,LAMP2,LIMS1,VWA5A,ARHGAP12,C2orf80,NAT8L,MARK1,CHIC1,PPM1L,MN1,ERICH3,ADAM22,CTNNA3,MYO6,RTL5,NAP1L2,NCAM1,NEFM,NELL1,NOVA1,DNHD1,SLC11A2,OCRL,CHAMP1,OLR1,OXTR,P2RY1,ZDHHC22,PCDH9,PDE3B,PDE4D,PDYN,OLA1,CDK14,GDAP1L1,TMIE,ZFYVE21,FTO,MTRF1L,ING3,FAT3,PPP1R1A,CRLS1,KANSL1,PRKAB2,CEP41,PRKCG,PRKCZ,MAPK4,GDPD1,WBP1L,APTX,GON4L,SNRK,PIGG,CNTLN,PTHLH,SPDL1,PTN,TMEM260,STK32A,OCIAD1,PTPRD,PTPRO,FAM120C,NKAIN1,TUG1,TMEM231,PID1,RAD51D,ZNF793,ENOX1,ARID4A,HKR1,MSANTD2,SLC6A15,ZYG11B,ZMAT4,DPF2,RIT2,PBRM1,CCDC82,CARF,PCMTD2,MRAP2,NEK11,FBXW7,SPIN3,ACER3,LRRK2,STX1B,DGLUCY,MIR124-2HG,ATXN1,SCN2A,ELMOD1,TRA2B,KIF16B,ASAP3,FNDC3A,CCDC92,NLGN1,PPP4R3A,SLC6A1,LRRC55,SLC6A11,KDM4D,SLC8A1,ARHGEF40,SLC11A1,SLC12A2,BTBD7,ATF7IP,SLCO1A2,SLIT1,OGDHL,SORCS3,SMARCD3,SMARCE1,ANKRD36,SNAP25,MBD5,SNRPN,UNC80,DOP1A,SOX2,BDP1,SP2,ZSWIM8,CLUAP1,HECW1,MYCBP2,TSPYL2,RBM26,DDN,TAB2,STOX1,NEK4,CEP68,DIP2A,SEPT3,GSE1,FAM168A,FGD4,ZC3H4,SYT1,SYT4,TAC1,ATP11A,TACC1,TACR1,ANKRD12,SEMA4A,CAMTA1,TAF6,DNMBP,TMEM136,EHBP1,TRIM2,CLASP1,AZIN2,SLC19A3,SIRT1,ZFPM2,CRB1,ITGB3BP,AP4E1,ZMAT3,TGFBR3,HHIP,TMEM9,TK2,ASXL3,RIMBP2,KCTD2,C5orf64,RBFOX2,ZNF346,SYNPO2,TRIO,STXBP4,ZMYND8,TSC1,SSBP2,TTC3,CLHC1,TMEFF2,CADM1,AMOT,BCL2L13,VLDLR,TBC1D15,WIPF1,RICTOR,PCDH20,ZNF24,LYPD6,CELF4,ZNF154,POLR3H,EML6,SH3GLB2,SPIRE1,ZNF213,DHX33,WNK1,CADM2,SLC38A1,STOX2,SLC17A6,MVB12B,RGS7BP,PAK5,NLRP3" MicroRNA hsa-miR-599:mirSVR_lowEffct hsa-miR-599:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-164 8.71E-161 8.21E-163 7.56E-162 414 1705 "NBAT1,CSMD2,ARID1A,CSMD3,TMEM132B,GALNT13,ESYT2,PTCHD1,PCDH19,RTL9,OSBPL8,ZNF578,LRRC7,SPOP,CARNS1,BIN1,ANK1,LRCH2,ANK3,APBB2,DDO,PHYHD1,PPFIA3,MIER1,SEMA4G,PDXK,CDK13,MARCH3,STK33,ASPH,ZBTB10,ATM,SLC4A4,RNF182,N4BP2L1,DPY19L3,ADGRB3,ST3GAL5,DDR1,CABP7,THSD7A,KALRN,RUNX1T1,CCKBR,KRIT1,USP6,INA,CBFA2T2,SCARB1,C1orf52,ZBED1,CDC42,CDH2,SOCS6,PLEKHB1,JAM2,TAOK2,NDST3,KMT2C,CLCN4,FBXO7,ARMC8,BTF3L4,MYRIP,MFSD4A,CREM,AKAP12,RGS6,MICAL2,OSBPL3,ATRNL1,CNTNAP2,RASGEF1C,KIAA0040,RIMS2,USP6NL,CYBB,KIAA0408,FRMPD4,EARS2,ZNF337,RASSF2,LONRF1,KCTD8,DGKB,PABPC5,AIF1L,GIT2,DGCR5,ZEB2,KIAA0753,SPOCK3,NTM,MTX3,CHRDL1,DLG2,RAB39B,DMD,USP3,DNAH9,CPEB2,DRD1,TOM1,DNAJB6,E2F5,EDN3,EDNRA,EDNRB,HIPK3,FCF1,TMTC1,FSD1L,PHF20L1,MBNL2,KMT5B,ABI2,GOLGA7,SORBS3,ELAVL3,ELAVL4,RGS17,C3orf18,USPL1,VPS13B,ANKRD13B,EPS8,IGSF6,ZNF549,TMEM74,TLR7,RRAGB,KATNAL1,MRVI1,F8,CLVS1,ABCA8,CACNG2,ACSL4,PTK2B,DLC1,STRADA,SEC24B,FGF12,FGF14,FGFR1,PRKAG2,SUCO,UBE2E3,MEX3B,FOXO3,ANKFY1,C2orf88,SPECC1,APOPT1,FAM49B,CAMKK2,ATP2C1,NSG2,ST6GALNAC3,NSG1,AP4B1,PHYHIPL,MEGF10,HRASLS5,GABRA5,GABRB1,GABRG1,ZMYND11,NCKAP1,IQGAP2,MSTN,CYP46A1,AHDC1,MALT1,CRCP,SPIN1,GLUL,PCDH11X,CBX1,KDM2B,GNAO1,GNAS,GNG4,ADGRA3,GPM6B,LPAR4,GPR37,PCLO,GRIA1,DIDO1,PLCD4,GRID1,GRM5,ZNF496,LINC01089,LINC01551,AP4S1,WIF1,UBE2QL1,PADI2,MAN1B1,DDX19B,HLF,SYNPO,HTR5A,C5orf24,LRRTM1,KCND2,KCNJ3,KCNMA1,KIF2A,KLRC3,IPO5,VWA5A,HECTD2,MAP6,MARK1,MATN2,MBD1,LRP1B,MEIS2,SRSF12,KITLG,DBNL,ADAM22,NRBP2,N6AMT1,MTR,NDUFA5,NELL2,NEUROD1,NFIA,NFE2L2,NOVA1,PCBP3,OCRL,OPCML,OXTR,GLIPR1L2,PAK3,CNTN3,PAX6,DPY19L2P2,PRTG,PDGFRA,GNG2,OLA1,FAM218A,A2ML1,PLP1,ING3,SEPT4,NXPH1,PPP3CB,RASGEF1B,PRKCZ,SLC22A23,CNTLN,PLPPR1,MTMR10,ELOVL2,PTN,PTPRB,EML5,FAM120C,PEX5,ARID4A,ZDHHC14,ZMAT4,DPF2,REV3L,MORC4,FIGN,UBR7,RGS7,ARHGEF10L,ZFHX4,TMLHE,TMEM206,ELP2,CCDC102B,RPE65,SNX22,SPIN3,ATP8B4,RPL38,LGR4,ABCA11P,YJEFN3,CLIP1,SATB1,ATXN7,FNIP1,SOX6,STUM,SGK1,MYO18A,NTNG1,FHOD3,R3HDM2,SLITRK3,NUBPL,SLA,FAM81A,BTBD3,SMTN,SLC8A3,KBTBD4,SLC12A2,SLC15A2,BTBD7,ATF7IP,EPC1,GKAP1,SMARCA4,SMARCE1,SNAP25,MBD5,ZNF415,PDZRN3,WDTC1,ZCCHC24,BDP1,DOK5,SP2,SP4,NMNAT2,KDM4C,UNC5B,PEG10,KIF1B,TSPYL2,RBM26,C11orf87,TAB2,ATP10B,PBLD,TROVE2,CLSTN2,ITPRID2,STAU1,ELOVL4,NEK4,KANK1,SULF2,SEPT3,SUPT5H,COBL,SLC37A2,KAZN,MTCL1,MLST8,EXOC7,TAL1,CNTN2,ADGRL3,VWC2,RPGRIP1L,SYNE1,DOCK9,OBSL1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,CRB1,ITGB3BP,AKTIP,TK2,TLL2,TMPO,DAAM2,RIMBP2,RBFOX2,TPM3,ZNF346,PDSS1,ZMYND8,ANO5,RFTN2,FAM155A,UGT8,FLRT2,PLEKHH2,ZNF709,BCL2L13,VAV2,KCNK12,XRCC4,ZIC3,MICU3,KCNT2,GPR158-AS1,SLC26A10,LYPD6,FSTL5,WNK1,EMSY,SLC38A1,PCDH15,NAV3,SNX27,PARP11,HNRNPA3,FBXO36,CERS6,SNX14,NETO1,SOCS4" MicroRNA hsa-miR-424:mirSVR_highEffct hsa-miR-424:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.17E-164 1.22E-160 1.14E-162 1.05E-161 387 1490 "ABCF1,KCNH8,NCKAP5,SYS1,CSMD2,CCDC85A,GALNT13,ADD2,AXIN2,KIAA1211,ADRB2,KIDINS220,AP2A1,AP2A2,DISP3,LRRC7,ALAD,SRPX,ARHGAP20,ALK,OGT,ANK2,CNTNAP1,GPAM,ALS2,BCAS1,PPFIA3,APP,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,NCOA1,DDX3Y,SLC4A4,TTLL9,MPDZ,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,BTRC,CA8,CACNA1B,KALRN,PTBP2,VXN,VSTM2A,CAST,SPAG9,MAP7,RUNX1T1,ARHGEF1,CDC27,CDC42,PPT2,CLCN3,CLCN4,NRXN1,COG1,CLU,TPP1,QKI,SLC4A7,SLC4A8,TBPL1,ACBD5,MYRIP,MFSD4A,SLC35F1,SEC31B,CLOCK,PREPL,AKAP12,CRYM,LRIG1,FEZ2,FEZ1,MICAL2,SOCS5,ERC2,CFAP61,DCAF4,USP6NL,CX3CR1,CYBB,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,DCAF8,PHF19,KCTD8,ARMCX2,YTHDC1,JAKMIP2,C8orf34,PLEKHM1,MYEF2,FBXO25,SPOCK3,NTM,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SIDT2,RBM12,PHF20L1,MBNL2,ABI2,PLEKHA1,PAN3,EN2,RCAN2,DENND4A,CEP85L,SPEG,CDHR1,RTN3,EYA1,NRN1,ACSL4,FGFR1,FHL1,SUCO,MEX3B,RGPD5,SLC37A3,UFM1,PDLIM5,ZNF605,CELF1,CSPG5,NSG1,FYB1,CHL1,BRPF3,ARPP21,DISC1,DNER,SESN1,USP19,PCDH17,GHR,GLS,INSM2,GNAS,FERMT2,GPD2,PCLO,GRIA2,GRM7,ZNF496,RNF165,WIF1,RASSF8,ZHX1,FRMD3,HMGB1,OPALIN,HSF2,HTR2A,MSL1,RBPJ,NIM1K,DOCK7,INPP1,NME9,SLC35G1,KCNC2,KCND2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,ARHGAP12,MAP4,LYPLAL1,MARK3,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,THYN1,MYBPC1,RTL5,PABPC1L2A,NDP,NELL1,NOVA1,SLC11A2,NTRK3,ODF2,OMG,GPR137C,CNTN3,ETFRF1,PCDH9,PCMT1,PDE3A,PDPK1,SLC10A4,BEST3,PIK3R1,JAKMIP1,PLP1,PSAT1,PRRX1,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,GDPD1,MASP1,RELN,CNNM2,SYTL2,GDPD2,SNRK,CNTLN,PTHLH,STK32A,ZSCAN32,PTPRD,PEX5,PID1,TMEM255A,FAT4,RBBP6,HKR1,KHDRBS2,ZDHHC14,RET,RFX4,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,RPL15,ARMH4,FBXW7,SYNDIG1,ABCA11P,KCNIP2,KCNIP1,ZNF568,TMEM156,SALL1,MAPK12,SEMA6D,SATB1,ATXN2,SCN2A,SCN3A,LRRTM4,SCN8A,TNFRSF19,ASIC4,ELMOD1,SLC30A10,SELL,COPZ1,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,SHC4,HKDC1,FHOD3,NLGN1,ST3GAL3,ANKRD6,ZNF365,FAM81A,RAB3GAP1,ARHGEF40,CCDC88A,KBTBD4,SLC20A2,SLC22A4,CPEB4,SLN,RCOR3,SNAP25,MBD5,UNC80,SON,MYT1L,CLUAP1,UNC5B,ZC3H13,KIF1B,TSPYL2,NPAS3,NFASC,TAB2,NKAIN2,ACSBG1,PRRC2C,SYNE2,C3orf70,SYPL1,SYT4,C12orf76,KAZN,PJA1,UNC5D,WWC1,TBCEL,TCEA1,SATB2,TPCN2,TRIM2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,CRB1,TGFBR3,ERCC6L2,HEY2,TMOD1,TPM2,RUNDC3B,TRPC1,CADM1,AMOT,LGI4,ZNF28,TRIM9,FSTL5,EML6,ANKS1B,SLC30A4,PMEPA1,PRDM2,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,FBXO36,ADAMTSL3,FXR1" MicroRNA hsa-let-7b:mirSVR_lowEffct hsa-let-7b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.45E-164 1.94E-160 1.79E-162 1.65E-161 442 1944 "AS3MT,GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,CDC42BPA,ANK1,ANK3,LCORL,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM23,ADAM15,SNAI3-AS1,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,NFS1,USP6,SLC16A4,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,CACNA2D2,ASIC3,MS4A7,CNOT8,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,CLIP3,TRIM69,ABCG1,CS,RGS6,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,CMTM5,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,DCT,ZBTB24,MYEF2,MFAP3L,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,ARNT2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,ACOT8,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,ABCC9,SNX29,EDNRB,ANKRD46,YAF2,EFNB3,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,VPS13B,EPB41L2,COQ7,DMTN,EPHB1,ANKRD13B,RABEPK,NCALD,CDHR1,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,TOMM40L,FGF1,HPCAL4,CAP2,IP6K2,FLT1,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,IP6K3,SIGLEC8,DISC1,ATP8A2,KIAA1841,GHR,PPARGC1A,LYVE1,RUNDC3A,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,LINGO1,ATOH8,MAEL,HAS2,LINC01102,HLF,HMGCL,ZDHHC15,OPALIN,LRRC75A,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,KCND1,KCNJ10,KIF5C,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,MYO9A,PABPC1L2A,ZC3H12B,NDUFA5,SFR1,NEFM,NELL1,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,OXTR,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PLCB2,PLP1,HMGCLL1,PURG,TRHDE,MAPKAP1,SCHIP1,RANBP3L,PRKACB,RAB39A,PKN2,MAPK4,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,TMEM260,PTPRD,PTPRG,FAM120C,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,TRIM68,KCTD17,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,UEVLD,SPIN3,KIAA0895L,TCP11L1,PTGR2,MEG3,RTKN,TRAPPC13,ATXN2,SCN4B,PRCD,ASIC4,SEC14L1,TRIM46,CASC3,FOXRED1,HSPA4L,ITSN1,CPEB3,ST6GAL1,ANKRD6,WDR37,SLC1A7,BTBD3,EPN2,FAM214B,SLC6A1,SLC6A8,SLC8A2,ATF7IP,CPEB4,MAST1,SMARCD3,MYH15,IFT122,INAVA,FAM126B,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,NFASC,TAB2,POGZ,ITPRID2,SSTR2,ST5,SYT11,MLC1,FNDC9,PLCB1,TAC1,FAM208A,PDLIM2,VWA3A,TRIM2,RPGRIP1L,WDR7,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,DICER1-AS1,AP4E1,ARL10,TIMP4,ERCC6L2,DAAM2,KCTD2,TNFRSF1B,C5orf64,PIK3R5,NPL,C9orf85,WBP2,CHST5,SMUG1,ELP5,TRIO,STXBP4,TRPC3,NTSR2,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,MICU3,ZNF28,ZBTB38,ZBTB16,MEIS3,ZNF225,WNK1,CSDE1,FIP1L1,TRIM16L,CASC15,NUP214,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-1254:mirSVR_lowEffct hsa-miR-1254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.82E-164 2.14E-160 1.97E-162 1.81E-161 446 1979 "CPNE2,SERPINA3,DGCR6,SYN3,ACADM,NBAT1,SYS1,GPRIN1,KLHL32,RNF157,ADD1,SLC12A5,ERMN,KIAA1211,DPY19L2P4,SNX32,PCDH19,RTL9,PLA2G6,ZNF578,C1QTNF1,ALAD,PCDH10,LTBP4,FAM135A,ZNF687,KIF6,OGT,ANK1,PI16,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB1,EPB41L5,APLP1,DGKD,ALS2,NT5C3B,PPFIA3,LGR5,SHROOM2,SEMA4G,MADD,CASK,MARK4,PCDHGB4,NUMB,RASL11B,ASTN1,CADM3,N4BP2L1,NOL4,ATP6V1G2,LINC00847,BCL2L2,DNAJC27-AS1,DCAF5,LINC00906,CACNA1G,MYRF,BAIAP3,MMD2,CA4,CACNA1E,DDR1,CACNB2,CALB1,HAP1,CAPN3,RUNX1T1,KYAT1,CCNH,P2RX6,CD38,LRRFIP1,LGI1,DLGAP1,CCPG1,SRSF11,CHGA,CHI3L2,CHM,CHN2,CHRM1,CHRNA4,B4GALT6,ARHGAP22,NRXN3,PLAA,STOML1,FBXO7,ARMC8,AKAP6,SLC4A8,COX4I1,SMARCAL1,MYRIP,ZFP28,SLC35F1,CPS1,PNKD,CDC42BPB,SLC32A1,CRYBB1,ABCG1,SNCAIP,MICAL2,OSBPL3,CSNK1G3,VAC14-AS1,KIAA0040,CMTM5,CFAP61,CTNND1,RIMS2,FAM131B,NOS1AP,GAPVD1,SNPH,FRMPD4,KIF26A,IST1,DAPK3,SIRPA,DCC,KIAA0753,TMCC2,DLG2,DLX1,DMD,DNM1,DNM2,GOLT1B,WDPCP,PHC2,SIDT2,YAF2,EGFR,TMEM35A,MFSD10,EPB41L1,TMEM74,ANKMY1,RASL12,EXTL1,SIRPB1,MRVI1,PTK2B,ZIC4,ATP8A1,CHST15,FDFT1,PRMT5,PPP1R1B,MED12L,SCARA3,HPCAL4,FOXG1,RGPD5,FOXM1,EVL,NOP56,ZCCHC17,POMT1,CAMKK2,SDCBP2,MEGF10,GABRA3,ZNF44,HBS1L,AHCYL1,BRPF3,B4GALNT1,JPH4,ZNF274,NEK6,MTHFD2,DISC1,SEPT9,WASF3,KIAA1841,NEU3,CYP46A1,AHDC1,GFAP,GGT5,CRCP,MSL3,STARD3,ZNF638,GPT2,TDRKH,GPR12,STON1,NUDT21,GRID1,ADAMTS8,GRM1,GRM2,GRM7,ZNF496,BTN2A1,LINC00839,RNF165,TMEM25,AP4S1,RNFT2,PADI2,HRH3,BACH2,VSIG4,LRRC75A,SHISA6,CELF5,ICA1,RBPJ,KIAA1755,LIX1,SLC6A17,ITGAM,KCNJ10,GATD1,KIT,A1BG-AS1,PAXBP1,LMO2,SYTL4,NCOA7,LSS,MAN2A2,ZFYVE27,MDFI,CHIC1,SCAMP5,XRRA1,MOBP,MSI1,JAKMIP3,BLOC1S2,ADAM22,PTOV1,RSPO2,LYRM9,MYO7A,FXYD7,P2RY13,NCAM1,NCF2,SLCO1C1,NFYA,NINJ2,NME4,PCBP3,NUCB2,OCRL,OGDH,OPHN1,LOC100128398,ZDHHC22,SNTG1,PCDHGC3,PCSK5,PDE4D,PIRT,GNG2,PFKFB3,PFKP,NOMO2,CCSER2,XRN1,PKM,SMOX,PLP1,SLC25A23,LRP12,PRRX1,POLR2F,DRAM2,PPARA,PPP2R5E,PRKAB2,MAPK9,HYDIN,MASP1,SIDT1,GON4L,CNTLN,UHRF1BP1,C1orf109,PEX2,TMEM231,SLC25A48,FAM66C,RALGDS,RASGRF1,TRIM68,PRRT2,RIC8B,DCUN1D2,C12orf49,EPHA10,KIAA0895L,MCMBP,PAQR6,MEG3,ABCA11P,ST6GALNAC6,AMER2,SATB1,SCN2B,FAM19A1,PRCD,SCP2,TNFRSF19,TRIM46,GALNT10,RASA3,ITSN1,MYO18A,NTNG1,AMBRA1,FNDC3A,CNKSR2,WDR37,SLC1A7,FAM214B,SLC6A1,KANSL3,PKNOX2,LRRC55,SLC6A9,SLC8A2,SLC11A1,NAPB,SCMH1,LGI3,NAXD,GKAP1,MAST1,SORCS3,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,PDZD2,WDTC1,BDP1,ENKUR,ERC1,IDI2-AS1,SPTAN1,LHPP,ATP10B,SMOC1,SSTR1,ZC4H2,NKAIN2,INKA2,MAPK8IP3,MPRIP,CEP68,PHLDB1,GANAB,GSE1,NSFL1C,FGD4,ARC,SYT1,SYT4,MTCL1,FAM208A,PDLIM2,CNTN2,TBCEL,SATB2,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PMS2CL,CRB1,TGFBR3,ARL10,ENHO,TIAM1,TLR4,ERCC6L2,TMOD1,DAAM2,PRRT1,RBFOX2,ZNF346,PRMT8,AMACR,TRO,STXBP4,TRPS1,KCNE5,TUBB1,HEPACAM,FAM155A,UGT8,VAV1,VLDLR,WIPF1,NSD2,SLC13A3,ZIC1,ZNF45,GPR158-AS1,CRB2,AMZ1,TMEM198,ZNF213,DNALI1,SLC38A1,STMN4,PRDM8,SEMA3B,URM1,SNX27,FZD3,DOCK8,PAK5,CASC15,FAM219B,TIGD6,RNF170,ADAMTS10,SOCS4,LAS1L,JPH3" MicroRNA hsa-miR-18a*:mirSVR_lowEffct hsa-miR-18a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.42E-164 3.61E-160 3.28E-162 3.02E-161 433 1870 "EMILIN3,CSMD2,XKR4,SLC25A25,ADAR,ADCY2,ADD3,ADORA2A,KIAA1211,RNF150,PTCHD1,SLC24A4,SNX32,PCDH19,KIAA1324,TXNDC16,ZNF578,MRTFA,CDC42BPA,ANK1,ANK2,ANK3,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APLP1,DGKD,ALS2,DDO,PHYHD1,SHTN1,ARHGDIA,RGS20,ARRB2,LINC00173,CDK13,STK33,PCDHGB4,ASTN1,CCDC181,N4BP2L1,MYOM1,ADAM15,BCL2L2,BID,CFLAR,ARHGEF7,MYRF,BAIAP3,CA8,KALRN,PTBP2,ARHGEF25,CBR1,P2RX6,ENTPD6,LRBA,LRRFIP1,LARGE1,RAB33A,ZFYVE9,MYL6B,FAM19A5,C4orf33,QKI,IGLON5,PICK1,IQCK,FAM149A,SLC25A27,RCHY1,COX4I1,MFSD4A,CHD1L,C2CD2,ENTPD4,SH2B1,ANKRD44,CSF2RA,SEC24C,SUSD5,RIMS4,CNTNAP2,PLXNA4,SLITRK5,NRSN1,RIMS2,PPP6R2,RUBCN,CYBB,HDAC9,MYADM,FRMPD4,GIT2,DNAL1,ELMSAN1,C8orf34,ZEB2,B3GAT3,POM121,PLPPR4,SRGAP3,CCDC3,DPH1,DRP2,RCAN1,ABCC9,GOLT1B,FAM135B,ANKRD46,SGK2,HIPK3,FCF1,EFNA3,MBNL2,EGR3,GOLGA7,SORBS3,CERCAM,SRPK3,C3orf18,EML1,PAN3,DCTN4,EPB41,RASGRP2,NCALD,SPEG,CDHR1,DUSP27,ANKMY1,CEND1,MRVI1,CLVS1,FABP7,ZSCAN30,STRADA,GORAB,GTF2IRD2,FGF11,TMEM164,MAD2L2,SCARA3,HPCAL4,FOXF2,IP6K2,AGAP3,FOXO3,ATP13A4,WDR83,POMT1,TMEM107,SPECC1,ARFGAP2,ZNF605,ERGIC3,KHDRBS3,NSG2,CGREF1,PNMA2,ADGRA1,TMEM151A,AP4B1,SDCBP2,MEGF11,DKK3,GABBR1,GABRB1,BRPF3,NEK6,SEPT9,GCNT2,GPR162,CYP46A1,SESN1,HEPN1,KIRREL3,GJB1,RUNDC3A,CRCP,RNPS1,MSL3,AIFM3,OS9,WDFY3-AS2,GOLGB1,GPD1,GPD2,PRUNE2,LILRA2,PLCD4,PLPP7,GRIK4,ADAMTS8,GRM7,CIT,CLASRP,BVES,RNFT2,ATOH8,PTGDR2,NCKAP1L,VSIG4,HMGCL,OPALIN,HTR5A,IRF8,FAM95B1,C2orf72,RBPJ,DOCK7,DISP2,USP54,IL12A,ITGA7,GPR62,KCNH2,KCNJ9,KCNK1,SYTL4,ASPRV1,CLEC18A,LOC100128239,MAN2A2,MAT2A,MATN2,MBD1,SYT9,MEF2C,MEIS2,AFDN,MPP2,NDP,SFR1,RCOR2,NELL2,NME4,VWA2,SLC11A2,TBC1D25,IGSF11,OCRL,OGDH,P2RX7,ZNF827,ZDHHC22,PAK3,PBX1,PCDHGC3,PDE2A,PDE4B,PDE4D,PDE1B,PFKFB4,NALCN,SEMA5B,PIK3C2A,PIK3R1,ZNF655,GPSM2,PLEC,FTO,PNMA3,SCHIP1,FSD1,TMEM235,PTPA,PPP2R5E,KANSL1,NKAIN4,PRKAB2,MAPK3,MAPK9,SLC22A23,WBP1L,DEF8,PTAFR,PTN,ZSCAN32,PTPRG,PTPRN2,PTPRO,TUG1,TMEM255A,IQSEC3,NWD1,ZCWPW1,OXR1,RASGRF2,RFX5,KIF7,LGI2,TMLHE,C12orf49,GSTCD,BAALC,KIAA0895L,GLDN,PAQR6,RTKN,SATB1,ATXN7,SCN2B,SCN8A,PRCD,ASIC4,SEC14L1,GALNT10,STUM,FOXRED1,SFPQ,MRAS,TRA2B,COPZ1,NLGN4Y,SH3GL3,FERMT1,ASAP3,HKDC1,MAGI3,AMBRA1,CHD9,R3HDM2,CNKSR2,ST3GAL3,URGCP,EPN2,SLC6A1,PKNOX2,SLC6A8,SLC8A2,SLC9A5,SLC11A1,SCMH1,SLCO1A2,SLC22A4,CXXC4,SMARCA4,SORCS3,SNRPN,PALLD,SOX2,ZSWIM8,NMNAT2,MYCBP2,ZNF423,SPTB,TSPYL2,NFASC,MESP1,SMOC1,LARP4,INKA2,ZSCAN29,ADHFE1,STX1A,AJAP1,VAMP1,ARHGEF9,TMEM150C,ARC,SYN2,UNC5D,ALG1,ADGRL3,ATMIN,WSCD1,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TNS2,HIF3A,SPX,TGFBR3,ZNF34,TK2,DAAM2,CABIN1,TNS1,NPL,TPM2,ZNF346,SMUG1,TRIO,TRPS1,NUTM2A,PPIL6,RUSC1,TSC1,ZKSCAN5,TMEFF2,EIF4ENIF1,SLC35A4,LINC00689,BCL2L13,MTCH1,CCDC136,RBFOX3,LAT2,WRN,XRCC4,ZNF32,ZNF45,FMN2,PCBP1-AS1,FTSJ1,WNK1,PMEPA1,PARP6,STOX2,CIAPIN1,PCDH15,SLC17A7,WIPF2,PDSS2,KAT6A,HNRNPA3,CAMK1G,FAM219B,ZNF248,FAM198A" MicroRNA hsa-miR-1197:mirSVR_lowEffct hsa-miR-1197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.63E-164 5.41E-160 4.88E-162 4.49E-161 429 1838 "TTYH1,KCNH8,CLK4,NCKAP5,SYS1,CSMD2,XKR4,SLC25A25,CSMD3,NDRG2,ADD1,SLC12A5,SORCS1,USP31,UNC5A,KLHL13,HACE1,TAOK1,USP35,ALCAM,BCAR3,ARHGAP20,MARCH4,LCORL,CNTNAP1,GPAM,DGKD,LRRC4C,MIER1,SEMA4G,PDXK,IGDCC4,TMEFF1,ASPH,NUMB,DDX3Y,ALDH4A1,SLC4A4,ATP2B1,ATP2B3,N4BP2L1,ATP6V0A1,ADAM15,LINC00847,BCHE,KSR1,CA12,CACNA1A,CACNA1B,PTBP2,CAMK2G,VSTM2A,CAST,ISPD,TMEM257,SYNGR3,ENTPD6,MYOM2,REPS2,LGI1,MAGI1,CACNA2D2,CFL2,FOXN3,CHM,CHN2,CHRM1,JAM2,CPNE6,NRXN3,KIAA1549L,DGCR9,SRP14-AS1,TMEM155,CNTN1,IQCK,AKAP6,AKAP5,MFSD4A,CHD1L,SLC35F1,PREPL,CREB5,HAPLN1,NCOR1,ABCG1,CS,CSF2RA,OSBPL3,CHD5,VAC14-AS1,PDE4DIP,PLXNA4,CTNND1,ZSCAN23,MYADM,EARS2,LONRF1,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,ZBTB24,PLEKHM1,MFAP3L,KLHL3,LYPD1,SGSM2,G3BP2,TMCC2,ARNT2,SLC29A4,DYNC1I1,DPP6,PDCD6IP,DTNA,ECM2,ABCC9,WDPCP,RBM12,APH1A,MBNL2,KMT5B,PCOLCE2,ELN,ENO2,RCAN2,DMTN,LRRC17,EPHB1,ERBB2,ZNF549,SPEG,TMEM74,EXTL1,EZH1,SCML2,RACK1,CEP78,FCGR3A,FCGRT,FGF11,SPSB4,FGF13,FGFR1,CAMSAP1,FOXG1,SEC23B,ANKFY1,WDR83,PDLIM5,CAMKK2,ZNF605,KHDRBS3,ZNF512,FYB1,ZMAT1,STAG2,DKK3,GABRB1,HBS1L,ZMYND11,JPH4,ARPP21,GHDC,DISC1,SEPT9,INPP5K,CPLX1,MYOZ2,GFAP,GFER,PCDH17,BRD8,ZNF276,RNPS1,RAB30,MSL3,PCDH11X,DCLK2,GNAS,GPD1,DIPK1C,TDRKH,GRIA2,DIDO1,RFFL,GRIK3,GRM1,GRM5,BTN2A1,KIF3A,TMEM25,GSTT2,LINC01551,IRAK3,RASSF8,FRMD5,HMGB1,GABARAPL2,HMGCL,NEGR1,OPALIN,LRRC75A,SHISA6,ICA1,EID2B,IGFBP1,LRRCC1,IL6ST,IBA57,LRRTM1,SLC35G1,KCNJ10,KHK,KIF5A,KIF5C,STMN1,HECTD2,ARHGAP12,ZFYVE27,MAP6,MARK1,MBD1,MBP,LDLRAD3,TM6SF1,MDM4,KITLG,PPM1L,POC1B,AFF1,MPP2,PTOV1,CTNNA3,C10orf105,LYRM9,MYO7A,NCAM2,ZC3H12B,NDUFA5,RCOR2,NFIX,NNAT,NOVA1,DNHD1,SMIM11A,NUCB1,NUCB2,OCRL,OPCML,OPHN1,PAX6,PCDH9,GPR85,PFKFB3,HERC2P3,NLGN3,CAMKV,PIK3C2A,PIK3CD,SNX10,KCTD15,FTO,PLIN1,SMOX,MTRF1L,PMP2,TRHDE,CDIP1,LRP12,PRRX1,SPATA6,RETREG2,CRLS1,PPP2R5C,PPP2R5E,MAPK9,MAPK10,MASP1,RELN,CNTLN,PTK2,PTPRB,ZSCAN2,RAD51D,ZNF793,IQSEC3,RASGRF1,RASGRF2,BSDC1,SLC6A15,CRTAC1,DPF2,RGS12,RNF220,RIC8B,MYH14,C12orf49,RORB,BAALC,GLDN,SGSM1,PRR5L,STK32B,SYNDIG1,ABCA11P,WLS,NCBP3,SATB1,CSRNP3,SCN2B,SCN7A,PRCD,GALNT10,COPZ1,PPP1R9A,SH3GL3,FERMT1,ASAP3,MYO18A,NTNG1,SLITRK3,ST3GAL3,SEC31A,PAAF1,SLC1A3,PPP4R3A,LIMS2,KANSL3,SLC11A1,SLC12A2,SLCO1A2,TET1,CPEB4,NAXD,SMARCA4,INTS9,SMARCE1,INAVA,LIMCH1,SNRPN,DOP1A,NMNAT2,ENKUR,LHFPL4,MYCBP2,TEX2,ZNF423,RAP1GAP2,NFASC,C11orf87,ATP10B,CLASP2,ITPRID2,LARP4,ZSCAN29,TTBK2,STAC2,FAM168A,ARHGEF9,DNAJC9,SYN1,COBL,MTCL1,UNC5D,CNTN2,ATMIN,TCF4,TCF12,SYNE1,CYB561A3,TEK,FAM200B,LEFTY2,AP4E1,CDH22,FBXL16,TK2,ACTR6,ANKRD24,PIK3R5,RBFOX2,RASD2,TPM1,WBP2,ZNF384,TRO,TTTY15,CLHC1,TUBB1,HEPACAM,CADM1,EIF4ENIF1,UCHL1,GORASP1,OSBP2,CCDC14,VLDLR,TBC1D15,NSD2,WRN,RICTOR,ZNF19,ZFP41,ATP6V0E2,PLPP4,CRB2,LYPD6,POLR3H,EMSY,CSDE1,XKR7,RNF103,CAB39L,SLC17A6,FAM13C,MARCH8,CASC15,CERS6,ACTR3B,FAM219B,VANGL2,NHSL1,ZDHHC20,SLC39A12,IFT88,FAM198A" MicroRNA hsa-miR-452:mirSVR_highEffct hsa-miR-452:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-163 9.14E-160 8.16E-162 7.52E-161 417 1740 "RALGAPA1,KCNH8,ACADM,CLK4,ACTN2,CSMD3,ADD3,BRAP,BEND6,NLGN4X,SLC44A5,AP2A2,TAOK1,LRRC7,SEMA6A,MARCH4,FAM135A,SYT13,ZNF687,ZFAT,OGT,ANK2,USP28,PPFIA1,API5,SHROOM2,CASK,ASCL1,MARCH3,ZBTB10,ATP1B3,ATP2B1,B3GALT2,MYOM1,DOCK11,BACH1,ADGRB3,BBS2,KSR1,SYNJ1,FUBP1,JAZF1,OSGIN2,CA8,CACNA1E,CAMK2G,CANX,CAST,SPAG9,CLDN10,KRIT1,SLC16A4,CDC27,CDC42,CDH2,CDH18,TIGD7,CHN1,NDST3,EPS15L1,ZFYVE9,FAM19A5,C4orf33,QKI,MAP4K4,ARHGEF6,CNTN1,BTF3L4,AKAP5,ABI3BP,RTTN,CLOCK,ARHGEF10,SIPA1L1,PLXNA4,FAM169A,ERC2,DOCK4,HDAC9,FGFR1OP2,FRMPD4,MATR3,DGKB,GIT2,YTHDC1,MYEF2,HP1BP3,GSDME,GUCD1,RHOBTB1,SPOCK3,NTM,G3BP2,RABGAP1L,ZNF582-AS1,CHRDL1,DLX1,GRIN3A,DMD,CPEB2,DMTF1,CASP8AP2,DPYSL2,ABI1,DTNA,ECM2,FAM78B,DUSP9,DYRK1A,GOLT1B,EDNRA,ANKRD46,HIPK3,RASGRP1,KLHL5,TMTC1,FRY,YAF2,PHF20L1,EGFR,KMT5B,TENM1,ELAVL2,ELAVL4,CALCRL,PAN3,EPB41L1,SRRM1,EPS8,ADGRV1,FAM198B,FABP7,EFEMP1,CEP78,ZSCAN30,FER,FGFR3,AMOTL2,SYNCRIP,JKAMP,SPECC1,ATP6V1H,ERGIC3,DACH2,AP4B1,SDCBP2,PHYHIPL,ZMAT1,DKK3,GABRG2,CAB39,SALL3,IP6K3,GAP43,TMEM8B,DISC1,KIAA1841,MSTN,NFU1,PPARGC1A,GK,TXNL4A,CRCP,COPS8,GPR75,GLS,TOX3,PCDH11X,GPM6A,TDRKH,GPR22,CNTRL,GRB10,GRIA4,GRM3,PSIP1,MAP4K5,MAEL,HAS2,IGSF21,FRMD3,ELOVL5,HNMT,IGFBPL1,C9orf129,DHX35,IRF8,SOWAHA,C5orf24,RBPJ,DISP2,USP54,SCIN,IL6ST,DIPK1A,ZNF385B,KCNK2,IPO5,LAMP2,LIG4,LIMS1,PAXBP1,VWA5A,HECTD2,FGFBP3,ARHGAP12,NCOA7,MAP6,MATN3,MBNL1,IL17D,LDLRAD3,TM6SF1,LRP1B,MEF2C,MRPL42,ADAM22,MTTP,NAP1L3,SFR1,NF1,NPTX1,NRCAM,NUCB2,GLIPR1L2,SNTG1,PAK3,CNTN3,DPY19L2P2,ETFRF1,PCSK1,PDCD2,SERPINE2,SERPINI1,FAM218A,CCSER2,RETREG1,KCTD15,STRN3,SCHIP1,POU6F1,TMEM235,MED1,PPM1B,TATDN3,PPP2R5C,PPP3CB,CEP41,PKN2,MAPK9,RELN,CNNM2,SAMD9,LRRC49,APTX,SYTL2,SNRK,ANKHD1,MTMR10,PTHLH,PXK,PTPRG,PTX3,PEX2,PPP2R3C,PID1,CEP97,TMEM255A,FAM66C,RASGRF2,ARID4A,RADX,SLC6A15,ZYG11B,REV3L,ERI2,SEC61A2,RNF220,PBRM1,RNASEL,ZNF532,CARF,ROBO2,MRAP2,FBXW7,SPIN3,KIAA0895L,MCMBP,ATP8B4,LRRK2,SYNDIG1,KCNIP1,ZNF354C,LINC00461,SCP2,TRA2B,SH3GL2,FBXO11,FNDC3A,CTXN2,CLSTN1,PREX2,KANSL3,PKNOX2,SLC8A1,SLC8A3,ARHGEF40,CCDC88A,BTBD7,SLC22A4,CPEB4,ZFP1,SMARCA4,SMARCE1,RCOR3,ANKRD36,LIMCH1,MBD5,TMCC1,PDZRN3,UNC80,SON,MYT1L,BDP1,SOX15,SP4,ZC3H13,SPART,SRPK2,ATP10B,POGZ,EPB41L3,NKAIN2,SS18,ERBIN,NXT2,NEK4,SEPT8,KANK1,NSFL1C,NECAB1,SYNE2,ARHGEF9,VPS13A,C3orf70,SYPL1,TAC1,MTCL1,PJA1,TBCEL,KLHL4,VWA3A,TCEA1,SATB2,CUX2,ZEB1,WDR7,DOCK9,GPRIN3,FRYL,FAM200B,ITGB3BP,HHIP,SLC44A1,GZF1,TLL2,ERCC6L2,RIMBP2,TP53BP2,TPM1,C9orf85,RGMB,TTPA,CADM1,UBE3A,GORASP1,FLRT2,FAM181B,USP1,WIPF1,WRN,XRCC4,LGI4,ZIC3,ZNF19,ZNF23,MICU3,AGMO,FMN2,GPR158-AS1,MKRN3,LYPD6,TCEAL7,ZNF142,EML6,ANKS1B,TFIP11,UPF3A,WNK1,SLC30A4,EMSY,CADM2,NAV3,PPP1R3F,FIP1L1,SLC17A6,FAM13C,KAT6A,HNRNPA3,PHTF2,NUP214,ACTR3B,ZNF248,KLHDC1,IFT88,NETO1,SLC4A10" MicroRNA hsa-miR-544:mirSVR_highEffct hsa-miR-544:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.83E-163 1.59E-159 1.41E-161 1.29E-160 442 1954 "ACADM,ACLY,NBAT1,CSMD2,XKR4,AXIN2,SORCS1,PWWP2A,RNF150,PTCHD1,ADRB2,BEND6,SLC44A5,HECW2,PCDH19,HACE1,OSBPL1A,OSBPL8,CC2D2A,AK2,SEMA6A,SPOP,ALCAM,ARHGAP20,PCDH10,DPP10,LCORL,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,GPAM,TNRC6C,AQP6,TMEM263,ARNTL,PLA2G4C,ASPH,NCOA1,ATM,ATP1B3,ATP2A2,N4BP2L1,ADAM23,BACH1,BBS2,MPDZ,BCHE,PROM1,KSR1,DST,ARHGEF7,LINC00906,GYG2,CACNA1G,CA8,CACNA1A,CACNB4,CALB2,KALRN,CAMK2G,PRC1,ZNF501,CBFA2T2,DGKI,LRBA,CDH2,LRRFIP1,CDH18,CDO1,CHN2,CASC2,SYNPR,NDST3,NRXN3,QKI,NIPBL,CNGA3,TMEM155,ARHGEF6,AKAP7,PCYT1B,FAM149A,AKAP6,LETMD1,AKAP5,ZFP28,CHD1L,PREPL,CREM,RBM39,HAPLN1,GDA,TENM4,RGS6,CSF2RA,ARHGEF10,ATRNL1,SIPA1L1,NCAN,PDE4DIP,DZIP3,PHF14,PNPLA8,CFAP61,CTNND1,DCAF4,GPRASP1,GAPVD1,RIPOR2,TOX,LIN54,TMEM170A,DAPK1,TOMM20,DCC,C8orf34,ZEB2,KIAA0753,COPS7A,SMG7,SACS,RABGAP1L,FAM107B,EXOG,CPEB2,SLC12A6,ABI1,PDCD6IP,ARRDC4,DTNA,ECM2,MAMLD1,DNAJB6,DYRK1A,ABCC5,DNM1L,ABCC9,EDNRA,HIPK3,SYT15,RASGRP1,FRY,MBNL2,AASS,GOLGA7,COPS4,DCTN4,STX2,IGSF6,GMPR2,ACSL4,SCML2,EFEMP1,FDFT1,FER,KIAA1109,FGF12,FGFR1,CAMSAP1,SEC23B,SYNCRIP,SORBS1,TMEM107,SMC2,SPECC1,HVCN1,APOPT1,PDLIM5,STAMBP,ST6GALNAC3,SARAF,STAG2,DKK3,MEGF10,GABRA1,ZNF44,GABRB1,GAD1,ZMYND11,SALL3,ZNF234,ERAP1,SEPT9,INPP5K,LRRC37A6P,GATM,FREM1,LYVE1,TCERG1,COPS8,GLI2,TOX3,TNRC6A,PCDH11X,CBX1,KDM2B,HTATSF1,GPD2,GPM6B,CCDC184,PCLO,GRIA1,GRID1,GSTM5,KAT7,AP4S1,ADAMTS6,RASSF8,UBE2QL1,HPS5,BACH2,HLF,TCEAL6,SMAP1,HTR5A,SOWAHA,RBPJ,DOCK7,KIAA1755,ZNF678,ITGAV,C2CD4C,OLFM3,KCNA4,KCNJ3,KLHL23,KCNK2,KCNMA1,KLC1,IPO5,PAXBP1,FGFBP3,NCOA7,CLEC18A,MAP2,MAP6,MEST,KITLG,PPM1L,WDR49,MOBP,ADAM22,MYO9A,NAP1L3,NASP,NELL2,NF1,CNOT4,NOVA1,OCRL,GPR88,OLR1,CNTN3,PCDH9,PCSK1,PDE1A,PDE3B,PDGFRA,GPR85,GNG2,OLA1,CDK14,SERPINE2,CAMKV,XRN1,PLP1,SPATA6,EPB41L4B,POU3F2,CRLS1,PPP2R5E,PPP3CA,RANBP3L,PRKACB,GRAMD1C,RELN,CYBC1,SYTL2,MDGA2,PIGG,CNTLN,ANKHD1,BDNF-AS,PTN,TMEM260,PTPRG,ACSM5,ZNF615,PPP2R3C,MARCH1,RAD51D,FAM66C,FAT4,NWD1,RASGRF2,RDX,SLC6A15,ZYG11B,RET,RFX3,RGS7,TTLL7,RIC8B,TMLHE,ROBO1,ELP2,RPE,NEK11,FBXW7,ZC3H14,MCMBP,ATP8B4,ACER3,STK32B,CNTNAP3,ATAT1,NCBP3,AMER2,SATB1,FAM19A1,SCN8A,HSPA4L,SCAF8,NLGN4Y,ZFP30,ITSN1,SH3GL3,CPEB3,NTNG1,SHC4,FBXO11,FNDC3A,CTXN2,EPN2,WDR47,RUFY2,LRRC55,SLC9A5,SLC15A2,SLCO1A2,SMARCE1,ANKRD36,RIMS1,SNRPN,MYT1L,TNIK,KDM3A,SP4,EMC1,KDM4C,RBM26,NPAS3,RAP1GAP2,NFASC,ATP10B,CLASP2,POGZ,EPB41L3,NKAIN2,LRRC4,ZSCAN29,RGL1,NSFL1C,FGD4,PLCB1,COBL,MMS19,ATP11A,ANKRD12,TAF9,CAMSAP2,ADGRL3,KIAA1107,TBCEL,TBL1X,ANO4,TCEA1,ZFP90,TCF7,ZEB1,CLASP1,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,HIF3A,SIK3,PMS2CL,CRB1,ITGB3BP,AP4E1,AKTIP,GZF1,ASXL3,NR2E1,ERCC6L2,TMOD1,TPD52,TPM1,C9orf85,SYNPO2,RUNDC3B,TRPC1,PPIL6,TTTY15,TTC3,TUBB1,CADM1,FAM155A,AMOT,UGT8,FLRT1,CCDC136,MEAF6,WIPF1,NSD2,SF1,ZBTB14,KCNT2,FMN2,GPR158-AS1,ZBTB38,ZSCAN26,SPIRE1,PLPPR5,NT5M,CSDE1,RNF103,ADAMTS9,FIP1L1,DNAH10,PAK5,CASC15,TRAM2-AS1,KLHDC1,GAN" MicroRNA hsa-miR-34a*:mirSVR_lowEffct hsa-miR-34a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.44E-163 2.50E-159 2.19E-161 2.02E-160 429 1845 "CLK4,ACTN1,ACTN2,NDRG3,ADARB2,ADD2,SORCS1,RNF150,KLHL13,TBC1D14,OSBPL8,HFM1,SPOP,SRPX,PCDH10,UNC79,FAM135A,GPRASP2,AMT,ZFAT,OGT,MAP4K3,PPFIA1,BCAS1,TNRC6C,USP37,APP,PPP4R4,TMEFF1,ARHGAP5,CDK13,PCDHGB4,ZBTB10,NCOA1,ATP2A2,ATP6V1G2,TTLL9,BCL7A,DST,SYNJ2,ARHGEF7,WASF1,IL33,BTRC,CALB1,CAPN3,CAST,AIFM1,TMEM257,CDH2,LRRFIP1,DLGAP1,CIART,CASC2,NRXN3,PPT2,C4orf33,QKI,TMEM184B,SRP14-AS1,NIPBL,ARHGEF6,CNTN1,IFFO1,ACBD5,ZFP28,NRG2,CHD1L,PREPL,SLC32A1,CSF1R,ARHGEF10,OSBPL3,SOCS5,SLITRK5,PHF14,NRSN1,PUM1,RUBCN,KCTD8,DGKB,TMEM170A,ZNF804A,C8orf34,MFAP3L,CEP170,SV2A,SRGAP3,NTM,TMCC2,WDR20,DLG2,DLX1,DMTF1,ACOT8,DSCAM,DTNB,DNM1L,E2F5,EDN3,EDNRB,ATL1,FAM13A,KMT5B,ABI2,ELAVL2,CALCRL,VPS13B,LRRC17,EPHB1,ZNF549,ETV1,DUSP27,RCSD1,RASL12,NRN1,F5,FAM198B,WAC,TAOK3,ATP8A1,FCGR3A,TOMM40L,OLFM1,FGF12,FGF13,TMEM164,SUCO,UBE2E3,IP6K2,SYNCRIP,C2orf88,EFCAB2,PDLIM5,TPK1,CAMKK2,KHDRBS3,NSG2,CELF1,DACH2,MSANTD4,SARAF,ZNF512,OGA,FYN,PHYHIPL,ZMAT1,GABBR1,GABRA2,CHL1,TRAF3IP2,ILDR2,HBS1L,FAM120B,MTHFD2,KIAA1841,DNER,ADAM28,GFRA1,USP19,HPGDS,TOX3,TNRC6A,MSL3,PCDH11X,ZNF638,ADGRA3,GPD2,PRUNE2,FUT10,CCDC184,STON1,GPR37,GRIK1,NR3C1,GRM1,KIF3A,RNF165,PTPN5,LINC01551,AP4S1,FAM107A,WIF1,RASSF8,UBE2QL1,HPS5,ARHGAP36,MIER3,AGBL5,ZDHHC15,NEGR1,TCEAL6,CELF5,HTR2A,LINC00667,NKD1,IGSF1,SCIN,HES5,IL11RA,RIPPLY2,LRRTM3,ITGAV,KCNA1,KCND1,KCNJ3,KTN1,LAMA2,LMO2,SYTL4,HECTD2,FGFBP3,PIK3AP1,ZFYVE27,MAP2,MAPT,MBNL1,SYT9,ADAM11,MDM4,LRP1B,MID1,PPM1L,CPNE9,N6AMT1,SCG3,RSPO2,MYCN,NEXMIF,TCEAL5,BEX5,NEK1,NF1,NFE2L2,NNAT,NOS1,NOVA1,SLC11A2,OGG1,CLDN11,PCDHGC3,PCDH9,PCMT1,PDE4A,ENPP2,PDYN,SEMA5B,PIK3C2A,TMIE,ZNF655,FAM218A,XRN1,PLCL1,PLXNB3,PMP22,MAPKAP1,LRP12,EXOSC10,PRRX1,ING3,EPB41L4B,NXPH1,DRAM2,CRLS1,PPP3CC,PRKCB,VPS13C,MDGA2,PSMD13,ANKHD1,PLPPR1,TMEM260,STK32A,PTPRB,STRC,FAT4,RAP1GDS1,RASGRF1,RBBP6,KHDRBS2,RFX3,RGS3,RGS12,MRPS18A,KLHL11,SEC61A2,PBRM1,ZNF532,ROM1,PCMTD2,RPE65,TMEM100,FBXW7,BAALC,SPIN3,ATP8B4,RPL38,ZNF331,TRAPPC13,AP1AR,SATB1,ATXN2,ATXN7,HOGA1,LRRTM4,SCP2,SLC30A10,SOX6,MRAS,TRA2B,FRMPD1,MAGI3,CHD9,SYBU,ST3GAL3,SLA,KANSL3,PKNOX2,SEPHS1,KBTBD4,SLC15A2,SLCO1A2,SPHKAP,SLIT1,CPEB4,MYH15,RIMS1,SNAP25,KDM4B,DOP1A,SON,PDZD2,WDTC1,SOX1,MYT1L,SOX5,DOK5,ZSWIM8,EMC1,PEG10,ZC3H13,BEX1,C11orf87,SRPK2,EPB41L3,ZSCAN29,CEP68,STAC2,AJAP1,SYNE2,C3orf70,PLCB1,TACR1,PJA1,TAF9,ALG1,KIAA1107,TMEM136,TBX15,VWA3A,ACSL6,VWC2,TCF4,SATB2,TCF7L2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,PCDHB10,NSD1,GPRIN3,SLC35G2,DICER1,CRB1,ITGB3BP,AKTIP,SLC44A1,TLL2,TMOD1,RBFOX2,CDK20,NPL,NEIL2,TRPS1,TTPA,PRR18,CLHC1,EIF4ENIF1,UCHL1,PITPNB,FLRT2,MEAF6,CCDC14,TBC1D15,WIPF1,GUSBP1,ETNPPL,CFAP298,SLC47A2,ZIC1,ZIC2,KCNT2,REEP1,CA10,EMSY,PRDM2,CSDE1,SCG2,PCDH15,KCNAB1,PDSS2,JMJD1C,TIGD6,KLHDC1,IFT88,SLC4A10,LAS1L" MicroRNA hsa-miR-362-3p:mirSVR_lowEffct hsa-miR-362-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-163 2.81E-159 2.42E-161 2.23E-160 423 1795 "VWA5B2,RALGAPA1,ABCF1,KCNH8,CLK4,FAM43B,ARID1A,CSMD3,CCDC85A,ADD1,KIDINS220,CC2D2A,TAOK1,SMIM17,SEMA6A,ALCAM,ABCD2,AMPD2,DPP10,FGD2,PPFIA4,PKP4,APBA2,FAM131A,PHYHD1,SHTN1,SHROOM2,NCOA1,NUMB,DDX3Y,INSYN2B,ATM,SLC2A11,RNF182,CADM3,NOL4,ADAM15,ADGRB2,SNAI3-AS1,NRP2,BMP7,FUBP1,NAE1,BTK,GYG2,BAIAP3,LDLRAD4,CFAP410,CACNA2D1,CALM1,KALRN,CAMK2B,VXN,CLDN10,LDB2,METTL6,USP6,CD81,CDH10,DCLK1,LGI1,L3MBTL4,CCPG1,NOG,NUMBL,CACNA2D2,B4GALT6,LSMEM2,CPNE6,KIAA1549L,CLCN4,HECTD1,NIPBL,CNR1,AKAP7,SLC4A7,AHCTF1,RTTN,CREM,CRY2,HINFP,SLC32A1,ANKRD44,GDA,CSNK1E,SUSD5,PLXNA4,SLITRK5,DZIP3,ERC2,APPL1,CFAP61,CTNND1,ST18,CX3CR1,NOS1AP,FRMPD4,HDAC4,TOX,RASSF2,MATR3,SPOCK2,DNAL1,ZBTB24,HP1BP3,MED24,GSDME,PLPPR4,SNAP91,SACS,SV2B,SRGAP3,AK5,G3BP2,WDR20,CHRDL1,EXOG,GRIN3A,DMD,DMPK,CASP8AP2,PDCD6IP,DTNA,MAMLD1,ABCC5,ABCC9,CNNM1,SEMA3D,RBM12,APH1A,KMT5B,EGR3,TENM1,EN2,EPB41L2,DMTN,EPHA5,ENPP6,GPHN,ERBB2,DENND4A,DLC1,PRKAG2,PCYOX1,SYNCRIP,RGPD5,FOXO3,COQ5,SMC2,FAM49B,NPTN,ARFGAP2,ZNF605,ERGIC3,NSG2,CELF1,DACH2,CGREF1,NSG1,STAU2,NRG3,ABLIM2,CHL1,GABRG2,GAD2,GALC,NCKAP1,TMEM8B,ATP8A2,CPLX2,MYOZ2,SESN1,BRD8,TXNL4A,TCERG1,CBX1,GNAO1,ZNF782,GPT2,ADGRA3,PRRC2B,LILRB4,PRUNE2,CCDC184,MCHR1,GPR34,NUDT21,PCLO,GRIA2,DIDO1,RFFL,GRIK2,ADAMTS13,GRM5,RNF165,GSTM5,MFSD2A,AP4S1,PSIP1,WIF1,ARHGAP19,IGFBPL1,HSD17B1,IRF8,MSL1,C5orf24,RBPJ,DOCK7,TMEM240,IL11RA,ZNF678,ITGA7,KCNH2,KIF2A,STXBP5,LAMP2,LMO2,SYTL4,HECTD2,NCOA7,MAOB,MAP2,MARK3,MAT2A,CHIC1,MEIS1,MGAT3,MOBP,MRPL42,JAKMIP3,MDGA1,LYRM9,MYO7A,MYT1,NAP1L3,P2RY13,NCAM1,NEK1,NFIA,NHLH1,NOVA2,NUCB2,NUMA1,OPCML,GPR137C,PALM,CNTN3,PCMT1,PDCD2,SSH1,NALCN,CAMKV,GPSM2,PRIMPOL,MAPKAP1,CDIP1,RC3H2,LRP12,EPB41L4B,TNPO2,FAT3,NXPH1,POU3F2,PPM1B,CRLS1,RASGEF1B,MAPK4,PROX1,PRPSAP2,VPS13C,PTCH1,UHRF1BP1,PTPRD,PEX5,RAD17,PLEKHB2,FAM66C,SH3TC2,RADX,KHDRBS2,ZDHHC14,RDX,REV3L,RGS7,RNF220,RIC8B,RPRD1A,RNH1,KLHDC8A,EPHA10,BAALC,ZNF671,SGSM1,MEG3,ST6GALNAC6,RTKN,ZNF331,DGLUCY,SATB1,ATXN1,FNIP1,CASC3,MRAS,FAM102A,FERMT1,NTNG1,MAGI3,SEC31A,DZIP1,ANKRD6,KANSL3,SLC6A11,SLC8A3,SLC12A4,NAPB,TMEM132D,ELMO2,SLC20A2,SLCO1A2,SLC22A4,CPEB4,CDK5RAP2,MYH15,SMARCE1,IFT122,SNRPN,PALLD,MYO16,UNC80,FAM219A,TRERF1,SOX2,TNIK,SOX5,ZCCHC24,KIF21B,BDP1,ZSWIM8,SP4,SPP1,KDM4C,ZC3H13,KIF1B,NPAS3,NFASC,POGZ,ITPRID2,SMOC1,EPB41L3,ZC4H2,MAPK8IP3,MPRIP,SEPT8,TTBK2,SULF2,AJAP1,ZC3H4,ADAMTS17,SYPL1,SYT1,COBL,CAMTA1,MLST8,TAL1,ADGRL3,AGTPBP1,TBL1X,ANO4,TBX15,SIN3B,DMXL2,ZFP90,TPCN2,USP22,AZIN2,SYNE1,NAT16,TNS2,CYB561A3,ITGB3BP,SLC44A1,TIE1,TMEM9,BHLHB9,ZFP91,BEX4,TP53BP1,ZNF346,PRMT8,PDSS1,NEIL2,TRPS1,SSBP2,CADM1,EIF4ENIF1,CLEC2L,AMOT,LMF1,XPO1,ZIC1,ZNF711,TRIM9,FMN2,TCEAL7,TMEM237,FSTL5,PLPPR5,SLC30A3,WNK1,PRDM2,LINC02210,RNF103,PCDH15,CAB39L,WIPF2,CERS6,VANGL2,MSRB3,TTC7A,SLC39A12,FRMD6,IFT88,ST8SIA2" MicroRNA hsa-miR-3171:mirSVR_lowEffct hsa-miR-3171:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.00E-163 2.81E-159 2.42E-161 2.23E-160 432 1871 "ACLY,KDM5D,CSMD2,KLRC4,ADD3,KIAA1211,PTCHD1,KIDINS220,SLC44A5,ZNF608,KCTD16,OSBPL1A,NME5,OSBPL6,WDR35,TAOK1,LRRC7,ALCAM,LRCH2,C6orf89,CCDC146,MAP4K3,ANXA7,APAF1,MAGEE2,NT5C3B,VAT1L,BCAS1,APP,LGR5,SLC7A14,IGDCC4,CDK13,ASPA,NUMB,ATP1A1,EIF4G3,ZNF582,MTMR9,B3GALT2,N4BP2L1,DOCK11,BBS2,FUBP1,SCAPER,C1QC,SGCE,WASF1,BTRC,CACNB4,PTBP2,TRIM41,VXN,ISPD,CBLN1,MTMR7,LRRFIP1,SRSF11,CASC2,MS4A7,KMT2C,NRXN3,KIAA1549L,CLCN4,CLTA,QKI,ARHGEF6,CNR1,ARMC8,AKAP6,COL4A5,COL9A1,SLC4A8,AHCTF1,ZNF521,FAM171B,CRHBP,CREB5,GDA,SEC24C,ATRNL1,PLCH2,NCAN,PLXNA4,KIAA0040,ST18,ZSCAN23,EDRF1,FAM131B,CCDC144A,ARHGAP32,GAPVD1,ARHGAP24,FRMPD4,ZFYVE16,EARS2,KIAA0586,TMEM170A,DAPK1,DBI,GIT2,SPATA2,YTHDC1,JAKMIP2,MYEF2,ELMO1,CEP170,MAGI2,FBXO25,SRGAP3,NTM,MTX3,WDR20,DLG2,HS3ST4,DNAH9,DYRK1A,GOLT1B,WDPCP,FAM135B,EDNRA,EDNRB,ATL1,HIPK3,FCF1,SEMA3D,TMTC1,FRY,EFNA3,FAM13A,MBNL2,ELAVL2,ELAVL4,EN2,VPS13B,EPB41L2,COQ7,LRRC17,EPHA5,ENPP6,GPHN,EPS8,DENND4A,NCALD,EFS,ZNF549,KATNAL1,EYA1,EZH1,CLVS1,ABCA8,FABP7,TAOK3,ATP8A1,SUCO,MEX3B,SYNCRIP,RGPD5,SLC37A3,TRMO,USP16,ATP2C1,PRELID3A,CELF1,SARAF,GAB1,GABRA1,FAM184B,HBS1L,AHCYL1,ZMYND11,NCKAP1,ZNF559,DISC1,GCNT2,CYP46A1,ADAM28,PCDH17,PPARGC1A,GK,DBF4,GLS,KDM2B,LUZP2,LNX1,ATF7,LILRA1,GPR22,GPR34,PCLO,GRIA1,DIDO1,GRM1,BTN2A1,LINC00839,MFSD2A,LINC01551,PADI2,FRMD3,ELOVL5,TCEAL6,IGF1,C5orf24,LRRCC1,PLD5,USP54,SCIN,BRINP3,ZNF678,INSM1,LRRTM3,SLC35G1,KCNC2,KIF5A,KIT,LMO2,PACRG,SMAD1,GPR155,MAP2,MARK1,LYPLAL1,MBD1,MDM4,MEF2C,MGAT3,CD200,MRPL42,MYO5A,MYO9A,HNRNPM,NAP1L2,SFR1,NEFH,NEUROD1,NFIA,OTOGL,NHLH1,CNOT4,DNHD1,NPTX2,NRCAM,NUCB2,OPA1,ZNF713,OXTR,PAH,PCDH9,PCSK2,PRTG,PDE3A,GPR85,GNG2,ZDHHC8,SERPINE2,ANLN,ZNF655,SNX10,PLCL1,PCDH18,MTRF1L,PMP2,PMP22,TRHDE,STRN3,LRP12,PSAT1,SLC36A4,PPM1B,PPP2R2C,LRRN3,PPP2R5E,PRKACB,DIRAS2,GDPD1,LRRC49,ANKHD1,PXK,SPDL1,PTPRB,OCIAD1,PTPRG,TUG1,RAD51D,FAM66C,ZNF793,OXR1,ARID4A,DBX2,FEZF2,MSANTD2,ZYG11B,RFX5,RGS4,SEC61A2,RIC8B,RPRD1A,ZFHX4,EXD2,RPE,TMEM100,NEK11,RPL15,ATP8B4,LRRK2,LGR4,RXRA,TRAPPC13,SAFB,SALL1,SATB1,IL17RB,FOXRED1,SUPT20H,ZFP30,PPM1E,CHD9,FNDC3A,FHOD3,NLGN1,SLC1A3,PPP4R3A,BTBD3,RUFY2,SLC6A1,SLC8A1,SLC12A2,MTERF2,SLC22A4,TET1,CPEB4,SORCS3,RCOR3,SNRPN,DOP1A,PDZD2,WDTC1,CLUAP1,UHRF1BP1L,KDM4C,ZNF423,TSPYL2,RBM26,ITPRID2,STOX1,LARP4,NKAIN2,DIP2A,AJAP1,NECAB1,SYT11,PRRC2C,VPS13A,ADAMTS17,C3orf70,SYT4,ADGRL3,KIAA1107,IQCE,ANO4,EHBP1,VWC2,DMXL2,SATB2,TCF7L2,ZEB1,TRIM2,RPGRIP1L,TCF12,CLASP1,PCDHB10,ARHGEF12,ARHGAP9,ATP13A2,DICER1,ZFPM2,CRB1,ITGB3BP,HHIP,GZF1,TIAM1,TJP1,ACTR6,TLR4,PRRT1,R3HDM1,TP53BP2,ZNF346,TRIO,PPIL6,RFTN2,TTPA,TMEFF2,SGK3,EIF4ENIF1,AMOT,SLAIN1,PITPNB,USP1,WIPF1,P2RY12,CLDND1,XRCC4,PCDH20,ZIC3,GPR158-AS1,NDRG4,ZBTB38,FSTL5,TMEM198,FTSJ1,DHX33,CA10,CADM2,SLC38A1,RNF103,MDH1B,NAV3,DNAH10,FAM13C,FZD3,CERS6,JMJD1C,RNF170,VANGL2,TTC7A,NHSL1,SNX14,NETO1,SOCS4,ST8SIA2,SENP7" MicroRNA hsa-miR-106a*:mirSVR_lowEffct hsa-miR-106a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-163 3.08E-159 2.63E-161 2.42E-160 435 1897 "ACADM,ASIC2,KDM5D,XKR4,CSMD3,NDRG3,PLEKHH1,GRAMD1B,KIAA1211,BEND6,SLC24A4,SLC44A5,PCDH19,HACE1,OSBPL8,CC2D2A,LRRC7,SMIM17,ANK3,EP400,CCDC146,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,APC,CACHD1,TNRC6C,SHTN1,LGR5,RGS20,MARCH3,MARK4,ZBTB10,DDX3Y,NOL4,BACH1,LINC00847,BBS2,CFLAR,KSR1,CACNB4,CACNG1,KALRN,CAMK2D,CANX,MAP7,USP2,TMEM257,SEPT7,REPS2,LGI1,DLGAP1,TIGD7,CLGN,NOG,RCBTB2,SRSF11,FOXN3,CASC2,SYNPR,CHRNA4,CNOT8,NRXN3,PLAA,NRXN1,STOML1,CLTA,SULT4A1,NIPBL,CNN3,ARHGEF6,SUMF2,AKAP5,MAGED1,SMARCAL1,TCEAL2,MYRIP,ZNF521,MFSD4A,CHD1L,SLC35F1,CDC42BPB,PREPL,CREM,ENTPD4,RBM39,RNF14,GDA,SNCAIP,CSF1,CSF2RA,LRIG1,OSBPL3,CSNK1G3,VCAN,SOCS5,PHACTR3,PHF14,CTH,CFAP61,NOS1AP,ARHGAP32,ARHGAP24,FRMPD4,LONRF1,LIN54,AIF1L,GIT2,SPATA2,ZEB2,TIAM2,HP1BP3,COPS7A,GSDME,GUCD1,SACS,G3BP2,DLG2,DLG3,DYNC1I1,CDON,DMTF1,CASP8AP2,DPYSL2,DSCAM,RCAN1,ARRDC4,DTNA,DYRK1A,AASDH,SNX29,WDPCP,ABI2,ASB3,C3orf18,EML1,CALCRL,EPHB1,KCNMB2,STX2,SPEG,DNAJC27,RCSD1,TBC1D16,ACSL4,ZIC4,TAOK3,SCML2,RACK1,ST3GAL6,STRADA,GORAB,FER,POLK,SUCO,FOXG1,CAP2,SYNCRIP,AGAP3,SEMA4D,FLT1,ANKFY1,JKAMP,NBEA,UFM1,ATP2C1,GPR153,STAU2,KBTBD12,MEGF10,GABRA1,GABRA2,GABRB3,TRAF3IP2,DENND2A,GAD2,GALC,C15orf41,TUBGCP4,SULT1C4,SESN1,ADAM28,MMADHC,RNPS1,TOX3,LUZP2,LNX1,GPM6B,GPR12,MCHR1,NUDT21,EML4,GRM5,LINC01551,RABL2A,SOX21,MAP4K5,CELF3,IRAK3,RASSF8,ZHX1,FRMD5,C9orf129,ZDHHC15,TCEAL6,ZIC5,RBPJ,INPP5B,INSM1,ZNF385B,NME9,ITGAV,JAK2,KCNA1,KCNA4,KCNB1,GPR62,KCNK2,KCNMA1,KIF2A,KLRC2,KTN1,LAMP2,LIFR,LIG4,PAXBP1,ARHGAP12,NCOA7,C2orf80,MAP2,MARK3,MATN3,MBP,SYT9,POC1B,MRPL42,SAMD5,BLOC1S2,MT3,CTNNA3,MYBPC1,NEXMIF,MYT1,BEX5,NAP1L2,NAP1L3,NEUROD1,NF1,NFE2L2,ALDH1L2,NOVA1,NOVA2,NTRK2,OMG,P2RY1,PCDH9,PCSK2,PDE1C,GPR85,PFKFB2,NOMO2,ANLN,PLCL1,PLIN1,PLP1,PMP2,TRHDE,LRP12,SLC36A4,POU3F2,PKIA,EPDR1,MAPK9,HYDIN,LAMA1,PTAFR,PTCH1,MTMR10,PTHLH,PTN,TMEM260,PTPRB,PTPRD,PTPRZ1,PTX3,PID1,CEP97,USP47,SH3TC2,RASGRF1,VEPH1,ZYG11B,RET,MORC4,RGS7,PBRM1,CARF,ROBO1,ROBO2,CCDC25,PCMTD2,RPE65,FBXW7,GLDN,CNTNAP3,LGR4,ATAT1,AP1AR,SEMA6D,ATXN7,SCN3A,LRRTM4,ASIC4,IL17RB,SUPT20H,HSPA4L,SGK1,ITSN1,PPM1E,DOCK10,HKDC1,R3HDM2,NUBPL,SLA,BTBD3,SLC6A11,SLC11A1,SLC14A1,NAPB,SLC20A2,ATF7IP,SORCS3,FAIM2,MYO16,TRERF1,SOX5,FNBP1,SP2,ZSWIM8,SP4,MYCBP2,KDM4C,TEX2,ZNF423,MCF2L2,NPAS3,ITPRID2,SSTR2,LARP4,LRRC4,ADHFE1,SEPT3,STXBP1,GSE1,KLHL7,SYNE2,SYN1,SYPL1,UNC5D,TBCEL,TMEM136,ANO4,TCF4,SATB2,TCF12,SZT2,DOCK9,RALYL,PCDHB7,FRYL,SIK3,RNF216P1,PMS2CL,DICER1,ITGB3BP,TIAM1,TPM1,NPL,TPM2,SYNPO2,TRPC3,TRPS1,DCBLD1,TSN,ANO5,SSBP2,RFTN2,ZKSCAN5,UBC,EIF4ENIF1,UBE3A,AMOT,GORASP1,PITPNB,PLEKHH2,TBC1D15,P2RY12,LAT2,SF1,ZIC1,ZIC3,ZNF711,ZNF24,ZNF28,CFAP52,FMN2,PLPP4,CELF4,ZNF142,ZNF154,POLR3H,ANKS1B,UPF3A,WNK1,ZXDA,EMSY,STOX2,PRDM8,PRDM10,HPS4,CIAPIN1,SNX27,FAM47E,TRIM16L,SLC17A6,PLSCR4,PARP11,PDSS2,GOPC,DNAH10,FZD3,PAK5,SMIM8,FBXO36,CBLN2" MicroRNA hsa-miR-218:mirSVR_lowEffct hsa-miR-218:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.24E-163 3.51E-159 2.97E-161 2.74E-160 423 1796 "ASIC1,EMILIN3,NCKAP5,SYS1,KLHL32,TMEM132B,ELFN2,ADCY2,ADD2,BRAP,ERMN,PLEKHH1,KIAA1211,RNF150,KIDINS220,DPY19L2P4,KLHL13,KCTD16,CC2D2A,HFM1,LRRC7,SEMA6A,USP35,BCAR3,ABCD2,MARCH4,KCNT1,TRMT9B,AMPD3,KIF6,CDC42BPA,ANK3,PPFIA1,GPAM,DDO,LRRC4C,API5,USP37,SHROOM2,ARHGAP5,LINC00173,CDK13,ATP1A2,ATP1B3,N4BP2L1,DPY19L3,MYOM1,ADAM23,LINC00847,KSR1,BMPR1B,SYNJ1,SYNJ2,ARHGEF7,FUBP1,CACNA1I,CA12,CACNB2,CACNB4,CAMK2B,SPAG9,PRC1,KRIT1,CD86,DGKI,CDH2,CDH10,LOC730101,MAGI1,CFL2,FOXN3,CASC2,SYNPR,LSMEM2,CLCN3,CLCN4,C4orf33,IQCK,BTF3L4,LETMD1,AKAP5,IFFO1,CNRIP1,SH2B1,HAPLN1,CSF1R,MICAL2,OSBPL3,NCAN,SOCS5,VAC14-AS1,PDE4DIP,SLITRK5,KIAA0040,PHF14,USP6NL,CCDC144A,KIAA0408,GAPVD1,DCAF8,FRMPD4,ZFYVE16,RASSF2,TM9SF4,KIAA0586,DGKB,ARMCX4,ZNF804A,ZBTB24,HEPH,HP1BP3,C2CD2L,KLHL3,BLOC1S6,ZC3H11A,SMG7,NTM,USP3,DOCK2,SLC12A6,DPP6,DTNA,DTNB,DNAJB6,E2F5,E2F6,FAM135B,EDNRA,SGK2,SEMA3D,PHF20L1,AASS,SORBS3,EPB41L1,EPHB1,ANKRD13B,STX2,TMEM74,NRN1,CLVS1,ABCA8,CACNG3,TMEM132C,TAOK3,EFEMP1,FCGR3A,STRADA,FDFT1,SEC24B,GTF2IRD2,FGF14,MEX3B,HPCAL4,PCYOX1,FLT1,SGIP1,NOP56,WDR83,SORBS1,HVCN1,USP16,CAMKK2,NSG2,CGREF1,GPR153,CSPG5,TMEM151A,DOT1L,NRG3,HRASLS5,GABRG1,HBS1L,BRPF3,ZNF559,C15orf41,DISC1,PCDH17,GGTA1P,PPARGC1A,KIRREL3,GK,TXNL4A,GLS,TNRC6A,PCDH11X,GNG3,FERMT2,GPD2,GPR12,LPAR4,RAPGEF4,DIDO1,SERP2,GRIN2D,NR3C1,GRM8,RNF165,TMEM25,GUCY1A1,GUCY1B1,MUM1,RASSF8,TOX2,MAN1B1,USP51,HSF2,IDH3A,C5orf24,ZIC5,RBPJ,LRRCC1,SCIN,IL6ST,IL12A,LRRTM3,KCNA6,KCNH2,KCNK2,KCNN2,KCNN3,LAMP2,SYTL4,LOC100128239,MAN2A2,MAOB,SCAMP5,MID1,MOBP,ADAM22,RSPO2,HS6ST3,MYO6,ZC3H12B,NFIA,NFIX,NOVA1,PCBP3,SLC11A2,NRCAM,NRGN,NTRK2,NUCB2,OXTR,GPR137C,CNTN3,PAX6,DPY19L2P2,PDE4B,PDE4D,GPR85,BEST3,OLA1,CDK14,ZDHHC8,DUSP26,GDAP1L1,CCSER2,RETREG1,PURG,LRP12,SCHIP1,FAT3,SH3KBP1,PPARA,PPP3CB,RASGEF1B,PKIA,DIRAS2,QRICH1,CNTLN,BDNF-AS,PXK,PTN,TMEM260,PTPRB,STRC,SH3TC2,RAP1GAP,ZMAT4,RET,RFX2,KLHDC8A,ALG9,RAVER2,CARF,CCDC25,FBXW7,BAALC,GLDN,ABCA11P,ATAT1,DGLUCY,AMER2,SALL1,LRRTM4,FAM19A1,SCP2,SMPD3,SEC14L1,GALNT10,SCAF8,SH3GL3,DOCK10,MAGI3,SLITRK3,RUFY2,SLC8A2,SLC8A3,ELMO2,ATF7IP,SLCO1A2,TET1,ANKRD36,SNCB,MBD5,SNRPN,PALLD,FAM219A,TNIK,KIF21B,BDP1,SOX11,ZSWIM8,NMNAT2,CLUAP1,PEG10,BEX1,SPTAN1,ATP10B,ZC4H2,LRRC4,SS18,ZSCAN29,ELOVL4,NEK4,TTBK2,FGD4,RHBDL3,COBL,ANKRD28,C12orf76,TACC1,ANKRD12,SEMA4A,UNC5D,ALG1,ADGRL3,TBCEL,TMEM136,TBX15,VWA3A,VWC2,TCF4,ZFP90,TPCN2,TRIM2,PHF24,RALYL,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TF,FAM200B,PMS2CL,ZFPM2,C18orf54,ITGB3BP,ZFP91,NR2E1,PARD3,DOK6,NR2C2,SMUG1,TRIO,FNDC5,TSN,TTTY15,TTC3,TUB,TUBB1,UBE3A,SLAIN1,OSBP2,VLDLR,BEST1,VSNL1,RICTOR,ZFP37,ZNF711,ZNF19,ZFP41,GPR158-AS1,FSTL5,PCBP1-AS1,PRDM2,PRTFDC1,SLC38A1,EVI5,STOX2,PRDM8,TMEM178A,MDH1B,PCDH15,LINC00632,ITM2C,WIPF2,C12orf4,PDSS2,RGS7BP,SMIM8,HNRNPA3,ACTR3B,ADAMTSL3,NLRP3,SSPN,NETO1,SOCS4" MicroRNA hsa-miR-367*:mirSVR_lowEffct hsa-miR-367*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.22E-163 4.06E-159 3.41E-161 3.14E-160 415 1730 "TTYH1,AS3MT,EMILIN3,KDM5D,TMCC3,GALNT13,SLC12A5,GRAMD1B,ADORA1,USP31,KIAA1211,SNX30,ADORA3,ADRA1D,BEND6,MTA3,KIAA1324,OSBPL6,AK2,HFM1,ALCAM,ANK3,PKP4,APC,DGKZ,UPRT,DDO,PHYHD1,VAT1L,PPFIA3,DDX3Y,ATP1B3,SLC2A11,DOCK11,SNAI3-AS1,MPDZ,SYNJ2,BSN,LDLRAD4,CA8,CALB2,CAMK2G,MAP7,RUNX1T1,CBR1,CLDN10,LDB2,CBFA2T2,LGI1,CLGN,NUMBL,DIS3L,SRSF11,CHRM1,CASC2,LHX2,COG1,TJP2,QKI,RAB26,ARHGEF6,AKAP7,SUMF2,MYRIP,RBM39,CREB5,CLIP3,SNCAIP,TENM4,RGS6,ATRNL1,SOCS5,PDE4DIP,PHACTR3,UBXN2A,CTH,NRSN1,DCAF4,GPRASP1,ARHGAP32,TBC1D5,LIN54,KIAA0586,KCTD8,PHYHIP,DGKB,SCRN1,AIF1L,ARMCX4,C8orf34,HEPH,RUSC2,SMG7,SV2B,SV2A,SGSM2,G3BP2,TMCC2,DMD,TRAPPC9,NR1D2,CDON,DMTF1,SLC12A6,DPP6,DRP2,RCAN1,DTNA,TOM1,DYRK1A,DNM1L,ABCC9,WDPCP,TMTC1,FRY,RBM12,MBNL2,KMT5B,EGR3,EIF4G2,IRAK4,EPB41,LRRC17,EPHB1,KCNMB2,RABEPK,EPS8,TMEM74,RCSD1,ANKMY1,TLR7,EXTL2,ADGRV1,EYA1,HSPA12B,NSRP1,RPS6KC1,CACNG2,TMEM132C,DLC1,STRADA,SLC9B2,FGF1,OLFM1,FGFR1,SUCO,AGAP2,SYNCRIP,IQCG,SEMA4D,ATP13A4,ANKFY1,FLYWCH1,EFCAB2,ZCCHC17,UFM1,ZNF605,NSG2,NRG3,MPP6,DKK3,MEGF10,GABRA2,GABRA3,GABRB1,GABRB3,BRPF3,ZMYND11,ERAP1,DISC1,CYP46A1,GFER,GFRA2,PCDH17,CRCP,RAB30,TOX3,GNAL,GPR12,GPR19,NUDT21,RAPGEF4,GRB10,GRIA2,GRIK1,ADAMTS13,NR3C1,GRM7,CIT,LINC00839,TMEM25,AP4S1,RNFT2,PTGDR2,HMGB1,HPSE2,C9orf129,NEGR1,HTR2A,C2orf72,RBPJ,KNDC1,KIAA1755,LIX1,SLC6A17,KCNA6,KCNC1,KCND1,KCNK1,KCNMA1,KCNN3,KIF5C,STXBP5,TTYH2,INSYN2,LIMS1,PAXBP1,MAP2,MAP6,MARK1,MAT2A,MBNL1,MBP,SYT9,EFHB,LRP1B,MEIS1,MIA2,XRRA1,ZNF680,PTOV1,CTNNA3,MYO7A,MYO9A,CNOT4,NOVA1,PCBP3,SNTG1,PCDH9,PCSK1,CDK18,PDE3B,PFKFB4,NLGN3,GDAP1L1,SERPINI1,SEMA5B,ZNF655,SNX10,PLCB2,PLCL1,HMGCLL1,PLXNB3,ANKRD16,PMP2,ING3,SLC36A4,POU3F2,POU6F1,CCDC144B,PPP2R5C,MAPK4,MAPK8,MASP1,SYTL2,LAMA1,SIDT1,PTAFR,PTHLH,PTPRE,CASTOR1,PTPRG,PTPRO,RAD17,ZCWPW1,RASGRF2,DBX2,MSANTD2,RET,RGS4,RGS12,SEC61A2,RPRD1A,LGI2,GSTCD,ROBO2,MRAP2,ARMH4,UEVLD,MCMBP,LRRK2,ABCA11P,WLS,YJEFN3,STX1B,S100B,SCN2B,LRRTM4,LINC00461,PRCD,FNIP1,IL17RB,FOXRED1,ASRGL1,SUPT20H,TRA2B,ITSN1,ARX,NTNG1,CHD9,ANKRD6,ZNF365,SLC1A6,SLC1A7,PPP4R3A,RUFY2,RADIL,SLC11A1,ZNF334,SLC14A1,ELMO2,TET1,ZNF667,ANKRD36,SNAP25,MBD5,KIF13A,SNRPN,KDM4B,PDZD2,SP4,GLT8D1,PEG10,ZC3H13,KIF1B,NPAS3,NFASC,TAB2,PBLD,SSTR1,ZC4H2,SSPO,MAPK8IP3,ZSCAN29,ELOVL4,ADHFE1,SULF2,ZFR2,VAMP1,ARHGEF9,SLC37A2,C12orf76,POPDC3,WWC1,TBCEL,IQCE,FBXW11,SMG6,ANO4,VWA3A,VWC2,SIN3B,ZFP90,TCF7L2,TPCN2,TCF12,DOCK9,SLC19A3,RNF175,TEX15,FAM200B,PMS2CL,SIRT1,RELL2,DDHD1,TNFRSF1B,TNR,PIK3R5,C9orf85,NEIL2,STXBP4,TRPC1,UBE3A,FRRS1L,FLRT2,BCL2L13,CCDC14,RBFOX3,ZNF24,TRIM9,AGMO,MKRN3,ANKS1B,ZNF213,PRDM2,SLC38A1,LINC02210,HPS4,CIAPIN1,URM1,MPPE1,SLC17A6,C12orf4,PDSS2,RGS7BP,FAM13C,SMIM8,CASC15,NUP214,TRAM2-AS1,NHSL1,KLHDC1,CBLN2,ST8SIA2,LAS1L" MicroRNA hsa-miR-10a*:mirSVR_lowEffct hsa-miR-10a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.26E-163 5.20E-159 4.34E-161 3.99E-160 418 1756 "KDM5D,CSMD3,ADD3,CDC7,USP31,PTCHD1,ADRB2,INTS2,PCDH19,ALCAM,PCDH10,FAM135A,LRCH2,MAP4K3,ANXA7,PARG,APAF1,MAGEE2,CACHD1,APP,MIER1,PPP4R4,TMEFF1,ARNTL,RGS20,ASCL1,STK33,ASPH,NCOA1,DDX3Y,CCDC181,EIF4G3,B3GALT2,DPY19L3,BACH1,SEC11C,DCAF5,CDK5R1,SYNJ1,NAE1,BTK,WASF1,KALRN,VSTM2A,CAST,MAP7,ZNF501,LDB2,USP2,TMEM257,CDH2,CDH18,L3MBTL4,MAGI1,CCPG1,CLGN,SRSF11,SOCS6,KMT2C,NRXN3,CLCN4,FADS2,ABCG2,QKI,NIPBL,CNTFR,ARMC8,AKAP6,COL4A5,COL9A3,RCHY1,GAL3ST1,ZNF521,ZFP28,ANKRD44,FEZ1,ARHGEF10,ATRNL1,VCAN,PHACTR3,DZIP3,APPL1,PNPLA8,CFAP61,RIMS2,ZSCAN23,RUBCN,HDAC9,FGFR1OP2,KIF26A,TMEM170A,PITPNC1,ARMCX2,ELMO1,C2CD2L,CEP170,MAGI2,DDX46,OLIG1,DYNC1I1,DTNA,DYRK1A,DNM1L,AASDH,WDPCP,FAM135B,ATL1,FSD1L,RBM12,PHF20L1,APH1A,EGFR,EIF4G2,TMEM35A,STARD3NL,EPHA5,DENND4A,ETV1,ADGRV1,ARMCX1,ABCA8,TAOK3,CEP78,FDFT1,FER,MED12L,GTF2IRD2,SUCO,SCARA3,EFCAB2,TACC2,APOPT1,KHDRBS3,ST6GALNAC3,STAU2,DOT1L,MPP6,GALNT15,GABRG2,ILDR2,AHCYL1,FAM120B,GALR1,ZNF234,IQGAP2,MTHFD2,C15orf41,MYOZ2,GATM,MSTN,ADAM28,MMADHC,GGT7,GLRB,TNRC6A,STARD3,ZNF638,KDM2B,RAB40B,GNAO1,WDFY3-AS2,GPM6B,STON1,GPER1,CECR2,GRIA4,FAM19A2,ZBTB49,PSIP1,ADAMTS6,GUCY1B1,MAP4K5,WIF1,IRAK3,HPS5,NXPH2,FRMD5,CELF5,C5orf24,DOCK7,LRRCC1,USP54,SCIN,RIPPLY2,TUBB2B,LRRTM3,LRRTM1,SLC35G1,KCNC2,KCNK2,IPO5,LAMP2,PAXBP1,LMO1,ARHGAP12,LOC100128239,MAP4,MAT2A,MBD1,MBNL1,SYT9,TM6SF1,LRP1B,KITLG,POC1B,AFDN,ZNF680,ADAM22,MSRA,CTNNA3,MTTP,MYT1,HNRNPM,NAP1L2,NCAM2,NEK1,NELL2,NEUROD1,NEUROD2,NF1,SLCO1C1,NFIA,NKX2-2,NOVA1,DNHD1,NRCAM,SMIM11A,HCN1,OLR1,P2RY1,SNTG1,PAK3,CNTN3,PAX6,PBX1,PCSK1,PDE4B,PDGFRA,ABCB1,CCSER2,SNX10,KCTD15,GPSM2,PURG,MAPKAP1,PSAT1,SCHIP1,EPB41L4B,NXPH1,CRLS1,PPP2R5C,PPP3CB,KANSL1,RANBP3L,PKIA,RAB39A,KLK6,CNNM2,SIDT1,SNRK,PTCH1,PLPPR1,PTHLH,ZSCAN32,PTPN13,OCIAD1,PTPRD,PTPRN2,PTPRZ1,TTC13,CEP97,RAD17,FAT4,RAP1GDS1,ZCWPW1,ARID4A,RBBP6,KHDRBS2,SLC6A15,REV3L,GTDC1,RFX3,RLBP1,SLC25A36,PBRM1,ZFHX4,RERGL,CARF,RORB,UEVLD,ADAL,ACER3,CNTNAP3,LGR4,WLS,ZNF354C,ZNF568,NCBP3,SAFB,ATXN7,ELMOD1,SFPQ,SCAF8,ZFP30,KIF21A,SH3GL3,KIF16B,MAGI3,FBXO11,FNDC3A,NLGN1,WDR37,SLC6A1,CCDC88A,BTBD7,CPEB4,SMARCE1,SNAP25,CMTR2,ZNF415,SNRPN,SON,MYT1L,TNIK,KDM3A,ENKUR,ZC3H13,MCF2L2,RBM26,SPART,C11orf87,CLASP2,MESP1,STOX1,SAMSN1,EPB41L3,LRRC4,SS18,STAU1,NEK4,KLHL7,NECAB1,PRRC2C,VPS13A,PLCB1,TACC1,PJA1,MCF2L,CAMSAP2,KIAA1107,FBXW11,ANO4,VWA3A,TCEA1,SATB2,DOCK9,TNS2,PCDHA5,RNF175,SIK3,DNAH7,SIRT1,ZFPM2,ITGB3BP,TGFBR3,HHIP,AKTIP,CSMD1,PIK3R5,ZNF384,PRMT8,TRIO,TTC3,PRR18,CLHC1,HIRA,RPRM,UBE2H,UGT8,DNAJC12,SLAIN1,USP1,TOM1L2,VSNL1,WIPF1,GUSBP1,XPO1,ZIC3,ZNF711,TRIM9,FMN2,CELF4,EML6,ANKS1B,MFF,CADM2,PRTFDC1,SLC38A1,LINC02210,RNF103,ADAMTS9,MDH1B,FIP1L1,TMEM163,WNK3,SLC17A6,PDSS2,DNAH10,FAM13C,FZD3,UBE3B,PHTF2,CASC15,TIGD6,SLC39A12,SSPN,IFT88,SOCS4" MicroRNA hsa-miR-222*:mirSVR_lowEffct hsa-miR-222*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-162 6.78E-159 5.60E-161 5.16E-160 404 1642 "NBAT1,ACTN1,KDM5D,KLHL32,SORCS1,GPR158,PCDH19,TXNDC16,CC2D2A,GOLGA7B,FAM135A,ZFAT,LCORL,PHF12,PPFIA1,APC,LRRC4C,USP37,ZFYVE28,ARNTL,RGS20,ZBTB10,ATM,ATP2A2,ATP2B1,B3GALT2,TTLL9,BACH1,KSR1,SYNJ1,SYNJ2,ARHGEF7,LINC00906,RAB29,CA8,CACNA1E,CACNB4,CANX,SPAG9,SHISA7,USP6,SCARB1,DGKI,CDH2,LGI1,MAGI1,CDO1,TIGD7,NOG,CHM,CHN1,CASC2,KMT2C,NRXN3,PPT2,COG1,TPP1,QKI,NIPBL,AKAP5,SLC4A7,MAGED1,CNRIP1,CHD1L,CREM,RBM39,TRIM69,SOCS5,VAC14-AS1,PDE4DIP,PPP1R16B,APPL1,RIMS2,USP6NL,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP24,ZFYVE16,ZNF337,MATR3,DBI,PITPNC1,DNAJC6,ZEB2,FBXL5,KLHL3,FBXO25,SPOCK3,AK5,WDR20,RAB39B,NR1D2,SLC12A6,FAM57B,DSCAM,GNE,ARRDC4,DTNA,DYRK1A,DNM1L,EDNRB,ATL1,SGK2,FCF1,RASGRP1,KLHL5,SH3GLB1,GPR61,PHF20L1,C8orf37,CALCRL,DCTN4,LRRC17,EPHA5,GPHN,SPEG,TMEM74,ABCA8,CHST15,TOMM40L,SLC9B2,FGF1,FGF13,FHL1,POLK,UBE2E3,MEX3B,FOXF2,PCYOX1,SYNCRIP,EVL,FLT1,PSD2,TACC2,HVCN1,UFM1,TPK1,CAMKK2,ATP2C1,DACH2,NSG1,DLL3,KBTBD12,B3GAT1,HHIPL1,ZMAT1,GALNT15,GAD2,HBS1L,ATP8A2,GGT7,PPARGC1A,MALT1,LYVE1,TXNL4A,GLRB,STARD3,MAP7D2,WDFY3-AS2,ADGRA3,GPM6B,EML4,GPR37,PCLO,TPPP,GRIA4,NR3C1,GRM1,GRM3,COQ10A,GSTM5,BVES,AP4S1,PSIP1,RNFT2,FAM222A,HPS5,ZHX1,FRMD5,ARHGAP36,C9orf129,CPT1C,TCEAL6,DHX35,LRRC75A,IGF1,RBPJ,IGSF1,SCIN,IL6ST,IL11RA,BRINP3,KCND2,KCNJ3,KCNJ10,KIF5C,IPO5,LAMP2,PAXBP1,HECTD2,ARHGAP12,MARK1,MARK3,MBNL1,MBP,LRP1B,AFDN,SESN3,CCDC80,MSI1,NF1,SLCO1C1,NFIA,NFE2L2,NFYA,NNAT,NPTX1,NTRK3,SETD4,OPCML,PDE1C,PDE3B,PDE4B,BEST3,PFKFB3,NALCN,CAMKV,PIK3C2A,PIK3R1,CCSER2,RETREG1,XRN1,PKM,PLIN1,PLP1,PRIMPOL,SCHIP1,EPB41L4B,PPP2R2B,PPP3CA,PPP3CB,PRKCB,HYDIN,DIRAS2,DCHS2,MASP1,RELN,MTMR10,PTHLH,PTN,ZSCAN32,TTC13,TUG1,PPP2R3C,TMEM255A,FAT4,ZNF493,RASGRF2,ARID4A,RDX,ZYG11B,ZMAT4,RIC8B,NUDT11,RPRD1A,LGI2,CARF,ROBO1,RORB,BAALC,RTN1,RYR3,CCDC112,RMI1,AMER2,SATB1,LRFN5,SCN3A,SCN8A,ELMOD1,PEAR1,SEC14L1,SOX6,HSPA4L,SH3GL2,CPEB3,NTNG1,SHC4,MAGI3,CHD9,CCDC92,FAM81A,PEX26,DHX30,ZNF430,RAB3GAP1,SLC20A2,SPHKAP,CPEB4,SMARCE1,ANKRD36,INAVA,RIMS1,SNCB,MYO16,KDM4B,DOP1A,BDP1,DOK5,KDM3A,GLT8D1,MYCBP2,ZBTB43,TSPYL2,RBM26,NPAS3,C11orf87,SRPK2,PBLD,THSD1,SMOC1,EPB41L3,ZC4H2,STAU1,CEP68,RGL1,SULF2,KLHL7,ARHGEF9,PLCB1,SYN2,TAC1,PJA1,TAF9,UNC5D,ANO4,EHBP1,DMXL2,ZFP90,ZEB1,PCDHB7,PCDHB3,ARHGEF12,USP32P1,GPRIN3,CRB1,GPR161,ZMAT3,AKTIP,SLC44A1,TJP1,TLR4,HEY2,TMOD1,TMPO,FAM124A,RIMBP2,CDK20,TPM3,C9orf85,RGMB,STXBP4,ANO5,TTC3,ZKSCAN5,RPL7L1,UBE2H,UGT8,PITPNB,USP1,BCL2L13,VLDLR,VSNL1,WIPF1,WRN,CLDND1,PCDH20,ZNF711,SLC26A10,MKRN3,ZNF138,PCBP1-AS1,SPIRE1,CA10,PRDM2,CSDE1,PRDM8,RNF103,SCG2,HPS4,PCDH15,FIP1L1,FAM47E,PCBP4,SLC17A6,PDSS2,HRASLS,RGS7BP,RTN4,JMJD1C,SOCS4,CPNE4" MicroRNA hsa-miR-1303:mirSVR_lowEffct hsa-miR-1303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-162 8.27E-159 6.78E-161 6.24E-160 430 1859 "CLK4,TMEM132B,GALNT16,SLITRK1,ADD2,PLEKHH1,GRAMD1B,MTA3,KLHL13,PCDH19,RTL9,HACE1,KIAA1324,ZNF578,LRRC7,ALCAM,PCDH10,UNC79,GPRASP2,ZFAT,EP400,LCORL,PPFIA1,ANXA7,APBA2,KCNAB2,EPB41L5,GAS7,DDO,TNRC6C,PPFIA3,USP37,APP,LGR5,IGDCC4,CASK,ASPA,MARK4,ASPH,PCDHGB4,NUMB,ATP2B1,SLC2A11,MTMR9,ATP6V1G2,RIPK1,ADAM23,ADGRB2,ADGRB3,BBS2,BLM,ARHGEF7,GYG2,SGCE,C5,BSN,CACNB4,CAMK2D,SLC25A14,VSTM2A,SPAG9,MAP7,RUNX1T1,METTL6,CCNH,P2RX6,SEPT7,DCLK1,SYNPR,EPS15L1,NRXN3,KIAA1549L,NIPBL,TMEM155,IQCK,ARMC8,AKAP6,LETMD1,SLC4A8,ABI3BP,AHCTF1,CPS1,HAPLN1,ANKRD44,ARHGEF10,SUSD5,SOCS5,PDE4DIP,CNTNAP2,APPL1,PHF14,GPSM1,DCAF4,CYBB,FRMPD4,ZFYVE16,EARS2,LONRF1,DGKG,SCRN1,DNAL1,PITPNC1,ELMSAN1,ZEB2,KIAA0319,FBXO25,PLPPR4,WDR20,ARNT2,SEC16A,DLG3,DLX1,SLC12A6,DNAJB6,DYRK1A,ABCC5,ABCC9,WDPCP,EDN1,CNNM1,SEMA3D,KLHL5,TMTC1,EFNA3,SH3GLB1,APH1A,EGFR,MRO,KMT5B,ASB3,PLEKHA1,ELN,C3orf18,EMX2,OLIG2,EPB41,EPB41L1,GPHN,SRRM1,DENND4A,CEP85L,SPEG,EXTL2,KATNAL1,ADGRV1,EYA1,HSPA12B,NSRP1,FAM198B,CACNG3,ACSL4,TAOK3,CEP78,FKTN,SYNCRIP,RGPD5,FOXM1,EVL,SORBS1,PDLIM5,RASL10A,NPTN,CAMKK2,ZNF605,ERGIC3,DACH2,GPR153,MPP6,FYB1,FYN,GABRA1,GABRA3,GALNT15,GALC,GALR1,GBX2,SULT1C4,MMADHC,USP19,TTBK1,GLDC,GLI2,PCDH11X,WDFY3-AS2,PRUNE2,LILRA1,GPER1,GPR34,TMEM121B,GRIK2,NR3C1,GRM8,LINC00839,RABL2A,GUCY1B1,ATG4C,HAS2,PADI2,VSIG4,HMGCR,NEGR1,HSP90AA1,SMAP1,ATCAY,NKD1,PLD5,IBA57,INPP5B,INSM1,KCNA1,GPR62,KCNJ9,KIF5A,KLRC3,KLC1,IPO5,CYP27C1,LAMP2,SYTL4,HECTD2,MAG,MAN2A2,CHST6,CHIC1,TM6SF1,MEIS1,KITLG,AFDN,MMP16,CD200,ERICH3,ZNF680,SAMD5,SESN3,SCG3,ZC3H12B,NF1,DNHD1,LRIT2,NRCAM,NTRK2,OPA1,OPCML,OPHN1,PAK3,PBX1,ETFRF1,PCDHGC3,PCSK2,PFKFB2,GDAP1L1,PIK3R1,CCSER2,XRN1,FTO,PLP1,MTRF1L,PDZRN4,TRHDE,LRP12,ING3,DRAM2,PPM1B,PPP2R5C,KANSL1,PPP5C,RANBP3L,RASGEF1B,SLC22A23,GON4L,PSMD13,UHRF1BP1,PTHLH,PXK,TMEM260,PTPRD,CASTOR1,FAM120C,PYGM,NKAIN1,RAD17,FAM66C,FAT4,NWD1,ZNF493,ARID4A,FEZF2,RBBP8,RADX,BSDC1,SLC6A15,ZYG11B,TRIM68,RFX5,PRIMA1,RPRD1A,CCDC82,SETD5,TMLHE,EXD2,CYB561D1,ATP8B4,SGSM1,MAP6D1,ABCA11P,ATAT1,FAM192A,SEMA6D,ATXN1,ELMOD1,SEC14L1,SOX6,SUPT20H,CPEB3,DOCK10,FNDC3A,WDR37,SLC1A3,RPH3A,EPN2,SLC6A1,SEPHS1,SIRT2,TRIM67,SLC11A1,SHANK2,KBTBD4,ELMO2,BTBD7,SLC22A4,ABTB1,SORCS3,ANKRD36,LIMCH1,RIMS1,KIF13A,SNRPN,FAM126B,KDM4B,SCN3B,KIF21B,ZHX3,ENKUR,ERC1,ZNF423,KIF1B,CDK19,RBM26,RAP1GAP2,LARP4,FCHO1,SULF2,SEPT3,SYT11,FGD4,NUDT10,ADAMTS17,C3orf70,TMEM150C,ANKRD28,ASTN2,DNMBP,ADGRL3,ACSL6,TCF4,KIAA0930,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,FAM189A1,NSD1,PUM2,CRB1,AKTIP,GZF1,TLL2,BHLHB9,ERCC6L2,KAT6B,DOK6,ZNF384,RGMB,AMACR,STXBP4,TRPC3,TTTY15,TTPA,PRR18,TUBB2A,HIRA,DNAJC12,FLRT2,FLRT1,BCL2L13,MTCH1,MEAF6,P2RY12,RICTOR,XRCC4,ZNF24,TRIM9,CELF4,SLC38A1,TUBA1A,FAM47E,SLC17A6,MVB12B,PLSCR4,PDSS2,GOPC,FZD3,UBE3B,FBXO36,NUP214,CERS6,RNF170,KLHDC1,CPNE4,LAS1L" MicroRNA hsa-miR-875-3p:mirSVR_highEffct hsa-miR-875-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.79E-162 2.69E-158 2.19E-160 2.02E-159 427 1839 "KCNH8,ACADM,CLK4,ACTN2,XKR4,ADAR,KLRC4,SLITRK1,ADCY6,CCDC85A,ADD1,SORCS1,ERMN,ADORA2A,KIDINS220,NLGN4X,AP2A2,MTUS1,GPR158,HACE1,TBC1D14,WDR35,TXNDC16,LRRC7,SPARCL1,SEMA6A,SPOP,MARCH4,OGT,DPP10,ANK2,PHF12,PKP4,PARG,APBA2,UPRT,GPAM,VAT1L,BCAS1,LGR5,MIER1,IGDCC4,MARCH3,CAPRIN2,NCOA1,STX16,ATP2B1,RNF182,DPY19L3,RGS9,NRP2,GPR146,ARHGEF7,NAE1,LINC00906,BTK,NIPA1,IL33,BTRC,CA8,KALRN,SLC25A14,CAST,ISPD,SPAG9,MAP7,RUNX1T1,CBR1,MTMR7,ZMYM4,LRRFIP1,NUMBL,CFL2,CHN1,SYNPR,NDST3,TPP1,STOML1,CLTA,C4orf33,TMEM184B,HECTD1,NIPBL,ARMC8,AKAP6,SLC4A8,RCHY1,MYRIP,IGDCC3,CNRIP1,SLC35F1,CRMP1,GDA,SNCAIP,MICAL2,CSNK1G3,VCAN,CNTNAP2,FAM169A,PHF14,PNPLA8,CTH,CTNND2,PUM1,ZSCAN23,CYBB,ARHGAP24,FRMPD4,ZNF337,DGKB,DAPK1,GIT2,SPATA2,DNAJC6,ZEB2,ELMO1,CEP170,G3BP2,RABGAP1L,DLG2,GRIN3A,USP3,DRD1,DNM1L,ABCC9,AASDH,USH1C,EDNRB,SGK2,HIPK3,CNNM1,SEMA3D,YAF2,APH1A,MRO,MBNL2,ABI2,GOLGA7,KCTD3,SORBS3,TMEM35A,RCAN2,DMTN,RASGRP2,EPHB1,ENPP6,STX2,SRRM1,NCALD,MRPL37,TMEM74,RCSD1,ZNF461,FABP7,SH3YL1,TAOK3,EFEMP1,TOMM40L,SEC24B,FGF12,SCARA3,IP6K2,SYNCRIP,ATP13A4,SGIP1,NBEA,SPECC1,ZNF605,KHDRBS3,FYN,HRASLS5,GABRB1,GABRB3,GABRG2,CAB39,GAD1,HBS1L,GALC,RAPGEF6,ARPP21,TMEM8B,MTHFD2,DISC1,WASF3,LRRC37A6P,NEU3,GCNT2,SRCAP,MSTN,CRCP,COPS8,SPIN1,RAB30,GLS,CBX1,GNAS,GPD1,GPM6B,GPR12,RAPGEF4,GRIK1,GRM7,KIF3A,AP4S1,PSIP1,IRAK3,IGSF21,FRMD5,ELOVL5,HSPA1L,HTR2A,IRF8,C5orf24,IL6R,IL6ST,LRRTM3,ITGAM,KCND2,KCNK2,STXBP5,SYTL4,NCOA7,LSS,PIK3AP1,MARK3,MAT2A,PPM1L,XRRA1,MMP16,ERICH3,MRPL42,MSI1,CTNNA3,MYO7A,FXYD6,NAP1L3,NCAM1,NEUROD1,NF1,NOVA1,NUCB2,IGSF11,GPR88,OPA1,P2RY1,GPR137C,PCSK5,PCSK2,PDE4D,GNG2,PFKFB2,SERPINI1,ANLN,A2ML1,SNX10,PLP1,SMIM7,TRHDE,MAPKAP1,EXOSC10,ING3,MBOAT7,FAT3,NXPH1,POU3F2,CRLS1,PPP2R5E,PPP3CB,RANBP3L,CEP41,GRAMD1C,HYDIN,GDPD1,VPS13C,MDGA2,CNTLN,SPDL1,ZIK1,PTPRD,C1orf109,ZSCAN2,ACSS3,FAM66C,VEPH1,GTDC1,RFX3,SEC61A2,SLC25A36,NUDT11,EXD2,CARF,GSTCD,ELP2,RPE,NEK11,RPL15,ATP8B4,ACER3,RPS6KA2,MAP6D1,KCNIP1,CLIP1,ZNF568,TRAPPC13,AMER2,SEMA6D,ATXN7,SCN2B,PRCD,SCP2,TNFRSF19,MRAS,KIF27,SH3BGR,KIF21A,PPM1E,NTNG1,MAGI3,NLGN1,ANKRD6,NUBPL,PAAF1,ZNF365,FAM81A,SLC2A5,RUFY2,LRRC55,SEPHS1,SLC8A3,CCDC88A,SLC11A1,SLC15A2,CPEB4,NAXD,ZNF667,GKAP1,SORCS3,CDK5RAP2,SMARCD3,LIMCH1,SNAP25,KIF13A,LMBRD1,KDM4B,FAM219A,SOX5,BDP1,FNBP1,KDM4C,LMO3,C11orf87,TAB2,CLASP2,NKAIN2,ERBIN,INKA2,STAU1,ELOVL4,CEP68,RGL1,DIP2A,AJAP1,KLHL7,PRRC2C,DNAJC9,SYN2,SYT1,COBL,ADGRL3,DMXL2,TCF7,TPCN2,WDR7,SYNE1,RALYL,FRYL,TEX15,PMS2CL,DICER1,C18orf54,GPR161,ZMAT3,TGFBR3,HHIP,GZF1,TIAM1,DDHD1,ERCC6L2,TMOD1,TMPO,PRMT8,TRPC1,ZMYND8,RFTN2,ZKSCAN5,SGK3,UBE3A,AMOT,GORASP1,UGT8,OSBP2,USP1,CCDC14,P2RY12,NSD2,CFAP298,ZBTB14,ZIC1,ZNF74,NDRG4,ZFAND5,SMARCAD1,DHX33,SLC30A4,EMSY,DNALI1,SLC38A1,RNF103,ADAMTS9,PCDH15,MPPE1,EPM2A,KAT6A,PHTF2,CASC15,FXR1,GAN" MicroRNA hsa-miR-548k:mirSVR_highEffct hsa-miR-548k:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.03E-162 2.83E-158 2.28E-160 2.10E-159 409 1689 "CPNE2,RALGAPA1,RBM10,FMNL2,ADCY2,TMCC3,SLC12A5,PWWP2A,OLMALINC,ZNF608,KLHL13,OSBPL8,CC2D2A,HFM1,TAOK1,LRRC7,ALCAM,ABCD2,MARCH4,AMPD3,AMPH,OGT,LRCH2,MAP4K3,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,PARG,ALS2,VAT1L,API5,MIER1,PPP4R4,CDK13,ASPH,ZBTB10,CCDC181,ATP1B3,ZNF583,NOL4,DOCK11,ADGRB3,BBS2,MPDZ,SEC11C,DCAF5,BMP7,CDK5R1,ARHGEF7,FUBP1,SCAPER,C5,WASF1,CACNA1B,KALRN,METTL6,TMEM257,C1orf52,LRRFIP1,CDH18,LGI1,L3MBTL4,CFL2,RCBTB2,CHN1,B4GALT6,JAM2,LHX2,NRXN1,TJP2,QKI,CNN3,CNTN1,ARMC8,COL4A5,SLC25A27,COL9A1,SLC4A7,SLC4A8,ABI3BP,IFFO1,AHCTF1,CP,CRHBP,ANKRD44,GDA,TENM4,FEZ2,CSNK1E,CSNK1G3,SIPA1L1,VCAN,ERC2,CTNND1,ZSCAN23,RIPOR2,ARHGAP24,HDAC4,LIN54,MATR3,PABPC5,GIT2,PITPNC1,YTHDC1,ZEB2,KIAA0753,COPS7A,ZC3H11A,DDX46,PLPPR4,SACS,SV2B,G3BP2,DLG2,DYNC1I1,DOCK2,DPYSL2,SLC25A18,PDCD6IP,ABCC5,GOLT1B,WDPCP,EDN1,EDNRB,ANKRD46,RASGRP1,SEMA3D,FSD1L,MBNL2,KMT5B,AASS,COPS4,TENM1,ELAVL2,ELAVL3,C8orf37,PAN3,DCTN4,COQ7,KCNMB2,CEP85L,ZNF549,RTN3,EXTL2,F3,ABCA8,ACSL4,SCML2,CEP78,CHST15,FCGR3A,KAT8,GTF2IRD2,FGF13,POLK,MEX3B,ATP13A4,FLT1,JKAMP,NBEA,USP16,CSPG5,MSANTD4,ZMAT1,GABRA2,TRAF3IP2,RAPGEF6,ARPP21,GALR1,NEK6,NCKAP1,ERAP1,C15orf41,KIAA1841,IGSF5,SESN1,ADAM28,CRCP,RNPS1,TNRC6A,ZNF638,LUZP2,RAB40B,WDFY3-AS2,ADGRA3,GPD2,PRUNE2,GPM6A,GPR12,TUBA1C,GRIA2,GRIA4,GRM7,FAM19A2,COQ10A,BVES,AP4S1,PSIP1,ADAMTS6,MAP4K5,MAEL,MIER3,HSF2,CELF5,EID2B,C5orf24,NKD1,RBPJ,JAK2,METTL21A,KCNK2,IPO5,INSYN2,LIMS1,FGFBP3,ARHGAP12,NCOA7,SMAD1,MARK1,MBD1,MBNL1,SYT9,MEF2C,SRSF12,MIA2,KITLG,POC1B,MOG,CD200,ZNF680,MRPL42,THYN1,ZNF92,FXYD6,NFE2L2,NOVA1,SLC11A2,NRCAM,P2RY1,GPR137C,DPY19L2P2,PDE3B,PDE4B,CYTL1,CDK14,FAM218A,CCSER2,ZFYVE21,RETREG1,PLCB2,PDZRN4,STRN3,LRP12,EXOSC10,NXPH1,LRRN3,PPP2R5C,PPP3CA,PPP3CB,PRKACB,PRKCB,PROX1,MASP1,MDGA2,CNTLN,SPDL1,FAM120C,PTPRZ1,PPP2R3C,PLEKHB2,ZNF793,ZNF493,ARID4A,RADX,SLC6A15,ERI2,RFX4,RGS3,SLC25A36,PBRM1,RPRD1A,DCUN1D2,ALG9,CARF,GSTCD,ROBO1,RORB,MRAP2,RPE,TMEM100,LRRK2,MEG3,HUNK,SOX8,RTN1,CCDC112,AP1AR,SEMA6D,SATB1,ATXN7,SEC14L1,FOXRED1,PPP1R9A,ARX,MAGI3,CHD9,PAAF1,ZNF365,WDR47,FAM214B,LRRC55,SEPHS1,CCDC88A,KBTBD4,NAPB,CPEB4,SMARCE1,RCOR3,RIMS1,SNAP25,PALLD,PDZRN3,PDZD2,MYT1L,SP2,SP4,UHRF1BP1L,KDM4C,CDK19,ZBTB43,RBM26,NPAS3,C11orf87,SRPK2,TAB2,CLASP2,ITPRID2,SS18,CEP68,TTBK2,ZC3H4,VPS13A,SYT4,MTCL1,CAMTA1,CAMSAP2,FAM208A,ADGRL3,AGTPBP1,TCEA1,VWC2,DMXL2,SATB2,ZFP90,ZEB1,CLASP1,DOCK9,PCDHB9,PCDHB7,PUM2,FRYL,ZFPM2,CRB1,ITGB3BP,AKTIP,ARL10,TIAM1,ASXL3,NR2E1,TMPO,CSMD1,RUNDC3B,TRPS1,TSC1,FAM155A,BCL2L13,XRCC4,SF1,PCDH20,ZFP37,ZIC1,ZNF711,ZNF708,MICU3,ZNF45,GPR158-AS1,CELF4,ZNF142,ZNF189,PLPPR5,EMSY,RNF103,NAV2,WNK3,DNAH10,FAM13C,PAK5,KAT6A,HNRNPA3,PHTF2,ACTR3B,FAM219B,ADAMTSL3,JMJD1C,KLHDC1,IFT88,CBLN2,CPNE4" MicroRNA hsa-miR-616:mirSVR_lowEffct hsa-miR-616:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-161 6.61E-158 5.29E-160 4.87E-159 417 1759 "ABAT,CLK4,SYS1,KDM5D,KLHL32,TMEM132B,CCDC85A,GALNT13,BRAP,SORCS1,ERMN,PTCHD1,BEND6,AP2A2,HECW2,HACE1,NME5,TAOK1,SPARCL1,SEMA6A,SPOP,ALCAM,CEP126,PCDH10,FAM135A,GPRASP2,ANK1,LRCH2,ANK3,MAP4K3,ANXA7,CNTNAP1,GPAM,LRRC4C,LGR5,SLC7A14,CDK10,PDE8B,CAPRIN2,ASPH,RASL11B,ATM,ATP1A2,ATP2B1,N4BP2L1,RGS11,GPR146,FUBP1,SCAPER,SGCE,CACNA1G,GPC2,RAB29,WASF1,IL33,CA12,CACNB4,PTBP2,CAMK2G,MAP7,RGN,CBFA2T2,CD38,CDC42,CDH2,L3MBTL4,DLGAP1,TIGD7,NOG,CHN2,PPT2,KIAA1549L,DGCR9,CLTC,ABCG2,DNAJB5,HECTD1,MAP4K4,AKAP6,COL4A5,SLC25A27,COL9A1,COL9A2,SLC4A7,RCHY1,COX4I1,CP,NECTIN3,CREM,RBM39,GDA,TRIM69,TENM4,CSF1R,FEZ2,OSBPL3,ATRNL1,VCAN,PHACTR3,PLXNA4,SLITRK5,DZIP3,SDC3,PLCXD3,SLC45A1,PUM1,CX3CR1,KIAA0408,BOC,EARS2,KCTD8,TOMM20,PABPC5,GIT2,DNAL1,ARMCX4,ELMSAN1,DNAJC6,JAKMIP2,ZEB2,MFAP3L,FBXO25,LYPD1,DDX46,AK5,RABGAP1L,EXOG,GRIN3A,DMD,CASP8AP2,DRD1,ACOT8,ATN1,PDCD6IP,MAMLD1,ABCC9,SNX29,EDN1,EDNRA,SGK2,HIPK3,SUGP2,EGFR,MBNL2,KMT5B,ABI2,TENM1,ELN,TUBD1,SEZ6,CEP85L,DNAJC27,ADGRV1,ARMCX1,RPS6KC1,TBC1D16,FCGR1A,KAT8,ZNF589,FER,KIAA1109,OLFM1,POLR1B,FGF12,FGF14,FGR,PRKAG2,FHL1,POLK,IP6K2,FOXO3,SEMA4D,PSD2,SGIP1,EFCAB2,TPK1,ATP2C1,DACH2,MSANTD4,MPP6,PHYHIPL,GABRA1,GABRB3,GABRG1,GABRG2,RAPGEF6,GALR1,IQGAP2,DISC1,CPLX2,IGSF5,NEU3,GCK,GPR162,CYP46A1,ADAM28,PCDH17,TTBK1,COPS8,HPGDS,GLI2,GLYR1,GLS,PCDH11X,MAP7D2,FERMT2,PRLHR,NUDT21,RAPGEF4,ATP2B1-AS1,GRB10,GRID1,GRM1,PRDM5,GRM8,CIT,MFSD2A,GUCY1B1,ATOH8,WIF1,NXPH2,PTGDR2,NCKAP1L,HSF2,HTR5A,LINC00667,C2orf72,GAREM2,DOCK7,IGSF1,LIX1,IL6ST,INPP1,KCNC1,KCNC2,KCNJ3,KLHL23,KCNK2,KIF5C,KLRC3,STXBP5,STMN1,LIG4,LIMS1,VWA5A,ARHGAP12,SMAD9,MAP6,LYPLAL1,LRP1B,MEIS2,PPM1L,AFF1,MOBP,SAMD5,MSR1,ZNF92,MDGA1,MXI1,MYT1,NDP,SFR1,NEUROD2,SLCO1C1,NFIA,CNOT4,NOVA1,ODF2,LOC100128398,SNTG1,PAX6,PCDH8,PCSK1,PCSK5,PCSK2,PDE1C,PDE4D,PIRT,NALCN,PURG,TRHDE,MAPKAP1,SPATA6,RETREG2,SLC36A4,FAT3,CRLS1,PRKACB,PRKCB,PRKCZ,PRPSAP2,RELN,WBP1L,SIDT1,MDGA2,QRICH1,PSMD13,PTHLH,TMEM260,ZSCAN32,PTPN13,FAM120C,PTPRZ1,RIPOR1,CCDC40,RALGDS,IQSEC3,SUSD4,ARID4A,RBBP6,ZYG11B,RET,FIGN,SLC25A36,LGI2,KLHDC8A,CARF,ROBO2,ZC3H14,GLDN,PRR5L,ADAL,ACER3,CNTNAP3,MEG3,ABCA11P,ATAT1,KCNIP3,TRAPPC13,SEMA6D,SLC30A10,SH3GL2,SH3GL3,MYO18A,SHC4,FHOD3,NLGN1,NUBPL,DHX30,RAB3GAP1,SLC8A3,CCDC88A,SLC15A2,TMEM132D,EFHD1,SLCO1A2,RCOR3,ANKRD36,CMTR2,SNRPN,MYO16,MYT1L,SOX5,KDM3A,SP2,CLUAP1,HECW1,MYCBP2,TEX2,NPAS3,C11orf87,ERBIN,SEPT8,CEP68,SULF2,FGD4,ARHGEF9,SYT1,ANKRD28,PJA1,MCF2L,DNMBP,ADGRL3,ANO4,ACSL6,DMXL2,USP22,WDR7,SYNE1,RALYL,SIRT1,SLC44A1,ARL10,ZFP91,HEY2,TP53BP2,C9orf85,PDSS1,TRPC1,PPIL6,TSC1,TMEFF2,LINC00689,DNAJC12,PLEKHH2,VSNL1,XRCC4,ZIC3,ZNF28,AGMO,FMN2,LYPD6,SPHK2,CELF4,ANKS1B,INTS3,CA10,EMSY,SLC38A1,STMN4,PRDM8,TMEM178A,PCDH15,PAK5,PHTF2,NETO1,SLC4A10" MicroRNA hsa-miR-3169:mirSVR_lowEffct hsa-miR-3169:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-161 8.80E-158 6.98E-160 6.43E-159 413 1727 "RALGAPA1,ASIC2,ACTN2,ARID1A,XKR4,TMCC3,GALNT13,SORCS1,PWWP2A,ZNF608,INTS2,KIAA1324,AMPD2,ZFAT,EP400,LCORL,MAP4K3,CNTNAP1,APLP1,VAT1L,USP37,APP,LGR5,PPP4R4,TMEFF1,ASPH,DACT3,PCDHGB4,CHRD,SLC4A4,ATP2B1,BCL2L2,MIR9-3HG,NRP2,KSR1,BMP7,SYNJ2,LINC00906,OSGIN2,MYRF,CFAP410,CA12,CALB2,NGB,CAMK2D,CAMK2G,CANX,ARHGEF25,LDB2,INA,TMEM257,ENTPD6,REPS2,CDC25B,CDH10,CDH18,CDO1,CLGN,NUMBL,RCBTB2,ASIC3,PLEKHB1,CASC2,SYNPR,KMT2C,CLCN4,NMT2,CLTA,TMEM59L,FBXO7,LY86,NIPBL,CNR1,ARMC8,LETMD1,RCHY1,COX4I1,ZFP28,MFSD4A,NECTIN3,ANKRD44,TRIM69,LRIG1,FEZ1,SUSD5,NCAN,PNPLA8,CTNND1,DCAF4,NOS1AP,GPRASP1,ARHGAP32,MAML1,IP6K1,ZBTB24,PLEKHM1,HP1BP3,KLHL3,LYPD1,SV2B,RABGAP1L,SEC16A,DLX1,DNM1,USP3,DYNC1I1,NR1D2,CDON,DNM2,DPH1,ACOT8,ABI1,TOM1,KRBA2,GOLT1B,SGK2,FSD1L,SIDT2,RBM12,SH3GLB1,EGFR,RGS17,TMEM35A,PAN3,EIF1,EMX2,RCAN2,ANKRD13B,NCALD,TMEM74,RASL12,SIRPB1,F8,ZIC4,SCML2,CORO2B,DLC1,FCGR1A,CEP78,CHST15,TOMM40L,FCGRT,ZSCAN30,OLFM1,FGF13,FGF14,CAMSAP1,EVL,SEMA4D,ATP13A4,FLT1,NOP56,SYT3,SORBS1,HVCN1,RASL10A,HHIPL1,TBR1,GABRA1,CHL1,GABRB1,GABRG2,HBS1L,ZMYND11,B4GALNT1,RAPGEF6,IP6K3,DISC1,ALDH1L1,PCDH17,TTBK1,GNG4,ATF7,GPR12,NUDT21,GRIA4,ADAMTS13,GRM2,ZBTB49,MUM1,IRAK3,MAEL,HMGCL,HNRNPK,NEGR1,LRRC75A,SHISA6,CELF5,HTR5A,USP54,IL6ST,KCNB1,KCNK1,CREG2,LIMS1,PIK3AP1,MAP2,MBP,SYT9,ADAM11,KCTD6,XRRA1,MOBP,MOG,ERICH3,ZNF680,MSR1,MSRA,PTOV1,ZNF862,TCEAL5,NAP1L3,NCAM1,CCDC13,NEUROD1,NFE2L2,ALDH1L2,NOVA1,DNHD1,DDR2,GPR88,OPA1,P2RX7,PBX1,DPY19L2P2,PCDHGC3,PCSK5,ENPP2,PFKFB2,PFKFB3,PIK3R1,GPSM2,FTO,PLTP,PRIMPOL,C11orf49,PSAT1,PRKAB2,GRAMD1C,HYDIN,APTX,SIDT1,GON4L,WDR25,PIGG,PTPRB,PTPRE,CASTOR1,PTPRG,PEX2,ZSCAN2,QDPR,NWD1,RAP1GDS1,ZNF493,RASGRF1,RASGRF2,DBX2,RADX,KHDRBS2,ZDHHC14,ZMAT4,PRRT2,RFX2,UBR7,KIF7,RIC8B,ZFHX4,LGI2,C12orf49,KLHDC8A,ALG9,KIRREL1,RPE65,BAALC,SPIN3,ZC3H14,ATP8B4,GLDN,ADAL,STK32B,CNTNAP3,SYNDIG1,ABCA11P,ST6GALNAC6,ZNF354C,FAM192A,ATXN2,LRRTM4,FAM19A1,SCN8A,LINC00461,PRCD,ASIC4,SUPT20H,ITSN1,FAM102A,MYO18A,WDR37,ZNF365,SLC2A5,PEX26,FAM214B,SLC6A9,SLC8A3,ELMO2,SPHKAP,ABTB1,TTC17,IFT122,LIMCH1,SNCA,CABCOCO1,SNRPN,SCN3B,TSNAXIP1,UNC5B,RBM26,NPAS3,SRPK2,STOX1,EPB41L3,NKAIN2,ST5,NCDN,MAPK8IP3,STAC2,SULF2,SEPT3,FAM168A,SYNE2,SYN1,TAC1,MMS19,ATP11A,TACR1,ADGRL3,WWC1,TBCEL,TBL1X,ANO4,ATMIN,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TMEM151B,RALYL,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZNF106,CDH22,TIAM1,HEY2,TMPO,DAAM2,TNS1,CHST5,SYNPO2,PDSS1,TRPC1,ZMYND8,PPIL6,TMPRSS5,TMEFF2,TUBB1,PITPNB,OSBP2,ZNF709,MEAF6,CFAP52,ATP6V0E2,FMN2,NDRG4,CRB2,MKRN3,ZNF138,PLPPR5,GDPD5,LMAN2L,NAV3,NAV2,CAB39L,SLC17A6,FZD3,ST7,UBE3B,FBXO36,TRAM2-AS1,VANGL2,TTC7A,IFT88,CBLN2,AP3B2,SOCS4,SLC4A10" MicroRNA hsa-let-7a-2*:mirSVR_highEffct hsa-let-7a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-161 1.02E-157 7.99E-160 7.36E-159 351 1242 "RALGAPA1,DGCR6,KCNH8,CLK4,ARID1A,KLHL32,DSCAML1,AXIN2,ADRA1D,BEND6,OSBPL1A,TBC1D14,LRRC7,SPARCL1,ABCD2,PCDH10,UNC79,FAM135A,SYT13,OGT,ANK1,MAP4K3,CNIH2,ALS2,PHYHD1,BCAS1,APP,TMEM263,DACT3,CHRD,NUMB,RASL11B,ATP2A2,ADGRB2,BCHE,DCAF5,NRP2,SYNJ1,MTMR2,OSGIN2,BSN,IL33,CACNA1D,KALRN,PTBP2,MAP7,AP4M1,LRBA,CDH10,LGI1,MAGI1,SRSF11,CHN2,NDST3,LHX2,CLCN4,LY86,AKAP7,IQCK,LETMD1,SLC4A7,AKAP12,HAPLN1,CS,LRIG1,MICAL2,PLCH2,SOCS5,PDE4DIP,SLITRK5,ST18,USP6NL,HDAC9,TCAF1,KIAA0586,IST1,TOMM20,IP6K1,ZEB2,COPS7A,CEP170,MAGI2,ALKBH8,SMG7,SNAP91,DLX1,HS3ST2,USP3,DNAH9,NR1D2,CDON,CPEB2,DTNA,ABCC5,E2F5,EBF1,EDNRB,PHF20L1,MBNL2,EGR3,TENM1,ELAVL2,PLEKHA1,MRNIP,RGS17,EPHA5,GPHN,CEP85L,RTN3,EYA1,CLVS1,EFEMP1,DLC1,CEP78,FGF13,MEX3B,SYNCRIP,SLC37A3,DCTN2,C2orf88,NBEA,SORBS1,HVCN1,STAMBP,CAMKK2,CSPG5,ZNF512,STAG2,MEGF11,GABRA2,GABRA5,GABRB1,ZMYND11,GALR1,SALL3,NEK6,ZNF559,KIAA1841,AHDC1,GFAP,PPARGC1A,KIRREL3,GLI2,GLS,KDM2B,GNAL,FERMT2,GPM6B,GRB10,DIDO1,C1QL4,GRIK3,GRM7,ZNF496,CIT,PTPN5,KAT7,LINC01551,LINGO1,GYG1,ARHGAP36,BACH2,HMGB1,HNMT,ZNF491,SHISA6,SMAP1,SOWAHA,KNDC1,RIPPLY2,INSM1,LRRTM3,ITGAV,JAK1,METTL21A,KCND2,KCNH2,KCNJ16,KCNK1,KCNK2,KIF5C,KLC1,STXBP5,LAMP2,INSYN2,VWA5A,ARHGAP12,NCOA7,LSS,ASPRV1,NAT8L,MAP4,MBNL1,SHC3,MN1,HS6ST3,MYCN,NAP1L1,NCF2,OTOGL,NODAL,NPTX1,HCN1,NTRK2,NTRK3,CLDN11,PBX1,PCDH8,PCSK1,PCSK5,PDGFRA,ENPP2,NLGN3,CAMKV,PIK3C2A,ZNF655,FAM218A,A2ML1,ZFYVE21,ING3,NXPH1,TATDN3,PPP2R5C,SAMD9,WBP1L,SNRK,PTK2,TMEM260,EML5,USP47,RASGRF1,FEZF2,REV3L,RFX4,RGS7,PRIMA1,ARHGEF10L,SLC25A36,PBRM1,TMEM100,SNX22,NEK11,MAP6D1,LGR4,MEG3,TRAPPC13,RMI1,SALL1,SCN2A,SGK1,ITSN1,SH3GL2,ARX,KIF16B,CPEB3,DOCK10,NTNG1,FNDC3A,SLITRK3,ANKRD6,WDR37,SLC20A2,SLC22A4,RIMS1,SNCA,MBD5,KDM4B,SON,PDZD2,MYT1L,SOX10,KDM3A,MYCBP2,ZC3H13,TAB2,ATP10B,CLASP2,TROVE2,ZNF302,EPB41L3,ZC4H2,LARP4,NKAIN2,ERBIN,STAU1,NSFL1C,KLHL7,NUDT10,DNAJC9,PLCB1,MMS19,DDHD2,CAMTA1,TAL1,ADGRL3,TCF7L2,ZEB1,WDR7,DOCK9,RALYL,FAM189A1,PCDHB4,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,SLC44A1,TJP1,TMPO,R3HDM1,KAT6B,SEZ6L,NPL,TPM3,RGMB,TRIO,RPL7L1,EIF4ENIF1,DNAJC12,FLRT1,PLEKHH2,BCL2L13,VLDLR,ZIC2,ZIC3,MKRN3,ZNF142,REEP1,FTSJ1,EMSY,MDH1B,PCDH15,NAV3,PCBP4,MPPE1,MVB12B,PDSS2,FAM13C,KAT6A,FBXO36,FAM219B,JMJD1C,VANGL2,FXR1,NETO2,SENP7" MicroRNA hsa-let-7e:mirSVR_lowEffct hsa-let-7e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-161 1.64E-157 1.28E-159 1.18E-158 443 1985 "TTYH1,AS3MT,GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,OLMALINC,AP2A2,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,ANK3,LCORL,PHF12,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,SHROOM2,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM23,ADAM15,MPDZ,NIPA1,CACNB4,CALM1,PTBP2,SYT6,CAST,MAP7,NFS1,ZNF501,USP6,SLC16A4,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,LARGE1,TIGD7,CLGN,GPR37L1,ASIC3,MS4A7,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,CLIP3,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,CMTM5,GREB1,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,DCT,ZBTB24,MED24,BLOC1S6,DDX46,POM121,SNAP91,TMCC2,GRIN3A,CPEB2,DMTF1,DPH1,PDCD6IP,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,SNX29,EDNRB,ANKRD46,SIDT2,YAF2,EFNB3,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,EPB41L2,COQ7,DMTN,EPHB1,RABEPK,CDHR1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,CHST15,TOMM40L,GTF2IRD2,FGF1,CAP2,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,CAMKK2,ATP6V1H,ZNF605,ERGIC3,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,ATP8A2,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,GSTM5,BVES,FICD,AP4S1,LINGO1,ATOH8,MAEL,HAS2,TOX2,LINC01102,HLF,HMGCL,ZDHHC15,OPALIN,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,MYO9A,PABPC1L2A,NDUFA5,SFR1,NEFM,ALDH1L2,NME4,NOVA2,DNHD1,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,OXTR,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,ZNF655,PLCB2,PLP1,HMGCLL1,PLXNB1,C11orf49,TRHDE,SCHIP1,RETREG2,RANBP3L,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LAMA1,DEF8,WDR25,PIGG,PTAFR,UHRF1BP1,TMEM260,PTPRD,PTPRG,PTPRO,FAM120C,NKAIN1,SH3TC2,NWD1,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,GAL3ST4,SLC6A15,TRIM68,KCTD17,RIT2,ZNF532,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,UEVLD,KIAA0895L,ACER3,TCP11L1,PTGR2,RTKN,TRAPPC13,ATXN2,HOGA1,SCN4B,PRCD,ASIC4,SEC14L1,TRIM46,CASC3,STUM,FOXRED1,HSPA4L,ITSN1,CPEB3,ST6GAL1,CTXN2,WDR37,SLC1A7,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,SLC8A2,ATF7IP,CPEB4,MAST1,MYH15,IFT122,INAVA,FAM126B,RBM34,USP33,FAM219A,DOP1A,SPATA7,KDM3A,KDM4C,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,NFASC,TAB2,POGZ,ITPRID2,SSTR2,ZC4H2,SYT11,MLC1,FNDC9,PLCB1,COBL,SLC37A2,TAC1,FAM208A,PDLIM2,FBXW11,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,HIF3A,SIK3,RNF216P1,DICER1-AS1,AP4E1,ARL10,TIMP4,TK2,ERCC6L2,DAAM2,KCTD2,TNFRSF1B,C5orf64,NPL,TPM3,C9orf85,CHST5,SMUG1,TRIO,STXBP4,TRPC3,NTSR2,TSC1,TTTY15,PRR18,ZKSCAN5,CLHC1,SLC35A4,AMOT,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF708,ZNF28,ZBTB16,EML6,MEIS3,WNK1,CSDE1,EVI5,LINC02210,FIP1L1,TRIM16L,PARP11,FBXO36,CASC15,NUP214,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-888:mirSVR_lowEffct hsa-miR-888:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-161 2.02E-157 1.56E-159 1.44E-158 443 1986 "RALGAPA1,ABR,NBAT1,ACTN2,ARID1A,ADAR,SLITRK1,ADD1,BRAP,PTCHD1,ADRA1D,KIDINS220,NLGN4X,SLC24A4,PCDH19,OSBPL1A,TXNDC16,CC2D2A,HFM1,SEMA6A,SRPX,ABCD2,FAM135A,TRMT9B,ZFAT,PPFIA4,PKP4,ANXA7,APBB2,GAS7,UPRT,CACHD1,VAT1L,APP,SHROOM2,AQP4,CDC14B,SEMA4G,PPP4R4,CASK,TMEFF1,SPTBN4,ARHGAP5,ZBTB10,NCOA1,NUMB,DDX3Y,TMEM108,B3GALT2,NOL4,ATP6V0A1,SEC11C,DCAF5,NRP2,PROM1,FUBP1,LINC00906,BTK,GYG2,GPC2,CACNA1E,DDR1,CACNB4,PTBP2,TRIM41,SYT6,CAST,NFS1,ZNF501,CD86,CD38,REPS2,DCLK1,CCPG1,CHN1,CASC2,LHX2,NRXN1,CLTA,CLTC,CNN3,ARHGEF6,CNTFR,FAM149A,TBPL1,RTTN,ZFP28,HS3ST5,CHD1L,FAM171B,PNKD,RBM39,CS,MICAL2,CSNK1E,OSBPL3,CSNK1G3,DZIP3,APPL1,RUBCN,KIAA0408,MATR3,KIAA0586,SCRN1,IP6K1,DBI,DNAL1,ARMCX4,SPATA2,YTHDC1,ZEB2,MFAP3L,KIAA0319,SV2B,DLG2,DLX1,EXOG,DMD,USP3,SLC12A6,GNE,MAMLD1,AASDH,SEZ6L2,PHC2,HIPK3,RASGRP1,SH3GLB1,CELSR3,MRO,EGR3,EIF4G2,EIF5,COPS4,USPL1,EPB41L2,STX2,ETV1,RTN3,EXTL2,ECSIT,NSRP1,FAM198B,WAC,SH3YL1,TMEM132C,KIAA1109,POLR1B,SPSB4,FGFR3,POLK,SUCO,MEX3B,CAP2,IQCG,SGIP1,FAM49B,PRELID3A,ERGIC3,GPR153,PNMA2,SARAF,AP4B1,TVP23A,OGA,STAG2,ZMYND11,GALC,GALR1,SRCAP,GDF9,GFRA2,PCDH17,GK,DBF4,SPIN1,MSL3,GLUL,ZNF638,OS9,GNAO1,GPM6A,TDRKH,FUT10,STON1,TMEM121B,PCLO,GRIA4,RFFL,GRM3,GRM7,KIF3A,FAM19A2,RNF165,PTPN5,GSTM5,KAT7,BVES,SOX21,PSIP1,ADAMTS6,ATG4C,RASSF8,PADI2,MIER3,HMGB1,HNMT,ZDHHC15,HSF2,IGF1,NIM1K,TJAP1,USP54,DIPK1A,RIPPLY2,INSM1,TUBB2B,ITGA7,ITGAV,ITPKB,KCNA1,OLFM3,KCNJ3,KIF2A,IPO5,KTN1,LRRC4B,INSYN2,LIMS1,PAXBP1,SYTL4,ARHGAP12,NCOA7,ZNF667-AS1,MAT2A,MEIS1,MKLN1,AFF1,ZNF680,N6AMT1,RSPO2,SAMD14,MYO9A,NAP1L2,NEUROD1,OTOGL,NPTX2,HCN1,NTRK2,GPR88,CHAMP1,OPA1,OPHN1,SNTG1,PAX6,PCDH8,PCSK5,PDCD2,PDE3B,SLC10A4,SSH1,PIK3C2A,ANLN,PIK3R1,ZNF655,CCSER2,ST8SIA5,PRIMPOL,PNMA3,LRP12,NXPH1,LRRN3,PRKAB2,RASGEF1B,CEP41,RAB39A,MAPK7,CNNM2,SAMD9,WBP1L,LAMA1,CNTLN,PTCH1,PTK2,PXK,FAM120C,PTX3,PEX2,TUG1,PLEKHB2,FAM66C,ZNF793,SH3TC2,FAM184A,RAP1GDS1,ENOX1,OXR1,RASGRF1,ARID4A,DBX2,RBBP6,HKR1,ZYG11B,RGS12,RNASEL,LGI2,RERGL,DCUN1D2,ALG9,PNMA8A,YY1AP1,GLDN,TCP11L1,FAM161B,RPS20,YJEFN3,TRAPPC13,ATXN2,SCN2B,LRRTM4,FAM19A1,SCP2,SLC30A10,SEC14L1,SELL,TRA2B,PPP1R9A,SH3GL3,PPM1E,KIF16B,DOCK10,NTNG1,SHC4,FBXO11,FNDC3A,CTXN2,ZNF365,SLC1A3,FAM81A,PPP4R3A,SMTN,KANSL3,PKNOX2,YPEL4,SEPHS1,SLC12A2,TMEM132D,SLCO1A2,IFT122,SNAP25,SNRPN,TMCC1,RBM34,SOX1,SOX2,SOX5,BDP1,DOK5,SP2,MYCBP2,ZC3H13,ARHGAP26,CDK19,NFASC,TAB2,COLGALT2,ITPRID2,STOX1,SSTR2,NKAIN2,STAU1,CEP68,DIP2A,STXBP1,FGD4,ZFR2,SYN2,SLC37A2,C12orf76,TACC1,KIAA1107,IQCE,WSCD1,OBSL1,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CYB561A3,DICER1,CRB1,C18orf54,ITGB3BP,CSMD1,TPM1,TPM3,CHST5,ZMYND8,TSC1,SSBP2,ZKSCAN5,TMEFF2,CADM1,SLAIN1,MTCH1,TBC1D15,WIPF1,RICTOR,ZIC2,ZIC3,ZNF24,ZNF28,CFAP52,ZNF154,ZSCAN26,ANKS1B,SPIRE1,SLC30A4,PMEPA1,ZXDA,CADM2,SHD,SLC38A1,EVI5,LINC02210,LMAN2L,ADAMTS9,PCDH15,PARP11,SMIM8,PHTF2,CASC15,KLHDC1,FRMD6,NETO1,RNF146,CBLN2,SLC4A10,SENP7" MicroRNA hsa-miR-324-3p:mirSVR_lowEffct hsa-miR-324-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.81E-161 2.14E-157 1.65E-159 1.52E-158 435 1917 "TTYH1,ABCF1,ABR,ASIC1,RBM10,CSMD2,NDRG2,ADCY2,ADCY6,ADD2,SORCS1,FZD9,ADORA1,ADORA2A,KIAA1211,ADRA1B,AP1B1,SNX32,PCDH19,OSBPL1A,C1QTNF1,ADGRF5,ALAD,CARNS1,GOLGA7B,FAM135A,MRTFA,KIF6,FGD2,MYH7B,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,KCNAB2,APBB2,DGKZ,UPRT,GPAM,PPFIA3,MADD,SPTBN4,ARNTL,CDK13,CHID1,CCDC181,ZNF583,SLC2A11,RNF182,CADM3,NOL4,TTLL9,AZGP1,BCL2L2,CACNA1I,CACNB2,KALRN,NGB,ARHGEF25,LDB2,USP6,AIFM1,CD86,CDC25B,IGFN1,COPB2,CBARP,CHGA,CHGB,ASIC3,PLEKHB1,KMT2C,NRXN1,MYL6B,FBXO7,TJP2,IGLON5,ARHGEF6,SUMF2,SMARCAL1,MFSD4A,CHD1L,SEC31B,SH2B1,SLC32A1,GDA,SNCAIP,CSF2RA,FEZ1,MICAL2,PLCH2,SLITRK5,SDC3,CFAP61,GPSM1,RUBCN,CX3CR1,KATNAL2,PHF19,EARS2,PHYHIP,DGKG,TOMM20,ARMCX4,TIAM2,MFAP3L,COPS7A,C2CD2L,LYPD1,POM121,SGSM2,G3BP2,CHRDL1,DMD,DPYSL2,TOM1,DNM1L,AASDH,EDN1,EDNRB,PHC2,CNNM1,RASGRP1,SIDT2,EFNA3,CELSR3,FAM13A,TMEM132E,ING4,TNK2,C3orf18,CALCRL,LRRC23,RASGRP2,SRRM1,EFS,SPEG,MRPL37,RCSD1,RASL12,MRVI1,CLVS1,FABP7,TMEM132C,PTK2B,PRAM1,TUBB3,DLC1,FCGR1A,FGF11,SPSB4,BAIAP2,CAP2,FOXF2,ZCCHC17,POMT1,KHDRBS3,CELF1,GPR153,DLL3,KBTBD12,HHIPL1,TPPP3,TMEM151A,AP4B1,DOT1L,FYB1,DKK3,GABRB1,BRPF3,B4GALNT1,JPH4,ARPP21,ZNF234,GHDC,TMEM8B,DISC1,SEPT9,INPP5K,CPLX2,ALDH1L1,TUBA8,GFAP,GFER,USP19,HEPN1,KIRREL3,RUNDC3A,BRD8,RND1,PCDH11X,ZNF782,GPD1,CCDC184,TMEM121B,GRIA1,DIDO1,C1QL4,ADAMTS13,GRIN1,GRIN2C,GSN,CLASRP,PTPN5,KAT7,PADI2,GPR45,PTGDR2,MAN1B1,NCKAP1L,KLF12,AGBL5,ZNF491,DHX35,SHISA6,HTR5A,FAAP20,ATCAY,ICA1,IRF8,MSL1,MYLK2,KNDC1,IL6R,TMEM240,INPP5B,ITGA7,CDH20,KCNA6,KCND1,KCND3,KCNH2,KCNJ9,KCNJ10,KCNMA1,KLC1,STXBP5,L1CAM,STMN1,SFXN5,MAG,MAP6,MEIS1,MEIS2,MGAT3,SCAMP5,AFDN,XRRA1,MOBP,GIT1,JAKMIP3,TMEM249,MDGA1,NCAM1,NELL2,NF1,CNOT4,DNHD1,NRGN,NTRK3,NUMA1,GPR88,ZDHHC22,PDE3B,PDE4A,PDE4B,BEST3,OLA1,DUSP26,SNX10,PLCB2,ST8SIA5,PRIMPOL,STRN3,RC3H2,ING3,RETREG2,TNPO2,POU3F2,POU6F1,MED1,TATDN3,PPP3CB,KANSL1,HYDIN,WBP1L,TMEM104,PSMD13,PTN,PTPRB,CASTOR1,PTPRG,NKAIN1,RAB3IL1,RAB5B,USP47,PLEKHB2,RALGDS,IQSEC3,SLC25A41,RAP1GAP,FEZF2,GAL3ST4,TRIM68,RFX5,ZDHHC4,RGS3,KIF7,LGI2,MYH14,EXD2,KLHDC8A,ARMC5,KIRREL1,SNX22,EPHA10,KIAA0895L,ZNF671,ATP8B4,SGSM1,STK32B,PTGR2,MEG3,ABCA11P,HSD11B1L,ATAT1,KCNIP2,SATB1,SBF1,SCP2,HES6,SEC14L1,GALNT10,SFPQ,PPP1R9A,PPM1E,SHC4,CHD9,NLGN1,ST3GAL3,PEX26,EPN2,LRRC55,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC11A1,SLC12A4,SMARCC2,CDK5RAP2,MAPKBP1,SNRPN,PALLD,UNC80,USP33,FAM219A,PDZD2,WDTC1,TRERF1,KIF21B,BDP1,TSNAXIP1,ZSWIM8,NMNAT2,ENKUR,KDM4C,ERC1,SPTB,ATP10B,SMOC1,LRRC4,NCDN,INKA2,SEPT8,AJAP1,GSE1,SYT11,ZFR2,VAMP1,NUDT10,TMEM150C,CAMTA1,EXOC7,WWC1,ANO4,TBX15,NEU4,CUX2,SZT2,WDR7,SYNE1,TNS2,FRYL,HIF3A,CYB561A3,RNF216P1,PMS2CL,LEFTY2,ZNF34,FBXL16,TJP1,BEX4,TNFRSF1B,LILRA4,TPM1,NPL,ZNF346,PRMT8,TRH,PPIL6,FNDC5,TUB,UBTF,PLEKHH2,LMF1,NSD2,KLC2,RICTOR,LGI4,ELFN1,SLC26A10,MKRN3,PCBP1-AS1,WNK1,MAP3K12,SLC38A1,XKR7,SEMA3B,SIGLEC10,SLC17A7,PPP1R3F,PCBP4,SMIM8,ADAMTSL3,RNF170,FAM181A" MicroRNA hsa-miR-3126-5p:mirSVR_lowEffct hsa-miR-3126-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.98E-161 2.80E-157 2.14E-159 1.97E-158 409 1699 "KCNH8,ACADM,ASIC2,KDM5D,FAM43B,ADAR,PLEKHG5,GALNT16,ADCY2,ADCY6,ADD1,ADD2,AXIN2,ADORA1,PCDH19,TBC1D14,C1QTNF1,ADGRF5,GOLGA7B,FAM135A,ZNF687,DOC2A,AMPD3,KIF6,LRFN1,LCORL,GPAM,DGKD,ALS2,PHYHD1,SEMA4G,MADD,ARHGDIA,MARCH3,BRINP2,ASTN1,ALDH4A1,EIF4G3,STX16,ATP2B3,ZNF583,SLC2A11,ATP6V1G2,ADAM23,CARMIL3,AZGP1,MPDZ,BCL2L2,KSR1,DST,BSN,CALB1,CALB2,DIRAS1,NGB,CAMK2A,CAMK2D,CAMK2G,VXN,CAST,RUNX1T1,MTMR7,SCARB1,SYNGR3,CD81,CDK11B,LRBA,ZMYM4,LARGE1,CRLF1,CACNA2D2,CHRM1,CASC2,LHX2,TMEM59L,FADS2,LY86,IGLON5,CNN3,SLC25A27,SUMF2,COL11A2,SLC4A8,ZFP28,IGDCC3,CNRIP1,CLOCK,PREPL,RBM39,CRMP1,HINFP,GDA,CS,CSF1R,ARHGEF10,MICAL2,CSNK1E,OSBPL3,SUSD5,ATRNL1,VCAN,RASGEF1C,ERC2,DCAF4,BOC,FGFR1OP2,ARHGAP24,ZFYVE16,TM9SF4,PHYHIP,IST1,DGKG,SPOCK2,DNAL1,ARMCX4,C8orf34,CEP170,ALKBH8,POM121,SRGAP3,SGSM2,CHRDL1,EXOG,DNM1,DNAH9,TRAPPC9,DMTF1,FAM57B,DPP6,ECM2,DNAJB6,ABCC9,ANKRD46,CACNG7,SUGP2,APH1A,EGFR,MRO,MBNL2,IRAK4,C3orf18,CALCRL,EPB41L1,CEP85L,CDHR1,MRPL37,RASL12,CLVS1,ABCA8,PTK2B,ZIC4,TUBB4A,FKTN,KAT8,MED12L,KIAA1109,OLFM1,FGF12,FGF13,TMEM164,AMOTL2,FHL1,CAP2,SEMA4D,FLNC,FLT1,ANKFY1,EFCAB2,SPECC1,ARFGAP2,PRELID3A,DACH2,NRG3,ABLIM2,DKK3,CHL1,GABRB1,GABRG2,HBS1L,BRPF3,ZNF234,ZNF274,NCKAP1,ERAP1,TMEM8B,DISC1,GFRA2,GLS,POLL,GNAL,GNAO1,ZNF782,WDFY3-AS2,GPD1,GPM6A,TDRKH,TMEM121B,ADAMTS13,GRIN2D,GRM7,ZNF496,CLASRP,TMEM25,KAT7,AP4S1,FAM107A,ADAMTS6,RASSF8,ZHX1,HMGB1,HNMT,CELF5,FAM95B1,LRRC25,ZNF678,INSM1,NME9,KCNJ3,KCNJ10,KCNN2,KLRC3,TTYH2,STMN1,SFXN5,VWA5A,MAN2A2,ZFYVE27,AQP11,TM6SF1,MDM4,KCTD6,SCAMP5,MOBP,MPP2,ERICH3,DBNL,SAMD5,MSI1,ADAM22,CTNNA3,MYO9A,FXYD7,NCAM1,CCDC13,NHLH1,NOS1,DNHD1,NUCB1,SETD4,OCRL,LOC100128398,ZDHHC22,PALM,CNTN3,DPY19L2P2,PDCD2,PDE3B,PDE4A,TMIE,PIK3R1,PLCB2,SLC25A23,MTRF1L,PLXNB3,MAPKAP1,EPB41L4B,PACSIN1,NXPH1,PPP1R1A,CRLS1,PPP2R5E,VSTM2L,PRKCZ,MAPK10,CNNM2,CYBC1,CNTLN,UHRF1BP1,NCR3LG1,ZSCAN32,PTPRB,CASTOR1,PTPRN,RAD51D,ZCWPW1,ZNF493,RASGRF1,ZDHHC14,TRIM68,RGS3,RGS4,KIF7,KIRREL1,YY1AP1,PCMTD2,CCDC102B,RPL15,SGSM1,TCP11L1,MEG3,HUNK,HSD11B1L,ATAT1,WLS,ZNF331,CCDC112,HOGA1,SCN4B,TNFRSF19,ASIC4,ELMOD1,SEC14L1,COPZ1,SCAF8,SGK1,ITSN1,PPM1E,FERMT1,KIF16B,R3HDM2,NLGN1,SLA,LIMS2,LRRC55,SLC11A1,ELMO2,EFHD1,TET1,SLIT1,EPC1,INTS9,ANKRD36,KIF13A,SNRPN,TMCC1,WDTC1,KDM3A,HECW1,KDM4C,PEG10,KIF1B,SPART,NFASC,ITPRID2,SST,SSTR1,ZC4H2,MAPK8IP3,ZSCAN29,STAC2,STX1A,GANAB,STXBP1,ADAMTS17,PLCB1,SYN2,SLC37A2,TAC1,KAZN,UNC5D,ADGRL3,TBCEL,SMG6,TCF4,TCF7L2,DOCK9,PHF24,OBSL1,USP32P1,FRYL,HIF3A,KHDC1,THRA,GZF1,CSMD1,C5orf64,TNNT1,TNS1,RBFOX2,ZNF346,SYNPO2,FNDC5,RUSC1,ANO5,HEPACAM,UBE3A,UBTF,PITPNB,VGF,VLDLR,LMF1,KLC2,LGI4,ZIC3,PLPP4,SLC26A10,MKRN3,POLR3H,SLC30A4,MAP3K12,PRDM2,CSDE1,KCNAB1,WNK3,UBE3B,CASC15,FAM219B,SSPN,DPF3" MicroRNA hsa-miR-522:mirSVR_highEffct hsa-miR-522:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.84E-161 3.28E-157 2.49E-159 2.29E-158 406 1675 "RALGAPA1,SDE2,KCNH8,ASPHD1,CLK4,NCKAP5,XKR4,SLC25A25,FMNL2,CCDC85A,PLEKHH1,KIAA1211,BEND6,MTA3,SLC24A4,GPR158,CASKIN1,OSBPL6,ALCAM,BCAR3,MRTFA,KIF6,CDC42BPA,DPP10,LRCH2,LCORL,PPFIA2,PKP4,DGKD,ALS2,BCAS1,CDC14B,ARHGAP5,ASCL1,ATP2A2,ATP2B1,B3GALT2,BLM,ST3GAL5,MTMR3,MTMR2,CACNA1I,RAB29,KALRN,CANX,VXN,SPAG9,MAP7,NFS1,CCNH,TMEM257,C1orf52,LRBA,CDC27,LGI1,L3MBTL4,DLGAP1,UBE2L6,RCBTB2,SRSF11,CHGB,CHM,KMT2C,FAM19A5,C4orf33,NIPBL,CNR1,CNTN1,ARMC8,AKAP6,SLC4A7,ABI3BP,AHCTF1,RTTN,ACBD5,ZFP28,HS3ST5,ENTPD4,HINFP,ANKRD44,SNCAIP,SUSD5,VCAN,SOCS5,SLITRK5,FGFR1OP2,RIPOR2,ARHGAP24,LIN54,MATR3,KCTD8,DAPK1,ARMCX2,C8orf34,ZEB2,ZBTB24,MYEF2,ZC3H11A,RHOBTB1,SNAP91,KBTBD11,DLG2,GRIN3A,DMD,NR1D2,CPEB2,DMTF1,SLC12A6,DPYSL2,ABI1,DTNA,FAM78B,DNAJB6,DYRK1A,DNM1L,ABCC9,SEMA3D,RBM12,APH1A,KMT5B,ABI2,EGR3,AASS,GOLGA7,IRAK4,TENM1,PLEKHA1,EIF1,EPB41L2,ZNF549,CDHR1,ETV1,VPS26C,RTN3,ADGRV1,EZH1,F5,ARMCX1,CLVS1,AMZ2,ACSL4,DLC1,CHST15,FDFT1,FER,OLFM1,FGF11,FGF12,PRKAG2,SUCO,SYNCRIP,FLT1,NOP56,NBEA,CSPG5,NSG1,NRG3,PHYHIPL,STAG2,GABRB1,HBS1L,AHCYL1,RAPGEF6,GALR1,DISC1,ATP8A2,LRRC37A6P,KIAA1841,GCNT2,SULT1C4,ARFIP1,SESN1,PCDH17,PPARGC1A,RND1,SPIN1,GLS,TOX3,TNRC6A,MSL3,GLUL,ZNF638,INSM2,GNAO1,PRUNE2,GPM6A,GPM6B,STON1,GPR34,CECR2,GRIA1,GRM5,RNF165,LINC01551,PADI2,LINC01102,MIER3,HNRNPK,TLX1,USP51,CELF5,HTR2A,MSL1,IDH3A,SOWAHA,C5orf24,RBPJ,DOCK7,USP54,DIPK1A,SLC35G1,KCND2,KCNJ16,KCNK2,KCNN3,CREG2,KIT,KLRC3,CYP27C1,STMN1,LMO2,NCOA7,NAT8L,MAOB,MAT2A,MATN2,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,MRPL42,BLOC1S2,ADAM22,MTTP,MX1,MYO9A,HNRNPM,NAP1L2,NCAM1,NCAM2,NDP,NDUFA5,NEUROD1,NOVA1,SLC11A2,HCN1,TBC1D25,IGSF11,GPR88,OPHN1,CLDN11,PBX1,PRTG,PDE3B,PDE4D,PDGFRA,BEST3,CDK14,PIK3C2A,A2ML1,ZFYVE21,TRHDE,EXOSC10,PRRX1,ING3,SPATA6,EPB41L4B,PPM1B,PPP2R5E,PRKACB,DCHS2,SNRK,TMEM260,PTPRB,PTPRE,PEX2,ACSM5,CCDC40,SH3TC2,OXR1,RASGRF1,HKR1,RDX,SLC6A15,UBR7,KIF7,LGI2,CCDC82,ZNF532,RAVER2,CCDC25,RPL15,ZC3H14,ZNF671,MCMBP,ACER3,LRRK2,CLIP1,ZNF331,SALL1,ATXN7,SCN2A,FAM19A1,FNIP1,IL17RB,RASA3,SGK1,KIF21A,PPM1E,DOCK10,SHC4,SLC1A3,FAM81A,RPH3A,DHX30,RUFY2,CCDC88A,SLC15A2,BTBD7,SLC22A4,CDK5RAP2,SMARCE1,RCOR3,SNAP25,SNCA,MBD5,SNRPN,PDZRN3,UNC80,WDTC1,NMNAT2,HECW1,MYCBP2,KDM4C,TEX2,SPTB,LMO3,SRPK2,PBLD,POGZ,DIP2A,SULF2,NECAB1,JMJD6,VPS13A,ADAMTS17,SYPL1,C12orf76,MTCL1,CAMTA1,TCEA1,RPGRIP1L,SYNE1,SLC19A3,SIRT1,AP4E1,TIAM1,TJP1,TK2,BHLHB9,ZFP91,HEY2,KAT6B,TPM3,ZNF384,RUNDC3B,TTTY15,PRR18,CADM1,FAM155A,UBE2H,FLRT1,LAT2,PORCN,CLDND1,SLC47A2,PCDH20,ZIC1,ZIC2,KCNT2,LYPD6,ZNF177,SYNC,UPF3A,MAP3K12,LRP8,CSDE1,LINC02210,STOX2,ADAMTS9,TMEM178A,MDH1B,WNK3,PDSS2,EPM2A,DNAH10,FAM13C,MRPL47,PAK5,JMJD1C,RNF170,FRMD6,NETO2,FAM198A" MicroRNA hsa-miR-550:mirSVR_lowEffct hsa-miR-550:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-160 6.66E-157 5.01E-159 4.61E-158 421 1803 "ACLY,AS3MT,SYS1,NDRG3,FMNL2,DSCAML1,SLC12A5,UNC5A,PWWP2A,RNF150,ESYT2,PTCHD1,AP2A2,ZNF608,KIAA1324,WDR35,CC2D2A,CEP126,BCAR3,ARHGAP20,DPP10,ANK1,CCDC146,USP28,PPFIA4,APBA2,APBB1,DGKD,PPFIA3,SHTN1,SFMBT2,LINC00173,STK33,MARK4,STX16,ATP2A2,ATP2B1,B3GALT2,N4BP2L1,KIF1A,TTLL9,ADAM15,ADGRB1,LINC00847,DCAF5,DST,SYNJ2,CA8,THSD7A,CAPN3,SLC16A4,CBFA2T2,SCARB1,SYNGR3,CD38,ENTPD6,CDC25B,LARGE1,MAGI1,CRLF1,CHGA,CHN2,MS4A7,TPP1,FADS2,MAP4K4,ARHGEF6,COL4A5,ABI3BP,COX4I1,ZNF521,AKAP12,CRYBB1,ANKRD44,GDA,CLIP3,CS,CSF2RA,ARHGEF10,SIPA1L1,NCAN,VAC14-AS1,KIAA0040,CTH,PPP6R2,BOC,KATNAL2,HDAC4,PHF19,ZFYVE16,EARS2,ZNF337,LIN54,PHYHIP,TMEM170A,PITPNC1,SPATA2,YTHDC1,ZEB2,MYEF2,ELMO1,GUCD1,SMG7,SV2B,NTM,AK5,KIF19,EXOG,RAB39B,DMD,DNM1,DMPK,USP3,SLC29A4,DMTF1,DPH1,RCAN1,GNE,DTNB,ECM2,MAMLD1,DNAJB6,DNM1L,EBF1,SNX29,EDNRA,ANKRD46,CNNM1,RBM12,SUGP2,ABI2,EPB41L2,DMTN,ANKRD13B,EFS,CEP85L,ZNF549,SPEG,VPS26C,RASL12,SIRPB1,EYA1,GMPR2,MRVI1,HSPA12B,PTK2B,ATP8A1,RACK1,FCGRT,ZNF589,FER,POLR1B,FGF13,POLK,SUCO,CAP2,IP6K2,EVL,FLYWCH1,EFCAB2,APOPT1,ZNF605,NSG2,CELF1,DACH2,CGREF1,B3GAT1,NRG3,MEGF10,GABRA2,GABRA5,GABRB1,GABRB3,FAM184B,SALL3,ZNF274,TMEM8B,C15orf41,DISC1,GATM,SULT1C4,MSTN,CYP46A1,GGT7,GHR,KIRREL3,CRCP,COPS8,GLI2,TOX3,ZNF638,CNDP1,STON1,GRB10,GRIA4,GRIN2C,ZNF496,LINC00839,MFSD2A,RNFT2,PTGDR2,MAN1B1,LINC01102,VSIG4,HMGCL,AGBL5,CPT1C,DHX35,ZNF546,LRRC25,DISP2,IGSF1,SCIN,INPP5B,NME9,KCNC2,KCNJ11,A1BG-AS1,L1CAM,LIMS1,ARHGAP12,MAN2A2,ZFYVE27,MAPT,MBD1,ADAM11,LDLRAD3,MEIS1,AFDN,XRRA1,SAMD5,MT3,N6AMT1,MYT1,NAP1L2,FXYD6,NDUFA5,SFR1,CCDC13,NELL2,NNAT,DNHD1,SLC11A2,NRGN,NTRK3,OGG1,OPCML,P2RY1,PDE2A,PDE4A,PDE1B,PDYN,PFKFB4,FAM218A,A2ML1,XRN1,GPSM2,NLE1,PLIN1,HMGCLL1,PURG,STRN3,PILRA,NXPH1,POU6F1,PPM1B,TATDN3,RASGEF1B,BCAS3,WBP1L,MDGA2,BDNF-AS,PTPRE,PTPRG,RIPOR1,ZSCAN2,RAB5B,TMEM255A,RALGDS,NWD1,SLC6A15,TRIM68,UBR7,RGS4,RGS12,ADAL,STK32B,ABCA11P,HUNK,KCNIP3,SBF1,CSRNP3,DRAXIN,ATXN7,SMPD3,PEAR1,CASC3,GALNT10,KIF27,ITSN1,FERMT1,SHMT2,HKDC1,AMBRA1,ST3GAL3,SEC31A,DZIP1,PREX2,PEX26,DHX30,LRRC55,SLC6A9,YPEL4,ARHGEF40,SLC9A5,SLC11A1,SLC15A2,ELMO2,NAXD,SMARCD3,KIF13A,CMTR2,PDZRN3,KDM4B,USP33,SOX2,SOX11,ZSWIM8,NMNAT2,GLT8D1,KDM4C,IDI2-AS1,UNC5B,SPTAN1,NPAS3,NFASC,LHPP,ATP10B,CLASP2,CLSTN2,STOX1,NKAIN2,INKA2,MAPK8IP3,ZSCAN29,TTBK2,DIP2A,ACSBG1,NUDT10,SYN2,SYT1,TACR1,SEMA4A,CAMTA1,EXOC7,PDLIM2,VWA3A,ATMIN,TCEA1,SIN3B,AZIN2,SYNE1,TMEM151B,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,RNF216P1,ZFPM2,ITGB3BP,TGFBR3,HHIP,CDH22,GALNT17,HEY2,LRRC8A,RIMBP2,C9orf85,RGMB,NEIL2,STXBP4,TTTY15,HIRA,UBTF,UCHL1,PITPNB,CCDC14,BEST1,LMF1,CLIP2,NSD2,RICTOR,GUSBP1,ZNF24,ZNF74,LYPD6,ZNF189,DPYSL5,LRP8,STMN4,PRDM10,CIAPIN1,PCDH15,CAB39L,FAM47E,C12orf4,PDSS2,HNRNPA3,CASC15,SSPN,IFT88,DPF3,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-764:mirSVR_lowEffct hsa-miR-764:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-160 8.97E-157 6.69E-159 6.16E-158 432 1898 "DGCR6,ABHD6,NBAT1,SYS1,TKTL1,ARID1A,CSMD3,ADAR,KLHL32,TMEM132B,SORCS1,ADORA1,RNF150,AP2A2,RTL9,OSBPL1A,OSBPL8,CC2D2A,TAOK1,ALCAM,PCDH10,AMPD2,ANK2,SUGT1P4-STRA6LP-CCDC180,DGKZ,UPRT,GPAM,APOC2,AMER3,KIAA1614,SPTBN4,DNAH17,BRINP2,ASTN1,TMEM108,ATM,EIF4G3,ATP1B3,DPY19L3,RIPK1,CARMIL3,ADAM15,LINC00847,LDHD,NAE1,MTMR2,GPC2,RAB29,WASF1,CDK5R2,MMD2,CA4,CA8,CACNA1D,DDR1,CALB2,TRIM41,CAPN3,ISPD,USP2,P2RX6,CD86,CBFA2T2,ENTPD6,DGKI,CDC42,LRRFIP1,CRLF1,NUMBL,ASIC3,CASC2,JAM2,RAB33A,NRXN3,PPT2,CLCN3,COG1,TPP1,FBXO7,FAM189A2,SULT4A1,SRP14-AS1,CNTFR,ARMC8,FAM149A,SLC4A7,CP,CHD1L,C2CD2,HAPLN1,CLIP3,CS,CSF1,CSF1R,SEC24C,CSNK1E,ATRNL1,SIPA1L1,SOCS5,PDE4DIP,PLXNA4,SLITRK5,KIAA0040,APPL1,CTH,GREB1,RIMS2,BOC,DOCK4,RIPOR2,ARHGAP24,LIN54,DGKB,IP6K1,GIT2,ARMCX4,ZNF804A,HEPH,RUSC2,MED24,BLOC1S6,LYPD1,GUCD1,POM121,SMG7,SV2B,WDR20,DLG2,DLG3,RAB39B,DNM1,HS3ST4,HS3ST2,RPS6KL1,SLC29A4,NR1D2,DNM2,DPH1,ABCC9,SNX29,PHC2,APH1A,EBI3,EGFR,MBNL2,RASA4,VPS13B,EPB41L1,EPHB1,RABEPK,STX2,DENND4A,IGSF6,CDKL3,DNAJC27,MRVI1,F8,DLC1,RACK1,FCGRT,ZSCAN30,FGF11,PRKAG2,MEX3B,HPCAL4,FLT1,NELFCD,WDR83,NBEA,POMT1,APOPT1,NPTN,CAMKK2,NSG2,DACH2,CGREF1,GPR153,NSG1,DLL3,STAU2,B3GAT1,ADGRA1,TVP23A,GAA,GAB1,GABRB1,NCKAP1,LRRC37A6P,MYOZ2,ALDH1L1,ADAM28,FREM1,KIRREL3,TTBK1,COPS8,GLRB,GLUL,PSRC1,LILRB4,GPM6A,TDRKH,FUT10,LILRA2,GPER1,GRB10,GRIA2,ADAMTS13,GRM1,GRM3,GRM7,COQ10A,GSTM5,SOX21,GPR45,FRMD5,HRH3,ATXN2L,HMGB1,AGBL5,CPT1C,RAB41,C5orf24,KNDC1,TJAP1,PLD5,IGSF1,IL11RA,NME9,ITPKB,KCNA2,KCNA4,KCND2,KCND3,KCNJ11,KCNK2,KCNN2,KIF2A,A1BG-AS1,MAG,MAP2,MAP4,MATN3,MBP,CHIC1,LDLRAD3,MID1,MMP16,GIT1,COMMD5,MT3,SCG3,TAGLN3,CTNNA3,LYRM9,MYO7A,NEXMIF,CNOT4,HCN1,NTRK2,NUCB2,OCRL,OGG1,OXTR,P2RX7,ZNF827,PAK3,PAX6,DPY19L2P2,PIRT,PKM,FXYD1,PLP1,ZNF426,MTRF1L,RC3H2,LRP12,EXOSC10,NXPH1,PPP3CB,PKIA,PRKCG,MAPK4,MAPK7,KLK6,PSD,PIGG,UHRF1BP1,DKFZp779M0652,PTPRE,ZSCAN2,QDPR,TMEM255A,CCDC40,RAD52,RAP1GAP,RASGRF2,FEZF2,RBBP8,KHDRBS2,BSDC1,MSANTD2,RGS4,MYH14,TMLHE,CYB561D1,NEK11,RPL15,SPIN3,GLDN,SGSM1,HUNK,HSD11B1L,ZNF568,TRAPPC13,S100B,SEMA6D,DRAXIN,LRRTM4,SCNN1D,SCP2,TNFRSF19,SMPD3,TRIM46,GALNT10,RASA3,SGK1,SHMT2,ST6GAL1,NLGN1,SLC1A3,EPN2,SMTN,PKNOX2,SLC6A8,SEPHS1,RAB3GAP1,SLC8A3,CDK5RAP3,SLC9A5,SLC11A1,SLC15A2,LGI3,SLN,SORCS3,CDK5RAP2,ANKRD36,SNCA,MYO16,UNC80,TSNAXIP1,FNBP1,SP2,ZSWIM8,KDM4C,ERC1,SPTB,KIF1B,CLASP2,LARP4,SSPO,DIP2A,SEPT3,GSE1,NSFL1C,FAM168A,VPS13A,SYN2,SLC37A2,ATP11A,KAZN,ROBO3,CAMTA1,PDLIM2,ALG1,ADGRL3,TMEM136,TBX15,ACSL6,TCF7,SLC19A3,AKNA,ARHGEF12,AHCYL2,HIF3A,DICER1,CRB1,TGFBR3,ZNF34,TK2,DAAM2,TNFRSF1B,TPM1,C9orf85,WBP2,PRMT8,TRO,ANKRD20A2,TSC1,RPL7L1,OSBP2,MTCH1,MEAF6,RICTOR,GUSBP1,SLC13A3,ZBTB14,SLC26A10,ZNF138,ZNF154,REEP1,SPIRE1,SYNC,MEIS3,UPF3A,GDPD5,PRDM8,XKR7,PRDM10,RNF103,HPS4,FIP1L1,MVB12B,C12orf4,PDSS2,RGS7BP,DOCK8,FAM219B,ZNF248,TIGD6,FXR1,IFT88,JPH3" MicroRNA hsa-miR-574-5p:mirSVR_lowEffct hsa-miR-574-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-160 1.13E-156 8.34E-159 7.68E-158 415 1755 "VWA5B2,RALGAPA1,SERPINA3,ABAT,ABCF1,KCNH8,ABR,CLK4,ABHD6,SYS1,CSMD2,ADAR,GALNT16,GALNT13,UNC5A,KIDINS220,KCTD16,OSBPL1A,KIAA1324,ZNF578,BCAR3,FAM135A,ANK1,ANK2,SEMA7A,C6orf89,MAP4K3,GPAM,ALS2,PHYHD1,CDK10,IGDCC4,TMEFF1,CADPS,MARK4,CCDC74A,ASPH,DACT3,NCOA1,NUMB,ATP1A1,RNF182,N4BP2L1,ATP6V0A1,LINC00847,BCS1L,NRP2,CFLAR,ARHGEF7,CASTOR3,WASF1,CACNA1B,DDR1,CACNB4,LURAP1,DIRAS1,CANX,BRSK2,CLDN10,METTL6,RGN,P2RX6,CBFA2T2,TMEM257,LGI1,LOC730101,CACNA2D2,GPR37L1,FOXN3,SLIT2,DLGAP3,RAB33A,IGFBP7-AS1,VAX2,QKI,MAP4K4,ARHGEF6,FAM149A,ABI3BP,IFFO1,ACBD5,IGDCC3,HS3ST5,PNKD,CDC42BPB,CREM,ENTPD4,CRMP1,CLIP3,SNCAIP,CSF1R,ARHGEF10,PHACTR3,CST3,PLXNA4,KIAA0040,NRSN1,PUM1,ZSCAN23,RUBCN,SEC14L5,DOCK4,GAPVD1,PHF19,ZFYVE16,EARS2,LONRF1,TBC1D5,TMEM170A,SPATA2,HEPH,KIAA0753,COPS7A,TMEM130,BLOC1S6,SNAP91,SV2B,AK5,G3BP2,CHRDL1,DLG2,DLG3,DMD,CDON,SLC12A6,DPH1,ATN1,PDCD6IP,DSCAM,DTNA,DTNB,MAMLD1,DNAJB6,EDNRB,TMTC1,FAM13A,EGR3,SORBS3,STARD3NL,EPB41L2,EPHB1,ANKRD13B,RABEPK,SRRM1,CEP85L,SPEG,ETV1,VPS26C,SIRPB1,KATNAL1,ADGRV1,MRVI1,EZH1,NRN1,F5,TAOK3,RACK1,GORAB,SEC24B,GTF2IRD2,FGF1,SUCO,PCYOX1,AGAP2,SYNCRIP,SEMA4D,FLT1,ANKFY1,NELFCD,C2orf88,NBEA,FAM49B,ZNF605,CGREF1,MSANTD4,HHIPL1,TVP23A,MEGF11,GAB1,HRASLS5,BRPF3,ARPP21,NCKAP1,MTHFD2,C15orf41,DISC1,ACSS1,DNER,ADAM28,GFRA2,MALT1,TCERG1,COPS8,GLS,PCDH11X,LUZP2,GPD2,GPM6B,GPR12,GPR22,CECR2,GRB10,DIDO1,GRID1,PLPP7,GRIK2,ADAMTS13,ZNF496,RNF165,GSTT2,BVES,GUCY1A1,CELF3,NXPH3,PTGDR2,HLF,SYNPO,NEGR1,TCEAL6,HSPA1L,ATCAY,IDH3B,NKD1,KNDC1,PLD5,LIX1,SCRT2,INPP5B,NME9,JAK2,KCNJ16,KCNK1,KHK,KIF2A,A1BG-AS1,INSYN2,PAXBP1,SYTL4,NCOA7,MAP2,MAP6,MARK1,LYPLAL1,SYT9,ADAM11,MEF2C,MEIS1,POC1B,MMP16,ZNF680,JAKMIP3,BLOC1S2,NRBP2,SCG3,MDGA1,MYO9A,MYT1,NEK1,NOS1,CNOT4,DNHD1,NTRK2,ZDHHC22,CNTN3,PAX6,ETFRF1,PDE1A,PDE1C,PDE4D,ENPP2,OLA1,A2ML1,FAM216A,MTRF1L,PLXNB1,PSAT1,SCHIP1,TNPO2,POLR2F,PPM1B,PRKACB,MAPK4,HYDIN,DIRAS2,PROX1,SAMD9,BCAS3,SLC22A23,SIDT1,SNRK,QRICH1,UHRF1BP1,PTHLH,PTPRZ1,PTX3,NKAIN1,SLC25A48,CCDC40,SH3TC2,FAT4,NWD1,RAP1GDS1,RASGRF2,RBBP6,GTDC1,RGR,RGS3,TMEM206,UEVLD,GLDN,MEG3,WLS,KCNIP1,STX1B,FAM192A,DGLUCY,SCN4B,SOX6,STUM,TRA2B,KIF21A,SH3GL3,PPM1E,ARX,FHOD3,ST3GAL3,RPH3A,SMTN,RAB3GAP1,ARHGEF40,BTBD7,SLC22A4,RIMS1,MBD5,SNRPN,MYO16,TRERF1,KIF21B,NMNAT2,MYCBP2,PEG10,ZC3H13,SPTAN1,IQSEC2,TSPYL2,RBM26,TAB2,NXT2,NCDN,MPRIP,DIP2A,KANK1,SEPT3,AJAP1,SYT1,COBL,ASTN2,SYT5,ATP11A,TACC1,TACR1,KAZN,IQCE,FBXW11,MGRN1,TCF12,SYNE1,NAT16,USP32P1,GPRIN3,PCDHA5,DNAH7,DICER1-AS1,TIAM1,ZFP91,HEY2,TMOD1,RIMBP2,CSMD1,CHST5,TRH,TSN,ANO5,LRTM2,TTC3,TUB,OSBP2,FLRT2,PLEKHH2,USP1,WIPF1,P2RY12,CLIP2,CLDND1,ZNF540,ZNF70,FMN2,MKRN3,MAP3K12,SLC38A1,PRDM8,SEMA3B,MDH1B,PCDH15,WIPF2,FZD3,MARCH8,PHTF2,FAM219B,JMJD1C,PIANP,FXR1,NETO1,CPNE4,PRRT4" MicroRNA hsa-miR-580:mirSVR_highEffct hsa-miR-580:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.54E-160 1.99E-156 1.46E-158 1.35E-157 421 1808 "SERPINA3,ABAT,KCNH8,CLK4,ARID1A,NDRG3,ADAR,SLC12A5,ERMN,PWWP2A,PTCHD1,DPY19L2P4,SLC44A5,MTUS1,GPR158,OSBPL1A,WDR35,LRRC7,FAM135A,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,UPRT,ALS2,CACHD1,AQP4,ARRB1,NCOA1,NUMB,TMEM108,ATP1B3,ATP2A2,ATP2B1,ZNF583,RGS9,ARHGEF7,NAE1,SCAPER,BTRC,CA8,CACNA1D,CACNA1E,LURAP1,KALRN,CAST,CH25H,SPAG9,RUNX1T1,TMEM257,SYNGR3,CD38,C1orf52,SEPT7,CDC42,ZMYM4,LGI1,CCPG1,COPB2,SYNPR,NDST3,CLTB,C4orf33,LY86,NIPBL,CNN3,COL11A2,TBPL1,BAG4,ACBD5,MYRIP,ZFP28,MFSD4A,HS3ST5,FAM171B,CLOCK,PREPL,AKAP12,TRIM69,ARHGEF10,CSNK1G3,ATRNL1,PDE4DIP,ERC2,UBXN2A,PHF14,PNPLA8,CTH,GREB1,NRSN1,PUM1,ST18,DCAF4,USP6NL,CCDC144A,HDAC9,KATNAL2,HDAC4,ZFYVE16,MAML1,DAPK1,AIF1L,MYEF2,FBXL5,GUCD1,RHOBTB1,RABGAP1L,WDR20,DLG4,DMD,CASP8AP2,ACOT8,ABI1,PDCD6IP,ECM2,EDIL3,HIPK3,FCF1,SYT15,FRY,FSD1L,PHF20L1,MBNL2,PLEKHA1,RGS17,DCTN4,TUBD1,EPB41,EPB41L2,KCNMB2,DENND4A,CEP85L,CDHR1,MRPL37,TMEM74,ETV1,DNAJC27,EXTL2,ZNF461,SH3YL1,TUBA1B,SCML2,FDFT1,ZNF589,FER,FGF14,POLK,SCARA3,SEC23B,NBEA,TACC2,TMEM107,SMC2,ATP6V1H,ATP2C1,ZNF605,ERGIC3,DKK3,GABRA1,GABRB3,GALC,ARPP21,ERAP1,DISC1,LRRC37A6P,GATM,SULT1C4,PCDH17,GGTA1P,PPARGC1A,LYVE1,DBF4,PCDH11X,KDM2B,INSM2,ZNF782,PRUNE2,EML4,PCLO,GRM5,RNF165,MAP4K5,GYG1,C1orf94,HNF4G,HNMT,HSF2,HTR2A,MSL1,ZNF181,ZNF546,C2orf72,IGFBP1,LIX1,ZNF678,LRRTM3,ITGAV,JAK1,SLC35G1,KIF5A,LINC00634,LIMS1,SYTL4,HECTD2,NCOA7,MAG,MAP4,MARK3,SHC3,MIA2,XRRA1,MOBP,ZNF680,MRPL42,MSR1,NRBP2,LAYN,NAP1L1,NCAM1,NEK1,NF1,OTOGL,NPPA,NTRK2,GPR88,OPHN1,P2RY1,PBX1,DPY19L2P2,PCSK1,PDE1A,PDE4B,PDGFRA,BEST3,OLA1,CDK14,NALCN,ANLN,FAM216A,PLCL1,PCDH18,HMGCLL1,PURG,TRHDE,ING3,MED1,PPP2R5C,PPP3CA,PKIA,RAB39A,MASP1,SIDT1,CNTLN,PTK2,PTPRD,NKAIN1,USP47,SH3TC2,FAT4,ENOX1,OXR1,SLC6A15,ZYG11B,ZMAT4,RFX3,TTLL7,MRPS18A,SEC61A2,SLC25A36,RIC8B,PBRM1,ZFHX4,CCDC82,ALG9,ROBO1,ROBO2,RORB,CCDC102B,RPE,ARMH4,UEVLD,SPIN3,ZC3H14,MCMBP,GLDN,LRRK2,ABCA11P,ATAT1,ZNF354C,ZNF568,RYR1,AP1AR,DGLUCY,SATB1,SCN2A,LRRTM4,SCN8A,LINC00461,SCP2,FNIP1,SLC30A10,SUPT20H,TRA2B,KIF21A,SH3GL3,KIF16B,CPEB3,CHD9,FHOD3,CCDC92,NLGN1,CTXN2,SEC31A,ANKRD6,ZNF365,SLC1A6,PPP4R3A,SLC6A1,SEPHS1,SLC9A5,SLC12A2,NAPB,SLC15A2,ATF7IP,SPHKAP,TET1,CDK5RAP2,ANKRD36,SNCA,CMTR2,SNRPN,UNC80,TRERF1,SOX2,SOX5,BDP1,ENKUR,KDM4C,PEG10,RBM26,NPAS3,SPART,NFASC,TAB2,CLASP2,CLSTN2,NXT2,STAU1,ZSCAN29,NEK4,RGL1,DIP2A,ADHFE1,KANK1,NECAB1,ZC3H4,PRRC2C,VPS13A,NUDT10,SYPL1,TAC1,TAC3,CAMSAP2,UNC5D,ADGRL3,ANO4,TCF7L2,ZEB1,WASHC4,WDR7,RALYL,PCDHB10,AKNA,FRYL,SIK3,TIAM1,ERCC6L2,FAM124A,KAT6B,CDK20,SYNPO2,TRO,TMEFF2,CADM1,UBE2H,AMOT,UGT8,SLAIN1,PLEKHH2,MEAF6,WIPF1,NSD2,GUSBP1,PCDH20,ZNF711,ZNF19,KCNT2,CFAP52,FMN2,ZNF138,REEP1,TMEM237,MEIS3,UPF3A,EMSY,PRTFDC1,LINC02210,STOX2,KCNAB1,FAM47E,PCBP4,MPPE1,WNK3,EPM2A,GOPC,ST7,HNRNPA3,FRMD6,NETO2,SLC4A10,ZNF30,SENP7" MicroRNA hsa-miR-182:mirSVR_highEffct hsa-miR-182:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.10E-160 3.42E-156 2.50E-158 2.30E-157 400 1636 "SDE2,AS3MT,SYS1,ADCY2,ADCY6,ADD3,ADORA2A,PTCHD1,ADRA1D,KIDINS220,DPY19L2P4,SLC44A5,GPR158,SNX32,WDR35,ADGRF5,LRRC7,ABCD2,FAM135A,ALK,PDZD4,OGT,CDC42BPA,DPP10,ANK3,MAP4K3,APBA2,APC,GPAM,LGR5,ARHGDIA,ARNTL,RGS20,CADPS,LINC00173,ASPH,NCOA1,NUMB,ATP1A2,ATP1B3,ADGRB3,SEC11C,BMPR1B,DST,SYNJ2,ARHGEF7,JAZF1,CA8,CACNA1E,CACNB2,CACNB4,CALB1,SYT6,ISPD,SPAG9,RUNX1T1,ARHGEF1,SYNGR3,LRBA,ARHGEF2,SEPT7,ZMYM4,LRRFIP1,LGI1,MAGI1,FOXN3,SOCS6,CHRNA4,NDST3,TJP2,QKI,MAP4K4,NIPBL,CNN3,AKAP7,ARMC8,SLC25A27,AKAP5,SLC4A8,BAG4,MYRIP,ZFP28,IGDCC3,CHD1L,SLC35F1,CLOCK,PREPL,CREB5,TRIM69,AATK,LRIG1,MICAL2,CSNK1G3,SOCS5,DZIP3,ERC2,NRSN1,USP6NL,HDAC9,FGFR1OP2,TMEM170A,TOMM20,C8orf34,ZBTB24,ELMO1,HP1BP3,DDX46,RHOBTB1,SACS,DLG2,DMPK,DNAH9,DYNC1I1,NR1D2,PDCD6IP,DSCAM,DNAJB6,E2F5,AASDH,EBF1,SEZ6L2,EDN1,EDNRB,FCF1,RASGRP1,OPTN,YAF2,FAM13A,PHF20L1,MBNL2,EGR3,AASS,TENM1,ELAVL2,RGS17,C8orf37,USPL1,EPHB1,KCNMB2,NCALD,IGSF6,MRPL37,VPS26C,EXTL2,EZH1,NRN1,CEP78,GORAB,FGF1,FOXF2,SYNCRIP,COQ5,FAM49B,KHDRBS3,AP4B1,NRG3,MEGF11,GABRA1,CHL1,AHCYL1,NCKAP1,SIGLEC8,SEPT9,SULT1C4,GK,GLI2,TOX3,KDM2B,PRUNE2,ATF7,LILRA1,PRLHR,GPR22,LPAR4,NUDT21,EML4,GRM1,GRM7,HAS2,C1orf94,KLF12,ARHGAP36,ELOVL5,ACOT7,ZDHHC15,LRRC75A,EID2B,IRF8,IDH3B,C2orf72,SOWAHA,SLC35G1,KCNJ5,KCNJ16,KCNK2,KCNMA1,KCNN3,STXBP5,KTN1,L1CAM,LIMS1,HECTD2,ASPRV1,SMAD1,PIK3AP1,MAP6,MARK3,MATN3,LRP1B,MEF2C,MEIS2,MIA2,MITF,WDR49,SAMD5,TAGLN3,MYH6,PABPC1L2A,NAP1L1,NASP,NDP,NELL1,NF1,OTOGL,DNHD1,NPTX1,SLC11A2,NRCAM,HCN1,IGSF11,OCRL,CHAMP1,OMG,PAK3,PC,PCDH8,PCMT1,PDE1A,PDE4D,PDGFRA,GPR173,GPR85,BEST3,PFKFB3,ABCB1,NALCN,ANLN,ZNF655,FAM218A,A2ML1,RETREG1,PCDH18,SMIM7,HMGCLL1,PDZRN4,PMP2,LRP12,SLC36A4,MED1,PPM1B,PRKACB,EPDR1,MAPK9,PRPH,SAMD9,MDGA2,PSMD13,CNTLN,PTCH1,PTHLH,ZSCAN32,OCIAD1,PTPRG,PTPRZ1,TMEM145,CEP97,OXR1,RASGRF2,HKR1,VEPH1,SLC6A15,ZYG11B,ZMAT4,RET,ERI2,GTDC1,RFX4,RPRD1A,TMLHE,ELP2,SNX22,RPL15,FBXW7,SPIN3,PTGR2,SYNDIG1,ABCA11P,ATAT1,KCNIP1,RYR3,SEMA6D,CSRNP3,SCN2A,SOX6,ZFP30,KIF21A,PPM1E,DOCK10,NTNG1,SHC4,CHD9,ABLIM3,SLC1A6,FAM81A,LRRC55,SEPHS1,ATF7IP,LIMCH1,SNCA,SNRPN,PALLD,PDZD2,MYT1L,SOX2,SOX3,HECW1,KDM4C,TEX2,LMO3,STOX1,LARP4,TTBK2,RGL1,ADHFE1,KANK1,ZFR2,TMEM150C,SYPL1,COBL,POPDC3,CAMTA1,CAMSAP2,ADGRL3,FBXW11,SATB2,PCDHGB7,WDR7,DOCK9,RALYL,PCDHB3,DICER1,ITGB3BP,ZMAT3,TGFBR3,TIAM1,ERCC6L2,TMOD1,KAT6B,TNR,TPM2,C9orf85,SYNPO2,DCBLD1,TSN,RFTN2,CADM1,PLEKHH2,BCL2L13,MEAF6,VLDLR,P2RY12,CLDND1,XRCC4,ZIC1,MICU3,GPR158-AS1,MKRN3,TCEAL7,ZNF184,EML6,SPIRE1,DHX33,CA10,CADM2,EVI5,STOX2,ADAMTS9,CIAPIN1,FAM47E,MVB12B,C12orf4,EPM2A,FAM13C,AMN1,FZD3,RTN4,PHTF2,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-105:mirSVR_highEffct hsa-miR-105:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.63E-160 3.72E-156 2.70E-158 2.48E-157 375 1437 "RALGAPA1,ACADM,SLITRK1,ADD2,SORCS1,KIAA1211,KIDINS220,SLC44A5,TXNDC16,SPARCL1,ABCD2,ZNF687,AMPD3,OGT,DPP10,EP400,MAP4K3,PPFIA1,APBA2,GPAM,API5,USP37,SEMA4G,STK33,ASPH,ZBTB10,NCOA1,NUMB,RASL11B,ATP2B1,BACH1,RGS9,BLM,DST,ARHGEF7,SCAPER,MMD2,CALM1,CAMK2G,SLC25A14,VSTM2A,CLDN10,LDB2,KRIT1,USP6,USP2,INA,MYOM2,CDH2,CDH8,ZMYM4,MAGI1,TIGD7,CIART,CFL2,SRSF11,CHN2,SYNPR,RAB3C,SLIT2,NRXN1,NGEF,TJP2,ABCG2,NIPBL,CNN3,IQCK,BTF3L4,COL9A3,ZFP28,CP,CHD1L,PREPL,CREM,ANKRD44,SLITRK5,ARHGEF4,NRSN1,RIPOR2,ARHGAP24,TOX,ZFYVE16,KIF26A,MAML1,PABPC5,GIT2,PITPNC1,DNAJC6,JAKMIP2,HP1BP3,RHOBTB1,SGSM2,WDR20,FAM107B,DLG2,EXOG,GRIN3A,PDCD6IP,ECM2,DNAJB6,GOLT1B,FAM135B,HIPK3,CNNM1,RBM12,YAF2,PHF20L1,MBNL2,EIF4G2,COPS4,PLEKHA1,PAN3,LRRC17,EPHA5,EPHB1,CEP85L,EXTL2,WAC,RPS6KC1,SH3YL1,SCML2,DLC1,FDFT1,TESK2,SEC24B,SPSB4,FGFR1,AMOTL2,FHL1,SYNCRIP,SLC37A3,NBEA,TACC2,HVCN1,UFM1,ATP2C1,CELF1,MSANTD4,AP4B1,STAG2,GABRA2,GABRB1,CAB39,GAD1,GALC,DISC1,KIAA1841,PPARGC1A,MALT1,RND1,TCERG1,COPS8,GLDC,DBF4,SPIN1,GLI2,RAB30,GLS,MSL3,KDM2B,POLL,DCLK2,GNAS,FERMT2,FUT10,LPAR4,PCLO,ATP2B1-AS1,GRIA2,GRIA4,GRID1,PRDM5,BTN2A1,LINC00839,PTPN5,ATG4C,MAEL,HPS5,MIER3,HLF,HMGB1,GABARAPL2,HNRNPK,HSF2,LRRCC1,LIX1,BRINP3,ZNF678,LRRTM3,KCNMA1,KIF2A,KIF5C,KLC1,LAMP2,PAXBP1,SYTL4,FGFBP3,MAP2,MAT2A,LDLRAD3,MEF2C,MITF,AFDN,MPP2,MSR1,MT1M,CTNNA3,MTR,MXI1,MYO9A,FXYD7,NASP,NDUFA5,NEK1,OTOGL,NFE2L2,CNOT4,SLC11A2,NTRK2,NUCB2,CHAMP1,OGG1,OXTR,GPR137C,PBX1,PCDH9,PCMT1,PDE1A,PDE1B,GPR85,GNG2,BEST3,PFKFB4,FAM218A,A2ML1,ST8SIA5,PLCL1,PCDH18,MAPKAP1,EPB41L4B,TNPO2,TATDN3,CRLS1,PPP3CA,PPP3CB,PKIA,PKN2,DIRAS2,RELN,SYTL2,MDGA2,MTMR10,PTHLH,PTN,ZSCAN32,PTPN13,PTPRG,FAM120C,QDPR,RAB5B,CEP97,FAT4,RAP1GDS1,RBBP6,REV3L,GTDC1,RPRD1A,ZNF532,ELP2,CCDC102B,MRAP2,NEK11,ARMH4,ZC3H14,MCMBP,GLDN,ACER3,RPS20,ABCA11P,WLS,CLIP1,FAM182A,FAM19A1,FNIP1,SELL,SFPQ,TRA2B,HKDC1,FNDC3A,SEC31A,PAAF1,SLC8A3,CCDC88A,SLC12A2,ATF7IP,CXXC4,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,SNRPN,UNC80,DOK5,KDM4C,TEX2,KIF1B,RBM26,TROVE2,ITPRID2,ZNF302,NKAIN2,ELOVL4,KLHL7,VPS13A,COBL,C12orf76,ATP11A,PJA1,CAMTA1,EXOC7,CAMSAP2,TBCEL,SIN3B,ZEB1,WASHC4,SZT2,WDR7,NSD1,RNF216P1,ZFPM2,SLC44A1,TIAM1,MTMR14,TJP1,TLL2,HEY2,FAM124A,R3HDM1,TPM1,SYNPO2,AMACR,PPIL6,TTC3,TMEFF2,HIRA,RPL7L1,FAM155A,AMOT,FLRT2,PLEKHH2,XRCC4,ZIC1,ZIC2,ZIC3,ZBTB16,ZNF189,PLPPR5,CA10,EMSY,PRDM2,LRP8,PRDM8,LMAN2L,NAV3,SLC17A6,EPM2A,PAK5,HNRNPA3,SSPN,NETO1,CBLN2,SRGAP2B,SPATA13,SENP7" MicroRNA hsa-miR-150:mirSVR_lowEffct hsa-miR-150:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-159 8.59E-156 6.18E-158 5.69E-157 437 1952 "TTYH1,ASIC1,CLK4,XKR4,NDRG3,KLHL32,ADCY6,RNF157,ADD1,SLC12A5,GRAMD1B,ADORA2A,PTCHD1,MTA3,HACE1,CC2D2A,ALCAM,ARHGAP20,ZFAT,MYH7B,CNTNAP1,APBA2,APBB1,KCNAB2,GPAM,LGR5,ARHGAP5,ARRB2,ASCL1,CAPRIN2,SLC4A4,SLC2A11,N4BP2L1,TTLL9,ADAM15,BACH1,ADGRB3,LINC00847,BMPR1B,ARHGEF7,GPC2,CACNB4,CAMK2G,TRIM41,VXN,PRC1,METTL6,P2RX6,CD86,CDH2,MAGI1,CRLF1,CASC2,MS4A7,ZBED5,C7orf61,ZFYVE9,MYL6B,NMT2,HECTD1,MAP4K4,NIPBL,CNGA3,TMEM155,SUMF2,SLC4A8,AHCTF1,MFSD4A,CHD1L,SNCAIP,RGS6,CSF2RA,FEZ1,OSBPL3,CHD5,GREB1,NRSN1,DOCK4,MYADM,GAPVD1,ARHGAP24,PHF19,KIAA0513,LONRF1,RIMS3,PABPC5,ELMSAN1,ZEB2,C2CD2L,KIAA0319,BLOC1S6,POM121,RHOBTB1,SACS,SV2A,SRGAP3,ARNT2,ZNF582-AS1,DLX1,RPS6KL1,NR1D2,SLC25A18,DSCAM,RCAN1,ARRDC4,MAMLD1,DNAJB6,E2F5,FAM135B,EDNRB,KLHL5,YAF2,GPR61,MRO,TMEM132E,AASS,C8orf37,LRRC23,SEZ6,SRRM1,NCALD,PIPOX,RCSD1,ANKMY1,NSRP1,SCML2,RACK1,TOMM40L,STRADA,TESK2,ZNF589,FGF14,FGFR1,AMOTL2,PRKAG2,POLK,UBE2E3,IP6K2,VTI1B,AGAP2,ATP13A4,NOP56,DCTN2,C2orf88,ZCCHC17,SORBS1,TMEM107,ERGIC3,MSANTD4,SARAF,ZMAT1,GAB1,GABRA2,GABRA3,ARPP21,ERAP1,MTHFD2,C15orf41,CPLX2,MSTN,MMADHC,GGT7,HEPN1,GLDC,RAB30,ZNF638,KDM2B,LUZP2,RAB40B,LILRB4,GRK4,GRIA2,GRIA4,PLPP7,RFFL,SPACA9,GSN,FAM19A2,LINC01551,GUCY1B1,CELF3,WIF1,MAEL,HPS5,GPR45,ZDHHC15,HSD17B1,MSL1,DISP2,PLD5,USP54,ZNF678,INPP5B,ITGAM,ITGAV,ITIH2,SLC35G1,OLFM3,KCNJ10,KCNJ11,KCNN3,LINC00634,KTN1,LSS,MAN2A2,MAP4,MBNL1,AFF1,ZNF680,PTOV1,CTNNA3,MXI1,MYH7,MYO5A,RTL5,NAP1L1,NCAM2,NEFM,NELL2,NEUROD1,NF1,NKX2-2,SLC11A2,SMIM11A,NTRK2,NUCB2,FAM225B,P2RX7,GPR137C,ZDHHC22,PIRT,PDGFRA,GPR85,PFKFB3,CDK14,HERC2P3,DUSP26,NLGN3,NALCN,SEMA5B,PIK3R1,XRN1,SMOX,MAPKAP1,LRP12,TNPO2,NXPH1,POU3F2,POU6F1,PPM1B,PPP2R2B,PTPA,PKN2,MAPK9,APTX,GDPD2,PIGG,PTCH1,PTK2,STK32A,PTPRB,OCIAD1,PTPRN2,PYGM,RIPOR1,CCDC40,FAM66C,RALGDS,C1orf54,ZNF493,DPF2,PRRT2,RGS3,ARHGEF10L,KIF7,KLHL11,PBRM1,RPRD1A,SETD5,EXD2,ARMC5,CARF,ROBO1,RPE65,PGBD4,FBXW7,ZNF671,ADAL,FAM161B,MEG3,HSD11B1L,ST6GALNAC6,CLIP1,FAM192A,HOGA1,SCN2B,SCN8A,TRIM46,GALNT10,FOXRED1,SCAF8,NLGN4Y,ITSN1,PPM1E,ASAP3,NTNG1,FBXO11,FNDC3A,CTXN2,ANKRD6,PPP4R3A,KANSL3,ZNF430,SLC8A3,ARHGEF40,SLC14A1,TET1,CPEB4,ZNF667,SMARCC2,SORCS3,MBD5,SNRPN,TMCC1,UNC80,TNIK,SOX5,ZCCHC24,BDP1,ZSWIM8,ENKUR,GLT8D1,CAND2,TEX2,KIF1B,DDN,NFASC,SSTR2,EPB41L3,ZC4H2,LRRC4,INKA2,ZSCAN29,DIP2A,PHLDB1,AJAP1,NSFL1C,PRRC2C,ZFR2,DNAJC9,TMEM150C,SYN2,POPDC3,TACR1,KAZN,EXOC7,UNC5D,FBXW11,TBX15,TRIM2,WDR7,AKNA,ARHGEF12,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,ATP13A2,DICER1,SIRT1,AP4E1,GPR161,TIAM1,TMEM9,TK2,FAM124A,R3HDM1,KAT6B,ZNF346,STXBP4,ZMYND8,FNDC5,DCBLD1,TMPRSS5,TTTY15,PRR18,CLHC1,RPRM,EIF4ENIF1,PITPNB,USP1,VAV2,VLDLR,TBC1D15,WIPF1,NSD2,RICTOR,ZBTB14,ZNF28,KCNT2,ZNF45,ZNF74,CELF4,ZSCAN26,ZNF189,ZNF213,DHX33,SLC30A4,MAP3K12,PRDM2,DNALI1,LINC02210,XKR7,ADAMTS9,PCDH15,NAV2,KCNAB1,WIPF2,MVB12B,PARP11,PDSS2,FAM13C,KAT6A,SMIM8,HNRNPA3,ZNF248,RNF170,FRMD6,NETO2,AP3B2,SLC4A10,LAS1L" MicroRNA hsa-miR-18a:mirSVR_lowEffct hsa-miR-18a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.56E-159 1.44E-155 1.03E-157 9.47E-157 399 1634 "ASIC1,ADARB2,KLHL32,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,AXIN2,SLC12A5,ESYT2,DPY19L2P4,RTL9,HACE1,KIAA1324,AK2,SEMA6A,USP35,FAM135A,SYT13,DPP10,ANK2,LCORL,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,UPRT,GPAM,NT5C3B,APOC2,AQP6,ARHGAP5,CDK13,NUMB,ASTN1,DDX3Y,CHID1,EIF4G3,DPY19L3,ADGRB2,LINC00847,BBS2,SEC11C,DST,SYNJ1,MYRF,CACNB2,CACNB4,PTBP2,CAMK2G,HIP1R,RHBDL1,NFS1,LDB2,CD86,NEURL1,CCPG1,TAOK2,NRXN3,TPP1,DGCR9,VAX2,SULT4A1,CNR1,ABI3BP,MFSD4A,CP,FAM171B,CLOCK,CRY2,ANKRD44,TENM4,CSF1R,SEC24C,CSNK1E,SIPA1L1,SLITRK5,PHF14,CTH,CTNND2,MYADM,DCAF8,KIAA0513,TBC1D5,KIAA0586,CTIF,GIT2,ZNF804A,DGCR5,MYEF2,CNIH3,TMEM130,BLOC1S6,PLPPR4,SNAP91,SRGAP3,DNM1,DYNC1I1,SLC12A6,ABI1,DYRK1A,ABCC5,ABCC9,E2F5,USH1C,EDNRB,PHC2,EGFR,MBNL2,KMT5B,TNK2,TMEM35A,MFSD10,GPHN,ERBB2,DENND4A,ANKMY1,SIRPB1,F3,TUBB4A,ATP8A1,CHST15,FKTN,ZSCAN30,ZNF589,GORAB,FGFR3,UBE2E3,SYNCRIP,FLT1,PSD2,EFCAB2,NBEA,SMC2,UFM1,STAMBP,CAMKK2,DACH2,B3GAT1,HHIPL1,TPPP3,NRG3,GAB1,GABRB1,GABRB3,GABRG2,NEK6,IP6K3,ZNF559,DISC1,LRRC37A6P,KIAA1841,ALDH1L1,ADAM28,ZNF276,COPS8,SPIN1,GLS,WDFY3-AS2,ADGRA3,GPD1,GPM6A,TDRKH,LILRA1,DIDO1,GRIA4,PLCD4,GRIK3,ADAMTS13,GRM1,ZNF496,RNF165,TMEM25,PTGDR2,PACSIN2,ATXN2L,TNFAIP8L3,MIER3,VSIG4,ELOVL5,HMGB1,HMGCL,AGFG1,DHX35,HTR2A,MSL1,FAM95B1,RBPJ,LRRCC1,IGSF1,METTL21A,KCNA1,KCND2,KCNN2,KIF5C,KIT,IPO5,STXBP5,KTN1,SYTL4,VWA5A,HECTD2,ARHGAP12,ZNF667-AS1,MAP4,MARK1,MAT2A,SYT9,ADAM11,MEF2C,MEIS1,ERICH3,JAKMIP3,SCG3,TAGLN3,CTNNA3,MDGA1,NAP1L1,FXYD6,NCAM1,NEUROD1,NOVA1,NTRK2,NTRK3,NUMA1,OGG1,OLR1,LOC100128398,OPRL1,SNTG1,PAX6,PBX1,PCDH9,CDK18,PIRT,SLC10A4,GNG2,PFKFB2,PFKFB4,PCDH18,C11orf49,ANKRD16,RC3H2,EPB41L4B,POU6F1,PPM1B,PPP2R5E,EPDR1,BCAS3,WBP1L,NCR3LG1,BDNF-AS,PTHLH,TMEM260,ZSCAN32,PTPN13,EML5,PTPRE,PTPRG,PTPRO,FAM120C,PTPRZ1,RAB5B,PID1,CCDC40,SH3TC2,ZCWPW1,ARID4A,REV3L,RGS4,RGS7,RGS12,TTLL7,LGI2,ALG9,GSTCD,ROBO1,KIRREL1,ELP2,PCMTD2,EPHA10,BAALC,SGSM1,ADAL,LRRK2,KCNIP1,CLIP1,FAM182A,FAM192A,FOXRED2,SAFB,SEMA6D,ATXN1,SCP2,SMPD3,TRIM46,SCAF8,PPP1R9A,FERMT1,FNDC3A,CLSTN1,ABLIM3,SLC2A5,LRRC55,SEPHS1,CCDC88A,CPEB4,ARFGAP1,NAXD,MAST1,CDK5RAP2,IFT122,IGSF9B,ANKRD36,SNCA,SNRPN,PALLD,MYO16,WDTC1,ZCCHC24,FNBP1,ZSWIM8,CLUAP1,SRPK2,CLASP2,CLSTN2,POGZ,MESP1,SSTR2,SSPO,ZSCAN29,GSE1,NSFL1C,NECAB1,PLCB1,ARC,SYN2,SYPL1,DNMBP,CAMSAP2,KLHL4,TCF7L2,TRIM2,WDR7,RALYL,FAM189A1,PCDHB4,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,CRB1,TGFBR3,TJP1,ERCC6L2,TMPO,CSMD1,CABIN1,TNS1,RBFOX2,TPM2,TPM3,WBP2,CHST5,UBE2H,OSBP2,FLRT2,ZNF709,VLDLR,ZIC2,ZNF540,PLPP4,ZNF154,REEP1,POLR3H,PLPPR5,TFIP11,WNK1,RGMA,CSDE1,RNF103,GAL3ST3,PARP11,PDSS2,ST7,UBE3B,TRAM2-AS1,PIANP,SLC4A10,PRRT4" MicroRNA hsa-miR-20b:mirSVR_highEffct hsa-miR-20b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.54E-159 2.55E-155 1.81E-157 1.66E-156 396 1612 "KCNH8,NCKAP5,SORCS1,SLC24A4,HACE1,ABCD2,MRTFA,SEMA7A,USP28,SUGT1P4-STRA6LP-CCDC180,TNRC6C,APP,SHTN1,AQP4,CASK,LINC00173,STK33,CAPRIN2,ASPH,BRINP2,RASL11B,ASTN1,ATP1A2,SLC4A4,EIF4G3,ATP1B3,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,MAP7,CBR1,USP6,C1orf52,TIGD7,CFL2,CASC2,MS4A7,B4GALT6,TAOK2,EPS15L1,ZFYVE9,ABCG2,C4orf33,COL4A5,SLC25A27,AKAP5,SLC4A8,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,TOMM20,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,RABGAP1L,OLIG1,USP3,DMTF1,DPYSL2,DRD1,FAM78B,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,NSG1,MSANTD4,ZNF512,GABBR1,GABRA1,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,DISC1,WASF3,MYOZ2,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,ATP2B1-AS1,GRM7,CIT,LINC00839,TMEM25,AP4S1,RABL2A,IRAK3,HAS2,HPS5,KLF12,HTR5A,MSL1,DOCK7,USP54,ITGAV,JAK1,METTL21A,OLFM3,KCNJ10,KCNJ16,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,NCOA7,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MOG,MSR1,MXI1,MYCN,MYH6,NCF2,SFR1,NELL2,NF1,CNOT4,NTRK3,OCRL,OGG1,OPA1,GPR137C,CNTN3,ETFRF1,PDE3B,PDE4D,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PSAT1,PRRX1,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,TMEM260,PTPN13,PTPRD,PTPRO,RAB5B,CEP97,TMEM255A,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,GTDC1,RFX4,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,ATXN2,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,IQSEC2,ZBTB43,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,RALYL,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,PRMT8,TSC1,TTPA,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,WNK1,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,PCDH15,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-516b*:mirSVR_lowEffct hsa-miR-516b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.64E-159 2.61E-155 1.82E-157 1.68E-156 435 1940 "SERPINA3,ABAT,ASIC1,ACLY,NCKAP5,SYS1,ACTN1,KDM5D,CSMD3,TMEM132B,ADCY2,PLEKHH1,ADORA2A,PTCHD1,MTUS1,RTL9,USP35,ABCD2,ARHGAP20,GOLGA7B,KCNT1,SYT13,CDC42BPA,CNIH2,APBB1,DDO,CACHD1,TNRC6C,SEMA4G,PDE8B,MARCH3,PCDHGB4,NUMB,ATP1B3,ATP2B1,N4BP2L1,ADGRB3,GPR146,CFLAR,AP1M1,CACNA1G,GPC2,LDLRAD4,CACNB4,DIRAS1,CALM1,PTBP2,CAMK2B,TRIM41,SPAG9,P2RX6,LRRFIP1,CDH18,EVI5L,LGI1,NUMBL,CHM,MS4A7,SYNPR,CNOT8,EPS15L1,RAB33A,CLU,NIPBL,CNGA3,TMEM155,AKAP7,IQCK,COL4A5,SUMF2,AKAP5,TBPL1,BAG4,ZNF521,HS3ST5,CP,CHD1L,CREB5,RNF14,NCOR1,GDA,CS,CSF1,CSF1R,CSF2RA,OSBPL3,PDE4DIP,PLXNA4,KIAA0040,APPL1,UBXN2A,CFAP61,RUBCN,ECE2,RIPOR2,DCAF8,TOX,PHF19,TBC1D5,IP6K1,PABPC5,PITPNC1,ZEB2,ELMO1,KLHL3,ZC3H11A,DDX46,RHOBTB1,SMG7,SV2A,SRGAP3,SEC16A,CHRDL1,DLX1,GRIN3A,RAB39B,HS3ST2,SLC12A6,PDCD6IP,GNE,DTNB,ABCC5,GOLT1B,SNX29,EDN1,EDN3,SGK2,HIPK3,TMTC1,EFNB3,KMT5B,COPS4,TNK2,C3orf18,CALCRL,EN2,TUBD1,COQ7,SRRM1,DENND4A,ETV1,RASL12,CEND1,F8,CLVS1,FAM198B,TMEM132C,DLC1,FCGR1A,TOMM40L,FKTN,TESK2,ZNF589,SLC9B2,FGF12,FGF14,TMEM164,SUCO,SYNCRIP,FOXM1,FLT1,SORBS1,SPECC1,UFM1,PDLIM5,STAMBP,TPK1,NSG2,CGREF1,CSPG5,DOT1L,ABLIM2,OGA,FYB1,MEGF11,GABBR1,GABRA1,NEK6,GHDC,TMEM8B,C15orf41,DISC1,LRRC37A6P,KIAA1841,SULT1C4,TXNL4A,COPS8,TNRC6A,PCDH11X,STARD3,GNAO1,GNAS,ATF7,EML4,GPR37,RAPGEF4,GRIA1,DIDO1,GRM7,MAN1B1,HLF,HMGCR,OPALIN,SMAP1,EID2B,GAREM2,PLD5,IL6ST,SLC35G1,KCNA6,KCNN3,CREG2,KIF5A,KIF5C,KIFC3,KPNA5,ASPRV1,GPR155,MAN2A2,MBD1,CHIC1,MEF2C,SCAMP5,MOV10,MPP2,SAMD5,ADAM22,PTOV1,MX1,MYH7,MYL3,MYO5A,ZNF862,NACA,NBL1,RCOR2,NELL1,NODAL,NPTX1,ODF2,PCDHGC3,PCDH8,PCDH9,PCSK2,PDE4A,GPR85,GNG2,PFKFB3,OLA1,GDAP1L1,SNX10,FAM216A,PLCD1,PLP1,ZNF426,PRIMPOL,PNMA3,RC3H2,FAT3,POU3F4,POU6F1,TMEM235,PPP2R2C,PPP3CB,RASGEF1B,PRKCB,EPDR1,GRAMD1C,MASP1,VPS13C,WBP1L,GDPD2,PTCH1,BDNF-AS,MTMR10,PTK2,PTN,PTPRD,FAM120C,TUG1,PPP2R3C,PID1,SH3TC2,ZNF493,RASGRF2,ARID4A,KHDRBS2,BSDC1,RFX4,UBR7,RIC8B,SETD5,ALG9,CARF,GSTCD,CCDC102B,RPE65,NEK11,PRR5L,SYNDIG1,ATAT1,AMER2,ATXN2,ATXN7,FNIP1,GALNT10,ITSN1,FAM102A,NTNG1,URGCP,BTBD3,KANSL3,LRRC55,SLC8A2,SEPHS1,SLC8A1,ARHGEF40,CDK5RAP3,SLC12A2,SLC22A4,NAXD,SLN,COA1,RCOR3,IFT122,ANKRD36,SNCB,SNCA,MBD5,SNRPN,SCN3B,DOP1A,HECW1,ZC3H13,SPART,SRPK2,TAB2,THSD1,ZSCAN29,STAC2,ADHFE1,PHLDB1,SEPT3,AJAP1,SUPT5H,SYNE2,VPS13A,ADAMTS17,PLCB1,SYPL1,DNMBP,UNC5D,WWC1,TMEM136,TCF4,TCF7,TCF7L2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,USP32P1,TNS2,AHCYL2,TEX15,SIK3,CYB561A3,ZFPM2,AP4E1,ZNF106,SLC44A1,GALNT17,ACTR6,TNFRSF1B,TPD52L2,TPM1,RGMB,METTL3,ELP5,TRO,TSN,CA14,ANO5,TUB,UBE2H,UBE3A,PITPNB,OSBP2,ZNF709,MEAF6,WIPF1,LAT2,WRN,XPO1,ZIC1,GPR158-AS1,ZBTB16,PLPPR5,WNK1,CADM2,LINC02210,STOX2,TUBA1A,ADAMTS9,HPS4,NAV3,URM1,FIP1L1,FAM47E,WIPF2,RGS7BP,FAM13C,DOCK8,ST7,UBE3B,CERS6,MSRB3,IFT88,SOCS4,GAN,SRGAP2B,LAS1L" MicroRNA hsa-miR-516a-3p:mirSVR_lowEffct hsa-miR-516a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.64E-159 2.61E-155 1.82E-157 1.68E-156 435 1940 "SERPINA3,ABAT,ASIC1,ACLY,NCKAP5,SYS1,ACTN1,KDM5D,CSMD3,TMEM132B,ADCY2,PLEKHH1,ADORA2A,PTCHD1,MTUS1,RTL9,USP35,ABCD2,ARHGAP20,GOLGA7B,KCNT1,SYT13,CDC42BPA,CNIH2,APBB1,DDO,CACHD1,TNRC6C,SEMA4G,PDE8B,MARCH3,PCDHGB4,NUMB,ATP1B3,ATP2B1,N4BP2L1,ADGRB3,GPR146,CFLAR,AP1M1,CACNA1G,GPC2,LDLRAD4,CACNB4,DIRAS1,CALM1,PTBP2,CAMK2B,TRIM41,SPAG9,P2RX6,LRRFIP1,CDH18,EVI5L,LGI1,NUMBL,CHM,MS4A7,SYNPR,CNOT8,EPS15L1,RAB33A,CLU,NIPBL,CNGA3,TMEM155,AKAP7,IQCK,COL4A5,SUMF2,AKAP5,TBPL1,BAG4,ZNF521,HS3ST5,CP,CHD1L,CREB5,RNF14,NCOR1,GDA,CS,CSF1,CSF1R,CSF2RA,OSBPL3,PDE4DIP,PLXNA4,KIAA0040,APPL1,UBXN2A,CFAP61,RUBCN,ECE2,RIPOR2,DCAF8,TOX,PHF19,TBC1D5,IP6K1,PABPC5,PITPNC1,ZEB2,ELMO1,KLHL3,ZC3H11A,DDX46,RHOBTB1,SMG7,SV2A,SRGAP3,SEC16A,CHRDL1,DLX1,GRIN3A,RAB39B,HS3ST2,SLC12A6,PDCD6IP,GNE,DTNB,ABCC5,GOLT1B,SNX29,EDN1,EDN3,SGK2,HIPK3,TMTC1,EFNB3,KMT5B,COPS4,TNK2,C3orf18,CALCRL,EN2,TUBD1,COQ7,SRRM1,DENND4A,ETV1,RASL12,CEND1,F8,CLVS1,FAM198B,TMEM132C,DLC1,FCGR1A,TOMM40L,FKTN,TESK2,ZNF589,SLC9B2,FGF12,FGF14,TMEM164,SUCO,SYNCRIP,FOXM1,FLT1,SORBS1,SPECC1,UFM1,PDLIM5,STAMBP,TPK1,NSG2,CGREF1,CSPG5,DOT1L,ABLIM2,OGA,FYB1,MEGF11,GABBR1,GABRA1,NEK6,GHDC,TMEM8B,C15orf41,DISC1,LRRC37A6P,KIAA1841,SULT1C4,TXNL4A,COPS8,TNRC6A,PCDH11X,STARD3,GNAO1,GNAS,ATF7,EML4,GPR37,RAPGEF4,GRIA1,DIDO1,GRM7,MAN1B1,HLF,HMGCR,OPALIN,SMAP1,EID2B,GAREM2,PLD5,IL6ST,SLC35G1,KCNA6,KCNN3,CREG2,KIF5A,KIF5C,KIFC3,KPNA5,ASPRV1,GPR155,MAN2A2,MBD1,CHIC1,MEF2C,SCAMP5,MOV10,MPP2,SAMD5,ADAM22,PTOV1,MX1,MYH7,MYL3,MYO5A,ZNF862,NACA,NBL1,RCOR2,NELL1,NODAL,NPTX1,ODF2,PCDHGC3,PCDH8,PCDH9,PCSK2,PDE4A,GPR85,GNG2,PFKFB3,OLA1,GDAP1L1,SNX10,FAM216A,PLCD1,PLP1,ZNF426,PRIMPOL,PNMA3,RC3H2,FAT3,POU3F4,POU6F1,TMEM235,PPP2R2C,PPP3CB,RASGEF1B,PRKCB,EPDR1,GRAMD1C,MASP1,VPS13C,WBP1L,GDPD2,PTCH1,BDNF-AS,MTMR10,PTK2,PTN,PTPRD,FAM120C,TUG1,PPP2R3C,PID1,SH3TC2,ZNF493,RASGRF2,ARID4A,KHDRBS2,BSDC1,RFX4,UBR7,RIC8B,SETD5,ALG9,CARF,GSTCD,CCDC102B,RPE65,NEK11,PRR5L,SYNDIG1,ATAT1,AMER2,ATXN2,ATXN7,FNIP1,GALNT10,ITSN1,FAM102A,NTNG1,URGCP,BTBD3,KANSL3,LRRC55,SLC8A2,SEPHS1,SLC8A1,ARHGEF40,CDK5RAP3,SLC12A2,SLC22A4,NAXD,SLN,COA1,RCOR3,IFT122,ANKRD36,SNCB,SNCA,MBD5,SNRPN,SCN3B,DOP1A,HECW1,ZC3H13,SPART,SRPK2,TAB2,THSD1,ZSCAN29,STAC2,ADHFE1,PHLDB1,SEPT3,AJAP1,SUPT5H,SYNE2,VPS13A,ADAMTS17,PLCB1,SYPL1,DNMBP,UNC5D,WWC1,TMEM136,TCF4,TCF7,TCF7L2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,USP32P1,TNS2,AHCYL2,TEX15,SIK3,CYB561A3,ZFPM2,AP4E1,ZNF106,SLC44A1,GALNT17,ACTR6,TNFRSF1B,TPD52L2,TPM1,RGMB,METTL3,ELP5,TRO,TSN,CA14,ANO5,TUB,UBE2H,UBE3A,PITPNB,OSBP2,ZNF709,MEAF6,WIPF1,LAT2,WRN,XPO1,ZIC1,GPR158-AS1,ZBTB16,PLPPR5,WNK1,CADM2,LINC02210,STOX2,TUBA1A,ADAMTS9,HPS4,NAV3,URM1,FIP1L1,FAM47E,WIPF2,RGS7BP,FAM13C,DOCK8,ST7,UBE3B,CERS6,MSRB3,IFT88,SOCS4,GAN,SRGAP2B,LAS1L" MicroRNA hsa-miR-556-3p:mirSVR_lowEffct hsa-miR-556-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.79E-159 2.69E-155 1.87E-157 1.72E-156 423 1837 "RBM10,NBAT1,KDM5D,CSMD2,ARID1A,XKR4,BEND6,NLGN4X,INTS2,HECW2,KCTD16,WDR35,C1QTNF3,ALAD,ALCAM,BCAR3,ARHGAP20,MARCH4,ZNF687,KIF6,LRCH2,LCORL,MAP4K3,ANXA7,APBB2,APC,UPRT,GPAM,SHTN1,LGR5,AQP4,IGDCC4,TMEFF1,ASPH,NCOA1,ATM,ATP1B3,ATP2B3,ZNF582,CADM3,DOCK11,BCL2L2,SCAPER,MTMR2,GPC2,CACNA1D,CALB1,PTBP2,TRIM41,LDB2,MTMR7,SLC16A4,SCARB1,ENTPD2,SEPT7,REPS2,CDH8,LRRFIP1,MAGI1,DLGAP1,TIGD7,CCPG1,CFL2,SRSF11,MS4A7,LSMEM2,RAB28,NRXN3,PLAA,CLCN4,TJP2,NIPBL,CNN3,ARMC8,AKAP6,FAM171B,SEC31B,CLOCK,SNCAIP,FEZ1,MICAL2,CSNK1E,OSBPL3,PDE4DIP,PHF14,PLCXD3,CTH,ARHGEF4,ZSCAN23,CX3CR1,GAPVD1,FRMPD4,TOX,KIAA0586,GIT2,YTHDC1,DNAJC6,HEPH,TIAM2,HP1BP3,BLOC1S6,FBXO25,SMG7,SACS,SPOCK3,SRGAP3,NTM,RABGAP1L,USP3,NR1D2,CPEB2,DRD1,DNM1L,GOLT1B,E2F6,EDIL3,WDPCP,FAM135B,EDNRB,TMTC1,FRY,YAF2,SH3GLB1,FAM13A,EGR3,ASB3,EIF4G2,TENM1,ELAVL3,RGS17,EML1,STARD3NL,EMX2,VPS13B,EPB41L2,COQ7,LRRC17,KCNMB2,SRRM1,MRPL37,APC2,TMEM74,ETV1,DNAJC27,ADGRV1,EYA1,F5,FAM198B,WAC,ZIC4,EFEMP1,DLC1,FCGR1A,ZNF589,SLC9B2,MEX3B,SEC23B,SYNCRIP,RGPD5,NELFCD,JKAMP,NBEA,TMEM107,SMC2,PDLIM5,ZNF605,SARAF,MEGF10,GABRA2,GABRB3,GABRG1,B4GALNT1,SALL3,ZNF274,GAP43,GATM,SRCAP,SESN1,MALT1,LYVE1,ZNF276,GLI2,TOX3,LUZP2,GNAL,CNDP1,GPM6A,ATF7,LPAR4,GRK4,GRM1,GRM7,KAT7,BVES,SOX21,PSIP1,RNFT2,LINC01102,SCRG1,ZDHHC15,SHISA6,SOWAHA,RBPJ,DOCK7,LRRCC1,IL12A,DIPK1A,TUBB2B,METTL21A,OLFM3,KCNH2,KCNJ16,KCNMA1,KIF5C,KLC1,IPO5,ARHGAP12,MBP,CHIC1,LRP1B,KCTD6,KITLG,XRRA1,MRPL42,MSR1,ZNF92,DDX25,MYCN,NCAM1,NDP,SFR1,NEUROD1,NF1,OTOGL,NFYA,NNAT,CNOT4,NOVA1,DNHD1,IGSF11,CLDN11,GLIPR1L2,ETFRF1,PCDH8,PCMT1,PDE3B,ENPP2,GPR85,PFKFB3,XRN1,MTRF1L,PRIMPOL,PDZRN4,PMP22,TRHDE,LRP12,SCHIP1,POU3F2,LRRN3,CEP41,PRKCB,MAPK10,HYDIN,RELN,MDGA2,CNTLN,PTCH1,ANKHD1,BDNF-AS,PTN,TMEM260,ZSCAN32,PTPN13,PTPRB,PTPRD,FAM120C,PPP2R3C,KHDRBS2,MSANTD2,SLC6A15,GTDC1,RFX3,RFX5,TTLL7,RLBP1,SLC25A36,RIC8B,NUDT11,CCDC82,SETD5,ROBO2,RORB,TMEM100,ARMH4,UEVLD,LRRK2,CNTNAP3,LGR4,ABCA11P,RTN1,CCDC112,TRAPPC13,ATXN7,LRRTM4,SCP2,SOX6,PPP1R9A,KIF16B,DOCK10,NTNG1,FBXO11,SLITRK3,CNKSR2,NLGN1,CLSTN1,WDR37,PPP4R3A,RUFY2,SLC6A1,CCDC88A,SLC9A5,SLC12A2,ZNF334,TMEM132D,CPEB4,SMARCA4,SMARCC2,MYH15,SMARCE1,RCOR3,SNAP25,CMTR2,UNC80,SOX2,MYCBP2,SPP1,ZBTB43,LMO3,SRPK2,SAMSN1,THSD1,ZSCAN29,SEPT8,GSE1,FGD4,NUDT10,PLCB1,COBL,ANKRD28,ATP11A,ANKRD12,MTCL1,TBCEL,MGRN1,ATMIN,ACSL6,TCF4,SIN3B,DMXL2,CUX2,TRIM2,TCF12,SYNE1,TMEM151B,PCDHB9,AKNA,FRYL,TEX15,CYB561A3,FAM200B,PMS2CL,CRB1,C18orf54,ITGB3BP,TIAM1,TLR4,ZFP91,NR2E1,ERCC6L2,DAAM2,CSMD1,TP53BP2,TPM3,TPM4,CHST5,NR2C2,TRPC1,TRPS1,DCBLD1,TTTY15,TMEFF2,HIRA,ZNF610,AMOT,PLEKHH2,CCDC14,WRN,ETNPPL,ZIC3,MKRN3,TCEAL7,ZNF138,CELF4,ZBTB38,ZNF177,FSTL5,ANKS1B,FTSJ1,PLPPR5,INTS3,SLC38A1,LINC02210,FIP1L1,TMEM163,FAM47E,SLC17A6,AMN1,FZD3,DOCK8,PHTF2,ACTR3B,ADAMTSL3,SLC39A12" MicroRNA hsa-miR-218-2*:mirSVR_lowEffct hsa-miR-218-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-158 6.03E-155 4.16E-157 3.83E-156 415 1773 "CPNE2,ASIC1,SYS1,CSMD2,BRAP,SORCS1,PLEKHH1,KIAA1211,ESYT2,BEND6,SLC24A4,AGT,HACE1,OSBPL6,OSBPL8,CC2D2A,HFM1,LRRC7,ALCAM,ARHGAP20,DPP10,ANK3,CCDC146,MAP4K3,UPRT,BCAS1,CADPS,PCDHGB4,ATM,ATP1B3,ATP2A2,ZNF583,TTLL9,RGS9,DCAF5,KSR1,CDK5R1,SCAPER,IL33,CALB1,CALM1,KALRN,HAP1,CANX,VSTM2A,CH25H,SPAG9,MAP7,RUNX1T1,KRIT1,CCNH,MTMR7,CBFA2T2,TMEM257,CDK11B,ZBED1,CDC42,CDH2,DLGAP1,NUMBL,FOXN3,CHN1,CASC2,KMT2C,PLAA,PPT2,CLCN3,NRXN1,NGEF,ABCG2,SRP14-AS1,IGLON5,IQCK,FAM149A,LETMD1,AKAP5,MYRIP,SLC35F1,ENTPD4,RBM39,LRIG1,FEZ2,FEZ1,ARHGEF10,CSNK1E,ATRNL1,SIPA1L1,VAC14-AS1,PDE4DIP,PLXNA4,SLITRK5,PLCXD3,PNPLA8,CFAP61,PUM1,USP6NL,KIAA0408,ARHGAP32,GAPVD1,ZNF337,KCTD8,SCRN1,ARMCX4,JAKMIP2,DGCR5,CEP170,LYPD1,SPOCK3,MTX3,FAM107B,CCDC3,KBTBD11,ZNF582-AS1,DLG2,EXOG,GRIN3A,USP3,DMTF1,DPH1,CASP8AP2,ABI1,PDCD6IP,RCAN1,DTNA,DNAJB6,FARSB,E2F5,EDN1,FAM135B,FCF1,TMTC1,PHF20L1,SORBS3,ELAVL2,ELAVL3,ELAVL4,ELN,USPL1,EPB41L1,MTSS1L,GPHN,ZNF549,SRARP,DUSP27,ANKMY1,ADGRV1,MRVI1,CLVS1,NSRP1,ZNF461,EFEMP1,ATP8A1,SLC9B2,SUCO,PCYOX1,PSD2,C2orf88,NBEA,SMC2,SPECC1,STAMBP,CELF1,DACH2,CSPG5,ZNF512,GABRB1,GAD1,HBS1L,RAPGEF6,KIAA1841,CPLX1,GATM,LYVE1,BRD8,SPIN1,TOX3,TNRC6A,ZNF638,CBX1,KCNMB4,ATF7,PCLO,GRIA4,GRID1,GRIK3,GRIN2D,NR3C1,RNF165,GSTM5,MUM1,FRMD5,ARHGAP19,LINC01102,HLF,TLX1,RBPJ,USP54,IL6R,ITIH2,KCNJ3,KCNJ5,KCNJ10,KCNK1,KCNK2,CREG2,KIF5C,KIT,STXBP5,STMN1,MAP2,AQP11,MATN3,SYT9,LRP1B,KCTD6,AFF1,AFDN,MOBP,CD200,SAMD5,ADAM22,NRBP2,MXI1,MYO6,MYO9A,HNRNPM,ZC3H12B,NEUROD1,NME4,NOS1,SETD4,OCRL,ODF2,CHAMP1,CLDN11,GLIPR1L2,PAK3,PAX6,PCDHGC3,PCMT1,PCSK1,PCSK5,PDE4D,PFKFB3,ABCB1,PIK3C2A,HMGCLL1,PLXNB3,ANKRD16,PMP2,LRP12,SCHIP1,ING3,SPATA6,PPP2R5E,PRKACB,PKIA,PKN2,PRPH,GDPD2,PLPPR1,ZIK1,PTPRB,PTPRD,FAM120C,RAD51D,RALGDS,RAP1GDS1,ZNF493,REV3L,ERI2,GTDC1,TTLL7,KIF7,RNF220,SLC25A36,LGI2,CCDC82,CARF,ROBO1,TMEM100,SPIN3,ZNF671,MCMBP,LRRK2,ABCA11P,KCNIP3,RTKN,ZNF568,SCN2B,PRCD,SCP2,SMPD3,ELMOD1,IL17RB,SUPT20H,ITSN1,PPM1E,FBXO11,CNKSR2,NLGN1,DZIP1,SLC1A3,SLC6A1,KANSL3,PKNOX2,SLC6A11,RAB3GAP1,SLC8A3,SLC12A2,ATF7IP,ZNF667,SMARCD3,PALLD,PDZRN3,SON,SOX2,BDP1,KDM3A,ZC3H13,BEX1,KIF1B,CDK19,SPART,SRPK2,POGZ,ITPRID2,SSTR2,ZSCAN29,SULF2,GANAB,SEPT3,SYT11,RHBDL3,SYT5,TACR1,DDHD2,CAMTA1,TBL1X,TBX15,VWA3A,ZFP90,CUX2,TCF7,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RNF216P1,DICER1-AS1,AP4E1,ZNF106,THBS4,ARL10,MTMR14,TJP1,TK2,BHLHB9,ERCC6L2,KAT6B,TPD52,TPM2,ZNF384,ELP5,STXBP4,PPIL6,NTSR2,TSC1,ZKSCAN5,RPL7L1,EIF4ENIF1,UBE2H,SLAIN1,OSBP2,USP1,TBC1D15,LAT2,NSD2,ZBTB14,ZIC1,ZNF24,KCNT2,AGMO,FMN2,LYPD6,ZNF177,EML6,ZNF189,UPF3A,SLC30A4,PMEPA1,SLC38A1,CSDE1,LINC02210,ADAMTS9,SEMA3B,PARP11,UBE3B,PAK5,HNRNPA3,FBXO36,FAM219B,RSPRY1,DPF3,SLC4A10" MicroRNA hsa-miR-200a*:mirSVR_lowEffct hsa-miR-200a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-158 6.26E-155 4.29E-157 3.95E-156 406 1698 "VWA5B2,CLK4,CSMD2,ARID1A,CSMD3,KLRC4,CDC7,SORCS1,PWWP2A,PTCHD1,BEND6,DPY19L2P4,NLGN4X,SLC44A5,INTS2,HECW2,AK2,LRRC7,SEMA6A,ALCAM,SRPX,PCDH10,AMPH,ZFAT,ANK3,CCDC146,PPFIA1,PARG,APC,DGKZ,AQP4,PPP4R4,TMEFF1,ARNTL,ASCL1,MARCH3,ASPH,PCDHGB4,NUMB,INSYN2B,ATM,ATP2B2,RNF182,ATP6V1G2,ADGRB3,SEC11C,BCL2L2,NRP2,SYNJ1,ARHGEF7,FUBP1,MTMR3,RAB29,CACNB2,PTBP2,VXN,CAST,CD38,DCLK1,LRRFIP1,MAGI1,CCPG1,NUMBL,NDST3,PLAA,CLCN4,CLU,C4orf33,ARMC8,FAM149A,COL4A5,SUMF2,TOGARAM2,ZNF521,CPS1,CLOCK,RBM39,SLC32A1,ANKRD44,GDA,TRIM69,CS,SNCAIP,LRRC3B,CSNK1G3,ATRNL1,VCAN,APPL1,PNPLA8,CFAP61,PUM1,CCDC144A,ZNF337,TMEM170A,DNAL1,MFAP3L,CEP170,KLHL3,BLOC1S6,SPOCK3,KBTBD11,CHRDL1,DLG2,DMD,USP3,NR1D2,ATN1,PDCD6IP,DTNA,DNAJB6,EDNRB,ATL1,FCF1,KLHL5,FSD1L,YAF2,PHF20L1,SUGP2,ABI2,PLEKHA1,EML1,TUBD1,EPB41L1,EPS8,F3,ABCA8,ACSL4,EFEMP1,ATP8A1,CEP78,PRMT5,FER,FGF1,FGF12,FGF14,CAP2,IP6K2,SYNCRIP,IQCG,SEMA4D,FLT1,SLC37A3,NELFCD,TMEM107,UFM1,PDLIM5,ATP2C1,CELF1,NSG1,MEGF10,GAB1,GAD1,AHCYL1,ZMYND11,SIGLEC8,C15orf41,DNER,GATM,FAXC,TUBGCP4,SESN1,FREM1,PCDH17,PPARGC1A,GK,TCERG1,TOX3,PCDH11X,GPM6A,GPM6B,PRLHR,GRB10,GRIA1,GRIA2,DIDO1,GRIK2,GRM1,GRM7,KIF3A,BVES,AP4S1,PSIP1,GUCY1B1,GYG1,HAS2,HNRNPK,ZDHHC15,NEGR1,SMAP1,HTR2A,IRF8,MSL1,ZIC5,IL6ST,ZNF385B,JAK2,METTL21A,KCNA4,KCNC2,KCNN2,LAMP2,PAXBP1,SYTL4,ARHGAP12,LOC100128239,MAN2A2,MAPT,MBP,TM6SF1,SHC3,MEIS1,POC1B,SESN3,CCDC80,MSI1,ADAM22,MTTP,MYO9A,RTL5,NF1,NFIA,NRCAM,NTRK2,NTRK3,GPR137C,CNTN3,PAX6,PCDHGC3,PCDH8,PCDH9,PDE3B,PDE4B,CYTL1,FAM98B,HERC2P3,SERPINI1,ANLN,ZFYVE21,FAM216A,JAKMIP1,FTO,HMGCLL1,PURG,PMP22,STRN3,LRP12,SCHIP1,PPARA,MINDY2,TATDN3,PRKAB2,PRKACB,KLK6,VPS13C,WBP1L,SYTL2,SNRK,ANKHD1,UHRF1BP1,ZIK1,PTPRE,ZNF615,TMEM255A,FAT4,ARID4A,DBX2,KHDRBS2,TRIM68,RGS3,TTLL7,RIC8B,ZFHX4,CCDC82,EXD2,RAVER2,RORB,ELP2,RPL15,BAALC,ATP8B4,SGSM1,STK32B,KCNIP2,CLIP1,FAM182A,TRAPPC13,DGLUCY,SEMA6D,ATXN7,PRCD,TNFRSF19,ELMOD1,IL17RB,SOX6,CASC3,GALNT10,SFPQ,NLGN4Y,ZFP30,KIF21A,PPM1E,ARX,R3HDM2,SLITRK3,NLGN1,SLC1A3,LRRC55,RADIL,RAB3GAP1,CCDC88A,TMEM132D,ELMO2,SLCO1A2,SLIT1,COA1,ANKRD36,SNAP25,PDZRN3,MYT1L,KIF21B,FNBP1,SOX11,NMNAT2,COLGALT2,SAMSN1,ELOVL4,CEP68,SEPT3,SYNE2,NUDT10,PLCB1,SYPL1,SYT1,COBL,TAF9,TAL1,FAM208A,CNTN2,ADGRL3,TBCEL,EHBP1,SATB2,ZEB1,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,RALYL,USP32P1,TEX15,FAM200B,SIRT1,C18orf54,AKTIP,TLL2,ERCC6L2,DAAM2,NPL,RGMB,SYNPO2,STXBP4,TRPC1,TRPC3,FNDC5,TMEFF2,UCHL1,SLAIN1,FLRT2,MEAF6,CCDC14,VLDLR,RBFOX3,PCDH20,ZNF711,LYPD6,ZNF154,TMEM237,WNK1,CADM2,PRDM2,TMEM178A,PCDH15,FIP1L1,RGS7BP,GOPC,DNAH10,FAM13C,SMIM8,SSPN,CBLN2,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-505:mirSVR_lowEffct hsa-miR-505:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-158 9.20E-155 6.26E-157 5.76E-156 407 1708 "SDE2,SYN3,ADCY2,ADD3,SNX30,PTCHD1,BEND6,OSBPL8,TXNDC16,LRRC7,GPRASP2,ANK3,MAP4K3,ANXA7,APBB2,USP37,AQP4,SLC7A14,ARNTL,STK33,DDX3Y,TMEM108,RNF182,LINC00847,SEC11C,SYNJ2,ARHGEF7,LINC00906,BSN,BTRC,CACNB4,CALM1,KALRN,HAP1,PTBP2,CANX,VSTM2A,CAST,ZNF501,KRIT1,TMEM257,CDC42,CDH8,LGI1,NUMBL,CNOT8,TAOK2,NDST3,NRXN1,NMT2,CLTA,ABCG2,AKAP7,ARMC8,SLC4A8,COX4I1,AHCTF1,RBM39,CRY2,LRIG1,MICAL2,ATRNL1,SOCS5,ERC2,PNPLA8,ECE2,KIAA0408,GPRASP1,ARHGAP32,ARHGAP24,FRMPD4,PHF19,EARS2,ZNF337,KIAA0586,SPOCK2,GIT2,JAKMIP2,C8orf34,KIAA0753,CEP170,FBXO25,GSDME,RHOBTB1,SACS,SV2B,CHRDL1,DLG2,HS3ST4,NR1D2,SLC12A6,DRD1,DNM1L,E2F6,EDNRA,HIPK3,SYT15,SH3GLB1,EFNB3,MRO,MBNL2,TENM1,ELAVL2,ELAVL4,ELN,CALCRL,DCTN4,OLIG2,RABEPK,DENND4A,CEP85L,SPEG,PIPOX,DNAJC27,KATNAL1,EYA1,F3,FAM198B,WAC,ACSL4,ATP8A1,FKTN,TESK2,KAT8,GORAB,SEC24B,KIAA1109,OLFM1,TMEM164,RGPD5,FOXO3,TRMO,TACC2,SORBS1,UFM1,CAMKK2,KHDRBS3,NSG2,ST6GALNAC3,STAU2,DOT1L,NRG3,GABRA5,HBS1L,BRPF3,RAPGEF6,ARPP21,GALR1,NCKAP1,C15orf41,ATP8A2,GATM,CYP46A1,NFU1,GHR,RUNDC3A,TXNL4A,KDM2B,GNAO1,GNAS,ZNF782,GPT2,GOLGB1,PRUNE2,ATF7,GPER1,NUDT21,PCLO,GRB10,DIDO1,GRM7,GRM8,FAM19A2,COQ10A,TMEM25,ZBTB49,GUCY1B1,ATOH8,ZHX1,FRMD3,SYNPO,HNMT,CFAP126,HSF2,RBPJ,HES5,INSM1,NME9,SLC35G1,KCNA1,KCNA2,KCNJ9,KCNJ16,GATD1,KLC1,STXBP5,LAMP2,VWA5A,ARHGAP12,C2orf80,PIK3AP1,MAOB,MAP4,LYPLAL1,AQP11,MATN2,MBP,LDLRAD3,MOBP,ERICH3,JAKMIP3,DDX25,NEXMIF,NEFM,NELL1,NEK1,NF1,SLCO1C1,NODAL,CNOT4,NOVA2,NRCAM,OCRL,GPR88,OPA1,OPHN1,OXTR,P2RX7,PCDH8,PDE4B,GPR85,PFKFB4,NLGN3,GDAP1L1,CCSER2,PLCL1,PURG,PMP2,TRHDE,STRN3,RETREG2,FA2H,NXPH1,PPARA,CCDC144B,PPP2R5E,PRKCB,WBP1L,SNRK,MDGA2,PLPPR1,PTHLH,TMEM260,PTPRE,PTPRG,FAM120C,PEX5,TTC13,TUG1,USP47,ACSS3,RAD17,PLEKHB2,OXR1,ARID4A,ZDHHC14,REV3L,GTDC1,RFX3,ZDHHC4,SEC61A2,PBRM1,RPRD1A,LGI2,CCDC82,ZNF532,ARMC5,ROBO1,SPIN3,ZNF671,PRR5L,TCP11L1,CNTNAP3,PTGR2,ATAT1,KCNIP2,NCBP3,SEMA6D,ATXN2,SCN2A,SCNN1D,ELMOD1,SOX6,GALNT10,FOXRED1,SGK1,FAM102A,NTNG1,MAGI3,CTXN2,WDR37,ZNF365,SLC1A7,KANSL3,SEPHS1,CCDC88A,BTBD7,ATF7IP,EPC1,NAXD,COA1,RCOR3,IFT122,LIMCH1,RIMS1,FAM126B,UNC80,TRERF1,SOX5,ZCCHC24,BDP1,TSNAXIP1,ZSWIM8,NPAS3,RAP1GAP2,NFASC,C11orf87,PBLD,TROVE2,ITPRID2,SAMSN1,ZC4H2,LRRC4,INKA2,MPRIP,ELOVL4,SEPT8,TTBK2,NSFL1C,SYNE2,C3orf70,SYPL1,COBL,KAZN,DNMBP,TAL1,ADGRL3,AGTPBP1,DMXL2,SATB2,ZFP90,TCF7L2,ZEB1,TRIM2,SZT2,WDR7,RALYL,FAM189A1,SIK3,C18orf54,ARL10,HEY1,DAAM2,R3HDM1,CABIN1,TP53BP1,RBFOX2,TPD52,C9orf85,DOK6,AMACR,TRPS1,TTTY15,TUB,FAM155A,PITPNB,ZNF709,CCDC14,VLDLR,ZIC1,ZIC2,ZNF45,FMN2,ZNF74,REEP1,TMEM237,ANKS1B,PCBP1-AS1,SMARCAD1,SYNC,PMEPA1,EMSY,CADM2,SLC38A1,RNF103,PARP11,EPM2A,DOCK8,ST7,PAK5,JMJD1C,NLRP3,ZNF248,RNF170,MSRB3,RNF146,CPNE4" MicroRNA hsa-let-7i:mirSVR_lowEffct hsa-let-7i:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-158 1.11E-154 7.48E-157 6.89E-156 435 1947 "GALNT16,GALNT13,SLC12A5,SORCS1,ERMN,PLEKHH1,UNC5A,OLMALINC,AP2A2,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,FAM135A,MRTFA,BEGAIN,CDC42BPA,ANK1,ANK2,ANK3,LCORL,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM15,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,GPR37L1,ASIC3,MS4A7,CNOT8,TPP1,CLTA,ABCG2,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,SPATA2,DCT,ZBTB24,MED24,BLOC1S6,DDX46,PLPPR4,SNAP91,RABGAP1L,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,FAM57B,PDCD6IP,DSCAM,ARRDC4,DTNA,ECM2,DNAJB6,DYRK1A,ABCC9,SNX29,EDNRB,ANKRD46,CNNM1,YAF2,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,EPB41L2,COQ7,EPHB1,ANKRD13B,RABEPK,CDHR1,KATNAL1,GMPR2,EZH1,F3,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,RACK1,TOMM40L,GTF2IRD2,HPCAL4,CAP2,IP6K2,FLT1,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,ZMAT1,HRASLS5,ZNF234,SIGLEC8,ATP8A2,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,RABL2A,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,ZDHHC15,OPALIN,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,IL11RA,INPP5B,ZNF385B,SLC35G1,CDH20,KCNC1,KCND1,KCNJ10,LAMP2,SYTL4,HECTD2,NCOA7,MAN2A2,MAP4,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,MYCN,PABPC1L2A,NDUFA5,SFR1,NEFM,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,ZNF655,PLCB2,PLP1,HMGCLL1,TRHDE,MAPKAP1,SCHIP1,RANBP3L,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,UHRF1BP1,TMEM260,ZIK1,PTPRD,CASTOR1,PTPRG,FAM120C,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,GAL3ST4,SLC6A15,TRIM68,KCTD17,RIT2,DCUN1D2,EXD2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,UEVLD,SPIN3,KIAA0895L,PRR5L,ACER3,TCP11L1,PTGR2,MEG3,RTKN,TRAPPC13,ATXN2,HOGA1,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,GALNT10,FOXRED1,MRAS,HSPA4L,ITSN1,CPEB3,CTXN2,WDR37,SLC1A7,BTBD3,EPN2,FAM214B,SLC6A1,KANSL3,KDM4D,SLC8A2,ATF7IP,SLCO1A2,CPEB4,MAST1,MYH15,IFT122,INAVA,RBM34,USP33,FAM219A,DOP1A,TNIK,SPATA7,KDM3A,ZSWIM8,NMNAT2,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,TAB2,POGZ,SSTR2,ST5,SYT11,MLC1,FNDC9,PLCB1,TAC1,MMS19,PDLIM2,FBXW11,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,DICER1-AS1,AP4E1,FBXL16,ARL10,TK2,DAAM2,KCTD2,TNFRSF1B,C5orf64,NPL,C9orf85,WBP2,CHST5,RGMB,SMUG1,TRIO,TRO,STXBP4,TRPC3,TSC1,ANO5,TTTY15,PRR18,CLHC1,SLC35A4,AMOT,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF708,MICU3,ZNF28,ZBTB38,ZBTB16,MEIS3,WNK1,LRP8,CSDE1,LINC02210,SIGLEC10,FIP1L1,TRIM16L,FBXO36,CASC15,NUP214,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-338-3p:mirSVR_lowEffct hsa-miR-338-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.80E-158 1.57E-154 1.05E-156 9.71E-156 431 1914 "KCNH8,RBM10,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,PLEKHH1,USP31,UNC5A,ADRB2,AP2A2,KLHL13,OSBPL1A,SMIM17,SEMA6A,ALCAM,SRPX,MARCH4,GPRASP2,PDZD4,AMPD2,AMPD3,SUGT1P4-STRA6LP-CCDC180,APBA2,APC,ALS2,SHTN1,LGR5,SFMBT2,IGDCC4,ZFYVE28,ARNTL,RGS20,LINC00173,CDK13,ASPH,DACT3,NUMB,ASTN1,DDX3Y,SLC2A11,CADM3,N4BP2L1,DPY19L3,DOCK11,BBS2,RGS9,KSR1,GYG2,CFAP410,CACNA1E,CACNA2D1,CACNB4,PTBP2,CANX,VXN,CH25H,RUNX1T1,KRIT1,USP6,CD86,REPS2,CDC42,L3MBTL4,NUMBL,SRSF11,ASIC3,CHRNA4,B4GALT6,KIAA1549L,NRXN1,SULT4A1,HECTD1,NIPBL,CNR1,FAM149A,BTF3L4,ABI3BP,TBPL1,COX4I1,MFSD4A,CRMP1,NCOR1,GDA,CRYM,MICAL2,PDE4DIP,CNTNAP2,DZIP3,PPP1R16B,KIAA0040,PPP6R2,ST18,FAM131B,BOC,KATNAL2,TOX,ZFYVE16,LONRF1,DAPK1,AIF1L,SPATA2,ZEB2,ELMO1,CNIH3,TIAM2,RUSC2,BLOC1S6,DDX46,RHOBTB1,PLPPR4,SPOCK3,SV2A,GRIN3A,HS3ST2,DMTF1,DRD1,TOM1,DYRK1A,ABCC5,DNM1L,ATL1,HEYL,SEMA3D,TMTC1,FRY,RBM12,USPL1,ENO2,RCAN2,LRRC17,STX2,ERBB2,RCSD1,FAM198B,CEP78,FKTN,FER,AMOTL2,PRKAG2,UBE2E3,IP6K2,SYNCRIP,NELFCD,CAMKK2,CELF1,CGREF1,NSG1,MSANTD4,HHIPL1,FYB1,STAG2,GABRB1,GABRG2,CAB39,BRPF3,ARPP21,ZNF274,NEK6,C15orf41,ATP8A2,GART,LRRC37A6P,NFU1,PPARGC1A,ZNF276,TCERG1,COPS8,GNG4,FERMT2,WDFY3-AS2,ADGRA3,PRUNE2,GPM6A,GPM6B,PCLO,PLCD4,RFFL,GRIK2,GRM1,GRM7,GRM8,KIF3A,RNF165,COQ10A,BVES,MFSD2A,ZHX1,GABARAPL2,HMGCR,HNRNPK,ZDHHC15,NEGR1,SHISA6,SMAP1,ICA1,IRF8,GAREM2,RBPJ,TJAP1,LIX1,IL11RA,INPP5B,NME9,KCNB1,KCNH2,KCNJ10,KCNJ16,KCNK3,KCNMA1,KIT,IPO5,CYP27C1,STMN1,LMO2,VWA5A,GPR155,MAP2,MAP6,AQP11,SYT9,CHIC1,LRP1B,MEIS1,MEIS2,MID1,PPM1L,COL28A1,MSR1,N6AMT1,LYRM9,MYO7A,ZC3H12B,NEFH,NELL1,NFE2L2,NFYA,NINJ2,NRCAM,SMIM11A,NTRK2,NUCB2,TBC1D25,ODF2,OXTR,PBX1,PCSK1,PCSK5,PDCD2,PRTG,PDE1A,PDE1C,PDGFRA,ENPP2,SLC10A4,PFKFB2,OLA1,XRN1,PKM,PURG,PRIMPOL,CDIP1,LRP12,EXOSC10,PRRX1,MAGEL2,EPB41L4B,PPP1R1A,PKIA,PRKCB,RAB39A,EPDR1,SLC26A11,PRPH,GDPD1,MASP1,SLC22A23,SIDT1,SNRK,PSMD13,CNTLN,ANKHD1,UHRF1BP1,TMEM260,ZSCAN32,PTPN13,OCIAD1,PTPRE,PTPRO,TMEM145,NKAIN1,TTC13,PPP2R3C,TMEM255A,RAD52,RALGDS,SH3TC2,FAT4,SUSD4,ARID4A,KHDRBS2,TRIM68,RET,REV3L,RGS12,RIT2,MRPS18A,RNASEL,ZNF532,SETD5,MRAP2,GLDN,ADAL,LRRK2,ZNF568,DGLUCY,SALL1,SEMA6D,SCN8A,PRCD,SCP2,MRAS,NLGN4Y,KIF21A,ITSN1,SH3GL2,PPM1E,NTNG1,FBXO11,R3HDM2,ST3GAL3,ZNF365,SLC8A1,SIRT2,CCDC88A,SLC9A5,SLC20A2,SPHKAP,TET1,GKAP1,DMRTC1,KIF13A,UNC80,SON,SOX11,NMNAT2,MYCBP2,KDM4C,ZC3H13,KIF1B,ZBTB43,NPAS3,NFASC,SMOC1,SSTR1,NKAIN2,CEP68,DIP2A,ARHGEF9,C3orf70,ASTN2,KAZN,CAMTA1,CAMSAP2,UNC5D,TMEM136,ANO4,VWA3A,WSCD1,VWC2,SATB2,TCF7L2,CLASP1,SYNE1,DOCK9,RALYL,ARHGEF12,AHCYL2,RNF216P1,ZFPM2,CRB1,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,MTMR14,ACTR6,TLL2,HEY2,TMOD1,TNFRSF1B,R3HDM1,TPM3,C9orf85,ZNF384,RGMB,FNDC5,KCNE5,TSN,TSC1,CLHC1,TMEFF2,CADM1,RPRM,GORASP1,UGT8,ZNF709,TBC1D15,GUSBP1,XPO1,LGI4,ZNF28,SPHK2,LAMP5,ZFAND5,WNK1,PMEPA1,SLC38A1,PRDM10,RNF103,PPP1R3F,KCNAB1,C12orf4,UBE3B,FBXO36,NUP214,FXR1,SLC4A10,LAS1L" MicroRNA hsa-let-7g:mirSVR_lowEffct hsa-let-7g:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.96E-158 1.66E-154 1.11E-156 1.02E-155 429 1897 "SYS1,GALNT16,GALNT13,SLC12A5,SORCS1,ERMN,PLEKHH1,UNC5A,ADRA1B,OLMALINC,AP2A2,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,CDC42BPA,ANK1,ANK2,ANK3,LCORL,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM15,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,GPR37L1,ASIC3,MS4A7,RAB33A,TPP1,CLTA,ABCG2,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,ANKRD44,GDA,TRIM69,CS,RGS6,SEC24C,LRIG1,CSNK1E,SUSD5,PLXNA4,PPP1R16B,ERC2,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,SPATA2,DCT,ZBTB24,MED24,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,GRIN3A,DOCK2,DMTF1,SLC12A6,DPH1,FAM57B,PDCD6IP,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,ABCC9,SNX29,EDNRB,ANKRD46,CNNM1,RBM12,YAF2,PHF20L1,EBI3,EGR3,RASA4,GOLGA7,CERCAM,ELAVL4,STARD3NL,USPL1,EPB41L2,EPHB1,RABEPK,SRRM1,NCALD,CDHR1,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,TUBB4A,CORO2B,DLC1,RACK1,TOMM40L,GTF2IRD2,HPCAL4,CAP2,IP6K2,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,ATP8A2,KIAA1841,GHR,PPARGC1A,LYVE1,TOX3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,PTPN5,TMEM25,FICD,AP4S1,RABL2A,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,OPALIN,SMAP1,FAM95B1,MYLK2,C2orf72,LRRC25,IL11RA,INPP5B,ZNF385B,SLC35G1,CDH20,KCNC1,KCND1,KIF5C,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,MYCN,PABPC1L2A,NDUFA5,SFR1,NEFM,ALDH1L2,NME4,NOVA2,NPR2,SLC11A2,NTRK2,NTRK3,ZNF713,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB2,PFKFB3,CDK14,GDAP1L1,ZNF655,PLCB2,PLP1,HMGCLL1,C11orf49,TRHDE,SCHIP1,RANBP3L,PRKACB,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,UHRF1BP1,TMEM260,ZIK1,PTPRD,PTPRG,FAM120C,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,GAL3ST4,SLC6A15,KCTD17,RIT2,DCUN1D2,KLHDC8A,GSTCD,ROBO2,CCDC102B,EPHA10,RPL15,UEVLD,SPIN3,KIAA0895L,ACER3,PTGR2,MEG3,RTKN,TRAPPC13,ATXN2,HOGA1,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,STUM,FOXRED1,HSPA4L,ITSN1,PPM1E,CPEB3,CTXN2,WDR37,SLA,SLC1A7,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,KDM4D,SLC8A2,ATF7IP,SLCO1A2,CPEB4,MAST1,MYH15,IFT122,INAVA,RBM34,USP33,FAM219A,DOP1A,TNIK,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,SPTB,TSPYL2,RBM26,NPAS3,DDN,TAB2,POGZ,SSTR2,SYT11,MLC1,FNDC9,PLCB1,SLC37A2,TAC1,PDLIM2,FBXW11,VWA3A,RPGRIP1L,TCF12,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,AP4E1,FBXL16,ARL10,TK2,DAAM2,KCTD2,TNFRSF1B,NPL,C9orf85,WBP2,CHST5,RGMB,SMUG1,TRIO,TRO,STXBP4,TRPC3,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,ZNF709,VSNL1,WIPF1,ETNPPL,PCDH20,ZNF708,ZNF28,ZBTB16,MEIS3,WNK1,CSDE1,LINC02210,SIGLEC10,NAV3,FIP1L1,TRIM16L,UBE3B,KAT6A,FBXO36,CASC15,NUP214,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-548m:mirSVR_highEffct hsa-miR-548m:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.52E-158 2.54E-154 1.68E-156 1.55E-155 416 1788 "KCNH8,CLK4,KDM5D,CSMD3,KLHL32,DSCAML1,SLITRK1,BRAP,CDC7,ERMN,ADORA2A,PWWP2A,FAHD2CP,KIDINS220,BEND6,MTUS1,HECW2,OSBPL1A,KIAA1324,WDR35,CC2D2A,SRPX,FAM135A,KCNT1,DPP10,FGD2,CCDC146,MAP4K3,MYH7B,PPFIA1,APAF1,EPB41L5,TNRC6C,API5,SHTN1,PPP4R4,CDK13,NUMB,TMEM108,ATP1A2,ATP2B1,NOL4,DPY19L3,ADGRB3,PROM1,SYNJ1,C5,NGB,CAMK2G,VSTM2A,MAP7,INA,CD38,CD81,LRBA,SEPT7,CDH2,LGI1,MAGI1,TIGD7,SRSF11,B4GALT6,EPS15L1,PLAA,PPT2,CLCN3,C4orf33,QKI,MAP4K4,AKAP6,SLC4A7,ABI3BP,RTTN,CNRIP1,MFSD4A,SLC35F1,HAPLN1,NCOR1,ABCG1,ERC2,RIMS2,KIAA0408,BOC,DOCK4,HDAC9,DCAF8,FRMPD4,TBC1D5,LIN54,MATR3,KIAA0586,TMEM170A,PABPC5,ARMCX4,DNAJC6,ZEB2,CEP170,GSDME,DDX46,SMG7,CHRDL1,EXOG,DMD,USP3,CDON,CPEB2,PDCD6IP,DSCAM,GNE,ABCC9,GOLT1B,EBF1,EDNRA,EDNRB,FCF1,RASGRP1,KLHL5,FRY,FSD1L,RBM12,PHF20L1,EBI3,GOLGA7,KCTD3,IRAK4,TENM1,PLEKHA1,ELAVL4,STARD3NL,EPB41L2,KCNMB2,CEP85L,ETV1,TLR7,DLC1,CEP78,FKTN,GORAB,SLC9B2,FGF13,SUCO,UBE2E3,HPCAL4,CAP2,COQ5,PDLIM5,FAM49B,KHDRBS3,STAU2,PNMA2,AP4B1,ZNF512,OGA,CHL1,GABRB1,ILDR2,ZMYND11,ZNF234,DISC1,ATP8A2,WASF3,NEU3,ARFIP1,FREM1,TCERG1,COPS8,RNPS1,PCDH11X,ZNF638,CBX1,KDM2B,PRUNE2,GPM6A,GPM6B,GPR37,PCLO,DIDO1,GRM3,CIT,BTN2A1,RNF165,ADAMTS6,IRAK3,HAS2,NXPH2,DDX19B,MIER3,HMGB1,HMGCR,HNF4G,TCEAL6,SHISA6,ZNF546,C5orf24,RBPJ,PLD5,INSM1,TUBB2B,ZNF385B,NME9,ITGAV,JAK1,SLC35G1,METTL21A,CDH20,KIF2A,KIF5C,IPO5,STXBP5,KTN1,LAMP2,LIMS1,PAXBP1,MAP2,MARK1,LYPLAL1,MATN3,MDM4,MEIS2,SRSF12,MEST,KCTD6,MIA2,KITLG,POC1B,AFDN,MMP16,MOG,ZNF680,BLOC1S2,MSR1,ZNF92,MXI1,MYO9A,PABPC1L2A,BEX5,NAP1L1,FXYD6,NEUROD1,NOVA1,LRIT2,PCBP3,SLC11A2,NUCB1,OLR1,PAK3,PCDH9,PRTG,PDE4A,PDGFRA,PDPK1,ANLN,PLCL1,HMGCLL1,PURG,SPATA6,TNPO2,MINDY2,PPP2R5E,MAPK9,GRAMD1C,GON4L,SNRK,MDGA2,CNTLN,MTMR10,PTPRD,C1orf109,PTPRZ1,ACSM5,STRC,PLEKHB2,FAM66C,ZNF793,SH3TC2,FAT4,ZNF493,OXR1,MSANTD2,RFX4,NUDT11,RNASEL,RPRD1A,ZFHX4,CCDC82,ZNF532,RAVER2,CCDC25,RORB,PCMTD2,RPL15,ACER3,CLIP1,S100B,AMER2,ATXN7,SCN3A,TNFRSF19,GALNT10,SUPT20H,SCAF8,SH3GL2,ARX,CPEB3,MAGI3,FNDC3A,ANKRD6,BTBD3,CCDC88A,SLC12A2,SCMH1,ELMO2,BTBD7,SORCS3,CDK5RAP2,SMARCE1,RCOR3,LIMCH1,CMTR2,SNRPN,PALLD,UNC80,RBM34,USP33,SON,TNIK,BDP1,SPP1,BEX1,RBM26,NPAS3,NFASC,C11orf87,TAB2,ATP10B,NKAIN2,MPRIP,SEPT8,RGL1,PRRC2C,SYNE2,PLCB1,ANKRD28,C12orf76,CAMSAP2,ADGRL3,AGTPBP1,ANO4,TBX15,EHBP1,CUX2,ZEB1,WASHC4,PCDHB9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEK,DICER1,CRB1,HHIP,SLC44A1,TIAM1,HEY1,TJP1,ACTR6,ZFP91,BEX4,C5orf64,KAT6B,TPM3,SMUG1,TRPC3,DCBLD1,TSC1,SGK3,CADM1,RPRM,PITPNB,PLEKHH2,USP1,VLDLR,TBC1D15,P2RY12,GUSBP1,ZBTB14,ZIC1,ZNF708,ZNF17,KCNT2,REEP1,ANKS1B,SMARCAD1,WNK1,PCDH15,KCNAB1,PDSS2,EPM2A,DOCK8,MARCH8,UBE3B,PAK5,KAT6A,SMIM8,CASC15,ZNF248,RNF170,KLHDC1,FRMD6,NETO2,JPH3" MicroRNA hsa-miR-198:mirSVR_lowEffct hsa-miR-198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.26E-158 2.95E-154 1.94E-156 1.79E-155 412 1755 "EMILIN3,NBAT1,SYS1,CSMD3,NDRG3,GALNT16,AP2A2,KLHL13,PCDH19,TBC1D14,DISP3,AK2,LRRC7,SYT13,TRMT9B,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,APBA2,APBB2,EPB41L5,API5,PPFIA3,USP37,CPNE5,LGR5,SFMBT2,SEMA4G,LINC00173,ASPH,ZBTB10,NCOA1,ASTN1,TMEM108,ATM,ATP1A1,ATP2B2,RNF182,RIPK1,LINC00847,KSR1,LINC00906,C1QC,GYG2,MYRF,BTRC,CA12,CACNA1E,THSD7A,CAMK2G,TRIM41,CH25H,BRSK2,RUNX1T1,MTMR7,CDH8,LOC730101,NUMBL,CFL2,GPR37L1,SRSF11,CHN2,CASC2,EPS15L1,CPNE6,COG1,STOML1,CLTA,SULT4A1,SRP14-AS1,TMEM155,CNR1,COL4A5,COL9A2,SLC4A7,ABI3BP,TBPL1,COX4I1,BAG4,ZFP28,AKAP12,NCOR2,GDA,TRIM69,ABCG1,CS,CSF1,SEC24C,NCAN,VAC14-AS1,ERC2,CMTM5,ARHGEF4,CTNND1,BOC,DOCK4,HDAC9,ARHGAP32,GAPVD1,TCAF1,PHF19,ZFYVE16,EARS2,TOMM20,ZEB2,ZBTB24,PLEKHM1,HEPH,ELMO1,MFAP3L,COPS7A,KIAA0319,CEP170,POM121,SACS,SRGAP3,CHRDL1,DLG2,DLG3,EXOG,GRIN3A,DMD,DPP6,PDCD6IP,ARRDC4,DUSP9,DNAJB6,DYRK1A,AASDH,HIPK3,HEYL,FAM13A,PHF20L1,SUGP2,ABI2,SORBS3,CERCAM,EMX2,EPB41L2,EPHB1,SPEG,ETV1,DUSP27,SIRPB1,KATNAL1,MRVI1,RPS6KC1,PTK2B,CEP78,CHST15,TOMM40L,FDFT1,KAT8,ZNF589,GTF2IRD2,KIAA1109,AMOTL2,HPCAL4,SLC37A3,HVCN1,CAMKK2,ATP6V1H,ADGRA1,ZMAT1,GABRA5,ILDR2,GAD1,BRPF3,ARPP21,IQGAP2,DISC1,NEU3,TUBGCP4,ADAM28,GFRA2,GGT5,TCERG1,COPS8,GLYR1,PCDH11X,STARD3,OS9,GNG4,CNDP1,LILRA1,CCDC184,GRIA4,SPACA9,ADAMTS13,GRM7,BTN2A1,RNF165,COQ10A,MFSD2A,RABL2A,LINGO1,TOX2,MAN1B1,ATXN2L,TNFAIP8L3,GABARAPL2,SYNPO,HNRNPK,TLX1,SHISA6,CELF5,HTR2A,DOCK7,METTL21A,KCND1,KCNH2,KIF2A,MAN2A2,MATN2,CHIC1,LDLRAD3,MEIS1,AFDN,MOBP,SAMD5,COMMD5,ADAM22,CTNNA3,MTTP,LYRM9,MYO7A,NCAM1,ZC3H12B,NF1,NFYA,NOVA1,DNHD1,SMIM11A,NUCB2,SETD4,OGG1,OLR1,OMG,OXTR,PBX1,PDE3B,PFKFB3,NLGN3,PIK3C2A,PDZRN4,POU6F1,PPP2R5E,PPP3CA,PPP3CB,KANSL1,PRKAB2,PKIA,PRKCG,PRKCZ,GDPD1,PSD,SLC22A23,WDR25,PTCH1,BDNF-AS,MTMR10,ELOVL2,DKFZp779M0652,PTPRB,PTPRG,PEX2,TTC13,STRC,MARCH1,TMEM255A,RAD52,FAM66C,RALGDS,ATG16L1,RAP1GAP,SUSD4,NWD1,ZYG11B,PRRT2,RFX2,RFX4,UBR7,RGS3,TTLL7,SEC61A2,RNF220,TMLHE,RAVER2,ROBO1,KIRREL1,PCMTD2,SNX22,NEK11,FBXW7,ZC3H14,SGSM1,RIMKLA,LGR4,MEG3,ATAT1,RTN1,AMER2,LRFN5,PEAR1,SOX6,TRIM46,ZNF821,GALNT10,STUM,PPM1E,ASAP3,MYO18A,HKDC1,ST6GAL1,NLGN1,CTXN2,PAAF1,SLA,EPN2,PKNOX2,SLC8A1,RTP5,ELMO2,BTBD7,ATF7IP,NAXD,SMARCD3,INTS9,SCN3B,DOP1A,SON,WDTC1,SOX2,SOX5,CLUAP1,SPP1,UNC5B,RBM26,SRPK2,TAB2,POGZ,COLGALT2,SS18,STAC2,PHLDB1,ARHGEF9,NUDT10,ARC,SLC37A2,KAZN,ROBO3,CAMSAP2,TBCEL,KLHL4,TBX15,EHBP1,WSCD1,TCF7L2,DOCK9,RALYL,PMS2CL,DICER1-AS1,AP4E1,GALNT17,ARL10,ENHO,TLL2,TMPO,DAAM2,R3HDM1,PIK3R5,SEZ6L,TPD52L2,TPM1,TPM2,SMUG1,STXBP4,PPIL6,FNDC5,ZKSCAN5,TMEFF2,AMOT,VAV2,RBFOX3,WIPF1,NSD2,WNT7A,LGI4,SLC47A2,SF1,ELFN1,ZNF177,POLR3H,EML6,CADM2,LMAN2L,NAV3,FIP1L1,SLC17A6,PDSS2,FZD3,UBE3B,KAT6A,SMIM8,PHTF2,CASC15,ACTR3B,RSPRY1,ZDHHC20,PIANP,SOCS4,FAM198A" MicroRNA hsa-miR-20a*:mirSVR_highEffct hsa-miR-20a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.82E-158 3.27E-154 2.14E-156 1.97E-155 383 1518 "ACADM,ACLY,FMNL2,ADD3,BEND6,DPY19L2P4,ZNF608,INTS2,HECW2,OSBPL1A,NR0B1,TXNDC16,LRRC7,AMPD3,OGT,CDC42BPA,LRCH2,ANK3,PHF12,CNTNAP1,APC,GPAM,ALS2,PHYHD1,CACHD1,AQP6,MIER1,SFMBT2,PPP4R4,ZFYVE28,LINC00173,PDE8B,ATM,EIF4G3,ATP2B1,SLC2A11,B3GALT2,MYOM1,DOCK11,ADAM23,BACH1,ADGRB3,MPDZ,DCAF5,NRP2,CA8,KALRN,PRC1,KRIT1,METTL6,MTMR7,AIFM1,CBFA2T2,CDC27,ZBED1,CDC42,LRRFIP1,CFL2,CHN2,CASC2,SYNPR,NDST3,NRXN3,NRXN2,FAM189A2,DNAJB5,NIPBL,IQCK,AKAP6,SLC4A8,RCHY1,MFSD4A,CHD1L,CLOCK,RBM39,ANKRD44,TENM4,CSF1R,RGS6,CSF2RA,CSNK1G3,ATRNL1,SOCS5,VAC14-AS1,PHF14,ST18,ZSCAN23,DCAF4,USP6NL,CYBB,HDAC9,RIPOR2,TOX,KIAA0513,MATR3,DGKB,DAPK1,TOMM20,GIT2,SPATA2,DNAJC6,C8orf34,MYEF2,CNIH3,ALKBH8,SV2A,CHRDL1,DLG2,EXOG,NR1D2,CPEB2,PDCD6IP,ECM2,MAMLD1,DYRK1A,ABCC9,EBF1,HEYL,OPTN,KMT5B,ING4,DCTN4,EPHA5,GPHN,NCALD,CDKL3,EXTL2,FAM198B,WAC,RPS6KC1,ACSL4,FCGR1A,CHST15,SLC9B2,FER,FGF11,SUCO,SEC23B,IQCG,ANKFY1,NOP56,SMC2,APOPT1,PDLIM5,FAM49B,NPTN,ATP6V1H,CELF1,DACH2,TMEM151A,AP4B1,GABRG1,GALC,SALL3,ZNF234,SIGLEC8,SEPT9,DNER,MSTN,ADAM28,DHRS4,GK,GLRB,PCDH11X,ADGRA3,GPM6A,GRID1,GRIK2,GSN,RASSF8,HAS2,FRMD3,BACH2,MIER3,HMGB1,ZNF491,TLX1,SHISA6,HTR5A,SOWAHA,RBPJ,DOCK7,KCNA2,KCND2,KLHL23,KCNK2,KIF5A,KLRC3,LAMP2,HECTD2,FGFBP3,NCOA7,MAT2A,MATN2,MBNL1,SYT9,TM6SF1,AFDN,MMP16,WDR49,CD200,ZNF680,MRPL42,JAKMIP3,NRBP2,ZNF92,MYO9A,NAP1L2,NDUFA5,NELL2,NEUROD1,NF1,CNOT4,NRCAM,NUCB2,SETD4,CNTN3,DPY19L2P2,GPR85,NALCN,PIK3C2A,ZNF655,FTO,STRN3,LRP12,SPATA6,SH3KBP1,POU3F2,PPM1B,PPP3CA,NKAIN4,PKIA,MAPK10,GRAMD1C,MASP1,SAMD9,APTX,PIGG,CNTLN,PTCH1,PTHLH,TMEM260,PTPN13,PTPRE,ACSM5,TTC13,ZNF615,USP47,FAM66C,RAP1GDS1,ZNF493,RASGRF2,RADX,VEPH1,RET,REV3L,GTDC1,FIGN,RFX3,RGS7,RGS12,RIC8B,RPRD1A,CCDC82,TMLHE,C12orf49,CARF,ROBO1,ATP8B4,ACER3,CNTNAP3,ABCA11P,ATAT1,ZNF568,RYR3,NCBP3,SEMA6D,SATB1,ATXN7,SCN8A,SFPQ,NLGN4Y,ZFP30,CPEB3,MYO18A,SHC4,FBXO11,ZNF365,BTBD3,WDR47,RUFY2,SLC6A1,SLC15A2,SLCO1A2,SPHKAP,TET1,CPEB4,SORCS3,CDK5RAP2,SMARCE1,ANKRD36,KIF13A,SNRPN,KDM4C,RBM26,NPAS3,LHPP,COLGALT2,ZNF302,SSTR2,SEPT8,CEP68,RGL1,AJAP1,VPS13A,PJA1,MCF2L,TAF9,CAMSAP2,KIAA1107,WWC1,VWA3A,ATMIN,VWC2,TCF4,RPGRIP1L,SYNE1,RALYL,SLC35G2,SIK3,DNAH7,SIRT1,C18orf54,AP4E1,CDH22,ASXL3,DDHD1,ERCC6L2,R3HDM1,KAT6B,TPD52L2,SYNPO2,RUNDC3B,CA14,RFTN2,TTPA,UBE3A,UGT8,VSNL1,NSD2,RICTOR,SF1,ZBTB14,ZIC3,ZNF708,MICU3,ZNF45,GPR158-AS1,ZBTB38,ZNF154,FTSJ1,SMARCAD1,DHX33,CADM2,PRTFDC1,TMEM178A,HPS4,PCDH15,NAV3,WNK2,PDSS2,GOPC,HNRNPA3,TIGD6,RNF170,MSRB3,SLC39A12,SSPN,KLHDC1,FXR1,IFT88,SLC4A10,GAN" MicroRNA hsa-miR-890:mirSVR_lowEffct hsa-miR-890:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.92E-158 3.33E-154 2.16E-156 1.99E-155 396 1623 "ADAR,DSCAML1,ADCY6,GALNT13,AXIN2,PLEKHH1,USP31,ESYT2,BEND6,MTA3,SLC24A4,AP2A2,MTUS1,PCDH19,CC2D2A,SEMA6A,FAM135A,AMPD2,OGT,DPP10,ANK1,PI16,PPFIA1,APC,ALS2,LGR5,AQP4,TMEFF1,ARHGAP5,ARNTL,CDK13,CCDC74A,CHRD,NUMB,TMEM108,EIF4G3,ATP1B3,SEC11C,BCL2L2,DST,FUBP1,CDK5R2,CA4,CACNA1E,HAP1,PRC1,P2RX6,SCARB1,TMEM257,CDH10,MAGI1,COPB2,FOXN3,CHN2,TPP1,ABCG2,NIPBL,CNR1,AKAP6,WHRN,CABP1,SUMF2,LETMD1,SLC4A8,ABI3BP,RCHY1,COX4I1,BAG4,ZNF521,ZNF385A,SLC35F1,AKAP12,CRY2,ANKRD44,GDA,OSBPL3,PLCH2,VCAN,NCAN,SOCS5,PDE4DIP,PHF14,GREB1,CTNND2,RIMS2,BOC,DOCK4,HDAC9,ARHGAP32,TOX,EARS2,DAPK1,SCRN1,B3GAT3,HP1BP3,COPS7A,MAGI2,BLOC1S6,PLPPR4,SPOCK3,RABGAP1L,FAM107B,CHRDL1,DLG2,DMD,DNM2,RCAN1,GNE,MAMLD1,EDN1,ANKRD46,SGK2,FCF1,EFNB3,PHF20L1,MRO,KCTD3,TMEM35A,EML1,EMX2,COQ7,NCALD,ZNF549,DNAJC27,KATNAL1,ADGRV1,NRN1,FAM198B,CACNG3,TAOK3,EFEMP1,FCGR1A,CEP78,FCGR3A,ZSCAN30,FDFT1,FECH,SEC24B,CAMSAP1,SUCO,MEX3B,HPCAL4,SYNCRIP,FOXM1,FOXO3,FLYWCH1,C2orf88,TACC2,SPECC1,STAMBP,KHDRBS3,NSG2,ABLIM2,ZMAT1,STAG2,MEGF11,GALNT15,GABRG1,B4GALNT1,ARPP21,ZNF274,NEK6,DISC1,NEU3,TUBGCP4,GPR162,ADAM28,MMADHC,GK,MSL3,DCLK2,LILRB4,GPR12,CCDC184,B4GALNT4,GPR19,STON1,GRID1,PLPP7,GRM7,FAM19A2,PADI2,ARHGAP19,SHISA6,ICA1,MSL1,IGF1,SCIN,INPP5B,ITGAM,KCNJ3,KCNK3,STXBP5,L1CAM,TTYH2,LIFR,LMO2,MAPT,LDLRAD3,LRP1B,MEST,KCTD6,PPM1L,MPP2,MRPL42,JAKMIP3,LYRM9,ZNF862,ZC3H12B,NDP,NEFH,NEK1,NFYA,LRIT2,NPR2,NTRK2,NTRK3,OCRL,P2RY1,PAH,TREM2,SNTG1,PAX6,PDGFRA,PENK,NALCN,PIK3R1,CCSER2,PLP1,HMGCLL1,STRN3,LRP12,RETREG2,SLC36A4,FAT3,NXPH1,SH3KBP1,PPARA,PTPA,PPP3CA,CEP41,RAB39A,PRKCZ,MAPK9,MAPK10,PRPSAP2,MASP1,SAMD9,WBP1L,SIDT1,MDGA2,PTPRD,PTPRO,PTPRZ1,TUG1,MARCH1,PID1,CEP97,RAD51D,RAP1GDS1,OXR1,RASGRF1,DBX2,KHDRBS2,MSANTD2,RDX,SLC6A15,ZYG11B,RFX4,UBR7,RGS3,PRIMA1,SEC61A2,SLC25A36,RNASEL,CARF,PCMTD2,EPHA10,ZNF671,GLDN,SGSM1,CNTNAP3,WLS,KCNIP2,KCNIP1,ZNF331,SCN4B,TNFRSF19,SLC30A10,ITSN1,KIF16B,CPEB3,MAGI3,FNDC3A,FHOD3,CCDC92,ST3GAL3,SLA,WDR47,FAM214B,SLC6A1,LRRC55,NAPB,BTBD7,SLC20A2,SORCS3,RCOR3,SNCA,SON,SOX5,BDP1,GLT8D1,EMC1,CAND2,UHRF1BP1L,ERC1,C11orf87,ATP10B,ITPRID2,ZNF302,SST,EPB41L3,LARP4,INKA2,DIP2A,KANK1,SULF2,NECAB1,SYT11,SYNE2,RHBDL3,ANKRD28,TACR1,DNMBP,ALG1,TBCEL,FBXW11,TBX15,WSCD1,TCF4,KIAA0930,CUX2,USP22,SYNE1,TNS2,RNF175,TEX15,FAM200B,CRB1,AP4E1,HHIP,SLC44A1,HEY1,ACTR6,TMPO,R3HDM1,C9orf85,PRMT8,ELP5,TRIO,RFTN2,AMOT,VGF,TBC1D15,RBFOX3,NSD2,WRN,RICTOR,GUSBP1,ETNPPL,ZNF24,MICU3,FMN2,MKRN3,CELF4,POLR3H,ZNF189,FTSJ1,LAMP5,ZFAND5,EVI5,PRDM8,LMAN2L,HPS4,SEMA3B,PCDH15,GAL3ST3,FIP1L1,AMN1,SMIM8,NUP214,VANGL2,PIANP,SOCS4,SLC4A10,JPH3" MicroRNA hsa-miR-101*:mirSVR_lowEffct hsa-miR-101*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.30E-158 3.54E-154 2.27E-156 2.09E-155 407 1714 "ACADM,SYS1,ARID1A,CSMD3,ADD3,PWWP2A,KIAA1211,NLGN4X,SLC44A5,INTS2,HECW2,CASKIN1,OSBPL1A,OSBPL6,AK2,SPARCL1,PCDH10,EP400,C6orf89,CCDC146,SHTN1,PPP4R4,ATM,ATP2B1,ATP2B3,ZNF583,RNF182,B3GALT2,BACH1,SNAI3-AS1,MPDZ,SYNJ1,FUBP1,NAE1,SGCE,NIPA1,WASF1,CACNG1,RHBDL1,RUNX1T1,CLDN10,USP2,MTMR7,CD38,CDK11B,LRBA,REPS2,CDC27,DCLK1,LRRFIP1,SRSF11,B4GALT6,CNOT8,NRXN3,ZFYVE9,TJP2,FAM19A5,C4orf33,MAP4K4,ARHGEF6,CNTN1,CABP1,RTTN,CHD1L,SLC35F1,FAM171B,SEC31B,CLOCK,ENTPD4,CRHBP,HAPLN1,GDA,SNCAIP,TENM4,CSF2RA,OSBPL3,VCAN,PHACTR3,DZIP3,CTH,NRSN1,EDRF1,CCDC144A,NOS1AP,HDAC9,FGFR1OP2,TOX,PITPNC1,DNAJC6,ZNF804A,C8orf34,ZBTB24,TIAM2,MFAP3L,ARRDC4,DNAJB6,FARSB,ABCC9,E2F5,EDIL3,CNNM1,KLHL5,FAM13A,MRO,ABI2,RASA4,GOLGA7,PLEKHA1,RGS17,EML1,USPL1,LRRC17,KCNMB2,GPHN,IGSF6,RCSD1,RRAGB,F5,EFEMP1,FCGR1B,ST3GAL6,FKTN,KIAA1109,POLK,FOXG1,CAP2,PCYOX1,SYNCRIP,EFCAB2,ZCCHC17,STAMBP,DACH2,ST6GALNAC3,STAU2,MSANTD4,ZNF512,OGA,PHYHIPL,ZMAT1,GABRA1,GABRA2,GABRA3,GABRG1,TRAF3IP2,ZMYND11,RAPGEF6,ZNF274,DISC1,WASF3,KIAA1841,MYOZ2,GATM,FAXC,MSTN,SESN1,ADAM28,GHR,PPARGC1A,MALT1,RAB30,GLRB,PCDH11X,LUZP2,GNAL,GPD2,STON1,GPR34,PCLO,CNTRL,DIDO1,GRIA4,RFFL,GRIK1,GRIK2,NR3C1,PRDM5,GRM7,BVES,MFSD2A,HAS2,PADI2,ZHX1,ATXN2L,LINC01102,HNMT,CELF5,HTR2A,MSL1,IGFBP1,LRRCC1,TJAP1,PLD5,IL12A,INSM1,KCNA6,KCNH2,KCNK2,LIMS1,PAXBP1,ARHGAP12,MAOB,LYPLAL1,MARK3,SRSF12,MIA2,MID1,COL28A1,CCDC80,CTNNA3,LYRM9,MYT1,NDP,NDUFA5,NEUROD1,SLCO1C1,NFYA,NOVA1,OPHN1,CNTN3,ETFRF1,PCDH8,PCDH9,PRTG,PDGFRA,GPR85,PFKFB2,PIK3R1,ZNF655,PCDH18,HMGCLL1,MTRF1L,PURG,PRIMPOL,PDZRN4,PMP22,PPM1B,LRRN3,RANBP3L,MAPK4,HYDIN,PRPSAP2,CNTLN,BDNF-AS,PTN,PTPN13,PTPRD,PTPRE,PTPRZ1,TUG1,MARCH1,RAP1GDS1,OXR1,DBX2,FEZF2,RADX,KHDRBS2,ZYG11B,ZMAT4,RGS10,TTLL7,SEC61A2,NUDT11,ZNF532,RPE,TMEM100,GLDN,LGR4,WLS,RTN1,RXRA,ZNF331,CSRNP3,LINC00461,SCP2,FNIP1,SLC30A10,IL17RB,SOX6,KIF27,RASA3,ITSN1,CPEB3,DOCK10,NTNG1,MAGI3,CHD9,FBXO11,FHOD3,NLGN1,ANKRD6,NUBPL,SLC1A3,FAM81A,SLC12A2,SLC20A2,CPEB4,RCOR3,ANKRD36,LIMCH1,SNAP25,MBD5,PDZRN3,MYO16,SON,PDZD2,SOX2,TNIK,KDM3A,SP4,NMNAT2,CLUAP1,MYCBP2,SPP1,KDM4C,ERC1,PEG10,ARHGAP26,TSPYL2,RBM26,NPAS3,TAB2,PBLD,SMOC1,SST,SEPT8,ADHFE1,SULF2,AJAP1,GSE1,FGD4,PRRC2C,SLC37A2,POPDC3,ATP11A,ANKRD12,MTCL1,ADGRL3,AGTPBP1,KLHL4,SATB2,TCF7L2,TPCN2,RPGRIP1L,WDR7,PCDHB9,PCDHB4,PCDHB3,ARHGEF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,AHCYL2,ZFPM2,ITGB3BP,GZF1,DDHD1,TLL2,BHLHB9,ERCC6L2,FAM124A,R3HDM1,TPD52,TPM3,WBP2,RGMB,SYNPO2,PDSS1,STXBP4,TRPS1,TUBB1,SLAIN1,PITPNB,NSD2,WRN,RICTOR,PCDH20,ZIC3,KCNT2,ZBTB38,FSTL5,ZSCAN26,UPF3A,WNK1,EMSY,CADM2,PRTFDC1,HPS4,WIPF2,SLC17A6,EPM2A,FAM13C,AMN1,FZD3,CASC15,ZDHHC20,SSPN,IFT88,SLC4A10,ZNF30,CPNE4,SENP7" MicroRNA hsa-miR-519b-3p:mirSVR_lowEffct hsa-miR-519b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.30E-158 3.54E-154 2.27E-156 2.09E-155 407 1714 "SYS1,ACTN2,SLC25A25,CSMD3,GALNT16,CCDC85A,ADD1,SORCS1,USP31,RNF150,ADRA1B,BEND6,HECW2,KIAA1324,WDR35,OSBPL8,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,GPAM,DGKD,TNRC6C,MIER1,CDK10,ARHGAP5,PLA2G4C,MARCH3,NCOA1,NUMB,DDX3Y,INSYN2B,DPY19L3,ADGRB3,RGS11,BCL2L2,BCL7A,FUBP1,MTMR2,SGCE,NIPA1,OSGIN2,BTRC,CACNA1E,KALRN,NGB,CAMK2D,CAMK2G,SYT6,CBR1,CBFA2T2,C1orf52,REPS2,CDC27,LGI1,NOG,CASC2,MS4A7,SYNPR,B4GALT6,KMT2C,EPS15L1,CLCN4,CLTC,QKI,CNR1,IQCK,PCYT1B,SLC4A7,IFFO1,ZFP28,CNRIP1,MFSD4A,PNKD,CREB5,AKAP12,HAPLN1,TRIM69,FEZ2,ATRNL1,PDE4DIP,CNTNAP2,FAM169A,APPL1,ST18,DCAF4,RUBCN,NOS1AP,GAPVD1,FRMPD4,ZNF337,DGKB,DGKG,DNAL1,SPATA2,C8orf34,ZEB2,MFAP3L,HP1BP3,CEP170,ZC3H11A,GUCD1,RHOBTB1,SNAP91,SRGAP3,G3BP2,DLG2,HS3ST4,HS3ST2,CPEB2,DMTF1,SLC25A18,DRD1,ACOT8,ABI1,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,ELAVL2,BSCL2,PAN3,EMX2,EPB41L1,EPHA5,ANKRD13B,EPS8,ERBB4,MRPL37,TLR7,KATNAL1,WAC,ST3GAL6,MED12L,CAMSAP1,POLK,SEC23B,PCYOX1,ATP13A4,ANKFY1,SGIP1,NOP56,NELFCD,TACC2,NPTN,CELF1,GABRB1,GAD1,HBS1L,ZMYND11,ZNF274,GAP43,GART,DNER,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,DBF4,TNRC6A,MSL3,CBX1,INSM2,GPT2,ADGRA3,GPD2,GPM6A,DIPK1C,GPR34,NUDT21,PCLO,RAPGEF1,GRIA1,NR3C1,ZNF496,BTN2A1,MFSD2A,SOX21,GUCY1A1,WIF1,IRAK3,GPR45,PTGDR2,HNF4G,DHX35,SHISA6,CELF5,IGF1,IL11RA,INPP5B,SLC35G1,KCNA1,KCNA6,KCNC2,KIT,LAMP2,CAMK2N2,SFXN5,LMO2,C2orf80,ZNF667-AS1,MAP2,MAP6,MAPT,LDLRAD3,SCAMP5,AFF1,JAKMIP3,PTOV1,NRBP2,TAGLN3,MTR,LYRM9,MYH6,MYO5A,MYO9A,NAP1L1,NAP1L2,P2RY13,NBL1,NCF2,NDUFA5,SFR1,NFIA,NFIX,NHLH1,NPTX2,NUCB2,OPRL1,KCNK10,PAX6,PBX1,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,PFKP,CDK14,DUSP26,SSH1,XRN1,GPSM2,SLC25A23,LRP12,PRRX1,SDK2,ING3,MED1,MINDY2,CCDC144B,PRKCZ,MAPK3,MAPK4,DEF8,MDGA2,MTMR10,OCIAD1,PTPRD,PTPRE,FAM184A,RBBP8,RADX,BSDC1,REV3L,GTDC1,PRIMA1,RPRD1A,LGI2,ROBO2,ELP2,TMEM100,NEK11,FBXW7,ZC3H14,GLDN,RPS20,CLIP1,ZNF331,FAM182A,AMER2,SATB1,ATXN1,SCN2B,TNFRSF19,PEAR1,TRIM46,PUF60,MAGI3,FBXO11,NUBPL,CLSTN1,WDR37,BTBD3,SMTN,WDR47,SLC6A8,KDM4D,SLC8A1,SLC11A1,SHANK2,SLC12A2,NAPB,SLC15A2,TET1,CPEB4,ZNF667,SORCS3,TTC17,RIMS1,SNAP25,SNCA,MBD5,PDZD2,TNIK,KIF21B,FNBP1,SP4,UHRF1BP1L,KDM4C,IDI2-AS1,ZBTB43,TSPYL2,RBM26,NFASC,SRPK2,EPB41L3,SEPT8,DIP2A,AJAP1,NSFL1C,MLC1,SYN2,ATP11A,TACC1,MTCL1,EXOC7,UNC5D,TMEM136,ATMIN,TCF4,CUX2,ZEB1,AZIN2,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,CRB1,ITGB3BP,AP4E1,TIAM1,ZFP91,RIMBP2,RGMB,SMUG1,TRPS1,TUB,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,CLDND1,MICU3,KCNT2,LYPD6,ZBTB38,SYNC,EMSY,PRDM2,SLC38A1,EVI5,STOX2,PRDM8,PCDH15,NAV2,SLC17A7,C12orf4,GOPC,FAM13C,FZD3,ST7,UBE3B,PAK5,FBXO36,FAM219B,NLRP3,TTC7A,SLC39A12,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-let-7f:mirSVR_lowEffct hsa-let-7f:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.98E-158 3.92E-154 2.50E-156 2.30E-155 416 1790 "AS3MT,CSMD3,GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,ADORA3,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,ANK1,ANK3,LCORL,PHF12,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM15,MPDZ,MTMR2,NIPA1,BTRC,CA12,CACNB4,PTBP2,CAST,MAP7,NFS1,ZNF501,USP6,SLC16A4,CD86,LRBA,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,ASIC3,CHN2,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,TRIM69,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,DCAF4,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,DCT,ZBTB24,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,PDCD6IP,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,SNX29,EDNRB,ANKRD46,RBM12,YAF2,PHF20L1,EBI3,EGR3,RASA4,GOLGA7,CERCAM,ELAVL4,STARD3NL,EPB41L2,EPHB1,RABEPK,NCALD,CDHR1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,TOMM40L,GTF2IRD2,CAP2,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,PNMA2,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,ATP8A2,SULT1C4,GHR,PPARGC1A,LYVE1,RUNDC3A,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,RABL2A,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,HMGCR,OPALIN,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,KCNJ10,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,MYO9A,PABPC1L2A,NDUFA5,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,PCSK1,PCSK5,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PKD1,PLCB2,PLP1,HMGCLL1,C11orf49,TRHDE,SCHIP1,RANBP3L,PRKACB,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LAMA1,DEF8,WDR25,PIGG,PTAFR,TMEM260,PTPRD,PTPRG,FAM120C,NKAIN1,TUG1,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,TRIM68,KCTD17,RIT2,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,KIAA0895L,ACER3,PTGR2,MEG3,RTKN,TRAPPC13,ATXN2,SCN4B,ASIC4,SEC14L1,CASC3,STUM,FOXRED1,HSPA4L,SH3BP2,ITSN1,CPEB3,ST6GAL1,CTXN2,WDR37,SLC1A7,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,KDM4D,SLC8A2,ATF7IP,SLCO1A2,CPEB4,MAST1,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,TAB2,POGZ,ITPRID2,STOX1,SYT11,MLC1,FNDC9,PLCB1,SLC37A2,TAC1,FAM208A,PDLIM2,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,AP4E1,FBXL16,ARL10,TIAM1,TK2,ERCC6L2,KCTD2,TNFRSF1B,C5orf64,NPL,TPM3,CHST5,RGMB,SMUG1,TRIO,STXBP4,TRPC3,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,ZNF709,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF28,ZBTB16,EML6,MEIS3,WNK1,LRP8,CSDE1,FIP1L1,TRIM16L,ST7,UBE3B,KAT6A,CASC15,NUP214,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-381:mirSVR_highEffct hsa-miR-381:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.42E-158 4.17E-154 2.64E-156 2.43E-155 383 1519 "DPF1,ACADM,CSMD3,CCDC85A,ADORA3,ADRA1B,NLGN4X,GPR158,KCTD16,ABCD2,PCDH10,FAM135A,LRFN1,ANK3,PPFIA1,APAF1,DGKD,SHTN1,MIER1,ARNTL,ASPH,ZBTB10,NUMB,EIF4G3,STX16,ATP2A2,ATP2B1,RNF182,DOCK11,CARMIL3,BACH1,DST,NAE1,SGCE,RAB29,IL33,CACNB2,THSD7A,KALRN,SPAG9,ZNF501,LDB2,AIFM1,CDH2,CDH10,MAGI1,CFL2,B4GALT6,KMT2C,RAB33A,RAB28,NRXN1,NGEF,HECTD1,ARMC8,BTF3L4,ABI3BP,AHCTF1,ACBD5,ZNF521,MFSD4A,TRIM69,FEZ2,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,CST3,PLXNA4,PNPLA8,BOC,DOCK4,HDAC9,ARHGAP24,TOMM20,PABPC5,GIT2,ARMCX2,YTHDC1,C8orf34,BLOC1S6,ZC3H11A,G3BP2,RABGAP1L,FAM107B,CHRDL1,RAB39B,DNM2,DMTF1,DPP6,DRD1,DYRK1A,E2F5,EBF1,SNX29,ANKRD46,CNNM1,KLHL5,FSD1L,PHF20L1,MBNL2,KMT5B,KCTD3,EIF4G2,TENM1,EML1,PAN3,EIF1,VPS13B,EPB41,EPB41L1,EPB41L2,LRRC17,EPHA5,EPHB1,KCNMB2,EPS8,CEP85L,RRAGB,DLC1,TESK2,ZNF589,FGF1,POLR1B,BAIAP2,POLK,ATP5PD,FOXG1,FOXF2,PCYOX1,SYNCRIP,FOXO3,ATP13A4,NBEA,SORBS1,SMC2,UFM1,ATP6V1H,PRELID3A,STAU2,MSANTD4,PHYHIPL,STAG2,GABRA2,GABRB3,GAD1,ZMYND11,GALC,B4GALNT1,RAPGEF6,ARPP21,NEK6,NCKAP1,MTHFD2,C15orf41,KIAA1841,AHDC1,RUNDC3A,GLRB,TNRC6A,PCDH11X,MAP7D2,KCNMB4,ADGRA3,TDRKH,LILRA1,GPR34,CECR2,PCLO,GRIA1,GRIA2,RFFL,NR3C1,GRM3,GRM5,GRM8,KAT7,AP4S1,PSIP1,ADAMTS6,FAM222A,IRAK3,MIER3,HMGB1,USP51,TCEAL6,ZNF546,IGFBP1,ZIC5,RBPJ,ZNF678,RIPPLY2,ITGAV,JAK2,KCNA4,KCND2,KCNJ3,KIT,STXBP5,VWA5A,HECTD2,MAP4,MARK1,MATN2,MBNL1,LRP1B,MEIS2,SRSF12,MITF,ERICH3,ZNF680,MSR1,MYO9A,NEXMIF,NAP1L1,NAP1L2,NAP1L3,P2RY13,NCAM1,NEUROD1,NF1,CNOT4,HCN1,OPHN1,CNTN3,PBX1,PCDH8,PCSK2,PDE1C,ENPP2,PENK,ZNF655,FAM218A,A2ML1,CCSER2,XRN1,KCTD15,NLE1,PLCL1,HMGCLL1,PURG,PMP22,ING3,FA2H,POU3F2,KANSL1,RANBP3L,PRKACB,CEP41,MAPK4,GDPD1,SNRK,PTCH1,ANKHD1,TMEM260,OCIAD1,PEX2,TMEM231,RAP1GDS1,OXR1,MSANTD2,SLC6A15,REV3L,GTDC1,SLC25A36,RIC8B,PBRM1,RPRD1A,ZNF532,GSTCD,ROBO2,RPS20,SYNDIG1,ABCA11P,WLS,SALL1,SEMA6D,SATB1,SCN7A,FNIP1,TNFRSF19,CASC3,SFPQ,SCAF8,KIF21A,SH3GL3,PPM1E,ARX,CHD9,R3HDM2,CNKSR2,SYBU,PAAF1,WDR37,PPP4R3A,EPN2,RUFY2,SLC6A8,ATF7IP,GKAP1,INAVA,MBD5,KIF13A,UNC80,TRERF1,KIF21B,SP4,SPTB,KIF1B,IQSEC2,RBM26,DDN,LMO3,PBLD,CLSTN2,SAMSN1,SSTR2,EPB41L3,LRRC4,NXT2,SEPT8,GANAB,SYT11,VAMP1,ARHGEF9,POPDC3,ANO4,TBX15,EHBP1,ZEB1,SYNE1,PCDHB4,FRYL,HIF3A,TEX15,TEK,DICER1,ZFPM2,ZMAT3,TGFBR3,HHIP,NACC2,HEY1,ACTR6,ASXL3,BEX4,R3HDM1,KAT6B,TP53BP1,TP53BP2,TRIO,TRO,SSBP2,ZKSCAN5,SGK3,UBE3A,USP1,ZNF709,BEST1,TBC1D15,VSNL1,PCDH20,ZBTB14,MICU3,FMN2,LYPD6,ANKS1B,UPF3A,EMSY,LRP8,MDH1B,PCDH15,NAV3,SNX27,SLC17A6,DNAH10,FAM13C,AMN1,PHTF2,ZNF248,NETO1,CPNE4,JPH3" MicroRNA hsa-miR-329:mirSVR_lowEffct hsa-miR-329:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.13E-158 5.13E-154 3.23E-156 2.97E-155 408 1724 "VWA5B2,KCNH8,CLK4,FAM43B,ARID1A,CSMD3,CCDC85A,ADD1,KIAA1211,KIDINS220,CC2D2A,TAOK1,SMIM17,SEMA6A,ALCAM,ABCD2,DPP10,FGD2,PPFIA4,PKP4,APBA2,FAM131A,PHYHD1,SHROOM2,NCOA1,NUMB,DDX3Y,INSYN2B,ATM,ATP2B2,SLC2A11,CADM3,NOL4,MYOM1,ADAM15,BACH1,SNAI3-AS1,BBS2,NRP2,CFLAR,BMP7,FUBP1,NAE1,BTK,GYG2,BAIAP3,CFAP410,CACNA2D1,CACNB2,KALRN,CAMK2B,CLDN10,LDB2,METTL6,USP6,LRBA,CDC42,CDH10,L3MBTL4,IGFN1,NOG,NUMBL,CACNA2D2,LSMEM2,KIAA1549L,HECTD1,NIPBL,AKAP7,AHCTF1,RTTN,CREM,CRY2,HINFP,SLC32A1,ANKRD44,FEZ1,CSNK1E,SUSD5,PLXNA4,SLITRK5,DZIP3,ERC2,CFAP61,CTNND1,ST18,NOS1AP,FRMPD4,RASSF2,MATR3,TOMM20,SPOCK2,YTHDC1,ZBTB24,HP1BP3,COPS7A,MED24,PLPPR4,SNAP91,SACS,SV2A,SRGAP3,AK5,G3BP2,WDR20,CHRDL1,DLG2,EXOG,GRIN3A,DMD,DMPK,CASP8AP2,PDCD6IP,DTNA,ABCC5,ABCC9,CNNM1,SEMA3D,RBM12,APH1A,KMT5B,EGR3,C3orf18,EN2,EPB41L2,DMTN,GPHN,ERBB2,DENND4A,NSRP1,DLC1,OLFM1,PCYOX1,SYNCRIP,AGAP3,RGPD5,FOXO3,COQ5,SMC2,FAM49B,NPTN,ARFGAP2,ZNF605,ERGIC3,NSG2,CELF1,DACH2,CGREF1,NSG1,STAU2,ABLIM2,TVP23A,CHL1,GAD2,GALC,NCKAP1,TMEM8B,ATP8A2,ACSS1,CPLX2,MYOZ2,SESN1,GGT5,BRD8,TXNL4A,TCERG1,PCDH11X,CBX1,ZNF782,GPT2,ADGRA3,PRUNE2,CCDC184,MCHR1,GPR34,RAPGEF1,GRIA2,DIDO1,GRIA4,GRIK1,GRIK2,GRM5,RNF165,GSTM5,AP4S1,WIF1,ARHGAP19,MIER3,OPALIN,HSD17B1,IRF8,MSL1,RBPJ,DOCK7,IL11RA,ITPKB,KCNH2,KIF2A,KIF5A,KLC1,STXBP5,LAMP2,LMO2,SYTL4,NCOA7,MAOB,MAP2,MARK3,MAT2A,SYT9,CHIC1,LDLRAD3,MEIS1,MGAT3,MRPL42,MDGA1,LYRM9,MYO7A,MYT1,NAP1L3,P2RY13,NCAM1,NEK1,NHLH1,NOVA2,SMIM11A,NUCB2,NUMA1,TBC1D25,OPCML,P2RX7,GPR137C,PALM,CNTN3,PBX1,PCMT1,PCSK2,PDCD2,PDE3A,SSH1,NALCN,CAMKV,PIK3R1,PRIMPOL,CDIP1,RC3H2,LRP12,EPB41L4B,TNPO2,FAT3,POU3F2,PPM1B,CRLS1,RASGEF1B,MAPK4,PROX1,PRPSAP2,BCAS3,VPS13C,PTCH1,UHRF1BP1,PTPRD,PTPRO,RAD17,SH3TC2,ATG16L1,ZNF493,RADX,KHDRBS2,ZDHHC14,REV3L,RFX3,RGS7,PRIMA1,RNF220,RIC8B,RPRD1A,RNH1,EPHA10,SGSM1,ST6GALNAC6,RTKN,ZNF331,DGLUCY,ATXN1,FNIP1,CASC3,MRAS,TRA2B,FAM102A,NTNG1,SEC31A,DZIP1,ZNF365,KANSL3,SLC6A11,SLC8A3,SLC12A4,NAPB,TMEM132D,ELMO2,SLC20A2,SLCO1A2,SLC22A4,CDK5RAP2,MYH15,SMARCE1,RCOR3,IFT122,INAVA,UNC80,FAM219A,WDTC1,TRERF1,SOX5,ZCCHC24,KIF21B,BDP1,ZSWIM8,LHFPL4,SPP1,KDM4C,ZC3H13,KIF1B,NPAS3,POGZ,ITPRID2,EPB41L3,ZC4H2,MAPK8IP3,MPRIP,SEPT8,TTBK2,SULF2,AJAP1,ZC3H4,SYNE2,VAMP1,SYPL1,SYT1,COBL,C12orf76,CAMTA1,MLST8,TAL1,ADGRL3,AGTPBP1,TBL1X,ANO4,TBX15,SIN3B,DMXL2,ZFP90,TPCN2,USP22,AZIN2,SYNE1,NAT16,PCDHB9,TNS2,HIF3A,CYB561A3,CRB1,ITGB3BP,SLC44A1,TIE1,TMEM9,TLR4,BEX4,TP53BP1,TPM3,ZNF346,PRMT8,PDSS1,NEIL2,TRPS1,SSBP2,CADM1,EIF4ENIF1,LMF1,XPO1,ZNF711,ZNF24,TRIM9,FMN2,LYPD6,TCEAL7,TMEM237,FSTL5,PLPPR5,SMARCAD1,WNK1,PRDM2,LINC02210,RNF103,HPS4,PCDH15,KCNAB1,CAB39L,WIPF2,CAMK1G,VANGL2,MSRB3,TTC7A,SLC39A12,FRMD6,IFT88,NETO2,ST8SIA2" MicroRNA hsa-miR-148b:mirSVR_lowEffct hsa-miR-148b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-157 6.76E-154 4.22E-156 3.89E-155 421 1835 "KCNH8,ASIC1,ACHE,NCKAP5,CSMD2,ADARB2,ADCY2,ADD2,PLEKHH1,GRAMD1B,USP31,PWWP2A,DPY19L2P4,OLMALINC,MTA3,SLC24A4,PCDH19,OSBPL1A,CC2D2A,HFM1,LRRC7,SRPX,ARHGAP20,GOLGA7B,SYT13,MRTFA,ZFAT,OGT,DPP10,ANK2,CCDC146,APC,EPB41L5,TNRC6C,SHTN1,SFMBT2,PDXK,CDK13,MARCH3,CAPRIN2,NUMB,ASTN1,DDX3Y,ATP2A2,ATP2B3,MTMR9,BACH1,MPDZ,BCL2L2,KSR1,SYNJ2,BSN,DDR1,CALM1,KALRN,CAMK2A,LDB2,USP2,P2RX6,SEPT7,CDC25B,TIGD7,TBRG4,KMT2C,ZFYVE9,CLCN3,KIAA1549L,NRXN1,CLTC,FBXO7,FAM189A2,TJP2,FADS2,NIPBL,CNR1,IQCK,PCYT1B,AKAP6,LETMD1,ABI3BP,IFFO1,CHD1L,SLC35F1,PREPL,CRY2,CS,CSF1,PDE4DIP,PLXNA4,PPP1R16B,APPL1,PHF14,RIMS2,CCDC144A,KATNAL2,DCAF8,TBC1D5,IST1,ARMCX4,ARMCX2,HEPH,ELMO1,HP1BP3,CEP170,RHOBTB1,G3BP2,HS3ST2,USP3,DNAH9,SLC29A4,CDON,DMTF1,SLC12A6,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,DYRK1A,ABCC5,E2F5,WDPCP,EDNRA,EDNRB,HEYL,EGFR,MBNL2,KMT5B,AASS,EIF4G2,PAN3,EPB41,EPB41L2,MTSS1L,EPHB1,GPHN,SLC43A2,STX2,EFS,TAOK3,ATP8A1,ST3GAL6,FCGRT,AMOTL2,SCARA3,SEC23B,FOXF2,SEMA4D,NOP56,NBEA,TACC2,POMT1,PDLIM5,ZNF605,NRG3,GABRB1,GALNT15,GALC,SIGLEC8,SEPT9,WASF3,ALDH1L1,TUBGCP4,SPIN1,GLS,TOX3,AIFM3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,RAPGEF4,TPPP,ADAMTS13,SERP2,GRM2,GRM7,ZNF496,LINC01089,FAM19A2,PTPN5,TMEM25,MFSD2A,RNFT2,RASSF8,FRMD5,HLF,SYNPO,HNMT,TLX1,AGFG1,HSP90AA1,HTR5A,ICA1,ZNF546,IGF1,C5orf24,INPP5B,LRRTM3,JAK1,SLC35G1,KCNH1,KCNJ16,KCNK1,KLRC2,VWA5A,PIK3AP1,ZFYVE27,MAP4,AQP11,MBP,CHIC1,MDM4,MEIS1,MKLN1,MMP16,ERICH3,PTOV1,MTR,NEXMIF,NACA,NAP1L1,NCAM1,ZC3H12B,RCOR2,NELL1,NELL2,NFYA,NOVA1,NTRK2,NUMA1,TBC1D25,OPA1,OPCML,OPHN1,P2RY1,ZDHHC22,SNTG1,DPY19L2P2,PCSK5,PRTG,PDE2A,PDE3B,PDE4B,PDE4D,PIRT,PDGFRA,PIK3R1,SNX10,GPSM2,NLE1,FTO,MTRF1L,PRIMPOL,LRP12,ING3,MBOAT7,SH3KBP1,MED1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,EPDR1,HYDIN,MASP1,SLC22A23,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,PLEKHB2,ATG16L1,ROGDI,RBBP8,PRRT2,RFX3,RGS12,SEC61A2,RIC8B,ZNF532,TMEM206,UEVLD,BAALC,ZC3H14,CLIP1,RTN1,FAM192A,SEMA6D,SATB1,CSRNP3,SCN2A,SCN2B,SCN8A,SCNN1D,SELL,MRAS,SUPT20H,TRA2B,RASA3,NLGN4Y,PPP1R9A,MYO18A,AMBRA1,FNDC3A,SLITRK3,SYBU,SLA,EPN2,KANSL3,PKNOX2,SLC8A1,ARHGEF40,CCDC88A,TRIM67,SHANK2,BTBD7,ATF7IP,CPEB4,RCOR3,IFT122,SNAP25,SNCA,KIF13A,MYO16,PDZD2,BDP1,EMC1,KDM4C,TEX2,CLASP2,CLSTN2,ERBIN,INKA2,STAU1,CEP68,DIP2A,STXBP1,AJAP1,PRRC2C,C3orf70,PLCB1,TMEM150C,SYT1,C12orf76,TACR1,TAF9,EXOC7,AGTPBP1,FBXW11,TMEM136,EHBP1,TCF4,ZFP90,TCF7,AZIN2,DOCK9,PHF24,PCDHB4,ARHGEF12,GPRIN3,DICER1-AS1,LEFTY2,HHIP,GZF1,MTMR14,NR2E1,HEY2,R3HDM1,C5orf64,RBFOX2,CDK20,SYNPO2,METTL3,TRPS1,ZMYND8,HIRA,UBE2H,UGT8,SLAIN1,OSBP2,FLRT2,ZNF709,BCL2L13,VAV2,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,SLC26A10,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,CADM2,PRDM2,SLC38A1,RGMA,XKR7,PCDH15,SNX27,KCNAB1,FAM47E,WIPF2,SLC17A6,PARP11,UBE3B,KAT6A,CASC15,CERS6,ZNF248,SLC39A12,SLC4A10,FAM198A" MicroRNA hsa-miR-93:mirSVR_highEffct hsa-miR-93:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.26E-157 1.83E-153 1.14E-155 1.05E-154 394 1614 "KCNH8,NCKAP5,SORCS1,SLC24A4,KIAA1324,ABCD2,MRTFA,SEMA7A,USP28,SUGT1P4-STRA6LP-CCDC180,APP,SHTN1,AQP4,LINC00173,STK33,CAPRIN2,RASL11B,ASTN1,ATM,ATP1A2,SLC4A4,ATP1B3,ATP2A2,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,NRP2,MTMR3,JAZF1,CALB2,MAP7,PRC1,CBR1,USP6,C1orf52,TIGD7,CFL2,CHGA,MS4A7,TAOK2,EPS15L1,IGFBP7-AS1,ZFYVE9,ABCG2,C4orf33,ARMC8,SLC25A27,AKAP5,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,GREB1,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,G3BP2,OLIG1,USP3,DMTF1,DPYSL2,DRD1,FAM78B,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,EDN3,ANKRD46,EFNA3,FAM13A,SUGP2,KMT5B,EGR3,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EML1,EPHA5,DNAJC27,KATNAL1,EZH1,F3,F8,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,FGFR1,SUCO,SEMA4D,FLT1,NBEA,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,ZMAT1,GABBR1,GABRA1,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,ADAM28,RAB30,TNRC6A,KDM2B,DCLK2,RAB40B,TDRKH,GPR37,RAPGEF4,DIDO1,GRM7,CIT,LINC00839,TMEM25,AP4S1,IRAK3,HAS2,HPS5,MIER3,HNRNPK,HTR5A,MSL1,DOCK7,ITGAV,JAK1,METTL21A,OLFM3,KCNJ10,KCNJ16,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,NCOA7,SMAD1,MAN2A2,MAP6,MAT2A,AQP11,MDM4,LRP1B,SRSF12,KITLG,MID1,POC1B,XRRA1,MOG,CCDC80,MSR1,MXI1,MYCN,MYH6,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PRRX1,RETREG2,EPB41L4B,DRAM2,CRLS1,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,PXK,PTPN13,PTPRD,RAB5B,CEP97,USP47,ATG16L1,FAT4,ZNF493,OXR1,RASGRF2,ARID4A,ZYG11B,REV3L,GTDC1,SLC25A36,PBRM1,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,LRFN5,HOGA1,SCN2A,SCN3A,FAM19A1,SOX6,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,ZC3H13,IQSEC2,ZBTB43,NPAS3,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,NKAIN2,ERBIN,RGL1,ADHFE1,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,WDR7,SYNE1,RALYL,FAM189A1,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,PRMT8,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,CELF4,ZSCAN26,ANKS1B,LAMP5,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,PCDH15,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,DPF3,SLC4A10" MicroRNA hsa-miR-320e:mirSVR_lowEffct hsa-miR-320e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.41E-157 2.48E-153 1.53E-155 1.41E-154 432 1936 "KCNH8,ABR,TKTL1,ARID1A,XKR4,CSMD3,ADAR,CCDC85A,ADD1,UNC5A,RNF150,KLHL13,PCDH19,OSBPL1A,KIAA1324,WDR35,SEMA6A,BCAR3,AMT,SEMA7A,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,GPAM,ALS2,PHYHD1,SHTN1,LGR5,MIER1,SFMBT2,CASK,SPTBN4,ARHGAP5,ARNTL,CAPRIN2,BRINP2,ZBTB10,RASL11B,ASTN1,TMEM108,STX16,SLC2A11,NOL4,LINC00847,NRP2,KSR1,DDR1,CALB1,CABP7,CALM1,KALRN,PTBP2,CAMK2A,CANX,MAP7,RUNX1T1,NFS1,LDB2,METTL6,CD86,ENTPD6,C1orf52,SEPT7,CDC42,CDH10,DCLK1,CCPG1,IGFN1,CLGN,NOG,CACNA2D2,SRSF11,NRXN3,DNAJB5,NIPBL,CNTN1,AKAP7,AKAP6,SUMF2,COL11A2,SLC4A8,CHD1L,C2CD2,RBM39,HAPLN1,ANKRD44,FEZ1,MICAL2,SUSD5,ATRNL1,CST3,DZIP3,GREB1,ST18,RUBCN,FAM131B,KATNAL2,DGKG,DAPK1,DBN1,DCC,ELMSAN1,DGCR5,ZC3H11A,RHOBTB1,SV2B,ZNF582-AS1,HS3ST4,SLC29A4,SLC12A6,FAM57B,ACOT8,DTNA,DYRK1A,FARSB,DNM1L,GOLT1B,CNNM1,HEYL,PHF20L1,EGR3,ASB3,SORBS3,TENM1,CERCAM,ELAVL4,BSCL2,PAN3,USPL1,EIF1,EPB41,EPB41L2,DMTN,ANKRD13B,DENND4A,ANKMY1,EYA1,MRVI1,F5,CLVS1,SH3YL1,TMEM132C,SCML2,FCGR1A,SLC9B2,SEC23B,FLNC,TACC2,HVCN1,FAM49B,ATP2C1,CELF1,STAU2,KBTBD12,OGA,FYB1,ZNF44,DENND2A,GAD1,BRPF3,ZNF234,ZNF274,IP6K3,GAP43,DNER,GATM,ALDH1L1,ARFIP1,GFAP,GFRA2,ZNF276,ZNF638,INSM2,POLL,DCLK2,GPD2,GPR12,TMEM121B,PCLO,GRIA2,PLCD4,GRIN1,GRM2,KIF3A,GSTT2,RABL2A,MAP4K5,ATXN2L,MIER3,HMGB1,HMGCL,AGBL5,ZNF491,ZDHHC15,OPALIN,HSP90AA1,SMAP1,FAAP20,MSL1,SOWAHA,USP54,IL6R,SLC35G1,KCNA6,KCNC2,CLVS2,KCNJ10,KCNK3,KCNMA1,KHK,SYTL4,NCOA7,MAP4,MBP,SYT9,MID1,AFDN,MMP16,MOG,MPP2,CCDC80,BLOC1S2,NRBP2,N6AMT1,NACA,NAP1L1,NAP1L2,NCAM1,ZC3H12B,NDP,NEFM,NEUROD1,CNOT4,DNHD1,TBC1D25,GPR88,CHAMP1,OPA1,OPCML,SNTG1,ETFRF1,PCDH9,PCMT1,PDE4D,PIRT,PDGFRA,ENPP2,PFKFB2,NLGN3,TMIE,SNX10,ZFYVE21,TMEM38A,GPSM2,JAKMIP1,PMP22,RC3H2,SDK2,SLC36A4,PILRA,TNPO2,PPM1B,PPP3CA,VSTM2L,MAPK3,GRAMD1C,MASP1,SLC22A23,APTX,MDGA2,TMEM104,PSMD13,PLPPR1,PTHLH,PTPRD,CASTOR1,PTPRO,ZNF615,TMEM231,RAB5B,TMEM255A,RAP1GAP,ZNF493,RASGRF1,ARID4A,FEZF2,GTDC1,RGS3,RIC8B,RNASEL,C12orf49,ALG9,CARF,YY1AP1,PCMTD2,LGR4,ATAT1,CLIP1,ZNF568,NCBP3,AMER2,SALL1,ATXN2,SCN2A,SFPQ,SCAF8,FAM102A,WDR37,PPP4R3A,SMTN,WDR47,FAM214B,SLC6A1,PKNOX2,LRRC55,SLC6A8,SLC8A2,SEPHS1,SLC12A2,SLC12A4,ELMO2,SLCO1A2,NAXD,COA1,CDK5RAP2,RIMS1,TMCC1,USP33,DOP1A,MYT1L,SOX11,NMNAT2,SPTB,NFASC,LMO3,C11orf87,TAB2,ZNF302,SMOC1,NXT2,NCDN,ZSCAN29,SEPT8,DIP2A,KANK1,GANAB,SEPT3,SYNE2,VAMP1,ARHGEF9,SYN2,TAC1,TACR1,ANKRD12,MTCL1,MLST8,CNTN2,IQCE,ATMIN,TCF4,DMXL2,TRIM2,SYNE1,AKNA,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,DICER1-AS1,ITGB3BP,AP4E1,ARL10,ENHO,TK2,FAM124A,PIK3R5,RBFOX2,NPL,NR2C2,TRH,PDSS1,AMACR,KCNE5,TTTY15,RFTN2,FAM155A,FRRS1L,MEAF6,VLDLR,RBFOX3,WIPF1,XRCC4,PCDH20,ZIC3,TRIM9,PLPP4,MKRN3,TMEM237,FSTL5,PCBP1-AS1,SMARCAD1,MEIS3,SLC30A4,PRTFDC1,NT5M,EVI5,STOX2,PRDM8,RNF103,HPS4,PCDH15,URM1,PARP11,RGS7BP,CAMK1G,CERS6,JMJD1C,NLRP3,ZNF248,TIGD6,NHSL1,SSPN,NETO1,ST8SIA2,SLC4A10,SENP7" MicroRNA hsa-miR-1226:mirSVR_lowEffct hsa-miR-1226:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.19E-157 4.04E-153 2.48E-155 2.28E-154 427 1895 "VWA5B2,RALGAPA1,SERPINA3,ABAT,ASPHD1,ASIC2,SYS1,ACTN2,KDM5D,CSMD3,NDRG2,ADD1,SLC12A5,CDC7,PLEKHH1,PWWP2A,KIAA1211,INTS2,HACE1,OSBPL6,AK2,MARCH4,UNC79,FAM135A,AMPD3,DPP10,ANK2,EP400,C6orf89,MAP4K3,CNIH2,APBA2,EPB41L5,DGKZ,FAM131A,VAT1L,LGR5,MIER1,PDXK,SPTBN4,ZFYVE28,ARHGDIG,ARNTL,ASPH,DACT3,PCDHGB4,ATP2A2,NOL4,ATP6V0A1,LINC00847,DCAF5,GPR146,KSR1,ARHGEF7,BTK,CACNA1G,C5,GPC2,MMD2,CFAP410,CA12,CACNA1A,CACNA1E,CACNB2,KALRN,HAP1,PTBP2,CAPN3,HIP1R,ARHGEF25,CBR1,CBS,CD86,CD38,ENTPD6,CDC42,LRRFIP1,LARGE1,IGFN1,GPR37L1,SRSF11,CASC2,SYNPR,CNOT8,LSMEM2,COG1,FBXO7,TJP2,FADS2,MAP4K4,IGLON5,BTF3L4,TOGARAM2,CHD1L,RBM39,CRMP1,GDA,ABCG1,AATK,SNCAIP,CSF1,RGS6,FEZ1,OSBPL3,SIPA1L1,VAC14-AS1,PDE4DIP,PPP6R2,DCAF4,ECE2,NOS1AP,ZFYVE16,ZNF337,IST1,TMEM170A,SPATA2,CNIH3,TIAM2,RUSC2,GSDME,RHOBTB1,SRGAP3,TMCC2,DLG2,DLX1,CD99L2,TRAPPC9,DNM2,DMTF1,DTNA,TOM1,DNAJB6,PHC2,SIDT2,GPR61,ABI2,ELAVL2,ELN,CALCRL,LRRC17,RASGRP2,SEZ6,ENPP6,ANKRD13B,STX2,SRRM1,ERBB2,ZNF549,DNAJC27,RASL12,SIRPB1,KATNAL1,REEP2,TUBB3,EFEMP1,DLC1,ST3GAL6,CHST15,TOMM40L,FER,FGFR1,CAP2,PCYOX1,SYT3,COQ5,SORBS1,POMT1,HVCN1,TVP23A,DKK3,MEGF10,GALC,B4GALNT1,ARPP21,ZNF274,DISC1,GCNT2,TUBGCP4,SULT1C4,PPARGC1A,TXNL4A,GLYR1,TOX3,POLL,DCLK2,LOXL3,GPD2,MCHR1,GPER1,CECR2,RAPGEF4,ATP2B1-AS1,GRIA1,PLCD4,NR3C1,ZNF496,ZBTB49,MFSD2A,MUM1,MAEL,NXPH3,FRMD5,SYNPO,TLX1,HSD17B1,FAAP20,IDH3B,GAREM2,ZIC5,SLC6A17,NME9,ITGA7,JAK2,KCNA6,KCNB1,KCND1,KCNJ10,KCNJ11,KCNK1,KCNMA1,KCNN2,STXBP5,MAP6,SYT9,MDM4,SRSF12,PPM1L,MITF,XRRA1,CPNE9,MT3,MYO7A,MYO9A,BEX5,NAP1L1,FXYD6,SFR1,NEFM,CCDC13,NEUROD2,NFE2L2,NME4,NTRK2,NUCB1,OPA1,OPRL1,ZDHHC22,SNTG1,PAK3,PBX1,PCDHGC3,GDAP1L1,SSH1,NALCN,PLCB2,FTO,PLP1,PLXNB1,LRP12,PSAT1,EXOSC10,PRRX1,ING3,SEPT4,FAT3,POLG,POLR2F,PCDHB17P,PTPA,NDUFS7,SLC22A23,WBP1L,GON4L,WDR25,PSMD13,PIGG,PTCH1,ANKHD1,UHRF1BP1,PTHLH,TMEM260,PTPRD,CASTOR1,PTPRO,FAM120C,PEX5,TMEM255A,FAM66C,ZCWPW1,RADX,SLC6A15,TRIM68,RGS12,ARHGEF10L,RIC8B,RNASEL,C12orf49,CYB561D1,ROBO2,TMEM100,MCMBP,SGSM1,PRR5L,HSD11B1L,WLS,RTN1,ZNF568,ZNF331,SALL1,SBF1,FAM19A1,CASC3,MRAS,FAM102A,MYO18A,MAGI3,FNDC3A,SLITRK3,RPH3A,BTBD3,SMTN,SLC6A1,PKNOX2,ZNF430,SLC9A5,SLC14A1,ARFGAP1,SMARCC2,SNCA,SNRPN,FAM126B,UNC80,DOP1A,WDTC1,IZUMO4,IDI2-AS1,CLASP2,TROVE2,SSTR2,LRRC4,ERBIN,INKA2,MPRIP,CEP68,RGL1,DIP2A,SEPT3,JMJD6,SYNE2,TMEM150C,SYP,MLST8,DNMBP,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,NAT16,PCDHGA1,AKNA,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,DICER1,ZFPM2,CRB1,SPX,ITGB3BP,MTMR14,TMEM9,TLR4,ERCC6L2,TMOD1,SEZ6L,TPD52,TPM1,WBP2,TRO,RUSC1,LRTM2,ZKSCAN5,UBTF,GORASP1,OSBP2,BCL2L13,WIPF1,SLC13A3,LGI4,ZNF711,ZNF24,ZNF74,NDRG4,SLC26A10,EML6,SH3GLB2,DHX33,DNALI1,GDPD5,LINC02210,ADAMTS9,SEMA3B,SIGLEC10,WIPF2,MVB12B,CASC15,ADAMTSL3,ZNF248,TTC7A,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-4302:mirSVR_lowEffct hsa-miR-4302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-156 6.94E-153 4.23E-155 3.90E-154 436 1976 "RALGAPA1,DGCR6,ASIC2,ACHE,CLK4,TKTL1,ACTN1,CSMD3,NDRG2,PSMG3-AS1,SLITRK1,SORCS1,UNC5A,SLC24A4,PCDH19,HACE1,KIAA1324,DISP3,AK2,SEMA6A,ALCAM,BCAR3,ALK,SYT13,PITPNM2,ANK3,FGD2,CCDC146,PPFIA1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,GPAM,APP,PDXK,CASK,TMEFF1,SPTBN4,ARRB2,ASCL1,ASPH,BRINP2,ASTN1,ATP2B2,N4BP2L1,DPY19L3,ATP6V0A1,ADGRB2,BCL2L2,BCS1L,PROM1,WASF1,MYRF,CA8,DDR1,CACNB4,CALB1,CBLN1,CBR1,CCK,CCNH,RGN,SYNGR3,ENTPD6,LRRFIP1,EVI5L,LGI1,CCPG1,CBARP,CHM,CASC2,CNOT8,KMT2C,ABCG2,SRP14-AS1,MAP4K4,PCYT1B,FAM149A,AKAP6,SUMF2,AHCTF1,IGDCC3,HS3ST5,CPS1,TRIM69,RGS6,SEC24C,ARHGEF10,MICAL2,APPL1,GREB1,CTNND2,PUM1,CYBB,BOC,GAPVD1,DCAF8,ZFYVE16,ZNF337,RIMS3,DGKB,BRINP1,AIF1L,DCC,SPATA2,ZEB2,HEPH,KIAA0753,MAGI2,GUCD1,PLPPR4,PARD6A,SPOCK3,RABGAP1L,SEC16A,KBTBD11,DLG3,CPEB2,FAM57B,ACOT8,PDCD6IP,DTNA,ABCC5,ABCC9,EDN1,FAM135B,EDNRA,EDNRB,SYT15,HEYL,PHF20L1,MRO,TMEM132E,EIF4G2,EMX2,EN2,EPB41,LRRC17,CDHR1,CEND1,EZH1,F5,SH3YL1,ZIC4,TAOK3,DLC1,RACK1,FCGRT,FDFT1,TESK2,KAT8,GORAB,BAIAP2,PRKAG2,POLK,SUCO,MEX3B,SYNCRIP,FLNC,TACC2,HVCN1,TRIM16,NPTN,ARFGAP2,DACH2,NSG1,NRG3,ABLIM2,GABBR1,GABRA1,DENND2A,HBS1L,BRPF3,ARPP21,NCKAP1,GCK,ALDH1L1,ADAM28,GGT7,TCERG1,GLI2,TOX3,GOLGB1,PCLO,GRIA2,GRID1,GRM1,GRM7,GSTM5,ZBTB49,BVES,AP4S1,LINGO1,PSIP1,FAM107A,ADAMTS6,WIF1,HPS5,MAN1B1,MIER3,ELOVL5,HNMT,TCEAL6,LRRC75A,HTR2A,ICA1,ZIC5,PLD5,LIX1,JAK1,OLFM3,KCNJ3,KCNJ5,KIF5C,KLC1,KTN1,STMN1,SYTL4,NCOA7,MAP2,MARK3,MBNL1,SYT9,LDLRAD3,MDM4,SHC3,PPM1L,MOG,ERICH3,CCDC80,BLOC1S2,MYCN,LYRM9,MYO7A,MYO9A,NEK1,NFYA,CNOT4,DNHD1,SLC11A2,NTRK2,NTRK3,IGSF11,GPR88,OMG,GLIPR1L2,PBX1,ETFRF1,PCMT1,PIRT,PDGFRA,ENPP2,SLC10A4,GPR85,PFKFB3,NALCN,FAM218A,A2ML1,NLE1,PCDH18,SMIM7,NECAB2,ING3,DRAM2,PPM1B,TATDN3,PPP2R2B,CRLS1,MAPK7,MAPK9,HYDIN,BCAS3,SLC22A23,SIDT1,GON4L,QRICH1,PIGG,PTCH1,BDNF-AS,PTHLH,STK32A,PTX3,ZSCAN2,ZNF615,TMEM231,RAB5B,TMEM255A,SLC25A48,RALGDS,FAM184A,RBBP6,SLC6A15,MORC4,FIGN,ARHGEF10L,RNF220,ROBO1,CCDC25,PCMTD2,FBXW7,RPS6KA2,MAP6D1,HSD11B1L,CLIP1,TRAPPC13,ATXN7,HOGA1,SCN3A,SCP2,ASIC4,SOX6,TRIM46,GALNT10,KIF21A,FERMT1,KIF16B,CPEB3,NTNG1,AMBRA1,R3HDM2,CNKSR2,CCDC92,ST3GAL3,ABLIM3,SLC1A3,ARHGEF40,SLC12A4,SCMH1,BTBD7,SLC20A2,SORCS3,SMARCD3,RCOR3,PALLD,MYO16,SOX5,SOX10,ZSWIM8,SP4,CAND2,TSPYL2,RBM26,DDN,LMO3,ITPRID2,SSTR2,EPB41L3,LRRC4,ZSCAN29,CEP68,DIP2A,STAC2,ADHFE1,AJAP1,GSE1,FGD4,PRRC2C,ZFR2,TMEM150C,ARC,SYPL1,COBL,TAC1,TACC1,TACR1,CAMTA1,CAMSAP2,PDLIM2,KLHL4,ANO4,VWA3A,EHBP1,TCF4,ZFP90,ZEB1,TRIM2,TMEM151B,ARHGEF12,USP32P1,TEK,SIRT1,CRB1,LEFTY2,AP4E1,HHIP,TJP1,BHLHB9,HEY2,BEX4,PRRT1,TNR,TPD52,TPM1,C9orf85,TRH,PPIL6,RUSC1,TSC1,HIRA,SGK3,CADM1,FAM155A,SLAIN1,PLEKHH2,ZNF709,MGAT5B,PLPPR2,CCDC136,NSD2,WRN,CLDND1,XRCC4,LGI4,ZNF19,ZNF28,TRIM9,ZNF540,NDRG4,CRB2,MKRN3,ZNF138,CELF4,AMZ1,ZFAND5,SYNC,STOX2,MDH1B,TRIM16L,DOCK8,HNRNPA3,ADAMTSL3,TIGD6,RNF170,MSRB3,SLC4A10,JPH3" MicroRNA hsa-miR-376a:mirSVR_lowEffct hsa-miR-376a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.17E-156 1.22E-152 7.40E-155 6.81E-154 393 1614 "NBAT1,XKR4,ADAR,GALNT13,ERMN,RNF150,NLGN4X,ZNF608,AGT,RTL9,KIAA1324,CC2D2A,PLA2G6,C1QTNF1,ALCAM,BCAR3,FAM135A,GPRASP2,TRMT9B,PITPNM2,ANK3,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,MAGEE2,DGKD,AMER3,USP37,ARHGAP5,DACT3,ZBTB10,NUMB,ASTN1,TMEM108,ATM,SLC4A4,ATP2B3,MTMR9,N4BP2L1,DPY19L3,CFLAR,BMPR1B,DST,SYNJ1,LINC00906,MTMR2,CACNA1E,CACNB2,KALRN,PTBP2,SPAG9,NFS1,ENTPD6,CDH2,DCLK1,ZMYM4,LRRFIP1,CDH18,LOC730101,CHN2,CHRNA4,B4GALT6,RAB33A,ZFYVE9,CLCN3,SRP14-AS1,HECTD1,TMEM155,FHL5,CNN3,ARMC8,SUMF2,RTTN,ZNF521,NRG2,PREPL,CREM,NCOR1,CLIP3,CSF2RA,ARHGEF10,MICAL2,CNTNAP2,DZIP3,CMTM5,PHF14,CTH,PUM1,ST18,FAM131B,DCAF8,FRMPD4,ZNF337,PABPC5,DNAL1,JAKMIP2,CEP170,MAGI2,DDX46,SPOCK3,SRGAP3,ARNT2,DLG2,DLX1,GRIN3A,DMD,NR1D2,DOCK2,DRD1,ACOT8,CNNM1,SEMA3D,FRY,YAF2,FAM13A,KMT5B,ABI2,AASS,EIF4G2,EIF5,PLEKHA1,RGS17,CALCRL,EN2,VPS13B,LRRC17,DENND4A,RTN3,EXTL2,F5,TUBB4A,SCML2,EFEMP1,ST3GAL6,ZSCAN30,SEC24B,FER,FGF1,FGF14,FGFR1,SUCO,UBE2E3,FOXG1,PCYOX1,FLT1,NOP56,UFM1,PDLIM5,NPTN,DACH2,MSANTD4,MEGF10,GAB1,CHL1,GABRG1,GABRG2,BRPF3,IQGAP2,DISC1,ATP8A2,KIAA1841,FAXC,MSTN,PCDH17,PPARGC1A,GK,GLI2,GLS,MSL3,INSM2,LUZP2,GNAS,GPD2,ATF7,LILRA2,GPR12,GRIA2,GRIK3,SERP2,ATE1,GRM3,AP4S1,LINGO1,PSIP1,MAP4K5,CELF3,MAEL,C1orf94,NEGR1,OPALIN,NKD1,RBPJ,LRRCC1,PLD5,HES5,IL6ST,INPP5B,JAK2,SLC35G1,KCNK2,KIF5C,LIMS1,MATN2,MBP,CHIC1,MEIS2,MEST,KCTD6,AFDN,ZNF680,SAMD5,BLOC1S2,MSR1,MSRA,ZNF92,MTTP,MTR,RSPO2,NEXMIF,ZC3H12B,NEUROD1,NFE2L2,NOS1,NPTX1,NTRK2,GPR137C,PAH,PAX6,PCDH8,PCSK5,ENPP2,PDYN,NALCN,PIK3C2A,PIK3R1,A2ML1,ZFYVE21,XRN1,ST8SIA5,PLCL1,PLIN1,PURG,PDZRN4,STRN3,RETREG2,SLC36A4,FAT3,PPARA,PTPA,RASGEF1B,PRKCB,DIRAS2,BCAS3,PTCH1,ANKHD1,PTN,FAM120C,PEX5,TUG1,TMEM255A,SH3TC2,RAP1GDS1,ENOX1,OXR1,MSANTD2,REV3L,RFX3,RGS12,RIC8B,RNASEL,LGI2,ARMC5,CARF,CCDC102B,FBXW7,ZC3H14,ADAL,CNTNAP3,MEG3,HUNK,ATAT1,ZNF354C,CCDC112,DGLUCY,SATB1,LRFN5,SCP2,FNIP1,IL17RB,SFPQ,SCG5,KIF21A,PPP1R9A,SH3GL3,PPM1E,FNDC3A,R3HDM2,NLGN1,CTXN2,DZIP1,BTBD3,SLC8A3,ZNF334,SLC15A2,CPEB4,ZFP1,SMARCC2,ANKRD36,SNRPN,PALLD,FAM126B,SON,WDTC1,TRERF1,ENKUR,C11orf87,CLASP2,TROVE2,STOX1,MAPK8IP3,CEP68,TTBK2,ADHFE1,KANK1,SEPT3,STXBP1,KLHL7,FGD4,PLCB1,SYN2,SYPL1,TAC1,TACC1,PDLIM2,UNC5D,WWC1,TMEM136,MGRN1,SATB2,TPCN2,RPGRIP1L,RALYL,PUM2,USP32P1,SLC35G2,DICER1-AS1,ITGB3BP,TGFBR3,ZFP91,HEY2,TMOD1,KCTD2,TP53BP1,NPL,STXBP4,TRPC3,TSN,TUB,ZKSCAN5,SGK3,FAM155A,UBE2H,PLEKHH2,XPO1,XRCC4,MICU3,ZNF28,ZNF32,AGMO,FMN2,GPR158-AS1,TMEM237,ZNF177,EML6,ZSCAN26,INTS3,WNK1,SLC30A4,CADM2,LRP8,EVI5,STOX2,FAM47E,FAM13C,AMN1,DOCK8,RSPRY1,RNF170,KLHDC1,NETO1,SLC4A10" MicroRNA hsa-miR-2115:mirSVR_lowEffct hsa-miR-2115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-156 1.31E-152 7.88E-155 7.26E-154 429 1918 "ASPHD1,NCKAP5,XKR4,ADCY5,GALNT13,ADD3,SORCS1,ADORA1,ADORA2A,UNC5A,KIAA1211,KIDINS220,NLGN4X,MTA3,OSBPL6,ZNF578,TAOK1,USP35,ALCAM,SRPX,MARCH4,FAM135A,PDZD4,AMPD3,AMT,SUGT1P4-STRA6LP-CCDC180,APAF1,ALS2,PPFIA3,PDXK,SPTBN4,RGS20,ARRB2,ASCL1,CAPRIN2,CHRD,NUMB,SLC4A4,DPY19L3,BACH1,SNAI3-AS1,ADGRB3,RGS9,DNAJC27-AS1,DST,SYNJ2,RAB29,BTRC,CA8,CA12,CACNA1A,CACNA1E,CACNB4,PTBP2,TRIM41,VXN,CAST,NFS1,PRC1,CD86,AP4M1,ARHGEF2,DCLK1,CDH18,LOC730101,CDO1,CDR1,CCPG1,CHGA,CHN2,MS4A7,IGFBP7-AS1,ZFYVE9,TPP1,TJP2,SULT4A1,ARHGEF6,SLC4A8,AHCTF1,SMARCAL1,HS3ST5,HAPLN1,CSF1R,IPCEF1,PDE4DIP,DZIP3,KIAA0040,ARHGEF4,USP6NL,CX3CR1,NOS1AP,KIAA0408,KATNAL2,DCAF8,TOX,ZFYVE16,IST1,DGKB,DGKG,DAPK1,AIF1L,ZBTB24,MAGI2,AK5,RABGAP1L,TMCC2,CCDC3,USP3,DOCK2,SLC25A18,ARRDC4,DTNA,EDIL3,HIPK3,SH3GLB1,FAM13A,SUGP2,C3orf18,EML1,DCTN4,LRRC17,EPS8,ERBB4,KATNAL1,PTK2B,CORO2B,ATP8A1,FCGRT,ZSCAN30,PRMT5,KIAA1109,POLR1B,FGF13,MEX3B,FOXG1,CAP2,IP6K2,FLT1,PSD2,TPK1,ARFGAP2,ATP2C1,ZNF605,KHDRBS3,KBTBD12,B3GAT1,TMEM151A,DOT1L,MPP6,MEGF11,GABRA1,HRASLS5,GABRA3,GABRB3,TRAF3IP2,FAM120B,ZMYND11,RAPGEF6,GALR1,ZNF274,ADAM28,USP19,GK,RNPS1,DBF4,GLYR1,GLS,GPM6B,ATF7,FUT10,GPR12,GRIA2,RFFL,CIT,TMEM25,GSTT2,PSIP1,FAM107A,CELF3,RASSF8,HAS2,MAN1B1,ARHGAP19,NCKAP1L,BACH2,HLF,GABARAPL2,SYNPO,C9orf129,ZDHHC15,SHISA6,SMAP1,LINC00667,RAB41,TJAP1,TMEM240,BRINP3,ZNF678,INSM1,ZNF385B,ITGAV,SLC35G1,METTL21A,KCNA1,KCNH2,KCNJ11,KPNA5,CYP27C1,SYTL4,VWA5A,SMAD1,GPR155,MAN2A2,MBP,SYT9,LDLRAD3,MGAT3,SCAMP5,PPM1L,POC1B,AFF1,AFDN,ERICH3,HS6ST3,MYT1,NFIA,NOS1,CNOT4,NTRK3,OPA1,OPRL1,KCNK10,TREM2,PAK3,PCDH9,PCSK5,PIRT,GNG2,PFKFB3,NLGN3,SSH1,A2ML1,CCSER2,XRN1,PLCL1,FTO,PLP1,PRIMPOL,ANKRD16,EXOSC10,RETREG2,SLC36A4,TNPO2,FAT3,POU6F1,TMEM235,CRLS1,PRKAB2,PRKACB,CEP41,MAPK10,GRAMD1C,HYDIN,BCAS3,WBP1L,MDGA2,QRICH1,PIGG,NCR3LG1,TMEM260,ZIK1,PTPRD,EML5,PTPRN2,FAM120C,PTX3,SLC25A48,PLEKHB2,C1orf54,FAM184A,RAP1GAP,SUSD4,ZNF493,RASGRF2,DBX2,BSDC1,SLC6A15,FIGN,RGS7,RGS10,MRPS18A,RNF220,RIC8B,PBRM1,DCUN1D2,GSTCD,MRAP2,NEK11,BAALC,GLDN,ADAL,ABCA11P,HUNK,AMER2,FOXRED2,SALL1,SEMA6D,SATB1,SCN8A,PRCD,SCP2,ASIC4,CASC3,GALNT10,STUM,FOXRED1,MRAS,SCAF8,NTNG1,FBXO11,SLITRK3,WDR37,WDR47,RUFY2,KANSL3,SLC6A11,KDM4D,YPEL4,RAB3GAP1,SLC11A1,ATF7IP,NAXD,MYH15,IFT122,MAPKBP1,MBD5,FAIM2,UNC80,USP33,TRERF1,KIF21B,BDP1,ZSWIM8,CLUAP1,KDM4C,PEG10,KIF1B,ZBTB43,SPART,POGZ,COLGALT2,ITPRID2,SSTR1,LARP4,LRRC4,ST5,MPRIP,NEK4,FGD4,ARHGEF9,FNDC9,COBL,TACR1,EXOC7,TBCEL,IQCE,FBXW11,ANO4,VWA3A,ZEB1,TPCN2,TRIM2,SYNE1,DOCK9,AHCYL2,DICER1,ZNF106,THBS4,TMEM9,TK2,DAAM2,TNFRSF1B,PIK3R5,TPD52L2,ZNF346,SYNPO2,STXBP4,TSC1,RPRM,FRRS1L,PITPNB,PLEKHH2,BEST1,VSNL1,NPDC1,RICTOR,SLC13A3,CFAP298,KCNT2,MKRN3,LYPD6,TCEAL7,ZBTB16,ZNF154,ZSCAN26,SPIRE1,FTSJ1,PLPPR5,ZFAND5,DNALI1,GDPD5,STMN4,TUBA1A,NAV2,WIPF2,PDSS2,RGS7BP,DOCK8,ST7,CASC15,NUP214,TRAM2-AS1,TIGD6,MSRB3,TTC7A,SOCS4,ST8SIA2,SRGAP2B,LAS1L" MicroRNA hsa-miR-624:mirSVR_lowEffct hsa-miR-624:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-156 1.39E-152 8.31E-155 7.65E-154 415 1798 "CPNE2,CLK4,NCKAP5,SYS1,KDM5D,CSMD3,TMCC3,AXIN2,BRAP,PWWP2A,ADORA3,ESYT2,SLC44A5,ZNF608,WDR35,TXNDC16,ZNF578,ADGRF5,LRRC7,ALCAM,CARNS1,MARCH4,PCDH10,GOLGA7B,OGT,ANK1,MAP4K3,CNIH2,BCAS1,SHROOM2,CDC14B,PPP4R4,ASCL1,ASPH,BRINP2,CCAR2,TMEM108,SLC4A4,ZNF583,ATP6V0A1,SYNJ1,ARHGEF7,LINC00906,CASTOR3,PRMT9,GYG2,BSN,WASF1,CACNA1D,CACNB4,CABP7,DIRAS1,CAMK2B,CAMK2G,CH25H,ISPD,NFS1,PRC1,CBR1,ZNF501,NEURL1,CD81,LOC730101,CDO1,COPB2,ASIC3,JAM2,ARHGAP22,PPT2,TPP1,C4orf33,QKI,TMEM155,MAGED1,ABI3BP,TBPL1,ACBD5,ZNF521,ZFP28,CHD1L,CREM,RBM39,CRMP1,GDA,SNCAIP,CSF1,TENM4,LRIG1,CSNK1E,CSNK1G3,SOCS5,FAM169A,CTNND2,RIMS2,CX3CR1,MYADM,ARHGAP32,KATNAL2,DCAF8,TOX,MATR3,KIAA0586,MAML1,TOMM20,SCRN1,DBI,SIRPA,DNAL1,ZEB2,CNIH3,RUSC2,COPS7A,FBXO25,RHOBTB1,SNAP91,AK5,RABGAP1L,DLG2,DLG3,DLX1,EXOG,NR1D2,CDON,CASP8AP2,TOM1,ABCC5,ABCC9,EDNRB,SYT15,SEMA3D,TMTC1,EIF4G2,EIF5,COPS4,PLEKHA1,MRNIP,EML1,STARD3NL,EIF1,EN2,EPHA5,EPHB1,STX2,EPS8,IGSF6,RRAGB,EYA1,NSRP1,DLC1,TOMM40L,FKTN,KAT8,ZNF589,OLFM1,FGR,CAMSAP1,FHL1,ATP5PD,CAP2,SYNCRIP,RGPD5,NELFCD,C2orf88,PDLIM5,DACH2,NRG3,MPP6,TVP23A,OGA,GABRB3,CAB39,ARPP21,MTHFD2,C15orf41,DISC1,CPLX2,GCNT2,GFRA2,FREM1,PCDH17,HEPN1,GLI2,GLRB,CBX1,GPD2,ATF7,GPR34,PCLO,RAPGEF4,ZNF496,TMEM25,MFSD2A,AP4S1,RABL2A,PSIP1,ADAMTS6,GYG1,MAEL,HAS2,PTGDR2,DDX19B,ZNF491,HNRNPK,ZDHHC15,USP51,NEGR1,LRRC75A,SHISA6,MYLK2,ITGAV,KCNA4,KCNA6,KCNJ5,KCNK2,KCNK3,KCNMA1,KCNN3,KCNQ3,KIF2A,KIF5A,KPNA5,STXBP5,KTN1,LOC100128239,MAP4,MAT2A,MATN2,MEIS1,MEIS2,N6AMT1,MYCN,NAP1L1,NAP1L2,NCAM1,NELL2,DNHD1,NTRK3,OLR1,OXTR,P2RY1,ZDHHC22,PAX6,PCDH8,PDCD2,PDE1A,PDE4D,ENPP2,PENK,NALCN,PIK3C2A,ZFYVE21,PLCL1,PCDH18,PURG,PSAT1,RETREG2,FA2H,NXPH1,PPM1B,CCDC144B,NKAIN4,PRKAR1B,PKN2,RELN,CNNM2,BCAS3,MDGA2,WDR25,PIGG,CNTLN,UHRF1BP1,BDNF-AS,TMEM260,PTPN13,MARCH1,USP47,SUSD4,NWD1,ENOX1,BSDC1,MSANTD2,RDX,DPF2,RFX2,RFX4,RGR,MRPS18A,SLC25A36,CCDC25,PCMTD2,MRAP2,MAP6D1,ABCA11P,KCNIP2,CLIP1,RYR3,ZNF331,FOXRED2,SATB1,ATXN2,HOGA1,FAM19A1,ELMOD1,SFPQ,SCAF8,NLGN4Y,SGK1,KIF16B,PAAF1,FAM81A,EPN2,LRRC55,RAB3GAP1,TMEM132D,CPEB4,CDK5RAP2,SMARCE1,RCOR3,SNAP25,FAM126B,MYO16,KDM4B,FAM219A,PDZD2,SOX2,MYCBP2,KDM4C,BEX1,KIF1B,IQSEC2,ZBTB43,C11orf87,TAB2,CLSTN2,EPB41L3,ZC4H2,NKAIN2,ZSCAN29,SEPT8,TTBK2,GSE1,ACSBG1,NECAB1,SYNE2,ANKRD28,C12orf76,MTCL1,CAMTA1,EXOC7,TBCEL,TBL1X,EHBP1,TCF4,TCF7,ZEB1,TRIM2,PSD3,PCDHB3,NSD1,AKNA,GPRIN3,FAM200B,DICER1-AS1,AP4E1,TGFBR3,GALNT17,GZF1,HEY1,ASXL3,NR2E1,CSMD1,TPD52,TPM1,DOK6,ZNF384,RGMB,SYNPO2,TRPC3,KCNE5,TTTY15,TMEFF2,HIRA,BCL2L13,CCDC136,MEAF6,WIPF1,LAT2,KLC2,RICTOR,SLC13A3,KCNT2,LYPD6,CELF4,TMEM237,POLR3H,FSTL5,CA10,MAP3K12,EMSY,PRDM2,EVI5,RNF103,NAV3,MPPE1,WNK3,SMIM8,FAM219B,ADAMTSL3,ZNF248,SSPN,KLHDC1,PIANP,IFT88,CBLN2,CPNE4" MicroRNA hsa-miR-605:mirSVR_lowEffct hsa-miR-605:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.79E-156 1.57E-152 9.32E-155 8.59E-154 432 1945 "RALGAPA1,TTYH1,ACADM,ADAR,GALNT16,TMCC3,ERMN,ADORA3,ADRA1B,DPY19L2P4,NLGN4X,MTUS1,CASKIN1,AGT,HACE1,NME5,HFM1,TAOK1,LRRC7,ALAD,SPOP,LCORL,PHF12,PPFIA1,APBB2,EPB41L5,VAT1L,AMER3,TNRC6C,API5,USP37,SHTN1,LGR5,AQP4,MIER1,PDXK,TMEM263,ARHGAP5,CDK13,ASPH,DACT3,CCAR2,ALDH4A1,ATP1A1,ATP1B3,ATP2B2,NOL4,DPY19L3,MYOM1,AZGP1,ADGRB3,MPDZ,BCL2L2,BID,KSR1,BSN,CA8,CACNA1A,CACNA1E,CACNB4,TRIM41,VSTM2A,ZNF501,CLDN10,USP6,CD38,ARHGEF2,SEPT7,CDO1,DLGAP1,CFL2,MS4A7,B4GALT6,EPS15L1,TJP2,NIPBL,PCYT1B,AKAP6,BTF3L4,AKAP5,SLC4A8,TBPL1,ACBD5,ZFP28,IGDCC3,MFSD4A,SH2B1,AATK,LRIG1,ATRNL1,IPCEF1,SIPA1L1,VCAN,PDE4DIP,CST3,FAM169A,SLITRK5,PLCXD3,CTNND1,ST18,DCAF4,RUBCN,FAM131B,ECE2,CCDC144A,BOC,LIN54,KIAA0586,MAML1,DGKB,DAPK1,TOMM20,SCRN1,SIRPA,PITPNC1,YTHDC1,MFAP3L,CEP170,TMEM130,ALKBH8,POM121,PLPPR4,SNAP91,SPOCK3,NTM,SGSM2,RABGAP1L,TMCC2,WDR20,CHRDL1,EXOG,USP3,DYNC1I1,DPYSL2,SLC25A18,DSCAM,ABCC5,DNM1L,E2F6,AASDH,HIPK3,SEMA3D,KLHL5,TMTC1,FSD1L,OPTN,FAM13A,KMT5B,EGR3,RASA4,ELN,EPB41,ETV1,EYA1,NSRP1,FAM198B,ACSL4,PPP1R1B,ZNF589,FGFR1,POLK,HPCAL4,IP6K2,SYNCRIP,RGPD5,FOXO3,FLT1,C2orf88,TACC2,FAM49B,ATP2C1,ERGIC3,SARAF,ZMAT1,HBS1L,AHCYL1,B4GALNT1,ZNF274,C15orf41,INPP5K,LRRC37A6P,GHR,PPARGC1A,DHRS4,GLYR1,RAB30,GLRB,ZNF638,GNAL,FERMT2,ADGRA3,PRUNE2,CCDC184,GRID1,GRM7,AP4S1,RNFT2,ATOH8,HAS2,HLF,GABARAPL2,SOWAHA,LRRC25,ZIC5,LRRCC1,PLD5,IGSF1,SCIN,LIX1,IL6ST,RIPPLY2,INPP5B,LRRTM3,ITGAV,JAK1,OLFM3,GPR62,KCNK1,KIF5A,LAMP2,LIG4,MATN2,LDLRAD3,SCAMP5,PPM1L,MN1,MOBP,MOG,ERICH3,JAKMIP3,MTTP,MTR,MYBPC1,MYO7A,MYO9A,NEXMIF,ZNF862,NAP1L1,NAP1L2,ZC3H12B,NDUFA5,RCOR2,SLCO1C1,NFIA,HCN1,NUMA1,ZDHHC22,PCDH9,PDE4A,PFKFB2,SERPINI1,NALCN,PIK3C2A,PIK3R1,PLTP,PDZRN4,ING3,SPATA6,EPB41L4B,SLC36A4,POU3F2,MINDY2,PPM1B,CRLS1,PTPA,PPP3CB,KANSL1,RANBP3L,PRKAB2,PRKCG,EPDR1,SAMD9,SLC22A23,MDGA2,WDR25,CNTLN,UHRF1BP1,MTMR10,OCIAD1,PTPRG,PTPRO,ZSCAN2,TUG1,RAB3IL1,SLC25A48,RAD52,FAM66C,ATG16L1,OXR1,ARID4A,BEND5,RBBP8,MSANTD2,RDX,ZYG11B,ZMAT4,RFX3,RFX5,SEC61A2,ZFHX4,ROBO2,BAALC,SGSM1,TCP11L1,RPS6KA2,MAP6D1,LGR4,SYNDIG1,ST6GALNAC6,ATAT1,RXRG,ZNF331,TRAPPC13,SAFB,SCN2B,SCN3A,FAM19A1,SCP2,GALNT10,FOXRED1,MRAS,RASA3,NLGN4Y,ITSN1,SH3GL3,FERMT1,DOCK10,NTNG1,CHD9,FHOD3,NLGN1,PAAF1,ABLIM3,SLA,SLC1A6,SLC2A5,PPP4R3A,WDR47,SLC6A1,PKNOX2,SLC9A5,TRIM67,NAPB,ELMO2,TET1,GKAP1,LIMCH1,RIMS1,FAIM2,LMBRD1,TMCC1,FAM126B,UNC80,TRERF1,SOX5,BDP1,FNBP1,SP4,RBM26,SPART,LMO3,ITPRID2,SSTR2,NKAIN2,LRRC4,SS18,RGL1,GSE1,ZC3H4,VAMP1,ARHGEF9,SYN2,SYPL1,TACC1,ROBO3,CAMTA1,AGTPBP1,TBCEL,TBL1X,MGRN1,ATMIN,EHBP1,TCF4,SATB2,ZEB1,RPGRIP1L,PCDHB9,SLC19A3,OBSL1,ARHGEF12,CCDC173,CRB1,ZNF106,HHIP,GZF1,TJP1,TK2,FAM124A,ZNF384,STXBP4,PPIL6,FNDC5,TTTY15,RFTN2,CADM1,RPL7L1,UBE2H,VAV2,SLC13A3,ZIC2,ZNF28,ZNF70,LYPD6,TMEM237,FSTL5,LAMP5,SLC38A1,ADAMTS9,FAM47E,SLC17A6,PARP11,EPM2A,RTN4,UBE3B,FBXO36,NUP214,VANGL2,FRMD6,CBLN2,SOCS4,LAS1L,JPH3" MicroRNA hsa-miR-216a:mirSVR_lowEffct hsa-miR-216a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.05E-156 1.71E-152 1.01E-154 9.33E-154 430 1928 "CPNE2,NBAT1,CSMD2,GPRIN1,ADAR,CCDC85A,ADD1,ADD2,BRAP,ADORA2A,ADRB2,NLGN4X,SLC24A4,AP2A2,WDR35,CC2D2A,SPARCL1,SMIM17,SPOP,ALCAM,GOLGA7B,TRMT9B,AMPH,ZFAT,LCORL,USP28,PHF12,PPFIA1,PKP4,APAF1,KCNAB2,ALS2,API5,USP37,APP,PPP4R4,PDXK,TMEM263,CAPRIN2,BRINP2,ASTN1,CHID1,SLC4A4,N4BP2L1,DPY19L3,LINC00847,SEC11C,BCHE,NRP2,KSR1,BMP7,BMPR1B,SYNJ1,NAE1,MTMR3,JAZF1,CA8,CA12,CACNB4,CALB1,CALM1,KALRN,PTBP2,CAMK2G,TRIM41,MAP7,CBS,METTL6,MTMR7,INA,CD38,SEPT7,CDH2,DCLK1,L3MBTL4,LOC730101,CLGN,RCBTB2,SRSF11,CHM,MS4A7,KMT2C,IGFBP7-AS1,PLAA,NMT2,TMEM59L,QKI,TMEM184B,MAP4K4,IQCK,ARMC8,AKAP6,COL4A5,SLC4A8,ABI3BP,ACBD5,SLC35F1,AKAP12,CS,MROH8,SNCAIP,RGS6,LRIG1,OSBPL3,ATRNL1,PLXNA4,DZIP3,APPL1,UBXN2A,PHF14,CTH,CFAP61,NRSN1,NOS1AP,DOCK4,ZNF337,KCTD8,DGKG,TMEM170A,DAPK1,SCRN1,ARMCX4,ZEB2,HP1BP3,CEP170,KLHL3,DDX46,GUCD1,KBTBD11,DLG2,DNAH9,DMTF1,SLC25A18,DYRK1A,ABCC5,DNM1L,E2F5,KLHL5,TMTC1,SIDT2,OPTN,RBM12,YAF2,ELAVL4,TMEM35A,EML1,COQ7,DENND4A,CDHR1,ETV1,VPS26C,DNAJC27,TLR7,SIRPB1,F5,WAC,RACK1,CHST15,TOMM40L,FCGRT,STRADA,FER,MED12L,FGF12,POLK,SUCO,PSD2,NOP56,EFCAB2,NBEA,HVCN1,CAMKK2,DACH2,PNMA2,OGA,MEGF11,CHL1,GABRB3,ZMYND11,C15orf41,TUBGCP4,ARFIP1,GFRA1,PCDH17,GGT7,TOX3,PCDH11X,OS9,LUZP2,RAB40B,GPR37,PCLO,CNTRL,GRIA1,DIDO1,RFFL,ADAMTS13,ATE1,GRM5,TMEM25,LINC01551,SOX21,LINGO1,PSIP1,ADAMTS6,MAN1B1,HLF,HMGB1,FAM95B1,ZIC5,TUBB2B,METTL21A,KCNC2,KCND1,GATD1,KIF5C,A1BG-AS1,STXBP5,INSYN2,SYTL4,SMAD1,MAN2A2,MATN3,MBP,MID1,PPM1L,AFDN,XRRA1,MMP16,BLOC1S2,MSR1,NRBP2,ZNF92,CTNNA3,RSPO2,HS6ST3,MYO6,BEX5,NAP1L2,SFR1,NFIA,NFE2L2,NTRK2,TBC1D25,IGSF11,OXTR,CNTN3,PAX6,PCSK2,PDE3B,PDGFRA,ABCB1,PIK3R1,CCSER2,NLE1,PCDH18,MTRF1L,PLXNB3,ANKRD16,RC3H2,LRP12,SCHIP1,SPATA6,RETREG2,SH3KBP1,TATDN3,CRLS1,PRKAR1B,MAPK9,RELN,SAMD9,BCAS3,MDGA2,CNTLN,ANKHD1,TMEM260,FAM120C,ZSCAN2,STRC,RAB5B,FAM184A,ZCWPW1,RBBP6,MSANTD2,ZDHHC4,ARHGEF10L,MRPS18A,LGI2,TMLHE,CARF,CYB561D1,ELP2,RPE65,ATP8B4,ACER3,TCP11L1,ATAT1,NCBP3,CCDC112,DGLUCY,ATXN7,TNFRSF19,SOX6,SELL,GALNT10,ASRGL1,SCAF8,FAM102A,PPP1R9A,FERMT1,CPEB3,SHMT2,HKDC1,MAGI3,FNDC3A,NLGN1,CTXN2,ST8SIA1,ABLIM3,SLA,PPP4R3A,RUFY2,FAM214B,SLC8A2,RAB3GAP1,CCDC88A,NAPB,SPHKAP,ZFP1,SMARCA4,SMARCD3,SMARCE1,CMTR2,SNRPN,TMCC1,KDM4B,SOX1,SOX5,BDP1,ERC1,ZNF423,ARHGAP26,KIF1B,ITPRID2,STOX1,LARP4,NXT2,MAPK8IP3,CEP68,STXBP1,NSFL1C,SYNE2,PLCB1,ANKRD28,TACC1,TACR1,MTCL1,TAL1,WWC1,AGTPBP1,TBCEL,IQCE,NEU4,KIAA0930,AZIN2,DOCK9,RALYL,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,C18orf54,HHIP,SLC44A1,TLL2,ERCC6L2,TMOD1,TNR,PIK3R5,RBFOX2,TPM3,SYNPO2,TRO,STXBP4,TRPC1,ZMYND8,ANO5,CLHC1,HIRA,RPL7L1,UGT8,OSBP2,FLRT2,VAV2,RBFOX3,WIPF1,RICTOR,GUSBP1,XPO1,ZIC1,ZNF711,ZNF708,ZNF19,GPR158-AS1,CRB2,TMEM237,ZFAND5,PRDM2,STMN4,STOX2,PRDM10,HPS4,CIAPIN1,NAV3,KCNAB1,CAB39L,FAM47E,PCBP4,GOPC,DOCK8,ST7,KAT6A,CASC15,ZNF248,VANGL2,TTC7A,NETO2" MicroRNA hsa-miR-376a*:mirSVR_lowEffct hsa-miR-376a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.95E-156 3.90E-152 2.30E-154 2.11E-153 409 1752 "RALGAPA1,SDE2,CLK4,CSMD2,GALNT16,ADCY6,BRAP,GRAMD1B,BEND6,DPY19L2P4,ZNF608,CASKIN1,PCDH19,RTL9,OSBPL1A,KIAA1324,WDR35,HFM1,LRRC7,ALAD,ARHGAP20,PCDH10,FAM135A,PITPNM2,ZFAT,OGT,ANK1,ANK3,C6orf89,PHF12,PARG,APBB1,EPB41L5,ALS2,PHYHD1,LRRC4C,API5,TMEFF1,ZFYVE28,ASCL1,DACT3,ATP1A2,RNF182,DPY19L3,DOCK11,BACH1,ADGRB1,SEC11C,BCL2L2,BCL7A,BLM,SYNJ2,C5,IL33,BTRC,CACNA1A,CACNA1D,CALM1,CAMK2A,CAMK2G,CANX,ISPD,CBLN1,RGN,MTMR7,SLC16A4,SEPT7,REPS2,CDH18,L3MBTL4,LOC730101,CDO1,SRSF11,CHN2,NDST3,CLTA,NGEF,C4orf33,QKI,NIPBL,CNN3,CNR1,COX4I1,CNRIP1,FAM171B,CREB5,GDA,MROH8,FEZ2,ARHGEF10,MICAL2,VCAN,VAC14-AS1,FAM169A,APPL1,UBXN2A,PUM1,RUBCN,USP6NL,FAM131B,HDAC9,ZFYVE16,MAML1,IST1,DGKB,DAPK1,PABPC5,GIT2,PITPNC1,DNAJC6,JAKMIP2,B3GAT3,TIAM2,FBXL5,COPS7A,MAGI2,ALKBH8,POM121,SMG7,SPOCK3,RABGAP1L,DLX1,DMD,CPEB2,DRP2,PDCD6IP,ARRDC4,ECM2,ABCC9,AASDH,USH1C,EDN1,TMTC1,RBM12,FAM13A,MRO,MBNL2,KMT5B,IRAK4,PLEKHA1,RGS17,LRRC17,GPHN,CEP85L,ETV1,EXTL2,ADGRV1,NRN1,FAM198B,EFEMP1,RACK1,TESK2,SEC24B,MED12L,FOXO3,PSD2,NOP56,NBEA,HVCN1,APOPT1,PDLIM5,NPTN,ERGIC3,KHDRBS3,DACH2,NSG1,ZMAT1,STAG2,GALNT15,GABRG2,GAD2,NKX6-2,ZNF234,IP6K3,DISC1,KIAA1841,MYOZ2,ALDH1L1,TUBGCP4,BRD8,TNRC6A,MSL3,PCDH11X,MAP7D2,RAB40B,FUT10,LPAR4,CNTRL,RAPGEF4,GRIA4,NR3C1,FAM107A,ATG4C,SCRG1,HMGCR,HNF4G,ZDHHC15,SMAP1,HTR2A,C5orf24,IL6ST,LRRTM3,JAK2,KCNA4,KCNJ9,KCNJ16,KLRC3,STXBP5,SYTL4,MAP4,MAT2A,MATN3,MBNL1,LRP1B,MEF2C,KITLG,MID1,BLOC1S2,MT1M,NRBP2,MYO6,MYO7A,NCAM1,ZC3H12B,NEK1,NELL2,NF1,NFE2L2,HCN1,OLR1,OMG,OXTR,P2RY1,CNTN3,PC,PCDH9,PDE2A,PDE3B,PDGFRA,BEST3,PFKFB3,ANLN,PIK3R1,XRN1,GPSM2,NLE1,PLIN1,HMGCLL1,PLTP,MTRF1L,PURG,TRHDE,SEPT4,DRAM2,PPM1B,PPP2R5C,PPP2R5E,PPP3CC,PRKACB,PKN2,MAPK9,MASP1,SAMD9,SIDT1,PTAFR,NCR3LG1,STK32A,PTPRB,PTPRG,FAM120C,RIPOR1,ZNF615,PID1,ACSS3,IQSEC3,FEZF2,SLC6A15,ZMAT4,RET,ERI2,GTDC1,RGS3,TTLL7,SEC61A2,SLC25A36,ZNF532,KLHDC8A,ALG9,ROBO2,MRAP2,EPHA10,TCP11L1,LRRK2,LGR4,RXRA,TRAPPC13,TMEM156,FAM192A,AP1AR,SEMA6D,SCP2,ELMOD1,SOX6,GALNT10,TRA2B,HSPA4L,SCG5,PPM1E,ST6GAL1,WDR37,PPP4R3A,SMTN,SLC6A1,RAB3GAP1,CCDC88A,SLC14A1,SLCO1A2,ZFP1,SMARCA4,OGDHL,LIMCH1,CMTR2,FAIM2,SNRPN,FAM126B,DOP1A,ZCCHC24,BDP1,ENKUR,UHRF1BP1L,PEG10,KIF1B,CDK19,NPAS3,LMO3,C11orf87,ITPRID2,SSTR1,ERBIN,SEPT3,STXBP1,JMJD6,KAZN,UNC5D,WWC1,FBXW11,EHBP1,TCF4,DMXL2,SATB2,TRIM2,HIF3A,CCDC173,FAM200B,CRB1,C18orf54,HHIP,ARL10,TJP1,ACTR6,DDHD1,ERCC6L2,FAM124A,TNS1,TP53BP1,RBFOX2,TPD52L2,C9orf85,PRMT8,ANKRD20A2,ANO5,SSBP2,HEPACAM,ZNF610,CADM1,UBE2H,FLRT2,PLEKHH2,P2RY12,CLDND1,GUSBP1,XRCC4,ZIC1,ZIC2,ZNF17,MICU3,TRIM9,ZNF70,ZNF142,ZBTB16,FSTL5,MEIS3,CADM2,PRTFDC1,DNALI1,SLC38A1,CSDE1,PRDM10,LMAN2L,PCDH15,NAV2,KCNAB1,PARP11,FAM13C,DOCK8,PAK5,JMJD1C,ZNF248,NHSL1" MicroRNA hsa-miR-593:mirSVR_lowEffct hsa-miR-593:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.57E-155 8.81E-152 5.15E-154 4.75E-153 430 1936 "DGCR6,ASIC1,CLK4,EMILIN3,NCKAP5,SYS1,CSMD2,CSMD3,ADD2,ERMN,RNF150,PTCHD1,SLC24A4,CASKIN1,AK2,C1QTNF3,USP35,ALCAM,BCAR3,GOLGA7B,FAM135A,ZFAT,ANK3,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,CACHD1,USP37,AQP6,PPP4R4,TMEFF1,ARNTL,CDK13,MARK4,CAPRIN2,ASPH,DACT3,BRINP2,NCOA1,NUMB,DDX3Y,TMEM108,ATM,EIF4G3,ZNF582,ATP6V1G2,RIPK1,ADGRB2,ADGRB3,RGS9,CFLAR,NAE1,LINC00906,CACNA1G,RAB29,BTRC,CALB2,CALM1,BRSK2,ISPD,RUNX1T1,CBR1,CBS,SHISA7,KRIT1,MTMR7,CBFA2T2,CD38,NEURL1,MYOM2,ZBED1,CDH8,CDH18,L3MBTL4,LARGE1,DIS3L,CHN2,CASC2,VAX2,DNAJB5,SRP14-AS1,CNTN1,IQCK,FAM149A,SLC4A8,MYRIP,NRG2,HS3ST5,FAM171B,C2CD2,ABCG1,SNCAIP,LRIG1,FEZ2,CSNK1E,OSBPL3,GALNT9,KIAA0408,BOC,DOCK4,HDAC9,KIAA0513,GIT2,SIRPA,DNAL1,ARMCX4,DNAJC6,ZBTB24,MFAP3L,MAGI2,GSDME,GUCD1,SNAP91,MTX3,FAM107B,DLG3,USP3,DPP6,ARRDC4,ECM2,TOM1,MAMLD1,DYRK1A,ABCC5,WDPCP,FAM135B,SEMA3D,KLHL5,SH3GLB1,PHF20L1,SORBS3,PLEKHA1,TNK2,MRNIP,RGS17,C3orf18,PAN3,EPB41L2,LRRC17,GPHN,ANKRD13B,SRRM1,SPEG,FAM198B,FABP7,TBC1D16,CORO2B,RACK1,CEP78,FKTN,PPP1R1B,GORAB,KIAA1109,OLFM1,FGFR3,TMEM164,SUCO,UBE2E3,AGAP3,FOXO3,SLC37A3,TRMO,UFM1,PDLIM5,NSG2,DACH2,B3GAT1,SARAF,AP4B1,NRG3,TVP23A,PHYHIPL,MEGF11,DKK3,HRASLS5,GABRA5,GAD1,BRPF3,ZMYND11,GALC,GALR1,ZNF274,C15orf41,DISC1,LRRC37A6P,GCK,NFU1,GHR,PPARGC1A,SPIN1,GLI2,ZNF638,KDM2B,GNAS,GNG4,GPD2,GPM6A,CCDC184,GPR19,PCLO,GRIA4,PLCD4,GRID1,GRM1,CLASRP,ZBTB49,LINC01551,ATOH8,CELF3,NXPH2,HRH3,DDX19B,AGBL5,NEGR1,SMAP1,ZNF546,SOWAHA,NKD1,SCIN,KCNH1,KCNMA1,KIF5C,A1BG-AS1,STXBP5,PAXBP1,VWA5A,HECTD2,PIK3AP1,MARK1,MBD1,MBP,MEF2C,XRRA1,COL28A1,MYT1,NF1,NKX2-2,VWA2,SLC11A2,SMIM11A,NTRK2,OPCML,OPHN1,OXTR,PAK3,PCSK5,PDCD2,PDE4B,SLC10A4,GPR85,PFKFB2,PFKFB3,CDK14,GDAP1L1,TMIE,SNX10,PLCB2,FTO,HMGCLL1,MTRF1L,PURG,LRP12,MAGEL2,PACSIN1,POU3F2,DRAM2,PPM1B,PPP2R5E,CEP41,PKIA,PRKCG,MAPK4,CNNM2,PSD,BDNF-AS,PTPRE,FAM120C,C1orf109,PEX5,TUG1,TMEM231,PLEKHB2,NWD1,RASGRF1,ARID4A,FEZF2,BSDC1,GTDC1,RGS3,RGS4,RGS12,PRIMA1,RIC8B,RNASEL,ZFHX4,CCDC82,ALG9,RAVER2,CARF,BAALC,ZNF671,MEG3,HSD11B1L,KCNIP2,RTN1,ZNF331,FAM192A,DGLUCY,SALL1,ATXN2,SCN2A,SCN8A,ELMOD1,GALNT10,MRAS,KIF21A,ITSN1,PPM1E,ASAP3,SHMT2,HKDC1,FBXO11,FNDC3A,ST3GAL3,DZIP1,SLC1A3,SLC4A3,PPP4R3A,SMTN,LRRC55,SLC8A2,RAB3GAP1,SLC12A4,ELMO2,SLC20A2,ATF7IP,OGDHL,SMARCD3,LIMCH1,RIMS1,ZNF415,SNRPN,UNC80,TNIK,SOX5,ENKUR,KDM4C,ZNF423,SPART,MAPK8IP3,ZSCAN29,PHLDB1,KANK1,SULF2,ZC3H4,VAMP1,ARHGEF9,NUDT10,ARC,ATP11A,TACC1,FAM208A,WWC1,IQCE,VWA3A,TCF4,ZFP90,TPCN2,CLASP1,WDR7,SYNE1,PMS2CL,AP4E1,GPR161,AKTIP,CDH22,SLC44A1,GALNT17,BHLHB9,HEY2,PRRT1,CSMD1,PIK3R5,RBFOX2,CDK20,TPM2,TPM3,NR2C2,SMUG1,ELP5,TRIO,RUNDC3B,TRO,TUB,RPRM,RPL7L1,UBE3A,AMOT,UBTF,UGT8,PLEKHH2,BCL2L13,VLDLR,CLIP2,LAT2,CLDND1,PCDH20,CELF4,DPYSL5,ANKS1B,TFIP11,SYNC,UPF3A,INTS3,SLC30A3,SLC38A1,RGMA,CIAPIN1,PPP1R3F,TMEM163,ITM2C,PCBP4,MVB12B,DOCK8,FAM219B,SLC4A10,CPNE4,SENP7" MicroRNA hsa-miR-3174:mirSVR_lowEffct hsa-miR-3174:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-155 1.29E-151 7.48E-154 6.89E-153 392 1616 "SERPINA3,ABCF1,AS3MT,SLC25A25,ADAR,ADCY2,PSMG3-AS1,PNMA8B,SORCS1,KIAA1211,PTCHD1,ADRB2,SLC44A5,KCTD16,RTL9,KIAA1324,UNC79,ZNF687,ANK2,MAP4K3,DGKZ,GPAM,PPFIA3,AQP4,IGDCC4,SPTBN4,PLA2G4C,ATP1A2,ATP2B2,ATP6V0A1,TTLL9,MPDZ,SEC11C,BCL7A,NRP2,CFLAR,LINC00906,BTK,C5,NIPA1,OSGIN2,CDK5R2,CA4,CA12,CACNB2,CALB1,KALRN,CAMK2G,VXN,ISPD,SPAG9,RGN,ARHGEF1,TMEM257,REPS2,CDC42,FOXN3,JAM2,KMT2C,CPNE6,RAB28,NRXN3,KIAA1549L,CLU,TPP1,CLTB,DNAJB5,SRP14-AS1,RAB26,CNTN1,ARMC8,AKAP6,SLC25A27,LETMD1,MYRIP,MFSD4A,PREPL,CRMP1,AATK,SNCAIP,CSNK1G3,NCAN,FAM169A,KIAA0040,APPL1,PNPLA8,ST18,ZSCAN23,NOS1AP,KIAA0408,BOC,SNPH,ARHGAP24,HDAC4,TOX,PHF19,TM9SF4,SCRN1,AIF1L,DCC,PITPNC1,ZEB2,ZBTB24,PLEKHM1,HP1BP3,RHOBTB1,DLG2,DMD,DYNC1I1,PDCD6IP,DTNA,ECM2,EDIL3,EDNRB,CNNM1,SEMA3D,RBM12,FAM13A,KMT5B,AASS,LPAR6,IRAK4,ELAVL4,C8orf37,EIF1,EMX2,ENO2,DMTN,ETV1,EZH1,NRN1,F5,FAM198B,ZNF461,RPS6KC1,TUBB4A,EFEMP1,FCGR1A,SLC9B2,FHL1,FOXF2,PCYOX1,SYNCRIP,FOXO3,C2orf88,JKAMP,ZBED3,ATP6V1H,ZNF605,ERGIC3,CSPG5,NSG1,MSANTD4,TVP23A,OGA,STAG2,MEGF11,GAB1,ZMYND11,B4GALNT1,JPH4,SALL3,DNER,SULT1C4,GHR,BRD8,ZNF638,GNAO1,ZNF782,PCLO,STMN2,GRIK2,TMEM25,ADAMTS6,CELF3,HAS2,DDX19B,CPT1C,RBPJ,DOCK7,IGSF1,ZNF678,INPP5B,ZNF385B,ITGAM,ITGAV,KCNA6,KCNC2,KCND2,KCNK1,KCNN2,TTYH2,LIMS1,LOC100128239,SYT9,LRP1B,MEIS2,AFDN,MOG,CPNE9,ADAM22,PTOV1,CTNNA3,RSPO2,HS6ST3,LYRM9,MYH6,NCAM1,ZC3H12B,NEFM,NFYA,NHLH1,NINJ2,NOVA1,NPTX2,OPCML,CLDN11,P2RX7,ZDHHC22,KCNK10,SNTG1,PAX6,PCDH9,PCSK5,PCSK2,CDK18,PDCD2,PDE4D,PDGFRA,GPR85,GDAP1L1,PIK3C2A,PIK3CD,XRN1,PKM,FAM216A,JAKMIP1,SMIM7,HMGCLL1,ZNF426,PNMA3,SCHIP1,RETREG2,EPB41L4B,SLC36A4,POU6F1,MED1,PPP2R2C,PPP3CA,PPP3CB,CEP41,PRKAR1B,CNNM2,SAMD9,BCAS3,CYBC1,LRRC49,SNRK,MDGA2,UHRF1BP1,ELOVL2,TMEM260,PTPN13,PTPRD,EML5,FAM120C,NKAIN1,PID1,FAM66C,ATG16L1,DBX2,FEZF2,TRIM68,DPF2,RET,REV3L,ERI2,RFX2,MRPS18A,RIC8B,ROBO2,CCDC25,PCMTD2,NEK11,ATP8B4,GLDN,SGSM1,ADAL,ACER3,TCP11L1,ABCA11P,RYR3,SALL1,SEMA6D,SCN2B,TNFRSF19,SEC14L1,MRAS,ITSN1,ASAP3,MYO18A,FNDC3A,R3HDM2,WDR37,SMTN,LRRC55,RAB3GAP1,ARHGEF40,SLC12A2,ELMO2,SMARCE1,INAVA,SNAP25,SNCA,BDP1,DOK5,SPP1,ERC1,LMO3,C11orf87,ITPRID2,ZC4H2,KLHL7,SYNE2,VPS13A,ADAMTS17,SYN2,COBL,TACC1,TACR1,MTCL1,CAMTA1,TAL1,PDLIM2,ADGRL3,TBL1X,TMEM136,VWA3A,TCEA1,DMXL2,TRIM2,DOCK9,PCDHB6,ARHGAP9,PCDHA5,AHCYL2,HIF3A,DICER1,DICER1-AS1,C18orf54,ITGB3BP,MTMR14,TJP1,NR2E1,KCTD2,RBFOX2,TPM3,WBP2,ZNF346,PDSS1,AMACR,STXBP4,TMEFF2,SLAIN1,BCL2L13,VAV2,VIPR2,RICTOR,SLC13A3,XPO1,ZBTB14,MICU3,ZNF28,ZBTB38,REEP1,TMEM237,EML6,SPIRE1,MEIS3,SLC30A4,NT5M,ADAMTS9,GAL3ST3,WIPF2,FZD3,FBXO36,ZNF248,PIANP,CBLN2,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-548c-3p:PITA hsa-miR-548c-3p:PITA_TOP PITA 2.31E-155 1.30E-151 7.50E-154 6.91E-153 338 1196 "SDE2,ACLY,CLK4,ARID1A,TMEM132B,ADD3,USP31,PWWP2A,PCDH19,HACE1,TAOK1,SPOP,FAM135A,PDZD4,PITPNM2,OGT,ANK1,ANK3,PKP4,DGKZ,GPAM,USP37,CDC14B,TMEFF1,ARHGAP5,ZBTB10,CHRD,NCOA1,ASTN1,ATP1A1,SLC4A4,ATP2B1,ATP2B2,JAZF1,LDLRAD4,THSD7A,CALM1,PTBP2,MAP7,RUNX1T1,LDB2,CDC42,NUMBL,SOCS6,CLTC,QKI,CNTN1,ARMC8,AKAP6,AHCTF1,IGDCC3,CLOCK,CREB5,CRMP1,TENM4,CHD5,ERC2,APPL1,PLCXD3,CTH,CTNND1,CTNND2,USP6NL,KIAA0408,FGFR1OP2,FRMPD4,HDAC4,MATR3,DGKB,CTIF,DBT,ZEB2,CNIH3,HP1BP3,DDX46,POM121,SGSM2,G3BP2,MTX3,DLG2,DLX1,CPEB2,CASP8AP2,DSCAM,DYRK1A,E2F5,EBF1,SNX29,HIPK3,RBM12,SH3GLB1,EFNB3,APH1A,MBNL2,KMT5B,EGR3,TMEM132E,TENM1,ELAVL2,PLEKHA1,CALCRL,PAN3,DCTN4,EMX2,EN2,EPB41,EPB41L1,EPB41L2,RCAN2,SRRM1,ERBB4,EYA1,ARMCX1,TAOK3,DLC1,ATP8A1,TESK2,FGF11,AFF2,SORBS1,FAM49B,ST6GALNAC3,STAU2,FUT9,SARAF,OGA,STAG2,MEGF11,CHL1,CAB39,AHCYL1,BRPF3,SALL3,IQGAP2,C15orf41,GHR,PPARGC1A,TCERG1,TNRC6A,PCDH11X,ZNF638,INSM2,GPD2,GPM6A,TDRKH,STON1,GRIA2,PRDM5,GRM7,FAM19A2,LINGO1,MAP4K5,CELF3,C1orf94,FRMD5,KLF12,BACH2,MIER3,HMGCR,HNF4G,HNRNPK,NEGR1,IGF1,LRRTM3,LRRTM1,KCNA1,KCNC2,KCND2,KCNJ3,KCNMA1,INSYN2,ARHGAP12,MAP2,MAT2A,MATN2,MBNL1,MEIS1,AFDN,MTTP,MYCN,NEXMIF,NAP1L3,NEK1,NFIA,NFIX,NKX2-2,PCSK1,PCSK2,PRTG,PDE4D,PFKFB2,OLA1,NLGN3,PIK3C2A,PIK3R1,SMOX,LRP12,SH3KBP1,KANSL1,PRKAB2,MAPK8,ELOVL2,PTN,PTPRD,FAM120C,PTPRZ1,PEX5,TMEM255A,ARID4A,RBBP6,RBBP8,KHDRBS2,ZMAT4,RET,REV3L,FIGN,RFX3,PBRM1,ZFHX4,CCDC82,SETD5,ALG9,CARF,ROBO1,PCMTD2,RPE,TMEM100,SPIN3,RPS6KA2,CLIP1,RXRA,NCBP3,SATB1,ATXN1,ATXN7,SCN2A,SCN3A,FNIP1,TNFRSF19,SEC14L1,SOX6,MRAS,TRA2B,PPP1R9A,SH3GL2,CPEB3,NTNG1,SHC4,MAGI3,CHD9,FBXO11,SLITRK3,NLGN1,PPP4R3A,WDR47,PKNOX2,SLC12A2,CPEB4,SMARCE1,RCOR3,RIMS1,SNAP25,TMCC1,SOX5,ZCCHC24,SOX11,SP4,HECW1,KDM4C,TEX2,ZNF423,ARHGAP26,SPART,LMO3,POGZ,ITPRID2,SSTR1,EPB41L3,LARP4,NKAIN2,LRRC4,SS18,ERBIN,ELOVL4,SEPT8,CEP68,TTBK2,GSE1,FAM168A,SYNE2,C3orf70,TAC3,ANKRD12,CAMSAP2,ADGRL3,WWC1,TCEA1,EHBP1,TCF4,SATB2,RPGRIP1L,TCF12,WASHC4,CLASP1,PSD3,PUM2,DICER1,ZFPM2,SLC44A1,NACC2,TJP1,DDHD1,ZFP91,ERCC6L2,R3HDM1,KAT6B,TRPC1,TRPS1,LRTM2,EIF4ENIF1,UBE2H,UBE3A,GORASP1,PITPNB,FLRT2,ZBTB14,ZIC2,ZNF711,TMEM237,SMARCAD1,CSDE1,WNK3,PDSS2,RGS7BP,TIGD6,VANGL2,SOCS4,CPNE4" MicroRNA hsa-miR-190:mirSVR_lowEffct hsa-miR-190:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.30E-155 1.85E-151 1.06E-153 9.80E-153 401 1692 "ACADM,CLK4,NBAT1,ACTN1,CSMD3,NDRG3,ADCY2,KLRC4,CCDC85A,PLEKHH1,PWWP2A,GPR158,HECW2,RTL9,HACE1,KIAA1324,WDR35,SPARCL1,PCDH10,BBOX1,ANK3,SEMA7A,MAP4K3,ANXA7,ALS2,APP,LGR5,MARCH3,ASPA,ASPH,TMEM108,ZNF582,NOL4,DPY19L3,BBS2,BCHE,MIR9-3HG,DCAF5,KSR1,FUBP1,C5,RAB29,LDLRAD4,CACNB4,KALRN,CAST,ISPD,CCNH,RGN,MTMR7,P2RX6,LRBA,DCLK1,LGI1,NUMBL,SRSF11,CHGA,CHGB,SOCS6,CHN1,CHRM1,B4GALT6,RAB33A,MAP4K4,NIPBL,CNTN1,AKAP7,IQCK,COL4A5,BAG4,CREB5,SNCAIP,RGS6,CNTNAP2,FAM169A,SDC3,UBXN2A,CTH,PUM1,ST18,MYADM,KATNAL2,GAPVD1,SNPH,ZNF337,RASSF2,LONRF1,MATR3,KCTD8,DGKB,DAPK1,ARMCX4,ARMCX2,ELMSAN1,JAKMIP2,C8orf34,HEPH,HP1BP3,KIAA0319,BLOC1S6,PLPPR4,SACS,NTM,MTX3,KBTBD11,NR1D2,DNM2,DOCK2,GNE,DUSP9,DNM1L,ABCC9,GOLT1B,FAM135B,SYT15,KLHL5,MBNL2,KMT5B,EGR3,TENM1,PCOLCE2,STARD3NL,C8orf37,EIF1,VPS13B,EPB41,LRRC17,EPHA5,KCNMB2,RABEPK,EPS8,DENND4A,ADGRV1,EYA1,CACNG2,TUBA1B,ATP8A1,GTF2IRD2,FGF13,SCARA3,IP6K2,RGPD5,FOXO3,SLC37A3,NOP56,SMC2,PDLIM5,STAMBP,ERGIC3,NSG1,MPP6,MEGF11,GABRA2,HRASLS5,GABRB1,GABRB3,HBS1L,ERAP1,ZNF559,DISC1,LRRC37A6P,MYOZ2,MMADHC,TCERG1,COPS8,HPGDS,FUT10,LILRA1,GPR19,GPR22,CECR2,STMN2,GRIA1,GRIN1,NR3C1,RNF165,GUCY1A1,MAEL,RASSF8,BACH2,HLF,HMGB1,SYNPO,LRRC75A,LIX1,DIPK1A,ZNF385B,KCNC2,KCND2,KCNJ3,KCNJ10,KCNK1,KCNMA1,KIF2A,KIF5A,KIT,KLRC2,A1BG-AS1,MAN2A2,MAT2A,SYT9,TM6SF1,MEF2C,MGAT3,KITLG,PPM1L,MOBP,CPNE9,SAMD5,JAKMIP3,NRBP2,CTNNA3,HS6ST3,LAYN,MYO5A,NAP1L2,NCAM1,SLCO1C1,NFIA,NHLH1,CNOT4,SLC11A2,NTRK2,SETD4,GPR88,OLR1,OMG,LOC100128398,DPY19L2P2,PCSK1,PDE4D,PIRT,PDGFRA,ENPP2,ZDHHC8,SSH1,PIK3CD,A2ML1,SNX10,RETREG1,XRN1,MTRF1L,PURG,PMP22,LRP12,EXOSC10,SDK2,NXPH1,POU3F2,KANSL1,PRKCB,MAPK4,MDGA2,CNTLN,PLPPR1,UHRF1BP1,MTMR10,PTPRB,PTPRE,PTX3,PEX5,ZSCAN2,TUG1,CEP97,PLEKHB2,ZCWPW1,RASGRF2,FEZF2,RBBP6,HKR1,SLC6A15,DPF2,RGS7,RGS12,TTLL7,CCDC82,ROBO1,ROBO2,SGSM1,PRR5L,LRRK2,AP1AR,SEMA6D,CSRNP3,SCN2B,SCP2,SLC30A10,MRAS,SCAF8,SGK1,CPEB3,DOCK10,NTNG1,MAGI3,CHD9,ST6GAL1,SLITRK3,ST3GAL3,SEC31A,SLC1A3,FAM81A,SLC6A1,SLC8A1,SLC8A3,SHANK2,NAPB,SLCO1A2,SPHKAP,SLC22A4,SLIT1,CPEB4,MAST1,SORCS3,SMARCE1,ANKRD36,FAM126B,SOX5,BDP1,ZHX3,UHRF1BP1L,KIF1B,C11orf87,CLASP2,ITPRID2,STOX1,SAMSN1,SSTR1,MAPK8IP3,ELOVL4,DIP2A,AJAP1,PRRC2C,VPS13A,NUDT10,SYPL1,SYT1,COBL,TACR1,PJA1,FAM208A,ADGRL3,KIAA1107,TBL1X,ATMIN,TCEA1,EHBP1,TCF4,DMXL2,ZEB1,TRIM2,WDR7,SYNE1,RALYL,ARHGEF12,TNS2,DICER1,ZFPM2,C18orf54,HHIP,DDHD1,KAT6B,TP53BP2,TPM1,NPL,TRIO,TRPS1,RFTN2,TUB,TMEFF2,ZNF610,FAM155A,EIF4ENIF1,BCL2L13,MEAF6,CCDC14,VSNL1,SLC13A3,XPO1,XRCC4,SF1,PCDH20,KCNT2,GPR158-AS1,NDRG4,SMARCAD1,DHX33,CADM2,LRP8,SLC38A1,EVI5,PRDM8,SCG2,MPPE1,RTN4,JMJD1C,SLC39A12,KLHDC1,FXR1,NETO1,SOCS4,SLC4A10" MicroRNA hsa-miR-195:mirSVR_highEffct hsa-miR-195:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.63E-155 3.72E-151 2.13E-153 1.96E-152 367 1420 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,ACTN1,CSMD2,GALNT13,AXIN2,CDC7,ADRB2,DPY19L2P4,AP2A1,DISP3,LRRC7,ALAD,SRPX,CEP126,ARHGAP20,OGT,ANK2,CNTNAP1,ALS2,BCAS1,API5,PPFIA3,APP,LGR5,CDC14B,CASK,STK33,ZBTB10,CCAR2,DDX3Y,TTLL9,MPDZ,RGS9,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,BTRC,CA8,CACNA1B,KALRN,PTBP2,NGB,CAMK2G,CANX,VSTM2A,MAP7,RUNX1T1,ARHGEF1,CDC27,CDC42,CFL2,CHRNA4,PPT2,CLCN3,CLCN4,COG1,QKI,BTF3L4,SLC4A7,SLC4A8,ABI3BP,TBPL1,ACBD5,MYRIP,ZFP28,MFSD4A,PREPL,HAPLN1,CRYM,LRIG1,FEZ2,MICAL2,SOCS5,ERC2,USP6NL,ARHGAP32,KATNAL2,RIPOR2,DCAF8,PHF19,KCTD8,IST1,IP6K1,GIT2,ARMCX2,YTHDC1,JAKMIP2,PLEKHM1,MYEF2,SMG7,SPOCK3,DLG2,DNM1,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,RASGRP1,SIDT2,RBM12,PHF20L1,EGFR,MBNL2,ABI2,PLEKHA1,EN2,DENND4A,CEP85L,SPEG,CDHR1,RTN3,EYA1,NRN1,ACSL4,FGFR1,PRKAG2,SUCO,RGPD5,SGIP1,SLC37A3,PDLIM5,ARFGAP2,CSPG5,NSG1,ZNF512,PHYHIPL,GALNT15,ARPP21,DISC1,SESN1,USP19,PCDH17,GHR,SPIN1,INSM2,FERMT2,GPD2,PCLO,RAPGEF4,GRM7,RNF165,PTPN5,WIF1,RASSF8,ZHX1,FRMD3,MIER3,SHISA6,HTR2A,MSL1,RBPJ,NIM1K,SCRT2,INPP1,NME9,SLC35G1,KCNC2,KCND2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,ARHGAP12,PACRG,MAP4,MAP6,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,CD200,THYN1,MYBPC1,RTL5,NAP1L2,NDP,NOVA1,SLC11A2,NTRK3,ODF2,OMG,CNTN3,ETFRF1,PCDH9,PCMT1,PDE3B,BEST3,PIK3R1,JAKMIP1,PLP1,PLXNB3,PSAT1,PRRX1,SDK2,MAGEL2,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,PKN2,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,PIGG,CNTLN,PTCH1,PTHLH,STK32A,ZSCAN32,PTPRD,PEX5,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,ZDHHC14,RDX,RET,RFX4,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,ARMH4,FBXW7,SYNDIG1,ABCA11P,KCNIP1,ZNF568,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN2A,SCN3A,SCN8A,ELMOD1,SLC30A10,COPZ1,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,ST3GAL3,ANKRD6,FAM81A,RAB3GAP1,ARHGEF40,KBTBD4,SLC20A2,SLC22A4,SLN,ZFP1,RCOR3,SNAP25,MBD5,SNRPN,UNC80,SON,MYT1L,UNC5B,ZC3H13,KIF1B,TSPYL2,NPAS3,NFASC,LMO3,RGL1,ACSBG1,PRRC2C,SYNE2,VPS13A,C3orf70,SYPL1,COBL,SYT4,C12orf76,KAZN,WWC1,TBCEL,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,TGFBR3,TMEM9,DDHD1,ERCC6L2,HEY2,TMOD1,KAT6B,TP53BP2,TPM2,RUNDC3B,TRPC1,TRPC3,CADM1,AMOT,LGI4,ZNF708,TRIM9,NDRG4,REEP1,FSTL5,EML6,SLC30A4,PMEPA1,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,RNF170,SNX14" MicroRNA hsa-miR-576-3p:mirSVR_lowEffct hsa-miR-576-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.82E-155 4.39E-151 2.50E-153 2.30E-152 434 1979 "ABAT,KCNH8,CLK4,SYS1,ACTN2,ADAR,GALNT16,ADCY2,PSMG3-AS1,CCDC85A,RNF157,SORCS1,PLEKHH1,GRAMD1B,ADORA2A,UNC5A,KIDINS220,BEND6,HECW2,HACE1,CC2D2A,C1QTNF3,LRRC7,BCAR3,PCDH10,GPRASP2,KIF6,ANK1,FGD2,C6orf89,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APBA2,MAGEE2,TNRC6C,APP,MIER1,IGDCC4,ARHGAP5,RGS20,ARRB2,ASPH,TMEM108,SLC4A4,SLC2A11,MTMR9,ADAM15,BACH1,BBS2,MPDZ,SEC11C,BID,BMPR1B,LINC00906,CASTOR3,SGCE,BSN,CA12,CALB1,PTBP2,CAST,PRC1,USP6,CBFA2T2,C1orf52,DGKI,ARHGEF2,CDH8,ZMYM4,DLGAP1,CACNA2D2,ASIC3,CHM,CHN2,CASC2,LSMEM2,EPS15L1,NRXN3,IGFBP7-AS1,CLTA,FADS2,QKI,MAP4K4,ARHGEF6,AKAP6,RCHY1,IFFO1,BAG4,IGDCC3,SLC35F1,CDC42BPB,CREM,CREB5,NCOR1,ABCG1,RGS6,MICAL2,CSNK1G3,ATRNL1,VAC14-AS1,CNTNAP2,PLXNA4,FAM169A,DZIP3,PHF14,CTNND1,ST18,ZSCAN23,USP6NL,CX3CR1,CCDC144A,KIAA0408,HDAC9,TOX,EARS2,ZNF337,DGKG,TMEM170A,ARMCX4,DNAJC6,HEPH,FBXL5,TMEM130,BLOC1S6,RHOBTB1,SMG7,SNAP91,SACS,SV2A,NTM,RABGAP1L,WDR20,FAM107B,CCDC3,CHRDL1,CDON,DNM2,SLC12A6,DPP6,PDCD6IP,DTNA,DYRK1A,ABCC9,SNX29,EDNRA,EDNRB,CNNM1,SEMA3D,SH3GLB1,EFNB3,SUGP2,ABI2,COPS4,PCOLCE2,TMEM35A,EPB41,EPB41L1,EPB41L2,EPHB1,KCNMB2,GPHN,STX2,EPS8,CDHR1,ETV1,RCSD1,KATNAL1,F8,FAM198B,ATP8A1,GTF2IRD2,BAIAP2,FHL1,POLK,SCARA3,MEX3B,HPCAL4,PSD2,NELFCD,AKAP3,SORBS1,SMC2,USP16,PDLIM5,ERGIC3,CGREF1,PNMA2,PHYHIPL,DKK3,GAB1,AHCYL1,ZNF274,INPP5K,WASF3,GATM,NEU3,MSTN,ARFIP1,MMADHC,GFRA2,GGT7,HPGDS,GLI2,MSL3,CBX1,KDM2B,LUZP2,LILRB4,LILRA1,GPR12,GRK4,RAPGEF4,STMN2,GRIA1,GRIA4,NR3C1,BTN2A1,PTPRT,BVES,AP4S1,LINGO1,GUCY1A2,RNFT2,GUCY1B1,ATOH8,GYG1,WIF1,MAEL,NXPH2,ARHGAP36,LINC01102,HMGCR,FAM95B1,LINC00667,DISP2,PLD5,LIX1,ZNF385B,ITPKB,SLC35G1,KCNC2,KCNJ5,KIF5A,KIF5C,KLRC3,INSYN2,SYTL4,NCOA7,MAP4,MATN2,CHIC1,MEF2C,KITLG,MOBP,JAKMIP3,MSRA,SCG3,MXI1,MYH7,NAP1L3,NCAM1,NCAM2,NEK1,NF1,ALDH1L2,NTRK2,NTRK3,NUCB2,OMG,OPCML,PDE3B,PDYN,GPR85,ZDHHC8,SSH1,PIK3C2A,PIK3CD,CCSER2,SNX10,GPSM2,FTO,FXYD1,HMGCLL1,PSAT1,SCHIP1,PPM1B,PPP3CB,RANBP3L,PRKACB,CEP41,PRKCB,MAPK10,HYDIN,RELN,SYTL2,MDGA2,PTHLH,TMEM260,OCIAD1,PTPRE,PTPRH,PTPRO,C1orf109,PEX5,SH3TC2,RAP1GDS1,ZNF493,RBBP6,RDX,ZYG11B,ERI2,GTDC1,UBR7,RGS3,RGS7,RGS12,PRIMA1,ARHGEF10L,SEC61A2,TMLHE,KLHDC8A,ALG9,CARF,ROBO1,ROBO2,PGBD4,GLDN,SGSM1,ACER3,ATAT1,KCNIP2,RXRG,FAM182A,MIR124-2HG,SATB1,ATXN2,LRRTM4,FAM19A1,SCN8A,LINC00461,SCP2,TNFRSF19,ASIC4,SOX6,TRIM46,ZFP30,AMBRA1,FBXO11,ST3GAL3,SLC8A1,SLC8A3,SORCS3,RIMS1,SNRPN,SON,SOX5,FNBP1,DOK5,NMNAT2,PEG10,ZC3H13,CDK19,ZBTB43,C11orf87,ITPRID2,KANK1,SULF2,SYT11,SYNE2,DNAJC9,SYN1,SYT4,MTCL1,MLST8,KIAA1107,IQCE,ANO4,ZFP90,CUX2,TCF7,TCF7L2,NSD1,FRYL,DICER1-AS1,TGFBR3,SLC44A1,TK2,ZFP91,TMPO,FAM124A,R3HDM1,TPD52,TSN,ZKSCAN5,TUBB1,UBE3A,SLAIN1,ZNF709,VIPR2,WIPF1,LAT2,PORCN,SLC13A3,ZBTB14,ZNF708,FMN2,PLPP4,LYPD6,TCEAL7,TMEM198,EML6,FTSJ1,SMARCAD1,SYNC,DHX33,EMSY,SLC38A1,STMN4,STOX2,GAL3ST3,SLC17A7,KCNAB1,FAM47E,ST7,HNRNPA3,PHTF2,SLC39A12,NETO1,SLC4A10,CPNE4,SPATA13" MicroRNA hsa-miR-376b:mirSVR_lowEffct hsa-miR-376b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.19E-155 4.60E-151 2.60E-153 2.39E-152 394 1638 "NBAT1,XKR4,GALNT13,ERMN,RNF150,NLGN4X,ZNF608,AGT,RTL9,KIAA1324,CC2D2A,PLA2G6,C1QTNF1,ALCAM,FAM135A,GPRASP2,TRMT9B,PITPNM2,ANK3,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,MAGEE2,DGKD,AMER3,USP37,ARHGAP5,DACT3,ZBTB10,NUMB,ASTN1,TMEM108,ATM,SLC4A4,ATP2B3,MTMR9,DPY19L3,CFLAR,BMPR1B,DST,SYNJ1,LINC00906,MTMR2,CACNA1E,CACNB2,KALRN,PTBP2,SPAG9,NFS1,ENTPD6,CDH2,DCLK1,ZMYM4,LRRFIP1,CDH18,LOC730101,CHN2,CHRNA4,B4GALT6,RAB33A,ZFYVE9,CLCN3,SRP14-AS1,HECTD1,TMEM155,FHL5,CNN3,ARMC8,SUMF2,RTTN,ZNF521,NRG2,PREPL,CREM,NCOR1,CLIP3,CSF2RA,ARHGEF10,MICAL2,CNTNAP2,DZIP3,CMTM5,PHF14,PNPLA8,CTH,PUM1,ST18,FAM131B,DCAF8,FRMPD4,ZNF337,PABPC5,DNAL1,JAKMIP2,CEP170,MAGI2,BLOC1S6,LYPD1,DDX46,SPOCK3,SRGAP3,ARNT2,DLG2,DLX1,GRIN3A,DMD,NR1D2,DOCK2,DRD1,ACOT8,GNE,GOLT1B,CNNM1,SEMA3D,FRY,YAF2,FAM13A,KMT5B,ABI2,AASS,EIF4G2,EIF5,PLEKHA1,RGS17,CALCRL,EN2,VPS13B,LRRC17,DENND4A,RTN3,EXTL2,F5,TUBB4A,SCML2,EFEMP1,ST3GAL6,ZSCAN30,SEC24B,FER,FGF1,FGF14,FGFR1,SUCO,UBE2E3,FOXG1,PCYOX1,FLT1,NOP56,PDLIM5,NPTN,DACH2,MSANTD4,MEGF10,GAB1,CHL1,GABRG1,GABRG2,BRPF3,IQGAP2,DISC1,ATP8A2,KIAA1841,FAXC,MSTN,PCDH17,PPARGC1A,GLI2,GLS,MSL3,INSM2,LUZP2,GNAS,GPD2,ATF7,LILRA2,GPR12,GRIA2,GRIK3,SERP2,ATE1,GRM3,AP4S1,LINGO1,MAP4K5,CELF3,MAEL,C1orf94,NEGR1,OPALIN,NKD1,RBPJ,LRRCC1,PLD5,HES5,IL6ST,INPP5B,JAK2,SLC35G1,KCNK2,KIF5C,LIMS1,MATN2,MBP,CHIC1,MEIS2,MEST,KCTD6,AFDN,ZNF680,SAMD5,BLOC1S2,MSR1,MSRA,ZNF92,MTTP,MTR,RSPO2,NEXMIF,ZC3H12B,NEUROD1,NFE2L2,NOS1,NPTX1,NTRK2,GPR137C,PAH,PAX6,PCDH8,PCSK5,ENPP2,PDYN,PFKFB3,NALCN,PIK3C2A,PIK3R1,A2ML1,ZFYVE21,XRN1,ST8SIA5,PLCL1,PLIN1,PURG,PDZRN4,STRN3,RETREG2,SLC36A4,FAT3,PPARA,PTPA,RASGEF1B,PRKCB,DIRAS2,BCAS3,ANKHD1,PTN,FAM120C,PEX5,TUG1,TMEM255A,SH3TC2,RAP1GDS1,ENOX1,OXR1,MSANTD2,REV3L,RFX3,RGS12,RIC8B,RNASEL,LGI2,ARMC5,CCDC102B,FBXW7,ZC3H14,ADAL,CNTNAP3,MEG3,HUNK,ATAT1,ZNF354C,CCDC112,DGLUCY,SATB1,LRFN5,SCP2,FNIP1,IL17RB,SFPQ,SCG5,KIF21A,PPP1R9A,SH3GL3,PPM1E,FNDC3A,R3HDM2,NLGN1,CTXN2,DZIP1,BTBD3,SLC8A3,ZNF334,SLC15A2,CPEB4,ZFP1,SMARCC2,ANKRD36,SNRPN,PALLD,FAM126B,SON,WDTC1,TRERF1,ENKUR,UHRF1BP1L,C11orf87,CLASP2,TROVE2,STOX1,MAPK8IP3,CEP68,TTBK2,ADHFE1,KANK1,SEPT3,KLHL7,FGD4,PLCB1,SYN2,SYPL1,TAC1,PDLIM2,UNC5D,WWC1,TMEM136,MGRN1,SATB2,TPCN2,RPGRIP1L,RALYL,PCDHB7,PUM2,USP32P1,ARHGAP9,SLC35G2,DICER1-AS1,ITGB3BP,TGFBR3,TLL2,ZFP91,HEY2,TMOD1,KCTD2,TP53BP1,NPL,C9orf85,STXBP4,TRPC3,TSN,TUB,ZKSCAN5,SGK3,FAM155A,UBE2H,PLEKHH2,XPO1,XRCC4,MICU3,ZNF28,ZNF32,AGMO,FMN2,GPR158-AS1,TMEM237,ZNF177,EML6,ZSCAN26,INTS3,WNK1,EMSY,CADM2,LRP8,STOX2,FAM47E,FAM13C,AMN1,DOCK8,RSPRY1,RNF170,KLHDC1,NETO1,SOCS4,SLC4A10" MicroRNA hsa-miR-520d-5p:PITA hsa-miR-520d-5p:PITA_TOP PITA 1.22E-154 6.83E-151 3.81E-153 3.51E-152 297 915 "CPNE2,CSMD3,ADD1,USP31,NLGN4X,INTS2,MTUS1,OSBPL8,UNC79,EP400,MAP4K3,FAM131A,API5,PPFIA3,MARK4,DACT3,NCOA1,CCAR2,ATP2B1,ATP2B2,DPY19L3,JAZF1,CALM1,CBLN1,C1orf52,LRBA,CDC42,CDH2,ARHGAP33,CDO1,CCPG1,CACNA2D2,FOXN3,SOCS6,CHN2,JAM2,KMT2C,NRXN3,TJP2,QKI,TMEM184B,HECTD1,CNR1,ARMC8,COL4A5,AKAP5,AHCTF1,CNRIP1,CDC42BPB,RBM39,CRHBP,CREB5,CRMP1,LRRC3B,CSNK1E,OSBPL3,CSNK1G3,CHD5,APPL1,PUM1,ST18,KIAA0408,DOCK4,KIF26A,MATR3,DBN1,DNAJC6,ZEB2,SMG7,SNAP91,DLX1,GRIN3A,DYNC1I1,CDON,CPEB2,DRD1,ARRDC4,MAMLD1,DYRK1A,GOLT1B,FAM135B,EDN3,EDNRA,ANKRD46,KLHL5,RBM12,SH3GLB1,CELSR3,MBNL2,COPS4,ELAVL2,STARD3NL,PAN3,EPB41,EPB41L2,RCAN2,SEZ6,EPHA5,SLC43A2,EFEMP1,PPP1R1B,SEC24B,SUCO,UBE2E3,SYNCRIP,AGAP3,AFF2,NBEA,TACC2,SORBS1,PDLIM5,CELF1,MPP6,OGA,GABRB3,CAB39,NKX6-2,CPLX2,GBX2,SESN1,GK,RNPS1,GLRB,STARD3,GNAO1,GPM6A,GRB10,GRIA2,GRID1,FAM19A2,IL1RAPL1,LINGO1,ADAMTS6,ZHX1,HNRNPK,NEGR1,HES5,LRRTM3,ITPKB,KCNA1,KCNQ3,KIF2A,KIF5A,INSYN2,ARHGAP12,MAPT,MBNL1,CHIC1,LRP1B,MEF2C,SCAMP5,MID1,MITF,AFDN,MXI1,MYO6,NEXMIF,NCAM1,ZC3H12B,NFIA,NFIX,SMIM11A,HCN1,IGSF11,OPA1,OPHN1,GPR137C,PCDH9,PDE2A,PFKFB3,NLGN3,PRRX1,MINDY2,PPP3CA,PPP5C,CEP41,PKN2,DIRAS2,PSD,ELOVL2,PTK2,PTN,PTPN13,PTPRD,PTPRE,PTPRO,FAM120C,PEX5,RAB5B,USP47,FAM184A,RAP1GDS1,FEZF2,BSDC1,RDX,GTDC1,FIGN,RGS7,RNF220,SETD5,LGR4,SOX8,ATXN2,SCN2A,FAM19A1,FNIP1,SOX6,MRAS,NLGN4Y,CPEB3,MAGI3,SLITRK3,NLGN1,WDR37,SLC1A2,SLC1A3,PPP4R3A,WDR47,CCDC88A,SLC12A2,CPEB4,PALLD,PDZRN3,MYO16,SON,PDZD2,MYT1L,ZCCHC24,SOX11,ZHX3,SP4,RBM26,LMO3,SRPK2,TAB2,SS18,ERBIN,SEPT8,GSE1,PRRC2C,TAL1,FBXW11,TBL1X,TCF4,TCF7L2,SZT2,ARHGEF12,PUM2,CRTC1,SIRT1,ZNF106,GZF1,TIAM1,HEY1,TJP1,CBX5,DDHD1,ZFP91,ERCC6L2,HEY2,RIMBP2,KAT6B,RBFOX2,TPM1,TPM3,TRPS1,HEPACAM,CADM1,FLRT2,MTCH1,MEAF6,ZIC1,ZNF711,LYPD6,ZBTB38,SMARCAD1,WNK1,CA10,DNALI1,LRP8,CSDE1,TMEM178A,NAV3,ITM2C,SLC17A6,RGS7BP,FAM13C,FZD3,PAK5,KAT6A,CERS6,ADAMTSL3,JMJD1C,MSRB3,NETO2,SLC4A10,FAM181A" MicroRNA hsa-miR-524-5p:PITA hsa-miR-524-5p:PITA_TOP PITA 1.22E-154 6.83E-151 3.81E-153 3.51E-152 297 915 "CPNE2,CSMD3,ADD1,USP31,NLGN4X,INTS2,MTUS1,OSBPL8,UNC79,EP400,MAP4K3,FAM131A,API5,PPFIA3,MARK4,DACT3,NCOA1,CCAR2,ATP2B1,ATP2B2,DPY19L3,JAZF1,CALM1,CBLN1,C1orf52,LRBA,CDC42,CDH2,ARHGAP33,CDO1,CCPG1,CACNA2D2,FOXN3,SOCS6,CHN2,JAM2,KMT2C,NRXN3,TJP2,QKI,TMEM184B,HECTD1,CNR1,ARMC8,COL4A5,AKAP5,AHCTF1,CNRIP1,CDC42BPB,RBM39,CRHBP,CREB5,CRMP1,LRRC3B,CSNK1E,OSBPL3,CSNK1G3,CHD5,APPL1,PUM1,ST18,KIAA0408,DOCK4,KIF26A,MATR3,DBN1,DNAJC6,ZEB2,SMG7,SNAP91,DLX1,GRIN3A,DYNC1I1,CDON,CPEB2,DRD1,ARRDC4,MAMLD1,DYRK1A,GOLT1B,FAM135B,EDN3,EDNRA,ANKRD46,KLHL5,RBM12,SH3GLB1,CELSR3,MBNL2,COPS4,ELAVL2,STARD3NL,PAN3,EPB41,EPB41L2,RCAN2,SEZ6,EPHA5,SLC43A2,EFEMP1,PPP1R1B,SEC24B,SUCO,UBE2E3,SYNCRIP,AGAP3,AFF2,NBEA,TACC2,SORBS1,PDLIM5,CELF1,MPP6,OGA,GABRB3,CAB39,NKX6-2,CPLX2,GBX2,SESN1,GK,RNPS1,GLRB,STARD3,GNAO1,GPM6A,GRB10,GRIA2,GRID1,FAM19A2,IL1RAPL1,LINGO1,ADAMTS6,ZHX1,HNRNPK,NEGR1,HES5,LRRTM3,ITPKB,KCNA1,KCNQ3,KIF2A,KIF5A,INSYN2,ARHGAP12,MAPT,MBNL1,CHIC1,LRP1B,MEF2C,SCAMP5,MID1,MITF,AFDN,MXI1,MYO6,NEXMIF,NCAM1,ZC3H12B,NFIA,NFIX,SMIM11A,HCN1,IGSF11,OPA1,OPHN1,GPR137C,PCDH9,PDE2A,PFKFB3,NLGN3,PRRX1,MINDY2,PPP3CA,PPP5C,CEP41,PKN2,DIRAS2,PSD,ELOVL2,PTK2,PTN,PTPN13,PTPRD,PTPRE,PTPRO,FAM120C,PEX5,RAB5B,USP47,FAM184A,RAP1GDS1,FEZF2,BSDC1,RDX,GTDC1,FIGN,RGS7,RNF220,SETD5,LGR4,SOX8,ATXN2,SCN2A,FAM19A1,FNIP1,SOX6,MRAS,NLGN4Y,CPEB3,MAGI3,SLITRK3,NLGN1,WDR37,SLC1A2,SLC1A3,PPP4R3A,WDR47,CCDC88A,SLC12A2,CPEB4,PALLD,PDZRN3,MYO16,SON,PDZD2,MYT1L,ZCCHC24,SOX11,ZHX3,SP4,RBM26,LMO3,SRPK2,TAB2,SS18,ERBIN,SEPT8,GSE1,PRRC2C,TAL1,FBXW11,TBL1X,TCF4,TCF7L2,SZT2,ARHGEF12,PUM2,CRTC1,SIRT1,ZNF106,GZF1,TIAM1,HEY1,TJP1,CBX5,DDHD1,ZFP91,ERCC6L2,HEY2,RIMBP2,KAT6B,RBFOX2,TPM1,TPM3,TRPS1,HEPACAM,CADM1,FLRT2,MTCH1,MEAF6,ZIC1,ZNF711,LYPD6,ZBTB38,SMARCAD1,WNK1,CA10,DNALI1,LRP8,CSDE1,TMEM178A,NAV3,ITM2C,SLC17A6,RGS7BP,FAM13C,FZD3,PAK5,KAT6A,CERS6,ADAMTSL3,JMJD1C,MSRB3,NETO2,SLC4A10,FAM181A" MicroRNA hsa-miR-96:mirSVR_lowEffct hsa-miR-96:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-154 1.00E-150 5.56E-153 5.12E-152 407 1750 "ACADM,NBAT1,SLC25A25,PWWP2A,MTA3,SLC44A5,KCTD16,AK2,ADGRF5,SEMA6A,CEP126,PCDH10,GPRASP2,AMPD2,ZFAT,OGT,CDC42BPA,ANK3,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APBB2,APC,RGS20,LINC00173,ASTN1,INSYN2B,ATP1A2,ATP1B3,ZNF582,B3GALT2,BACH1,KSR1,MTMR3,CACNA1G,NIPA1,MYRF,CDK5R2,MMD2,CACNB2,CALB1,ZNF501,CERS5,INA,SCARB1,EVI5L,L3MBTL4,SRSF11,RAB3C,LSMEM2,NRXN3,NRXN1,FBXO7,MAP4K4,SLC4A8,COX4I1,BAG4,CLOCK,ENTPD4,CREB5,CRY2,SNCAIP,MICAL2,ATRNL1,CNTNAP2,GREB1,NRSN1,RIMS2,USP6NL,CCDC144A,DOCK4,TOX,ZFYVE16,IST1,TMEM170A,SCRN1,SPOCK2,DBI,PLEKHM1,ELMO1,TIAM2,CEP170,RHOBTB1,SACS,SV2B,HS3ST4,USP3,DYNC1I1,CPEB2,SLC12A6,RCAN1,ARRDC4,DTNA,MAMLD1,AASDH,EBF1,SNX29,EDN1,EDNRB,TMTC1,APH1A,MBNL2,KMT5B,KCTD3,EIF5,ING4,RGS17,OLIG2,EPB41L2,EPS8,IGSF6,NRN1,ARMCX1,ATP8A1,RACK1,CEP78,PRMT5,FER,FGF13,FGFR1,FGR,AMOTL2,SUCO,ANKFY1,FLYWCH1,SORBS1,CAMKK2,ATP2C1,KHDRBS3,CELF1,DACH2,CGREF1,SARAF,FYB1,STAG2,HRASLS5,LRRC37A6P,SESN1,GFRA1,FREM1,PCDH17,LYVE1,GJB1,TXNL4A,CRCP,TOX3,TNRC6A,AIFM3,STARD3,KDM2B,LUZP2,RAB40B,GPD2,PRUNE2,ATF7,PRLHR,LPAR4,GPR34,CNTRL,NR3C1,GRM1,GRM2,GRM5,ZNF496,GSTM5,MFSD2A,ADAMTS6,GUCY1B1,PADI2,ARHGAP19,KLF12,HMGB1,SHISA6,ICA1,LINC00667,LRRC25,RBPJ,TJAP1,ZNF678,DIPK1A,ITGAM,SLC35G1,KCNB1,KCND2,KCNMA1,KCNN3,KIF2A,KIF5C,STXBP5,LAMP2,INSYN2,LIMS1,HECTD2,SMAD1,LYPLAL1,MBNL1,SYT9,CHIC1,MDM4,SRSF12,MIA2,MID1,CPNE9,COMMD5,MT1M,MT3,N6AMT1,MTR,NEXMIF,NAP1L3,NCAM1,NCAM2,NELL1,NEK1,NEUROD1,NPTX2,NRCAM,IGSF11,CHAMP1,OGDH,OLR1,OPHN1,LOC100128398,ZDHHC22,PAH,PCDH8,PCMT1,CDK18,PRTG,PDGFRA,GPR85,PFKFB2,PIK3R1,CCSER2,NLE1,HMGCLL1,EXOSC10,MAGEL2,ING3,TMEM235,PPP3CA,VSTM2L,PRKAB2,GRAMD1C,MASP1,CNTLN,BDNF-AS,PTHLH,PTK2,PTN,TMEM260,PTPRG,PTPRZ1,TMEM145,PPP2R3C,SLC25A48,RAD17,PLEKHB2,RALGDS,ATG16L1,ZNF493,OXR1,ARID4A,RET,ERI2,GTDC1,RFX4,PRIMA1,ARHGEF10L,RNF220,RPRD1A,CCDC82,TMLHE,ALG9,ROBO1,ROBO2,ELP2,SPIN3,SGSM1,PTGR2,ABCA11P,RYR3,AMER2,SATB1,ATXN1,LRRTM4,SCN7A,SELL,SCAF8,NTNG1,SHC4,FNDC3A,SLITRK3,CCDC92,ZNF365,FAM214B,SLC8A3,CCDC88A,SLC12A2,SLC14A1,MTERF2,ELMO2,ATF7IP,CPEB4,SORCS3,CDK5RAP2,SMARCE1,LIMCH1,KIF13A,FAIM2,SNRPN,PALLD,TMCC1,UNC80,SOX2,FNBP1,GLT8D1,PEG10,SPTB,MCF2L2,NPAS3,SPART,TROVE2,STOX1,SSPO,NXT2,SEPT8,DIP2A,SYNE2,COBL,TACC1,CAMTA1,CAMSAP2,ADGRL3,ANO4,TCF4,SIN3B,SATB2,TCF12,PCDHGB7,SYNE1,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,LRRC8A,TMPO,KCTD2,TNR,TNS1,TPM2,ZNF384,SYNPO2,PRMT8,TRPC3,CLHC1,SGK3,CADM1,PLPPR2,P2RY12,NSD2,RICTOR,XPO1,XRCC4,ZBTB14,ZIC2,ZNF23,ZNF24,FMN2,LYPD6,TCEAL7,EML6,ZNF189,PLPPR5,UPF3A,PMEPA1,PRDM2,SLC38A1,PRDM8,PRDM10,VPS35L,TMEM163,SLC17A6,MVB12B,C12orf4,RGS7BP,ST7,MARCH8,RTN4,PAK5,KAT6A,PHTF2,ZNF248,FXR1" MicroRNA hsa-miR-106a:mirSVR_highEffct hsa-miR-106a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.63E-154 1.48E-150 8.12E-153 7.48E-152 389 1602 "KCNH8,NCKAP5,FMNL2,SORCS1,SLC24A4,ABCD2,MRTFA,SEMA7A,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,APP,SHTN1,AQP4,CASK,LINC00173,STK33,CAPRIN2,ASPH,RASL11B,ASTN1,ATP1A2,SLC4A4,EIF4G3,ATP1B3,B3GALT2,NOL4,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,MAP7,USP6,P2RX6,C1orf52,TIGD7,CFL2,CASC2,MS4A7,B4GALT6,TAOK2,EPS15L1,ZFYVE9,TPP1,ABCG2,SLC25A27,AKAP5,SLC4A8,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,TOMM20,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,RABGAP1L,OLIG1,USP3,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,ANKRD46,EFNA3,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,EFCAB2,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,GABBR1,GABRA1,TRAF3IP2,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,GRM7,CIT,LINC00839,TMEM25,AP4S1,RABL2A,IRAK3,HAS2,HPS5,HTR5A,MSL1,JAK1,METTL21A,OLFM3,KCNJ10,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,SRSF12,MID1,POC1B,XRRA1,MOG,CD200,MSR1,MXI1,MYCN,MYH6,NACA,NCF2,SFR1,NELL1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PRRX1,SPATA6,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,TMEM260,PTPN13,PTPRD,PTPRO,RAB5B,CEP97,TMEM255A,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,ATXN2,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,PPP4R3A,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,SOX2,IQSEC2,ZBTB43,NPAS3,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FAM168A,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,RALYL,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,PRMT8,TTPA,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,WNK1,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,RNF103,PCDH15,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-17:mirSVR_highEffct hsa-miR-17:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.63E-154 1.48E-150 8.12E-153 7.48E-152 389 1602 "KCNH8,NCKAP5,FMNL2,SORCS1,SLC24A4,ABCD2,MRTFA,SEMA7A,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,APP,SHTN1,AQP4,CASK,LINC00173,STK33,CAPRIN2,ASPH,RASL11B,ASTN1,ATP1A2,SLC4A4,EIF4G3,ATP1B3,B3GALT2,NOL4,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,MAP7,USP6,P2RX6,C1orf52,TIGD7,CFL2,CASC2,MS4A7,B4GALT6,TAOK2,EPS15L1,ZFYVE9,TPP1,ABCG2,SLC25A27,AKAP5,SLC4A8,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,TOMM20,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,RABGAP1L,OLIG1,USP3,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,ANKRD46,EFNA3,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,EFCAB2,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,GABBR1,GABRA1,TRAF3IP2,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,GRM7,CIT,LINC00839,TMEM25,AP4S1,RABL2A,IRAK3,HAS2,HPS5,HTR5A,MSL1,JAK1,METTL21A,OLFM3,KCNJ10,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,SRSF12,MID1,POC1B,XRRA1,MOG,CD200,MSR1,MXI1,MYCN,MYH6,NACA,NCF2,SFR1,NELL1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PRRX1,SPATA6,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,TMEM260,PTPN13,PTPRD,PTPRO,RAB5B,CEP97,TMEM255A,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,ATXN2,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,PPP4R3A,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,SOX2,IQSEC2,ZBTB43,NPAS3,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FAM168A,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,RALYL,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,PRMT8,TTPA,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,WNK1,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,RNF103,PCDH15,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-1243:mirSVR_lowEffct hsa-miR-1243:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-154 2.24E-150 1.22E-152 1.13E-151 390 1612 "CLK4,SLC25A25,CSMD3,KLHL32,GALNT13,PNMA8B,SORCS1,NLGN4X,AP2A2,KCTD16,OSBPL1A,KIAA1324,SEMA6A,SPOP,PCDH10,FAM135A,ZFAT,OGT,DPP10,PPFIA1,PARG,APBB2,EPB41L5,LGR5,PDXK,IGDCC4,ARHGAP5,CDK13,ASPH,BRINP2,DDX3Y,ATM,SLC4A4,ATP2B1,ZNF583,ADGRB3,CFLAR,SYNJ2,ARHGEF7,CACNA1G,C5,NIPA1,OSGIN2,CALB1,KALRN,VXN,SYT6,MAP7,RUNX1T1,PRC1,LDB2,METTL6,CD38,REPS2,LGI1,FOXN3,CHI3L2,CASC2,B4GALT6,NDST3,C7orf61,RAB33A,PLAA,CLCN4,COG1,MYL6B,TJP2,MAP4K4,NIPBL,ARMC8,SLC4A7,SLC4A8,ZFP28,CNRIP1,HS3ST5,CPS1,CLOCK,CREB5,AKAP12,ANKRD44,OSBPL3,KIAA0040,APPL1,GREB1,CFAP61,KIAA0408,RIPOR2,ZFYVE16,LONRF1,IST1,DGKB,SCRN1,GIT2,ARMCX2,ZNF804A,ZEB2,ZBTB24,ELMO1,CEP170,SRGAP3,NTM,ZNF582-AS1,DLG2,GRIN3A,RAB39B,HS3ST4,OLIG1,HS3ST2,USP3,NR1D2,CPEB2,SLC12A6,DSCAM,ECM2,DNM1L,ABCC9,EBF1,WDPCP,EDN1,SYT15,CNNM1,SEMA3D,KLHL5,TMTC1,MRO,MBNL2,KMT5B,EGR3,GOLGA7,EN2,EPHA5,DENND4A,NCALD,CEP85L,ZNF549,SPEG,ETV1,RTN3,CLVS1,ZNF461,EFEMP1,FKTN,FGFR3,PRKAG2,POLK,SUCO,ATP5PD,SYNCRIP,SEMA4D,FLT1,ANKFY1,SGIP1,NOP56,EFCAB2,NPTN,ZNF605,KHDRBS3,DACH2,SARAF,OGA,FYN,MEGF10,GABRB1,GABRG1,GABRG2,RAPGEF6,SIGLEC8,DISC1,WASF3,ADAM28,LYVE1,GLRB,MSL3,ZNF638,GNG4,GPT2,ADGRA3,GPM6A,TMEM121B,PCLO,GRIA4,KIF3A,FAM19A2,IGSF21,ARHGAP19,HLF,VSIG4,ACOT7,AGFG1,HSF2,IRF8,SOWAHA,IL12A,KCNC1,KCNK1,CREG2,KLRC2,LIG4,SYTL4,ARHGAP12,SYT9,CHIC1,LDLRAD3,MEF2C,MIA2,MITF,AFF1,XRRA1,CD200,ERICH3,GIT1,N6AMT1,CTNNA3,RSPO2,LAYN,NEXMIF,NAP1L1,NF1,OTOGL,ALDH1L2,NHLH1,VWA2,NOS1,NOVA1,SMIM11A,OCRL,OPCML,OPHN1,PAH,PBX1,PDE3B,PDGFRA,GNG2,PFKFB2,CDK14,PIK3R1,SNX10,PLCB2,MTRF1L,PMP22,SCHIP1,ING3,RETREG2,POU6F1,VSTM2L,HYDIN,PRPSAP2,CYBC1,DEF8,PSMD13,CNTLN,UHRF1BP1,BDNF-AS,SPDL1,OCIAD1,PTPRD,PTPRN2,ZNF615,CEP97,TMEM255A,FAM66C,ZNF493,BSDC1,REV3L,GTDC1,FIGN,RNF220,RIC8B,SETD5,EXD2,ALG9,CARF,KIRREL1,ROBO2,BAALC,RPS20,KCNIP1,RXRA,RYR3,S100B,AMER2,MIR124-2HG,SEMA6D,ELMOD1,SFPQ,SUPT20H,ITSN1,SH3GL3,PPM1E,DOCK10,NTNG1,SHMT2,FNDC3A,FHOD3,DZIP1,SLC1A3,FAM81A,SLC6A1,SLC8A3,ARHGEF40,SHANK2,SLC14A1,SLCO1A2,CPEB4,ABTB1,MAST1,SORCS3,SMARCE1,ANKRD36,KIF13A,FAM126B,UNC80,DOP1A,SOX5,SP4,KDM4C,UNC5B,PEG10,C11orf87,PBLD,POGZ,COLGALT2,STOX1,SSPO,ELOVL4,JMJD6,FNDC9,C3orf70,ANKRD28,TACR1,CAMTA1,FAM208A,FBXW11,ANO4,ATMIN,TCF7,DOCK9,TNS2,TEX15,SIRT1,DICER1-AS1,MTMR14,PRRT1,CDK20,AMACR,DCBLD1,ANO5,FAM155A,GORASP1,DNAJC12,FLRT2,BCL2L13,VLDLR,BEST1,P2RY12,CLDND1,RICTOR,KCNK12,ZBTB14,ZIC2,FMN2,TCEAL7,ZBTB16,REEP1,FSTL5,SMARCAD1,CA10,CADM2,DNALI1,CSDE1,EVI5,STOX2,PRDM10,CIAPIN1,CAB39L,FAM47E,MPPE1,PDSS2,GOPC,FZD3,DOCK8,PHTF2,FBXO36,FAM219B,JMJD1C,ZNF248,IFT88,SOCS4,GAN,JPH3" MicroRNA hsa-miR-4287:mirSVR_lowEffct hsa-miR-4287:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.25E-154 2.39E-150 1.30E-152 1.20E-151 407 1754 "TTYH1,SDE2,KCNH8,FAM43B,GALNT16,PWWP2A,ADRA1D,BEND6,AP2A2,KLHL13,PCDH19,WDR35,AK2,ADGRF5,SEMA6A,PCDH10,MRTFA,PDZD4,ANK1,USP28,CNTNAP1,APBA2,APBB1,KCNAB2,CACHD1,AQP6,SEMA4G,SPTBN4,ARRB2,ASTN1,DDX3Y,ATM,ATP1A2,ATP2B1,NOL4,TTLL9,BCL2L2,DNAJC27-AS1,NRP2,BTK,SCAPER,CACNA1I,CFAP410,CA12,CACNA1B,CACNA1E,CACNB2,CABP7,CALM1,KALRN,CAMK2B,TRIM41,CBR1,MTMR7,CDC42,IGFN1,UBE2L6,CFL2,FOXN3,CHN2,CASC2,KMT2C,RAB33A,CLU,FBXO7,QKI,TMEM184B,SRP14-AS1,LY86,ARMC8,SUMF2,AKAP5,IFFO1,ZNF521,CLOCK,CREB5,ANKRD44,CSF2RA,SEC24C,LRIG1,FEZ1,ARHGEF10,CSNK1E,FAM169A,DZIP3,PLCXD3,CFAP61,CCDC144A,NOS1AP,HDAC9,AIF1L,SPATA2,JAKMIP2,ZBTB24,MFAP3L,COPS7A,KIAA0319,BLOC1S6,SNAP91,DLG2,DLG3,DLG4,NYAP1,DNAH9,RPS6KL1,NR1D2,CDON,ACOT8,ABCC5,EBF1,USH1C,EDN1,FAM135B,HEYL,FSD1L,EFNB3,CELSR3,PHF20L1,APH1A,SORBS3,EIF1,EMX2,ERBB2,PIPOX,RASL12,MRVI1,CLVS1,RPS6KC1,ACSL4,FCGR3A,TOMM40L,ZNF589,PRKAG2,CAP2,FOXF2,PCYOX1,FLT1,SGIP1,SLC37A3,NBEA,TACC2,USP16,RASL10A,KHDRBS3,NSG1,KBTBD12,B3GAT1,NRG3,TVP23A,OGA,GABRA2,GABRB1,GALNT15,HBS1L,JPH4,SEPT9,INPP5K,MYOZ2,GCK,GCNT2,CYP46A1,GFER,GGT7,RND1,GLYR1,TOX3,ZNF638,KDM2B,RAB40B,GNAS,GPD2,GPR19,TMEM121B,RAPGEF1,GRM5,GRM7,KIF3A,TMEM25,PSIP1,RNFT2,GPR45,ATXN2L,MIER3,HLF,AGBL5,HMX1,ZNF491,TLX1,USP51,CPT1C,SMAP1,EID2B,IRF8,FAM95B1,C2orf72,IL12A,ITGAV,JAK2,KCNA4,KCNH2,KCNJ9,KCNJ10,KCNK3,KCNMA1,KIF5A,KIF5C,LRRC4B,VWA5A,ARHGAP12,CLEC18A,MAN2A2,MAP6,MAPT,MAT2A,MBD1,ADAM11,MDFI,MEIS2,MGAT3,XRRA1,MN1,CD200,SAMD14,LYRM9,MYO7A,MYO9A,NEXMIF,NF1,NOVA1,DNHD1,SLC11A2,NUMA1,ODF2,OPCML,LOC100128398,ZDHHC22,PBX1,PCDH9,PIRT,PDYN,PFKFB3,PFKFB4,TMIE,PIK3CD,ZNF655,FAM216A,PLP1,PRIMPOL,PNMA3,PMP22,SLC36A4,TATDN3,PTPA,PPP3CA,PRKACB,GRAMD1C,HYDIN,SNRK,WDR25,UHRF1BP1,BDNF-AS,PTPRB,FAM120C,PTX3,RAB5B,CEP97,RAD51D,ZNF793,NWD1,ARID4A,RADX,ZDHHC14,BSDC1,ZMAT4,RGS3,RGS12,KIF7,SEC61A2,DCUN1D2,SETD5,MYH14,TMEM206,HUNK,RTKN,KCNIP2,KCNIP1,CLIP1,RXRA,ZNF331,FAM182A,DGLUCY,MIR124-2HG,CSRNP3,HOGA1,SCN3A,FNIP1,GALNT10,SCG5,ITSN1,SH3GL3,FRMPD1,ARX,ST3GAL3,ANKRD6,WDR37,ZNF365,SLC1A3,SLC1A7,PPP4R3A,SLC6A7,SLC6A8,SLC8A2,YPEL4,SLC11A1,SLC14A1,NAPB,BTBD7,ATF7IP,CPEB4,SMARCC2,MYH15,KIF13A,SNRPN,UNC80,SCN3B,FAM219A,WDTC1,SOX11,IZUMO4,KDM4C,PEG10,ZNF423,KIF1B,DDN,NFASC,SRPK2,CAMTA2,SS18,PHLDB1,GANAB,GSE1,ARHGEF9,VPS13A,PLCB1,TACR1,MTCL1,PJA1,CAMTA1,TAL1,FBXW11,KLHL4,WSCD1,SATB2,TRIM2,RPGRIP1L,TCF12,SYNE1,PHF24,RALYL,PCDHB7,GPRIN3,SIK3,RNF216P1,FAM200B,SIRT1,AP4E1,ZNF106,ARL10,TLR4,ZFP91,RBFOX2,SEZ6L,ZNF384,RUNDC3B,ZMYND8,LRTM2,CLHC1,TMEFF2,MEAF6,VSNL1,TSPAN11,XPO1,SF1,PCDH20,MICU3,CELF4,ZBTB38,ZBTB16,FSTL5,TMEM198,ZNF189,PCBP1-AS1,PMEPA1,PRDM2,PRDM8,XKR7,HPS4,CIAPIN1,WNK3,UBE3B,KAT6A,FAM219B,IFT88,DPF3,ST8SIA2,GAN,SENP7" MicroRNA hsa-miR-384:mirSVR_lowEffct hsa-miR-384:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.33E-154 2.99E-150 1.62E-152 1.49E-151 409 1772 "ABHD6,C3orf14,NBAT1,SYS1,ADAR,GALNT16,DSCAML1,SLITRK1,ADCY6,AXIN2,SORCS1,ERMN,BEND6,GPR158,PCDH19,KCTD16,HACE1,KIAA1324,OSBPL8,AK2,CEP126,ABCD2,ARHGAP20,GOLGA7B,FAM135A,ZFAT,LRCH2,EP400,CCDC146,TNRC6C,APP,AQP4,MIER1,ZFYVE28,PDE8B,ASGR1,MARCH3,CAPRIN2,BRINP2,NUMB,ASTN1,ATP1A2,N4BP2L1,RIPK1,ADAM23,CFLAR,KSR1,SCAPER,CASTOR3,CACNA1I,LURAP1,KALRN,PTBP2,CAMK2G,ISPD,SPAG9,MAP7,ZNF501,INA,P2RX6,ARHGEF2,SEPT7,LOC730101,NOG,SRSF11,FOXN3,CASC2,MS4A7,SYNPR,TAOK2,RAB28,PLAA,CLCN4,ABCG2,CNN3,ARHGEF6,CNR1,AKAP6,SUMF2,LETMD1,BAG4,RBM39,ANKRD44,GDA,SNCAIP,FEZ1,SUSD5,PDE4DIP,CNTNAP2,CST3,PLXNA4,FAM169A,SLITRK5,UBXN2A,CTNND2,NRSN1,RIMS2,DCAF4,HDAC9,ARHGAP32,DCAF8,RIMS3,KCTD8,DGKB,SCRN1,ARMCX4,MYEF2,MFAP3L,HP1BP3,FBXL5,KIAA0319,CEP170,MAGI2,ZC3H11A,ALKBH8,SNAP91,SRGAP3,SGSM2,RABGAP1L,TMCC2,WDR20,GRIN3A,DMD,DMPK,SLC12A6,ATN1,PDCD6IP,FAM78B,ABCC5,DNM1L,ABCC9,E2F5,WDPCP,ANKRD46,SGK2,SEMA3D,TMTC1,YAF2,PHF20L1,ABI2,GOLGA7,SORBS3,TENM1,DCTN4,EPHB1,CEP85L,SPEG,CDHR1,MRPL10,DNAJC27,EXTL2,NSRP1,CACNG3,TMEM132C,ATP8A1,CEP78,ZSCAN30,GTF2IRD2,FGF14,TMEM164,POLK,MEX3B,IQCG,FOXO3,SLC37A3,NBEA,UFM1,PDLIM5,KHDRBS3,NSG2,DACH2,STAU2,SARAF,NRG3,ZNF512,GAB1,GABRA1,HRASLS5,GABRA5,TRAF3IP2,HBS1L,ZMYND11,IQGAP2,ERAP1,ZNF559,C15orf41,DISC1,ATP8A2,GATM,SULT1C4,CYP46A1,GFRA2,GLDC,TNRC6A,ZNF638,RAB40B,LOXL3,GPR12,CCDC184,GPR34,CECR2,PCLO,ATP2B1-AS1,PLCD4,GRIK1,LINC00839,RASSF8,HAS2,BACH2,HNMT,HNRNPK,ZDHHC15,SMAP1,ATCAY,FAM95B1,DOCK7,SCIN,ZNF385B,LRRTM3,JAK2,SLC35G1,KCNB1,KCNJ9,KCNK3,KCNQ3,CREG2,KIF5A,KIF5C,STXBP5,LIFR,LIG4,PAXBP1,MAP2,MAP6,MARK1,MATN3,MBD1,MBNL1,MEIS1,MEIS2,MKLN1,MOBP,CD200,MYO6,MYO9A,ZNF862,NASP,ZC3H12B,CNOT4,NOVA1,NTRK2,NUCB2,OPHN1,PAX6,DPY19L2P2,PCMT1,PDE3B,PDE4D,PDGFRA,GPR85,CDK14,NLGN3,RETREG1,GPSM2,PLCL1,FTO,TNPO2,POU3F2,PCDHB17P,RANBP3L,RASGEF1B,PRKCZ,EPDR1,MASP1,GON4L,MDGA2,CNTLN,MTMR10,SPDL1,OCIAD1,EML5,PEX5,TTC13,TUG1,PPP2R3C,RASGRF2,DBX2,KHDRBS2,SLC6A15,RGS10,RLBP1,RNASEL,ROBO2,PCMTD2,CCDC102B,RPE65,TMEM100,SPIN3,ATAT1,WLS,ZNF568,RMI1,CSRNP3,SCN2B,LINC00461,SCP2,SUPT20H,TRA2B,ZFP30,ITSN1,SH3GL3,PPM1E,CPEB3,HKDC1,FBXO11,SLITRK3,ST3GAL3,SEC31A,SLA,ZNF365,SLC1A3,SLC2A5,PKNOX2,RAB3GAP1,SLC12A2,ZNF334,SCMH1,ZFP1,SMARCE1,RCOR3,MAPKBP1,MBD5,BDP1,TSNAXIP1,SP4,NMNAT2,HECW1,KDM4C,RBM26,SPART,ATP10B,CLASP2,CLSTN2,ITPRID2,SS18,STAU1,ZSCAN29,SEPT3,FGD4,VPS13A,C3orf70,SYPL1,COBL,SLC37A2,CAMTA1,ADGRL3,ZFP90,CUX2,TPCN2,TCF12,NAT16,RALYL,NSD1,GPRIN3,AHCYL2,TEX15,RNF216P1,HHIP,THRA,GZF1,TJP1,TLR4,ERCC6L2,FAM124A,BEX4,PRRT1,RBFOX2,RASD2,SYNPO2,TRH,ELP5,RUNDC3B,TRPS1,TSC1,SSBP2,ZKSCAN5,HIRA,BCL2L13,VGF,WIPF1,ZNF24,KCNT2,ZNF540,GPR158-AS1,LYPD6,ZNF154,ZFAND5,SLC30A4,STOX2,PCDH15,PLSCR4,DOCK8,FBXO36,RNF170,SSPN,FXR1,IFT88,SLC4A10,PRRT4" MicroRNA hsa-miR-647:mirSVR_lowEffct hsa-miR-647:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.43E-154 3.05E-150 1.64E-152 1.51E-151 402 1713 "EMILIN3,SLC25A25,GALNT16,PSMG3-AS1,ADCY6,SORCS1,GRAMD1B,PTCHD1,FAHD2CP,MTA3,SLC24A4,AP2A2,AP1B1,HACE1,SPOP,FAM135A,KCNT1,AMPD3,DPP10,EP400,PPFIA1,PKP4,TNRC6C,SPTBN4,ASCL1,ASPH,ZSCAN18,NUMB,DDX3Y,DYNLL1,ALDH4A1,STX16,ZNF582,CADM3,ADGRB1,SNAI3-AS1,JAZF1,AP1M1,MMD2,CA8,CACNA1B,CACNA1D,DIRAS1,HAP1,PTBP2,CAST,HIP1R,ENTPD6,ARHGEF2,CDC42,LRRFIP1,MAGI1,UBE2L6,NUMBL,CFL2,CHGA,CHM,ARHGAP22,NRXN3,NGEF,ABCG2,QKI,MAP4K4,CNN3,AKAP6,BTF3L4,SLC4A8,SMARCAL1,SLC35F1,CDC42BPB,SH2B1,SNCAIP,RGS6,SEC24C,VCAN,PDE4DIP,PLXNA4,ZSCAN23,ARHGAP32,KATNAL2,FRMPD4,HDAC4,ZFYVE16,PHYHIP,TMEM170A,IP6K1,GIT2,C8orf34,ZEB2,MFAP3L,RUSC2,COPS7A,LYPD1,POM121,SV2B,SPOCK3,SGSM2,WDR20,DLG2,EXOG,DMD,HS3ST4,DPYSL2,ACOT8,DYRK1A,GOLT1B,E2F6,USH1C,EDNRA,PHC2,SGK2,ABI2,EGR3,AASS,EIF4G2,ELAVL4,STARD3NL,HSD17B14,EPB41L2,LRRC23,ANKRD13B,EFS,ZNF549,CDHR1,DNAJC27,CLVS1,TMEM132C,PTK2B,DLC1,TOMM40L,STRADA,ZNF589,FER,SPSB4,CAMSAP1,POLK,IP6K2,SEMA6C,EVL,DPYSL4,SPECC1,PDLIM5,CELF1,KBTBD12,DKK3,GAB1,GABRA3,ZMYND11,GALC,ZNF274,DISC1,TUBGCP4,SULT1C4,ADAM28,GHR,PPARGC1A,KIRREL3,ZNF276,CRCP,GLI2,GLS,WDFY3-AS2,PCLO,GRB10,ADAMTS13,CIT,BTN2A1,LINC00839,RNF165,TMEM25,SOX21,PSIP1,FAM107A,RNFT2,ATOH8,PADI2,FRMD5,DDX19B,LINC01102,GABARAPL2,HNF4G,HNMT,TCEAL6,DHX35,CELF5,LINC00667,MYLK2,ZNF546,KNDC1,USP54,IGSF1,LIX1,IL11RA,NME9,ITGAV,CDH20,KCNJ3,KCNK2,CREG2,KIF2A,KIF5C,KLC1,L1CAM,STMN1,INSYN2,SYTL4,PIK3AP1,LOC100128239,ZFYVE27,MAOB,MARK3,MBD1,TM6SF1,MEIS2,AFDN,MRPL42,MYO9A,RTL5,NAP1L1,P2RY13,NEFH,NELL1,SLCO1C1,NFIA,NFIX,VWA2,NOS1,DNHD1,NPR2,SLC11A2,NUMA1,TBC1D25,OGG1,OPCML,OPHN1,ZDHHC22,PBX1,CDK18,PDE2A,GNG2,BEST3,GDAP1L1,SSH1,NALCN,CAMKV,ZNF655,XRN1,FTO,PRIMPOL,PNMA3,ANKRD16,CDIP1,SCHIP1,SDK2,PPP3CB,KANSL1,CEP41,PRODH,MASP1,WBP1L,SIDT1,MDGA2,ANKHD1,PTK2,PTPRO,ZSCAN2,NKAIN1,RALGDS,SH3TC2,ZCWPW1,FEZF2,GAL3ST4,RFX2,RFX4,KCTD17,ARHGEF10L,RNF220,PBRM1,RPRD1A,ALG9,ELP2,ZNF671,STX1B,TRAPPC13,FAM192A,SEMA6D,SCN2B,IL17RB,TRIM46,FOXRED1,ITSN1,PPP1R9A,SH3GL3,CHD9,BCAN,ST3GAL3,DZIP1,SLA,SLC1A7,KANSL3,LRRC55,ARHGEF40,SLC14A1,SLC15A2,TMEM132D,SCMH1,ARFGAP1,CDK5RAP2,SMARCE1,RIMS1,KIF13A,CABCOCO1,SNRPN,PDZRN3,KDM4B,DOP1A,SON,WDTC1,TSNAXIP1,DOK5,ZSWIM8,KDM4C,SPTB,POGZ,NKAIN2,INKA2,DIP2A,PHLDB1,SEPT3,PRRC2C,RHBDL3,ARHGEF9,ADAMTS17,SYN2,SYT4,KAZN,MTCL1,SEMA4A,CAMTA1,TAF6,TBCEL,TBX15,TPCN2,RPGRIP1L,SYNE1,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,CRB1,ITGB3BP,GPR161,SLC44A1,TMEM9,ERCC6L2,LRRC8A,RIMBP2,KCTD2,TNFRSF1B,C5orf64,KAT6B,NPL,SYNPO2,ELP5,TRPS1,PPIL6,NTSR2,TTTY15,CADM1,UBE2H,SLC35A4,PITPNB,BEST1,LMF1,XRCC4,LGI4,SF1,ZNF24,CELF4,TMEM198,ANKS1B,PLPPR5,NT5M,RNF103,SEMA3B,URM1,PPP1R3F,PCBP4,MVB12B,DNAH10,RSPRY1,NHSL1,NETO2,RNF146,AP3B2,SOCS4,PRRT4" MicroRNA hsa-miR-335:mirSVR_lowEffct hsa-miR-335:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.32E-154 3.55E-150 1.90E-152 1.75E-151 431 1963 "TTYH1,RBM10,NBAT1,KDM5D,GPRIN1,CSMD3,NDRG3,ADAR,ADCY6,ADD3,PTCHD1,INTS2,KLHL13,RTL9,OSBPL6,AK2,ZNF578,UNC79,GPRASP2,AMPH,OGT,EP400,MAP4K3,USP28,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PARG,MAGEE2,APOC2,API5,PPFIA3,AQP4,MIER1,CASK,TMEFF1,MARCH3,DDX3Y,ALDH4A1,SLC4A4,EIF4G3,ATP2B1,ALDH7A1,MTMR9,BARD1,BCL2L2,MIR9-3HG,BMPR1B,CACNA1G,BSN,CACNB4,CALM1,CAMK2G,RUNX1T1,NFS1,CBS,KRIT1,METTL6,RGN,SCARB1,ENTPD6,ARHGEF2,SEPT7,LOC730101,CLGN,NUMBL,CHGB,CHM,CASC2,MS4A7,EPS15L1,CLTA,CLTC,FADS2,AKAP7,PCYT1B,SUMF2,COL9A1,AKAP5,IFFO1,SMARCAL1,C2CD2,RBM39,CREB5,CRMP1,GDA,CLIP3,FEZ2,SOCS5,PLXNA4,UBXN2A,PLCXD3,GREB1,PUM1,DCAF4,ECE2,BOC,HDAC9,MYADM,ARHGAP32,RIPOR2,ARHGAP24,FRMPD4,EARS2,LIN54,KCTD8,ARMCX2,ZEB2,FBXL5,COPS7A,ALKBH8,SNAP91,SRGAP3,NTM,RABGAP1L,DNM2,DOCK2,DTNA,PHC2,HIPK3,SYT15,CACNG7,EFNA3,EFNB3,CELSR3,FAM13A,KMT5B,KCTD3,EIF4G2,ELAVL2,STARD3NL,DCTN4,ENO2,EPB41L2,RCAN2,RASGRP2,KCNMB2,GPHN,NCALD,APC2,FABP7,CORO2B,CHST15,TOMM40L,ZNF589,MED12L,FGF12,FGFR1,SYNCRIP,RGPD5,SLC37A3,SORBS1,SPECC1,PDLIM5,ERGIC3,KHDRBS3,GPR153,CSPG5,MSANTD4,NRG3,ABLIM2,OGA,GABRA1,AHCYL1,FAM120B,JPH4,DISC1,ATP8A2,ALDH1L1,NFU1,PCDH17,TOX3,TNRC6A,GLUL,DCLK2,GNG4,GPM6B,FUT10,CCDC184,STON1,NUDT21,TMEM121B,PCLO,GRIA4,GRID1,GRIK2,ZNF496,LINC01089,LINC00839,CLASRP,AP4S1,MAP4K5,WIF1,IRAK3,PACSIN2,HLF,ELOVL5,SMAP1,IRF8,MSL1,IDH3A,IL11RA,LRRTM3,ITGAM,ITPKB,OLFM3,KCNH2,KIF5C,IPO5,CYP27C1,LIMS1,SYTL4,HECTD2,NCOA7,LOC100128239,MAOB,MAP2,MARK1,MBNL1,MDM4,LRP1B,MEIS1,KITLG,SCAMP5,MMP16,ERICH3,ADAM22,CTNNA3,MTR,ZNF862,NAP1L1,FXYD6,NCAM1,NDP,SFR1,NEUROD1,NFE2L2,DNHD1,OCRL,P2RX7,PCDH8,PCMT1,PDCD2,PDE4D,PDGFRA,GNG2,PENK,BEST3,CYTL1,PFKFB3,ZDHHC8,NALCN,ANLN,ZNF655,XRN1,FAM216A,PLCB2,SLC25A23,MTRF1L,STRN3,RC3H2,SCHIP1,FAT3,SH3KBP1,POU6F1,PPP1R1A,RAB39A,GRAMD1C,CNNM2,SAMD9,SLC22A23,CYBC1,UHRF1BP1,BDNF-AS,MTMR10,PTN,TMEM260,PTPRB,EML5,TUG1,PPP2R3C,USP47,PLEKHB2,RAD51D,NWD1,OXR1,RASGRF1,ARID4A,KHDRBS2,ARHGEF10L,TTLL7,RIT2,MRPS18A,SEC61A2,RIC8B,NUDT11,CARF,PNMA8A,GSTCD,KIRREL1,ROBO2,CCDC25,YY1AP1,RPE,HUNK,KCNIP3,ZNF354C,NCBP3,FOXRED2,SATB1,HOGA1,SCN2A,LRRTM4,SCN8A,SCP2,RASA3,KIF21A,ITSN1,SH3GL3,PPM1E,DOCK10,FHOD3,R3HDM2,SLA,FAM81A,EPN2,WDR47,RUFY2,SLC8A3,TMEM132D,SPHKAP,LGI3,NAXD,CDK5RAP2,INTS9,SMARCE1,IGSF9B,INAVA,LIMCH1,RBM34,KDM4B,MYT1L,ZNF423,ZC3H13,SPTAN1,NPAS3,C11orf87,ZNF621,TROVE2,ITPRID2,SS18,TTBK2,KANK1,ZC3H4,SYNE2,RHBDL3,PLCB1,SYN2,POPDC3,TACR1,CAMTA1,UNC5D,WWC1,AGTPBP1,TBCEL,FBXW11,TCF7L2,TCF12,SYNE1,PCDHB6,PSD3,GPRIN3,RNF216P1,SIRT1,ZNF106,TIAM1,TJP1,ZFP91,TMPO,RIMBP2,KCTD2,TNR,PIK3R5,C9orf85,RGMB,TRPC3,ZMYND8,RUSC1,TSC1,PRR18,ZKSCAN5,CLHC1,CADM1,DNAJC12,SLAIN1,BCL2L13,MEAF6,LMF1,RICTOR,PCDH20,ZIC3,MICU3,ZNF70,LYPD6,REEP1,POLR3H,FTSJ1,WNK1,EMSY,MFF,PRTFDC1,EVI5,STMN4,RNF103,CIAPIN1,SIGLEC10,WIPF2,WNK3,AMN1,ST7,MARCH8,UBE3B,KAT6A,HNRNPA3,JMJD1C,TTC7A,SSPN,FRMD6,IFT88,GAN,PRRT4" MicroRNA hsa-miR-636:mirSVR_lowEffct hsa-miR-636:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.50E-154 4.77E-150 2.54E-152 2.34E-151 382 1550 "DGCR6,CSMD3,ADCY6,GALNT13,RNF157,SORCS1,BEND6,SLC24A4,AP2A1,GPR158,KCTD16,AK2,TAOK1,ALCAM,CEP126,AMPD2,LCORL,PHF12,PPFIA1,DGKZ,TNRC6C,API5,SHROOM2,SPTBN4,ARRB1,RGS20,CDK13,DNAH17,INSYN2B,RNF182,MYOM1,BCHE,NRP2,ZNF599,ARHGEF7,KALRN,CAMK2B,SLC25A14,VXN,PRC1,CBS,USP2,MTMR7,INA,P2RX6,CD86,SCARB1,TMEM257,LRBA,DCLK1,L3MBTL4,LOC730101,MAGI1,DLGAP2,TIGD7,CFL2,ADGRG1,SRSF11,CHN2,CASC2,NRXN1,ABCG2,FHL5,CNTFR,CNTN1,IQCK,LETMD1,SLC4A7,CNRIP1,SEC31B,C2CD2,CRYM,MROH8,SNCAIP,CSF1,RGS6,ARHGEF10,MICAL2,OSBPL3,ATRNL1,PDE4DIP,CNTNAP2,PLXNA4,DZIP3,CCDC144A,HDAC9,ARHGAP32,RIPOR2,KIF26A,RIMS3,IP6K1,DBN1,ELMSAN1,JAKMIP2,ZNF804A,ZEB2,KIAA0319,CEP170,MAGI2,ZC3H11A,RHOBTB1,SMG7,SPOCK3,SEC16A,DLG3,DMD,HS3ST4,DMTF1,DTNA,DTNB,MAMLD1,DYRK1A,EBF1,EDNRB,FAM13A,PHF20L1,KMT5B,GOLGA7,EIF4G2,SORBS3,COPS4,RGS17,ELN,PAN3,VPS13B,EPB41L1,LRRC17,EPHA5,EPS8,CD320,ZNF461,CACNG3,TMEM132C,EFEMP1,FDFT1,GORAB,FER,MED12L,FGR,HPCAL4,CAP2,FOXF2,USP16,APOPT1,ARFGAP2,ZNF605,HHIPL1,NEURL4,DKK3,GABRA2,HRASLS5,GABRA3,JPH4,GCNT2,TUBGCP4,MALT1,LYVE1,TOX3,TNRC6A,PCDH11X,ZNF638,GNAS,GNG4,PSRC1,ADGRA3,GPD1,GPR12,RAPGEF4,GRIA1,RFFL,ADAMTS13,GRIN2D,TMEM25,SOX21,MAP4K5,HSF2,SHISA6,IRF8,PLD5,IGSF1,IL6ST,SLC6A17,ITPKB,KCNK1,KCNK2,KCNN2,KCNN3,KIF2A,STXBP5,INSYN2,LIFR,PAXBP1,NAT8L,MARK1,EFHB,LRP1B,MEF2C,MEIS1,MEIS2,SCAMP5,POC1B,MITF,AFDN,WDR49,MOG,ERICH3,CTNNA3,MYO7A,RTL5,P2RY13,NEUROD1,NFE2L2,NFYA,NNAT,NODAL,NOVA1,LRIT2,NRGN,NTRK2,NUCB2,ODF2,OGG1,OPCML,SNTG1,CNTN3,PCDH8,PDYN,GPR85,SERPINI1,NALCN,ANLN,SLC25A23,HMGCLL1,PACSIN1,POU3F2,MINDY2,PCDHB17P,PPP2R5E,RASGEF1B,RAB39A,EPDR1,HYDIN,PRPSAP2,BCAS3,MDGA2,WDR25,ELOVL2,PXK,RAB3IL1,PID1,ENOX1,DBX2,VEPH1,KHDRBS2,RDX,ZYG11B,ZMAT4,RGS12,RNF220,RNASEL,CARF,ROBO1,ROBO2,UEVLD,ACER3,RPS6KA2,LGR4,SARS,SATB1,ATXN2,ATXN7,LRRTM4,SCP2,ASIC4,GALNT10,SUPT20H,ITSN1,SH3GL3,SHC4,FBXO11,FHOD3,SLITRK3,WDR37,ABLIM3,ZNF365,BTBD3,SLC6A1,CCDC88A,SLC12A2,SLCO1A2,TET1,COA1,SMARCD3,INTS9,SMARCE1,FAM126B,USP33,SOX1,SOX2,KIF21B,FNBP1,UHRF1BP1L,MYCBP2,ERC1,PEG10,LMO3,TAB2,STOX1,LRRC4,ST5,CEP68,SULF2,SEPT3,STXBP1,GSE1,NSFL1C,ARHGEF9,VPS13A,DNAJC9,PLCB1,TMEM150C,SYPL1,SYT1,COBL,ANKRD28,TAC1,SEMA4A,DNMBP,UNC5D,TMEM136,ATMIN,TCF7,TCF12,CLASP1,WDR7,SYNE1,RALYL,FAM200B,ZFPM2,LEFTY2,AP4E1,GPR161,CDH22,ACTR6,NR2E1,TRIO,STXBP4,TUB,TMEFF2,HEPACAM,UBE2H,UGT8,VLDLR,ZFP37,ZNF711,ZNF17,ZNF23,NDRG4,CELF4,TMEM237,ANKS1B,CADM2,PRDM2,RGMA,CSDE1,STMN4,PRDM8,PRDM10,RNF103,TMEM178A,URM1,TMEM163,LINC00632,SLC17A6,UBE3B,PAK5,TMEM63C,JMJD1C,NLRP3,SLC39A12,SSPN,LAS1L" MicroRNA hsa-miR-1915:mirSVR_lowEffct hsa-miR-1915:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.77E-154 4.93E-150 2.61E-152 2.40E-151 404 1732 "CPNE2,TTYH1,ABR,SYS1,ACTN2,FAM43B,CSMD2,GPRIN1,NDRG2,TMEM132B,GALNT16,SLC12A5,CDC7,PNMA8B,ERMN,ADRA1B,MTA3,AP1B1,OSBPL1A,SORCS2,DISP3,MRTFA,AMPD2,EP400,MYH7B,PPFIA4,CNIH2,APBB2,APLP1,BCAS1,AQP6,MADD,SPTBN4,ARHGDIG,ARNTL,PLA2G4C,CCDC74A,ZSCAN18,PCDHGB4,ATP1A3,SLC2A11,N4BP2L1,ADAM15,SEC11C,RGS9,CDK5R1,ST3GAL5,SYNJ2,CACNA1I,MYRF,CA4,CACNA1D,CACNG1,KALRN,PTBP2,CAMK2A,TRIM41,SYT6,PRC1,SCARB1,ARHGEF2,CDC25B,CDC27,ZBED1,CDH18,TBRG4,GPR37L1,PLEKHB1,CASC2,JAM2,TAOK2,EPS15L1,CPNE6,RAB28,PPT2,NRXN2,SLC24A2,CLTA,ABCG2,TMEM184B,IGLON5,ARMC8,SLC4A8,SMARCAL1,ZNF521,SLC35F1,SNCAIP,MICAL2,SUSD5,IPCEF1,RIMS4,CST3,CTNND1,PUM1,ECE2,ARHGAP32,DAPK3,DBN1,ELMSAN1,DGCR5,ZEB2,TIAM2,COPS7A,MAGI2,LYPD1,SV2A,DLG3,DLG4,DMPK,OLIG1,RPS6KL1,DPH1,CASP8AP2,FAM57B,GNE,DTNA,DNM1L,PHC2,SGK2,FRY,EFNA3,APH1A,EIF4G1,EIF4G2,SORBS3,ELN,SEZ6,ZNF549,MRVI1,NRN1,F5,WAC,ACSL4,TUBB3,CORO2B,ZNF589,FGF12,HPCAL4,CAP2,IP6K2,FOXO3,FLNC,NOP56,SYT3,SORBS1,SPECC1,ARFGAP2,ERGIC3,KHDRBS3,CELF1,CGREF1,TMEM151A,GABBR1,GABRB1,TRAF3IP2,FAM120B,B4GALNT1,JPH4,TMEM8B,ACSS1,KIAA1841,GCK,TUBA8,SRCAP,ADAM28,GGT7,HEPN1,TOX3,STARD3,PCSK1N,GPD1,TDRKH,CCDC184,RAPGEF4,GRIA1,GRIN2C,PRDM5,LINC01089,LINC00839,KAT7,MFSD2A,FAM107A,ADAMTS6,SLC2A6,BACH2,HAPLN2,SYNPO,HMGCL,TLX1,TCEAL6,HSD17B1,IDH3A,C2orf72,IGF1,SLC35G1,METTL21A,KCNC1,KCNH2,KCNJ5,KCNMA1,KCNN1,KCNN2,KIF5C,LINC00634,A1BG-AS1,CYP27C1,CAMK2N2,LSS,PACRG,CLEC18A,MAN2A2,MAP4,SRSF12,SCAMP5,ERICH3,JAKMIP3,PTOV1,RSPO2,C10orf105,MXI1,MYCN,MYT1,NEFM,NODAL,NPTX2,NUMA1,GPR88,OGDH,OGG1,OPHN1,ZDHHC22,PCDHGC3,PDE4D,PDE1B,GNG2,PFKFB3,DUSP26,NLGN3,ZNF655,ZFYVE21,PLCD1,EPN1,PLXNB3,ANKRD16,CDIP1,SCHIP1,SEPT4,TNPO2,FAT3,POU6F1,PPP3CB,PRKCB,MAPK10,DIRAS2,MASP1,NDUFS7,SLC22A23,SIDT1,GON4L,SNRK,PIGG,CNTLN,NCR3LG1,OCIAD1,RIPOR1,NKAIN1,TUG1,TMEM231,RAB3A,RAB5B,USP47,ZYG11B,GTDC1,KCTD17,RNASEL,RPRD1A,RNH1,DCUN1D2,EXD2,C12orf49,RAVER2,CYB561D1,KIRREL1,EPHA10,BAALC,KIAA0895L,TCP11L1,MEG3,ATAT1,KCNIP3,DGLUCY,MAPK12,SBF1,CSRNP3,SCN2B,HES6,SLC30A10,TRIM46,SHMT2,BCAN,SLA,RPH3A,PKNOX2,SLC6A7,SLC6A8,SLC8A2,YPEL4,RADIL,SLC8A3,ARHGEF40,SLC9A5,KBTBD4,TMEM132D,ELMO2,SORCS3,IGSF9B,INAVA,FAIM2,SNRPN,BDP1,KDM4C,SPTB,IQSEC2,SMOC1,STAC2,GANAB,STXBP1,NSFL1C,SUPT5H,MMS19,TAL1,TBCEL,FBXW11,TMEM136,NEU4,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,OBSL1,TNS2,ARHGAP9,HIF3A,CYB561A3,PMS2CL,LEFTY2,FBXL16,GALNT17,ARL10,MTMR14,TLR4,ZFP91,NR2E1,LRRC8A,TNFRSF1B,NPL,IL34,ZNF346,TRPM2,RUSC1,KCNE5,TSC1,SGK3,RPRM,UBE2H,OSBP2,FLRT2,CLIP2,NSD2,WNT7A,SLC47A2,PCDH20,ATP6V0E2,PLPP4,GPR158-AS1,ZBTB16,EML6,FTSJ1,ZNF213,MEIS3,DHX33,HPS4,SEMA3B,PCBP4,HRASLS,NUP214,ZDHHC20,NETO2,SOCS4,ST8SIA2,LAS1L,PRRT4" MicroRNA hsa-let-7c:mirSVR_lowEffct hsa-let-7c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.92E-154 5.57E-150 2.93E-152 2.70E-151 413 1809 "GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,RTL9,OSBPL1A,TXNDC16,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,CDC42BPA,ANK1,ANK3,LCORL,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM23,ADAM15,SNAI3-AS1,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,NFS1,USP6,CD86,LRBA,LRRFIP1,L3MBTL4,TIGD7,CLGN,NUMBL,CACNA2D2,ASIC3,MS4A7,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,DCT,ZBTB24,MFAP3L,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,GRIN3A,CPEB2,DOCK2,DMTF1,DPH1,PDCD6IP,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,SNX29,EDNRB,ANKRD46,RBM12,YAF2,EFNB3,EBI3,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,EPB41L2,COQ7,DMTN,EPHB1,ANKRD13B,RABEPK,CDHR1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,CHST15,TOMM40L,GTF2IRD2,CAP2,IP6K2,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,SIGLEC8,DISC1,ATP8A2,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,OPALIN,LRRC75A,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,MYO9A,RTL5,PABPC1L2A,NDUFA5,NEFM,NELL1,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RX7,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PLCB2,PLP1,HMGCLL1,C11orf49,TRHDE,SCHIP1,RANBP3L,RAB39A,PKN2,MAPK4,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,TMEM260,PTPRD,CASTOR1,PTPRG,FAM120C,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,TRIM68,KCTD17,RIT2,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,SPIN3,KIAA0895L,ACER3,TCP11L1,PTGR2,MEG3,TRAPPC13,ATXN2,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,FOXRED1,HSPA4L,ITSN1,CPEB3,ST6GAL1,WDR37,SLC1A7,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,SLC6A8,KDM4D,SLC8A2,ATF7IP,CPEB4,MAST1,SMARCD3,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,NFASC,TAB2,CLSTN2,POGZ,SSTR2,SYT11,MLC1,FNDC9,PLCB1,TAC1,PDLIM2,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,DICER1-AS1,AP4E1,FBXL16,ARL10,ERCC6L2,DAAM2,KCTD2,TNFRSF1B,C5orf64,NPL,CHST5,SMUG1,TRIO,STXBP4,TRPC3,NTSR2,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF28,ZBTB38,ZBTB16,MEIS3,WNK1,CSDE1,SIGLEC10,FIP1L1,TRIM16L,ST7,UBE3B,KAT6A,CASC15,NUP214,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-623:mirSVR_lowEffct hsa-miR-623:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-153 6.40E-150 3.35E-152 3.09E-151 417 1844 "DPF1,TTYH1,SDE2,ABAT,SYS1,ARID1A,NDRG3,ADAR,SLC12A5,PWWP2A,KIAA1211,ADORA3,RNF150,FAHD2CP,KIDINS220,AP2A2,INTS2,PCDH19,AK2,SEMA6A,SPOP,ABCD2,BEGAIN,AMPD3,AMPH,KIF6,DPP10,EP400,CCDC146,USP28,CNTNAP1,UPRT,GPAM,API5,AQP4,AQP6,MIER1,PDXK,IGDCC4,SPTBN4,ARHGDIA,ARRB2,BRINP2,NUMB,ASTN1,SLC4A4,ATP2B1,DPY19L3,ADAM23,SNAI3-AS1,LINC00847,SEC11C,BCL2L2,JAZF1,GYG2,OSGIN2,LDLRAD4,CACNA1A,CACNA1D,CALM1,PTBP2,CAMK2B,TRIM41,VXN,SLC16A4,TMEM257,CDK11B,REPS2,IGFN1,UBE2L6,CFL2,CHGB,CHN2,RAB33A,CLCN3,TPP1,DNAJB5,AKAP7,IQCK,PCYT1B,ARMC8,FAM149A,COL4A5,SLC25A27,SUMF2,SMARCAL1,CLOCK,C2CD2,RBM39,NCOR1,GDA,MROH8,MICAL2,CSNK1E,ATRNL1,SIPA1L1,PLXNA4,DZIP3,CFAP61,CTNND1,DCAF4,CCDC144A,BOC,DCAF8,TOX,EARS2,LONRF1,DGKG,SCRN1,BRINP1,SPATA2,ZEB2,MED24,KLHL3,BLOC1S6,ZNF582-AS1,DLG3,DNM1,SLC29A4,DMTF1,DPYSL2,SLC25A18,DRD1,ACOT8,DNM1L,EBF1,SNX29,FAM135B,EEF1A2,SGK2,HEYL,FRY,SIDT2,EFNA3,EFNB3,MRO,AASS,TENM1,ELAVL2,CALCRL,RCAN2,SRRM1,NCALD,CEP85L,ZNF549,CDHR1,DNAJC27,RCSD1,ADGRV1,WAC,ACSL4,ZMYND10,PRMT5,KAT8,GTF2IRD2,KIAA1109,FGF14,POLK,SUCO,HPCAL4,CAP2,FOXO3,SEMA4D,ATP13A4,FLT1,SGIP1,SLC37A3,NBEA,SORBS1,SPECC1,PDLIM5,FAM49B,ATP6V1H,KHDRBS3,NRG3,ABLIM2,OGA,GABRA2,GABRG1,FAM184B,GAD1,HBS1L,ERAP1,SEPT9,DNER,MYOZ2,GFRA1,USP19,GGT7,HEPN1,ZNF276,RND1,COPS8,GLYR1,RAB30,GLRB,TOX3,TNRC6A,GLUL,ZNF638,KDM2B,LUZP2,RAB40B,GPM6B,SPACA9,SERP2,KIF3A,FAM19A2,COQ10A,IL1RAPL1,AP4S1,GUCY1A1,IRAK3,HAS2,FRMD5,TNFAIP8L3,HMX1,TLX1,CPT1C,OPALIN,DHX35,SMAP1,IRF8,FAM95B1,MYLK2,IL12A,ZNF678,INPP5B,INSM1,JAK2,KCNA4,GPR62,KCNK2,KIF5A,STMN1,INSYN2,HECTD2,FGFBP3,MEF2C,MGAT3,MID1,AFF1,AFDN,CD200,MT1M,MTTP,MXI1,MYO7A,MYO9A,NCAM1,NFYA,DNHD1,SLC11A2,NRCAM,NTRK2,NTRK3,ODF2,LOC100128398,OXTR,PBX1,PCDH9,PCSK5,CDK18,PDGFRA,NLGN3,TMIE,ZNF655,A2ML1,FAM216A,PLCL1,C11orf49,ANKRD16,LRP12,SLC36A4,NXPH1,POLR2F,DRAM2,MINDY2,PPM1B,CRLS1,PPP2R5E,PRKAB2,PRKCB,MAPK4,EPDR1,MAPK9,PROX1,MASP1,CNNM2,PIGG,NCR3LG1,OCIAD1,PTX3,CEP97,ZNF793,RADX,ZDHHC14,BSDC1,ZMAT4,DPF2,RGS12,KIF7,SEC61A2,RNF220,RIC8B,ZFHX4,ROBO2,TMEM206,FBXW7,SGSM1,ADAL,SYNDIG1,SCN3A,PRCD,SLC30A10,ZNF821,ASRGL1,TRA2B,ITSN1,SH3GL3,FRMPD1,ARX,FERMT1,KIF16B,NTNG1,AMBRA1,SEC31A,SLC1A3,SLC1A7,KANSL3,SLC8A3,CCDC88A,SLC14A1,ATF7IP,MYH15,SNRPN,SON,MYT1L,BDP1,CLUAP1,ENKUR,HECW1,MYCBP2,KDM4C,ZNF423,KIF1B,SPART,NFASC,C11orf87,ATP10B,SS18,ERBIN,ZSCAN29,DIP2A,ADHFE1,SEPT3,NSFL1C,VAMP1,ARHGEF9,MTCL1,PJA1,CAMTA1,ANO4,VWA3A,CUX2,ZEB1,TPCN2,SYNE1,NAT16,DOCK9,RALYL,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,SIRT1,C18orf54,ZNF106,ZFP91,PRMT8,AMACR,ZMYND8,FNDC5,TSN,ANO5,TTTY15,CADM1,AMOT,BCL2L13,VSNL1,GUSBP1,SF1,MICU3,FMN2,ZBTB16,POLR3H,ANKS1B,DHX33,SLC38A1,GDPD5,PRDM8,TMEM178A,MVB12B,FAM13C,FZD3,MARCH8,UBE3B,FBXO36,FAM219B,ZNF248,SSPN,SLC4A10" MicroRNA hsa-miR-432*:mirSVR_lowEffct hsa-miR-432*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-153 6.55E-150 3.41E-152 3.14E-151 373 1479 "ABCF1,SYN3,ACTN1,CSMD2,CSMD3,NDRG3,TMEM132B,ADCY2,KLRC4,RNF157,SLC12A5,CDC7,ADORA2A,KIDINS220,AP2A1,AP2A2,MTUS1,RTL9,LRRC7,SPOP,FAM135A,KIF6,ZFAT,OGT,SEMA7A,PI16,CNIH2,APC,APLP1,GPAM,LGR5,MIER1,ARHGDIA,ASPH,PCDHGB4,ATP1A1,ZNF583,ATP6V0A1,BACH1,CFLAR,CACNB2,HAP1,PTBP2,CAMK2B,SPAG9,NFS1,CBR1,MTMR7,ZBED1,CDC42,LGI1,LOC730101,UBE2L6,FOXN3,CASC2,CLCN4,COG1,ARHGEF6,CNTN1,BTF3L4,ABI3BP,COX4I1,SMARCAL1,MFSD4A,CHD1L,ZNF385A,CLOCK,PREPL,CREM,NCOR2,GDA,CSF1,RGS6,CSF3R,SOCS5,CNTNAP2,CTNND2,ST18,NOS1AP,CYBB,KATNAL2,PHF19,ZNF337,MATR3,CTIF,GIT2,ARMCX4,PITPNC1,ARMCX2,YTHDC1,ELMSAN1,MFAP3L,TMEM130,DDX46,ALKBH8,SV2B,G3BP2,WDR20,GRIN3A,CASP8AP2,TOM1,EDN3,CNNM1,HEYL,ELN,C3orf18,TMEM35A,EPB41,KCNMB2,ZNF549,SPEG,CDKL3,MRPL10,RTN3,WAC,DLC1,FCGR1B,CEP78,CHST15,FKTN,FGF11,BAIAP2,TMEM164,AMOTL2,POLK,AGAP3,SEMA4D,FLT1,SLC37A3,FLYWCH1,NELFCD,EFCAB2,PDLIM5,CAMKK2,MEGF10,GABBR1,HRASLS5,GABRG2,HBS1L,ARPP21,DISC1,CPLX2,ALDH1L1,TUBGCP4,ADAM28,TTBK1,GLI2,GLUL,PCDH11X,ZNF638,GNG4,CCDC184,NUDT21,TMEM121B,RAPGEF4,RAPGEF1,GRIA4,CACFD1,GRM2,RNF165,AP4S1,RABL2A,GYG1,IRAK3,RASSF8,PADI2,NXPH3,NXPH2,HLF,HSF2,SHISA6,CELF5,FAAP20,KIAA1755,IL11RA,KCNN3,LMO2,FGFBP3,ZFYVE27,MAOB,PPM1L,MMP16,MOBP,MPP2,GIT1,JAKMIP3,MYO7A,NEK1,NEUROD1,VWA2,NOS1,PCBP3,NRCAM,NTRK3,SNTG1,PAK3,PCDHGC3,PCSK5,PDE4D,TMIE,CCSER2,SNX10,RETREG1,PKM,KCTD15,HMGCLL1,RC3H2,SDK2,PACSIN1,TNPO2,POLR2F,PPARA,PTPA,PPP3CA,NKAIN4,RANBP3L,PRKAB2,CEP41,MAPK8,MAPK10,DIRAS2,BCAS3,TMEM104,BDNF-AS,MTMR10,TMEM260,PTPRB,OCIAD1,PTPRE,PEX5,NKAIN1,RAB3A,PID1,USP47,RAP1GDS1,RASGRF2,RADX,HKR1,SLC6A15,ZMAT4,RET,RFX4,RGS3,RNF220,RPRD1A,GSTCD,ROBO2,CCDC102B,NEK11,TCP11L1,STK32B,LRRK2,ATAT1,DGLUCY,AMER2,FOXRED2,ATXN2,HOGA1,SCP2,MRAS,PPM1E,SLA,SLC1A3,FAM81A,LRRC55,ARHGEF40,ELMO2,SLC22A4,SMARCD3,RCOR3,KIF13A,CABCOCO1,SNRPN,KDM4B,SCN3B,SON,WDTC1,SOX2,TSNAXIP1,ZSWIM8,CLUAP1,ENKUR,EMC1,ZNF423,DBNDD2,RBM26,NFASC,TAB2,PBLD,POGZ,ITPRID2,GSE1,NSFL1C,ZFR2,VAMP1,VPS13A,TACR1,TAL1,ALG1,SMG6,WSCD1,ZEB1,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,PCDHB9,PUM2,FRYL,AHCYL2,ZFPM2,CRB1,LEFTY2,GALNT17,TIE1,TMEM9,ICAM5,DDHD1,ERCC6L2,HEY2,DAAM2,KCTD2,TPM1,CDK20,TPM4,RGMB,ZNF346,TRH,PDSS1,ZMYND8,TSN,TUB,SGK3,AMOT,LINC00689,VAV2,MEAF6,RBFOX3,WIPF1,GUSBP1,ZNF17,ZNF23,ZNF24,ZNF70,NDRG4,SLC26A10,TMEM237,EMSY,STMN4,LMAN2L,ADAMTS9,FAM47E,PDSS2,FZD3,TMEM63C,CASC15,FAM219B,ZNF248,MSRB3,LAS1L,PRRT4" MicroRNA hsa-miR-20a:mirSVR_highEffct hsa-miR-20a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.46E-153 8.23E-150 4.26E-152 3.93E-151 398 1684 "KCNH8,NCKAP5,SORCS1,SLC24A4,HACE1,ABCD2,ARHGAP20,MRTFA,SEMA7A,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,APP,SHTN1,AQP4,CASK,LINC00173,STK33,CAPRIN2,ASPH,RASL11B,ASTN1,ATP1A2,SLC4A4,EIF4G3,ATP1B3,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,RGS9,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,MAP7,USP6,P2RX6,C1orf52,TIGD7,CFL2,CHGA,CASC2,MS4A7,B4GALT6,TAOK2,EPS15L1,ZFYVE9,ABCG2,C4orf33,SLC25A27,AKAP5,SLC4A8,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,SIRPA,DNAL1,C8orf34,ZEB2,ZBTB24,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,RABGAP1L,OLIG1,USP3,CPEB2,DMTF1,DPYSL2,DRD1,DTNA,DNAJB6,DYRK1A,ABCC9,E2F5,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,FOXG1,SEMA4D,FLT1,EFCAB2,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,FYB1,GABBR1,GABRA1,TRAF3IP2,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,ADAM28,PPARGC1A,BRD8,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,ATP2B1-AS1,DIDO1,GRM7,CIT,LINC00839,TMEM25,AP4S1,RABL2A,IRAK3,HAS2,HPS5,KLF12,HTR5A,MSL1,ITGAV,JAK1,METTL21A,OLFM3,KCNJ10,KCNJ16,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,FGFBP3,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,SRSF12,KITLG,MID1,POC1B,XRRA1,MOG,MSR1,MXI1,MYCN,MYH6,NCF2,SFR1,NELL2,NF1,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,ETFRF1,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PLIN1,PRRX1,SPATA6,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,TMEM260,PTPN13,PTPRD,PTPRO,RAB5B,CEP97,TMEM255A,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,GTDC1,RFX4,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,ATXN2,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,IQSEC2,ZBTB43,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,NKAIN2,ERBIN,RGL1,ADHFE1,FAM168A,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,CAMSAP2,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,RALYL,FAM189A1,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,PRMT8,TTPA,UBC,UBE3A,UBTF,CCDC14,VLDLR,TBC1D15,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,CELF4,ZSCAN26,ANKS1B,LAMP5,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,RNF103,PCDH15,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-1275:mirSVR_lowEffct hsa-miR-1275:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-153 8.97E-150 4.62E-152 4.26E-151 416 1837 "VWA5B2,DGCR6,ASIC1,EMILIN3,GPRIN1,ADCY2,RNF157,PNMA8B,PLEKHH1,UNC5A,ADORA3,KLHL13,PCDH19,WDR35,PLA2G6,C1QTNF1,C1QTNF3,SEMA6A,UNC79,BEGAIN,DOC2A,AMPD2,AMPH,DPP10,LRCH2,CCDC146,USP28,CNIH2,PKP4,ANXA7,CNTNAP1,UPRT,APOC2,AQP6,SEMA4G,PDXK,ARHGAP5,ARHGDIA,ARRB2,MARCH3,ASPH,NCOA1,RASL11B,ATP2B3,ADGRB1,ADGRB2,SNAI3-AS1,BCHE,RGS11,HCN2,CFLAR,LDHD,CASTOR3,GYG2,CACNA1I,C5,GPC2,BSN,WASF1,CA4,CALB2,CABP7,KALRN,HAP1,NGB,BRSK2,PRC1,ZNF501,SHISA7,METTL6,SYNGR3,ENTPD2,LRRFIP1,LOC730101,MAGI1,JAM2,DLGAP3,NRXN2,TMEM59L,FADS2,QKI,HOMER3,PICK1,COL9A2,LETMD1,AKAP5,SLC4A8,MYRIP,PNKD,SEC31B,CREM,SH2B1,HINFP,CLIP3,NCAN,FAM169A,PITPNM3,SDC3,PLCXD3,CTNND1,GPSM1,MYADM,ARHGAP32,SNPH,GIT2,DBN1,DCT,DCTN1,HP1BP3,RUSC2,COPS7A,BLOC1S6,SGSM2,WDR20,CCDC3,DLG4,GRIN3A,DNAH9,TRAPPC9,DNM2,SLC12A6,DPH1,FAM57B,GNE,DTNA,ABCC5,AASDH,EBF1,SYT15,CNNM1,HEYL,SEMA3D,TMTC1,EFNA3,EFNB3,PHF20L1,SUGP2,ABI2,EGR3,RASA4,SORBS3,ELAVL2,CERCAM,ELAVL4,EIF1,EPB41L1,MTSS1L,EFS,EXTL1,MRVI1,EZH1,CLVS1,ZNF461,SCML2,ST3GAL6,KAT8,PPP1R1B,FGF11,BAIAP2,AMOTL2,SUCO,IP6K2,DCTN2,SORBS1,ARFGAP2,CAMKK2,ZNF605,CGREF1,TMEM151A,NRG3,GABRA2,RAPGEF6,ARPP21,SIGLEC8,SEPT9,MYOZ2,ALDH1L1,CYP46A1,GFRA1,ZNF276,TTBK1,TXNL4A,SPIN1,GLYR1,PCDH11X,AIFM3,STARD3,GNAO1,GNAS,GOLGB1,CNDP1,GPR12,STON1,STMN2,ATP2B1-AS1,GRIA1,GRIA4,PLCD4,GRIK1,ADAMTS13,GRIK5,GRIN2C,ATE1,KAT7,LINC01551,CELF3,PTGDR2,ATXN2L,KLF12,ARHGAP36,AGBL5,HNRNPK,FAAP20,IDH3B,C2orf72,IGF1,KNDC1,IGSF1,SCRT2,IL11RA,SLC6A17,INSM1,ZNF385B,KCNH2,KCNJ4,KHK,TTYH2,LIMS1,NCOA7,PIK3AP1,SYT9,LDLRAD3,MID1,GIT1,DBNL,STK32C,MYO6,MYO9A,FXYD6,NBL1,NCAM1,CCDC13,NEUROD2,NF1,NFIA,ALDH1L2,NFIX,NME4,VWA2,NUCB2,ZDHHC22,PAK3,PAX6,PBX1,PCSK5,PCSK2,CDK18,PDE4A,PDE1B,GNG2,PGAM2,GDAP1L1,PLCB2,FTO,SLC25A23,C11orf49,PRRX1,NECAB2,POLR2F,FSD1,PPP5C,VSTM2L,PRKAR1B,DIRAS2,VPS13C,SIDT1,DEF8,UHRF1BP1,TMEM260,CASTOR1,PTPRN,RIPOR1,NKAIN1,RAB3A,ACSS3,ZNF793,ATG16L1,IQSEC3,SUSD4,ZDHHC14,GAL3ST4,RGS3,RGS12,PRIMA1,SEC61A2,MYH14,CARF,PNMA8A,GLDN,SGSM1,PRR5L,YJEFN3,NCBP3,DGLUCY,AMER2,FOXRED2,MIR124-2HG,SBF1,ASIC4,PEAR1,TRIM46,FAM102A,ARX,FERMT1,MAGI3,PAAF1,WDR37,EPN2,SMTN,SLC6A7,SLC8A2,SLC8A1,SLC11A1,SLCO1A2,CPEB4,SMARCC2,CDK5RAP2,SNRPN,SOX2,SOX10,ZSWIM8,ENKUR,UHRF1BP1L,SPTB,TAB2,POGZ,NKAIN2,SSPO,ST5,NCDN,INKA2,MAPK8IP3,STAC2,KANK1,SULF2,SEPT3,RHBDL3,FNDC9,SYN1,SYN2,TACC1,CAMTA1,ANO4,ATMIN,WSCD1,DMXL2,TCF7,TCF7L2,SZT2,NAT16,FAM189A1,NSD1,TNS2,ARHGAP9,HIF3A,CYB561A3,RNF216P1,DICER1-AS1,THRA,TIE1,TMOD1,RIMBP2,KCTD2,CSMD1,KAT6B,ZNF346,TRPS1,NUTM2A,DCBLD1,TUB,SLC35A4,UBTF,GORASP1,FLRT1,PLEKHH2,VIPR2,VLDLR,TBC1D15,TSPAN11,CLIP2,NSD2,WNT7A,SLC13A3,SF1,TRIM9,ATP6V0E2,ZNF70,GPR158-AS1,CELF4,TMEM198,ZSCAN26,LAMP5,PLPPR5,PRDM2,NT5M,EVI5,LINC02210,ADAMTS9,SEMA3B,URM1,SLC17A7,ITM2C,MPPE1,EPM2A,AMN1,ADAMTS10" MicroRNA hsa-miR-4325:mirSVR_lowEffct hsa-miR-4325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-153 9.86E-150 5.06E-152 4.66E-151 368 1441 "CPNE2,SYN3,ACADM,CLK4,CSMD3,FMNL2,SLC12A5,ESYT2,PTCHD1,KIDINS220,MTUS1,SNX32,NR0B1,CC2D2A,ALAD,SMIM17,SEMA6A,ALCAM,BCAR3,PITPNM2,AMPD2,ANK2,PKP4,EPB41L5,ALS2,USP37,APP,AQP4,ARHGDIA,MARCH3,MARK4,ASPH,DACT3,NCOA1,ATP2B1,MTMR9,DPY19L3,RIPK1,KSR1,CDK5R1,DST,ST3GAL5,SYNJ2,MTMR2,C5,CACNA1B,CAMK2A,CAMK2B,CERS5,MTMR7,SEPT7,CDH18,CDO1,RCBTB2,SRSF11,NDST3,LHX2,RAB28,NMT2,DGCR9,FBXO7,QKI,CNGA3,AKAP5,SLC4A8,CPS1,C2CD2,HINFP,ANKRD44,CSF1R,SEC24C,ARHGEF10,CSNK1G3,VCAN,DZIP3,ERC2,UBXN2A,CTNND1,CTNND2,RIMS2,ECE2,HDAC9,ARHGAP32,ZFYVE16,EARS2,RASSF2,TOMM20,IP6K1,GIT2,ZEB2,ZBTB24,MAGI2,BLOC1S6,PLPPR4,SACS,SV2B,SPOCK3,RABGAP1L,DMD,DMTF1,DPP6,PDCD6IP,DTNA,ABCC5,DNM1L,E2F5,EDIL3,EDNRA,EDNRB,SGK2,HIPK3,KLHL5,TMTC1,APH1A,MBNL2,ABI2,RASA4,GOLGA7,EIF5,COPS4,STARD3NL,OLIG2,EPHA5,KCNMB2,ANKRD13B,CDHR1,TMEM74,RTN3,CHST15,STRADA,FGF13,FHL1,MEX3B,SYNCRIP,EVL,C2orf88,UFM1,MSANTD4,TBR1,STAG2,GALNT15,GALC,B4GALNT1,C15orf41,DISC1,TUBGCP4,GFER,PPARGC1A,KIRREL3,COPS8,HPGDS,DBF4,SPIN1,PCDH11X,GNAS,GNG4,FERMT2,PRUNE2,GPR34,EML4,GPR37,GRIA4,GRM7,RNFT2,GUCY1B1,HAS2,ZHX1,PTGDR2,HMGB1,SCRG1,GABARAPL2,SYNPO,TLX1,HSF2,IGF1,C5orf24,LIX1,ZNF678,ITGAV,JAK2,KCNA4,KCNK2,KCNN2,KIF5C,TTYH2,LAMP2,INSYN2,SFXN5,VWA5A,NCOA7,LOC100128239,MAN2A2,MAP2,MARK3,MATN2,MATN3,MBP,TM6SF1,LRP1B,MEF2C,MEIS1,AFF1,MOG,COMMD5,SESN3,FXYD6,NAP1L3,NCAM2,NEUROD2,ALDH1L2,NFIX,NODAL,NOVA1,NPTX1,SLC11A2,IGSF11,OLR1,OPHN1,OPRL1,PBX1,PCSK2,PDE4D,PIRT,PFKFB2,XRN1,NLE1,EPB41L4B,PPP2R2C,PRKCB,MAPK9,MAPK10,SIDT1,PSMD13,CNTLN,ELOVL2,PTPRO,FAM120C,TUG1,PPP2R3C,ARID4A,ZYG11B,REV3L,RGS4,TTLL7,RIC8B,PBRM1,RAVER2,ROBO1,ROBO2,ZC3H14,SGSM1,ACER3,TCP11L1,SOX8,RYR3,FAM182A,RMI1,FOXRED2,SATB1,ATXN1,ATXN2,LINC00461,SCP2,FOXRED1,HSPA4L,ITSN1,SH3GL2,PPM1E,NTNG1,SHC4,FNDC3A,SLITRK3,SLC1A3,FAM81A,URGCP,BTBD3,DHX30,SLC6A8,SLC8A1,CCDC88A,TRIM67,CPEB4,COA1,SMARCE1,RCOR3,INAVA,LIMCH1,PALLD,PDZRN3,UNC80,SON,SOX11,ZSWIM8,SP4,CLUAP1,EMC1,IDI2-AS1,ZNF423,KIF1B,ZNF302,SAMSN1,LRRC4,RGL1,ADHFE1,PHLDB1,KANK1,FAM168A,SYT11,FGD4,PLCB1,C12orf76,CAMTA1,DNMBP,UNC5D,TBL1X,VWA3A,DMXL2,USP22,CLASP1,RALYL,PCDHB7,PCDHB6,FRYL,PMS2CL,C18orf54,ITGB3BP,LEFTY2,TGFBR3,SLC44A1,TIAM1,TJP1,DAAM2,R3HDM1,TNS1,TPM1,CDK20,NPL,METTL3,PRMT8,ANO5,RFTN2,HIRA,CADM1,FAM155A,USP1,MEAF6,VLDLR,GUSBP1,ZNF28,TRIM9,LYPD6,ZBTB38,ZNF189,CADM2,PRDM2,RNF103,TMEM178A,HRASLS,GOPC,AMN1,UBE3B,KAT6A,HNRNPA3,CASC15,RNF170,MSRB3,FXR1,FRMD6" MicroRNA hsa-miR-96*:mirSVR_lowEffct hsa-miR-96*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.67E-153 1.50E-149 7.66E-152 7.05E-151 408 1771 "RALGAPA1,KCNH8,CLK4,ABHD6,NCKAP5,FMNL2,SLITRK1,ADD1,ADD3,RNF150,GPR158,HECW2,HACE1,ALCAM,SRPX,PCDH10,BBOX1,TRMT9B,ZFAT,PHF12,PPFIA2,APC,DGKD,ALS2,SHTN1,ARNTL,MARCH3,PCDHGB4,NUMB,ASTN1,ZNF582,DPY19L3,MIR9-3HG,LDHD,FUBP1,NIPA1,MYRF,BTRC,CACNA1A,CACNA1B,CACNA1D,CACNB4,CABP7,CALM1,KALRN,VSTM2A,RUNX1T1,USP6,INA,SLC16A4,TMEM257,CD38,C1orf52,REPS2,CDH2,DCLK1,LGI1,SOCS6,CHM,ZBED5,KMT2C,NMT2,SULT4A1,CNN3,IQCK,AKAP6,SLC4A7,TOGARAM2,MYRIP,ZFP28,MFSD4A,CHD1L,CRHBP,ANKRD44,TRIM69,SNCAIP,CSF1,CSF2RA,ATRNL1,IPCEF1,SIPA1L1,VCAN,CNTNAP2,PLXNA4,GREB1,RUBCN,USP6NL,EDRF1,KIAA0408,TCAF1,FRMPD4,HDAC4,RIMS3,MAML1,TMEM170A,DAPK1,AIF1L,ARMCX2,MYEF2,CNIH3,TMEM130,DDX46,SV2B,WDR20,DRP2,GNE,ECM2,KRBA2,GOLT1B,ST8SIA3,HIPK3,SEMA3D,FSD1L,RBM12,PHF20L1,MBNL2,RASA4,KCTD3,EIF4G1,COPS4,RGS17,PCOLCE2,TMEM35A,PAN3,EPHB1,STX2,ERBB2,DENND4A,NRN1,F5,WAC,RPS6KC1,ZIC4,TAOK3,DLC1,ATP8A1,CEP78,KAT8,SEC24B,KIAA1109,FGF13,PRKAG2,SCARA3,FOXG1,CAP2,RGPD5,ZMYND15,EVL,UFM1,DACH2,TBR1,AP4B1,STAG2,MEGF10,GABRA1,GABRA5,DENND2A,BRPF3,B4GALNT1,ZNF234,ERAP1,TUBGCP4,PPARGC1A,SPIN1,STARD3,ZNF638,PRUNE2,PCLO,STMN2,GRIA1,GRIA2,GRID1,ADAMTS13,GRM1,RNF165,FAM107A,WIF1,MUM1,C1orf94,NXPH2,KLF12,TNFAIP8L3,HNMT,ZDHHC15,HTR5A,IRF8,C5orf24,HES5,IL11RA,BRINP3,KCNA1,KCND2,KCNJ3,KLHL23,KLC1,KPNA5,LIFR,SYTL4,VWA5A,HECTD2,ARHGAP12,GPR155,MAP4,MAP6,MAT2A,MBP,SYT9,CHIC1,LDLRAD3,TM6SF1,MIA2,ERICH3,MRPL42,MYO5A,NCAM1,NEFM,NEK1,NEUROD1,NF1,NRCAM,HCN1,NTRK2,IGSF11,OXTR,GPR137C,KCNK10,GLIPR1L2,PAK3,PCDHGC3,PDE2A,PDE4B,TMOD2,CYTL1,PFKFB3,GDAP1L1,PIK3R1,ZNF655,PMP2,MAPKAP1,STRN3,LRP12,ING3,SPATA6,FAT3,POU3F2,DRAM2,CRLS1,PPP3CB,RANBP3L,VSTM2L,EPDR1,GDPD1,VPS13C,LRRC49,APTX,QRICH1,PTCH1,PTK2,ZSCAN32,PEX5,ACSM5,TUG1,CEP97,USP47,ZCWPW1,DBX2,KHDRBS2,GTDC1,RGS4,RGS10,TTLL7,MRPS18A,KLHL11,SEC61A2,RNF220,RIC8B,RNASEL,ZNF532,ROBO2,MRAP2,ATP8B4,ACER3,KCNIP1,RTN1,NCBP3,AMER2,LRFN5,SELL,CASC3,FOXRED1,SH3GL3,NTNG1,CHD9,FHOD3,SYBU,SLA,PREX2,SMTN,WDR47,RAB3GAP1,CCDC88A,NAPB,BTBD7,CPEB4,SLN,SMARCA4,MYH15,ANKRD36,PDZRN3,MYO16,UNC80,DOP1A,ZSWIM8,SP4,EMC1,HECW1,TEX2,ZBTB43,SPART,ZC4H2,ERBIN,ZSCAN29,KANK1,KLHL7,NECAB1,FGD4,JMJD6,ADAMTS17,SYP,TACC1,MTCL1,PJA1,MCF2L,IQCE,KLHL4,ANO4,VWA3A,TCF4,DMXL2,ZFP90,TCF7,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,PCDHB6,AKNA,USP32P1,ATP13A2,DICER1,ZFPM2,ITGB3BP,AP4E1,ZNF106,SLC44A1,C9orf85,TPM4,DOK6,NR2C2,SYNPO2,TRIO,TRPC3,CADM1,RPL7L1,UBE2H,UGT8,PITPNB,PLEKHH2,TBC1D15,WIPF1,NSD2,WRN,PCDH20,ZBTB14,ZNF24,KCNT2,TRIM9,PLPP4,ZBTB38,SLC30A4,SLC38A1,EVI5,STOX2,RNF103,PCDH15,FAM13C,FZD3,SMIM8,ADAMTSL3,ZNF248,RNF170,SOCS4,ST8SIA2,SLC4A10,GAN,FAM198A" MicroRNA hsa-miR-519a:mirSVR_lowEffct hsa-miR-519a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.15E-153 1.77E-149 8.98E-152 8.27E-151 402 1721 "SYS1,ACTN2,SLC25A25,GALNT16,CCDC85A,ADD1,SORCS1,USP31,RNF150,PTCHD1,ADRA1B,BEND6,HECW2,WDR35,AK2,SPOP,CDC42BPA,CCDC146,MYH7B,PHF12,EPB41L5,GPAM,TNRC6C,MIER1,CDK10,ARHGAP5,PLA2G4C,MARCH3,NCOA1,NUMB,DDX3Y,INSYN2B,DPY19L3,ADGRB3,RGS11,BCL2L2,BCL7A,FUBP1,MTMR2,SGCE,NIPA1,OSGIN2,BTRC,CACNA1E,CACNB4,CALM1,KALRN,NGB,CAMK2D,CAMK2G,SYT6,CBFA2T2,C1orf52,REPS2,CDC27,LGI1,NOG,CASC2,MS4A7,SYNPR,B4GALT6,KMT2C,EPS15L1,CLCN4,CLTC,QKI,CNR1,IQCK,PCYT1B,SLC4A7,IFFO1,ZFP28,CNRIP1,MFSD4A,PNKD,CREB5,HAPLN1,TRIM69,FEZ2,ATRNL1,PDE4DIP,CNTNAP2,FAM169A,APPL1,ST18,RUBCN,MYADM,GAPVD1,FRMPD4,ZNF337,DGKB,DGKG,DNAL1,SPATA2,C8orf34,ZEB2,MFAP3L,HP1BP3,CEP170,MAGI2,ZC3H11A,GUCD1,RHOBTB1,SNAP91,SRGAP3,G3BP2,DLG2,HS3ST4,HS3ST2,DMTF1,SLC25A18,DRD1,ACOT8,ABI1,DTNA,ABCC5,E2F5,SNX29,WDPCP,EDN1,EDN3,HIPK3,TMTC1,SUGP2,GOLGA7,ELAVL2,BSCL2,PAN3,EMX2,EPB41L1,EPHA5,ANKRD13B,EPS8,ERBB4,MRPL37,TLR7,KATNAL1,WAC,ST3GAL6,MED12L,CAMSAP1,POLK,SEC23B,PCYOX1,SYNCRIP,ATP13A4,ANKFY1,SGIP1,NOP56,TACC2,NPTN,CELF1,GABRB1,GAD1,HBS1L,ZMYND11,ZNF274,GAP43,GART,DNER,TUBGCP4,ARFIP1,AHDC1,MALT1,RUNDC3A,TNRC6A,MSL3,CBX1,INSM2,GPT2,ADGRA3,GPD2,GPM6A,DIPK1C,GPR34,NUDT21,PCLO,RAPGEF1,GRIA1,NR3C1,ZNF496,MFSD2A,SOX21,GUCY1A1,WIF1,IRAK3,GPR45,PTGDR2,HNF4G,DHX35,SHISA6,CELF5,SMAP1,IGF1,IL11RA,INPP5B,SLC35G1,KCNA1,KCNA6,KCNC2,KIT,LAMP2,CAMK2N2,SFXN5,LMO2,ZNF667-AS1,MAP2,MAP6,LDLRAD3,SCAMP5,AFF1,PTOV1,NRBP2,TAGLN3,MTR,MXI1,LYRM9,MYH6,MYO9A,NAP1L1,NAP1L2,P2RY13,NBL1,NCF2,NDUFA5,SFR1,NFIA,NFIX,NHLH1,NPTX2,NTRK2,NUCB2,OPRL1,KCNK10,PAX6,PBX1,PDE4D,PDE1B,TMOD2,PFKFB2,PFKFB3,PFKP,CDK14,DUSP26,SSH1,PIK3CD,XRN1,GPSM2,SLC25A23,LRP12,PRRX1,SDK2,ING3,MINDY2,CCDC144B,PRKCZ,MAPK3,MAPK4,DEF8,MDGA2,MTMR10,OCIAD1,PTPRD,PTPRE,FAM184A,RBBP8,RADX,BSDC1,REV3L,GTDC1,PRIMA1,RPRD1A,LGI2,ROBO2,ELP2,TMEM100,NEK11,FBXW7,ZC3H14,GLDN,RPS20,CLIP1,ZNF331,FAM182A,AMER2,SATB1,ATXN1,SCN2B,TNFRSF19,PEAR1,TRIM46,PUF60,MAGI3,FBXO11,NUBPL,CLSTN1,WDR37,BTBD3,SMTN,WDR47,SLC6A8,KDM4D,SLC8A1,SLC11A1,SHANK2,SLC12A2,NAPB,SLC15A2,TET1,CPEB4,ZNF667,SORCS3,TTC17,RIMS1,SNAP25,SNCA,MBD5,PDZD2,TNIK,KIF21B,FNBP1,SP4,UHRF1BP1L,KDM4C,IDI2-AS1,ZBTB43,TSPYL2,RBM26,NFASC,SRPK2,EPB41L3,SEPT8,DIP2A,AJAP1,MLC1,SYN2,ATP11A,TACC1,MTCL1,EXOC7,UNC5D,TMEM136,ATMIN,TCF4,CUX2,ZEB1,AZIN2,SYNE1,NAT16,PHF24,HIF3A,TEK,DICER1,CRB1,ITGB3BP,AP4E1,TIAM1,ZFP91,TMPO,RIMBP2,RGMB,SMUG1,RUNDC3B,TRPS1,TUB,PRR18,RPRM,LINC00689,OSBP2,TOM1L2,CCDC14,WIPF1,CLDND1,MICU3,KCNT2,LYPD6,ZBTB38,SYNC,EMSY,PRDM2,SLC38A1,EVI5,STOX2,PRDM8,PCDH15,NAV2,SLC17A7,C12orf4,GOPC,FAM13C,FZD3,ST7,UBE3B,PAK5,FBXO36,FAM219B,NLRP3,TTC7A,SLC39A12,ST8SIA2,FAM198A,JPH3" MicroRNA hsa-miR-138-1*:mirSVR_lowEffct hsa-miR-138-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.83E-153 3.27E-149 1.65E-151 1.52E-150 391 1632 "AS3MT,CSMD3,ADCY2,CCDC85A,TMCC3,SLC12A5,RNF150,PTCHD1,KIDINS220,SLC44A5,INTS2,GPR158,HECW2,KCTD16,HACE1,CC2D2A,HFM1,TAOK1,ALAD,ALK,AMPH,OGT,CCDC146,USP28,PHF12,APBB2,DGKZ,UPRT,CPNE5,MIER1,CASK,TMEFF1,ASPH,ZBTB10,NCOA1,NUMB,ASTN1,ATP2B3,B3GALT2,ATP6V1G2,DOCK11,SNAI3-AS1,CFLAR,SYNJ1,ARHGEF7,FUBP1,NAE1,BTK,NIPA1,CA8,CACNB4,CALB2,CAMK2D,VSTM2A,SCARB1,CD38,C1orf52,CDO1,CCPG1,NOG,CHGB,SYNPR,CNOT8,JAM2,KMT2C,TJP2,QKI,CNN3,CNR1,AKAP7,ARMC8,SLC4A8,RCHY1,CNRIP1,AKAP12,GDA,FEZ2,CSNK1E,SIPA1L1,FAM169A,ERC2,GREB1,PUM1,DCAF4,CYBB,HDAC9,FRMPD4,KIAA0513,ZFYVE16,DGKB,TMEM170A,IP6K1,PABPC5,DBI,ARMCX4,C8orf34,MYEF2,KIAA0319,ALKBH8,RHOBTB1,SACS,SV2B,CDON,DMTF1,PDCD6IP,MAMLD1,FARSB,E2F6,EFNB3,MBNL2,EGR3,COPS4,RGS17,STARD3NL,C8orf37,EPB41L1,RCAN2,EPS8,ERBB4,ERCC2,DENND4A,RRAGB,ADGRV1,EYA1,MRVI1,WAC,SCML2,CEP78,TOMM40L,ACTL6B,UBE2E3,MEX3B,TMEM107,ATP6V1H,ATP2C1,ZNF605,ERGIC3,CELF1,FYB1,GABRA1,GABRG2,GAD1,GAD2,GALC,ZNF234,NEK6,DISC1,WASF3,KIAA1841,MYOZ2,IGSF5,PCDH17,LYVE1,TTBK1,CRCP,TCERG1,DBF4,RAB30,GLRB,FERMT2,GPM6B,ATF7,TDRKH,GPR12,STON1,GPR34,GPR37,RAPGEF4,GRIA1,NR3C1,GRM7,BTN2A1,GUCY1A1,GUCY1B1,IRAK3,HAS2,UBE2QL1,HPS5,TOX2,C1orf94,NXPH2,ARHGAP36,SCRG1,HMGCL,HNMT,HSF2,LINC00667,ZIC5,RBPJ,LRRCC1,PLD5,LIX1,IL6ST,ZNF678,ITPKB,JAK2,KCNA4,KCND1,KCNK1,KCNMA1,KCNN3,L1CAM,LAMP2,STMN1,INSYN2,PAXBP1,VWA5A,ARHGAP12,PIK3AP1,MARK3,ADAM11,MEIS1,KCTD6,AFF1,WDR49,MOBP,CD200,ERICH3,COL28A1,SAMD5,MSRA,NRBP2,N6AMT1,MTTP,MYO6,MYO9A,MYT1,NAP1L2,NAP1L3,NELL2,NF1,CNOT4,NPTX2,NTRK2,NUCB2,CHAMP1,OMG,PCDH9,PFKFB2,CAMKV,PIK3C2A,NOMO2,ANLN,PIK3R1,PLCL1,MED1,CRLS1,KANSL1,RASGEF1B,MAPK9,DCHS2,SAMD9,WBP1L,MDGA2,CNTLN,PTCH1,ELOVL2,PTPN13,OCIAD1,PTPRG,FAM120C,PTPRZ1,PEX5,TUG1,ZNF793,NWD1,RAP1GDS1,ZCWPW1,OXR1,RBBP6,SLC6A15,RET,GTDC1,FIGN,RGS4,RGS7,RGS12,CARF,ROBO1,CCDC25,ELP2,CCDC102B,TMEM100,NEK11,MCMBP,GLDN,ACER3,LRRK2,ABCA11P,ZNF568,FAM182A,SEMA6D,ATXN2,SCN7A,TNFRSF19,ZFP2,TRA2B,PPM1E,ARX,FNDC3A,SEC31A,WDR37,BTBD3,SLC9A5,SLC12A2,SMARCC2,OGDHL,CDK5RAP2,ANKRD36,RIMS1,FAIM2,LMBRD1,PALLD,UNC80,BDP1,NMNAT2,CLUAP1,UNC5B,CDK19,MCF2L2,TAB2,ITPRID2,SAMSN1,NXT2,INKA2,ELOVL4,DIP2A,SYT11,ARHGEF9,FNDC9,SYP,SYPL1,C12orf76,POPDC3,ATP11A,TACC1,EXOC7,DNMBP,TAL1,UNC5D,ADGRL3,VWA3A,ZEB1,TRIM2,WDR7,PCDHGA11,PCDHB9,TEK,ZFPM2,AP4E1,MTMR14,TNR,PIK3R5,TPM2,STXBP4,TRPS1,TSN,TTPA,CADM1,EIF4ENIF1,GORASP1,SLAIN1,FLRT2,LAT2,NSD2,PORCN,GUSBP1,XPO1,XRCC4,ZIC1,ZNF23,CFAP52,ZNF540,ZBTB38,ZSCAN26,ANKS1B,CADM2,PRDM2,RGMA,RNF103,PCDH15,WNK3,SLC17A6,PARP11,RGS7BP,DNAH10,FAM219B,ADAMTSL3,ZDHHC20,SOCS4,FAM198A" MicroRNA hsa-miR-200b*:mirSVR_lowEffct hsa-miR-200b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.22E-153 3.49E-149 1.76E-151 1.62E-150 404 1741 "VWA5B2,CLK4,CSMD2,ARID1A,CSMD3,KLRC4,RNF157,CDC7,SORCS1,PWWP2A,BEND6,SLC44A5,INTS2,HECW2,AK2,SEMA6A,ALCAM,SRPX,PCDH10,AMPH,ZFAT,ANK3,CCDC146,PPFIA1,PARG,APC,DGKZ,AQP4,PPP4R4,CASK,TMEFF1,ARHGAP5,ARNTL,ASCL1,ASPH,PCDHGB4,NUMB,INSYN2B,ATM,RNF182,ATP6V1G2,ADGRB3,BCL2L2,NRP2,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,MTMR3,C5,RAB29,CACNB2,PTBP2,RUNX1T1,TMEM257,CD38,DCLK1,LRRFIP1,MAGI1,CCPG1,NUMBL,NDST3,PLAA,CLCN4,C4orf33,ARMC8,FAM149A,COL4A5,SUMF2,TOGARAM2,ZNF521,CPS1,CLOCK,RBM39,SLC32A1,ANKRD44,GDA,TRIM69,CS,SNCAIP,LRRC3B,CSNK1G3,SIPA1L1,VCAN,APPL1,PNPLA8,PUM1,CCDC144A,TMEM170A,BRINP1,DNAL1,MFAP3L,CEP170,MAGI2,KLHL3,BLOC1S6,SV2B,SPOCK3,KBTBD11,CHRDL1,DLG2,DLG3,DMD,USP3,ATN1,DTNA,EDNRB,ATL1,FCF1,KLHL5,FSD1L,YAF2,PHF20L1,SUGP2,ABI2,PLEKHA1,EML1,TUBD1,MTSS1L,ANKRD13B,EPS8,DENND4A,ABCA8,ACSL4,EFEMP1,ATP8A1,CEP78,PRMT5,FER,FGF1,FGF12,IP6K2,SYNCRIP,IQCG,SEMA4D,FLT1,SLC37A3,TMEM107,PDLIM5,ATP2C1,CELF1,NSG1,MEGF10,GAB1,GAD1,AHCYL1,ZMYND11,SIGLEC8,C15orf41,DNER,GATM,FAXC,TUBGCP4,SESN1,FREM1,PCDH17,PPARGC1A,GK,TCERG1,SPIN1,TOX3,PCDH11X,MAP7D2,GPM6A,GPM6B,PRLHR,GRB10,GRIA1,GRIA2,DIDO1,RFFL,GRIK2,GRM1,GRM7,KIF3A,BVES,AP4S1,PSIP1,GUCY1B1,RASSF8,HAS2,HNRNPK,ZDHHC15,NEGR1,SMAP1,HTR2A,IRF8,MSL1,ZIC5,IL6ST,ZNF385B,JAK2,SLC35G1,METTL21A,KCNC2,KCNN2,LAMP2,LIMS1,PAXBP1,SYTL4,ARHGAP12,CLEC18A,LOC100128239,MAN2A2,MAPT,SYT9,TM6SF1,SHC3,SESN3,CCDC80,MSI1,ADAM22,MTTP,MXI1,MYO9A,RTL5,NELL1,NF1,NFIA,GPR137C,CNTN3,PAX6,PCDHGC3,PCDH8,PCDH9,PDE3B,PDE4B,PDGFRA,CYTL1,FAM98B,HERC2P3,ANLN,ZFYVE21,XRN1,FAM216A,JAKMIP1,FTO,HMGCLL1,PURG,PRIMPOL,PMP22,STRN3,LRP12,SCHIP1,PPARA,MINDY2,TATDN3,PPP2R2C,PRKACB,KLK6,VPS13C,WBP1L,SYTL2,GON4L,SNRK,CNTLN,ANKHD1,UHRF1BP1,ZIK1,PTPRE,ZNF615,FAT4,ARID4A,DBX2,KHDRBS2,TRIM68,RIC8B,ZFHX4,CCDC82,EXD2,RAVER2,RPL15,BAALC,GLDN,SGSM1,STK32B,KCNIP2,CLIP1,FAM182A,TRAPPC13,DGLUCY,SEMA6D,SATB1,ATXN7,LINC00461,PRCD,SCP2,TNFRSF19,ELMOD1,IL17RB,SOX6,CASC3,FOXRED1,SFPQ,NLGN4Y,ZFP30,KIF21A,PPM1E,ARX,NTNG1,R3HDM2,SLITRK3,NLGN1,SLC1A3,LRRC55,RADIL,RAB3GAP1,CCDC88A,TMEM132D,ELMO2,SLCO1A2,SLIT1,COA1,ANKRD36,SNAP25,FAM126B,PDZRN3,MYT1L,KIF21B,FNBP1,SOX11,NMNAT2,COLGALT2,SAMSN1,ELOVL4,CEP68,SEPT3,SYNE2,NUDT10,PLCB1,SYPL1,SYT1,COBL,TAF9,TAL1,TBCEL,EHBP1,SIN3B,SATB2,ZEB1,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,RALYL,SLC19A3,USP32P1,TF,FAM200B,C18orf54,AKTIP,TLL2,ERCC6L2,NPL,RGMB,SYNPO2,TRPC1,TRPC3,FNDC5,ANKRD20A2,TMEFF2,CADM1,UCHL1,SLAIN1,FLRT2,FLRT1,MEAF6,CCDC14,VLDLR,RBFOX3,ZNF711,LYPD6,ZNF154,TMEM237,ANKS1B,WNK1,CADM2,TMEM178A,PCDH15,FIP1L1,GOPC,DNAH10,FAM13C,SMIM8,CERS6,SSPN,CBLN2,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-508-5p:mirSVR_lowEffct hsa-miR-508-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.99E-153 3.92E-149 1.96E-151 1.81E-150 419 1870 "SYN3,ACADM,ACLY,ADCY6,TMCC3,ADD2,ADORA1,BEND6,INTS2,GPR158,HECW2,TBC1D14,GOLGA7B,AMPD2,AMT,OGT,EP400,PI16,CCDC146,NT5C3B,BCAS1,CDC14B,SFMBT2,IGDCC4,ZFYVE28,ALDH4A1,ATM,CADM3,DPY19L3,ATP6V0A1,DOCK11,ADAM15,BACH1,LINC00847,BCL7A,KSR1,DST,CASTOR3,CACNA1G,MMD2,DDR1,CACNB2,LURAP1,KALRN,PTBP2,CAMK2G,SYT6,HIP1R,NFS1,ZNF501,KRIT1,USP2,P2RX6,ARHGEF2,CDC42,CDH8,ZMYM4,CDO1,RCBTB2,FOXN3,MAP4K4,NIPBL,COL9A1,BTF3L4,COL9A2,SLC4A7,SLC4A8,ABI3BP,IFFO1,SMARCAL1,MYRIP,CP,CHD1L,C2CD2,HAPLN1,RNF14,ATRNL1,GALNT9,VAC14-AS1,FAM169A,CTNND1,DCAF4,EDRF1,BOC,ARHGAP32,MAML1,DAPK1,YTHDC1,DGCR5,MYEF2,HP1BP3,KIAA0319,CEP170,SNAP91,SACS,SPOCK3,RABGAP1L,ARNT2,ZNF582-AS1,CHRDL1,CDON,DMTF1,DPH1,DRP2,DTNA,DYRK1A,DNM1L,USH1C,FAM135B,EDN3,PHC2,SGK2,CNNM1,HEYL,RBM12,PHF20L1,MRO,ABI2,RASA4,GOLGA7,DCTN4,RCAN2,EPHB1,STX2,RCSD1,RRAGB,ADGRV1,F3,FAM198B,TUBB3,SCML2,EFEMP1,DLC1,ZNF589,PCYOX1,SEMA4D,FLT1,SLC37A3,NELFCD,NBEA,SMC2,UFM1,ARFGAP2,CAMKK2,ZNF605,PRELID3A,KHDRBS3,NSG2,DACH2,DLL3,SARAF,TVP23A,SDCBP2,GABRA1,BRPF3,RAPGEF6,IP6K3,C15orf41,ATP8A2,NEU3,TUBGCP4,GFAP,CSDC2,PPARGC1A,GJB1,DHRS4,GLUL,KDM2B,INSM2,LUZP2,KCNMB4,GNAS,GPD2,LILRA1,CECR2,RAPGEF4,GRB10,RAPGEF1,DIDO1,SERP2,PRDM5,GRM7,RNF165,BVES,AP4S1,SOX21,LINGO1,SLC2A6,MAEL,MAN1B1,HMGB1,HMGCL,HNMT,CELF5,ATCAY,FAM95B1,C5orf24,IGSF1,IL6ST,IL11RA,SLC35G1,KCND1,KCND2,KLHL23,KCNK2,KCNMA1,KCNQ2,CREG2,KIF5C,KIT,KPNA5,IPO5,TTYH2,INSYN2,LIFR,SYTL4,NCOA7,MATN3,SYT9,MEIS2,KITLG,MOBP,GIT1,MSI1,JAKMIP3,MSRA,NRBP2,DDX25,MYO6,NCAM1,RCOR2,NFE2L2,NME4,NODAL,NOVA2,SLC11A2,NTRK2,NUCB2,IGSF11,ZNF713,ETFRF1,PDCD2,PDE3B,PDGFRA,PENK,CYTL1,PFKFB4,ZNF655,CCSER2,GPSM2,JAKMIP1,FTO,SLC25A23,CDIP1,STRN3,EPB41L4B,POU3F2,FSD1,POU6F1,MINDY2,PTPA,MAPK3,HYDIN,SAMD9,WBP1L,SIDT1,PSMD13,PTPN13,PTPRB,PTPRH,C1orf109,PEX5,PYGM,RAD52,FAM66C,NWD1,OXR1,RASGRF2,ZYG11B,DPF2,FIGN,RGS3,RGS4,PBRM1,RNASEL,PCMTD2,SPIN3,PAQR6,MEG3,ABCA11P,ST6GALNAC6,KCNIP3,YJEFN3,RTN1,ZNF568,RYR3,DRAXIN,ATXN2,HES6,ZFP2,FOXRED1,RASA3,HSPA4L,KIF21A,ITSN1,CPEB3,DOCK10,MAGI3,AMBRA1,BCAN,NLGN1,DZIP1,PAAF1,WDR37,ZNF365,SLC1A3,BTBD3,WDR47,RAB3GAP1,ARHGEF40,SLC9A5,SLC12A2,SLC12A4,SLC15A2,ARFGAP1,ZKSCAN3,SMARCA4,RCOR3,MAPKBP1,MBD5,LMBRD1,FAM126B,PDZD2,WDTC1,SOX2,TNIK,CLUAP1,GLT8D1,ZNF423,NPAS3,ITPRID2,ZNF302,SAMSN1,ZC4H2,SSPO,SEPT8,TTBK2,RGL1,ADHFE1,STX1A,KANK1,SULF2,ARHGEF9,VPS13A,FNDC9,SYP,CAMTA1,MLST8,UNC5D,ADGRL3,FBXW11,TMEM136,TCF7L2,TPCN2,TCF12,USP22,WDR7,SYNE1,SLC19A3,NSD1,PCDHA5,AHCYL2,DICER1-AS1,ZNF106,TIAM1,RELL2,C5orf64,KAT6B,PIK3R5,RBFOX2,SEZ6L,DOK6,SMUG1,NEIL2,FNDC5,PITPNB,USP1,VLDLR,CLDND1,RICTOR,LGI4,SLC47A2,ZIC3,ZNF24,ATP6V0E2,ZNF138,ZNF184,ZNF189,ANKS1B,ZXDA,CADM2,LINC02210,PRDM8,SCG2,PCDH15,NAV3,URM1,PPP1R3F,KCNAB1,PLSCR4,EPM2A,DOCK8,PHTF2,ACTR3B,JMJD1C,TRAM2-AS1,SSPN,FRMD6,SPATA13" MicroRNA hsa-let-7a:mirSVR_lowEffct hsa-let-7a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.70E-153 4.33E-149 2.15E-151 1.98E-150 410 1793 "GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,ANK1,ANK3,LCORL,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,SHROOM2,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,CHID1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM23,ADAM15,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,TIGD7,CLGN,ASIC3,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,CNGA3,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,TRIM69,ABCG1,CS,RGS6,SEC24C,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,DCT,ZBTB24,MYEF2,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,GRIN3A,DOCK2,DMTF1,DPH1,PDCD6IP,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,SNX29,EDNRB,ANKRD46,RBM12,YAF2,EBI3,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,NCALD,CDHR1,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,CHST15,TOMM40L,GTF2IRD2,CAP2,IP6K2,HVCN1,UFM1,FAM49B,USP21,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,GABRG1,ZNF234,SIGLEC8,DISC1,ATP8A2,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,OPALIN,CELF5,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,KIF5C,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,PABPC1L2A,NDUFA5,NEFM,NELL1,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,OXTR,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PLCB2,PLP1,HMGCLL1,C11orf49,TRHDE,SCHIP1,RANBP3L,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,UHRF1BP1,TMEM260,PTPRD,PTPRG,FAM120C,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,TRIM68,KCTD17,RIT2,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,EPHA10,SPIN3,KIAA0895L,ACER3,TCP11L1,PTGR2,RTKN,TRAPPC13,ATXN2,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,FOXRED1,HSPA4L,ITSN1,CPEB3,ST6GAL1,CTXN2,WDR37,SLC1A7,BTBD3,RUFY2,FAM214B,SLC6A1,SLC6A8,KDM4D,SLC8A2,ATF7IP,SLCO1A2,CPEB4,MAST1,SMARCD3,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,NFASC,TAB2,POGZ,ITPRID2,STOX1,SSTR2,SYT11,MLC1,FGD4,FNDC9,PLCB1,SLC37A2,TAC1,PDLIM2,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,HIF3A,RNF216P1,DICER1-AS1,AP4E1,FBXL16,ARL10,ERCC6L2,DAAM2,KCTD2,TNFRSF1B,C5orf64,NPL,CHST5,SMUG1,TRIO,STXBP4,TRPC3,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF28,ZBTB16,MEIS3,WNK1,CSDE1,FIP1L1,TRIM16L,UBE3B,KAT6A,CASC15,NUP214,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-127-5p:mirSVR_lowEffct hsa-miR-127-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.51E-153 4.78E-149 2.37E-151 2.18E-150 416 1845 "RALGAPA1,TTYH1,SERPINA3,ASIC2,NCKAP5,ACTN2,KDM5D,GPRIN1,DSCAML1,GALNT13,ERMN,UNC5A,KIAA1211,SNX30,ESYT2,KIDINS220,SLC24A4,INTS2,HECW2,KLHL13,WDR35,TXNDC16,PLA2G6,SPOP,ALCAM,BCAR3,GOLGA7B,AMPD2,ZFAT,PPFIA1,APC,UPRT,TNRC6C,PPFIA3,PPP4R4,RGS20,CDK13,NUMB,TMEM108,SLC4A4,CADM3,RIPK1,ADAM15,BACH1,ADGRB3,MPDZ,BCL2L2,GPR146,KSR1,DST,SYNJ2,ARHGEF7,FUBP1,CASTOR3,MYRF,BAIAP3,CA4,CACNA1A,SLC25A14,CAST,SPAG9,NFS1,ARHGEF25,SEPT7,REPS2,CDH2,LARGE1,IGFN1,CASC2,SLIT2,LHX2,DNAJB5,QKI,MAP4K4,CNTN1,SUMF2,LETMD1,ABI3BP,ACBD5,MYRIP,NRG2,CRMP1,ANKRD44,GDA,SEC24C,ARHGEF10,MICAL2,ATRNL1,IPCEF1,RIMS4,VAC14-AS1,PDE4DIP,CNTNAP2,PLXNA4,DZIP3,PPP1R16B,APPL1,GREB1,CTNND2,RIMS2,DCAF4,RUBCN,CX3CR1,CCDC144A,CYBB,KIAA0408,GAPVD1,RASSF2,LIN54,MATR3,DGKB,DCC,ELMSAN1,DCTN1,C8orf34,ZEB2,ZBTB24,MFAP3L,KIAA0319,KLHL3,G3BP2,RABGAP1L,DLG2,DMD,DNM1,SLC29A4,DNM2,DOCK2,DPYSL2,ECM2,TOM1,E2F5,E2F6,EBF1,EDIL3,WDPCP,FAM135B,EDN3,SYT15,EFNA3,SH3GLB1,EGFR,MBNL2,ABI2,IRAK4,PLEKHA1,RGS17,BSCL2,ELN,USPL1,EPB41,EPHA5,GPHN,STX2,NCALD,CDHR1,ETV1,RTN3,DNAJC27,GMPR2,F3,CLVS1,SH3YL1,TUBA1B,PRMT5,ZNF589,SLC9B2,KIAA1109,FGF1,MEX3B,HPCAL4,SYNCRIP,NELFCD,EFCAB2,TMEM107,RASL10A,NSG2,CELF1,HHIPL1,ABLIM2,STAG2,GABRA5,GABRB1,GALNT15,GABRG2,BRPF3,GHDC,SEPT9,GATM,GCNT2,ADAM28,PCDH17,GGT7,PPARGC1A,RND1,HPGDS,SPIN1,GLS,MAP7D2,LUZP2,DCLK2,GNAL,GPD1,GPM6B,GPR19,GRIA1,GRIA2,ADAMTS13,GRIN1,GRM7,LINC01089,LINC00839,GSTM5,GSTT2,ZBTB49,MFSD2A,FAM107A,SLC2A6,GYG1,GPR45,ATXN2L,GABARAPL2,SYNPO,HNMT,HSD17B1,SOWAHA,RBPJ,LIX1,ZNF385B,KCNA6,KIF5A,KIT,CYP27C1,MAN2A2,MAPT,MBNL1,MBP,LDLRAD3,TM6SF1,MEIS1,PPM1L,POC1B,MN1,ADAM22,HS6ST3,MXI1,MYO9A,ZC3H12B,TBC1D25,CHAMP1,OGDH,CLDN11,ZDHHC22,CNTN3,PCSK2,PDE4D,ENPP2,SLC10A4,PFKFB2,GDAP1L1,PIK3CD,PLCL1,PCDH18,SCHIP1,PACSIN1,NXPH1,SH3KBP1,PPM1B,PPP1R1A,LRRN3,PRKCB,PRKCZ,MAPK10,CYBC1,PTCH1,BDNF-AS,MTMR10,ELOVL2,PXK,SPDL1,OCIAD1,PTPRD,ZSCAN2,ZNF793,RASGRF1,RBBP6,KHDRBS2,ZDHHC14,RDX,TRIM68,FIGN,RGS3,PRIMA1,ARHGEF10L,RIT2,SEC61A2,NUDT11,ZFHX4,TMLHE,EXD2,KLHDC8A,CARF,ROBO1,CCDC25,YY1AP1,PCMTD2,CCDC102B,RPE65,SNX22,NEK11,MCMBP,PRR5L,ADAL,MEG3,CLIP1,DGLUCY,ATXN2,SCP2,TRIM46,TRA2B,HSPA4L,PPM1E,AMBRA1,CTXN2,DZIP1,SLA,ZNF365,PREX2,RUFY2,PKNOX2,LRRC55,SLC6A11,SLC8A1,SLC8A3,CDK5RAP3,SLC15A2,TMEM132D,ELMO2,SLC20A2,LGI3,NAXD,MAST1,SMARCE1,MBD5,SNRPN,FAM126B,USP33,PDZD2,LHFPL4,BEX1,RBM26,NFASC,TROVE2,COLGALT2,NXT2,NCDN,GANAB,NECAB1,NUDT10,C3orf70,SYT1,FBXW11,ANO4,NEU4,ZFP90,ZEB1,TPCN2,GPRIN3,CYB561A3,RNF216P1,C18orf54,AP4E1,GPR161,TGFBR3,THBS4,TK2,ASXL3,DAAM2,TPM1,PRMT8,STXBP4,ZKSCAN5,CLHC1,AMOT,UCHL1,LINC00689,FLRT2,MEAF6,BEST1,TBC1D15,NSD2,SLC13A3,SLC47A2,ZNF28,TRIM9,CELF4,ZNF154,AMZ1,ZNF213,CA10,PRDM2,STOX2,ADAMTS9,URM1,NAV2,FAM47E,DOCK8,HNRNPA3,CAMK1G,NUP214,ADAMTSL3,TRAM2-AS1,RNF170,KLHDC1,PIANP,FXR1" MicroRNA hsa-miR-130b:mirSVR_highEffct hsa-miR-130b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.05E-152 5.91E-149 2.91E-151 2.68E-150 362 1401 "CLK4,NCKAP5,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,GPR158,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,SPARCL1,SPOP,SRPX,FAM135A,MRTFA,LRCH2,LCORL,USP28,PHF12,APAF1,API5,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,STX16,ATP2B1,ZNF583,NOL4,DPY19L3,ADAM23,TTLL9,BACH1,ADGRB3,NRP2,DST,SYNJ2,C5,CACNA1B,THSD7A,KALRN,SYT6,CAST,MAP7,CERS5,USP6,SEPT7,TIGD7,CFL2,KMT2C,ZFYVE9,PLAA,CLTC,FADS2,NIPBL,FHL5,CNR1,AKAP7,FAM149A,AKAP6,BTF3L4,TBPL1,ACBD5,MYRIP,HS3ST5,CLOCK,CREM,GDA,CSF1,LRIG1,CHD5,SOCS5,PDE4DIP,APPL1,PHF14,GREB1,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,LONRF1,SPATA2,YTHDC1,ZEB2,FBXL5,KIAA0319,CEP170,DDX46,RHOBTB1,WDR20,CPEB2,DPYSL2,ABCC5,ABCC9,GOLT1B,AASDH,SNX29,WDPCP,EDN1,EDNRB,KMT5B,EGR3,ASB3,PLEKHA1,CERCAM,PAN3,ENPP6,RABEPK,EPS8,DENND4A,CEP85L,RASL12,F3,ACSL4,TESK2,GORAB,MED12L,FGF11,FGF12,FGF14,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,FLT1,NBEA,TACC2,NPTN,MEGF10,GABRA1,HBS1L,B4GALNT1,ZNF274,NCKAP1,GAP43,ERAP1,MYOZ2,GCNT2,ARFIP1,ADAM28,RAB30,GLS,TNRC6A,KDM2B,MAP7D2,INSM2,LUZP2,RAB40B,FERMT2,PRUNE2,GPR34,RAPGEF4,GRB10,GRIA4,GRM1,GRM7,CIT,LINC00839,RNF165,TOX2,HNF4G,NEGR1,IRF8,MSL1,ZIC5,LRRCC1,USP54,IL11RA,ZNF678,CREG2,IPO5,LIG4,VWA5A,ARHGAP12,SMAD1,SMAD9,MAG,NAT8L,MAP4,MARK1,MATN3,MBNL1,MDM4,MOG,ERICH3,BCO1,MTR,LYRM9,MYO9A,ZNF862,MYT1,NAP1L1,NAP1L3,NEK1,NEUROD1,NFE2L2,CNOT4,OCRL,OMG,OPA1,GPR137C,PCSK5,PDE1C,PDE3B,PDGFRA,CCSER2,ST8SIA5,JAKMIP1,PLIN1,PURG,LRP12,POU3F2,CRLS1,PPP2R5E,PPP3CB,KANSL1,PKN2,PSD,PLPPR1,MTMR10,PTHLH,PTPRG,RAB5B,PID1,CEP97,RAD17,ATG16L1,RBBP8,ZDHHC14,RDX,RET,SLC25A36,RPRD1A,KLHDC8A,CARF,ROBO2,EPHA10,LRRK2,CNTNAP3,CLIP1,RTN1,SEMA6D,SCN3A,FAM19A1,TNFRSF19,PEAR1,SEC14L1,SOX6,ARX,KIF16B,MAGI3,CHD9,SYBU,ABLIM3,BTBD3,WDR47,RUFY2,SEPHS1,SLC8A1,CCDC88A,SHANK2,BTBD7,SNAP25,KIF13A,USP33,SON,MYT1L,TRERF1,SOX5,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,CLASP2,TROVE2,CLSTN2,POGZ,STOX1,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,NUDT10,PLCB1,SYN2,ANKRD28,ANKRD12,MTCL1,CAMTA1,CAMSAP2,UNC5D,FBXW11,CUX2,PCDHB4,TEK,FAM200B,DICER1,ZFPM2,ITGB3BP,SLC44A1,BHLHB9,ERCC6L2,TNFRSF1B,R3HDM1,CSMD1,TNS1,NPL,TPM4,SMUG1,TRPC3,TSC1,ANO5,UBC,FAM155A,SLAIN1,WRN,CFAP298,ZIC1,ZNF711,ZNF74,MKRN3,SPHK2,TCEAL7,REEP1,FSTL5,UPF3A,WNK1,PMEPA1,MAP3K12,MFF,LRP8,CSDE1,STOX2,PCDH15,KCNAB1,CAB39L,PLSCR4,C12orf4,RGS7BP,UBE3B,PHTF2,NHSL1,SLC39A12,FXR1,FRMD6" MicroRNA hsa-miR-224*:mirSVR_highEffct hsa-miR-224*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.15E-152 6.46E-149 3.17E-151 2.92E-150 391 1635 "RALGAPA1,SDE2,KCNH8,CLK4,NCKAP5,XKR4,SLC25A25,FMNL2,CCDC85A,PLEKHH1,KIAA1211,BEND6,MTA3,SLC24A4,GPR158,CASKIN1,OSBPL6,ALCAM,BCAR3,MRTFA,KIF6,CDC42BPA,DPP10,LRCH2,LCORL,PPFIA2,CNIH2,PKP4,DGKD,ALS2,SHTN1,CASK,ARHGAP5,ASCL1,ATP2A2,ATP2B1,B3GALT2,BLM,ST3GAL5,MTMR3,MTMR2,RAB29,KALRN,CANX,VXN,SPAG9,MAP7,NFS1,CCNH,TMEM257,C1orf52,LRBA,LGI1,L3MBTL4,DLGAP1,UBE2L6,RCBTB2,SRSF11,CHGB,CHM,KMT2C,C4orf33,NIPBL,CNR1,CNTN1,ARMC8,AKAP6,SLC4A7,ABI3BP,RTTN,ACBD5,ZFP28,HS3ST5,PREPL,ENTPD4,RBM39,HAPLN1,HINFP,ANKRD44,SNCAIP,VCAN,SOCS5,PLXNA4,SLITRK5,FGFR1OP2,ARHGAP24,LIN54,MATR3,KCTD8,DAPK1,ARMCX2,C8orf34,ZBTB24,MYEF2,ZC3H11A,RHOBTB1,SNAP91,KBTBD11,DLG2,GRIN3A,DMD,NR1D2,DMTF1,SLC12A6,CASP8AP2,DPYSL2,ABI1,DTNA,FAM78B,DNAJB6,DYRK1A,ABCC9,SEMA3D,RBM12,APH1A,MBNL2,KMT5B,ABI2,EGR3,AASS,GOLGA7,IRAK4,PLEKHA1,EIF1,EPB41L2,LRRC17,ZNF549,ETV1,VPS26C,RTN3,ADGRV1,EZH1,F5,ARMCX1,CLVS1,ACSL4,DLC1,CHST15,FDFT1,FER,OLFM1,FGF11,FGF12,PRKAG2,SUCO,SYNCRIP,FLT1,NBEA,SORBS1,SMC2,CSPG5,NSG1,NRG3,PHYHIPL,GABRB1,HBS1L,AHCYL1,RAPGEF6,GALR1,NCKAP1,DISC1,ATP8A2,LRRC37A6P,DNER,SULT1C4,SESN1,PCDH17,COPS8,SPIN1,GLS,TNRC6A,GLUL,ZNF638,INSM2,PRUNE2,GPM6A,GPM6B,STON1,GPR34,CECR2,PCLO,GRIA1,GRM5,RNF165,ZBTB49,LINC01551,UBE2QL1,GPR45,LINC01102,MIER3,HNRNPK,TLX1,CELF5,HTR2A,MSL1,IDH3A,SOWAHA,C5orf24,GAREM2,RBPJ,DOCK7,USP54,DIPK1A,SLC35G1,KCND2,KCNJ16,KCNK2,KCNN3,CREG2,KIT,KLRC3,CYP27C1,STMN1,NCOA7,MAOB,MATN2,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,ADAM22,ZNF92,MTTP,MYO9A,HNRNPM,NAP1L2,NCAM1,NDP,NDUFA5,NEUROD1,SLC11A2,HCN1,TBC1D25,IGSF11,ODF2,GPR88,PRTG,PDE3B,PDE4D,PDGFRA,BEST3,CDK14,A2ML1,ZFYVE21,TRHDE,RC3H2,EXOSC10,PRRX1,ING3,SPATA6,EPB41L4B,PPM1B,PPP2R5E,PRKACB,RAB39A,DCHS2,SNRK,TMEM260,PTPRB,PTPRE,PEX2,ACSM5,CCDC40,SH3TC2,OXR1,RASGRF1,HKR1,RDX,SLC6A15,KIF7,LGI2,CCDC82,ZNF532,RAVER2,CCDC25,RORB,RPL15,ZC3H14,ZNF671,MCMBP,ACER3,LRRK2,MEG3,CLIP1,ZNF331,SALL1,ATXN7,FAM19A1,FNIP1,IL17RB,RASA3,SGK1,KIF21A,PPM1E,DOCK10,SHC4,FNDC3A,SLC1A3,FAM81A,RPH3A,DHX30,RUFY2,CCDC88A,BTBD7,SLC22A4,CDK5RAP2,SMARCE1,RCOR3,SNAP25,SNCA,MBD5,SNRPN,UNC80,WDTC1,NMNAT2,HECW1,MYCBP2,KDM4C,TEX2,LMO3,SRPK2,PBLD,POGZ,SAMSN1,DIP2A,SULF2,VPS13A,ADAMTS17,FNDC9,SYN1,COBL,C12orf76,MTCL1,CAMTA1,TCEA1,ZEB1,RPGRIP1L,SYNE1,SLC19A3,SIRT1,AP4E1,TIAM1,TJP1,TK2,BHLHB9,ZFP91,HEY2,KAT6B,CDK20,TPM3,ZNF384,RUNDC3B,PRR18,TUBB1,CADM1,FAM155A,UBE2H,FLRT1,LAT2,PORCN,CLDND1,XRCC4,PCDH20,ZIC1,ZIC2,KCNT2,LYPD6,ZNF177,SYNC,UPF3A,MAP3K12,LRP8,CSDE1,LINC02210,ADAMTS9,TMEM178A,MDH1B,CAB39L,WNK3,PDSS2,EPM2A,DNAH10,FAM13C,MRPL47,PAK5,JMJD1C,FRMD6,NETO2,SLC4A10" MicroRNA hsa-miR-625*:mirSVR_lowEffct hsa-miR-625*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-152 6.57E-149 3.21E-151 2.95E-150 359 1378 "KCNH8,ACLY,ARID1A,CSMD3,FMNL2,SLITRK1,CCDC85A,TMCC3,ADD3,ERMN,PLEKHH1,PTCHD1,ADRB2,BEND6,NLGN4X,ZNF608,CASKIN1,OSBPL1A,CC2D2A,C1QTNF3,MARCH4,PCDH10,FAM135A,OGT,DPP10,LCORL,MAP4K3,SMIM29,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PARG,LRRC4C,SHTN1,ARHGAP5,LINC00173,STK33,ASPA,ZBTB10,B3GALT2,BACH1,DST,BTK,MYRF,CACNA1D,PTBP2,CANX,VXN,VSTM2A,CH25H,RUNX1T1,LDB2,MTMR7,INA,CD38,REPS2,DCLK1,ZNF445,TIGD7,NOG,UBE2L6,SRSF11,SOCS6,CHN1,NDST3,LHX2,CLCN3,CLTC,DNAJB5,C4orf33,CNN3,CNR1,IQCK,ARMC8,COL4A5,BAG4,MFSD4A,RBM39,CREB5,SNCAIP,ATRNL1,VCAN,FAM169A,KIAA0040,UBXN2A,PUM1,CCDC144A,DOCK4,ARHGAP32,LONRF1,LIN54,TMEM170A,C8orf34,ZEB2,TIAM2,KIAA0319,FBXO25,ALKBH8,RHOBTB1,SPOCK3,WDR20,CCDC3,CDON,DRP2,PDCD6IP,DTNA,DNAJB6,ABCC9,EBF1,TMTC1,RBM12,PHF20L1,KMT5B,EGR3,GOLGA7,ASB3,PCOLCE2,VPS13B,GPHN,ZNF549,MRVI1,F3,EFEMP1,DLC1,SEC24B,FER,POLR1B,FGFR3,POLK,UBE2E3,FOXG1,CAP2,IQCG,TACC2,UFM1,PDLIM5,ATP6V1H,KHDRBS3,TVP23A,ZMAT1,GABRA2,CHL1,RAPGEF6,NCKAP1,MTHFD2,GATM,GHR,PPARGC1A,GK,GLRB,GPR75,TOX3,CBX1,KDM2B,LUZP2,DCLK2,RAB40B,GPM6A,PRLHR,CECR2,PCLO,NR3C1,GRM3,TMEM25,ZBTB49,RABL2A,LINGO1,RASSF8,ZHX1,MAN1B1,FRMD3,LINC01102,ELOVL5,HMGB1,HNF4G,ZDHHC15,C5orf24,IGFBP1,ZIC5,RBPJ,ZNF678,SLC35G1,KCNC1,KCNC2,KCNJ10,KCNK1,KIF5C,IPO5,LAMP2,LIG4,HECTD2,PIK3AP1,MARK3,AQP11,MBNL1,LRP1B,MEIS2,SRSF12,MIA2,MID1,MITF,MRPL42,ADAM22,MYO5A,MYO9A,NAP1L1,NAP1L2,NAP1L3,ZC3H12B,NDUFA5,OTOGL,CNOT4,NTRK2,NUCB2,GPR88,PAH,DPY19L2P2,PDE3A,PDE4B,SLC10A4,PFKFB2,GPSM2,PCDH18,PDZRN4,STRN3,PRRX1,SPATA6,SH3KBP1,MED1,CRLS1,PPP2R5E,PPP3CA,KANSL1,RAB39A,SNRK,CNTLN,ANKHD1,PTHLH,TMEM260,OCIAD1,PTPRG,USP47,FAM184A,NWD1,ZCWPW1,RASGRF2,FEZF2,RBBP8,RADX,BSDC1,ZMAT4,TTLL7,RPRD1A,ZFHX4,TMLHE,CCDC102B,RPL15,FBXW7,ATXN7,FNIP1,SLC30A10,GALNT10,MRAS,NLGN4Y,KIF16B,CPEB3,SHC4,FNDC3A,SLITRK3,SYBU,NLGN1,NUBPL,PPP4R3A,SLC8A1,RAB3GAP1,SLC8A3,ARHGEF40,SHANK2,ELMO2,BTBD7,TET1,GKAP1,ANKRD36,MBD5,SNRPN,USP33,DOP1A,SOX5,BDP1,SOX11,EMC1,SPP1,BEX1,SPART,SRPK2,TAB2,NKAIN2,ERBIN,NECAB1,ARHGEF9,TAF9,UNC5D,ADGRL3,KLHL4,ANO4,EHBP1,ACSL6,TRIM2,WDR7,SYNE1,DOCK9,PCDHB10,PCDHA5,ZFPM2,TIAM1,ZFP91,R3HDM1,TP53BP1,TPM1,NPL,SYNPO2,STXBP4,TRPC1,TRPC3,RFTN2,TUB,SGK3,SLAIN1,OSBP2,CCDC14,NSD2,PCDH20,ZIC1,ZNF711,KCNT2,ZNF154,FSTL5,FTSJ1,DHX33,SLC30A4,STOX2,PRDM8,PRDM10,SCG2,PCDH15,FIP1L1,CAB39L,PDSS2,FAM13C,RTN4,PAK5,PHTF2,FBXO36,ADAMTSL3,JMJD1C,SLC39A12,KLHDC1,FXR1,SLC4A10,CPNE4" MicroRNA hsa-miR-548n:PITA hsa-miR-548n:PITA_TOP PITA 1.60E-152 8.97E-149 4.35E-151 4.01E-150 309 1011 "FMNL2,SLC12A5,USP31,PWWP2A,NLGN4X,ZNF608,KLHL13,TBC1D14,OSBPL8,ZNF578,MARCH4,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,API5,PPP4R4,TMEFF1,CAPRIN2,BRINP2,ZBTB10,NUMB,DDX3Y,SLC4A4,ATP2A2,ATP2B1,DOCK11,BCL2L2,CDK5R1,FUBP1,JAZF1,LDLRAD4,FOXK1,CACNB2,CALB1,PTBP2,LRBA,REPS2,LGI1,DLGAP2,NUMBL,CFL2,SRSF11,FOXN3,SOCS6,NRXN1,QKI,CNR1,ARMC8,BTF3L4,AKAP5,SLC4A7,AHCTF1,CDC42BPB,CREB5,CS,SNCAIP,TENM4,LRIG1,CSNK1E,DZIP3,ERC2,PLCXD3,CTNND1,PUM1,USP6NL,HDAC4,ZFYVE16,MAML1,PABPC5,ELMSAN1,ZEB2,MYEF2,SACS,G3BP2,DLG3,RAB39B,DMTF1,DPYSL2,GNE,DYRK1A,GOLT1B,EDIL3,YAF2,SH3GLB1,MBNL2,KMT5B,EGR3,ELAVL2,ELAVL3,CALCRL,PAN3,KCNMB2,ERBB2,ETV1,RTN3,EYA1,CACNG3,TAOK3,SEC24B,FOXG1,FOXF2,NBEA,PDLIM5,FAM49B,STAU2,STAG2,MEGF11,GAB1,GABRB3,CAB39,MTHFD2,ACSS1,GATM,AHDC1,TCERG1,TOX3,PCDH11X,GNAO1,GPD2,GPM6A,RAPGEF4,TPPP,GRB10,GRIA2,CIT,FAM19A2,CELF3,HAS2,ATXN2L,KLF12,BACH2,MIER3,HMGCR,HNF4G,IGFBPL1,NEGR1,HSF2,C5orf24,BRINP3,INSM1,ITGAV,JAK2,KCNA1,KCNC2,KCND2,KCNK1,KCNK2,KIF2A,SMAD1,MARK1,CHIC1,LRP1B,MEF2C,MEIS1,MEIS2,KITLG,ERICH3,ZNF680,PABPC1L2A,HNRNPM,NEUROD1,NF1,NFE2L2,NOVA1,NRCAM,HCN1,IGSF11,OCRL,CLDN11,GPR137C,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,XRN1,LRP12,SCHIP1,IRX1,PPP2R2C,PPP2R5E,PPP3CA,PRKACB,CEP41,PKN2,MAPK4,EPDR1,SNRK,PTCH1,PTPN13,PTPRG,PTPRN,FAM120C,TTC13,PID1,RAD52,ATG16L1,ZNF493,REV3L,RIC8B,NUDT11,ZFHX4,SETD5,ROBO1,RORB,LGR4,HUNK,SOX8,CLIP1,RTN1,CCDC112,SATB1,ATXN1,SCN3A,SOX6,TRA2B,ZFP30,PPP1R9A,PPM1E,CPEB3,MYO18A,NLGN1,WDR37,BTBD3,WDR47,FAM214B,SEPHS1,SLC8A1,CCDC88A,SLC20A2,CPEB4,SMARCE1,RIMS1,CABCOCO1,TMCC1,PDZRN3,SON,PDZD2,SOX11,SP4,LHFPL4,KDM4C,PEG10,ZNF423,ARHGAP26,CDK19,RBM26,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,VAMP1,ADAMTS17,PLCB1,ATP11A,ANKRD12,CAMTA1,TAL1,CAMSAP2,FAM208A,DMXL2,SATB2,TCF7,RPGRIP1L,TCF12,DICER1,ZNF106,SLC44A1,HEY1,NR2E1,HEY2,RIMBP2,KAT6B,RBFOX2,TPM1,RGMB,TRPC1,TRPS1,UBE3A,SLAIN1,FLRT2,MEAF6,VLDLR,PCDH20,ZIC1,ZIC3,ZNF711,CELF4,ZBTB38,TMEM237,ZFAND5,EMSY,STOX2,PRDM10,ADAMTS9,PCDH15,NAV3,WNK3,PARP11,RGS7BP,FZD3,PAK5,PHTF2,FRMD6" MicroRNA hsa-miR-26b:mirSVR_lowEffct hsa-miR-26b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-152 1.20E-148 5.78E-151 5.32E-150 424 1919 "KCNH8,ARID1A,KLHL32,AXIN2,SLC12A5,RNF150,ADRB2,DPY19L2P4,NLGN4X,SLC44A5,MTUS1,KCTD16,WDR35,LRRC7,ALAD,SPARCL1,ABCD2,ARHGAP20,PCDH10,FAM135A,SYT13,AMPH,AMT,OGT,ANK2,PPFIA4,PPFIA1,PKP4,EPB41L5,GPAM,ALS2,API5,USP37,APP,LGR5,PPP4R4,CASK,ARHGAP5,ASPH,ATM,NOL4,MYOM1,DOCK11,SEC11C,NRP2,CDK5R1,MTMR2,CACNA1G,NIPA1,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,CHRNB2,SLIT2,RAB28,PPT2,C4orf33,NIPBL,CNTFR,AKAP6,COL9A1,AKAP5,SLC4A8,ZFP28,CP,CPS1,FAM171B,PREPL,CREM,ANKRD44,SUSD5,ATRNL1,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,RIMS2,GPSM1,EDRF1,CCDC144A,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,TOX,LIN54,MATR3,DGKB,PABPC5,DNAL1,ARMCX4,ARMCX2,YTHDC1,C8orf34,ZBTB24,ELMO1,KIAA0753,KLHL3,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RABGAP1L,RAB39B,DYNC1I1,CPEB2,DOCK2,ABI1,DRP2,ECM2,MAMLD1,DYRK1A,ABCC9,GOLT1B,AASDH,EDIL3,EDNRB,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,EML1,C8orf37,DCTN4,USPL1,SEZ6,ENPP6,GPHN,TMEM74,CDKL3,EYA1,MRVI1,F3,F5,F8,AMZ2,WAC,ACSL4,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,PRKAG2,POLK,UBE2E3,IP6K2,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,PHYHIPL,ZMAT1,GAB1,GABRB3,GABRG1,HBS1L,BRPF3,FAM120B,NCKAP1,GATM,IGSF5,FAXC,MSTN,NFU1,PCDH17,MALT1,TCERG1,SPIN1,GLI2,PCDH11X,FERMT2,GPM6B,GPR12,GPR22,NUDT21,GPR37,TMEM121B,CECR2,PCLO,RAPGEF4,GRIA2,PLCD4,GRIK2,ATE1,TMEM25,ZBTB45,GUCY1A1,RASSF8,C1orf94,DDX19B,ARHGAP36,ELOVL5,SCRG1,HNMT,HNRNPK,AGFG1,HSPA1L,HSP90AA1,SMAP1,IGF1,IGFBP1,DOCK7,SCIN,IL11RA,IL12A,ZNF678,INPP5B,ZNF385B,JAK2,SLC35G1,METTL21A,KCNB1,KCNH1,KIF5C,IPO5,STXBP5,KTN1,LRRC4B,STMN1,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,MOBP,SAMD5,MSI1,MSRA,MT1M,CTNNA3,LAYN,MYO5A,NAP1L3,NEFH,NEUROD1,NOVA1,SMIM11A,OPCML,OPHN1,KCNK10,PCDHGC3,PCMT1,PCSK5,PDE4B,PDGFRA,PDYN,PENK,PFKFB2,GDAP1L1,PIK3CD,A2ML1,SCHIP1,SH3KBP1,CCDC144B,LRRN3,PPP2R5E,PRKAB2,RASGEF1B,PRKACB,RELN,SNRK,CNTLN,PTCH1,ANKHD1,UHRF1BP1,BDNF-AS,TMEM260,PTPRB,OCIAD1,EML5,PTPRE,PTPRH,PEX2,ZSCAN2,TUG1,PID1,ACSS3,ATG16L1,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,RET,REV3L,ERI2,GTDC1,SEC61A2,RNASEL,LGI2,CCDC82,EXD2,C12orf49,ALG9,RPE65,SNX22,ACER3,RPS6KA2,KCNIP3,WLS,YJEFN3,RYR3,ATXN2,FAM19A1,TNFRSF19,SELL,ASRGL1,SUPT20H,ITSN1,FERMT1,NTNG1,MAGI3,FNDC3A,SLITRK3,CNKSR2,ST3GAL3,NUBPL,WDR37,PPP4R3A,LRRC55,SLC6A8,SHANK2,SLC12A2,SLIT1,SNRPN,FAM126B,TRERF1,SOX2,KIF21B,BDP1,KDM4C,ERC1,PEG10,RBM26,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,FGD4,SYN1,COBL,DDHD2,CAMTA1,ALG1,ANO4,DMXL2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,PSD3,TEX15,FAM200B,SIRT1,ZFPM2,ITGB3BP,ZNF106,HHIP,AKTIP,SLC44A1,GZF1,TLR4,SEZ6L,TPD52,NPL,RGMB,SYNPO2,TRIO,TMEFF2,GORASP1,FLRT2,VAV2,BEST1,WIPF1,NSD2,XPO1,ZBTB14,FMN2,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,PCDH15,URM1,KCNAB1,CAB39L,SLC17A6,MVB12B,DOCK8,PHTF2,FBXO36,ACTR3B,SSPN,NETO1,CPNE4" MicroRNA hsa-miR-15a:mirSVR_highEffct hsa-miR-15a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.67E-152 1.50E-148 7.20E-151 6.63E-150 369 1460 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,CSMD2,GALNT13,AXIN2,CDC7,ADRB2,AP2A1,DISP3,LRRC7,ALAD,SRPX,ARHGAP20,OGT,ANK2,CNTNAP1,GPAM,ALS2,BCAS1,PPFIA3,APP,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,DDX3Y,SLC4A4,TTLL9,MPDZ,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,BTRC,CA8,CACNA1B,CACNA1E,KALRN,PTBP2,NGB,CANX,VSTM2A,CAST,MAP7,RUNX1T1,ARHGEF1,CDC27,CDC42,TIGD7,CHM,CHRNA4,PPT2,CLCN3,CLCN4,COG1,TPP1,QKI,BTF3L4,SLC4A7,SLC4A8,ABI3BP,TBPL1,TCEAL2,MYRIP,MFSD4A,SEC31B,PREPL,CRYM,LRIG1,FEZ2,MICAL2,SOCS5,PDE4DIP,ERC2,CFAP61,ZSCAN23,USP6NL,CX3CR1,ARHGAP32,GAPVD1,RIPOR2,DCAF8,PHF19,KCTD8,IP6K1,GIT2,ARMCX2,YTHDC1,JAKMIP2,C8orf34,PLEKHM1,SMG7,SPOCK3,NTM,DLG2,DNM1,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SIDT2,RBM12,PHF20L1,MBNL2,PLEKHA1,EN2,RCAN2,DENND4A,CEP85L,SPEG,CDHR1,RTN3,EYA1,NRN1,ACSL4,RACK1,FGFR1,SUCO,RGPD5,SLC37A3,PDLIM5,ARFGAP2,CELF1,CSPG5,NSG1,STAU2,GALNT15,ARPP21,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,SPIN1,TNRC6A,INSM2,GNAS,FERMT2,GPD2,PCLO,GRM7,RNF165,WIF1,RASSF8,ZHX1,FRMD3,HTR2A,MSL1,RBPJ,NIM1K,ZNF678,INPP1,NME9,SLC35G1,KCNC2,KCND2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,SYTL4,ARHGAP12,PACRG,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MEST,MN1,MSR1,THYN1,MYBPC1,RTL5,PABPC1L2A,NAP1L2,NDP,SLC11A2,NTRK3,ODF2,OMG,GPR137C,CNTN3,ETFRF1,PCDH9,PCMT1,PDE3A,PDE4D,PDPK1,SLC10A4,BEST3,PIK3R1,JAKMIP1,PLP1,PLXNB3,PSAT1,PRRX1,MAGEL2,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,PRKCG,PKN2,GDPD1,MASP1,RELN,CNNM2,SYTL2,GDPD2,SNRK,PIGG,CNTLN,PTHLH,STK32A,ZSCAN32,PTPRD,EML5,PEX5,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,ZDHHC14,RDX,SLC6A15,RET,RFX4,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,ARMH4,FBXW7,SYNDIG1,ABCA11P,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN2A,SCN3A,SCN8A,ELMOD1,SLC30A10,COPZ1,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,SHC4,NLGN1,ST3GAL3,ANKRD6,FAM81A,ARHGEF40,KBTBD4,SLC20A2,SLC22A4,TET1,CPEB4,SLN,RCOR3,SNAP25,MBD5,SNRPN,UNC80,SON,MYT1L,UNC5B,ZC3H13,KIF1B,TSPYL2,NPAS3,NFASC,PHLDB1,ACSBG1,PRRC2C,SYNE2,VPS13A,C3orf70,SYPL1,SYT4,C12orf76,KAZN,ADGRL3,WWC1,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,TGFBR3,DDHD1,NR2E1,ERCC6L2,HEY2,TMOD1,KAT6B,TP53BP2,TPM2,RUNDC3B,TRPC1,TRPC3,CADM1,AMOT,LGI4,TRIM9,FSTL5,EML6,ANKS1B,SLC30A4,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,ADAMTSL3,SNX14" MicroRNA hsa-miR-514b-3p:mirSVR_lowEffct hsa-miR-514b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-152 1.80E-148 8.63E-151 7.95E-150 389 1623 "RALGAPA1,CLK4,CSMD3,KLRC4,TMCC3,BRAP,PNMA8B,SORCS1,KIAA1211,BEND6,AP2A2,MTUS1,KLHL13,PCDH19,HACE1,WDR35,LRRC7,SEMA6A,ALCAM,MARCH4,PCDH10,BBOX1,UNC79,FAM135A,GPRASP2,LRCH2,ANK3,C6orf89,LCORL,USP28,PPFIA2,PPFIA1,PKP4,ANXA7,UPRT,NT5C3B,PHYHD1,USP37,AQP4,PPP4R4,RGS20,CADPS,LINC00173,ASPH,TMEM108,ATP1B3,ATP2A2,ALDH7A1,ADAM23,LINC00847,BCHE,BMP7,SYNJ2,SCAPER,C5,IL33,VSTM2A,ISPD,CLDN10,USP6,MTMR7,TMEM257,REPS2,CDC27,CDH8,MAGI1,SOCS6,CASC2,MS4A7,SYNPR,CNOT8,IGLON5,ARMC8,AKAP6,MAGED1,ZNF521,FAM171B,PNKD,C2CD2,CREM,GDA,SNCAIP,RGS6,ARHGEF10,MICAL2,VCAN,PPP1R16B,ERC2,PUM1,ECE2,FGFR1OP2,KATNAL2,DCAF8,MATR3,DNAL1,DCC,JAKMIP2,HEPH,FBXL5,GSDME,SGSM2,DLX1,EXOG,SLC29A4,DMTF1,DPH1,DRD1,DTNA,TOM1,ABCC5,DNM1L,EDN1,EDN3,ATL1,FCF1,TMTC1,FSD1L,SH3GLB1,ABI2,EIF5,MRNIP,EML1,CALCRL,EIF1,EMX2,RCAN2,EPHB1,DENND4A,NCALD,ZNF549,MRPL37,ETV1,KATNAL1,TAOK3,FCGR1A,CEP78,FDFT1,ZNF589,PRKAG2,MEX3B,SGIP1,SMC2,ATP2C1,KHDRBS3,ABLIM2,OGA,DKK3,GAB1,GABRA1,GABRG2,HBS1L,ZNF234,SYT17,C15orf41,DISC1,ATP8A2,INPP5K,IGSF5,GCNT2,MSTN,ADAM28,GFRA1,GLDC,TNRC6A,ZNF638,GNAL,GPD2,PRUNE2,GPM6A,LILRA1,CCDC184,GPR22,GPR34,PCLO,GRID1,RFFL,GRM5,GRM7,FAM19A2,ZBTB49,MFSD2A,WIF1,MAEL,ZHX1,PTGDR2,HRH3,BACH2,TLX1,HSPA1L,MSL1,ZNF546,RBPJ,DOCK7,KCND2,KCNMA1,KIF5A,IPO5,STXBP5,LAMA2,STMN1,INSYN2,SFXN5,SYTL4,LSS,MBD1,MBNL1,SYT9,LRP1B,WDR49,ZNF680,GIT1,CTNNA3,HS6ST3,MYT1,HNRNPM,NAP1L2,NASP,NDUFA5,SFR1,NOVA1,NPTX1,SLC11A2,NRCAM,NUCB2,OCRL,CHAMP1,OMG,SNTG1,PAK3,PCDH8,PCMT1,PCSK1,PDE4D,SLC10A4,BEST3,SERPINI1,NOMO2,XRN1,PLCB2,C11orf49,PRRX1,ING3,NXPH1,PPP2R2B,CRLS1,PPP3CB,PRKAB2,PKIA,PRKAR1B,PRKCB,PRKCZ,MAPK4,MAPK8,MAPK9,PRPSAP2,VPS13C,CNTLN,PLPPR1,OCIAD1,PTPRE,PTPRN2,PTPRO,RALGDS,FAT4,BSDC1,RFX4,RGS3,RGS7,TTLL7,RIT2,RIC8B,RPE65,RPL15,ZNF671,LRRK2,CNTNAP3,ATAT1,TRAPPC13,SEMA6D,SCN2A,SCNN1D,SLC30A10,SOX6,SUPT20H,TRA2B,SCG5,ITSN1,PPM1E,CPEB3,FHOD3,ST6GAL1,ST3GAL3,PPP4R3A,SLC6A1,ZNF430,SLC9A5,TMEM132D,SCMH1,ATF7IP,SLCO1A2,IFT122,ANKRD36,SNAP25,MBD5,LMBRD1,SNRPN,USP33,WDTC1,MYT1L,SP4,MYCBP2,TEX2,ZNF423,ZBTB43,RBM26,TAB2,POGZ,SAMSN1,EPB41L3,LRRC4,SSPO,MAPK8IP3,PHLDB1,KANK1,SULF2,SYPL1,TACR1,PJA1,TAL1,CAMSAP2,UNC5D,ACSL6,TCF4,PHF24,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,SIRT1,CRB1,AP4E1,SLC44A1,TIAM1,RELL2,BHLHB9,BEX4,CSMD1,PIK3R5,TP53BP2,SYNPO2,AMACR,FNDC5,ANKRD20A2,TTC3,GORASP1,BCL2L13,GUSBP1,ZBTB14,ZIC1,ZNF708,KCNT2,GPR158-AS1,TCEAL7,POLR3H,DPYSL5,CA10,EMSY,SLC38A1,LINC02210,HPS4,SLC17A7,C12orf4,PDSS2,SMIM8,FBXO36,KLHDC1,FRMD6,IFT88,NETO1,SLC4A10,GAN,FAM198A" MicroRNA hsa-let-7g*:mirSVR_highEffct hsa-let-7g*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.24E-152 1.82E-148 8.66E-151 7.98E-150 336 1207 "RALGAPA1,DGCR6,KCNH8,CLK4,ARID1A,KLHL32,DSCAML1,AXIN2,ADRA1D,BEND6,HECW2,OSBPL1A,TBC1D14,LRRC7,SPARCL1,ABCD2,PCDH10,UNC79,FAM135A,SYT13,OGT,ANK1,MAP4K3,CNIH2,SUGT1P4-STRA6LP-CCDC180,MAGEE2,ALS2,PHYHD1,BCAS1,APP,TMEM263,DACT3,CHRD,RASL11B,ATP2A2,ADGRB2,BCHE,DCAF5,NRP2,SYNJ1,MTMR2,OSGIN2,BSN,IL33,CACNA1D,KALRN,PTBP2,MAP7,AP4M1,LRBA,CDH10,MAGI1,SRSF11,CHN2,NDST3,LHX2,CLCN4,LY86,AKAP7,IQCK,LETMD1,SLC4A7,AKAP12,HAPLN1,CS,LRIG1,MICAL2,PLCH2,SOCS5,PDE4DIP,SLITRK5,ST18,USP6NL,HDAC9,TCAF1,KIAA0586,IST1,TOMM20,IP6K1,ZEB2,CEP170,MAGI2,ALKBH8,SMG7,SNAP91,DLX1,HS3ST2,DNAH9,NR1D2,CDON,CPEB2,DTNA,ABCC5,E2F5,EBF1,WDPCP,EDNRB,PHF20L1,MBNL2,EGR3,ELAVL2,PLEKHA1,RGS17,EPHA5,GPHN,CEP85L,RTN3,EYA1,CLVS1,EFEMP1,DLC1,CEP78,FGF13,SYNCRIP,SLC37A3,DCTN2,C2orf88,NBEA,SORBS1,HVCN1,STAMBP,CAMKK2,CSPG5,ZNF512,STAG2,MEGF11,GABRA2,GABRA5,GABRB1,ZMYND11,GALR1,SALL3,NEK6,ZNF559,KIAA1841,AHDC1,GFAP,PPARGC1A,KIRREL3,GLI2,KDM2B,GNAL,FERMT2,GPM6B,GRB10,DIDO1,C1QL4,GRIK3,GRM7,ZNF496,CIT,PTPN5,KAT7,LINC01551,LINGO1,GYG1,ARHGAP36,BACH2,HMGB1,ZNF491,SHISA6,SMAP1,HTR5A,SOWAHA,KNDC1,RIPPLY2,INSM1,LRRTM3,ITGAV,JAK1,METTL21A,KCND2,KCNH2,KCNJ16,KCNK1,KCNK2,KIF5C,STXBP5,LAMP2,VWA5A,ARHGAP12,NCOA7,LSS,ASPRV1,NAT8L,MAP4,MBNL1,SHC3,HS6ST3,NAP1L1,NCF2,OTOGL,NODAL,NPTX1,HCN1,NTRK2,NTRK3,CLDN11,PBX1,PCDH8,PCSK1,PCSK5,PDGFRA,ENPP2,NLGN3,CAMKV,PIK3C2A,ZNF655,FAM218A,ZFYVE21,ING3,NXPH1,TATDN3,PPP2R5C,SAMD9,SNRK,PTK2,TMEM260,USP47,RASGRF1,FEZF2,REV3L,RFX4,RGS7,PRIMA1,ARHGEF10L,SLC25A36,PBRM1,ZFHX4,TMEM100,SNX22,NEK11,MAP6D1,LGR4,MEG3,TRAPPC13,RMI1,SALL1,SCN2A,SGK1,ITSN1,SH3GL2,ARX,KIF16B,CPEB3,DOCK10,NTNG1,FNDC3A,SLITRK3,SYBU,ANKRD6,WDR37,SLC20A2,SLC22A4,RIMS1,SNCA,MBD5,SNRPN,KDM4B,PDZD2,MYT1L,SOX10,KDM3A,MYCBP2,TAB2,ATP10B,CLASP2,TROVE2,ZNF302,EPB41L3,ZC4H2,LARP4,NKAIN2,ERBIN,STAU1,NSFL1C,NUDT10,DNAJC9,PLCB1,MMS19,DDHD2,CAMTA1,TAL1,FAM208A,ADGRL3,TCF7L2,ZEB1,WDR7,DOCK9,RALYL,FAM189A1,PCDHB4,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SLC44A1,TJP1,TMPO,R3HDM1,KAT6B,SEZ6L,TPM3,RGMB,TRIO,EIF4ENIF1,DNAJC12,FLRT1,PLEKHH2,BCL2L13,VLDLR,ZIC2,ZIC3,MKRN3,ZNF142,REEP1,EMSY,MDH1B,NAV3,PCBP4,MPPE1,MVB12B,PDSS2,FAM13C,KAT6A,FBXO36,FAM219B,JMJD1C,VANGL2,FXR1,NETO2,SENP7" MicroRNA hsa-miR-27a-3p:TargetScan hsa-miR-27a-3p TargetScan 4.24E-152 2.38E-148 1.12E-150 1.04E-149 311 1028 "CPNE2,ABAT,ASIC1,ACLY,ABHD6,ELFN2,ADCY6,ADD1,ADD3,PLEKHH1,PTCHD1,MTA3,HECW2,KCTD16,AK2,PCDH10,PITPNM2,ANK1,ANK2,ANK3,PPFIA2,APAF1,APBA2,APC,GPAM,PDXK,ARNTL,PDE8B,CAPRIN2,NCOA1,ALDH4A1,ATP1A2,ATP2B1,RNF182,NOL4,DPY19L3,DOCK11,BCL7A,NRP2,KSR1,CDK5R1,FUBP1,JAZF1,LDLRAD4,CA12,CACNA1A,CACNB2,DIRAS1,CAMK2A,CAMK2D,BRSK2,RUNX1T1,CCNT1,C1orf52,LRBA,REPS2,CDC25B,LONRF2,FOXN3,KMT2C,DLGAP3,PLAA,CLCN3,NRXN1,QKI,IGLON5,CNN3,ARMC8,CABP1,LETMD1,COL11A2,SEC31B,CDC42BPB,C2CD2,HAPLN1,CSF1,RIMS4,CNTNAP2,ERC2,CTH,KIAA0513,LONRF1,LIN54,RIMS3,DGKG,DCC,ELMO1,MAGI2,KBTBD11,RAB39B,NR1D2,CDON,ARRDC4,DTNA,DYRK1A,E2F6,EDNRA,HIPK3,FEM1B,EFNA2,FAM13A,EBI3,MBNL2,EGR3,LPAR6,EIF5,ELAVL2,RGS17,EML1,PAN3,EN2,EPB41,EPB41L1,RCAN2,MTSS1L,EPS8,NCALD,CEP85L,DNAJC27,EYA1,F3,CACNG2,MED12L,KIAA1109,FGF1,FGF14,AMOTL2,PCYOX1,RGPD5,FOXO3,ANKFY1,NPTN,CELF1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,GAB1,GABRB1,GABRB3,CAB39,BRPF3,NEK6,GCNT2,MSTN,CSDC2,GK,GPR75,INSM2,KCNMB4,GPD2,B4GALNT4,ADAP1,CECR2,DIDO1,GRIK3,GRIN2D,GRM5,PTPRT,KIF3A,MFSD2A,FAM222A,HAS2,KLF12,MIER3,HMGCR,HNF4G,AGFG1,MSL1,IGF1,IL6ST,INPP1,DIPK1A,METTL21A,KCNA4,KCNA6,KCNC2,KCNJ3,KCNK2,KCNN3,KPNA5,LIFR,NCOA7,LSAMP,MAN2A2,MAPT,MARK1,AQP11,MATN3,MDFI,CHIC1,MDM4,MEF2C,MEIS2,KITLG,MITF,MMP16,MN1,MSI1,MDGA1,LAYN,MYT1,NCAM1,NCAM2,NF1,NFIA,NFE2L2,ALDH1L2,NOVA1,NRCAM,OPA1,OPHN1,PAX6,PCDH9,CDK18,PDE3A,PDE3B,PDGFRA,PDPK1,CDK14,CDIP1,POU3F2,PKIA,PRKCB,MAPK10,GRAMD1C,RELN,CNNM2,NKAIN1,MARCH1,FAM184A,RASGRF1,RET,FIGN,RFX3,C12orf49,ALG9,ROBO1,FBXW7,LGR4,HUNK,RXRA,FAM192A,CASC3,FAM102A,PPM1E,ARX,CPEB3,MAGI3,FNDC3A,CCDC92,FAM81A,PKNOX2,CPEB4,EPC1,RCOR3,MBD5,FAM126B,KDM4B,SCN3B,KIF21B,KDM3A,MYCBP2,PEG10,NPAS3,NFASC,C11orf87,ATP10B,CLSTN2,COLGALT2,LARP4,NXT2,MAPK8IP3,GSE1,FAM168A,ACSBG1,PRRC2C,ANKRD12,PDLIM2,KLHL4,SATB2,RPGRIP1L,RALYL,NSD1,CRTC1,GPRIN3,FRYL,GZF1,NACC2,CBX5,NR2C2,PRMT8,CADM1,GORASP1,FLRT2,PLEKHH2,BCL2L13,MICU3,CA10,MAP3K12,NAV2,MVB12B,FZD3,CERS6,ADAMTSL3,JMJD1C,ADAMTS10,FRMD6,NETO1,RNF146" MicroRNA hsa-miR-27b-3p:TargetScan hsa-miR-27b-3p TargetScan 4.24E-152 2.38E-148 1.12E-150 1.04E-149 311 1028 "CPNE2,ABAT,ASIC1,ACLY,ABHD6,ELFN2,ADCY6,ADD1,ADD3,PLEKHH1,PTCHD1,MTA3,HECW2,KCTD16,AK2,PCDH10,PITPNM2,ANK1,ANK2,ANK3,PPFIA2,APAF1,APBA2,APC,GPAM,PDXK,ARNTL,PDE8B,CAPRIN2,NCOA1,ALDH4A1,ATP1A2,ATP2B1,RNF182,NOL4,DPY19L3,DOCK11,BCL7A,NRP2,KSR1,CDK5R1,FUBP1,JAZF1,LDLRAD4,CA12,CACNA1A,CACNB2,DIRAS1,CAMK2A,CAMK2D,BRSK2,RUNX1T1,CCNT1,C1orf52,LRBA,REPS2,CDC25B,LONRF2,FOXN3,KMT2C,DLGAP3,PLAA,CLCN3,NRXN1,QKI,IGLON5,CNN3,ARMC8,CABP1,LETMD1,COL11A2,SEC31B,CDC42BPB,C2CD2,HAPLN1,CSF1,RIMS4,CNTNAP2,ERC2,CTH,KIAA0513,LONRF1,LIN54,RIMS3,DGKG,DCC,ELMO1,MAGI2,KBTBD11,RAB39B,NR1D2,CDON,ARRDC4,DTNA,DYRK1A,E2F6,EDNRA,HIPK3,FEM1B,EFNA2,FAM13A,EBI3,MBNL2,EGR3,LPAR6,EIF5,ELAVL2,RGS17,EML1,PAN3,EN2,EPB41,EPB41L1,RCAN2,MTSS1L,EPS8,NCALD,CEP85L,DNAJC27,EYA1,F3,CACNG2,MED12L,KIAA1109,FGF1,FGF14,AMOTL2,PCYOX1,RGPD5,FOXO3,ANKFY1,NPTN,CELF1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,GAB1,GABRB1,GABRB3,CAB39,BRPF3,NEK6,GCNT2,MSTN,CSDC2,GK,GPR75,INSM2,KCNMB4,GPD2,B4GALNT4,ADAP1,CECR2,DIDO1,GRIK3,GRIN2D,GRM5,PTPRT,KIF3A,MFSD2A,FAM222A,HAS2,KLF12,MIER3,HMGCR,HNF4G,AGFG1,MSL1,IGF1,IL6ST,INPP1,DIPK1A,METTL21A,KCNA4,KCNA6,KCNC2,KCNJ3,KCNK2,KCNN3,KPNA5,LIFR,NCOA7,LSAMP,MAN2A2,MAPT,MARK1,AQP11,MATN3,MDFI,CHIC1,MDM4,MEF2C,MEIS2,KITLG,MITF,MMP16,MN1,MSI1,MDGA1,LAYN,MYT1,NCAM1,NCAM2,NF1,NFIA,NFE2L2,ALDH1L2,NOVA1,NRCAM,OPA1,OPHN1,PAX6,PCDH9,CDK18,PDE3A,PDE3B,PDGFRA,PDPK1,CDK14,CDIP1,POU3F2,PKIA,PRKCB,MAPK10,GRAMD1C,RELN,CNNM2,NKAIN1,MARCH1,FAM184A,RASGRF1,RET,FIGN,RFX3,C12orf49,ALG9,ROBO1,FBXW7,LGR4,HUNK,RXRA,FAM192A,CASC3,FAM102A,PPM1E,ARX,CPEB3,MAGI3,FNDC3A,CCDC92,FAM81A,PKNOX2,CPEB4,EPC1,RCOR3,MBD5,FAM126B,KDM4B,SCN3B,KIF21B,KDM3A,MYCBP2,PEG10,NPAS3,NFASC,C11orf87,ATP10B,CLSTN2,COLGALT2,LARP4,NXT2,MAPK8IP3,GSE1,FAM168A,ACSBG1,PRRC2C,ANKRD12,PDLIM2,KLHL4,SATB2,RPGRIP1L,RALYL,NSD1,CRTC1,GPRIN3,FRYL,GZF1,NACC2,CBX5,NR2C2,PRMT8,CADM1,GORASP1,FLRT2,PLEKHH2,BCL2L13,MICU3,CA10,MAP3K12,NAV2,MVB12B,FZD3,CERS6,ADAMTSL3,JMJD1C,ADAMTS10,FRMD6,NETO1,RNF146" MicroRNA hsa-miR-491-3p:mirSVR_lowEffct hsa-miR-491-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.24E-152 2.95E-148 1.38E-150 1.27E-149 377 1527 "TTYH1,SDE2,ACADM,CLK4,ARID1A,CSMD3,NDRG3,KLHL32,RNF157,AXIN2,SORCS1,PLEKHH1,BEND6,INTS2,ABCD2,ALK,DPP10,USP28,PHF12,PKP4,ANXA7,APBB2,MAGEE2,USP37,APP,CDC14B,MIER1,SLC7A14,PPP4R4,TMEM263,CASK,ZFYVE28,ARRB2,CDK13,ZBTB10,ATP2B1,SLC2A11,DPY19L3,DOCK11,ADGRB2,ADGRB3,MPDZ,SEC11C,BCHE,FUBP1,JAZF1,RAB29,CACNB4,CALB1,CAMK2D,CANX,CAST,LDB2,METTL6,FMNL3,CDC27,MAGI1,CLGN,FOXN3,SOCS6,CHN2,RAB28,NRXN3,FBXO7,C4orf33,TMEM184B,CNN3,CNTN1,PCYT1B,FAM149A,AKAP6,AKAP5,TBPL1,RBM39,GDA,SNCAIP,SIPA1L1,PDE4DIP,CNTNAP2,CTH,CFAP61,NRSN1,PUM1,PPP6R2,ST18,EDRF1,MYADM,KATNAL2,ZFYVE16,ZNF337,LONRF1,KIAA0586,KCTD8,IST1,PITPNC1,YTHDC1,C8orf34,FBXL5,COPS7A,FBXO25,DDX46,SPOCK3,RABGAP1L,MTX3,DLG3,NR1D2,DMTF1,CASP8AP2,FARSB,E2F5,E2F6,EBF1,EDNRA,KLHL5,SH3GLB1,TENM1,RGS17,COQ7,ENPP6,STX2,CEP85L,ETV1,GMPR2,ABCA8,WAC,TBC1D16,ACSL4,CEP78,SEC24B,MED12L,FGF13,POLK,SUCO,MEX3B,FOXG1,CAP2,IP6K2,SEMA4D,NELFCD,NBEA,HVCN1,NPTN,CSPG5,TBR1,SDCBP2,STAG2,MEGF11,DKK3,GABRG1,HBS1L,GALC,B4GALNT1,ERAP1,ATP8A2,KIAA1841,DNER,NEU3,NFU1,GLS,TOX3,KDM2B,RAB40B,GOLGB1,ADGRA3,GPD2,TDRKH,FUT10,GPR22,CNTRL,ATP2B1-AS1,RFFL,BTN2A1,WIF1,HAS2,HRH3,LINC01102,USP51,SMAP1,EID2B,C5orf24,NKD1,RBPJ,PLD5,IL12A,NME9,KCNA4,KCNA6,KCNB1,KCNH1,CLVS2,KCNK1,CREG2,IPO5,LAMP2,PAXBP1,ZFYVE27,MBD1,MBNL1,CHIC1,MDM4,LRP1B,SHC3,MEF2C,MGAT3,MIA2,COL28A1,N6AMT1,CTNNA3,MYO6,ZNF862,PABPC1L2A,BEX5,NASP,ZC3H12B,NDP,NEUROD1,ALDH1L2,CNOT4,NRCAM,SMIM11A,NTRK2,NUMA1,GPR88,PCSK1,PDE4D,CDK14,ANLN,ZFYVE21,PLP1,PCDH18,PDZRN4,SCHIP1,ING3,NXPH1,POU6F1,MED1,TATDN3,PPP2R5E,PPP3CB,RASGEF1B,RAB39A,SLC22A23,SYTL2,GON4L,CNTLN,ANKHD1,ELOVL2,PTPRB,PTPRD,EML5,PTPRG,FAM120C,PPP2R3C,PID1,PLEKHB2,RAD52,SH3TC2,ARID4A,DBX2,HKR1,VEPH1,KHDRBS2,REV3L,FIGN,ARHGEF10L,RIC8B,PBRM1,LGI2,CCDC82,TMLHE,CARF,ROBO1,NEK11,EPHA10,ACER3,LGR4,WLS,AMER2,FOXRED2,SEMA6D,SATB1,CSRNP3,SEC14L1,SUPT20H,ITSN1,SH3GL3,FERMT1,KIF16B,CPEB3,ANKRD6,PREX2,RAB3GAP1,SLC8A3,CCDC88A,SHANK2,BTBD7,TET1,ZFP1,RCOR3,MBD5,KDM4B,SCN3B,SOX1,SOX11,KDM3A,ENKUR,LHFPL4,MCF2L2,LMO3,SRPK2,ATP10B,ITPRID2,SSTR2,MPRIP,DIP2A,KANK1,AJAP1,FGD4,VPS13A,SYN2,TAC3,ATP11A,TACR1,ADGRL3,TBCEL,VWC2,TCF4,DMXL2,SATB2,TCF7L2,ZEB1,RPGRIP1L,RALYL,FRYL,DICER1,CRB1,ITGB3BP,AP4E1,TIAM1,CHST5,TRPS1,ZMYND8,TSN,RPL7L1,EIF4ENIF1,UBE2H,DNAJC12,OSBP2,MEAF6,RICTOR,XPO1,ZIC2,ZNF711,ZNF24,CFAP52,ZFP41,AGMO,PLPP4,LYPD6,CELF4,ZBTB38,TMEM237,ZNF184,SLC30A4,CADM2,RNF103,PCDH15,NAV3,TMEM163,C12orf4,PDSS2,PAK5,CERS6,FRMD6,NETO1,LAS1L,FAM198A" MicroRNA hsa-miR-211:mirSVR_highEffct hsa-miR-211:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.25E-152 2.95E-148 1.38E-150 1.27E-149 384 1584 "DPF1,TTYH1,SDE2,KCNH8,TKTL1,ARID1A,XKR4,NDRG3,KLHL32,SLITRK1,CCDC85A,GALNT13,ADD2,ADD3,CDC7,ADORA2A,PWWP2A,ESYT2,SLC44A5,AP2A2,INTS2,MTUS1,TAOK1,ADGRF5,C1QTNF3,SEMA6A,SPOP,ALCAM,BIN1,ZFAT,USP28,UPRT,ALS2,SEMA4G,TMEM263,SPTBN4,RGS20,MARCH3,DDX3Y,ATM,ATP2B1,TTLL9,SEC11C,RGS9,FGF17,C5,OSGIN2,CACNA1E,KALRN,CAMK2D,TRIM41,SYT6,CCNH,MTMR7,CDC27,CDC42,CDH2,LGI1,L3MBTL4,CFL2,SOCS6,CHN2,PLAA,CLU,TPP1,CLTC,NIPBL,ARMC8,AKAP6,COL4A5,SLC25A27,AHCTF1,BAG4,ZNF521,ZFP28,RBM39,HAPLN1,RNF14,GDA,TRIM69,FEZ1,SUSD5,VAC14-AS1,DZIP3,ERC2,CFAP61,NRSN1,RUBCN,CCDC144A,CYBB,BOC,HDAC9,GAPVD1,TCAF1,DCAF8,TOX,CENPL,LONRF1,DGKG,TMEM170A,DAPK1,DBI,SIRPA,ARMCX4,ARMCX2,DGCR5,ZEB2,TIAM2,FBXL5,DDX46,RHOBTB1,PLPPR4,SPOCK3,G3BP2,RABGAP1L,FAM107B,ZNF582-AS1,CHRDL1,GRIN3A,DMD,HS3ST2,DNM2,DMTF1,SLC12A6,PDCD6IP,RCAN1,DTNA,FRY,EFNB3,CELSR3,APH1A,KMT5B,RASA4,GOLGA7,ELAVL3,C8orf37,EPHB1,RABEPK,SRRM1,SIRPB1,WAC,RPS6KC1,ACSL4,SCML2,FER,KIAA1109,FGFR1,POLK,SUCO,CAP2,ATP13A4,SGIP1,SLC37A3,COQ5,NBEA,SMC2,USP16,RASL10A,NPTN,ATP6V1H,ZNF605,KHDRBS3,NSG2,NSG1,STAU2,B3GAT1,STAG2,GABRA2,GABRB1,GABRG1,GABRG2,HBS1L,AHCYL1,BRPF3,ARPP21,ZNF274,NEK6,ERAP1,C15orf41,LRRC37A6P,GCNT2,GDF9,PCDH17,GGT7,PPARGC1A,GLRB,TOX3,ZNF638,RAB40B,GPT2,ATF7,FUT10,RAPGEF4,GRIA2,GRIA4,NR3C1,MAP4K5,IRAK3,RASSF8,HAS2,HMGB1,GABARAPL2,HMX1,OPALIN,SMAP1,IRF8,LRRCC1,SCRT2,INSM1,JAK2,SLC35G1,OLFM3,KCNC2,KCND2,KCNK2,STXBP5,SYTL4,HECTD2,NCOA7,MAG,LOC100128239,ZFYVE27,MAT2A,MBNL1,MEIS1,MGAT3,MMP16,CD200,ERICH3,MRPL42,PABPC1L2A,NOVA1,LRIT2,NTRK2,OPHN1,SNTG1,PCDH9,PDE4A,PDE4B,PDE4D,BEST3,CDK14,TMIE,FAM218A,RETREG1,XRN1,GPSM2,SMIM7,LRP12,PRRX1,SEPT4,SLC36A4,POLR2F,POU3F2,MAPK9,VPS13C,GDPD2,SNRK,PIGG,SPDL1,PTPRD,EML5,PTPRE,C1orf109,PTX3,PID1,CEP97,TMEM255A,USP47,CCDC40,ZNF793,ZDHHC14,GTDC1,SEC61A2,RIC8B,ZFHX4,CARF,GSTCD,CCDC25,UEVLD,FBXW7,TCP11L1,KCNIP3,RXRG,TMEM156,AMER2,MIR124-2HG,ATXN2,SCN2A,FNIP1,ELMOD1,SELL,ASRGL1,ARX,FERMT1,KIF16B,SHC4,FHOD3,CTXN2,KANSL3,YPEL4,SLC8A3,BTBD7,SORCS3,MYH15,SMARCE1,RCOR3,MBD5,KIF13A,CMTR2,SNRPN,UNC80,MYT1L,TRERF1,ZCCHC24,MYCBP2,KDM4C,ZNF423,ZC3H13,SRPK2,ATP10B,SMOC1,ZC4H2,SS18,ZSCAN29,ELOVL4,RGL1,GANAB,FNDC9,SYPL1,TACC1,ANKRD12,PJA1,CAMTA1,DNMBP,TBCEL,TCF4,SATB2,ZEB1,TCF12,SZT2,SYNE1,FRYL,TEX15,SIRT1,GPR161,GZF1,TIE1,ZFP91,ERCC6L2,TMPO,NPL,TPM3,TRPC1,ZMYND8,ANO5,RPL7L1,AMOT,FLRT2,PLEKHH2,VSNL1,ZNF781,GUSBP1,XRCC4,CFAP298,MICU3,REEP1,TMEM237,EMSY,PRDM2,STOX2,PRDM8,TMEM178A,VPS35L,GAL3ST3,WNK3,PLSCR4,RGS7BP,DOCK8,ST7,FBXO36,RNF170,NETO1,JPH3" MicroRNA hsa-miR-367:mirSVR_lowEffct hsa-miR-367:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.96E-152 3.35E-148 1.56E-150 1.43E-149 407 1777 "VWA5B2,AS3MT,ADARB2,ELFN2,SLITRK1,CCDC85A,ADD3,ERMN,UNC5A,PWWP2A,BEND6,MTA3,HACE1,OSBPL6,OSBPL8,TAOK1,BCAR3,PCDH10,UNC79,AMPH,LRCH2,ANK2,PPFIA2,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APAF1,APBB2,MAGEE2,DDO,VAT1L,AQP4,PPP4R4,CASK,ARHGAP5,RGS20,CDK13,MARCH3,DACT3,NCOA1,ASTN1,ALDH4A1,SLC4A4,ATP1B3,DOCK11,BACH1,SNAI3-AS1,FUBP1,BSN,CDK5R2,BTRC,SLC16A4,TMEM257,CDC42,L3MBTL4,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,AKAP7,PCYT1B,ARMC8,BTF3L4,ABI3BP,COX4I1,AHCTF1,MYRIP,ZNF521,CHD1L,SEC31B,C2CD2,CREM,AKAP12,CLIP3,AATK,RGS6,ARHGEF10,MICAL2,SIPA1L1,PHACTR3,DZIP3,PPP6R2,CX3CR1,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,DGKB,SCRN1,BRINP1,GIT2,SIRPA,DCC,HP1BP3,KIAA0753,DDX46,SNAP91,NTM,WDR20,GRIN3A,NR1D2,DPP6,DPYSL2,ABI1,MAMLD1,EDIL3,SH3GLB1,EFNB3,FAM13A,PHF20L1,ABI2,EIF4G2,SORBS3,TENM1,STARD3NL,EIF1,EMX2,RCAN2,KCNMB2,SRRM1,EPS8,ERBB4,MRPL37,DNAJC27,EYA1,CLVS1,NSRP1,ZIC4,SCML2,DLC1,RACK1,FCGR1A,ST3GAL6,FKTN,ZSCAN30,TESK2,GORAB,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,UBE2E3,MEX3B,FOXG1,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,STAG2,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,MTHFD2,LRRC37A6P,KIAA1841,GATM,MSTN,ADAM28,PCDH17,DBF4,GLS,CBX1,DCLK2,PRRC2B,GPM6B,FUT10,EML4,GRIK2,GRM8,GSTT2,LINC01551,SOX21,GUCY1B1,IRAK3,ZHX1,HMGCR,ZNF491,NEGR1,TCEAL6,LRRC75A,EID2B,C5orf24,INSM1,ZNF385B,LRRTM3,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNK1,KCNMA1,KIF5C,IPO5,INSYN2,PAXBP1,HECTD2,FGFBP3,PACRG,C1orf194,MAP4,MARK3,TM6SF1,MEST,AFF1,MMP16,MXI1,MYH3,NEXMIF,BEX5,NEK1,NELL2,NFIA,NFIX,NKX2-2,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,GLIPR1L2,PCDH8,PCDH9,PCSK5,PDE4D,PIRT,PDGFRA,PDYN,PFKFB4,CDK14,FAM218A,XRN1,FAM216A,PCDH18,PMP22,SPATA6,EPB41L4B,PPARA,PPP2R5C,PPP2R5E,PPP3CB,RANBP3L,PRKAB2,PRKACB,PRKCG,PKN2,PRKCZ,EPDR1,DCHS2,LAMA1,MDGA2,CNTLN,ANKHD1,UHRF1BP1,OCIAD1,PTPRG,PEX2,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,SLC6A15,RET,GTDC1,RLBP1,SLC25A36,RPRD1A,ZFHX4,RERGL,EXD2,ALG9,ACER3,STK32B,LRRK2,LGR4,RPS20,SYNDIG1,RYR3,ZNF331,SEMA6D,CSRNP3,ATXN7,LINC00461,SCP2,RASA3,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,CHD9,SYBU,ANKRD6,ZNF365,SLC1A3,FAM81A,PPP4R3A,SLC6A1,SEPHS1,ATF7IP,SORCS3,SMARCD3,MBD5,LMBRD1,MYT1L,DOK5,CLUAP1,ENKUR,HECW1,ZNF423,TSPYL2,MCF2L2,RBM26,SRPK2,TAB2,EPB41L3,ZC4H2,SS18,ERBIN,SEPT8,DIP2A,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,DDHD2,DNMBP,KLHL4,TBX15,ATMIN,TCF4,SIN3B,DMXL2,ZEB1,TCF12,NAT16,RALYL,SLC19A3,SLC35G2,TEK,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TMOD1,CSMD1,TPD52,RGMB,PDSS1,STXBP4,TRPS1,TSC1,SSBP2,TMEFF2,CADM1,AMOT,PITPNB,PLEKHH2,XRCC4,ZNF28,ELFN1,NDRG4,SPHK2,REEP1,MEIS3,ZXDA,PRDM2,TMEM178A,KCNAB1,C12orf4,AMN1,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NHSL1,NETO1,SENP7" MicroRNA hsa-miR-935:mirSVR_lowEffct hsa-miR-935:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-151 6.49E-148 3.01E-150 2.77E-149 396 1687 "TTYH1,ABR,ACTN2,ARID1A,ADCY6,ADD2,ESYT2,BEND6,AP2A2,GPR158,HECW2,KCTD16,NME5,KIAA1324,SORCS2,WDR35,TXNDC16,HFM1,ALCAM,BCAR3,FAM135A,PITPNM2,LRCH2,ALS2,DDO,CACHD1,SHTN1,ARNTL,CAPRIN2,ZBTB10,ASTN1,ATP2B1,B3GALT2,LINC00847,SEC11C,BCHE,CFLAR,KSR1,SCAPER,WASF1,CA8,CA12,CALB1,SLC25A14,VXN,CAST,LRBA,CLGN,CACNA2D2,TAOK2,RAB28,ZFYVE9,QKI,MAP4K4,CNR1,CNTFR,AKAP6,SLC25A27,ZFP28,MFSD4A,SEC31B,RNF14,CS,ARHGEF10,ATRNL1,VCAN,PHACTR3,CTH,PUM1,ST18,RUBCN,CX3CR1,BOC,DOCK4,ARHGAP32,FGFR1OP2,GAPVD1,RIPOR2,HDAC4,TOX,LONRF1,MATR3,KCTD8,DGKB,TOMM20,IP6K1,PABPC5,BRINP1,AIF1L,GIT2,DCC,PITPNC1,ELMSAN1,ZBTB24,B3GAT3,CEP170,MAGI2,POM121,RHOBTB1,SV2B,SPOCK3,SRGAP3,AK5,WDR20,DLG3,DMTF1,CASP8AP2,DPP6,RCAN1,ECM2,E2F5,EDN1,ANKRD46,HIPK3,HEYL,FRY,APH1A,KMT5B,EGR3,EIF5,ELN,PAN3,EIF1,LRRC23,TMEM74,ACSL4,TAOK3,EFEMP1,FCGR1A,TOMM40L,SEC24B,MED12L,KIAA1109,FGF13,FGF14,SUCO,SEC23B,SYNCRIP,FLT1,NBEA,TMEM107,SMC2,PDLIM5,FAM49B,STAMBP,DACH2,B3GAT1,ZNF512,STAG2,GABRA2,GABRA5,GALNT15,GAD1,ZMYND11,ARPP21,DNER,MSTN,GFAP,RND1,DBF4,KDM2B,FERMT2,LILRB4,GPD2,ATF7,PCLO,RAPGEF4,RFFL,GRIK3,ATE1,PRDM5,LINC01102,MIER3,ELOVL5,SCRG1,SHISA6,FAM95B1,SOWAHA,IGFBP1,NKD1,DOCK7,IL11RA,BRINP3,INSM1,SLC35G1,KCNA4,KCNC2,KCNK1,KIF5A,KIT,LIFR,FGFBP3,MAOB,MATN3,MBD1,MBP,MID1,XRRA1,GIT1,COMMD5,THYN1,CTNNA3,MTTP,MTR,MYO7A,ZNF862,FXYD6,NAP1L3,SLCO1C1,NFIA,NFE2L2,DNHD1,OMG,P2RX7,DPY19L2P2,PDE3B,PDGFRA,ENPP2,GPR85,PFKFB2,PFKFB3,OLA1,SERPINI1,ANLN,NLE1,PLP1,PMP22,STRN3,LRP12,PRRX1,FAT3,NXPH1,MINDY2,PPM1B,PPP3CB,PRKACB,CEP41,MAPK4,MAPK9,MAPK10,APTX,SIDT1,SNRK,PLPPR1,BDNF-AS,STK32A,C1orf109,PEX2,PPP2R3C,FAT4,NWD1,KHDRBS2,REV3L,ERI2,FIGN,SEC61A2,SLC25A36,PBRM1,TMLHE,ALG9,PNMA8A,ROBO1,RPE65,SPIN3,MCMBP,ATP8B4,ADAL,CNTNAP3,LGR4,WLS,CLIP1,ZNF568,CCDC112,AP1AR,SEMA6D,SATB1,SCN2A,SLC30A10,PEAR1,SOX6,SUPT20H,ITSN1,PPP1R9A,AMBRA1,SLITRK3,NLGN1,CLSTN1,WDR37,SEPHS1,RADIL,SLC15A2,BTBD7,TET1,CPEB4,NAXD,SLN,TTC17,IFT122,SNAP25,TRERF1,FNBP1,KDM3A,SP4,ENKUR,ZNF423,KIF1B,MCF2L2,NPAS3,SRPK2,TAB2,PBLD,ITPRID2,SSTR2,SS18,SSPO,NXT2,ST5,ZSCAN29,SEPT8,NECAB1,ABCC8,VPS13A,ANKRD28,SYT4,DDHD2,CNTN2,ADGRL3,AGTPBP1,SATB2,TCF12,SZT2,SYNE1,DOCK9,ARHGEF12,SLC35G2,FRYL,TEX15,PMS2CL,CRB1,SLC44A1,MTMR14,HEY1,ZFP91,NR2E1,ERCC6L2,KCTD2,TPM1,TPM3,WBP2,CHST5,RGMB,SYNPO2,STXBP4,TRPS1,ZMYND8,DCBLD1,TMPRSS5,ANO5,CADM1,EIF4ENIF1,SLAIN1,MEAF6,VIPR2,VSNL1,P2RY12,NSD2,SF1,PCDH20,ZIC2,ZIC3,ZNF711,AGMO,SLC26A10,TMEM237,EML6,ANKS1B,ZFAND5,SMARCAD1,MAP3K12,LRP8,SLC38A1,TMEM178A,C12orf4,EPM2A,FAM13C,AMN1,DOCK8,UBE3B,JMJD1C,ZNF248,NHSL1,ZDHHC20,IFT88,SOCS4,SLC4A10,GAN" MicroRNA hsa-miR-137:mirSVR_highEffct hsa-miR-137:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.25E-151 7.01E-148 3.23E-150 2.97E-149 389 1629 "SERPINA3,KCNH8,ACADM,CLK4,ABHD6,NCKAP5,KDM5D,CSMD3,FMNL2,ADORA3,BEND6,DPY19L2P4,AP2A1,INTS2,MTUS1,NME5,C1QTNF3,ABCD2,PCDH10,UNC79,ANXA7,PARG,SHROOM2,AQP4,CADPS,MARCH3,ASPH,ATM,ATP2B2,SLC2A11,B3GALT2,DPY19L3,ADAM23,TTLL9,ADGRB3,DST,ARHGEF7,CACNA1G,CACNA1D,CH25H,MTMR7,TMEM257,DGKI,LRBA,DCLK1,TIGD7,CCPG1,CHN2,SYNPR,NRXN3,NRXN1,TJP2,QKI,NIPBL,ARMC8,FAM149A,COL4A5,BTF3L4,SLC4A7,ABI3BP,BAG4,ZNF385A,PNKD,GDA,RGS6,CSNK1G3,NCAN,GREB1,CFAP61,RIMS2,ST18,KATNAL2,ARHGAP24,HDAC4,ZFYVE16,TBC1D5,MAML1,DAPK1,ELMSAN1,ZNF804A,ZC3H11A,DDX46,RHOBTB1,CHRDL1,NR1D2,CPEB2,RCAN1,DTNA,DYRK1A,ABCC9,GOLT1B,E2F6,AASDH,EDIL3,SEZ6L2,EDN1,FAM135B,EDNRB,SGK2,FRY,RBM12,PHF20L1,MBNL2,AASS,KCTD3,PLEKHA1,RGS17,EML1,CALCRL,RCAN2,KCNMB2,SLC43A2,CEP85L,SRARP,ADGRV1,EZH1,FAM198B,FCGR1A,FCGR1B,TOMM40L,FER,KIAA1109,SCARA3,SYNCRIP,AGAP3,NBEA,TPK1,ATP2C1,ZNF605,DACH2,NRG3,ZNF512,PHYHIPL,MEGF11,DKK3,MEGF10,GABRA1,GABRB3,AHCYL1,ZMYND11,GART,WASHC2A,GPR162,PPARGC1A,MALT1,KIRREL3,GK,RAB30,GLS,ZNF638,LUZP2,GNAS,ADGRA3,GPD2,GPR34,ATP2B1-AS1,GRIA4,GRM1,GRM5,GRM7,RNF165,PTPN5,RABL2A,SOX21,RNFT2,MAP4K5,WIF1,MAEL,RASSF8,NXPH2,HLF,HAPLN2,TCEAL6,FAAP20,RBPJ,PLD5,SCIN,SCRT2,BRINP3,ZNF385B,KCNA2,KCND1,KCND2,KIT,LAMP2,MAP2,MARK1,LYPLAL1,MDM4,LRP1B,MEST,MITF,MKLN1,MOBP,MSI1,ADAM22,CTNNA3,PABPC1L2A,FXYD6,NCAM1,NCAM2,RCOR2,NEFH,NEUROD1,NEUROD2,NF1,SLCO1C1,OTOGL,CNOT4,NOVA1,NTRK3,GPR88,CHAMP1,LOC100128398,GPR137C,SNTG1,CNTN3,PBX1,ETFRF1,PCSK5,PDE1B,PDGFRA,GPR85,BEST3,RETREG1,XRN1,PLP1,PCDH18,HMGCLL1,STRN3,LRP12,ING3,SLC36A4,FAT3,MED1,LRRN3,PPP2R5E,PRKACB,RAB39A,PKN2,DIRAS2,GDPD1,WBP1L,MDGA2,WDR25,CNTLN,UHRF1BP1,ELOVL2,PTN,TMEM260,PTPRG,NKAIN1,STRC,ZNF844,RAD51D,ZNF793,OXR1,MSANTD2,RDX,ZMAT4,MORC4,GTDC1,UBR7,RGS3,RNASEL,TMLHE,RAVER2,PCMTD2,RPE65,FBXW7,ATP8B4,LRRK2,LGR4,SYNDIG1,ABCA11P,SCN2A,LRRTM4,IL17RB,SUPT20H,ITSN1,NTNG1,CHD9,BCAN,ZNF365,PPP4R3A,SLC6A8,SLC6A9,SLC8A1,SLC12A2,ATF7IP,GKAP1,SMARCE1,LIMCH1,RIMS1,FAM126B,USP33,SOX1,BDP1,NMNAT2,CLUAP1,ENKUR,ZC3H13,RBM26,C11orf87,TROVE2,SS18,ERBIN,NXT2,NEK4,DIP2A,FGD4,VPS13A,PLCB1,SYT1,COBL,ANKRD12,CAMTA1,KLHL4,ANO4,ACSL6,SATB2,RPGRIP1L,TCF12,WDR7,PCDHGA11,SYNE1,PCDHB9,PCDHB7,AHCYL2,TEX15,TEK,ZFPM2,ITGB3BP,AP4E1,HHIP,AKTIP,TJP1,DDHD1,TLR4,HEY2,TMPO,PRRT1,TNS1,C9orf85,RGMB,PDSS1,FNDC5,TSN,TUBB1,UBE2H,SLC35A4,SLAIN1,OSBP2,USP1,BCL2L13,VSNL1,WIPF1,WNT7A,RICTOR,KCNT2,TRIM9,MKRN3,EML6,ZSCAN26,ANKS1B,SH3GLB2,LAMP5,CA10,SLC30A4,EMSY,PRDM2,CIAPIN1,SLC17A6,MVB12B,PLSCR4,RGS7BP,FZD3,DOCK8,RTN4,HNRNPA3,PHTF2,TIGD6,RNF170,MSRB3,FRMD6,IFT88,DPF3,CBLN2,PRRT4" MicroRNA hsa-miR-3128:mirSVR_lowEffct hsa-miR-3128:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-151 8.07E-148 3.70E-150 3.41E-149 418 1876 "SDE2,DGCR6,KCNH8,SYN3,CLK4,KDM5D,NDRG3,ADCY2,ADCY6,ADD2,SLC12A5,PWWP2A,DPY19L2P4,NLGN4X,ZNF608,INTS2,GPR158,HECW2,OSBPL6,DISP3,TAOK1,ADGRF5,LTBP4,OGT,ANK3,CCDC146,PPFIA4,CNIH2,ANXA7,APBA2,APC,GPAM,KIAA1614,CASK,ASTN1,CCAR2,CHID1,EIF4G3,ATP2B2,ADAM15,SNAI3-AS1,LINC00847,BCHE,DNAJC27-AS1,ARHGEF7,LINC00906,MTMR3,NIPA1,CA12,CACNB4,CACNG1,CALB1,THSD7A,PTBP2,CAMK2A,VXN,SPAG9,LRBA,ARHGEF2,SEPT7,REPS2,ZBED1,LGI1,CCPG1,CRLF1,UBE2L6,NUMBL,ASIC3,CHN2,B4GALT6,NRXN3,NMT2,CLTA,FAM189A2,CNN3,CNR1,SUMF2,LETMD1,COX4I1,BAG4,MFSD4A,PNKD,CLOCK,TRIM69,FEZ1,SUSD5,PLCH2,NCAN,CNTNAP2,PLXNA4,KIAA0040,PHF14,NRSN1,GPSM1,CYBB,MYADM,RIPOR2,ARHGAP24,EARS2,TBC1D5,ARMCX2,YTHDC1,DGCR5,ZEB2,ZBTB24,ELMO1,HP1BP3,ALKBH8,RHOBTB1,PLPPR4,SV2B,SPOCK3,SGSM2,DLG2,DYNC1I1,NR1D2,ECM2,FAM78B,MAMLD1,KRBA2,E2F6,EDN1,EDNRA,EEF1A2,TMTC1,SIDT2,RBM12,YAF2,PHF20L1,EGFR,EGR3,EIF4G2,ELAVL3,RGS17,CALCRL,PAN3,DCTN4,USPL1,EPB41L2,RASGRP2,EPHA5,DENND4A,ZNF549,RASL12,ADGRV1,NRN1,FAM198B,CACNG3,TAOK3,DLC1,TOMM40L,ZSCAN30,KIAA1109,FGF12,AMOTL2,HPCAL4,CAP2,SYNCRIP,FOXM1,SLC37A3,NBEA,USP16,FAM49B,TRIM16,ATP6V1H,KHDRBS3,CELF1,CGREF1,ZNF512,AHCYL1,NCKAP1,ERAP1,C15orf41,DISC1,GFAP,FREM1,PCDH17,GLI2,TOX3,MSL3,ZNF638,KDM2B,HTATSF1,FERMT2,GPD1,GPD2,PRUNE2,GPM6B,GPR34,NUDT21,ADAMTS13,PRDM5,LINC01089,KIF3A,GYG1,WIF1,PADI2,PTGDR2,KLF12,HMGB1,HMGCR,HNMT,OPALIN,AGFG1,LRRC75A,IRF8,LINC00667,IGF1,IGSF1,SCIN,INPP5B,SLC6A17,SLC35G1,KCNA1,KCNK2,KCNN2,LAMP2,LIFR,SMAD1,ZFYVE27,MAP2,MAP6,MATN3,MBD1,MBNL1,IL17D,LRP1B,ERICH3,SAMD5,JAKMIP3,MSR1,MYO6,MYO9A,PABPC1L2A,NAP1L3,NCAM2,NEK1,NF1,NTRK2,IGSF11,CHAMP1,CLDN11,ZDHHC22,DPY19L2P2,PCDH8,PCMT1,PDE1C,PIRT,ENPP2,GPR85,CYTL1,OLA1,PIK3C2A,PRRX1,RETREG2,TNPO2,PPARA,PPM1B,PPP2R5E,RANBP3L,MAPK7,DIRAS2,WBP1L,PSMD13,PIGG,CNTLN,PTHLH,PTK2,EML5,TMEM145,ZNF615,TUG1,RASGRF1,RBBP6,MSANTD2,RDX,RET,REV3L,ERI2,GTDC1,RFX5,RGS12,SEC61A2,RNH1,LGI2,TMLHE,GSTCD,ROBO2,SPIN3,PTGR2,PAQR6,MEG3,KCNIP2,NCBP3,TRAPPC13,RMI1,DGLUCY,SEMA6D,LRFN5,TNFRSF19,SOX6,GALNT10,SCAF8,ASAP3,SHC4,HKDC1,ST6GAL1,CNKSR2,DZIP1,FAM81A,RPH3A,PPP4R3A,FAM214B,SLC6A1,KANSL3,SLC8A3,BTBD7,NAXD,SLN,DMRTC1,IFT122,RIMS1,MBD5,SNRPN,PALLD,TMCC1,FAM126B,PDZRN3,MYO16,PDZD2,TRERF1,SOX2,SOX5,BDP1,ZSWIM8,IDI2-AS1,SPTAN1,KIF1B,SPART,POGZ,ZNF302,SAMSN1,SSTR1,NKAIN2,SEPT8,TTBK2,KANK1,SYT11,ZFR2,RHBDL3,ASTN2,TACC1,TACR1,TAL1,ADGRL3,ANO4,DMXL2,TCF12,SYNE1,DOCK9,PHF24,TMEM151B,GPRIN3,AHCYL2,TEX15,SIK3,CYB561A3,RNF216P1,SIRT1,ZFPM2,CRB1,AKTIP,ARL10,MTMR14,BHLHB9,ERCC6L2,KCTD2,CSMD1,NR2C2,SYNPO2,TRIO,NEIL2,TSN,TUBB1,DNAJC12,SLAIN1,PLPPR2,NSD2,XRCC4,SF1,ZNF708,TRIM9,MKRN3,SPHK2,TCEAL7,ZNF154,REEP1,ANKS1B,SMARCAD1,WNK1,PRDM8,XKR7,KCNAB1,TRIM16L,MVB12B,DOCK8,RTN4,UBE3B,HNRNPA3,NUP214,ACTR3B,FAM219B,TRAM2-AS1,TIGD6,SNX14,FXR1,GAN,JPH3" MicroRNA hsa-miR-190b:mirSVR_lowEffct hsa-miR-190b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-151 1.03E-147 4.70E-150 4.33E-149 390 1639 "ACADM,CLK4,NBAT1,ACTN1,CSMD3,ADAR,ADCY2,KLRC4,CCDC85A,ADD2,PLEKHH1,PWWP2A,GPR158,HECW2,RTL9,HACE1,WDR35,SPARCL1,PCDH10,BBOX1,ANK3,SEMA7A,MAP4K3,ANXA7,PARG,APP,ASPA,ASPH,NUMB,TMEM108,ATM,ZNF582,NOL4,DPY19L3,BBS2,BCHE,MIR9-3HG,DCAF5,KSR1,FUBP1,C5,RAB29,LDLRAD4,CACNB4,KALRN,CAST,CBLN1,SHISA7,CCNH,RGN,MTMR7,P2RX6,LRBA,DCLK1,LGI1,NUMBL,SRSF11,CHGA,CHGB,SOCS6,CHN1,SYNPR,B4GALT6,RAB33A,CLCN4,NMT2,MAP4K4,NIPBL,CNR1,CNTN1,AKAP7,IQCK,COL4A5,BAG4,ZFP28,CREB5,SNCAIP,RGS6,ATRNL1,VAC14-AS1,FAM169A,SDC3,UBXN2A,CTH,PUM1,MYADM,SNPH,FRMPD4,ZNF337,RASSF2,LONRF1,MATR3,KCTD8,DAPK1,ARMCX4,ARMCX2,ELMSAN1,JAKMIP2,C8orf34,HEPH,HP1BP3,KIAA0319,CEP170,SACS,NTM,MTX3,DNM2,DOCK2,DUSP9,DNM1L,GOLT1B,FAM135B,ANKRD46,SYT15,KLHL5,TMTC1,MBNL2,KMT5B,EGR3,TENM1,STARD3NL,C8orf37,EIF1,VPS13B,EPB41,LRRC17,EPHA5,KCNMB2,EPS8,DENND4A,ADGRV1,EYA1,CACNG2,TUBA1B,ATP8A1,GTF2IRD2,FGF13,SCARA3,IP6K2,RGPD5,FOXO3,SLC37A3,NOP56,SMC2,PDLIM5,STAMBP,ERGIC3,MPP6,MEGF11,GABRA2,HRASLS5,GABRB1,GABRB3,HBS1L,ERAP1,ZNF559,DISC1,LRRC37A6P,MYOZ2,MMADHC,TCERG1,COPS8,HPGDS,GLRB,FUT10,LILRA1,GPR19,CECR2,GRIA1,GRIN1,NR3C1,GRM7,RNF165,GUCY1A1,MAEL,RASSF8,BACH2,SYNPO,LRRC75A,LIX1,DIPK1A,ZNF385B,KCND2,KCNJ3,KCNJ10,KCNK1,KIF5A,KIT,A1BG-AS1,MAN2A2,MAT2A,TM6SF1,MEF2C,MGAT3,KITLG,MOBP,CPNE9,SAMD5,JAKMIP3,NRBP2,CTNNA3,LAYN,NAP1L2,NCAM1,NEK1,SLCO1C1,NHLH1,CNOT4,SLC11A2,SETD4,GPR88,OLR1,OMG,LOC100128398,P2RX7,DPY19L2P2,PCSK1,PDE4D,PIRT,PDGFRA,ENPP2,ZDHHC8,SSH1,PIK3CD,ZNF655,SNX10,RETREG1,XRN1,FTO,MTRF1L,PURG,PMP22,EXOSC10,SDK2,NXPH1,POU3F2,PPP3CB,KANSL1,RASGEF1B,PRKCB,PLPPR1,UHRF1BP1,MTMR10,PTPRE,PTX3,PEX5,ZSCAN2,TUG1,CEP97,PLEKHB2,ZCWPW1,RASGRF2,FEZF2,RBBP6,HKR1,SLC6A15,DPF2,RGS7,RGS12,TTLL7,CCDC82,ROBO1,ROBO2,SGSM1,PRR5L,ACER3,LRRK2,AP1AR,CSRNP3,ATXN1,SCP2,ELMOD1,SLC30A10,MRAS,SCAF8,SGK1,CPEB3,DOCK10,NTNG1,MAGI3,CHD9,ST6GAL1,SLITRK3,ST3GAL3,SEC31A,SLA,SLC1A3,FAM81A,RUFY2,SLC6A1,SLC8A1,SLC8A3,SHANK2,NAPB,SLCO1A2,SLC22A4,SLIT1,CPEB4,MAST1,SORCS3,SMARCE1,ANKRD36,SNRPN,FAM126B,DOP1A,SOX5,BDP1,ZHX3,UHRF1BP1L,KIF1B,C11orf87,CLASP2,ITPRID2,STOX1,SAMSN1,SSTR1,LARP4,MAPK8IP3,ELOVL4,DIP2A,AJAP1,PRRC2C,VPS13A,SYPL1,SYT1,COBL,PJA1,FAM208A,ADGRL3,KIAA1107,TBL1X,ATMIN,TCEA1,VWC2,TCF4,DMXL2,TRIM2,WDR7,SYNE1,RALYL,ARHGEF12,TNS2,DICER1,ZFPM2,C18orf54,HHIP,DDHD1,KAT6B,TP53BP2,TPM1,NPL,TRIO,PDSS1,TRPS1,TUB,TMEFF2,ZNF610,FAM155A,EIF4ENIF1,UBE3A,BCL2L13,MEAF6,CCDC14,VSNL1,SLC13A3,XPO1,XRCC4,SF1,PCDH20,KCNT2,NDRG4,LYPD6,DHX33,MAP3K12,CADM2,LRP8,EVI5,PRDM8,SCG2,LINC00632,MPPE1,DOCK8,RTN4,JMJD1C,SLC39A12,KLHDC1,FXR1,NETO1,SLC4A10,GAN" MicroRNA hsa-miR-548u:mirSVR_highEffct hsa-miR-548u:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-151 1.22E-147 5.56E-150 5.12E-149 403 1749 "ACADM,NDRG3,ADD2,ADD3,SORCS1,PWWP2A,KIAA1211,PTCHD1,ZNF608,MTUS1,SNX32,KLHL13,KCTD16,KIAA1324,TAOK1,C1QTNF3,LRRC7,MARCH4,FAM135A,AMPH,OGT,PPFIA1,APBA2,UPRT,ALS2,LRRC4C,CDC14B,MIER1,TMEM263,TMEFF1,CDK13,MARK4,CAPRIN2,ASPH,CHRD,SLC4A4,ATP2B1,NOL4,DPY19L3,ADGRB3,DST,SYNJ2,IL33,CACNA1E,CACNB4,THSD7A,CALM1,TRIM41,CANX,SYT6,RUNX1T1,TMEM257,C1orf52,LRBA,CDC27,MAGI1,CCPG1,DIS3L,CHGB,CHN2,CASC2,MS4A7,SYNPR,QKI,TMEM184B,NIPBL,ARHGEF6,CNR1,AKAP5,TBPL1,HS3ST5,SEC31B,CDC42BPB,PREPL,CRY2,NCOR1,ABCG1,OSBPL3,CSNK1G3,ATRNL1,SIPA1L1,RIMS4,PDE4DIP,CTNND2,NOS1AP,CYBB,HDAC9,GAPVD1,RIPOR2,ZFYVE16,EARS2,IST1,DGKB,TMEM170A,DNAJC6,DCT,ZEB2,CNIH3,MAGI2,TMEM130,ZC3H11A,PLPPR4,SACS,G3BP2,RABGAP1L,CHRDL1,DLG2,DMD,NR1D2,ABI1,DTNA,DNAJB6,EDNRA,ANKRD46,SYT15,KLHL5,FRY,FSD1L,RBM12,YAF2,PHF20L1,MBNL2,KMT5B,LPAR6,KCTD3,EIF4G2,EIF5,COPS4,ELAVL2,PAN3,EPB41L2,RTN3,EXTL2,EYA1,FABP7,SCML2,CEP78,TOMM40L,GORAB,SEC24B,OLFM1,FGFR1,PRKAG2,POLK,IP6K2,FOXM1,UFM1,ATP6V1H,KHDRBS3,ST6GALNAC3,STAU2,SARAF,NRG3,OGA,FYB1,ERAP1,WASF3,KIAA1841,MYOZ2,GATM,IGSF5,WASHC2A,ADAM28,PPARGC1A,BRD8,GK,GLI2,RAB30,GLS,GNAL,PRRC2B,PRUNE2,GPM6A,TDRKH,GRIA4,GRIK1,ZBTB49,MAP4K5,HAS2,NXPH2,HLF,HTR2A,IFI16,ZIC5,KCNA2,OLFM3,KCNA4,KCNC2,KCND2,CREG2,STXBP5,LAMA2,SMAD1,PIK3AP1,MARK1,MAT2A,SYT9,IL17D,MEF2C,POC1B,MITF,ZNF680,BLOC1S2,ZNF92,NAP1L2,NCAM1,NCAM2,NELL1,NEK1,NEUROD1,NF1,NTRK2,GPR88,CHAMP1,OLR1,GPR137C,PAK3,CNTN3,PCSK1,PDE4B,PDGFRA,GNG2,PENK,CDK14,NLGN3,PIK3C2A,ZNF655,FAM218A,SNX10,PLP1,PMP22,STRN3,PRRX1,ING3,EPB41L4B,POU3F2,CRLS1,PPP3CB,PKIA,MAPK9,GRAMD1C,VPS13C,MDGA2,QRICH1,WDR25,PIGG,CNTLN,PTCH1,ANKHD1,PLPPR1,PTPRD,PTPRE,PTPRO,PPP2R3C,TMEM255A,USP47,FAM184A,RAP1GDS1,ENOX1,RADX,SLC6A15,ERI2,GTDC1,RFX3,PNMA8A,RPE,UEVLD,TCP11L1,LRRK2,LGR4,MEG3,SOX8,CLIP1,RTN1,ZNF331,RMI1,AMER2,SCN2A,SCN7A,SMPD3,SEC14L1,MRAS,ITSN1,ARX,SHC4,MAGI3,FBXO11,FNDC3A,R3HDM2,SLITRK3,NLGN1,EPN2,KANSL3,ZNF430,YPEL4,SEPHS1,CCDC88A,SPHKAP,SLIT1,SLN,ZNF667,COA1,KIF13A,SNRPN,USP33,SOX2,TNIK,BDP1,SP4,ZC3H13,NPAS3,SPART,SRPK2,SMOC1,ZC4H2,NKAIN2,ERBIN,NXT2,MPRIP,ZSCAN29,SEPT8,TTBK2,DIP2A,AJAP1,FAM168A,VPS13A,NUDT10,COBL,C12orf76,CAMSAP2,FAM208A,KIAA1107,TBCEL,FBXW11,ATMIN,ACSL6,DMXL2,CUX2,TCF7,TCF7L2,TRIM2,TCF12,WASHC4,SYNE1,DOCK9,PCDHB7,PUM2,USP32P1,TEX15,SIRT1,AP4E1,TGFBR3,MTMR14,TK2,NR2E1,ERCC6L2,HEY2,TMOD1,C5orf64,RBFOX2,C9orf85,METTL3,STXBP4,ZMYND8,TSC1,TTTY15,RFTN2,SGK3,RPRM,FAM155A,AMOT,FRRS1L,PLEKHH2,MEAF6,CCDC14,WIPF1,NPDC1,ZIC2,ZNF17,ZNF19,KCNT2,FSTL5,DHX33,WNK1,EMSY,PRTFDC1,ADAMTS9,NAV3,FIP1L1,RGS7BP,RTN4,PHTF2,ADAMTSL3,NHSL1,SNX14,FXR1,FRMD6,IFT88,NETO1,RNF146,SLC4A10,GAN,LAS1L" MicroRNA hsa-miR-532-3p:mirSVR_lowEffct hsa-miR-532-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-151 1.23E-147 5.57E-150 5.13E-149 422 1913 "ASPHD1,ACADM,SYS1,ACTN1,FMNL2,KLHL32,PNMA8B,ADORA1,ADORA3,RNF150,LRFN2,MTA3,PCDH10,PDZD4,AMPD2,KIF6,AMT,OGT,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,CNTNAP1,EPB41L5,GPAM,ALS2,APP,LGR5,MADD,MARK4,ALDH4A1,ZNF583,SLC2A11,TTLL9,AZGP1,CFLAR,BMP7,FUBP1,MTMR2,GYG2,CACNA1G,NIPA1,MYRF,DDR1,CACNB2,KALRN,PTBP2,NGB,CAMK2B,TRIM41,VXN,CAST,HIP1R,ARHGEF25,CBLN1,KRIT1,METTL6,P2RX6,CDC25B,CDH8,ZMYM4,LGI1,MAGI1,UBE2L6,CHRM1,CASC2,IGFBP7-AS1,ZFYVE9,PPT2,NRXN2,NMT2,ABCG2,DNAJB5,MAP4K4,LY86,IQCK,LETMD1,COX4I1,MFSD4A,HS3ST5,RNF14,ABCG1,SNCAIP,FEZ2,FEZ1,ARHGEF10,SIPA1L1,PDE4DIP,CTH,GREB1,CTNND2,NRSN1,RUBCN,ECE2,CYBB,ARHGAP24,DCAF8,PHF19,RASSF2,RIMS3,KCTD8,INTS1,SCRN1,SPOCK2,CTIF,ARMCX4,CNIH3,FBXL5,KIAA0753,RUSC2,COPS7A,C2CD2L,KIAA0319,GUCD1,SRGAP3,G3BP2,WDR20,ARNT2,SEC16A,HS3ST4,USP3,CDON,DMTF1,ACOT8,DRP2,ARRDC4,DTNA,FARSB,EBF1,EDN3,EDNRA,EDNRB,CNNM1,EFNB3,GPR61,MRO,MBNL2,ING4,C3orf18,DCTN4,ENO2,MFSD10,COQ7,LRRC17,SRRM1,DENND4A,ZNF391,CDHR1,ETV1,SIRPB1,MRVI1,EZH1,NRN1,CLVS1,CACNG2,CEP78,FGF1,FGF14,CAMSAP1,SUCO,IP6K2,VTI1B,FOXM1,SEMA6C,FLT1,ANKFY1,ZNF605,NSG2,CGREF1,ZMAT1,GABBR1,HRASLS5,GABRA3,GAD1,HBS1L,AHCYL1,ARPP21,ERAP1,SIGLEC8,C15orf41,ATP8A2,LRRC37A6P,ARFIP1,GFAP,USP19,HEPN1,DHRS4,CRCP,TNRC6A,GNAS,LILRB4,DIPK1C,ADAMTS13,NR3C1,LINC00839,RNF165,TMEM25,GSTM5,RABL2A,LINGO1,PSIP1,TMEM179,RASSF8,HPS5,TOX2,PADI2,NXPH2,KLF12,TNFAIP8L3,ARHGAP36,ELOVL5,HMGB1,HPCA,CPT1C,HSD17B1,SMAP1,MSL1,DOCK7,ZNF678,LRRTM3,KCND1,KCNJ11,MBP,MDM4,MEIS1,MMP16,MOBP,CD200,MRPL42,MSRA,MT3,C10orf105,MYO9A,RTL5,NBL1,NCAM1,NEFM,NELL2,NF1,NFYA,DNHD1,NUCB2,IGSF11,OPRL1,ZDHHC22,SNTG1,PDE2A,PDE4A,PDYN,ZDHHC8,NALCN,CAMKV,ZFYVE21,GPSM2,HMGCLL1,PLXNB3,C11orf49,TRHDE,STRN3,LRP12,EXOSC10,SEPT4,POLR2F,MED1,PPP1R1A,CCDC144B,PTPA,VSTM2L,PRKAR1B,MAPK3,MAPK4,DCHS2,MASP1,NDUFS7,GON4L,PIGG,CNTLN,NCR3LG1,BDNF-AS,ELOVL2,TMEM260,STK32A,OCIAD1,PTPRG,PEX5,ZSCAN2,PID1,RAD52,RALGDS,SH3TC2,ATG16L1,RAP1GAP,BSDC1,GAL3ST4,DPF2,RFX3,RFX4,RGS3,ARHGEF10L,KIF7,KLHL11,SUGCT,C12orf49,GSTCD,CYB561D1,ROBO2,RORB,PCMTD2,TMEM100,ZC3H14,PRR5L,RPS6KA2,LGR4,RTKN,KCNIP2,ZNF331,TMEM156,ATXN7,SCN8A,PRCD,ASIC4,TRIM46,GALNT10,STUM,ASRGL1,ZFP30,ITSN1,FRMPD1,MYO18A,SHC4,ST6GAL1,ANKRD6,PAAF1,ZNF365,SLC1A3,SLC1A6,SLC1A7,FAM214B,PKNOX2,SLC6A9,YPEL4,RADIL,ARHGEF40,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,CDK5RAP2,KIF13A,SNRPN,UNC80,WDTC1,NMNAT2,CLUAP1,IQSEC2,SPART,LHPP,STOX1,DIP2A,STAC2,NSFL1C,JMJD6,SYN2,SYP,POPDC3,TACC1,MTCL1,MLST8,DNMBP,PDLIM2,ALG1,TMEM136,ZEB1,WDR7,SLC19A3,ARHGEF12,FRYL,AHCYL2,DICER1,DICER1-AS1,AP4E1,ZNF106,THRA,TMEM9,TLL2,ZFP91,C5orf64,TNR,TP53BP1,TPD52L2,NPL,CHST5,ZNF384,DCBLD1,SSBP2,ZKSCAN5,UBE2H,UBTF,UCHL1,GORASP1,USP1,PLPPR2,VAV2,BEST1,NSD2,CLDND1,LGI4,TRIM9,FMN2,ZNF74,POLR3H,PCBP1-AS1,EMSY,LMAN2L,VPS35L,SEMA3B,PCBP4,PARP11,HRASLS,FAM219B,ZNF248,LAS1L,PRRT4" MicroRNA hsa-miR-221:mirSVR_lowEffct hsa-miR-221:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.79E-151 1.57E-147 7.07E-150 6.51E-149 376 1526 "CPNE2,NCKAP5,SYS1,TMEM132B,TMCC3,ADD2,ADD3,PTCHD1,BEND6,OSBPL8,CC2D2A,LRRC7,CEP126,BBOX1,LRCH2,SEMA7A,LCORL,USP28,PHF12,PKP4,GPAM,SHTN1,TMEFF1,STK33,ASTN1,INSYN2B,ATP1A1,SLC4A4,KSR1,SYNJ1,ARHGEF7,LINC00906,SCAPER,GYG2,NIPA1,OSGIN2,BTRC,CALM1,AIFM1,CD38,CDH2,LARGE1,CHGB,CHM,CHN2,CASC2,SYNPR,NRXN3,NRXN1,FBXO7,CNN3,FAM149A,AKAP6,ABI3BP,SMARCAL1,ZNF521,CNRIP1,MFSD4A,CP,ZNF385A,CPS1,RBM39,CRHBP,CRY2,ANKRD44,NCOR1,GDA,CSF1,ARHGEF10,OSBPL3,SUSD5,ATRNL1,SOCS5,SLITRK5,UBXN2A,PLCXD3,CFAP61,CTNND2,NRSN1,MATR3,RIMS3,MAML1,BRINP1,YTHDC1,C8orf34,DGCR5,KIAA0319,CEP170,DDX46,SGSM2,DLG2,DLX1,DYNC1I1,CDON,DMTF1,CASP8AP2,ATN1,DNAJB6,DNM1L,E2F5,WDPCP,HIPK3,RASGRP1,KLHL5,YAF2,FAM13A,EIF5,EIF1,KCNMB2,STX2,ERBB4,DENND4A,RTN3,RRAGB,EZH1,F3,FAM198B,TMEM132C,ATP8A1,CEP78,FKTN,STRADA,GTF2IRD2,FGF14,SCARA3,UBE2E3,MEX3B,FOXG1,SYNCRIP,FLT1,SLC37A3,STAMBP,ATP2C1,CGREF1,GABRB1,GABRG1,WASF3,IGSF5,RUNDC3A,TCERG1,RNPS1,GLRB,TNRC6A,PCDH11X,ZNF638,GNAO1,PRRC2B,PRUNE2,ATF7,GPR12,NUDT21,GRB10,PLCD4,GRM1,CIT,RNF165,TMEM25,LINC01551,WIF1,ZHX1,FRMD5,KLF12,HNF4G,HNRNPK,ZDHHC15,NEGR1,OPALIN,AGFG1,SHISA6,IGF1,C5orf24,DOCK7,USP54,RIPPLY2,ZNF385B,METTL21A,KCNC2,KCNJ16,KCNMA1,KCNQ3,CREG2,IPO5,CYP27C1,MAP6,ADAM11,MDM4,MEF2C,MEST,KCTD6,MID1,MITF,AFF1,MMP16,MOBP,ERICH3,COL28A1,SCG3,MTTP,ZNF862,NAP1L1,NCAM1,SLCO1C1,CNOT4,NRCAM,NTRK2,NUMA1,ZNF713,PBX1,DPY19L2P2,ETFRF1,PCDH8,PCDH9,PCSK1,PDGFRA,OLA1,CDK14,PIK3R1,ZNF655,CCSER2,HMGCLL1,PRIMPOL,LRP12,POU3F2,PPP2R5C,KANSL1,PRKAB2,HYDIN,DIRAS2,GDPD1,CNTLN,PTK2,PTPRB,OCIAD1,C1orf109,PTPRZ1,PTX3,TUG1,RAB3A,PID1,USP47,ENOX1,RBBP6,RBBP8,BSDC1,MSANTD2,SLC6A15,REV3L,GTDC1,FIGN,RFX2,RGS12,LGI2,TMLHE,C12orf49,NEK11,LGR4,RTN1,SEMA6D,SATB1,ATXN1,ASIC4,SELL,FOXRED1,KIF21A,ITSN1,ST6GAL1,SLITRK3,ST8SIA1,PAAF1,ZNF365,FAM81A,RPH3A,SLC6A11,SEPHS1,SLC11A1,SLC20A2,ATF7IP,SLN,SMARCE1,ANKRD36,SNAP25,SNCB,KIF13A,SNRPN,MYO16,UNC80,USP33,SOX1,BDP1,SOX11,KDM3A,SPP1,IDI2-AS1,CDK19,SRPK2,PBLD,CLASP2,ITPRID2,NEK4,SEPT8,RGL1,STX1A,SULF2,AJAP1,GSE1,FNDC9,C3orf70,PLCB1,SYPL1,SYT1,COBL,TACC1,TACR1,ANKRD12,DNMBP,ADGRL3,KLHL4,EHBP1,CUX2,TCF7L2,TRIM2,NAT16,GPRIN3,FRYL,CCDC173,SIK3,RNF216P1,PMS2CL,DICER1,SIRT1,CRB1,C18orf54,GPR161,GZF1,TIAM1,KCTD2,CSMD1,KAT6B,TRPC1,FNDC5,TTPA,TUB,AMOT,UGT8,PITPNB,ZNF781,NSD2,CLDND1,XRCC4,ZBTB14,ZNF74,TMEM237,AMZ1,ANKS1B,SPIRE1,PLPPR5,ZFAND5,PMEPA1,EMSY,MFF,LRP8,STOX2,PRDM10,ADAMTS9,PCDH15,FAM47E,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,FAM219B,RSPRY1,TRAM2-AS1,SOCS4,SENP7" MicroRNA hsa-miR-152:mirSVR_lowEffct hsa-miR-152:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.57E-151 2.01E-147 8.99E-150 8.28E-149 408 1794 "ABCF1,KCNH8,ASIC1,ACHE,NCKAP5,CSMD2,ADARB2,ADCY2,ADD2,PNMA8B,PLEKHH1,GRAMD1B,USP31,PWWP2A,ESYT2,DPY19L2P4,MTA3,SLC24A4,OSBPL1A,CC2D2A,HFM1,LRRC7,SPOP,SRPX,ARHGAP20,GOLGA7B,SYT13,MRTFA,AMPD2,KIF6,ZFAT,OGT,ANK2,CCDC146,USP28,KCNAB2,EPB41L5,ALS2,TNRC6C,SHTN1,SLC7A14,PDXK,LINC00173,CDK13,MARCH3,CAPRIN2,NUMB,ASTN1,ATP2A2,ATP2B3,MTMR9,BACH1,MPDZ,BCL2L2,KSR1,SYNJ2,LINC00906,MTMR2,CALM1,KALRN,CAMK2A,USP2,P2RX6,CD81,SEPT7,CDC25B,TIGD7,TBRG4,KMT2C,ZFYVE9,CLCN3,KIAA1549L,CLTC,FBXO7,FAM189A2,TJP2,FADS2,NIPBL,CNR1,IQCK,PCYT1B,LETMD1,ABI3BP,SLC35F1,CRY2,CSF1,PLXNA4,PPP1R16B,APPL1,PHF14,RIMS2,DCAF4,CCDC144A,KATNAL2,DCAF8,TBC1D5,IST1,ARMCX4,ARMCX2,SPATA2,HEPH,ELMO1,HP1BP3,CEP170,RHOBTB1,G3BP2,USP3,DNAH9,CDON,DOCK2,DMTF1,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,DYRK1A,ABCC5,SNX29,WDPCP,EDNRA,EDNRB,HEYL,EGFR,KMT5B,RASA4,AASS,EIF4G2,PAN3,EPB41,EPB41L2,RASGRP2,MTSS1L,GPHN,SLC43A2,STX2,EFS,TAOK3,SCML2,ATP8A1,ST3GAL6,FCGRT,AMOTL2,SCARA3,SEC23B,FOXF2,NBEA,TACC2,PDLIM5,ATP2C1,ZNF605,CGREF1,GABRB1,GALNT15,GABRG1,GALC,SIGLEC8,DISC1,SEPT9,ALDH1L1,TUBGCP4,SPIN1,GLS,TOX3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,RAPGEF4,TPPP,ADAMTS13,SERP2,GRM2,ZNF496,LINC01089,FAM19A2,TMEM25,RASSF8,FRMD3,ARHGAP19,HLF,SYNPO,HNMT,TLX1,AGFG1,HSP90AA1,HTR5A,ZNF546,IGF1,C5orf24,JAK1,SLC35G1,KCNH1,KCNJ16,KCNK1,KLRC2,VWA5A,PIK3AP1,MAN2A2,ZFYVE27,MAP4,AQP11,MBD1,MBNL1,MBP,SYT9,CHIC1,MDM4,MEIS1,MKLN1,MMP16,ERICH3,MSR1,PTOV1,MYO6,NEXMIF,NACA,NAP1L1,NCAM1,NELL2,NFYA,NOVA1,NTRK2,NUMA1,TBC1D25,OPA1,OPCML,OPHN1,ZNF713,P2RX7,GPR137C,ZDHHC22,SNTG1,DPY19L2P2,PCSK5,PRTG,PDE2A,PDE3B,PDE4B,PDE4D,PDGFRA,PIK3R1,CCSER2,SNX10,ZFYVE21,GPSM2,NLE1,FTO,MTRF1L,PRIMPOL,PMP2,LRP12,ING3,SH3KBP1,MED1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,EPDR1,HYDIN,MASP1,SLC22A23,SNRK,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,PLEKHB2,ATG16L1,ROGDI,RBBP8,PRRT2,RFX3,KLHL11,SEC61A2,RIC8B,ZNF532,CARF,TMEM206,RPL15,UEVLD,BAALC,ZC3H14,EMID1,RTKN,CLIP1,RTN1,SEMA6D,SATB1,CSRNP3,SCN2B,PRCD,SELL,MRAS,SUPT20H,RASA3,PPP1R9A,AMBRA1,FNDC3A,SLITRK3,SYBU,SLA,EPN2,KANSL3,PKNOX2,SLC8A1,CCDC88A,TRIM67,ATF7IP,CPEB4,RCOR3,SNAP25,SNCA,KIF13A,FAM126B,MYO16,UNC80,PDZD2,EMC1,KDM4C,TEX2,SPTB,CLASP2,CLSTN2,ERBIN,INKA2,STAU1,DIP2A,STXBP1,AJAP1,PRRC2C,C3orf70,PLCB1,TMEM150C,SYT1,C12orf76,CAMTA1,TAF9,EXOC7,AGTPBP1,FBXW11,TMEM136,TCF4,ZFP90,TCF7,WDR7,DOCK9,PHF24,PCDHB4,ARHGEF12,GPRIN3,HHIP,GZF1,MTMR14,NR2E1,HEY2,R3HDM1,C5orf64,RBFOX2,CDK20,CHST5,RGMB,METTL3,TRPS1,ZMYND8,HIRA,UGT8,SLAIN1,OSBP2,ZNF709,VAV2,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,SLC26A10,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,PRDM2,SLC38A1,RGMA,XKR7,HPS4,SNX27,KCNAB1,FAM47E,WIPF2,SLC17A6,PARP11,UBE3B,KAT6A,CASC15,CERS6,ADAMTSL3,ZNF248,SLC39A12,SLC4A10,FAM198A" MicroRNA hsa-miR-3138:mirSVR_lowEffct hsa-miR-3138:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.64E-151 2.04E-147 9.13E-150 8.41E-149 420 1898 "SYN3,ASIC2,ASIC1,NBAT1,ACTN1,NDRG3,TMEM132B,PSMG3-AS1,GALNT13,ADD2,ADD3,PLEKHH1,SNX30,NLGN4X,AP2A2,CASKIN1,AK2,ARHGAP20,GPRASP2,BEGAIN,AMPD2,ANK3,MYH7B,PPFIA1,DGKZ,DGKD,PPFIA3,USP37,CDC14B,MIER1,SEMA4G,MADD,IGDCC4,CASK,ARNTL,ARRB1,PLA2G4C,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,TMEM108,RIPK1,ADAM23,CARMIL3,ADGRB3,LINC00847,SEC11C,RGS11,DCAF5,FGF17,SCAPER,CASTOR3,BAIAP3,MMD2,CAMK2B,CAPN3,BRSK2,RUNX1T1,CBR1,CBS,SHISA7,CLDN10,USP6,CD86,ENTPD6,C1orf52,CDC27,CDH10,ZMYM4,LGI1,L3MBTL4,DLGAP2,CCPG1,SRSF11,ASIC3,PLEKHB1,NDST3,DGCR9,FADS2,DNAJB5,QKI,TMEM184B,SRP14-AS1,IGLON5,ARHGEF6,COL11A2,AKAP5,IFFO1,TBPL1,TOGARAM2,CLOCK,CDC42BPB,CREM,CREB5,GDA,SNCAIP,SEC24C,MICAL2,OSBPL3,ATRNL1,SOCS5,CNTNAP2,PLXNA4,FAM169A,KIAA0040,CTH,CTNND2,NRSN1,RIMS2,DCAF4,RUBCN,NOS1AP,ARHGAP32,DCAF8,PHYHIP,IST1,DAPK1,SCRN1,GIT2,SIRPA,ARMCX2,C8orf34,ZEB2,MYEF2,MAGI2,POM121,SMG7,SPOCK3,ZNF582-AS1,DLG2,DNM1,HS3ST2,SLC29A4,CDON,DPP6,DUSP9,AASDH,EDN1,EDNRB,SYT15,EFNB3,APH1A,KMT5B,ELAVL4,PCOLCE2,EPB41L1,LRRC17,MTSS1L,SEZ6,EPHA5,RABEPK,MRVI1,EZH1,F3,ZIC4,ATP8A1,CHST15,FCGRT,ZNF589,GORAB,SEC24B,FER,GTF2IRD2,POLR1B,SPSB4,FGFR1,EVL,FLT1,ANKFY1,SYT3,POMT1,STAMBP,ERGIC3,MSANTD4,TPPP3,AP4B1,GALNT15,BRPF3,SALL3,ZNF234,ZNF559,ATP8A2,ALDH1L1,SULT1C4,GGTA1P,GGT7,ZNF276,TTBK1,COPS8,SPIN1,STARD3,CBX1,GNAL,CNDP1,TDRKH,GPR22,GRB10,DIDO1,GRID1,ADAMTS13,GRM1,GRM7,CIT,GSTM5,RNFT2,GUCY1A1,SLC2A6,FAM222A,UBE2QL1,ARHGAP36,MIER3,LRRC75A,HSP90AA1,IDH3B,IL11RA,ZNF678,LRRTM1,SLC35G1,KCNH1,KCNJ3,TTYH2,NCOA7,MAN2A2,MAP2,MARK1,MAT2A,MATN3,SYT9,LDLRAD3,MEIS2,KITLG,SCAMP5,PPM1L,POC1B,AFF1,XRRA1,MMP16,N6AMT1,MDGA1,LYRM9,MYO6,HNRNPM,SFR1,NTRK3,NUCB2,OMG,OXTR,PC,DPY19L2P2,PCSK2,GNG2,TMOD2,PFKFB4,ZDHHC8,PKD1,XRN1,NLE1,FAM216A,PLCB2,PLEC,PCDH18,PURG,PNMA3,ING3,RETREG2,SEPT4,POLR2F,FSD1,PRKACB,RAB39A,PRKCZ,MAPK4,MAPK9,PRODH,SIDT1,GON4L,PTPRB,OCIAD1,PTPRD,PTPRE,CASTOR1,PEX5,NKAIN1,PID1,FAT4,RAP1GAP,NWD1,ZDHHC14,BSDC1,GAL3ST4,TRIM68,RFX5,UBR7,MRPS18A,ARMC5,ROBO2,ELP2,EPHA10,RPL15,UEVLD,STK32B,MAP6D1,LRRK2,MEG3,ABCA11P,DGLUCY,SEMA6D,LRRTM4,SCNN1D,SCP2,SLC30A10,COPZ1,RASA3,ITSN1,FERMT1,MAGI3,R3HDM2,ST6GAL1,CTXN2,DZIP1,PAAF1,LIMS2,PKNOX2,SLC6A8,SLC8A3,CCDC88A,CXXC4,MAST1,RCOR3,INAVA,MAPKBP1,KIF13A,RBM34,USP33,SOX1,SOX2,SOX3,BDP1,NMNAT2,ARHGAP26,KIF1B,ZBTB43,SPART,NFASC,SRPK2,TAB2,ITPRID2,LARP4,LRRC4,SSPO,MAPK8IP3,STX1A,SEPT3,VAMP1,ADAMTS17,PLCB1,C12orf76,PJA1,CAMSAP2,PDLIM2,UNC5D,ALG1,TBCEL,FBXW11,KLHL4,ACSL6,SIN3B,TCF7L2,USP22,SZT2,OBSL1,USP32P1,TNS2,HIF3A,DICER1-AS1,C18orf54,TGFBR3,SLC44A1,ACTR6,TLL2,ZFP91,HEY2,KAT6B,WBP2,RGMB,SYNPO2,PRMT8,TRPC1,TRPS1,CLHC1,UCHL1,ZNF709,VIPR2,TBC1D15,GUSBP1,ZIC1,ZNF708,SLC26A10,ZNF138,POLR3H,SPIRE1,ZNF213,SLC30A4,EMSY,MFF,SCG2,NAV3,FIP1L1,ITM2C,FAM47E,UBE3B,FBXO36,CASC15,ADAMTSL3,JMJD1C,TRAM2-AS1,ST8SIA2,SPATA13" MicroRNA hsa-miR-519d:mirSVR_highEffct hsa-miR-519d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.74E-151 2.66E-147 1.18E-149 1.09E-148 365 1440 "KCNH8,NCKAP5,SORCS1,SLC24A4,ABCD2,MRTFA,SEMA7A,USP28,SUGT1P4-STRA6LP-CCDC180,APP,SHTN1,AQP4,LINC00173,STK33,CAPRIN2,RASL11B,ASTN1,ATP1A2,SLC4A4,ATP1B3,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,NRP2,SCAPER,MTMR3,JAZF1,CALB2,MAP7,USP6,C1orf52,TIGD7,CLGN,CFL2,CHGA,JAM2,TAOK2,EPS15L1,ZFYVE9,ABCG2,SLC25A27,AKAP5,AHCTF1,ACBD5,CNRIP1,HS3ST5,CPS1,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,NRSN1,PPP6R2,CYBB,BOC,DOCK4,HDAC9,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,ZC3H11A,PLPPR4,SACS,OLIG1,USP3,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,SNX29,ANKRD46,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,DNAJC27,KATNAL1,GMPR2,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,ZMAT1,GABBR1,GABRA1,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,PPARGC1A,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,GRM7,CIT,LINC00839,TMEM25,AP4S1,IRAK3,HAS2,HPS5,HTR5A,MSL1,DOCK7,JAK1,METTL21A,OLFM3,KCNJ10,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,MEIS2,SRSF12,KITLG,MID1,POC1B,XRRA1,MOG,MSR1,MXI1,MYCN,MYH6,NACA,NCF2,SFR1,NELL1,NELL2,CNOT4,OCRL,OGG1,OPA1,GPR137C,CNTN3,PDE3B,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PRRX1,RETREG2,EPB41L4B,DRAM2,CRLS1,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,PTPRD,PTPRO,FAM120C,RAB5B,CEP97,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,SYBU,WDR37,BTBD3,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,SOX3,IQSEC2,ZBTB43,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SYNE1,PCDHB10,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,UCHL1,CCDC14,VLDLR,TBC1D15,ZBTB14,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,PCDH15,SLC17A7,FAM47E,WNK3,WNK2,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,DPF3" MicroRNA hsa-miR-3184:mirSVR_lowEffct hsa-miR-3184:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-151 2.91E-147 1.29E-149 1.19E-148 419 1891 "DPF1,ASIC2,ACHE,AS3MT,NBAT1,ACTN1,CSMD2,GPRIN1,PLEKHG5,ADCY6,ADD2,ADD3,OLMALINC,SNX32,KIAA1324,DISP3,AK2,PLA2G6,C1QTNF1,CARNS1,GOLGA7B,SYT13,PITPNM2,AMPH,KIF6,AMT,PI16,PHF12,APBB1,KCNAB2,PHYHD1,AMER3,TNRC6C,APP,MIER1,ARRB1,ARRB2,ASGR1,BRINP2,ALDH4A1,SLC4A4,ATP2B2,ATP2B3,CADM3,ADGRB2,SNAI3-AS1,RGS9,KSR1,SCAPER,GYG2,CDK5R2,DDR1,HAP1,TRIM41,CAPN3,BRSK2,PRC1,CBLN1,CBFA2T2,SYNGR3,CDC25B,ZMYM4,LRRFIP1,CRLF1,NUMBL,CACNA2D2,CHM,CHN2,SYNPR,B4GALT6,TAOK2,NDST3,KIAA1549L,TMEM59L,SRP14-AS1,ARHGEF6,CABP1,IFFO1,PNKD,C2CD2,MROH8,SEC24C,MICAL2,NCAN,SLITRK5,DZIP3,CMTM5,CTH,ARHGEF4,CTNND2,PUM1,RUBCN,NOS1AP,HDAC9,CENPL,EARS2,TM9SF4,SPOCK2,SIRPA,DBN1,MYEF2,B3GAT3,KIAA0319,KLHL3,TMEM130,POM121,PARD6A,SV2A,RABGAP1L,WDR20,DLG3,DNAH9,DNM2,FAM57B,DTNA,TOM1,ABCC5,SEZ6L2,ANKRD46,TMTC1,CACNG7,CELSR3,FAM13A,PHF20L1,EGR3,GOLGA7,ELN,OLIG2,DMTN,ANKRD13B,SLC43A2,STX2,ERBB2,DENND4A,SPEG,MRPL37,CEND1,REEP2,CORO2B,TOMM40L,FCGRT,SPSB4,FGFR1,BAIAP2,TMEM164,SCARA3,HPCAL4,IP6K2,AGAP2,IQCG,SGIP1,SYT3,DPYSL4,CINP,STAMBP,ARFGAP2,ADGRA1,TMEM151A,TBR1,GABBR1,GABRA3,JPH4,GHDC,IQGAP2,TMEM8B,DISC1,ALDH1L1,SRCAP,MSTN,AHDC1,GGT5,C1QL1,GJB1,ZNF276,TXNL4A,TCERG1,GPT2,GOLGB1,PRRC2B,LILRB4,PCLO,STMN2,GRIA1,GRIK3,ADAMTS13,GRIK5,GRM2,GRM3,TMEM25,RABL2A,SOX21,RNFT2,ATOH8,UBE2QL1,HBA1,PADI2,HRH3,ATXN2L,ARHGAP36,HPCA,OPALIN,ATCAY,MYLK2,LRRC25,ITGA7,C2CD4C,KCNA6,GPR62,KCNJ5,KCNK2,KCNN1,KCNN2,KCNQ3,KIF5C,A1BG-AS1,STMN1,MAG,MAOB,MARK1,ADAM11,LDLRAD3,SCAMP5,MOG,MOV10,GIT1,MSI1,BLOC1S2,BCO1,PTOV1,NRBP2,RSPO2,C10orf105,MYL3,MYO7A,NEXMIF,FXYD7,NBL1,NEFM,NEFH,OTOGL,NINJ2,DNHD1,NPTX2,PCBP3,NTRK3,NUCB1,P2RY1,PAK3,PALM,PCDH8,PCMT1,GDAP1L1,NOMO2,SNX10,PKM,KCTD15,EPN1,MTRF1L,SCHIP1,SEPT4,MBOAT7,POU6F1,MED1,NKAIN4,PRKCG,MAPK3,MAPK4,DIRAS2,MASP1,CNNM2,NDUFS7,WBP1L,GDPD2,PSMD13,PIGG,PTCH1,BDNF-AS,ELOVL2,CASTOR1,C1orf109,NKAIN1,RAB3A,RAD51D,IQSEC3,RAP1GDS1,RFX2,KCTD17,ARHGEF10L,SEC61A2,LGI2,TMLHE,ROBO1,EPHA10,SGSM1,STK32B,EMID1,SYNDIG1,ABCA11P,ATAT1,KCNIP3,WLS,YJEFN3,KCNIP2,CLIP1,RYR1,DGLUCY,SATB1,SBF1,ASIC4,IL17RB,CASC3,MRAS,FAM102A,FUZ,NTNG1,SHMT2,SLITRK3,ST3GAL3,CTXN2,DZIP1,RPH3A,PEX26,LIMS2,PKNOX2,LRRC55,SLC6A9,ARHGEF40,EFHD1,LGI3,NAXD,SMARCA4,SMARCC2,SORCS3,ANKRD36,MAPKBP1,UNC80,KDM4B,FAM219A,SON,WDTC1,MYT1L,TNIK,ZSWIM8,NMNAT2,CLUAP1,CDK19,TSPYL2,CAMTA2,MESP1,SSTR1,SSPO,SEPT8,SEPT3,NUDT10,SYN1,ARC,SYP,ROBO3,MLST8,EXOC7,TAL1,CNTN2,WWC1,TMEM136,MGRN1,ATMIN,AZIN2,TMEM151B,NSD1,ARHGAP9,AHCYL2,RNF216P1,TGFBR3,FBXL16,GALNT17,TK2,ICAM5,NR2E1,DAAM2,FAM124A,ANKRD24,RGMB,TRH,TRIO,TRO,STXBP4,TRPM2,NTSR2,SSBP2,GORASP1,PLEKHH2,PLPPR2,VGF,BEST1,LMF1,TSPAN11,KLC2,ATP6V0E2,PLPP4,NDRG4,CELF4,ZNF154,MEIS3,INTS3,EMSY,NT5M,RGMA,GDPD5,ADAMTS9,URM1,FIP1L1,WIPF2,DOCK8,CAMK1G,NUP214,JMJD1C,ADAMTS10,LAS1L,JPH3" MicroRNA hsa-miR-496:mirSVR_lowEffct hsa-miR-496:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.48E-151 3.08E-147 1.36E-149 1.25E-148 387 1619 "RALGAPA1,CLK4,ADD1,SORCS1,USP31,PWWP2A,SLC24A4,MTUS1,KLHL13,PCDH19,HACE1,OSBPL8,CC2D2A,LRRC7,ALCAM,ARHGAP20,FAM135A,ZNF687,CCDC146,MYH7B,CNIH2,MAGEE2,GPAM,ALS2,DDO,SHTN1,PPP4R4,ARHGAP5,ASCL1,PCDHGB4,CCDC181,ATP2B1,DPY19L3,RIPK1,ADGRB3,LINC00847,FUBP1,NAE1,BTK,PTBP2,CAST,MAP7,RUNX1T1,CDC42,MAGI1,NPIPA1,SRSF11,FOXN3,CNOT8,LHX2,KMT2C,KIAA1549L,COG1,C4orf33,HECTD1,NIPBL,PCYT1B,RCHY1,NRG2,IGDCC3,HS3ST5,RBM39,CREB5,NCOR2,TRIM69,FEZ1,IPCEF1,PLXNA4,FAM169A,KIAA0040,PLCXD3,RIMS2,DOCK4,HDAC4,ZFYVE16,CENPL,LONRF1,TBC1D5,MATR3,DAPK1,BRINP1,YTHDC1,DNAJC6,DGCR5,CEP170,SNAP91,MTX3,WDR20,SEC16A,USP3,DPYSL2,ABI1,DSCAM,RCAN1,ABCC9,E2F5,AASDH,EDNRB,PHC2,SEMA3D,PHF20L1,MBNL2,ABI2,GOLGA7,EIF4G2,PLEKHA1,PCOLCE2,USPL1,EPB41L2,KCNMB2,RABEPK,EPS8,DENND4A,IGSF6,CEP85L,ETV1,EZH1,ABCA8,FAM198B,ACSL4,ST3GAL6,CEP78,TOMM40L,FKTN,KIAA1109,FGF12,FGF14,POLK,MEX3B,FOXF2,ATP13A4,SGIP1,FAM49B,DACH2,GPR153,CSPG5,STAU2,MEGF10,GABRG1,GABRG2,HBS1L,ZMYND11,GALC,NCKAP1,ERAP1,MTHFD2,ATP8A2,MYOZ2,GCNT2,MSTN,WASHC2A,AHDC1,GFRA2,PPARGC1A,PCDH11X,ZNF638,MAP7D2,GNAL,FERMT2,GPM6B,LPAR4,GPER1,PCLO,GRIK2,GRM5,GRM7,RNF165,ADAMTS6,WIF1,UBE2QL1,MIER3,HNF4G,ZNF491,ZDHHC15,OPALIN,TCEAL6,SMAP1,FAAP20,IRF8,IGFBP1,NKD1,DOCK7,IL6ST,IBA57,BRINP3,ZNF678,KCND2,KCNH1,KCNK2,KCNN3,KCNQ2,KHK,KIF5C,KTN1,PAXBP1,HECTD2,ARHGAP12,MAP4,MARK1,MARK3,LDLRAD3,LRP1B,MEIS2,KITLG,WDR49,MOBP,ZNF680,SAMD5,SESN3,CCDC80,MTR,MYO7A,MYO9A,NEK1,NF1,ALDH1L2,CNOT4,NUCB2,CLDN11,PCDHGC3,PCSK2,PDE4D,PIRT,ENPP2,PFKFB3,ABCB1,PCDH18,SLC36A4,PPM1B,PPP2R2B,CRLS1,PPP3CA,RANBP3L,PRKAB2,MAPK9,MASP1,RELN,SNRK,CNTLN,ANKHD1,NCR3LG1,BDNF-AS,PTHLH,PTN,PTPRZ1,PTX3,TTC13,PID1,ZCWPW1,RADX,VEPH1,KHDRBS2,REV3L,UBR7,RGS4,SLC25A36,LGI2,ZNF532,TMEM100,RPL15,ZC3H14,RPL38,WLS,ZNF568,CCDC112,TRAPPC13,DGLUCY,SALL1,SCN2A,SMPD3,SEC14L1,SELL,COPZ1,RASA3,KIF16B,DOCK10,NTNG1,NLGN1,RPH3A,PPP4R3A,DHX30,ARHGEF40,CCDC88A,SCMH1,SLCO1A2,MYH15,INAVA,SNCA,KIF13A,FAM126B,UNC80,RBM34,USP33,TNIK,FNBP1,KDM3A,ZHX3,ENKUR,CAND2,HECW1,MYCBP2,SPP1,TEX2,RBM26,NPAS3,LMO3,C11orf87,TAB2,POGZ,ZC4H2,NKAIN2,STAU1,CEP68,ADHFE1,FGD4,ZC3H4,FNDC9,DDHD2,TAF9,EHBP1,SATB2,ZEB1,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RALYL,ZFPM2,ITGB3BP,LEFTY2,HHIP,ARL10,TIAM1,TMPO,DAAM2,FAM124A,CSMD1,ZNF384,SYNPO2,METTL3,AMACR,TRO,TRPC3,TRPS1,TTC3,SGK3,UBE2H,UGT8,DNAJC12,SLAIN1,PLEKHH2,NSD2,CLDND1,XRCC4,ZNF708,ZNF19,MICU3,ZNF74,ZNF138,ZSCAN26,PLPPR5,CA10,CSDE1,KCNAB1,WNK3,EPM2A,RGS7BP,DNAH10,DOCK8,ST7,FBXO36,ADAMTSL3,TIGD6,ZDHHC20,IFT88,RNF146,CPNE4" MicroRNA hsa-miR-155:mirSVR_highEffct hsa-miR-155:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.13E-151 3.44E-147 1.51E-149 1.39E-148 366 1449 "SDE2,ABAT,CLK4,ACTN2,CSMD3,FMNL2,ADD3,AXIN2,ERMN,PWWP2A,MTUS1,HECW2,TBC1D14,LRRC7,SPOP,ALCAM,ABCD2,ARHGAP20,FAM135A,ANK3,LCORL,MAP4K3,PPFIA1,APAF1,TNRC6C,USP37,SHTN1,MIER1,IGDCC4,ASPH,NUMB,DDX3Y,ATP2B3,SLC2A11,B3GALT2,BACH1,KSR1,DST,SCAPER,CASTOR3,KALRN,PTBP2,CAST,MAP7,INA,CD38,CCPG1,UBE2L6,RCBTB2,SOCS6,CHN2,CASC2,B4GALT6,CLCN3,NRXN1,NMT2,QKI,NIPBL,CNTN1,SLC4A8,MFSD4A,ENTPD4,ANKRD44,CLIP3,CSF1R,MICAL2,SIPA1L1,SOCS5,PLXNA4,PHF14,CTNND1,PUM1,ST18,DCAF4,BOC,TOX,TBC1D5,DAPK1,C8orf34,MYEF2,GSDME,G3BP2,KBTBD11,DLG2,GRIN3A,RAB39B,DYNC1I1,NR1D2,DMTF1,DRD1,DTNA,ABCC9,GOLT1B,E2F5,AASDH,EDNRB,KLHL5,FAM13A,PHF20L1,EGFR,MBNL2,LPAR6,KCTD3,ELAVL2,PLEKHA1,C3orf18,EML1,EN2,IGSF6,CEP85L,EYA1,FAM198B,EFEMP1,KIAA1109,FGF14,FHL1,ANKFY1,SGIP1,SMC2,UFM1,PDLIM5,NSG2,SARAF,NRG3,MEGF10,GABRA1,CAB39,ZMYND11,GALC,ARPP21,C15orf41,DISC1,KIAA1841,MYOZ2,GATM,SESN1,COPS8,DBF4,MSL3,ZNF638,DCLK2,GNAS,GPM6A,GPM6B,GRM8,KAT7,PSIP1,GUCY1B1,GYG1,MIER3,HPSE2,NEGR1,SHISA6,IRF8,SCIN,LIX1,DIPK1A,OLFM3,KCNMA1,KHK,KLRC3,STXBP5,L1CAM,LAMP2,LIG4,PAXBP1,HECTD2,NCOA7,C2orf80,SMAD1,MARK1,MBNL1,TM6SF1,LRP1B,MEIS1,MITF,AFDN,MMP16,ZNF680,ZNF92,CTNNA3,NAP1L2,NCAM1,ZC3H12B,NEFH,NEK1,NOVA1,SLC11A2,IGSF11,GLIPR1L2,CNTN3,PCDH9,PRTG,PDE3A,PDE4D,GPR85,PIK3C2A,FAM216A,STRN3,RC3H2,PRRX1,EPB41L4B,DRAM2,MINDY2,CRLS1,PRKACB,CEP41,PKIA,PKN2,SLC26A11,DIRAS2,LRRC49,WDR25,CNTLN,ELOVL2,PTN,TMEM260,PTPRB,PTPRD,PTPRG,PTPRN2,USP47,PLEKHB2,RAD51D,ARID4A,RBBP6,BSDC1,SLC6A15,ZYG11B,ZMAT4,REV3L,RNF220,PBRM1,CCDC82,DCUN1D2,CARF,CYB561D1,ROBO2,RPE,NEK11,ABCA11P,TRAPPC13,FAM192A,S100B,SATB1,SCN2A,SCN3A,LRRTM4,SCN7A,ELMOD1,IL17RB,KIF21A,ITSN1,SH3GL2,MAGI3,CHD9,FBXO11,NLGN1,PAAF1,SLA,BTBD3,RUFY2,SEPHS1,SLC12A2,SLC15A2,BTBD7,SLC20A2,SMARCA4,ANKRD36,LIMCH1,SNAP25,SNRPN,PALLD,FAM126B,UNC80,SOX1,KIF21B,SOX11,CLUAP1,HECW1,KDM4C,ZC3H13,RBM26,SPART,TAB2,STOX1,NKAIN2,CEP68,RGL1,SYNE2,VPS13A,NUDT10,PLCB1,SYPL1,C12orf76,TACC1,CAMTA1,FAM208A,ADGRL3,WWC1,TBCEL,KLHL4,TCF7L2,TCF12,SYNE1,DOCK9,PCDHB10,PCDHB9,SLC19A3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,AKTIP,ASXL3,DDHD1,FAM124A,CSMD1,C5orf64,TPM1,RGMB,TRPS1,RFTN2,ZKSCAN5,CLHC1,SGK3,UBE2H,PLEKHH2,CCDC14,TBC1D15,LAT2,ZNF781,RICTOR,SLC13A3,ZIC3,ZNF28,TRIM9,CELF4,ZBTB38,FSTL5,PRTFDC1,CSDE1,RNF103,SCG2,VPS35L,NAV3,FAM47E,PDSS2,EPM2A,RGS7BP,AMN1,PAK5,KAT6A,HNRNPA3,CASC15,ADAMTSL3,SSPN,FXR1,FRMD6,NETO1,SLC4A10" MicroRNA hsa-miR-106b:mirSVR_highEffct hsa-miR-106b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-150 8.34E-147 3.64E-149 3.35E-148 375 1525 "KCNH8,NCKAP5,SORCS1,SLC24A4,HACE1,C1QTNF3,ABCD2,MRTFA,SEMA7A,USP28,SUGT1P4-STRA6LP-CCDC180,TNRC6C,APP,SHTN1,AQP4,LINC00173,STK33,CAPRIN2,RASL11B,ASTN1,ATP1A2,SLC4A4,ATP1B3,ATP2B1,B3GALT2,NOL4,DPY19L3,ADGRB3,NRP2,ARHGEF7,MTMR3,JAZF1,CALB2,THSD7A,MAP7,USP6,C1orf52,CDH10,LGI1,TIGD7,CFL2,TAOK2,EPS15L1,IGFBP7-AS1,ZFYVE9,ABCG2,SULT4A1,ARMC8,COL4A5,SLC25A27,AKAP5,AHCTF1,ACBD5,CNRIP1,HS3ST5,CLOCK,CREM,ENTPD4,CRY2,ANKRD44,LRIG1,FEZ2,ARHGEF10,CHD5,PDE4DIP,UBXN2A,CTNND1,NRSN1,PPP6R2,CYBB,BOC,DOCK4,GAPVD1,ARHGAP24,ZFYVE16,RASSF2,TOMM20,SIRPA,DNAL1,C8orf34,ZEB2,MYEF2,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,OLIG1,USP3,DMTF1,DPYSL2,DRD1,FAM78B,DNAJB6,DYRK1A,DNM1L,ABCC9,E2F5,ANKRD46,EFNA3,FAM13A,SUGP2,KMT5B,EIF4G2,IRAK4,COPS4,TENM1,ELAVL2,PLEKHA1,CERCAM,MRNIP,EPHA5,KCNMB2,DNAJC27,KATNAL1,EZH1,F3,WAC,ACSL4,TAOK3,CORO2B,CEP78,FER,MED12L,SUCO,SEMA4D,FLT1,NBEA,TACC2,SPECC1,USP16,UFM1,PDLIM5,ST6GALNAC3,GABBR1,GABRA1,TRAF3IP2,HBS1L,B4GALNT1,ARPP21,NCKAP1,ERAP1,SYT17,DISC1,WASF3,MYOZ2,RAB30,TNRC6A,DCLK2,TDRKH,GPR37,RAPGEF4,GRM7,CIT,LINC00839,TMEM25,AP4S1,IRAK3,HAS2,HPS5,HTR5A,MSL1,DOCK7,RIPPLY2,JAK1,METTL21A,OLFM3,KCNJ10,KCNMA1,KCNN2,KIF5A,KIF5C,KLC1,SFXN5,SYTL4,HECTD2,ARHGAP12,SMAD1,MAN2A2,MAP6,AQP11,MDM4,LRP1B,SRSF12,MID1,POC1B,XRRA1,MOG,CD200,MSR1,MXI1,MYCN,MYH6,NCF2,SFR1,NELL2,CNOT4,NTRK3,OCRL,OGG1,GPR137C,CNTN3,ETFRF1,PDE3B,PDE4D,PDE1B,PDGFRA,BEST3,PFKP,ZDHHC8,CCSER2,JAKMIP1,PRRX1,SPATA6,RETREG2,EPB41L4B,DRAM2,PPP2R5E,PPP3CA,PPP3CB,PRKACB,PKIA,PKN2,HYDIN,PSD,VPS13C,SLC22A23,PIGG,PTHLH,PTPN13,PTPRD,PTPRO,RAB5B,CEP97,USP47,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,ZYG11B,REV3L,GTDC1,SLC25A36,RNASEL,RNH1,CCDC82,ZNF532,RAVER2,CARF,TMEM100,UEVLD,ZNF671,MCMBP,CNTNAP3,ST6GALNAC6,FAM182A,AMER2,SALL1,CSRNP3,LRFN5,SCN2A,SCN3A,FAM19A1,SH3GL3,MAGI3,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,RUFY2,LRRC55,ARHGEF40,CCDC88A,SLC11A1,TET1,GKAP1,SMARCD3,IFT122,RIMS1,MBD5,CMTR2,SNRPN,UNC80,RBM34,USP33,MYT1L,IQSEC2,ZBTB43,NPAS3,SPART,LMO3,SRPK2,ATP10B,ITPRID2,SMOC1,ERBIN,RGL1,ADHFE1,FGD4,SYNE2,PLCB1,ANKRD12,CAMTA1,AGTPBP1,TBCEL,FBXW11,ATMIN,SATB2,SYNE1,RALYL,FAM189A1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,AKTIP,THRA,TIAM1,ZFP91,RIMBP2,TNS1,NPL,RGMB,UBC,UBE3A,UBTF,PLEKHH2,CCDC14,VLDLR,TBC1D15,PCDH20,ZBTB14,ZNF23,MICU3,ZNF74,LYPD6,TCEAL7,ZSCAN26,ANKS1B,LAMP5,CA10,MAP3K12,EMSY,CADM2,SLC38A1,RGMA,CSDE1,PRDM10,PCDH15,SLC17A7,FAM47E,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,UBE3B,PAK5,PHTF2,FAM219B,NLRP3,FXR1,FRMD6,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-188-3p:mirSVR_lowEffct hsa-miR-188-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-150 9.84E-147 4.28E-149 3.94E-148 419 1897 "DPF1,CLK4,ACTN1,NDRG2,BRAP,SLC12A5,RNF150,SLC24A4,SNX32,NR0B1,C1QTNF3,ARHGAP20,PCDH10,MYH7B,PPFIA4,CNIH2,CNTNAP1,APBB2,DGKZ,GPAM,CPNE5,LGR5,SHROOM2,SEMA4G,CASK,SPTBN4,ARRB1,ARRB2,CAPRIN2,ASPH,CHRD,CCAR2,ALDH4A1,ALDH7A1,ADAM15,AZGP1,BBS2,NRP2,PROM1,CDK5R1,ARHGEF7,FUBP1,BTK,NIPA1,CDK5R2,CA8,DDR1,CACNB2,CACNB4,KALRN,TRIM41,CANX,ISPD,RUNX1T1,CBLN1,ZNF501,CLDN10,LDB2,INA,REPS2,CDC27,ZMYM4,CCPG1,CHI3L2,NDST3,RAB33A,NRXN3,CLCN4,NMT2,DGCR9,CLTC,TJP2,SRP14-AS1,HECTD1,LY86,AKAP7,IQCK,LETMD1,SLC4A7,IFFO1,SMARCAL1,MFSD4A,SEC31B,CREM,RGS6,CSF2RA,MICAL2,ATRNL1,IPCEF1,SLITRK5,KIAA0040,ERC2,DCAF4,CYBB,DOCK4,ARHGAP32,GAPVD1,SNPH,FRMPD4,RASSF2,MAML1,IST1,B3GAT3,CNIH3,C2CD2L,GSDME,PLPPR4,SNAP91,SRGAP3,WDR20,DLX1,GRIN3A,DMD,HS3ST4,DMPK,DOCK2,DPH1,ABI1,DRP2,DTNA,ABCC5,DNM1L,AASDH,EBF1,WDPCP,EDN1,EDN3,PHC2,HIPK3,GPR61,APH1A,EGFR,MBNL2,KMT5B,EIF4G2,EIF5,C8orf37,DCTN4,ENO2,VPS13B,EPB41,SEZ6,KCNMB2,RABEPK,ZNF549,RCSD1,SIRPB1,WAC,TUBB4A,SCML2,FCGR1A,FCGR3A,TOMM40L,FCGRT,SPSB4,FGFR1,BAIAP2,FOXG1,FOXF2,IP6K2,VTI1B,AGAP3,RGPD5,FOXM1,SEMA4D,WDR83,SPECC1,NPTN,CELF1,NSG1,STAU2,GABBR1,HRASLS5,GALNT15,HBS1L,RAPGEF6,GAP43,C15orf41,ATP8A2,GART,TUBGCP4,SESN1,HEPN1,GHR,TXNL4A,HPGDS,GLYR1,CBX1,KDM2B,GNAS,GPD1,STON1,GPER1,CECR2,ADAMTS13,SERP2,GRIN2C,KIF3A,RNF165,PTPN5,TMEM25,LINC01551,RABL2A,MUM1,MAEL,RASSF8,HPS5,TOX2,PADI2,ARHGAP19,SMAP1,IGF1,IGFBP1,IL11RA,ZNF678,RIPPLY2,INPP5B,KCNJ9,KCNJ11,KIF5C,LINC00634,INSYN2,SYTL4,ASPRV1,SMAD9,MAN2A2,MAOB,MAP2,MARK1,MBD1,MBP,MDM4,MEIS1,PPM1L,MOBP,MT3,HS6ST3,NDP,NF1,DNHD1,SMIM11A,SETD4,OPA1,OPHN1,KCNK10,SNTG1,PAK3,PBX1,PCSK5,PDE2A,PDE3B,PDE4A,PIRT,PFKFB2,ZDHHC8,NLGN3,ZFYVE21,GPSM2,PLCB2,ST8SIA5,TRHDE,EXOSC10,RETREG2,PPARA,TMEM235,PPP1R1A,CRLS1,PTPA,PPP2R5E,KANSL1,PRKAB2,MAPK4,PSD,CNTLN,PTCH1,NKAIN1,TUG1,PID1,FAM66C,SH3TC2,RAP1GAP,RDX,RFX2,RFX3,RFX5,ARHGEF10L,TTLL7,MRPS18A,RIC8B,TMLHE,C12orf49,ALG9,ROBO2,SNX22,FBXW7,SPIN3,CLIP1,RYR3,FAM182A,DGLUCY,ATXN1,ATXN2,ATXN7,SCN2B,SCN7A,LINC00461,PRCD,TNFRSF19,ASIC4,SOX6,CASC3,GALNT10,COPZ1,SGK1,KIF21A,PPM1E,MYO18A,CNKSR2,NLGN1,CTXN2,ANKRD6,NUBPL,PAAF1,ABLIM3,SLC1A7,KANSL3,YPEL4,RADIL,SLC8A3,SLC12A2,SLC12A4,SLC15A2,TMEM132D,SCMH1,BTBD7,TET1,ZNF667,MBD5,SNRPN,ZCCHC24,TSNAXIP1,ZSWIM8,GLT8D1,EMC1,TSPYL2,RBM26,SPART,POGZ,RGL1,GANAB,SYT11,FGD4,JMJD6,ZC3H4,VAMP1,ANKRD28,ASTN2,ANKRD12,MTCL1,MLST8,EXOC7,UNC5D,TRIM2,TCF12,AZIN2,NAT16,DOCK9,AKNA,HIF3A,CYB561A3,ZNF106,THBS4,CDH22,THRA,TK2,TLL2,C5orf64,PIK3R5,TPM4,SYNPO2,DCBLD1,KCNE5,TMPRSS5,RPRM,UBE2H,UCHL1,FLRT2,ZNF709,PLPPR2,VLDLR,NSD2,CLDND1,XPO1,ZIC2,ZNF24,SLC26A10,ZNF154,EML6,SPIRE1,PMEPA1,GDPD5,LMAN2L,ADAMTS9,HPS4,PCDH15,KCNAB1,FAM47E,PCBP4,WIPF2,C12orf4,EPM2A,MARCH8,HNRNPA3,TMEM63C,FBXO36,MSRB3,TTC7A,SOCS4,LAS1L" MicroRNA hsa-miR-219-2-3p:mirSVR_lowEffct hsa-miR-219-2-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.99E-150 1.68E-146 7.27E-149 6.69E-148 411 1830 "CPNE2,ARID1A,CSMD3,FMNL2,CCDC85A,TMCC3,CDC7,KIAA1211,PTCHD1,SLC44A5,AP2A2,ZNF608,HECW2,OSBPL1A,OSBPL8,SPARCL1,SEMA6A,ALCAM,UNC79,FAM135A,ZNF687,DPP10,ANK3,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,TNRC6C,LGR5,AQP4,CDC14B,SEMA4G,ARHGAP5,CAPRIN2,ATM,SLC4A4,EIF4G3,ATP2B3,N4BP2L1,NOL4,BACH1,ADGRB3,LINC00847,BBS2,MPDZ,SEC11C,BCL7A,DCAF5,PROM1,KSR1,GYG2,SGCE,WASF1,CACNA1A,VXN,VSTM2A,CARS,ISPD,PRC1,MTMR7,SLC16A4,P2RX6,TMEM257,CDC27,ZBED1,CDC42,CDH2,DCLK1,LRRFIP1,LGI1,CLGN,CHGB,CHM,CASC2,SYNPR,RAB3C,NRXN1,TPP1,ABCG2,CNTN1,ARMC8,CP,SEC31B,CDC42BPB,C2CD2,LRIG1,MICAL2,OSBPL3,ATRNL1,PLXNA4,KIAA0040,CTNND2,RUBCN,USP6NL,ARHGAP32,FGFR1OP2,TBC1D5,DAPK1,SPOCK2,SPATA2,YTHDC1,DNAJC6,ZBTB24,BLOC1S6,DDX46,SGSM2,WDR20,DLG2,RAB39B,DMD,USP3,DMTF1,DNAJB6,DYRK1A,DNM1L,GOLT1B,ATL1,FCF1,FSD1L,MRO,MBNL2,AASS,EIF5,TENM1,PLEKHA1,ELAVL4,EML1,STARD3NL,USPL1,EPHA5,EPHB1,RABEPK,STX2,EPS8,EYA1,FAM198B,CEP78,PPP1R1B,GORAB,POLK,SUCO,PCYOX1,SGIP1,AFF2,AKAP3,NBEA,SORBS1,APOPT1,STAMBP,ATP2C1,ST6GALNAC3,TBR1,AP4B1,NRG3,TVP23A,OGA,STAG2,GAB1,GABRA2,GALNT15,GAD2,ZMYND11,NEK6,GHDC,IQGAP2,C15orf41,DISC1,ATP8A2,LRRC37A6P,MYOZ2,TUBGCP4,ARFIP1,GDF9,CYP46A1,ADAM28,FREM1,NTNG2,TCERG1,KDM2B,LUZP2,GNAS,CNDP1,GPD2,GPM6B,LILRA1,GPR37,TMEM121B,GRIA2,ADAMTS13,GRIN2C,GRM1,PRDM5,GRM5,GRM7,SOX21,ADAMTS6,MAP4K5,MIER3,ELOVL5,HMGB1,HMGCR,LRRC75A,SHISA6,IRF8,IGF1,LRRCC1,USP54,SLC6A17,INSM1,ZNF385B,SLC35G1,KCNA6,KCND2,KCNJ10,KCNJ16,KCNK2,KPNA5,INSYN2,SFXN5,PAXBP1,LMO2,PACRG,MAT2A,AQP11,MBNL1,MEF2C,KITLG,MMP16,MOBP,CD200,SAMD5,SESN3,ADAM22,N6AMT1,MYO5A,MYO6,ZC3H12B,NELL1,NEUROD1,NFE2L2,ALDH1L2,DNHD1,SLC11A2,OXTR,P2RX7,CNTN3,PCDH9,PCSK5,PDCD2,GPR85,GNG2,CAMKV,PIK3R1,RETREG1,FAM216A,PDZRN4,PMP22,ING3,POU3F2,PPP2R2B,CRLS1,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,SAMD9,VPS13C,SIDT1,QRICH1,CNTLN,PTN,STK32A,OCIAD1,EML5,PTPRN2,ZNF615,ZNF844,PID1,SH3TC2,OXR1,RBBP8,HKR1,MSANTD2,FIGN,RFX2,TTLL7,EXD2,ROBO2,RORB,CCDC102B,RPE65,RPL15,GLDN,RTN1,RYR3,CCDC112,RMI1,AMER2,FOXRED2,MIR124-2HG,SATB1,LRFN5,TRIM46,MRAS,SUPT20H,HSPA4L,KIF21A,MAGI3,CHD9,ST6GAL1,ST3GAL3,SLC1A7,PPP4R3A,SLC8A1,BTBD7,IFT122,LIMCH1,RIMS1,SNCB,MBD5,KIF13A,CABCOCO1,SCN3B,DOP1A,SOX5,SOX10,DOK5,ZNF423,KIF1B,CDK19,TSPYL2,RBM26,NFASC,SRPK2,ZSCAN29,NEK4,SEPT8,SEPT3,ACSBG1,FGD4,ARHGEF9,VPS13A,PLCB1,TAC1,CAMTA1,DNMBP,ADGRL3,TBCEL,KLHL4,MGRN1,VWA3A,WSCD1,ACSL6,CUX2,TCF7,DOCK9,RALYL,AKNA,GPRIN3,ZFPM2,CRB1,AKTIP,TJP1,TK2,TLL2,LRRC8A,R3HDM1,TNR,SEZ6L,TPM1,TSN,TTTY15,SGK3,SLAIN1,MICAL1,VSNL1,WIPF1,P2RY12,WNT7A,WRN,PORCN,GUSBP1,XPO1,XRCC4,SLC47A2,PCDH20,ZNF24,ZNF28,TRIM9,AGMO,LYPD6,ZNF142,ANKS1B,CA10,MFF,PRDM2,PRTFDC1,TRIM16L,WNK3,WNK2,SLC17A6,FAM13C,FZD3,JMJD1C,ZNF248,RNF170,SLC39A12,KLHDC1,NETO1,CBLN2,ST8SIA2,SENP7" MicroRNA hsa-miR-299-3p:mirSVR_lowEffct hsa-miR-299-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.14E-150 2.32E-146 1.00E-148 9.23E-148 379 1562 "RALGAPA1,ASIC1,SYS1,FMNL2,GALNT16,SLITRK1,ADCY6,GRAMD1B,ADORA1,RNF150,LRFN2,DPY19L2P4,SNX32,KIAA1324,WDR35,OSBPL8,SEMA6A,ALCAM,PCDH10,AMPD2,LRFN1,ANK1,SEMA7A,CCDC146,MAP4K3,PPFIA2,PKP4,ANXA7,FAM131A,CDC14B,SLC7A14,KIAA1614,SEMA4G,IGDCC4,TMEFF1,ARNTL,ARRB1,MARCH3,NUMB,ATP1A2,SLC2A11,B3GALT2,BID,KSR1,BTK,GPC2,WASF1,CA8,HAP1,TRIM41,CAST,ISPD,KYAT1,KRIT1,MTMR7,CDC25B,CDC42,CDH8,ARHGAP33,EVI5L,MAGI1,COPB2,CHRM1,PLEKHB1,CASC2,SYNPR,LHX2,COG1,QKI,SULT4A1,IGLON5,CNTFR,MAGED1,IGDCC3,CLOCK,CREM,CLIP3,CSF2RA,CST3,FAM169A,ARHGEF4,NRSN1,ST18,FAM131B,ECE2,CCDC144A,DOCK4,HDAC9,MYADM,ZFYVE16,EARS2,INTS1,SCRN1,GIT2,ELMSAN1,DNAJC6,ZEB2,HEPH,ELMO1,TIAM2,DDX46,SPOCK3,SRGAP3,ARNT2,DLG2,DLG3,HS3ST4,CD99L2,DYNC1I1,DMTF1,ABI1,PDCD6IP,ARRDC4,ECM2,DNAJB6,DNM1L,ABCC9,EDN3,EDNRA,EDNRB,CNNM1,YAF2,EFNB3,APH1A,EGFR,EGR3,GOLGA7,IRAK4,ELAVL4,RGS17,USPL1,EPB41,MTSS1L,GPHN,EPS8,IGSF6,CEP85L,ZNF549,EYA1,EZH1,REEP2,CORO2B,CEP78,FCGR3A,KAT8,PPP1R1B,SLC9B2,FER,OLFM1,FGF11,BAIAP2,AMOTL2,HPCAL4,IP6K2,JKAMP,SMC2,ATP2C1,ZNF605,ERGIC3,CSPG5,STAU2,MEGF11,MEGF10,GABRA2,CHL1,RAPGEF6,C15orf41,KIAA1841,MSTN,USP19,GLS,TOX3,TNRC6A,MSL3,ZNF638,MAP7D2,GNAS,GRIA2,GRIN1,TMEM25,RABL2A,FAM107A,GUCY1B1,CELF3,PADI2,SCRG1,ZDHHC15,CPT1C,DHX35,IGF1,LRRCC1,SCIN,INSM1,ITGAV,OLFM3,KCNA6,KCNC2,KCNJ9,KCNJ10,KCNJ16,CREG2,KLRC2,L1CAM,LAMP2,LIFR,VWA5A,MARK1,MBD1,SYT9,MDM4,MEST,MID1,MOBP,CD200,GIT1,MSI1,JAKMIP3,RSPO2,PABPC1L2A,P2RY13,NCAM1,SFR1,NME4,SLC11A2,NTRK2,NUCB2,NUMA1,OPCML,LOC100128398,OXTR,P2RY1,CNTN3,CDK18,PDE1A,PDE4D,ENPP2,XRN1,KCTD15,PLCB2,PLIN1,C11orf49,PDZRN4,STRN3,PRRX1,POU3F2,PPARA,MED1,NKAIN4,CEP41,RAB39A,HYDIN,MASP1,RELN,LAMA1,TMEM104,CNTLN,BDNF-AS,PTPRN,PTPRO,RAD52,SH3TC2,ATG16L1,RASGRF2,ZDHHC14,GTDC1,UBR7,SEC61A2,RIC8B,KLHDC8A,ALG9,ROBO2,NEK11,ZNF671,MCMBP,SGSM1,ADAL,ZNF331,CSRNP3,SCN4B,SCG5,ASAP3,NTNG1,ST3GAL3,SLC8A2,RAB3GAP1,SLC8A3,ELMO2,ATF7IP,MAST1,SORCS3,SNRPN,PDZD2,WDTC1,SOX1,SOX10,KDM4C,PEG10,ZBTB43,TSPYL2,ATP10B,CLSTN2,CAMTA2,POGZ,STOX1,SMOC1,DIP2A,STX1A,KANK1,GSE1,ACSBG1,FGD4,ZFR2,VAMP1,ARHGEF9,FNDC9,C3orf70,MTCL1,MLST8,UNC5D,VWA3A,SIN3B,SATB2,TRIM2,RPGRIP1L,NAT16,DOCK9,NSD1,PUM2,TNS2,CYB561A3,ATP13A2,PMS2CL,CRB1,LEFTY2,TMEM9,FAM124A,R3HDM1,TPM1,SYNPO2,PRMT8,TRPC1,TRPS1,SSBP2,RFTN2,UBE3A,PLEKHH2,ZNF709,VLDLR,WIPF1,RICTOR,LGI4,ZIC1,ZIC2,TRIM9,FMN2,LYPD6,DPYSL5,PLPPR5,DHX33,WNK1,SLC30A4,PRDM2,NT5M,DNALI1,GDPD5,LINC02210,XKR7,PCDH15,GAL3ST3,NAV2,PARP11,RGS7BP,ST7,NUP214,ACTR3B,PIANP,NETO1,GAN,SPATA13" MicroRNA hsa-miR-382:mirSVR_lowEffct hsa-miR-382:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.88E-150 2.74E-146 1.18E-148 1.08E-147 400 1738 "ABR,EMILIN3,NCKAP5,NBAT1,XKR4,CSMD3,NDRG2,CCDC85A,ESYT2,PTCHD1,FAHD2CP,DPY19L2P4,SLC44A5,GPR158,KLHL13,CASKIN1,OSBPL1A,WDR35,ADGRF5,ABCD2,PCDH10,BBOX1,SYT13,CDC42BPA,LRCH2,CCDC146,PPFIA1,APC,EPB41L5,MAGEE2,LGR5,AQP4,ARHGAP5,CADPS,CDK13,ASCL1,NUMB,ATM,ATP1B3,ATP2B3,DOCK11,ADAM15,RGS9,BCL7A,DCAF5,SCAPER,OSGIN2,CA12,CALB1,CALB2,CABP7,CALM1,KALRN,PTBP2,MTMR7,P2RX6,DGKI,AP4M1,CDC27,CDH8,LGI1,CHGA,CASC2,B4GALT6,LHX2,NRXN3,IGFBP7-AS1,NRXN1,TPP1,FBXO7,CNR1,CNTN1,ARMC8,BTF3L4,AKAP5,ABI3BP,RCHY1,RTTN,TOGARAM2,MYRIP,ZNF521,ZFP28,C2CD2,CRMP1,HAPLN1,ANKRD44,GDA,SEC24C,ATRNL1,CST3,FAM169A,SLITRK5,DZIP3,UBXN2A,RIMS2,USP6NL,DOCK4,PHF19,KIAA0513,MATR3,KIAA0586,DGKB,DGKG,TOMM20,BRINP1,AIF1L,SIRPA,DCC,DNAJC6,DGCR5,MYEF2,KIAA0753,CEP170,NTM,DLG2,DRD1,ABI1,DTNA,DNAJB6,DYRK1A,EDN1,SYT15,SEMA3D,KLHL5,TMTC1,RBM12,FAM13A,PAN3,USPL1,TUBD1,GPHN,ERBB4,ETV1,DNAJC27,EZH1,F5,FAM198B,ATP8A1,CEP78,TOMM40L,FGF13,EVL,HVCN1,PDLIM5,DACH2,GPR153,MEGF11,MEGF10,GABRA2,HBS1L,BRPF3,ARPP21,NCKAP1,TMEM8B,SRRM4,SRCAP,ARFIP1,ADAM28,HEPN1,GHR,DHRS4,BRD8,COPS8,GLUL,OS9,LNX1,GOLGB1,GPM6A,TDRKH,GPR37,TPPP,C1QL4,NR3C1,GRM7,KIF3A,KAT7,MFSD2A,PSIP1,ADAMTS6,MAEL,RASSF8,FRMD3,ARHGAP19,HNMT,C9orf129,AGFG1,SMAP1,FAM95B1,C2orf72,GAREM2,NIM1K,KNDC1,IL6ST,IL12A,INPP5B,SLC35G1,GPR62,KCNN3,STMN1,PAXBP1,HECTD2,C2orf80,GPR155,MBD1,CHIC1,MDM4,MEF2C,PPM1L,MITF,AFDN,MOBP,ADAM22,TAGLN3,NACA,NCAM1,CCDC13,NF1,NFE2L2,OPA1,KCNK10,SNTG1,PAX6,PBX1,PCDH8,PCSK2,PRTG,PDE1C,PDE4D,OLA1,GDAP1L1,SSH1,ZNF655,KCTD15,GPSM2,MTRF1L,PURG,PMP22,FAT3,PPM1B,CEP41,PRKCZ,MAPK4,PROX1,BCAS3,SIDT1,MDGA2,QRICH1,PIGG,PTHLH,EML5,PTPRG,PTPRZ1,TTC13,TUG1,TMEM255A,ZNF793,SH3TC2,FAM184A,RASGRF1,ARID4A,DBX2,KHDRBS2,MSANTD2,SLC25A36,RPRD1A,LGI2,ZNF532,EXD2,RORB,RPE,NEK11,ARMH4,FBXW7,GLDN,HSD11B1L,ATAT1,RTN1,ZNF354C,DGLUCY,AMER2,SEMA6D,TNFRSF19,ZFP2,SOX6,MRAS,TRA2B,SCAF8,ITSN1,SH3GL3,FERMT1,CPEB3,FBXO11,NLGN1,DZIP1,ZNF365,PPP4R3A,RUFY2,SLC8A2,YPEL4,SEPHS1,RAB3GAP1,SIRT2,CCDC88A,BTBD7,SLCO1A2,SLN,ANKRD36,RIMS1,KIF13A,LMBRD1,TMCC1,PDZRN3,UNC80,USP33,SON,WDTC1,TNIK,SP2,TEX2,TSPYL2,LHPP,TAB2,CLASP2,SMOC1,ZC4H2,LARP4,ERBIN,ELOVL4,KANK1,SULF2,SEPT3,NECAB1,FGD4,VAMP1,ARHGEF9,ANKRD28,SYT5,POPDC3,MTCL1,CAMSAP2,PDLIM2,UNC5D,ADGRL3,SMG6,KLHL4,EHBP1,TCF4,DMXL2,CUX2,TCF7L2,ZEB1,TRIM2,RPGRIP1L,USP22,FRYL,SIRT1,AP4E1,HHIP,SLC44A1,TJP1,R3HDM1,C5orf64,NPL,AMACR,TSC1,ANO5,SSBP2,TTTY15,TTC3,TMEFF2,FAM181B,VLDLR,WNT7A,RICTOR,PCDH20,ZNF17,FMN2,TMEM237,ZSCAN26,FTSJ1,PRDM2,RNF103,HPS4,PCDH15,GAL3ST3,SNX27,KCNAB1,TRIM16L,MPPE1,MVB12B,EPM2A,DNAH10,FZD3,DOCK8,HNRNPA3,FBXO36,VANGL2,TTC7A,NETO1,RNF146" MicroRNA hsa-miR-936:mirSVR_lowEffct hsa-miR-936:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.66E-150 3.74E-146 1.60E-148 1.47E-147 397 1714 "ABR,ASPHD1,ACADM,ASIC1,CSMD3,NDRG3,TMEM132B,TMCC3,AXIN2,CDC7,ADRA1D,SLC44A5,MTUS1,KLHL13,RTL9,OSBPL1A,HFM1,GOLGA7B,DPP10,ANK2,ANK3,CCDC146,APBA2,MAGEE2,UPRT,USP37,AQP4,CDC14B,MADD,ZFYVE28,NUMB,ALDH4A1,MTMR9,TTLL9,BBS2,KSR1,FUBP1,LINC00906,SCAPER,CACNA1G,C5,GPC2,IL33,MMD2,CACNB2,KALRN,CAMK2A,CANX,CAPN3,CBFA2T2,C1orf52,LRBA,REPS2,CDC42,LRRFIP1,LOC730101,DLGAP1,ADGRG1,MS4A7,CLCN4,CLTA,SRP14-AS1,MAP4K4,NIPBL,ARHGEF6,PCYT1B,ARMC8,COL4A5,ABI3BP,MYRIP,ZFP28,CNRIP1,SNCAIP,FEZ2,OSBPL3,CST3,APPL1,PHF14,CTH,DCAF4,CCDC144A,KATNAL2,PHYHIP,TOMM20,GIT2,PITPNC1,ARMCX2,C8orf34,DGCR5,ZEB2,ZC3H11A,PLPPR4,G3BP2,SEC16A,DMD,NR1D2,FAM57B,DRP2,DTNA,DNAJB6,DYRK1A,SEZ6L2,HEYL,SUGP2,MRO,EIF4G2,EPB41L2,EPHA5,EPHB1,GPHN,STX2,CEP85L,ETV1,SIRPB1,EXTL2,EYA1,HSPA12B,FAM198B,AMZ2,ST3GAL6,ZSCAN30,ZNF589,GORAB,FER,FGF1,SPSB4,FGF13,FGF14,CAMSAP1,FHL1,POLK,UBE2E3,CAP2,PCYOX1,SEMA4D,FLT1,PSD2,EFCAB2,TACC2,TMEM107,HVCN1,UFM1,ATP2C1,ERGIC3,DACH2,KBTBD12,NRG3,HRASLS5,GALNT15,GABRG1,GALC,RAPGEF6,NCKAP1,ERAP1,ATP8A2,ACSS1,KIAA1841,DNER,GATM,NEU3,GCNT2,TUBGCP4,SULT1C4,LYVE1,PCDH11X,MAP7D2,LUZP2,FERMT2,PSRC1,ATF7,STON1,LPAR4,EML4,GPR37,GRID1,GRIN2C,GRM3,ZNF496,KIF3A,KAT7,AP4S1,MAEL,RASSF8,HPS5,TNFAIP8L3,HMGB1,C9orf129,ZDHHC15,NEGR1,DHX35,IGF1,C5orf24,RBPJ,TJAP1,BRINP3,KCNA1,KCNC2,KCND3,KCNJ5,KCNJ11,KCNK1,KIF5C,A1BG-AS1,KLC1,STMN1,PAXBP1,SYTL4,SMAD1,MARK1,MATN3,MEIS2,XRRA1,MMP16,MOG,MRPL42,ADAM22,CTNNA3,MX1,RTL5,NODAL,DNHD1,NPTX1,SMIM11A,NTRK2,CLDN11,P2RX7,SNTG1,PAX6,PDYN,SLC10A4,GNG2,PFKFB3,CDK14,SERPINE2,PIK3C2A,ANLN,PIK3CD,PIK3R1,ZNF655,CCSER2,PLEC,PCDH18,SMIM7,PURG,PDZRN4,TRHDE,POLG,PPP2R5C,KANSL1,PRKCB,MAPK9,RELN,CNNM2,BCAS3,VPS13C,SLC22A23,APTX,SIDT1,MDGA2,PTAFR,PTCH1,MTMR10,PTN,PTPRB,PTPRG,NKAIN1,TUG1,ZNF844,PPP2R3C,ZNF793,RALGDS,FAT4,KHDRBS2,RDX,ZYG11B,ZMAT4,RET,RFX4,RNF220,SLC25A36,RPRD1A,ROBO2,RORB,SPIN3,ZC3H14,LRRK2,ABCA11P,ATAT1,FAM192A,SAFB,SARS,ATXN2,ATXN7,LRFN5,LRRTM4,SCN8A,SCP2,SOX6,COPZ1,KIF16B,MYO18A,NTNG1,FNDC3A,CTXN2,DZIP1,ANKRD6,FAM81A,LRRC55,SLC6A8,SHANK2,SLC15A2,ELMO2,SPHKAP,SLIT1,CDK5RAP2,ANKRD36,MAPKBP1,MBD5,WDTC1,DOK5,KDM3A,CLUAP1,EMC1,ZBTB43,NPAS3,C11orf87,COLGALT2,THSD1,KANK1,SYT11,FGD4,PLCB1,SYT1,FBXW11,VWA3A,EHBP1,ACSL6,TPCN2,SZT2,WDR7,SYNE1,PCDHB3,TNS2,GPRIN3,TEX15,ZFPM2,C18orf54,TIAM1,NACC2,TJP1,DDHD1,TMPO,FAM124A,RIMBP2,SYNPO2,STXBP4,TRPS1,TSN,TTTY15,HEPACAM,UCHL1,UGT8,USP1,BCL2L13,VLDLR,LMF1,VSNL1,SLC13A3,ZIC3,ZNF711,ZNF24,ELFN1,ZNF74,PLPP4,SLC26A10,LYPD6,ZNF138,FSTL5,PLPPR5,DHX33,WNK1,STMN4,RNF103,SCG2,NAV3,FAM47E,RGS7BP,AMN1,UBE3B,HNRNPA3,PHTF2,CASC15,SSPN,PIANP,FXR1,DPF3,CPNE4" MicroRNA hsa-miR-561:PITA hsa-miR-561:PITA_TOP PITA 6.80E-150 3.82E-146 1.63E-148 1.50E-147 300 968 "ACTN2,XKR4,CSMD3,SLITRK1,CCDC85A,ADD3,PWWP2A,SNX30,NLGN4X,GPR158,HECW2,NR0B1,ALCAM,FAM135A,LRFN1,APC,EPB41L5,API5,USP37,CDC14B,SLC7A14,PPP4R4,CASK,ARHGAP5,ASCL1,ZSCAN18,DDX3Y,TMEM108,SLC4A4,STX16,NOL4,DPY19L3,ADGRB3,SYNJ1,ST3GAL5,MTMR2,WASF1,CA8,CAMK2A,SYT6,CAST,BRSK2,SPAG9,CBLN1,LDB2,CCNH,AP4M1,SEPT7,ZMYM4,CACNA2D2,FOXN3,SOCS6,KMT2C,NRXN1,NRXN2,QKI,HECTD1,NIPBL,CNTN1,ZNF521,CRHBP,HAPLN1,TENM4,LRRC3B,CSNK1G3,SOCS5,PPP1R16B,CTNND2,RIMS2,LONRF1,IST1,SPOCK2,SIRPA,PITPNC1,ZEB2,MYEF2,MFAP3L,MAGI2,RHOBTB1,SNAP91,SACS,DLG2,DLX1,NR1D2,CPEB2,ABI1,PDCD6IP,MAMLD1,GOLT1B,RBM12,SH3GLB1,CELSR3,MBNL2,GOLGA7,ELAVL2,ELAVL4,TMEM35A,PAN3,EIF1,EMX2,RCAN2,RRAGB,CACNG2,TAOK3,SCML2,ATP8A1,TESK2,FECH,MED12L,ANKFY1,NBEA,SORBS1,FAM49B,NPTN,KHDRBS3,DACH2,CSPG5,MSANTD4,PHYHIPL,STAG2,MEGF10,GABRA5,GABRB3,AHCYL1,ERAP1,GATM,GHR,TCERG1,GLRB,FERMT2,GPD2,EML4,CECR2,GRB10,GRIA2,GRIA4,CIT,RNF165,LINGO1,ADAMTS6,ZHX1,MIER3,HLF,ELOVL5,HNF4G,HNRNPK,CFAP126,IGF1,NKD1,RBPJ,LRRTM3,LRRTM1,KCND2,KCNK1,KCNN2,KIF5C,STXBP5,LIFR,SMAD1,MATN3,MBP,CHIC1,LRP1B,MEST,KITLG,MITF,AFDN,MN1,CCDC80,MYCN,MYH3,MYO5A,NEXMIF,NCAM1,ZC3H12B,NF1,NFE2L2,HCN1,OMG,PDE3A,CCSER2,FAM216A,PLP1,PURG,STRN3,PRRX1,FAT3,POU3F2,MED1,PPP2R2B,LRRN3,PPP3CA,PRKAB2,PKIA,PKN2,QRICH1,PTCH1,PTPRD,FAM120C,RAB5B,USP47,ARID4A,RBBP6,KHDRBS2,RGS4,RIC8B,ZFHX4,LGI2,CARF,ROBO1,ROBO2,FBXW7,MCMBP,ATP8B4,SOX8,KCNIP3,ZNF331,RMI1,ATXN2,SCN3A,SMPD3,SOX6,SCAF8,NLGN4Y,CPEB3,FNDC3A,CCDC92,WDR37,PPP4R3A,WDR47,SLC8A2,YPEL4,CCDC88A,KBTBD4,SLC12A2,CPEB4,RCOR3,SNAP25,FAM126B,SOX1,MYT1L,SOX2,SOX5,FNBP1,SOX11,ZHX3,SP4,CDK19,SRPK2,POGZ,STAU1,TTBK2,RGL1,NECAB1,PRRC2C,SYPL1,ANKRD28,POPDC3,ANKRD12,CAMTA1,CNTN2,ADGRL3,EHBP1,SATB2,TCF7,TRIM2,PSD3,ARHGEF12,FRYL,SIRT1,ZFPM2,ITGB3BP,SLC44A1,TIAM1,TJP1,NR2E1,ERCC6L2,TP53BP2,TPM3,PDSS1,TRPS1,TSC1,TUB,HEPACAM,UCHL1,VLDLR,NSD2,LYPD6,CELF4,ZFAND5,WNK1,PRDM8,SNX27,SLC17A6,HNRNPA3,PHTF2,ADAMTSL3,FXR1,NETO2,SLC4A10" MicroRNA hsa-miR-137:mirSVR_lowEffct hsa-miR-137:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.96E-150 3.91E-146 1.66E-148 1.53E-147 386 1622 "SYN3,AS3MT,ACTN2,CSMD2,TMEM132B,ELFN2,CCDC85A,RNF157,BRAP,SLC12A5,PWWP2A,KIAA1211,RNF150,NLGN4X,MTA3,SLC24A4,GPR158,HECW2,KCTD16,OSBPL1A,NR0B1,OSBPL8,CC2D2A,HFM1,ARHGAP20,FAM135A,ANK3,USP28,KCNAB2,MAGEE2,GPAM,API5,ARHGAP5,CDK13,CAPRIN2,NCOA1,ATP2A2,N4BP2L1,ATP6V0A1,BACH1,BBS2,MPDZ,MIR9-3HG,DCAF5,BID,SYNJ1,FUBP1,SGCE,IL33,CACNB2,VSTM2A,MAP7,CCNH,C1orf52,CDC42,L3MBTL4,CLGN,SOCS6,CHM,RAB3C,B4GALT6,TPP1,NMT2,CLTA,FHL5,PCYT1B,AKAP6,LETMD1,RTTN,TOGARAM2,ZNF521,PREPL,C2CD2,CREM,CRHBP,SEC24C,ARHGEF10,OSBPL3,ATRNL1,RIMS4,PDE4DIP,CNTNAP2,ERC2,CTH,CTNND1,NRSN1,PPP6R2,ARHGAP32,FGFR1OP2,DCAF8,MATR3,RIMS3,DGKG,TMEM170A,DBN1,YTHDC1,JAKMIP2,MFAP3L,POM121,SNAP91,SPOCK3,SV2A,SRGAP3,WDR20,DYNC1I1,DMTF1,SLC12A6,ABI1,WDPCP,EDNRA,ATL1,TMTC1,EFNA3,FAM13A,MRO,KMT5B,ABI2,EGR3,GOLGA7,EIF4G2,ELAVL4,PCOLCE2,C8orf37,USPL1,EIF1,EMX2,COQ7,EPHA5,GPHN,MRPL37,ABCA8,SH3YL1,TAOK3,DLC1,ATP8A1,FKTN,TESK2,GORAB,MED12L,FGF1,FGF11,PRKAG2,POLK,IP6K2,SEMA4D,SGIP1,SMC2,FAM49B,NSG1,STAU2,PNMA2,FYN,GABRG2,HBS1L,ZNF234,MTHFD2,CPLX1,GATM,SESN1,AHDC1,GFRA2,HEPN1,COPS8,SPIN1,TOX3,PRUNE2,GPR22,GPR37,PCLO,CACFD1,GRM3,GRM8,LINC01089,PSIP1,GUCY1A2,GUCY1A1,FRMD3,MIER3,ZNF491,NEGR1,SHISA6,HTR5A,IGF1,C5orf24,LIX1,IL6R,ITGAV,C2CD4C,KCNA1,OLFM3,CDH20,KLHL23,KCNK1,KCNK2,CYP27C1,INSYN2,PAXBP1,LMO2,SYTL4,HECTD2,MARK3,MBD1,CHIC1,EFHB,MEF2C,MEIS1,WDR49,SCG3,MXI1,MYH3,ZNF862,BEX5,NAP1L2,NEK1,NFIX,SLC11A2,NRDC,OCRL,OPCML,CLDN11,PAH,PCDH8,PCDH9,PRTG,PDE3B,PDE4A,PDE4D,SERPINI1,CCSER2,SNX10,GPSM2,MAPKAP1,RETREG2,PILRA,SH3KBP1,POU3F2,PPP2R2B,PPP2R5C,PPP5C,PRKCB,EPDR1,DCHS2,SAMD9,SLC22A23,GON4L,SNRK,PIGG,PTK2,PTPN13,PTPRB,PTPRO,RIPOR1,MARCH1,PID1,CEP97,RAD52,FAM66C,ENOX1,RASGRF1,RBBP6,SLC6A15,REV3L,RGS4,RGS7,TTLL7,RLBP1,RIC8B,LGI2,ROBO1,ROBO2,CCDC102B,RPL15,MCMBP,TCP11L1,YJEFN3,SATB1,ATXN2,PEAR1,SEC14L1,SOX6,NLGN4Y,SGK1,PPM1E,FERMT1,DOCK10,MAGI3,FBXO11,NLGN1,ST3GAL3,CTXN2,DZIP1,NUBPL,FAM81A,SLC6A1,SEPHS1,RAB3GAP1,LGI3,SORCS3,RCOR3,MBD5,SNRPN,TMCC1,PDZRN3,SON,SOX5,SOX11,DOK5,HECW1,MYCBP2,KDM4C,SPTB,TSPYL2,NPAS3,NFASC,SRPK2,TAB2,ZNF621,ATP10B,ITPRID2,EPB41L3,NKAIN2,LRRC4,ELOVL4,SEPT3,FAM168A,MLC1,NUDT10,ANKRD28,POPDC3,DDHD2,DNMBP,ALG1,MGRN1,TBX15,TCF4,TCF7L2,TPCN2,DOCK9,PCDHB10,ARHGEF12,DICER1,CRB1,ZNF106,THBS4,GZF1,TIAM1,RELL2,TMOD1,KAT6B,SYNPO2,TRPC3,TRPS1,TMEFF2,AMOT,DNAJC12,FLRT2,PLEKHH2,ZNF709,MGAT5B,VLDLR,CLDND1,GUSBP1,XRCC4,ZNF24,ZNF28,FMN2,GPR158-AS1,LYPD6,SPHK2,ZNF177,ZNF189,FTSJ1,ZFAND5,DHX33,LRP8,SLC38A1,SEMA3B,PCDH15,GAL3ST3,FIP1L1,C12orf4,ST7,CASC15,FXR1,NETO1,SLC4A10" MicroRNA hsa-miR-194*:mirSVR_lowEffct hsa-miR-194*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.76E-150 4.36E-146 1.84E-148 1.69E-147 427 1975 "VWA5B2,ACADM,SYS1,GPRIN1,ADAR,SLITRK1,TMCC3,ADD1,UNC5A,NLGN4X,KIAA1324,CC2D2A,PLA2G6,SEMA6A,LTBP4,FAM135A,ZNF687,LRFN1,EP400,PI16,CCDC146,PPFIA1,CNTNAP1,APBB1,KCNAB2,APLP1,MAGEE2,DDO,PPFIA3,CDK10,KIAA1614,SEMA4G,CADPS,CAPRIN2,ASPH,RASL11B,ASTN1,ATP2B1,ATP2B3,DPY19L3,KIF1A,ADAM23,RGS11,NRP2,BID,CFLAR,FUBP1,MTMR3,CACNA1G,WASF1,CDK5R2,BTRC,CA4,CA8,CACNA1B,CACNA1D,DDR1,CACNA2D1,CACNB2,CACNG1,THSD7A,TRIM41,CERS5,MTMR7,P2RX6,TMEM257,REPS2,CDC27,LRRFIP1,CRLF1,ASIC3,CHM,CHRNB2,KMT2C,NRXN3,PPT2,DNAJB5,CNN3,FAM149A,COL11A2,COX4I1,SLC35F1,PNKD,CRY2,CLIP3,LRRC3B,CSNK1E,OSBPL3,ATRNL1,GALNT9,SOCS5,UBXN2A,CTNND1,MYADM,FGFR1OP2,KATNAL2,TBC1D5,LIN54,IP6K1,AIF1L,ZEB2,PLEKHM1,ELMO1,KIAA0753,MAGI2,ZC3H11A,POM121,PLPPR4,NTM,SGSM2,GRIN3A,DYNC1I1,CDON,SLC12A6,DPYSL2,DRP2,TOM1,DUSP9,DYRK1A,ABCC5,USH1C,FAM135B,RBM12,EFNB3,GPR61,EGFR,AASS,EIF4G2,EIF5,PLEKHA1,ING4,BSCL2,ELN,VPS13B,EPHB1,ANKRD13B,SLC43A2,SRRM1,IGSF6,HSPA12B,NRN1,F5,NSRP1,TOMM40L,FCGRT,ZSCAN30,OLFM1,SPSB4,FGF14,MAD2L2,FHL1,SUCO,C1orf61,IP6K2,SEMA4D,SGIP1,NOP56,FLYWCH1,NELFCD,AKAP3,NBEA,TPK1,RASL10A,CAMKK2,NSG2,ST6GALNAC3,B3GAT1,ADGRA1,TPPP3,AP4B1,NRG3,ZNF512,STAG2,DKK3,GABBR1,GABRA3,RAPGEF6,ARPP21,IQGAP2,C15orf41,SEPT9,TUBA8,ARFIP1,WASHC2A,CYP46A1,CSDC2,DHRS4,GK,TCERG1,GLYR1,INSM2,LUZP2,LOXL3,GNAO1,WDFY3-AS2,PSRC1,CNDP1,GPR17,GPR34,GRB10,GRIA4,PLCD4,RFFL,SERP2,GRM2,GRM7,ZNF496,GSTM5,FAM107A,TOX2,ARHGAP19,ATXN2L,AGBL5,IRF8,MSL1,IL11RA,INPP5B,LRRTM3,ITPKA,ITPKB,KCND1,KCNJ4,KCNJ10,KCNN1,KCNN3,GATD1,KIF5C,INSYN2,MAP6,MAT2A,MBNL1,MDM4,MEST,MOG,CPNE9,SAMD5,MXI1,MYH6,MYO7A,MYO9A,RTL5,NAP1L3,NEUROD1,NEUROD2,SLCO1C1,ALDH1L2,NINJ2,NPTX2,PCBP3,OPA1,OPCML,P2RY1,PCSK1,PDE1C,PDE1B,ENPP2,GPR85,CDK14,ZNF655,PKD1,TMEM38A,KCTD15,PLCL1,PLP1,SLC25A23,PDZRN4,SDK2,IRX1,PPP3CB,PRKCB,EPDR1,GRAMD1C,DIRAS2,KLK6,SLC22A23,SYTL2,MDGA2,PIGG,BDNF-AS,PTK2,PTPRB,PEX2,ZSCAN2,RAB3IL1,ACSS3,RALGDS,BSDC1,RDX,ZYG11B,TRIM68,RET,RFX3,PRIMA1,RNASEL,RNH1,ARMC5,KIRREL1,ROBO2,ELP2,NEK11,FBXW7,BAALC,ZNF671,GLDN,PRR5L,TCP11L1,ATAT1,YJEFN3,KCNIP1,ZNF331,TRAPPC13,HOGA1,FNIP1,ASIC4,PEAR1,TRIM46,ZNF821,GALNT10,SFPQ,FAM102A,SH3GL3,FERMT1,FNDC3A,ANKRD6,WDR37,ZNF365,PREX2,BTBD3,EPN2,LRRC55,SLC6A7,SLC6A8,KDM4D,RAB3GAP1,SIRT2,SLC12A2,ELMO2,SLC20A2,ATF7IP,TET1,CXXC4,MBD5,FAIM2,FAM126B,BDP1,NMNAT2,ENKUR,MYCBP2,KIF1B,CDK19,NFASC,LHPP,STOX1,EPB41L3,NKAIN2,ERBIN,DIP2A,STAC2,ADHFE1,ARHGEF9,VPS13A,SYN2,SLC37A2,TACR1,MTCL1,WWC1,IQCE,KLHL4,ANO4,VWA3A,TCEA1,SATB2,ZFP90,WDR7,PCDHB4,NSD1,HIF3A,CYB561A3,DICER1,TGFBR3,FBXL16,TIE1,RIMBP2,SEZ6L,RASD2,TPM3,WBP2,ZNF384,ZNF346,PRMT8,TRO,TUB,ZKSCAN5,RPRM,CLEC2L,UGT8,OSBP2,VLDLR,NSD2,NPDC1,SLC13A3,LGI4,CFAP298,SLC47A2,ZIC3,ZNF19,ELFN1,LYPD6,TCEAL7,ZSCAN26,UPF3A,WNK1,EMSY,GDPD5,CIAPIN1,SIGLEC10,URM1,ITM2C,DNAH10,MRPL47,UBE3B,SMIM8,NUP214,RNF170,PIANP,NETO1,LAS1L" MicroRNA hsa-miR-1246:mirSVR_lowEffct hsa-miR-1246:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.72E-150 4.90E-146 2.06E-148 1.90E-147 386 1623 "ABAT,NCKAP5,SLC25A25,TMEM132B,KLRC4,TMCC3,DPY19L2P4,PCDH19,OSBPL6,WDR35,CC2D2A,ZNF578,SPARCL1,SMIM17,UNC79,LRFN1,DPP10,ANK1,PARG,PHYHD1,USP37,APP,SHTN1,SLC7A14,ARNTL,PDE8B,MARCH3,MARK4,ASTN1,ATM,ATP1A2,SLC4A4,STX16,MTMR9,ADAM23,BACH1,BBS2,BMP7,SYNJ2,MTMR2,IL33,CACNA1E,KALRN,SLC25A14,SEPT7,REPS2,CDC42,CDH8,LGI1,CHN1,CHRM1,RAB3C,IGFBP7-AS1,CLCN4,MAP4K4,ARHGEF6,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,FAM171B,HAPLN1,SLC32A1,MROH8,SNCAIP,RGS6,LRIG1,LRRC3B,VCAN,PPP1R16B,PHF14,PLCXD3,CTNND2,NRSN1,RIMS2,DCAF4,USP6NL,SEC14L5,GAPVD1,ARHGAP24,DCAF8,TOX,ZFYVE16,EARS2,ZNF337,KIAA0586,SPOCK2,GIT2,DNAL1,YTHDC1,ZNF804A,C8orf34,HP1BP3,KLHL3,ZC3H11A,SV2B,RABGAP1L,WDR20,DLG3,CPEB2,CASP8AP2,DTNA,DNM1L,GOLT1B,WDPCP,EDN1,HIPK3,KLHL5,EGR3,EIF4G2,RGS17,ELN,EN2,DENND4A,NCALD,IGSF6,RCSD1,EYA1,F3,F5,EFEMP1,CEP78,STRADA,GORAB,FECH,SLC9B2,FER,FGF13,CAP2,SEMA4D,SLC37A3,FLYWCH1,FOLH1,SMC2,TRIM16,NPTN,CAMKK2,ATP2C1,KHDRBS3,CELF1,DACH2,OGA,GABRA2,GALNT15,GABRB3,ZMYND11,IQGAP2,ERAP1,DISC1,KIAA1841,IGSF5,MSTN,ADAM28,GFRA2,TOX3,ZNF638,GNAO1,GPM6B,CCDC184,GPR22,GPR37,DIDO1,GRID1,GRIK1,ZNF496,GSN,KIF3A,LINC01551,MUM1,IRAK3,RASSF8,FRMD5,GABARAPL2,AGFG1,IRF8,C2orf72,C5orf24,ZIC5,USP54,LRRTM3,METTL21A,KCNA6,KCNK1,KCNK2,KCNMA1,IPO5,LIG4,LIMS1,ARHGAP12,C2orf80,PIK3AP1,MAN2A2,CHIC1,LDLRAD3,TM6SF1,SRSF12,MEST,MIA2,KITLG,MID1,MMP16,MOBP,MTTP,MXI1,LAYN,BEX5,FXYD6,ZC3H12B,NEUROD1,NFIA,LRIT2,NPTX1,NUCB2,TBC1D25,OCRL,OPHN1,P2RY1,GPR137C,KCNK10,SNTG1,PAK3,CNTN3,PBX1,PCSK5,PDE2A,PDE3B,PDE4D,PIRT,PDGFRA,BEST3,PFKFB3,NLGN3,CCSER2,PLCL1,PLXNB3,PURG,PMP2,PMP22,STRN3,LRP12,NECAB2,ING3,SPATA6,FSD1,POU6F1,PPARA,PPM1B,TATDN3,PPP2R5E,PPP3CB,PRKACB,PKIA,PKN2,MAPK8,HYDIN,DCHS2,SIDT1,SNRK,PTHLH,TMEM260,PTPRD,RAB5B,TMEM255A,USP47,FAM66C,RALGDS,DBX2,PRRT2,RFX5,RGR,SLC25A36,PBRM1,RNASEL,CCDC82,SETD5,RAVER2,TMEM100,NEK11,TCP11L1,RPS6KA2,LRRK2,ATAT1,NCBP3,SEMA6D,SCN4B,FAM19A1,SCP2,SLC30A10,ZFP2,ASRGL1,TRA2B,SCAF8,NLGN4Y,ITSN1,PPP1R9A,SH3GL2,SH3GL3,KIF16B,HKDC1,CHD9,FHOD3,SLC6A1,KANSL3,RAB3GAP1,SLC20A2,ATF7IP,SPHKAP,GKAP1,MAST1,ANKRD36,SNAP25,MBD5,SNRPN,MYO16,PDZD2,TRERF1,ZCCHC24,BDP1,SP2,ENKUR,UHRF1BP1L,UNC5B,PEG10,ZNF423,KIF1B,NFASC,C11orf87,LARP4,ADHFE1,KLHL7,FGD4,SYNE2,VPS13A,SYN1,TACC1,PJA1,TCEA1,ACSL6,VWC2,TCF4,SATB2,RPGRIP1L,DOCK9,PCDHB9,SIK3,ZFPM2,TGFBR3,FAM124A,RIMBP2,WBP2,SYNPO2,STXBP4,TRPS1,ZMYND8,ANO5,RFTN2,MGAT5B,WIPF1,RICTOR,XRCC4,ZIC2,ZNF708,ZNF28,ZSCAN26,ANKS1B,SLC30A4,EMSY,CADM2,CSDE1,TRIM16L,WNK3,PARP11,EPM2A,RGS7BP,FZD3,DOCK8,PAK5,CERS6,ACTR3B,ADAMTSL3,SSPN,NETO1,SOCS4,CPNE4,SPATA13" MicroRNA hsa-miR-222:mirSVR_lowEffct hsa-miR-222:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-149 5.74E-146 2.40E-148 2.21E-147 359 1405 "CPNE2,CLK4,NCKAP5,SYS1,NDRG3,TMEM132B,TMCC3,ADD3,PTCHD1,BEND6,SLC24A4,OSBPL8,LRRC7,SMIM17,CEP126,BBOX1,AMPD3,LRCH2,MAP4K3,USP28,PHF12,PKP4,GPAM,SHTN1,SEMA4G,TMEFF1,STK33,ASTN1,DDX3Y,INSYN2B,ATP1A1,ATP2A2,KSR1,SYNJ1,ARHGEF7,SCAPER,MTMR3,NIPA1,OSGIN2,CALM1,PTBP2,LDB2,AIFM1,CD38,CDH2,LARGE1,SRSF11,CHGB,CHM,CHN2,SYNPR,NRXN3,NRXN1,FBXO7,AKAP6,SLC4A8,ABI3BP,ZNF521,CNRIP1,MFSD4A,CP,ZNF385A,CPS1,RBM39,CRHBP,NCOR1,CSF1,ARHGEF10,OSBPL3,SUSD5,ATRNL1,SOCS5,SLITRK5,UBXN2A,PLCXD3,CTNND2,NRSN1,MATR3,RIMS3,MAML1,BRINP1,DBN1,YTHDC1,C8orf34,DGCR5,CEP170,DDX46,SGSM2,DLG2,DLX1,DYNC1I1,CDON,DMTF1,CASP8AP2,DTNA,DNAJB6,ABCC5,DNM1L,E2F5,WDPCP,HIPK3,RASGRP1,KLHL5,FRY,YAF2,FAM13A,EIF5,EIF1,RCAN2,KCNMB2,ERBB4,DENND4A,RRAGB,F3,FAM198B,TMEM132C,CEP78,FKTN,GTF2IRD2,KIAA1109,FGF14,UBE2E3,MEX3B,FOXG1,SYNCRIP,FOXO3,SLC37A3,STAMBP,CGREF1,GAB1,GABRB1,GABRG1,IGSF5,TCERG1,RNPS1,GLI2,GLRB,TNRC6A,PCDH11X,ZNF638,GNAO1,PRRC2B,PRUNE2,GPM6B,ATF7,GPR12,NUDT21,GRB10,PLCD4,GRM1,CIT,TMEM25,LINC01551,WIF1,ZHX1,FRMD5,HLF,AGBL5,HNF4G,HNRNPK,NEGR1,OPALIN,AGFG1,MYLK2,IGF1,C5orf24,DOCK7,USP54,IL11RA,RIPPLY2,INPP5B,SLC6A17,ZNF385B,KCNC2,KCNJ16,KCNMA1,KCNQ3,CREG2,IPO5,CYP27C1,MAP6,ADAM11,MDM4,MEST,KCTD6,MITF,AFF1,MOBP,ERICH3,COL28A1,MTTP,ZNF862,NAP1L1,NCAM1,SLCO1C1,CNOT4,NRCAM,NTRK2,NUMA1,TBC1D25,ODF2,OGG1,ZNF713,GLIPR1L2,DPY19L2P2,ETFRF1,PCDH8,PCDH9,PCSK1,PDGFRA,OLA1,CDK14,PIK3R1,ZNF655,HMGCLL1,LRP12,POU3F2,PPM1B,PTPA,PPP2R5C,KANSL1,PRKAB2,DIRAS2,GDPD1,CNTLN,PTK2,PTPN13,OCIAD1,EML5,PTPRH,C1orf109,PTPRZ1,PTX3,RAB3A,USP47,ENOX1,RBBP6,RBBP8,MSANTD2,SLC6A15,REV3L,GTDC1,FIGN,LGI2,TMLHE,C12orf49,LGR4,RTN1,MIR124-2HG,SEMA6D,SATB1,ATXN1,ASIC4,ASRGL1,KIF21A,ITSN1,PPP1R9A,NTNG1,FHOD3,ST6GAL1,SLITRK3,ST8SIA1,PAAF1,RPH3A,SLC6A11,SEPHS1,SLC11A1,ATF7IP,SLN,SMARCE1,ANKRD36,SNAP25,SNCB,MYO16,UNC80,USP33,SOX1,BDP1,SOX11,KDM3A,SPP1,IDI2-AS1,CDK19,SRPK2,ITPRID2,NEK4,SEPT8,RGL1,STX1A,SULF2,AJAP1,GSE1,FNDC9,C3orf70,PLCB1,SYPL1,SYT1,TACR1,DNMBP,PDLIM2,ADGRL3,KLHL4,ANO4,EHBP1,CUX2,TCF7L2,TRIM2,WASHC4,FRYL,CCDC173,SIK3,RNF216P1,PMS2CL,DICER1,SIRT1,CRB1,C18orf54,GPR161,GZF1,TIAM1,TMPO,RIMBP2,KCTD2,KAT6B,TPM3,STXBP4,TRPC1,TTPA,TUB,AMOT,UGT8,PITPNB,ZNF781,CLDND1,XRCC4,ZBTB14,ZNF24,ZNF74,TMEM237,AMZ1,ANKS1B,ZFAND5,PMEPA1,EMSY,MFF,LRP8,STOX2,PRDM10,ADAMTS9,PCDH15,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,FAM219B,RSPRY1,SOCS4,SENP7" MicroRNA hsa-miR-1255a:mirSVR_lowEffct hsa-miR-1255a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-149 7.91E-146 3.30E-148 3.04E-147 396 1709 "ABAT,DGCR6,ASIC1,SYS1,ACTN2,GALNT16,KLRC4,BRAP,SLC12A5,CDC7,GRAMD1B,PTCHD1,ZNF578,C1QTNF3,LRRC7,FAM135A,AMPD3,LRFN1,OGT,MAP4K3,USP28,PPFIA4,PKP4,CNTNAP1,APAF1,DGKZ,UPRT,PHYHD1,CPNE5,SPTBN4,MARCH3,ZBTB10,NCOA1,DDX3Y,ATM,STX16,ZNF583,B3GALT2,ATP6V0A1,TTLL9,AZGP1,BID,DST,ARHGEF7,SCAPER,SGCE,OSGIN2,CFAP410,CACNA1B,CACNA1E,CACNB4,CAPN3,SPAG9,CBR1,CD86,ENTPD2,ARHGEF2,LRRFIP1,TIGD7,CLGN,DIS3L,SRSF11,CHM,JAM2,TAOK2,PPT2,DGCR9,CLTA,TJP2,SRP14-AS1,CNGA3,FHL5,CNN3,BTF3L4,IFFO1,AHCTF1,MYRIP,CNRIP1,CHD1L,CPS1,FAM171B,MROH8,SOCS5,PDE4DIP,CNTNAP2,CMTM5,PHF14,CFAP61,NRSN1,FAM131B,CX3CR1,RIPOR2,HDAC4,TMEM170A,AIF1L,PITPNC1,ARMCX2,MFAP3L,C2CD2L,SGSM2,WDR20,ZNF582-AS1,DMTF1,CASP8AP2,DRD1,PDCD6IP,DTNA,TOM1,ABCC5,ABCC9,GOLT1B,E2F5,WDPCP,EDNRB,SYT15,FSD1L,EFNB3,MBNL2,ABI2,RASA4,TMEM35A,STARD3NL,OLIG2,ENO2,EPB41L1,COQ7,KCNMB2,GPHN,STX2,DENND4A,CDHR1,RCSD1,ADGRV1,GMPR2,CORO2B,CEP78,TOMM40L,FDFT1,KAT8,FER,FGF12,FGF13,FGR,CAMSAP1,FOXO3,SLC37A3,NOP56,AKAP3,DPYSL4,NBEA,UFM1,TPK1,ATP2C1,DLL3,STAU2,ABLIM2,ZNF512,MEGF10,GAB1,JPH4,ZNF559,DISC1,GATM,GCK,SRCAP,MSTN,GPR162,GFAP,GGTA1P,PPARGC1A,RUNDC3A,ZNF276,CRCP,TCERG1,RNPS1,STARD3,KDM2B,POLL,GNAO1,GNG3,GPM6A,LILRA2,NUDT21,PCLO,DIDO1,GRM2,GRM5,GRM7,ZBTB49,FAM107A,SLC2A6,WIF1,NXPH3,BACH2,MIER3,HMGB1,SYNPO,ZNF491,TLX1,CPT1C,OPALIN,SHISA6,SMAP1,ICA1,C5orf24,IGFBP1,USP54,SLC35G1,METTL21A,KCNJ11,KCNK1,STXBP5,KTN1,LAMP2,STMN1,INSYN2,LIFR,LIMS1,NCOA7,PIK3AP1,MAPT,MATN2,MATN3,SYT9,LDLRAD3,TM6SF1,AFDN,MPP2,DBNL,COMMD5,PTOV1,MTTP,MTR,MXI1,MYO6,MYO7A,MYO9A,NEXMIF,FXYD7,FXYD6,NEK1,NELL2,NEUROD1,NFE2L2,NRCAM,SMIM11A,NTRK2,NUCB2,OCRL,OGG1,PCDH9,PCMT1,PDE4A,PDGFRA,PFKFB2,SEMA5B,SNX10,NLE1,PLIN1,HMGCLL1,MTRF1L,PNMA3,SDK2,MAGEL2,TNPO2,POU6F1,PTPA,PPP2R5C,PRKACB,PRKCB,PRKCZ,GRAMD1C,MASP1,VPS13C,PIGG,MTMR10,PTHLH,OCIAD1,PTPRD,FAM120C,PEX5,ZSCAN2,RALGDS,IQSEC3,RAP1GDS1,MSANTD2,PRRT2,ARHGEF10L,RNASE1,NUDT11,RPRD1A,LGI2,TMLHE,ROBO1,RORB,ATP8B4,ATAT1,KCNIP2,NCBP3,FAM192A,TNFRSF19,SOX6,SCAF8,FAM102A,ASAP3,DZIP1,ANKRD6,WDR37,LRRC55,SLC12A2,ELMO2,SLC22A4,NAXD,GKAP1,SORCS3,CDK5RAP2,SNAP25,FAIM2,SNRPN,UNC80,WDTC1,ZCCHC24,TSNAXIP1,SOX10,KDM3A,ENKUR,KIF1B,IQSEC2,TSPYL2,RAP1GAP2,C11orf87,TROVE2,POGZ,ITPRID2,STOX1,MAPK8IP3,STX1A,KANK1,JMJD6,ARHGEF9,FNDC9,SYP,SLC37A2,TAL1,ANO4,VWA3A,SIN3B,ZEB1,DOCK9,PUM2,FRYL,CRB1,ITGB3BP,AP4E1,ENHO,MTMR14,ZFP91,TMPO,DAAM2,FAM124A,CSMD1,TPM2,C9orf85,RGMB,STXBP4,TRPM2,TSC1,HSPBP1,HEPACAM,BCL2L13,VAV2,VLDLR,BEST1,NSD2,GUSBP1,XPO1,ZNF24,NDRG4,SLC26A10,TCEAL7,REEP1,DNALI1,LRP8,LINC02210,VPS35L,PCDH15,PPP1R3F,C12orf4,FAM13C,FZD3,UBE3B,KAT6A,CERS6,RNF170,ZNF30,JPH3" MicroRNA hsa-miR-487a:mirSVR_lowEffct hsa-miR-487a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.70E-149 9.56E-146 3.97E-148 3.65E-147 389 1651 "KCNH8,ACADM,SYS1,ARID1A,FMNL2,PSMG3-AS1,PLEKHH1,RNF150,KCTD16,OSBPL1A,KIAA1324,ALAD,SPARCL1,ALCAM,BCAR3,FAM135A,AMPD3,AMT,DPP10,LRCH2,ANK3,MAP4K3,CNIH2,APAF1,APC,GPAM,CACHD1,API5,SHTN1,SHROOM2,AQP4,CASK,ARNTL,CADPS,ASPH,NCOA1,DDX3Y,TMEM108,ATP2A2,DPY19L3,ADGRB3,MIR9-3HG,DST,SCAPER,MTMR2,IL33,CACNB4,KALRN,SLC25A14,PRC1,MTMR7,SLC16A4,SEPT7,CDC42,CDO1,FOXN3,CHGA,CHN2,SYNPR,B4GALT6,NDST3,KMT2C,RAB33A,NRXN3,CLCN3,COG1,C4orf33,QKI,NIPBL,AKAP7,AKAP6,COL4A5,LETMD1,ABI3BP,ACBD5,ZNF521,MFSD4A,CLOCK,PDE4DIP,CTNND2,PUM1,ZSCAN23,CCDC144A,KIAA0408,GPRASP1,ARHGAP32,RIPOR2,PHF19,ZNF337,MAML1,HEPH,CNIH3,KIAA0753,CEP170,DDX46,ALKBH8,SNAP91,RABGAP1L,ZNF582-AS1,CHRDL1,DLG2,DLX1,DMTF1,DSCAM,ECM2,EDNRB,ATL1,SYT15,SEMA3D,OPTN,GPR61,MBNL2,ABI2,EGR3,ASB3,EIF4G2,TENM1,EPB41L2,LRRC23,KCNMB2,DENND4A,CEP85L,TMEM74,ETV1,NRN1,CLVS1,NSRP1,WAC,ZNF585B,RPS6KC1,ZSCAN30,FDFT1,SEC24B,FER,MED12L,FGF11,FGF12,FGF13,UBE2E3,IP6K2,SYNCRIP,AGAP3,FOXO3,NBEA,TPK1,CAMKK2,ST6GALNAC3,STAU2,FYB1,ZMAT1,STAG2,MEGF10,GAB1,CHL1,GABRB1,GABRG1,GABRG2,FAM184B,HBS1L,TMEM8B,C15orf41,DISC1,CPLX2,DNER,MMADHC,USP19,GHR,TTBK1,SPIN1,TOX3,PCDH11X,LUZP2,KCNMB4,FERMT2,ADGRA3,PRUNE2,GPR12,STON1,STMN2,CACFD1,ADAMTS8,GRM5,WIF1,MAEL,RASSF8,TOX2,HMGCL,HNRNPK,AGFG1,DHX35,C5orf24,NKD1,DOCK7,PLD5,LIX1,ZNF678,ZNF385B,ITPKB,KCNA2,KCNJ3,KTN1,PAXBP1,NCOA7,MARK1,MDM4,LRP1B,MEIS2,COL28A1,N6AMT1,MTTP,MXI1,MYCN,NCAM2,NEK1,NFYA,NODAL,CNOT4,NOVA1,NUCB2,CHAMP1,OXTR,PCSK2,PDGFRA,CDK14,ABCB1,NALCN,PIK3C2A,FAM218A,ZFYVE21,GPSM2,PURG,MAPKAP1,LRP12,SCHIP1,ING3,NXPH1,SH3KBP1,PTPA,KANSL1,RANBP3L,PRKAB2,PRKCB,PKN2,PROX1,GDPD1,RELN,BCAS3,WBP1L,SYTL2,SIDT1,MDGA2,QRICH1,WDR25,CNTLN,PTCH1,TMEM260,PEX2,PEX5,PPP2R3C,RAB5B,TMEM255A,FAM66C,SH3TC2,RAP1GDS1,KHDRBS2,SLC6A15,TRIM68,ERI2,GTDC1,RFX4,UBR7,RGS4,RGS7,RIC8B,RNASEL,RPRD1A,GSTCD,NEK11,ATP8B4,RPL38,RPS6KA2,PTGR2,FAM182A,SATB1,CSRNP3,SCP2,ELMOD1,CPEB3,SHMT2,AMBRA1,FBXO11,ST3GAL3,SEC31A,NUBPL,SLA,ZNF365,PREX2,RUFY2,SLC6A1,SLC8A1,SLC15A2,BTBD7,SLCO1A2,LGI3,SMARCE1,RIMS1,CABCOCO1,TMCC1,UNC80,USP33,DOP1A,SOX2,BDP1,SOX11,DOK5,KIF1B,SPART,ATP10B,THSD1,NKAIN2,LRRC4,CEP68,RGL1,KLHL7,FGD4,PLCB1,SYN2,KAZN,EXOC7,CNTN2,TBCEL,TMEM136,TBX15,EHBP1,ZFP90,WASHC4,RALYL,SLC19A3,NSD1,GPRIN3,SIK3,ZFPM2,SLC44A1,TIAM1,TK2,BEX4,TPD52,TPM1,C9orf85,SYNPO2,ZMYND8,TSN,CADM1,PITPNB,PLEKHH2,VLDLR,TBC1D15,P2RY12,ETNPPL,XRCC4,PCDH20,ZIC2,ZIC3,TRIM9,GPR158-AS1,ZBTB38,SPIRE1,UPF3A,DHX33,CADM2,PRTFDC1,STMN4,SCG2,FIP1L1,TMEM163,FAM47E,SLC17A6,PARP11,FZD3,UBE3B,PAK5,SMIM8,ACTR3B,RSPRY1,NETO2,NETO1,RNF146,SOCS4,SLC4A10" MicroRNA hsa-miR-4267:mirSVR_lowEffct hsa-miR-4267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-149 1.06E-145 4.36E-148 4.02E-147 414 1865 "DPF1,DGCR6,ABR,ASPHD1,ASIC2,ASIC1,NCKAP5,SLITRK1,ADCY6,GALNT13,ADD3,SLC12A5,ADORA2A,PWWP2A,KIAA1211,KCTD16,TBC1D14,DISP3,C1QTNF1,ABCD2,CARNS1,AMPD2,DPP10,ANK1,SEMA7A,CCDC146,FAM131A,PPFIA3,USP37,SHTN1,CDK10,PLA2G4C,LINC00173,PDE8B,MARK4,CAPRIN2,ASPH,CHRD,ATP1B3,ALDH7A1,DOCK11,ADAM23,CARMIL3,RGS9,KSR1,CDK5R1,ARHGEF7,NAE1,C5,LDLRAD4,CAMK2G,RUNX1T1,CBR1,CERS5,INA,CD86,CD38,DGKI,CDC27,CDH2,LRRFIP1,DLGAP1,CDR1,IGFN1,CHN2,CNOT8,TAOK2,NDST3,CLCN3,ABCG2,DNAJB5,TMEM155,MYRIP,ZNF521,ZFP28,CP,CREM,SH2B1,TRIM69,MROH8,LRIG1,MICAL2,ATRNL1,GALNT9,VAC14-AS1,PDE4DIP,RASGEF1C,DZIP3,CMTM5,PPP6R2,DCAF4,RUBCN,ECE2,NOS1AP,CYBB,HDAC9,GPRASP1,INTS1,DGKB,TOMM20,DAPK3,CTIF,SPATA2,DGCR5,CNIH3,FBXL5,RUSC2,COPS7A,KLHL3,GSDME,POM121,SV2A,NTM,GRIN3A,RAB39B,HS3ST2,CD99L2,DYNC1I1,DNM2,CPEB2,SLC25A18,ACOT8,DNAJB6,SEZ6L2,SEMA3D,SIDT2,PHF20L1,APH1A,MRO,GOLGA7,TENM1,CALCRL,HSD17B14,OLIG2,EPB41,EPB41L1,ANKRD13B,EPS8,NCALD,DNAJC27,RASL12,EXTL1,WAC,PTK2B,TUBB3,FCGR1A,TOMM40L,FCGRT,FDFT1,TESK2,FER,FGF1,CAMSAP1,SUCO,MEX3B,C1orf61,PCYOX1,SYNCRIP,RGPD5,SEMA4D,ATP13A4,NOP56,FLYWCH1,ZCCHC17,SPECC1,ATP2C1,NSG2,CELF1,GPR153,NSG1,TMEM151A,BRSK1,FYB1,JPH4,ARPP21,ZNF274,ERAP1,TMEM8B,DISC1,ATP8A2,WASF3,TUBA8,ARFIP1,SESN1,MALT1,GJB1,RND1,GLI2,GLYR1,RAB30,GLS,POLL,DCLK2,GNAS,GPD1,LILRA1,CCDC184,LPAR4,GPER1,RAPGEF1,GRIN2C,ZNF496,BTN2A1,FAM19A2,RNF165,GSTM5,ZBTB49,MFSD2A,TMEM179,WIF1,PACSIN2,MAN1B1,ATXN2L,LINC01102,MIER3,ZDHHC15,LRRC75A,SHISA6,CELF5,ATCAY,C2orf72,LRRCC1,TJAP1,SLC6A17,LRRTM3,ITGAM,SLC35G1,KCND1,CLVS2,KCNJ9,KCNK1,HECTD2,LOC100128239,MAN2A2,ZFYVE27,MAT2A,AQP11,MBD1,SYT9,CHIC1,MDM4,MEIS1,PPM1L,AFF1,JAKMIP3,MSRA,PTOV1,MX1,MYO7A,RTL5,ZNF862,FXYD6,ZC3H12B,NME4,CNOT4,DNHD1,NUCB2,OGG1,OPCML,OPHN1,LOC100128398,ZNF827,KCNK10,SNTG1,PDE1A,BEST3,PFKFB2,NLGN3,CAMKV,TMIE,JAKMIP1,CDIP1,ING3,PACSIN1,FA2H,NXPH1,POLR2F,TMEM235,PPP2R5E,PPP3CB,PROX1,PSD,LRRC49,PIGG,PTAFR,PLPPR1,UHRF1BP1,BDNF-AS,ZSCAN32,PTPRB,PPP2R3C,SLC25A48,ATG16L1,SLC25A41,ZCWPW1,TRIM68,RGS3,RGS4,RGS12,ARHGEF10L,RIT2,RIC8B,ARMC5,KIRREL1,ROBO2,ROM1,NEK11,TCP11L1,STK32B,ZNF331,SATB1,PRCD,TNFRSF19,CASC3,SH3BP2,KIF16B,ASAP3,ANKRD6,SLC1A6,SMTN,PKNOX2,LRRC55,SLC8A2,NAPB,SPHKAP,SMARCC2,CDK5RAP2,INTS9,SMARCE1,IFT122,INAVA,LIMCH1,MBD5,SNRPN,FAM219A,DOP1A,TNIK,DOK5,SP4,NMNAT2,TEX2,ERC1,SPTAN1,IQSEC2,RBM26,NFASC,TAB2,CLSTN2,POGZ,ZC4H2,LRRC4,RGL1,DIP2A,STAC2,KLHL7,NECAB1,FGD4,JMJD6,SUPT5H,SYNE2,SYT1,ANKRD28,KAZN,EXOC7,AGTPBP1,MGRN1,VWA3A,NAT16,USP32P1,FRYL,CYB561A3,ZNF106,FBXL16,ARL10,THRA,ENHO,TNS1,SMUG1,FNDC5,TTTY15,LINC00689,UGT8,FAM181B,BCL2L13,VLDLR,BEST1,WIPF1,LAT2,CLDND1,ZIC2,ZNF711,ATP6V0E2,GPR158-AS1,MKRN3,TMEM237,ZNF189,SPIRE1,MFF,GDPD5,LINC02210,STOX2,PRDM10,LMAN2L,MDH1B,GJC2,ACTR3B,FAM219B,JMJD1C,MSRB3,TTC7A,ZDHHC20,FRMD6,RNF146,SPATA13" MicroRNA hsa-miR-29b-1*:mirSVR_highEffct hsa-miR-29b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.17E-149 1.22E-145 5.02E-148 4.62E-147 396 1711 "ASPHD1,ACADM,NBAT1,TKTL1,KDM5D,DSCAML1,ADD3,PWWP2A,BEND6,DPY19L2P4,AP2A2,ZNF608,MTUS1,HECW2,TXNDC16,SMIM17,ABCD2,LTBP4,UNC79,FAM135A,ZNF687,ZFAT,OGT,LRCH2,LCORL,USP28,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,UPRT,GPAM,ALS2,API5,SHTN1,MIER1,SFMBT2,ARHGAP5,DACT3,ATP1B3,STX16,ATP2B3,RNF182,RGS11,RGS9,OSGIN2,CACNA1B,VXN,SYT6,CAST,RUNX1T1,CCNH,CDC27,CDH10,LGI1,MAGI1,DIS3L,SOCS6,MAP4K4,NIPBL,CNGA3,FAM149A,AKAP6,SLC25A27,BTF3L4,SLC4A7,RCHY1,COX4I1,CNRIP1,SLC35F1,CPS1,ANKRD44,GDA,SNCAIP,TENM4,FEZ2,SOCS5,CNTNAP2,UBXN2A,PHF14,CTH,NRSN1,PUM1,DCAF4,CCDC144A,CYBB,SNPH,ZFYVE16,IST1,DBI,AIF1L,ARMCX2,ZEB2,HP1BP3,BLOC1S6,AK5,HS3ST4,HS3ST2,NR1D2,DTNB,ABCC5,E2F5,EBF1,SEZ6L2,WDPCP,EDNRA,ATL1,TMTC1,FAM13A,PHF20L1,EGR3,AASS,GOLGA7,KCTD3,CALCRL,PAN3,COQ7,RCAN2,KCNMB2,SRRM1,DENND4A,NCALD,RTN3,TLR7,EZH1,F5,CEP78,FDFT1,GORAB,MED12L,UBE2E3,SEC23B,AGAP3,RGPD5,SLC37A3,NELFCD,NBEA,APOPT1,UFM1,TBR1,OGA,GABBR1,GABRA2,TRAF3IP2,CAB39,ZNF274,NEK6,ERAP1,DISC1,KIAA1841,CPLX1,TUBGCP4,SULT1C4,AHDC1,ADAM28,USP19,MALT1,RUNDC3A,COPS8,SPIN1,TNRC6A,DCLK2,GNAS,GPD2,ATF7,EML4,TMEM121B,CECR2,GRIA2,GRIA4,PLCD4,NR3C1,ZBTB49,FICD,RASSF8,HAS2,TOX2,ELOVL5,HMGCR,NEGR1,HSP90AA1,HTR5A,NKD1,LRRTM3,OLFM3,KCNC1,KCNC2,KCNK1,KCNK3,KCNMA1,KCNN3,KIF2A,HECTD2,NCOA7,MARK1,MAT2A,MBD1,SYT9,TM6SF1,MEST,KITLG,MITF,MKLN1,XRRA1,MOBP,ZNF680,MRPL42,ADAM22,SCG3,NCF2,NEFM,NEFH,CCDC13,NEUROD1,NF1,CNOT4,NPR2,SLC11A2,NTRK2,GPR88,SNTG1,PCSK2,PRTG,ENPP2,PDYN,SLC10A4,OLA1,ZNF655,KCTD15,ST8SIA5,PLCL1,PLP1,HMGCLL1,STRN3,EXOSC10,PMS2,PRRX1,EPB41L4B,FA2H,POU6F1,MINDY2,TATDN3,PPP3CA,PKIA,MAPK9,MAPK10,GRAMD1C,VPS13C,SIDT1,SNRK,QRICH1,MTMR10,TMEM260,PTPN13,OCIAD1,TTC13,PID1,TMEM255A,CCDC40,RAD52,ZNF493,RASGRF1,RASGRF2,FEZF2,ZYG11B,RET,GTDC1,FIGN,RFX2,RNF220,SLC25A36,RIC8B,PBRM1,ZNF532,SETD5,C12orf49,CARF,ROBO1,ROBO2,ROM1,ELP2,RPE,RPE65,FBXW7,KIAA0895L,ATP8B4,GLDN,ADAL,LRRK2,CNTNAP3,LGR4,MEG3,ABCA11P,SOX8,KCNIP3,CCDC112,LRFN5,SCN3A,LINC00461,FNIP1,TNFRSF19,ITSN1,CPEB3,SHC4,HKDC1,CHD9,PAAF1,SLA,SEPHS1,SHANK2,SLC15A2,SCMH1,SPHKAP,MBD5,CABCOCO1,SNRPN,UNC80,SCN3B,SP2,SP4,PEG10,TAB2,STOX1,SMOC1,EPB41L3,NXT2,ZSCAN29,NEK4,SEPT8,DIP2A,KANK1,AJAP1,NSFL1C,VPS13A,FNDC9,SYT1,ANKRD28,ANKRD12,MTCL1,UNC5D,WWC1,IQCE,EHBP1,SATB2,TCF7,TCF7L2,TCF12,TMEM151B,PCDHB3,GPRIN3,FRYL,AHCYL2,DICER1,SIRT1,SPX,ITGB3BP,AKTIP,HEY1,BHLHB9,KAT6B,NPL,TPM3,ZNF384,PRMT8,TTTY15,RFTN2,CADM1,UCHL1,GORASP1,PITPNB,FAM181B,PLEKHH2,TBC1D15,RBFOX3,WIPF1,FMN2,ZNF138,ZBTB16,REEP1,SPIRE1,WNK1,EMSY,PRTFDC1,RNF103,ADAMTS9,SCG2,SIGLEC10,NAV3,PLSCR4,PDSS2,PAK5,KAT6A,PHTF2,ADAMTSL3,NETO1,CBLN2,JPH3" MicroRNA hsa-miR-204:mirSVR_highEffct hsa-miR-204:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.61E-149 1.46E-145 6.00E-148 5.53E-147 383 1603 "DPF1,TTYH1,SDE2,KCNH8,TKTL1,CSMD2,ARID1A,XKR4,NDRG3,KLHL32,SLITRK1,CCDC85A,GALNT13,ADD2,ADD3,CDC7,ADORA2A,PWWP2A,ESYT2,SLC44A5,AP2A2,INTS2,MTUS1,TAOK1,ADGRF5,C1QTNF3,SEMA6A,SPOP,ALCAM,BIN1,ZFAT,USP28,UPRT,ALS2,SEMA4G,TMEM263,SPTBN4,RGS20,MARCH3,STK33,DDX3Y,ATM,ATP2B1,TTLL9,SEC11C,RGS9,FGF17,PROM1,NAE1,C5,OSGIN2,CACNA1E,CACNB2,KALRN,CAMK2D,TRIM41,SYT6,CCNH,MTMR7,CDC42,CDH2,LGI1,L3MBTL4,SOCS6,CHN2,CASC2,MS4A7,PLAA,CLCN3,CLU,CLTC,NIPBL,FHL5,ARMC8,AKAP6,COL4A5,SLC25A27,AHCTF1,ZNF521,RBM39,HAPLN1,RNF14,GDA,TRIM69,FEZ1,SUSD5,VAC14-AS1,DZIP3,ERC2,CFAP61,NRSN1,RIMS2,RUBCN,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,TOX,CENPL,LONRF1,DGKG,TMEM170A,DAPK1,DBI,SIRPA,ARMCX4,ARMCX2,DGCR5,ZEB2,TIAM2,FBXL5,DDX46,RHOBTB1,PLPPR4,SPOCK3,G3BP2,RABGAP1L,FAM107B,ZNF582-AS1,CHRDL1,GRIN3A,DMD,HS3ST2,DNM2,DMTF1,SLC12A6,PDCD6IP,RCAN1,DTNA,FRY,EFNB3,CELSR3,APH1A,EGFR,KMT5B,EGR3,RASA4,ELAVL3,C8orf37,EPHB1,RABEPK,SRRM1,SIRPB1,WAC,RPS6KC1,ACSL4,SCML2,STRADA,FER,KIAA1109,FGFR1,POLK,SUCO,CAP2,ATP13A4,SGIP1,SLC37A3,NBEA,SMC2,USP16,RASL10A,ATP6V1H,ZNF605,KHDRBS3,NSG2,NSG1,STAU2,B3GAT1,AP4B1,STAG2,GABRA2,GABRG1,GABRG2,HBS1L,AHCYL1,BRPF3,ARPP21,ZNF274,NEK6,ERAP1,C15orf41,LRRC37A6P,GCNT2,GDF9,PCDH17,GGT7,PPARGC1A,GLRB,TOX3,ZNF638,RAB40B,GPT2,GPD2,FUT10,RAPGEF4,GRIA2,GRIA4,NR3C1,MAP4K5,IRAK3,RASSF8,HAS2,HMGB1,GABARAPL2,HMX1,OPALIN,SMAP1,IRF8,LRRCC1,SCRT2,INSM1,JAK2,OLFM3,KCNC2,KCND2,KCNK2,STXBP5,SYTL4,HECTD2,NCOA7,MAG,LOC100128239,ZFYVE27,MBNL1,MEIS1,MGAT3,MMP16,CD200,ERICH3,MRPL42,NF1,NOVA1,LRIT2,NTRK2,OPHN1,SNTG1,PCDH9,PDE4A,PDE4B,PDE4D,BEST3,CDK14,PIK3R1,FAM218A,RETREG1,XRN1,GPSM2,SMIM7,LRP12,PRRX1,SEPT4,SLC36A4,POLR2F,POU3F2,MAPK9,VPS13C,GDPD2,SNRK,PIGG,SPDL1,PTPRB,OCIAD1,PTPRD,EML5,PTPRE,C1orf109,PTX3,PID1,CEP97,TMEM255A,USP47,CCDC40,ZNF793,HKR1,ZDHHC14,GTDC1,SEC61A2,ZFHX4,CARF,GSTCD,CCDC25,UEVLD,FBXW7,TCP11L1,KCNIP3,RXRG,TMEM156,AMER2,MIR124-2HG,ATXN2,SCN2A,LRRTM4,FNIP1,ELMOD1,SELL,ASRGL1,ARX,FERMT1,KIF16B,SHC4,FHOD3,CTXN2,KANSL3,YPEL4,SLC8A3,BTBD7,SORCS3,MYH15,SMARCE1,RCOR3,SNRPN,UNC80,MYT1L,TRERF1,ZCCHC24,MYCBP2,KDM4C,ZNF423,ZC3H13,RBM26,SRPK2,ATP10B,SMOC1,ZC4H2,SS18,ERBIN,ZSCAN29,ELOVL4,RGL1,GANAB,FNDC9,SYPL1,TACC1,ANKRD12,PJA1,CAMTA1,DNMBP,TCF4,SATB2,ZEB1,TCF12,SYNE1,FRYL,TEX15,SIRT1,GPR161,THBS4,GZF1,TIE1,ZFP91,ERCC6L2,TMPO,NPL,TPM3,TRPC1,ZMYND8,ANO5,RPL7L1,AMOT,FLRT2,PLEKHH2,VSNL1,ZNF781,GUSBP1,XRCC4,MICU3,TMEM237,EMSY,PRDM2,STOX2,PRDM8,VPS35L,GAL3ST3,SLC17A7,PLSCR4,RGS7BP,DOCK8,ST7,FBXO36,RNF170,JPH3" MicroRNA hsa-miR-505*:mirSVR_lowEffct hsa-miR-505*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.14E-149 2.89E-145 1.18E-147 1.09E-146 396 1715 "VWA5B2,SERPINA3,ASPHD1,SYN3,EMILIN3,METAP1D,GPRIN1,GALNT16,SLITRK1,GALNT13,ADD1,SORCS1,GRAMD1B,USP31,ADORA2A,KIDINS220,AP1B1,CASKIN1,AK2,C1QTNF1,LRRC7,CARNS1,MARCH4,PCDH10,ALK,SYT13,MRTFA,AMPD2,ANK3,LCORL,CNTNAP1,APAF1,APBA2,EPB41L5,APLP1,GPAM,FAM131A,PHYHD1,PPFIA3,SEMA4G,TMEFF1,ARNTL,ARRB1,ZSCAN18,NUMB,ASTN1,CCAR2,DPY19L3,RIPK1,NRP2,CFLAR,KSR1,SYNJ1,SYNJ2,NAE1,LINC00906,CACNA1G,BTRC,KALRN,PTBP2,CAMK2A,CAMK2B,TRIM41,VSTM2A,RUNX1T1,ENTPD6,LOC730101,IGFN1,ADGRG1,ASIC3,CHM,CASC2,SYNPR,CHRNB2,NRXN3,COG1,NGEF,FAM189A2,MAP4K4,NIPBL,IGLON5,CNTN1,AKAP7,PCYT1B,ARMC8,WHRN,ABI3BP,SMARCAL1,SEC31B,CREB5,C1QL2,CS,CSF1R,RGS6,ATRNL1,DZIP3,PITPNM3,CMTM5,CTNND1,NRSN1,ZSCAN23,DCAF4,MYADM,RIPOR2,TOX,PHF19,TBC1D5,CTIF,SIRPA,DBN1,ARMCX4,DCC,PITPNC1,SPATA2,DNAJC6,ELMO1,COPS7A,KIAA0319,MED24,DDX46,RHOBTB1,SV2B,DLG2,DNM1,HS3ST2,MED12,SLC12A6,ATN1,DNAJB6,EDN1,FAM135B,ANKRD46,CNNM1,RASGRP1,SIDT2,YAF2,SORBS3,EIF5,SRPK3,EPHB1,SRRM1,SPEG,VPS26C,DNAJC27,RCSD1,SIRPB1,KATNAL1,F3,F5,WAC,TMEM132C,CHST15,FCGR3A,STRADA,FDFT1,GTF2IRD2,FGF1,POLR1B,BAIAP2,AMOTL2,SYNCRIP,FLT1,FLYWCH1,NBEA,HVCN1,ERGIC3,STAU2,DOT1L,STAG2,MEGF11,MEGF10,GABBR1,GABRA1,CHL1,ZNF234,ZNF274,GHDC,GAP43,SRRM4,GATM,ALDH1L1,TUBGCP4,GGTA1P,PPARGC1A,RUNDC3A,TTBK1,SPIN1,RAB30,DCLK2,GNG4,ADGRA3,ATF7,PRLHR,GPR17,GPR34,SPACA9,ADAMTS13,PRDM5,GRM5,LINC01089,LINC00839,KAT7,MFSD2A,LINC01551,RNFT2,ATOH8,CELF3,UBE2QL1,PADI2,HMGCL,ZDHHC15,FAM95B1,KIAA1755,TJAP1,SCIN,LIX1,ITGA7,SLC35G1,KCNA6,KCNJ11,KHK,KIF5A,KIT,KLRC3,LAMP2,STMN1,LSS,C2orf80,MAG,CLEC18A,LOC100128239,MAN2A2,MAP6,MBNL1,MDM4,MIA2,KITLG,SCAMP5,MID1,PPM1L,MOBP,MOG,CD200,N6AMT1,TAGLN3,C10orf105,HNRNPM,NAP1L1,NCAM1,NEK1,NHLH1,CNOT4,SLC11A2,OGG1,OXTR,ZDHHC22,PDE1B,PDPK1,GPR173,TMIE,CCSER2,XRN1,SLC25A23,TATDN3,PPP2R5E,PPP5C,PKN2,MAPK4,MAPK8,MAPK10,DIRAS2,SLC22A23,CYBC1,LRRC49,WDR25,ANKHD1,ELOVL2,STK32A,PTPRO,RIPOR1,RAD52,RALGDS,SH3TC2,ATG16L1,NWD1,RASGRF1,RASGRF2,ZDHHC14,TRIM68,PRRT2,RFX5,RGS3,RGS12,MRPS18A,SEC61A2,ALG9,ROBO1,RPL15,UEVLD,KIAA0895L,ATP8B4,PAQR6,RTKN,AP1AR,FOXRED2,ATXN7,PRCD,SOX6,FOXRED1,ITSN1,PAAF1,FAM81A,SLC2A5,LRRC55,SLC8A3,SLC12A4,SPHKAP,SLC22A4,SMARCD3,RIMS1,TMCC1,MYO16,PDZD2,WDTC1,SOX10,ZSWIM8,IDI2-AS1,SPTAN1,IQSEC2,MCF2L2,NFASC,C11orf87,CAMTA2,ZC4H2,NCDN,MAPK8IP3,STAU1,SEPT8,CEP68,DIP2A,STAC2,STX1A,SEPT3,NSFL1C,COBL,KAZN,MTCL1,TAL1,ALG1,IQCE,ATMIN,RPGRIP1L,SYNE1,AHCYL2,HIF3A,RNF216P1,TF,FAM200B,SIRT1,DICER1-AS1,ITGB3BP,THRA,TMEM9,TLL2,ANKRD24,PRRT1,TNS1,CDK20,ZNF384,ZNF346,SMUG1,ZMYND8,TUB,TUBB1,AMOT,PLEKHH2,BCL2L13,VSNL1,RBFOX3,KLC2,SLC13A3,ATP6V0E2,PLPP4,SLC26A10,CRB2,SH3GLB2,ZNF213,MFF,PRDM2,PRTFDC1,RGS7BP,UBE3B,ZNF248,SSPN,PIANP,ST8SIA2" MicroRNA hsa-miR-300:mirSVR_highEffct hsa-miR-300:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.04E-149 3.95E-145 1.61E-147 1.48E-146 371 1509 "ACADM,ACLY,CSMD3,CCDC85A,ADORA3,ADRA1B,NLGN4X,GPR158,KCTD16,ABCD2,PCDH10,FAM135A,LRFN1,ANK3,PPFIA1,APAF1,DGKD,SHTN1,ARNTL,ASPH,ZBTB10,NUMB,EIF4G3,STX16,ATP2A2,ATP2B1,DOCK11,CARMIL3,BACH1,DST,NAE1,RAB29,IL33,CACNB2,THSD7A,KALRN,SPAG9,ZNF501,LDB2,AIFM1,CDH10,MAGI1,CFL2,SYNPR,B4GALT6,KMT2C,RAB33A,RAB28,NRXN1,NGEF,ABCG2,HECTD1,CNR1,ARMC8,BTF3L4,AHCTF1,ACBD5,ZNF521,TRIM69,FEZ2,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,CST3,PLXNA4,BOC,DOCK4,HDAC9,ARHGAP24,FRMPD4,TOMM20,GIT2,ARMCX2,YTHDC1,C8orf34,BLOC1S6,ZC3H11A,G3BP2,RABGAP1L,FAM107B,CHRDL1,RAB39B,DNM2,DMTF1,DPP6,DRD1,DYRK1A,E2F5,EBF1,SNX29,ANKRD46,CNNM1,KLHL5,FSD1L,PHF20L1,MBNL2,KMT5B,KCTD3,EIF4G2,TENM1,EML1,PAN3,EIF1,VPS13B,EPB41,EPB41L1,EPB41L2,LRRC17,EPHA5,EPHB1,KCNMB2,EPS8,DENND4A,CEP85L,RRAGB,DLC1,CEP78,TESK2,ZNF589,FGF1,POLR1B,BAIAP2,ATP5PD,FOXG1,FOXF2,PCYOX1,SYNCRIP,FOXO3,NBEA,SORBS1,SMC2,ATP6V1H,PRELID3A,STAU2,MSANTD4,PHYHIPL,GABRA2,GABRB3,GAD1,ZMYND11,GALC,RAPGEF6,ARPP21,GALR1,NEK6,NCKAP1,MTHFD2,C15orf41,KIAA1841,AHDC1,RUNDC3A,GLRB,TNRC6A,PCDH11X,MAP7D2,KCNMB4,ADGRA3,TDRKH,LILRA1,GPR34,CECR2,PCLO,GRIA1,GRIA2,RFFL,NR3C1,GRM3,GRM5,GRM8,AP4S1,PSIP1,ADAMTS6,FAM222A,IRAK3,MIER3,HMGB1,TCEAL6,ZNF546,IGFBP1,ZIC5,RBPJ,ZNF678,RIPPLY2,ITGAV,JAK2,KCNA4,KCND2,KCNJ3,KIT,STXBP5,VWA5A,HECTD2,MAP4,MARK1,MATN2,MBNL1,SYT9,LRP1B,MEIS2,SRSF12,MITF,ERICH3,ZNF680,MSR1,MYO9A,NEXMIF,NAP1L1,NAP1L2,NAP1L3,P2RY13,NEUROD1,NF1,CNOT4,HCN1,OPHN1,CNTN3,PBX1,PCDH8,PCSK2,PDE1C,ENPP2,PENK,ZNF655,FAM218A,CCSER2,XRN1,KCTD15,NLE1,PLCL1,HMGCLL1,PURG,PMP22,ING3,FA2H,KANSL1,RANBP3L,PRKACB,CEP41,MAPK4,GDPD1,SNRK,PTCH1,ANKHD1,TMEM260,OCIAD1,PEX2,TMEM231,RAP1GDS1,OXR1,MSANTD2,SLC6A15,REV3L,GTDC1,SLC25A36,RIC8B,RPRD1A,ZNF532,GSTCD,ROBO2,TMEM206,RPS20,ABCA11P,WLS,SALL1,SEMA6D,SATB1,SCN7A,FNIP1,TNFRSF19,ELMOD1,CASC3,SFPQ,SCAF8,KIF21A,SH3GL3,PPM1E,CHD9,R3HDM2,CNKSR2,SYBU,PAAF1,WDR37,PPP4R3A,EPN2,RUFY2,SLC6A8,ATF7IP,GKAP1,INAVA,MBD5,KIF13A,UNC80,TRERF1,SP4,SPTB,KIF1B,IQSEC2,RBM26,DDN,LMO3,CLSTN2,SAMSN1,SSTR2,EPB41L3,ZC4H2,LRRC4,NXT2,SEPT8,GANAB,SYT11,VAMP1,ARHGEF9,POPDC3,ANO4,TBX15,EHBP1,ZEB1,SYNE1,PCDHB4,FRYL,HIF3A,TEX15,TEK,DICER1,ZFPM2,ZMAT3,HHIP,NACC2,HEY1,ACTR6,ASXL3,NR2E1,BEX4,R3HDM1,KAT6B,TP53BP1,TP53BP2,TRIO,TRO,SSBP2,ZKSCAN5,SGK3,UBE3A,USP1,ZNF709,BEST1,TBC1D15,VSNL1,PCDH20,ZBTB14,MICU3,FMN2,LYPD6,ANKS1B,UPF3A,EMSY,LRP8,MDH1B,PCDH15,NAV3,SNX27,SLC17A6,DNAH10,FAM13C,AMN1,PHTF2,ZNF248,NETO1,CPNE4,JPH3" MicroRNA hsa-miR-145:mirSVR_lowEffct hsa-miR-145:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.22E-149 4.62E-145 1.87E-147 1.72E-146 415 1881 "DPF1,TTYH1,SERPINA3,ABR,ASPHD1,PLEKHH1,FZD9,USP31,FAHD2CP,BEND6,AP2A2,TBC1D14,AK2,ALAD,PCDH10,KIF6,OGT,LRCH2,ANK3,CCDC146,MAP4K3,PPFIA1,PPFIA3,CDC14B,IGDCC4,ZFYVE28,ARHGAP5,ARRB1,RGS20,RASL11B,INSYN2B,SLC4A4,ATP1B3,RNF182,DPY19L3,ADAM23,ST3GAL5,BSN,MYRF,KALRN,TRIM41,VXN,MAP7,RUNX1T1,NFS1,CBS,CLDN10,AIFM1,SCARB1,NEURL1,CDC27,ZBED1,CDH8,LRRFIP1,LGI1,DLGAP1,CCPG1,CLGN,CACNA2D2,SOCS6,CHM,CHN2,NDST3,RAB33A,CLTC,NGEF,FBXO7,ABCG2,QKI,SULT4A1,HECTD1,MAP4K4,CNR1,AKAP7,CABP1,LETMD1,ACBD5,ZNF521,CNRIP1,CP,CREB5,AKAP12,RNF14,CLIP3,CS,RASGEF1C,DZIP3,CTNND1,RUBCN,CYBB,DOCK4,GAPVD1,KIAA0513,ZNF337,TM9SF4,DAPK1,DBI,GIT2,DNAL1,ZNF804A,ELMO1,KIAA0319,SACS,SGSM2,MTX3,ARNT2,DNAH9,DPP6,DPYSL2,ATN1,DSCAM,DTNB,GOLT1B,TSPAN5,CNNM1,FSD1L,EFNB3,FAM13A,GPR61,SUGP2,APH1A,AASS,ASB3,EIF5,TENM1,CALCRL,LRRC23,EPHA5,SRRM1,EPS8,ERBB4,CDKL3,CLVS1,ABCA8,PTK2B,CORO2B,ATP8A1,RACK1,FCGR1A,FCGR1B,FCGR3A,FER,FGF11,FGF13,AMOTL2,SUCO,ANKFY1,PSD2,EFCAB2,SORBS1,POMT1,SMC2,APOPT1,PDLIM5,ZNF605,NSG1,STAU2,KBTBD12,ABLIM2,MEGF11,GABRA2,GABRG2,CAB39,ERAP1,GFAP,ZNF276,DBF4,GLS,ZNF638,FUT10,NUDT21,EML4,CNTRL,STMN2,GRIA2,C1QL4,GRM1,GRM2,PRDM5,GRM7,KIF3A,LINC00839,ZBTB45,LINGO1,SLC2A6,TMEM179,RASSF8,HPS5,FRMD5,BACH2,HMGCR,NEGR1,HSF2,LRRC75A,CELF5,SMAP1,EID2B,IRF8,IDH3A,ZIC5,KNDC1,ZNF385B,ITGAV,KCNA6,KCNC2,GPR62,KCNJ3,KCNN2,KIF2A,KIF5C,PAXBP1,SYTL4,FGFBP3,ARHGAP12,GPR155,MAP6,MBNL1,MBP,SYT9,TM6SF1,XRRA1,CPNE9,CCDC80,BLOC1S2,MTR,MYCN,MYO5A,MYO6,MYO7A,NEXMIF,NCAM2,NEUROD1,NFE2L2,ALDH1L2,SLC11A2,NTRK2,NUCB2,NUMA1,OGG1,LOC100128398,KCNK10,PAK3,PBX1,PRTG,PDE4B,ENPP2,PFKFB3,CDK14,ZDHHC8,SERPINI1,KCTD15,EPN1,PRIMPOL,PMP22,NXPH1,PRKACB,PKIA,PRKCB,PRKCZ,EPDR1,GRAMD1C,PIGG,CNTLN,MTMR10,PTK2,PTPRE,PEX2,NKAIN1,TUG1,TMEM231,PPP2R3C,RAB5B,CEP97,NWD1,RASGRF1,KHDRBS2,ZDHHC14,RDX,SLC6A15,ZMAT4,RFX2,RFX3,RFX5,RGS3,KIF7,RIC8B,DCUN1D2,CARF,ROBO2,CCDC25,GLDN,ACER3,RPS6KA2,STK32B,MAP6D1,MEG3,HUNK,ZNF568,TMEM156,SEMA6D,LRFN5,SCN3A,GALNT10,ASRGL1,ITSN1,PPP1R9A,SH3GL3,CPEB3,HKDC1,AMBRA1,FBXO11,ANKRD6,DHX30,FAM214B,KANSL3,CCDC88A,SLC12A2,NAPB,BTBD7,SLC20A2,SLC22A4,SLIT1,SORCS3,SMARCD3,SMARCE1,RCOR3,SNRPN,SCN3B,SOX1,SOX11,DOK5,NMNAT2,CLUAP1,HECW1,UHRF1BP1L,KIF1B,MCF2L2,RBM26,ATP10B,ITPRID2,SST,SEPT8,CEP68,GANAB,NECAB1,MLC1,FGD4,JMJD6,SUPT5H,SYNE2,ARHGEF9,C3orf70,COBL,ANKRD12,TBCEL,MGRN1,TBX15,TCF4,SIN3B,ZFP90,TPCN2,TRIM2,NAT16,FAM189A1,NSD1,ARHGEF12,CRTC1,FRYL,TEX15,SIRT1,DICER1-AS1,ZFPM2,CRB1,SPX,TLL2,ERCC6L2,TMOD1,TMPO,DAAM2,TPD52,WBP2,ZNF346,AMACR,STXBP4,TRPM2,ZMYND8,TST,PRR18,TUBB1,FLRT1,ZIC2,ZNF28,TCEAL7,REEP1,EML6,ZFAND5,SMARCAD1,MEIS3,DNALI1,SLC38A1,CSDE1,EVI5,LINC02210,SCG2,PCDH15,CAB39L,WNK2,SLC17A6,PLSCR4,DNAH10,DOCK8,PHTF2,JMJD1C,KLHDC1,SOCS4" MicroRNA hsa-miR-323b-3p:mirSVR_lowEffct hsa-miR-323b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.90E-149 5.00E-145 2.02E-147 1.86E-146 371 1510 "CPNE2,RALGAPA1,TTYH1,SYN3,NCKAP5,CSMD3,SLITRK1,TMCC3,ADD3,ERMN,PTCHD1,ADRA1D,INTS2,PCDH19,CC2D2A,AK2,SMIM17,SYT13,AMPD2,DPP10,ANK3,EP400,ANXA7,MAGEE2,ALS2,SHTN1,AQP4,TMEM263,ZFYVE28,PDE8B,STK33,ASPH,CHRD,CCAR2,ATP6V1G2,ADAM23,CDK5R1,ST3GAL5,CACNA1D,CACNB2,CALM1,PTBP2,SLC25A14,CAST,ISPD,ARHGEF25,CBR1,SLC16A4,CD38,LRBA,SEPT7,CDC27,CDC42,CDH2,ZMYM4,ZNF445,CDO1,DLGAP1,TIGD7,CCPG1,CLGN,SYNPR,C7orf61,RAB28,MAP4K4,CNN3,AKAP7,LETMD1,ZNF521,HS3ST5,SEC31B,TRIM69,CS,SNCAIP,SEC24C,CSF3R,ARHGEF10,CSNK1E,SOCS5,SLITRK5,APPL1,NRSN1,NOS1AP,KIAA0408,TMEM170A,SPOCK2,DBI,PITPNC1,ZEB2,RUSC2,TMEM130,ZC3H11A,DDX46,PLPPR4,SNAP91,SACS,WDR20,EXOG,DNM1,NR1D2,CASP8AP2,DRD1,ABI1,AASDH,EBF1,EDN1,HIPK3,GPR61,PHF20L1,SUGP2,EGFR,KMT5B,ABI2,EPHA5,RABEPK,SH3YL1,DLC1,FCGRT,MED12L,KIAA1109,FGF1,FGF14,PRKAG2,FLT1,FOLH1,JKAMP,TACC2,SORBS1,UFM1,NSG1,STAU2,PHYHIPL,GABRA2,GALNT15,GABRG1,AHCYL1,ARPP21,ZNF274,ERAP1,MTHFD2,ATP8A2,IGSF5,SULT1C4,WASHC2A,ADAM28,MMADHC,DBF4,TNRC6A,GLUL,HTATSF1,MAP7D2,DCLK2,RAPGEF4,GRIA2,GRIA4,GRIK2,GRM8,KIF3A,PSIP1,MAP4K5,ATOH8,CELF3,NXPH3,ARHGAP19,HLF,GABARAPL2,AGFG1,ICA1,IDH3A,IFI16,RBPJ,DOCK7,IL6ST,IL12A,KCNK2,LIG4,HECTD2,ARHGAP12,IL17D,MEIS1,MEST,KITLG,CD200,ERICH3,MSI1,BCO1,NRBP2,CTNNA3,MXI1,NAP1L3,NCAM1,NCAM2,NEFM,NEUROD1,NF1,SLCO1C1,ALDH1L2,DNHD1,NTRK3,CLDN11,PDE3B,PDE4B,PDE4D,PFKFB2,ABCB1,SERPINE2,KCTD15,NLE1,FAM216A,ST8SIA5,PLCL1,HMGCLL1,PURG,TRHDE,STRN3,LRP12,EPB41L4B,NXPH1,POU3F2,PPM1B,CCDC144B,PPP2R5C,KANSL1,PKIA,RAB39A,MAPK4,HYDIN,GDPD1,RELN,VPS13C,SLC22A23,WBP1L,QRICH1,CNTLN,PTCH1,PLPPR1,UHRF1BP1,BDNF-AS,PTPN13,PTPRD,EML5,C1orf109,PTPRZ1,ZNF615,QDPR,CCDC40,ZNF793,FAM184A,NWD1,OXR1,KHDRBS2,MSANTD2,RDX,FIGN,RFX3,RFX4,RGS12,KCTD17,SEC61A2,SLC25A36,RNASEL,ZFHX4,C12orf49,ROBO1,ROBO2,ELP2,CCDC102B,BAALC,CNTNAP3,RMI1,SMPD3,SFPQ,TRA2B,HSPA4L,SGK1,PPM1E,KIF16B,CNKSR2,SYBU,ZNF365,SLC1A6,SLC6A11,CCDC88A,SLC9A5,TRIM67,ELMO2,TTC17,ANKRD36,RIMS1,MBD5,TMCC1,MYO16,UNC80,RBM34,MYT1L,FNBP1,DOK5,MYCBP2,MCF2L2,LMO3,LARP4,NXT2,GSE1,SYNE2,VAMP1,COBL,ANKRD28,TAC1,KAZN,CAMSAP2,TMEM136,TCF7,ZEB1,TRIM2,SYNE1,RALYL,PCDHB6,SIK3,TEK,ZFPM2,ZMAT3,HHIP,TJP1,DDHD1,KAT6B,TPM1,C9orf85,RGMB,TSC1,TMEFF2,FAM155A,UGT8,SLAIN1,PITPNB,BCL2L13,MGAT5B,CCDC14,WIPF1,NSD2,RICTOR,SLC13A3,XRCC4,ZBTB14,ZIC2,ZIC3,ZNF28,ZNF540,CELF4,ZBTB38,SPIRE1,PRDM2,LRP8,EVI5,STOX2,HPS4,NAV3,FAM47E,MVB12B,PDSS2,RGS7BP,FZD3,RTN4,CERS6,ACTR3B,ZNF248,SNX14,KLHDC1,DPF3,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-1271:mirSVR_lowEffct hsa-miR-1271:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-148 6.03E-145 2.42E-147 2.23E-146 382 1601 "DGCR6,NBAT1,KDM5D,SLC25A25,PWWP2A,MTA3,SLC44A5,KCTD16,ADGRF5,SEMA6A,CEP126,PCDH10,GPRASP2,AMPD2,ZFAT,OGT,ANK3,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APBB2,APC,ARNTL,RGS20,LINC00173,NUMB,ATP1A2,ATP1B3,B3GALT2,BACH1,MTMR3,CACNA1G,NIPA1,MYRF,CDK5R2,MMD2,CALB1,CERS5,INA,P2RX6,SCARB1,EVI5L,L3MBTL4,SRSF11,RAB3C,LSMEM2,NRXN3,NRXN1,CLTC,MAP4K4,CNR1,BAG4,CLOCK,ENTPD4,ANKRD44,MICAL2,SUSD5,ATRNL1,CNTNAP2,GREB1,NRSN1,RIMS2,USP6NL,CCDC144A,CYBB,DOCK4,TOX,ZFYVE16,PHYHIP,IST1,TMEM170A,SCRN1,SPOCK2,PLEKHM1,ELMO1,TIAM2,CEP170,RHOBTB1,SACS,HS3ST4,USP3,DYNC1I1,CPEB2,SLC12A6,PDCD6IP,RCAN1,ARRDC4,DTNA,TOM1,MAMLD1,ABCC5,AASDH,EBF1,SNX29,EDNRB,TMTC1,MBNL2,KMT5B,ABI2,EGR3,KCTD3,EIF5,ING4,RGS17,DCTN4,OLIG2,EPB41L2,EPS8,IGSF6,NRN1,ARMCX1,CACNG3,RACK1,CEP78,PRMT5,FER,FGF13,FGR,AMOTL2,SUCO,FLYWCH1,CAMKK2,ATP2C1,KHDRBS3,CELF1,CGREF1,SARAF,FYB1,HRASLS5,CHL1,ZNF234,LRRC37A6P,CYP46A1,SESN1,FREM1,PCDH17,TXNL4A,CRCP,TOX3,TNRC6A,AIFM3,STARD3,KDM2B,LUZP2,RAB40B,GPD2,PRUNE2,ATF7,PRLHR,LPAR4,GPR34,CNTRL,GRM1,GRM2,GRM5,ZNF496,GSTM5,MFSD2A,GUCY1B1,ARHGAP19,KLF12,HMGB1,ICA1,FAM95B1,LINC00667,LRRC25,RBPJ,DIPK1A,SLC35G1,KCNB1,KCND2,KCNK2,KCNMA1,KCNN3,KIF2A,KIF5C,STXBP5,LAMP2,LIMS1,HECTD2,SMAD1,LYPLAL1,SYT9,CHIC1,MDM4,SRSF12,MIA2,MID1,COMMD5,MT1M,MT3,N6AMT1,MTR,RSPO2,NEXMIF,NAP1L3,NCAM1,NCAM2,NELL1,NEK1,NEUROD1,NPTX2,SLC11A2,NRCAM,CHAMP1,OGDH,OLR1,LOC100128398,ZDHHC22,PAH,PCDH8,PCDH9,PCMT1,CDK18,PRTG,PDGFRA,GPR85,PIK3R1,CCSER2,ZFYVE21,RETREG1,HMGCLL1,EXOSC10,SCHIP1,MAGEL2,ING3,TMEM235,PPP3CA,VSTM2L,PRKAB2,MAPK9,GRAMD1C,MASP1,PIGG,BDNF-AS,PTHLH,PTK2,PTN,PTPRG,PTPRZ1,TMEM145,PPP2R3C,SLC25A48,RAD17,RALGDS,ATG16L1,ZNF493,OXR1,ARID4A,RET,ERI2,GTDC1,RFX4,PRIMA1,ARHGEF10L,RNF220,SLC25A36,CCDC82,TMLHE,ALG9,ROBO2,ELP2,FBXW7,SPIN3,PTGR2,ABCA11P,STX1B,RYR3,AMER2,SATB1,ATXN1,LRRTM4,SCN7A,SELL,SCAF8,NTNG1,SHC4,FNDC3A,SLITRK3,ZNF365,SLC1A3,SLC8A3,ARHGEF40,CCDC88A,SLC12A2,SLC14A1,MTERF2,ELMO2,ATF7IP,CPEB4,SORCS3,CDK5RAP2,LIMCH1,KIF13A,FAIM2,PALLD,TMCC1,SOX2,FNBP1,GLT8D1,PEG10,SPTB,MCF2L2,NPAS3,CLASP2,TROVE2,STOX1,SSPO,SEPT8,DIP2A,SYNE2,COBL,TACC1,CAMTA1,ADGRL3,ANO4,SATB2,TRIM2,TCF12,PCDHGB7,SYNE1,DOCK9,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,TMPO,KCTD2,TNR,TPD52,TPM2,SYNPO2,PRMT8,CLHC1,SGK3,CADM1,PLPPR2,P2RY12,RICTOR,XPO1,XRCC4,ZBTB14,ZIC2,ZNF23,FMN2,LYPD6,TCEAL7,EML6,ZNF189,PLPPR5,UPF3A,PMEPA1,CADM2,PRDM2,PRDM8,PRDM10,VPS35L,TMEM163,SLC17A6,MVB12B,C12orf4,ST7,MARCH8,RTN4,UBE3B,KAT6A,PHTF2,ZNF248,FXR1" MicroRNA hsa-miR-490-5p:mirSVR_lowEffct hsa-miR-490-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.56E-148 8.75E-145 3.50E-147 3.22E-146 375 1545 "NCKAP5,ACTN1,DSCAML1,ADD1,SORCS1,ADORA1,ADRA1D,ADRB2,NLGN4X,HECW2,KLHL13,PCDH19,CC2D2A,LRRC7,SMIM17,SEMA6A,BCAR3,AMPD2,KIF6,ANK1,LCORL,PPFIA4,PHF12,EPB41L5,ALS2,APP,ASPH,BRINP2,NUMB,ASTN1,DDX3Y,DYNLL1,TMEM108,N4BP2L1,BCL2L2,CFLAR,BMP7,SYNJ1,SGCE,WASF1,KALRN,PTBP2,CAMK2B,VXN,SYT6,BRSK2,LDB2,METTL6,CD38,SEPT7,CDC42,LGI1,DLGAP1,SRSF11,CHM,CHN1,RAB3C,KMT2C,IGFBP7-AS1,ZFYVE9,CLCN3,MYL6B,AKAP5,MFSD4A,HS3ST5,CREB5,GDA,CSF1,RGS6,LRRC3B,CSNK1E,SLITRK5,DZIP3,APPL1,PLCXD3,CTH,CTNND2,RIMS2,DCAF4,USP6NL,SEC14L5,CCDC144A,NOS1AP,CYBB,GAPVD1,ZFYVE16,MATR3,KIAA0586,IST1,DAPK1,SPOCK2,IP6K1,CTIF,SPATA2,YTHDC1,C8orf34,HEPH,MAGI2,DDX46,SMG7,SV2B,SRGAP3,G3BP2,RABGAP1L,WDR20,OLIG1,RPS6KL1,CDON,DNM2,DOCK2,CASP8AP2,DPP6,DNAJB6,ABCC5,DNM1L,ABCC9,EBF1,ATL1,SYT15,YAF2,EGFR,MBNL2,EGR3,EIF4G2,C3orf18,C8orf37,EPB41L1,STX2,EPS8,ZNF549,SRARP,CDKL3,EXTL2,MRVI1,F3,WAC,CEP78,FECH,FGFR1,BAIAP2,SCARA3,HPCAL4,CAP2,IP6K2,SGIP1,SLC37A3,EFCAB2,RASL10A,ERGIC3,DACH2,TMEM151A,GABRA5,GABRG2,GAD1,JPH4,SIGLEC8,DISC1,WASF3,GATM,IGSF5,ALDH1L1,GFAP,HPGDS,RAB30,GLRB,MAP7D2,GNAS,GPD2,PRUNE2,TDRKH,CCDC184,PCLO,RFFL,NR3C1,GRM1,FAM19A2,LINC01551,RABL2A,GUCY1A2,GUCY1B1,IRAK3,UBE2QL1,PADI2,PTGDR2,FRMD3,LINC01102,HNMT,ZDHHC15,SHISA6,IRF8,C2orf72,RBPJ,LRRCC1,NME9,ITPKB,KCNA1,KCNC1,KCNN2,KLC1,IPO5,LIG4,NCOA7,PIK3AP1,CLEC18A,MAN2A2,CHIC1,MEF2C,MEIS1,KITLG,SCAMP5,MID1,MOBP,ERICH3,ZNF680,GIT1,CTNNA3,MXI1,MYO9A,FXYD6,NCAM1,ZC3H12B,NEK1,NEUROD1,OCRL,KCNK10,GLIPR1L2,CNTN3,DPY19L2P2,PCDH9,PCSK2,PDE2A,PDE4D,PDE1B,PIRT,PFKFB4,PIK3R1,PLCL1,PURG,PRIMPOL,LRP12,MAGEL2,POU6F1,MINDY2,PPP3CB,KANSL1,PRKACB,CEP41,PKIA,MAPK8,MAPK9,GON4L,PTPRB,FAM120C,PTPRZ1,TUG1,CEP97,ZNF793,SUSD4,OXR1,RASGRF2,DBX2,KHDRBS2,CRTAC1,REV3L,RFX4,RNASEL,CCDC82,DCUN1D2,PNMA8A,NEK11,RPS6KA2,S100B,DGLUCY,SEMA6D,CSRNP3,SCN2B,SCP2,TNFRSF19,SOX6,CASC3,FOXRED1,PPM1E,ZNF365,BTBD3,LRRC55,SLC8A1,ARHGEF40,SHANK2,KBTBD4,SLC12A2,BTBD7,SPHKAP,GKAP1,MAST1,SMARCD3,SMARCE1,RIMS1,SNAP25,SNRPN,MYO16,EMC1,HECW1,ERC1,PEG10,SPART,NFASC,SRPK2,ATP10B,SMOC1,ZSCAN29,NEK4,SEPT8,CEP68,FGD4,JMJD6,FNDC9,C3orf70,PLCB1,SYN2,SYPL1,SLC37A2,TACC1,TACR1,TAF9,ADGRL3,VWA3A,ACSL6,RPGRIP1L,TCF12,CLASP1,SZT2,SYNE1,FRYL,SIK3,TEK,DICER1-AS1,CRB1,AP4E1,GPR161,SLC44A1,ERCC6L2,RIMBP2,CDK20,WBP2,STXBP4,TRPC1,ZKSCAN5,SGK3,TUBB1,HEPACAM,AMOT,DNAJC12,SLAIN1,CCDC14,VLDLR,WIPF1,CLIP2,GUSBP1,ZIC1,ZIC2,ZIC3,ZNF28,TRIM9,LYPD6,REEP1,POLR3H,FSTL5,SLC30A3,HPS4,SNX27,TMEM163,EPM2A,MARCH8,MSRB3,CPNE4" MicroRNA hsa-miR-155:mirSVR_lowEffct hsa-miR-155:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.72E-148 9.67E-145 3.85E-147 3.55E-146 410 1841 "RALGAPA1,TTYH1,SYN3,ABHD6,TKTL1,KLHL32,ADCY2,GALNT13,SORCS1,ESYT2,BEND6,DPY19L2P4,NLGN4X,AP1B1,ZNF608,GPR158,HACE1,ZNF578,TAOK1,ADGRF5,PCDH10,SYT13,DPP10,LRCH2,C6orf89,UPRT,ALS2,DDO,PPP4R4,CASK,ARHGAP5,ARNTL,ARRB2,ZSCAN18,ASTN1,SLC4A4,ATP2A2,ATP2B1,MPDZ,BCHE,LINC00906,SGCE,OSGIN2,LDLRAD4,CA8,CA12,CALB1,CALM1,SPAG9,TMEM257,LRBA,REPS2,CDH2,ZMYM4,LRRFIP1,ZNF445,CDO1,DIS3L,MS4A7,ZFYVE9,CLCN4,NGEF,FBXO7,HECTD1,CNR1,IQCK,ARMC8,AKAP5,RCHY1,SMARCAL1,PREPL,CREM,CREB5,AKAP12,TRIM69,CRYM,CSF1,FEZ2,OSBPL3,SUSD5,ATRNL1,IPCEF1,VAC14-AS1,SLITRK5,PITPNM3,PLCXD3,SEC14L5,NOS1AP,CYBB,HDAC9,RIPOR2,FRMPD4,RASSF2,KIAA0586,TOMM20,DNAL1,ZEB2,BLOC1S6,RHOBTB1,SPOCK3,RABGAP1L,WDR20,CHRDL1,EXOG,DMD,CPEB2,SLC12A6,CASP8AP2,ABI1,DRP2,RCAN1,PHC2,CNNM1,MRO,ABI2,EGR3,AASS,COPS4,ELAVL4,EPHA5,RTN3,ANKMY1,RRAGB,ADGRV1,EZH1,F3,TAOK3,SCML2,MED12L,POLK,MEX3B,FOXG1,IP6K2,FOXO3,C2orf88,DACH2,FYN,STAG2,GABRA2,HBS1L,RAPGEF6,ARFIP1,MMADHC,USP19,PPARGC1A,TXNL4A,TCERG1,SPIN1,RAB30,PCDH11X,HTATSF1,LUZP2,FERMT2,ADGRA3,STON1,GPR34,NUDT21,GPR37,CECR2,PCLO,RAPGEF4,GRID1,NR3C1,PRDM5,BTN2A1,KIF3A,ZBTB49,TOX2,ELOVL5,GABARAPL2,HMGCR,ZDHHC15,LINC00667,IGF1,C5orf24,ZIC5,DOCK7,LRRCC1,IL12A,ZNF678,LRRTM1,JAK2,KCNA1,KCNA6,KCNC1,KCNJ3,KCNN3,KIF2A,KIF5C,KPNA5,LIFR,SYTL4,MEST,PPM1L,POC1B,ERICH3,COL28A1,SAMD5,SESN3,N6AMT1,MTTP,RSPO2,NDP,NEUROD1,ALDH1L2,NFYA,CNOT4,NOVA2,NPPA,NRCAM,CLDN11,GPR137C,PAH,SNTG1,PAX6,PBX1,DPY19L2P2,PCMT1,PCSK5,PCSK2,PDE1A,PDE3B,PDE4B,PDPK1,CDK14,ABCB1,SEMA5B,PIK3R1,CCSER2,SNX10,XRN1,GPSM2,PLCL1,JAKMIP1,PCDH18,PRIMPOL,PMP22,LRP12,EXOSC10,SCHIP1,ING3,NXPH1,PPARA,TATDN3,PPP2R5C,PPP2R5E,PPP3CA,KANSL1,RANBP3L,PRKAB2,PRKCB,RAB39A,PRKCZ,MAPK9,HYDIN,WBP1L,SYTL2,GDPD2,MDGA2,PIGG,NCR3LG1,PTHLH,STK32A,EML5,PTPRE,ACSM5,PID1,CEP97,ACSS3,ZNF793,SH3TC2,FAT4,RAP1GDS1,ZNF493,OXR1,DBX2,ZDHHC14,MSANTD2,TRIM68,RET,SEC61A2,SLC25A36,RIC8B,RPRD1A,MYH14,GSTCD,ROBO1,TMEM100,UEVLD,SPIN3,GLDN,ACER3,LRRK2,MEG3,RXRA,FAM182A,AP1AR,AMER2,SALL1,MIR124-2HG,SEMA6D,HOGA1,SCP2,GALNT10,SUPT20H,HSPA4L,SGK1,SH3BP2,SH3GL3,KIF16B,DOCK10,SHC4,FNDC3A,SLC1A3,DHX30,SLC6A11,RAB3GAP1,ELMO2,CPEB4,MYH15,DOP1A,PDZD2,KDM3A,MYCBP2,PEG10,KIF1B,C11orf87,SRPK2,ITPRID2,SMOC1,EPB41L3,LARP4,SS18,ELOVL4,DIP2A,KLHL7,FGD4,COBL,ASTN2,TACR1,ANKRD12,PJA1,MCF2L,DNMBP,PDLIM2,AGTPBP1,VWA3A,TCF4,DMXL2,SATB2,TRIM2,PHF24,FAM200B,DICER1,SIRT1,ZFPM2,AP4E1,SLC44A1,TK2,ZFP91,NR2E1,ERCC6L2,HEY2,ZNF384,NR2C2,SYNPO2,TRPC1,TRPC3,ANO5,TMEFF2,ZNF610,UBE3A,SLAIN1,FLRT2,ZNF709,WIPF1,NSD2,XRCC4,PCDH20,ZNF711,MICU3,ATP6V0E2,ZBTB16,TMEM237,AMZ1,DPYSL5,SPIRE1,PLPPR5,SMARCAD1,WNK1,EMSY,CADM2,PRDM2,STOX2,TMEM178A,CIAPIN1,PCDH15,WIPF2,WNK3,WNK2,FZD3,UBE3B,SMIM8,PHTF2,ZNF248,KLHDC1,NETO2,ST8SIA2,SRGAP2B,CPNE4" MicroRNA hsa-miR-16:mirSVR_highEffct hsa-miR-16:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.01E-148 1.13E-144 4.49E-147 4.14E-146 362 1441 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,ACTN1,CSMD2,GALNT13,AXIN2,CDC7,ADRB2,AP2A1,AP2A2,DISP3,LRRC7,ALAD,SRPX,ARHGAP20,OGT,ANK2,CNTNAP1,ALS2,BCAS1,API5,PPFIA3,APP,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,DDX3Y,SLC4A4,TTLL9,MPDZ,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,JAZF1,BTRC,CA8,CACNA1B,CACNA1E,KALRN,PTBP2,NGB,CAMK2D,CANX,VSTM2A,CAST,MAP7,RUNX1T1,ARHGEF1,CDC27,CDC42,CFL2,PPT2,CLCN3,CLCN4,COG1,TPP1,QKI,ARMC8,COL4A5,SLC4A7,SLC4A8,ABI3BP,TBPL1,ACBD5,MYRIP,MFSD4A,HAPLN1,CRYM,LRIG1,FEZ2,MICAL2,VCAN,SOCS5,ERC2,ARHGEF4,USP6NL,ARHGAP32,KATNAL2,GAPVD1,RIPOR2,DCAF8,PHF19,KCTD8,IP6K1,AIF1L,ARMCX2,YTHDC1,JAKMIP2,C8orf34,PLEKHM1,MYEF2,SMG7,SPOCK3,DLG2,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DPYSL2,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SIDT2,RBM12,PHF20L1,MBNL2,ABI2,PLEKHA1,EN2,DENND4A,CEP85L,CDHR1,RTN3,EYA1,NRN1,ACSL4,STRADA,FGFR1,PRKAG2,SUCO,RGPD5,SLC37A3,PDLIM5,CSPG5,NSG1,ARPP21,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,GLS,INSM2,FERMT2,GPD2,PCLO,RAPGEF4,GRM7,RNF165,WIF1,RASSF8,C1orf94,ZHX1,FRMD3,MIER3,SHISA6,HTR2A,MSL1,RBPJ,NIM1K,SCRT2,INPP1,NME9,SLC35G1,KCNC2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,ARHGAP12,PACRG,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MEST,MN1,THYN1,MYBPC1,RTL5,NAP1L2,NDP,NOVA1,SLC11A2,NTRK3,ODF2,OMG,CNTN3,ETFRF1,PCDH9,PCMT1,PDE3B,BEST3,PIK3R1,JAKMIP1,PLP1,PLXNB3,PSAT1,PRRX1,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,PKN2,GDPD1,MASP1,RELN,CNNM2,GDPD2,SNRK,CNTLN,PTCH1,PTHLH,STK32A,ZSCAN32,PTPRD,PEX5,PID1,TMEM255A,FAT4,RAP1GDS1,RBBP6,KHDRBS2,ZDHHC14,RDX,ZYG11B,RET,RFX4,RFX5,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,ARMH4,FBXW7,SYNDIG1,ABCA11P,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN2A,SCN3A,SCN8A,ELMOD1,SLC30A10,COPZ1,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,ST3GAL3,ANKRD6,FAM81A,ARHGEF40,KBTBD4,SLC20A2,SLC22A4,SLN,ZFP1,RCOR3,SNAP25,MBD5,UNC80,RBM34,SON,MYT1L,UNC5B,ZC3H13,KIF1B,TSPYL2,NPAS3,NFASC,TAB2,RGL1,ACSBG1,PRRC2C,SYNE2,C3orf70,SYPL1,SYT1,COBL,SYT4,C12orf76,KAZN,TAF9,WWC1,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,CRB1,TGFBR3,SLC44A1,DDHD1,NR2E1,ERCC6L2,HEY2,TMOD1,TPM2,RUNDC3B,TRPC1,TRPC3,CADM1,AMOT,LGI4,ZNF708,TRIM9,NDRG4,REEP1,EML6,SLC30A4,PMEPA1,LRP8,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,RNF170,SNX14" MicroRNA hsa-miR-1202:mirSVR_lowEffct hsa-miR-1202:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.57E-148 1.44E-144 5.71E-147 5.25E-146 395 1714 "DPF1,RALGAPA1,SERPINA3,KCNH8,ACLY,NCKAP5,CSMD3,ADD2,ADD3,BRAP,ADORA2A,KIAA1211,RNF150,ADRB2,KIDINS220,AP2A2,CC2D2A,PLA2G6,HFM1,SMIM17,ZNF687,PDZD4,DOC2A,OGT,ANK1,ANK2,ANK3,PHF12,CNIH2,SUGT1P4-STRA6LP-CCDC180,UPRT,BCAS1,PPFIA3,SHTN1,SFMBT2,SPTBN4,ZFYVE28,ARHGAP5,PLA2G4C,LINC00173,ASPH,CHRD,DDX3Y,INSYN2B,TMEM108,ALDH4A1,NOL4,ADGRB3,MIR9-3HG,BCL7A,KSR1,BMP7,DST,CASTOR3,JAZF1,SGCE,CFAP410,CA8,DIRAS1,CALM1,TRIM41,CH25H,BRSK2,HIP1R,MAP7,NFS1,CD38,MYOM2,CDH18,CCPG1,CHN1,CASC2,SYNPR,CNOT8,NDST3,COG1,SLC24A2,TPP1,TJP2,HECTD1,NIPBL,CNR1,SUMF2,COL9A1,SMARCAL1,BAG4,MFSD4A,HS3ST5,SEC31B,HAPLN1,CS,SEC24C,MICAL2,CSNK1E,DZIP3,SDC3,NRSN1,PUM1,RUBCN,CYBB,ARHGAP24,INTS1,ELMSAN1,C8orf34,ELMO1,B3GAT3,RUSC2,MED24,PLPPR4,SGSM2,WDR20,ZNF582-AS1,RAB39B,OLIG1,DPH1,DTNA,PHC2,SYT15,PLXNC1,TMEM132E,RCAN2,ANKRD13B,SRRM1,ERBB2,ETV1,FDFT1,TESK2,KAT8,KIAA1109,AMOTL2,FOXF2,SYNCRIP,EVL,SEMA4D,ATP13A4,NOP56,EFCAB2,HVCN1,DACH2,B3GAT1,DOT1L,OGA,MEGF11,DKK3,GAA,HRASLS5,GABRA3,GABRB1,ZMYND11,TUBGCP4,SRCAP,ARFIP1,GFAP,GHR,MALT1,CRCP,GLS,PCDH11X,AIFM3,DCLK2,GPD1,GPD2,PRUNE2,NUDT21,CECR2,C1QL4,RFFL,ADAMTS13,GRM1,GRM2,PRDM5,GRM7,LINC01089,FAM19A2,TMEM25,GSTM5,SOX21,ADAMTS6,FAM222A,PTGDR2,FRMD3,ARHGAP36,HMGCL,TLX1,ZDHHC15,TCEAL6,SHISA6,SMAP1,FAM95B1,LINC00667,DOCK7,USP54,IL11RA,ZNF678,KCNA6,KCNC2,KCNJ3,KCNK1,KIF5C,KIFC3,IPO5,ZFYVE27,MAPT,SYT9,ADAM11,MID1,MITF,AFDN,ERICH3,MSR1,NRBP2,NCAM1,NF1,NFE2L2,NOVA1,DNHD1,NUCB2,P2RY1,ZDHHC22,CDK18,PDE3B,PDE1B,PDGFRA,PFKFB4,ZDHHC8,DUSP26,SEMA5B,XRN1,NLE1,ST8SIA5,PLTP,PLXNB3,MAPKAP1,LRP12,SCHIP1,SDK2,SEPT4,PACSIN1,POLR2F,POU3F2,TMEM235,MINDY2,KANSL1,NKAIN4,VSTM2L,PRKCZ,MASP1,APTX,GDPD2,PTAFR,MTMR10,TMEM260,STK32A,PTPRE,C1orf109,PEX2,NKAIN1,SLC25A48,RAD52,BSDC1,TRIM68,RGS12,GSTCD,CYB561D1,ROBO1,TMEM206,MRAP2,SNX22,EPHA10,GLDN,TCP11L1,MEG3,SOX8,KCNIP3,FAM182A,SALL1,SATB1,SCN4B,LRRTM4,LINC00461,SCP2,TNFRSF19,ZFP30,FAM102A,FERMT1,HKDC1,CHD9,FNDC3A,R3HDM2,SLA,PREX2,BTBD3,DHX30,WDR47,SLC6A11,RAB3GAP1,ELMO2,BTBD7,SLC20A2,ATF7IP,CPEB4,CDK5RAP2,LIMCH1,FAIM2,SNRPN,DOP1A,WDTC1,KIF21B,FNBP1,ZSWIM8,NMNAT2,CLUAP1,ENKUR,KDM4C,ZNF423,CDK19,ZBTB43,NFASC,SRPK2,CLASP2,LARP4,NKAIN2,ST5,MAPK8IP3,RGL1,DIP2A,KLHL7,PRRC2C,ARC,MMS19,KAZN,MTCL1,ALG1,ADGRL3,MGRN1,ANO4,ZEB1,WDR7,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,RNF216P1,ATP13A2,SIRT1,ZFPM2,AP4E1,RELL2,TK2,ZFP91,TMOD1,FAM124A,RIMBP2,CSMD1,RBFOX2,WBP2,FNDC5,UBTF,GORASP1,PITPNB,PLEKHH2,BCL2L13,MEAF6,NPDC1,XRCC4,ZNF28,TRIM9,ZNF540,ZNF70,GPR158-AS1,SLC26A10,CELF4,ZBTB16,TMEM237,SPIRE1,EMSY,MFF,PRDM2,SLC38A1,CSDE1,STOX2,XKR7,C12orf4,ST7,UBE3B,PAK5,NUP214,FXR1,NETO1,JPH3" MicroRNA hsa-miR-485-3p:mirSVR_highEffct hsa-miR-485-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-148 1.86E-144 7.31E-147 6.73E-146 347 1325 "SDE2,NCKAP5,CSMD2,ARID1A,KLHL32,CCDC85A,SLC12A5,SORCS1,AGT,HACE1,OSBPL6,WDR35,CC2D2A,LRRC7,SPARCL1,ARHGAP20,ALK,DPP10,ANK3,SEMA7A,UPRT,GPAM,API5,MIER1,PPP4R4,CASK,NUMB,ASTN1,TMEM108,SLC4A4,RNF182,ADGRB3,SEC11C,CFLAR,SCAPER,CACNA1B,RUNX1T1,LDB2,AIFM1,REPS2,ZMYM4,MAGI1,RCBTB2,SRSF11,CHGA,KMT2C,NRXN1,C4orf33,QKI,TMEM184B,CNR1,AKAP6,MYRIP,ZFP28,PREPL,CREM,CRHBP,GDA,CLIP3,ATRNL1,VCAN,PDE4DIP,APPL1,PHF14,GAPVD1,RIPOR2,SNPH,HDAC4,LIN54,DAPK1,ZEB2,ZBTB24,HEPH,KIAA0753,CEP170,MAGI2,BLOC1S6,ZC3H11A,SMG7,NTM,SGSM2,G3BP2,RABGAP1L,CHRDL1,HS3ST4,NR1D2,PDCD6IP,DTNB,DYRK1A,GOLT1B,EDNRA,ANKRD46,SGK2,YAF2,FAM13A,MRO,TENM1,ELAVL2,TMEM35A,CALCRL,EPB41L2,STX2,ABCA8,WAC,SCML2,DLC1,CEP78,GORAB,FGF1,FGF13,FGFR1,BAIAP2,CAMSAP1,UBE2E3,CAP2,RGPD5,PSD2,SGIP1,EFCAB2,JKAMP,NBEA,PNMA2,MPP6,ZMAT1,MEGF11,GABRA2,GABRG2,GAD1,GAD2,GALC,ZNF274,ZNF559,C15orf41,NEU3,SRCAP,ARFIP1,PPARGC1A,COPS8,TOX3,TNRC6A,ZNF638,RAB40B,GNAS,GPD2,GPM6A,DIPK1C,CECR2,STMN2,GRIA2,GRIA4,GRID1,GRIK2,NR3C1,KAT7,WIF1,BACH2,HNF4G,NEGR1,SMAP1,ZNF181,DOCK7,LRRCC1,INPP1,KCNC1,KCNK2,KCNMA1,KCNN2,LIG4,SYTL4,HECTD2,MATN2,MATN3,MDM4,MEIS1,MEIS2,AFDN,MRPL42,CCDC80,MSR1,N6AMT1,MTTP,MXI1,MYCN,ZC3H12B,NFIX,HCN1,CHAMP1,OGG1,LOC100128398,CLDN11,P2RY1,CNTN3,DPY19L2P2,PDCD2,GPR85,GNG2,PFKFB2,CDK14,ABCB1,PIK3C2A,ST8SIA5,PCDH18,PURG,PMP2,PSAT1,PRRX1,SPATA6,EPB41L4B,PACSIN1,NXPH1,PPM1B,PRKAB2,PKIA,PROX1,PRPSAP2,GDPD1,VPS13C,CNTLN,PLPPR1,MTMR10,PTPRD,PTPRG,PEX5,CEP97,TMEM255A,RAD51D,FAM184A,ZNF493,DBX2,RBBP6,SLC6A15,ERI2,MORC4,GTDC1,FIGN,RFX3,UBR7,RGS7,RGS12,ARHGEF10L,RNF220,RNASEL,CCDC82,ZNF532,TMLHE,CARF,ROBO2,TMEM206,PCMTD2,BAALC,SPIN3,LRRK2,LGR4,HUNK,WLS,ZNF568,MIR124-2HG,LINC00461,ASRGL1,KIF21A,ITSN1,NTNG1,AMBRA1,EPN2,RUFY2,KANSL3,LRRC55,SLC6A11,YPEL4,SLC8A1,LGI3,SMARCE1,LIMCH1,MAPKBP1,CMTR2,SNRPN,UNC80,PDZD2,KIF21B,DOK5,ZC3H13,KIF1B,RBM26,C11orf87,ZNF302,NKAIN2,NEK4,SEPT8,FGD4,PRRC2C,SYNE2,VPS13A,SYPL1,TAC1,TACR1,MTCL1,PJA1,MLST8,TBX15,DMXL2,TCF7L2,ZEB1,TRIM2,WDR7,PCDHGA11,SYNE1,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,AP4E1,C5orf64,ZNF384,TRPC3,PPIL6,TSC1,RFTN2,TMEFF2,SGK3,FAM155A,UGT8,PLEKHH2,VLDLR,TBC1D15,NSD2,XRCC4,ZIC2,ZNF19,ZNF540,EML6,ANKS1B,ZFAND5,PRDM2,LINC02210,TMEM178A,HNRNPA3,PHTF2,ACTR3B,SSPN,RNF146,ZNF30" MicroRNA hsa-miR-1912:mirSVR_lowEffct hsa-miR-1912:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.54E-148 1.99E-144 7.81E-147 7.19E-146 396 1724 "SDE2,CLK4,NCKAP5,CSMD2,CSMD3,KLHL32,ADCY6,ADD1,SLC12A5,GRAMD1B,PWWP2A,RNF150,PTCHD1,BEND6,AP2A2,WDR35,CC2D2A,ALAD,SEMA6A,SPOP,PCDH10,EP400,APBB2,GPAM,VAT1L,USP37,SFMBT2,IGDCC4,LINC00173,MARK4,DACT3,NUMB,CCAR2,ATP1A1,ATP1A2,N4BP2L1,DPY19L3,CARMIL3,ADAM15,SNAI3-AS1,CFLAR,PROM1,KSR1,BMPR1B,SYNJ2,CACNA1G,GPC2,RAB29,CFAP410,CACNA1B,CALB1,DIRAS1,PTBP2,CAMK2B,CANX,KYAT1,CCKBR,CCNH,P2RX6,CBFA2T2,CD38,LRBA,ARHGEF2,CDH18,MAGI1,NOG,CHGA,SOCS6,CHN1,CHN2,DGCR9,CLTC,FADS2,QKI,MAP4K4,TMEM155,ARHGEF6,AKAP7,ARMC8,BTF3L4,COL9A2,AKAP5,SLC4A8,RCHY1,TOGARAM2,MYRIP,IGDCC3,CHD1L,PNKD,CDC42BPB,HAPLN1,ANKRD44,TRIM69,LRIG1,FEZ2,FEZ1,MICAL2,GALNT9,PDE4DIP,PPP1R16B,ERC2,CFAP61,NRSN1,SEC14L5,MYADM,KATNAL2,ARHGAP24,ZNF337,RASSF2,KIAA0586,SPOCK2,C8orf34,TIAM2,GUCD1,SGSM2,CCDC3,KBTBD11,CHRDL1,GRIN3A,DMPK,NR1D2,CDON,DRD1,ECM2,TOM1,DNAJB6,ABCC5,DNM1L,ABCC9,SNX29,EDNRB,ATL1,ANKRD46,SGK2,SUGP2,MRO,MBNL2,USPL1,EPB41,COQ7,RCAN2,DMTN,SEZ6,ANKRD13B,SPEG,VPS26C,RTN3,RCSD1,ANKMY1,F3,REEP2,CLVS1,FABP7,CACNG3,DLC1,FCGR1A,PPP1R1B,GTF2IRD2,FGF1,OLFM1,BAIAP2,PRKAG2,SUCO,MEX3B,PCYOX1,AGAP2,SYNCRIP,SEMA6C,NOP56,C2orf88,DPYSL4,SORBS1,SMC2,PDLIM5,ARFGAP2,ADGRA1,GAB1,GABRB1,GAD2,GAP43,KIAA1841,GATM,NEU3,ALDH1L1,GCNT2,ADAM28,GFRA2,PCDH17,GHR,PPARGC1A,KIRREL3,COPS8,MSL3,PSRC1,PRUNE2,CCDC184,CECR2,PCLO,RAPGEF1,PLCD4,SERP2,GRM7,RNF165,KAT7,ZBTB49,BVES,GPR45,MAN1B1,FRMD3,TNFAIP8L3,BACH2,MIER3,AGFG1,SHISA6,IDH3A,IDH3B,RAB41,C2orf72,IL6ST,SLC6A17,ITGAM,KCNA6,KCNC1,KCNC2,GPR62,KPNA5,LAMP2,STMN1,SYTL4,ZFYVE27,SYT9,LRP1B,MGAT3,ZNF680,MSI1,MTR,RSPO2,MYCN,MYH3,MYO9A,NEXMIF,NAP1L1,SFR1,RCOR2,NF1,NFIX,SLC11A2,NRCAM,NTRK2,NUCB2,LOC100128398,PBX1,PCSK5,PDE3B,PDE4D,PFKFB2,CDK14,NALCN,CAMKV,ZNF655,PSAT1,ING3,RETREG2,MBOAT7,FA2H,SH3KBP1,PPARA,RANBP3L,GRAMD1C,RELN,GDPD2,QRICH1,PIGG,ELOVL2,TMEM260,PTPRB,OCIAD1,PEX5,RAD52,FAM66C,ZDHHC14,TRIM68,PRRT2,RFX4,RGS12,RPRD1A,ZNF532,EXD2,ALG9,ARMC5,CARF,PCMTD2,MRAP2,FBXW7,BAALC,ATP8B4,PAQR6,ABCA11P,KCNIP3,WLS,SCP2,TNFRSF19,SLC30A10,TRIM46,TRA2B,PUF60,ASAP3,MYO18A,FBXO11,SLITRK3,BCAN,ZNF365,PPP4R3A,SMTN,SLC6A9,SLC8A2,SLC9A5,SLC11A1,ELMO2,ZKSCAN3,SORCS3,SMARCD3,IFT122,IGSF9B,RIMS1,SNRPN,PALLD,TMCC1,PDZRN3,MYO16,RBM34,NMNAT2,LHFPL4,CDK19,ZBTB43,TSPYL2,ZNF621,ATP10B,POGZ,SSTR1,MPRIP,ZSCAN29,TTBK2,RGL1,DIP2A,NSFL1C,ARHGEF9,VPS13A,SYN2,MTCL1,ROBO3,PDLIM2,TCF7,TRIM2,CLASP1,AZIN2,RALYL,CCDC173,SIK3,DICER1-AS1,HHIP,RIMBP2,LILRA4,RGMB,SYNPO2,ELP5,STXBP4,EIF4ENIF1,PLEKHH2,BEST1,RICTOR,SLC13A3,ZIC2,PLPP4,TMEM198,ZFAND5,SYNC,WNK1,PRDM2,GDPD5,LINC02210,LMAN2L,ADAMTS9,MDH1B,URM1,NAV2,SLC17A7,KCNAB1,RGS7BP,DOCK8,FAM219B,JMJD1C,ZNF248,RNF170,TTC7A,IFT88" MicroRNA hsa-miR-34b:mirSVR_lowEffct hsa-miR-34b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.50E-148 2.53E-144 9.88E-147 9.10E-146 409 1837 "ACADM,SYS1,ACTN2,KDM5D,ARID1A,TMEM132B,ADCY2,SLITRK1,CCDC85A,GALNT13,ADD2,SNX30,BEND6,SLC44A5,PCDH19,RTL9,WDR35,AK2,TAOK1,LRRC7,SMIM17,ALCAM,BCAR3,PCDH10,FAM135A,ALK,ZFAT,DPP10,MAP4K3,USP28,PHF12,GPAM,DGKD,CACHD1,SHTN1,MIER1,SFMBT2,ARNTL,ZBTB10,DDX3Y,TMEM108,MTMR9,B3GALT2,ATP6V1G2,ATP6V0A1,DCAF5,CACNA1I,CACNA1G,CA8,CACNA1D,CACNB4,CAMK2D,VXN,VSTM2A,RUNX1T1,CERS5,AIFM1,NEURL1,DCLK1,ZMYM4,LARGE1,CACNA2D2,CFL2,JAM2,CLTA,C4orf33,SRP14-AS1,MAP4K4,CNN3,CNTN1,AHCTF1,ZFP28,CREM,CRHBP,CSF1R,ATRNL1,PDE4DIP,FAM169A,PHF14,CTH,DCAF4,USP6NL,CCDC144A,NOS1AP,HDAC9,ZNF337,DNAL1,SPATA2,ELMSAN1,DNAJC6,FBXL5,CEP170,TMEM130,DDX46,ALKBH8,RHOBTB1,SNAP91,EXOG,GRIN3A,NR1D2,DMTF1,CASP8AP2,ABI1,PDCD6IP,RCAN1,ECM2,EBF1,FCF1,SEMA3D,TMTC1,SH3GLB1,ABI2,TMEM35A,USPL1,OLIG2,EPHA5,CEP85L,ETV1,RTN3,SIRPB1,EXTL2,ADGRV1,ARMCX1,CLVS1,FAM198B,ZNF585B,ZIC4,DLC1,ATP8A1,RACK1,CEP78,FDFT1,GORAB,FER,TMEM164,SUCO,MEX3B,CAP2,PCYOX1,SYNCRIP,RGPD5,FLT1,EFCAB2,NBEA,SORBS1,SMC2,TPK1,ATP2C1,ERGIC3,KHDRBS3,CELF1,DACH2,STAU2,MSANTD4,SARAF,AP4B1,DOT1L,BRSK1,ABLIM2,FYN,ZMAT1,MEGF10,GAB1,GABRA3,GABRG2,GAD1,FAM120B,JPH4,IQGAP2,TMEM8B,LRRC37A6P,ALDH1L1,GCNT2,GHR,PPARGC1A,TCERG1,COPS8,GLS,TNRC6A,GNAS,FERMT2,GPD2,TDRKH,FUT10,EML4,GPR37,CECR2,GRB10,GRIA2,GRIK2,GRM1,GRM5,ADAMTS6,GUCY1B1,MAP4K5,NXPH2,MAN1B1,ARHGAP36,BACH2,MIER3,ELOVL5,HMGCL,HMGCR,ZDHHC15,DHX35,ICA1,ZNF181,C5orf24,LRRC25,IL6ST,IL11RA,DIPK1A,INPP5B,ITGAV,SLC35G1,KCND2,KCNK3,LAMP2,HECTD2,FGFBP3,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,POC1B,MMP16,CD200,ERICH3,COL28A1,SCG3,MYO6,ZNF862,NAP1L2,NCAM2,NDUFA5,NEUROD1,NEUROD2,NF1,CNOT4,NTRK2,ODF2,GPR88,CLDN11,PBX1,PCDH9,PCSK5,PDPK1,BEST3,PFKFB2,FAM98B,FAM218A,PLP1,PCDH18,SMIM7,HMGCLL1,PURG,MAPKAP1,SDK2,ING3,RETREG2,SH3KBP1,MINDY2,PPP1R1A,PPP3CA,EPDR1,MAPK8,SLC26A11,PRPSAP2,MASP1,APTX,PLPPR1,OCIAD1,CEP97,SH3TC2,FAT4,ARID4A,RBBP8,ERI2,RFX4,RGS12,SLC25A36,PNMA8A,ROBO1,CCDC102B,EPHA10,RPL15,ATP8B4,ADAL,ACER3,CNTNAP3,LGR4,RPS20,HUNK,FAM182A,S100B,FOXRED2,SEMA6D,SATB1,SCN2B,LRRTM4,ELMOD1,PEAR1,PPM1E,SHMT2,SHC4,MAGI3,AMBRA1,SEC31A,PREX2,SLC2A5,EPN2,LRRC55,SLC6A11,SMARCD3,LIMCH1,KIF13A,SCN3B,DOP1A,CLUAP1,MYCBP2,SPP1,ARHGAP26,ZBTB43,RBM26,NPAS3,ITPRID2,NCDN,STAU1,RGL1,DIP2A,FGD4,ARHGEF9,FNDC9,PLCB1,SYT1,ANKRD28,SYT4,TAC1,ANKRD12,PJA1,CAMTA1,TAF9,TAL1,FAM208A,FBXW11,ACSL6,TCF4,SATB2,SZT2,WDR7,DOCK9,RALYL,AKNA,DICER1-AS1,NACC2,TJP1,TK2,TLL2,BHLHB9,NR2E1,TMPO,BEX4,TPD52,CDK20,C9orf85,ZNF346,PRMT8,AMACR,STXBP4,ANO5,TMEFF2,UBE2H,UBE3A,AMOT,UGT8,DNAJC12,FLRT2,PLEKHH2,ZNF709,BCL2L13,TBC1D15,ZNF781,GUSBP1,SLC13A3,ETNPPL,ZNF24,MICU3,ZNF45,PLPP4,MKRN3,LYPD6,TMEM237,ZNF189,DPYSL5,ZFAND5,PRDM2,GDPD5,GAL3ST3,SLC17A6,FZD3,UBE3B,HNRNPA3,FAM219B,MSRB3,CBLN2,SLC4A10,CPNE4,SPATA13" MicroRNA hsa-miR-32:mirSVR_lowEffct hsa-miR-32:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.53E-148 2.55E-144 9.91E-147 9.12E-146 406 1811 "VWA5B2,AS3MT,ADARB2,ELFN2,CCDC85A,ADD2,ADD3,AXIN2,ERMN,PWWP2A,BEND6,MTA3,INTS2,GPR158,HACE1,OSBPL6,OSBPL8,AK2,LRRC7,BCAR3,PCDH10,UNC79,AMPH,LRCH2,ANK2,PPFIA2,PKP4,ANXA7,APBB2,MAGEE2,DDO,LGR5,AQP4,PPP4R4,CASK,ARHGAP5,RGS20,CDK13,DACT3,ZBTB10,ASTN1,ALDH4A1,SLC4A4,ATP1B3,N4BP2L1,NOL4,DOCK11,BACH1,SNAI3-AS1,MIR9-3HG,ZNF599,FUBP1,BSN,BTRC,VSTM2A,CERS5,SLC16A4,TMEM257,REPS2,CDC42,DCLK1,LGI1,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,AKAP7,PCYT1B,ARMC8,BTF3L4,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,CHD1L,SEC31B,AKAP12,AATK,RGS6,ARHGEF10,SIPA1L1,PHACTR3,PLXNA4,DZIP3,RIMS2,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,SIRPA,DCC,HP1BP3,KIAA0753,DDX46,SNAP91,NTM,NR1D2,DPYSL2,ABI1,MAMLD1,EDIL3,SH3GLB1,EFNB3,FAM13A,PHF20L1,ABI2,RASA4,EIF4G2,SORBS3,TENM1,STARD3NL,CALCRL,EIF1,EMX2,RCAN2,KCNMB2,STX2,SRRM1,EPS8,ERBB4,MRPL37,DNAJC27,EYA1,CLVS1,NSRP1,SCML2,DLC1,RACK1,ST3GAL6,FKTN,TESK2,FER,MED12L,FGF1,FGF13,PRKAG2,UBE2E3,MEX3B,FOXG1,SYNCRIP,FOXO3,SEMA4D,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,STAG2,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,MTHFD2,LRRC37A6P,KIAA1841,GATM,CRCP,TCERG1,DBF4,GLS,PRRC2B,GPM6B,FUT10,STON1,EML4,GRIA4,GRIK2,GRM8,PTPN5,GSTT2,LINC01551,SOX21,GUCY1B1,IRAK3,HMGCR,AGFG1,LRRC75A,EID2B,C5orf24,SCIN,LIX1,INSM1,ZNF385B,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNK1,KCNMA1,KIF5C,KLC1,IPO5,STXBP5,INSYN2,LIFR,PAXBP1,HECTD2,FGFBP3,NCOA7,PACRG,C1orf194,MAP4,MARK3,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MEST,AFF1,MMP16,MYH3,NEXMIF,BEX5,NEK1,NELL2,NEUROD1,NFIA,NFIX,NKX2-2,CNOT4,NPY,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,GLIPR1L2,PCDH8,PCDH9,PCSK5,PIRT,PDGFRA,PDYN,PFKFB4,PFKP,CDK14,CAMKV,XRN1,FAM216A,PCDH18,PMP22,SPATA6,EPB41L4B,FA2H,PPARA,CRLS1,PPP2R5C,PPP3CB,PPP3CC,RANBP3L,PRKAB2,PRKACB,PRKCG,PKN2,EPDR1,DCHS2,LAMA1,SIDT1,MDGA2,CNTLN,ANKHD1,UHRF1BP1,OCIAD1,PTPRG,PEX2,STRC,MARCH1,USP47,RAD51D,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,SLC6A15,GTDC1,RLBP1,SLC25A36,ZFHX4,RERGL,EXD2,ELP2,ACER3,STK32B,LRRK2,RPS20,SYNDIG1,RYR3,ZNF331,CCDC112,SEMA6D,CSRNP3,ATXN1,ATXN7,SCN2A,LINC00461,SCP2,RASA3,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,FBXO11,SYBU,ZNF365,FAM81A,SLC6A1,SEPHS1,NAPB,ATF7IP,SMARCC2,SORCS3,LMBRD1,SNRPN,MYT1L,DOK5,ENKUR,HECW1,SPP1,ZNF423,MCF2L2,RBM26,C11orf87,SRPK2,TAB2,ZC4H2,SS18,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,DDHD2,KLHL4,TBX15,TCF4,SIN3B,DMXL2,NAT16,RALYL,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TLR4,TMOD1,CSMD1,TPD52,TPM1,PDSS1,STXBP4,TSC1,SSBP2,TMEFF2,CADM1,AMOT,SLAIN1,PITPNB,PLEKHH2,RICTOR,XRCC4,ZNF28,ELFN1,NDRG4,SPHK2,REEP1,SMARCAD1,MEIS3,PMEPA1,ZXDA,PRDM2,TMEM178A,SNX27,C12orf4,FZD3,KAT6A,FBXO36,JMJD1C,MSRB3,NHSL1,NETO1,SENP7" MicroRNA hsa-miR-154:mirSVR_lowEffct hsa-miR-154:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.85E-148 4.41E-144 1.71E-146 1.57E-145 355 1391 "SERPINA3,ACADM,ACTN1,SLC25A25,ADAR,ADARB2,TMCC3,ADD3,SORCS1,ERMN,USP31,KIAA1211,ADRA1D,INTS2,OSBPL8,TXNDC16,CDC42BPA,LCORL,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,BCAS1,APP,IGDCC4,ASCL1,CAPRIN2,DACT3,ATP1A2,SLC2A11,SNAI3-AS1,BID,ZNF599,PROM1,FUBP1,CASTOR3,MTMR2,CACNB4,CABP7,KALRN,KYAT1,CCNH,TMEM257,C1orf52,ARHGEF2,CDC27,NOG,SOCS6,KMT2C,KIAA1549L,C4orf33,QKI,TMEM184B,NIPBL,CNTN1,AKAP6,SLC25A27,ZNF521,SLC35F1,FAM171B,RNF14,GDA,SNCAIP,RGS6,CSF2RA,CSNK1G3,VCAN,PLXNA4,SLITRK5,GREB1,RIMS2,ST18,CCDC144A,FGFR1OP2,KIAA0513,CENPL,MATR3,TMEM170A,DAPK1,DNAL1,ARMCX4,DNAJC6,KIAA0753,MAGI2,BLOC1S6,FAM107B,ARNT2,DLG2,DRP2,PDCD6IP,GNE,DNAJB6,DYRK1A,TSPAN5,EDN1,EDNRB,PHC2,FCF1,RBM12,SH3GLB1,PHF20L1,SUGP2,MRO,KMT5B,EPB41L2,RASGRP2,RRAGB,ABCA8,DLC1,ZSCAN30,TESK2,ZNF589,KIAA1109,OLFM1,MEX3B,FOXG1,RGPD5,SEMA4D,SORBS1,TMEM107,FAM49B,CAMKK2,ZNF605,KHDRBS3,CELF1,GPR153,MSANTD4,ZMAT1,STAG2,MEGF10,GABRG1,HBS1L,BRPF3,ZMYND11,RAPGEF6,CYP46A1,PCDH17,MALT1,RND1,GLS,TNRC6A,MAP7D2,LUZP2,GPT2,GPD2,GPM6B,STON1,GPR22,PCLO,NR3C1,GRM3,MFSD2A,LINC01551,SOX21,LINGO1,WIF1,HAS2,FRMD3,HAPLN2,NEGR1,LINC00667,ZNF546,C2orf72,C5orf24,LRRCC1,LIX1,IL12A,ZNF385B,OLFM3,KCNC2,KCNJ3,IPO5,SYTL4,FGFBP3,ARHGAP12,GPR155,MAP2,MARK1,MARK3,MATN3,MBP,CHIC1,LDLRAD3,LRP1B,PPM1L,MITF,CD200,BCO1,CTNNA3,MYO7A,RTL5,NCAM1,ZC3H12B,NCF2,IDNK,NEFH,NEK1,NF1,NME4,NOVA1,SLC11A2,SMIM11A,HCN1,NTRK2,PAH,PCDH8,PDE4B,ZNF655,CCSER2,RETREG1,GPSM2,PLXNB3,PURG,PMP2,TRHDE,PPM1B,KANSL1,PRKACB,EPDR1,APTX,CNTLN,BDNF-AS,PTPN13,OCIAD1,PTPRE,PEX2,ACSM5,PPP2R3C,CEP97,USP47,PLEKHB2,FAT4,FAM184A,RAP1GDS1,KHDRBS2,BSDC1,ERI2,ZDHHC4,RGS10,SLC25A36,ZFHX4,LGI2,CCDC82,SUGCT,RERGL,CARF,ROBO1,NEK11,FBXW7,ACER3,HUNK,CLIP1,RTN1,AP1AR,SATB1,ATXN2,LRFN5,SCN2A,FAM19A1,IL17RB,SOX6,KIF27,PPM1E,KIF16B,DOCK10,CHD9,FBXO11,FNDC3A,ZNF365,RPH3A,BTBD3,KANSL3,LRRC55,RAB3GAP1,BTBD7,ATF7IP,SMARCC2,ANKRD36,RIMS1,TMCC1,SON,PDZD2,SOX10,UNC5B,NPAS3,NFASC,TAB2,SAMSN1,EPB41L3,SS18,SEPT8,SEPT3,STXBP1,KLHL7,VPS13A,C3orf70,MTCL1,PJA1,DDHD2,ADGRL3,VWA3A,DOCK9,PCDHB9,GPRIN3,AHCYL2,HIF3A,TEX15,PMS2CL,SIRT1,ITGB3BP,AKTIP,GZF1,ASXL3,ERCC6L2,HEY2,TMPO,R3HDM1,TPM4,PDSS1,NEIL2,TRO,STXBP4,FNDC5,TMEFF2,SGK3,ZNF610,UGT8,SLAIN1,BCL2L13,MGAT5B,MEAF6,NSD2,RICTOR,ZIC1,ZIC3,ZNF24,TRIM9,PLPPR5,ZFAND5,SMARCAD1,CA10,ZXDA,EMSY,DNALI1,EVI5,CAB39L,PLSCR4,UBE3B,KAT6A,HNRNPA3,FAM219B,ZNF248,SNX14,IFT88,RNF146,PRRT4" MicroRNA hsa-miR-1270:mirSVR_lowEffct hsa-miR-1270:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.42E-148 4.73E-144 1.83E-146 1.68E-145 406 1814 "SERPINA3,CLK4,C3orf14,NCKAP5,ACTN1,SLC12A5,USP31,KIAA1211,DPY19L2P4,AP2A2,OSBPL1A,WDR35,AK2,SEMA6A,ALCAM,PCDH10,DPP10,SUGT1P4-STRA6LP-CCDC180,KCNAB2,ALS2,CACHD1,AMER3,APP,SHTN1,LGR5,SFMBT2,ARHGAP5,MARK4,ASPH,ZSCAN18,ASTN1,ATM,EIF4G3,ATP2B2,SLC2A11,ADAM23,ADAM15,BACH1,LINC00847,RGS9,BID,KSR1,BTK,CACNA1G,BSN,RAB29,CDK5R2,BTRC,CACNA1D,CACNB2,CACNB4,ZNF555,CAMK2D,VXN,SPAG9,P2RX6,TMEM257,C1orf52,REPS2,CDC27,ZMYM4,LARGE1,NUMBL,CHRM1,SYNPR,NDST3,RAB28,FBXO7,TJP2,QKI,SRP14-AS1,HECTD1,CNGA3,FAM149A,TOGARAM2,CLOCK,PREPL,CREM,SLC32A1,SNCAIP,CSF1R,CSF3R,ATRNL1,CNTNAP2,ERC2,APPL1,UBXN2A,PLCXD3,CTNND1,RUBCN,KIAA0408,GAPVD1,TCAF1,RIPOR2,TBC1D5,DGKB,GIT2,DCC,JAKMIP2,C8orf34,ZEB2,CEP170,BLOC1S6,POM121,SMG7,PLPPR4,SV2B,NTM,CCDC3,ARNT2,DLG2,DLX1,GRIN3A,USP3,DNAJB6,DYRK1A,FAM135B,PHC2,SGK2,EGFR,RASA4,GOLGA7,KCNMB2,GPHN,SRRM1,ERBB4,MRPL37,DUSP27,SIRPB1,MRVI1,CACNG3,CHST15,FCGR3A,FCGRT,FKTN,FDFT1,FER,GTF2IRD2,POLR1B,SUCO,PCYOX1,ATP13A4,FLT1,ANKFY1,NOP56,SORBS1,TMEM107,PDLIM5,ATP2C1,GPR153,PNMA2,SARAF,STAG2,GAB1,HRASLS5,GABRA5,CAB39,GAD1,ERAP1,ATP8A2,ACSS1,ALDH1L1,TUBGCP4,SESN1,ADAM28,GHR,BRD8,GLS,TOX3,AIFM3,CBX1,WDFY3-AS2,PRUNE2,CCDC184,GPR22,NUDT21,PCLO,PLCD4,GRID1,CIT,LINC01089,FAM107A,MAEL,IGSF21,LINC01102,AGBL5,HSD17B1,HSF2,LRRC75A,HTR5A,DISP2,LIX1,IL11RA,SLC35G1,METTL21A,CDH20,KCNJ9,KCNN2,CREG2,STXBP5,INSYN2,PIK3AP1,GPR155,MAP4,MAP6,MBD1,MDM4,MEF2C,KITLG,PPM1L,MMP16,MOBP,MOG,JAKMIP3,NRBP2,MYO9A,NEXMIF,ZNF862,NCAM1,NDUFA5,SFR1,NEUROD1,ALDH1L2,NINJ2,NOS1,CNOT4,NOVA1,LRIT2,PCBP3,TBC1D25,OPHN1,KCNK10,PAK3,DPY19L2P2,PCSK5,PDE4D,PDGFRA,GNG2,PFKFB2,PFKFB3,NLGN3,NALCN,ZNF655,CCSER2,MTRF1L,PMP22,MAPKAP1,STRN3,PILRA,PTPA,PPP2R5C,PPP3CC,RASGEF1B,PKIA,DCHS2,MASP1,BCAS3,SIDT1,CNTLN,UHRF1BP1,OCIAD1,FAM120C,TMEM145,ZSCAN2,TUG1,ZNF844,RAB5B,CEP97,TMEM255A,FAM66C,RALGDS,FAM184A,ARID4A,KHDRBS2,RDX,ZMAT4,ERI2,ARHGEF10L,PBRM1,RPRD1A,SUGCT,ALG9,ROBO2,CCDC102B,UEVLD,FBXW7,STK32B,LRRK2,WLS,KCNIP1,TRAPPC13,AP1AR,SALL1,ATXN1,SCN4B,LINC00461,SEC14L1,SOX6,SCAF8,SH3BGR,FHOD3,ABLIM3,SLC6A8,SLC8A3,KBTBD4,NAPB,MTERF2,EPC1,NAXD,ZNF667,SMARCA4,MAST1,CDK5RAP2,RCOR3,ANKRD36,MBD5,CABCOCO1,FAIM2,FAM126B,SCN3B,DOP1A,SOX2,BDP1,SP4,UHRF1BP1L,SPTAN1,KIF1B,CDK19,SPART,C11orf87,TROVE2,ITPRID2,ZC4H2,NKAIN2,INKA2,RGL1,ACSBG1,KLHL7,FGD4,VPS13A,COBL,ANKRD12,PJA1,WWC1,KLHL4,SIN3B,DMXL2,SATB2,SZT2,TMEM151B,OBSL1,PCDHAC2,PUM2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HHIP,AKTIP,MTMR14,HEY1,DAAM2,RIMBP2,NPL,C9orf85,TPM4,RGMB,FNDC5,TSN,ANKRD20A2,TTC3,TMEFF2,SGK3,HEPACAM,RPL7L1,AMOT,FRRS1L,BCL2L13,TBC1D15,LMF1,WIPF1,SF1,ZIC2,FMN2,SMARCAD1,CSDE1,ADAMTS9,URM1,SLC17A7,MVB12B,PDSS2,UBE3B,SMIM8,CASC15,NUP214,FAM219B,TRAM2-AS1,VANGL2,MSRB3,KLHDC1,ST8SIA2,SENP7,JPH3" MicroRNA hsa-miR-26b:mirSVR_highEffct hsa-miR-26b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.72E-148 4.90E-144 1.88E-146 1.74E-145 384 1627 "SDE2,ACADM,CLK4,ACTN2,SORCS1,ERMN,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HECW2,HACE1,TXNDC16,SMIM17,SEMA6A,ALCAM,ANK1,LRCH2,EP400,APAF1,APC,TNRC6C,SHTN1,MIER1,TMEM263,RGS20,CDK13,MARCH3,CCDC74A,ATP1A2,SLC4A4,LINC00847,BID,GPR146,BMPR1B,DST,ST3GAL5,FUBP1,SCAPER,JAZF1,OSGIN2,WASF1,CACNB2,KALRN,VXN,MAP7,KRIT1,USP6,C1orf52,LGI1,LARGE1,SRSF11,SOCS6,CHN2,KMT2C,CLCN3,NRXN1,CLTC,TJP2,DNAJB5,QKI,TMEM184B,CNR1,AKAP7,COL4A5,SLC4A7,AHCTF1,BAG4,ACBD5,CLOCK,C2CD2,RBM39,HAPLN1,GDA,SNCAIP,ARHGEF10,PLXNA4,DZIP3,ERC2,GREB1,CTNND2,ST18,RUBCN,CYBB,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,KCTD8,DAPK1,PITPNC1,JAKMIP2,ZEB2,HEPH,MFAP3L,C2CD2L,PLPPR4,SACS,G3BP2,WDR20,DLG2,EXOG,GRIN3A,DMD,OLIG1,USP3,DPYSL2,PDCD6IP,DTNA,FCF1,KLHL5,TMTC1,FSD1L,RBM12,EGFR,EIF4G2,EIF5,ELAVL2,CALCRL,PAN3,VPS13B,LRRC17,EPHA5,EPHB1,ETV1,FAM198B,RPS6KC1,TMEM132C,EFEMP1,CEP78,GORAB,KIAA1109,FGF14,CAMSAP1,MEX3B,SEMA6C,SEMA4D,SGIP1,SLC37A3,NOP56,UFM1,DACH2,NEURL4,GABRA2,ZNF44,CAB39,FAM184B,ARPP21,GALR1,NEK6,IQGAP2,DISC1,ACSS1,SRCAP,PPARGC1A,GK,GLS,TNRC6A,ZNF638,KCNMB4,GRB10,DIDO1,GRIA4,RFFL,GRM1,GRM7,CLASRP,LINGO1,PSIP1,ADAMTS6,UBE2QL1,ZHX1,LINC01102,MIER3,HNF4G,CELF5,HTR2A,MSL1,ZIC5,RBPJ,IL6ST,DIPK1A,TUBB2B,LRRTM3,KCND2,KCNK1,CREG2,LIG4,SMAD1,MAP2,MARK1,MAT2A,MATN2,MITF,AFDN,MMP16,MOG,CD200,ZNF680,BLOC1S2,ZNF92,MTTP,MXI1,MYO9A,CCDC13,NEK1,CNOT4,SLC11A2,NUMA1,CNTN3,PCDH8,PCDH9,PDE3B,SLC10A4,BEST3,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,FAM216A,PLCL1,PLP1,PCDH18,HMGCLL1,PURG,PMP2,MAPKAP1,ING3,SPATA6,RETREG2,FA2H,MINDY2,PPM1B,PPP2R2B,CRLS1,PPP2R5C,PPP3CB,RANBP3L,CEP41,GRAMD1C,HYDIN,DIRAS2,VPS13C,MDGA2,PIGG,PTK2,PXK,ZSCAN32,PTPN13,PTPRD,FAM120C,TTC13,ZNF615,PPP2R3C,CEP97,TMEM255A,RALGDS,ZCWPW1,RADX,VEPH1,SLC6A15,ZYG11B,UBR7,RGS4,SLC25A36,NUDT11,RPRD1A,ZFHX4,CARF,GSTCD,ARMH4,GLDN,PRR5L,CNTNAP3,LGR4,MEG3,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,SLC30A10,GALNT10,SFPQ,MRAS,KIF27,CHD9,FBXO11,NLGN1,SLC1A6,RUFY2,SLC6A1,ZNF430,CCDC88A,SLCO1A2,TET1,CPEB4,SORCS3,MYH15,SMARCE1,ANKRD36,LIMCH1,CMTR2,PALLD,TMCC1,USP33,MYT1L,ZCCHC24,CAND2,ZC3H13,NPAS3,TAB2,CLASP2,TROVE2,STOX1,EPB41L3,LARP4,ERBIN,STAC2,GSE1,NECAB1,SYNE2,VAMP1,NUDT10,PLCB1,ANKRD28,SYT4,POPDC3,PJA1,DNMBP,FAM208A,ADGRL3,KLHL4,TCEA1,TCF7L2,RALYL,USP32P1,FRYL,C18orf54,AP4E1,ERCC6L2,FAM124A,C5orf64,AMACR,STXBP4,TRPC3,PPIL6,DCBLD1,TSN,ANKRD20A2,RFTN2,TTC3,TTPA,ZKSCAN5,AMOT,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,ZNF24,KCNT2,MKRN3,ZBTB38,ANKS1B,WNK1,SLC30A4,EMSY,PRTFDC1,CIAPIN1,MDH1B,MPPE1,WNK3,PDSS2,FAM13C,JMJD1C,RNF170,VANGL2" MicroRNA hsa-miR-378c:mirSVR_lowEffct hsa-miR-378c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-147 6.31E-144 2.42E-146 2.23E-145 415 1894 "SERPINA3,CLK4,SYS1,KDM5D,GPRIN1,ADAR,ADCY2,CCDC85A,TMCC3,ADD2,ADD3,ADORA1,ADORA2A,RNF150,PTCHD1,KIDINS220,BEND6,MTA3,AP2A2,SNX32,PCDH19,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,VAT1L,PPFIA3,CDC14B,SFMBT2,SPTBN4,ARNTL,MARK4,ASPH,NUMB,N4BP2L1,DNAJC27-AS1,KSR1,GYG2,CACNA1G,RAB29,MMD2,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,CAMK2G,VXN,SYT6,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,IGFN1,GPR37L1,SOCS6,CASC2,MYL6B,NMT2,TJP2,ABCG2,QKI,CNGA3,FHL5,CNTN1,IQCK,FAM149A,AKAP6,COL4A5,ABI3BP,MFSD4A,CHD1L,CLOCK,HAPLN1,CRYM,SNCAIP,TENM4,ATRNL1,NCAN,VAC14-AS1,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,EDRF1,ARHGAP32,HDAC4,EARS2,INTS1,IST1,DGKG,SIRPA,SPATA2,ZEB2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLG2,DLX1,RAB39B,OLIG1,DNM2,DMTF1,SLC25A18,PDCD6IP,EDN1,FAM135B,SGK2,HEYL,RASGRP1,SUGP2,SORBS3,IRAK4,PLEKHA1,MRNIP,TMEM35A,EN2,VPS13B,EPB41,SEZ6,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,CACNG3,PTK2B,CORO2B,ATP8A1,CHST15,ZSCAN30,SEC24B,MED12L,FGR,SUCO,PCYOX1,AGAP3,PSD2,ZCCHC17,ZBED3,APOPT1,NSG2,KBTBD12,B3GAT1,NRG3,DKK3,CHL1,CAB39,FAM184B,HBS1L,BRPF3,GALC,RAPGEF6,IP6K3,GAP43,INPP5K,GBX2,SRCAP,GPR162,ADAM28,GGTA1P,TXNL4A,ZNF638,CBX1,DCLK2,GPM6B,RAPGEF4,GRIK2,GRM7,CLASRP,IL1RAPL1,BVES,IRAK3,LINC01102,SYNPO,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,LIX1,IL6R,TMEM240,KCND1,KCNJ3,KCNK1,KCNK2,KCNN3,KLC1,L1CAM,HECTD2,MAT2A,AQP11,SYT9,MEF2C,AFF1,CCDC80,MSR1,PTOV1,MXI1,MYO7A,RTL5,ZNF862,HNRNPM,NCAM1,NCF2,NELL1,VWA2,NOVA1,DNHD1,CLEC9A,NTRK3,NUMA1,GPR88,PCDH9,PCSK1,CDK18,PDCD2,PDE4A,PDE1B,PIRT,GPR173,TMOD2,PFKFB4,NLGN3,TMIE,ZNF655,CCSER2,XRN1,TMEM38A,PLCB2,SLC25A23,CDIP1,RC3H2,POU6F1,PPARA,PPM1B,CRLS1,PPP3CB,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,WBP1L,CYBC1,FAM120C,PEX2,PEX5,SUSD4,NWD1,RAP1GDS1,RASGRF1,GAL3ST4,ERI2,RFX5,RGS3,PRIMA1,KCTD17,RNF220,GSTCD,YY1AP1,PCMTD2,SNX22,RPL15,SPIN3,KIAA0895L,ATP8B4,GLDN,TCP11L1,SYNDIG1,ABCA11P,AP1AR,MAPK12,ATXN2,SCN2A,PEAR1,SOX6,CASC3,ZNF821,SH3BP2,ITSN1,PPP1R9A,NTNG1,MAGI3,ANKRD6,PAAF1,EPN2,SLC6A1,PKNOX2,LRRC55,SLC8A2,SLC8A3,ARHGEF40,SLC15A2,BTBD7,SLC20A2,SPHKAP,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,WDTC1,SOX3,ZCCHC24,BDP1,NMNAT2,UHRF1BP1L,IDI2-AS1,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SMOC1,SST,SSTR1,LARP4,ZSCAN29,APOM,SEPT8,ADHFE1,STX1A,GSE1,ARHGEF9,SYN2,ANKRD28,MMS19,DDHD2,MCF2L,DNMBP,FBXW11,ANO4,TBX15,SIN3B,TCF7,TCF7L2,TCF12,WDR7,NAT16,PCDHB9,AKNA,TEK,FAM200B,ZNF34,AKTIP,SLC44A1,FBXL16,ARL10,DAAM2,TNFRSF1B,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,ELP5,AMACR,TRPC1,DCBLD1,RUSC1,KCNE5,ANO5,RFTN2,TUB,CLHC1,SLC35A4,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,SF1,ZNF24,KCNT2,LYPD6,ZBTB38,ANKS1B,SH3GLB2,SYNC,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,NAV2,DOCK8,UBE3B,HNRNPA3,PHTF2,FBXO36,NUP214,VANGL2,SSPN,FRMD6,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-196a*:mirSVR_lowEffct hsa-miR-196a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.68E-147 1.50E-143 5.74E-146 5.29E-145 402 1785 "SDE2,SYS1,ACTN1,GALNT16,BRAP,PWWP2A,PTCHD1,SLC44A5,ZNF608,INTS2,KCTD16,NME5,WDR35,AK2,TAOK1,LRRC7,UNC79,CDC42BPA,ANK3,CNTNAP1,APAF1,APBA2,CDC14B,SLC7A14,PDXK,ARHGAP5,RGS20,NUMB,DDX3Y,ATM,ATP1B3,ATP2B2,RIPK1,MPDZ,SEC11C,CFLAR,LINC00906,CACNA1I,CA4,CACNA1B,CALB1,CALM1,CAMK2B,CCKBR,CCNH,MTMR7,INA,LRBA,SEPT7,CDC25B,NOG,GPR37L1,CHM,CASC2,CNOT8,KMT2C,NRXN3,PPT2,KIAA1549L,TPP1,CLTA,QKI,NIPBL,RAB26,CNN3,ARHGEF6,ARMC8,ANKRD35,SUMF2,LETMD1,IFFO1,SLC35F1,PNKD,CREB5,CRY2,GDA,FEZ1,MICAL2,NCAN,VAC14-AS1,PDE4DIP,FAM169A,APPL1,PHF14,ZSCAN23,EDRF1,CCDC144A,NOS1AP,GPRASP1,MYADM,ARHGAP32,TCAF1,RIPOR2,ARHGAP24,LONRF1,INTS1,MAML1,IP6K1,GIT2,YTHDC1,CNIH3,TMEM130,ZC3H11A,DDX46,GUCD1,SRGAP3,WDR20,CPEB2,DMTF1,DPP6,ABCC9,EDNRB,TMTC1,RBM12,YAF2,EFNB3,MBNL2,KMT5B,RASA4,EIF5,ELAVL2,CERCAM,VPS13B,RABEPK,DENND4A,VPS26C,F5,FABP7,SCML2,FCGRT,STRADA,FER,SPSB4,MEX3B,FOXG1,CAP2,FLT1,ANKFY1,HVCN1,PDLIM5,NPTN,KHDRBS3,CELF1,NRG3,TVP23A,GAB1,GABRA2,GABRG1,ZMYND11,SIGLEC8,MTHFD2,ATP8A2,GART,DNER,GFAP,PCDH17,GGT7,GJB1,CRCP,HPGDS,SPIN1,LOXL3,ADGRA3,FUT10,CCDC184,GPR22,EML4,RAPGEF1,RNF165,LINC01551,AP4S1,RABL2A,SOX21,FAM107A,GUCY1A1,RASSF8,BACH2,MIER3,HLF,ZDHHC15,NEGR1,OPALIN,DHX35,SHISA6,LINC00667,DOCK7,KIAA1755,LIX1,INPP5B,TUBB2B,SLC35G1,KCNB1,KCNF1,KIF5C,STXBP5,KTN1,STMN1,ZFYVE27,MARK3,MAT2A,MBNL1,MBP,SYT9,EFHB,MDM4,KITLG,MMP16,JAKMIP3,MYO7A,MYO9A,RTL5,NCAM1,NCAM2,ZC3H12B,NEK1,NHLH1,NOS1,CNOT4,NOVA1,PCBP3,SLC11A2,NTRK2,NTRK3,SETD4,IGSF11,OCRL,OPHN1,CLDN11,P2RX7,PBX1,PDE3B,PIRT,PDGFRA,TMOD2,BEST3,PIK3CD,A2ML1,PLCL1,MTRF1L,PURG,MBOAT7,EPB41L4B,NXPH1,POU3F2,DRAM2,PPARA,TATDN3,PPP2R5C,RANBP3L,CNNM2,SLC22A23,WBP1L,CNTLN,MTMR10,OCIAD1,PTPRG,RIPOR1,RAB5B,PID1,RAD52,FAM66C,RASGRF1,ARID4A,BSDC1,REV3L,ZFHX4,SETD5,EXD2,ALG9,GSTCD,CYB561D1,NEK11,EPHA10,RPL15,ZC3H14,CNTNAP3,RTN1,STX1B,TRAPPC13,RMI1,SATB1,ATXN1,ATXN2,ATXN7,SOX6,TRIM46,CASC3,TRA2B,ZFP30,KIF21A,PPP1R9A,SH3GL3,FUZ,NTNG1,FHOD3,CNKSR2,DZIP1,RUFY2,KANSL3,SLC6A11,SLC8A2,SLC8A1,ARHGEF40,SLC11A1,SHANK2,SLC12A4,BTBD7,EPC1,IGSF9B,RIMS1,MAPKBP1,SNRPN,TMCC1,FAM126B,SCN3B,WDTC1,MYT1L,SOX3,ZCCHC24,KIF21B,BDP1,SP2,ZSWIM8,NMNAT2,ENKUR,EMC1,PEG10,SPTAN1,KIF1B,NFASC,SRPK2,ITPRID2,SSTR1,ZC4H2,SS18,ERBIN,ZSCAN29,CEP68,ADHFE1,STX1A,GSE1,COBL,DDHD2,DNMBP,KIAA1107,FBXW11,KLHL4,DMXL2,TCF7L2,SLC19A3,NSD1,FRYL,HIF3A,DICER1,ZFPM2,ITGB3BP,ARL10,HEY1,TIMP4,ACTR6,ERCC6L2,TMOD1,DAAM2,TPM3,C9orf85,WBP2,PRMT8,STXBP4,TRPS1,TTC3,ZKSCAN5,CLHC1,TUBB1,CADM1,RPRM,UBE2H,PITPNB,MEAF6,BEST1,XRCC4,ZIC3,PLPP4,MKRN3,ZNF177,POLR3H,FSTL5,TMEM198,SMARCAD1,MEIS3,EMSY,LRP8,EVI5,STOX2,XKR7,RNF103,FAM47E,PDSS2,GOPC,FAM13C,CERS6,ZNF248,FAM181A" MicroRNA hsa-miR-497:mirSVR_highEffct hsa-miR-497:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.06E-147 1.72E-143 6.54E-146 6.02E-145 351 1365 "ABCF1,KCNH8,NCKAP5,SYS1,CSMD2,SLITRK1,CCDC85A,GALNT13,ADD2,AXIN2,SLC12A5,ADRB2,OLMALINC,AP2A1,DISP3,LRRC7,ALAD,SMIM17,SRPX,CEP126,ARHGAP20,FAM135A,OGT,ANK2,CNTNAP1,MAGEE2,ALS2,BCAS1,PPFIA3,APP,LGR5,CDC14B,CASK,STK33,ZBTB10,DDX3Y,TTLL9,MPDZ,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,BTRC,CA8,CACNA1B,KALRN,VSTM2A,MAP7,RUNX1T1,ARHGEF1,CDC27,CDC42,TIGD7,PPT2,CLCN3,CLCN4,COG1,QKI,BTF3L4,SLC4A7,SLC4A8,TBPL1,TCEAL2,BAG4,MYRIP,MFSD4A,SEC31B,PREPL,CRYM,LRIG1,FEZ2,MICAL2,SOCS5,ERC2,CFAP61,ZSCAN23,USP6NL,CX3CR1,ARHGAP32,KATNAL2,RIPOR2,DCAF8,TOX,PHF19,KCTD8,ARMCX2,YTHDC1,JAKMIP2,C8orf34,ZEB2,PLEKHM1,FBXO25,SPOCK3,G3BP2,DLG2,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,ABI2,PLEKHA1,PAN3,EN2,RCAN2,GPHN,DENND4A,CEP85L,SPEG,CDHR1,RTN3,EYA1,NRN1,ACSL4,RACK1,FGFR1,SUCO,RGPD5,SLC37A3,PDLIM5,CELF1,CSPG5,NSG1,PHYHIPL,ARPP21,DISC1,SESN1,USP19,PCDH17,GHR,INSM2,GNAS,FERMT2,GPD2,GRIA2,GRM7,RNF165,WIF1,RASSF8,ZHX1,FRMD3,HTR2A,MSL1,RBPJ,NIM1K,SCIN,INPP1,NME9,SLC35G1,KCNC2,KCND2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,SYTL4,ARHGAP12,NCOA7,ZFYVE27,MAP4,LYPLAL1,MARK3,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,THYN1,MYBPC1,RTL5,NAP1L2,NDP,SLC11A2,ODF2,OMG,GPR137C,CNTN3,ETFRF1,PCDH9,PCMT1,PDE3A,PDE3B,PDE4D,SLC10A4,BEST3,PIK3R1,JAKMIP1,PLP1,PURG,PSAT1,PRRX1,MAGEL2,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,GDPD1,MASP1,RELN,CNNM2,SYTL2,GDPD2,SNRK,CNTLN,PTHLH,STK32A,ZSCAN32,PTPRD,PEX5,NKAIN1,PID1,TMEM255A,FAT4,RBBP6,ZDHHC14,RET,RFX4,RFX5,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,ARMH4,FBXW7,SYNDIG1,ABCA11P,ATAT1,KCNIP1,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN2A,SCN3A,SCN8A,LINC00461,ELMOD1,SLC30A10,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,ST3GAL3,ANKRD6,FAM81A,PREX2,ARHGEF40,CCDC88A,KBTBD4,SLC20A2,SLC22A4,SLN,RCOR3,SNAP25,MBD5,SNRPN,UNC80,SON,MYT1L,UNC5B,ZC3H13,KIF1B,TSPYL2,NPAS3,NFASC,SSTR1,NKAIN2,PHLDB1,ACSBG1,PRRC2C,SYNE2,C3orf70,SYPL1,SYT4,C12orf76,KAZN,UNC5D,WWC1,TBCEL,SATB2,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,TGFBR3,DDHD1,ERCC6L2,HEY2,TMOD1,KAT6B,TPM2,RUNDC3B,TRPC1,CADM1,AMOT,LGI4,TRIM9,EML6,ANKS1B,SLC30A4,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-1272:mirSVR_highEffct hsa-miR-1272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.08E-147 2.86E-143 1.08E-145 9.96E-145 378 1585 "RALGAPA1,ABAT,AS3MT,KLRC4,ADD3,KIAA1211,PTCHD1,SLC24A4,MTUS1,GPR158,HACE1,ARHGAP20,DPP10,LRCH2,ANK2,LCORL,USP28,PARG,APAF1,APC,UPRT,AQP4,AQP6,ARNTL,CDK13,PDE8B,ASPH,NCOA1,NUMB,TMEM108,ATM,BARD1,KSR1,JAZF1,C5,CACNA2D1,CACNB2,KALRN,CAMK2D,TRIM41,VXN,RUNX1T1,MTMR7,INA,SYNGR3,CD38,CDC42,CDH8,CDH10,ZMYM4,LRRFIP1,LGI1,MAGI1,TIGD7,CCPG1,COPB2,FOXN3,CHM,SYNPR,CNOT8,RAB28,PLAA,NMT2,NGEF,C4orf33,MAP4K4,CNR1,AKAP6,LETMD1,AKAP5,SLC4A8,ABI3BP,RCHY1,MYRIP,CP,ANKRD44,MROH8,VCAN,NCAN,PDE4DIP,GREB1,CTNND2,NRSN1,RUBCN,CYBB,HDAC9,GPRASP1,ZFYVE16,LIN54,MAML1,IP6K1,DBI,GIT2,YTHDC1,DNAJC6,ZBTB24,HP1BP3,GSDME,DDX46,SACS,WDR20,USP3,SLC12A6,CASP8AP2,ARRDC4,ECM2,ABCC9,GOLT1B,AASDH,EDIL3,ANKRD46,OPTN,KMT5B,ABI2,CALCRL,PAN3,DCTN4,EIF1,LRRC23,GPHN,EYA1,ARMCX1,TAOK3,CEP78,FCGR3A,FCGRT,FDFT1,GORAB,SLC9B2,POLK,HPCAL4,ATP2C1,ERGIC3,AP4B1,NRG3,GABRG1,HBS1L,C15orf41,DISC1,KIAA1841,MYOZ2,IGSF5,GCNT2,SULT1C4,PCDH17,GGTA1P,GHR,RND1,HPGDS,TNRC6A,MSL3,ADGRA3,PRUNE2,TDRKH,EML4,PCLO,GRIA4,GRM1,GRM7,FAM19A2,LINC01551,IRAK3,ZHX1,NCKAP1L,BACH2,HNF4G,HNRNPK,NEGR1,SMAP1,HTR2A,MSL1,C5orf24,IGFBP1,IGSF1,SCIN,LIX1,DIPK1A,ITGAV,OLFM3,KCND2,KCNK2,KIF5C,LAMP2,PAXBP1,HECTD2,NCOA7,LYPLAL1,MBNL1,EFHB,MEIS2,MIA2,PPM1L,POC1B,AFDN,MMP16,WDR49,ERICH3,ADAM22,MSR1,MTTP,MYO9A,NACA,NAP1L2,NDUFA5,NEK1,NF1,NPY,NOVA1,HCN1,NTRK2,SETD4,GPR137C,CNTN3,PBX1,PCDH9,PDE1C,PDE3B,PDGFRA,SLC10A4,BEST3,GDAP1L1,XRN1,MTRF1L,PURG,ING3,MED1,PPP2R5C,PPP3CB,RANBP3L,PRKACB,MAPK8,PROX1,GDPD1,WBP1L,PTHLH,PXK,ZSCAN32,ZIK1,OCIAD1,PTPRD,C1orf109,SLC25A48,USP47,RALGDS,RAP1GDS1,ZCWPW1,OXR1,ZMAT4,RET,GTDC1,RGS3,RGS4,RLBP1,SEC61A2,PBRM1,ZNF532,SETD5,CARF,GSTCD,RORB,NEK11,BAALC,ACER3,ATAT1,AP1AR,AMER2,MIR124-2HG,CSRNP3,ATXN2,SCN3A,FNIP1,TNFRSF19,CASC3,SH3BGR,SH3GL2,ASAP3,CPEB3,NTNG1,HKDC1,AMBRA1,CHD9,SLITRK3,SLC1A6,RPH3A,CCDC88A,ELMO2,SLC20A2,ATF7IP,SLCO1A2,INAVA,SNRPN,PALLD,UNC80,USP33,PDZD2,SP4,HECW1,KDM4C,ZC3H13,KIF1B,NPAS3,CLASP2,ITPRID2,STOX1,SSTR2,ST5,KANK1,SYT11,JMJD6,SYNE2,SYT1,SYT4,C12orf76,POPDC3,ATP11A,ANO4,TCEA1,ACSL6,TCF7,TCF7L2,TCF12,CLASP1,WDR7,SYNE1,PCDHB10,ARHGEF12,GPRIN3,FRYL,TEX15,CRB1,C18orf54,ITGB3BP,SLC44A1,ARL10,TIAM1,HEY1,ASXL3,TPD52,C9orf85,ZNF346,RUNDC3B,AMACR,TSC1,TMEFF2,UGT8,PLEKHH2,NSD2,XRCC4,PCDH20,KCNT2,TRIM9,ZNF540,FSTL5,SLC30A4,EMSY,DNALI1,LRP8,STMN4,PRDM10,RNF103,ADAMTS9,HPS4,PCDH15,GAL3ST3,FAM47E,WNK3,FAM13C,DOCK8,RTN4,UBE3B,PAK5,CASC15,NLRP3,RNF170,SSPN,KLHDC1,FRMD6,SLC4A10" MicroRNA hsa-miR-25:mirSVR_lowEffct hsa-miR-25:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.94E-147 3.90E-143 1.47E-145 1.36E-144 396 1738 "VWA5B2,AS3MT,ADARB2,ELFN2,CCDC85A,ADD3,PWWP2A,BEND6,NLGN4X,MTA3,GPR158,HACE1,OSBPL8,AK2,BCAR3,PCDH10,UNC79,AMPH,LRCH2,ANK2,LCORL,PPFIA2,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APBB2,MAGEE2,DDO,AQP4,PPP4R4,CASK,RGS20,CDK13,DACT3,ZBTB10,NCOA1,ASTN1,TMEM108,ATP1A2,SLC4A4,ATP1B3,BACH1,FUBP1,BSN,CDK5R2,BTRC,VSTM2A,SLC16A4,TMEM257,CDC42,LGI1,L3MBTL4,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,NGEF,MAP4K4,LY86,AKAP7,PCYT1B,ARMC8,BTF3L4,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,CHD1L,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,SIPA1L1,NCAN,PHACTR3,DZIP3,RIMS2,PPP6R2,ECE2,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,SIRPA,DCC,DNAJC6,HP1BP3,KIAA0753,DDX46,SNAP91,NTM,WDR20,NR1D2,ABI1,MAMLD1,ABCC5,EDIL3,EFNB3,FAM13A,PHF20L1,ABI2,EIF4G2,SORBS3,TENM1,EML1,STARD3NL,EIF1,EMX2,EPHA5,KCNMB2,EPS8,ERBB4,MRPL37,DNAJC27,CLVS1,ZIC4,SCML2,DLC1,RACK1,ST3GAL6,FKTN,TESK2,GORAB,FER,MED12L,FGF1,FGF13,PRKAG2,SCARA3,MEX3B,FOXG1,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,ADGRA1,STAG2,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,MTHFD2,LRRC37A6P,KIAA1841,GATM,ADAM28,CRCP,DBF4,GLS,ZNF638,DCLK2,PRRC2B,GPM6B,FUT10,EML4,GRIA4,GRIK2,GRM8,GSTT2,LINC01551,SOX21,GUCY1B1,ZHX1,PTGDR2,HMGB1,HMGCR,LRRC75A,HTR5A,EID2B,C5orf24,SCIN,INSM1,ZNF385B,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNMA1,KIF5C,IPO5,STXBP5,INSYN2,PAXBP1,HECTD2,FGFBP3,NCOA7,PACRG,C1orf194,MAP4,MARK3,TM6SF1,MEF2C,MEIS1,AFF1,MMP16,MYH3,BEX5,NAP1L1,NAP1L2,NEK1,NELL2,NEUROD1,NFIA,NFIX,NKX2-2,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PIRT,PDGFRA,PDYN,PFKFB4,CDK14,PIK3C2A,XRN1,FAM216A,PCDH18,PMP22,SPATA6,EPB41L4B,PPARA,CRLS1,PPP2R5C,PPP2R5E,NKAIN4,RANBP3L,PRKAB2,PRKACB,PRKCG,PKN2,EPDR1,DCHS2,LAMA1,SIDT1,MDGA2,CNTLN,OCIAD1,PTPRG,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,RLBP1,SLC25A36,ZFHX4,RERGL,EXD2,C12orf49,ELP2,ACER3,STK32B,LRRK2,LGR4,RPS20,SYNDIG1,RYR3,ZNF331,CCDC112,MIR124-2HG,SEMA6D,CSRNP3,ATXN7,SCN2A,LINC00461,RASA3,NLGN4Y,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,SYBU,ZNF365,FAM81A,SLC6A1,SEPHS1,ATF7IP,SMARCC2,SORCS3,LMBRD1,SNRPN,MYT1L,SOX11,DOK5,NMNAT2,ENKUR,HECW1,ZNF423,TSPYL2,MCF2L2,RBM26,SRPK2,TAB2,ATP10B,EPB41L3,ZC4H2,SS18,ERBIN,ZSCAN29,SEPT8,DIP2A,STXBP1,VAMP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,DDHD2,KLHL4,TBX15,ATMIN,TCF4,DMXL2,ZEB1,NAT16,RALYL,GPRIN3,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TLR4,TMOD1,TPD52,TPM1,METTL3,PDSS1,STXBP4,TSC1,ANO5,SSBP2,CADM1,PITPNB,PLEKHH2,XRCC4,ZNF28,TRIM9,ELFN1,SPHK2,REEP1,MEIS3,ZXDA,TMEM178A,C12orf4,EPM2A,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,FAM198A,SPATA13,SENP7" MicroRNA hsa-miR-302e:mirSVR_lowEffct hsa-miR-302e:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.29E-147 5.22E-143 1.96E-145 1.81E-144 405 1817 "ABAT,KCNH8,ABR,NCKAP5,ACTN2,CSMD3,ADCY5,SLITRK1,ADCY6,ADD1,GRAMD1B,ESYT2,OSBPL8,PLA2G6,HFM1,C1QTNF3,LRRC7,SPARCL1,SRPX,ARHGAP20,SYT13,AMPD2,AMPD3,SEMA7A,CCDC146,USP28,PPFIA1,ANXA7,APC,SHTN1,AQP4,PPP4R4,ARSE,CDK13,CAPRIN2,ASTN1,INSYN2B,ATP1B3,ATP2B2,NOL4,LDHD,DST,SYNJ2,ARHGEF7,AP1M1,C5,GPC2,MYRF,CALM1,PTBP2,NGB,CAMK2D,PRC1,CDC27,DCLK1,LGI1,LOC730101,DLGAP2,TIGD7,CCPG1,B4GALT6,KMT2C,ZFYVE9,PPT2,KIAA1549L,NIPBL,ARMC8,SLC25A27,SUMF2,LETMD1,SLC4A8,IFFO1,AHCTF1,ZNF521,HS3ST5,FAM171B,C2CD2,CREB5,GDA,ABCG1,CSF1,RGS6,CSF2RA,CNTNAP2,FAM169A,PHF14,CFAP61,DCAF4,RUBCN,CX3CR1,CCDC144A,DCAF8,HDAC4,ZFYVE16,RASSF2,TMEM170A,AIF1L,SIRPA,YTHDC1,C8orf34,ZEB2,HEPH,MFAP3L,FBXL5,KIAA0319,CEP170,PLPPR4,WDR20,CCDC3,GRIN3A,DNM1,USP3,CD99L2,DPYSL2,MAMLD1,DNAJB6,DNM1L,KRBA2,KLHL5,TMTC1,SH3GLB1,EFNB3,PHF20L1,SUGP2,MBNL2,BSCL2,PAN3,RCAN2,SLC43A2,TMEM74,CDKL3,ETV1,CD320,EZH1,F5,WAC,CACNG3,ACSL4,TAOK3,EFEMP1,TOMM40L,PRMT5,TESK2,FECH,FER,FGFR1,FOXF2,FOXO3,SEMA4D,FLT1,C2orf88,NBEA,ZBED3,SPECC1,PDLIM5,ARFGAP2,DACH2,ST6GALNAC3,PHYHIPL,GAB1,GALNT15,DENND2A,HBS1L,GALC,ERAP1,INPP5K,GCNT2,PCDH17,MALT1,GLRB,TOX3,LUZP2,DCLK2,GPD1,PRUNE2,DIPK1C,TDRKH,RAPGEF4,GRIA2,RFFL,RNF165,ZBTB49,BVES,AP4S1,RASSF8,HAS2,ZHX1,NXPH2,PTGDR2,FRMD3,LINC01102,MIER3,HLF,HMGCL,HNF4G,HNMT,HPCA,HTR2A,EID2B,C5orf24,IL6ST,ITPKB,METTL21A,KCNK2,KHK,KIT,VWA5A,PIK3AP1,MAN2A2,MAP4,MBP,CHIC1,MDM4,MEF2C,MEIS1,KCTD6,MKLN1,XRRA1,MOBP,ERICH3,SESN3,BCO1,THYN1,N6AMT1,MTR,MXI1,RTL5,ZNF862,MYT1,FXYD6,SFR1,NFIA,ALDH1L2,NFYA,NOVA1,PCBP3,TBC1D25,ODF2,OPCML,GPR137C,CNTN3,PRTG,PDE3B,PDE4D,PIRT,GPR85,OLA1,NLGN3,NALCN,FAM218A,PKD1,ZFYVE21,TMEM38A,GPSM2,PLCB2,EPB41L4B,POU6F1,PPM1B,PTPA,PPP2R5E,KANSL1,PKIA,PRKCZ,MAPK9,HYDIN,GDPD1,SLC22A23,SIDT1,MDGA2,PIGG,UHRF1BP1,PTK2,PTPRG,FAM120C,TMEM231,QDPR,RAD52,RALGDS,ATG16L1,RAP1GDS1,RASGRF1,RASGRF2,RBBP6,ZDHHC14,PRRT2,PRIMA1,ARHGEF10L,SLC25A36,NUDT11,PBRM1,LGI2,SETD5,ALG9,CCDC25,RORB,UEVLD,ACER3,MAP6D1,PTGR2,MEG3,HSD11B1L,RTN1,TMEM156,HOGA1,LRRTM4,LINC00461,FNIP1,SMPD3,SOX6,SUPT20H,HSPA4L,ZFP30,SLC1A6,URGCP,SLC6A9,SLC6A11,SLC8A3,CCDC88A,SLC11A1,BTBD7,SLC20A2,ABTB1,SMARCD3,SMARCE1,MBD5,KIF13A,SNRPN,PALLD,TMCC1,USP33,PDZD2,WDTC1,SOX1,TRERF1,ZCCHC24,BDP1,TEX2,IQSEC2,NPAS3,SRPK2,PBLD,ERBIN,CEP68,DIP2A,ADHFE1,SEPT3,FNDC9,SYT1,COBL,KAZN,DDHD2,ADGRL3,AGTPBP1,ATMIN,EHBP1,ZFP90,TRIM2,SZT2,SYNE1,RALYL,FAM189A1,PCDHB4,TNS2,TEX15,PMS2CL,GPR161,GALNT17,HEY2,RIMBP2,R3HDM1,TPM2,NR2C2,SYNPO2,METTL3,TMEFF2,UBE3A,SLAIN1,CCDC14,NSD2,PCDH20,ZNF711,TRIM9,FSTL5,ZSCAN26,DPYSL5,PLPPR5,UPF3A,CA10,EMSY,MFF,ADAMTS9,HPS4,VPS35L,PCDH15,WIPF2,WNK2,SLC17A6,PARP11,C12orf4,PDSS2,EPM2A,JMJD1C,RNF170,NETO2,ST8SIA2" MicroRNA hsa-miR-370:mirSVR_lowEffct hsa-miR-370:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-146 5.68E-143 2.13E-145 1.96E-144 425 1994 "DGCR6,KCNH8,SYN3,ASIC1,NCKAP5,SYS1,ACTN2,FAM43B,XKR4,ADCY6,PWWP2A,CC2D2A,AK2,ZNF578,TAOK1,ARHGAP20,CARNS1,CDC42BPA,EP400,MYH7B,USP28,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,APLP1,APOC1,CACHD1,TNRC6C,USP37,CPNE5,AQP6,CDK10,SFMBT2,TMEM263,ARHGDIA,DACT3,DDX3Y,TMEM108,ATP1A2,SLC2A11,B3GALT2,ADAM15,BACH1,LINC00847,SEC11C,RGS9,BCL7A,DCAF5,CFLAR,KSR1,SYNJ1,SYNJ2,MTMR3,JAZF1,CA12,CACNA1D,CACNB2,KALRN,TRIM41,CANX,VXN,SPAG9,RUNX1T1,ZNF501,SCARB1,SYNGR3,CDH8,TIGD7,CCPG1,NOG,CRLF1,SRSF11,ASIC3,SYNPR,RAB33A,QKI,MAP4K4,AKAP5,SLC4A8,CLOCK,CREM,SH2B1,HAPLN1,CRY2,ANKRD44,CS,MICAL2,GALNT9,VCAN,RASGEF1C,PLCXD3,CTH,GREB1,CTNND2,RIMS2,ST18,EDRF1,ECE2,CYBB,ARHGAP32,ZFYVE16,EARS2,TM9SF4,LIN54,MAML1,TMEM170A,DAPK1,TOMM20,SPOCK2,IP6K1,GIT2,SPATA2,C8orf34,HEPH,TIAM2,FBXL5,TMEM130,FBXO25,GUCD1,ALKBH8,POM121,RHOBTB1,SGSM2,RABGAP1L,TMCC2,WDR20,CCDC3,KIF19,DLG2,DNM2,ATN1,DTNA,DTNB,ECM2,E2F6,EDN3,PHC2,SYT15,RASGRP1,EGFR,GOLGA7,KCTD3,COPS4,ELAVL2,PLEKHA1,EML1,PAN3,EN2,EPB41L2,MTSS1L,SEZ6,SRRM1,ZNF549,CDHR1,ANKMY1,KATNAL1,ARMCX1,CHST15,FCGR3A,TOMM40L,SLC9B2,FGF14,TMEM164,POLK,SEMA4D,FLNC,FLT1,EFCAB2,ZNF605,NSG2,HHIPL1,ILDR2,GAD1,HBS1L,ZMYND11,ZNF274,NEK6,GHDC,NCKAP1,TMEM8B,DISC1,ATP8A2,ALDH1L1,ARFIP1,FREM1,CSDC2,LYVE1,RUNDC3A,ZNF276,PCDH11X,ZNF638,GNAS,ZNF782,PSRC1,GOLGB1,STON1,EML4,RAPGEF4,RAPGEF1,CACFD1,CIT,CLASRP,RNF165,PTPN5,TMEM25,LINC01551,RABL2A,ADAMTS6,FRMD5,ELOVL5,HMGB1,IGFBPL1,HNRNPK,DHX35,HSP90AA1,ICA1,EID2B,RBPJ,LRRCC1,DISP2,IL6ST,BRINP3,KCNC1,KCND2,GPR62,KCNJ9,KCNK1,GATD1,KIF5A,KIF5C,A1BG-AS1,IPO5,STXBP5,LIG4,PAXBP1,SMAD1,MAP4,MBD1,SYT9,MEIS1,MEST,AFF1,MMP16,GIT1,DBNL,NRBP2,MT3,N6AMT1,MTR,RSPO2,LYRM9,LAYN,MYO6,MYO9A,FXYD6,NDUFA5,NEFM,NEUROD1,SMIM11A,NTRK2,NUMA1,TBC1D25,OCRL,ODF2,LOC100128398,KCNK10,PAK3,PDE1C,GNG2,PFKFB4,XRN1,PLIN1,HMGCLL1,PNMA3,POLR2F,DRAM2,PPP2R5E,RASGEF1B,RAB39A,SLC22A23,WBP1L,CYBC1,DEF8,MTMR10,PTPRE,NKAIN1,TUG1,CEP97,CCDC40,RBBP6,BSDC1,RFX2,RGS3,RGS4,RNF220,ZFHX4,C12orf49,KLHDC8A,ARMC5,CCDC25,ELP2,RPE65,NEK11,BAALC,SPIN3,KIAA0895L,GLDN,STK32B,RTKN,ZNF568,ZNF331,SARS,SCN2B,SCN7A,PEAR1,TRIM46,GALNT10,STUM,FOXRED1,MRAS,SCAF8,NLGN4Y,FAM102A,HKDC1,ST6GAL1,ST3GAL3,ANKRD6,NUBPL,SLC1A3,DHX30,SLC9A5,TMEM132D,SLCO1A2,TET1,ZFP1,GKAP1,SORCS3,MYH15,KDM4B,WDTC1,ZSWIM8,CLUAP1,ENKUR,IZUMO4,ZC3H13,DBNDD2,KIF1B,CLASP2,ZC4H2,SSPO,INKA2,MPRIP,STAU1,NEK4,SEPT8,PHLDB1,MLC1,NUDT10,COBL,KAZN,SEMA4A,TAF9,EXOC7,ANO4,TCF7L2,TCF12,SYNE1,NAT16,TMEM151B,RALYL,USP32P1,CYB561A3,DICER1,ZFPM2,ITGB3BP,SLC44A1,THRA,TJP1,TLL2,NR2E1,FAM124A,RIMBP2,R3HDM1,TP53BP2,CDK20,TPM4,ELP5,AMACR,KCNE5,TMPRSS5,TSC1,HEPACAM,UBTF,SLAIN1,VAV2,VIPR2,VLDLR,BEST1,WNT7A,KLC2,XRCC4,ZFP37,ZIC2,ATP6V0E2,AMZ1,PLPPR5,STMN4,PCDH15,GAL3ST3,NAV3,URM1,FIP1L1,CAB39L,ITM2C,FAM47E,WIPF2,MVB12B,MRPL47,RTN4,KAT6A,SMIM8,FBXO36,NUP214,FAM219B,MSRB3" MicroRNA hsa-miR-9*:mirSVR_highEffct hsa-miR-9*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-146 5.81E-143 2.17E-145 2.00E-144 386 1655 "CLK4,NCKAP5,KLHL32,SORCS1,ERMN,PWWP2A,PTCHD1,ADRA1D,ADRB2,MTUS1,GPR158,OSBPL1A,OSBPL8,AMPD3,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,APBA2,USP37,MIER1,ARHGAP5,CDK13,CCDC74A,ASPH,ZBTB10,SLC4A4,TTLL9,SNAI3-AS1,ADGRB3,DCAF5,BID,MTMR2,JAZF1,SGCE,OSGIN2,WASF1,CA8,KALRN,CANX,SLC25A14,SYT6,CAST,CBLN1,LDB2,KRIT1,USP2,C1orf52,REPS2,L3MBTL4,MAGI1,CFL2,CHM,CASC2,SYNPR,CLCN3,NRXN1,TJP2,NIPBL,IQCK,SLC32A1,ABCG1,MICAL2,CSNK1E,OSBPL3,CSNK1G3,APPL1,PHF14,PNPLA8,PUM1,CYBB,HDAC9,GPRASP1,PHF19,ZFYVE16,ZNF337,KIAA0586,KCTD8,DAPK1,SIRPA,ARMCX2,ZEB2,HP1BP3,ZC3H11A,RHOBTB1,G3BP2,RAB39B,DMD,CPEB2,RCAN1,DTNA,DNAJB6,ABCC5,DNM1L,ABCC9,E2F5,SNX29,FAM135B,ANKRD46,HIPK3,FSD1L,YAF2,PHF20L1,APH1A,EGFR,EGR3,ELAVL2,PAN3,VPS13B,SRRM1,EPS8,ABCA8,PTK2B,RACK1,CEP78,FCGR3A,GORAB,FER,POLR1B,SPSB4,FGF14,PRKAG2,FHL1,POLK,MEX3B,NELFCD,JKAMP,PDLIM5,CAMKK2,DACH2,STAU2,MSANTD4,ZNF512,STAG2,GABRA1,GABRA2,CHL1,AHCYL1,ZMYND11,GALR1,C15orf41,ACSS1,LRRC37A6P,CPLX1,DNER,ARFIP1,SESN1,ADAM28,MMADHC,GHR,GK,COPS8,GLS,INSM2,GNAL,GPM6B,GPR17,GPR19,EML4,RAPGEF4,GRIA2,KIF3A,BVES,FAM107A,GUCY1B1,ZHX1,NXPH2,ACOT7,HMGB1,HNF4G,ZDHHC15,HSF2,HTR5A,IFI16,ZNF181,SOWAHA,C5orf24,RBPJ,DOCK7,ZNF678,INSM1,LRRTM1,ITGAV,OLFM3,KCNN2,IPO5,LAMP2,NCOA7,PIK3AP1,MAP4,MARK1,KITLG,MITF,MN1,ZNF680,JAKMIP3,MXI1,MYO9A,NEXMIF,NAP1L1,NAP1L2,NDP,SLC11A2,OGDH,OLR1,P2RY1,PAK3,PCSK1,PDE3B,PDGFRA,PDPK1,PFKFB2,OLA1,NALCN,ZNF655,ZFYVE21,RETREG1,PLIN1,PLP1,HMGCLL1,STRN3,RC3H2,LRP12,SPATA6,EPB41L4B,SH3KBP1,POU3F2,MED1,MINDY2,CEP41,PKN2,PRKCZ,MAPK4,MAPK9,SAMD9,CNTLN,PLPPR1,TMEM260,PTPN13,PTPRB,OCIAD1,PTPRG,PTX3,PEX2,ZNF615,PID1,TMEM255A,RBBP6,RADX,VEPH1,KHDRBS2,RDX,MORC4,FIGN,RGS10,RLBP1,SEC61A2,SLC25A36,RPRD1A,ZFHX4,CCDC82,CARF,GSTCD,MRAP2,ADAL,ACER3,RPS6KA2,LRRK2,WLS,CLIP1,RTN1,RYR3,AMER2,ATXN2,SCN7A,ZFP2,HSPA4L,CPEB3,FHOD3,ZNF365,RAB3GAP1,SHANK2,SLC12A2,SLC15A2,BTBD7,SORCS3,SMARCE1,CMTR2,SNRPN,SON,SOX1,SP4,CLUAP1,EMC1,ZC3H13,MCF2L2,LMO3,C11orf87,CLASP2,POGZ,ITPRID2,LARP4,LRRC4,NXT2,CEP68,PHLDB1,SEPT3,SYT11,SYNE2,SYT1,SLC37A2,ATP11A,PJA1,DDHD2,TBCEL,TCEA1,TRIM2,TCF12,WDR7,SYNE1,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,C18orf54,ITGB3BP,AKTIP,TIAM1,HEY1,TK2,ASXL3,DDHD1,TLL2,NR2E1,TMOD1,TPD52,TPD52L2,TPM3,TPM4,TRIO,TRPS1,ANO5,ZKSCAN5,TUBB1,FAM155A,UBE2H,UGT8,FLRT2,PLEKHH2,MEAF6,TBC1D15,WIPF1,GUSBP1,ZFP37,ZNF19,ZNF24,FMN2,LYPD6,ZNF184,EMSY,CADM2,CSDE1,STOX2,RNF103,NAV3,PPP1R3F,KCNAB1,FAM47E,PARP11,PAK5,PHTF2,FBXO36,CASC15,KLHDC1,FXR1,FRMD6,NETO2,DPF3,CBLN2,SOCS4,FAM198A" MicroRNA hsa-miR-502-5p:mirSVR_lowEffct hsa-miR-502-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-146 6.89E-143 2.56E-145 2.36E-144 403 1801 "ABAT,KCNH8,ABHD6,EMILIN3,NCKAP5,CSMD2,NDRG3,GALNT16,TMCC3,ADD1,KIDINS220,NLGN4X,AP2A2,GPR158,GOLGA7B,FAM135A,AMPD2,CCDC146,SUGT1P4-STRA6LP-CCDC180,PARG,DGKZ,AMER3,PPFIA3,AQP4,MIER1,RGS20,ARSF,MARCH3,NUMB,EIF4G3,CADM3,NOL4,CARMIL3,LDHD,C5,IL33,CACNB2,CALM1,VXN,VSTM2A,CARS,RUNX1T1,CBR1,CBS,RGN,TMEM257,CD38,ZBED1,CLGN,NUMBL,COPB2,CHM,CHN2,CHRNB2,LHX2,KMT2C,RAB28,PPT2,NRXN1,TPP1,MYL6B,DGCR9,TMEM184B,MAP4K4,AKAP6,RCHY1,COX4I1,IGDCC3,CPS1,PNKD,C2CD2,ANKRD44,RGS6,FAM169A,CTH,CTNND1,ST18,NOS1AP,ARHGAP32,FRMPD4,KIF26A,DGKG,TOMM20,SCRN1,IP6K1,GIT2,ZEB2,ZBTB24,RUSC2,KIAA0319,KLHL3,FBXO25,CHRDL1,OLIG1,DNM2,SLC12A6,CASP8AP2,ACOT8,ECM2,MAMLD1,SGK2,FCF1,HEYL,GPR61,EGFR,ABI2,CERCAM,ELN,C3orf18,EML1,EPB41,EPB41L1,EPHB1,KCNMB2,ENPP6,EPS8,ERCC2,DENND4A,CDHR1,MRPL10,ADGRV1,REEP2,TAOK3,RACK1,TESK2,ZNF589,FER,FGF1,FGF13,POLK,UBE2E3,SEC23B,PCYOX1,SYNCRIP,SEMA4D,WDR83,TMEM107,ZBED3,APOPT1,ARFGAP2,ZNF605,PRELID3A,DLL3,KBTBD12,TPPP3,DOT1L,ZMAT1,MEGF11,MEGF10,ARPP21,ERAP1,DISC1,ATP8A2,DNER,ALDH1L1,CYP46A1,ADAM28,PPARGC1A,LYVE1,RUNDC3A,ZNF276,CRCP,GLI2,TNRC6A,KDM2B,OS9,LOXL3,GNAS,GOLGB1,GPD1,GPD2,PCLO,STMN2,TPPP,GRIA1,GRIA2,GRIK2,PRDM5,GRM7,LINC00839,CLASRP,SLC2A6,MAP4K5,MAEL,HAS2,TOX2,C9orf129,HSP90AA1,HTR2A,ATCAY,MYLK2,RBPJ,NIM1K,KCNA1,KCNA6,KCNC2,A1BG-AS1,LAMP2,PACRG,CLEC18A,LOC100128239,ZFYVE27,MATK,MATN3,MBNL1,MBP,TM6SF1,MEIS1,SRSF12,KCTD6,SCAMP5,WDR49,CD200,SESN3,JAKMIP3,PTOV1,CTNNA3,MTR,HS6ST3,RTL5,FXYD6,NEFH,NEUROD2,NF1,ALDH1L2,NFYA,NODAL,SLC11A2,OCRL,P2RX7,ZNF827,ZDHHC22,SNTG1,PAK3,PBX1,PCSK5,PCSK2,PDE1A,SERPINI1,PLCB2,PLP1,HMGCLL1,PLXNB3,PNMA3,STRN3,PSAT1,PRRX1,ING3,RETREG2,EPB41L4B,PACSIN1,CCDC144B,PPP3CA,PRKAB2,PIGG,CNTLN,UHRF1BP1,BDNF-AS,ZIK1,PTPRB,C1orf109,PTPRZ1,NKAIN1,PPP2R3C,ZNF793,SLC25A41,ENOX1,RASGRF2,RLBP1,RIC8B,RNASEL,DCUN1D2,RORB,ZC3H14,GLDN,MEG3,ABCA11P,ATAT1,WLS,FAM182A,RMI1,PRCD,TRIM46,TRA2B,SCAF8,ZFP30,ITSN1,SH3GL3,CNKSR2,SLC1A7,FAM214B,SLC6A8,SEPHS1,SLC8A1,RAB3GAP1,SLC9A5,SLC14A1,SLC22A4,EPC1,SMARCD3,CABCOCO1,SNRPN,UNC80,USP33,DOP1A,SOX1,MYT1L,KDM3A,ZSWIM8,ERC1,IDI2-AS1,UNC5B,SPTB,CDK19,SPART,C11orf87,TAB2,MAPK8IP3,ELOVL4,CEP68,DIP2A,STAC2,ADHFE1,GSE1,KLHL7,SYT4,ANKRD12,KAZN,UNC5D,CNTN2,WSCD1,TCF4,TCF7,CLASP1,NAT16,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,FAM200B,PMS2CL,C18orf54,AP4E1,TGFBR3,AKTIP,CDH22,MTMR14,TIE1,TMEM9,TLR4,HEY2,RIMBP2,R3HDM1,SEZ6L,TPD52,CDK20,NPL,TPM3,CHST5,SYNPO2,METTL3,PRMT8,ELP5,TRIO,NEIL2,ZMYND8,DCBLD1,UBE3A,BCL2L13,VLDLR,WIPF1,XRCC4,ZNF19,TRIM9,ATP6V0E2,TMEM237,POLR3H,FTSJ1,SYNC,PRDM2,DNALI1,SLC38A1,GDPD5,LINC02210,MDH1B,ITM2C,FAM47E,WIPF2,FZD3,DOCK8,HNRNPA3,PHTF2,FAM219B,ZNF248,TIGD6,RNF170,VANGL2,IFT88" MicroRNA hsa-miR-1290:mirSVR_highEffct hsa-miR-1290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-146 7.48E-143 2.77E-145 2.55E-144 377 1581 "RALGAPA1,SERPINA3,NCKAP5,CSMD2,GALNT13,PNMA8B,PLEKHH1,DPY19L2P4,NLGN4X,PCDH19,NME5,OSBPL6,LRRC7,SPARCL1,ABCD2,UNC79,FAM135A,BEGAIN,AMPD3,AMPH,LRFN1,PHF12,APOC1,BCAS1,ARHGAP5,ASPH,BRINP2,DYNLL1,SLC4A4,ATP2B1,ZNF583,DPY19L3,TTLL9,BACH1,BCL7A,CFLAR,PROM1,ARHGEF7,JAZF1,MMD2,CACNA2D1,CABP7,THSD7A,KALRN,CAMK2A,CAMK2D,ISPD,CBLN1,C1orf52,CDC27,LGI1,MAGI1,SRSF11,CHN2,CHRNA4,JAM2,NRXN1,COG1,TPP1,FAM19A5,QKI,HECTD1,NIPBL,TMEM155,FHL5,AKAP7,IQCK,FAM149A,SLC4A7,RTTN,CP,AKAP12,CLIP3,TRIM69,ARHGEF10,CHD5,VCAN,PHF14,CFAP61,CTNND1,PUM1,FAM131B,CCDC144A,HDAC9,PHF19,PABPC5,DNAJC6,ZNF804A,C8orf34,ZBTB24,TIAM2,TMEM130,BLOC1S6,POM121,SMG7,KIF19,DLG2,DMD,CPEB2,PDCD6IP,FAM78B,MAMLD1,DYRK1A,WDPCP,EDNRB,KLHL5,EGFR,MBNL2,KMT5B,GOLGA7,EIF5,PLEKHA1,RGS17,C8orf37,EN2,GPHN,IGSF6,CDKL3,DNAJC27,RASL12,F3,F8,CLVS1,FABP7,ACSL4,TOMM40L,GORAB,SEC24B,FER,MED12L,FGF12,POLK,CAP2,PCYOX1,ANKFY1,TMEM107,CAMKK2,CELF1,PNMA2,NRG3,FYB1,PHYHIPL,STAG2,DKK3,GABRB1,ARPP21,C15orf41,DISC1,TUBGCP4,MSTN,ARFIP1,MALT1,PCDH11X,ZNF638,GNAL,FERMT2,ADGRA3,GPR34,RAPGEF4,GRIA2,GRIA4,ADAMTS8,GRM5,FAM19A2,RNF165,PSIP1,RNFT2,HAS2,MIER3,AGBL5,HTR2A,HTR5A,NKD1,RBPJ,TJAP1,LIX1,IL6R,LRRTM3,ITGAV,SLC35G1,KCNK2,KIF5C,KLC1,IPO5,STXBP5,PAXBP1,HECTD2,NCOA7,PIK3AP1,MAN2A2,MAOB,MAP2,MATN2,MATN3,TM6SF1,MDM4,MMP16,ZNF680,JAKMIP3,MSR1,ZNF92,CTNNA3,LAYN,BEX5,NDUFA5,RCOR2,OTOGL,NKX2-2,VWA2,CNOT4,NOVA1,SLC11A2,NUCB2,IGSF11,OGG1,LOC100128398,P2RY1,PAK3,CNTN3,ETFRF1,PDE3B,PDYN,BEST3,NLGN3,PIK3C2A,A2ML1,SNX10,RETREG1,GPSM2,HMGCLL1,MTRF1L,PMP2,TRHDE,LRP12,EPB41L4B,SLC36A4,PACSIN1,FAT3,SH3KBP1,POU3F2,PPP2R2C,RASGEF1B,MAPK9,HYDIN,SAMD9,VPS13C,WBP1L,SIDT1,SNRK,PTK2,TMEM260,OCIAD1,PTPRN2,ZNF615,PPP2R3C,TMEM255A,RALGDS,SH3TC2,OXR1,RADX,ZDHHC14,DPF2,ERI2,RFX4,TMLHE,KLHDC8A,GSTCD,ROBO1,CCDC102B,NEK11,RPL15,UEVLD,FBXW7,RPL38,ADAL,ACER3,LGR4,PTGR2,RTN1,NCBP3,AP1AR,RMI1,SCN3A,SCP2,TRA2B,NLGN4Y,FNDC3A,FHOD3,CNKSR2,PREX2,PPP4R3A,WDR47,SEPHS1,CCDC88A,BTBD7,ATF7IP,ZNF667,SMARCE1,RIMS1,MBD5,KIF13A,SNRPN,TMCC1,TRERF1,SOX2,SP2,ENKUR,NPAS3,STAU1,TTBK2,NECAB1,JMJD6,PRRC2C,SYN2,C12orf76,ANKRD12,DDHD2,UNC5D,AGTPBP1,FBXW11,ANO4,VWC2,SIN3B,SATB2,ZFP90,CRTC1,GPR161,HHIP,GZF1,C5orf64,CDK20,TPM4,WBP2,PRMT8,SMUG1,TRO,CLHC1,CADM1,RPL7L1,FAM155A,DNAJC12,SLAIN1,PITPNB,BCL2L13,BEST1,VSNL1,WIPF1,ZNF781,ZNF711,ZNF32,TRIM9,FMN2,ZNF74,PLPP4,CELF4,REEP1,FSTL5,EML6,ZNF189,EMSY,CADM2,PRDM2,PRTFDC1,STMN4,ADAMTS9,PCDH15,KCNAB1,MVB12B,PDSS2,RGS7BP,FZD3,MARCH8,KAT6A,HNRNPA3,NLRP3,FXR1,FRMD6" MicroRNA hsa-miR-3155:mirSVR_lowEffct hsa-miR-3155:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.79E-146 1.01E-142 3.71E-145 3.42E-144 424 1988 "ABCF1,ABR,ACLY,SYS1,KDM5D,ARID1A,CCDC85A,ADD1,ADD2,ADD3,AXIN2,GRAMD1B,ADORA1,KIAA1211,BEND6,ZNF608,OSBPL1A,OSBPL8,ALCAM,SRPX,FAM135A,SYT13,MRTFA,ZNF687,AMPD2,AMPD3,ZFAT,CNTNAP1,UPRT,BCAS1,TNRC6C,PPFIA3,CPNE5,LGR5,SHROOM2,SPTBN4,CADPS,CCAR2,ATP1A2,ATP1B3,STX16,SLC2A11,RNF182,CADM3,ADAM23,SNAI3-AS1,RGS9,BCL2L2,NRP2,CFLAR,KSR1,CDK5R1,SYNJ2,ARHGEF7,NAE1,BTK,C5,GPC2,WASF1,CACNA1B,CACNA1D,CALM1,KALRN,CAMK2B,SPAG9,MAP7,CCKBR,KRIT1,METTL6,INA,CD86,MYOM2,CDC25B,ZBED1,CDH8,TIGD7,CFL2,RCBTB2,CHGA,PLEKHB1,NDST3,RAB28,CLCN3,CLCN4,NMT2,TJP2,FADS2,IGLON5,CNTFR,IQCK,SLC25A27,COL11A2,SLC4A8,BAG4,MYRIP,IGDCC3,CHD1L,AKAP12,HINFP,CSF1R,SEC24C,SUSD5,ATRNL1,PLCH2,CST3,PPP1R16B,CMTM5,CFAP61,ECE2,NOS1AP,ARHGAP32,GAPVD1,LIN54,MAML1,PHYHIP,IP6K1,PABPC5,GIT2,SIRPA,PITPNC1,ZEB2,HEPH,COPS7A,C2CD2L,TMEM130,BLOC1S6,SV2A,SGSM2,WDR20,DLG2,EXOG,HS3ST4,HS3ST2,DNAH9,SLC29A4,SHANK1,DPP6,PDCD6IP,DTNA,FAM135B,EDN3,PHC2,FCF1,CNNM1,RBM12,FAM13A,PHF20L1,EGR3,GOLGA7,TENM1,TNK2,MRNIP,BSCL2,C3orf18,ENO2,EPB41L2,COQ7,ENPP6,ANKRD13B,MRPL10,TLR7,HSPA12B,NRN1,FAM198B,TBC1D16,ATP8A1,ZNF589,GTF2IRD2,SCARA3,UBE2E3,AGAP2,SEMA4D,SORBS1,DACH2,TBR1,MEGF10,GALNT15,ARPP21,ZNF234,DISC1,INPP5K,GCNT2,ARFIP1,GDF9,SESN1,GFAP,GFER,GHR,KIRREL3,TXNL4A,MSL3,DCLK2,GPD2,MCHR1,TMEM121B,RAPGEF4,GRB10,PLPP7,ADAMTS13,GRIN2C,PRDM5,SOX21,GUCY1B1,TOX2,NXPH3,MAN1B1,LINC01102,HSD17B1,MSL1,GAREM2,ZIC5,TJAP1,INPP5B,KCNMA1,GATD1,KHK,KIF5A,A1BG-AS1,LAMP2,STMN1,NCOA7,LOC100128239,MAP4,MARK1,MAT2A,SYT9,LDLRAD3,MDM4,MEIS1,POC1B,AFDN,MMP16,MOG,ERICH3,DBNL,SAMD5,RSPO2,MYCN,MYH7,MYO7A,HNRNPM,NEUROD1,NF1,NOVA1,NUCB1,OGG1,P2RX7,P2RY1,PAK3,PALM,PCSK5,PDGFRA,PFKFB3,HERC2P3,SEMA5B,CAMKV,TMIE,PIK3CD,CCSER2,ZFYVE21,ANKRD16,PMP22,PRRX1,SDK2,SEPT4,NXPH1,FSD1,PPP1R1A,PTPA,NKAIN4,CEP41,EPDR1,HYDIN,GDPD1,WBP1L,SIDT1,MDGA2,ANKHD1,PTPRH,PEX5,MARCH1,ACSS3,RAD17,CCDC40,RAD51D,SUSD4,NWD1,RAP1GDS1,DBX2,SLC6A15,ZYG11B,RET,PRRT2,ERI2,RFX3,RIT2,RIC8B,C12orf49,CYB561D1,KIRREL1,CCDC102B,RPE65,KIAA0895L,ADAL,MAP6D1,ATAT1,YJEFN3,KCNIP2,DGLUCY,SARS,SEMA6D,SCN3A,LRRTM4,LINC00461,FNIP1,ASIC4,CASC3,FOXRED1,ITSN1,ASAP3,SHC4,CHD9,FBXO11,FNDC3A,ST6GAL1,SLITRK3,BCAN,NUBPL,RAB3GAP1,SLC8A3,ARHGEF40,SLC9A5,SLC11A1,ELMO2,ATF7IP,ABTB1,SNCB,MAPKBP1,UNC80,USP33,PDZD2,MYT1L,TSNAXIP1,SPP1,DBNDD2,NFASC,LHPP,TROVE2,POGZ,ITPRID2,ZC4H2,ZSCAN29,NEK4,STXBP1,AJAP1,SUPT5H,PRRC2C,ZFR2,VAMP1,ARHGEF9,SYPL1,COBL,WWC1,MGRN1,ANO4,TCF7,TRIM2,AZIN2,SYNE1,NAT16,SLC19A3,HIF3A,RNF216P1,TF,DICER1-AS1,CDH22,ARL10,THRA,TIMP4,ACTR6,TMOD1,TNR,C9orf85,SMUG1,TRPS1,ZMYND8,TTTY15,ZKSCAN5,RPL7L1,UBE2H,LINC00689,PLEKHH2,MEAF6,VLDLR,BEST1,WIPF1,LAT2,NSD2,GUSBP1,ZIC1,PLPP4,GPR158-AS1,NDRG4,SLC26A10,TMEM237,ZNF177,POLR3H,ZNF213,ZXDA,PRDM2,CSDE1,PRDM10,RNF103,HPS4,EPM2A,GOPC,KAT6A,HNRNPA3,FBXO36,CAMK1G,NUP214,TRAM2-AS1,SSPN,PRRT4" MicroRNA hsa-miR-592:mirSVR_lowEffct hsa-miR-592:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-146 1.02E-142 3.74E-145 3.45E-144 382 1624 "KCNH8,ASIC2,GPRIN1,ADCY2,CCDC85A,GALNT13,AXIN2,KIAA1211,PTCHD1,SLC24A4,PCDH19,HACE1,SEMA6A,SRPX,CEP126,BIN1,CNTNAP1,APAF1,DGKD,AQP6,SPTBN4,ARHGAP5,STK33,DNAH17,ASPH,PCDHGB4,ATP2B3,RNF182,MYOM1,LINC00847,BCL2L2,MIR9-3HG,BMPR1B,CASTOR3,NIPA1,CA12,CACNB2,CACNB4,DIRAS1,CAMK2D,CANX,VXN,RHBDL1,PRC1,SEPT7,CDH18,CCPG1,SRSF11,PLEKHB1,KMT2C,CLCN4,COG1,DGCR9,QKI,MAP4K4,AKAP5,RCHY1,TOGARAM2,MFSD4A,SLC35F1,CLOCK,CREB5,AKAP12,SNCAIP,CSF1,CSF2RA,SEC24C,OSBPL3,ATRNL1,PDE4DIP,KIAA0040,PHF14,PLCXD3,PNPLA8,RIMS2,USP6NL,KIAA0408,EARS2,AIF1L,YTHDC1,HP1BP3,MAGI2,NTM,KBTBD11,DLG2,HS3ST4,USP3,NR1D2,CDON,DNM2,DRD1,DTNA,DNAJB6,DNM1L,FAM135B,EDNRA,FCF1,TMTC1,YAF2,SH3GLB1,SUGP2,EGFR,ABI2,GOLGA7,TENM1,CALCRL,EN2,RCAN2,STX2,ZNF549,DNAJC27,KATNAL1,NRN1,TAOK3,PRKAG2,FHL1,SCARA3,MEX3B,PCYOX1,SYNCRIP,AGAP3,FOXO3,EVL,FLT1,ANKFY1,PSD2,C2orf88,WDR83,TACC2,NPTN,NSG2,KBTBD12,MSANTD4,TVP23A,STAG2,MEGF10,GABBR1,GABRA1,GABRG1,BRPF3,ZMYND11,IP6K3,NCKAP1,ZNF559,DISC1,CPLX2,GATM,TUBGCP4,SULT1C4,PCDH17,BRD8,ZNF276,COPS8,PCDH11X,ZNF638,MAP7D2,GPT2,WDFY3-AS2,LILRB4,CNDP1,STON1,CECR2,GRIA4,GRIK1,ADAMTS13,GRM2,LINC00839,SOX21,ADAMTS6,HAS2,UBE2QL1,BACH2,HLF,TLX1,ZDHHC15,NEGR1,CPT1C,IDH3A,FAM95B1,LINC00667,MYLK2,IGF1,C5orf24,RBPJ,IL11RA,BRINP3,KCNA6,KCND2,KCNH2,KIF5A,KLRC3,KTN1,VWA5A,NCOA7,MAN2A2,MAP6,LYPLAL1,MBD1,MBP,CHIC1,TM6SF1,MEIS1,MEIS2,KITLG,MOBP,CCDC80,MTTP,MTR,MXI1,NCAM1,NEUROD2,NFIA,NFYA,LRIT2,SLC11A2,IGSF11,OPA1,OPHN1,OXTR,ZDHHC22,SNTG1,PCDHGC3,PCSK5,PDCD2,PDE3A,OLA1,ZDHHC8,PIK3C2A,MTRF1L,C11orf49,LRP12,EXOSC10,FAT3,POU3F2,TATDN3,PKIA,PRKCZ,MAPK10,PROX1,BCAS3,WBP1L,SNRK,BDNF-AS,PTPRN2,FAM120C,PEX2,PID1,RBBP6,KHDRBS2,ZDHHC14,ERI2,GTDC1,RGS4,RIC8B,RNASEL,RPRD1A,RAVER2,CCDC102B,FBXW7,BAALC,YJEFN3,STX1B,ATXN7,SOX6,STUM,ASRGL1,SCG5,FERMT1,SHC4,CHD9,R3HDM2,ANKRD6,NUBPL,SLA,SLC1A7,PPP4R3A,BTBD3,FAM214B,LRRC55,SEPHS1,SLC20A2,SLC22A4,SLIT1,CDK5RAP2,SNRPN,TMCC1,UNC80,DOP1A,PDZD2,KIF21B,NMNAT2,PEG10,ZC3H13,ARHGAP26,TSPYL2,TAB2,ATP10B,CLASP2,ITPRID2,LARP4,NKAIN2,LRRC4,STAU1,CEP68,STXBP1,SYT11,SUPT5H,PRRC2C,SYT1,COBL,CAMSAP2,FAM208A,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,OBSL1,PCDHB3,NSD1,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,DICER1-AS1,CRB1,GPR161,HEY2,TMOD1,TMPO,TPD52,ZNF346,SYNPO2,FNDC5,TTTY15,TMEFF2,LINC00689,FLRT2,BCL2L13,BEST1,RICTOR,KCNK12,XRCC4,MICU3,MKRN3,TCEAL7,REEP1,TMEM237,POLR3H,SH3GLB2,PRDM2,CSDE1,GDPD5,TMEM178A,PPP1R3F,SNX27,AMN1,DOCK8,HNRNPA3,JMJD1C,ZNF248,RNF170,FXR1,SOCS4,ST8SIA2,CPNE4" MicroRNA hsa-miR-1913:mirSVR_lowEffct hsa-miR-1913:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.25E-146 1.26E-142 4.62E-145 4.26E-144 395 1735 "TTYH1,ABCF1,ABR,ASIC1,RBM10,CSMD2,NDRG2,ADCY2,ADCY6,SORCS1,ERMN,FZD9,ADORA1,ADRA1B,AP1B1,SNX32,OSBPL1A,C1QTNF1,ADGRF5,ALAD,SEMA6A,CARNS1,FAM135A,KIF6,AMT,FGD2,MYH7B,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,KCNAB2,APBB2,DGKZ,GPAM,MADD,ARNTL,CDK13,CHID1,CCDC181,ZNF583,SLC2A11,RNF182,CADM3,NOL4,TTLL9,RGS11,BCL2L2,CFLAR,CACNA1I,KALRN,NGB,ARHGEF25,LDB2,USP6,CD86,CDC25B,IGFN1,COPB2,CBARP,CHGA,CHGB,ASIC3,PLEKHB1,KMT2C,FBXO7,TJP2,DNAJB5,IGLON5,ARHGEF6,SMARCAL1,MFSD4A,CHD1L,SEC31B,SH2B1,SNCAIP,FEZ1,MICAL2,PLCH2,SLITRK5,SDC3,APPL1,CFAP61,GPSM1,RUBCN,ECE2,KATNAL2,PHF19,ZFYVE16,EARS2,ZNF337,PHYHIP,TOMM20,ARMCX4,TIAM2,MFAP3L,COPS7A,C2CD2L,POM121,G3BP2,CHRDL1,DMD,DPYSL2,TOM1,DNM1L,AASDH,EDN1,EDNRB,PHC2,CNNM1,KLHL5,SIDT2,EFNA3,CELSR3,FAM13A,TMEM132E,ING4,TNK2,C3orf18,EML1,CALCRL,LRRC23,RASGRP2,SRRM1,EFS,SPEG,MRPL37,MRVI1,CLVS1,FABP7,TMEM132C,PTK2B,DLC1,FGF11,SPSB4,BAIAP2,CAP2,FOXF2,AGAP3,PSD2,POMT1,ATP6V1H,ZNF605,KHDRBS3,CELF1,GPR153,DLL3,KBTBD12,HHIPL1,TMEM151A,AP4B1,FYB1,DKK3,GAA,BRPF3,B4GALNT1,ZNF234,GHDC,DISC1,SEPT9,CPLX2,ALDH1L1,TUBA8,GFAP,GFER,USP19,KIRREL3,BRD8,RND1,PCDH11X,GPD1,CCDC184,TMEM121B,GRIA1,DIDO1,C1QL4,ADAMTS13,GRIK5,GRIN1,GRIN2C,GSN,CLASRP,PTPN5,KAT7,GPR45,PTGDR2,NCKAP1L,KLF12,OPALIN,HTR5A,ATCAY,ICA1,IRF8,MSL1,MYLK2,KNDC1,USP54,IL6R,TMEM240,INPP5B,ITGA7,CDH20,KCNA6,KCND1,KCNH2,KCNJ10,KCNJ11,KCNMA1,STXBP5,SFXN5,MAG,MAP6,MATN2,MEIS1,MEIS2,MGAT3,SCAMP5,AFDN,XRRA1,MOBP,GIT1,JAKMIP3,TMEM249,MDGA1,FXYD6,NCAM1,RCOR2,NELL2,NF1,CNOT4,NTRK3,NUMA1,GPR88,OGDH,ZDHHC22,PDE3B,PDE4A,PDE4B,BEST3,OLA1,SNX10,XRN1,TMEM38A,PLCB2,ST8SIA5,C11orf49,STRN3,RC3H2,ING3,RETREG2,TNPO2,POU3F2,POU6F1,MED1,TATDN3,PPP3CB,KANSL1,HYDIN,WBP1L,TMEM104,PTAFR,PTN,PTPRB,CASTOR1,PTPRG,NKAIN1,RAB5B,USP47,RALGDS,SLC25A41,RASGRF1,FEZF2,GAL3ST4,TRIM68,RGS3,KIF7,RNF220,PBRM1,LGI2,MYH14,EXD2,KIRREL1,CCDC102B,SNX22,EPHA10,KIAA0895L,ATP8B4,SGSM1,STK32B,PTGR2,MEG3,ABCA11P,ATAT1,KCNIP2,SATB1,SBF1,SCP2,HES6,SEC14L1,GALNT10,SFPQ,ITSN1,PPP1R9A,FERMT1,SHC4,CHD9,NLGN1,ST3GAL3,PEX26,SLC6A7,SLC6A8,SLC6A9,SLC6A11,SLC11A1,SLC12A4,CDK5RAP2,INTS9,MAPKBP1,SNRPN,UNC80,USP33,FAM219A,WDTC1,TRERF1,KIF21B,BDP1,TSNAXIP1,ZSWIM8,NMNAT2,ENKUR,KDM4C,ERC1,SPTB,NFASC,ATP10B,LRRC4,NCDN,AJAP1,GSE1,SYT11,SUPT5H,ZFR2,VAMP1,NUDT10,DNAJC9,TMEM150C,ROBO3,CAMTA1,EXOC7,WWC1,ANO4,TBX15,NEU4,CUX2,WDR7,SYNE1,NAT16,TNS2,FRYL,HIF3A,RNF216P1,PMS2CL,LEFTY2,FBXL16,TJP1,LRRC8A,BEX4,TNFRSF1B,LILRA4,TPM1,NPL,ZNF346,PRMT8,TRH,PPIL6,FNDC5,TUB,ZKSCAN5,RPL7L1,UBTF,PLEKHH2,LMF1,KLC2,RICTOR,LGI4,ELFN1,ATP6V0E2,SLC26A10,WNK1,MAP3K12,XKR7,SEMA3B,SLC17A7,PPP1R3F,PCBP4,ADAMTSL3,FAM181A" MicroRNA hsa-miR-4298:mirSVR_lowEffct hsa-miR-4298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.29E-146 1.29E-142 4.70E-145 4.33E-144 389 1684 "ACADM,EMILIN3,KDM5D,ARID1A,SLC25A25,NDRG2,FMNL2,ADARB2,TMEM132B,PNMA8B,PTCHD1,ADRA1D,FAHD2CP,KIDINS220,NLGN4X,C1QTNF3,ALCAM,PCDH10,KCNT1,AMPD2,CDC42BPA,EP400,CCDC146,LCORL,PPFIA4,PHF12,PPFIA1,API5,SHTN1,LGR5,CDK10,SEMA4G,IGDCC4,ARHGDIG,ARRB2,ASPH,SLC4A4,ALDH7A1,ATP6V0A1,KIF1A,ADAM23,MPDZ,SEC11C,BID,CFLAR,SYNJ2,AP1M1,NIPA1,GPC2,CDK5R2,CACNA1E,CACNB2,CACNB4,CALM1,CAMK2B,TRIM41,CARS,SPAG9,USP6,P2RX6,AP4M1,CDC25B,CDC42,LGI1,L3MBTL4,MAGI1,CCPG1,NOG,ADGRG1,PLEKHB1,DLGAP3,STOML1,MAP4K4,TMEM155,FHL5,IQCK,AKAP6,TBPL1,SMARCAL1,MFSD4A,NECTIN3,SLC35F1,CRY2,SNCAIP,CSF2RA,OSBPL3,PLCH2,VAC14-AS1,PDE4DIP,ERC2,UBXN2A,EDRF1,CX3CR1,KIAA0408,BOC,DCAF8,IST1,GIT2,ARMCX4,ELMSAN1,RUSC2,C2CD2L,TMEM130,BLOC1S6,POM121,RABGAP1L,DLG2,EXOG,DMD,SLC29A4,CDON,DMTF1,DPH1,PDCD6IP,DUSP9,PHC2,SIDT2,PHF20L1,SUGP2,TNK2,CALCRL,ENO2,EPB41,EPB41L1,CEP85L,ZNF549,MRPL37,EZH1,ZNF585B,TBC1D16,TAOK3,DLC1,CHST15,FKTN,KAT8,MED12L,KIAA1109,IP6K2,PSD2,C2orf88,EFCAB2,SORBS1,UFM1,FAM49B,ATP2C1,ERGIC3,CELF1,CGREF1,TMEM151A,NRG3,FYN,STAG2,GABBR1,GABRA2,GABRB3,TRAF3IP2,GAD2,HBS1L,GCK,ALDH1L1,GCNT2,CYP46A1,GFAP,GFRA1,PPARGC1A,GK,ZNF276,COPS8,PCDH11X,GPT2,ADGRA3,GPER1,RFFL,ADAMTS13,CACFD1,GRM5,GRM7,SLC2A6,ATOH8,IRAK3,ATXN2L,SHISA6,IRF8,MSL1,LINC00667,C5orf24,LRRCC1,DISP2,IGSF1,ITGA7,METTL21A,KCNJ3,KCNK3,KCNMA1,CREG2,TTYH2,PAXBP1,HECTD2,MAN2A2,MAP4,SYT9,ADAM11,MDM4,MEIS1,MEST,KCTD6,SCAMP5,AFF1,MN1,DBNL,PTOV1,RSPO2,ZNF862,FXYD6,NBL1,NHLH1,NNAT,NOVA2,SLC11A2,NUCB1,NUMA1,OGG1,OLR1,OPHN1,P2RX7,PAK3,PC,PCSK5,CDK18,PDE4A,ENPP2,FAM98B,GDAP1L1,GPSM2,NLE1,FTO,PLIN1,HMGCLL1,PURG,PNMA3,EXOSC10,SCHIP1,PRRX1,RETREG2,SEPT4,FA2H,FAT3,PPP1R1A,PCDHB17P,PPP2R2C,VSTM2L,PRKCG,GRAMD1C,MASP1,ANKHD1,PTPRE,CASTOR1,PEX2,TMEM231,CEP97,CCDC40,ATG16L1,IQSEC3,NWD1,RASGRF2,SLC6A15,RFX2,PRIMA1,SLC25A36,ARMC5,YY1AP1,RPE,FBXW7,BAALC,KIAA0895L,MCMBP,ADAL,LGR4,ST6GALNAC6,WLS,YJEFN3,KCNIP2,ZNF354C,DGLUCY,ATXN7,HOGA1,SCN4B,PRCD,SCP2,ASIC4,TRIM46,SFPQ,MYO18A,SHC4,FNDC3A,PAAF1,ABLIM3,ZNF365,SLC2A5,PEX26,LIMS2,NAPB,TMEM132D,SCMH1,NAXD,OGDHL,SORCS3,SMARCD3,RCOR3,CABCOCO1,PDZD2,BDP1,SOX10,SP2,ZSWIM8,NPAS3,ATP10B,CAMTA2,SSTR1,ZC4H2,LARP4,STAC2,ADHFE1,NSFL1C,FAM168A,SYT11,MLC1,COBL,SLC37A2,TAC1,TAC3,PDLIM2,KLHL4,TBX15,WSCD1,SATB2,TPCN2,RPGRIP1L,TCF12,WDR7,NAT16,PHF24,PUM2,USP32P1,AHCYL2,CRB1,C18orf54,TIMP4,LRRC8A,FAM124A,TNNT1,TNS1,TPM1,WBP2,SMUG1,ELP5,HEPACAM,UBE3A,PLPPR2,VLDLR,BEST1,P2RY12,RICTOR,GUSBP1,ZIC3,NDRG4,LYPD6,TCEAL7,ZNF189,SPIRE1,SYNC,EMSY,PRDM2,PRTFDC1,DNALI1,GDPD5,STOX2,SCG2,FIP1L1,ITM2C,SLC17A6,GOPC,FBXO36,NUP214,JMJD1C,ZNF248,VANGL2,FRMD6,IFT88" MicroRNA hsa-miR-593*:mirSVR_lowEffct hsa-miR-593*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-146 1.33E-142 4.84E-145 4.46E-144 398 1761 "ABCF1,ABR,ASPHD1,ASIC2,NCKAP5,KDM5D,XKR4,NDRG2,ADD1,AP2A2,FAM135A,ZNF687,CDC42BPA,ANK3,EP400,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,FAM131A,SHTN1,CDC14B,SLC7A14,TMEFF1,ZFYVE28,ARHGDIG,PDE8B,STK33,ASPH,DACT3,PCDHGB4,ATP1A2,STX16,ATP2A2,SLC2A11,ADAM23,TTLL9,ADAM15,BCL2L2,KSR1,CACNA1G,LDLRAD4,BTRC,CA4,PTBP2,NGB,SPAG9,P2RX6,CD86,TMEM257,NEURL1,CDH8,CACNA2D2,GPR37L1,PLEKHB1,CNOT8,JAM2,TAOK2,LSMEM2,RAB33A,NRXN3,TPP1,CLTC,ARHGEF6,ANKRD35,SLC4A8,SMARCAL1,CHD1L,CREM,HINFP,SNCAIP,LRIG1,FEZ1,MICAL2,OSBPL3,PLCH2,RIMS4,ERC2,APPL1,CFAP61,EDRF1,HDAC9,MYADM,ARHGAP32,GAPVD1,TCAF1,DCAF8,FRMPD4,PHYHIP,DAPK1,IP6K1,ARMCX4,JAKMIP2,CNIH3,POM121,RHOBTB1,SV2A,FAM107B,TRAPPC9,DYNC1I1,DPP6,GNE,ARRDC4,KRBA2,GOLT1B,SEZ6L2,FEM1B,SIDT2,CELSR3,KMT5B,ABI2,TMEM132E,GOLGA7,KCTD3,EIF4G2,SORBS3,EIF5,IRAK4,TUBD1,COQ7,EPHB1,ANKRD13B,ERBB2,APC2,ETV1,REEP2,F8,TUBB4A,SCML2,ZSCAN30,ZNF589,MED12L,FGFR1,MAD2L2,POLK,SUCO,MEX3B,FOXG1,FOXF2,SYNCRIP,NOP56,CELF1,ST6GALNAC3,DLL3,PNMA2,HHIPL1,DKK3,GABRA3,GAD2,BRPF3,JPH4,ARPP21,ATP8A2,WASF3,ALDH1L1,CRCP,TNRC6A,MSL3,PCDH11X,ADGRA3,PRUNE2,CCDC184,NUDT21,GPR37,TMEM121B,RAPGEF1,GRIA1,GRIK5,GRM7,ZNF496,RNF165,KAT7,MAP4K5,TMEM179,RASSF8,TOX2,PADI2,FRMD5,MAN1B1,HRH3,ARHGAP19,ELOVL5,HNMT,LRRC75A,LINC00667,GAREM2,LRRCC1,IL11RA,ITGA7,KCNA6,KCNJ9,KIF5C,LINC00634,A1BG-AS1,LAMA2,STMN1,SMAD9,MAN2A2,ZFYVE27,MBD1,KITLG,MITF,COL28A1,COMMD5,MYO9A,RTL5,PABPC1L2A,NAP1L3,NEFM,NFE2L2,NFYA,VWA2,NTRK2,OCRL,OPCML,OPHN1,OPRL1,ZDHHC22,SNTG1,PBX1,PCDHGC3,CDK18,PDE1B,ENPP2,PDPK1,GNG2,PFKFB4,SSH1,TMIE,ST8SIA5,PLP1,PURG,SCHIP1,ING3,PRKAB2,MAPK9,SLC22A23,LRRC49,PIGG,CNTLN,UHRF1BP1,PTHLH,ELOVL2,SPDL1,PTPRO,QDPR,RAD51D,RALGDS,NWD1,HKR1,ZYG11B,RGS3,ARHGEF10L,ZFHX4,ALG9,CYB561D1,ROBO1,SNX22,NEK11,ACER3,ATAT1,FAM182A,FAM192A,AP1AR,DGLUCY,LINC00461,SCP2,PEAR1,CASC3,GALNT10,MRAS,AMBRA1,CTXN2,DZIP1,RPH3A,SLC2A5,PEX26,SMTN,SEPHS1,RAB3GAP1,ARHGEF40,LGI3,SLC22A4,SLIT1,ZKSCAN3,INTS9,IFT122,INAVA,RIMS1,FAIM2,SNRPN,TMCC1,FAM126B,ZHX3,KDM4C,ERC1,IDI2-AS1,NFASC,SRPK2,PBLD,SMOC1,SSPO,NCDN,ZSCAN29,ELOVL4,STAC2,KANK1,SYT11,MLC1,FGD4,JMJD6,ZC3H4,PRRC2C,VAMP1,RHBDL3,NUDT10,COBL,DDHD2,PDLIM2,ALG1,CNTN2,TCF4,SIN3B,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,NAT16,PCDHGA1,DOCK9,SLC19A3,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,PMS2CL,C18orf54,KAT6B,WBP2,ZNF346,SYNPO2,SMUG1,TRH,TRO,FNDC5,RUSC1,TSN,CLHC1,SLAIN1,OSBP2,PLPPR2,VAV1,WRN,NPDC1,GUSBP1,SLC13A3,ZNF28,TRIM9,ATP6V0E2,ZNF70,PLPP4,NDRG4,SLC26A10,ZBTB16,ZNF154,ZNF213,MEIS3,SLC30A3,RGMA,CSDE1,ADAMTS9,HPS4,VPS35L,MDH1B,PCDH15,WIPF2,UBE3B,CASC15,NUP214,FAM219B,TTC7A,NETO1,SENP7" MicroRNA hsa-miR-493:mirSVR_lowEffct hsa-miR-493:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.71E-146 1.52E-142 5.51E-145 5.08E-144 385 1651 "SERPINA3,SDE2,SYS1,KDM5D,XKR4,ADAR,GALNT16,CCDC85A,ADD2,ADD3,BRAP,PLEKHH1,ADORA1,PWWP2A,ADRB2,NLGN4X,AK2,ALAD,GOLGA7B,AMPD3,OGT,CCDC146,MAP4K3,ANXA7,APC,LGR5,MIER1,CDK10,PDE8B,CHRD,NCOA1,ASTN1,DDX3Y,SLC2A11,TTLL9,BACH1,MPDZ,BCL2L2,DCAF5,BLM,CFLAR,BMP7,SYNJ2,JAZF1,CACNA1E,LURAP1,CALB2,THSD7A,CALM1,PTBP2,TRIM41,VSTM2A,CH25H,NFS1,P2RX6,CBFA2T2,TMEM257,CD38,CDC42,CDR1,TIGD7,CCPG1,IGFN1,CHN2,CASC2,MS4A7,KIAA1549L,COG1,TPP1,TJP2,SULT4A1,IGLON5,ARMC8,COL9A2,COL9A3,ABI3BP,COX4I1,MFSD4A,SLC35F1,RBM39,ANKRD44,NCOR1,NCOR2,CLIP3,ABCG1,CSF1R,SOCS5,PDE4DIP,CCDC144A,BOC,DOCK4,FRMPD4,PHF19,EARS2,ZNF337,LONRF1,KIAA0586,DGKG,DAPK1,DNAL1,PITPNC1,JAKMIP2,CNIH3,COPS7A,KIAA0319,SPOCK3,SRGAP3,NTM,DLG3,DLX1,USP3,DOCK2,DMTF1,SLC25A18,ACOT8,GNE,ECM2,DYRK1A,E2F5,EDN1,FAM13A,COPS4,ELAVL4,ELN,C3orf18,TMEM35A,RASGRP2,ENPP6,EPS8,IGSF6,RTN3,CLVS1,FAM198B,SH3YL1,CACNG2,TUBB4A,FCGR1A,FCGRT,TESK2,FER,OLFM1,POLK,SUCO,SYNCRIP,SLC37A3,EFCAB2,WDR83,PDLIM5,STAMBP,NPTN,CAMKK2,CELF1,PNMA2,MPP6,BRSK1,FYB1,GABRA2,HRASLS5,CHL1,GABRB3,ILDR2,AHCYL1,ZMYND11,ARPP21,IP6K3,ACSS1,DNER,GDF9,GPR162,USP19,STARD3,OS9,GNG4,PRUNE2,FUT10,PRLHR,EML4,RAPGEF4,RAPGEF1,GRIA1,GRM3,GRM7,ZNF496,RNF165,TMEM25,ZBTB49,WIF1,PADI2,ZHX1,PTGDR2,ATXN2L,HMGCR,CPT1C,DHX35,LINC00667,IGF1,ZIC5,KIAA1755,PLD5,SCIN,ITPKA,KCNA6,KCNC1,KCND2,KCNJ10,STMN1,LMO2,VWA5A,PACRG,ZNF667-AS1,MAP2,MAP4,MARK1,LDLRAD3,WDR49,SAMD5,MSI1,BCO1,MSR1,RSPO2,NAP1L2,FXYD6,NCAM1,NCAM2,NDUFA5,NF1,LRIT2,SMIM11A,NUCB1,NUCB2,OPA1,OPHN1,ZNF713,GPR137C,CNTN3,PAX6,DPY19L2P2,ETFRF1,PCDH9,PDE3B,PDE4D,PFKFB3,TMEM38A,KCTD15,GPSM2,FTO,MTRF1L,MAPKAP1,SCHIP1,ING3,EPB41L4B,PPP2R2C,PPP2R5C,PRKACB,SLC26A11,RELN,CNNM2,BCAS3,SYTL2,GDPD2,SNRK,PSMD13,PIGG,MTMR10,ZSCAN2,FAM66C,SH3TC2,ATG16L1,RASGRF2,BSDC1,MSANTD2,ERI2,FIGN,RGS12,RIT2,TMLHE,EXD2,ALG9,CARF,ROBO2,SNX22,ARMH4,BAALC,SGSM1,PRR5L,FAM192A,SAFB,ASIC4,ELMOD1,IL17RB,SFPQ,MRAS,HSPA4L,ZFP30,FRMPD1,ARX,FERMT1,MYO18A,SHC4,FBXO11,FHOD3,NLGN1,ST3GAL3,DZIP1,PPP4R3A,RUFY2,SLC6A8,SLC8A1,CCDC88A,SCMH1,TTC17,KIF13A,TMCC1,UNC80,KDM4B,DOP1A,WDTC1,TRERF1,NMNAT2,EMC1,MCF2L2,RBM26,SRPK2,ATP10B,EPB41L3,SEPT3,FAM168A,FNDC9,C3orf70,SYT1,COBL,ROBO3,ANO4,VWA3A,EHBP1,ZFP90,FAM189A1,SIK3,TEK,PMS2CL,C18orf54,LEFTY2,TIAM1,KCTD2,R3HDM1,KAT6B,PIK3R5,TPM1,TPM2,FNDC5,ZKSCAN5,UBE3A,AMOT,LINC00689,UGT8,SLAIN1,USP1,BCL2L13,GUSBP1,LGI4,ZNF28,ZNF540,PLPP4,ZNF138,CELF4,AMZ1,TFIP11,ZFAND5,NT5M,DNALI1,CSDE1,STOX2,NAV2,FAM47E,WIPF2,SLC17A6,DOCK8,UBE3B,FAM219B,JMJD1C,TRAM2-AS1,RNF170,NETO2,SLC4A10,JPH3" MicroRNA hsa-miR-183:mirSVR_lowEffct hsa-miR-183:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.04E-146 1.71E-142 6.15E-145 5.67E-144 396 1745 "KCNH8,ASIC2,CLK4,CSMD2,KLHL32,PLEKHG5,TMCC3,GALNT13,AXIN2,SLC12A5,CDC7,PWWP2A,ADRA1D,BEND6,INTS2,HACE1,TAOK1,ALAD,ABCD2,MRTFA,ZFAT,LRCH2,CCDC146,USP28,PHF12,ANXA7,ALS2,PPFIA3,SHTN1,CDC14B,RGS20,CADPS,N4BP2L1,DPY19L3,ATP6V0A1,ADGRB3,RGS9,BCL2L2,NRP2,KSR1,BMPR1B,DST,SYNJ2,ARHGEF7,BTK,C5,CACNA1E,THSD7A,HAP1,PTBP2,TRIM41,CBR1,LDB2,CERS5,CBFA2T2,SCARB1,CD38,C1orf52,SEPT7,REPS2,LGI1,MAGI1,CACNA2D2,CFL2,SOCS6,MS4A7,NDST3,KMT2C,MYL6B,CLTA,SRP14-AS1,HECTD1,AKAP7,PCYT1B,ARMC8,AKAP6,IFFO1,AHCTF1,MYRIP,ZNF521,MFSD4A,CREM,CSNK1G3,IPCEF1,NCAN,GPSM1,ZSCAN23,FAM131B,NOS1AP,DOCK4,ARHGAP32,MAML1,IST1,BRINP1,GIT2,YTHDC1,DCTN1,FBXL5,COPS7A,MAGI2,KLHL3,SPOCK3,SV2A,HS3ST2,DNM2,DRP2,ARRDC4,DNM1L,E2F5,EDN1,HIPK3,TMTC1,SIDT2,SH3GLB1,CELSR3,EGFR,MBNL2,ABI2,GOLGA7,PLEKHA1,PCOLCE2,EML1,GPHN,EFS,ZNF549,ANKMY1,MRVI1,TAOK3,EFEMP1,FGFR1,POLK,FOXF2,PDLIM5,FAM49B,ARFGAP2,ATP6V1H,ZNF605,CGREF1,ST6GALNAC3,PNMA2,FYN,GABRB1,CAB39,GAD1,BRPF3,GAP43,SIGLEC8,ATP8A2,TUBGCP4,SULT1C4,FREM1,PPARGC1A,BRD8,TNRC6A,MSL3,MAP7D2,DCLK2,GNG4,GOLGB1,PRUNE2,LILRA1,CECR2,GRIA1,GRIA4,PLCD4,PLPP7,GRM7,TMEM25,BVES,LINC01551,ADAMTS6,MAP4K5,UBE2QL1,HPS5,PADI2,ZHX1,BACH2,HLF,ELOVL5,HMGB1,SYNPO,IGFBPL1,ZDHHC15,SHISA6,SMAP1,EID2B,SOWAHA,RBPJ,ITGAV,KCNMA1,KCNN2,KIF5C,STXBP5,LIFR,SFXN5,PAXBP1,SYTL4,VWA5A,ARHGAP12,PIK3AP1,MAN2A2,MARK1,MATN3,ADAM11,LDLRAD3,LRP1B,KITLG,MOBP,PTOV1,MXI1,MYO9A,NAP1L3,NCAM2,NOVA1,SLC11A2,NTRK2,NUMA1,IGSF11,OGDH,GLIPR1L2,PCDH8,PCDH9,PDCD2,PDE4D,PIRT,PFKP,HERC2P3,ZNF655,A2ML1,PLIN1,ANKRD16,PDZRN4,TRHDE,PSAT1,SCHIP1,MED1,CRLS1,PPP3CA,PRKAB2,CEP41,PRKCB,EPDR1,MAPK7,RELN,SLC22A23,MDGA2,PTCH1,BDNF-AS,PTK2,PTPRH,USP47,PLEKHB2,RALGDS,NWD1,ZNF493,MSANTD2,RDX,TRIM68,REV3L,GTDC1,FIGN,RGS3,ARHGEF10L,SLC25A36,PBRM1,GSTCD,MRAP2,RPE,RPL15,BAALC,ATP8B4,ACER3,ST6GALNAC6,RYR3,TRAPPC13,SAFB,SARS,SEMA6D,CSRNP3,LRFN5,SCN3A,SMPD3,SEC14L1,MRAS,SUPT20H,PPM1E,MYO18A,DOCK10,SHC4,HKDC1,FBXO11,FNDC3A,FHOD3,ST3GAL3,SEC31A,ZNF365,PPP4R3A,BTBD3,EPN2,RAB3GAP1,ZNF334,NAPB,SPHKAP,LGI3,SLC22A4,CPEB4,NAXD,ANKRD36,INAVA,SNCB,FAM126B,TRERF1,ZHX3,NMNAT2,ARHGAP26,KIF1B,EPB41L3,LRRC4,ZSCAN29,SEPT8,PHLDB1,GSE1,KLHL7,JMJD6,SYNE2,COBL,TAC1,DNMBP,AGTPBP1,TBCEL,ANO4,CUX2,PCDHB9,PCDHB3,SLC35G2,HIF3A,TEX15,SIK3,CYB561A3,ITGB3BP,ZNF106,AKTIP,ARL10,THRA,TIAM1,HEY1,TK2,BHLHB9,FAM124A,R3HDM1,CSMD1,C9orf85,PRMT8,PDSS1,AMACR,STXBP4,TRPS1,ZMYND8,TSN,TSC1,CLHC1,CADM1,AMOT,BCL2L13,PLPPR2,TBC1D15,SF1,ZNF711,ZNF45,LYPD6,REEP1,EML6,PCBP1-AS1,PLPPR5,SMARCAD1,INTS3,MFF,PRDM2,RGMA,EVI5,GDPD5,PRDM8,NAV3,SLC17A7,KCNAB1,SLC17A6,PARP11,UBE3B,CERS6,JMJD1C,MSRB3,SNX14,PIANP,IFT88,SLC4A10,GAN" MicroRNA hsa-miR-15b:mirSVR_highEffct hsa-miR-15b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.11E-146 1.75E-142 6.28E-145 5.78E-144 361 1454 "ABCF1,KCNH8,ACADM,NCKAP5,SYS1,CSMD2,CCDC85A,GALNT13,AXIN2,CDC7,ADRB2,AP2A1,AP2A2,DISP3,LRRC7,ALAD,SRPX,ARHGAP20,OGT,ANK2,CNTNAP1,GPAM,ALS2,BCAS1,PPFIA3,APP,LGR5,SHROOM2,CDC14B,CASK,STK33,ZBTB10,DDX3Y,TTLL9,MPDZ,BCL2L2,NRP2,CFLAR,CDK5R1,SYNJ1,FUBP1,SCAPER,MTMR3,BTRC,CA8,CACNA1B,CACNA1E,KALRN,VSTM2A,CAST,MAP7,RUNX1T1,ARHGEF1,CDC42,TIGD7,CHM,CHRNA4,PPT2,CLCN3,CLCN4,NRXN1,COG1,QKI,HECTD1,BTF3L4,SLC4A7,SLC4A8,TBPL1,MYRIP,MFSD4A,SEC31B,PREPL,CRYM,LRIG1,FEZ2,MICAL2,SOCS5,PDE4DIP,ERC2,CFAP61,USP6NL,CX3CR1,ARHGAP32,KATNAL2,RIPOR2,DCAF8,PHF19,KCTD8,IP6K1,ARMCX2,YTHDC1,JAKMIP2,C8orf34,PLEKHM1,FBXO25,SPOCK3,G3BP2,DLG2,USP3,DNAH9,DYNC1I1,CPEB2,DMTF1,DRD1,ACOT8,FAM78B,DYRK1A,DNM1L,GOLT1B,TSPAN5,ANKRD46,FCF1,CNNM1,SIDT2,RBM12,PHF20L1,MBNL2,ABI2,PLEKHA1,PAN3,EN2,RCAN2,GPHN,DENND4A,CEP85L,SPEG,CDHR1,RTN3,EYA1,NRN1,ACSL4,RACK1,FGFR1,PRKAG2,SUCO,MEX3B,RGPD5,SLC37A3,PDLIM5,CELF1,CSPG5,NSG1,OGA,ARPP21,ERAP1,DISC1,SESN1,USP19,PCDH17,GHR,INSM2,GNAS,FERMT2,GPD2,GRM7,RNF165,WIF1,RASSF8,ZHX1,FRMD3,HMGB1,OPALIN,HTR2A,MSL1,RBPJ,NIM1K,SCIN,ZNF678,INPP1,NME9,SLC35G1,KCNC2,KCND2,KCNJ11,KCNK1,KCNK2,KIF2A,KIF5A,KIF5C,LAMP2,ARHGAP12,MAP4,LYPLAL1,AQP11,MBD1,MBNL1,TM6SF1,LRP1B,MN1,MSR1,THYN1,MYBPC1,RTL5,PABPC1L2A,NAP1L2,NDP,SLC11A2,NTRK3,ODF2,OMG,GPR137C,CNTN3,ETFRF1,PCDH9,PCMT1,PDE1A,PDE3A,PDE3B,PDE4D,PDPK1,SLC10A4,BEST3,PIK3R1,JAKMIP1,PLP1,PSAT1,PRRX1,RETREG2,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,RASGEF1B,PRKCG,PKN2,GDPD1,MASP1,RELN,CNNM2,SYTL2,GDPD2,SNRK,CNTLN,PTCH1,PTHLH,STK32A,ZSCAN32,PTPRD,PEX5,PID1,TMEM255A,FAT4,RBBP6,ZDHHC14,RDX,RET,RFX4,RFX5,SEC61A2,SLC25A36,RIC8B,ZFHX4,CARF,GSTCD,TMEM100,RPL15,ARMH4,FBXW7,SYNDIG1,ABCA11P,KCNIP1,ZNF568,TMEM156,SALL1,MAPK12,SEMA6D,ATXN2,ATXN7,SCN2A,SCN3A,SCN8A,ELMOD1,SLC30A10,SELL,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,ST3GAL3,ANKRD6,FAM81A,BTBD3,ARHGEF40,KBTBD4,SLC20A2,SLC22A4,CPEB4,SLN,RCOR3,SNAP25,MBD5,SNRPN,UNC80,SON,MYT1L,UNC5B,ZC3H13,KIF1B,TSPYL2,RBM26,NPAS3,NFASC,ADHFE1,PHLDB1,ACSBG1,PRRC2C,SYNE2,VPS13A,C3orf70,SYPL1,SYT4,C12orf76,KAZN,WWC1,TBCEL,TCEA1,TPCN2,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,TGFBR3,ERCC6L2,HEY2,TMOD1,KAT6B,TP53BP2,NPL,TPM2,RUNDC3B,TRPC1,CADM1,AMOT,LGI4,ZNF708,TRIM9,EML6,ANKS1B,SLC30A4,PMEPA1,CSDE1,STOX2,TUBA1A,PCBP4,WNK3,PLSCR4,FZD3,ADAMTSL3,SNX14" MicroRNA hsa-miR-146a:mirSVR_lowEffct hsa-miR-146a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-146 1.80E-142 6.46E-145 5.95E-144 414 1902 "ACADM,EMILIN3,CSMD2,ARID1A,XKR4,FMNL2,ADCY2,CCDC85A,ADD1,RNF150,MTA3,AP2A2,ZNF608,GPR158,SNX32,CASKIN1,OSBPL1A,WDR35,OSBPL8,ZNF578,ABCD2,GPRASP2,SYT13,AMPD3,CDC42BPA,ANK2,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,ANXA7,DGKD,ALS2,USP37,SHTN1,PPP4R4,TMEM263,DNAH17,ASPH,PCDHGB4,ATM,ADAM23,ADAM15,LINC00847,BCHE,RGS9,BLM,DST,SYNJ1,OSGIN2,MMD2,CACNB4,CALB1,SLC25A14,PRC1,CD86,TMEM257,CDH8,DCLK1,CDH18,DLGAP1,UBE2L6,GPR37L1,CHRNB2,CLTA,CNTN1,FAM149A,AKAP5,RCHY1,ZFP28,CHD1L,SEC31B,CREM,RBM39,RNF14,ANKRD44,CRYM,CS,OSBPL3,ATRNL1,GALNT9,PNPLA8,GREB1,ARHGEF4,CFAP61,ZSCAN23,ECE2,ARHGAP32,GAPVD1,SNPH,RASSF2,IST1,GIT2,DNAL1,HEPH,CNIH3,FBXL5,KIAA0319,LYPD1,SGSM2,DLG2,DLX1,GRIN3A,DOCK2,DSCAM,HEYL,EBI3,MBNL2,EGR3,TMEM132E,AASS,TENM1,CALCRL,SEZ6,EPHA5,ANKRD13B,RABEPK,EPS8,NCALD,EFS,CDHR1,MRPL10,DUSP27,RCSD1,TLR7,KATNAL1,ADGRV1,MRVI1,FAM198B,DLC1,ST3GAL6,CHST15,ZSCAN30,FECH,FER,GTF2IRD2,OLFM1,CAMSAP1,PCYOX1,SYNCRIP,IQCG,FLT1,SMC2,ATP6V1H,ATP2C1,ZNF605,STAU2,PNMA2,NRG3,TVP23A,ZNF512,GABRG1,GAD1,GAD2,HBS1L,GALR1,IP6K3,ACSS1,GART,WASF3,KIAA1841,SULT1C4,SESN1,GLS,TOX3,MSL3,DCLK2,FERMT2,LILRB4,GPM6A,GPM6B,B4GALNT4,GPR19,GRIA1,GRIK1,SPACA9,GRM2,PRDM5,GRM7,KIF3A,ADAMTS6,MUM1,PADI2,ZHX1,VSIG4,AGBL5,OPALIN,CELF5,HTR5A,MSL1,LINC00667,RAB41,GAREM2,SCIN,IL6R,ZNF678,OLFM3,KCNA6,CREG2,LAMA2,SYTL4,FGFBP3,NCOA7,ZFYVE27,MAP4,MAP6,LYPLAL1,MAT2A,MBD1,CHIC1,TM6SF1,MEIS1,PPM1L,AFDN,BCO1,CTNNA3,MXI1,LAYN,MYO5A,MYO7A,ZNF862,NAP1L1,SFR1,NF1,NHLH1,NODAL,NPR2,HCN1,NTRK2,NTRK3,OPA1,PAK3,PCDHGC3,PCDH9,PCSK2,PIRT,PDPK1,PFKFB3,NLGN3,SERPINE2,ANLN,XRN1,KCTD15,NLE1,PLCL1,PLP1,TRHDE,PRRX1,MAGEL2,SLC36A4,TNPO2,NXPH1,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,PRKACB,GRAMD1C,PIGG,CNTLN,PTAFR,UHRF1BP1,ZSCAN32,TMEM255A,RALGDS,SH3TC2,NWD1,RASGRF2,RFX2,SEC61A2,RNASEL,C12orf49,ELP2,NEK11,ZC3H14,KIAA0895L,GLDN,ACER3,ATAT1,SALL1,SATB1,LRFN5,LRRTM4,PRCD,SCP2,GALNT10,FOXRED1,MRAS,TRA2B,COPZ1,MAGI3,CHD9,FHOD3,CTXN2,CLSTN1,RPH3A,PPP4R3A,DHX30,RUFY2,SLC6A1,SLC6A7,ARHGEF40,SLC9A5,SLC11A1,ZFP1,RCOR3,INAVA,LIMCH1,MBD5,SNRPN,UNC80,SCN3B,DOP1A,TRERF1,SOX10,FNBP1,DOK5,ZSWIM8,ENKUR,NPAS3,SPART,ATP10B,ITPRID2,SMOC1,NECAB1,SYT11,ZC3H4,SYN2,TACR1,DNMBP,PDLIM2,UNC5D,TMEM136,MGRN1,ATMIN,SIN3B,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,ARHGEF12,USP32P1,FRYL,CCDC173,SIK3,VWCE,PMS2CL,DICER1,SIRT1,ZFPM2,ITGB3BP,GALNT17,TIAM1,MTMR14,TIMP4,BHLHB9,TLR4,DAAM2,RIMBP2,PRRT1,CSMD1,C5orf64,SEZ6L,TPD52,ZNF346,SYNPO2,FNDC5,KCNE5,ANO5,TTTY15,CLHC1,CADM1,MEAF6,WIPF1,WRN,SLC13A3,XPO1,SF1,ZIC3,LYPD6,ZFAND5,SMARCAD1,SYNC,EMSY,PRDM2,DNALI1,LRP8,SLC38A1,LINC02210,ADAMTS9,HPS4,NAV2,FAM47E,PCBP4,MPPE1,C12orf4,FZD3,UBE3B,ZNF248,VANGL2,FRMD6,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-18b:mirSVR_lowEffct hsa-miR-18b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.56E-146 2.00E-142 7.13E-145 6.57E-144 379 1602 "ADARB2,KLHL32,TMEM132B,CCDC85A,GALNT13,RNF157,ADD2,AXIN2,SLC12A5,ESYT2,DPY19L2P4,RTL9,HACE1,KIAA1324,OSBPL8,AK2,SEMA6A,USP35,FAM135A,DPP10,ANK2,LCORL,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,EPB41L5,UPRT,GPAM,NT5C3B,APOC2,AQP6,PDXK,ARHGAP5,CDK13,NUMB,ASTN1,DDX3Y,CHID1,EIF4G3,DPY19L3,ADGRB2,LINC00847,BBS2,SEC11C,DST,SYNJ1,C1QC,MYRF,CACNB2,CACNB4,PTBP2,CAMK2G,HIP1R,RHBDL1,NFS1,LDB2,CD86,NEURL1,MAGI1,CCPG1,TAOK2,NRXN3,TPP1,DGCR9,VAX2,SULT4A1,CNR1,ABI3BP,MFSD4A,CP,FAM171B,CLOCK,CRY2,ANKRD44,SNCAIP,TENM4,CSF1R,SEC24C,CSNK1E,SIPA1L1,SLITRK5,CTH,CTNND2,MYADM,DCAF8,KIAA0513,TBC1D5,KIAA0586,CTIF,GIT2,ARMCX4,ZNF804A,DGCR5,MYEF2,CNIH3,TMEM130,BLOC1S6,SRGAP3,DNM1,DYNC1I1,SLC12A6,ABCC5,ABCC9,E2F5,USH1C,EDNRB,PHC2,EGFR,MBNL2,KMT5B,TNK2,TMEM35A,MFSD10,GPHN,ERBB2,DENND4A,ANKMY1,SIRPB1,F3,TUBB4A,ATP8A1,CHST15,FKTN,ZSCAN30,ZNF589,GORAB,FGFR3,UBE2E3,SYNCRIP,FLT1,PSD2,EFCAB2,NBEA,SMC2,UFM1,STAMBP,CAMKK2,CELF1,DACH2,HHIPL1,TPPP3,NRG3,GAB1,GABRB1,GABRB3,GABRG2,NEK6,IP6K3,ZNF559,DISC1,ATP8A2,LRRC37A6P,KIAA1841,DNER,ALDH1L1,ZNF276,COPS8,SPIN1,GLS,WDFY3-AS2,ADGRA3,GPD1,TDRKH,LILRA1,GRIA2,DIDO1,GRIA4,PLCD4,GRIK3,ADAMTS13,GRM1,RNF165,TMEM25,PTGDR2,PACSIN2,ATXN2L,VSIG4,ELOVL5,HMGB1,HMGCL,AGFG1,DHX35,HTR2A,MSL1,FAM95B1,RBPJ,LRRCC1,IGSF1,METTL21A,KCNA1,KCND2,KCNN2,KIT,IPO5,STXBP5,KTN1,SYTL4,VWA5A,HECTD2,ARHGAP12,ZNF667-AS1,MAP4,MARK1,MAT2A,ADAM11,MEF2C,MEIS1,ERICH3,JAKMIP3,SCG3,TAGLN3,CTNNA3,MDGA1,MYO9A,FXYD6,NCAM1,NEUROD1,NOVA1,NTRK2,NTRK3,NUMA1,OGG1,OLR1,LOC100128398,OPRL1,PAX6,PBX1,DPY19L2P2,PCDH9,CDK18,SLC10A4,GNG2,PFKFB2,PFKFB4,PCDH18,PLXNB1,C11orf49,ANKRD16,RC3H2,EPB41L4B,POU6F1,PPM1B,PPP2R5E,EPDR1,BCAS3,WBP1L,NCR3LG1,BDNF-AS,PTHLH,TMEM260,ZSCAN32,PTPN13,PTPRE,PTPRG,PTPRO,FAM120C,PTPRZ1,RAB5B,PID1,CCDC40,SH3TC2,ZCWPW1,ARID4A,REV3L,RGS4,RGS7,RGS12,TTLL7,LGI2,ALG9,GSTCD,ROBO1,ELP2,PCMTD2,EPHA10,BAALC,ADAL,TCP11L1,LRRK2,KCNIP1,CLIP1,FAM182A,TRAPPC13,FAM192A,FOXRED2,SAFB,SEMA6D,ATXN1,SCN4B,SCP2,SMPD3,TRIM46,SCAF8,PPP1R9A,FERMT1,FNDC3A,CLSTN1,ABLIM3,LRRC55,SEPHS1,CCDC88A,ARFGAP1,NAXD,MAST1,CDK5RAP2,IFT122,IGSF9B,ANKRD36,SNCA,SNRPN,PALLD,MYO16,KDM4B,WDTC1,ZCCHC24,FNBP1,ZSWIM8,CLUAP1,SRPK2,CLASP2,POGZ,MESP1,SSTR2,SSPO,ZSCAN29,GSE1,NSFL1C,NECAB1,ARC,SYN2,SYPL1,DNMBP,CAMSAP2,KLHL4,TCF7L2,TRIM2,WDR7,RALYL,FAM189A1,PCDHB4,USP32P1,GPRIN3,DICER1,ZFPM2,CRB1,TGFBR3,ERCC6L2,TMPO,R3HDM1,CSMD1,TNS1,RBFOX2,TPM3,WBP2,CHST5,UBE2H,OSBP2,ZNF709,VLDLR,ZIC2,ZNF540,PLPP4,ZNF154,REEP1,POLR3H,PLPPR5,TFIP11,WNK1,RGMA,CSDE1,RNF103,GAL3ST3,PARP11,PDSS2,ST7,UBE3B,TRAM2-AS1,SLC4A10" MicroRNA hsa-miR-3198:mirSVR_lowEffct hsa-miR-3198:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-146 2.43E-142 8.65E-145 7.96E-144 393 1721 "CLK4,XKR4,CSMD3,NDRG3,ADAR,PLEKHG5,ADD2,SLC12A5,GRAMD1B,KIDINS220,SNX32,KCTD16,KIAA1324,OSBPL8,TAOK1,ANK2,FGD2,PHF12,APBA2,CDC14B,MIER1,KIAA1614,SEMA4G,MADD,ARHGAP5,ARNTL,LINC00173,DACT3,PCDHGB4,NUMB,ATP1A2,EIF4G3,ATP2A2,ATP2B2,ATP2B3,N4BP2L1,BACH1,ADGRB2,RGS9,SYNJ2,SCAPER,GPC2,BSN,CA4,CA12,CACNA1D,CACNB2,PTBP2,CAMK2G,VSTM2A,SPAG9,NFS1,CBLN1,METTL6,NEURL1,CDK11B,REPS2,CHM,ZBED5,TAOK2,NRXN3,CLTC,MAP4K4,LY86,TMEM155,AKAP6,CABP1,ABI3BP,RCHY1,SMARCAL1,MFSD4A,CP,SEC31B,PREPL,CSF2RA,CSNK1E,FAM169A,PHF14,CFAP61,CTNND1,CX3CR1,MYADM,ARHGAP32,EARS2,DAPK1,AIF1L,DNAL1,DGCR5,RUSC2,CEP170,POM121,RHOBTB1,SGSM2,DLG2,HS3ST4,SLC29A4,GNE,ARRDC4,DNM1L,PHC2,FCF1,KLHL5,CELSR3,FAM13A,SUGP2,EGFR,MBNL2,SORBS3,IRAK4,ELAVL4,USPL1,TUBD1,ETV1,TLR7,SIRPB1,ADGRV1,TMEM132C,ZSCAN30,PPP1R1B,GTF2IRD2,KIAA1109,BAIAP2,FHL1,POLK,CAP2,SEMA4D,PSD2,SLC37A3,NOP56,WDR83,CAMKK2,ATP6V1H,CELF1,DACH2,PNMA2,SDCBP2,GABRA5,GALNT15,DENND2A,GAD2,BRPF3,ARPP21,ZNF559,DISC1,GBX2,SULT1C4,MSTN,GGT5,LYVE1,CRCP,DBF4,GLYR1,GLS,MSL3,LNX1,PSRC1,GPD1,PRUNE2,FUT10,PRLHR,GPR12,STON1,PLPP7,NR3C1,GRM2,CIT,RNF165,KAT7,GSTT2,MFSD2A,GUCY1B1,FAM222A,UBE2QL1,FRMD5,LINC01102,AGBL5,NEGR1,IGFBP1,NKD1,DOCK7,IL11RA,INPP5B,ITGAM,SLC35G1,KCNB1,KCNJ16,KCNMA1,GATD1,CREG2,KIF5C,LINC00634,KLC1,IPO5,SFXN5,CLEC18A,MAN2A2,MAT2A,CHIC1,MDM4,MEIS2,KITLG,MN1,MOG,CD200,MPP2,PTOV1,MT3,MTR,MYO9A,P2RY13,CCDC13,SLCO1C1,NOVA1,SMIM11A,NTRK2,TBC1D25,ODF2,OGG1,PAH,GLIPR1L2,PCDHGC3,PCSK5,PDE1A,PDE1C,PIRT,PDYN,GDAP1L1,CCSER2,RETREG1,FXYD1,PLP1,ZNF426,PLXNB1,PLXNB3,RC3H2,SDK2,PACSIN1,LRRN3,PPP3CB,PRKCB,PRKCG,GRAMD1C,DIRAS2,CYBC1,SYTL2,MDGA2,NCR3LG1,ZSCAN32,PTPRE,PLEKHB2,RALGDS,SLC25A41,NWD1,ROGDI,OXR1,RASGRF1,TRIM68,RGS4,ARHGEF10L,ZNF532,SUGCT,TMLHE,C12orf49,KLHDC8A,ARMC5,CARF,ROBO2,ELP2,NEK11,UEVLD,SGSM1,LRRK2,PTGR2,KCNIP3,RTKN,RXRG,DGLUCY,MAPK12,SEMA6D,CSRNP3,DRAXIN,SCN2B,LRRTM4,SCNN1D,SCP2,TNFRSF19,SEC14L1,GALNT10,SUPT20H,SH3GL3,NTNG1,AMBRA1,FHOD3,ZNF365,WDR47,FAM214B,KANSL3,PKNOX2,SLC6A11,YPEL4,ARHGEF40,SLC14A1,SCMH1,BTBD7,CDK5RAP2,SMARCD3,MYH15,ANKRD36,SNCA,TMCC1,FAM219A,DOP1A,ZSWIM8,NMNAT2,EMC1,ARHGAP26,C11orf87,CLSTN2,STOX1,SYT11,ZC3H4,SYNE2,ARC,TAC1,KAZN,FAM208A,KLHL4,WSCD1,ACSL6,DMXL2,CUX2,ZEB1,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,PCDHB3,PCDHA5,FRYL,RNF216P1,PMS2CL,TGFBR3,SLC44A1,THRA,TLL2,BEX4,TPD52L2,TPM4,CHST5,RUNDC3B,TRO,TRPC3,TRPS1,PPIL6,TSN,ANO5,TTTY15,CADM1,RPL7L1,AMOT,VIPR2,RICTOR,ZNF708,TCEAL7,DPYSL5,PCBP1-AS1,MEIS3,SLC30A4,CADM2,STMN4,SCG2,SIGLEC10,PCDH15,SLC17A7,PCBP4,RGS7BP,FAM13C,MARCH8,DPF3,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-148a:mirSVR_lowEffct hsa-miR-148a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.32E-146 2.99E-142 1.06E-144 9.76E-144 407 1843 "KCNH8,ASIC1,ACHE,NCKAP5,CSMD2,ADARB2,ADCY2,ADD2,PLEKHH1,GRAMD1B,USP31,PWWP2A,DPY19L2P4,MTA3,SLC24A4,OSBPL1A,CC2D2A,HFM1,LRRC7,SRPX,ARHGAP20,SYT13,MRTFA,ZFAT,OGT,ANK2,CCDC146,EPB41L5,TNRC6C,USP37,SHTN1,PDXK,LINC00173,CDK13,MARCH3,CAPRIN2,NUMB,ASTN1,ATP2A2,ATP2B3,MTMR9,ATP6V0A1,BACH1,MPDZ,BCL2L2,BID,KSR1,MTMR2,CACNA1B,DDR1,CALM1,KALRN,CAMK2A,LDB2,USP2,SEPT7,CDC25B,TIGD7,TBRG4,KMT2C,ZFYVE9,CLCN3,KIAA1549L,NRXN1,TPP1,CLTC,FBXO7,FAM189A2,TJP2,FADS2,MAP4K4,NIPBL,CNR1,IQCK,PCYT1B,LETMD1,SLC4A7,IFFO1,SLC35F1,CS,CSF1,PDE4DIP,PLXNA4,PPP1R16B,APPL1,PHF14,CCDC144A,KATNAL2,DCAF8,TBC1D5,ARMCX4,ARMCX2,SPATA2,ZEB2,ELMO1,HP1BP3,CEP170,RHOBTB1,G3BP2,USP3,DNAH9,SLC29A4,CDON,SLC12A6,DPYSL2,ACOT8,PDCD6IP,DNAJB6,DYRK1A,ABCC5,WDPCP,EDNRA,EDNRB,HEYL,CELSR3,APH1A,EGFR,KMT5B,RASA4,AASS,EIF4G2,PAN3,EPB41,EPB41L2,MTSS1L,GPHN,SLC43A2,STX2,EFS,TAOK3,ATP8A1,ST3GAL6,FCGRT,FDFT1,OLFM1,AMOTL2,SCARA3,SEC23B,FOXF2,SEMA4D,NOP56,NBEA,TACC2,PDLIM5,ZNF605,NRG3,GABRB1,GALNT15,GALC,SIGLEC8,SEPT9,ALDH1L1,TUBGCP4,HEPN1,RNPS1,SPIN1,GLS,TOX3,AIFM3,KDM2B,LOXL3,GPD1,GPD2,TMEM121B,RAPGEF4,ADAMTS13,SERP2,GRM2,GRM7,ZNF496,LINC01089,FAM19A2,PTPN5,RASSF8,FRMD5,PACSIN2,HLF,SYNPO,HNMT,TLX1,AGFG1,HSP90AA1,HTR5A,ICA1,ZNF546,IGF1,C5orf24,INPP5B,LRRTM3,JAK1,SLC35G1,KCNH1,KCNJ16,KCNK1,A1BG-AS1,VWA5A,PIK3AP1,ZFYVE27,MAP4,AQP11,MBP,CHIC1,MDM4,MEIS1,MKLN1,MMP16,ERICH3,COMMD5,MT3,MTR,NEXMIF,NACA,NAP1L1,NCAM1,RCOR2,NELL2,NFYA,NOVA1,NTRK2,NUMA1,TBC1D25,OPA1,OPCML,OPHN1,P2RY1,GPR137C,ZDHHC22,SNTG1,DPY19L2P2,PCSK5,PRTG,PDE2A,PDE3B,PDE4B,PDE4D,PDGFRA,PIK3R1,SNX10,PKM,GPSM2,NLE1,FTO,PLP1,MTRF1L,PLXNB3,PRIMPOL,LRP12,ING3,MBOAT7,SH3KBP1,MED1,CCDC144B,PPP2R2C,PPP2R5E,PKIA,PRKCZ,EPDR1,MAPK9,HYDIN,MASP1,SLC22A23,PIGG,ELOVL2,PTPRE,PTPRG,TUG1,QDPR,PLEKHB2,ATG16L1,ROGDI,RBBP8,PRRT2,RFX3,SEC61A2,RIC8B,ZNF532,TMEM206,UEVLD,BAALC,ZC3H14,ACER3,RTKN,CLIP1,RTN1,SEMA6D,CSRNP3,SCN2A,SCN2B,SCN8A,MRAS,SUPT20H,TRA2B,RASA3,PPP1R9A,MYO18A,NTNG1,AMBRA1,SLITRK3,SYBU,SLA,EPN2,DHX30,KANSL3,PKNOX2,SLC8A1,ARHGEF40,CCDC88A,TRIM67,SLC12A2,BTBD7,CPEB4,RCOR3,IFT122,SNAP25,SNCA,KIF13A,FAM126B,MYO16,UNC80,PDZD2,BDP1,EMC1,KDM4C,TEX2,CLASP2,CLSTN2,ERBIN,STAU1,DIP2A,STXBP1,AJAP1,PRRC2C,C3orf70,PLCB1,TMEM150C,SYT1,C12orf76,TAF9,EXOC7,TAL1,AGTPBP1,FBXW11,TMEM136,EHBP1,TCF4,ZFP90,TCF7,NAT16,DOCK9,PHF24,PCDHB4,ARHGEF12,GPRIN3,LEFTY2,HHIP,GZF1,MTMR14,NR2E1,HEY2,R3HDM1,C5orf64,RBFOX2,CDK20,SYNPO2,METTL3,TRPS1,ZMYND8,HIRA,UBE3A,UGT8,SLAIN1,OSBP2,FLRT2,ZNF709,VAV2,TBC1D15,KLC2,CLDND1,RICTOR,PCDH20,ZNF711,SLC26A10,LYPD6,FSTL5,EML6,DPYSL5,UPF3A,MFF,CADM2,PRDM2,SLC38A1,RGMA,XKR7,SNX27,KCNAB1,FAM47E,SLC17A6,PARP11,UBE3B,KAT6A,CASC15,CERS6,FAM219B,ZNF248,SLC39A12,SLC4A10,FAM198A" MicroRNA hsa-miR-4276:mirSVR_lowEffct hsa-miR-4276:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.43E-146 3.05E-142 1.08E-144 9.93E-144 412 1887 "RALGAPA1,ASPHD1,ABHD6,KDM5D,TMCC3,SLC12A5,GRAMD1B,RNF150,BEND6,NLGN4X,SLC44A5,AK2,TAOK1,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,CDK13,DACT3,DDX3Y,ATM,ATP2A2,RNF182,DPY19L3,RIPK1,TTLL9,BACH1,SNAI3-AS1,ADGRB3,MPDZ,PROM1,OSGIN2,CACNB2,THSD7A,CAMK2D,CH25H,NFS1,CBR1,METTL6,USP6,MTMR7,C1orf52,ZBED1,CDH2,CDH8,LOC730101,CLGN,CASC2,KMT2C,RAB33A,CLU,FADS2,QKI,SULT4A1,NIPBL,ARMC8,AKAP6,ZFP28,FAM171B,CREM,HAPLN1,CS,AATK,RGS6,SEC24C,FEZ1,MICAL2,CSNK1E,OSBPL3,PDE4DIP,PHACTR3,UBXN2A,PHF14,CTNND2,NRSN1,USP6NL,ECE2,CCDC144A,BOC,TCAF1,DCAF8,TBC1D5,DGKG,DCC,PLEKHM1,HEPH,TMEM130,FBXO25,ZC3H11A,RHOBTB1,SNAP91,SV2B,SRGAP3,CHRDL1,DLG2,RAB39B,HS3ST2,DOCK2,DMTF1,RCAN1,TOM1,ABCC5,ABCC9,KRBA2,E2F6,EDNRB,ATL1,CNNM1,SH3GLB1,GPR61,SUGP2,ABI2,EIF4G2,ELAVL2,TMEM35A,C8orf37,DCTN4,ENO2,EPB41L1,EPHA5,SRRM1,EPS8,ETV1,ANKMY1,EXTL2,NRN1,CLVS1,SH3YL1,CORO2B,EFEMP1,DLC1,ZNF589,FER,MED12L,KIAA1109,SUCO,SYNCRIP,FLT1,NELFCD,C2orf88,SMC2,ATP2C1,ZNF605,STAU2,MEGF10,GAB1,GABRA1,GABRB3,HBS1L,RAPGEF6,ARPP21,NEK6,IP6K3,IQGAP2,SIGLEC8,ZNF559,GART,GCK,ARFIP1,AHDC1,PPARGC1A,MALT1,LYVE1,TTBK1,CRCP,TCERG1,MSL3,LNX1,LILRB4,GPD1,ATF7,CNTRL,ATP2B1-AS1,DIDO1,GRIA4,GRIK2,NR3C1,FAM19A2,AP4S1,MUM1,HPS5,FRMD3,MIER3,HLF,HMGCR,AGFG1,LRRC75A,IGFBP1,DIPK1A,ZNF385B,ITGA7,ITGAM,ITGAV,JAK1,KCNJ3,KCNJ9,KIF5A,KTN1,INSYN2,LMO2,HECTD2,C2orf80,GPR155,MAN2A2,LYPLAL1,CHIC1,MDM4,MEF2C,MEIS1,AFF1,MMP16,MPP2,MSI1,JAKMIP3,ADAM22,CTNNA3,RSPO2,MYO9A,NAP1L2,ZC3H12B,NDUFA5,ALDH1L2,NHLH1,NOVA1,NPTX2,NTRK2,IGSF11,OCRL,OPCML,CLDN11,P2RX7,GPR137C,GLIPR1L2,SNTG1,PBX1,PDCD2,PRTG,PDGFRA,ENPP2,TMOD2,PFKFB2,PFKFB4,SERPINE2,PIK3CD,XRN1,PKM,NLE1,ST8SIA5,JAKMIP1,PLP1,HMGCLL1,MTRF1L,PRIMPOL,PMP22,MAPKAP1,STRN3,SCHIP1,EPB41L4B,TMEM235,PTPA,CEP41,MAPK4,BCAS3,WBP1L,MDGA2,STK32A,ZSCAN32,PTPRB,CASTOR1,PTPRH,FAM120C,NKAIN1,TUG1,SLC25A48,NWD1,DBX2,ZYG11B,REV3L,GTDC1,MRPS18A,SLC25A36,RNASEL,RPRD1A,TMLHE,C12orf49,ROBO2,TMEM100,NEK11,UEVLD,FBXW7,KIAA0895L,PRR5L,TCP11L1,WLS,ZNF331,TRAPPC13,FAM192A,ATXN2,LRFN5,LRRTM4,SCN8A,SCP2,SOX6,SFPQ,SUPT20H,NLGN4Y,SH3GL3,FRMPD1,KIF16B,SHC4,FNDC3A,SYBU,ST3GAL3,ABLIM3,SLA,ZNF365,PREX2,BTBD3,NAPB,SPHKAP,ZKSCAN3,CXXC4,SMARCD3,IFT122,RIMS1,SNCA,SNRPN,PALLD,TMCC1,MYO16,SON,WDTC1,SOX5,SP4,SPP1,ZBTB43,SPART,C11orf87,POGZ,LARP4,KANK1,GSE1,VPS13A,TMEM150C,ARC,MTCL1,SEMA4A,UNC5D,TBL1X,VWA3A,ATMIN,SATB2,ZEB1,TPCN2,TRIM2,TCF12,DOCK9,TMEM151B,RALYL,PCDHB3,AKNA,GPRIN3,TEK,PMS2CL,DICER1-AS1,THRA,TIAM1,TMEM9,CDK20,ZNF346,TRO,RUSC1,SSBP2,SGK3,UBTF,UGT8,FLRT2,WRN,GUSBP1,CFAP298,ZBTB14,ZNF23,SLC26A10,MKRN3,ZNF138,CELF4,TMEM237,EML6,PCBP1-AS1,ZFAND5,SMARCAD1,CA10,SLC38A1,STOX2,PCDH15,GAL3ST3,KCNAB1,WIPF2,C12orf4,UBE3B,PAK5,PHTF2,FBXO36,CERS6,ADAMTSL3,ZNF248,RNF170,VANGL2,FRMD6,IFT88,NETO2,DPF3,SOCS4,SENP7" MicroRNA hsa-miR-26a:mirSVR_highEffct hsa-miR-26a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.11E-146 3.43E-142 1.21E-144 1.11E-143 363 1473 "SDE2,ACADM,CLK4,ACTN2,ERMN,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HACE1,TXNDC16,SMIM17,ALCAM,ANK1,LRCH2,EP400,APAF1,APC,TNRC6C,SHTN1,MIER1,TMEM263,RGS20,CDK13,CCDC74A,ATP1A2,SLC4A4,ATP1B3,ATP2B1,LINC00847,BID,GPR146,BMPR1B,DST,ST3GAL5,FUBP1,SCAPER,JAZF1,OSGIN2,CACNB2,KALRN,VXN,MAP7,KRIT1,USP6,LGI1,LARGE1,CFL2,SRSF11,SOCS6,CHN2,MS4A7,KMT2C,CLCN3,NRXN1,CLTC,TJP2,DNAJB5,QKI,TMEM184B,CNR1,AKAP7,COL4A5,SLC4A7,BAG4,ACBD5,SLC35F1,CLOCK,C2CD2,RBM39,HAPLN1,GDA,ARHGEF10,PLXNA4,DZIP3,ERC2,GREB1,CTNND2,ST18,RUBCN,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,KCTD8,DAPK1,PITPNC1,JAKMIP2,ZEB2,MFAP3L,C2CD2L,PLPPR4,SACS,G3BP2,WDR20,DLG2,EXOG,GRIN3A,DMD,OLIG1,USP3,DPYSL2,PDCD6IP,DTNA,DYRK1A,FCF1,TMTC1,FSD1L,EGFR,EIF4G2,EIF5,TENM1,ELAVL2,CALCRL,PAN3,LRRC17,EPHA5,EPHB1,STX2,ETV1,RPS6KC1,TMEM132C,EFEMP1,ATP8A1,GORAB,KIAA1109,FGF14,CAMSAP1,MEX3B,IP6K2,SEMA6C,SEMA4D,SGIP1,NOP56,UFM1,DACH2,NEURL4,GABRA2,ZNF44,CAB39,FAM184B,ARPP21,GALR1,NEK6,ACSS1,TUBGCP4,SRCAP,PPARGC1A,GK,GLS,TNRC6A,ZNF638,KCNMB4,GNAL,GRB10,DIDO1,GRIA4,RFFL,GRM1,GRM7,CLASRP,LINGO1,ADAMTS6,UBE2QL1,ZHX1,ATXN2L,LINC01102,MIER3,HNF4G,CELF5,HTR2A,MSL1,ZIC5,IL6ST,DIPK1A,TUBB2B,JAK2,KCND2,KCNK1,STXBP5,KTN1,LAMP2,SMAD1,MAP2,MARK1,MAT2A,MATN2,MITF,AFDN,MMP16,MOG,CD200,ZNF680,BLOC1S2,ZNF92,MTTP,MXI1,MYO9A,NEK1,CNOT4,SLC11A2,NUMA1,GPR137C,PCDH8,PCDH9,PDE3B,SLC10A4,BEST3,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,PLCL1,PLP1,PCDH18,HMGCLL1,PURG,PMP2,ING3,RETREG2,FA2H,MINDY2,PPM1B,CRLS1,PPP2R5C,PPP3CB,RANBP3L,CEP41,MAPK10,GRAMD1C,HYDIN,VPS13C,MDGA2,PIGG,PXK,STK32A,ZSCAN32,PTPN13,PTPRD,FAM120C,TTC13,ZNF615,PPP2R3C,CEP97,TMEM255A,RALGDS,ZCWPW1,VEPH1,SLC6A15,ZYG11B,ERI2,UBR7,RGS4,SLC25A36,NUDT11,RPRD1A,ZFHX4,CARF,GSTCD,ARMH4,GLDN,CNTNAP3,LGR4,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,GALNT10,SFPQ,MRAS,KIF27,CHD9,FBXO11,NLGN1,SLC1A6,RUFY2,ZNF430,CCDC88A,SLCO1A2,TET1,CPEB4,SORCS3,MYH15,ANKRD36,LIMCH1,CMTR2,PALLD,TMCC1,USP33,ZCCHC24,CAND2,ZC3H13,KIF1B,NPAS3,TAB2,CLASP2,TROVE2,STOX1,EPB41L3,LARP4,STAC2,GSE1,NECAB1,SYNE2,VAMP1,NUDT10,PLCB1,ANKRD28,SYT4,POPDC3,PJA1,DNMBP,FAM208A,KLHL4,TCEA1,TCF7L2,RALYL,USP32P1,FRYL,FAM200B,AP4E1,ERCC6L2,FAM124A,C5orf64,AMACR,STXBP4,TRPC3,PPIL6,DCBLD1,TSN,ANKRD20A2,TTC3,TTPA,ZKSCAN5,AMOT,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,KCNT2,MKRN3,ZBTB38,ANKS1B,WNK1,EMSY,CIAPIN1,MDH1B,MPPE1,WNK3,PDSS2,CASC15,JMJD1C,RNF170,VANGL2,NHSL1" MicroRNA hsa-miR-3166:mirSVR_lowEffct hsa-miR-3166:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.12E-146 3.44E-142 1.21E-144 1.11E-143 410 1870 "RALGAPA1,SYN3,ASIC1,RBM10,AS3MT,TKTL1,ADCY6,RNF157,GRAMD1B,PWWP2A,PTCHD1,FAHD2CP,OLMALINC,MTA3,AP1B1,GPR158,KIAA1324,TXNDC16,TAOK1,SEMA6A,SPOP,LTBP4,DOC2A,MYH7B,GAS7,PHYHD1,USP37,APP,CDC14B,MADD,IGDCC4,ZFYVE28,ARHGDIA,ARSE,SLC4A4,ATP1B3,ATP2A2,MTMR9,RIPK1,ADAM15,BCL7A,CFLAR,BMP7,SCAPER,MYRF,CDK5R2,THSD7A,CALM1,PTBP2,CAMK2A,CAMK2B,VSTM2A,BRSK2,MAP7,PRC1,ENTPD6,CDC25B,DCLK1,DIS3L,RCBTB2,SRSF11,CHRNA4,JAM2,RAB33A,KIAA1549L,COG1,C4orf33,QKI,SRP14-AS1,NIPBL,ARHGEF6,CNR1,AKAP6,AKAP5,IFFO1,RTTN,MYRIP,CNRIP1,MFSD4A,PNKD,CLOCK,RBM39,ANKRD44,TRIM69,CSF1R,CSNK1G3,NCAN,PDE4DIP,FAM169A,CTNND1,NRSN1,CX3CR1,ECE2,BOC,HDAC9,TOX,PHF19,LONRF1,MATR3,DNAL1,ARMCX4,SPATA2,YTHDC1,C2CD2L,KLHL3,LYPD1,GSDME,DDX46,AK5,RABGAP1L,DLG2,DLX1,GRIN3A,RAB39B,DNM1,HS3ST4,SLC29A4,SLC12A6,PDCD6IP,MAMLD1,AASDH,EEF1A2,CNNM1,HEYL,SEMA3D,PHF20L1,APH1A,AASS,RGS17,VPS13B,LRRC17,EPHB1,SLC43A2,EPS8,DENND4A,EFS,SPEG,CDKL3,RTN3,F3,CLVS1,KAT8,ZNF589,SLC9B2,FGF11,FGFR1,AMOTL2,CAP2,SEMA6C,FLT1,TMEM107,ARFGAP2,NSG2,PNMA2,KBTBD12,TMEM151A,NRG3,STAG2,GAB1,GABRB1,GAD1,GAD2,BRPF3,ZMYND11,GHDC,ATP8A2,INPP5K,WASF3,KIAA1841,ALDH1L1,GGT7,GGT5,GHR,ZNF276,STARD3,MAP7D2,GNAO1,GOLGB1,GPD1,GPD2,DIPK1C,LILRA1,CECR2,GRB10,DIDO1,RFFL,GRM5,GRM8,ZNF496,KIF3A,LINC00839,PTPN5,MFSD2A,AP4S1,SOX21,FAM107A,ATOH8,OPALIN,HSPA1L,CELF5,MSL1,DISP2,PLD5,ZNF678,SLC6A17,ZNF385B,ITGAV,SLC35G1,KCND2,GPR62,KCNK2,KIF5C,STXBP5,LAMP2,HECTD2,PACRG,MARK3,MAT2A,MBD1,SYT9,CHIC1,MEF2C,KCTD6,MID1,MN1,MT1M,CTNNA3,MTR,RSPO2,MXI1,RTL5,HNRNPM,NAP1L1,ZC3H12B,VWA2,NOS1,NTRK2,OCRL,ZNF827,TREM2,PAK3,PCSK1,PCSK5,PENK,PFKFB2,CDK14,CCSER2,GPSM2,NLE1,ST8SIA5,PLCD1,FTO,PLXNB1,PNMA3,TRHDE,CDIP1,LRP12,SCHIP1,MAGEL2,EPB41L4B,NXPH1,PPM1B,PPP2R2B,LRRN3,CRLS1,PPP3CB,PPP3CC,KANSL1,PPP5C,PRKAB2,PKIA,PKN2,PRPSAP2,RELN,WBP1L,DEF8,CNTLN,UHRF1BP1,MTMR10,PTPRE,PTPRG,NKAIN1,QDPR,RAP1GAP,NWD1,ENOX1,ZNF493,RBBP6,KHDRBS2,RET,GTDC1,KCTD17,PBRM1,ZFHX4,RNH1,RERGL,TMLHE,C12orf49,ROBO2,RPE65,ARMH4,TCP11L1,ATAT1,KCNIP3,YJEFN3,TRAPPC13,FOXRED2,SARS,ATXN2,ATXN7,SCN2A,SCN8A,PRCD,SCP2,FNIP1,CASC3,PPM1E,FERMT1,FNDC3A,NLGN1,PAAF1,SLA,SLC4A3,RUFY2,LRRC55,SLC9A5,SLC12A2,TMEM132D,ATF7IP,SLC22A4,CDK5RAP2,RCOR3,ANKRD36,INAVA,SNAP25,SNCB,SNRPN,TMCC1,DOP1A,WDTC1,CLUAP1,SPTAN1,CDK19,DDN,CLSTN2,POGZ,SSPO,SEPT8,CEP68,SEPT3,STXBP1,VPS13A,SYT1,ATP11A,KAZN,MLST8,TAL1,ADGRL3,FBXW11,DMXL2,TPCN2,AZIN2,NSD1,CCDC173,CYB561A3,PMS2CL,CDH22,FBXL16,THRA,TK2,DDHD1,TLL2,LILRA4,RASD2,FNDC5,KCNE5,FAM155A,CLEC2L,FLRT1,PLEKHH2,WIPF1,CLDND1,GUSBP1,SF1,ZNF708,SLC26A10,LYPD6,EML6,DPYSL5,ZFAND5,CADM2,DNALI1,SLC38A1,SCG2,CIAPIN1,VPS35L,NAV3,SLC17A6,MVB12B,MARCH8,UBE3B,PHTF2,CASC15,NUP214,ACTR3B,RSPRY1,RNF170,ADAMTS10,SNX14,GAN" MicroRNA hsa-miR-520g:mirSVR_highEffct hsa-miR-520g:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-145 5.74E-142 2.01E-144 1.85E-143 353 1395 "RALGAPA1,SYN3,CSMD3,KLHL32,ESYT2,BEND6,NLGN4X,SLC24A4,ZNF608,INTS2,RTL9,KIAA1324,WDR35,ALCAM,GPRASP2,PARG,APC,CDK13,STK33,EIF4G3,ATP2A2,ATP2B1,NOL4,ADGRB2,ADGRB3,MPDZ,FUBP1,JAZF1,SGCE,OSGIN2,CALB2,CAMK2D,SLC25A14,CAST,HIP1R,CBFA2T2,DGKI,MAGI1,CCPG1,CLGN,B4GALT6,LHX2,RAB28,ABCG2,DNAJB5,CNR1,AKAP7,ARMC8,FAM149A,AHCTF1,ACBD5,CDC42BPB,CREM,ENTPD4,ANKRD44,GDA,LRRC3B,CSNK1E,OSBPL3,SLITRK5,CTNND2,RUBCN,GPRASP1,RIPOR2,TOX,DBN1,HEPH,TIAM2,DDX46,RHOBTB1,SNAP91,G3BP2,DLG2,RAB39B,DMD,USP3,DMTF1,DNAJB6,DYRK1A,DNM1L,ABCC9,FAM135B,EDNRA,ATL1,FCF1,RASGRP1,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,IRAK4,COPS4,PLEKHA1,C8orf37,PAN3,DCTN4,TUBD1,EPB41L2,EYA1,F3,CLVS1,WAC,ACSL4,SCML2,CEP78,FDFT1,GTF2IRD2,FGF12,FOXG1,FOXF2,RGPD5,IQCG,ANKFY1,C2orf88,EFCAB2,JKAMP,TRMO,NBEA,ATP6V1H,KHDRBS3,PNMA2,MSANTD4,MPP6,OGA,HRASLS5,HBS1L,INPP5K,GK,TCERG1,COPS8,GLS,TOX3,TNRC6A,ZNF638,DCLK2,GOLGB1,GPM6B,FUT10,DIDO1,GRIN2C,GRM5,GRM7,ZNF496,CIT,PTPN5,GSTT2,LINGO1,MAEL,HAS2,HPS5,MAN1B1,ARHGAP19,TLX1,OPALIN,MSL1,C5orf24,IGSF1,ZNF678,LRRTM3,ITGAV,JAK1,METTL21A,OLFM3,KCNC1,KCNN2,KLC1,IPO5,TTYH2,LIMS1,HECTD2,ZFYVE27,MAP6,MAT2A,MBNL1,MEIS1,SRSF12,MEST,MID1,ERICH3,RSPO2,MXI1,MYCN,RTL5,NAP1L3,NCAM1,NCAM2,SLC11A2,HCN1,SETD4,OCRL,GPR88,OGG1,OLR1,LOC100128398,GPR137C,PAH,PAK3,CNTN3,PCDH8,PRTG,PDE4A,PDE4D,FAM98B,CDK14,HERC2P3,ANLN,FAM216A,PLP1,C11orf49,PPP2R5E,PPP3CA,PPP3CB,KANSL1,PKIA,PKN2,HYDIN,WBP1L,SIDT1,CNTLN,PLPPR1,PTHLH,PTK2,PTN,TMEM260,PTPN13,EML5,PTPRO,RAB5B,ZNF793,DBX2,RBBP6,MSANTD2,SLC6A15,ZYG11B,RFX3,RFX4,RGS3,RGS7,SEC61A2,RNASEL,CARF,ROBO1,ELP2,TMEM100,FBXW7,ACER3,ATAT1,KCNIP1,RTN1,RYR3,DGLUCY,SALL1,ATXN7,LRFN5,HOGA1,FAM19A1,SCP2,TNFRSF19,HSPA4L,SH3GL3,FERMT1,CPEB3,MAGI3,CHD9,FBXO11,FHOD3,NLGN1,SLA,ZNF365,BTBD3,DHX30,SEPHS1,ARHGEF40,EFHD1,GKAP1,SORCS3,DMRTC1,CDK5RAP2,RIMS1,ZNF415,FAM126B,SPP1,ERC1,ZBTB43,NPAS3,C11orf87,CLASP2,ITPRID2,MESP1,SAMSN1,ZC4H2,SS18,ELOVL4,SEPT8,ARHGEF9,PLCB1,SYT1,DDHD2,CAMSAP2,FBXW11,TCF4,SATB2,TCF12,SYNE1,RALYL,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,ZFPM2,AP4E1,THRA,GZF1,HEY1,BHLHB9,ZFP91,TMPO,RIMBP2,TPM1,TPM3,TPM4,ZNF384,PRMT8,PDSS1,AMACR,ZKSCAN5,GORASP1,PLEKHH2,VLDLR,TBC1D15,LAT2,CLDND1,SLC47A2,ZNF74,WNK1,CA10,PCDH15,FIP1L1,FAM47E,RTN4,PHTF2,ADAMTSL3,JMJD1C,FRMD6,DPF3,SLC4A10" MicroRNA hsa-miR-26a:mirSVR_lowEffct hsa-miR-26a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-145 1.07E-141 3.71E-144 3.42E-143 414 1911 "KCNH8,ARID1A,KLHL32,AXIN2,SORCS1,RNF150,ADRB2,DPY19L2P4,NLGN4X,SLC44A5,MTUS1,KCTD16,KIAA1324,LRRC7,SPARCL1,ABCD2,ARHGAP20,PCDH10,FAM135A,SYT13,AMPH,AMT,OGT,ANK2,PPFIA1,PKP4,EPB41L5,GPAM,ALS2,API5,USP37,APP,LGR5,PPP4R4,CASK,ARHGAP5,NUMB,ATM,NOL4,MYOM1,DOCK11,SEC11C,BCL2L2,NRP2,CDK5R1,CACNA1G,NIPA1,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,CASC2,CHRNB2,SLIT2,RAB28,PPT2,C4orf33,NIPBL,CNTFR,AKAP6,COL9A1,LETMD1,AKAP5,SLC4A8,AHCTF1,CP,CPS1,PREPL,CREM,AKAP12,ANKRD44,SUSD5,ATRNL1,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,GPSM1,EDRF1,CCDC144A,CYBB,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,TOX,LIN54,MATR3,DGKB,PABPC5,DBI,DNAL1,ARMCX4,ARMCX2,YTHDC1,C8orf34,ZBTB24,ELMO1,KIAA0753,KLHL3,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RABGAP1L,RAB39B,DYNC1I1,CPEB2,DOCK2,DRP2,ECM2,MAMLD1,GOLT1B,E2F5,AASDH,EDIL3,EDN3,EDNRB,CNNM1,RBM12,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,EML1,C8orf37,DCTN4,USPL1,SEZ6,ENPP6,CDKL3,EYA1,F5,F8,FAM198B,AMZ2,ACSL4,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,POLK,UBE2E3,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,PHYHIPL,ZMAT1,GABRB3,GABRG1,HBS1L,BRPF3,FAM120B,NCKAP1,IQGAP2,GATM,IGSF5,FAXC,MSTN,NFU1,MALT1,SPIN1,GLI2,PCDH11X,FERMT2,GPM6B,GPR12,NUDT21,GPR37,TMEM121B,CECR2,PCLO,RAPGEF4,PLCD4,GRIK2,ATE1,TMEM25,ZBTB45,PSIP1,GUCY1A1,RASSF8,C1orf94,DDX19B,ARHGAP36,ELOVL5,SCRG1,HNMT,HNRNPK,HSP90AA1,SMAP1,IGF1,IGFBP1,DOCK7,SCIN,IL11RA,IL12A,ZNF678,INPP5B,ZNF385B,ITGAV,SLC35G1,METTL21A,KCNB1,KCNH1,KIF5C,IPO5,CYP27C1,LRRC4B,STMN1,HECTD2,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,MOBP,SAMD5,MSI1,MSRA,MT1M,CTNNA3,LAYN,NAP1L3,NCAM2,NEFH,NEUROD1,NOVA1,SMIM11A,OPCML,OPHN1,KCNK10,CNTN3,PCDHGC3,PCMT1,PCSK5,PDE4B,PDGFRA,PDYN,PENK,PFKFB2,GDAP1L1,PIK3CD,A2ML1,FAM216A,SCHIP1,SH3KBP1,CCDC144B,PPP2R2B,LRRN3,PPP2R5E,RASGEF1B,PRKACB,RELN,CNTLN,PTCH1,ANKHD1,UHRF1BP1,BDNF-AS,PTK2,TMEM260,PTPRB,OCIAD1,EML5,PTPRE,PTPRH,PEX2,ZSCAN2,TUG1,PID1,ACSS3,ATG16L1,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,RET,REV3L,GTDC1,SEC61A2,LGI2,CCDC82,EXD2,C12orf49,ALG9,RPE65,SNX22,PRR5L,ACER3,RPS6KA2,KCNIP3,YJEFN3,RYR3,ATXN2,FAM19A1,TNFRSF19,SELL,ASRGL1,SUPT20H,ITSN1,FERMT1,NTNG1,MAGI3,FNDC3A,SLITRK3,CNKSR2,ST3GAL3,NUBPL,PPP4R3A,LRRC55,SLC6A8,SHANK2,SLC12A2,SLIT1,SMARCE1,SNRPN,FAM126B,UNC80,TRERF1,SOX2,KIF21B,BDP1,KDM4C,ERC1,PEG10,RBM26,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,FGD4,ADAMTS17,SYN1,COBL,DDHD2,CAMTA1,ALG1,ANO4,DMXL2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,PSD3,GPRIN3,TEX15,SIRT1,ZFPM2,ITGB3BP,ZNF106,HHIP,AKTIP,SLC44A1,GZF1,TLR4,SEZ6L,TPD52,NPL,RGMB,SYNPO2,TRIO,CLHC1,TMEFF2,FLRT2,USP1,VAV2,WIPF1,NSD2,XPO1,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,URM1,KCNAB1,CAB39L,SLC17A6,MVB12B,DOCK8,PHTF2,FBXO36,ACTR3B,SSPN,NETO1,CPNE4" MicroRNA hsa-miR-1909:mirSVR_lowEffct hsa-miR-1909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-145 1.07E-141 3.71E-144 3.42E-143 414 1911 "VWA5B2,TTYH1,ASIC1,ACHE,SYS1,ADARB2,GALNT16,RNF157,ERMN,PLEKHH1,GRAMD1B,AP2A2,PCDH19,KCTD16,PLA2G6,CARNS1,GPRASP2,MRTFA,PDZD4,AMPD2,SEMA7A,FGD2,PHF12,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBB1,LGR5,AQP6,KIAA1614,SEMA4G,MADD,ARHGDIG,ASCL1,CCAR2,TMEM108,ATP1A3,MPDZ,BCL2L2,MIR9-3HG,CFLAR,LDHD,KSR1,SYNJ2,CACNA1I,WASF1,BAIAP3,MMD2,CACNA1D,CACNA2D1,CACNG1,LURAP1,CALB2,DIRAS1,KALRN,HAP1,CAMK2G,CANX,CBLN1,KYAT1,CD81,ARHGEF2,KCNAB3,LRRFIP1,LGI1,NOG,CRLF1,SRSF11,CHRM1,PLEKHB1,CHRNA4,TAOK2,DLGAP3,EPS15L1,NRXN3,CLTA,IGLON5,ARMC8,TOGARAM2,HS3ST5,ZNF385A,PNKD,RBM39,GDA,TRIM69,CSF1,SEC24C,LRIG1,PLCH2,PITPNM3,PNPLA8,PUM1,ST18,RUBCN,GAPVD1,EARS2,PITPNC1,DCTN1,B3GAT3,MFAP3L,FBXO25,SMG7,PARD6A,WDR20,DLG4,CD99L2,SLC29A4,TRAPPC9,ATN1,ARRDC4,DTNB,FIS1,EDN1,FCF1,TMTC1,CACNG7,CELSR3,PHF20L1,EGFR,TMEM132E,RASA4,EIF4G1,ELAVL3,MRNIP,EIF1,OLIG2,EPB41L2,DMTN,EPHB1,ENPP6,ANKRD13B,SLC43A2,EFS,CEP85L,SPEG,MRPL10,PIPOX,RTN3,ANKMY1,CEND1,SIRPB1,F5,TUBB4A,TAOK3,RACK1,FCGR1B,TOMM40L,KAT8,PPP1R1B,POLR1B,FGF11,SPSB4,CAMSAP1,EVL,NOP56,SYT3,AK8,PDLIM5,ADGRA1,DKK3,GABBR1,HRASLS5,GALNT15,B4GALNT1,GHDC,NCKAP1,SIGLEC8,C15orf41,LRRC37A6P,TUBGCP4,SRCAP,CYP46A1,AHDC1,USP19,HEPN1,MALT1,RUNDC3A,GLYR1,STARD3,KDM2B,KCNMB4,GNAO1,LILRB4,PRUNE2,MCHR1,GRB10,GRIA1,GRIA4,GRM7,LINC01089,GSN,KAT7,LINGO1,GUCY1B1,SLC2A6,UBE2QL1,MAN1B1,HRH3,DDX19B,ATXN2L,HPSE2,HMGCL,HNF4G,HPCA,HSP90AA1,FAM95B1,MYLK2,IGF1,C5orf24,RBPJ,TJAP1,IGSF1,IL6R,SCRT2,IL11RA,C2CD4C,KCNC2,GPR62,KCNJ3,KCNJ10,KCNK3,LINC00634,A1BG-AS1,STXBP5,TTYH2,CAMK2N2,PAXBP1,LSS,MAOB,MAP4,MARK3,MDM4,SCAMP5,MOV10,MPP2,ERICH3,GIT1,MSI1,NRBP2,MT3,MYO7A,RTL5,BEX5,FXYD7,P2RY13,DNHD1,NRGN,SMIM11A,NTRK3,GPR88,ZNF827,CDK18,PDE4A,PIRT,CAMKV,KCTD15,PLEC,ASPDH,MTRF1L,PLXNB3,EXOSC10,FA2H,POLR2F,TMEM235,MED1,PPP2R5C,VSTM2L,PRKAR1B,MASP1,NDUFS7,BCAS3,SIDT1,UHRF1BP1,ELOVL2,RAB3A,SLC25A48,FAT4,RAP1GAP,FEZF2,KCTD17,RNASEL,ELP2,MRAP2,SGSM1,ADAL,MAP6D1,SOX8,ATAT1,STX1B,FAM192A,DGLUCY,FOXRED2,MAPK12,SARS,HOGA1,SCP2,ASIC4,SEC14L1,TRIM46,SELL,CASC3,KIF21A,ITSN1,ARX,R3HDM2,ZNF365,URGCP,PPP4R3A,SMTN,KANSL3,SLC6A8,YPEL4,RAB3GAP1,BTBD7,LGI3,ARFGAP1,SMARCD3,MYH15,RCOR3,IGSF9B,RIMS1,KIF13A,KDM4B,ZCCHC24,SOX10,SP2,ZSWIM8,LHFPL4,DBNDD2,LHPP,TAB2,COLGALT2,SSTR1,NCDN,MAPK8IP3,SEPT8,STAC2,ADHFE1,PHLDB1,STXBP1,FAM168A,FGD4,VAMP1,RHBDL3,ARC,SYP,TACR1,KAZN,CAMTA1,MCF2L,EXOC7,PDLIM2,WWC1,VWA3A,NEU4,TPCN2,RPGRIP1L,SZT2,DOCK9,SIK3,RNF216P1,LEFTY2,MTMR14,TIMP4,RELL2,RIMBP2,TP53BP1,RBFOX2,SEZ6L,NPL,STXBP4,TRPM2,PPIL6,NTSR2,RUSC1,KCNE5,HIRA,CADM1,CLEC2L,UBTF,OSBP2,FLRT2,MGAT5B,PLPPR2,BEST1,VSNL1,LAT2,GUSBP1,SLC13A3,XRCC4,PCDH20,ZNF70,DPYSL5,PCBP1-AS1,WNK1,PMEPA1,MAP3K12,RGMA,EVI5,GDPD5,XKR7,CIAPIN1,ITM2C,RGS7BP,UBE3B,TMEM63C,TRAM2-AS1,TIGD6,VANGL2,TTC7A,LAS1L,SPATA13,JPH3" MicroRNA hsa-miR-664*:mirSVR_lowEffct hsa-miR-664*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-145 1.31E-141 4.54E-144 4.18E-143 398 1772 "ABR,ASPHD1,CLK4,GALNT16,BRAP,SORCS1,PTCHD1,ZNF608,SNX32,TBC1D14,OSBPL6,CC2D2A,TAOK1,SRPX,UNC79,DPP10,ANK3,EP400,LCORL,PPFIA1,CNTNAP1,EPB41L5,PHYHD1,BCAS1,MIER1,ARNTL,PLA2G4C,CADPS,ASPA,DACT3,PCDHGB4,NUMB,ATP1A2,SLC4A4,ATP2B1,ZNF582,SLC2A11,BCL2L2,KSR1,BMPR1B,CASTOR3,AP1M1,RAB29,DDR1,CACNB2,CACNG1,PTBP2,CAMK2G,TRIM41,METTL6,INA,SLC16A4,TMEM257,ZBED1,DCLK1,L3MBTL4,DIS3L,CFL2,FOXN3,PLEKHB1,KMT2C,CPNE6,CLTA,FBXO7,IGLON5,COL9A2,MFSD4A,SLC35F1,SEC31B,CLOCK,HINFP,GDA,CLIP3,SNCAIP,SEC24C,ARHGEF10,CSNK1G3,SUSD5,NCAN,PDE4DIP,KIAA0040,GREB1,SEC14L5,KATNAL2,RIPOR2,KIAA0513,ZNF337,TM9SF4,LIN54,TMEM170A,SCRN1,SPOCK2,ARMCX4,C8orf34,ZEB2,HP1BP3,RUSC2,GUCD1,POM121,NTM,RABGAP1L,DMTF1,DTNA,MAMLD1,DNM1L,EDNRA,ATL1,HIPK3,HEYL,TMTC1,SUGP2,KMT5B,AASS,EIF5,IRAK4,TENM1,ELAVL4,TUBD1,ENPP6,DENND4A,IGSF6,ZNF549,DNAJC27,EZH1,ABCA8,FAM198B,PTK2B,DLC1,ZMYND10,GORAB,FECH,FER,GTF2IRD2,OLFM1,SPSB4,FGR,AMOTL2,PCYOX1,VTI1B,PSD2,SLC37A3,COQ5,SORBS1,APOPT1,CAMKK2,KHDRBS3,DACH2,FYB1,DKK3,FAM120B,ZMYND11,B4GALNT1,ZNF274,MTHFD2,ATP8A2,SRCAP,SULT1C4,GGT7,GHR,HPGDS,GLYR1,TNRC6A,MSL3,GLUL,MAP7D2,DCLK2,GNAL,GOLGB1,GPD2,GPM6B,PRLHR,LPAR4,NUDT21,PCLO,PLCD4,SPACA9,ADAMTS13,CACFD1,GRM5,PTPRT,ZBTB49,AP4S1,FAM107A,ADAMTS6,RASSF8,PTGDR2,TNFAIP8L3,MIER3,SYNPO,HMGCL,ZDHHC15,HSD17B1,ATCAY,MSL1,LRRCC1,USP54,IL11RA,INPP5B,INSM1,LRRTM3,JAK2,SLC35G1,KCND1,KCNJ5,KCNJ10,KIF5C,KIFC3,STXBP5,LIFR,LIMS1,PAXBP1,PIK3AP1,GPR155,MAP2,LYPLAL1,SYT9,LRP1B,KCTD6,MID1,POC1B,MOG,CD200,CPNE9,COMMD5,BCO1,RSPO2,PABPC1L2A,NAP1L1,NCF2,SLC11A2,NTRK2,NUCB2,OMG,LOC100128398,DPY19L2P2,PCDHGC3,PCDH9,PDE1A,PDE2A,CCSER2,GPSM2,PRIMPOL,CDIP1,MBOAT7,SLC36A4,TNPO2,FAT3,POU6F1,PPARA,PPM1B,TATDN3,PPP2R2C,LRRN3,PTPA,PPP2R5C,PRKAB2,PKN2,GON4L,MTMR10,ELOVL2,ZSCAN32,ZSCAN2,TUG1,RALGDS,RAP1GDS1,HKR1,ZDHHC14,BSDC1,UBR7,TTLL7,MRPS18A,RIC8B,PBRM1,RNH1,PNMA8A,GSTCD,ROBO1,ROBO2,CCDC102B,RPL15,ACER3,CLIP1,FOXRED2,SALL1,MAPK12,MIR124-2HG,PRCD,FNIP1,TNFRSF19,TRIM46,GALNT10,SH3GL3,DOCK10,FBXO11,ST6GAL1,CTXN2,SLC1A3,FAM81A,SLC6A11,SEPHS1,SLC8A3,CDK5RAP3,CCDC88A,SLC11A1,SHANK2,KBTBD4,NAPB,SLC15A2,ELMO2,BTBD7,SMARCA4,MYH15,SMARCE1,LIMCH1,MBD5,CABCOCO1,SNRPN,BDP1,KIF1B,CDK19,MCF2L2,COLGALT2,ZC4H2,INKA2,SEPT8,STAC2,KANK1,SYT11,JMJD6,RHBDL3,VPS13A,ADAMTS17,SYN2,COBL,ANKRD28,SLC37A2,TACC1,TAF6,EXOC7,KIAA1107,ATMIN,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,FAM189A1,PCDHB9,ATP13A2,SIRT1,CRB1,TMEM9,TK2,TLL2,TNS1,PRMT8,TRPS1,RUSC1,PITPNB,FLRT2,PLEKHH2,USP1,BCL2L13,VIPR2,PCDH20,FMN2,UPF3A,CA10,CADM2,PRDM2,LINC02210,PRDM10,RNF103,HPS4,PCDH15,GAL3ST3,SNX27,WIPF2,MPPE1,FZD3,CASC15,NLRP3,TRAM2-AS1,RNF170,IFT88,RNF146,ST8SIA2,JPH3" MicroRNA hsa-miR-3176:mirSVR_lowEffct hsa-miR-3176:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.65E-145 3.17E-141 1.09E-143 1.01E-142 402 1811 "SDE2,ACADM,EMILIN3,FAM43B,GALNT16,TMCC3,PNMA8B,PLEKHH1,GRAMD1B,PWWP2A,RNF150,PTCHD1,SLC24A4,MTUS1,AGT,RTL9,TBC1D14,WDR35,TXNDC16,CC2D2A,HFM1,TAOK1,ALAD,CEP126,SYT13,FGD2,MYH7B,SMIM29,PPFIA4,PHF12,SUGT1P4-STRA6LP-CCDC180,APBB1,VAT1L,MIER1,SEMA4G,ARNTL,PLA2G4C,STK33,MARK4,DACT3,NCOA1,RASL11B,ALDH4A1,STX16,ALDH7A1,N4BP2L1,TTLL9,ADAM15,BACH1,ADGRB1,BCL2L2,ZNF599,SYNJ2,ARHGEF7,CACNA1G,GPC2,MMD2,DDR1,CACNB2,CAMK2D,CAMK2G,TRIM41,SLC25A14,CLDN10,METTL6,P2RX6,ZBED1,NOG,UBE2L6,SRSF11,SOCS6,KMT2C,CLCN4,FBXO7,SRP14-AS1,MAP4K4,ARHGEF6,AKAP6,TCEAL2,NECTIN3,CDC42BPB,SH2B1,ANKRD44,C1QL2,SNCAIP,CSF1,CSF2RA,ARHGEF10,CSNK1E,PPP1R16B,CMTM5,CFAP61,CTNND1,NRSN1,DCAF4,ARHGAP32,GAPVD1,RIPOR2,ARHGAP24,DCAF8,FRMPD4,CENPL,ZNF337,TBC1D5,MATR3,IST1,DBN1,ELMO1,KIAA0753,RUSC2,COPS7A,RHOBTB1,SRGAP3,KIF19,SEC16A,ZNF582-AS1,CDON,FAM57B,DTNB,TOM1,ABCC5,EDN1,SGK2,FCF1,HEYL,KLHL5,RBM12,EGFR,TENM1,HSD17B14,EPB41,EPHB1,SLC43A2,ETV1,PIPOX,F5,NSRP1,FAM198B,TBC1D16,PTK2B,TOMM40L,FKTN,STRADA,PRMT5,BAIAP2,PRKAG2,IP6K2,SYNCRIP,AGAP3,RGPD5,PSD2,WDR83,APOPT1,ATP2C1,ST6GALNAC3,B3GAT1,TMEM151A,FYN,SDCBP2,GABBR1,TRAF3IP2,FAM184B,DENND2A,B4GALNT1,RAPGEF6,IP6K3,MTHFD2,DISC1,INPP5K,GART,ALDH1L1,ARFIP1,MALT1,DHRS4,TCERG1,GLYR1,STARD3,LOXL3,GNAS,PRRC2B,NUDT21,TMEM121B,GRIA2,GRIA4,GRID1,GRIN2C,FAM19A2,BVES,SLC2A6,ATOH8,HAS2,HPS5,PADI2,PACSIN2,MAN1B1,CPT1C,LRRC75A,SHISA6,FAM95B1,LINC00667,MYLK2,NKD1,USP54,LIX1,INPP5B,ZNF385B,SLC35G1,KCNH1,KCNMA1,KCNN2,GATD1,KLC1,LIFR,SFXN5,SYTL4,SMAD9,ZNF667-AS1,LOC100128239,MAP6,ADAM11,MGAT3,MMP16,MOG,GIT1,SAMD5,MSRA,RSPO2,MXI1,MYH6,RTL5,MYT1,HNRNPM,FXYD6,NBL1,NCAM1,CCDC13,VWA2,DNHD1,SMIM11A,TBC1D25,OGG1,GPR137C,PBX1,PCSK5,PCSK2,BEST3,SEMA5B,TMIE,PIK3CD,NLE1,PLCB2,PNMA3,C11orf49,TRHDE,RETREG2,SLC36A4,PILRA,POLG,NXPH1,MED1,PPM1B,PPP1R1A,TATDN3,PPP2R2C,PPP2R5E,PRKAB2,PRKCZ,CYBC1,GON4L,SNRK,ZIK1,PTPRE,PTX3,TUG1,PLEKHB2,RAP1GAP,ARID4A,MSANTD2,CRTAC1,ZYG11B,TRIM68,ZDHHC4,PRIMA1,ARMC5,CYB561D1,RORB,SNX22,ATP8B4,LRRK2,LGR4,FAM161B,TMEM156,FAM192A,MAPK12,DRAXIN,ATXN2,PRCD,PEAR1,MRAS,ITSN1,SHC4,MAGI3,ST3GAL3,ANKRD6,NUBPL,ZNF365,PEX26,KANSL3,LRRC55,SLC6A7,SLC6A11,ARHGEF40,SIRT2,CCDC88A,SLC11A1,KBTBD4,ELMO2,ANKRD36,SNRPN,PALLD,TMCC1,USP33,SOX3,TNIK,SPATA7,ZSWIM8,ZC3H13,SPTAN1,SPTB,TSPYL2,ATP10B,COLGALT2,ST5,MAPK8IP3,MPRIP,ZSCAN29,DIP2A,PHLDB1,SEPT3,FGD4,ZFR2,RHBDL3,SYN1,SYT1,C12orf76,TAL1,CNTN2,AGTPBP1,IQCE,TMEM136,TBX15,VWA3A,ATMIN,SYNE1,SLC19A3,OBSL1,AKNA,USP32P1,FAM200B,CHST8,C18orf54,ENHO,TMEM9,TK2,TNFRSF1B,PIK3R5,RASD2,NPL,ZNF346,PRMT8,ELP5,AMACR,TRO,TRPS1,ZMYND8,KCNE5,TSC1,TTTY15,SGK3,CCDC14,BEST1,NSD2,SLC13A3,CELF4,FSTL5,TMEM198,ZSCAN26,SLC30A4,DNALI1,LMAN2L,NAV3,URM1,LINC00632,PCBP4,MARCH8,FAM219B,ZNF248,MSRB3,NETO2,AP3B2,GAN,JPH3" MicroRNA hsa-miR-3125:mirSVR_highEffct hsa-miR-3125:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.70E-145 3.77E-141 1.29E-143 1.19E-142 393 1734 "TTYH1,SDE2,KCNH8,ARID1A,CSMD3,GALNT16,ADCY2,SLITRK1,SORCS1,ERMN,ESYT2,ADRB2,MTA3,SLC44A5,RTL9,OSBPL6,CC2D2A,ADGRF5,SRPX,FAM135A,KCNT1,OGT,ANK2,MYH7B,PARG,APC,UPRT,DDO,FAM131A,API5,MIER1,SPTBN4,ASPH,RASL11B,ASTN1,CADM3,N4BP2L1,BARD1,NRP2,ZNF599,KSR1,NAE1,JAZF1,THSD7A,KALRN,PTBP2,SLC25A14,HIP1R,NFS1,PRC1,CBR1,CBS,KRIT1,CERS5,USP6,MTMR7,TMEM257,CDC42,ZMYM4,CDO1,TIGD7,RCBTB2,CHGA,CHI3L2,PLEKHB1,SYNPR,NRXN3,PPT2,CLCN3,KIAA1549L,C4orf33,CNR1,PCYT1B,AKAP6,BTF3L4,LETMD1,SMARCAL1,ACBD5,SLC35F1,CRMP1,RNF14,HINFP,ANKRD44,GDA,SNCAIP,SLITRK5,CMTM5,RIMS2,RUBCN,CX3CR1,CYBB,FGFR1OP2,RIPOR2,ARHGAP24,DGKB,PITPNC1,ZEB2,KIAA0753,COPS7A,MED24,GSDME,SMG7,FAM107B,KBTBD11,CHRDL1,DMD,USP3,DNAH9,MED12,CDON,DNM2,ACOT8,RCAN1,GNE,FAM78B,DUSP9,DNAJB6,ABCC9,E2F5,EBF1,FCF1,FSD1L,YAF2,EFNB3,PHF20L1,SUGP2,SORBS3,ING4,RGS17,OLIG2,EPB41L1,EPHA5,SIRPB1,EXTL2,F8,ARMCX1,CLVS1,FABP7,CACNG3,ZIC4,ZSCAN30,FGF12,FGF14,FGFR1,FHL1,CAP2,FOXM1,ATP13A4,SORBS1,FAM49B,STAMBP,ATP6V1H,ERGIC3,DLL3,MSANTD4,TPPP3,OGA,STAG2,GABRB1,GABRG2,AHCYL1,ARPP21,GALR1,GAP43,ZNF559,C15orf41,DISC1,GATM,SRCAP,SULT1C4,GLDC,GLS,KDM2B,ZNF782,FUT10,LILRA1,RAPGEF4,GRM7,GRM8,KIF3A,LINC00839,RNF165,MFSD2A,RABL2A,MIER3,HMGB1,GABARAPL2,HNRNPK,ZDHHC15,TCEAL6,SHISA6,HSP90AA1,SMAP1,HTR2A,RBPJ,IGSF1,IL11RA,INPP1,LRRTM3,NME9,JAK1,KCNJ16,KCNK2,KIT,STXBP5,INSYN2,VWA5A,HECTD2,NCOA7,MAOB,LRP1B,MEIS1,MMP16,MN1,SESN3,FXYD7,SFR1,NELL2,NEUROD1,NEUROD2,NF1,NRCAM,SETD4,GLIPR1L2,PAK3,CNTN3,PCDH9,PCSK1,PDE1C,PDE4B,PDYN,BEST3,ZNF655,PLCB2,ST8SIA5,PLP1,PCDH18,PURG,MAPKAP1,SCHIP1,EPB41L4B,NXPH1,MED1,PPP2R5C,PPP3CB,PKN2,EPDR1,DIRAS2,SAMD9,SLC22A23,GON4L,MDGA2,CNTLN,PTCH1,MTMR10,PXK,PTPRE,PTPRZ1,TTC13,ZNF615,MARCH1,CEP97,RAD51D,NWD1,RASGRF1,RASGRF2,ARID4A,RADX,RET,REV3L,RGS7,RGS10,TTLL7,MRPS18A,RNASEL,TMLHE,EXD2,ALG9,CARF,ROBO1,CCDC102B,RPE65,KIAA0895L,ZNF671,ATP8B4,SGSM1,MEG3,ABCA11P,SOX8,KCNIP1,RXRG,NCBP3,AP1AR,AMER2,SATB1,LRRTM4,ELMOD1,CASC3,ASRGL1,SH3GL3,KIF16B,SHC4,SLA,ZNF365,SLC1A3,FAM81A,PPP4R3A,RUFY2,KDM4D,SLC8A3,ARHGEF40,SLC11A1,ATF7IP,MYH15,TTC17,CMTR2,LMBRD1,SON,TNIK,SP4,HECW1,KDM4C,UNC5B,PEG10,KIF1B,NPAS3,C11orf87,TAB2,TROVE2,CLSTN2,STOX1,SSTR1,ZC4H2,GANAB,SEPT3,FGD4,SYNE2,ASTN2,ADGRL3,KLHL4,ANO4,DMXL2,SATB2,RPGRIP1L,SYNE1,SLC19A3,PCDHAC2,PUM2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,CRB1,LEFTY2,ZMAT3,ASXL3,TLL2,BHLHB9,HEY2,ZNF384,PRMT8,ZMYND8,DCBLD1,RFTN2,SGK3,MGAT5B,VAV1,WIPF1,CLDND1,RICTOR,XRCC4,SF1,ELFN1,GPR158-AS1,NDRG4,SPHK2,REEP1,PLPPR5,SMARCAD1,PMEPA1,PRTFDC1,SCG2,NAV3,C12orf4,FAM13C,PHTF2,RNF170,DPF3" MicroRNA hsa-miR-137:TargetScan hsa-miR-137 TargetScan 9.04E-145 5.08E-141 1.74E-143 1.60E-142 291 943 "ABHD6,NCKAP5,ACTN2,CSMD3,FMNL2,ELFN2,ADCY2,DSCAML1,RNF157,PWWP2A,RNF150,BEND6,NLGN4X,INTS2,MTUS1,GPR158,HECW2,OSBPL8,PITPNM2,CDC42BPA,ANXA7,GPAM,ARHGAP5,CADPS,ASPH,NCOA1,INSYN2B,ATP2A2,ATP2B2,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CACNA1I,CACNA1G,NIPA1,BSN,LDLRAD4,FOXK1,CACNA1D,CACNB2,DIRAS1,CAMK2A,HIP1R,CBFA2T2,REPS2,CDC42,KCNAB3,L3MBTL4,CLGN,CFL2,FOXN3,CHGA,CHM,NRXN3,NRXN1,FAM19A5,DNAJB5,QKI,NIPBL,IGLON5,BAG4,NRG2,C2CD2,CREB5,ANKRD44,OSBPL3,CSNK1G3,RIMS4,PPP1R16B,GREB1,PPP6R2,PYGO1,DCAF8,LIN54,RIMS3,MAML1,DGKG,DNAL1,DBN1,JAKMIP2,KLHL3,RHOBTB1,CALN1,PDCD6IP,DYRK1A,ABCC9,E2F6,EDIL3,FAM135B,FRY,EFNA2,EFNA3,RBM12,EGFR,MBNL2,EIF4G2,ELAVL3,EIF1,EN2,RCAN2,EPHA5,KCNMB2,EPS8,ERBB4,CEP85L,CEND1,FGF11,NBEA,CAMKK2,NSG1,FUT9,NRG3,MPP6,MEGF11,GABRA1,FAM184B,GAD2,AHCYL1,CPLX1,CSDC2,PPARGC1A,KIAA1958,LUZP2,DCLK2,GPD2,GPR22,GPR26,GRIA1,GRIK3,CACFD1,NR3C1,GRM2,GRM5,GRM7,RNF165,PTPN5,IL1RAPL1,GUCY1A2,ATOH8,RASSF8,KLF12,BACH2,MIER3,HLF,HAPLN2,NEGR1,RBPJ,PLD5,SCRT2,C2CD4C,KCNA1,KCNA2,CDH20,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCNH1,KCNJ3,KIT,LIFR,PAXBP1,NAT8L,MARK1,MARK3,CHIC1,MEIS1,MITF,MSI1,CTNNA3,FXYD6,RCOR2,NEFH,NEUROD1,NEUROD2,NF1,NFIA,NFIX,NOVA1,NOVA2,GPR88,OPCML,CLDN11,GPR137C,PAK3,CNTN3,PDE3A,PDE4A,PDE4D,PDE1B,PDGFRA,HMGCLL1,LRP12,FAT3,MED1,LRRN3,PPP2R5C,PPP5C,PRKAB2,PKN2,MAPK8,MAPK10,FITM2,DIRAS2,PROX1,DCHS2,ELOVL2,PTN,PTPRD,NKAIN1,PLEKHB2,OXR1,RASGRF1,MSANTD2,GTDC1,RIC8B,RAVER2,RORB,RPL15,FBXW7,RIMKLA,RYR3,AMER2,ATXN1,ATXN7,SCN2A,SCN8A,FNIP1,PPP1R9A,PPM1E,CPEB3,CHD9,FAM81A,LGI3,CXXC4,ABTB1,LIMCH1,MBD5,FAM126B,PDZD2,MYT1L,BDP1,CDK19,NPAS3,NFASC,C11orf87,CLASP2,LRRC4,NXT2,FAM168A,MLC1,FGD4,PLCB1,ANKRD28,ATP11A,ANKRD12,MGRN1,ANO4,ACSL6,SATB2,RPGRIP1L,GPRIN3,AHCYL2,ENHO,NACC2,RELL2,HEY2,CSMD1,DOK6,FNDC5,FRRS1L,OSBP2,BCL2L13,MGAT5B,RICTOR,EML6,PMEPA1,CADM2,FAM47E,RGS7BP,MARCH8,HNRNPA3,PHTF2,MSRB3,FRMD6,NETO1,GAN,PRRT4" MicroRNA hsa-miR-1297:mirSVR_lowEffct hsa-miR-1297:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-144 6.84E-141 2.34E-143 2.15E-142 398 1780 "SDE2,KCNH8,ARID1A,KLHL32,AXIN2,ERMN,RNF150,ADRB2,DPY19L2P4,NLGN4X,SLC44A5,MTUS1,KCTD16,LRRC7,SPARCL1,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,AMPH,AMT,OGT,PPFIA4,PPFIA1,PKP4,EPB41L5,GPAM,ALS2,USP37,APP,LGR5,PPP4R4,ASPH,ATM,NOL4,MYOM1,DOCK11,SEC11C,NRP2,CDK5R1,MTMR2,CACNA1G,NIPA1,CACNB4,THSD7A,CALM1,SPAG9,CBS,METTL6,MTMR7,DGKI,CDH2,CCPG1,NUMBL,RCBTB2,CHRNB2,SLIT2,RAB28,PPT2,C4orf33,NIPBL,CNTFR,AKAP6,COL9A1,AKAP5,SLC4A8,AHCTF1,CP,CPS1,FAM171B,PREPL,CREM,ANKRD44,SUSD5,ATRNL1,SOCS5,PDE4DIP,SLITRK5,PLCXD3,PUM1,RIMS2,GPSM1,EDRF1,CCDC144A,KIAA0408,GAPVD1,RIPOR2,ARHGAP24,TOX,LIN54,MATR3,DGKB,PABPC5,DNAL1,ARMCX4,C8orf34,ZBTB24,KIAA0753,LYPD1,DDX46,ALKBH8,POM121,SPOCK3,RABGAP1L,RAB39B,DYNC1I1,CPEB2,DOCK2,ECM2,MAMLD1,DYRK1A,GOLT1B,AASDH,EDNRB,YAF2,PHF20L1,SUGP2,MBNL2,ASB3,KCTD3,EML1,C8orf37,DCTN4,USPL1,SEZ6,GPHN,CDKL3,F5,F8,AMZ2,ACSL4,EFEMP1,DLC1,RACK1,FCGR1B,FKTN,ZNF589,SEC24B,GTF2IRD2,FGF13,PRKAG2,POLK,UBE2E3,IP6K2,SYNCRIP,ZMYND15,FAM49B,ATP6V1H,ATP2C1,CELF1,ST6GALNAC3,PHYHIPL,ZMAT1,GABRB3,GABRG1,BRPF3,FAM120B,NCKAP1,IQGAP2,GATM,IGSF5,FAXC,MSTN,NFU1,PCDH17,MALT1,TCERG1,SPIN1,GLI2,PCDH11X,FERMT2,GPM6B,PRLHR,GPR12,GPR22,NUDT21,GPR37,CECR2,PCLO,GRIA2,GRIK2,ATE1,TMEM25,ZBTB45,PSIP1,GUCY1A1,C1orf94,DDX19B,ARHGAP36,ELOVL5,SCRG1,HNMT,HNRNPK,HSPA1L,SMAP1,MSL1,IGF1,IGFBP1,DOCK7,SCIN,IL11RA,IL12A,ZNF678,INPP5B,ZNF385B,JAK2,SLC35G1,METTL21A,KCNB1,KCNH1,KIF5C,IPO5,STXBP5,KTN1,LRRC4B,STMN1,GPR155,MBNL1,CHIC1,TM6SF1,MEIS2,MOBP,SAMD5,MSI1,MSRA,MT1M,CTNNA3,LAYN,NAP1L3,NEFH,NEUROD1,NOVA1,SMIM11A,OPCML,OPHN1,KCNK10,CNTN3,PCDHGC3,PCMT1,PDE4B,PDE4D,PDGFRA,PDYN,PENK,PFKFB2,GDAP1L1,PIK3CD,A2ML1,PDZRN4,SCHIP1,RETREG2,SH3KBP1,CCDC144B,PPP2R2B,LRRN3,PPP2R5E,RASGEF1B,PRKACB,RELN,CNTLN,PTCH1,ANKHD1,UHRF1BP1,BDNF-AS,PTK2,TMEM260,PTPRB,OCIAD1,EML5,PTPRE,PTPRH,ZSCAN2,TUG1,PID1,ACSS3,ATG16L1,FAT4,FAM184A,RASGRF2,RBBP6,KHDRBS2,REV3L,ERI2,GTDC1,RNASEL,LGI2,CCDC82,EXD2,C12orf49,ALG9,RPE65,SNX22,PRR5L,ACER3,RPS6KA2,KCNIP3,YJEFN3,RYR3,ATXN2,FAM19A1,TNFRSF19,SELL,ASRGL1,SUPT20H,ITSN1,FERMT1,NTNG1,MAGI3,FNDC3A,SLITRK3,CNKSR2,ST3GAL3,NUBPL,WDR37,PPP4R3A,LRRC55,SLC6A8,SHANK2,SLC12A2,SMARCE1,SNRPN,FAM126B,TRERF1,SOX2,KIF21B,BDP1,KDM4C,ERC1,PEG10,RBM26,TAB2,ITPRID2,SSTR2,ZC4H2,NXT2,NEK4,CEP68,ADHFE1,SEPT3,KLHL7,FGD4,COBL,DDHD2,ALG1,ANO4,DMXL2,TCF7L2,TRIM2,RPGRIP1L,TCF12,SYNE1,PCDHB6,PSD3,TEX15,FAM200B,SIRT1,ZFPM2,ITGB3BP,ZNF106,HHIP,AKTIP,SLC44A1,GZF1,TLR4,SEZ6L,TPD52,NPL,RGMB,SYNPO2,TRIO,TMEFF2,GORASP1,FLRT2,USP1,VAV2,WIPF1,NSD2,XPO1,KCNT2,ZNF154,FSTL5,SMARCAD1,LINC02210,STOX2,TMEM178A,HPS4,URM1,KCNAB1,CAB39L,SLC17A6,MVB12B,DOCK8,FBXO36,ACTR3B,SSPN,NETO1,CPNE4" MicroRNA hsa-miR-206:mirSVR_lowEffct hsa-miR-206:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-144 7.96E-141 2.71E-143 2.49E-142 404 1833 "SYN3,EMILIN3,SYS1,CSMD3,FMNL2,KLHL32,SORCS1,ADORA3,OLMALINC,AP1B1,INTS2,GPR158,SNX32,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,HFM1,PCDH10,UNC79,FAM135A,ZNF687,AMPH,AMT,CDC42BPA,LRCH2,PPFIA2,CACHD1,VAT1L,TNRC6C,SHTN1,LGR5,PPP4R4,PDXK,CASK,TMEFF1,ARNTL,ARSF,CHRD,DYNLL1,RNF182,NOL4,ATP6V0A1,TTLL9,ADGRB3,BCL2L2,BCL7A,SYNJ2,ARHGEF7,SCAPER,MTMR3,GYG2,SGCE,C5,WASF1,MMD2,BTRC,CA12,CACNA1A,CACNB2,CALB1,PTBP2,NGB,SYT6,PRC1,METTL6,ENTPD6,CDH2,SRSF11,CHM,CASC2,LSMEM2,NRXN1,TJP2,QKI,NIPBL,AKAP6,LETMD1,AKAP5,TBPL1,SMARCAL1,CLOCK,CRHBP,AKAP12,ANKRD44,CSF1R,ATRNL1,NCAN,CNTNAP2,SLITRK5,SDC3,KIAA0040,PHF14,ARHGEF4,CTNND1,RIMS2,GPSM1,ARHGAP32,HDAC4,TOX,TBC1D5,AIF1L,PITPNC1,C8orf34,ZBTB24,PLEKHM1,MYEF2,KIAA0319,CEP170,MAGI2,SPOCK3,SV2A,SRGAP3,FAM107B,KIF19,DLG4,HS3ST4,DMPK,HS3ST2,USP3,CDON,DNM2,GNE,DYRK1A,GOLT1B,EBF1,EDIL3,FAM135B,HEYL,KLHL5,TMTC1,YAF2,SH3GLB1,EFNB3,ABI2,KCTD3,EIF4G2,EIF5,PLEKHA1,RGS17,EMX2,EPB41L1,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,CLVS1,FAM198B,WAC,RPS6KC1,SH3YL1,PTK2B,ZIC4,TAOK3,FCGR1A,TESK2,ZNF589,FGF14,FGFR3,BAIAP2,RGPD5,SLC37A3,FLYWCH1,PDLIM5,NPTN,DLL3,TMEM151A,ZNF512,STAG2,GABRA1,GALNT15,ZMYND11,ZNF274,DISC1,CPLX2,MYOZ2,IGSF5,TUBGCP4,MSTN,LYVE1,NTNG2,TOX3,KDM2B,GNAS,GNG4,FUT10,LILRA1,GPR22,GRIA2,GRIK2,NR3C1,PRDM5,GRM7,BTN2A1,GSTM5,ADAMTS6,IRAK3,UBE2QL1,PADI2,KLF12,BACH2,ELOVL5,ACOT7,HNMT,OPALIN,LRRC75A,SMAP1,IRF8,FAM95B1,KNDC1,LRRCC1,IL6ST,BRINP3,INPP5B,ITPKB,KCNMA1,LIFR,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,SYT9,AFF1,MOBP,MOG,GIT1,SAMD5,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM1,NCAM2,NDUFA5,ALDH1L2,VWA2,ZNF827,ZDHHC22,GLIPR1L2,PAX6,PBX1,PRTG,GPR85,CAMKV,FAM218A,PMP22,EPB41L4B,TNPO2,PPP2R2B,PPP2R2C,VSTM2L,RAB39A,SLC22A23,WBP1L,SIDT1,GON4L,CNTLN,PTPRN,ZNF793,FAT4,SUSD4,ZDHHC14,ZYG11B,REV3L,RGS3,RIC8B,ZFHX4,RERGL,CYB561D1,TMEM100,NEK11,ZNF671,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,ATXN2,LRFN5,SCN3A,LINC00461,GALNT10,SFPQ,SUPT20H,SGK1,PPP1R9A,KIF16B,DOCK10,NTNG1,CHD9,FBXO11,ST6GAL1,SYBU,NUBPL,PPP4R3A,SLC6A8,SLC8A2,SLC8A3,SLC9A5,SHANK2,SLC12A2,TMEM132D,SLCO1A2,ZFP1,SMARCA4,SMARCC2,LIMCH1,MAPKBP1,TMCC1,FAM126B,DOP1A,TNIK,SOX10,NMNAT2,CLUAP1,ENKUR,HECW1,KIF1B,NFASC,SRPK2,POGZ,EPB41L3,MPRIP,ELOVL4,KANK1,SEPT3,FAM168A,SUPT5H,SYNE2,VAMP1,C3orf70,SYN1,C12orf76,TAL1,UNC5D,AGTPBP1,SATB2,TCF7L2,TPCN2,SYNE1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,AHCYL2,CCDC173,ZFPM2,CRB1,AP4E1,TGFBR3,TK2,ACTR6,DDHD1,TLR4,BEX4,RIMBP2,CSMD1,KAT6B,TNR,PIK3R5,TPM4,STXBP4,ANKRD20A2,TTTY15,HEPACAM,CADM1,RPRM,SLAIN1,FLRT2,BEST1,VSNL1,RICTOR,GUSBP1,ZIC1,ZNF711,ZNF24,FMN2,MKRN3,ZBTB38,ANKS1B,PLPPR5,UPF3A,PRDM2,LRP8,PCDH15,FIP1L1,WIPF2,ST7,KAT6A,HNRNPA3,ZNF248,RNF170,TTC7A,FXR1,NETO1,ST8SIA2,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-3188:mirSVR_lowEffct hsa-miR-3188:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-144 8.37E-141 2.84E-143 2.61E-142 386 1678 "TTYH1,KCNH8,CSMD3,NDRG3,KLHL32,ADD1,AXIN2,PLEKHH1,USP31,ESYT2,BEND6,HACE1,OSBPL1A,OSBPL8,ADGRF5,BBOX1,AMPD2,USP28,CNTNAP1,UPRT,DGKD,SHTN1,KIAA1614,PDXK,CASK,CADPS,ASPH,ZSCAN18,PCDHGB4,ZBTB10,DDX3Y,ATP1B3,ATP2B2,RIPK1,TTLL9,LINC00847,BCL7A,NRP2,GPR146,SYNJ1,C5,BAIAP3,CFAP410,CA4,CA12,VXN,CAST,MAP7,ZNF501,KYAT1,KRIT1,CERS5,RGN,CD86,ARHGEF2,CHRM1,PLEKHB1,CASC2,LSMEM2,EPS15L1,RAB28,COG1,STOML1,FAM189A2,FAM19A5,DNAJB5,CNGA3,ARHGEF6,IQCK,ARMC8,AKAP6,CABP1,SMARCAL1,BAG4,TOGARAM2,MYRIP,ZNF521,CP,CHD1L,ZNF385A,CREM,RBM39,AKAP12,ANKRD44,TRIM69,CS,CSNK1G3,PDE4DIP,CNTNAP2,ERC2,PLCXD3,CTNND1,CX3CR1,CCDC144A,CYBB,KATNAL2,GAPVD1,ZNF337,RASSF2,TBC1D5,KCTD8,SCRN1,IP6K1,BRINP1,ELMSAN1,ZEB2,CNIH3,HP1BP3,RUSC2,KLHL3,LYPD1,SV2A,SRGAP3,SGSM2,G3BP2,WDR20,FAM107B,ARNT2,EXOG,DMD,DOCK2,DRP2,DTNA,E2F5,USH1C,EDN1,EDN3,EDNRA,EDNRB,SUGP2,EIF4G2,ING4,ELN,PAN3,EPB41L2,RCAN2,SRRM1,PIPOX,VPS26C,DNAJC27,KATNAL1,TMEM132C,FCGRT,TESK2,SCARA3,SYNCRIP,IQCG,C2orf88,FAM49B,KBTBD12,MEGF11,TRAF3IP2,SALL3,GHDC,C15orf41,DISC1,WASF3,ALDH1L1,GCNT2,SRCAP,ARFIP1,GFRA1,GGT7,HEPN1,GLI2,MSL3,GNAL,GNAS,PRUNE2,GPM6B,FUT10,GPR12,STON1,GPR34,GRIA1,PRDM5,BVES,SOX21,ATOH8,FAM222A,MAEL,ZHX1,HRH3,HNMT,NEGR1,CPT1C,SCIN,ITGAV,KCNJ10,KCNJ11,KCNMA1,KCNN3,KIFC3,IPO5,INSYN2,LIG4,FGFBP3,MAN2A2,MBNL1,CHST6,MEIS2,AFF1,MOV10,COL28A1,PTOV1,MTTP,MXI1,MYO6,MYO9A,MYT1,FXYD6,NOVA1,DNHD1,OMG,OPA1,OPRL1,P2RY1,PCDHGC3,CDK18,PDE3B,PDYN,PFKFB3,CAMKV,PIK3CD,SPATA6,FAT3,NXPH1,RASGEF1B,PRKCZ,MAPK10,DIRAS2,GDPD1,MASP1,GON4L,NCR3LG1,ELOVL2,ZIK1,FAM120C,ZSCAN2,NKAIN1,MARCH1,PLEKHB2,RAD51D,RBBP6,ERI2,RFX3,RIC8B,SETD5,C12orf49,ARMC5,CARF,KIRREL1,SNX22,ARMH4,FBXW7,BAALC,ADAL,TCP11L1,MAP6D1,WLS,FOXRED2,SEMA6D,LRFN5,TNFRSF19,CASC3,GALNT10,FAM102A,FERMT1,CHD9,FBXO11,FNDC3A,SEC31A,ZNF365,SLC1A3,SLC1A7,SLC6A11,SLC9A5,SLC12A4,NAXD,MAST1,IGSF9B,RIMS1,ANKFN1,UNC80,RBM34,DOP1A,TNIK,SOX5,KIF21B,BDP1,KDM4C,PEG10,CDK19,RBM26,NPAS3,NFASC,SRPK2,ITPRID2,SSTR2,EPB41L3,INKA2,MAPK8IP3,ZSCAN29,DIP2A,NECAB1,ARHGEF9,VPS13A,PLCB1,SYPL1,SYT4,POPDC3,ANKRD12,ALG1,FBXW11,VWA3A,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,NSD1,USP32P1,AHCYL2,HIF3A,PMS2CL,CRB1,ITGB3BP,TIAM1,TLL2,TMOD1,TNFRSF1B,CSMD1,C5orf64,TNS1,RBFOX2,TPD52L2,ZNF384,SYNPO2,TRO,STXBP4,TRPM2,FNDC5,CA14,SSBP2,PRR18,ZKSCAN5,TUBB1,AMOT,GORASP1,UGT8,FAM181B,MGAT5B,VAV2,WIPF1,SLC13A3,ZIC1,ZNF45,ATP6V0E2,PLPP4,POLR3H,SPIRE1,DHX33,EMSY,PRDM2,DNALI1,SHD,PRDM10,SEMA3B,PPP1R3F,MVB12B,GOPC,KAT6A,CAMK1G,FAM219B,ADAMTSL3,PIANP" MicroRNA hsa-miR-588:mirSVR_lowEffct hsa-miR-588:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-144 9.21E-141 3.11E-143 2.87E-142 389 1704 "RALGAPA1,XKR4,TMEM132B,BRAP,SORCS1,MTA3,GPR158,AGT,KCTD16,OSBPL1A,KIAA1324,BEGAIN,DOC2A,CDC42BPA,DPP10,PI16,PHF12,SUGT1P4-STRA6LP-CCDC180,GPAM,TNRC6C,USP37,AQP4,PDXK,MARK4,CCDC74A,PCDHGB4,SLC2A11,RNF182,N4BP2L1,KSR1,BMP7,SYNJ2,LINC00906,CASTOR3,NIPA1,BAIAP3,DDR1,DIRAS1,MTMR7,P2RX6,ARHGEF2,ASIC3,RAB3C,EPS15L1,RAB26,CNR1,CNTN1,COL9A1,MFSD4A,CRY2,ANKRD44,RGS6,MICAL2,CSNK1G3,ATRNL1,PLCH2,RASGEF1C,ERC2,CTH,CX3CR1,KIAA0408,ARHGAP32,MATR3,DNAL1,ARMCX4,RUSC2,SGSM2,TMCC2,ARNT2,KBTBD11,EXOG,RAB39B,HS3ST4,CD99L2,CPEB2,DOCK2,DPH1,DPP6,DRD1,DTNA,DUSP9,ABCC5,DNM1L,SGK2,TMTC1,ABI2,IRAK4,COPS4,VPS13B,EPHB1,ENPP6,NCALD,TMEM74,ETV1,VPS26C,ANKMY1,PTK2B,CORO2B,STRADA,GTF2IRD2,KIAA1109,FGFR3,FOXG1,IP6K2,PCYOX1,FOXM1,FOXO3,EVL,TMEM175,CAMKK2,CELF1,STAU2,KBTBD12,MSANTD4,NRG3,TVP23A,GABRA3,BRPF3,ZMYND11,RAPGEF6,GALR1,NEK6,GAP43,INPP5K,GATM,GBX2,SRCAP,ADAM28,GGT5,GJB1,RUNDC3A,TNRC6A,ZNF638,GNAL,GNAS,LNX1,GPD2,NUDT21,TMEM121B,CECR2,GRB10,GRIA1,PLCD4,SERP2,GRM2,GRM7,BTN2A1,RNFT2,MAP4K5,MUM1,RASSF8,C1orf94,HLF,VSIG4,HPSE2,HMGCR,CPT1C,HSF2,HTR2A,LINC00667,C2orf72,KNDC1,KCNJ9,KCNK1,KCNK3,A1BG-AS1,STMN1,HECTD2,MAN2A2,ZFYVE27,MAP4,MAP6,MID1,PPM1L,MOBP,DBNL,COMMD5,PTOV1,MTR,LYRM9,LAYN,NAP1L1,NAP1L3,CCDC13,NF1,NKX2-2,NPTX2,NUCB2,OGG1,TREM2,PCDHGC3,PCSK2,CDK18,PDE1A,ENPP2,PFKFB2,PFKFB4,GDAP1L1,PKD1,JAKMIP1,PLXNB3,TRHDE,FA2H,PPP2R5C,PPP3CB,EPDR1,WBP1L,DEF8,WDR25,PTX3,ZNF615,TUG1,TMEM231,RAB3IL1,CEP97,RAD51D,ZNF793,ATG16L1,NWD1,DBX2,ZDHHC14,SLC6A15,GTDC1,RFX5,RGR,UBR7,RGS12,ARHGEF10L,TTLL7,SLC25A36,RNASEL,ROBO2,RORB,TMEM206,MRAP2,EPHA10,RPL15,BAALC,ADAL,RPS6KA2,ABCA11P,CLIP1,STX1B,AP1AR,DGLUCY,MAPK12,SATB1,HOGA1,SCN2A,ASIC4,MRAS,RASA3,SCG5,HKDC1,FNDC3A,ST3GAL3,CLSTN1,WDR37,ABLIM3,ZNF365,SLC1A3,RPH3A,SLC1A7,PEX26,DHX30,SMTN,PKNOX2,SLC6A9,RADIL,ARHGEF40,CCDC88A,SHANK2,BTBD7,ATF7IP,LGI3,CDK5RAP2,MBD5,CMTR2,SNRPN,DOP1A,SON,WDTC1,KIF21B,BDP1,KDM4C,IDI2-AS1,UNC5B,NFASC,TAB2,ATP10B,ITPRID2,LARP4,NXT2,ST5,ZSCAN29,SEPT8,CEP68,KANK1,FGD4,ABCC8,ZFR2,ARHGEF9,ARC,COBL,ANKRD28,TACC1,MCF2L,PDLIM2,TMEM136,KLHL4,ANO4,TBX15,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PHF24,PCDHB10,PCDHB3,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,AP4E1,TGFBR3,FBXL16,MTMR14,DDHD1,FAM124A,RIMBP2,KCTD2,CSMD1,TPD52,TPM2,CHST5,PRMT8,SMUG1,ELP5,STXBP4,TRPS1,ZMYND8,PPIL6,CLHC1,UGT8,PLEKHH2,MGAT5B,CCDC136,MEAF6,CCDC14,VLDLR,RBFOX3,XPO1,ZNF540,AMZ1,SLC30A4,EMSY,RGMA,CSDE1,GDPD5,LINC02210,STMN4,ADAMTS9,GAL3ST3,SNX27,DNAH10,TMEM63C,FAM219B,RNF170,IFT88,PRRT4,FAM198A,SPATA13" MicroRNA hsa-let-7d:mirSVR_lowEffct hsa-let-7d:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-144 1.18E-140 3.99E-143 3.67E-142 397 1774 "GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,PTCHD1,OLMALINC,INTS2,MTUS1,SNX32,KLHL13,PCDH19,KCTD16,OSBPL1A,ARHGAP20,FAM135A,MRTFA,BEGAIN,ANK1,ANK3,LCORL,PHF12,PPFIA2,PPFIA1,GPAM,CACHD1,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,CDK13,CHRD,NCOA1,CHID1,ATP2A2,ATP2B3,SLC2A11,B3GALT2,ADAM15,SNAI3-AS1,MPDZ,NIPA1,CACNB4,CALM1,PTBP2,CAST,MAP7,NFS1,ZNF501,USP6,CD86,LRBA,CDC25B,LRRFIP1,L3MBTL4,LARGE1,TIGD7,CLGN,NUMBL,ASIC3,MS4A7,EPS15L1,RAB33A,TPP1,ABCG2,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,IFFO1,SMARCAL1,RTTN,PNKD,SEC31B,CREM,CRY2,SLC32A1,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,PLXNA4,PPP1R16B,GREB1,SEC14L5,GAPVD1,TCAF1,DCAF8,ZFYVE16,ZNF337,KIAA0586,SPATA2,ZBTB24,MYEF2,BLOC1S6,DDX46,POM121,SNAP91,RABGAP1L,TMCC2,GRIN3A,CPEB2,DMTF1,DPH1,DSCAM,ARRDC4,ECM2,DNAJB6,DYRK1A,SNX29,EDNRB,ANKRD46,YAF2,EBI3,EGR3,RASA4,AASS,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,EPB41L2,COQ7,EPHB1,RABEPK,CDHR1,DUSP27,SIRPB1,KATNAL1,GMPR2,EZH1,ARMCX1,ABCA8,TUBB4A,CORO2B,DLC1,CHST15,TOMM40L,GTF2IRD2,CAP2,FOXF2,IP6K2,HVCN1,UFM1,FAM49B,TRIM16,TPK1,ATP6V1H,ZNF605,ERGIC3,MSANTD4,SARAF,HRASLS5,ZNF234,SIGLEC8,DISC1,ATP8A2,GHR,PPARGC1A,LYVE1,TOX3,GLUL,KDM2B,POLL,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA2,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,FICD,AP4S1,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,HMGCR,OPALIN,LRRC75A,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,KCNJ10,STXBP5,LAMP2,SYTL4,HECTD2,MAN2A2,MARK1,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,PABPC1L2A,NDUFA5,NEFM,NELL1,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,NUMA1,OXTR,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,PCSK1,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PLCB2,PLP1,HMGCLL1,C11orf49,TRHDE,SCHIP1,RANBP3L,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,TMEM260,PTPRD,PTPRG,FAM120C,SH3TC2,ATG16L1,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,TRIM68,KCTD17,DCUN1D2,KLHDC8A,CCDC102B,EPHA10,KIAA0895L,ACER3,PTGR2,MEG3,TRAPPC13,ATXN2,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,FOXRED1,HSPA4L,SH3BP2,ITSN1,CPEB3,WDR37,RPH3A,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,SLC8A2,ATF7IP,SLCO1A2,CPEB4,MAST1,MYH15,IFT122,FAM126B,USP33,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,GLT8D1,KDM4C,SPTB,TSPYL2,MCF2L2,RBM26,NPAS3,DDN,NFASC,TAB2,POGZ,ITPRID2,STOX1,SSTR2,SYT11,MLC1,FGD4,FNDC9,SLC37A2,TAC1,PDLIM2,VWA3A,TRIM2,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,HIF3A,RNF216P1,DICER1-AS1,AP4E1,FBXL16,ARL10,TIAM1,DAAM2,KCTD2,TNFRSF1B,C5orf64,NPL,TPM3,WBP2,CHST5,SMUG1,TRIO,STXBP4,TRPC3,TSC1,TTTY15,PRR18,CLHC1,SLC35A4,AMOT,ZNF709,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF28,ZBTB16,MEIS3,WNK1,CSDE1,EVI5,FIP1L1,TRIM16L,KAT6A,CASC15,NUP214,TIGD6,RNF170,SOCS4,ST8SIA2,LAS1L" MicroRNA hsa-miR-130a:mirSVR_highEffct hsa-miR-130a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.97E-144 1.67E-140 5.60E-143 5.16E-142 350 1385 "CLK4,NCKAP5,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,GPR158,HECW2,KCTD16,OSBPL1A,WDR35,HFM1,SPARCL1,SPOP,SRPX,FAM135A,MRTFA,LRCH2,LCORL,USP28,PHF12,APAF1,API5,SHROOM2,AQP4,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,STX16,ATP2B1,ZNF583,NOL4,DPY19L3,ADAM23,TTLL9,ADGRB3,NRP2,DST,SYNJ2,C5,THSD7A,KALRN,SYT6,CAST,MAP7,USP6,TIGD7,CFL2,KMT2C,ZFYVE9,PLAA,CLTC,NIPBL,CNR1,AKAP7,FAM149A,AKAP6,BTF3L4,ABI3BP,AHCTF1,ACBD5,MYRIP,HS3ST5,CLOCK,CREM,GDA,CSF1,LRIG1,CHD5,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,HDAC9,ARHGAP24,DCAF8,LONRF1,SPATA2,YTHDC1,ELMSAN1,ZEB2,FBXL5,KIAA0319,CEP170,RHOBTB1,SPOCK3,WDR20,RAB39B,CPEB2,DPYSL2,ABCC5,ABCC9,GOLT1B,AASDH,WDPCP,EDN1,ANKRD46,FSD1L,KMT5B,EGR3,CERCAM,PAN3,ENPP6,EPS8,RASL12,F3,ACSL4,TESK2,MED12L,FGF11,FGF14,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,NBEA,TACC2,TPK1,NPTN,MEGF10,GABRA1,HBS1L,GALC,B4GALNT1,NCKAP1,GAP43,ERAP1,MYOZ2,GCNT2,ARFIP1,SESN1,ADAM28,MALT1,RAB30,GLS,TNRC6A,KDM2B,MAP7D2,INSM2,RAB40B,FERMT2,PRUNE2,RAPGEF4,GRB10,GRM7,CIT,LINC00839,RNF165,BACH2,HNF4G,TLX1,NEGR1,IRF8,ZIC5,LRRCC1,LIX1,IL11RA,ZNF678,KCNN3,CREG2,LIG4,VWA5A,ARHGAP12,MAG,NAT8L,MAP4,MATN3,MBNL1,MDM4,MOG,ERICH3,CCDC80,BCO1,MTR,LYRM9,MYO9A,ZNF862,MYT1,NAP1L1,NAP1L3,NDUFA5,NEK1,NEUROD1,NFE2L2,CNOT4,NTRK2,OCRL,GPR88,OMG,OPHN1,LOC100128398,PCSK5,PDE1C,PDE3B,PDGFRA,DUSP26,CCSER2,ZFYVE21,ST8SIA5,JAKMIP1,PURG,LRP12,SCHIP1,POU3F2,PPM1B,CRLS1,PKN2,PSD,PLPPR1,MTMR10,PTHLH,EML5,PTPRG,RAB5B,PID1,CEP97,ATG16L1,RBBP8,KHDRBS2,ZDHHC14,RDX,RET,ERI2,SLC25A36,RPRD1A,KLHDC8A,CARF,ROBO2,EPHA10,ATP8B4,LRRK2,CNTNAP3,CLIP1,RTN1,SCN3A,FAM19A1,PEAR1,SEC14L1,ARX,KIF16B,DOCK10,MAGI3,CHD9,SLITRK3,SYBU,SEC31A,BTBD3,WDR47,RUFY2,SEPHS1,SLC8A1,CCDC88A,SHANK2,BTBD7,NAXD,SNAP25,SNCA,KIF13A,USP33,MYT1L,TRERF1,SOX5,DOK5,MYCBP2,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,STOX1,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,NUDT10,PLCB1,SYN2,ANKRD12,MTCL1,CAMTA1,CAMSAP2,FBXW11,PCDHB4,TEK,DICER1,ZFPM2,ITGB3BP,SLC44A1,BHLHB9,ERCC6L2,TMOD1,TNFRSF1B,R3HDM1,CSMD1,TNS1,TRPC3,TSC1,UBC,FAM155A,AMOT,SLAIN1,CCDC136,WRN,CLDND1,ZIC1,ZIC3,ZNF711,ZNF74,SPHK2,TCEAL7,ZBTB38,REEP1,FSTL5,WNK1,PMEPA1,MAP3K12,MFF,LRP8,CSDE1,STOX2,PCDH15,CAB39L,PLSCR4,RGS7BP,RTN4,UBE3B,PHTF2,NHSL1,SLC39A12,FXR1,FRMD6,SENP7" MicroRNA hsa-miR-101:mirSVR_highEffct hsa-miR-101:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.48E-144 4.20E-140 1.41E-142 1.29E-141 347 1365 "ACLY,SYS1,TKTL1,ARID1A,CCDC85A,ERMN,DPY19L2P4,ZNF608,OSBPL1A,LRRC7,SPOP,CEP126,UNC79,FAM135A,BEGAIN,DPP10,LRCH2,PPFIA4,PPFIA2,PPFIA1,APAF1,UPRT,ALS2,APP,SHTN1,LGR5,TMEFF1,SPTBN4,ARHGAP5,ASCL1,DACT3,B3GALT2,BARD1,BBS2,DCAF5,CDK5R1,SYNJ2,MTMR2,JAZF1,CACNB2,SPAG9,PRC1,CERS5,CCNH,MTMR7,CD86,CBFA2T2,TMEM257,C1orf52,CDC27,CDC42,CDH8,MAGI1,SRSF11,CHN2,NDST3,NRXN3,CLCN3,NRXN1,CLTB,TJP2,SULT4A1,CNTN1,ARMC8,MYRIP,ARHGEF10,CSNK1G3,SOCS5,PHACTR3,PHF14,PNPLA8,CTH,CTNND2,ZSCAN23,HDAC9,ARHGAP32,LONRF1,KIAA0586,PABPC5,ARMCX2,SPATA2,HEPH,CNIH3,TIAM2,KIAA0753,MAGI2,BLOC1S6,ZC3H11A,PLPPR4,NTM,RABGAP1L,CHRDL1,EXOG,RAB39B,NR1D2,CPEB2,DYRK1A,ABCC5,DNM1L,EDN3,PHF20L1,PLEKHA1,TMEM35A,EML1,CALCRL,EIF1,MTSS1L,ZNF549,TLR7,EYA1,SH3YL1,ACSL4,SCML2,RACK1,ST3GAL6,FER,KIAA1109,FGFR1,UBE2E3,MEX3B,SYNCRIP,FOXO3,ATP13A4,UFM1,STAMBP,ATP2C1,KHDRBS3,STAU2,STAG2,HBS1L,GALC,RAPGEF6,IQGAP2,ZNF559,DISC1,WASF3,ARFIP1,AHDC1,PCDH17,GK,RAB30,GPR75,GLS,TNRC6A,ZNF638,GPM6A,CECR2,RAPGEF4,ATP2B1-AS1,DIDO1,GRIK2,GRM7,KAT7,GUCY1B1,HAS2,MIER3,HMGCR,NEGR1,SHISA6,SMAP1,SOWAHA,ZNF385B,JAK2,KCNA1,KCNJ16,IPO5,STMN1,LIMS1,PACRG,MAP2,MAP4,MARK1,MBNL1,MDM4,MEST,KCTD6,MITF,XRRA1,MRPL42,MYCN,NACA,NAP1L1,NAP1L3,NEUROD1,NF1,OTOGL,NOVA1,NRCAM,CHAMP1,LOC100128398,CLDN11,GLIPR1L2,PAK3,PCDH8,ENPP2,GPR85,GNG2,CDK14,ZNF655,PURG,MAPKAP1,ING3,FA2H,FAT3,NXPH1,PPP3CB,PRKCB,GRAMD1C,HYDIN,DCHS2,DEF8,PTHLH,SPDL1,PTPRG,PTX3,USP47,ZNF493,RADX,KHDRBS2,REV3L,RFX4,UBR7,NUDT11,ZFHX4,LGI2,ZNF532,SETD5,CARF,ROBO2,RORB,MRAP2,FBXW7,ATP8B4,ADAL,TCP11L1,KCNIP3,RYR3,RMI1,AMER2,SEMA6D,ATXN7,SCN2A,SUPT20H,SGK1,CPEB3,FAM81A,PPP4R3A,BTBD3,CCDC88A,SLC12A2,TMEM132D,ATF7IP,SMARCA4,SORCS3,MYO16,SON,BDP1,FNBP1,SP2,HECW1,TEX2,SRPK2,POGZ,NKAIN2,LRRC4,ERBIN,MAPK8IP3,NEK4,AJAP1,GSE1,PRRC2C,VPS13A,SYT1,SYT4,MTCL1,CAMTA1,TAL1,CAMSAP2,FBXW11,TCEA1,TCF4,DMXL2,TCF7L2,ZEB1,TCF12,CLASP1,WDR7,NSD1,PCDHAC2,PUM2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,SIRT1,ZFPM2,ZMAT3,TGFBR3,HHIP,HEY1,TK2,ACTR6,BHLHB9,ERCC6L2,RIMBP2,KAT6B,RASD2,RUNDC3B,SSBP2,TTC3,TMEFF2,HIRA,CADM1,PITPNB,FLRT2,PLEKHH2,VLDLR,ZNF781,SF1,PCDH20,ZFP37,ZBTB14,ZIC1,ZNF711,ZNF17,TRIM9,MKRN3,TFIP11,SLC30A4,EMSY,CADM2,EVI5,KCNAB1,MPPE1,SLC17A6,ST7,KAT6A,PHTF2,CERS6,ADAMTSL3,JMJD1C,KLHDC1" MicroRNA hsa-miR-22:mirSVR_lowEffct hsa-miR-22:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-143 5.68E-140 1.89E-142 1.74E-141 382 1653 "ACLY,CLK4,EMILIN3,NBAT1,CSMD2,ADCY2,ADCY6,ADD1,BRAP,SORCS1,ADORA1,ADRA1D,ADRA1B,SLC24A4,AP2A2,INTS2,PCDH19,AK2,SPARCL1,ALCAM,SYT13,DOC2A,BIN1,DPP10,ANK2,PKP4,BCAS1,TNRC6C,SHTN1,LGR5,SHROOM2,CDK10,ARNTL,ASCL1,CHRD,NCOA1,NUMB,SLC2A11,N4BP2L1,ADGRB3,ZNF599,CFLAR,KSR1,ST3GAL5,CASTOR3,MTMR2,GYG2,NIPA1,CALB2,CABP7,DIRAS1,KALRN,TRIM41,CBR1,P2RX6,ARHGEF1,DGKI,REPS2,LRRFIP1,LARGE1,IGFN1,SRSF11,CHM,JAM2,EPS15L1,RAB28,ZFYVE9,COG1,SLC24A2,STOML1,CLTA,DNAJB5,HECTD1,RAB26,HOMER3,AKAP6,SLC4A8,TCEAL2,RTTN,ENTPD4,CRHBP,GDA,SNCAIP,CSNK1E,GALNT9,RIMS4,KIAA0040,PHF14,CTH,GREB1,NRSN1,ZFYVE16,KIF26A,PHYHIP,IST1,TOMM20,ZEB2,B3GAT3,COPS7A,SMG7,SPOCK3,SV2A,SRGAP3,RABGAP1L,TMCC2,EXOG,DNM1,SLC29A4,DNM2,DPH1,DRP2,DTNA,GOLT1B,AASDH,FAM135B,PHC2,SEMA3D,GPR61,TMEM132E,ASB3,TNK2,MRNIP,BSCL2,ELN,TMEM35A,EMX2,TUBD1,EPB41,MFSD10,ANKRD13B,MRVI1,CLVS1,CACNG3,ATP8A1,CHST15,TESK2,FER,FGFR1,CAMSAP1,SUCO,SCARA3,AGAP3,FLT1,PSD2,NOP56,FOLH1,WDR83,SORBS1,ARFGAP2,ATP2C1,CGREF1,STAU2,DOT1L,MEGF11,GALNT15,CAB39,MTHFD2,DISC1,SEPT9,LRRC37A6P,TUBA8,GGT7,CRCP,COPS8,MSL3,POLL,DCLK2,GPT2,GPD1,GPD2,CCDC184,EML4,CECR2,DIDO1,ADAMTS13,NR3C1,CIT,KAT7,ZBTB49,PSIP1,SLC2A6,ATOH8,WIF1,PADI2,PTGDR2,HMGB1,HNRNPK,NEGR1,OPALIN,IGF1,TJAP1,IL6ST,IL11RA,DIPK1A,ITPKA,KCNC1,KCNK1,KCNMA1,KIF5C,LIG4,VWA5A,LSS,MBNL1,SYT9,MEIS1,KCTD6,AFDN,MOBP,MOV10,SAMD5,COMMD5,MT3,ZNF862,NAP1L1,NEUROD1,NFYA,VWA2,CNOT4,SMIM11A,NTRK2,OGDH,OPHN1,PAX6,PBX1,PCDH9,PDE2A,ENPP2,GNG2,PENK,CDK14,XRN1,LRP12,PRRX1,EPB41L4B,FA2H,CRLS1,PRKCB,MAPK10,HYDIN,APTX,SIDT1,SNRK,CNTLN,MTMR10,ELOVL2,PTN,PTPRE,PTPRN,PEX2,CCDC40,TRIM68,DPF2,RET,RGS10,RGS12,ARHGEF10L,RNH1,LGI2,MYH14,TMLHE,KLHDC8A,ALG9,ARMC5,CCDC25,SNX22,RPL15,ZC3H14,CNTNAP3,FAM161B,HUNK,NCBP3,TRAPPC13,FAM192A,MAPK12,SEMA6D,ATXN2,ATXN7,HOGA1,SCN4B,PRCD,SCP2,SEC14L1,TRIM46,ZNF821,KIF21A,FAM102A,DOCK10,MAGI3,FHOD3,PAAF1,SLC1A3,FAM81A,BTBD3,DHX30,SLC6A1,KANSL3,LRRC55,SLC6A8,ARHGEF40,SLC9A5,BTBD7,SLC20A2,EPC1,MYH15,LIMCH1,USP33,WDTC1,SOX3,BDP1,ZSWIM8,MYCBP2,KDM4C,PEG10,ZNF423,CAMTA2,MESP1,ELOVL4,SYN2,C12orf76,ANKRD12,SEMA4A,MLST8,MCF2L,UNC5D,ANO4,TCF7L2,TRIM2,RPGRIP1L,AZIN2,DOCK9,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,DNAH7,ZFPM2,GALNT17,TIAM1,RELL2,TK2,ZFP91,HEY2,DAAM2,TNFRSF1B,TPM3,ZNF346,PRMT8,PPIL6,KCNE5,CLHC1,SLC35A4,AMOT,VLDLR,CLIP2,NPDC1,ZNF19,ZNF24,PCBP1-AS1,SMARCAD1,INTS3,WNK1,SLC30A4,CADM2,PRTFDC1,STMN4,STOX2,SEMA3B,FAM47E,MVB12B,EPM2A,RGS7BP,DOCK8,MARCH8,UBE3B,KAT6A,FRMD6,SENP7" MicroRNA hsa-miR-183*:mirSVR_highEffct hsa-miR-183*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-143 5.73E-140 1.90E-142 1.75E-141 384 1670 "ASIC2,ARID1A,ADCY2,ADD1,ADD3,RNF150,SLC44A5,INTS2,OSBPL8,C1QTNF3,LRRC7,SPARCL1,ALCAM,PCDH10,FAM135A,AMPH,ZFAT,ANK2,MAP4K3,PHF12,ALS2,BCAS1,SHTN1,AQP4,MIER1,ARHGAP5,CDK13,ASPH,DDX3Y,ATP2B1,B3GALT2,NOL4,BACH1,DST,SYNJ1,OSGIN2,CACNB4,CALB1,VSTM2A,SPAG9,KRIT1,CCNH,USP6,SCARB1,DGKI,LRBA,SEPT7,CDC27,CDC42,LGI1,LARGE1,CHM,CHN2,CASC2,B4GALT6,CLCN3,NRXN1,CLU,ABCG2,QKI,CNR1,ARMC8,AKAP6,SLC25A27,AKAP5,SLC4A7,ABI3BP,COX4I1,AHCTF1,CLOCK,PREPL,ANKRD44,NCOR2,SNCAIP,LRRC3B,ARHGEF10,ATRNL1,VCAN,NCAN,PNPLA8,CTH,ZSCAN23,KATNAL2,RIPOR2,LIN54,MATR3,KCTD8,DAPK1,PABPC5,DNAJC6,ZNF804A,C8orf34,ZEB2,HP1BP3,KIAA0319,CEP170,MAGI2,DDX46,SNAP91,SACS,SPOCK3,RABGAP1L,WDR20,DMD,USP3,CDON,DMTF1,DPP6,DPYSL2,PDCD6IP,DYRK1A,GOLT1B,EDIL3,EDNRB,SEMA3D,FRY,FSD1L,OPTN,MBNL2,KMT5B,AASS,KCTD3,ELAVL2,ELAVL4,PAN3,EIF1,KCNMB2,SRRM1,CLVS1,ZIC4,EFEMP1,FKTN,ZSCAN30,GORAB,GTF2IRD2,KIAA1109,POLR1B,FGFR1,POLK,UBE2E3,HPCAL4,JKAMP,TACC2,DACH2,TVP23A,PHYHIPL,GAB1,GABRA1,GABRA5,CAB39,GAP43,ERAP1,GATM,SESN1,GHR,MALT1,GK,RAB30,GLRB,TNRC6A,PCDH11X,ZNF638,LUZP2,ADGRA3,GPD2,PRUNE2,LILRA1,GPR37,GRIA1,GRIA4,PLCD4,GRIK3,TMEM25,LINGO1,GUCY1B1,HPS5,FRMD3,BACH2,MIER3,HMGB1,SCRG1,HNF4G,C9orf129,MSL1,LRRCC1,IGSF1,IL6ST,ZNF678,LRRTM3,SLC35G1,METTL21A,OLFM3,KCNK2,KIF5A,STXBP5,LAMA2,INSYN2,LIMS1,ASPRV1,MARK3,MAT2A,MATN3,MBNL1,SYT9,MEIS1,MEIS2,SRSF12,MOBP,MSR1,CTNNA3,RTL5,MYT1,NEUROD1,NF1,NFE2L2,NOVA1,DNHD1,IGSF11,OPHN1,CNTN3,PCSK1,CDK18,PDE4B,PFKFB4,ZNF655,FAM218A,FAM216A,HMGCLL1,PURG,ANKRD16,RC3H2,ING3,SPATA6,PPP2R5C,PPP3CB,PPP3CC,PKN2,GRAMD1C,VPS13C,SNRK,MDGA2,PTPRO,RAB5B,PID1,RAD17,ZNF493,OXR1,RASGRF2,ARID4A,FEZF2,RDX,RFX5,SLC25A36,ZFHX4,LGI2,CCDC82,EXD2,CARF,GSTCD,CCDC102B,NEK11,SPIN3,ATP8B4,ACER3,LGR4,ABCA11P,KCNIP3,ZNF354C,SALL1,SATB1,LRFN5,SCN2A,SCN3A,FAM19A1,ELMOD1,SEC14L1,HSPA4L,FERMT1,KIF16B,CHD9,FNDC3A,FHOD3,R3HDM2,NLGN1,CTXN2,ANKRD6,FAM81A,RUFY2,KANSL3,ZNF430,SEPHS1,CCDC88A,SLC9A5,SLC12A2,SLCO1A2,SLC22A4,CPEB4,SLN,OGDHL,SMARCE1,RCOR3,ANKRD36,RIMS1,ZNF415,SNRPN,SOX5,ENKUR,GLT8D1,KDM4C,RBM26,PBLD,CLASP2,POGZ,ITPRID2,STOX1,NKAIN2,NXT2,SEPT8,CEP68,ADHFE1,ACSBG1,KLHL7,DNAJC9,PLCB1,SYPL1,COBL,MTCL1,PJA1,CAMTA1,ADGRL3,TBCEL,TMEM136,TBX15,TCEA1,SATB2,ZFP90,RPGRIP1L,WASHC4,PCDHB7,PUM2,USP32P1,ZFPM2,AP4E1,AKTIP,SLC44A1,TJP1,DDHD1,HEY2,TMPO,NEIL2,PPIL6,ANO5,TUBB1,UBE3A,DNAJC12,ZNF781,NSD2,CLDND1,RICTOR,ZNF711,ZNF708,ZNF28,KCNT2,GPR158-AS1,ZNF138,ZBTB16,FSTL5,ZNF189,FTSJ1,MAP3K12,CADM2,ADAMTS9,HPS4,PCDH15,PPP1R3F,TMEM163,WNK3,PLSCR4,PDSS2,CASC15,ADAMTSL3,SOCS4,SLC4A10,ZNF30" MicroRNA hsa-miR-499-5p:mirSVR_lowEffct hsa-miR-499-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-143 6.90E-140 2.28E-142 2.10E-141 380 1637 "SDE2,ABAT,ABR,KDM5D,ADAR,KLHL32,TMEM132B,ADCY2,SLITRK1,ADD3,AXIN2,CDC7,USP31,NLGN4X,ZNF608,SORCS2,ARHGAP20,CARNS1,ZFAT,FGD2,PHF12,PPFIA1,APC,EPB41L5,ALS2,USP37,LGR5,AQP4,TMEFF1,ASCL1,ASPH,ZBTB10,ATP2A2,ATP2B1,BACH1,DCAF5,KSR1,BMPR1B,SYNJ2,ARHGEF7,JAZF1,PRMT9,C5,OSGIN2,CFAP410,DDR1,CACNB4,KALRN,MAP7,RGN,MTMR7,INA,LRBA,CDH2,DCLK1,LOC730101,NDST3,IGFBP7-AS1,KIAA1549L,NRXN1,CLU,CLTC,FBXO7,ABCG2,MAP4K4,NIPBL,IQCK,AKAP5,ABI3BP,RCHY1,TBPL1,RTTN,ZNF521,NRG2,HS3ST5,RBM39,GDA,RGS6,SOCS5,VAC14-AS1,CNTNAP2,PLXNA4,FAM169A,DZIP3,PLCXD3,RIMS2,BOC,DOCK4,ARHGAP32,ZFYVE16,ZNF337,TM9SF4,MAML1,SCRN1,YTHDC1,HP1BP3,FBXL5,KIAA0319,MED24,ZC3H11A,DLG2,GRIN3A,DMD,DPP6,ABI1,DTNA,TOM1,WDPCP,KLHL5,TMTC1,MRO,LPAR6,EIF4G1,IRAK4,ELAVL2,RGS17,CALCRL,RCAN2,IGSF6,RTN3,F3,NSRP1,TAOK3,FKTN,SLC9B2,FGF13,SUCO,UBE2E3,MEX3B,PCYOX1,SYNCRIP,FLT1,NELFCD,FAM49B,PNMA2,KBTBD12,SARAF,TBR1,ZNF512,MEGF11,MEGF10,HBS1L,B4GALNT1,ERAP1,WASF3,MYOZ2,IGSF5,MSTN,WASHC2A,GFRA1,PCDH17,TCERG1,GLI2,GLYR1,ZNF638,GNAL,GNAO1,PSRC1,GPD2,PRUNE2,GPR12,GPR22,NUDT21,PCLO,GRIA2,RFFL,BVES,PSIP1,FAM107A,ADAMTS6,MAP4K5,IGSF21,BACH2,GABARAPL2,HNF4G,IGFBPL1,CELF5,IGF1,IL6R,IL6ST,BRINP3,LRRTM1,SLC35G1,METTL21A,KCNA1,KCNC2,KCND2,KIFC3,IPO5,STXBP5,KTN1,LAMP2,LMO2,ARHGAP12,MARK3,MATN2,MBP,LRP1B,KITLG,WDR49,MPP2,ZNF680,BLOC1S2,NRBP2,N6AMT1,CTNNA3,MYO6,MYO9A,NEXMIF,NCAM1,NCAM2,NELL2,NEUROD1,SLC11A2,NRCAM,CHAMP1,PAX6,PCDH9,PDCD2,PDE1A,PDE3B,NLGN3,SEMA5B,PIK3CD,CCSER2,XRN1,FTO,MAPKAP1,STRN3,LRP12,PSAT1,ING3,EPB41L4B,NXPH1,MINDY2,PPP3CB,MAPK8,MAPK10,HYDIN,PIGG,CNTLN,ANKHD1,UHRF1BP1,PTHLH,OCIAD1,PTPRG,PTPRO,PPP2R3C,CEP97,FAT4,FAM184A,ENOX1,ARID4A,RADX,BSDC1,RFX3,RGS3,RGS12,SEC61A2,RIC8B,PBRM1,ALG9,RAVER2,ROBO1,RPL15,ATP8B4,LRRK2,LGR4,MEG3,FAM182A,RMI1,SALL1,SATB1,FNIP1,SOX6,GALNT10,SUPT20H,HSPA4L,ZFP30,KIF21A,PPM1E,FBXO11,SEC31A,WDR37,SLC1A3,FAM81A,EPN2,CCDC88A,ELMO2,SPHKAP,LMBRD1,UNC80,USP33,SCN3B,DOP1A,SOX11,KDM3A,SP4,ARHGAP26,ZBTB43,SPART,SRPK2,ATP10B,CAMTA2,POGZ,EPB41L3,ZC4H2,NEK4,TTBK2,RGL1,KANK1,AJAP1,FGD4,PRRC2C,NUDT10,DNAJC9,SYN2,MTCL1,CAMTA1,DNMBP,FAM208A,KIAA1107,WWC1,TMEM136,SATB2,TRIM2,TCF12,DOCK9,PHF24,PCDHB3,NSD1,GPRIN3,HIF3A,SIRT1,C18orf54,SLC44A1,ARL10,TK2,ACTR6,DDHD1,ERCC6L2,HEY2,TMOD1,KAT6B,TP53BP1,TRO,TRPC3,TRPS1,ZMYND8,PPIL6,UBE3A,UGT8,ZNF709,RICTOR,XRCC4,ZIC1,ZNF24,MICU3,ZNF28,CFAP52,FMN2,ZBTB16,POLR3H,ANKS1B,SPIRE1,INTS3,CA10,EMSY,SLC38A1,EVI5,SCG2,NAV2,WNK3,SLC17A6,GOPC,AMN1,PHTF2,ZNF248,VANGL2,FXR1" MicroRNA hsa-miR-885-5p:mirSVR_lowEffct hsa-miR-885-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-143 7.55E-140 2.49E-142 2.30E-141 367 1529 "ACADM,ABHD6,ACTN2,ARID1A,FMNL2,KLHL32,SLITRK1,ADD1,ADD2,ADD3,CDC7,SORCS1,PWWP2A,KIDINS220,SLC44A5,KCTD16,OSBPL6,HFM1,SPOP,ALCAM,UNC79,ALK,AMPD2,ZFAT,LRCH2,ANK2,LCORL,PHF12,PPFIA1,PKP4,APBB2,USP37,APP,PPP4R4,ZFYVE28,ASCL1,ASPH,NUMB,ATP1A1,SLC4A4,ATP2B1,MTMR9,ARHGEF7,GPC2,BTRC,KALRN,VXN,ISPD,RUNX1T1,PRC1,CBR1,MTMR7,INA,LRBA,LGI1,DLGAP2,DLGAP1,TIGD7,CCPG1,SRSF11,SOCS6,CHM,CASC2,CNOT8,EPS15L1,DNAJB5,SULT4A1,NIPBL,ARMC8,COL4A5,BTF3L4,AKAP5,AHCTF1,MYRIP,SLC35F1,RBM39,RNF14,PDE4DIP,PHF14,PUM1,RUBCN,DOCK4,ZFYVE16,CENPL,EARS2,MATR3,DAPK1,BRINP1,DNAJC6,B3GAT3,CEP170,DDX46,NTM,KBTBD11,RPS6KL1,CALN1,NR1D2,CASP8AP2,DPP6,RCAN1,DNAJB6,ABCC5,EDN1,SEMA3D,SH3GLB1,MRO,EGR3,AASS,TENM1,ELAVL3,C3orf18,EIF1,SEZ6,KCNMB2,GPHN,RACK1,TESK2,KAT8,GORAB,SEC24B,SLC9B2,FER,GTF2IRD2,POLR1B,FGF14,FGFR1,TMEM164,PRKAG2,FHL1,SUCO,SEC23B,CAP2,SYNCRIP,ANKFY1,C2orf88,ZNF605,DACH2,NSG1,DLL3,TVP23A,MEGF11,MEGF10,GABRA2,GALNT15,CAB39,GAD1,BRPF3,ZMYND11,GALC,GALR1,IQGAP2,GAP43,SIGLEC8,KIAA1841,GATM,SULT1C4,ARFIP1,GGT7,TCERG1,PCDH11X,HTATSF1,DCLK2,GNAO1,WDFY3-AS2,GPM6A,GPM6B,ATF7,STMN2,GRIK2,ADAMTS8,NR3C1,GRM7,BTN2A1,TMEM25,HPS5,ZHX1,ARHGAP36,MIER3,HMGB1,HMX1,HNMT,IDH3A,IDH3B,DOCK7,DIPK1A,ITGAV,SLC35G1,METTL21A,KCNA4,KCNA6,CREG2,KIF5C,CYP27C1,STMN1,ZFYVE27,MARK3,MAT2A,MBP,MEIS1,MIA2,MMP16,ADAM22,MXI1,MYT1,FXYD6,ZC3H12B,CCDC13,NELL2,SLCO1C1,OTOGL,NOVA1,HCN1,OPA1,OPCML,OPHN1,PCDH8,PDE4B,DUSP26,TMIE,SNX10,STRN3,RC3H2,MED1,PPM1B,KANSL1,RANBP3L,SAMD9,QRICH1,CNTLN,ANKHD1,BDNF-AS,MTMR10,EML5,C1orf109,USP47,ENOX1,ZNF493,RBBP6,RADX,VEPH1,MSANTD2,SLC6A15,REV3L,CCDC82,EXD2,ROBO1,TMEM206,YY1AP1,ELP2,CCDC102B,RPL15,ARMH4,KIAA0895L,MCMBP,ATP8B4,CNTNAP3,RTN1,SEMA6D,SOX6,SELL,SFPQ,ASRGL1,TRA2B,SCAF8,SGK1,ARX,FNDC3A,SLITRK3,NLGN1,ABLIM3,WDR47,SLC6A11,RAB3GAP1,ZNF334,SLC15A2,SPHKAP,GKAP1,COA1,RCOR3,TTC17,ANKRD36,CABCOCO1,TMCC1,PDZRN3,USP33,SOX5,NMNAT2,KDM4C,ZC3H13,KIF1B,TSPYL2,ATP10B,ITPRID2,ZC4H2,SS18,ZSCAN29,NEK4,CEP68,FAM168A,VPS13A,NUDT10,PJA1,DNMBP,ADGRL3,FBXW11,ANO4,ACSL6,VWC2,TCF4,TCF7L2,RPGRIP1L,DOCK9,PCDHB9,PUM2,TEK,ZFPM2,ITGB3BP,AP4E1,HHIP,AKTIP,NR2E1,TMOD1,BEX4,TPM1,NPL,SYNPO2,STXBP4,TRPC3,DCBLD1,TSN,TTTY15,LRTM2,PRR18,SLAIN1,PITPNB,ZNF709,VLDLR,BEST1,WIPF1,RICTOR,ZIC2,ZNF711,AGMO,GPR158-AS1,MKRN3,LYPD6,CELF4,ZBTB38,DPYSL5,PLPPR5,SMARCAD1,WNK1,CA10,PRDM2,RGMA,RNF103,SCG2,TMEM163,MPPE1,C12orf4,FAM13C,DOCK8,SMIM8,FBXO36,ACTR3B,MSRB3,AP3B2" MicroRNA hsa-miR-570:PITA hsa-miR-570:PITA_TOP PITA 2.17E-143 1.22E-139 4.00E-142 3.69E-141 300 1016 "ABAT,KCNH8,ARID1A,ELFN2,SLITRK1,ADCY6,SORCS1,ADRB2,NLGN4X,INTS2,PCDH19,HACE1,SEMA6A,GPRASP2,AMPH,DPP10,MAP4K3,GAS7,APP,AQP4,TMEFF1,BRINP2,ATP2B1,ATP2B2,NOL4,ADGRB3,DCAF5,NAE1,SCAPER,CACNB4,CALB1,CAMK2A,CAMK2G,CANX,SPAG9,REPS2,DCLK1,L3MBTL4,CCPG1,CFL2,COPB2,SRSF11,SOCS6,CHN1,CHN2,KMT2C,NRXN1,QKI,RAB26,CNN3,AKAP6,COL9A1,BAG4,MYRIP,ZNF521,IGDCC3,SLC35F1,CREM,AATK,CSNK1E,PLCXD3,NRSN1,ST18,FAM131B,TOX,RIMS3,IST1,DGKB,GIT2,SIRPA,DCC,PLEKHM1,MYEF2,KIAA0753,DDX46,SMG7,DLG3,RAB39B,DMD,USP3,CALN1,CPEB2,DNAJB6,FRY,OPTN,RBM12,YAF2,SH3GLB1,MBNL2,ABI2,EIF4G2,ELAVL2,TMEM35A,PAN3,EIF1,EPB41L2,KCNMB2,ETV1,RTN3,RRAGB,KATNAL1,CACNG3,CORO2B,ATP8A1,FGF13,PRKAG2,FOXF2,FOXO3,ANKFY1,AFF2,SMC2,MSANTD4,PHYHIPL,STAG2,CHL1,GABRB3,SALL3,C15orf41,FAXC,GCNT2,MSTN,AHDC1,SPIN1,TNRC6A,PCDH11X,GPD2,GPM6A,GPR19,RAPGEF4,GRB10,GRM1,GRM7,CIT,PTPRT,PSIP1,MAP4K5,HRH3,TNFAIP8L3,HLF,SYNPO,HNF4G,TLX1,HSF2,HSP90AA1,SMAP1,C5orf24,ZIC5,JAK2,KCNB1,KCNJ3,KCNK2,KTN1,MAP2,MAP4,MBNL1,CHIC1,LRP1B,MEF2C,MEIS2,MN1,MYBPC1,NEXMIF,MYT1,NCAM1,NEFH,NFIX,CNOT4,LRIT2,HCN1,OCRL,GPR88,OPA1,GPR137C,PRTG,CDK14,PIK3C2A,LRP12,PRRX1,FAT3,MED1,PPP3CA,PPP3CB,KANSL1,PROX1,RELN,WBP1L,SNRK,PTCH1,PTPRD,PTPRG,FAM120C,NKAIN1,RADX,KHDRBS2,RDX,REV3L,RFX3,PBRM1,LGI2,ZNF532,ROBO1,RORB,RPE,TMEM100,LGR4,SEMA6D,SATB1,ATXN1,ATXN7,ELMOD1,CASC3,TRA2B,COPZ1,NLGN4Y,PPP1R9A,PPM1E,CPEB3,NTNG1,CHD9,FNDC3A,SLITRK3,SLC1A2,PKNOX2,SEPHS1,SLC8A1,TRIM67,ELMO2,TET1,LMBRD1,PALLD,KDM4B,SOX1,MYT1L,ZCCHC24,ZHX3,SP4,HECW1,TEX2,ARHGAP26,CDK19,RBM26,CLASP2,COLGALT2,EPB41L3,LARP4,NSFL1C,NECAB1,SYT11,PRRC2C,VAMP1,C3orf70,ANKRD12,CAMTA1,CAMSAP2,VWC2,TCF4,TRIM2,TCF12,SYNE1,RALYL,PCDHB7,ARHGEF12,SIRT1,HHIP,SLC44A1,ARL10,ZFP91,ERCC6L2,LRRC8A,RIMBP2,R3HDM1,KAT6B,SEZ6L,TRPS1,CADM1,UBTF,MEAF6,XPO1,ZBTB14,ZIC1,ZIC3,FMN2,PLPP4,TMEM237,ZFAND5,SMARCAD1,WNK1,CA10,PMEPA1,CADM2,PRDM10,SLC17A6,RGS7BP,FAM13C,RTN4,KLHDC1,FXR1,FRMD6,SOCS4,GAN" MicroRNA hsa-miR-98:mirSVR_lowEffct hsa-miR-98:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.61E-143 3.15E-139 1.03E-141 9.52E-141 384 1678 "CSMD3,GALNT16,GALNT13,SLC12A5,SORCS1,PLEKHH1,UNC5A,OLMALINC,INTS2,MTUS1,KLHL13,PCDH19,KCTD16,OSBPL1A,TXNDC16,AK2,C1QTNF1,ARHGAP20,FAM135A,MRTFA,BEGAIN,CDC42BPA,ANK1,LCORL,PPFIA2,PPFIA1,GPAM,AMER3,SHTN1,AQP6,CDC14B,MIER1,SEMA4G,IGDCC4,CDK13,CHRD,NCOA1,ATP1B3,ATP2A2,ATP2B3,SLC2A11,B3GALT2,NOL4,ADAM23,ADAM15,MPDZ,NIPA1,CACNB4,PTBP2,SYT6,CAST,MAP7,USP6,CD86,LRBA,LRRFIP1,L3MBTL4,CLGN,NUMBL,ASIC3,MS4A7,EPS15L1,TPP1,ABCG2,ARMC8,AKAP6,BTF3L4,LETMD1,ABI3BP,SMARCAL1,RTTN,PNKD,SEC31B,CRY2,SLC32A1,GDA,TRIM69,CS,RGS6,LRIG1,CSNK1E,PLXNA4,PPP1R16B,CMTM5,GREB1,DCAF4,SEC14L5,GAPVD1,DCAF8,ZFYVE16,ZNF337,TBC1D5,KIAA0586,DCT,ZBTB24,BLOC1S6,DDX46,POM121,SNAP91,TMCC2,GRIN3A,DOCK2,DMTF1,DPH1,DSCAM,ARRDC4,ECM2,DYRK1A,ABCC9,SNX29,EDNRB,ANKRD46,RBM12,YAF2,EBI3,EGR3,RASA4,GOLGA7,SORBS3,CERCAM,ELAVL4,STARD3NL,VPS13B,EPB41L2,DMTN,EPHB1,RABEPK,NCALD,CDHR1,KATNAL1,GMPR2,EZH1,ARMCX1,TUBB4A,CORO2B,DLC1,CHST15,TOMM40L,GTF2IRD2,CAP2,FOXF2,IP6K2,FLT1,EFCAB2,HVCN1,UFM1,FAM49B,USP21,TPK1,CAMKK2,ATP6V1H,ZNF605,ERGIC3,SARAF,HRASLS5,DISC1,ATP8A2,SULT1C4,GHR,PPARGC1A,LYVE1,TOX3,MSL3,GLUL,KDM2B,POLL,GOLGB1,ATF7,STON1,GPR26,TMEM121B,GRIA4,GRIK2,GRIK3,SPACA9,RNF165,TMEM25,BVES,FICD,AP4S1,RABL2A,LINGO1,MAEL,HAS2,LINC01102,HLF,HMGCL,OPALIN,SMAP1,FAM95B1,MYLK2,C2orf72,IL11RA,INPP5B,ZNF385B,SLC35G1,KCNC1,KCND1,LAMP2,SYTL4,HECTD2,MAN2A2,MAT2A,MBNL1,MDFI,LRP1B,AFDN,ADAM22,MSR1,MTTP,C10orf105,MYCN,PABPC1L2A,NDUFA5,NEFM,ALDH1L2,NME4,NPR2,SLC11A2,NTRK2,NTRK3,P2RY1,PAK3,CNTN3,PAX6,PBX1,PCDH9,CDK18,PRTG,PFKFB3,CDK14,GDAP1L1,TMIE,ZNF655,PLCB2,PLP1,HMGCLL1,PURG,TRHDE,MAPKAP1,SCHIP1,RANBP3L,PRKACB,RAB39A,PKN2,GRAMD1C,KLK6,BCAS3,SLC22A23,LRRC49,LAMA1,DEF8,WDR25,PIGG,PTAFR,TMEM260,PTPRD,CASTOR1,PTPRG,FAM120C,TUG1,SH3TC2,ZNF493,RASGRF1,RASGRF2,ZDHHC14,BSDC1,SLC6A15,KCTD17,RIT2,ZNF532,DCUN1D2,EXD2,KLHDC8A,ROBO2,CCDC102B,UEVLD,KIAA0895L,ACER3,PTGR2,MEG3,RTKN,TRAPPC13,ATXN2,SCN4B,PRCD,ASIC4,SEC14L1,CASC3,FOXRED1,HSPA4L,SH3BP2,ITSN1,CPEB3,ST6GAL1,WDR37,RPH3A,SLC1A7,BTBD3,EPN2,RUFY2,FAM214B,SLC6A1,SLC8A2,ATF7IP,CPEB4,MAST1,MYH15,IFT122,FAM219A,DOP1A,SPATA7,KDM3A,ZSWIM8,KDM4C,TSPYL2,RBM26,NPAS3,DDN,TAB2,POGZ,ITPRID2,STOX1,SYT11,MLC1,FNDC9,PLCB1,TAC1,PDLIM2,FBXW11,VWA3A,RPGRIP1L,SYNE1,FAM189A1,SLC19A3,PCDHB6,AKNA,USP32P1,AHCYL2,RNF216P1,AP4E1,FBXL16,ARL10,TIAM1,TK2,ERCC6L2,KCTD2,TNFRSF1B,NPL,CHST5,RGMB,SMUG1,TRIO,STXBP4,TRPC3,TSC1,ANO5,TTTY15,PRR18,CLHC1,AMOT,UGT8,ZNF709,VSNL1,WIPF1,ZNF781,ETNPPL,PCDH20,ZNF28,ZBTB16,ANKS1B,MEIS3,WNK1,LRP8,CSDE1,EVI5,TRIM16L,KAT6A,CASC15,NUP214,TIGD6,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-1264:mirSVR_highEffct hsa-miR-1264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.46E-143 5.32E-139 1.74E-141 1.60E-140 385 1689 "ABCF1,KCNH8,ACADM,CLK4,ARID1A,CSMD3,FMNL2,PLEKHG5,HHATL,CDC7,KIAA1211,PTCHD1,INTS2,OSBPL1A,AK2,ADGRF5,LRRC7,ALCAM,SRPX,ARHGAP20,FAM135A,OGT,CDC42BPA,LRCH2,CCDC146,LCORL,BCAS1,APP,MIER1,PPP4R4,TMEFF1,CDK13,STK33,CAPRIN2,ASPH,ATM,ATP1B3,ATP2B2,DPY19L3,ATP6V1G2,KIF1A,ADGRB3,CFLAR,SYNJ1,ST3GAL5,FUBP1,SCAPER,MTMR3,JAZF1,OSGIN2,CA8,CACNB4,THSD7A,KALRN,CAMK2G,CANX,CLDN10,INA,ZMYM4,L3MBTL4,MAGI1,SRSF11,CHM,CASC2,CNOT8,SLIT2,NRXN3,ZFYVE9,NRXN1,TPP1,TJP2,QKI,ARHGEF6,CNTN1,AKAP7,COL4A5,SLC4A7,SLC4A8,AHCTF1,CNRIP1,MFSD4A,SLC35F1,FAM171B,HAPLN1,HINFP,CLIP3,CS,ATRNL1,SIPA1L1,NCAN,SOCS5,PDE4DIP,PLXNA4,UBXN2A,PHF14,CYBB,ARHGAP32,RIPOR2,TOX,TMEM170A,PITPNC1,ARMCX2,ZEB2,FBXL5,CEP170,RABGAP1L,WDR20,CHRDL1,DLG2,DTNA,E2F5,WDPCP,EDN1,EDNRB,CELSR3,FAM13A,GPR61,EGR3,RASA4,STARD3NL,PAN3,DCTN4,USPL1,TUBD1,LRRC17,ETV1,F5,ARMCX1,FABP7,CEP78,TESK2,MED12L,KIAA1109,FGF13,POLK,SUCO,SYNCRIP,SEMA4D,C2orf88,JKAMP,TMEM107,ZBED3,UFM1,PDLIM5,FAM49B,CAMKK2,ATP2C1,ZNF605,MEGF11,ZMYND11,ARPP21,GALR1,ZNF559,LRRC37A6P,KIAA1841,MYOZ2,GATM,TUBGCP4,TUBA8,ARFIP1,SESN1,GGTA1P,GHR,PPARGC1A,MALT1,SPIN1,GLYR1,GLS,ZNF638,MAP7D2,DCLK2,GNAO1,PSRC1,TDRKH,GPR12,GPR34,GRIA1,DIDO1,GRIA4,RFFL,NR3C1,GRM7,FAM19A2,GYG1,RASSF8,HNRNPK,SMAP1,HTR2A,IRF8,MSL1,C5orf24,LRRCC1,PLD5,DIPK1A,INSM1,ITGAV,JAK1,SLC35G1,OLFM3,KCNJ3,KCNJ16,KCNN2,KIF5C,LINC00634,LAMP2,LMO2,SYTL4,HECTD2,ARHGAP12,NCOA7,PIK3AP1,MARK1,LYPLAL1,MAT2A,AQP11,MDM4,LRP1B,MEIS2,SRSF12,MEST,MITF,ZNF680,MSR1,NRBP2,MTTP,PABPC1L2A,NCAM2,NDP,NF1,NFE2L2,SLC11A2,SMIM11A,GPR88,GLIPR1L2,CNTN3,PCDH9,PDE1A,PDE1C,PDGFRA,PDPK1,GPR85,CYTL1,GPSM2,NLE1,ST8SIA5,PLCL1,PLIN1,PCDH18,LRP12,SCHIP1,SPATA6,CCDC144B,PPP2R5C,PPP3CB,PRKACB,PKN2,MAPK9,GRAMD1C,SNRK,MDGA2,PTK2,TMEM260,FAM120C,PTPRZ1,TTC13,ZNF615,MARCH1,RAP1GDS1,MSANTD2,SLC6A15,REV3L,FIGN,RFX4,TTLL7,ZFHX4,EXD2,CARF,RORB,FBXW7,ACER3,TCP11L1,MEG3,ABCA11P,KCNIP1,CLIP1,AP1AR,ATXN2,ATXN7,SCN7A,ELMOD1,TRA2B,HSPA4L,SCG5,ZFP30,SHMT2,HKDC1,MAGI3,FBXO11,FNDC3A,FHOD3,NLGN1,SEC31A,PAAF1,SLC1A3,PPP4R3A,RUFY2,RADIL,RAB3GAP1,TMEM132D,BTBD7,RCOR3,PDZRN3,UNC80,PDZD2,MYT1L,UHRF1BP1L,ZC3H13,SPTAN1,ZBTB43,SPART,COLGALT2,ITPRID2,SAMSN1,SMOC1,ERBIN,NXT2,ZSCAN29,SEPT8,NECAB1,FGD4,SYNE2,SLC37A2,CAMSAP2,FAM208A,KIAA1107,AGTPBP1,TBL1X,KLHL4,VWC2,SATB2,CUX2,TCF7L2,TCF12,CLASP1,DOCK9,PCDHB9,ARHGEF12,TEX15,RNF216P1,ZFPM2,AP4E1,RIMBP2,TP53BP2,TTC3,TMEFF2,SGK3,TUBB1,RPL7L1,FLRT2,CCDC14,NSD2,SLC13A3,SF1,ZBTB14,KCNT2,GPR158-AS1,SPIRE1,LAMP5,SMARCAD1,SYNC,SLC30A4,PRDM10,RNF103,HPS4,NAV3,KCNAB1,FAM47E,WNK3,DNAH10,FAM13C,RTN4,KAT6A,PHTF2,NLRP3,DPF3" MicroRNA hsa-miR-484:mirSVR_lowEffct hsa-miR-484:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.12E-142 6.26E-139 2.04E-141 1.88E-140 403 1846 "ABR,ACLY,SYS1,XKR4,CCDC85A,ADD1,ADD2,ADD3,AXIN2,KIAA1211,FAHD2CP,BEND6,ZNF608,OSBPL1A,OSBPL8,CARNS1,SYT13,ZNF687,AMPD2,AMPD3,CNTNAP1,UPRT,ALS2,BCAS1,TNRC6C,LGR5,SHROOM2,CADPS,CCAR2,ATP1A2,SLC4A4,STX16,SLC2A11,ADAM23,SNAI3-AS1,RGS9,NRP2,ZNF599,CFLAR,KSR1,CDK5R1,ARHGEF7,C5,GPC2,WASF1,CACNA1D,CALM1,KALRN,CAMK2A,CAMK2B,SPAG9,MAP7,CCKBR,KRIT1,METTL6,CD86,MYOM2,CDC25B,ZBED1,CDH8,EVI5L,IGFN1,CFL2,RCBTB2,CHGA,PLEKHB1,NDST3,RAB28,CLCN3,CLCN4,NMT2,TJP2,FADS2,IGLON5,CNTFR,IQCK,SLC25A27,COL11A2,BAG4,IGDCC3,CHD1L,CRMP1,HINFP,CSF1R,SEC24C,SUSD5,ATRNL1,PLCH2,CST3,CMTM5,PHF14,CFAP61,RUBCN,NOS1AP,ARHGAP32,GAPVD1,DCAF8,ZFYVE16,LIN54,MATR3,MAML1,PHYHIP,DGKG,SPOCK2,IP6K1,PABPC5,ARMCX4,PITPNC1,ZEB2,HEPH,CNIH3,COPS7A,C2CD2L,TMEM130,BLOC1S6,SV2A,SGSM2,WDR20,ZNF582-AS1,DLG2,EXOG,HS3ST4,HS3ST2,DNAH9,CD99L2,SHANK1,DPP6,ACOT8,PDCD6IP,DTNA,PHC2,FCF1,CNNM1,RBM12,YAF2,FAM13A,PHF20L1,EGFR,EGR3,TMEM132E,RASA4,GOLGA7,TENM1,TNK2,BSCL2,EPB41L2,ENPP6,ANKRD13B,MRPL10,NRN1,FAM198B,ATP8A1,ZNF589,GTF2IRD2,UBE2E3,MEX3B,IP6K2,AGAP2,SEMA4D,SORBS1,CAMKK2,DACH2,TBR1,GALNT15,ARPP21,ZNF234,DISC1,INPP5K,ARFIP1,GDF9,SESN1,GFER,GHR,KIRREL3,TXNL4A,GLI2,MSL3,INSM2,GPD2,TMEM121B,RAPGEF4,STMN2,GRB10,RFFL,ADAMTS13,PRDM5,GRM7,SOX21,GUCY1B1,TOX2,MAN1B1,LINC01102,SYNPO,HSD17B1,MSL1,MYLK2,ZIC5,TJAP1,IGSF1,INPP5B,SLC35G1,KCNK3,KCNMA1,GATD1,KHK,KIF5A,A1BG-AS1,LAMP2,STMN1,HECTD2,LOC100128239,MAT2A,SYT9,LDLRAD3,MDM4,MEIS1,MOG,ERICH3,DBNL,SAMD5,RSPO2,MYCN,MYH7,MYO7A,HNRNPM,NEUROD1,NF1,NOVA1,NUCB1,OGG1,P2RX7,P2RY1,PAK3,PCDH9,PCSK5,PDGFRA,GNG2,PFKFB3,SEMA5B,CAMKV,TMIE,PIK3CD,CCSER2,ZFYVE21,ANKRD16,PMP22,MAPKAP1,PRRX1,SDK2,SEPT4,MBOAT7,PPP1R1A,PTPA,NKAIN4,CEP41,EPDR1,MAPK10,HYDIN,GDPD1,MASP1,WBP1L,GON4L,MDGA2,CNTLN,ANKHD1,PTPRH,C1orf109,PTPRZ1,PEX5,TMEM231,MARCH1,ACSS3,RAD17,CCDC40,RALGDS,SUSD4,RAP1GDS1,RASGRF1,DBX2,SLC6A15,ZYG11B,RET,PRRT2,ERI2,RFX3,RIC8B,CYB561D1,KIRREL1,CCDC102B,RPE65,KIAA0895L,ADAL,MAP6D1,ATAT1,YJEFN3,KCNIP2,DGLUCY,SARS,SEMA6D,SCN3A,LINC00461,FNIP1,ASIC4,CASC3,FOXRED1,MRAS,FAM102A,ARX,SHC4,CHD9,FBXO11,FNDC3A,ST6GAL1,NUBPL,SMTN,SLC8A3,ARHGEF40,SLC9A5,SLC11A1,ELMO2,ATF7IP,EPC1,ABTB1,SMARCD3,SNCB,UNC80,USP33,PDZD2,TSNAXIP1,SPP1,DBNDD2,LHPP,TROVE2,POGZ,ITPRID2,ZC4H2,ZSCAN29,NEK4,STXBP1,AJAP1,PRRC2C,ZFR2,ARHGEF9,SYPL1,COBL,SYT5,WWC1,MGRN1,ANO4,TCF7,ZEB1,TRIM2,RPGRIP1L,SYNE1,NAT16,AKNA,RNF216P1,TF,GPR161,CDH22,ARL10,MTMR14,TMEM9,ACTR6,C5orf64,TNR,SMUG1,AMACR,TRPS1,ZMYND8,RUSC1,ZKSCAN5,LINC00689,PLEKHH2,VLDLR,BEST1,LAT2,GUSBP1,SF1,ZIC1,ZNF74,PLPP4,GPR158-AS1,NDRG4,SLC26A10,TMEM237,ZNF213,SLC30A4,ZXDA,PRDM2,CSDE1,PRDM10,HPS4,MPPE1,EPM2A,GOPC,KAT6A,HNRNPA3,FBXO36,CAMK1G,TRAM2-AS1,SLC39A12,SLC4A10" MicroRNA hsa-miR-515-5p:mirSVR_highEffct hsa-miR-515-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-142 6.67E-139 2.17E-141 2.00E-140 381 1656 "ABCF1,SYN3,ABHD6,NCKAP5,ADCY6,ADD3,CDC7,SORCS1,PLEKHH1,PWWP2A,ADRA1D,BEND6,DPY19L2P4,GPR158,SPOP,SRPX,CEP126,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APAF1,UPRT,ALS2,API5,SHTN1,PPP4R4,TMEM263,ZFYVE28,CDK13,ASCL1,ASPH,ZBTB10,CHRD,NCOA1,ATM,ATP1A2,SLC4A4,ATP1B3,ALDH7A1,B3GALT2,DPY19L3,ADAM15,NRP2,ZNF599,CFLAR,BMPR1B,SYNJ1,ARHGEF7,CACNA1A,CALB2,CALM1,PTBP2,CAST,HIP1R,SPAG9,CD38,CDC42,CDH18,LGI1,L3MBTL4,CDO1,CLGN,CHM,SYNPR,B4GALT6,IGFBP7-AS1,COG1,ABCG2,QKI,MAP4K4,AKAP6,SLC4A7,SLC4A8,CHD1L,CREB5,NCOR1,CS,SNCAIP,FEZ2,VAC14-AS1,PDE4DIP,PLXNA4,DZIP3,UBXN2A,PUM1,RIMS2,USP6NL,CCDC144A,NOS1AP,DOCK4,GPRASP1,ARHGAP24,MATR3,PABPC5,ARMCX4,DNAJC6,HP1BP3,COPS7A,C2CD2L,CEP170,DDX46,RHOBTB1,SNAP91,SACS,G3BP2,RABGAP1L,CCDC3,CHRDL1,DLG4,DMD,USP3,CPEB2,DMTF1,DRD1,ABCC9,GOLT1B,EDN1,EDN3,HIPK3,SEMA3D,EFNA3,YAF2,FAM13A,KMT5B,GOLGA7,ASB3,EIF4G2,COPS4,TENM1,ELAVL2,RGS17,PAN3,LRRC17,RASGRP2,ENPP6,DENND4A,ETV1,EXTL2,ADGRV1,CLVS1,ACSL4,TAOK3,RACK1,CEP78,GORAB,SEC24B,FER,KIAA1109,FGF12,IP6K2,PCYOX1,SYNCRIP,RGPD5,FOXO3,SEMA4D,ATP13A4,SGIP1,TMEM107,SPECC1,PDLIM5,ATP2C1,ZNF605,MSANTD4,NRG3,OGA,SDCBP2,MEGF11,HRASLS5,GABRB1,GABRB3,CAB39,ARPP21,DISC1,ATP8A2,ACSS1,MYOZ2,TUBGCP4,SULT1C4,MSTN,GHR,PPARGC1A,COPS8,HPGDS,DBF4,TNRC6A,ZNF638,CBX1,MAP7D2,LUZP2,GPD2,TDRKH,GRIA1,GRIA2,GRIA4,GRIK1,NR3C1,GRM1,GRM5,LINC01551,AP4S1,MAEL,HAS2,PTGDR2,LINC01102,MIER3,HNF4G,SMAP1,MSL1,C5orf24,LRRCC1,PLD5,USP54,BRINP3,DIPK1A,ZNF385B,KCNA4,KCND1,KCND2,KCNJ5,KCNK2,KCNN1,KIF2A,KLC1,CYP27C1,CAMK2N2,HECTD2,MAOB,MBD1,KCTD6,MITF,MN1,ZNF680,ADAM22,ZNF92,CTNNA3,NACA,BEX5,NAP1L1,NCAM2,NDUFA5,NF1,DNHD1,NPTX1,SETD4,OPA1,CLDN11,SNTG1,PAK3,PRTG,PDE1A,PDE3B,PDGFRA,CDK14,NALCN,SEMA5B,PIK3R1,ZNF655,ZFYVE21,XRN1,MAPKAP1,FSD1,PPARA,MED1,CRLS1,PPP2R5C,PKN2,EPDR1,GRAMD1C,CNNM2,SLC22A23,GDPD2,PSMD13,MTMR10,PTN,TMEM260,OCIAD1,PTPRD,PTPRG,PEX2,CEP97,ZNF793,SUSD4,ZNF493,RBBP6,RDX,SLC6A15,RFX4,RGS12,SEC61A2,RERGL,EXD2,ALG9,RAVER2,CARF,GSTCD,RPE,NEK11,SPIN3,ATP8B4,TCP11L1,ABCA11P,RTKN,KCNIP1,NCBP3,AP1AR,SCN4B,SCN8A,FNIP1,CASC3,ITSN1,FAM102A,HKDC1,FBXO11,SLITRK3,ST3GAL3,WDR37,ZNF365,EPN2,RUFY2,SLC8A3,ARHGEF40,SIRT2,SMARCE1,RCOR3,MBD5,ZNF415,TMCC1,FAM126B,BDP1,KIF1B,RBM26,SPART,C11orf87,SRPK2,TAB2,POGZ,NKAIN2,DIP2A,AJAP1,VPS13A,DDHD2,CAMSAP2,TPCN2,TRIM2,TCF12,SYNE1,PCDHB6,FRYL,C18orf54,ITGB3BP,AP4E1,TPM1,NPL,TPM3,RGMB,ZMYND8,TSC1,PRR18,FRRS1L,VSNL1,ZNF708,ZNF19,GPR158-AS1,ZNF154,ZNF177,INTS3,WNK1,ZXDA,CADM2,PRDM2,ADAMTS9,CIAPIN1,NAV3,KCNAB1,PDSS2,RGS7BP,DNAH10,PAK5,ZNF248,SSPN,NETO1,DPF3" MicroRNA hsa-miR-578:mirSVR_highEffct hsa-miR-578:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.31E-142 7.35E-139 2.38E-141 2.19E-140 402 1838 "KCNH8,ACADM,KDM5D,ADAR,DSCAML1,RNF157,ADD3,NLGN4X,PCDH19,KCTD16,HFM1,SPOP,CEP126,ABCD2,ARHGAP20,FAM135A,ZFAT,LRCH2,ANK3,LCORL,MAP4K3,PPFIA1,GPAM,ALS2,SHTN1,CDC14B,ARNTL,RGS20,STK33,NUMB,DDX3Y,ATP2A2,DPY19L3,TTLL9,MPDZ,SEC11C,NRP2,CFLAR,DST,SYNJ2,CA12,KALRN,PTBP2,CAMK2G,CAST,RUNX1T1,NFS1,ZNF501,LDB2,KRIT1,ZBED1,KCNAB3,LGI1,MAGI1,ADGRG1,RCBTB2,SRSF11,CHN2,CASC2,JAM2,NDST3,LSMEM2,ZFYVE9,PLAA,KIAA1549L,NRXN1,C4orf33,NIPBL,FAM149A,ABI3BP,BAG4,ACBD5,ZFP28,CP,CHD1L,CREM,AKAP12,CRMP1,CSF2RA,ARHGEF10,VCAN,PDE4DIP,UBXN2A,PHF14,PNPLA8,GREB1,ARHGEF4,NRSN1,CYBB,HDAC9,GAPVD1,FRMPD4,ZFYVE16,CENPL,LONRF1,TM9SF4,MATR3,KIAA0586,KCTD8,PABPC5,PITPNC1,ZEB2,HP1BP3,KIAA0753,BLOC1S6,PLPPR4,SPOCK3,WDR20,EXOG,GRIN3A,DMD,NR1D2,CPEB2,ABI1,ATN1,DYRK1A,ABCC5,DNM1L,ABCC9,E2F5,EDN3,HIPK3,KLHL5,OPTN,SUGP2,MRO,EPB41L2,RCAN2,EPHB1,ENPP6,RABEPK,SRRM1,F5,FAM198B,WAC,CACNG2,ACSL4,FER,KIAA1109,FGF11,FGF12,BAIAP2,FOXG1,SYNCRIP,FLT1,C2orf88,TACC2,SORBS1,SMC2,APOPT1,DACH2,AP4B1,NRG3,ABLIM2,FYB1,STAG2,GABRA1,HBS1L,GALR1,TMEM8B,SIGLEC8,ZNF559,LRRC37A6P,GCNT2,MSTN,SESN1,GFAP,ADAM28,PCDH17,MALT1,BRD8,GLI2,TOX3,PCDH11X,MAP7D2,ZNF782,LNX1,WDFY3-AS2,GPM6A,LPAR4,RAPGEF4,RAPGEF1,GRIA2,GRIA4,GRID1,GRIK2,NR3C1,PRDM5,CIT,CLASRP,SOX21,WIF1,RASSF8,HAS2,UBE2QL1,PADI2,NXPH2,HMGCR,NEGR1,IRF8,LRRCC1,DISP2,SCIN,DIPK1A,NME9,ITGAM,KCND2,KCNJ10,KCNJ16,KCNK2,STXBP5,VWA5A,HECTD2,NCOA7,MARK1,LYPLAL1,MAT2A,MATN2,SYT9,MDM4,MEIS2,KCTD6,MITF,XRRA1,WDR49,MOBP,MTTP,MXI1,NASP,NCAM1,NF1,NPTX1,NTRK3,NUCB2,OGG1,GLIPR1L2,CNTN3,PAX6,PCSK2,PDE1A,PDE4D,GNG2,CDK14,PIK3C2A,RETREG1,NLE1,PLCL1,PLP1,PCDH18,PRIMPOL,PMP2,STRN3,PRRX1,SDK2,ING3,SEPT4,PPP2R5C,PPP3CA,RAB39A,MAPK9,HYDIN,DCHS2,MDGA2,PTCH1,BDNF-AS,PTK2,TMEM260,OCIAD1,PTPRE,ACSM5,CEP97,USP47,RAD17,PLEKHB2,FAT4,RASGRF2,ARID4A,DBX2,RDX,ZYG11B,RLBP1,NUDT11,RPRD1A,SETD5,CARF,CCDC25,RORB,MRAP2,NEK11,FBXW7,BAALC,ATP8B4,CNTNAP3,ABCA11P,ATAT1,RYR3,ZNF331,TNFRSF19,ELMOD1,TRA2B,SCAF8,ITSN1,PPM1E,CPEB3,MAGI3,FHOD3,CTXN2,ANKRD6,PAAF1,ZNF365,RUFY2,RAB3GAP1,CPEB4,SMARCA4,OGDHL,SMARCE1,MBD5,KIF13A,MYO16,UNC80,SON,SOX2,CAND2,IDI2-AS1,KIF1B,ZBTB43,RBM26,LARP4,TTBK2,RGL1,JMJD6,ARHGEF9,VPS13A,SYPL1,COBL,KAZN,EXOC7,ADGRL3,TBCEL,ANO4,ATMIN,VWC2,CLASP1,DOCK9,PCDHB9,PCDHB3,AKNA,PUM2,GPRIN3,FRYL,AHCYL2,AP4E1,TGFBR3,MTMR14,HEY1,ERCC6L2,FAM124A,CSMD1,ZNF384,PRMT8,TRO,TRPC1,ZMYND8,TMPRSS5,CLHC1,SGK3,TUBB1,FLRT2,USP1,CCDC14,WIPF1,SLC13A3,ETNPPL,ZBTB14,ZNF23,ZNF24,MICU3,KCNT2,TRIM9,AGMO,ZNF74,LYPD6,ZNF138,FSTL5,ZFAND5,UPF3A,WNK1,PRTFDC1,SLC38A1,VPS35L,PCDH15,CAB39L,WNK2,SLC17A6,PDSS2,EPM2A,FZD3,RTN4,TRAM2-AS1,ZNF248,TIGD6,MSRB3" MicroRNA hsa-miR-497*:mirSVR_highEffct hsa-miR-497*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-142 7.96E-139 2.57E-141 2.37E-140 349 1393 "ARID1A,NDRG3,KLHL32,KIDINS220,DPY19L2P4,NLGN4X,GPR158,TBC1D14,OSBPL6,OSBPL8,SPARCL1,SMIM17,PDZD4,DPP10,LRCH2,ANK2,LCORL,PHF12,ALS2,BCAS1,PPFIA3,APP,TMEM263,IGDCC4,ASCL1,ASPH,CCAR2,DDX3Y,TMEM108,ATP1B3,ATP2A2,ATP2B2,RNF182,ADAM23,MPDZ,CDK5R1,FUBP1,AP1M1,OSGIN2,CA8,CA12,SLC25A14,SYT6,BRSK2,CD38,NEURL1,LRBA,SEPT7,CDH2,CDH8,MAGI1,CLGN,CACNA2D2,COPB2,CHM,NRXN3,NMT2,ABCG2,IQCK,BTF3L4,SLC4A8,MYRIP,MFSD4A,CP,SLC35F1,SEC31B,CREM,ENTPD4,NCOR1,GDA,ABCG1,LRRC3B,ATRNL1,PHF14,NRSN1,HDAC9,ARHGAP32,LONRF1,DGKB,DAPK1,ZEB2,TIAM2,CEP170,SMG7,PLPPR4,SNAP91,KIF19,NR1D2,CDON,CPEB2,DMTF1,ABI1,PDCD6IP,RCAN1,DTNA,DNAJB6,DYRK1A,ABCC5,GOLT1B,EDNRA,FSD1L,OPTN,YAF2,PHF20L1,KCTD3,EIF4G2,TMEM35A,RCAN2,EPHB1,KCNMB2,MRPL10,RTN3,EXTL2,ABCA8,FAM198B,DLC1,CEP78,GORAB,MED12L,FGF12,FGF13,BAIAP2,POLK,FOXF2,IP6K2,PCYOX1,JKAMP,USP16,STAMBP,ATP6V1H,AP4B1,NRG3,FYB1,CHL1,CAB39,GAD1,ZMYND11,GALC,RAPGEF6,SALL3,ARFIP1,ADAM28,GFRA2,GHR,PPARGC1A,KIRREL3,GK,ZNF276,CRCP,SPIN1,GLS,ZNF638,PSRC1,GPM6A,GPM6B,GPR12,LPAR4,CNTRL,RAPGEF4,STMN2,GRIA4,GRM1,GRM2,GUCY1A2,ELOVL5,HMGB1,HNF4G,HNRNPK,HP,HPR,SOWAHA,RBPJ,IL6R,ZNF678,ITGA7,ITIH2,OLFM3,KCNA6,KCNB1,KLRC2,STXBP5,MARK1,MARK3,MBNL1,MDM4,MRPL42,THYN1,MYCN,PABPC1L2A,NAP1L3,NELL1,NEK1,NEUROD1,NF1,NPPA,NRCAM,P2RY1,PAH,GLIPR1L2,CNTN3,DPY19L2P2,PCMT1,SLC10A4,GPR85,PFKFB2,CDK14,A2ML1,PLP1,SMIM7,HMGCLL1,PMP2,LRP12,PSAT1,EPB41L4B,IRX1,MED1,TATDN3,PRKACB,PKN2,MASP1,SIDT1,MDGA2,CNTLN,PTHLH,ZSCAN32,PTPRB,OCIAD1,PTPRD,PTPRE,C1orf109,RAD17,SH3TC2,ZNF493,DBX2,RADX,SLC6A15,ERI2,RGS12,KIF7,RIT2,NUDT11,CCDC82,GSTCD,MRAP2,RPL15,FBXW7,ZC3H14,CNTNAP3,LGR4,WLS,RTN1,CCDC112,SEMA6D,SCN7A,LINC00461,SUPT20H,ZFP30,KIF21A,ITSN1,FERMT1,CPEB3,FHOD3,BTBD3,EPN2,WDR47,SLC6A11,ELMO2,SLCO1A2,SPHKAP,ZFP1,SORCS3,SMARCE1,RCOR3,SNAP25,UNC80,WDTC1,ENKUR,KDM4C,TEX2,NPAS3,ATP10B,CLSTN2,LARP4,SS18,CEP68,GANAB,FGD4,VPS13A,PLCB1,SYPL1,DDHD2,TBCEL,TCF4,ZEB1,RPGRIP1L,WASHC4,PCDHGA11,SYNE1,DOCK9,RALYL,PCDHB10,PUM2,FRYL,SIK3,CYB561A3,TEK,DICER1-AS1,C18orf54,ITGB3BP,AP4E1,AKTIP,TIAM1,HEY1,ASXL3,HEY2,TP53BP2,SYNPO2,TRH,STXBP4,ANO5,HIRA,UCHL1,USP1,CCDC14,WIPF1,CLDND1,RICTOR,XPO1,SF1,ZIC2,ZNF17,MICU3,ZNF28,FMN2,FSTL5,UPF3A,SLC30A3,ZXDA,CADM2,RNF103,SLC17A7,C12orf4,GOPC,FAM13C,MRPL47,RTN4,PHTF2,MSRB3,SSPN" MicroRNA hsa-miR-135a:mirSVR_lowEffct hsa-miR-135a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-142 8.88E-139 2.86E-141 2.63E-140 408 1892 "DPF1,SERPINA3,NCKAP5,SYS1,FMNL2,ADARB2,KLHL32,TMEM132B,GALNT16,ADCY2,ADD1,ADD2,PWWP2A,BEND6,OLMALINC,SLC44A5,GPR158,HACE1,OSBPL8,PLA2G6,SEMA6A,ARHGAP20,UNC79,ZFAT,CDC42BPA,ANK1,EP400,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APBA2,ALS2,PRX,CAPRIN2,NCOA1,DDX3Y,ATP2B2,ZNF582,ZNF583,MTMR9,DPY19L3,LINC00847,HCN2,SYNJ2,MTMR2,GYG2,BSN,CFAP410,CACNA1E,CAMK2D,TRIM41,VXN,NFS1,SHISA7,METTL6,P2RX6,CD86,ZBED1,CDH8,LRRFIP1,LGI1,MAGI1,CDO1,CCPG1,FOXN3,CHM,CASC2,JAM2,NDST3,CPNE6,IGFBP7-AS1,CLCN3,SLC24A2,TJP2,RAB26,CNGA3,TMEM155,IQCK,PCYT1B,AKAP6,SLC4A7,SLC4A8,ABI3BP,MYRIP,HS3ST5,ZNF385A,SLC35F1,PNKD,CREB5,RNF14,NCOR1,GDA,SNCAIP,CSF1,PPP1R16B,PHF14,GREB1,ARHGEF4,RIMS2,DOCK4,KATNAL2,GAPVD1,RIPOR2,DCAF8,TOX,PHF19,DBI,ARMCX4,ZEB2,PLEKHM1,RUSC2,C2CD2L,RHOBTB1,SACS,SV2B,NTM,RABGAP1L,WDR20,DLG2,DYNC1I1,DNM2,DOCK2,DMTF1,SLC12A6,DPH1,CASP8AP2,SLC25A18,DRD1,ACOT8,DRP2,DTNA,FAM78B,WDPCP,EDN1,ATL1,FCF1,MRO,KMT5B,AASS,LPAR6,COPS4,RGS17,DCTN4,EIF1,EPB41,APC2,VPS26C,DNAJC27,SIRPB1,EXTL2,WAC,ATP8A1,CEP78,FCGR3A,GORAB,FER,AMOTL2,IP6K2,RGPD5,FLT1,SYT3,C2orf88,NSG2,DACH2,STAG2,MEGF11,HRASLS5,CHL1,GABRG1,GAD1,AHCYL1,ZMYND11,B4GALNT1,RAPGEF6,GALR1,SALL3,ZNF274,DISC1,CPLX1,FAXC,CYP46A1,LYVE1,GK,RNPS1,HPGDS,DBF4,TOX3,PCDH11X,STARD3,ZNF638,DCLK2,LNX1,ADGRA3,LILRB4,PRUNE2,GPR22,NUDT21,PCLO,GRIA2,GRIN1,BTN2A1,KIF3A,BVES,ADAMTS6,MAP4K5,RASSF8,ZHX1,ARHGAP19,INSYN1,MIER3,HNRNPK,NEGR1,AGFG1,SHISA6,MSL1,GAREM2,RBPJ,LRRCC1,KCNB1,KCNC1,KCNJ3,KIFC3,KIT,CYP27C1,KTN1,HECTD2,MAP4,MARK1,MAT2A,MATN3,MEF2C,MEIS2,MEST,KCTD6,MID1,PPM1L,POC1B,MN1,WDR49,MOBP,MOV10,SAMD5,RSPO2,HS6ST3,NEUROD1,NF1,ALDH1L2,DNHD1,NUCB2,ODF2,OMG,GPR137C,PRTG,PDE1A,PDE2A,PDYN,GPR85,SSH1,PIK3C2A,ZNF655,CCSER2,SNX10,GPSM2,ST8SIA5,PLXNB3,ANKRD16,TNPO2,FAT3,KANSL1,CEP41,SNRK,WDR25,CNTLN,UHRF1BP1,BDNF-AS,PTPRE,FAM120C,SH3TC2,OXR1,RASGRF2,RBBP6,BSDC1,MSANTD2,ZYG11B,REV3L,PRIMA1,TTLL7,SEC61A2,RIC8B,SETD5,RAVER2,GSTCD,ROBO2,SPIN3,ZNF671,MCMBP,ATP8B4,GLDN,ACER3,TCP11L1,SEMA6D,SCN2B,FAM19A1,LINC00461,SCP2,ELMOD1,MRAS,SUPT20H,ITSN1,FAM102A,HKDC1,NLGN1,DZIP1,CLSTN1,SLC1A6,FAM81A,SLC8A2,SHANK2,KBTBD4,ELMO2,ATF7IP,SLN,SMARCA4,SORCS3,RCOR3,MAPKBP1,UNC80,USP33,SCN3B,WDTC1,MYT1L,TRERF1,SOX2,KIF21B,NMNAT2,GLT8D1,TEX2,DBNDD2,KIF1B,IQSEC2,C11orf87,ATP10B,ZC4H2,CEP68,FGD4,JMJD6,PRRC2C,ZFR2,VPS13A,PLCB1,COBL,DDHD2,CAMTA1,DNMBP,UNC5D,TCF4,TCF7,ZEB1,RALYL,ARHGEF12,PCDHA5,AHCYL2,DICER1-AS1,ZFPM2,GPR161,THBS4,TIAM1,MTMR14,TLL2,TNS1,RBFOX2,TPM1,PRMT8,NEIL2,STXBP4,FNDC5,RUSC1,ANO5,UBE2H,OSBP2,PLEKHH2,NSD2,SLC13A3,ZIC3,ZNF28,ZNF154,EML6,SPIRE1,SMARCAD1,SYNC,PRDM2,SLC38A1,CSDE1,ADAMTS9,HPS4,FAM47E,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,CASC15,NUP214,CERS6,ACTR3B,TRAM2-AS1,MSRB3,CBLN2,SOCS4" MicroRNA hsa-miR-620:mirSVR_lowEffct hsa-miR-620:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.03E-142 1.14E-138 3.65E-141 3.36E-140 382 1667 "SERPINA3,CLK4,C3orf14,NCKAP5,SYS1,ACTN1,SLC12A5,USP31,KIAA1211,DPY19L2P4,SLC24A4,AP2A2,WDR35,OSBPL8,AK2,SEMA6A,ALCAM,PCDH10,ANK2,SUGT1P4-STRA6LP-CCDC180,ALS2,CACHD1,APP,SHTN1,LGR5,SFMBT2,ARHGAP5,MARK4,ASPH,ASTN1,ATM,EIF4G3,ATP2B2,SLC2A11,ADAM15,BACH1,LINC00847,RGS9,CFLAR,BTK,CACNA1G,BSN,RAB29,CDK5R2,CACNA1D,CACNB2,ZNF555,PTBP2,CAMK2D,VXN,SPAG9,CCNH,P2RX6,TMEM257,C1orf52,REPS2,CDC27,ZMYM4,LARGE1,TIGD7,CCPG1,NUMBL,SYNPR,RAB28,TPP1,STOML1,FBXO7,QKI,SRP14-AS1,HECTD1,FAM149A,COL4A5,TOGARAM2,CLOCK,PREPL,CREM,CREB5,SLC32A1,SNCAIP,CSF3R,ATRNL1,ERC2,APPL1,UBXN2A,CTNND1,RUBCN,TCAF1,ZFYVE16,TBC1D5,DGKB,GIT2,DCC,C8orf34,ZEB2,CEP170,MAGI2,KLHL3,BLOC1S6,POM121,SMG7,SV2B,NTM,ARNT2,DLG2,DLX1,GRIN3A,USP3,DYRK1A,FAM135B,PHC2,RASGRP1,EGFR,RASA4,ELN,KCNMB2,SRRM1,ERBB4,MRPL37,DUSP27,SIRPB1,MRVI1,CACNG3,FCGR3A,FCGRT,FKTN,FDFT1,FER,GTF2IRD2,POLR1B,SUCO,PCYOX1,ATP13A4,ANKFY1,NOP56,SORBS1,PDLIM5,ATP2C1,PNMA2,SARAF,STAG2,HRASLS5,GABRA5,GABRB3,CAB39,GAD1,ERAP1,ATP8A2,ACSS1,TUBGCP4,SESN1,ADAM28,GHR,BRD8,GLS,TOX3,AIFM3,CBX1,DCLK2,PRUNE2,GPR22,PCLO,PLCD4,CIT,FAM107A,GUCY1A1,MAEL,IGSF21,LINC01102,HSD17B1,HSF2,HTR5A,KIAA1755,DISP2,IL11RA,SLC35G1,CDH20,KCNJ9,KCNN2,CREG2,STXBP5,INSYN2,PIK3AP1,GPR155,MAP4,MAT2A,MBD1,CHIC1,MDM4,MEF2C,KITLG,PPM1L,MOG,JAKMIP3,NEXMIF,ZNF862,NCAM1,NDUFA5,NEUROD1,ALDH1L2,VWA2,NOS1,CNOT4,NOVA1,LRIT2,PCBP3,TBC1D25,OLR1,OPHN1,KCNK10,PAK3,PCSK5,PDE1C,PDE3B,GNG2,PFKFB2,PFKFB3,NLGN3,NALCN,PIK3C2A,ZNF655,CCSER2,PCDH18,PMP22,MAPKAP1,PILRA,PTPA,PPP2R5C,PPP3CC,RASGEF1B,PKIA,DCHS2,MASP1,RELN,BCAS3,PSMD13,CNTLN,OCIAD1,FAM120C,TMEM145,ZSCAN2,TUG1,RAB5B,CEP97,FAM66C,RALGDS,IQSEC3,FAM184A,ARID4A,RBBP6,KHDRBS2,ZMAT4,ERI2,ARHGEF10L,SUGCT,ALG9,ROBO2,CCDC102B,UEVLD,FBXW7,WLS,KCNIP1,TRAPPC13,AP1AR,SALL1,ATXN1,SCN4B,LINC00461,SEC14L1,SOX6,SCAF8,SH3BGR,FHOD3,PAAF1,BTBD3,KANSL3,SLC6A8,SLC8A3,KBTBD4,NAPB,MTERF2,BTBD7,EPC1,ZNF667,SMARCA4,MAST1,CDK5RAP2,ANKRD36,MBD5,CABCOCO1,FAM126B,DOP1A,SOX2,KIF21B,BDP1,SP4,UHRF1BP1L,ZC3H13,SPTAN1,KIF1B,CDK19,TROVE2,ITPRID2,ZC4H2,NKAIN2,INKA2,RGL1,ACSBG1,VPS13A,C3orf70,COBL,SLC37A2,ANKRD12,MTCL1,PJA1,WWC1,TBL1X,KLHL4,SIN3B,DMXL2,SATB2,TPCN2,TMEM151B,OBSL1,PCDHAC2,PUM2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,HHIP,AKTIP,ENHO,MTMR14,DAAM2,RIMBP2,NPL,C9orf85,SYNPO2,FNDC5,TSN,ANKRD20A2,TSC1,TMEFF2,SGK3,HEPACAM,RPL7L1,AMOT,BCL2L13,VAV2,TBC1D15,LMF1,TSPAN11,WIPF1,CLDND1,SF1,ZIC2,FMN2,SPIRE1,SMARCAD1,SLC38A1,CSDE1,ADAMTS9,HPS4,URM1,SLC17A7,SNX27,MVB12B,PDSS2,UBE3B,SMIM8,CASC15,NUP214,FAM219B,TRAM2-AS1,VANGL2,ST8SIA2,SENP7,JPH3" MicroRNA hsa-miR-924:mirSVR_lowEffct hsa-miR-924:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.05E-142 1.15E-138 3.67E-141 3.38E-140 389 1727 "RALGAPA1,TTYH1,SDE2,ABR,ACADM,AS3MT,NCKAP5,SYS1,ARID1A,CSMD3,KLHL32,CDC7,PLEKHH1,SLC24A4,GPR158,CC2D2A,LRRC7,ALCAM,SRPX,FAM135A,CDC42BPA,FGD2,PHF12,PPFIA1,APC,CACHD1,API5,AQP4,CDC14B,PPP4R4,TMEFF1,CDK13,ATP1A1,EIF4G3,ATP1B3,SLC2A11,MPDZ,LDHD,BMP7,BMPR1B,ST3GAL5,SCAPER,GPC2,OSGIN2,WASF1,LDLRAD4,CA8,CA12,CACNB4,KALRN,CAMK2D,CAMK2G,VXN,SYT6,CH25H,KRIT1,SLC16A4,CBFA2T2,DGKI,SRSF11,CHGA,ASIC3,SLIT2,TPP1,QKI,MAP4K4,ARHGEF6,CNTN1,COL4A5,SLC4A8,TBPL1,AHCTF1,ZNF521,C2CD2,CREB5,NCOR2,CS,FEZ1,ATRNL1,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,UBXN2A,PHF14,ZSCAN23,SEC14L5,BOC,KATNAL2,TOX,TBC1D5,RIMS3,ARMCX4,ARMCX2,ZBTB24,MFAP3L,CEP170,DDX46,TMCC2,FAM107B,DLX1,OLIG1,ACOT8,DYRK1A,DNM1L,EDN1,FAM135B,EDNRB,RBM12,EFNB3,GPR61,APH1A,EGR3,IRAK4,STARD3NL,EPB41,RCAN2,LRRC17,RASGRP2,GPHN,ERBB2,IGSF6,KATNAL1,F3,ARMCX1,CLVS1,EFEMP1,ST3GAL6,ZSCAN30,GTF2IRD2,FGF13,BAIAP2,PRKAG2,FOXO3,ATP13A4,SYT3,JKAMP,POMT1,TMEM107,USP16,FAM49B,ARFGAP2,KHDRBS3,CELF1,STAU2,B3GAT1,ADGRA1,AP4B1,NRG3,OGA,NEK6,ERAP1,ZNF559,C15orf41,KIAA1841,MYOZ2,SULT1C4,MSTN,CYP46A1,GFRA1,PPARGC1A,GNAO1,FERMT2,TDRKH,PCLO,GRIN2C,GRM7,BVES,MFSD2A,SOX21,GUCY1A2,ADAMTS6,GUCY1B1,GYG1,RASSF8,TNFAIP8L3,ARHGAP36,HNMT,TLX1,CPT1C,LRRC75A,SHISA6,IGF1,ZIC5,RBPJ,LRRCC1,PLD5,IL6R,JAK1,KCNB1,KCNF1,KCNN2,LAMA2,LIMS1,HECTD2,ARHGAP12,PIK3AP1,ZFYVE27,MAP2,MARK1,MAT2A,IL17D,MDM4,LRP1B,SHC3,XRRA1,MOG,CCDC80,MT3,TAGLN3,MYL3,NEXMIF,FXYD6,P2RY13,NCAM1,NELL1,CCDC13,NFE2L2,NOVA1,DNHD1,SMIM11A,NTRK2,OCRL,P2RY1,GLIPR1L2,PAK3,PDCD2,PDE3B,PDE4A,GPR85,CDK14,ZFYVE21,RETREG1,XRN1,JAKMIP1,FTO,PCDH18,ANKRD16,RC3H2,DRAM2,PPP2R5C,PPP2R5E,KANSL1,RASGEF1B,PRKACB,MAPK9,GRAMD1C,LRRC49,TMEM104,TMEM260,PTPRB,PTPRZ1,PTX3,TUG1,TMEM231,ACSS3,CCDC40,FAT4,ROGDI,VEPH1,KHDRBS2,MSANTD2,ZYG11B,ZMAT4,RGS4,TTLL7,PBRM1,TMLHE,ROM1,GLDN,SGSM1,ATAT1,KCNIP2,ATXN2,SCN7A,SCP2,TNFRSF19,ELMOD1,SEC14L1,SUPT20H,NLGN4Y,ITSN1,NTNG1,MAGI3,SLITRK3,PPP4R3A,SMTN,YPEL4,SEPHS1,ARHGEF40,SLC14A1,BTBD7,ZNF667,MYH15,ANKRD36,SNRPN,UNC80,SCN3B,DOP1A,SON,SOX11,UHRF1BP1L,ZNF423,TSPYL2,NFASC,C11orf87,ZNF621,ATP10B,PBLD,CLASP2,NXT2,SEPT8,STXBP1,SYT11,PLCB1,SYT1,CAMTA1,FAM208A,UNC5D,KIAA1107,TMEM136,ATMIN,TCF7L2,RPGRIP1L,WDR7,FAM189A1,SLC19A3,PCDHB4,FRYL,HIF3A,CYB561A3,DNAH7,PMS2CL,ITGB3BP,HHIP,HEY1,ACTR6,BHLHB9,TMOD1,DAAM2,FAM124A,TP53BP2,RBFOX2,SEZ6L,CHST5,ZNF346,SYNPO2,SMUG1,TSC1,SSBP2,TTTY15,TMEFF2,TUBB1,HEPACAM,CADM1,UBE2H,AMOT,MTCH1,RICTOR,GUSBP1,LGI4,ZIC3,ZNF19,ZNF24,MICU3,KCNT2,CFAP52,ELFN1,MKRN3,CELF4,EMSY,PRDM2,PRTFDC1,LRP8,LINC02210,STOX2,RNF103,NAV2,SLC17A7,FIP1L1,LINC00632,WIPF2,HRASLS,ST7,SNX14,SLC39A12,RNF146,SLC4A10,LAS1L" MicroRNA hsa-miR-1178:mirSVR_lowEffct hsa-miR-1178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.00E-142 1.68E-138 5.36E-141 4.94E-140 376 1618 "CPNE2,RALGAPA1,FMNL2,KLHL32,ADCY2,AXIN2,ERMN,FZD9,KIAA1211,SLC24A4,AP2A1,ZNF608,KLHL13,AGT,CC2D2A,HFM1,C1QTNF3,LRRC7,CEP126,AMPD3,ANK2,EP400,PPFIA1,ALS2,SHROOM2,TMEFF1,RGS20,ARRB2,DDX3Y,SLC2A11,BACH1,MIR9-3HG,DST,ARHGEF7,OSGIN2,CALB1,THSD7A,CALM1,KALRN,CAMK2D,VSTM2A,BRSK2,RHBDL1,CBR1,AIFM1,SCARB1,ENTPD6,CDK11B,CDC25B,CDH8,LRRFIP1,L3MBTL4,CLGN,NOG,UBE2L6,CHN2,SYNPR,CHRNA4,LHX2,FBXO7,C4orf33,NIPBL,TMEM155,COL4A5,COL9A2,MYRIP,CNRIP1,CLOCK,CDC42BPB,PREPL,RBM39,CRY2,GDA,TRIM69,RGS6,SEC24C,PDE4DIP,FAM169A,DZIP3,GREB1,ARHGEF4,CCDC144A,BOC,HDAC9,GAPVD1,RIPOR2,KIAA0586,DAPK1,TOMM20,DNAJC6,JAKMIP2,PLEKHM1,MYEF2,C2CD2L,KIAA0319,MED24,BLOC1S6,DDX46,SMG7,SV2B,SRGAP3,RABGAP1L,TMCC2,DLG2,GRIN3A,HS3ST4,SLC29A4,TRAPPC9,NR1D2,DNM2,DRP2,DTNA,SEZ6L2,FAM135B,KLHL5,FRY,EFNB3,CELSR3,EGFR,KMT5B,KCTD3,EIF5,ELAVL2,RCAN2,ANKRD13B,STX2,RTN3,DNAJC27,ANKMY1,SIRPB1,EYA1,EZH1,FAM198B,WAC,ATP8A1,FCGR1B,TOMM40L,KAT8,SPSB4,FGF12,FHL1,POLK,SUCO,IQCG,FOXO3,PSD2,STAU2,PNMA2,DKK3,GAB1,GABRG1,GAD1,AHCYL1,B4GALNT1,MTHFD2,ZNF559,INPP5K,LRRC37A6P,KIAA1841,DNER,NEU3,GGT7,ZNF276,RAB30,KIAA1958,OS9,INSM2,GNAL,ZNF782,ADGRA3,GPM6B,DIPK1C,NUDT21,TMEM121B,PCLO,GRM5,GRM7,LINC00839,FAM19A2,PTPN5,RNFT2,ADAMTS6,NCKAP1L,ATXN2L,MIER3,HNMT,SHISA6,SOWAHA,GAREM2,RBPJ,IGSF1,ITPKB,KCNA4,KCNA6,IPO5,SYTL4,MAG,LOC100128239,SYT9,LRP1B,MEF2C,SCAMP5,PPM1L,MN1,GIT1,N6AMT1,MYO7A,RTL5,ZNF862,NEFH,NEUROD1,NEUROD2,NFIA,NHLH1,NODAL,NOS1,DNHD1,HCN1,IGSF11,LOC100128398,PCSK5,PDE2A,HERC2P3,CCSER2,FTO,SMIM7,ZNF426,MTRF1L,PRIMPOL,ING3,EPB41L4B,TMEM235,MED1,PPM1B,TATDN3,LRRN3,KANSL1,PPP5C,PRKACB,PRKCB,MAPK3,MAPK9,SAMD9,SIDT1,PSMD13,BDNF-AS,ELOVL2,PTPRN,PTPRO,C1orf109,PEX5,TUG1,STRC,TMEM255A,RAP1GAP,RASGRF1,ARID4A,RGS7,NUDT11,ROBO2,ARMH4,ZC3H14,GLDN,TCP11L1,MAP6D1,ABCA11P,ZNF568,FAM182A,MIR124-2HG,ATXN1,HOGA1,TRIM46,GALNT10,MRAS,TRA2B,SCAF8,DOCK10,FBXO11,ST6GAL1,CCDC92,NUBPL,PAAF1,ABLIM3,FAM81A,DHX30,SLC6A11,ELMO2,LGI3,SMARCD3,ANKRD36,MBD5,FAIM2,SNRPN,UNC80,DOP1A,SOX5,ZSWIM8,IZUMO4,KIF1B,TSPYL2,DDN,SPART,PBLD,TROVE2,POGZ,ITPRID2,ZNF302,LARP4,INKA2,CEP68,STXBP1,AJAP1,FGD4,ASTN2,C12orf76,TACR1,ANKRD12,KAZN,CAMTA1,FAM208A,UNC5D,ADGRL3,KIAA1107,FBXW11,ANO4,ZFP90,ZEB1,SLC19A3,TNS2,RNF216P1,FAM200B,DNAH7,ITGB3BP,TIAM1,HEY1,TJP1,ZFP91,C5orf64,TPD52L2,TPM1,CDK20,NPL,ZNF346,AMACR,TRPC3,NTSR2,FLRT2,PLEKHH2,USP1,WIPF1,SLC13A3,XRCC4,PCDH20,TRIM9,ZNF70,ZBTB16,AMZ1,ANKS1B,UPF3A,CA10,EMSY,EVI5,STOX2,CIAPIN1,SEMA3B,NAV3,URM1,FAM47E,WIPF2,MVB12B,C12orf4,CASC15,CAMK1G,ZNF248,CBLN2,JPH3" MicroRNA hsa-miR-653:mirSVR_highEffct hsa-miR-653:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.51E-142 1.97E-138 6.26E-141 5.77E-140 361 1494 "ARID1A,KLRC4,SLITRK1,ADCY6,TMCC3,ADD3,BRAP,ERMN,PTCHD1,BEND6,INTS2,CC2D2A,LRRC7,MARCH4,PCDH10,FAM135A,CDC42BPA,PHF12,APC,UPRT,DDO,LGR5,MIER1,ARHGAP5,LINC00173,CDK13,ASPH,ZNF582,B3GALT2,N4BP2L1,DPY19L3,LINC00847,MPDZ,DCAF5,JAZF1,CACNB4,CALB1,CALB2,CAMK2B,CARS,MAP7,LDB2,KRIT1,AIFM1,SCARB1,TMEM257,CD38,CDH2,CLGN,CHM,CASC2,JAM2,CLU,C4orf33,HECTD1,FHL5,ARHGEF6,FAM149A,ABI3BP,TCEAL2,BAG4,ZFP28,CP,SLC35F1,CLOCK,CSF2RA,ATRNL1,SIPA1L1,SOCS5,PDE4DIP,FAM169A,CTNND2,RIMS2,USP6NL,CYBB,BOC,HDAC9,ZFYVE16,LIN54,PABPC5,C8orf34,ZBTB24,PLEKHM1,HEPH,KIAA0319,RHOBTB1,PLPPR4,SPOCK3,DLG2,DMD,HS3ST2,NR1D2,CDON,SLC25A18,EBF1,EDN1,FAM135B,EDNRA,EDNRB,HIPK3,GPR61,MBNL2,AASS,GOLGA7,RGS17,RCAN2,EPHA5,EPHB1,KCNMB2,SRRM1,EPS8,DENND4A,EFS,VPS26C,RRAGB,ADGRV1,CLVS1,FAM198B,WAC,TAOK3,FCGR1A,FCGR1B,ZSCAN30,GORAB,SEC24B,SUCO,HPCAL4,IP6K2,FLT1,SGIP1,SMC2,STAMBP,CELF1,DACH2,STAU2,SARAF,FYN,PHYHIPL,GABRA2,CAB39,GATM,IGSF5,GGTA1P,GHR,LYVE1,RUNDC3A,GK,SPIN1,TOX3,PCDH11X,MAP7D2,LUZP2,GNAL,LOXL3,GPM6A,LILRA1,GRIA1,DIDO1,GRIK2,CIT,TMEM25,MFSD2A,SOX21,GYG1,CELF3,IRAK3,PADI2,ELOVL5,SYNPO,HMGCR,HNMT,HNRNPK,DHX35,SHISA6,ZIC5,RBPJ,DOCK7,LIX1,DIPK1A,OLFM3,KCNJ10,KCNMA1,IPO5,LMO2,MAP2,MAP4,LYPLAL1,MBNL1,MOBP,MOG,ZNF680,MRPL42,MSRA,THYN1,SCG3,MTTP,RSPO2,MYO9A,ZNF862,NCAM1,NCAM2,NDUFA5,RCOR2,NELL1,NEUROD1,NF1,NFIA,NFYA,NOVA1,HCN1,CHAMP1,OPA1,OXTR,CNTN3,PBX1,PCSK5,PDE1A,GNG2,A2ML1,SNX10,KCTD15,GPSM2,PLCL1,JAKMIP1,PLIN1,PCDH18,HMGCLL1,LRP12,SCHIP1,ING3,SLC36A4,NXPH1,POU3F2,PPM1B,PPP2R2B,PPP3CC,KANSL1,PRKCB,GRAMD1C,HYDIN,PROX1,DCHS2,MASP1,CNNM2,VPS13C,SIDT1,MDGA2,PIGG,BDNF-AS,ELOVL2,TMEM260,STK32A,PTPRB,OCIAD1,PTPRD,PTPRG,PTPRO,PTPRZ1,QDPR,USP47,RAD17,FAT4,SUSD4,ZCWPW1,SLC6A15,ZYG11B,RFX3,RNASE1,ZNF532,RERGL,SETD5,CARF,ROBO2,NEK11,ATP8B4,PRR5L,ADAL,ABCA11P,CLIP1,SALL1,MIR124-2HG,SCN2A,SCN3A,SCN8A,NLGN4Y,ITSN1,CPEB3,MAGI3,CHD9,ANKRD6,ZNF365,PPP4R3A,RUFY2,CCDC88A,SLC12A2,ZNF334,SLC20A2,ATF7IP,SLCO1A2,TET1,SORCS3,SMARCE1,RCOR3,ANKRD36,SNRPN,UNC80,SOX5,TSPYL2,LMO3,TAB2,ATP10B,SSTR1,SS18,ELOVL4,TTBK2,FGD4,SYNE2,POPDC3,ANO4,TCF7L2,RPGRIP1L,WASHC4,WDR7,SYNE1,RALYL,SIRT1,ZFPM2,ITGB3BP,AP4E1,TIAM1,BHLHB9,ERCC6L2,FAM124A,ANKRD20A2,CLHC1,UBTF,WIPF1,ZNF781,ZBTB14,ZNF711,AGMO,LYPD6,ZNF138,WNK1,SLC30A4,EMSY,MFF,CADM2,PRDM10,HPS4,PARP11,RTN4,UBE3B,SMIM8,PHTF2,CASC15,ADAMTSL3,JMJD1C,NHSL1,SLC39A12,NETO1" MicroRNA hsa-miR-4254:mirSVR_lowEffct hsa-miR-4254:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.72E-142 2.09E-138 6.61E-141 6.09E-140 415 1959 "CPNE2,SYN3,ACADM,NBAT1,KLHL32,ADCY2,ADD1,SLC12A5,ADORA1,ADORA2A,KIAA1211,ESYT2,MTUS1,GPR158,RTL9,C1QTNF1,LRRC7,SPOP,ARHGAP20,BBOX1,ANK1,ANK2,FGD2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DGKZ,VAT1L,PPFIA3,AQP6,CDK10,SEMA4G,MADD,ARHGDIA,CDK13,ALDH4A1,ZNF583,SLC2A11,NOL4,TTLL9,ADGRB1,ADGRB2,BCL2L2,NAE1,LINC00906,SCAPER,CASTOR3,AP1M1,CACNB2,CALB1,NGB,VXN,MAP7,RUNX1T1,CLDN10,KYAT1,USP2,P2RX6,CD86,SYNGR3,ENTPD6,C1orf52,CDC25B,ARHGAP33,LRRFIP1,CCPG1,CACNA2D2,CHI3L2,CHM,SYNPR,TAOK2,NRXN3,DGCR9,CLTB,TMEM59L,FADS2,CNR1,PCYT1B,ARMC8,FAM149A,WHRN,CABP1,AHCTF1,SMARCAL1,MFSD4A,CHD1L,SLC35F1,CPS1,CLOCK,RNF14,SLC32A1,ANKRD44,CLIP3,CS,CSF1,CSF1R,SEC24C,LRIG1,OSBPL3,CSNK1G3,SUSD5,IPCEF1,PDE4DIP,CMTM5,PUM1,GPSM1,NOS1AP,RIPOR2,ARHGAP24,RASSF2,PHYHIP,DAPK1,DCC,ZEB2,B3GAT3,RUSC2,MED24,BLOC1S6,DDX46,POM121,TMCC2,ZNF582-AS1,GRIN3A,DNM1,HS3ST4,DNAH9,DOCK2,DMTF1,FAM57B,DRP2,GNE,DTNA,ABCC5,ABCC9,E2F5,WDPCP,ANKRD46,HIPK3,TMTC1,CELSR3,FAM13A,APH1A,EGFR,ABI2,RASA4,ELN,EPB41L1,GPHN,NCALD,MRPL37,APC2,TMEM74,RASL12,EXTL1,SIRPB1,EXTL2,CLVS1,ZIC4,PPP1R1B,ZNF589,OLFM1,FGF11,FGF13,HPCAL4,FOXG1,SYNCRIP,ZBED3,TRIM16,ZNF605,MPP6,DKK3,GABRB1,GALNT15,GABRG2,AHCYL1,BRPF3,SRRM4,WASF3,LRRC37A6P,ALDH1L1,SRCAP,CYP46A1,GFER,USP19,TTBK1,CRCP,GLI2,TOX3,ZNF638,RAB40B,GNAO1,GPD1,RAPGEF1,GRIA4,SPACA9,ADAMTS13,GRM1,GRM7,LINC00839,AP4S1,LINGO1,RNFT2,GUCY1B1,MAP4K5,HAS2,VSIG4,AGBL5,OPALIN,AGFG1,HSD17B1,HSF2,CELF5,SMAP1,HTR5A,FAM95B1,RBPJ,TJAP1,IL6ST,IL11RA,KCNA1,GPR62,A1BG-AS1,STXBP5,LAMA2,SYTL4,VWA5A,ARHGAP12,MAN2A2,MBNL1,SCAMP5,MID1,PPM1L,XRRA1,WDR49,SAMD5,MSI1,PTOV1,C10orf105,MYH6,FXYD7,NBL1,SFR1,RCOR2,NELL1,NEK1,NHLH1,NINJ2,NTRK3,NUCB2,SNTG1,PCSK5,PDE2A,PDE4A,PIRT,GNG2,BEST3,NALCN,SEMA5B,FAM218A,TMEM38A,PKM,FTO,SMOX,PCDH18,LRP12,SCHIP1,PRRX1,TNPO2,PPP2R5C,PPP3CB,PRKCB,PRKCZ,MASP1,WBP1L,SIDT1,PSMD13,PLPPR1,PTK2,DKFZp779M0652,FAM120C,C1orf109,NKAIN1,STRC,RAB3IL1,CEP97,PLEKHB2,FAM66C,RASGRF1,RET,REV3L,RFX5,RGS12,RIC8B,KLHDC8A,CYB561D1,RPE65,SNX22,NEK11,MCMBP,SGSM1,PRR5L,ACER3,MEG3,ABCA11P,KCNIP1,MAPK12,SEMA6D,LRFN5,FAM19A1,TNFRSF19,SEC14L1,TRIM46,GALNT10,SFPQ,KIF27,FAM102A,FERMT1,HKDC1,MAGI3,AMBRA1,SLA,WDR47,KANSL3,SLC8A2,SLC8A1,SLC8A3,SLC12A2,SLC15A2,TMEM132D,NAXD,MAST1,SORCS3,SMARCD3,MYH15,IFT122,LIMCH1,MBD5,CMTR2,SNRPN,DOP1A,SOX5,KIF21B,SOX10,SP4,TEX2,CDK19,TSPYL2,LHPP,TAB2,CLSTN2,COLGALT2,STOX1,SSTR1,NXT2,NEK4,GANAB,ACSBG1,FGD4,SYP,TACR1,MTCL1,EXOC7,ALG1,ADGRL3,ANO4,SIN3B,SATB2,TRIM2,OBSL1,NSD1,DICER1-AS1,TIAM1,DDHD1,DAAM2,CSMD1,PIK3R5,RASD2,NPL,WBP2,TRO,TUB,ZKSCAN5,VAV1,WIPF1,KLC2,SF1,ZNF74,PLPP4,NDRG4,TCEAL7,ZBTB38,TMEM237,FSTL5,TMEM198,SLC30A4,PMEPA1,CSDE1,LMAN2L,HPS4,SEMA3B,GAL3ST3,SLC17A7,FIP1L1,CAB39L,TRIM16L,WIPF2,UBE3B,KAT6A,CASC15,TRAM2-AS1,FRMD6,NETO1,CBLN2,ST8SIA2,SLC4A10,FAM198A" MicroRNA hsa-miR-618:mirSVR_lowEffct hsa-miR-618:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.91E-142 2.20E-138 6.93E-141 6.39E-140 373 1594 "SDE2,ABAT,NCKAP5,SYS1,ADAR,GALNT16,GALNT13,RNF157,ADD2,PLEKHH1,PWWP2A,RNF150,AP2A2,TAOK1,ALAD,BCAR3,MARCH4,UNC79,ZFAT,CDC42BPA,LRCH2,EP400,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DDO,VAT1L,SHTN1,TMEM263,LINC00173,MARK4,ASPH,ZSCAN18,CHRD,EIF4G3,ATP1B3,STX16,RNF182,RIPK1,DOCK11,BACH1,BARD1,BCL7A,SCAPER,MTMR3,MTMR2,CA8,CACNA1E,KALRN,PTBP2,CAMK2D,SYT6,NFS1,CCNH,REPS2,CDC27,CDC42,CDH8,LGI1,CCPG1,CFL2,CHM,NRXN3,NMT2,TMEM59L,QKI,MAP4K4,NIPBL,AKAP7,IQCK,AKAP6,COL11A2,AKAP5,RCHY1,CHD1L,PNKD,CLOCK,PREPL,CREM,HAPLN1,SLC32A1,SNCAIP,ARHGEF10,SOCS5,CST3,APPL1,UBXN2A,PHF14,GREB1,RIMS2,ST18,CX3CR1,ECE2,CCDC144A,NOS1AP,BOC,GAPVD1,ARHGAP24,DGKB,DAPK1,SIRPA,DNAL1,HP1BP3,COPS7A,C2CD2L,POM121,SV2B,WDR20,DLG2,GRIN3A,RPS6KL1,DNM1L,EDN1,TMTC1,SH3GLB1,PHF20L1,ABI2,IRAK4,TNK2,PCOLCE2,ECSIT,F3,SH3YL1,SCML2,FCGRT,ZNF589,MED12L,OLFM1,AMOTL2,SCARA3,MEX3B,HPCAL4,CAP2,FLT1,UFM1,TRIM16,CAMKK2,DACH2,MEGF10,GABRA2,CAB39,GAD1,ERAP1,TMEM8B,MTHFD2,LRRC37A6P,MYOZ2,SULT1C4,CYP46A1,ADAM28,PCDH17,PPARGC1A,MALT1,TOX3,ZNF638,KDM2B,LUZP2,KCNMB4,DCLK2,ATF7,TMEM121B,RAPGEF4,GRIA2,GRID1,GRIN2C,NR3C1,KIF3A,GUCY1B1,CELF3,RASSF8,PADI2,ZHX1,FRMD3,ARHGAP36,ELOVL5,GABARAPL2,HTR5A,MSL1,SCIN,IL6ST,INPP5B,INSM1,LRRTM1,NME9,OLFM3,CDH20,KCNJ10,KCNJ16,KTN1,LAMP2,FGFBP3,C2orf80,MBD1,SYT9,IL17D,LDLRAD3,TM6SF1,MEIS2,MID1,XRRA1,SAMD5,MSR1,MTR,HS6ST3,NACA,TCEAL5,NDUFA5,NFIX,SLC11A2,GPR88,PCSK1,PCSK2,PDE4D,PIRT,CDK14,DUSP26,ANLN,ZNF655,PLP1,PACSIN1,TNPO2,POU3F2,PPP2R5C,EPDR1,MAPK9,DIRAS2,VPS13C,SNRK,PTCH1,TMEM260,STK32A,PTPRG,FAM120C,PTPRZ1,RIPOR1,ZSCAN2,TUG1,STRC,TMEM255A,USP47,FAM66C,ENOX1,ZNF493,ARID4A,RBBP8,GTDC1,RFX3,PRIMA1,ARHGEF10L,CCDC82,ROBO2,YY1AP1,CCDC102B,ARMH4,GLDN,PRR5L,ADAL,LRRK2,CNTNAP3,NCBP3,ZNF331,TRAPPC13,SATB1,CSRNP3,ATXN7,SOX6,TRA2B,NLGN4Y,FRMPD1,MAGI3,CHD9,DZIP1,ZNF365,SLC1A7,PREX2,RUFY2,LRRC55,KDM4D,RAB3GAP1,SLCO1A2,TET1,EPC1,RCOR3,IFT122,ANKRD36,LIMCH1,CABCOCO1,LMBRD1,SNRPN,TMCC1,UNC80,MYT1L,NMNAT2,EMC1,TSPYL2,NFASC,SRPK2,ATP10B,FGD4,ABCC8,VAMP1,ADAMTS17,COBL,ANKRD28,TAC3,TACR1,ANKRD12,KAZN,MTCL1,MCF2L,PDLIM2,UNC5D,ADGRL3,TMEM136,KLHL4,CUX2,ZEB1,RPGRIP1L,TCF12,WASHC4,WDR7,AZIN2,PHF24,PUM2,USP32P1,TNS2,FRYL,FAM200B,DICER1,ZFPM2,TGFBR3,GALNT17,ZFP91,R3HDM1,CSMD1,KAT6B,TNR,TPD52,RGMB,TRO,STXBP4,TSC1,CLEC2L,FLRT2,ZNF709,RICTOR,CFAP298,ZNF24,FMN2,MKRN3,ZNF154,EML6,ZSCAN26,ANKS1B,SPIRE1,SYNC,UPF3A,WNK1,EVI5,ADAMTS9,PPP1R3F,FAM47E,MVB12B,EPM2A,RGS7BP,DNAH10,FAM13C,SMIM8,PHTF2,ADAMTSL3,SSPN,FRMD6,FAM198A" MicroRNA hsa-miR-653:mirSVR_lowEffct hsa-miR-653:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-142 2.74E-138 8.63E-141 7.95E-140 406 1880 "SERPINA3,ACADM,NCKAP5,XKR4,CSMD3,NDRG3,CCDC85A,KLHL13,CASKIN1,PCDH19,HACE1,OSBPL6,AK2,SPARCL1,ALCAM,BCAR3,GPRASP2,SYT13,BEGAIN,TRMT9B,AMPH,CCDC146,ANXA7,APBB2,LRRC4C,USP37,SHTN1,SLC7A14,PPP4R4,RGS20,BRINP2,ZBTB10,CCAR2,TMEM108,SLC4A4,ATP1B3,ATP2B1,ATP2B2,ATP2B3,ADAM23,ADGRB1,ADGRB3,KSR1,CDK5R1,LDLRAD4,CACNB2,KALRN,PTBP2,CAMK2D,TRIM41,RUNX1T1,PRC1,CBR1,ENTPD6,C1orf52,CDH8,DCLK1,B4GALT6,KMT2C,NRXN3,CLTC,FAM19A5,QKI,NIPBL,CNN3,CNTN1,AKAP6,WHRN,AKAP5,RCHY1,SMARCAL1,RTTN,MYRIP,HS3ST5,FAM171B,CDC42BPB,SH2B1,CREB5,ANKRD44,NCOR2,GDA,MICAL2,CSNK1E,CSNK1G3,IPCEF1,SIPA1L1,UBXN2A,PHF14,PUM1,ST18,ZSCAN23,SEC14L5,ARHGAP24,ZNF337,MATR3,KIAA0586,DGKB,DGKG,TMEM170A,TOMM20,DBI,GIT2,DNAL1,ARMCX4,DCC,ARMCX2,ZEB2,KLHL3,DDX46,POM121,SACS,MTX3,OLIG1,USP3,DMTF1,GNE,DTNA,DNM1L,GOLT1B,E2F5,SGK2,TMTC1,SH3GLB1,KMT5B,TENM1,ELAVL4,OLIG2,EPB41,GPHN,ERBB4,DNAJC27,RCSD1,EZH1,NRN1,F5,RPS6KC1,TBC1D16,ATP8A1,TOMM40L,TESK2,SPSB4,FGF13,SCARA3,CAP2,FOXF2,AGAP2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,NELFCD,UFM1,ST6GALNAC3,CSPG5,AP4B1,NRG3,STAG2,CHL1,GABRG1,GAD2,HBS1L,ZMYND11,JPH4,ARPP21,NCKAP1,GAP43,WASF3,GCNT2,TUBGCP4,MSTN,ARFIP1,CYP46A1,MALT1,COPS8,RAB30,GLS,TNRC6A,ZNF638,KCNMB4,RAB40B,NUDT21,PCLO,RAPGEF4,STMN2,SERP2,FAM19A2,COQ10A,KAT7,RABL2A,LINGO1,RNFT2,GUCY1B1,MAP4K5,WIF1,MAEL,RASSF8,HAS2,MAN1B1,INSYN1,HMGB1,AGBL5,HSF2,EID2B,PLD5,IGSF1,SCIN,IL6R,INPP1,INPP5B,INSM1,ZNF385B,KCNJ3,KCNK2,KCNN2,KTN1,INSYN2,SYTL4,HECTD2,C2orf80,GPR155,NAT8L,MAT2A,CHIC1,MDM4,MEIS2,PPM1L,AFDN,XRRA1,ADAM22,TAGLN3,CTNNA3,MYO6,MYO7A,NAP1L1,NAP1L2,ZC3H12B,NTRK2,NUCB2,IGSF11,SNTG1,PAK3,PAX6,PC,PCDH9,PDE3B,PDE4D,SLC10A4,OLA1,CAMKV,PIK3C2A,PIK3R1,ZNF655,ST8SIA5,PRIMPOL,MAGEL2,EPB41L4B,DRAM2,RASGEF1B,SLC22A23,GON4L,PSMD13,ANKHD1,MTMR10,PTN,PTPRE,TTC13,ZNF615,PLEKHB2,ARID4A,RDX,GAL3ST4,ERI2,GTDC1,FIGN,RGS3,RGS10,RIC8B,RPRD1A,ZFHX4,GSTCD,ARMH4,UEVLD,BAALC,WLS,SATB1,ATXN1,LRFN5,SCP2,SEC14L1,SCG5,FERMT1,NTNG1,HKDC1,FNDC3A,ST3GAL3,DZIP1,ABLIM3,SLC1A3,WDR47,SLC6A8,ZNF430,SEPHS1,SLC8A1,RAB3GAP1,BTBD7,CPEB4,GKAP1,SMARCA4,TTC17,MYO16,KDM4B,FAM219A,DOP1A,SON,TRERF1,SOX2,KIF21B,BDP1,SP4,NMNAT2,GLT8D1,KDM4C,PEG10,KIF1B,ZBTB43,NFASC,ZNF621,CLSTN2,POGZ,ITPRID2,ZNF302,LARP4,CEP68,SEPT3,NECAB1,DNAJC9,C3orf70,SYT1,TAC1,TAC3,TACC1,PJA1,MCF2L,FAM208A,UNC5D,WWC1,TMEM136,EHBP1,VWC2,TCF4,DMXL2,SATB2,ZFP90,DOCK9,GPRIN3,AHCYL2,CRB1,HHIP,AKTIP,SLC44A1,TLL2,RIMBP2,TPD52,TPM1,NPL,TRIO,AMACR,ANO5,TMEFF2,UBC,EIF4ENIF1,AMOT,UCHL1,GORASP1,SLAIN1,FLRT2,USP1,TBC1D15,NSD2,WNT7A,CLDND1,GUSBP1,SF1,ZIC1,ZNF708,KCNT2,ZNF540,ANKS1B,SPIRE1,PLPPR5,UPF3A,INTS3,CA10,XKR7,NAV2,FIP1L1,FAM47E,SLC17A6,RGS7BP,FAM13C,AMN1,KAT6A,HNRNPA3,CERS6,NLRP3,MSRB3" MicroRNA hsa-miR-182-5p:TargetScan hsa-miR-182-5p TargetScan 5.02E-142 2.82E-138 8.85E-141 8.15E-140 291 963 "AS3MT,ADCY2,ADCY6,ADD3,GRAMD1B,KIAA1211,PTCHD1,GPR158,HECW2,KLHL13,KCTD16,KIAA1324,LRRC7,ABCD2,PCDH10,GPRASP2,PDZD4,OGT,CDC42BPA,LRCH2,ANK3,PHF12,APBA2,ARHGDIA,MARCH3,NUMB,ASTN1,ATP1B3,DPY19L3,DOCK11,BMPR1B,DST,JAZF1,NIPA1,CACNA1B,CACNA2D1,CACNB4,PRC1,REPS2,CDC27,EVI5L,LGI1,MAGI1,DLGAP2,CACNA2D2,FOXN3,RAB3C,NMT2,QKI,NIPBL,CNGA3,CNN3,CNR1,CNTN1,RTTN,BAG4,MYRIP,IGDCC3,CLOCK,PREPL,C2CD2,ANKRD44,AATK,APPL1,NRSN1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,KIAA0513,KIF26A,RIMS3,KIAA0087,GIT2,DNAL1,JAKMIP2,PLEKHM1,ELMO1,RHOBTB1,AK5,KIF19,CALN1,DYNC1I1,DSCAM,GNE,DYRK1A,EBF1,EDNRB,FEM1B,FAM13A,PHF20L1,MBNL2,EGR3,EIF5,ELAVL2,ELAVL4,RGS17,C8orf37,PAN3,EPHB1,KCNMB2,GPHN,RAB9B,ERBB4,NCALD,CEP85L,NRN1,ATP8A1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,NSG2,CELF1,NSG1,FUT9,PHYHIPL,GABBR1,CHL1,GABRB1,GAD2,AHCYL1,BRPF3,B4GALNT1,RAPGEF6,NCKAP1,ATP8A2,GK,KDM2B,PRUNE2,GPR22,NUDT21,RAPGEF4,GRIA1,GRID1,GRIK3,GRIK4,GRM5,KAT7,GUCY1A2,FAM107A,ATOH8,HAS2,FRMD5,BACH2,C2orf72,KCNA2,CDH20,KCNJ5,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,PIK3AP1,NAT8L,CHIC1,LRP1B,MEF2C,MEIS2,PPM1L,MITF,MMP16,ADAM22,MYO9A,PABPC1L2A,NAP1L1,NF1,NKX2-2,NOVA2,NPTX1,NPTX2,NRCAM,OCRL,CHAMP1,OGDH,OPHN1,KCNK10,PAX6,PC,PCDH8,PCMT1,PCSK5,CDK18,PDE4D,PIRT,PDGFRA,GPR173,GPR85,ANLN,PIK3R1,FAM216A,PLCL1,PCDH18,HMGCLL1,LRP12,PRRX1,MAGEL2,EPB41L4B,FAT3,MED1,PPP3CA,PRKACB,CEP41,PKN2,CNNM2,EML5,PTPRG,PTPRN2,MARCH1,RALGDS,ATG16L1,ARID4A,RDX,FIGN,ALG9,RAVER2,FBXW7,MCMBP,ACER3,RIMKLA,FOXRED2,CSRNP3,ATXN1,ATXN7,SCN2A,SCN3A,SCN8A,MRAS,PPP1R9A,NTNG1,CCDC92,RPH3A,CCDC88A,ATF7IP,LIMCH1,PALLD,FAM126B,PDZD2,MYT1L,FNBP1,ERC1,PEG10,IQSEC2,NFASC,CLSTN2,LRRC4,NXT2,PHLDB1,FAM168A,KLHL7,FGD4,CAMSAP2,FBXW11,SATB2,DOCK9,NSD1,ARHGEF12,CRTC1,GPRIN3,DICER1,HHIP,ASXL3,DDHD1,RIMBP2,KCTD2,RUNDC3B,PPIL6,DCBLD1,CADM1,BCL2L13,RICTOR,REEP1,CA10,CADM2,EVI5,CIAPIN1,RGS7BP,AMN1,FZD3,RTN4,CERS6,JMJD1C,FXR1,GAN" MicroRNA hsa-miR-671-5p:mirSVR_lowEffct hsa-miR-671-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-142 2.97E-138 9.29E-141 8.55E-140 381 1663 "CPNE2,RALGAPA1,TTYH1,SYS1,ACTN1,CSMD2,ADCY6,ADD1,ADD2,SORCS1,ERMN,KIDINS220,AP2A2,AP1B1,KLHL13,PCDH19,HACE1,SYT13,PDZD4,ANK1,EP400,PI16,USP28,PPFIA4,PPFIA1,DGKZ,PHYHD1,AQP6,PDXK,CASK,CADPS,ASCL1,NUMB,ATP1A2,SLC4A4,RIPK1,ADAM15,SNAI3-AS1,BARD1,MPDZ,IL33,CA4,CACNB2,CACNG1,CABP7,KALRN,HAP1,CAMK2G,PRC1,SCARB1,SYNGR3,DGKI,ARHGEF2,LGI1,NOG,B4GALT6,CNOT8,JAM2,CPNE6,DNAJB5,HECTD1,FAM149A,SLC4A8,ZNF385A,CRMP1,ANKRD44,ABCG1,CS,SNCAIP,CSF2RA,CSF3R,ARHGEF10,CSNK1G3,SIPA1L1,KIAA0040,CTNND1,EDRF1,HDAC9,KIAA0513,ZNF337,IST1,IP6K1,ELMSAN1,ZEB2,ZBTB24,MFAP3L,RUSC2,MED24,KLHL3,GSDME,RHOBTB1,SNAP91,SV2B,NTM,RABGAP1L,DLG2,EXOG,SLC29A4,DNM2,DOCK2,FAM57B,ABI1,DTNA,ECM2,AASDH,SNX29,EDN3,ATL1,SYT15,KLHL5,CACNG7,EFNB3,CELSR3,EBI3,C3orf18,EMX2,VPS13B,EPB41L2,SEZ6,GPHN,ANKRD13B,STX2,RTN3,F5,CLVS1,TOMM40L,FCGRT,KAT8,FGF13,TMEM164,FHL1,MEX3B,HPCAL4,IQCG,FOXM1,FOXO3,SYT3,EFCAB2,ZCCHC17,CAMKK2,ERGIC3,KHDRBS3,CGREF1,B3GAT1,TMEM151A,OGA,GABRA2,BRPF3,ZMYND11,GHDC,HIGD1B,TMEM8B,C15orf41,INPP5K,GATM,TUBA8,CYP46A1,GFAP,ADAM28,GGT7,GNG3,WDFY3-AS2,PRRC2B,GPD1,GPD2,TDRKH,STON1,GRIA1,GRIA2,GRIA4,PLCD4,ADAMTS13,GSTM5,FAM107A,SLC2A6,ATOH8,IGSF21,HRH3,ZDHHC15,LRRC75A,CELF5,SMAP1,NKD1,KIAA1755,LIX1,SCRT2,ZNF678,ZNF385B,ITGA7,ITGAM,C2CD4C,SLC35G1,KCNA6,KCND1,KCNQ3,KHK,KIF5A,LINC00634,LAMP2,STMN1,ZFYVE27,CHST6,DBNL,SAMD5,MXI1,LYRM9,MYH6,MYO7A,MYO9A,NACA,FXYD6,NFIA,NFYA,DNHD1,NTRK2,NTRK3,NUCB1,TBC1D25,IGSF11,LOC100128398,ZDHHC22,PDE4D,ZNF655,A2ML1,PLCB2,SLC25A23,C11orf49,MAPKAP1,CDIP1,SEPT4,MBOAT7,SH3KBP1,PTPA,PPP3CA,MAPK10,DIRAS2,BCAS3,GON4L,PIGG,UHRF1BP1,ELOVL2,PXK,TMEM260,ZSCAN32,OCIAD1,PTPRE,FAM120C,PLEKHB2,RASGRF1,RASGRF2,VEPH1,RDX,FIGN,RFX4,RGS3,RGS7,EXD2,CARF,ROBO1,MRAP2,SNX22,NEK11,FBXW7,BAALC,GLDN,PRR5L,ADAL,ACER3,STK32B,MAP6D1,EMID1,HSD11B1L,SCN4B,CASC3,SFPQ,ITSN1,SH3GL3,FRMPD1,ST3GAL3,ABLIM3,SLA,URGCP,SLC2A5,SLC6A8,SLC8A2,SLC9A5,TRIM67,SLC11A1,SCMH1,ELMO2,SLC20A2,SMARCC2,MYH15,SMARCE1,RCOR3,ANKRD36,SNCB,SNRPN,UNC80,KDM4B,USP33,FAM219A,WDTC1,ZSWIM8,EMC1,PEG10,BEX1,KIF1B,NFASC,CLASP2,SMOC1,SSTR2,EPB41L3,INKA2,SEPT8,ADHFE1,SYNE2,ARHGEF9,SYN1,SYPL1,TACR1,ROBO3,CAMTA1,MLST8,EXOC7,TBCEL,IQCE,SMG6,ANO4,TBX15,VWA3A,NEU4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,AP4E1,TMEM9,TLR4,DAAM2,TNFRSF1B,KAT6B,NPL,WBP2,AMACR,TRPM2,ZMYND8,FNDC5,TSN,LINC00689,MEAF6,RBFOX3,GUSBP1,SLC47A2,ZNF708,TRIM9,NDRG4,SLC26A10,LYPD6,AMZ1,EML6,DPYSL5,SPIRE1,DHX33,WNK1,PRTFDC1,FIP1L1,LINC00632,PCBP4,WIPF2,PDSS2,RGS7BP,RTN4,UBE3B,FBXO36,FAM219B,JPH3" MicroRNA hsa-miR-628-5p:mirSVR_lowEffct hsa-miR-628-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.26E-142 4.08E-138 1.27E-140 1.17E-139 378 1639 "RALGAPA1,KCNH8,ABR,ACADM,NCKAP5,NBAT1,SYS1,ARID1A,CSMD3,TMEM132B,DSCAML1,ADCY6,RNF150,KIDINS220,BEND6,NLGN4X,SNX32,KIAA1324,SMIM17,ALCAM,ARHGAP20,ZFAT,EP400,PPFIA1,MAGEE2,DGKZ,API5,SHROOM2,AQP4,AQP6,CDC14B,PDXK,CDK13,ASPH,ASTN1,ATM,ATP1A2,SLC2A11,DCAF5,NRP2,CDK5R1,DST,FUBP1,LINC00906,CA8,CACNB4,DIRAS1,TRIM41,HIP1R,METTL6,MTMR7,AIFM1,CBFA2T2,SCARB1,ENTPD6,CDC42,DCLK1,LOC730101,LARGE1,TIGD7,NOG,SOCS6,CHM,SYNPR,LSMEM2,CNN3,AKAP7,ARMC8,SLC4A7,SLC4A8,RTTN,MYRIP,ZFP28,SLC35F1,CRY2,TRIM69,CS,SNCAIP,FEZ2,MICAL2,SUSD5,ATRNL1,PDE4DIP,PLXNA4,DZIP3,CFAP61,CTNND2,NRSN1,RUBCN,CYBB,ARHGAP32,FGFR1OP2,HDAC4,DGKB,SCRN1,AIF1L,JAKMIP2,ZEB2,PLEKHM1,ELMO1,SV2B,SRGAP3,AK5,G3BP2,RABGAP1L,WDR20,DLG2,NYAP1,USP3,DPH1,SLC25A18,PDCD6IP,DTNA,DYRK1A,E2F5,E2F6,FAM135B,EDNRB,PHC2,TMTC1,FAM13A,IRAK4,BSCL2,ENO2,ANKRD13B,SRRM1,ZNF549,SPEG,MRPL37,ANKMY1,RASL12,RRAGB,HSPA12B,WAC,CORO2B,EFEMP1,ATP8A1,CEP78,FKTN,GTF2IRD2,POLK,CAP2,FLNC,NELFCD,TMEM107,SMC2,STAMBP,KHDRBS3,DACH2,STAU2,KBTBD12,MEGF10,GABRA2,HBS1L,ZMYND11,SALL3,SIGLEC8,C15orf41,DISC1,ATP8A2,INPP5K,TUBGCP4,MMADHC,FREM1,GGT7,PPARGC1A,LYVE1,GNAS,LNX1,GPM6A,ATF7,LILRA2,GRIA1,GRIA2,GRID1,GRIK2,GRIK3,NR3C1,GRM1,GRM3,FAM19A2,ZBTB49,RABL2A,FAM107A,GUCY1B1,FRMD3,MIER3,HMGCR,ZDHHC15,SHISA6,IRF8,USP54,SCIN,IL6R,ZNF678,KCNC2,CLVS2,KCNK2,CREG2,KIF5A,CYP27C1,SFXN5,PAXBP1,PACRG,SYT9,CHIC1,MEF2C,AFDN,COL28A1,SAMD5,NRBP2,MYH6,MYO5A,MYO6,ZNF862,PABPC1L2A,HNRNPM,FXYD6,P2RY13,NEK1,NME4,NOS1,DNHD1,SLC11A2,NTRK2,NTRK3,OPCML,OPHN1,SNTG1,CNTN3,PCDH8,PCMT1,PRTG,PDE1A,GNG2,PFKFB4,PFKP,HERC2P3,NALCN,PLCB2,FTO,HMGCLL1,PDZRN4,TRHDE,LRP12,PRRX1,TNPO2,MINDY2,CCDC144B,PPP2R5C,PPP5C,RASGEF1B,PRKACB,MAPK4,MAPK8,MASP1,CNTLN,PLPPR1,NCR3LG1,BDNF-AS,ZSCAN32,PTPRB,OCIAD1,PTPRE,PTPRG,PTPRZ1,ACSM5,ACSS3,CCDC40,RASGRF2,RBBP6,RET,ERI2,UBR7,RGS12,SEC61A2,RPRD1A,MYH14,TMLHE,KIRREL1,YY1AP1,ARMH4,ZNF671,GLDN,ADAL,PAQR6,HSD11B1L,KCNIP2,DGLUCY,SALL1,SCN2A,SCN8A,ASIC4,ELMOD1,GALNT10,ASRGL1,ITSN1,CPEB3,SHC4,AMBRA1,ST6GAL1,ANKRD6,RPH3A,PPP4R3A,SMTN,LRRC55,SCMH1,SLC20A2,SLN,IGSF9B,LIMCH1,SNRPN,SCN3B,ZCCHC24,KIF21B,TEX2,RAP1GAP2,SPART,ITPRID2,ELOVL4,CEP68,DIP2A,PHLDB1,FGD4,VPS13A,FAM208A,UNC5D,ADGRL3,TCF4,TPCN2,TRIM2,SYNE1,AHCYL2,SIK3,VWCE,FAM200B,LEFTY2,ZMAT3,AKTIP,SLC44A1,MTMR14,TJP1,TK2,ZFP91,NR2E1,TPM3,PPIL6,SSBP2,CLHC1,SGK3,FAM155A,WIPF1,ZNF711,ATP6V0E2,ZNF70,MKRN3,ZBTB16,TMEM237,FSTL5,SPIRE1,FTSJ1,PLPPR5,EMSY,STMN4,PRDM8,PRDM10,PCDH15,FIP1L1,MVB12B,PLSCR4,C12orf4,FZD3,UBE3B,HNRNPA3,NUP214,ZNF248,FRMD6,GAN" MicroRNA hsa-miR-595:mirSVR_lowEffct hsa-miR-595:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.90E-142 5.56E-138 1.73E-140 1.59E-139 394 1778 "ADCY2,SLITRK1,ADCY6,TMCC3,ADD2,CDC7,UNC5A,RNF150,SLC24A4,INTS2,CASKIN1,PCDH19,WDR35,OSBPL8,ARHGAP20,ALK,AMPD2,CDC42BPA,ANK1,LRCH2,PKP4,APAF1,APC,TNRC6C,MIER1,SEMA4G,TMEM263,ARHGAP5,CADPS,STK33,ASPH,TMEM108,EIF4G3,RNF182,NOL4,ATP6V1G2,ATP6V0A1,MYOM1,RIPK1,ADAM15,ADGRB2,ADGRB3,SEC11C,RGS9,BCS1L,LINC00906,SGCE,IL33,CA4,CACNA1E,CALB1,THSD7A,CALM1,PTBP2,CAMK2D,CH25H,CBR1,CCK,CD86,SEPT7,REPS2,CDC27,CDC42,CDH2,LRRFIP1,CHGA,CASC2,KMT2C,EPS15L1,CLTB,FAM19A5,HECTD1,NIPBL,FHL5,FAM149A,AKAP6,ABI3BP,ZNF521,HS3ST5,SLC35F1,CLOCK,CS,IPCEF1,KIAA0040,UBXN2A,CTH,CTNND2,ST18,FAM131B,KIAA0408,ZFYVE16,TOMM20,PABPC5,ARMCX4,SPATA2,YTHDC1,CEP170,SV2B,SPOCK3,SRGAP3,AK5,WDR20,DLG2,DNM2,DOCK2,DMTF1,DYRK1A,ABCC5,E2F5,EDN1,PHC2,PHF20L1,EGFR,MRO,ABI2,IRAK4,STARD3NL,DENND4A,VPS26C,TLR7,EXTL1,EZH1,F5,ARMCX1,CLVS1,ABCA8,WAC,TBC1D16,EFEMP1,TOMM40L,PPP1R1B,MED12L,CAP2,FLT1,EFCAB2,JKAMP,ATP6V1H,CELF1,CGREF1,MPP6,MEGF10,GAB1,HRASLS5,DENND2A,HBS1L,IQGAP2,CPLX2,ALDH1L1,SULT1C4,MSTN,ADAM28,MALT1,RNPS1,TOX3,GLUL,PCDH11X,ZNF638,RAB40B,GNAL,FERMT2,GPD2,CECR2,PCLO,GRIA1,GRIA2,GRIA4,GRIN2D,CIT,KIF3A,CLASRP,TMEM25,ZBTB49,PSIP1,WIF1,LINC01102,IDH3A,LINC00667,ZNF546,DOCK7,KIAA1755,SLC35G1,METTL21A,KCNB1,KCNC2,KCNJ9,KCNJ16,KCNK1,KIF5C,KIT,KLRC2,KTN1,PAXBP1,NCOA7,LSS,MAOB,MAP4,MARK1,MAT2A,MATN2,MATN3,CHIC1,MEF2C,MEIS1,MEIS2,MIA2,POC1B,AFF1,AFDN,XRRA1,ERICH3,CCDC80,BCO1,SCG3,CTNNA3,MTTP,HS6ST3,MXI1,NAP1L1,NF1,SLC11A2,NRCAM,NTRK3,DDR2,NUMA1,OXTR,P2RY1,TREM2,CDK18,ENPP2,FAM98B,PFKP,NALCN,PIK3C2A,PLCL1,PLP1,PLXNB1,PLXNB3,PURG,PRIMPOL,ANKRD16,PMP22,PSAT1,ING3,PPARA,TMEM235,PPP3CA,RASGEF1B,PKN2,MAPK4,MAPK9,HYDIN,DIRAS2,PRODH,PROX1,PRPSAP2,SAMD9,BCAS3,MDGA2,QRICH1,BDNF-AS,PTPRB,PTPRE,CASTOR1,FAM120C,NKAIN1,PPP2R3C,TMEM255A,FAT4,RAP1GAP,ZNF493,REV3L,RFX3,RFX4,RGS3,RGS4,ARHGEF10L,SEC61A2,PBRM1,ZFHX4,RNH1,EXD2,CCDC102B,RPL15,UEVLD,FAM161B,MEG3,CLIP1,RYR3,FAM192A,AP1AR,SEMA6D,ATXN1,ATXN2,HOGA1,SCN2A,PRCD,SCP2,NLGN4Y,PPM1E,FERMT1,MAGI3,FBXO11,DZIP1,URGCP,RUFY2,SEPHS1,SLC8A1,RAB3GAP1,SPHKAP,INTS9,DOP1A,PDZD2,WDTC1,MYT1L,BDP1,ENKUR,MYCBP2,KDM4C,IQSEC2,RBM26,NPAS3,NFASC,CLASP2,POGZ,COLGALT2,FCHO1,SEPT8,DIP2A,ADHFE1,KANK1,SEPT3,NSFL1C,FGD4,VAMP1,SYT1,KAZN,DDHD2,ALG1,IQCE,TMEM136,EHBP1,TCF4,TRIM2,PCDHGA11,DOCK9,TEX15,SIK3,DNAH7,CRB1,THRA,GZF1,ERCC6L2,TMOD1,FAM124A,PRRT1,C5orf64,TP53BP2,TPM1,SYNPO2,ZMYND8,PPIL6,FNDC5,ANKRD20A2,TTTY15,RFTN2,TTC3,OSBP2,FLRT2,PLEKHH2,LMF1,GUSBP1,XRCC4,ZNF708,ZNF540,TCEAL7,ZBTB16,EML6,ZFAND5,WNK1,CA10,EMSY,PRDM2,LRP8,SLC38A1,LINC02210,ADAMTS9,PDSS2,JMJD1C,RNF170,MSRB3,SNX14,PIANP,FRMD6,NETO1" MicroRNA hsa-miR-3157:mirSVR_lowEffct hsa-miR-3157:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-141 6.13E-138 1.90E-140 1.75E-139 407 1893 "SDE2,DGCR6,ABCF1,ACTN1,CSMD2,ADCY2,PSMG3-AS1,ADCY6,TMCC3,ADD2,SORCS1,ADORA2A,FAHD2CP,BEND6,AP2A1,PCDH19,CC2D2A,TAOK1,SPOP,FAM135A,AMPD2,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,PARG,GPAM,BCAS1,CDC14B,IGDCC4,SPTBN4,ARHGAP5,ZBTB10,TMEM108,ATP1A2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ADAM15,LINC00847,BBS2,DNAJC27-AS1,CDK5R1,DST,GPC2,CA8,CACNA1B,DDR1,CACNB2,CALM1,KALRN,NGB,TRIM41,CAPN3,CAST,HIP1R,RUNX1T1,CBR1,KYAT1,AIFM1,SCARB1,AP4M1,DCLK1,ARHGAP33,LGI1,RCBTB2,LSMEM2,RAB33A,NRXN3,PLAA,PPT2,COG1,CLTC,NGEF,FBXO7,NIPBL,RAB26,IQCK,BTF3L4,ABI3BP,IFFO1,ZFP28,ANKRD44,GDA,RGS6,CSF2RA,ARHGEF10,OSBPL3,SUSD5,ATRNL1,NCAN,RIMS4,CMTM5,PHF14,CTNND2,DCAF4,HDAC9,ARHGAP32,HDAC4,TOX,DAPK1,SPOCK2,SPATA2,YTHDC1,ELMSAN1,ZEB2,HEPH,MYEF2,CNIH3,COPS7A,DDX46,POM121,SNAP91,SACS,SV2B,SRGAP3,SEC16A,GRIN3A,SLC29A4,DMTF1,ATN1,PDCD6IP,MAMLD1,DYRK1A,WDPCP,PHC2,TMTC1,FRY,EFNB3,SUGP2,APH1A,MBNL2,AASS,SORBS3,TENM1,C8orf37,VPS13B,SEZ6,ZNF549,CLVS1,FAM198B,PTK2B,DLC1,FCGR3A,TOMM40L,FCGRT,STRADA,MED12L,KIAA1109,FGF14,TMEM164,AMOTL2,MEX3B,IP6K2,SYNCRIP,NOP56,DCTN2,SORBS1,FAM49B,OGA,MEGF10,TRAF3IP2,GAD1,AHCYL1,JPH4,ZNF274,ATP8A2,LRRC37A6P,DNER,GCNT2,TUBGCP4,SULT1C4,MSTN,USP19,PCDH17,GGT7,PPARGC1A,TNRC6A,INSM2,LUZP2,DCLK2,ADGRA3,PRUNE2,STON1,GPER1,CNTRL,GRIN2C,GRM1,GRM2,BTN2A1,LINC00839,AP4S1,RABL2A,RNFT2,GUCY1A1,MAN1B1,HMGB1,SYNPO,AGBL5,HNMT,NEGR1,LRRC75A,HSP90AA1,MSL1,RBPJ,KCND1,KCNJ3,KCNJ9,KCNK2,KLC1,STXBP5,LAMP2,PAXBP1,HECTD2,ZFYVE27,MAP2,AQP11,MBNL1,MBP,SYT9,IL17D,MDM4,AFF1,AFDN,MOV10,BLOC1S2,BCO1,MT3,RSPO2,MYH6,RTL5,NEXMIF,HNRNPM,NAP1L1,NBL1,NEK1,NELL2,NF1,NFIA,SLC11A2,SMIM11A,OPCML,OPHN1,P2RX7,PAK3,PBX1,PCDH9,PCSK1,ENPP2,GPR85,OLA1,NALCN,SEMA5B,CAMKV,TMIE,A2ML1,PLCB2,EXOSC10,ING3,SEPT4,NXPH1,DRAM2,MINDY2,CCDC144B,PPP3CC,PRKAB2,MAPK10,SLC26A11,PROX1,CNNM2,QRICH1,PSMD13,UHRF1BP1,BDNF-AS,PTHLH,PTPRE,PTPRO,FAM120C,PEX5,TUG1,ENOX1,RDX,SLC6A15,RGS3,RGS4,RGS12,ARHGEF10L,RPRD1A,CCDC102B,RPE,NEK11,GLDN,SGSM1,RPS6KA2,MAP6D1,CNTNAP3,RTN1,TRAPPC13,SATB1,DRAXIN,ATXN2,HOGA1,LINC00461,SCP2,PEAR1,NLGN4Y,SH3GL2,KIF16B,NTNG1,MAGI3,FNDC3A,ZNF365,EPN2,LRRC55,SLC6A9,SLC22A4,ZNF667,DMRTC1,IFT122,RIMS1,FAM126B,UNC80,KDM4B,WDTC1,LHFPL4,ZNF423,NPAS3,SPART,NFASC,LMO3,SRPK2,TROVE2,ITPRID2,STAU1,ZSCAN29,KANK1,ACSBG1,SYNE2,COBL,TACR1,PDLIM2,TBCEL,TBL1X,ANO4,ATMIN,EHBP1,ZEB1,AZIN2,TMEM151B,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DNAH7,CHST8,CRB1,AP4E1,BHLHB9,ERCC6L2,C5orf64,PIK3R5,TP53BP2,SEZ6L,TPM3,TRIO,STXBP4,NUTM2A,AMOT,UGT8,FLRT1,BCL2L13,BEST1,WRN,ZNF17,ZNF24,KCNT2,ZNF540,FMN2,GPR158-AS1,LYPD6,ZBTB38,POLR3H,SPIRE1,SYNC,PMEPA1,CADM2,XKR7,ADAMTS9,SLC17A7,FIP1L1,TMEM163,PARP11,PDSS2,RGS7BP,FZD3,DOCK8,SMIM8,CERS6,TRAM2-AS1,SNX14,SLC4A10,FAM198A" MicroRNA hsa-miR-412:mirSVR_lowEffct hsa-miR-412:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.73E-141 9.74E-138 3.01E-140 2.77E-139 397 1807 "DGCR6,KCNH8,ABHD6,NBAT1,FMNL2,TMCC3,ADD2,PTCHD1,KIDINS220,AP2A2,LRRC7,GOLGA7B,FAM135A,SYT13,KIF6,ZFAT,ANK2,ANK3,PI16,MAP4K3,SUGT1P4-STRA6LP-CCDC180,GPAM,PPFIA3,SHROOM2,CDC14B,ARNTL,CAPRIN2,ASPH,SLC2A11,CADM3,NOL4,BBS2,KSR1,CDK5R1,FUBP1,NIPA1,RAB29,CA12,CACNA1B,CACNA1E,CALM1,PTBP2,CAST,BRSK2,RUNX1T1,MTMR7,CBFA2T2,SCARB1,C1orf52,CDK11B,SEPT7,ARHGAP33,LRRFIP1,LGI1,CHGA,CHM,CHN1,CHN2,RAB33A,NRXN3,IGFBP7-AS1,DGCR9,AKAP7,AKAP6,SLC25A27,COL9A1,COL9A3,COL11A2,SLC4A8,IFFO1,ZFP28,FAM171B,RNF14,SLC32A1,ANKRD44,TENM4,PLCH2,PDE4DIP,SLITRK5,GREB1,ST18,RUBCN,DOCK4,GAPVD1,TCAF1,RIPOR2,KIAA0513,RASSF2,KIAA0586,TMEM170A,SCRN1,SPATA2,ELMSAN1,C8orf34,ZEB2,MFAP3L,RUSC2,COPS7A,ZC3H11A,GSDME,SMG7,WDR20,CCDC3,ZNF582-AS1,DMD,DNM2,DOCK2,ACOT8,ARRDC4,DYRK1A,E2F5,ANKRD46,HIPK3,PHF20L1,APH1A,AASS,KCTD3,COPS4,TNK2,PCOLCE2,HSD17B14,EPB41,RCAN2,ANKMY1,RPS6KC1,TAOK3,CORO2B,DLC1,ST3GAL6,GTF2IRD2,KIAA1109,FLT1,EFCAB2,WDR83,NBEA,POMT1,ARFGAP2,STAU2,PNMA2,HHIPL1,TRAF3IP2,ZMYND11,IP6K3,SIGLEC8,MTHFD2,C15orf41,ATP8A2,INPP5K,KIAA1841,GATM,ALDH1L1,ADAM28,GGT7,CRCP,DBF4,SPIN1,MSL3,LUZP2,DCLK2,GNAO1,GNAS,LILRA1,CCDC184,CECR2,PCLO,STMN2,GRB10,GRIA1,GRIA2,GRIA4,PLCD4,RFFL,ADAMTS13,GRM2,GRM5,AP4S1,FAM222A,HAS2,PACSIN2,HNRNPK,CPT1C,CELF5,HTR2A,MSL1,IDH3B,SCIN,ZNF678,INPP5B,LRRTM3,NME9,ITGAM,KCNJ9,KCNJ10,KCNJ11,KLHL23,KCNK1,KCNK2,KCNMA1,KIF5C,LIFR,HECTD2,MAG,LOC100128239,MAP4,MAP6,MARK1,MBD1,PPM1L,AFDN,WDR49,CD200,ZNF680,SAMD5,MT3,N6AMT1,SCG3,CCDC13,NEK1,NEUROD2,NODAL,NOVA1,NTRK2,NTRK3,ZNF713,P2RX7,ZNF827,PCSK2,PDE4B,PDE4D,CDK14,HERC2P3,FAM216A,PLP1,SMIM7,PLXNB3,PURG,PRIMPOL,ANKRD16,STRN3,PRRX1,PPM1B,VSTM2L,PRKACB,MAPK9,VPS13C,WBP1L,LRRC49,SNRK,TMEM104,CNTLN,DKFZp779M0652,PTPRH,ZSCAN2,TMEM231,RAD17,SH3TC2,DBX2,ZYG11B,TRIM68,ERI2,RFX5,RGR,RGS7,RGS12,ARHGEF10L,SEC61A2,RNASE1,RPRD1A,CCDC82,ARMC5,CARF,CCDC25,NEK11,PRR5L,TCP11L1,LGR4,PAQR6,ABCA11P,AMER2,SATB1,SCN8A,SCP2,TNFRSF19,SELL,ZNF821,GALNT10,MRAS,SH3BGR,SH3GL3,HKDC1,FBXO11,FNDC3A,BCAN,ST3GAL3,NUBPL,ZNF365,PEX26,PPP4R3A,DHX30,SLC6A1,KANSL3,SLC8A1,SLC8A3,SLC15A2,TMEM132D,SLCO1A2,SLC22A4,ARFGAP1,OGDHL,SMARCD3,RCOR3,RIMS1,SNAP25,MAPKBP1,PALLD,MYCBP2,ERC1,IDI2-AS1,PEG10,BEX1,KIF1B,DDN,ATP10B,CAMTA2,ITPRID2,SST,SSTR1,SSPO,ERBIN,ELOVL4,SEPT8,RGL1,ADHFE1,KANK1,STXBP1,FGD4,VAMP1,SYN2,TAC1,TACC1,EXOC7,VWA3A,TCF7L2,TRIM2,RPGRIP1L,SYNE1,DOCK9,TNS2,CYB561A3,SIRT1,SPX,AP4E1,SLC44A1,TJP1,TLL2,NR2E1,TMPO,FAM124A,SEZ6L,TPM3,C9orf85,TRPC1,TRPC3,FNDC5,TSN,SSBP2,TUB,HEPACAM,CADM1,UBE2H,UBE3A,UCHL1,FLRT2,CCDC14,WIPF1,P2RY12,AGMO,NDRG4,MKRN3,ZNF138,EML6,SYNC,WNK1,MAP3K12,DNALI1,CSDE1,STMN4,RNF103,FIP1L1,WIPF2,PARP11,CAMK1G,NUP214,FAM219B,ADAMTSL3,MSRB3,ST8SIA2" MicroRNA hsa-miR-1286:mirSVR_lowEffct hsa-miR-1286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.67E-141 1.50E-137 4.62E-140 4.26E-139 371 1586 "TTYH1,ABCF1,ACADM,CSMD2,SLC25A25,ADCY6,CCDC85A,ADD1,ADD2,MTA3,LRRC7,ARHGAP20,GOLGA7B,PITPNM2,AMPD2,PI16,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBB1,GAS7,AQP4,CASK,TMEFF1,ZFYVE28,ARHGDIA,LINC00173,CDK13,MARCH3,DACT3,NUMB,ATP1A1,MTMR9,ATP6V0A1,ADAM15,MPDZ,BCL2L2,BCL7A,NRP2,CDK5R1,SYNJ2,CACNA1G,CACNA1B,DIRAS1,NGB,CAMK2A,CH25H,BRSK2,CBFA2T2,LRBA,CDC25B,CDC42,CDH8,CASC2,SYNPR,EPS15L1,CPNE6,KIAA1549L,STOML1,QKI,HECTD1,PICK1,CNTN1,AKAP6,SUMF2,IFFO1,CNRIP1,CDC42BPB,PREPL,RBM39,CSF1R,MICAL2,IPCEF1,SIPA1L1,PLXNA4,PITPNM3,GREB1,CTNND2,NOS1AP,CYBB,MYADM,EARS2,KCTD8,IP6K1,CTIF,DCTN1,JAKMIP2,B3GAT3,MFAP3L,KIAA0753,RUSC2,TMEM130,DDX46,POM121,RABGAP1L,WDR20,KBTBD11,DLG2,CD99L2,DNM2,DOCK2,SLC12A6,DPH1,PDCD6IP,DSCAM,MAMLD1,FARSB,AASDH,ANKRD46,HIPK3,TMTC1,FSD1L,OPTN,MBNL2,ELN,C3orf18,EML1,EPHA5,MRPL10,ETV1,SIRPB1,CLVS1,ST3GAL6,CEP78,ZNF589,GTF2IRD2,KIAA1109,POLR1B,FGF11,FGF13,FGFR1,PRKAG2,UBE2E3,NELFCD,USP16,PDLIM5,FAM49B,ARFGAP2,KHDRBS3,CELF1,GPR153,ST6GALNAC3,SDCBP2,STAG2,IP6K3,GHDC,INPP5K,WASF3,LRRC37A6P,TUBGCP4,NTNG2,TTBK1,CRCP,MSL3,KDM2B,POLL,FUT10,STON1,TMEM121B,GRIK3,GRM2,CIT,BTN2A1,GUCY1A1,HAS2,PADI2,MAN1B1,ARHGAP19,BACH2,ACOT7,SYNPO,AGBL5,HPCA,ZDHHC15,HSD17B1,LRRC75A,HTR2A,GAREM2,TJAP1,LIX1,NME9,ITPKB,SLC35G1,KCNH1,KCNH2,KCNK3,KCNN2,CREG2,CAMK2N2,NCOA7,PACRG,SMAD1,GPR155,ZFYVE27,ADAM11,MDFI,CHIC1,MEF2C,KITLG,XRRA1,MMP16,MN1,CD200,CCDC80,PTOV1,CTNNA3,MXI1,MYCN,NDUFA5,NF1,NOVA1,NOVA2,OCRL,PAK3,ENPP2,PFKFB3,SERPINE2,CAMKV,PKM,HMGCLL1,PLXNB3,PNMA3,C11orf49,TRHDE,EPB41L4B,PPP2R5E,KANSL1,CEP41,MAPK4,MAPK9,DIRAS2,MASP1,CNNM2,BCAS3,WBP1L,CNTLN,PTHLH,PTPRE,ZSCAN2,PLEKHB2,FAM66C,RALGDS,SUSD4,RASGRF1,DBX2,BSDC1,MORC4,GTDC1,FIGN,RGS12,RNF220,TMLHE,PNMA8A,ZC3H14,TCP11L1,MEG3,KCNIP3,MAPK12,MIR124-2HG,HOGA1,FAM19A1,SCNN1D,SCP2,FNIP1,SEC14L1,TRIM46,SELL,ZNF821,FAM102A,FRMPD1,MYO18A,CHD9,ST3GAL3,NUBPL,CLSTN1,SLC1A7,LIMS2,RAB3GAP1,CCDC88A,ELMO2,SPHKAP,SMARCA4,IFT122,SNRPN,TMCC1,PDZRN3,UNC80,DOP1A,WDTC1,ZCCHC24,TSNAXIP1,ZHX3,LHFPL4,ERC1,TAB2,ATP10B,SMOC1,ST5,SEPT8,DIP2A,JMJD6,C3orf70,COBL,MLST8,FAM208A,ADGRL3,AGTPBP1,TBCEL,MGRN1,ANO4,TCEA1,EHBP1,ZEB1,TPCN2,WASHC4,CLASP1,AZIN2,SYNE1,NAT16,TMEM151B,AKNA,PUM2,USP32P1,HHIP,CDH22,SLC44A1,THRA,MTMR14,TMEM9,TJP1,TK2,ASXL3,KCTD2,KAT6B,PIK3R5,TPM2,TRO,STXBP4,TRPM2,ZMYND8,TMPRSS5,SSBP2,TTTY15,HIRA,RPL7L1,SLAIN1,PITPNB,WRN,KCNK12,ZIC3,TRIM9,ZFP41,ATP6V0E2,PLPP4,LYPD6,AMZ1,LAMP5,PMEPA1,EMSY,SLC38A1,GDPD5,PCDH15,NAV3,SLC17A7,CAB39L,WIPF2,MVB12B,DOCK8,ADAMTSL3,RNF170,RNF146,CPNE4" MicroRNA hsa-miR-1244:mirSVR_highEffct hsa-miR-1244:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.08E-141 2.29E-137 7.03E-140 6.48E-139 346 1383 "KCNH8,TKTL1,ARID1A,CSMD3,KLRC4,GALNT13,SORCS1,PLEKHH1,PWWP2A,MTUS1,KCTD16,C1QTNF3,CEP126,BCAR3,ABCD2,ARHGAP20,PCDH10,AMT,DPP10,ANK2,CCDC146,CNIH2,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,LGR5,TMEFF1,ASPH,ZBTB10,ATM,B3GALT2,CADM3,NOL4,CFLAR,SYNJ1,SCAPER,MTMR2,IL33,CALB1,ZNF555,CALM1,CANX,CH25H,CD38,CDC42,MAGI1,NUMBL,SRSF11,FOXN3,MS4A7,SYNPR,B4GALT6,NDST3,PLAA,CLCN3,NRXN1,QKI,NIPBL,CNTN1,ARMC8,ABI3BP,COX4I1,IGDCC3,FAM171B,SEC31B,ENTPD4,CREB5,NCOR1,LRIG1,MICAL2,PDE4DIP,PUM1,USP6NL,CCDC144A,FGFR1OP2,ARHGAP24,HDAC4,TOX,ZFYVE16,DAPK1,GIT2,PITPNC1,ZEB2,HEPH,FBXO25,ALKBH8,NTM,G3BP2,RABGAP1L,WDR20,DMD,DYNC1I1,ABI1,DYRK1A,GOLT1B,AASDH,EBF1,WDPCP,EDNRB,FCF1,SYT15,SEMA3D,SH3GLB1,FAM13A,ASB3,TENM1,PLEKHA1,TMEM35A,EML1,CALCRL,PAN3,EPHA5,GPHN,CEP85L,RCSD1,EYA1,F8,FAM198B,AMZ2,ATP8A1,FCGR1A,FCGR1B,ZSCAN30,FGF1,POLK,SUCO,CAP2,FOXM1,SGIP1,JKAMP,HVCN1,USP16,KHDRBS3,OGA,PHYHIPL,MEGF11,GABRA2,CHL1,GABRB3,GABRG2,ZMYND11,GALC,MTHFD2,DISC1,KIAA1841,MYOZ2,MSTN,PPARGC1A,GLS,PCDH11X,GNAL,FERMT2,LNX1,GPD2,GPM6A,PRLHR,GPR12,NUDT21,GPR37,GRIA4,ZNF496,CIT,LINC01551,SOX21,PSIP1,GUCY1B1,MAEL,ZHX1,MIER3,VSIG4,HMGB1,HMX1,CELF5,SMAP1,HTR5A,IGFBP1,USP54,NME9,ITPKB,METTL21A,KCNH2,KCNJ10,KCNN2,KCNN3,KLC1,KPNA5,HECTD2,MAP6,MARK1,MBNL1,MEIS2,XRRA1,MOBP,MOG,ADAM22,MTTP,MYO9A,NCF2,NF1,NOVA1,PCMT1,PCSK5,GPR85,FAM98B,ABCB1,SERPINE2,PIK3C2A,FAM218A,CCSER2,PLIN1,PLP1,HMGCLL1,PMP22,TRHDE,STRN3,SH3KBP1,MINDY2,CRLS1,PPP2R5E,PPP3CA,PPP3CB,PRKAB2,PRKCB,RAB39A,MAPK4,MAPK8,MAPK9,DIRAS2,VPS13C,WBP1L,SYTL2,GON4L,SNRK,PSMD13,CNTLN,MTMR10,SPDL1,PTN,TMEM260,ZSCAN32,PTPRN,PTPRZ1,ZNF615,QDPR,TMEM255A,RAD52,FAT4,OXR1,SLC6A15,RET,GTDC1,RGS4,NUDT11,EXD2,CCDC102B,RPL15,ADAL,LGR4,RYR3,CCDC112,ATXN7,SCN2A,FAM19A1,FNIP1,PPP1R9A,NTNG1,FBXO11,FNDC3A,FHOD3,SLC1A6,CCDC88A,TMEM132D,SLC20A2,GKAP1,USP33,TNIK,DOK5,KDM3A,ENKUR,EMC1,ZNF423,DBNDD2,CLASP2,POGZ,ITPRID2,EPB41L3,LARP4,NKAIN2,SS18,ERBIN,NXT2,SEPT8,DIP2A,KLHL7,PLCB1,COBL,ATP11A,ANKRD12,FAM208A,TBCEL,KLHL4,ATMIN,EHBP1,SATB2,WDR7,SIK3,DICER1,SPX,GZF1,TMPO,C9orf85,SYNPO2,TRIO,STXBP4,SSBP2,CLHC1,UBE3A,AMOT,VLDLR,NSD2,CLDND1,ZFP37,ZIC3,ZNF711,MICU3,KCNT2,TRIM9,ATP6V0E2,FMN2,ZNF138,ZNF225,EMSY,DNALI1,EVI5,PCDH15,AMN1,SMIM8,ZNF248,RNF170,FXR1,IFT88,NETO2,DPF3,CPNE4,FAM198A,SENP7" MicroRNA hsa-miR-3116:mirSVR_lowEffct hsa-miR-3116:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.23E-141 2.37E-137 7.26E-140 6.69E-139 388 1733 "CPNE2,DGCR6,SYN3,ACADM,NBAT1,GPRIN1,KLHL32,ADD1,SLC12A5,DPY19L2P4,AP2A2,CASKIN1,PCDH19,RTL9,PLA2G6,C1QTNF1,CARNS1,PCDH10,FAM135A,KIF6,OGT,ANK1,PI16,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB1,EPB41L5,APLP1,DGKD,ALS2,NT5C3B,VAT1L,PPFIA3,LGR5,SHROOM2,SEMA4G,MADD,CASK,MARK4,NUMB,ASTN1,CADM3,N4BP2L1,NOL4,RIPK1,LINC00847,BCHE,DNAJC27-AS1,SYNJ2,LINC00906,SCAPER,CACNA1G,MYRF,BAIAP3,IL33,MMD2,CA4,CA8,CACNA1E,DDR1,CALB1,HAP1,CAPN3,RUNX1T1,KYAT1,SYNGR3,LRRFIP1,LGI1,DLGAP1,CCPG1,SRSF11,CHM,CHN2,CHRM1,ARHGAP22,PLAA,QKI,COX4I1,SMARCAL1,ZFP28,SLC35F1,CPS1,PNKD,CDC42BPB,CRYBB1,ABCG1,SNCAIP,OSBPL3,CSNK1G3,VAC14-AS1,PDE4DIP,CMTM5,CTNND1,FAM131B,NOS1AP,CYBB,ARHGAP32,GAPVD1,SNPH,FRMPD4,IST1,DAPK3,SIRPA,KIAA0753,MAGI2,BLOC1S6,AK5,TMCC2,CHRDL1,DLG2,DMD,RPS6KL1,DNM2,WDPCP,EDN1,PHC2,TMTC1,SIDT2,YAF2,EGFR,EGR3,ELAVL3,TMEM35A,ENO2,EPB41L1,DMTN,GPHN,RASL12,EXTL1,SIRPB1,MRVI1,PTK2B,ZIC4,ATP8A1,CHST15,FDFT1,PPP1R1B,KIAA1109,SCARA3,HPCAL4,FOXG1,RGPD5,FOXM1,EVL,ZCCHC17,POMT1,CAMKK2,KHDRBS3,CELF1,TVP23A,SDCBP2,MEGF10,GABRA3,ZNF44,HBS1L,AHCYL1,B4GALNT1,ZNF274,MTHFD2,DISC1,SEPT9,WASF3,KIAA1841,NEU3,CYP46A1,GGT5,CRCP,MSL3,STARD3,ZNF638,GPT2,GP1BB,TDRKH,STON1,NUDT21,GRID1,GRIK5,ADAMTS8,GRM1,GRM2,GRM7,ZNF496,BTN2A1,LINC00839,LINC01551,AP4S1,RNFT2,GUCY1A1,IGSF21,PADI2,HRH3,BACH2,AGBL5,SHISA6,CELF5,ICA1,RAB41,RBPJ,LIX1,ITGAM,KCNA6,KCNC1,KCNJ10,KCNK1,GATD1,A1BG-AS1,KLC1,PAXBP1,SYTL4,NCOA7,LSS,MAN2A2,ZFYVE27,MAT2A,SYT9,ADAM11,SCAMP5,AFDN,XRRA1,MOBP,MSI1,BLOC1S2,ADAM22,PTOV1,LYRM9,MYO7A,FXYD7,NCAM1,NCF2,NFYA,NINJ2,NME4,NOVA1,PCBP3,NUCB2,OGDH,OPHN1,ZDHHC22,SNTG1,PCSK5,PRTG,PDE4D,PIRT,PFKP,NOMO2,CCSER2,XRN1,PKM,SMOX,PLP1,SLC25A23,PCDH18,C11orf49,PMP2,LRP12,PRRX1,POLR2F,POU6F1,PPARA,CCDC144B,PTPA,PRKAB2,HYDIN,MASP1,SLC22A23,SIDT1,CNTLN,UHRF1BP1,PXK,C1orf109,PEX2,TMEM231,SLC25A48,FAM66C,SUSD4,RASGRF1,TRIM68,PRRT2,DCUN1D2,C12orf49,EPHA10,MCMBP,PAQR6,MEG3,AMER2,SATB1,SCN2B,FAM19A1,PRCD,TNFRSF19,TRIM46,GALNT10,ASRGL1,RASA3,ITSN1,MYO18A,NTNG1,FNDC3A,CNKSR2,CTXN2,WDR37,SLC1A7,SLC6A1,KANSL3,LRRC55,SLC6A9,SLC8A2,NAPB,SCMH1,LGI3,GKAP1,MAST1,CDK5RAP2,MYH15,LIMCH1,CMTR2,FAIM2,PDZD2,ENKUR,ERC1,SPTAN1,ATP10B,STOX1,SMOC1,SSTR1,ZC4H2,INKA2,MAPK8IP3,MPRIP,CEP68,PHLDB1,GANAB,GSE1,FGD4,SYT1,SYT4,MTCL1,TAL1,FAM208A,PDLIM2,CNTN2,TBCEL,ANO4,SATB2,TPCN2,TRIM2,TGFBR3,ARL10,ENHO,DDHD1,TLR4,DAAM2,ANKRD24,PRRT1,ZNF346,AMACR,TMPRSS5,FAM155A,MGAT5B,VAV1,VLDLR,BEST1,WIPF1,ZIC1,LYPD6,AMZ1,TMEM198,ZNF213,DNALI1,SLC38A1,STMN4,PRDM8,SEMA3B,URM1,SNX27,EPM2A,FZD3,DOCK8,PAK5,FAM219B,RSPRY1,TIGD6,RNF170,ADAMTS10,SOCS4,LAS1L" MicroRNA hsa-miR-145*:mirSVR_lowEffct hsa-miR-145*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.04E-141 3.39E-137 1.03E-139 9.53E-139 374 1615 "TTYH1,ACADM,CLK4,C3orf14,EMILIN3,KLHL32,GALNT16,PSMG3-AS1,TMCC3,ADD2,SLC12A5,SORCS1,ADORA1,PWWP2A,PTCHD1,KIDINS220,BEND6,GPR158,HACE1,NME5,WDR35,OSBPL8,ZNF578,ALCAM,FAM135A,ZNF687,OGT,CDC42BPA,ANK2,CCDC146,USP28,PARG,BCAS1,API5,APP,ATP1B3,SNAI3-AS1,DNAJC27-AS1,BID,BMPR1B,DST,SYNJ2,CASTOR3,WASF1,LDLRAD4,PTBP2,VSTM2A,ISPD,SPAG9,PRC1,CBS,TMEM257,SEPT7,CDC42,ZMYM4,LRRFIP1,CDH18,LGI1,LOC730101,DLGAP1,NOG,SRSF11,CHN1,CHN2,CASC2,MS4A7,SYNPR,RAB3C,CHRNB2,LHX2,COG1,NGEF,TJP2,FADS2,ABCG2,BAG4,CREB5,HAPLN1,ANKRD44,GDA,SNCAIP,VCAN,PDE4DIP,PITPNM3,CFAP61,MYADM,FGFR1OP2,ZNF337,DGKB,IP6K1,YTHDC1,HEPH,FBXL5,KIAA0753,MAGI2,ZC3H11A,SGSM2,RABGAP1L,DLG2,DNAH9,CD99L2,DMTF1,DPH1,DRP2,ATN1,PDCD6IP,RCAN1,ARRDC4,DTNA,FAM78B,E2F5,USH1C,HIPK3,SYT15,SEMA3D,FAM13A,MBNL2,GOLGA7,TENM1,C8orf37,SEZ6,ZNF549,SPEG,EZH1,CLVS1,TAOK3,DLC1,ZNF589,FECH,SEC24B,MED12L,OLFM1,FHL1,UBE2E3,MEX3B,SEC23B,FOXF2,SGIP1,JKAMP,TMEM107,APOPT1,STAMBP,TPK1,PNMA2,B3GAT1,STAG2,MEGF10,GABRB3,HBS1L,IP6K3,C15orf41,LRRC37A6P,GATM,ALDH1L1,CYP46A1,MSL3,ZNF638,ADGRA3,LILRA1,CCDC184,NUDT21,EML4,CECR2,RAPGEF4,PRDM5,GRM8,FAM19A2,KAT7,ZBTB49,BVES,FAM107A,ADAMTS6,MAP4K5,MAEL,ELOVL5,SYNPO,HNF4G,EID2B,MSL1,ZIC5,KIAA1755,SCIN,LIX1,ITGAV,KCNJ9,KCNJ10,PAXBP1,NCOA7,MAP6,AQP11,SYT9,KCTD6,MMP16,MOG,ERICH3,MRPL42,ADAM22,CTNNA3,MYO5A,MYO6,NEXMIF,FXYD6,NF1,NINJ2,CNOT4,NTRK2,GPR88,P2RY1,GPR137C,KCNK10,PAK3,CNTN3,PDE4A,PDE4B,PDE4D,PDPK1,PDYN,CDK14,SERPINI1,KCTD15,SLC25A23,SMIM7,ING3,SEPT4,NXPH1,POU6F1,MED1,MINDY2,NKAIN4,RAB39A,MAPK4,DIRAS2,PRPSAP2,GDPD1,DCHS2,VPS13C,WBP1L,LAMA1,TMEM260,STK32A,ZIK1,PTPRB,OCIAD1,PTPRN2,C1orf109,PTPRZ1,CEP97,SLC25A48,IQSEC3,ZYG11B,REV3L,SLC25A36,PBRM1,RNASEL,RPRD1A,CCDC82,ZNF532,MYH14,YY1AP1,EPHA10,SPIN3,MCMBP,ATP8B4,ADAL,TCP11L1,ZNF354C,ATXN2,LINC00461,TNFRSF19,ZFP2,SUPT20H,NLGN4Y,ZFP30,SH3GL3,HKDC1,ST6GAL1,SLITRK3,NLGN1,RAB3GAP1,ARHGEF40,SLC12A2,SLC14A1,SLCO1A2,ZFP1,SMARCD3,SMARCE1,SNAP25,MBD5,SNRPN,PALLD,MYT1L,TNIK,SOX10,NMNAT2,CLUAP1,GLT8D1,ZNF423,RBM26,NFASC,LHPP,ATP10B,PBLD,COLGALT2,STOX1,ZNF302,SSTR1,LARP4,ERBIN,STAC2,KANK1,AJAP1,GSE1,RHBDL3,PLCB1,SYPL1,SYT1,TAC1,EXOC7,PDLIM2,ADGRL3,TBCEL,ANO4,TBX15,ATMIN,NEU4,SATB2,TRIM2,SZT2,WDR7,DOCK9,ARHGEF12,SIK3,RNF216P1,TMEM121,LEFTY2,AP4E1,TMEM9,SEZ6L,NPL,SYNPO2,METTL3,AMACR,TRO,TRPS1,TSC1,ANO5,RPL7L1,UCHL1,UGT8,SLAIN1,PITPNB,MEAF6,XRCC4,ZIC3,KCNT2,TRIM9,FMN2,ZSCAN26,MFF,CADM2,SLC38A1,PARP6,TMEM178A,CAB39L,FAM47E,MPPE1,DNAH10,PHTF2,CASC15,NUP214,IFT88,ST8SIA2,PRRT4,FAM198A" MicroRNA hsa-miR-549:mirSVR_lowEffct hsa-miR-549:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.82E-141 3.83E-137 1.17E-139 1.07E-138 356 1466 "ACLY,NCKAP5,XKR4,KLHL32,SORCS1,USP31,ESYT2,DPY19L2P4,NLGN4X,SLC44A5,PCDH19,ALAD,SMIM17,SEMA6A,ALCAM,UNC79,DPP10,LRCH2,ANXA7,PARG,GAS7,AMER3,USP37,AQP4,ARNTL,NUMB,ATM,STX16,NOL4,BMP7,NIPA1,CA8,CACNA1B,CACNA1E,CACNG1,CALM1,PTBP2,CAMK2G,ISPD,MAP7,RUNX1T1,CBR1,ZNF501,METTL6,CBFA2T2,CDC27,CDH10,MAGI1,DLGAP1,DIS3L,SRSF11,CHN1,SYNPR,CNOT8,C7orf61,RAB28,NRXN3,CLTA,ABCG2,NIPBL,CNTN1,ZNF521,CREM,CSF1,SUSD5,ATRNL1,SOCS5,PDE4DIP,PLXNA4,RASGEF1C,KIAA0040,DCAF4,EDRF1,DOCK4,KIAA0586,KCTD8,SPOCK2,ARMCX4,ARMCX2,SMG7,PLPPR4,SNAP91,WDR20,FAM107B,KBTBD11,DLG2,DLG3,DMD,HS3ST2,USP3,DOCK2,DPH1,ABI1,RCAN1,ECM2,DNAJB6,DNM1L,GOLT1B,FAM135B,ANKRD46,HIPK3,RASGRP1,TMTC1,FRY,RBM12,CELSR3,SUGP2,ABI2,EIF4G2,EIF5,PLEKHA1,RGS17,EN2,EPHA5,DENND4A,ZNF549,ADGRV1,EYA1,ARMCX1,WAC,CACNG3,TUBB4A,FCGRT,ZSCAN30,STRADA,FGF11,FGF13,TMEM164,PRKAG2,SYNCRIP,ANKFY1,SGIP1,SPECC1,UFM1,PRELID3A,ST6GALNAC3,DLL3,ZNF512,GABRA2,HBS1L,FAM120B,SALL3,MTHFD2,ZNF559,INPP5K,TUBGCP4,GFRA2,TOX3,KDM2B,GPM6B,DIPK1C,GPR37,GRB10,GRIA1,DIDO1,GRIA4,GRID1,GRIK2,NR3C1,GRM2,GRM5,COQ10A,WIF1,IRAK3,FRMD3,AGBL5,MSL1,IDH3A,NKD1,DOCK7,SCRT2,IL12A,BRINP3,ITPKB,KCNA1,OLFM3,KCNA4,KCNC1,KCNH1,KCNJ3,STXBP5,L1CAM,LAMP2,LMO2,PACRG,MARK3,MATN3,IL17D,MDM4,LRP1B,KCTD6,MOBP,SAMD5,MXI1,MYCN,LYRM9,MYO5A,NEXMIF,HNRNPM,NAP1L3,NCAM2,ZC3H12B,NEUROD1,NFYA,HCN1,GPR137C,PBX1,PDE1C,OLA1,ANLN,SNX10,XRN1,NLE1,ST8SIA5,TRHDE,CDIP1,PRRX1,SH3KBP1,POU3F2,MED1,PPP2R2C,PPP3CC,RANBP3L,EPDR1,PRPSAP2,RELN,APTX,SIDT1,QRICH1,PTN,TMEM260,PTPRO,PTX3,TUG1,TMEM231,ENOX1,RBBP6,RADX,VEPH1,KHDRBS2,GTDC1,RFX3,PRIMA1,PBRM1,SETD5,CYB561D1,ROBO2,FBXW7,ZC3H14,ATP8B4,PRR5L,ACER3,CNTNAP3,FAM182A,SCN2A,SOX6,CASC3,FOXRED1,KIF21A,ITSN1,FNDC3A,SLITRK3,NUBPL,ZNF365,RPH3A,SLC1A7,WDR47,FAM214B,KDM4D,SLC8A1,SLC12A2,TMEM132D,BTBD7,SPHKAP,EPC1,GKAP1,CDK5RAP2,MBD5,CABCOCO1,SNRPN,SON,PDZD2,SOX2,SOX11,SP2,CAND2,KDM4C,ERC1,KIF1B,MCF2L2,NPAS3,C11orf87,POGZ,LARP4,ELOVL4,RGL1,FGD4,SYNE2,PJA1,CAMTA1,UNC5D,AGTPBP1,TMEM136,VWA3A,DMXL2,TCF7L2,TPCN2,USP22,OBSL1,USP32P1,RNF175,TEK,SIRT1,ITGB3BP,AP4E1,MTMR14,HEY1,TJP1,TLR4,BEX4,TNS1,TP53BP2,ZNF384,SYNPO2,METTL3,TRO,CA14,TTTY15,TTC3,CADM1,EIF4ENIF1,PLEKHH2,ZNF709,ZNF708,ZNF28,CELF4,TMEM237,PLPPR5,INTS3,PMEPA1,PRDM2,RGMA,CSDE1,TUBA1A,VPS35L,PCDH15,NAV2,FZD3,MARCH8,PHTF2,ADAMTSL3,JMJD1C,SSPN,KLHDC1,IFT88,LAS1L" MicroRNA hsa-miR-21*:mirSVR_lowEffct hsa-miR-21*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.53E-141 4.23E-137 1.28E-139 1.18E-138 380 1667 "CPNE2,RALGAPA1,CSMD3,RNF157,SLC12A5,SORCS1,KIAA1211,ESYT2,BEND6,AP2A2,AP1B1,INTS2,OSBPL1A,TAOK1,SMIM17,SEMA6A,PCDH10,ANK3,PKP4,ALS2,FAM131A,CPNE5,ZFYVE28,TMEM108,SLC4A4,EIF4G3,ATP2B1,TTLL9,SNAI3-AS1,BBS2,BCL7A,GPR146,DST,MYRF,MMD2,BTRC,CACNA1E,CACNB4,DIRAS1,CAMK2A,CAMK2D,SHISA7,FMNL3,LGI1,CHN2,CNOT8,CLCN4,CLTA,FBXO7,MAP4K4,FAM149A,COL4A5,BTF3L4,SLC4A7,ACBD5,C2CD2,RBM39,CRMP1,ANKRD44,GDA,CSF1R,LRIG1,SUSD5,ATRNL1,IPCEF1,PLXNA4,ERC2,GREB1,PUM1,EDRF1,NOS1AP,GPRASP1,TOX,LIN54,DGKG,SCRN1,IP6K1,ARMCX4,YTHDC1,DNAJC6,CNIH3,KIAA0753,POM121,RHOBTB1,SV2B,SRGAP3,CHRDL1,RAB39B,DMPK,CDON,DPP6,TOM1,ABCC5,SGK2,SH3GLB1,FAM13A,SUGP2,APH1A,MBNL2,KMT5B,ABI2,EGR3,EML1,EPB41,EPB41L1,EPHA5,EPHB1,ENPP6,RABEPK,STX2,SCML2,DLC1,FECH,MED12L,GTF2IRD2,POLK,SUCO,CAP2,PCYOX1,SYNCRIP,FOXO3,EVL,ANKFY1,SGIP1,HVCN1,NPTN,ATP2C1,ZNF605,ERGIC3,KHDRBS3,NSG2,NSG1,PNMA2,MPP6,MEGF10,CHL1,GALNT15,GABRB3,GAD1,ZMYND11,RAPGEF6,MTHFD2,C15orf41,DISC1,INPP5K,WASF3,GFRA1,GFRA2,GHR,PPARGC1A,ZNF638,KDM2B,LUZP2,ADGRA3,PRUNE2,GPR12,PCLO,GRB10,GRIA1,DIDO1,GRM2,GRM5,TMEM25,ZBTB49,MAEL,PACSIN2,HRH3,HLF,ACOT7,HMGB1,GABARAPL2,SYNPO,TLX1,ZDHHC15,OPALIN,CELF5,SMAP1,FAAP20,ZNF546,GAREM2,IL6R,KCNB1,KCNJ5,KCNMA1,CREG2,KIF2A,KIF5C,KIT,IPO5,CYP27C1,SYTL4,PACRG,CLEC18A,MAP2,MARK1,MAT2A,MATN3,CHIC1,MEIS2,MID1,MMP16,MOBP,SAMD5,N6AMT1,MYO6,MYO9A,NAP1L1,NAP1L3,NCAM1,NCAM2,NEUROD1,NF1,DNHD1,NRCAM,NTRK2,NTRK3,ODF2,CLDN11,KCNK10,PCMT1,CDK18,GNG2,BEST3,PFKFB4,NOMO2,CCSER2,RETREG1,XRN1,KCTD15,PURG,PRIMPOL,PNMA3,STRN3,RETREG2,MINDY2,LRRN3,PPP2R5E,PRKACB,PKIA,PRKCG,PRKCZ,HYDIN,MASP1,DEF8,SNRK,TMEM104,QRICH1,WDR25,CNTLN,PTK2,DKFZp779M0652,PTPRE,TUG1,TMEM231,ATG16L1,RASGRF1,ZDHHC14,RET,RFX3,ARHGEF10L,RIC8B,RAVER2,ROBO1,CCDC25,RORB,SNX22,NEK11,PTGR2,ABCA11P,HUNK,ST6GALNAC6,ATAT1,RTKN,RTN1,RMI1,LRFN5,SCN8A,LINC00461,PPP1R9A,PPM1E,CPEB3,NTNG1,CNKSR2,NUBPL,WDR47,SLC6A1,SLC8A3,SLC9A5,KBTBD4,SLC12A2,SLC12A4,SLC14A1,ELMO2,BTBD7,SLC20A2,CPEB4,COA1,DMRTC1,UNC80,TNIK,ZCCHC24,CLUAP1,EMC1,SPP1,PBLD,COLGALT2,LARP4,NKAIN2,MPRIP,ZSCAN29,STXBP1,GSE1,MLC1,FGD4,ZC3H4,PRRC2C,VPS13A,DNAJC9,SYN2,TACC1,TMEM136,KLHL4,TBX15,EHBP1,SATB2,CUX2,TCF12,USP22,WDR7,AZIN2,PUM2,ARHGAP9,ZFPM2,ZMAT3,TGFBR3,ZNF106,CDH22,ARL10,HEY1,TLR4,ZFP91,TMOD1,C5orf64,KAT6B,TPM3,WBP2,SMUG1,TRH,AMACR,TSC1,TUB,TMEFF2,TUBB1,FLRT2,RICTOR,SLC13A3,ZBTB14,TRIM9,LYPD6,ZBTB38,ZNF154,REEP1,FSTL5,ANKS1B,SYNC,PRDM2,ADAMTS9,MDH1B,MVB12B,GOPC,UBE3B,KAT6A,CASC15,CERS6,FAM219B,ADAMTSL3,ZNF248,SSPN,CBLN2,ST8SIA2" MicroRNA hsa-miR-1231:mirSVR_lowEffct hsa-miR-1231:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.60E-141 4.27E-137 1.29E-139 1.19E-138 376 1633 "SERPINA3,ACADM,CLK4,KDM5D,CSMD2,XKR4,NDRG3,DSCAML1,ADCY6,ADD1,KIAA1211,SLC24A4,MTUS1,OSBPL8,ZNF578,ADGRF5,LRRC7,GOLGA7B,FAM135A,ZNF687,AMPD2,ANK1,PHF12,PPFIA1,CAPRIN2,NUMB,ATP6V0A1,BACH1,ADGRB2,LINC00847,BMPR1B,ARHGEF7,LINC00906,JAZF1,CDK5R2,CACNA1A,CACNA2D1,CALB2,CAMK2A,VXN,SPAG9,MAP7,NFS1,ZNF501,USP6,CDH10,MAGI1,CLGN,CACNA2D2,COPB2,FOXN3,NDST3,NRXN2,SULT4A1,SRP14-AS1,LY86,NIPBL,IGLON5,ARHGEF6,FAM149A,AKAP6,COL9A2,SLC4A8,TOGARAM2,MFSD4A,SEC31B,HAPLN1,CRY2,HINFP,ANKRD44,GDA,CLIP3,SNCAIP,RGS6,SEC24C,ATRNL1,VCAN,PDE4DIP,EDRF1,DOCK4,GAPVD1,TCAF1,ARHGAP24,TOX,KIAA0513,EARS2,ZNF337,IST1,DGKB,DAPK1,CTIF,PITPNC1,PLEKHM1,ELMO1,CNIH3,MFAP3L,HP1BP3,FBXL5,MAGI2,GSDME,PLPPR4,SNAP91,SPOCK3,SRGAP3,NTM,SGSM2,DLX1,DNM2,PDCD6IP,E2F5,EDN3,EDNRA,EDNRB,PHC2,SGK2,EFNB3,EBI3,EGR3,AASS,GOLGA7,SORBS3,PLEKHA1,TNK2,CERCAM,DCTN4,EIF1,ANKRD13B,DENND4A,ZNF549,SIRPB1,KATNAL1,MRVI1,ECSIT,EZH1,CLVS1,TBC1D16,CHST15,TOMM40L,FKTN,GORAB,FER,SPSB4,POLK,SUCO,MEX3B,HPCAL4,FOXM1,FLNC,PSD2,SORBS1,ADGRA1,DOT1L,NRG3,ABLIM2,GALR1,SALL3,NEK6,IP6K3,USP19,GLYR1,MSL3,ZNF638,LUZP2,GNAS,FERMT2,LILRB4,GPD2,GPR12,GPR17,GPR19,EML4,GRIA4,GRIN1,GRM7,BTN2A1,ZBTB49,LINC01551,ADAMTS6,RASSF8,HAS2,UBE2QL1,ATXN2L,TLX1,LRRC75A,GAREM2,KIAA1755,SCIN,IL6R,DIPK1A,INPP5B,INSM1,NME9,KCNA1,KCND1,KCNJ9,KCNJ16,KCNK3,KCNN3,CREG2,L1CAM,LAMA2,STMN1,HECTD2,GPR155,LYPLAL1,MBNL1,SYT9,LDLRAD3,MDM4,MEIS1,KCTD6,PPM1L,AFF1,GIT1,JAKMIP3,BLOC1S2,ADAM22,LAYN,RTL5,PABPC1L2A,MYT1,NF1,NME4,SMIM11A,NTRK3,OCRL,CHAMP1,OLR1,CLDN11,P2RX7,DPY19L2P2,PDE4D,DUSP26,GDAP1L1,SERPINI1,TMIE,PIK3R1,ZNF655,PLCL1,PLEC,PLIN1,PNMA3,PMP2,PMP22,ING3,POLR2F,POU6F1,PRKACB,PRKCB,MAPK3,MAPK10,MASP1,UHRF1BP1,PTPRB,PTPRD,FAM120C,ZNF844,FAM66C,SH3TC2,FAT4,ARID4A,RGS12,ARHGEF10L,SEC61A2,RNF220,RNH1,CARF,ROBO2,CCDC102B,NEK11,ATP8B4,SYNDIG1,ABCA11P,HUNK,CLIP1,RXRG,FAM182A,FAM192A,CSRNP3,ATXN2,LRRTM4,SCN8A,SMPD3,TRIM46,CASC3,NLGN4Y,PPP1R9A,SH3GL3,MYO18A,ST6GAL1,WDR37,ABLIM3,SLA,FAM81A,RPH3A,SLC6A1,SEPHS1,SLC8A1,RADIL,RAB3GAP1,CCDC88A,ARFGAP1,SMARCC2,CDK5RAP2,RCOR3,FAIM2,WDTC1,SOX5,KDM3A,SP2,ENKUR,GLT8D1,KDM4C,PEG10,IQSEC2,C11orf87,ATP10B,ITPRID2,ZNF302,SMOC1,SSTR2,NKAIN2,ERBIN,ST5,ELOVL4,SEPT8,KANK1,SULF2,FAM168A,ZFR2,VPS13A,NUDT10,PLCB1,SYP,SYT1,WWC1,TBL1X,TMEM136,ANO4,TBX15,TRIM2,PCDHB9,USP32P1,ARHGAP9,GPRIN3,AP4E1,AKTIP,BHLHB9,NR2E1,C5orf64,SMUG1,TRPM2,SSBP2,TTTY15,SGK3,RPL7L1,MTCH1,PLPPR2,VLDLR,BEST1,SF1,ZIC1,LYPD6,ZBTB38,EML6,SPIRE1,DNALI1,EVI5,LINC02210,SEMA3B,KCNAB1,FAM47E,RGS7BP,PAK5,JMJD1C,NETO1" MicroRNA hsa-miR-4329:mirSVR_lowEffct hsa-miR-4329:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-140 5.66E-137 1.71E-139 1.57E-138 392 1772 "VWA5B2,ABCF1,ASIC1,ACHE,AS3MT,NDRG2,KLHL32,ADD1,ERMN,KIAA1211,KIDINS220,OSBPL1A,WDR35,ALCAM,CDC42BPA,DPP10,FGD2,SUGT1P4-STRA6LP-CCDC180,USP37,CPNE5,CDC14B,PRX,CASK,ARHGDIA,PLA2G4C,ASCL1,MARCH3,ASPH,PCDHGB4,ATM,SLC4A4,ATP2B3,ZNF583,DOCK11,ADGRB2,RGS11,BCL2L2,CFLAR,KSR1,CDK5R1,ARHGEF7,LINC00906,AP1M1,GPC2,BTRC,CA8,CACNA1E,CACNG1,PTBP2,NGB,VXN,BRSK2,CCNH,INA,CBFA2T2,CD38,CDC42,CDH10,DLGAP2,CHM,ZBED5,CLCN3,CLU,QKI,SULT4A1,NIPBL,CNGA3,CNN3,AKAP6,SUMF2,COL9A1,MYRIP,ZFP28,SEC31B,PREPL,C2CD2,MICAL2,SUSD5,CNTNAP2,CST3,SLITRK5,PHF14,NRSN1,CCDC144A,CYBB,BOC,HDAC9,GPRASP1,EARS2,TBC1D5,INTS1,IST1,TOMM20,SPOCK2,PITPNC1,C2CD2L,MAGI2,GSDME,POM121,SMG7,NTM,FAM107B,KBTBD11,ZNF582-AS1,RAB39B,DYNC1I1,DNM2,ACOT8,DUSP9,MAMLD1,ABCC5,E2F5,AASDH,HIPK3,CNNM1,KLHL5,PHF20L1,MBNL2,EGR3,CALCRL,EPS8,CDKL3,RRAGB,FCGR1A,FKTN,STRADA,FGF12,PRKAG2,CAMSAP1,PCYOX1,SGIP1,NBEA,HVCN1,STAMBP,ZNF512,FYN,STAG2,MEGF10,GABRA1,CHL1,GABRB3,RAPGEF6,ZNF274,TMEM8B,KIAA1841,MYOZ2,GCNT2,GFAP,GFER,MALT1,MSL3,ZNF638,POLL,GPR12,CCDC184,EML4,STMN2,ADAMTS13,NR3C1,GRM3,FAM19A2,LINC01551,FAM107A,RNFT2,MUM1,IRAK3,LINC01102,HMGB1,SYNPO,HMGCR,HPCA,HTR2A,MSL1,FAM95B1,NKD1,GAREM2,ITPKB,SLC35G1,KCNJ10,KCNJ11,CREG2,KIF5A,KIFC3,KLRC2,TTYH2,NCOA7,GPR155,MAN2A2,ZFYVE27,MAT2A,LDLRAD3,MEIS2,MIA2,KITLG,MID1,MOBP,ERICH3,MXI1,LYRM9,MYO6,NAP1L1,NBL1,NCAM1,CCDC13,OTOGL,NFIX,VWA2,DNHD1,SLC11A2,NUCB2,NUMA1,LOC100128398,P2RY1,SNTG1,PCDHGC3,PCSK5,PDE2A,PDYN,OLA1,A2ML1,PLCB2,JAKMIP1,FTO,SLC25A23,MTRF1L,PURG,MAPKAP1,SDK2,MBOAT7,SLC36A4,PACSIN1,POU6F1,PPP2R2C,PPP3CB,PKN2,MAPK9,RELN,SNRK,MDGA2,PLPPR1,PTK2,PXK,OCIAD1,PTPRO,ZSCAN2,NKAIN1,QDPR,RAB5B,ACSS3,FAM66C,ARID4A,ZYG11B,TRIM68,RET,RGS3,RGS12,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,EXD2,GSTCD,CYB561D1,ROBO2,NEK11,ARMH4,ZC3H14,TCP11L1,LRRK2,RPS20,ABCA11P,S100B,SATB1,ATXN2,SCN8A,LINC00461,SCP2,SLC30A10,SUPT20H,SH3BGR,PPP1R9A,SH3GL3,ASAP3,MYO18A,NLGN1,ST3GAL3,CTXN2,FAM214B,SLC6A1,LRRC55,SLC8A2,YPEL4,SLC8A1,NAPB,TMEM132D,SORCS3,DMRTC1,ANKRD36,FAM219A,ENKUR,HECW1,KIF1B,NFASC,C11orf87,ITPRID2,SSTR1,ZC4H2,ST5,ADHFE1,STX1A,KANK1,STXBP1,PRRC2C,SYN2,DDHD2,TAF6,EXOC7,DNMBP,CAMSAP2,ADGRL3,SMG6,KLHL4,MGRN1,WSCD1,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TMEM151B,SLC19A3,GPRIN3,AHCYL2,ZFPM2,CRB1,AKTIP,GZF1,TMEM9,RELL2,BHLHB9,HEY2,RIMBP2,C5orf64,TP53BP2,NPL,PRMT8,TRIO,STXBP4,TRPS1,RUSC1,CA14,HEPACAM,RPL7L1,MEAF6,SLC13A3,XRCC4,ZIC2,KCNT2,REEP1,TMEM198,SPIRE1,LAMP5,SMARCAD1,EMSY,PRDM2,PRTFDC1,PCDH15,NAV2,PLSCR4,FZD3,DOCK8,ST7,MARCH8,FBXO36,ADAMTSL3,JMJD1C,RNF170,NETO2,LAS1L,SENP7" MicroRNA hsa-miR-374b*:mirSVR_lowEffct hsa-miR-374b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.05E-140 5.90E-137 1.77E-139 1.63E-138 397 1816 "SDE2,SYS1,NDRG2,TMEM132B,TMCC3,GALNT13,ADD3,PLEKHH1,PWWP2A,KIAA1211,PTCHD1,ADRB2,GPR158,HACE1,OSBPL1A,KIAA1324,WDR35,TXNDC16,CC2D2A,HFM1,LRRC7,SMIM17,SPOP,ALCAM,CEP126,ABCD2,FAM135A,ANK3,PPFIA1,PARG,CNTNAP1,APAF1,APBB2,UPRT,GPAM,ALS2,BCAS1,PPFIA3,APP,SHTN1,CDC14B,PPP4R4,PDXK,TMEM108,ATM,CCDC181,ATP2A2,ATP2B2,B3GALT2,ADAM15,PROM1,FUBP1,IL33,CA4,CACNA1D,LURAP1,CAMK2D,CANX,VSTM2A,BRSK2,MAP7,RUNX1T1,AIFM1,CD86,C1orf52,CDC27,CDH2,LGI1,NOG,NUMBL,DIS3L,CASC2,NDST3,RAB28,LY86,RAB26,FHL5,CNN3,ACBD5,SLC35F1,PREPL,CREB5,HAPLN1,HINFP,FEZ2,SUSD5,CTNND2,ST18,USP6NL,NOS1AP,KIAA0408,BOC,RIPOR2,MATR3,DGKB,DAPK1,IP6K1,BRINP1,DNAL1,DCC,SPATA2,C8orf34,ZEB2,KIAA0753,SNAP91,SACS,SPOCK3,ARNT2,KBTBD11,NR1D2,DPYSL2,ACOT8,PDCD6IP,DNAJB6,ABCC5,WDPCP,PHC2,ANKRD46,HIPK3,FEM1B,CNNM1,SEMA3D,RBM12,MBNL2,AASS,ASB3,ELN,TMEM35A,EIF1,EPHB1,RABEPK,SRRM1,CDHR1,TMEM74,KATNAL1,ADGRV1,EZH1,ABCA8,ZNF461,RPS6KC1,TMEM132C,ACSL4,SCML2,SEC24B,FGF13,HPCAL4,SEC23B,SYNCRIP,SGIP1,TMEM107,FAM49B,ARFGAP2,CAMKK2,ATP6V1H,DACH2,ST6GALNAC3,SARAF,OGA,DKK3,GALNT15,GAD2,ARPP21,IQGAP2,LRRC37A6P,DNER,GATM,ADAM28,CRCP,TCERG1,COPS8,KCNMB4,GPM6B,GPR22,GPR37,PCLO,STMN2,GRIA1,GRIA4,RFFL,GRM5,GRM8,KIF3A,BVES,PSIP1,GUCY1B1,IRAK3,RASSF8,LRRC75A,HSP90AA1,CELF5,SOWAHA,IL12A,INPP5B,OLFM3,KCNH2,KCNJ3,CREG2,STXBP5,KTN1,LAMP2,PAXBP1,SYTL4,ARHGAP12,SMAD1,MARK1,AQP11,EFHB,MDM4,MEIS1,KITLG,AFF1,MOG,ERICH3,COL28A1,SAMD5,SESN3,MYO9A,NAP1L1,NASP,NCAM1,NF1,OTOGL,NFYA,NINJ2,NKX2-2,NODAL,NOS1,DNHD1,NPPA,NTRK2,NTRK3,OPA1,CNTN3,PRTG,PDE4D,PENK,PFKFB3,PFKFB4,ZDHHC8,HERC2P3,ANLN,ZNF655,KCTD15,FAM216A,PLP1,STRN3,PMS2,EPB41L4B,NXPH1,LRRN3,PPP3CB,PRKCB,RAB39A,MAPK9,RELN,SLC22A23,SYTL2,LAMA1,GON4L,PSMD13,UHRF1BP1,BDNF-AS,PTHLH,PEX5,CEP97,ENOX1,DBX2,SLC6A15,REV3L,FIGN,RFX3,TTLL7,ZFHX4,CCDC82,CARF,CCDC25,YY1AP1,CCDC102B,NEK11,EPHA10,ATP8B4,PRR5L,SYNDIG1,RTN1,ZNF331,SEMA6D,SCN3A,SCP2,TNFRSF19,SLC30A10,IL17RB,SGK1,SCG5,SH3GL3,PPM1E,ARX,CPEB3,CNKSR2,NLGN1,SEC31A,NUBPL,SLC1A3,EPN2,KDM4D,BTBD7,CDK5RAP2,RCOR3,INAVA,MBD5,TMCC1,TRERF1,TSNAXIP1,SP2,ENKUR,UNC5B,CDK19,TSPYL2,RBM26,ZNF621,SSTR2,ZC4H2,ADHFE1,KLHL7,SYT11,RHBDL3,C3orf70,SYP,SYT1,C12orf76,TACC1,TACR1,KAZN,TAF9,UNC5D,FBXW11,KLHL4,ATMIN,DMXL2,SATB2,TCF7L2,ZEB1,RPGRIP1L,CLASP1,SZT2,SYNE1,RALYL,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,C18orf54,ITGB3BP,HHIP,AKTIP,SLC44A1,GZF1,NACC2,TLL2,TMPO,ANKRD20A2,ANO5,TTTY15,ZKSCAN5,HIRA,EIF4ENIF1,UBE2H,UBE3A,GORASP1,ZNF709,BCL2L13,VGF,XRCC4,ZIC1,ZIC2,AGMO,FMN2,ZNF154,TMEM237,ANKS1B,UPF3A,RNF103,PCDH15,URM1,PDSS2,RTN4,FBXO36,CERS6,TIGD6,NHSL1,NETO2,GAN,SENP7" MicroRNA hsa-miR-500:mirSVR_lowEffct hsa-miR-500:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-140 1.11E-136 3.32E-139 3.06E-138 406 1899 "SYN3,ACTN2,METAP1D,ADAR,TMEM132B,SLITRK1,ADCY6,ADD1,CDC7,AP2A2,INTS2,MTUS1,HACE1,OSBPL8,CC2D2A,ZNF578,ADGRF5,SEMA6A,CEP126,BCAR3,ZNF687,LCORL,PHYHD1,PPFIA3,APP,SHTN1,SFMBT2,PPP4R4,TMEM263,ARHGAP5,PDE8B,CAPRIN2,ASTN1,DDX3Y,CHID1,ZNF583,MTMR9,B3GALT2,NOL4,TTLL9,BCHE,RGS9,NRP2,CDK5R1,DST,BTK,RAB29,BTRC,CAMK2B,VXN,CAST,LDB2,CCNH,USP6,INA,LRBA,REPS2,CDH18,LARGE1,MAGI1,IGFN1,NOG,GPR37L1,CHN2,MS4A7,B4GALT6,JAM2,NRXN3,CLCN3,NRXN2,TPP1,FAM189A2,QKI,CNTN1,COL4A5,COL9A1,AKAP5,ABI3BP,RCHY1,ZNF521,IGDCC3,MFSD4A,HS3ST5,CPS1,SEC31B,CREM,HAPLN1,CLIP3,ABCG1,SNCAIP,ARHGEF10,SUSD5,NCAN,FAM169A,ERC2,ST18,RUBCN,USP6NL,CCDC144A,FGFR1OP2,KATNAL2,DCAF8,ZNF337,KCTD8,MAML1,DGKB,TMEM170A,SCRN1,IP6K1,DNAL1,YTHDC1,ZBTB24,FBXL5,KIAA0753,KIAA0319,CEP170,SNAP91,SPOCK3,NTM,RABGAP1L,DLX1,DMD,DPYSL2,ABI1,DNAJB6,DNM1L,EDNRB,TMTC1,PHF20L1,MBNL2,EIF5,ELAVL3,EML1,CALCRL,PAN3,USPL1,TUBD1,EPHA5,EPHB1,ENPP6,EPS8,CEP85L,ETV1,ANKMY1,ARMCX1,RACK1,TOMM40L,FKTN,KIAA1109,UBE2E3,FOLH1,SORBS1,SMC2,FAM49B,CAMKK2,ERGIC3,CELF1,DACH2,GABRG1,GAD1,NEK6,ALDH1L1,TUBGCP4,DBF4,GLI2,TNRC6A,MSL3,ZNF638,INSM2,KCNMB4,FUT10,EML4,GRIA2,GRIA4,GRM5,GRM7,CIT,FAM19A2,RNF165,GSTT2,PSIP1,RASSF8,ELOVL5,HPCA,C9orf129,CPT1C,HSP90AA1,HTR2A,LRRC25,ZIC5,LRRCC1,HES5,LIX1,ZNF385B,ITPKB,JAK2,KCND2,KCNJ10,KCNMA1,KCNN1,KIF5C,STXBP5,KTN1,LAMP2,INSYN2,HECTD2,NCOA7,LOC100128239,MAP2,MAPT,EFHB,MDM4,MEST,AFDN,MMP16,ADAM22,MSR1,N6AMT1,SCG3,MTR,RSPO2,MYO7A,P2RY13,NASP,NF1,DNHD1,SLC11A2,SMIM11A,NTRK2,OCRL,ZNF713,GLIPR1L2,PCDH9,PCSK5,SERPINI1,PIK3CD,ZNF655,A2ML1,KCTD15,PLCD1,PLP1,SMIM7,MTRF1L,PRRX1,FAT3,POU3F2,DRAM2,POU6F1,PPM1B,PPP2R2C,PPP3CB,RANBP3L,CEP41,RAB39A,PKN2,SIDT1,GON4L,SNRK,MDGA2,PTCH1,BDNF-AS,PTHLH,SPDL1,TMEM260,PTPRB,PTPRD,PTPRG,TUG1,USP47,PLEKHB2,SH3TC2,ENOX1,ZNF493,RASGRF2,VEPH1,MSANTD2,GAL3ST4,SLC6A15,GTDC1,RGR,RGS4,RGS12,SEC61A2,ZFHX4,RPE65,SNX22,ARMH4,UEVLD,ZNF671,ATP8B4,RPS20,FAM182A,RMI1,FOXRED2,SEMA6D,HOGA1,FAM19A1,FNIP1,SOX6,SELL,FOXRED1,SH3GL3,NTNG1,SHC4,CHD9,FBXO11,NLGN1,SEC31A,DZIP1,ZNF365,SEPHS1,RAB3GAP1,SLC8A3,CCDC88A,SLC11A1,SLC12A2,SLC14A1,SLCO1A2,GKAP1,SMARCE1,ANKRD36,INAVA,RIMS1,KIF13A,ZNF415,SNRPN,SOX11,ZSWIM8,ENKUR,HECW1,MYCBP2,IDI2-AS1,PEG10,SPTAN1,CDK19,TSPYL2,NPAS3,ATP10B,SMOC1,NKAIN2,CEP68,KANK1,SEPT3,STXBP1,GSE1,ZC3H4,ADAMTS17,C3orf70,SYN2,TACC1,TACR1,KAZN,MTCL1,CAMSAP2,FAM208A,UNC5D,TBCEL,IQCE,ZEB1,PSD3,SIRT1,DICER1-AS1,CRB1,C18orf54,TJP1,TK2,ACTR6,ANKRD24,KAT6B,TPD52,TPD52L2,TPM4,WBP2,ZNF384,RUNDC3B,STXBP4,PPIL6,TSN,ANKRD20A2,ANO5,TUBB1,CADM1,RPL7L1,AMOT,LINC00689,SLAIN1,BCL2L13,VAV1,MEAF6,WNT7A,MICU3,MKRN3,LYPD6,DNALI1,FAM47E,WNK2,RGS7BP,FAM13C,DOCK8,KAT6A,HNRNPA3,CERS6,VANGL2,KLHDC1,FRMD6,SLC4A10" MicroRNA hsa-miR-4255:mirSVR_lowEffct hsa-miR-4255:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.43E-140 1.36E-136 4.07E-139 3.75E-138 373 1613 "RALGAPA1,SERPINA3,ASPHD1,NBAT1,FAM43B,KLHL32,KLRC4,SLITRK1,ADD2,GRAMD1B,ADORA1,OLMALINC,AP2A2,OSBPL1A,ALCAM,UNC79,FAM135A,AMPD2,CDC42BPA,DPP10,ANK2,ANK3,PPFIA1,GPAM,VAT1L,TNRC6C,API5,LGR5,MIER1,CASK,CDK13,ZSCAN18,CCAR2,DDX3Y,ATP2A2,N4BP2L1,RIPK1,BCHE,IL33,DDR1,CACNB4,CALB1,KALRN,PTBP2,CAMK2A,CAMK2B,VSTM2A,CAST,CBLN1,CBR1,CBFA2T2,LRBA,REPS2,CDC42,CDH2,DCLK1,MAGI1,CDO1,TIGD7,CHGA,NDST3,KMT2C,ZFYVE9,CLTA,QKI,IGLON5,CNN3,MYRIP,CPS1,PNKD,SEC31B,ANKRD44,CSF1,LRRC3B,CSNK1G3,FAM169A,SLITRK5,PPP1R16B,CTH,CTNND1,PUM1,RUBCN,NOS1AP,BOC,DOCK4,KIAA0513,ZFYVE16,LONRF1,LIN54,IP6K1,BRINP1,GIT2,JAKMIP2,ZEB2,MAGI2,KLHL3,SNAP91,SRGAP3,DMD,DYNC1I1,CDON,DMTF1,SLC25A18,PDCD6IP,DTNA,DTNB,ECM2,ABCC5,DNM1L,E2F5,EDN3,EDNRA,CNNM1,KLHL5,TMTC1,RBM12,YAF2,FAM13A,EGFR,ABI2,RASA4,KCTD3,ELAVL2,ELAVL3,STARD3NL,SRRM1,DENND4A,DUSP27,CLVS1,ABCA8,ACSL4,DLC1,CHST15,FCGRT,SEC24B,FER,FGF11,PRKAG2,POLK,FOXG1,FOXF2,SYNCRIP,FOXO3,C2orf88,ATP2C1,STAU2,DKK3,MEGF10,GABRG2,BRPF3,ZMYND11,ARPP21,NEK6,NCKAP1,IQGAP2,ZNF559,C15orf41,LRRC37A6P,IGSF5,TUBA8,MSTN,ARFIP1,MALT1,KIRREL3,TTBK1,COPS8,SPIN1,DCLK2,LNX1,GPM6B,PCLO,ATP2B1-AS1,GRIA2,DIDO1,PLCD4,RFFL,FAM19A2,LINGO1,ADAMTS6,BACH2,MIER3,ELOVL5,NEGR1,MSL1,IFI16,PLD5,ITGAV,SLC35G1,METTL21A,KCNJ10,KCNK2,KIF2A,KIF5C,KTN1,LIFR,VWA5A,ZNF667-AS1,MAN2A2,LYPLAL1,MAT2A,MATN2,MATN3,MEF2C,MEIS2,KITLG,AFDN,MMP16,MOBP,MRPL42,RSPO2,MYO9A,NAP1L2,NCAM2,NEK1,VWA2,NOVA1,SLC11A2,NTRK3,SETD4,P2RY1,GPR137C,TREM2,GLIPR1L2,PBX1,PDE3A,ENPP2,FAM98B,NLGN3,GDAP1L1,SERPINE2,TMIE,ANLN,XRN1,NLE1,PLCL1,PLEC,PLXNB1,PRIMPOL,PMP22,PSAT1,ING3,RETREG2,FA2H,MINDY2,CRLS1,PPP2R5E,PPP3CB,RASGEF1B,PKN2,EPDR1,MASP1,LRRC49,APTX,MDGA2,PTCH1,UHRF1BP1,PTK2,ZSCAN32,PTPN13,PTPRZ1,NKAIN1,TTC13,PPP2R3C,USP47,FAT4,KHDRBS2,RDX,REV3L,RFX3,RFX4,SEC61A2,RPRD1A,FBXW7,BAALC,GLDN,LGR4,HSD11B1L,ATXN2,ELMOD1,SOX6,TRIM46,TRA2B,SGK1,SH3GL3,CHD9,FBXO11,CTXN2,DZIP1,NUBPL,SLC1A3,BTBD3,SLC6A1,KANSL3,SLC8A3,BTBD7,SLC22A4,SORCS3,INTS9,PALLD,DOP1A,SOX2,SP4,NMNAT2,KDM4C,TSPYL2,NPAS3,NFASC,POGZ,COLGALT2,ITPRID2,SSTR1,SSTR2,FCHO1,SEPT8,CEP68,FGD4,VAMP1,VPS13A,ARC,SYT1,ANKRD28,SYT4,MTCL1,UNC5D,TBCEL,TMEM136,KLHL4,EHBP1,TCF4,SATB2,CUX2,ZEB1,WDR7,SYNE1,RALYL,ARHGEF12,PCDHA5,FRYL,SIRT1,CRB1,ITGB3BP,AP4E1,TIAM1,TLL2,TMOD1,RIMBP2,C5orf64,PIK3R5,TPD52,DCBLD1,TSC1,TTC3,ZKSCAN5,ZNF709,BCL2L13,BEST1,ZNF781,RICTOR,SLC13A3,TCEAL7,CADM2,LRP8,STOX2,ADAMTS9,NAV3,KCNAB1,PLSCR4,PDSS2,AMN1,FZD3,ZNF248,NHSL1,FXR1" MicroRNA hsa-miR-877:mirSVR_lowEffct hsa-miR-877:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.69E-140 1.51E-136 4.50E-139 4.15E-138 364 1538 "DPF1,KCNH8,ASPHD1,ACADM,ASIC1,CSMD2,CSMD3,TMEM132B,GALNT13,ADD3,SORCS1,KIAA1211,RNF150,ESYT2,NLGN4X,MTA3,SLC44A5,ZNF608,KLHL13,CASKIN1,KIAA1324,ALCAM,FAM135A,KCNT1,MRTFA,KIF6,BIN1,EP400,CCDC146,PARG,EPB41L5,DGKZ,ALS2,TNRC6C,SEMA4G,MADD,CADPS,ASPH,ASTN1,TMEM108,ATM,SLC4A4,SLC2A11,MTMR9,BCL2L2,BCS1L,ZNF599,CFLAR,KSR1,NIPA1,GPC2,BSN,WASF1,PTBP2,SLC25A14,PRC1,AIFM1,ENTPD6,CDC25B,EVI5L,CACNA2D2,ASIC3,CNOT8,NMT2,NGEF,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,SLC4A7,IGDCC3,PNKD,GDA,ABCG1,CS,SNCAIP,CSF1R,MICAL2,ATRNL1,FAM169A,ERC2,CMTM5,CCDC144A,HDAC9,ZNF337,PITPNC1,RHOBTB1,SGSM2,WDR20,KBTBD11,DLG2,DMD,DNAH9,DMTF1,GNE,FAM78B,MAMLD1,DNAJB6,DYRK1A,ABCC9,HEYL,TMTC1,SIDT2,PHF20L1,KMT5B,EIF4G2,ELN,USPL1,ENO2,EPB41L1,RCAN2,LRRC17,DENND4A,MRPL37,ZNF461,ZMYND10,FCGRT,FECH,FGF1,FGFR1,AMOTL2,ANKFY1,SGIP1,SLC37A3,TACC2,FAM49B,ATP6V1H,ERGIC3,KHDRBS3,GPR153,PNMA2,SARAF,STAG2,GALNT15,GABRG1,GALC,ARPP21,ERAP1,C15orf41,DISC1,SULT1C4,LYVE1,GJB1,GK,GLI2,AIFM3,ADGRA3,GPR12,MCHR1,TMEM121B,GRIA1,DIDO1,ADAMTS13,GRM7,BTN2A1,KIF3A,LINC00839,TMEM25,AP4S1,CELF3,HAS2,GABARAPL2,SYNPO,AGBL5,HNRNPK,OPALIN,TCEAL6,HSPA1L,HSP90AA1,SMAP1,HTR5A,LINC00667,TJAP1,DISP2,HES5,SCRT2,INSM1,LRRTM3,SLC35G1,KCNC1,KCNF1,KCNH2,KCNJ10,KCNK1,KCNK2,KIF5C,L1CAM,LAMP2,SYTL4,PIK3AP1,MAN2A2,MARK1,LRP1B,ZNF680,TAGLN3,MTTP,LAYN,MYO9A,ZNF862,FXYD7,NCAM1,ZC3H12B,NEUROD1,ALDH1L2,NME4,SETD4,PAX6,PBX1,PDE1C,PDE4D,PDYN,GNG2,ZFYVE21,ST8SIA5,PURG,MAPKAP1,LRP12,EPB41L4B,FA2H,FAT3,CCDC144B,PPP2R5C,PRKACB,MAPK4,HYDIN,MASP1,SAMD9,PIGG,PLPPR1,PTPN13,PTPRB,PTPRD,NKAIN1,CEP97,SH3TC2,RASGRF2,ARID4A,ZDHHC14,SLC6A15,ZYG11B,DPF2,RFX5,PRIMA1,TTLL7,TMLHE,ROBO1,YY1AP1,MAP6D1,LRRK2,MEG3,ATAT1,KCNIP3,WLS,RXRG,DGLUCY,SATB1,SCN4B,FAM19A1,ELMOD1,SEC14L1,CASC3,GALNT10,COPZ1,NLGN4Y,PPP1R9A,SH3GL3,SHC4,BCAN,WDR37,SLA,SLC1A3,FAM81A,PPP4R3A,EPN2,RUFY2,SLC8A1,SLC12A2,NAPB,EFHD1,BTBD7,SLCO1A2,SPHKAP,LGI3,IFT122,ANKRD36,INAVA,SNRPN,TMCC1,KDM4B,SON,BDP1,KDM4C,TEX2,KIF1B,ZBTB43,NPAS3,NFASC,ITPRID2,SYT11,JMJD6,ARHGEF9,CAMSAP2,WWC1,VWA3A,SIN3B,RPGRIP1L,TCF12,NAT16,PCDHB9,PCDHB6,AKNA,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,RNF216P1,CRB1,MTMR14,TMEM9,ERCC6L2,HEY2,PRRT1,KAT6B,DOK6,ZNF384,ZNF346,TRPS1,FNDC5,DCBLD1,CA14,TTTY15,LRTM2,FLRT2,MEAF6,CLDND1,SLC13A3,ZNF24,ZNF32,TRIM9,AGMO,NDRG4,CELF4,REEP1,DHX33,SLC30A4,PRDM2,PRTFDC1,DNALI1,SLC17A7,PCBP4,WIPF2,WNK3,C12orf4,FZD3,UBE3B,RNF170,SSPN,IFT88" MicroRNA hsa-miR-302b*:mirSVR_highEffct hsa-miR-302b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.27E-140 2.40E-136 7.11E-139 6.55E-138 349 1417 "KDM5D,KLHL32,SLITRK1,GALNT13,ERMN,PWWP2A,KIAA1211,ADRB2,ZNF608,INTS2,MTUS1,CASKIN1,NME5,NR0B1,C1QTNF3,LRRC7,ALCAM,ABCD2,FAM135A,PITPNM2,OGT,CDC42BPA,ANK1,ANK2,ANK3,USP28,PPFIA1,APBB2,MAGEE2,TNRC6C,APP,PPP4R4,PDXK,IGDCC4,TMEFF1,ARNTL,RGS20,ATP1A2,ATP2B1,ZNF583,N4BP2L1,DOCK11,BACH1,ADGRB3,SYNJ1,SCAPER,WASF1,KALRN,PTBP2,CAMK2D,ISPD,RUNX1T1,METTL6,REPS2,TIGD7,CIART,CFL2,SRSF11,SYNPR,NRXN3,CLTC,ABCG2,QKI,SLC25A27,SLC4A8,ABI3BP,IGDCC3,CNRIP1,CP,CHD1L,PREPL,HINFP,GDA,SNCAIP,CSF1,ARHGEF10,OSBPL3,VCAN,PDE4DIP,APPL1,UBXN2A,CTNND2,DCAF4,RUBCN,DOCK4,HDAC9,GPRASP1,ARHGAP32,FRMPD4,PHF19,EARS2,MATR3,KIAA0586,IST1,PITPNC1,DNAJC6,DCTN1,MYEF2,LYPD1,PLPPR4,CHRDL1,DLG2,NR1D2,CPEB2,CASP8AP2,ABI1,DSCAM,ABCC9,GOLT1B,ANKRD46,SEMA3D,EEF1D,PHF20L1,MBNL2,EGR3,TENM1,PLEKHA1,CALCRL,TUBD1,LRRC17,KCNMB2,GPHN,FAM198B,TAOK3,EFEMP1,DLC1,ST3GAL6,CEP78,SLC9B2,FGF13,FGFR1,FGFR3,CAMSAP1,MEX3B,FOXF2,C2orf88,NBEA,FAM49B,ATP2C1,KHDRBS3,DACH2,STAU2,NRG3,ABLIM2,STAG2,GABRA2,GABRB3,GAD1,AHCYL1,SALL3,NCKAP1,C15orf41,DISC1,IGSF5,ADAM28,MALT1,DBF4,SPIN1,TNRC6A,ZNF638,FERMT2,GPR22,EML4,RAPGEF4,GRIA2,GRIA4,PLCD4,NR3C1,GRM1,PRDM5,GRM7,FAM19A2,RNF165,LINC01551,ATG4C,MIER3,HMGCR,HSF2,ZNF546,LRRCC1,JAK2,KCNJ3,KCNK2,KCNMA1,KIT,CYP27C1,LAMP2,HECTD2,SMAD1,PIK3AP1,LYPLAL1,MDM4,MEIS1,AFDN,ZNF680,SESN3,CCDC80,MT1M,MTTP,P2RY13,NCAM1,NDUFA5,NF1,OTOGL,NODAL,NOS1,LRIT2,HCN1,NUCB2,CHAMP1,OPHN1,PAX6,PCDH9,PDCD2,PDE4D,PDGFRA,GNG2,SNX10,RETREG1,PLP1,HMGCLL1,PURG,ANKRD16,TRHDE,PRRX1,ING3,EPB41L4B,FA2H,POU3F2,PPM1B,PCDHB17P,PPP2R5C,KANSL1,GRAMD1C,DIRAS2,PROX1,RELN,SPDL1,TMEM260,ZSCAN32,PTPRB,TMEM231,SH3TC2,NWD1,OXR1,RASGRF2,RBBP8,RADX,KHDRBS2,MSANTD2,RGS7,PBRM1,ZFHX4,RAVER2,ROBO2,RPL15,LRRK2,SOX8,RYR3,SCN3A,SFPQ,SUPT20H,SGK1,ZFP30,DOCK10,SHC4,MAGI3,FBXO11,FNDC3A,FHOD3,SEC31A,SLC1A3,PPP4R3A,EPN2,RUFY2,FAM214B,RADIL,SHANK2,ATF7IP,SLIT1,SMARCC2,ANKRD36,MBD5,SNRPN,PALLD,PDZRN3,SON,BDP1,EMC1,TEX2,ZNF423,ZC3H13,SPTAN1,CDK19,MCF2L2,SRPK2,ATP10B,TROVE2,SSTR2,LARP4,ELOVL4,DIP2A,SYT11,VPS13A,SYPL1,DDHD2,ATMIN,TCEA1,TRIM2,WDR7,RALYL,SIK3,ZMAT3,SLC44A1,ASXL3,TLL2,ERCC6L2,C5orf64,TNS1,TPM1,METTL3,DCBLD1,RPL7L1,FRRS1L,ZNF781,ZNF711,ZNF17,ZNF23,ZNF45,CELF4,FSTL5,EML6,SMARCAD1,UPF3A,WNK1,MFF,CADM2,PCDH15,KCNAB1,WNK3,PLSCR4,PDSS2,EPM2A,DOCK8,JMJD1C,KLHDC1,RNF146,CBLN2,ST8SIA2" MicroRNA hsa-miR-449b*:mirSVR_lowEffct hsa-miR-449b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.57E-140 2.57E-136 7.59E-139 6.99E-138 394 1797 "VWA5B2,RALGAPA1,CSMD3,ADAR,ADD1,ADD2,SORCS1,GRAMD1B,USP31,DPY19L2P4,MTUS1,OSBPL1A,KIAA1324,TAOK1,C1QTNF3,SMIM17,SYT13,ZNF687,AMPD2,ANK1,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,APBA2,APBB1,DGKZ,FAM131A,PHYHD1,PPFIA3,USP37,SHTN1,IGDCC4,ARHGAP5,ARNTL,LINC00173,MARCH3,ZSCAN18,STX16,DPY19L3,ADAM15,BCL2L2,BCL7A,KSR1,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,NIPA1,GPC2,WASF1,MMD2,CH25H,CBR1,ZNF501,USP6,ENTPD6,LOC730101,TIGD7,CCPG1,CHN2,RAB3C,TAOK2,DLGAP3,NRXN3,CLCN3,CLTA,C4orf33,SULT4A1,IGLON5,ARHGEF6,CNR1,PCYT1B,ZNF521,CHD1L,SLC35F1,CREM,CRY2,ANKRD44,GDA,TRIM69,SNCAIP,CSF1R,MICAL2,ATRNL1,SOCS5,CNTNAP2,APPL1,CMTM5,ARHGEF4,NRSN1,EDRF1,MYADM,HDAC4,TOX,KIAA0586,DGKG,IP6K1,DCC,ZBTB24,RUSC2,COPS7A,SNAP91,SV2B,SRGAP3,SGSM2,WDR20,CHRDL1,DLG2,DLG3,DLX1,EXOG,GRIN3A,HS3ST4,USP3,CPEB2,DRP2,ATN1,DTNA,DYRK1A,EDNRA,EDNRB,SGK2,SYT15,RASGRP1,RBM12,YAF2,EIF5,EPB41,STX2,VPS26C,ANKMY1,EZH1,WAC,TOMM40L,FDFT1,ZNF589,FGF1,AMOTL2,PRKAG2,POLK,SYNCRIP,PSD2,PDLIM5,B3GAT1,SARAF,HHIPL1,ABLIM2,OGA,STAG2,GABBR1,GALNT15,CAB39,GAD1,GAD2,HBS1L,BRPF3,FAM120B,B4GALNT1,JPH4,ERAP1,SIGLEC8,GATM,TUBGCP4,GFER,CSDC2,GK,OS9,DCLK2,GPD2,GPM6B,CCDC184,GPR17,ADAP1,GPER1,PCLO,GRIA2,PLCD4,SPACA9,ADAMTS13,ATE1,ZNF496,BTN2A1,LINC00839,TMEM25,MFSD2A,RNFT2,HPS5,GPR45,ARHGAP19,OPALIN,HSD17B1,HSP90AA1,FAAP20,EID2B,IRF8,IDH3A,IDH3B,TJAP1,SCIN,SLC6A17,ITGA7,OLFM3,KCNC2,KCNJ3,KCNJ5,KCNK3,A1BG-AS1,IPO5,STXBP5,STMN1,MAP2,CHIC1,MEIS1,SRSF12,KITLG,AFDN,MMP16,MOBP,GIT1,MSRA,MT3,N6AMT1,DDX25,MTR,NAP1L1,NASP,RCOR2,NELL1,NEK1,NFYA,NHLH1,NPTX1,SMIM11A,NTRK2,NTRK3,NUCB2,OPA1,ZNF713,CDK18,PDE3A,PDE4D,PFKFB2,ZNF655,CCSER2,PLCL1,FTO,PLIN1,PDZRN4,POU6F1,CRLS1,PPP3CA,PKN2,WBP1L,ANKHD1,BDNF-AS,ZIK1,PTPRD,PTPRO,USP47,SH3TC2,ATG16L1,OXR1,ZDHHC14,GTDC1,ARHGEF10L,NUDT11,ARMC5,GSTCD,CYB561D1,KIRREL1,ROBO2,SNX22,NEK11,EPHA10,BAALC,MCMBP,GLDN,EMID1,CNTNAP3,HUNK,WLS,RTN1,SCN3A,SCP2,SEC14L1,CASC3,SLC2A5,RUFY2,RAB3GAP1,SLC8A3,SIRT2,SLC12A2,TMEM132D,BTBD7,SLCO1A2,IFT122,MBD5,TMCC1,DOP1A,WDTC1,ZSWIM8,SP4,GLT8D1,HECW1,KIF1B,RBM26,NPAS3,SPART,C11orf87,TROVE2,EPB41L3,ZC4H2,LARP4,ZSCAN29,SEPT8,CEP68,SEPT3,MLC1,SUPT5H,PRRC2C,ZFR2,SYT4,ANKRD12,UNC5D,WWC1,ATMIN,KIAA0930,TCF7,TPCN2,AZIN2,DOCK9,PHF24,TMEM151B,PCDHB3,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,CYB561A3,FAM200B,ZFPM2,CRB1,GPR161,THBS4,ACTR6,TLL2,PRRT1,C5orf64,RGMB,NR2C2,PRMT8,TRO,STXBP4,RUSC1,ZKSCAN5,ZNF610,AMOT,CCDC14,VLDLR,BEST1,WIPF1,SLC13A3,XPO1,ZNF24,KCNT2,TRIM9,REEP1,SPIRE1,MEIS3,SLC30A3,MAP3K12,PRDM2,GDPD5,HPS4,VPS35L,GAL3ST3,FAM47E,PDSS2,EPM2A,DOCK8,FBXO36,CAMK1G,NHSL1,CBLN2,SOCS4,GAN,ZNF30" MicroRNA hsa-miR-4309:mirSVR_lowEffct hsa-miR-4309:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.97E-140 2.79E-136 8.23E-139 7.58E-138 370 1591 "CLK4,XKR4,ADAR,PLEKHG5,ADD2,SLC12A5,GRAMD1B,KIDINS220,SNX32,KCTD16,KIAA1324,OSBPL8,TAOK1,KIF6,ANK2,FGD2,PHF12,APBA2,CDC14B,MIER1,KIAA1614,SEMA4G,MADD,ARHGAP5,ARNTL,LINC00173,DACT3,PCDHGB4,NUMB,ATP1A2,SLC4A4,EIF4G3,ATP2A2,ATP2B2,ATP2B3,DOCK11,ADAM15,BACH1,ADGRB2,RGS9,SYNJ2,SCAPER,GPC2,BSN,CA4,CA12,CACNB2,PTBP2,CAMK2G,VSTM2A,SPAG9,NFS1,CBLN1,METTL6,CD86,SYNGR3,NEURL1,REPS2,CHGA,CHM,ZBED5,TAOK2,NRXN3,CLTC,MAP4K4,LY86,TMEM155,AKAP6,RCHY1,SMARCAL1,MYRIP,MFSD4A,CP,SEC31B,PREPL,AKAP12,CSF2RA,CSNK1E,FAM169A,CFAP61,CTNND1,EDRF1,CX3CR1,MYADM,ARHGAP32,EARS2,DAPK1,DNAL1,DGCR5,CEP170,POM121,SGSM2,DLG2,HS3ST4,SLC25A18,GNE,ARRDC4,DNM1L,PHC2,FCF1,KLHL5,CELSR3,FAM13A,SUGP2,EGFR,IRAK4,ELAVL4,USPL1,TUBD1,ETV1,TLR7,ADGRV1,TMEM132C,ZSCAN30,PPP1R1B,GTF2IRD2,KIAA1109,FHL1,POLK,CAP2,SEMA4D,PSD2,NOP56,WDR83,CAMKK2,ATP6V1H,CELF1,PNMA2,SDCBP2,ZNF44,GABRA5,GALNT15,DENND2A,GAD2,BRPF3,ARPP21,ZNF274,DISC1,GBX2,SULT1C4,MSTN,GGT5,CRCP,DBF4,GLYR1,GLS,LNX1,PSRC1,GPD1,GPD2,PRUNE2,GPR12,STON1,PLPP7,GRIN2D,NR3C1,GRM7,GSTT2,MFSD2A,GUCY1B1,FAM222A,UBE2QL1,FRMD5,LINC01102,AGBL5,NEGR1,IGFBP1,NKD1,IL11RA,INPP5B,ITGAM,SLC35G1,KCNB1,KCNJ16,KCNMA1,GATD1,KIF5C,LINC00634,IPO5,SFXN5,SYTL4,PIK3AP1,CLEC18A,MAN2A2,CHIC1,MDM4,MEIS2,KITLG,MN1,MOG,CD200,MPP2,ERICH3,PTOV1,MTR,MYO9A,CCDC13,NF1,NOVA1,SMIM11A,NTRK2,OCRL,OGG1,PAH,GLIPR1L2,PCDHGC3,PCSK5,PDE1A,PDE1C,PIRT,PDYN,NALCN,CCSER2,FTO,PLP1,ZNF426,PLXNB1,RC3H2,SDK2,PACSIN1,LRRN3,PPP3CB,PRKCB,PRKCG,GRAMD1C,DIRAS2,SYTL2,NCR3LG1,ZSCAN32,PTPRE,ZSCAN2,PLEKHB2,RALGDS,SLC25A41,NWD1,ROGDI,OXR1,RASGRF1,TRIM68,REV3L,ARHGEF10L,ZNF532,SUGCT,TMLHE,KLHDC8A,ARMC5,CARF,ROBO2,ELP2,UEVLD,KIAA0895L,SGSM1,LRRK2,PTGR2,KCNIP3,RTKN,RXRG,DGLUCY,MAPK12,SEMA6D,CSRNP3,DRAXIN,HOGA1,SCN2B,LRRTM4,SCNN1D,SCP2,TNFRSF19,GALNT10,SUPT20H,SH3GL3,AMBRA1,ZNF365,WDR47,FAM214B,KANSL3,PKNOX2,SLC6A11,YPEL4,RAB3GAP1,ARHGEF40,SLC14A1,SCMH1,BTBD7,CDK5RAP2,SMARCD3,MYH15,ANKRD36,RIMS1,SNCA,FAM219A,DOP1A,ZSWIM8,NMNAT2,EMC1,ARHGAP26,NFASC,PBLD,CLSTN2,STOX1,SYT11,ZC3H4,SYNE2,TAC1,KAZN,MTCL1,FAM208A,KLHL4,WSCD1,ACSL6,DMXL2,CUX2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,PCDHB3,PCDHA5,FRYL,RNF216P1,PMS2CL,TGFBR3,SLC44A1,THRA,TLL2,C5orf64,TPD52L2,TPM4,CHST5,RUNDC3B,TRO,TRPC3,TRPS1,PPIL6,TSN,ANO5,TTTY15,CADM1,RPL7L1,VIPR2,VLDLR,RICTOR,ZNF708,CFAP52,TCEAL7,DPYSL5,MEIS3,SLC30A4,CADM2,STMN4,SCG2,SIGLEC10,PCDH15,PCBP4,FAM13C,MARCH8,DPF3,SLC4A10,FAM198A" MicroRNA hsa-miR-642:mirSVR_lowEffct hsa-miR-642:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.09E-140 2.86E-136 8.40E-139 7.74E-138 415 1985 "TTYH1,ACADM,ASIC1,GALNT16,HHATL,BRAP,PNMA8B,SORCS1,ERMN,PWWP2A,KIAA1211,PTCHD1,NLGN4X,SLC24A4,KIAA1324,AK2,ZNF578,C1QTNF3,ALAD,CARNS1,FAM135A,ALK,PDZD4,BEGAIN,PITPNM2,ANK1,CCDC146,PPFIA1,ANXA7,CNTNAP1,APBB1,KCNAB2,GPAM,VAT1L,PPFIA3,CDK10,SEMA4G,ARRB2,CAPRIN2,DACT3,NUMB,ASTN1,INSYN2B,CCDC181,ATP2B2,SLC2A11,MTMR9,ADAM23,TTLL9,CARMIL3,BACH1,LINC00847,ZNF599,KSR1,ARHGEF7,LINC00906,BTK,GYG2,CA12,DDR1,PTBP2,CAMK2A,TRIM41,CBS,RGN,ARHGEF1,CDC42,DCLK1,LRRFIP1,L3MBTL4,MAGI1,TIGD7,CLGN,CIART,RCBTB2,CASC2,PLAA,KIAA1549L,NRXN2,NIPBL,PICK1,PCYT1B,FAM171B,PREPL,C2CD2,CRY2,ABCG1,SEC24C,ATRNL1,CHD5,NCAN,PDE4DIP,DZIP3,ERC2,PLCXD3,RIMS2,GPSM1,DCAF4,CX3CR1,NOS1AP,ARHGAP32,DCAF8,FRMPD4,PHF19,ZNF337,LIN54,PHYHIP,IST1,DAPK1,TOMM20,BRINP1,DNAL1,ARMCX4,MFAP3L,FBXL5,KIAA0753,RUSC2,C2CD2L,ZC3H11A,PLPPR4,SRGAP3,NTM,SGSM2,G3BP2,RABGAP1L,MTX3,DLG2,DLX1,DMD,DNM1,NYAP1,DNAH9,NR1D2,CASP8AP2,ATN1,RCAN1,GNE,DTNA,DYRK1A,EBF1,SEZ6L2,EDN1,HIPK3,SYT15,HEYL,TMTC1,CELSR3,MRO,ABI2,ING4,ELAVL4,C3orf18,EMX2,ENO2,ERBB4,ZNF549,SPEG,DUSP27,ANKMY1,RASL12,ADGRV1,CLVS1,FABP7,CACNG2,PTK2B,ZIC4,ZNF589,FGF1,AGAP3,FOXO3,PSD2,ZNF605,DACH2,GPR153,NSG1,KBTBD12,NRG3,FYB1,SDCBP2,MEGF11,CHL1,AHCYL1,BRPF3,B4GALNT1,RAPGEF6,ZNF274,SIGLEC8,LRRC37A6P,GCNT2,CYP46A1,PCDH17,HEPN1,GJB1,GNG3,GPD2,FUT10,PRLHR,PCLO,GRIA2,DIDO1,GRID1,SERP2,GRIN2C,GRM1,GRM7,BTN2A1,RNF165,AP4S1,GUCY1A1,WIF1,RASSF8,NXPH2,TNFAIP8L3,ARHGAP36,HLF,HNF4G,CPT1C,AGFG1,HSD17B1,FAM95B1,IDH3B,MYLK2,C2orf72,C5orf24,ITGAM,SLC35G1,CDH20,KCNH1,KIF5C,LINC00634,A1BG-AS1,KTN1,TTYH2,ASPRV1,MAN2A2,MAPT,LDLRAD3,AFDN,N6AMT1,SCG3,MTR,MYO7A,NAP1L1,FXYD6,NCAM1,NOVA1,SLC11A2,ODF2,OGDH,ZDHHC22,PAK3,PDE1C,PDE3A,PDE3B,PIRT,PFKFB4,OLA1,SERPINE2,SEMA5B,ZNF655,HMGCLL1,LRP12,EXOSC10,PRRX1,FAT3,SH3KBP1,MED1,PRKCB,FITM2,MASP1,CNNM2,BCAS3,WBP1L,PTK2,PXK,PTPRE,PTPRH,PTPRO,RAB5B,PID1,FAT4,RAP1GAP,ZCWPW1,RASGRF1,RFX5,ARHGEF10L,ZFHX4,LGI2,ALG9,PNMA8A,ROBO1,KIRREL1,SNX22,EPHA10,BAALC,KIAA0895L,GLDN,SGSM1,PRR5L,MEG3,HUNK,ATAT1,KCNIP2,AMER2,FOXRED2,ATXN7,SCN2A,SOX6,CASC3,FOXRED1,ASRGL1,ITSN1,SH3GL2,MYO18A,MAGI3,AMBRA1,ABLIM3,SLA,SMTN,FAM214B,KANSL3,LRRC55,SIRT2,CDK5RAP3,SLC9A5,SLC14A1,MYH15,RCOR3,SNCB,LMBRD1,UNC80,FAM219A,DOP1A,PDZD2,TNIK,BDP1,FNBP1,ENKUR,IDI2-AS1,PEG10,KIF1B,NPAS3,NFASC,CLSTN2,SMOC1,SSTR2,LRRC4,NCDN,SEPT3,FAM168A,SYT11,ABCC8,SYT1,DDHD2,TAL1,TBCEL,TBX15,WSCD1,TPCN2,SZT2,NAT16,DOCK9,PHF24,TMEM151B,FRYL,AHCYL2,CHST8,SPX,AKTIP,GZF1,TMEM9,TLR4,LRRC8A,KCTD2,PIK3R5,ZNF384,SMUG1,RUNDC3B,AMACR,STXBP4,TRPS1,ZMYND8,ANKRD20A2,ANO5,UBE3A,AMOT,PITPNB,FLRT1,BEST1,WIPF1,LAT2,RICTOR,ZNF711,ZNF708,GPR158-AS1,MKRN3,LYPD6,CELF4,PCBP1-AS1,TFIP11,MEIS3,UPF3A,DHX33,SLC30A3,PRTFDC1,GDPD5,ADAMTS9,FIP1L1,PARP11,PDSS2,PAK5,KAT6A,CAMK1G,VANGL2,FRMD6" MicroRNA hsa-miR-145:mirSVR_highEffct hsa-miR-145:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.08E-140 5.10E-136 1.49E-138 1.38E-137 346 1396 "RALGAPA1,CLK4,NCKAP5,NBAT1,SLC25A25,CSMD3,FMNL2,CCDC85A,TMCC3,ADD3,SORCS1,ERMN,PTCHD1,SLC24A4,MTUS1,HECW2,RTL9,OSBPL1A,SEMA6A,SPOP,FAM135A,AMPD3,LCORL,PKP4,APAF1,EPB41L5,UPRT,GPAM,ALS2,CACHD1,SHTN1,LGR5,SEMA4G,PPP4R4,ARNTL,ZBTB10,ATM,ATP2B1,BARD1,NRP2,CFLAR,DST,SYNJ1,C5,IL33,CACNA1D,CACNB2,THSD7A,CAMK2D,CAST,MTMR7,CDH2,MAGI1,CFL2,JAM2,LHX2,ZFYVE9,FAM189A2,TJP2,CNN3,BTF3L4,SLC4A7,SLC4A8,TBPL1,BAG4,ZFP28,CHD1L,ZNF385A,CPS1,CRHBP,HAPLN1,ANKRD44,SIPA1L1,VAC14-AS1,PDE4DIP,PLXNA4,APPL1,UBXN2A,PHF14,EDRF1,KATNAL2,RIPOR2,ARHGAP24,KCTD8,TMEM170A,BRINP1,SIRPA,ARMCX4,YTHDC1,DNAJC6,ZEB2,MAGI2,BLOC1S6,ZC3H11A,DDX46,WDR20,DLG4,EXOG,HS3ST4,NR1D2,PDCD6IP,RCAN1,ARRDC4,DTNA,DYRK1A,EBF1,ATL1,FCF1,EFNA3,PHF20L1,EGFR,KMT5B,ELAVL2,C3orf18,DCTN4,GPHN,VPS26C,ADGRV1,FAM198B,ACSL4,EFEMP1,ZNF589,GORAB,GTF2IRD2,KIAA1109,SPSB4,FGF14,FGFR3,RGPD5,FLT1,SGIP1,TMEM107,UFM1,ST6GALNAC3,MEGF10,HRASLS5,GABRA5,GABRB1,ARPP21,GALR1,DISC1,LRRC37A6P,IGSF5,MSTN,WASHC2A,ADAM28,GGTA1P,GGT7,LYVE1,PCDH11X,STARD3,KDM2B,HTATSF1,OS9,LUZP2,KCNMB4,GPD2,PRUNE2,ATP2B1-AS1,GRB10,GRIA4,GRIK2,FAM19A2,TMEM25,PSIP1,MIER3,GABARAPL2,ZDHHC15,ZNF181,ZNF546,DOCK7,SCIN,ZNF678,SLC35G1,METTL21A,KCNA4,KCNC1,KCNK1,KCNMA1,CYP27C1,LAMP2,VWA5A,HECTD2,NCOA7,MARK1,MAT2A,MEIS1,SRSF12,MEST,MID1,PPM1L,MMP16,COMMD5,MSRA,N6AMT1,NAP1L1,NCAM1,OTOGL,CNOT4,NRCAM,SMIM11A,GPR137C,PDE3B,FAM218A,SNX10,XRN1,FAM216A,JAKMIP1,PLP1,HMGCLL1,PDZRN4,PSAT1,EXOSC10,RETREG2,PPARA,TATDN3,PPP3CA,MAPK4,MAPK9,PRPSAP2,BDNF-AS,TMEM260,EML5,ZSCAN2,TTC13,ZNF615,TMEM255A,SH3TC2,DBX2,RADX,BSDC1,TRIM68,REV3L,RFX4,UBR7,RGS7,SLC25A36,ZFHX4,GSTCD,TMEM206,RPE,RPE65,NEK11,ATP8B4,PTGR2,RPS20,RTKN,CLIP1,NCBP3,ZNF331,AP1AR,ATXN2,SCN2A,ZFP2,COPZ1,KIF21A,NTNG1,FNDC3A,R3HDM2,NLGN1,FAM81A,RUFY2,SLC6A1,SLC8A3,CPEB4,SLN,TTC17,RIMS1,SNAP25,FAM126B,USP33,SON,ENKUR,IDI2-AS1,ZNF423,CLASP2,CLSTN2,POGZ,ZNF302,ZC4H2,SS18,ERBIN,ELOVL4,RGL1,PRRC2C,SYT1,ANKRD28,SYT4,C12orf76,ATP11A,MTCL1,MCF2L,TAF9,CAMSAP2,DMXL2,SATB2,WDR7,SYNE1,DOCK9,SLC19A3,OBSL1,TF,FAM200B,ZNF106,ENHO,MTMR14,HEY1,TJP1,TLR4,CSMD1,TP53BP1,TPM1,TPM3,C9orf85,TPM4,SMUG1,PPIL6,RPL7L1,UGT8,PLEKHH2,USP1,BEST1,TBC1D15,WIPF1,CFAP298,PCDH20,ZIC3,ZNF711,ZNF708,KCNT2,ZNF138,UPF3A,PRDM2,RNF103,TMEM178A,NAV3,NAV2,SNX27,FIP1L1,GOPC,UBE3B,PAK5,CASC15,RNF170,NETO1,SLC4A10" MicroRNA hsa-miR-1256:mirSVR_lowEffct hsa-miR-1256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.10E-140 5.11E-136 1.49E-138 1.38E-137 359 1502 "RALGAPA1,TTYH1,ASPHD1,NBAT1,SLC25A25,KLHL32,GRAMD1B,PTCHD1,BEND6,SLC24A4,ZNF608,OSBPL1A,CC2D2A,C1QTNF3,ALCAM,ABCD2,ARHGAP20,BBOX1,UNC79,TRMT9B,AMPD2,OGT,SEMA7A,SUGT1P4-STRA6LP-CCDC180,PKP4,CNTNAP1,APC,ALS2,VAT1L,SHROOM2,MIER1,IGDCC4,PDE8B,ASPH,EIF4G3,ATP2A2,B3GALT2,BACH1,BCHE,BCL7A,CFLAR,DST,SYNJ1,SYNJ2,ARHGEF7,FUBP1,THSD7A,SLC25A14,VXN,SPAG9,RUNX1T1,CBLN1,P2RX6,ENTPD6,DGKI,LGI1,MAGI1,TIGD7,COPB2,CHM,KIAA1549L,FAM189A2,HECTD1,CNTFR,CNTN1,ARMC8,FAM149A,SLC4A8,IFFO1,SMARCAL1,CLOCK,CREB5,AKAP12,GDA,SEC24C,FEZ2,ATRNL1,PDE4DIP,PLCXD3,GREB1,CTNND2,ECE2,FRMPD4,HDAC4,TM9SF4,TBC1D5,TMEM170A,PABPC5,C8orf34,MYEF2,SPOCK3,SRGAP3,NTM,WDR20,RAB39B,DMD,NYAP1,DYNC1I1,CDON,DNM2,RCAN1,MAMLD1,DNAJB6,AASDH,EBF1,EDNRB,FCF1,CNNM1,SEMA3D,EGR3,KCTD3,EIF4G2,PCOLCE2,EML1,EIF1,EPB41L2,RCAN2,LRRC17,SRRM1,EPS8,ERBB2,ZNF549,CDHR1,TLR7,CEND1,EYA1,ACSL4,TAOK3,SCML2,ATP8A1,CHST15,ZSCAN30,GORAB,FGF1,FGFR1,SUCO,HPCAL4,SYNCRIP,FLT1,ANKFY1,C2orf88,SORBS1,ZBED3,NPTN,NSG2,GABRB1,SALL3,DISC1,LRRC37A6P,SULT1C4,MSTN,FREM1,GGTA1P,PPARGC1A,GLRB,MSL3,HTATSF1,LUZP2,DCLK2,RAB40B,WDFY3-AS2,CNTRL,RAPGEF4,GRIA2,GRIA4,ADAMTS13,GRM1,GRM2,PRDM5,TMEM25,ZBTB49,BVES,AP4S1,WIF1,HAS2,UBE2QL1,ATXN2L,LINC01102,VSIG4,HNMT,SHISA6,SMAP1,EID2B,LINC00667,TJAP1,IL6ST,INSM1,JAK2,KCNA4,KCNJ3,KCNK3,KCNMA1,IPO5,STXBP5,STMN1,PAXBP1,LMO2,ZFYVE27,MAT2A,MBNL1,MMP16,MOBP,CPNE9,CCDC80,RTL5,NEXMIF,P2RY13,NCAM1,ZC3H12B,NEK1,NEUROD1,NF1,NOS1,CNOT4,DNHD1,SMIM11A,GPR88,GLIPR1L2,ETFRF1,PCSK1,PRTG,PDE4D,ENPP2,SLC10A4,GNG2,SEMA5B,SLC25A23,PCDH18,HMGCLL1,PNMA3,MAPKAP1,STRN3,MBOAT7,FAT3,CRLS1,PPP3CA,PKIA,PRKCB,EPDR1,LRRC49,PIGG,CNTLN,PTPN13,PTPRN2,NKAIN1,PID1,SLC25A48,HKR1,KHDRBS2,ZDHHC14,TRIM68,FIGN,RGS12,SLC25A36,RIC8B,TMLHE,ACER3,MEG3,RXRA,AMER2,MIR124-2HG,SEMA6D,SCN2A,HES6,TRA2B,PPM1E,FBXO11,FHOD3,NLGN1,SLA,RPH3A,PREX2,PPP4R3A,EPN2,LRRC55,SLC14A1,BTBD7,SLC20A2,SPHKAP,ANKRD36,MBD5,KIF13A,PALLD,KDM4B,SON,PDZD2,WDTC1,SOX10,GLT8D1,CAND2,HECW1,KDM4C,TEX2,LHPP,PBLD,ITPRID2,MAPK8IP3,STAU1,RGL1,DIP2A,SULF2,FGD4,PRRC2C,TMEM150C,PDLIM2,AGTPBP1,KLHL4,SATB2,TCF12,WASHC4,RALYL,PCDHB4,FRYL,CYB561A3,RNF216P1,ZFPM2,CRB1,MTMR14,TMOD1,TNFRSF1B,R3HDM1,CSMD1,TNS1,ZNF384,TUB,CADM1,SLC35A4,SLAIN1,PITPNB,OSBP2,FLRT2,VLDLR,BEST1,WIPF1,NSD2,CLDND1,ZBTB14,ZNF23,FMN2,ZNF154,TMEM237,FSTL5,PLPPR5,SMARCAD1,MEIS3,INTS3,CA10,PRDM2,STOX2,TMEM178A,PCDH15,GAL3ST3,TMEM163,ST7,HNRNPA3,CASC15,JMJD1C,SLC4A10,LAS1L" MicroRNA hsa-miR-27b:mirSVR_highEffct hsa-miR-27b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.10E-139 6.16E-136 1.80E-138 1.65E-137 363 1536 "RALGAPA1,NCKAP5,SLITRK1,CCDC85A,ADD3,GRAMD1B,ADORA1,KIAA1211,ADORA3,PTCHD1,OLMALINC,ZNF608,INTS2,HACE1,WDR35,TAOK1,SEMA6A,ALCAM,ANK2,ANK3,SEMA7A,PKP4,APBA2,GPAM,DDO,VAT1L,ASPH,NCOA1,ATP1A2,STX16,ATP2B1,ZNF582,RNF182,NOL4,RIPK1,TTC9B,NRP2,BLM,PROM1,CDK5R1,C5,CACNA1A,CACNB2,CABP7,CAMK2D,VSTM2A,MTMR7,INA,SCARB1,C1orf52,ZMYM4,MAGI1,CIART,CFL2,ADGRG1,SRSF11,CASC2,MS4A7,KMT2C,CLCN3,NRXN1,QKI,NIPBL,CNN3,ARHGEF6,AKAP7,ARMC8,LETMD1,SLC4A7,ZFP28,CHD1L,ZNF385A,SLC35F1,PNKD,CRMP1,HAPLN1,GDA,SEC24C,LRRC3B,SUSD5,VCAN,EDRF1,HDAC9,RIPOR2,DCAF8,TOX,LONRF1,KCTD8,DGKB,TMEM170A,PABPC5,DNAJC6,C8orf34,POM121,SNAP91,CHRDL1,GRIN3A,NR1D2,RCAN1,ARRDC4,DTNA,DNM1L,E2F5,EBF1,FAM135B,EDNRA,TMTC1,FAM13A,EGFR,MBNL2,LPAR6,ASB3,EIF5,ELAVL2,RGS17,CALCRL,EN2,EPB41,RCAN2,EYA1,EZH1,HSPA12B,TOMM40L,TESK2,KIAA1109,FGF1,FGF12,FGF13,FGF14,SUCO,CAP2,RGPD5,ARFGAP2,DACH2,ST6GALNAC3,NSG1,AP4B1,BRSK1,OGA,NEURL4,GABRB3,CAB39,BRPF3,NEK6,NCKAP1,IQGAP2,ERAP1,DISC1,NEU3,ARFIP1,PPARGC1A,GK,GLI2,GLYR1,GLS,TOX3,ZNF638,ADGRA3,GPD2,GPM6A,GPR37,GRIA4,NR3C1,GRM5,RNF165,RNFT2,FAM222A,MAEL,ZHX1,MIER3,CFAP126,HSPA1L,MSL1,ZNF181,SOWAHA,ZIC5,ZNF678,INPP1,NME9,KCNJ16,KCNK2,CREG2,KLRC2,STXBP5,PAXBP1,HECTD2,ARHGAP12,NCOA7,C2orf80,SMAD1,SMAD9,MARK1,LYPLAL1,MAT2A,AQP11,MATN3,MBD1,SYT9,MEIS2,KITLG,MOBP,ERICH3,ZNF680,MRPL42,MXI1,NAP1L2,P2RY13,NCAM1,NEK1,NF1,OTOGL,NFE2L2,CNOT4,NOVA1,NPPA,PCDH9,PDE3A,PDGFRA,PRIMPOL,RC3H2,LRP12,SEPT4,POU3F2,PPM1B,PPP3CA,CEP41,PKIA,PRKCB,PKN2,MAPK9,GRAMD1C,HYDIN,DCHS2,RELN,DEF8,PIGG,CNTLN,PTAFR,PLPPR1,MTMR10,ZSCAN32,QDPR,SH3TC2,FAT4,FAM184A,ENOX1,ZNF493,ARID4A,KHDRBS2,RET,REV3L,ERI2,RFX3,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,TMLHE,RORB,ELP2,FBXW7,ATP8B4,MEG3,NCBP3,TRAPPC13,TRIM46,ARX,CPEB3,SHC4,HKDC1,MAGI3,CHD9,PAAF1,SLA,EPN2,SLC6A1,SLC8A1,KBTBD4,ZNF334,TET1,CPEB4,RCOR3,SNAP25,SNRPN,TMCC1,TNIK,BDP1,KDM3A,KDM4C,PEG10,KIF1B,TROVE2,COLGALT2,STOX1,ZNF302,SSTR1,LARP4,ERBIN,NXT2,SEPT8,TTBK2,NECAB1,ARHGEF9,VPS13A,TACC1,DDHD2,CAMTA1,TAF9,PDLIM2,TCEA1,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,RALYL,USP32P1,FRYL,SIK3,TF,FAM200B,CRB1,TGFBR3,THRA,ACTR6,CSMD1,TPM1,NPL,ZNF384,SYNPO2,PRMT8,TSC1,TTC3,TUBB2A,CLHC1,CADM1,GORASP1,DNAJC12,PLEKHH2,ZNF709,BEST1,ZNF781,SLC13A3,XPO1,ZNF708,ZNF540,GPR158-AS1,MKRN3,FSTL5,ZSCAN26,SMARCAD1,DHX33,CA10,LRP8,TMEM178A,CAB39L,DOCK8,JMJD1C,VANGL2,ADAMTS10,NETO1,SLC4A10" MicroRNA hsa-miR-3156:mirSVR_lowEffct hsa-miR-3156:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-139 6.84E-136 1.99E-138 1.83E-137 374 1629 "SDE2,ADAR,FMNL2,KLHL32,TMCC3,CDC7,ADORA2A,ESYT2,DPY19L2P4,SLC24A4,AP1B1,INTS2,KCTD16,WDR35,AK2,ZNF578,HFM1,AMPD2,ZFAT,OGT,ANK2,MAP4K3,PPFIA1,PKP4,CNTNAP1,GPAM,ALS2,PHYHD1,PPFIA3,AQP6,TMEM263,TMEFF1,ARHGAP5,CDK13,CCDC74A,CAPRIN2,NUMB,ATM,ATP6V1G2,MPDZ,BID,PROM1,KSR1,SGCE,RAB29,BTRC,CACNB4,PTBP2,VSTM2A,CBR1,CD86,C1orf52,ZBED1,CDR1,CCPG1,DIS3L,ASIC3,MS4A7,B4GALT6,KIAA1549L,COG1,CLU,SRP14-AS1,NIPBL,IGLON5,ARHGEF6,IQCK,ARMC8,AKAP6,BTF3L4,RCHY1,GDA,CS,RGS6,CSNK1G3,PDE4DIP,DZIP3,PPP1R16B,GREB1,CFAP61,PUM1,DCAF4,EDRF1,NOS1AP,KIAA0408,ARHGAP24,DCAF8,MAML1,DAPK1,IP6K1,FBXL5,KLHL3,BLOC1S6,SPOCK3,NTM,WDR20,FAM107B,KBTBD11,CPEB2,SLC12A6,DSCAM,E2F5,AASDH,SNX29,EDN1,ANKRD46,HEYL,KLHL5,TMTC1,RBM12,SUGP2,ELAVL4,C3orf18,CALCRL,USPL1,VPS13B,GPHN,RABEPK,RTN3,DNAJC27,KATNAL1,ADGRV1,RPS6KC1,ACSL4,ZIC4,TAOK3,MED12L,POLR1B,FGF11,UBE2E3,IP6K2,EVL,ANKFY1,SLC37A3,SORBS1,TMEM107,SMC2,UFM1,TPK1,ST6GALNAC3,STAU2,B3GAT1,GAB1,GABRA2,GABRA5,GABRB3,GAD1,ERAP1,ZNF559,SEPT9,ATP8A2,WASF3,NEU3,GCNT2,GHR,TCERG1,MSL3,ZNF638,KDM2B,GPM6B,GRB10,GRIA2,ADAMTS8,GRM5,ZNF496,LINC01089,GSTM5,NXPH3,ARHGAP36,MIER3,HMGB1,SYNPO,HNMT,MYLK2,IGF1,SCIN,IL6ST,SCRT2,INPP5B,KCNJ9,KCNJ10,KCNMA1,CREG2,KIF5C,INSYN2,MARK1,MAT2A,MDM4,MEF2C,AFF1,XRRA1,MMP16,MOG,SAMD5,MSR1,PTOV1,N6AMT1,RSPO2,RTL5,NAP1L1,NASP,NDUFA5,NEUROD1,NF1,NHLH1,NOVA1,OCRL,OGDH,OPCML,OXTR,PCDH9,PCSK1,PDE1A,PDE1B,ZNF655,SNX10,SLC25A23,PURG,PPM1B,TATDN3,PPP2R2C,DIRAS2,DCHS2,ELOVL2,PTPRE,PTPRH,PTPRO,FAM120C,C1orf109,PTPRZ1,FAM66C,SH3TC2,SUSD4,RBBP6,RADX,VEPH1,ZDHHC14,ZYG11B,RFX4,UBR7,RGS12,PRIMA1,TTLL7,KIF7,SEC61A2,RIC8B,ELP2,CCDC102B,ZC3H14,MEG3,ATAT1,KCNIP2,CLIP1,SALL1,MIR124-2HG,ATXN2,SCP2,SEC14L1,TRIM46,SFPQ,ASRGL1,KIF21A,MYO18A,MAGI3,FNDC3A,CTXN2,SLA,SLC1A3,RPH3A,SLC2A5,PPP4R3A,EPN2,LRRC55,SLC6A7,SLC6A11,SEPHS1,SLC8A1,RAB3GAP1,SLC8A3,TRIM67,NAPB,ELMO2,SLCO1A2,SMARCE1,IFT122,ANKRD36,SNCB,MBD5,SNRPN,UNC80,TRERF1,SOX11,ZSWIM8,SP4,ENKUR,GLT8D1,ERC1,RBM26,DDN,NFASC,LHPP,C11orf87,POGZ,ITPRID2,NCDN,STAU1,CEP68,TTBK2,NSFL1C,KLHL7,SYT11,JMJD6,VPS13A,NUDT10,SYP,SYT4,ATP11A,DNMBP,UNC5D,TBCEL,TMEM136,VWC2,SATB2,ZEB1,WDR7,RALYL,PCDHB4,AKNA,PUM2,TNS2,FRYL,AHCYL2,DICER1-AS1,ZFPM2,CRB1,C18orf54,ZNF106,ACTR6,KCTD2,TP53BP1,RBFOX2,RGMB,TRIO,RUNDC3B,TRPS1,DCBLD1,RUSC1,CADM1,LINC00689,FLRT2,NSD2,XRCC4,ZNF708,ZNF28,TRIM9,ZNF74,FSTL5,PMEPA1,EMSY,DNALI1,EVI5,NAV2,TMEM163,PARP11,DNAH10,PHTF2,RSPRY1,RNF170,SNX14,SLC39A12,FRMD6,IFT88,SOCS4,GAN" MicroRNA hsa-miR-26a-2*:mirSVR_highEffct hsa-miR-26a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.34E-139 7.54E-136 2.19E-138 2.01E-137 360 1512 "CPNE2,ACADM,NCKAP5,NBAT1,ACTN2,KDM5D,XKR4,FMNL2,SLITRK1,ADD3,BRAP,SORCS1,PLEKHH1,GRAMD1B,KIAA1211,ADRA1D,OSBPL1A,CC2D2A,TAOK1,ADGRF5,C1QTNF3,LRRC7,ALCAM,PCDH10,FAM135A,ALK,OGT,DPP10,LRCH2,CCDC146,USP28,TNRC6C,CASK,TMEFF1,ARNTL,ASPH,ZBTB10,DDX3Y,DYNLL1,ATM,ATP1A1,SLC4A4,ATP2B1,ATP2B3,RNF182,ADGRB3,BBS2,BID,CFLAR,DST,SYNJ1,RAB29,CA8,CACNA1D,CACNA1E,CALM1,KALRN,CAMK2D,CANX,KRIT1,INA,C1orf52,LRBA,ZMYM4,B4GALT6,ABCG2,QKI,ARMC8,TBPL1,AHCTF1,ZFP28,CHD1L,SLC35F1,CREM,RBM39,ARHGEF10,ATRNL1,PDE4DIP,DZIP3,ERC2,PHF14,GREB1,CTNND1,CTNND2,RIMS2,USP6NL,TCAF1,DCAF8,MATR3,KCTD8,DAPK1,PABPC5,BRINP1,DCC,C8orf34,ZEB2,MFAP3L,FBXL5,BLOC1S6,DDX46,KBTBD11,CHRDL1,DLG2,EXOG,GRIN3A,RAB39B,DMD,NR1D2,DMTF1,DPP6,DPYSL2,ECM2,ABCC5,DNM1L,GOLT1B,WDPCP,ANKRD46,RASGRP1,OPTN,PHF20L1,SUGP2,AASS,PLEKHA1,ING4,C8orf37,CALCRL,EPB41L1,KCNMB2,RABEPK,RTN3,TLR7,EXTL1,ADGRV1,CLVS1,FAM198B,ACSL4,SCML2,ATP8A1,CEP78,FCGR3A,FER,MED12L,CAP2,SYNCRIP,ERGIC3,ST6GALNAC3,GABRA5,GABRG2,TRAF3IP2,FAM120B,ZMYND11,DISC1,GCNT2,SULT1C4,WASHC2A,MALT1,LYVE1,TXNL4A,TCERG1,HPGDS,GLYR1,GLUL,PCDH11X,ZNF638,ZNF782,PRLHR,NUDT21,GRIA4,GRIN2C,GRM7,FAM19A2,RNF165,ADAMTS6,RASSF8,NXPH2,HSP90AA1,EID2B,SOWAHA,DOCK7,USP54,IL12A,ZNF678,SLC35G1,KCNB1,KCND2,KCNJ3,KLRC2,LMO2,LSAMP,LOC100128239,MAOB,MARK1,SYT9,MDM4,MEIS1,SRSF12,MRPL42,NRBP2,SCG3,NAP1L1,NAP1L2,NCAM1,NEK1,NELL2,NF1,SLC11A2,NRCAM,HCN1,IGSF11,OCRL,CHAMP1,OLR1,OPHN1,SNTG1,CNTN3,PCDH9,PCMT1,PCSK5,PDE4D,BEST3,PFKFB2,OLA1,GDAP1L1,PIK3C2A,FAM218A,FAM216A,PLP1,HMGCLL1,PRIMPOL,PRRX1,SLC36A4,SH3KBP1,MINDY2,TATDN3,RANBP3L,MAPK9,HYDIN,DIRAS2,DCHS2,SAMD9,SNRK,PIGG,ANKHD1,BDNF-AS,TMEM260,OCIAD1,PTPRG,USP47,FAM66C,SH3TC2,ENOX1,KHDRBS2,SLC6A15,CRTAC1,ZYG11B,ERI2,RGS4,RGS12,RIC8B,RPRD1A,GSTCD,ROBO2,CCDC102B,ATP8B4,MEG3,ZNF568,ZNF331,SCN2A,SCN3A,SLC30A10,SCAF8,ITSN1,NTNG1,MAGI3,FBXO11,CTXN2,SLC1A3,SLC8A1,EFHD1,SLC20A2,CPEB4,ZNF667,SMARCE1,ANKRD36,SNCA,SNRPN,UNC80,MYT1L,SP4,CLUAP1,CAND2,PEG10,RBM26,LMO3,SRPK2,ATP10B,CLASP2,TROVE2,SSTR2,NKAIN2,NXT2,DIP2A,SULF2,KLHL7,PRRC2C,SYNE2,VPS13A,TMEM150C,SYT1,COBL,TACR1,DNMBP,CAMSAP2,KIAA1107,TBX15,WSCD1,SATB2,ZEB1,TRIM2,DOCK9,SLC19A3,PCDHB7,PCDHB3,NSD1,GPRIN3,FRYL,TEX15,SIRT1,ZFPM2,DAAM2,TNS1,TPD52,CDK20,RGMB,SYNPO2,METTL3,TRIO,ANO5,ZNF610,UBE2H,FLRT1,CCDC14,WIPF1,XPO1,ZBTB14,KCNT2,TMEM237,FSTL5,ZNF184,EML6,ANKS1B,PLPPR5,UPF3A,SLC30A4,PCDH15,EPM2A,JMJD1C,FXR1,NETO1,SLC4A10" MicroRNA hsa-miR-29b:mirSVR_lowEffct hsa-miR-29b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-139 8.16E-136 2.36E-138 2.17E-137 389 1759 "VWA5B2,ABCF1,ACADM,CLK4,NDRG2,FMNL2,ADCY2,SLITRK1,ADD2,BRAP,SORCS1,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,LRRC7,CARNS1,ZFAT,CDC42BPA,LRCH2,ANK3,FGD2,CCDC146,GAS7,DGKZ,DGKD,PHYHD1,TNRC6C,USP37,SHROOM2,CDC14B,CDK10,ARHGAP5,ARHGDIG,ARSF,LINC00173,MARK4,ZBTB10,DDX3Y,ATM,DOCK11,ADAM15,MIR9-3HG,BMPR1B,SYNJ2,MTMR2,JAZF1,BSN,LDLRAD4,CA4,CACNA1A,CACNA1E,CALM1,KALRN,CAMK2G,CANX,BRSK2,CARS,ARHGEF25,CD81,CDC42,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,CASC2,SYNPR,B4GALT6,CHRNB2,CNOT8,EPS15L1,KIAA1549L,NMT2,CLTC,FBXO7,QKI,SULT4A1,NIPBL,WHRN,BTF3L4,AKAP5,IFFO1,MFSD4A,NCOR2,MICAL2,CSNK1E,ATRNL1,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,CTNND1,NRSN1,DCAF4,FAM131B,CYBB,HDAC9,KATNAL2,RIPOR2,HDAC4,TOMM20,IP6K1,BRINP1,SIRPA,ARMCX4,SPATA2,ELMSAN1,ZBTB24,HEPH,DDX46,ALKBH8,PLPPR4,WDR20,DLG2,CDON,FAM57B,DPYSL2,ABI1,ARRDC4,ECM2,ANKRD46,SGK2,SEMA3D,SIDT2,EFNB3,LPAR6,GOLGA7,KCTD3,PLEKHA1,C8orf37,EPB41L1,MTSS1L,SEZ6,ENPP6,ERCC2,NCALD,IGSF6,SPEG,MRPL37,CLVS1,WAC,POLR1B,FGFR1,HPCAL4,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,ZCCHC17,SMC2,TRIM16,STAU2,KBTBD12,MSANTD4,ABLIM2,MEGF10,GABRG1,GAP43,ERAP1,SRCAP,PCDH17,PPARGC1A,TCERG1,DBF4,GLI2,PCDH11X,STARD3,POLL,GNAS,GP1BB,DIPK1C,PRLHR,GPR12,CCDC184,CECR2,ATP2B1-AS1,GRB10,GRIA2,C1QL4,GRIA4,GRIK2,ADAMTS13,NR3C1,GRM1,GRM5,KIF3A,RNF165,GSTM5,BVES,WIF1,MUM1,RASSF8,ARHGAP19,TNFAIP8L3,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,INPP5B,TUBB2B,ZNF385B,ITGAM,ITPKB,KCNC2,KCNJ16,KIF5C,TTYH2,LAMP2,LIFR,VWA5A,MAT2A,AQP11,SCAMP5,MKLN1,MOG,ERICH3,COL28A1,COMMD5,MTR,RTL5,FXYD6,NEFM,NFIA,NFE2L2,NFIX,NPPA,HCN1,OXTR,P2RY1,KCNK10,PALM,PAX6,PCMT1,CDK18,PDE3B,SSH1,PIK3R1,ZNF655,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,GDPD1,WBP1L,SIDT1,PIGG,UHRF1BP1,EML5,FAM120C,PEX5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RBBP6,RDX,ZYG11B,TRIM68,RET,ERI2,GTDC1,RGS3,RIC8B,ZFHX4,SETD5,CARF,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,PAQR6,ABCA11P,KCNIP2,RTN1,STX1B,FAM182A,HOGA1,SMPD3,CASC3,GALNT10,KIF21A,PPM1E,FRMPD1,DOCK10,FNDC3A,ST6GAL1,ZNF365,RPH3A,PKNOX2,SLC6A8,SEPHS1,SLC20A2,LGI3,NAXD,SORCS3,TTC17,MAPKBP1,MBD5,SNRPN,SCN3B,DOP1A,SON,ZCCHC24,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,C11orf87,ZNF302,ERBIN,CEP68,STX1A,NSFL1C,ZC3H4,SUPT5H,ZFR2,ADAMTS17,SYN2,C12orf76,ATP11A,TACC1,CAMSAP2,VWA3A,SIN3B,NEU4,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZFP91,DAAM2,C5orf64,LILRA4,ZNF346,SYNPO2,ELP5,AMACR,ZMYND8,TUBB1,CLEC2L,AMOT,UBTF,PITPNB,PLEKHH2,NSD2,ZNF24,FMN2,SLC26A10,ZBTB38,ZFAND5,CADM2,CSDE1,XKR7,HPS4,PCDH15,GAL3ST3,TRIM16L,PARP11,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-24:mirSVR_lowEffct hsa-miR-24:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-139 8.62E-136 2.48E-138 2.29E-137 416 2000 "CPNE2,RALGAPA1,ACHE,TMEM132B,ADD2,PNMA8B,SORCS1,ADORA1,SNX30,LRFN2,BEND6,OSBPL1A,TXNDC16,SRPX,CEP126,ARHGAP20,FAM135A,SYT13,MRTFA,DPP10,ANK3,SEMA7A,FGD2,PPFIA4,APBB2,ALS2,CACHD1,SHROOM2,SEMA4G,ARHGDIG,MARK4,ASPH,NCOA1,RASL11B,STX16,CADM3,RIPK1,TTLL9,ADAM15,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,BMPR1B,LINC00906,BTK,CASTOR3,RAB29,WASF1,MYRF,DDR1,LURAP1,CABP7,KALRN,PTBP2,CAMK2D,CAMK2G,CAPN3,SYT6,CH25H,HIP1R,MAP7,PRC1,ZNF501,CBS,CCKBR,INA,P2RX6,CD86,CBFA2T2,SCARB1,ENTPD6,C1orf52,DGKI,CDK11B,ZBED1,CDH8,LARGE1,CRLF1,SRSF11,B4GALT6,CNOT8,TAOK2,LHX2,CLCN3,KIAA1549L,NRXN1,COG1,CLU,TPP1,CLTC,FBXO7,TJP2,CNTFR,WHRN,COL9A1,COL11A2,MAGED1,IFFO1,SMARCAL1,CHD1L,AKAP12,HINFP,RGS6,PLCH2,GALNT9,CTH,GPSM1,DCAF4,RUBCN,CX3CR1,ARHGAP32,RASSF2,DAPK1,GIT2,COPS7A,C2CD2L,ZC3H11A,DDX46,GUCD1,SV2B,SPOCK3,SV2A,RABGAP1L,DLG2,EXOG,GRIN3A,SLC29A4,CDON,DMTF1,SLC12A6,PDCD6IP,USH1C,EFNA3,APH1A,MRO,RASA4,SORBS3,COPS4,TNK2,C3orf18,EIF1,MFSD10,SEZ6,ENPP6,ANKRD13B,NCALD,SPEG,MRPL37,ETV1,VPS26C,ANKMY1,EZH1,FCGRT,ZSCAN30,PPP1R1B,ZNF589,AMOTL2,POLK,MEX3B,IP6K2,AGAP3,SLC37A3,DPYSL4,SORBS1,RASL10A,B3GAT1,ADGRA1,ABLIM2,GABRA1,HRASLS5,GALNT15,GAD1,AHCYL1,BRPF3,B4GALNT1,ARPP21,TMEM8B,DISC1,CYP46A1,GGT5,LYVE1,BRD8,TCERG1,SPIN1,PCDH11X,GOLGB1,GPD2,FUT10,MCHR1,NUDT21,TMEM121B,CECR2,GRIA1,GRIA2,DIDO1,GRIN1,GRM8,BTN2A1,LINC00839,RNF165,GSTM5,BVES,ADAMTS6,WIF1,GABARAPL2,HMGCL,DHX35,LRRC75A,ATCAY,IDH3A,C2orf72,KNDC1,IL12A,DIPK1A,KCNA4,KCNN2,KIFC3,A1BG-AS1,KLC1,STMN1,FGFBP3,PIK3AP1,LOC100128239,ZFYVE27,MAP2,MAP4,CHIC1,MEIS1,SCAMP5,PPM1L,AFDN,MMP16,MN1,GIT1,DBNL,JAKMIP3,N6AMT1,MYO9A,NAP1L1,P2RY13,NBL1,NFE2L2,NOS1,NPTX1,SLC11A2,OGDH,OPCML,PCDH9,CDK18,PDE1A,PDE2A,PFKFB3,TMIE,NOMO2,FAM218A,PLXNB3,C11orf49,CDIP1,SEPT4,MBOAT7,FA2H,POU6F1,MED1,LRRN3,PTPA,EPDR1,MAPK7,BCAS3,WBP1L,ZSCAN32,PTPRB,OCIAD1,CASTOR1,PTPRZ1,NKAIN1,STRC,RAB3IL1,RAB5B,TMEM255A,NWD1,RASGRF1,ZMAT4,TRIM68,RGS3,ZNF532,SETD5,EXD2,RAVER2,ELP2,ARMH4,BAALC,ACER3,ABCA11P,ST6GALNAC6,KCNIP1,ATXN2,HOGA1,SCN3A,TNFRSF19,ASIC4,SELL,GALNT10,FOXRED1,MRAS,FERMT1,CPEB3,MYO18A,AMBRA1,FBXO11,ST6GAL1,ST3GAL3,NUBPL,LIMS2,KANSL3,SLC8A2,TMEM132D,ELMO2,EFHD1,ARFGAP1,EPC1,NAXD,ZKSCAN3,ZNF667,SMARCD3,INAVA,SNCB,MAPKBP1,WDTC1,KIF21B,SOX10,ZSWIM8,MYCBP2,DBNDD2,CDK19,TSPYL2,DDN,NFASC,CLSTN2,SSTR1,SSPO,SEPT3,JMJD6,SLC37A2,TACR1,MLST8,FBXW11,TMEM136,SMG6,TBX15,EHBP1,DMXL2,TCF7,SZT2,NAT16,TMEM151B,PCDHB3,NSD1,AKNA,TNS2,CYB561A3,RNF216P1,ATP13A2,FAM200B,LEFTY2,SLC44A1,ENHO,MTMR14,TMEM9,HEY1,KAT6B,PIK3R5,RBFOX2,RASD2,CDK20,NPL,TRH,ANO5,CLEC2L,FLRT1,PLEKHH2,PLPPR2,WIPF1,KLC2,ZIC1,CFAP52,TRIM9,ATP6V0E2,NDRG4,POLR3H,EML6,UPF3A,DHX33,EMSY,PRDM2,NT5M,LINC02210,STOX2,LMAN2L,RNF103,ADAMTS9,HPS4,ITM2C,MVB12B,DOCK8,UBE3B,PAK5,KAT6A,CASC15,ADAMTSL3,TRAM2-AS1,ZNF248,TIGD6,RNF170,PIANP" MicroRNA hsa-miR-520h:mirSVR_highEffct hsa-miR-520h:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.93E-139 3.33E-135 9.57E-138 8.82E-137 336 1324 "RALGAPA1,SYN3,CSMD3,KLHL32,ESYT2,BEND6,NLGN4X,SLC24A4,ZNF608,INTS2,RTL9,KIAA1324,WDR35,ALCAM,GPRASP2,PARG,APC,CDK13,STK33,EIF4G3,ATP2A2,ATP2B1,NOL4,ADGRB2,ADGRB3,MPDZ,FUBP1,JAZF1,SGCE,OSGIN2,CALB2,CAMK2D,SLC25A14,CAST,HIP1R,CERS5,CBFA2T2,MAGI1,CCPG1,CLGN,B4GALT6,LHX2,RAB28,ABCG2,DNAJB5,CNR1,AKAP7,ARMC8,FAM149A,AHCTF1,ACBD5,CDC42BPB,CREM,ENTPD4,ANKRD44,GDA,LRRC3B,CSNK1E,OSBPL3,CTNND2,RUBCN,GPRASP1,RIPOR2,DBN1,HEPH,TIAM2,DDX46,RHOBTB1,SNAP91,G3BP2,DLG2,RAB39B,USP3,DMTF1,DNAJB6,DYRK1A,DNM1L,ABCC9,FAM135B,EDNRA,ATL1,FCF1,RASGRP1,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,IRAK4,COPS4,PLEKHA1,C8orf37,DCTN4,TUBD1,EPB41L2,EYA1,F3,CLVS1,WAC,ACSL4,SCML2,CEP78,FDFT1,GTF2IRD2,FGF12,FOXG1,FOXF2,RGPD5,IQCG,ANKFY1,C2orf88,EFCAB2,JKAMP,TRMO,NBEA,ATP6V1H,KHDRBS3,PNMA2,MSANTD4,MPP6,OGA,HRASLS5,HBS1L,INPP5K,GK,TCERG1,COPS8,TOX3,TNRC6A,ZNF638,DCLK2,GOLGB1,GPM6B,FUT10,DIDO1,GRIN2C,GRM5,GRM7,ZNF496,CIT,PTPN5,GSTT2,LINGO1,MAEL,HAS2,HPS5,MAN1B1,ARHGAP19,TLX1,OPALIN,MSL1,C5orf24,IGSF1,ZNF678,LRRTM3,ITGAV,JAK1,METTL21A,OLFM3,KCNC1,KCNN2,KLC1,IPO5,TTYH2,LIMS1,HECTD2,ZFYVE27,MAP6,MAT2A,MBNL1,MEIS1,SRSF12,MEST,MID1,ERICH3,RSPO2,MXI1,MYCN,RTL5,NAP1L3,NCAM1,NCAM2,SLC11A2,HCN1,SETD4,OCRL,OGG1,OLR1,LOC100128398,GPR137C,PAH,PAK3,CNTN3,PCDH8,PRTG,PDE4A,PDE4D,CDK14,HERC2P3,ANLN,FAM216A,PLP1,C11orf49,PPP3CA,PPP3CB,KANSL1,PKIA,PKN2,HYDIN,WBP1L,SIDT1,CNTLN,PLPPR1,PTHLH,PTK2,PTN,TMEM260,PTPN13,PTPRO,RAB5B,ZNF793,DBX2,MSANTD2,ZYG11B,RFX3,RFX4,RGS3,RGS7,SEC61A2,RNASEL,CARF,ROBO1,ELP2,TMEM100,FBXW7,ACER3,ATAT1,KCNIP1,RYR3,DGLUCY,SALL1,ATXN7,LRFN5,HOGA1,FAM19A1,SCP2,TNFRSF19,HSPA4L,SH3GL3,FERMT1,CPEB3,MAGI3,CHD9,FBXO11,FHOD3,NLGN1,SLA,ZNF365,BTBD3,DHX30,SEPHS1,ARHGEF40,EFHD1,GKAP1,SORCS3,DMRTC1,CDK5RAP2,RIMS1,ZNF415,FAM126B,SPP1,ERC1,ZBTB43,NPAS3,ITPRID2,MESP1,SAMSN1,ZC4H2,SS18,ELOVL4,SEPT8,ARHGEF9,PLCB1,SYT1,DDHD2,CAMSAP2,FBXW11,TCF4,SATB2,TCF12,RALYL,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,AP4E1,THRA,GZF1,HEY1,ZFP91,TMPO,RIMBP2,TPM1,TPM3,TPM4,ZNF384,PRMT8,PDSS1,AMACR,ZKSCAN5,GORASP1,PLEKHH2,VLDLR,TBC1D15,LAT2,CLDND1,SLC47A2,ZNF74,WNK1,CA10,PCDH15,FIP1L1,FAM47E,RTN4,PHTF2,ADAMTSL3,JMJD1C,FRMD6,DPF3,SLC4A10" MicroRNA hsa-miR-1:mirSVR_lowEffct hsa-miR-1:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.87E-139 3.86E-135 1.11E-137 1.02E-136 392 1793 "SYN3,CLK4,EMILIN3,CSMD3,FMNL2,KLHL32,SORCS1,ADORA3,OLMALINC,AP1B1,INTS2,GPR158,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,HFM1,SEMA6A,PCDH10,UNC79,FAM135A,SYT13,ZNF687,AMPD3,AMPH,AMT,CDC42BPA,LRCH2,CACHD1,VAT1L,TNRC6C,SHTN1,LGR5,PPP4R4,PDXK,CASK,TMEFF1,ARNTL,CHRD,DYNLL1,RNF182,NOL4,ATP6V0A1,TTLL9,ADGRB3,BCL2L2,BCL7A,SYNJ2,ARHGEF7,SCAPER,GYG2,SGCE,C5,WASF1,MYRF,MMD2,BTRC,CA12,CACNA1A,CACNB2,CALB1,PTBP2,NGB,SYT6,PRC1,METTL6,P2RX6,ENTPD6,CDH2,SRSF11,CHM,CASC2,LSMEM2,NRXN1,FBXO7,TJP2,FADS2,QKI,NIPBL,LETMD1,AKAP5,TBPL1,SMARCAL1,CNRIP1,CLOCK,C2CD2,CRHBP,AKAP12,ANKRD44,CSF1R,ATRNL1,NCAN,CNTNAP2,SLITRK5,SDC3,KIAA0040,PHF14,RIMS2,GPSM1,HDAC4,TOX,ZNF337,TBC1D5,AIF1L,PITPNC1,C8orf34,ZBTB24,PLEKHM1,MYEF2,KIAA0319,MAGI2,SPOCK3,SRGAP3,FAM107B,KIF19,DLG4,HS3ST4,DMPK,USP3,CDON,DNM2,GNE,DYRK1A,GOLT1B,EBF1,EDIL3,FAM135B,HEYL,KLHL5,TMTC1,YAF2,SH3GLB1,ABI2,KCTD3,EIF4G2,EIF5,PLEKHA1,RGS17,EMX2,EPB41L1,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,CLVS1,FAM198B,WAC,RPS6KC1,SH3YL1,PTK2B,ZIC4,TAOK3,FCGR1A,TESK2,ZNF589,FGF14,BAIAP2,RGPD5,SLC37A3,FLYWCH1,PDLIM5,NPTN,KHDRBS3,DLL3,TMEM151A,ZNF512,STAG2,GABRA1,GALNT15,ZMYND11,ZNF274,DISC1,ACSS1,CPLX2,MYOZ2,IGSF5,TUBGCP4,MSTN,CYP46A1,TOX3,KDM2B,GNAS,GNG4,FUT10,LILRA1,GPR22,TMEM121B,GRIA2,GRIK2,NR3C1,PRDM5,GRM7,BTN2A1,GSTM5,ADAMTS6,IRAK3,UBE2QL1,KLF12,BACH2,ELOVL5,ACOT7,HNMT,OPALIN,LRRC75A,SMAP1,IRF8,IDH3A,FAM95B1,KNDC1,LRRCC1,IL6ST,BRINP3,INPP5B,ITPKB,KCNMA1,KIF5C,LIFR,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,SYT9,KITLG,AFF1,MOBP,MOG,GIT1,SESN3,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM1,NCAM2,NDUFA5,ALDH1L2,VWA2,NTRK2,ZNF827,ZDHHC22,GLIPR1L2,PAX6,PBX1,PRTG,GPR85,FAM218A,EPB41L4B,TNPO2,PPP2R2B,PPP2R5E,RAB39A,WBP1L,SIDT1,GON4L,CNTLN,PTPRN,ZNF793,RALGDS,FAT4,ZDHHC14,ZYG11B,REV3L,RGS3,RIC8B,ZFHX4,RERGL,CYB561D1,TMEM100,NEK11,ZNF671,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,ATXN2,LRFN5,HOGA1,SCN3A,LINC00461,GALNT10,SFPQ,SUPT20H,SGK1,PPP1R9A,KIF16B,DOCK10,NTNG1,CHD9,FBXO11,ST6GAL1,SYBU,NUBPL,SLC6A8,SLC8A2,SLC8A3,SLC9A5,SHANK2,SLC12A2,TMEM132D,SLCO1A2,ZFP1,SMARCA4,SMARCC2,LIMCH1,MAPKBP1,TMCC1,FAM126B,DOP1A,TNIK,SOX10,NMNAT2,CLUAP1,ENKUR,HECW1,NFASC,C11orf87,SRPK2,EPB41L3,MPRIP,ELOVL4,SEPT3,FAM168A,SUPT5H,SYNE2,VAMP1,C3orf70,SYN1,C12orf76,TAL1,UNC5D,AGTPBP1,SATB2,TCF7L2,SYNE1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,AHCYL2,CCDC173,ZFPM2,CRB1,AP4E1,TGFBR3,TK2,ACTR6,DDHD1,BEX4,RIMBP2,CSMD1,TNR,PIK3R5,TPM4,ANKRD20A2,TTTY15,HEPACAM,CADM1,RPRM,SLAIN1,BEST1,VSNL1,WIPF1,RICTOR,ZIC1,ZNF711,MKRN3,ZBTB38,ANKS1B,PLPPR5,UPF3A,PRDM2,LRP8,PCDH15,FIP1L1,WIPF2,C12orf4,ST7,KAT6A,HNRNPA3,ZNF248,FXR1,NETO1,ST8SIA2,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-411*:mirSVR_highEffct hsa-miR-411*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-138 6.76E-135 1.93E-137 1.78E-136 321 1210 "CLK4,NCKAP5,PTCHD1,KIDINS220,KLHL13,RTL9,CC2D2A,TAOK1,ALCAM,LRCH2,GPAM,BCAS1,TNRC6C,APP,MIER1,CAPRIN2,ASPH,ZBTB10,NCOA1,TMEM108,ATP1B3,NOL4,DPY19L3,SEC11C,AP1M1,SGCE,WASF1,CACNB2,KALRN,MTMR7,CD86,SYNGR3,CDC42,CDH2,LRRFIP1,LARGE1,MAGI1,DLGAP1,SRSF11,CHN1,NDST3,PLAA,NRXN1,FBXO7,ARMC8,COL4A5,SLC25A27,AKAP5,ACBD5,SLC35F1,SEC31B,CLOCK,RBM39,SH2B1,FEZ1,CSNK1G3,ATRNL1,PDE4DIP,FAM169A,CTNND1,RIMS2,CCDC144A,CYBB,KATNAL2,LIN54,TOMM20,PABPC5,ELMSAN1,C8orf34,HP1BP3,CEP170,GSDME,SACS,SPOCK3,RABGAP1L,SEC16A,GRIN3A,DMD,DMTF1,ECM2,DYRK1A,ABCC9,EDNRB,FCF1,RASGRP1,FSD1L,YAF2,EIF4G2,TENM1,PLEKHA1,TMEM35A,C8orf37,CALCRL,EN2,ENPP6,SRRM1,RRAGB,SEC24B,FER,KIAA1109,POLR1B,CAMSAP1,POLK,SUCO,IP6K2,RGPD5,NELFCD,C2orf88,PDLIM5,ATP6V1H,DACH2,PHYHIPL,GABRG2,CAB39,ZMYND11,ATP8A2,INPP5K,ARFIP1,PPARGC1A,MALT1,SPIN1,GLS,ZNF638,KIAA1958,KDM2B,HTATSF1,ADGRA3,GRM3,GRM7,PSIP1,GUCY1B1,MAP4K5,WIF1,RASSF8,FRMD3,ATXN2L,HMGB1,AGBL5,SMAP1,LIX1,ZNF678,LRRTM3,KCNK1,PAXBP1,HECTD2,MAP4,MBNL1,IL17D,CHIC1,MEIS1,MEIS2,MITF,WDR49,CD200,MSI1,ADAM22,BCO1,MTTP,MYCN,MYO9A,HNRNPM,IDNK,NEFM,NEK1,DNHD1,CLEC9A,NRCAM,GLIPR1L2,CNTN3,PRTG,SLC10A4,GNG2,OLA1,SNX10,RETREG1,HMGCLL1,PMP22,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R2C,CRLS1,PPP3CA,KANSL1,HYDIN,SIDT1,MDGA2,PSMD13,CNTLN,BDNF-AS,TMEM260,PTPRB,OCIAD1,PTPRD,C1orf109,PPP2R3C,PID1,USP47,ACSS3,OXR1,KHDRBS2,RDX,SLC6A15,GTDC1,FIGN,RFX3,ARHGEF10L,SEC61A2,NUDT11,PBRM1,RNASEL,ZFHX4,ZNF532,CARF,RORB,ATP8B4,ADAL,ACER3,SALL1,SEMA6D,SATB1,HOGA1,SCN3A,LINC00461,SCP2,FNIP1,ELMOD1,SUPT20H,SGK1,ITSN1,NLGN1,CLSTN1,WDR47,RUFY2,KDM4D,SEPHS1,SHANK2,SLC12A2,SLC15A2,ATF7IP,SLCO1A2,SPHKAP,ZFP1,SMARCA4,CMTR2,SNRPN,SOX3,SP4,CLUAP1,ENKUR,KDM4C,RBM26,LMO3,ATP10B,TROVE2,NKAIN2,ELOVL4,TTBK2,PHLDB1,SYNE2,VPS13A,SYPL1,MTCL1,CAMTA1,MCF2L,EXOC7,FAM208A,TBCEL,TMEM136,ANO4,TCF7L2,ZEB1,RPGRIP1L,SYNE1,PCDHB10,PCDHB6,PCDHB3,FRYL,TEX15,PMS2CL,HHIP,SLC44A1,TJP1,ASXL3,TLL2,HEY2,TPM4,RGMB,TRO,TRPC1,CLHC1,CADM1,UBE3A,AMOT,UGT8,PLEKHH2,WRN,ZNF711,MICU3,KCNT2,TCEAL7,ANKS1B,FTSJ1,PLPPR5,CADM2,PRDM2,RGMA,STOX2,RNF103,ADAMTS9,PDSS2,GOPC,AMN1,DOCK8,PHTF2,JMJD1C,SSPN,FXR1,NETO2,NETO1" MicroRNA hsa-miR-548v:mirSVR_lowEffct hsa-miR-548v:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-138 8.16E-135 2.33E-137 2.14E-136 361 1531 "CPNE2,ASIC1,NCKAP5,ARID1A,CSMD3,PSMG3-AS1,SLITRK1,SORCS1,ERMN,PWWP2A,KIAA1211,RNF150,ESYT2,LRFN2,BEND6,NLGN4X,KLHL13,CC2D2A,SEMA6A,PCDH10,BBOX1,BEGAIN,AMPH,C6orf89,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,TMEFF1,ASPA,ASPH,ATP1A1,ATP1B3,TTLL9,BCHE,SGCE,OSGIN2,CACNA1D,CANX,CAST,METTL6,ZBED1,CDC42,CDH2,CDH10,CDO1,CLGN,SRSF11,CHGB,SYNPR,NDST3,NMT2,QKI,NIPBL,FHL5,ARMC8,AKAP6,SLC4A8,COX4I1,ACBD5,ZFP28,IGDCC3,MFSD4A,ZNF385A,CPS1,SEC31B,CRHBP,HAPLN1,CRY2,TENM4,RGS6,SOCS5,SLITRK5,UBXN2A,USP6NL,GPRASP1,RASSF2,TBC1D5,KIAA0586,MAML1,PHYHIP,TOMM20,PABPC5,PITPNC1,SPATA2,KLHL3,ZC3H11A,DDX46,SV2A,RABGAP1L,TRAPPC9,DYNC1I1,DMTF1,CASP8AP2,DYRK1A,ABCC5,GOLT1B,EBF1,EDNRA,TMTC1,SUGP2,EGFR,KMT5B,EIF4G2,CALCRL,DENND4A,ABCA8,TMEM132C,EFEMP1,SEC24B,GTF2IRD2,FGF14,FGR,SUCO,UBE2E3,MEX3B,CAP2,PCYOX1,IQCG,FOXO3,ATP13A4,ANKFY1,JKAMP,DPYSL4,TMEM107,KHDRBS3,CELF1,DACH2,SARAF,TPPP3,GAB1,HRASLS5,GABRG2,RAPGEF6,SALL3,NCKAP1,WASF3,GATM,SULT1C4,GDF9,RNPS1,HPGDS,GLS,GNAL,LOXL3,GNAO1,FERMT2,GPD1,GPD2,GPM6A,STON1,MCHR1,GPR37,PCLO,RAPGEF4,PLCD4,RFFL,GRIK1,NR3C1,CIT,LINC01089,PSIP1,RNFT2,PADI2,ZHX1,KLF12,ELOVL5,AGBL5,LRRC75A,LRRCC1,KIAA1755,IL11RA,ZNF678,ZNF385B,ITPKB,KCNA4,KCNA6,KCNH1,KCNK2,KTN1,PAXBP1,HECTD2,PIK3AP1,MAP6,MAT2A,MBNL1,MBP,MDM4,KITLG,MITF,MOBP,ERICH3,MRPL42,ADAM22,SCG3,MYO9A,NEXMIF,NAP1L2,ZC3H12B,CCDC13,NEK1,NEUROD1,SLCO1C1,CNOT4,NPR2,NRCAM,NTRK2,IGSF11,OCRL,ZNF713,PBX1,PCSK5,PDCD2,PDE3A,PDE4D,PDGFRA,GNG2,PFKFB2,OLA1,A2ML1,CCSER2,XRN1,FTO,SMOX,PRIMPOL,SCHIP1,MAGEL2,ING3,NXPH1,POLR2F,PPARA,PPM1B,PPP2R2B,LRRN3,PTPA,BCAS3,CNTLN,ANKHD1,PLPPR1,PTK2,PTN,PTPN13,PTPRN,PTPRZ1,TMEM231,RAB3A,USP47,ACSS3,ATG16L1,RAP1GDS1,ARID4A,RBBP6,KHDRBS2,RDX,ERI2,FIGN,RFX5,RIT2,MRPS18A,SETD5,C12orf49,KIRREL1,RORB,MRAP2,RPE,RPL15,ARMH4,MCMBP,PRR5L,ACER3,SAFB,LINC00461,TNFRSF19,IL17RB,SELL,FOXRED1,NLGN4Y,ITSN1,FAM102A,SH3GL3,KIF16B,ASAP3,CPEB3,FNDC3A,ST3GAL3,BTBD3,SEPHS1,NAPB,SLC15A2,LGI3,SNAP25,SNCA,MYO16,SON,WDTC1,SOX3,SOX5,BDP1,PEG10,KIF1B,SPART,LHPP,C11orf87,CLASP2,CLSTN2,NKAIN2,SEPT8,SYT11,FGD4,MTCL1,CAMTA1,AGTPBP1,TBCEL,EHBP1,TCF4,ZEB1,TPCN2,WDR7,SLC19A3,AKNA,CCDC173,ZFPM2,AKTIP,TLL2,ERCC6L2,TNFRSF1B,TP53BP2,RBFOX2,TPM3,TRPC3,RUSC1,RPRM,SLC35A4,GORASP1,FAM181B,NSD2,KLC2,XPO1,ZNF24,ZNF70,FMN2,PLPP4,NDRG4,ZBTB38,EML6,ZFAND5,CA10,EMSY,XKR7,TUBA1A,SCG2,FIP1L1,SLC17A6,MVB12B,EPM2A,FAM13C,FZD3,NUP214,GAN,FAM198A,SENP7" MicroRNA hsa-miR-4289:mirSVR_lowEffct hsa-miR-4289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-138 1.04E-134 2.96E-137 2.73E-136 384 1728 "RALGAPA1,ASPHD1,KDM5D,ARID1A,CSMD3,BRAP,BEND6,NLGN4X,SLC24A4,NME5,OSBPL6,LRRC7,SPARCL1,BBOX1,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,MAGEE2,UPRT,GPAM,DGKD,CACHD1,BCAS1,SHTN1,MIER1,TMEM263,RASL11B,EIF4G3,ATP2B2,B3GALT2,N4BP2L1,NOL4,ADAM15,BCHE,BID,BMP7,FUBP1,CACNA1B,DDR1,CACNB2,CACNB4,THSD7A,CALM1,PTBP2,CAMK2G,SLC25A14,CAST,SPAG9,NFS1,CBR1,INA,LRBA,LGI1,DLGAP1,COPB2,CHGB,CHN2,CASC2,QKI,TMEM155,CNTN1,AKAP7,ARMC8,FAM149A,BTF3L4,SLC4A7,IFFO1,CP,SEC31B,SNCAIP,MICAL2,OSBPL3,CSNK1G3,PLXNA4,CYBB,ARHGAP32,ZNF337,KCTD8,TMEM170A,PABPC5,DNAJC6,JAKMIP2,ZBTB24,MFAP3L,FBXL5,KIAA0319,PLPPR4,SNAP91,SRGAP3,G3BP2,EXOG,RAB39B,DMTF1,DPP6,ARRDC4,ECM2,MAMLD1,DNAJB6,GOLT1B,E2F5,EBF1,FAM135B,EDNRB,ATL1,SEMA3D,KLHL5,PHF20L1,KMT5B,EIF4G2,RGS17,DCTN4,ANKRD13B,EPS8,NCALD,CDHR1,RTN3,EYA1,MRVI1,F5,ARMCX1,CLVS1,ZIC4,FCGR1A,CHST15,FGF1,POLR1B,FGF12,SUCO,UBE2E3,MEX3B,FOXF2,FLT1,ANKFY1,SGIP1,C2orf88,EFCAB2,POMT1,TMEM107,NSG2,MPP6,PHYHIPL,STAG2,HRASLS5,GABRA5,CHL1,CAB39,HBS1L,IQGAP2,DISC1,CPLX2,MYOZ2,SULT1C4,MSTN,ARFIP1,PPARGC1A,DBF4,HTATSF1,GNAS,GPD2,PRUNE2,GPM6B,LILRA1,LPAR4,NUDT21,RAPGEF4,GRM8,LINC01551,MAP4K5,IRAK3,C1orf94,NXPH3,NCKAP1L,HLF,ELOVL5,AGBL5,HSF2,CELF5,IGF1,C5orf24,DOCK7,LIX1,IL6ST,DIPK1A,ZNF385B,LRRTM3,NME9,KCNJ3,KCNK2,CREG2,STMN1,PAXBP1,LSS,SMAD9,CLEC18A,LYPLAL1,MAT2A,ADAM11,IL17D,LRP1B,MEF2C,MEIS1,AFF1,MMP16,MOBP,ERICH3,GIT1,CCDC80,MSR1,LAYN,NAP1L1,NELL1,NF1,ALDH1L2,NOVA1,DNHD1,PCBP3,NTRK3,NUCB2,OLR1,OPA1,SNTG1,PBX1,PCDH8,PCSK1,PDE1A,PDE4D,PDGFRA,PIK3R1,FAM216A,MTRF1L,LRP12,SCHIP1,MBOAT7,FAT3,POU3F2,DRAM2,MED1,MINDY2,CRLS1,PPP2R5C,PPP2R5E,PPP3CA,PPP3CB,EPDR1,MAPK9,MAPK10,FITM2,VPS13C,APTX,SIDT1,GON4L,CNTLN,PTN,TMEM260,ZSCAN32,PTPRD,FAM120C,ZNF844,RAD17,ZNF793,SH3TC2,ENOX1,KHDRBS2,RDX,RET,REV3L,PRRT2,RFX4,RGS3,SLC25A36,ROBO1,CCDC25,UEVLD,RPS6KA2,RYR3,ZNF331,CCDC112,AP1AR,SAFB,SATB1,TNFRSF19,MRAS,NLGN4Y,CHD9,SYBU,ST3GAL3,SEC31A,LRRC55,CCDC88A,SLC12A2,SLCO1A2,SORCS3,MAPKBP1,CMTR2,SNRPN,MYO16,WDTC1,MYT1L,SP4,HECW1,KDM4C,TEX2,KIF1B,TSPYL2,RBM26,LMO3,C11orf87,POGZ,SSTR2,ELOVL4,CEP68,TTBK2,RGL1,DIP2A,NSFL1C,KLHL7,NECAB1,MLC1,ZC3H4,SYNE2,ARHGEF9,C3orf70,PJA1,EXOC7,TBCEL,KLHL4,ACSL6,ZFP90,TCF7L2,ZEB1,TCF12,WASHC4,WDR7,SYNE1,RALYL,SLC19A3,RNF175,TEX15,CYB561A3,SIRT1,ZFPM2,C18orf54,ITGB3BP,AKTIP,TLL2,TMOD1,R3HDM1,TP53BP2,C9orf85,PRMT8,TRO,DCBLD1,RFTN2,FAM155A,UBE2H,UGT8,DNAJC12,SLAIN1,P2RY12,NSD2,WRN,RICTOR,XRCC4,ZIC3,KCNT2,FMN2,PLPP4,MKRN3,LYPD6,FSTL5,EML6,ANKS1B,ZFAND5,SMARCAD1,PRDM2,CSDE1,STMN4,MDH1B,FZD3,PAK5,HNRNPA3,FBXO36,NETO1,SLC4A10" MicroRNA hsa-miR-581:mirSVR_lowEffct hsa-miR-581:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.96E-138 1.10E-134 3.12E-137 2.88E-136 379 1685 "ASIC2,ABHD6,NCKAP5,GRAMD1B,PTCHD1,KCTD16,NR0B1,C1QTNF3,LRRC7,ALCAM,PCDH10,MRTFA,AMPD3,ANK3,MAGEE2,GPAM,PHYHD1,BCAS1,API5,PDXK,CDK13,NUMB,INSYN2B,CHID1,STX16,RNF182,N4BP2L1,DPY19L3,ADAM23,LINC00847,DCAF5,CFLAR,ST3GAL5,FUBP1,SGCE,LDLRAD4,CACNA1A,CACNA1B,KALRN,RUNX1T1,CBFA2T2,SEPT7,ZBED1,CDC42,CCPG1,CHGB,TAOK2,LHX2,SLC22A6,KMT2C,RAB33A,IGFBP7-AS1,CLCN3,ABCG2,AKAP6,TRIM69,SNCAIP,RGS6,ATRNL1,CST3,SDC3,PPP6R2,ZSCAN23,DCAF4,FAM131B,CCDC144A,BOC,FRMPD4,TOX,KIF26A,LONRF1,TM9SF4,DGKG,TMEM170A,GIT2,SIRPA,JAKMIP2,ZEB2,CNIH3,KIAA0753,KLHL3,ZC3H11A,GSDME,DDX46,SPOCK3,SRGAP3,ZNF582-AS1,DLX1,RAB39B,USP3,DMTF1,ACOT8,DTNA,DUSP9,DYRK1A,DNM1L,FAM135B,SYT15,SEMA3D,FRY,EIF4G2,SORBS3,EIF5,TENM1,ELAVL4,C3orf18,TMEM35A,VPS13B,EPHA5,RAB9B,EPS8,IGSF6,TMEM74,TLR7,RRAGB,F8,CACNG2,ACSL4,PTK2B,DLC1,TOMM40L,FKTN,STRADA,TESK2,GORAB,SEC24B,MED12L,FGF12,FGFR1,SUCO,UBE2E3,SYNCRIP,FOXO3,PSD2,NOP56,C2orf88,SPECC1,FAM49B,ATP2C1,KHDRBS3,ST6GALNAC3,ADGRA1,NRG3,FYB1,HRASLS5,GABRA5,ZMYND11,IQGAP2,ERAP1,TMEM8B,MYOZ2,TUBGCP4,ARFIP1,CYP46A1,ADAM28,GFER,MALT1,SPIN1,ZNF638,CBX1,KIAA1958,DCLK2,GNAO1,GPM6B,STON1,LPAR4,CECR2,PCLO,GRIA2,DIDO1,GRIA4,GRID1,NR3C1,CIT,BTN2A1,AP4S1,RABL2A,WIF1,MAEL,RASSF8,PADI2,MAN1B1,MIER3,HLF,TLX1,AGFG1,LRRC75A,SMAP1,ATCAY,IGF1,USP54,SLC6A17,LRRTM1,ITPKB,SLC35G1,KCNA1,KCND2,KLC1,CYP27C1,STMN1,ZFYVE27,MARK1,MARK3,LRP1B,MEIS2,KITLG,MID1,AFF1,AFDN,XRRA1,ZNF680,ADAM22,PTOV1,MTTP,NCAM1,NDP,NEUROD1,NFE2L2,ALDH1L2,PCBP3,CLEC9A,NTRK2,OPCML,OXTR,ZDHHC22,KCNK10,CNTN3,DPY19L2P2,PCMT1,PDE1C,GPR173,PIK3R1,PLIN1,PSAT1,SDK2,SEPT4,NXPH1,MED1,MINDY2,PPP2R5C,PPP3CB,RASGEF1B,CEP41,BCAS3,SLC22A23,PLPPR1,NCR3LG1,BDNF-AS,PTHLH,ELOVL2,PTN,EML5,TMEM231,SH3TC2,DPF2,REV3L,ERI2,FIGN,RFX2,TTLL7,SETD5,ROBO2,SNX22,NEK11,BAALC,ZC3H14,SGSM1,PRR5L,PTGR2,MEG3,KCNIP2,RTN1,FAM182A,SATB1,HOGA1,SCP2,GALNT10,SH3GL2,NTNG1,MAGI3,FHOD3,SLITRK3,DHX30,KANSL3,LRRC55,TRIM67,SLC15A2,BTBD7,ZFP1,GKAP1,ANKRD36,MBD5,ZNF415,WDTC1,BDP1,IDI2-AS1,UNC5B,PEG10,SPART,C11orf87,PBLD,MAPK8IP3,STAU1,ELOVL4,NEK4,SYT11,FGD4,SUPT5H,PLCB1,ANKRD28,SLC37A2,MTCL1,DDHD2,ANO4,EHBP1,WSCD1,VWC2,SATB2,ZEB1,TRIM2,TCF12,SYNE1,PHF24,SLC19A3,USP32P1,TNS2,AHCYL2,PMS2CL,DICER1,SIRT1,ITGB3BP,MTMR14,TK2,TLR4,NR2E1,LRRC8A,TP53BP2,RBFOX2,TPM3,PRMT8,PDSS1,ZMYND8,ANO5,RFTN2,FLRT2,ZNF709,BEST1,VSNL1,WIPF1,KLC2,RICTOR,GUSBP1,MICU3,PLPP4,GPR158-AS1,SLC26A10,EML6,DPYSL5,ZNF213,CA10,EMSY,PRDM2,PRDM8,PCDH15,NAV3,FAM47E,WNK2,PLSCR4,PARP11,C12orf4,FAM13C,KAT6A,FBXO36,CERS6,ADAMTSL3,TIGD6,SNX14,NETO1,ST8SIA2" MicroRNA hsa-miR-891b:mirSVR_lowEffct hsa-miR-891b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.26E-138 1.27E-134 3.59E-137 3.31E-136 361 1533 "ACLY,NCKAP5,ACTN2,NDRG3,TMEM132B,GALNT13,ADD1,ADD2,ADD3,SLC44A5,AP2A2,PCDH19,LRRC7,ALAD,SEMA6A,BCAR3,ARHGAP20,UNC79,DPP10,LCORL,PHF12,TNRC6C,USP37,SEMA4G,TMEM263,IGDCC4,ZFYVE28,ARHGAP5,MARK4,ZSCAN18,CCAR2,TMEM108,EIF4G3,RNF182,N4BP2L1,BARD1,MIR9-3HG,KSR1,DST,SYNJ2,FUBP1,LINC00906,SGCE,LDLRAD4,BTRC,CACNA1A,KALRN,VSTM2A,TMEM257,LRBA,SEPT7,LARGE1,MAGI1,MS4A7,LHX2,CLTC,QKI,SRP14-AS1,NIPBL,CNN3,ARHGEF6,ARMC8,RCHY1,TOGARAM2,FAM171B,CRHBP,RNF14,ANKRD44,NCOR1,GDA,SNCAIP,SEC24C,SIPA1L1,SLITRK5,UBXN2A,RIMS2,ZSCAN23,RIMS3,DAPK1,TOMM20,GIT2,SIRPA,ARMCX2,HP1BP3,CEP170,KLHL3,WDR20,DLG2,DMD,NYAP1,NR1D2,DNM2,DMTF1,DPYSL2,PDCD6IP,DSCAM,ECM2,DUSP9,KLHL5,RBM12,EFNB3,FAM13A,PHF20L1,EGFR,MBNL2,EGR3,KCTD3,EIF5,ELAVL2,USPL1,EN2,VPS13B,EPB41,EPB41L2,COQ7,DENND4A,ETV1,ADGRV1,ARMCX1,FCGR3A,KIAA1109,OLFM1,FGF13,PRKAG2,CAP2,SYNCRIP,ANKFY1,AFF2,DLL3,FYB1,STAG2,GABRA2,ZNF44,GALNT15,GAD2,HBS1L,DISC1,IGSF5,NEU3,SULT1C4,MMADHC,PPARGC1A,CRCP,GLRB,TOX3,STARD3,ZNF638,LUZP2,TMEM121B,GRID1,SPACA9,NR3C1,GRM7,RNFT2,PADI2,NXPH2,HLF,HMGCL,AGBL5,HNF4G,HSF2,MSL1,RBPJ,SCIN,INPP5B,ITGAV,ITPKB,JAK1,KCNA4,KCNH2,KCNK1,KCNMA1,KIF5A,LMO2,VWA5A,HECTD2,NCOA7,MAOB,MAP2,MARK3,MAT2A,MATN2,MBD1,MBNL1,MDM4,LRP1B,MID1,AFF1,AFDN,XRRA1,MMP16,WDR49,MOBP,CD200,THYN1,SCG3,HNRNPM,NEUROD1,NFIA,NFYA,NODAL,NOVA1,NTRK2,PAX6,PDE2A,CDK14,GDAP1L1,PIK3C2A,XRN1,GPSM2,PCDH18,STRN3,SCHIP1,SPATA6,EPB41L4B,SH3KBP1,CCDC144B,CRLS1,PPP3CA,PRKCB,MAPK9,PTCH1,PTN,PTPRB,SLC25A48,USP47,FAM66C,ZCWPW1,OXR1,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,ZYG11B,ZMAT4,RFX3,RGS7,PBRM1,ZFHX4,SETD5,CCDC102B,EPHA10,GLDN,TCP11L1,LGR4,PTGR2,ATAT1,WLS,TRAPPC13,AP1AR,RMI1,SALL1,SATB1,CSRNP3,ATXN1,ATXN7,LRRTM4,SCP2,PEAR1,SEC14L1,SCAF8,PPP1R9A,SHC4,FBXO11,FNDC3A,DZIP1,ABLIM3,PEX26,SLC6A11,SLC12A2,SLCO1A2,GKAP1,ANKRD36,SNRPN,PALLD,UNC80,USP33,TRERF1,SOX11,SP2,SP4,ENKUR,ERC1,SPTAN1,KIF1B,ZBTB43,RBM26,SRPK2,COLGALT2,EPB41L3,NKAIN2,ERBIN,ZSCAN29,NSFL1C,SYN2,PJA1,TAF9,UNC5D,TBCEL,FBXW11,ATMIN,TCEA1,NEU4,SATB2,ZEB1,TCF12,PCDHGA11,SYNE1,PUM2,FRYL,SIK3,FAM200B,ACTR6,ZFP91,FAM124A,RIMBP2,KCTD2,R3HDM1,TNS1,NPL,NR2C2,ZMYND8,PPIL6,RUSC1,CA14,TSC1,CADM1,RPL7L1,DNAJC12,MEAF6,WIPF1,GUSBP1,SF1,ZNF711,MKRN3,LYPD6,TCEAL7,TMEM237,DPYSL5,PLPPR5,SYNC,INTS3,WNK1,PRDM2,CSDE1,STOX2,ADAMTS9,SEMA3B,PCDH15,SNX27,PDSS2,FAM13C,DOCK8,RTN4,ADAMTSL3,JMJD1C,NHSL1,ZDHHC20,PIANP,IFT88,GAN" MicroRNA hsa-miR-2052:mirSVR_highEffct hsa-miR-2052:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.90E-138 2.19E-134 6.17E-137 5.68E-136 365 1569 "KCNH8,ASIC1,NBAT1,TKTL1,KDM5D,CSMD2,ARID1A,ADARB2,PSMG3-AS1,ADD2,ERMN,KIAA1211,PTCHD1,BEND6,DPY19L2P4,GPR158,BBOX1,GPRASP2,AMPH,BIN1,OGT,DPP10,ANK3,USP28,PHF12,PPFIA1,ANXA7,APAF1,TNRC6C,AQP4,MIER1,ZFYVE28,CADPS,MARCH3,EIF4G3,DPY19L3,BACH1,BCHE,PROM1,SYNJ1,SYNJ2,JAZF1,CALM1,PTBP2,ISPD,CLDN10,CDC27,CDH2,CLGN,UBE2L6,CFL2,RCBTB2,SOCS6,MS4A7,RAB33A,NRXN3,CLCN3,NRXN1,QKI,NIPBL,TMEM155,IGLON5,ARHGEF6,AKAP6,SLC4A8,ZFP28,SLC35F1,CPS1,PREPL,CSF2RA,ARHGEF10,MICAL2,CSNK1G3,SOCS5,CNTNAP2,FAM169A,GREB1,CYBB,DOCK4,HDAC9,ARHGAP32,RIPOR2,LONRF1,TM9SF4,DNAJC6,JAKMIP2,ZEB2,HP1BP3,BLOC1S6,RHOBTB1,RABGAP1L,CHRDL1,DRD1,EBF1,EDN1,EDNRA,EDNRB,ANKRD46,YAF2,CELSR3,FAM13A,PHF20L1,SUGP2,KMT5B,DCTN4,RCAN2,ENPP6,CDKL3,DNAJC27,RCSD1,F3,F5,ABCA8,TMEM132C,GORAB,SLC9B2,FER,SUCO,HPCAL4,SYNCRIP,C2orf88,SMC2,APOPT1,PDLIM5,DKK3,GAD2,ARPP21,DISC1,GART,IGSF5,TUBGCP4,SULT1C4,AHDC1,ADAM28,PPARGC1A,GK,GLS,PCDH11X,ZNF638,KIAA1958,MAP7D2,GNAS,ZNF782,FERMT2,LNX1,GPD2,RAPGEF4,GRIA1,GRIK2,NR3C1,GRM1,GRM5,GRM7,HLF,ELOVL5,HMGCL,LRRC75A,CELF5,HTR2A,C5orf24,USP54,LRRTM3,JAK2,KCND2,KCNJ3,KCNN2,LAMA2,LAMP2,LIG4,VWA5A,HECTD2,ARHGAP12,ZNF667-AS1,MAT2A,MBNL1,MBP,TM6SF1,LRP1B,SRSF12,KCTD6,AFDN,MMP16,MOG,ERICH3,CTNNA3,NAP1L1,NASP,NCAM2,NDUFA5,SFR1,NEFM,NEUROD1,NNAT,SLC11A2,HCN1,NTRK2,SETD4,IGSF11,OCRL,GPR88,OPA1,PAK3,PCSK1,PDCD2,BEST3,PFKFB2,SERPINE2,PIK3R1,ZNF655,SNX10,PLP1,MTRF1L,STRN3,PACSIN1,POU3F2,TATDN3,PPP2R5C,PPP3CC,PRKACB,PRKCB,GRAMD1C,HYDIN,DIRAS2,VPS13C,CNTLN,PTCH1,PLPPR1,BDNF-AS,TMEM260,EML5,PEX2,TMEM255A,SH3TC2,RAP1GDS1,ZNF493,RDX,ZYG11B,ERI2,FIGN,RFX2,RFX3,UBR7,SEC61A2,PBRM1,RNASEL,RPRD1A,CCDC82,CARF,GSTCD,ROBO1,UEVLD,FBXW7,MCMBP,ATP8B4,KCNIP3,CLIP1,RTN1,SALL1,SEMA6D,ATXN7,FNIP1,SMPD3,PEAR1,TRA2B,SH3GL2,CHD9,FBXO11,ZNF365,SLC1A3,PPP4R3A,RUFY2,ATF7IP,SPHKAP,ZKSCAN3,ANKRD36,LIMCH1,RIMS1,ZNF415,PALLD,UNC80,SON,DOK5,SP4,GLT8D1,EMC1,CAND2,UHRF1BP1L,KDM4C,RBM26,SPART,TAB2,ATP10B,LRRC4,SEPT8,TTBK2,KANK1,NECAB1,SYNE2,SYT1,POPDC3,MCF2L,FAM208A,UNC5D,TBCEL,ATMIN,TCEA1,VWC2,SATB2,TRIM2,CLASP1,PCDHGA11,SYNE1,SLC19A3,PUM2,GPRIN3,SIK3,ZFPM2,THBS4,SLC44A1,TIAM1,MTMR14,BHLHB9,ZFP91,NR2E1,TMPO,R3HDM1,CSMD1,PARD3,KAT6B,NPL,TPM3,C9orf85,CADM1,FAM155A,UBE3A,USP1,TBC1D15,CLDND1,ZIC3,KCNT2,CRB2,ZBTB16,TMEM237,EML6,ANKS1B,PRDM2,LRP8,STOX2,NAV3,SNX27,KCNAB1,FIP1L1,MVB12B,C12orf4,FAM13C,AMN1,CASC15,NUP214,TIGD6,SSPN,KLHDC1,FXR1,FRMD6,IFT88,SLC4A10" MicroRNA hsa-miR-590-5p:mirSVR_highEffct hsa-miR-590-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.56E-138 2.56E-134 7.19E-137 6.62E-136 330 1285 "RALGAPA1,SDE2,ABAT,TKTL1,ADCY2,CCDC85A,ESYT2,PTCHD1,KIDINS220,DPY19L2P4,ZNF608,CASKIN1,PCDH19,OSBPL8,ADGRF5,ARHGAP20,AMPD3,KIF6,OGT,DPP10,LCORL,APAF1,ALS2,USP37,ARHGAP5,MTMR9,N4BP2L1,BCL7A,ARHGEF7,FUBP1,BTK,MTMR2,SGCE,PTBP2,MAP7,KRIT1,USP6,INA,CFL2,SRSF11,SOCS6,CASC2,CNOT8,KMT2C,NRXN3,PLAA,C4orf33,NIPBL,CNTFR,CNTN1,AKAP7,ARMC8,AKAP6,BTF3L4,SLC4A8,ABI3BP,SLC35F1,FAM171B,PREPL,RBM39,NCOR1,GDA,TRIM69,AATK,SNCAIP,OSBPL3,ATRNL1,SOCS5,PHF14,GREB1,EDRF1,CX3CR1,ARHGAP32,RIPOR2,ARHGAP24,LONRF1,DGKB,TMEM170A,PABPC5,AIF1L,PITPNC1,COPS7A,MED24,TMEM130,ZNF582-AS1,GRIN3A,DMD,HS3ST4,CDON,DNM2,RCAN1,DNM1L,ABCC9,EBF1,EDNRA,EDNRB,ANKRD46,RASGRP1,FAM13A,PHF20L1,EGR3,PLEKHA1,PAN3,PLEKHO1,EPB41L1,RCAN2,KCNMB2,TMEM74,ARMCX1,FAM198B,ZNF461,SCML2,ST3GAL6,TESK2,KIAA1109,FGF1,POLK,ATP13A4,SGIP1,EFCAB2,SORBS1,ZBED3,PDLIM5,TPK1,NPTN,ARFGAP2,PNMA2,SARAF,STAG2,MEGF11,CHL1,GABRG2,ARPP21,SALL3,NEK6,DISC1,KIAA1841,NEU3,SULT1C4,MSTN,SESN1,MALT1,LUZP2,PSRC1,GPD2,GPM6B,DIPK1C,RAPGEF4,GRIA2,GRIA4,RFFL,GRM1,KIF3A,FAM107A,RASSF8,HPS5,FRMD3,NCKAP1L,HPSE2,HNMT,HNRNPK,NEGR1,CELF5,RBPJ,IL12A,SLC35G1,OLFM3,KCNC2,KCNN3,STXBP5,NCOA7,SMAD1,MARK1,LYPLAL1,MAT2A,MATN2,MBNL1,MEIS1,MOBP,ZNF680,ADAM22,P2RY13,NELL2,NF1,DNHD1,IGSF11,OLR1,SNTG1,CNTN3,DPY19L2P2,PDE4B,PDGFRA,GNG2,BEST3,CDK14,TMIE,PIK3R1,CCSER2,ZFYVE21,PLIN1,HMGCLL1,STRN3,ING3,POU6F1,PPM1B,PPP2R5E,PPP3CA,RANBP3L,PRKACB,MAPK10,SAMD9,PXK,PTN,TMEM260,PTPRG,C1orf109,PEX2,PID1,CEP97,RAD51D,RAP1GDS1,ZNF493,OXR1,RASGRF2,ARID4A,KHDRBS2,MSANTD2,PRIMA1,PBRM1,RNASEL,RPRD1A,RAVER2,CARF,ROBO2,RPE65,NEK11,GLDN,PRR5L,ADAL,TRAPPC13,AP1AR,SATB1,SCN3A,SLC30A10,SUPT20H,SCAF8,CPEB3,FBXO11,ST6GAL1,CNKSR2,ANKRD6,ZNF365,BTBD3,KANSL3,SLC8A3,TET1,DMRTC1,MYH15,SMARCE1,RCOR3,LIMCH1,SNCB,UNC80,USP33,PDZD2,TRERF1,SOX2,SOX5,NPAS3,CLSTN2,ITPRID2,STOX1,MPRIP,STAU1,KANK1,FGD4,ANKRD28,CAMTA1,EHBP1,ZFP90,ZEB1,TRIM2,SYNE1,NSD1,ARHGEF12,PCDHA5,CCDC173,PMS2CL,KHDC1,ZFPM2,AKTIP,SLC44A1,TIAM1,MTMR14,TIE1,TLR4,ERCC6L2,FAM124A,C5orf64,RBFOX2,NPL,TRIO,ANO5,SGK3,CADM1,EIF4ENIF1,SLAIN1,USP1,ZNF709,CCDC14,VLDLR,VSNL1,LAT2,ZNF708,KCNT2,TRIM9,CELF4,ZNF189,ANKS1B,EMSY,PRTFDC1,RNF103,TMEM163,CAB39L,WNK3,EPM2A,RTN4,NUP214,SSPN,NETO1" MicroRNA hsa-miR-567:mirSVR_lowEffct hsa-miR-567:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-138 2.88E-134 8.08E-137 7.44E-136 384 1733 "SYN3,CLK4,KLHL32,ADCY8,ADD3,PWWP2A,ESYT2,KIDINS220,BEND6,MTA3,SLC44A5,GPR158,KLHL13,OSBPL6,BCAR3,FAM135A,MRTFA,ANK2,SEMA7A,EP400,CCDC146,PHF12,ANXA7,UPRT,CPNE5,CASK,TMEFF1,MARK4,NCOA1,TMEM108,ATM,SLC4A4,ATP2B1,B3GALT2,ATP6V0A1,RIPK1,BBS2,MPDZ,BCHE,RGS11,BID,BMPR1B,SGCE,CACNB4,DIRAS1,CAMK2G,TRIM41,CH25H,SPAG9,CERS5,CCNH,ARHGEF2,NUMBL,CACNA2D2,SRSF11,SOCS6,NDST3,HECTD1,NIPBL,COL4A5,SLC25A27,ABI3BP,BAG4,ZFP28,CP,SEC31B,CLOCK,CREM,GDA,LRRC3B,PDE4DIP,CNTNAP2,SLITRK5,PLCXD3,RIMS2,HDAC9,MYADM,ZNF337,TBC1D5,DGKB,ARMCX2,JAKMIP2,C8orf34,ZEB2,HP1BP3,CEP170,BLOC1S6,CHRDL1,GRIN3A,RAB39B,CDON,SLC12A6,DYRK1A,SNX29,KLHL5,YAF2,FAM13A,PHF20L1,ABI2,EIF5,ELAVL4,RGS17,PAN3,LRRC17,RABEPK,SRRM1,EPS8,ZNF549,ETV1,KATNAL1,F3,F5,F8,CACNG2,SCML2,CEP78,FKTN,FECH,SLC9B2,OLFM1,POLR1B,FGF13,MEX3B,SEC23B,IP6K2,SYNCRIP,RGPD5,ANKFY1,SLC37A3,C2orf88,PDLIM5,ATP6V1H,KHDRBS3,DKK3,CHL1,GABRB1,CAB39,GAD1,GAD2,JPH4,ERAP1,ARFIP1,ADAM28,FREM1,TCERG1,GLI2,KIAA1958,DCLK2,GNAO1,NUDT21,PCLO,GRIA1,DIDO1,BTN2A1,RNF165,TMEM25,GSTM5,LINGO1,GUCY1A2,GUCY1B1,MAP4K5,FRMD3,BACH2,AGBL5,ZDHHC15,TCEAL6,DHX35,HTR5A,ZNF546,LRRCC1,BRINP3,ZNF385B,OLFM3,KCNC2,KCND2,KCNJ3,KCNJ10,KCNMA1,LAMP2,STMN1,C1orf194,MAP4,MATN3,IL17D,CHIC1,TM6SF1,SHC3,MEIS1,SCAMP5,MMP16,ERICH3,COMMD5,BLOC1S2,ADAM22,MSRA,SCG3,CTNNA3,MYO9A,NAP1L2,NAP1L3,NELL1,SLCO1C1,CNOT4,NTRK2,GPR137C,CNTN3,DPY19L2P2,PDE1A,PDYN,PFKFB2,SSH1,NALCN,ZNF655,FAM216A,PCDH18,HMGCLL1,PURG,PMP2,PMP22,EXOSC10,ING3,FA2H,PPM1B,PPP2R2B,LRRN3,CRLS1,PPP2R5C,PPP3CB,KANSL1,PRKAB2,CNNM2,SNRK,PIGG,CNTLN,BDNF-AS,PTHLH,PTN,PTPRG,PTPRH,PTX3,ACSM5,USP47,ATG16L1,ZNF493,BSDC1,ZMAT4,REV3L,MORC4,GTDC1,UBR7,RGS10,PRIMA1,RIT2,SLC25A36,RIC8B,PBRM1,RPRD1A,ZFHX4,RPE,NEK11,ZNF671,MCMBP,GLDN,ACER3,LRRK2,MEG3,ABCA11P,HSD11B1L,KCNIP3,SEMA6D,SCN4B,LRRTM4,ZFP2,TRA2B,SCAF8,ARX,FERMT1,CPEB3,DOCK10,FNDC3A,R3HDM2,ZNF365,PEX26,PPP4R3A,DHX30,ZNF430,SLC14A1,CPEB4,ZFP1,ZNF667,SORCS3,LIMCH1,MBD5,UNC80,DOP1A,BDP1,MYCBP2,KIF1B,RBM26,NPAS3,SPART,C11orf87,PBLD,CLASP2,ITPRID2,SAMSN1,SSTR1,ZC4H2,LRRC4,SS18,STAU1,ELOVL4,RGL1,SULF2,NECAB1,SYT11,ARHGEF9,TACC1,FAM208A,KIAA1107,TBCEL,ANO4,ACSL6,SATB2,WASHC4,PCDHB15,RALYL,SLC19A3,ARHGEF12,C18orf54,LEFTY2,DDHD1,TLR4,HEY2,KAT6B,TPM3,RUNDC3B,STXBP4,ZMYND8,SSBP2,TTTY15,TUB,ZNF610,MEAF6,WIPF1,NSD2,XRCC4,PCDH20,ZNF17,ZNF24,MICU3,LYPD6,CELF4,ZBTB38,REEP1,FSTL5,SPIRE1,PLPPR5,WNK1,EMSY,PRDM2,LRP8,CSDE1,EVI5,ADAMTS9,MDH1B,NAV3,NAV2,SLC17A6,EPM2A,DOCK8,PAK5,KAT6A,SMIM8,TIGD6,RNF170,VANGL2,SLC39A12,IFT88,NETO2,NETO1,SOCS4,GAN,ZNF30" MicroRNA hsa-miR-31:mirSVR_lowEffct hsa-miR-31:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.34E-138 3.56E-134 9.94E-137 9.16E-136 388 1769 "VWA5B2,ABR,ACADM,ACHE,CSMD2,CSMD3,ADCY6,UNC5A,KIAA1211,AP2A2,INTS2,TBC1D14,KIAA1324,CC2D2A,AK2,ARHGAP20,PCDH10,UNC79,PDZD4,AMT,ZFAT,OGT,PI16,CCDC146,LCORL,PRX,MADD,SPTBN4,STK33,CCDC74A,CAPRIN2,ASPH,SLC2A11,MTMR9,SNAI3-AS1,KSR1,SYNJ2,SCAPER,C1QC,OSGIN2,BTRC,CACNA1E,CACNB2,CALM1,CAMK2G,VXN,SYT6,VSTM2A,HIP1R,CERS5,USP2,ENTPD2,CD81,LRBA,CDC42,DCLK1,LARGE1,SOCS6,CASC2,NDST3,DLGAP3,KIAA1549L,CLTA,FADS2,HECTD1,FHL5,SUMF2,COL9A1,BTF3L4,COX4I1,SMARCAL1,ZNF521,CREM,NCOR2,ARHGEF10,CSNK1E,ATRNL1,CHD5,FAM169A,DZIP3,ERC2,CFAP61,RUBCN,CX3CR1,MYADM,CENPL,KIF26A,RIMS3,MAML1,TMEM170A,BRINP1,ARMCX4,YTHDC1,ZBTB24,FBXL5,COPS7A,MAGI2,DDX46,SRGAP3,NTM,WDR20,DMD,CPEB2,DMTF1,SLC12A6,DNM1L,E2F5,EDNRA,SYT15,HEYL,SIDT2,EIF5,ELAVL2,PLEKHA1,C3orf18,EPB41,ENPP6,GPHN,SLC43A2,SPEG,CDHR1,MRPL37,TMEM74,MRPL10,VPS26C,F8,WAC,FABP7,ZIC4,TAOK3,ATP8A1,STRADA,SLC9B2,SUCO,UBE2E3,SEC23B,FOXF2,IP6K2,ANKFY1,NOP56,C2orf88,FAM49B,CELF1,DACH2,CGREF1,STAU2,NRG3,GABRB1,SALL3,NEK6,GAP43,ERAP1,SEPT9,INPP5K,KIAA1841,GCK,ADAM28,TXNL4A,PCDH11X,STARD3,MAP7D2,GNAO1,GPT2,WDFY3-AS2,PRRC2B,GPD1,GPM6B,STON1,NUDT21,GRB10,GRIA2,DIDO1,GRIA4,KIF3A,GSTM5,GSTT2,AP4S1,RNFT2,ATOH8,MUM1,ATG4C,PADI2,ZHX1,ATXN2L,HLF,SYNPO,OPALIN,ICA1,LINC00667,GAREM2,KCNA2,OLFM3,KCNC2,KCNN2,KCNN3,LINC00634,STXBP5,KTN1,CAMK2N2,STMN1,INSYN2,LIFR,FGFBP3,MAP2,MAP6,MARK1,MAT2A,MEIS2,PPM1L,MMP16,ERICH3,DBNL,ADAM22,PTOV1,MT1M,MYL3,NBL1,NEK1,NTRK2,NTRK3,OGG1,PCDH8,PCDH9,SEMA5B,CAMKV,ANLN,FAM216A,PLP1,PMP22,TRHDE,CDIP1,STRN3,PRRX1,RETREG2,FA2H,PPP1R1A,PPP2R5C,PPP3CA,PPP3CB,PRKAB2,PRKAR1B,PRKCG,MAPK10,GRAMD1C,SIDT1,PSMD13,CNTLN,ANKHD1,PLPPR1,UHRF1BP1,TMEM260,ZSCAN32,EML5,PTPRE,PTPRG,FAM120C,PEX2,TMEM231,ATG16L1,OXR1,RASGRF1,RASGRF2,ARID4A,FEZF2,RBBP6,ZDHHC14,RDX,SLC6A15,ZYG11B,TRIM68,SLC25A36,MYH14,KIRREL1,SNX22,EMID1,LGR4,SYNDIG1,SOX8,KCNIP3,WLS,S100B,LINC00461,SCP2,FOXRED1,SFPQ,NLGN4Y,SGK1,SH3GL2,SH3GL3,HKDC1,AMBRA1,CCDC92,SLA,PEX26,LIMS2,LRRC55,SLC6A9,TRIM67,SLC11A1,SLC15A2,SPHKAP,SLN,SORCS3,CDK5RAP2,INAVA,SNRPN,PALLD,RBM34,SCN3B,WDTC1,SOX11,MYCBP2,ZC3H13,SPTAN1,IQSEC2,SPART,NFASC,ATP10B,ITPRID2,MPRIP,TTBK2,RGL1,ADHFE1,STX1A,SEPT3,SYT11,MLC1,RHBDL3,PLCB1,SYN2,TACC1,TAL1,VWA3A,SIN3B,DMXL2,TCF7,NAT16,TMEM151B,PUM2,ITGB3BP,TGFBR3,ARL10,TJP1,DDHD1,ERCC6L2,PRRT1,C5orf64,RBFOX2,TPM4,CHST5,RGMB,RUNDC3B,NEIL2,RUSC1,TSC1,TTTY15,HSPBP1,CLHC1,AMOT,PLEKHH2,TBC1D15,WRN,CLDND1,GUSBP1,PCDH20,ZBTB14,PLPP4,TCEAL7,POLR3H,DPYSL5,SLC30A3,PRDM2,CSDE1,STOX2,LMAN2L,RNF103,TMEM178A,LINC00632,CAB39L,MVB12B,AMN1,DOCK8,RTN4,CERS6,SSPN,FXR1,LAS1L,SPATA13" MicroRNA hsa-miR-4295:mirSVR_highEffct hsa-miR-4295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.24E-138 4.63E-134 1.29E-136 1.19E-135 314 1164 "CLK4,NCKAP5,CSMD3,ADCY6,CCDC85A,GALNT13,AXIN2,SLC12A5,PLEKHH1,KIAA1211,BEND6,GPR158,HECW2,OSBPL1A,WDR35,HFM1,ALCAM,SRPX,ABCD2,FAM135A,MRTFA,LRCH2,LCORL,USP28,APAF1,APC,API5,AQP4,MIER1,LINC00173,STK33,CAPRIN2,NCOA1,STX16,ATP2B1,ZNF583,NOL4,ADAM23,TTLL9,TTC9B,ADGRB3,NRP2,DST,C5,THSD7A,KALRN,SYT6,CAST,MAP7,RUNX1T1,USP6,TIGD7,CFL2,CHN2,SYNPR,KMT2C,ZFYVE9,PLAA,KIAA1549L,CLTC,NIPBL,AKAP7,ARMC8,FAM149A,BTF3L4,ACBD5,HS3ST5,CLOCK,CREM,GDA,CSF1,LRIG1,SIPA1L1,CHD5,SOCS5,PDE4DIP,PITPNM3,APPL1,PHF14,GREB1,ARHGEF4,NRSN1,PPP6R2,ST18,CCDC144A,CYBB,BOC,DCAF8,ZFYVE16,LONRF1,SPATA2,ZEB2,FBXL5,KIAA0319,CEP170,RHOBTB1,SPOCK3,WDR20,DPYSL2,ABCC5,ABCC9,GOLT1B,AASDH,WDPCP,EDN1,FAM13A,KMT5B,EGR3,CERCAM,PAN3,ENPP6,SRRM1,RASL12,F3,WAC,ACSL4,TESK2,GORAB,MED12L,PRKAG2,SEC23B,FOXF2,SYNCRIP,RGPD5,NBEA,TPK1,NPTN,GABRA1,HBS1L,B4GALNT1,GAP43,ERAP1,MYOZ2,ARFIP1,SESN1,ADAM28,RAB30,GLS,TNRC6A,MSL3,KDM2B,MAP7D2,INSM2,RAB40B,PRUNE2,RAPGEF4,GRB10,GRM7,CIT,LINC00839,RNF165,BACH2,HMGB1,IRF8,ZIC5,LRRCC1,ZNF678,KCNN3,CREG2,LIG4,ARHGAP12,NCOA7,MAP4,MATN3,MBNL1,MDM4,LRP1B,MOG,ERICH3,BCO1,MTR,LYRM9,ZNF862,MYT1,NAP1L3,NELL2,NEUROD1,CNOT4,NTRK2,OCRL,OMG,OPHN1,LOC100128398,PBX1,PCSK5,PDE1C,PDE3B,PDGFRA,CCSER2,ST8SIA5,JAKMIP1,PURG,LRP12,SCHIP1,POU3F2,CRLS1,GRAMD1C,PSD,PLPPR1,MTMR10,PTHLH,PTPRG,RAB5B,PID1,CEP97,ATG16L1,RASGRF2,RBBP8,KHDRBS2,ZDHHC14,RET,ERI2,SLC25A36,RPRD1A,KLHDC8A,CARF,ROBO2,EPHA10,ATP8B4,LRRK2,CNTNAP3,CLIP1,RTN1,LRFN5,SCN3A,FAM19A1,TNFRSF19,PEAR1,ARX,KIF16B,NTNG1,CHD9,SLITRK3,SYBU,SEC31A,BTBD3,WDR47,RUFY2,SEPHS1,SLC8A1,CCDC88A,SHANK2,BTBD7,NAXD,SNAP25,KIF13A,USP33,MYT1L,TRERF1,SOX5,DOK5,TEX2,ZC3H13,CDK19,SPART,TROVE2,CLSTN2,POGZ,SMOC1,NKAIN2,ERBIN,MPRIP,GSE1,ZFR2,NUDT10,PLCB1,SYN2,ANKRD12,MTCL1,CAMTA1,CAMSAP2,FBXW11,ZEB1,PCDHB4,TEK,DICER1,ZFPM2,ITGB3BP,SLC44A1,ZFP91,ERCC6L2,R3HDM1,CSMD1,TNS1,TRPC3,TSC1,UBC,FAM155A,AMOT,SLAIN1,CCDC14,WRN,ZNF711,ZNF74,SPHK2,ZBTB38,REEP1,FSTL5,WNK1,PMEPA1,MAP3K12,MFF,LRP8,STOX2,CAB39L,WNK3,PLSCR4,C12orf4,RGS7BP,UBE3B,NHSL1,SLC39A12,FXR1,FRMD6" MicroRNA hsa-miR-4314:mirSVR_lowEffct hsa-miR-4314:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-137 5.94E-134 1.65E-136 1.52E-135 399 1869 "CPNE2,EMILIN3,SYS1,GPRIN1,XKR4,NDRG3,ADARB2,TMEM132B,ADORA1,ADORA2A,PWWP2A,RNF150,KIDINS220,BEND6,SNX32,ALAD,CEP126,FAM135A,SYT13,KIF6,CDC42BPA,PI16,CNIH2,PPFIA1,SHTN1,AQP4,KIAA1614,MADD,IGDCC4,ARHGAP5,PLA2G4C,LINC00173,NUMB,ATP2A2,DPY19L3,DNAJC27-AS1,KSR1,BMPR1B,ST3GAL5,AP1M1,CACNA1G,RAB29,CACNA1D,LURAP1,NGB,TRIM41,CANX,VXN,SPAG9,ENTPD6,KCNAB3,LRRFIP1,LGI1,L3MBTL4,LARGE1,DLGAP2,NOG,DLGAP3,RAB33A,COG1,C4orf33,QKI,TMEM155,CNTN1,WHRN,LETMD1,COL11A2,SMARCAL1,CRY2,CRYBB1,GDA,CRYM,SNCAIP,RGS6,ARHGEF10,OSBPL3,SUSD5,PDE4DIP,SLITRK5,SDC3,KIAA0040,CTNND2,EDRF1,SEC14L5,NOS1AP,CYBB,ARHGAP32,TCAF1,PHF19,ZNF337,DAPK1,SCRN1,GIT2,SIRPA,PITPNC1,ZBTB24,RUSC2,BLOC1S6,ALKBH8,RHOBTB1,MTX3,WDR20,DLG2,DLG3,DMPK,USP3,DOCK2,DMTF1,DRD1,RCAN1,DTNB,FAM78B,DNAJB6,DNM1L,EBF1,EDNRA,SEMA3D,TMTC1,SIDT2,EFNB3,APH1A,EGFR,MRO,GOLGA7,ASB3,DCTN4,EMX2,EPHB1,ERBB2,PIPOX,DNAJC27,CEND1,ADGRV1,F8,ZNF461,TUBA1B,ST3GAL6,TESK2,OLFM1,UBE2E3,HPCAL4,ANKFY1,SLC37A3,FOLR2,COQ5,TRIM16,ZNF605,CELF1,B3GAT1,TPPP3,NRG3,NEURL4,GABRA5,CHL1,NCKAP1,TMEM8B,DISC1,SEPT9,ATP8A2,INPP5K,ACSS1,MYOZ2,ARFIP1,CYP46A1,GFAP,GGT7,GGT5,TTBK1,COPS8,POLL,PRRC2B,PRUNE2,CCDC184,GRIA4,ADAMTS13,GRM3,GRM7,LINC00839,RNF165,ZBTB49,PSIP1,SLC2A6,IRAK3,NXPH2,ATXN2L,HPSE2,SYNPO,AGBL5,HPCA,HSD17B1,LINC00667,ZIC5,DISP2,SCIN,LRRTM1,ITPKA,ITPKB,METTL21A,L1CAM,LMO2,SYTL4,VWA5A,NCOA7,LSS,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SYT9,ADAM11,MEIS1,MEST,KITLG,PPM1L,AFF1,MOBP,MPP2,COL28A1,CTNNA3,HS6ST3,MYBPC1,LYRM9,MYO6,MYO7A,HNRNPM,NCAM1,CNOT4,SLC11A2,NRGN,OLR1,OPCML,OPHN1,PDE3B,PDE1B,PDGFRA,GPR85,SERPINI1,XRN1,PLCL1,PLP1,SLC25A23,PMP22,LRP12,EXOSC10,FA2H,C19orf57,DRAM2,TMEM235,PCDHB17P,CRLS1,PPP2R5E,PRKAB2,PKIA,HYDIN,MASP1,WBP1L,SIDT1,PTCH1,ANKHD1,UHRF1BP1,ELOVL2,PXK,TMEM260,C1orf109,ZSCAN2,PPP2R3C,SH3TC2,RASGRF1,RASGRF2,BSDC1,ZYG11B,ZMAT4,TRIM68,RET,GTDC1,UBR7,CARF,NEK11,MCMBP,RPS6KA2,ST6GALNAC6,ZNF331,DGLUCY,FOXRED2,SEMA6D,HOGA1,PRCD,SEC14L1,GALNT10,MRAS,SUPT20H,SCAF8,MAGI3,FBXO11,FNDC3A,CTXN2,WDR37,PPP4R3A,EPN2,SLC11A1,SCMH1,SORCS3,LIMCH1,MBD5,TMCC1,UNC80,PDZD2,SOX5,BDP1,NMNAT2,GLT8D1,ZNF423,SPTAN1,NPAS3,COLGALT2,SSTR1,ST5,ZSCAN29,CEP68,STX1A,SEPT3,AJAP1,FAM168A,JMJD6,NUDT10,PLCB1,ARC,TACC1,TAL1,AGTPBP1,TBL1X,KLHL4,ANO4,TBX15,VWC2,SATB2,TPCN2,TCF12,CLASP1,SZT2,AZIN2,DOCK9,USP32P1,HIF3A,RNF175,ZNF106,HHIP,GALNT17,TLR4,TMPO,FAM124A,BEX4,C5orf64,PIK3R5,TP53BP2,SEZ6L,CDK20,TPM3,ZNF384,SYNPO2,PDSS1,TSC1,ANO5,RFTN2,LINC00689,UGT8,MEAF6,LAT2,WRN,RICTOR,XRCC4,TRIM9,ZBTB38,TMEM237,ZNF189,ZNF213,UPF3A,INTS3,PRDM2,NT5M,STOX2,GAL3ST3,NAV3,NAV2,PPP1R3F,CAB39L,TRIM16L,WIPF2,MVB12B,RGS7BP,ST7,PHTF2,CASC15,NUP214,ZNF248,RNF170,TTC7A,SOCS4" MicroRNA hsa-miR-363:mirSVR_lowEffct hsa-miR-363:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-137 6.08E-134 1.68E-136 1.55E-135 377 1676 "VWA5B2,AS3MT,ADARB2,ELFN2,CCDC85A,ADD2,ADD3,PWWP2A,BEND6,MTA3,GPR158,HACE1,OSBPL8,BCAR3,PCDH10,UNC79,AMPH,LRCH2,ANK2,PPFIA2,PKP4,ANXA7,APBB2,MAGEE2,DDO,AQP4,PPP4R4,CASK,RGS20,CDK13,DACT3,ZBTB10,NCOA1,ASTN1,ATP1B3,ZNF582,N4BP2L1,NOL4,BACH1,SNAI3-AS1,FUBP1,BSN,BTRC,VXN,VSTM2A,SLC16A4,TMEM257,REPS2,CDC42,LGI1,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,AKAP7,PCYT1B,ARMC8,COL9A1,BTF3L4,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,CHD1L,SLC35F1,SEC31B,C2CD2,CREM,AKAP12,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,CX3CR1,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,SIRPA,DCC,DNAJC6,HP1BP3,KIAA0753,DDX46,SNAP91,SRGAP3,NTM,WDR20,DLG2,NR1D2,ABI1,MAMLD1,EDIL3,EFNB3,FAM13A,ABI2,EIF4G2,SORBS3,TENM1,EML1,STARD3NL,EIF1,EMX2,EPHA5,KCNMB2,EPS8,ERBB4,MRPL37,DNAJC27,CLVS1,ZIC4,SCML2,DLC1,RACK1,ST3GAL6,CEP78,FKTN,TESK2,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXG1,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,STAG2,MEGF11,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,SIGLEC8,MTHFD2,LRRC37A6P,KIAA1841,GATM,CRCP,DBF4,GLS,ZNF638,PRRC2B,GPM6B,FUT10,STON1,EML4,GRIA4,GRIK2,GRM8,GSTT2,LINC01551,SOX21,GUCY1B1,IRAK3,ZHX1,HMGCR,LRRC75A,EID2B,FAM95B1,C5orf24,LRRC25,INSM1,ZNF385B,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNMA1,KIF5C,KLC1,IPO5,INSYN2,PAXBP1,HECTD2,FGFBP3,NCOA7,PACRG,C1orf194,MAP4,MARK3,TM6SF1,MEIS1,PPM1L,AFF1,MMP16,MYH3,BEX5,NAP1L2,NEK1,NELL2,NEUROD1,NFIA,NFIX,NKX2-2,CNOT4,NPY,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PIRT,PDGFRA,PDYN,PFKFB4,OLA1,CDK14,XRN1,FAM216A,PLP1,PCDH18,PMP22,SPATA6,EPB41L4B,PPARA,PPM1B,CRLS1,PPP2R5C,PPP2R5E,RANBP3L,PRKACB,PRKCG,PKN2,EPDR1,DCHS2,LAMA1,SIDT1,MDGA2,CNTLN,PTHLH,OCIAD1,PTPRG,PEX2,STRC,MARCH1,SLC25A48,USP47,RAD51D,SH3TC2,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,GTDC1,RLBP1,SLC25A36,ZFHX4,RERGL,ELP2,ACER3,STK32B,LRRK2,RPS20,SYNDIG1,RYR3,ZNF331,CCDC112,FAM192A,MIR124-2HG,SEMA6D,CSRNP3,ATXN7,SCN2A,LINC00461,RASA3,NLGN4Y,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,FBXO11,SYBU,ZNF365,FAM81A,SLC6A1,SEPHS1,ATF7IP,SORCS3,LMBRD1,MYT1L,SOX11,DOK5,ENKUR,HECW1,ZNF423,CDK19,MCF2L2,RBM26,SRPK2,TAB2,ATP10B,EPB41L3,ZC4H2,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,ANKRD12,MTCL1,DDHD2,UNC5D,KLHL4,TBX15,ATMIN,DMXL2,ZEB1,NAT16,RALYL,TEK,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TMOD1,CSMD1,TPD52,TPM1,METTL3,PRMT8,PDSS1,STXBP4,TSC1,SSBP2,PITPNB,PLEKHH2,XRCC4,ZNF28,TRIM9,ELFN1,SPHK2,REEP1,MEIS3,PMEPA1,ZXDA,PRDM2,TMEM178A,SNX27,C12orf4,FZD3,KAT6A,FBXO36,JMJD1C,MSRB3,NETO1,FAM198A,SENP7" MicroRNA hsa-miR-4330:mirSVR_lowEffct hsa-miR-4330:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-137 6.20E-134 1.71E-136 1.58E-135 387 1763 "TTYH1,ACADM,ACLY,CLK4,SYS1,FMNL2,KLHL32,ADCY6,RNF157,ADD2,ADD3,ADORA2A,KIAA1211,ESYT2,KIDINS220,BEND6,OSBPL1A,WDR35,OSBPL8,CC2D2A,C1QTNF3,LRRC7,BCAR3,ARHGAP20,FAM135A,ANK1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APC,VAT1L,API5,AQP4,CDK10,ARNTL,NCOA1,ALDH4A1,ATM,ATP1A2,ZNF582,RNF182,ADGRB3,SEC11C,ZNF599,KSR1,SYNJ2,ARHGEF7,CASTOR3,MTMR3,GYG2,CALB1,DIRAS1,CAMK2B,SYT6,CH25H,SPAG9,ARHGEF25,CBS,USP6,MTMR7,AP4M1,CDC27,CDH8,DCLK1,ARHGAP33,CDH18,MAGI1,RCBTB2,SRSF11,SOCS6,CASC2,JAM2,NDST3,NRXN3,CLTA,NGEF,FBXO7,ABCG2,NIPBL,CNR1,CNTN1,AKAP7,ARMC8,AKAP6,WHRN,COL4A5,SUMF2,MYRIP,RBM39,CREB5,CRY2,ANKRD44,LRRC3B,MICAL2,CHD5,PHACTR3,CST3,NRSN1,PUM1,DCAF4,EDRF1,CYBB,FRMPD4,ZFYVE16,EARS2,RIMS3,DGKB,SPOCK2,DBI,AIF1L,GIT2,ARMCX4,ZEB2,COPS7A,GSDME,RHOBTB1,SRGAP3,FAM107B,NR1D2,DNM2,DMTF1,PDCD6IP,FAM78B,MAMLD1,ABCC9,KRBA2,SEMA3D,TMTC1,CELSR3,MBNL2,ABI2,LPAR6,GOLGA7,EIF5,IRAK4,STARD3NL,EIF1,EN2,EPB41,EPB41L1,KCNMB2,ANKRD13B,ERBB4,DENND4A,DUSP27,DNAJC27,RCSD1,GMPR2,CLVS1,FABP7,TMEM132C,FCGRT,SUCO,UBE2E3,PCYOX1,ANKFY1,HVCN1,ZNF605,KHDRBS3,NSG2,CELF1,ADGRA1,MSANTD4,DOT1L,ABLIM2,ZNF512,GABRA1,BRPF3,B4GALNT1,ARPP21,ZNF274,ERAP1,TMEM8B,KIAA1841,GATM,IGSF5,ALDH1L1,MSTN,ARFIP1,ADAM28,DHRS4,HPGDS,PCDH11X,GNAS,ADGRA3,LILRA1,STON1,NUDT21,PCLO,GRIA4,GRID1,SERP2,FAM19A2,RNF165,RABL2A,WIF1,ATG4C,HMGB1,SYNPO,AGBL5,LRRC25,NKD1,LRRCC1,IL6ST,JAK2,KLRC2,A1BG-AS1,IPO5,SFXN5,MAG,PIK3AP1,MAP4,CHIC1,MEIS1,MOBP,CD200,COL28A1,C10orf105,HS6ST3,LYRM9,MYO7A,NAP1L3,NCAM1,NELL2,OTOGL,ALDH1L2,OCRL,CHAMP1,OPA1,OPCML,OPHN1,ZNF713,PAH,SNTG1,PAK3,PCDH9,PCSK5,PDE2A,PDE3B,PIRT,BEST3,ZNF655,A2ML1,CCSER2,ST8SIA5,PLCL1,SMIM7,HMGCLL1,ANKRD16,PPM1B,PPP3CB,GON4L,MDGA2,ANKHD1,UHRF1BP1,PXK,PTPRN2,PEX2,STRC,RAB5B,TMEM255A,SH3TC2,FAM184A,OXR1,RADX,GTDC1,SEC61A2,ZFHX4,CCDC82,SETD5,ALG9,CCDC102B,FBXW7,GLDN,FAM161B,ABCA11P,ST6GALNAC6,KCNIP2,SBF1,CSRNP3,SCN2A,LINC00461,ASIC4,FOXRED1,MRAS,SCAF8,FRMPD1,NTNG1,FBXO11,ANKRD6,ABLIM3,PEX26,PPP4R3A,EPN2,KANSL3,KDM4D,RAB3GAP1,ARHGEF40,CCDC88A,SLC12A2,ELMO2,SLC20A2,SORCS3,SMARCD3,RCOR3,RIMS1,MBD5,CMTR2,SNRPN,UNC80,BDP1,FNBP1,ZNF423,TSPYL2,CLASP2,SAMSN1,SS18,NXT2,STAU1,ADHFE1,AJAP1,MLC1,FGD4,SUPT5H,SYNE2,PLCB1,SYN2,SYP,SYT1,SEMA4A,DDHD2,TAF9,FAM208A,UNC5D,TMEM136,ANO4,ATMIN,TCF4,DOCK9,PCDHB4,USP32P1,FAM200B,CRB1,LEFTY2,ZNF106,SLC44A1,HEY1,ZFP91,KCTD2,PIK3R5,RBFOX2,TPM3,RGMB,TRIO,TRO,PPIL6,ANKRD20A2,AMOT,LINC00689,OSBP2,BCL2L13,MEAF6,LAT2,NSD2,CLDND1,ZNF711,ZNF24,ZNF32,KCNT2,LAMP5,EMSY,PRDM2,RNF103,NAV3,KCNAB1,FAM47E,FZD3,DOCK8,KAT6A,HNRNPA3,FBXO36,CASC15,ZNF248,VANGL2,ST8SIA2,SLC4A10,CPNE4,SENP7" MicroRNA hsa-miR-657:mirSVR_lowEffct hsa-miR-657:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.17E-137 6.55E-134 1.81E-136 1.66E-135 353 1474 "CPNE2,SERPINA3,DGCR6,METAP1D,FAM43B,ARID1A,KLHL32,RNF157,SLC12A5,SORCS1,USP31,ADORA3,AP2A2,OSBPL1A,CC2D2A,AK2,SMIM17,SEMA6A,ALCAM,LTBP4,FAM135A,EPB41L5,ALS2,CACHD1,TNRC6C,ARSE,CDK13,ASCL1,ASPH,ASTN1,ATP1A2,SLC4A4,N4BP2L1,DPY19L3,ADAM23,BCL7A,KSR1,BMP7,ARHGEF7,AP1M1,CACNB4,THSD7A,KALRN,PTBP2,CAMK2A,VSTM2A,CH25H,RUNX1T1,RGN,CDK11B,CDC27,CDH8,LGI1,MAGI1,DLGAP1,CFL2,SRSF11,SOCS6,CHM,CHN1,RAB3C,RAB33A,NRXN3,CLCN4,NRXN1,CLTC,CNR1,PCYT1B,ARMC8,SLC25A27,ZNF521,C2CD2,CRY2,ANKRD44,NCOR1,CS,MROH8,CSF1,RGS6,CSF2RA,FEZ1,MICAL2,OSBPL3,SIPA1L1,CHD5,NCAN,APPL1,PUM1,ST18,DCAF4,RUBCN,CX3CR1,ECE2,MATR3,KIAA0586,DGKB,GIT2,ARMCX4,PITPNC1,ARMCX2,ZEB2,B3GAT3,KLHL3,SRGAP3,RABGAP1L,KIF19,GNE,DTNA,AASDH,EDNRA,ANKRD46,HEYL,RASA4,EIF5,ELAVL2,PCOLCE2,DCTN4,EPB41,SEZ6,EPHA5,ERBB2,NCALD,CDHR1,ETV1,RRAGB,EXTL2,ECSIT,F5,CLVS1,NSRP1,WAC,FGF11,SUCO,SLC37A3,NELFCD,KHDRBS3,CELF1,CSPG5,PNMA2,SARAF,CAB39,BRPF3,NCKAP1,SULT1C4,SESN1,COPS8,GLDC,GLI2,ZNF638,GPD2,PRUNE2,TDRKH,LPAR4,PCLO,GRIA1,GRIA2,RFFL,GRM7,BTN2A1,COQ10A,TMEM25,GSTM5,BVES,AP4S1,SOX21,LINGO1,FAM107A,SLC2A6,GYG1,HAS2,TOX2,PACSIN2,FRMD3,HAPLN2,TCEAL6,MSL1,FAM95B1,MYLK2,DOCK7,ZNF385B,KCNA4,KCNA6,KCND2,GATD1,KIF5C,KIT,STXBP5,L1CAM,LAMP2,NCOA7,SMAD1,PIK3AP1,MAP4,MAPT,MATN2,MBNL1,MBP,LDLRAD3,MID1,AFDN,MOBP,BLOC1S2,PTOV1,N6AMT1,MTR,HNRNPM,NAP1L1,NDUFA5,NHLH1,NME4,CNOT4,SLC11A2,NUCB2,LOC100128398,OPRL1,PCDH8,PDE3B,PDGFRA,PFKFB2,PFKFB3,ZNF655,FAM218A,FTO,PLXNB3,STRN3,LRP12,RETREG2,EPB41L4B,MINDY2,PPM1B,RASGEF1B,PRKACB,PKIA,PRPSAP2,CNNM2,NDUFS7,BCAS3,VPS13C,SIDT1,MDGA2,BDNF-AS,PTK2,PTPRO,TMEM255A,KHDRBS2,ZDHHC14,TRIM68,GTDC1,PBRM1,ZFHX4,SETD5,C12orf49,GSTCD,CCDC102B,NEK11,ARMH4,GLDN,RIMKLA,LGR4,WLS,DGLUCY,ATXN7,SCN3A,LINC00461,TNFRSF19,GALNT10,SUPT20H,KIF27,TRA2B,FBXO11,SLITRK3,PEX26,PPP4R3A,KANSL3,RAB3GAP1,SHANK2,SLC15A2,LGI3,CPEB4,SMARCC2,SORCS3,ANKRD36,MBD5,TMCC1,MYO16,FNBP1,ERC1,KIF1B,LHPP,SAMSN1,EPB41L3,MAPK8IP3,CEP68,VPS13A,SYT1,ANKRD28,TAC1,SEMA4A,PJA1,CAMTA1,MLST8,WWC1,AGTPBP1,IQCE,VWA3A,TPCN2,TCF12,SZT2,SYNE1,FAM189A1,SIRT1,ZFPM2,ARL10,PRRT1,TPD52L2,TPM1,SMUG1,TRIO,TRO,TRPC3,TRPS1,CLHC1,RPL7L1,UBE2H,UGT8,SLAIN1,PLPPR2,VAV2,BEST1,WIPF1,ZNF24,FMN2,REEP1,FSTL5,ZNF189,SPIRE1,CA10,EMSY,CADM2,XKR7,MDH1B,URM1,SLC17A7,SNX27,WIPF2,GOPC,DNAH10,RTN4,CASC15,ZNF248,IFT88,SOCS4,ST8SIA2" MicroRNA hsa-miR-92a:mirSVR_lowEffct hsa-miR-92a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.39E-137 7.80E-134 2.14E-136 1.98E-135 375 1660 "VWA5B2,RBM10,AS3MT,ADARB2,ELFN2,CCDC85A,ADD3,PWWP2A,BEND6,MTA3,GPR158,HACE1,OSBPL8,AK2,BCAR3,PCDH10,UNC79,AMPH,LRCH2,LCORL,PPFIA2,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APBB2,MAGEE2,DDO,AQP4,PPP4R4,CASK,RGS20,CDK13,DACT3,ZBTB10,NCOA1,ASTN1,SLC4A4,ATP1B3,DOCK11,BACH1,SNAI3-AS1,RGS9,FUBP1,BSN,CDK5R2,BTRC,SLC16A4,TMEM257,CDC42,LGI1,L3MBTL4,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,NGEF,LY86,AKAP7,PCYT1B,ARMC8,BTF3L4,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,CHD1L,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ECE2,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,BRINP1,GIT2,SIRPA,DCC,HP1BP3,KIAA0753,DDX46,SNAP91,NTM,WDR20,NR1D2,ABI1,MAMLD1,EDIL3,EFNB3,FAM13A,PHF20L1,ABI2,EIF4G2,SORBS3,TENM1,EML1,STARD3NL,EIF1,EMX2,EPB41L2,EPS8,ERBB4,MRPL37,DNAJC27,CLVS1,ZIC4,SCML2,DLC1,RACK1,ST3GAL6,FKTN,TESK2,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXG1,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,STAG2,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,MTHFD2,LRRC37A6P,KIAA1841,GATM,DBF4,GLS,ZNF638,PRRC2B,GPM6B,FUT10,EML4,GRIA4,GRIK2,GRM8,GSTT2,LINC01551,SOX21,GUCY1B1,ZHX1,HMGB1,HMGCR,LRRC75A,HTR5A,EID2B,C5orf24,IGFBP1,INSM1,ZNF385B,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNMA1,KIF5C,IPO5,INSYN2,PAXBP1,HECTD2,FGFBP3,NCOA7,PACRG,C1orf194,MAP4,MARK3,TM6SF1,MEIS1,AFF1,MMP16,MYH3,BEX5,NAP1L2,NEK1,NELL2,NEUROD1,NFIA,NFIX,NKX2-2,NODAL,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PIRT,PDGFRA,PDYN,PFKFB4,CDK14,PIK3C2A,XRN1,FAM216A,PLP1,PCDH18,PMP22,SPATA6,EPB41L4B,PPARA,PPM1B,CRLS1,PPP2R5C,PPP2R5E,PPP3CB,NKAIN4,RANBP3L,PRKAB2,PRKACB,PRKCG,PKN2,EPDR1,DCHS2,LAMA1,MDGA2,CNTLN,ANKHD1,OCIAD1,PTPRG,STRC,MARCH1,SLC25A48,USP47,SH3TC2,C1orf54,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,SLC6A15,RET,GTDC1,RLBP1,SLC25A36,ZFHX4,RERGL,EXD2,C12orf49,ACER3,STK32B,LRRK2,LGR4,RPS20,SYNDIG1,RYR3,ZNF331,CCDC112,MIR124-2HG,SEMA6D,CSRNP3,ATXN7,LINC00461,RASA3,NLGN4Y,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,FBXO11,SYBU,ZNF365,FAM81A,SLC6A1,SEPHS1,ATF7IP,SMARCC2,SORCS3,LMBRD1,SNRPN,MYT1L,SOX11,DOK5,CLUAP1,ENKUR,HECW1,TSPYL2,MCF2L2,RBM26,SRPK2,TAB2,EPB41L3,ZC4H2,SS18,ERBIN,ZSCAN29,SEPT8,DIP2A,STXBP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,DDHD2,KLHL4,TBX15,ATMIN,DMXL2,ZEB1,NAT16,RALYL,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TMOD1,CSMD1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,CADM1,PITPNB,PLEKHH2,XRCC4,ZNF28,ELFN1,SPHK2,REEP1,MEIS3,PMEPA1,ZXDA,PRDM2,TMEM178A,C12orf4,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,SENP7" MicroRNA hsa-miR-1303:mirSVR_highEffct hsa-miR-1303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-137 1.00E-133 2.74E-136 2.53E-135 336 1338 "ACTN2,CCDC85A,GALNT13,SORCS1,KIAA1211,ADORA3,DPY19L2P4,SLC24A4,WDR35,CEP126,ARHGAP20,FAM135A,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,ALS2,FAM131A,API5,SHTN1,MIER1,KIAA1614,DACT3,TMEM108,ATM,RNF182,BACH1,RGS11,DCAF5,ZNF599,CACNA1G,DDR1,CALB1,THSD7A,PTBP2,CH25H,CBLN1,CBS,MTMR7,INA,LRBA,ZBED1,CDH10,LRRFIP1,L3MBTL4,MAGI1,COPB2,CHN1,PPT2,MAP4K4,LY86,CNTN1,BTF3L4,TBPL1,CREM,ENTPD4,RNF14,SLC32A1,CLIP3,TRIM69,MICAL2,CSNK1E,CSNK1G3,ATRNL1,CALY,ERC2,CTNND1,PUM1,RIMS2,CENPL,DAPK1,GIT2,ARMCX4,YTHDC1,ZNF804A,MYEF2,ELMO1,MAGI2,SV2B,TMCC2,DLG2,DMTF1,CASP8AP2,DPYSL2,ACOT8,DNM1L,GOLT1B,E2F6,EBF1,EDNRB,ANKRD46,FCF1,RASGRP1,FSD1L,PHF20L1,EBI3,EGR3,CALCRL,DCTN4,EPB41L2,SEZ6,KCNMB2,RCSD1,SH3YL1,ZIC4,ATP8A1,ZSCAN30,GORAB,GTF2IRD2,FGF1,FGF11,HPCAL4,FOXG1,CAP2,FOXO3,SEMA4D,TACC2,STAMBP,ATP2C1,DLL3,AP4B1,ZMAT1,STAG2,GABRA2,GAD2,ERAP1,DISC1,DNER,GATM,TUBGCP4,GDF9,ADAM28,GFRA2,PPARGC1A,LYVE1,ZNF276,CRCP,TCERG1,DBF4,ZNF638,GNAL,ZNF782,GPD2,FUT10,CCDC184,FAM19A2,RNF165,LINC01551,RNFT2,ZHX1,FRMD3,TNFAIP8L3,MIER3,SHISA6,HTR2A,MSL1,ZNF546,IGSF1,SCIN,ITGAV,SLC35G1,KCND2,KCNJ16,KCNMA1,INSYN2,MAP2,MATN3,MBD1,MBNL1,SYT9,SRSF12,XRRA1,ADAM22,CTNNA3,MTTP,MYO6,MYO9A,NCAM1,NDP,NDUFA5,SLCO1C1,NOVA1,HCN1,P2RX7,P2RY1,DPY19L2P2,PCDH9,PDE1C,PDE2A,PDGFRA,ENPP2,FAM218A,GPSM2,FAM216A,ST8SIA5,HMGCLL1,POLR2F,POU3F2,TATDN3,PPP2R5E,PPP3CA,PPP3CB,PRKACB,EPDR1,HYDIN,WBP1L,SYTL2,SIDT1,SNRK,CNTLN,PTCH1,MTMR10,PTPRG,CEP97,RAP1GDS1,VEPH1,KHDRBS2,MSANTD2,RDX,RGS12,SEC61A2,RIC8B,ZFHX4,ZNF532,ARMC5,ROBO1,RPE,MCMBP,GLDN,PTGR2,TRAPPC13,AP1AR,SAFB,SALL1,CSRNP3,ATXN2,LRRTM4,SCN8A,GALNT10,STUM,PPM1E,ASAP3,NTNG1,SHC4,MAGI3,SYBU,FAM81A,SLC6A11,SLC8A3,CCDC88A,SLC15A2,MTERF2,SPHKAP,TET1,EPC1,RCOR3,MAPKBP1,MBD5,LMBRD1,SON,WDTC1,SOX1,MYT1L,BDP1,NMNAT2,CLUAP1,HECW1,SRPK2,TAB2,TROVE2,ITPRID2,SAMSN1,SS18,DIP2A,KLHL7,ZC3H4,PRRC2C,SYNE2,COBL,TACR1,DDHD2,CAMSAP2,FAM208A,UNC5D,KIAA1107,KLHL4,ANO4,VWC2,DMXL2,TCF7,ZEB1,TCF12,WASHC4,WDR7,TMEM151B,SLC19A3,PCDHAC2,ARHGAP9,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,ATP13A2,FAM200B,C18orf54,LEFTY2,TJP1,TMPO,R3HDM1,RBFOX2,RASD2,NPL,TRIO,FAM155A,UGT8,ZIC1,ELFN1,ZNF45,AGMO,GPR158-AS1,ZSCAN26,ANKS1B,SMARCAD1,MEIS3,CADM2,PRDM2,STMN4,PRDM10,FAM13C,PHTF2,TIGD6,NETO2,SENP7" MicroRNA hsa-miR-124-3p.1:TargetScan hsa-miR-124-3p.1 TargetScan 2.02E-137 1.13E-133 3.10E-136 2.85E-135 330 1291 "ABR,ACHE,FMNL2,GALNT13,PLEKHH1,ESYT2,NLGN4X,CASKIN1,PCDH19,OSBPL6,OSBPL8,AK2,LRRC7,ALCAM,AMPD3,LRFN1,PHF12,ANXA7,APBB2,GPAM,ALS2,CPNE5,PDXK,ARHGDIA,ARRB1,CADPS,CDK13,ASPA,CHRD,DDX3Y,ATP1A1,NOL4,DPY19L3,RGS9,BCL7A,DCAF5,NRP2,BID,BMPR1B,DST,FUBP1,JAZF1,NIPA1,MYRF,LDLRAD4,MMD2,CACNA1E,CACNA2D1,CACNB2,CACNB4,PTBP2,MAP7,ARHGEF1,CDH2,JAM2,LHX2,QKI,NIPBL,CNN3,CNTN1,AKAP6,MYRIP,NRG2,FAM171B,CLOCK,ANKRD44,CLIP3,LRIG1,OSBPL3,IPCEF1,GALNT9,PLCXD3,ARHGEF4,CTNND1,PPP6R2,MYADM,ARHGAP32,GAPVD1,HDAC4,PHF19,KIF26A,LONRF1,MAML1,IST1,DAPK1,AIF1L,GIT2,ELMSAN1,BLOC1S6,GUCD1,G3BP2,MTX3,GRIN3A,DMD,DNM2,RCAN1,DTNA,DYRK1A,E2F5,E2F6,EBF1,FAM135B,EDNRB,HIPK3,FSD1L,RBM12,EFNB3,CELSR3,PAN3,DCTN4,EN2,RAB9B,EPS8,CEP85L,ETV1,EXTL2,EYA1,REEP2,MED12L,FGF14,PRKAG2,PCYOX1,ANKFY1,C2orf88,NPTN,GPR153,MPP6,GABRB1,GABRB3,ILDR2,IQGAP2,ARFIP1,PCDH17,NTNG2,GLRB,KIAA1958,KCNMB4,GNAL,GPT2,GPD2,GPM6B,FUT10,GPR26,GPR37,RAPGEF1,GRIA2,GRID1,RFFL,CACFD1,NR3C1,GSN,KIF3A,RNF165,KAT7,RASSF8,PADI2,ARHGAP19,BACH2,HLF,ELOVL5,HP,NEGR1,ATCAY,PLD5,LIX1,INSM1,ITGA7,ITPKB,KCNA1,OLFM3,KCNA6,KCNB1,CLVS2,KCNK2,KCNK3,KCNN3,KCNQ3,KIF2A,LIMS1,HECTD2,NAT8L,MARK1,MAT2A,MATN2,CHIC1,MID1,PPM1L,POC1B,MITF,AFF1,JAKMIP3,ADAM22,MSRA,MTR,MYO5A,MYO9A,NAP1L1,NAP1L3,NCAM2,NEUROD1,NFIA,ALDH1L2,NFIX,NHLH1,NME4,NRCAM,NUMA1,P2RX7,KCNK10,PALM,CNTN3,PCDH8,CDK18,PDE2A,PDE4A,PDE4B,PDE4D,GPR173,GPR85,GNG2,GDAP1L1,PIK3C2A,PLEC,PRRX1,PPP2R5E,PKN2,MAPK4,MAPK10,PROX1,MDGA2,MTMR10,PTPRD,EML5,PTPRZ1,QDPR,RAD17,RALGDS,ENOX1,DUSP15,MORC4,FIGN,RFX3,RFX4,SEC61A2,DCUN1D2,ALG9,RAVER2,EPHA10,CLIP1,RXRA,RYR1,RYR3,DRAXIN,SCN2B,SCN4B,CASC3,GALNT10,COPZ1,KIF16B,DZIP1,FAM81A,EPN2,RUFY2,ARHGEF40,CCDC88A,ELMO2,BTBD7,ATF7IP,EPC1,LIMCH1,PALLD,PDZD2,KIF21B,CAND2,RAP1GAP2,NFASC,LMO3,C11orf87,CAMTA2,NKAIN2,NXT2,PHLDB1,KANK1,RHBDL3,PLCB1,ATP11A,ATMIN,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ARL10,GZF1,NACC2,DAAM2,RIMBP2,RASD2,NR2C2,ANO5,CADM1,AMOT,GORASP1,FRRS1L,OSBP2,BCL2L13,CLDND1,REEP1,FSTL5,EML6,DPYSL5,ANKS1B,PMEPA1,PRDM2,CSDE1,EVI5,GDPD5,LMAN2L,ADAMTS9,NAV3,NAV2,ITM2C,MARCH8,FBXO36,FAM219B,FXR1" MicroRNA hsa-miR-146b-5p:mirSVR_lowEffct hsa-miR-146b-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.23E-137 1.25E-133 3.41E-136 3.14E-135 397 1855 "ACADM,EMILIN3,CSMD2,ARID1A,XKR4,FMNL2,ADCY2,CCDC85A,ADD1,RNF150,MTA3,AP2A2,ZNF608,GPR158,SNX32,CASKIN1,OSBPL1A,OSBPL8,ZNF578,ABCD2,GPRASP2,SYT13,AMPD3,ANK2,CCDC146,ANXA7,ALS2,USP37,SHTN1,PPP4R4,TMEM263,DNAH17,ASPH,ATM,ADAM23,ADAM15,LINC00847,BCHE,RGS9,BLM,DST,SYNJ1,OSGIN2,MMD2,CACNB4,CALB1,SLC25A14,PRC1,CD86,TMEM257,REPS2,CDH8,DCLK1,CDH18,DLGAP1,UBE2L6,GPR37L1,CHRNB2,CLTA,CNTN1,AKAP7,FAM149A,AKAP5,RCHY1,ZFP28,CHD1L,SEC31B,CREM,RBM39,RNF14,ANKRD44,CRYM,CS,OSBPL3,ATRNL1,GALNT9,PNPLA8,GREB1,ARHGEF4,CFAP61,ZSCAN23,ECE2,ARHGAP32,GAPVD1,SNPH,RASSF2,IST1,DNAL1,HEPH,CNIH3,FBXL5,KIAA0319,LYPD1,SGSM2,DLG2,DLX1,GRIN3A,DOCK2,DSCAM,FAM135B,HEYL,EBI3,MBNL2,EGR3,TMEM132E,AASS,TENM1,CALCRL,SEZ6,EPHA5,RABEPK,EPS8,NCALD,EFS,CDHR1,MRPL10,DUSP27,RCSD1,TLR7,KATNAL1,ADGRV1,MRVI1,FAM198B,DLC1,ST3GAL6,CHST15,ZNF589,FECH,FER,GTF2IRD2,OLFM1,CAMSAP1,PCYOX1,SYNCRIP,IQCG,FLT1,SORBS1,SMC2,ATP6V1H,ATP2C1,ZNF605,STAU2,PNMA2,NRG3,ZNF512,GABRA1,GABRG1,GAD1,GAD2,GALR1,IP6K3,ERAP1,SIGLEC8,ZNF559,ACSS1,GART,WASF3,KIAA1841,SULT1C4,SESN1,GGTA1P,GLS,TOX3,MSL3,DCLK2,FERMT2,LILRB4,GPM6A,GPM6B,B4GALNT4,GPR19,GRIA1,GRIK1,SPACA9,PRDM5,GRM7,KIF3A,BVES,RABL2A,ADAMTS6,MUM1,PADI2,ZHX1,VSIG4,AGBL5,OPALIN,CELF5,HTR5A,MSL1,LINC00667,RAB41,GAREM2,SCIN,IL6R,ZNF678,KCNA6,CREG2,LAMA2,SYTL4,FGFBP3,NCOA7,C2orf80,ZFYVE27,MAP4,MAP6,LYPLAL1,MAT2A,CHIC1,TM6SF1,MEIS1,PPM1L,AFDN,BCO1,CTNNA3,MXI1,LAYN,MYO5A,MYO7A,ZNF862,NAP1L1,SFR1,NF1,NHLH1,NODAL,NPR2,HCN1,NTRK2,NTRK3,OPA1,PAK3,PCDH9,PCSK2,SERPINE2,ANLN,XRN1,KCTD15,NLE1,PLCL1,PLP1,TRHDE,PRRX1,MAGEL2,SLC36A4,TNPO2,NXPH1,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,PRKACB,MAPK4,GRAMD1C,SIDT1,PIGG,CNTLN,PTAFR,PTCH1,UHRF1BP1,ZSCAN32,PTPRZ1,TMEM255A,RALGDS,SH3TC2,NWD1,RASGRF2,RFX2,SEC61A2,RNASEL,C12orf49,ELP2,NEK11,ZC3H14,GLDN,ACER3,SALL1,SATB1,LRFN5,LRRTM4,PRCD,SCP2,GALNT10,FOXRED1,MRAS,TRA2B,COPZ1,MAGI3,CHD9,FHOD3,CTXN2,CLSTN1,ZNF365,PPP4R3A,DHX30,RUFY2,SLC6A1,SLC6A7,ARHGEF40,SLC9A5,SLC11A1,ZFP1,RCOR3,IGSF9B,INAVA,LIMCH1,MBD5,SNRPN,TMCC1,UNC80,SCN3B,DOP1A,TRERF1,SOX10,FNBP1,DOK5,ZSWIM8,NPAS3,SPART,ATP10B,ITPRID2,SMOC1,NECAB1,SYT11,ZC3H4,SYN2,SLC37A2,TACR1,DNMBP,PDLIM2,UNC5D,TMEM136,MGRN1,ATMIN,SIN3B,WDR7,ARHGEF12,USP32P1,FRYL,CCDC173,SIK3,VWCE,PMS2CL,DICER1,SIRT1,ZFPM2,ITGB3BP,GALNT17,TIAM1,MTMR14,TIMP4,BHLHB9,TLR4,DAAM2,PRRT1,CSMD1,C5orf64,SEZ6L,TPD52,ZNF346,SYNPO2,FNDC5,ANO5,TTTY15,CLHC1,CADM1,MTCH1,MEAF6,WIPF1,WRN,XPO1,SF1,ZIC3,ZFAND5,SMARCAD1,SYNC,EMSY,PRDM2,DNALI1,LRP8,SLC38A1,LINC02210,ADAMTS9,HPS4,NAV2,FAM47E,PCBP4,MPPE1,WNK3,MVB12B,C12orf4,FZD3,UBE3B,KAT6A,ZNF248,FRMD6,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-567:mirSVR_highEffct hsa-miR-567:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-137 1.32E-133 3.58E-136 3.30E-135 304 1093 "KCNH8,ACLY,ABHD6,ARID1A,CSMD3,GALNT13,KIAA1211,KIAA1324,C1QTNF3,LRRC7,ALCAM,ABCD2,ARHGAP20,OGT,MAP4K3,APAF1,GPAM,TNRC6C,MIER1,PPP4R4,ATP1A2,EIF4G3,DST,MTMR2,JAZF1,WASF1,CALB1,KALRN,CAMK2D,CBLN1,KRIT1,LRBA,CDC27,CDC42,KCNAB3,TIGD7,CHN2,CASC2,TAOK2,CLTA,C4orf33,CNTN1,AKAP7,ARMC8,BTF3L4,AKAP5,SLC4A8,AKAP12,ABCG1,CSF1R,OSBPL3,ATRNL1,APPL1,UBXN2A,PHF14,CTNND2,PUM1,ECE2,GAPVD1,ARHGAP24,EARS2,KIAA0586,TMEM170A,TOMM20,DCC,PITPNC1,MYEF2,CNIH3,MAGI2,GSDME,SNAP91,ZNF582-AS1,DLG2,NR1D2,PDCD6IP,ABCC5,GOLT1B,EBF1,EDNRB,ANKRD46,TMTC1,MBNL2,EGR3,EIF4G2,PLEKHA1,CALCRL,VPS13B,EPB41L2,NCALD,CEP85L,MRPL37,VPS26C,NRN1,TMEM132C,DLC1,FCGR3A,KIAA1109,FGF1,POLK,SUCO,CAP2,FLT1,PSD2,JKAMP,SORBS1,UFM1,ZNF605,CELF1,ST6GALNAC3,STAU2,GAB1,GABRA2,ZMYND11,NCKAP1,DISC1,LRRC37A6P,DNER,GATM,MSTN,PCDH17,LYVE1,GK,COPS8,CBX1,GPM6B,ATF7,GPR34,RAPGEF4,ATP2B1-AS1,GRIA4,GRIK2,GRM1,GRM7,GYG1,HAS2,SMAP1,MSL1,RBPJ,DOCK7,PLD5,USP54,LIX1,INSM1,KCNJ16,KCNK2,CREG2,KIF2A,STXBP5,INSYN2,ARHGAP12,NCOA7,SMAD1,PIK3AP1,MARK1,LYPLAL1,AQP11,MBNL1,MDM4,AFDN,XRRA1,MOBP,ZNF92,NCAM2,NDUFA5,NEUROD1,NEUROD2,NF1,DNHD1,SLC11A2,NRCAM,HCN1,NTRK3,TBC1D25,OLR1,OPA1,CLDN11,PBX1,ETFRF1,PRTG,PDE3B,PDGFRA,ENPP2,PENK,BEST3,FAM98B,OLA1,DUSP26,A2ML1,SNX10,TRHDE,STRN3,LRP12,PSAT1,SPATA6,TMEM235,PPP2R5E,NKAIN4,GRAMD1C,GDPD1,SAMD9,VPS13C,MDGA2,QRICH1,PTAFR,PTCH1,ANKHD1,TMEM260,RAB3A,CCDC40,PLEKHB2,FAT4,OXR1,DBX2,RFX3,TTLL7,NUDT11,RNASEL,TMLHE,EXD2,ROBO1,CCDC102B,RPL15,ATP8B4,TCP11L1,CNTNAP3,RTKN,CLIP1,ZNF354C,CCDC112,TRAPPC13,FAM19A1,SCN8A,LINC00461,FNIP1,HSPA4L,FHOD3,CTXN2,SEC31A,RUFY2,RAB3GAP1,CCDC88A,BTBD7,SPHKAP,SMARCE1,RCOR3,PALLD,USP33,TNIK,SOX15,ZC3H13,CDK19,CAMTA2,LARP4,NXT2,SEPT8,KLHL7,PRRC2C,VPS13A,ATP11A,MTCL1,DDHD2,AGTPBP1,SMG6,TCEA1,TCF4,SYNE1,OBSL1,RNF175,SIK3,CRB1,ITGB3BP,AP4E1,SLC44A1,ARL10,ERCC6L2,TMPO,C5orf64,TPM1,C9orf85,TMEFF2,BEST1,RICTOR,GUSBP1,XPO1,CFAP298,ZNF708,ZNF19,ZNF28,ZNF138,ANKS1B,SYNC,ZNF225,CA10,CADM2,PRDM10,RNF103,KCNAB1,FIP1L1,C12orf4,PHTF2,ADAMTSL3,JMJD1C,FXR1,CBLN2" MicroRNA hsa-miR-532-5p:mirSVR_lowEffct hsa-miR-532-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.50E-137 1.40E-133 3.80E-136 3.50E-135 380 1706 "CLK4,AS3MT,NDRG3,SLITRK1,TMCC3,NLGN4X,ZNF608,RTL9,HACE1,ALAD,ARHGAP20,SYT13,AMPD3,ANK2,PARG,APBB2,PHYHD1,SHTN1,SHROOM2,AQP4,MIER1,PDXK,IGDCC4,ARHGAP5,CDK13,STK33,ASPH,ZSCAN18,DACT3,ATP2B1,SLC2A11,MTMR9,B3GALT2,N4BP2L1,NOL4,RIPK1,TTLL9,BBS2,BCHE,RGS9,NRP2,MTMR3,SGCE,IL33,BTRC,CACNA1A,THSD7A,PTBP2,SLC25A14,MAP7,NFS1,PRC1,ZNF501,CLDN10,RGN,SLC16A4,LRRFIP1,MAGI1,CACNA2D2,DIS3L,SRSF11,RAB28,FAM19A5,SRP14-AS1,MAP4K4,NIPBL,CNGA3,CNN3,IQCK,PCYT1B,AKAP5,SLC4A7,SLC4A8,ABI3BP,MYRIP,CNRIP1,FAM171B,SEC31B,C2CD2,HINFP,ANKRD44,CS,RGS6,LRIG1,CSNK1E,SIPA1L1,PDE4DIP,CST3,PLXNA4,FAM169A,DZIP3,APPL1,PHF14,CTH,GREB1,ST18,CCDC144A,KIAA0408,DOCK4,RIPOR2,TOX,ZFYVE16,EARS2,ZNF337,TMEM170A,DAPK1,AIF1L,ARMCX4,PITPNC1,DNAJC6,ZEB2,HEPH,TIAM2,MFAP3L,COPS7A,KLHL3,EXOG,MED12,NR1D2,DNM2,DRP2,RCAN1,DTNA,DYRK1A,SNX29,WDPCP,EDN3,TMTC1,FRY,SUGP2,MBNL2,SORBS3,IRAK4,ELAVL2,GPHN,SRRM1,TMEM74,MRPL10,ETV1,SIRPB1,GMPR2,CLVS1,TBC1D16,ATP8A1,CEP78,FECH,MED12L,GTF2IRD2,FGFR1,TMEM164,AMOTL2,SCARA3,UBE2E3,FOXF2,PCYOX1,SYNCRIP,NOP56,TMEM107,UFM1,NPTN,NSG2,TBR1,NRG3,MEGF11,GAB1,ARPP21,SYT17,C15orf41,ACSS1,LRRC37A6P,MYOZ2,GATM,GFER,MALT1,GLS,TOX3,TNRC6A,MSL3,CBX1,LUZP2,GPR22,CECR2,PCLO,GRIA4,GRID1,GRM7,CIT,LINC00839,AP4S1,PSIP1,MAEL,DDX19B,AGBL5,USP51,LRRC75A,FAM95B1,LINC00667,C2orf72,INPP5B,ITGAM,KCNC2,KCND2,KCNJ3,KCNJ9,KCNK2,KCNMA1,A1BG-AS1,TTYH2,STMN1,SFXN5,SYTL4,MARK1,MBD1,MBP,CHST6,TM6SF1,MMP16,MOG,CCDC80,SCG3,DDX25,NELL2,NEUROD2,NINJ2,DNHD1,NTRK2,NUCB2,NUMA1,CHAMP1,OPHN1,LOC100128398,CLDN11,KCNK10,PDE1C,PDE2A,PDE4D,PDGFRA,GPR173,GPR85,BEST3,LRP12,PRRX1,POLG,TATDN3,PPP2R5C,PPP3CA,RAB39A,PRKCG,MASP1,CNNM2,WBP1L,PIGG,PLPPR1,UHRF1BP1,ELOVL2,PTN,PTPRH,ZSCAN2,ZNF615,RAB3IL1,TMEM255A,PLEKHB2,ZNF793,RALGDS,RDX,ZYG11B,DPF2,RGS4,RGS12,ARHGEF10L,TTLL7,RIC8B,C12orf49,PCMTD2,NEK11,ARMH4,GLDN,SGSM1,ACER3,RTN1,CSRNP3,ATXN7,SCP2,SEC14L1,SOX6,KIF27,ITSN1,PPM1E,FHOD3,CTXN2,ABLIM3,SLC6A7,SEPHS1,SLC12A2,RIMS1,MBD5,CMTR2,SNRPN,TMCC1,FAM126B,UNC80,WDTC1,BDP1,IDI2-AS1,KIF1B,COLGALT2,STOX1,ZC4H2,CEP68,ADHFE1,C3orf70,TMEM150C,SYN2,ANKRD28,SYT4,POPDC3,KAZN,MTCL1,PJA1,DDHD2,UNC5D,CNTN2,KLHL4,TCF7L2,TPCN2,TRIM2,SZT2,SYNE1,SLC19A3,AKNA,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,ZFPM2,C18orf54,AP4E1,HHIP,ARL10,ANKRD24,KCTD2,TNFRSF1B,TPD52,TPM3,C9orf85,TRIO,AMACR,TRO,FNDC5,LRTM2,GORASP1,UGT8,SLAIN1,FLRT2,FLRT1,ZNF709,XRCC4,CELF4,ANKS1B,WNK1,DNALI1,STMN4,STOX2,SCG2,VPS35L,TRIM16L,MVB12B,HNRNPA3,PHTF2,FBXO36,ACTR3B,TIGD6,SSPN,NETO1,CPNE4,SENP7" MicroRNA hsa-miR-134:mirSVR_lowEffct hsa-miR-134:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-137 1.72E-133 4.66E-136 4.29E-135 366 1587 "ASIC2,ASIC1,KLHL32,RNF157,ADD1,ADORA2A,KIAA1211,OLMALINC,ZNF608,INTS2,TXNDC16,ZNF578,ALCAM,PCDH10,BBOX1,AMPD2,DPP10,MAP4K3,MYH7B,CNIH2,KCNAB2,GPAM,BCAS1,TNRC6C,SHROOM2,CASK,ARRB1,LINC00173,SLC4A4,STX16,TTLL9,ADAM15,SEC11C,RGS11,ARHGEF7,LINC00906,BTK,SCAPER,JAZF1,NIPA1,CFAP410,CACNB4,CALM1,SPAG9,INA,TMEM257,ENTPD6,C1orf52,SEPT7,CDH8,LRRFIP1,DLGAP1,UBE2L6,FOXN3,B4GALT6,KIAA1549L,CLTA,ABCG2,SRP14-AS1,CNR1,AKAP6,COL4A5,SLC4A8,IFFO1,COX4I1,SMARCAL1,ZNF385A,ABCG1,CSF1R,CSF3R,CSNK1E,CSNK1G3,VCAN,SOCS5,FAM169A,SDC3,ARHGEF4,RIMS2,GPSM1,RUBCN,KIAA0408,DOCK4,ARHGAP32,FRMPD4,INTS1,PHYHIP,SCRN1,DNAJC6,ZEB2,TIAM2,MFAP3L,KIAA0753,MAGI2,CHRDL1,DLG2,DLX1,GRIN3A,DMD,DNM1,HS3ST2,SLC29A4,CDON,CPEB2,DTNA,DYRK1A,ABCC5,KRBA2,EDN3,ANKRD46,RASGRP1,PHF20L1,KMT5B,EGR3,PLEKHA1,ELAVL3,PAN3,ZNF549,MRPL10,TOMM40L,TESK2,ZNF589,FGF1,FOXM1,FLT1,SLC37A3,NELFCD,NBEA,TMEM107,HVCN1,UFM1,CAMKK2,CELF1,STAU2,KBTBD12,AP4B1,OGA,ZMAT1,DKK3,GABRB1,ZNF559,SRRM4,GATM,GCNT2,NFU1,PPARGC1A,TTBK1,CRCP,RNPS1,HPGDS,GLUL,ZNF782,ADGRA3,GPD2,GPER1,NUDT21,ATP2B1-AS1,RAPGEF1,GRIA1,GRIA2,GRM1,FAM19A2,KAT7,IRAK3,RASSF8,GPR45,ARHGAP36,ACOT7,HPSE2,GABARAPL2,HMGCL,NEGR1,OPALIN,IDH3A,TJAP1,PLD5,HES5,IL6ST,BRINP3,KCNA4,KCNA6,KCNC2,KLHL23,KCNJ16,CREG2,STXBP5,LIMS1,PAXBP1,ARHGAP12,NCOA7,CHIC1,LDLRAD3,MEIS2,MGAT3,PPM1L,MKLN1,RSPO2,MYCN,MYO5A,PABPC1L2A,NCAM1,NDUFA5,NEUROD1,NF1,NUCB2,NUMA1,TBC1D25,OCRL,GPR88,OPCML,GPR137C,KCNK10,PAK3,DPY19L2P2,PCDH9,PCSK1,PCSK2,PDE4B,PDE4D,PDPK1,CAMKV,ANLN,PLCL1,FTO,SLC25A23,PRIMPOL,TNPO2,RANBP3L,BCAS3,SYTL2,MTMR10,TMEM260,NKAIN1,QDPR,MARCH1,PID1,CEP97,SLC25A48,CCDC40,FAM66C,RALGDS,ENOX1,OXR1,RASGRF1,VEPH1,RDX,ZMAT4,REV3L,GTDC1,RFX5,RGS4,RGS7,ARHGEF10L,EXD2,ALG9,KIRREL1,SNX22,EPHA10,FBXW7,SPIN3,ZC3H14,ZNF671,MCMBP,GLDN,ACER3,MAP6D1,RXRG,NCBP3,ZNF331,AMER2,HOGA1,LRRTM4,FNIP1,ELMOD1,PPM1E,CPEB3,WDR37,CCDC88A,SLC12A4,SLIT1,CPEB4,MAST1,MYH15,FAIM2,PALLD,DOP1A,PDZD2,DOK5,ENKUR,UHRF1BP1L,KDM4C,UNC5B,SPART,LHPP,TAB2,ATP10B,TROVE2,STOX1,NKAIN2,ZSCAN29,FAM168A,SYT11,C3orf70,SYN2,COBL,MTCL1,PJA1,ADGRL3,VWA3A,SIN3B,RPGRIP1L,CLASP1,SZT2,WDR7,SYNE1,PHF24,PCDHB7,PUM2,TNS2,FRYL,CCDC173,PMS2CL,AP4E1,TGFBR3,ZNF106,MTMR14,TMOD1,DAAM2,FAM124A,TNFRSF1B,PIK3R5,SEZ6L,ELP5,TRIO,TRO,STXBP4,DCBLD1,TMPRSS5,ANO5,PLEKHH2,CCDC136,LAT2,NSD2,KLC2,CLDND1,KCNK12,ZNF45,LYPD6,TMEM237,POLR3H,EML6,SMARCAD1,SYNC,UPF3A,ZXDA,RNF103,FIP1L1,EPM2A,DOCK8,ST7,HNRNPA3,NUP214,FAM219B,RNF170,SNX14,FAM181A,SENP7" MicroRNA hsa-miR-361-5p:mirSVR_lowEffct hsa-miR-361-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.84E-137 2.72E-133 7.33E-136 6.75E-135 375 1666 "VWA5B2,ACLY,ARID1A,CSMD3,NDRG3,ADCY2,PWWP2A,KIAA1211,PCDH19,OSBPL8,ALCAM,ABCD2,ARHGAP20,GOLGA7B,UNC79,OGT,CDC42BPA,LRCH2,EP400,PARG,APBB2,UPRT,PPP4R4,ARRB1,ASPH,NCOA1,ASTN1,DYNLL1,SLC4A4,MTMR9,BACH1,FUBP1,NAE1,WASF1,IL33,CACNA1E,CACNB4,CACNG1,CALB1,KALRN,HAP1,VXN,VSTM2A,CH25H,BRSK2,ISPD,LDB2,USP6,MTMR7,INA,AIFM1,CDC27,CDC42,ZMYM4,DLGAP1,CIART,CFL2,SOCS6,IGFBP7-AS1,KIAA1549L,CLU,TPP1,CLTA,FADS2,C4orf33,NIPBL,ARHGEF6,COL9A1,RCHY1,ACBD5,CNRIP1,SLC35F1,SLC32A1,ANKRD44,GDA,CSF2RA,CSF3R,VAC14-AS1,PLCXD3,PUM1,ZSCAN23,CX3CR1,CCDC144A,KIAA0408,TOX,ZFYVE16,LIN54,MATR3,KIAA0586,KCTD8,IST1,DAPK1,SCRN1,ARMCX4,JAKMIP2,ZBTB24,TIAM2,FBXL5,KIAA0319,PLPPR4,SV2A,KBTBD11,DLG2,EXOG,NR1D2,DYRK1A,DNM1L,E2F5,EDNRB,FSD1L,SH3GLB1,PHF20L1,COPS4,ELAVL2,ELAVL3,C3orf18,VPS13B,EPB41,LRRC17,EPHB1,KCNMB2,ERBB4,CEP85L,ZNF549,TMEM74,DUSP27,WAC,RPS6KC1,DLC1,FKTN,ZNF589,FGFR1,PCYOX1,SYNCRIP,FLT1,EFCAB2,JKAMP,SORBS1,HVCN1,PDLIM5,TPK1,KHDRBS3,CSPG5,NSG1,STAU2,ZNF512,PHYHIPL,STAG2,GABRA1,GABRB1,HBS1L,BRPF3,NCKAP1,ERAP1,SIGLEC8,DISC1,DNER,GCNT2,MSTN,PCDH17,GHR,HPGDS,MSL3,LILRB4,PRUNE2,FUT10,GPR22,DIDO1,GRID1,GRIK1,NR3C1,GRM1,GRM5,GRM8,FAM19A2,KAT7,GYG1,WIF1,MUM1,IRAK3,MAEL,RASSF8,C1orf94,ARHGAP36,MIER3,AGBL5,HNF4G,HNMT,ZDHHC15,TCEAL6,DHX35,HSF2,MSL1,NKD1,IGSF1,LRRTM1,METTL21A,KCNA1,KCNJ10,KCNN1,KIF5C,STXBP5,PAXBP1,NCOA7,MAPT,MBP,LRP1B,MEIS1,MID1,XRRA1,MMP16,MOBP,MSR1,NRBP2,MYCN,LYRM9,TCEAL5,BEX5,SLCO1C1,NFE2L2,ALDH1L2,NFIX,NHLH1,NOVA1,DNHD1,NPR2,NTRK2,OCRL,CHAMP1,OGG1,OMG,OPHN1,CLDN11,P2RX7,PAK3,PRTG,PDE3B,PDE4D,PDE1B,SLC10A4,NALCN,RETREG1,XRN1,KCTD15,HMGCLL1,PURG,PMP22,STRN3,LRP12,EXOSC10,EPB41L4B,NXPH1,DRAM2,PPP2R2B,PPP2R5E,PPP3CA,PPP3CC,PRKCZ,BCAS3,PTCH1,BDNF-AS,MTMR10,TMEM260,PTPRB,PTPRE,PTPRG,PTPRO,FAM120C,USP47,PLEKHB2,ZNF493,ARID4A,RBBP6,KHDRBS2,ZMAT4,RET,RNASEL,RPRD1A,CCDC82,SETD5,TMLHE,ALG9,RPE65,FBXW7,SPIN3,ADAL,STK32B,LRFN5,LRRTM4,FNIP1,TNFRSF19,SMPD3,SEC14L1,GALNT10,TRA2B,PPP1R9A,PPM1E,SHC4,AMBRA1,NLGN1,PKNOX2,SEPHS1,KBTBD4,SLC12A2,MYH15,SMARCE1,SNAP25,SNCA,ZNF415,SNRPN,DOP1A,SOX5,BDP1,SOX11,ZHX3,ENKUR,IDI2-AS1,PEG10,CDK19,ZBTB43,RBM26,C11orf87,LARP4,NXT2,FCHO1,AJAP1,ARHGEF9,PLCB1,SYT1,ANKRD12,PJA1,ROBO3,TAF9,ACSL6,TCF4,AZIN2,DOCK9,USP32P1,ARHGAP9,GPRIN3,TGFBR3,SLC44A1,TPD52,DOK6,SYNPO2,TRIO,RUNDC3B,RUSC1,TSC1,TTPA,EIF4ENIF1,UBE2H,PITPNB,FLRT2,MEAF6,WIPF1,NSD2,CLDND1,SLC13A3,ZIC1,LYPD6,REEP1,DPYSL5,DHX33,GDPD5,PRDM10,TUBA1A,SIGLEC10,NAV2,SNX27,FAM47E,DOCK8,PHTF2,ZNF248,NETO1" MicroRNA hsa-miR-221*:mirSVR_lowEffct hsa-miR-221*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.23E-137 4.06E-133 1.09E-135 1.01E-134 399 1879 "TTYH1,DGCR6,CSMD3,NDRG3,ADCY2,ADCY5,GRAMD1B,ADORA2A,ADRA1B,OSBPL8,AK2,AMT,CDC42BPA,SEMA7A,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,APC,EPB41L5,AMER3,PDXK,TMEM263,PCDHGB4,ASTN1,SLC4A4,EIF4G3,DPY19L3,ADAM15,SNAI3-AS1,BCHE,RGS9,NRP2,OSGIN2,CDK5R2,BTRC,CA4,CA8,LURAP1,CALM1,SLC25A14,CAST,USP6,ARHGEF1,SCARB1,SYNGR3,LRBA,CHI3L2,CASC2,TAOK2,TPP1,FAM189A2,CABP1,SUMF2,BTF3L4,LETMD1,SLC4A8,ACBD5,MYRIP,MFSD4A,SEC31B,ANKRD44,NCOR1,TRIM69,CSF1,SUSD5,PLCH2,CST3,DZIP3,PPP1R16B,CFAP61,CTNND1,MYADM,HDAC4,PHF19,EARS2,ZNF337,TBC1D5,ACY3,TMEM170A,JAKMIP2,RUSC2,KIAA0319,ZC3H11A,GUCD1,SGSM2,WDR20,CCDC3,ZNF582-AS1,NYAP1,GNE,MAMLD1,DYRK1A,ABCC5,USH1C,EDNRA,PHC2,SYT15,CNNM1,RASGRP1,YAF2,EGFR,EIF5,IRAK4,ELAVL2,ELAVL3,TMEM35A,EPB41L2,RCAN2,STX2,ERBB2,SRARP,PIPOX,VPS26C,ANKMY1,ADGRV1,EZH1,RPS6KC1,TMEM132C,RACK1,STRADA,TESK2,KIAA1109,FGF1,POLK,SCARA3,HPCAL4,VTI1B,FOXM1,USP16,STAMBP,ZNF605,AP4B1,NEURL4,FAM184B,HBS1L,BRPF3,FAM120B,ZMYND11,B4GALNT1,ARPP21,GALR1,ZNF274,DISC1,SEPT9,GCNT2,CYP46A1,GGT7,GHR,CRCP,GNAS,GNG4,GPT2,WDFY3-AS2,GPD1,GPD2,PRUNE2,DIPK1C,LILRA1,LPAR4,GPER1,CECR2,RAPGEF4,GRIA1,GRIK3,CACFD1,GRIN2C,ATE1,LINC01089,COQ10A,AP4S1,FAM107A,FRMD5,MIER3,HLF,ELOVL5,DHX35,LRRC75A,RBPJ,KNDC1,USP54,IGSF1,SCIN,IL6R,IBA57,LRRTM3,SLC35G1,KCNC2,KCND2,KCNJ4,KCNK1,KCNMA1,KCNN3,A1BG-AS1,KLC1,L1CAM,C2orf80,LOC100128239,MAN2A2,ZFYVE27,MARK1,MBD1,SYT9,MEIS2,XRRA1,WDR49,ERICH3,SAMD5,BLOC1S2,MT3,FXYD6,SLCO1C1,NINJ2,VWA2,SLC11A2,NUCB2,NUMA1,OPHN1,P2RX7,TREM2,DPY19L2P2,PCDHGC3,PCDH9,PDE4D,PDGFRA,GNG2,SEMA5B,A2ML1,CCSER2,TMEM38A,JAKMIP1,PNMA3,PMP2,PSAT1,PRRX1,TNPO2,PPM1B,TATDN3,PPP2R5E,PRKCZ,MAPK9,WBP1L,CYBC1,TMEM104,CNTLN,PTCH1,PLPPR1,PTHLH,FAM66C,RALGDS,SH3TC2,DPF2,PRRT2,RFX3,RGS12,RNH1,PNMA8A,GSTCD,SNX22,RPL15,BAALC,MCMBP,ADAL,STK32B,ATAT1,ZNF568,AP1AR,MAPK12,SCN7A,TNFRSF19,FOXRED1,SCAF8,HKDC1,SLITRK3,SYBU,NLGN1,ST3GAL3,CTXN2,SEC31A,ANKRD6,ZNF365,RPH3A,SLC1A7,SLC2A5,PPP4R3A,DHX30,RUFY2,SLC6A9,SLC8A1,ARHGEF40,SLC9A5,SLC12A2,ATF7IP,LGI3,SLN,SMARCD3,IFT122,RIMS1,FAM126B,PDZRN3,KDM4B,SON,TRERF1,ZSWIM8,NFASC,LARP4,NKAIN2,SSPO,SEPT8,TTBK2,ADHFE1,NSFL1C,PRRC2C,ZFR2,SYNE2,VPS13A,ADAMTS17,ANKRD28,SYT4,TACC1,KAZN,CAMTA1,PDLIM2,ADGRL3,SMG6,TCF7,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,RALYL,PUM2,CYB561A3,DICER1,CRB1,ITGB3BP,AP4E1,TGFBR3,GALNT17,HEY1,ACTR6,BHLHB9,ZFP91,ERCC6L2,TMOD1,SEZ6L,CHST5,RGMB,NR2C2,ZNF346,SYNPO2,TRIO,NEIL2,RUSC1,KCNE5,TSN,TUBB1,HEPACAM,FLRT2,VLDLR,WIPF1,NSD2,NPDC1,ZNF19,TRIM9,ATP6V0E2,PLPP4,LYPD6,CELF4,TMEM198,DPYSL5,LAMP5,EMSY,GDPD5,LINC02210,PRDM8,WIPF2,PDSS2,CAMK1G,FAM219B,JMJD1C,TRAM2-AS1,TIGD6,ADAMTS10,SSPN,DPF3,JPH3" MicroRNA hsa-miR-1975:mirSVR_lowEffct hsa-miR-1975:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-136 8.55E-133 2.29E-135 2.11E-134 347 1436 "ABAT,ABR,CLK4,NCKAP5,ADARB2,TMEM132B,ADCY6,SORCS1,AP1B1,SNX32,NR0B1,AMPD2,KIF6,OGT,CNIH2,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APAF1,APP,SHROOM2,SPTBN4,ARRB2,CHID1,ATP1A2,ATP1A3,SLC4A4,ZNF583,MTMR9,RIPK1,KSR1,CDK5R1,BTK,MTMR3,C1QC,PRMT9,LDLRAD4,CFAP410,KALRN,PTBP2,TRIM41,CAPN3,VSTM2A,CBS,LDB2,SLC5A11,CDC42,LGI1,MAGI1,MS4A7,ARHGAP22,SLC22A6,IGFBP7-AS1,PPT2,CLCN4,NRXN2,FADS2,MAP4K4,IGLON5,AKAP7,COL4A5,COL11A2,RCHY1,SLC35F1,FAM171B,RNF14,HINFP,CS,CSF1,ATRNL1,FAM169A,SLITRK5,PPP1R16B,SDC3,APPL1,CTNND2,DCAF4,ARHGAP32,LONRF1,TM9SF4,SCRN1,GIT2,SPATA2,DCTN1,MFAP3L,BLOC1S6,DDX46,SRGAP3,G3BP2,RABGAP1L,EXOG,GRIN3A,DNM1,HS3ST4,NYAP1,USP3,FAM57B,DPP6,DPYSL2,DRP2,TOM1,MAMLD1,ABCC5,AASDH,EDN1,SGK2,HIPK3,FCF1,TMTC1,SIDT2,SH3GLB1,CELSR3,EGR3,RASA4,EIF4G2,IRAK4,EML1,LRRC17,MTSS1L,DENND4A,NCALD,NRN1,CACNG2,TBC1D16,ZIC4,TUBB3,ZMYND10,ZNF589,FER,HPCAL4,SYNCRIP,FLT1,CAMKK2,ATP2C1,ERGIC3,CELF1,SDCBP2,STAG2,BRPF3,TMEM8B,DISC1,CPLX2,CYP46A1,USP19,GHR,TTBK1,RND1,CRCP,GLI2,RAB30,TNRC6A,INSM2,GPD1,STMN2,GRIA4,PLCD4,GRID1,ATE1,GRM2,CIT,BTN2A1,KIF3A,RNF165,GSTM5,RNFT2,TMEM179,CELF3,HAS2,NXPH2,MAN1B1,ARHGAP19,ATXN2L,ARHGAP36,ELOVL5,DHX35,LRRC75A,CELF5,MSL1,ZNF546,C5orf24,KCNK2,KHK,TTYH2,SFXN5,FGFBP3,MAOB,MAP2,MAPT,ADAM11,MEF2C,MIA2,SCAMP5,SAMD5,JAKMIP3,HS6ST3,NASP,NELL1,NEUROD1,NFIX,NNAT,NPTX2,SMIM11A,NTRK3,CLDN11,ZDHHC22,KCNK10,CNTN3,PDE2A,PDE4B,PDE1B,PFKFB4,OLA1,PIK3R1,TMEM38A,PLCD1,SMIM7,STRN3,SCHIP1,SEPT4,MBOAT7,TNPO2,POLR2F,FSD1,MINDY2,CRLS1,NKAIN4,PPP5C,PRKAB2,MASP1,CNNM2,APTX,MDGA2,TMEM104,ZIK1,PTPRN2,FAM120C,FAM66C,IQSEC3,RAP1GAP,NWD1,ENOX1,PRRT2,RGS4,KCTD17,MRPS18A,NUDT11,PBRM1,RPRD1A,SUGCT,KLHDC8A,PNMA8A,GSTCD,PAQR6,HUNK,ST6GALNAC6,WLS,CLIP1,RXRA,NCBP3,SCN2B,ASIC4,ZFP2,PEAR1,CASC3,GALNT10,ASRGL1,RASA3,NTNG1,CHD9,SLC1A3,SLC1A6,FAM81A,PEX26,PPP4R3A,LRRC55,SLC8A2,KBTBD4,SLC12A2,SLC12A4,SLCO1A2,EPC1,SMARCD3,SMARCE1,INAVA,UNC80,WDTC1,TRERF1,ZSWIM8,EMC1,SPTAN1,LMO3,PBLD,POGZ,ZC4H2,LRRC4,MAPK8IP3,GANAB,STXBP1,FGD4,JMJD6,NUDT10,ANKRD28,C12orf76,WWC1,TBCEL,FBXW11,TMEM136,TBX15,SIN3B,ZFP90,TCF12,CLASP1,SZT2,DOCK9,TMEM151B,FRYL,GZF1,MTMR14,TK2,ZFP91,TNS1,AMACR,RUSC1,TSC1,SSBP2,AMOT,MGAT5B,MTCH1,XPO1,ZNF24,TRIM9,SLC26A10,LYPD6,DPYSL5,SYNC,MEIS3,DHX33,CSDE1,PCDH15,URM1,SLC17A7,WNK3,SLC17A6,EPM2A,ACTR3B,RNF170,SOCS4,LAS1L" MicroRNA hsa-miR-1245:mirSVR_lowEffct hsa-miR-1245:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.81E-136 1.02E-132 2.71E-135 2.50E-134 342 1396 "RALGAPA1,ADCY6,SLC12A5,RNF150,INTS2,WDR35,AK2,HFM1,SEMA6A,ALCAM,MAP4K3,PPFIA1,PARG,APAF1,APBB1,UPRT,GPAM,SHTN1,ARSE,ATM,B3GALT2,DPY19L3,ADAM23,ADAM15,LINC00847,DCAF5,NRP2,CFLAR,BMPR1B,ARHGEF7,FUBP1,C1QC,CDK5R2,CACNA1B,CACNB2,CACNB4,DIRAS1,CALM1,PTBP2,CAMK2D,CAPN3,VSTM2A,CH25H,MAP7,METTL6,CD86,CDC27,ZBED1,CDH8,CDH10,CCPG1,NUMBL,SRSF11,B4GALT6,KMT2C,RAB33A,NRXN3,CLCN3,NGEF,FAM189A2,SRP14-AS1,NIPBL,FHL5,CNR1,PCYT1B,FAM149A,ZNF521,CREM,CRMP1,NCOR1,GDA,ABCG1,SNCAIP,TENM4,SEC24C,OSBPL3,CNTNAP2,FAM169A,SLITRK5,UBXN2A,PHF14,GREB1,CCDC144A,HDAC9,ARHGAP24,LONRF1,TBC1D5,DGKB,TOMM20,PABPC5,GIT2,C8orf34,ZEB2,MYEF2,DDX46,SNAP91,SPOCK3,KIF19,SEC16A,DMPK,FAM78B,DNM1L,ABCC9,EDNRB,ATL1,SEMA3D,RBM12,SH3GLB1,ASB3,ELN,EML1,USPL1,EN2,EPHA5,KCNMB2,ENPP6,SLC43A2,EYA1,NSRP1,FABP7,FCGR1A,CHST15,ZSCAN30,FDFT1,FECH,FER,GTF2IRD2,FGF1,FGF11,FGFR1,PRKAG2,MEX3B,TMEM107,USP21,CAMKK2,CGREF1,STAU2,ZNF512,NEURL4,MEGF10,GABRB1,FAM120B,B4GALNT1,JPH4,ARPP21,IQGAP2,ERAP1,PCDH17,RUNDC3A,CRCP,TOX3,PCDH11X,FERMT2,LNX1,GPD1,STON1,NUDT21,CNTRL,GRIA1,GRIA4,GRM1,LINGO1,GUCY1B1,WIF1,MAEL,BACH2,HMGCL,AGBL5,HNMT,OPALIN,ATCAY,ZNF546,C5orf24,LIX1,DIPK1A,KCNA1,KCNB1,KLHL23,KCNK2,CREG2,LMO2,HECTD2,MBNL1,SYT9,CHIC1,MEIS2,MMP16,MOG,ERICH3,MYCN,NEXMIF,ZC3H12B,CCDC13,SLCO1C1,NODAL,NOVA1,NPTX1,SLC11A2,KCNK10,PAK3,CNTN3,PAX6,PBX1,PCDH9,PCSK5,PDGFRA,GNG2,NLGN3,SNX10,ZNF426,MTRF1L,PMP22,STRN3,RC3H2,PSAT1,PRRX1,NXPH1,PPP2R2C,PTPA,PPP2R5E,MAPK4,MAPK9,MASP1,CNNM2,MDGA2,CNTLN,UHRF1BP1,MTMR10,PTN,EML5,PTPRH,FAM120C,ACSM5,USP47,FAT4,RASGRF1,FEZF2,ZYG11B,RFX4,CARF,ROBO1,TMEM100,MCMBP,GLDN,ADAL,HSD11B1L,NCBP3,ZNF331,SALL1,HOGA1,SCN8A,SOX6,SLITRK3,NLGN1,ANKRD6,ZNF365,SEPHS1,SLC8A3,SHANK2,SPHKAP,TET1,GKAP1,SMARCA4,SMARCE1,RCOR3,LIMCH1,SNRPN,TMCC1,FAM126B,KDM4B,KIF21B,ZSWIM8,SPP1,PEG10,ATP10B,CLASP2,POGZ,SSTR1,EPB41L3,NXT2,STX1A,ABCC8,NUDT10,PLCB1,SYN2,UNC5D,DMXL2,SATB2,ZEB1,WDR7,SYNE1,AKNA,PUM2,PCDHA1,FRYL,DICER1,SIRT1,DICER1-AS1,ZFPM2,HHIP,ARL10,MTMR14,TLR4,LRRC8A,FAM124A,R3HDM1,PIK3R5,TPD52L2,TPM4,SYNPO2,TRPC1,CA14,SSBP2,RFTN2,UBE3A,PITPNB,BCL2L13,SLC13A3,XPO1,ZBTB14,EMSY,STOX2,PRDM8,LMAN2L,VPS35L,PCDH15,SLC17A7,FAM47E,WIPF2,SLC17A6,PARP11,ST7,UBE3B,PAK5,PHTF2,NUP214,TIGD6,SSPN,NETO2,SOCS4,SPATA13,JPH3" MicroRNA hsa-miR-3123:mirSVR_highEffct hsa-miR-3123:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.94E-136 1.65E-132 4.41E-135 4.06E-134 355 1505 "RALGAPA1,TTYH1,CCDC85A,GALNT13,ADD2,BRAP,SORCS1,KIDINS220,KLHL13,RTL9,HACE1,ADGRF5,C1QTNF3,LRRC7,SMIM17,ALCAM,ARHGAP20,MARCH4,UNC79,OGT,LRCH2,APP,AQP4,MIER1,ASPH,ZBTB10,NUMB,ATM,SLC4A4,ZNF583,BACH1,CFLAR,WASF1,CALM1,PTBP2,SLC25A14,VXN,USP2,INA,CD86,TMEM257,DGKI,MAGI1,TIGD7,COPB2,CASC2,MS4A7,SYNPR,RAB28,NRXN3,PLAA,KIAA1549L,NRXN1,TPP1,MAP4K4,NIPBL,TMEM155,CNN3,CNTFR,AKAP6,SUMF2,LETMD1,COL9A3,BAG4,CLOCK,CLIP3,ARHGEF10,ATRNL1,SOCS5,PDE4DIP,ERC2,NRSN1,RIMS2,RUBCN,DOCK4,TCAF1,DCAF8,DGKB,TMEM170A,PABPC5,DBN1,ZNF804A,C8orf34,MYEF2,C2CD2L,BLOC1S6,ZNF582-AS1,DLG2,DMD,DYNC1I1,SLC12A6,ABI1,PDCD6IP,DTNB,ABCC5,DNM1L,ABCC9,GOLT1B,E2F6,EDNRA,YAF2,SH3GLB1,PHF20L1,EGFR,ELN,TUBD1,VPS13B,EPB41L2,KCNMB2,ETV1,PIPOX,TLR7,SIRPB1,NRN1,FAM198B,ACSL4,CEP78,FGF11,FGFR1,FGR,FLT1,ANKFY1,C2orf88,TACC2,PDLIM5,ATP2C1,CELF1,STAU2,FYB1,STAG2,GALC,IQGAP2,ERAP1,ATP8A2,TUBGCP4,SULT1C4,ADAM28,GHR,GLRB,GNAL,GNAS,PSRC1,GOLGB1,GPM6B,FUT10,CNTRL,DIDO1,PLCD4,GRM5,GRM7,COQ10A,SOX21,RNFT2,WIF1,MAEL,HAS2,LINC01102,HLF,GABARAPL2,SHISA6,HTR2A,HTR5A,PLD5,SCIN,IL11RA,ZNF385B,LRRTM3,ITGAM,JAK1,SLC35G1,KCNA1,OLFM3,KCNK2,KIF5C,FGFBP3,PIK3AP1,MAP2,MDM4,MEIS1,MEST,MOBP,MRPL42,SESN3,ADAM22,MTTP,LYRM9,MYO6,PABPC1L2A,NAP1L2,NCAM1,NDP,NF1,NRCAM,SMIM11A,NTRK2,OCRL,GPR137C,SNTG1,PBX1,PCDH9,PRTG,GPR173,BEST3,ZDHHC8,GPSM2,JAKMIP1,PLP1,MTRF1L,LRP12,POU3F2,PPP2R5C,PPP3CA,PRKACB,RAB39A,PKN2,HYDIN,DIRAS2,RELN,CNTLN,MTMR10,TMEM260,STK32A,FAM120C,PEX5,PPP2R3C,ZNF793,ZNF493,OXR1,RASGRF2,DBX2,KHDRBS2,RDX,SLC6A15,RFX3,SLC25A36,NUDT11,RNASEL,ZNF532,RERGL,C12orf49,CCDC102B,NEK11,UEVLD,MCMBP,GLDN,LRRK2,ABCA11P,SOX8,KCNIP1,CCDC112,AP1AR,DGLUCY,FAM19A1,PRCD,FNIP1,ASIC4,NLGN4Y,PPM1E,HKDC1,CHD9,FBXO11,R3HDM2,ST6GAL1,BCAN,CTXN2,ZNF365,EPN2,DHX30,SMTN,SLC6A9,SEPHS1,TMEM132D,EFHD1,ATF7IP,SLC22A4,SORCS3,LIMCH1,MBD5,FAM126B,SP4,SPP1,NPAS3,NFASC,C11orf87,SRPK2,CLASP2,SMOC1,SSTR2,ZC4H2,NEK4,STXBP1,PRRC2C,ARHGEF9,PLCB1,TACR1,CAMSAP2,FAM208A,UNC5D,ADGRL3,TBCEL,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SPX,C18orf54,HHIP,GZF1,TMEM9,TJP1,HEY2,TMPO,KAT6B,PIK3R5,TP53BP2,TPM4,METTL3,PRMT8,TRH,TRIO,TRPC1,ZMYND8,FAM155A,BCL2L13,MEAF6,CCDC14,GUSBP1,KCNT2,TRIM9,AGMO,LAMP5,SYNC,WNK1,EMSY,LINC02210,STMN4,PCDH15,NAV2,PPP1R3F,PLSCR4,FAM13C,FZD3,DOCK8,KAT6A,CERS6,JMJD1C,ZNF248,KLHDC1,NETO2,CBLN2,SLC4A10" MicroRNA hsa-miR-603:mirSVR_highEffct hsa-miR-603:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-136 1.98E-132 5.27E-135 4.85E-134 343 1407 "GALNT16,ADD1,ADD3,PTCHD1,KIDINS220,BEND6,INTS2,KLHL13,TAOK1,SMIM17,ARHGAP20,AMPH,OGT,ANK2,EP400,PKP4,ANXA7,PARG,EPB41L5,CACHD1,BCAS1,TNRC6C,SHROOM2,AQP4,MADD,TMEM263,CASK,ARHGAP5,NCOA1,NUMB,ASTN1,DYNLL1,TMEM108,ATM,ATP1B3,ATP2B1,NOL4,MPDZ,PROM1,BMPR1B,CDK5R1,SYNJ2,FUBP1,NAE1,OSGIN2,WASF1,CACNB2,VXN,SYT6,SPAG9,KRIT1,METTL6,INA,CDC27,CDH2,CDH10,MAGI1,TIGD7,CFL2,SRSF11,SOCS6,CHN2,NRXN1,QKI,HECTD1,RAB26,ARHGEF6,AHCTF1,ZFP28,CPS1,SEC31B,RBM39,ANKRD44,GDA,SEC24C,FEZ2,FEZ1,CSNK1G3,PLXNA4,PITPNM3,PHF14,CFAP61,CTNND1,NRSN1,ST18,USP6NL,LONRF1,LIN54,MATR3,KIAA0586,TMEM170A,DAPK1,TOMM20,SPATA2,YTHDC1,C8orf34,HP1BP3,KIAA0319,MED24,NTM,SGSM2,KBTBD11,DMTF1,CASP8AP2,DPYSL2,ARRDC4,ECM2,MAMLD1,DYRK1A,E2F6,EDNRA,SEMA3D,FSD1L,PHF20L1,GOLGA7,PLEKHA1,SRPK3,PCOLCE2,TMEM35A,CALCRL,EN2,EPHA5,RAB9B,MRPL37,TLR7,NSRP1,SH3YL1,ACSL4,GTF2IRD2,FGFR1,FGR,AMOTL2,SUCO,SEC23B,IP6K2,SYNCRIP,RGPD5,PSD2,NBEA,NSG2,DACH2,NSG1,STAU2,MEGF10,GAA,HRASLS5,GAP43,DNER,GCNT2,SESN1,PCDH17,GGTA1P,HPGDS,GLS,MSL3,ZNF638,KDM2B,HTATSF1,KCNMB4,ZNF782,GPR34,NUDT21,GRIA1,DIDO1,GRIK1,NR3C1,GSN,RNF165,PSIP1,WIF1,MAEL,RASSF8,MSL1,ZNF181,RBPJ,ITGAV,KCNA2,KCNK1,KIT,STXBP5,L1CAM,INSYN2,SYTL4,PIK3AP1,LDLRAD3,POC1B,AFDN,BLOC1S2,MSR1,MYO9A,NAP1L3,P2RY13,NCAM1,NF1,NPY,LRIT2,SETD4,GPR137C,PCSK2,PDE3A,NALCN,RETREG1,FAM216A,PLCL1,ING3,RETREG2,MINDY2,PTPA,PPP2R5C,CEP41,PKIA,HYDIN,SIDT1,SNRK,MDGA2,PTHLH,PTPRD,PTPRG,PTPRN,PEX5,CEP97,TMEM255A,USP47,RAD17,PLEKHB2,SH3TC2,FAM184A,ZNF493,RADX,RDX,RET,FIGN,RGS4,SEC61A2,RIC8B,NUDT11,PBRM1,RAVER2,CARF,CCDC102B,FBXW7,LRRK2,LGR4,ZNF354C,NCBP3,AP1AR,SALL1,SATB1,ATXN2,ATXN7,SCN2A,LINC00461,SCP2,SELL,SH3GL2,FHOD3,NLGN1,SEC31A,SLA,ZNF365,SMTN,ATF7IP,SMARCE1,SNAP25,MBD5,PALLD,TMCC1,UNC80,USP33,SP4,PEG10,ZC3H13,CDK19,RBM26,SPART,ZC4H2,ERBIN,ELOVL4,SEPT8,TTBK2,SYNE2,PLCB1,COBL,MMS19,TACR1,PJA1,CAMSAP2,AGTPBP1,TBCEL,TMEM136,TCEA1,SATB2,ZEB1,WDR7,SLC19A3,PCDHB6,PCDHB3,AP4E1,SLC44A1,GZF1,ASXL3,TMPO,PRRT1,CSMD1,ZNF384,RGMB,NR2C2,TRPC1,ANKRD20A2,TTC3,SGK3,RPL7L1,EIF4ENIF1,USP1,VGF,WIPF1,GUSBP1,ETNPPL,SF1,PCDH20,ZBTB14,FMN2,MKRN3,LYPD6,CELF4,ZBTB38,FSTL5,PLPPR5,UPF3A,PMEPA1,CADM2,LRP8,SCG2,PCDH15,FIP1L1,PLSCR4,PARP11,DOCK8,PHTF2,ZNF248,SLC39A12,IFT88,RNF146" MicroRNA hsa-miR-128-3p:TargetScan hsa-miR-128-3p TargetScan 4.42E-136 2.48E-132 6.58E-135 6.06E-134 273 882 "CPNE2,ELFN2,ADCY2,ADCY6,ADD2,PLEKHH1,PTCHD1,MTA3,KCTD16,AK2,PITPNM2,ANK2,PPFIA2,APBA2,GPAM,PDE8B,NCOA1,ALDH4A1,ATP2B1,RNF182,NOL4,DPY19L3,DOCK11,NRP2,KSR1,DST,FUBP1,CA12,CACNA1A,DIRAS1,PTBP2,BRSK2,C1orf52,DGKI,LRRFIP1,FOXN3,KMT2C,DLGAP3,PLAA,CLCN3,KIAA1549L,NRXN1,QKI,HECTD1,NIPBL,IGLON5,CNN3,CNR1,ARMC8,CABP1,COL11A2,C2CD2,HAPLN1,CSF1,NCAN,ERC2,CTH,HDAC4,LONRF1,RIMS3,DCC,PLEKHM1,ELMO1,KBTBD11,DLG2,RAB39B,CALN1,NR1D2,CDON,DRP2,ARRDC4,DTNA,E2F6,PHC2,HIPK3,FEM1B,EFNA2,FAM13A,GPR61,EGR3,PLXNC1,EIF5,ELAVL2,RGS17,EML1,EN2,EPB41,EPB41L1,EPB41L2,RCAN2,MTSS1L,EYA1,F3,REEP2,CACNG2,ATP8A1,MED12L,KIAA1109,FGF14,ANKFY1,FUT9,DOT1L,MPP6,BRSK1,NEURL4,MEGF11,GAB1,GABRB1,ILDR2,GAD1,BRPF3,ARPP21,NEK6,FAXC,GCNT2,CSDC2,GHR,PPARGC1A,GPR75,KCNMB4,GPD2,CECR2,GRIA1,DIDO1,GRIK3,GRIN2D,GRM5,PTPRT,KIF3A,PTPN5,KAT7,MAP4K5,FAM222A,MIER3,HNF4G,AGFG1,MSL1,IGF1,INSM1,METTL21A,KCNA1,KCNA4,KCNA6,KCND3,KCNJ3,KCNK2,KCNN3,KPNA5,LIFR,MSANTD3-TMEFF1,ARHGAP12,NCOA7,LSAMP,MAN2A2,MATN3,MDFI,CHIC1,LDLRAD3,MDM4,MEIS2,KITLG,MN1,MPP2,MSI1,MDGA1,MXI1,MYT1,NCAM1,NF1,NFIA,NFE2L2,ALDH1L2,NOVA1,NPTX1,NPTX2,OPA1,KCNK10,PAX6,PCDH9,CDK18,PDE3A,PDE3B,PDE1B,PDGFRA,PDPK1,PIK3C2A,PIK3R1,CDIP1,MED1,RASGEF1B,PKIA,MAPK10,DIRAS2,RELN,CNNM2,PTPRB,RAD51D,FAM184A,RET,FIGN,RFX3,KLHDC8A,ALG9,CYB561D1,ROBO1,RORB,FBXW7,HUNK,RXRA,FAM192A,AMER2,CASC3,FAM102A,PPP1R9A,PPM1E,ARX,CPEB3,MAGI3,CCDC92,CCDC88A,CPEB4,RCOR3,MBD5,FAM126B,SCN3B,KDM3A,PEG10,NPAS3,NFASC,C11orf87,ATP10B,CLSTN2,POGZ,COLGALT2,LARP4,NXT2,MAPK8IP3,ELOVL4,MCF2L,PDLIM2,CNTN2,SATB2,RPGRIP1L,NSD1,CRTC1,GPRIN3,FRYL,NACC2,CBX5,DDHD1,RASD2,PRMT8,CADM1,FAM155A,GORASP1,PLEKHH2,BCL2L13,KCNK12,MICU3,DPYSL5,CA10,NAV3,NAV2,KCNAB1,MVB12B,FZD3,MARCH8,KAT6A,JMJD1C,ADAMTS10,NETO2,NETO1,RNF146" MicroRNA hsa-miR-4299:mirSVR_lowEffct hsa-miR-4299:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.56E-136 3.12E-132 8.26E-135 7.61E-134 381 1730 "TTYH1,SERPINA3,KCNH8,ASIC2,SYS1,ACTN1,CSMD3,FMNL2,PLEKHG5,ADCY2,GALNT13,ADD2,ERMN,UNC5A,RNF150,BEND6,AP1B1,CC2D2A,TAOK1,C1QTNF1,SPARCL1,PCDH10,BBOX1,ZFAT,CDC42BPA,ANK1,FGD2,SUGT1P4-STRA6LP-CCDC180,KCNAB2,ALS2,NT5C3B,AMER3,USP37,LGR5,CDK10,ARHGAP5,PLA2G4C,ZSCAN18,NUMB,ATM,NOL4,DPY19L3,ADAM23,BACH1,ADGRB3,BBS2,SYNJ2,ARHGEF7,SCAPER,CASTOR3,SGCE,CALB1,KALRN,PTBP2,CAMK2G,SHISA7,LDB2,CCKBR,CD38,ARHGEF2,CDC42,CDH2,CDH8,LRRFIP1,L3MBTL4,CHGB,ASIC3,CHN2,CHRM1,CASC2,SYNPR,NDST3,KMT2C,MAP4K4,AKAP5,COX4I1,TOGARAM2,PNKD,CDC42BPB,AKAP12,HINFP,CSF3R,FEZ1,SUSD5,VCAN,NCAN,PPP1R16B,PLCXD3,CTH,ZSCAN23,DCAF4,ECE2,ARHGAP32,FGFR1OP2,KIAA0513,TM9SF4,SPATA2,ZNF804A,ZEB2,ELMO1,MFAP3L,HP1BP3,RUSC2,TMCC2,WDR20,CHRDL1,GRIN3A,CD99L2,RPS6KL1,DPH1,DPYSL2,ACOT8,DRP2,PDCD6IP,DNAJB6,RBM12,EGR3,COPS4,PLEKHA1,ELN,EML1,VPS13B,MFSD10,EPHB1,KCNMB2,SRRM1,EPS8,TLR7,RASL12,MRVI1,EZH1,TAOK3,CORO2B,FCGR1B,ST3GAL6,CEP78,TESK2,SEC24B,FER,PRKAG2,POLK,FOXO3,FLT1,NELFCD,FOLR2,TMEM175,TRMO,POMT1,UFM1,PDLIM5,KHDRBS3,STAU2,MEGF10,CHL1,GAD2,ZMYND11,ARPP21,IP6K3,ATP8A2,CPLX1,PCDH17,MALT1,BRD8,RND1,CRCP,TCERG1,COPS8,TNRC6A,POLL,KCNMB4,DCLK2,LOXL3,GPR12,GPR22,TMEM121B,PCLO,RAPGEF1,GRIA4,GRIK1,GRIN2D,BTN2A1,PTPN5,TMEM25,KAT7,RNFT2,GUCY1A1,GYG1,PADI2,SYNPO,HMGCL,OPALIN,SHISA6,CELF5,SMAP1,IDH3B,LINC00667,C2orf72,LRRC25,GAREM2,RBPJ,LRRCC1,KIAA1755,SCIN,LIX1,IL6R,BRINP3,ZNF678,INPP5B,KCNC2,KCNJ3,KCNJ16,KCNMA1,STXBP5,FGFBP3,MAN2A2,MAPT,MBP,SYT9,TM6SF1,MEIS1,MID1,MPP2,ERICH3,CCDC80,BLOC1S2,MYO6,NCAM1,NHLH1,OGG1,ZNF713,GLIPR1L2,SNTG1,PAK3,CNTN3,PDE3A,PDE3B,PFKFB2,ZNF655,PRIMPOL,PRKCB,RAB39A,PRKCZ,CNNM2,SIDT1,MDGA2,CNTLN,ANKHD1,BDNF-AS,PTPRB,PTPRE,ZSCAN2,RALGDS,IQSEC3,ZCWPW1,ENOX1,OXR1,RASGRF1,RASGRF2,BSDC1,ERI2,GTDC1,RFX4,SEC61A2,RIC8B,RNASEL,LGI2,CCDC82,ROBO2,ATP8B4,ADAL,CNTNAP3,LGR4,RPS20,RTKN,ZNF331,FAM182A,SEMA6D,ATXN7,SCN2A,LRRTM4,PRCD,TNFRSF19,GALNT10,PPP1R9A,SH3GL2,KIF16B,FNDC3A,ST3GAL3,ZNF365,RPH3A,SLC2A5,PEX26,SLC8A1,KBTBD4,SCMH1,CPEB4,ARFGAP1,EPC1,GKAP1,ANKRD36,LIMCH1,RIMS1,SNRPN,PALLD,FAM126B,USP33,SCN3B,WDTC1,DOK5,NMNAT2,ZNF423,SPTAN1,IQSEC2,TSPYL2,DDN,SPART,NFASC,SMOC1,ZC4H2,NKAIN2,SEPT8,RGL1,ADHFE1,KANK1,SULF2,SYNE2,VAMP1,PLCB1,SYN1,ARC,TACR1,KAZN,WWC1,EHBP1,ACSL6,TCF4,SIN3B,TPCN2,TRIM2,AZIN2,NAT16,DOCK9,ARHGAP9,SIK3,ITGB3BP,AP4E1,AKTIP,ZFP91,NR2E1,FAM124A,RBFOX2,RASD2,C9orf85,ZNF346,PRMT8,ELP5,TRPS1,LRTM2,CADM1,UBE3A,OSBP2,WRN,CLDND1,SF1,ZNF711,ZBTB38,POLR3H,LAMP5,CA10,PMEPA1,EMSY,PRDM2,SLC38A1,CSDE1,STOX2,SLC17A7,MPPE1,WNK3,MVB12B,JMJD1C,FXR1" MicroRNA hsa-miR-153:mirSVR_lowEffct hsa-miR-153:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.72E-136 3.78E-132 9.96E-135 9.17E-134 367 1610 "ASIC2,EMILIN3,ARID1A,XKR4,CSMD3,NDRG3,FMNL2,ADCY2,DSCAML1,ADCY6,ADD1,AXIN2,USP31,PWWP2A,PTCHD1,BEND6,WDR35,ZNF578,SMIM17,CARNS1,UNC79,BEGAIN,AMPH,ANK3,CCDC146,APBB2,UPRT,DDO,SHTN1,AQP4,MIER1,CASK,TMEFF1,SPTBN4,ARHGAP5,ARNTL,ATP2A2,NOL4,DPY19L3,DOCK11,ADGRB3,LINC00906,CACNA1G,CACNA1B,CACNA1D,DDR1,CACNB4,CALB1,CAMK2G,CANX,CH25H,RUNX1T1,ARHGEF25,CBR1,CLDN10,LDB2,SCARB1,DGKI,AP4M1,CDC27,LGI1,CCPG1,SRSF11,CHM,MS4A7,SYNPR,CNOT8,CLCN3,CLCN4,CLTC,CNGA3,AKAP7,IQCK,ARMC8,SLC4A7,AHCTF1,ZNF521,ZFP28,MFSD4A,C2CD2,RBM39,ANKRD44,RGS6,SOCS5,SLITRK5,APPL1,USP6NL,SNPH,PABPC5,BRINP1,DCC,ELMSAN1,ZEB2,PLEKHM1,COPS7A,CEP170,PLPPR4,SACS,DLX1,EXOG,USP3,CDON,CPEB2,DNAJB6,ABCC9,EDN1,FAM135B,ANKRD46,KLHL5,TMTC1,FSD1L,PHF20L1,ABI2,PLEKHA1,RGS17,PAN3,VPS13B,KCNMB2,GPHN,NCALD,KATNAL1,CLVS1,ATP8A1,RACK1,CHST15,FER,FGF12,POLK,ATP13A4,SLC37A3,TACC2,SORBS1,PDLIM5,TPK1,ATP2C1,ZNF605,KHDRBS3,DACH2,STAU2,DOT1L,MEGF11,GABRA1,TRAF3IP2,GAD1,HBS1L,BRPF3,NEK6,SULT1C4,PPARGC1A,KDM2B,HTATSF1,RAB40B,FERMT2,PRUNE2,GPM6B,LPAR4,RAPGEF4,GRIA2,PLCD4,ADAMTS8,GRM5,RNF165,TMEM25,MFSD2A,AP4S1,PSIP1,CELF3,HAS2,ARHGAP19,DDX19B,MIER3,IGFBPL1,HNRNPK,SMAP1,IRF8,ZNF181,C5orf24,RBPJ,KIAA1755,SCRT2,INSM1,KCNA4,KCNA6,KCNB1,KCND2,KCNH2,KCNK1,STXBP5,LIG4,PAXBP1,LMO2,HECTD2,PACRG,AQP11,SHC3,MEIS1,SCAMP5,MITF,MKLN1,CTNNA3,PABPC1L2A,NDUFA5,NEFM,NEFH,NF1,NFIA,CNOT4,NPR2,SLC11A2,HCN1,NTRK3,OMG,OPHN1,CLDN11,GLIPR1L2,SNTG1,PCDH8,PDE3B,PDE4D,PDYN,GPR85,GNG2,PFKP,ANLN,PIK3R1,FAM216A,PURG,PDZRN4,MAPKAP1,SCHIP1,PRRX1,ING3,SEPT4,DRAM2,PPM1B,CRLS1,PPP2R5C,PPP2R5E,PPP3CB,PRKAB2,PRKACB,PKIA,MAPK4,GRAMD1C,DCHS2,MASP1,VPS13C,LRRC49,MDGA2,ANKHD1,MTMR10,PTPRB,TUG1,RAD51D,FAT4,ARID4A,REV3L,TTLL7,KIF7,SLC25A36,ZFHX4,LGI2,CCDC82,RERGL,TMLHE,ROBO1,SNX22,ARMH4,UEVLD,BAALC,GLDN,CNTNAP3,ATAT1,KCNIP2,STX1B,AMER2,SCP2,SLC30A10,SCAF8,DOCK10,CHD9,FBXO11,ST3GAL3,ZNF365,KANSL3,SLC8A1,ELMO2,SLIT1,CPEB4,EPC1,SORCS3,LIMCH1,SNCA,LMBRD1,PALLD,MYO16,USP33,SOX2,BDP1,SP4,HECW1,ZNF423,TSPYL2,NPAS3,SRPK2,TAB2,ITPRID2,ZSCAN29,SEPT8,TTBK2,KANK1,NSFL1C,NECAB1,SYNE2,SYN2,SYPL1,SYT1,SYT4,ATP11A,AGTPBP1,EHBP1,TCF4,ZFP90,CUX2,RPGRIP1L,WASHC4,WDR7,AZIN2,DOCK9,PCDHB10,USP32P1,HIF3A,TEK,DICER1,SIRT1,HEY1,ASXL3,DDHD1,FAM124A,RGMB,SMUG1,TRIO,DCBLD1,TSN,RPL7L1,PLEKHH2,VLDLR,ZNF711,ZFAND5,SLC30A3,LRP8,STOX2,PRDM10,TUBA1A,NAV3,TMEM163,WIPF2,EPM2A,RTN4,UBE3B,FBXO36,ADAMTSL3,NHSL1,FXR1,IFT88,SLC4A10,SPATA13" MicroRNA hsa-miR-1302:mirSVR_lowEffct hsa-miR-1302:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.56E-136 4.25E-132 1.12E-134 1.03E-133 357 1526 "ACADM,KDM5D,FAM43B,ARID1A,SLC25A25,NDRG3,NDRG2,ADARB2,TMEM132B,ADD2,PTCHD1,FAHD2CP,NLGN4X,C1QTNF3,ALCAM,PCDH10,KCNT1,EP400,FGD2,CCDC146,LCORL,PPFIA4,PHF12,PPFIA1,DDO,VAT1L,API5,SHTN1,LGR5,AQP4,CDK10,SFMBT2,SEMA4G,IGDCC4,ARHGDIG,ARRB2,ASPH,BRINP2,SLC4A4,SLC2A11,ALDH7A1,CADM3,ATP6V0A1,KIF1A,ADAM23,MPDZ,SEC11C,RGS11,RGS9,BID,CFLAR,AP1M1,NIPA1,CACNA1E,CACNB2,CACNB4,TRIM41,CARS,SPAG9,METTL6,USP6,AP4M1,CDC25B,CDC42,TIGD7,CCPG1,NOG,DIS3L,ADGRG1,PLEKHB1,MAP4K4,TMEM155,FHL5,IQCK,AKAP6,SUMF2,TBPL1,SMARCAL1,MFSD4A,NECTIN3,SLC35F1,AKAP12,CRY2,SNCAIP,OSBPL3,VAC14-AS1,PDE4DIP,PITPNM3,ERC2,EDRF1,KIAA0408,BOC,ARHGAP32,DCAF8,CENPL,GIT2,ELMSAN1,RUSC2,C2CD2L,BLOC1S6,POM121,SMG7,DLG2,DMD,SLC29A4,CDON,DPH1,PDCD6IP,MAMLD1,E2F6,PHC2,PHF20L1,SUGP2,TNK2,C3orf18,CALCRL,DCTN4,ENO2,EPB41L1,COQ7,LRRC17,RAB9B,IGSF6,CEP85L,ZNF549,MRPL37,EZH1,NSRP1,TBC1D16,TAOK3,DLC1,CHST15,FKTN,MED12L,KIAA1109,FGF14,IP6K2,EVL,PSD2,NELFCD,C2orf88,EFCAB2,SORBS1,UFM1,ATP2C1,ERGIC3,CELF1,NRG3,FYN,STAG2,GABRA2,GABRB3,TRAF3IP2,DENND2A,GAD2,HBS1L,GCK,ALDH1L1,GCNT2,GFAP,PPARGC1A,GK,ZNF276,COPS8,GPT2,ADGRA3,GPD2,GPM6A,DIPK1C,LILRA1,GPR22,RAPGEF4,ADAMTS13,CACFD1,GRM2,GRM5,GRM7,KIF3A,ZBTB49,AP4S1,SLC2A6,ATOH8,IRAK3,PADI2,ATXN2L,HTR2A,ICA1,MSL1,LINC00667,C5orf24,LRRCC1,DISP2,USP54,IGSF1,ITGA7,METTL21A,KCNJ3,KCNK3,KCNMA1,KCNN3,CREG2,KIF5C,TTYH2,MAP4,ADAM11,MEIS1,MEST,KCTD6,SCAMP5,AFF1,MN1,DBNL,MSI1,RSPO2,ZNF862,FXYD6,NHLH1,NNAT,NOVA2,NUCB1,OGG1,OLR1,OPHN1,P2RX7,PAX6,PC,PDE4A,GPSM2,FAM216A,FTO,PURG,PNMA3,EXOSC10,SCHIP1,PRRX1,ING3,RETREG2,SEPT4,FAT3,FSD1,PCDHB17P,PRKCG,GRAMD1C,PTCH1,ANKHD1,PTPRD,PTPRE,CASTOR1,PTPRN,CEP97,FAM66C,ATG16L1,NWD1,RASGRF2,PRIMA1,SETD5,ARMC5,ROBO1,RPE,FBXW7,KIAA0895L,MCMBP,ADAL,LGR4,ST6GALNAC6,WLS,ZNF354C,DGLUCY,ATXN7,HOGA1,SCN4B,PRCD,SCP2,ASIC4,PEAR1,TRIM46,STUM,SFPQ,SHC4,FNDC3A,PEX26,NAPB,NAXD,SORCS3,SMARCD3,INAVA,CABCOCO1,FAM219A,PDZD2,BDP1,ZSWIM8,ZBTB43,NPAS3,ATP10B,SSTR1,ZC4H2,LARP4,STAC2,ADHFE1,FGD4,SYN1,SYN2,COBL,TAC3,SEMA4A,DDHD2,PDLIM2,TBX15,SATB2,RPGRIP1L,TCF12,WDR7,NAT16,PUM2,USP32P1,AHCYL2,CYB561A3,FAM200B,C18orf54,FAM124A,TNNT1,TNS1,TPM1,C9orf85,TTTY15,RFTN2,RPL7L1,UBE3A,VLDLR,P2RY12,CLIP2,NSD2,RICTOR,GUSBP1,ZIC3,NDRG4,LYPD6,SPIRE1,SYNC,EMSY,PRDM2,PRTFDC1,DNALI1,GDPD5,SCG2,FIP1L1,ITM2C,WIPF2,SLC17A6,GOPC,FBXO36,NUP214,JMJD1C,ZNF248,FRMD6,IFT88,SPATA13" MicroRNA hsa-miR-644:mirSVR_lowEffct hsa-miR-644:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.57E-136 4.81E-132 1.26E-134 1.16E-133 344 1419 "ASPHD1,ABHD6,SYS1,ADCY6,ADORA3,DPY19L2P4,ZNF608,SNX32,HACE1,KIAA1324,OSBPL6,TXNDC16,USP35,CEP126,AMPD2,KIF6,LRFN1,ZFAT,MAP4K3,PPFIA1,CNTNAP1,DGKZ,UPRT,ALS2,SEMA4G,PLA2G4C,ARSE,CADPS,PCDHGB4,ALDH4A1,CHID1,ATP1A1,ATP1A2,CADM3,ADAM15,KALRN,VXN,LDB2,USP6,CD86,CD38,SYNPR,CHRNA4,B4GALT6,KIAA1549L,CLTC,FAM189A2,TJP2,VAX2,SULT4A1,SRP14-AS1,IQCK,PCYT1B,MAGED1,ABI3BP,SLC35F1,SNCAIP,SEC24C,CHD5,VAC14-AS1,PDE4DIP,GREB1,NRSN1,KATNAL2,PABPC5,ZEB2,HEPH,RUSC2,COPS7A,PLPPR4,AK5,SGSM2,TMCC2,ARNT2,SEC16A,DNM2,CPEB2,SLC12A6,GNE,DUSP9,DNAJB6,ABCC9,USH1C,EDN1,EDNRA,ANKRD46,HEYL,ASB3,EIF4G2,TENM1,ELAVL4,RGS17,EN2,MTSS1L,RAB9B,SRRM1,NCALD,CDHR1,VPS26C,ARMCX1,SH3YL1,DLC1,ZNF589,FGF11,FHL1,CAP2,FLT1,SYT3,ERGIC3,KHDRBS3,CGREF1,GABRA2,CAB39,BRPF3,ZNF559,ATP8A2,NEU3,GBX2,ALDH1L1,GFAP,ADAM28,BRD8,TNRC6A,KDM2B,MAP7D2,RAB40B,TDRKH,GPR17,GPER1,DIDO1,GRIA4,GRIK2,ADAMTS13,SERP2,GRIN2D,NR3C1,ZNF496,LINC01551,FAM107A,GUCY1A1,CELF3,PADI2,MIER3,NEGR1,OPALIN,HSF2,SHISA6,SMAP1,ATCAY,MYLK2,ZIC5,RBPJ,KNDC1,SCIN,IL6ST,INSM1,C2CD4C,KCNJ11,KCNK1,KCNK2,LINC00634,KLC1,HECTD2,LOC100128239,ZFYVE27,MAP6,MBNL1,SYT9,MEIS1,MEIS2,XRRA1,GIT1,BCO1,MSR1,MT3,N6AMT1,MTTP,RSPO2,MXI1,MYO7A,RTL5,NEXMIF,MYT1,FXYD6,ALDH1L2,NHLH1,NPR2,SLC11A2,SMIM11A,TBC1D25,OPCML,OPHN1,LOC100128398,PCDHGC3,PCDH9,PCMT1,PDE1A,ENPP2,PDPK1,PFKFB4,ST8SIA5,PLIN1,HMGCLL1,PLXNB1,RC3H2,PRRX1,POLR2F,PPARA,PPP3CA,PRKAB2,CEP41,RAB39A,HYDIN,MASP1,BCAS3,GDPD2,TMEM104,CNTLN,ELOVL2,PTK2,ACSM5,NKAIN1,RASGRF2,DBX2,ZDHHC14,ZMAT4,MORC4,GTDC1,RGS12,ARHGEF10L,RNASEL,RPRD1A,TMLHE,ALG9,RORB,RPL15,UEVLD,BAALC,ATP8B4,GLDN,ACER3,ATAT1,KCNIP3,FOXRED2,SCP2,ASIC4,CASC3,SH3BP2,FHOD3,ST6GAL1,SYBU,ZNF365,SLC1A3,FAM81A,SLC1A7,SLC8A2,CCDC88A,SLC11A1,SLC12A4,ATF7IP,ARFGAP1,SLN,ANKRD36,MBD5,SNRPN,WDTC1,BDP1,IZUMO4,KDM4C,PEG10,SPTAN1,IQSEC2,NPAS3,LHPP,LMO3,ATP10B,ITPRID2,SSPO,COBL,KAZN,MTCL1,FAM208A,PDLIM2,TBCEL,ANO4,DMXL2,TCF7,TPCN2,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TNS2,HIF3A,GPR161,MTMR14,RIMBP2,CSMD1,C9orf85,ZNF384,NR2C2,PRMT8,DCBLD1,LRTM2,CLHC1,HIRA,UCHL1,PLEKHH2,CLIP2,NSD2,LGI4,MKRN3,LYPD6,AMZ1,ZNF213,SMARCAD1,PRDM2,RGMA,LINC02210,STOX2,ADAMTS9,VPS35L,PCDH15,GAL3ST3,NAV3,URM1,PPP1R3F,SLC17A6,CASC15,CAMK1G,ACTR3B,GAN,LAS1L,JPH3" MicroRNA hsa-miR-499-3p:mirSVR_highEffct hsa-miR-499-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-135 5.90E-132 1.54E-134 1.42E-133 323 1252 "KCNH8,NBAT1,XKR4,SLITRK1,TMCC3,BRAP,LRFN2,KIDINS220,SLC24A4,ZNF608,INTS2,MTUS1,AK2,SEMA6A,MAP4K3,CACHD1,PPP4R4,MADD,TMEFF1,ARRB1,PLA2G4C,CAPRIN2,ASPH,NCOA1,NUMB,SLC4A4,ATP2B1,NOL4,BARD1,NRP2,CDK5R1,FUBP1,IL33,CACNA1B,CACNB2,KALRN,PTBP2,SYT6,CCKBR,SEPT7,CDC42,CDH10,LRRFIP1,LGI1,MAGI1,CDO1,SRSF11,FOXN3,SYNPR,B4GALT6,TMEM155,FHL5,ARHGEF6,FAM149A,AKAP6,SLC4A7,RCHY1,RTTN,CNRIP1,SLC35F1,CPS1,SEC31B,C2CD2,GDA,SNCAIP,CSNK1G3,ATRNL1,SOCS5,PDE4DIP,CTH,RIMS2,USP6NL,EDRF1,GPRASP1,GAPVD1,ARHGAP24,KCTD8,DAPK1,ARMCX2,SPATA2,DNAJC6,ZNF804A,ZEB2,GSDME,POM121,SV2B,NTM,RABGAP1L,CPEB2,CASP8AP2,DPP6,SLC25A18,E2F6,EDN1,FRY,PHF20L1,SUGP2,MBNL2,EGR3,ASB3,ELAVL2,EPHB1,IGSF6,EFS,CDKL3,EYA1,ABCA8,WAC,ZIC4,TAOK3,SCML2,DLC1,SPSB4,FGF13,FGF14,ACTL6B,MAD2L2,AMOTL2,PRKAG2,FHL1,SUCO,UBE2E3,MEX3B,FOXG1,SEC23B,COQ5,UFM1,FAM49B,ERGIC3,CELF1,DACH2,STAU2,ABLIM2,ZMAT1,GABRB3,GAD2,GALC,ARPP21,NCKAP1,GAP43,MTHFD2,DISC1,GATM,SULT1C4,GLS,KDM2B,GPD2,EML4,GRIK1,GRM1,GRM3,PRDM5,GRM8,ZBTB49,MFSD2A,LINC01551,RASSF8,ARHGAP36,ELOVL5,HMGCL,HNF4G,HNRNPK,NEGR1,HSPA1L,FAAP20,ZNF181,IL6ST,ZNF678,JAK2,METTL21A,KCNA6,KCNJ3,KCNMA1,STXBP5,LAMP2,SYTL4,FGFBP3,PIK3AP1,MARK1,MARK3,MAT2A,AQP11,LRP1B,KITLG,MID1,CD200,MRPL42,RTL5,NAP1L3,NEK1,NF1,NFE2L2,LRIT2,NPR2,NTRK3,OPA1,OPCML,CLDN11,PAK3,PCSK2,PDGFRA,GNG2,SSH1,NALCN,ZNF655,RETREG1,XRN1,PURG,MAPKAP1,SCHIP1,ING3,PACSIN1,PPM1B,MAPK9,GRAMD1C,PROX1,DCHS2,RELN,CNTLN,PLPPR1,BDNF-AS,PTHLH,TMEM260,PTPRD,C1orf109,TMEM255A,PLEKHB2,ZNF793,RAP1GDS1,ZNF493,MSANTD2,ZMAT4,FIGN,RFX2,RFX4,SLC25A36,RNASEL,EXD2,CARF,GSTCD,TMEM206,UEVLD,RPS6KA2,LRRK2,RYR3,ZNF331,SEMA6D,FNIP1,SOX6,MRAS,NLGN4Y,DOCK10,NTNG1,SHC4,HKDC1,ABLIM3,PPP4R3A,EPN2,RADIL,SLN,ZNF667,RIMS1,SNAP25,SNCA,TMCC1,SON,MYT1L,SOX5,BDP1,DOK5,SP4,EMC1,ZNF423,C11orf87,SEPT8,DIP2A,FAM168A,PRRC2C,VPS13A,SYN2,ADGRL3,ANO4,DMXL2,TCF7L2,TRIM2,SYNE1,PUM2,C18orf54,HHIP,ACTR6,PRRT1,TPM3,TPM4,RGMB,TRPC3,TRPS1,TSN,ANO5,TMEFF2,UBE3A,ZNF781,RICTOR,ZIC2,ZIC3,ZNF24,CELF4,ZBTB38,ZFAND5,SMARCAD1,EMSY,DNALI1,LRP8,STOX2,ADAMTS9,MPPE1,SLC17A6,FAM13C,KAT6A,SMIM8,JMJD1C,FXR1,NETO2,CBLN2" MicroRNA hsa-miR-613:mirSVR_lowEffct hsa-miR-613:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-135 6.61E-132 1.73E-134 1.59E-133 391 1822 "SYN3,CLK4,EMILIN3,CSMD3,FMNL2,KLHL32,TMEM132B,ADD1,SORCS1,ADORA3,OLMALINC,AP1B1,INTS2,GPR158,PCDH19,KCTD16,RTL9,OSBPL6,CC2D2A,ZNF578,SEMA6A,PCDH10,UNC79,FAM135A,AMPD3,AMPH,AMT,CDC42BPA,LRCH2,PPFIA2,CACHD1,VAT1L,SHTN1,LGR5,PPP4R4,PDXK,CASK,TMEFF1,ARNTL,ARSF,CHRD,DYNLL1,EIF4G3,RNF182,NOL4,ATP6V0A1,TTLL9,ADGRB3,BCL2L2,MIR9-3HG,BCL7A,KSR1,SYNJ2,SCAPER,GYG2,SGCE,C5,OSGIN2,WASF1,MMD2,BTRC,CA12,CACNA1A,CACNB2,CALB1,PTBP2,SYT6,RUNX1T1,PRC1,METTL6,ENTPD6,SRSF11,CHM,CASC2,LSMEM2,NRXN1,TJP2,QKI,NIPBL,COL4A5,LETMD1,AKAP5,TBPL1,SMARCAL1,CLOCK,C2CD2,CRHBP,AKAP12,ANKRD44,CSF1R,ATRNL1,NCAN,CNTNAP2,SLITRK5,KIAA0040,PHF14,CTNND1,CTNND2,RIMS2,GPSM1,HDAC4,TOX,TBC1D5,AIF1L,C8orf34,ZEB2,PLEKHM1,MYEF2,KIAA0319,CEP170,MAGI2,SPOCK3,SRGAP3,FAM107B,KIF19,DLG4,HS3ST4,DMPK,USP3,CDON,GNE,DYRK1A,GOLT1B,EBF1,EDIL3,FAM135B,HEYL,KLHL5,TMTC1,SH3GLB1,ABI2,KCTD3,EIF4G2,EIF5,TENM1,PLEKHA1,RGS17,TMEM35A,EPB41L1,RCAN2,LRRC17,SRRM1,DENND4A,RRAGB,MRVI1,CLVS1,FAM198B,WAC,RPS6KC1,SH3YL1,PTK2B,ZIC4,TAOK3,FCGR1A,TESK2,ZNF589,FGF11,FGF14,BAIAP2,SUCO,SLC37A3,PDLIM5,TPK1,NPTN,KHDRBS3,NSG2,DLL3,TMEM151A,ZNF512,STAG2,GABRA1,GALNT15,ZMYND11,ZNF274,DISC1,CPLX2,MYOZ2,IGSF5,MSTN,GFRA1,MALT1,TOX3,KDM2B,GNAS,FUT10,LILRA1,GPR22,GRIA2,GRIA4,GRIK2,NR3C1,PRDM5,GRM7,GSTM5,IRAK3,RASSF8,UBE2QL1,KLF12,BACH2,ELOVL5,ACOT7,HNMT,OPALIN,LRRC75A,SMAP1,IRF8,IDH3A,FAM95B1,KNDC1,LRRCC1,IL6ST,BRINP3,ZNF678,INPP5B,ITPKB,KCNMA1,LIFR,PAXBP1,PACRG,SMAD1,ZNF667-AS1,MAP6,AQP11,SYT9,MOBP,MOG,GIT1,N6AMT1,ZNF92,NEXMIF,ZNF862,NCAM1,NCAM2,NDUFA5,ALDH1L2,VWA2,NTRK2,OPCML,ZNF827,ZDHHC22,GLIPR1L2,PAX6,PBX1,PRTG,GPR85,FAM218A,GPSM2,PMP22,RETREG2,EPB41L4B,TNPO2,PPP2R2B,BCAS3,WBP1L,SIDT1,GON4L,WDR25,CNTLN,PTPRN,ZNF793,FAT4,SUSD4,ZDHHC14,ZYG11B,REV3L,RGS3,RIC8B,ZFHX4,RERGL,CYB561D1,RORB,TMEM100,NEK11,ZNF671,TCP11L1,STK32B,ABCA11P,CCDC112,FAM192A,DGLUCY,DRAXIN,ATXN2,SCN3A,LINC00461,GALNT10,SFPQ,SUPT20H,SGK1,PPP1R9A,KIF16B,DOCK10,NTNG1,CHD9,FBXO11,SYBU,NUBPL,PPP4R3A,LRRC55,SLC6A8,SLC8A2,SLC8A3,SLC9A5,SHANK2,SLC12A2,TMEM132D,ATF7IP,ZFP1,SMARCA4,SMARCC2,MYH15,LIMCH1,MAPKBP1,TMCC1,DOP1A,TNIK,BDP1,SOX10,FNBP1,CLUAP1,ENKUR,CDK19,NFASC,SRPK2,EPB41L3,NCDN,MPRIP,ELOVL4,CEP68,SEPT3,FAM168A,SUPT5H,SYNE2,VAMP1,C3orf70,SYN1,C12orf76,TAL1,UNC5D,AGTPBP1,DOCK9,PHF24,PCDHB10,PCDHB9,PUM2,CCDC173,ZFPM2,CRB1,AP4E1,TGFBR3,TK2,ACTR6,DDHD1,TMOD1,BEX4,RIMBP2,CSMD1,KAT6B,TNR,PIK3R5,RUNDC3B,STXBP4,ANKRD20A2,TTTY15,HEPACAM,CADM1,RPRM,VLDLR,VSNL1,WIPF1,RICTOR,ZIC1,ZNF711,ZNF24,MKRN3,ZBTB38,ANKS1B,PLPPR5,UPF3A,PRDM2,LRP8,STOX2,PCDH15,FIP1L1,WIPF2,ST7,KAT6A,HNRNPA3,NETO1,LAS1L,FAM198A,SENP7" MicroRNA hsa-miR-4284:mirSVR_lowEffct hsa-miR-4284:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-135 6.83E-132 1.78E-134 1.64E-133 393 1840 "TTYH1,SDE2,GPRIN1,XKR4,ADCY2,ESYT2,AP2A1,AP2A2,INTS2,ZNF578,TAOK1,ALAD,SMIM17,SRPX,MARCH4,PCDH10,AMPD2,DPP10,ANK3,FGD2,CCDC146,MYH7B,PKP4,APBA2,GPAM,CACHD1,BCAS1,USP37,LGR5,SLC7A14,CDK10,KIAA1614,SFMBT2,TMEFF1,ZSCAN18,DACT3,NCOA1,TMEM108,ATM,ATP2B1,ALDH7A1,ATP6V0A1,ADAM15,BBS2,NRP2,KSR1,BMP7,ARHGEF7,LINC00906,WASF1,CALB1,KALRN,PTBP2,CAMK2B,CAMK2D,CAMK2G,SLC25A14,ISPD,KRIT1,METTL6,AIFM1,REPS2,ZBED1,LRRFIP1,LOC730101,LARGE1,MAGI1,DIS3L,SRSF11,PLEKHB1,CASC2,MS4A7,CHRNB2,NDST3,CLCN3,CLTA,CLTC,NIPBL,SUMF2,ABI3BP,SMARCAL1,CHD1L,SEC31B,ENTPD4,RBM39,GDA,AATK,SEC24C,SUSD5,SOCS5,KIAA0040,CTH,DCAF4,RUBCN,ECE2,FGFR1OP2,GAPVD1,TCAF1,RIPOR2,CENPL,MFAP3L,HP1BP3,KLHL3,DDX46,GUCD1,PLPPR4,SPOCK3,SV2A,ARNT2,RAB39B,DNM1,RPS6KL1,MED12,CDON,DOCK2,PDCD6IP,GNE,MAMLD1,KRBA2,EBF1,EDNRA,SEMA3D,KLHL5,OPTN,PHF20L1,LPAR6,EIF5,IRAK4,COPS4,ELAVL2,MRNIP,C8orf37,VPS13B,COQ7,KCNMB2,RABEPK,SLC43A2,NCALD,ETV1,VPS26C,ANKMY1,TBC1D16,SCML2,RACK1,TOMM40L,POLR1B,FGF11,POLK,IP6K2,PCYOX1,SEMA6C,FOXO3,FLT1,SLC37A3,EFCAB2,TRIM16,PNMA2,TVP23A,ZNF44,GABRB1,GABRB3,FAM184B,DENND2A,GALC,TMEM8B,SEPT9,INPP5K,KIAA1841,SRCAP,SESN1,GFAP,GFER,NTNG2,BRD8,GK,ZNF276,TXNL4A,CRCP,TCERG1,DBF4,RAB30,GLS,TNRC6A,PCDH11X,KDM2B,LUZP2,GNG3,GOLGB1,CCDC184,NUDT21,EML4,PLCD4,SPACA9,ADAMTS13,GRM7,GRM8,AP4S1,RASSF8,PADI2,MAN1B1,BACH2,HSF2,HTR2A,ATCAY,MYLK2,ZNF546,USP54,SCIN,LIX1,KCNJ5,GATD1,LIMS1,SYTL4,NCOA7,MARK1,SYT9,MEIS1,AFDN,MOG,MT1M,RSPO2,MXI1,LYRM9,MYO6,HNRNPM,NAP1L1,NEFM,NEUROD1,VWA2,SLC11A2,SMIM11A,NUCB2,OGDH,CLDN11,P2RX7,PALM,PDE1A,PDGFRA,GNG2,PFKFB3,OLA1,ZDHHC8,SSH1,FTO,ANKRD16,LRP12,MBOAT7,PILRA,TNPO2,POU3F2,CRLS1,PPP3CB,NKAIN4,PRKACB,PRPH,SYTL2,PTHLH,PTPRB,OCIAD1,C1orf109,CCDC40,PLEKHB2,ZNF793,NWD1,ZNF493,ZMAT4,RFX4,RGS12,PRIMA1,PBRM1,ARMC5,CARF,GSTCD,ROBO1,ROBO2,CCDC25,TMEM206,CCDC102B,RPL15,GLDN,PRR5L,ADAL,ACER3,ZNF331,DGLUCY,HOGA1,SCN3A,ELMOD1,GALNT10,ASRGL1,MRAS,FBXO11,ABLIM3,PEX26,KANSL3,SLC6A8,RAB3GAP1,CCDC88A,SLC11A1,SLC12A2,INTS9,INAVA,RIMS1,SNCA,SNRPN,PALLD,FAM126B,UNC80,KDM4B,USP33,PDZD2,SOX1,SP2,MYCBP2,KDM4C,TEX2,UNC5B,SPTAN1,LMO3,POGZ,COLGALT2,ZSCAN29,NEK4,STAC2,SEPT3,JMJD6,ADAMTS17,ANKRD28,KAZN,CAMTA1,EXOC7,TAL1,MGRN1,VWA3A,EHBP1,ACSL6,SYNE1,TNS2,RNF216P1,FAM200B,DICER1-AS1,CRB1,AP4E1,ZNF106,HHIP,SLC44A1,GZF1,NR2E1,ERCC6L2,KAT6B,TP53BP1,CDK20,TPM3,C9orf85,TPM4,ZNF346,ELP5,NEIL2,PLEKHH2,BCL2L13,TBC1D15,P2RY12,LAT2,RICTOR,PCDH20,ZNF708,ZNF74,GPR158-AS1,ZBTB16,TMEM237,EML6,DPYSL5,PCBP1-AS1,SLC30A3,SLC30A4,ZXDA,EMSY,LINC02210,RNF103,HPS4,SIGLEC10,SNX27,FIP1L1,LINC00632,CAB39L,MPPE1,MVB12B,PAK5,KAT6A,FBXO36,JMJD1C,TIGD6,JPH3" MicroRNA hsa-miR-1253:mirSVR_highEffct hsa-miR-1253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-135 1.01E-131 2.63E-134 2.42E-133 371 1649 "KCNH8,ACLY,DSCAML1,ADD2,PTCHD1,NLGN4X,SLC24A4,RTL9,TAOK1,C1QTNF3,LRRC7,SMIM17,SPOP,FAM135A,AMPD2,LRFN1,DPP10,ANK2,SEMA7A,LCORL,SUGT1P4-STRA6LP-CCDC180,ALS2,FAM131A,MIER1,MADD,CADPS,DNAH17,DACT3,ATP1B3,STX16,ATP2B1,DPY19L3,ATP6V1G2,DOCK11,LINC00847,NRP2,DST,SYNJ1,BTK,CDK5R2,CA4,CA8,KALRN,HAP1,CAMK2D,VSTM2A,ISPD,LDB2,MTMR7,INA,CD86,DGKI,ZBED1,CDH18,TIGD7,SRSF11,CHN1,SYNPR,TAOK2,KMT2C,RAB33A,CLCN4,TPP1,QKI,NIPBL,BTF3L4,SLC4A7,SLC4A8,ABI3BP,MYRIP,MFSD4A,SLC35F1,CPS1,HAPLN1,RNF14,ANKRD44,MICAL2,NCAN,NRSN1,ZSCAN23,USP6NL,CCDC144A,CYBB,FGFR1OP2,ARHGAP24,DCAF8,FRMPD4,ZFYVE16,DGKB,DAPK1,ELMSAN1,DNAJC6,MFAP3L,CEP170,LYPD1,AK5,DLG2,DLG4,GRIN3A,RAB39B,HS3ST4,DTNB,ECM2,ABCC5,AASDH,EBF1,FAM135B,RASGRP1,FSD1L,SIDT2,YAF2,SUGP2,KMT5B,ING4,EPHB1,KCNMB2,EPS8,CEP85L,CDKL3,RRAGB,FAM198B,AMZ2,RPS6KC1,ZIC4,TAOK3,DLC1,CEP78,ZSCAN30,POLR1B,FGF14,POLK,UBE2E3,CAP2,FLNC,JKAMP,UFM1,DACH2,DLL3,STAU2,TBR1,FYB1,MEGF10,GABBR1,HRASLS5,CAB39,AHCYL1,GAP43,ERAP1,NEU3,GFRA2,TCERG1,MSL3,ZNF638,KDM2B,TDRKH,STON1,EML4,PCLO,RAPGEF4,ATP2B1-AS1,GRIA4,GRIN2C,ATE1,GRM7,TMEM25,MFSD2A,MAEL,ZHX1,NXPH2,MAN1B1,ATXN2L,HNF4G,HSF2,SMAP1,NKD1,KIAA1755,PLD5,IGSF1,IL6ST,ITGAM,KCND1,KCNMA1,KHK,KIF5A,KIF5C,STXBP5,HECTD2,FGFBP3,ARHGAP12,PACRG,MAN2A2,MAP4,MAP6,MARK1,MBD1,TM6SF1,MEIS1,KITLG,ERICH3,COL28A1,MT1M,N6AMT1,MTR,LYRM9,PABPC1L2A,FXYD6,NBL1,NCF2,CCDC13,NF1,HCN1,IGSF11,OLR1,PAK3,PCDH9,PCSK1,PDE1C,PDE4B,GPR173,ABCB1,ANLN,XRN1,PLP1,HMGCLL1,PMP22,SCHIP1,ING3,POLG,POLR2F,DRAM2,MED1,PRKACB,CEP41,PKN2,HYDIN,DIRAS2,SAMD9,SIDT1,GDPD2,CNTLN,PLPPR1,TMEM260,PEX5,ZSCAN2,NKAIN1,NWD1,DBX2,MSANTD2,RDX,MORC4,RFX4,RFX5,UBR7,RGS4,SEC61A2,RNF220,PBRM1,RPRD1A,DCUN1D2,TMLHE,CARF,CYB561D1,ROBO2,RPL15,FBXW7,ATP8B4,TCP11L1,LRRK2,HSD11B1L,ATAT1,WLS,RTN1,CSRNP3,ATXN7,SCN8A,PRCD,TNFRSF19,ZFP30,PPM1E,SHMT2,R3HDM2,NLGN1,SLA,SLC1A7,WDR47,LRRC55,CCDC88A,SLC9A5,SLC12A2,EFHD1,ATF7IP,TET1,INTS9,ANKRD36,FAM126B,SCN3B,DOP1A,WDTC1,KDM4C,UNC5B,SPTAN1,TAB2,ATP10B,PBLD,CLASP2,ERBIN,TTBK2,DIP2A,SYT11,VPS13A,COBL,FAM208A,ADGRL3,ANO4,ACSL6,TCF4,TPCN2,WASHC4,SYNE1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEK,AP4E1,HHIP,MTMR14,TK2,DDHD1,BHLHB9,LRRC8A,TPM2,TPM4,ZNF346,METTL3,STXBP4,FNDC5,DCBLD1,TSC1,HSPBP1,TMEFF2,CADM1,LAT2,SLC13A3,ZBTB14,KCNT2,ELFN1,NDRG4,TCEAL7,ZNF142,REEP1,FSTL5,PLPPR5,SYNC,MAP3K12,STOX2,TMEM178A,HPS4,VPS35L,FAM47E,C12orf4,FAM13C,KAT6A,NLRP3,NHSL1,AP3B2" MicroRNA hsa-miR-3162:mirSVR_lowEffct hsa-miR-3162:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-135 1.32E-131 3.41E-134 3.14E-133 359 1548 "CPNE2,KCNH8,ACADM,ASIC1,NCKAP5,ADAR,ADARB2,GALNT16,GALNT13,ADD2,SLC12A5,ADORA2A,KIAA1211,RNF150,PTCHD1,CASKIN1,TBC1D14,ADGRF5,MARCH4,FAM135A,KIF6,LRFN1,CDC42BPA,LRCH2,LCORL,PHF12,APLP1,PHYHD1,BCAS1,SHROOM2,SEMA4G,PRX,ATM,ATP1A2,SLC4A4,ZNF583,SLC2A11,RNF182,ADAM23,MPDZ,DNAJC27-AS1,CFLAR,LINC00906,SCAPER,CFAP410,CALB1,TRIM41,VSTM2A,ISPD,RUNX1T1,USP2,INA,SEPT7,KCNAB3,CDH8,CDH10,CACNA2D2,ASIC3,PLEKHB1,CASC2,RAB3C,LHX2,EPS15L1,CNN3,BTF3L4,IFFO1,ZNF385A,CREM,CRYBB1,GDA,CSF1,CSF1R,MICAL2,OSBPL3,VCAN,SOCS5,PDE4DIP,FAM169A,PLCXD3,CTNND2,NOS1AP,CYBB,BOC,PHF19,ZFYVE16,TM9SF4,PHYHIP,DGKG,ARMCX4,DCC,PITPNC1,ZNF804A,C8orf34,ZEB2,ELMO1,CEP170,MAGI2,KLHL3,SNAP91,CHRDL1,DLG2,DLG3,CDON,DPP6,ACOT8,GNE,DNAJB6,DYRK1A,FARSB,E2F5,EDNRB,SUGP2,APH1A,IRAK4,CERCAM,ELN,EPB41,COQ7,DMTN,EPHA5,VPS26C,SIRPB1,CD320,F5,CLVS1,ABCA8,PTK2B,DLC1,CHST15,TOMM40L,FDFT1,ZNF589,FGF11,BAIAP2,POLK,FLT1,SGIP1,SORBS1,AK8,STAMBP,ARFGAP2,ZNF512,NEURL4,ZMAT1,GAA,GALNT15,GABRB3,GABRG2,NCKAP1,INPP5K,GCK,GLS,MSL3,GNG4,CNDP1,ATF7,STON1,RAPGEF4,GRIA1,DIDO1,PRDM5,RNF165,BVES,GUCY1A2,RNFT2,GUCY1B1,IRAK3,TOX2,ZHX1,NXPH2,SYNPO,ZNF491,SMAP1,ZNF181,ZNF678,SLC35G1,KCNA6,KCNB1,KCNJ5,KCNK1,KCNK2,KIF5C,TTYH2,LAMP2,INSYN2,VWA5A,LOC100128239,ZFYVE27,MARK3,MBP,ADAM11,KCTD6,SCAMP5,ERICH3,ZNF680,JAKMIP3,MYO9A,NAP1L1,NDUFA5,NELL2,ALDH1L2,NINJ2,NOS1,DDR2,NUCB2,NUMA1,OCRL,OPCML,PAK3,PCSK2,PDCD2,PDPK1,GNG2,ZDHHC8,PIK3C2A,FAM216A,SLC25A23,PURG,SPATA6,TNPO2,SH3KBP1,PPP2R2B,CRLS1,PTPA,PPP3CC,PRKACB,RAB39A,MAPK4,HYDIN,RELN,BDNF-AS,TMEM260,ZSCAN32,OCIAD1,PTPRE,CASTOR1,FAM120C,TUG1,QDPR,RAB5B,CEP97,ZNF493,DBX2,ZDHHC14,GAL3ST4,ZYG11B,ERI2,TTLL7,SEC61A2,CARF,KIRREL1,NEK11,SPIN3,PRR5L,STK32B,LRRK2,ST6GALNAC6,KCNIP1,ZNF568,RYR3,AP1AR,SARS,ATXN7,SCN8A,ELMOD1,PEAR1,SEC14L1,TRIM46,CASC3,ITSN1,FAM102A,KIF16B,FBXO11,FAM214B,LRRC55,SLC8A3,ARHGEF40,CCDC88A,SMARCE1,SNRPN,SCN3B,MYT1L,KIF21B,SOX10,ZSWIM8,SP4,NMNAT2,BEX1,TSPYL2,NPAS3,RAP1GAP2,NFASC,ITPRID2,STOX1,ZSCAN29,SEPT3,NECAB1,MLC1,RHBDL3,ARHGEF9,SYT4,TAC1,FAM208A,TBCEL,IQCE,ZFP90,TCF7,RPGRIP1L,USP22,CLASP1,SYNE1,PHF24,SLC19A3,TEK,SIRT1,TGFBR3,HHIP,FBXL16,TJP1,RIMBP2,R3HDM1,RASD2,NPL,WBP2,ZNF384,ZNF346,SYNPO2,PRMT8,SSBP2,TTTY15,LRTM2,HIRA,HEPACAM,FAM155A,LMF1,WIPF1,GUSBP1,EML6,SH3GLB2,MEIS3,EVI5,STOX2,RNF103,GAL3ST3,NAV2,PCBP4,PDSS2,RGS7BP,GJC2,CASC15,CERS6,RNF170,VANGL2,SLC39A12,PIANP,NETO1,RNF146,SLC4A10,FAM198A" MicroRNA hsa-miR-3118:mirSVR_lowEffct hsa-miR-3118:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.61E-135 1.46E-131 3.78E-134 3.48E-133 368 1625 "SDE2,ASIC2,ASIC1,ABHD6,KLHL32,RNF157,ADD1,ADORA2A,KIAA1211,KIDINS220,OLMALINC,MTA3,ZNF608,NR0B1,TXNDC16,ZNF578,LRRC7,ALCAM,PCDH10,BBOX1,KCNT1,AMPD2,DPP10,MAP4K3,MYH7B,CNIH2,KCNAB2,DGKZ,GPAM,AMER3,BCAS1,SHROOM2,CASK,LINC00173,ATM,SLC4A4,STX16,TTLL9,ADAM15,SEC11C,RGS11,LINC00906,BTK,SCAPER,NIPA1,CFAP410,CACNB4,CALM1,SPAG9,INA,TMEM257,ENTPD6,SEPT7,CDH2,CDH8,LRRFIP1,DLGAP1,FOXN3,B4GALT6,KIAA1549L,CLTA,FBXO7,ABCG2,SRP14-AS1,CNR1,AKAP6,COL4A5,SLC4A8,COX4I1,CHD1L,NECTIN3,ZNF385A,CSF1R,CSF3R,CSNK1E,CSNK1G3,ATRNL1,VCAN,NCAN,SOCS5,FAM169A,PPP1R16B,SDC3,ARHGEF4,GPSM1,RUBCN,KIAA0408,ARHGAP32,FRMPD4,INTS1,SCRN1,DNAJC6,ZEB2,ELMO1,TIAM2,MFAP3L,MAGI2,BLOC1S6,CHRDL1,DLG2,DLX1,GRIN3A,DNM1,SLC29A4,CDON,CPEB2,DTNA,DYRK1A,ABCC5,KRBA2,EDN3,ANKRD46,RASGRP1,PHF20L1,EGR3,PLEKHA1,ELAVL3,PAN3,ZNF549,MRPL10,FAM198B,CEP78,ZNF589,FGF1,FOXM1,FLT1,SLC37A3,NELFCD,NBEA,TMEM107,HVCN1,UFM1,CAMKK2,CELF1,STAU2,KBTBD12,AP4B1,OGA,DKK3,MEGF10,ZNF559,SRRM4,GATM,GCNT2,NFU1,TTBK1,RNPS1,HPGDS,ZNF782,GNG4,GPD1,GPD2,FUT10,GPER1,NUDT21,ATP2B1-AS1,GRIA1,GRIA2,GRM1,FAM19A2,KAT7,MAEL,RASSF8,PADI2,GPR45,BACH2,ACOT7,HPSE2,GABARAPL2,HMGCL,NEGR1,IDH3A,C5orf24,KNDC1,TJAP1,PLD5,HES5,IL6ST,BRINP3,DIPK1A,KCNA4,KCNA6,KCNC2,CREG2,KIF5C,INSYN2,LIMS1,PAXBP1,ARHGAP12,CHIC1,MEIS2,MGAT3,PPM1L,MKLN1,MOG,RSPO2,MYCN,MYO6,PABPC1L2A,NCAM1,ZC3H12B,NDUFA5,NEUROD1,NF1,NPR2,NUCB2,TBC1D25,OCRL,OPCML,KCNK10,PAK3,DPY19L2P2,PCSK1,PCSK2,PDE4B,PDE4D,PDPK1,ANLN,GPSM2,PLCL1,FTO,SLC25A23,PRIMPOL,PMP2,SCHIP1,ING3,RANBP3L,VPS13C,SYTL2,MTMR10,TMEM260,NKAIN1,TUG1,MARCH1,PID1,CEP97,SLC25A48,CCDC40,FAM66C,NWD1,ENOX1,RASGRF1,RDX,ZMAT4,REV3L,GTDC1,RFX2,UBR7,RGS4,RGS7,ALG9,ROBO1,KIRREL1,EPHA10,ARMH4,FBXW7,SPIN3,ZC3H14,ZNF671,GLDN,ACER3,MAP6D1,RXRG,NCBP3,ZNF331,AMER2,FOXRED2,HOGA1,LRRTM4,FNIP1,CASC3,MRAS,SUPT20H,PPM1E,CPEB3,WDR37,CCDC88A,SLC12A4,SLIT1,CPEB4,MAST1,MYH15,FAIM2,PALLD,FAM126B,DOP1A,PDZD2,WDTC1,SOX5,FNBP1,DOK5,ENKUR,UHRF1BP1L,KDM4C,LHPP,ATP10B,TROVE2,STOX1,SSTR1,NKAIN2,ZSCAN29,FAM168A,SYT11,ARHGEF9,C3orf70,SYN2,COBL,MTCL1,PJA1,CAMTA1,ADGRL3,VWA3A,SIN3B,RPGRIP1L,SZT2,WDR7,SYNE1,PHF24,PCDHB7,PUM2,TNS2,FRYL,CCDC173,PMS2CL,AP4E1,ZNF106,MTMR14,TMOD1,FAM124A,ELP5,TRIO,TRO,STXBP4,TRPS1,DCBLD1,TMPRSS5,ANO5,TTTY15,UBTF,GORASP1,PLEKHH2,CCDC136,VLDLR,TBC1D15,KLC2,CLDND1,KCNK12,ZNF45,LYPD6,TMEM237,POLR3H,EML6,SMARCAD1,UPF3A,ZXDA,CADM2,SLC38A1,RNF103,FIP1L1,EPM2A,DOCK8,ST7,HNRNPA3,JMJD1C,RNF170,SNX14,FAM181A,GAN" MicroRNA hsa-miR-1260b:mirSVR_lowEffct hsa-miR-1260b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.84E-135 1.59E-131 4.11E-134 3.78E-133 387 1791 "SDE2,ASPHD1,ASIC2,ABHD6,TMEM132B,GALNT16,GALNT13,AXIN2,SLC12A5,PNMA8B,ADORA3,LRFN2,CC2D2A,TAOK1,UNC79,FAM135A,SYT13,PDZD4,OGT,SEMA7A,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,GPAM,PHYHD1,VAT1L,TNRC6C,APP,AQP6,SEMA4G,SPTBN4,ARRB2,DNAH17,MARK4,ASPH,TMEM108,ATP2B1,ATP2B2,ZNF583,BBS2,DCAF5,BTK,C1QC,CACNA1I,CACNA1G,CDK5R2,CA4,CACNB2,CACNB4,KALRN,NGB,ARHGEF25,CBLN1,KRIT1,P2RX6,CDC25B,DCLK1,LRRFIP1,LGI1,L3MBTL4,UBE2L6,CHRM1,TAOK2,ARHGAP22,LHX2,IGFBP7-AS1,ZFYVE9,ARHGEF6,COL4A5,SUMF2,IFFO1,MFSD4A,ZNF385A,ANKRD44,NCOR2,ABCG1,RGS6,LRIG1,ARHGEF10,MICAL2,OSBPL3,PLCH2,VAC14-AS1,CST3,PLXNA4,SLITRK5,GREB1,RIMS2,RUBCN,ECE2,CYBB,RIPOR2,ARHGAP24,DCAF8,KIAA0513,RASSF2,LIN54,TOMM20,SPOCK2,AIF1L,GIT2,ARMCX4,ZEB2,ELMO1,CNIH3,C2CD2L,GUCD1,SRGAP3,RABGAP1L,TMCC2,ARNT2,ZNF582-AS1,DLG2,HS3ST4,USP3,NR1D2,CDON,DTNA,DTNB,TOM1,DYRK1A,ABCC9,EDNRA,YAF2,EFNB3,CELSR3,GPR61,KMT5B,COQ7,LRRC17,RASGRP2,MTSS1L,EPHB1,SPEG,ETV1,SIRPB1,ECSIT,EZH1,NRN1,CACNG2,CORO2B,FCGR1A,TOMM40L,PPP1R1B,SLC9B2,POLR1B,FGF14,FHL1,CAP2,FOXM1,FLT1,CAMKK2,ATP2C1,ERGIC3,KBTBD12,SARAF,ABLIM2,TVP23A,STAG2,MEGF11,GABBR1,GABRA3,GAD1,ZMYND11,JPH4,RAPGEF6,SIGLEC8,ALDH1L1,USP19,GGT7,NTNG2,GLUL,DCLK2,LILRB4,TMEM121B,RAPGEF4,GRIA1,GRIA2,PLPP7,ADAMTS13,RNF165,PTPN5,BVES,PSIP1,TMEM179,PADI2,NCKAP1L,ARHGAP36,VSIG4,ELOVL5,AGBL5,HNF4G,HNRNPK,USP51,HSF2,CELF5,SMAP1,IRF8,MSL1,MYLK2,SCRT2,IL11RA,LRRTM3,ITGAM,SLC35G1,KCND1,KCNJ11,KCNMA1,LAMP2,LIMS1,MAT2A,MDM4,MEF2C,MEIS1,MIA2,MMP16,MOBP,ZNF92,MYO7A,NDP,CCDC13,NEK1,NINJ2,NOS1,SLC11A2,NTRK2,NUMA1,TBC1D25,SNTG1,PDE1A,PDE2A,ABCB1,GDAP1L1,SSH1,CAMKV,ZFYVE21,GPSM2,STRN3,RC3H2,PSAT1,SCHIP1,ING3,SEPT4,PACSIN1,TNPO2,FSD1,PPP1R1A,PTPA,MAPK8,MASP1,SLC22A23,CYBC1,APTX,MDGA2,TMEM104,PIGG,CNTLN,UHRF1BP1,MTMR10,ZIK1,PTPRG,FAM120C,PEX5,ZNF615,PID1,CCDC40,PLEKHB2,FAM66C,ATG16L1,RAP1GAP,FIGN,RFX3,RFX4,RGS4,SUGCT,EXD2,ARMC5,GSTCD,CYB561D1,TMEM100,EPHA10,RPL15,GLDN,LGR4,SOX8,HSD11B1L,KCNIP3,RTN1,TMEM156,LINC00461,PRCD,ASIC4,ZFP2,SOX6,TRIM46,ASRGL1,SGK1,PPM1E,CHD9,ST3GAL3,ANKRD6,SLC1A6,BTBD3,RUFY2,SLC6A8,SLC6A9,SLC14A1,CDK5RAP2,ANKRD36,LIMCH1,SNCA,FAM219A,NMNAT2,CLUAP1,EMC1,KDM4C,IDI2-AS1,PEG10,ATP10B,POGZ,SMOC1,ZC4H2,LRRC4,CEP68,VAMP1,NUDT10,SYN2,SYPL1,TACC1,EXOC7,TAL1,KIAA0930,CLASP1,TMEM151B,SLC19A3,TNS2,CYB561A3,AP4E1,ZNF106,BHLHB9,DAAM2,C5orf64,TP53BP1,ZNF346,METTL3,PRMT8,TRH,NUTM2A,DCBLD1,RUSC1,SSBP2,TUB,ZKSCAN5,UBTF,GORASP1,WIPF1,LAT2,LGI4,ZBTB14,ZIC3,ZNF708,ZNF74,SLC26A10,PCBP1-AS1,SPIRE1,WNK1,EMSY,PRDM2,STMN4,VPS35L,PPP1R3F,WIPF2,SLC17A6,PAK5,TMEM63C,CASC15,NUP214,FAM219B,JMJD1C,ZNF248,TIGD6,FXR1,IFT88,PRRT4,FAM198A" MicroRNA hsa-miR-518f*:mirSVR_lowEffct hsa-miR-518f*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-135 2.08E-131 5.31E-134 4.90E-133 363 1584 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,ARHGAP20,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,TNRC6C,SHTN1,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,SRP14-AS1,ARHGEF6,SLC4A7,SLC4A8,AHCTF1,ACBD5,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,NOS1AP,HDAC9,PHYHIP,SPOCK2,DNAL1,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,RABGAP1L,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,ATP8A2,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,PDGFRA,NALCN,A2ML1,SNX10,PLIN1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,MAPK10,GRAMD1C,HYDIN,PROX1,QRICH1,CNTLN,PTHLH,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,TTLL7,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,NTNG1,FBXO11,ST3GAL3,CTXN2,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SLC8A3,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,TJP1,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC3,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-518d-5p:mirSVR_lowEffct hsa-miR-518d-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-135 2.08E-131 5.31E-134 4.90E-133 363 1584 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,ARHGAP20,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,TNRC6C,SHTN1,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,SRP14-AS1,ARHGEF6,SLC4A7,SLC4A8,AHCTF1,ACBD5,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,NOS1AP,HDAC9,PHYHIP,SPOCK2,DNAL1,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,RABGAP1L,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,ATP8A2,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,PDGFRA,NALCN,A2ML1,SNX10,PLIN1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,MAPK10,GRAMD1C,HYDIN,PROX1,QRICH1,CNTLN,PTHLH,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,TTLL7,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,NTNG1,FBXO11,ST3GAL3,CTXN2,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SLC8A3,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,TJP1,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC3,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-526a:mirSVR_lowEffct hsa-miR-526a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-135 2.08E-131 5.31E-134 4.90E-133 363 1584 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,ARHGAP20,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,TNRC6C,SHTN1,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,SRP14-AS1,ARHGEF6,SLC4A7,SLC4A8,AHCTF1,ACBD5,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,NOS1AP,HDAC9,PHYHIP,SPOCK2,DNAL1,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,RABGAP1L,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,ATP8A2,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,PDGFRA,NALCN,A2ML1,SNX10,PLIN1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,MAPK10,GRAMD1C,HYDIN,PROX1,QRICH1,CNTLN,PTHLH,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,TTLL7,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,NTNG1,FBXO11,ST3GAL3,CTXN2,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SLC8A3,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,TJP1,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC3,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-520c-5p:mirSVR_lowEffct hsa-miR-520c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-135 2.08E-131 5.31E-134 4.90E-133 363 1584 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,GALNT13,ADD1,ADORA2A,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,ARHGAP20,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,TNRC6C,SHTN1,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,ZBTB10,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,SRP14-AS1,ARHGEF6,SLC4A7,SLC4A8,AHCTF1,ACBD5,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,NOS1AP,HDAC9,PHYHIP,SPOCK2,DNAL1,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,RABGAP1L,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,MED12L,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,ATP8A2,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PCSK5,PRTG,PDGFRA,NALCN,A2ML1,SNX10,PLIN1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,MAPK10,GRAMD1C,HYDIN,PROX1,QRICH1,CNTLN,PTHLH,PTPRN,STRC,SH3TC2,RASGRF1,ZMAT4,REV3L,RGS4,TTLL7,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,KIAA0895L,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,NTNG1,FBXO11,ST3GAL3,CTXN2,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SLC8A3,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,ITPRID2,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,RNF216P1,PMS2CL,SIRT1,ITGB3BP,AKTIP,MTMR14,TJP1,RIMBP2,TRIO,STXBP4,TRPS1,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC3,ZNF711,ZNF23,ZNF24,TRIM9,AGMO,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,CIAPIN1,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-1265:mirSVR_lowEffct hsa-miR-1265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.11E-135 2.31E-131 5.87E-134 5.41E-133 377 1705 "ASIC1,SYS1,ACTN1,KLHL32,SORCS1,GRAMD1B,PWWP2A,KIAA1211,ADORA3,RTL9,OSBPL1A,KIAA1324,AK2,C1QTNF3,LRRC7,ABCD2,ARHGAP20,ALK,KIF6,ZFAT,CCDC146,SUGT1P4-STRA6LP-CCDC180,EPB41L5,APLP1,UPRT,NT5C3B,AQP6,SFMBT2,SEMA4G,CDK13,MARCH3,ASPH,PCDHGB4,NCOA1,INSYN2B,ATP1B3,STX16,N4BP2L1,DPY19L3,TTLL9,ADGRB3,MPDZ,BMP7,DST,GPC2,BTRC,CA12,CACNB4,CALB1,KALRN,CAMK2D,TRIM41,HIP1R,USP6,LRBA,CDC27,CDC42,CDH8,EVI5L,LGI1,LOC730101,TIGD7,UBE2L6,SRSF11,CHGA,ASIC3,CASC2,CPNE6,RAB33A,CNTN1,ARMC8,ABI3BP,CLOCK,CREM,SNCAIP,CSNK1G3,CNTNAP2,CST3,SLITRK5,SEC14L5,DOCK4,HDAC9,FRMPD4,RASSF2,LIN54,DGKB,TMEM170A,SCRN1,AIF1L,SIRPA,SPATA2,YTHDC1,ELMSAN1,ZBTB24,MYEF2,ELMO1,TIAM2,ALKBH8,SRGAP3,WDR20,FAM107B,KBTBD11,CPEB2,SLC12A6,DTNA,ECM2,SYT15,FSD1L,PHF20L1,EGFR,MBNL2,KMT5B,ELAVL2,EIF1,EPB41L2,KCNMB2,ENPP6,ANKRD13B,RABEPK,DNAJC27,TLR7,KATNAL1,ADGRV1,CD320,F5,FAM198B,WAC,SCML2,FCGR1B,GORAB,AMOTL2,PRKAG2,CAMSAP1,FOXO3,EFCAB2,TMEM107,TPK1,ATP2C1,DLL3,STAU2,ADGRA1,TBR1,ABLIM2,MEGF11,HRASLS5,CHL1,GABRB1,GABRG2,AHCYL1,IQGAP2,INPP5K,WASF3,ALDH1L1,MSTN,ARFIP1,AHDC1,PPARGC1A,TCERG1,GLS,GNG4,LILRA1,GPR34,PCLO,GRIN2D,RNF165,BVES,ADAMTS6,GUCY1A1,GYG1,IRAK3,RASSF8,NXPH2,PACSIN2,ARHGAP19,MIER3,ZDHHC15,HSPA1L,LRRC75A,SMAP1,IBA57,SLC35G1,KCNC2,KCNK3,KCNMA1,KIF5A,INSYN2,SYTL4,SMAD1,NAT8L,MAP4,MARK1,SYT9,KITLG,MID1,PPM1L,POC1B,MOBP,ERICH3,ZNF680,DBNL,ADAM22,MSR1,NRBP2,CTNNA3,MTTP,MYO7A,ZC3H12B,NEK1,NELL2,NODAL,VWA2,SLC11A2,NTRK2,LOC100128398,OXTR,P2RX7,SNTG1,PAX6,PCDHGC3,PCSK5,PDE1C,PDE2A,GPR85,GNG2,CDK14,NLGN3,SEMA5B,TMIE,GPSM2,ST8SIA5,PLIN1,PLXNB1,PDZRN4,PMP2,STRN3,LRP12,EPB41L4B,NXPH1,POU6F1,PPARA,PPP3CA,PRKAB2,MAPK4,MAPK10,DIRAS2,CNNM2,BCAS3,WBP1L,SIDT1,PSMD13,CNTLN,ANKHD1,PTPRB,PEX5,STRC,SLC25A48,RALGDS,ZDHHC14,RET,RIC8B,LGI2,CCDC82,TMLHE,ROBO2,SNX22,NEK11,RPS6KA2,STK32B,CNTNAP3,NCBP3,DGLUCY,ATXN2,LRFN5,PRCD,SMPD3,TRIM46,COPZ1,DOCK10,SEC31A,ST8SIA1,SLC2A5,LRRC55,KDM4D,SLC8A1,SCMH1,TET1,CPEB4,SMARCE1,IFT122,ANKRD36,SNAP25,UNC80,FAM219A,SOX5,KIF21B,DOK5,KDM3A,SP2,ZSWIM8,ZNF423,DDN,SPART,NFASC,TAB2,CLASP2,CLSTN2,COLGALT2,LARP4,SEPT3,STXBP1,GSE1,ARHGEF9,VPS13A,PLCB1,CNTN2,AGTPBP1,KLHL4,WSCD1,SIN3B,TRIM2,RPGRIP1L,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,NSD1,GPRIN3,ATP13A2,CRB1,AP4E1,ARL10,TIAM1,TLR4,DAAM2,TNR,PIK3R5,SMUG1,NEIL2,STXBP4,PPIL6,SGK3,BEST1,VSNL1,LGI4,ZBTB14,ZNF23,ZNF24,TRIM9,SLC30A3,EMSY,SLC38A1,STMN4,FIP1L1,MPPE1,SLC17A6,GOPC,DOCK8,UBE3B,KAT6A,FBXO36,FAM219B,ZNF248,SNX14,NETO1,FAM198A,JPH3" MicroRNA hsa-miR-181c-5p:TargetScan hsa-miR-181c-5p TargetScan 5.59E-135 3.14E-131 7.91E-134 7.28E-133 285 974 "CPNE2,ASIC1,NDRG2,FMNL2,ADARB2,GALNT16,CCDC85A,BRAP,ERMN,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,ANK1,C6orf89,PPFIA1,GAS7,MADD,CAPRIN2,ASTN1,DDX3Y,ATM,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,HCN2,KSR1,JAZF1,FOXK1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,CDC27,CDH8,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,RAB3C,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,MAP4K4,NIPBL,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,CTNND1,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,CTIF,DNAL1,ELMSAN1,MFAP3L,KLHL3,BLOC1S6,G3BP2,MTX3,ARNT2,DLG2,NR1D2,CDON,DPP6,DPYSL2,DRD1,ABI1,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELAVL2,ELAVL4,ELN,EML1,PAN3,EMX2,EN2,EPB41,DMTN,NCALD,CLVS1,SCML2,ATP8A1,MED12L,FGFR3,CAMSAP1,MEX3B,FLT1,ANKFY1,NBEA,NPTN,NSG1,GABRA1,GABRA4,GABRB1,GAD2,SALL3,IQGAP2,FAXC,GCNT2,RAB30,GNAO1,GPD2,NUDT21,CECR2,GRB10,GRIA2,GRID1,GRIK2,GRIK3,NR3C1,GRM1,GRM5,GRM7,KIF3A,FAM19A2,IL1RAPL1,KAT7,GUCY1A2,RASSF8,BACH2,MIER3,HLF,HMGB1,HMX1,HNRNPK,NEGR1,AGFG1,DOCK7,IL6ST,KCNA4,KCNC2,KCNH1,KCNJ10,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,LMO1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,RSPO2,OTOGL,NOVA1,HCN1,IGSF11,GPR137C,KCNK10,PBX1,PCSK1,PDE3A,PDGFRA,PDPK1,GNG2,PIK3C2A,FTO,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,PKN2,MAPK8,PROX1,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,RAB3IL1,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,ACER3,PTGR2,CLIP1,AP1AR,AMER2,CSRNP3,ATXN1,ATXN7,ITSN1,FAM102A,DOCK10,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,EMC1,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,EPB41L3,LARP4,NKAIN2,DIP2A,KANK1,GSE1,FGD4,PRRC2C,ATP11A,CAMSAP2,ATMIN,ACSL6,DMXL2,CLASP1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,HEY2,NR2C2,RFTN2,PITPNB,KCNK12,NDRG4,RGMA,PHTF2,RNF146" MicroRNA hsa-miR-181b-5p:TargetScan hsa-miR-181b-5p TargetScan 5.59E-135 3.14E-131 7.91E-134 7.28E-133 285 974 "CPNE2,ASIC1,NDRG2,FMNL2,ADARB2,GALNT16,CCDC85A,BRAP,ERMN,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,ANK1,C6orf89,PPFIA1,GAS7,MADD,CAPRIN2,ASTN1,DDX3Y,ATM,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,HCN2,KSR1,JAZF1,FOXK1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,CDC27,CDH8,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,RAB3C,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,MAP4K4,NIPBL,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,CTNND1,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,CTIF,DNAL1,ELMSAN1,MFAP3L,KLHL3,BLOC1S6,G3BP2,MTX3,ARNT2,DLG2,NR1D2,CDON,DPP6,DPYSL2,DRD1,ABI1,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELAVL2,ELAVL4,ELN,EML1,PAN3,EMX2,EN2,EPB41,DMTN,NCALD,CLVS1,SCML2,ATP8A1,MED12L,FGFR3,CAMSAP1,MEX3B,FLT1,ANKFY1,NBEA,NPTN,NSG1,GABRA1,GABRA4,GABRB1,GAD2,SALL3,IQGAP2,FAXC,GCNT2,RAB30,GNAO1,GPD2,NUDT21,CECR2,GRB10,GRIA2,GRID1,GRIK2,GRIK3,NR3C1,GRM1,GRM5,GRM7,KIF3A,FAM19A2,IL1RAPL1,KAT7,GUCY1A2,RASSF8,BACH2,MIER3,HLF,HMGB1,HMX1,HNRNPK,NEGR1,AGFG1,DOCK7,IL6ST,KCNA4,KCNC2,KCNH1,KCNJ10,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,LMO1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,RSPO2,OTOGL,NOVA1,HCN1,IGSF11,GPR137C,KCNK10,PBX1,PCSK1,PDE3A,PDGFRA,PDPK1,GNG2,PIK3C2A,FTO,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,PKN2,MAPK8,PROX1,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,RAB3IL1,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,ACER3,PTGR2,CLIP1,AP1AR,AMER2,CSRNP3,ATXN1,ATXN7,ITSN1,FAM102A,DOCK10,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,EMC1,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,EPB41L3,LARP4,NKAIN2,DIP2A,KANK1,GSE1,FGD4,PRRC2C,ATP11A,CAMSAP2,ATMIN,ACSL6,DMXL2,CLASP1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,HEY2,NR2C2,RFTN2,PITPNB,KCNK12,NDRG4,RGMA,PHTF2,RNF146" MicroRNA hsa-miR-181d-5p:TargetScan hsa-miR-181d-5p TargetScan 5.59E-135 3.14E-131 7.91E-134 7.28E-133 285 974 "CPNE2,ASIC1,NDRG2,FMNL2,ADARB2,GALNT16,CCDC85A,BRAP,ERMN,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,ANK1,C6orf89,PPFIA1,GAS7,MADD,CAPRIN2,ASTN1,DDX3Y,ATM,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,HCN2,KSR1,JAZF1,FOXK1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,CDC27,CDH8,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,RAB3C,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,MAP4K4,NIPBL,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,CTNND1,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,CTIF,DNAL1,ELMSAN1,MFAP3L,KLHL3,BLOC1S6,G3BP2,MTX3,ARNT2,DLG2,NR1D2,CDON,DPP6,DPYSL2,DRD1,ABI1,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELAVL2,ELAVL4,ELN,EML1,PAN3,EMX2,EN2,EPB41,DMTN,NCALD,CLVS1,SCML2,ATP8A1,MED12L,FGFR3,CAMSAP1,MEX3B,FLT1,ANKFY1,NBEA,NPTN,NSG1,GABRA1,GABRA4,GABRB1,GAD2,SALL3,IQGAP2,FAXC,GCNT2,RAB30,GNAO1,GPD2,NUDT21,CECR2,GRB10,GRIA2,GRID1,GRIK2,GRIK3,NR3C1,GRM1,GRM5,GRM7,KIF3A,FAM19A2,IL1RAPL1,KAT7,GUCY1A2,RASSF8,BACH2,MIER3,HLF,HMGB1,HMX1,HNRNPK,NEGR1,AGFG1,DOCK7,IL6ST,KCNA4,KCNC2,KCNH1,KCNJ10,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,LMO1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,RSPO2,OTOGL,NOVA1,HCN1,IGSF11,GPR137C,KCNK10,PBX1,PCSK1,PDE3A,PDGFRA,PDPK1,GNG2,PIK3C2A,FTO,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,PKN2,MAPK8,PROX1,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,RAB3IL1,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,ACER3,PTGR2,CLIP1,AP1AR,AMER2,CSRNP3,ATXN1,ATXN7,ITSN1,FAM102A,DOCK10,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,EMC1,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,EPB41L3,LARP4,NKAIN2,DIP2A,KANK1,GSE1,FGD4,PRRC2C,ATP11A,CAMSAP2,ATMIN,ACSL6,DMXL2,CLASP1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,HEY2,NR2C2,RFTN2,PITPNB,KCNK12,NDRG4,RGMA,PHTF2,RNF146" MicroRNA hsa-miR-181a-5p:TargetScan hsa-miR-181a-5p TargetScan 5.59E-135 3.14E-131 7.91E-134 7.28E-133 285 974 "CPNE2,ASIC1,NDRG2,FMNL2,ADARB2,GALNT16,CCDC85A,BRAP,ERMN,RNF150,HECW2,KCTD16,OSBPL8,FAM135A,OGT,CDC42BPA,ANK1,C6orf89,PPFIA1,GAS7,MADD,CAPRIN2,ASTN1,DDX3Y,ATM,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,HCN2,KSR1,JAZF1,FOXK1,CACNA2D1,CALM1,PTBP2,CAMK2G,ISPD,CBFA2T2,ENTPD6,LRBA,CDC27,CDH8,DCLK1,LRRFIP1,DLGAP2,NOG,CACNA2D2,RAB3C,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,MAP4K4,NIPBL,CNR1,AKAP5,ABI3BP,BAG4,IGDCC3,CLOCK,HAPLN1,ANKRD44,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,CTNND1,PUM1,GPSM1,DOCK4,HDAC9,GAPVD1,RASSF2,CTIF,DNAL1,ELMSAN1,MFAP3L,KLHL3,BLOC1S6,G3BP2,MTX3,ARNT2,DLG2,NR1D2,CDON,DPP6,DPYSL2,DRD1,ABI1,PDCD6IP,DTNA,E2F5,HIPK3,KLHL5,FSD1L,CELSR3,MBNL2,EGR3,PLXNC1,ELAVL2,ELAVL4,ELN,EML1,PAN3,EMX2,EN2,EPB41,DMTN,NCALD,CLVS1,SCML2,ATP8A1,MED12L,FGFR3,CAMSAP1,MEX3B,FLT1,ANKFY1,NBEA,NPTN,NSG1,GABRA1,GABRA4,GABRB1,GAD2,SALL3,IQGAP2,FAXC,GCNT2,RAB30,GNAO1,GPD2,NUDT21,CECR2,GRB10,GRIA2,GRID1,GRIK2,GRIK3,NR3C1,GRM1,GRM5,GRM7,KIF3A,FAM19A2,IL1RAPL1,KAT7,GUCY1A2,RASSF8,BACH2,MIER3,HLF,HMGB1,HMX1,HNRNPK,NEGR1,AGFG1,DOCK7,IL6ST,KCNA4,KCNC2,KCNH1,KCNJ10,KCNN3,IPO5,L1CAM,MSANTD3-TMEFF1,LMO1,MAPT,MARK1,MBNL1,ADAM11,CHIC1,KITLG,MITF,AFF1,MSI1,RSPO2,OTOGL,NOVA1,HCN1,IGSF11,GPR137C,KCNK10,PBX1,PCSK1,PDE3A,PDGFRA,PDPK1,GNG2,PIK3C2A,FTO,LRP12,SCHIP1,PPARA,PPP2R2C,PPP2R5E,PKN2,MAPK8,PROX1,GDPD1,CNNM2,MTMR10,PTPRE,QDPR,RAB3IL1,CEP97,FIGN,RFX2,RFX3,PRIMA1,LGI2,ROBO2,RORB,ACER3,PTGR2,CLIP1,AP1AR,AMER2,CSRNP3,ATXN1,ATXN7,ITSN1,FAM102A,DOCK10,CHD9,FBXO11,FNDC3A,CNKSR2,CCDC92,BTBD3,EPN2,PKNOX2,CPEB4,EPC1,LIMCH1,FAM126B,NMNAT2,EMC1,MYCBP2,IQSEC2,RBM26,LMO3,CAMTA2,EPB41L3,LARP4,NKAIN2,DIP2A,KANK1,GSE1,FGD4,PRRC2C,ATP11A,CAMSAP2,ATMIN,ACSL6,DMXL2,CLASP1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,NACC2,CBX5,ASXL3,HEY2,NR2C2,RFTN2,PITPNB,KCNK12,NDRG4,RGMA,PHTF2,RNF146" MicroRNA hsa-miR-584:mirSVR_lowEffct hsa-miR-584:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.80E-135 3.82E-131 9.59E-134 8.84E-133 348 1461 "ABAT,ABHD6,TKTL1,CSMD3,TMEM132B,ADD3,BRAP,GRAMD1B,HECW2,WDR35,ALAD,SMIM17,ARHGAP20,PCDH10,BBOX1,UNC79,UPRT,GPAM,USP37,ASPH,BRINP2,TMEM108,ATM,NOL4,DPY19L3,MPDZ,BCHE,BID,ZNF599,OSGIN2,CACNB2,CACNB4,KALRN,PTBP2,CANX,VXN,ISPD,CCNH,MTMR7,SLC16A4,TMEM257,CDC42,CDH2,ZMYM4,LRRFIP1,LOC730101,ZNF445,MAGI1,DLGAP1,CFL2,COPB2,SRSF11,CHM,B4GALT6,NDST3,NRXN3,PPT2,NRXN1,CLTC,FAM19A5,NIPBL,IQCK,ABI3BP,IGDCC3,CREM,ENTPD4,SNCAIP,CSF2RA,LRIG1,FEZ2,FEZ1,LRRC3B,ATRNL1,SIPA1L1,PLXNA4,DZIP3,SDC3,APPL1,PLCXD3,ECE2,BOC,KATNAL2,ARHGAP24,KIAA0586,KCTD8,TMEM170A,SCRN1,PABPC5,GIT2,DNAL1,ARMCX2,ZNF804A,HP1BP3,COPS7A,CEP170,KLHL3,BLOC1S6,ALKBH8,SMG7,RABGAP1L,WDR20,DMD,CASP8AP2,ABI1,EDN1,FAM135B,SYT15,SEMA3D,GOLGA7,TENM1,ELAVL4,USPL1,KCNMB2,GPHN,STX2,EPS8,ETV1,ADGRV1,F5,CLVS1,ZNF461,WAC,ACSL4,ST3GAL6,CEP78,FKTN,TESK2,FECH,FER,FGF1,OLFM1,FGF12,POLK,FOXF2,PCYOX1,SYNCRIP,FOXO3,NBEA,SMC2,ERGIC3,DACH2,CSPG5,STAG2,MEGF10,RAPGEF6,NCKAP1,ZNF559,DISC1,GATM,ADAM28,USP19,GHR,LYVE1,TOX3,TNRC6A,ZNF638,CBX1,LUZP2,KCNMB4,PCLO,RAPGEF4,GRIA4,GRIN2D,GRM3,ZBTB49,MFSD2A,ARHGAP19,TLX1,ZDHHC15,USP51,NEGR1,LRRC75A,C5orf24,RBPJ,DOCK7,PLD5,IL6ST,ITGAV,METTL21A,KCNJ3,STXBP5,HECTD2,NCOA7,PACRG,PIK3AP1,MAOB,MEIS1,PPM1L,AFF1,JAKMIP3,ADAM22,LYRM9,MYO9A,ZNF862,TCEAL5,BEX5,HNRNPM,NAP1L2,NDUFA5,NEUROD1,ALDH1L2,NME4,CNOT4,HCN1,NTRK2,IGSF11,OCRL,OPCML,CLDN11,ZNF827,ZDHHC22,GLIPR1L2,PAK3,CNTN3,PCSK5,PDE4D,SERPINI1,PIK3R1,SLC25A23,HMGCLL1,MTRF1L,PURG,LRP12,PSAT1,IRX1,PPP2R5E,PPP3CA,PKN2,EPDR1,GRAMD1C,DCHS2,BCAS3,SIDT1,CNTLN,BDNF-AS,TMEM260,PTPRE,FAM120C,ZNF493,KHDRBS2,RDX,ZYG11B,GTDC1,RFX2,TTLL7,KIF7,ROBO1,ELP2,NEK11,RPL15,SPIN3,PRR5L,LRRK2,ABCA11P,RTKN,NCBP3,SATB1,FNIP1,ELMOD1,SOX6,SH3BGR,CPEB3,FBXO11,NLGN1,SLC6A11,SIRT2,ATF7IP,SLIT1,CDK5RAP2,KIF13A,LMBRD1,USP33,SOX2,KDM3A,ERC1,RBM26,LMO3,TROVE2,STAU1,SEPT8,NECAB1,PRRC2C,FNDC9,PLCB1,TACC1,DDHD2,CAMTA1,TAF9,VWA3A,CUX2,TRIM2,TCF12,AKNA,GPRIN3,PCDHA5,FAM200B,ZNF106,HHIP,TIAM1,TK2,TLR4,PARD3,KAT6B,PIK3R5,TPM3,DOK6,ZNF384,RGMB,PRMT8,SMUG1,AMACR,STXBP4,ANKRD20A2,TTC3,PRR18,ZKSCAN5,HEPACAM,UBE2H,UBE3A,FLRT2,PLEKHH2,USP1,ZNF709,CLDND1,SF1,ZIC2,ZNF711,ZNF24,ZNF138,REEP1,ZNF189,ZFAND5,UPF3A,DHX33,WNK1,PMEPA1,CADM2,CSDE1,PRDM10,CAB39L,GOPC,FZD3,UBE3B,PHTF2,CERS6,NLRP3,FRMD6,NETO1" MicroRNA hsa-miR-379*:mirSVR_highEffct hsa-miR-379*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.06E-135 3.97E-131 9.95E-134 9.16E-133 330 1315 "CLK4,NCKAP5,ERMN,PTCHD1,KIDINS220,RTL9,CC2D2A,ALCAM,LRCH2,GPAM,DGKD,VAT1L,BCAS1,TNRC6C,APP,MIER1,CAPRIN2,ASPH,ZBTB10,NCOA1,NUMB,TMEM108,SLC4A4,ATP1B3,NOL4,DPY19L3,SEC11C,AP1M1,SGCE,WASF1,CACNB2,KALRN,MTMR7,CD86,SYNGR3,CDC42,CDH2,LRRFIP1,LARGE1,MAGI1,DLGAP1,SRSF11,CHN1,NDST3,PLAA,NRXN1,FBXO7,ARMC8,AKAP6,COL4A5,SLC25A27,AKAP5,ACBD5,SLC35F1,SEC31B,CLOCK,RBM39,SH2B1,FEZ1,CSNK1G3,ATRNL1,PDE4DIP,FAM169A,DZIP3,CTNND1,RIMS2,CCDC144A,CYBB,KATNAL2,LIN54,TOMM20,PABPC5,ELMSAN1,C8orf34,HP1BP3,CEP170,GSDME,SPOCK3,RABGAP1L,SEC16A,GRIN3A,DMD,DMTF1,RCAN1,ECM2,DYRK1A,ABCC9,EDNRB,HIPK3,FCF1,RASGRP1,FSD1L,YAF2,MRO,EIF4G2,TENM1,PLEKHA1,TMEM35A,C8orf37,CALCRL,EN2,LRRC17,ENPP6,SRRM1,CEP85L,RRAGB,ABCA8,FAM198B,CHST15,SEC24B,FER,KIAA1109,POLR1B,CAMSAP1,POLK,SUCO,IP6K2,NELFCD,C2orf88,PDLIM5,TPK1,ATP6V1H,DACH2,PHYHIPL,GABRG2,CAB39,RAPGEF6,ATP8A2,INPP5K,ARFIP1,PPARGC1A,SPIN1,GLS,ZNF638,KIAA1958,KDM2B,HTATSF1,ADGRA3,GRM3,GRM7,PSIP1,GUCY1B1,MAP4K5,WIF1,FRMD3,ATXN2L,HMGB1,AGBL5,MSL1,LIX1,IL11RA,ZNF678,LRRTM3,KCNK1,PAXBP1,HECTD2,MAP4,MBNL1,IL17D,CHIC1,MEIS1,MEIS2,MITF,WDR49,CD200,MSI1,ADAM22,BCO1,MYO9A,HNRNPM,IDNK,NEFM,NEK1,DNHD1,CLEC9A,NRCAM,GLIPR1L2,CNTN3,SLC10A4,GPR85,GNG2,OLA1,SNX10,RETREG1,HMGCLL1,PMP22,SCHIP1,EPB41L4B,MINDY2,PPP2R2C,CRLS1,PPP3CA,KANSL1,HYDIN,SIDT1,MDGA2,PSMD13,CNTLN,BDNF-AS,TMEM260,PTPRB,OCIAD1,PTPRD,C1orf109,PPP2R3C,PID1,USP47,ACSS3,KHDRBS2,RDX,SLC6A15,GTDC1,FIGN,RFX3,ARHGEF10L,SEC61A2,SLC25A36,NUDT11,PBRM1,RNASEL,ZFHX4,ZNF532,RAVER2,CARF,RORB,ATP8B4,ADAL,ACER3,LRRK2,SALL1,SEMA6D,SATB1,HOGA1,SCN3A,LINC00461,SCP2,FNIP1,ELMOD1,SUPT20H,SGK1,ITSN1,CHD9,NLGN1,CLSTN1,WDR47,RUFY2,KDM4D,SEPHS1,SHANK2,SLC12A2,SLC15A2,ATF7IP,SLCO1A2,SPHKAP,ZFP1,SMARCA4,CMTR2,SNRPN,UNC80,SOX3,SP4,CLUAP1,ENKUR,KDM4C,RBM26,ATP10B,TROVE2,NKAIN2,ELOVL4,TTBK2,PHLDB1,SYNE2,VPS13A,SYPL1,MTCL1,CAMTA1,MCF2L,EXOC7,FAM208A,TBCEL,TMEM136,ANO4,CUX2,TCF7L2,ZEB1,RPGRIP1L,SYNE1,PCDHB10,PCDHB6,PUM2,FRYL,TEX15,PMS2CL,HHIP,SLC44A1,TJP1,TLL2,HEY2,TPM4,RGMB,TRO,TRPC1,CLHC1,CADM1,UBE3A,AMOT,UGT8,PLEKHH2,WRN,ZNF711,MICU3,KCNT2,MKRN3,ANKS1B,FTSJ1,PLPPR5,CADM2,PRDM2,RGMA,STOX2,RNF103,GOPC,AMN1,DOCK8,PHTF2,JMJD1C,SSPN,FXR1,NETO2,NETO1" MicroRNA hsa-miR-888:mirSVR_highEffct hsa-miR-888:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.56E-135 4.81E-131 1.20E-133 1.11E-132 365 1605 "CLK4,NCKAP5,CSMD2,CCDC85A,ADD3,CDC7,SORCS1,ERMN,ADORA3,ADRB2,BEND6,SLC44A5,INTS2,ALCAM,ARHGAP20,GPRASP2,CDC42BPA,DPP10,LRCH2,GPAM,ALS2,API5,MIER1,ARRB1,MARCH3,ASPH,NUMB,SLC4A4,ATP1B3,RNF182,N4BP2L1,BARD1,ZNF599,SYNJ1,SCAPER,CACNA1B,CACNA1D,KALRN,VSTM2A,CLDN10,KRIT1,LRBA,CDC42,LGI1,MAGI1,RCBTB2,SRSF11,SYNPR,KMT2C,IGFBP7-AS1,DGCR9,QKI,CNGA3,COL4A5,SLC25A27,SLC4A8,ZNF521,CP,PREPL,C2CD2,ENTPD4,HAPLN1,ANKRD44,NCOR1,FEZ1,LRRC3B,SOCS5,PDE4DIP,SLITRK5,ST18,DCAF4,USP6NL,EDRF1,CX3CR1,CCDC144A,HDAC9,GPRASP1,ARHGAP32,TBC1D5,DGKB,HP1BP3,FBXL5,MAGI2,PLPPR4,SPOCK3,G3BP2,WDR20,FAM107B,NR1D2,DMTF1,DNAJB6,DNM1L,E2F5,E2F6,WDPCP,FAM135B,FCF1,SEMA3D,KLHL5,YAF2,PHF20L1,APH1A,MBNL2,KMT5B,ELAVL2,PLEKHA1,EN2,VPS13B,EPHA5,SRRM1,DENND4A,DUSP27,RCSD1,SIRPB1,ADGRV1,ZIC4,DLC1,CEP78,TESK2,GORAB,FGF14,FOXG1,IP6K2,SLC37A3,AFF2,FOLH1,JKAMP,STAMBP,ATP2C1,STAU2,FYB1,DKK3,GABRA1,HRASLS5,TRAF3IP2,AHCYL1,ARPP21,ERAP1,MTHFD2,LRRC37A6P,DNER,ARFIP1,PPARGC1A,RNPS1,GPR75,GLS,TOX3,TNRC6A,DCLK2,GPD2,LILRA1,LILRA2,GPR12,GPR37,GRB10,GRIA2,GRIN2C,MAP4K5,PACSIN2,HLF,ELOVL5,GABARAPL2,HSP90AA1,CELF5,ZNF546,ZIC5,RBPJ,DOCK7,KNDC1,IGSF1,LRRTM3,NME9,METTL21A,KCNA4,KCND2,KLHL23,KCNK2,KIF5C,STXBP5,STMN1,HECTD2,C2orf80,GPR155,MAP2,AQP11,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,SESN3,ADAM22,ZNF92,MXI1,MYCN,NDP,NDUFA5,NEFM,NEK1,NF1,NFE2L2,CNOT4,NUCB2,OCRL,OLR1,CLDN11,GPR137C,PCMT1,CDK18,PDE4D,GNG2,PFKFB2,SNX10,RETREG1,XRN1,PLP1,SMIM7,HMGCLL1,TRHDE,MAPKAP1,EXOSC10,EPB41L4B,TNPO2,MED1,PPP2R5C,PRKACB,PKN2,PRKCZ,DIRAS2,SNRK,ANKHD1,ELOVL2,TMEM260,PTPRN2,PTPRO,TMEM231,ACSS3,CCDC40,FAT4,RADX,KHDRBS2,MSANTD2,SLC6A15,REV3L,RGR,RGS3,RGS4,RIT2,SEC61A2,SLC25A36,RPRD1A,ZNF532,SETD5,EXD2,CCDC25,ELP2,PCMTD2,RPE,RPL15,UEVLD,FBXW7,ACER3,WLS,KCNIP1,RTN1,RXRG,NCBP3,SCN8A,FNIP1,ELMOD1,GALNT10,SUPT20H,HSPA4L,ITSN1,CHD9,FHOD3,SYBU,PAAF1,EPN2,RUFY2,BTBD7,SLC22A4,CPEB4,ZNF667,SMARCE1,ANKRD36,RIMS1,MBD5,CABCOCO1,UNC80,USP33,ZCCHC24,NMNAT2,SPP1,KDM4C,KIF1B,MCF2L2,RBM26,SPART,LMO3,CLASP2,TROVE2,SSTR1,ZC4H2,SS18,ERBIN,PRRC2C,VAMP1,PLCB1,SYPL1,SYT1,SYT4,MTCL1,CAMTA1,ADGRL3,TBCEL,DMXL2,SATB2,WASHC4,CLASP1,SYNE1,SIK3,GZF1,TK2,TMPO,KAT6B,C9orf85,RGMB,SYNPO2,RUNDC3B,AMACR,DCBLD1,FAM155A,UBE3A,ZNF709,BCL2L13,MEAF6,ZNF711,ZNF19,KCNT2,ELFN1,LYPD6,ZBTB38,ZNF189,UPF3A,WNK1,EMSY,LRP8,PRDM8,PRDM10,RNF103,HPS4,NAV2,WNK3,PLSCR4,GOPC,FAM13C,FZD3,DOCK8,PAK5,JMJD1C,ZNF248,SLC39A12,SSPN,IFT88" MicroRNA hsa-miR-362-5p:mirSVR_lowEffct hsa-miR-362-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.02E-135 5.07E-131 1.26E-133 1.16E-132 405 1959 "KCNH8,ABR,SYN3,ABHD6,NCKAP5,ACTN2,CSMD2,GALNT16,TMCC3,GALNT13,ESYT2,KIDINS220,MTUS1,CC2D2A,ADGRF5,CEP126,ABCD2,CARNS1,LRCH2,USP28,PPFIA1,EPB41L5,DGKZ,PHYHD1,CACHD1,APP,SHTN1,ZFYVE28,ARNTL,PLA2G4C,CADPS,CAPRIN2,ZBTB10,NCOA1,TMEM108,ATM,EIF4G3,ATP6V0A1,BACH1,BCHE,MIR9-3HG,PROM1,CDK5R1,FUBP1,NIPA1,KALRN,CAMK2A,VXN,VSTM2A,CARS,CBR1,RGN,INA,CDC27,LGI1,LOC730101,MAGI1,IGFN1,NUMBL,GPR37L1,CHGA,CASC2,MS4A7,B4GALT6,ZFYVE9,CLCN3,CLTA,QKI,NIPBL,COL4A5,LETMD1,SLC4A8,COX4I1,BAG4,MYRIP,MFSD4A,CPS1,SEC31B,C2CD2,CREB5,CS,ATRNL1,FAM169A,RUBCN,CCDC144A,NOS1AP,FGFR1OP2,DCAF8,ZNF337,MATR3,DGKB,AIF1L,DNAJC6,ELMO1,SV2B,NTM,GRIN3A,DMD,NR1D2,DTNA,DNAJB6,E2F5,E2F6,USH1C,ANKRD46,SGK2,FCF1,FRY,EFNA3,RBM12,PHF20L1,EGFR,MBNL2,KMT5B,ABI2,AASS,PLEKHA1,PCOLCE2,PAN3,RCAN2,EPS8,ERCC2,MRPL10,ETV1,RTN3,ANKMY1,MRVI1,F5,REEP2,ARMCX1,FABP7,CEP78,TESK2,ZNF589,SEC24B,FER,FGF1,FGF12,POLK,UBE2E3,MEX3B,FOXF2,PCYOX1,VTI1B,SYNCRIP,FLT1,C2orf88,WDR83,SORBS1,APOPT1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,NSG2,PHYHIPL,ZMAT1,DKK3,DENND2A,BRPF3,IP6K3,ZNF559,DISC1,DNER,IGSF5,NEU3,GFRA2,MALT1,GJB1,GLI2,GLS,DCLK2,GPR12,EML4,STMN2,GRIA2,GRIA4,GRIK2,PRDM5,GRM7,RNF165,AP4S1,ATOH8,MAEL,RASSF8,HAS2,ATXN2L,HPSE2,HNF4G,MSL1,IDH3B,C2orf72,RBPJ,NIM1K,LIX1,ITPKB,KCNC2,KCNK1,KIF5C,KTN1,LAMP2,HECTD2,SMAD9,MAP6,MATN2,MBD1,MBNL1,SYT9,TM6SF1,MDM4,LRP1B,MEIS1,KCTD6,MIA2,MITF,WDR49,SESN3,BLOC1S2,MYT1,NEFH,NEK1,NFE2L2,NOVA1,CLEC9A,SLC11A2,NUCB2,OLR1,GLIPR1L2,CNTN3,DPY19L2P2,PDE1C,PDE3A,PDGFRA,GPR173,SERPINI1,FAM218A,A2ML1,KCTD15,PLP1,HMGCLL1,PLXNB1,PMP2,PRRX1,ING3,SPATA6,RETREG2,FAT3,NXPH1,DRAM2,PPARA,PPP3CB,PKN2,PRKCZ,DCHS2,SAMD9,PTAFR,ZIK1,PTPRG,PTPRZ1,TMEM145,TUG1,PPP2R3C,RAD52,FAM66C,SH3TC2,ENOX1,ZNF493,OXR1,RASGRF2,RBBP8,TRIM68,RET,FIGN,RFX3,RFX5,RGR,RGS3,RIC8B,TMEM100,PGBD4,UEVLD,ZC3H14,GLDN,PRR5L,LRRK2,CNTNAP3,RPS20,ABCA11P,ZNF568,FAM182A,SCP2,TRIM46,SCAF8,SH3GL3,FERMT1,DZIP1,URGCP,SLC6A1,PKNOX2,LRRC55,SLC6A11,CCDC88A,SLC11A1,BTBD7,CPEB4,SMARCE1,RCOR3,IFT122,CABCOCO1,FAM126B,SOX2,KIF21B,BDP1,ZHX3,SP4,NMNAT2,CLUAP1,ENKUR,MYCBP2,IDI2-AS1,DBNDD2,CDK19,TSPYL2,SPART,SRPK2,POGZ,THSD1,SMOC1,MAPK8IP3,ELOVL4,ARHGEF9,VPS13A,SYN1,SYN2,TAC3,KAZN,DDHD2,CAMTA1,TAF9,EXOC7,CAMSAP2,UNC5D,IQCE,EHBP1,DMXL2,SATB2,RPGRIP1L,HIF3A,FAM200B,PMS2CL,CRB1,GZF1,MTMR14,HEY1,ACTR6,RIMBP2,KCTD2,R3HDM1,TPD52,C9orf85,WBP2,ZNF384,PRMT8,TRIO,STXBP4,TRPS1,PPIL6,FNDC5,RFTN2,CADM1,UBE3A,GORASP1,SLAIN1,BCL2L13,VAV1,RICTOR,SLC13A3,XPO1,ZIC2,TRIM9,ATP6V0E2,FMN2,LYPD6,ZBTB38,TMEM237,ANKS1B,SMARCAD1,STOX2,RNF103,ADAMTS9,FAM47E,WNK2,PDSS2,EPM2A,RGS7BP,FAM13C,HNRNPA3,ZNF248,VANGL2,MSRB3,KLHDC1,IFT88,NETO1,FAM198A,SPATA13" MicroRNA hsa-miR-92b:mirSVR_lowEffct hsa-miR-92b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-134 5.78E-131 1.44E-133 1.33E-132 367 1623 "VWA5B2,RBM10,AS3MT,ADARB2,ELFN2,CCDC85A,ADD3,PWWP2A,BEND6,MTA3,GPR158,HACE1,OSBPL8,BCAR3,PCDH10,UNC79,AMPH,LRCH2,LCORL,PPFIA2,PKP4,ANXA7,APBB2,MAGEE2,DDO,AQP4,PPP4R4,CASK,RGS20,CDK13,DACT3,ZBTB10,NCOA1,ASTN1,ATP1A2,SLC4A4,ATP1B3,DOCK11,BACH1,SNAI3-AS1,RGS9,FUBP1,BSN,CDK5R2,BTRC,VSTM2A,SLC16A4,TMEM257,CDC42,LGI1,L3MBTL4,DLGAP2,CLGN,CHGA,CASC2,JAM2,PLAA,KIAA1549L,CLTA,NGEF,LY86,AKAP7,PCYT1B,ARMC8,BTF3L4,AKAP5,ABI3BP,AHCTF1,MYRIP,ZNF521,CHD1L,SEC31B,CREM,AKAP12,CLIP3,AATK,ARHGEF10,MICAL2,SIPA1L1,PHACTR3,DZIP3,RIMS2,PPP6R2,ECE2,NOS1AP,ARHGAP24,DCAF8,EARS2,LIN54,MATR3,DGKB,BRINP1,GIT2,SIRPA,DCC,HP1BP3,KIAA0753,DDX46,SNAP91,NTM,WDR20,NR1D2,ABI1,MAMLD1,ABCC5,EDIL3,EFNB3,FAM13A,PHF20L1,ABI2,EIF4G2,SORBS3,TENM1,STARD3NL,EIF1,EMX2,EPS8,ERBB4,MRPL37,DNAJC27,CLVS1,ZIC4,SCML2,DLC1,RACK1,ST3GAL6,FKTN,TESK2,FECH,FER,MED12L,FGF1,FGF13,PRKAG2,MEX3B,FOXG1,FOXO3,EFCAB2,POMT1,FAM49B,USP21,KHDRBS3,STAG2,MEGF10,GABBR1,GABRA2,HBS1L,AHCYL1,MTHFD2,LRRC37A6P,KIAA1841,GATM,DBF4,GLS,ZNF638,PRRC2B,GPM6B,FUT10,EML4,GRIA4,GRIK2,GRM8,GSTT2,LINC01551,SOX21,GUCY1B1,ZHX1,HMGCR,LRRC75A,HTR5A,EID2B,C5orf24,INSM1,ZNF385B,JAK2,METTL21A,KCNA1,KCND2,KCNJ3,KCNMA1,KIF5C,IPO5,INSYN2,PAXBP1,HECTD2,FGFBP3,NCOA7,PACRG,C1orf194,MAP4,MARK3,TM6SF1,MEIS1,AFF1,MMP16,MYH3,BEX5,NAP1L2,NEK1,NELL2,NEUROD1,NFIA,NFIX,NKX2-2,NODAL,CNOT4,NPY,DNHD1,NPTX1,SLC11A2,HCN1,NUCB2,OPHN1,OXTR,P2RY1,PCDH8,PCDH9,PCSK5,PDE4D,PIRT,PDGFRA,PDYN,PFKFB4,CDK14,XRN1,FAM216A,PLP1,PCDH18,PMP22,SPATA6,EPB41L4B,PPARA,PPM1B,CRLS1,PPP2R5C,PPP2R5E,PPP3CB,NKAIN4,RANBP3L,PRKACB,PRKCG,PKN2,EPDR1,DCHS2,LAMA1,MDGA2,CNTLN,OCIAD1,PTPRG,STRC,MARCH1,SLC25A48,USP47,RAD51D,FAM184A,ZNF493,RBBP6,RADX,KHDRBS2,SLC6A15,GTDC1,RLBP1,SLC25A36,ZFHX4,RERGL,ACER3,STK32B,LRRK2,LGR4,RPS20,SYNDIG1,RYR3,ZNF331,CCDC112,MIR124-2HG,SEMA6D,CSRNP3,ATXN7,LINC00461,RASA3,SGK1,SCG5,ITSN1,FERMT1,NTNG1,SHC4,CHD9,FBXO11,SYBU,ZNF365,FAM81A,SLC6A1,SEPHS1,ATF7IP,SMARCC2,SORCS3,IFT122,LMBRD1,SNRPN,MYT1L,SOX11,DOK5,CLUAP1,ENKUR,HECW1,TSPYL2,MCF2L2,RBM26,SRPK2,TAB2,EPB41L3,ZC4H2,SS18,ERBIN,SEPT8,STXBP1,VPS13A,PLCB1,ANKRD28,MMS19,ANKRD12,DDHD2,KLHL4,TBX15,ATMIN,DMXL2,ZEB1,SYNE1,NAT16,RALYL,SLC35G2,TEK,SIRT1,ZFPM2,ITGB3BP,AP4E1,ZMAT3,ARL10,TMOD1,CSMD1,TPM1,PDSS1,STXBP4,TSC1,SSBP2,CADM1,PITPNB,PLEKHH2,XRCC4,ZNF28,ELFN1,SPHK2,REEP1,MEIS3,PMEPA1,ZXDA,PRDM2,TMEM178A,C12orf4,FZD3,KAT6A,FBXO36,FAM219B,JMJD1C,MSRB3,NETO1,SENP7" MicroRNA hsa-miR-135b:mirSVR_lowEffct hsa-miR-135b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.22E-134 6.88E-131 1.71E-133 1.57E-132 394 1861 "DPF1,NCKAP5,SYS1,FMNL2,ADARB2,KLHL32,TMEM132B,GALNT16,ADCY2,ADD1,ADD2,PWWP2A,BEND6,OLMALINC,SLC44A5,GPR158,HACE1,OSBPL8,CC2D2A,PLA2G6,TAOK1,SEMA6A,UNC79,ZFAT,CDC42BPA,ANK1,EP400,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ALS2,PRX,CAPRIN2,NCOA1,DDX3Y,ATP2B2,ZNF583,MTMR9,NOL4,DPY19L3,LINC00847,HCN2,SYNJ2,MTMR2,GYG2,BSN,CFAP410,CACNA1E,CAMK2D,TRIM41,VXN,NFS1,SHISA7,METTL6,P2RX6,CD86,ZBED1,CDH8,LRRFIP1,LGI1,MAGI1,CDO1,CCPG1,FOXN3,CHM,CASC2,JAM2,NDST3,CPNE6,NRXN3,IGFBP7-AS1,CLCN3,SLC24A2,TJP2,RAB26,CNGA3,CNN3,IQCK,PCYT1B,AKAP6,SLC4A7,SLC4A8,ABI3BP,MYRIP,HS3ST5,ZNF385A,SLC35F1,PNKD,RNF14,NCOR1,GDA,SNCAIP,CSF1,PHF14,ARHGEF4,RIMS2,DOCK4,KATNAL2,GAPVD1,RIPOR2,DCAF8,TOX,PHF19,MAML1,DBI,ARMCX4,ZEB2,PLEKHM1,RUSC2,C2CD2L,RHOBTB1,SACS,SV2B,NTM,RABGAP1L,WDR20,DLG2,DYNC1I1,DNM2,DOCK2,DMTF1,SLC12A6,DPH1,CASP8AP2,SLC25A18,DRD1,DRP2,DTNA,FAM78B,WDPCP,EDN1,ATL1,FCF1,MRO,KMT5B,LPAR6,COPS4,RGS17,DCTN4,EIF1,EPB41,APC2,VPS26C,DNAJC27,SIRPB1,EXTL2,WAC,ATP8A1,CEP78,FCGR3A,GORAB,FER,AMOTL2,IP6K2,RGPD5,FLT1,SYT3,C2orf88,NSG2,DACH2,STAG2,CHL1,GABRG1,GAD1,AHCYL1,ZMYND11,B4GALNT1,RAPGEF6,GALR1,SALL3,ZNF274,DISC1,CPLX1,FAXC,ALDH1L1,CYP46A1,LYVE1,GK,HPGDS,DBF4,PCDH11X,STARD3,ZNF638,DCLK2,LNX1,ADGRA3,LILRB4,PRUNE2,GPR22,NUDT21,PCLO,GRIA2,GRIN1,BTN2A1,KIF3A,BVES,ADAMTS6,MAP4K5,RASSF8,ZHX1,ARHGAP19,INSYN1,MIER3,HNRNPK,NEGR1,AGFG1,SHISA6,MSL1,FAM95B1,GAREM2,RBPJ,LRRCC1,KCNB1,KCNJ3,KIFC3,KIT,CYP27C1,KTN1,HECTD2,MAP2,MAP4,MARK1,MAT2A,MATN3,MEF2C,MEIS2,MEST,KCTD6,MID1,PPM1L,POC1B,MN1,WDR49,MOV10,SAMD5,RSPO2,HS6ST3,NF1,ALDH1L2,DNHD1,NTRK2,NUCB2,ODF2,OMG,GPR137C,PRTG,PDE1A,PDE2A,PDYN,GPR85,SSH1,PIK3C2A,ZNF655,CCSER2,SNX10,GPSM2,ST8SIA5,PLXNB3,ANKRD16,TNPO2,KANSL1,SNRK,WDR25,CNTLN,UHRF1BP1,BDNF-AS,ELOVL2,PTPRB,PTPRE,FAM120C,SH3TC2,OXR1,RBBP6,BSDC1,MSANTD2,ZYG11B,REV3L,PRIMA1,TTLL7,SEC61A2,RIC8B,SETD5,GSTCD,ROBO2,SPIN3,ZNF671,ATP8B4,GLDN,ACER3,TCP11L1,ZNF331,SEMA6D,SCN2B,FAM19A1,LINC00461,SCP2,ELMOD1,MRAS,ITSN1,FAM102A,HKDC1,NLGN1,DZIP1,CLSTN1,SLC1A6,FAM81A,SHANK2,KBTBD4,ELMO2,ATF7IP,SLN,SMARCA4,SORCS3,RCOR3,MAPKBP1,UNC80,SCN3B,WDTC1,MYT1L,TRERF1,SOX2,KIF21B,NMNAT2,GLT8D1,TEX2,DBNDD2,KIF1B,IQSEC2,NFASC,ATP10B,ZC4H2,FGD4,JMJD6,PRRC2C,ZFR2,VPS13A,PLCB1,COBL,DDHD2,CAMTA1,DNMBP,TCF4,TCF7,ZEB1,RPGRIP1L,RALYL,ARHGEF12,PCDHA5,AHCYL2,DICER1-AS1,ZFPM2,GPR161,TIAM1,MTMR14,TLL2,TNS1,RBFOX2,TPM1,PRMT8,NEIL2,TRO,STXBP4,FNDC5,RUSC1,ANO5,UBE2H,OSBP2,PLEKHH2,NSD2,SLC13A3,ZIC3,ZNF28,ZNF154,EML6,SPIRE1,SMARCAD1,SYNC,PRDM2,SLC38A1,ADAMTS9,FAM47E,TRIM16L,MPPE1,FZD3,HNRNPA3,PHTF2,FBXO36,NUP214,ACTR3B,TRAM2-AS1,MSRB3,TTC7A,FRMD6,CBLN2,SOCS4" MicroRNA hsa-miR-708:mirSVR_lowEffct hsa-miR-708:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-134 7.97E-131 1.97E-133 1.82E-132 374 1685 "KCNH8,ASPHD1,NBAT1,NDRG2,ADCY2,SLITRK1,ADCY6,CCDC85A,ADD2,SORCS1,PLEKHH1,NLGN4X,AP2A2,AP1B1,ZNF608,GPR158,HECW2,CC2D2A,AK2,ADGRF5,PCDH10,KIF6,CDC42BPA,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,VAT1L,CDC14B,CDK10,IGDCC4,MARCH3,ASPH,BRINP2,STX16,N4BP2L1,ADAM15,KSR1,CDK5R1,SYNJ2,CASTOR3,MTMR2,NIPA1,BTRC,CACNB4,KALRN,NGB,VXN,KYAT1,CBFA2T2,ENTPD6,LRBA,MAGI1,FOXN3,CHN1,PLEKHB1,CASC2,SYNPR,JAM2,TAOK2,RAB28,KIAA1549L,FBXO7,QKI,TMEM184B,LY86,FAM149A,WHRN,AKAP5,TOGARAM2,MFSD4A,CREM,SH2B1,CRMP1,HAPLN1,CLIP3,AATK,ARHGEF10,MICAL2,ATRNL1,SIPA1L1,GALNT9,VCAN,PDE4DIP,SLITRK5,PITPNM3,SDC3,CMTM5,CTH,ECE2,CCDC144A,NOS1AP,ARHGAP32,IST1,ELMSAN1,DGCR5,HEPH,MYEF2,HP1BP3,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DYNC1I1,CDON,DPH1,DRP2,E2F6,FAM135B,PHC2,HIPK3,TMTC1,CACNG7,SH3GLB1,EFNB3,FAM13A,EGR3,RASA4,RCAN2,SEZ6,EPHB1,KCNMB2,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,WAC,PTK2B,TUBB4A,ATP8A1,FCGRT,FKTN,STRADA,FDFT1,ZNF589,MED12L,OLFM1,FGF11,MAD2L2,SUCO,UBE2E3,C1orf61,PCYOX1,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,UFM1,USP21,ZNF605,NSG2,ZNF512,DKK3,MEGF10,GAA,GABBR1,CHL1,GABRB3,ARPP21,GAP43,DISC1,WASF3,GATM,ALDH1L1,SESN1,KIRREL3,DHRS4,RAB30,TOX3,TNRC6A,MSL3,ZNF638,ADGRA3,LILRB4,PRUNE2,GRIA4,GRM1,PRDM5,GRM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,WIF1,MUM1,PTGDR2,HMGCL,AGBL5,HNRNPK,DHX35,SHISA6,SHISAL1,ZIC5,DOCK7,PLD5,IGSF1,DIPK1A,LRRTM3,JAK1,METTL21A,KCNA6,KCNF1,KCNK1,KCNK3,KCNN2,CREG2,IPO5,CYP27C1,L1CAM,SYTL4,LDLRAD3,SCAMP5,MOG,TAGLN3,MYH7,HNRNPM,NCAM1,NEUROD1,NF1,NNAT,NOS1,NUCB2,GPR88,OGG1,CDK18,PDE3B,PDE1B,GNG2,BEST3,PFKFB2,PFKFB3,OLA1,CDK14,GDAP1L1,PIK3R1,ZFYVE21,XRN1,KCTD15,ST8SIA5,EPN1,PURG,PRIMPOL,ING3,TNPO2,POLR2F,POU6F1,PPARA,CRLS1,PTPA,PRKAB2,MAPK4,EPDR1,MASP1,TMEM104,STK32A,PEX2,TMEM231,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RFX4,RFX5,RGS3,RGS4,RNF220,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,ATP8B4,MAP6D1,NCBP3,FAM192A,CSRNP3,ATXN1,PRCD,SCP2,SEC14L1,SOX6,SELL,GALNT10,NLGN4Y,SH3GL2,FERMT1,DOCK10,NTNG1,SYBU,ABLIM3,SLC1A7,URGCP,PREX2,SLC6A1,LRRC55,SLC8A2,SLC8A3,ARHGEF40,ATF7IP,NAXD,ZFP1,GKAP1,SMARCC2,RCOR3,INAVA,SNRPN,UNC80,SP4,KDM4C,IDI2-AS1,IQSEC2,ZBTB43,RBM26,CLASP2,COLGALT2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,SYT11,JMJD6,PRRC2C,ZFR2,ARHGEF9,VPS13A,SYN2,POPDC3,ROBO3,DNMBP,VWA3A,TCF4,SYNE1,CCDC173,AP4E1,GZF1,ASXL3,FAM124A,NPL,TPM3,NEIL2,STXBP4,TRPC3,TRPS1,SSBP2,RFTN2,PRR18,UBTF,DNAJC12,SF1,ZNF19,SLC26A10,AMZ1,PLPPR5,URM1,FAM47E,WIPF2,ST7,UBE3B,FAM198A,JPH3" MicroRNA hsa-miR-378*:mirSVR_lowEffct hsa-miR-378*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-134 8.06E-131 1.99E-133 1.83E-132 400 1916 "ACLY,EMILIN3,SYS1,ACTN2,ESYT2,AP2A2,MTUS1,HECW2,AK2,C1QTNF1,SMIM17,CEP126,EP400,PI16,MYH7B,PARG,EPB41L5,UPRT,ARHGDIG,MARK4,ASPH,NCOA1,CCAR2,ATP2B1,ATP2B2,SLC2A11,N4BP2L1,DPY19L3,ATP6V0A1,DOCK11,ADAM15,BCHE,CFLAR,BMPR1B,CDK5R1,SYNJ1,SCAPER,MMD2,CACNA1E,CAMK2G,TRIM41,BRSK2,SPAG9,METTL6,MTMR7,CBFA2T2,CDH8,CDH18,LGI1,L3MBTL4,TIGD7,NUMBL,CACNA2D2,DIS3L,CHM,CHRM1,CASC2,CNOT8,CLTA,SULT4A1,IGLON5,WHRN,LETMD1,COL11A2,SLC4A8,CREM,ANKRD44,NCOR1,CLIP3,ABCG1,SNCAIP,FEZ1,CSNK1E,ATRNL1,VAC14-AS1,PDE4DIP,SDC3,APPL1,RIMS2,ZSCAN23,NOS1AP,DOCK4,MYADM,FGFR1OP2,RIPOR2,ZFYVE16,LONRF1,DGKG,TMEM170A,AIF1L,PLEKHM1,HEPH,MYEF2,KIAA0753,LYPD1,ZC3H11A,GUCD1,PARD6A,SPOCK3,SV2A,RABGAP1L,TMCC2,FAM107B,ARNT2,KBTBD11,DLX1,GRIN3A,DMPK,HS3ST2,RPS6KL1,DOCK2,DPP6,SLC25A18,DRD1,ACOT8,RCAN1,DTNB,MAMLD1,DYRK1A,ABCC5,DNM1L,SNX29,CNNM1,SEMA3D,KLHL5,RBM12,GPR61,TENM1,C3orf18,PAN3,EPB41L1,COQ7,KCNMB2,ANKRD13B,IGSF6,VPS26C,ADGRV1,F3,PTK2B,FKTN,GTF2IRD2,POLR1B,FGF11,FGFR1,BAIAP2,TMEM164,POLK,SUCO,HPCAL4,FOXG1,FOXM1,FLNC,FLT1,SORBS1,TMEM107,ZNF605,ERGIC3,NSG2,B3GAT1,DOT1L,TVP23A,HRASLS5,GABRA3,GABRA5,AHCYL1,FAM120B,ARPP21,ERAP1,TMEM8B,ATP8A2,GCNT2,TUBGCP4,SULT1C4,GFRA2,PCDH17,CSDC2,ZNF276,ZNF638,GNAS,ZNF782,PRUNE2,PRLHR,LPAR4,CECR2,RAPGEF4,GRIA1,GRIA2,DIDO1,GRM2,LINC01089,CLASRP,ZBTB49,AP4S1,GUCY1A2,IRAK3,MAEL,RASSF8,NCKAP1L,ARHGAP36,HMGCL,HNF4G,ZNF491,HSP90AA1,FAM95B1,IL6ST,LRRTM1,SLC35G1,OLFM3,KCNC1,KCNK2,KCNMA1,GATD1,A1BG-AS1,L1CAM,NCOA7,SMAD9,MATN2,MBP,ADAM11,MEIS1,MIA2,KITLG,MITF,XRRA1,WDR49,MOG,MYO9A,ZNF862,NEK1,NELL2,NF1,ALDH1L2,NFYA,NNAT,NODAL,NOVA1,PCBP3,OLR1,OPCML,OXTR,P2RX7,PAH,PDE4A,PDYN,PFKFB2,SERPINE2,NALCN,A2ML1,XRN1,GPSM2,ZNF426,MTRF1L,PURG,PMP2,RC3H2,DRAM2,MINDY2,CRLS1,CEP41,RAB39A,PRKCG,EPDR1,MAPK10,GDPD1,RELN,CNNM2,SAMD9,BCAS3,SYTL2,SIDT1,GON4L,UHRF1BP1,SPDL1,OCIAD1,ZSCAN2,CEP97,SLC25A48,ACSS3,RASGRF1,RASGRF2,FEZF2,DPF2,FIGN,RFX5,ARHGEF10L,PBRM1,RNASEL,CCDC82,GSTCD,CYB561D1,ELP2,MRAP2,SNX22,NEK11,PRR5L,FAM161B,HSD11B1L,ASIC4,SFPQ,HSPA4L,KIF21A,PPM1E,KIF16B,HKDC1,CHD9,BCAN,PEX26,EPN2,DHX30,RUFY2,LRRC55,SLC12A2,ELMO2,ATF7IP,SLIT1,NAXD,ZNF667,SMARCA4,ANKRD36,LIMCH1,MBD5,SOX5,FNBP1,NMNAT2,CLUAP1,SPP1,KDM4C,KIF1B,TAB2,DIP2A,STXBP1,GSE1,SYT11,SUPT5H,SYNE2,C3orf70,EXOC7,CAMSAP2,FAM208A,UNC5D,VWA3A,TCF4,ZFP90,ZEB1,TPCN2,WASHC4,SYNE1,PCDHB15,RALYL,PCDHB7,AKNA,GPRIN3,RNF216P1,ATP13A2,CRB1,AP4E1,TMEM9,TLL2,BHLHB9,LRRC8A,KCTD2,CSMD1,ZNF384,RGMB,SYNPO2,ELP5,STXBP4,RUSC1,TMPRSS5,HIRA,UBE3A,PLEKHH2,BEST1,NSD2,SLC13A3,ZNF23,KCNT2,PLPP4,LYPD6,ZBTB16,SMARCAD1,PRDM2,LRP8,TMEM178A,HPS4,PCDH15,MPPE1,MVB12B,FAM13C,DOCK8,KAT6A,FBXO36,NUP214,ADAMTSL3,NLRP3,SSPN,IFT88,SOCS4,SLC4A10,SPATA13" MicroRNA hsa-miR-220b:mirSVR_lowEffct hsa-miR-220b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.48E-134 8.28E-131 2.04E-133 1.88E-132 393 1853 "DPF1,SDE2,ABCF1,AS3MT,METAP1D,GPRIN1,PLEKHH1,ADORA1,KIAA1211,OLMALINC,TBC1D14,SEMA6A,ALCAM,PCDH10,ANK3,APBA2,KCNAB2,FAM131A,CPNE5,MIER1,CAPRIN2,PCDHGB4,SLC4A4,ATP2B1,ATP2B2,SLC2A11,CADM3,N4BP2L1,NOL4,BCL2L2,BCL7A,NRP2,GPR146,WASF1,BAIAP3,CACNA1B,CACNB2,CAMK2G,TRIM41,VXN,CH25H,BRSK2,RHBDL1,ARHGEF25,CCKBR,SYNGR3,C1orf52,CDC42,CDH2,DCLK1,LRRFIP1,MS4A7,CPNE6,NMT2,CLTA,FBXO7,IGLON5,ARMC8,SUMF2,AKAP5,SLC4A8,COX4I1,SMARCAL1,MFSD4A,SH2B1,SLC32A1,ANKRD44,NCOR2,GDA,ABCG1,SNCAIP,ARHGEF10,CSNK1E,DZIP3,SDC3,KIAA0040,ERC2,GREB1,RUBCN,NOS1AP,HDAC9,FGFR1OP2,KATNAL2,DCAF8,KIAA0513,TMEM170A,IP6K1,GIT2,ZEB2,HEPH,KLHL3,GUCD1,PLPPR4,SPOCK3,SRGAP3,SGSM2,DLX1,EXOG,DNM1,HS3ST2,DOCK2,DPH1,DRD1,ACOT8,DRP2,DTNB,TOM1,ABCC5,EBF1,SNX29,EDN1,PHC2,SGK2,PHF20L1,IRAK4,TENM1,EPB41L2,ANKRD13B,ZNF549,MRPL37,ANKMY1,MRVI1,CACNG3,ACSL4,TAOK3,FCGRT,FER,FGF1,FGF12,FGFR1,PRKAG2,IP6K2,RGPD5,FOXO3,EVL,NOP56,NSG2,ST6GALNAC3,NSG1,DLL3,B3GAT1,SARAF,TVP23A,ZMAT1,GABBR1,GAD1,GAD2,HBS1L,AHCYL1,GHDC,DISC1,ACSS1,CPLX2,KIAA1841,GCNT2,SULT1C4,GGT7,GK,RND1,TXNL4A,GLI2,MSL3,ZNF638,LILRB4,DIPK1C,NUDT21,TMEM121B,GRIN2C,GRM1,PRDM5,GSTM5,KAT7,LINC01551,TMEM179,HLF,VSIG4,ZNF491,TLX1,MSL1,FAM95B1,IDH3B,ZNF181,RBPJ,USP54,HES5,LRRTM3,NME9,ITGAM,ITPKB,JAK2,KCNJ9,HECTD2,MAPT,MATN2,SYT9,MDM4,SCAMP5,XRRA1,MOBP,GIT1,BLOC1S2,PTOV1,MTTP,MXI1,PABPC1L2A,NDUFA5,NEUROD1,PCBP3,SLC11A2,NTRK2,NTRK3,SETD4,OPCML,OPHN1,LOC100128398,ZNF713,OXTR,ZDHHC22,PCDHGC3,PDGFRA,PFKFB2,ZDHHC8,TMEM38A,ST8SIA5,ZNF426,ANKRD16,CDIP1,RC3H2,LRP12,MAGEL2,ING3,TNPO2,FA2H,PCDHB17P,PPP2R2C,LRRN3,PPP3CA,PPP3CB,MAPK4,HYDIN,SAMD9,VPS13C,SIDT1,PIGG,CNTLN,UHRF1BP1,PTPRG,PTPRH,C1orf109,ATG16L1,SLC25A41,NWD1,ZNF493,OXR1,GTDC1,PBRM1,CYB561D1,ROBO1,ROBO2,PCMTD2,TMEM100,SGSM1,ABCA11P,SOX8,TMEM156,MIR124-2HG,HOGA1,SCN8A,FNIP1,ASIC4,GALNT10,SCAF8,ITSN1,FERMT1,NLGN1,DZIP1,ZNF365,SLC1A6,URGCP,SLC2A5,EPN2,ARHGEF40,CCDC88A,NAPB,BTBD7,LGI3,ZNF667,SMARCA4,MAST1,CDK5RAP2,RCOR3,IFT122,IGSF9B,ANKRD36,INAVA,SNRPN,UNC80,KDM4B,FAM219A,SON,PDZD2,WDTC1,ZSWIM8,UHRF1BP1L,IDI2-AS1,KIF1B,ZBTB43,RBM26,LHPP,CAMTA2,LARP4,SS18,ERBIN,MAPK8IP3,DIP2A,ADHFE1,AJAP1,FGD4,ZFR2,SYNE2,KAZN,EXOC7,FAM208A,UNC5D,VWA3A,ACSL6,TCF7,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,C18orf54,ITGB3BP,CDH22,ARL10,DAAM2,PRMT8,NEIL2,TRPM2,LRTM2,HEPACAM,RPL7L1,PITPNB,PLEKHH2,BCL2L13,MGAT5B,MEAF6,CCDC14,BEST1,WIPF1,PORCN,LGI4,ZIC1,AGMO,ZNF74,LYPD6,TMEM237,AMZ1,ZFAND5,LINC02210,PRDM10,HPS4,SIGLEC10,URM1,LINC00632,AMN1,FZD3,TMEM63C,ZNF248,VANGL2,PIANP,FXR1,LAS1L" MicroRNA hsa-miR-1262:mirSVR_lowEffct hsa-miR-1262:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-134 8.59E-131 2.11E-133 1.94E-132 355 1523 "ABAT,ASIC2,CLK4,AS3MT,CSMD2,CSMD3,ADCY2,DSCAML1,RNF157,ADD1,KIAA1211,SLC44A5,GPR158,SNX32,WDR35,FAM135A,MRTFA,ZFAT,ANK3,C6orf89,CCDC146,SFMBT2,PRX,NUMB,ATP2B3,SLC2A11,LINC00847,RGS9,DCAF5,NRP2,CDK5R1,DST,SYNJ1,MTMR3,NIPA1,BAIAP3,CACNA1B,CACNA1D,CALB1,KALRN,VSTM2A,USP2,P2RX6,LOC730101,MAGI1,NUMBL,SRSF11,ASIC3,CASC2,NDST3,LHX2,KMT2C,SULT4A1,NIPBL,AKAP6,COL11A2,SMARCAL1,CHD1L,CRY2,ABCG1,SNCAIP,OSBPL3,ATRNL1,PDE4DIP,FAM169A,RIMS2,RUBCN,BOC,ARHGAP32,GAPVD1,HDAC4,TOX,ZNF337,CTIF,DCC,ZEB2,PLEKHM1,B3GAT3,MAGI2,TMEM130,POM121,WDR20,DMD,MED12,DMTF1,DPH1,DPYSL2,DRP2,TOM1,USH1C,ABI2,EIF5,C8orf37,EPHA5,RABEPK,ERBB2,ERBB4,ZNF549,ETV1,VPS26C,CEND1,EYA1,CLVS1,ABCA8,ZIC4,CORO2B,RACK1,FKTN,PPP1R1B,OLFM1,FGFR3,POLK,FLT1,FOLR2,NBEA,UFM1,CAMKK2,KHDRBS3,CELF1,DLL3,PNMA2,B3GAT1,HHIPL1,TMEM151A,TBR1,TVP23A,OGA,FYB1,MEGF11,GALNT15,B4GALNT1,ZNF274,GHDC,ATP8A2,GCK,GGT7,C1QL1,DHRS4,TTBK1,RNPS1,RAB30,GPD1,GPM6B,MCHR1,GRIA1,GRIK2,SPACA9,SERP2,GRIN2D,CLASRP,RNF165,FAM107A,GUCY1B1,ATOH8,HPS5,MAN1B1,LINC01102,HLF,HMGCL,HNRNPK,HTR2A,ZNF181,LRRC25,KIAA1755,TJAP1,USP54,SCIN,LIX1,SLC35G1,KCNC1,KCNH2,KCNK1,KIF5A,KIT,IPO5,KTN1,STMN1,MBD1,LDLRAD3,MDM4,MITF,MOBP,CPNE9,BLOC1S2,N6AMT1,MYO9A,NEXMIF,NEUROD2,NF1,VWA2,CNOT4,NRCAM,NRGN,NTRK2,NUCB2,ZNF827,DPY19L2P2,PCSK5,CDK18,PDE3B,ENPP2,CDK14,DUSP26,GDAP1L1,CAMKV,FAM216A,ST8SIA5,PLP1,TRHDE,PRRX1,SDK2,RETREG2,EPB41L4B,FAT3,MINDY2,PPP1R1A,CRLS1,PPP3CB,KANSL1,PRKACB,PRKCG,HYDIN,MASP1,SLC22A23,GON4L,TMEM104,PTCH1,PTHLH,PXK,PTN,PTPRD,PTPRE,PTPRN,PTPRZ1,RIPOR1,ZSCAN2,NKAIN1,RAB3IL1,FAM66C,NWD1,ZCWPW1,RADX,BSDC1,MSANTD2,RFX5,RGR,RGS12,RNH1,ARMC5,CARF,ROBO2,TMEM100,NEK11,RPL15,ZNF671,TCP11L1,STK32B,RPS20,SYNDIG1,HSD11B1L,KCNIP3,HOGA1,LRRTM4,HES6,SMPD3,ASIC4,TRIM46,STUM,FOXRED1,ITSN1,DZIP1,EPN2,DHX30,KANSL3,SLC6A7,RAB3GAP1,SLC20A2,SLCO1A2,SORCS3,ANKRD36,RIMS1,SNRPN,TMCC1,FAM126B,MYT1L,KIF21B,EMC1,TEX2,MCF2L2,DDN,LMO3,TAB2,CLSTN2,ZNF302,SSTR1,MAPK8IP3,ADHFE1,KLHL7,SYT11,ZC3H4,PRRC2C,ARC,TACC1,ANKRD12,KAZN,TAL1,PDLIM2,ALG1,VWA3A,EHBP1,DMXL2,ZEB1,AZIN2,PHF24,OBSL1,AHCYL2,SIK3,PMS2CL,AP4E1,HHIP,TNFRSF1B,R3HDM1,KAT6B,TPD52L2,ZMYND8,PPIL6,TTTY15,UBE2H,CLEC2L,GORASP1,MGAT5B,PLPPR2,CCDC136,LAT2,PCDH20,ZIC1,ZNF28,EML6,PLPPR5,SYNC,PRDM2,EVI5,PARP6,STOX2,LMAN2L,PCDH15,TMEM163,PARP11,DOCK8,UBE3B,PHTF2,CASC15,NUP214,CERS6,FAM219B" MicroRNA hsa-miR-628-3p:mirSVR_lowEffct hsa-miR-628-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-134 9.35E-131 2.29E-133 2.11E-132 354 1515 "ABAT,SYN3,ACADM,CLK4,NCKAP5,FMNL2,CCDC85A,TMCC3,PWWP2A,ZNF608,PCDH19,AK2,HFM1,LRRC7,SPOP,BCAR3,ARHGAP20,AMPD3,ZFAT,OGT,ANK3,SEMA7A,MAP4K3,PKP4,APAF1,GAS7,UPRT,ALS2,USP37,AQP4,PPP4R4,TMEM263,ARRB2,ASPH,ZBTB10,DDX3Y,CCDC181,ATP2B1,ATP2B2,ADGRB3,BCL2L2,NRP2,CFLAR,ARHGEF7,MTMR2,JAZF1,SGCE,CACNA1I,CA12,THSD7A,KALRN,SYT6,CCNH,CIART,SRSF11,CHGB,B4GALT6,NDST3,NRXN3,NRXN1,TPP1,C4orf33,MAP4K4,CNTN1,AKAP6,COL4A5,AKAP5,SLC4A8,ABI3BP,BAG4,MYRIP,NRG2,SLC35F1,CRMP1,GDA,SNCAIP,VCAN,PHF14,GREB1,ST18,EDRF1,DCAF8,PHF19,DNAL1,PITPNC1,C8orf34,MYEF2,CEP170,BLOC1S6,FAM107B,DLG2,EXOG,RAB39B,CPEB2,PDCD6IP,ECM2,DNM1L,FAM135B,ATL1,TMTC1,OPTN,PHF20L1,MBNL2,KMT5B,GOLGA7,KCTD3,PLEKHA1,ELAVL4,RGS17,PAN3,USPL1,LRRC17,KCNMB2,STX2,MRPL10,MRVI1,CLVS1,FABP7,ACSL4,SCML2,MED12L,OLFM1,FOXG1,SLC37A3,NOP56,EFCAB2,NBEA,TACC2,TMEM107,APOPT1,UFM1,ST6GALNAC3,GABRA3,GABRG2,ILDR2,GAD2,B4GALNT1,ARPP21,SALL3,DISC1,GART,MSTN,PCDH17,GLS,LOXL3,LNX1,LILRA1,EML4,GRIA1,GRIA4,GRIK2,LINC00839,GSTM5,RNFT2,MAEL,HLF,HMGB1,SYNPO,HMGCR,HNMT,EID2B,MSL1,TJAP1,SCIN,INSM1,ZNF385B,KCNA2,OLFM3,KCNA4,KCNJ3,KCNK1,GATD1,IPO5,VWA5A,GPR155,MARK3,MATN2,TM6SF1,LRP1B,MID1,POC1B,MMP16,MPP2,SESN3,MSR1,THYN1,MYCN,NEXMIF,NCF2,NEUROD1,NF1,VWA2,NOVA2,SLC11A2,SMIM11A,NTRK2,GPR88,OGG1,OPHN1,GPR137C,PAH,TREM2,PCSK2,BEST3,ANLN,ZFYVE21,GPSM2,FAM216A,PLCL1,PCDH18,PRIMPOL,RC3H2,LRP12,ING3,NXPH1,TATDN3,PPP2R2B,RANBP3L,PRKAB2,PKIA,MASP1,LRRC49,PTN,TMEM260,PTPN13,PTPRZ1,TMEM255A,SH3TC2,ARID4A,RADX,VEPH1,GAL3ST4,ERI2,TTLL7,SLC25A36,RIC8B,CCDC82,GSTCD,TMEM206,ELP2,RPE65,EPHA10,RPL15,ARMH4,LRRK2,LGR4,SAFB,SALL1,SATB1,ATXN2,LRFN5,HOGA1,SCN2A,FAM19A1,SCP2,FNIP1,HES6,TNFRSF19,SOX6,GALNT10,KIF21A,SH3GL3,FRMPD1,KIF16B,FBXO11,FHOD3,CNKSR2,SYBU,SLC1A7,SLC6A1,LRRC55,NAPB,TMEM132D,SLCO1A2,SORCS3,RCOR3,RIMS1,SNRPN,FAM126B,MYO16,SCN3B,MYT1L,TNIK,NMNAT2,HECW1,UHRF1BP1L,KDM4C,TAB2,ITPRID2,CEP68,ADHFE1,AJAP1,VAMP1,ARHGEF9,ADAMTS17,DNAJC9,C3orf70,COBL,C12orf76,ADGRL3,VWC2,TCF7L2,TCF12,SYNE1,DOCK9,PCDHB9,PCDHB4,ARHGEF12,FRYL,ZFPM2,CRB1,C18orf54,ITGB3BP,TGFBR3,TJP1,RIMBP2,RBFOX2,TPM2,TRPC3,TRPS1,TMEFF2,PITPNB,FLRT2,VGF,TBC1D15,RICTOR,KCNT2,TRIM9,FMN2,ZNF138,ZBTB38,POLR3H,ZNF195,PLPPR5,SYNC,EMSY,PRDM2,EVI5,LINC02210,STOX2,RNF103,PCDH15,FAM47E,SLC17A6,UBE3B,PHTF2,CAMK1G,ACTR3B,FAM219B,JMJD1C,MSRB3,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-1911*:mirSVR_lowEffct hsa-miR-1911*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.97E-134 1.11E-130 2.71E-133 2.49E-132 357 1541 "RALGAPA1,DGCR6,CLK4,C3orf14,METAP1D,TMEM132B,ADCY6,ADD1,ADD2,BRAP,KIAA1211,BEND6,SNX32,KIAA1324,SEMA6A,USP35,CARNS1,AMPD2,CDC42BPA,PHF12,SUGT1P4-STRA6LP-CCDC180,APBB2,ALS2,PPFIA3,SHTN1,SHROOM2,ASCL1,PDE8B,PCDHGB4,ZBTB10,NCOA1,NUMB,ATM,MTMR9,N4BP2L1,DPY19L3,DOCK11,TTLL9,ADAM15,MPDZ,RGS9,CFLAR,FUBP1,RAB29,MYRF,CACNA1B,DDR1,TRIM41,VXN,PRC1,CERS5,RGN,CBFA2T2,ENTPD6,ARHGEF2,REPS2,CDH10,L3MBTL4,MAGI1,SRSF11,CASC2,NMT2,TJP2,SULT4A1,SRP14-AS1,COL9A1,BTF3L4,AKAP5,IFFO1,ZFP28,IGDCC3,MFSD4A,CHD1L,ZNF385A,CRY2,ANKRD44,TRIM69,CS,SEC24C,FEZ1,MICAL2,CMTM5,UBXN2A,CTH,PUM1,RIMS2,PPP6R2,ECE2,GAPVD1,RIPOR2,DCAF8,FRMPD4,TOX,IP6K1,C8orf34,KIAA0753,RUSC2,C2CD2L,DDX46,RHOBTB1,SGSM2,GRIN3A,DNM1,SLC29A4,DMTF1,DPP6,ECM2,DNM1L,FAM135B,CNNM1,HEYL,EFNB3,ASB3,EIF4G2,EPB41L1,LRRC17,ENPP6,ANKRD13B,TMEM74,ETV1,EYA1,WAC,PTK2B,TUBB4A,ATP8A1,FCGRT,FGF11,FGFR1,IP6K2,FOXM1,ATP13A4,FLT1,TMEM175,SORBS1,SMC2,HVCN1,TPK1,ZNF605,GABRB1,GALNT15,GABRG2,JPH4,SIGLEC8,INPP5K,WASF3,KIAA1841,ALDH1L1,GCNT2,GPR162,GGTA1P,PPARGC1A,BRD8,SPIN1,GLI2,DCLK2,GNG4,GPR17,GPER1,GRIA4,GRID1,SPACA9,ADAMTS13,GRM1,GRM7,CLASRP,RNFT2,ATOH8,TMEM179,GYG1,FAM222A,MUM1,RASSF8,PADI2,HLF,HNMT,ZNF491,OPALIN,TCEAL6,EID2B,IDH3A,IDH3B,IGSF1,IL6R,IL11RA,LRRTM3,METTL21A,GPR62,KCNJ10,KCNMA1,NCOA7,MBD1,LDLRAD3,LRP1B,KITLG,AFF1,MOBP,MOG,MPP2,MSR1,N6AMT1,NEXMIF,ALDH1L2,NOS1,CNOT4,PCBP3,NTRK3,ODF2,CLDN11,P2RX7,GLIPR1L2,PALM,ETFRF1,PCDHGC3,PCSK1,PDE3B,PDE4D,ZDHHC8,NALCN,SLC25A23,C11orf49,ANKRD16,PDZRN4,CDIP1,STRN3,ING3,SEPT4,TNPO2,FSD1,PPARA,CRLS1,PPP3CB,KANSL1,PRKACB,CEP41,PRKCB,PRODH,GON4L,PTPRE,CASTOR1,PTPRH,PID1,ACSS3,RAD52,FAM66C,NWD1,DBX2,HKR1,KHDRBS2,BSDC1,ZMAT4,ERI2,UBR7,ARMC5,ROBO1,BAALC,LGR4,ST6GALNAC6,DGLUCY,FOXRED2,ATXN7,LRRTM4,CASC3,GALNT10,MRAS,SUPT20H,TRA2B,COPZ1,SGK1,SH3GL2,KIF16B,ASAP3,AMBRA1,ST3GAL3,CTXN2,WDR37,PEX26,PPP4R3A,FAM214B,LRRC55,SEPHS1,SCMH1,LGI3,SMARCA4,IFT122,MAPKBP1,MBD5,KIF13A,KDM4B,USP33,IZUMO4,PEG10,IQSEC2,TSPYL2,SSTR1,MAPK8IP3,SEPT8,RGL1,ADHFE1,KANK1,SUPT5H,VPS13A,SYN2,C12orf76,TACR1,ANKRD12,PJA1,DDHD2,TAL1,UNC5D,ALG1,ADGRL3,TBX15,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PHF24,PUM2,HIF3A,RNF216P1,TF,ZFPM2,LEFTY2,TGFBR3,PIK3R5,ZNF346,TRIO,AMACR,HEPACAM,UBE2H,BCL2L13,ATP6V0E2,GPR158-AS1,NDRG4,SLC26A10,SPIRE1,ZFAND5,PRDM2,RNF103,ADAMTS9,TRIM16L,GJC2,CASC15,FRMD6,SOCS4,SLC4A10" MicroRNA hsa-miR-3164:mirSVR_lowEffct hsa-miR-3164:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.06E-134 2.28E-130 5.56E-133 5.12E-132 366 1621 "SERPINA3,KCNH8,SYS1,ACTN2,CSMD2,ADCY6,ADD1,ADD3,PNMA8B,ERMN,PLEKHH1,PWWP2A,KIDINS220,NLGN4X,INTS2,MTUS1,HACE1,TBC1D14,ALAD,SPARCL1,ALCAM,BBOX1,FAM135A,PDZD4,SUGT1P4-STRA6LP-CCDC180,EPB41L5,VAT1L,USP37,SHROOM2,CASK,ZSCAN18,ZBTB10,ATM,RNF182,ADGRB3,BBS2,MIR9-3HG,BID,OSGIN2,RAB29,MYRF,CFAP410,CACNA1D,CACNB4,KALRN,CAST,KYAT1,SLC16A4,P2RX6,CBFA2T2,REPS2,LARGE1,DLGAP1,IGFN1,CACNA2D2,B4GALT6,KMT2C,TPP1,FBXO7,CNN3,AKAP7,PCYT1B,ARMC8,COL4A5,ABI3BP,IFFO1,RBM39,CSNK1G3,IPCEF1,NCAN,VAC14-AS1,CNTNAP2,DZIP3,PHF14,GAPVD1,DCAF8,TOX,ZNF337,KIAA0586,AIF1L,ARMCX2,ZEB2,MFAP3L,C2CD2L,MAGI2,KLHL3,RHOBTB1,SV2B,AK5,CHRDL1,DMD,USP3,DOCK2,DMTF1,DPYSL2,ATN1,ARRDC4,MAMLD1,EDN1,EDNRA,ANKRD46,CNNM1,PHF20L1,KMT5B,EIF4G2,EIF5,VPS13B,EPB41L1,LRRC17,MTSS1L,EPHA5,ANKRD13B,TMEM74,TUBA1B,PRAM1,ATP8A1,CHST15,PPP1R1B,ZNF589,CAMSAP1,FOXG1,FOXF2,SYNCRIP,EVL,FLT1,NPTN,STAU2,OGA,GABRA1,CHL1,GABRB1,ILDR2,FAM120B,GAP43,DISC1,SRRM4,GATM,GBX2,GCNT2,PCDH17,GLUL,PCDH11X,WDFY3-AS2,LILRB4,PRUNE2,GPM6A,STON1,GPR22,GRIA2,GRID1,GRM3,LINC00839,CLASRP,ZBTB49,RABL2A,PSIP1,RNFT2,IRAK3,ARHGAP19,HMGCL,AGBL5,IGFBPL1,OPALIN,AGFG1,MYLK2,IGF1,C5orf24,DOCK7,TJAP1,IGSF1,ITGAM,ITGAV,KCNA1,KCNC2,KCNJ16,KCNK2,A1BG-AS1,CYP27C1,LIFR,LIG4,SFXN5,LIMS1,NCOA7,MAP2,MARK1,MBP,SYT9,ADAM11,CHIC1,LRP1B,MGAT3,MIA2,MID1,PPM1L,CD200,ERICH3,COL28A1,CCDC80,JAKMIP3,BCO1,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,HNRNPM,NDUFA5,NEUROD1,NFIA,NFIX,NODAL,DNHD1,NRDC,OPHN1,P2RX7,P2RY1,PAH,CNTN3,PBX1,ETFRF1,PCSK2,PDE1A,PDE4D,CCSER2,XRN1,GPSM2,FTO,HMGCLL1,MAPKAP1,SCHIP1,ING3,POLR2F,DRAM2,PPM1B,PPP2R2C,KANSL1,PPP5C,PRKCB,SLC26A11,DIRAS2,SYTL2,GON4L,WDR25,ELOVL2,PTPRB,PTPRE,FAM120C,TTC13,STRC,TMEM231,ACSS3,FAM66C,RASGRF2,RBBP6,RET,RIC8B,SETD5,CARF,PNMA8A,CYB561D1,ROBO1,CCDC102B,TMEM100,BAALC,ZNF671,GLDN,ACER3,WLS,CLIP1,RXRG,ZNF331,SEMA6D,ATXN2,HOGA1,PRCD,SMPD3,ZNF821,ITSN1,PPP1R9A,CHD9,DZIP1,ANKRD6,ARHGEF40,SLN,GKAP1,CDK5RAP2,SMARCE1,LIMCH1,RIMS1,MBD5,ANKFN1,ZNF415,KDM4B,DOP1A,TRERF1,KIF21B,SP4,KIF1B,RBM26,ZNF621,ATP10B,CLASP2,CLSTN2,SMOC1,LRRC4,KANK1,STXBP1,FAM168A,NECAB1,ARHGEF9,COBL,SYT4,ATP11A,TACC1,DDHD2,TAL1,FAM208A,SIN3B,ZFP90,TCF7L2,TPCN2,WASHC4,RALYL,OBSL1,SIK3,AP4E1,HHIP,CDH22,TLL2,NR2E1,TMOD1,KAT6B,C9orf85,TRIO,AMACR,SSBP2,CADM1,LINC00689,WIPF1,GUSBP1,SLC13A3,KCNT2,TRIM9,LYPD6,FSTL5,ZSCAN26,SPIRE1,PLPPR5,ZFAND5,ZXDA,LINC02210,STMN4,FIP1L1,WIPF2,MPPE1,PDSS2,GOPC,DNAH10,MRPL47,DOCK8,FAM219B,TIGD6,VANGL2,SSPN,CBLN2,SLC4A10" MicroRNA hsa-miR-193b*:mirSVR_lowEffct hsa-miR-193b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.49E-134 2.52E-130 6.14E-133 5.65E-132 389 1823 "TTYH1,EMILIN3,METAP1D,ADARB2,ADCY2,ADD2,ESYT2,SLC44A5,KLHL13,RTL9,OSBPL1A,ALCAM,LTBP4,DOC2A,ANK2,USP28,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,APP,SHTN1,AQP4,AQP6,PPP4R4,ZFYVE28,CDK13,ASCL1,MARK4,DACT3,NUMB,EIF4G3,STX16,SLC2A11,RNF182,ALDH7A1,ADGRB1,SNAI3-AS1,ADGRB3,BCHE,RGS11,BCL2L2,NRP2,KSR1,BMP7,ARHGEF7,BTK,BSN,RAB29,BTRC,CA8,CACNB4,CALM1,KALRN,VXN,CAST,RUNX1T1,AIFM1,LRBA,SEPT7,CDC27,ZBED1,CDC42,LGI1,DIS3L,EPS15L1,KIAA1549L,CLCN4,NRXN2,TPP1,NMT2,DNAJB5,SULT4A1,IGLON5,ARHGEF6,CNR1,CNTN1,COL4A5,SUMF2,LETMD1,SLC4A8,ABI3BP,ENTPD4,SH2B1,AKAP12,ANKRD44,CLIP3,ABCG1,TENM4,RGS6,ARHGEF10,MICAL2,PDE4DIP,CMTM5,GREB1,NRSN1,GPSM1,DOCK4,KATNAL2,TCAF1,PHF19,CENPL,TBC1D5,MATR3,MAML1,BRINP1,ZBTB24,HEPH,ELMO1,KIAA0753,COPS7A,ZC3H11A,POM121,RHOBTB1,PLPPR4,WDR20,KIF19,ARNT2,CHRDL1,DLG3,GRIN3A,HS3ST4,DMTF1,SLC25A18,ATN1,GNE,DTNB,MAMLD1,DYRK1A,SNX29,FCF1,CNNM1,SIDT2,ELAVL3,STARD3NL,EPHB1,MRPL37,TLR7,RASL12,SIRPB1,ABCA8,WAC,CHST15,GORAB,GTF2IRD2,FGF11,FGF13,CAMSAP1,POLK,UBE2E3,PCYOX1,FLT1,NOP56,FLYWCH1,EFCAB2,SPECC1,PDLIM5,FAM49B,STAMBP,ARFGAP2,ATP2C1,ZNF605,DACH2,ABLIM2,CHL1,GAD2,HBS1L,FAM120B,ZNF234,DISC1,MYOZ2,GCK,GCNT2,SULT1C4,ADAM28,MALT1,ZNF276,SPIN1,GLS,KDM2B,KCNMB4,GNAS,ZNF782,EML4,GRB10,GRIA2,RFFL,GRIN2D,GRM1,GRM7,BVES,LINC01551,RABL2A,RNFT2,ADAMTS6,SLC2A6,ATOH8,MUM1,MAEL,ZHX1,GPR45,ARHGAP19,HMGB1,HNF4G,TLX1,ATCAY,LINC00667,ZNF546,C5orf24,USP54,SCIN,ZNF385B,ITPKB,METTL21A,KCNJ5,GATD1,KIF5A,CYP27C1,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,ARHGAP12,NCOA7,GPR155,MAOB,MBNL1,CHST6,SCAMP5,POC1B,XRRA1,HS6ST3,RTL5,NDUFA5,NF1,NPTX1,NRCAM,NUMA1,OPHN1,PAK3,PDYN,OLA1,CDK14,DUSP26,GPSM2,ANKRD16,PMP2,SPATA6,PACSIN1,TNPO2,POLR2F,CRLS1,PPP3CB,RASGEF1B,MAPK10,SLC26A11,CNNM2,SYTL2,GON4L,PTPRG,FAM120C,ZNF615,PPP2R3C,PID1,CCDC40,PLEKHB2,SH3TC2,RFX4,ZDHHC4,UBR7,RIC8B,CCDC82,ALG9,PNMA8A,ROBO1,ROBO2,SNX22,ATP8B4,SGSM1,PTGR2,MAPK12,SEMA6D,ATXN2,SCN2B,PRCD,ASIC4,ELMOD1,SEC14L1,GALNT10,ITSN1,KIF16B,CHD9,FNDC3A,SEC31A,NUBPL,PEX26,BTBD3,KANSL3,SLC8A3,SIRT2,ATF7IP,SLC22A4,MAST1,CDK5RAP2,SNRPN,SCN3B,SON,WDTC1,SOX1,ZSWIM8,EMC1,HECW1,MYCBP2,ZBTB43,C11orf87,ATP10B,CLASP2,ITPRID2,SSTR2,INKA2,CEP68,STAC2,ADHFE1,KANK1,GSE1,KLHL7,ARHGEF9,C3orf70,ANKRD28,ROBO3,EXOC7,KLHL4,ANO4,VWA3A,TCF4,DMXL2,ZFP90,TRIM2,SZT2,WDR7,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,SIK3,ZFPM2,CRB1,HHIP,FBXL16,TIE1,DDHD1,PRRT1,CDK20,WBP2,CHST5,ZNF346,METTL3,AMACR,TRPC1,PPIL6,SSBP2,SGK3,SLC35A4,FRRS1L,MEAF6,VIPR2,VSNL1,ZIC2,ZIC3,TCEAL7,ZBTB16,ANKS1B,LAMP5,PRDM2,PRDM10,ADAMTS9,SLC17A7,LINC00632,WIPF2,FZD3,HNRNPA3,IFT88,NETO1,ST8SIA2" MicroRNA hsa-miR-508-3p:mirSVR_lowEffct hsa-miR-508-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.70E-134 3.76E-130 9.14E-133 8.42E-132 353 1513 "RALGAPA1,ADCY2,ADD1,AXIN2,KIAA1211,NLGN4X,MTA3,ZNF608,PCDH19,LRRC7,SPARCL1,SEMA6A,BBOX1,AMPD3,C6orf89,APAF1,EPB41L5,GPAM,ALS2,LRRC4C,MIER1,SLC7A14,LINC00173,CDK13,NCOA1,RASL11B,ATM,ATP1A2,ATP1B3,B3GALT2,NOL4,DPY19L3,DOCK11,DCAF5,BMPR1B,DST,FUBP1,SGCE,OSGIN2,KALRN,PTBP2,CAMK2D,CAMK2G,CAST,HIP1R,RUNX1T1,PRC1,MTMR7,CDC42,LGI1,DLGAP2,DLGAP1,CCPG1,SOCS6,CNOT8,CLCN4,ABCG2,CNR1,ARMC8,COL4A5,SLC4A7,CNRIP1,PREPL,CREM,RBM39,CRHBP,HINFP,ABCG1,MROH8,LRIG1,SIPA1L1,NCAN,PLXNA4,DZIP3,UBXN2A,PLCXD3,CTNND2,USP6NL,DOCK4,GAPVD1,TM9SF4,MATR3,KCTD8,PHYHIP,PABPC5,DNAJC6,ZNF804A,C8orf34,ZEB2,MFAP3L,FBXL5,CEP170,WDR20,DLG2,GRIN3A,NR1D2,DOCK2,DSCAM,DTNA,EDNRB,ATL1,SGK2,FCF1,FRY,RBM12,PHF20L1,MBNL2,ABI2,EIF4G2,COPS4,TENM1,EPHA5,GPHN,EYA1,TAOK3,FER,KIAA1109,FGF12,SUCO,SYNCRIP,FLT1,NOP56,AKAP3,STAMBP,NPTN,KHDRBS3,STAG2,GAB1,GABRA2,GABRG2,CAB39,HBS1L,ZMYND11,GALC,GALR1,SALL3,NCKAP1,DISC1,SRRM4,WASF3,GATM,ALDH1L1,TUBGCP4,ARFIP1,MMADHC,FREM1,PPARGC1A,TCERG1,SPIN1,RAB30,PCDH11X,HTATSF1,OS9,DCLK2,GNAS,ADGRA3,GPM6B,DIPK1C,CNTRL,NR3C1,GRM1,GRM7,BVES,PSIP1,RNFT2,WIF1,NCKAP1L,HLF,HMGB1,HNRNPK,AGFG1,TCEAL6,HSF2,MSL1,IGF1,IGFBP1,DOCK7,LRRCC1,IL6ST,LRRTM3,JAK2,KCNJ10,KCNK2,ASPRV1,PACRG,SMAD9,MAN2A2,AQP11,MATN2,MBD1,LRP1B,MEIS1,KCTD6,XRRA1,LAYN,MYO5A,MYO6,MYO9A,NAP1L1,RCOR2,SLCO1C1,NFIA,CNOT4,OCRL,OPHN1,PCDH8,PCDH9,PCSK5,PCSK2,PDYN,PFKFB3,CAMKV,PIK3R1,KCTD15,FAM216A,ING3,PPARA,PPP2R2C,PPP2R5E,KANSL1,PKIA,EPDR1,HYDIN,RELN,VPS13C,BDNF-AS,PTHLH,TMEM260,ZSCAN32,PTPRG,NKAIN1,TUG1,ZNF844,PID1,RAP1GDS1,RASGRF2,RBBP8,VEPH1,RDX,REV3L,RNASEL,ROBO1,ROBO2,EPHA10,RPL15,FBXW7,SPIN3,MAP6D1,LRRK2,ABCA11P,RTN1,ZNF331,CCDC112,SALL1,ATXN2,ATXN7,SEC14L1,MRAS,SUPT20H,HSPA4L,NTNG1,FNDC3A,NLGN1,SEC31A,SEPHS1,RAB3GAP1,SLC8A3,CCDC88A,SMARCE1,KIF13A,CABCOCO1,PDZRN3,PDZD2,SOX5,BDP1,DOK5,SP4,ENKUR,ERC1,KIF1B,MCF2L2,NFASC,TAB2,EPB41L3,LARP4,ZSCAN29,CEP68,DIP2A,KANK1,KLHL7,NECAB1,FGD4,ZC3H4,PRRC2C,VPS13A,PLCB1,DNMBP,WWC1,EHBP1,TCF7L2,TPCN2,TCF12,AZIN2,SIRT1,DICER1-AS1,AKTIP,CSMD1,PIK3R5,RBFOX2,METTL3,NEIL2,TSC1,RFTN2,UBE2H,UBE3A,LINC00689,DNAJC12,FLRT2,MICAL1,VLDLR,WIPF1,NSD2,WRN,PORCN,XPO1,XRCC4,ZIC2,ZNF711,ZNF24,AGMO,ZNF138,CELF4,FSTL5,ZNF184,ANKS1B,PLPPR5,CADM2,PRDM2,SLC38A1,CSDE1,NAV2,WNK3,SLC17A6,DNAH10,FZD3,UBE3B,PAK5,JMJD1C,RNF170,KLHDC1,FXR1,FRMD6,FAM198A" MicroRNA hsa-miR-4252:mirSVR_lowEffct hsa-miR-4252:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.77E-134 3.80E-130 9.20E-133 8.47E-132 393 1861 "ASIC1,CLK4,ABHD6,AS3MT,FMNL2,ADCY2,GALNT13,ADD1,SLC12A5,PWWP2A,KLHL13,KIAA1324,DISP3,ADGRF5,ALCAM,BCAR3,ARHGAP20,DOC2A,FAM131A,TNRC6C,API5,AQP6,PPP4R4,TMEM263,ARNTL,RGS20,CDK13,ASCL1,MARCH3,MARK4,CAPRIN2,DACT3,ASTN1,ATM,ATP1A2,ATP1A3,STX16,ATP2A2,RNF182,ADAM15,PROM1,CASTOR3,CACNA1G,C5,BSN,MMD2,CA12,CACNA1B,LURAP1,CALM1,HAP1,CAMK2A,TRIM41,CANX,SLC25A14,SPAG9,USP2,P2RX6,NEURL1,CDH8,DCLK1,LRRFIP1,CLGN,DIS3L,CHRNA4,DLGAP3,NRXN3,CLU,NMT2,CLTC,DNAJB5,MAP4K4,CNR1,IFFO1,CNRIP1,CPS1,PNKD,NCOR1,SNCAIP,CSF2RA,SEC24C,CSNK1E,SUSD5,ATRNL1,IPCEF1,SOCS5,PDE4DIP,RASGEF1C,ERC2,PHF14,ZSCAN23,USP6NL,ECE2,CCDC144A,ARHGAP32,DCAF8,FRMPD4,TBC1D5,PABPC5,YTHDC1,DNAJC6,B3GAT3,MFAP3L,FBXL5,C2CD2L,MAGI2,KLHL3,RHOBTB1,KBTBD11,DNM1,HS3ST2,ACOT8,DRP2,RCAN1,ABCC5,ABCC9,TMTC1,YAF2,EFNB3,GOLGA7,EIF5,C8orf37,EN2,EPB41L1,RTN3,ADGRV1,PTK2B,TAOK3,FKTN,STRADA,SLC9B2,GTF2IRD2,KIAA1109,FGF1,FGFR1,BAIAP2,TMEM164,IP6K2,FLYWCH1,EFCAB2,POMT1,ATP6V1H,ERGIC3,CELF1,PNMA2,FYN,GABRA1,GALR1,ERAP1,DISC1,WASF3,GCNT2,CRCP,DBF4,ADGRA3,FUT10,STON1,NUDT21,SPACA9,CACFD1,GRM3,GRM7,BTN2A1,GSTM5,BVES,AP4S1,ATOH8,WIF1,UBE2QL1,HPS5,MAN1B1,ARHGAP19,MIER3,HLF,ZNF491,SMAP1,IRF8,IDH3A,TJAP1,DIPK1A,INPP5B,ITGAM,JAK1,OLFM3,KCNC2,KCNJ10,KCNJ11,KCNN1,KLC1,CYP27C1,STMN1,INSYN2,HECTD2,NCOA7,PACRG,ZFYVE27,MAOB,LDLRAD3,EFHB,MDM4,PPM1L,MOBP,CD200,MSI1,MSR1,PTOV1,N6AMT1,SCG3,DDX25,RTL5,ZNF862,HNRNPM,NAP1L3,NCAM1,NELL1,NEK1,NOS1,NPTX1,GPR137C,ZDHHC22,PCSK5,GDAP1L1,CAMKV,TMIE,XRN1,TMEM38A,PLCB2,TRHDE,MAPKAP1,CDIP1,STRN3,PRRX1,SDK2,PILRA,TNPO2,PPARA,MED1,PPP2R5C,PKIA,MAPK8,MAPK10,KLK6,WBP1L,SIDT1,WDR25,PIGG,ANKHD1,STK32A,FAM120C,ZSCAN2,QDPR,RAB5B,RAD17,CCDC40,PLEKHB2,FAM66C,FAT4,NWD1,OXR1,RASGRF1,DBX2,GAL3ST4,ERI2,RGR,RGS4,RGS12,SEC61A2,RIC8B,NUDT11,RNASEL,SETD5,EXD2,GSTCD,ROBO1,ROBO2,RORB,GLDN,TCP11L1,RMI1,SALL1,MAPK12,ATXN2,ATXN7,HOGA1,SEC14L1,COPZ1,ITSN1,FERMT1,FBXO11,SEC31A,ABLIM3,SMTN,LIMS2,PKNOX2,SLC6A8,SLC6A11,RADIL,SLC8A3,ARHGEF40,SLC9A5,TMEM132D,SPHKAP,GKAP1,SORCS3,INAVA,MBD5,SNRPN,PALLD,FAM126B,MYO16,SON,PDZD2,WDTC1,SOX5,KIF21B,SOX11,GLT8D1,UHRF1BP1L,KDM4C,SPTAN1,SRPK2,ATP10B,SMOC1,LRRC4,ZSCAN29,SEPT8,JMJD6,ZFR2,TACR1,ADGRL3,TBX15,ATMIN,ACSL6,DMXL2,ZFP90,TPCN2,WDR7,PCDHB9,SLC19A3,NSD1,AKNA,USP32P1,ARHGAP9,CCDC173,DICER1-AS1,ZNF106,ZFP91,NR2E1,CSMD1,TNNT1,TPD52L2,C9orf85,WBP2,ZMYND8,FNDC5,TSC1,SSBP2,RPRM,RPL7L1,GORASP1,BCL2L13,MTCH1,CCDC136,VLDLR,LAT2,NSD2,RICTOR,XPO1,ZNF708,ZNF28,LYPD6,TMEM198,ZSCAN26,SPIRE1,WNK1,DNALI1,GDPD5,STOX2,RNF103,SIGLEC10,TRIM16L,MPPE1,RGS7BP,DOCK8,UBE3B,KAT6A,NUP214,VANGL2,ZDHHC20,ST8SIA2,GAN,FAM198A,JPH3" MicroRNA hsa-miR-1304:mirSVR_lowEffct hsa-miR-1304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.58E-134 4.26E-130 1.03E-132 9.47E-132 366 1624 "SERPINA3,SYS1,ADCY2,SLITRK1,RNF157,ADD2,SORCS1,ERMN,SNX30,KCTD16,RTL9,HACE1,OSBPL1A,WDR35,CEP126,BCAR3,OGT,EP400,CNIH2,UPRT,DGKD,ZBTB10,ASTN1,ATM,STX16,ATP2B2,ADGRB3,LINC00847,BCL2L2,MIR9-3HG,DST,SYNJ1,GPC2,PTBP2,CAMK2A,CAMK2D,HIP1R,SPAG9,ARHGEF1,CDC42,LRRFIP1,ASIC3,NDST3,NRXN2,TPP1,CLTA,FAM19A5,CNN3,CNR1,IQCK,PCYT1B,SLC25A27,BTF3L4,AHCTF1,HS3ST5,CHD1L,PNKD,CRY2,HINFP,ANKRD44,CS,MROH8,SNCAIP,OSBPL3,PDE4DIP,CST3,PLXNA4,UBXN2A,NRSN1,RUBCN,CYBB,ARHGAP32,LONRF1,TBC1D5,ACY3,MAML1,TOMM20,MAGI2,BLOC1S6,SV2A,SRGAP3,SGSM2,TMCC2,DOCK2,DMTF1,ATN1,RCAN1,DNAJB6,DYRK1A,E2F6,EDNRA,SGK2,OPTN,SH3GLB1,PHF20L1,TMEM132E,RASA4,GOLGA7,SORBS3,TNK2,C3orf18,PLEKHO1,COQ7,GPHN,STX2,NCALD,GMPR2,F5,CLVS1,FCGRT,FDFT1,FER,GTF2IRD2,FGF1,FGF13,FGFR1,HPCAL4,NOP56,SMC2,HVCN1,FAM49B,NSG2,DACH2,CGREF1,KBTBD12,B3GAT1,TPPP3,AP4B1,PHYHIPL,ZMAT1,GABRG2,DENND2A,AHCYL1,ZNF274,ZNF559,GCNT2,CYP46A1,MMADHC,GHR,LYVE1,NTNG2,TTBK1,HPGDS,TDRKH,EML4,GRIK3,ADAMTS13,NR3C1,GRM2,PRDM5,GRM7,KAT7,FAM222A,IRAK3,BACH2,ZDHHC15,OPALIN,HSD17B1,LRRC75A,SMAP1,HTR2A,HTR5A,C2orf72,NKD1,USP54,ZNF678,KCNA1,OLFM3,KCNC2,KCNJ3,KCNK2,KIF5C,KLC1,PAXBP1,ZFYVE27,MAOB,MAT2A,AQP11,LDLRAD3,KITLG,MITF,AFF1,AFDN,CD200,GIT1,DBNL,SESN3,CCDC80,BLOC1S2,ADAM22,ZNF92,CTNNA3,MTR,MXI1,MYCN,P2RY13,NDP,NEK1,NF1,DNHD1,NRCAM,OCRL,OPRL1,PCDH9,PCSK5,CDK18,PDE4A,PDE4D,GPR85,GNG2,BEST3,PFKFB3,SSH1,ANLN,PIK3R1,FAM218A,A2ML1,PURG,PMP2,MAPKAP1,ING3,RETREG2,POU6F1,PPARA,MED1,PTPA,MAPK4,DIRAS2,SAMD9,WBP1L,MDGA2,PSMD13,CNTLN,PTAFR,PTHLH,PEX5,TTC13,QDPR,RAB5B,TMEM255A,PLEKHB2,NWD1,OXR1,DBX2,KHDRBS2,SLC6A15,FIGN,RGS4,ARHGEF10L,SEC61A2,RAVER2,CARF,NEK11,RPL15,LRRK2,PTGR2,ABCA11P,WLS,TRAPPC13,MIR124-2HG,SEMA6D,ATXN7,SCP2,FNIP1,TNFRSF19,ELMOD1,SOX6,GALNT10,SFPQ,SUPT20H,TRA2B,ZFP30,MAGI3,R3HDM2,BCAN,ST3GAL3,SEC31A,SLA,ZNF365,SLC6A7,SLC11A1,SLC12A2,SLC12A4,CPEB4,DMRTC1,MYH15,ANKRD36,MBD5,FAM126B,UNC80,SON,WDTC1,MYCBP2,SPTAN1,IQSEC2,TSPYL2,NPAS3,ATP10B,EPB41L3,NXT2,DIP2A,NSFL1C,ABCC8,NUDT10,TAC3,CAMTA1,MCF2L,TAL1,UNC5D,DMXL2,SYNE1,AKNA,ARHGEF12,AHCYL2,TF,DICER1,DICER1-AS1,ZFPM2,CRB1,ZMAT3,SLC44A1,ARL10,ICAM5,ERCC6L2,KAT6B,TPD52,SMUG1,STXBP4,TRPS1,ZMYND8,PPIL6,TSN,ANKRD20A2,SSBP2,UCHL1,FRRS1L,PITPNB,PLEKHH2,MGAT5B,TBC1D15,CLDND1,RICTOR,GUSBP1,XPO1,ZIC3,ZNF24,PLPP4,MKRN3,LYPD6,ZBTB16,POLR3H,ZNF184,EML6,DPYSL5,SPIRE1,ZNF225,MFF,STOX2,URM1,FIP1L1,WIPF2,EPM2A,UBE3B,GJC2,CAMK1G,IFT88" MicroRNA hsa-miR-1910:mirSVR_lowEffct hsa-miR-1910:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.08E-134 4.54E-130 1.09E-132 1.01E-131 390 1835 "DGCR6,RBM10,CLK4,KDM5D,XKR4,CSMD3,GALNT16,ADCY6,TMCC3,GALNT13,PNMA8B,RNF150,FAHD2CP,SLC44A5,MTUS1,HECW2,RTL9,OSBPL8,CC2D2A,CARNS1,ZNF687,OGT,FGD2,PI16,CNIH2,SUGT1P4-STRA6LP-CCDC180,PKP4,PARG,APBB1,NT5C3B,AMER3,USP37,AQP6,CDC14B,CDK10,SFMBT2,TMEFF1,SPTBN4,ASPH,DDX3Y,ATP2B1,NOL4,ADAM15,ADGRB2,FGF17,CDK5R1,NAE1,HAP1,CAMK2G,CANX,VXN,CH25H,RUNX1T1,ZNF501,SHISA7,CCKBR,P2RX6,ENTPD6,C1orf52,AP4M1,SEPT7,ZBED1,ZMYM4,CDO1,IGFN1,DIS3L,ADGRG1,CHGA,CHM,RAB3C,IGFBP7-AS1,MYL6B,NGEF,QKI,IGLON5,ARHGEF6,CNTN1,WHRN,COL4A5,SLC4A7,SLC4A8,IFFO1,COX4I1,SMARCAL1,ACBD5,MYRIP,ZFP28,SLC35F1,FAM171B,CRMP1,ANKRD44,TRIM69,RGS6,VAC14-AS1,FAM169A,UBXN2A,ARHGEF4,CFAP61,ST18,NOS1AP,HDAC9,RIPOR2,ZNF337,DGKG,SPOCK2,AIF1L,GIT2,ARMCX4,DCC,SPATA2,YTHDC1,MFAP3L,KIAA0319,CEP170,BLOC1S6,ZC3H11A,POM121,SV2A,DLG3,EXOG,DMD,DNAH9,CD99L2,DPP6,ABI1,DRP2,DTNA,TOM1,DYRK1A,FARSB,DNM1L,ABCC9,E2F5,SEZ6L2,EDNRA,EDNRB,SGK2,FEM1B,KLHL5,FRY,RBM12,EFNB3,GPR61,APH1A,MBNL2,AASS,KCTD3,SORBS3,IRAK4,LRRC23,RTN3,HSPA12B,F5,REEP2,FABP7,TBC1D16,PTK2B,TESK2,KAT8,PPP1R1B,FER,CAMSAP1,FHL1,POLK,IP6K2,FLT1,SLC37A3,C2orf88,ZCCHC17,ATP2C1,ERGIC3,CELF1,DACH2,GPR153,ABLIM2,ZNF512,DKK3,GABRA2,GABRG2,FAM184B,JPH4,ARPP21,GALR1,ZNF274,TMEM8B,LRRC37A6P,GCNT2,SESN1,GFAP,ADAM28,GGTA1P,LYVE1,GLDC,GLI2,TOX3,TNRC6A,PCDH11X,STARD3,DCLK2,CCDC184,CECR2,PCLO,RAPGEF4,GRB10,GRIA1,PLCD4,GSTM5,KAT7,LINC01551,PSIP1,SLC2A6,HAS2,FRMD3,TNFAIP8L3,ZDHHC15,TJAP1,KCNA6,KCNJ11,A1BG-AS1,STXBP5,PAXBP1,PIK3AP1,MAN2A2,ZFYVE27,MAPT,MBP,SYT9,TM6SF1,MDM4,MEF2C,KITLG,POC1B,MKLN1,GIT1,BLOC1S2,PTOV1,NINJ2,NOVA1,SLC11A2,NTRK3,NUMA1,IGSF11,OPHN1,PAX6,PBX1,PCSK5,PDE1B,GPR173,PFKFB2,PFKFB4,ZDHHC8,PLCB2,MTRF1L,PMP22,MAPKAP1,SCHIP1,PRRX1,ING3,MBOAT7,PTPA,PPP2R5E,PPP3CA,RASGEF1B,GRAMD1C,RELN,BCAS3,SIDT1,PSMD13,CNTLN,ELOVL2,PTPRE,FAM120C,C1orf109,PEX2,PEX5,RAB5B,RAD17,SH3TC2,NWD1,RAP1GDS1,ENOX1,BSDC1,RET,RFX5,ZDHHC4,UBR7,RGS3,RGS12,ARHGEF10L,ALG9,ARMC5,RAVER2,NEK11,EPHA10,STK32B,PTGR2,RTKN,ZNF331,SCN4B,HES6,TNFRSF19,ASIC4,SOX6,TRIM46,ZNF821,ARX,KIF16B,MAGI3,DZIP1,BTBD3,KANSL3,LRRC55,SLC15A2,TMEM132D,ATF7IP,OGDHL,CDK5RAP2,SMARCD3,MBD5,TMCC1,SCN3B,SOX5,NMNAT2,EMC1,KDM4C,TEX2,PEG10,KIF1B,IQSEC2,CDK19,RBM26,C11orf87,SMOC1,INKA2,STAU1,VPS13A,TACR1,EXOC7,PDLIM2,CNTN2,VWA3A,ACSL6,DMXL2,PSD3,USP32P1,FRYL,CYB561A3,PMS2CL,HHIP,AKTIP,ARL10,HEY2,TPM4,CHST5,ZNF384,PRMT8,ELP5,DCBLD1,TTTY15,UBTF,GORASP1,OSBP2,CCDC14,BEST1,SF1,PCDH20,ZFP37,ZNF45,FMN2,SLC26A10,ZBTB38,ANKS1B,UPF3A,WNK1,EMSY,LRP8,STOX2,SIGLEC10,TMEM163,CAB39L,EPM2A,DOCK8,RTN4,CASC15,JMJD1C,IFT88,NETO1,CBLN2,SLC4A10,FAM181A" MicroRNA hsa-miR-3139:mirSVR_lowEffct hsa-miR-3139:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-133 6.02E-130 1.45E-132 1.33E-131 378 1730 "KCNH8,ASPHD1,NBAT1,NDRG2,ADAR,ADCY2,SLITRK1,ADCY6,CCDC85A,ADD1,ADD2,SORCS1,PTCHD1,AP2A2,ZNF608,MTUS1,GPR158,HECW2,CC2D2A,AK2,ADGRF5,PCDH10,SYT13,KIF6,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,PHYHD1,VAT1L,CDK10,MARCH3,BRINP2,NCOA1,ATM,STX16,N4BP2L1,ADAM15,BACH1,MIR9-3HG,KSR1,SYNJ2,CASTOR3,MTMR2,BTRC,CACNG1,KALRN,NGB,VXN,HIP1R,KYAT1,CCNH,CBFA2T2,CD38,ENTPD6,LRBA,CDH18,MAGI1,FOXN3,CHN1,PLEKHB1,CASC2,SYNPR,JAM2,RAB28,KIAA1549L,CLCN4,DGCR9,FBXO7,QKI,TMEM184B,SRP14-AS1,LY86,FAM149A,WHRN,TOGARAM2,MFSD4A,CREM,SH2B1,CLIP3,AATK,TENM4,ARHGEF10,MICAL2,ATRNL1,GALNT9,PLXNA4,SLITRK5,PITPNM3,SDC3,CMTM5,CTH,ECE2,CCDC144A,NOS1AP,DOCK4,KIAA0513,IST1,ELMSAN1,DGCR5,HEPH,MYEF2,HP1BP3,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DYNC1I1,DPH1,E2F6,FAM135B,PHC2,HIPK3,CACNG7,SH3GLB1,EFNB3,FAM13A,EGR3,RASA4,C3orf18,SEZ6,EPHB1,KCNMB2,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,WAC,PTK2B,TUBB4A,ATP8A1,FCGRT,FKTN,STRADA,FDFT1,ZNF589,MED12L,OLFM1,FGF11,SUCO,UBE2E3,C1orf61,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,USP21,ZNF605,NSG2,CELF1,ZNF512,DKK3,MEGF10,GAA,GAB1,GABBR1,CHL1,ARPP21,GAP43,DISC1,WASF3,GATM,ALDH1L1,SESN1,USP19,KIRREL3,DHRS4,RAB30,TOX3,MSL3,ZNF638,ADGRA3,PRUNE2,GRIA4,GRM1,PRDM5,GRM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,WIF1,MUM1,PTGDR2,HMGCL,AGBL5,HNRNPK,SHISA6,SHISAL1,ZIC5,DOCK7,DISP2,PLD5,DIPK1A,LRRTM3,JAK1,METTL21A,KCNK1,KCNK3,CREG2,KIT,CYP27C1,L1CAM,SFXN5,SYTL4,LSS,LDLRAD3,SCAMP5,MOG,TAGLN3,MYH7,HNRNPM,NCAM1,NEUROD1,NF1,NHLH1,NNAT,VWA2,NOS1,NUCB1,NUCB2,GPR88,CDK18,PDE3B,PDE4A,PDE1B,GNG2,PFKFB2,PFKFB3,OLA1,CDK14,GDAP1L1,PIK3R1,ZFYVE21,XRN1,KCTD15,ST8SIA5,EPN1,MTRF1L,PLXNB1,PURG,PRIMPOL,POLR2F,POU6F1,PPARA,PTPA,PRKAB2,MAPK4,EPDR1,GRAMD1C,MASP1,TMEM104,STK32A,TMEM231,PLEKHB2,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RFX4,RFX5,RGS3,RGS4,RNF220,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,MCMBP,ATP8B4,NCBP3,FAM192A,CSRNP3,ATXN1,PRCD,SCP2,SEC14L1,SOX6,SELL,FOXRED1,SH3GL2,FERMT1,NTNG1,SYBU,ABLIM3,SLC1A7,URGCP,PREX2,SLC6A1,ARHGEF40,ATF7IP,NAXD,GKAP1,SMARCA4,SMARCC2,CDK5RAP2,ANKRD36,SNCB,SNRPN,UNC80,SP4,KDM4C,IDI2-AS1,IQSEC2,CDK19,ZBTB43,RBM26,NPAS3,CLASP2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,SYT11,JMJD6,ZFR2,ARHGEF9,VPS13A,C3orf70,PLCB1,SYN2,POPDC3,TACR1,ANKRD12,ROBO3,DNMBP,VWA3A,TCF4,RPGRIP1L,SYNE1,NSD1,CCDC173,AP4E1,GZF1,ASXL3,FAM124A,TPD52,NPL,CHST5,SMUG1,NEIL2,TRPC3,TRPS1,SSBP2,RFTN2,PRR18,UBTF,DNAJC12,BEST1,CLDND1,ZNF19,ZNF70,SLC26A10,AMZ1,PLPPR5,URM1,WIPF2,UBE3B,NUP214,CERS6,PIANP,FAM198A,JPH3" MicroRNA hsa-miR-421:mirSVR_highEffct hsa-miR-421:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.75E-133 9.83E-130 2.36E-132 2.17E-131 337 1385 "SDE2,CLK4,ACTN2,ADD1,ADD3,RNF150,KLHL13,AGT,WDR35,OSBPL8,AK2,SPOP,SRPX,CEP126,FAM135A,DPP10,PPFIA1,DDO,TNRC6C,SHTN1,MIER1,ARNTL,CCDC74A,ASPH,ZSCAN18,ATM,SLC4A4,B3GALT2,BARD1,SEC11C,NRP2,GPC2,CA8,PTBP2,SLC25A14,RUNX1T1,CLDN10,LDB2,LGI1,CFL2,SRSF11,CHI3L2,CASC2,KMT2C,CLCN3,QKI,NIPBL,CNTN1,ARMC8,AKAP6,LETMD1,SLC4A7,MAGED1,RTTN,BAG4,ZFP28,CPS1,PREPL,ANKRD44,CS,MICAL2,SIPA1L1,PDE4DIP,APPL1,ZFYVE16,ZNF337,LONRF1,MAML1,DGKB,CTIF,JAKMIP2,BLOC1S6,RHOBTB1,SNAP91,SACS,SPOCK3,SV2A,RABGAP1L,FAM107B,DLG2,USP3,DYNC1I1,NR1D2,DPP6,DSCAM,ECM2,DYRK1A,DNM1L,PHC2,HIPK3,FCF1,SYT15,FAM13A,KMT5B,PLXNC1,ELAVL2,RCAN2,EPHA5,STX2,EPS8,CDKL3,DNAJC27,FAM198B,CHST15,TESK2,GORAB,SLC9B2,MED12L,OLFM1,POLR1B,FGF13,FGF14,FHL1,SUCO,UBE2E3,MEX3B,CAP2,IP6K2,SEMA4D,ATP13A4,SLC37A3,COQ5,EFCAB2,TRMO,TMEM107,FAM49B,TPK1,NPTN,ATP6V1H,ATP2C1,MSANTD4,OGA,DKK3,HRASLS5,BRPF3,ZMYND11,ARPP21,NCKAP1,ERAP1,MTHFD2,ZNF559,GART,LRRC37A6P,SRCAP,PCDH17,GPR75,ZNF638,GPD2,PRUNE2,FUT10,GRIA4,GRIK4,NR3C1,GRM8,FAM19A2,AP4S1,ARHGAP19,CFAP126,EID2B,LRRCC1,PLD5,IL6ST,INPP1,KCNJ10,IPO5,ARHGAP12,PACRG,SMAD1,MARK1,SYT9,MEIS2,AFDN,CD200,ADAM22,NRBP2,TAGLN3,MYBPC1,NAP1L1,NCAM1,NEK1,NEUROD1,OTOGL,CNOT4,NRCAM,SMIM11A,CLDN11,PAH,PCMT1,PRTG,PDE4B,PENK,PFKFB3,XRN1,GPSM2,STRN3,RC3H2,EPB41L4B,SH3KBP1,POU3F4,PPM1B,CRLS1,PPP2R5E,KANSL1,GRAMD1C,PRPSAP2,BCAS3,CNTLN,PTK2,PTPRB,PTPRD,PTPRO,PTPRZ1,RAD17,RASGRF2,RDX,ZYG11B,GTDC1,RFX3,RFX4,SEC61A2,NUDT11,RNASEL,CCDC82,CARF,GSTCD,RORB,RPE,MCMBP,ACER3,TCP11L1,LGR4,ABCA11P,RTKN,KCNIP2,SEMA6D,ELMOD1,ITSN1,ARX,HKDC1,MAGI3,ST6GAL1,ANKRD6,PPP4R3A,EPN2,SEPHS1,RAB3GAP1,KBTBD4,SLC12A2,TMEM132D,CPEB4,SORCS3,DMRTC1,SMARCE1,LIMCH1,SNAP25,MBD5,WDTC1,MYT1L,SOX5,BDP1,C11orf87,TROVE2,COLGALT2,SAMSN1,SSTR2,LRRC4,ERBIN,ELOVL4,TTBK2,NSFL1C,SYNE2,ARHGEF9,PLCB1,SYT1,ANKRD28,MMS19,TACC1,ANKRD12,CAMTA1,DNMBP,ADGRL3,FBXW11,KLHL4,TCEA1,DMXL2,CUX2,ZEB1,TRIM2,RALYL,SLC19A3,TEX15,FAM200B,PMS2CL,FBXL16,ARL10,GZF1,TMPO,C5orf64,TP53BP1,CDK20,C9orf85,PRMT8,SMUG1,NEIL2,AMACR,TSN,CA14,ANO5,TTC3,TUBB2A,SGK3,CADM1,CCDC14,VSNL1,NSD2,CLDND1,XRCC4,SF1,ZIC1,ZIC2,MICU3,ZNF540,NDRG4,TCEAL7,FSTL5,SPIRE1,WNK1,CADM2,LINC02210,SCG2,GOPC,FAM13C,ACTR3B,ZNF248,RNF146,SLC4A10,GAN" MicroRNA hsa-miR-218:mirSVR_highEffct hsa-miR-218:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.94E-133 1.09E-129 2.60E-132 2.40E-131 324 1281 "RALGAPA1,ACTN1,CSMD3,ADARB2,ADCY6,GALNT13,SORCS1,BEND6,SLC24A4,NME5,KIAA1324,SYT13,LCORL,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,UPRT,SHTN1,CDK10,RGS20,ASPA,CCDC74A,NUMB,INSYN2B,ZNF583,MTMR9,BACH1,ADGRB3,SEC11C,BCHE,PROM1,CDK5R1,CALM1,KALRN,SLC25A14,VXN,CCNH,INA,TMEM257,CDC27,L3MBTL4,SOCS6,CHM,JAM2,NRXN3,NRXN1,NMT2,TJP2,ABCG2,FHL5,ARMC8,SUMF2,ABI3BP,ZFP28,SLC35F1,FAM171B,PREPL,CRHBP,ANKRD44,TRIM69,CRYM,SNCAIP,RGS6,LRIG1,ATRNL1,ERC2,CTNND2,PUM1,ST18,ZSCAN23,EDRF1,RIPOR2,KCTD8,AIF1L,DBN1,DCC,ZEB2,ELMO1,MAGI2,RHOBTB1,PLPPR4,SACS,SV2B,SPOCK3,SV2A,RABGAP1L,DLG2,HS3ST2,NR1D2,ARRDC4,GOLT1B,EBF1,ATL1,CNNM1,KLHL5,FAM13A,EGFR,MBNL2,KMT5B,GOLGA7,CALCRL,PAN3,OLIG2,LRRC17,EPHA5,GPHN,EPS8,RTN3,MRVI1,NSRP1,FAM198B,ZNF461,KAT8,GORAB,FER,MED12L,FGF12,POLK,SCARA3,FOXF2,FLNC,NELFCD,C2orf88,TMEM107,APOPT1,ZNF605,KHDRBS3,STAU2,B3GAT1,OGA,GABRB3,TRAF3IP2,ERAP1,WASF3,TUBA8,MALT1,LYVE1,COPS8,GLI2,RAB30,TOX3,ZNF638,GNAO1,GNAS,GPM6A,PCLO,GRIA2,GRIA4,GRIK2,GRM1,GRM3,GRM5,ZBTB49,SOX21,GUCY1A2,GPR45,MIER3,HLF,ELOVL5,HMGB1,HNMT,C9orf129,ZDHHC15,SHISA6,IRF8,PLD5,BRINP3,ZNF678,OLFM3,KCNH1,KIF2A,KIT,STMN1,INSYN2,HECTD2,NCOA7,MBNL1,LRP1B,MEF2C,MEIS2,MITF,MOG,ERICH3,MDGA1,MXI1,NELL2,NODAL,GPR88,SNTG1,PCDH8,PCDH9,PDGFRA,PDYN,SERPINI1,PIK3C2A,ANLN,PIK3R1,ST8SIA5,TRHDE,MINDY2,CCDC144B,PPP2R2C,PPP2R5E,KANSL1,CEP41,PKN2,MAPK9,HYDIN,MASP1,RELN,VPS13C,MDGA2,ELOVL2,ZSCAN32,RASGRF2,ARID4A,RNF220,SLC25A36,ZFHX4,TMLHE,GSTCD,ROBO1,ROBO2,PCMTD2,RPE,UEVLD,ATP8B4,LGR4,KCNIP3,ATXN2,SCN2A,SCN2B,SCN8A,SUPT20H,KIF16B,SHC4,FNDC3A,FHOD3,ABLIM3,SLA,FAM81A,PPP4R3A,BTBD3,WDR47,SLC6A1,LRRC55,SLC6A11,SLC8A1,CCDC88A,SHANK2,SLC12A2,SPHKAP,CPEB4,NAXD,SLN,COA1,SORCS3,SMARCE1,IFT122,RIMS1,MYO16,MYT1L,SOX5,KDM4C,LMO3,C11orf87,TAB2,NKAIN2,ERBIN,DIP2A,STXBP1,NECAB1,JMJD6,VPS13A,NUDT10,C3orf70,TMEM150C,SYN2,SYPL1,TAC1,ANO4,SATB2,TCF7,TCF12,WDR7,SYNE1,DOCK9,ARHGEF12,PCDHA5,CHST8,GZF1,ACTR6,TMPO,RIMBP2,TPD52,AMACR,STXBP4,TRPC3,DCBLD1,SGK3,UBE2H,UCHL1,UGT8,RBFOX3,TRIM9,CELF4,SPIRE1,UPF3A,CADM2,DNALI1,CSDE1,GDPD5,RNF103,NAV3,TMEM163,CAB39L,SLC17A6,RTN4,ZNF248,NHSL1,DPF3,GAN" MicroRNA hsa-miR-3146:mirSVR_lowEffct hsa-miR-3146:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-133 1.12E-129 2.68E-132 2.46E-131 326 1297 "ABCF1,CLK4,KDM5D,FMNL2,ADCY6,TMCC3,BRAP,ERMN,PLEKHH1,INTS2,MTUS1,HECW2,HACE1,OSBPL1A,AK2,LRRC7,SPARCL1,SMIM17,ALCAM,SRPX,ANK2,ANK3,EP400,CCDC146,LCORL,MAP4K3,ALS2,BCAS1,TNRC6C,CDK13,ASPH,ATM,SLC4A4,MYOM1,SNAI3-AS1,NRP2,BID,GPC2,WASF1,CA12,CACNA1E,CACNB4,CABP7,CANX,ISPD,MAP7,CBFA2T2,C1orf52,MYOM2,SEPT7,CCPG1,CLGN,FOXN3,CHGB,CASC2,IGFBP7-AS1,NRXN1,TPP1,ARMC8,SUMF2,BTF3L4,SLC4A8,RCHY1,CP,CHD1L,C2CD2,CRHBP,ANKRD44,NCOR1,CLIP3,CRYM,OSBPL3,CSNK1G3,SOCS5,FAM169A,DZIP3,UBXN2A,PHF14,NRSN1,ZSCAN23,TOX,MAML1,TOMM20,BRINP1,ELMSAN1,ZEB2,MYEF2,ELMO1,SPOCK3,TMCC2,DLG2,EXOG,DRD1,EBF1,FSD1L,OPTN,EFNB3,FAM13A,EGR3,KCTD3,EIF4G2,ELAVL2,RGS17,EPHB1,STX2,SRRM1,ANKMY1,MRVI1,NSRP1,CHST15,SEC24B,KIAA1109,FGR,SYNCRIP,FOXO3,PDLIM5,NPTN,CELF1,STAG2,MEGF11,DKK3,GAB1,GABBR1,GABRA1,GABRA2,GABRG1,DENND2A,DNER,GCNT2,GDF9,RNPS1,SPIN1,GLS,MSL3,PCDH11X,LUZP2,TDRKH,STON1,TMEM121B,PCLO,SPACA9,BTN2A1,ZBTB49,PSIP1,WIF1,ARHGAP19,HLF,IRF8,DOCK7,USP54,KCND2,KCNMA1,CREG2,KIF2A,KIF5C,LAMP2,LIFR,PAXBP1,LYPLAL1,MBNL1,CHIC1,TM6SF1,MDM4,LRP1B,AFF1,XRRA1,SESN3,CTNNA3,MX1,LYRM9,MYO5A,MYO7A,PABPC1L2A,NACA,NAP1L1,NAP1L3,NCAM1,NDUFA5,NEK1,CNOT4,NOVA1,HCN1,NTRK2,IGSF11,OPA1,ZNF713,ZDHHC22,GLIPR1L2,PCDH9,PCMT1,PRTG,GPR85,DUSP26,SNX10,ZFYVE21,XRN1,STRN3,MAGEL2,ING3,SPATA6,EPB41L4B,MINDY2,PPP2R5E,PPP3CB,KANSL1,PRKACB,CEP41,SLC26A11,GON4L,MDGA2,QRICH1,PTCH1,TMEM260,ZSCAN32,PTPRB,FAM120C,RAB5B,PID1,ZNF493,FEZF2,RBBP6,KHDRBS2,RDX,REV3L,RGS10,RGS12,SLC25A36,RNASEL,ZFHX4,LGI2,DCUN1D2,TMLHE,ROBO2,PCMTD2,BAALC,PRR5L,LRRK2,KCNIP3,RTN1,CCDC112,TRAPPC13,SATB1,ATXN2,SCN7A,LINC00461,IL17RB,SELL,CASC3,FERMT1,CPEB3,SHC4,HKDC1,ST6GAL1,NLGN1,PPP4R3A,KDM4D,RAB3GAP1,CCDC88A,KBTBD4,SLCO1A2,SLIT1,CPEB4,SMARCE1,RCOR3,LIMCH1,SNAP25,SNRPN,SP4,ENKUR,HECW1,ERC1,CDK19,NPAS3,SPART,EPB41L3,DIP2A,SULF2,KLHL7,FGD4,SYNE2,ARHGEF9,C3orf70,PLCB1,TACR1,AGTPBP1,TMEM136,ACSL6,CUX2,TCF7L2,CLASP1,RALYL,CCDC173,TEX15,FAM200B,DICER1,SIRT1,TJP1,NR2E1,TP53BP2,NPL,RFTN2,HEPACAM,RPL7L1,FAM155A,PITPNB,BCL2L13,CCDC14,PCDH20,ZIC3,TRIM9,FMN2,PLPP4,ZBTB38,FSTL5,RNF103,HPS4,PCDH15,SLC17A6,PLSCR4,DOCK8,ST7,HNRNPA3,FBXO36,ADAMTSL3,SOCS4,ST8SIA2" MicroRNA hsa-miR-591:mirSVR_lowEffct hsa-miR-591:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-133 1.20E-129 2.85E-132 2.63E-131 319 1242 "RALGAPA1,CSMD3,GALNT16,ADD1,PTCHD1,SLC24A4,AP1B1,ZNF608,CASKIN1,SORCS2,WDR35,SRPX,PCDH10,SYT13,LRCH2,ANK2,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,EPB41L5,APOC2,TMEM263,TMEFF1,ARNTL,ATP1A2,ATP2B1,ATP2B2,N4BP2L1,MPDZ,DCAF5,PROM1,SYNJ2,PRMT9,C5,NIPA1,MMD2,CACNA1D,THSD7A,KALRN,PTBP2,SLC25A14,ARHGEF25,SYNGR3,SRSF11,CHM,RAB3C,RAB33A,NRXN3,NMT2,DGCR9,TMEM59L,C4orf33,MAP4K4,AKAP6,SLC25A27,SUMF2,TOGARAM2,ZNF521,ZFP28,ZNF385A,SLC35F1,ANKRD44,CLIP3,CS,SNCAIP,LRIG1,PUM1,RIMS2,FGFR1OP2,PHF19,ZNF337,RASSF2,LONRF1,SPOCK2,ARMCX4,YTHDC1,ZEB2,CEP170,TMEM130,SACS,EXOG,DMD,DYNC1I1,DNM2,ACOT8,ATN1,DTNA,DTNB,GOLT1B,ATL1,HIPK3,FCF1,SEMA3D,EGR3,LPAR6,EIF4G2,PLEKHA1,RGS17,EML1,ENO2,ETV1,SIRPB1,MRVI1,RPS6KC1,RACK1,FCGR3A,FKTN,KAT8,TMEM164,NBEA,TMEM107,SMC2,UFM1,PDLIM5,NPTN,ATP6V1H,STAU2,STAG2,GABBR1,GABRB1,GALNT15,AHCYL1,B4GALNT1,GAP43,INPP5K,GPR162,GK,SPIN1,GLYR1,GLS,LUZP2,FERMT2,PRUNE2,GPR12,CECR2,PCLO,STMN2,GRIA2,GRIA4,PLCD4,GRIN2C,GRM1,AP4S1,SOX21,FRMD3,BACH2,USP51,NEGR1,HSD17B1,LRRC75A,HSP90AA1,HTR5A,ATCAY,MSL1,IDH3B,DOCK7,IL11RA,TUBB2B,KCNC1,KCNN2,TTYH2,LIFR,LIMS1,SYTL4,NCOA7,LSS,ASPRV1,MAOB,MAP2,MATN2,MEIS2,KCTD6,KITLG,MMP16,MN1,MOBP,BLOC1S2,TAGLN3,MTTP,TCEAL5,NAP1L1,P2RY13,NDUFA5,NELL1,NEK1,NELL2,NF1,SLCO1C1,LRIT2,OPA1,PCSK2,PRTG,PDE1B,PDGFRA,SERPINI1,PIK3R1,ZNF655,NLE1,PLCL1,ANKRD16,MAPKAP1,SCHIP1,RETREG2,TNPO2,POU3F2,POU6F1,PPP2R5C,MAPK4,HYDIN,MASP1,SAMD9,LAMA1,SNRK,CNTLN,PLPPR1,TMEM260,ZSCAN32,PTPRB,OCIAD1,EML5,PTPRE,TUG1,PPP2R3C,PID1,FAM66C,SH3TC2,KHDRBS2,BSDC1,ARHGEF10L,RNF220,RIC8B,ROBO2,TCP11L1,WLS,HOGA1,TRIM46,SCAF8,SGK1,ITSN1,SH3GL2,DOCK10,CHD9,FNDC3A,SLITRK3,CNKSR2,CLSTN1,SLA,SLC1A3,URGCP,BTBD3,SLC6A1,SEPHS1,SLC15A2,ATF7IP,CPEB4,NAXD,SLN,GKAP1,SMARCD3,SP4,RBM26,NPAS3,POGZ,SSTR1,INKA2,STXBP1,FGD4,ZFR2,VPS13A,PLCB1,TAC1,KAZN,PJA1,PDLIM2,TBX15,TCF4,TCF7,CLASP1,SYNE1,NSD1,HIF3A,RNF175,SIK3,AP4E1,HEY1,TJP1,SMUG1,TRPC1,FNDC5,TSC1,ANO5,ZKSCAN5,TMEFF2,EIF4ENIF1,UBE2H,AMOT,SLAIN1,PITPNB,MTCH1,WIPF1,WRN,RICTOR,GUSBP1,XRCC4,PCDH20,TRIM9,FMN2,PLPP4,LYPD6,POLR3H,CA10,ADAMTS9,PCDH15,NUP214,ZNF248,TIGD6,MSRB3,PIANP,FRMD6" MicroRNA hsa-miR-4303:mirSVR_lowEffct hsa-miR-4303:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.85E-133 1.60E-129 3.80E-132 3.50E-131 384 1788 "TTYH1,ABCF1,ACHE,CLK4,ADAR,FMNL2,ADCY6,ADD1,ADD2,SLC12A5,ERMN,PTCHD1,KLHL13,CC2D2A,C1QTNF1,C1QTNF3,SEMA6A,AMPD3,CDC42BPA,DPP10,CNTNAP1,APBA2,DGKD,CACHD1,IGDCC4,CASK,LINC00173,ASCL1,NUMB,ALDH4A1,ZNF583,ADAM15,SNAI3-AS1,BARD1,CFLAR,KSR1,BMPR1B,CDK5R1,ARHGEF7,CASTOR3,CACNA1G,WASF1,MYRF,CFAP410,CANX,CBS,CDH2,L3MBTL4,CCPG1,CFL2,CASC2,DGCR9,FBXO7,VAX2,C4orf33,HECTD1,MAP4K4,ARMC8,SMARCAL1,IGDCC3,CHD1L,ANKRD44,GDA,CS,CSF1,OSBPL3,NCAN,PHACTR3,DZIP3,PHF14,CFAP61,CX3CR1,CYBB,TOX,LONRF1,IST1,DGKB,GIT2,MYEF2,CNIH3,RUSC2,CEP170,MAGI2,SGSM2,DLG3,GRIN3A,DMD,HS3ST2,DOCK2,DMTF1,MAMLD1,DYRK1A,DNM1L,ABCC9,WDPCP,EDN3,PHC2,ANKRD46,HIPK3,SYT15,CNNM1,HEYL,KLHL5,EFNA3,EGFR,EGR3,EIF4G2,SORBS3,COPS4,ELAVL4,STARD3NL,EPB41L1,RCAN2,ENPP6,ANKRD13B,STX2,ETV1,MRVI1,DLC1,FCGR1A,TOMM40L,FCGRT,FGF11,AMOTL2,ATP13A4,NELFCD,NBEA,TACC2,SPECC1,APOPT1,USP21,PNMA2,MSANTD4,AP4B1,DOT1L,FYN,MEGF11,DKK3,HRASLS5,TRAF3IP2,HBS1L,SALL3,ACSS1,GPR162,CYP46A1,GGT7,HEPN1,GHR,LYVE1,MSL3,GNG3,LNX1,GPD1,ATF7,STON1,NUDT21,EML4,GRB10,GRIA2,GRM2,ZNF496,LINC01089,PTPRT,ZBTB49,MFSD2A,RASSF8,HAS2,MAN1B1,VSIG4,HMGB1,SYNPO,DHX35,SMAP1,ICA1,FAM95B1,MYLK2,INPP5B,NME9,KCNMA1,KCNN2,KHK,KLC1,IPO5,KTN1,SFXN5,NCOA7,MAP6,LYPLAL1,MAT2A,AQP11,MDM4,MGAT3,MMP16,NCAM2,ZC3H12B,SFR1,NF1,NINJ2,NODAL,SLC11A2,NRCAM,TBC1D25,OPHN1,P2RY1,PAK3,PAX6,PDE3B,PDE4D,PDGFRA,PDYN,GNG2,PENK,HERC2P3,ZNF655,RETREG1,TMEM38A,PLCD1,ANKRD16,PMP22,MAPKAP1,EPB41L4B,FAT3,NXPH1,POU3F2,POU6F1,PPARA,MINDY2,RASGEF1B,PRKACB,PKIA,RAB39A,NDUFS7,SYTL2,DEF8,PSMD13,PTCH1,PXK,PTPRG,ZSCAN2,PPP2R3C,RAB5B,USP47,ACSS3,ATG16L1,RASGRF1,RASGRF2,ARID4A,RBBP6,ZDHHC14,ZMAT4,MORC4,RGS3,PRIMA1,ARHGEF10L,RNASEL,RNH1,CCDC82,ZNF532,CARF,GSTCD,ROBO2,CCDC25,ELP2,RPE65,SNX22,NEK11,RPL15,ARMH4,ZC3H14,MCMBP,ACER3,LRRK2,LGR4,ABCA11P,HSD11B1L,CLIP1,TMEM156,SCN8A,ASIC4,CASC3,MRAS,SUPT20H,KIF27,SH3BGR,ASAP3,DOCK10,NTNG1,NLGN1,ST3GAL3,ANKRD6,PAAF1,ZNF365,URGCP,SLC6A1,LRRC55,SEPHS1,CCDC88A,TET1,SLIT1,NAXD,SORCS3,CDK5RAP2,SMARCE1,SNAP25,MAPKBP1,MBD5,TMCC1,DOP1A,MYT1L,KIF21B,BDP1,HECW1,MYCBP2,CAMTA2,POGZ,COLGALT2,ZC4H2,STAC2,KANK1,SYT11,FGD4,VAMP1,VPS13A,C3orf70,ATP11A,KAZN,ROBO3,TAF6,ADGRL3,KLHL4,MGRN1,VWA3A,SATB2,RPGRIP1L,WASHC4,WDR7,RALYL,TNS2,HIF3A,CYB561A3,RNF216P1,LEFTY2,SLC44A1,TJP1,BHLHB9,ZFP91,HEY2,LRRC8A,TNFRSF1B,R3HDM1,C5orf64,TP53BP2,TRIO,AMACR,RUSC1,KCNE5,SSBP2,CLHC1,UGT8,WIPF1,NSD2,LGI4,KCNT2,ZNF142,AMZ1,SYNC,PMEPA1,STOX2,ADAMTS9,FIP1L1,PDSS2,FZD3,DOCK8,NUP214,CERS6,RNF170,VANGL2,MSRB3,AP3B2,ZNF30,PRRT4,FAM198A,SENP7,JPH3" MicroRNA hsa-miR-374a*:mirSVR_highEffct hsa-miR-374a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.16E-133 1.77E-129 4.20E-132 3.87E-131 355 1537 "KCNH8,CLK4,NBAT1,TKTL1,ARID1A,ADCY8,AXIN2,ERMN,PLEKHH1,BEND6,MTUS1,WDR35,ZNF578,LRRC7,SPARCL1,SEMA6A,ALCAM,ABCD2,ARHGAP20,PCDH10,FAM135A,OGT,DPP10,LRCH2,ANK3,APC,BCAS1,API5,PPP4R4,CDK13,ASPH,ZBTB10,DCAF5,ZNF599,BMP7,DST,NAE1,WASF1,CACNA1B,KALRN,CAMK2D,VSTM2A,LDB2,KRIT1,C1orf52,LRBA,CDC27,CDC42,MAGI1,CFL2,CHM,ZBED5,CNOT8,RAB28,PLAA,NIPBL,CNR1,ARMC8,COL4A5,ABI3BP,ACBD5,ZFP28,SLC35F1,CLOCK,PREPL,CS,SNCAIP,LRIG1,LRRC3B,CSNK1G3,SLITRK5,UBXN2A,CTNND1,HDAC9,ZFYVE16,LIN54,IST1,DAPK1,PABPC5,DCC,JAKMIP2,ZNF804A,C8orf34,ZEB2,MYEF2,LYPD1,DDX46,ALKBH8,PLPPR4,AK5,MTX3,CPEB2,DPP6,DPYSL2,E2F6,EDIL3,EDNRB,SYT15,KLHL5,FSD1L,OPTN,PHF20L1,MBNL2,ABI2,KCTD3,PAN3,EN2,COQ7,RCAN2,EPHA5,EPHB1,KCNMB2,CDKL3,RTN3,RRAGB,ADGRV1,ABCA8,ACSL4,CEP78,FLT1,HVCN1,STAMBP,DACH2,AP4B1,OGA,GABRA2,GABRB1,GABRG2,CAB39,IQGAP2,SULT1C4,FREM1,PPARGC1A,HPGDS,SPIN1,GLRB,TOX3,PCDH11X,ZNF638,MAP7D2,GNAS,LILRB4,NUDT21,PCLO,GRIA1,NR3C1,GRM1,FAM19A2,GUCY1B1,MAEL,HAS2,HPS5,C1orf94,ZHX1,NXPH2,MIER3,VSIG4,HMGCR,HSP90AA1,C5orf24,RBPJ,LRRCC1,PLD5,LIX1,ITGAV,KCNC2,KCND2,KCNJ3,KLHL23,STXBP5,L1CAM,HECTD2,MAP2,MARK1,MATN2,MATN3,MBNL1,MDM4,MEIS1,KCTD6,XRRA1,MMP16,ERICH3,RSPO2,LYRM9,MYO6,NELL2,NF1,SLCO1C1,NOVA1,DNHD1,NRCAM,TBC1D25,GPR88,OGG1,P2RX7,ZDHHC22,PAH,PAX6,PCMT1,PDCD2,PDE3B,PDE4B,PDE4D,PDGFRA,GPR85,NALCN,ZNF655,PCDH18,MTRF1L,ANKRD16,PMP22,SPATA6,EPB41L4B,DRAM2,PPM1B,CRLS1,PPP2R5E,PPP3CB,PKIA,HYDIN,SAMD9,WBP1L,LRRC49,MDGA2,PTHLH,TMEM260,STK32A,ZSCAN32,PTPRG,PTPRO,PPP2R3C,TMEM255A,OXR1,KHDRBS2,ZMAT4,ERI2,GTDC1,TTLL7,RIC8B,DCUN1D2,TMLHE,RAVER2,ELP2,ATP8B4,ACER3,LRRK2,LGR4,RPS20,ATAT1,ZNF354C,TRAPPC13,AMER2,SATB1,SCN3A,SMPD3,ELMOD1,SCAF8,SGK1,NTNG1,NLGN1,SEC31A,DHX30,FAM214B,RAB3GAP1,CCDC88A,SHANK2,BTBD7,SLCO1A2,SPHKAP,TET1,SMARCA4,SMARCE1,RIMS1,SNAP25,SNCA,MBD5,ZNF415,PALLD,MYO16,UNC80,SON,SOX5,BDP1,FNBP1,ENKUR,KDM4C,C11orf87,PBLD,SAMSN1,CEP68,RGL1,KLHL7,PLCB1,SYT1,COBL,DDHD2,AGTPBP1,TBCEL,SIN3B,TCF7L2,ZEB1,WASHC4,PCDHGB7,CLASP1,SYNE1,PCDHB4,PUM2,USP32P1,GPRIN3,FRYL,TF,ZFPM2,ITGB3BP,TJP1,ASXL3,TMPO,BEX4,CSMD1,TP53BP1,TPM1,TRPC3,PLEKHH2,CCDC14,WNT7A,RICTOR,GUSBP1,XRCC4,PCDH20,MICU3,CRB2,ZBTB38,EML6,ANKS1B,PLPPR5,ZFAND5,MAP3K12,CADM2,PRDM2,XKR7,SIGLEC10,MDH1B,PCDH15,NAV3,CAB39L,SLC17A6,GOPC,FZD3,DOCK8,KAT6A,SMIM8,FBXO36,NHSL1,SNX14,SOCS4" MicroRNA hsa-miR-325-3p:TargetScan hsa-miR-325-3p TargetScan 3.39E-133 1.90E-129 4.50E-132 4.15E-131 377 1727 "ACADM,ACHE,NCKAP5,ACTN2,NDRG2,ELFN2,ADCY2,ADCY6,ADCYAP1R1,ERMN,PLEKHH1,PWWP2A,KIAA1211,ADORA3,RNF150,ESYT2,KIDINS220,LCNL1,MTA3,KLHL13,CASKIN1,AK2,LRRC7,C1QTNF4,ABCD2,GOLGA7B,GPRASP2,DOC2A,AMH,AMPD3,CDC42BPA,PPFIA4,PPFIA2,PPFIA1,APLP1,APOC1,APOC2,AQP6,PLA2G4C,CADPS,MARK4,CAPRIN2,RASL11B,INSYN2B,ALDH4A1,ATP1A2,ATP2B2,ATP6V1G2,DOCK11,BACH1,HCN2,BCS1L,BMP7,FUBP1,OSGIN2,LDLRAD4,DIRAS1,CALM1,PTBP2,CAMK2A,BRSK2,HIP1R,CCNT1,CBFA2T2,REPS2,CDC25B,CDC27,CDH18,CLGN,NUMBL,CFL2,GPR37L1,CHN1,RAB3C,B4GALT6,DLGAP3,NRXN3,KIAA1549L,CLU,NMT2,CCDC151,IGLON5,COL9A1,LETMD1,AHCTF1,NRG2,CDC42BPB,ENTPD4,CLIP3,CNTNAP2,PPP6R2,DCAF4,GPRASP1,DCAF8,MATR3,MAML1,PHYHIP,DGKG,SCRN1,DBN1,ARMCX4,ARMCX2,JAKMIP2,GUCD1,MTX3,CCDC3,ARNT2,DMD,CALN1,DOCK2,RCAN1,GOLT1B,FAM135B,EDNRB,ANKRD46,EEF1A2,HEYL,CACNG7,RBM12,FAM13A,GPR61,EIF4G2,ELAVL2,CERCAM,ELN,EIF1,EMX2,EPB41,EPS8,ERBB4,GMPR2,HSPA12B,REEP2,ARMCX1,CLVS1,EFEMP1,FGFR1,MAD2L2,FOXF2,FOXM1,NOP56,FLYWCH1,C2orf88,AK8,CGREF1,GPR153,FUT9,NEURL4,GABBR1,FAM184B,RAPGEF6,NKX6-2,GART,CPLX1,FAXC,GBX2,CYP46A1,MMADHC,GFRA1,GFRA2,CSDC2,GK,COPS8,LUZP2,PCSK1N,DCLK2,GNAO1,GNG4,GPD2,GPR12,GPR26,GPER1,NUDT21,GPR37,CECR2,GRIK4,GRM7,PTPRT,KIF3A,PTPN5,COQ10A,GSTM5,IL1RAPL1,KAT7,LINGO1,GUCY1A2,RASSF8,PTGDR2,PACSIN2,HAPLN2,AGBL5,HP,NEGR1,HPR,IDH3B,RAB41,LRRC25,IGSF1,INPP1,C2CD4C,KCNB1,KCND1,KCNF1,KCNH1,CLVS2,KCNJ5,KCNJ9,KCNJ11,KLHL23,KCNN3,IPO5,KTN1,LIFR,PAXBP1,HECTD2,FGFBP3,NCOA7,C2orf80,ASPRV1,GPR155,NAT8L,MBNL1,MEF2C,POC1B,MMP16,MN1,MOBP,SAMD5,ADAM22,MT3,CTNNA3,MDGA1,SAMD14,LAYN,P2RY13,NASP,NCAM1,NEFM,NEUROD2,NFIA,ALDH1L2,NFIX,NFYA,NOVA1,PCBP3,NRGN,NUCB2,IGSF11,CHAMP1,OPCML,OPHN1,CLDN11,P2RY1,KCNK10,PC,PCSK1,PDE1B,PDGFRA,PFKFB3,OLA1,GDAP1L1,NOMO2,PIK3R1,PKM,FAM216A,PLEC,FTO,FXYD1,PNMA3,PMP2,PRRX1,PPP2R2C,PPP3CA,PRODH,NDUFS7,BCAS3,MDGA2,ANKHD1,RAB3A,ENOX1,RASGRF1,FEZF2,KHDRBS2,RDX,PRRT2,RFX3,PRIMA1,KLHL11,RNASE1,RIC8B,RNASEL,RPRD1A,RAVER2,ROM1,PCMTD2,BAALC,PRR5L,EMID1,HUNK,KCNIP1,AMER2,SATB1,ATXN7,SCN2B,LRRTM4,FNIP1,ITSN1,PPP1R9A,FBXO11,CTXN2,CLSTN1,FAM81A,ELMO2,GKAP1,ABTB1,CDK5RAP2,MAPKBP1,PALLD,MYO16,SCN3B,HECW1,MYCBP2,PEG10,ARHGAP26,RAP1GAP2,DDN,NFASC,C11orf87,POGZ,NACAD,NCDN,ELOVL4,PHLDB1,GANAB,AJAP1,FAM168A,MLC1,ARHGEF9,ANKRD28,ATP11A,ANKRD12,ROBO3,FAM208A,EHBP1,SATB2,NAT16,HHIP,CDH22,RELL2,BHLHB9,HEY2,FAM124A,RIMBP2,PRMT8,NTSR2,RUSC1,LRTM2,HEPACAM,CLIP2,KCNK12,LGI4,INTS3,CA10,PMEPA1,NAV2,AMN1,FZD3,MRPL47,MARCH8,RTN4,HNRNPA3,FBXO36,CERS6,RNF170,ADAMTS10,FRMD6,PRRT4" MicroRNA hsa-miR-148a*:mirSVR_lowEffct hsa-miR-148a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-132 7.53E-129 1.78E-131 1.64E-130 403 1968 "ABAT,RBM10,AS3MT,METAP1D,GPRIN1,CSMD3,FMNL2,DSCAML1,GALNT13,OSBPL1A,TBC1D14,OSBPL8,CC2D2A,C1QTNF1,ALAD,SPOP,CEP126,GOLGA7B,AMPD3,AMT,ZFAT,LRCH2,ANK2,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APAF1,DDO,CACHD1,TNRC6C,APP,AQP4,TMEM263,ASGR1,DDX3Y,TMEM108,ATM,CCDC181,SLC4A4,ATP2B3,MTMR9,RIPK1,BBS2,MPDZ,RGS9,DCAF5,CACNA1G,CA8,CACNA1A,CALB2,PTBP2,CH25H,RUNX1T1,KRIT1,CBFA2T2,TMEM257,ENTPD6,CDC25B,ZMYM4,CFL2,CHGA,CHN2,CASC2,CPNE6,PLAA,KIAA1549L,CLCN4,FBXO7,TJP2,MAP4K4,CNTN1,AKAP7,SUMF2,SLC4A7,SLC4A8,RCHY1,AHCTF1,CPS1,FAM171B,C2CD2,CREM,CREB5,AKAP12,HAPLN1,ANKRD44,TRIM69,FEZ1,MICAL2,PDE4DIP,KIAA0040,KIAA0408,FRMPD4,DGKG,DNAL1,JAKMIP2,ZEB2,CEP170,MAGI2,KLHL3,SV2A,FAM107B,DLG4,EXOG,GRIN3A,HS3ST4,OLIG1,NYAP1,DMTF1,DTNA,DNAJB6,ABCC9,AASDH,EDNRA,EDNRB,YAF2,SH3GLB1,EFNB3,PHF20L1,MBNL2,ABI2,AASS,LPAR6,PLEKHA1,CALCRL,DCTN4,EPB41,LRRC23,EPHA5,GPHN,SRRM1,ZNF549,CDKL3,RTN3,ADGRV1,EYA1,F3,FAM198B,SCML2,CORO2B,DLC1,ATP8A1,FCGR1A,CHST15,FKTN,ZSCAN30,TESK2,FER,FGF12,FHL1,POLK,SUCO,MEX3B,FOXG1,PCYOX1,SORBS1,SMC2,KHDRBS3,MSANTD4,DKK3,HRASLS5,GABRG1,ZNF274,NCKAP1,ZNF559,DISC1,ACSS1,GATM,NFU1,CRCP,HPGDS,GLS,TNRC6A,STARD3,ZNF638,KDM2B,GNAS,WDFY3-AS2,GPR34,NUDT21,GPR37,GRIA2,GRIK2,SERP2,NR3C1,COQ10A,LINGO1,GUCY1A1,WIF1,MAN1B1,HNF4G,HNMT,HNRNPK,ZDHHC15,SMAP1,ZIC5,RBPJ,DISP2,IL11RA,BRINP3,INSM1,LRRTM3,KCNA4,KCNC1,KCNC2,KCNMA1,KIF2A,IPO5,LAMP2,LMO1,LMO2,SYTL4,C2orf80,MBD1,CHIC1,LDLRAD3,LRP1B,SRSF12,KITLG,MITF,MOG,MSI1,ADAM22,SCG3,MTTP,MYO6,FXYD6,NCAM2,NEFM,SLCO1C1,VWA2,NTRK2,DDR2,OXTR,PAH,PCMT1,PDE3B,PDE4D,HERC2P3,SEMA5B,PIK3CD,JAKMIP1,PRIMPOL,LRP12,SCHIP1,ING3,FAT3,IRX1,CRLS1,PPP3CA,KANSL1,PRKAB2,PKIA,MAPK9,GDPD1,BCAS3,WBP1L,QRICH1,CNTLN,PTCH1,ANKHD1,UHRF1BP1,MTMR10,PTPRB,TUG1,RAB5B,CEP97,ZNF793,NWD1,ARID4A,RFX4,RGS7,PRIMA1,PBRM1,ZFHX4,ROBO1,ROBO2,MRAP2,NEK11,RPL15,BAALC,SPIN3,GLDN,ACER3,TCP11L1,RPS6KA2,ABCA11P,KCNIP1,RTN1,FOXRED2,SEMA6D,ATXN2,LRRTM4,SCP2,TNFRSF19,SMPD3,SLC30A10,SOX6,SFPQ,TRA2B,COPZ1,HSPA4L,MYO18A,NTNG1,PKNOX2,SEPHS1,SLC8A1,ARHGEF40,SIRT2,SHANK2,SLC14A1,EFHD1,CDK5RAP2,INTS9,ANKRD36,LIMCH1,SNAP25,KIF13A,SNRPN,RBM34,SCN3B,DOP1A,MYT1L,ZCCHC24,NMNAT2,ZBTB43,RBM26,NFASC,TAB2,PBLD,SAMSN1,ERBIN,MAPK8IP3,ZSCAN29,JMJD6,SYNE2,C3orf70,TMEM150C,ANKRD28,C12orf76,MMS19,EXOC7,TAL1,FAM208A,FBXW11,KLHL4,EHBP1,ACSL6,WDR7,SYNE1,DOCK9,TMEM151B,USP32P1,TNS2,RNF216P1,ITGB3BP,LEFTY2,AP4E1,SLC44A1,ARL10,TJP1,BHLHB9,ERCC6L2,HEY2,TMPO,KCTD2,TNS1,TP53BP1,TPD52,RASD2,NPL,SYNPO2,PPIL6,DCBLD1,ANKRD20A2,RPRM,AMOT,UGT8,USP1,BCL2L13,CLDND1,GUSBP1,KCNT2,FMN2,CELF4,ZSCAN26,SYNC,CADM2,STMN4,ITM2C,PLSCR4,C12orf4,PDSS2,UBE3B,KAT6A,CERS6,JMJD1C,TIGD6,RNF170,SSPN,KLHDC1,FRMD6,RNF146,GAN" MicroRNA hsa-miR-1322:mirSVR_lowEffct hsa-miR-1322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.50E-132 8.45E-129 1.99E-131 1.83E-130 347 1477 "RALGAPA1,CLK4,TKTL1,FMNL2,KLHL32,TMEM132B,ADD3,AXIN2,BRAP,SLC12A5,ESYT2,BEND6,SLC24A4,SNX32,OSBPL1A,CC2D2A,ZNF578,PCDH10,APC,EPB41L5,ALS2,VAT1L,TNRC6C,ASPH,PCDHGB4,DPY19L3,BBS2,MTMR2,JAZF1,SGCE,C5,CA12,CALB1,KALRN,CAMK2D,TRIM41,MAP7,RUNX1T1,ARHGEF25,LRBA,LOC730101,TIGD7,CCPG1,FOXN3,ASIC3,CHN2,CLTC,TJP2,MAP4K4,CNR1,AKAP6,COL9A2,ACBD5,ZNF521,CPS1,OSBPL3,PDE4DIP,CST3,PLXNA4,CMTM5,RUBCN,SNPH,PHF19,ZFYVE16,ZNF337,TBC1D5,KCTD8,TMEM170A,ARMCX2,DNAJC6,JAKMIP2,DGCR5,MFAP3L,MAGI2,KLHL3,G3BP2,RABGAP1L,WDR20,ZNF582-AS1,HS3ST2,NR1D2,DOCK2,PDCD6IP,ARRDC4,ECM2,DYRK1A,DNM1L,GOLT1B,EDNRA,ANKRD46,TMTC1,OPTN,YAF2,AASS,EIF4G2,IRAK4,TENM1,SIRPB1,EXTL2,KATNAL1,ARMCX1,TUBA1B,ZNF589,SLC9B2,FGF1,FGFR1,CAMSAP1,SCARA3,TRMO,NBEA,SORBS1,TPK1,ZNF605,CGREF1,AP4B1,GABRA5,NCKAP1,TMEM8B,INPP5K,CPLX2,CPLX1,IGSF5,SULT1C4,MSTN,MALT1,RAB30,GLRB,TNRC6A,MSL3,LOXL3,ADGRA3,TDRKH,MCHR1,TMEM121B,GRIA1,GRIA4,NR3C1,GRM2,GRM7,FAM19A2,PTPN5,AP4S1,RABL2A,GUCY1A1,ATOH8,CELF3,WIF1,NCKAP1L,HNRNPK,HSPA1L,IDH3A,LINC00667,C2orf72,IGFBP1,RIPPLY2,KCNA2,KCND1,KCND2,KCNJ3,KCNN2,KLRC2,A1BG-AS1,SYTL4,HECTD2,NCOA7,GPR155,MBD1,CHIC1,MIA2,SESN3,BCO1,MSR1,NRBP2,MYO5A,MYO6,NAP1L2,FXYD6,NDP,NDUFA5,NEUROD1,NF1,ALDH1L2,NFYA,NPY,SLC11A2,NRCAM,SETD4,KCNK10,CNTN3,PCDHGC3,PCSK2,PDE3B,GNG2,CDK14,ZNF655,PLCB2,PLP1,MTRF1L,STRN3,LRP12,SLC36A4,PPP2R5C,PPP2R5E,KANSL1,SIDT1,GON4L,TMEM104,UHRF1BP1,PXK,ZSCAN32,PTPRB,OCIAD1,PTPRD,PTPRO,FAM120C,ACSM5,USP47,ZCWPW1,TRIM68,REV3L,SEC61A2,PBRM1,KLHDC8A,ALG9,ARMC5,RAVER2,CARF,GSTCD,RORB,TMEM206,ELP2,MRAP2,ACER3,LRRK2,RMI1,ATXN2,LRFN5,SCN2A,SCP2,FNIP1,GALNT10,FAM102A,SH3GL3,AMBRA1,FBXO11,ZNF365,LRRC55,SLC6A8,SLC9A5,SLC12A2,ELMO2,BTBD7,SLCO1A2,LGI3,SLC22A4,MBD5,TMCC1,USP33,FAM219A,TRERF1,TNIK,BDP1,FNBP1,ZSWIM8,ENKUR,ERC1,PEG10,CDK19,NFASC,CLASP2,STOX1,EPB41L3,ELOVL4,SEPT3,AJAP1,FGD4,FNDC9,SYN1,COBL,TACR1,PJA1,EXOC7,KLHL4,ANO4,EHBP1,TCF7L2,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,DOCK9,RALYL,PCDHB10,PCDHB4,AHCYL2,ITGB3BP,GPR161,SLC44A1,TMEM9,HEY1,TLL2,ERCC6L2,LRRC8A,BEX4,TPM1,CDK20,C9orf85,ZMYND8,RUSC1,RFTN2,MTCH1,VLDLR,BEST1,NSD2,RICTOR,GUSBP1,XRCC4,MICU3,TRIM9,ZNF74,ZNF184,EML6,PLPPR5,SLC38A1,STOX2,SCG2,GAL3ST3,EPM2A,FAM13C,FZD3,RTN4,UBE3B,PAK5,NETO1" MicroRNA hsa-miR-1294:mirSVR_lowEffct hsa-miR-1294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-132 1.05E-128 2.47E-131 2.28E-130 371 1683 "TTYH1,SERPINA3,DGCR6,ASIC1,GALNT16,CCDC85A,TMCC3,ADD2,ADD3,PNMA8B,SORCS1,GRAMD1B,USP31,UNC5A,SNX30,KIDINS220,AP1B1,RTL9,KIAA1324,MAP4K3,PHF12,CNTNAP1,AMER3,BCAS1,PPFIA3,SHROOM2,AQP4,AQP6,SFMBT2,SEMA4G,CDK13,CAPRIN2,ALDH4A1,ATM,SLC4A4,ATP2B3,ZNF583,TTC9B,SNAI3-AS1,ADGRB3,BCHE,CFLAR,SYNJ2,NIPA1,CDK5R2,CA12,CACNB2,CALM1,VXN,BRSK2,KYAT1,CCK,CD38,ENTPD6,LRRFIP1,LARGE1,IGFN1,CFL2,SOCS6,CASC2,NDST3,C7orf61,RAB33A,ABCG2,DNAJB5,QKI,BTF3L4,COL11A2,AHCTF1,CNRIP1,MFSD4A,ZNF385A,CREM,TRIM69,CSF1,RGS6,LRIG1,CSNK1E,IPCEF1,VCAN,KIAA0040,APPL1,UBXN2A,CFAP61,RIMS2,DCAF4,FAM131B,ECE2,KIAA0408,BOC,CTIF,DCT,ZBTB24,PLEKHM1,HP1BP3,TMEM130,RHOBTB1,WDR20,KBTBD11,EXOG,RAB39B,CPEB2,RCAN1,DYRK1A,E2F5,EBF1,FAM135B,ANKRD46,SGK2,HEYL,FAM13A,PHF20L1,SUGP2,EGFR,EGR3,ASB3,PLEKHA1,C3orf18,EMX2,PLEKHO1,MTSS1L,EPHB1,ANKRD13B,CDHR1,EYA1,GMPR2,MRVI1,DLC1,CHST15,FCGRT,ZNF589,SLC9B2,GTF2IRD2,FGF12,MEX3B,SGIP1,TACC2,UFM1,PDLIM5,USP21,ATP2C1,ERGIC3,CGREF1,MSANTD4,HHIPL1,DOT1L,NRG3,TVP23A,GABRA1,CHL1,GABRG2,GAD1,HBS1L,IQGAP2,SIGLEC8,MTHFD2,SEPT9,GATM,IGSF5,SULT1C4,GGT7,MSL3,STARD3,OS9,POLL,GNAS,LNX1,PRUNE2,FUT10,GPER1,EML4,TMEM121B,PCLO,GRB10,GRIA4,GRIK1,SPACA9,PRDM5,ZNF496,RNF165,MFSD2A,ADAMTS6,FAM222A,RASSF8,NXPH3,ATXN2L,KLF12,ZDHHC15,HSF2,LRRC75A,FAM95B1,LINC00667,LRRC25,SCIN,LIX1,IL11RA,SLC35G1,OLFM3,KCNC2,CLEC18A,LYPLAL1,CHIC1,MEIS2,PPM1L,AFDN,MN1,GIT1,COMMD5,CCDC80,MT3,ZNF92,MTR,MYCN,MYH6,NCAM1,NEUROD2,ALDH1L2,NTRK2,NUMA1,PBX1,PCSK1,PDE1C,PDE2A,SLC10A4,ANLN,CCSER2,FAM216A,PLCB2,SLC25A23,MTRF1L,PURG,TRHDE,RC3H2,SPATA6,PILRA,PPP1R1A,TATDN3,PPP2R2B,MAPK9,GDPD1,SLC22A23,PIGG,CNTLN,PTAFR,NCR3LG1,MTMR10,TMEM260,STK32A,PTPRB,PTPRD,PTPRO,PPP2R3C,SLC25A48,ATG16L1,OXR1,ZDHHC14,BSDC1,SLC6A15,RGS10,RGS12,RIC8B,CCDC82,SETD5,ARMC5,CARF,CYB561D1,CCDC25,RPL15,SPIN3,GLDN,ACER3,PTGR2,FAM161B,MEG3,CLIP1,TRAPPC13,ATXN2,ATXN7,SCN2B,SCN4B,SOX6,GALNT10,COPZ1,ZFP30,ARX,CPEB3,HKDC1,AMBRA1,FNDC3A,SEC31A,RPH3A,URGCP,EPN2,RUFY2,SLC8A3,CCDC88A,SLC11A1,ATF7IP,MAPKBP1,SNCA,SNRPN,MYO16,UNC80,SCN3B,DOP1A,SON,WDTC1,ZCCHC24,SOX15,KDM3A,SP2,GLT8D1,KDM4C,UNC5B,ZC3H13,NPAS3,TAB2,MAPK8IP3,NEK4,SEPT8,ZFR2,ANKRD28,CAMTA1,ADGRL3,TBCEL,SIN3B,SATB2,CUX2,ZEB1,TPCN2,WDR7,SYNE1,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,HIF3A,ENHO,HEY2,DAAM2,KCTD2,WBP2,DOK6,ZNF346,TRIO,DCBLD1,CLEC2L,FRRS1L,MICAL1,BEST1,ZNF781,CLDND1,SF1,GPR158-AS1,EML6,ZNF225,EMSY,PRTFDC1,TMEM178A,PCDH15,FAM47E,MVB12B,RGS7BP,JMJD1C,RNF170,KLHDC1" MicroRNA hsa-miR-124*:mirSVR_lowEffct hsa-miR-124*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-132 1.28E-128 2.99E-131 2.75E-130 375 1719 "ASIC1,SLC25A25,KLHL32,ADCY2,GALNT13,SORCS1,PLEKHH1,AP2A2,OSBPL8,SMIM17,ALCAM,BBOX1,AMPH,CDC42BPA,LRCH2,ANK3,BCAS1,TNRC6C,API5,AQP4,TMEM263,TMEFF1,ARNTL,PDE8B,MARCH3,CAPRIN2,CCAR2,DDX3Y,ATP1A1,ATP1B3,ATP2B3,RNF182,N4BP2L1,BMP7,MTMR2,LDLRAD4,CACNB4,CAMK2A,CAMK2B,CANX,VXN,SPAG9,ARHGEF2,CDH10,LGI1,MAGI1,CCPG1,CACNA2D2,NDST3,QKI,CNGA3,TMEM155,AKAP7,ARMC8,LETMD1,ABI3BP,GAL3ST1,BAG4,MYRIP,ZNF385A,CDC42BPB,C2CD2,CREB5,CRMP1,RNF14,ANKRD44,CSF1,LRRC3B,CSNK1G3,ATRNL1,CHD5,DZIP3,GREB1,CYBB,KIAA0408,KATNAL2,TOX,KIAA0513,MATR3,GIT2,DCC,ARMCX2,YTHDC1,HEPH,GSDME,SNAP91,SPOCK3,RAB39B,DMD,DNM1,PDCD6IP,DTNB,DNAJB6,ABCC5,E2F5,WDPCP,FAM135B,EDN3,HIPK3,RASGRP1,YAF2,SH3GLB1,EFNB3,FAM13A,PHF20L1,EGFR,MBNL2,RASA4,ELAVL2,STARD3NL,USPL1,EN2,OLIG2,EPB41L1,COQ7,EPHB1,STX2,SRRM1,IGSF6,PIPOX,ANKMY1,RASL12,EYA1,F5,SH3YL1,ACSL4,DLC1,FCGR1A,CEP78,CHST15,FECH,SEC24B,FER,PRKAG2,POLK,MEX3B,AGAP3,WDR83,NBEA,TACC2,POMT1,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,ST6GALNAC3,CSPG5,PHYHIPL,GAB1,GAD2,HBS1L,FAM120B,B4GALNT1,GAP43,ERAP1,ZNF559,DISC1,SULT1C4,WASHC2A,AHDC1,ADAM28,PPARGC1A,TCERG1,SPIN1,GLI2,GLYR1,TNRC6A,GNAL,PSRC1,FUT10,ATP2B1-AS1,GRIA2,GRIA4,GRIK2,ADAMTS13,GRM1,TMEM25,SOX21,MAP4K5,MAEL,UBE2QL1,HPS5,ZHX1,PTGDR2,HMGCR,TLX1,ZDHHC15,NEGR1,LRRC75A,C5orf24,TJAP1,PLD5,BRINP3,ZNF678,INSM1,METTL21A,KCNA1,KCNJ10,KCNK1,KCNN3,KHK,KIF5C,KIT,STXBP5,KTN1,LAMP2,SYTL4,VWA5A,NCOA7,LSS,MATN2,LDLRAD3,TM6SF1,MEIS1,MEIS2,KCTD6,POC1B,AFF1,XRRA1,CD200,BCO1,MYO9A,NAP1L1,VWA2,SLC11A2,OLR1,OPHN1,TREM2,PDE4D,GNG2,CYTL1,GDAP1L1,TMIE,KCTD15,NLE1,JAKMIP1,MTRF1L,PLXNB1,PRIMPOL,PPP1R1A,PRKCB,MAPK4,MAPK9,DCHS2,BCAS3,VPS13C,PIGG,CNTLN,PTCH1,ANKHD1,UHRF1BP1,PTHLH,NKAIN1,TTC13,TUG1,PPP2R3C,PRRT2,RFX4,RGS12,RIC8B,RNASEL,RPRD1A,ZFHX4,C12orf49,ALG9,CYB561D1,ROBO1,ROBO2,BAALC,SPIN3,GLDN,LGR4,HUNK,ZNF568,SOX6,GALNT10,SCAF8,ITSN1,SH3GL3,FBXO11,CNKSR2,NUBPL,SLC1A3,RPH3A,PPP4R3A,SLC6A1,KANSL3,NAPB,ATF7IP,SLCO1A2,SLC22A4,DMRTC1,MBD5,SNRPN,MYO16,DOP1A,WDTC1,SOX2,BDP1,TSNAXIP1,SP4,UHRF1BP1L,MYCBP2,KIF1B,TSPYL2,SAMSN1,SSTR1,TTBK2,DIP2A,KANK1,SEPT3,SYT11,FGD4,VAMP1,SYT1,UNC5D,WWC1,TBCEL,FBXW11,KLHL4,SATB2,SZT2,SYNE1,PCDHB6,AHCYL2,SIK3,TF,FAM200B,C18orf54,TGFBR3,AKTIP,THBS4,GZF1,ZFP91,RIMBP2,KCTD2,R3HDM1,CSMD1,C5orf64,PIK3R5,TPD52,TPM1,NPL,C9orf85,RUSC1,ZKSCAN5,FAM155A,UBE3A,AMOT,LINC00689,BCL2L13,XPO1,XRCC4,AGMO,ZNF138,ZNF177,EML6,SMARCAD1,PMEPA1,PRDM2,DNALI1,LRP8,STOX2,RNF103,GAL3ST3,DOCK8,UBE3B,CASC15,TRAM2-AS1,SSPN,PIANP,FRMD6,RNF146,SLC4A10" MicroRNA hsa-miR-597:mirSVR_lowEffct hsa-miR-597:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.14E-132 2.33E-128 5.44E-131 5.01E-130 342 1440 "TTYH1,AS3MT,SYS1,ADAR,PSMG3-AS1,ADD1,FZD9,BEND6,CC2D2A,ARHGAP20,SYT13,ANK3,CNIH2,SUGT1P4-STRA6LP-CCDC180,APBB2,MAGEE2,VAT1L,PPFIA3,SHROOM2,AQP4,ALDH4A1,SLC4A4,DPY19L3,MYOM1,ADGRB3,LINC00847,KSR1,DST,LINC00906,JAZF1,MYRF,CA8,DDR1,CACNB4,KALRN,HAP1,CAMK2B,MAP7,PRC1,KYAT1,CBFA2T2,SCARB1,AP4M1,SEPT7,CDH2,CDH8,CLGN,SRSF11,CNOT8,JAM2,NDST3,LSMEM2,CLTC,VAX2,MAP4K4,AKAP6,COL4A5,ABI3BP,ZNF521,CNRIP1,CP,C2CD2,ANKRD44,RGS6,SEC24C,ARHGEF10,SUSD5,NCAN,CNTNAP2,KIAA0040,GREB1,CTNND2,RIMS2,ST18,DCAF4,USP6NL,CCDC144A,CYBB,KIAA0408,GAPVD1,TCAF1,DCAF8,ZFYVE16,EARS2,LONRF1,BRINP1,AIF1L,YTHDC1,DGCR5,CEP170,BLOC1S6,SV2B,RABGAP1L,ARNT2,GRIN3A,CPEB2,PDCD6IP,MAMLD1,DYRK1A,DNM1L,GPR61,ABI2,TNK2,EML1,STARD3NL,EMX2,ENO2,ANKRD13B,ERCC2,ZNF549,CDHR1,ETV1,F8,TAOK3,PRKAG2,FOXF2,PCYOX1,SYNCRIP,FOXO3,EVL,EFCAB2,WDR83,NPTN,NSG2,GPR153,ADGRA1,SARAF,GABRA2,ZMYND11,ARPP21,ZNF234,ZNF559,DISC1,SULT1C4,MSTN,PPARGC1A,LYVE1,GK,TXNL4A,COPS8,TOX3,GNG4,GPT2,ADGRA3,PRUNE2,RAPGEF4,GRIA1,GRIN2D,BTN2A1,BVES,PSIP1,TOX2,C1orf94,MAN1B1,ELOVL5,ZDHHC15,TCEAL6,FAM95B1,LINC00667,BRINP3,INPP5B,KCNJ10,KCNK1,A1BG-AS1,MAN2A2,MAP4,MBP,MDM4,LRP1B,MEIS2,MMP16,CD200,ZNF680,CCDC80,PTOV1,MT1M,RTL5,NAP1L1,NAP1L3,ZC3H12B,NDUFA5,NF1,OPCML,SNTG1,PBX1,PDE3B,PFKFB4,OLA1,CDK14,SERPINE2,ZNF655,A2ML1,KCTD15,ST8SIA5,PLP1,PLXNB1,C11orf49,PDZRN4,MAPKAP1,LRP12,SCHIP1,ING3,RETREG2,PPARA,MED1,PPM1B,LRRN3,PPP2R5C,RASGEF1B,PRKACB,PRKCZ,KLK6,BCAS3,VPS13C,DEF8,GDPD2,SNRK,QRICH1,CNTLN,PTCH1,BDNF-AS,PTHLH,PTN,TMEM260,PTPRG,PTPRH,PTPRO,PEX2,MARCH1,PID1,USP47,PLEKHB2,ENOX1,ZDHHC14,SLC6A15,ZMAT4,RET,ERI2,GTDC1,RFX3,ARHGEF10L,RIC8B,LGI2,CCDC82,RAVER2,PNMA8A,ATP8B4,HUNK,WLS,KCNIP1,ZNF331,FAM192A,HOGA1,SCP2,FOXRED1,SH3GL3,FERMT1,CHD9,SEC31A,NUBPL,SLA,RUFY2,KANSL3,SLCO1A2,SPHKAP,ANKRD36,SNCA,KIF13A,FAIM2,FAM126B,DOP1A,MYT1L,SP2,ZC3H13,CDK19,TSPYL2,C11orf87,TAB2,EPB41L3,ZC4H2,LARP4,LRRC4,NXT2,STAU1,KANK1,SUPT5H,ZFR2,ARHGEF9,PLCB1,SYT1,ANKRD12,KAZN,WWC1,ANO4,VWA3A,ACSL6,RPGRIP1L,SZT2,WDR7,AZIN2,DOCK9,SLC19A3,PUM2,TEX15,ARL10,TIAM1,MTMR14,TJP1,ACTR6,DDHD1,TLL2,CSMD1,SEZ6L,RGMB,ZNF346,PRMT8,TSC1,SGK3,AMOT,VLDLR,WIPF1,NSD2,CLDND1,SLC47A2,KCNT2,FMN2,LYPD6,TCEAL7,ZNF138,CELF4,PLPPR5,PRDM2,LINC02210,HPS4,FAM13C,ST7,FAM219B,MSRB3,NHSL1,SLC39A12,FXR1,PRRT4" MicroRNA hsa-miR-624*:mirSVR_lowEffct hsa-miR-624*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-132 2.97E-128 6.92E-131 6.38E-130 319 1255 "ACADM,EMILIN3,GPRIN1,KLHL32,ADCY2,ADCY6,ADD2,PLEKHH1,KIDINS220,SLC44A5,ALCAM,OGT,ANK2,LCORL,APBB1,MIER1,CADPS,CDK13,MARCH3,PCDHGB4,EIF4G3,STX16,RNF182,BBS2,DCAF5,DST,C1QC,SGCE,GPC2,CALM1,TRIM41,PRC1,CCNH,SCARB1,TMEM257,CDC27,CDC42,L3MBTL4,CHN2,B4GALT6,LHX2,KMT2C,NMT2,QKI,IGLON5,ARHGEF6,IQCK,BTF3L4,SLC4A7,AHCTF1,PREPL,AKAP12,HINFP,ANKRD44,CSF1R,LRIG1,ATRNL1,RIMS4,PDE4DIP,FAM169A,CTH,DCAF4,CCDC144A,BOC,DOCK4,HDAC4,TM9SF4,TMEM170A,TOMM20,DBI,CEP170,BLOC1S6,DDX46,ALKBH8,PLPPR4,SNAP91,DLG2,DYNC1I1,CPEB2,DNAJB6,ABCC9,E2F5,EBF1,ATL1,HIPK3,SEMA3D,RBM12,YAF2,EFNB3,PHF20L1,ABI2,TENM1,ERCC2,ETV1,ANKMY1,GMPR2,NRN1,F5,FAM198B,TAOK3,DLC1,FCGR1A,ST3GAL6,CEP78,FKTN,ZSCAN30,ZNF589,FGFR1,SUCO,FOXO3,ANKFY1,PDLIM5,FAM49B,KHDRBS3,NSG2,DACH2,CGREF1,SARAF,STAG2,GABRA2,GAP43,SIGLEC8,DISC1,GATM,NEU3,TUBGCP4,MSTN,PPARGC1A,BRD8,GPR34,RAPGEF4,GRIA2,GRIA4,PLCD4,GRM7,FAM19A2,RABL2A,ATOH8,MIER3,VSIG4,ELOVL5,HNF4G,SMAP1,HTR2A,USP54,ZNF678,ITPKB,JAK1,KCNA4,KCNA6,STXBP5,LAMP2,SYTL4,ZFYVE27,CHIC1,LRP1B,ZNF680,MYO9A,NAP1L1,ZC3H12B,NDP,HCN1,OPA1,PCDHGC3,PCDH9,PCSK5,PDE3B,PDE4A,GPR85,GNG2,BEST3,CDK14,SEMA5B,SNX10,XRN1,PLCL1,FTO,LRP12,PRRX1,ING3,FAT3,TMEM235,MINDY2,PPP2R2C,CRLS1,PPP2R5C,PPP2R5E,PPP3CB,KANSL1,TMEM104,CNTLN,MTMR10,ZIK1,PTPRN2,FAM120C,PEX2,ACSM5,ZSCAN2,TUG1,CEP97,PLEKHB2,RAD51D,SH3TC2,FAT4,ROGDI,ZYG11B,GTDC1,ZDHHC4,MRPS18A,RNF220,SLC25A36,RIC8B,ZFHX4,ROBO2,RORB,MRAP2,ZC3H14,ATP8B4,ADAL,ABCA11P,HSD11B1L,YJEFN3,RTN1,RMI1,SEMA6D,ATXN7,SCN2A,SCN3A,PRCD,SLC30A10,PPP1R9A,CPEB3,CHD9,CNKSR2,DZIP1,ZNF365,DHX30,PKNOX2,SHANK2,NAPB,RCOR3,ANKRD36,MYO16,KDM3A,NMNAT2,CLUAP1,TEX2,PEG10,DBNDD2,C11orf87,ERBIN,ZSCAN29,NEK4,CEP68,SULF2,SEPT3,NSFL1C,ARHGEF9,COBL,CAMTA1,UNC5D,KLHL4,TCF7,TRIM2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,USP32P1,AHCYL2,SIK3,ZFPM2,CRB1,NR2E1,SYNPO2,AMACR,STXBP4,ZMYND8,FNDC5,DCBLD1,TSN,TSC1,TTTY15,HIRA,UGT8,SLAIN1,FLRT2,VIPR2,RICTOR,ZIC1,ZIC2,ZNF24,KCNT2,TRIM9,SLC26A10,LYPD6,EML6,EMSY,RGMA,EVI5,HPS4,ITM2C,MVB12B,FAM13C,MRPL47,DOCK8,ACTR3B,FAM219B,MSRB3" MicroRNA hsa-miR-27a:mirSVR_highEffct hsa-miR-27a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.32E-132 4.11E-128 9.57E-131 8.81E-130 349 1501 "RALGAPA1,NCKAP5,SLITRK1,CCDC85A,GRAMD1B,ADORA1,KIAA1211,ADORA3,PTCHD1,OLMALINC,ZNF608,INTS2,HACE1,WDR35,TAOK1,SEMA6A,ALCAM,DPP10,ANK2,ANK3,SEMA7A,PKP4,APBA2,GPAM,DDO,VAT1L,ASPH,NCOA1,ATP1A2,STX16,ATP2B1,ZNF582,RNF182,NOL4,RIPK1,TTC9B,NRP2,PROM1,CDK5R1,CACNA1A,CACNB2,VSTM2A,MTMR7,INA,SCARB1,C1orf52,ZMYM4,MAGI1,CIART,CFL2,ADGRG1,CASC2,MS4A7,KMT2C,CLCN3,NRXN1,QKI,NIPBL,CNN3,ARHGEF6,AKAP7,ARMC8,LETMD1,SLC4A7,ZFP28,CHD1L,ZNF385A,SLC35F1,PNKD,CRMP1,HAPLN1,GDA,SEC24C,LRRC3B,SUSD5,VCAN,EDRF1,HDAC9,GAPVD1,RIPOR2,DCAF8,TOX,LONRF1,KCTD8,DGKB,TMEM170A,PABPC5,DNAJC6,C8orf34,POM121,SNAP91,CHRDL1,GRIN3A,NR1D2,RCAN1,ARRDC4,DTNA,DNM1L,E2F5,EBF1,FAM135B,EDNRA,TMTC1,FAM13A,EGFR,MBNL2,LPAR6,ASB3,EIF5,ELAVL2,RGS17,CALCRL,EN2,EPB41,RCAN2,EYA1,EZH1,HSPA12B,TOMM40L,TESK2,KIAA1109,FGF1,FGF12,FGF13,FGF14,SUCO,CAP2,RGPD5,ARFGAP2,DACH2,ST6GALNAC3,NSG1,AP4B1,BRSK1,OGA,NEURL4,GABRB3,CAB39,BRPF3,NEK6,NCKAP1,IQGAP2,ERAP1,DISC1,NEU3,ARFIP1,PCDH17,PPARGC1A,GK,GLI2,GLS,TOX3,ZNF638,ADGRA3,GPD2,GPM6A,GPR37,GRIA4,NR3C1,GRM5,RNF165,RNFT2,FAM222A,MAEL,ZHX1,MIER3,CFAP126,HSPA1L,MSL1,SOWAHA,ZIC5,ZNF678,INPP1,NME9,KCNJ16,KCNK2,CREG2,KLRC2,STXBP5,PAXBP1,HECTD2,ARHGAP12,NCOA7,C2orf80,SMAD1,SMAD9,MARK1,LYPLAL1,MAT2A,AQP11,MATN3,MBD1,SYT9,MEIS2,KITLG,MOBP,ERICH3,ZNF680,MRPL42,MXI1,NAP1L2,P2RY13,NCAM1,NEK1,NF1,OTOGL,NFE2L2,NOVA1,PCDH9,PDE3A,PDE3B,PDGFRA,PRIMPOL,RC3H2,LRP12,SEPT4,POU3F2,PPM1B,PPP3CA,CEP41,PKIA,PRKCB,PKN2,MAPK9,GRAMD1C,HYDIN,DCHS2,RELN,PIGG,CNTLN,PTAFR,PLPPR1,MTMR10,ZSCAN32,QDPR,SH3TC2,FAT4,FAM184A,ENOX1,ZNF493,ARID4A,RET,REV3L,ERI2,RFX3,PBRM1,RNASEL,ZFHX4,CCDC82,SETD5,TMLHE,RORB,ELP2,FBXW7,ATP8B4,MEG3,NCBP3,TRAPPC13,TRIM46,ARX,CPEB3,SHC4,HKDC1,MAGI3,CHD9,PAAF1,SLA,EPN2,SLC6A1,SLC8A1,KBTBD4,ZNF334,TET1,CPEB4,RCOR3,SNAP25,TMCC1,TNIK,BDP1,KDM3A,KDM4C,PEG10,KIF1B,TROVE2,COLGALT2,STOX1,SSTR1,LARP4,ERBIN,NXT2,SEPT8,TTBK2,NECAB1,ARHGEF9,VPS13A,MMS19,TACC1,DDHD2,CAMTA1,TAF9,PDLIM2,TCEA1,SATB2,ZEB1,TRIM2,RPGRIP1L,CLASP1,RALYL,FRYL,SIK3,TF,FAM200B,CRB1,TGFBR3,THRA,ACTR6,CSMD1,TPM1,NPL,SYNPO2,PRMT8,TSC1,TTC3,CLHC1,CADM1,GORASP1,DNAJC12,PLEKHH2,ZNF709,BEST1,SLC13A3,XPO1,ZNF708,ZNF540,GPR158-AS1,MKRN3,FSTL5,ZSCAN26,SMARCAD1,DHX33,CA10,LRP8,TMEM178A,CAB39L,DOCK8,JMJD1C,VANGL2,ADAMTS10,NETO1" MicroRNA hsa-miR-3136:mirSVR_lowEffct hsa-miR-3136:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.48E-132 4.20E-128 9.75E-131 8.98E-130 367 1655 "VWA5B2,ASIC2,NBAT1,ACTN2,CSMD2,ARID1A,CSMD3,KLHL32,GALNT16,TMCC3,RNF157,ADD1,ADD2,ERMN,KIAA1211,ESYT2,ZNF608,HECW2,OSBPL1A,PLA2G6,ZNF578,LRRC7,ARHGAP20,KIF6,CDC42BPA,DPP10,EP400,MYH7B,PPFIA4,EPB41L5,LGR5,TMEM263,ZSCAN18,NUMB,DDX3Y,TMEM108,SLC4A4,ATP2B2,MTMR9,B3GALT2,NOL4,TTLL9,ADAM15,SNAI3-AS1,BBS2,KSR1,ARHGEF7,CASTOR3,MTMR3,SGCE,CACNA1G,DIRAS1,CALM1,PTBP2,CAPN3,CAST,SPAG9,LDB2,SCARB1,ZBED1,CDH8,DCLK1,LOC730101,MAGI1,CDO1,CCPG1,CACNA2D2,CHGB,EPS15L1,CLCN3,MAP4K4,TMEM155,SMARCAL1,ACBD5,MFSD4A,CDC42BPB,SNCAIP,CSF1,SUSD5,PDE4DIP,CNTNAP2,SLITRK5,PHF14,ST18,CX3CR1,CCDC144A,KIAA0408,DOCK4,FGFR1OP2,MATR3,DBN1,DNAJC6,ZNF804A,ELMO1,MFAP3L,KIAA0753,CEP170,RHOBTB1,AK5,WDR20,CHRDL1,DNM1,DMTF1,FAM57B,SLC25A18,PDCD6IP,GNE,DNM1L,EDN1,EDNRA,CNNM1,RASGRP1,SEMA3D,FAM13A,KMT5B,PAN3,PLEKHO1,EPHA5,ZNF549,CDKL3,MRPL10,TLR7,EXTL2,MRVI1,ATP8A1,CEP78,ZNF589,AMOTL2,MEX3B,IP6K2,PCYOX1,ANKFY1,SGIP1,NBEA,SMC2,UFM1,ARFGAP2,ERGIC3,DACH2,AP4B1,ZMAT1,MEGF10,GABBR1,GABRA1,CAB39,ILDR2,GALC,GAP43,ATP8A2,CPLX2,ALDH1L1,NFU1,ADAM28,GHR,LYVE1,RNPS1,SPIN1,RAB30,CBX1,LUZP2,GNAL,GNAS,PSRC1,GPD2,ATF7,TDRKH,MCHR1,GPER1,NUDT21,PCLO,ATP2B1-AS1,GRB10,GRIK2,ADAMTS13,GRM3,GRM5,ZNF496,MAEL,RASSF8,IGSF21,GABARAPL2,SYNPO,HNRNPK,ZDHHC15,OPALIN,EID2B,IDH3B,LINC00667,SHISAL1,HES5,LRRTM3,KCNA4,KCNA6,KCNC1,CLVS2,KCNK1,KCNK2,KPNA5,LAMP2,ARHGAP12,MAPT,CHIC1,MEIS1,KITLG,MKLN1,MN1,WDR49,MYO6,ZNF862,NF1,NFYA,IGSF11,OPCML,KCNK10,GLIPR1L2,SNTG1,PDE3B,PDE4A,ANLN,A2ML1,CCSER2,FTO,PRIMPOL,ANKRD16,SCHIP1,ING3,POU3F2,MINDY2,CRLS1,PPP3CC,RASGEF1B,PRKACB,CEP41,PRKCZ,EPDR1,LRRC49,SIDT1,PIGG,PTN,PTPRD,PTPRE,PTPRG,PTPRZ1,ZNF615,TUG1,PPP2R3C,PID1,SH3TC2,RASGRF1,RASGRF2,RADX,RDX,SLC6A15,TRIM68,SLC25A36,RAVER2,ROBO1,RORB,TMEM100,EPHA10,RPL15,ARMH4,FBXW7,ZC3H14,FAM182A,FOXRED2,TNFRSF19,GALNT10,SGK1,ZFP30,FAM102A,PPM1E,NTNG1,AMBRA1,FHOD3,SLITRK3,ST3GAL3,SEC31A,ZNF365,DHX30,FAM214B,SLC8A1,RAB3GAP1,ZNF667,RCOR3,MBD5,FAM126B,MYO16,DOP1A,BDP1,SOX11,ENKUR,UHRF1BP1L,SPP1,KDM4C,KIF1B,NFASC,EPB41L3,ZC4H2,SS18,SULF2,ACSBG1,VAMP1,FNDC9,SYN2,MTCL1,EXOC7,ADGRL3,KLHL4,VWA3A,ZEB1,TCF12,WDR7,RALYL,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,HIF3A,TEX15,ZFPM2,ITGB3BP,ZNF106,TLR4,RIMBP2,RASD2,TPM4,SYNPO2,TRO,ZMYND8,PPIL6,TSC1,LRTM2,ZKSCAN5,SGK3,PITPNB,FLRT2,CCDC136,VAV2,KCNK12,ZBTB14,ZIC3,ZNF24,ZNF45,SPHK2,TMEM237,SPIRE1,SMARCAD1,SLC38A1,HPS4,GAL3ST3,CAB39L,ITM2C,PARP11,EPM2A,RGS7BP,SMIM8,JMJD1C,ZNF248,RNF170,KLHDC1,FRMD6,SLC4A10,LAS1L" MicroRNA hsa-miR-1255b:mirSVR_lowEffct hsa-miR-1255b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.04E-132 4.51E-128 1.04E-130 9.61E-130 365 1638 "ABAT,DGCR6,ASIC1,SYS1,ACTN2,GALNT16,KLRC4,BRAP,SLC12A5,CDC7,GRAMD1B,PTCHD1,SLC24A4,ZNF578,C1QTNF3,LRRC7,FAM135A,OGT,USP28,PPFIA4,PKP4,CNTNAP1,APAF1,DGKZ,UPRT,PHYHD1,CPNE5,SPTBN4,MARCH3,ZBTB10,NCOA1,DDX3Y,STX16,ZNF583,B3GALT2,TTLL9,AZGP1,BACH1,BID,DST,ARHGEF7,SCAPER,SGCE,CFAP410,CACNA1B,CACNA1E,CACNB4,HAP1,CAPN3,CBR1,ZNF501,CD86,ENTPD2,ARHGEF2,LRRFIP1,TIGD7,CLGN,DIS3L,SRSF11,CHM,JAM2,TAOK2,PPT2,DGCR9,CLTA,TJP2,SRP14-AS1,CNGA3,FHL5,CNN3,BTF3L4,IFFO1,AHCTF1,MYRIP,CHD1L,CPS1,FAM171B,MROH8,SOCS5,PDE4DIP,CNTNAP2,CMTM5,PHF14,CFAP61,NRSN1,FAM131B,CX3CR1,RIPOR2,HDAC4,AIF1L,PITPNC1,ARMCX2,MFAP3L,C2CD2L,SGSM2,WDR20,ZNF582-AS1,DMTF1,CASP8AP2,DRD1,PDCD6IP,TOM1,ABCC5,ABCC9,GOLT1B,E2F5,WDPCP,EDNRB,SYT15,FSD1L,MBNL2,TMEM35A,STARD3NL,OLIG2,ENO2,EPB41L1,COQ7,KCNMB2,GPHN,STX2,DENND4A,CDHR1,RCSD1,ADGRV1,GMPR2,CORO2B,CEP78,TOMM40L,FDFT1,KAT8,FER,FGF12,FGF13,FGR,CAMSAP1,FOXO3,SLC37A3,NOP56,AKAP3,DPYSL4,NBEA,TPK1,ATP2C1,DLL3,STAU2,ABLIM2,ZNF512,GAB1,ZNF559,DISC1,GATM,GCK,MSTN,GPR162,GFAP,GGTA1P,PPARGC1A,RUNDC3A,ZNF276,CRCP,TCERG1,RNPS1,STARD3,POLL,GNAO1,GNG3,GPM6A,LILRA2,NUDT21,PCLO,DIDO1,GRM2,GRM5,GRM7,FAM107A,SLC2A6,WIF1,NXPH3,BACH2,HMGB1,ZNF491,TLX1,CPT1C,OPALIN,SHISA6,SMAP1,ICA1,C5orf24,IGFBP1,USP54,SLC35G1,METTL21A,KCNJ11,KCNK1,STXBP5,KTN1,LAMP2,STMN1,INSYN2,LIMS1,NCOA7,PIK3AP1,MAPT,MATN2,MATN3,SYT9,LDLRAD3,TM6SF1,MPP2,DBNL,COMMD5,PTOV1,MTTP,MTR,MXI1,MYO6,MYO7A,NEXMIF,FXYD7,FXYD6,NEK1,NELL2,NEUROD1,NFE2L2,NRCAM,SMIM11A,NTRK2,NUCB2,OCRL,OGG1,PCDH9,PCMT1,PDGFRA,PFKFB2,SEMA5B,SNX10,NLE1,PLIN1,HMGCLL1,PNMA3,SDK2,MAGEL2,TNPO2,POU6F1,PTPA,PPP2R5C,PRKACB,PRKCB,PRKCZ,GRAMD1C,MASP1,VPS13C,PIGG,MTMR10,OCIAD1,PTPRD,FAM120C,PEX5,ZSCAN2,RALGDS,IQSEC3,MSANTD2,RDX,PRRT2,ARHGEF10L,RNASE1,NUDT11,RPRD1A,LGI2,DCUN1D2,TMLHE,ROBO1,RORB,ATP8B4,ATAT1,KCNIP2,NCBP3,FAM192A,SOX6,SCAF8,FAM102A,ASAP3,DZIP1,WDR37,LRRC55,SLC12A2,ELMO2,SLC22A4,NAXD,GKAP1,SORCS3,CDK5RAP2,SNAP25,FAIM2,SNRPN,UNC80,WDTC1,ZCCHC24,TSNAXIP1,SOX10,KDM3A,ENKUR,KIF1B,IQSEC2,TSPYL2,RAP1GAP2,C11orf87,TROVE2,POGZ,STOX1,MAPK8IP3,STX1A,KANK1,ARHGEF9,FNDC9,SYP,SLC37A2,VWA3A,SIN3B,ZEB1,DOCK9,PUM2,FRYL,CRB1,ITGB3BP,AP4E1,ENHO,ZFP91,TMPO,DAAM2,FAM124A,CSMD1,TPM2,C9orf85,RGMB,STXBP4,TRPM2,TSC1,HSPBP1,HEPACAM,BCL2L13,VAV2,VLDLR,BEST1,NSD2,GUSBP1,XPO1,ZNF24,NDRG4,TCEAL7,REEP1,DNALI1,LRP8,LINC02210,PCDH15,PPP1R3F,C12orf4,FAM13C,FZD3,UBE3B,KAT6A,CERS6,RNF170,ZNF30,JPH3" MicroRNA hsa-miR-19a-3p:TargetScan hsa-miR-19a-3p TargetScan 8.07E-132 4.53E-128 1.04E-130 9.61E-130 281 970 "ABR,NCKAP5,ACTN1,ARID1A,ADD3,GRAMD1B,KIAA1211,MTUS1,HECW2,KCTD16,OSBPL6,PCDH10,PITPNM2,CDC42BPA,LRCH2,MAP4K3,PHF12,PPFIA2,ANXA7,EPB41L5,MIER1,PPP4R4,ARHGAP5,CDK13,CAPRIN2,DDX3Y,ATP1A2,ATP2B2,NOL4,BCL7A,JAZF1,BSN,CALM1,KALRN,CAST,RUNX1T1,PRC1,CBFA2T2,EVI5L,CFL2,CHRNB2,PLAA,NMT2,CLTC,QKI,CNGA3,FHL5,CNR1,CNTFR,ARMC8,BTF3L4,ACBD5,HS3ST5,CLOCK,CRMP1,GDA,CS,LRIG1,MICAL2,CHD5,PLXNA4,APPL1,PHF14,RIMS2,PPP6R2,CCDC144A,DOCK4,ARHGAP32,GAPVD1,DCAF8,HDAC4,RASSF2,LONRF1,MAML1,IP6K1,GIT2,DNAL1,DBN1,MFAP3L,CEP170,MAGI2,KLHL3,G3BP2,DLX1,DSCAM,ARRDC4,DTNA,EBF1,EDNRB,HIPK3,MBNL2,ABI2,EGR3,PLXNC1,EIF4G2,EMX2,ERBB4,NCALD,ETV1,KATNAL1,EYA1,F3,ACSL4,PTK2B,SCML2,DLC1,MED12L,CAMSAP1,FOXF2,FLNC,NBEA,NPTN,ATP2C1,CELF1,GPR153,FUT9,DKK3,CAB39,NCKAP1,ARFIP1,GHR,CRCP,KDM2B,PRUNE2,CECR2,RAPGEF4,GRB10,KIF3A,RNF165,IL1RAPL1,FICD,KLF12,MIER3,HLF,ELOVL5,IGF1,C5orf24,IL6ST,DIPK1A,ITPKB,KCNA4,CDH20,KCNC2,KCNH1,KCNK2,KIT,ARHGAP12,LSAMP,MBNL1,CHIC1,MDM4,MEF2C,MID1,AFF1,MN1,MYCN,NEUROD1,NF1,NFIA,OCRL,KCNK10,PAX6,PDE3B,PDE4A,PFKFB3,PIK3C2A,CCSER2,PLCL1,PURG,LRP12,FAT3,POU3F2,PPARA,PPP2R5E,PRKACB,MAPK8,DIRAS2,PROX1,PSD,MTMR10,PTPRD,PTPRG,MARCH1,RAB5B,RAD51D,ATG16L1,RBBP8,RFX4,KLHL11,SEC61A2,CYB561D1,ROBO2,PRR5L,RIMKLA,RPS6KA2,CLIP1,RTN1,RXRA,SATB1,CSRNP3,ATXN1,ATXN7,SCN2A,SCN3A,SCN4B,SCN8A,ASIC4,HSPA4L,ITSN1,FAM102A,CPEB3,DOCK10,FNDC3A,R3HDM2,CNKSR2,EPN2,CCDC88A,NAPB,BTBD7,CPEB4,EPC1,RCOR3,LIMCH1,KIF13A,FAM126B,MYT1L,KIF1B,CDK19,NPAS3,MPRIP,RGL1,DIP2A,FAM168A,ACSBG1,ADAMTS17,C3orf70,PLCB1,ARC,ATP11A,ANKRD12,KAZN,CAMSAP2,FBXW11,EHBP1,DMXL2,ARHGEF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,HHIP,NACC2,DDHD1,HEY2,CSMD1,RBFOX2,RGMB,FAM155A,RICTOR,REEP1,DPYSL5,DHX33,PMEPA1,MAP3K12,CADM2,EVI5,NAV3,CAB39L,FZD3,PHTF2,FBXO36,ADAMTSL3,PIANP,FXR1,FRMD6,CBLN2" MicroRNA hsa-miR-19b-3p:TargetScan hsa-miR-19b-3p TargetScan 8.07E-132 4.53E-128 1.04E-130 9.61E-130 281 970 "ABR,NCKAP5,ACTN1,ARID1A,ADD3,GRAMD1B,KIAA1211,MTUS1,HECW2,KCTD16,OSBPL6,PCDH10,PITPNM2,CDC42BPA,LRCH2,MAP4K3,PHF12,PPFIA2,ANXA7,EPB41L5,MIER1,PPP4R4,ARHGAP5,CDK13,CAPRIN2,DDX3Y,ATP1A2,ATP2B2,NOL4,BCL7A,JAZF1,BSN,CALM1,KALRN,CAST,RUNX1T1,PRC1,CBFA2T2,EVI5L,CFL2,CHRNB2,PLAA,NMT2,CLTC,QKI,CNGA3,FHL5,CNR1,CNTFR,ARMC8,BTF3L4,ACBD5,HS3ST5,CLOCK,CRMP1,GDA,CS,LRIG1,MICAL2,CHD5,PLXNA4,APPL1,PHF14,RIMS2,PPP6R2,CCDC144A,DOCK4,ARHGAP32,GAPVD1,DCAF8,HDAC4,RASSF2,LONRF1,MAML1,IP6K1,GIT2,DNAL1,DBN1,MFAP3L,CEP170,MAGI2,KLHL3,G3BP2,DLX1,DSCAM,ARRDC4,DTNA,EBF1,EDNRB,HIPK3,MBNL2,ABI2,EGR3,PLXNC1,EIF4G2,EMX2,ERBB4,NCALD,ETV1,KATNAL1,EYA1,F3,ACSL4,PTK2B,SCML2,DLC1,MED12L,CAMSAP1,FOXF2,FLNC,NBEA,NPTN,ATP2C1,CELF1,GPR153,FUT9,DKK3,CAB39,NCKAP1,ARFIP1,GHR,CRCP,KDM2B,PRUNE2,CECR2,RAPGEF4,GRB10,KIF3A,RNF165,IL1RAPL1,FICD,KLF12,MIER3,HLF,ELOVL5,IGF1,C5orf24,IL6ST,DIPK1A,ITPKB,KCNA4,CDH20,KCNC2,KCNH1,KCNK2,KIT,ARHGAP12,LSAMP,MBNL1,CHIC1,MDM4,MEF2C,MID1,AFF1,MN1,MYCN,NEUROD1,NF1,NFIA,OCRL,KCNK10,PAX6,PDE3B,PDE4A,PFKFB3,PIK3C2A,CCSER2,PLCL1,PURG,LRP12,FAT3,POU3F2,PPARA,PPP2R5E,PRKACB,MAPK8,DIRAS2,PROX1,PSD,MTMR10,PTPRD,PTPRG,MARCH1,RAB5B,RAD51D,ATG16L1,RBBP8,RFX4,KLHL11,SEC61A2,CYB561D1,ROBO2,PRR5L,RIMKLA,RPS6KA2,CLIP1,RTN1,RXRA,SATB1,CSRNP3,ATXN1,ATXN7,SCN2A,SCN3A,SCN4B,SCN8A,ASIC4,HSPA4L,ITSN1,FAM102A,CPEB3,DOCK10,FNDC3A,R3HDM2,CNKSR2,EPN2,CCDC88A,NAPB,BTBD7,CPEB4,EPC1,RCOR3,LIMCH1,KIF13A,FAM126B,MYT1L,KIF1B,CDK19,NPAS3,MPRIP,RGL1,DIP2A,FAM168A,ACSBG1,ADAMTS17,C3orf70,PLCB1,ARC,ATP11A,ANKRD12,KAZN,CAMSAP2,FBXW11,EHBP1,DMXL2,ARHGEF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,HHIP,NACC2,DDHD1,HEY2,CSMD1,RBFOX2,RGMB,FAM155A,RICTOR,REEP1,DPYSL5,DHX33,PMEPA1,MAP3K12,CADM2,EVI5,NAV3,CAB39L,FZD3,PHTF2,FBXO36,ADAMTSL3,PIANP,FXR1,FRMD6,CBLN2" MicroRNA hsa-miR-3159:mirSVR_lowEffct hsa-miR-3159:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.09E-132 4.54E-128 1.04E-130 9.62E-130 342 1443 "CLK4,NCKAP5,ACTN2,CSMD3,ADARB2,TMEM132B,CCDC85A,TMCC3,ADD2,ADORA3,MTUS1,PCDH19,OSBPL1A,CC2D2A,AK2,TAOK1,CEP126,CARNS1,MAP4K3,USP28,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,APAF1,APOC1,AMER3,TNRC6C,APP,CDK10,TMEFF1,ARNTL,CDK13,ASTN1,ATP2B1,N4BP2L1,NRP2,SYNJ2,NIPA1,RAB29,CACNA2D1,CABP7,CALM1,PRC1,CBR1,KRIT1,SCARB1,DGKI,LOC730101,LARGE1,CCPG1,CHM,CHN1,JAM2,LHX2,KIAA1549L,CLCN4,CLTC,FAM19A5,HECTD1,CNN3,AKAP7,COL4A5,AKAP5,SLC4A7,AHCTF1,ACBD5,C2CD2,AKAP12,GDA,SNCAIP,ARHGEF10,CSNK1G3,NCAN,FAM169A,CTH,ARHGEF4,RIMS2,KIAA0408,MAML1,TOMM20,DNAL1,ARMCX4,DCT,C8orf34,SV2A,RABGAP1L,DLG2,RAB39B,DYNC1I1,NR1D2,CDON,PDCD6IP,GNE,ECM2,MAMLD1,DNAJB6,EDN1,EDNRA,KLHL5,EFNB3,RGS17,TMEM35A,EPB41L2,COQ7,DNAJC27,GMPR2,FAM198B,SH3YL1,EFEMP1,DLC1,FCGR3A,TOMM40L,FKTN,KIAA1109,FGF13,SYNCRIP,FLT1,ANKFY1,PDLIM5,FAM49B,NPTN,ZNF605,NRG3,FYN,GABRA2,HRASLS5,GABRG1,DENND2A,GAD1,C15orf41,IGSF5,SESN1,GK,TNRC6A,CBX1,INSM2,LUZP2,GNAO1,ADGRA3,GPD1,FUT10,GPR34,PCLO,GRIA4,GRIK4,PRDM5,GRM5,RASSF8,MAN1B1,ELOVL5,GABARAPL2,HNMT,AGFG1,HSP90AA1,SMAP1,HTR5A,ATCAY,C2orf72,SOWAHA,RBPJ,LRRCC1,LIX1,NME9,ITGAV,OLFM3,KCND1,KCNK3,CYP27C1,LAMP2,HECTD2,ARHGAP12,C2orf80,MAN2A2,MAT2A,MBNL1,TM6SF1,MDM4,MIA2,MID1,MMP16,ERICH3,SCG3,ZNF92,CTNNA3,LAYN,MYO7A,NAP1L3,NFE2L2,ALDH1L2,NKX2-2,NTRK2,GPR137C,CNTN3,PAX6,PDE4A,PDE4D,NALCN,ZNF655,CCSER2,ZFYVE21,RETREG1,RC3H2,SPATA6,PPARA,MED1,PPM1B,PPP3CB,RANBP3L,RASGEF1B,EPDR1,HYDIN,DIRAS2,SAMD9,PIGG,PTCH1,PTHLH,PTN,ZNF615,USP47,PLEKHB2,RAD51D,SH3TC2,NWD1,RAP1GDS1,OXR1,RASGRF1,RASGRF2,ZDHHC14,MSANTD2,REV3L,ERI2,GTDC1,PBRM1,RNASEL,RERGL,PCMTD2,NEK11,MCMBP,ACER3,LGR4,PTGR2,SYNDIG1,HUNK,ZNF331,MIR124-2HG,ATXN7,SCN7A,GALNT10,MRAS,FERMT1,FBXO11,ST6GAL1,CNKSR2,DZIP1,ABLIM3,ZNF365,RUFY2,LRRC55,SLC6A9,RAB3GAP1,ARHGEF40,TET1,CPEB4,INTS9,LIMCH1,MBD5,CABCOCO1,SCN3B,PDZD2,TRERF1,SOX11,GLT8D1,EMC1,HECW1,KDM4C,CDK19,NPAS3,TAB2,POGZ,SST,SSTR1,SS18,RGL1,SULF2,SEPT3,STXBP1,FGD4,JMJD6,SYT4,C12orf76,TACC1,CAMTA1,EXOC7,PDLIM2,ALG1,WWC1,AGTPBP1,KLHL4,VWC2,TPCN2,TRIM2,WDR7,AZIN2,DOCK9,OBSL1,ARHGEF12,CRB1,C18orf54,HHIP,ASXL3,ERCC6L2,KAT6B,CDK20,TPM3,C9orf85,PDSS1,ZMYND8,RFTN2,SLC13A3,XRCC4,SF1,ZIC1,ZNF711,ZNF24,LYPD6,ZNF189,PLPPR5,CSDE1,SCG2,SIGLEC10,PCDH15,NAV3,EPM2A,FZD3,CAMK1G,ADAMTSL3,MSRB3,NETO2,SOCS4,LAS1L,PRRT4" MicroRNA hsa-miR-15a-5p:TargetScan hsa-miR-15a-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-497-5p:TargetScan hsa-miR-497-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-195-5p:TargetScan hsa-miR-195-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-15b-5p:TargetScan hsa-miR-15b-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-424-5p:TargetScan hsa-miR-424-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-16-5p:TargetScan hsa-miR-16-5p TargetScan 8.31E-132 4.67E-128 1.06E-130 9.75E-130 296 1080 "ABCF1,ADCY5,GALNT13,AXIN2,PLEKHH1,ADORA2A,ADRB2,AP2A1,CASKIN1,ALAD,ARHGAP20,MARCH4,LTBP4,FAM135A,OGT,ARMC12,PPFIA2,CNIH2,CNTNAP1,APC,PPFIA3,APP,CASK,ARHGAP5,ARHGDIA,DDX3Y,ATP2B2,BCL2L2,BCL7A,DCAF5,NRP2,KSR1,CDK5R1,FUBP1,MTMR3,CACNA1I,LDLRAD4,BTRC,FOXK1,CA8,CACNA1E,DDR1,CACNA2D1,LURAP1,CALM1,CAST,MAP7,RUNX1T1,NFS1,FMNL3,AIFM1,CDC25B,CDC27,DLGAP2,KMT2C,PPT2,CLCN3,CLCN4,QKI,HECTD1,ARMC8,BAG4,SEC31B,CLOCK,AKAP12,RNF14,NCOR2,AATK,CSF1,LRIG1,CHD5,PLXNA4,PITPNM3,ERC2,MYADM,DCAF8,PHF19,KIAA0513,RIMS3,KIAA0586,KCTD8,IST1,IP6K1,CTIF,ARMCX2,ELMSAN1,MYEF2,CNIH3,DYNC1I1,CPEB2,DMTF1,FAM57B,DRP2,PDCD6IP,ARRDC4,GOLT1B,EDNRA,HIPK3,SEMA3D,FRY,RBM12,EBI3,MBNL2,ABI2,PLXNC1,PLEKHA1,EN2,EPB41L1,ANKRD13B,RAB9B,DENND4A,CEP85L,ETV1,KATNAL1,EYA1,EZH1,NRN1,ACSL4,FGF1,FGFR1,CAMSAP1,HPCAL4,CINP,PDLIM5,ARFGAP2,GPR153,NSG1,GABBR1,CAB39,ARPP21,SALL3,NCKAP1,PCDH17,GHR,RAB30,OS9,FERMT2,ADAP1,GRB10,RAPGEF1,RFFL,ADAMTS13,GRIN1,GRM7,IL1RAPL1,FICD,RASSF8,HAS2,NCKAP1L,DDX19B,BACH2,HPSE2,HMGCR,HTR2A,MSL1,IDH3A,C2orf72,IGF1,NKD1,RBPJ,KCNC2,KIF5A,KIF5C,KPNA5,LIMS1,NAT8L,MAP4,AQP11,MBD1,CHIC1,LRP1B,PPM1L,MN1,GIT1,RSPO2,MYO5A,NDP,NF1,OTOGL,NOS1,HCN1,OCRL,OMG,KCNK10,PCMT1,PCSK5,PDE3B,CAMKV,PIK3C2A,ANLN,PIK3R1,PLCD1,PLXNB1,PSAT1,EPB41L4B,FAT3,NXPH1,POU3F2,FSD1,MED1,LRRN3,PPP2R5C,PRKAB2,RASGEF1B,PKIA,MAPK8,RELN,CNNM2,PTCH1,PTHLH,PTPRD,PEX5,PID1,FAT4,RBBP6,BSDC1,RET,RFX3,C12orf49,ARMC5,GSTCD,CYB561D1,RORB,FBXW7,SALL1,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,MRAS,HSPA4L,PUF60,KIF21A,PPM1E,CPEB3,CHD9,CNKSR2,NLGN1,DZIP1,FAM81A,ELMO2,EPC1,RCOR3,MYT1L,NMNAT2,LHFPL4,ARHGAP26,KIF1B,NPAS3,NFASC,LHPP,ATP10B,COLGALT2,KANK1,GSE1,ACSBG1,PRRC2C,MMS19,MCF2L,CLASP1,FAM189A1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,DICER1,ARL10,CBX5,CSMD1,NR2C2,CADM1,AMOT,KLC2,RICTOR,EML6,RGMA,CSDE1,EVI5,GDPD5,LMAN2L,CIAPIN1,PPP1R3F,KCNAB1,PLSCR4,RTN4,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-32:mirSVR_highEffct hsa-miR-32:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.02E-132 5.07E-128 1.15E-130 1.06E-129 306 1156 "SYN3,RBM10,NCKAP5,CSMD2,CSMD3,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,SLC24A4,TXNDC16,ALCAM,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,MIER1,MARCH3,ASPH,NCOA1,RASL11B,DDX3Y,ATP2A2,MTMR9,B3GALT2,ADAM23,ADGRB3,MPDZ,BCHE,HCN2,CDK5R1,SYNJ1,ARHGEF7,CACNA1I,OSGIN2,KALRN,CAMK2A,LDB2,MTMR7,AIFM1,CDC27,CDH10,L3MBTL4,SOCS6,CHM,NRXN3,HECTD1,NIPBL,TMEM155,CNRIP1,HS3ST5,FAM171B,CREM,CRHBP,SLC32A1,LRIG1,ATRNL1,SOCS5,SLITRK5,ERC2,APPL1,PPP6R2,USP6NL,EDRF1,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,G3BP2,WDR20,CDON,CPEB2,PDCD6IP,ARRDC4,ABCC5,DNM1L,E2F5,AASDH,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,DENND4A,TMEM74,FDFT1,KIAA1109,POLK,FOXF2,ATP13A4,SLC37A3,TACC2,UFM1,PDLIM5,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,GABRA1,CHL1,ARPP21,IQGAP2,GAP43,ZNF559,DISC1,GHR,GLYR1,PCDH11X,ZNF638,FERMT2,CNDP1,GPD2,GPM6A,LILRA1,LPAR4,GPR37,TPPP,GRIA1,DIDO1,RFFL,GRM1,GRM7,FAM19A2,HAS2,ZHX1,MIER3,SCRG1,HNMT,MSL1,USP54,SLC6A17,ITGAV,C2CD4C,KIT,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,LRP1B,ERICH3,ZNF680,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,DNHD1,SMIM11A,CLDN11,P2RX7,GPR137C,SNTG1,PDE1A,PDE4D,GPR85,GNG2,PIK3R1,CCSER2,SNX10,ZFYVE21,PLCL1,JAKMIP1,PLP1,PDZRN4,TRHDE,STRN3,SCHIP1,ING3,MED1,PPP2R5E,CEP41,RAB39A,SNRK,PTPRD,EML5,PTPRO,PEX5,TMEM255A,PLEKHB2,ENOX1,RASGRF2,BSDC1,RDX,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RPE,RPE65,RPL15,FBXW7,LGR4,ABCA11P,AP1AR,SALL1,SATB1,SCN3A,FAM19A1,FNIP1,SUPT20H,KIF21A,CPEB3,MYO18A,CHD9,SLITRK3,CNKSR2,ZNF430,RAB3GAP1,SLC12A2,SLC22A4,TET1,CPEB4,DMRTC1,CDK5RAP2,TTC17,LIMCH1,PALLD,SON,PDZD2,SOX11,MYCBP2,TEX2,KIF1B,NPAS3,PBLD,CLASP2,ITPRID2,EPB41L3,ELOVL4,RGL1,AJAP1,FGD4,ZFR2,SYN2,SYPL1,SYT1,SYT4,TAC1,CAMTA1,FBXW11,ANO4,ATMIN,ZEB1,TCF12,SYNE1,DOCK9,SIK3,FAM200B,HHIP,THBS4,ERCC6L2,KCTD2,TPM4,SYNPO2,TRIO,ZMYND8,SGK3,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,TRIM9,FMN2,ZNF142,ZSCAN26,CA10,EMSY,MFF,LRP8,EVI5,RNF103,ADAMTS9,NAV3,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,NETO2,SLC4A10" MicroRNA hsa-miR-143*:mirSVR_lowEffct hsa-miR-143*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-131 6.42E-128 1.45E-130 1.34E-129 359 1588 "ABR,SYS1,TMCC3,GALNT13,PWWP2A,KIAA1211,AP1B1,MTUS1,ALCAM,ANK2,ANK3,USP28,CNIH2,SUGT1P4-STRA6LP-CCDC180,APBB2,EPB41L5,PLA2G4C,MARK4,RASL11B,ASTN1,INSYN2B,ALDH4A1,ADAM23,ADAM15,ADGRB2,BARD1,SEC11C,BCL7A,CDK5R1,SYNJ1,ARHGEF7,FUBP1,SCAPER,MTMR2,CACNA1G,OSGIN2,BSN,BTRC,CACNA1D,CACNB2,CALB1,CAMK2B,TRIM41,VSTM2A,CH25H,SPAG9,SLC16A4,ARHGEF1,SYNGR3,CDK11B,CDC42,IGFN1,CACNA2D2,NPIPA1,CHM,COG1,CLTC,TJP2,SRP14-AS1,HECTD1,NIPBL,SLC25A27,TBPL1,MYRIP,CNRIP1,ZNF385A,CPS1,SEC31B,CDC42BPB,ATRNL1,DZIP3,APPL1,UBXN2A,PLCXD3,CTNND1,NRSN1,ST18,CX3CR1,DOCK4,RIPOR2,TOX,EARS2,MATR3,IP6K1,CTIF,CEP170,TMEM130,GSDME,GUCD1,SNAP91,NTM,SGSM2,G3BP2,DLX1,DMD,SLC29A4,CDON,DNM2,ACOT8,ABI1,RCAN1,DTNA,ABCC5,DNM1L,AASDH,EBF1,EDN1,HIPK3,FSD1L,FAM13A,EBI3,RASA4,C8orf37,EMX2,EPB41L1,SEZ6,STX2,IGSF6,EFS,F5,CLVS1,TMEM132C,DLC1,ST3GAL6,FCGRT,CAMSAP1,SUCO,HPCAL4,FOXF2,SYNCRIP,FLNC,FLT1,SGIP1,PDLIM5,ATP2C1,GPR153,MPP6,MEGF11,ZNF44,GABRA5,SALL3,C15orf41,DNER,ALDH1L1,AHDC1,MALT1,HPGDS,GLRB,PCDH11X,ZNF638,GNG4,CNDP1,GPR37,TMEM121B,CNTRL,TPPP,GRIA2,ATE1,TMEM25,AP4S1,GYG1,FAM222A,RASSF8,ARHGAP19,HTR5A,LIX1,ITPKB,KIF5A,KIT,A1BG-AS1,KLC1,INSYN2,LIMS1,SYTL4,HECTD2,MAN2A2,ZFYVE27,MARK1,MBNL1,MDFI,PPM1L,ZNF680,ADAM22,MT1M,MT3,MYT1,NACA,NAP1L2,NBL1,ZC3H12B,NEUROD1,NFYA,CNOT4,NPTX1,NTRK2,OLR1,OMG,ZNF827,DPY19L2P2,PCDH9,PDE4D,PIRT,ENPP2,GPR85,ABCB1,PIK3CD,PLIN1,PLXNB3,PNMA3,FAT3,POU6F1,PPP1R1A,PPP3CA,PPP3CB,RASGEF1B,PRKACB,PRKCB,PRKCG,PRKCZ,PLPPR1,MTMR10,ELOVL2,SPDL1,PTPN13,PTPRD,PTPRZ1,TMEM231,PPP2R3C,RALGDS,RASGRF2,RDX,SLC6A15,CRTAC1,GTDC1,ZDHHC4,RGS12,NUDT11,PBRM1,ROBO2,CCDC102B,TMEM100,NEK11,GLDN,SGSM1,ACER3,STK32B,CNTNAP3,ABCA11P,WLS,RTN1,ZNF331,TRAPPC13,SEMA6D,DRAXIN,FAM19A1,ELMOD1,SOX6,TRIM46,GALNT10,MRAS,SCAF8,PPM1E,CHD9,R3HDM2,SLITRK3,NLGN1,ST3GAL3,NUBPL,WDR37,SLA,PPP4R3A,RAB3GAP1,ARHGEF40,ATF7IP,RIMS1,MAPKBP1,MBD5,TMCC1,MYO16,FAM219A,PDZD2,NMNAT2,TEX2,ZNF423,KIF1B,CDK19,ZBTB43,NFASC,LHPP,PBLD,CAMTA2,EPB41L3,NKAIN2,SSPO,RGL1,SULF2,FGD4,C3orf70,SYT1,SLC37A2,DDHD2,TAF6,MLST8,ADGRL3,AGTPBP1,MGRN1,VWA3A,TCF4,DMXL2,ZFP90,TCF7,ZEB1,SZT2,WDR7,PUM2,RNF216P1,PMS2CL,C18orf54,AP4E1,ZNF106,SLC44A1,ARL10,TMOD1,TMPO,KAT6B,TP53BP2,CHST5,TSC1,SSBP2,TUB,RPRM,SLAIN1,FLRT1,USP1,MGAT5B,BEST1,VSNL1,CLIP2,RICTOR,GUSBP1,SLC47A2,AGMO,TCEAL7,TMEM237,AMZ1,FTSJ1,ZNF213,ZFAND5,UPF3A,CSDE1,STOX2,NAV2,MPPE1,DOCK8,JMJD1C,ZNF248,KLHDC1,GAN,FAM198A" MicroRNA hsa-miR-3172:mirSVR_lowEffct hsa-miR-3172:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-131 7.57E-128 1.71E-130 1.57E-129 384 1808 "TTYH1,EMILIN3,ADARB2,ADD2,ESYT2,SLC44A5,KLHL13,RTL9,ALCAM,DOC2A,ANK2,CCDC146,USP28,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,APP,SHTN1,AQP4,AQP6,PPP4R4,ZFYVE28,CDK13,ASCL1,MARK4,DACT3,NUMB,EIF4G3,STX16,SLC2A11,RNF182,ALDH7A1,ADGRB1,SNAI3-AS1,ADGRB3,BCHE,RGS11,BCL2L2,NRP2,KSR1,BMP7,ARHGEF7,BTK,BSN,RAB29,BTRC,CA8,CACNB4,CALM1,KALRN,VXN,CAST,RUNX1T1,AIFM1,DGKI,LRBA,SEPT7,CDC27,ZBED1,CDC42,LGI1,DIS3L,EPS15L1,KIAA1549L,CLCN4,NRXN2,TPP1,NMT2,DNAJB5,SULT4A1,IGLON5,ARHGEF6,CNR1,COL4A5,SUMF2,LETMD1,SLC4A8,ABI3BP,ENTPD4,SH2B1,AKAP12,ANKRD44,CLIP3,ABCG1,TENM4,RGS6,ARHGEF10,MICAL2,PDE4DIP,CMTM5,GREB1,NRSN1,RIMS2,GPSM1,DOCK4,KATNAL2,TCAF1,CENPL,TBC1D5,MATR3,MAML1,BRINP1,ZBTB24,HEPH,ELMO1,KIAA0753,COPS7A,ZC3H11A,POM121,RHOBTB1,PLPPR4,WDR20,KIF19,ARNT2,CHRDL1,DLG3,HS3ST4,DMTF1,SLC25A18,ATN1,GNE,DTNB,MAMLD1,DYRK1A,SNX29,FCF1,CNNM1,SIDT2,ELAVL3,STARD3NL,EN2,EPHB1,MRPL37,TLR7,RASL12,SIRPB1,ABCA8,WAC,CHST15,GORAB,GTF2IRD2,FGF11,FGF13,CAMSAP1,POLK,UBE2E3,PCYOX1,FLT1,NOP56,FLYWCH1,EFCAB2,PDLIM5,FAM49B,STAMBP,ARFGAP2,ATP2C1,ZNF605,DACH2,ABLIM2,GABRA3,GAD2,HBS1L,FAM120B,ZNF234,DISC1,MYOZ2,GCK,GCNT2,SULT1C4,ADAM28,MALT1,ZNF276,SPIN1,GLS,KDM2B,KCNMB4,GNAS,ZNF782,EML4,GRB10,GRIA2,RFFL,ADAMTS13,GRIN2D,GRM1,GRM7,BVES,LINC01551,RABL2A,RNFT2,ADAMTS6,SLC2A6,MUM1,MAEL,ZHX1,GPR45,ARHGAP19,HMGB1,HNF4G,TLX1,ATCAY,LINC00667,ZNF546,C5orf24,USP54,SCIN,ZNF385B,ITPKB,METTL21A,KCNJ5,GATD1,KIF5A,CYP27C1,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,ARHGAP12,NCOA7,GPR155,MAOB,MBNL1,CHST6,SCAMP5,POC1B,XRRA1,MMP16,HS6ST3,RTL5,NDUFA5,NF1,NPTX1,NRCAM,NUMA1,OPHN1,LOC100128398,PAK3,PDYN,OLA1,CDK14,DUSP26,GPSM2,ANKRD16,PMP2,ING3,SPATA6,PACSIN1,TNPO2,POLR2F,PPP2R2B,CRLS1,PPP3CB,RASGEF1B,SLC26A11,CNNM2,SYTL2,GON4L,PTPRG,FAM120C,ZNF615,PPP2R3C,PID1,CCDC40,PLEKHB2,SH3TC2,RFX4,ZDHHC4,UBR7,RIC8B,CCDC82,ALG9,PNMA8A,ROBO1,ROBO2,SNX22,ATP8B4,SGSM1,PTGR2,MAPK12,ATXN2,SCN2B,PRCD,ASIC4,ELMOD1,SEC14L1,GALNT10,ITSN1,KIF16B,FNDC3A,SEC31A,NUBPL,PEX26,BTBD3,KANSL3,SLC8A3,SIRT2,ATF7IP,SLC22A4,MAST1,CDK5RAP2,SNRPN,SCN3B,SON,WDTC1,SOX1,ZSWIM8,EMC1,HECW1,PEG10,ZBTB43,C11orf87,ATP10B,CLASP2,ITPRID2,SSTR2,INKA2,CEP68,STAC2,ADHFE1,PHLDB1,KANK1,GSE1,KLHL7,ARHGEF9,C3orf70,ANKRD28,ROBO3,EXOC7,TAL1,KLHL4,ANO4,VWA3A,DMXL2,ZFP90,TRIM2,WDR7,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,SIK3,ZFPM2,CRB1,FBXL16,TIAM1,TIE1,DDHD1,PRRT1,CDK20,WBP2,CHST5,ZNF346,METTL3,TRPC1,PPIL6,SGK3,SLC35A4,FRRS1L,MEAF6,VIPR2,VSNL1,ZIC2,ZIC3,TCEAL7,ZBTB16,ANKS1B,LAMP5,PRDM2,PRDM10,ADAMTS9,SLC17A7,LINC00632,WIPF2,FZD3,HNRNPA3,IFT88,NETO1,ST8SIA2" MicroRNA hsa-miR-920:mirSVR_lowEffct hsa-miR-920:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.73E-131 9.71E-128 2.18E-130 2.01E-129 397 1927 "VWA5B2,ABAT,ASIC1,ACHE,AS3MT,NBAT1,SYS1,ACTN1,CSMD2,GPRIN1,NDRG3,KLHL32,SLITRK1,ADCY6,ADD1,SORCS1,GRAMD1B,PTCHD1,AP2A2,AP1B1,KIAA1324,C1QTNF1,PCDH10,LRFN1,ZFAT,OGT,FGD2,USP28,PPFIA4,SUGT1P4-STRA6LP-CCDC180,APAF1,SHTN1,AQP6,SLC7A14,SFMBT2,SEMA4G,PRX,PCDHGB4,DPY19L3,ADAM15,ADGRB1,BBS2,DNAJC27-AS1,KSR1,CASTOR3,AP1M1,CFAP410,CA8,CACNA1D,LURAP1,CALB2,HAP1,CAMK2A,BRSK2,ISPD,ZNF501,SLC16A4,CBFA2T2,DGKI,SRSF11,CHRM1,PLEKHB1,CASC2,B4GALT6,TAOK2,PPT2,FBXO7,MAP4K4,ARMC8,CABP1,SUMF2,TOGARAM2,MFSD4A,CHD1L,ANKRD44,CS,SNCAIP,CSF1R,SUSD5,VAC14-AS1,PLXNA4,KIAA0040,GREB1,NRSN1,MYADM,KATNAL2,HDAC4,PHF19,MAML1,DGKB,DGKG,SCRN1,ZNF804A,HP1BP3,SGSM2,DLG2,SLC12A6,DPH1,RCAN1,DNAJB6,SNX29,FAM135B,FCF1,SIDT2,CACNG7,RBM12,YAF2,APH1A,ABI2,TMEM132E,AASS,SORBS3,COPS4,SRPK3,C3orf18,EN2,EPB41,EPB41L1,EPB41L2,COQ7,EPHB1,STX2,VPS26C,RASL12,SIRPB1,CD320,MRVI1,F3,PTK2B,RACK1,KAT8,GTF2IRD2,SPSB4,POLK,SUCO,FOXM1,ANKFY1,EFCAB2,SORBS1,AK8,PDLIM5,USP21,TRIM16,NSG2,CELF1,NSG1,STAU2,ADGRA1,AP4B1,ABLIM2,ZNF512,GAB1,ARPP21,GHDC,CPLX2,GCK,ALDH1L1,SRCAP,KIRREL3,TTBK1,HPGDS,RAB30,KDM2B,POLL,LILRB4,GPD1,GPD2,GPM6A,ATF7,FUT10,GRB10,GRIA2,GRIK1,SPACA9,SERP2,BTN2A1,GSTM5,KAT7,GSTT2,ZBTB49,AP4S1,RABL2A,FAM107A,RNFT2,ATOH8,ZHX1,PTGDR2,ATXN2L,ARHGAP36,ZDHHC15,HSD17B1,SHISA6,C2orf72,LRRC25,INPP5B,ZNF385B,KCNA6,KCNJ5,KCNJ9,GATD1,CREG2,KLRC2,A1BG-AS1,KLC1,L1CAM,TTYH2,STMN1,SFXN5,VWA5A,MAN2A2,MAP4,MDM4,DBNL,SAMD5,MYO6,MYO7A,MYT1,FXYD7,NBL1,SFR1,NELL1,NFE2L2,NNAT,NOVA1,SLC11A2,NRGN,CLDN11,ZNF827,PCDHGC3,CDK18,PIRT,NLGN3,PLCB2,ST8SIA5,FTO,PLIN1,FXYD1,PLXNB3,PRIMPOL,ANKRD16,C19orf57,PPARA,TATDN3,NKAIN4,PRKCZ,MAPK3,WBP1L,PIGG,PTCH1,PXK,TMEM260,STK32A,FAM120C,ZSCAN2,SLC25A48,ZNF793,SUSD4,RDX,GAL3ST4,TRIM68,PRRT2,RGS3,RPRD1A,MYH14,GSTCD,YY1AP1,SNX22,KIAA0895L,ATAT1,ZNF568,RXRG,ZNF331,FAM182A,MAPK12,CSRNP3,HOGA1,LRRTM4,PRCD,ASIC4,SOX6,TRIM46,CASC3,NTNG1,R3HDM2,SYBU,ST3GAL3,CTXN2,ST8SIA1,SLA,SLC1A3,RPH3A,SLC2A5,DHX30,RUFY2,KANSL3,SLC6A7,SLC8A2,SIRT2,SLC11A1,SMARCC2,MAPKBP1,SNCA,MBD5,SNRPN,RBM34,DOP1A,WDTC1,BDP1,TSNAXIP1,SOX10,FNBP1,SOX15,SP2,KDM4C,IDI2-AS1,PEG10,SPTAN1,CDK19,LMO3,FCHO1,ZSCAN29,APOM,RHBDL3,ARHGEF9,ADAMTS17,SYN1,FAM208A,ALG1,IQCE,FBXW11,MGRN1,VWA3A,NEU4,TCF7,TCF7L2,ZEB1,TPCN2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,NAT16,PCDHGA1,TMEM151B,SIK3,RNF216P1,ATP13A2,DICER1-AS1,TIAM1,TIE1,TMEM9,TLL2,TLR4,ERCC6L2,FAM124A,PIK3R5,TPM3,IL34,WBP2,TRH,TRPM2,TRPS1,TTTY15,SLC35A4,OSBP2,FLRT1,PLEKHH2,ZNF709,VIPR2,TBC1D15,CLIP2,KLC2,ZNF70,LYPD6,TMEM198,SLC30A4,DNALI1,SLC38A1,URM1,TRIM16L,PDSS2,RNF170,PIANP,NETO1,AP3B2,LAS1L,FAM198A" MicroRNA hsa-miR-1224-3p:mirSVR_lowEffct hsa-miR-1224-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-131 1.00E-127 2.25E-130 2.07E-129 368 1668 "DPF1,SDE2,DGCR6,ASPHD1,ASIC2,ASIC1,C3orf14,SLC25A25,KLHL32,GALNT16,ADCY6,GALNT13,ERMN,PLEKHH1,ADORA3,AP1B1,TBC1D14,TAOK1,ALCAM,MARCH4,SYT13,KIF6,ANK2,USP28,PPFIA4,SUGT1P4-STRA6LP-CCDC180,SHTN1,AQP6,SEMA4G,CASK,SPTBN4,RGS20,PLA2G4C,DNAH17,MARK4,CAPRIN2,CHID1,STX16,SLC2A11,ADAM15,BBS2,CFLAR,LINC00906,CACNA1I,CACNA1G,GPC2,CDK5R2,CA4,CALB2,NGB,TRIM41,PRC1,KYAT1,KRIT1,METTL6,P2RX6,SCARB1,AP4M1,CDC25B,CDH2,ZMYM4,LRRFIP1,CHRM1,TAOK2,ARHGAP22,TPP1,MAP4K4,TMEM155,SUMF2,LETMD1,IFFO1,ZFP28,SH2B1,HAPLN1,CRY2,ANKRD44,ABCG1,ARHGEF10,MICAL2,SUSD5,PDE4DIP,CST3,PLXNA4,GREB1,CTNND1,USP6NL,ECE2,KIAA0408,MYADM,GAPVD1,RIPOR2,DCAF8,CENPL,IST1,TOMM20,AIF1L,DNAJC6,ZEB2,ZBTB24,COPS7A,CEP170,POM121,PLPPR4,SV2B,AK5,SGSM2,G3BP2,ARNT2,DLG3,RAB39B,CDON,DRD1,DSCAM,EBF1,SNX29,EDNRB,SIDT2,YAF2,EFNB3,APH1A,MRO,TMEM132E,ELAVL4,EIF1,EN2,SEZ6,EPHB1,RABEPK,ERBB2,EXTL1,SIRPB1,HSPA12B,F5,FABP7,PTK2B,FCGR3A,ZSCAN30,KAT8,PPP1R1B,ZNF589,SLC9B2,GTF2IRD2,POLR1B,FHL1,POLK,FOXF2,IP6K2,RGPD5,IQCG,FOXM1,NOP56,POMT1,NPTN,CAMKK2,ZNF605,MSANTD4,HHIPL1,SDCBP2,MEGF11,MEGF10,DENND2A,JPH4,DISC1,TUBGCP4,ADAM28,GHR,LYVE1,RND1,OS9,GPM6B,STON1,GRIA1,GRIA2,PLCD4,ADAMTS13,SERP2,RNF165,MFSD2A,LINC01551,AP4S1,ATOH8,TMEM179,RASSF8,NCKAP1L,AGBL5,HSD17B1,IRF8,LRRC25,RBPJ,PLD5,SCIN,INPP5B,SLC35G1,KCNB1,KCND3,KCNH2,KCNJ10,KCNJ11,KCNK3,A1BG-AS1,CYP27C1,STMN1,SMAD1,LOC100128239,MAT2A,MMP16,MOV10,MSR1,MT3,MYBPC1,MYO7A,MYO9A,FXYD6,NHLH1,DNHD1,SLC11A2,NTRK2,CLDN11,ZDHHC22,SNTG1,PBX1,PDE2A,PIRT,PDGFRA,HERC2P3,GDAP1L1,ZNF426,MTRF1L,RC3H2,ING3,RETREG2,EPB41L4B,PACSIN1,FSD1,MINDY2,PPP1R1A,PPP3CC,MAPK4,CYBC1,TMEM104,PTPRE,FAM120C,TMEM231,CCDC40,ZNF793,ATG16L1,RAP1GAP,TRIM68,RFX4,RNASE1,GSTCD,CYB561D1,CCDC102B,EPHA10,ZC3H14,MCMBP,ADAL,KCNIP2,RTN1,TMEM156,MAPK12,ATXN7,TRIM46,CASC3,ASRGL1,MRAS,COPZ1,KIF21A,FERMT1,MYO18A,NUBPL,CLSTN1,SLC1A6,SLC1A7,PEX26,BTBD3,LRRC55,SLC6A7,RAB3GAP1,NAPB,SCMH1,NAXD,SMARCE1,RCOR3,LIMCH1,RIMS1,SNRPN,MYO16,FAM219A,TNIK,CLUAP1,KIF1B,ATP10B,POGZ,SMOC1,ZC4H2,ZSCAN29,SEPT8,CEP68,KANK1,SEPT3,SYT11,VAMP1,RHBDL3,NUDT10,TMEM150C,SYN2,SYP,SYPL1,SLC37A2,ASTN2,ATP11A,TACC1,PDLIM2,UNC5D,VWA3A,WSCD1,KIAA0930,SZT2,AZIN2,SLC19A3,TNS2,HIF3A,CYB561A3,C18orf54,THRA,TNR,PIK3R5,TP53BP1,TPD52,PRMT8,NEIL2,FNDC5,TTTY15,FAM155A,UBTF,WIPF1,NSD2,NPDC1,RICTOR,GUSBP1,ETNPPL,LGI4,ZFP41,AGMO,ZNF74,PLPP4,SLC26A10,CRB2,SPHK2,ZBTB16,SPIRE1,SMARCAD1,SLC30A4,MAP3K12,SLC38A1,STMN4,SIGLEC10,WIPF2,PLSCR4,GOPC,DOCK8,CASC15,JMJD1C,ZNF248,TIGD6,IFT88,RNF146" MicroRNA hsa-miR-559:PITA hsa-miR-559:PITA_TOP PITA 2.77E-131 1.56E-127 3.49E-130 3.21E-129 263 848 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,ETV1,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,BTBD7,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-1261:mirSVR_lowEffct hsa-miR-1261:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.16E-131 2.34E-127 5.22E-130 4.81E-129 332 1368 "RALGAPA1,TTYH1,ABCF1,CSMD3,FMNL2,SLITRK1,GALNT13,CDC7,ADORA3,PTCHD1,ADRA1D,BEND6,TBC1D14,TAOK1,SMIM17,SPOP,ALCAM,BCAR3,ABCD2,DPP10,ANK3,PHF12,PPFIA1,APBB2,GPAM,CACHD1,TNRC6C,AQP4,ARNTL,ATM,ATP2B1,ATP2B2,MTMR9,SEC11C,NRP2,CFLAR,SYNJ2,SCAPER,MTMR2,CA8,THSD7A,RUNX1T1,METTL6,MTMR7,ARHGEF1,LOC730101,CHGA,RAB3C,IGFBP7-AS1,KIAA1549L,ABCG2,DNAJB5,SRP14-AS1,MAP4K4,CNN3,IQCK,COL4A5,SLC4A7,COX4I1,TOGARAM2,C2CD2,ENTPD4,CREB5,CS,SEC24C,CSNK1E,ATRNL1,NCAN,SOCS5,VAC14-AS1,PHACTR3,KIAA0040,CTH,NRSN1,RUBCN,CYBB,KIAA0408,HDAC9,HDAC4,EARS2,DBI,GIT2,HEPH,TIAM2,CEP170,BLOC1S6,LYPD1,RHOBTB1,G3BP2,RAB39B,NR1D2,DOCK2,DMTF1,DPP6,DRP2,ARRDC4,E2F5,EBF1,EDIL3,EDNRA,RASGRP1,EFNB3,FAM13A,PHF20L1,MRO,EGR3,ELN,EML1,ERBB4,DENND4A,ETV1,RTN3,TUBA1B,ATP8A1,FCGR3A,TOMM40L,FER,MED12L,OLFM1,FGF13,FGF14,FGFR1,SUCO,CAP2,PCYOX1,SYNCRIP,FOXO3,FLT1,ANKFY1,NELFCD,TPK1,DACH2,AP4B1,PHYHIPL,GABBR1,GABRA1,GABRA2,HRASLS5,CHL1,ILDR2,ARPP21,GAP43,DISC1,KIAA1841,NEU3,ALDH1L1,SPIN1,PSRC1,TDRKH,GPR12,STON1,LPAR4,GRIK1,GRM7,BTN2A1,GSN,RNF165,PTPN5,GSTM5,BVES,LINC01551,FAM107A,MAP4K5,MUM1,RASSF8,HPS5,HLF,HMGCL,HNF4G,ZNF491,ZDHHC15,IRF8,IGF1,LRRCC1,RIPPLY2,OLFM3,KCNH2,KCNJ10,KLRC2,CYP27C1,STMN1,PAXBP1,MAN2A2,LYPLAL1,MBNL1,CHIC1,LDLRAD3,LRP1B,SHC3,MEF2C,MITF,CPNE9,CTNNA3,P2RY13,ZC3H12B,NEK1,DNHD1,LRIT2,NTRK3,IGSF11,ZNF713,KCNK10,PBX1,PCDH9,PDE3B,GPR85,BEST3,PFKFB2,A2ML1,CCSER2,RETREG1,FTO,SLC25A23,PURG,LRP12,PRRX1,SH3KBP1,POU3F2,PPARA,PPM1B,CCDC144B,PPP2R2C,CRLS1,PPP2R5C,PPP2R5E,PKIA,SIDT1,MDGA2,MTMR10,SPDL1,PTPN13,PTPRB,C1orf109,TUG1,PID1,CEP97,TMEM255A,RAP1GDS1,ZNF493,RASGRF2,DBX2,FEZF2,RBBP6,GTDC1,FIGN,RIC8B,SETD5,ROBO2,CCDC25,YY1AP1,ATP8B4,RPS6KA2,MAP6D1,SYNDIG1,ZNF568,S100B,SALL1,ATXN1,ATXN2,SCP2,TNFRSF19,MRAS,COPZ1,KIF21A,FERMT1,MAGI3,FBXO11,FHOD3,ZNF365,DHX30,FAM214B,SLC6A11,SLC20A2,GKAP1,ANKRD36,LIMCH1,SNCA,MBD5,SNRPN,MYO16,UNC80,USP33,DOP1A,SON,TRERF1,SP2,HECW1,COLGALT2,SMOC1,KANK1,ARHGEF9,VPS13A,CNTN2,KIAA1107,EHBP1,DMXL2,RPGRIP1L,TNS2,SIK3,DICER1-AS1,HHIP,TIAM1,ERCC6L2,HEY2,NPL,RGMB,ELP5,TRPC1,TRPS1,FRRS1L,CCDC14,RICTOR,XPO1,ZIC1,MKRN3,LYPD6,POLR3H,AMZ1,PRDM8,RNF103,CIAPIN1,GAL3ST3,KCNAB1,FIP1L1,WNK3,WNK2,SLC17A6,FAM13C,CERS6,SSPN,SLC4A10,CPNE4" MicroRNA hsa-miR-556-5p:mirSVR_lowEffct hsa-miR-556-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.21E-131 2.36E-127 5.26E-130 4.85E-129 351 1526 "SERPINA3,DGCR6,SYS1,GPRIN1,TMEM132B,AXIN2,GRAMD1B,OLMALINC,KIAA1324,PLA2G6,ALCAM,PPFIA1,FAM131A,VAT1L,SHTN1,MIER1,IGDCC4,CDK13,PDE8B,ASPA,ASPH,SLC4A4,RNF182,N4BP2L1,DOCK11,BACH1,SNAI3-AS1,BBS2,BMPR1B,SYNJ2,MTMR2,C5,NIPA1,OSGIN2,BTRC,CACNA1E,CALB1,DIRAS1,TRIM41,VXN,BRSK2,SPAG9,NEURL1,LOC730101,CCPG1,NUMBL,ADGRG1,CHN2,CASC2,KIAA1549L,QKI,SRP14-AS1,HECTD1,MAP4K4,LY86,FHL5,ARHGEF6,PCYT1B,COL4A5,COL9A2,IFFO1,SMARCAL1,HS3ST5,PREPL,CREB5,HAPLN1,ANKRD44,SNCAIP,TENM4,ATRNL1,NCAN,PHACTR3,PLXNA4,DZIP3,ERC2,UBXN2A,GREB1,KIAA0586,TMEM170A,ARMCX2,C8orf34,TMEM130,PLPPR4,CCDC3,ZNF582-AS1,DLG3,GRIN3A,ACOT8,DSCAM,DTNA,ABCC9,GOLT1B,AASDH,EDN3,EDNRB,ATL1,YAF2,RASA4,TENM1,ELAVL2,ELAVL4,EML1,KCNMB2,RCSD1,SH3YL1,STRADA,TESK2,ZNF589,FER,GTF2IRD2,FGF1,FGFR1,SUCO,UBE2E3,HPCAL4,CAP2,SEMA4D,FLT1,ANKFY1,TRMO,SORBS1,PDLIM5,STAMBP,CAMKK2,KHDRBS3,DACH2,ST6GALNAC3,NRG3,PHYHIPL,DKK3,GABBR1,GABRA2,HRASLS5,CAB39,HBS1L,RAPGEF6,ZNF234,IP6K3,ERAP1,DISC1,CPLX2,GFRA1,GGTA1P,RUNDC3A,RNPS1,LOXL3,GNAO1,GNAS,PRUNE2,GPR22,NUDT21,GRIK1,ADAMTS13,GRIN2C,BVES,RABL2A,ADAMTS6,IRAK3,UBE2QL1,MIER3,SYNPO,HNMT,AGFG1,CELF5,SMAP1,LINC00667,RBPJ,PLD5,TUBB2B,LRRTM3,SLC35G1,KIF5A,KIF5C,A1BG-AS1,STXBP5,TTYH2,LAMP2,LIFR,LIG4,MAP2,MAP4,MBP,MEIS1,KITLG,DBNL,SAMD5,MYCN,MYO7A,NEXMIF,MYT1,NDUFA5,NFE2L2,ALDH1L2,NFYA,CNOT4,LRIT2,NTRK2,SETD4,IGSF11,OCRL,ZNF827,PDCD2,PDE2A,GNG2,GDAP1L1,NALCN,ZNF655,PLXNB3,PRIMPOL,MBOAT7,NXPH1,POLR2F,POU3F2,PPM1B,PPP2R5C,RASGEF1B,PRKCB,PKN2,MAPK3,EPDR1,MAPK10,PRPSAP2,RELN,SLC22A23,UHRF1BP1,MTMR10,ZSCAN32,PTPRB,PTPRE,PTX3,ACSM5,RAB5B,CEP97,ZNF793,SH3TC2,SUSD4,ENOX1,ZNF493,OXR1,RADX,VEPH1,ZDHHC14,MSANTD2,REV3L,MORC4,SLC25A36,RIC8B,NUDT11,RNASEL,RPRD1A,TMLHE,GSTCD,ROBO2,PCMTD2,RPL15,SPIN3,ATP8B4,GLDN,ATAT1,AP1AR,LRRTM4,PRCD,FNIP1,KIF27,SGK1,ITSN1,CPEB3,NLGN1,ST3GAL3,SLC1A3,BTBD3,SMTN,RUFY2,SLC6A1,SLC12A2,SLC15A2,BTBD7,SPHKAP,EPC1,NAXD,OGDHL,ANKRD36,SNRPN,MYO16,USP33,SCN3B,DOP1A,MYT1L,KIF21B,BDP1,NMNAT2,NFASC,CLASP2,TROVE2,POGZ,SS18,NEK4,SEPT8,RGL1,KANK1,GSE1,NSFL1C,NECAB1,VPS13A,NUDT10,ADAMTS17,COBL,ANKRD12,ZEB1,TCF12,USP32P1,HIF3A,SIRT1,SLC44A1,TIAM1,RBFOX2,SEZ6L,TPM1,NPL,WBP2,DOK6,SYNPO2,PRMT8,TRO,STXBP4,TRPC3,PPIL6,TUB,CADM1,RPL7L1,VLDLR,BEST1,XPO1,KCNT2,REEP1,AMZ1,FTSJ1,UPF3A,CA10,SLC30A4,SLC38A1,PRDM10,GAL3ST3,URM1,EPM2A,RGS7BP,FZD3,DOCK8,RTN4,CERS6,RNF170" MicroRNA hsa-miR-888*:mirSVR_highEffct hsa-miR-888*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.49E-131 3.65E-127 8.10E-130 7.46E-129 302 1133 "CPNE2,CLK4,ARID1A,SORCS1,PLEKHH1,FAHD2CP,SLC44A5,MTUS1,OGT,LCORL,DGKD,PPP4R4,ARHGAP5,CDK13,NUMB,RASL11B,CCAR2,ATP1A3,ATP1B3,STX16,ATP2B1,ADAM23,ADGRB3,MPDZ,ZNF599,PROM1,SYNJ1,SCAPER,CA8,KALRN,PTBP2,INA,CDC42,NOG,SRSF11,PPT2,COG1,C4orf33,SULT4A1,NIPBL,TMEM155,FAM149A,AKAP6,SLC25A27,AKAP5,RCHY1,COX4I1,ZFP28,HS3ST5,SLC35F1,CPS1,FAM171B,SH2B1,CRMP1,FEZ2,ARHGEF10,KIAA0040,PHF14,RIMS2,ST18,CYBB,DOCK4,HDAC9,GAPVD1,PABPC5,ZEB2,ZC3H11A,G3BP2,EXOG,CPEB2,RCAN1,DYRK1A,E2F6,EBF1,EDIL3,FAM135B,EDNRA,EDNRB,CNNM1,RBM12,KMT5B,TMEM35A,EML1,CALCRL,EMX2,EPB41,COQ7,RCAN2,RABEPK,DENND4A,EXTL2,EYA1,F3,CLVS1,ZIC4,MED12L,OLFM1,FGF13,SUCO,UBE2E3,SYNCRIP,NELFCD,JKAMP,NSG2,ST6GALNAC3,STAU2,MSANTD4,SARAF,ABLIM2,FYB1,PHYHIPL,STAG2,GABRA1,GABRG2,ARPP21,SALL3,C15orf41,DISC1,KIAA1841,SESN1,PPARGC1A,BRD8,COPS8,GPR75,PCDH11X,ZNF638,CBX1,DCLK2,LNX1,GRIK2,GRM7,GSN,ZBTB49,LINC01551,SOX21,HAS2,ARHGAP36,MIER3,HMGB1,SHISA6,ZNF181,SCIN,IL6ST,ITPKB,JAK2,KCNA2,KCNC2,KCND2,KCNK2,KIF2A,PAXBP1,HECTD2,LSS,MAP2,MBNL1,LDLRAD3,MITF,GIT1,BCO1,MYO6,RTL5,NDUFA5,OTOGL,NFE2L2,SLC11A2,NTRK2,NTRK3,TBC1D25,PCDH8,PCSK1,PDCD2,PDE4B,PKD1,PLCL1,PCDH18,HMGCLL1,LRP12,PSAT1,ING3,SPATA6,MED1,CRLS1,PKIA,RAB39A,PKN2,SLC22A23,SIDT1,MDGA2,CNTLN,SPDL1,PTPRD,PTPRO,ACSM5,RAB3A,SLC6A15,RET,MORC4,SLC25A36,RIC8B,NUDT11,RPRD1A,CCDC82,CARF,ELP2,RPL15,PRR5L,STK32B,LGR4,WLS,RYR3,CCDC112,SBF1,LRRTM4,SCN8A,ELMOD1,SUPT20H,TRA2B,SGK1,FAM102A,DOCK10,FBXO11,FNDC3A,NLGN1,NUBPL,SLC1A7,PREX2,PPP4R3A,BTBD3,WDR47,SLC6A11,SLC12A2,ELMO2,SPHKAP,CPEB4,SMARCC2,RCOR3,SNAP25,USP33,PDZD2,NPAS3,ITPRID2,ZNF302,NKAIN2,NXT2,SYNE2,VPS13A,SYP,SYT4,MTCL1,TAF9,UNC5D,TCEA1,EHBP1,ZEB1,WASHC4,WDR7,ITGB3BP,ZMAT3,HHIP,ARL10,MTMR14,TLL2,C5orf64,TP53BP2,RGMB,TRO,TSN,TTPA,RPL7L1,UBE2H,UBE3A,AMOT,UGT8,SLC13A3,ETNPPL,XRCC4,SF1,ZIC3,ZNF19,KCNT2,ZNF74,EML6,SMARCAD1,PMEPA1,CADM2,HPS4,MDH1B,PCDH15,GAL3ST3,NAV3,KAT6A,SMIM8,PHTF2,JMJD1C,TIGD6,RNF170,KLHDC1,FRMD6,NETO1,DPF3,SLC4A10,GAN" MicroRNA hsa-miR-297:mirSVR_lowEffct hsa-miR-297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.53E-131 3.67E-127 8.14E-130 7.49E-129 360 1605 "ABAT,ARID1A,XKR4,TMEM132B,GALNT13,SLC12A5,PNMA8B,GRAMD1B,RNF150,ESYT2,BEND6,SLC44A5,SORCS2,TAOK1,FAM135A,ZFAT,PHF12,PKP4,VAT1L,APP,LGR5,ARHGAP5,CDK13,ASPH,ZBTB10,TMEM108,ATM,B3GALT2,RIPK1,NRP2,CDK5R1,DST,JAZF1,CACNB4,PTBP2,CH25H,ISPD,RUNX1T1,ZNF501,CCNH,MTMR7,CDC42,SRSF11,CHN2,DGCR9,TJP2,QKI,IGLON5,ARHGEF6,COL4A5,BTF3L4,AKAP5,AHCTF1,ZFP28,MFSD4A,CREM,CRHBP,AKAP12,GDA,SOCS5,SLITRK5,APPL1,PLCXD3,CFAP61,PUM1,RIMS2,ST18,KIAA0408,DOCK4,GPRASP1,DCAF8,ZNF337,LIN54,KIAA0586,INTS1,DGKG,GIT2,YTHDC1,ZEB2,MFAP3L,HP1BP3,MAGI2,RHOBTB1,SRGAP3,NTM,DLG2,DMD,SLC12A6,DTNA,DYRK1A,ABCC5,AASDH,WDPCP,EDNRB,HIPK3,SYT15,TMTC1,RBM12,EIF4G2,EIF5,TENM1,ELAVL4,VPS13B,EPB41L2,RABEPK,STX2,EPS8,NCALD,CEP85L,ZNF549,KATNAL1,EYA1,MRVI1,WAC,CEP78,TOMM40L,ZNF589,FGF12,FGFR3,FHL1,POLK,SCARA3,EVL,SORBS1,UFM1,NPTN,DACH2,ST6GALNAC3,CSPG5,KBTBD12,TVP23A,GAB1,GABRA5,CHL1,GAD1,ARPP21,ZNF559,LRRC37A6P,PCDH17,LYVE1,GLI2,GLRB,GLS,GPR34,NUDT21,PCLO,RAPGEF4,ATP2B1-AS1,GRIA1,GRIA2,DIDO1,GRID1,GRM1,ZNF496,TMEM25,LINC01551,MAP4K5,MAEL,FRMD3,GABARAPL2,HNMT,TCEAL6,SHISA6,HTR5A,IGFBP1,RBPJ,LRRCC1,USP54,LRRTM3,ITGAM,ITGAV,SLC35G1,KCNA4,KCNK1,CYP27C1,LAMP2,LIFR,HECTD2,LYPLAL1,SYT9,CHIC1,TM6SF1,SHC3,MEF2C,KITLG,POC1B,AFDN,XRRA1,MOBP,CD200,MPP2,COMMD5,ADAM22,PABPC1L2A,NCAM1,NEK1,NFIA,NHLH1,CNOT4,DNHD1,NPTX2,HCN1,NTRK2,OPCML,FAM225B,OPHN1,OXTR,P2RX7,TREM2,PAK3,CNTN3,DPY19L2P2,PCSK5,PDE3A,PDE4A,PDGFRA,ENPP2,FAM98B,CDK14,DUSP26,SSH1,PLIN1,MTRF1L,PMP2,EPB41L4B,FAT3,NXPH1,MED1,MINDY2,PPM1B,PPP2R2B,LRRN3,PPP3CA,PRKAB2,HYDIN,PROX1,KLK6,SNRK,PTN,PTPRB,FAM120C,CEP97,FAT4,RAP1GAP,OXR1,UBR7,RGS4,TTLL7,RPRD1A,ZFHX4,GSTCD,RPL15,SPIN3,ACER3,PTGR2,KCNIP3,RYR3,CCDC112,ASIC4,TRIM46,MRAS,SH3BGR,ITSN1,PPM1E,ARX,PAAF1,PPP4R3A,SMTN,TRIM67,SLC12A2,SLC22A4,SLIT1,MAST1,SORCS3,ANKRD36,MBD5,CABCOCO1,ZNF415,DOP1A,SON,ENKUR,ERC1,KIF1B,CDK19,RBM26,C11orf87,PBLD,SAMSN1,SSTR1,LARP4,ZSCAN29,DIP2A,AJAP1,ACSBG1,NECAB1,PLCB1,COBL,ANKRD28,TACR1,KAZN,DDHD2,CAMTA1,EXOC7,FAM208A,UNC5D,WWC1,TBCEL,TBX15,ZFP90,CUX2,TCF7,ZEB1,WDR7,DOCK9,RALYL,SLC35G2,CYB561A3,ITGB3BP,GZF1,ZFP91,NR2E1,HEY2,KAT6B,TPM3,C9orf85,AMACR,ANKRD20A2,TMEFF2,FAM155A,AMOT,ZNF781,GUSBP1,CFAP298,ZIC2,ZNF711,ZNF19,ZNF24,TRIM9,PLPP4,CELF4,REEP1,SPIRE1,UPF3A,DNALI1,EVI5,PRDM8,TMEM163,LINC00632,GOPC,DNAH10,FZD3,DOCK8,KAT6A,CERS6,ADAMTSL3,JMJD1C,TIGD6,FXR1,IFT88,SOCS4" MicroRNA hsa-miR-1260:mirSVR_lowEffct hsa-miR-1260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.97E-131 5.04E-127 1.11E-129 1.03E-128 382 1800 "SDE2,ASPHD1,ASIC2,ABHD6,TMEM132B,GALNT16,GALNT13,SLC12A5,PNMA8B,GRAMD1B,LRFN2,TAOK1,UNC79,SYT13,PDZD4,OGT,SEMA7A,CCDC146,PPFIA4,SUGT1P4-STRA6LP-CCDC180,KCNAB2,APBB2,GPAM,PHYHD1,VAT1L,APP,AQP6,SEMA4G,SPTBN4,ARRB2,MARK4,TMEM108,ATP2B1,ATP2B2,ZNF583,BBS2,DCAF5,CFLAR,BTK,MTMR3,C1QC,CACNA1I,CACNA1G,CDK5R2,CA4,CACNB2,CACNB4,KALRN,NGB,PRC1,ARHGEF25,CBLN1,KRIT1,P2RX6,CDC25B,DCLK1,LRRFIP1,LGI1,L3MBTL4,UBE2L6,CHRM1,PLEKHB1,TAOK2,ARHGAP22,LHX2,IGFBP7-AS1,ZFYVE9,MAP4K4,ARHGEF6,COL4A5,SUMF2,IFFO1,MFSD4A,ZNF385A,ANKRD44,NCOR2,ABCG1,RGS6,LRIG1,ARHGEF10,MICAL2,OSBPL3,PLCH2,VAC14-AS1,CST3,PLXNA4,SLITRK5,GREB1,RIMS2,RUBCN,CYBB,RIPOR2,ARHGAP24,DCAF8,RASSF2,LIN54,PHYHIP,TOMM20,SPOCK2,AIF1L,GIT2,ARMCX4,ZEB2,ELMO1,CNIH3,C2CD2L,GUCD1,SRGAP3,RABGAP1L,TMCC2,ARNT2,ZNF582-AS1,DLG2,HS3ST4,USP3,NR1D2,CDON,DOCK2,DTNA,DTNB,DYRK1A,ABCC9,EDNRA,YAF2,EFNB3,CELSR3,GPR61,KMT5B,EMX2,COQ7,LRRC17,RASGRP2,MTSS1L,EPHB1,SPEG,ETV1,TLR7,SIRPB1,EZH1,NRN1,CACNG2,CORO2B,FCGR1A,FCGR3A,PPP1R1B,SLC9B2,POLR1B,FGF14,FHL1,CAP2,FOXM1,FLT1,CAMKK2,ATP2C1,ERGIC3,KBTBD12,ABLIM2,TVP23A,STAG2,MEGF11,GABBR1,GABRA3,GAD1,ZMYND11,JPH4,RAPGEF6,SIGLEC8,ALDH1L1,GGT7,ZNF276,GLUL,DCLK2,LILRB4,TMEM121B,RAPGEF4,GRIA1,GRIA2,GRIA4,PLPP7,ADAMTS13,RNF165,PTPN5,BVES,PSIP1,TMEM179,NCKAP1L,ARHGAP36,VSIG4,ELOVL5,AGBL5,HNF4G,HNRNPK,USP51,HSF2,CELF5,IRF8,MSL1,MYLK2,SCRT2,IL11RA,LRRTM3,ITGAM,KCND1,KCNJ11,KCNMA1,KIF5A,STXBP5,LAMP2,LIMS1,MAT2A,IL17D,CHIC1,MDM4,MEF2C,MEIS1,MIA2,MMP16,MOBP,ZNF92,MYO7A,NDP,CCDC13,NEK1,NINJ2,NOS1,SLC11A2,NTRK2,NUMA1,TBC1D25,SNTG1,PDE1A,PDE2A,ABCB1,GDAP1L1,SSH1,CAMKV,ZFYVE21,GPSM2,STRN3,RC3H2,PSAT1,SCHIP1,ING3,SEPT4,PACSIN1,FSD1,PPARA,PPP1R1A,PTPA,MAPK8,MASP1,SLC22A23,CYBC1,MDGA2,TMEM104,CNTLN,UHRF1BP1,MTMR10,PTPRG,FAM120C,PEX5,ZNF615,PID1,CCDC40,PLEKHB2,FAM66C,SH3TC2,ATG16L1,RAP1GAP,FIGN,RFX3,RFX4,RGS3,RGS4,SUGCT,EXD2,GSTCD,CYB561D1,TMEM100,EPHA10,RPL15,SPIN3,GLDN,LGR4,SOX8,RTN1,TMEM156,ATXN2,LINC00461,PRCD,ASIC4,ZFP2,SOX6,TRIM46,STUM,ASRGL1,SGK1,CHD9,ST3GAL3,ANKRD6,SLC1A6,BTBD3,RUFY2,SLC6A9,SLC14A1,ANKRD36,INAVA,LIMCH1,DOP1A,NMNAT2,CLUAP1,EMC1,KDM4C,PEG10,ATP10B,POGZ,SMOC1,ZC4H2,LRRC4,CEP68,VAMP1,NUDT10,SYPL1,TACC1,EXOC7,TAL1,KIAA0930,CLASP1,TMEM151B,SLC19A3,TNS2,CYB561A3,AP4E1,ZNF106,BHLHB9,DAAM2,C5orf64,TP53BP1,ZNF346,METTL3,PRMT8,TRH,NUTM2A,DCBLD1,RUSC1,SSBP2,TUB,ZKSCAN5,UBTF,GORASP1,BCL2L13,WIPF1,LAT2,LGI4,ZBTB14,ZNF708,TRIM9,ZNF74,SLC26A10,SPIRE1,WNK1,EMSY,PRDM2,STMN4,VPS35L,PPP1R3F,ITM2C,WIPF2,SLC17A6,PAK5,TMEM63C,FBXO36,CASC15,NUP214,FAM219B,JMJD1C,ZNF248,TIGD6,FXR1,IFT88,PRRT4,FAM198A" MicroRNA hsa-miR-939:mirSVR_lowEffct hsa-miR-939:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.48E-130 8.32E-127 1.84E-129 1.69E-128 355 1566 "DPF1,TTYH1,SDE2,ASPHD1,CLK4,KDM5D,CSMD2,NDRG2,GALNT13,ADCYAP1R1,SLC12A5,GRAMD1B,KIDINS220,AP2A2,TBC1D14,KIAA1324,C1QTNF1,SPOP,USP35,CARNS1,GOLGA7B,PPFIA4,CNIH2,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,DGKZ,APOC2,BCAS1,API5,MIER1,CDK10,PRX,ARHGDIA,ARNTL,LINC00173,CDK13,CCDC74A,ASPH,ZSCAN18,DACT3,PCDHGB4,BRINP2,ASTN1,TMEM108,ATM,EIF4G3,ALDH7A1,CADM3,KIF1A,GPR146,CFLAR,KSR1,LINC00906,CFAP410,CACNA1E,CACNG1,CALB2,KALRN,NGB,CAMK2A,CBFA2T2,ENTPD6,DGKI,AP4M1,DCLK1,EVI5L,LOC730101,TAOK2,NRXN3,NRXN2,CLU,ABCG2,TMEM184B,SRP14-AS1,TMEM155,AKAP6,BTF3L4,COL11A2,GAL3ST1,IGDCC3,ZNF385A,NCOR2,CLIP3,TRIM69,AATK,MICAL2,CSNK1E,OSBPL3,ATRNL1,VCAN,RIMS4,VAC14-AS1,PLXNA4,GREB1,ARHGEF4,NRSN1,EDRF1,CX3CR1,CCDC144A,ZNF337,SCRN1,ZNF804A,COPS7A,CEP170,MAGI2,KLHL3,SPOCK3,SGSM2,G3BP2,CCDC3,ARNT2,DLX1,DNM1,DNM2,FAM57B,RCAN1,ABCC5,EBF1,FAM135B,PHC2,CACNG7,OPTN,CELSR3,SUGP2,RASA4,IRAK4,CERCAM,ELN,EPB41,EPB41L1,EPB41L2,EPHB1,ANKRD13B,ERBB4,SPEG,CDHR1,TUBB4A,RACK1,FCGR1A,FCGR1B,ZSCAN30,KAT8,SPSB4,TMEM164,AMOTL2,MEGF10,GABBR1,GABRA3,GHDC,CPLX2,ALDH1L1,GFAP,GGT7,C1QL1,KIRREL3,GLUL,AIFM3,POLL,DCLK2,GNG3,GOLGB1,PRLHR,GPR12,PCLO,GRIK3,ADAMTS13,GRM1,PTPN5,GSTM5,FAM107A,ATOH8,FAM222A,CELF3,ZHX1,LRRC75A,HTR5A,SCIN,INPP5B,INSM1,ZNF385B,METTL21A,KCNA4,KCNN1,CREG2,LINC00634,ZFYVE27,MAP4,MAP6,MGAT3,MID1,XRRA1,MN1,MOBP,MSI1,MYO7A,PABPC1L2A,FXYD7,FXYD6,CCDC13,NOVA1,SMIM11A,NUCB2,TBC1D25,GPR137C,ZNF827,PCDHGC3,PCMT1,CDK18,PDE1B,PDPK1,PFKFB3,GDAP1L1,CAMKV,KCTD15,FAM216A,FTO,FXYD1,PLXNB1,SDK2,POLR2F,MED1,PPP2R5E,KANSL1,NKAIN4,CEP41,NDUFS7,WDR25,PTHLH,PTPRE,PTPRH,RAB5B,USP47,FAM66C,IQSEC3,NWD1,BSDC1,DUSP15,DPF2,RFX4,RFX5,RNF220,C12orf49,KLHDC8A,ARMC5,ELP2,SNX22,GLDN,PRR5L,STK32B,EMID1,RXRG,ZNF331,LRRTM4,SOX6,SELL,COPZ1,FAM102A,FERMT1,NTNG1,PAAF1,PPP4R3A,SLC6A1,KANSL3,PKNOX2,SLC8A2,RAB3GAP1,SLC11A1,LGI3,ARFGAP1,GKAP1,OGDHL,SMARCE1,INAVA,MAPKBP1,SNCA,FAIM2,DOP1A,SON,PDZD2,WDTC1,KIF21B,ZSWIM8,CAND2,SPTB,DDN,C11orf87,CAMTA2,SSTR2,ZC4H2,SSPO,STAU1,SYT11,FGD4,RHBDL3,SYN1,COBL,SLC37A2,POPDC3,TAL1,SMG6,SIN3B,CUX2,TCF7,TCF7L2,ZEB1,USP22,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PHF24,TMEM151B,FAM189A1,PCDHB4,ARHGAP9,AHCYL2,SIK3,RNF216P1,ATP13A2,GALNT17,TIE1,ICAM5,ERCC6L2,CSMD1,ZNF384,RGMB,ZNF346,TRH,KCNE5,HEPACAM,CLEC2L,UBTF,OSBP2,CLIP2,PORCN,SF1,LAMP5,INTS3,PRDM2,LRP8,URM1,SNX27,CAB39L,UBE3B,PHTF2,TTC7A" MicroRNA hsa-miR-188-5p:mirSVR_lowEffct hsa-miR-188-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.58E-130 1.45E-126 3.20E-129 2.94E-128 340 1442 "TTYH1,SDE2,KCNH8,ACADM,NDRG3,ADCY6,TMCC3,ADD2,PWWP2A,ADORA3,MTA3,AP2A2,TBC1D14,AK2,ZNF578,SEMA6A,ABCD2,AMPD2,AMPD3,OGT,LCORL,SUGT1P4-STRA6LP-CCDC180,ANXA7,UPRT,GPAM,SHTN1,LGR5,SPTBN4,PLA2G4C,DDX3Y,ATM,SLC4A4,ATP1B3,ATP2B1,DPY19L3,ADAM23,BCL2L2,BMPR1B,SYNJ1,SYNJ2,JAZF1,CACNA1G,OSGIN2,CACNA1A,CACNB2,CACNB4,CALB2,CABP7,SPAG9,CD86,CD38,REPS2,CDC25B,CDC42,LGI1,LOC730101,CFL2,CHM,CHN2,MYL6B,IGLON5,PCYT1B,ARMC8,AKAP6,SLC25A27,SLC4A8,ACBD5,ZNF521,ZFP28,FAM171B,RBM39,MROH8,SEC24C,MICAL2,CSNK1G3,SIPA1L1,VCAN,PDE4DIP,PLXNA4,DZIP3,CTH,RIMS2,CX3CR1,CCDC144A,TCAF1,LONRF1,DNAL1,ELMSAN1,ZEB2,MFAP3L,KIAA0319,GUCD1,SV2B,DMTF1,PDCD6IP,ECM2,MAMLD1,DNM1L,ANKRD46,EFNB3,SUGP2,APH1A,IRAK4,PLEKHA1,ING4,TMEM35A,EIF1,EPB41,EPB41L2,ZNF549,RCSD1,ADGRV1,WAC,TMEM132C,ACSL4,CEP78,CHST15,ZSCAN30,PRMT5,FGFR1,CAMSAP1,POLK,SYNCRIP,AGAP3,RGPD5,ATP13A4,ANKFY1,SGIP1,SLC37A3,AKAP3,SORBS1,SMC2,USP16,RASL10A,ARFGAP2,KHDRBS3,NSG2,ST6GALNAC3,NSG1,TBR1,NRG3,STAG2,GABRA2,TRAF3IP2,ILDR2,HBS1L,SEPT9,GPR162,CYP46A1,ADAM28,GGT7,GLYR1,TOX3,GLUL,PCDH11X,RAB40B,GPD2,GPM6B,GPR19,STON1,LPAR4,TPPP,DIDO1,GRIA4,GRM7,FAM19A2,COQ10A,FAM107A,ZHX1,FRMD3,ARHGAP36,ELOVL5,HMGB1,GABARAPL2,AGBL5,HMX1,HNF4G,DHX35,LRRC75A,SMAP1,IRF8,IL12A,LRRTM3,ITGA7,JAK2,METTL21A,KCNA1,GPR62,KIF5A,STXBP5,STMN1,MEF2C,MEIS1,MEIS2,MEST,MITF,AFF1,CD200,SAMD5,MSR1,N6AMT1,SCG3,MX1,MXI1,P2RY13,NCAM1,ZC3H12B,NOVA1,NRCAM,HCN1,NTRK2,P2RX7,PBX1,PCMT1,CDK18,PDE4A,PDGFRA,BEST3,PFKFB2,PIK3R1,FAM218A,A2ML1,CCSER2,LRP12,SLC36A4,POLR2F,TATDN3,PPP3CA,PPP3CB,EPDR1,MAPK9,MASP1,SYTL2,PTCH1,NCR3LG1,PTPN13,PTPRB,FAM120C,FAM66C,ZNF793,RASGRF1,ZDHHC14,BSDC1,ZYG11B,UBR7,KIF7,LGI2,GSTCD,CYB561D1,NEK11,ATP8B4,STK32B,TMEM156,ATXN1,TRIM46,CASC3,ASRGL1,ARX,FBXO11,FNDC3A,PEX26,KANSL3,PKNOX2,YPEL4,SLC12A2,ELMO2,ATF7IP,TET1,ARFGAP1,MYH15,MBD5,SNRPN,UNC80,SON,BDP1,ZNF423,KIF1B,CDK19,NFASC,LMO3,SRPK2,POGZ,ITPRID2,ZC4H2,NKAIN2,LRRC4,SS18,ERBIN,CEP68,GSE1,SYNE2,VAMP1,ARHGEF9,SYPL1,MTCL1,PJA1,FAM208A,MGRN1,SATB2,TCF12,CLASP1,SYNE1,DOCK9,RALYL,SLC19A3,PCDHB3,FAM200B,DICER1,SIRT1,TLL2,RBFOX2,TPM3,AMACR,ZMYND8,FAM155A,UBE2H,SLC35A4,UBE3A,VAV2,TBC1D15,VSNL1,NSD2,SF1,PCDH20,MICU3,TRIM9,ATP6V0E2,ZNF74,CELF4,ZBTB16,TMEM237,POLR3H,EVI5,PRDM10,HPS4,CERS6,FAM219B,JMJD1C,SOCS4,LAS1L" MicroRNA hsa-miR-4326:mirSVR_lowEffct hsa-miR-4326:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-130 1.81E-126 3.97E-129 3.66E-128 370 1700 "RALGAPA1,SYS1,ACTN1,NDRG3,KLRC4,ADCY6,TMCC3,ADRA1D,BEND6,SLC44A5,ZNF608,SNX32,ADGRF5,ALAD,UNC79,FAM135A,AMPH,CCDC146,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBA2,APOC1,VAT1L,USP37,ZFYVE28,NCOA1,CCAR2,TMEM108,ATP1A1,EIF4G3,N4BP2L1,LINC00847,BMPR1B,SYNJ1,SYNJ2,SCAPER,CASTOR3,MTMR3,MTMR2,GYG2,CACNA1A,KALRN,ISPD,SPAG9,NFS1,USP6,RGN,CDC42,DCLK1,LOC730101,CCPG1,IGFN1,CACNA2D2,LHX2,KMT2C,RAB28,NRXN3,CLCN3,KIAA1549L,FBXO7,ABCG2,TMEM184B,TMEM155,CNR1,AKAP7,AKAP6,TBPL1,ZNF521,NRG2,CP,GDA,MICAL2,VCAN,KIAA0040,CFAP61,RUBCN,CX3CR1,NOS1AP,DOCK4,RIPOR2,SNPH,LONRF1,TBC1D5,PHYHIP,DGKG,BRINP1,DNAJC6,RUSC2,DDX46,SMG7,SRGAP3,WDR20,DLG2,DLX1,NYAP1,MED12,DPYSL2,PDCD6IP,DYRK1A,DNM1L,CNNM1,RASGRP1,TMTC1,CELSR3,PHF20L1,MRO,ABI2,EGR3,TENM1,EPB41L1,RABEPK,NCALD,EFS,REEP2,CLVS1,NSRP1,ATP8A1,CEP78,TOMM40L,FCGRT,PRMT5,ZNF589,SEC24B,OLFM1,AMOTL2,VTI1B,SLC37A3,HVCN1,NRG3,GABRG1,TRAF3IP2,RAPGEF6,ERAP1,ZNF559,DISC1,SEPT9,ACSS1,GCNT2,PPARGC1A,GLI2,ZNF638,DCLK2,ZNF782,GPT2,PRLHR,C1QL4,ADAMTS13,GRIN2C,GRM7,GRM8,CIT,RNF165,KAT7,MFSD2A,LINC01551,SOX21,MAP4K5,CELF3,UBE2QL1,ARHGAP36,HMGB1,HMGCL,AGBL5,SHISA6,FAM95B1,IGF1,DOCK7,LRRCC1,SCIN,IL6ST,IL12A,KCND1,KCNH1,KCNH2,KCNJ10,KCNJ16,KPNA5,TTYH2,SFXN5,LIMS1,PAXBP1,HECTD2,CLEC18A,MARK3,MATN2,MBNL1,LRP1B,MEIS2,KCTD6,MID1,MMP16,MOBP,SESN3,MSR1,MTR,RSPO2,MYO5A,P2RY13,NEFH,NEK1,SLCO1C1,NME4,NUCB2,OGDH,OPHN1,GLIPR1L2,PAK3,PCDH8,PCMT1,CDK18,ENPP2,PDYN,GNG2,PFKFB3,OLA1,PIK3C2A,SNX10,RETREG1,PLCB2,JAKMIP1,C11orf49,SEPT4,TNPO2,NXPH1,POU3F2,POU6F1,PPP1R1A,PPP2R5C,RASGEF1B,PRKACB,PKIA,PRKCB,RAB39A,PRKCZ,HYDIN,MASP1,DEF8,WDR25,PIGG,PXK,PTN,OCIAD1,FAM120C,ACSM5,TMEM231,ROGDI,RBBP6,KHDRBS2,SLC6A15,RGS12,ARHGEF10L,SLC25A36,RIC8B,PBRM1,SETD5,ALG9,TMEM206,TMEM100,ARMH4,LRRK2,SYNDIG1,NCBP3,RMI1,DGLUCY,SCP2,PEAR1,FAM102A,SH3GL3,KIF16B,FNDC3A,NLGN1,SLA,ZNF365,SMTN,FAM214B,SLC9A5,ELMO2,EFHD1,SLCO1A2,ZFP1,GKAP1,SORCS3,CDK5RAP2,MYH15,LIMCH1,RIMS1,MBD5,ZNF415,UNC80,WDTC1,TRERF1,BDP1,FNBP1,MYCBP2,KDM4C,SAMSN1,TTBK2,SULF2,FGD4,SYNE2,PLCB1,SYPL1,PDLIM2,FBXW11,TBX15,EHBP1,VWC2,TCF4,CUX2,TCF7,ZEB1,SYNE1,NAT16,PCDHB3,ARHGEF12,PUM2,FAM200B,DICER1-AS1,ITGB3BP,ARL10,TJP1,NR2E1,ERCC6L2,TMPO,FAM124A,R3HDM1,RBFOX2,TPM1,NPL,TPM2,ZNF384,ZNF346,RUNDC3B,AMACR,STXBP4,TMPRSS5,TSC1,RFTN2,HEPACAM,CADM1,UBE3A,AMOT,OSBP2,TBC1D15,XRCC4,ZIC2,ZNF24,ZFP41,SLC26A10,CELF4,TMEM198,UPF3A,PRDM2,EVI5,ADAMTS9,CIAPIN1,PCDH15,URM1,TRIM16L,WIPF2,FAM13C,RTN4,PAK5,KAT6A,RNF170,RNF146,SOCS4,LAS1L" MicroRNA hsa-miR-3201:mirSVR_lowEffct hsa-miR-3201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-130 1.91E-126 4.19E-129 3.86E-128 311 1209 "RALGAPA1,KCNH8,CLK4,NCKAP5,NDRG3,GALNT13,INTS2,CC2D2A,ZNF578,SMIM17,SPOP,ALCAM,SRPX,GOLGA7B,EP400,PPFIA1,ALS2,CACHD1,ASTN1,ATP2B1,ZNF582,ADAM15,ADGRB3,BCL2L2,CFLAR,DST,C5,OSGIN2,CA8,CACNA1E,KALRN,PTBP2,RUNX1T1,CLDN10,KRIT1,CCNH,P2RX6,CDC25B,CDH10,DCLK1,CLGN,NOG,CFL2,COPB2,SRSF11,CASC2,B4GALT6,TJP2,ABCG2,MAP4K4,CNN3,AKAP7,IQCK,AKAP6,ABI3BP,MFSD4A,ENTPD4,SLC32A1,ANKRD44,SNCAIP,ATRNL1,PDE4DIP,DZIP3,EDRF1,CYBB,BOC,RIPOR2,FRMPD4,HDAC4,PHF19,LONRF1,DGKG,ELMSAN1,ZEB2,TIAM2,HP1BP3,FBXL5,KIAA0319,RHOBTB1,PLPPR4,SRGAP3,TMCC2,DLG2,DMD,DMTF1,DPP6,ABCC5,DNM1L,EBF1,WDPCP,EDN3,ANKRD46,HEYL,SEMA3D,YAF2,MBNL2,AASS,KCTD3,EIF4G2,CALCRL,PAN3,EIF1,EPB41,EPB41L1,STX2,ZNF549,ETV1,DNAJC27,GMPR2,TUBA1B,TAOK3,SPSB4,FGF12,MEX3B,CAP2,FOXO3,NBEA,TRIM16,GPR153,DLL3,MPP6,GABRA2,GABRB3,GABRG1,BRPF3,ARPP21,ZNF234,DISC1,LRRC37A6P,GATM,NEU3,AHDC1,MMADHC,GLS,TOX3,TNRC6A,GPD2,GPM6A,STON1,PCLO,GRIA2,GRIK1,GRIK2,GRM1,GRM7,FAM19A2,RNF165,FAM107A,GUCY1B1,RASSF8,PADI2,HLF,ZNF491,ZDHHC15,SMAP1,DIPK1A,RIPPLY2,KCNJ10,KLRC2,CAMK2N2,STMN1,LIG4,PAXBP1,HECTD2,PACRG,MATN3,MBP,SYT9,CHIC1,LRP1B,SHC3,MEF2C,MEIS2,MOG,CTNNA3,MYO9A,ZNF862,NDP,NEK1,NEUROD1,NHLH1,CNOT4,DNHD1,SLC11A2,PBX1,PCSK5,PDE2A,PDPK1,GDAP1L1,STRN3,LRP12,NXPH1,POU3F2,MED1,PPP2R2C,PKIA,HYDIN,MDGA2,UHRF1BP1,PTPRD,ACSM5,CEP97,PLEKHB2,SH3TC2,RASGRF1,DBX2,ZDHHC14,REV3L,RFX4,RNH1,CCDC82,C12orf49,UEVLD,ADAL,ACER3,RPS6KA2,LRRK2,WLS,AP1AR,SALL1,SCP2,SEC14L1,MRAS,CPEB3,MAGI3,FBXO11,FHOD3,NLGN1,PAAF1,SLC1A3,FAM81A,SLC6A1,KANSL3,YPEL4,CCDC88A,EFHD1,BTBD7,SPHKAP,CXXC4,SORCS3,RCOR3,KIF13A,SNRPN,MYT1L,BDP1,HECW1,MYCBP2,KDM4C,IQSEC2,NFASC,TAB2,ITPRID2,STOX1,AJAP1,RHBDL3,VPS13A,PJA1,EXOC7,CNTN2,KIAA1107,TBL1X,ANO4,DMXL2,CUX2,TRIM2,RPGRIP1L,WASHC4,CLASP1,NSD1,TEK,CRB1,AP4E1,SLC44A1,TIAM1,TLR4,ERCC6L2,FAM124A,CSMD1,CABIN1,PIK3R5,NPL,TPM4,SYNPO2,TRIO,PDSS1,TTC3,PRR18,FRRS1L,VLDLR,WIPF1,XPO1,XRCC4,PLPP4,LYPD6,ZBTB38,EML6,ANKS1B,SMARCAD1,CADM2,SLC38A1,CSDE1,ADAMTS9,PCDH15,NAV3,NAV2,FIP1L1,TRIM16L,TIGD6,RNF170,FRMD6,NETO1" MicroRNA hsa-miR-943:mirSVR_lowEffct hsa-miR-943:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.41E-130 1.92E-126 4.19E-129 3.86E-128 331 1369 "TTYH1,KCNH8,CLK4,RNF150,BEND6,ZNF608,AK2,ARHGAP20,PCDH10,GPRASP2,AMPH,ANK2,MYH7B,PPFIA1,FAM131A,CACHD1,BCAS1,USP37,SHROOM2,AQP4,ARNTL,MARK4,SLC4A4,RNF182,ADAM15,BBS2,BCHE,BID,BMPR1B,C5,NIPA1,OSGIN2,WASF1,CACNB2,CALM1,KALRN,CAMK2G,CAST,METTL6,SLC16A4,ARHGEF1,CBFA2T2,CDH8,LRRFIP1,EVI5L,IGFN1,NOG,SYNPR,NDST3,ARHGAP22,KIAA1549L,TJP2,QKI,MAP4K4,NIPBL,ARMC8,NECTIN3,ANKRD44,CSF1R,RGS6,ARHGEF10,OSBPL3,CSNK1G3,SLITRK5,KIAA0040,ARHGEF4,CTNND2,RIMS2,ST18,KIAA0408,DOCK4,ARHGAP32,SNPH,ARHGAP24,DCAF8,DGKB,ZEB2,KIAA0319,PARD6A,G3BP2,CHRDL1,EXOG,DMD,SLC29A4,CPEB2,ABI1,PDCD6IP,GNE,DTNB,DUSP9,ABCC5,DNM1L,KRBA2,E2F6,AASDH,EDN1,SGK2,HIPK3,RASGRP1,SEMA3D,MBNL2,KMT5B,AASS,EPB41L1,LRRC17,ETV1,F5,SCML2,ATP8A1,ZNF589,FER,SUCO,ATP13A4,ANKFY1,NBEA,SMC2,HVCN1,ATP6V1H,KBTBD12,B3GAT1,AP4B1,CHL1,GABRB1,GCNT2,TUBGCP4,PPARGC1A,LYVE1,RAB30,TOX3,LUZP2,GNAL,ZNF782,ADGRA3,GPD1,GPD2,TDRKH,EML4,FAM19A2,BVES,FAM107A,ATG4C,IRAK3,NXPH2,HLF,GABARAPL2,HMGCL,AGBL5,HNMT,ZDHHC15,HTR5A,IRF8,MSL1,LINC00667,C2orf72,ZIC5,IL6ST,INPP5B,ITGAV,SLC35G1,KCNA4,KCND1,KCNMA1,STXBP5,ARHGAP12,PIK3AP1,ZNF667-AS1,MBNL1,MBP,MEIS1,POC1B,MMP16,BLOC1S2,MSRA,MYCN,NCAM1,NPTX1,NTRK2,OPA1,P2RY1,PBX1,PDE4B,PFKFB4,PIK3C2A,PLTP,C11orf49,NXPH1,PPARA,MINDY2,PPP1R1A,CCDC144B,PRKACB,PRKCB,PRKCG,PKN2,HYDIN,CNTLN,ANKHD1,UHRF1BP1,PTPRB,TUG1,TMEM231,FAM66C,SH3TC2,MSANTD2,SLC6A15,REV3L,RGS3,RNASEL,ALG9,ROBO2,ELP2,PCMTD2,MRAP2,ZC3H14,MCMBP,GLDN,SYNDIG1,ST6GALNAC6,WLS,RYR3,ZNF331,AMER2,ATXN2,SCN2A,PRCD,GALNT10,TRA2B,KIF21A,PPM1E,DOCK10,MAGI3,AMBRA1,FBXO11,CCDC92,DZIP1,ANKRD6,CLSTN1,SLA,ZNF365,KANSL3,SLC14A1,SLCO1A2,SMARCA4,MAST1,SMARCD3,ANKRD36,RIMS1,MBD5,FAM219A,BDP1,FNBP1,ZSWIM8,SP4,CAND2,UHRF1BP1L,KDM4C,SPART,CLASP2,CLSTN2,COLGALT2,STOX1,NKAIN2,SS18,KANK1,SULF2,ACSBG1,FGD4,C3orf70,SYN2,TAC1,PJA1,UNC5D,ADGRL3,VWA3A,DMXL2,TPCN2,DOCK9,PCDHB7,TNS2,GPRIN3,PMS2CL,ZFPM2,AP4E1,ARL10,TIAM1,MTMR14,TMEM9,DDHD1,TLR4,DAAM2,KAT6B,TPM4,ZNF384,TRIO,RUNDC3B,AMACR,TRPM2,PPIL6,TMPRSS5,TSN,SSBP2,TTTY15,PLEKHH2,BCL2L13,VLDLR,WIPF1,CLDND1,RICTOR,ZIC3,ZNF24,ZNF28,TRIM9,ZNF45,SPHK2,POLR3H,AMZ1,ZFAND5,SYNC,CADM2,NAV3,MVB12B,PLSCR4,ST7,UBE3B,FBXO36,JMJD1C,TRAM2-AS1,ZNF248,RNF170,FRMD6,AP3B2" MicroRNA hsa-miR-632:mirSVR_lowEffct hsa-miR-632:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.63E-130 2.60E-126 5.68E-129 5.23E-128 365 1658 "ABR,SYN3,ACTN1,CSMD2,PLEKHG5,DSCAML1,KIAA1211,MTA3,PCDH19,DISP3,CC2D2A,ALAD,CEP126,ABCD2,CARNS1,GOLGA7B,PPFIA1,SUGT1P4-STRA6LP-CCDC180,FAM131A,APP,LGR5,AQP4,CDC14B,ARNTL,ARRB1,NUMB,ATP1A2,EIF4G3,SLC2A11,CADM3,RIPK1,BACH1,FGF17,SYNJ2,ARHGEF7,FUBP1,LINC00906,CACNA1I,MMD2,CACNA1A,CACNA2D1,CALB2,CABP7,BRSK2,ISPD,MAP7,RUNX1T1,INA,P2RX6,SCARB1,MYOM2,CDH8,CDH10,LRRFIP1,CLGN,CACNA2D2,CHN2,PLEKHB1,CASC2,EPS15L1,KIAA1549L,NRXN2,TPP1,DGCR9,QKI,MAP4K4,NIPBL,FAM149A,WHRN,SUMF2,LETMD1,SMARCAL1,TOGARAM2,MFSD4A,CHD1L,CPS1,PNKD,PREPL,C2CD2,GDA,ARHGEF10,NCAN,DZIP3,UBXN2A,PHF14,GPSM1,DOCK4,ARHGAP32,KATNAL2,SNPH,ARHGAP24,TOX,PHF19,EARS2,ZNF337,LIN54,DGKB,DAPK1,GIT2,YTHDC1,BLOC1S6,GSDME,SPOCK3,SRGAP3,SGSM2,HS3ST2,RPS6KL1,DMTF1,FAM57B,PDCD6IP,GNE,DUSP9,ABCC9,GOLT1B,E2F6,EDNRB,SEMA3D,MBNL2,EGR3,EIF5,ELN,SEZ6,ENPP6,SPEG,TMEM74,EXTL1,F8,CLVS1,FCGR1A,CHST15,ZNF589,FGFR1,PRKAG2,MEX3B,SEMA4D,PSD2,PDLIM5,DACH2,STAU2,ABLIM2,MEGF10,GABRB3,SALL3,IP6K3,DISC1,ATP8A2,CPLX1,ALDH1L1,MALT1,AIFM3,GNAS,WDFY3-AS2,LILRB4,GPD2,GPR12,PCLO,GRIA2,GRIA4,PLCD4,ADAMTS13,ADAMTS8,GRM1,GSN,ZBTB49,MFSD2A,FAM107A,ADAMTS6,PADI2,PACSIN2,MAN1B1,ATXN2L,AGBL5,ZNF491,CELF5,FAM95B1,C2orf72,GAREM2,LRRCC1,BRINP3,DIPK1A,INSM1,ITPKB,KCNH1,KCNK3,KLRC3,L1CAM,LAMP2,HECTD2,NCOA7,GPR155,MAN2A2,ZFYVE27,MAOB,MDM4,MEIS1,MEIS2,MID1,PPM1L,XRRA1,DBNL,ADAM22,MT3,LAYN,RTL5,ZNF862,NCAM1,NF1,ALDH1L2,CHAMP1,OLR1,OPCML,SNTG1,DPY19L2P2,PIRT,PDGFRA,GPR173,NLGN3,TMIE,PIK3R1,ANKRD16,RC3H2,PPP2R5C,PPP3CB,PRKAB2,PRKACB,PRKCB,PKN2,PRKCZ,MAPK9,QRICH1,UHRF1BP1,BDNF-AS,MTMR10,ELOVL2,PTN,ZIK1,PTPRD,PEX5,ZNF844,CEP97,SLC25A48,ACSS3,OXR1,ARID4A,ZDHHC14,RET,RGS4,SEC61A2,SLC25A36,RIC8B,PBRM1,RNASEL,RNH1,LGI2,ARMC5,CCDC102B,FBXW7,BAALC,SPIN3,ATP8B4,S100B,DGLUCY,FOXRED2,MIR124-2HG,SEMA6D,SCN2B,SCN8A,FNIP1,FOXRED1,SH3GL3,FERMT1,MYO18A,NTNG1,ST6GAL1,SLC1A2,WDR47,SLC8A1,SLC12A4,SLC14A1,NAPB,SPHKAP,EPC1,NAXD,SMARCD3,LIMCH1,MBD5,SNRPN,UNC80,KDM4B,SOX5,BDP1,KDM3A,CAND2,HECW1,SPP1,KDM4C,KIF1B,IQSEC2,MCF2L2,RBM26,ITPRID2,MESP1,ZC4H2,NKAIN2,STAC2,ADHFE1,SULF2,NECAB1,FGD4,JMJD6,ADAMTS17,TAF6,WWC1,TBCEL,TBL1X,ANO4,VWA3A,TCF7L2,PHF24,USP32P1,CRB1,TIAM1,TMEM9,BHLHB9,LRRC8A,TMPO,RBFOX2,C9orf85,ELP5,TRIO,PPIL6,SSBP2,CLHC1,RPL7L1,UCHL1,SLAIN1,MGAT5B,MTCH1,CLIP2,LAT2,SF1,ZIC1,CFAP52,ZBTB38,ZNF177,ZFAND5,DNALI1,CIAPIN1,PCDH15,GAL3ST3,NAV3,PCBP4,PLSCR4,PARP11,HRASLS,PAK5,FBXO36,CAMK1G,FAM219B,JMJD1C,RNF170,FRMD6,IFT88,NETO1,GAN" MicroRNA hsa-miR-297:mirSVR_highEffct hsa-miR-297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.12E-130 2.88E-126 6.27E-129 5.77E-128 325 1322 "ACLY,CLK4,CSMD3,KLHL32,ADD3,CDC7,KIAA1211,KLHL13,OSBPL8,CC2D2A,C1QTNF3,LRRC7,ALCAM,ABCD2,MRTFA,CDC42BPA,ANK3,MAP4K3,ANXA7,API5,MIER1,NCOA1,INSYN2B,SLC4A4,EIF4G3,CADM3,ATP6V0A1,ADAM23,BMPR1B,SYNJ1,ARHGEF7,WASF1,CALB1,KALRN,CCKBR,KRIT1,LRBA,KCNAB3,TIGD7,CCPG1,CASC2,RAB33A,NRXN3,NRXN1,C4orf33,HECTD1,AKAP7,ARMC8,SLC25A27,COL9A3,SLC4A8,CNRIP1,CP,CLOCK,ABCG1,CSF1R,CSF2RA,OSBPL3,ATRNL1,NCAN,PDE4DIP,ERC2,CTNND2,MYADM,ARHGAP24,EARS2,DGKB,TMEM170A,TOMM20,DCC,MYEF2,CNIH3,SNAP91,SGSM2,GRIN3A,DRP2,PDCD6IP,SNX29,RASGRP1,EGFR,MBNL2,ABI2,COPS4,ELAVL2,PLEKHA1,C8orf37,CALCRL,SRRM1,VPS26C,EXTL2,F8,SH3YL1,ACSL4,FCGR3A,SLC9B2,KIAA1109,FGFR1,SUCO,CAP2,SYNCRIP,FLT1,PSD2,SLC37A3,TPK1,ATP6V1H,ZNF605,CELF1,STAU2,MEGF10,GABRB1,GABRB3,GABRG2,ILDR2,NCKAP1,C15orf41,DISC1,GATM,MSTN,SESN1,ADAM28,PPARGC1A,GK,TCERG1,CBX1,KIAA1958,GPM6A,GPM6B,ATF7,GRIA4,PLPP7,GRIK2,GRM7,BTN2A1,BVES,GUCY1A2,GYG1,HAS2,ZDHHC15,SMAP1,IFI16,ZNF546,DOCK7,PLD5,LIX1,INSM1,OLFM3,KCND2,KCNJ3,KIF2A,IPO5,STXBP5,INSYN2,NCOA7,PIK3AP1,MARK1,AQP11,MATN2,MATN3,LRP1B,MEIS1,MID1,ERICH3,MSR1,MSRA,SCG3,MX1,MYO9A,P2RY13,NELL1,NEUROD1,NEUROD2,NF1,NFE2L2,NRCAM,NTRK3,OLR1,OPA1,CLDN11,ETFRF1,PCSK2,PDE3B,BEST3,OLA1,NALCN,PIK3C2A,PIK3R1,ZNF655,A2ML1,XRN1,PLP1,STRN3,LRP12,PSAT1,EXOSC10,SPATA6,PPP2R5C,NKAIN4,GDPD1,SAMD9,MDGA2,QRICH1,PTAFR,ANKHD1,UHRF1BP1,BDNF-AS,PTPRE,PTPRG,ACSM5,DBX2,SLC6A15,ERI2,MORC4,FIGN,RFX4,RNF220,RIC8B,PBRM1,RNASEL,CCDC82,DCUN1D2,ROBO1,ROBO2,CCDC102B,RPE,MCMBP,GLDN,SYNDIG1,MEG3,CLIP1,ZNF354C,TRAPPC13,FAM192A,SEMA6D,LRRTM4,SCN8A,LINC00461,SCP2,ZFP2,HSPA4L,SGK1,FERMT1,NTNG1,FNDC3A,FHOD3,R3HDM2,ZNF365,SLC1A3,SLC6A8,RAB3GAP1,CCDC88A,ELMO2,BTBD7,ATF7IP,ZNF667,SMARCE1,RCOR3,RIMS1,SNAP25,MYO16,SOX5,KIF21B,BDP1,SOX15,TEX2,PEG10,MCF2L2,NPAS3,TAB2,CAMTA2,SSTR2,NKAIN2,NEK4,ADHFE1,KLHL7,PRRC2C,ADGRL3,ANO4,TCEA1,TCF4,DMXL2,TCF7L2,TCF12,SYNE1,PUM2,CRB1,AP4E1,HHIP,SLC44A1,ARL10,TMPO,CSMD1,TPM1,PRMT8,RUNDC3B,SSBP2,PITPNB,FLRT2,PLEKHH2,ZNF709,VLDLR,BEST1,NSD2,XRCC4,PCDH20,MICU3,ZNF28,ZBTB38,FSTL5,ANKS1B,PLPPR5,SYNC,CA10,EMSY,CADM2,PRDM2,RNF103,ADAMTS9,PCDH15,KCNAB1,FIP1L1,C12orf4,NUP214,KLHDC1,FRMD6,RNF146" MicroRNA hsa-miR-376c:mirSVR_highEffct hsa-miR-376c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.38E-130 3.02E-126 6.57E-129 6.05E-128 339 1437 "RALGAPA1,ABR,FAM43B,GALNT13,PWWP2A,KIAA1211,SLC44A5,PCDH19,TBC1D14,LRRC7,ALCAM,FAM135A,ALK,GPRASP2,OGT,ANK2,MAP4K3,CNIH2,PARG,APLP1,ASPH,NCOA1,N4BP2L1,NOL4,ATP6V0A1,DOCK11,SEC11C,SYNJ1,CACNA1G,OSGIN2,CA8,CACNA1E,CACNA2D1,CACNB2,CALB1,CALB2,KALRN,PTBP2,SLC25A14,VXN,CH25H,SPAG9,MAP7,CBLN1,CBS,INA,CD86,DGKI,ARHGAP33,LGI1,LOC730101,CCPG1,RCBTB2,SOCS6,CHN2,NDST3,QKI,MAP4K4,AKAP7,FAM149A,COL9A1,LETMD1,SLC4A8,RCHY1,TCEAL2,RTTN,MFSD4A,HS3ST5,FAM171B,CLOCK,CREM,SLC32A1,CSF2RA,FEZ1,MICAL2,SOCS5,ERC2,CTH,NRSN1,CX3CR1,DOCK4,HDAC9,TOX,KIF26A,PABPC5,DCT,HEPH,MFAP3L,BLOC1S6,ZC3H11A,GSDME,DDX46,SACS,SPOCK3,RABGAP1L,CCDC3,DLG2,DLX1,OLIG1,USP3,CPEB2,GNE,DTNA,MAMLD1,ABCC9,EDN1,ANKRD46,SGK2,FRY,FAM13A,PHF20L1,EGR3,PCOLCE2,C3orf18,EML1,EIF1,EN2,EPHA5,DENND4A,CDHR1,TMEM74,SIRPB1,FAM198B,TMEM132C,DLC1,TESK2,FGF14,PSD2,C2orf88,DACH2,NSG1,STAU2,MEGF10,GABRA1,GABRA2,GABRA5,GABRB1,GABRG2,CAB39,HBS1L,SALL3,ZNF274,SULT1C4,ARFIP1,COPS8,SPIN1,GPR75,GLS,MSL3,CBX1,INSM2,GPD2,GPM6A,GPM6B,TDRKH,NUDT21,PCLO,GRIA2,GRIA4,GRM3,GRM7,MFSD2A,SOX21,PSIP1,ATXN2L,MIER3,HNMT,HNRNPK,ICA1,IRF8,MSL1,ZNF546,NKD1,DIPK1A,INSM1,LRRTM3,KCNJ3,KCNJ16,KCNK1,SFXN5,SYTL4,NCOA7,CHIC1,TM6SF1,MEIS2,ZNF680,SAMD5,BLOC1S2,MSR1,ZNF92,MTTP,LYRM9,NAP1L1,NCAM1,NEFH,NEUROD1,SLCO1C1,NRCAM,HCN1,OPCML,PCSK5,PDE3B,PIRT,PDGFRA,GNG2,PFKFB2,NALCN,PIK3CD,ST8SIA5,PLP1,HMGCLL1,PURG,PMP2,TRHDE,ING3,EPB41L4B,NXPH1,MINDY2,PPP3CA,PPP3CB,PKN2,GRAMD1C,SYTL2,QRICH1,TMEM260,OCIAD1,C1orf109,PEX2,PPP2R3C,TMEM255A,USP47,ZNF493,ARID4A,MSANTD2,SLC6A15,ERI2,MORC4,RFX3,RIT2,NUDT11,RAVER2,ROBO1,RORB,PRR5L,LGR4,MEG3,CCDC112,RMI1,SATB1,ATXN7,SCN2A,FAM19A1,ELMOD1,IL17RB,CPEB3,NTNG1,CHD9,FNDC3A,DZIP1,DHX30,PKNOX2,SLC8A1,KBTBD4,BTBD7,SPHKAP,CPEB4,SORCS3,SMARCE1,RCOR3,LIMCH1,SNCB,MBD5,LMBRD1,PALLD,UNC80,KIF21B,BDP1,SPP1,KDM4C,ZNF423,KIF1B,TAB2,CLSTN2,LARP4,ERBIN,ZSCAN29,TTBK2,DIP2A,KANK1,FGD4,SYNE2,SYT1,COBL,ANKRD28,SYT4,DDHD2,DNMBP,ADGRL3,SATB2,RALYL,PCDHB10,TEK,FAM200B,DICER1,TGFBR3,TIAM1,BHLHB9,NR2E1,HEY2,RIMBP2,ZMYND8,RFTN2,SGK3,VLDLR,P2RY12,ETNPPL,XPO1,ZBTB14,ZNF711,ZNF708,FMN2,TCEAL7,CELF4,LRP8,EVI5,RNF103,PLSCR4,FAM13C,AMN1,DOCK8,KAT6A,PHTF2,JMJD1C,ZNF248,RNF170,MSRB3,KLHDC1,NETO1,ZNF30" MicroRNA hsa-miR-942:mirSVR_highEffct hsa-miR-942:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.00E-130 3.37E-126 7.31E-129 6.73E-128 384 1828 "AS3MT,NCKAP5,ACTN2,KDM5D,ADCY6,GALNT13,ADD1,KIAA1211,FAHD2CP,SLC44A5,GPR158,HECW2,CC2D2A,ADGRF5,SPOP,BCAR3,ARHGAP20,CARNS1,UNC79,LCORL,PPFIA1,APC,EPB41L5,LRRC4C,BCAS1,PPFIA3,TMEM263,SPTBN4,ASCL1,STK33,ASPH,INSYN2B,SLC4A4,ATP2B1,NOL4,ADAM23,MPDZ,SEC11C,PROM1,DST,SCAPER,CACNA1D,CACNA1E,LURAP1,KALRN,SYT6,CAST,CBR1,ZNF501,CBS,KRIT1,CCNH,SLC16A4,MAGI1,NOG,SRSF11,CHGA,SYNPR,IGFBP7-AS1,ZFYVE9,CLCN3,NRXN1,COG1,CLTA,HECTD1,AKAP6,COL4A5,SLC25A27,COL11A2,SLC4A8,SMARCAL1,IGDCC3,MFSD4A,HS3ST5,NECTIN3,SLC35F1,FAM171B,CDC42BPB,SH2B1,GDA,MROH8,SNCAIP,CSF2RA,SEC24C,SOCS5,VAC14-AS1,PDE4DIP,ERC2,CTNND1,NRSN1,ZSCAN23,DCAF4,BOC,TCAF1,ZFYVE16,LONRF1,TM9SF4,LIN54,MATR3,DGKB,AIF1L,ARMCX4,DCT,JAKMIP2,C8orf34,ZEB2,ZBTB24,HEPH,HP1BP3,DDX46,SPOCK3,NTM,WDR20,CHRDL1,EXOG,DMD,DNM1,HS3ST4,CPEB2,DMTF1,DSCAM,EDN3,SGK2,FCF1,FRY,YAF2,FAM13A,PHF20L1,KMT5B,EGR3,RASA4,TENM1,PAN3,IGSF6,ZNF391,CDKL3,RTN3,DNAJC27,HSPA12B,NRN1,CLVS1,FAM198B,RPS6KC1,DLC1,FGF1,FGF12,FGFR1,FLNC,ATP13A4,ZNF605,ST6GALNAC3,STAU2,GABRB1,GALNT15,GABRG2,TRAF3IP2,FAM120B,GALR1,ZNF559,DISC1,WASF3,CPLX1,MYOZ2,WASHC2A,PCDH17,HEPN1,GHR,CRCP,TCERG1,HPGDS,GLI2,TNRC6A,GNAL,GOLGB1,GPD2,GPM6B,LILRA1,PRLHR,NUDT21,RAPGEF4,STMN2,GRIA2,C1QL4,GRIA4,GRIK2,CLASRP,FAM19A2,AP4S1,SOX21,LINGO1,RNFT2,NXPH2,AGBL5,HSF2,CELF5,MSL1,IDH3A,ZIC5,LRRCC1,USP54,IL6R,INPP5B,NME9,ITGAM,KCNJ3,KCNJ16,KCNK2,KCNMA1,LIMS1,VWA5A,FGFBP3,PACRG,ZFYVE27,MBD1,MDM4,MEF2C,MEIS1,MEIS2,AFDN,MOG,CD200,GIT1,MSI1,BCO1,PTOV1,MYO9A,ZNF862,NCAM1,NEUROD1,NF1,OTOGL,NOVA1,SMIM11A,NTRK2,NTRK3,NUMA1,PAK3,PCDH9,PCSK5,CDK18,PDE3A,PDGFRA,GPR173,PFKFB2,PIK3C2A,A2ML1,SNX10,XRN1,PLCL1,PCDH18,ZNF426,RC3H2,MAGEL2,ING3,SEPT4,POLG,PPARA,PPP1R1A,PPP2R2C,LRRN3,PPP2R5C,PPP2R5E,KANSL1,PRKACB,EPDR1,MAPK10,HYDIN,SNRK,MDGA2,WDR25,PLPPR1,BDNF-AS,PTPRD,EML5,PTPRE,PTPRG,CCDC40,PLEKHB2,RASGRF2,RIT2,NUDT11,CCDC82,EXD2,C12orf49,ROBO2,RORB,YY1AP1,LGR4,ABCA11P,ATAT1,ZNF354C,RYR3,ATXN7,LRRTM4,TNFRSF19,SOX6,FNDC3A,SLITRK3,ST3GAL3,ANKRD6,ZNF365,FAM81A,SEPHS1,BTBD7,SLC22A4,RCOR3,ANKRD36,MBD5,KIF13A,SNRPN,UNC80,PDZD2,TNIK,DOK5,UHRF1BP1L,IDI2-AS1,DBNDD2,TAB2,PBLD,POGZ,NXT2,MAPK8IP3,STXBP1,NSFL1C,NECAB1,PLCB1,TMEM150C,SYT4,UNC5D,FBXW11,ANO4,ATMIN,WSCD1,TCF7L2,ZEB1,USP32P1,FRYL,RNF175,RNF216P1,TEK,DICER1-AS1,SPX,AP4E1,NR2E1,ERCC6L2,HEY2,RIMBP2,TPM1,METTL3,PRMT8,ELP5,TRIO,AMACR,TRO,TSN,ANO5,TTC3,RPL7L1,UBE2H,DNAJC12,LAT2,PCDH20,ZNF32,ZNF70,GPR158-AS1,CELF4,REEP1,ANKS1B,UPF3A,WNK1,LRP8,LMAN2L,PCDH15,NAV2,SLC17A7,FIP1L1,EPM2A,FAM13C,SMIM8,NHSL1,NETO1,DPF3,SLC4A10,SENP7" MicroRNA hsa-miR-4261:mirSVR_highEffct hsa-miR-4261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.19E-130 3.48E-126 7.44E-129 6.85E-128 363 1642 "RALGAPA1,SDE2,ABAT,KCNH8,EMILIN3,NCKAP5,ACTN2,CSMD3,ADAR,FMNL2,ADCY6,BRAP,SORCS1,PLEKHH1,MTA3,SLC44A5,PCDH19,ADGRF5,SPOP,ABCD2,UNC79,FAM135A,OGT,ANK2,SMIM29,PPFIA2,APLP1,CACHD1,USP37,SHTN1,ARNTL,ASPA,CAPRIN2,ASPH,B3GALT2,BCHE,GPR146,SYNJ1,FUBP1,CACNA1G,MMD2,DDR1,CACNB4,CALB1,KALRN,VXN,CAST,BRSK2,HIP1R,USP6,MAGI1,CHM,B4GALT6,JAM2,KMT2C,RAB33A,NRXN3,COG1,CLTA,TJP2,ABCG2,NIPBL,CNR1,CNTN1,PCYT1B,ARMC8,SUMF2,SLC4A8,CNRIP1,CP,FAM171B,CLOCK,CRMP1,HAPLN1,SLC32A1,ANKRD44,GDA,TRIM69,CS,SNCAIP,CSF3R,CSNK1E,FAM169A,DZIP3,PHF14,NRSN1,CX3CR1,CCDC144A,DOCK4,HDAC9,RIPOR2,DAPK1,SCRN1,JAKMIP2,FBXL5,CEP170,MAGI2,RHOBTB1,SRGAP3,G3BP2,WDR20,EXOG,OLIG1,ABCC9,EDIL3,SNX29,FAM135B,EDNRA,EDNRB,TMTC1,FSD1L,EFNB3,CELSR3,FAM13A,PHF20L1,SUGP2,MBNL2,KMT5B,AASS,COPS4,TMEM35A,STARD3NL,SEZ6,EPHA5,EPHB1,WAC,RACK1,FDFT1,GORAB,SPSB4,FGF12,BAIAP2,PRKAG2,SEC23B,CAP2,PCYOX1,AGAP2,SYNCRIP,IQCG,ANKFY1,ZCCHC17,SMC2,SPECC1,PDLIM5,TPK1,NPTN,KHDRBS3,NSG2,STAU2,PNMA2,MSANTD4,PHYHIPL,GABRA1,GABRA2,GABRA5,GALNT15,ZMYND11,GALC,JPH4,SESN1,GFER,GGT7,CRCP,DBF4,GLS,KDM2B,GNAL,PSRC1,ADGRA3,PRRC2B,PRUNE2,GPR12,EML4,PCLO,GRIA2,DIDO1,GRIK1,GRIK2,ADAMTS13,ZNF496,KIF3A,PTPN5,MFSD2A,RABL2A,ADAMTS6,ZHX1,NXPH2,SCRG1,HPSE2,GABARAPL2,NEGR1,IRF8,ITPKB,KCNMA1,KLC1,LAMP2,INSYN2,LMO1,SYTL4,SMAD1,PIK3AP1,MAP4,MAT2A,MBD1,MDM4,MEIS1,SRSF12,MIA2,WDR49,MOBP,ERICH3,MSI1,MTTP,MX1,FXYD6,NCAM1,SFR1,NELL1,NEUROD1,NEUROD2,NF1,SLC11A2,NTRK2,IGSF11,CHAMP1,GLIPR1L2,CNTN3,PCSK1,PDE3A,PDE4D,PDGFRA,HERC2P3,GDAP1L1,PLIN1,PLP1,ANKRD16,MAPKAP1,EPB41L4B,FA2H,POLR2F,TATDN3,CRLS1,PPP3CB,KANSL1,RASGEF1B,PRKACB,CEP41,PKIA,EPDR1,VPS13C,GDPD2,MDGA2,CNTLN,TMEM260,ZIK1,ZSCAN2,SH3TC2,ENOX1,RASGRF1,RASGRF2,FEZF2,MSANTD2,SLC25A36,PBRM1,RPRD1A,RAVER2,CARF,ROBO2,CCDC25,ELP2,PRR5L,TCP11L1,MEG3,ABCA11P,KCNIP2,KCNIP1,RXRG,TMEM156,SAFB,ATXN7,LRFN5,SCN2A,LRRTM4,LINC00461,SCP2,ITSN1,FERMT1,SHC4,MAGI3,CHD9,FHOD3,SYBU,ABLIM3,FAM81A,SLC2A5,SLC15A2,SPHKAP,TET1,EPC1,ZFP1,SORCS3,SMARCD3,MBD5,TMCC1,SP4,GLT8D1,EMC1,RBM26,TAB2,ATP10B,CLASP2,POGZ,SSTR1,SSTR2,LARP4,SEPT8,RGL1,ADHFE1,NECAB1,VAMP1,NUDT10,SYPL1,UNC5D,FBXW11,SMG6,TCF7L2,ZEB1,WASHC4,AKNA,GPRIN3,TEX15,ZFPM2,AP4E1,GZF1,ACTR6,DDHD1,TMPO,PRMT8,TSC1,PLEKHH2,ZIC3,MICU3,TRIM9,ZNF540,AGMO,NDRG4,ZSCAN26,PLPPR5,SLC30A4,STMN4,RNF103,NAV3,NAV2,MPPE1,PLSCR4,GOPC,FZD3,KAT6A,HNRNPA3,ADAMTSL3,SLC39A12,NETO1,DPF3" MicroRNA hsa-miR-548c-5p:PITA hsa-miR-548c-5p:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548h:PITA hsa-miR-548h:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548b-5p:PITA hsa-miR-548b-5p:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548a-5p:PITA hsa-miR-548a-5p:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548j:PITA hsa-miR-548j:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548i:PITA hsa-miR-548i:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-548d-5p:PITA hsa-miR-548d-5p:PITA_TOP PITA 6.21E-130 3.49E-126 7.44E-129 6.85E-128 261 844 "FMNL2,SLC12A5,ZNF608,GPR158,OSBPL1A,OSBPL8,FAM135A,LRCH2,C6orf89,LCORL,MAP4K3,PPP4R4,TMEFF1,ASCL1,CAPRIN2,BRINP2,ZBTB10,NCOA1,NUMB,SLC4A4,NOL4,ADGRB3,BCL2L2,DCAF5,JAZF1,SPAG9,KRIT1,INA,TMEM257,CD81,DLGAP2,CFL2,FOXN3,CHN1,LHX2,KMT2C,CLCN3,CLCN4,NRXN1,HECTD1,MAP4K4,CNR1,BTF3L4,SLC4A7,AHCTF1,CLOCK,CDC42BPB,C2CD2,CREB5,LRIG1,CSNK1E,CHD5,DZIP3,ERC2,PLCXD3,CTNND2,EDRF1,FRMPD4,ZFYVE16,MATR3,MAML1,TOMM20,ELMSAN1,C8orf34,RHOBTB1,SNAP91,SACS,SPOCK3,DLG3,RAB39B,DMTF1,DYRK1A,GOLT1B,EDIL3,YAF2,CELSR3,MBNL2,GOLGA7,PLEKHA1,CALCRL,PAN3,EPB41L2,RCAN2,ERBB2,EYA1,CACNG3,TAOK3,EFEMP1,ATP8A1,SEC24B,FGF12,PRKAG2,FOXG1,AFF2,NBEA,PDLIM5,STAU2,STAG2,MEGF11,GABRB3,CAB39,MTHFD2,C15orf41,GATM,MSTN,GK,PCDH11X,GNAO1,PRRC2B,GPD2,NUDT21,CECR2,RAPGEF4,GRB10,GRIA4,GRM5,CIT,IL1RAPL1,CELF3,HAS2,ATXN2L,MIER3,HNF4G,NEGR1,IGF1,C5orf24,INSM1,LRRTM3,ITGAV,KCNC2,KCNJ3,KIF2A,IPO5,LRRC4B,STMN1,SMAD1,MBNL1,LRP1B,MEIS2,KITLG,MKLN1,ERICH3,MYCN,HNRNPM,NEFM,NEUROD1,NOVA1,HCN1,NTRK3,IGSF11,PCDH9,PDE4B,PDE4D,GPR85,SERPINE2,NALCN,ZNF655,RETREG1,MED1,MINDY2,PPP2R5E,PPP3CB,PPP5C,PRKACB,CEP41,RAB39A,MAPK4,EPDR1,SNRK,PTCH1,PTK2,PTPRD,PTPRE,PTPRG,TTC13,CEP97,TMEM255A,RBBP8,REV3L,FIGN,RIC8B,RORB,CLIP1,RTN1,RYR3,ATXN2,SCN3A,FAM19A1,SOX6,TRA2B,DOCK10,CHD9,WDR37,ABLIM3,SLC1A3,BTBD3,WDR47,SLC8A1,CCDC88A,CPEB4,RIMS1,CABCOCO1,TMCC1,SON,SOX5,SOX11,SP4,KDM4C,PEG10,ARHGAP26,LMO3,SRPK2,CLASP2,ITPRID2,LARP4,SS18,RGL1,GSE1,NUDT10,ADAMTS17,PLCB1,SYT1,ATP11A,CAMTA1,CAMSAP2,FAM208A,TCF4,TRIM2,RPGRIP1L,TCF12,FRYL,AHCYL2,DICER1,SLC44A1,HEY1,HEY2,KAT6B,TPM1,TRPC1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,VLDLR,WIPF1,PCDH20,ZIC1,ZFAND5,PRDM10,ADAMTS9,PCDH15,NAV3,RGS7BP,FZD3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,FRMD6,RNF146" MicroRNA hsa-miR-624:mirSVR_highEffct hsa-miR-624:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.31E-130 4.67E-126 9.93E-129 9.15E-128 316 1252 "KLHL32,ADD1,SLC12A5,SORCS1,KIAA1211,DPY19L2P4,SLC24A4,MTUS1,PCDH19,AGT,RTL9,OSBPL1A,NME5,OSBPL8,FAM135A,SYT13,DPP10,LRCH2,LCORL,PKP4,APAF1,UPRT,TNRC6C,USP37,LGR5,MIER1,ARNTL,PDE8B,RASL11B,CHID1,ATP2B1,ATP6V1G2,ADAM23,CFLAR,BMPR1B,DST,SCAPER,SGCE,RAB29,CACNA1A,LURAP1,THSD7A,PTBP2,SYT6,VSTM2A,CAST,LDB2,USP6,USP2,MTMR7,SYNGR3,CD38,ZMYM4,CDH18,CACNA2D2,CFL2,SRSF11,SOCS6,CHM,CHN2,SYNPR,NRXN1,TMEM184B,NIPBL,ARMC8,AKAP6,COL9A1,RGS6,VAC14-AS1,PDE4DIP,PHACTR3,PLXNA4,DZIP3,ERC2,GREB1,PUM1,CCDC144A,DOCK4,HDAC9,KIAA0513,TM9SF4,LIN54,ARMCX4,DCC,ELMSAN1,ZNF804A,C8orf34,CEP170,RAB39B,OLIG1,DMTF1,DPH1,RCAN1,ECM2,MAMLD1,DYRK1A,PHF20L1,KMT5B,ELAVL2,CALCRL,VPS13B,ENPP6,SRRM1,DENND4A,CEP85L,ADGRV1,SCML2,TESK2,GORAB,FOXG1,VTI1B,SEMA4D,FLT1,EFCAB2,NBEA,SORBS1,UFM1,CELF1,PNMA2,FYN,MEGF11,GABBR1,GALNT15,ILDR2,ZMYND11,NCKAP1,ACSS1,LRRC37A6P,GATM,PPARGC1A,TCERG1,DBF4,TNRC6A,GLUL,PCDH11X,GPM6A,GRIA2,GRIA4,GRIK3,ADAMTS13,NR3C1,BVES,RASSF8,ARHGAP19,KLF12,LINC01102,HNMT,SMAP1,RBPJ,DOCK7,ZNF678,LRRTM3,JAK2,METTL21A,OLFM3,KIF5C,LAMP2,VWA5A,HECTD2,NCOA7,SMAD1,PIK3AP1,MARK1,MBD1,MBNL1,LRP1B,MEF2C,SRSF12,AFDN,MOBP,BLOC1S2,MSR1,RSPO2,MYO6,NAP1L3,NDP,SFR1,NEK1,NF1,NFE2L2,NOVA1,NTRK2,IGSF11,CHAMP1,OPA1,CNTN3,PBX1,PCDH9,PCSK2,PRTG,PDGFRA,PDPK1,PFKFB4,CDK14,ZNF655,XRN1,PLP1,ZNF426,PRIMPOL,PRRX1,PPP2R5C,PPP3CA,PPP3CB,KANSL1,PRKACB,EPDR1,PSMA6,QRICH1,ANKHD1,MTMR10,PTPRB,PTPRD,STRC,TMEM255A,FAT4,OXR1,RASGRF1,RASGRF2,ARID4A,RBBP6,ZYG11B,RFX3,RNASEL,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,RPE,TCP11L1,LRRK2,AP1AR,SALL1,SEMA6D,FNIP1,ITSN1,CPEB3,CHD9,BTBD3,DHX30,RUFY2,CCDC88A,SLC12A2,SLC15A2,ATF7IP,DMRTC1,SMARCD3,SNRPN,PALLD,TMCC1,SON,MYT1L,BDP1,FNBP1,DOK5,SP4,ZC3H13,MCF2L2,SPART,SS18,NXT2,MPRIP,STXBP1,SYT11,PRRC2C,VPS13A,SYT4,DNMBP,CAMSAP2,ADGRL3,DMXL2,SATB2,ZFP90,TCF7L2,WDR7,SYNE1,PCDHB4,PUM2,USP32P1,FRYL,VWCE,TEK,CRB1,AKTIP,ERCC6L2,TP53BP2,ZMYND8,RFTN2,ZKSCAN5,SGK3,FLRT2,XRCC4,ZFP37,ZIC3,ZNF28,ATP6V0E2,ZBTB38,ANKS1B,ZFAND5,PMEPA1,SLC38A1,LINC02210,PCDH15,FIP1L1,CAB39L,RGS7BP,FAM13C,MRPL47,RTN4,UBE3B,PAK5,CASC15,JMJD1C,RNF170,NETO2,NETO1" MicroRNA hsa-miR-3170:mirSVR_lowEffct hsa-miR-3170:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.73E-130 4.91E-126 1.04E-128 9.59E-128 362 1635 "TTYH1,KCNH8,ACLY,EMILIN3,ADCY2,DSCAML1,RNF157,ADD2,SORCS1,PWWP2A,KIAA1211,RNF150,ESYT2,BEND6,TAOK1,MARCH4,FAM135A,ZNF687,DPP10,ANK1,C6orf89,CNIH2,PPFIA1,APLP1,UPRT,ALS2,CACHD1,APP,CPNE5,AQP4,CDK10,TMEM263,ASCL1,ZBTB10,RASL11B,ATP1A2,RIPK1,BACH1,ADGRB2,SNAI3-AS1,BCL2L2,NRP2,KSR1,BMP7,ARHGEF7,CACNA1I,BTRC,CACNB4,KALRN,HAP1,SYT6,CAST,METTL6,MTMR7,LRBA,NUMBL,ASIC3,CHN1,C7orf61,EPS15L1,NMT2,TMEM59L,C4orf33,MAP4K4,LETMD1,COL11A2,SLC4A8,COX4I1,ZFP28,CLOCK,SH2B1,CS,CSF1,SEC24C,ARHGEF10,PLCH2,NCAN,SLITRK5,CMTM5,UBXN2A,CTH,NRSN1,PUM1,GPSM1,DCAF4,CX3CR1,MYADM,GAPVD1,ZNF337,MAML1,TOMM20,AIF1L,SIRPA,YTHDC1,JAKMIP2,ZBTB24,ELMO1,BLOC1S6,DDX46,POM121,ARNT2,DLG3,GRIN3A,DPH1,ATN1,DTNA,DYRK1A,ABCC9,FCF1,FRY,SIDT2,SH3GLB1,SUGP2,ELAVL4,ELN,C8orf37,VPS13B,EPB41,RABEPK,RASL12,CLVS1,NSRP1,FCGR3A,GTF2IRD2,FGF1,FGF11,FGR,FHL1,PCYOX1,AGAP3,SEMA4D,FLNC,C2orf88,EFCAB2,AKAP3,POMT1,UFM1,PDLIM5,STAMBP,ERGIC3,CGREF1,DLL3,ABLIM2,GAB1,GAD2,HBS1L,FAM120B,B4GALNT1,ZNF234,ERAP1,SYT17,LRRC37A6P,MYOZ2,GCK,GCNT2,SULT1C4,GFAP,GFRA2,GGT7,PPARGC1A,MALT1,MSL3,PCDH11X,GNAS,LNX1,LILRB4,GPR17,RAPGEF1,ADAMTS13,TMEM25,KAT7,RABL2A,ATOH8,IRAK3,MAEL,GPR45,ARHGAP19,HLF,ELOVL5,HMGB1,ZNF491,ZDHHC15,CPT1C,ATCAY,EID2B,FAM95B1,LINC00667,MYLK2,C5orf24,KNDC1,IL6ST,INPP5B,INSM1,ZNF385B,METTL21A,KCNJ10,KCNJ16,GATD1,CYP27C1,LAMP2,LIMS1,HECTD2,NCOA7,LSS,CLEC18A,ZNF667-AS1,MAN2A2,MAP6,MBP,CHST6,MDFI,MEIS1,SCAMP5,XRRA1,ZNF92,MYO7A,ZNF862,NCAM1,NEK1,NOVA1,NRCAM,ZNF827,ZDHHC22,PAK3,PCSK1,PENK,DUSP26,GPSM2,FTO,PCDH18,PLXNB3,MAPKAP1,PACSIN1,SH3KBP1,LRRN3,PPP3CB,NKAIN4,PROX1,SAMD9,MDGA2,UHRF1BP1,ELOVL2,PTPRD,FAM120C,PLEKHB2,ZNF793,SH3TC2,RASGRF2,DBX2,FEZF2,GTDC1,ZDHHC4,MRPS18A,KLHL11,RIC8B,DCUN1D2,PNMA8A,GSTCD,ROBO1,ROBO2,ROM1,SPIN3,KIAA0895L,SGSM1,STK32B,PTGR2,YJEFN3,KCNIP2,FAM192A,MAPK12,SCN2B,SCN4B,ASIC4,SELL,GALNT10,COPZ1,HKDC1,AMBRA1,CHD9,ST6GAL1,SLC1A3,PEX26,SMTN,KANSL3,SLC8A3,SIRT2,SLC12A2,NAPB,BTBD7,SLC22A4,TET1,CDK5RAP2,MYH15,IFT122,ANKRD36,MBD5,KIF13A,SNRPN,PALLD,TMCC1,SCN3B,KDM4C,PEG10,ZC3H13,IQSEC2,ZBTB43,NFASC,ATP10B,SSTR2,ZC4H2,FCHO1,ZSCAN29,CEP68,ADHFE1,KANK1,GSE1,FGD4,ARHGEF9,ANKRD28,TACR1,EXOC7,IQCE,SIN3B,ZFP90,SZT2,WDR7,SYNE1,NAT16,DOCK9,RALYL,PCDHB9,PUM2,CRB1,HHIP,FBXL16,TNFRSF1B,R3HDM1,TNS1,CDK20,TPM3,C9orf85,AMACR,UBTF,VIPR2,RICTOR,GUSBP1,ZIC1,ZNF19,ZNF24,DPYSL5,SMARCAD1,PRDM2,RGMA,PCDH15,WIPF2,C12orf4,CERS6,ADAMTSL3,PIANP,IFT88,NETO1,CBLN2" MicroRNA hsa-miR-96-5p:TargetScan hsa-miR-96-5p TargetScan 9.65E-130 5.42E-126 1.15E-128 1.06E-127 264 866 "ABAT,AS3MT,ADCY6,ADD3,PTCHD1,HECW2,KCTD16,KIAA1324,LRRC7,PCDH10,ALK,GPRASP2,OGT,CDC42BPA,LRCH2,PHF12,ARHGDIA,CDK13,PDE8B,MARCH3,BRINP2,NUMB,ASTN1,B3GALT2,DPY19L3,ADAM23,MTMR3,JAZF1,CACNA1G,NIPA1,CDK5R2,LDLRAD4,CACNA1B,CACNA2D1,CACNB4,PRC1,LDB2,INA,SCARB1,REPS2,EVI5L,LGI1,MAGI1,DLGAP2,CACNA2D2,FOXN3,RAB3C,QKI,MAP4K4,NIPBL,CNN3,COL9A1,MYRIP,IGDCC3,CLOCK,CDC42BPB,PREPL,AATK,LRIG1,RIMS4,PITPNM3,ERC2,APPL1,CTNND1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,ARHGAP24,FRMPD4,KIAA0513,KIF26A,RIMS3,KIAA0087,DNAL1,PLEKHM1,ELMO1,CEP170,RHOBTB1,KIF19,DSCAM,GNE,E2F5,EBF1,EDNRA,FEM1B,FAM13A,PHF20L1,MBNL2,ABI2,EGR3,EIF5,ELAVL2,ELAVL4,RGS17,PAN3,GPHN,RAB9B,ERBB4,NCALD,IGSF6,CEP85L,NRN1,ATP8A1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,NSG2,CELF1,NSG1,FUT9,FYN,PHYHIPL,GABRB1,GAD2,AHCYL1,BRPF3,B4GALNT1,NCKAP1,GAP43,GFRA1,FREM1,PCDH17,GK,AIFM3,GPM6A,GPM6B,GPR22,PCLO,RAPGEF4,GRIA1,PARD3B,GRID1,GRIK4,GRM5,GRM7,KAT7,ATOH8,RASSF8,HAS2,FRMD5,BACH2,C2orf72,CDH20,CLVS2,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,NAT8L,MBNL1,CHIC1,PPM1L,MITF,ADAM22,MYO9A,NCAM2,NF1,NOVA1,NOVA2,NPTX1,NPTX2,IGSF11,CHAMP1,OGDH,KCNK10,PAK3,PAX6,PC,PCDH8,PCMT1,PCSK5,CDK18,PDE4D,PDGFRA,GPR85,PIK3C2A,PIK3R1,FAM216A,PRRX1,MAGEL2,EPB41L4B,FAT3,MED1,PPP3CA,CEP41,PKN2,CNNM2,EML5,PTPRG,PTPRN2,CEP97,ATG16L1,ARID4A,BSDC1,RDX,PRIMA1,C12orf49,RAVER2,MCMBP,RIMKLA,FOXRED2,CSRNP3,ATXN1,SCN2A,SCN3A,MRAS,MAGI3,CCDC92,FAM81A,RPH3A,BTBD3,CCDC88A,ELMO2,ATF7IP,CPEB4,FAM126B,MYO16,FNBP1,NPAS3,RAP1GAP2,CLASP2,EPB41L3,LRRC4,PHLDB1,AJAP1,FAM168A,KLHL7,FGD4,JMJD6,COBL,CAMSAP2,FBXW11,DOCK9,ARHGEF12,GPRIN3,AP4E1,HHIP,CBX5,DDHD1,KCTD2,RUNDC3B,CADM1,BCL2L13,RICTOR,REEP1,PMEPA1,CADM2,EVI5,NAV3,FZD3,JMJD1C,FXR1,NETO2,GAN,LAS1L" MicroRNA hsa-miR-1271-5p:TargetScan hsa-miR-1271-5p TargetScan 9.65E-130 5.42E-126 1.15E-128 1.06E-127 264 866 "ABAT,AS3MT,ADCY6,ADD3,PTCHD1,HECW2,KCTD16,KIAA1324,LRRC7,PCDH10,ALK,GPRASP2,OGT,CDC42BPA,LRCH2,PHF12,ARHGDIA,CDK13,PDE8B,MARCH3,BRINP2,NUMB,ASTN1,B3GALT2,DPY19L3,ADAM23,MTMR3,JAZF1,CACNA1G,NIPA1,CDK5R2,LDLRAD4,CACNA1B,CACNA2D1,CACNB4,PRC1,LDB2,INA,SCARB1,REPS2,EVI5L,LGI1,MAGI1,DLGAP2,CACNA2D2,FOXN3,RAB3C,QKI,MAP4K4,NIPBL,CNN3,COL9A1,MYRIP,IGDCC3,CLOCK,CDC42BPB,PREPL,AATK,LRIG1,RIMS4,PITPNM3,ERC2,APPL1,CTNND1,CCDC144A,DOCK4,HDAC9,MYADM,GAPVD1,ARHGAP24,FRMPD4,KIAA0513,KIF26A,RIMS3,KIAA0087,DNAL1,PLEKHM1,ELMO1,CEP170,RHOBTB1,KIF19,DSCAM,GNE,E2F5,EBF1,EDNRA,FEM1B,FAM13A,PHF20L1,MBNL2,ABI2,EGR3,EIF5,ELAVL2,ELAVL4,RGS17,PAN3,GPHN,RAB9B,ERBB4,NCALD,IGSF6,CEP85L,NRN1,ATP8A1,MED12L,FGF14,AMOTL2,FHL1,FOXF2,FOXO3,FAM49B,CAMKK2,NSG2,CELF1,NSG1,FUT9,FYN,PHYHIPL,GABRB1,GAD2,AHCYL1,BRPF3,B4GALNT1,NCKAP1,GAP43,GFRA1,FREM1,PCDH17,GK,AIFM3,GPM6A,GPM6B,GPR22,PCLO,RAPGEF4,GRIA1,PARD3B,GRID1,GRIK4,GRM5,GRM7,KAT7,ATOH8,RASSF8,HAS2,FRMD5,BACH2,C2orf72,CDH20,CLVS2,KCNN3,CREG2,KIF5A,KTN1,L1CAM,LIMS1,NAT8L,MBNL1,CHIC1,PPM1L,MITF,ADAM22,MYO9A,NCAM2,NF1,NOVA1,NOVA2,NPTX1,NPTX2,IGSF11,CHAMP1,OGDH,KCNK10,PAK3,PAX6,PC,PCDH8,PCMT1,PCSK5,CDK18,PDE4D,PDGFRA,GPR85,PIK3C2A,PIK3R1,FAM216A,PRRX1,MAGEL2,EPB41L4B,FAT3,MED1,PPP3CA,CEP41,PKN2,CNNM2,EML5,PTPRG,PTPRN2,CEP97,ATG16L1,ARID4A,BSDC1,RDX,PRIMA1,C12orf49,RAVER2,MCMBP,RIMKLA,FOXRED2,CSRNP3,ATXN1,SCN2A,SCN3A,MRAS,MAGI3,CCDC92,FAM81A,RPH3A,BTBD3,CCDC88A,ELMO2,ATF7IP,CPEB4,FAM126B,MYO16,FNBP1,NPAS3,RAP1GAP2,CLASP2,EPB41L3,LRRC4,PHLDB1,AJAP1,FAM168A,KLHL7,FGD4,JMJD6,COBL,CAMSAP2,FBXW11,DOCK9,ARHGEF12,GPRIN3,AP4E1,HHIP,CBX5,DDHD1,KCTD2,RUNDC3B,CADM1,BCL2L13,RICTOR,REEP1,PMEPA1,CADM2,EVI5,NAV3,FZD3,JMJD1C,FXR1,NETO2,GAN,LAS1L" MicroRNA hsa-miR-610:mirSVR_lowEffct hsa-miR-610:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-129 5.84E-126 1.23E-128 1.13E-127 315 1245 "KLHL32,PLEKHH1,GRAMD1B,DPY19L2P4,AP2A2,RTL9,WDR35,PLA2G6,LRRC7,SMIM17,CEP126,ZFAT,OGT,ANK3,TNRC6C,APP,LGR5,CDC14B,SEMA4G,PLA2G4C,STK33,ASPA,ASPH,ATM,MTMR9,KIF1A,BCL2L2,KSR1,MTMR3,WASF1,BTRC,CA8,PTBP2,CBLN1,CD38,SEPT7,ZBED1,CDH18,LOC730101,PLEKHB1,CASC2,SYNPR,ZFYVE9,KIAA1549L,CLCN4,HECTD1,MAP4K4,IGLON5,AKAP7,PCYT1B,SUMF2,HAPLN1,SNCAIP,CSF1R,MICAL2,PITPNM3,UBXN2A,PNPLA8,CTH,RIMS2,ZSCAN23,DOCK4,KIAA0586,MAML1,IST1,TMEM170A,ARMCX4,PITPNC1,ELMSAN1,POM121,RHOBTB1,PLPPR4,SEC16A,CHRDL1,EXOG,CDON,CPEB2,DPP6,GNE,DNAJB6,EDN1,SYT15,CACNG7,PHF20L1,EGFR,KMT5B,AASS,EIF4G1,EIF5,C3orf18,C8orf37,DCTN4,VPS13B,F8,WAC,KIAA1109,FGF1,OLFM1,FHL1,SLC37A3,SORBS1,PDLIM5,STAMBP,CELF1,PHYHIPL,CHL1,GABRG1,ILDR2,ZMYND11,ARPP21,SEPT9,SRRM4,CPLX2,GGTA1P,GLI2,RAB30,TOX3,PCDH11X,LUZP2,GNAO1,GPD2,PRUNE2,CCDC184,GRM1,KIF3A,GSTM5,SOX21,GYG1,WIF1,C1orf94,SMAP1,LINC00667,ZIC5,RBPJ,LRRCC1,IGSF1,LIX1,IL6R,RIPPLY2,INSM1,LRRTM1,JAK1,JAK2,KCNJ11,KCNN2,KIT,KTN1,LIG4,FGFBP3,LOC100128239,MAP4,MAT2A,LRP1B,MEIS2,MIA2,PPM1L,AFDN,MN1,CD200,MXI1,MYO5A,NASP,NCAM1,NEUROD1,NF1,OTOGL,NOS1,DNHD1,CHAMP1,OPA1,CLDN11,TREM2,DPY19L2P2,GNG2,PFKFB2,GDAP1L1,NALCN,NOMO2,CCSER2,XRN1,FAM216A,ST8SIA5,FAT3,POLR2F,DRAM2,POU6F1,PPARA,PPP2R2C,PPP2R5E,PPP3CB,RANBP3L,RELN,LRRC49,TMEM260,ZIK1,C1orf109,PTPRZ1,PTX3,ZNF615,RAD51D,ENOX1,DBX2,ZDHHC14,MSANTD2,REV3L,RGS7,RIC8B,ALG9,RPE,ATP8B4,ACER3,TCP11L1,LRRK2,FAM182A,FOXRED2,LRRTM4,ELMOD1,ZFP2,IL17RB,PEAR1,SEC14L1,SGK1,SH3BP2,ITSN1,PPM1E,FERMT1,CPEB3,DOCK10,FHOD3,SYBU,NLGN1,DZIP1,BTBD3,EPN2,RUFY2,SLC6A1,PKNOX2,SLC8A1,NAPB,TET1,NAXD,GKAP1,SMARCC2,CDK5RAP2,SMARCD3,MAPKBP1,SOX5,ZCCHC24,CLUAP1,KIF1B,POGZ,COLGALT2,LARP4,SS18,CEP68,KANK1,AJAP1,FGD4,ADAMTS17,C3orf70,SLC37A2,SYT4,TACC1,ANKRD12,MTCL1,CAMSAP2,PDLIM2,TBCEL,TMEM136,TCF7L2,ZEB1,USP22,WDR7,ARHGEF12,HIF3A,LEFTY2,THBS4,ERCC6L2,TNFRSF1B,TPM1,C9orf85,SYNPO2,TRIO,PPIL6,SGK3,GORASP1,FRRS1L,FLRT2,ZNF709,BCL2L13,TOM1L2,BEST1,NSD2,RICTOR,PCDH20,ZIC2,GPR158-AS1,MKRN3,ZNF189,EMSY,EVI5,ADAMTS9,PCDH15,CAB39L,FZD3,ST7,UBE3B,KAT6A,CAMK1G,RNF170,SSPN,FXR1,GAN,FAM198A,SENP7" MicroRNA hsa-miR-1825:mirSVR_lowEffct hsa-miR-1825:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-129 6.61E-126 1.39E-128 1.28E-127 343 1474 "RALGAPA1,ASPHD1,KLHL32,PLEKHG5,ADCY2,CCDC85A,ADD3,PLEKHH1,ADORA1,HECW2,PCDH19,LRRC7,ARHGAP20,DOC2A,AMPD2,KIF6,ZFAT,ANK3,EP400,MAP4K3,PPFIA1,KCNAB2,DGKZ,GPAM,MIER1,CDK10,PDXK,SPTBN4,CDK13,BRINP2,NCOA1,NUMB,TMEM108,STX16,ATP2A2,MTMR9,ADGRB3,MPDZ,BCL7A,BMPR1B,CDK5R1,SYNJ2,FUBP1,LINC00906,CACNA1I,NIPA1,MMD2,CACNA1B,DDR1,HAP1,CAMK2A,CAPN3,SYT6,CH25H,SPAG9,CERS5,USP2,CBFA2T2,CD38,SEPT7,CDH8,DLGAP1,CCPG1,IGFN1,CLGN,NOG,UBE2L6,B4GALT6,RAB33A,CLCN4,SLC24A2,SULT4A1,SRP14-AS1,HECTD1,NIPBL,CNR1,AKAP7,IQCK,FAM149A,AKAP6,LETMD1,IFFO1,CS,PDE4DIP,PHF14,NRSN1,ST18,RUBCN,CCDC144A,CYBB,KATNAL2,FRMPD4,PHF19,DGKB,SPOCK2,AIF1L,B3GAT3,RUSC2,MAGI2,POM121,PLPPR4,SNAP91,SACS,TMCC2,WDR20,RAB39B,MED12,SLC29A4,SLC12A6,DUSP9,ABCC5,FRY,SIDT2,YAF2,SUGP2,EGFR,SORBS3,ELAVL2,EML1,PAN3,ERBB2,REEP2,EFEMP1,FCGR1A,TESK2,MED12L,KIAA1109,TMEM164,AKAP3,NBEA,SORBS1,TMEM107,APOPT1,ATP2C1,ZNF605,NSG1,GABRA1,HBS1L,JPH4,GHDC,GAP43,SIGLEC8,DISC1,DNER,TUBA8,SRCAP,ARFIP1,AHDC1,ADAM28,PPARGC1A,TTBK1,TCERG1,TOX3,GLUL,AIFM3,STARD3,MAP7D2,INSM2,RAB40B,GRB10,ADAMTS13,GRM2,FAM19A2,RNF165,WIF1,NCKAP1L,HLF,CPT1C,OPALIN,DHX35,SHISA6,HTR5A,C5orf24,IGFBP1,KIAA1755,IL11RA,KCNJ16,KCNK3,SFXN5,PAXBP1,HECTD2,ARHGAP12,C2orf80,ZFYVE27,MBNL1,CHIC1,MDM4,MEIS1,MKLN1,NAP1L1,NEFM,NELL1,NEUROD1,NFYA,CNOT4,NOVA1,DNHD1,SLC11A2,HCN1,ODF2,LOC100128398,CDK18,PDE2A,PDYN,BEST3,PIK3CD,SNX10,PKM,GPSM2,NLE1,FAM216A,PLP1,PURG,PRIMPOL,C11orf49,PMP22,RETREG2,SH3KBP1,PPARA,PPP2R5E,PKIA,PRKCB,PRKCZ,MAPK4,EPDR1,GRAMD1C,SLC22A23,GON4L,PIGG,PTHLH,PTK2,TMEM260,OCIAD1,RIPOR1,TUG1,PLEKHB2,RIC8B,PBRM1,RNASEL,ARMC5,ROBO1,ELP2,TMEM100,EPHA10,BAALC,ZC3H14,SGSM1,KCNIP2,CLIP1,RXRA,SATB1,CSRNP3,HOGA1,SCN8A,SCP2,SOX6,TRIM46,FOXRED1,ASRGL1,SUPT20H,AMBRA1,FBXO11,R3HDM2,NUBPL,PAAF1,BTBD3,WDR47,FAM214B,KANSL3,ZNF430,SLC9A5,CPEB4,SMARCC2,RCOR3,RIMS1,SNCA,SNRPN,TMCC1,USP33,CLUAP1,EMC1,TEX2,IDI2-AS1,ZBTB43,DDN,STOX1,EPB41L3,LRRC4,INKA2,GSE1,ACSBG1,PRRC2C,ABCC8,PLCB1,SYT4,ANKRD12,MTCL1,EXOC7,EHBP1,TCF4,ZFP90,ZEB1,TRIM2,DOCK9,FRYL,DNAH7,DICER1,SIRT1,ZFPM2,CRB1,AP4E1,MTMR14,TMEM9,RELL2,TMPO,TPM2,TRO,FNDC5,DCBLD1,TST,TTC3,CLHC1,UBTF,OSBP2,SLC13A3,TRIM9,SLC26A10,EML6,SPIRE1,SMARCAD1,UPF3A,CADM2,PRDM2,DNALI1,STOX2,FAM47E,C12orf4,GOPC,FAM13C,FZD3,CASC15,FXR1,NETO2" MicroRNA hsa-miR-136:mirSVR_highEffct hsa-miR-136:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.22E-129 6.85E-126 1.44E-128 1.33E-127 345 1491 "AS3MT,CSMD3,ADCY6,CCDC85A,ADD1,ADD3,SORCS1,PWWP2A,KIDINS220,ZNF608,INTS2,RTL9,WDR35,CC2D2A,SPARCL1,ALCAM,AMPH,LRCH2,MAP4K3,PHF12,PPFIA2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,GPAM,PPFIA3,ZFYVE28,ARNTL,CADPS,MARCH3,STK33,N4BP2L1,BACH1,RGS11,DCAF5,JAZF1,CACNA1G,CACNA1E,CALB1,KALRN,CAMK2D,CAMK2G,MAP7,NFS1,ZNF501,INA,DGKI,LRBA,DLGAP1,CCPG1,CACNA2D2,SRSF11,SYNPR,NDST3,CLTA,FBXO7,CNTN1,AKAP7,ARMC8,FAM149A,COL4A5,AKAP5,ABI3BP,ACBD5,SEC31B,SH2B1,SNCAIP,RGS6,OSBPL3,SIPA1L1,VCAN,CTH,GREB1,ARHGEF4,CX3CR1,NOS1AP,KATNAL2,GAPVD1,EARS2,DGKG,IP6K1,DNAJC6,ZEB2,C2CD2L,DDX46,ALKBH8,POM121,RHOBTB1,SACS,NTM,RABGAP1L,WDR20,CCDC3,HS3ST4,USP3,CPEB2,DMTF1,DTNA,GOLT1B,AASDH,SGK2,SEMA3D,TMTC1,FSD1L,EFNA3,APH1A,EBI3,MBNL2,COPS4,EML1,TUBD1,EPB41,EPHA5,IGSF6,MRVI1,F8,ABCA8,ACSL4,CHST15,ZSCAN30,FDFT1,GORAB,SUCO,CAP2,FLT1,SGIP1,NELFCD,UFM1,PDLIM5,TPK1,CGREF1,ST6GALNAC3,MEGF10,GABRA2,TRAF3IP2,JPH4,ARPP21,NEK6,MTHFD2,WASF3,GATM,IGSF5,NEU3,GCNT2,SESN1,ADAM28,USP19,GGTA1P,PPARGC1A,LYVE1,GK,GLS,TNRC6A,ZNF638,KDM2B,GNAS,GPT2,STMN2,GRIA1,PLCD4,GRID1,PRDM5,GRM5,TMEM25,RNFT2,KLF12,MIER3,ZDHHC15,SMAP1,ZNF181,ZNF546,ZIC5,IGSF1,IL6ST,ITGAM,KCNJ4,SYTL4,NCOA7,MARK1,IL17D,SRSF12,MID1,AFDN,XRRA1,BLOC1S2,CTNNA3,MYT1,NDUFA5,NEK1,NF1,CNOT4,NOVA1,NTRK2,OLR1,DPY19L2P2,PCSK5,PDE3B,CYTL1,SEMA5B,ZNF655,PMP22,STRN3,LRP12,SPATA6,MBOAT7,SH3KBP1,PPP2R5E,MASP1,SNRK,WDR25,PIGG,CNTLN,ELOVL2,TMEM260,PTPN13,PTPRE,PTPRG,TTC13,FAM66C,RAP1GDS1,OXR1,ARID4A,KHDRBS2,TRIM68,GTDC1,RFX3,RGS4,KLHDC8A,CARF,ARMH4,UEVLD,GLDN,LRRK2,RYR3,SCN2A,LRRTM4,ZFP2,CASC3,ITSN1,KIF16B,FBXO11,CNKSR2,NUBPL,SLA,ZNF365,SLC1A3,BTBD3,SEPHS1,RADIL,RAB3GAP1,ARHGEF40,CCDC88A,SLC12A2,SLC12A4,SLC14A1,NAPB,SLC15A2,ATF7IP,RCOR3,SON,TRERF1,TNIK,BDP1,HECW1,ZNF423,C11orf87,SRPK2,PBLD,POGZ,ZNF302,ZC4H2,NKAIN2,NXT2,NECAB1,FGD4,SUPT5H,PRRC2C,SYP,SYT1,ATP11A,CAMTA1,CAMSAP2,ADGRL3,ANO4,EHBP1,TCF7,TCF7L2,ZEB1,RPGRIP1L,WASHC4,SYNE1,DOCK9,RALYL,AHCYL2,RNF216P1,ITGB3BP,AKTIP,NR2E1,ERCC6L2,KAT6B,TPD52,NPL,TPM3,METTL3,PRMT8,TTTY15,TMEFF2,CADM1,UBE2H,UBE3A,PITPNB,PLEKHH2,VLDLR,WIPF1,ZNF781,WRN,ZFP37,ZIC3,ZNF23,MICU3,ZNF28,ZNF32,ZNF138,EML6,SPIRE1,SYNC,WNK1,SLC30A4,PRDM2,PRTFDC1,PRDM8,PCDH15,NAV3,KCNAB1,PDSS2,MARCH8,UBE3B,PAK5,KAT6A,PHTF2,JMJD1C,TRAM2-AS1,ZNF248,MSRB3" MicroRNA hsa-miR-922:mirSVR_highEffct hsa-miR-922:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-129 1.50E-125 3.15E-128 2.90E-127 341 1461 "ABR,NCKAP5,ACTN1,NDRG3,SLITRK1,BRAP,PWWP2A,FAHD2CP,AP2A1,SLC44A5,GPR158,PCDH19,KIAA1324,SMIM17,FAM135A,AMPD3,AMPH,OGT,ANK3,PHF12,SUGT1P4-STRA6LP-CCDC180,APBB1,GPAM,NT5C3B,API5,MIER1,ARHGAP5,RGS20,CCDC74A,ZBTB10,ATP2A2,ATP2B1,ALDH7A1,N4BP2L1,DPY19L3,ADGRB3,CFLAR,ST3GAL5,ARHGEF7,NIPA1,CA8,CACNA1B,CACNB2,CALB1,CALM1,PTBP2,CAMK2D,SYT6,CH25H,CDC42,CDH10,DCLK1,ZMYM4,CDH18,MS4A7,MAP4K4,IQCK,AKAP6,LETMD1,TOGARAM2,ZFP28,FAM171B,GDA,TRIM69,CSF1R,MICAL2,CSNK1G3,SOCS5,PDE4DIP,DZIP3,UBXN2A,NRSN1,ST18,DCAF4,RUBCN,CYBB,GPRASP1,FGFR1OP2,KATNAL2,LONRF1,IST1,DGKB,BRINP1,DNAJC6,PLEKHM1,MYEF2,GSDME,SACS,G3BP2,TMCC2,HS3ST2,USP3,CPEB2,DSCAM,GNE,ABCC5,HIPK3,CNNM1,CELSR3,PHF20L1,APH1A,EBI3,GOLGA7,EN2,VPS13B,ENPP6,SRRM1,CDHR1,ETV1,RCSD1,ADGRV1,NRN1,F8,TAOK3,FER,BAIAP2,EVL,NELFCD,EFCAB2,PDLIM5,STAMBP,NPTN,CELF1,CGREF1,CSPG5,OGA,GABRA2,CAB39,ARPP21,DISC1,TUBA8,GGT7,GJB1,DHRS4,GK,GLS,TNRC6A,PCDH11X,INSM2,KCNMB4,GNAS,GPD1,GPM6B,CCDC184,STON1,EML4,GRB10,GRIA2,NR3C1,GRM7,RNF165,ADAMTS6,MAP4K5,ARHGAP36,HLF,VSIG4,AGBL5,MSL1,PLD5,IL11RA,KCNC2,KCND3,KCNJ3,KCNK1,KCNK2,KCNMA1,LAMP2,PAXBP1,SYTL4,NCOA7,MAP4,MAPT,MBD1,MBNL1,LRP1B,MEIS2,MN1,ERICH3,MRPL42,MTTP,MYBPC1,NCAM1,NCF2,NPTX1,NRCAM,SMIM11A,HCN1,NTRK2,NUCB2,NUMA1,GPR137C,PAK3,PDE3B,BEST3,NALCN,NOMO2,PIK3R1,PLEC,TRHDE,STRN3,ING3,MED1,PPP2R2B,MAPK9,GRAMD1C,PSD,WBP1L,SYTL2,SNRK,CNTLN,PTHLH,TMEM260,ZSCAN32,ZIK1,OCIAD1,PTPRD,ZSCAN2,RAD51D,ZNF493,RADX,BSDC1,RDX,FIGN,RGS4,SEC61A2,SLC25A36,ALG9,ROBO2,ELP2,FBXW7,ATP8B4,CNTNAP3,KCNIP1,FAM192A,AP1AR,SAFB,SCN3A,SCN8A,LINC00461,PRCD,SCP2,ELMOD1,CASC3,ASRGL1,COPZ1,SH3GL2,FERMT1,CPEB3,NLGN1,ST3GAL3,SEC31A,WDR37,SLC1A3,CCDC88A,SLC12A2,ATF7IP,CPEB4,CDK5RAP2,IFT122,SNCA,MBD5,FAM126B,RBM34,SON,WDTC1,KIF21B,BDP1,CLUAP1,EMC1,SPART,LMO3,C11orf87,TAB2,ST5,ZSCAN29,ELOVL4,SEPT3,ARHGEF9,VPS13A,SYN2,SYP,MMS19,ATP11A,CAMTA1,MCF2L,ADGRL3,TBCEL,SYNE1,SLC19A3,TGFBR3,HHIP,GZF1,TIAM1,NACC2,DDHD1,HEY2,TMPO,C9orf85,TRIO,RUNDC3B,DCBLD1,KCNE5,ZKSCAN5,CLHC1,TMEFF2,CADM1,UCHL1,PITPNB,CCDC14,TBC1D15,P2RY12,NSD2,WNT7A,SF1,ZIC3,ZNF711,ZNF24,MKRN3,REEP1,ANKS1B,SH3GLB2,SMARCAD1,SYNC,PRDM2,PRDM10,CAB39L,MVB12B,RGS7BP,FZD3,DOCK8,PHTF2,CASC15,TIGD6,RNF170,SNX14,SLC39A12,IFT88,DPF3,RNF146,FAM198A,JPH3" MicroRNA hsa-miR-3132:mirSVR_lowEffct hsa-miR-3132:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.73E-129 1.54E-125 3.21E-128 2.96E-127 323 1313 "ASIC1,CLK4,C3orf14,CSMD3,NDRG2,PLEKHG5,GALNT16,CCDC85A,ADD1,SORCS1,ADRB2,MTA3,SLC24A4,AP1B1,SNX32,OSBPL1A,KIAA1324,WDR35,CC2D2A,TAOK1,ALCAM,GPRASP2,MRTFA,CDC42BPA,C6orf89,CCDC146,PHF12,PPFIA2,APAF1,UPRT,SHROOM2,AQP6,SFMBT2,PRX,TMEFF1,NUMB,CHID1,ATP1A1,EIF4G3,CADM3,ATP6V0A1,TTLL9,BBS2,BCHE,MIR9-3HG,ZNF599,BMP7,ARHGEF7,SCAPER,GYG2,CACNA1I,RAB29,CDK5R2,CACNA1B,CALB2,PTBP2,NGB,PRC1,ARHGEF1,TMEM257,DGKI,LRBA,SEPT7,SOCS6,SYNPR,NDST3,CPNE6,COG1,SRP14-AS1,HECTD1,AKAP7,IQCK,AKAP6,SLC4A7,AHCTF1,HINFP,ABCG1,CRYM,CS,CSF1,SUSD5,CST3,KIAA0040,UBXN2A,ST18,DCAF4,SEC14L5,GAPVD1,FRMPD4,RIMS3,DGKG,AIF1L,GIT2,ZEB2,ZBTB24,COPS7A,KLHL3,PLPPR4,SV2B,SRGAP3,SGSM2,FAM107B,GRIN3A,RAB39B,SHANK1,E2F5,E2F6,EDNRB,HEYL,RASGRP1,EFNA3,PHF20L1,APH1A,EIF4G2,SORBS3,TENM1,CALCRL,DCTN4,GPHN,ARMCX1,NSRP1,ZIC4,TUBB4A,CORO2B,EFEMP1,CHST15,FCGRT,KAT8,POLR1B,FGF11,SPSB4,FGF14,PRKAG2,CAMSAP1,SUCO,HPCAL4,FOXF2,TMEM107,APOPT1,ATP6V1H,CELF1,ADGRA1,ZNF44,CHL1,GAD1,ACSS1,GATM,GFAP,GFER,MMADHC,USP19,DBF4,ZNF638,PSRC1,GPD1,SPACA9,ADAMTS8,GRM7,GRM8,CIT,COQ10A,ZBTB45,HAS2,ELOVL5,SYNPO,ZDHHC15,SHISA6,FAM95B1,GAREM2,IL6R,LRRTM3,OLFM3,KCNC1,KCNH1,KCNH2,KCNMA1,GATD1,TTYH2,MAN2A2,MAT2A,MEIS1,MN1,MOBP,MPP2,MSR1,NRBP2,CTNNA3,SAMD14,MXI1,MYO7A,NDUFA5,NFYA,NHLH1,NINJ2,NME4,NOS1,NOVA1,DNHD1,LRIT2,NTRK2,IGSF11,GPR88,OPCML,PCSK5,CDK18,PDE2A,PDE1B,GNG2,GDAP1L1,ZNF655,GPSM2,FAM216A,PLEC,HMGCLL1,LRP12,SH3KBP1,POU3F2,RASGEF1B,EPDR1,WBP1L,LRRC49,TMEM104,PIGG,CNTLN,ELOVL2,ZIK1,OCIAD1,PTPRD,PTPRO,TUG1,RASGRF1,ZDHHC14,UBR7,SLC25A36,ARMC5,CCDC25,UEVLD,STK32B,WLS,RTKN,YJEFN3,CLIP1,DGLUCY,ATXN2,SOX6,CASC3,GALNT10,CPEB3,MYO18A,AMBRA1,SMTN,LIMS2,PKNOX2,SLC22A4,MAST1,SNRPN,PDZRN3,SCN3B,DOP1A,SOX5,UNC5B,IQSEC2,TSPYL2,RBM26,C11orf87,SRPK2,CAMTA2,SSTR1,ZC4H2,RGL1,DNAJC9,C3orf70,SYP,TACR1,EXOC7,UNC5D,TCF7,TCF7L2,RPGRIP1L,ARHGAP9,AHCYL2,RNF216P1,TF,TGFBR3,AKTIP,ARL10,DAAM2,TPD52,NPL,TPM3,WBP2,SMUG1,TRPM2,PPIL6,CA14,PRR18,BCL2L13,PLPPR2,TOM1L2,WIPF1,LAT2,LGI4,TRIM9,FMN2,MKRN3,SPHK2,ZBTB38,REEP1,SPIRE1,ZFAND5,SMARCAD1,PRDM2,CSDE1,STOX2,GAL3ST3,SLC17A7,WNK3,EPM2A,DOCK8,PHTF2,JMJD1C,PIANP,ST8SIA2" MicroRNA hsa-miR-378:mirSVR_lowEffct hsa-miR-378:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-129 1.74E-125 3.64E-128 3.35E-127 363 1650 "SERPINA3,CLK4,SYS1,KDM5D,GPRIN1,ADAR,ADCY2,CCDC85A,TMCC3,ADD2,ADD3,ADORA1,ADORA2A,RNF150,PTCHD1,KIDINS220,MTA3,AP2A2,SNX32,PCDH19,C1QTNF3,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,APBA2,KCNAB2,VAT1L,PPFIA3,SPTBN4,ARNTL,MARK4,ASPH,NUMB,DNAJC27-AS1,KSR1,GYG2,CACNA1G,RAB29,MMD2,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,VXN,SYT6,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,IGFN1,GPR37L1,SOCS6,CASC2,MYL6B,NMT2,ABCG2,CNGA3,FHL5,IQCK,FAM149A,COL4A5,ABI3BP,MFSD4A,CHD1L,CLOCK,HAPLN1,CRYM,SNCAIP,TENM4,ATRNL1,NCAN,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,EDRF1,ARHGAP32,HDAC4,INTS1,IST1,DGKG,SIRPA,SPATA2,DNAJC6,ZEB2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLG2,DLX1,RAB39B,OLIG1,DNM2,DMTF1,PDCD6IP,EDN1,FAM135B,SGK2,RASGRP1,SUGP2,MBNL2,SORBS3,IRAK4,PLEKHA1,TMEM35A,EN2,VPS13B,EPB41,SEZ6,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,CACNG3,PTK2B,ZSCAN30,SEC24B,MED12L,FGR,SUCO,PCYOX1,AGAP3,PSD2,ZCCHC17,ZBED3,APOPT1,NSG2,KBTBD12,B3GAT1,NRG3,DKK3,CAB39,FAM184B,BRPF3,GALC,RAPGEF6,IP6K3,GAP43,DISC1,INPP5K,SRCAP,ADAM28,GGTA1P,ZNF638,CBX1,DCLK2,GPM6B,RAPGEF4,GRIK2,GRM7,CLASRP,IL1RAPL1,BVES,IRAK3,LINC01102,SYNPO,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,LIX1,IL6R,TMEM240,KCND1,KCNJ3,KCNJ10,KCNK1,KCNN3,KLC1,L1CAM,HECTD2,MAT2A,AQP11,SYT9,MEF2C,AFF1,CCDC80,MSR1,PTOV1,MXI1,MYO7A,RTL5,ZNF862,HNRNPM,NCF2,NELL1,VWA2,NOVA1,DNHD1,CLEC9A,NTRK3,NUMA1,GPR88,PCDH9,PDCD2,PDE4A,PDE1B,TMOD2,PFKFB4,NLGN3,ZNF655,CCSER2,XRN1,SLC25A23,CDIP1,RC3H2,PPARA,PPM1B,CRLS1,PPP3CA,PPP3CB,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,FAM120C,PEX2,PEX5,SUSD4,NWD1,RAP1GDS1,RASGRF1,ERI2,RFX5,PRIMA1,KCTD17,RNF220,CARF,GSTCD,PCMTD2,SNX22,RPL15,SPIN3,KIAA0895L,GLDN,TCP11L1,SYNDIG1,ABCA11P,AP1AR,MAPK12,ATXN2,SCN2A,PEAR1,SOX6,CASC3,ZNF821,SH3BP2,PPP1R9A,NTNG1,MAGI3,ANKRD6,PAAF1,EPN2,SLC6A1,PKNOX2,LRRC55,SLC8A2,SLC8A3,ARHGEF40,SLC20A2,SPHKAP,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,WDTC1,ZCCHC24,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SMOC1,SSTR1,LARP4,APOM,SEPT8,ADHFE1,STX1A,ARHGEF9,SYN2,ANKRD28,MMS19,DDHD2,MCF2L,DNMBP,FBXW11,ANO4,TBX15,SIN3B,TCF7,TCF7L2,TCF12,WDR7,AKNA,TEK,FAM200B,ZNF34,SLC44A1,ARL10,DAAM2,TNFRSF1B,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,ELP5,AMACR,TRPC1,DCBLD1,RUSC1,KCNE5,ANO5,RFTN2,TUB,CLHC1,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,SF1,KCNT2,LYPD6,SH3GLB2,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,NUP214,VANGL2,SSPN,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-153-3p:TargetScan hsa-miR-153-3p TargetScan 3.46E-129 1.94E-125 4.05E-128 3.73E-127 226 623 "ABAT,ASIC2,ARID1A,ADD1,GPR158,HECW2,KCTD16,OSBPL6,DOC2A,ANK1,ANK3,APBB2,APC,APP,CASK,ARNTL,CDK13,PCDHGB4,ATP2A2,ATP2B2,CADM3,ADAM23,DCAF5,BSN,LDLRAD4,CACNA1B,CACNB4,CAMK2G,CANX,RUNX1T1,CCNT1,DCLK1,MAGI1,DLGAP2,CFL2,CHM,CLCN3,CLCN4,NMT2,CLTC,QKI,CNN3,IQCK,AKAP6,RCHY1,BAG4,C2CD2,CREM,CREB5,CRMP1,PLXNA4,CCDC144A,FRMPD4,ELMSAN1,PLEKHM1,MFAP3L,KLHL3,DLG2,DLX1,DMD,CALN1,CDON,CPEB2,DYRK1A,FAM135B,HIPK3,KLHL5,FSD1L,EFNA3,ELAVL2,ELAVL4,RGS17,KCNMB2,GPHN,RASL12,SCML2,ATP8A1,CHST15,FOXO3,NBEA,NPTN,CAMKK2,ATP2C1,DOT1L,FYN,GAB1,FAM184B,PPARGC1A,KDM2B,FERMT2,GPR37,PCLO,RFFL,GRIK2,GRIK3,GRIK4,ADAMTS8,RNF165,MAP4K5,FRMD5,BACH2,MIER3,HNRNPK,C5orf24,SCRT2,KCNA1,KCNA4,KCNA6,KCNB1,KCND1,KCNK3,KCNQ3,KPNA5,LIMS1,PAXBP1,MAT2A,MATN2,MEF2C,KCTD6,SCAMP5,MITF,AFF1,MOV10,JAKMIP3,MYO5A,NCAM2,NEFM,NEUROD1,NEUROD2,NF1,NFIA,NFE2L2,NFYA,NOVA1,HCN1,KCNK10,PCDHGC3,PCDH8,PDE3B,PDE4D,PIK3R1,CCSER2,MTRF1L,LRP12,FAT3,PPP3CA,KANSL1,PRKAB2,PRKACB,PKN2,MAPK4,EPDR1,PROX1,MDGA2,PTCH1,PXK,PTPRD,OXR1,RASGRF2,ARID4A,ERI2,FIGN,RIC8B,LGI2,ROBO2,KCNIP2,RYR3,SATB1,ATXN7,SCN3A,SCN8A,FAM102A,PKNOX2,ARHGEF40,BTBD7,CPEB4,EPC1,GKAP1,NMNAT2,HECW1,RBM26,NFASC,CLASP2,FAM168A,PLCB1,DMXL2,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,PCDHA7,CRTC1,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CBX5,HEY2,FAM124A,PITPNB,FLRT2,RICTOR,KCNK12,EML6,DPYSL5,LAMP5,CADM2,PRDM2,NAV3,NAV2,RGS7BP,FZD3,FXR1,GAN" MicroRNA hsa-miR-1244:mirSVR_lowEffct hsa-miR-1244:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.56E-129 2.56E-125 5.32E-128 4.90E-127 367 1687 "ACLY,CLK4,ACTN1,KDM5D,SLC25A25,ADCY2,CCDC85A,ADD3,BRAP,GRAMD1B,SLC44A5,RTL9,TBC1D14,NME5,WDR35,CC2D2A,SPARCL1,SPOP,ALCAM,UNC79,USP28,GPAM,ARNTL,CADPS,MARK4,DACT3,CCDC181,SLC4A4,ATP2B1,BCL7A,NRP2,FUBP1,OSGIN2,RAB29,LDLRAD4,CACNB4,KALRN,PTBP2,VSTM2A,SPAG9,MAP7,MTMR7,DCLK1,LARGE1,ZNF445,DLGAP2,CCPG1,LRWD1,JAM2,RAB28,NRXN3,PPT2,KIAA1549L,MAP4K4,LY86,LETMD1,SLC4A8,ZFP28,CREM,RNF14,ANKRD44,OSBPL3,ATRNL1,SIPA1L1,PHACTR3,CNTNAP2,SLITRK5,DZIP3,KIAA0040,PNPLA8,EDRF1,GAPVD1,SNPH,DCAF8,RASSF2,LIN54,MAML1,ARMCX4,ZNF804A,MFAP3L,KLHL3,RHOBTB1,CCDC3,GRIN3A,DNAH9,NR1D2,DRP2,DTNA,ECM2,ABCC5,EDN1,ATL1,SGK2,CNNM1,RBM12,PHF20L1,SUGP2,KMT5B,AASS,IRAK4,DCTN4,LRRC17,SRRM1,ERBB4,IGSF6,ETV1,PIPOX,F3,WAC,TOMM40L,FKTN,MED12L,KIAA1109,OLFM1,SYNCRIP,ATP13A4,EFCAB2,TACC2,TMEM107,PDLIM5,ZNF605,HHIPL1,NRG3,DKK3,GAB1,GABRA1,GABRA3,ILDR2,ACSS1,GCNT2,TUBGCP4,GDF9,TCERG1,TOX3,MSL3,PRUNE2,LILRA1,EML4,TPPP,GRIA1,GRIK2,NR3C1,GRM5,GRM7,KIF3A,ZBTB49,AP4S1,ADAMTS6,FRMD3,HLF,GABARAPL2,AGFG1,HSP90AA1,TJAP1,LIX1,IL6R,ITGAV,JAK1,JAK2,KCNJ3,KCNK1,KCNMA1,KIF2A,KTN1,INSYN2,LMO2,VWA5A,ARHGAP12,GPR155,MAN2A2,MAP2,MAP4,SYT9,TM6SF1,MDM4,KCTD6,PPM1L,AFF1,MMP16,MSR1,MXI1,LAYN,NAP1L2,NEUROD1,NEUROD2,SLCO1C1,NHLH1,DNHD1,SETD4,IGSF11,ODF2,OPHN1,P2RX7,GPR137C,PDE3B,PDE4B,PFKFB3,OLA1,PIK3R1,ZFYVE21,GPSM2,NLE1,FTO,ZNF426,MAPKAP1,SCHIP1,RETREG2,SEPT4,FA2H,FAT3,NXPH1,PPM1B,PPP2R5C,RANBP3L,RASGEF1B,PRKACB,HYDIN,BCAS3,MDGA2,PIGG,UHRF1BP1,NCR3LG1,PTPRD,PTPRO,FAM120C,TUG1,MARCH1,CEP97,RAP1GDS1,ARID4A,RBBP6,MSANTD2,RGS3,PRIMA1,ARHGEF10L,SEC61A2,RNF220,RIC8B,RNASEL,LGI2,RERGL,ROBO1,RORB,ZC3H14,GLDN,ACER3,CNTNAP3,PTGR2,KCNIP3,WLS,FAM192A,SATB1,LRRTM4,SCN8A,SOX6,KIF27,RASA3,SCAF8,ITSN1,FERMT1,CPEB3,SHC4,CNKSR2,BCAN,NLGN1,CTXN2,PAAF1,SLA,SLC1A2,SLC2A5,RAB3GAP1,SLC8A3,ARHGEF40,SLC14A1,ATF7IP,SLCO1A2,SMARCC2,CDK5RAP2,SMARCE1,LIMCH1,RIMS1,SNCA,MBD5,PALLD,TMCC1,UNC80,DOP1A,SOX2,ZCCHC24,BDP1,MYCBP2,KIF1B,RBM26,LMO3,C11orf87,SSTR1,ZC4H2,ADHFE1,SEPT3,GSE1,FAM168A,ACSBG1,FGD4,C3orf70,ANKRD28,TACR1,MTCL1,TCF4,SIN3B,DMXL2,ZFP90,ZEB1,TRIM2,TCF12,SYNE1,DOCK9,ARHGEF12,GPRIN3,C18orf54,AP4E1,HHIP,AKTIP,SLC44A1,TPD52,TPM4,PRMT8,TRPC3,ANO5,TTTY15,TUB,TMEFF2,SGK3,TUBB1,ZNF610,DNAJC12,PITPNB,FLRT2,MTCH1,BEST1,RICTOR,GUSBP1,XPO1,CFAP298,ZNF24,MKRN3,ZBTB38,ANKS1B,SMARCAD1,DHX33,WNK1,PRDM2,SLC38A1,PARP6,NAV2,KCNAB1,WIPF2,RGS7BP,DNAH10,FAM13C,MRPL47,PAK5,PHTF2,ADAMTSL3,JMJD1C,TTC7A,CBLN2,SOCS4" MicroRNA hsa-miR-558:mirSVR_lowEffct hsa-miR-558:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.88E-129 3.30E-125 6.85E-128 6.31E-127 357 1601 "ABCF1,ASIC2,KLHL32,PLEKHG5,TMCC3,RNF157,BRAP,ESYT2,PTCHD1,PCDH19,OSBPL6,SPARCL1,FAM135A,ZNF687,PITPNM2,AMPH,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,TNRC6C,SHTN1,AQP4,KIAA1614,ARNTL,ALDH4A1,ATM,CCDC181,ZNF583,SLC2A11,RIPK1,TTLL9,ADGRB3,RGS11,GPR146,ZNF599,SCAPER,MTMR3,MTMR2,CACNA1I,CFAP410,CACNB2,CALB2,CABP7,CAMK2G,CANX,RUNX1T1,CBR1,INA,ARHGEF1,DGKI,CDH8,CLGN,SRSF11,KMT2C,EPS15L1,RAB28,STOML1,FAM19A5,TMEM155,CNTN1,AKAP6,SUMF2,RTTN,MFSD4A,CLOCK,PREPL,CSNK1E,OSBPL3,GALNT9,VAC14-AS1,CST3,FAM169A,ERC2,PHF14,RUBCN,CCDC144A,DCAF8,KIAA0513,MAML1,TOMM20,IP6K1,DBN1,ARMCX4,DCC,YTHDC1,RUSC2,ZC3H11A,SV2A,SRGAP3,NTM,TMCC2,WDR20,SEC16A,ZNF582-AS1,DLG2,DLG3,GRIN3A,HS3ST2,DPH1,DTNA,TOM1,AASDH,EDN1,EDN3,EDNRB,PHC2,SGK2,HIPK3,FAM13A,GPR61,TMEM132E,RASA4,ASB3,MRNIP,BSCL2,TUBD1,VPS13B,MFSD10,RCAN2,EPHA5,CDKL3,SIRPB1,CACNG3,TUBB3,FCGR1A,FCGR3A,FKTN,SLC9B2,FER,BAIAP2,AGAP2,WDR83,TACC2,FAM49B,NPTN,CAMKK2,PRELID3A,TBR1,GABRB1,FAM184B,HBS1L,RAPGEF6,SEPT9,DNER,GATM,SULT1C4,ARFIP1,GPR162,GFAP,LYVE1,RND1,GLRB,MSL3,LILRB4,GPD1,GPD2,MCHR1,ZNF496,CIT,GSN,KAT7,MFSD2A,PSIP1,WIF1,UBE2QL1,MAN1B1,HLF,HMGB1,NEGR1,OPALIN,LRRC75A,MYLK2,RBPJ,KNDC1,LRRCC1,KIAA1755,TJAP1,DISP2,SCRT2,IL11RA,KCNA1,KCNMA1,STMN1,VWA5A,FGFBP3,NCOA7,LSS,MAN2A2,MGAT3,GIT1,COMMD5,MX1,MYL3,NAP1L1,NCAM1,NEFM,NELL1,NELL2,NEUROD1,VWA2,LRIT2,SLC11A2,NRGN,NUMA1,ZNF827,PCDH9,ENPP2,TMEM38A,ST8SIA5,PLXNB3,PRIMPOL,ANKRD16,PMP22,STRN3,LRP12,EPB41L4B,FSD1,PPM1B,CRLS1,PPP2R5E,PRKACB,MAPK4,MAPK10,GDPD1,SLC22A23,APTX,SIDT1,GON4L,TMEM104,QRICH1,CNTLN,MTMR10,PTHLH,TMEM255A,USP47,CCDC40,RBBP6,DPF2,RET,MRPS18A,RIC8B,TMLHE,KLHDC8A,CARF,CYB561D1,CCDC25,NEK11,KIAA0895L,ABCA11P,KCNIP3,YJEFN3,FAM192A,SAFB,SALL1,ATXN2,PRCD,HES6,TNFRSF19,ZNF821,PPM1E,AMBRA1,DHX30,SLC8A1,SLIT1,ABTB1,SMARCA4,CDK5RAP2,MYH15,MBD5,SOX2,BDP1,SOX15,KDM3A,ZSWIM8,NMNAT2,CLUAP1,MYCBP2,KDM4C,IDI2-AS1,PEG10,NKAIN2,NXT2,DIP2A,PHLDB1,VPS13A,C3orf70,ANKRD28,TACR1,MCF2L,TBL1X,SATB2,ZEB1,TPCN2,AZIN2,SYNE1,DOCK9,PCDHAC2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,DNAH7,SIRT1,SPX,GALNT17,ZFP91,ERCC6L2,HEY2,DAAM2,RIMBP2,TNFRSF1B,TNS1,RBFOX2,RASD2,NPL,SYNPO2,TRIO,STXBP4,TRPM2,ZMYND8,FNDC5,KCNE5,TMPRSS5,UBE2H,OSBP2,BCL2L13,MEAF6,VLDLR,BEST1,GUSBP1,ZNF19,ZBTB16,AMZ1,DPYSL5,FTSJ1,ZFAND5,SMARCAD1,SYNC,PRDM2,SLC38A1,STMN4,RNF103,SEMA3B,PCDH15,NAV2,WNK3,MVB12B,MARCH8,NUP214,FAM219B,NLRP3" MicroRNA hsa-miR-181a:PITA hsa-miR-181a:PITA_TOP PITA 6.02E-129 3.38E-125 6.98E-128 6.43E-127 256 817 "CPNE2,KCNH8,SLC25A25,FMNL2,TMEM132B,SLITRK1,CCDC85A,SLC12A5,ERMN,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,ANK1,GAS7,API5,CDC14B,SEMA4G,MADD,CAPRIN2,DDX3Y,SLC4A4,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,ADGRB3,DCAF5,JAZF1,WASF1,FOXK1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,SYNPR,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,TENM4,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,TOX,LONRF1,CTIF,ELMSAN1,MFAP3L,BLOC1S6,ZC3H11A,POM121,SPOCK3,G3BP2,MTX3,WDR20,ARNT2,NR1D2,CDON,DPP6,DPYSL2,ABI1,PDCD6IP,E2F5,ST8SIA3,KLHL5,FSD1L,MBNL2,EGR3,ELAVL2,PAN3,EN2,EPS8,NCALD,CLVS1,ZIC4,DLC1,ATP8A1,MEX3B,PCYOX1,SYT3,NPTN,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GPR22,CECR2,RAPGEF4,GRB10,GRIA2,GRIK2,NR3C1,GRM5,CIT,ADAMTS6,WIF1,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,DOCK7,KCNC2,KCNMA1,IPO5,LIFR,LMO1,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,RSPO2,HS6ST3,NEXMIF,ZC3H12B,NEFH,OTOGL,CNOT4,NOVA1,HCN1,IGSF11,GPR88,GPR137C,KCNK10,PCSK1,PRTG,PDE3B,PDGFRA,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,FAT3,POU3F2,PPARA,PPP2R5E,CEP41,PROX1,CNNM2,PTPRE,FAM120C,USP47,FIGN,RFX2,PRIMA1,TTLL7,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,ATXN1,FNIP1,SOX6,SCG5,ITSN1,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,PALLD,TMCC1,FAM126B,DOP1A,SOX5,NMNAT2,RBM26,LMO3,SRPK2,CAMTA2,EPB41L3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,GSE1,PRRC2C,MTCL1,UNC5D,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,PSD3,SLC35G2,SIRT1,THBS4,HEY2,TNS1,NR2C2,PITPNB,SF1,ZIC2,ZIC3,ZNF28,SMARCAD1,WNK1,SEMA3B,PAK5,PHTF2,SOCS4,SLC4A10" MicroRNA hsa-miR-181c:PITA hsa-miR-181c:PITA_TOP PITA 6.02E-129 3.38E-125 6.98E-128 6.43E-127 256 817 "CPNE2,KCNH8,SLC25A25,FMNL2,TMEM132B,SLITRK1,CCDC85A,SLC12A5,ERMN,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,ANK1,GAS7,API5,CDC14B,SEMA4G,MADD,CAPRIN2,DDX3Y,SLC4A4,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,ADGRB3,DCAF5,JAZF1,WASF1,FOXK1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,SYNPR,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,TENM4,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,TOX,LONRF1,CTIF,ELMSAN1,MFAP3L,BLOC1S6,ZC3H11A,POM121,SPOCK3,G3BP2,MTX3,WDR20,ARNT2,NR1D2,CDON,DPP6,DPYSL2,ABI1,PDCD6IP,E2F5,ST8SIA3,KLHL5,FSD1L,MBNL2,EGR3,ELAVL2,PAN3,EN2,EPS8,NCALD,CLVS1,ZIC4,DLC1,ATP8A1,MEX3B,PCYOX1,SYT3,NPTN,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GPR22,CECR2,RAPGEF4,GRB10,GRIA2,GRIK2,NR3C1,GRM5,CIT,ADAMTS6,WIF1,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,DOCK7,KCNC2,KCNMA1,IPO5,LIFR,LMO1,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,RSPO2,HS6ST3,NEXMIF,ZC3H12B,NEFH,OTOGL,CNOT4,NOVA1,HCN1,IGSF11,GPR88,GPR137C,KCNK10,PCSK1,PRTG,PDE3B,PDGFRA,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,FAT3,POU3F2,PPARA,PPP2R5E,CEP41,PROX1,CNNM2,PTPRE,FAM120C,USP47,FIGN,RFX2,PRIMA1,TTLL7,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,ATXN1,FNIP1,SOX6,SCG5,ITSN1,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,PALLD,TMCC1,FAM126B,DOP1A,SOX5,NMNAT2,RBM26,LMO3,SRPK2,CAMTA2,EPB41L3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,GSE1,PRRC2C,MTCL1,UNC5D,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,PSD3,SLC35G2,SIRT1,THBS4,HEY2,TNS1,NR2C2,PITPNB,SF1,ZIC2,ZIC3,ZNF28,SMARCAD1,WNK1,SEMA3B,PAK5,PHTF2,SOCS4,SLC4A10" MicroRNA hsa-miR-633:mirSVR_highEffct hsa-miR-633:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.70E-129 3.76E-125 7.76E-128 7.15E-127 351 1550 "SDE2,KCNH8,ACADM,ABHD6,NBAT1,KLHL32,TMEM132B,GALNT13,SLC12A5,SORCS1,ERMN,PWWP2A,KIAA1211,INTS2,GPR158,HFM1,C1QTNF3,SPARCL1,SMIM17,ABCD2,LRCH2,CCDC146,GPAM,SHTN1,ASPH,B3GALT2,ADAM23,BMPR1B,NAE1,CALB1,CAMK2G,VXN,PRC1,KRIT1,CCNH,USP6,INA,C1orf52,DGKI,LRRFIP1,CIART,COPB2,CHM,B4GALT6,JAM2,NDST3,ZFYVE9,ABCG2,C4orf33,NIPBL,CNN3,AKAP6,COL4A5,SLC4A8,ABI3BP,AHCTF1,MYRIP,ZNF521,ZFP28,IGDCC3,CP,CPS1,FAM171B,PREPL,HAPLN1,FEZ2,LRRC3B,APPL1,PNPLA8,CTH,NRSN1,EDRF1,CYBB,TOX,PHF19,LONRF1,LIN54,KIAA0586,ZNF804A,C8orf34,MYEF2,RUSC2,KIAA0319,CEP170,BLOC1S6,NR1D2,CPEB2,DTNA,ABCC9,E2F5,EDN1,ATL1,RASGRP1,FSD1L,PHF20L1,MBNL2,KMT5B,DCTN4,VPS13B,EPB41,EPB41L2,LRRC17,EPHA5,DENND4A,NCALD,ZNF391,ANKMY1,F5,FAM198B,WAC,TMEM132C,DLC1,FCGR1A,KIAA1109,OLFM1,MEX3B,PCYOX1,FLT1,ATP6V1H,ATP2C1,DACH2,DLL3,MSANTD4,FYB1,GABRA1,CHL1,CAB39,ILDR2,RAPGEF6,SYT17,DISC1,KIAA1841,DNER,PPARGC1A,HPGDS,SPIN1,GLRB,KCNMB4,FERMT2,LNX1,GPM6B,STON1,NUDT21,PCLO,GRIA2,GRIA4,GRM1,GRM5,RNF165,ZBTB49,PSIP1,MAP4K5,RASSF8,ZHX1,FRMD5,TNFAIP8L3,MIER3,HLF,ELOVL5,HMGB1,GABARAPL2,HNF4G,HNMT,ZIC5,RBPJ,DOCK7,LRRCC1,USP54,INSM1,JAK2,OLFM3,KCNA4,KCND2,LAMP2,LIG4,MATN2,MATN3,MBNL1,LRP1B,SRSF12,MEST,MIA2,MKLN1,XRRA1,BLOC1S2,MSR1,NAP1L3,NEK1,NEUROD1,NF1,SLCO1C1,NFE2L2,NFIX,CNOT4,NOVA1,NRCAM,NTRK2,IGSF11,LOC100128398,OPRL1,GPR137C,GLIPR1L2,SLC10A4,BEST3,CDK14,SNX10,RETREG1,PLCL1,PCDH18,PMP2,MAPKAP1,STRN3,LRP12,SEPT4,POU3F2,DRAM2,LRRN3,RAB39A,MAPK9,GDPD1,VPS13C,SNRK,CNTLN,MTMR10,ELOVL2,SPDL1,TMEM260,PTPRB,C1orf109,PTX3,CEP97,PLEKHB2,RAD52,FAM66C,SH3TC2,FAT4,RAP1GDS1,DBX2,ZNF532,TMLHE,ROBO1,ROBO2,RORB,RPE65,NEK11,SPIN3,TRAPPC13,RMI1,SCN2A,LRRTM4,SCN7A,SLC30A10,SEC14L1,GALNT10,CHD9,FBXO11,CNKSR2,NLGN1,SEC31A,DZIP1,WDR37,RUFY2,RAB3GAP1,CCDC88A,SLC14A1,MTERF2,BTBD7,NAXD,SORCS3,LIMCH1,UNC80,SON,MYT1L,BDP1,KDM3A,UHRF1BP1L,MCF2L2,RBM26,LMO3,SRPK2,ITPRID2,STOX1,NKAIN2,STAU1,ZSCAN29,ELOVL4,NEK4,TTBK2,KANK1,SULF2,AJAP1,NECAB1,PRRC2C,VPS13A,FNDC9,SYT1,COBL,ANKRD28,CAMTA1,TBCEL,ACSL6,VWC2,SZT2,PCDHB10,PCDHB7,PCDHAC2,USP32P1,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,TIAM1,DDHD1,BHLHB9,ERCC6L2,BEX4,NR2C2,STXBP4,TMEFF2,TUBB1,UBE2H,UBE3A,P2RY12,WNT7A,SLC47A2,ZNF711,MICU3,ZNF74,ZNF184,EML6,EMSY,CADM2,PRDM2,LINC02210,STOX2,PRDM10,ADAMTS9,PCDH15,SLC17A6,PLSCR4,C12orf4,EPM2A,MRPL47,CASC15,NHSL1,IFT88,CBLN2" MicroRNA hsa-miR-21:mirSVR_lowEffct hsa-miR-21:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.63E-129 4.85E-125 9.98E-128 9.19E-127 340 1458 "ACLY,BRAP,SORCS1,KIAA1211,SNX30,ADRB2,GPR158,PCDH19,ALCAM,PCDH10,FAM135A,GPRASP2,SYT13,USP28,PKP4,EPB41L5,GPAM,ALS2,APOC1,PDXK,ASCL1,STK33,MARK4,ASPH,NUMB,TMEM108,RNF182,DOCK11,TTLL9,BCHE,DCAF5,NAE1,CACNA1G,CACNA1E,CACNB4,CACNG1,CALB1,THSD7A,USP6,LGI1,L3MBTL4,CDO1,COPB2,RAB28,ZFYVE9,CLCN3,CLTC,CNN3,AKAP7,FAM149A,WHRN,AKAP5,ACBD5,MYRIP,HS3ST5,CHD1L,RBM39,AKAP12,RNF14,ANKRD44,LRRC3B,CSNK1G3,SDC3,APPL1,PLCXD3,PNPLA8,NRSN1,RUBCN,EDRF1,NOS1AP,KIAA0408,HDAC9,TCAF1,ZFYVE16,LONRF1,TBC1D5,MATR3,SCRN1,ARMCX2,MFAP3L,HP1BP3,DDX46,POM121,RHOBTB1,SMG7,SPOCK3,SV2A,DLG2,DLX1,HS3ST2,MED12,DMTF1,SLC12A6,ACOT8,ECM2,DNAJB6,ABCC5,E2F5,EBF1,SNX29,FAM135B,ATL1,KLHL5,FRY,OPTN,EGFR,EGR3,COPS4,VPS13B,ZIC4,FCGR1A,SLC9B2,MED12L,PRKAG2,CAMSAP1,FOXG1,FOXM1,FOXO3,ANKFY1,SLC37A3,EFCAB2,NBEA,STAMBP,KHDRBS3,DACH2,CSPG5,FYB1,HRASLS5,TRAF3IP2,HBS1L,RAPGEF6,C15orf41,GATM,GCNT2,SESN1,GGTA1P,RUNDC3A,GLYR1,MSL3,GLUL,PCDH11X,ZNF638,LOXL3,FERMT2,ADGRA3,GPD2,GPR34,GRM7,BTN2A1,BVES,AP4S1,ATOH8,TMEM179,HAS2,HPS5,ZHX1,NCKAP1L,ACOT7,HMGCR,EID2B,MSL1,ZIC5,USP54,ZNF678,ITGAM,CDH20,KCNJ3,KCNJ10,KCNK1,KCNK2,STMN1,VWA5A,PIK3AP1,MARK1,MBD1,MBP,CHIC1,SHC3,MEF2C,MEIS2,KCTD6,MOG,MSR1,RSPO2,LAYN,MYO6,NAP1L3,NCAM1,NEK1,NF1,NFIA,NOVA1,NTRK2,NUMA1,OLR1,OXTR,KCNK10,PAK3,ETFRF1,PCDH8,PCSK2,PDE3A,PDE4D,PFKFB2,SERPINI1,PIK3R1,FAM218A,CCSER2,PLP1,SLC25A23,LRP12,MBOAT7,IRX1,MINDY2,PPP2R5E,PRKAB2,RASGEF1B,PRKCB,PKN2,PIGG,PTK2,PTPN13,OCIAD1,PTX3,TUG1,PID1,FAM66C,FAT4,FAM184A,NWD1,OXR1,RBBP6,KHDRBS2,ZDHHC14,BSDC1,RDX,RET,ERI2,FIGN,RGS10,SEC61A2,RNASEL,TMLHE,ROBO2,ELP2,CCDC102B,MRAP2,SPIN3,ZNF568,CCDC112,SCN7A,SCN8A,SOX6,SH3GL3,PPM1E,SHC4,NLGN1,CTXN2,DZIP1,SLC1A3,WDR47,KANSL3,LRRC55,SLC6A11,KBTBD4,SLC12A2,ZFP1,SMARCE1,MBD5,SNRPN,FNBP1,SP4,GLT8D1,HECW1,CDK19,ZBTB43,NPAS3,LMO3,TAB2,ZNF621,SSTR2,ZC4H2,ST5,ELOVL4,CEP68,PHLDB1,STXBP1,NSFL1C,KLHL7,NECAB1,JMJD6,PRRC2C,PLCB1,SYPL1,DDHD2,CNTN2,TMEM136,ANO4,CUX2,RPGRIP1L,WDR7,RALYL,PCDHB6,RNF216P1,CRB1,TGFBR3,GZF1,TMEM9,ACTR6,ZFP91,HEY2,CSMD1,TP53BP2,METTL3,SSBP2,CLHC1,SLC35A4,CLDND1,SLC13A3,XPO1,ZNF24,FMN2,ZNF74,ZBTB38,REEP1,FSTL5,EML6,SMARCAD1,INTS3,EMSY,CADM2,SHD,PCDH15,FAM47E,MVB12B,SMIM8,PHTF2,JMJD1C,FXR1,NETO2" MicroRNA hsa-miR-422a:mirSVR_lowEffct hsa-miR-422a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.30E-128 7.32E-125 1.50E-127 1.38E-126 369 1710 "SERPINA3,CLK4,SYS1,KDM5D,GPRIN1,ADAR,ADCY2,ADCY6,CCDC85A,TMCC3,ADD1,ADD2,ADD3,ADORA1,ADORA2A,RNF150,PTCHD1,KIDINS220,MTA3,AP2A2,SNX32,PCDH19,SPARCL1,PCDH10,GPRASP2,ZNF687,AMPD2,AMT,CDC42BPA,APBA2,KCNAB2,DGKZ,VAT1L,PPFIA3,SPTBN4,ARNTL,MARK4,ASPH,NUMB,MTMR9,DNAJC27-AS1,KSR1,ARHGEF7,GYG2,MMD2,CFAP410,CACNB4,KALRN,PTBP2,CAMK2A,VXN,SYT6,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,GPR37L1,SOCS6,CASC2,NMT2,ABCG2,CNGA3,FHL5,FAM149A,COL4A5,ABI3BP,MFSD4A,CHD1L,CLOCK,HAPLN1,CRYM,TENM4,ATRNL1,NCAN,VAC14-AS1,UBXN2A,ZSCAN23,EDRF1,ARHGAP32,INTS1,SIRPA,SPATA2,DNAJC6,ZEB2,ZBTB24,TMEM130,SV2B,WDR20,DLG2,DLX1,RAB39B,OLIG1,USP3,DNM2,DMTF1,PDCD6IP,EDN1,FAM135B,SGK2,RASGRP1,SUGP2,MBNL2,SORBS3,IRAK4,PLEKHA1,MRNIP,TMEM35A,EN2,VPS13B,SEZ6,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,ATP8A1,ZSCAN30,STRADA,SEC24B,MED12L,FGR,SUCO,PCYOX1,AGAP3,PSD2,ZCCHC17,ZBED3,APOPT1,KBTBD12,B3GAT1,NRG3,DKK3,HRASLS5,ZNF44,CAB39,FAM184B,HBS1L,BRPF3,GALC,B4GALNT1,RAPGEF6,ZNF274,IP6K3,GAP43,SIGLEC8,INPP5K,ADAM28,GGTA1P,DHRS4,BRD8,TXNL4A,ZNF638,DCLK2,GPM6B,RAPGEF4,GRM7,CLASRP,IL1RAPL1,ZBTB49,BVES,IRAK3,LINC01102,HMGB1,SYNPO,OPALIN,LRRC75A,CELF5,IDH3A,GAREM2,KNDC1,TJAP1,LIX1,IL6R,TMEM240,KCND1,KCNJ3,KCNK2,KCNN3,KLC1,L1CAM,HECTD2,MAT2A,AQP11,AFF1,CD200,CCDC80,MSR1,MSRA,PTOV1,MYO7A,RTL5,HNRNPM,NCF2,VWA2,NOVA1,CLEC9A,NTRK3,NUCB2,NUMA1,SETD4,GPR88,PCDH9,PDCD2,PDE1B,GPR173,TMOD2,PFKFB4,GDAP1L1,TMIE,ZNF655,CCSER2,XRN1,PLCB2,CDIP1,RC3H2,SH3KBP1,PPM1B,CRLS1,PPP3CA,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,CNNM2,CYBC1,FAM120C,PEX2,PEX5,NWD1,RAP1GDS1,RASGRF1,ERI2,RGS3,PRIMA1,KCTD17,RNF220,CARF,GSTCD,TMEM206,PCMTD2,SNX22,NEK11,RPL15,ARMH4,SPIN3,GLDN,TCP11L1,SYNDIG1,AP1AR,MAPK12,PEAR1,SOX6,CASC3,ZNF821,GALNT10,SH3BP2,ITSN1,PPP1R9A,NTNG1,MAGI3,ANKRD6,PAAF1,ZNF365,EPN2,SLC6A1,PKNOX2,LRRC55,SLC8A2,SLC8A3,ARHGEF40,BTBD7,SLC20A2,SPHKAP,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,WDTC1,SOX3,ZCCHC24,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SMOC1,SSTR1,LARP4,ZSCAN29,SEPT8,ADHFE1,STX1A,ARHGEF9,SYN2,ANKRD28,MMS19,DDHD2,MLST8,MCF2L,FBXW11,ANO4,TBX15,ATMIN,WSCD1,SIN3B,TCF7,TCF7L2,TCF12,WDR7,NAT16,PCDHB7,AKNA,TEK,FAM200B,ZNF34,SLC44A1,FBXL16,ARL10,DAAM2,TNFRSF1B,PRRT1,PIK3R5,RGMB,NR2C2,SYNPO2,AMACR,TRPC1,DCBLD1,RUSC1,ANO5,RFTN2,TUB,CLHC1,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,SF1,KCNT2,SH3GLB2,MFF,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,NUP214,VANGL2,SSPN,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-519e*:mirSVR_highEffct hsa-miR-519e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.59E-128 8.95E-125 1.83E-127 1.69E-126 345 1503 "ABCF1,SYN3,ABHD6,KLHL32,ADCY6,ADD3,CDC7,SORCS1,PLEKHH1,PWWP2A,ADRA1D,BEND6,GPR158,SRPX,APAF1,ALS2,API5,SHTN1,PPP4R4,TMEM263,ZFYVE28,ASCL1,ASPH,CHRD,NCOA1,ATM,ATP1A2,SLC4A4,ATP1B3,ALDH7A1,DPY19L3,ADAM15,NRP2,ZNF599,CFLAR,BMPR1B,SYNJ1,ARHGEF7,CACNA1A,CACNA1B,CALB2,CALM1,PTBP2,CAST,HIP1R,SPAG9,CD38,CDC42,LGI1,L3MBTL4,CDO1,CLGN,CHM,SYNPR,COG1,ABCG2,QKI,MAP4K4,AKAP6,BTF3L4,SLC4A7,CHD1L,CREB5,NCOR1,CS,FEZ2,VAC14-AS1,PLXNA4,DZIP3,UBXN2A,PUM1,RIMS2,USP6NL,CCDC144A,NOS1AP,DOCK4,ARHGAP24,MATR3,PABPC5,ARMCX4,DNAJC6,HP1BP3,COPS7A,C2CD2L,CEP170,DDX46,RHOBTB1,SMG7,SNAP91,SACS,G3BP2,RABGAP1L,CCDC3,CHRDL1,DLG4,DMD,CPEB2,DMTF1,ABCC9,GOLT1B,EDN1,EDN3,HIPK3,SEMA3D,EFNA3,YAF2,FAM13A,PHF20L1,GOLGA7,EIF4G2,COPS4,TENM1,ELAVL2,RGS17,PAN3,LRRC17,RASGRP2,ENPP6,DENND4A,ETV1,EXTL2,ADGRV1,CLVS1,CACNG3,ACSL4,TAOK3,RACK1,CEP78,GORAB,SEC24B,FER,KIAA1109,FGF12,IP6K2,SYNCRIP,RGPD5,FOXO3,SEMA4D,ATP13A4,SGIP1,TMEM107,SPECC1,MSANTD4,NRG3,OGA,SDCBP2,MEGF11,HRASLS5,GABRB1,GABRB3,CAB39,ARPP21,DISC1,ACSS1,TUBGCP4,SULT1C4,MSTN,PPARGC1A,COPS8,HPGDS,DBF4,GLYR1,ZNF638,CBX1,MAP7D2,LUZP2,GPD2,TDRKH,GRIA1,GRIA2,GRIA4,GRIK1,NR3C1,GRM1,LINC01551,AP4S1,PSIP1,MAEL,HAS2,PTGDR2,LINC01102,MIER3,HNF4G,SMAP1,C5orf24,LRRCC1,PLD5,USP54,BRINP3,ZNF678,DIPK1A,ZNF385B,KCNA4,KCND1,KCND2,KCNJ5,KCNK2,KIF2A,KLC1,CYP27C1,CAMK2N2,HECTD2,MAOB,MBD1,KCTD6,MITF,ZNF680,ZNF92,NACA,BEX5,NCAM2,NDUFA5,NEUROD1,NF1,DNHD1,SETD4,OPA1,CLDN11,SNTG1,PAK3,PRTG,PDE1A,PDE3B,PDGFRA,CDK14,SEMA5B,PIK3R1,ZNF655,ZFYVE21,XRN1,MAPKAP1,FSD1,PPARA,MED1,CRLS1,PKN2,EPDR1,CNNM2,SLC22A23,GDPD2,PSMD13,MTMR10,PTN,TMEM260,OCIAD1,PTPRD,PTPRG,CEP97,ZNF793,SUSD4,ZNF493,RBBP6,ZDHHC14,RDX,RFX4,SEC61A2,RERGL,ALG9,RAVER2,CARF,GSTCD,NEK11,BAALC,SPIN3,ATP8B4,TCP11L1,ABCA11P,RTKN,KCNIP1,SCN8A,FNIP1,CASC3,SGK1,ITSN1,FAM102A,HKDC1,FBXO11,SLITRK3,ST3GAL3,WDR37,ZNF365,EPN2,RUFY2,SLC8A3,ARHGEF40,SIRT2,SMARCE1,RCOR3,MBD5,TMCC1,FAM126B,BDP1,KIF1B,RBM26,C11orf87,SRPK2,TAB2,POGZ,DIP2A,GANAB,AJAP1,SYNE2,VPS13A,TACR1,DDHD2,TPCN2,TRIM2,TCF12,SYNE1,PCDHB6,FAM200B,C18orf54,AP4E1,SEZ6L,TPM1,TPM3,C9orf85,RGMB,ZMYND8,TSC1,PRR18,FRRS1L,CCDC14,VSNL1,ZNF708,ZNF19,TRIM9,GPR158-AS1,ZNF154,ZNF177,INTS3,WNK1,ZXDA,CADM2,PRDM2,ADAMTS9,CIAPIN1,NAV3,PDSS2,RGS7BP,DNAH10,UBE3B,PAK5,ZNF248,DPF3" MicroRNA hsa-miR-146a*:mirSVR_highEffct hsa-miR-146a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.27E-128 1.27E-124 2.61E-127 2.40E-126 359 1625 "KCNH8,NCKAP5,NDRG3,KIDINS220,SLC24A4,HECW2,PCDH19,TAOK1,C1QTNF3,LRRC7,ALCAM,FAM135A,CDC42BPA,FGD2,USP28,PARG,APAF1,UPRT,APOC1,CACHD1,SFMBT2,TMEFF1,MARCH3,ZBTB10,DDX3Y,DCAF5,SYNJ1,NAE1,GYG2,OSGIN2,CACNA1E,THSD7A,KALRN,CANX,VXN,CBR1,KRIT1,TMEM257,CDC27,LGI1,MAGI1,TIGD7,CLGN,CFL2,SRSF11,CHM,CHN1,B4GALT6,TAOK2,RAB28,PLAA,CLU,CLTA,TJP2,QKI,LY86,NIPBL,IGLON5,CNN3,ARMC8,BTF3L4,RCHY1,CP,FAM171B,SEC31B,ANKRD44,GDA,TRIM69,LRIG1,FEZ2,ARHGEF10,OSBPL3,PDE4DIP,SLITRK5,DZIP3,UBXN2A,GREB1,NRSN1,PUM1,RIMS2,DCAF4,RUBCN,HDAC9,GPRASP1,RIPOR2,ZNF337,DGKB,DGKG,C8orf34,ZEB2,FBXL5,DDX46,GUCD1,RHOBTB1,SNAP91,DMD,RCAN1,DTNA,MAMLD1,DYRK1A,DNM1L,EDN3,EDNRB,FRY,FSD1L,YAF2,KMT5B,PLEKHA1,PAN3,EIF1,OLIG2,COQ7,SRRM1,MRPL37,CDKL3,NRN1,FCGR3A,STRADA,FDFT1,POLK,SUCO,CAP2,ATP13A4,FLT1,SLC37A3,ATP6V1H,ATP2C1,CELF1,OGA,FYB1,GABRA2,GAD1,HBS1L,AHCYL1,ZNF559,ATP8A2,CPLX2,KIAA1841,DNER,ALDH1L1,SULT1C4,MSTN,WASHC2A,NFU1,ADAM28,PCDH17,SPIN1,GNAS,GPR12,GRID1,SERP2,ATE1,GRM8,GSN,LINC01551,RASSF8,HLF,TLX1,HSF2,SHISA6,SMAP1,IRF8,FAM95B1,TJAP1,IL6ST,ZNF678,LRRTM3,ITGAM,KCNC1,KCNC2,KCNJ10,KCNK1,CREG2,KLRC2,KLC1,KTN1,STMN1,INSYN2,PAXBP1,SYTL4,HECTD2,MAP6,MAT2A,MATN2,MBNL1,MEIS2,XRRA1,STK32C,MSR1,PTOV1,MYO9A,P2RY13,NCAM1,NEUROD1,NFYA,NOVA1,NRCAM,NUCB2,OPHN1,PCSK5,PCSK2,OLA1,ABCB1,FAM218A,A2ML1,RETREG1,JAKMIP1,SCHIP1,PRRX1,POU3F2,MINDY2,PPM1B,LRRN3,PTPA,PPP2R5C,PPP2R5E,KANSL1,RANBP3L,PRKAB2,RAB39A,MAPK4,LRRC49,SIDT1,MDGA2,PTCH1,PLPPR1,TMEM260,PTPRD,PTPRG,ACSM5,RIPOR1,TMEM255A,ACSS3,SH3TC2,FAT4,RAP1GAP,ARID4A,RBBP6,SLC6A15,ZYG11B,MORC4,ARHGEF10L,SLC25A36,LGI2,YY1AP1,PCMTD2,CCDC102B,NEK11,ACER3,TCP11L1,ABCA11P,WLS,CCDC112,ATXN2,ATXN7,SCN3A,ELMOD1,SOX6,SH3GL2,DOCK10,CHD9,ST3GAL3,ZNF365,RAB3GAP1,KBTBD4,BTBD7,CPEB4,NAXD,ZFP1,OGDHL,IFT122,ANKRD36,SNRPN,UNC80,USP33,SON,SOX3,BDP1,KDM4C,ZNF423,ZC3H13,KIF1B,NPAS3,TROVE2,CLSTN2,ITPRID2,SSTR2,EPB41L3,LARP4,STAU1,ZC3H4,NUDT10,ADAMTS17,SYPL1,C12orf76,SEMA4A,DDHD2,DNMBP,ANO4,EHBP1,ACSL6,CUX2,TCF12,WDR7,SYNE1,AKNA,TNS2,FRYL,CRB1,SLC44A1,ERCC6L2,HEY2,TMPO,BEX4,RIMBP2,KCTD2,TPM3,ZNF384,SMUG1,TRIO,RUNDC3B,AMACR,PPIL6,TMEFF2,CADM1,RPL7L1,UBE2H,UBE3A,ZNF709,VLDLR,LAT2,GUSBP1,PCDH20,ZNF711,MICU3,FMN2,LYPD6,AMZ1,ZSCAN26,ZNF189,WNK1,PRDM2,STOX2,ADAMTS9,CIAPIN1,VPS35L,SNX27,CAB39L,MPPE1,WNK3,EPM2A,FAM13C,RTN4,PAK5,ADAMTSL3,RNF170,SNX14,IFT88,PRRT4" MicroRNA hsa-miR-361-3p:mirSVR_lowEffct hsa-miR-361-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.65E-128 1.49E-124 3.03E-127 2.79E-126 342 1480 "RALGAPA1,SERPINA3,CLK4,ABHD6,ADD1,ADORA2A,AP2A2,DOC2A,AMT,C6orf89,MYH7B,PPFIA4,PKP4,DGKZ,CASK,TMEFF1,SPTBN4,ASGR1,MARK4,CCDC74A,NCOA1,ATP1A3,SLC2A11,B3GALT2,RIPK1,TTLL9,ADAM15,ADGRB2,SNAI3-AS1,SYNJ2,FUBP1,JAZF1,PRMT9,GPC2,OSGIN2,RAB29,MYRF,BTRC,CA8,CACNA1D,CACNB4,DIRAS1,VXN,CAST,PRC1,METTL6,CD38,LRBA,ARHGEF2,CDC42,ADGRG1,TAOK2,LSMEM2,NRXN2,DGCR9,TMEM184B,HOMER3,CNTFR,AKAP6,SLC4A8,COX4I1,TOGARAM2,IGDCC3,CP,CHD1L,CDC42BPB,CRY2,HINFP,ANKRD44,SEC24C,CSNK1E,OSBPL3,APPL1,ECE2,CYBB,KIF26A,TBC1D5,MAML1,PHYHIP,SIRPA,ZEB2,B3GAT3,CNIH3,ZC3H11A,POM121,SV2B,SV2A,OLIG1,SLC29A4,DPP6,TOM1,USH1C,EDN1,EDNRA,EDNRB,ANKRD46,EFNA3,EIF4G1,TNK2,BSCL2,ELN,DMTN,RASGRP2,KCNMB2,DENND4A,ZNF549,PIPOX,RTN3,MRVI1,EZH1,WAC,TBC1D16,TMEM132C,DLC1,SPSB4,FGFR1,HPCAL4,SYT3,DCTN2,EFCAB2,PDLIM5,RASL10A,NPTN,GPR153,STAU2,B3GAT1,BRSK1,HRASLS5,CSDC2,GHR,KIRREL3,NTNG2,TXNL4A,COPS8,RAB30,STARD3,ZNF638,KDM2B,POLL,GPER1,NUDT21,ATP2B1-AS1,RAPGEF1,GRID1,ADAMTS8,AP4S1,LINGO1,RNFT2,TMEM179,TOX2,PADI2,MAN1B1,ARHGAP19,DDX19B,SYNPO,AGBL5,MSL1,FAM95B1,IDH3B,ZNF181,MYLK2,KIAA1755,METTL21A,KCNC1,KCNJ3,KHK,LINC00634,KIT,A1BG-AS1,SYTL4,PACRG,MAG,MAPT,SYT9,MEIS1,MEIS2,MGAT3,PPM1L,MMP16,MOBP,MOV10,MPP2,GIT1,N6AMT1,HNRNPM,NBL1,NELL2,NFIX,DNHD1,PCBP3,SMIM11A,HCN1,NTRK3,OPHN1,LOC100128398,PALM,PC,PDCD2,PDE1A,PDE2A,PDE3B,PDGFRA,NLGN3,TMIE,ANKRD16,TRHDE,PRRX1,NXPH1,POLR2F,FSD1,POU6F1,TMEM235,PPM1B,PPP3CA,KANSL1,PRKCG,MASP1,BCAS3,GDPD2,MDGA2,TMEM104,PTAFR,PTH1R,ELOVL2,PTK2,TMEM260,PTPRE,PTPRO,FAM120C,PEX2,ZSCAN2,NKAIN1,TMEM231,MARCH1,RAB5B,RAD17,ZNF793,RAP1GAP,SUSD4,RASGRF2,BSDC1,RFX4,RNF220,PBRM1,RNASEL,SETD5,YY1AP1,SNX22,EPHA10,TCP11L1,PTGR2,RYR1,SCP2,HES6,ASIC4,STUM,ASAP3,SHC4,CHD9,R3HDM2,NLGN1,PPP4R3A,BTBD3,LRRC55,SLC6A8,LGI3,ABTB1,SMARCC2,INAVA,RIMS1,SNCA,SNRPN,DOP1A,WDTC1,SOX2,KIF21B,ZSWIM8,KDM4C,TEX2,ZNF302,NKAIN2,NXT2,TTBK2,PHLDB1,SEPT3,GSE1,SUPT5H,ARC,SYN2,ASTN2,POPDC3,DDHD2,EXOC7,CAMSAP2,WWC1,VWA3A,SZT2,DOCK9,TMEM151B,AKNA,RNF216P1,CRB1,CDH22,FBXL16,THRA,NR2E1,ERCC6L2,DAAM2,FAM124A,KCTD2,R3HDM1,RBFOX2,RGMB,TRIO,AMACR,NUTM2A,FNDC5,LRTM2,HIRA,HEPACAM,NSD2,XPO1,LGI4,CFAP298,GPR158-AS1,NDRG4,PCBP1-AS1,UPF3A,SLC30A3,LRP8,XKR7,GAL3ST3,PCBP4,HRASLS,DOCK8,GJC2,CASC15,FAM219B,VANGL2,FRMD6,SPATA13,JPH3" MicroRNA hsa-miR-758:mirSVR_lowEffct hsa-miR-758:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.17E-128 1.78E-124 3.63E-127 3.34E-126 340 1464 "KCNH8,ABHD6,XKR4,KLRC4,KIAA1211,OLMALINC,MTA3,GPR158,OSBPL1A,TXNDC16,ZNF578,HFM1,LRRC7,ALCAM,OGT,DPP10,LRCH2,ANK2,APAF1,DGKZ,UPRT,LRRC4C,PPP4R4,TMEFF1,CDK13,TMEM108,EIF4G3,B3GALT2,BCHE,MIR9-3HG,KSR1,BMPR1B,LINC00906,SGCE,CACNA1G,IL33,CALB1,MAP7,PRC1,INA,REPS2,LRRFIP1,DLGAP1,RCBTB2,SOCS6,CASC2,SYNPR,RAB28,KIAA1549L,ABCG2,QKI,CNTN1,AKAP7,FAM149A,AHCTF1,BAG4,MYRIP,ANKRD44,TENM4,SEC24C,ARHGEF10,MICAL2,ATRNL1,IPCEF1,NCAN,FAM131B,KIAA0408,HDAC9,MYADM,ARHGAP24,FRMPD4,ZFYVE16,KIAA0586,KCTD8,DGKG,IP6K1,PABPC5,HEPH,MAGI2,DDX46,RHOBTB1,SGSM2,RABGAP1L,CHRDL1,DLG2,GRIN3A,DMD,CDON,DNM2,DMTF1,SLC12A6,ECM2,EBF1,EDN1,ATL1,KMT5B,ABI2,EIF4G2,EIF1,TUBD1,SPEG,KATNAL1,ZIC4,FECH,SLC9B2,MED12L,KIAA1109,FGF12,FHL1,SUCO,MEX3B,NOP56,SORBS1,PDLIM5,RASL10A,ERGIC3,SARAF,STAG2,CHL1,BRPF3,ZMYND11,SALL3,IP6K3,SYT17,ATP8A2,SRRM4,BRD8,GK,GLS,PCDH11X,FERMT2,LNX1,ADGRA3,GPD2,FUT10,GPR37,GRB10,GRIA2,C1QL4,GRIK3,GRM7,GRM8,KIF3A,RNF165,ATG4C,NXPH2,HRH3,LINC01102,BACH2,ELOVL5,AGBL5,USP51,AGFG1,MSL1,IDH3A,FAM95B1,IGF1,RBPJ,PLD5,IL6ST,KCNC2,GPR62,CREG2,KPNA5,IPO5,INSYN2,LIG4,MAN2A2,ZFYVE27,MARK3,MBNL1,SYT9,CHST6,CHIC1,LRP1B,PPM1L,MITF,MMP16,ERICH3,MSR1,CTNNA3,MTR,MYO7A,PABPC1L2A,NAP1L2,ZC3H12B,NDP,NELL2,OLR1,OPCML,GPR137C,SNTG1,PBX1,PCDH9,PCMT1,PCSK5,PDCD2,PDE4B,PDGFRA,GPR85,PFKFB4,GDAP1L1,PURG,ANKRD16,SCHIP1,SDK2,TNPO2,POU3F2,PPM1B,PPP2R5E,PPP3CB,RASGEF1B,PRKACB,PKN2,EPDR1,MAPK9,APTX,CNTLN,TMEM260,PTPRB,TMEM231,RAD52,NWD1,ZNF493,RASGRF1,ARID4A,MSANTD2,FIGN,RGS7,RGS12,RIC8B,PBRM1,RPRD1A,ZFHX4,SETD5,PCMTD2,CCDC102B,RPL15,ATP8B4,GLDN,CLIP1,SATB1,LRFN5,TNFRSF19,GALNT10,SUPT20H,MAGI3,FHOD3,ANKRD6,KDM4D,SEPHS1,ARHGEF40,SLC12A2,ELMO2,SLCO1A2,SPHKAP,RIMS1,ANKFN1,FAIM2,SNRPN,TMCC1,FAM126B,PDZRN3,SON,SOX1,MYT1L,BDP1,KDM4C,TEX2,PEG10,SPTAN1,KIF1B,RBM26,NPAS3,RAP1GAP2,DDN,SPART,LRRC4,SEPT8,KANK1,SEPT3,FAM168A,ACSBG1,SYT11,SYNE2,SYPL1,COBL,TACC1,CAMTA1,WWC1,VWA3A,ACSL6,DMXL2,CUX2,TCF7,ZEB1,TPCN2,PCDHGA11,SYNE1,PCDHB4,DICER1,ITGB3BP,AP4E1,SLC44A1,MTMR14,HEY1,TMOD1,DAAM2,TPM1,TPM3,PDSS1,STXBP4,TRPC1,TSC1,SSBP2,TTTY15,CADM1,LINC00689,UGT8,PITPNB,FLRT2,PLEKHH2,RBFOX3,P2RY12,GUSBP1,SLC47A2,MKRN3,ZFAND5,CA10,EMSY,CADM2,PRDM2,SLC38A1,FAM13C,AMN1,FZD3,RTN4,PAK5,RNF170,NETO1" MicroRNA hsa-miR-4280:mirSVR_lowEffct hsa-miR-4280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-128 1.80E-124 3.66E-127 3.37E-126 326 1348 "ACTN2,ADAR,FMNL2,KLHL32,GALNT13,BRAP,PLEKHH1,GRAMD1B,UNC5A,NLGN4X,RTL9,HACE1,ABCD2,CARNS1,UNC79,AMPD2,AMPH,LRCH2,ANK2,APBB2,APC,GPAM,PHYHD1,VAT1L,TNRC6C,API5,USP37,AQP4,SEMA4G,PRX,ZNF582,BID,CFLAR,PROM1,CDK5R1,SCAPER,WASF1,IL33,CACNA1D,CACNA1E,DDR1,CALB1,KALRN,CANX,VXN,VSTM2A,ISPD,MTMR7,CDC27,CDH2,CCPG1,SRSF11,CASC2,NDST3,KMT2C,CPNE6,CLTB,QKI,AKAP5,ZNF521,ZFP28,HS3ST5,CP,C2CD2,CREM,GDA,TRIM69,CSF1R,ARHGEF10,SUSD5,VCAN,NCAN,PDE4DIP,PITPNM3,CTH,EARS2,DGKB,PABPC5,ARMCX4,ELMSAN1,ZBTB24,KIAA0319,MAGI2,ARNT2,DLG3,RAB39B,TRAPPC9,CASP8AP2,SLC25A18,ARRDC4,ECM2,DNAJB6,EBF1,EDNRB,PHF20L1,ABI2,KCTD3,EIF5,TNK2,RGS17,DCTN4,VPS13B,RCAN2,RABEPK,CEP85L,SPEG,ETV1,RCSD1,FAM198B,RPS6KC1,TOMM40L,FCGRT,GORAB,FGFR1,FHL1,MEX3B,CAP2,EFCAB2,JKAMP,CAMKK2,ATP6V1H,ATP2C1,ST6GALNAC3,NSG1,STAU2,MSANTD4,NRG3,MPP6,MEGF11,GAB1,GABRA1,CHL1,GABRB1,HBS1L,SIGLEC8,ZNF559,SULT1C4,MSTN,CYP46A1,GGT7,PPARGC1A,TCERG1,FERMT2,WDFY3-AS2,GPR12,GPR37,PCLO,DIDO1,GRIA4,GRM7,TMEM25,KAT7,ADAMTS6,WIF1,ZDHHC15,TCEAL6,IDH3A,C2orf72,IGFBP1,DOCK7,PLD5,LIX1,ZNF678,SLC35G1,OLFM3,KCNQ3,KIF2A,KLRC2,KTN1,LAMP2,VWA5A,HECTD2,MBD1,MIA2,MITF,ZNF680,ADAM22,MSR1,ZNF92,CTNNA3,RSPO2,RTL5,NAP1L2,NELL2,NRCAM,NTRK2,DDR2,IGSF11,OMG,OPCML,OPHN1,PAK3,DPY19L2P2,ETFRF1,PCMT1,PCSK1,PCSK5,PIK3C2A,ZFYVE21,PLCL1,PCDH18,PNMA3,RC3H2,ING3,SEPT4,EPB41L4B,SLC36A4,FAT3,PPARA,PPM1B,PRKAB2,PKIA,EPDR1,MAPK7,VPS13C,SNRK,WDR25,PTCH1,UHRF1BP1,PTPRD,PTPRE,CASTOR1,NKAIN1,ZNF844,ZNF493,OXR1,RBBP6,RDX,REV3L,ERI2,ALG9,CCDC102B,SPIN3,ATP8B4,MEG3,ABCA11P,HSD11B1L,WLS,RXRG,RYR3,TRAPPC13,AP1AR,SATB1,FNIP1,SUPT20H,PPM1E,CPEB3,FBXO11,FNDC3A,R3HDM2,CNKSR2,SEC31A,ZNF365,KANSL3,SLCO1A2,TET1,ZFP1,MBD5,SNRPN,USP33,DOP1A,PDZD2,MYT1L,SOX5,SP4,NMNAT2,C11orf87,CLASP2,TROVE2,SS18,FCHO1,NECAB1,FGD4,VPS13A,SYPL1,TAC1,ATP11A,SEMA4A,TMEM136,ANO4,DMXL2,SATB2,TPCN2,DOCK9,TMEM151B,USP32P1,ATP13A2,ITGB3BP,HHIP,AKTIP,ERCC6L2,SEZ6L,WBP2,SYNPO2,TRO,STXBP4,LRTM2,TMEFF2,SLAIN1,PITPNB,OSBP2,USP1,P2RY12,NSD2,ZNF708,MICU3,LYPD6,TCEAL7,ZNF138,ZBTB38,ZBTB16,ZNF195,PLPPR5,WNK1,LRP8,SLC38A1,XKR7,ADAMTS9,SIGLEC10,KCNAB1,PARP11,PHTF2,RNF170,NETO2,NETO1,CPNE4" MicroRNA hsa-miR-4272:mirSVR_highEffct hsa-miR-4272:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.55E-128 1.99E-124 4.04E-127 3.72E-126 323 1324 "SYS1,ACTN2,KDM5D,CCDC85A,GALNT13,BRAP,SLC12A5,ADORA3,AP2A2,WDR35,CC2D2A,SMIM17,LRCH2,USP28,APC,GPAM,ALS2,SHTN1,PPP4R4,TMEM263,ARNTL,CDK13,MARK4,ASPH,ZSCAN18,RASL11B,DDX3Y,ATP2A2,ATP2B3,RNF182,ATP6V0A1,BACH1,JAZF1,CACNA1G,WASF1,CACNA1A,THSD7A,ZNF501,LDB2,KRIT1,USP6,CBFA2T2,DGKI,CDH8,CCPG1,CFL2,ADGRG1,SOCS6,CASC2,LHX2,PLAA,CLCN3,NMT2,QKI,NIPBL,AKAP7,ARMC8,FAM149A,AKAP5,RCHY1,MFSD4A,PNKD,GDA,PHF14,PNPLA8,EDRF1,DOCK4,ZFYVE16,CENPL,LONRF1,ARMCX2,C8orf34,ZEB2,BLOC1S6,POM121,RHOBTB1,SPOCK3,RABGAP1L,WDR20,SEC16A,DLG2,CPEB2,RCAN1,DYRK1A,EDN3,SYT15,SEMA3D,TMTC1,FAM13A,PLEKHA1,ELAVL4,CALCRL,EN2,TMEM74,CDKL3,ETV1,WAC,FABP7,RPS6KC1,PTK2B,ATP8A1,CEP78,ZSCAN30,MED12L,FGF13,FGF14,BAIAP2,FHL1,POLK,SUCO,ANKFY1,SGIP1,SLC37A3,FOLH1,C2orf88,SORBS1,UFM1,PDLIM5,CELF1,STAU2,ZMAT1,GABRA1,CHL1,ZMYND11,SIGLEC8,C15orf41,CPLX1,DNER,ARFIP1,MALT1,RNPS1,PCDH11X,KDM2B,GPD2,TDRKH,RAPGEF4,ATP2B1-AS1,GRIA2,GRIA4,GRIK2,PRDM5,ZNF496,GUCY1B1,WIF1,MAEL,RASSF8,HPS5,FRMD3,HLF,CFAP126,NEGR1,FAAP20,IDH3A,ZIC5,RBPJ,IGSF1,LIX1,TUBB2B,ZNF385B,KCNC2,KCND2,KCNN2,KTN1,LAMP2,NCOA7,PACRG,EFHB,SRSF12,KITLG,MITF,AFDN,XRRA1,CD200,COL28A1,MSR1,NRBP2,CTNNA3,NCAM1,NEK1,NELL2,NFE2L2,CNOT4,SLC11A2,NRCAM,TBC1D25,OLR1,CLDN11,PRTG,PDE4B,PIRT,SLC10A4,CDK14,SNX10,PLP1,PCDH18,PURG,STRN3,PSAT1,SEPT4,NXPH1,PPARA,PPM1B,TATDN3,PPP2R2C,PPP2R5E,PPP3CB,PKIA,EPDR1,GRAMD1C,MDGA2,CNTLN,MTMR10,OCIAD1,PTPRE,PTPRO,PPP2R3C,RAD17,RALGDS,FAT4,ZNF493,OXR1,RASGRF2,RBBP6,GAL3ST4,REV3L,GTDC1,SLC25A36,C12orf49,RPL15,TCP11L1,LRRK2,CLIP1,ZNF354C,LRFN5,ELMOD1,DOCK10,MAGI3,FNDC3A,FHOD3,BTBD3,SLC8A3,SLC14A1,ATF7IP,TET1,CPEB4,SORCS3,LIMCH1,KIF13A,UNC80,USP33,TRERF1,SP4,SPP1,ZBTB43,LMO3,SRPK2,PBLD,TROVE2,LRRC4,TTBK2,GSE1,KLHL7,SYT11,SYNE2,ADAMTS17,PLCB1,SYT4,MTCL1,DDHD2,TAF9,ADGRL3,KLHL4,KIAA0930,TPCN2,RPGRIP1L,WASHC4,PCDHGA11,SYNE1,DOCK9,PCDHB3,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,TEK,AP4E1,THRA,TLR4,NR2E1,TMOD1,TP53BP1,C9orf85,RGMB,ANKRD20A2,UBE3A,SLAIN1,VLDLR,ZFP37,ZBTB14,ZIC1,ZNF24,MICU3,ZNF70,FMN2,SMARCAD1,EMSY,CADM2,PRTFDC1,SCG2,HPS4,SLC17A6,RGS7BP,FZD3,HNRNPA3,PHTF2,CASC15,RNF170,SOCS4" MicroRNA hsa-miR-181d:PITA hsa-miR-181d:PITA_TOP PITA 3.96E-128 2.23E-124 4.50E-127 4.14E-126 255 816 "CPNE2,KCNH8,SLC25A25,FMNL2,TMEM132B,SLITRK1,CCDC85A,SLC12A5,ERMN,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,ANK1,API5,CDC14B,SEMA4G,MADD,CAPRIN2,DDX3Y,SLC4A4,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,ADGRB3,DCAF5,JAZF1,WASF1,FOXK1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,SYNPR,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,TENM4,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,TOX,LONRF1,CTIF,ELMSAN1,MFAP3L,BLOC1S6,ZC3H11A,POM121,SPOCK3,G3BP2,MTX3,WDR20,ARNT2,NR1D2,CDON,DPP6,DPYSL2,ABI1,PDCD6IP,E2F5,ST8SIA3,KLHL5,FSD1L,MBNL2,EGR3,ELAVL2,PAN3,EN2,EPS8,NCALD,CLVS1,ZIC4,DLC1,ATP8A1,MEX3B,PCYOX1,SYT3,NPTN,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GPR22,CECR2,RAPGEF4,GRB10,GRIA2,GRIK2,NR3C1,GRM5,CIT,ADAMTS6,WIF1,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,DOCK7,KCNC2,KCNMA1,IPO5,LIFR,LMO1,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,RSPO2,HS6ST3,NEXMIF,ZC3H12B,NEFH,OTOGL,CNOT4,NOVA1,HCN1,IGSF11,GPR88,GPR137C,KCNK10,PCSK1,PRTG,PDE3B,PDGFRA,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,FAT3,POU3F2,PPARA,PPP2R5E,CEP41,PROX1,CNNM2,PTPRE,FAM120C,USP47,FIGN,RFX2,PRIMA1,TTLL7,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,ATXN1,FNIP1,SOX6,SCG5,ITSN1,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,PALLD,TMCC1,FAM126B,DOP1A,SOX5,NMNAT2,RBM26,LMO3,SRPK2,CAMTA2,EPB41L3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,GSE1,PRRC2C,MTCL1,UNC5D,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,PSD3,SLC35G2,SIRT1,THBS4,HEY2,TNS1,NR2C2,PITPNB,SF1,ZIC2,ZIC3,ZNF28,SMARCAD1,WNK1,SEMA3B,PAK5,PHTF2,SOCS4,SLC4A10" MicroRNA hsa-miR-181b:PITA hsa-miR-181b:PITA_TOP PITA 3.96E-128 2.23E-124 4.50E-127 4.14E-126 255 816 "CPNE2,KCNH8,SLC25A25,FMNL2,TMEM132B,SLITRK1,CCDC85A,SLC12A5,ERMN,UNC5A,HECW2,PCDH19,OSBPL8,FAM135A,OGT,CDC42BPA,DPP10,ANK1,API5,CDC14B,SEMA4G,MADD,CAPRIN2,DDX3Y,SLC4A4,ATP2B1,ATP2B2,RNF182,MTMR9,NOL4,ADGRB3,DCAF5,JAZF1,WASF1,FOXK1,CALB1,CALM1,KALRN,PTBP2,CAMK2G,LRBA,DCLK1,DLGAP2,CACNA2D2,SYNPR,KMT2C,KIAA1549L,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP7,AKAP6,AKAP5,ABI3BP,TBPL1,BAG4,IGDCC3,SLC35F1,GDA,TENM4,SEC24C,OSBPL3,CSNK1G3,ATRNL1,CNTNAP2,PLCXD3,PUM1,USP6NL,DOCK4,GAPVD1,TOX,LONRF1,CTIF,ELMSAN1,MFAP3L,BLOC1S6,ZC3H11A,POM121,SPOCK3,G3BP2,MTX3,WDR20,ARNT2,NR1D2,CDON,DPP6,DPYSL2,ABI1,PDCD6IP,E2F5,ST8SIA3,KLHL5,FSD1L,MBNL2,EGR3,ELAVL2,PAN3,EN2,EPS8,NCALD,CLVS1,ZIC4,DLC1,ATP8A1,MEX3B,PCYOX1,SYT3,NPTN,FUT9,MEGF11,GATM,GCNT2,TTBK1,TCERG1,SPIN1,GPD2,GPR22,CECR2,RAPGEF4,GRB10,GRIA2,GRIK2,NR3C1,GRM5,CIT,ADAMTS6,WIF1,BACH2,MIER3,HLF,NEGR1,AGFG1,HSF2,SOWAHA,ZIC5,DOCK7,KCNC2,KCNMA1,IPO5,LIFR,LMO1,MAPT,MARK1,MAT2A,MBNL1,ADAM11,CHIC1,AFF1,MSI1,RSPO2,HS6ST3,NEXMIF,ZC3H12B,NEFH,OTOGL,CNOT4,NOVA1,HCN1,IGSF11,GPR88,GPR137C,KCNK10,PCSK1,PRTG,PDE3B,PDGFRA,PDPK1,GNG2,PIK3C2A,CCSER2,LRP12,SCHIP1,EPB41L4B,FAT3,POU3F2,PPARA,PPP2R5E,CEP41,PROX1,CNNM2,PTPRE,FAM120C,USP47,FIGN,RFX2,PRIMA1,TTLL7,PBRM1,ZFHX4,ALG9,ROBO2,CLIP1,RYR3,ATXN1,FNIP1,SOX6,SCG5,ITSN1,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,EPN2,PKNOX2,CPEB4,SNAP25,PALLD,TMCC1,FAM126B,DOP1A,SOX5,NMNAT2,RBM26,LMO3,SRPK2,CAMTA2,EPB41L3,LARP4,NKAIN2,SEPT8,KANK1,SEPT3,GSE1,PRRC2C,MTCL1,UNC5D,TBL1X,SIN3B,DMXL2,TRIM2,CLASP1,SYNE1,PSD3,SLC35G2,SIRT1,THBS4,HEY2,TNS1,NR2C2,PITPNB,SF1,ZIC2,ZIC3,ZNF28,SMARCAD1,WNK1,SEMA3B,PAK5,PHTF2,SOCS4,SLC4A10" MicroRNA hsa-miR-583:mirSVR_highEffct hsa-miR-583:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.31E-128 3.55E-124 7.15E-127 6.58E-126 337 1442 "SDE2,KCNH8,TKTL1,KDM5D,ARID1A,KLHL32,ADCY6,SORCS1,GRAMD1B,ADRA1D,ADRB2,DPY19L2P4,KLHL13,OSBPL6,CC2D2A,CEP126,AMPH,OGT,ANK2,USP28,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,FAM131A,MIER1,MARCH3,DACT3,ZBTB10,RASL11B,CCAR2,ATP1B3,N4BP2L1,NOL4,NRP2,BLM,KSR1,SYNJ2,NAE1,CACNA1B,CACNB2,THSD7A,TRIM41,SLC25A14,MAP7,NFS1,CERS5,MTMR7,SEPT7,CDC42,TIGD7,RCBTB2,TAOK2,LHX2,EPS15L1,CLCN3,FBXO7,QKI,CNGA3,IQCK,PCYT1B,SLC25A27,ABI3BP,BAG4,ENTPD4,ANKRD44,SNCAIP,CSF2RA,SEC24C,MICAL2,OSBPL3,NCAN,PDE4DIP,PHACTR3,SLITRK5,PHF14,NRSN1,RIMS2,DCAF4,USP6NL,NOS1AP,CYBB,DOCK4,KATNAL2,ZFYVE16,EARS2,ZNF337,DGKB,DBN1,YTHDC1,ELMSAN1,ZEB2,CEP170,FBXO25,SMG7,SGSM2,G3BP2,FAM107B,DLG2,DNM1,DNAH9,NR1D2,DRD1,DSCAM,DTNA,DYRK1A,ABCC5,EBF1,FAM135B,EDN3,SYT15,FSD1L,EFNA3,EIF5,ING4,C8orf37,CALCRL,PAN3,EIF1,EN2,EPB41L2,RCAN2,KCNMB2,IGSF6,CDHR1,PIPOX,SIRPB1,EXTL2,F8,FAM198B,WAC,PTK2B,ZIC4,FDFT1,ZNF589,GORAB,FGFR1,FHL1,CAP2,IP6K2,FLT1,C2orf88,NBEA,SORBS1,SPECC1,FAM49B,ERGIC3,DACH2,B3GAT1,NRG3,ZNF512,FYB1,FYN,FAM120B,GALC,ZNF234,GAP43,SIGLEC8,C15orf41,DISC1,ADAM28,MMADHC,MALT1,BRD8,GK,GLDC,KDM2B,EML4,CNTRL,RAPGEF4,GRIA4,GRM7,KAT7,MFSD2A,PSIP1,GABARAPL2,CPT1C,HSPA1L,FAAP20,IRF8,MSL1,IGF1,IL6R,IL6ST,INPP1,DIPK1A,NME9,JAK1,KCND2,KIF5A,KIT,LIMS1,SYTL4,VWA5A,HECTD2,NCOA7,MAOB,LYPLAL1,MAT2A,MBNL1,TM6SF1,LRP1B,MEST,MMP16,MN1,MOG,ERICH3,TAGLN3,MXI1,RCOR2,NF1,CNOT4,NOVA2,P2RY1,CNTN3,PCDH9,PDE1C,PDGFRA,CDK14,SERPINE2,PIK3R1,ST8SIA5,PLP1,PCDH18,PURG,RC3H2,PSAT1,LRRN3,PPP2R5C,PPP2R5E,CEP41,PRPSAP2,VPS13C,MDGA2,CNTLN,PTK2,ZSCAN32,PTPRD,NWD1,OXR1,RASGRF1,ARID4A,UBR7,MRPS18A,SEC61A2,EXD2,PRR5L,ABCA11P,KCNIP1,ZNF568,RYR3,S100B,AMER2,LRFN5,LRRTM4,SCN7A,TRIM46,FOXRED1,ASRGL1,KIF27,SH3GL3,KIF16B,NTNG1,SHMT2,CNKSR2,NLGN1,ST3GAL3,ANKRD6,PAAF1,PPP4R3A,KANSL3,SLC11A1,KBTBD4,SLC12A2,NAPB,ATF7IP,CPEB4,SMARCE1,INAVA,SON,TRERF1,TNIK,BDP1,DOK5,KDM3A,UHRF1BP1L,KIF1B,SRPK2,CLSTN2,ITPRID2,STOX1,ERBIN,RGL1,GSE1,KLHL7,VAMP1,SYT4,FAM208A,CUX2,TCF7L2,TRIM2,RPGRIP1L,PCDHGA4,OBSL1,ARHGAP9,PCDHA5,FRYL,TEX15,CRB1,ZMAT3,ZNF34,TIAM1,ERCC6L2,TRPS1,DCBLD1,TSN,SSBP2,TTC3,CADM1,UBE3A,MGAT5B,BEST1,XRCC4,ZFP37,ELFN1,UPF3A,CA10,NAV3,SLC17A7,WNK3,MVB12B,RGS7BP,DNAH10,PAK5,KAT6A,JMJD1C,CBLN2,SLC4A10" MicroRNA hsa-miR-4318:mirSVR_lowEffct hsa-miR-4318:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-127 6.03E-124 1.21E-126 1.12E-125 362 1659 "VWA5B2,ASIC2,GALNT16,ADCY2,ADCY6,ADD1,ADD2,ADD3,BRAP,MTA3,ZNF608,KCTD16,NME5,TXNDC16,ALCAM,BCAR3,CARNS1,GPRASP2,ZNF687,AMPD2,C6orf89,MYH7B,PKP4,CNTNAP1,DDO,TMEFF1,DACT3,TMEM108,CCDC181,ATP1B3,ALDH7A1,NOL4,BARD1,BCL2L2,NRP2,CFLAR,BMPR1B,SYNJ2,KALRN,HAP1,PTBP2,SYT6,SPAG9,CBS,CCNH,USP2,CD86,REPS2,CDH8,ZMYM4,EVI5L,LGI1,CCPG1,CLGN,COPB2,DLGAP3,CLTA,DNAJB5,QKI,MAP4K4,TMEM155,BTF3L4,SLC4A8,SMARCAL1,ZFP28,RBM39,AKAP12,CSNK1E,OSBPL3,ATRNL1,VCAN,CST3,RASGEF1C,KIAA0040,PLCXD3,CTNND2,NOS1AP,KIAA0408,BOC,TOX,LONRF1,KIAA0586,SPOCK2,AIF1L,DCT,HP1BP3,MAGI2,LYPD1,SV2B,SV2A,RABGAP1L,WDR20,KBTBD11,GRIN3A,DMD,USP3,DYNC1I1,DNM2,DOCK2,DPH1,DRP2,DSCAM,ARRDC4,DYRK1A,ABCC5,DNM1L,SEZ6L2,FAM135B,FCF1,SEMA3D,EBI3,GOLGA7,ASB3,ELAVL4,DCTN4,EN2,ENO2,EPB41L1,EPB41L2,COQ7,SEZ6,RABEPK,CEP85L,MRPL10,RASL12,SIRPB1,FAM198B,ZIC4,TAOK3,CORO2B,DLC1,KIAA1109,BAIAP2,POLK,PCYOX1,SYNCRIP,SLC37A3,NOP56,SORBS1,ARFGAP2,MEGF10,GAB1,HRASLS5,ZMYND11,RAPGEF6,ARPP21,NEU3,MSTN,AHDC1,ADAM28,PCDH17,MALT1,SPIN1,RAB30,POLL,LUZP2,LOXL3,PRRC2B,GPD2,TDRKH,RAPGEF4,GRB10,GRIA4,PLCD4,PSIP1,ADAMTS6,MAP4K5,TMEM179,IRAK3,NXPH2,MAN1B1,HMGB1,IGF1,IGFBP1,IL6ST,KCNA6,KCNK2,KCNMA1,KIF5C,LMO2,SYTL4,C2orf80,GPR155,MARK1,MATN2,CHIC1,POC1B,MKLN1,ERICH3,SCG3,LYRM9,NEXMIF,NAP1L2,ZC3H12B,NELL1,NF1,NOVA1,NPTX1,NUCB2,OCRL,GPR88,CHAMP1,OGG1,OLR1,PCSK5,PCSK2,CDK18,PDE4B,NLGN3,ZFYVE21,PLIN1,LRP12,PSAT1,EXOSC10,ING3,FAT3,MINDY2,CRLS1,KANSL1,SLC26A11,GRAMD1C,SYTL2,SPDL1,PTPRG,FAM120C,C1orf109,PEX2,RAB3IL1,PID1,USP47,SUSD4,ARID4A,MSANTD2,RDX,ZYG11B,RFX5,ZDHHC4,RGS7,PRIMA1,ARHGEF10L,SLC25A36,SETD5,PCMTD2,NEK11,FBXW7,ZC3H14,ZNF331,TMEM156,FOXRED2,CSRNP3,SUPT20H,TRA2B,FERMT1,DOCK10,FNDC3A,FHOD3,R3HDM2,SYBU,NLGN1,ZNF365,RPH3A,PPP4R3A,KDM4D,SLC8A3,ARHGEF40,CCDC88A,TRIM67,SHANK2,ANKRD36,SNRPN,SOX2,NMNAT2,HECW1,MYCBP2,RBM26,LRRC4,SS18,CEP68,KANK1,FAM168A,MLC1,SYT4,TAC1,TACC1,TACR1,KAZN,TAF9,DNMBP,TAL1,KLHL4,ATMIN,DMXL2,TCF12,WDR7,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,HIF3A,DICER1,SIRT1,ZFPM2,ITGB3BP,ZMAT3,TMEM9,DDHD1,TLR4,TMPO,DAAM2,RIMBP2,RBFOX2,TPD52,ZNF384,RGMB,ZNF346,SYNPO2,METTL3,SMUG1,TRIO,RUNDC3B,ZMYND8,RUSC1,TTC3,TMEFF2,TUBB1,FAM155A,UBE2H,SLC35A4,OSBP2,PLEKHH2,BCL2L13,RICTOR,GUSBP1,XPO1,XRCC4,ZNF24,TRIM9,LYPD6,SPHK2,CELF4,ZBTB16,AMZ1,DPYSL5,PLPPR5,DHX33,CA10,EMSY,SLC38A1,CSDE1,NAV3,NAV2,FIP1L1,PLSCR4,RGS7BP,RTN4,KAT6A,HNRNPA3" MicroRNA hsa-miR-708*:mirSVR_lowEffct hsa-miR-708*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-127 7.22E-124 1.45E-126 1.34E-125 330 1387 "SYN3,ASIC1,ABHD6,ACTN2,CSMD3,ESYT2,SLC24A4,INTS2,TBC1D14,WDR35,TXNDC16,HFM1,C1QTNF3,SMIM17,CEP126,MARCH4,AMPD3,BIN1,USP28,PHF12,ANXA7,EPB41L5,MAGEE2,CACHD1,API5,PPP4R4,ARHGAP5,DACT3,ZBTB10,NCOA1,NUMB,DDX3Y,ATM,ATP2A2,ATP2B2,NOL4,ATP6V1G2,DNAJC27-AS1,BMPR1B,CACNA1G,C5,WASF1,IL33,CACNA1D,CACNB2,CACNB4,CALB1,THSD7A,CALM1,PTBP2,ISPD,RUNX1T1,USP6,FOXN3,TJP2,QKI,TMEM155,PCYT1B,ARMC8,AKAP6,ABI3BP,CLOCK,C2CD2,CREM,CREB5,AKAP12,GDA,RGS6,IPCEF1,VCAN,CNTNAP2,DZIP3,PITPNM3,APPL1,PUM1,EDRF1,BOC,HDAC9,ARHGAP32,TM9SF4,MATR3,DNAL1,DBN1,SPATA2,YTHDC1,DNAJC6,ZEB2,MYEF2,MAGI2,KLHL3,ALKBH8,POM121,PLPPR4,SACS,FAM107B,CCDC3,ARNT2,DLG2,DMD,HS3ST4,NR1D2,DMTF1,CASP8AP2,DNM1L,ABCC9,E2F5,EDN1,EIF4G2,EIF5,TENM1,BSCL2,STARD3NL,VPS13B,SEZ6,NCALD,EXTL2,SH3YL1,ACSL4,ATP8A1,ST3GAL6,FKTN,STRADA,TESK2,GORAB,FECH,FGF1,POLK,CAP2,SYNCRIP,SLC37A3,ARFGAP2,ERGIC3,CELF1,MSANTD4,TBR1,ABLIM2,GABRG1,FAM120B,JPH4,ERAP1,DNER,TUBGCP4,HEPN1,TCERG1,COPS8,GLUL,ZNF638,LNX1,LPAR4,TMEM121B,RAPGEF4,GRB10,ZNF496,RNF165,SOX21,MAP4K5,HLF,NEGR1,AGFG1,SMAP1,IL6R,ITGA7,ITPKB,KCNA6,KCNJ10,KCNMA1,KIF2A,KIF5A,KIF5C,LAMA2,LAMP2,STMN1,LIMS1,GPR155,ZFYVE27,CHST6,MID1,PPM1L,SAMD5,MTTP,MYO5A,MYO9A,MYT1,ZC3H12B,NDP,SFR1,NEK1,NFE2L2,NODAL,NTRK2,OPCML,PDE3B,SLC10A4,OLA1,CDK14,SERPINE2,XRN1,FAM216A,PLCL1,PMP2,PPARA,PPM1B,PPP3CC,PRKCB,DIRAS2,WBP1L,SNRK,CNTLN,OCIAD1,PTPRG,ZNF615,TUG1,RAD51D,FAT4,RASGRF2,RADX,ZDHHC14,SLC6A15,RET,RGS4,SEC61A2,SLC25A36,LGI2,GSTCD,PCMTD2,NEK11,ARMH4,MCMBP,ATAT1,SAFB,CSRNP3,LRRTM4,SCP2,SOX6,GALNT10,COPZ1,ITSN1,SH3GL2,DOCK10,ST3GAL3,ZNF365,BTBD3,SMTN,SLC14A1,BTBD7,ATF7IP,CPEB4,ARFGAP1,CDK5RAP2,SMARCD3,ANKRD36,MBD5,ZNF415,SNRPN,FAM126B,SCN3B,PDZD2,MYT1L,TRERF1,TNIK,ZCCHC24,BDP1,FNBP1,KDM3A,EMC1,ERC1,CDK19,C11orf87,CLSTN2,SEPT8,KLHL7,FGD4,COBL,TACR1,CAMSAP2,FAM208A,ADGRL3,SMG6,DMXL2,TCF7,CLASP1,SYNE1,RALYL,PCDHB9,PCDHAC2,PCDHA7,CRTC1,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,ITGB3BP,AP4E1,HHIP,ARL10,TIAM1,TIE1,HEY1,TMPO,RIMBP2,TPD52,TPM3,NR2C2,PDSS1,TRPS1,HEPACAM,FAM155A,PLEKHH2,BCL2L13,GUSBP1,XPO1,FMN2,LYPD6,REEP1,ZFAND5,PMEPA1,EVI5,ADAMTS9,NAV2,FIP1L1,RGS7BP,ST7,KAT6A,SNX14,SLC39A12,FXR1,SLC4A10" MicroRNA hsa-miR-3137:mirSVR_lowEffct hsa-miR-3137:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.32E-127 7.43E-124 1.49E-126 1.37E-125 333 1412 "KDM5D,GPRIN1,SLC12A5,SORCS1,ADORA3,ZNF608,GPR158,RTL9,TXNDC16,CC2D2A,C1QTNF3,ALCAM,ARHGAP20,PCDH10,UNC79,OGT,ANK3,FGD2,PPFIA1,CNTNAP1,DGKD,FAM131A,CACHD1,TNRC6C,API5,AQP4,AQP6,CDK10,ARSF,CDK13,PDE8B,MARK4,NCOA1,TMEM108,N4BP2L1,BACH1,ADGRB3,BCHE,DCAF5,ST3GAL5,SCAPER,MTMR3,NIPA1,BTRC,CACNA1D,KALRN,PTBP2,CAMK2G,LDB2,TMEM257,CD38,ASIC3,CHRM1,SYNPR,EPS15L1,RAB28,NMT2,FADS2,ABCG2,CNN3,IQCK,PCYT1B,ARMC8,COL9A2,IFFO1,COX4I1,TCEAL2,MFSD4A,CLOCK,RNF14,CS,SNCAIP,FEZ1,CSNK1G3,VAC14-AS1,KIAA0040,MYADM,HDAC4,EARS2,ZNF337,DAPK1,PITPNC1,YTHDC1,ELMSAN1,HEPH,COPS7A,MAGI2,SRGAP3,RABGAP1L,PDCD6IP,DNAJB6,ABCC9,E2F5,E2F6,YAF2,PHF20L1,KMT5B,RASA4,EIF4G2,EIF5,TENM1,VPS13B,COQ7,DMTN,EFS,SPEG,ETV1,DNAJC27,RASL12,EXTL1,NRN1,F3,ARMCX1,FABP7,PTK2B,SCML2,MED12L,KIAA1109,FGFR1,AMOTL2,POLK,VTI1B,NELFCD,TMEM175,SORBS1,HVCN1,TRIM16,CELF1,AP4B1,PHYHIPL,MEGF11,GABRA3,BRPF3,NCKAP1,IQGAP2,ACSS1,AHDC1,GHR,ZNF276,TCERG1,DBF4,GLRB,TOX3,PCDH11X,RAB40B,GPR17,NUDT21,RAPGEF4,C1QL4,NR3C1,CLASRP,COQ10A,AP4S1,PSIP1,MAEL,MIER3,HPSE2,HMGCR,ZDHHC15,NEGR1,AGFG1,DHX35,HTR5A,KNDC1,INPP5B,ZNF385B,KCNB1,KCNH1,KCNJ3,KCNJ16,KCNK1,LAMP2,STMN1,LMO2,MBD1,MDM4,MEST,MMP16,MSRA,NRBP2,MTTP,RSPO2,MYO9A,RTL5,ZNF862,NAP1L1,NDUFA5,SLC11A2,NRCAM,NTRK2,NTRK3,ODF2,OPCML,OPHN1,LOC100128398,OPRL1,P2RX7,SNTG1,CNTN3,PDCD2,PDE1A,PDE4D,ENPP2,PFKFB2,OLA1,NALCN,C11orf49,STRN3,PRRX1,MAGEL2,SPATA6,SEPT4,FAT3,FSD1,PPM1B,KANSL1,PKN2,MAPK10,GDPD1,CNNM2,SLC22A23,CYBC1,MDGA2,QRICH1,PSMD13,UHRF1BP1,TMEM260,PTPRG,FAM120C,PTPRZ1,TUG1,PLEKHB2,FAM66C,RASGRF2,ARID4A,SLC6A15,DPF2,RFX2,RFX4,PRIMA1,TTLL7,RIT2,SLC25A36,RIC8B,ZNF532,CYB561D1,RPL15,FBXW7,BAALC,ZC3H14,ACER3,RXRA,FOXRED2,SALL1,SATB1,SCN3A,LRRTM4,FAM19A1,GALNT10,TRA2B,SCAF8,SGK1,ZFP30,ITSN1,CPEB3,NTNG1,SHC4,FNDC3A,ST3GAL3,BTBD3,WDR47,RUFY2,LRRC55,SLC6A7,SEPHS1,ARHGEF40,ELMO2,SLIT1,INAVA,SON,WDTC1,SOX5,ZSWIM8,SP4,EMC1,TSPYL2,C11orf87,SEPT8,STAC2,FGD4,JMJD6,SYN2,POPDC3,TBL1X,NAT16,TMEM151B,SIRT1,ITGB3BP,HHIP,TMPO,RIMBP2,PIK3R5,SEZ6L,TPM1,TPM3,NR2C2,TRO,CLHC1,HIRA,TUBB1,UGT8,OSBP2,CCDC14,KCNT2,CA10,SLC30A4,PRDM2,PRTFDC1,TMEM163,TRIM16L,WIPF2,RGS7BP,FZD3,DOCK8,PAK5,CASC15,ACTR3B,ADAMTSL3,ADAMTS10,ZDHHC20,SOCS4,FAM198A,JPH3" MicroRNA hsa-miR-9-5p:TargetScan hsa-miR-9-5p TargetScan 1.52E-127 8.51E-124 1.70E-126 1.57E-125 280 997 "ABAT,ASIC1,ACTN2,FAM43B,ARID1A,ADARB2,GALNT16,ADCY5,ADCY6,ADD2,RNF150,ESYT2,PTCHD1,NLGN4X,HECW2,AK2,ALAD,ALCAM,PCDH10,GPRASP2,PITPNM2,ANK2,PKP4,PARG,GPAM,KIAA1614,ARHGDIA,CDK13,DACT3,CCAR2,DDX3Y,INSYN2B,HCN2,KSR1,DST,MTMR2,MYRF,CACNA1E,CACNB2,CALB2,PTBP2,MAP7,RUNX1T1,CCNT1,CBFA2T2,LRBA,ARHGEF2,EVI5L,L3MBTL4,DLGAP2,GPR37L1,FOXN3,KIAA1549L,CLCN4,NMT2,FAM19A5,QKI,HECTD1,FHL5,CNTFR,COL9A1,BAG4,NSL1,CLOCK,C2CD2,CREB5,HAPLN1,NCOR2,AATK,MICAL2,OSBPL3,PLXNA4,FAM169A,PITPNM3,GREB1,RIMS2,CCDC144A,ARHGAP24,FRMPD4,PHF19,RIMS3,DGKB,DCC,PITPNC1,ARMCX2,DCTN1,JAKMIP2,MFAP3L,RHOBTB1,SACS,FAM107B,CPEB2,ABI1,DRP2,PDCD6IP,DYRK1A,EBF1,FAM135B,HIPK3,CNNM1,FRY,FSD1L,OPTN,PHF20L1,EGR3,EIF5,ELAVL2,PLEKHA1,ELAVL4,EN2,RCAN2,KCNMB2,ENPP6,EFEMP1,ATP8A1,CHST15,FGF12,FGF14,AMOTL2,FOXG1,FOXO3,DCTN2,C2orf88,CAMKK2,GPR153,DOT1L,GABRB1,ILDR2,GAD1,BRPF3,B4GALNT1,ARPP21,MTHFD2,AHDC1,GFAP,PCDH17,C1QL1,LYVE1,KIAA1958,GPR26,CECR2,GRIK3,PTPRT,IL1RAPL1,GUCY1A2,ATOH8,HAS2,KLF12,MIER3,ACOT7,AGFG1,HSP90AA1,ICA1,IGF1,C5orf24,IL6R,IL6ST,KCNA1,KCNB1,KCNK3,KCNN3,KCNQ3,CREG2,KIF5C,LIFR,NCOA7,MBNL1,ADAM11,LDLRAD3,MEF2C,KITLG,AFF1,MMP16,DBNL,MDGA1,MYO9A,NAP1L1,NEK1,NFIA,NME4,NPTX1,OPCML,GPR137C,KCNK10,PAK3,CNTN3,PCDH9,PCSK5,PCSK2,CDK18,PDE3A,PDE3B,PIRT,BEST3,PIK3C2A,CCSER2,PRRX1,PACSIN1,PPARA,MAPK4,CNNM2,MDGA2,PIGG,PTCH1,EML5,PTPRG,MARCH1,RAB3IL1,RAB5B,RALGDS,RASGRF2,PRRT2,RFX3,PBRM1,ALG9,RORB,MCMBP,RPS6KA2,HUNK,RXRA,AMER2,FOXRED2,ATXN1,SCN2B,FNIP1,COPZ1,KIF21A,ARX,CPEB3,NTNG1,AMBRA1,FAM81A,RPH3A,CCDC88A,BTBD7,ATF7IP,CPEB4,OGDHL,MBD5,KIF13A,CMTR2,FAM126B,NFASC,COLGALT2,ELOVL4,PHLDB1,ATP11A,ANKRD12,DDHD2,FAM208A,KIAA0930,DOCK9,PSD3,FRYL,DICER1,AP4E1,FBXL16,GZF1,CBX5,ASXL3,NR2E1,KCTD2,RBFOX2,RASD2,DOK6,RUNDC3B,EVI5,PRDM10,ADAMTS9,ITM2C,GOPC,FAM13C,PHTF2,CERS6,RSPRY1,NHSL1,FXR1,FRMD6,DPF3,RNF146" MicroRNA hsa-miR-4277:mirSVR_highEffct hsa-miR-4277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.58E-127 8.89E-124 1.78E-126 1.64E-125 326 1355 "ACADM,ARID1A,ADD3,ERMN,KIAA1211,HECW2,OSBPL6,ALAD,SMIM17,ABCD2,ARHGAP20,PCDH10,CDC42BPA,DPP10,CCDC146,MAP4K3,PHF12,PARG,GPAM,DDO,LGR5,AQP6,SEMA4G,TMEFF1,ASPH,ATP2A2,B3GALT2,ADAM23,ADGRB3,BCL7A,MTMR2,JAZF1,CALB1,THSD7A,KALRN,CH25H,RUNX1T1,KRIT1,CD86,ARHGEF2,ZMYM4,CDH18,TIGD7,CASC2,DLGAP3,CPNE6,NRXN3,COG1,CLTC,NGEF,FAM189A2,FHL5,CNTN1,LETMD1,SLC4A7,ABI3BP,CHD1L,AKAP12,RNF14,ANKRD44,GDA,SOCS5,PDE4DIP,FAM169A,NRSN1,GAPVD1,RIPOR2,DCAF8,CENPL,PABPC5,ELMSAN1,MYEF2,TIAM2,MAGI2,GSDME,DDX46,SACS,RABGAP1L,RAB39B,DNM1,SLC29A4,CDON,DMTF1,DPYSL2,ABI1,DTNA,KRBA2,E2F5,EBF1,WDPCP,EDNRA,SH3GLB1,CELSR3,PHF20L1,KMT5B,AASS,ASB3,EPB41L1,EPHB1,GPHN,SRRM1,CEP85L,ZNF549,TLR7,EXTL2,KATNAL1,F5,WAC,ACSL4,FCGR1A,FER,MED12L,SUCO,MEX3B,FOXG1,CAP2,SGIP1,SORBS1,UFM1,CGREF1,AP4B1,ZNF512,STAG2,GABRA2,GAD1,ZMYND11,NCKAP1,MTHFD2,DISC1,GART,DNER,IGSF5,GHR,PPARGC1A,TOX3,ADGRA3,GPD2,PRUNE2,GPR17,GPR37,CNTRL,STMN2,DIDO1,GRIA4,GRID1,NR3C1,GRM7,FAM19A2,GSTM5,IRAK3,TOX2,ZHX1,NXPH2,HNMT,HNRNPK,HSF2,HSPA1L,HTR5A,PLD5,IL6ST,INSM1,LRRTM3,NME9,KCNC2,KCND2,KCNK1,KCNMA1,KIF2A,LAMP2,STMN1,FGFBP3,ASPRV1,SMAD1,TM6SF1,LRP1B,MEIS1,MIA2,PPM1L,AFDN,ADAM22,MYCN,FXYD6,P2RY13,NCAM1,NDUFA5,CNOT4,NOVA1,NRCAM,NTRK2,NUCB2,PDE3B,PDYN,GNG2,PLCL1,JAKMIP1,EXOSC10,SCHIP1,ING3,EPB41L4B,DRAM2,MED1,PTPA,RANBP3L,PRKAB2,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,OCIAD1,PTPRD,PTPRG,PEX5,STRC,SUSD4,ARID4A,DBX2,ERI2,GTDC1,RFX4,RGS7,KLHL11,SEC61A2,RIC8B,RNASEL,RPRD1A,ZFHX4,CARF,ROBO2,RORB,RPE,RPL15,FBXW7,BAALC,NCBP3,ATXN7,SCN2A,ELMOD1,IL17RB,SEC14L1,ITSN1,FNDC3A,SEC31A,NUBPL,ABLIM3,SLC6A1,ARHGEF40,CCDC88A,ELMO2,SLC22A4,CXXC4,SMARCE1,SNCA,KIF13A,SON,KDM3A,ENKUR,GLT8D1,HECW1,ZC3H13,CDK19,SPART,ATP10B,SSTR1,SULF2,ACSBG1,PRRC2C,SYNE2,SYT1,COBL,SYT4,SEMA4A,DDHD2,UNC5D,ATMIN,ACSL6,DMXL2,ZEB1,SZT2,SYNE1,RALYL,TEX15,LEFTY2,SLC44A1,TIAM1,HEY1,TLR4,NR2E1,CSMD1,TP53BP2,ZNF346,TRIO,STXBP4,NTSR2,DCBLD1,TTPA,CLHC1,RPL7L1,UBE3A,UGT8,SLAIN1,BCL2L13,VLDLR,TBC1D15,P2RY12,WRN,XRCC4,ZNF24,CELF4,REEP1,FSTL5,SMARCAD1,EMSY,STOX2,HPS4,PCDH15,KCNAB1,TMEM163,PARP11,FZD3,SMIM8,PHTF2,MSRB3,SSPN,SLC4A10,FAM198A" MicroRNA hsa-miR-155*:mirSVR_lowEffct hsa-miR-155*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.77E-127 9.96E-124 1.98E-126 1.83E-125 335 1430 "ACADM,ASIC1,CLK4,FAM43B,CSMD3,NDRG3,ADAR,TMCC3,USP31,PWWP2A,SNX30,BEND6,NLGN4X,MTUS1,KCTD16,TBC1D14,KIAA1324,TAOK1,LRRC7,GOLGA7B,ZFAT,CCDC146,SUGT1P4-STRA6LP-CCDC180,PKP4,KCNAB2,APBB2,DGKD,AMER3,TNRC6C,USP37,LGR5,CDC14B,SPTBN4,ARNTL,STK33,RIPK1,TTLL9,SEC11C,FGF17,LINC00906,LDLRAD4,CFAP410,CACNA1D,KALRN,ISPD,METTL6,AIFM1,CDC25B,CDH2,ZNF445,FOXN3,RAB3C,CLCN4,NRXN1,TMEM155,AHCTF1,SEC31B,C2CD2,CREM,RBM39,HAPLN1,TENM4,CSF2RA,MICAL2,PDE4DIP,PHACTR3,APPL1,PUM1,ST18,NOS1AP,KIAA0408,DOCK4,ARHGAP32,ZFYVE16,TM9SF4,AIF1L,GIT2,DNAL1,MYEF2,CEP170,GUCD1,SMG7,SV2B,SPOCK3,SRGAP3,KBTBD11,NR1D2,SLC12A6,DPP6,DRP2,ARRDC4,DYRK1A,DNM1L,SEMA3D,TMTC1,KCTD3,EIF4G2,C3orf18,EPHA5,STX2,ZNF549,MRPL37,F5,SCML2,ZNF589,FECH,FER,FGF12,POLK,MEX3B,IQCG,C2orf88,ZBED3,ATP2C1,STAU2,OGA,ZMAT1,GABRA1,HRASLS5,GABRB1,GABRB3,CAB39,GAD1,GALC,RAPGEF6,ARPP21,ERAP1,IGSF5,SRCAP,GFER,PCDH17,PPARGC1A,GLS,TNRC6A,PCDH11X,CBX1,GNAS,WDFY3-AS2,GPD2,GPR37,CECR2,GRB10,DIDO1,GRM3,GRM7,LINC01089,RNF165,ZBTB49,LINC01551,MAP4K5,NXPH2,FRMD5,ARHGAP19,KLF12,MIER3,AGBL5,HNMT,ZNF491,SHISA6,ICA1,IDH3B,LINC00667,RBPJ,DOCK7,CLVS2,KCNMA1,GATD1,LIFR,SYTL4,MAN2A2,MAP2,MAP6,MATN3,MBP,SYT9,KITLG,SCAMP5,MOBP,ADAM22,MYH6,MYO6,MYO9A,SLCO1C1,NFIA,NFE2L2,NOVA1,SLC11A2,NUCB2,OPHN1,P2RY1,ZDHHC22,PAH,PDE4D,PDGFRA,ZNF655,GPSM2,ING3,CRLS1,RASGEF1B,CEP41,PRKCB,MAPK4,PTCH1,SPDL1,PTN,ZSCAN32,OCIAD1,FAM120C,PTPRZ1,TTC13,TUG1,CEP97,SLC25A48,SH3TC2,ZNF493,MSANTD2,SLC6A15,RFX5,RGS3,RNASEL,RPRD1A,ARMC5,PCMTD2,ACER3,TCP11L1,MEG3,KCNIP2,STX1B,DGLUCY,SBF1,CSRNP3,ATXN1,LINC00461,TRA2B,ZFP30,PPP1R9A,SH3GL3,PPM1E,CPEB3,HKDC1,MAGI3,FBXO11,FNDC3A,NUBPL,PAAF1,WDR37,ABLIM3,ZNF365,BTBD3,LRRC55,SLC8A3,SLC12A2,ZFP1,SMARCA4,SMARCE1,RCOR3,SNRPN,TMCC1,PDZD2,BDP1,FNBP1,SOX11,KDM3A,KIF1B,CDK19,ATP10B,INKA2,ELOVL4,SEPT8,RGL1,STX1A,GSE1,SYT1,COBL,TACR1,ANKRD12,MTCL1,FAM208A,UNC5D,CNTN2,IQCE,TBL1X,EHBP1,DMXL2,SATB2,CUX2,TCF12,WDR7,AZIN2,NAT16,ARHGEF12,USP32P1,CRTC1,DICER1-AS1,LEFTY2,AP4E1,FBXL16,ARL10,TIAM1,TJP1,HEY2,TMPO,BEX4,PRRT1,CSMD1,TP53BP2,TRIO,RUNDC3B,TRPS1,TMPRSS5,CA14,CLHC1,HEPACAM,FLRT2,BCL2L13,MTCH1,VLDLR,NSD2,GUSBP1,ZIC3,ZNF24,SPIRE1,ZFAND5,SYNC,PRDM2,LMAN2L,FAM47E,HRASLS,SMIM8,FBXO36,ADAMTSL3,TRAM2-AS1,NETO1,SLC4A10,ZNF30" MicroRNA hsa-miR-455-5p:mirSVR_lowEffct hsa-miR-455-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.91E-127 1.07E-123 2.14E-126 1.97E-125 334 1422 "RALGAPA1,ABCF1,ARID1A,FMNL2,ADARB2,ADCY2,PSMG3-AS1,GALNT13,RNF157,UNC5A,KIAA1211,ESYT2,NME5,WDR35,TXNDC16,CC2D2A,SEMA6A,MARCH4,PITPNM2,PHF12,ANXA7,DGKD,CACHD1,LGR5,AQP4,SEMA4G,PDXK,IGDCC4,LINC00173,STK33,MARK4,CAPRIN2,ATM,ATP2B3,ADAM15,SNAI3-AS1,LINC00847,BBS2,MPDZ,BCL2L2,KSR1,BMP7,SYNJ1,SYNJ2,ARHGEF7,JAZF1,RAB29,MMD2,KALRN,PTBP2,CAMK2A,SLC25A14,NFS1,CLDN10,CERS5,MTMR7,TMEM257,L3MBTL4,LOC730101,CCPG1,CHGA,CHM,CLCN4,NMT2,IGLON5,IQCK,ARMC8,AKAP6,ABI3BP,ACBD5,ZNF521,AKAP12,HINFP,GDA,TENM4,RGS6,SUSD5,ATRNL1,VCAN,PDE4DIP,CST3,SLITRK5,CTH,CTNND1,NRSN1,RIMS2,KIAA0408,BOC,HDAC9,DGKB,TOMM20,SCRN1,ARMCX4,SPATA2,YTHDC1,ZEB2,MFAP3L,TMEM130,SPOCK3,CCDC3,KBTBD11,HS3ST2,ACOT8,DYRK1A,ABCC9,EDN1,EDNRB,ATL1,SGK2,HIPK3,FSD1L,SH3GLB1,EGFR,EML1,STARD3NL,DMTN,EPHA5,EPHB1,GPHN,SPEG,F3,REEP2,F8,TMEM132C,FKTN,SPSB4,FGFR1,FHL1,POLK,SUCO,SCARA3,FLNC,PSD2,TMEM107,APOPT1,NRG3,TVP23A,GABRA2,CAB39,ZMYND11,INPP5K,WASF3,LRRC37A6P,MSTN,ADAM28,GGT7,LYVE1,CRCP,GLS,TOX3,PCDH11X,MAP7D2,CNDP1,NUDT21,BTN2A1,LINC00839,LINC01551,RNFT2,GUCY1B1,TOX2,ATXN2L,VSIG4,IRF8,C5orf24,IGFBP1,LRRC25,DOCK7,BRINP3,INPP5B,ZNF385B,ITPKB,KCNA4,KCND2,KCNN3,GATD1,CYP27C1,LMO1,NCOA7,GPR155,MAT2A,MBNL1,SYT9,MDM4,LRP1B,MEST,MN1,DBNL,N6AMT1,LYRM9,MYO6,NEXMIF,ZNF862,NAP1L2,NTRK3,GPR88,OPCML,OPHN1,LOC100128398,PALM,PDE4D,GNG2,SERPINI1,CAMKV,KCTD15,LRP12,POU3F2,PPARA,PPP2R5C,PPP2R5E,KANSL1,MAPK10,NDUFS7,PTHLH,STK32A,PTPRE,PID1,USP47,SH3TC2,SUSD4,GAL3ST4,SLC6A15,ZMAT4,TRIM68,TTLL7,RNF220,PBRM1,CARF,ROBO2,BAALC,STK32B,SYNDIG1,NCBP3,HOGA1,ASIC4,GALNT10,SH3GL3,FERMT1,DOCK10,FUZ,R3HDM2,SLITRK3,NLGN1,ST8SIA1,DZIP1,NUBPL,ABLIM3,SLA,ZNF365,SLC1A3,URGCP,WDR47,SLC6A1,SLC6A8,SLC6A9,KDM4D,SEPHS1,SLC8A1,ARHGEF40,SLC22A4,CPEB4,COA1,RCOR3,KIF13A,SON,SOX2,KIF21B,SOX11,ENKUR,HECW1,IDI2-AS1,SPTAN1,KIF1B,NPAS3,NFASC,LHPP,TAB2,TROVE2,ZC4H2,NKAIN2,NEK4,RGL1,FGD4,SYN2,COBL,TACR1,EXOC7,ADGRL3,TMEM136,ANO4,ACSL6,SIN3B,TPCN2,TRIM2,RPGRIP1L,AZIN2,SYNE1,PCDHB9,USP32P1,SIK3,TEK,ATP13A2,ZFPM2,TGFBR3,MTMR14,PARD3,TPM1,C9orf85,ZNF346,TRPS1,TUB,CADM1,RPL7L1,UGT8,SLAIN1,PORCN,ZBTB14,ZIC1,ZNF711,KCNT2,PLPP4,SLC26A10,MKRN3,ZBTB16,SYNC,EMSY,STMN4,FAM47E,PDSS2,FBXO36,ADAMTSL3,JMJD1C,RNF170,SOCS4,SLC4A10" MicroRNA hsa-miR-4320:mirSVR_lowEffct hsa-miR-4320:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.13E-127 1.20E-123 2.38E-126 2.19E-125 329 1381 "NBAT1,SYS1,ADAR,ADCY2,ADD3,PTCHD1,MTUS1,KIAA1324,OSBPL8,CEP126,PCDH10,SYT13,APC,GPAM,PPFIA3,SHTN1,SHROOM2,AQP4,MIER1,DACT3,NCOA1,ALDH4A1,ATP2B3,N4BP2L1,BBS2,LINC00906,CASTOR3,CACNA1G,CACNA1A,CACNA1B,CACNB2,CACNB4,CAMK2G,BRSK2,PRC1,LDB2,DCLK1,CDH18,LOC730101,LARGE1,DLGAP1,SRSF11,CHM,ZBED5,EPS15L1,RAB33A,CLCN4,NRXN1,COL4A5,AKAP5,ABI3BP,RBM39,CRY2,SNCAIP,RGS6,FEZ2,CSNK1E,SUSD5,PLXNA4,PITPNM3,PPP1R16B,APPL1,UBXN2A,PNPLA8,NOS1AP,CYBB,BOC,DOCK4,GAPVD1,RIPOR2,DCAF8,ZNF337,MATR3,IP6K1,SIRPA,HEPH,B3GAT3,TIAM2,FBXL5,SMG7,SGSM2,G3BP2,ARNT2,KBTBD11,USP3,DOCK2,RCAN1,DTNA,ECM2,DYRK1A,EDN1,SEMA3D,KMT5B,IRAK4,PLEKHA1,TMEM35A,USPL1,EMX2,EN2,EPHA5,ENPP6,SRRM1,NCALD,RTN3,DNAJC27,RCSD1,ADGRV1,EZH1,REEP2,F8,FER,SUCO,SEC23B,RGPD5,SLC37A3,EFCAB2,TRMO,NBEA,HVCN1,DACH2,B3GAT1,SARAF,AP4B1,NRG3,STAG2,GABBR1,GABRG2,DISC1,WASF3,LRRC37A6P,SRCAP,COPS8,GLS,PCDH11X,STARD3,KIAA1958,MAP7D2,WDFY3-AS2,TDRKH,GPR12,STON1,EML4,GRIK2,ATE1,PRDM5,KIF3A,PSIP1,ADAMTS6,ATOH8,MUM1,PADI2,ZHX1,VSIG4,ELOVL5,FAAP20,FAM95B1,RBPJ,IL6ST,ZNF385B,SLC35G1,KCNN1,KIF5A,SYTL4,HECTD2,PIK3AP1,ADAM11,EFHB,MEF2C,MID1,MITF,BLOC1S2,NRBP2,TAGLN3,CTNNA3,MYH6,RTL5,ZNF862,SLCO1C1,NNAT,NPTX1,NRCAM,NUMA1,OLR1,PAK3,ETFRF1,PDE3B,PDE4D,CYTL1,NLGN3,NALCN,TMIE,CCSER2,TMEM38A,NLE1,PLCB2,FTO,EXOSC10,ING3,POU3F2,MED1,PPP1R1A,MAPK4,GRAMD1C,RELN,UHRF1BP1,BDNF-AS,PTPRB,PTPRD,FAM120C,ZSCAN2,CEP97,TMEM255A,SLC25A48,FAM184A,FEZF2,ZDHHC14,BSDC1,RDX,GTDC1,RFX3,RGS7,LGI2,KLHDC8A,ALG9,GSTCD,ROBO2,KIAA0895L,STK32B,LGR4,HUNK,ATAT1,KCNIP3,FAM192A,CSRNP3,LRFN5,SCN3A,PEAR1,ASRGL1,ITSN1,KIF16B,CPEB3,MAGI3,ST3GAL3,DZIP1,KDM4D,RAB3GAP1,SLC11A1,SLC12A2,SLC15A2,TMEM132D,ELMO2,BTBD7,COA1,SNAP25,MBD5,KIF13A,ZNF415,SNRPN,FAM219A,TSNAXIP1,SOX10,ERC1,PEG10,ZNF423,ARHGAP26,TSPYL2,CLASP2,CAMTA2,COLGALT2,ITPRID2,STOX1,NKAIN2,NCDN,ZSCAN29,ADAMTS17,SYN1,COBL,SYT4,KAZN,ADGRL3,TMEM136,TBX15,DMXL2,CLASP1,PCDHB3,TEX15,TLL2,R3HDM1,TPM3,TPM4,DOK6,METTL3,RUNDC3B,STXBP4,ANO5,RFTN2,ZKSCAN5,HIRA,HEPACAM,SLAIN1,OSBP2,USP1,VAV2,NSD2,WNT7A,XRCC4,ZBTB14,ZNF28,CFAP52,FMN2,CELF4,POLR3H,FSTL5,EVI5,PCDH15,URM1,NAV2,SLC17A7,SNX27,WNK3,SLC17A6,MVB12B,KAT6A,CERS6,ACTR3B,RNF170,MSRB3,SOCS4,LAS1L" MicroRNA hsa-miR-1267:mirSVR_lowEffct hsa-miR-1267:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-127 1.42E-123 2.81E-126 2.59E-125 359 1637 "SERPINA3,ABAT,ARID1A,CSMD3,TMEM132B,GALNT13,ADORA3,BEND6,AP1B1,PCDH19,OSBPL1A,KIAA1324,OSBPL6,AK2,C1QTNF1,SPARCL1,SMIM17,ALCAM,SRPX,PCDH10,FAM135A,SUGT1P4-STRA6LP-CCDC180,USP37,LGR5,ARNTL,DDX3Y,TMEM108,SLC2A11,N4BP2L1,DOCK11,ADAM23,NRP2,CACNB2,KALRN,CAMK2D,TRIM41,CAST,MAP7,LRBA,CDH2,DCLK1,IGFN1,NRXN3,TJP2,FAM19A5,C4orf33,AKAP7,IQCK,ARMC8,RTTN,BAG4,MYRIP,ZFP28,HAPLN1,GDA,CLIP3,CS,CSF1R,MICAL2,ATRNL1,SIPA1L1,PDE4DIP,RASGEF1C,FAM169A,PNPLA8,CTNND1,NRSN1,RIMS2,DOCK4,GAPVD1,HDAC4,ZNF337,TBC1D5,MATR3,DGKG,TMEM170A,TOMM20,BRINP1,DBI,DNAL1,PITPNC1,ARMCX2,YTHDC1,DNAJC6,MFAP3L,DDX46,RHOBTB1,G3BP2,CHRDL1,DMD,OLIG1,DMTF1,SLC12A6,CASP8AP2,DPP6,DTNA,DNAJB6,DYRK1A,DNM1L,GOLT1B,FAM135B,EDNRB,ATL1,SGK2,SEMA3D,FRY,YAF2,EFNB3,MBNL2,TNK2,RGS17,EPB41,LRRC17,RASGRP2,SEZ6,EPHA5,GPHN,EPS8,VPS26C,TLR7,MRVI1,EZH1,CLVS1,WAC,RPS6KC1,CACNG2,TAOK3,ATP8A1,TESK2,ZNF589,SEC24B,FGF11,FGF13,POLK,CAP2,IP6K2,SYNCRIP,JKAMP,PDLIM5,TPK1,ST6GALNAC3,SARAF,PHYHIPL,FAM120B,ZMYND11,SALL3,ZNF274,NCKAP1,ZNF559,ATP8A2,INPP5K,WASF3,TUBGCP4,ARFIP1,CYP46A1,GFRA2,GHR,LYVE1,CRCP,RAB30,PCDH11X,LUZP2,FUT10,LILRA1,GPER1,NUDT21,STMN2,TPPP,RAPGEF1,GRID1,GRIK1,GRIK2,GRM7,CIT,TMEM25,KAT7,GUCY1A1,IRAK3,MAEL,RASSF8,HAS2,FRMD3,SYNPO,HTR5A,ICA1,LIX1,KCNC1,KCNC2,KCNK2,KIF5C,MAP2,LYPLAL1,LRP1B,MEIS2,MID1,XRRA1,MRPL42,SCG3,CTNNA3,MYO5A,MYO9A,RCOR2,CCDC13,NEUROD1,ALDH1L2,CNOT4,NOVA1,NRCAM,HCN1,NUCB2,TBC1D25,PAX6,PDE4D,PDGFRA,GPR85,PFKFB3,OLA1,CDK14,GDAP1L1,SEMA5B,PIK3CD,ZNF655,SNX10,PLCL1,PLXNB3,PNMA3,LRP12,SCHIP1,FAT3,PPP2R2B,PPP2R5C,PPP2R5E,PPP3CC,PRKAB2,MAPK4,HYDIN,RELN,WBP1L,SIDT1,DEF8,PIGG,OCIAD1,PTPRD,PTPRZ1,PEX2,TTC13,CEP97,SLC25A48,ATG16L1,FAT4,NWD1,RBBP6,ZYG11B,DPF2,GTDC1,FIGN,PRIMA1,SEC61A2,CCDC82,RAVER2,NEK11,UEVLD,ZNF331,SATB1,ATXN7,LRFN5,SCN3A,SCN8A,GALNT10,SUPT20H,SCG5,FNDC3A,DZIP1,ANKRD6,ABLIM3,ZNF365,URGCP,LRRC55,SLC6A8,SLC11A1,SLC14A1,SLCO1A2,CPEB4,NAXD,GKAP1,LIMCH1,SNAP25,MBD5,MYO16,KDM4B,DOP1A,SOX5,GLT8D1,NFASC,ATP10B,SS18,CEP68,RGL1,ADHFE1,SEPT3,GSE1,SYN2,TACC1,FBXW11,ANO4,VWC2,DMXL2,ZFP90,TCF7,TCF12,USP22,DOCK9,TMEM151B,RALYL,OBSL1,GPRIN3,TEX15,FAM200B,DICER1,ZFPM2,ITGB3BP,AP4E1,FBXL16,FAM124A,NPL,TPM2,ANKRD20A2,TMEFF2,RPL7L1,UBE3A,FRRS1L,CCDC136,ZNF781,CLDND1,RICTOR,GUSBP1,SLC13A3,ZBTB14,ZNF711,ZNF708,ZNF28,TRIM9,SPIRE1,SLC30A4,CADM2,SIGLEC10,PCDH15,KCNAB1,SLC17A6,EPM2A,GOPC,FZD3,PAK5,CAMK1G,NUP214,MSRB3,NHSL1,SLC39A12,SENP7" MicroRNA hsa-miR-216b:mirSVR_highEffct hsa-miR-216b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.53E-127 1.42E-123 2.81E-126 2.59E-125 336 1440 "CLK4,NCKAP5,SYS1,CSMD2,CSMD3,KLHL32,SLITRK1,BRAP,PLEKHH1,PTCHD1,NR0B1,ZNF578,HFM1,TAOK1,C1QTNF3,SPOP,ZFAT,LRCH2,MAP4K3,USP28,PKP4,APBB2,ALS2,DDO,APP,MIER1,ZFYVE28,CADPS,BRINP2,NUMB,ASTN1,ATP1A2,RNF182,ALDH7A1,N4BP2L1,SEC11C,NRP2,BMP7,DST,NAE1,CA8,CACNA1E,CACNB2,KALRN,VXN,CAST,RUNX1T1,INA,C1orf52,LRRFIP1,CLGN,CFL2,CHM,CASC2,B4GALT6,NDST3,KMT2C,DNAJB5,C4orf33,QKI,NIPBL,AKAP6,COL4A5,BTF3L4,SLC4A8,TCEAL2,ACBD5,CPS1,FAM171B,CRY2,CLIP3,MROH8,LRIG1,ARHGEF10,SIPA1L1,PDE4DIP,DZIP3,RIMS2,FAM131B,CCDC144A,DOCK4,HDAC4,MATR3,MAML1,TMEM170A,PABPC5,ARMCX4,C8orf34,MYEF2,FBXL5,BLOC1S6,DDX46,WDR20,EXOG,HS3ST2,CPEB2,PDCD6IP,DNM1L,EBF1,EDIL3,EDNRA,EDNRB,HIPK3,CNNM1,MBNL2,PLEKHA1,ELAVL3,PCOLCE2,CALCRL,EN2,EPHA5,CEP85L,ZNF549,CDHR1,CLVS1,FAM198B,ACSL4,FCGR1A,CHST15,ZSCAN30,FDFT1,FER,KIAA1109,POLK,SUCO,CAP2,FOXM1,ATP13A4,SPECC1,APOPT1,TVP23A,GABRA2,GABRA3,GABRB1,CAB39,GAD1,ZMYND11,TMEM8B,ATP8A2,ALDH1L1,GCNT2,ARFIP1,WASHC2A,GLRB,GPD2,GPM6A,GPR19,PCLO,DIDO1,GRIK2,GRM5,PSIP1,GUCY1A2,WIF1,MAEL,DDX19B,HLF,HMGCR,TCEAL6,ZNF546,ZIC5,IL6R,JAK2,OLFM3,KCNC1,KCNMA1,CREG2,KIF5C,LAMP2,INSYN2,LIMS1,ARHGAP12,SMAD1,MBD1,MDM4,MEF2C,CD200,MRPL42,SAMD5,BCO1,MSR1,ZNF92,CTNNA3,MYO7A,NF1,NFIX,NOVA1,NUCB2,IGSF11,OPHN1,CNTN3,PDE3A,PDE4D,FAM218A,FAM216A,FTO,PCDH18,HMGCLL1,PMP2,CDIP1,EXOSC10,SCHIP1,SPATA6,FAT3,PPARA,PPM1B,CRLS1,PPP2R5C,PPP3CB,PRKACB,EPDR1,MAPK9,RELN,GON4L,CNTLN,ANKHD1,PTPRB,PTPRN2,PTPRO,PEX5,USP47,NWD1,OXR1,RASGRF2,RBBP6,BSDC1,RDX,RFX3,RFX4,RFX5,UBR7,SLC25A36,SETD5,CARF,ROBO2,CCDC25,RPE,RPE65,TCP11L1,NCBP3,ZNF331,CCDC112,SAFB,MIR124-2HG,TNFRSF19,CASC3,SCAF8,SGK1,FRMPD1,FBXO11,FNDC3A,CTXN2,SLC1A3,PPP4R3A,LRRC55,SLC6A11,SLC8A3,ARHGEF40,SLC14A1,SPHKAP,SORCS3,ANKRD36,MBD5,TMCC1,SOX1,SOX5,KIF21B,TEX2,ZNF423,ZC3H13,SPART,C11orf87,SMOC1,EPB41L3,LARP4,ZSCAN29,FGD4,VPS13A,PLCB1,SYN2,TACC1,MTCL1,DDHD2,ANO4,VWA3A,TCF7L2,ZEB1,RPGRIP1L,PCDHGA11,SYNE1,PCDHB7,TEX15,C18orf54,ITGB3BP,HHIP,GALNT17,ARL10,TK2,ASXL3,DDHD1,TLR4,TMPO,CSMD1,NPL,TPM3,PRMT8,AMACR,PPIL6,TSN,TTTY15,LRTM2,USP1,VAV2,TOM1L2,CCDC14,WIPF1,CFAP298,PCDH20,KCNT2,TRIM9,ZSCAN26,ZNF189,EMSY,PRDM2,STOX2,ADAMTS9,FIP1L1,PLSCR4,PARP11,C12orf4,PDSS2,AMN1,KAT6A,PHTF2,JMJD1C,SLC4A10" MicroRNA hsa-miR-29a:mirSVR_lowEffct hsa-miR-29a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-127 1.80E-123 3.55E-126 3.27E-125 356 1612 "VWA5B2,ABCF1,ACADM,CLK4,SYS1,NDRG2,FMNL2,SLITRK1,SORCS1,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,LRRC7,SEMA6A,CARNS1,AMPD3,ZFAT,CDC42BPA,LRCH2,ANK3,FGD2,CCDC146,KCNAB2,DGKZ,UPRT,DGKD,PHYHD1,TNRC6C,USP37,SHROOM2,CDK10,ARHGAP5,ARHGDIG,ARSF,MARK4,ZBTB10,DDX3Y,ATM,ATP2B3,DOCK11,ADAM15,DCAF5,SYNJ2,MTMR2,JAZF1,LDLRAD4,CA4,CACNA1A,CACNA1E,KALRN,CAMK2G,CANX,BRSK2,RUNX1T1,ARHGEF25,TMEM257,C1orf52,CD81,CDC42,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,CASC2,SYNPR,B4GALT6,CHRNB2,CNOT8,EPS15L1,NMT2,CLTC,QKI,SULT4A1,NIPBL,WHRN,BTF3L4,AKAP5,IFFO1,MFSD4A,CP,NCOR2,ARHGEF10,CSNK1E,ATRNL1,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,CTNND1,NRSN1,DCAF4,NOS1AP,CYBB,HDAC9,ARHGAP32,KATNAL2,RIPOR2,HDAC4,TOMM20,IP6K1,BRINP1,SIRPA,ARMCX4,ELMSAN1,DDX46,ALKBH8,PLPPR4,DLG2,CDON,FAM57B,DPYSL2,ABI1,ARRDC4,ECM2,WDPCP,SGK2,SEMA3D,SIDT2,EFNB3,LPAR6,GOLGA7,KCTD3,PLEKHA1,C8orf37,MTSS1L,SEZ6,ENPP6,ERCC2,NCALD,SPEG,MRPL37,TLR7,CLVS1,WAC,POLR1B,FGFR1,HPCAL4,IP6K2,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,ZCCHC17,SMC2,TRIM16,STAU2,KBTBD12,MSANTD4,ABLIM2,GAP43,ERAP1,TUBGCP4,SRCAP,PCDH17,PPARGC1A,DBF4,GLI2,PCDH11X,STARD3,POLL,GNAS,WDFY3-AS2,GP1BB,DIPK1C,PRLHR,CECR2,GRIA2,C1QL4,GRIA4,GRIK2,ADAMTS13,NR3C1,RNF165,WIF1,MUM1,RASSF8,ARHGAP19,TNFAIP8L3,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,DISP2,TUBB2B,ZNF385B,KCNC2,TTYH2,LAMP2,STMN1,LIFR,VWA5A,MAT2A,AQP11,SCAMP5,MKLN1,MOG,COL28A1,COMMD5,MYO9A,RTL5,FXYD6,NEFM,NFIA,NFE2L2,NFIX,NPPA,HCN1,OXTR,P2RY1,KCNK10,PALM,PAX6,CDK18,PFKP,PIK3R1,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,RETREG2,WBP1L,SIDT1,PIGG,UHRF1BP1,EML5,FAM120C,PEX5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RDX,ZYG11B,TRIM68,RET,ERI2,GTDC1,ZFHX4,SETD5,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,EMID1,PAQR6,ABCA11P,KCNIP2,HOGA1,SMPD3,GALNT10,FOXRED1,KIF21A,PPM1E,DOCK10,ZNF365,RPH3A,PKNOX2,SLC6A8,SEPHS1,LGI3,SORCS3,TTC17,RIMS1,MAPKBP1,MBD5,SNRPN,SCN3B,DOP1A,SON,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,C11orf87,ZNF302,ERBIN,CEP68,ADHFE1,STX1A,NSFL1C,ZC3H4,SUPT5H,SYNE2,ADAMTS17,SYN2,COBL,C12orf76,ATP11A,TACC1,CAMSAP2,VWA3A,SIN3B,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZFP91,DAAM2,C5orf64,LILRA4,ZNF346,SYNPO2,ELP5,AMACR,ZMYND8,TUBB1,CLEC2L,AMOT,UBTF,PITPNB,PLEKHH2,BEST1,NSD2,ZNF24,FMN2,SLC26A10,ZBTB38,ZFAND5,CADM2,CSDE1,XKR7,PCDH15,TRIM16L,PARP11,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-216a:mirSVR_highEffct hsa-miR-216a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.34E-127 1.87E-123 3.69E-126 3.40E-125 329 1383 "VWA5B2,SDE2,ASIC2,CLK4,NCKAP5,SYS1,ARID1A,CSMD3,ADCY6,CDC7,SORCS1,PWWP2A,DPY19L2P4,KCTD16,OGT,LRCH2,GPAM,TNRC6C,LGR5,AQP4,AQP6,TMEFF1,ZFYVE28,ASCL1,STK33,NCOA1,ATP1B3,ATP2B1,RNF182,ATP6V0A1,BARD1,RGS9,DCAF5,DST,VXN,KRIT1,CCNH,LRRFIP1,MAGI1,CFL2,SOCS6,LSMEM2,TPP1,FBXO7,NIPBL,FAM149A,COL9A1,ZNF521,HS3ST5,CHD1L,CPS1,FAM171B,CREM,ENTPD4,VCAN,NCAN,SOCS5,CTNND1,CTNND2,USP6NL,KATNAL2,GAPVD1,TOX,TBC1D5,MATR3,KIAA0586,SPOCK2,DCC,PITPNC1,SPATA2,ELMSAN1,C8orf34,MYEF2,CNIH3,MAGI2,POM121,NR1D2,DPP6,DPYSL2,DRD1,PDCD6IP,DTNA,ECM2,DNAJB6,E2F6,EDIL3,FAM135B,SGK2,HIPK3,SEMA3D,FAM13A,PHF20L1,MBNL2,KMT5B,ABI2,EGR3,COPS4,ELAVL2,PLEKHA1,ING4,PAN3,EN2,OLIG2,RCAN2,MTSS1L,EPHA5,ADGRV1,F3,ARMCX1,FAM198B,FDFT1,GORAB,FGF1,POLR1B,FGF14,UBE2E3,ATP13A4,SGIP1,ERGIC3,NRG3,MEGF10,GABRA1,GABRA2,HRASLS5,GABRA3,GABRB1,GAD1,HBS1L,GALC,ZNF234,ZNF274,NEK6,NCKAP1,DISC1,LRRC37A6P,PPARGC1A,BRD8,COPS8,GLRB,GLS,MSL3,ZNF638,KDM2B,GOLGB1,GPD2,GPR19,EML4,NR3C1,GRM3,GRM7,BTN2A1,FAM19A2,AP4S1,HNF4G,TCEAL6,DHX35,HTR2A,HTR5A,IDH3A,C5orf24,DIPK1A,LRRTM3,NME9,JAK2,KCNB1,KCND2,KCNK2,KCNN1,CREG2,PAXBP1,ARHGAP12,MAP4,LYPLAL1,MEIS2,POC1B,MITF,CD200,SCG3,MTTP,MYO9A,ZNF862,HNRNPM,NAP1L1,NCAM1,NEK1,CNOT4,DNHD1,SLC11A2,NRGN,GPR88,OLR1,OPHN1,ZNF713,SNTG1,DPY19L2P2,PCSK5,PDE1C,GPR85,GNG2,BEST3,CDK14,GPSM2,ST8SIA5,PRIMPOL,ING3,EPB41L4B,FAT3,PPM1B,PPP2R5E,GRAMD1C,SNRK,PIGG,PTHLH,PTPRG,PTPRH,PID1,TMEM255A,SUSD4,RDX,SLC6A15,ERI2,GTDC1,RFX4,RGS12,SLC25A36,RNASEL,RPRD1A,SUGCT,DCUN1D2,ARMC5,GSTCD,SPIN3,MAP6D1,ATXN2,LINC00461,SCP2,FNIP1,SMPD3,SH3BGR,SH3GL3,SEC31A,ANKRD6,ZNF365,PREX2,DHX30,SLC6A8,SLC14A1,BTBD7,CPEB4,CDK5RAP2,ANKRD36,RIMS1,SNAP25,SNCA,UNC80,SOX2,SOX3,ZCCHC24,KIF21B,KDM3A,SP4,KDM4C,TAB2,ZSCAN29,ELOVL4,SEPT8,TTBK2,SYT11,ZC3H4,PRRC2C,SYN2,TAC1,PJA1,DDHD2,TAF6,UNC5D,ADGRL3,KIAA1107,TCEA1,DMXL2,CUX2,ZEB1,RPGRIP1L,WASHC4,CLASP1,WDR7,PCDHGA11,SYNE1,PCDHA5,AHCYL2,CCDC173,RNF216P1,CRB1,ITGB3BP,AP4E1,BHLHB9,ZFP91,NR2E1,KAT6B,RGMB,RUNDC3B,TRPS1,TSN,CADM1,PLEKHH2,CCDC14,TBC1D15,NSD2,XRCC4,ZIC3,MICU3,TCEAL7,ANKS1B,SYNC,SLC30A4,PMEPA1,EMSY,LINC02210,RNF103,ADAMTS9,VPS35L,FIP1L1,PDSS2,AMN1,MRPL47,RNF170,NETO1,ST8SIA2,SLC4A10" MicroRNA hsa-miR-15b*:mirSVR_highEffct hsa-miR-15b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.59E-127 2.02E-123 3.97E-126 3.65E-125 337 1450 "KCNH8,ABHD6,NCKAP5,XKR4,CSMD3,KLHL32,SORCS1,ERMN,KIDINS220,AP2A2,LRRC7,CEP126,GOLGA7B,OGT,USP28,PHF12,PPFIA2,PPFIA1,BCAS1,APP,SHTN1,AQP4,CASK,RGS20,ASPH,DDX3Y,CCDC181,SLC4A4,SEC11C,DCAF5,RAB29,WASF1,CA8,KALRN,PTBP2,SYT6,MAP7,CBR1,KRIT1,INA,LRBA,CDC42,L3MBTL4,MAGI1,CLGN,CHM,CHN2,CASC2,ZBED5,JAM2,PLAA,C4orf33,LETMD1,SLC4A7,ABI3BP,HS3ST5,CP,FAM171B,CLOCK,C2CD2,GDA,ABCG1,SEC24C,FEZ2,ARHGEF10,PDE4DIP,GREB1,DOCK4,PABPC5,PITPNC1,ZEB2,MFAP3L,FBXL5,C2CD2L,SPOCK3,DLG2,GRIN3A,DMD,DRD1,ABI1,PDCD6IP,FAM78B,DNM1L,GOLT1B,E2F5,EDNRA,ATL1,ANKRD46,FAM13A,LPAR6,ASB3,EML1,STARD3NL,DCTN4,EPB41L2,DMTN,KCNMB2,EPS8,ETV1,TLR7,SIRPB1,F5,CLVS1,RPS6KC1,TMEM132C,ACSL4,CEP78,FER,GTF2IRD2,FGF11,CAMSAP1,POLK,CAP2,SMC2,UFM1,TPK1,CAMKK2,KHDRBS3,CELF1,ST6GALNAC3,CHL1,GABRB1,ZMYND11,GAP43,ERAP1,DISC1,KIAA1841,SESN1,ADAM28,PPARGC1A,MALT1,GK,ZNF276,COPS8,DBF4,RAB30,PCDH11X,GNAL,LNX1,GPM6A,GPM6B,TDRKH,FUT10,CECR2,GRM5,CIT,LINC01551,AP4S1,GUCY1A2,RNFT2,RASSF8,HLF,SCRG1,HNF4G,ZDHHC15,SHISA6,HTR2A,IRF8,ZNF546,SCIN,IL11RA,ZNF678,JAK1,SLC35G1,KCNMA1,KCNN1,PAXBP1,PIK3AP1,MAP4,MAT2A,MBNL1,MEIS1,MIA2,KITLG,SESN3,CTNNA3,MYBPC1,NCAM2,NF1,NODAL,CNOT4,CHAMP1,OPA1,LOC100128398,GPR137C,PAH,PAK3,PRTG,NALCN,PIK3R1,CCSER2,ZFYVE21,ST8SIA5,PMP2,SCHIP1,EPB41L4B,SH3KBP1,C19orf57,DRAM2,MED1,PPM1B,PPP2R5E,PKIA,PKN2,HYDIN,DCHS2,LRRC49,SNRK,CNTLN,PLPPR1,BDNF-AS,TMEM260,STK32A,OCIAD1,PTPRG,FAM120C,PTPRZ1,PEX5,PPP2R3C,PID1,FAM66C,ENOX1,OXR1,RASGRF2,VEPH1,SLC6A15,ERI2,GTDC1,RFX3,UBR7,RIT2,SEC61A2,SLC25A36,PBRM1,RNASEL,CCDC82,TMLHE,CARF,PNMA8A,GSTCD,CCDC102B,LRRK2,PTGR2,RTN1,ZNF568,ZNF331,CSRNP3,LINC00461,SEC14L1,MRAS,COPZ1,SCG5,ZFP30,ITSN1,MAGI3,CHD9,ST6GAL1,PAAF1,WDR37,SLA,SLC1A6,PPP4R3A,RUFY2,CDK5RAP2,SNCA,UNC80,TRERF1,HECW1,KDM4C,SS18,RGL1,NECAB1,PRRC2C,NUDT10,SYP,COBL,DDHD2,UNC5D,ADGRL3,TBCEL,ATMIN,TCF7,TCF7L2,TRIM2,RPGRIP1L,WDR7,PCDHGA11,PCDHB10,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,C18orf54,ITGB3BP,AP4E1,AKTIP,GZF1,HEY1,TMPO,RIMBP2,C5orf64,TPD52,KCNE5,TMEFF2,CADM1,USP1,VLDLR,WIPF1,GUSBP1,XRCC4,ZNF19,ZNF70,GPR158-AS1,ZNF138,FSTL5,ZNF189,ANKS1B,CA10,EMSY,MFF,PRTFDC1,STMN4,ADAMTS9,NAV2,CAB39L,TRIM16L,MVB12B,GOPC,PAK5,PHTF2,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-140-5p:mirSVR_lowEffct hsa-miR-140-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.83E-127 2.15E-123 4.22E-126 3.88E-125 343 1501 "TTYH1,SYS1,XKR4,NDRG3,ADCY6,BRAP,AP2A2,MTUS1,PCDH19,KCTD16,TAOK1,ALAD,BBOX1,ANK3,CCDC146,ALS2,FAM131A,API5,SHROOM2,CDC14B,RGS20,DACT3,ZBTB10,ASTN1,CADM3,DOCK11,BCHE,RGS9,BCL2L2,BCL7A,BID,SYNJ1,FUBP1,JAZF1,RAB29,KALRN,VSTM2A,MAP7,LDB2,CDH8,LARGE1,NUMBL,SRSF11,CHGB,CHM,LHX2,NRXN3,TMEM155,CNR1,AKAP6,SLC25A27,BTF3L4,LETMD1,CREM,NCOR1,SIPA1L1,VCAN,KIAA0040,ARHGEF4,NRSN1,USP6NL,ARHGAP32,FGFR1OP2,HDAC4,EARS2,RASSF2,LONRF1,MATR3,KIAA0586,SCRN1,SPOCK2,PITPNC1,ZNF804A,ZEB2,KIAA0319,MAGI2,ZC3H11A,GUCD1,RHOBTB1,RABGAP1L,WDR20,DLG2,RAB39B,DMD,SLC12A6,PDCD6IP,DTNA,EDN1,EDNRB,SYT15,RBM12,EFNB3,PHF20L1,EGFR,KCTD3,COPS4,CALCRL,OLIG2,EPB41L1,LRRC17,EPHA5,EPHB1,GPHN,SRRM1,DENND4A,DNAJC27,KATNAL1,TUBB3,ST3GAL6,TOMM40L,STRADA,KAT8,ZNF589,GORAB,FECH,GTF2IRD2,FGR,SUCO,MEX3B,SEMA4D,ATP13A4,SGIP1,EFCAB2,UFM1,CAMKK2,ATP2C1,NSG2,NRG3,OGA,ARPP21,ZNF234,DISC1,ATP8A2,CYP46A1,SESN1,PPARGC1A,BRD8,GK,GLI2,TOX3,GLUL,ZNF638,KCNMB4,GNAS,ZNF782,CNDP1,GPD2,PRUNE2,PCLO,GRIA4,RFFL,GRIK4,NR3C1,GRM7,KIF3A,LINC00839,ADAMTS6,FAM222A,MAEL,ARHGAP19,ELOVL5,HMGB1,TLX1,EID2B,LINC00667,NKD1,RBPJ,LRRCC1,IL6R,LRRTM3,OLFM3,KCNC1,GPR62,KCNJ3,CREG2,KLRC2,CYP27C1,STMN1,LIMS1,LMO2,MAT2A,MATN2,CHIC1,SAMD5,ADAM22,MTR,PABPC1L2A,HNRNPM,NAP1L3,NDUFA5,NELL1,CCDC13,NEUROD1,NFYA,NME4,NOVA1,NTRK2,OGDH,OPHN1,PAX6,DPY19L2P2,PCSK1,PDGFRA,GPR85,PFKFB4,PIK3CD,PKM,SLC25A23,PURG,EXOSC10,RETREG2,POU3F2,PPP3CB,RANBP3L,MAPK4,MASP1,SLC22A23,WBP1L,SIDT1,MDGA2,QRICH1,ELOVL2,PTK2,PTN,PTPRE,FAM66C,FAT4,RAP1GDS1,ZNF493,OXR1,DBX2,KHDRBS2,ZYG11B,REV3L,ERI2,RFX4,ZDHHC4,RGS3,RNF220,SLC25A36,PBRM1,SUGCT,KLHDC8A,ROBO1,CCDC25,PCMTD2,CCDC102B,UEVLD,PRR5L,ACER3,WLS,KCNIP1,SEMA6D,SCN7A,CASC3,ITSN1,FAM102A,PPP1R9A,SH3GL2,MAGI3,FBXO11,WDR37,EPN2,LRRC55,SIRT2,SCMH1,SLCO1A2,CXXC4,INTS9,RCOR3,RIMS1,SNCB,KIF13A,UNC80,TNIK,SOX11,SP4,PEG10,KIF1B,NFASC,POGZ,ITPRID2,LRRC4,ERBIN,ST5,CEP68,KANK1,SEPT3,KLHL7,VPS13A,TMEM150C,MMS19,ATP11A,KAZN,CAMTA1,DNMBP,CAMSAP2,UNC5D,ACSL6,TCF4,ZFP90,CUX2,FAM189A1,PCDHB3,SIK3,DICER1,SLC44A1,GZF1,TJP1,TMPO,RIMBP2,C9orf85,ZNF346,TRIO,PDSS1,STXBP4,ZMYND8,SSBP2,TMEFF2,LINC00689,FLRT2,ZNF781,CLDND1,LYPD6,CELF4,POLR3H,ZNF189,DPYSL5,MAP3K12,CADM2,PRTFDC1,CSDE1,STOX2,SNX27,KCNAB1,FZD3,CASC15,FAM219B,TIGD6,FRMD6,NETO1,RNF146,AP3B2" MicroRNA hsa-miR-3189:mirSVR_lowEffct hsa-miR-3189:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.18E-127 2.91E-123 5.69E-126 5.24E-125 351 1571 "ABAT,SYN3,EMILIN3,ADAR,KLHL32,ADD2,PWWP2A,KIAA1211,RNF150,OLMALINC,MTUS1,NME5,CC2D2A,ABCD2,CARNS1,LRCH2,C6orf89,CNTNAP1,FAM131A,PPFIA3,LGR5,SHROOM2,AQP4,MIER1,CDK10,TMEM263,SPTBN4,ARHGDIG,ASPH,BRINP2,NUMB,TMEM108,EIF4G3,ATP6V0A1,ADAM23,TTLL9,ADGRB2,SNAI3-AS1,BCL7A,CFLAR,ARHGEF7,CASTOR3,CACNA1G,C5,OSGIN2,BSN,CA4,CACNA1B,CACNA1D,CABP7,VXN,CBLN1,CBR1,CBS,USP2,P2RX6,CDC27,LGI1,LARGE1,COPB2,RCBTB2,CHN2,EPS15L1,TPP1,FAM189A2,MAP4K4,CNGA3,WHRN,SUMF2,LETMD1,SLC4A8,SMARCAL1,IGDCC3,ZNF385A,CPS1,FAM171B,PNKD,SEC31B,CREM,ANKRD44,TENM4,CSF2RA,ARHGEF10,MICAL2,UBXN2A,PHF14,CFAP61,RUBCN,FAM131B,SEC14L5,CCDC144A,RIPOR2,TOX,DGKG,IP6K1,CEP170,SRGAP3,DNM1,HS3ST2,SLC29A4,SHANK1,DOCK2,CASP8AP2,ACOT8,DTNA,GOLT1B,E2F5,AASDH,ANKRD46,FCF1,TMTC1,APH1A,MBNL2,TMEM132E,RASA4,IRAK4,TENM1,EMX2,ANKRD13B,ERCC2,SPEG,MRPL37,EXTL2,ADGRV1,GMPR2,REEP2,TAOK3,DLC1,TOMM40L,FCGRT,TESK2,PPP1R1B,FER,GTF2IRD2,FGF1,FGF14,MAD2L2,SCARA3,FOXG1,CAP2,VTI1B,SORBS1,ZBED3,PDLIM5,ATP2C1,HRASLS5,GABRB3,HBS1L,BRPF3,RAPGEF6,GAP43,MTHFD2,LRRC37A6P,GGT5,GJB1,TXNL4A,GLI2,GLYR1,TNRC6A,GPR19,STON1,MCHR1,GRIK2,SPACA9,GRM1,RNFT2,SLC2A6,ATOH8,HAS2,PADI2,KLF12,BACH2,HPCA,SHISA6,RBPJ,SCIN,ITGA7,METTL21A,KCNC2,CAMK2N2,MAN2A2,MAP4,MAP6,MARK3,MATK,MATN3,MBD1,SYT9,ADAM11,LDLRAD3,MEIS1,KCTD6,MID1,MMP16,MOBP,NEUROD2,NFE2L2,NME4,SLC11A2,NTRK2,NTRK3,NUMA1,ODF2,OGG1,OPA1,ZNF827,ZDHHC22,SNTG1,PAK3,PCDH9,GPR173,PENK,PFKFB4,OLA1,PIK3R1,ZNF655,CCSER2,PKD1,ST8SIA5,JAKMIP1,PLP1,ANKRD16,STRN3,LRP12,PRRX1,NECAB2,EPB41L4B,PPARA,NKAIN4,MASP1,PSD,WBP1L,SYTL2,SIDT1,PIGG,CNTLN,BDNF-AS,CASTOR1,PTPRH,PTPRZ1,PID1,FAM66C,ZNF793,KHDRBS2,ZDHHC14,BSDC1,RGS3,RIT2,RLBP1,SEC61A2,RNF220,TMLHE,TMEM100,SNX22,RPL15,ADAL,RPS6KA2,SOX8,ST6GALNAC6,WLS,NCBP3,DGLUCY,MAPK12,SEMA6D,FAM19A1,FNIP1,SMPD3,ASIC4,SLC30A10,PEAR1,TRIM46,SELL,COPZ1,ITSN1,FAM102A,SH3GL3,PPM1E,ARX,AMBRA1,ST3GAL3,CTXN2,ANKRD6,ABLIM3,SLC1A3,PREX2,SLC6A1,KANSL3,LRRC55,SLC6A11,SLN,IFT122,INAVA,ZNF415,RBM34,WDTC1,SOX11,EMC1,KDM4C,DDN,TAB2,ITPRID2,MESP1,ZC4H2,NKAIN2,SULF2,SEPT3,ZFR2,SYP,SYT1,TBCEL,TBL1X,SMG6,ANO4,TCF12,WDR7,RALYL,ARHGEF12,RNF175,RNF216P1,VWCE,FAM200B,CRB1,ENHO,MTMR14,ACTR6,ZFP91,RIMBP2,CDK20,TPM2,ZNF384,ZNF346,SYNPO2,TRIO,NUTM2A,BCL2L13,CCDC14,ATP6V0E2,NDRG4,CRB2,ZBTB38,ZNF154,PCBP1-AS1,MEIS3,SEMA3B,NAV3,ST7,MARCH8,UBE3B,NUP214,TIGD6,CBLN2" MicroRNA hsa-miR-377*:mirSVR_lowEffct hsa-miR-377*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.87E-127 3.30E-123 6.44E-126 5.93E-125 356 1615 "KCNH8,ACHE,CSMD3,ADCY6,TMCC3,SLC12A5,KIDINS220,WDR35,TXNDC16,AK2,ALAD,SRPX,BCAR3,ABCD2,ZNF687,CNIH2,ANXA7,CACHD1,AMER3,PPFIA3,LGR5,AQP4,SFMBT2,SEMA4G,LINC00173,CDK13,MARCH3,DACT3,CHID1,EIF4G3,ATP2A2,DPY19L3,ADGRB3,BBS2,NRP2,CFLAR,FUBP1,LINC00906,SGCE,RAB29,CDK5R2,CA12,CACNA1B,CACNB4,BRSK2,PRC1,CDH8,LRRFIP1,LARGE1,GPR37L1,CHM,NRXN3,STOML1,SRP14-AS1,ARHGEF6,SLC25A27,SUMF2,LETMD1,COL9A3,ACBD5,ZFP28,MFSD4A,HS3ST5,ZNF385A,FAM171B,SNCAIP,OSBPL3,NCAN,VAC14-AS1,DZIP3,SDC3,PHF14,RIMS2,ST18,RIPOR2,PHF19,ZNF337,TM9SF4,ACY3,IST1,DGKG,B3GAT3,PLPPR4,SPOCK3,NTM,DLG4,RAB39B,HS3ST2,DOCK2,DPYSL2,RCAN1,GNE,DNAJB6,ABCC5,GOLT1B,SNX29,WDPCP,ATL1,PHF20L1,APH1A,EBI3,KMT5B,RASA4,TMEM35A,CALCRL,USPL1,EIF1,ENO2,EPB41L2,EPHB1,SIRPB1,ABCA8,ACSL4,CORO2B,CHST15,FGF14,BAIAP2,MEX3B,FOXG1,SEMA4D,FLT1,EFCAB2,PDLIM5,ERGIC3,KHDRBS3,NSG2,CELF1,STAU2,MSANTD4,DOT1L,ZNF512,PHYHIPL,DKK3,MEGF10,GABRA2,GABRB1,GABRG2,FAM120B,ZNF559,DISC1,LRRC37A6P,GGT7,GLYR1,MSL3,ZNF638,LUZP2,KCNMB4,GNAS,WDFY3-AS2,ADGRA3,EML4,PCLO,GRIA2,GRIA4,ADAMTS13,SERP2,GRIN1,ZNF496,LINC01089,ZBTB49,HAS2,TOX2,PADI2,ELOVL5,GABARAPL2,SYNPO,USP51,TCEAL6,HSF2,USP54,SCIN,LIX1,DIPK1A,TUBB2B,ITGA7,SLC35G1,OLFM3,KCNC1,KCNH1,IPO5,STMN1,PAXBP1,NCOA7,LSS,MAN2A2,MAP2,MAP6,MBD1,MBNL1,MBP,SYT9,SRSF12,AFDN,XRRA1,MMP16,MOBP,CD200,CCDC80,ADAM22,MYO7A,NAP1L3,NCAM1,NDUFA5,SFR1,NEFM,NEK1,NF1,NFIA,ALDH1L2,DNHD1,NPPA,NUCB2,ZNF713,PCDH8,PDE1C,PDE4D,PENK,CDK14,SMIM7,PLXNB3,PRIMPOL,PMP2,TRHDE,SPATA6,MINDY2,PPM1B,CRLS1,PPP3CB,NKAIN4,CEP41,PRKCB,EPDR1,WBP1L,ANKHD1,UHRF1BP1,TMEM260,OCIAD1,PTPRN,FAM120C,ZNF615,PPP2R3C,PID1,CEP97,RAD52,ARID4A,REV3L,PRRT2,SEC61A2,RPRD1A,RNH1,ALG9,YY1AP1,EPHA10,FBXW7,BAALC,ZNF671,RPS20,MEG3,ZNF568,RYR3,RMI1,S100B,SALL1,MIR124-2HG,ATXN7,SCN2A,SUPT20H,COPZ1,HSPA4L,ITSN1,ARX,MAGI3,BCAN,ST3GAL3,ABLIM3,LRRC55,RAB3GAP1,SLC8A3,SLC11A1,KBTBD4,SLC14A1,CPEB4,IFT122,ANKFN1,SNRPN,TMCC1,SCN3B,PDZD2,TRERF1,ZCCHC24,BDP1,SOX10,SP2,ENKUR,GLT8D1,SPTAN1,LHPP,SSPO,NEK4,RGL1,SYNE2,TMEM150C,COBL,ANKRD28,C12orf76,KAZN,MTCL1,CAMTA1,DNMBP,UNC5D,ADGRL3,TBCEL,FBXW11,KLHL4,DMXL2,SATB2,TCF7L2,TRIM2,PUM2,AHCYL2,SPX,ITGB3BP,AP4E1,ZNF34,FBXL16,TMOD1,PRRT1,TPM1,C9orf85,TRPC3,NTSR2,TSN,SSBP2,FRRS1L,WIPF1,CLDND1,ZIC2,TRIM9,SLC26A10,LYPD6,TCEAL7,PLPPR5,SMARCAD1,EMSY,RGMA,HPS4,CIAPIN1,PCDH15,NAV3,KCNAB1,DNAH10,FZD3,TMEM63C,CAMK1G,JMJD1C,CBLN2" MicroRNA hsa-miR-302a*:mirSVR_highEffct hsa-miR-302a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.43E-127 3.61E-123 7.04E-126 6.49E-125 340 1478 "CLK4,ARID1A,FMNL2,GALNT16,CCDC85A,ADCY8,TMCC3,BRAP,CDC7,PWWP2A,ADORA3,DPY19L2P4,MTUS1,PCDH19,HACE1,NME5,LRRC7,SEMA6A,PCDH10,UNC79,AMPD2,LRCH2,MAP4K3,PPFIA1,PARG,ALS2,FAM131A,CDK13,STK33,DDX3Y,CCDC181,STX16,B3GALT2,ADGRB3,BBS2,MPDZ,CDK5R1,SYNJ2,WASF1,IL33,CACNA1D,CACNB2,CACNB4,CABP7,PTBP2,VSTM2A,MAP7,KYAT1,CDH2,CDH8,L3MBTL4,LOC730101,DLGAP2,TIGD7,CCPG1,CASC2,NDST3,QKI,HECTD1,MAP4K4,NIPBL,IQCK,ARMC8,AKAP6,COL4A5,IFFO1,MYRIP,AKAP12,CS,CFAP61,FGFR1OP2,KATNAL2,GAPVD1,TCAF1,MATR3,DGKB,TMEM170A,DCC,YTHDC1,ZEB2,MYEF2,HP1BP3,CEP170,MAGI2,GSDME,SACS,G3BP2,WDR20,DMD,OLIG1,DNM2,DMTF1,DYRK1A,EBF1,WDPCP,EDNRB,FSD1L,OPTN,RBM12,FAM13A,LPAR6,COPS4,ELAVL2,PAN3,DCTN4,OLIG2,EPHA5,CDHR1,EXTL2,EYA1,F3,ARMCX1,TMEM132C,DLC1,ST3GAL6,GORAB,SLC9B2,FGF13,FGF14,AMOTL2,SUCO,MEX3B,HPCAL4,FOXF2,FLT1,SGIP1,EFCAB2,JKAMP,NBEA,STAU2,OGA,MEGF10,BRPF3,DISC1,DNER,ARFIP1,GHR,PPARGC1A,TXNL4A,GLYR1,GLS,TNRC6A,PRUNE2,GPM6B,GPR12,CECR2,GRIA1,GRIA2,NR3C1,WIF1,UBE2QL1,ELOVL5,SHISA6,MSL1,IDH3A,C2orf72,ZIC5,RBPJ,LRRCC1,LIX1,ZNF678,LRRTM1,OLFM3,KCNC2,KCNJ3,KCNMA1,CREG2,LAMP2,LIMS1,SMAD1,SMAD9,MAOB,MAP2,MARK1,LYPLAL1,MARK3,MBNL1,LRP1B,SHC3,MEIS1,SRSF12,MIA2,MOBP,ERICH3,PABPC1L2A,NELL2,NF1,NKX2-2,NNAT,NME4,NOVA1,SLC11A2,HCN1,CHAMP1,OXTR,GPR137C,GLIPR1L2,PDE3B,ANLN,PIK3CD,MTRF1L,MAPKAP1,LRP12,SCHIP1,PRRX1,ING3,RETREG2,SEPT4,TNPO2,NXPH1,PPM1B,LRRN3,PPP2R5E,RANBP3L,PRKCB,VPS13C,WBP1L,SNRK,MDGA2,CNTLN,ANKHD1,PTHLH,PTPRE,FAM120C,ZNF615,MARCH1,USP47,CCDC40,FAM66C,RET,ZFHX4,SETD5,TMLHE,RAVER2,GSTCD,ROBO1,ROBO2,RORB,PCMTD2,TMEM100,ARMH4,SPIN3,ADAL,LGR4,ABCA11P,FAM192A,AP1AR,FAM19A1,SCP2,ELMOD1,SH3GL2,ARX,MAGI3,AMBRA1,FBXO11,FNDC3A,CNKSR2,CCDC92,PPP4R3A,SLC15A2,TET1,SMARCC2,SMARCE1,RCOR3,LIMCH1,SNAP25,SNCA,SNRPN,PALLD,PDZRN3,SON,PDZD2,MYT1L,KDM3A,EMC1,PEG10,RBM26,SPART,NFASC,SRPK2,PBLD,COLGALT2,SSTR2,NKAIN2,NXT2,SULF2,ACSBG1,SYNE2,SYT1,ANO4,ZEB1,RALYL,SLC19A3,AKNA,PUM2,CCDC173,PMS2CL,DICER1,ITGB3BP,ZMAT3,TLR4,KAT6B,TRO,TRPC1,ZMYND8,SGK3,ZNF610,OSBP2,CCDC14,TBC1D15,WIPF1,ZNF781,XPO1,ZNF711,ZNF24,FMN2,MKRN3,ZBTB38,ZNF189,PLPPR5,UPF3A,WNK1,CA10,EMSY,CADM2,CSDE1,STOX2,ADAMTS9,SNX27,FIP1L1,PLSCR4,FAM13C,AMN1,RTN4,UBE3B,PHTF2,ACTR3B,ADAMTSL3,RNF170,FXR1" MicroRNA hsa-miR-29c:mirSVR_lowEffct hsa-miR-29c:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.73E-127 4.91E-123 9.53E-126 8.78E-125 360 1652 "VWA5B2,ABCF1,ACADM,CLK4,SYS1,NDRG2,FMNL2,ADCY2,SLITRK1,SORCS1,KIAA1211,RNF150,OLMALINC,ZNF608,ZNF578,LRRC7,SEMA6A,CARNS1,ZFAT,CDC42BPA,LRCH2,ANK3,FGD2,CCDC146,KCNAB2,DGKZ,UPRT,DGKD,PHYHD1,TNRC6C,USP37,SHROOM2,CDC14B,CDK10,ARHGAP5,ARHGDIG,ARSF,MARK4,ZBTB10,DDX3Y,ATM,DOCK11,ADAM15,SYNJ2,MTMR2,JAZF1,LDLRAD4,CA4,CACNA1A,CACNA1E,KALRN,CAMK2G,CANX,BRSK2,ARHGEF25,CD81,CDC42,DCLK1,LRRFIP1,L3MBTL4,UBE2L6,CFL2,SRSF11,CASC2,SYNPR,B4GALT6,CHRNB2,CNOT8,EPS15L1,KIAA1549L,NMT2,CLTC,FBXO7,QKI,SULT4A1,NIPBL,WHRN,BTF3L4,AKAP5,IFFO1,MFSD4A,CP,NCOR2,ARHGEF10,CSNK1E,OSBPL3,ATRNL1,IPCEF1,PDE4DIP,PLXNA4,ERC2,PNPLA8,GREB1,CTNND1,NRSN1,DCAF4,FAM131B,CYBB,HDAC9,ARHGAP32,KATNAL2,RIPOR2,HDAC4,TOMM20,IP6K1,BRINP1,SIRPA,ARMCX4,ELMSAN1,DDX46,ALKBH8,PLPPR4,WDR20,DLG2,CDON,FAM57B,DPYSL2,ABI1,ARRDC4,SGK2,SEMA3D,SIDT2,EFNB3,LPAR6,GOLGA7,KCTD3,PLEKHA1,C8orf37,MTSS1L,SEZ6,ENPP6,ERCC2,NCALD,SPEG,MRPL37,CLVS1,WAC,POLR1B,FGFR1,HPCAL4,SYNCRIP,FOXO3,SEMA4D,PSD2,COQ5,ZCCHC17,SMC2,TRIM16,ST6GALNAC3,STAU2,KBTBD12,MSANTD4,GAP43,ERAP1,SRCAP,PCDH17,PPARGC1A,DBF4,GLI2,PCDH11X,STARD3,POLL,GNAS,GP1BB,DIPK1C,PRLHR,CCDC184,STON1,CECR2,GRB10,GRIA2,C1QL4,GRIA4,GRIK2,ADAMTS13,NR3C1,GRM1,RNF165,GSTM5,WIF1,MUM1,RASSF8,ARHGAP19,MIER3,HLF,ELOVL5,SYNPO,HNMT,NEGR1,FAM95B1,ZIC5,KNDC1,KIAA1755,INPP5B,TUBB2B,ZNF385B,KCNC2,KCNJ16,KIF5C,TTYH2,LAMP2,LIFR,SYTL4,VWA5A,MAT2A,AQP11,SCAMP5,MKLN1,MOG,ERICH3,COL28A1,COMMD5,MTR,RTL5,NEFM,NFIA,NFE2L2,NFIX,NPPA,HCN1,OXTR,P2RY1,KCNK10,PALM,PAX6,PCMT1,CDK18,PDE3B,PIK3R1,PKD1,KCTD15,MTRF1L,STRN3,EXOSC10,SCHIP1,RETREG2,WBP1L,SIDT1,PIGG,UHRF1BP1,EML5,FAM120C,PEX5,NKAIN1,TUG1,CEP97,TMEM255A,SLC25A48,FAM66C,SH3TC2,ZCWPW1,RDX,ZYG11B,TRIM68,RET,ERI2,GTDC1,RGS3,RIC8B,ZFHX4,SETD5,KIRREL1,ROBO2,YY1AP1,SNX22,KIAA0895L,GLDN,STK32B,PAQR6,ABCA11P,KCNIP2,STX1B,FAM182A,HOGA1,SMPD3,GALNT10,KIF21A,PPM1E,FRMPD1,DOCK10,FNDC3A,ZNF365,RPH3A,PKNOX2,SLC6A8,SEPHS1,SLC20A2,LGI3,NAXD,SORCS3,TTC17,MAPKBP1,MBD5,SNRPN,SCN3B,DOP1A,SON,ZSWIM8,ERC1,UNC5B,PEG10,ZBTB43,C11orf87,ZNF302,ERBIN,CEP68,ADHFE1,STX1A,NSFL1C,ZC3H4,SUPT5H,ADAMTS17,SYN2,C12orf76,ATP11A,TACC1,CAMSAP2,VWA3A,SIN3B,SATB2,ZFP90,TRIM2,SYNE1,USP32P1,GPRIN3,HIF3A,GPR161,TIAM1,ZFP91,DAAM2,C5orf64,LILRA4,ZNF346,SYNPO2,ELP5,AMACR,ZMYND8,TUBB1,CLEC2L,AMOT,UBTF,PITPNB,PLEKHH2,NSD2,ZNF24,FMN2,SLC26A10,ZBTB38,CADM2,PRDM2,CSDE1,XKR7,HPS4,PCDH15,GAL3ST3,TRIM16L,UBE3B,PHTF2,ADAMTS10,FRMD6" MicroRNA hsa-miR-510:mirSVR_lowEffct hsa-miR-510:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.74E-127 4.91E-123 9.53E-126 8.78E-125 382 1849 "SDE2,ABAT,SYS1,ACTN2,GPRIN1,CSMD3,KLHL32,ADD2,SLC12A5,PNMA8B,PLEKHH1,ADORA2A,SNX30,RNF150,ESYT2,ADRA1D,LRFN2,BEND6,SLC24A4,AP2A2,PCDH19,KIAA1324,CC2D2A,SEMA6A,SPOP,PCDH10,AMPD2,ANK2,EP400,DGKD,ALS2,PPFIA3,MADD,ASCL1,MARCH3,CAPRIN2,INSYN2B,EIF4G3,B3GALT2,RIPK1,ADAM23,BACH1,SEC11C,OSGIN2,MYRF,CACNA1B,PTBP2,CAMK2D,CAST,HIP1R,PRC1,CBR1,ZNF501,METTL6,USP2,ARHGEF1,REPS2,CDC27,ZNF445,NUMBL,GPR37L1,NDST3,FAM19A5,SUMF2,COL9A2,SLC4A7,TENM4,LRRC3B,CSNK1G3,SIPA1L1,PDE4DIP,PHACTR3,SDC3,PHF14,GREB1,PUM1,CCDC144A,DOCK4,DCAF8,RASSF2,TM9SF4,RIMS3,TMEM170A,SCRN1,DCC,PITPNC1,SPATA2,ZEB2,HEPH,KIAA0753,SV2B,TMCC2,ZNF582-AS1,DMD,ARRDC4,DTNA,DNAJB6,AASDH,EDIL3,SGK2,RASGRP1,FAM13A,APH1A,EGFR,EGR3,TMEM132E,ELAVL4,DCTN4,OLIG2,ENPP6,TMEM74,CEND1,KATNAL1,MRVI1,CLVS1,ZNF461,SCML2,FCGRT,ZSCAN30,FDFT1,ZNF589,FER,FGF11,FGFR1,CAMSAP1,FHL1,UBE2E3,SEMA4D,SORBS1,ERGIC3,NSG2,CELF1,FYN,GABRB1,HBS1L,ZNF274,GHDC,SRCAP,SULT1C4,GPR162,GFAP,GGT7,PPARGC1A,TTBK1,CRCP,DBF4,TOX3,PCDH11X,DCLK2,DIPK1C,GPR17,SPACA9,RNF165,ZBTB49,BVES,MFSD2A,SOX21,PSIP1,ADAMTS6,NXPH2,ARHGAP19,HLF,HMGCL,HNMT,NEGR1,CPT1C,SHISA6,HSP90AA1,EID2B,IRF8,IDH3A,LRRC25,USP54,SLC6A17,INSM1,ITGAM,KCNB1,KCNJ3,STMN1,SYTL4,HECTD2,GPR155,MAP6,MDM4,MEIS1,KITLG,PPM1L,AFDN,XRRA1,MN1,ZNF680,SAMD5,ADAM22,MSR1,MYBPC1,MYO6,ZNF862,HNRNPM,NELL2,OTOGL,ALDH1L2,NODAL,NOVA1,DNHD1,SLC11A2,NTRK2,NTRK3,NUCB2,TBC1D25,ODF2,OGDH,OPHN1,CLDN11,ZNF713,GLIPR1L2,PCSK1,CDK18,ENPP2,PFKFB4,NALCN,PIK3C2A,NOMO2,A2ML1,ZFYVE21,XRN1,PLCD1,ANKRD16,SDK2,NECAB2,TNPO2,NXPH1,PPM1B,TATDN3,PTPA,RAB39A,PRKCG,PKN2,GRAMD1C,BCAS3,VPS13C,WBP1L,CYBC1,APTX,UHRF1BP1,MTMR10,ZIK1,PTPRG,C1orf109,TUG1,QDPR,FAM66C,ZNF493,RASGRF1,RASGRF2,DBX2,BSDC1,CRTAC1,TRIM68,RNASE1,RIC8B,RNASEL,CARF,YY1AP1,MRAP2,EPHA10,GLDN,ACER3,RPS20,KCNIP3,KCNIP2,SEMA6D,SBF1,ATXN2,HOGA1,PRCD,ASRGL1,TRA2B,COPZ1,KIF16B,SHMT2,FNDC3A,SEC31A,ST8SIA1,DZIP1,ANKRD6,PAAF1,ZNF365,DHX30,SMTN,KDM4D,ARHGEF40,CCDC88A,TRIM67,LGI3,NAXD,ZKSCAN3,ANKRD36,RIMS1,CABCOCO1,SNRPN,FAM126B,SCN3B,SOX3,TSNAXIP1,FNBP1,NMNAT2,HECW1,MYCBP2,KDM4C,SPTAN1,IQSEC2,MCF2L2,NFASC,ZC4H2,LRRC4,MAPK8IP3,STAU1,FGD4,VPS13A,SYN2,SYT1,SEMA4A,TAL1,FAM208A,ALG1,TMEM136,EHBP1,TCF4,CLASP1,DOCK9,SLC19A3,AKNA,PUM2,FRYL,DICER1-AS1,AP4E1,TIAM1,MTMR14,NACC2,TMOD1,PIK3R5,RASD2,ZNF346,SYNPO2,METTL3,SMUG1,ELP5,TRPS1,HEPACAM,DNAJC12,BCL2L13,PLPPR2,BEST1,ZNF19,ZNF28,TRIM9,SLC26A10,LYPD6,UPF3A,SLC30A4,GDPD5,LINC02210,STOX2,LMAN2L,SLC17A7,WNK3,PLSCR4,FZD3,DOCK8,UBE3B,KAT6A,PHTF2,CERS6,ADAMTSL3,ZNF248,TTC7A,FXR1,CBLN2,SLC4A10,GAN,FAM198A,SENP7" MicroRNA hsa-miR-382:mirSVR_highEffct hsa-miR-382:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-126 5.72E-123 1.11E-125 1.02E-124 329 1388 "CLK4,TKTL1,ACTN1,ARID1A,KLHL32,GALNT13,SORCS1,ERMN,PWWP2A,KIAA1211,BEND6,SNX32,RTL9,TXNDC16,TAOK1,C1QTNF3,ALCAM,BCAR3,FAM135A,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,GPAM,BCAS1,API5,SHTN1,MIER1,ARNTL,PDE8B,CAPRIN2,DDX3Y,ATP1A2,EIF4G3,ATP2B1,NOL4,DPY19L3,ADAM23,SEC11C,ZNF599,ARHGEF7,IL33,CACNA1B,MAP7,RUNX1T1,USP2,RGN,LRBA,CDH10,CDH18,LOC730101,TIGD7,LRWD1,CFL2,FOXN3,SOCS6,KMT2C,CLU,CLTC,QKI,AKAP7,IQCK,SLC25A27,SLC4A8,CNRIP1,HS3ST5,CP,CHD1L,SLC35F1,CPS1,FAM171B,CRHBP,CSF1,CTNND2,PUM1,HDAC9,TOX,IST1,ZEB2,ZBTB24,FBXL5,DDX46,SV2B,SPOCK3,G3BP2,WDR20,GRIN3A,DMD,HS3ST2,DPH1,ARRDC4,DTNB,ABCC5,DNM1L,EBF1,EDN3,EDNRB,HIPK3,RASGRP1,YAF2,PHF20L1,MBNL2,TENM1,PLEKHA1,TMEM35A,EN2,RCAN2,SEZ6,ENPP6,SRRM1,RCSD1,EXTL2,EYA1,ZIC4,SCML2,DLC1,FDFT1,GORAB,SLC9B2,FER,KIAA1109,AMOTL2,POLK,SUCO,CAP2,IP6K2,SYNCRIP,NBEA,CELF1,OGA,STAG2,GABRA5,GABRB1,ZNF234,C15orf41,ATP8A2,KIAA1841,PPARGC1A,RAB30,STARD3,DCLK2,WDFY3-AS2,GPD2,STMN2,GRIA2,GRM1,LINC01551,ZHX1,PACSIN2,AGBL5,NEGR1,OPALIN,CELF5,IFI16,SOWAHA,ZIC5,LRRCC1,LRRTM3,ITGAM,OLFM3,KCNC2,KCNJ3,KCNN2,IPO5,STXBP5,INSYN2,LMO2,SYTL4,ZFYVE27,LYPLAL1,MATN2,MATN3,MBNL1,SRSF12,MEST,MID1,MMP16,COL28A1,MRPL42,RSPO2,LAYN,MYO9A,RTL5,NAP1L1,SFR1,IDNK,OTOGL,VWA2,OGDH,CLDN11,OXTR,TREM2,PCDH9,PCSK5,PDPK1,GPR85,BEST3,NALCN,A2ML1,PMP2,LRP12,ING3,EPB41L4B,NXPH1,CCDC144B,LRRN3,PPP2R5E,PPP3CC,PKIA,CNNM2,VPS13C,UHRF1BP1,TMEM260,PTPRD,PTPRE,FAM120C,ZNF615,FAM66C,OXR1,RASGRF2,SLC6A15,ZYG11B,ERI2,GTDC1,FIGN,RFX3,SEC61A2,ROBO1,ROBO2,CCDC102B,MRAP2,ATP8B4,PRR5L,TCP11L1,LRRK2,LGR4,TRAPPC13,ATXN2,SCN3A,FAM19A1,SCP2,IL17RB,NLGN4Y,SGK1,KIF21A,SHC4,MAGI3,SYBU,ANKRD6,SLC1A3,BTBD3,SLC6A8,SLC6A11,SPHKAP,SORCS3,SNRPN,SOX2,SOX5,KDM3A,ENKUR,PEG10,KIF1B,RBM26,NPAS3,ITPRID2,SSTR1,EPB41L3,SEPT8,CEP68,KLHL7,SYNE2,VPS13A,SYT1,COBL,SYT4,CAMTA1,TMEM136,ANO4,SYNE1,TMEM151B,TEX15,SIK3,RNF216P1,DICER1,CRB1,TGFBR3,TIAM1,DDHD1,ERCC6L2,FAM124A,ZNF346,SYNPO2,STXBP4,RFTN2,ZKSCAN5,CLHC1,SGK3,TUBB1,ZNF610,CADM1,FAM155A,EIF4ENIF1,UBE2H,AMOT,UBTF,SLAIN1,USP1,VSNL1,CLDND1,XPO1,ZNF708,ZNF19,TRIM9,ZNF138,ZBTB38,REEP1,FSTL5,EML6,PLPPR5,SMARCAD1,SYNC,WNK1,NAV3,LINC00632,SLC17A6,GOPC,PHTF2,CASC15,NETO2,SLC4A10" MicroRNA hsa-miR-19b-2*:mirSVR_highEffct hsa-miR-19b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-126 8.49E-123 1.64E-125 1.51E-124 321 1324 "ARID1A,CSMD3,SORCS1,KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,ANK3,USP28,GPAM,VAT1L,API5,APP,SHTN1,PPP4R4,SPTBN4,NUMB,EIF4G3,B3GALT2,NOL4,BACH1,BCL7A,ARHGEF7,LINC00906,MTMR2,SGCE,OSGIN2,IL33,CACNA1B,CACNA2D1,CALM1,KALRN,PTBP2,CAMK2D,CAMK2G,VSTM2A,CAST,CDH8,LRRFIP1,NOG,CACNA2D2,CFL2,CBARP,CHGA,SOCS6,CHM,CASC2,JAM2,NRXN3,PLAA,PPT2,CLCN4,NRXN1,FBXO7,FAM189A2,C4orf33,NIPBL,ARMC8,RCHY1,MYRIP,IGDCC3,MFSD4A,CP,SLC35F1,FAM171B,CLOCK,FEZ2,MICAL2,SUSD5,PLCH2,PLXNA4,PHF14,CTH,CTNND1,ST18,USP6NL,ARHGAP32,FRMPD4,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,CEP170,MAGI2,RHOBTB1,AK5,FAM107B,NR1D2,CPEB2,ABI1,DTNA,EDN1,EDN3,EDNRB,RASGRP1,PHF20L1,EGFR,EIF4G2,ELAVL4,EMX2,LRRC17,CEP85L,CDKL3,RTN3,TLR7,CACNG2,TMEM132C,TAOK3,DLC1,TOMM40L,FDFT1,SUCO,CAP2,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,NPTN,ATP2C1,CELF1,PHYHIPL,MEGF10,CHL1,CAB39,GAD2,HBS1L,MTHFD2,ATP8A2,GATM,NEU3,ARFIP1,AHDC1,ADAM28,TXNL4A,GLI2,GLRB,ZNF638,GNAO1,FERMT2,GRB10,GRIK2,PTPN5,SOX21,HAS2,FRMD3,ARHGAP36,HNF4G,NEGR1,SHISA6,LIX1,KCND2,KCNK2,KCNN3,STXBP5,LAMA2,PAXBP1,VWA5A,ASPRV1,PIK3AP1,MARK1,MATN2,SYT9,EFHB,KCTD6,MIA2,PPM1L,MITF,MOG,ZNF680,MYO9A,NAP1L1,NAP1L2,SFR1,NF1,NFE2L2,SMIM11A,OGG1,OPA1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,PDE4D,GNG2,OLA1,NLGN3,FAM218A,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,SLC36A4,POU3F2,PRKCB,MAPK10,HYDIN,SIDT1,ELOVL2,PTK2,PTN,STK32A,PTPN13,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RNF220,RNASE1,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,RPE65,TMEM100,SPIN3,MCMBP,ACER3,ABCA11P,HSD11B1L,RTN1,FAM182A,SATB1,ATXN7,SCN7A,FNIP1,KIF21A,SH3GL2,CPEB3,NTNG1,CTXN2,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,PALLD,MYO16,UNC80,SOX5,KDM3A,SP4,ZC3H13,ZC4H2,NXT2,RGL1,SYT11,VPS13A,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,WASHC4,PCDHB9,OBSL1,PUM2,FRYL,CRB1,GZF1,ASXL3,NR2E1,TMPO,C9orf85,TPM4,SYNPO2,TRO,TRPC1,ANKRD20A2,TUB,TMEFF2,TUBB1,RPL7L1,FAM155A,VLDLR,P2RY12,NSD2,GUSBP1,XPO1,XRCC4,CFAP298,ZNF28,KCNT2,ZNF540,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,ZNF195,SPIRE1,CA10,PRDM2,CSDE1,STOX2,TMEM178A,NAV3,SLC17A6,PDSS2,FZD3,KLHDC1,SLC4A10" MicroRNA hsa-miR-1979:mirSVR_lowEffct hsa-miR-1979:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.55E-126 8.70E-123 1.68E-125 1.55E-124 395 1972 "AS3MT,CSMD2,NDRG2,ADAR,TMEM132B,ADCY6,GRAMD1B,ADORA2A,KIAA1211,ADRA1D,AP2A2,TAOK1,SEMA6A,BCAR3,PDZD4,AMPD2,OGT,FGD2,SUGT1P4-STRA6LP-CCDC180,ANXA7,UPRT,GPAM,ALS2,APP,AQP6,MARCH3,MARK4,ATP1A2,SLC4A4,EIF4G3,STX16,ZNF583,DPY19L3,TTLL9,LINC00847,BCL2L2,DCAF5,MTMR2,BSN,CACNA1B,CACNA1E,DDR1,CACNB2,CACNB4,CALB1,KALRN,HAP1,CAMK2A,CAMK2G,BRSK2,CLDN10,SLC16A4,CD38,C1orf52,CD81,CDH2,LGI1,CHRM1,CASC2,CHRNB2,C7orf61,CLCN4,FBXO7,QKI,HECTD1,TMEM155,COL4A5,COX4I1,MFSD4A,HS3ST5,CHD1L,CRY2,CSF1,LRIG1,CSNK1E,VAC14-AS1,SLITRK5,NRSN1,TCAF1,ARHGAP24,DCAF8,FRMPD4,PHF19,KCTD8,IST1,DGKB,TOMM20,SCRN1,IP6K1,DBI,B3GAT3,KIAA0753,COPS7A,MED24,GUCD1,PLPPR4,G3BP2,DLG2,DLG4,GRIN3A,RAB39B,HS3ST4,DOCK2,PDCD6IP,RCAN1,TOM1,ABCC9,SEZ6L2,FCF1,CNNM1,RASGRP1,YAF2,SH3GLB1,CELSR3,GPR61,MBNL2,ABI2,SORBS3,EIF5,DCTN4,COQ7,DMTN,LRRC17,RABEPK,ZNF549,ETV1,RTN3,NRN1,F5,CLVS1,ABCA8,ZNF461,FABP7,CACNG2,ATP8A1,CEP78,FCGR3A,TOMM40L,FKTN,FDFT1,ZNF589,FGF1,OLFM1,SPSB4,FOXF2,SYNCRIP,FLNC,SGIP1,SORBS1,NPTN,ATP6V1H,NSG2,KBTBD12,OGA,MEGF11,GABRA1,HRASLS5,GABRG1,TMEM8B,DISC1,ATP8A2,LRRC37A6P,ALDH1L1,GCNT2,GGT7,GJB1,CRCP,GNAL,GPD1,ATF7,PCLO,PLCD4,GRIK3,GRM1,GRM5,CLASRP,FAM19A2,RNF165,PSIP1,MAN1B1,NCKAP1L,ARHGAP36,ELOVL5,HMGB1,SYNPO,CPT1C,OPALIN,HSD17B1,SHISA6,FAM95B1,IDH3B,C2orf72,NKD1,KIAA1755,IL6ST,INPP5B,KCNA1,KCNJ10,KIF5A,A1BG-AS1,IPO5,STMN1,SYTL4,FGFBP3,NCOA7,C2orf80,PACRG,GPR155,MAP4,SYT9,CHST6,TM6SF1,MMP16,MOBP,MOG,GIT1,MRPL42,BLOC1S2,CTNNA3,RTL5,NEXMIF,ZNF862,NAP1L1,FXYD6,NF1,NOS1,NPTX2,OPHN1,CLDN11,ZDHHC22,SNTG1,PBX1,DPY19L2P2,PDE1C,PDGFRA,PENK,OLA1,ABCB1,ZNF655,CCSER2,PLCB2,PLXNB1,PURG,C11orf49,ANKRD16,STRN3,EPB41L4B,TNPO2,TMEM235,TATDN3,RASGEF1B,PRKCB,MASP1,NDUFS7,MDGA2,PIGG,OCIAD1,PTPRO,ACSM5,USP47,RALGDS,RASGRF1,CRTAC1,ZMAT4,TRIM68,RFX2,RFX4,RGS3,RIC8B,PBRM1,LGI2,SUGCT,TMLHE,ALG9,ARMC5,GSTCD,ELP2,EPHA10,SPIN3,GLDN,SGSM1,TCP11L1,MAP6D1,LGR4,MEG3,ATAT1,KCNIP3,RTKN,FAM182A,FAM192A,DRAXIN,ATXN7,ASIC4,ZFP2,SGK1,KIF21A,FERMT1,CHD9,ST6GAL1,ST3GAL3,WDR37,ABLIM3,SLA,SLC1A3,PPP4R3A,DHX30,PKNOX2,LRRC55,SLC6A7,SLC6A8,SLC8A2,ARHGEF40,SLC9A5,SLC14A1,NAPB,COA1,INTS9,MAPKBP1,SNRPN,PALLD,UNC80,RBM34,USP33,SON,WDTC1,ZCCHC24,KIF21B,BDP1,SP4,ENKUR,TEX2,UNC5B,PEG10,ITPRID2,NKAIN2,PHLDB1,SEPT3,NSFL1C,NECAB1,COBL,AGTPBP1,TBX15,EHBP1,SIN3B,TCF7L2,SLC19A3,USP32P1,GPRIN3,HIF3A,CYB561A3,C18orf54,TGFBR3,ZNF106,GALNT17,RELL2,ACTR6,TLR4,ERCC6L2,HEY2,CSMD1,TNR,RBFOX2,NR2C2,TRO,TSN,ANO5,CADM1,FAM155A,UBE2H,VIPR2,NSD2,PORCN,RICTOR,GUSBP1,ATP6V0E2,FMN2,CRB2,SPIRE1,ZNF213,UPF3A,EMSY,STOX2,ADAMTS9,PPP1R3F,FIP1L1,CAB39L,WNK2,PDSS2,GOPC,HNRNPA3,CASC15,ZNF248,TTC7A,GAN,FAM198A" MicroRNA hsa-miR-3140:mirSVR_highEffct hsa-miR-3140:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-126 1.01E-122 1.94E-125 1.79E-124 327 1374 "AS3MT,ADD3,BRAP,PTCHD1,MTUS1,KLHL13,OSBPL1A,PCDH10,DPP10,LRCH2,LCORL,MAP4K3,AQP4,MIER1,PPP4R4,IGDCC4,ZSCAN18,NUMB,N4BP2L1,TTLL9,ADGRB3,CFLAR,PROM1,SYNJ1,ARHGEF7,CASTOR3,SGCE,PTBP2,CAMK2G,CAST,MAP7,RUNX1T1,PRC1,SLC16A4,AIFM1,TMEM257,CD38,DGKI,REPS2,CDH2,LRRFIP1,LGI1,MAGI1,NOG,CHN1,CHN2,CASC2,CNOT8,NDST3,NRXN3,COG1,CLTA,TJP2,HECTD1,ARMC8,AKAP6,LETMD1,ABI3BP,TOGARAM2,MYRIP,IGDCC3,SLC35F1,FAM171B,CRMP1,ANKRD44,GDA,LRRC3B,ARHGEF10,OSBPL3,ATRNL1,VCAN,SDC3,KATNAL2,RIPOR2,ARHGAP24,CENPL,LIN54,KCTD8,DCC,DNAJC6,JAKMIP2,ZEB2,MYEF2,MAGI2,FBXO25,LYPD1,DDX46,SPOCK3,DLX1,HS3ST4,HS3ST2,USP3,DNAH9,DYRK1A,GOLT1B,E2F5,EBF1,WDPCP,EDN3,FRY,RBM12,PHF20L1,EGFR,EML1,CALCRL,EPB41L1,LRRC17,MTSS1L,EPHB1,KCNMB2,ERBB2,DENND4A,EYA1,ABCA8,FAM198B,ZNF461,CACNG2,ZIC4,FER,FGF1,FLT1,NOP56,NELFCD,C2orf88,ZCCHC17,APOPT1,STAMBP,KHDRBS3,SARAF,NRG3,ZMAT1,GABRA1,ZMYND11,ARPP21,GAP43,ERAP1,ALDH1L1,PCDH17,GLUL,ZNF638,CBX1,GNAS,ZNF782,FERMT2,ATP2B1-AS1,GRB10,GRIA2,GRM3,GRM5,CIT,FAM19A2,COQ10A,RASSF8,UBE2QL1,C1orf94,ZHX1,NEGR1,CELF5,ICA1,MSL1,RBPJ,LRRTM1,KCNK1,KCNK2,KCNMA1,KIF5A,STXBP5,KTN1,LAMP2,INSYN2,PAXBP1,HECTD2,LYPLAL1,MBP,SYT9,EFHB,POC1B,CTNNA3,RSPO2,MYO9A,NCAM1,NEFM,NEUROD1,NF1,HCN1,NUCB2,ODF2,OPCML,P2RY1,GPR137C,SNTG1,CNTN3,PCDH9,PCSK5,PDE1A,PDE3B,PDE4B,HERC2P3,PCDH18,HMGCLL1,TRHDE,FAT3,SH3KBP1,CRLS1,PPP2R5E,PRKCB,PKN2,GRAMD1C,HYDIN,PRPSAP2,RELN,PIGG,PTN,RIPOR1,ZNF493,OXR1,ARID4A,RBBP6,VEPH1,ZMAT4,ERI2,RNASEL,RPRD1A,SETD5,CARF,ROBO2,RORB,TMEM206,RPE,NEK11,FBXW7,ABCA11P,ATAT1,KCNIP3,RTKN,CLIP1,TRAPPC13,MIR124-2HG,ATXN7,SCN7A,HES6,ELMOD1,PPM1E,DOCK10,SHC4,SEC31A,ANKRD6,ZNF365,PPP4R3A,DHX30,WDR47,SLC6A8,NAXD,SMARCE1,ANKRD36,LIMCH1,RIMS1,KIF13A,SNRPN,PALLD,USP33,SON,PDZD2,MYT1L,SOX3,BDP1,EMC1,HECW1,KDM4C,UNC5B,RBM26,ATP10B,SEPT8,STXBP1,VPS13A,PLCB1,PJA1,CAMTA1,ADGRL3,ANO4,TCF7L2,RPGRIP1L,SZT2,RALYL,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,ZFPM2,AP4E1,ZMAT3,SLC44A1,TJP1,ZFP91,NR2E1,ERCC6L2,TMPO,C5orf64,SYNPO2,TSC1,TMEFF2,RPL7L1,PITPNB,MEAF6,BEST1,VSNL1,P2RY12,NPDC1,SLC13A3,ZSCAN26,LAMP5,PRTFDC1,LMAN2L,VPS35L,GAL3ST3,FIP1L1,CAB39L,SLC17A6,C12orf4,AMN1,UBE3B,PAK5,FRMD6" MicroRNA hsa-miR-1293:mirSVR_lowEffct hsa-miR-1293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-126 1.04E-122 2.00E-125 1.84E-124 330 1399 "KDM5D,CSMD2,ADARB2,KLHL32,PLEKHH1,ADRA1D,OSBPL1A,SORCS2,CC2D2A,SPOP,LTBP4,ALK,SUGT1P4-STRA6LP-CCDC180,APBA2,KCNAB2,PPFIA3,SEMA4G,SPTBN4,PLA2G4C,NCOA1,NUMB,NOL4,BBS2,GYG2,DDR1,CALB2,KALRN,METTL6,SEPT7,CDH8,LOC730101,LARGE1,NOG,NUMBL,CHN2,NDST3,EPS15L1,KIAA1549L,TPP1,IGLON5,IQCK,COL11A2,SLC4A8,SLC35F1,CDC42BPB,C2CD2,RBM39,CRY2,ANKRD44,GDA,CSF1,RGS6,LRRC3B,CSNK1E,RASGEF1C,SLITRK5,CTNND1,NRSN1,ZSCAN23,FGFR1OP2,GAPVD1,SNPH,TM9SF4,RIMS3,ZEB2,MFAP3L,TMEM130,FBXO25,GUCD1,RHOBTB1,SRGAP3,TMCC2,SEC16A,DLX1,DMD,DMPK,USP3,CD99L2,SLC29A4,DNM2,DPYSL2,DYRK1A,EBF1,ANKRD46,SYT15,TMTC1,CELSR3,PHF20L1,EGFR,EIF4G1,ELAVL3,TNK2,ELN,C3orf18,EFS,ZNF549,SPEG,VPS26C,CEND1,SIRPB1,MRVI1,HSPA12B,ABCA8,ZNF461,TAOK3,ZMYND10,FKTN,ZNF589,GORAB,SLC9B2,POLK,SUCO,FOXF2,AGAP2,SYNCRIP,SEMA6C,EVL,COQ5,ZBED3,SPECC1,ARFGAP2,CELF1,TBR1,ZMYND11,B4GALNT1,ARPP21,GAP43,ATP8A2,SRCAP,GPR162,GGT7,GHR,PPARGC1A,BRD8,CRCP,MSL3,KDM2B,INSM2,DCLK2,GNAO1,GP1BB,GPD1,TMEM121B,SPACA9,NR3C1,RNF165,FAM222A,HPS5,NXPH3,MAN1B1,ATXN2L,SYNPO,AGBL5,HNF4G,HSPA1L,SMAP1,MYLK2,BRINP3,ZNF385B,LRRTM1,ITGAM,KCNJ3,KCNJ4,KCNK1,L1CAM,PAXBP1,MAT2A,MBD1,PPM1L,COL28A1,JAKMIP3,BLOC1S2,PTOV1,MT3,N6AMT1,MYO7A,NCAM1,NCAM2,NFE2L2,NPY,NTRK2,NUCB2,OCRL,OXTR,PAK3,PBX1,PDGFRA,BEST3,ZNF655,FAM218A,A2ML1,ST8SIA5,SLC25A23,ZNF426,MTRF1L,PNMA3,MAPKAP1,SCHIP1,POLR2F,KANSL1,VSTM2L,PKIA,PRKCG,MAPK3,KLK6,PSD,BCAS3,VPS13C,SIDT1,GON4L,MDGA2,QRICH1,UHRF1BP1,NCR3LG1,PTPRN,NKAIN1,CCDC40,ZDHHC14,MSANTD2,TRIM68,PRRT2,RGS12,ALG9,RAVER2,NEK11,PRR5L,TCP11L1,CNTNAP3,NCBP3,RMI1,AMER2,SCN2B,SCN7A,SCN8A,ASIC4,GALNT10,SGK1,KIF16B,BTBD3,FAM214B,SLC6A1,LRRC55,SLC6A7,SLC8A1,SLC11A1,SHANK2,ELMO2,SORCS3,INAVA,MAPKBP1,MBD5,DOP1A,SOX10,SP4,CAND2,SPTB,IQSEC2,NFASC,CLASP2,ITPRID2,NKAIN2,DIP2A,ADHFE1,PHLDB1,GANAB,NSFL1C,ADAMTS17,ARC,SYT5,CAMSAP2,VWA3A,EHBP1,CUX2,TRIM2,CLASP1,SZT2,AZIN2,SYNE1,PCDHB9,PCDHB3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,SLC44A1,MTMR14,TK2,ERCC6L2,TMOD1,RIMBP2,CABIN1,TPM2,TPM3,TPM4,RGMB,PDSS1,ZMYND8,DCBLD1,TSC1,TTTY15,LRTM2,UBTF,PLPPR2,CCDC136,VLDLR,CLDND1,ZBTB14,LYPD6,POLR3H,AMZ1,EML6,ZNF213,MFF,PRDM2,PARP6,LINC02210,STOX2,NAV2,SNX27,FIP1L1,FAM47E,WIPF2,ST7,CAMK1G,TTC7A" MicroRNA hsa-miR-523*:mirSVR_lowEffct hsa-miR-523*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-522*:mirSVR_lowEffct hsa-miR-522*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-519c-5p:mirSVR_lowEffct hsa-miR-519c-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-519b-5p:mirSVR_lowEffct hsa-miR-519b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-518e*:mirSVR_lowEffct hsa-miR-518e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-519a*:mirSVR_lowEffct hsa-miR-519a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-126 2.22E-122 4.21E-125 3.88E-124 348 1555 "ASIC1,NCKAP5,SYS1,CSMD3,ADCY2,ADCY6,CCDC85A,GALNT13,ADD1,BEND6,NLGN4X,INTS2,ZNF578,LRRC7,ALAD,ALCAM,FAM135A,LRCH2,ANXA7,APBA2,APC,EPB41L5,VAT1L,TNRC6C,AQP4,MIER1,SEMA4G,PRX,TMEFF1,LINC00173,ASCL1,PDE8B,CCDC74A,TMEM108,SLC4A4,ATP1B3,STX16,ATP2A2,NOL4,TTLL9,BACH1,BCL2L2,BTK,BTRC,CACNA1B,CACNA1D,CALB2,PTBP2,SYT6,RUNX1T1,NFS1,CBR1,CCNH,MTMR7,ARHGEF1,CDH8,DCLK1,CHN2,SYNPR,JAM2,COG1,ARHGEF6,SLC4A8,AHCTF1,CLOCK,CREM,RBM39,RNF14,CS,SUSD5,KIAA0040,RIMS2,FAM131B,HDAC9,PHYHIP,SPOCK2,ZEB2,HEPH,C2CD2L,BLOC1S6,ZC3H11A,DDX46,ALKBH8,PLPPR4,NTM,G3BP2,WDR20,ARNT2,RAB39B,DNM1,USP3,CDON,DPH1,CASP8AP2,DPP6,ABCC9,E2F5,EBF1,FRY,FSD1L,YAF2,SH3GLB1,KMT5B,ABI2,EIF4G2,CALCRL,PAN3,RAB9B,EPS8,SPEG,CDHR1,ABCA8,TUBB4A,ATP8A1,CEP78,FHL1,POLK,MEX3B,HPCAL4,EVL,PSD2,SORBS1,PDLIM5,STAMBP,ZNF605,PNMA2,OGA,ZMAT1,MEGF10,GABRA3,ZNF44,TRAF3IP2,CAB39,GAD2,GALC,IQGAP2,TMEM8B,SIGLEC8,NEU3,TUBGCP4,SULT1C4,PPARGC1A,LYVE1,BRD8,GK,TCERG1,HPGDS,PCDH11X,INSM2,GNAL,PRUNE2,FUT10,CCDC184,GPR17,MCHR1,NUDT21,EML4,TMEM121B,PCLO,GRIA2,RFFL,GRM7,CLASRP,FAM19A2,ZBTB49,PSIP1,CELF3,ARHGAP19,HNF4G,HNMT,SMAP1,HTR2A,ATCAY,EID2B,SOWAHA,IGF1,TJAP1,DISP2,SCIN,IL6R,ITGAV,SLC35G1,KCNC1,KTN1,LAMP2,LIG4,LIMS1,ARHGAP12,MAT2A,SHC3,MEIS1,MN1,DBNL,SESN3,N6AMT1,C10orf105,ZC3H12B,NDUFA5,CCDC13,NFYA,CNOT4,NOVA1,DNHD1,NTRK2,PRTG,PDGFRA,NALCN,A2ML1,PLIN1,PLP1,PDZRN4,FAT3,SH3KBP1,PPP2R5C,PRKAB2,GRAMD1C,PROX1,SNRK,QRICH1,PTHLH,PTPRN,STRC,RASGRF1,ZMAT4,REV3L,RGS4,NUDT11,CCDC82,TMLHE,ARMC5,PCMTD2,SNX22,NEK11,ATP8B4,SGSM1,PRR5L,ADAL,CLIP1,ZNF331,AMER2,PRCD,SCP2,ELMOD1,SEC14L1,CASC3,ASRGL1,NLGN4Y,PPP1R9A,FBXO11,ST3GAL3,ANKRD6,SLC1A3,KANSL3,LRRC55,SLC6A11,RAB3GAP1,SHANK2,BTBD7,SLIT1,CDK5RAP2,SMARCD3,RCOR3,INAVA,LIMCH1,RIMS1,MAPKBP1,SNRPN,MYO16,UNC80,SON,SOX5,CLUAP1,EMC1,PEG10,ATP10B,SSTR1,ZC4H2,NXT2,NEK4,KANK1,PRRC2C,VPS13A,COBL,ANKRD28,ATP11A,KAZN,MTCL1,CAMSAP2,ADGRL3,TBX15,VWC2,TRIM2,TCF12,PCDHGB7,DOCK9,ARHGEF12,HIF3A,RNF216P1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,AKTIP,TJP1,RIMBP2,TRIO,STXBP4,DCBLD1,RUSC1,ANKRD20A2,TTPA,ZKSCAN5,TUBB1,CADM1,SLAIN1,USP1,BCL2L13,VLDLR,GUSBP1,ZIC1,ZIC3,ZNF711,ZNF23,TRIM9,GPR158-AS1,CRB2,REEP1,ANKS1B,PLPPR5,CA10,SLC30A4,EMSY,ADAMTS9,SEMA3B,PCDH15,LINC00632,PCBP4,PDSS2,DNAH10,DOCK8,UBE3B,PAK5,PHTF2,MSRB3,SSPN,LAS1L,JPH3" MicroRNA hsa-miR-103-2*:mirSVR_highEffct hsa-miR-103-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.04E-126 2.83E-122 5.38E-125 4.95E-124 334 1437 "KCNH8,ASIC2,ACLY,ADAR,KLHL32,TMCC3,SLC12A5,PLEKHH1,KIAA1211,AP2A2,WDR35,CC2D2A,ALCAM,ABCD2,PCDH10,UNC79,ANK2,ANK3,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,ALS2,API5,LGR5,TMEM263,ARHGAP5,ARNTL,RGS20,MARK4,DDX3Y,TMEM108,NOL4,ADAM23,BACH1,ADGRB3,CFLAR,SYNJ2,NAE1,CACNA1G,CA4,CACNB4,VXN,ISPD,RUNX1T1,CERS5,CCNT1,LRBA,ARHGEF2,CDH8,CDH10,LGI1,LOC730101,MAGI1,CLGN,NOG,CHGB,NDST3,IGFBP7-AS1,NRXN1,CLTA,NGEF,TJP2,ABCG2,DNAJB5,AKAP7,FAM149A,SLC4A8,BAG4,MYRIP,CHD1L,CLOCK,CREM,SH2B1,AKAP12,HAPLN1,GDA,FEZ2,OSBPL3,PLCH2,VAC14-AS1,PDE4DIP,DZIP3,UBXN2A,PHF14,GREB1,CTNND2,RIMS2,CYBB,BOC,FRMPD4,RIMS3,DGKB,ARMCX4,ZBTB24,HEPH,HP1BP3,CEP170,MAGI2,DDX46,SPOCK3,G3BP2,RABGAP1L,WDR20,DLX1,EXOG,DTNA,ECM2,DYRK1A,ABCC5,ABCC9,GOLT1B,HIPK3,RASGRP1,FSD1L,RBM12,MBNL2,KMT5B,TENM1,TMEM35A,EPB41,LRRC17,KCNMB2,EPS8,CDKL3,F5,CACNG2,SCML2,EFEMP1,CEP78,FER,FGF1,OLFM1,FGFR3,FHL1,NBEA,SORBS1,SMC2,HVCN1,ZNF605,DACH2,SARAF,AP4B1,ABLIM2,ZNF512,STAG2,MEGF10,CAB39,ZMYND11,SALL3,ERAP1,MYOZ2,SESN1,GHR,GK,COPS8,GLS,MSL3,ZNF638,GNAL,FERMT2,GPD2,GRIA2,PLCD4,GRIN1,NR3C1,GRM7,HPS5,ZHX1,AGBL5,ZNF491,USP51,NEGR1,SHISA6,SMAP1,C5orf24,SCIN,IL6ST,TUBB2B,LRRTM3,KCNA1,KCNC1,KCNC2,KCNK1,KCNK2,KIFC3,KLC1,KTN1,NCOA7,LYPLAL1,TM6SF1,MEF2C,MID1,MITF,AFDN,XRRA1,WDR49,MOBP,GIT1,LAYN,MYO7A,RTL5,NAP1L2,NCAM2,NELL2,NF1,SMIM11A,NUCB2,NUMA1,OGG1,OXTR,GPR137C,PAK3,PBX1,PCSK1,PDE3A,GPR85,GNG2,PFKFB3,TMIE,SNX10,RETREG1,ANKRD16,SCHIP1,DRAM2,PPP2R5C,KANSL1,CNNM2,SYTL2,PTPRE,FAM120C,RAP1GDS1,ZNF493,OXR1,VEPH1,ZDHHC14,RFX4,RIT2,PBRM1,ZFHX4,LGI2,CARF,ROBO1,ROBO2,NEK11,ARMH4,ACER3,TCP11L1,LGR4,ATAT1,RYR3,TRAPPC13,TMEM156,SEMA6D,SCN2A,LINC00461,SGK1,ITSN1,SH3GL2,SH3GL3,ARX,CPEB3,MAGI3,SYBU,CTXN2,PPP4R3A,SLC8A1,CCDC88A,SLC12A2,SLC20A2,ATF7IP,SLCO1A2,RCOR3,ANKRD36,SNRPN,UNC80,SON,PDZD2,DOK5,TSPYL2,SPART,CLASP2,LARP4,NKAIN2,RGL1,FGD4,SUPT5H,PLCB1,KAZN,TBCEL,ANO4,RPGRIP1L,PCDHB7,DICER1,SIRT1,SLC44A1,ZFP91,ERCC6L2,RBFOX2,SEZ6L,C9orf85,SYNPO2,AMACR,SSBP2,ZKSCAN5,USP1,ZNF709,BCL2L13,P2RY12,ZNF711,MICU3,AGMO,PLPPR5,SMARCAD1,UPF3A,PRTFDC1,DNALI1,STMN4,VPS35L,PCDH15,FIP1L1,SLC17A6,FAM13C,MARCH8,CASC15,TRAM2-AS1,ZNF248,KLHDC1,FXR1,FRMD6,SLC4A10,GAN,FAM198A" MicroRNA hsa-miR-502-3p:mirSVR_lowEffct hsa-miR-502-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.62E-126 3.72E-122 7.05E-125 6.49E-124 318 1306 "ASPHD1,NCKAP5,XKR4,FMNL2,ADCY2,RNF157,ADD3,ERMN,NLGN4X,MTUS1,GPR158,KLHL13,TXNDC16,TAOK1,ALCAM,PCDH10,KCNT1,AMPD2,AMT,DPP10,USP28,PPFIA2,APP,SLC7A14,SEMA4G,ZBTB10,ATP1A2,ATP2A2,DPY19L3,TTLL9,BCHE,C5,MYRF,CACNA1B,VSTM2A,MTMR7,CD38,DCLK1,DLGAP1,PPT2,CLTC,QKI,TMEM184B,MAP4K4,BTF3L4,LETMD1,AKAP5,TOGARAM2,FAM171B,SEC31B,SEC24C,LRIG1,ARHGEF10,MICAL2,OSBPL3,SIPA1L1,CHD5,CST3,PLXNA4,FAM169A,KIAA0040,ERC2,CTNND2,RIMS2,SEC14L5,NOS1AP,KIAA0408,HDAC9,GAPVD1,LONRF1,KCTD8,PHYHIP,DGKB,TOMM20,GIT2,DCC,CNIH3,KLHL3,SRGAP3,ARNT2,DMD,DYNC1I1,DMTF1,DTNA,ABCC5,ATL1,HIPK3,SEMA3D,EGFR,OLIG2,LRRC17,EPHA5,CEP85L,ZNF549,ADGRV1,FAM198B,ZIC4,EFEMP1,TOMM40L,MED12L,FGF13,FGFR1,FLYWCH1,UFM1,TPK1,ATP2C1,NSG2,DKK3,GABRG2,GAD1,ZMYND11,B4GALNT1,JPH4,GALR1,C15orf41,ATP8A2,ALDH1L1,GCNT2,GGTA1P,PPARGC1A,TCERG1,RAB30,GPM6A,GPM6B,GPR12,GRIA1,DIDO1,PLPP7,SERP2,ATE1,GRM5,FAM19A2,RNFT2,PTGDR2,KLF12,GABARAPL2,EID2B,USP54,LRRTM3,KCNA1,OLFM3,KCNJ3,KCNK3,KIF2A,KLRC2,LAMA2,ZFYVE27,MARK1,LYPLAL1,MBNL1,LRP1B,MID1,MOBP,COL28A1,N6AMT1,RSPO2,MXI1,MYO7A,ZNF862,TCEAL5,NEFH,NELL2,NFIA,NFE2L2,ALDH1L2,SMIM11A,TBC1D25,OCRL,P2RY1,PAX6,PBX1,PCSK5,PDE4D,PENK,PFKFB2,PFKFB3,DUSP26,ANLN,ZNF655,XRN1,ST8SIA5,PLP1,MTRF1L,ING3,MED1,PPM1B,RAB39A,GDPD1,SNRK,CNTLN,MTMR10,TMEM260,PTPRO,FAM120C,ZNF844,TMEM255A,CCDC40,ZNF793,REV3L,RGS3,ARHGEF10L,SLC25A36,RIC8B,RPRD1A,CYB561D1,RORB,ELP2,RPE,FBXW7,ADAL,MAP6D1,LGR4,PAQR6,KCNIP3,RTN1,AP1AR,RMI1,SCN2B,SCN3A,LINC00461,SCP2,ASIC4,SOX6,GALNT10,SUPT20H,ITSN1,MAGI3,SYBU,NLGN1,PAAF1,CLSTN1,FAM81A,PPP4R3A,ZNF430,RAB3GAP1,SLC9A5,SLC20A2,ATF7IP,TET1,SMARCC2,SMARCD3,SMARCE1,RIMS1,SNAP25,SNRPN,FAM126B,SON,PDZD2,WDTC1,MYT1L,SOX2,NFASC,TAB2,ATP10B,TROVE2,SSTR1,LARP4,NXT2,ELOVL4,CEP68,DIP2A,KANK1,NECAB1,ZC3H4,SYNE2,VPS13A,ANKRD28,ANKRD12,MTCL1,CAMTA1,CAMSAP2,WWC1,ANO4,WDR7,AZIN2,DOCK9,TMEM151B,RALYL,TEK,C18orf54,AP4E1,TGFBR3,TJP1,ACTR6,ERCC6L2,CSMD1,NPL,DOK6,AMACR,HSPBP1,PRR18,SLC35A4,FLRT1,MGAT5B,RICTOR,XPO1,SF1,PCDH20,ZIC1,ZIC3,ZNF711,ZNF708,ZNF24,ZBTB16,TMEM198,ZFAND5,CADM2,PRDM8,ADAMTS9,TMEM178A,LINC00632,HRASLS,DOCK8,PHTF2,ADAMTSL3,NHSL1,IFT88,ST8SIA2" MicroRNA hsa-miR-19b-1*:mirSVR_highEffct hsa-miR-19b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.81E-126 3.82E-122 7.23E-125 6.66E-124 317 1298 "ARID1A,CSMD3,FMNL2,SORCS1,KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,ANK3,USP28,GPAM,VAT1L,API5,APP,SHTN1,PPP4R4,SPTBN4,NUMB,EIF4G3,B3GALT2,NOL4,BACH1,BCL7A,LINC00906,MTMR2,SGCE,OSGIN2,IL33,CACNA1B,CACNA2D1,CALM1,KALRN,PTBP2,CAMK2D,CAMK2G,VSTM2A,CAST,CDH8,LRRFIP1,NOG,CFL2,CBARP,CHGA,SOCS6,CHM,CASC2,JAM2,NRXN3,PPT2,CLCN4,NRXN1,FBXO7,FAM189A2,C4orf33,NIPBL,CNN3,ARMC8,SUMF2,RCHY1,MYRIP,IGDCC3,MFSD4A,CP,SLC35F1,FAM171B,CLOCK,FEZ2,MICAL2,CSNK1G3,SUSD5,PLCH2,PLXNA4,PHF14,CTH,CTNND1,ST18,USP6NL,ARHGAP32,FRMPD4,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,CEP170,MAGI2,RHOBTB1,AK5,FAM107B,NR1D2,CPEB2,ABI1,DTNA,EDN1,EDN3,EDNRB,RASGRP1,PHF20L1,EGFR,EIF4G2,ELAVL4,EMX2,LRRC17,STX2,CEP85L,CDKL3,RTN3,TLR7,CACNG2,TMEM132C,TAOK3,DLC1,TOMM40L,FDFT1,SUCO,CAP2,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,NPTN,ATP2C1,CELF1,PHYHIPL,MEGF10,CHL1,CAB39,GAD2,HBS1L,ATP8A2,GATM,NEU3,WASHC2A,AHDC1,ADAM28,TXNL4A,GLI2,GLRB,ZNF638,GNAO1,FERMT2,GRB10,GRIK2,PTPN5,SOX21,HAS2,FRMD3,ARHGAP36,HNF4G,NEGR1,SHISA6,SMAP1,LIX1,ZNF678,KCND2,KCNK2,KCNN3,STXBP5,TTYH2,LAMA2,PAXBP1,VWA5A,ASPRV1,PIK3AP1,MARK1,MATN2,SYT9,EFHB,KCTD6,MIA2,PPM1L,MITF,MOG,ERICH3,MYO9A,NAP1L1,NAP1L2,SFR1,NF1,NFE2L2,SMIM11A,OGG1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,PDE4D,OLA1,NLGN3,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,SLC36A4,POU3F2,CCDC144B,MAPK10,HYDIN,SIDT1,ELOVL2,PTK2,PTN,STK32A,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RNF220,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,RPE65,SPIN3,MCMBP,ACER3,ABCA11P,HSD11B1L,RTN1,FAM182A,SATB1,ATXN7,SCN7A,FNIP1,KIF21A,SH3GL2,CPEB3,CTXN2,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,PALLD,MYO16,UNC80,SOX5,KDM3A,SP4,ZC3H13,NPAS3,ZC4H2,NXT2,RGL1,SYT11,VPS13A,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,WASHC4,PCDHB9,OBSL1,PUM2,CRB1,GZF1,NR2E1,TMPO,C9orf85,TPM4,SYNPO2,TRO,TRPC1,ANKRD20A2,TUB,TMEFF2,TUBB1,RPL7L1,FAM155A,UGT8,P2RY12,NSD2,GUSBP1,XPO1,XRCC4,CFAP298,ZNF28,KCNT2,ZNF540,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,SPIRE1,CA10,PRDM2,CSDE1,STOX2,TMEM178A,NAV3,SLC17A6,PDSS2,FZD3,SSPN,KLHDC1,SLC4A10" MicroRNA hsa-miR-1228:mirSVR_lowEffct hsa-miR-1228:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.54E-126 4.23E-122 7.95E-125 7.32E-124 355 1619 "DPF1,RALGAPA1,ABAT,CSMD2,KLHL32,GRAMD1B,RNF150,ZNF608,NME5,SMIM17,AMPH,FGD2,MAP4K3,ANXA7,GPAM,FAM131A,TMEFF1,SPTBN4,ZFYVE28,ARRB1,LINC00173,CDK13,STK33,DDX3Y,CHID1,ATM,EIF4G3,SLC2A11,N4BP2L1,RIPK1,ADAM15,ADGRB2,BMPR1B,SYNJ2,CA8,CAST,RUNX1T1,PRC1,ZNF501,CLDN10,USP6,CBFA2T2,C1orf52,ZMYM4,TIGD7,GPR37L1,SRSF11,CHM,EPS15L1,CPNE6,PPT2,CLU,STOML1,CLTA,CLTB,CLTC,TJP2,ABCG2,SULT4A1,MAP4K4,CNR1,AKAP7,COL4A5,LETMD1,CLOCK,RBM39,CRY2,ANKRD44,CSF1,VAC14-AS1,PLXNA4,SLITRK5,NRSN1,PPP6R2,DCAF4,RUBCN,NOS1AP,MYADM,FGFR1OP2,TOX,ZNF337,LONRF1,KIAA0586,ARMCX4,DNAJC6,ZEB2,MYEF2,HP1BP3,GUCD1,POM121,SMG7,SV2B,SRGAP3,GRIN3A,RAB39B,RPS6KL1,DPP6,ACOT8,DTNA,MAMLD1,DNM1L,ABCC9,E2F5,RBM12,FAM13A,APH1A,MRO,EIF4G2,MTSS1L,STX2,VPS26C,MRVI1,CHST15,FDFT1,OLFM1,POLR1B,CAMSAP1,POLK,FOXM1,SGIP1,C2orf88,WDR83,TMEM107,SMC2,NPTN,ZNF605,CGREF1,MPP6,ABLIM2,NEURL4,GABBR1,GABRB1,AHCYL1,BRPF3,GALC,ZNF234,TMEM8B,KIAA1841,MYOZ2,TUBGCP4,SULT1C4,USP19,MALT1,RUNDC3A,ZNF276,COPS8,TNRC6A,MSL3,PCDH11X,ADGRA3,PRUNE2,GRB10,GRIA2,GRID1,NR3C1,GRM2,GRM7,FAM107A,RNFT2,GPR45,ZNF491,TLX1,OPALIN,DHX35,SMAP1,MSL1,ZNF546,ZIC5,TJAP1,IL6R,TUBB2B,ITGA7,KCNJ9,KCNJ11,LINC00634,LAMP2,NCOA7,NAT8L,ZFYVE27,MAP2,SHC3,MEIS1,MEIS2,MID1,MN1,JAKMIP3,MT3,MYO6,MYO7A,RTL5,NAP1L3,ZC3H12B,NDUFA5,VWA2,NRCAM,NUMA1,IGSF11,OPHN1,P2RX7,PCDHGC3,PCSK2,PDCD2,PDE2A,PIRT,NALCN,CAMKV,NLE1,FTO,ZNF426,PURG,POU3F2,PPARA,TATDN3,PPP2R5E,CEP41,MAPK10,MASP1,BCAS3,GON4L,CNTLN,UHRF1BP1,PTK2,PTPRB,PTPRD,PTPRG,ACSM5,RAD52,OXR1,ZDHHC14,PRRT2,RFX3,UBR7,KCTD17,RNH1,CCDC102B,SNX22,MCMBP,SGSM1,ACER3,TCP11L1,PTGR2,RPS20,PAQR6,ZNF568,ZNF331,DGLUCY,SEMA6D,SATB1,PEAR1,ASAP3,CHD9,DZIP1,NUBPL,ZNF365,SLC1A6,DHX30,KANSL3,PKNOX2,SLC6A8,KBTBD4,SLC15A2,ELMO2,SLC20A2,DMRTC1,CDK5RAP2,IGSF9B,LIMCH1,SNCB,SNCA,CMTR2,SNRPN,FAM219A,WDTC1,MYT1L,SOX3,SOX5,CLUAP1,IZUMO4,SPP1,ERC1,ZC3H13,NPAS3,NFASC,CAMTA2,POGZ,SSTR1,LARP4,MAPK8IP3,MPRIP,KANK1,SULF2,ZC3H4,SYNE2,VPS13A,DNAJC9,SYPL1,SYT1,C12orf76,UNC5D,FBXW11,KLHL4,ANO4,TBX15,DMXL2,ZEB1,TPCN2,TCF12,WDR7,USP32P1,CYB561A3,FAM200B,SIRT1,ZFPM2,CRB1,ARL10,TIAM1,TIE1,HEY1,DDHD1,KCTD2,KAT6B,TPD52L2,C9orf85,SMUG1,STXBP4,DCBLD1,CLHC1,CLEC2L,LINC00689,PITPNB,LAT2,NSD2,RICTOR,ELFN1,FMN2,ZBTB38,POLR3H,ANKS1B,PCBP1-AS1,MEIS3,UPF3A,DHX33,LINC02210,PRDM10,LMAN2L,HPS4,PCDH15,FAM47E,WIPF2,RGS7BP,CAMK1G,MSRB3,IFT88,LAS1L,FAM198A" MicroRNA hsa-miR-200c-3p:TargetScan hsa-miR-200c-3p TargetScan 7.54E-126 4.24E-122 7.95E-125 7.32E-124 261 874 "ABAT,CSMD3,ADCY2,ADD3,NLGN4X,GPR158,HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,ANK3,MAP4K3,PHF12,PPFIA1,APAF1,CACHD1,CASK,ARHGDIA,CDK13,NUMB,DDX3Y,ATP2A2,DCAF5,NRP2,GPR146,KSR1,FUBP1,JAZF1,MMD2,FOXK1,CACNA2D1,CAMK2D,RUNX1T1,ARHGEF1,CDC27,DLGAP2,NOG,CFL2,CHN2,KMT2C,NGEF,FAM19A5,DNAJB5,QKI,MAP4K4,NIPBL,CNN3,CNTFR,BTF3L4,COL9A3,GAL3ST1,SEC31B,CLOCK,CREB5,NCOR2,LRIG1,FEZ2,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,CTNND2,RIMS2,DOCK4,HDAC4,MATR3,RIMS3,KIAA0087,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,ABCC9,HIPK3,ABI2,EGR3,PLXNC1,GOLGA7,ELAVL2,ELAVL4,PAN3,MTSS1L,EPS8,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXG1,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GAB1,GABRB3,CAB39,GAD2,GBX2,COPS8,FERMT2,GPM6A,CECR2,RAPGEF1,PARD3B,NR3C1,PSIP1,RASSF8,HAS2,FRMD5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HNRNPK,NEGR1,AGFG1,NKD1,IL6ST,SCRT2,LRRTM3,CDH20,KCNB1,KCND2,KCND3,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,JAKMIP3,MXI1,MYCN,MYO9A,MYT1,NCAM1,NFIA,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,HCN1,PAK3,PCDH8,PCSK5,PCSK2,PDPK1,GPR173,ANLN,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,FAT3,NXPH1,POU6F1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,PROX1,RELN,CNNM2,PTCH1,PTHLH,PTPN13,CEP97,OXR1,ARID4A,RBBP8,FIGN,SEC61A2,RPRD1A,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,ATXN1,SCN2A,SCN8A,ITSN1,PPP1R9A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,SCN3B,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,C11orf87,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,GSE1,ANKRD28,CAMSAP2,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,FBXL16,NACC2,CBX5,ASXL3,LRRC8A,RBFOX2,NR2C2,ANO5,CADM1,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,CERS6,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-429:TargetScan hsa-miR-429 TargetScan 7.54E-126 4.24E-122 7.95E-125 7.32E-124 261 874 "ABAT,CSMD3,ADCY2,ADD3,NLGN4X,GPR158,HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,ANK3,MAP4K3,PHF12,PPFIA1,APAF1,CACHD1,CASK,ARHGDIA,CDK13,NUMB,DDX3Y,ATP2A2,DCAF5,NRP2,GPR146,KSR1,FUBP1,JAZF1,MMD2,FOXK1,CACNA2D1,CAMK2D,RUNX1T1,ARHGEF1,CDC27,DLGAP2,NOG,CFL2,CHN2,KMT2C,NGEF,FAM19A5,DNAJB5,QKI,MAP4K4,NIPBL,CNN3,CNTFR,BTF3L4,COL9A3,GAL3ST1,SEC31B,CLOCK,CREB5,NCOR2,LRIG1,FEZ2,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,CTNND2,RIMS2,DOCK4,HDAC4,MATR3,RIMS3,KIAA0087,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,ABCC9,HIPK3,ABI2,EGR3,PLXNC1,GOLGA7,ELAVL2,ELAVL4,PAN3,MTSS1L,EPS8,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXG1,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GAB1,GABRB3,CAB39,GAD2,GBX2,COPS8,FERMT2,GPM6A,CECR2,RAPGEF1,PARD3B,NR3C1,PSIP1,RASSF8,HAS2,FRMD5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HNRNPK,NEGR1,AGFG1,NKD1,IL6ST,SCRT2,LRRTM3,CDH20,KCNB1,KCND2,KCND3,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,JAKMIP3,MXI1,MYCN,MYO9A,MYT1,NCAM1,NFIA,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,HCN1,PAK3,PCDH8,PCSK5,PCSK2,PDPK1,GPR173,ANLN,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,FAT3,NXPH1,POU6F1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,PROX1,RELN,CNNM2,PTCH1,PTHLH,PTPN13,CEP97,OXR1,ARID4A,RBBP8,FIGN,SEC61A2,RPRD1A,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,ATXN1,SCN2A,SCN8A,ITSN1,PPP1R9A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,SCN3B,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,C11orf87,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,GSE1,ANKRD28,CAMSAP2,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,FBXL16,NACC2,CBX5,ASXL3,LRRC8A,RBFOX2,NR2C2,ANO5,CADM1,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,CERS6,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-200b-3p:TargetScan hsa-miR-200b-3p TargetScan 7.54E-126 4.24E-122 7.95E-125 7.32E-124 261 874 "ABAT,CSMD3,ADCY2,ADD3,NLGN4X,GPR158,HECW2,CASKIN1,PCDH19,KCTD16,ARHGAP20,ANK3,MAP4K3,PHF12,PPFIA1,APAF1,CACHD1,CASK,ARHGDIA,CDK13,NUMB,DDX3Y,ATP2A2,DCAF5,NRP2,GPR146,KSR1,FUBP1,JAZF1,MMD2,FOXK1,CACNA2D1,CAMK2D,RUNX1T1,ARHGEF1,CDC27,DLGAP2,NOG,CFL2,CHN2,KMT2C,NGEF,FAM19A5,DNAJB5,QKI,MAP4K4,NIPBL,CNN3,CNTFR,BTF3L4,COL9A3,GAL3ST1,SEC31B,CLOCK,CREB5,NCOR2,LRIG1,FEZ2,CSNK1G3,PHACTR3,PLXNA4,PITPNM3,KIAA0040,PLCXD3,CTNND2,RIMS2,DOCK4,HDAC4,MATR3,RIMS3,KIAA0087,GIT2,JAKMIP2,RUSC2,KLHL3,FAM107B,CHRDL1,DMD,NYAP1,DTNA,ABCC9,HIPK3,ABI2,EGR3,PLXNC1,GOLGA7,ELAVL2,ELAVL4,PAN3,MTSS1L,EPS8,ERBB4,CEP85L,KATNAL1,DLC1,FGF12,AMOTL2,POLK,MEX3B,FOXG1,FOXF2,FLT1,JKAMP,FAM49B,CELF1,DOT1L,FYN,GAB1,GABRB3,CAB39,GAD2,GBX2,COPS8,FERMT2,GPM6A,CECR2,RAPGEF1,PARD3B,NR3C1,PSIP1,RASSF8,HAS2,FRMD5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HNRNPK,NEGR1,AGFG1,NKD1,IL6ST,SCRT2,LRRTM3,CDH20,KCNB1,KCND2,KCND3,NCOA7,MAP2,MBNL1,LRP1B,AFF1,MMP16,JAKMIP3,MXI1,MYCN,MYO9A,MYT1,NCAM1,NFIA,NFYA,CNOT4,NOVA1,NOVA2,NPTX1,HCN1,PAK3,PCDH8,PCSK5,PCSK2,PDPK1,GPR173,ANLN,PKD1,KCTD15,PLCL1,PSAT1,SCHIP1,SDK2,FAT3,NXPH1,POU6F1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,PRKACB,CEP41,PKIA,DIRAS2,PROX1,RELN,CNNM2,PTCH1,PTHLH,PTPN13,CEP97,OXR1,ARID4A,RBBP8,FIGN,SEC61A2,RPRD1A,CCDC82,ROBO2,RPE,FBXW7,RPS6KA2,CLIP1,SBF1,CSRNP3,ATXN1,SCN2A,SCN8A,ITSN1,PPP1R9A,AMBRA1,CHD9,R3HDM2,DZIP1,FAM81A,NAPB,ATF7IP,MBD5,KIF13A,SCN3B,FAM219A,BDP1,ERC1,ARHGAP26,IQSEC2,CDK19,RBM26,NFASC,C11orf87,CLASP2,MPRIP,RGL1,PHLDB1,KANK1,GSE1,ANKRD28,CAMSAP2,FBXW11,ATMIN,CLASP1,PUM2,GPRIN3,FBXL16,NACC2,CBX5,ASXL3,LRRC8A,RBFOX2,NR2C2,ANO5,CADM1,RBFOX3,CLIP2,KCNK12,REEP1,EVI5,MARCH8,PHTF2,CERS6,RSPRY1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-187*:mirSVR_lowEffct hsa-miR-187*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.21E-126 5.17E-122 9.69E-125 8.93E-124 332 1423 "ACADM,ARID1A,ADCY2,KLRC4,ADD1,ESYT2,PTCHD1,LRFN2,SNX32,OSBPL8,TXNDC16,SPARCL1,USP35,ALCAM,SRPX,UNC79,FAM135A,GPRASP2,ZNF687,CDC42BPA,SHROOM2,AQP4,CASK,STK33,NCOA1,ATP1B3,ATP2B1,DPY19L3,BCHE,ARHGEF7,JAZF1,CALM1,KALRN,PTBP2,CH25H,ISPD,SPAG9,MAP7,TIGD7,CLGN,CHM,CHN2,PLEKHB1,KMT2C,CPNE6,RAB28,CLU,FAM19A5,QKI,NIPBL,TMEM155,CNTN1,SLC4A8,ZNF521,SEC31B,ANKRD44,ARHGEF10,SIPA1L1,APPL1,UBXN2A,GREB1,ARHGEF4,RIMS2,ARHGAP32,HDAC4,PHF19,KIAA0586,DNAL1,DBN1,SPATA2,YTHDC1,ZBTB24,MYEF2,KIAA0319,ZC3H11A,DDX46,SNAP91,G3BP2,GRIN3A,RAB39B,DMD,CD99L2,CPEB2,DMTF1,DYRK1A,ABCC5,DNM1L,SGK2,RASGRP1,FRY,APH1A,TMEM132E,RASA4,GOLGA7,EIF4G2,ELAVL2,EPHA5,CEP85L,ZNF549,RCSD1,EZH1,CLVS1,ATP8A1,FOXG1,PCYOX1,FLT1,NOP56,TMEM107,SMC2,UFM1,STAMBP,CAMKK2,ATP6V1H,ZNF605,CGREF1,STAU2,KBTBD12,STAG2,GABRA1,CAB39,GAD1,GAD2,ARPP21,DISC1,MYOZ2,SULT1C4,MSTN,GDF9,PPARGC1A,COPS8,SPIN1,GLS,TNRC6A,GLUL,LUZP2,FERMT2,GPM6B,GPR37,RFFL,NR3C1,GRM1,GRM2,GRM5,KIF3A,FAM107A,WIF1,PADI2,ELOVL5,HNF4G,ZDHHC15,NEGR1,AGFG1,SHISA6,LRRCC1,IL6R,SLC6A17,OLFM3,CLVS2,KCNK1,KCNK3,KIT,IPO5,STXBP5,STMN1,SYTL4,NCOA7,MBP,IL17D,CHIC1,TM6SF1,KCTD6,MIA2,AFDN,GIT1,N6AMT1,MXI1,LYRM9,HNRNPM,NAP1L2,ZC3H12B,NEK1,NEUROD2,SLCO1C1,ALDH1L2,NOVA1,NPR2,OCRL,GLIPR1L2,PCSK1,PDE4A,PDE4D,GPR85,GNG2,PIK3R1,ZNF655,FTO,PRRX1,MAGEL2,EPB41L4B,POU3F2,TMEM235,MINDY2,PPM1B,MAPK9,HYDIN,PRPSAP2,GON4L,PTCH1,ANKHD1,PLPPR1,PTN,PTPRG,TMEM231,USP47,ACSS3,ZNF793,SH3TC2,FAT4,ENOX1,RBBP6,RADX,RDX,TRIM68,RET,REV3L,RFX4,UBR7,RIT2,ZFHX4,MRAP2,GLDN,PRR5L,ACER3,RTN1,NCBP3,S100B,DGLUCY,SATB1,ATXN1,TNFRSF19,ELMOD1,IL17RB,ITSN1,KIF16B,CPEB3,NTNG1,FNDC3A,ST6GAL1,RUFY2,SLC6A1,SLC6A11,RADIL,CCDC88A,SMARCE1,INAVA,KIF13A,PDZRN3,UNC80,SON,SOX1,ZCCHC24,SOX11,NMNAT2,RAP1GAP2,SPART,C11orf87,SRPK2,TROVE2,LARP4,MAPK8IP3,SEPT8,SULF2,AJAP1,GSE1,SYT11,TACC1,KAZN,TAL1,AGTPBP1,TBL1X,TBX15,TRIM2,TCF12,FAM200B,SIRT1,ZFPM2,AKTIP,TIMP4,TLL2,ERCC6L2,KCTD2,TP53BP1,TPM1,RGMB,NR2C2,STXBP4,TRPC3,ANKRD20A2,ZKSCAN5,HIRA,FLRT2,CLDND1,ZBTB14,ZNF17,KCNT2,ZNF74,NDRG4,CELF4,EML6,EMSY,MFF,EVI5,STOX2,TUBA1A,ADAMTS9,NAV3,SLC17A6,EPM2A,GOPC,ST7,PAK5,KAT6A,NUP214,JMJD1C,RSPRY1,MSRB3,NHSL1,SLC39A12,KLHDC1,FRMD6,IFT88,NETO1" MicroRNA hsa-miR-3156:mirSVR_highEffct hsa-miR-3156:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.61E-125 9.03E-122 1.69E-124 1.55E-123 319 1318 "KCNH8,ACADM,ACLY,CLK4,KDM5D,CSMD3,NDRG3,DSCAML1,ERMN,KIAA1211,ADORA3,PTCHD1,SLC44A5,KIAA1324,ALCAM,ABCD2,ARHGAP20,FAM135A,AMPD3,KIF6,CDC42BPA,LCORL,APP,MIER1,ASPH,ZBTB10,TMEM108,ATP2B1,DPY19L3,ADAM23,ADGRB3,DCAF5,BMPR1B,DST,ST3GAL5,ARHGEF7,FUBP1,DDR1,CACNB2,KALRN,CANX,SYT6,CAST,ZNF501,LRBA,CDC27,CDC42,LRRFIP1,L3MBTL4,LOC730101,MAGI1,CHM,CASC2,SYNPR,RAB3C,JAM2,NDST3,RAB28,PLAA,NRXN1,FBXO7,HECTD1,MAP4K4,CNN3,MYRIP,CREM,HAPLN1,RNF14,ANKRD44,FEZ2,OSBPL3,SUSD5,FAM169A,PHF14,NRSN1,ST18,RUBCN,CCDC144A,FGFR1OP2,GAPVD1,RIPOR2,RASSF2,TBC1D5,MATR3,IST1,DGKB,PITPNC1,DCT,ZEB2,ZBTB24,CEP170,MAGI2,DDX46,RHOBTB1,SACS,RABGAP1L,CHRDL1,DLG2,DMTF1,ACOT8,DTNA,ABCC9,GOLT1B,EDNRA,FAM13A,PHF20L1,KCTD3,ELAVL2,C8orf37,KCNMB2,EXTL2,NRN1,ARMCX1,FABP7,SH3YL1,CEP78,FCGR3A,ZNF589,SEC24B,OLFM1,FGF13,TMEM164,POLK,RGPD5,EFCAB2,ATP2C1,CELF1,NSG1,NRG3,STAG2,ZNF44,GABRB1,BRPF3,ZMYND11,JPH4,DISC1,KIAA1841,SESN1,ADAM28,GGTA1P,PPARGC1A,MALT1,RUNDC3A,BRD8,HPGDS,SPIN1,GLS,CBX1,KCNMB4,GNAL,GPM6A,RAPGEF4,DIDO1,GRIA4,ADAMTS13,GRM8,KIF3A,TMEM25,ZBTB49,PSIP1,GUCY1A2,RASSF8,ATXN2L,ELOVL5,LIX1,ZNF678,SLC35G1,KCNA6,KCND2,KCNJ16,LAMP2,NCOA7,GPR155,MATN3,MBNL1,SYT9,MEIS1,MEIS2,CD200,ERICH3,MRPL42,COMMD5,ZNF92,MYO9A,NCAM1,NELL2,OTOGL,HCN1,NTRK3,CHAMP1,GPR137C,PAK3,PDE3B,PDGFRA,GNG2,ABCB1,PIK3R1,XRN1,PDZRN4,MAPKAP1,RC3H2,ING3,SPATA6,EPB41L4B,POU3F2,CRLS1,PPP3CB,CEP41,PRKCG,EPDR1,GRAMD1C,GDPD1,RELN,PLPPR1,TMEM260,PTPN13,PTPRB,PPP2R3C,ZNF793,FAT4,ZNF493,MSANTD2,SLC6A15,RFX3,PBRM1,RPRD1A,CCDC82,EXD2,ROBO2,RPL15,STK32B,ABCA11P,ATXN7,SCN2A,SCN3A,SOX6,SGK1,SH3GL2,CPEB3,SHMT2,HKDC1,CHD9,ZNF365,BTBD3,ZNF430,SCMH1,CPEB4,NAXD,LIMCH1,TMCC1,FAM126B,PDZRN3,DOK5,KIF1B,ZBTB43,NPAS3,CAMTA2,EPB41L3,NKAIN2,ERBIN,NXT2,ELOVL4,DIP2A,STXBP1,AJAP1,FGD4,TMEM150C,SYN2,COBL,ANKRD28,TACC1,TBL1X,KLHL4,TCEA1,EHBP1,ACSL6,TCF4,WASHC4,HIF3A,TEX15,ITGB3BP,TGFBR3,SLC44A1,HEY2,LRRC8A,TMOD1,TMPO,FAM124A,SEZ6L,TPM4,ELP5,STXBP4,ZMYND8,TTC3,TMEFF2,UBE2H,SLC35A4,UGT8,FLRT1,PLEKHH2,BCL2L13,TBC1D15,ZNF711,ZNF142,EML6,SYNC,UPF3A,WNK1,CADM2,STOX2,SNX27,WNK3,EPM2A,RGS7BP,RTN4,PAK5,SMIM8,CASC15,TRAM2-AS1" MicroRNA hsa-miR-3168:mirSVR_lowEffct hsa-miR-3168:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-125 1.30E-121 2.43E-124 2.23E-123 342 1512 "ASIC1,AS3MT,SLITRK1,TMCC3,SORCS1,ERMN,PLEKHH1,OLMALINC,HECW2,KLHL13,TBC1D14,CC2D2A,C1QTNF3,ALAD,SMIM17,SRPX,CEP126,OGT,ANK2,EP400,PPFIA1,AQP4,ARHGAP5,CAPRIN2,ATM,CCDC181,SLC4A4,N4BP2L1,DPY19L3,BCHE,BMPR1B,ARHGEF7,MTMR2,CA12,DDR1,CALM1,PTBP2,CAST,RUNX1T1,CBR1,CLDN10,ZBED1,FOXN3,CASC2,CNOT8,CLCN4,NMT2,NGEF,ARHGEF6,ARMC8,LETMD1,AKAP5,RCHY1,FAM171B,C2CD2,CREM,ENTPD4,CREB5,AKAP12,HAPLN1,TRIM69,CS,FEZ2,PHF14,CYBB,HDAC9,KATNAL2,TOX,MATR3,TOMM20,YTHDC1,JAKMIP2,MFAP3L,KLHL3,GSDME,RABGAP1L,DLG4,DMPK,OLIG1,USP3,NR1D2,DOCK2,ACOT8,PDCD6IP,ABCC9,GOLT1B,EBF1,EDNRA,RBM12,SH3GLB1,KMT5B,IRAK4,TENM1,PAN3,USPL1,EMX2,OLIG2,RCAN2,ZNF549,TMEM74,CEND1,KATNAL1,F5,FAM198B,ZNF461,WAC,TMEM132C,ACSL4,SCML2,CORO2B,DLC1,ATP8A1,FCGR3A,SLC9B2,POLR1B,FGF12,FGF13,MEX3B,FOXG1,PCYOX1,FOXO3,JKAMP,SORBS1,SMC2,APOPT1,UFM1,ATP2C1,CHL1,GABRG2,CAB39,FAM120B,RAPGEF6,NCKAP1,IQGAP2,MTHFD2,GATM,SPIN1,GLRB,ZNF638,GPM6B,LPAR4,GPR34,STMN2,ATE1,RNF165,GSTM5,GUCY1A2,IRAK3,RASSF8,NXPH2,FRMD3,HMGCR,HNRNPK,HSPA1L,NKD1,ZIC5,USP54,LIX1,IL6ST,ZNF385B,LRRTM1,KCNA4,KCND2,KCNJ11,KCNMA1,KIF2A,KIFC3,LAMP2,PAXBP1,LMO1,SYTL4,MARK1,MBD1,LRP1B,KCTD6,KITLG,MMP16,ADAM22,MSR1,DDX25,MTTP,NCAM2,ZC3H12B,NDUFA5,NEFM,NEUROD1,SLCO1C1,NFIA,CNOT4,NOVA1,NPTX1,NTRK2,DDR2,NUCB2,GLIPR1L2,PDE1C,PDE4D,NALCN,PIK3C2A,SNX10,PKM,PLCL1,FTO,LRP12,SCHIP1,SEPT4,EPB41L4B,TNPO2,MINDY2,CRLS1,PTPA,RANBP3L,PRKAB2,MAPK9,MASP1,BCAS3,PTCH1,PLPPR1,PTHLH,PTPRD,PTPRO,PEX5,CCDC40,ATG16L1,FAT4,RASGRF2,BSDC1,ERI2,RGS7,PRIMA1,RIC8B,LGI2,RAVER2,ROBO1,SNX22,ZC3H14,ACER3,TCP11L1,LRRK2,LGR4,SATB1,ATXN2,HOGA1,SCN2A,SCP2,TNFRSF19,SMPD3,SLC30A10,KIF16B,CPEB3,NTNG1,SHC4,NLGN1,RUFY2,RAB3GAP1,SLC9A5,SHANK2,SLC12A2,BTBD7,SPHKAP,SMARCC2,SMARCE1,ANKRD36,SNAP25,MAPKBP1,KIF13A,CMTR2,SNRPN,FAM126B,MYO16,KDM4C,KIF1B,ZBTB43,SPART,C11orf87,ITPRID2,SAMSN1,ERBIN,ELOVL4,SEPT3,NSFL1C,KLHL7,NECAB1,PRRC2C,C3orf70,COBL,ANKRD28,TACC1,KAZN,DDHD2,UNC5D,TBCEL,FBXW11,TBL1X,EHBP1,ACSL6,SATB2,TRIM2,SZT2,WDR7,SYNE1,DOCK9,TMEM151B,PCDHB9,PCDHB6,GPRIN3,HIF3A,TEK,HEY1,TLR4,HEY2,CSMD1,C5orf64,C9orf85,ZNF346,TRPC1,TRPC3,TRPS1,SSBP2,RPRM,UBE3A,SLAIN1,BCL2L13,WIPF1,NSD2,MICU3,ZBTB38,SLC30A4,RNF103,ITM2C,FAM47E,PDSS2,FZD3,PHTF2,CASC15,FAM219B,ADAMTSL3,NLRP3,TIGD6,SNX14,FRMD6,FAM198A" MicroRNA hsa-miR-138-2*:mirSVR_highEffct hsa-miR-138-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.97E-125 1.67E-121 3.10E-124 2.86E-123 331 1420 "ABAT,CSMD2,ADD3,CDC7,ESYT2,PTCHD1,GPR158,LRRC7,SMIM17,ABCD2,OGT,LCORL,PHF12,APAF1,APBA2,DGKZ,ALS2,TNRC6C,MIER1,TMEM263,TMEFF1,ASPA,NCOA1,NOL4,SNAI3-AS1,JAZF1,RAB29,CA8,CACNA1D,CANX,CAST,AIFM1,TMEM257,C1orf52,LRBA,CDH8,ZMYM4,CDH18,LGI1,LARGE1,CCPG1,CFL2,SRSF11,NDST3,SLIT2,TJP2,ABCG2,NIPBL,COL4A5,SLC4A8,TBPL1,IGDCC3,CHD1L,RBM39,SEC24C,FEZ1,CSNK1G3,SUSD5,VCAN,DZIP3,APPL1,GREB1,CFAP61,CTNND2,ST18,CCDC144A,TCAF1,RIPOR2,ARHGAP24,FRMPD4,TOX,ZFYVE16,KIAA0586,KCTD8,DGKB,DAPK1,DNAJC6,ALKBH8,PLPPR4,SV2A,NR1D2,DMTF1,PDCD6IP,DTNA,GOLT1B,E2F6,WDPCP,EDNRB,HIPK3,KLHL5,KMT5B,ING4,EMX2,RCAN2,EPHA5,ZNF549,EYA1,ABCA8,FCGR1A,CEP78,FER,MED12L,SUCO,FOXG1,SYNCRIP,FOXM1,FOXO3,UFM1,ARFGAP2,ERGIC3,KHDRBS3,ST6GALNAC3,CSPG5,MSANTD4,OGA,FYN,PHYHIPL,STAG2,DKK3,MEGF10,GABRA5,ILDR2,GAD1,HBS1L,AHCYL1,RAPGEF6,ARPP21,C15orf41,KIAA1841,LYVE1,SPIN1,RAB30,GLS,FERMT2,GPM6B,LPAR4,PCLO,RAPGEF4,GRIA2,DIDO1,GRIA4,RFFL,GRIK1,LINGO1,PSIP1,WIF1,MIER3,GABARAPL2,HSP90AA1,EID2B,MSL1,ZNF181,SOWAHA,IGF1,LRRCC1,PLD5,LIX1,IL6ST,ZNF385B,LRRTM1,SLC35G1,KCNB1,KCNK1,KCNK2,KIF5A,KLRC2,STXBP5,LIG4,ARHGAP12,SMAD1,LOC100128239,MARK1,MAT2A,MATN3,SYT9,KCTD6,MIA2,PPM1L,POC1B,COL28A1,SCG3,TAGLN3,MYO5A,MYO9A,NDP,NF1,SLC11A2,NRCAM,OGG1,OPCML,PDE3B,FAM98B,GDAP1L1,PIK3C2A,PIK3CD,A2ML1,XRN1,HMGCLL1,PRIMPOL,PDZRN4,RC3H2,ING3,RETREG2,SH3KBP1,POU3F2,PKN2,MAPK9,GRAMD1C,HYDIN,PROX1,MDGA2,CNTLN,PXK,TMEM260,FAM120C,SH3TC2,FAM184A,ARID4A,ZDHHC14,RFX4,KLHL11,RIC8B,RPRD1A,ZFHX4,RAVER2,CARF,ROBO1,ROBO2,ELP2,CCDC102B,NEK11,ACER3,STK32B,LRRK2,YJEFN3,ZNF568,TRAPPC13,MIR124-2HG,CSRNP3,SCN3A,SCP2,FNIP1,SOX6,SFPQ,FBXO11,FHOD3,WDR37,FAM81A,PPP4R3A,YPEL4,SEPHS1,CCDC88A,BTBD7,CPEB4,GKAP1,LIMCH1,SNAP25,SNCA,MBD5,CMTR2,USP33,PDZD2,TRERF1,TNIK,SP4,CAND2,KDM4C,RBM26,LMO3,SRPK2,TAB2,ATP10B,CLASP2,POGZ,NXT2,NEK4,RGL1,KLHL7,ZC3H4,ABCC8,PLCB1,ANKRD28,POPDC3,MTCL1,CAMTA1,ADGRL3,IQCE,TBL1X,EHBP1,TCF12,GPRIN3,ZFPM2,AP4E1,THRA,HEY1,TPD52,WBP2,RGMB,ANKRD20A2,TMEFF2,TUBB1,RPL7L1,BCL2L13,VGF,MEAF6,CCDC14,NSD2,RICTOR,PCDH20,MICU3,KCNT2,GPR158-AS1,MKRN3,ZBTB16,SMARCAD1,EMSY,EVI5,PRDM10,RNF103,VPS35L,FIP1L1,SLC17A6,GOPC,HNRNPA3,CERS6,ZNF248,NHSL1,FXR1,FRMD6,NETO1,DPF3" MicroRNA hsa-miR-2116*:mirSVR_lowEffct hsa-miR-2116*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.02E-125 1.69E-121 3.15E-124 2.90E-123 351 1591 "SDE2,ABCF1,ASPHD1,ABHD6,SYS1,CSMD3,ERMN,UNC5A,PTCHD1,SLC24A4,LRRC7,ALCAM,PDZD4,AMPH,ANK1,EP400,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB1,EPB41L5,GPAM,DGKD,ALS2,NT5C3B,PPFIA3,AQP6,SPTBN4,LINC00173,CAPRIN2,BRINP2,ATP2B1,B3GALT2,DPY19L3,SEC11C,BCL2L2,ST3GAL5,BTK,MTMR2,CACNA1G,GPC2,CA12,CALB2,PTBP2,TRIM41,CAPN3,VXN,CAST,RUNX1T1,LDB2,CERS5,INA,ARHGEF1,C1orf52,DGKI,REPS2,CDH2,CDH8,DLGAP1,IGFN1,NDST3,ZFYVE9,FAM189A2,QKI,CNR1,PCYT1B,ANKRD35,LETMD1,SLC35F1,SEC31B,C2CD2,SLC32A1,NCOR1,SNCAIP,FEZ2,FEZ1,PDE4DIP,CTH,CFAP61,CTNND1,CTNND2,PUM1,CCDC144A,NOS1AP,DCAF8,PHF19,EARS2,DGKB,AIF1L,ZEB2,CNIH3,FBXL5,BLOC1S6,POM121,SPOCK3,SRGAP3,NTM,RABGAP1L,KIF19,DLX1,EXOG,DMD,HS3ST2,NYAP1,DPYSL2,DRP2,ABCC9,FAM135B,EDNRB,CNNM1,KLHL5,CACNG7,FAM13A,GPR61,ABI2,AASS,ELAVL4,TUBD1,LRRC17,DENND4A,EFS,TLR7,EZH1,HSPA12B,F3,CLVS1,TUBB3,DLC1,FKTN,FECH,FGF1,SPSB4,FGFR3,CAMSAP1,PCYOX1,SEMA4D,ZCCHC17,NPTN,ATP6V1H,TVP23A,STAG2,MEGF11,CAB39,HBS1L,RAPGEF6,ARPP21,C15orf41,INPP5K,WASF3,GCK,DHRS4,RAB30,TNRC6A,MAP7D2,DCLK2,LOXL3,GOLGB1,LILRA1,CECR2,GRIA4,RFFL,NR3C1,CELF3,RASSF8,HAS2,HPS5,ZHX1,ATXN2L,KLF12,HLF,DHX35,SMAP1,MSL1,MYLK2,IGSF1,ZNF678,ITGAV,A1BG-AS1,IPO5,LMO1,VWA5A,NCOA7,NAT8L,LOC100128239,MAOB,MAPT,MBP,MEIS1,KITLG,WDR49,ZNF680,MYO9A,RTL5,NCAM2,ZC3H12B,NUCB2,GPR88,CHAMP1,LOC100128398,CLDN11,ZNF713,ZDHHC22,ETFRF1,PCSK5,PDE2A,PIRT,BEST3,PFKFB3,A2ML1,XRN1,HMGCLL1,MTRF1L,PMP2,SPATA6,SH3KBP1,POLR2F,POU3F2,CCDC144B,MAPK7,APTX,SNRK,CNTLN,BDNF-AS,ELOVL2,PTPRE,PTPRG,PTPRH,PTPRO,C1orf109,RAB3A,SH3TC2,C1orf54,ZCWPW1,ROGDI,ARID4A,RADX,ZYG11B,UBR7,RGS4,ARHGEF10L,KIF7,MRPS18A,RNF220,RIC8B,PBRM1,RPRD1A,CARF,KIRREL1,RORB,TMEM206,ELP2,RPE65,TMEM100,SPIN3,GLDN,PRR5L,PAQR6,HUNK,MIR124-2HG,SEMA6D,SCN2A,PEAR1,SOX6,ASRGL1,ZFP30,FRMPD1,DOCK10,SHC4,FNDC3A,NUBPL,SLA,ZNF365,SLC1A3,SLC1A7,NBPF1,SLC9A5,SLC14A1,TMEM132D,SLC22A4,RCOR3,SNCB,MBD5,SNRPN,PDZD2,SOX2,BDP1,KDM4C,TSPYL2,NFASC,CLASP2,CAMTA2,STOX1,ZSCAN29,KANK1,FGD4,ARHGEF9,SYN2,SYP,POPDC3,TACR1,ANKRD12,UNC5D,TBCEL,TCEA1,TCF4,ZEB1,TPCN2,TMEM151B,TNS2,TEK,PMS2CL,AP4E1,CDH22,MTMR14,TMEM9,ZFP91,TNFRSF1B,NPL,ZNF346,ELP5,ZMYND8,TMPRSS5,UBTF,USP1,PLPPR2,MEAF6,XPO1,LGI4,ZIC3,ZNF24,TRIM9,SLC26A10,ZNF138,ZBTB16,ZNF154,POLR3H,PCBP1-AS1,PLPPR5,KCNAB1,WIPF2,HRASLS,FAM13C,TMEM63C,CASC15,CERS6,ADAMTSL3,ZNF248,RNF170,PIANP,DPF3,LAS1L" MicroRNA hsa-miR-155*:mirSVR_highEffct hsa-miR-155*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.07E-125 1.73E-121 3.20E-124 2.95E-123 310 1248 "SYN3,NCKAP5,CSMD2,SLITRK1,BRAP,ADORA2A,KIAA1211,RNF150,KLHL13,CC2D2A,HFM1,C1QTNF3,LRCH2,ANK2,EP400,LCORL,USP28,PPFIA4,TMEM263,CASK,RGS20,MARCH3,BRINP2,ATP1B3,N4BP2L1,ZNF599,BMPR1B,DST,NAE1,SCAPER,CA8,CACNA1E,CACNB4,LURAP1,PTBP2,CAMK2D,TRIM41,PRC1,CLDN10,KRIT1,USP6,INA,CBFA2T2,SCARB1,SEPT7,CDC27,CDH8,CDH10,LRRFIP1,NOG,CFL2,ADGRG1,SRSF11,CHN2,NDST3,DNAJB5,SULT4A1,AKAP6,COL4A5,SLC4A8,ABI3BP,PREPL,ANKRD44,GDA,FEZ1,ARHGEF10,ATRNL1,SIPA1L1,PHF14,CTH,GREB1,CTNND1,HDAC9,FRMPD4,KIAA0586,DAPK1,PABPC5,DNAJC6,C8orf34,MAGI2,ZC3H11A,ALKBH8,SGSM2,CHRDL1,USP3,DPYSL2,PDCD6IP,RCAN1,DNAJB6,ABCC5,ABCC9,EDIL3,WDPCP,EDNRA,ANKRD46,KLHL5,GPR61,GOLGA7,DCTN4,LRRC17,MTSS1L,IGSF6,CEP85L,F3,ABCA8,FABP7,DLC1,FCGR1A,MED12L,TMEM164,FHL1,FOXG1,JKAMP,NBEA,DACH2,SARAF,NRG3,MPP6,ABLIM2,STAG2,MEGF10,B4GALNT1,NEK6,ZNF559,DISC1,LRRC37A6P,MALT1,GK,TCERG1,DBF4,RAB30,ZNF638,LNX1,GPM6A,LILRA2,GPR17,RAPGEF4,GRIA2,GRIK1,ATE1,RNFT2,MAEL,BACH2,ELOVL5,HNRNPK,HSP90AA1,SMAP1,HTR2A,MSL1,ZNF181,LRRCC1,USP54,ZNF385B,ITGAM,ITGAV,JAK1,KCND2,KCNK1,CREG2,KIF5C,STXBP5,STMN1,LIG4,MBD1,MBNL1,MEF2C,MGAT3,AFDN,CD200,BLOC1S2,ZNF92,NDUFA5,NEUROD2,NF1,NME4,NPTX2,HCN1,ZNF713,GLIPR1L2,ETFRF1,ENPP2,PIK3R1,FAM218A,PLCL1,HMGCLL1,PDZRN4,LRP12,EPB41L4B,NXPH1,MED1,TATDN3,MAPK9,HYDIN,DCHS2,LRRC49,SNRK,MDGA2,CNTLN,TMEM260,PEX5,USP47,OXR1,RDX,TRIM68,REV3L,ERI2,GTDC1,RFX4,UBR7,RGS12,SLC25A36,TMLHE,C12orf49,CARF,RORB,ARMH4,SPIN3,FOXRED2,TNFRSF19,ZFP2,SUPT20H,NLGN4Y,ITSN1,FHOD3,SLITRK3,SEC31A,SLC6A1,RAB3GAP1,CCDC88A,SLC11A1,ZNF334,SLC22A4,SLN,PALLD,UNC80,USP33,PEG10,LMO3,TAB2,ZNF302,ZSCAN29,NEK4,ADHFE1,SEPT3,FGD4,SYNE2,PLCB1,SYPL1,C12orf76,DDHD2,DNMBP,TAL1,ADGRL3,AGTPBP1,TPCN2,TRIM2,WASHC4,CLASP1,SYNE1,PCDHB6,FRYL,TEX15,SIK3,RNF216P1,DNAH7,CRB1,AKTIP,ASXL3,BHLHB9,ERCC6L2,TMOD1,RBFOX2,TPM1,SYNPO2,METTL3,STXBP4,ANKRD20A2,ANO5,TMEFF2,HIRA,TUBB1,CADM1,UBTF,UGT8,PITPNB,ZNF781,PORCN,XRCC4,ZBTB14,ZNF28,CELF4,ZNF154,ZSCAN26,FTSJ1,SMARCAD1,EMSY,PCDH15,PLSCR4,GOPC,FAM13C,AMN1,FZD3,DOCK8,RTN4,UBE3B,PAK5,VANGL2,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-548q:mirSVR_lowEffct hsa-miR-548q:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-125 1.74E-121 3.23E-124 2.97E-123 333 1437 "DGCR6,ASIC1,ACTN1,FMNL2,GALNT13,ADORA2A,PTCHD1,KIDINS220,SLC24A4,AP1B1,KIAA1324,LRRC7,ALAD,SEMA6A,ARHGAP20,OGT,ANK1,FGD2,PPFIA1,UPRT,CDK10,CDK13,MARK4,NCOA1,ATM,B3GALT2,DPY19L3,MYOM1,DOCK11,ADAM23,TTLL9,BACH1,SNAI3-AS1,LINC00847,SYNJ2,ARHGEF7,CA4,VXN,VSTM2A,ISPD,SPAG9,CLDN10,TMEM257,CDC42,ARHGAP33,TIGD7,CHI3L2,SYNPR,CHRNA4,SLC24A2,TPP1,DGCR9,QKI,SRP14-AS1,HECTD1,CNGA3,FAM149A,AKAP6,BTF3L4,RCHY1,TBPL1,TCEAL2,TOGARAM2,CNRIP1,ENTPD4,CRHBP,GDA,CLIP3,ABCG1,CSF2RA,FEZ1,ATRNL1,PLCH2,SOCS5,CST3,CTH,GREB1,NRSN1,SEC14L5,FGFR1OP2,TM9SF4,MATR3,MAML1,IST1,GIT2,PITPNC1,MFAP3L,C2CD2L,SRGAP3,MED12,PDCD6IP,DTNA,MAMLD1,DNAJB6,ABCC9,SGK2,FCF1,HEYL,SH3GLB1,RASA4,ASB3,EIF5,ELAVL3,TNK2,ELN,C3orf18,EML1,DCTN4,EIF1,ENO2,EPB41,LRRC17,MTSS1L,SEZ6,ANKRD13B,REEP2,CORO2B,FCGR1B,ST3GAL6,CEP78,STRADA,ZNF589,OLFM1,AMOTL2,MEX3B,HPCAL4,EVL,TPK1,CAMKK2,KHDRBS3,B3GAT1,NRG3,GABRB1,CAB39,RAPGEF6,ARPP21,IP6K3,IQGAP2,ERAP1,LRRC37A6P,CPLX1,GATM,ALDH1L1,ADAM28,GFRA2,PCDH17,PPARGC1A,MALT1,BRD8,CRCP,GLI2,CBX1,KDM2B,KCNMB4,FERMT2,GPT2,GPR37,PCLO,GRB10,GRIK1,GRM2,GRM7,LINC01551,RABL2A,ADAMTS6,ZHX1,GPR45,MIER3,HMGCL,HNRNPK,CPT1C,FAM95B1,RBPJ,KNDC1,ZNF678,JAK1,KCNJ10,KCNK1,GATD1,STXBP5,INSYN2,MAN2A2,MAP2,MBNL1,SYT9,MEIS1,AFF1,XRRA1,MOV10,MXI1,ZC3H12B,NNAT,NME4,SLC11A2,NUCB2,PBX1,DPY19L2P2,CDK18,PDE3A,PDE3B,PIRT,NALCN,PLCB2,FTO,SLC25A23,SCHIP1,SEPT4,SLC36A4,KANSL1,VSTM2L,CEP41,EPDR1,HYDIN,SIDT1,TMEM104,PIGG,CNTLN,PTCH1,BDNF-AS,TMEM260,PTPN13,PTPRE,C1orf109,TUG1,SLC25A48,RASGRF2,MSANTD2,ZYG11B,TRIM68,ERI2,RFX4,UBR7,RGS10,RGS12,CYB561D1,RORB,MCMBP,ADAL,CNTNAP3,RPS20,ATAT1,KCNIP3,NCBP3,SAFB,SALL1,ATXN7,LRRTM4,ASIC4,NLGN4Y,PPP1R9A,FERMT1,BCAN,NLGN1,WDR37,RPH3A,SLC11A1,NAPB,CPEB4,EPC1,SMARCE1,RCOR3,RIMS1,KIF13A,CABCOCO1,SNRPN,PALLD,SCN3B,NMNAT2,CLUAP1,LHFPL4,TEX2,PEG10,DBNDD2,SPTB,CDK19,TAB2,ATP10B,PBLD,SMOC1,ST5,MAPK8IP3,SEPT8,RGL1,GSE1,NECAB1,SYN2,SLC37A2,ASTN2,TACC1,MLST8,WWC1,TBCEL,TCF4,TRIM2,HIF3A,SPX,AP4E1,TMEM9,TK2,TLL2,BHLHB9,RIMBP2,KAT6B,PIK3R5,TPM1,CDK20,RGMB,ANO5,HSPBP1,RPL7L1,OSBP2,FLRT2,MEAF6,BEST1,SLC13A3,XRCC4,ZFP37,CFAP52,ZNF74,ZBTB38,ANKS1B,ZNF213,ZFAND5,WNK1,CSDE1,STMN4,TMEM178A,CIAPIN1,SNX27,FIP1L1,RGS7BP,JMJD1C,IFT88" MicroRNA hsa-miR-488:mirSVR_highEffct hsa-miR-488:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.38E-125 2.46E-121 4.54E-124 4.19E-123 322 1347 "TTYH1,CSMD3,FMNL2,ADARB2,CDC7,SORCS1,ERMN,ADORA2A,PWWP2A,ADRB2,KIDINS220,GPR158,HECW2,KLHL13,LRRC7,SMIM17,ABCD2,PCDH10,ANK3,FGD2,CCDC146,PPFIA1,ANXA7,APBA2,ALS2,AQP4,CADPS,DDX3Y,SLC4A4,ATP2B1,DPY19L3,ADAM23,BCL7A,SYNJ1,ST3GAL5,ARHGEF7,FUBP1,THSD7A,PTBP2,CANX,MAP7,CCNH,INA,CDC42,LGI1,CCPG1,SRSF11,CHN2,CHRM1,NDST3,NRXN3,FAM19A5,SLC4A7,ABI3BP,RCHY1,PREPL,CRHBP,HAPLN1,LRIG1,ARHGEF10,PHACTR3,PHF14,CTH,CFAP61,CCDC144A,CYBB,HDAC9,GPRASP1,TCAF1,ZNF337,PITPNC1,ARMCX2,HEPH,FBXL5,CEP170,KLHL3,WDR20,SEC16A,DMD,USP3,SLC12A6,MAMLD1,DYRK1A,E2F6,EBF1,WDPCP,ANKRD46,KLHL5,FSD1L,EFNB3,ELAVL2,PLEKHA1,VPS13B,RAB9B,TLR7,CLVS1,FAM198B,FABP7,ACSL4,CORO2B,CEP78,GORAB,FGFR3,TMEM164,UBE2E3,SLC37A3,SYT3,TACC2,SMC2,UFM1,FAM49B,TPK1,NPTN,KHDRBS3,MSANTD4,SDCBP2,STAG2,DKK3,GABRA2,GABRB1,GABRB3,RAPGEF6,NEK6,DISC1,IGSF5,SRCAP,SULT1C4,ARFIP1,PPARGC1A,GLI2,GLRB,TOX3,GNAO1,GOLGB1,PRRC2B,TDRKH,FUT10,STON1,RAPGEF4,GRIN2D,GUCY1A2,ADAMTS6,GUCY1B1,GYG1,WIF1,HAS2,TNFAIP8L3,HLF,HMGB1,SHISA6,HTR5A,MSL1,ZNF546,IGF1,ZIC5,TJAP1,PLD5,SCIN,DIPK1A,INPP5B,LRRTM3,KCNJ10,STXBP5,CYP27C1,KTN1,MAP2,MARK1,MBNL1,SYT9,SESN3,TMEM249,TAGLN3,CTNNA3,RSPO2,RTL5,NAP1L1,NAP1L3,CCDC13,NEK1,NF1,SLCO1C1,SMIM11A,NUMA1,SETD4,GPR88,ZNF827,SNTG1,PAK3,PCDH9,PRTG,PDE1C,PDYN,GNG2,PFKFB3,RETREG1,GPSM2,PLIN1,PLP1,PCDH18,PRIMPOL,LRP12,EPB41L4B,POU3F4,MED1,PPM1B,PPP2R5C,PPP3CB,PKIA,MAPK9,GRAMD1C,DIRAS2,RELN,MDGA2,QRICH1,CNTLN,ANKHD1,BDNF-AS,TMEM260,PTPRE,ZNF844,RBBP8,HKR1,KHDRBS2,ERI2,FIGN,RFX4,RGS4,RGS7,CCDC82,ZNF532,RERGL,EXD2,RAVER2,RORB,RPL15,SGSM1,PRR5L,STK32B,LGR4,ATAT1,NCBP3,AP1AR,SALL1,SCN2A,LINC00461,TRA2B,FERMT1,SHC4,SLC14A1,BTBD7,CDK5RAP2,INTS9,MBD5,CABCOCO1,MYO16,MYT1L,SOX5,BDP1,PEG10,NPAS3,TROVE2,EPB41L3,NKAIN2,ERBIN,MPRIP,RGL1,GANAB,NECAB1,FGD4,JMJD6,SYN2,SYT1,ANKRD28,POPDC3,ANKRD12,CAMTA1,CAMSAP2,WWC1,ANO4,EHBP1,WASHC4,PCDHGA11,SLC19A3,PCDHB4,FRYL,DICER1,CRB1,SLC44A1,TIAM1,ZFP91,TMOD1,TRIO,AMACR,CLHC1,HEPACAM,UBC,CADM1,PLEKHH2,USP1,MEAF6,NPDC1,RICTOR,ZIC1,ZNF711,AGMO,ZBTB38,ANKS1B,ZNF195,SYNC,UPF3A,PRDM10,LMAN2L,HPS4,SLC17A7,SNX27,KCNAB1,CAB39L,WNK3,KAT6A,SMIM8,PIANP,NETO2" MicroRNA hsa-miR-429:PITA hsa-miR-429:PITA_TOP PITA 5.53E-125 3.11E-121 5.73E-124 5.28E-123 252 818 "ABAT,SYS1,XKR4,CSMD3,ADCY2,SLITRK1,ADD3,SLC12A5,USP31,PTCHD1,NLGN4X,SLC24A4,GPR158,GPRASP2,ANK3,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,DDX3Y,SLC4A4,ATP2B1,SYNJ1,FUBP1,JAZF1,SGCE,FOXK1,CACNB2,CACNB4,THSD7A,CDC42,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,KMT2C,FAM19A5,DNAJB5,MAP4K4,CNN3,CNTFR,SLC25A27,BTF3L4,COL9A2,SLC4A7,CRHBP,CREB5,NCOR2,FEZ2,CSNK1G3,PHACTR3,PLCXD3,CTNND2,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,RIMS3,KCTD8,IP6K1,GIT2,ZEB2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,ELAVL2,PAN3,EPS8,ERBB4,TAOK3,DLC1,TESK2,AMOTL2,PRKAG2,MEX3B,FOXG1,FOXF2,SGIP1,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,CAB39,WASF3,SESN1,PPARGC1A,COPS8,FERMT2,GPM6A,CECR2,GRB10,CIT,PSIP1,MAP4K5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HMGB1,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,NCOA7,MAP2,LRP1B,AFF1,ERICH3,MYCN,MYT1,NAP1L2,NCAM1,ZC3H12B,NFIA,OTOGL,NFYA,CNOT4,NOVA1,NPTX1,HCN1,GPR137C,PCDH8,PCSK2,PDPK1,ANLN,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,FAT3,NXPH1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,UHRF1BP1,PTPN13,FAM120C,PTPRZ1,OXR1,ARID4A,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,LRRTM4,SUPT20H,ITSN1,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,SLC1A2,RUFY2,SLC6A1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,SOX1,SOX2,ZCCHC24,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,GSE1,SYT1,ANKRD28,CAMSAP2,WWC1,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,RALYL,PSD3,PUM2,FRYL,ZFPM2,TLL2,ERCC6L2,LRRC8A,RBFOX2,NR2C2,TMEFF2,SLAIN1,VLDLR,TBC1D15,WIPF1,NSD2,ZIC3,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,GOPC,PAK5,PHTF2,CERS6,FXR1,GAN,SENP7" MicroRNA hsa-miR-302d*:mirSVR_highEffct hsa-miR-302d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.59E-125 4.26E-121 7.85E-124 7.23E-123 320 1333 "KDM5D,KLHL32,SLITRK1,GALNT13,ERMN,PWWP2A,ADRB2,ZNF608,INTS2,MTUS1,CASKIN1,NME5,NR0B1,C1QTNF3,LRRC7,ALCAM,ABCD2,FAM135A,PITPNM2,CDC42BPA,ANK1,ANK2,USP28,PPFIA1,PKP4,APBB2,MAGEE2,BCAS1,TNRC6C,APP,PPP4R4,PDXK,IGDCC4,TMEFF1,ARNTL,RGS20,ATP1A2,ATP1B3,ATP2B1,ZNF583,N4BP2L1,DOCK11,ADGRB3,ZNF599,SYNJ1,SCAPER,WASF1,CALB1,PTBP2,CAMK2D,ISPD,RUNX1T1,METTL6,REPS2,TIGD7,CIART,CFL2,SRSF11,SYNPR,NRXN3,HECTD1,SLC25A27,SLC4A8,IGDCC3,CNRIP1,CP,CHD1L,PREPL,HINFP,GDA,SNCAIP,CSF1,ARHGEF10,OSBPL3,PDE4DIP,APPL1,UBXN2A,CTNND2,DCAF4,RUBCN,DOCK4,HDAC9,GPRASP1,ARHGAP32,FGFR1OP2,TCAF1,FRMPD4,PHF19,EARS2,KIAA0586,IST1,DNAJC6,MYEF2,LYPD1,PLPPR4,SNAP91,CHRDL1,DLG2,NR1D2,CPEB2,DSCAM,ABCC9,GOLT1B,ANKRD46,EEF1D,PHF20L1,TENM1,PLEKHA1,CALCRL,EN2,TUBD1,LRRC17,KCNMB2,GPHN,FAM198B,TAOK3,DLC1,ST3GAL6,SLC9B2,FGF13,FGF14,FGFR1,FGFR3,SUCO,MEX3B,FOXF2,C2orf88,NBEA,FAM49B,ATP2C1,KHDRBS3,DACH2,ST6GALNAC3,STAU2,NRG3,ABLIM2,STAG2,GABRA2,GABRB3,GAD1,SALL3,NCKAP1,DISC1,IGSF5,ADAM28,MALT1,DBF4,SPIN1,TNRC6A,ZNF638,FERMT2,GPR22,EML4,RAPGEF4,GRIA2,NR3C1,GRM1,PRDM5,FAM19A2,RNF165,LINC01551,ATG4C,HMGCR,HSF2,IDH3A,ZNF546,LRRCC1,JAK2,KCNC1,KCNJ3,KCNK2,KCNMA1,CYP27C1,LAMP2,HECTD2,SMAD1,LYPLAL1,MDM4,AFDN,ZNF680,SESN3,CCDC80,MTTP,HNRNPM,P2RY13,NCAM1,NDUFA5,OTOGL,NODAL,NOS1,LRIT2,HCN1,NUCB2,CHAMP1,OPHN1,PAX6,PCDH9,PDCD2,PDE4D,PDGFRA,GNG2,ANLN,SNX10,RETREG1,PLP1,HMGCLL1,PURG,ANKRD16,TRHDE,RC3H2,PRRX1,ING3,EPB41L4B,POU3F2,PPM1B,PCDHB17P,PPP2R5C,KANSL1,GRAMD1C,DIRAS2,PROX1,RELN,TMEM260,ZSCAN32,PTPRB,SH3TC2,NWD1,RASGRF2,RBBP8,RADX,KHDRBS2,MSANTD2,RGS7,SLC25A36,PBRM1,ZFHX4,KLHDC8A,RAVER2,ROBO2,RPL15,ABCA11P,SOX8,RYR3,SCN3A,SFPQ,SUPT20H,SGK1,ZFP30,DOCK10,SHC4,MAGI3,FNDC3A,SEC31A,SLC1A3,PPP4R3A,EPN2,RADIL,SHANK2,ATF7IP,SLIT1,ANKRD36,MBD5,SNRPN,PDZRN3,SON,BDP1,EMC1,ZNF423,ZC3H13,SPTAN1,CDK19,MCF2L2,SRPK2,ATP10B,ITPRID2,LARP4,ELOVL4,SEPT8,SYT11,VPS13A,DDHD2,PDLIM2,TCEA1,TRIM2,RALYL,ZMAT3,SLC44A1,ASXL3,TLL2,ERCC6L2,C5orf64,TNS1,TPM1,METTL3,DCBLD1,FRRS1L,P2RY12,ZNF781,ZNF711,ZNF17,ZNF23,ZNF45,CELF4,FSTL5,EML6,SMARCAD1,UPF3A,WNK1,PCDH15,KCNAB1,WNK3,PLSCR4,PDSS2,EPM2A,DOCK8,JMJD1C,KLHDC1,RNF146,CBLN2,ST8SIA2" MicroRNA hsa-miR-148a*:mirSVR_highEffct hsa-miR-148a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-124 6.20E-121 1.14E-123 1.05E-122 346 1554 "KCNH8,ACADM,CLK4,ARID1A,PTCHD1,INTS2,GPR158,PCDH19,KCTD16,HFM1,OGT,PKP4,GPAM,USP37,MIER1,ARNTL,PLA2G4C,ZBTB10,EIF4G3,ATP1B3,ATP2A2,ATP2B2,ADAM23,BACH1,CDK5R1,DST,IL33,CA12,CACNA1D,DDR1,KALRN,CANX,SLC25A14,CLDN10,INA,C1orf52,AP4M1,LARGE1,CHGB,CHM,KMT2C,IGFBP7-AS1,PPT2,TPP1,NGEF,ABCG2,HECTD1,TMEM155,CNN3,FAM149A,BTF3L4,LETMD1,AKAP5,RTTN,CHD1L,NCOR1,GDA,SNCAIP,CSNK1E,SOCS5,CST3,FAM169A,APPL1,UBXN2A,PHF14,PUM1,ZSCAN23,DCAF4,EDRF1,CX3CR1,ARHGAP32,KATNAL2,TOX,LONRF1,MATR3,KIAA0586,TOMM20,PITPNC1,FBXL5,ALKBH8,SPOCK3,NTM,G3BP2,RABGAP1L,WDR20,DLG2,USP3,DNAH9,NR1D2,DOCK2,CASP8AP2,DPP6,GNE,TOM1,WDPCP,CNNM1,FRY,RBM12,FAM13A,EGFR,KMT5B,COPS4,ELAVL2,EML1,PAN3,USPL1,TUBD1,RCAN2,ERCC2,TMEM74,RCSD1,CEP78,ZNF589,SEC24B,KIAA1109,FGF11,FGF13,PRKAG2,UBE2E3,VTI1B,SYNCRIP,FLT1,SGIP1,NBEA,PDLIM5,ATP2C1,CELF1,CGREF1,STAU2,FYB1,ZMAT1,STAG2,MEGF10,CHL1,GABRB1,GABRG2,CAB39,IQGAP2,ERAP1,DNER,GDF9,ADAM28,PPARGC1A,RAB30,GLRB,MSL3,PCDH11X,PRUNE2,FUT10,STMN2,GRIA1,DIDO1,GRIA4,ATE1,GRM1,GRM3,KIF3A,FAM19A2,ZBTB49,IRAK3,RASSF8,UBE2QL1,ZHX1,FRMD5,ELOVL5,HMGB1,HMGCL,HMGCR,OPALIN,CELF5,IDH3A,DOCK7,LRRCC1,PLD5,USP54,SCIN,LIX1,LRRTM1,SLC35G1,KCND2,KCNK1,KCNN2,KIFC3,PAXBP1,MAP4,MBNL1,MEST,AFDN,MN1,DDX25,MYO9A,NF1,OTOGL,CNOT4,NOVA1,SLC11A2,NRCAM,NTRK3,NUCB2,GPR88,OPHN1,CLDN11,ZDHHC22,ETFRF1,PDGFRA,PDPK1,PDYN,BEST3,CYTL1,ABCB1,PIK3C2A,ANLN,ZNF655,TMEM38A,FAM216A,HMGCLL1,RC3H2,SDK2,SPATA6,TNPO2,TMEM235,PPP2R2B,PPP2R5E,RASGEF1B,CEP41,PRKCG,GRAMD1C,SNRK,BDNF-AS,PTHLH,TMEM260,PTPRD,PTPRG,RAD17,ATG16L1,FAT4,OXR1,RBBP6,BSDC1,ERI2,GTDC1,RGS12,SEC61A2,DCUN1D2,TMLHE,EXD2,CARF,GSTCD,RORB,CCDC102B,SNX22,ZC3H14,LRRK2,CNTNAP3,CLIP1,TRAPPC13,AMER2,FAM19A1,LINC00461,FNIP1,KIF27,SCAF8,NLGN4Y,ZFP30,FERMT1,KIF16B,CPEB3,DOCK10,CHD9,FNDC3A,ST6GAL1,NLGN1,ST3GAL3,ABLIM3,WDR47,RAB3GAP1,CCDC88A,NAPB,BTBD7,ZFP1,SMARCE1,RCOR3,UNC80,TNIK,BDP1,KDM3A,SP4,KDM4C,ERC1,SPTAN1,KIF1B,TROVE2,NKAIN2,KANK1,STXBP1,PRRC2C,VPS13A,PLCB1,UNC5D,ADGRL3,TBCEL,VWC2,SATB2,CUX2,ZEB1,TRIM2,TCF12,CLASP1,NAT16,PCDHB9,FRYL,CRB1,ZMAT3,TMOD1,C5orf64,RUNDC3B,TRPS1,TSN,CLHC1,SGK3,UBE3A,SLAIN1,CCDC14,VLDLR,WIPF1,SLC47A2,CFAP52,TCEAL7,ZNF142,REEP1,SPIRE1,UPF3A,ZNF225,EMSY,LINC02210,PRDM10,TMEM178A,PCDH15,KCNAB1,FZD3,DOCK8,SMIM8,PHTF2,ADAMTSL3,NETO1,SENP7" MicroRNA hsa-miR-28-5p:mirSVR_lowEffct hsa-miR-28-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.69E-124 9.47E-121 1.74E-123 1.60E-122 359 1670 "KCNH8,ASPHD1,NBAT1,NDRG2,ADCY2,SLITRK1,ADCY6,CCDC85A,ADD2,SORCS1,PLEKHH1,AP2A2,AP1B1,ZNF608,GPR158,CC2D2A,AK2,ADGRF5,PCDH10,SYT13,KIF6,ANK2,EP400,LCORL,SUGT1P4-STRA6LP-CCDC180,VAT1L,CDK10,IGDCC4,MARCH3,BRINP2,STX16,N4BP2L1,ADAM15,KSR1,CDK5R1,SYNJ2,CASTOR3,MTMR2,BTRC,KALRN,NGB,VXN,CBFA2T2,CD38,ENTPD6,LRBA,CDH18,MAGI1,FOXN3,CHN1,PLEKHB1,CASC2,SYNPR,JAM2,TAOK2,RAB28,KIAA1549L,CLCN4,CLTA,FBXO7,QKI,TMEM184B,LY86,FAM149A,WHRN,TOGARAM2,MFSD4A,CHD1L,SH2B1,CRY2,CLIP3,AATK,ARHGEF10,ATRNL1,GALNT9,VCAN,RIMS4,PDE4DIP,SLITRK5,PITPNM3,SDC3,CMTM5,CTH,ECE2,CCDC144A,NOS1AP,DOCK4,ARHGAP32,HDAC4,RIMS3,IST1,SPATA2,ELMSAN1,DGCR5,ZEB2,HEPH,MYEF2,HP1BP3,GSDME,RHOBTB1,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DNM1,HS3ST2,DYNC1I1,CDON,DPH1,E2F6,FAM135B,PHC2,HIPK3,CACNG7,SH3GLB1,EFNB3,EGR3,RASA4,C3orf18,EPHB1,KCNMB2,SRRM1,MRPL37,TLR7,SIRPB1,EZH1,WAC,PTK2B,TUBB4A,ATP8A1,FCGRT,FKTN,FDFT1,ZNF589,MED12L,OLFM1,FGF11,SUCO,UBE2E3,C1orf61,PCYOX1,ZMYND15,ATP13A4,FLT1,PSD2,FLYWCH1,SYT3,C2orf88,WDR83,JKAMP,USP21,ZNF605,NSG2,ZNF512,DKK3,MEGF10,GAA,GABBR1,CHL1,GABRB3,ARPP21,GAP43,DISC1,GATM,ALDH1L1,SESN1,KIRREL3,DHRS4,RAB30,TOX3,TNRC6A,MSL3,ZNF638,ADGRA3,LILRB4,PRUNE2,GRIA4,GRM1,PRDM5,GRM5,CIT,BTN2A1,ZBTB49,FAM107A,SLC2A6,WIF1,MUM1,PTGDR2,HMGCL,AGBL5,SHISA6,ZIC5,DOCK7,PLD5,IGSF1,DIPK1A,LRRTM3,JAK1,METTL21A,KCNK1,KCNK3,CREG2,IPO5,CYP27C1,SYTL4,LDLRAD3,SCAMP5,AFF1,MOG,TAGLN3,MYH7,MYT1,NCAM1,NEUROD1,NF1,NNAT,NOS1,SMIM11A,NUCB2,GPR88,LOC100128398,CDK18,PDE4A,PDE1B,PDGFRA,GNG2,BEST3,PFKFB2,PFKFB3,OLA1,CDK14,GDAP1L1,PIK3R1,ZFYVE21,KCTD15,ST8SIA5,EPN1,PURG,PRIMPOL,C11orf49,ING3,SH3KBP1,POLR2F,POU6F1,PPARA,PTPA,PRKAB2,CEP41,MAPK4,EPDR1,GRAMD1C,MASP1,TMEM104,STK32A,PEX2,NKAIN1,TMEM231,ZNF793,RAP1GDS1,RASGRF2,ZDHHC14,DPF2,ERI2,GTDC1,RFX4,RFX5,RGS3,RGS4,RNF220,KLHDC8A,ALG9,ARMC5,NEK11,RPL15,MCMBP,ATP8B4,NCBP3,FAM192A,CSRNP3,ATXN1,PRCD,SCP2,SOX6,SELL,GALNT10,SH3GL2,FERMT1,NTNG1,SYBU,SLC1A7,URGCP,PREX2,SLC6A1,ARHGEF40,LGI3,NAXD,GKAP1,SMARCC2,INAVA,SNRPN,UNC80,KDM4C,IDI2-AS1,IQSEC2,ZBTB43,RBM26,TAB2,CLASP2,ZC4H2,NXT2,ZSCAN29,KANK1,SEPT3,SYT11,JMJD6,PRRC2C,VPS13A,SYN2,POPDC3,ROBO3,DNMBP,VWA3A,TCF4,RPGRIP1L,SYNE1,NSD1,CCDC173,AP4E1,GZF1,TIE1,ASXL3,FAM124A,NPL,SMUG1,NEIL2,TRPC3,TRPS1,SSBP2,RFTN2,PRR18,RPL7L1,UBTF,DNAJC12,CCDC14,SF1,ZNF19,SLC26A10,REEP1,AMZ1,PLPPR5,SYNC,URM1,WIPF2,ST7,UBE3B,SSPN,FAM198A,JPH3" MicroRNA hsa-miR-21*:mirSVR_highEffct hsa-miR-21*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.46E-124 1.38E-120 2.53E-123 2.33E-122 302 1193 "CLK4,SYS1,NDRG3,CCDC85A,TMCC3,ADD3,PWWP2A,RNF150,NLGN4X,SLC44A5,ZNF608,MTUS1,KLHL13,PCDH19,SPOP,ALCAM,FAM135A,GPRASP2,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,EPB41L5,UPRT,PHYHD1,APP,SHTN1,AQP4,TMEFF1,ARNTL,LINC00173,CAPRIN2,ASPH,DDX3Y,RIPK1,ADGRB3,ARHGEF7,OSGIN2,CALM1,KALRN,CANX,VSTM2A,CH25H,RUNX1T1,PRC1,AIFM1,CD38,CDC27,CDC42,TBRG4,SOCS6,SYNPR,B4GALT6,RAB33A,NRXN3,PPT2,NMT2,STOML1,CLTC,CNN3,ARHGEF6,AKAP6,WHRN,SLC4A8,IGDCC3,CNRIP1,PREPL,SIPA1L1,VCAN,SOCS5,APPL1,PNPLA8,DOCK4,KCTD8,PABPC5,GIT2,SIRPA,DNAL1,DCC,DGCR5,ZEB2,MYEF2,ELMO1,LYPD1,SMG7,SPOCK3,SEC16A,DLG2,EXOG,DYNC1I1,PDCD6IP,DTNA,DTNB,ECM2,DYRK1A,ABCC9,AASDH,EBF1,EDNRA,FRY,RBM12,PHF20L1,ELAVL2,EMX2,OLIG2,LRRC17,SEZ6,CEP85L,ETV1,RTN3,DUSP27,RRAGB,SIRPB1,EYA1,F3,RPS6KC1,ACSL4,EFEMP1,FGF14,TMEM164,SMC2,UFM1,FAM49B,CELF1,STAU2,SARAF,AP4B1,NRG3,PHYHIPL,TRAF3IP2,GAD2,AHCYL1,GAP43,ZNF559,MYOZ2,TUBGCP4,MSTN,ARFIP1,CYP46A1,KIRREL3,GLS,TOX3,INSM2,GPD2,GPM6A,CCDC184,EML4,GRIA2,GRIA4,GRID1,GRM7,KAT7,AP4S1,RABL2A,RNFT2,ARHGAP36,HNMT,ZIC5,NME9,ITGAM,JAK2,SLC35G1,OLFM3,KIF5A,LAMP2,PAXBP1,SMAD1,MBNL1,AFDN,MN1,COMMD5,MSI1,MSR1,CTNNA3,MXI1,PABPC1L2A,CNOT4,SLC11A2,OCRL,PAX6,PCSK5,PDE4B,PDE4D,PENK,CDK14,ZDHHC8,PKD1,FTO,PLIN1,HMGCLL1,PDZRN4,TRHDE,PSAT1,MAGEL2,ING3,SEPT4,FAT3,PPP1R1A,CRLS1,PPP3CA,PPP3CB,VPS13C,SYTL2,SIDT1,OCIAD1,PTPRO,NKAIN1,TMEM255A,ZNF493,RDX,SLC6A15,ZYG11B,ZMAT4,RGS4,RGS12,TTLL7,RNF220,PBRM1,RNASEL,SETD5,TMLHE,CARF,ROBO2,PCMTD2,CCDC102B,BAALC,SPIN3,ADAL,RPS6KA2,CLIP1,SALL1,SEMA6D,LRRTM4,SLC30A10,CASC3,SGK1,ZFP30,ITSN1,DOCK10,MAGI3,FBXO11,SMARCE1,RCOR3,KIF13A,TMCC1,MYO16,DOP1A,SON,SP4,IDI2-AS1,TAB2,ITPRID2,ZNF302,ERBIN,ELOVL4,ADHFE1,KLHL7,SYNE2,VAMP1,COBL,CAMTA1,CAMSAP2,UNC5D,WWC1,DMXL2,TCF7L2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIRT1,DICER1-AS1,SLC44A1,TIAM1,TMPO,SYNPO2,TRIO,DCBLD1,CADM1,PITPNB,VLDLR,WIPF1,PCDH20,PLPP4,GPR158-AS1,SH3GLB2,WNK1,EMSY,STMN4,SCG2,NAV3,C12orf4,FAM13C,AMN1,FXR1,RNF146,SLC4A10" MicroRNA hsa-miR-193a-3p:mirSVR_lowEffct hsa-miR-193a-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.05E-124 2.27E-120 4.16E-123 3.83E-122 311 1267 "KCNH8,ACADM,ASIC1,ACHE,CLK4,NCKAP5,ADD1,SORCS1,PTCHD1,KIDINS220,SLC24A4,AP2A2,OSBPL8,DISP3,PCDH10,UNC79,CDC42BPA,ANK3,APC,VAT1L,BCAS1,TNRC6C,APP,CDK10,SEMA4G,PDXK,CASK,ZSCAN18,EIF4G3,DPY19L3,BCL2L2,SYNJ1,SYNJ2,JAZF1,C1QC,CAST,MTMR7,P2RX6,EVI5L,NOG,UBE2L6,CACNA2D2,CASC2,TAOK2,EPS15L1,NRXN3,KIAA1549L,CLTC,TJP2,ARHGEF6,AKAP6,SLC4A8,TOGARAM2,CHD1L,NCOR1,CS,FEZ1,CST3,PLXNA4,PPP1R16B,NRSN1,RUBCN,FAM131B,CX3CR1,ECE2,NOS1AP,FRMPD4,ARMCX2,RUSC2,GUCD1,MTX3,DOCK2,MAMLD1,DNAJB6,DYRK1A,ABCC5,EDN1,HEYL,RBM12,YAF2,GPR61,ABI2,GOLGA7,ASB3,EIF4G2,BSCL2,EN2,EPB41,ETV1,SIRPB1,ADGRV1,F5,ZIC4,SCML2,ZMYND10,FCGRT,TESK2,OLFM1,FHL1,SEMA6C,ANKFY1,PSD2,EFCAB2,NSG2,GABBR1,HBS1L,BRPF3,ZNF274,GAP43,ERAP1,ADAM28,CRCP,TCERG1,TNRC6A,STARD3,NUDT21,DIDO1,GRIA4,RFFL,GRIN2C,PRDM5,GRM7,LINC01089,FAM19A2,AP4S1,MAP4K5,MAEL,ZHX1,HMGB1,SMAP1,HTR5A,ICA1,MSL1,ZNF546,C5orf24,IL11RA,DIPK1A,INPP5B,ZNF385B,ITGAM,JAK2,KCNJ9,KCNJ10,KCNK3,KCNMA1,KIT,CAMK2N2,C2orf80,ASPRV1,CLEC18A,ZFYVE27,SYT9,IL17D,MGAT3,MMP16,ZNF680,CCDC80,RTL5,HNRNPM,NAP1L1,NCAM1,SLCO1C1,NNAT,NODAL,DNHD1,NRCAM,NUMA1,OGG1,OMG,OPHN1,PCDH9,PCSK2,PDE4D,PDGFRA,NALCN,CAMKV,CCSER2,NLE1,FAM216A,PLCB2,PLIN1,PNMA3,C11orf49,RETREG2,EPB41L4B,NXPH1,POU6F1,TATDN3,CCDC144B,PRKACB,PRKCZ,GRAMD1C,SLC22A23,TMEM104,PTCH1,PTK2,TMEM260,PTPRE,PTPRG,PTX3,PID1,CEP97,FAM66C,IQSEC3,ZYG11B,TRIM68,SLC25A36,PBRM1,RNASEL,RNH1,GSTCD,KIRREL1,ROBO2,EPHA10,ATP8B4,ACER3,TCP11L1,RTKN,CLIP1,SATB1,HOGA1,GALNT10,ITSN1,SHMT2,MAGI3,NLGN1,SEC31A,CLSTN1,ZNF365,RUFY2,KANSL3,LRRC55,YPEL4,ATF7IP,SORCS3,LIMCH1,PDZRN3,UNC80,DOP1A,SOX5,ZSWIM8,HECW1,UHRF1BP1L,TSPYL2,NPAS3,DDN,NFASC,TAB2,CLASP2,SS18,MAPK8IP3,ZSCAN29,SEPT8,KANK1,STXBP1,NSFL1C,FGD4,SYNE2,SYN1,TMEM150C,COBL,ATP11A,TAF6,EXOC7,CNTN2,TMEM136,SMG6,TBX15,VWA3A,EHBP1,TCF4,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,CRB1,TGFBR3,CDH22,MTMR14,TK2,LRRC8A,DAAM2,NPL,TPM2,ZNF346,AMACR,TRO,FNDC5,KCNE5,TSN,LRTM2,BCL2L13,VLDLR,CLIP2,CRB2,WNK1,NT5M,RGMA,CSDE1,PRDM8,RNF103,NAV3,URM1,DOCK8,KAT6A,FXR1" MicroRNA hsa-miR-367:mirSVR_highEffct hsa-miR-367:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.87E-124 2.74E-120 5.00E-123 4.60E-122 285 1064 "ABAT,SYN3,RBM10,NCKAP5,ACTN2,CSMD2,CSMD3,KLHL32,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,GPR158,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,PHF12,MIER1,ASPH,DDX3Y,ATP2A2,MTMR9,B3GALT2,NOL4,ADAM23,ADGRB3,MPDZ,BCHE,HCN2,CDK5R1,SYNJ1,CACNA1I,OSGIN2,KALRN,CAMK2A,VSTM2A,LDB2,MTMR7,AIFM1,CDC27,CDH10,SOCS6,CHM,NRXN3,HECTD1,NIPBL,TMEM155,AKAP5,CNRIP1,HS3ST5,FAM171B,CRHBP,SLC32A1,LRIG1,ATRNL1,VCAN,SOCS5,SLITRK5,ERC2,APPL1,EDRF1,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,G3BP2,CDON,CPEB2,PDCD6IP,ARRDC4,ABCC5,E2F5,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,TMEM74,HSPA12B,KIAA1109,POLK,ATP13A4,SLC37A3,TACC2,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,GABRA1,CHL1,IQGAP2,GAP43,ERAP1,GHR,GLYR1,PCDH11X,ZNF638,FERMT2,CNDP1,GPD2,GPM6A,LILRA1,GPR37,TPPP,GRIA1,DIDO1,GRIA4,RFFL,GRM1,PRDM5,GRM7,HAS2,UBE2QL1,MIER3,SCRG1,HNMT,MSL1,USP54,SLC6A17,ITGAV,C2CD4C,KIT,LAMP2,LIG4,LMO2,NCOA7,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MEIS1,AFDN,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NEUROD1,NF1,NOVA1,SMIM11A,CLDN11,P2RX7,GPR137C,PDE1A,GPR85,PIK3C2A,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,PLP1,PDZRN4,TRHDE,STRN3,SCHIP1,ING3,CRLS1,CEP41,GON4L,TMEM260,PTPRD,PTPRO,PEX5,TMEM255A,PLEKHB2,ENOX1,OXR1,RASGRF2,BSDC1,RDX,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,ELP2,RPE,RPE65,RPL15,FBXW7,BAALC,ABCA11P,AP1AR,SATB1,SCN3A,FAM19A1,FNIP1,HES6,CPEB3,MYO18A,FBXO11,CNKSR2,DZIP1,ZNF430,SLC12A2,TET1,CPEB4,ZKSCAN3,DMRTC1,CDK5RAP2,TTC17,SNRPN,PALLD,PDZD2,SOX11,MYCBP2,TEX2,IDI2-AS1,KIF1B,NPAS3,PBLD,ITPRID2,ELOVL4,RGL1,AJAP1,FGD4,PRRC2C,SYN2,SYPL1,SYT1,SYT4,CAMTA1,ANO4,DOCK9,SIK3,FAM200B,CRB1,HHIP,GALNT17,KCTD2,C5orf64,TPM1,TPM4,SYNPO2,TRIO,SGK3,UGT8,VLDLR,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,TRIM9,FMN2,ZSCAN26,PMEPA1,MAP3K12,MFF,CADM2,LRP8,EVI5,RNF103,NAV3,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,SLC4A10" MicroRNA hsa-miR-512-5p:mirSVR_lowEffct hsa-miR-512-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.80E-124 3.26E-120 5.94E-123 5.47E-122 368 1757 "SERPINA3,SDE2,CLK4,ACTN2,CSMD3,NDRG3,ADAR,SORCS1,ADORA2A,PWWP2A,ESYT2,KIDINS220,MTA3,PCDH19,WDR35,TXNDC16,CC2D2A,ZNF578,SEMA6A,SPOP,PCDH10,FAM135A,SYT13,FGD2,C6orf89,PHF12,MAGEE2,DGKZ,RASL11B,ALDH4A1,ATM,ATP2B3,B3GALT2,ATP6V0A1,BACH1,BARD1,LINC00847,SYNJ2,ARHGEF7,LURAP1,KALRN,CANX,VXN,VSTM2A,CAST,HIP1R,ISPD,KYAT1,CD81,CDC25B,MAGI1,DLGAP2,GPR37L1,MS4A7,NDST3,PPT2,CLCN4,NMT2,TJP2,QKI,NIPBL,AKAP7,LETMD1,ABI3BP,SMARCAL1,SEC31B,PREPL,ANKRD44,SNCAIP,LRRC3B,CSNK1G3,PDE4DIP,CNTNAP2,CST3,PHF14,CTH,CTNND1,DCAF4,USP6NL,CYBB,GPRASP1,ARHGAP32,GAPVD1,ARHGAP24,IST1,IP6K1,ARMCX4,DCC,PITPNC1,ZEB2,PLEKHM1,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,GSDME,DDX46,SMG7,SRGAP3,RABGAP1L,TMCC2,DMD,CDON,SLC12A6,ECM2,MAMLD1,DYRK1A,EDN1,SYT15,CNNM1,APH1A,MRO,ABI2,TENM1,EMX2,OLIG2,VPS13B,LRRC17,NCALD,MRPL10,CEND1,EZH1,TUBB3,RACK1,FCGR1A,TOMM40L,FGF12,FGFR1,CAMSAP1,UBE2E3,HPCAL4,FOXF2,IP6K2,SEMA4D,NELFCD,NBEA,ZCCHC17,POMT1,ZNF605,DACH2,GPR153,ADGRA1,DOT1L,OGA,GABBR1,HRASLS5,HBS1L,BRPF3,RAPGEF6,ARPP21,IP6K3,GATM,NFU1,PCDH17,PPARGC1A,LYVE1,DHRS4,BRD8,ZNF276,GLUL,PCDH11X,GNG4,ADGRA3,GPD2,PRUNE2,PRLHR,GRIK2,GRIK3,GRIN2C,GRM2,GRM7,LINC01089,PTPN5,ZBTB49,RABL2A,SOX21,GABARAPL2,SYNPO,HMGCL,HNMT,USP54,IL11RA,INSM1,TUBB2B,KCNC2,KCNJ3,KCNJ10,KCNK2,KCNN1,KCNN3,KIF5A,A1BG-AS1,CYP27C1,LSS,ZFYVE27,MAP2,MBD1,MDM4,MEIS1,MEST,SCAMP5,MID1,MN1,ZNF680,MSI1,ADAM22,BCO1,MT3,DDX25,MX1,MXI1,NEXMIF,ZNF862,HNRNPM,SFR1,NEK1,NFIX,NFYA,DNHD1,NUCB2,NUMA1,ZNF713,GLIPR1L2,CNTN3,PCDH9,PCSK5,PDE3B,ENPP2,PFKFB2,SEMA5B,NOMO2,PIK3R1,A2ML1,FAM216A,FXYD1,SMIM7,HMGCLL1,EPB41L4B,NXPH1,RASGEF1B,PKN2,GRAMD1C,HYDIN,PRPH,SIDT1,ANKHD1,UHRF1BP1,OCIAD1,PTPRO,RALGDS,TRIM68,RET,RFX5,ZDHHC4,RGS4,RNF220,RNASEL,ALG9,GSTCD,TMEM206,YY1AP1,ELP2,PCMTD2,MRAP2,NEK11,KIAA0895L,MCMBP,STK32B,RPS20,SYNDIG1,ZNF331,AP1AR,SMPD3,ITSN1,PPM1E,FUZ,SHC4,FBXO11,R3HDM2,WDR37,ZNF365,SLC6A8,KDM4D,SLC8A1,ARHGEF40,SLC12A2,SMARCD3,RCOR3,INAVA,SNAP25,SNRPN,TMCC1,FAM126B,DOP1A,SOX1,SOX2,ZSWIM8,IZUMO4,MYCBP2,ERC1,ZNF423,SPTAN1,MCF2L2,SPART,LMO3,TAB2,ZNF302,ZC4H2,LRRC4,APOM,CEP68,SYT4,CAMTA1,TAL1,UNC5D,EHBP1,TCF4,CLASP1,WDR7,DNAH7,CRB1,HHIP,ARL10,BHLHB9,BEX4,C5orf64,TNS1,RBFOX2,TPM1,C9orf85,METTL3,ANKRD20A2,CLHC1,AMOT,BCL2L13,MTCH1,CCDC136,CCDC14,WIPF1,RICTOR,GUSBP1,XRCC4,NDRG4,CRB2,TCEAL7,EML6,ANKS1B,SPIRE1,ZFAND5,UPF3A,INTS3,SLC30A4,PRDM2,STOX2,HPS4,VPS35L,TMEM163,ITM2C,WIPF2,PARP11,SMIM8,HNRNPA3,ST8SIA2,SLC4A10,LAS1L,PRRT4,SENP7,JPH3" MicroRNA hsa-miR-1229:mirSVR_lowEffct hsa-miR-1229:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.35E-124 3.57E-120 6.49E-123 5.97E-122 342 1528 "ABR,SYS1,KDM5D,NDRG3,PSMG3-AS1,ADD2,ADD3,SLC12A5,SORCS1,ADORA2A,KIDINS220,SYT13,ZFAT,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APBB2,GPAM,PHYHD1,LGR5,CDK10,CASK,CDK13,ASPH,TMEM108,ATP2B2,RNF182,CADM3,N4BP2L1,ATP6V0A1,ADAM23,ADAM15,SNAI3-AS1,BBS2,MPDZ,BCL7A,DCAF5,CFLAR,LINC00906,AP1M1,BSN,CA12,DIRAS1,CAMK2D,VXN,CAST,CBLN1,METTL6,CCNH,MTMR7,SLC16A4,CBFA2T2,DGKI,CDC27,LGI1,LOC730101,IGFN1,CRLF1,CACNA2D2,CHM,CHRNA4,NRXN3,IGFBP7-AS1,PPT2,COG1,C4orf33,SULT4A1,MAP4K4,CNN3,AKAP7,COL9A1,SLC4A8,ACBD5,CDC42BPB,CREM,RBM39,GDA,CSF2RA,FEZ2,ARHGEF10,VCAN,PDE4DIP,FAM169A,GREB1,DCAF4,CCDC144A,CYBB,ARHGAP24,FRMPD4,KIAA0513,ZNF337,RASSF2,KIAA0586,DGKG,TOMM20,ZEB2,HEPH,CNIH3,BLOC1S6,SMG7,SNAP91,SV2A,SGSM2,FAM107B,DLG2,DLG3,ATN1,FAM135B,SYT15,KLHL5,RBM12,GPR61,ABI2,SORBS3,ELAVL2,MRNIP,EML1,EMX2,CDHR1,PTK2B,TUBB3,CORO2B,TOMM40L,ZSCAN30,FGF12,FGFR1,AMOTL2,PCYOX1,SYNCRIP,SEMA6C,SEMA4D,SYT3,PDLIM5,ZNF605,SARAF,TMEM151A,TBR1,NEURL4,MEGF10,ARPP21,GALR1,SALL3,ZNF274,SEPT9,CPLX2,KIAA1841,GCNT2,NTNG2,TXNL4A,ZNF638,DCLK2,GPT2,FUT10,GPR37,GRIA2,PLCD4,GRID1,GRIK3,GRIN2C,ATE1,LINGO1,TMEM179,FAM222A,MAN1B1,SYNPO,HNF4G,ZDHHC15,ZNF546,C2orf72,C5orf24,IGSF1,SCIN,IL6R,ITGA7,SLC35G1,KCNA1,KCNJ10,KIT,FGFBP3,PIK3AP1,MAN2A2,ZFYVE27,MAP6,MAPT,SYT9,CHST6,IL17D,LDLRAD3,ZNF92,DDX25,NAP1L2,FXYD6,NEUROD2,NF1,HCN1,NTRK2,NUMA1,OPA1,OPCML,KCNK10,SNTG1,PDCD2,PDE1C,PDE2A,PDE3B,PDE4D,PFKFB4,CDK14,TMIE,ANLN,PCDH18,SDK2,SH3KBP1,POU3F2,TMEM235,CRLS1,PPP2R5E,NKAIN4,MAPK9,DIRAS2,BCAS3,SIDT1,UHRF1BP1,NCR3LG1,PTPN13,PTPRB,OCIAD1,PTPRG,C1orf109,NKAIN1,RAB5B,SLC25A48,SH3TC2,ATG16L1,RASGRF2,RFX3,PRIMA1,ARHGEF10L,SEC61A2,RNASEL,LGI2,ARMC5,CARF,KIRREL1,YY1AP1,ELP2,GLDN,ADAL,KCNIP3,KCNIP2,CLIP1,RTN1,FAM182A,FAM192A,ATXN7,LINC00461,ASRGL1,MRAS,ITSN1,NTNG1,AMBRA1,FBXO11,ST6GAL1,SLA,RUFY2,SLC6A7,SLCO1A2,RIMS1,MBD5,SNRPN,TNIK,ZSWIM8,KDM4C,UNC5B,SPART,NFASC,C11orf87,COLGALT2,SMOC1,LRRC4,ELOVL4,CEP68,DIP2A,STXBP1,AJAP1,RHBDL3,SYP,SYT4,ATP11A,CAMTA1,PDLIM2,WWC1,VWA3A,WDR7,SYNE1,OBSL1,PUM2,ARHGAP9,TF,CHST8,ZNF106,FBXL16,GZF1,TMOD1,FAM124A,SEZ6L,TPD52L2,CDK20,SYNPO2,TRIO,KCNE5,ANO5,TTTY15,HEPACAM,WIPF1,SLC13A3,ZNF24,TRIM9,FMN2,ZNF74,NDRG4,LYPD6,POLR3H,AMZ1,PCBP1-AS1,MEIS3,WNK1,LRP8,RNF103,PCDH15,WNK3,SLC17A6,GOPC,FZD3,PAK5,SMIM8,HNRNPA3,JMJD1C,TIGD6,TTC7A,NETO2,SOCS4" MicroRNA hsa-miR-1914*:mirSVR_lowEffct hsa-miR-1914*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.41E-124 4.72E-120 8.57E-123 7.89E-122 338 1495 "DPF1,TTYH1,ASPHD1,ASIC2,ASIC1,ACTN1,GPRIN1,ADAR,GALNT13,RNF157,ERMN,PLEKHH1,ADRA1B,ZNF608,SNX32,AK2,PLA2G6,ALAD,GOLGA7B,LRFN1,ANK1,MYH7B,CNIH2,UPRT,GPAM,FAM131A,PHYHD1,APOC1,CACHD1,PPFIA3,CPNE5,AQP4,SEMA4G,ZFYVE28,CDK13,DACT3,ATP1A3,ATP2B1,DPY19L3,MYOM1,BCL2L2,KSR1,BMPR1B,GPC2,CDK5R2,CABP7,CALM1,TRIM41,BRSK2,METTL6,USP2,ENTPD2,FOXN3,PLEKHB1,FAM189A2,FADS2,MAP4K4,IGLON5,CNTN1,COL9A2,COL11A2,CHD1L,ZNF385A,CLOCK,NCOR2,TRIM69,DZIP3,KIAA0040,PNPLA8,ARHGEF4,CTNND2,RUBCN,HDAC9,ARHGAP32,KATNAL2,CENPL,EARS2,TM9SF4,IST1,GIT2,DBN1,PITPNC1,SPATA2,SV2B,TMCC2,DNAH9,CD99L2,RPS6KL1,DMTF1,SLC25A18,ACOT8,SEZ6L2,EDN1,ABI2,EGR3,EMX2,ENO2,EPB41L2,DENND4A,MRPL37,ETV1,ANKMY1,ECSIT,F5,ZIC4,TUBB4A,CHST15,KAT8,PPP1R1B,CAMSAP1,SUCO,PCYOX1,EVL,NELFCD,DCTN2,CGREF1,PHYHIPL,NEURL4,IQGAP2,DISC1,KIAA1841,GCNT2,SRCAP,MSTN,CYP46A1,GHR,GK,TTBK1,TCERG1,GOLGB1,CCDC184,NUDT21,EML4,GRIA1,ADAMTS8,GRIN2C,KAT7,ZBTB49,LINC01551,RABL2A,FRMD5,PTGDR2,MAN1B1,HRH3,ATXN2L,ARHGAP36,ELOVL5,HMGB1,AGBL5,TLX1,HSPA1L,FAM95B1,LRRCC1,DISP2,SCRT2,INPP5B,KCNK2,KCNK3,LAMP2,LMO1,LSS,GPR155,ZFYVE27,MAPT,MBP,SHC3,MGAT3,MITF,COL28A1,MSI1,PTOV1,MT3,RSPO2,MYO7A,NEFH,NEUROD2,OTOGL,VWA2,NOVA2,DNHD1,PCBP3,NRGN,NTRK2,P2RY1,PAK3,CDK18,PDPK1,GNG2,GDAP1L1,TMIE,NOMO2,ZNF655,PLCB2,FTO,PLTP,PLXNB1,PRRX1,NECAB2,TNPO2,C19orf57,SLC26A11,MASP1,SIDT1,CNTLN,PTAFR,TMEM231,RALGDS,RASGRF1,RGS12,RNASE1,RPRD1A,SETD5,CYB561D1,KIRREL1,SNX22,KIAA0895L,ACER3,TCP11L1,MEG3,HSD11B1L,CLIP1,STX1B,SEMA6D,SCP2,SEC14L1,FOXRED1,MRAS,ITSN1,CPEB3,CHD9,FHOD3,ST6GAL1,BCAN,SLA,PPP4R3A,SMTN,FAM214B,PKNOX2,SLC6A8,YPEL4,SLC8A1,ARHGEF40,SLC11A1,SLC12A2,SLIT1,SMARCA4,SMARCD3,ANKRD36,UNC80,SON,WDTC1,TNIK,ZCCHC24,CAND2,ERC1,ZC3H13,MCF2L2,NFASC,C11orf87,COLGALT2,SSTR1,SSTR2,NCDN,MAPK8IP3,DIP2A,STXBP1,GSE1,JMJD6,SYN1,SYP,CAMTA1,MLST8,TAL1,UNC5D,WWC1,ATMIN,VWC2,TCF7,ZEB1,TPCN2,DOCK9,PHF24,NSD1,AHCYL2,HIF3A,RNF216P1,DICER1,FBXL16,THRA,NR2E1,RIMBP2,PRRT1,CABIN1,SEZ6L,TPM1,TPM2,C9orf85,TPM4,RGMB,ZNF346,PPIL6,NTSR2,DCBLD1,TMPRSS5,TSN,SSBP2,TTTY15,HIRA,FAM181B,MTCH1,VIPR2,VLDLR,BEST1,CLIP2,PORCN,ZNF70,NDRG4,SLC26A10,CELF4,ZBTB38,ANKS1B,SH3GLB2,RGMA,PCDH15,GAL3ST3,MVB12B,PARP11,ST7,UBE3B,HNRNPA3,PHTF2,CAMK1G,TRAM2-AS1,RNF170,VANGL2,ADAMTS10,DPF3,LAS1L" MicroRNA hsa-miR-607:PITA hsa-miR-607:PITA_TOP PITA 1.26E-123 7.10E-120 1.29E-122 1.18E-121 267 934 "CSMD2,XKR4,SLC25A25,KLHL32,ADD3,CDC7,ERMN,PTCHD1,NLGN4X,ZNF608,GPR158,PCDH19,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,GPAM,API5,CDC14B,ZFYVE28,ZBTB10,NCOA1,DDX3Y,MTMR9,BLM,CDK5R1,SYNJ1,MTMR3,WASF1,LDLRAD4,CACNA1A,PTBP2,CLDN10,KRIT1,ARHGEF2,LONRF2,CLGN,CFL2,SRSF11,CNOT8,SLIT2,KMT2C,NRXN1,NMT2,CLTC,QKI,NIPBL,CNR1,CNTFR,ZNF521,CREM,CREB5,HAPLN1,ANKRD44,CLIP3,FEZ2,LRRC3B,CSNK1E,PHACTR3,SLITRK5,ERC2,APPL1,CTNND2,RIMS2,ST18,KIAA0408,TOX,KIF26A,IST1,DBT,JAKMIP2,MYEF2,FBXL5,ZC3H11A,DDX46,RHOBTB1,SPOCK3,DMD,DYNC1I1,NR1D2,DPYSL2,PDCD6IP,MAMLD1,GOLT1B,FAM135B,FRY,RBM12,YAF2,EFNB3,MBNL2,EIF4G2,TENM1,ELAVL2,PLEKHA1,EPB41L2,GPHN,EPS8,ERBB4,EXTL2,KATNAL1,FABP7,ATP8A1,MED12L,KIAA1109,SUCO,MEX3B,FOXO3,CELF1,FUT9,GABRA4,CHL1,RAPGEF6,NEK6,NCKAP1,IQGAP2,MYOZ2,MSTN,PCDH17,TCERG1,SPIN1,TNRC6A,GNAO1,GNG3,PRRC2B,GPM6A,FUT10,GPR34,GPR37,PCLO,GRIA2,CIT,FAM19A2,PSIP1,ATG4C,KLF12,MIER3,NEGR1,IGF1,RBPJ,KIF2A,KIF5C,MARK1,SYT9,LDLRAD3,MEIS1,AFDN,MN1,MSI1,HS6ST3,NEXMIF,HNRNPM,NAP1L1,NCAM2,ZC3H12B,NFIA,OPA1,PRTG,PDE3A,PDE4D,ENPP2,PDPK1,GNG2,CCSER2,HMGCLL1,PURG,MAPKAP1,FAT3,PPP2R5E,MAPK10,TMEM260,PTPRD,ARID4A,RBBP6,SLC6A15,FIGN,PBRM1,ZFHX4,ZNF532,SETD5,ROBO1,ATP8B4,CLIP1,NCBP3,AP1AR,ATXN1,FAM19A1,SFPQ,KIF21A,PPP1R9A,DOCK10,CHD9,FBXO11,FNDC3A,NLGN1,SLC1A2,SLC1A3,BTBD3,SEPHS1,SLC8A1,TRIM67,SLC12A2,NAPB,COA1,FAIM2,PDZRN3,MYT1L,SOX2,SOX3,SOX10,DOK5,ZHX3,SP4,PEG10,ZNF423,ARHGAP26,LMO3,CLASP2,LARP4,LRRC4,ERBIN,ELOVL4,ACSBG1,PRRC2C,PLCB1,SYN2,SYPL1,CAMTA1,CAMSAP2,UNC5D,TCF4,SATB2,TCF12,ARHGEF12,FRYL,DICER1,AP4E1,SLC44A1,TJP1,DDHD1,ZFP91,RIMBP2,SYNPO2,STXBP4,TRPS1,TMEFF2,FLRT2,USP1,BEST1,TBC1D15,WIPF1,XPO1,ZIC2,ZIC3,ZNF711,KCNT2,REEP1,SMARCAD1,PCDH15,SLC17A7,FAM13C,HNRNPA3,PHTF2,CERS6,MSRB3,ST8SIA2,SLC4A10" MicroRNA hsa-miR-517*:mirSVR_lowEffct hsa-miR-517*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-123 9.04E-120 1.64E-122 1.51E-121 332 1447 "ACADM,NCKAP5,CSMD3,NDRG3,GALNT16,ADCY2,CCDC85A,TMCC3,GALNT13,ADD1,USP31,FAHD2CP,PCDH19,PLA2G6,ALAD,AMPD2,ZFAT,CDC42BPA,DPP10,ANXA7,APBB1,APBB2,UPRT,GPAM,ALS2,FAM131A,TNRC6C,TMEFF1,SPTBN4,ASPH,NCOA1,NUMB,ASTN1,STX16,CADM3,N4BP2L1,NOL4,DPY19L3,ADGRB3,BCL2L2,BCL7A,DCAF5,BTK,CASTOR3,CFAP410,CACNA1D,CALM1,KALRN,CAST,SPAG9,SHISA7,KYAT1,MTMR7,CDC42,NOG,UBE2L6,CHM,JAM2,NDST3,LHX2,SRP14-AS1,MAP4K4,TMEM155,SLC25A27,SLC4A8,ZFP28,RBM39,AKAP12,MICAL2,ATRNL1,RIMS2,DCAF4,CCDC144A,BOC,ARHGAP32,GAPVD1,FRMPD4,TOX,ZFYVE16,LIN54,PHYHIP,DAPK1,ZEB2,HEPH,PLPPR4,WDR20,FAM107B,RAB39B,DMD,USP3,DYNC1I1,DMTF1,SLC12A6,CASP8AP2,PDCD6IP,EDN1,HIPK3,KLHL5,FRY,PHF20L1,EGFR,ABI2,TENM1,PAN3,EIF1,RAB9B,EPS8,ZNF549,GMPR2,MRVI1,ABCA8,AMZ2,SH3YL1,TOMM40L,ZNF589,FECH,FGF1,FHL1,MEX3B,SEC23B,COQ5,SORBS1,STAU2,GABRA2,GABRA3,ZNF44,GALNT15,TRAF3IP2,GAD2,AHCYL1,GALC,IQGAP2,SIGLEC8,MTHFD2,SULT1C4,CSDC2,PPARGC1A,MALT1,KIRREL3,GLS,PCDH11X,MAP7D2,INSM2,GPD2,FUT10,STON1,CLASRP,FAM19A2,PSIP1,ATOH8,GYG1,IRAK3,RASSF8,SYNPO,HTR2A,C2orf72,IGFBP1,NME9,KIT,LIG4,HECTD2,ARHGAP12,NCOA7,MAN2A2,MAP2,MBNL1,MBP,CHIC1,KITLG,SAMD5,ADAM22,MYO5A,MYT1,NBL1,NF1,SLCO1C1,NOVA1,PCBP3,OCRL,CHAMP1,OPA1,OPCML,GPR137C,PAX6,PDE4D,PDGFRA,PENK,SSH1,TMIE,CCSER2,SNX10,PLIN1,SCHIP1,ING3,PPP2R5E,GRAMD1C,DIRAS2,GDPD1,PLPPR1,TMEM260,STK32A,PTPN13,PTPRN,STRC,PPP2R3C,PLEKHB2,RAD51D,RAP1GDS1,RASGRF1,SLC6A15,ZYG11B,GTDC1,TTLL7,RPRD1A,CCDC82,DCUN1D2,TMLHE,MRAP2,ADAL,ACER3,TCP11L1,ST6GALNAC6,CLIP1,STX1B,NCBP3,DGLUCY,SARS,TNFRSF19,SEC14L1,SOX6,CASC3,ZFP30,FBXO11,SLITRK3,NLGN1,SLC1A3,PPP4R3A,SLC6A11,SEPHS1,CCDC88A,SLC15A2,MTERF2,BTBD7,CPEB4,CDK5RAP2,SMARCD3,RIMS1,MBD5,CMTR2,TMCC1,FAM126B,MYO16,WDTC1,TNIK,SOX5,ENKUR,UNC5B,ZC3H13,NFASC,ATP10B,COLGALT2,THSD1,ZC4H2,MAPK8IP3,NEK4,CEP68,KLHL7,PRRC2C,SYT1,TACC1,CAMSAP2,ADGRL3,KLHL4,TCF4,DMXL2,RPGRIP1L,TCF12,WASHC4,PCDHGB7,PUM2,PCDHA5,FRYL,SIRT1,ITGB3BP,TGFBR3,ZNF106,ACTR6,ERCC6L2,FAM124A,KAT6B,RGMB,ZNF346,SYNPO2,SMUG1,STXBP4,PPIL6,FNDC5,ANKRD20A2,TSC1,TTPA,ZKSCAN5,SLAIN1,VLDLR,LAT2,NSD2,RICTOR,PCDH20,ZNF23,FMN2,ZNF138,ZBTB38,ANKS1B,PLPPR5,SYNC,WNK1,PRDM2,GDPD5,LMAN2L,ADAMTS9,HPS4,NAV3,SNX27,LINC00632,FAM47E,WIPF2,EPM2A,RGS7BP,UBE3B,PAK5,FBXO36,TIGD6,GAN" MicroRNA hsa-miR-4268:mirSVR_lowEffct hsa-miR-4268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-123 1.01E-119 1.82E-122 1.68E-121 363 1718 "TTYH1,SDE2,ABAT,DGCR6,KCNH8,NCKAP5,ARID1A,ADCY6,ADD1,GRAMD1B,ADORA1,PTCHD1,OSBPL6,WDR35,ARHGAP20,CARNS1,BEGAIN,AMPD2,AMPD3,EP400,PPFIA1,CNTNAP1,DGKZ,UPRT,ALS2,NT5C3B,PHYHD1,PPFIA3,ASGR1,ATP1A3,SLC4A4,CADM3,ADAM15,AZGP1,BCHE,BCL2L2,DNAJC27-AS1,CFLAR,DST,SYNJ2,MYRF,CA4,SYT6,CAST,BRSK2,HIP1R,CBR1,CLDN10,CCNT1,AIFM1,CBFA2T2,DGKI,CDH10,CDH18,LOC730101,ASIC3,CASC2,TAOK2,KIAA1549L,NRXN2,SLC24A2,SRP14-AS1,ARHGEF6,CNTFR,CNTN1,IQCK,PCYT1B,ARMC8,CABP1,SLC25A27,SUMF2,BTF3L4,LETMD1,MYRIP,IGDCC3,MFSD4A,CHD1L,CRMP1,CLIP3,CSF1,CSF1R,ARHGEF10,APPL1,PHF14,CTNND1,NRSN1,ECE2,PHF19,EARS2,DAPK1,TOMM20,DNAJC6,B3GAT3,RUSC2,C2CD2L,KIAA0319,DDX46,SV2B,SRGAP3,GRIN3A,DNM1,NYAP1,NR1D2,DOCK2,DMTF1,RCAN1,DTNB,TOM1,MAMLD1,DNM1L,E2F6,HIPK3,EFNB3,FAM13A,SORBS3,C8orf37,SEZ6,EPHA5,EPHB1,ENPP6,RASL12,SIRPB1,ZNF461,TBC1D16,TMEM132C,PTK2B,FCGRT,STRADA,TESK2,FECH,MED12L,AMOTL2,SUCO,MEX3B,FLT1,NOP56,WDR83,SPECC1,PDLIM5,NSG2,CELF1,DACH2,CGREF1,ADGRA1,DOT1L,NRG3,OGA,NEURL4,GALNT15,GABRG1,GAD1,RAPGEF6,GAP43,ALDH1L1,GCNT2,GDF9,GFER,DHRS4,RND1,CRCP,GLI2,RAB30,ZNF638,INSM2,GNAO1,PSRC1,PRUNE2,CCDC184,STON1,TMEM121B,PCLO,STMN2,GRIA1,C1QL4,RFFL,GRM1,GRM2,GSTM5,MFSD2A,RNFT2,ADAMTS6,TNFAIP8L3,HNMT,TLX1,CPT1C,HSF2,SMAP1,ICA1,EID2B,SOWAHA,DISP2,PLD5,KCNC1,KCNC2,KCNH2,KCNJ11,A1BG-AS1,LRRC4B,LSS,MAG,MEIS1,MEIS2,MGAT3,AFDN,MN1,ZNF680,SCG3,MTR,HS6ST3,MYO7A,ZNF862,NBL1,NFYA,NNAT,NUMA1,OGDH,PAH,PAK3,PBX1,PCMT1,PCSK5,PDCD2,PDE1A,PFKFB3,DUSP26,GDAP1L1,TMIE,FAM218A,PLCB2,PLCL1,PLP1,SLC25A23,PRIMPOL,ING3,DRAM2,POU6F1,PPARA,PTPA,PPP3CB,NKAIN4,PRKCZ,MAPK3,MAPK4,MAPK10,WBP1L,LAMA1,DEF8,PSMD13,ZIK1,CASTOR1,PTPRG,PTPRO,NKAIN1,PID1,RAD51D,NWD1,OXR1,RASGRF2,ZDHHC14,KCTD17,RIC8B,MYH14,ARMC5,ELP2,SPIN3,MAP6D1,HSD11B1L,ATAT1,ZNF331,SCG5,ZFP30,ITSN1,FAM102A,FERMT1,FNDC3A,NLGN1,SEC31A,NUBPL,PAAF1,RPH3A,SMTN,SLC6A1,LRRC55,SLC6A8,SLC8A3,CCDC88A,SLC9A5,SLC12A2,ZNF334,BTBD7,SMARCD3,SNRPN,USP33,MYT1L,BDP1,SOX10,SP2,ZSWIM8,CLUAP1,KIF1B,IQSEC2,TSPYL2,SPART,ITPRID2,SSPO,DIP2A,PHLDB1,SYN2,SYT1,MTCL1,SEMA4A,FAM208A,TBCEL,VWA3A,TCEA1,USP22,WDR7,USP32P1,TNS2,HIF3A,ITGB3BP,LEFTY2,SLC44A1,HEY1,ASXL3,DDHD1,RIMBP2,RBFOX2,TPM3,TRPS1,TMPRSS5,TTPA,UBE2H,UBE3A,PITPNB,NSD2,NPDC1,RICTOR,XRCC4,ZFP41,ZNF142,ZBTB16,ZNF154,REEP1,UPF3A,WNK1,CA10,SLC30A4,PRDM2,CSDE1,LMAN2L,SEMA3B,KCNAB1,FIP1L1,TRIM16L,C12orf4,PDSS2,RGS7BP,MARCH8,FBXO36,NUP214,VANGL2,SOCS4" MicroRNA hsa-miR-202:mirSVR_lowEffct hsa-miR-202:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-123 1.28E-119 2.30E-122 2.12E-121 315 1307 "ACADM,ASIC1,CLK4,ARID1A,ADAR,ADARB2,DSCAML1,ADRB2,DPY19L2P4,NLGN4X,ZNF608,MTUS1,GPR158,CASKIN1,PCDH19,RTL9,OSBPL1A,CEP126,FAM135A,OGT,DPP10,USP28,PPFIA1,APAF1,EPB41L5,BCAS1,ASGR1,ZNF583,MTMR9,B3GALT2,DNAJC27-AS1,NRP2,DST,NAE1,MTMR2,JAZF1,CACNB2,MAP7,CLDN10,CD86,REPS2,LRRFIP1,CLGN,FOXN3,CHN2,ARHGAP22,NRXN3,IGFBP7-AS1,C4orf33,NIPBL,CNTN1,FAM149A,SUMF2,BTF3L4,COL9A3,AHCTF1,MYRIP,ZFP28,MFSD4A,SEC31B,ABCG1,MICAL2,CSNK1E,IPCEF1,CST3,KIAA0040,CFAP61,KATNAL2,DCAF8,PABPC5,ARMCX4,PITPNC1,ZEB2,RUSC2,DMTF1,DPH1,DPP6,DUSP9,DNAJB6,ABCC9,E2F5,EFNB3,EIF4G2,TENM1,PLEKHA1,ELAVL4,COQ7,LRRC17,EPHB1,KCNMB2,IGSF6,ZNF549,NRN1,WAC,SH3YL1,ACSL4,TOMM40L,ZSCAN30,GORAB,FER,KIAA1109,FOXG1,RGPD5,SGIP1,EFCAB2,HVCN1,USP16,APOPT1,AP4B1,TVP23A,PHYHIPL,HRASLS5,GALC,MTHFD2,GATM,ARFIP1,LYVE1,BRD8,RNPS1,GLI2,GLRB,GLS,TNRC6A,KDM2B,OS9,LNX1,FUT10,EML4,RAPGEF4,GRID1,GRIK2,GRIK3,ADAMTS8,PRDM5,ZNF496,CIT,RNF165,FICD,ARHGAP19,DDX19B,MIER3,ELOVL5,SYNPO,HMGCL,HNF4G,NEGR1,OPALIN,DHX35,HSD17B1,LRRC75A,CELF5,C2orf72,SOWAHA,RBPJ,PLD5,IL6R,IL11RA,INSM1,TUBB2B,LRRTM3,METTL21A,KCNB1,KCNJ10,KHK,PAXBP1,NCOA7,LSS,SMAD1,MAN2A2,MAP2,ADAM11,LDLRAD3,MDM4,LRP1B,MEF2C,MEST,KCTD6,MN1,SAMD5,ADAM22,MSR1,NRBP2,MTR,NEFM,NME4,NTRK2,NTRK3,GPR88,PCDH9,PRTG,ZDHHC8,ABCB1,ANLN,ZNF655,SNX10,RETREG1,ST8SIA5,PLP1,PDZRN4,PMP22,LRP12,ING3,DRAM2,PPP2R5E,RANBP3L,PRKAB2,RAB39A,PKN2,MAPK9,PRPSAP2,RELN,UHRF1BP1,NCR3LG1,FAM120C,PTPRZ1,RAD52,ZNF793,ATG16L1,RBBP8,SLC6A15,DPF2,ERI2,GTDC1,FIGN,TTLL7,RIT2,SEC61A2,ZFHX4,ARMC5,RORB,ADAL,LGR4,PTGR2,MEG3,RTKN,KCNIP2,CLIP1,RYR3,TRAPPC13,SEMA6D,ATXN7,SEC14L1,GALNT10,SCAF8,ITSN1,KIF16B,FNDC3A,CNKSR2,SEC31A,ANKRD6,URGCP,BTBD3,WDR47,BTBD7,ATF7IP,CDK5RAP2,RIMS1,MBD5,DOP1A,SOX11,KDM3A,KDM4C,IQSEC2,C11orf87,CLASP2,CLSTN2,POGZ,SSPO,NXT2,STAU1,FGD4,DNMBP,FAM208A,SMG6,ACSL6,TCF4,TPCN2,FAM189A1,PCDHB6,TGFBR3,SLC44A1,TJP1,BHLHB9,KCTD2,R3HDM1,KAT6B,PIK3R5,NPL,RUNDC3B,TRO,TSC1,ANO5,RFTN2,PRR18,CLHC1,HEPACAM,PITPNB,VSNL1,ZNF781,PCDH20,CELF4,EMSY,PRDM2,STOX2,RNF103,PCDH15,SNX27,FAM47E,UBE3B,KAT6A,RNF170,FXR1,AP3B2,GAN,PRRT4" MicroRNA hsa-miR-944:PITA hsa-miR-944:PITA_TOP PITA 2.35E-123 1.32E-119 2.37E-122 2.19E-121 270 958 "RALGAPA1,KLHL32,AXIN2,SLC12A5,ERMN,USP31,PTCHD1,ZNF608,INTS2,GPR158,HECW2,HFM1,SEMA6A,SPOP,BCAR3,FAM135A,LRCH2,ANK3,MAP4K3,APBB2,APC,GPAM,SHTN1,CDC14B,TMEM263,TMEFF1,ARHGAP5,CDK13,STK33,NCOA1,ASTN1,ATP2B1,ATP2B2,ATP2B3,BCL2L2,CACNB4,KALRN,CAMK2G,MAP7,RUNX1T1,USP6,SCARB1,TMEM257,LRBA,DCLK1,MAGI1,CDO1,CFL2,FOXN3,SYNPR,LHX2,QKI,NIPBL,AKAP6,AKAP5,SLC4A7,TBPL1,AHCTF1,SLC35F1,CREB5,SUSD5,DZIP3,PPP1R16B,APPL1,PNPLA8,ST18,ZFYVE16,PABPC5,MYEF2,TIAM2,ZC3H11A,SV2B,DLG2,RAB39B,DMD,USP3,CPEB2,CASP8AP2,DPYSL2,DRD1,ATN1,DNAJB6,DYRK1A,ST8SIA3,CNNM1,YAF2,GPR61,MBNL2,KMT5B,EIF4G2,TENM1,ELAVL3,RGS17,PAN3,EMX2,EN2,EPB41L1,SRRM1,EYA1,NRN1,ACSL4,ZIC4,KIAA1109,JKAMP,SORBS1,FUT9,TBR1,PHYHIPL,STAG2,MEGF10,GAB1,ERAP1,SRRM4,WASF3,GATM,MSTN,ARFIP1,SESN1,PCDH17,GHR,PPARGC1A,GK,SPIN1,DCLK2,CECR2,RAPGEF4,GRIA2,GRIA4,GRM7,LINGO1,ZHX1,FRMD5,KLF12,MIER3,HMGB1,GABARAPL2,HNF4G,HPCA,NEGR1,ICA1,NKD1,SCRT2,ITGAV,KCND2,KCNK2,KIF5C,KTN1,SMAD1,GPR155,MATN3,CHIC1,LRP1B,MID1,MITF,MKLN1,ERICH3,MXI1,ZC3H12B,NEFM,NEUROD1,NF1,NOVA1,OPCML,PCSK2,PDPK1,PMP2,PMP22,TRHDE,PRRX1,RETREG2,EPB41L4B,FAT3,LRRN3,PPP3CA,PRKAB2,PKIA,PKN2,CNTLN,PTCH1,TMEM260,ZSCAN32,PTPRB,PTPRO,PTX3,SH3TC2,OXR1,ARID4A,RADX,KHDRBS2,SLC6A15,FIGN,ZFHX4,SETD5,ZC3H14,MCMBP,LGR4,HUNK,CLIP1,RTN1,SATB1,SOX6,SCAF8,PPP1R9A,KIF16B,CPEB3,CHD9,ST6GAL1,NLGN1,SEPHS1,SLC8A3,CCDC88A,SLC12A2,CPEB4,SORCS3,PALLD,TRERF1,SOX11,SP4,PEG10,CDK19,NPAS3,LARP4,ERBIN,STXBP1,SYT11,PLCB1,TAC1,CAMSAP2,SIN3B,TRIM2,RPGRIP1L,WASHC4,DICER1,ZFPM2,AP4E1,HHIP,SLC44A1,TLL2,HEY2,CSMD1,TRPS1,SSBP2,RFTN2,HIRA,FAM155A,PITPNB,TBC1D15,MICU3,KCNT2,MKRN3,LYPD6,ZBTB38,TMEM237,ZFAND5,LRP8,SLC38A1,PRDM8,NAV3,PDSS2,FZD3,PHTF2,CERS6,JMJD1C,MSRB3,SSPN,NETO2,SOCS4,ST8SIA2,SLC4A10,SENP7" MicroRNA hsa-miR-154*:mirSVR_lowEffct hsa-miR-154*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.75E-123 2.11E-119 3.78E-122 3.48E-121 352 1624 "KCNH8,ACADM,SYS1,ARID1A,FMNL2,PSMG3-AS1,ADD2,PLEKHH1,ADORA3,MTUS1,KCTD16,KIAA1324,TAOK1,LRRC7,ALAD,SPARCL1,ALCAM,BCAR3,AMPD3,DPP10,LRCH2,ANK3,MAP4K3,CNIH2,PKP4,APAF1,APC,UPRT,GPAM,CACHD1,SHTN1,AQP4,ASPH,NCOA1,NUMB,DDX3Y,TMEM108,ATP2A2,ADGRB3,MIR9-3HG,DST,SCAPER,MTMR2,IL33,CACNB2,KALRN,SLC25A14,PRC1,MTMR7,SLC16A4,SEPT7,CDC42,MAGI1,CDO1,FOXN3,CHGA,CHN2,B4GALT6,ZBED5,NDST3,KMT2C,RAB33A,CLCN3,C4orf33,QKI,NIPBL,AKAP7,AKAP6,COL4A5,LETMD1,ACBD5,ZNF521,MFSD4A,CLOCK,CS,PDE4DIP,SLITRK5,CTNND2,PUM1,ZSCAN23,CCDC144A,GPRASP1,ARHGAP32,RIPOR2,PHF19,ZNF337,MAML1,HEPH,CNIH3,KIAA0753,CEP170,DDX46,SNAP91,RABGAP1L,ZNF582-AS1,CHRDL1,DLG2,DLX1,GRIN3A,DMTF1,CASP8AP2,DSCAM,ECM2,EDNRB,ATL1,SEMA3D,FSD1L,OPTN,GPR61,MBNL2,ABI2,EGR3,ASB3,EIF4G2,TENM1,EPB41L2,LRRC23,KCNMB2,SRRM1,DENND4A,CEP85L,TMEM74,ETV1,CLVS1,NSRP1,FAM198B,WAC,ZNF585B,RPS6KC1,FDFT1,SEC24B,FER,MED12L,FGF12,FGF13,UBE2E3,IP6K2,SYNCRIP,FOXO3,TPK1,CAMKK2,DACH2,ST6GALNAC3,FYB1,ZMAT1,STAG2,MEGF10,CHL1,GABRG1,GABRG2,FAM184B,HBS1L,C15orf41,DISC1,CPLX2,DNER,MMADHC,USP19,GHR,SPIN1,TOX3,PCDH11X,KCNMB4,ADGRA3,PRUNE2,GPR12,STON1,STMN2,GRIA1,GRIK1,ADAMTS8,GRM8,WIF1,MAEL,RASSF8,TOX2,C1orf94,HNF4G,HNRNPK,NEGR1,AGFG1,C5orf24,NKD1,DOCK7,PLD5,LIX1,ZNF678,ZNF385B,KCNA2,KCNA6,KCNJ3,PAXBP1,NCOA7,MARK1,LRP1B,MEIS2,KITLG,COL28A1,N6AMT1,MTTP,MXI1,MYCN,NCAM2,NEK1,NF1,CNOT4,NOVA1,NUCB2,CHAMP1,OPHN1,PCSK2,PRTG,PDGFRA,CDK14,ABCB1,NALCN,PIK3C2A,FAM218A,ZFYVE21,GPSM2,PURG,MAPKAP1,SCHIP1,NXPH1,SH3KBP1,DRAM2,PPP2R2C,PTPA,KANSL1,RANBP3L,PRKCB,PKN2,PROX1,GDPD1,RELN,WBP1L,SYTL2,SIDT1,QRICH1,WDR25,CNTLN,PTCH1,PTPRG,PTPRZ1,PEX2,PEX5,PPP2R3C,RAB5B,TMEM255A,FAM66C,SH3TC2,RAP1GDS1,KHDRBS2,SLC6A15,ERI2,GTDC1,RFX4,UBR7,RGS4,RGS7,RPRD1A,GSTCD,NEK11,ATP8B4,RPS6KA2,LGR4,PTGR2,SATB1,CSRNP3,SCP2,FNIP1,ELMOD1,KIF21A,CPEB3,AMBRA1,FBXO11,ST3GAL3,SEC31A,NUBPL,ZNF365,PREX2,RUFY2,SLC6A1,SLC8A1,CCDC88A,SLC15A2,SLCO1A2,TET1,CABCOCO1,TMCC1,UNC80,USP33,DOP1A,SON,SOX2,BDP1,DOK5,SPP1,KIF1B,ATP10B,COLGALT2,THSD1,NKAIN2,LRRC4,CEP68,KLHL7,FGD4,PLCB1,SYPL1,KAZN,TBCEL,TMEM136,TBX15,ZFP90,WASHC4,RALYL,SLC19A3,NSD1,ZFPM2,SLC44A1,TK2,TPM1,ZMYND8,KCNE5,PLEKHH2,VLDLR,ETNPPL,XRCC4,PCDH20,ZIC2,GPR158-AS1,UPF3A,DHX33,PRTFDC1,STMN4,PRDM10,SCG2,KCNAB1,FIP1L1,TMEM163,FAM47E,SLC17A6,FZD3,UBE3B,PAK5,SMIM8,ACTR3B,RSPRY1,NETO1,RNF146,SOCS4,SLC4A10" MicroRNA hsa-miR-1826:mirSVR_highEffct hsa-miR-1826:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.74E-123 3.23E-119 5.78E-122 5.33E-121 303 1214 "ADARB2,CCDC85A,GALNT13,CDC7,PTCHD1,NLGN4X,MTUS1,AGT,HACE1,OSBPL6,LRRC7,ARHGAP20,CARNS1,PCDH10,OGT,DPP10,ANK3,ANXA7,DDO,CACHD1,TNRC6C,API5,PPFIA3,APP,ARNTL,CDK13,ZBTB10,NUMB,TMEM108,BARD1,CDK5R1,ARHGEF7,OSGIN2,CACNB2,PTBP2,CH25H,PRC1,LDB2,CCNH,AIFM1,LRBA,CDC27,CDC42,LRRFIP1,CHM,CASC2,PPT2,CLTC,TJP2,C4orf33,QKI,CNN3,AKAP7,COL4A5,SLC25A27,TOGARAM2,MYRIP,FAM171B,CREM,RBM39,SIPA1L1,NCAN,FAM169A,UBXN2A,ST18,RUBCN,USP6NL,EDRF1,DOCK4,GAPVD1,DCAF8,ZFYVE16,KCTD8,TMEM170A,DAPK1,SCRN1,ZNF804A,C8orf34,ZEB2,HP1BP3,MAGI2,DDX46,SV2B,WDR20,DLX1,DMTF1,DPP6,DNM1L,ANKRD46,HIPK3,CNNM1,SEMA3D,TMTC1,YAF2,FAM13A,PHF20L1,ELN,CALCRL,DCTN4,EPB41L2,LRRC17,RASGRP2,RABEPK,EPS8,FABP7,TAOK3,DLC1,FER,FGF13,SLC37A3,NELFCD,COQ5,NBEA,SPECC1,DACH2,BRSK1,PHYHIPL,MEGF11,MEGF10,GABRA3,GAP43,MTHFD2,GART,WASF3,DNER,DCLK2,NUDT21,PCLO,GRIA1,GRIA2,FAM19A2,BVES,NCKAP1L,MIER3,NEGR1,SMAP1,SOWAHA,RBPJ,DOCK7,LRRCC1,IL12A,ZNF678,INPP5B,TUBB2B,METTL21A,KCNC2,KCND2,KCNJ10,KCNMA1,KIT,LIG4,PAXBP1,SYTL4,MARK1,MATN3,MEIS1,MEST,MITF,ERICH3,COL28A1,MRPL42,MSR1,CTNNA3,MTTP,MYO9A,NCAM2,NEK1,NF1,CNOT4,NOVA1,DNHD1,SLC11A2,SMIM11A,NUCB2,TBC1D25,GPR88,PRTG,PDE4D,PDGFRA,PDYN,FAM218A,RETREG1,GPSM2,NLE1,ST8SIA5,MTRF1L,MAPKAP1,SPATA6,RETREG2,EPB41L4B,SH3KBP1,PRKAB2,PRKACB,PRKCB,EPDR1,MAPK9,GDPD1,TMEM260,PTPN13,OCIAD1,SH3TC2,REV3L,RFX4,SLC25A36,NUDT11,ZFHX4,TMLHE,PNMA8A,ROBO1,RPE,SPIN3,ATP8B4,RTN1,SALL1,SCN2A,SCN3A,SCN4B,SUPT20H,SH3BGR,CPEB3,DOCK10,SHC4,CHD9,ST3GAL3,NUBPL,SLC6A1,RAB3GAP1,SPHKAP,SORCS3,SMARCE1,RCOR3,UNC80,DOP1A,SON,MYT1L,KIF1B,CDK19,NPAS3,SPART,CLASP2,STAU1,SEPT8,CEP68,TTBK2,GANAB,NSFL1C,KLHL7,PLCB1,TMEM150C,CAMTA1,AGTPBP1,SATB2,ZEB1,TRIM2,SYNE1,AKNA,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,SIK3,SPX,AP4E1,ZMAT3,NACC2,R3HDM1,NPL,RUNDC3B,CA14,AMOT,SLAIN1,PITPNB,BCL2L13,TBC1D15,SLC13A3,ZIC3,ZNF28,TRIM9,LYPD6,FSTL5,ZSCAN26,ANKS1B,ZNF225,CSDE1,LMAN2L,CIAPIN1,NAV2,SLC17A7,SNX27,FAM47E,MPPE1,EPM2A,SMIM8,FBXO36,ADAMTSL3,JMJD1C,RNF170,SSPN,SLC4A10" MicroRNA hsa-miR-361-5p:mirSVR_highEffct hsa-miR-361-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.12E-123 3.44E-119 6.15E-122 5.66E-121 313 1295 "RALGAPA1,CLK4,NBAT1,TKTL1,NDRG2,ADD3,SORCS1,ERMN,ADORA1,BEND6,MTUS1,HACE1,FAM135A,DPP10,PHF12,PKP4,BCAS1,TNRC6C,ARNTL,ZBTB10,DPY19L3,DCAF5,ZNF599,BMP7,ARHGEF7,OSGIN2,CA8,CACNB2,CAMK2D,RUNX1T1,CBLN1,KRIT1,SLC16A4,CDH2,MAGI1,SRSF11,B4GALT6,CNOT8,NDST3,RAB28,QKI,MAP4K4,AKAP7,ARMC8,AKAP6,LETMD1,AKAP5,SLC4A7,ZNF521,ZFP28,CLOCK,AKAP12,NCOR1,CS,SNCAIP,RGS6,LRRC3B,ATRNL1,CST3,ERC2,UBXN2A,PHF14,CTNND1,CTNND2,CYBB,HDAC9,DGKB,DCC,PITPNC1,ZNF804A,C8orf34,ZEB2,MYEF2,MAGI2,DDX46,ALKBH8,NTM,AK5,G3BP2,MTX3,GRIN3A,DMD,PDCD6IP,E2F6,EBF1,EDIL3,EDNRA,ANKRD46,SYT15,OPTN,FAM13A,MBNL2,KMT5B,ABI2,C8orf37,CALCRL,RCAN2,EPHA5,GPHN,STX2,DENND4A,RTN3,RRAGB,ADGRV1,ABCA8,TAOK3,CEP78,GORAB,FER,FGF1,RGPD5,FOXM1,ANKFY1,SLC37A3,SMC2,STAMBP,ATP2C1,DACH2,MSANTD4,GALC,GATM,SULT1C4,GLRB,GPR75,GLS,PCDH11X,ZNF638,FERMT2,GOLGB1,GPM6A,PCLO,GRIA4,BTN2A1,AP4S1,RABL2A,GUCY1B1,NXPH2,HSP90AA1,HTR2A,FAM95B1,RBPJ,USP54,LIX1,ITGAV,KCNA2,KCNC2,KCNJ3,KCNJ16,KIF5A,KLRC2,HECTD2,GPR155,MAP2,MBNL1,MDM4,MEST,KCTD6,AFDN,MRPL42,RSPO2,MXI1,MYO9A,PABPC1L2A,NDP,SFR1,NF1,ZNF713,TREM2,CNTN3,PCDH9,PCMT1,PDE3A,PDE4B,PDPK1,GPR85,SERPINE2,PIK3R1,GPSM2,FAM216A,PLP1,PCDH18,ANKRD16,PMP2,POLR2F,MINDY2,PPM1B,CRLS1,PPP3CB,KANSL1,PRKACB,PKIA,PRKCB,MAPK8,MAPK9,GRAMD1C,RELN,VPS13C,WBP1L,LRRC49,SYTL2,PIGG,CNTLN,STK32A,ZSCAN32,PEX5,TTC13,PPP2R3C,CEP97,RAP1GDS1,OXR1,ZYG11B,REV3L,ERI2,RFX3,UBR7,SEC61A2,SUGCT,CARF,ROBO2,ROM1,RORB,ELP2,ATP8B4,TCP11L1,LGR4,PTGR2,TRAPPC13,ATXN7,LINC00461,ELMOD1,ASRGL1,SCAF8,SGK1,NTNG1,CHD9,SEC31A,SLC1A3,SLC8A1,RAB3GAP1,CCDC88A,NAPB,TET1,ANKRD36,CMTR2,MYO16,UNC80,SON,PDZD2,MYT1L,FNBP1,ATP10B,ZC4H2,STAU1,RGL1,DIP2A,ADHFE1,KLHL7,RHBDL3,VPS13A,COBL,ANKRD28,DMXL2,ZFP90,ZEB1,RPGRIP1L,PCDHGB7,WDR7,SYNE1,PCDHB9,PCDHB6,PCDHB4,FRYL,AHCYL2,TEX15,PMS2CL,ZFPM2,CRB1,TIAM1,ERCC6L2,CSMD1,RBFOX2,NPL,RGMB,DCBLD1,UGT8,MTCH1,WNT7A,XRCC4,ZNF24,MICU3,FMN2,MKRN3,TCEAL7,ZBTB38,EML6,PLPPR5,SLC30A4,PRDM2,TMEM178A,HPS4,PCDH15,CAB39L,PLSCR4,PARP11,EPM2A,HRASLS,FAM13C,FZD3,FBXO36,ACTR3B,JMJD1C,DPF3,GAN" MicroRNA hsa-miR-106b-5p:TargetScan hsa-miR-106b-5p TargetScan 6.58E-123 3.70E-119 6.58E-122 6.06E-121 271 969 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-17-5p:TargetScan hsa-miR-17-5p TargetScan 6.58E-123 3.70E-119 6.58E-122 6.06E-121 271 969 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-106a-5p:TargetScan hsa-miR-106a-5p TargetScan 6.58E-123 3.70E-119 6.58E-122 6.06E-121 271 969 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,MARCH4,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-519d-3p:TargetScan hsa-miR-519d-3p TargetScan 1.15E-122 6.46E-119 1.15E-121 1.06E-120 271 971 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,OPCML,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-26b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-122 6.67E-119 1.18E-121 1.09E-120 379 1874 "SDE2,ABCF1,ACADM,KDM5D,KLRC4,NLGN4X,MTA3,ZNF608,AGT,NME5,KIAA1324,C1QTNF1,SRPX,FAM135A,EP400,MAP4K3,APBB2,DGKZ,CDC14B,MADD,ARRB1,RGS20,MARCH3,ATP1A1,CCDC181,ATP1A3,ATP2A2,ATP2B1,MPDZ,BCHE,BID,CDK5R1,NAE1,CACNB2,CACNB4,CH25H,BRSK2,LDB2,USP6,SLC16A4,AIFM1,DGKI,SEPT7,CDC25B,ZBED1,CRLF1,RCBTB2,SOCS6,CHM,JAM2,KMT2C,CLTA,FADS2,ABCG2,FHL5,CNTFR,ARMC8,COL4A5,AKAP5,GAL3ST1,ACBD5,NSL1,CLOCK,SUSD5,PLCH2,PDE4DIP,CST3,PLXNA4,SDC3,CTH,GREB1,ST18,CCDC144A,KIAA0408,DCAF8,TOX,MATR3,PITPNC1,ARMCX2,DNAJC6,ZBTB24,MYEF2,GSDME,SNAP91,SACS,SV2B,G3BP2,RABGAP1L,TMCC2,FAM107B,ARNT2,USP3,DTNB,DYRK1A,ANKRD46,EFNA2,EGR3,PLXNC1,EIF4G2,EIF5,ELAVL2,PLEKHA1,ELAVL3,RGS17,PCOLCE2,DCTN4,HSD17B14,TUBD1,LRRC17,IGSF6,ZNF549,CEND1,NRN1,F3,FAM198B,RPS6KC1,CACNG3,FCGR1B,CHST15,FKTN,FDFT1,GTF2IRD2,FGFR3,SUCO,SCARA3,FOXG1,FOXF2,PCYOX1,SYNCRIP,FOXM1,NELFCD,FOLH1,FOLR2,FAM49B,NPTN,CSPG5,GABBR1,GABRA3,GABRB3,ERAP1,INPP5K,FAXC,GCNT2,TUBGCP4,SESN1,BRD8,GLI2,RAB30,TNRC6A,RAB40B,GP1BB,GPR17,GPR22,CNTRL,RAPGEF4,TPPP,GRIK2,ANKRD36BP1,GRM8,KIF3A,GSTT2,ZBTB45,FICD,SLC2A6,HAS2,ATXN2L,HMGB1,TLX1,DHX35,HSF2,HSPA1L,EID2B,IFI16,SHISAL1,IGF1,IL12A,INPP5B,KCND1,KCNF1,KCNN2,KCNQ2,KHK,KIFC3,KLRC2,RAMP2-AS1,L1CAM,LIG4,LSAMP,PACRG,SMAD1,MAT2A,MATN3,LRP1B,MEF2C,ZNF680,DBNL,BLOC1S2,MT1M,N6AMT1,TAGLN3,DDX25,SAMD14,MXI1,MYBPC1,ZNF862,HNRNPM,NAP1L1,NCAM2,NDUFA5,NFE2L2,NKX2-2,CNOT4,PCBP3,NRDC,NUCB2,ODF2,PCSK1,CDK18,PDE4A,PDE4B,PDGFRA,PFKFB3,PFKP,CDK14,SSH1,CCSER2,PLCB2,SLC25A23,ZNF426,PMP22,MAPKAP1,PSAT1,SPATA6,POLG,POLR2F,PKIA,DCHS2,CNNM2,NDUFS7,VPS13C,SIDT1,WDR25,CNTLN,ELOVL2,PTPRO,QDPR,MARCH1,RAB3A,RAD51D,NWD1,ROGDI,ENOX1,RASGRF1,ZMAT4,TRIM68,ERI2,MORC4,RGS3,SEC61A2,SLC25A36,RNASE1,SUGCT,DCUN1D2,SETD5,ALG9,CCDC25,ROM1,RORB,TMEM206,ARMH4,MCMBP,PRR5L,PAQR6,ATAT1,WLS,RYR3,TRAPPC13,TMEM156,RMI1,SAFB,SALL1,SCN2A,LRRTM4,SCP2,SMPD3,SLC30A10,IL17RB,SFPQ,SH3GL2,DOCK10,NTNG1,CHD9,FBXO11,CLSTN1,SLC1A6,PPP4R3A,DHX30,KANSL3,SLC6A9,RAB3GAP1,ZKSCAN3,SORCS3,SMARCE1,SNRPN,TMCC1,FAM126B,MYT1L,SOX3,SOX5,KIF21B,SP4,TEX2,ERC1,ZNF423,KIF1B,CDK19,PBLD,CLSTN2,EPB41L3,ERBIN,INKA2,DIP2A,STX1A,ZC3H4,SUPT5H,SYNE2,ASTN2,TAC3,TAF9,DNMBP,ALG1,KIAA1107,AGTPBP1,SMG6,DMXL2,TCF12,WASHC4,SYNE1,PHF24,USP32P1,TNS2,PCDHA6,KHDC1,ZFPM2,NACC2,ICAM5,ASXL3,TLR4,NR2E1,LILRA4,TPD52L2,TPM3,NR2C2,TRPS1,SSBP2,TUB,CADM1,UBE2H,DNAJC12,VAV1,TOM1L2,MEAF6,ZNF23,ZBTB38,ZNF195,WNK1,MAP3K12,EMSY,PARP6,LMAN2L,HPS4,CAB39L,SLC17A6,NELFE,PARP11,PDSS2,VANGL2,DPF3,ST8SIA2" MicroRNA hsa-miR-200b:PITA hsa-miR-200b:PITA_TOP PITA 1.48E-122 8.32E-119 1.47E-121 1.35E-120 249 815 "ABAT,SYS1,XKR4,CSMD3,ADCY2,SLITRK1,ADD3,SLC12A5,USP31,PTCHD1,NLGN4X,SLC24A4,GPR158,GPRASP2,ANK3,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,DDX3Y,SLC4A4,ATP2B1,SYNJ1,FUBP1,JAZF1,SGCE,FOXK1,CACNB2,CACNB4,THSD7A,CDC42,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,KMT2C,FAM19A5,DNAJB5,MAP4K4,CNN3,CNTFR,SLC25A27,BTF3L4,COL9A2,SLC4A7,CRHBP,CREB5,NCOR2,FEZ2,CSNK1G3,PHACTR3,PLCXD3,CTNND2,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,RIMS3,KCTD8,IP6K1,GIT2,ZEB2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,ELAVL2,PAN3,EPS8,ERBB4,TAOK3,DLC1,TESK2,AMOTL2,PRKAG2,MEX3B,FOXG1,FOXF2,SGIP1,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,CAB39,WASF3,SESN1,PPARGC1A,COPS8,FERMT2,GPM6A,CECR2,CIT,PSIP1,MAP4K5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HMGB1,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,NCOA7,MAP2,LRP1B,ERICH3,MYCN,MYT1,NAP1L2,NCAM1,ZC3H12B,NFIA,OTOGL,NFYA,CNOT4,NOVA1,NPTX1,HCN1,GPR137C,PCDH8,PCSK2,PDPK1,ANLN,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,FAT3,NXPH1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,UHRF1BP1,PTPN13,FAM120C,PTPRZ1,OXR1,ARID4A,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,LRRTM4,SUPT20H,ITSN1,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,SLC1A2,RUFY2,SLC6A1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,SOX1,SOX2,ZCCHC24,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,GSE1,SYT1,ANKRD28,CAMSAP2,WWC1,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,RALYL,PSD3,PUM2,FRYL,ZFPM2,TLL2,ERCC6L2,LRRC8A,RBFOX2,NR2C2,TMEFF2,VLDLR,TBC1D15,WIPF1,NSD2,ZIC3,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,GOPC,PAK5,PHTF2,CERS6,FXR1,GAN,SENP7" MicroRNA hsa-miR-200c:PITA hsa-miR-200c:PITA_TOP PITA 1.48E-122 8.32E-119 1.47E-121 1.35E-120 249 815 "ABAT,SYS1,XKR4,CSMD3,ADCY2,SLITRK1,ADD3,SLC12A5,USP31,PTCHD1,NLGN4X,SLC24A4,GPR158,GPRASP2,ANK3,MAP4K3,APAF1,SHROOM2,CDC14B,ARHGDIA,NUMB,DDX3Y,SLC4A4,ATP2B1,SYNJ1,FUBP1,JAZF1,SGCE,FOXK1,CACNB2,CACNB4,THSD7A,CDC42,ZMYM4,DLGAP2,NOG,CFL2,SOCS6,CHN2,KMT2C,FAM19A5,DNAJB5,MAP4K4,CNN3,CNTFR,SLC25A27,BTF3L4,COL9A2,SLC4A7,CRHBP,CREB5,NCOR2,FEZ2,CSNK1G3,PHACTR3,PLCXD3,CTNND2,USP6NL,DOCK4,DCAF8,HDAC4,MATR3,RIMS3,KCTD8,IP6K1,GIT2,ZEB2,RUSC2,KLHL3,ZC3H11A,DNAJB6,EGR3,GOLGA7,TENM1,ELAVL2,PAN3,EPS8,ERBB4,TAOK3,DLC1,TESK2,AMOTL2,PRKAG2,MEX3B,FOXG1,FOXF2,SGIP1,JKAMP,FAM49B,ATP2C1,MEGF11,MEGF10,GABRB3,CAB39,WASF3,SESN1,PPARGC1A,COPS8,FERMT2,GPM6A,CECR2,CIT,PSIP1,MAP4K5,ARHGAP19,KLF12,BACH2,MIER3,HLF,HMGB1,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,NCOA7,MAP2,LRP1B,ERICH3,MYCN,MYT1,NAP1L2,NCAM1,ZC3H12B,NFIA,OTOGL,NFYA,CNOT4,NOVA1,NPTX1,HCN1,GPR137C,PCDH8,PCSK2,PDPK1,ANLN,CCSER2,KCTD15,PLCL1,PMP22,TRHDE,STRN3,SCHIP1,EPB41L4B,FAT3,NXPH1,MED1,PPP2R2C,PPP2R5C,PPP2R5E,CEP41,PKIA,MAPK9,RELN,WBP1L,PTCH1,UHRF1BP1,PTPN13,FAM120C,PTPRZ1,OXR1,ARID4A,MSANTD2,RDX,FIGN,ZNF532,CARF,FBXW7,CLIP1,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,LRRTM4,SUPT20H,ITSN1,PPM1E,AMBRA1,CHD9,R3HDM2,DZIP1,SLC1A2,RUFY2,SLC6A1,NAPB,SNAP25,MBD5,TMCC1,FAM219A,SOX1,SOX2,ZCCHC24,ZNF423,ARHGAP26,NFASC,CLASP2,ITPRID2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,GSE1,SYT1,ANKRD28,CAMSAP2,WWC1,FBXW11,TCF4,SATB2,ZEB1,TRIM2,CLASP1,RALYL,PSD3,PUM2,FRYL,ZFPM2,TLL2,ERCC6L2,LRRC8A,RBFOX2,NR2C2,TMEFF2,VLDLR,TBC1D15,WIPF1,NSD2,ZIC3,ZNF711,TRIM9,LYPD6,ZBTB38,REEP1,ZFAND5,SMARCAD1,EVI5,ADAMTS9,TMEM178A,NAV3,GOPC,PAK5,PHTF2,CERS6,FXR1,GAN,SENP7" MicroRNA hsa-miR-302b:mirSVR_highEffct hsa-miR-302b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.53E-122 8.56E-119 1.51E-121 1.39E-120 338 1509 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,GPR158,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,ASPH,STX16,B3GALT2,DPY19L3,ATP6V1G2,BACH1,MPDZ,DCAF5,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,ZNF501,AIFM1,SEPT7,LRRFIP1,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,IGFBP7-AS1,ABCG2,C4orf33,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,ANKRD44,SNCAIP,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,HDAC9,TOX,KIAA0586,DGKG,DCC,YTHDC1,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,RABGAP1L,GRIN3A,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,GOLT1B,E2F5,E2F6,WDPCP,EDNRB,ANKRD46,HIPK3,SEMA3D,EGFR,KMT5B,GOLGA7,IRAK4,TENM1,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,VPS26C,DNAJC27,WAC,CORO2B,MED12L,POLK,SUCO,SGIP1,NELFCD,USP16,MSANTD4,ZNF512,MEGF11,CAB39,ZMYND11,ARPP21,IGSF5,TUBGCP4,MSTN,ADAM28,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,UBE2QL1,HPS5,C1orf94,HMGB1,ZDHHC15,HSP90AA1,SMAP1,MSL1,IDH3B,JAK1,OLFM3,KCNMA1,KCNN2,CYP27C1,LAMP2,LIG4,SYTL4,HECTD2,NCOA7,LSS,ZNF667-AS1,MARK1,MDM4,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPA1,OPHN1,GPR137C,PCDH9,PCSK2,PDCD2,PFKP,ZDHHC8,ZNF655,ST8SIA5,PLCL1,JAKMIP1,HMGCLL1,PRIMPOL,TRHDE,PRRX1,SPATA6,EPB41L4B,DRAM2,PPP3CB,RASGEF1B,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,CNTLN,PTHLH,PXK,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,RET,GTDC1,FIGN,RFX3,RIC8B,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,TMEM100,MCMBP,LGR4,RPS20,RTN1,AMER2,SCN2A,SCN3A,IL17RB,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,YPEL4,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,SOX2,TNIK,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,UNC5D,ADGRL3,TBCEL,TCEA1,CUX2,ZEB1,SZT2,PCDHB3,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,NACC2,NR2E1,TNS1,TPD52L2,RGMB,PRMT8,TRPC1,PPIL6,FAM181B,ZNF709,VLDLR,PCDH20,TRIM9,FMN2,LYPD6,LAMP5,SYNC,WNK1,CADM2,PRDM2,PRTFDC1,RGMA,PRDM8,PRDM10,PCDH15,SLC17A6,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-649:mirSVR_lowEffct hsa-miR-649:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-122 9.15E-119 1.61E-121 1.48E-120 334 1475 "TTYH1,GPRIN1,CSMD3,ADCY8,ADD2,ERMN,PLEKHH1,CC2D2A,HFM1,SEMA6A,ARHGAP20,MRTFA,ZFAT,LCORL,MAP4K3,APAF1,BCAS1,LGR5,CDC14B,PPP4R4,TMEM263,ASGR1,NUMB,RASL11B,ATP2B2,SLC2A11,MTMR9,N4BP2L1,RIPK1,TTLL9,BACH1,SNAI3-AS1,DCAF5,BID,CFLAR,ARHGEF7,MMD2,PTBP2,CAMK2G,TRIM41,VSTM2A,MAP7,PRC1,AIFM1,NEURL1,CDH2,SOCS6,CHM,CHN2,CASC2,NDST3,KMT2C,NRXN3,IGFBP7-AS1,ZFYVE9,KIAA1549L,FBXO7,DNAJB5,QKI,ARHGEF6,ARMC8,AKAP5,SLC4A7,ABI3BP,AHCTF1,ACBD5,CHD1L,CLOCK,C2CD2,CRMP1,ANKRD44,CS,CHD5,VCAN,NCAN,PDE4DIP,CTH,ST18,DOCK4,RIPOR2,SNPH,ARHGAP24,KIAA0586,DGKB,DGKG,AIF1L,ARMCX4,C8orf34,MFAP3L,KIAA0319,DDX46,GRIN3A,DPYSL2,GNE,DNAJB6,FAM135B,EDNRA,SGK2,HIPK3,CNNM1,RASGRP1,SEMA3D,SIDT2,MRO,EIF5,IRAK4,TENM1,PLEKHA1,EML1,EN2,EPB41L2,ETV1,ADGRV1,TAOK3,ATP8A1,TOMM40L,FKTN,FER,POLK,FOXG1,IQCG,ZMYND15,TACC2,SMC2,UFM1,TPK1,KHDRBS3,DACH2,STAU2,PNMA2,ADGRA1,OGA,SDCBP2,CHL1,GABRB1,GABRB3,BRPF3,FAM120B,ZMYND11,RAPGEF6,DISC1,WASHC2A,AHDC1,PCDH17,PPARGC1A,MALT1,ZNF276,RND1,TCERG1,HPGDS,MSL3,LUZP2,GOLGB1,PRUNE2,STON1,NUDT21,RAPGEF4,GRIA1,GRIA2,SPACA9,ADAMTS13,GRM1,PRDM5,ZBTB49,RABL2A,FAM222A,WIF1,RASSF8,HMGCL,TLX1,ZDHHC15,NEGR1,IDH3B,RBPJ,SCIN,LRRTM3,JAK2,KIF5C,MAN2A2,MAP2,MATN2,SYT9,LRP1B,MEIS1,MEIS2,KCTD6,PPM1L,MOBP,MSI1,RSPO2,MXI1,NEK1,NEUROD1,ALDH1L2,CNOT4,OPCML,OPHN1,PCSK1,PDGFRA,GPR85,BEST3,NALCN,A2ML1,SNX10,CDIP1,ING3,RETREG2,SEPT4,TNPO2,POU3F2,PPARA,MED1,MINDY2,PPM1B,MAPK7,LRRC49,MDGA2,ELOVL2,ZSCAN32,ACSM5,NKAIN1,TMEM231,ZNF793,RAP1GDS1,DBX2,ZDHHC14,TRIM68,RET,REV3L,RNF220,NUDT11,RPRD1A,ZNF532,ALG9,ROBO2,TMEM206,ELP2,TMEM100,SPIN3,LGR4,MEG3,SGK1,ZFP30,ITSN1,PPM1E,FERMT1,FNDC3A,SEC31A,DZIP1,ZNF365,SLC2A5,LRRC55,SLC8A2,RAB3GAP1,SLC12A2,SLCO1A2,SPHKAP,SLC22A4,NAXD,ZFP1,SMARCE1,ANKRD36,UNC80,USP33,SCN3B,DOP1A,SON,ZSWIM8,NMNAT2,CAND2,ZC3H13,IQSEC2,NFASC,C11orf87,SRPK2,TAB2,COLGALT2,ITPRID2,LARP4,SEPT3,FGD4,PLCB1,ATP11A,MTCL1,SEMA4A,DNMBP,KLHL4,TBX15,TCF4,DMXL2,SATB2,TCF7,TPCN2,SYNE1,DOCK9,PHF24,RALYL,NSD1,AHCYL2,HIF3A,DICER1,DICER1-AS1,C18orf54,ZNF106,SLC44A1,TIAM1,HEY1,ASXL3,HEY2,TP53BP1,TPD52,TPM3,SYNPO2,ELP5,TSC1,TTTY15,TTC3,CLHC1,AMOT,PITPNB,CLIP2,GUSBP1,ZNF24,TRIM9,LYPD6,PMEPA1,EMSY,RGMA,PCDH15,NAV3,NAV2,KAT6A,FAM219B,IFT88" MicroRNA hsa-miR-488*:mirSVR_lowEffct hsa-miR-488*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.16E-122 1.22E-118 2.14E-121 1.97E-120 343 1554 "ADD3,SLC24A4,AP2A2,ZNF608,PCDH19,SYT13,AMPD2,AMPD3,LRFN1,LRCH2,ANK3,CNIH2,APC,GPAM,PRX,IGDCC4,CADPS,ASPH,ATM,SLC2A11,B3GALT2,TTLL9,RGS9,ARHGEF7,GPC2,KALRN,TRIM41,RUNX1T1,CBLN1,CLDN10,REPS2,CDH2,LRRFIP1,LGI1,CCPG1,SRSF11,CHN1,CASC2,RAB3C,JAM2,TAOK2,LSMEM2,NRXN3,PPT2,CLCN4,COG1,CNR1,CNTN1,IQCK,AKAP6,COL9A1,HS3ST5,RBM39,AKAP12,RNF14,SNCAIP,LRRC3B,ATRNL1,VCAN,SOCS5,PDE4DIP,CNTNAP2,UBXN2A,GREB1,USP6NL,CX3CR1,BOC,RIPOR2,DCAF8,FRMPD4,LONRF1,MATR3,KIAA0586,MAML1,DGKB,SPOCK2,IP6K1,DBI,YTHDC1,C8orf34,CNIH3,MFAP3L,TMEM130,LYPD1,RHOBTB1,SNAP91,WDR20,EXOG,CASP8AP2,FAM78B,E2F6,AASDH,EDNRA,SYT15,KLHL5,RBM12,EFNB3,FAM13A,PLXNC1,ELAVL2,RGS17,CALCRL,PAN3,EN2,OLIG2,SEZ6,EPHB1,RABEPK,EPS8,DENND4A,F5,FAM198B,ZNF461,TUBB4A,FCGR1A,FKTN,ZNF589,FGF13,SUCO,SYNCRIP,EVL,ANKFY1,NBEA,TPK1,ATP6V1H,ZNF605,MSANTD4,STAG2,MEGF11,TRAF3IP2,GAD2,B4GALNT1,RAPGEF6,ZNF274,NEK6,IP6K3,IQGAP2,C15orf41,ATP8A2,IGSF5,MSTN,NFU1,ADAM28,GGTA1P,GGT7,GHR,LYVE1,GK,TOX3,TNRC6A,PCDH11X,LUZP2,DCLK2,GPD2,GPM6B,LILRA1,DIDO1,GRIA4,NR3C1,GRM5,FAM19A2,RNF165,BVES,SOX21,ATG4C,HAS2,NXPH2,MAN1B1,HNRNPK,ZDHHC15,HSP90AA1,MSL1,IDH3A,C5orf24,LIX1,IBA57,BRINP3,INPP5B,ZNF385B,SLC35G1,KCNH1,KCNJ3,KCNMA1,KIF2A,KIF5C,KIT,LAMP2,NAT8L,MAP4,MATN3,CHIC1,KCTD6,PPM1L,MOBP,ZNF680,BLOC1S2,BCO1,N6AMT1,MYBPC1,MYH3,LAYN,MYO9A,ZNF862,PABPC1L2A,HNRNPM,NF1,NOVA2,NPR2,OMG,OPHN1,CLDN11,TREM2,CNTN3,PDE4D,SLC10A4,A2ML1,CCSER2,KCTD15,PDZRN4,LRP12,SPATA6,FAT3,POU3F2,PPM1B,PTPA,PPP2R5C,PRKCB,NDUFS7,MDGA2,PTHLH,PXK,PTPN13,PTPRB,PTPRE,TTC13,MARCH1,RALGDS,NWD1,KHDRBS2,ZYG11B,RFX4,ARHGEF10L,RPRD1A,CCDC82,ALG9,RAVER2,CARF,NEK11,SPIN3,GLDN,RTKN,AP1AR,SALL1,CSRNP3,SCN2A,SCP2,SEC14L1,KIF21A,FBXO11,FNDC3A,NLGN1,ZNF365,PPP4R3A,SLC6A1,PKNOX2,SLC6A11,RAB3GAP1,CCDC88A,SLC9A5,ATF7IP,CPEB4,NAXD,SMARCE1,MBD5,LMBRD1,PDZD2,ENKUR,MCF2L2,NFASC,COLGALT2,STOX1,EPB41L3,ZC4H2,LRRC4,SEPT8,DIP2A,STX1A,GSE1,KLHL7,VPS13A,PLCB1,SYT4,TACC1,KAZN,PJA1,TBCEL,FBXW11,TBX15,TCF4,DMXL2,SATB2,TCF7L2,CLASP1,DOCK9,FAM189A1,PCDHB4,PCDHA5,FRYL,AHCYL2,TEX15,PMS2CL,DICER1,AP4E1,TGFBR3,HHIP,SLC44A1,FBXL16,DDHD1,TRPC1,RUSC1,CA14,ANO5,TUB,CADM1,FAM155A,FLRT2,ZNF24,ZNF540,CRB2,REEP1,TMEM237,LAMP5,CSDE1,GAL3ST3,FIP1L1,SLC17A6,RGS7BP,FZD3,PHTF2,CASC15,FAM219B,JMJD1C,CPNE4" MicroRNA hsa-miR-27b*:mirSVR_lowEffct hsa-miR-27b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.78E-122 2.12E-118 3.72E-121 3.43E-120 313 1303 "NDRG3,ADD1,SORCS1,GRAMD1B,PTCHD1,ADRB2,SLC24A4,PCDH19,HACE1,HFM1,PCDH10,FAM135A,LCORL,CNTNAP1,TNRC6C,SHTN1,MARCH3,ASPA,ASPH,RASL11B,SLC4A4,MTMR9,BCL2L2,DCAF5,KSR1,ARHGEF7,MTMR2,C5,BTRC,CACNB2,CACNB4,KALRN,CAMK2D,HIP1R,CBR1,TMEM257,ENTPD6,REPS2,PLEKHB1,CASC2,CNOT8,NDST3,RAB28,ZFYVE9,CLTC,C4orf33,SRP14-AS1,MAP4K4,NIPBL,CNN3,ARHGEF6,ARMC8,COL4A5,AHCTF1,MFSD4A,CREM,CREB5,GDA,TENM4,LRRC3B,MICAL2,DZIP3,SDC3,ERC2,ARHGAP32,HDAC4,EARS2,PABPC5,DNAL1,ARMCX2,DCTN1,C8orf34,MAGI2,GUCD1,POM121,AK5,CCDC3,KIF19,EXOG,GRIN3A,NR1D2,SLC12A6,ATN1,DNAJB6,ABCC5,ABCC9,EBF1,SGK2,HIPK3,SEMA3D,TMTC1,FRY,FAM13A,EGFR,EGR3,COPS4,TENM1,PLEKHA1,PAN3,USPL1,EN2,VPS13B,KCNMB2,GPHN,GMPR2,MRVI1,ARMCX1,FAM198B,DLC1,FKTN,SLC9B2,FER,GTF2IRD2,FGF11,PRKAG2,CAP2,FOXM1,FLT1,NBEA,USP21,NPTN,ZNF605,CELF1,MEGF11,DKK3,GABRA2,DISC1,CPLX2,ARFIP1,MALT1,CRCP,RAB30,GLS,TOX3,MSL3,GNAS,FERMT2,GPM6A,DIPK1C,GPR34,NUDT21,GRIK1,GRM1,GRM7,ZNF496,AP4S1,RNFT2,HPS5,MIER3,HLF,HMGCL,HMGCR,TCEAL6,SHISA6,EID2B,MSL1,ZIC5,RBPJ,KNDC1,PLD5,IL12A,TUBB2B,METTL21A,OLFM3,KCNJ3,KCNK2,CREG2,KIF5C,NCOA7,SMAD9,ZNF667-AS1,MBD1,MBNL1,CHST6,MEIS1,MEIS2,MMP16,MOBP,ZNF680,RSPO2,MXI1,TCEAL5,HNRNPM,P2RY13,ZC3H12B,ALDH1L2,NNAT,CNOT4,NOVA1,SLC11A2,NUCB2,LOC100128398,PDE3B,PDGFRA,SERPINI1,TMIE,XRN1,FAM216A,PRIMPOL,STRN3,PRRX1,ING3,PPM1B,RANBP3L,PRKAB2,GON4L,MTMR10,PTPN13,PTPRB,OCIAD1,CASTOR1,PTX3,PEX5,CEP97,RALGDS,RBBP6,VEPH1,KHDRBS2,ZDHHC14,BSDC1,RDX,FIGN,RFX4,RIT2,RNF220,PBRM1,RAVER2,CCDC102B,NEK11,ABCA11P,ATAT1,SATB1,ATXN1,SCN7A,FAM19A1,SCN8A,SCP2,KIF27,KIF21A,ITSN1,SH3GL3,FBXO11,FNDC3A,SLITRK3,CNKSR2,DZIP1,ANKRD6,PEX26,KANSL3,LRRC55,SLC8A3,SLC14A1,NAPB,SPHKAP,TET1,DMRTC1,RCOR3,ANKRD36,MBD5,CMTR2,SNRPN,FAM126B,MYO16,UNC80,KDM4B,SCN3B,SOX2,ZSWIM8,NPAS3,ATP10B,STOX1,NSFL1C,NECAB1,FGD4,SYNE2,VPS13A,TACR1,DDHD2,WSCD1,SATB2,RPGRIP1L,SYNE1,RALYL,ARHGEF12,ZFPM2,CRB1,TMEM9,RIMBP2,R3HDM1,TTTY15,TUB,ZKSCAN5,SGK3,DNAJC12,ZNF709,VLDLR,WIPF1,GUSBP1,SLC13A3,XPO1,ZIC1,MICU3,KCNT2,ANKS1B,ZNF213,EMSY,PRTFDC1,PRDM8,URM1,WIPF2,DOCK8,FXR1,SLC4A10" MicroRNA hsa-miR-541*:mirSVR_highEffct hsa-miR-541*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.84E-122 2.16E-118 3.78E-121 3.48E-120 330 1445 "CPNE2,CLK4,NCKAP5,SYS1,ACTN2,KDM5D,GALNT13,ADD1,AXIN2,ERMN,ADORA3,PCDH19,KIAA1324,TXNDC16,AK2,LRRC7,SPOP,ALCAM,ABCD2,ANK2,ANK3,PHF12,API5,ARNTL,ARRB1,CAPRIN2,ASPH,NUMB,DDX3Y,ATM,ATP2B1,ZNF582,N4BP2L1,TTLL9,BCL7A,DCAF5,BMPR1B,JAZF1,PRMT9,IL33,USP6,SLC16A4,LRRFIP1,LGI1,CIART,SRSF11,B4GALT6,JAM2,LSMEM2,IGFBP7-AS1,PLAA,COG1,ARMC8,SLC4A8,RTTN,ACBD5,PNKD,HAPLN1,HINFP,ANKRD44,CS,MROH8,CHD5,VCAN,NCAN,PLXNA4,CTH,CTNND1,HDAC9,FGFR1OP2,TOX,ZFYVE16,LONRF1,TBC1D5,DGKB,ARMCX4,C8orf34,CEP170,FBXO25,AK5,SGSM2,FAM107B,HS3ST4,NR1D2,DPYSL2,DTNA,FAM78B,DNAJB6,DNM1L,E2F6,EDNRB,ANKRD46,FRY,FSD1L,OPTN,KMT5B,ABI2,COPS4,EML1,CALCRL,PAN3,EMX2,VPS13B,F5,CLVS1,ZNF461,SH3YL1,CEP78,FCGR3A,KIAA1109,FGF14,ATP13A4,ANKFY1,SMC2,NPTN,CAMKK2,ATP2C1,DACH2,ST6GALNAC3,NRG3,DKK3,GABRA2,HRASLS5,GABRB1,GABRG2,AHCYL1,DISC1,TUBGCP4,ARFIP1,PCDH17,PPARGC1A,BRD8,GK,GLYR1,GLS,ZNF638,INSM2,GNAL,GNAS,GPM6A,LPAR4,RAPGEF4,GRIA4,GRID1,GRIK4,GRM5,GRM7,ZNF496,KIF3A,MAP4K5,FRMD3,GABARAPL2,SMAP1,HTR2A,DISP2,PLD5,LRRTM3,JAK1,KCNK1,KCNN3,KIF2A,STXBP5,KTN1,SFXN5,VWA5A,HECTD2,MAP4,MATN2,TM6SF1,MDM4,MEIS2,SRSF12,MMP16,MOG,MRPL42,JAKMIP3,MSR1,SCG3,CTNNA3,NAP1L1,NAP1L2,NELL1,DNHD1,SETD4,IGSF11,OPHN1,PAH,CNTN3,PAX6,PCDH9,CDK18,PDE1C,PDGFRA,BEST3,OLA1,GDAP1L1,PIK3C2A,GPSM2,PCDH18,MTRF1L,TRHDE,PSAT1,ING3,SPATA6,EPB41L4B,SLC36A4,DRAM2,PPP2R5E,RANBP3L,MAPK7,VPS13C,MDGA2,CNTLN,PTHLH,PTPRE,TMEM255A,FAM66C,FAT4,DBX2,RFX3,RGS12,KCTD17,RNASEL,CCDC82,CARF,PCMTD2,RPL15,UEVLD,BAALC,ZC3H14,ADAL,ACER3,PTGR2,RTN1,ZNF331,AP1AR,RMI1,ATXN7,SCN7A,FNIP1,SELL,CASC3,NLGN4Y,SGK1,SH3GL2,PPM1E,DOCK10,MAGI3,FNDC3A,ZNF365,PREX2,EPN2,WDR47,RUFY2,SLC6A1,SLC8A1,BTBD7,ATF7IP,SMARCE1,RIMS1,UNC80,SOX2,ZCCHC24,BDP1,ENKUR,ZC4H2,LRRC4,APOM,NECAB1,JMJD6,PRRC2C,VPS13A,DDHD2,CAMSAP2,UNC5D,FBXW11,TBX15,EHBP1,VWC2,SATB2,TCF12,PCDHGB7,WDR7,SYNE1,PCDHB6,PCDHB3,PUM2,RNF175,ITGB3BP,AP4E1,TJP1,HEY2,TMPO,KAT6B,PIK3R5,TPM2,TPM3,AMACR,SSBP2,ZKSCAN5,UBE3A,PITPNB,PLEKHH2,USP1,ZNF781,ZNF708,MICU3,FMN2,GPR158-AS1,ZNF138,FSTL5,ZNF189,ANKS1B,DHX33,EMSY,PRDM2,STMN4,ADAMTS9,PCDH15,FAM47E,WNK3,C12orf4,PDSS2,HNRNPA3,CAMK1G,TIGD6,MSRB3,FRMD6,CBLN2,ST8SIA2" MicroRNA hsa-miR-93-5p:TargetScan hsa-miR-93-5p TargetScan 3.88E-122 2.18E-118 3.80E-121 3.50E-120 270 968 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-20b-5p:TargetScan hsa-miR-20b-5p TargetScan 3.88E-122 2.18E-118 3.80E-121 3.50E-120 270 968 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-20a-5p:TargetScan hsa-miR-20a-5p TargetScan 3.88E-122 2.18E-118 3.80E-121 3.50E-120 270 968 "NCKAP5,ADAR,RNF150,PTCHD1,ADRA1B,APBB2,APP,MARK4,CAPRIN2,RASL11B,ATP1A2,ATP2B2,B3GALT2,NOL4,MPDZ,BCL2L2,BID,ARHGEF7,MTMR3,JAZF1,MAP7,FMNL3,REPS2,DLGAP2,CFL2,GPR37L1,B4GALT6,KMT2C,QKI,PCYT1B,ARMC8,AHCTF1,ACBD5,HS3ST5,CLOCK,C2CD2,ENTPD4,CREB5,CRY2,NCOR1,GDA,CSF1,LRIG1,ARHGEF10,IPCEF1,CHD5,APPL1,PLCXD3,NRSN1,RIMS2,PPP6R2,FAM131B,CCDC144A,DOCK4,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,GIT2,DNAL1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,SACS,DNM2,DPYSL2,DRD1,ABI1,DNAJB6,DYRK1A,E2F5,FEM1B,FSD1L,FAM13A,EGFR,EIF4G2,ELAVL2,CERCAM,RGS17,MTSS1L,EPHA5,ETV1,DNAJC27,KATNAL1,EZH1,F3,ACSL4,SCML2,CORO2B,MED12L,FGF12,FLT1,ANKFY1,NBEA,PDLIM5,FYN,GAB1,GAD2,SALL3,RAB30,GPD2,GPR37,RAPGEF4,RAPGEF1,ATE1,CIT,IL1RAPL1,BVES,FICD,ATOH8,HAS2,HPS5,KLF12,MIER3,HLF,HTR2A,MSL1,IL6ST,SCRT2,ITPKB,JAK1,KCNB1,KCNJ10,KIF5A,KPNA5,CAMK2N2,HECTD2,ARHGAP12,CHIC1,LDLRAD3,LRP1B,SCAMP5,MID1,MKLN1,AFF1,MXI1,MYCN,MYO9A,NBL1,NEUROD2,NHLH1,NKX2-2,OCRL,GPR137C,KCNK10,PAK3,PDE3B,PDE1B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PKD1,PURG,LRP12,PRRX1,FAT3,POU6F1,PPARA,PRKACB,PKIA,PKN2,MAPK4,FITM2,CNNM2,PSD,PTHLH,PXK,PTPRD,MARCH1,RAB5B,CEP97,ATG16L1,FAT4,OXR1,RASGRF2,ARID4A,REV3L,GTDC1,FIGN,RGS4,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,AMER2,SALL1,SATB1,CSRNP3,ATXN1,SCN2A,SCN2B,FAM19A1,GALNT10,FAM102A,CPEB3,NTNG1,CHD9,FNDC3A,RUFY2,LRRC55,BTBD7,MBD5,CMTR2,FAIM2,PALLD,FAM126B,MYT1L,ERC1,ARHGAP26,KIF1B,IQSEC2,NPAS3,LMO3,CAMTA2,RGL1,DIP2A,AJAP1,FAM168A,FGD4,C3orf70,PLCB1,ANKRD28,ATP11A,ANKRD12,MCF2L,FBXW11,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AKTIP,NACC2,ASXL3,DDHD1,DOK6,RGMB,NR2C2,FRRS1L,LYPD6,DPYSL5,LAMP5,MAP3K12,CADM2,LRP8,RGMA,PARP6,PRDM10,NAV2,PLSCR4,FAM13C,FZD3,MARCH8,PHTF2,CERS6,FAM219B,FXR1,FRMD6,NETO2,DPF3,GAN" MicroRNA hsa-miR-135a:mirSVR_highEffct hsa-miR-135a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.26E-122 2.96E-118 5.13E-121 4.73E-120 329 1438 "ABAT,ADAR,ADCY6,GALNT13,PLEKHH1,PTCHD1,KIDINS220,INTS2,MTUS1,LRRC7,ALCAM,LRCH2,ANK3,PHF12,PKP4,ANXA7,CNTNAP1,APC,API5,TMEFF1,ZFYVE28,ARNTL,RGS20,PDE8B,ASPH,NUMB,ATP1A2,ATP2B3,CADM3,N4BP2L1,NOL4,ADAM23,BACH1,DST,ARHGEF7,CA12,CACNA1D,CACNB4,CALM1,KALRN,PTBP2,CAMK2G,CAPN3,RUNX1T1,ZNF501,LDB2,ARHGEF2,KCNAB3,L3MBTL4,LOC730101,UBE2L6,SOCS6,QKI,ARHGEF6,CNTN1,FAM149A,ZFP28,PREPL,ENTPD4,HAPLN1,RGS6,ARHGEF10,MICAL2,CSNK1G3,ATRNL1,VCAN,SLITRK5,APPL1,UBXN2A,CFAP61,NRSN1,BOC,ARHGAP32,FRMPD4,LONRF1,KIAA0586,PITPNC1,JAKMIP2,MYEF2,CEP170,GSDME,DDX46,FAM107B,CHRDL1,EXOG,RAB39B,PDCD6IP,E2F5,EBF1,EDIL3,EDNRA,ANKRD46,SGK2,HIPK3,YAF2,PHF20L1,GOLGA7,PLEKHA1,CERCAM,MRNIP,COQ7,SRRM1,EFS,TMEM74,EYA1,MRVI1,F8,CLVS1,FAM198B,FABP7,ZIC4,SCML2,FDFT1,FGFR1,POLK,HPCAL4,CAP2,SYNCRIP,PSD2,NBEA,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,STAU2,TVP23A,OGA,GABRA2,ERAP1,CPLX2,GCNT2,HEPN1,GHR,PPARGC1A,BRD8,RAB30,GLRB,GNG3,FERMT2,GPM6B,RAPGEF4,GRIA4,NR3C1,PSIP1,HPS5,ELOVL5,AGBL5,ZDHHC15,OPALIN,IRF8,USP54,LIX1,IL6ST,ZNF385B,ITGAV,JAK2,KCND1,KCNMA1,KIF5C,STMN1,MBD1,SYT9,MDM4,MEIS1,MRPL42,ZNF92,MTTP,MYO6,NAP1L2,P2RY13,NEFM,NODAL,NPTX1,HCN1,NTRK2,OXTR,PBX1,PCDH9,PDCD2,PDE3B,GDAP1L1,ANLN,PLP1,PCDH18,PURG,STRN3,SCHIP1,PRRX1,SDK2,DRAM2,MINDY2,PPM1B,CRLS1,PPP2R5C,PKN2,MAPK9,GDPD1,MASP1,RELN,LRRC49,APTX,MDGA2,ELOVL2,PTK2,ZSCAN32,RAP1GDS1,ZCWPW1,ENOX1,VEPH1,RDX,ERI2,RFX5,SLC25A36,PBRM1,ROBO1,CCDC25,RORB,PCMTD2,ATAT1,FAM182A,TMEM156,MIR124-2HG,ATXN7,SCN2A,SCN8A,SELL,PPM1E,ASAP3,NTNG1,ST3GAL3,NUBPL,SLA,ZNF365,SLC6A1,SLC6A9,ZNF430,SLC8A1,RAB3GAP1,CCDC88A,SPHKAP,ZFP1,ZNF667,COA1,SMARCE1,RIMS1,MBD5,SNRPN,DOP1A,PDZD2,ZCCHC24,BDP1,HECW1,ZNF302,LRRC4,NXT2,SEPT8,RGL1,DIP2A,KANK1,ARC,POPDC3,MTCL1,CNTN2,TMEM136,KLHL4,ANO4,ATMIN,SATB2,CUX2,TCF7L2,TCF12,WASHC4,WDR7,SYNE1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,SLC44A1,TMEM9,BHLHB9,ERCC6L2,FAM124A,C5orf64,KAT6B,NPL,SYNPO2,TRPC1,CLHC1,RPL7L1,UGT8,PITPNB,VLDLR,TBC1D15,WIPF1,XRCC4,ZNF708,TRIM9,FMN2,NDRG4,ZNF138,TMEM237,FTSJ1,ZFAND5,INTS3,EMSY,DNALI1,EVI5,STMN4,RNF103,NAV3,TMEM163,CAB39L,MVB12B,PLSCR4,DOCK8,ST7,RTN4,PAK5,CAMK1G,KLHDC1,FRMD6,IFT88,NETO2,SLC4A10,GAN,FAM198A" MicroRNA hsa-miR-770-5p:mirSVR_lowEffct hsa-miR-770-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.26E-122 2.96E-118 5.13E-121 4.73E-120 329 1438 "RALGAPA1,ACADM,CSMD2,KLHL32,PLEKHG5,ADD3,SNX32,OSBPL8,UNC79,FAM135A,BEGAIN,AMPD2,PPFIA1,EPB41L5,APP,IGDCC4,ZFYVE28,ARHGAP5,ARNTL,MARCH3,ZBTB10,NUMB,BACH1,MIR9-3HG,CDK5R1,CACNA1I,OSGIN2,CACNB2,CABP7,PTBP2,CAST,USP6,AIFM1,CD86,SCARB1,TMEM257,CDH2,CDH8,LGI1,CDO1,DIS3L,SRSF11,CHM,CASC2,NDST3,KMT2C,CLCN3,NMT2,CLTC,ABCG2,SULT4A1,WHRN,SUMF2,BTF3L4,SLC4A7,ACBD5,ZNF521,CNRIP1,MFSD4A,HS3ST5,CS,ARHGEF10,MICAL2,ATRNL1,NCAN,SLITRK5,ERC2,PHF14,PNPLA8,CTNND1,CTNND2,USP6NL,ECE2,ARHGAP24,TOX,DAPK1,ELMO1,TIAM2,RUSC2,COPS7A,KIAA0319,ALKBH8,PLPPR4,NTM,AK5,G3BP2,RABGAP1L,RAB39B,DMD,FAM57B,ATN1,ECM2,TOM1,DNAJB6,ABCC5,KRBA2,E2F5,EDNRB,ATL1,ANKRD46,SGK2,FAM13A,PHF20L1,MBNL2,ABI2,GOLGA7,ELAVL2,CALCRL,EIF1,MFSD10,LRRC17,EPHA5,ZNF549,EYA1,TMEM132C,TUBB3,TOMM40L,FER,FGF13,FGF14,FGFR1,BAIAP2,SUCO,IP6K2,FOXM1,FLT1,APOPT1,TPK1,ZNF605,KHDRBS3,OGA,ZMAT1,STAG2,GAB1,GABRA5,GAD2,GALR1,SALL3,ZNF274,C15orf41,KIAA1841,GCNT2,SESN1,ADAM28,MALT1,ZNF638,MAP7D2,PSRC1,GPD2,GPM6B,DIDO1,ADAMTS13,WIF1,HAS2,MAN1B1,SHISA6,SMAP1,ZNF181,GAREM2,RBPJ,ZNF678,LRRTM3,JAK2,SLC35G1,KCNA6,KCNJ11,KCNN2,LAMP2,LMO1,PACRG,MAOB,MATN3,MBD1,MDM4,MEIS1,KCTD6,KITLG,WDR49,MOG,MRPL42,CCDC80,N6AMT1,MX1,MYCN,NACA,FXYD6,RCOR2,NELL2,NEUROD1,NFE2L2,NINJ2,NNAT,NOVA1,NPR2,SMIM11A,NTRK2,NUCB2,ENPP2,CYTL1,SEMA5B,PIK3R1,ZNF655,PCDH18,MTRF1L,PURG,RC3H2,LRP12,EXOSC10,PPARA,PPP3CB,NKAIN4,PRKCZ,SAMD9,PTCH1,UHRF1BP1,PTPRB,PTPRE,PEX2,PYGM,TUG1,CEP97,TMEM255A,RASGRF2,ZYG11B,REV3L,FIGN,RFX4,RFX5,PRIMA1,ZFHX4,ALG9,ROBO2,RORB,RPE,SNX22,ACER3,RYR3,ASIC4,ELMOD1,SEC14L1,RASA3,HSPA4L,SGK1,ITSN1,ASAP3,CPEB3,CHD9,FNDC3A,BCAN,PAAF1,BTBD3,SPHKAP,MYH15,RCOR3,LMBRD1,SNRPN,MYO16,USP33,ZBTB43,RBM26,ZNF621,STOX1,EPB41L3,NKAIN2,ERBIN,MAPK8IP3,STAC2,SULF2,AJAP1,NECAB1,JMJD6,PRRC2C,MTCL1,TAF9,TMEM136,ANO4,VWA3A,ZFP90,TCF7,ZEB1,TRIM2,FRYL,RNF216P1,FAM200B,SIRT1,CRB1,SPX,ZMAT3,TMOD1,FAM124A,RIMBP2,KAT6B,TPM1,TPM3,ELP5,TRPS1,FNDC5,SSBP2,ZKSCAN5,AMOT,GORASP1,PLEKHH2,USP1,BEST1,WIPF1,NSD2,TRIM9,GPR158-AS1,SLC26A10,SPHK2,SPIRE1,ZFAND5,EMSY,SLC38A1,HPS4,PDSS2,GOPC,FAM13C,ST7,RTN4,HNRNPA3,PHTF2,NUP214,ADAMTSL3,TRAM2-AS1,RNF170,KLHDC1,SOCS4,FAM181A" MicroRNA hsa-miR-196a:mirSVR_lowEffct hsa-miR-196a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.52E-122 3.10E-118 5.38E-121 4.95E-120 309 1272 "CLK4,ACTN1,FAM43B,GALNT16,GALNT13,USP31,ADRB2,KIDINS220,BEND6,SLC44A5,HECW2,PCDH19,OSBPL1A,KIAA1324,AK2,ALCAM,ARHGAP20,FAM135A,DOC2A,AMPD2,AMPD3,EP400,LCORL,PPFIA2,LGR5,AQP4,IGDCC4,CASK,CDK13,ASCL1,ZBTB10,CHRD,TMEM108,ATP1B3,ATP2B1,TTLL9,BACH1,CFLAR,KSR1,GYG2,CACNB4,CAST,CLDN10,CCKBR,METTL6,CD86,DGKI,SEPT7,CDH8,ADGRG1,SRSF11,ASIC3,RAB3C,B4GALT6,NDST3,PLAA,COG1,TPP1,ABCG2,C4orf33,SRP14-AS1,AKAP7,LETMD1,SLC4A7,SLC4A8,AHCTF1,SMARCAL1,MFSD4A,CS,RGS6,VAC14-AS1,FAM169A,DZIP3,PPP1R16B,APPL1,UBXN2A,CFAP61,CTNND2,NRSN1,GAPVD1,FRMPD4,ZFYVE16,TOMM20,ELMSAN1,C8orf34,ZBTB24,COPS7A,BLOC1S6,SRGAP3,DLG2,SLC29A4,DOCK2,DMTF1,DSCAM,ECM2,E2F5,AASDH,EBF1,FAM135B,HIPK3,RASGRP1,TMTC1,APH1A,ABI2,ASB3,EIF4G2,DCTN4,USPL1,GPHN,RABEPK,SRRM1,ARMCX1,CHST15,ZNF589,SUCO,AGAP2,SYNCRIP,NELFCD,FOLR2,JKAMP,FAM49B,ATP6V1H,ZNF605,B3GAT1,BRPF3,ARPP21,C15orf41,GATM,TUBGCP4,SULT1C4,CRCP,PRUNE2,CCDC184,CNTRL,RFFL,ADAMTS8,NR3C1,GRM5,GRM7,RNFT2,MAEL,RASSF8,HAS2,MAN1B1,ATXN2L,HMGB1,AGBL5,ZNF491,ZDHHC15,CELF5,FAM95B1,C2orf72,NKD1,IL11RA,LRRTM3,ITGAV,SLC35G1,KCNA1,KCNC2,KCNJ5,KCNN2,STXBP5,LRRC4B,MAT2A,MBD1,AFDN,MXI1,MYO6,NAP1L1,NDUFA5,NEUROD2,ALDH1L2,NME4,NOVA1,NPR2,IGSF11,OGG1,P2RX7,PBX1,ETFRF1,PCDH8,PCSK5,PDE2A,PDGFRA,PFKFB3,SERPINI1,CCSER2,HMGCLL1,ING3,PRKCZ,MAPK9,MASP1,RELN,LRRC49,GDPD2,MDGA2,PIGG,BDNF-AS,PTK2,PTPRB,TUG1,ZDHHC14,BSDC1,RDX,ZYG11B,RET,RFX4,CARF,PCMTD2,UEVLD,ZNF671,MCMBP,ACER3,CNTNAP3,LGR4,KCNIP3,WLS,CLIP1,MIR124-2HG,ELMOD1,SEC14L1,FOXRED1,TRA2B,COPZ1,CPEB3,FNDC3A,ANKRD6,SLC1A7,DHX30,TRIM67,SLCO1A2,MAST1,MBD5,PDZRN3,DOP1A,TNIK,SOX11,CLUAP1,MYCBP2,PEG10,TSPYL2,STOX1,LARP4,NCDN,CEP68,ADHFE1,GSE1,ACSBG1,FGD4,SYNE2,VPS13A,SYP,COBL,ANKRD28,MTCL1,VWA3A,CUX2,TCF7,TPCN2,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,AKNA,TNS2,HIF3A,RNF216P1,DICER1,KHDC1,CRB1,TGFBR3,ZNF106,HHIP,AKTIP,KCTD2,KAT6B,NPL,NR2C2,TUB,ZNF610,AMOT,UGT8,DNAJC12,FLRT1,WIPF1,NSD2,RICTOR,ETNPPL,XPO1,ZBTB14,ZNF24,ZNF28,KCNT2,FMN2,CELF4,PLPPR5,DHX33,WNK1,PRDM2,CSDE1,PCDH15,PPP1R3F,PARP11,PHTF2,ZNF248,SOCS4,JPH3" MicroRNA hsa-miR-431:mirSVR_lowEffct hsa-miR-431:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.57E-122 3.69E-118 6.38E-121 5.88E-120 345 1577 "CLK4,ABHD6,AS3MT,FAM43B,XKR4,KLHL32,ADD2,BRAP,FAHD2CP,BEND6,MTA3,SNX32,KIAA1324,CC2D2A,SPARCL1,CEP126,SYT13,PDZD4,PKP4,APAF1,KCNAB2,APC,ALS2,TNRC6C,USP37,MADD,TMEFF1,CCDC74A,DACT3,NUMB,ASTN1,ATM,ATP2A2,SLC2A11,RNF182,N4BP2L1,NOL4,RGS9,CFLAR,CACNA1G,CA12,CACNG1,CALB1,DIRAS1,CAMK2G,VSTM2A,BRSK2,ISPD,MAP7,RUNX1T1,KRIT1,METTL6,ARHGEF1,C1orf52,SEPT7,REPS2,LRRFIP1,CDO1,IGFN1,SRSF11,CBARP,PLEKHB1,EPS15L1,RAB33A,CLCN4,DGCR9,CLTC,SRP14-AS1,NIPBL,LETMD1,MAGED1,ABI3BP,TBPL1,ZNF521,CHD1L,RBM39,CS,FEZ1,CSNK1G3,GALNT9,PITPNM3,UBXN2A,RUBCN,KATNAL2,DGKB,ARMCX4,ELMO1,CEP170,SMG7,SV2A,NTM,TMCC2,CCDC3,DLG2,DNAH9,RPS6KL1,DRD1,ATN1,DSCAM,ABCC9,EDNRA,FCF1,RASGRP1,SEMA3D,TMTC1,OPTN,SUGP2,EBI3,MBNL2,KMT5B,ABI2,ELAVL2,RGS17,STARD3NL,EPB41,EPB41L1,SLC43A2,SRRM1,EFS,MRPL37,ETV1,RASL12,GMPR2,CLVS1,TMEM132C,PTK2B,ATP8A1,TESK2,PPP1R1B,GTF2IRD2,FGF11,FGF12,FGF14,POLK,SUCO,PCYOX1,ATP13A4,WDR83,SORBS1,TMEM107,CGREF1,ADGRA1,NRG3,GABRB1,CAB39,GAD1,SALL3,ZNF234,IP6K3,WASF3,LRRC37A6P,KIAA1841,ALDH1L1,TCERG1,COPS8,GLYR1,GLS,TOX3,TNRC6A,PCDH11X,STARD3,ZNF638,KDM2B,STON1,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK2,GRM8,RNF165,GSTT2,RNFT2,GUCY1A1,ATOH8,RASSF8,FRMD3,TNFAIP8L3,MIER3,HLF,HMGB1,HMGCL,HMGCR,HNRNPK,ZNF546,USP54,IL6R,OLFM3,KCNA4,KCNJ10,KPNA5,CYP27C1,LIFR,LIMS1,HECTD2,SMAD9,C1orf194,MDM4,MEIS2,SRSF12,MOBP,CD200,DDX25,PABPC1L2A,P2RY13,NELL2,CLEC9A,NUCB2,OLR1,ZNF713,TREM2,PAK3,PBX1,PCDH8,PDE4A,PDE1B,TMOD2,PFKFB2,CDK14,NLGN3,PIK3R1,A2ML1,CCSER2,TMEM38A,ANKRD16,RC3H2,POU3F2,PPARA,PRKACB,PKIA,DIRAS2,BCAS3,GON4L,BDNF-AS,PTN,PTPRB,MARCH1,TMEM255A,CCDC40,RALGDS,SUSD4,NWD1,OXR1,DBX2,KHDRBS2,ZYG11B,ZMAT4,GTDC1,RFX4,ZDHHC4,ZFHX4,ALG9,ROBO1,ROBO2,RPE65,BAALC,ZNF671,SYNDIG1,NCBP3,TMEM156,ATXN2,SCN2B,SCN8A,ELMOD1,HSPA4L,ITSN1,FERMT1,ST6GAL1,WDR37,ARHGEF40,SLC14A1,BTBD7,CPEB4,ZNF667,SMARCE1,ANKRD36,SNCA,SNRPN,KDM4B,PDZD2,FNBP1,ZC3H13,RBM26,NFASC,ITPRID2,SSTR2,NCDN,INKA2,KLHL7,FGD4,JMJD6,SLC37A2,POPDC3,EXOC7,PDLIM2,ANO4,TBX15,WSCD1,ACSL6,TCF4,SIN3B,DMXL2,ZFP90,CUX2,TCF12,WDR7,SYNE1,SLC19A3,OBSL1,PUM2,C18orf54,GALNT17,ARL10,TIAM1,HEY1,TJP1,ZFP91,ERCC6L2,HEY2,TP53BP2,CHST5,ELP5,PPIL6,RUSC1,TTTY15,DNAJC12,MTCH1,VAV2,RBFOX3,KCNT2,ZNF74,MKRN3,CELF4,ANKS1B,LAMP5,LINC02210,HPS4,GAL3ST3,FAM47E,MVB12B,PAK5,KAT6A,NUP214,FAM219B,ZDHHC20" MicroRNA hsa-miR-219-5p:mirSVR_lowEffct hsa-miR-219-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.83E-122 4.40E-118 7.60E-121 7.00E-120 300 1201 "RALGAPA1,CLK4,KDM5D,CSMD3,FMNL2,GALNT13,SLC12A5,SORCS1,GRAMD1B,ZNF608,C1QTNF1,LRRC7,SPARCL1,FAM135A,AMPD3,PHF12,PPFIA2,ANXA7,UPRT,ALS2,LRRC4C,SHTN1,LINC00173,CDK13,CAPRIN2,NUMB,ATP1A2,B3GALT2,DCAF5,BID,FUBP1,SGCE,GPC2,CALB2,PTBP2,CAMK2G,SHISA7,SEPT7,REPS2,LRRFIP1,DLGAP1,CFL2,CHGB,CHM,CHN2,CASC2,CLU,FADS2,NIPBL,CNN3,ARHGEF6,ARMC8,LETMD1,ABI3BP,RTTN,RBM39,ANKRD44,GDA,SNCAIP,LRIG1,SIPA1L1,DZIP3,KIAA0040,UBXN2A,PLCXD3,CTNND2,RIMS2,CX3CR1,DOCK4,GAPVD1,PHF19,PABPC5,DNAL1,ZEB2,FBXL5,MAGI2,G3BP2,WDR20,DOCK2,ACOT8,PDCD6IP,DNAJB6,EDIL3,ATL1,GPR61,MRO,EIF5,EPHA5,DENND4A,F8,ARMCX1,GORAB,FER,OLFM1,POLR1B,FGF12,FHL1,POLK,FOXF2,SYNCRIP,PSD2,AFF2,NOP56,COQ5,ERGIC3,KHDRBS3,STAU2,AP4B1,NRG3,MPP6,PHYHIPL,STAG2,GALNT15,AHCYL1,BRPF3,GALR1,NEK6,NCKAP1,GATM,SRCAP,SULT1C4,MSTN,ADAM28,PCDH17,TCERG1,RAB30,PCDH11X,OS9,FUT10,LILRA1,LILRA2,CNTRL,GRB10,GRIA4,GRM8,RNF165,ADAMTS6,ATOH8,ZHX1,ELOVL5,C2orf72,LRRCC1,HES5,IL6ST,BRINP3,ZNF385B,LRRTM3,NME9,KCND2,KCNJ3,KCNK2,KCNMA1,STXBP5,SYTL4,MAN2A2,LYPLAL1,MAT2A,MBNL1,MEF2C,MEIS1,ADAM22,MT1M,ZC3H12B,NEFM,NHLH1,NODAL,NOVA1,NUCB2,TBC1D25,CHAMP1,PBX1,PCSK5,PDE2A,PDE4D,PFKFB3,PIK3C2A,TMIE,A2ML1,STRN3,LRP12,MINDY2,PPP2R2C,CRLS1,PPP2R5C,PPP2R5E,EPDR1,FITM2,RELN,CNNM2,QRICH1,PIGG,PTN,PTPRN2,FAM120C,TUG1,ZNF844,PPP2R3C,PID1,ZNF793,SLC6A15,RGS12,SEC61A2,SLC25A36,RNASEL,ROBO1,CCDC102B,FBXW7,RXRA,CCDC112,DGLUCY,SAFB,MIR124-2HG,CSRNP3,SCN2A,HES6,SOX6,GALNT10,ITSN1,PPP1R9A,SHC4,FNDC3A,SLC8A2,RADIL,CCDC88A,ZNF667,SMARCE1,IFT122,PDZD2,SOX2,DOK5,ENKUR,UHRF1BP1L,ARHGAP26,KIF1B,RBM26,RAP1GAP2,NFASC,C11orf87,RGL1,STXBP1,GSE1,KLHL7,ZC3H4,PRRC2C,VAMP1,ARHGEF9,VPS13A,TACC1,MCF2L,DNMBP,WWC1,TBL1X,CUX2,ZEB1,RPGRIP1L,SYNE1,OBSL1,PUM2,FRYL,TF,CRB1,AP4E1,TJP1,TK2,TLR4,PRRT1,TP53BP2,NR2C2,RFTN2,UBE2H,FLRT2,TBC1D15,VSNL1,NSD2,SLC13A3,SF1,ZIC3,TCEAL7,CELF4,POLR3H,EML6,ANKS1B,PCBP1-AS1,SMARCAD1,SYNC,MEIS3,INTS3,CSDE1,PRDM8,RNF103,LINC00632,SLC17A6,MVB12B,UBE3B,PAK5,HNRNPA3,KLHDC1,FRMD6,NETO1,CPNE4" MicroRNA hsa-miR-21:mirSVR_highEffct hsa-miR-21:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.76E-122 4.92E-118 8.48E-121 7.81E-120 282 1061 "RALGAPA1,ABAT,KCNH8,C3orf14,TKTL1,FMNL2,ADCY2,CCDC85A,ESYT2,PTCHD1,KIDINS220,DPY19L2P4,NLGN4X,ZNF608,INTS2,CASKIN1,ADGRF5,KIF6,OGT,DPP10,ANK3,LCORL,APAF1,MIER1,PPP4R4,SLC4A4,ATP1B3,ALDH7A1,B3GALT2,N4BP2L1,BCL7A,BLM,ARHGEF7,FUBP1,BTK,MTMR2,PTBP2,KRIT1,RGN,CCPG1,CFL2,SOCS6,CASC2,CNOT8,PLAA,C4orf33,NIPBL,CNTFR,CNTN1,ARMC8,AKAP6,BTF3L4,ABI3BP,PREPL,GDA,TRIM69,SNCAIP,FEZ2,OSBPL3,ATRNL1,SOCS5,DZIP3,KIAA0040,PHF14,ARHGAP32,RIPOR2,ARHGAP24,KCTD8,DGKB,TMEM170A,PABPC5,AIF1L,DNAJC6,COPS7A,MAGI2,ZNF582-AS1,DMD,HS3ST4,DNM2,DTNA,DNM1L,ABCC9,EDIL3,EDNRB,ANKRD46,RASGRP1,FAM13A,PHF20L1,EIF4G1,PLEKHA1,C3orf18,PAN3,ENO2,RCAN2,KCNMB2,NRN1,F3,ARMCX1,FAM198B,ZNF461,SCML2,ST3GAL6,TESK2,KIAA1109,FGF1,POLK,ATP13A4,SGIP1,SORBS1,PDLIM5,TPK1,NPTN,ARFGAP2,NSG2,MSANTD4,STAG2,MEGF11,CHL1,GABRG2,ARPP21,SALL3,NEK6,DISC1,SULT1C4,MSTN,MALT1,PSRC1,DIPK1C,TDRKH,RAPGEF4,GRIA4,RFFL,GRM1,RASSF8,FRMD3,HPSE2,HNMT,HNRNPK,NEGR1,CELF5,SOWAHA,RBPJ,LRRCC1,IL12A,SLC35G1,KCNA2,OLFM3,STXBP5,LAMP2,HECTD2,NCOA7,MATN2,MBNL1,MEIS1,MMP16,MOBP,ZNF680,P2RY13,NELL2,CNTN3,DPY19L2P2,PDE4B,PDGFRA,GNG2,BEST3,ZFYVE21,GPSM2,HMGCLL1,ING3,PACSIN1,PPP3CA,RANBP3L,MAPK10,SAMD9,PTN,TMEM260,PTPRG,PTPRN2,C1orf109,CEP97,RAD51D,RAP1GDS1,ZNF493,ARID4A,MSANTD2,PBRM1,RPRD1A,RAVER2,NEK11,GLDN,PRR5L,ADAL,LRRK2,TRAPPC13,AP1AR,SATB1,LINC00461,FNIP1,SLC30A10,SUPT20H,ITSN1,CPEB3,FBXO11,ST6GAL1,CNKSR2,SLA,ZNF365,BTBD3,SLC8A3,TET1,DMRTC1,RCOR3,LIMCH1,SNAP25,UNC80,USP33,PDZD2,TRERF1,SOX2,SOX5,KDM4C,RBM26,CLASP2,CLSTN2,ITPRID2,MPRIP,DIP2A,KANK1,FGD4,VAMP1,SYT1,C12orf76,ATP11A,CAMTA1,EHBP1,ZFP90,TRIM2,SYNE1,PCDHB4,NSD1,ARHGEF12,CCDC173,CYB561A3,KHDC1,ZFPM2,TIAM1,TIE1,TLR4,ERCC6L2,TMPO,FAM124A,C5orf64,RBFOX2,NPL,ANO5,PRR18,SGK3,CADM1,DNAJC12,ZNF709,CCDC14,VSNL1,LAT2,ZNF708,MICU3,KCNT2,TRIM9,ZBTB16,ZNF189,ANKS1B,PRTFDC1,RNF103,TMEM163,CAB39L,WNK3,EPM2A,DOCK8,RTN4,NUP214,SLC39A12,SSPN,SLC4A10" MicroRNA hsa-miR-30a:PITA hsa-miR-30a:PITA_TOP PITA 9.87E-122 5.54E-118 9.46E-121 8.71E-120 255 863 "ARID1A,CSMD3,SNX30,ADRA1D,LRFN2,AP2A1,AP1B1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,DGKZ,DGKD,USP37,PPP4R4,TMEFF1,CADPS,ATP2B1,ATP2B2,NRP2,BSN,CACNB2,CALB2,SPAG9,SLC5A11,USP6,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,KMT2C,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,SLC4A7,ABI3BP,ZNF521,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,ATRNL1,PLCXD3,CTNND2,FAM131B,DOCK4,TOX,MATR3,MAML1,TOMM20,YTHDC1,JAKMIP2,MYEF2,CEP170,MAGI2,SRGAP3,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,EFNA3,RBM12,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,ELAVL3,EML1,EPB41,EPB41L2,KCNMB2,STX2,EXTL2,ATP8A1,AMOTL2,MEX3B,FOXG1,DACH2,OGA,STAG2,CHL1,GABRB1,TRAF3IP2,JPH4,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,EML4,CECR2,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,DOCK7,JAK1,KCNJ3,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NKX2-2,SMIM11A,NTRK3,OMG,PCDH9,PDE4D,TMOD2,PIK3CD,EPB41L4B,PPP2R5E,CEP41,WBP1L,UHRF1BP1,ELOVL2,PTPN13,PTPRD,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,FIGN,TTLL7,RNF220,SETD5,ALG9,CARF,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,SCN8A,ITSN1,PPP1R9A,PPM1E,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,FHOD3,NLGN1,SLC1A2,FAM81A,WDR47,PKNOX2,SLC6A9,SPHKAP,TET1,CPEB4,SORCS3,TMCC1,ZCCHC24,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,ANO4,TCF4,DMXL2,SATB2,WDR7,SIRT1,TMEM121,TLL2,RIMBP2,R3HDM1,PDSS1,TRPS1,ZMYND8,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,CA10,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,PAK5,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30d:PITA hsa-miR-30d:PITA_TOP PITA 9.87E-122 5.54E-118 9.46E-121 8.71E-120 255 863 "ARID1A,CSMD3,SNX30,ADRA1D,LRFN2,AP2A1,AP1B1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,DGKZ,DGKD,USP37,PPP4R4,TMEFF1,CADPS,ATP2B1,ATP2B2,NRP2,BSN,CACNB2,CALB2,SPAG9,SLC5A11,USP6,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,KMT2C,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,SLC4A7,ABI3BP,ZNF521,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,ATRNL1,PLCXD3,CTNND2,FAM131B,DOCK4,TOX,MATR3,MAML1,TOMM20,YTHDC1,JAKMIP2,MYEF2,CEP170,MAGI2,SRGAP3,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,EFNA3,RBM12,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,ELAVL3,EML1,EPB41,EPB41L2,KCNMB2,STX2,EXTL2,ATP8A1,AMOTL2,MEX3B,FOXG1,DACH2,OGA,STAG2,CHL1,GABRB1,TRAF3IP2,JPH4,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,EML4,CECR2,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,DOCK7,JAK1,KCNJ3,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NKX2-2,SMIM11A,NTRK3,OMG,PCDH9,PDE4D,TMOD2,PIK3CD,EPB41L4B,PPP2R5E,CEP41,WBP1L,UHRF1BP1,ELOVL2,PTPN13,PTPRD,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,FIGN,TTLL7,RNF220,SETD5,ALG9,CARF,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,SCN8A,ITSN1,PPP1R9A,PPM1E,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,FHOD3,NLGN1,SLC1A2,FAM81A,WDR47,PKNOX2,SLC6A9,SPHKAP,TET1,CPEB4,SORCS3,TMCC1,ZCCHC24,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,ANO4,TCF4,DMXL2,SATB2,WDR7,SIRT1,TMEM121,TLL2,RIMBP2,R3HDM1,PDSS1,TRPS1,ZMYND8,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,CA10,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,PAK5,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30b:PITA hsa-miR-30b:PITA_TOP PITA 9.87E-122 5.54E-118 9.46E-121 8.71E-120 255 863 "ARID1A,CSMD3,SNX30,ADRA1D,LRFN2,AP2A1,AP1B1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,DGKZ,DGKD,USP37,PPP4R4,TMEFF1,CADPS,ATP2B1,ATP2B2,NRP2,BSN,CACNB2,CALB2,SPAG9,SLC5A11,USP6,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,KMT2C,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,SLC4A7,ABI3BP,ZNF521,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,ATRNL1,PLCXD3,CTNND2,FAM131B,DOCK4,TOX,MATR3,MAML1,TOMM20,YTHDC1,JAKMIP2,MYEF2,CEP170,MAGI2,SRGAP3,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,EFNA3,RBM12,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,ELAVL3,EML1,EPB41,EPB41L2,KCNMB2,STX2,EXTL2,ATP8A1,AMOTL2,MEX3B,FOXG1,DACH2,OGA,STAG2,CHL1,GABRB1,TRAF3IP2,JPH4,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,EML4,CECR2,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,DOCK7,JAK1,KCNJ3,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NKX2-2,SMIM11A,NTRK3,OMG,PCDH9,PDE4D,TMOD2,PIK3CD,EPB41L4B,PPP2R5E,CEP41,WBP1L,UHRF1BP1,ELOVL2,PTPN13,PTPRD,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,FIGN,TTLL7,RNF220,SETD5,ALG9,CARF,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,SCN8A,ITSN1,PPP1R9A,PPM1E,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,FHOD3,NLGN1,SLC1A2,FAM81A,WDR47,PKNOX2,SLC6A9,SPHKAP,TET1,CPEB4,SORCS3,TMCC1,ZCCHC24,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,ANO4,TCF4,DMXL2,SATB2,WDR7,SIRT1,TMEM121,TLL2,RIMBP2,R3HDM1,PDSS1,TRPS1,ZMYND8,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,CA10,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,PAK5,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30e:PITA hsa-miR-30e:PITA_TOP PITA 9.87E-122 5.54E-118 9.46E-121 8.71E-120 255 863 "ARID1A,CSMD3,SNX30,ADRA1D,LRFN2,AP2A1,AP1B1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,DGKZ,DGKD,USP37,PPP4R4,TMEFF1,CADPS,ATP2B1,ATP2B2,NRP2,BSN,CACNB2,CALB2,SPAG9,SLC5A11,USP6,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,KMT2C,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,SLC4A7,ABI3BP,ZNF521,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,ATRNL1,PLCXD3,CTNND2,FAM131B,DOCK4,TOX,MATR3,MAML1,TOMM20,YTHDC1,JAKMIP2,MYEF2,CEP170,MAGI2,SRGAP3,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,EFNA3,RBM12,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,ELAVL3,EML1,EPB41,EPB41L2,KCNMB2,STX2,EXTL2,ATP8A1,AMOTL2,MEX3B,FOXG1,DACH2,OGA,STAG2,CHL1,GABRB1,TRAF3IP2,JPH4,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,EML4,CECR2,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,DOCK7,JAK1,KCNJ3,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NKX2-2,SMIM11A,NTRK3,OMG,PCDH9,PDE4D,TMOD2,PIK3CD,EPB41L4B,PPP2R5E,CEP41,WBP1L,UHRF1BP1,ELOVL2,PTPN13,PTPRD,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,FIGN,TTLL7,RNF220,SETD5,ALG9,CARF,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,SCN8A,ITSN1,PPP1R9A,PPM1E,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,FHOD3,NLGN1,SLC1A2,FAM81A,WDR47,PKNOX2,SLC6A9,SPHKAP,TET1,CPEB4,SORCS3,TMCC1,ZCCHC24,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,ANO4,TCF4,DMXL2,SATB2,WDR7,SIRT1,TMEM121,TLL2,RIMBP2,R3HDM1,PDSS1,TRPS1,ZMYND8,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,CA10,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,PAK5,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-30c:PITA hsa-miR-30c:PITA_TOP PITA 9.87E-122 5.54E-118 9.46E-121 8.71E-120 255 863 "ARID1A,CSMD3,SNX30,ADRA1D,LRFN2,AP2A1,AP1B1,ZNF608,INTS2,PCDH19,HACE1,TAOK1,SEMA6A,MARCH4,DOC2A,PITPNM2,LRCH2,EPB41L5,DGKZ,DGKD,USP37,PPP4R4,TMEFF1,CADPS,ATP2B1,ATP2B2,NRP2,BSN,CACNB2,CALB2,SPAG9,SLC5A11,USP6,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,KMT2C,NRXN3,CLTC,QKI,MAP4K4,ARHGEF6,CNR1,SLC4A7,ABI3BP,ZNF521,SLC35F1,PNKD,CLOCK,NCOR2,GDA,OSBPL3,ATRNL1,PLCXD3,CTNND2,FAM131B,DOCK4,TOX,MATR3,MAML1,TOMM20,YTHDC1,JAKMIP2,MYEF2,CEP170,MAGI2,SRGAP3,CPEB2,SLC12A6,DPYSL2,RCAN1,MAMLD1,EDNRA,EFNA3,RBM12,YAF2,CELSR3,FAM13A,MBNL2,EGR3,KCTD3,ELAVL3,EML1,EPB41,EPB41L2,KCNMB2,STX2,EXTL2,ATP8A1,AMOTL2,MEX3B,FOXG1,DACH2,OGA,STAG2,CHL1,GABRB1,TRAF3IP2,JPH4,IP6K3,GATM,GCNT2,PCDH17,PPARGC1A,TTBK1,GLDC,DBF4,GLI2,TNRC6A,GNAO1,ADGRA3,EML4,CECR2,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,MIER3,HLF,ELOVL5,SMAP1,DOCK7,JAK1,KCNJ3,CAMK2N2,LIFR,MARK1,MAT2A,CHIC1,MEIS2,KITLG,MYO5A,PABPC1L2A,NAP1L1,NCAM1,NEFM,NEUROD1,NF1,NKX2-2,SMIM11A,NTRK3,OMG,PCDH9,PDE4D,TMOD2,PIK3CD,EPB41L4B,PPP2R5E,CEP41,WBP1L,UHRF1BP1,ELOVL2,PTPN13,PTPRD,USP47,RALGDS,OXR1,ARID4A,REV3L,PRRT2,FIGN,TTLL7,RNF220,SETD5,ALG9,CARF,SEMA6D,SBF1,ATXN1,SCN2A,SCN3A,SCN8A,ITSN1,PPP1R9A,PPM1E,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,FHOD3,NLGN1,SLC1A2,FAM81A,WDR47,PKNOX2,SLC6A9,SPHKAP,TET1,CPEB4,SORCS3,TMCC1,ZCCHC24,SOX11,KDM3A,SP4,HECW1,CDK19,NKAIN2,STAU1,ZSCAN29,RGL1,STXBP1,SYN2,SYPL1,TACC1,CAMTA1,ADGRL3,ANO4,TCF4,DMXL2,SATB2,WDR7,SIRT1,TMEM121,TLL2,RIMBP2,R3HDM1,PDSS1,TRPS1,ZMYND8,MICAL1,TBC1D15,WIPF1,CLDND1,XPO1,PCDH20,ZNF711,MKRN3,REEP1,ZFAND5,CA10,SLC30A4,MAP3K12,EVI5,STOX2,ADAMTS9,URM1,MARCH8,PAK5,HNRNPA3,PHTF2,FRMD6,RNF146,GAN" MicroRNA hsa-miR-190:mirSVR_highEffct hsa-miR-190:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.87E-122 5.54E-118 9.46E-121 8.71E-120 299 1194 "KLHL32,SLITRK1,PTCHD1,DPY19L2P4,ZNF608,KLHL13,TBC1D14,NME5,OSBPL6,HFM1,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APAF1,GPAM,TNRC6C,MIER1,CASK,NCOA1,NUMB,ASTN1,ADGRB3,LINC00847,SEC11C,DST,SYNJ1,SCAPER,CA8,CACNA1D,HIP1R,CBLN1,CDC42,CDH18,CLGN,COPB2,RCBTB2,CASC2,NDST3,NRXN3,PLAA,NRXN1,CNN3,BTF3L4,COL9A2,ZFP28,CPS1,CLOCK,HAPLN1,ANKRD44,SEC24C,ATRNL1,SOCS5,PDE4DIP,APPL1,RIMS2,BOC,RIPOR2,DCAF8,ZEB2,MYEF2,CEP170,MAGI2,AK5,G3BP2,DMD,DMTF1,DRP2,PDCD6IP,DTNA,ECM2,EDIL3,EDNRA,RASGRP1,SEMA3D,RBM12,PHF20L1,AASS,KCTD3,ELAVL2,PLEKHA1,DCTN4,ENPP6,GPHN,NCALD,CEP85L,ETV1,SIRPB1,GMPR2,CLVS1,ABCA8,SH3YL1,TAOK3,CEP78,FKTN,FDFT1,SLC9B2,FGF14,FHL1,MEX3B,NBEA,UFM1,ATP6V1H,ATP2C1,ZNF605,DACH2,STAU2,NRG3,PHYHIPL,ZMAT1,MEGF10,CAB39,ZMYND11,RAPGEF6,ARPP21,GALR1,SALL3,IQGAP2,C15orf41,KIAA1841,PCDH17,PPARGC1A,MALT1,GK,RND1,CRCP,GLRB,TOX3,TNRC6A,PCDH11X,DCLK2,PRUNE2,PCLO,GRIA4,GRIK3,GRM5,GRM7,AP4S1,PSIP1,GUCY1B1,GYG1,HAS2,MIER3,ELOVL5,ZDHHC15,NEGR1,SMAP1,IRF8,IFI16,ZIC5,PLD5,ITGAM,KCNA4,KIF5C,STXBP5,LIMS1,HECTD2,NCOA7,LYPLAL1,MATN2,MATN3,LRP1B,MID1,POC1B,ZNF680,MRPL42,BLOC1S2,BCO1,C10orf105,MYO9A,NCAM2,NEK1,NEUROD1,NF1,LRIT2,NRCAM,HCN1,GPR137C,PAH,CNTN3,PAX6,ETFRF1,PCDH9,PDE3B,PDPK1,GNG2,BEST3,OLA1,ZNF655,PLCL1,TRHDE,EPB41L4B,MED1,PPP2R2C,PPP2R5C,PPP2R5E,PPP3CB,GRAMD1C,DIRAS2,LRRC49,SIDT1,BDNF-AS,PTHLH,PTN,TMEM260,SUSD4,ZYG11B,ERI2,RPRD1A,C12orf49,BAALC,ATP8B4,GLDN,ACER3,CNTNAP3,RYR3,TRAPPC13,ATXN7,SCN7A,LINC00461,FNIP1,TNFRSF19,SEC14L1,TRA2B,SH3GL2,FNDC3A,FHOD3,NLGN1,CTXN2,BTBD3,RUFY2,SEPHS1,SLC14A1,SLC15A2,ZFP1,RCOR3,UNC80,TNIK,HECW1,MYCBP2,KDM4C,MCF2L2,RBM26,LARP4,NKAIN2,NXT2,RGL1,KLHL7,SYT4,EXOC7,ANO4,SATB2,TCF12,WASHC4,DOCK9,TEX15,FAM200B,SIRT1,CRB1,ITGB3BP,AP4E1,SLC44A1,ERCC6L2,FAM124A,BEX4,RIMBP2,CSMD1,TPD52,PRMT8,AMACR,STXBP4,ZMYND8,PPIL6,TSC1,CADM1,OSBP2,P2RY12,ZIC3,ZNF708,TRIM9,CELF4,ZBTB16,ZSCAN26,PLPPR5,ZFAND5,CA10,MAP3K12,PRDM2,CSDE1,ADAMTS9,CIAPIN1,PCDH15,NAV3,C12orf4,RNF170,SSPN,FRMD6,GAN,SENP7" MicroRNA hsa-miR-541:mirSVR_lowEffct hsa-miR-541:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.14E-121 6.38E-118 1.09E-120 1.00E-119 360 1713 "ASPHD1,ASIC2,FMNL2,ADARB2,TMEM132B,GALNT16,TMCC3,ADD1,PLEKHH1,AP2A2,SPOP,CEP126,SYT13,AMPD2,ZFAT,ANK1,FGD2,CCDC146,LCORL,DGKZ,DGKD,PHYHD1,AMER3,TNRC6C,PPFIA3,USP37,PRX,MADD,SPTBN4,ZFYVE28,ARHGDIA,MARCH3,CCDC74A,ASPH,NUMB,DYNLL1,TMEM108,ATP1A2,CADM3,ATP6V0A1,RIPK1,RGS9,BCL7A,CFLAR,KSR1,CDK5R1,LINC00906,C1QC,MYRF,CFAP410,CACNA1A,DDR1,CACNB2,KALRN,HAP1,RUNX1T1,CBS,SHISA7,USP2,ENTPD6,KCNAB3,CCPG1,NUMBL,CACNA2D2,FOXN3,CHGA,ASIC3,CASC2,SYNPR,TAOK2,DLGAP3,RAB33A,CLTC,NGEF,DNAJB5,IGLON5,CNR1,PCYT1B,FAM149A,LETMD1,COL11A2,ABI3BP,CP,ZNF385A,PNKD,ABCG1,AATK,SNCAIP,SEC24C,FEZ1,MICAL2,SLITRK5,GREB1,CYBB,MYADM,PHF19,TM9SF4,INTS1,PHYHIP,PITPNC1,CEP170,SPOCK3,NTM,TMCC2,SEC16A,SLC29A4,DNM2,DPH1,DPYSL2,ABI1,TOM1,DYRK1A,AASDH,EFNB3,MBNL2,TNK2,ELN,EN2,EPHA5,RABEPK,SPEG,CDHR1,NRN1,TUBB4A,CHST15,FCGRT,STRADA,ZNF589,SLC9B2,FGF13,TMEM164,POLK,RGPD5,ERGIC3,B3GAT1,TPPP3,B4GALNT1,DISC1,SEPT9,ATP8A2,LRRC37A6P,CYP46A1,GFER,KIRREL3,TNRC6A,MSL3,PCDH11X,OS9,GNAO1,GNAS,GNG3,PRUNE2,GPM6B,TMEM121B,STMN2,GRIA1,GRIA4,GRID1,RFFL,SPACA9,ADAMTS13,GRIN1,GRIN2D,GRM2,GSN,GSTM5,AP4S1,RABL2A,UBE2QL1,HPS5,PADI2,HRH3,HAPLN2,AGBL5,LRRC75A,SHISA6,CELF5,SMAP1,MSL1,IDH3B,RBPJ,KIAA1755,TMEM240,LRRTM1,NME9,KCNA6,KCNJ11,KCNK1,KCNK3,KCNMA1,KHK,LINC00634,IPO5,LRRC4B,STMN1,LMO1,NCOA7,CLEC18A,MAN2A2,MATN2,MEST,MGAT3,AFDN,MOBP,GIT1,MSI1,MT3,MTTP,LYRM9,MYO7A,RTL5,FXYD6,NF1,DNHD1,PCBP3,NRGN,NTRK3,NUCB2,GPR88,PAK3,CDK18,PDE4B,BEST3,PFKFB4,ZDHHC8,PIK3R1,FAM218A,KCTD15,PLEC,PLXNB3,PNMA3,C11orf49,PRRX1,NECAB2,FAT3,POLR2F,FSD1,PPARA,PPP3CA,NKAIN4,CEP41,RAB39A,MASP1,NDUFS7,WBP1L,LRRC49,UHRF1BP1,FAM120C,ZSCAN2,TMEM231,RAB3A,CCDC40,RAP1GAP,RAP1GDS1,ENOX1,ZNF493,OXR1,RASGRF1,RASGRF2,DBX2,VEPH1,TRIM68,RFX4,KIF7,RNH1,ARMC5,ROBO2,STK32B,WLS,RYR3,DGLUCY,SEMA6D,IL17RB,PEAR1,TRIM46,GALNT10,MRAS,SH3BP2,ITSN1,FAM102A,MAGI3,FHOD3,DZIP1,ZNF365,FAM81A,RPH3A,SMTN,SLC6A8,SLC8A3,SLC11A1,KBTBD4,EPC1,CXXC4,SMARCD3,RIMS1,SNAP25,FAM126B,DOP1A,KIF21B,SOX10,ZSWIM8,IDI2-AS1,SPTAN1,DDN,NFASC,ATP10B,CLSTN2,ITPRID2,LARP4,SSPO,STX1A,SYT11,ARHGEF9,ADAMTS17,COBL,EXOC7,ADGRL3,TMEM136,KIAA0930,SZT2,AZIN2,TMEM151B,PCDHB15,OBSL1,ARHGEF12,PUM2,TNS2,AHCYL2,HIF3A,CYB561A3,DICER1-AS1,TIAM1,CABIN1,RASD2,NPL,TRPM2,DCBLD1,RUSC1,CLHC1,SLC35A4,CLEC2L,GORASP1,ZNF709,BCL2L13,MEAF6,CLIP2,CLDND1,NPDC1,ZSCAN26,FTSJ1,ZNF213,MAP3K12,ITM2C,WIPF2,UBE3B,FBXO36,CASC15,CAMK1G,RNF146,LAS1L" MicroRNA hsa-miR-3182:mirSVR_highEffct hsa-miR-3182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-121 8.63E-118 1.47E-120 1.35E-119 312 1301 "VWA5B2,NCKAP5,GPRIN1,CSMD3,BRAP,PLEKHH1,GRAMD1B,PWWP2A,PTCHD1,KIDINS220,AP2A2,KCTD16,SPARCL1,SPOP,FAM135A,ZFAT,EP400,LCORL,USP28,PKP4,APC,BCAS1,TNRC6C,SHROOM2,MIER1,ARNTL,ASPH,INSYN2B,EIF4G3,ATP1B3,ATP2B1,ALDH7A1,NOL4,ADAM23,MPDZ,CFLAR,NAE1,KALRN,VSTM2A,CAST,RUNX1T1,LDB2,CBFA2T2,ENTPD6,DGKI,CDH2,LRRFIP1,CACNA2D2,SRSF11,CHN1,SLIT2,CLTC,AKAP7,IQCK,COL4A5,COL9A1,SLC4A8,AHCTF1,TOGARAM2,MYRIP,CHD1L,ANKRD44,GDA,TENM4,ARHGEF10,PHACTR3,UBXN2A,ARHGEF4,CTNND2,PUM1,RIMS2,PPP6R2,CCDC144A,CYBB,HDAC9,DCAF8,FRMPD4,MATR3,DGKG,SMG7,DLG2,GRIN3A,HS3ST4,NYAP1,DNAH9,DMTF1,CASP8AP2,DTNA,MAMLD1,ABCC9,E2F6,PHC2,FCF1,RASGRP1,FSD1L,RBM12,PHF20L1,EGR3,ELAVL3,EML1,RCAN2,LRRC17,EPHB1,GPHN,RABEPK,SRRM1,CEP85L,CDHR1,ETV1,RTN3,RCSD1,MRVI1,CLVS1,FCGR1A,CEP78,CHST15,FDFT1,PRMT5,GORAB,SUCO,CAP2,SEMA4D,SLC37A3,JKAMP,HVCN1,FAM49B,ATP2C1,ABLIM2,ZMAT1,MEGF11,GALNT15,ILDR2,AHCYL1,JPH4,RAPGEF6,NEU3,TUBGCP4,GGTA1P,GHR,MALT1,BRD8,TCERG1,GLS,ZNF638,INSM2,LILRB4,PRUNE2,GPR19,MCHR1,EML4,ATP2B1-AS1,GRIA2,GRIK2,GRM1,PRDM5,GRM7,ZNF496,TMEM25,KAT7,AP4S1,MAP4K5,FRMD3,CELF5,ZNF385B,KCNK2,KTN1,INSYN2,PAXBP1,PACRG,MAOB,MAT2A,MDM4,MEST,PPM1L,MYH3,LYRM9,NEK1,NFE2L2,NODAL,CNOT4,NPPA,CLEC9A,OGG1,OPA1,PAK3,CDK18,PDGFRA,A2ML1,JAKMIP1,MED1,PRKACB,EPDR1,FITM2,GRAMD1C,DIRAS2,PROX1,DCHS2,RELN,SIDT1,PTCH1,MTMR10,ELOVL2,EML5,STRC,MARCH1,DBX2,FEZF2,RBBP8,ZDHHC14,SLC6A15,ZYG11B,DUSP15,RIT2,RIC8B,RPRD1A,ZFHX4,TMLHE,ALG9,RAVER2,CARF,ELP2,CCDC102B,ACER3,ZNF331,SCN8A,CASC3,SUPT20H,NLGN4Y,ZFP30,MAGI3,FBXO11,ZNF365,CPEB4,SORCS3,SMARCE1,ANKRD36,RIMS1,MBD5,NMNAT2,KDM4C,RBM26,TAB2,ZNF302,ELOVL4,ADHFE1,GSE1,KLHL7,ARHGEF9,ANKRD28,ANKRD12,EXOC7,TBCEL,FBXW11,ATMIN,VWC2,TCF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,FAM200B,ITGB3BP,HHIP,SLC44A1,TIMP4,ASXL3,BHLHB9,ZFP91,ERCC6L2,TMOD1,TPM1,TPM4,ZNF346,ZMYND8,TMPRSS5,LRTM2,SGK3,UGT8,PLEKHH2,P2RY12,ZNF781,RICTOR,GUSBP1,CFAP298,KCNT2,ATP6V0E2,TCEAL7,ZBTB16,ZNF213,UPF3A,EMSY,LRP8,STOX2,RNF103,PCDH15,KCNAB1,C12orf4,PDSS2,FZD3,MARCH8,KAT6A,CASC15,TRAM2-AS1,ZDHHC20,FRMD6,DPF3,JPH3" MicroRNA hsa-miR-20b*:mirSVR_lowEffct hsa-miR-20b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-121 9.44E-118 1.60E-120 1.48E-119 328 1435 "ABAT,ABR,ACADM,ACHE,ACTN1,GALNT16,PWWP2A,SNX30,ZNF608,SNX32,RTL9,NME5,CC2D2A,TAOK1,ALCAM,BCAR3,LTBP4,GOLGA7B,AMPD2,AMPD3,MAP4K3,PHF12,APBA2,CACHD1,USP37,SEMA4G,NOL4,DPY19L3,TTLL9,BACH1,BCHE,DNAJC27-AS1,CDK5R1,SYNJ1,SCAPER,IL33,CACNA1B,PTBP2,CAMK2G,VXN,VSTM2A,SPAG9,RUNX1T1,METTL6,REPS2,LARGE1,CCPG1,NUMBL,CACNA2D2,SRSF11,B4GALT6,RAB28,NRXN3,NRXN1,QKI,NIPBL,CNN3,AKAP7,ARMC8,AKAP6,LETMD1,SLC35F1,CRY2,GDA,AATK,SNCAIP,SEC24C,FEZ2,LRRC3B,MICAL2,OSBPL3,VCAN,PDE4DIP,CYBB,EARS2,ZNF337,KIF26A,DGKB,DGKG,PABPC5,SPATA2,ZEB2,RABGAP1L,DLG2,RAB39B,DMD,DNM1,NR1D2,DNM2,SLC12A6,CASP8AP2,DNAJB6,DYRK1A,GOLT1B,E2F5,WDPCP,EDNRA,EDNRB,RASGRP1,MRO,MBNL2,GOLGA7,EIF5,PLEKHA1,MRNIP,PAN3,DCTN4,RCAN2,KCNMB2,STX2,EFS,RCSD1,CLVS1,ZIC4,SCML2,ATP8A1,MEX3B,PCYOX1,SYNCRIP,FLT1,SLC37A3,SORBS1,SMC2,ATP2C1,PNMA2,AP4B1,STAG2,GAB1,GABRB3,ZNF274,IQGAP2,ERAP1,DISC1,KIAA1841,DNER,WASHC2A,AHDC1,GGT7,GHR,PPARGC1A,GK,TCERG1,DBF4,CBX1,LUZP2,RAB40B,GNAS,PSRC1,LILRA1,STON1,GRIA1,ADAMTS13,NR3C1,GRM1,BTN2A1,FAM19A2,TMEM25,AP4S1,PSIP1,NXPH3,PTGDR2,ARHGAP19,ELOVL5,HNF4G,LRRC75A,HTR2A,ZIC5,IL6ST,KCNJ3,KIF2A,STXBP5,HECTD2,ARHGAP12,GPR155,MAT2A,MBD1,MEF2C,SRSF12,WDR49,MOBP,ERICH3,MRPL42,MSR1,MSRA,MYO5A,NEXMIF,MYT1,NAP1L1,NAP1L2,NDUFA5,NF1,NFE2L2,NFYA,CLEC9A,NUCB2,P2RX7,SNTG1,CNTN3,BEST3,PFKFB3,OLA1,PIK3C2A,MAGEL2,SPATA6,POLG,TATDN3,PPP3CB,PKN2,GDPD1,CNNM2,GON4L,NCR3LG1,TMEM260,ZIK1,FAM120C,PTX3,RAD51D,ATG16L1,RAP1GDS1,ENOX1,ZYG11B,ERI2,GTDC1,RFX4,RIT2,SEC61A2,PBRM1,ZNF532,TMLHE,ALG9,CARF,GSTCD,RORB,UEVLD,FBXW7,BAALC,ZC3H14,TCP11L1,RPS20,ATAT1,S100B,DGLUCY,SEMA6D,SATB1,ATXN7,SCN2B,LINC00461,SCP2,TRIM46,TRA2B,ITSN1,SH3GL3,PPM1E,CPEB3,MYO18A,SHC4,FBXO11,R3HDM2,ANKRD6,NUBPL,PAAF1,BTBD3,WDR47,CCDC88A,SLC11A1,SLC12A2,SLC14A1,ELMO2,ATF7IP,KIF13A,TMCC1,PDZD2,SOX15,SP2,ZSWIM8,NMNAT2,KDM4C,ERC1,KIF1B,ZBTB43,SPART,LMO3,CLASP2,STOX1,STAU1,SEPT3,GSE1,FAM208A,TMEM136,TBX15,ACSL6,VWC2,DMXL2,SATB2,TCF12,SZT2,SYNE1,C18orf54,AP4E1,SLC44A1,ARL10,BEX4,TP53BP2,STXBP4,ANO5,TST,TUBB1,RPRM,UGT8,PITPNB,OSBP2,ZNF709,NSD2,RICTOR,ZIC2,MICU3,KCNT2,PLPP4,ZNF154,ANKS1B,WNK1,EVI5,STOX2,NAV2,UBE3B,JMJD1C,FXR1,SENP7" MicroRNA hsa-miR-378b:mirSVR_lowEffct hsa-miR-378b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-121 1.31E-117 2.21E-120 2.04E-119 339 1531 "SERPINA3,CLK4,SYS1,KDM5D,GPRIN1,ADAR,ADCY2,ADCY6,CCDC85A,TMCC3,ADD2,ADD3,ADORA1,ADORA2A,RNF150,KIDINS220,MTA3,SNX32,PCDH19,SPARCL1,GPRASP2,AMPD2,CDC42BPA,APBA2,KCNAB2,VAT1L,ARNTL,MARK4,CAPRIN2,ASPH,NUMB,N4BP2L1,MIR9-3HG,DNAJC27-AS1,KSR1,GYG2,CACNA1G,MMD2,CFAP410,KALRN,PTBP2,CAMK2A,VXN,SYT6,CBS,CCNH,CBFA2T2,ENTPD6,ZBED1,DCLK1,GPR37L1,SOCS6,CASC2,PPT2,MYL6B,NMT2,FHL5,IQCK,COL4A5,ABI3BP,MFSD4A,CHD1L,CLOCK,HAPLN1,CRYM,SNCAIP,ATRNL1,NCAN,CNTNAP2,PPP1R16B,UBXN2A,ZSCAN23,EDRF1,CCDC144A,ARHGAP32,HDAC4,IST1,SIRPA,SPATA2,DNAJC6,ZEB2,TMEM130,SV2B,SGSM2,WDR20,ZNF582-AS1,DLG2,DLX1,OLIG1,DOCK2,DMTF1,PDCD6IP,EDN1,FAM135B,SGK2,RASGRP1,SUGP2,MBNL2,SORBS3,IRAK4,PLEKHA1,TMEM35A,EN2,VPS13B,SEZ6,NCALD,ZNF549,CDKL3,SIRPB1,MRVI1,ZNF461,PTK2B,CEP78,ZSCAN30,SEC24B,MED12L,FGR,SUCO,PCYOX1,AGAP3,PSD2,ZCCHC17,APOPT1,KBTBD12,B3GAT1,SARAF,NRG3,DKK3,CAB39,FAM184B,GALC,RAPGEF6,IP6K3,GAP43,DISC1,INPP5K,SRCAP,GPR162,GGTA1P,TTBK1,CRCP,ZNF638,CBX1,DCLK2,GPM6B,RAPGEF4,GRIK2,GRM7,CLASRP,IL1RAPL1,BVES,LINC01102,ZDHHC15,LRRC75A,CELF5,IDH3A,NKD1,KNDC1,TJAP1,LIX1,IL6R,TMEM240,KCND1,KCNJ3,KCNJ10,KCNN3,KLC1,L1CAM,HECTD2,MAT2A,AQP11,SYT9,AFF1,CCDC80,MSR1,MSRA,PTOV1,MYO7A,RTL5,HNRNPM,NCF2,NELL1,VWA2,DNHD1,CLEC9A,NTRK3,NUMA1,GPR88,PCDH9,PDCD2,PDE4A,PDE1B,GPR173,TMOD2,PFKFB4,NLGN3,ZNF655,CCSER2,XRN1,FTO,MTRF1L,CDIP1,RC3H2,PPM1B,CRLS1,PPP3CA,VSTM2L,RASGEF1B,MAPK4,MAPK9,GRAMD1C,HYDIN,PEX2,PEX5,NWD1,RAP1GDS1,RASGRF1,ERI2,PRIMA1,KCTD17,RNF220,CARF,GSTCD,PCMTD2,SNX22,NEK11,RPL15,SPIN3,KIAA0895L,GLDN,TCP11L1,SYNDIG1,ABCA11P,HSD11B1L,AP1AR,MAPK12,SOX6,CASC3,ZNF821,PPP1R9A,NTNG1,MAGI3,ANKRD6,PAAF1,EPN2,SLC6A1,PKNOX2,LRRC55,SLC8A2,SLC8A3,ARHGEF40,SLC20A2,SPHKAP,CXXC4,SNRPN,PDZRN3,DOP1A,PDZD2,WDTC1,SOX3,ZCCHC24,BDP1,NMNAT2,UHRF1BP1L,SPTAN1,TSPYL2,RBM26,NFASC,LHPP,ITPRID2,SMOC1,SSTR1,LARP4,ZSCAN29,ADHFE1,STX1A,ARHGEF9,SYN2,MMS19,TACR1,MCF2L,DNMBP,FBXW11,ANO4,TBX15,SIN3B,TCF7,TCF7L2,TCF12,WDR7,AKNA,TEK,FAM200B,ZNF34,FBXL16,ARL10,TNFRSF1B,PRRT1,PIK3R5,TPM4,RGMB,NR2C2,SYNPO2,AMACR,TRPC1,DCBLD1,RUSC1,ANO5,RFTN2,CLHC1,SGK3,USP1,CCDC14,WIPF1,KLC2,RICTOR,SLC47A2,SF1,KCNT2,LYPD6,SH3GLB2,FTSJ1,MFF,PRDM2,PRDM10,RNF103,HPS4,CIAPIN1,SIGLEC10,DOCK8,UBE3B,HNRNPA3,FBXO36,NUP214,VANGL2,SSPN,SLC4A10,FAM198A,JPH3" MicroRNA hsa-miR-4297:mirSVR_lowEffct hsa-miR-4297:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.52E-121 1.41E-117 2.39E-120 2.20E-119 344 1575 "KCNH8,ACHE,KLHL32,TMEM132B,ADCY6,TMCC3,GRAMD1B,USP31,KIAA1211,SLC24A4,PCDH19,KIAA1324,DISP3,CC2D2A,ZNF578,ALAD,ALCAM,CEP126,MARCH4,DPP10,PPFIA4,PHF12,PKP4,CASK,ASPH,DACT3,RASL11B,ATP1B3,DPY19L3,RIPK1,LINC00847,CFLAR,SYNJ1,JAZF1,GYG2,GPC2,BTRC,CACNA1E,CACNB4,CABP7,CAMK2A,CAMK2B,HIP1R,PRC1,LDB2,CD86,ARHGEF1,SYNGR3,MAGI1,DLGAP1,CFL2,ZBED5,LSMEM2,RAB28,NRXN2,STOML1,TMEM155,BTF3L4,CP,PNKD,PREPL,C2CD2,C1QL2,GDA,CLIP3,SNCAIP,CSF1,TENM4,LRIG1,FEZ1,MICAL2,ATRNL1,SIPA1L1,CHD5,CST3,PITPNM3,SDC3,RIMS2,RUBCN,SEC14L5,HDAC9,ARHGAP32,KATNAL2,LIN54,AIF1L,HEPH,KIAA0753,COPS7A,DDX46,SV2B,SV2A,CCDC3,DLG2,DNM1,USP3,CDON,DOCK2,DMTF1,DPH1,DPP6,ACOT8,DTNA,EDNRA,ANKRD46,PHF20L1,KMT5B,TMEM35A,EPHB1,RABEPK,EFS,ZNF549,DNAJC27,ECSIT,TBC1D16,ATP8A1,FCGR1A,CEP78,ZSCAN30,FGF1,FGF12,HPCAL4,AGAP3,NELFCD,EFCAB2,JKAMP,TMEM107,UFM1,NSG2,ST6GALNAC3,HHIPL1,MPP6,ILDR2,BRPF3,RAPGEF6,ACSS1,IGSF5,ALDH1L1,GHR,MALT1,ZNF276,GLI2,GLYR1,MSL3,KDM2B,DCLK2,WDFY3-AS2,FUT10,MCHR1,GPR37,GRM7,LINC01089,CLASRP,KAT7,ZBTB49,LINC01551,ATOH8,HAS2,TOX2,FRMD5,PTGDR2,GABARAPL2,AGBL5,CPT1C,HTR2A,ATCAY,ZNF546,LRRCC1,DISP2,SCIN,IL6R,INPP5B,ITPKB,KCND2,KCNJ9,KCNK1,KCNK3,KCNN1,KIT,KLC1,LAMP2,MAPT,KCTD6,XRRA1,MOV10,ERICH3,JAKMIP3,MT3,RSPO2,HNRNPM,NHLH1,NODAL,LRIT2,NUCB2,NUMA1,TBC1D25,OGG1,OPCML,ZNF827,ZDHHC22,PRTG,PDE3B,BEST3,PFKFB2,PFKFB3,GDAP1L1,A2ML1,SNX10,PLXNB3,PNMA3,SPATA6,EPB41L4B,NXPH1,PPARA,MED1,PPP1R1A,PTPA,PPP2R5E,PRKAB2,PRKACB,PRKCZ,DIRAS2,MASP1,VPS13C,PTPRD,PTPRN2,ACSM5,NKAIN1,TUG1,TMEM231,C1orf54,FAT4,NWD1,ROGDI,OXR1,RASGRF2,ZDHHC14,RGS12,ARHGEF10L,ZFHX4,ZNF532,CARF,CYB561D1,CCDC102B,EPHA10,MAP6D1,LGR4,HUNK,ST6GALNAC6,KCNIP3,RYR3,SCP2,GALNT10,MRAS,RASA3,ITSN1,SH3GL3,FRMPD1,CPEB3,MYO18A,NTNG1,FBXO11,FNDC3A,ST3GAL3,PPP4R3A,PKNOX2,LRRC55,SLC6A11,SLC8A1,SLC11A1,SLC15A2,SCMH1,NAXD,SMARCC2,CDK5RAP2,MBD5,KIF13A,SNRPN,PALLD,TMCC1,UNC80,SON,NMNAT2,CLUAP1,ZC3H13,KIF1B,NFASC,CLSTN2,STOX1,ZC4H2,LRRC4,ZSCAN29,STAC2,STXBP1,SYT11,FGD4,SYN1,ANKRD28,SLC37A2,SYT5,EXOC7,UNC5D,CNTN2,ATMIN,RPGRIP1L,TCF12,WDR7,PCDHB10,OBSL1,TNS2,FRYL,AHCYL2,HIF3A,PMS2CL,AP4E1,TMEM9,C5orf64,TP53BP1,SYNPO2,NEIL2,FNDC5,KCNE5,UBE3A,UBTF,UGT8,PITPNB,OSBP2,PLEKHH2,WIPF1,ZNF781,RICTOR,GUSBP1,PCDH20,ZBTB16,TMEM237,AMZ1,PRDM2,PARP6,URM1,UBE3B,HNRNPA3,CAMK1G,ZNF248,PIANP,SPATA13" MicroRNA hsa-miR-3142:mirSVR_lowEffct hsa-miR-3142:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.27E-121 1.84E-117 3.10E-120 2.86E-119 318 1354 "ABAT,ABR,ASIC1,ABHD6,EMILIN3,SYS1,ACTN2,ADCY2,ADD2,BRAP,SORCS1,GPR158,HECW2,PCDH19,CC2D2A,HFM1,CEP126,C6orf89,USP28,SUGT1P4-STRA6LP-CCDC180,ALS2,VAT1L,TMEFF1,ASPH,PCDHGB4,INSYN2B,TMEM108,EIF4G3,ATP2B2,ATP2B3,AZGP1,LINC00847,FGF17,SYNJ2,FUBP1,CFAP410,CACNA1D,KALRN,SYT6,CCKBR,P2RX6,DGKI,CDC25B,CDC27,ASIC3,MS4A7,NDST3,RAB28,FBXO7,TMEM184B,SRP14-AS1,WHRN,SLC25A27,SLC4A8,ZNF521,CNRIP1,MFSD4A,NECTIN3,SLC35F1,SEC31B,RBM39,CRY2,SNCAIP,CSF3R,FEZ1,PLXNA4,FAM169A,SLITRK5,KIAA0040,CMTM5,ECE2,CYBB,BOC,ARHGAP32,DCAF8,FRMPD4,IST1,HEPH,CEP170,TMEM130,SGSM2,RAB39B,NR1D2,SLC12A6,DPH1,ACOT8,ATN1,TOM1,ABCC5,EDNRB,ANKRD46,FSD1L,SIDT2,EFNB3,EGFR,GOLGA7,ELAVL4,CALCRL,VPS13B,SPEG,DNAJC27,FCGR1A,FCGR1B,KAT8,UBE2E3,MEX3B,PCYOX1,SYNCRIP,IQCG,FLT1,ARFGAP2,CELF1,KBTBD12,FYN,MEGF10,GABRG1,BRPF3,B4GALNT1,JPH4,ZNF559,SEPT9,LRRC37A6P,GCNT2,GFAP,HEPN1,LYVE1,GJB1,DHRS4,TTBK1,GLI2,GLS,AIFM3,DCLK2,NUDT21,GPR37,CECR2,CNTRL,GRID1,RFFL,GRM1,ZNF496,CLASRP,ZBTB49,ATOH8,FAM222A,HAS2,ZHX1,ELOVL5,SYNPO,AGBL5,ZNF491,AGFG1,LRRC75A,RAB41,ZIC5,KCNA1,CDH20,KCND1,KCNJ11,KCNK1,KHK,KTN1,INSYN2,LIMS1,LMO2,GPR155,MAP2,MAT2A,MBD1,SYT9,MDM4,LRP1B,MMP16,MOBP,ADAM22,MXI1,MYO6,MYT1,ZC3H12B,VWA2,CNOT4,NPTX2,SLC11A2,NUMA1,IGSF11,OMG,LOC100128398,P2RX7,PCDHGC3,PCSK2,PFKFB3,GPSM2,NLE1,PLXNB3,ING3,SPATA6,TNPO2,NXPH1,CEP41,MASP1,SLC22A23,QRICH1,CNTLN,PTHLH,RAB3IL1,CCDC40,FAM66C,SH3TC2,RASGRF2,RBBP6,HKR1,CRTAC1,RET,ERI2,RGS4,RGS10,ARHGEF10L,SLC25A36,RIC8B,CCDC82,CCDC25,ROM1,ELP2,LRRK2,LGR4,MEG3,ZNF568,ZNF331,MAPK12,CSRNP3,ATXN2,SMPD3,PEAR1,SOX6,GALNT10,ITSN1,CPEB3,FUZ,DZIP1,ANKRD6,NUBPL,WDR37,SLC1A7,SEPHS1,SLC8A1,RAB3GAP1,SLC8A3,SLC9A5,SMARCC2,CDK5RAP2,ANKRD36,INAVA,KIF13A,SNRPN,UNC80,SOX11,SP4,KDM4C,UNC5B,DDN,LHPP,C11orf87,ITPRID2,MPRIP,CEP68,SEMA4A,EXOC7,UNC5D,TBL1X,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,AKNA,PCDHA5,HIF3A,KCTD2,C5orf64,KAT6B,PIK3R5,TP53BP2,NPL,TPM2,PRMT8,FNDC5,RUSC1,TMEFF2,FAM155A,EIF4ENIF1,BEST1,ZNF781,XPO1,ZNF24,TRIM9,FMN2,POLR3H,DPYSL5,PMEPA1,EMSY,FAM47E,MVB12B,PDSS2,UBE3B,PAK5,CAMK1G,SSPN,LAS1L" MicroRNA hsa-miR-562:mirSVR_lowEffct hsa-miR-562:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.07E-121 2.29E-117 3.85E-120 3.55E-119 346 1595 "CLK4,PSMG3-AS1,ADCY6,CCDC85A,AXIN2,SORCS1,BEND6,RTL9,OSBPL1A,OSBPL8,TXNDC16,CC2D2A,SPARCL1,ALCAM,ARHGAP20,AMPD3,CCDC146,USP28,ANXA7,DDO,PPFIA3,APP,SHROOM2,CASK,TMEFF1,CDK13,CCDC74A,NCOA1,ATP2B1,ADGRB3,BBS2,KSR1,DST,SCAPER,JAZF1,CACNA1I,CACNA1G,LDLRAD4,CACNA1B,SPAG9,RUNX1T1,CBR1,USP6,CBFA2T2,DGKI,LRBA,CDC42,CDH8,ZMYM4,NUMBL,CASC2,ARHGAP22,PLAA,TPP1,TMEM59L,AKAP5,SLC4A7,ABI3BP,MYRIP,CNRIP1,CHD1L,FAM171B,AKAP12,ANKRD44,GDA,SNCAIP,CSF2RA,FEZ1,LRRC3B,PHACTR3,USP6NL,CCDC144A,GPRASP1,FRMPD4,ZFYVE16,EARS2,GIT2,PITPNC1,ELMSAN1,C8orf34,ZEB2,HEPH,MYEF2,FBXL5,ZC3H11A,KBTBD11,DLG2,GRIN3A,DMD,HS3ST2,RPS6KL1,DYNC1I1,DPP6,SLC25A18,DRP2,DTNA,AASDH,WDPCP,FAM135B,SEMA3D,ABI2,PLEKHA1,USPL1,EPB41L1,LRRC23,ENPP6,EYA1,AMZ2,TUBB4A,FKTN,KAT8,GTF2IRD2,FGF13,FGF14,UBE2E3,HPCAL4,PCYOX1,FOXO3,SEMA4D,NOP56,WDR83,SORBS1,ATP2C1,ERGIC3,KHDRBS3,STAU2,TBR1,DOT1L,NRG3,STAG2,GAB1,CHL1,DENND2A,GAD2,GALC,B4GALNT1,JPH4,NCKAP1,ERAP1,DISC1,KIAA1841,GATM,IGSF5,GBX2,SULT1C4,MSTN,CSDC2,GGTA1P,GJB1,MSL3,GNAL,FERMT2,PRUNE2,GPM6A,NUDT21,GRM1,KAT7,SLC2A6,HPS5,FRMD3,SYNPO,HMX1,HNMT,ZDHHC15,FAM95B1,IGFBP1,TJAP1,USP54,SCIN,IL6R,IL11RA,BRINP3,DIPK1A,ITPKB,KCNC2,KCNJ16,KCNK1,KLRC3,STXBP5,KTN1,STMN1,MAOB,MBNL1,IL17D,LAYN,FXYD6,NCAM1,NEUROD1,SLCO1C1,TBC1D25,OPHN1,PAH,CNTN3,PCMT1,PDE4B,PDE4D,PDGFRA,SLC10A4,CAMKV,NOMO2,ZNF655,CCSER2,RETREG1,XRN1,FTO,PLIN1,PCDH18,ZNF426,PURG,PDZRN4,TRHDE,MBOAT7,FA2H,NXPH1,SH3KBP1,PPM1B,PPP3CB,KANSL1,RASGEF1B,RAB39A,MAPK9,VPS13C,LRRC49,ANKHD1,PTN,TMEM260,STK32A,PTPRH,PTPRO,FAM120C,CEP97,PLEKHB2,FAT4,RBBP6,ZDHHC14,MSANTD2,RDX,GAL3ST4,SLC6A15,ZYG11B,RFX4,RGS12,MRPS18A,RIC8B,RPRD1A,EXD2,TMEM100,ARMH4,ZC3H14,ATP8B4,ACER3,FAM161B,SOX8,WLS,CLIP1,NCBP3,CCDC112,SATB1,ATXN2,FNIP1,SOX6,FRMPD1,FERMT1,MYO18A,NTNG1,FNDC3A,NLGN1,PAAF1,ZNF365,PEX26,SLC8A1,ARHGEF40,ZKSCAN3,SNAP25,MBD5,SNRPN,SON,PDZD2,SOX3,PEG10,NPAS3,TROVE2,ITPRID2,STOX1,NKAIN2,INKA2,CEP68,KANK1,GSE1,PRRC2C,SYNE2,DNAJC9,SYT4,CAMTA1,UNC5D,FBXW11,KLHL4,EHBP1,ACSL6,TRIM2,SYNE1,PHF24,PCDHB15,RALYL,FRYL,AHCYL2,TEX15,DNAH7,ZFPM2,AKTIP,SLC44A1,ARL10,GZF1,TIAM1,ACTR6,DDHD1,BHLHB9,NPL,CHST5,SYNPO2,TRPS1,TMEFF2,AMOT,UGT8,DNAJC12,USP1,VLDLR,RICTOR,XPO1,SF1,ZNF24,KCNT2,ELFN1,FSTL5,EML6,DPYSL5,SPIRE1,SLC30A4,SLC38A1,TMEM178A,KCNAB1,DNAH10,AMN1,UBE3B,CASC15,LAS1L" MicroRNA hsa-miR-606:mirSVR_lowEffct hsa-miR-606:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.07E-121 2.29E-117 3.85E-120 3.55E-119 318 1355 "SYS1,CSMD3,TMCC3,ADD1,PLEKHH1,USP31,BEND6,KLHL13,OSBPL1A,TBC1D14,OSBPL8,ZNF578,LRRC7,DPP10,USP28,GPAM,CACHD1,USP37,AQP4,CDC14B,TMEM263,TMEFF1,ARHGAP5,ARNTL,NUMB,ATM,SLC4A4,BACH1,MPDZ,BMPR1B,ARHGEF7,NAE1,SCAPER,MTMR2,JAZF1,CACNB2,CACNB4,CAMK2D,MTMR7,AIFM1,C1orf52,LRBA,REPS2,CDH2,DCLK1,ZMYM4,LGI1,DLGAP2,SRSF11,CHN2,SYNPR,CNOT8,JAM2,RAB28,DGCR9,CLTC,QKI,COL4A5,SLC4A7,ABI3BP,RCHY1,ACBD5,FAM171B,CREM,AKAP12,RNF14,TRIM69,SNCAIP,OSBPL3,DOCK4,FGFR1OP2,GAPVD1,ZFYVE16,TBC1D5,DGKB,DAPK1,AIF1L,YTHDC1,DNAJC6,C8orf34,MYEF2,MFAP3L,HP1BP3,FBXL5,MAGI2,SMG7,SV2B,DLG3,DMTF1,ARRDC4,ABCC5,GOLT1B,E2F5,FAM135B,HIPK3,RASGRP1,SEMA3D,RBM12,YAF2,SH3GLB1,EFNB3,PHF20L1,APH1A,EGFR,ABI2,ASB3,EIF5,COPS4,C8orf37,EPHA5,ENPP6,NCALD,KATNAL1,NSRP1,FABP7,ACSL4,ATP8A1,SUCO,MEX3B,PCYOX1,ANKFY1,SLC37A3,C2orf88,ATP6V1H,DACH2,OGA,GABRB1,GABRB3,GABRG1,GAD2,ZNF234,SIGLEC8,DNER,FAXC,PCDH17,DBF4,GLS,KIAA1958,LUZP2,PRUNE2,GPM6B,STON1,RAPGEF4,GRIA2,GRIA4,GRID1,NR3C1,GRM2,GRM7,BTN2A1,HLF,HMGB1,SCRG1,LRRC75A,SHISAL1,LRRCC1,LIX1,IL6ST,ITGAV,METTL21A,KCNA4,KCNJ3,KIF5A,STXBP5,SYTL4,HECTD2,CHIC1,LDLRAD3,KCTD6,KITLG,ERICH3,MYCN,NEXMIF,NAP1L2,ZC3H12B,NEUROD1,NF1,ALDH1L2,NOVA1,SLC11A2,NTRK2,GPR88,OPA1,PBX1,PCSK2,BEST3,SERPINE2,PIK3R1,CCSER2,TRHDE,CDIP1,DRAM2,CRLS1,PPP3CA,PRKACB,PKN2,GRAMD1C,MDGA2,QRICH1,CNTLN,TMEM260,STK32A,PTX3,STRC,NWD1,ERI2,RGS12,SEC61A2,RIC8B,RNASEL,ZFHX4,CCDC82,RORB,RPE65,RPL15,ZNF671,MCMBP,ACER3,CNTNAP3,LGR4,RTN1,SALL1,SEMA6D,CSRNP3,LRRTM4,TNFRSF19,GALNT10,SUPT20H,PPM1E,FERMT1,NTNG1,CHD9,FBXO11,CNKSR2,SEC31A,NUBPL,PREX2,LRRC55,SLC8A1,SLC12A2,NAPB,SLC15A2,CPEB4,CXXC4,RCOR3,IGSF9B,MBD5,SNRPN,FAM126B,SOX2,ZCCHC24,SOX11,SP4,RBM26,NPAS3,C11orf87,SULF2,VAMP1,SYPL1,COBL,TAC1,ZEB1,TPCN2,TRIM2,CLASP1,AZIN2,SYNE1,DOCK9,PCDHB3,NSD1,ARHGEF12,PUM2,GPRIN3,TEX15,DICER1-AS1,ZFPM2,CRB1,ZNF106,TMEM9,DDHD1,C5orf64,RBFOX2,RGMB,STXBP4,TRPS1,ANKRD20A2,TTTY15,ZKSCAN5,CLHC1,UBE3A,PLEKHH2,TBC1D15,ZNF24,ZNF45,FMN2,GPR158-AS1,LYPD6,REEP1,DPYSL5,ANKS1B,SPIRE1,SYNC,UPF3A,CADM2,PRDM2,LRP8,EVI5,RNF103,WNK3,MVB12B,PDSS2,UBE3B,HNRNPA3,ADAMTSL3,TIGD6,DPF3,SOCS4,SLC4A10" MicroRNA hsa-miR-892b:mirSVR_lowEffct hsa-miR-892b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.25E-121 3.51E-117 5.90E-120 5.43E-119 347 1606 "ABAT,ABR,NCKAP5,ADD1,PTCHD1,OSBPL8,DISP3,CC2D2A,AK2,LRRC7,SPOP,ARHGAP20,GOLGA7B,ZNF687,ANK3,LCORL,ARMC12,MYH7B,PPFIA1,SEMA4G,ASCL1,DNAH17,DACT3,CHRD,CCAR2,DDX3Y,TMEM108,ATP1A2,EIF4G3,ALDH7A1,DPY19L3,BACH1,PROM1,SYNJ1,LINC00906,GYG2,CA12,CACNA1E,DDR1,CACNB2,CALM1,KALRN,CCNH,SEPT7,REPS2,CDC25B,DCLK1,FOXN3,SOCS6,MS4A7,RAB28,CLTA,CLTC,TJP2,ABCG2,SRP14-AS1,RAB26,SUMF2,FAM171B,CLOCK,HAPLN1,GDA,CRYM,CSF1R,SEC24C,PDE4DIP,CST3,KIAA0040,CFAP61,DCAF4,HDAC9,RIPOR2,TOX,ZNF337,TBC1D5,LIN54,ARMCX2,SPATA2,JAKMIP2,ZEB2,HEPH,FBXL5,COPS7A,KIAA0319,KLHL3,SMG7,RABGAP1L,FAM107B,RAB39B,OLIG1,USP3,NR1D2,DMTF1,DYRK1A,DNM1L,EBF1,EDNRA,HIPK3,APH1A,MBNL2,KMT5B,EIF4G2,SORBS3,ELN,EPHA5,PIPOX,DNAJC27,CEND1,ADGRV1,FAM198B,PTK2B,TOMM40L,STRADA,TESK2,FECH,SPSB4,IP6K2,SEMA4D,NOP56,NELFCD,CGREF1,OGA,MEGF11,DKK3,MEGF10,GABRA2,GABRA3,DENND2A,BRPF3,FAM120B,ZMYND11,GALC,B4GALNT1,RAPGEF6,ZNF274,GAP43,INPP5K,GATM,PCDH17,GGT7,ZNF276,GLYR1,PCDH11X,POLL,NUDT21,GRB10,GRIA1,GRIA4,GRID1,GRIK2,SERP2,GRIN2C,AP4S1,RNFT2,ADAMTS6,SLC2A6,PADI2,FRMD5,PTGDR2,ARHGAP19,HMGB1,GABARAPL2,AGBL5,HSD17B1,MSL1,C5orf24,LRRCC1,SCIN,IL11RA,ITPKB,JAK2,KCNA1,KCNH1,KCNJ10,KCNN2,KCNN3,KIF5C,A1BG-AS1,STMN1,C2orf80,MAP6,MARK1,MARK3,MATN3,LDLRAD3,MEF2C,SRSF12,MID1,PPM1L,POC1B,ERICH3,ZNF680,GIT1,RSPO2,MXI1,MYH6,LAYN,RTL5,NELL1,DNHD1,PCBP3,SLC11A2,OPHN1,ZNF827,PBX1,PCDH9,PDE2A,PDE3A,PDE4D,PDGFRA,SEMA5B,PLCD1,PLIN1,PRIMPOL,PNMA3,C11orf49,ANKRD16,CDIP1,SCHIP1,PRRX1,ING3,TATDN3,PTPA,PPP2R5C,PPP3CA,RASGEF1B,GRAMD1C,SIDT1,GDPD2,CNTLN,PTCH1,ANKHD1,PTK2,TMEM260,ZSCAN32,PTPRE,FAM120C,ZSCAN2,TUG1,RALGDS,RAP1GDS1,RASGRF2,FEZF2,GAL3ST4,ZYG11B,PRIMA1,PBRM1,RNH1,MYH14,CARF,GSTCD,YY1AP1,ELP2,TRAPPC13,AMER2,FOXRED2,SEMA6D,HOGA1,SCN7A,PRCD,TNFRSF19,CASC3,TRA2B,COPZ1,PPP1R9A,SH3GL3,SHMT2,MAGI3,NLGN1,CTXN2,SEC31A,DZIP1,WDR37,ABLIM3,LRRC55,SLC6A8,KBTBD4,SLC15A2,ATF7IP,SORCS3,CDK5RAP2,CABCOCO1,PALLD,PDZRN3,SON,SOX5,SPATA7,KIF21B,KIF1B,NFASC,TAB2,CLASP2,POGZ,ZNF302,ZC4H2,SEPT8,CEP68,NSFL1C,ZFR2,ATP11A,KAZN,ROBO3,DNMBP,FAM208A,TMEM136,ANO4,TCF12,WDR7,FRYL,SIK3,TEK,FAM200B,CRB1,CDH22,ARL10,ENHO,MTMR14,TIMP4,TLL2,TMOD1,RBFOX2,SYNPO2,TRO,RUSC1,CADM1,GORASP1,FRRS1L,PITPNB,BCL2L13,WIPF1,ZNF24,GPR158-AS1,LYPD6,SPIRE1,PMEPA1,EVI5,PRDM8,PRDM10,RNF103,GAL3ST3,KCNAB1,MPPE1,AMN1,NUP214,MSRB3,FXR1,IFT88" MicroRNA hsa-miR-548a-3p:PITA hsa-miR-548a-3p:PITA_TOP PITA 8.58E-121 4.82E-117 8.09E-120 7.45E-119 249 828 "KCNH8,CSMD3,FMNL2,ADCY2,CCDC85A,USP31,NLGN4X,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,LRRC7,AMPH,CDC42BPA,ALS2,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,DDX3Y,SLC4A4,ATP2B1,N4BP2L1,ADGRB3,CDK5R1,SYNJ1,ARHGEF7,FUBP1,NIPA1,WASF1,CACNB4,CALB1,CALM1,PTBP2,CANX,RUNX1T1,SEPT7,CDH10,CLGN,NOG,SRSF11,SOCS6,LHX2,NRXN2,CLTC,FAM19A5,QKI,NIPBL,BAG4,ACBD5,CLOCK,CDC42BPB,CREM,CREB5,CRMP1,ATRNL1,ERC2,PLCXD3,CTNND2,ST18,HDAC4,LONRF1,MATR3,DGKB,TOMM20,MYEF2,ZC3H11A,DDX46,G3BP2,FAM107B,DMD,USP3,DSCAM,DYRK1A,HIPK3,RBM12,EFNB3,KMT5B,ABI2,EIF4G2,ELAVL2,STARD3NL,EIF1,EPB41L1,TAOK3,ATP8A1,FGF13,FGFR3,SUCO,FOXO3,FAM49B,DACH2,B3GAT1,STAG2,GABRB1,GABRB3,GABRG2,HBS1L,MSTN,AHDC1,MMADHC,GLS,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,PTPN5,SOX21,PSIP1,GYG1,BACH2,MIER3,HLF,NEGR1,SMAP1,BRINP3,LRRTM3,KIF2A,KIF5C,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,NFIA,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,CDK14,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,POU3F2,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,FAM120C,TTC13,RAB5B,PID1,CEP97,ARID4A,RBBP8,RADX,ZYG11B,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,ATXN1,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,WDTC1,SOX1,MYT1L,ZCCHC24,SOX11,SOX15,LMO3,SRPK2,TAB2,CLASP2,EPB41L3,SS18,ERBIN,ST5,RGL1,PLCB1,SYT4,ANKRD12,CAMTA1,CAMSAP2,WWC1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,RALYL,TMEM121,ZFPM2,TGFBR3,SLC44A1,DDHD1,TLR4,ERCC6L2,KCNE5,TUB,TUBB2A,RPRM,AMOT,FLRT2,WIPF1,NSD2,ZBTB14,ZNF711,ZFAND5,SMARCAD1,WNK1,CA10,PMEPA1,EMSY,CSDE1,STOX2,NAV3,SNX27,KCNAB1,PCBP4,WNK3,PDSS2,GOPC,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-590-5p:mirSVR_lowEffct hsa-miR-590-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-120 5.72E-117 9.58E-120 8.83E-119 334 1495 "ACLY,GALNT13,ADRB2,HECW2,ALCAM,PCDH10,FAM135A,GPRASP2,SYT13,SEMA7A,USP28,PKP4,EPB41L5,GPAM,APOC1,CDC14B,MIER1,SLC7A14,PDXK,ASCL1,STK33,ASPH,NUMB,TMEM108,RNF182,DOCK11,TTLL9,ADGRB3,BCHE,DCAF5,SYNJ1,NAE1,CACNA1G,NIPA1,CACNA1E,CACNG1,THSD7A,KALRN,SPAG9,CBR1,LGI1,L3MBTL4,CDO1,COPB2,RAB28,ZFYVE9,CLTC,CNN3,FAM149A,AKAP5,ACBD5,MYRIP,HS3ST5,CHD1L,SEC31B,AKAP12,RNF14,ANKRD44,LRRC3B,CSNK1G3,SDC3,APPL1,PLCXD3,NRSN1,RUBCN,NOS1AP,HDAC9,TCAF1,ZFYVE16,TBC1D5,LIN54,MATR3,KCTD8,SCRN1,ARMCX2,MFAP3L,MAGI2,DDX46,POM121,RHOBTB1,SPOCK3,SV2A,DLG2,DLX1,HS3ST2,MED12,DMTF1,SLC12A6,ACOT8,PDCD6IP,ECM2,DNAJB6,ABCC5,E2F5,SNX29,FAM135B,ATL1,FRY,OPTN,RBM12,EGFR,MBNL2,EIF4G1,COPS4,USPL1,RCSD1,ATP8A1,FCGR1A,FECH,SLC9B2,MED12L,PRKAG2,SUCO,FOXG1,SYNCRIP,FOXM1,FOXO3,ANKFY1,SLC37A3,NBEA,STAMBP,KHDRBS3,DACH2,CSPG5,B3GAT1,HRASLS5,TRAF3IP2,HBS1L,RAPGEF6,C15orf41,GATM,GCNT2,FREM1,GGTA1P,GLYR1,MSL3,GLUL,ZNF638,FERMT2,ADGRA3,STON1,GPR34,PCLO,GRM7,BTN2A1,BVES,AP4S1,TMEM179,HAS2,ZHX1,BACH2,HMGCR,EID2B,MSL1,ZIC5,LRRCC1,USP54,ZNF678,ITGAM,CDH20,KCND2,KCNJ3,KCNJ10,KCNK1,KCNK2,VWA5A,PACRG,MBD1,MBP,CHIC1,SHC3,MEF2C,MEIS2,KCTD6,MOG,MSR1,TMEM249,RSPO2,LAYN,MYO6,MYO9A,NAP1L3,NCAM1,NEK1,NFIA,ALDH1L2,NOVA1,NTRK2,OXTR,KCNK10,PAK3,PC,ETFRF1,PCDH8,PCSK2,PDE3A,PDE4D,PDPK1,PFKFB2,SERPINI1,PIK3C2A,FAM218A,RETREG1,PLP1,SLC25A23,PMP2,LRP12,MBOAT7,POU3F2,IRX1,MINDY2,PRKAB2,RASGEF1B,PRKCB,PKN2,MAPK9,GRAMD1C,CNTLN,PTK2,PTPN13,OCIAD1,PTX3,TUG1,FAM66C,ZCWPW1,RBBP6,ZDHHC14,BSDC1,RDX,RET,ERI2,FIGN,RGS10,SEC61A2,TMLHE,PNMA8A,CCDC102B,LRRK2,ZNF568,CCDC112,CSRNP3,LRFN5,SCN7A,SCN8A,SOX6,KIF21A,SH3GL3,SHC4,NLGN1,CTXN2,DZIP1,WDR47,LRRC55,SLC6A11,KBTBD4,BTBD7,ZFP1,CDK5RAP2,ANKRD36,MBD5,SNRPN,SOX1,FNBP1,GLT8D1,HECW1,UHRF1BP1L,ZBTB43,RBM26,TAB2,SSTR2,ELOVL4,CEP68,PHLDB1,STXBP1,KLHL7,NECAB1,JMJD6,PLCB1,SYPL1,DDHD2,CNTN2,TMEM136,ANO4,TCF4,RPGRIP1L,WDR7,RALYL,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA3,PCDHA2,PCDHA1,RNF216P1,CRB1,AP4E1,ZMAT3,TGFBR3,ZNF106,ACTR6,HEY2,CSMD1,TP53BP2,METTL3,STXBP4,SSBP2,CLHC1,TMEFF2,SLC35A4,CLDND1,SLC13A3,XPO1,MICU3,FMN2,ZNF74,ZBTB38,REEP1,FSTL5,EML6,SMARCAD1,INTS3,CADM2,SHD,SLC38A1,FAM47E,KAT6A,SMIM8,RNF170,SLC39A12,FXR1,NETO2,SLC4A10,JPH3" MicroRNA hsa-miR-1248:mirSVR_highEffct hsa-miR-1248:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-120 5.98E-117 1.00E-119 9.21E-119 332 1478 "RALGAPA1,TTYH1,NCKAP5,NDRG2,RNF157,ADD2,SORCS1,PTCHD1,CC2D2A,AK2,ADGRF5,FAM135A,AMPD3,AMPH,DPP10,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,TNRC6C,API5,USP37,ASPH,DACT3,CCAR2,ATP1A2,STX16,ADAM23,RGS9,SYNJ2,GPC2,CA8,DDR1,CACNB2,KALRN,PTBP2,VXN,RUNX1T1,CBR1,CCNT1,MTMR7,CD81,LRBA,CDC42,MS4A7,B4GALT6,ZBED5,JAM2,NDST3,PLAA,CLCN3,NRXN1,CLTA,VAX2,DNAJB5,NIPBL,IQCK,WHRN,SLC25A27,AHCTF1,MFSD4A,SLC35F1,SEC31B,ANKRD44,SNCAIP,RGS6,FEZ2,FEZ1,CSNK1G3,GALNT9,PDE4DIP,CNTNAP2,PLXNA4,ECE2,CCDC144A,CYBB,DOCK4,HDAC9,MYADM,FGFR1OP2,GAPVD1,CENPL,MATR3,BRINP1,ALKBH8,SMG7,SV2B,DLG2,DLX1,DMD,CPEB2,DMTF1,PDCD6IP,DTNA,ABCC5,ABCC9,FCF1,SYT15,FSD1L,PHF20L1,PLEKHA1,DCTN4,EN2,RCAN2,EPHA5,SRRM1,IGSF6,EYA1,F5,ZIC4,TAOK3,SCML2,DLC1,FCGR1A,ST3GAL6,CEP78,FGF1,FGF12,FGF13,FGFR1,POLK,SYNCRIP,NOP56,NELFCD,C2orf88,AKAP3,SMC2,UFM1,CAMKK2,PRELID3A,STAU2,ZNF512,ZMAT1,GALNT15,GABRG2,TRAF3IP2,GAD1,GAD2,AHCYL1,BRPF3,JPH4,C15orf41,DISC1,MYOZ2,GCNT2,SULT1C4,WASHC2A,CYP46A1,ADAM28,PCDH17,PPARGC1A,GK,POLL,TDRKH,STON1,PCLO,ADAMTS8,CLASRP,RNF165,TMEM25,AP4S1,MAP4K5,MAEL,ZHX1,NXPH2,ARHGAP36,HMGB1,HNF4G,NEGR1,HTR5A,IRF8,IL12A,INPP5B,KCND1,KCNK1,KCNK2,CREG2,KTN1,LAMP2,INSYN2,SYTL4,HECTD2,PIK3AP1,SYT9,MDM4,MMP16,WDR49,MRPL42,SCG3,LAYN,ZNF862,NDUFA5,NF1,NINJ2,CNOT4,NOVA1,NRCAM,NUCB2,GPR88,OGG1,OLR1,OXTR,PAK3,PRTG,PDE3B,PDE1B,PDYN,GPR85,CDK14,TMIE,XRN1,FAM216A,PRRX1,POLG,NXPH1,MED1,CRLS1,PPP2R5C,KANSL1,PRKCZ,PROX1,LRRC49,SIDT1,SNRK,CNTLN,BDNF-AS,TMEM260,ZSCAN32,FAM120C,ENOX1,OXR1,RASGRF2,DBX2,RDX,ERI2,RFX2,RFX3,RFX5,RIT2,RIC8B,CCDC102B,NEK11,RPL15,FBXW7,SPIN3,ACER3,CCDC112,GALNT10,NLGN4Y,SCG5,ITSN1,SH3GL3,ASAP3,CPEB3,NTNG1,FHOD3,NLGN1,SLA,RUFY2,LRRC55,SLC6A11,RAB3GAP1,SLC8A3,SIRT2,SLC14A1,ATF7IP,TET1,DMRTC1,SNCA,SON,BDP1,SP4,CLUAP1,MYCBP2,KDM4C,ZC3H13,CDK19,NPAS3,ATP10B,TROVE2,SSTR2,TTBK2,SULF2,FGD4,VPS13A,NUDT10,C12orf76,ATP11A,CAMTA1,TAF9,EXOC7,ANO4,TBX15,SZT2,DOCK9,RALYL,PCDHB10,GPRIN3,FRYL,FAM200B,CRB1,ITGB3BP,SLC44A1,TIAM1,MTMR14,BHLHB9,ZFP91,ERCC6L2,SYNPO2,TRPS1,ANKRD20A2,SGK3,AMOT,ZNF45,AGMO,LYPD6,ZNF184,LRP8,RNF103,ADAMTS9,NAV3,PPP1R3F,FIP1L1,CAB39L,PCBP4,WNK3,PDSS2,FAM13C,UBE3B,HNRNPA3,CASC15,JMJD1C,TRAM2-AS1" MicroRNA hsa-miR-141*:mirSVR_highEffct hsa-miR-141*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-120 6.89E-117 1.15E-119 1.06E-118 311 1302 "RALGAPA1,KCNH8,NCKAP5,ADD3,SORCS1,OLMALINC,CC2D2A,SPOP,ALCAM,FAM135A,AMPD3,AMPH,OGT,PPFIA1,UPRT,ALS2,SHTN1,PPP4R4,MADD,ZFYVE28,DACT3,BBS2,PROM1,DST,ARHGEF7,FUBP1,LINC00906,BTK,PTBP2,CANX,CAST,ZNF501,USP6,AIFM1,C1orf52,SEPT7,CDC42,ZMYM4,CDO1,CDR1,CIART,SYNPR,JAM2,LHX2,KMT2C,IGFBP7-AS1,ZFYVE9,NRXN1,ABCG2,QKI,MAP4K4,CNR1,IQCK,BTF3L4,SLC4A8,AHCTF1,CP,CHD1L,C2CD2,CREM,RBM39,CRMP1,HAPLN1,ABCG1,ARHGEF10,SLITRK5,PHF14,CTH,CFAP61,ZSCAN23,TCAF1,FRMPD4,ZFYVE16,ACY3,KCTD8,TMEM170A,BRINP1,DBI,GIT2,SIRPA,DCC,ALKBH8,RHOBTB1,DLG2,USP3,DMTF1,PDCD6IP,RCAN1,ANKRD46,PHF20L1,EGFR,GOLGA7,KCTD3,C8orf37,MRVI1,NRN1,DLC1,CEP78,CHST15,FDFT1,KIAA1109,POLK,SEMA4D,NOP56,SMC2,UFM1,PDLIM5,ST6GALNAC3,GABRA2,HRASLS5,ILDR2,HBS1L,GALC,GALR1,DISC1,MYOZ2,NEU3,ADAM28,GGT7,GHR,LYVE1,GK,SPIN1,TNRC6A,PCDH11X,ZNF638,INSM2,LUZP2,ADGRA3,GPD2,NUDT21,GPR37,GRIA4,GRM5,FRMD3,DDX19B,ATXN2L,HMGB1,SYNPO,HMGCR,HSP90AA1,SMAP1,IRF8,SCIN,IL6R,IL6ST,ZNF678,ZNF385B,KCNH2,KCNK2,KCNN2,CREG2,STMN1,LIG4,MARK1,MATN2,MBD1,LRP1B,KCTD6,MOBP,MOG,ERICH3,MSR1,BEX5,SFR1,NEK1,NF1,SLCO1C1,NOVA1,HCN1,TREM2,PAK3,ETFRF1,PDYN,GPR85,ZNF655,FAM218A,SNX10,RETREG1,PLIN1,HMGCLL1,MTRF1L,PSAT1,SLC36A4,PPP2R5E,PRKAB2,PRKCG,MAPK4,EPDR1,GRAMD1C,MASP1,KLK6,CNNM2,NDUFS7,VPS13C,SIDT1,MDGA2,TMEM260,PTX3,TMEM255A,SH3TC2,C1orf54,ZCWPW1,OXR1,RASGRF2,TRIM68,MORC4,RGS12,TTLL7,RPRD1A,CCDC82,ROBO2,ELP2,NEK11,BAALC,ACER3,TCP11L1,RPS6KA2,PTGR2,WLS,KCNIP1,AMER2,ATXN2,FAM19A1,SGK1,NTNG1,SHMT2,CHD9,PAAF1,WDR47,RAB3GAP1,BTBD7,ATF7IP,SPHKAP,SLC22A4,RCOR3,ANKRD36,LIMCH1,MBD5,CMTR2,PALLD,SON,BDP1,GLT8D1,CAND2,ZBTB43,TAB2,SAMSN1,ERBIN,ZSCAN29,TTBK2,AJAP1,FGD4,VPS13A,PLCB1,SYN2,SYT1,DDHD2,DNMBP,TAL1,CAMSAP2,UNC5D,ANO4,RPGRIP1L,WDR7,SYNE1,FRYL,AHCYL2,PMS2CL,CRB1,C18orf54,ITGB3BP,AKTIP,FBXL16,TMEM9,CDK20,PRMT8,TSC1,CLHC1,RPL7L1,UBE2H,UGT8,PITPNB,PLEKHH2,MEAF6,ZNF781,NSD2,XRCC4,MICU3,KCNT2,ZNF540,GPR158-AS1,SLC26A10,MKRN3,POLR3H,ZSCAN26,ZNF189,MEIS3,PRDM2,TMEM178A,DNAH10,FAM13C,CASC15,ADAMTSL3,KLHDC1,NETO2,NETO1,DPF3,SLC4A10,GAN,SENP7" MicroRNA hsa-miR-625:mirSVR_lowEffct hsa-miR-625:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.51E-120 8.46E-117 1.41E-119 1.30E-118 340 1549 "TTYH1,CLK4,EMILIN3,SYS1,CSMD2,GPRIN1,ADAR,GALNT16,RNF157,OLMALINC,NLGN4X,C1QTNF3,CARNS1,UNC79,BEGAIN,AMT,DPP10,CCDC146,CPNE5,ARHGAP5,LINC00173,MARCH3,NUMB,ATP2B3,N4BP2L1,ATP6V1G2,TTC9B,HCN2,PROM1,SYNJ2,ARHGEF7,CACNA1I,CDK5R2,CALM1,PTBP2,NGB,VSTM2A,HIP1R,CBLN1,METTL6,USP2,SYNGR3,LGI1,CASC2,TAOK2,DLGAP3,EPS15L1,NRXN1,CLTA,CLTC,ABCG2,MAP4K4,HOMER3,IGLON5,AKAP5,ZNF385A,CPS1,PNKD,SEC31B,AKAP12,GDA,SEC24C,CSF3R,ATRNL1,IPCEF1,PDE4DIP,PITPNM3,SDC3,PHF14,PLCXD3,CX3CR1,HDAC9,MYADM,SNPH,PHF19,KIAA0513,PHYHIP,SPOCK2,GIT2,SPATA2,DCTN1,PLEKHM1,CNIH3,KLHL3,BLOC1S6,POM121,SPOCK3,SGSM2,ARNT2,DPP6,DPYSL2,ACOT8,DRP2,MAMLD1,ABCC5,PHC2,CNNM1,SEMA3D,TMTC1,PHF20L1,SUGP2,EGFR,MBNL2,ABI2,EGR3,AASS,GOLGA7,EIF1,EPB41L1,COQ7,DMTN,EPHB1,DENND4A,SPEG,MRPL37,MRVI1,CHST15,TOMM40L,FKTN,FDFT1,FGF11,FGF13,AMOTL2,IP6K2,SEMA6C,FLYWCH1,SORBS1,SPECC1,FAM49B,ARFGAP2,ZNF605,ERGIC3,DACH2,B3GAT1,DOT1L,PHYHIPL,GALNT15,GABRB3,BRPF3,TMEM8B,CPLX2,CYP46A1,ADAM28,GGT7,GLYR1,TNRC6A,GLUL,DCLK2,GNAS,ATF7,RAPGEF4,GRIA1,GRIK1,ADAMTS8,LINC00839,RNF165,LINC01551,MUM1,UBE2QL1,IGSF21,NEGR1,IGF1,TJAP1,IGSF1,SCRT2,ZNF678,NME9,SLC35G1,KCNA1,KCNJ4,KCNK2,KTN1,HECTD2,MAPT,KCTD6,SCAMP5,POC1B,AFDN,MOBP,PTOV1,MYO6,MYO9A,NEUROD2,NF1,NFIA,NFYA,NINJ2,NME4,VWA2,IGSF11,ZDHHC22,PAK3,PAX6,CDK18,PRTG,PDE4A,PDE4D,PDPK1,PFKFB3,ZDHHC8,NLE1,FTO,PLIN1,EPN1,HMGCLL1,PLXNB3,CDIP1,STRN3,PRRX1,MBOAT7,POLG,PPP1R1A,KANSL1,RASGEF1B,MAPK4,DCHS2,SAMD9,BCAS3,WBP1L,DEF8,UHRF1BP1,PTHLH,RAB3A,RAB3IL1,ACSS3,IQSEC3,RDX,CCDC82,MYH14,FBXW7,ACER3,AMER2,SEMA6D,SOX6,CASC3,FAM102A,FERMT1,KIF16B,ASAP3,SHMT2,FBXO11,FHOD3,ANKRD6,SLC1A3,EPN2,SLC6A11,SEPHS1,SLC8A1,SLC11A1,SLC12A4,SLCO1A2,SLIT1,CPEB4,SLN,SMARCC2,SORCS3,CDK5RAP2,RCOR3,INAVA,SNRPN,FAM219A,MYT1L,SOX10,ZSWIM8,MYCBP2,KDM4C,SPTB,IQSEC2,SRPK2,LRRC4,SSPO,MAPK8IP3,CEP68,STX1A,NECAB1,VAMP1,RHBDL3,PLCB1,SYN1,ANKRD28,ROBO3,TBCEL,FBXW11,WSCD1,WDR7,AZIN2,RALYL,PCDHB6,NSD1,AKNA,ARHGEF12,PCDHA5,FRYL,CYB561A3,GPR161,ZMAT3,AKTIP,THRA,TIAM1,MTMR14,BHLHB9,ZFP91,NR2E1,RBFOX2,ZNF346,STXBP4,TRPS1,FNDC5,TSC1,PRR18,GORASP1,MGAT5B,MEAF6,VLDLR,TSPAN11,NSD2,TRIM9,ZNF70,GPR158-AS1,ZNF213,MEIS3,PMEPA1,PRDM2,PRTFDC1,DNALI1,LRP8,CSDE1,PRDM8,PCDH15,GAL3ST3,NAV2,MPPE1,MVB12B,PDSS2,CASC15,CERS6,MSRB3,TTC7A,CBLN2,JPH3" MicroRNA hsa-miR-186:PITA hsa-miR-186:PITA_TOP PITA 1.51E-120 8.49E-117 1.41E-119 1.30E-118 246 809 "CLK4,NDRG3,ADAR,KLHL32,ADD1,PWWP2A,ZNF608,INTS2,OSBPL8,BCAR3,CDC42BPA,DPP10,LRCH2,ANK3,MAP4K3,CNTNAP1,USP37,ARHGAP5,RGS20,CADPS,BRINP2,ZBTB10,DDX3Y,NOL4,CDK5R1,NIPA1,BTRC,CALB1,CANX,VXN,SYT6,CAST,MAP7,MTMR7,TMEM257,C1orf52,LRBA,SEPT7,CDC42,CDH10,DLGAP2,ADGRG1,CHGB,SOCS6,SYNPR,CNOT8,FHL5,SLC4A7,ZNF385A,AKAP12,ATRNL1,CNTNAP2,RIMS2,KIAA0408,ZFYVE16,LONRF1,RIMS3,YTHDC1,ZC3H11A,SNAP91,G3BP2,GRIN3A,NR1D2,CDON,CPEB2,PDCD6IP,FRY,YAF2,FAM13A,MBNL2,TENM1,ELAVL2,PLEKHA1,TMEM35A,PAN3,EPHB1,SRRM1,ERBB4,EYA1,ACSL4,PTK2B,DLC1,SEC24B,MEX3B,AGAP2,SYNCRIP,SEMA4D,NBEA,KHDRBS3,CELF1,STAU2,ZNF512,STAG2,GABRA4,GABRB3,CAB39,BRPF3,TNRC6A,EML4,GRIA2,C1QL4,GRIA4,GRM5,IL1RAPL1,FICD,ZHX1,KLF12,BACH2,MIER3,HMGB1,NEGR1,AGFG1,ZIC5,INSM1,LRRTM3,KCNA1,KCNC2,KCND2,KCNK2,STXBP5,SMAD1,MAP2,MAP4,MBNL1,CHIC1,MITF,ERICH3,MXI1,MYT1,NASP,CNOT4,IGSF11,GPR137C,PCSK2,PDE3B,PDE4D,GPR85,PFKFB4,CDK14,SERPINE2,PIK3C2A,ZNF655,RETREG1,MAPKAP1,LRP12,EPB41L4B,NXPH1,PPP2R2C,PPP3CA,PPP3CC,PKN2,DIRAS2,RELN,PTPRO,FAM120C,PID1,USP47,SLC6A15,ZMAT4,GTDC1,FIGN,ZFHX4,HUNK,NCBP3,SALL1,SEMA6D,SATB1,SCN2A,SCN3A,SCN8A,FNIP1,SMPD3,RASA3,SCAF8,FERMT1,CPEB3,NTNG1,CHD9,FNDC3A,ABLIM3,SLC1A2,BTBD3,EPN2,TRIM67,SLC12A2,CPEB4,SNAP25,MBD5,FAM126B,MYT1L,ZCCHC24,SOX11,SP4,PEG10,ARHGAP26,CDK19,RBM26,NPAS3,LMO3,SRPK2,CLASP2,NECAB1,ARHGEF9,ANKRD12,CAMTA1,TAL1,ACSL6,TCF4,DMXL2,ZFP90,PSD3,NSD1,PUM2,SIRT1,HEY1,ZFP91,RBFOX2,TPM1,DOK6,TRPC1,TRPS1,TSN,FAM155A,UBE3A,AMOT,MEAF6,BEST1,WIPF1,ZIC3,ZNF711,SYNC,PMEPA1,CADM2,CSDE1,PRDM10,SNX27,KCNAB1,WNK3,SLC17A6,FZD3,PAK5,PHTF2,FXR1,SOCS4,SENP7,JPH3" MicroRNA hsa-miR-548f:PITA hsa-miR-548f:PITA_TOP PITA 1.59E-120 8.93E-117 1.48E-119 1.37E-118 249 830 "KCNH8,CSMD3,FMNL2,ADCY2,CCDC85A,USP31,NLGN4X,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,LRRC7,AMPH,CDC42BPA,ALS2,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,DDX3Y,SLC4A4,ATP2B1,N4BP2L1,ADGRB3,CDK5R1,SYNJ1,ARHGEF7,FUBP1,NIPA1,WASF1,CACNB4,CALB1,CALM1,PTBP2,CANX,RUNX1T1,SEPT7,CDH10,CLGN,NOG,SRSF11,SOCS6,LHX2,NRXN2,CLTC,FAM19A5,QKI,NIPBL,BAG4,ACBD5,CLOCK,CDC42BPB,CREM,CREB5,CRMP1,ATRNL1,ERC2,PLCXD3,CTNND2,ST18,HDAC4,LONRF1,MATR3,DGKB,TOMM20,MYEF2,ZC3H11A,DDX46,G3BP2,FAM107B,DMD,USP3,DSCAM,DYRK1A,HIPK3,RBM12,EFNB3,KMT5B,ABI2,EIF4G2,ELAVL2,STARD3NL,EIF1,EPB41L1,TAOK3,ATP8A1,FGF13,FGFR3,SUCO,FOXO3,FAM49B,DACH2,B3GAT1,STAG2,GABRB1,GABRB3,GABRG2,HBS1L,MSTN,AHDC1,MMADHC,GLS,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,PTPN5,SOX21,PSIP1,GYG1,BACH2,MIER3,HLF,NEGR1,SMAP1,BRINP3,LRRTM3,KIF2A,KIF5C,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,NFIA,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,CDK14,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,POU3F2,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,FAM120C,TTC13,RAB5B,PID1,CEP97,ARID4A,RBBP8,RADX,ZYG11B,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,ATXN1,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,WDTC1,SOX1,MYT1L,ZCCHC24,SOX11,SOX15,LMO3,SRPK2,TAB2,CLASP2,EPB41L3,SS18,ERBIN,ST5,RGL1,PLCB1,SYT4,ANKRD12,CAMTA1,CAMSAP2,WWC1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,RALYL,TMEM121,ZFPM2,TGFBR3,SLC44A1,DDHD1,TLR4,ERCC6L2,KCNE5,TUB,TUBB2A,RPRM,AMOT,FLRT2,WIPF1,NSD2,ZBTB14,ZNF711,ZFAND5,SMARCAD1,WNK1,CA10,PMEPA1,EMSY,CSDE1,STOX2,NAV3,SNX27,KCNAB1,PCBP4,WNK3,PDSS2,GOPC,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-33b*:mirSVR_lowEffct hsa-miR-33b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-120 9.86E-117 1.64E-119 1.51E-118 316 1345 "CPNE2,EMILIN3,SYS1,FAM43B,CSMD3,ADCY2,ADD2,ADORA1,KIAA1211,RNF150,PTCHD1,BEND6,NLGN4X,SLC24A4,GPR158,PCDH19,SYT13,AMPD2,PKP4,APBB1,APC,FAM131A,VAT1L,SHTN1,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,CAPRIN2,DDX3Y,ATP2A2,B3GALT2,LINC00847,DCAF5,BID,KSR1,SYNJ2,GYG2,RAB29,CDK5R2,CACNB4,SLC25A14,VXN,CERS5,SCARB1,CD38,SEPT7,LRRFIP1,LGI1,MAGI1,CHGA,ASIC3,CHN2,CASC2,DLGAP3,RAB33A,CLTA,FBXO7,TJP2,QKI,SRP14-AS1,RAB26,SUMF2,SLC35F1,C1QL2,GDA,SNCAIP,RGS6,FEZ2,FEZ1,GALNT9,VCAN,CTH,EDRF1,GIT2,SPATA2,YTHDC1,DGCR5,HEPH,ELMO1,CEP170,SACS,SV2B,SV2A,NTM,DPH1,DYRK1A,EDN1,ANKRD46,CNNM1,HEYL,FAM13A,PLXNC1,EIF5,ELN,EPHB1,VPS26C,RASL12,GMPR2,HSPA12B,FAM198B,ZNF585B,DLC1,FCGRT,ZSCAN30,TESK2,KIAA1109,FGF1,SPSB4,PCYOX1,SLC37A3,FOLH1,DPYSL4,SORBS1,ARFGAP2,ZNF605,ADGRA1,AP4B1,NRG3,GABRA2,GABRA3,GABRB3,CAB39,JPH4,GALR1,ERAP1,DISC1,LRRC37A6P,GATM,NEU3,TUBA8,MSTN,HPGDS,TOX3,RAB40B,DIPK1C,STON1,GRIA1,GRID1,SERP2,GRIN1,NR3C1,LINC00839,GUCY1B1,IGSF21,PADI2,PTGDR2,MAN1B1,MSL1,DOCK7,IGSF1,IL6R,IL6ST,JAK1,KCNA1,KCNJ11,KCNK1,KCNK2,KIF5A,KIT,KTN1,FGFBP3,GPR155,SYT9,LDLRAD3,LRP1B,SCAMP5,SAMD5,ADAM22,MSR1,MTTP,MTR,MYO5A,HNRNPM,NAP1L1,ZC3H12B,CCDC13,DNHD1,SLC11A2,GPR137C,PBX1,PDE1B,PDYN,PFKFB4,HERC2P3,XRN1,NLE1,ST8SIA5,SLC25A23,PCDH18,SCHIP1,MAGEL2,SLC36A4,FAT3,FSD1,PPP2R5E,PPP3CB,HYDIN,SIDT1,GON4L,MDGA2,CNTLN,MTMR10,ELOVL2,OCIAD1,PTPRE,TMEM255A,FAM184A,ZNF493,BSDC1,TRIM68,GTDC1,SLC25A36,ALG9,ARMC5,CCDC25,ZC3H14,ATP8B4,SGSM1,EMID1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,SEMA6D,DRAXIN,ATXN2,ATXN7,HOGA1,SLC30A10,PEAR1,CASC3,MRAS,SUPT20H,ASAP3,SHMT2,MAGI3,CHD9,ANKRD6,CLSTN1,SLC1A7,BTBD3,KANSL3,LRRC55,YPEL4,SCMH1,ELMO2,BTBD7,NAXD,SMARCD3,RCOR3,SNCA,KIF13A,SNRPN,TMCC1,UNC80,TNIK,NMNAT2,EMC1,C11orf87,SRPK2,STOX1,MAPK8IP3,NEK4,ADHFE1,MLC1,VWA3A,SIN3B,TCF7,TRIM2,AZIN2,PHF24,FRYL,DICER1,DICER1-AS1,ZFPM2,CRB1,AP4E1,GALNT17,LRRC8A,KCTD2,TP53BP2,STXBP4,SGK3,HEPACAM,CADM1,RPL7L1,UBTF,UCHL1,UGT8,SLAIN1,CCDC14,GUSBP1,XPO1,ZNF711,ZNF24,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,SLC30A4,PRDM2,CSDE1,SNX27,EPM2A,RGS7BP,DOCK8,RTN4,NUP214,TRAM2-AS1,RNF170,DPF3,LAS1L,SENP7" MicroRNA hsa-miR-888*:mirSVR_lowEffct hsa-miR-888*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.89E-120 1.06E-116 1.75E-119 1.62E-118 345 1594 "RALGAPA1,SYS1,ADAR,KLHL32,GALNT13,ADD1,CDC7,ERMN,INTS2,BCAR3,ABCD2,ARHGAP20,PCDH10,DOC2A,ZFAT,LRCH2,SUGT1P4-STRA6LP-CCDC180,PARG,APAF1,EPB41L5,GPAM,ALS2,NT5C3B,SHROOM2,AQP4,MADD,SPTBN4,RGS20,ASCL1,MARK4,CAPRIN2,ASPH,NCOA1,DDX3Y,BLM,BMPR1B,DST,ST3GAL5,SYNJ2,NIPA1,OSGIN2,MMD2,DDR1,THSD7A,HAP1,MTMR7,CBFA2T2,LRBA,DCLK1,CHGB,KMT2C,CLCN4,CLTC,FBXO7,ABCG2,QKI,CNR1,CNTFR,AKAP7,ARMC8,SLC4A7,CLOCK,ENTPD4,ANKRD44,CHD5,NCAN,SOCS5,PLXNA4,CMTM5,DCAF4,NOS1AP,MYADM,ARHGAP32,KATNAL2,TOX,KIAA0513,ZNF337,MATR3,YTHDC1,ELMSAN1,DNAJC6,POM121,SV2B,NTM,AK5,KBTBD11,DLX1,RAB39B,DMD,OLIG1,NYAP1,SLC12A6,PDCD6IP,EDN3,HIPK3,TMTC1,APH1A,ABI2,C8orf37,EPHA5,EPHB1,ERBB2,EFS,MRPL10,NSRP1,FAM198B,TAOK3,EFEMP1,CEP78,FCGR3A,ZSCAN30,TESK2,KAT8,FER,AMOTL2,AGAP2,ANKFY1,SORBS1,SMC2,UFM1,PDLIM5,STAMBP,ARFGAP2,CAMKK2,ATP2C1,CELF1,DACH2,ZMAT1,GABRA2,CHL1,FAM120B,RAPGEF6,INPP5K,GATM,ALDH1L1,GCNT2,TUBGCP4,MMADHC,RNPS1,GLYR1,TOX3,HTATSF1,LOXL3,RAPGEF4,ATP2B1-AS1,GRB10,GRIA2,DIDO1,GRID1,NR3C1,GRM8,FAM19A2,MFSD2A,GUCY1A2,ADAMTS6,WIF1,HPS5,PTGDR2,BACH2,ZDHHC15,FAM95B1,ZNF546,C5orf24,RBPJ,KNDC1,LIX1,ITGAV,KCNJ16,KCNK3,KTN1,LIFR,LIMS1,GPR155,MAP4,MAP6,MARK1,MBD1,MBP,MDM4,MEIS1,KITLG,SCAMP5,MMP16,JAKMIP3,NAP1L3,NELL1,NELL2,ALDH1L2,DDR2,NUCB1,GPR88,P2RX7,ZNF827,PBX1,PDE4D,PDE1B,PDGFRA,ENPP2,PDPK1,SLC10A4,PFKFB2,PIK3C2A,PIK3R1,ZNF655,XRN1,PLP1,TRHDE,MAPKAP1,CDIP1,SCHIP1,SDK2,DRAM2,PPM1B,PPP2R5E,PRKAB2,RASGEF1B,MAPK10,DCHS2,WBP1L,SNRK,WDR25,UHRF1BP1,MTMR10,PTPRE,PEX2,ZSCAN2,TUG1,QDPR,USP47,ZNF793,RBBP6,REV3L,FIGN,RFX3,PBRM1,RNASEL,EXD2,ROBO1,ROBO2,PCMTD2,NEK11,UEVLD,FBXW7,ZNF671,MCMBP,ACER3,ATXN7,SCN3A,SCP2,GALNT10,MRAS,NTNG1,SHC4,AMBRA1,FHOD3,ST3GAL3,ZNF365,FAM81A,DHX30,KDM4D,SLC8A1,RAB3GAP1,SLC8A3,SLC11A1,KBTBD4,SLN,SMARCA4,SNCA,MBD5,KIF13A,SNRPN,MYT1L,SOX11,DOK5,KDM4C,TEX2,CDK19,SRPK2,TROVE2,MESP1,SAMSN1,SSPO,ST5,MPRIP,SEPT8,CEP68,ADHFE1,KANK1,GSE1,KLHL7,ZC3H4,FNDC9,SYN2,TAL1,TRIM2,TCF12,SYNE1,NAT16,RALYL,PUM2,TNS2,FRYL,SIK3,ATP13A2,TF,FAM200B,DICER1,DICER1-AS1,AP4E1,HEY1,KAT6B,PIK3R5,NPL,ZMYND8,FNDC5,ANO5,TSC2,CLHC1,LINC00689,PITPNB,FLRT2,FAM181B,TBC1D15,NSD2,ZNF708,MICU3,ZNF28,TRIM9,AGMO,MKRN3,LYPD6,REEP1,POLR3H,ANKS1B,FTSJ1,EMSY,GDPD5,STOX2,URM1,FIP1L1,MPPE1,GOPC,ST7,ADAMTSL3,AP3B2" MicroRNA hsa-let-7c*:mirSVR_lowEffct hsa-let-7c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-120 1.62E-116 2.68E-119 2.46E-118 341 1561 "NCKAP5,KLHL32,DSCAML1,SLITRK1,PWWP2A,KIDINS220,BEND6,INTS2,CASKIN1,KCTD16,TXNDC16,AK2,BCAR3,MARCH4,GPRASP2,PITPNM2,BIN1,ANXA7,CNTNAP1,APAF1,EPB41L5,UPRT,TNRC6C,LGR5,SHROOM2,CDC14B,PPP4R4,IGDCC4,CASK,RASL11B,TMEM108,SLC4A4,ATP2B1,ATP2B2,SLC2A11,N4BP2L1,DCAF5,ST3GAL5,FUBP1,SCAPER,MTMR3,SGCE,THSD7A,CAST,CCNH,CBFA2T2,SEPT7,REPS2,CDC27,CDH18,NUMBL,SRSF11,ASIC3,CASC2,JAM2,NDST3,RAB28,NRXN3,NRXN1,CLTC,NIPBL,TMEM155,CNN3,CNTN1,ABI3BP,TOGARAM2,MYRIP,CNRIP1,HINFP,ANKRD44,CSF2RA,SEC24C,SLITRK5,PPP1R16B,PLCXD3,RUBCN,FAM131B,ZFYVE16,MAML1,DGKB,TMEM170A,SIRPA,SPATA2,ELMSAN1,C8orf34,BLOC1S6,RABGAP1L,WDR20,DLX1,DRP2,GNE,DTNA,EDN1,EDN3,EDNRA,PHC2,RASGRP1,SEMA3D,KLHL5,GOLGA7,STARD3NL,USPL1,EPHA5,GMPR2,FAM198B,AMZ2,DLC1,GORAB,SEC24B,KIAA1109,FGF13,CAMSAP1,SUCO,SCARA3,FOXO3,ATP13A4,SGIP1,EFCAB2,HVCN1,ARFGAP2,KHDRBS3,CELF1,DACH2,GPR153,ST6GALNAC3,CSPG5,MPP6,GABRA2,GABRB1,GABRB3,ZMYND11,GALC,ZNF559,C15orf41,WASF3,MYOZ2,ALDH1L1,MSTN,CYP46A1,KIRREL3,LYVE1,GLDC,GLI2,RAB30,PCDH11X,ZNF638,DCLK2,PRUNE2,PRLHR,GPR12,GPR22,NUDT21,PCLO,GRB10,NR3C1,GRM7,KIF3A,RNF165,WIF1,IRAK3,MAEL,PADI2,ARHGAP19,BACH2,HNF4G,LRRC75A,CELF5,SMAP1,LINC00667,ZNF546,KNDC1,INPP5B,ITPKA,KCND2,KCNJ3,KCNJ10,KCNN2,KIF5A,KLRC2,IPO5,STXBP5,CYP27C1,KTN1,LIFR,NCOA7,GPR155,MBD1,MOV10,CD200,MSI1,MSR1,CTNNA3,MTR,MDGA1,ZNF862,NFIA,ALDH1L2,CNOT4,LRIT2,NUCB2,CNTN3,PBX1,PCDH9,PDE1A,PDE4D,GPR85,PFKFB2,SEMA5B,ZNF655,CCSER2,KCTD15,PDZRN4,STRN3,SCHIP1,ING3,CRLS1,PPP2R5C,PPP3CA,PRKAB2,PROX1,MASP1,SAMD9,PLPPR1,FAM120C,PTX3,FAT4,RASGRF2,FEZF2,ZYG11B,RIC8B,NUDT11,LGI2,RERGL,C12orf49,CARF,KIRREL1,RORB,RPE,RPE65,NEK11,BAALC,GLDN,PRR5L,LRRK2,ABCA11P,WLS,RTN1,TRAPPC13,DGLUCY,FOXRED2,CSRNP3,SEC14L1,SOX6,FOXRED1,TRA2B,KIF16B,FBXO11,ABLIM3,SIRT2,CDK5RAP3,ATF7IP,SLCO1A2,CPEB4,SMARCD3,LIMCH1,KIF13A,SNRPN,UNC80,KDM4B,SON,TNIK,BDP1,NMNAT2,ZNF423,KIF1B,ZBTB43,RBM26,TAB2,PBLD,ITPRID2,STOX1,ZC4H2,LARP4,SS18,SSPO,NXT2,KANK1,JMJD6,VPS13A,ANKRD28,ANKRD12,TBCEL,FBXW11,TMEM136,VWA3A,SATB2,TCF7L2,ZEB1,SYNE1,SLC19A3,PSD3,PCDHB3,GPRIN3,HIF3A,CRB1,TJP1,BEX4,KCTD2,TPD52,PDSS1,ZMYND8,RUSC1,ANO5,SGK3,GORASP1,FLRT2,VLDLR,XPO1,ZBTB14,ZIC3,ZNF24,NDRG4,LYPD6,TCEAL7,CELF4,SPIRE1,SYNC,WNK1,CADM2,PRDM2,LRP8,EVI5,SCG2,PCDH15,SNX27,KCNAB1,SLC17A6,PDSS2,MSRB3,GAN,ZNF30" MicroRNA hsa-miR-573:mirSVR_highEffct hsa-miR-573:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.74E-120 3.22E-116 5.32E-119 4.90E-118 307 1276 "CLK4,CSMD3,CCDC85A,ADD1,ADD2,CDC7,PWWP2A,ADORA3,BEND6,SLC44A5,SPARCL1,FAM135A,AMPH,DPP10,ANK2,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,DDO,AQP4,ARHGAP5,CDK13,MARCH3,ASPH,NCOA1,STX16,B3GALT2,BACH1,ADGRB2,DST,SYNJ2,MTMR2,JAZF1,IL33,CACNA1B,CACNB2,KALRN,CAMK2D,NFS1,LDB2,METTL6,P2RX6,CD86,SCARB1,CDH2,CDH10,ZMYM4,LRRFIP1,L3MBTL4,CACNA2D2,CHGB,CHN1,CHN2,KMT2C,RAB33A,NRXN3,CLU,CLTC,AKAP6,LETMD1,SLC4A8,BAG4,GDA,MICAL2,VCAN,NCAN,PDE4DIP,PHF14,CTNND1,NRSN1,ST18,CYBB,TOX,LIN54,DCC,ZEB2,MYEF2,KIAA0319,CEP170,DDX46,RHOBTB1,SV2B,USP3,DMTF1,DNAJB6,FAM135B,EDNRB,SYT15,RBM12,FAM13A,PHF20L1,EGFR,ABI2,RASA4,AASS,GOLGA7,SORBS3,KCNMB2,RTN3,RRAGB,SIRPB1,CLVS1,SH3YL1,EFEMP1,ZNF589,FGF11,FGF14,FLT1,NELFCD,AKAP3,TMEM107,SMC2,HVCN1,ST6GALNAC3,NSG1,STAU2,PHYHIPL,DKK3,ZNF44,CHL1,GABRG2,TRAF3IP2,FAM184B,FAM120B,GALC,B4GALNT1,ARPP21,SULT1C4,GFRA1,PCDH17,GHR,COPS8,LOXL3,GPD2,GPM6B,GPR22,GRIA4,GRIK2,SERP2,GRM5,GRM7,LINC01551,GUCY1A1,GYG1,IRAK3,MAEL,DDX19B,ELOVL5,HMGB1,C9orf129,HSPA1L,SMAP1,IGSF1,KCNC1,KCNN2,KLRC2,LAMP2,LMO2,LOC100128239,MAP4,MATN2,MBNL1,SYT9,EFHB,MEIS2,XRRA1,MOV10,SESN3,MSR1,MXI1,ZNF862,NAP1L3,NASP,NELL1,NEK1,NF1,NOVA1,HCN1,NTRK2,NUCB2,NUMA1,PCDH9,PCSK5,PCSK2,PDE3B,A2ML1,SNX10,PRIMPOL,TRHDE,EPB41L4B,CRLS1,PTPA,PKN2,PRKCZ,GRAMD1C,PROX1,VPS13C,DEF8,PTHLH,TMEM260,OCIAD1,PTPRD,PTPRE,PTPRO,FAM120C,ZSCAN2,PID1,CEP97,SLC25A48,OXR1,RASGRF2,RBBP6,RADX,SLC6A15,DPF2,ERI2,GTDC1,RGR,SEC61A2,EXD2,EPHA10,ATP8B4,ABCA11P,WLS,ZNF331,AP1AR,SEMA6D,ATXN2,SCN2A,LRRTM4,SCP2,COPZ1,ITSN1,SH3GL2,SH3GL3,CHD9,SLITRK3,CNKSR2,SYBU,NLGN1,SLC1A3,PREX2,BTBD3,RUFY2,ZNF430,SEPHS1,BTBD7,CPEB4,SMARCE1,SNAP25,SNRPN,UNC80,SOX5,SP4,NPAS3,PBLD,EPB41L3,ERBIN,DIP2A,ADHFE1,AJAP1,SYT1,TAC1,MCF2L,ANO4,EHBP1,ACSL6,SATB2,TRIM2,SYNE1,PCDHB4,GPRIN3,FAM200B,ITGB3BP,TGFBR3,THBS4,TLL2,ERCC6L2,HEY2,KAT6B,TNR,RUNDC3B,TRPC1,RFTN2,ZKSCAN5,XPO1,XRCC4,ZBTB14,KCNT2,ZNF74,MKRN3,ZNF184,ANKS1B,TFIP11,CA10,MFF,LRP8,TMEM178A,PCDH15,CAB39L,WNK3,FAM13C,FBXO36,JMJD1C,ZNF248,RNF146,SENP7" MicroRNA hsa-miR-363:mirSVR_highEffct hsa-miR-363:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.16E-120 4.02E-116 6.62E-119 6.10E-118 270 987 "SYN3,RBM10,NCKAP5,CSMD2,CSMD3,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,HECW2,TAOK1,C1QTNF3,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,MIER1,ASPH,DDX3Y,ATP2A2,RNF182,MTMR9,B3GALT2,DOCK11,ADAM23,ADGRB3,MPDZ,HCN2,CDK5R1,SYNJ1,CACNA1I,OSGIN2,KALRN,CAMK2A,MAP7,MTMR7,AIFM1,CDC27,CDH10,CFL2,SOCS6,CHM,NRXN3,HECTD1,NIPBL,TMEM155,CNRIP1,HS3ST5,FAM171B,CRHBP,SLC32A1,ANKRD44,ATRNL1,SOCS5,SLITRK5,ERC2,APPL1,CTH,EDRF1,ECE2,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,G3BP2,CDON,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,PHF20L1,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,TMEM74,KIAA1109,POLK,SUCO,ATP13A4,SLC37A3,TACC2,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,GABRA1,ARPP21,IQGAP2,GAP43,GHR,SPIN1,GLYR1,PCDH11X,FERMT2,CNDP1,GPD2,GPM6A,GPR12,TPPP,GRIA1,DIDO1,RFFL,GRM1,GRM3,GRM7,HAS2,MIER3,ELOVL5,SCRG1,HNMT,MSL1,RBPJ,BRINP3,SLC6A17,ITGAV,C2CD4C,KCNK1,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,MN1,MOBP,ERICH3,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,DNHD1,SMIM11A,OLR1,CLDN11,P2RX7,GPR137C,PDE1A,PIK3R1,CCSER2,SNX10,ZFYVE21,PLCL1,JAKMIP1,PDZRN4,TRHDE,STRN3,ING3,PPP3CB,CEP41,RAB39A,GON4L,ZSCAN32,PTPRD,PTPRO,PTPRZ1,PEX5,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RPE65,RPL15,FBXW7,MCMBP,LGR4,ABCA11P,AP1AR,SATB1,SCN3A,FAM19A1,FNIP1,SUPT20H,CPEB3,MYO18A,CNKSR2,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,SNRPN,PALLD,MYO16,UNC80,SON,PDZD2,MYCBP2,TEX2,KIF1B,NPAS3,PBLD,ITPRID2,SS18,ELOVL4,RGL1,AJAP1,FGD4,SYNE2,SYN2,SYPL1,SYT1,SYT4,TAC1,CAMTA1,ANO4,DOCK9,AHCYL2,SIK3,HHIP,GALNT17,TMPO,KCTD2,TPM4,SYNPO2,TRIO,SGK3,CADM1,UGT8,VLDLR,CLDND1,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,FMN2,ZNF142,MFF,CADM2,LRP8,EVI5,RNF103,ADAMTS9,KCNAB1,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,NETO2,SLC4A10" MicroRNA hsa-miR-302d:mirSVR_highEffct hsa-miR-302d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.69E-120 4.32E-116 7.10E-119 6.54E-118 331 1479 "KIAA1211,PTCHD1,MTUS1,GPR158,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,ASPH,STX16,B3GALT2,DPY19L3,ATP6V1G2,BACH1,MPDZ,DCAF5,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,SGCE,CA12,CACNA1E,CALB2,SYT6,AIFM1,MAGI1,CFL2,CHN2,CNOT8,TAOK2,IGFBP7-AS1,ABCG2,C4orf33,AKAP5,ACBD5,IGDCC3,CNRIP1,ZNF385A,CPS1,CRHBP,ANKRD44,SNCAIP,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,TOX,KIAA0586,DGKG,DCC,ZNF804A,MYEF2,HP1BP3,MAGI2,BLOC1S6,ZC3H11A,G3BP2,RABGAP1L,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,GOLT1B,E2F5,E2F6,EDN3,EDNRB,ANKRD46,HIPK3,YAF2,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,VPS26C,DNAJC27,WAC,CORO2B,MED12L,POLK,SUCO,NELFCD,EFCAB2,USP16,MSANTD4,ZNF512,FYB1,MEGF11,CAB39,ZMYND11,ARPP21,MYOZ2,IGSF5,TUBGCP4,ADAM28,GGTA1P,MALT1,COPS8,GLDC,TOX3,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPM6A,GPR12,GPR34,PCLO,ATP2B1-AS1,GRIA1,GRM5,TMEM25,UBE2QL1,HPS5,ARHGAP36,HMGB1,ZDHHC15,HSP90AA1,SMAP1,MSL1,IDH3B,JAK1,OLFM3,KCNMA1,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SYT9,MDM4,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPA1,OPHN1,PCDH9,PCSK2,PDCD2,BEST3,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,HMGCLL1,PRIMPOL,TRHDE,PRRX1,SPATA6,DRAM2,PPP2R5C,PPP3CB,RASGEF1B,PRKACB,PKN2,GRAMD1C,MASP1,SNRK,QRICH1,CNTLN,PTHLH,PXK,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,CCDC102B,RPE,TMEM100,MCMBP,LGR4,RPS20,RTN1,AMER2,SCN2A,SCN3A,IL17RB,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,SOX2,TNIK,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,LRRC4,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,UNC5D,ADGRL3,AGTPBP1,TBCEL,TCEA1,ZFP90,CUX2,ZEB1,SZT2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,NACC2,NR2E1,TNS1,TPD52L2,C9orf85,WBP2,RGMB,PRMT8,TRPC1,PPIL6,FAM181B,ZNF709,VLDLR,PCDH20,TRIM9,FMN2,LYPD6,LAMP5,SYNC,CADM2,PRDM2,PRTFDC1,RGMA,PRDM8,PRDM10,RNF103,NELFE,PLSCR4,FAM13C,MRPL47,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-4260:mirSVR_lowEffct hsa-miR-4260:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-119 5.68E-116 9.32E-119 8.58E-118 327 1446 "CPNE2,ABR,ASIC1,ABHD6,CSMD2,ARID1A,CSMD3,TMEM132B,DSCAML1,SLITRK1,GALNT13,ADD2,GRAMD1B,DPY19L2P4,AP1B1,HECW2,CASKIN1,KCTD16,KIAA1324,CC2D2A,C1QTNF3,MARCH4,LTBP4,AMH,AMPH,OGT,LRCH2,SUGT1P4-STRA6LP-CCDC180,DGKZ,GPAM,ALS2,AMER3,BCAS1,AQP6,PRX,MADD,SPTBN4,LINC00173,PDE8B,MARK4,CHID1,ATP6V1G2,TTLL9,ADAM15,BCHE,DCAF5,CFLAR,JAZF1,GYG2,NIPA1,GPC2,KALRN,NGB,SLC25A14,SPAG9,CBLN1,CBR1,CBS,CD38,NEURL1,ASIC3,COG1,NMT2,QKI,HECTD1,COL9A1,LETMD1,SLC4A8,SEC31B,AKAP12,CRYBB1,TENM4,MICAL2,PDE4DIP,PLXNA4,PPP1R16B,CTNND2,RIMS2,CX3CR1,ECE2,ARHGAP32,GAPVD1,SNPH,ARHGAP24,PHYHIP,IP6K1,AIF1L,ARMCX4,PITPNC1,ELMSAN1,DNAJC6,CNIH3,SNAP91,SV2A,SRGAP3,G3BP2,TMCC2,DLG2,EXOG,RAB39B,HS3ST2,RPS6KL1,DNM2,ECM2,DNM1L,AASDH,ST8SIA3,EDNRA,TMTC1,TMEM132E,AASS,CALCRL,SEZ6,GPHN,FCGRT,FKTN,PRMT5,FGF11,SPSB4,FGFR1,BAIAP2,MAD2L2,FGR,SUCO,SCARA3,EFCAB2,CGREF1,TPPP3,NRG3,ZNF512,FYB1,DKK3,GAB1,GABRA3,GAD2,BRPF3,FAM120B,ZNF274,GCK,TUBA8,GFRA2,TTBK1,GLS,TNRC6A,GNAS,ADGRA3,STON1,CECR2,PCLO,STMN2,GRB10,GRID1,SPACA9,ADAMTS13,RNF165,AP4S1,LINC01102,SMAP1,ZNF546,IGF1,IGSF1,IL6ST,ZNF678,KCNMA1,KIF5A,KLRC2,LRRC4B,SFXN5,LIMS1,HECTD2,ARHGAP12,ZFYVE27,MAOB,MAT2A,CHIC1,MEIS2,MOG,PTOV1,MDGA1,MYO7A,RTL5,NAP1L1,NBL1,NCAM1,NF1,SLCO1C1,NOVA1,NPTX2,NRGN,OGG1,DPY19L2P2,PENK,PFKFB3,PFKFB4,ZDHHC8,FAM216A,FXYD1,SLC25A23,HMGCLL1,PURG,C11orf49,PMP22,RETREG2,POLR2F,CRLS1,PPP3CB,PRKCG,PKN2,DIRAS2,CNNM2,BCAS3,GDPD2,CNTLN,TMEM260,ZSCAN2,RAD52,ZNF793,SLC25A41,RAP1GAP,DBX2,GAL3ST4,SLC6A15,ZMAT4,GTDC1,UBR7,RGS12,CCDC82,SETD5,TMLHE,ALG9,PRR5L,ACER3,TCP11L1,KCNIP3,KCNIP2,SEMA6D,SBF1,TNFRSF19,ASIC4,CASC3,SCAF8,ITSN1,SH3GL3,MAGI3,FHOD3,R3HDM2,ABLIM3,EPN2,PKNOX2,SLC8A2,SEPHS1,SLC9A5,SLC11A1,KBTBD4,NAXD,SLN,SMARCC2,MBD5,CABCOCO1,SNRPN,TMCC1,UNC80,RBM34,PDZD2,WDTC1,ZCCHC24,ZHX3,ZSWIM8,KIF1B,COLGALT2,SMOC1,NKAIN2,ELOVL4,SEPT8,MLC1,FGD4,ZC3H4,VAMP1,VPS13A,SLC37A2,UNC5D,FBXW11,MGRN1,TCF12,TMEM151B,ARHGEF12,ARHGAP9,ATP13A2,CRB1,SPX,ITGB3BP,LEFTY2,ZFP91,ERCC6L2,DAAM2,TPM2,ELP5,DCBLD1,TSN,HEPACAM,SLC35A4,UBE3A,FLRT2,PLEKHH2,VSNL1,WIPF1,XRCC4,LGI4,ZIC1,ZNF32,ATP6V0E2,MKRN3,LYPD6,PCBP1-AS1,ZNF213,MEIS3,UPF3A,SLC30A3,PRDM2,GDPD5,PRDM8,PCDH15,KCNAB1,AMN1,HNRNPA3,GJC2,NETO1" MicroRNA hsa-miR-509-3p:mirSVR_lowEffct hsa-miR-509-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.34E-119 7.53E-116 1.24E-118 1.14E-117 290 1143 "SERPINA3,EMILIN3,ARID1A,FMNL2,GALNT13,ADD2,AXIN2,SLC12A5,SLC44A5,TBC1D14,HFM1,TAOK1,CEP126,DPP10,LRCH2,ANK3,GAS7,LGR5,ZFYVE28,ARNTL,ASCL1,CAPRIN2,DACT3,DDX3Y,ATP1A3,SLC4A4,ATP2B3,ZNF583,RGS9,CFLAR,KSR1,MTMR3,CACNB4,KALRN,CAST,MAP7,KRIT1,METTL6,NEURL1,DCLK1,LGI1,MAGI1,TIGD7,CCPG1,NOG,SRSF11,ASIC3,CHN1,NDST3,IGFBP7-AS1,CLU,NMT2,ARHGEF6,CABP1,COL4A5,CP,SLC35F1,RBM39,HAPLN1,PDE4DIP,CST3,DZIP3,CTNND1,ST18,SEC14L5,FGFR1OP2,SNPH,MATR3,DGKG,DNAL1,DCC,PITPNC1,ELMSAN1,FBXL5,SNAP91,SGSM2,GRIN3A,NR1D2,DNM2,DOCK2,DMTF1,ATN1,DTNA,ST8SIA3,SGK2,TMTC1,YAF2,EGFR,MBNL2,ABI2,COPS4,ELAVL4,EN2,OLIG2,GPHN,WAC,CEP78,PRMT5,ZNF589,FECH,IP6K2,FLT1,SLC37A3,EFCAB2,SORBS1,STAU2,GAB1,GALNT15,ATP8A2,LRRC37A6P,CYP46A1,PPARGC1A,RAB30,PCDH11X,GNG4,STMN2,GRIA1,GRIA2,GRIA4,RFFL,PRDM5,GRM8,FAM19A2,GUCY1A2,HAS2,PADI2,FRMD3,LINC01102,GABARAPL2,ZDHHC15,NEGR1,SOWAHA,RBPJ,KIAA1755,SCIN,INSM1,ITGAV,KCNC1,KCNJ10,KLHL23,KIF5C,STMN1,LMO2,SYTL4,ASPRV1,AQP11,MBNL1,MDM4,MIA2,KITLG,AFF1,XRRA1,MOBP,ADAM22,MT3,SCG3,RSPO2,MYO7A,ZNF862,NAP1L1,NCAM1,NEUROD2,NF1,NOVA1,DNHD1,GPR88,OLR1,GLIPR1L2,DPY19L2P2,PCDH8,PCSK1,NLGN3,A2ML1,SNX10,FAM216A,TRHDE,PRRX1,RETREG2,MINDY2,HYDIN,UHRF1BP1,BDNF-AS,PTPRD,PTPRH,FAM120C,NKAIN1,TTC13,USP47,RAP1GDS1,VEPH1,MSANTD2,RDX,RFX5,UBR7,CCDC82,SPIN3,SGSM1,STK32B,LRRK2,ATAT1,KCNIP1,RXRA,ATXN7,SCP2,IL17RB,COPZ1,KIF21A,PPP1R9A,KIF16B,DOCK10,MAGI3,CHD9,FBXO11,ST6GAL1,CNKSR2,ZNF365,PPP4R3A,PKNOX2,BTBD7,SLC22A4,ANKRD36,LIMCH1,MBD5,UNC80,DOP1A,PDZD2,SOX2,DOK5,ZNF423,DBNDD2,TSPYL2,RBM26,LARP4,NKAIN2,SS18,MAPK8IP3,SEPT8,KLHL7,NECAB1,SYNE2,NUDT10,ADAMTS17,ARC,SYPL1,SLC37A2,DDHD2,ADGRL3,SMG6,VWA3A,TCEA1,CUX2,ZEB1,OBSL1,NSD1,PUM2,DICER1-AS1,CRB1,AKTIP,TMPO,DAAM2,CSMD1,KAT6B,TPM3,ELP5,TRIO,PDSS1,ANO5,AMOT,UGT8,VLDLR,GUSBP1,XPO1,ZIC1,ZNF24,FMN2,SLC26A10,TCEAL7,ANKS1B,EMSY,CADM2,PRDM2,RNF103,NAV3,FIP1L1,PARP11,GOPC,PAK5,PHTF2,SSPN,DPF3" MicroRNA hsa-miR-302a:mirSVR_highEffct hsa-miR-302a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.83E-119 1.03E-115 1.68E-118 1.55E-117 329 1466 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,GPR158,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,ASPH,STX16,B3GALT2,DPY19L3,ATP6V1G2,BACH1,MPDZ,DCAF5,BID,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CACNA1E,CALB2,SYT6,ZNF501,AIFM1,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,IGFBP7-AS1,ABCG2,C4orf33,IQCK,COL4A5,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,ANKRD44,SNCAIP,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,HDAC9,TOX,KIAA0586,DGKG,DCC,YTHDC1,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,RABGAP1L,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,GOLT1B,E2F5,E2F6,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,VPS26C,DNAJC27,WAC,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,ZNF512,MEGF11,CAB39,ZMYND11,ARPP21,IGSF5,TUBGCP4,MSTN,ADAM28,GGTA1P,MALT1,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,UBE2QL1,HPS5,C1orf94,HMGB1,ZDHHC15,HSP90AA1,SMAP1,MSL1,IDH3B,JAK1,OLFM3,KCNMA1,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPHN1,P2RX7,GPR137C,PCDH9,PCSK2,PDCD2,BEST3,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,HMGCLL1,PRIMPOL,TRHDE,PRRX1,SPATA6,EPB41L4B,DRAM2,PPP3CB,RASGEF1B,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,CNTLN,PTHLH,PXK,TMEM260,PTPRO,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,RNH1,ZNF532,CARF,RPE,TMEM100,MCMBP,LGR4,RPS20,RTN1,AMER2,SCN2A,SCN3A,IL17RB,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,SOX2,TNIK,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,RGL1,STXBP1,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,UNC5D,ADGRL3,TBCEL,TCEA1,ZFP90,CUX2,TCF7L2,ZEB1,SZT2,PCDHB3,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,NACC2,NR2E1,TNS1,RGMB,PRMT8,TRPC1,PPIL6,FAM181B,ZNF709,VLDLR,XPO1,PCDH20,TRIM9,FMN2,LYPD6,LAMP5,SYNC,WNK1,CADM2,PRDM2,PRTFDC1,RGMA,PRDM8,PRDM10,RNF103,PCDH15,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-219-1-3p:mirSVR_lowEffct hsa-miR-219-1-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.20E-119 1.23E-115 2.02E-118 1.86E-117 354 1687 "RALGAPA1,TTYH1,ABR,CLK4,AS3MT,SYS1,ACTN2,CSMD2,ARID1A,KLRC4,GALNT13,ADD1,PWWP2A,KLHL13,WDR35,CC2D2A,ALCAM,PCDH10,BBOX1,FAM135A,AMPD3,AMPH,ANK3,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,LGR5,MADD,IGDCC4,ARHGAP5,ARHGDIA,LINC00173,CHID1,SLC4A4,ATP2A2,ATP2B2,N4BP2L1,DPY19L3,ATP6V0A1,KIF1A,RGS11,SCAPER,OSGIN2,CACNA1A,CALB1,PTBP2,VXN,HIP1R,MAP7,CCNH,DGKI,LRBA,CDH2,CDH8,CASC2,NRXN3,IGFBP7-AS1,KIAA1549L,CLTC,TJP2,QKI,MAP4K4,CNN3,CNR1,PCYT1B,ARMC8,LETMD1,CNRIP1,CRMP1,GDA,SNCAIP,CSF1R,ATRNL1,PDE4DIP,PHACTR3,CST3,ERC2,PLCXD3,RUBCN,SEC14L5,NOS1AP,TM9SF4,TBC1D5,TMEM170A,BRINP1,DNAL1,DCC,ARMCX2,CEP170,SV2B,AK5,RABGAP1L,SEC16A,DLX1,GRIN3A,DMD,HS3ST2,RCAN1,ECM2,TOM1,DNAJB6,E2F6,SNX29,FAM135B,TMTC1,OPTN,YAF2,CELSR3,KMT5B,RASA4,MRNIP,TMEM35A,CALCRL,TUBD1,LRRC23,EPHA5,EPHB1,EPS8,SPEG,APC2,RTN3,ADGRV1,TBC1D16,ZNF589,FER,GTF2IRD2,ATP13A4,C2orf88,PDLIM5,TRIM16,CELF1,DACH2,CSPG5,STAU2,DKK3,CHL1,ARPP21,NCKAP1,SIGLEC8,MTHFD2,KIAA1841,ALDH1L1,ZNF276,GLI2,MSL3,GNAO1,FERMT2,GOLGB1,GPD2,GPM6A,TDRKH,GRIA2,GRIA4,NR3C1,GRM2,RNF165,ZBTB49,RNFT2,PADI2,FRMD3,HMGB1,LRRC25,USP54,ZNF678,INSM1,LRRTM3,NME9,KCNH1,KCNJ10,KLC1,STXBP5,LMO2,FGFBP3,ASPRV1,SMAD1,MAOB,MAP4,MBP,ADAM11,TM6SF1,MDM4,LRP1B,AFF1,MRPL42,ADAM22,PTOV1,NRBP2,N6AMT1,TAGLN3,SFR1,NEK1,NFIA,NFYA,NHLH1,NOS1,NTRK2,NUCB2,OPCML,OPHN1,ZNF713,P2RX7,ZDHHC22,GLIPR1L2,PDE4A,ENPP2,PFKFB3,GDAP1L1,TMIE,PIK3CD,CCSER2,FAM216A,PLP1,PMP2,PMP22,FAT3,PPARA,PCDHB17P,CRLS1,PPP2R5E,RASGEF1B,PRKACB,PRKCZ,PROX1,MASP1,VPS13C,LAMA1,SIDT1,GON4L,CNTLN,UHRF1BP1,BDNF-AS,ELOVL2,TMEM260,OCIAD1,PTPRG,PID1,FAT4,NWD1,RASGRF1,RASGRF2,BSDC1,SLC6A15,GTDC1,RPRD1A,EXD2,GSTCD,CCDC102B,TMEM100,EPHA10,RPL15,ARMH4,RPS20,SYNDIG1,ZNF568,STX1B,ZNF331,DGLUCY,CSRNP3,ATXN2,SCN3A,SCP2,SLC30A10,ZFP2,SOX6,TRIM46,MRAS,ITSN1,ASAP3,HKDC1,NLGN1,ST3GAL3,CTXN2,SLC1A3,WDR47,SEPHS1,SLC11A1,SLC14A1,ATF7IP,CPEB4,EPC1,SLN,INTS9,RIMS1,SNRPN,TMCC1,RBM34,SCN3B,TRERF1,TNIK,KDM3A,NMNAT2,PEG10,SPTAN1,KIF1B,COLGALT2,ERBIN,ELOVL4,DIP2A,NECAB1,SYNE2,ARHGEF9,C3orf70,TACR1,KAZN,EXOC7,CAMSAP2,CNTN2,VWA3A,WSCD1,DMXL2,SATB2,ZFP90,TCF7L2,TRIM2,WDR7,SYNE1,DOCK9,PUM2,TNS2,FRYL,HIF3A,SIRT1,CRB1,HHIP,SLC44A1,THRA,MTMR14,DDHD1,NPL,C9orf85,ZNF346,SYNPO2,TRIO,PDSS1,STXBP4,RFTN2,UBE3A,BEST1,P2RY12,CLDND1,ZIC3,KCNT2,ZNF138,REEP1,FTSJ1,SYNC,PRDM2,DNALI1,WIPF2,WNK3,DNAH10,CASC15,MSRB3,PIANP" MicroRNA hsa-miR-23c:TargetScan hsa-miR-23c TargetScan 3.27E-119 1.84E-115 2.98E-118 2.75E-117 261 926 "CLK4,C3orf14,ACTN2,PWWP2A,RNF150,NLGN4X,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,MTMR9,B3GALT2,CADM3,N4BP2L1,NOL4,ADAM23,NRP2,KSR1,JAZF1,FOXK1,MAP7,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,REPS2,MAGI1,DLGAP2,DLGAP1,CFL2,RAB3C,NRXN3,CLCN3,NRXN1,DNAJB5,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,CTNND2,GPSM1,PYGO1,GAPVD1,FRMPD4,PHF19,MAML1,DAPK1,PITPNC1,DNAJC6,KIAA0753,G3BP2,FAM107B,ARNT2,DLG2,DLX1,RAB39B,CPEB2,DTNA,DYRK1A,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,ELAVL4,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,KIAA1109,FGF14,ANKFY1,CELF1,PNMA2,FUT9,PHYHIPL,GAB1,CHL1,GABRB1,GABRB3,NEK6,NCKAP1,GAP43,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,GPR22,NUDT21,EML4,PCLO,RFFL,GRM5,IL1RAPL1,HAS2,FRMD5,BACH2,SCRG1,HNF4G,NEGR1,HTR2A,DOCK7,IL6R,JAK1,KCNB1,KCNH1,KCNK1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MDFI,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,NAP1L1,NDUFA5,NFIA,ALDH1L2,NFIX,NOVA2,NRGN,OXTR,PAK3,PBX1,PDE3A,PDE3B,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,FTO,EPN1,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,RIMKLA,PTGR2,RXRG,AP1AR,SAFB,SATB1,ATXN1,ATXN7,SCN2A,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,CTXN2,DZIP1,EPN2,RUFY2,BTBD7,CPEB4,EPC1,MBD5,PALLD,FAM126B,POGZ,LRRC4,FGD4,NUDT10,MMS19,PJA1,CAMSAP2,KIAA1107,ANO4,ATMIN,SATB2,RALYL,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,HHIP,NACC2,CBX5,ASXL3,DOK6,CADM1,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-23a-3p:TargetScan hsa-miR-23a-3p TargetScan 3.27E-119 1.84E-115 2.98E-118 2.75E-117 261 926 "CLK4,C3orf14,ACTN2,PWWP2A,RNF150,NLGN4X,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,MTMR9,B3GALT2,CADM3,N4BP2L1,NOL4,ADAM23,NRP2,KSR1,JAZF1,FOXK1,MAP7,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,REPS2,MAGI1,DLGAP2,DLGAP1,CFL2,RAB3C,NRXN3,CLCN3,NRXN1,DNAJB5,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,CTNND2,GPSM1,PYGO1,GAPVD1,FRMPD4,PHF19,MAML1,DAPK1,PITPNC1,DNAJC6,KIAA0753,G3BP2,FAM107B,ARNT2,DLG2,DLX1,RAB39B,CPEB2,DTNA,DYRK1A,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,ELAVL4,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,KIAA1109,FGF14,ANKFY1,CELF1,PNMA2,FUT9,PHYHIPL,GAB1,CHL1,GABRB1,GABRB3,NEK6,NCKAP1,GAP43,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,GPR22,NUDT21,EML4,PCLO,RFFL,GRM5,IL1RAPL1,HAS2,FRMD5,BACH2,SCRG1,HNF4G,NEGR1,HTR2A,DOCK7,IL6R,JAK1,KCNB1,KCNH1,KCNK1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MDFI,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,NAP1L1,NDUFA5,NFIA,ALDH1L2,NFIX,NOVA2,NRGN,OXTR,PAK3,PBX1,PDE3A,PDE3B,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,FTO,EPN1,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,RIMKLA,PTGR2,RXRG,AP1AR,SAFB,SATB1,ATXN1,ATXN7,SCN2A,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,CTXN2,DZIP1,EPN2,RUFY2,BTBD7,CPEB4,EPC1,MBD5,PALLD,FAM126B,POGZ,LRRC4,FGD4,NUDT10,MMS19,PJA1,CAMSAP2,KIAA1107,ANO4,ATMIN,SATB2,RALYL,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,HHIP,NACC2,CBX5,ASXL3,DOK6,CADM1,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-23b-3p:TargetScan hsa-miR-23b-3p TargetScan 3.27E-119 1.84E-115 2.98E-118 2.75E-117 261 926 "CLK4,C3orf14,ACTN2,PWWP2A,RNF150,NLGN4X,PCDH19,KCTD16,OSBPL8,ARHGAP20,DPP10,LRCH2,PKP4,APAF1,MADD,CASK,CDK13,PDE8B,NCOA1,MTMR9,B3GALT2,CADM3,N4BP2L1,NOL4,ADAM23,NRP2,KSR1,JAZF1,FOXK1,MAP7,RUNX1T1,CBLN1,LDB2,CCNH,CBFA2T2,REPS2,MAGI1,DLGAP2,DLGAP1,CFL2,RAB3C,NRXN3,CLCN3,NRXN1,DNAJB5,QKI,MAP4K4,CNR1,COL11A2,RCHY1,IGDCC3,SEC31B,AKAP12,HAPLN1,CS,LRIG1,CSNK1G3,IPCEF1,PPP1R16B,PLCXD3,CTNND2,GPSM1,PYGO1,GAPVD1,FRMPD4,PHF19,MAML1,DAPK1,PITPNC1,DNAJC6,KIAA0753,G3BP2,FAM107B,ARNT2,DLG2,DLX1,RAB39B,CPEB2,DTNA,DYRK1A,EBF1,EDNRA,HIPK3,KLHL5,EGR3,PLXNC1,ELAVL4,CALCRL,EIF1,ERBB4,CEP85L,ETV1,EYA1,PTK2B,CHST15,MED12L,KIAA1109,FGF14,ANKFY1,CELF1,PNMA2,FUT9,PHYHIPL,GAB1,CHL1,GABRB1,GABRB3,NEK6,NCKAP1,GAP43,GCNT2,FREM1,PCDH17,GHR,PPARGC1A,GLYR1,GPR75,KIAA1958,PRRC2B,GPR22,NUDT21,EML4,PCLO,RFFL,GRM5,IL1RAPL1,HAS2,FRMD5,BACH2,SCRG1,HNF4G,NEGR1,HTR2A,DOCK7,IL6R,JAK1,KCNB1,KCNH1,KCNK1,KCNK3,CREG2,KPNA5,IPO5,LSAMP,MARK1,MAT2A,MDFI,MEF2C,MEIS1,MEIS2,MGAT3,KITLG,MITF,AFF1,MPP2,MSI1,BLOC1S2,HS6ST3,MYO6,MYO9A,NAP1L1,NDUFA5,NFIA,ALDH1L2,NFIX,NOVA2,NRGN,OXTR,PAK3,PBX1,PDE3A,PDE3B,PDE4B,PDPK1,GNG2,PFKFB4,OLA1,PIK3C2A,FTO,EPN1,PPP2R5E,PPP3CA,PKIA,DIRAS2,DCHS2,CNNM2,ANKHD1,MTMR10,EML5,PTPRG,ACSS3,RAD17,MORC4,FIGN,PBRM1,CCDC82,C12orf49,CYB561D1,ROBO1,ROBO2,RIMKLA,PTGR2,RXRG,AP1AR,SAFB,SATB1,ATXN1,ATXN7,SCN2A,FNIP1,SEC14L1,CPEB3,AMBRA1,FBXO11,NLGN1,CTXN2,DZIP1,EPN2,RUFY2,BTBD7,CPEB4,EPC1,MBD5,PALLD,FAM126B,POGZ,LRRC4,FGD4,NUDT10,MMS19,PJA1,CAMSAP2,KIAA1107,ANO4,ATMIN,SATB2,RALYL,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,HHIP,NACC2,CBX5,ASXL3,DOK6,CADM1,EIF4ENIF1,PLEKHH2,MICU3,NDRG4,REEP1,CADM2,PRDM10,JMJD1C,NETO1" MicroRNA hsa-miR-513a-3p:PITA hsa-miR-513a-3p:PITA_TOP PITA 3.88E-119 2.18E-115 3.54E-118 3.26E-117 240 778 "CSMD3,SLITRK1,ESYT2,NLGN4X,KLHL13,PCDH19,TAOK1,SPOP,ALCAM,FAM135A,DPP10,LRCH2,PKP4,LRRC4C,ARHGAP5,NCOA1,DYNLL1,STX16,ATP2B1,DCAF5,FUBP1,MTMR3,LDLRAD4,CACNB2,KALRN,TMEM257,ZMYM4,CCPG1,CIART,CFL2,FOXN3,SOCS6,CNOT8,KMT2C,NRXN1,QKI,SULT4A1,CNN3,IQCK,CREM,GDA,LRIG1,LRRC3B,CNTNAP2,SLITRK5,DOCK4,FRMPD4,TOX,LONRF1,MATR3,HP1BP3,SNAP91,MTX3,WDR20,DLX1,HS3ST4,DPYSL2,ABI1,ARRDC4,DYRK1A,SNX29,EFNB3,KMT5B,EIF4G1,ELAVL2,TMEM35A,EML1,PTK2B,HPCAL4,PSD2,AFF2,NBEA,FUT9,ZMAT1,STAG2,GABRA5,JPH4,WASF3,DNER,MSTN,AHDC1,PCDH17,PPARGC1A,DBF4,TNRC6A,PCDH11X,ZNF638,FERMT2,GPT2,GPM6A,GPR34,EML4,GRIA4,GRM7,ZBTB49,ZHX1,BACH2,HMGB1,HNRNPK,AGFG1,C5orf24,ZIC5,TJAP1,OLFM3,KCNK2,CREG2,KLC1,IPO5,SMAD1,MAP2,MAP4,MARK1,MEIS1,KITLG,MITF,AFF1,MXI1,MYCN,NEXMIF,NACA,NAP1L1,NCAM1,NEFM,NEK1,NELL2,NFIX,NOVA1,NPTX2,NRCAM,CHAMP1,OPCML,PCDH8,PCSK1,PCSK2,PDE4D,PFKFB3,CDK14,PIK3C2A,XRN1,PLCL1,LRP12,SH3KBP1,DRAM2,MINDY2,PPP3CA,PPP3CB,KANSL1,PKN2,RELN,VPS13C,SNRK,UHRF1BP1,PTPRD,PEX5,SUSD4,OXR1,ARID4A,RBBP6,ZYG11B,NUDT11,PBRM1,ZFHX4,FBXW7,SEMA6D,ATXN1,LRRTM4,SOX6,PPM1E,CPEB3,NLGN1,SLC1A2,FAM81A,PPP4R3A,SLC6A9,SNCA,SON,SOX1,SOX2,SOX5,MYCBP2,SPP1,KDM4C,KIF1B,ZBTB43,POGZ,EPB41L3,LARP4,NKAIN2,ERBIN,CEP68,TTBK2,STX1A,ARHGEF9,SYN2,SYPL1,SYT4,CAMTA1,TAL1,AGTPBP1,FBXW11,ATMIN,TCF4,SATB2,ZEB1,TRIM2,RPGRIP1L,TCF12,PUM2,DICER1,SLC44A1,HEY1,ZFP91,RUNDC3B,TRPS1,HIRA,FAM155A,SLAIN1,PITPNB,USP1,BCL2L13,MEAF6,CLDND1,XPO1,SF1,ZNF711,ZFAND5,SMARCAD1,SLC30A4,RNF103,FIP1L1,WNK3,SLC17A6,RGS7BP,FAM13C,FZD3,PAK5,KAT6A,SNX14,RNF146,CPNE4" MicroRNA hsa-miR-144-3p:TargetScan hsa-miR-144-3p TargetScan 4.08E-119 2.29E-115 3.72E-118 3.42E-117 236 751 "CPNE2,ARID1A,ELFN2,CCDC85A,AXIN2,GPR158,OSBPL1A,ALCAM,PCDH10,BEGAIN,DPP10,ANK2,ANK3,PPFIA4,PPFIA1,APC,ALS2,APP,CASK,MARCH3,DACT3,ATP2B1,ATP2B2,NOL4,KSR1,BMPR1B,DST,MTMR2,LDLRAD4,CACNA2D1,CACNB2,CALB1,CAMK2D,BRSK2,CBFA2T2,CDH2,CDH8,NOG,CFL2,CHN2,LHX2,DLGAP3,KIAA1549L,QKI,CNN3,ACBD5,C2CD2,HAPLN1,PPP1R16B,PUM1,CCDC144A,PYGO1,HDAC9,DNAJC6,JAKMIP2,MYEF2,CEP170,MAGI2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,DTNA,DYRK1A,EBF1,HIPK3,RBM12,PHF20L1,EGFR,MBNL2,ABI2,PLXNC1,GOLGA7,EIF4G2,EIF5,ELAVL2,RGS17,ELN,EPB41,MTSS1L,EPHA5,KCNMB2,EPS8,ERBB4,ETV1,ACSL4,DLC1,ATP8A1,MED12L,FOXG1,PSD2,DCTN2,CAMKK2,ATP2C1,KHDRBS3,GAB1,GABRA1,BRPF3,ARPP21,NCKAP1,FAXC,AHDC1,GLI2,RAB30,GNAL,GPM6B,GRIK2,GRIK3,NR3C1,GRM5,KIF3A,PTPN5,KAT7,FAM222A,KLF12,BACH2,MIER3,HMGCR,AGFG1,HSF2,C5orf24,PLD5,JAK2,KCNA1,CDH20,KCND3,KLHL23,KCNN3,KIF2A,KIT,CYP27C1,INSYN2,LIFR,NCOA7,LSAMP,MARK1,MATN2,MBNL1,MDM4,MEIS1,MEIS2,KITLG,MITF,MSI1,JAKMIP3,RSPO2,MYCN,MYT1,NEUROD1,NFIA,NFE2L2,NOVA1,NPTX1,CNTN3,PCSK5,PDE3B,PDE4A,PDE4D,GPR85,PIK3C2A,PCDH18,PRRX1,FAT3,PPP2R5E,PKIA,PROX1,PTCH1,PTHLH,FAT4,RASGRF1,KHDRBS2,REV3L,FIGN,RFX3,NUDT11,PBRM1,ROBO2,RORB,FBXW7,LGR4,SALL1,ATXN1,SCN2A,SCN8A,CPEB3,MAGI3,FNDC3A,BTBD3,EPN2,CCDC88A,ATF7IP,CXXC4,LIMCH1,FAM126B,KDM3A,ARHGAP26,CDK19,LMO3,RGL1,AJAP1,FAM168A,PRRC2C,ADAMTS17,ANKRD28,ANKRD12,MCF2L,CAMSAP2,FBXW11,MGRN1,RPGRIP1L,NSD1,PUM2,CRTC1,GPRIN3,FRYL,NACC2,DDHD1,HEY2,KAT6B,RASD2,DOK6,RGMB,CADM1,FLRT2,KCNK12,FMN2,NDRG4,DPYSL5,RGMA,NAV3,KAT6A,PHTF2,ADAMTSL3,NETO2" MicroRNA hsa-miR-548e:PITA hsa-miR-548e:PITA_TOP PITA 4.62E-119 2.60E-115 4.20E-118 3.87E-117 247 827 "KCNH8,CSMD3,FMNL2,ADCY2,CCDC85A,USP31,NLGN4X,AP2A1,ZNF608,INTS2,HECW2,PCDH19,TBC1D14,OSBPL8,LRRC7,AMPH,CDC42BPA,ALS2,CDC14B,TMEFF1,ZFYVE28,CDK13,MARCH3,DDX3Y,SLC4A4,ATP2B1,ADGRB3,CDK5R1,SYNJ1,ARHGEF7,FUBP1,NIPA1,WASF1,CACNB4,CALB1,CALM1,PTBP2,CANX,RUNX1T1,SEPT7,CDH10,CLGN,NOG,SRSF11,SOCS6,LHX2,NRXN2,CLTC,FAM19A5,QKI,NIPBL,BAG4,ACBD5,CLOCK,CDC42BPB,CREM,CREB5,CRMP1,ATRNL1,ERC2,PLCXD3,CTNND2,ST18,HDAC4,LONRF1,MATR3,DGKB,TOMM20,MYEF2,ZC3H11A,DDX46,G3BP2,FAM107B,DMD,USP3,DSCAM,DYRK1A,HIPK3,RBM12,EFNB3,KMT5B,ABI2,EIF4G2,ELAVL2,STARD3NL,EIF1,EPB41L1,TAOK3,ATP8A1,FGF13,FGFR3,SUCO,FOXO3,FAM49B,DACH2,B3GAT1,STAG2,GABRB3,GABRG2,HBS1L,MSTN,AHDC1,GLS,TNRC6A,DCLK2,FERMT2,GPT2,PCLO,GRB10,RNF165,PTPN5,SOX21,PSIP1,GYG1,BACH2,MIER3,HLF,NEGR1,SMAP1,BRINP3,LRRTM3,KIF2A,KIF5C,NCOA7,SMAD1,MARK1,MBNL1,MITF,MSI1,MYO5A,NEXMIF,MYT1,NFIA,SETD4,CNTN3,PCSK1,PDE4D,ENPP2,GPR85,CDK14,PIK3R1,CCSER2,RETREG1,KCTD15,SCHIP1,POU3F2,PPARA,PPP2R2B,PPP2R5E,KANSL1,GDPD1,PTCH1,PTK2,FAM120C,TTC13,RAB5B,PID1,CEP97,ARID4A,RBBP8,RADX,ZYG11B,FIGN,RGS3,ZFHX4,ROBO2,FBXW7,RTN1,CSRNP3,ATXN1,CPEB3,CHD9,FBXO11,FNDC3A,NLGN1,PPP4R3A,WDR47,SLC8A1,CCDC88A,CPEB4,GKAP1,PDZD2,WDTC1,SOX1,MYT1L,ZCCHC24,SOX11,SOX15,LMO3,SRPK2,TAB2,CLASP2,EPB41L3,SS18,ERBIN,ST5,RGL1,PLCB1,SYT4,ANKRD12,CAMTA1,CAMSAP2,WWC1,TBL1X,TCF4,ZEB1,TRIM2,DOCK9,RALYL,TMEM121,ZFPM2,TGFBR3,SLC44A1,DDHD1,TLR4,ERCC6L2,KCNE5,TUB,TUBB2A,RPRM,AMOT,FLRT2,WIPF1,NSD2,ZBTB14,ZNF711,ZFAND5,SMARCAD1,WNK1,CA10,PMEPA1,EMSY,CSDE1,STOX2,NAV3,SNX27,KCNAB1,PCBP4,WNK3,PDSS2,GOPC,PAK5,HNRNPA3,MSRB3,FRMD6,RNF146,SOCS4" MicroRNA hsa-miR-4274:mirSVR_lowEffct hsa-miR-4274:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.98E-119 2.80E-115 4.52E-118 4.16E-117 322 1411 "CSMD3,NDRG2,GALNT16,AXIN2,SLC12A5,AP2A2,HACE1,ALAD,USP35,BCAR3,CARNS1,PCDH10,FAM135A,OGT,ANK3,PHF12,APBB1,APC,APP,SHTN1,AQP6,MIER1,ARHGAP5,CAPRIN2,INSYN2B,ATM,EIF4G3,ATP1B3,SLC2A11,BACH1,NRP2,SYNJ2,ARHGEF7,GYG2,BTRC,CALB1,KALRN,PTBP2,CAMK2G,SPAG9,CBLN1,CLDN10,MTMR7,SLC16A4,C1orf52,SEPT7,CDC25B,LARGE1,CDO1,CCPG1,SRSF11,LHX2,KMT2C,RAB33A,NRXN3,FAM19A5,DNAJB5,COL4A5,COL9A2,MAGED1,RCHY1,AHCTF1,FAM171B,SEC31B,CREM,CSF1,LRRC3B,CSNK1E,KIAA0040,RIMS2,HDAC9,ARHGAP32,ZNF337,MATR3,KIAA0586,MAML1,IP6K1,BRINP1,ARMCX2,SPATA2,ZBTB24,MYEF2,TMEM130,SMG7,SNAP91,RABGAP1L,FAM107B,CCDC3,GRIN3A,RAB39B,DMD,DMPK,SLC29A4,DMTF1,DTNA,ABCC5,DNM1L,EDNRB,ATL1,HIPK3,FRY,PHF20L1,AASS,SORBS3,PAN3,LRRC17,EPHA5,EPHB1,GPHN,ADGRV1,FAM198B,EFEMP1,FDFT1,KIAA1109,FGF13,FHL1,SEC23B,IP6K2,SYNCRIP,AGAP3,WDR83,UFM1,ATP6V1H,NSG2,STAU2,NRG3,MPP6,GABRA2,GABRA5,TRAF3IP2,ZNF274,IP6K3,NCKAP1,IQGAP2,DISC1,ATP8A2,GART,LRRC37A6P,SESN1,PPARGC1A,CRCP,MSL3,PCDH11X,STARD3,GPD2,STMN2,PLCD4,GSTM5,LINC01102,HMGB1,AGFG1,SHISA6,LRRCC1,ZNF385B,LAMP2,CAMK2N2,LIMS1,HECTD2,MATN3,MBNL1,SYT9,LRP1B,SRSF12,KCTD6,MIA2,MMP16,WDR49,ADAM22,CTNNA3,SAMD14,MYO9A,OTOGL,NFE2L2,NOVA1,NTRK2,NUCB2,GPR88,OPRL1,PAH,PCSK5,BEST3,PFKFB2,NLE1,PMP22,MAPKAP1,FAT3,PPM1B,LRRN3,PPP3CB,PRKACB,EPDR1,PROX1,PRPSAP2,MASP1,MDGA2,BDNF-AS,MTMR10,ZSCAN32,PTPRD,PID1,KHDRBS2,RET,GTDC1,RGS4,SLC25A36,CCDC82,KLHDC8A,GSTCD,ZC3H14,HUNK,ZNF568,RYR3,FAM192A,FOXRED2,SALL1,SEMA6D,SATB1,SCN8A,FAM102A,SH3GL2,FBXO11,NUBPL,CLSTN1,WDR37,RPH3A,SLC6A1,ARHGEF40,KBTBD4,EFHD1,CXXC4,GKAP1,CDK5RAP2,SMARCE1,ANKRD36,LIMCH1,RIMS1,USP33,FAM219A,TRERF1,SOX5,MYCBP2,TEX2,ZNF423,ZC3H13,DBNDD2,C11orf87,ITPRID2,SSPO,MAPK8IP3,STAU1,ZSCAN29,TTBK2,KANK1,NSFL1C,PRRC2C,ADAMTS17,SYT1,CAMTA1,WWC1,FBXW11,SATB2,WASHC4,SYNE1,OBSL1,ARHGEF12,FRYL,CYB561A3,PMS2CL,SIRT1,C18orf54,AP4E1,HHIP,AKTIP,THBS4,NACC2,HEY1,TJP1,BEX4,KCTD2,TNFRSF1B,TPD52,RASD2,DOK6,ZNF384,TRIO,ZMYND8,DCBLD1,TSN,ANKRD20A2,TSC1,ZKSCAN5,UCHL1,SLAIN1,PITPNB,FLRT2,USP1,TOM1L2,VLDLR,WIPF1,P2RY12,CLDND1,ZIC3,ATP6V0E2,CELF4,FSTL5,EML6,ZNF189,MAP3K12,SLC38A1,CSDE1,EVI5,ADAMTS9,TMEM178A,PDSS2,DOCK8,RTN4,PAK5,RNF170,NETO2,CBLN2,SLC4A10,JPH3" MicroRNA hsa-miR-29b-2*:mirSVR_highEffct hsa-miR-29b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.46E-119 3.07E-115 4.94E-118 4.55E-117 325 1437 "SDE2,SYN3,CLK4,XKR4,FMNL2,ADARB2,PWWP2A,KIAA1211,HECW2,OSBPL6,CC2D2A,LRRC7,ALAD,ALCAM,ABCD2,UNC79,OGT,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ALS2,AQP4,SPTBN4,CCAR2,DDX3Y,STX16,N4BP2L1,DPY19L3,SNAI3-AS1,SEC11C,CFLAR,SYNJ2,KALRN,PTBP2,TRIM41,CAST,RUNX1T1,CCKBR,INA,CDH8,CDH10,ZMYM4,L3MBTL4,MAGI1,CASC2,CNOT8,RAB33A,IGFBP7-AS1,PPT2,DGCR9,MAP4K4,CNGA3,CNTN1,RTTN,CP,SLC35F1,FAM171B,ENTPD4,HAPLN1,HINFP,ARHGEF10,CSNK1G3,ATRNL1,CNTNAP2,CTH,ARHGEF4,NRSN1,PPP6R2,CYBB,DOCK4,EARS2,TBC1D5,MATR3,PABPC5,ARMCX4,ARMCX2,C8orf34,DDX46,RHOBTB1,RAB39B,DNAH9,RPS6KL1,DMTF1,DSCAM,ARRDC4,GOLT1B,USH1C,FAM135B,EDNRA,FRY,EFNA3,RBM12,PHF20L1,ABI2,GOLGA7,MRNIP,CALCRL,DCTN4,EIF1,EPHA5,EPHB1,KCNMB2,TMEM74,VPS26C,TLR7,F5,CLVS1,ZNF461,CACNG3,FCGR1A,KAT8,GORAB,MED12L,GTF2IRD2,MEX3B,EVL,SGIP1,SLC37A3,TPK1,NRG3,ZNF512,PHYHIPL,RAPGEF6,ARPP21,ZNF234,ZNF559,C15orf41,DNER,PCDH17,MALT1,BRD8,GK,TCERG1,GLRB,TNRC6A,MSL3,PCDH11X,CBX1,GNAS,EML4,CECR2,GRIA4,GRIK2,GRM1,TMEM25,IRAK3,RASSF8,NXPH2,HNF4G,C9orf129,ZDHHC15,NKD1,ZIC5,LRRCC1,IL11RA,JAK1,OLFM3,KCNC2,KCND2,KCNN3,KIF5C,STXBP5,TTYH2,LMO2,HECTD2,ARHGAP12,NAT8L,MBD1,MBNL1,SYT9,MEIS1,C10orf105,FXYD6,NCAM1,NEUROD1,NF1,HCN1,NTRK3,TBC1D25,IGSF11,ZNF713,PCSK1,PCSK5,PDE3A,ENPP2,GNG2,SERPINE2,ANLN,ZNF655,A2ML1,RETREG1,PLP1,SMIM7,MTRF1L,ANKRD16,EXOSC10,SDK2,ING3,FA2H,PPM1B,PPP3CB,PRKACB,PKN2,HYDIN,PROX1,MDGA2,WDR25,MTMR10,PXK,TMEM260,PTPN13,PTPRG,PTPRH,PTPRO,ACSS3,CCDC40,RAD52,SH3TC2,NWD1,OXR1,RASGRF1,RASGRF2,FEZF2,KHDRBS2,SLC6A15,TRIM68,REV3L,GTDC1,RIC8B,PBRM1,ZNF532,ROBO1,RPE,MCMBP,WLS,RTKN,ZNF568,CCDC112,AP1AR,DGLUCY,SARS,SATB1,LRFN5,SCN2A,ITSN1,SHC4,HKDC1,MAGI3,AMBRA1,NLGN1,DZIP1,BTBD3,FAM214B,SCMH1,BTBD7,ZNF667,SMARCD3,LIMCH1,ZNF415,RBM26,NPAS3,POGZ,STOX1,SAMSN1,SSTR2,ERBIN,DIP2A,KANK1,FGD4,VPS13A,SYT4,DDHD2,ADGRL3,AGTPBP1,TBCEL,IQCE,SIN3B,CUX2,SYNE1,TMEM151B,RALYL,PCDHB9,TEX15,SIK3,SIRT1,CRB1,LEFTY2,GPR161,AKTIP,CDH22,THRA,NR2E1,HEY2,TMPO,CSMD1,TPD52,TPM1,ZNF384,METTL3,PRMT8,TRPC3,TTC3,TMEFF2,UGT8,FAM181B,WIPF1,SLC13A3,XRCC4,KCNT2,ZNF540,ATP6V0E2,FTSJ1,SYNC,UPF3A,WNK1,SLC30A4,PRTFDC1,RNF103,SCG2,WNK2,SLC17A6,C12orf4,HNRNPA3,NUP214,FRMD6,IFT88" MicroRNA hsa-miR-217:mirSVR_highEffct hsa-miR-217:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.76E-119 3.24E-115 5.21E-118 4.80E-117 306 1278 "CLK4,CSMD3,GALNT13,INTS2,MTUS1,TXNDC16,CC2D2A,LRRC7,ABCD2,ALK,AMPD3,OGT,CDC42BPA,ANK3,PKP4,UPRT,ALS2,CACHD1,SFMBT2,TMEM263,ZFYVE28,ASPH,CCAR2,ATM,SLC2A11,B3GALT2,N4BP2L1,ATP6V0A1,ADGRB3,ZNF599,DST,CACNA1E,CALM1,METTL6,LRBA,SEPT7,SRSF11,CHN2,CASC2,NDST3,TJP2,NIPBL,AKAP6,SLC25A27,AHCTF1,ZFP28,MFSD4A,FAM171B,RBM39,AKAP12,CS,CSF1R,LRRC3B,ATRNL1,PLXNA4,PHF14,NRSN1,ST18,ZSCAN23,USP6NL,EDRF1,CCDC144A,KIAA0408,DOCK4,HDAC9,KIAA0586,KCTD8,TOMM20,BRINP1,C8orf34,ZEB2,MYEF2,CNIH3,COPS7A,KIAA0319,ALKBH8,SPOCK3,SV2A,G3BP2,RABGAP1L,CHRDL1,DYRK1A,ABCC9,GOLT1B,EDIL3,EDNRA,SYT15,YAF2,SUGP2,EXTL2,ADGRV1,ACSL4,CORO2B,DLC1,CHST15,TOMM40L,SLC9B2,FGF11,FOXO3,ATP13A4,NOP56,TACC2,SORBS1,SMC2,FAM49B,ZNF605,DACH2,SARAF,TMEM151A,ZMYND11,GALC,SIGLEC8,ATP8A2,NEU3,BRD8,RAB30,GLRB,GLS,FERMT2,ADGRA3,GPM6A,GPR22,CNTRL,RAPGEF4,GRIA2,GRIK2,HAS2,MIER3,HLF,HNF4G,NEGR1,C5orf24,DOCK7,LIX1,IL6ST,IL11RA,ITGAV,KCND2,KCNJ16,KCNMA1,STXBP5,LAMP2,HECTD2,NCOA7,SMAD9,MAP2,CHIC1,TM6SF1,POC1B,CD200,ZNF680,MRPL42,CCDC80,BCO1,ZNF92,MTTP,MYO9A,NAP1L2,NEUROD1,NF1,NME4,NOVA1,NRCAM,NUCB2,SETD4,CLDN11,GPR137C,CNTN3,PCDH8,PCDH9,PCMT1,PDE4B,GPR85,BEST3,PFKP,NALCN,ANLN,PURG,TRHDE,SPATA6,MED1,PPM1B,PKN2,SLC26A11,GDPD1,SAMD9,VPS13C,MDGA2,PTCH1,TMEM260,MARCH1,FAT4,RAP1GDS1,ZNF493,GTDC1,FIGN,RFX3,RGS12,SEC61A2,RPRD1A,ZFHX4,CCDC82,CARF,RORB,NEK11,ARMH4,ATP8B4,ACER3,ABCA11P,ATAT1,RTN1,ZNF568,SEMA6D,SATB1,LRRTM4,SCP2,ELMOD1,SFPQ,SUPT20H,HSPA4L,SGK1,DOCK10,NTNG1,FBXO11,FHOD3,SLITRK3,ZNF365,BTBD3,WDR47,RUFY2,SLC6A1,SEPHS1,SLC14A1,SLC15A2,BTBD7,TET1,GKAP1,SORCS3,LIMCH1,KIF13A,SNRPN,KDM4C,ZNF423,NPAS3,LHPP,PBLD,ITPRID2,ZNF302,SEPT8,CEP68,TTBK2,AJAP1,ZC3H4,NUDT10,EXOC7,UNC5D,ADGRL3,TBCEL,FBXW11,ATMIN,ZEB1,RPGRIP1L,SYNE1,AKNA,SLC35G2,TEX15,SIRT1,ZFPM2,ASXL3,DDHD1,TLR4,TPD52L2,TRH,TMPRSS5,SSBP2,TUBB1,MEAF6,VSNL1,RICTOR,SF1,PCDH20,ZBTB14,ZNF711,ZNF708,ZNF19,MICU3,ZNF45,DHX33,INTS3,WNK1,STOX2,PRDM8,TMEM178A,PCDH15,NAV3,SNX27,C12orf4,PDSS2,EPM2A,GOPC,HNRNPA3,FBXO36,SLC39A12,FXR1,GAN,SENP7" MicroRNA hsa-miR-548s:mirSVR_lowEffct hsa-miR-548s:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.37E-119 3.58E-115 5.75E-118 5.30E-117 359 1738 "CPNE2,TTYH1,DGCR6,ABR,SYS1,ADCY6,TMCC3,ADD3,SLC12A5,ERMN,RNF150,PTCHD1,GPR158,KLHL13,OSBPL1A,DISP3,SMIM17,CEP126,FAM135A,SYT13,FGD2,USP28,PHYHD1,VAT1L,AQP6,TMEM263,CHID1,ATM,SLC4A4,ATP1B3,STX16,ATP2B1,SLC2A11,ATP6V1G2,BBS2,BCL2L2,DNAJC27-AS1,KSR1,LINC00906,SCAPER,AP1M1,MMD2,BTRC,LURAP1,KALRN,CANX,MAP7,PRC1,LGI1,IGFN1,PLEKHB1,SYNPR,CPNE6,CLTA,CLTC,SRP14-AS1,ARHGEF6,CNTN1,PCYT1B,LETMD1,ABI3BP,ZFP28,IGDCC3,SLC35F1,SH2B1,HINFP,CS,CSF1,SUSD5,IPCEF1,RASGEF1C,SDC3,GREB1,CFAP61,KATNAL2,GAPVD1,EARS2,ZNF337,RASSF2,TBC1D5,CTIF,AIF1L,GIT2,ARMCX4,FBXL5,KIAA0319,CEP170,GUCD1,SGSM2,RABGAP1L,DLX1,RAB39B,TRAPPC9,CASP8AP2,DPP6,DRD1,ARRDC4,DNAJB6,DYRK1A,ABCC5,DNM1L,AASDH,SNX29,EDNRB,RASGRP1,TMTC1,SIDT2,SUGP2,MRO,MBNL2,AASS,ENPP6,NCALD,PIPOX,VPS26C,ADGRV1,ZNF461,FCGR3A,GTF2IRD2,OLFM1,FGFR1,FOXF2,SYNCRIP,ANKFY1,PSD2,TMEM107,TRIM16,ERGIC3,DACH2,CGREF1,ST6GALNAC3,MSANTD4,FYB1,GABRA3,GABRB3,GABRG1,GALC,RAPGEF6,ZNF559,WASF3,CPLX2,KIAA1841,ALDH1L1,GCNT2,PPARGC1A,KIRREL3,CRCP,ZNF638,GNAS,LNX1,GOLGB1,GPD2,PCLO,ADAMTS8,ATE1,PRDM5,GRM7,LINC00839,GUCY1A1,MAEL,NXPH2,TNFAIP8L3,MIER3,SYNPO,ZDHHC15,HSF2,ATCAY,SOWAHA,IGF1,ZIC5,DOCK7,SCIN,ITGAV,ITPKB,SLC35G1,KCNB1,KCNJ10,KCNK1,KCNN1,GATD1,KTN1,STMN1,PAXBP1,NCOA7,LOC100128239,MAP4,MBP,TM6SF1,SRSF12,MID1,PPM1L,AFDN,JAKMIP3,MSR1,PABPC1L2A,NCAM1,NF1,NKX2-2,NPR2,NTRK2,IGSF11,ODF2,OGG1,OPCML,OPHN1,KCNK10,TREM2,PCDH9,GDAP1L1,CAMKV,TMEM38A,PLCB2,PLIN1,FXYD1,PLXNB1,PURG,SCHIP1,ING3,FAT3,PTPA,PRKCG,PRKCZ,DCHS2,QRICH1,PIGG,UHRF1BP1,PTHLH,PTPRD,CASTOR1,PTPRG,ACSS3,ZNF793,OXR1,RASGRF2,MSANTD2,SLC6A15,TRIM68,RGS4,ARHGEF10L,SEC61A2,GSTCD,ROBO1,TMEM206,NEK11,RPL15,UEVLD,FBXW7,MCMBP,STK32B,RPS20,HSD11B1L,WLS,RTKN,KCNIP2,ZNF331,CCDC112,FAM192A,ATXN1,HOGA1,SCP2,RASA3,SCAF8,ZFP30,SH3BP2,FAM102A,DZIP1,DHX30,PKNOX2,SLC8A3,SHANK2,SLC14A1,ELMO2,CDK5RAP2,RIMS1,SNCA,TMCC1,DOP1A,SON,SOX2,IZUMO4,ERC1,DDN,POGZ,ITPRID2,SSTR2,LRRC4,SULF2,KLHL7,ZFR2,SYNE2,NUDT10,TACC1,TACR1,TBCEL,TMEM136,ANO4,KIAA0930,TPCN2,SYNE1,DOCK9,SLC19A3,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,HIF3A,CRB1,LEFTY2,AP4E1,ARL10,TIMP4,ASXL3,TLL2,BHLHB9,ERCC6L2,TPD52,TPM2,C9orf85,TPM4,ELP5,TRIO,TRPS1,ZMYND8,FNDC5,HIRA,FAM155A,UGT8,PLPPR2,CCDC136,VLDLR,CLDND1,SLC13A3,SF1,ZNF540,TMEM237,PCBP1-AS1,GDPD5,LINC02210,SIGLEC10,PCDH15,TRIM16L,WNK3,MVB12B,EPM2A,DNAH10,UBE3B,CAMK1G,NUP214,TRAM2-AS1,ZNF248,RNF170,VANGL2,FRMD6,IFT88" MicroRNA hsa-miR-302c:mirSVR_highEffct hsa-miR-302c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.76E-119 3.80E-115 6.10E-118 5.62E-117 330 1481 "CLK4,KIAA1211,PTCHD1,ADRB2,MTUS1,GPR158,PCDH19,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,MARK4,ASPH,EIF4G3,STX16,DPY19L3,ATP6V1G2,BACH1,MPDZ,DCAF5,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,THSD7A,AIFM1,MAGI1,CLGN,CFL2,CHN2,CNOT8,TAOK2,IGFBP7-AS1,ABCG2,C4orf33,QKI,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,SNCAIP,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,TOX,KIAA0586,DGKG,DCC,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,RABGAP1L,HS3ST4,HS3ST2,DNM2,DMTF1,DRD1,DTNA,GOLT1B,E2F5,E2F6,WDPCP,EDN3,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,VPS26C,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,ZNF512,MEGF11,CAB39,ZMYND11,ARPP21,IGSF5,TUBGCP4,ADAM28,GGTA1P,PPARGC1A,COPS8,TOX3,TNRC6A,GLUL,ZNF638,MAP7D2,POLL,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,MAEL,UBE2QL1,HPS5,HMGB1,ZDHHC15,HSP90AA1,SMAP1,MSL1,IDH3B,JAK1,OLFM3,KCNMA1,KCNN2,CYP27C1,SYTL4,HECTD2,NCOA7,LSS,ZNF667-AS1,MARK1,MDM4,MEIS1,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPHN1,GPR137C,PCDH9,PCSK2,PDCD2,PFKP,ZDHHC8,PLCL1,JAKMIP1,HMGCLL1,PRIMPOL,TRHDE,PRRX1,SPATA6,DRAM2,PPP3CB,RASGEF1B,PRKACB,PKN2,GRAMD1C,MASP1,SNRK,CNTLN,PTHLH,PXK,TMEM260,PTPRO,RAB5B,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,GTDC1,FIGN,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,TMEM100,MCMBP,LGR4,RPS20,RTN1,AMER2,SCN2A,IL17RB,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,NUBPL,CLSTN1,WDR37,SLC1A6,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,INTS9,RCOR3,CMTR2,SNRPN,UNC80,RBM34,MYT1L,SOX2,TNIK,TEX2,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,POGZ,SAMSN1,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,UNC5D,ADGRL3,TBCEL,CUX2,TCF7L2,ZEB1,SZT2,RALYL,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,GZF1,TIAM1,NACC2,NR2E1,TNS1,TPD52L2,RGMB,PRMT8,TRPC1,PPIL6,FAM181B,ZNF709,VLDLR,TBC1D15,PCDH20,KCNT2,TRIM9,FMN2,LYPD6,LAMP5,SYNC,CADM2,PRDM2,PRTFDC1,RGMA,PRDM8,PRDM10,RNF103,FIP1L1,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-101-3p.2:TargetScan hsa-miR-101-3p.2 TargetScan 8.18E-119 4.60E-115 7.37E-118 6.79E-117 243 801 "ARID1A,NDRG3,ELFN2,CCDC85A,AXIN2,OSBPL1A,ALCAM,PCDH10,BEGAIN,DPP10,LRCH2,ANK3,PPFIA4,PPFIA1,APC,APP,MIER1,MARCH3,DACT3,RASL11B,ATP2B1,ATP2B2,NOL4,BACH1,BMPR1B,DST,FUBP1,MTMR2,LDLRAD4,CACNB2,CAMK2D,BRSK2,RUNX1T1,INA,CBFA2T2,DGKI,CD81,CDH2,KCNAB3,CDH8,MAGI1,NOG,DLGAP3,NRXN3,QKI,HAPLN1,PPP1R16B,PYGO1,HDAC9,JAKMIP2,MYEF2,MAGI2,G3BP2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,DYRK1A,ABCC5,EBF1,HIPK3,FEM1B,FRY,EFNB3,PHF20L1,MBNL2,ABI2,PLXNC1,EIF4G2,EIF5,ELAVL2,RGS17,ELN,MTSS1L,EPHA5,ENPP6,EPS8,ERBB4,ETV1,ACSL4,DLC1,ATP8A1,MED12L,MEX3B,FOXG1,PSD2,HVCN1,ATP2C1,GAB1,GABRA1,ARPP21,NCKAP1,FAXC,GFRA1,PPARGC1A,GLI2,GOLGB1,GPR37,CECR2,GRIA2,DIDO1,GRIK2,NR3C1,GRM1,GRM5,PTPN5,KAT7,FAM222A,PACSIN2,KLF12,BACH2,ELOVL5,HMGCR,HNRNPK,AGFG1,JAK2,KCNA1,CDH20,KCND3,KCNN3,KIF2A,KIT,CYP27C1,LIFR,PAXBP1,MARK1,MBNL1,MEIS2,KITLG,MITF,MSI1,JAKMIP3,RSPO2,MYCN,NAP1L1,NCAM2,NEUROD1,NOVA1,NPTX1,CHAMP1,CNTN3,PCSK5,PDE4A,PDE4D,GPR85,PIK3C2A,GPSM2,PLCL1,PCDH18,LRP12,PRRX1,FAT3,NXPH1,PPARA,PPP2R5E,PPP3CA,PKN2,MAPK8,PROX1,MDGA2,PTCH1,PTHLH,PTPN13,PTPRG,PTX3,PEX5,FAT4,RASGRF1,KHDRBS2,REV3L,GTDC1,FIGN,RFX3,PBRM1,ROBO2,FBXW7,ACER3,RYR3,SALL1,SATB1,ATXN1,SCN2A,SCN8A,ITSN1,PPP1R9A,NTNG1,MAGI3,FNDC3A,R3HDM2,BTBD3,EPN2,ATF7IP,CXXC4,LIMCH1,MBD5,FAM126B,KDM3A,ARHGAP26,NPAS3,NFASC,LMO3,RGL1,AJAP1,FAM168A,PRRC2C,ADAMTS17,PLCB1,ANKRD28,ANKRD12,MCF2L,CAMSAP2,FBXW11,MGRN1,ACSL6,DMXL2,NSD1,PUM2,FRYL,DICER1,ITGB3BP,NACC2,DDHD1,BHLHB9,HEY2,KAT6B,RASD2,CADM1,PITPNB,FLRT2,KCNK12,FMN2,NDRG4,RGMA,NAV3,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,NETO2,GAN,PRRT4" MicroRNA hsa-miR-486-5p:mirSVR_lowEffct hsa-miR-486-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.60E-119 5.39E-115 8.63E-118 7.95E-117 315 1355 "CLK4,ACTN2,CSMD2,ARID1A,FMNL2,BRAP,SLC12A5,SORCS1,DPY19L2P4,MTA3,AP2A2,ZNF608,MTUS1,HECW2,OSBPL8,SRPX,CDC42BPA,ANK1,ARMC12,PHF12,PPFIA1,PKP4,APC,FAM131A,CACHD1,APP,CDK10,MADD,SPTBN4,MARK4,CAPRIN2,NCOA1,DDX3Y,ATP2A2,NOL4,BACH1,MPDZ,RGS9,BCL7A,SYNJ1,GYG2,PTBP2,CANX,CAST,CLDN10,KRIT1,USP2,CD86,SEPT7,LGI1,LARGE1,MAGI1,CLGN,CHN2,KMT2C,ZFYVE9,CNTN1,AKAP6,COL9A3,MYRIP,NCOR2,RGS6,LRIG1,CSNK1G3,ATRNL1,UBXN2A,CTH,RIMS2,BOC,HDAC9,ZNF337,IST1,HP1BP3,CEP170,FBXO25,PLPPR4,SV2B,G3BP2,GRIN3A,DYNC1I1,DMTF1,ABI1,DTNA,DNAJB6,KRBA2,EDN3,EFNA3,MRO,TENM1,ELAVL2,CERCAM,STARD3NL,C8orf37,EPB41L1,EPHA5,DENND4A,EYA1,EZH1,ABCA8,WAC,FKTN,SEC24B,FER,POLK,SUCO,TACC2,SMC2,UFM1,NPTN,SARAF,DOT1L,GABRA1,GABRA2,HRASLS5,CAB39,GAD1,ZNF274,ALDH1L1,AHDC1,BRD8,RNPS1,GLS,TNRC6A,KCNMB4,ZNF782,ATF7,STON1,EML4,DIDO1,GRIA4,NR3C1,FAM19A2,RABL2A,IRAK3,ARHGAP36,HLF,HMGB1,HNF4G,ICA1,ZIC5,USP54,IL11RA,ZNF385B,LRRTM3,KCNC2,KCNMA1,KLC1,CYP27C1,ARHGAP12,SMAD1,ZFYVE27,MAP6,MARK3,AQP11,MEIS2,MIA2,WDR49,JAKMIP3,MSR1,PTOV1,MYO7A,MYO9A,PABPC1L2A,NCAM2,NELL2,NF1,NFE2L2,VWA2,NRCAM,OCRL,ZDHHC22,PCSK1,PDE4A,NALCN,SNX10,ZFYVE21,NLE1,HMGCLL1,C11orf49,CDIP1,SCHIP1,PRRX1,RETREG2,SLC36A4,FAT3,NXPH1,PPP2R2B,PPP2R5C,PPP2R5E,PPP3CA,PRKCG,HYDIN,PSD,PTK2,PTPRD,RAP1GDS1,OXR1,ZYG11B,REV3L,ZNF532,CARF,ROBO1,ROBO2,RPE,SNX22,FBXW7,ATP8B4,HUNK,ATAT1,TRAPPC13,SALL1,FAM19A1,ELMOD1,SEC14L1,SOX6,MRAS,HSPA4L,SGK1,ZFP30,ITSN1,ARX,KIF16B,CPEB3,MAGI3,FBXO11,ST3GAL3,NUBPL,WDR47,SEPHS1,SLC8A1,CCDC88A,SLC9A5,NAPB,LIMCH1,RIMS1,SON,KDM3A,KDM4C,ZNF423,POGZ,SAMSN1,EPB41L3,LRRC4,MAPK8IP3,SEPT8,ZFR2,NUDT10,ANKRD12,TAF6,PDLIM2,ADGRL3,FBXW11,SMG6,ANO4,EHBP1,ACSL6,SIN3B,TCF7L2,ZEB1,WDR7,SYNE1,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,CRB1,TMOD1,TMPO,RIMBP2,CSMD1,KAT6B,TPM3,RGMB,ZMYND8,SSBP2,TTTY15,FAM155A,EIF4ENIF1,SLC35A4,UBTF,DNAJC12,FLRT2,BCL2L13,TBC1D15,WIPF1,ZNF781,CFAP298,PCDH20,ZIC3,TRIM9,ELFN1,CELF4,ZNF213,PMEPA1,EVI5,LMAN2L,TUBA1A,SIGLEC10,PCBP4,UBE3B,HNRNPA3,PHTF2,FBXO36,ADAMTSL3,JMJD1C,KLHDC1,NETO1,SOCS4,CPNE4" MicroRNA hsa-miR-223*:mirSVR_highEffct hsa-miR-223*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-118 5.79E-115 9.26E-118 8.53E-117 303 1256 "RALGAPA1,TMEM132B,GALNT13,PNMA8B,BEND6,KLHL13,WDR35,ABCD2,KIF6,DPP10,LRCH2,LCORL,PPFIA1,GPAM,LRRC4C,LGR5,MIER1,TMEFF1,ARHGAP5,ZBTB10,SLC4A4,EIF4G3,NRP2,SYNJ1,SYNJ2,FUBP1,WASF1,CALM1,CAMK2D,VXN,SEPT7,CDH2,LRRFIP1,LGI1,SRSF11,JAM2,SLIT2,KMT2C,EPS15L1,CLCN3,COG1,NMT2,CLTC,FAM189A2,ABCG2,C4orf33,SRP14-AS1,ARMC8,HS3ST5,SLC35F1,FAM171B,ENTPD4,RBM39,GDA,ABCG1,ARHGEF10,OSBPL3,CSNK1G3,VCAN,CNTNAP2,DZIP3,CTNND2,CCDC144A,CYBB,GAPVD1,DCAF8,LIN54,MATR3,TOMM20,ELMSAN1,MYEF2,CNIH3,FBXL5,TMEM130,SMG7,DLG2,EXOG,MED12,NR1D2,ECM2,GOLT1B,EBF1,SNX29,EDNRB,FCF1,YAF2,PHF20L1,ABI2,RCAN2,DENND4A,ETV1,RCSD1,EYA1,CLVS1,RPS6KC1,ACSL4,TAOK3,DLC1,CEP78,KIAA1109,FGF1,FGF12,PRKAG2,SUCO,MEX3B,FLT1,PSD2,HVCN1,TPK1,ATP2C1,NRG3,FYB1,GABRA5,GABRB3,GABRG2,ZNF234,ERAP1,C15orf41,DISC1,SULT1C4,MMADHC,RND1,GLRB,TNRC6A,MSL3,GNAO1,GPD2,GPM6A,GPM6B,CECR2,PCLO,DIDO1,NR3C1,RNF165,GUCY1B1,HAS2,DDX19B,HLF,LRRC75A,ZNF546,RBPJ,METTL21A,OLFM3,KCNH2,KCNJ16,KLRC2,KLC1,LAMP2,PAXBP1,PIK3AP1,MATN3,MIA2,POC1B,AFDN,MMP16,ERICH3,LAYN,NEXMIF,ZC3H12B,NEUROD1,NF1,NOS1,CLEC9A,NRCAM,HCN1,NTRK3,GPR137C,PAK3,ETFRF1,PDE1A,CDK14,GDAP1L1,PIK3C2A,ANLN,PCDH18,PMP2,MAPKAP1,SCHIP1,PMS2,ING3,SPATA6,EPB41L4B,FAT3,NXPH1,POU3F2,PPARA,TATDN3,PPP2R5C,RANBP3L,EPDR1,MAPK9,CNTLN,BDNF-AS,PTHLH,STK32A,FAM120C,PID1,TMEM255A,ZNF493,OXR1,MSANTD2,RDX,SLC6A15,REV3L,FIGN,PBRM1,TMLHE,CARF,PCMTD2,CCDC102B,TCP11L1,LRRK2,WLS,SEMA6D,HOGA1,FNIP1,GALNT10,NLGN4Y,ITSN1,CPEB3,FUZ,CHD9,SLC1A3,RAB3GAP1,SLC12A2,SLC15A2,SPHKAP,SMARCE1,RCOR3,TTC17,RIMS1,MBD5,CMTR2,SNRPN,PALLD,MYO16,UNC80,MYT1L,SP2,KDM4C,TAB2,SST,STAU1,AJAP1,TMEM150C,SYPL1,TACC1,ANKRD12,DDHD2,EXOC7,CAMSAP2,ALG1,ANO4,TBX15,EHBP1,SYNE1,DOCK9,SLC19A3,PCDHB4,SLC35G2,PCDHA1,CCDC173,FAM200B,PMS2CL,ZFPM2,AKTIP,TJP1,C5orf64,NPL,TPM3,TPM4,PDSS1,RUNDC3B,AMACR,ANO5,LRTM2,CLHC1,SGK3,TUBB1,RPL7L1,BCL2L13,RBFOX3,WIPF1,P2RY12,NSD2,CLDND1,ZIC2,KCNT2,TRIM9,ZNF195,SYNC,WNK1,PRDM10,RNF103,SNX27,WNK3,C12orf4,RGS7BP,KAT6A,PHTF2,RNF170,NHSL1,NETO2" MicroRNA hsa-miR-130a-3p:TargetScan hsa-miR-130a-3p TargetScan 1.29E-118 7.27E-115 1.15E-117 1.06E-116 231 721 "NCKAP5,NDRG2,ADARB2,ADCY2,CCDC85A,KIAA1211,GPR158,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,PPFIA2,MIER1,CAPRIN2,NCOA1,INSYN2B,ATP2B2,MTMR9,NOL4,FUBP1,NIPA1,LDLRAD4,CALB1,KALRN,PTBP2,CANX,CAST,MAP7,RUNX1T1,FMNL3,CFL2,KMT2C,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,BTF3L4,COL9A3,ACBD5,HS3ST5,SEC31B,CLOCK,CREB5,GDA,CSF1,LRIG1,IPCEF1,CHD5,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,CTIF,DNAL1,CEP170,KLHL3,G3BP2,FAM107B,DLG2,DNM2,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,EPB41L1,ENPP6,RAB9B,ERBB4,F3,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,NPTN,FUT9,MPP6,FYN,SALL3,NCKAP1,IQGAP2,GAP43,FAXC,GBX2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,RAPGEF4,GRB10,GRIK2,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,KCNA4,CDH20,KCNB1,KCNJ10,KCNN3,KIF5C,KIT,ARHGAP12,MAP4,MARK3,MBNL1,CHIC1,MDM4,LRP1B,AFF1,MYT1,NAP1L3,NEUROD1,NFIA,NOVA2,NPTX1,KCNK10,PAX6,PDE3B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,FAT3,POU3F2,POU6F1,PPP2R5E,PRKACB,PROX1,PSD,MDGA2,MTMR10,PXK,PTPRD,PTPRG,RAB5B,ATG16L1,RASGRF2,RBBP8,RDX,FIGN,RPRD1A,KLHDC8A,ROBO1,ROBO2,RORB,PRR5L,CLIP1,RTN1,RXRA,SATB1,ATXN1,ATXN2,FAM19A1,PPP1R9A,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,MYT1L,ERC1,CDK19,DIP2A,AJAP1,NUDT10,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMSAP2,FBXW11,SATB2,ARHGEF12,DICER1,HHIP,NACC2,R3HDM1,CSMD1,RBFOX2,FAM155A,REEP1,FSTL5,PMEPA1,MAP3K12,CADM2,LRP8,NAV2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-301a-3p:TargetScan hsa-miR-301a-3p TargetScan 1.29E-118 7.27E-115 1.15E-117 1.06E-116 231 721 "NCKAP5,NDRG2,ADARB2,ADCY2,CCDC85A,KIAA1211,GPR158,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,PPFIA2,MIER1,CAPRIN2,NCOA1,INSYN2B,ATP2B2,MTMR9,NOL4,FUBP1,NIPA1,LDLRAD4,CALB1,KALRN,PTBP2,CANX,CAST,MAP7,RUNX1T1,FMNL3,CFL2,KMT2C,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,BTF3L4,COL9A3,ACBD5,HS3ST5,SEC31B,CLOCK,CREB5,GDA,CSF1,LRIG1,IPCEF1,CHD5,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,CTIF,DNAL1,CEP170,KLHL3,G3BP2,FAM107B,DLG2,DNM2,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,EPB41L1,ENPP6,RAB9B,ERBB4,F3,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,NPTN,FUT9,MPP6,FYN,SALL3,NCKAP1,IQGAP2,GAP43,FAXC,GBX2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,RAPGEF4,GRB10,GRIK2,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,KCNA4,CDH20,KCNB1,KCNJ10,KCNN3,KIF5C,KIT,ARHGAP12,MAP4,MARK3,MBNL1,CHIC1,MDM4,LRP1B,AFF1,MYT1,NAP1L3,NEUROD1,NFIA,NOVA2,NPTX1,KCNK10,PAX6,PDE3B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,FAT3,POU3F2,POU6F1,PPP2R5E,PRKACB,PROX1,PSD,MDGA2,MTMR10,PXK,PTPRD,PTPRG,RAB5B,ATG16L1,RASGRF2,RBBP8,RDX,FIGN,RPRD1A,KLHDC8A,ROBO1,ROBO2,RORB,PRR5L,CLIP1,RTN1,RXRA,SATB1,ATXN1,ATXN2,FAM19A1,PPP1R9A,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,MYT1L,ERC1,CDK19,DIP2A,AJAP1,NUDT10,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMSAP2,FBXW11,SATB2,ARHGEF12,DICER1,HHIP,NACC2,R3HDM1,CSMD1,RBFOX2,FAM155A,REEP1,FSTL5,PMEPA1,MAP3K12,CADM2,LRP8,NAV2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-454-3p:TargetScan hsa-miR-454-3p TargetScan 1.29E-118 7.27E-115 1.15E-117 1.06E-116 231 721 "NCKAP5,NDRG2,ADARB2,ADCY2,CCDC85A,KIAA1211,GPR158,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,PPFIA2,MIER1,CAPRIN2,NCOA1,INSYN2B,ATP2B2,MTMR9,NOL4,FUBP1,NIPA1,LDLRAD4,CALB1,KALRN,PTBP2,CANX,CAST,MAP7,RUNX1T1,FMNL3,CFL2,KMT2C,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,BTF3L4,COL9A3,ACBD5,HS3ST5,SEC31B,CLOCK,CREB5,GDA,CSF1,LRIG1,IPCEF1,CHD5,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,CTIF,DNAL1,CEP170,KLHL3,G3BP2,FAM107B,DLG2,DNM2,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,EPB41L1,ENPP6,RAB9B,ERBB4,F3,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,NPTN,FUT9,MPP6,FYN,SALL3,NCKAP1,IQGAP2,GAP43,FAXC,GBX2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,RAPGEF4,GRB10,GRIK2,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,KCNA4,CDH20,KCNB1,KCNJ10,KCNN3,KIF5C,KIT,ARHGAP12,MAP4,MARK3,MBNL1,CHIC1,MDM4,LRP1B,AFF1,MYT1,NAP1L3,NEUROD1,NFIA,NOVA2,NPTX1,KCNK10,PAX6,PDE3B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,FAT3,POU3F2,POU6F1,PPP2R5E,PRKACB,PROX1,PSD,MDGA2,MTMR10,PXK,PTPRD,PTPRG,RAB5B,ATG16L1,RASGRF2,RBBP8,RDX,FIGN,RPRD1A,KLHDC8A,ROBO1,ROBO2,RORB,PRR5L,CLIP1,RTN1,RXRA,SATB1,ATXN1,ATXN2,FAM19A1,PPP1R9A,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,MYT1L,ERC1,CDK19,DIP2A,AJAP1,NUDT10,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMSAP2,FBXW11,SATB2,ARHGEF12,DICER1,HHIP,NACC2,R3HDM1,CSMD1,RBFOX2,FAM155A,REEP1,FSTL5,PMEPA1,MAP3K12,CADM2,LRP8,NAV2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-130b-3p:TargetScan hsa-miR-130b-3p TargetScan 1.29E-118 7.27E-115 1.15E-117 1.06E-116 231 721 "NCKAP5,NDRG2,ADARB2,ADCY2,CCDC85A,KIAA1211,GPR158,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,PPFIA2,MIER1,CAPRIN2,NCOA1,INSYN2B,ATP2B2,MTMR9,NOL4,FUBP1,NIPA1,LDLRAD4,CALB1,KALRN,PTBP2,CANX,CAST,MAP7,RUNX1T1,FMNL3,CFL2,KMT2C,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,BTF3L4,COL9A3,ACBD5,HS3ST5,SEC31B,CLOCK,CREB5,GDA,CSF1,LRIG1,IPCEF1,CHD5,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,CTIF,DNAL1,CEP170,KLHL3,G3BP2,FAM107B,DLG2,DNM2,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,EPB41L1,ENPP6,RAB9B,ERBB4,F3,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,NPTN,FUT9,MPP6,FYN,SALL3,NCKAP1,IQGAP2,GAP43,FAXC,GBX2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,RAPGEF4,GRB10,GRIK2,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,KCNA4,CDH20,KCNB1,KCNJ10,KCNN3,KIF5C,KIT,ARHGAP12,MAP4,MARK3,MBNL1,CHIC1,MDM4,LRP1B,AFF1,MYT1,NAP1L3,NEUROD1,NFIA,NOVA2,NPTX1,KCNK10,PAX6,PDE3B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,FAT3,POU3F2,POU6F1,PPP2R5E,PRKACB,PROX1,PSD,MDGA2,MTMR10,PXK,PTPRD,PTPRG,RAB5B,ATG16L1,RASGRF2,RBBP8,RDX,FIGN,RPRD1A,KLHDC8A,ROBO1,ROBO2,RORB,PRR5L,CLIP1,RTN1,RXRA,SATB1,ATXN1,ATXN2,FAM19A1,PPP1R9A,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,MYT1L,ERC1,CDK19,DIP2A,AJAP1,NUDT10,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMSAP2,FBXW11,SATB2,ARHGEF12,DICER1,HHIP,NACC2,R3HDM1,CSMD1,RBFOX2,FAM155A,REEP1,FSTL5,PMEPA1,MAP3K12,CADM2,LRP8,NAV2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-301b-3p:TargetScan hsa-miR-301b-3p TargetScan 1.29E-118 7.27E-115 1.15E-117 1.06E-116 231 721 "NCKAP5,NDRG2,ADARB2,ADCY2,CCDC85A,KIAA1211,GPR158,HECW2,OSBPL6,PITPNM2,AMPD3,LRCH2,PHF12,PPFIA2,MIER1,CAPRIN2,NCOA1,INSYN2B,ATP2B2,MTMR9,NOL4,FUBP1,NIPA1,LDLRAD4,CALB1,KALRN,PTBP2,CANX,CAST,MAP7,RUNX1T1,FMNL3,CFL2,KMT2C,PLAA,CLCN3,CLTC,QKI,HECTD1,MAP4K4,CNR1,PCYT1B,BTF3L4,COL9A3,ACBD5,HS3ST5,SEC31B,CLOCK,CREB5,GDA,CSF1,LRIG1,IPCEF1,CHD5,APPL1,PHF14,ARHGEF4,PPP6R2,CCDC144A,GAPVD1,ARHGAP24,DCAF8,RASSF2,LONRF1,MAML1,CTIF,DNAL1,CEP170,KLHL3,G3BP2,FAM107B,DLG2,DNM2,CPEB2,DPYSL2,GOLT1B,EDN1,HIPK3,FSD1L,FAM13A,EGR3,PAN3,EMX2,EPB41L1,ENPP6,RAB9B,ERBB4,F3,ACSL4,SCML2,DLC1,MED12L,SCARA3,FOXF2,ANKFY1,NPTN,FUT9,MPP6,FYN,SALL3,NCKAP1,IQGAP2,GAP43,FAXC,GBX2,ARFIP1,PPARGC1A,RAB30,FERMT2,GPT2,PRUNE2,RAPGEF4,GRB10,GRIK2,RNF165,KAT7,FICD,FAM222A,BACH2,MIER3,HLF,AGFG1,IGF1,IL6ST,ITPKB,KCNA4,CDH20,KCNB1,KCNJ10,KCNN3,KIF5C,KIT,ARHGAP12,MAP4,MARK3,MBNL1,CHIC1,MDM4,LRP1B,AFF1,MYT1,NAP1L3,NEUROD1,NFIA,NOVA2,NPTX1,KCNK10,PAX6,PDE3B,PDE4D,PDGFRA,PFKFB3,PIK3C2A,CCSER2,FAM216A,PURG,LRP12,FAT3,POU3F2,POU6F1,PPP2R5E,PRKACB,PROX1,PSD,MDGA2,MTMR10,PXK,PTPRD,PTPRG,RAB5B,ATG16L1,RASGRF2,RBBP8,RDX,FIGN,RPRD1A,KLHDC8A,ROBO1,ROBO2,RORB,PRR5L,CLIP1,RTN1,RXRA,SATB1,ATXN1,ATXN2,FAM19A1,PPP1R9A,ARX,CPEB3,CHD9,BTBD3,CCDC88A,BTBD7,CPEB4,EPC1,KIF13A,MYT1L,ERC1,CDK19,DIP2A,AJAP1,NUDT10,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMSAP2,FBXW11,SATB2,ARHGEF12,DICER1,HHIP,NACC2,R3HDM1,CSMD1,RBFOX2,FAM155A,REEP1,FSTL5,PMEPA1,MAP3K12,CADM2,LRP8,NAV2,FZD3,NHSL1,FXR1,FRMD6,GAN" MicroRNA hsa-miR-3134:mirSVR_lowEffct hsa-miR-3134:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-118 7.33E-115 1.16E-117 1.07E-116 311 1323 "TTYH1,ACTN1,TMEM132B,GALNT16,RNF157,GRAMD1B,ESYT2,KIDINS220,OSBPL6,SMIM17,SRPX,KIF6,CCDC146,PHF12,APC,APLP1,ALS2,VAT1L,BCAS1,CDC14B,MIER1,SLC7A14,LINC00173,MARK4,ASPH,NUMB,TMEM108,ATP1A1,STX16,ATP2A2,ATP2B2,ALDH7A1,B3GALT2,ATP6V0A1,ADGRB3,BCL2L2,DST,SCAPER,CASTOR3,C5,CACNB4,SLC25A14,NEURL1,SEPT7,CDC42,CDH8,CDH10,LGI1,LARGE1,DLGAP1,CHN1,NRXN3,IGFBP7-AS1,CLCN4,TMEM59L,IQCK,COL9A2,MYRIP,CLOCK,SLC32A1,ANKRD44,NCOR2,GDA,RGS6,SEC24C,ATRNL1,VAC14-AS1,SLITRK5,ERC2,CFAP61,CTNND2,CCDC144A,HDAC9,GAPVD1,PHF19,TBC1D5,KIAA0586,IP6K1,ELMSAN1,C8orf34,ZEB2,HEPH,MYEF2,MFAP3L,COPS7A,TMEM130,SV2B,SRGAP3,MTX3,DLG3,DNAH9,DOCK2,DPH1,CASP8AP2,ATN1,SGK2,MBNL2,KMT5B,TMEM132E,EIF4G2,ELN,CALCRL,KCNMB2,GPHN,MRVI1,WAC,TMEM132C,TUBA1B,TAOK3,SCML2,RACK1,CEP78,MED12L,KIAA1109,CAP2,IP6K2,PCYOX1,SLC37A3,MEGF10,HRASLS5,GALNT15,GABRG1,AHCYL1,DISC1,IGSF5,ALDH1L1,GCNT2,ADAM28,USP19,HEPN1,SPIN1,GLRB,TOX3,HTATSF1,PCLO,RAPGEF1,GRIA1,KIF3A,LINC00839,FAM19A2,ADAMTS6,IGSF21,PADI2,NXPH2,FRMD3,HLF,HPSE2,HMGCL,OPALIN,HTR2A,IRF8,IGF1,C5orf24,ZNF385B,ITGAM,KCNA6,KCNJ5,KIF2A,KLC1,PAXBP1,MARK1,MBD1,MBNL1,SYT9,MDFI,CHIC1,MEIS1,MOBP,MPP2,ERICH3,ZNF680,CTNNA3,MXI1,MYO6,NFIX,NHLH1,CNOT4,NOVA1,LRIT2,NTRK3,TBC1D25,OPA1,ZDHHC22,PDE1B,PIRT,PDGFRA,OLA1,PIK3R1,ZNF655,CCSER2,GPSM2,HMGCLL1,PURG,PDZRN4,PMP2,SDK2,SPATA6,MED1,PPP2R2C,PPP3CB,PKIA,HYDIN,VPS13C,SIDT1,WDR25,PTPRD,PTPRO,FAM120C,TMEM255A,USP47,SH3TC2,RAP1GDS1,ZNF493,DBX2,RADX,ZMAT4,TRIM68,REV3L,RFX4,RGR,CCDC82,C12orf49,PNMA8A,ROBO1,MRAP2,NEK11,SGSM1,LRRK2,ATAT1,STX1B,ZNF331,FOXRED2,CASC3,FOXRED1,TRA2B,COPZ1,ZFP30,NTNG1,FBXO11,FNDC3A,RPH3A,SLC12A2,SLC12A4,TMEM132D,ATF7IP,GKAP1,RIMS1,DOP1A,SOX2,EMC1,UNC5B,SRPK2,POGZ,LARP4,NEK4,SEPT8,RGL1,KLHL7,JMJD6,C3orf70,SYN2,ANKRD28,TACR1,KAZN,MTCL1,UNC5D,ADGRL3,VWA3A,VWC2,ZEB1,RPGRIP1L,PCDHB9,PCDHB7,ARHGEF12,FRYL,AP4E1,GPR161,HHIP,TIAM1,HEY1,DDHD1,BEX4,TNS1,NPL,DOK6,TSC1,AMOT,DNAJC12,SLAIN1,WIPF1,LAT2,SLC13A3,ZIC2,ZIC3,ZNF19,MICU3,LYPD6,ZNF142,SPIRE1,SMARCAD1,PARP6,SNX27,SLC17A6,PARP11,FAM13C,KAT6A,NLRP3,SOCS4,ST8SIA2,CPNE4,FAM198A" MicroRNA hsa-miR-3136:mirSVR_highEffct hsa-miR-3136:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.75E-118 9.82E-115 1.55E-117 1.43E-116 301 1242 "KCNH8,CLK4,ABHD6,TKTL1,XKR4,ADAR,CCDC85A,AXIN2,SORCS1,ADORA3,PTCHD1,BEND6,WDR35,ABCD2,MARCH4,PCDH10,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,PKP4,TNRC6C,LINC00173,STK33,ZBTB10,CHRD,NCOA1,NUMB,ATP1B3,ZNF582,SLC2A11,N4BP2L1,DST,MTMR2,JAZF1,C5,OSGIN2,CACNA1D,CACNB2,CALB1,PRC1,CCNH,MTMR7,SLC16A4,AIFM1,CDC42,LRRFIP1,TIGD7,CFL2,SOCS6,CHM,KMT2C,CLTA,ABCG2,FAM19A5,QKI,NIPBL,CNR1,FAM149A,AKAP6,ABI3BP,CPS1,FAM171B,CLIP3,ARHGEF10,ATRNL1,VCAN,SOCS5,PHACTR3,DZIP3,UBXN2A,CTNND1,RIMS2,RUBCN,HDAC9,RIPOR2,FRMPD4,TOX,DGKB,DCC,YTHDC1,DDX46,G3BP2,DLG2,GRIN3A,DMD,ABI1,DSCAM,DTNA,DNAJB6,E2F5,E2F6,EBF1,KLHL5,YAF2,PHF20L1,EGFR,MBNL2,GOLGA7,KCTD3,EIF4G2,ELAVL2,MRNIP,EIF1,RCAN2,RAB9B,F5,FAM198B,FABP7,SCML2,CHST15,KIAA1109,FGF1,CAP2,FLT1,STAU2,MSANTD4,OGA,DKK3,ERAP1,TUBGCP4,PCDH17,PPARGC1A,KIRREL3,PCDH11X,ZNF638,DCLK2,ZNF782,ADGRA3,EML4,CECR2,RAPGEF4,DIDO1,GRIA4,SERP2,GRM1,GYG1,TNFAIP8L3,NEGR1,SHISA6,SMAP1,IDH3A,C5orf24,USP54,IL6ST,BRINP3,INPP5B,ITGAM,KCND1,KCNJ16,KCNMA1,STXBP5,STMN1,HECTD2,NCOA7,LSS,MARK1,MAT2A,MBNL1,MDM4,COL28A1,MSR1,NCAM1,NFE2L2,NOS1,NRCAM,HCN1,OCRL,GPR88,OGG1,OXTR,PAK3,PCDH9,PRTG,PDYN,GNG2,BEST3,ABCB1,ZNF655,PLCL1,PLP1,HMGCLL1,NXPH1,PPP2R5C,PPP2R5E,RANBP3L,PKN2,MAPK4,MDGA2,CNTLN,PTPRB,ACSM5,CEP97,USP47,HKR1,ERI2,FIGN,RGS7,RLBP1,CCDC82,ALG9,CARF,CCDC102B,NEK11,LGR4,ABCA11P,ATAT1,RYR3,AMER2,ATXN2,ATXN7,SCN2A,SCN8A,ITSN1,SH3GL2,SHC4,HKDC1,CHD9,ANKRD6,WDR37,ABLIM3,FAM81A,PEX26,PPP4R3A,RUFY2,KANSL3,LRRC55,ELMO2,BTBD7,GKAP1,MAST1,SMARCE1,LIMCH1,RIMS1,ZNF415,SNRPN,SCN3B,PDZD2,SOX1,SP4,CDK19,TAB2,PBLD,STOX1,NKAIN2,STXBP1,AJAP1,KLHL7,PRRC2C,ARHGEF9,TAC1,PJA1,MCF2L,VWC2,TCF4,ZFP90,TRIM2,WASHC4,CLASP1,SYNE1,PCDHA5,FRYL,CRB1,TGFBR3,GZF1,MTMR14,TMPO,KAT6B,NPL,TPM3,RGMB,STXBP4,SSBP2,TUBB1,CADM1,FAM155A,PLEKHH2,USP1,BCL2L13,VLDLR,CLDND1,GUSBP1,SF1,ZNF711,ZNF28,LYPD6,ZBTB38,REEP1,FSTL5,ZXDA,EMSY,CADM2,PRDM2,MDH1B,NAV3,SLC17A6,MVB12B,HRASLS,FZD3,RTN4,TIGD6,GAN" MicroRNA hsa-miR-23a:PITA hsa-miR-23a:PITA_TOP PITA 3.81E-118 2.14E-114 3.37E-117 3.10E-116 242 799 "ABHD6,SYS1,KLHL32,ADD3,NLGN4X,PCDH19,RTL9,OSBPL8,SRPX,ARHGAP20,MAP4K3,PKP4,APAF1,SHROOM2,MIER1,PPP4R4,MADD,TMEM263,NCOA1,SLC4A4,MTMR9,B3GALT2,NOL4,SYNJ1,JAZF1,NIPA1,FOXK1,KALRN,MAP7,RUNX1T1,CCK,REPS2,DCLK1,LARGE1,DLGAP2,CFL2,SOCS6,NRXN3,CLCN3,NRXN1,TJP2,QKI,MAP4K4,CNR1,ARMC8,COL4A5,AKAP5,RCHY1,ZNF521,IGDCC3,AKAP12,CS,TENM4,LRIG1,CSNK1G3,PLCXD3,ST18,USP6NL,TOX,PHF19,MAML1,SIRPA,DNAJC6,POM121,SRGAP3,G3BP2,WDR20,DLG2,DLX1,RAB39B,MED12,CPEB2,DNAJB6,DYRK1A,ABCC5,EGR3,KCTD3,TENM1,CALCRL,ERBB4,ETV1,EYA1,PTK2B,ZIC4,KIAA1109,SPSB4,SUCO,VTI1B,FOXO3,FUT9,PHYHIPL,MEGF10,CHL1,CAB39,NEK6,C15orf41,WASF3,DNER,GCNT2,ARFIP1,PPARGC1A,GLS,TOX3,TNRC6A,GPR22,NUDT21,ADAMTS6,HAS2,ZHX1,KLF12,BACH2,MIER3,HNF4G,NEGR1,ZIC5,IL6R,JAK1,KCNK3,IPO5,CYP27C1,INSYN2,GPR155,MAP4,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MIA2,KITLG,MITF,MKLN1,AFF1,AFDN,MPP2,MSI1,HS6ST3,ZC3H12B,NEFH,NRGN,GPR88,PRTG,PDE4B,PDPK1,GNG2,OLA1,PIK3C2A,ZNF655,PPP2R5E,PKIA,CNNM2,ELOVL2,RBBP6,PRIMA1,PBRM1,ZFHX4,CCDC82,ROBO2,SNX22,RIMKLA,LGR4,SAFB,SEMA6D,SATB1,ATXN1,SCN2A,FNIP1,ZFP2,SEC14L1,NLGN4Y,SGK1,SCG5,KIF16B,MAGI3,AMBRA1,FBXO11,WDR37,SLC1A3,BTBD3,EPN2,RUFY2,SLC12A2,SPHKAP,CPEB4,PALLD,FAM126B,SOX11,HECW1,ZNF423,RBM26,SRPK2,POGZ,ZC4H2,NKAIN2,LRRC4,SS18,ERBIN,ELOVL4,SEPT3,SYT4,TAC1,CAMTA1,CAMSAP2,ANO4,ATMIN,SATB2,ZEB1,TRIM2,WASHC4,WDR7,RALYL,PSD3,PUM2,SIRT1,TGFBR3,NACC2,TJP1,TMOD1,TPM3,WBP2,TRPS1,FNDC5,SSBP2,CADM1,DNAJC12,TBC1D15,VSNL1,ZIC1,MICU3,REEP1,TMEM237,SMARCAD1,WNK1,EMSY,SLC38A1,PRDM10,SNX27,WIPF2,WNK3,SLC17A6,JMJD1C,SLC4A10" MicroRNA hsa-miR-23b:PITA hsa-miR-23b:PITA_TOP PITA 3.81E-118 2.14E-114 3.37E-117 3.10E-116 242 799 "ABHD6,SYS1,KLHL32,ADD3,NLGN4X,PCDH19,RTL9,OSBPL8,SRPX,ARHGAP20,MAP4K3,PKP4,APAF1,SHROOM2,MIER1,PPP4R4,MADD,TMEM263,NCOA1,SLC4A4,MTMR9,B3GALT2,NOL4,SYNJ1,JAZF1,NIPA1,FOXK1,KALRN,MAP7,RUNX1T1,CCK,REPS2,DCLK1,LARGE1,DLGAP2,CFL2,SOCS6,NRXN3,CLCN3,NRXN1,TJP2,QKI,MAP4K4,CNR1,ARMC8,COL4A5,AKAP5,RCHY1,ZNF521,IGDCC3,AKAP12,CS,TENM4,LRIG1,CSNK1G3,PLCXD3,ST18,USP6NL,TOX,PHF19,MAML1,SIRPA,DNAJC6,POM121,SRGAP3,G3BP2,WDR20,DLG2,DLX1,RAB39B,MED12,CPEB2,DNAJB6,DYRK1A,ABCC5,EGR3,KCTD3,TENM1,CALCRL,ERBB4,ETV1,EYA1,PTK2B,ZIC4,KIAA1109,SPSB4,SUCO,VTI1B,FOXO3,FUT9,PHYHIPL,MEGF10,CHL1,CAB39,NEK6,C15orf41,WASF3,DNER,GCNT2,ARFIP1,PPARGC1A,GLS,TOX3,TNRC6A,GPR22,NUDT21,ADAMTS6,HAS2,ZHX1,KLF12,BACH2,MIER3,HNF4G,NEGR1,ZIC5,IL6R,JAK1,KCNK3,IPO5,CYP27C1,INSYN2,GPR155,MAP4,MARK1,MAT2A,MEF2C,MEIS1,MEIS2,MIA2,KITLG,MITF,MKLN1,AFF1,AFDN,MPP2,MSI1,HS6ST3,ZC3H12B,NEFH,NRGN,GPR88,PRTG,PDE4B,PDPK1,GNG2,OLA1,PIK3C2A,ZNF655,PPP2R5E,PKIA,CNNM2,ELOVL2,RBBP6,PRIMA1,PBRM1,ZFHX4,CCDC82,ROBO2,SNX22,RIMKLA,LGR4,SAFB,SEMA6D,SATB1,ATXN1,SCN2A,FNIP1,ZFP2,SEC14L1,NLGN4Y,SGK1,SCG5,KIF16B,MAGI3,AMBRA1,FBXO11,WDR37,SLC1A3,BTBD3,EPN2,RUFY2,SLC12A2,SPHKAP,CPEB4,PALLD,FAM126B,SOX11,HECW1,ZNF423,RBM26,SRPK2,POGZ,ZC4H2,NKAIN2,LRRC4,SS18,ERBIN,ELOVL4,SEPT3,SYT4,TAC1,CAMTA1,CAMSAP2,ANO4,ATMIN,SATB2,ZEB1,TRIM2,WASHC4,WDR7,RALYL,PSD3,PUM2,SIRT1,TGFBR3,NACC2,TJP1,TMOD1,TPM3,WBP2,TRPS1,FNDC5,SSBP2,CADM1,DNAJC12,TBC1D15,VSNL1,ZIC1,MICU3,REEP1,TMEM237,SMARCAD1,WNK1,EMSY,SLC38A1,PRDM10,SNX27,WIPF2,WNK3,SLC17A6,JMJD1C,SLC4A10" MicroRNA hsa-miR-2861:mirSVR_lowEffct hsa-miR-2861:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.19E-118 2.35E-114 3.70E-117 3.41E-116 344 1613 "DGCR6,ABCF1,ASPHD1,EMILIN3,NCKAP5,KDM5D,FAM43B,CSMD2,GPRIN1,FMNL2,RNF157,BRAP,SLC12A5,GRAMD1B,UNC5A,PTCHD1,AP1B1,PCDH19,ALAD,SPOP,MRTFA,TRMT9B,KIF6,ZFAT,LRCH2,USP28,PPFIA4,CNIH2,APAF1,KCNAB2,APOC1,VAT1L,PPFIA3,SEMA4G,ASCL1,MARK4,CCDC74A,NCOA1,CCAR2,ALDH4A1,ATP1A3,N4BP2L1,TTLL9,ADAM15,ADGRB1,CDK5R1,LINC00906,OSGIN2,MYRF,BAIAP3,MMD2,CACNB2,KALRN,TRIM41,BRSK2,P2RX6,TMEM257,DCLK1,EVI5L,LGI1,CACNA2D2,FOXN3,CHGA,ASIC3,CHRM1,TAOK2,KMT2C,NRXN3,PPT2,QKI,AKAP7,FAM149A,COL11A2,ZNF521,CLIP3,CSF1R,SEC24C,MICAL2,CSNK1E,ATRNL1,PLCH2,VAC14-AS1,DZIP3,GREB1,FAM131B,CCDC144A,NOS1AP,TCAF1,SNPH,DCAF8,TOMM20,SCRN1,DBN1,ELMSAN1,B3GAT3,KIAA0753,KIAA0319,POM121,RHOBTB1,TMCC2,DNM1,NYAP1,RPS6KL1,SLC29A4,DOCK2,DUSP9,SIDT2,EFNB3,EGFR,RASA4,SORBS3,TENM1,BSCL2,DMTN,MTSS1L,SLC43A2,EPS8,NCALD,MRPL37,SRARP,ANKMY1,MRVI1,EZH1,REEP2,FAM198B,TUBB4A,CEP78,TOMM40L,STRADA,ZNF589,KIAA1109,HPCAL4,SYNCRIP,SLC37A3,ST6GALNAC3,PNMA2,TMEM151A,BRSK1,NEURL4,BRPF3,ZNF274,GCNT2,TUBA8,CSDC2,GGT5,ZNF276,RND1,TNRC6A,PCDH11X,LOXL3,ZNF782,WDFY3-AS2,GP1BB,LILRB4,CNTRL,ADAMTS13,NR3C1,GRM2,LINC01089,RNF165,AP4S1,SLC2A6,PADI2,NXPH2,DDX19B,AGBL5,HPCA,ZDHHC15,CPT1C,LINC00667,MYLK2,INPP5B,KCNJ11,LIMS1,VWA5A,PIK3AP1,ZNF667-AS1,LOC100128239,MAP6,MAPT,MATK,MDM4,MEIS1,KITLG,SCAMP5,MOBP,PTOV1,RSPO2,MYBPC1,FXYD6,NEUROD2,NNAT,NPTX2,NUMA1,OCRL,OPCML,GLIPR1L2,PALM,PBX1,PC,PDE2A,PFKFB2,PFKFB4,ZDHHC8,DUSP26,NLGN3,CAMKV,TMIE,PIK3CD,CCSER2,KCTD15,ST8SIA5,SLC25A23,PLXNB1,PLXNB3,C11orf49,SEPT4,TNPO2,FA2H,MAPK4,MASP1,VPS13C,SLC22A23,SIDT1,GDPD2,MDGA2,PSMD13,CNTLN,TMEM260,PTPRE,PEX2,NKAIN1,RAB3IL1,RAB5B,SLC25A48,USP47,IQSEC3,SLC25A41,RASGRF1,BSDC1,DPF2,ERI2,RGS12,KIF7,RNF220,CCDC82,CYB561D1,CCDC102B,SNX22,KIAA0895L,ATP8B4,STK32B,EMID1,SYNDIG1,MEG3,MAPK12,SBF1,DRAXIN,SCNN1D,PRCD,SCP2,HES6,ASIC4,TRIM46,ASRGL1,PPM1E,BCAN,ST3GAL3,CTXN2,BTBD3,SLC6A1,SLC6A9,YPEL4,SEPHS1,ARHGEF40,SLC12A4,ELMO2,SLCO1A2,SMARCC2,SORCS3,SNRPN,UNC80,FAM219A,WDTC1,SOX10,TEX2,LHPP,ZC4H2,NKAIN2,SSPO,MAPK8IP3,ZSCAN29,DIP2A,FGD4,ARC,ANKRD28,MTCL1,MLST8,DNMBP,CNTN2,SMG6,KLHL4,VWA3A,SIN3B,TPCN2,RPGRIP1L,AZIN2,SYNE1,NAT16,PHF24,FAM189A1,OBSL1,USP32P1,ARHGAP9,HIF3A,ATP13A2,CRB1,RELL2,HEY2,DAAM2,FAM124A,ANKRD24,TNFRSF1B,PRRT1,TPM2,ZNF346,TRO,FNDC5,UBE2H,OSBP2,RBFOX3,SF1,ZIC1,PLPP4,POLR3H,LMAN2L,SEMA3B,URM1,WNK2,FZD3,UBE3B,FAM219B,SSPN,PRRT4" MicroRNA hsa-miR-127-5p:mirSVR_highEffct hsa-miR-127-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.28E-118 2.40E-114 3.77E-117 3.48E-116 273 1025 "ACLY,RBM10,CSMD3,SLITRK1,ADD1,ADRB2,TAOK1,PCDH10,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,DGKZ,LGR5,CADPS,PDE8B,ASPH,ZBTB10,DDX3Y,STX16,ZNF583,N4BP2L1,CA8,CACNB4,CAMK2G,TRIM41,CANX,RGN,CDC27,LRRFIP1,TIGD7,CCPG1,CLGN,SRSF11,SYNPR,RAB33A,CNR1,ARMC8,BTF3L4,SLC4A8,HS3ST5,CP,CHD1L,FAM171B,CREM,MROH8,PITPNM3,PUM1,EDRF1,HDAC9,ARHGAP24,ARMCX4,YTHDC1,KIAA0753,COPS7A,MAGI2,BLOC1S6,DDX46,SACS,SV2B,KBTBD11,HS3ST2,CASP8AP2,DRD1,ACOT8,DNM1L,HIPK3,YAF2,FAM13A,GPR61,PHF20L1,ASB3,ELAVL2,DCTN4,VPS13B,ENPP6,DENND4A,TLR7,ADGRV1,SCML2,FCGR1A,BAIAP2,POLK,RGPD5,SGIP1,ZBED3,UFM1,OGA,MEGF10,GABRA2,ILDR2,AHCYL1,GALC,B4GALNT1,NEK6,LRRC37A6P,GDF9,SESN1,RAB30,TNRC6A,PCDH11X,ZNF638,LOXL3,PSRC1,MCHR1,PLCD4,NR3C1,GRM5,GUCY1B1,WIF1,LINC01102,C9orf129,ZDHHC15,LINC00667,KNDC1,LRRCC1,ZNF678,DIPK1A,INSM1,KCNJ3,KCNK2,KIF5C,KPNA5,PAXBP1,SYT9,SHC3,MEIS2,FXYD6,NCAM2,NEFM,NEK1,NELL2,NEUROD1,NF1,DNHD1,SLC11A2,HCN1,NUCB2,OMG,PAH,GLIPR1L2,PCSK1,PCSK5,PDE3B,BEST3,CYTL1,CAMKV,PIK3R1,SNX10,ZFYVE21,GPSM2,MINDY2,TATDN3,KANSL1,MAPK9,HYDIN,TMEM104,PTHLH,TMEM260,PTPRB,PTPRE,PTPRG,PTPRO,PID1,RAD17,ENOX1,OXR1,RASGRF2,GTDC1,RGS7,DCUN1D2,RAVER2,ATP8B4,ZNF354C,SEMA6D,SATB1,DRAXIN,ATXN7,LINC00461,SFPQ,SUPT20H,COPZ1,SH3BGR,ITSN1,FERMT1,CPEB3,DOCK10,FBXO11,FNDC3A,FHOD3,CNKSR2,NUBPL,PAAF1,DHX30,SPHKAP,SLN,MYH15,RCOR3,RIMS1,CMTR2,DOP1A,SP4,HECW1,SPP1,KDM4C,UNC5B,NPAS3,SPART,TAB2,POGZ,SST,SSTR2,ZSCAN29,SEPT8,CEP68,RGL1,DIP2A,ADHFE1,ACSBG1,FGD4,SYNE2,SYN2,ANKRD28,SYT4,TAC1,MTCL1,MCF2L,CAMSAP2,KIAA1107,EHBP1,TCF7,RPGRIP1L,WASHC4,CLASP1,SZT2,SYNE1,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,CCDC173,TEX15,SIK3,ZFPM2,TLL2,BHLHB9,ERCC6L2,TMPO,FAM124A,TNR,C9orf85,UBTF,FRRS1L,CLDND1,XRCC4,ZNF23,MKRN3,LYPD6,ZSCAN26,UPF3A,CADM2,STMN4,PCDH15,KCNAB1,EPM2A,RGS7BP,PHTF2,FBXO36,JMJD1C" MicroRNA hsa-miR-483-3p:mirSVR_lowEffct hsa-miR-483-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-118 2.70E-114 4.23E-117 3.90E-116 336 1543 "KCNH8,ABR,ADCY2,ADCY6,RNF157,AXIN2,SLC12A5,ADORA2A,OLMALINC,INTS2,KCTD16,OSBPL1A,CARNS1,ALK,AMPD2,KIF6,LRCH2,FGD2,ARMC12,SUGT1P4-STRA6LP-CCDC180,APBA2,APC,EPB41L5,MAGEE2,GPAM,VAT1L,AQP4,MIER1,MADD,RASL11B,ALDH4A1,ATP1A2,DOCK11,ADAM23,SNAI3-AS1,ADGRB3,DCAF5,KSR1,DST,LINC00906,WASF1,MYRF,MMD2,CA4,CACNA1E,CACNB2,CACNB4,CALB2,ZNF555,KALRN,PTBP2,TRIM41,CANX,CBLN1,CBS,USP6,P2RX6,ENTPD6,C1orf52,CDH8,ZNF445,MAGI1,RCBTB2,CHGA,B4GALT6,KMT2C,CPNE6,DNAJB5,MAP4K4,NIPBL,SLC4A7,SMARCAL1,HINFP,ANKRD44,CSF1,RGS6,MICAL2,SUSD5,PHACTR3,PLXNA4,DZIP3,KIAA0040,UBXN2A,CTNND1,RUBCN,NOS1AP,GAPVD1,RIPOR2,MAML1,SCRN1,IP6K1,ZEB2,MFAP3L,BLOC1S6,DDX46,GRIN3A,HS3ST4,DMPK,NYAP1,FAM57B,DPP6,PDCD6IP,ARRDC4,DTNA,DTNB,ECM2,DNAJB6,ABCC9,FAM135B,SEMA3D,EFNB3,PHF20L1,MBNL2,KMT5B,EIF4G2,ING4,ELN,PAN3,RCAN2,LRRC23,MTSS1L,KCNMB2,RTN3,RRAGB,MRVI1,ZIC4,DLC1,RACK1,FCGRT,FDFT1,TESK2,ZNF589,FGF12,FGFR1,TMEM164,SUCO,SCARA3,CAP2,NOP56,SMC2,ARFGAP2,CAMKK2,ATP2C1,ERGIC3,STAU2,DOT1L,MEGF11,DKK3,HRASLS5,GALC,GAP43,SIGLEC8,DISC1,SEPT9,INPP5K,LRRC37A6P,ALDH1L1,GFER,GHR,SPIN1,GLS,KDM2B,RAB40B,GNAS,STON1,NUDT21,PLCD4,BTN2A1,LINC00839,GSTM5,RNFT2,ATOH8,TMEM179,ARHGAP19,NCKAP1L,HMGCL,HP,HPR,HSF2,FAM95B1,SHISAL1,IGF1,TJAP1,BRINP3,ZNF678,ITPKB,KCNJ16,KCNK2,KCNMA1,STXBP5,L1CAM,CAMK2N2,PAXBP1,PACRG,LOC100128239,MBP,MDM4,PPM1L,MITF,AFF1,AFDN,SAMD5,MTR,NCF2,NOS1,SLC11A2,NUMA1,OPA1,CLDN11,SNTG1,PAK3,CNTN3,BEST3,CDK14,CAMKV,ZFYVE21,SDK2,RETREG2,PTPA,PPP2R5E,PPP5C,HYDIN,SNRK,WDR25,PIGG,OCIAD1,PTPRG,PEX5,RAB5B,TMEM255A,FAM66C,ATG16L1,ROGDI,GAL3ST4,SLC6A15,TRIM68,RFX2,ARHGEF10L,SEC61A2,RIC8B,RNH1,MYH14,TMLHE,EXD2,ARMC5,GSTCD,CCDC102B,MRAP2,EPHA10,UEVLD,ATP8B4,ACER3,ABCA11P,FNIP1,COPZ1,ST6GAL1,DZIP1,SLA,FAM81A,PREX2,DHX30,KANSL3,PKNOX2,YPEL4,RAB3GAP1,SLC8A3,CCDC88A,SLC12A2,ZNF334,NAPB,BTBD7,SLCO1A2,ZFP1,SMARCD3,SNRPN,SCN3B,SON,TRERF1,ZSWIM8,KDM4C,UNC5B,KIF1B,IQSEC2,TSPYL2,MCF2L2,NFASC,COLGALT2,SS18,SSPO,STAU1,ELOVL4,SULF2,DNAJC9,SYP,SYPL1,SLC37A2,TACC1,ROBO3,SATB2,SYNE1,SLC19A3,USP32P1,AHCYL2,DICER1-AS1,TIAM1,TLR4,ZFP91,RIMBP2,KCTD2,TNS1,NPL,TPM2,ZNF346,RUNDC3B,KCNE5,ANO5,ZKSCAN5,HEPACAM,PLPPR2,TBC1D15,CFAP298,TRIM9,FMN2,CRB2,CELF4,ZBTB38,ZBTB16,FTSJ1,UPF3A,DHX33,WNK1,CSDE1,NAV2,CERS6,ACTR3B,SLC4A10" MicroRNA hsa-miR-373:mirSVR_highEffct hsa-miR-373:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.82E-118 2.71E-114 4.23E-117 3.90E-116 329 1482 "KIAA1211,PTCHD1,MTUS1,GPR158,AK2,SPOP,ALCAM,ABCD2,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,API5,APP,SHTN1,RGS20,STK33,ASPH,STX16,DPY19L3,BACH1,MPDZ,DCAF5,BID,CFLAR,DST,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CACNA1E,CALB2,AIFM1,SEPT7,ZBED1,LRRFIP1,MAGI1,CLGN,CFL2,CHN2,TAOK2,NRXN1,ABCG2,C4orf33,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,FAM171B,CRHBP,HAPLN1,ANKRD44,GDA,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,HDAC9,TOX,KIAA0586,DCTN1,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,RABGAP1L,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,ABCC9,GOLT1B,E2F5,E2F6,EDN3,EDNRB,ANKRD46,HIPK3,YAF2,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,DNAJC27,FABP7,CORO2B,MED12L,POLK,SUCO,NELFCD,TACC2,USP16,MSANTD4,FYB1,ZMYND11,ARPP21,IGSF5,TUBGCP4,ADAM28,GGTA1P,MALT1,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPM6A,GPR12,GPR34,CECR2,PCLO,GRIA1,RFFL,GRM5,TMEM25,FICD,UBE2QL1,HPS5,C1orf94,ARHGAP36,ZDHHC15,HSP90AA1,SMAP1,MSL1,C5orf24,ITGAV,JAK1,OLFM3,KCNMA1,KCNN2,CYP27C1,LAMP2,SYTL4,HECTD2,NCOA7,PIK3AP1,ZNF667-AS1,MARK1,SYT9,MDM4,SRSF12,KITLG,PPM1L,POC1B,ADAM22,RSPO2,MYCN,MYO9A,NACA,NCF2,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPA1,OPHN1,PCDH9,PCSK2,PDCD2,BEST3,PFKFB2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,ANKRD16,TRHDE,PRRX1,SPATA6,DRAM2,PPP3CB,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,PTPRD,PTPRG,CEP97,TMEM255A,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,ZYG11B,TRIM68,GTDC1,FIGN,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SCN3A,IL17RB,SHC4,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ENKUR,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,RGL1,SULF2,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,SYT1,CAMTA1,CAMSAP2,UNC5D,TBCEL,ZFP90,CUX2,TCF7L2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,NR2E1,TNS1,RGMB,PRMT8,TRPC1,PPIL6,FAM181B,PLEKHH2,ZNF709,CCDC14,VLDLR,XPO1,KCNT2,TRIM9,FMN2,LYPD6,LAMP5,SYNC,CADM2,PRTFDC1,RGMA,PRDM8,PRDM10,PCDH15,SLC17A6,NELFE,PLSCR4,DNAH10,FAM13C,MARCH8,PAK5,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-513b:mirSVR_highEffct hsa-miR-513b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.14E-118 4.01E-114 6.27E-117 5.77E-116 300 1240 "ACADM,TKTL1,KLHL32,CCDC85A,PTCHD1,AGT,CC2D2A,HFM1,ADGRF5,ALCAM,FAM135A,SYT13,AMPD3,LRCH2,PARG,LRRC4C,LGR5,AQP4,ARRB2,ASPH,CCDC181,ATP1B3,ATP6V1G2,BACH1,SNAI3-AS1,BBS2,DST,SYNJ1,ARHGEF7,SCAPER,WASF1,LURAP1,PTBP2,SPAG9,RUNX1T1,SLC16A4,TMEM257,C1orf52,LRBA,ZMYM4,CDO1,DLGAP1,CCPG1,CHN2,CASC2,SYNPR,LSMEM2,RAB33A,NRXN3,SLC24A2,TPP1,IQCK,COL9A1,TBPL1,AHCTF1,IGDCC3,HS3ST5,SLC35F1,CRMP1,ABCG1,ARHGEF10,CSNK1G3,ATRNL1,SOCS5,DZIP3,PHF14,RIMS2,FAM131B,BOC,DOCK4,HDAC9,GAPVD1,ARHGAP24,TOMM20,SIRPA,DCTN1,ZNF804A,C8orf34,ZEB2,COPS7A,DDX46,PLPPR4,FAM107B,KIF19,KBTBD11,DLX1,RPS6KL1,DPH1,DTNA,DNM1L,E2F6,FAM135B,CALCRL,EN2,RASGRP2,STX2,SRRM1,DENND4A,ADGRV1,WAC,SH3YL1,CACNG3,TAOK3,DLC1,GORAB,KIAA1109,FGF1,CAP2,VTI1B,ANKFY1,EFCAB2,SPECC1,UFM1,USP21,DACH2,PNMA2,TBR1,ZNF512,FYN,GABRB1,GAD1,GAD2,JPH4,SALL3,KIAA1841,MYOZ2,NEU3,ARFIP1,GHR,DBF4,GLYR1,RAB30,GLS,MSL3,GPD2,EML4,GRIA4,GRID1,NR3C1,GRM7,KAT7,MAEL,FRMD3,NEGR1,ICA1,IRF8,MSL1,ZNF678,INSM1,ITGAV,SLC35G1,KCNA2,KCNC2,KCNMA1,STXBP5,SFXN5,PAXBP1,PACRG,SMAD1,MARK1,MAT2A,SYT9,WDR49,BLOC1S2,DDX25,CTNNA3,MYCN,LAYN,NPTX1,OPHN1,P2RY1,GLIPR1L2,PCSK5,PRTG,PDE1A,PDE3B,PDE4D,GPR85,CDK14,PRIMPOL,PDZRN4,MAPKAP1,SCHIP1,EPB41L4B,PACSIN1,TNPO2,FA2H,MED1,PPP2R5E,PPP3CA,CEP41,SLC22A23,APTX,SIDT1,ELOVL2,TMEM260,CEP97,TMEM255A,FAM66C,ZNF493,RASGRF1,ARID4A,ZDHHC14,REV3L,SEC61A2,ZFHX4,TMLHE,RAVER2,GSTCD,ELP2,PCMTD2,LRRK2,CNTNAP3,DGLUCY,SLC30A10,ITSN1,MYO18A,PREX2,PPP4R3A,DHX30,RUFY2,KDM4D,SEPHS1,TET1,CPEB4,OGDHL,DMRTC1,TTC17,RIMS1,SNAP25,SNRPN,TMCC1,MYT1L,SOX2,SOX5,ZCCHC24,FNBP1,DOK5,KDM3A,MYCBP2,CDK19,C11orf87,CLSTN2,STAU1,ELOVL4,CEP68,RGL1,VPS13A,FNDC9,PLCB1,SYN2,SYT4,TACC1,ROBO3,CAMTA1,ADGRL3,TBCEL,TCF7L2,USP22,CLASP1,WDR7,SYNE1,FRYL,SIRT1,CRB1,C18orf54,AP4E1,ZFP91,KAT6B,SEZ6L,NPL,PRMT8,TSN,TTC3,ZKSCAN5,TMEFF2,CADM1,UBE3A,UCHL1,FLRT2,TBC1D15,P2RY12,NSD2,CLDND1,ZIC2,ZIC3,ZNF17,MICU3,GPR158-AS1,MKRN3,ZBTB38,FSTL5,SMARCAD1,EMSY,CADM2,ADAMTS9,NAV3,KAT6A,SLC4A10,SENP7" MicroRNA hsa-miR-500:mirSVR_highEffct hsa-miR-500:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.97E-118 4.48E-114 6.98E-117 6.43E-116 307 1298 "ACADM,CLK4,NCKAP5,CSMD2,CSMD3,GALNT13,PLEKHH1,BEND6,PCDH19,ABCD2,ARHGAP20,USP28,PPFIA1,EPB41L5,GPAM,ALS2,CACHD1,AMER3,MIER1,ZFYVE28,ARNTL,CADPS,MARK4,PCDHGB4,SLC4A4,ALDH7A1,RIPK1,BACH1,CFLAR,KSR1,SYNJ2,ARHGEF7,FUBP1,IL33,CA8,LURAP1,KALRN,PTBP2,MTMR7,C1orf52,DGKI,DCLK1,LGI1,COPB2,NDST3,KMT2C,IGLON5,IQCK,AKAP6,SLC4A7,SLC4A8,BAG4,MYRIP,CNRIP1,RNF14,CS,SIPA1L1,UBXN2A,RIMS2,EDRF1,HDAC9,RIPOR2,ZFYVE16,DCC,DNAJC6,C8orf34,ZEB2,MAGI2,BLOC1S6,DDX46,G3BP2,DLG2,DNM1,HS3ST2,DMTF1,CASP8AP2,ACOT8,PDCD6IP,DYRK1A,GOLT1B,E2F5,WDPCP,FCF1,SEMA3D,RBM12,ELAVL4,PCOLCE2,EYA1,FAM198B,DLC1,ST3GAL6,FGF12,PRKAG2,POLK,ATP13A4,FLT1,SGIP1,C2orf88,APOPT1,ATP6V1H,STAU2,ZMAT1,GABRB3,GABRG2,DENND2A,AHCYL1,ZNF274,MTHFD2,C15orf41,DISC1,KIAA1841,MSTN,MMADHC,MALT1,GLS,PCDH11X,KDM2B,GOLGB1,GPM6B,GPR12,RAPGEF4,GRIA1,GRIK1,NR3C1,GRM1,COQ10A,AP4S1,GUCY1A2,MAEL,HAS2,MIER3,HMGB1,HMGCR,IGFBPL1,USP51,SHISA6,ICA1,ZNF181,LRRTM3,SLC35G1,METTL21A,OLFM3,KCNH2,KCNJ16,KCNK1,MAP4,MARK1,MATN2,MBNL1,LRP1B,BLOC1S2,ZNF862,NAP1L1,NFE2L2,NINJ2,HCN1,NUCB2,OPA1,PCDHGC3,PDE3A,PDE4D,GPR85,NALCN,CCSER2,SNX10,XRN1,SMOX,PURG,PRIMPOL,STRN3,ING3,NXPH1,PPP2R5E,PRKACB,PRKCZ,EPDR1,MAPK9,GRAMD1C,HYDIN,LRRC49,CNTLN,OCIAD1,TMEM145,PEX2,ZNF844,CEP97,FAM66C,OXR1,ARID4A,RDX,ZMAT4,ERI2,FIGN,RFX3,RFX4,RFX5,SLC25A36,RIC8B,EXD2,ROBO2,PCMTD2,TMEM100,BAALC,GLDN,ADAL,LRRK2,CNTNAP3,LGR4,FAM192A,SATB1,SCN3A,SCP2,SEC14L1,CASC3,TRA2B,SGK1,KIF21A,ASAP3,HKDC1,ST6GAL1,ANKRD6,PAAF1,SLC1A3,FAM81A,DHX30,SLC6A1,PKNOX2,ARHGEF40,ATF7IP,TET1,SORCS3,RCOR3,LIMCH1,SNAP25,SNCA,UNC80,TRERF1,BDP1,ZC3H13,C11orf87,COLGALT2,ZNF302,LARP4,ERBIN,SEPT8,TTBK2,ADHFE1,KLHL7,FGD4,VPS13A,C12orf76,TAC3,ANKRD12,DDHD2,TAF9,KLHL4,ANO4,TCEA1,EHBP1,SATB2,CUX2,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TEX15,SIK3,HEY1,TLR4,TP53BP2,C9orf85,RFTN2,FAM155A,UBE3A,TOM1L2,TBC1D15,RICTOR,GUSBP1,XPO1,ZIC2,KCNT2,GPR158-AS1,ZBTB38,REEP1,ZNF184,ZSCAN26,SPIRE1,SYNC,UPF3A,SLC30A4,EMSY,PRDM2,TMEM178A,SEMA3B,SMIM8,NUP214,JMJD1C" MicroRNA hsa-miR-617:mirSVR_lowEffct hsa-miR-617:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.05E-118 4.52E-114 7.04E-117 6.48E-116 325 1450 "TTYH1,ADCY6,SNX30,SORCS2,SRPX,PCDH10,FAM135A,PHF12,PPFIA2,KCNAB2,ALS2,TNRC6C,IGDCC4,PLA2G4C,CAPRIN2,SYNJ1,MYRF,CACNA1B,KALRN,PTBP2,VXN,MAP7,RUNX1T1,P2RX6,LRBA,CDC42,CDH8,LRRFIP1,LGI1,L3MBTL4,LARGE1,GPR37L1,SOCS6,CHN2,CHRM1,CLCN3,C4orf33,SRP14-AS1,ARHGEF6,CNR1,COL4A5,AKAP5,ABI3BP,TBPL1,C2CD2,CRMP1,NCOR1,ARHGEF10,CSNK1G3,SUSD5,USP6NL,FAM131B,CYBB,HDAC9,TCAF1,DCAF8,TBC1D5,PITPNC1,TIAM2,HP1BP3,GSDME,DDX46,MTX3,KIF19,DNM2,DOCK2,DMTF1,DPP6,PDCD6IP,ARRDC4,EDIL3,EDNRB,ANKRD46,HIPK3,CNNM1,KLHL5,GPR61,SUGP2,COPS4,EPHB1,TMEM74,RTN3,RASL12,TUBB3,POLK,UBE2E3,CAP2,SEMA6C,EVL,FLT1,UFM1,RASL10A,KHDRBS3,DACH2,DOT1L,STAG2,DKK3,ZMYND11,ZNF234,NEK6,ERAP1,DISC1,DNER,NEU3,USP19,GGT7,PPARGC1A,CRCP,MSL3,ZNF638,KDM2B,ADGRA3,LILRB4,PRUNE2,NUDT21,STMN2,GRB10,GRIA2,GRID1,GRIK1,FAM107A,SLC2A6,FAM222A,HAS2,PADI2,HLF,GABARAPL2,SYNPO,HMGCR,HNF4G,C9orf129,IRF8,IDH3B,C2orf72,IGF1,KNDC1,TJAP1,DISP2,SCIN,IL11RA,KCNB1,GPR62,KCNH1,KCNJ3,KCNJ9,KCNJ11,KIF5A,KIF5C,STXBP5,KTN1,STMN1,LIMS1,HECTD2,SMAD1,LDLRAD3,LRP1B,MEIS1,KCTD6,MID1,MITF,XRRA1,MOBP,COL28A1,NRBP2,MYBPC1,LYRM9,MYO5A,HNRNPM,NAP1L2,NBL1,CNOT4,SMIM11A,OCRL,ODF2,PCDH8,PCSK5,PDE4A,PDE4B,GNG2,CDK14,SEMA5B,PIK3R1,KCTD15,PLCB2,ANKRD16,LRP12,EPB41L4B,SLC36A4,PACSIN1,POU6F1,TMEM235,MED1,PPM1B,CCDC144B,CRLS1,PPP2R5C,PPP3CB,NKAIN4,PRKCB,PKN2,MAPK4,EPDR1,NDUFS7,WBP1L,MDGA2,CNTLN,ANKHD1,PLPPR1,PTN,TMEM260,PTPRB,ZNF493,ARID4A,RET,RGR,UBR7,RGS10,EXD2,KLHDC8A,ALG9,GSTCD,CYB561D1,STK32B,PAQR6,ABCA11P,NCBP3,SATB1,SBF1,ATXN2,SCN2A,LINC00461,HES6,ZNF821,SUPT20H,CHD9,CTXN2,ABLIM3,SLA,SLC1A7,PPP4R3A,EPN2,SMTN,RAB3GAP1,SLC20A2,CPEB4,GKAP1,SNCA,MBD5,TMCC1,PDZRN3,SCN3B,DOP1A,SON,WDTC1,SOX11,DOK5,SP4,NMNAT2,GLT8D1,KDM4C,CDK19,TSPYL2,SRPK2,ITPRID2,ZNF302,NKAIN2,RGL1,DIP2A,STX1A,AJAP1,GSE1,NSFL1C,SYT11,VAMP1,RHBDL3,PLCB1,SYN1,COBL,SYT4,SEMA4A,UNC5D,ADGRL3,ZFP90,TCF7L2,TPCN2,NAT16,TNS2,RNF216P1,DICER1,KHDC1,CHST8,FBXL16,TIAM1,TK2,HEY2,RIMBP2,TPM4,SYNPO2,TRO,TTTY15,LINC00689,USP1,VSNL1,RICTOR,AGMO,CRB2,FSTL5,INTS3,DNALI1,LRP8,SLC38A1,HPS4,URM1,WIPF2,FAM13C,DOCK8,PAK5,FBXO36,CASC15,NUP214,TIGD6,RNF170,NHSL1,SLC4A10,GAN" MicroRNA hsa-miR-19a*:mirSVR_highEffct hsa-miR-19a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.45E-118 5.31E-114 8.25E-117 7.60E-116 304 1274 "ARID1A,SORCS1,KIAA1211,DPY19L2P4,OLMALINC,PCDH19,KIAA1324,WDR35,CC2D2A,SEMA6A,SPOP,ANK3,USP28,GPAM,VAT1L,API5,APP,SHTN1,PPP4R4,SPTBN4,NUMB,EIF4G3,B3GALT2,BACH1,BCL7A,LINC00906,MTMR2,SGCE,OSGIN2,IL33,CACNA1B,CALM1,KALRN,PTBP2,CAMK2D,VSTM2A,CAST,CDH8,LRRFIP1,NOG,CFL2,CBARP,SOCS6,CHM,CASC2,JAM2,NRXN3,PPT2,CLCN4,NRXN1,FBXO7,FAM189A2,C4orf33,NIPBL,ARMC8,RCHY1,MYRIP,IGDCC3,MFSD4A,CP,SLC35F1,FAM171B,CLOCK,FEZ2,MICAL2,SUSD5,PLCH2,PLXNA4,PHF14,CTH,CTNND1,USP6NL,ARHGAP32,FRMPD4,KCTD8,DAPK1,SCRN1,PABPC5,BRINP1,AIF1L,ARMCX4,CEP170,RHOBTB1,AK5,FAM107B,DMD,CPEB2,DRD1,ABI1,DTNA,EDN1,EDNRB,RASGRP1,KLHL5,PHF20L1,EGFR,EIF4G2,ELAVL4,EMX2,LRRC17,CEP85L,CDKL3,RTN3,TLR7,CEND1,ADGRV1,CACNG2,TAOK3,DLC1,TOMM40L,FDFT1,POLK,CAP2,PCYOX1,FLT1,JKAMP,TMEM107,SMC2,FAM49B,NPTN,ATP2C1,CELF1,PHYHIPL,MEGF10,CHL1,GABRB3,CAB39,GAD2,HBS1L,MTHFD2,GATM,NEU3,ARFIP1,AHDC1,GLI2,GLRB,TOX3,ZNF638,GNAO1,FERMT2,GRB10,GRIK2,PTPN5,SOX21,RASSF8,FRMD3,ARHGAP36,NEGR1,SHISA6,LRRCC1,LIX1,KCND2,KCNK2,STXBP5,TTYH2,PAXBP1,VWA5A,ASPRV1,PIK3AP1,MARK1,MATN2,SYT9,EFHB,MEIS1,KCTD6,MIA2,PPM1L,MITF,MOG,ZNF680,MYO9A,NAP1L1,NAP1L2,NFE2L2,SMIM11A,OGG1,LOC100128398,CLDN11,P2RX7,PCSK5,PDE1C,SLC10A4,GNG2,FAM218A,CCSER2,RETREG1,PRIMPOL,LRP12,PSAT1,ING3,POU3F2,CCDC144B,PRKCB,MAPK10,HYDIN,SIDT1,ELOVL2,PTK2,PTN,STK32A,PTPRB,PTPRD,QDPR,TMEM255A,RASGRF2,UBR7,RIC8B,NUDT11,RNASEL,ROBO2,PCMTD2,RPE65,SPIN3,MCMBP,LRRK2,ABCA11P,HSD11B1L,RTN1,FAM182A,SATB1,ATXN7,SCN7A,SCN8A,FNIP1,KIF21A,SH3GL2,CPEB3,CTXN2,SLA,SLC6A8,ZNF430,TET1,RCOR3,ANKRD36,LIMCH1,PALLD,UNC80,SOX5,KDM3A,SP4,ZC3H13,ITPRID2,ZC4H2,NXT2,RGL1,SYT11,VPS13A,SYT1,C12orf76,ANKRD12,CAMTA1,FAM208A,ADGRL3,TCF4,ZEB1,TRIM2,SYNE1,PCDHB9,OBSL1,PUM2,GZF1,NR2E1,TMPO,R3HDM1,C9orf85,TPM4,SYNPO2,TRO,TRPC1,ANKRD20A2,TUB,PRR18,TMEFF2,TUBB1,RPL7L1,FAM155A,BCL2L13,P2RY12,NSD2,GUSBP1,XPO1,XRCC4,CFAP298,ZIC2,ZNF28,KCNT2,TCEAL7,ZNF138,ZNF154,REEP1,ANKS1B,SPIRE1,PLPPR5,CA10,PRDM2,CSDE1,TMEM178A,NAV3,PDSS2,FZD3,KLHDC1,DPF3,SLC4A10,JPH3" MicroRNA hsa-miR-1297:mirSVR_highEffct hsa-miR-1297:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.45E-118 5.31E-114 8.25E-117 7.60E-116 304 1274 "ACADM,CLK4,ACTN2,SORCS1,PLEKHH1,PWWP2A,SLC24A4,ZNF608,INTS2,HACE1,TXNDC16,SMIM17,ANK1,LRCH2,ANK2,EP400,APAF1,APC,TNRC6C,SHTN1,MIER1,TMEM263,RGS20,CDK13,CCDC74A,ATP1A2,SLC4A4,LINC00847,BID,GPR146,BMPR1B,DST,FUBP1,SCAPER,OSGIN2,WASF1,CACNB2,KALRN,MAP7,KRIT1,USP6,LGI1,SRSF11,SOCS6,CHN2,KMT2C,CLCN3,NRXN1,CLTC,TJP2,DNAJB5,TMEM184B,CNR1,AKAP7,COL4A5,SLC4A7,BAG4,ACBD5,C2CD2,HAPLN1,SNCAIP,PLXNA4,DZIP3,ERC2,GREB1,CTNND2,ST18,RUBCN,BOC,DOCK4,HDAC9,KATNAL2,HDAC4,DAPK1,PITPNC1,ARMCX2,JAKMIP2,ZEB2,HEPH,MFAP3L,C2CD2L,PLPPR4,SACS,G3BP2,WDR20,DLG2,EXOG,GRIN3A,DMD,USP3,PDCD6IP,TMTC1,FSD1L,RBM12,EIF4G2,EIF5,ELAVL2,CALCRL,PAN3,VPS13B,EPHA5,EPHB1,ETV1,FAM198B,RPS6KC1,TMEM132C,CEP78,GORAB,FGF14,CAMSAP1,MEX3B,SEMA6C,SEMA4D,SGIP1,UFM1,DACH2,GABRA2,ZNF44,FAM184B,ARPP21,GALR1,NEK6,DISC1,ACSS1,SRCAP,PPARGC1A,GK,GLS,TNRC6A,ZNF638,KCNMB4,GRB10,DIDO1,GRIA4,RFFL,GRM7,LINGO1,ADAMTS6,ZHX1,LINC01102,MIER3,HNF4G,CELF5,HTR2A,ZIC5,IL6ST,DIPK1A,TUBB2B,KCND2,KCNK1,SMAD1,MAP2,MARK1,MAT2A,MITF,AFDN,MMP16,MOG,CD200,ZNF680,BLOC1S2,ZNF92,MTTP,MXI1,CCDC13,NEK1,CNOT4,SLC11A2,NUMA1,PCDH9,PDE3B,SLC10A4,BEST3,PFKFB3,FAM98B,OLA1,SNX10,GPSM2,FAM216A,PLCL1,PLP1,PCDH18,HMGCLL1,PURG,PMP2,ING3,FA2H,MINDY2,PPM1B,PPP2R5C,PPP3CB,RANBP3L,CEP41,GRAMD1C,HYDIN,DIRAS2,VPS13C,PIGG,PXK,PTPN13,PTPRD,FAM120C,TTC13,ZNF615,PPP2R3C,RALGDS,ZCWPW1,VEPH1,SLC6A15,ZYG11B,UBR7,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,GSTCD,ARMH4,GLDN,CNTNAP3,LGR4,ABCA11P,RTN1,ZNF331,SALL1,SEMA6D,SATB1,FNIP1,GALNT10,SFPQ,MRAS,KIF27,CHD9,FBXO11,NLGN1,RUFY2,ZNF430,CCDC88A,SLCO1A2,TET1,SORCS3,MYH15,LIMCH1,PALLD,TMCC1,USP33,MYT1L,ZCCHC24,CAND2,ZC3H13,NPAS3,CLASP2,TROVE2,STOX1,EPB41L3,LARP4,STAC2,NECAB1,SYNE2,VAMP1,PLCB1,ANKRD28,SYT4,POPDC3,PJA1,DNMBP,FAM208A,KLHL4,TCEA1,RALYL,USP32P1,FRYL,C18orf54,AP4E1,ERCC6L2,FAM124A,C5orf64,AMACR,STXBP4,TRPC3,PPIL6,DCBLD1,ANKRD20A2,TTC3,TTPA,AMOT,PLEKHH2,BCL2L13,VLDLR,TBC1D15,CLDND1,ZNF708,MKRN3,ZBTB38,ANKS1B,WNK1,EMSY,MDH1B,MPPE1,WNK3,PDSS2,PHTF2,RNF170,VANGL2" MicroRNA hsa-miR-619:mirSVR_lowEffct hsa-miR-619:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-117 9.19E-114 1.42E-116 1.31E-115 351 1683 "CPNE2,RALGAPA1,ABR,ACADM,ARID1A,TMCC3,PNMA8B,USP31,SNX30,SLC24A4,MTUS1,DISP3,AK2,C1QTNF3,SPARCL1,SEMA6A,CARNS1,FAM135A,PITPNM2,CCDC146,PPFIA1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,NT5C3B,TNRC6C,PPFIA3,SFMBT2,ARRB1,TMEM108,ATP2B2,SLC2A11,MTMR9,ADAM23,ARHGEF7,LINC00906,NIPA1,CDK5R2,CACNA1D,CACNA1E,CACNB2,CALB1,CALB2,CAMK2D,VXN,BRSK2,MAP7,CLDN10,USP6,MTMR7,C1orf52,REPS2,DCLK1,LRRFIP1,LGI1,ASIC3,RAB33A,CLCN4,TPP1,FBXO7,ABCG2,C4orf33,NIPBL,AKAP7,ARMC8,SLC4A8,COX4I1,SMARCAL1,CHD1L,CPS1,SEC31B,CS,ARHGEF10,OSBPL3,IPCEF1,VCAN,NCAN,PPP1R16B,ARHGEF4,RUBCN,CYBB,EARS2,DGKG,DAPK1,DBI,AIF1L,DCC,DGCR5,ZBTB24,HEPH,COPS7A,MAGI2,SMG7,SV2A,SEC16A,DLX1,EXOG,USP3,GNE,DTNB,DNAJB6,DYRK1A,ABCC9,KRBA2,E2F5,WDPCP,PHC2,TMTC1,CELSR3,FAM13A,SUGP2,EPB41,NCALD,EFS,MRPL37,TMEM74,MRPL10,EZH1,ATP8A1,TOMM40L,ZNF589,GTF2IRD2,FGF11,FGF12,FGF13,FGR,SCARA3,FLT1,C2orf88,WDR83,NPTN,NSG1,MPP6,ABLIM2,TVP23A,DKK3,GALNT15,GABRB3,GABRG1,CAB39,GAD2,AHCYL1,FAM120B,GALC,ARPP21,ZNF274,TMEM8B,INPP5K,GATM,ALDH1L1,ADAM28,USP19,PPARGC1A,GLS,MSL3,GLUL,GNAO1,GNAS,GPD1,GPR12,TMEM121B,STMN2,GRIA1,GRIK2,ADAMTS13,LINC01089,GSTM5,ADAMTS6,PADI2,HMGCR,ZNF491,CELF5,SMAP1,EID2B,FAM95B1,IL11RA,INPP5B,LRRTM3,JAK1,KCNA1,CDH20,KCNJ5,KCNJ9,KCNK1,TTYH2,SYTL4,VWA5A,FGFBP3,MAN2A2,ZFYVE27,MAT2A,ADAM11,CHIC1,MID1,POC1B,AFF1,XRRA1,MT3,LYRM9,MYO7A,ALDH1L2,CNOT4,NPTX1,OPCML,OPHN1,SNTG1,PC,PCSK2,PDCD2,PDE1A,PFKFB3,SERPINI1,NALCN,TRHDE,ING3,MBOAT7,EPB41L4B,POU6F1,PPP2R5C,RASGEF1B,MAPK4,EPDR1,WBP1L,PTCH1,UHRF1BP1,BDNF-AS,MTMR10,PTPRE,C1orf109,CCDC40,PLEKHB2,NWD1,OXR1,RET,MORC4,RFX5,UBR7,RGS12,CARF,PNMA8A,CCDC25,YY1AP1,SNX22,FBXW7,GLDN,SCN4B,FAM19A1,SEC14L1,SOX6,MRAS,KIF27,ITSN1,AMBRA1,CHD9,FHOD3,BCAN,ANKRD6,ZNF365,BTBD3,KANSL3,SLC6A8,SLC6A11,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,SLC12A2,SLC14A1,TMEM132D,BTBD7,SLC20A2,GKAP1,SMARCA4,SMARCD3,SMARCE1,RCOR3,INAVA,RIMS1,SNCA,CMTR2,SNRPN,SON,NMNAT2,CAND2,MYCBP2,TEX2,CLSTN2,COLGALT2,ITPRID2,NXT2,MAPK8IP3,MPRIP,SEPT8,RGL1,PHLDB1,STX1A,C3orf70,MLST8,EXOC7,TAL1,TBCEL,TMEM136,ANO4,DMXL2,TCF7,TRIM2,CLASP1,CYB561A3,DICER1,ZFPM2,TGFBR3,GALNT17,MTMR14,TMEM9,TLR4,TP53BP1,RASD2,WBP2,ZNF384,RGMB,PDSS1,TTTY15,LRTM2,TTC3,UBE2H,GORASP1,LINC00689,UGT8,PLEKHH2,VLDLR,LAT2,SF1,NDRG4,CELF4,TMEM237,FSTL5,PCBP1-AS1,DHX33,CA10,PRDM8,LMAN2L,CIAPIN1,GAL3ST3,URM1,WIPF2,EPM2A,DOCK8,UBE3B,CERS6,NLRP3,TIGD6,SLC4A10" MicroRNA hsa-miR-936:mirSVR_highEffct hsa-miR-936:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.23E-117 2.37E-113 3.68E-116 3.39E-115 287 1143 "TKTL1,KDM5D,NLGN4X,NME5,TXNDC16,SPOP,BCAR3,FAM135A,CNIH2,PKP4,APC,CACHD1,LRRC4C,API5,MIER1,ARNTL,ASCL1,ATM,STX16,ALDH7A1,NOL4,ADAM23,RGS9,NRP2,CALB1,CAMK2D,P2RX6,SCARB1,DGKI,ARHGEF2,ZMYM4,LGI1,CDO1,LRWD1,NOG,CFL2,SRSF11,CASC2,CLCN3,CNR1,AKAP6,MAGED1,IGDCC3,MFSD4A,HS3ST5,SEC31B,CREM,RBM39,SLC32A1,ANKRD44,SUSD5,ATRNL1,SOCS5,DOCK4,HDAC9,GPRASP1,TCAF1,FRMPD4,TOX,CENPL,MAML1,TMEM170A,DAPK1,SPOCK2,PABPC5,YTHDC1,ZBTB24,HEPH,CNIH3,BLOC1S6,AK5,DLG4,USP3,DOCK2,ABI1,DSCAM,GNE,ECM2,MAMLD1,ABCC5,KRBA2,E2F5,AASDH,TSPAN5,ANKRD46,RASGRP1,SH3GLB1,EFNB3,FAM13A,PHF20L1,KMT5B,TMEM35A,CALCRL,TUBD1,VPS13B,EPB41L1,KCNMB2,TMEM74,CDKL3,ADGRV1,CLVS1,TAOK3,CEP78,FDFT1,FGF12,TMEM164,SYNCRIP,FLNC,FAM49B,ZNF605,MPP6,PHYHIPL,STAG2,MEGF11,GABBR1,GABRA1,GABRA2,CHL1,GABRB3,JPH4,MTHFD2,ZNF559,GART,PCDH17,PPARGC1A,GLI2,ZNF638,GOLGB1,LILRA1,GRM5,FAM222A,ZHX1,LINC01102,HTR5A,IGSF1,KCNK2,KIF5A,KTN1,L1CAM,HECTD2,NCOA7,ZNF667-AS1,MAP6,MBNL1,AFDN,ZNF680,CCDC80,MSR1,NAP1L1,P2RY13,NCAM1,NDUFA5,NELL1,NEK1,NELL2,NF1,SLC11A2,OGG1,GPR137C,CNTN3,GPR85,PFKFB2,XRN1,PLCB2,PLIN1,ZNF426,MTRF1L,PSAT1,RETREG2,POU3F2,PPM1B,PPP2R5E,PPP3CA,EPDR1,HYDIN,DIRAS2,PROX1,MASP1,SAMD9,CNTLN,STK32A,ZIK1,PTPRE,PTPRH,PTPRN2,PTX3,MARCH1,TMEM255A,ACSS3,RAP1GDS1,OXR1,RASGRF1,SEC61A2,RIC8B,NUDT11,ELP2,RPE,BAALC,KIAA0895L,MEG3,CLIP1,HOGA1,SCN3A,SCN7A,LINC00461,ELMOD1,SELL,KIF27,TRA2B,HSPA4L,SCAF8,NLGN4Y,CPEB3,SHC4,MAGI3,SLITRK3,NLGN1,ABLIM3,SLC2A5,SLC8A3,CCDC88A,BTBD7,CPEB4,SORCS3,SNRPN,RBM34,DOP1A,BDP1,ENKUR,RBM26,LMO3,CLASP2,ZC4H2,NKAIN2,SS18,ERBIN,ELOVL4,RGL1,NECAB1,ARHGEF9,SYT4,CAMSAP2,UNC5D,TRIM2,WASHC4,PCDHB15,RALYL,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,SIRT1,CRB1,LEFTY2,AP4E1,TGFBR3,THRA,HEY2,TPD52,ZMYND8,DCBLD1,RUSC1,ZKSCAN5,CADM1,MEAF6,RICTOR,FMN2,NDRG4,ZNF142,ZNF184,ANKS1B,CA10,EMSY,EVI5,PRDM8,RTN4,PAK5,ADAMTSL3,ZNF248,MSRB3,SLC4A10,GAN" MicroRNA hsa-miR-664:PITA hsa-miR-664:PITA_TOP PITA 5.01E-117 2.81E-113 4.35E-116 4.01E-115 223 679 "KCNH8,ABHD6,ARID1A,CSMD3,ADD3,PWWP2A,AP1B1,OSBPL6,OSBPL8,BCAR3,GPRASP2,OGT,CDC42BPA,LRCH2,PKP4,PARG,MAGEE2,AQP4,CDC14B,SEMA4G,PPP4R4,RGS20,CADPS,SLC4A4,ADGRB3,BMP7,DST,SGCE,CALM1,CDC42,DCLK1,ARHGAP33,LGI1,DLGAP2,SOCS6,B4GALT6,SLIT2,NRXN3,QKI,CNR1,ARMC8,SLC25A27,ABI3BP,AHCTF1,BAG4,IGDCC3,PNKD,NCOR2,TENM4,SEC24C,CTNND2,CYBB,HDAC4,LONRF1,MATR3,BRINP1,SPATA2,MYEF2,CEP170,BLOC1S6,SNAP91,WDR20,DMD,DYNC1I1,DMTF1,DPYSL2,E2F5,RASGRP1,SIDT2,RBM12,MBNL2,RGS17,EMX2,EN2,RCAN2,KCNMB2,GPHN,SRRM1,NCALD,NRN1,ZIC4,ATP8A1,SEC24B,SPSB4,SUCO,HPCAL4,CAP2,STAU2,FUT9,OGA,STAG2,MEGF11,GABRB3,CAB39,AHCYL1,IQGAP2,MSTN,SESN1,SPIN1,EML4,GRIA2,GRIA4,PTPRT,KIF3A,ADAMTS6,MAP4K5,KLF12,BACH2,HLF,NEGR1,AGFG1,HSF2,IRF8,C5orf24,BRINP3,LRRTM3,KCNA4,KCNK2,KCNMA1,IPO5,LIFR,SMAD1,GPR155,MAP2,MAP4,MAT2A,MATN2,MBNL1,CHIC1,MEST,POC1B,MKLN1,HS6ST3,MXI1,NEFH,NFIA,NNAT,NOVA1,IGSF11,GPR137C,KCNK10,PDE4D,PDPK1,GPR85,GNG2,PIK3C2A,ZNF655,CCSER2,FAT3,POU3F2,MINDY2,PKN2,CNNM2,TMEM260,PTPRD,PTPRN2,TMEM255A,USP47,ZNF793,ARID4A,GAL3ST4,FIGN,RFX3,RGS4,PBRM1,ZNF532,LGR4,SYNDIG1,RTN1,SATB1,ATXN1,ELMOD1,SCAF8,NLGN4Y,FAM102A,SH3GL3,CHD9,NLGN1,SLC1A2,PKNOX2,CCDC88A,CPEB4,SNAP25,MBD5,KDM4B,MYT1L,SOX5,SOX11,ZNF423,RBM26,ITPRID2,SEPT3,SYPL1,ANKRD28,TACC1,ACSL6,TCF4,DMXL2,ZFP90,ZEB1,TRIM2,AKNA,AHCYL2,DICER1,SIRT1,SLC44A1,NR2E1,ERCC6L2,RIMBP2,NR2C2,CADM1,UBE3A,SLAIN1,VSNL1,ZIC1,ZNF28,FMN2,LYPD6,CSDE1,PRDM8,SNX27,PAK5,ST8SIA2" MicroRNA hsa-miR-1183:mirSVR_highEffct hsa-miR-1183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.00E-117 3.37E-113 5.20E-116 4.79E-115 277 1066 "CSMD3,GALNT13,SLC12A5,KIAA1211,PTCHD1,ADRB2,BEND6,SLC44A5,ZNF608,RTL9,TXNDC16,HFM1,CDC42BPA,ANK3,CNIH2,APC,UPRT,ALS2,SHTN1,TMEM263,ZFYVE28,CADPS,ASPH,ZBTB10,ATP2B3,RNF182,BCHE,CFLAR,ARHGEF7,FUBP1,MTMR2,CA8,CAMK2A,VXN,KRIT1,CD81,CDC27,CDH8,CDH10,LGI1,LOC730101,TIGD7,CFL2,SRSF11,CHN2,CNOT8,KMT2C,RAB33A,HECTD1,NIPBL,CNN3,SLC4A7,TBPL1,RTTN,CNRIP1,SLC35F1,SEC31B,CREM,RNF14,NCOR1,CS,MROH8,CSF1R,FEZ2,ATRNL1,ERC2,NRSN1,KCTD8,DAPK1,DNAJC6,ZEB2,MYEF2,TIAM2,COPS7A,GSDME,PLPPR4,NTM,FAM107B,DLG2,USP3,CDON,ARRDC4,E2F6,EDIL3,SEZ6L2,WDPCP,EDN3,RASGRP1,SEMA3D,KLHL5,FSD1L,SUGP2,RGS17,TMEM35A,CALCRL,DCTN4,TUBD1,EPB41L2,KCNMB2,CEP85L,F3,F8,SCML2,ST3GAL6,KIAA1109,SPSB4,SUCO,ATP5PD,SGIP1,SMC2,ARFGAP2,ATP2C1,ERGIC3,ST6GALNAC3,FYB1,STAG2,GABRA1,NCKAP1,ERAP1,SULT1C4,MSTN,ARFIP1,PCDH17,GGT7,GHR,PPARGC1A,GK,PCDH11X,RAB40B,FERMT2,PSRC1,GPM6B,PCLO,GRIA2,GRM5,MFSD2A,PSIP1,MAEL,RASSF8,HPS5,VSIG4,HMGB1,ZNF491,NEGR1,NKD1,IL6ST,INPP5B,LRRTM1,ITGAV,KCNA2,KCNJ10,KCNJ11,STXBP5,NCOA7,SMAD1,SMAD9,MARK1,MAT2A,MBP,LRP1B,POC1B,MOBP,ZNF680,MSI1,MSRA,MYO9A,RTL5,TCEAL5,NEK1,NF1,NHLH1,VWA2,SLC11A2,NTRK2,NUCB2,OPA1,CNTN3,PDE4B,GPR85,BEST3,CYTL1,NALCN,PIK3C2A,ANLN,KCTD15,PLP1,MTRF1L,FA2H,PPM1B,LRRN3,PRKACB,PKN2,EPDR1,MAPK9,DIRAS2,MASP1,PTAFR,PTCH1,PTPRD,PTPRZ1,STRC,PPP2R3C,RAP1GDS1,ARID4A,SLC6A15,ERI2,SEC61A2,RNASE1,RPRD1A,CCDC82,CARF,RORB,YY1AP1,CCDC102B,RPE,TMEM100,RPL15,ARMH4,ATXN2,LRFN5,FAM19A1,TRA2B,SH3BGR,FERMT1,WDR47,SEPHS1,ATF7IP,SMARCE1,MBD5,TMCC1,PDZD2,SOX2,TNIK,ITPRID2,NKAIN2,SULF2,VPS13A,SYT1,TMEM136,MGRN1,ANO4,TCF4,DMXL2,ZFP90,TCF7L2,ZEB1,WASHC4,TEK,TJP1,ACTR6,BHLHB9,AMACR,STXBP4,TRPS1,TMEFF2,UBE3A,OSBP2,RBFOX3,NSD2,ZFP37,ZIC3,KCNT2,PLPPR5,CA10,PMEPA1,CADM2,HPS4,TMEM163,GOPC,FZD3,DOCK8,HNRNPA3,RNF170,VANGL2,NHSL1,FXR1,NETO1" MicroRNA hsa-miR-185:mirSVR_highEffct hsa-miR-185:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.14E-117 4.57E-113 7.05E-116 6.49E-115 311 1342 "VWA5B2,KCNH8,CLK4,KDM5D,ARID1A,NDRG3,DSCAML1,SLITRK1,ADD2,PTCHD1,KLHL13,ZNF578,SPOP,PCDH10,ZNF687,USP28,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,APP,MIER1,PLA2G4C,ATP1A3,CADM3,TTLL9,BACH1,ADGRB1,ADGRB2,CFLAR,MTMR2,THSD7A,KALRN,PTBP2,SLC25A14,VXN,LDB2,USP2,MTMR7,TMEM257,SYNGR3,DGKI,CDC42,LGI1,SRSF11,CASC2,SYNPR,JAM2,LHX2,CPNE6,PPT2,COG1,CNGA3,TMEM155,PCYT1B,ARMC8,AKAP6,SUMF2,COL9A3,SLC4A8,ZFP28,SLC35F1,PREPL,GDA,ABCG1,FEZ1,OSBPL3,CSNK1G3,NCAN,PDE4DIP,UBXN2A,CTNND1,NRSN1,USP6NL,TCAF1,RIPOR2,DCAF8,TBC1D5,DGKB,PITPNC1,SPATA2,HP1BP3,KLHL3,ZC3H11A,SMG7,SV2B,CHRDL1,DMD,DNM1,DTNA,ABCC9,EBF1,SEZ6L2,FAM135B,FRY,RBM12,GPR61,PHF20L1,APH1A,EBI3,ING4,TMEM35A,EIF1,EPB41L1,RRAGB,DLC1,RACK1,ST3GAL6,POLR1B,FGR,POLK,SUCO,EFCAB2,NPTN,STAU2,TBR1,ABLIM2,ZNF512,GABRA3,AHCYL1,GALC,GAP43,DISC1,INPP5K,GATM,TUBGCP4,BRD8,TOX3,MSL3,STARD3,ZNF638,KDM2B,DCLK2,GOLGB1,PRUNE2,CCDC184,PCLO,GRIA2,GRIA4,PLCD4,SERP2,FAM19A2,KAT7,GSTT2,SOX21,FAM222A,MAEL,RASSF8,UBE2QL1,PTGDR2,PACSIN2,VSIG4,ACOT7,HMGCL,HSP90AA1,FAAP20,ZNF678,INPP5B,LRRTM1,KCND1,KCNN2,KCNN3,KLC1,CYP27C1,INSYN2,MAP2,MAP4,MAT2A,MDM4,MEIS1,SRSF12,MOG,MSI1,MSRA,MYO9A,RTL5,PABPC1L2A,NDUFA5,NINJ2,GLIPR1L2,PAK3,PCDH9,CDK18,PDE1C,CCSER2,PLCB2,PRIMPOL,RC3H2,SLC36A4,PPP2R5C,PRKACB,WDR25,PSMD13,CNTLN,PTPN13,PTPRE,QDPR,FAM66C,FAM184A,ZCWPW1,RDX,TRIM68,DPF2,PRRT2,MORC4,SLC25A36,RPRD1A,SETD5,KLHDC8A,CARF,RPE65,LRRK2,ABCA11P,ATAT1,WLS,ZNF568,TRAPPC13,FAM192A,ATXN1,ATXN2,LRFN5,HOGA1,SCN2A,TNFRSF19,ASIC4,SH3BGR,MYO18A,ANKRD6,BTBD3,SLC6A1,SLC8A1,CDK5RAP3,SLC11A1,CPEB4,ZKSCAN3,SMARCC2,SORCS3,SNAP25,UNC80,KDM4B,SOX5,HECW1,SPTB,DDN,CLASP2,CLSTN2,SMOC1,SSTR2,ZC4H2,INKA2,ELOVL4,PHLDB1,ZC3H4,ZFR2,VPS13A,FNDC9,SYN1,TMEM150C,ASTN2,EHBP1,TPCN2,TCF12,WDR7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,AP4E1,CDH22,GALNT17,MTMR14,TJP1,HEY2,TNR,NPL,CHST5,ZNF384,ELP5,TSN,CA14,TSC1,SSBP2,TTC3,RPL7L1,UBE2H,OSBP2,MGAT5B,BEST1,WIPF1,NPDC1,SF1,CELF4,LAMP5,MEIS3,SLC30A3,CA10,HPS4,MDH1B,URM1,NAV2,SLC17A7,PARP11,KAT6A,CAMK1G,KLHDC1,IFT88,NETO1" MicroRNA hsa-miR-142-3p:mirSVR_lowEffct hsa-miR-142-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.41E-117 4.72E-113 7.27E-116 6.69E-115 285 1130 "ACTN1,SORCS1,RTL9,NME5,ALCAM,AMPH,ANK2,PPFIA2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,VAT1L,USP37,APP,MIER1,PPP4R4,CASK,RGS20,ASPH,BRINP2,ZBTB10,NUMB,MTMR9,N4BP2L1,RIPK1,MIR9-3HG,BID,CDK5R1,FUBP1,SCAPER,CA8,DDR1,CALM1,VSTM2A,CBLN1,INA,ARHGEF2,LRRFIP1,LGI1,MAGI1,CACNA2D2,SOCS6,SYNPR,NRXN3,COG1,NMT2,NIPBL,CNN3,AKAP7,ABI3BP,RCHY1,TBPL1,ACBD5,ZFP28,HS3ST5,FAM171B,C2CD2,CREM,HAPLN1,OSBPL3,NCAN,PDE4DIP,FAM169A,DZIP3,PPP1R16B,PHF14,PLCXD3,PNPLA8,CTNND1,BOC,RIPOR2,TOX,KIAA0513,IST1,DBI,ARMCX4,ELMSAN1,TMEM130,SPOCK3,AK5,DPH1,DRD1,PDCD6IP,DTNA,ABCC5,DNM1L,EBF1,USH1C,KLHL5,SH3GLB1,PHF20L1,EGFR,TMEM132E,KCTD3,ELAVL2,RGS17,EMX2,LRRC17,STX2,EFS,ZNF549,NSRP1,FAM198B,RPS6KC1,GORAB,FGFR3,FLT1,SGIP1,TACC2,ATP2C1,ZNF605,STAU2,KBTBD12,GAB1,GABRG2,ILDR2,BRPF3,NCKAP1,LRRC37A6P,SULT1C4,MSTN,CYP46A1,GLI2,LUZP2,LNX1,PRUNE2,GRIA1,GRIA2,GRM3,GRM5,FAM19A2,LINC01551,GUCY1B1,MAEL,RASSF8,ZHX1,LINC01102,SCRG1,IGF1,DOCK7,PLD5,ITGAM,OLFM3,KCNA4,KCNH2,KCNJ10,KCNQ3,KIF5A,KIF5C,KLRC2,SYTL4,ARHGAP12,NCOA7,LSS,ZFYVE27,MAP2,MARK3,MBNL1,SYT9,TM6SF1,MDM4,AFF1,AFDN,MOG,SESN3,ADAM22,MSR1,NAP1L2,NCAM1,NEUROD2,NFE2L2,NOVA1,NTRK2,SETD4,GPR88,OPHN1,DPY19L2P2,ETFRF1,PCSK5,ANLN,XRN1,PLCB2,EPN1,PCDH18,SLC36A4,FAT3,POU3F4,CCDC144B,PPP2R5E,CEP41,RELN,LRRC49,SIDT1,WDR25,BDNF-AS,PTPN13,PTPRB,TUG1,ZNF793,RBBP6,KHDRBS2,ERI2,RGS12,SEC61A2,RPRD1A,ZNF532,CARF,MCMBP,GLDN,ATAT1,S100B,AMER2,ATXN2,FERMT1,MAGI3,FBXO11,CCDC92,CPEB4,SMARCE1,SP4,ERC1,RBM26,NPAS3,RAP1GAP2,LMO3,ITPRID2,ZC4H2,SS18,TMEM150C,ANKRD28,FBXW11,TBL1X,EHBP1,VWC2,SATB2,TCF7,ZEB1,TRIM2,DOCK9,RALYL,ARHGEF12,HIF3A,SIRT1,C18orf54,AKTIP,THBS4,GZF1,TIAM1,TJP1,ZFP91,RIMBP2,RBFOX2,TPD52,TPM3,TPM4,SYNPO2,SMUG1,ZMYND8,TUBB1,UBE2H,VLDLR,CLDND1,PCDH20,ZNF540,ZNF138,ZBTB38,ANKS1B,ZNF195,PRDM2,NT5M,EVI5,PRDM8,PCDH15,FAM47E,PLSCR4,FAM13C,AMN1,FZD3,CERS6,ACTR3B,JMJD1C,TIGD6,NHSL1,FXR1,NETO2,FAM198A" MicroRNA hsa-miR-744*:mirSVR_lowEffct hsa-miR-744*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.66E-117 4.86E-113 7.43E-116 6.85E-115 342 1611 "CSMD2,CSMD3,TMEM132B,GALNT13,ADORA1,USP31,BEND6,KIAA1324,CC2D2A,HFM1,C1QTNF3,FAM135A,PDZD4,PITPNM2,LRCH2,ANK3,PHF12,PKP4,APBB2,DGKZ,UPRT,APP,LGR5,KIAA1614,PLA2G4C,ARSE,NUMB,ATP1A2,SLC2A11,MTMR9,N4BP2L1,DPY19L3,SNAI3-AS1,BCL2L2,GPR146,SYNJ2,ARHGEF7,CASTOR3,RAB29,IL33,CABP7,THSD7A,SPAG9,LDB2,METTL6,CCNH,LGI1,CLGN,NUMBL,MS4A7,RAB33A,NRXN3,CLTA,TJP2,QKI,IQCK,AKAP6,SUMF2,ABI3BP,ZFP28,PREPL,HAPLN1,GDA,ABCG1,SNCAIP,MICAL2,IPCEF1,SOCS5,PHACTR3,KIAA0040,UBXN2A,CTH,GREB1,PUM1,RIMS2,ST18,CCDC144A,ARHGAP32,TCAF1,CENPL,TBC1D5,KIAA0586,KCTD8,DNAJC6,ZBTB24,KIAA0753,SV2B,SV2A,NTM,G3BP2,DLG2,EXOG,DNAH9,DMTF1,CASP8AP2,ATN1,ARRDC4,DYRK1A,ABCC9,GOLT1B,WDPCP,EDN1,EDNRB,HIPK3,KLHL5,RBM12,PHF20L1,SUGP2,KMT5B,EGR3,EIF4G2,ELN,EPB41,EPHA5,EXTL2,NSRP1,RPS6KC1,TBC1D16,TMEM132C,PTK2B,TOMM40L,ZNF589,SLC9B2,GTF2IRD2,SUCO,IQCG,ATP13A4,FLT1,TMEM107,ARFGAP2,PNMA2,MPP6,PHYHIPL,GABRA2,GAD2,AHCYL1,ERAP1,MTHFD2,ACSS1,TUBGCP4,GFRA2,LYVE1,TOX3,PRLHR,RAPGEF4,STMN2,GRIA2,PLCD4,GRIN2C,NR3C1,GRM3,TMEM25,AP4S1,FAM107A,MAP4K5,HPS5,HLF,HNMT,ZNF491,SMAP1,HTR2A,HTR5A,BTBD17,FAM95B1,ZNF546,LRRCC1,SCIN,INPP5B,ITPKB,CDH20,KCNB1,KCND1,KCNK1,CYP27C1,LAMP2,PAXBP1,LMO2,MBNL1,MEIS2,MIA2,KITLG,SCAMP5,MOG,MSRA,N6AMT1,CTNNA3,MTR,NEXMIF,NDP,NFE2L2,VWA2,NOVA1,DNHD1,SMIM11A,OPCML,OXTR,PCDH9,PCSK1,PCSK2,PDE3B,GPR85,ZNF655,ZFYVE21,LRP12,FAT3,SH3KBP1,PPARA,CCDC144B,LRRN3,PPP3CA,PRKAB2,WBP1L,SYTL2,LAMA1,GON4L,PTAFR,PTHLH,PTPRB,OCIAD1,PTPRD,PTPRH,PTPRO,ACSM5,TUG1,ZNF793,FAT4,OXR1,KHDRBS2,ERI2,RFX4,PBRM1,TMLHE,ARMH4,FBXW7,KIAA0895L,ADAL,SYNDIG1,MEG3,ABCA11P,SALL1,SCN2B,SCN8A,LINC00461,FNIP1,IL17RB,TRA2B,NLGN4Y,ZFP30,ITSN1,AMBRA1,ST6GAL1,ANKRD6,ZNF365,SLC1A6,ZNF430,SLC9A5,BTBD7,ZFP1,SMARCE1,ANKRD36,SNAP25,KDM4B,PDZD2,SOX5,FNBP1,HECW1,KDM4C,TSPYL2,RBM26,POGZ,ELOVL4,SULF2,GSE1,FAM168A,SYNE2,ARHGEF9,SYP,TAL1,CNTN2,TBCEL,TCF7,AZIN2,SLC19A3,PSD3,OBSL1,AHCYL2,TEX15,CYB561A3,FAM200B,ITGB3BP,TGFBR3,HHIP,ARL10,DDHD1,TP53BP1,TPM1,TPM3,ZNF346,ELP5,PDSS1,NEIL2,STXBP4,TRPC1,TRPC3,SGK3,RPRM,SLC35A4,BCL2L13,VLDLR,VSNL1,RBFOX3,LAT2,NSD2,RICTOR,ZIC2,ZNF24,ZNF28,TRIM9,ZNF177,ANKS1B,SPIRE1,ZNF213,PRDM8,HPS4,SIGLEC10,SLC17A7,SLC17A6,PDSS2,RGS7BP,DNAH10,FAM13C,FZD3,SMIM8,TMEM63C,FBXO36,ZNF248,TIGD6,MSRB3,NHSL1,FRMD6,LAS1L,SENP7" MicroRNA hsa-let-7g-5p:TargetScan hsa-let-7g-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7e-5p:TargetScan hsa-let-7e-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7a-5p:TargetScan hsa-let-7a-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-miR-98-5p:TargetScan hsa-miR-98-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7i-5p:TargetScan hsa-let-7i-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7c-5p:TargetScan hsa-let-7c-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7b-5p:TargetScan hsa-let-7b-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7d-5p:TargetScan hsa-let-7d-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-let-7f-5p:TargetScan hsa-let-7f-5p TargetScan 8.73E-117 4.91E-113 7.43E-116 6.85E-115 251 873 "PLEKHH1,GRAMD1B,ADRB2,INTS2,MTUS1,KLHL13,CASKIN1,PCDH19,KCTD16,ARHGAP20,FAM135A,BEGAIN,AMT,LCORL,MAP4K3,GAS7,AMER3,IGDCC4,CASK,CHRD,NCOA1,ATP2A2,ATP2B3,ADAM15,BACH1,BCL7A,DST,ARHGEF7,MTMR3,GYG2,CACNA1I,NIPA1,BSN,CACNA1E,CACNB4,CALM1,CAPN3,RUNX1T1,AIFM1,CD86,NUMBL,CFL2,MAP4K4,IGLON5,PCYT1B,ARMC8,AKAP6,COL4A5,COL9A1,BTF3L4,COL9A3,AKAP5,AHCTF1,MYRIP,IGDCC3,SEC31B,CLOCK,CRY2,NCOR1,OSBPL3,PLXNA4,PITPNM3,PPP1R16B,PLCXD3,GREB1,SEC14L5,CCDC144A,DCAF8,RIMS3,DAPK1,CTIF,DNAL1,B3GAT3,MFAP3L,BLOC1S6,GRIN3A,DMD,CALN1,CPEB2,DPH1,ARRDC4,DUSP9,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,EDN1,ANKRD46,RASGRP1,GPR61,EGR3,PLXNC1,AASS,GOLGA7,EIF4G2,CERCAM,RGS17,PLEKHO1,CEP85L,APC2,RCSD1,KATNAL1,EZH1,DLC1,FGF11,SCARA3,PCYOX1,ANKFY1,AFF2,C2orf88,RASL10A,CELF1,B3GAT1,MEGF11,DKK3,GABRB1,GALNT15,GALC,SALL3,C15orf41,GATM,FAXC,CYP46A1,GHR,PPARGC1A,LYVE1,RAB30,KIAA1958,GNAL,GPR26,CECR2,CNTRL,GRIK2,CACFD1,ADAMTS8,PRDM5,RNF165,LINGO1,HAS2,FRMD5,DDX19B,HLF,IGF1,NKD1,RBPJ,PLD5,IGSF1,IL6R,SCRT2,KCNA6,KCNC1,KCNC2,KCNJ3,KCNJ11,KLHL23,KIF2A,KPNA5,HECTD2,NAT8L,MDFI,CHIC1,MDM4,MEF2C,MEIS1,MEIS2,RSPO2,MYCN,NAP1L1,NEFM,NME4,NOS1,NOVA1,OLR1,GPR137C,PBX1,CDK14,KCTD15,PRRX1,PPP3CA,PRKAB2,PKIA,PKN2,MAPK8,GDPD1,CNNM2,PTAFR,PTPRD,ATG16L1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,RAVER2,CYB561D1,ROBO1,KIAA0895L,ATP8B4,ACER3,RIMKLA,LGR4,CSRNP3,SCN4B,SCN8A,FNIP1,SEC14L1,ITSN1,CPEB3,CHD9,FNDC3A,DZIP1,BTBD3,FAM214B,RADIL,CPEB4,KIF21B,BDP1,KDM3A,PEG10,DDN,CLASP2,POGZ,NXT2,ELOVL4,ANKRD28,FAM208A,ACSL6,KIAA0930,FAM189A1,NSD1,HIF3A,DICER1,CDH22,CBX5,RBFOX2,PDSS1,PRR18,FAM155A,AMOT,RICTOR,PCDH20,CRB2,REEP1,CADM2,RGMA,MVB12B,GOPC,FZD3,RNF170,GAN" MicroRNA hsa-miR-3152:mirSVR_lowEffct hsa-miR-3152:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.49E-117 5.33E-113 8.07E-116 7.43E-115 314 1368 "ACLY,TKTL1,TMEM132B,SLITRK1,GALNT13,SORCS1,PTCHD1,KIDINS220,MTUS1,PCDH19,RTL9,TBC1D14,AK2,SEMA6A,FAM135A,ZNF687,LCORL,MAP4K3,PPFIA1,APC,GPAM,LGR5,SEMA4G,TMEM263,CASK,ASCL1,ZBTB10,ATP2B1,ZNF583,N4BP2L1,DPY19L3,KIF1A,TTLL9,BID,KSR1,ARHGEF7,MTMR2,BSN,PTBP2,CAMK2G,VXN,SPAG9,INA,LRBA,CDC42,CACNA2D2,DIS3L,CHN1,RAB3C,KMT2C,NRXN1,CLU,IGDCC3,MFSD4A,PNKD,CLOCK,PREPL,C1QL2,SNCAIP,LRIG1,NCAN,ARHGEF4,DOCK4,RIPOR2,DCAF8,LONRF1,KIAA0586,SPATA2,JAKMIP2,MAGI2,SRGAP3,GRIN3A,RAB39B,DMD,DNM2,DNM1L,EDN1,KLHL5,FAM13A,PHF20L1,MRO,MBNL2,LPAR6,ASB3,ELAVL2,PLEKHA1,STARD3NL,USPL1,EPHB1,ERBB2,DENND4A,CEP85L,SIRPB1,MRVI1,ATP8A1,ST3GAL6,MEX3B,FOXG1,FOXF2,ANKFY1,PSD2,EFCAB2,POMT1,PDLIM5,ERGIC3,DACH2,ABLIM2,FYN,PHYHIPL,STAG2,MEGF11,GABRA5,ARPP21,ZNF234,NCKAP1,IQGAP2,ERAP1,KIAA1841,DNER,CSDC2,ZNF276,SPIN1,GLI2,TOX3,GLUL,PCDH11X,GOLGB1,GPM6B,CCDC184,GPR34,GRIA4,SPACA9,GRIN2C,GRM1,LINGO1,GUCY1B1,FAM222A,RASSF8,C1orf94,HMGCR,NEGR1,HSP90AA1,GAREM2,PLD5,INPP5B,OLFM3,KCNJ3,KCNK2,STXBP5,GPR155,LYPLAL1,MATN3,CHIC1,LRP1B,ERICH3,SAMD5,SESN3,ADAM22,BCO1,N6AMT1,NAP1L1,NCAM1,NDP,NELL1,NELL2,NFE2L2,VWA2,CNOT4,NOVA1,SLC11A2,NUCB2,OPA1,OPCML,PCDH9,PCSK2,PDE4B,PDE4D,PFKFB3,NALCN,PIK3C2A,PLCL1,PLP1,MTRF1L,PDZRN4,PMP22,PRRX1,ING3,EPB41L4B,PILRA,NXPH1,PPARA,RANBP3L,PRKAB2,RASGEF1B,PRKACB,PKIA,LRRC49,CNTLN,PTCH1,SPDL1,PTPN13,PTPRZ1,TMEM231,MARCH1,TMEM255A,FAT4,ROGDI,DBX2,RBBP6,VEPH1,BSDC1,DPF2,RGS10,SLC25A36,RPRD1A,PAQR6,SALL1,SEMA6D,SCN2A,SCN7A,SGK1,NTNG1,SHC4,CHD9,SLITRK3,CNKSR2,CTXN2,ZNF365,WDR47,RUFY2,PKNOX2,LRRC55,RAB3GAP1,SIRT2,CCDC88A,SLC12A2,SCMH1,SLC22A4,TET1,SNRPN,FAM219A,MYT1L,BDP1,ENKUR,HECW1,NPAS3,C11orf87,POGZ,ITPRID2,STOX1,EPB41L3,ZC4H2,SS18,SEPT8,GSE1,MLC1,VAMP1,PLCB1,SYPL1,COBL,ATP11A,MTCL1,FAM208A,UNC5D,ADGRL3,KLHL4,ATMIN,SATB2,TRIM2,PCDHB10,OBSL1,FRYL,DICER1,SIRT1,LEFTY2,ZMAT3,TIAM1,BHLHB9,DAAM2,CSMD1,PIK3R5,RGMB,TSN,TSC1,ANO5,TTC3,TUB,UGT8,RBFOX3,WRN,RICTOR,PCDH20,ZIC3,ZNF17,PLPP4,MKRN3,LYPD6,ZBTB38,EML6,ANKS1B,WNK1,EMSY,DNALI1,CSDE1,FAM47E,FAM13C,AMN1,FZD3,VANGL2,FRMD6,IFT88,NETO1,RNF146,CBLN2" MicroRNA hsa-miR-640:mirSVR_lowEffct hsa-miR-640:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.64E-117 5.42E-113 8.18E-116 7.54E-115 306 1301 "RALGAPA1,ABAT,CLK4,NBAT1,CSMD3,ADAR,KLHL32,BRAP,SORCS1,SNX30,ZNF608,WDR35,TAOK1,LRRC7,CARNS1,GOLGA7B,SUGT1P4-STRA6LP-CCDC180,DGKD,SHROOM2,MIER1,IGDCC4,RGS20,ASPH,NCOA1,ATP1B3,ATP2B1,N4BP2L1,DPY19L3,TTLL9,SNAI3-AS1,BBS2,RGS9,CFLAR,ARHGEF7,JAZF1,CACNA1G,BTRC,CA4,CA12,CACNB2,PTBP2,HIP1R,CBS,CBFA2T2,DGKI,AP4M1,REPS2,CDH2,DCLK1,ZMYM4,SRSF11,CHM,CASC2,MS4A7,JAM2,RAB28,KIAA1549L,CLTA,LETMD1,AKAP5,RCHY1,MFSD4A,HS3ST5,CHD1L,CLIP3,ATRNL1,NCAN,PDE4DIP,CMTM5,CTH,NRSN1,EDRF1,ECE2,MYADM,RASSF2,MAML1,DGKB,ARMCX4,C8orf34,DDX46,SMG7,SPOCK3,SGSM2,TMCC2,KBTBD11,DLG3,RAB39B,DMTF1,SLC25A18,ARRDC4,FAM78B,TOM1,DNAJB6,ABCC9,KRBA2,FAM135B,RASGRP1,TMTC1,PHF20L1,MBNL2,PAN3,KCNMB2,RCSD1,SCML2,SLC9B2,GTF2IRD2,AMOTL2,FHL1,POLK,SUCO,FLT1,SLC37A3,ARFGAP2,ERGIC3,NSG2,STAU2,DKK3,HBS1L,ZMYND11,ARPP21,ALDH1L1,GCNT2,GJB1,COPS8,DBF4,GLS,PCDH11X,STARD3,ZNF638,LUZP2,DCLK2,ATF7,MCHR1,PCLO,GRB10,GRIA1,PLCD4,GRM7,MFSD2A,ADAMTS6,IRAK3,HNF4G,ZDHHC15,OPALIN,SHISA6,ICA1,LINC00667,LIX1,IL6R,ZNF385B,CDH20,GATD1,KIF5C,STXBP5,LIFR,SYTL4,ZNF667-AS1,SYT9,LDLRAD3,TM6SF1,MEIS1,KITLG,PPM1L,MMP16,MOBP,ZNF680,DBNL,MSR1,CTNNA3,MYO6,NACA,NFYA,SLC11A2,NRCAM,NUCB2,OXTR,PCSK1,PIRT,PDGFRA,PDPK1,BEST3,CDK14,XRN1,JAKMIP1,ZNF426,MTRF1L,PURG,RETREG2,NXPH1,PPM1B,PPP1R1A,CCDC144B,LRRN3,PRKACB,SLC26A11,MASP1,SIDT1,DEF8,PTHLH,PTN,ZSCAN32,ACSM5,PLEKHB2,FAM66C,ZDHHC14,CRTAC1,DPF2,RET,RGS12,SLC25A36,RIC8B,PBRM1,ATP8B4,HSD11B1L,TMEM156,ATXN2,ATXN7,LRFN5,SCN3A,SCP2,FNIP1,SOX6,STUM,MRAS,ASAP3,NTNG1,CHD9,FHOD3,ST6GAL1,SLITRK3,NUBPL,PAAF1,SLA,SLC1A6,PPP4R3A,SMTN,SLC6A1,KANSL3,ARHGEF40,TMEM132D,TET1,SLIT1,MYH15,MBD5,KIF13A,SNRPN,FAM126B,UNC80,MYT1L,SOX5,BDP1,NMNAT2,ZC3H13,CDK19,TSPYL2,NPAS3,POGZ,SEPT8,DIP2A,ADHFE1,SYNE2,NUDT10,SYN2,ATP11A,CAMTA1,TAL1,FBXW11,VWA3A,EHBP1,SATB2,TPCN2,NAT16,RALYL,DICER1-AS1,SPX,HHIP,ARL10,TK2,TMPO,R3HDM1,NPL,TPM3,SMUG1,TRPC1,TRPS1,RUSC1,TTC3,FLRT2,GUSBP1,ZBTB14,ZNF24,LAMP5,LRP8,STOX2,PRDM8,LMAN2L,RNF103,VPS35L,CAB39L,WIPF2,MVB12B,ST7,NUP214,SOCS4,SLC4A10,SPATA13" MicroRNA hsa-miR-1273d:mirSVR_lowEffct hsa-miR-1273d:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-116 6.48E-113 9.78E-116 9.01E-115 332 1524 "RALGAPA1,NBAT1,SYS1,ARID1A,CSMD3,ADAR,ADARB2,TMEM132B,CCDC85A,SLC12A5,ESYT2,NLGN4X,HECW2,AGT,RTL9,KIAA1324,PCDH10,AMT,OGT,DPP10,ANK3,PKP4,APAF1,EPB41L5,USP37,MIER1,SLC7A14,PPP4R4,ZBTB10,NCOA1,ASTN1,CADM3,DPY19L3,SEC11C,DNAJC27-AS1,SCAPER,CACNA1D,CACNA1E,CALB2,DIRAS1,CALM1,CAMK2D,SPAG9,PRC1,LRRFIP1,CDH18,LARGE1,IGFN1,SOCS6,CASC2,JAM2,ARHGAP22,KIAA1549L,CLCN4,TMEM59L,FAM19A5,ARHGEF6,IQCK,PCYT1B,TBPL1,MYRIP,MFSD4A,CHD1L,RBM39,CRMP1,GDA,CLIP3,TRIM69,RGS6,MICAL2,CSNK1G3,SLITRK5,APPL1,NRSN1,GAPVD1,FRMPD4,TOX,PHF19,TOMM20,IP6K1,ARMCX4,SPATA2,HEPH,ELMO1,POM121,SNAP91,SPOCK3,NTM,GRIN3A,DMD,NR1D2,ACOT8,DRP2,ARRDC4,EBF1,FAM135B,EDNRA,ATL1,RBM12,YAF2,SH3GLB1,PHF20L1,EIF5,IRAK4,USPL1,VPS13B,STX2,ZNF549,ETV1,ABCA8,DLC1,CEP78,FDFT1,ACTL6B,BAIAP2,PRKAG2,CAMSAP1,MEX3B,SYNCRIP,EVL,FLT1,SGIP1,FOLH1,DCTN2,PDLIM5,CSPG5,KBTBD12,TBR1,TVP23A,GABRG2,DENND2A,HBS1L,ZMYND11,GALC,ZNF234,ERAP1,DISC1,INPP5K,AHDC1,MMADHC,GFRA1,PPARGC1A,SPIN1,GLYR1,TOX3,MSL3,LNX1,TDRKH,CECR2,PCLO,RAPGEF1,GRIK2,NR3C1,GRM1,ZNF496,BTN2A1,RNF165,KAT7,ZBTB49,ZHX1,PACSIN2,FRMD3,HLF,GABARAPL2,SYNPO,AGBL5,HSF2,CELF5,MSL1,DOCK7,ITGAV,IPO5,CYP27C1,STMN1,ARHGAP12,NCOA7,PACRG,GPR155,MAP2,MDFI,AFDN,XRRA1,MOBP,CD200,MSR1,ZC3H12B,NINJ2,NTRK2,OGG1,OPA1,KCNK10,PBX1,PCSK1,PCSK5,CDK18,PDE4D,CDK14,NALCN,A2ML1,PLP1,LRP12,PACSIN1,FAT3,NXPH1,SH3KBP1,IRX1,MED1,PKN2,GRAMD1C,SIDT1,GDPD2,PIGG,PTK2,TMEM260,PTPRE,PEX2,RIPOR1,ZSCAN2,TUG1,RASGRF1,RBBP6,RDX,ZYG11B,ERI2,RFX3,RFX4,ARHGEF10L,EXD2,ARMC5,RAVER2,CCDC25,YY1AP1,CCDC102B,SNX22,SPIN3,ATP8B4,MEG3,WLS,NCBP3,DGLUCY,ATXN7,HOGA1,SCN7A,TNFRSF19,MRAS,TRA2B,ITSN1,FERMT1,DOCK10,ZNF365,PEX26,ZNF430,SLC9A5,SLCO1A2,CPEB4,ZKSCAN3,LIMCH1,MAPKBP1,KIF13A,SNRPN,DOP1A,PDZD2,SOX5,KDM3A,CAND2,ZC3H13,KIF1B,LMO3,SRPK2,POGZ,SMOC1,LARP4,ZSCAN29,MLC1,SYN2,SYP,SYPL1,ANKRD28,TACR1,KAZN,TAF9,ADGRL3,TBCEL,ZFP90,TCF7,RALYL,PCDHB10,FRYL,CRB1,ITGB3BP,AP4E1,HHIP,RIMBP2,C5orf64,RBFOX2,TPD52L2,METTL3,PRMT8,PPIL6,UBE3A,AMOT,ZNF709,BCL2L13,TOM1L2,MEAF6,CCDC14,RICTOR,XPO1,PCDH20,ZFP37,FMN2,MKRN3,LYPD6,ZNF154,REEP1,EML6,ANKS1B,ZFAND5,SYNC,EMSY,CIAPIN1,SIGLEC10,NAV2,KCNAB1,WNK3,C12orf4,RGS7BP,UBE3B,HNRNPA3,ADAMTSL3,PIANP,SPATA13" MicroRNA hsa-miR-28-3p:mirSVR_lowEffct hsa-miR-28-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-116 6.91E-113 1.04E-115 9.58E-115 297 1228 "CLK4,ADCY2,ADCY6,GALNT13,ADD1,ESYT2,OSBPL1A,TBC1D14,WDR35,TXNDC16,CEP126,MARCH4,UNC79,FAM135A,MAP4K3,ANXA7,APBB2,MAGEE2,LRRC4C,AQP4,SLC7A14,TMEFF1,ASPH,ATM,ATP1A2,NOL4,DPY19L3,BACH1,DST,SYNJ2,LINC00906,BTK,WASF1,CACNA1D,CACNB4,CALB1,SYT6,RUNX1T1,CBLN1,USP6,LRBA,LRRFIP1,CLGN,SRSF11,FOXN3,SOCS6,CHM,SYNPR,TAOK2,COG1,TPP1,QKI,MAP4K4,NIPBL,AKAP7,PCYT1B,FAM149A,AKAP6,AKAP5,ACBD5,CREM,AKAP12,CSF3R,OSBPL3,SIPA1L1,FAM169A,CTNND2,CCDC144A,HDAC9,LONRF1,MATR3,DGKG,ARMCX4,DNAJC6,ZEB2,MAGI2,BLOC1S6,PLPPR4,SV2B,WDR20,FAM107B,ARNT2,GRIN3A,USP3,NR1D2,RCAN1,DYRK1A,ABCC9,E2F5,EIF4G2,EPS8,NCALD,DNAJC27,ABCA8,FAM198B,RACK1,ZNF589,POLK,MEX3B,FOXF2,C2orf88,SORBS1,PDLIM5,KHDRBS3,CELF1,AP4B1,GABRA1,HRASLS5,GABRA3,GABRB3,GABRG1,CAB39,GALC,ZNF274,GAP43,ZNF559,DISC1,PPARGC1A,TCERG1,GLYR1,PCDH11X,PRLHR,NUDT21,CLASRP,RNF165,RABL2A,SOX21,PSIP1,ADAMTS6,GUCY1B1,ZHX1,MIER3,VSIG4,SCRG1,ZDHHC15,NEGR1,SHISA6,SMAP1,IGF1,GAREM2,SCIN,JAK2,KCNC2,KCNJ9,KCNMA1,KIF5C,STXBP5,LIG4,VWA5A,MAP2,MATN2,SYT9,KITLG,CD200,SAMD5,SESN3,MYO6,MYO9A,NDP,NEK1,NOVA1,OPHN1,LOC100128398,P2RY1,CNTN3,PAX6,PCSK1,PDE1A,PIRT,SLC10A4,BEST3,PFKFB2,CCSER2,ZFYVE21,XRN1,PLIN1,PURG,PDZRN4,STRN3,LRP12,ING3,EPB41L4B,POU3F4,PPARA,PPP2R5C,PPP2R5E,PRKAB2,PRKACB,HYDIN,QRICH1,UHRF1BP1,PTPRZ1,TUG1,CEP97,PLEKHB2,RASGRF2,KHDRBS2,ZDHHC14,PBRM1,RNASEL,TMLHE,CARF,ROBO2,CCDC25,ARMH4,ADAL,CLIP1,AMER2,LINC00461,SCP2,IL17RB,SOX6,GALNT10,ASRGL1,KIF27,TRA2B,COPZ1,HSPA4L,ITSN1,ARX,CPEB3,DOCK10,MAGI3,FBXO11,FNDC3A,CNKSR2,CTXN2,WDR37,SLC1A3,PPP4R3A,SLC6A1,SHANK2,SLC12A2,RCOR3,MBD5,WDTC1,BDP1,SOX11,KDM3A,SP4,NMNAT2,ENKUR,EMC1,TEX2,ZC3H13,C11orf87,CLSTN2,EPB41L3,NXT2,SEPT3,KLHL7,SUPT5H,PRRC2C,VAMP1,NUDT10,TACR1,DDHD2,UNC5D,ADGRL3,MGRN1,DMXL2,ZEB1,CLASP1,DOCK9,AHCYL2,SIRT1,CRB1,TJP1,NPL,TPM4,ZNF346,PDSS1,TRPS1,DCBLD1,ANKRD20A2,TSC1,TUB,TMEFF2,GORASP1,OSBP2,PLEKHH2,WIPF1,XPO1,XRCC4,ZIC2,FMN2,NDRG4,ZBTB16,SPIRE1,PLPPR5,CADM2,NAV2,RGS7BP,DNAH10,CERS6,SSPN,SOCS4" MicroRNA hsa-miR-651:mirSVR_lowEffct hsa-miR-651:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.32E-116 1.30E-112 1.96E-115 1.80E-114 330 1510 "C3orf14,NCKAP5,CSMD3,ADCY8,KIAA1211,SLC24A4,SLC44A5,KCTD16,NME5,WDR35,TAOK1,SEMA6A,ALCAM,OGT,ANXA7,APBB2,UPRT,VAT1L,BCAS1,USP37,SLC7A14,TMEFF1,CADPS,ATP2A2,ATP2B3,N4BP2L1,NOL4,SEC11C,BCHE,BMP7,GYG2,BSN,CA8,CACNA1D,CAMK2B,VSTM2A,ISPD,INA,LRBA,CDH8,DCLK1,ZMYM4,CHM,RAB3C,KIAA1549L,QKI,HECTD1,CNN3,AKAP7,AKAP6,COL4A5,AKAP5,RTTN,MYRIP,CNRIP1,MFSD4A,CREM,HAPLN1,TRIM69,SNCAIP,CSF1R,SEC24C,CSNK1E,OSBPL3,SUSD5,ATRNL1,PHACTR3,DZIP3,PLCXD3,EDRF1,DOCK4,RIPOR2,ZFYVE16,RASSF2,KCTD8,DAPK1,SIRPA,DNAJC6,CEP170,MAGI2,PLPPR4,SRGAP3,MTX3,WDR20,DLG2,DYNC1I1,DPYSL2,DRP2,PDCD6IP,ECM2,MAMLD1,ABCC9,E2F5,ATL1,SYT15,KLHL5,FRY,EIF5,EML1,PAN3,USPL1,TUBD1,SEZ6,GPHN,ETV1,RRAGB,KATNAL1,HSPA12B,F8,WAC,FABP7,TMEM132C,FCGR3A,GTF2IRD2,KIAA1109,FGF12,BAIAP2,AMOTL2,PRKAG2,UBE2E3,CAP2,ANKFY1,C2orf88,TPK1,ZNF605,ST6GALNAC3,DLL3,MPP6,FYN,STAG2,GABRB1,GABRB3,GABRG1,HBS1L,ZMYND11,ARPP21,DISC1,DNER,GBX2,ALDH1L1,MSTN,AHDC1,GFRA1,USP19,GGT5,BRD8,TCERG1,SPIN1,GLS,TOX3,INSM2,LUZP2,WDFY3-AS2,GPD2,PRUNE2,GPM6A,ATF7,STMN2,GRIA2,CIT,AP4S1,FAM222A,WIF1,LINC01102,BACH2,MIER3,HLF,ELOVL5,SHISA6,HSP90AA1,MSL1,SHISAL1,MYLK2,IGF1,ZIC5,IL6ST,ZNF385B,ITGA7,ITGAV,SYTL4,MARK1,MBNL1,CHST6,CHIC1,LDLRAD3,MEF2C,MEST,MIA2,ZNF680,COL28A1,MSI1,BLOC1S2,DDX25,HS6ST3,MYO6,NAP1L3,NASP,NCAM1,NF1,NUCB2,NUMA1,CHAMP1,OXTR,CNTN3,PCSK2,PDE4D,ENPP2,PFKFB3,SERPINI1,NALCN,PIK3R1,RETREG1,PURG,LRP12,ING3,SPATA6,FAT3,NXPH1,PPARA,TATDN3,RANBP3L,SAMD9,WBP1L,LRRC49,APTX,PSMD13,MTMR10,PTHLH,PTN,PEX2,TMEM255A,RASGRF1,RADX,ZMAT4,GTDC1,RPRD1A,ZFHX4,SETD5,EXD2,C12orf49,CCDC102B,MCMBP,PRR5L,RPS6KA2,CSRNP3,ATXN2,HOGA1,SCP2,SEC14L1,CASC3,TRA2B,KIF21A,ITSN1,SH3GL3,FERMT1,CHD9,FBXO11,DZIP1,PKNOX2,SIRT2,SLC14A1,BTBD7,SLIT1,MBD5,CABCOCO1,USP33,UHRF1BP1L,CDK19,SRPK2,CLSTN2,NKAIN2,NXT2,DIP2A,GSE1,NSFL1C,KLHL7,NECAB1,ARHGEF9,SYN2,ANKRD28,UNC5D,ADGRL3,ZFP90,TCF7L2,TCF12,DOCK9,OBSL1,FRYL,SIRT1,ZFPM2,LEFTY2,HHIP,ARL10,ACTR6,TLR4,ERCC6L2,R3HDM1,CSMD1,TPM1,NPL,DOK6,SMUG1,NTSR2,TSC1,ANO5,UBE3A,LINC00689,UGT8,NSD2,ZBTB14,ZNF711,ZNF24,ZNF74,LYPD6,ZBTB38,TMEM237,PLPPR5,SMARCAD1,EMSY,CADM2,PCDH15,SLC17A6,PDSS2,EPM2A,JMJD1C,KLHDC1,NETO1,GAN,LAS1L,SENP7" MicroRNA hsa-miR-1278:mirSVR_lowEffct hsa-miR-1278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.54E-116 1.43E-112 2.14E-115 1.98E-114 328 1493 "CLK4,CSMD2,CSMD3,FMNL2,SLITRK1,ADD1,ADD3,PWWP2A,ADRA1D,DPY19L2P4,MTUS1,KCTD16,MARCH4,PCDH10,BBOX1,GPRASP2,PITPNM2,ZFAT,FGD2,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,DGKD,PPFIA3,SHTN1,SHROOM2,TMEM263,CDK13,DDX3Y,ALDH7A1,ADAM23,RGS9,KSR1,ARHGEF7,BTK,CASTOR3,OSGIN2,RAB29,CALB1,PRC1,CDH2,CDH8,CDH18,NOG,KIAA1549L,TJP2,FAM19A5,DNAJB5,SULT4A1,MAP4K4,TMEM155,IGLON5,CNR1,PCYT1B,AKAP6,MYRIP,CREM,SH2B1,SNCAIP,CSF1,MICAL2,CSNK1G3,SOCS5,FAM169A,ARHGEF4,ECE2,KIAA0408,DCAF8,ZFYVE16,LONRF1,MATR3,IST1,DGKB,TOMM20,PABPC5,C8orf34,ZEB2,HEPH,KIAA0319,CEP170,DDX46,PLPPR4,G3BP2,RABGAP1L,KIF19,DLG2,RAB39B,DMD,HS3ST2,DNAJB6,DYRK1A,E2F6,MBNL2,EGR3,ASB3,IRAK4,COPS4,ELN,PAN3,RCAN2,GPHN,MRVI1,FKTN,SEC24B,SPSB4,SYNCRIP,RGPD5,FOXO3,SLC37A3,PDLIM5,ATP2C1,STAU2,SARAF,DOT1L,OGA,ZMAT1,GAB1,GABRA2,B4GALNT1,ERAP1,DISC1,GCNT2,SESN1,ADAM28,CSDC2,TXNL4A,GLDC,GNAS,CNDP1,TDRKH,FUT10,GPR22,MCHR1,NUDT21,GPR37,CECR2,DIDO1,GRIA4,ADAMTS8,NR3C1,GRM1,GRM7,BTN2A1,LINC01551,AP4S1,PSIP1,WIF1,ZHX1,ARHGAP36,ELOVL5,HNRNPK,NEGR1,AGFG1,HSF2,LRRCC1,USP54,LIX1,NME9,KCNA4,KCNA6,KCND2,KCNK2,KIF5C,KLRC2,STMN1,SMAD1,GPR155,MARK1,LRP1B,SRSF12,KCTD6,SCAMP5,MN1,WDR49,SESN3,CCDC80,MSR1,MSRA,C10orf105,MYCN,MYO7A,NCAM1,NELL2,NF1,ALDH1L2,CNOT4,DNHD1,SLC11A2,SMIM11A,HCN1,TBC1D25,LOC100128398,P2RX7,PAK3,PBX1,PCDH8,PCDH9,PDYN,CDK14,ZNF655,CCSER2,XRN1,MAPKAP1,LRP12,PPM1B,PPP2R5C,PPP2R5E,PPP3CB,MAPK7,HYDIN,GON4L,PLPPR1,PTHLH,TMEM260,ZSCAN32,PTPRE,ZNF493,RASGRF2,ARID4A,SLC6A15,GTDC1,ZDHHC4,RIC8B,RPRD1A,ZFHX4,CCDC82,CARF,CCDC102B,RPE65,BAALC,ACER3,KCNIP3,CCDC112,RMI1,ATXN2,SCN3A,LRRTM4,ELMOD1,SEC14L1,GALNT10,FOXRED1,NTNG1,MAGI3,WDR47,RUFY2,SLC6A1,KANSL3,PKNOX2,SCMH1,BTBD7,SPHKAP,SMARCA4,SMARCE1,RIMS1,SNAP25,PDZD2,MYT1L,BDP1,ENKUR,TEX2,ZNF423,ZC3H13,ZBTB43,RBM26,NFASC,C11orf87,EPB41L3,SULF2,AJAP1,FGD4,ARHGEF9,COBL,ANKRD12,CAMTA1,UNC5D,TBCEL,ANO4,EHBP1,ACSL6,DMXL2,ZEB1,DOCK9,RALYL,PCDHB3,FRYL,PMS2CL,ZFPM2,CRB1,AP4E1,ZNF106,TIE1,TMEM9,ERCC6L2,FAM124A,TPD52,SMUG1,PDSS1,RUNDC3B,STXBP4,TRPS1,KCNE5,TMEFF2,CADM1,DNAJC12,USP1,TBC1D15,RICTOR,GUSBP1,XPO1,PCDH20,GPR158-AS1,LYPD6,STOX2,HPS4,NAV3,FAM47E,WIPF2,RGS7BP,FAM13C,DOCK8,ST7,KAT6A,PHTF2,TIGD6,FXR1,IFT88,SLC4A10" MicroRNA hsa-miR-3129:mirSVR_lowEffct hsa-miR-3129:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.83E-116 1.59E-112 2.38E-115 2.19E-114 330 1511 "ACADM,AS3MT,SLC12A5,PLEKHH1,BEND6,INTS2,HECW2,OSBPL1A,TBC1D14,WDR35,CC2D2A,HFM1,SEMA6A,ARHGAP20,FAM135A,SYT13,AMPD2,ZFAT,LCORL,APBB2,LRRC4C,API5,USP37,MIER1,TMEFF1,ZFYVE28,ARNTL,NUMB,ATP2B1,N4BP2L1,TTLL9,CFLAR,CDK5R1,CACNB4,CALB1,VXN,PRC1,CBFA2T2,ARHGEF2,REPS2,CDC42,LOC730101,CCPG1,NOG,NUMBL,CHRNB2,CNOT8,JAM2,NDST3,NRXN3,PLAA,PPT2,CLCN3,C4orf33,SLC4A8,MAGED1,RCHY1,ACBD5,ZFP28,HS3ST5,CDC42BPB,RBM39,AKAP12,ARHGEF10,MICAL2,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,SEC14L5,CCDC144A,HDAC9,TOX,TBC1D5,TMEM170A,DAPK1,TOMM20,GIT2,ARMCX2,KLHL3,PLPPR4,AK5,SLC29A4,ABI1,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,YAF2,CELSR3,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,EPHB1,ENPP6,GPHN,ERBB4,MRPL37,PIPOX,F5,FAM198B,FABP7,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,SYNCRIP,RGPD5,FOXM1,FLT1,ANKFY1,FAM49B,ATP6V1H,ATP2C1,KHDRBS3,NSG1,MPP6,GABRA1,ILDR2,HBS1L,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GLS,GNAL,GNAS,LNX1,GOLGB1,PRUNE2,TPPP,GRB10,GRIA1,GRM5,KAT7,ZBTB49,FAM222A,CELF3,IRAK3,FRMD5,ARHGAP19,BACH2,AGBL5,C5orf24,IGFBP1,KCND2,KCNH1,KCNK1,KIF5C,IPO5,STXBP5,CYP27C1,ZFYVE27,MAPT,MBD1,SYT9,LRP1B,MEF2C,MEIS1,PPM1L,AFDN,ZNF680,BCO1,LYRM9,LAYN,P2RY13,ZC3H12B,NEUROD1,SLCO1C1,NFYA,NTRK2,SETD4,ODF2,OPA1,GPR137C,CCSER2,ZFYVE21,PKM,FAM216A,PLP1,HMGCLL1,STRN3,SPATA6,PPM1B,TATDN3,PPP3CA,PPP3CB,PRKACB,MAPK4,HYDIN,DIRAS2,VPS13C,WDR25,PIGG,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,TUG1,FAM184A,RDX,DPF2,RFX2,RFX4,RGS3,ARHGEF10L,SLC25A36,TMLHE,EXD2,KLHDC8A,ROBO2,CCDC25,ELP2,RPL15,SPIN3,TCP11L1,RPS6KA2,LGR4,ABCA11P,ATXN7,FAM19A1,TNFRSF19,TRIM46,TRA2B,SCAF8,ITSN1,PPP1R9A,MYO18A,SHC4,FBXO11,CCDC92,NLGN1,PAAF1,PEX26,RAB3GAP1,CCDC88A,SLC12A2,SLIT1,SORCS3,FAIM2,UNC80,KDM4B,TNIK,BDP1,RBM26,SPART,NFASC,ATP10B,ITPRID2,STOX1,SSTR1,STAU1,ADHFE1,KLHL7,C3orf70,SYT4,DNMBP,FAM208A,ADGRL3,FBXW11,ZEB1,TRIM2,DOCK9,RALYL,ARHGEF12,ATP13A2,DNAH7,DICER1,DICER1-AS1,ZFPM2,C18orf54,ITGB3BP,ZNF106,AKTIP,CDH22,NACC2,TJP1,RIMBP2,PRMT8,TMPRSS5,TTC3,HEPACAM,AMOT,DNAJC12,USP1,BEST1,CFAP298,PCDH20,ZFP37,ZBTB14,ZIC3,SLC26A10,LYPD6,WNK1,PRDM2,SLC38A1,PRDM10,HPS4,PCDH15,NAV3,NAV2,FAM47E,DNAH10,FZD3,PAK5,HNRNPA3,PHTF2,TIGD6,MSRB3,PIANP,SOCS4" MicroRNA hsa-miR-299-5p:mirSVR_lowEffct hsa-miR-299-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.61E-116 2.03E-112 3.04E-115 2.80E-114 331 1521 "DGCR6,KCNH8,KDM5D,ARID1A,SLITRK1,CCDC85A,AXIN2,BRAP,CDC7,PWWP2A,KIDINS220,BEND6,INTS2,GPR158,RTL9,HFM1,C1QTNF1,SEMA6A,FAM135A,AMPH,ANK3,LCORL,USP28,PPFIA1,APC,GAS7,CACHD1,SHTN1,CDK10,SPTBN4,ARHGAP5,DACT3,BRINP2,ATM,ATP2A2,ATP2B1,SLC2A11,NOL4,ADAM23,ADGRB3,GPC2,WASF1,KALRN,PTBP2,CAST,LDB2,CCNH,TMEM257,CDH2,LRRFIP1,LGI1,MAGI1,DLGAP1,TBRG4,FOXN3,SOCS6,CHM,CHN1,RAB28,MAP4K4,NIPBL,CNGA3,PCYT1B,COL4A5,LETMD1,GAL3ST1,AHCTF1,HS3ST5,SLC35F1,ENTPD4,RNF14,GDA,CS,SNCAIP,CSF3R,LRRC3B,ARHGEF10,CSNK1E,CFAP61,USP6NL,ARHGAP24,HDAC4,DGKB,IP6K1,CTIF,DNAL1,DCC,ELMSAN1,MYEF2,KIAA0753,CEP170,SMG7,SNAP91,SV2B,SPOCK3,DMD,ABI1,DYRK1A,E2F5,ATL1,TMTC1,SUGP2,MBNL2,RASA4,ASB3,PLEKHA1,EIF1,EPHA5,EPHB1,RABEPK,TMEM74,CDKL3,TLR7,ABCA8,ZNF585B,TAOK3,CHST15,KIAA1109,FGF1,FGFR1,FHL1,POLK,UBE2E3,CAP2,RGPD5,SGIP1,SLC37A3,NELFCD,COQ5,EFCAB2,NPTN,ATP2C1,CELF1,CSPG5,HHIPL1,STAG2,DKK3,GAB1,GABRB3,GABRG1,GAD2,RAPGEF6,ERAP1,ATP8A2,ALDH1L1,MSTN,BRD8,COPS8,SPIN1,TNRC6A,CBX1,GPM6B,LILRA1,DIDO1,GRIN2C,HAS2,FRMD5,HMGB1,HMGCR,ZDHHC15,CELF5,IDH3A,DOCK7,KCNA1,KCNJ10,STXBP5,LIG4,SYTL4,HECTD2,SMAD1,MAP2,MARK1,CHIC1,MEST,POC1B,AFF1,AFDN,MOBP,BLOC1S2,ADAM22,MYO9A,NAP1L3,ZC3H12B,NDUFA5,NEUROD1,NFE2L2,NOVA1,NTRK2,OMG,OPA1,ZDHHC22,GLIPR1L2,CNTN3,PCMT1,PCSK2,PRTG,PDGFRA,PDPK1,PENK,OLA1,ANLN,ZNF655,FAM218A,JAKMIP1,PCDH18,SMIM7,PURG,STRN3,EXOSC10,SPATA6,PPM1B,PKIA,MAPK9,DCHS2,MDGA2,UHRF1BP1,MTMR10,PTHLH,SPDL1,PTN,ZSCAN32,ZNF844,PPP2R3C,CCDC40,RAP1GDS1,OXR1,RBBP6,HKR1,KHDRBS2,MSANTD2,RDX,RFX4,TTLL7,RNF220,ZNF532,TMLHE,CARF,PRR5L,ACER3,WLS,SEMA6D,LRRTM4,SCP2,SEC14L1,SCAF8,SHC4,FBXO11,BCAN,NLGN1,DZIP1,PAAF1,BTBD3,SLC8A1,SLC12A2,ATF7IP,ZNF667,SMARCA4,DMRTC1,MYH15,RCOR3,RIMS1,MYO16,BDP1,MYCBP2,RBM26,TROVE2,CLSTN2,EPB41L3,ZSCAN29,CEP68,GANAB,ACSBG1,ZC3H4,SYNE2,ASTN2,TAF9,TAL1,ADGRL3,KIAA1107,MGRN1,TBX15,TCF4,TCF7L2,OBSL1,NSD1,SIK3,DNAH7,DICER1-AS1,ZFPM2,TIAM1,R3HDM1,CSMD1,TPM1,NPL,TPM3,WBP2,DOK6,RGMB,NR2C2,SYNPO2,PDSS1,HSPBP1,UGT8,PLEKHH2,VLDLR,WIPF1,P2RY12,NSD2,ETNPPL,XPO1,PCDH20,ZNF711,ZNF45,LYPD6,ZNF189,ANKS1B,WNK1,CADM2,LINC02210,ADAMTS9,PCDH15,GOPC,FAM13C,FZD3,MARCH8,RTN4,PAK5,PHTF2,FBXO36,SLC39A12,KLHDC1" MicroRNA hsa-miR-625:mirSVR_highEffct hsa-miR-625:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.06E-116 2.28E-112 3.41E-115 3.14E-114 269 1012 "ABCF1,ACHE,ACLY,ACTN2,ARID1A,CSMD3,NDRG2,DSCAML1,AXIN2,PLEKHH1,GRAMD1B,PTCHD1,ADRB2,HECW2,KLHL13,PCDH19,WDR35,CC2D2A,SEMA6A,LTBP4,ANK2,PPFIA1,CNTNAP1,UPRT,LGR5,SHROOM2,ARNTL,ASPH,PCDHGB4,RASL11B,BACH1,BCHE,BCL7A,GPR146,FUBP1,CASTOR3,JAZF1,C5,WASF1,CACNA1D,DDR1,KALRN,TRIM41,SPAG9,ZNF501,INA,CBFA2T2,LRBA,DCLK1,CDH18,CACNA2D2,CFL2,PLEKHB1,SYNPR,NRXN3,ZFYVE9,PPT2,TPP1,QKI,NIPBL,PICK1,CNTN1,BTF3L4,LETMD1,AHCTF1,SMARCAL1,TOGARAM2,CRMP1,CRYBB1,CLIP3,SNCAIP,OSBPL3,PLXNA4,FAM169A,APPL1,CTNND1,CTNND2,ST18,EDRF1,CCDC144A,KATNAL2,ELMSAN1,DNAJC6,ZEB2,MYEF2,CEP170,G3BP2,WDR20,CCDC3,CHRDL1,EXOG,SLC12A6,DPH1,DTNA,DTNB,DUSP9,DYRK1A,EDN1,KMT5B,ELAVL2,ING4,TNK2,DCTN4,EMX2,RCAN2,MTSS1L,CDKL3,CLVS1,FGF1,DCTN2,ST6GALNAC3,MSANTD4,ZNF512,GABBR1,GABRA3,GAD2,JPH4,IP6K3,DISC1,TUBA8,SPIN1,GLI2,PCDH11X,CCDC184,ATP2B1-AS1,C1QL4,GRIA4,GRIK2,GRM3,PSIP1,FAM222A,NXPH2,PTGDR2,ATXN2L,ARHGAP36,ACOT7,AGBL5,HNRNPK,ZDHHC15,DHX35,LRRC75A,C5orf24,USP54,KCNMA1,KIF5C,KIT,INSYN2,ADAM11,IL17D,SCG3,RSPO2,P2RY13,NDP,NDUFA5,NOS1,NTRK3,CLDN11,PCDHGC3,SERPINE2,PKM,PLCB2,PLP1,PURG,EPB41L4B,POLR2F,POU3F2,IRX1,PPP2R2C,MAPK9,HYDIN,MASP1,VPS13C,SIDT1,CNTLN,ELOVL2,TMEM260,OCIAD1,PTPRO,PEX5,RAB5B,RAD51D,FAM66C,ATG16L1,SUSD4,BSDC1,GAL3ST4,GTDC1,UBR7,SLC25A36,SETD5,CARF,TCP11L1,ATAT1,KCNIP2,RTN1,LINC00461,ITSN1,PPM1E,ST3GAL3,ZNF365,PPP4R3A,SLC8A3,SIRT2,ELMO2,EFHD1,ANKFN1,SOX2,ZNF423,SPTAN1,ATP10B,INKA2,SEPT8,RGL1,GANAB,PRRC2C,ARHGEF9,VPS13A,KAZN,MTCL1,ADGRL3,ATMIN,EHBP1,TCF7L2,TRIM2,TCF12,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RNF216P1,C18orf54,ITGB3BP,LEFTY2,TGFBR3,CDH22,CSMD1,ELP5,ZMYND8,TTC3,CADM1,AMOT,UGT8,FLRT1,BEST1,TBC1D15,VSNL1,ZNF32,KCNT2,AGMO,MKRN3,CELF4,REEP1,ZSCAN26,PLPPR5,CA10,CADM2,ST7,TIGD6,PIANP" MicroRNA hsa-miR-135a-5p:TargetScan hsa-miR-135a-5p TargetScan 5.64E-116 3.17E-112 4.72E-115 4.35E-114 211 609 "DPF1,ABAT,ADARB2,GALNT13,ADCYAP1R1,INTS2,MTUS1,GPR158,ALCAM,ANK3,ANXA7,CNTNAP1,APC,GAS7,ARNTL,PDE8B,ASPH,NCOA1,DDX3Y,ATP2B2,ATP2B3,CADM3,BACH1,BCL2L2,HCN2,DST,ARHGEF7,MTMR2,BSN,LDLRAD4,BTRC,FOXK1,CACNA1D,CACNA1E,PTBP2,CAMK2D,LDB2,ARHGEF2,KCNAB3,DCLK1,LRRFIP1,DLGAP2,FOXN3,CLCN3,QKI,RAB26,ARHGEF6,PCYT1B,BAG4,C2CD2,ENTPD4,CSF1,CSNK1G3,ATRNL1,ERC2,PLCXD3,ARHGEF4,NRSN1,RIMS2,NOS1AP,ARHGAP32,FRMPD4,HDAC4,PHF19,LONRF1,KIAA0087,DNAL1,PITPNC1,ELMSAN1,JAKMIP2,PLEKHM1,MYEF2,CEP170,DLG2,RAB39B,CALN1,DTNA,EBF1,HIPK3,ABI2,ERBB4,CEP85L,DNAJC27,EXTL2,EYA1,CACNG2,SCML2,ATP8A1,FGF11,CAP2,NBEA,NSG1,FUT9,MEGF11,GABRA5,GABRB1,ILDR2,DENND2A,AHCYL1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,FAXC,GCNT2,GHR,GNG3,FERMT2,CNDP1,PRUNE2,GPM6B,DIDO1,GRIK3,PTPRT,PSIP1,GUCY1A2,RASSF8,HPS5,ARHGAP19,NEGR1,IL6ST,ITGAV,JAK2,KCNB1,KCNC2,KCND1,CLVS2,KCNJ3,KCNN3,KCNQ3,GPR155,MAP4,MBNL1,MDM4,MEF2C,MMP16,MYO9A,NEFM,NF1,NPTX1,HCN1,ODF2,PCDH9,PDE1C,PDE3B,PDE4A,GDAP1L1,CCSER2,FTO,DRAM2,MED1,PPP2R5C,MAPK10,DIRAS2,GDPD1,ELOVL2,PTK2,PTPRD,RAB5B,RAP1GDS1,ERI2,PRIMA1,RAVER2,ROBO1,RORB,PCMTD2,RIMKLA,ATXN1,SCN2A,SCN2B,SEC14L1,MRAS,HSPA4L,PPM1E,NTNG1,FAM81A,RIMS1,MAPKBP1,FAM126B,MYT1L,IQSEC2,NXT2,RGL1,GSE1,PRRC2C,DNAJC9,PLCB1,ARC,ANO4,CUX2,CLASP1,PSD3,C18orf54,FBXL16,MTMR14,CSMD1,KAT6B,RBFOX2,FNDC5,ANO5,CADM1,KCNK12,NDRG4,EVI5,ADAMTS9,HNRNPA3,CAMK1G,ACTR3B,MSRB3,NETO2,LAS1L" MicroRNA hsa-miR-135b-5p:TargetScan hsa-miR-135b-5p TargetScan 5.64E-116 3.17E-112 4.72E-115 4.35E-114 211 609 "DPF1,ABAT,ADARB2,GALNT13,ADCYAP1R1,INTS2,MTUS1,GPR158,ALCAM,ANK3,ANXA7,CNTNAP1,APC,GAS7,ARNTL,PDE8B,ASPH,NCOA1,DDX3Y,ATP2B2,ATP2B3,CADM3,BACH1,BCL2L2,HCN2,DST,ARHGEF7,MTMR2,BSN,LDLRAD4,BTRC,FOXK1,CACNA1D,CACNA1E,PTBP2,CAMK2D,LDB2,ARHGEF2,KCNAB3,DCLK1,LRRFIP1,DLGAP2,FOXN3,CLCN3,QKI,RAB26,ARHGEF6,PCYT1B,BAG4,C2CD2,ENTPD4,CSF1,CSNK1G3,ATRNL1,ERC2,PLCXD3,ARHGEF4,NRSN1,RIMS2,NOS1AP,ARHGAP32,FRMPD4,HDAC4,PHF19,LONRF1,KIAA0087,DNAL1,PITPNC1,ELMSAN1,JAKMIP2,PLEKHM1,MYEF2,CEP170,DLG2,RAB39B,CALN1,DTNA,EBF1,HIPK3,ABI2,ERBB4,CEP85L,DNAJC27,EXTL2,EYA1,CACNG2,SCML2,ATP8A1,FGF11,CAP2,NBEA,NSG1,FUT9,MEGF11,GABRA5,GABRB1,ILDR2,DENND2A,AHCYL1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,FAXC,GCNT2,GHR,GNG3,FERMT2,CNDP1,PRUNE2,GPM6B,DIDO1,GRIK3,PTPRT,PSIP1,GUCY1A2,RASSF8,HPS5,ARHGAP19,NEGR1,IL6ST,ITGAV,JAK2,KCNB1,KCNC2,KCND1,CLVS2,KCNJ3,KCNN3,KCNQ3,GPR155,MAP4,MBNL1,MDM4,MEF2C,MMP16,MYO9A,NEFM,NF1,NPTX1,HCN1,ODF2,PCDH9,PDE1C,PDE3B,PDE4A,GDAP1L1,CCSER2,FTO,DRAM2,MED1,PPP2R5C,MAPK10,DIRAS2,GDPD1,ELOVL2,PTK2,PTPRD,RAB5B,RAP1GDS1,ERI2,PRIMA1,RAVER2,ROBO1,RORB,PCMTD2,RIMKLA,ATXN1,SCN2A,SCN2B,SEC14L1,MRAS,HSPA4L,PPM1E,NTNG1,FAM81A,RIMS1,MAPKBP1,FAM126B,MYT1L,IQSEC2,NXT2,RGL1,GSE1,PRRC2C,DNAJC9,PLCB1,ARC,ANO4,CUX2,CLASP1,PSD3,C18orf54,FBXL16,MTMR14,CSMD1,KAT6B,RBFOX2,FNDC5,ANO5,CADM1,KCNK12,NDRG4,EVI5,ADAMTS9,HNRNPA3,CAMK1G,ACTR3B,MSRB3,NETO2,LAS1L" MicroRNA hsa-miR-193b:mirSVR_lowEffct hsa-miR-193b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.71E-116 3.21E-112 4.77E-115 4.39E-114 291 1186 "KCNH8,ACADM,ASIC1,ACHE,CLK4,NCKAP5,ADCY6,ADD1,SORCS1,PWWP2A,PTCHD1,KIDINS220,SLC24A4,AP2A2,DISP3,PCDH10,UNC79,ANK3,APC,VAT1L,BCAS1,TNRC6C,APP,CDK10,SEMA4G,PDXK,CASK,ZSCAN18,EIF4G3,DPY19L3,BCL2L2,SYNJ1,SYNJ2,JAZF1,C1QC,CAST,P2RX6,LRBA,EVI5L,NOG,UBE2L6,CACNA2D2,CASC2,TAOK2,EPS15L1,NRXN3,KIAA1549L,CLTC,TJP2,ARHGEF6,AKAP6,TOGARAM2,CHD1L,NCOR1,FEZ1,CST3,PLXNA4,PPP1R16B,NRSN1,RUBCN,FAM131B,CX3CR1,ECE2,NOS1AP,FRMPD4,TM9SF4,ARMCX2,RUSC2,GUCD1,MTX3,NYAP1,DOCK2,MAMLD1,DNAJB6,DYRK1A,ABCC5,EDN1,HEYL,RBM12,GPR61,KMT5B,ABI2,GOLGA7,ASB3,EIF4G2,BSCL2,EN2,ETV1,SIRPB1,ADGRV1,F5,SCML2,FCGRT,TESK2,OLFM1,SEMA6C,ANKFY1,PSD2,EFCAB2,NSG2,GABBR1,TRAF3IP2,HBS1L,BRPF3,ZNF274,GAP43,ERAP1,CRCP,TCERG1,STARD3,NUDT21,RFFL,GRIN2C,PRDM5,GRM7,LINC01089,AP4S1,MAP4K5,MAEL,PADI2,ZHX1,MIER3,HMGB1,SMAP1,ICA1,MSL1,ZNF546,IL11RA,DIPK1A,INPP5B,ZNF385B,ITGAM,JAK2,KCNJ9,KCNK3,KIT,CAMK2N2,C2orf80,ASPRV1,ZFYVE27,IL17D,MGAT3,MMP16,ZNF680,CCDC80,RTL5,HNRNPM,NAP1L1,NCAM1,SLCO1C1,NNAT,NODAL,VWA2,DNHD1,NUMA1,OGG1,OMG,PCDH9,PCSK2,PDE4D,PDGFRA,PDPK1,PDYN,NALCN,CAMKV,CCSER2,NLE1,FAM216A,PLCB2,PNMA3,C11orf49,RETREG2,EPB41L4B,NXPH1,POU6F1,TATDN3,CCDC144B,PRKACB,PRKCZ,GRAMD1C,SLC22A23,SNRK,TMEM104,PTCH1,UHRF1BP1,PTHLH,PTK2,TMEM260,PTPRE,PTPRG,PTX3,CEP97,FAM66C,ZYG11B,TRIM68,SLC25A36,PBRM1,RNASEL,RNH1,GSTCD,KIRREL1,ROBO2,ATP8B4,ACER3,TCP11L1,RTKN,CLIP1,SATB1,GALNT10,ITSN1,SHMT2,NLGN1,SEC31A,CLSTN1,ZNF365,RUFY2,LRRC55,YPEL4,CCDC88A,ATF7IP,LIMCH1,PDZRN3,UNC80,USP33,DOP1A,WDTC1,SOX5,ZSWIM8,HECW1,UHRF1BP1L,TSPYL2,NPAS3,DDN,NFASC,SRPK2,TAB2,CLASP2,CLSTN2,SS18,MAPK8IP3,ZSCAN29,SEPT8,KANK1,NSFL1C,FGD4,SYN1,TMEM150C,COBL,ATP11A,TAF6,CNTN2,TMEM136,SMG6,TBX15,EHBP1,TCF4,PHF24,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,CRB1,TGFBR3,CDH22,TK2,LRRC8A,DAAM2,NPL,TPM2,ZNF346,AMACR,TRO,FNDC5,KCNE5,LRTM2,VLDLR,CLIP2,CRB2,WNK1,NT5M,RGMA,CSDE1,PRDM8,RNF103,NAV3,DOCK8,FXR1" MicroRNA hsa-miR-26a-1*:mirSVR_highEffct hsa-miR-26a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.37E-116 3.58E-112 5.32E-115 4.90E-114 314 1377 "CPNE2,ACADM,NCKAP5,NBAT1,ACTN2,KDM5D,XKR4,FMNL2,SORCS1,PLEKHH1,GRAMD1B,ADRA1D,BEND6,INTS2,HACE1,OSBPL1A,OSBPL8,CC2D2A,TAOK1,ADGRF5,C1QTNF3,ALCAM,FAM135A,ALK,OGT,DPP10,LRCH2,USP28,CASK,TMEFF1,ARNTL,ZBTB10,DDX3Y,DYNLL1,ATM,ATP1A1,SLC4A4,ATP2B1,ATP2B3,RNF182,ADGRB3,BBS2,BID,CFLAR,DST,RAB29,CACNA1D,CACNA1E,KALRN,CAMK2D,C1orf52,ABCG2,QKI,ARMC8,AHCTF1,ZFP28,CHD1L,ZNF385A,SLC35F1,CREM,ARHGEF10,ATRNL1,NCAN,PDE4DIP,DZIP3,ERC2,PHF14,CTNND2,PUM1,USP6NL,HDAC9,DCAF8,KCTD8,DAPK1,PABPC5,BRINP1,DCC,C8orf34,ZEB2,FBXL5,KBTBD11,CHRDL1,DLG2,EXOG,GRIN3A,DMD,NR1D2,DMTF1,DPYSL2,ECM2,ABCC5,DNM1L,GOLT1B,ANKRD46,RASGRP1,PHF20L1,SUGP2,AASS,PLEKHA1,C8orf37,CALCRL,KCNMB2,RABEPK,RTN3,EXTL1,ADGRV1,CLVS1,FAM198B,ACSL4,SCML2,ATP8A1,CEP78,FCGR3A,FER,SYNCRIP,ST6GALNAC3,GABRA5,GABRG2,TRAF3IP2,GAD1,FAM120B,ZMYND11,ERAP1,DISC1,GCNT2,SULT1C4,WASHC2A,MALT1,TCERG1,HPGDS,GLYR1,GLUL,PCDH11X,ZNF638,ZNF782,GPD2,PRLHR,GRIA4,GRIN2C,GRM7,FAM19A2,RNF165,ADAMTS6,RASSF8,NXPH2,HSP90AA1,EID2B,SOWAHA,DOCK7,USP54,IL12A,ZNF678,SLC35G1,KCND2,KIF5A,KLRC2,LMO2,LSAMP,LOC100128239,MAOB,MARK1,MDM4,MEF2C,SRSF12,MRPL42,NRBP2,SCG3,NAP1L1,NAP1L2,NCAM1,NEK1,NF1,SLC11A2,NRCAM,HCN1,IGSF11,OCRL,CHAMP1,OLR1,OPCML,OPHN1,PCMT1,PCSK5,PDE4D,PFKFB2,OLA1,PIK3C2A,FAM218A,XRN1,FAM216A,PLP1,HMGCLL1,PRIMPOL,PRRX1,SLC36A4,SH3KBP1,MINDY2,CRLS1,RANBP3L,GRAMD1C,HYDIN,DIRAS2,DCHS2,SNRK,PIGG,ANKHD1,TMEM260,USP47,FAM66C,SH3TC2,ENOX1,KHDRBS2,MSANTD2,CRTAC1,ERI2,RGS4,RGS12,RIC8B,RPRD1A,CARF,ROBO2,CCDC102B,LRRK2,MEG3,ZNF568,ZNF331,SCN2A,SCN3A,SOX6,SCAF8,NTNG1,MAGI3,CHD9,FBXO11,CTXN2,NUBPL,SLC1A3,SLC8A1,EFHD1,SLC20A2,SLCO1A2,ZNF667,SMARCE1,ANKRD36,SNCA,MBD5,SNRPN,UNC80,MYT1L,SP4,CLUAP1,PEG10,RBM26,LMO3,SRPK2,ATP10B,TROVE2,SSTR2,NKAIN2,NXT2,DIP2A,SULF2,KLHL7,SUPT5H,SYNE2,VPS13A,TMEM150C,SYT1,ANKRD28,TACR1,CAMSAP2,TBX15,WSCD1,TCF4,SATB2,TRIM2,DOCK9,SLC19A3,PCDHB7,PCDHB3,NSD1,GPRIN3,FRYL,SIRT1,ITGB3BP,TNS1,TPD52,CDK20,RGMB,SYNPO2,METTL3,ELP5,TRIO,ANO5,ZNF610,FLRT1,CCDC14,WIPF1,XPO1,ZBTB14,CELF4,TMEM237,FSTL5,ZNF184,EML6,ANKS1B,SLC30A4,SLC17A6,C12orf4,EPM2A,SMIM8,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-144*:mirSVR_lowEffct hsa-miR-144*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.53E-116 4.23E-112 6.27E-115 5.78E-114 326 1481 "RALGAPA1,SDE2,ACTN1,CSMD3,GALNT13,SORCS1,ADORA3,PTCHD1,HECW2,OSBPL1A,OSBPL8,TAOK1,SMIM17,BCAR3,SUGT1P4-STRA6LP-CCDC180,UPRT,GPAM,CACHD1,SHTN1,PPP4R4,ASPA,ASPH,NUMB,DPY19L3,DOCK11,SEC11C,CFLAR,DST,MTMR2,JAZF1,C1QC,WASF1,CACNA1B,CACNB2,THSD7A,BRSK2,RUNX1T1,USP6,DCLK1,COPB2,ADGRG1,B4GALT6,ZBED5,RAB28,NRXN3,KIAA1549L,QKI,FHL5,LETMD1,COL9A3,MAGED1,RCHY1,TBPL1,BAG4,CNRIP1,FAM171B,ANKRD44,IPCEF1,PPP1R16B,CTNND2,ZSCAN23,KIAA0586,DGKG,DAPK1,DNAL1,ZNF804A,ZEB2,TIAM2,KLHL3,BLOC1S6,PLPPR4,SACS,SRGAP3,NTM,WDR20,FAM107B,KBTBD11,DMD,CD99L2,CPEB2,CASP8AP2,DYRK1A,SEMA3D,PHF20L1,ABI2,RASA4,VPS13B,RABEPK,STX2,DENND4A,CDHR1,TMEM74,DNAJC27,SIRPB1,KATNAL1,NSRP1,SCML2,DLC1,FKTN,SEC24B,SLC9B2,KIAA1109,POLR1B,POLK,UBE2E3,MEX3B,SYNCRIP,EFCAB2,TRMO,NBEA,UFM1,FAM49B,NSG1,PNMA2,ZMAT1,DKK3,GAB1,TRAF3IP2,CAB39,HBS1L,BRPF3,ZMYND11,NCKAP1,ZNF559,DISC1,DNER,GATM,IGSF5,NFU1,ADAM28,PPARGC1A,GK,GLI2,RAB30,GLS,TOX3,ZNF638,HTATSF1,ADGRA3,STON1,GPR22,PCLO,STMN2,GRIA4,GRIN1,GRM1,BTN2A1,LINC00839,RNF165,TMEM25,HAS2,HLF,HMGB1,HNF4G,DHX35,HSF2,HTR2A,IDH3A,C5orf24,IGFBP1,IL6R,INSM1,KCNA2,KCNJ10,KCNK2,IPO5,STXBP5,PAXBP1,LMO2,MBNL1,MEIS1,KITLG,MID1,MN1,MRPL42,CCDC80,ZC3H12B,NEFM,NEK1,NEUROD1,NFE2L2,ALDH1L2,NPR2,NTRK2,OPA1,KCNK10,GLIPR1L2,ETFRF1,PCMT1,PDE3B,PDGFRA,ENPP2,PDPK1,PFKFB4,NLGN3,SSH1,PIK3R1,FAM216A,PLCB2,FTO,PLP1,MAPKAP1,FAT3,PPM1B,RANBP3L,PRKAB2,GON4L,CNTLN,UHRF1BP1,ZIK1,PTPRG,PTPRZ1,PPP2R3C,ZNF793,IQSEC3,FAT4,FAM184A,ENOX1,RBBP6,KHDRBS2,REV3L,TTLL7,SEC61A2,NUDT11,DCUN1D2,RAVER2,ROBO1,PCMTD2,MRAP2,NEK11,ARMH4,SPIN3,MCMBP,GLDN,ADAL,ACER3,MAP6D1,WLS,CCDC112,ATXN7,LRFN5,SCN3A,LRRTM4,FAM19A1,PRCD,SH3GL2,SH3GL3,KIF16B,CPEB3,ST6GAL1,CNKSR2,CTXN2,PREX2,SEPHS1,RAB3GAP1,TRIM67,SLC12A2,SLC14A1,SLCO1A2,SPHKAP,SLC22A4,ZFP1,SORCS3,ANKRD36,SNRPN,FAM126B,USP33,FAM219A,PDZD2,SOX2,BDP1,CAND2,HECW1,MYCBP2,SPTB,KIF1B,TAB2,ZNF621,ATP10B,NXT2,NCDN,STAU1,CEP68,KANK1,FGD4,VPS13A,COBL,ANKRD12,TBCEL,TCEA1,ACSL6,DMXL2,RPGRIP1L,SYNE1,RALYL,PCDHB4,SIK3,FAM200B,SIRT1,DICER1-AS1,HHIP,BEX4,TPM1,RGMB,PDSS1,TSN,SSBP2,UBE2H,WRN,TRIM9,ZNF154,EVI5,SCG2,PCDH15,HRASLS,FAM13C,PHTF2,FBXO36,JMJD1C,RNF170,MSRB3,FRMD6,NETO2,NETO1,RNF146,SLC4A10" MicroRNA hsa-miR-196b:mirSVR_lowEffct hsa-miR-196b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.59E-116 4.26E-112 6.31E-115 5.82E-114 297 1236 "ACTN1,GALNT16,TMCC3,GALNT13,USP31,ADRB2,KIDINS220,BEND6,SLC44A5,HECW2,PCDH19,OSBPL1A,KIAA1324,AK2,ALCAM,ARHGAP20,PCDH10,FAM135A,DOC2A,AMPD2,AMPD3,AMPH,EP400,LCORL,PPFIA2,LGR5,AQP4,TMEM263,IGDCC4,CASK,CDK13,ASCL1,ZBTB10,CHRD,TMEM108,ATP1B3,ATP2B1,TTLL9,BACH1,CFLAR,KSR1,GYG2,CACNB4,CAST,CCKBR,METTL6,CD86,DGKI,LRBA,SEPT7,ADGRG1,ASIC3,RAB3C,B4GALT6,NDST3,PLAA,COG1,TPP1,ABCG2,C4orf33,SRP14-AS1,LETMD1,SLC4A7,SLC4A8,AHCTF1,SMARCAL1,MFSD4A,CS,RGS6,VAC14-AS1,FAM169A,PPP1R16B,APPL1,UBXN2A,CFAP61,CTNND2,NRSN1,GAPVD1,FRMPD4,ZFYVE16,ELMSAN1,C8orf34,COPS7A,BLOC1S6,DLG2,SLC29A4,DOCK2,DMTF1,DSCAM,DTNA,ECM2,E2F5,AASDH,EBF1,FAM135B,HIPK3,RASGRP1,TMTC1,APH1A,ABI2,ASB3,EIF4G2,DCTN4,USPL1,EPB41,GPHN,RABEPK,SRRM1,ARMCX1,CHST15,ZNF589,POLR1B,SUCO,AGAP2,SYNCRIP,FOLR2,JKAMP,FAM49B,ARFGAP2,ATP6V1H,ZNF605,BRPF3,ARPP21,C15orf41,GATM,SULT1C4,PRRC2B,PRUNE2,CCDC184,CNTRL,RFFL,ADAMTS8,NR3C1,GRM5,RNFT2,MAEL,RASSF8,HAS2,ATXN2L,HMGB1,AGBL5,ZNF491,ZDHHC15,CELF5,FAM95B1,C2orf72,NKD1,IL11RA,LRRTM3,ITGAV,SLC35G1,KCNA1,KCNC2,KCNJ5,STXBP5,LRRC4B,ZFYVE27,MAT2A,MBD1,AFDN,BLOC1S2,MXI1,MYO6,NAP1L1,ZC3H12B,NDUFA5,NEUROD2,ALDH1L2,NME4,CNOT4,NOVA1,NPR2,IGSF11,OGG1,PBX1,ETFRF1,PCDH8,PCSK5,PDE2A,PDGFRA,PFKFB3,SERPINI1,CCSER2,PLCB2,HMGCLL1,PRKCZ,MAPK9,MASP1,LRRC49,GDPD2,MDGA2,PIGG,BDNF-AS,PTK2,PTPRB,TUG1,ZDHHC14,BSDC1,RDX,ZYG11B,RET,RFX4,CARF,PCMTD2,UEVLD,MCMBP,ACER3,CNTNAP3,LGR4,KCNIP3,WLS,CLIP1,MIR124-2HG,ELMOD1,SEC14L1,FOXRED1,COPZ1,CPEB3,FNDC3A,ANKRD6,DHX30,TRIM67,SLC20A2,SLCO1A2,MAST1,PDZRN3,MYO16,DOP1A,TNIK,SOX11,MYCBP2,KDM4C,PEG10,TSPYL2,LMO3,STOX1,LARP4,NCDN,CEP68,ADHFE1,ACSBG1,FGD4,SYNE2,VPS13A,SYP,COBL,ANKRD28,MTCL1,VWA3A,CUX2,TCF7,TPCN2,TRIM2,RPGRIP1L,WDR7,AZIN2,SYNE1,DOCK9,AKNA,TNS2,HIF3A,RNF216P1,DICER1,KHDC1,CRB1,TGFBR3,ZNF106,AKTIP,KCTD2,NPL,NR2C2,TUB,ZNF610,AMOT,UGT8,DNAJC12,FLRT1,WIPF1,NSD2,RICTOR,ETNPPL,XPO1,ZBTB14,ZNF24,KCNT2,FMN2,CELF4,PLPPR5,DHX33,WNK1,PRDM2,CSDE1,PCDH15,PARP11,PHTF2,SOCS4,JPH3" MicroRNA hsa-miR-197:mirSVR_lowEffct hsa-miR-197:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.46E-116 4.75E-112 7.03E-115 6.48E-114 343 1632 "SERPINA3,DGCR6,ACADM,ADCY6,UNC5A,ADORA3,SEMA6A,PCDH10,FAM135A,AMPD3,ZFAT,CDC42BPA,DPP10,ANK2,ANK3,FGD2,CNIH2,DGKZ,UPRT,PPFIA3,SEMA4G,PPP4R4,EIF4G3,RNF182,NOL4,ATP6V0A1,RIPK1,ADGRB3,MPDZ,CFLAR,KSR1,GYG2,CACNA1G,MMD2,CABP7,NGB,TRIM41,DGKI,LRBA,CDH2,CDH8,ZMYM4,LOC730101,CRLF1,RCBTB2,CHGA,JAM2,SULT4A1,SRP14-AS1,MAP4K4,AKAP7,AKAP6,ABI3BP,COX4I1,AHCTF1,SMARCAL1,MFSD4A,CHD1L,ANKRD44,GDA,FEZ2,ARHGEF10,SLITRK5,DZIP3,GREB1,RUBCN,GPRASP1,DCAF8,IST1,TMEM170A,TOMM20,DCC,KLHL3,DDX46,SMG7,SACS,SV2A,SRGAP3,KIF19,DNAH9,DOCK2,ACOT8,ATN1,RCAN1,MAMLD1,DYRK1A,ABCC5,DNM1L,EDN1,YAF2,APH1A,EGR3,RASA4,LPAR6,KCTD3,EIF4G2,ING4,DCTN4,RABEPK,SLC43A2,IGSF6,CDHR1,RCSD1,F3,RPS6KC1,EFEMP1,TOMM40L,FGFR1,BAIAP2,SYNCRIP,RGPD5,NELFCD,NBEA,SORBS1,NSG2,DACH2,SARAF,CHL1,GAD2,HBS1L,ZMYND11,GALC,NEK6,KIAA1841,GATM,SULT1C4,GFAP,GGT7,TOX3,MSL3,CBX1,DCLK2,LILRB4,GPM6B,NUDT21,GRB10,DIDO1,ADAMTS8,KIF3A,RNF165,GSTM5,AP4S1,MAP4K5,GYG1,PADI2,NXPH2,FRMD3,ARHGAP19,HLF,IDH3B,MYLK2,SCIN,INPP5B,LRRTM3,ITGAV,ITPKB,SLC35G1,METTL21A,KCND1,KCNJ9,KCNK2,KCNMA1,CREG2,LINC00634,HECTD2,MAP4,MAPT,MARK1,MBD1,MBNL1,IL17D,CHIC1,TM6SF1,MDM4,MIA2,MOBP,PTOV1,MT3,MX1,LYRM9,FXYD6,SFR1,NODAL,VWA2,NOS1,CNOT4,SLC11A2,HCN1,NTRK2,NUMA1,SETD4,OCRL,OPRL1,ZNF827,ZDHHC22,SNTG1,PAK3,PCMT1,PFKFB3,CAMKV,A2ML1,PLXNB1,PURG,ANKRD16,SCHIP1,MAGEL2,LRRN3,PPP3CA,PPP3CB,SLC26A11,PRPH,SAMD9,VPS13C,PIGG,PTCH1,BDNF-AS,ZIK1,EML5,PTPRG,PPP2R3C,GAL3ST4,ZYG11B,GTDC1,FIGN,RFX4,PBRM1,EXD2,ARMC5,CARF,ROBO2,SNX22,LGR4,SYNDIG1,ZNF568,ZNF331,RMI1,MAPK12,ATXN7,SCAF8,KIF21A,PPM1E,NTNG1,HKDC1,FBXO11,FHOD3,NUBPL,PAAF1,SLA,DHX30,FAM214B,LRRC55,SLC6A8,ZNF430,RAB3GAP1,SLC8A3,CDK5RAP3,SLC9A5,SLC12A2,TMEM132D,ATF7IP,SLC22A4,ZNF667,SORCS3,CDK5RAP2,LIMCH1,MBD5,SNRPN,FAM126B,MYO16,UNC80,SON,TNIK,BDP1,EMC1,SPP1,PEG10,TSPYL2,RBM26,NPAS3,ATP10B,CLSTN2,LRRC4,SSPO,MAPK8IP3,ZSCAN29,ELOVL4,STXBP1,ZC3H4,SUPT5H,DNAJC9,SYN1,SYN2,TAC1,DDHD2,EXOC7,TMEM136,ACSL6,TPCN2,TCF12,SZT2,AZIN2,ARHGAP9,CYB561A3,SPX,AP4E1,SLC44A1,TJP1,TLR4,TMOD1,C5orf64,TPD52L2,NPL,TPM2,STXBP4,NUTM2A,FNDC5,RUSC1,ZKSCAN5,TMEFF2,SLC35A4,BCL2L13,P2RY12,GUSBP1,LGI4,SLC47A2,TRIM9,NDRG4,MKRN3,ZNF138,AMZ1,EML6,ZXDA,PRDM2,RGMA,CIAPIN1,PPP1R3F,WNK3,MVB12B,GOPC,CERS6,TTC7A,IFT88,CPNE4" MicroRNA hsa-miR-92a-1*:mirSVR_lowEffct hsa-miR-92a-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.09E-116 5.10E-112 7.54E-115 6.94E-114 320 1430 "DGCR6,ABCF1,ACADM,ACHE,NCKAP5,XKR4,FMNL2,DSCAML1,SORCS1,PLEKHH1,GRAMD1B,UNC5A,ADORA3,SNX32,HECW2,MARCH4,ALK,DOC2A,OGT,ANK1,LCORL,CNIH2,APBB1,ALS2,FAM131A,TNRC6C,SFMBT2,RGS20,MARCH3,MARK4,CAPRIN2,PCDHGB4,NCOA1,ATP2B2,SLC2A11,B3GALT2,MPDZ,BMP7,SYNJ1,BTK,MYRF,BAIAP3,IL33,MMD2,CACNB4,KALRN,HAP1,PTBP2,TRIM41,CANX,CCK,USP2,ENTPD2,C1orf52,CDH8,ARHGAP33,SRSF11,CHRNB2,IGFBP7-AS1,NRXN2,NGEF,QKI,SULT4A1,IGLON5,CNR1,CNTN1,SLC25A27,ACBD5,HAPLN1,CRYBB1,MROH8,MICAL2,PLCH2,VAC14-AS1,FAM169A,CTH,ST18,ZNF337,ACY3,ARMCX4,C2CD2L,SV2A,SGSM2,DLG3,GRIN3A,DOCK2,DPH1,DRP2,RCAN1,AASDH,SEZ6L2,PHC2,APH1A,EGFR,MBNL2,ABI2,EGR3,C8orf37,ENO2,DMTN,ANKRD13B,IGSF6,ANKMY1,CEND1,ECSIT,CLVS1,TBC1D16,ACSL4,PTK2B,RACK1,TOMM40L,FKTN,BAIAP2,TMEM164,AGAP2,NOP56,SPECC1,FAM49B,TRIM16,NSG2,B3GAT1,HHIPL1,TPPP3,BRSK1,MEGF10,GABRA3,FAM184B,ZNF274,NCKAP1,LRRC37A6P,GCK,KIRREL3,GLI2,CCDC184,GPR17,PLPP7,RFFL,ADAMTS13,GRIN2D,PSIP1,SLC2A6,HPS5,HLF,SYNPO,SHISA6,FAM95B1,MYLK2,TJAP1,IGSF1,KCNC1,KCND2,KCNF1,KCNK3,KIF5A,MBD1,MDM4,KCTD6,PPM1L,MOBP,MOG,COL28A1,MYO7A,MYT1,NEK1,NOVA1,NRGN,IGSF11,OCRL,OGDH,OGG1,OLR1,ZNF827,ZDHHC22,SNTG1,PALM,PBX1,PCDHGC3,PCSK5,CDK18,PDE2A,PDE1B,PDGFRA,PFKFB4,PKM,PLEC,EPN1,PLP1,SLC25A23,PLTP,NECAB2,ING3,FA2H,POLR2F,FSD1,POU6F1,KLK6,CYBC1,CASTOR1,FAM66C,FAT4,RAP1GDS1,DUSP15,GTDC1,FIGN,ARHGEF10L,SLC25A36,LGI2,DCUN1D2,GLDN,SEMA6D,ATXN2,ATXN7,PRCD,PEAR1,SUPT20H,TRA2B,ITSN1,CCDC92,SLA,DHX30,KANSL3,SLC8A2,SLC8A1,TMEM132D,SLC22A4,SLN,CDK5RAP2,MBD5,PDZRN3,BDP1,KDM3A,ZSWIM8,NMNAT2,UNC5B,SPTAN1,SPTB,KIF1B,ATP10B,ZC4H2,MAPK8IP3,STAU1,STX1A,SEPT3,KLHL7,NECAB1,ZFR2,RHBDL3,SYN2,SYT5,TAC3,MLST8,EXOC7,PDLIM2,KLHL4,VWA3A,EHBP1,WSCD1,SIN3B,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,TMEM151B,PUM2,PMS2CL,AP4E1,TGFBR3,AKTIP,FBXL16,TMEM9,ZFP91,TMOD1,R3HDM1,CABIN1,CDK20,TPM2,C9orf85,ZNF384,SYNPO2,TRH,ELP5,AMACR,ANO5,TTTY15,ZKSCAN5,UBE2H,GORASP1,ATP6V0E2,SLC26A10,SPHK2,TCEAL7,ZNF138,ANKS1B,ZNF195,EMSY,NT5M,GDPD5,STOX2,LMAN2L,SEMA3B,NAV3,PPP1R3F,SNX27,TMEM163,TRIM16L,WIPF2,PAK5,PHTF2,LAS1L,JPH3" MicroRNA hsa-miR-34c-3p:mirSVR_lowEffct hsa-miR-34c-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-115 6.73E-112 9.92E-115 9.14E-114 314 1380 "SDE2,CLK4,SYS1,KLHL32,TMCC3,GALNT13,ADD2,ADRB2,BEND6,NLGN4X,C1QTNF3,ALCAM,ALK,CDC42BPA,DPP10,LCORL,PPFIA1,PARG,GPAM,CACHD1,API5,MADD,CASK,ARRB1,CDK13,PDE8B,DNAH17,DDX3Y,DYNLL1,ATM,NOL4,ATP6V0A1,BACH1,ADGRB2,BMPR1B,SYNJ2,FUBP1,THSD7A,VSTM2A,AIFM1,TMEM257,MYOM2,CDC42,KCNAB3,DCLK1,MAGI1,CACNA2D2,FOXN3,CHM,IGFBP7-AS1,ABCG2,FHL5,FAM149A,COL4A5,SLC25A27,SUMF2,AHCTF1,MYRIP,MFSD4A,CLOCK,ENTPD4,MICAL2,PDE4DIP,KIAA0040,ERC2,GREB1,FGFR1OP2,TOX,ARMCX2,YTHDC1,DNAJC6,MFAP3L,G3BP2,WDR20,KBTBD11,DLG2,GRIN3A,NR1D2,CASP8AP2,PDCD6IP,ECM2,DNAJB6,ABCC9,EDN1,SYT15,IRAK4,TMEM35A,EN2,SRRM1,KATNAL1,AMZ2,CEP78,FECH,KIAA1109,PRKAG2,FOXG1,CAP2,SYNCRIP,SGIP1,FLYWCH1,C2orf88,ZCCHC17,SMC2,UFM1,SARAF,TBR1,DKK3,HRASLS5,GABRA3,GABRG2,ARPP21,GDF9,TCERG1,GLRB,GLS,PCDH11X,ZNF638,CBX1,HTATSF1,RAB40B,WDFY3-AS2,PRUNE2,DIPK1C,STON1,PCLO,CNTRL,RAPGEF4,GRB10,DIDO1,LINC01551,GUCY1B1,UBE2QL1,C1orf94,HMGB1,HPSE2,HMGCR,AGBL5,HNF4G,HNRNPK,HTR2A,ICA1,ZNF181,IL6ST,KCNK3,KCNN2,CREG2,SYTL4,HECTD2,NCOA7,MAOB,MARK3,AQP11,MATN3,MBNL1,LRP1B,MEST,KITLG,POC1B,MMP16,ZNF92,MYO6,ZC3H12B,NDUFA5,NEUROD1,NFIA,OTOGL,NFYA,NINJ2,CNOT4,HCN1,NUCB2,OPHN1,KCNK10,PBX1,PCDH9,PCSK2,SSH1,CCSER2,PURG,PDZRN4,LRP12,ING3,MINDY2,PPP1R1A,TATDN3,CCDC144B,PPP2R5C,PPP3CA,PKN2,SLC26A11,RELN,VPS13C,SIDT1,SNRK,MDGA2,TMEM104,PLPPR1,UHRF1BP1,PTHLH,SPDL1,PTPRD,PTPRE,C1orf109,PLEKHB2,RASGRF1,ARID4A,RADX,BSDC1,ZYG11B,FIGN,RGS4,SLC25A36,ELP2,NEK11,ACER3,LGR4,SYNDIG1,HUNK,WLS,NCBP3,FAM182A,MIR124-2HG,ATXN2,ATXN7,LRRTM4,SCP2,SOX6,STUM,SCAF8,KIF21A,SEC31A,KANSL3,SEPHS1,SLC8A3,ELMO2,SLC22A4,SNRPN,PALLD,TMCC1,UNC80,DOP1A,KIF21B,CLUAP1,KDM4C,ZNF423,BEX1,DDN,LMO3,TAB2,ITPRID2,LARP4,CEP68,DIP2A,NSFL1C,FGD4,VPS13A,PLCB1,SYN2,CAMTA1,FBXW11,ANO4,VWA3A,SATB2,PCDHGB7,PCDHB4,PUM2,GPRIN3,TEK,FAM200B,DICER1,ZNF106,BHLHB9,KAT6B,RASD2,C9orf85,RGMB,ZNF346,SYNPO2,METTL3,TRPS1,DCBLD1,ANKRD20A2,TTPA,TMEFF2,FAM155A,AMOT,PITPNB,USP1,CCDC14,TBC1D15,ETNPPL,LGI4,PCDH20,ZNF24,FMN2,PLPP4,TMEM237,WNK1,EMSY,DNALI1,STOX2,PCDH15,KCNAB1,FIP1L1,FAM47E,C12orf4,HRASLS,ADAMTSL3,ZNF248,TTC7A,NETO1,AP3B2,SOCS4,SLC4A10" MicroRNA hsa-miR-582-3p:mirSVR_lowEffct hsa-miR-582-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-115 7.27E-112 1.07E-114 9.86E-114 325 1475 "ACHE,CSMD3,KIAA1211,BEND6,DPY19L2P4,SLC44A5,ZNF608,KCTD16,OSBPL8,FAM135A,CDC42BPA,DPP10,SUGT1P4-STRA6LP-CCDC180,APP,SFMBT2,CADPS,CDK13,ASPH,DACT3,CHID1,SLC4A4,STX16,SLC2A11,RNF182,PROM1,JAZF1,IL33,BTRC,CFAP410,THSD7A,TRIM41,CBR1,TMEM257,CDH8,ZMYM4,LGI1,TIGD7,NOG,CACNA2D2,CFL2,SRSF11,CHM,JAM2,NDST3,KIAA1549L,NRXN1,FBXO7,MAP4K4,CNN3,PCYT1B,COL4A5,LETMD1,SLC4A8,RCHY1,CREB5,GDA,RGS6,OSBPL3,ATRNL1,APPL1,PPP6R2,DCAF4,CYBB,MYADM,TOX,RASSF2,MATR3,AIF1L,ZBTB24,FBXL5,G3BP2,MTX3,SEC16A,DMD,OLIG1,DYNC1I1,DPYSL2,DSCAM,RCAN1,ABCC5,ABCC9,EDN3,SYT15,SEMA3D,TMTC1,YAF2,KMT5B,GOLGA7,ASB3,KCTD3,EIF4G2,SORBS3,PLEKHA1,ING4,ELAVL3,EPHA5,KCNMB2,KATNAL1,CLVS1,ZNF461,ATP8A1,RACK1,FKTN,MED12L,CAMSAP1,POLK,MEX3B,PCYOX1,SYNCRIP,AGAP3,FOXO3,FLT1,EFCAB2,ERGIC3,KHDRBS3,CELF1,NSG1,PNMA2,AP4B1,STAG2,MEGF11,GAB1,GABRB3,HBS1L,GALC,ERAP1,ZNF559,KIAA1841,CPLX1,DNER,NEU3,TUBGCP4,TUBA8,ADAM28,BRD8,TOX3,ZNF638,KDM2B,GNAS,LNX1,GOLGB1,GPD2,ATF7,GPR12,PCLO,SPACA9,NR3C1,GRM5,GRM7,CLASRP,LINC01551,PSIP1,ADAMTS6,GYG1,HAS2,ZHX1,USP51,HSF2,LRRC75A,SMAP1,DOCK7,BRINP3,DIPK1A,INPP5B,ITGAV,KCNC2,KCND1,GPR62,KCNJ16,KCNMA1,ARHGAP12,MAP2,MAT2A,XRRA1,N6AMT1,MYO6,MYO9A,NAP1L1,NAP1L3,NDUFA5,CCDC13,NEUROD1,NOVA1,DNHD1,SMIM11A,NTRK2,OMG,P2RY1,PAK3,PBX1,PCDH9,PRTG,PDE4D,PDGFRA,BEST3,NLGN3,PIK3C2A,ZFYVE21,MTRF1L,ING3,MINDY2,PPP2R2B,CRLS1,PKIA,MAPK4,MDGA2,PTCH1,UHRF1BP1,PTK2,PTPN13,PTPRE,PTPRG,TMEM231,PPP2R3C,FAT4,NWD1,RADX,RDX,ZMAT4,GTDC1,RGS10,RNF220,SLC25A36,RPRD1A,ROBO2,CCDC102B,TMEM100,RPL15,ZC3H14,PRR5L,LGR4,RPS20,ZNF331,AMER2,SALL1,MIR124-2HG,SFPQ,MRAS,KIF27,ITSN1,SH3GL2,NTNG1,PPP4R3A,RUFY2,CCDC88A,SLC9A5,SLC15A2,TMEM132D,SLCO1A2,SPHKAP,COA1,RIMS1,MBD5,TMCC1,ZCCHC24,ZSWIM8,SP4,CAND2,HECW1,ZNF423,BEX1,DBNDD2,CDK19,ITPRID2,STOX1,NKAIN2,NXT2,CEP68,KANK1,NECAB1,DNAJC9,COBL,ATP11A,KAZN,CAMTA1,TAF6,DNMBP,TBCEL,ZFP90,ZEB1,TRIM2,WDR7,AZIN2,DOCK9,PCDHB9,PUM2,HIF3A,RNF216P1,DICER1,SIRT1,ITGB3BP,HHIP,FBXL16,ACTR6,TMOD1,TP53BP2,RGMB,SYNPO2,STXBP4,TRPS1,RUSC1,CLHC1,UBE2H,MTCH1,ZNF781,CELF4,REEP1,SH3GLB2,WNK1,CADM2,EVI5,LINC02210,STMN4,HPS4,CIAPIN1,PDSS2,RGS7BP,KAT6A,FAM219B,ADAMTSL3,ZNF248,FRMD6,RNF146,SOCS4,JPH3" MicroRNA hsa-miR-4288:mirSVR_lowEffct hsa-miR-4288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.49E-115 8.34E-112 1.23E-114 1.13E-113 332 1537 "ABR,SYN3,SYS1,ACTN1,CSMD2,PLEKHG5,DSCAML1,SORCS1,KIAA1211,SNX30,MTA3,DISP3,ALAD,ABCD2,CARNS1,GOLGA7B,PPFIA1,SUGT1P4-STRA6LP-CCDC180,FAM131A,APP,LGR5,AQP4,CDC14B,ARNTL,ARRB1,NUMB,CHID1,ATP1A2,ATP2B1,SLC2A11,CADM3,RIPK1,DCAF5,FGF17,SYNJ2,ARHGEF7,FUBP1,LINC00906,CACNA1I,MMD2,CACNA1A,CACNA2D1,CALB2,CABP7,BRSK2,ISPD,SPAG9,MAP7,P2RX6,SCARB1,MYOM2,CDH8,CDH10,LRRFIP1,CLGN,CACNA2D2,CASC2,NDST3,EPS15L1,KIAA1549L,NRXN2,TPP1,DGCR9,TJP2,QKI,MAP4K4,NIPBL,FAM149A,WHRN,SUMF2,LETMD1,ABI3BP,SMARCAL1,TOGARAM2,MFSD4A,CPS1,PREPL,HAPLN1,GDA,ARHGEF10,NCAN,DZIP3,PHF14,GREB1,GPSM1,DOCK4,ARHGAP32,KATNAL2,SNPH,ARHGAP24,TOX,PHF19,EARS2,ZNF337,LIN54,MATR3,DGKB,DAPK1,IP6K1,DGCR5,BLOC1S6,SV2B,SPOCK3,SGSM2,HS3ST2,DMTF1,PDCD6IP,GNE,DTNA,DUSP9,ABCC9,GOLT1B,EDNRB,MBNL2,EGR3,EIF5,CERCAM,ELN,ENPP6,SPEG,TMEM74,EXTL1,F8,CLVS1,ZNF589,FGFR1,PRKAG2,MEX3B,SEMA4D,PSD2,EFCAB2,PDLIM5,KHDRBS3,DACH2,STAU2,ABLIM2,MEGF10,GABRA1,GABRB3,SALL3,IP6K3,MTHFD2,ATP8A2,CPLX1,ALDH1L1,WDFY3-AS2,LILRB4,GPD2,GPR12,GRIA2,GRIA4,PLCD4,ADAMTS13,ADAMTS8,MFSD2A,AP4S1,ADAMTS6,ATOH8,RASSF8,PADI2,MAN1B1,ATXN2L,ZNF491,CELF5,FAM95B1,C2orf72,LRRCC1,BRINP3,DIPK1A,INSM1,ITPKB,KCNH1,KLRC3,L1CAM,LAMP2,HECTD2,NCOA7,GPR155,MAN2A2,ZFYVE27,LYPLAL1,MDM4,MEIS1,MEIS2,MID1,PPM1L,XRRA1,DBNL,ADAM22,MT3,C10orf105,MXI1,LAYN,ZNF862,NAP1L1,NCAM1,NF1,ALDH1L2,CHAMP1,OPCML,P2RX7,SNTG1,PDGFRA,GPR173,NLGN3,TMIE,PIK3R1,ANKRD16,PPP2R5C,PPP3CB,PRKAB2,PRKACB,PRKCB,PKN2,MAPK9,RELN,QRICH1,UHRF1BP1,MTMR10,ELOVL2,ZIK1,PEX5,ZNF844,CEP97,SLC25A48,OXR1,ARID4A,ZDHHC14,RET,RGS3,RGS4,TTLL7,SEC61A2,SLC25A36,RIC8B,PBRM1,RNASEL,RNH1,LGI2,CCDC102B,BAALC,SPIN3,ATP8B4,CLIP1,S100B,DGLUCY,FOXRED2,SEMA6D,SCN2B,SCN8A,FNIP1,FOXRED1,FERMT1,MYO18A,NTNG1,R3HDM2,ST6GAL1,SLC8A1,SLC12A4,NAPB,SCMH1,SPHKAP,NAXD,CDK5RAP2,MBD5,KDM4B,SOX5,BDP1,KDM3A,CAND2,HECW1,KIF1B,MCF2L2,RBM26,ITPRID2,ZC4H2,NKAIN2,ZSCAN29,ADHFE1,FGD4,JMJD6,ADAMTS17,TAF6,WWC1,TBL1X,ANO4,TCF7L2,PHF24,USP32P1,CRB1,TIAM1,TMEM9,TLL2,BHLHB9,LRRC8A,RBFOX2,C9orf85,TRIO,TRPS1,PPIL6,SSBP2,RFTN2,RPL7L1,UCHL1,SLAIN1,MGAT5B,MTCH1,CLIP2,LAT2,SF1,ZIC1,CFAP52,ZBTB38,ZNF177,ZFAND5,CIAPIN1,PCDH15,NAV3,LINC00632,PCBP4,PLSCR4,PARP11,HRASLS,PAK5,FBXO36,FAM219B,JMJD1C,TRAM2-AS1,FRMD6,IFT88,NETO1,GAN" MicroRNA hsa-miR-769-5p:mirSVR_lowEffct hsa-miR-769-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-115 1.42E-111 2.09E-114 1.92E-113 320 1435 "ASIC1,ABHD6,NDRG3,ADAR,KLHL32,ADCY6,ADD2,AP2A2,HACE1,OSBPL1A,CC2D2A,SEMA6A,CEP126,CARNS1,ZFAT,PI16,SUGT1P4-STRA6LP-CCDC180,DGKZ,PHYHD1,APP,IGDCC4,MARK4,DACT3,RASL11B,ASTN1,NOL4,DPY19L3,BAIAP3,MMD2,CA12,HAP1,VXN,BRSK2,SLC16A4,ARHGEF1,CD38,ENTPD6,LRBA,CDO1,CCPG1,NUMBL,CASC2,PLAA,TPP1,FADS2,SLC4A8,ABI3BP,AHCTF1,TOGARAM2,CREB5,SEC24C,NCAN,PNPLA8,CTNND1,DCAF4,RUBCN,CX3CR1,KIAA0408,GAPVD1,ZFYVE16,TBC1D5,PHYHIP,DGKG,DAPK1,KIAA0753,CEP170,DDX46,SMG7,SV2B,TMCC2,CCDC3,KBTBD11,DLG2,DNM2,DPP6,ABI1,SH3GLB1,COPS4,ING4,VPS13B,SEZ6,GPHN,ANKRD13B,IGSF6,EFS,ZNF549,SPEG,MRPL37,EZH1,F5,ABCA8,FAM198B,ZNF461,CORO2B,TOMM40L,FGF11,SPSB4,PRKAG2,POLK,SUCO,SCARA3,SEC23B,PSD2,AKAP3,DPYSL4,ERGIC3,KHDRBS3,TBR1,AP4B1,TVP23A,NEURL4,GALC,IP6K3,GHDC,ATP8A2,WASF3,GPR162,GLI2,GLYR1,GLS,KCNMB4,GPD2,PRUNE2,CECR2,RFFL,SPACA9,GRIN1,PRDM5,KAT7,FAM107A,ARHGAP19,HMGB1,HMGCR,LINC00667,IFI16,DISP2,LIX1,METTL21A,KCNK3,CREG2,KIF5A,KIF5C,STMN1,SFXN5,ZFYVE27,AQP11,SYT9,ADAM11,CHIC1,MDM4,MGAT3,SCAMP5,PPM1L,MSI1,CTNNA3,MTTP,MYO7A,NEXMIF,PABPC1L2A,NAP1L1,FXYD6,NELL1,NUCB1,OPCML,PCSK2,PDE1A,PDE2A,PDE1B,PDGFRA,ZDHHC8,NLGN3,SEMA5B,CAMKV,TMIE,ANLN,FAM218A,CCSER2,MAPKAP1,SCHIP1,ING3,EPB41L4B,TNPO2,FSD1,POU6F1,TMEM235,PRKAB2,MAPK9,PROX1,MASP1,SIDT1,GON4L,ELOVL2,ZIK1,PTPRH,PEX2,ZSCAN2,NKAIN1,MARCH1,ATG16L1,RASGRF1,RASGRF2,ZDHHC14,GTDC1,RNF220,SLC25A36,ZNF532,EPHA10,FBXW7,ADAL,STK32B,EMID1,LRRK2,HSD11B1L,ZNF354C,FAM192A,AP1AR,MAPK12,ATXN2,FAM19A1,ASIC4,CASC3,SCAF8,SH3GL2,DOCK10,HKDC1,MAGI3,ST6GAL1,CTXN2,WDR37,EPN2,PKNOX2,LRRC55,SLC8A2,ARHGEF40,SLC11A1,SLC12A4,SMARCA4,SMARCC2,ANKRD36,MYT1L,CAND2,LHFPL4,IDI2-AS1,BEX1,ZBTB43,MCF2L2,RBM26,CLASP2,CLSTN2,ITPRID2,EPB41L3,ZC4H2,SS18,DIP2A,SEPT3,GSE1,FAM168A,FGD4,PRRC2C,VAMP1,ARHGEF9,VPS13A,ADAMTS17,DNAJC9,ARC,SYP,MTCL1,MLST8,UNC5D,ADGRL3,FBXW11,TBL1X,TBX15,EHBP1,CUX2,TCF12,CLASP1,SZT2,DOCK9,PSD3,PCDHB4,AHCYL2,AP4E1,GALNT17,TIAM1,TMPO,RASD2,NPL,TPM2,ZNF346,ELP5,TRPS1,TMPRSS5,TSN,UBTF,LINC00689,BEST1,LGI4,SF1,ZNF28,FMN2,ZBTB38,POLR3H,FSTL5,DPYSL5,PCBP1-AS1,EMSY,LINC02210,SLC17A6,AMN1,DOCK8,UBE3B,CASC15,CERS6,ZNF248,MSRB3,IFT88,RNF146,AP3B2,ST8SIA2" MicroRNA hsa-miR-151-3p:mirSVR_lowEffct hsa-miR-151-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.56E-115 1.44E-111 2.11E-114 1.94E-113 295 1225 "ABHD6,NBAT1,CSMD3,NDRG3,DSCAML1,ERMN,PLEKHH1,ADRB2,BEND6,TBC1D14,CC2D2A,AK2,LRRC7,GPRASP2,AMPD2,FGD2,ANXA7,ZNF583,ADGRB3,LINC00847,BMPR1B,DST,SYNJ1,SYNJ2,FUBP1,LINC00906,NIPA1,CALB1,KALRN,PTBP2,SPAG9,CLDN10,INA,SEPT7,CDC27,LRRFIP1,CDO1,CCPG1,CHN2,KMT2C,TPP1,CLTC,FADS2,ABCG2,QKI,MAP4K4,TMEM155,FHL5,SLC4A7,ABI3BP,RCHY1,MYRIP,ZNF521,MFSD4A,CDC42BPB,SEC24C,SUSD5,IPCEF1,NCAN,PLXNA4,FAM169A,SLITRK5,PPP1R16B,ERC2,GREB1,CTNND1,USP6NL,CX3CR1,CCDC144A,HDAC9,ARHGAP32,TOX,TBC1D5,GIT2,ZBTB24,ELMO1,FBXL5,FBXO25,ZC3H11A,RHOBTB1,SRGAP3,NTM,DMD,DNM2,CPEB2,DOCK2,ABI1,ABCC9,HIPK3,EFNA3,SH3GLB1,PHF20L1,TENM1,PLEKHA1,LRRC17,SEZ6,GMPR2,MRVI1,CORO2B,CEP78,FKTN,GTF2IRD2,FGF12,TMEM164,POLK,UBE2E3,HPCAL4,IP6K2,COQ5,UFM1,ATP6V1H,KHDRBS3,CGREF1,CSPG5,MEGF11,MEGF10,GAB1,GABRA2,CAB39,HBS1L,SIGLEC8,GART,DNER,MSTN,GFAP,GGTA1P,GLYR1,RAB30,TNRC6A,KIAA1958,PRUNE2,LILRA1,GRB10,GRM7,GRM8,FAM19A2,MAP4K5,IGSF21,SCRG1,AGBL5,IRF8,MSL1,LIX1,ZNF678,INPP5B,NME9,ITGA7,KCNA2,KCNC1,KCNC2,STXBP5,LAMA2,INSYN2,SYTL4,MAP2,MEF2C,MEIS2,CCDC80,BLOC1S2,MSRA,MTTP,NCAM1,NDUFA5,SLCO1C1,CNOT4,NRGN,SMIM11A,HCN1,NUMA1,OMG,OPCML,FAM225B,PAX6,PDE1C,PDE4D,PDGFRA,FAM98B,NALCN,PIK3C2A,ZNF655,GPSM2,PLP1,STRN3,ING3,SPATA6,NXPH1,POU3F2,PPP3CA,PPP3CC,CEP41,MASP1,SNRK,ANKHD1,EML5,PTPRH,TUG1,RADX,RET,FIGN,RFX3,RFX5,UBR7,RGS3,RGS12,EXD2,ARMH4,ZNF671,ATP8B4,PRR5L,ATAT1,ATXN7,HOGA1,ASIC4,SOX6,CASC3,GALNT10,ASAP3,CHD9,ANKRD6,FAM214B,YPEL4,SLC8A1,SLC12A4,NAPB,BTBD7,SORCS3,SMARCE1,SNRPN,UNC80,FAM219A,DOP1A,SON,TNIK,BDP1,UHRF1BP1L,BEX1,CDK19,SPART,ATP10B,NXT2,ZSCAN29,RGL1,SEPT3,STXBP1,SYT11,FGD4,VAMP1,ADAMTS17,COBL,SYT4,FBXW11,TPCN2,CLASP1,DOCK9,PHF24,RALYL,TNS2,AHCYL2,FAM200B,SIRT1,LEFTY2,KAT6B,PIK3R5,ELP5,TRPC1,TRPS1,RUSC1,TSC1,FAM155A,AMOT,UGT8,PITPNB,BCL2L13,CCDC14,VLDLR,XRCC4,LGI4,ZNF540,ATP6V0E2,ZBTB38,AMZ1,SYNC,WNK1,EMSY,PRDM2,ADAMTS9,MDH1B,NAV3,TMEM163,TRIM16L,MVB12B,PAK5,GAN,FAM198A,JPH3" MicroRNA hsa-miR-199a-3p:mirSVR_lowEffct hsa-miR-199a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-115 2.13E-111 3.11E-114 2.87E-113 311 1360 "ACADM,ASIC2,GALNT16,SLC12A5,SORCS1,PLEKHH1,PTCHD1,BEND6,INTS2,HECW2,TBC1D14,OSBPL8,TXNDC16,CC2D2A,ARHGAP20,FAM135A,ZFAT,LCORL,PKP4,APBB2,LRRC4C,API5,USP37,TMEFF1,ZFYVE28,ARNTL,NUMB,N4BP2L1,CFLAR,CDK5R1,IL33,CACNB4,CALB1,CAMK2G,VXN,PRC1,CBFA2T2,ARHGEF2,REPS2,CDC42,LGI1,LOC730101,CCPG1,NOG,NUMBL,JAM2,NRXN3,PLAA,PPT2,CLCN3,C4orf33,PCYT1B,SLC4A8,MAGED1,RCHY1,ACBD5,HS3ST5,CDC42BPB,RBM39,AKAP12,NCOR1,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,CCDC144A,HDAC9,TOX,TBC1D5,TMEM170A,GIT2,ARMCX2,HP1BP3,KLHL3,FBXO25,RHOBTB1,SEC16A,ABI1,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,ENO2,EPB41L1,EPHB1,ERBB4,PIPOX,F5,FAM198B,WAC,FABP7,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,RGPD5,FOXM1,FLT1,SORBS1,UFM1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,KHDRBS3,NSG1,MPP6,GABRA1,ILDR2,HBS1L,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GLS,GNAL,GNAS,LNX1,PRUNE2,TPPP,GRB10,GRIA1,GRM5,CIT,KAT7,ZBTB49,FAM222A,IRAK3,FRMD5,MAN1B1,IGFBP1,TJAP1,KCND2,KCNK1,KIF5A,KIF5C,IPO5,STMN1,ZFYVE27,MAPT,MBD1,LRP1B,MEF2C,PPM1L,AFDN,ZNF680,BLOC1S2,LYRM9,LAYN,P2RY13,NEUROD1,SLCO1C1,NFYA,SLC11A2,NTRK2,SETD4,IGSF11,ODF2,OPA1,GPR137C,PDE3B,SEMA5B,PIK3R1,CCSER2,ZFYVE21,PKM,PLP1,HMGCLL1,STRN3,FA2H,MED1,PPM1B,TATDN3,CCDC144B,PPP3CA,PPP3CB,PRKACB,RAB39A,MAPK4,HYDIN,VPS13C,WDR25,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,PTX3,ZNF615,TUG1,FAM66C,FAM184A,RAP1GDS1,KHDRBS2,RFX4,RGS3,RIC8B,TMLHE,EXD2,ROBO2,TCP11L1,ABCA11P,ZNF331,ATXN7,FAM19A1,TNFRSF19,TRIM46,TRA2B,ITSN1,PPP1R9A,SHC4,FBXO11,CCDC92,NLGN1,ANKRD6,PAAF1,PEX26,RAB3GAP1,SLC12A2,SLIT1,SORCS3,UNC80,KDM4B,TNIK,BDP1,RBM26,ATP10B,CLSTN2,ITPRID2,STOX1,SSTR1,LARP4,STAU1,RGL1,DIP2A,STAC2,ADHFE1,KLHL7,SYT4,FAM208A,ADGRL3,FBXW11,SIN3B,ZEB1,TPCN2,DOCK9,ARHGEF12,ATP13A2,DNAH7,ZFPM2,ITGB3BP,ZNF106,AKTIP,MTMR14,NACC2,TJP1,RIMBP2,PRMT8,DCBLD1,TMPRSS5,TTC3,TMEFF2,HEPACAM,AMOT,DNAJC12,USP1,BEST1,CFAP298,PCDH20,ZFP37,ZIC3,ZNF711,WNK1,PRDM2,SLC38A1,EVI5,STOX2,CIAPIN1,PCDH15,NAV3,FAM47E,PDSS2,DNAH10,PAK5,PHTF2,JMJD1C,TIGD6,MSRB3,SOCS4,CPNE4" MicroRNA hsa-miR-199b-3p:mirSVR_lowEffct hsa-miR-199b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-115 2.13E-111 3.11E-114 2.87E-113 311 1360 "ACADM,ASIC2,GALNT16,SLC12A5,SORCS1,PLEKHH1,PTCHD1,BEND6,INTS2,HECW2,TBC1D14,OSBPL8,TXNDC16,CC2D2A,ARHGAP20,FAM135A,ZFAT,LCORL,PKP4,APBB2,LRRC4C,API5,USP37,TMEFF1,ZFYVE28,ARNTL,NUMB,N4BP2L1,CFLAR,CDK5R1,IL33,CACNB4,CALB1,CAMK2G,VXN,PRC1,CBFA2T2,ARHGEF2,REPS2,CDC42,LGI1,LOC730101,CCPG1,NOG,NUMBL,JAM2,NRXN3,PLAA,PPT2,CLCN3,C4orf33,PCYT1B,SLC4A8,MAGED1,RCHY1,ACBD5,HS3ST5,CDC42BPB,RBM39,AKAP12,NCOR1,IPCEF1,PDE4DIP,PHACTR3,CNTNAP2,CST3,PLCXD3,CCDC144A,HDAC9,TOX,TBC1D5,TMEM170A,GIT2,ARMCX2,HP1BP3,KLHL3,FBXO25,RHOBTB1,SEC16A,ABI1,DRP2,GOLT1B,AASDH,WDPCP,SEMA3D,KLHL5,KMT5B,ASB3,EIF5,TENM1,PLEKHA1,ENO2,EPB41L1,EPHB1,ERBB4,PIPOX,F5,FAM198B,WAC,FABP7,ACSL4,FCGR1A,CEP78,OLFM1,FGF13,BAIAP2,FHL1,POLK,RGPD5,FOXM1,FLT1,SORBS1,UFM1,FAM49B,ATP6V1H,ATP2C1,ERGIC3,KHDRBS3,NSG1,MPP6,GABRA1,ILDR2,HBS1L,IQGAP2,ERAP1,MTHFD2,C15orf41,KIAA1841,NEU3,ALDH1L1,GCNT2,MSTN,GDF9,PCDH17,GLS,GNAL,GNAS,LNX1,PRUNE2,TPPP,GRB10,GRIA1,GRM5,CIT,KAT7,ZBTB49,FAM222A,IRAK3,FRMD5,MAN1B1,IGFBP1,TJAP1,KCND2,KCNK1,KIF5A,KIF5C,IPO5,STMN1,ZFYVE27,MAPT,MBD1,LRP1B,MEF2C,PPM1L,AFDN,ZNF680,BLOC1S2,LYRM9,LAYN,P2RY13,NEUROD1,SLCO1C1,NFYA,SLC11A2,NTRK2,SETD4,IGSF11,ODF2,OPA1,GPR137C,PDE3B,SEMA5B,PIK3R1,CCSER2,ZFYVE21,PKM,PLP1,HMGCLL1,STRN3,FA2H,MED1,PPM1B,TATDN3,CCDC144B,PPP3CA,PPP3CB,PRKACB,RAB39A,MAPK4,HYDIN,VPS13C,WDR25,ANKHD1,MTMR10,PTN,ZSCAN32,PTPRG,PTPRO,PTX3,ZNF615,TUG1,FAM66C,FAM184A,RAP1GDS1,KHDRBS2,RFX4,RGS3,RIC8B,TMLHE,EXD2,ROBO2,TCP11L1,ABCA11P,ZNF331,ATXN7,FAM19A1,TNFRSF19,TRIM46,TRA2B,ITSN1,PPP1R9A,SHC4,FBXO11,CCDC92,NLGN1,ANKRD6,PAAF1,PEX26,RAB3GAP1,SLC12A2,SLIT1,SORCS3,UNC80,KDM4B,TNIK,BDP1,RBM26,ATP10B,CLSTN2,ITPRID2,STOX1,SSTR1,LARP4,STAU1,RGL1,DIP2A,STAC2,ADHFE1,KLHL7,SYT4,FAM208A,ADGRL3,FBXW11,SIN3B,ZEB1,TPCN2,DOCK9,ARHGEF12,ATP13A2,DNAH7,ZFPM2,ITGB3BP,ZNF106,AKTIP,MTMR14,NACC2,TJP1,RIMBP2,PRMT8,DCBLD1,TMPRSS5,TTC3,TMEFF2,HEPACAM,AMOT,DNAJC12,USP1,BEST1,CFAP298,PCDH20,ZFP37,ZIC3,ZNF711,WNK1,PRDM2,SLC38A1,EVI5,STOX2,CIAPIN1,PCDH15,NAV3,FAM47E,PDSS2,DNAH10,PAK5,PHTF2,JMJD1C,TIGD6,MSRB3,SOCS4,CPNE4" MicroRNA hsa-miR-338-5p:PITA hsa-miR-338-5p:PITA_TOP PITA 4.22E-115 2.37E-111 3.46E-114 3.18E-113 235 773 "CLK4,FMNL2,PLEKHH1,PTCHD1,AP1B1,GPR158,HACE1,OSBPL8,LRRC7,SEMA6A,SPOP,ARHGAP20,FAM135A,CDC42BPA,DPP10,MAP4K3,APBB2,API5,CDC14B,TMEFF1,ARHGAP5,CAPRIN2,ZBTB10,DDX3Y,SLC4A4,ATP2A2,ATP2B1,CDK5R1,SYNJ1,WASF1,CALM1,LDB2,FMNL3,C1orf52,LRBA,ZMYM4,LARGE1,MAGI1,B4GALT6,SLIT2,KMT2C,RAB28,NRXN3,CLTC,NIPBL,ARHGEF6,CNR1,ARMC8,COL4A5,SLC4A7,MICAL2,ATRNL1,PUM1,KIAA0408,BOC,HDAC4,ZFYVE16,DGKG,DNAJC6,JAKMIP2,MYEF2,MTX3,WDR20,DMD,CDON,CPEB2,CASP8AP2,DYRK1A,GOLT1B,TMTC1,MBNL2,EGR3,TENM1,PAN3,EN2,KCNMB2,DENND4A,EYA1,F3,ACSL4,TAOK3,SCML2,EFEMP1,KIAA1109,FGF13,AMOTL2,CAP2,SGIP1,AFF2,NBEA,STAU2,STAG2,DNER,FAXC,GCNT2,MSTN,PCDH17,GHR,PPARGC1A,GLRB,PCDH11X,GNAS,FERMT2,GRB10,GRIA2,GRIA4,GRM7,CIT,FAM222A,WIF1,MIER3,NEGR1,RBPJ,LRRCC1,LRRTM3,JAK1,KCNJ3,MARK1,MBNL1,MEIS1,AFDN,MN1,MYCN,NEXMIF,NF1,NKX2-2,NNAT,NPTX1,HCN1,PCDH9,PDE4B,ENPP2,GNG2,PIK3C2A,PIK3R1,KCTD15,HMGCLL1,TRHDE,LRP12,SCHIP1,EPB41L4B,NXPH1,POU3F2,PPP2R5C,PKN2,GDPD1,RELN,SNRK,PTCH1,PTPRD,FAM120C,TMEM255A,OXR1,RGS4,RGS7,RIC8B,CLIP1,SAFB,ATXN1,ELMOD1,SOX6,TRA2B,KIF21A,SH3GL2,PPM1E,CPEB3,MAGI3,FBXO11,FNDC3A,R3HDM2,SLC1A2,WDR47,SLC6A1,SEPHS1,CPEB4,RCOR3,MBD5,PALLD,KDM4B,DOP1A,MYT1L,ZCCHC24,SOX11,SP2,BEX1,SPART,CLASP2,LRRC4,SS18,VPS13A,ADAMTS17,C3orf70,PLCB1,SYPL1,SYT1,TAC1,ATP11A,ANKRD12,CAMTA1,TAF6,CAMSAP2,FAM208A,ACSL6,TCF4,SATB2,DOCK9,PSD3,PUM2,TEK,DICER1,SIRT1,DAAM2,CSMD1,RBFOX2,RUNDC3B,TRPC1,TRPS1,TSC1,SGK3,UBE3A,WIPF1,PCDH20,ZIC2,ZNF711,TRIM9,LYPD6,ZFAND5,SMARCAD1,ADAMTS9,SLC17A6,GOPC,FAM13C,JMJD1C,SLC4A10,SENP7" MicroRNA hsa-miR-1826:mirSVR_lowEffct hsa-miR-1826:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.63E-115 2.60E-111 3.79E-114 3.49E-113 315 1395 "SERPINA3,KCNH8,ARID1A,CSMD3,ADCY6,ADD1,ADD2,SLC12A5,ERMN,SLC24A4,SLC44A5,AP2A2,HECW2,KLHL13,WDR35,OSBPL8,CC2D2A,HFM1,SEMA6A,MAP4K3,MAGEE2,NT5C3B,USP37,SHTN1,LGR5,AQP4,CDC14B,PPP4R4,ARSE,ASPH,ATP2B3,ALDH7A1,ADAM23,BCHE,RGS11,CFLAR,SYNJ1,LINC00906,BAIAP3,CDK5R2,CA8,CACNB4,CALM1,VSTM2A,MAP7,DCLK1,DLGAP2,RCBTB2,CHN2,JAM2,IGFBP7-AS1,SRP14-AS1,HECTD1,SLC4A8,ABI3BP,RCHY1,ACBD5,ZNF521,SLC35F1,CPS1,AKAP12,HAPLN1,GDA,TENM4,ATRNL1,KIAA0040,CTH,CCDC144A,HDAC9,ARHGAP32,RIPOR2,ARHGAP24,TOX,ZNF337,LIN54,DGKB,GIT2,JAKMIP2,CNIH3,MFAP3L,KIAA0753,CEP170,BLOC1S6,ALKBH8,SRGAP3,DLG2,DMD,SLC12A6,CASP8AP2,DPYSL2,ABCC9,WDPCP,SUGP2,KMT5B,RASA4,ASB3,EIF4G2,PLEKHA1,ING4,EPHA5,GPHN,MRPL37,MRVI1,F8,FAM198B,WAC,SCML2,TESK2,GORAB,SEC24B,MEX3B,SEC23B,CAP2,PCYOX1,ANKFY1,EFCAB2,SORBS1,CELF1,ST6GALNAC3,NSG1,DLL3,STAU2,PNMA2,NRG3,GABRG1,CAB39,ARPP21,KIRREL3,GJB1,GLI2,GLS,PCDH11X,LUZP2,FERMT2,LNX1,LILRB4,GPM6B,FUT10,GPR12,RAPGEF4,GRIK1,GRIK2,ZNF496,ADAMTS6,WIF1,IRAK3,MAEL,ZHX1,ARHGAP36,HMGB1,IL6ST,ITGA7,KCNA6,KCNN2,STXBP5,KTN1,HECTD2,PIK3AP1,MBP,MID1,AFF1,AFDN,MOBP,SESN3,ADAM22,MXI1,MYO6,NAP1L1,NAP1L2,NASP,NCAM1,ZC3H12B,IDNK,NELL1,NPR2,NUMA1,OPA1,OPHN1,CNTN3,PAX6,PCSK2,PDE3B,PDE4A,OLA1,GDAP1L1,XRN1,PURG,PRIMPOL,PSAT1,PRRX1,NXPH1,DIRAS2,RELN,WBP1L,SIDT1,DEF8,QRICH1,PIGG,CNTLN,BDNF-AS,FAM120C,IQSEC3,SUSD4,ARID4A,RBBP6,BSDC1,SLC6A15,ZYG11B,GTDC1,RGS4,MRPS18A,RNF220,CCDC82,ROBO2,CCDC25,RORB,ELP2,MCMBP,ACER3,CNTNAP3,MEG3,KCNIP3,FAM182A,TRAPPC13,TMEM156,MAPK12,CSRNP3,FAM19A1,SCN8A,LINC00461,FNIP1,FOXRED1,SCG5,ZFP30,KIF21A,ITSN1,FNDC3A,ST6GAL1,PAAF1,SLA,RUFY2,SLC9A5,KBTBD4,SLC12A2,ELMO2,SLC20A2,SLCO1A2,RIMS1,MBD5,LMBRD1,SNRPN,FAM219A,SOX3,SOX11,HECW1,KDM4C,PEG10,IQSEC2,DDN,C11orf87,TAB2,AJAP1,ROBO3,PDLIM2,ADGRL3,TMEM136,MGRN1,VWA3A,ATMIN,TCF4,WDR7,AZIN2,DOCK9,RALYL,DICER1,ZFPM2,ITGB3BP,ZFP91,C5orf64,PIK3R5,TP53BP1,C9orf85,TPM4,SMUG1,STXBP4,PPIL6,TSN,ANO5,TTTY15,TTC3,FLRT2,VLDLR,ZNF23,ZNF24,GPR158-AS1,TMEM237,SMARCAD1,INTS3,EVI5,RNF103,TUBA1A,VPS35L,KCNAB1,CAB39L,WIPF2,C12orf4,AMN1,MARCH8,UBE3B,CERS6,TIGD6,FXR1,DPF3,SOCS4,FAM198A" MicroRNA hsa-miR-506-3p:TargetScan hsa-miR-506-3p TargetScan 4.97E-115 2.79E-111 4.06E-114 3.74E-113 261 961 "ABR,ACADM,ASIC1,GALNT13,PLEKHH1,ESYT2,NLGN4X,KCTD16,OSBPL6,LRRC7,ALCAM,ABCD2,AMPD3,LRFN1,CDC42BPA,ANK1,PHF12,ANXA7,APBB2,CPNE5,PDXK,IGDCC4,CASK,ARHGDIA,CADPS,CDK13,ASPA,NOL4,DPY19L3,ADAM23,RGS9,BMPR1B,ARHGEF7,MTMR3,JAZF1,BSN,MYRF,MMD2,CACNA2D1,CACNB2,CACNB4,PTBP2,MAP7,CDC27,DLGAP2,CACNA2D2,CFL2,B4GALT6,JAM2,LHX2,QKI,CNGA3,CNN3,CNTN1,AKAP6,MYRIP,CPS1,CLOCK,NCOR2,LRIG1,OSBPL3,IPCEF1,PITPNM3,ERC2,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,LONRF1,KCTD8,IST1,AIF1L,GIT2,MAGI2,BLOC1S6,GUCD1,MTX3,FAM107B,DMD,NR1D2,CDON,DRP2,DTNA,DYRK1A,GOLT1B,E2F6,EBF1,FAM135B,EDNRB,PHC2,HIPK3,FEM1B,FSD1L,CELSR3,DCTN4,EN2,RAB9B,ETV1,RTN3,EXTL2,EYA1,MED12L,PRKAG2,PCYOX1,ANKFY1,C2orf88,NPTN,MPP6,GABRB1,AHCYL1,NEK6,NCKAP1,DNER,ARFIP1,GLRB,KIAA1958,GPM6B,FUT10,GPR22,GPR37,RAPGEF1,GRIA2,GRID1,RFFL,NR3C1,FAM19A2,RNF165,RASSF8,BACH2,HLF,ELOVL5,NEGR1,AGFG1,PLD5,OLFM3,KCNH1,KCNJ3,KCNJ5,KCNK2,KCNK3,KIF2A,KIF5A,PAXBP1,MARK1,MATN2,CHIC1,MID1,PPM1L,MITF,AFF1,MMP16,MN1,JAKMIP3,MSRA,MDGA1,MYO5A,NEFM,NEUROD1,NFIA,NFIX,CLDN11,P2RX7,KCNK10,CNTN3,PCDH8,CDK18,PDE2A,PDE3B,PDE4A,PDE4D,GPR85,PIK3C2A,PRRX1,FSD1,PPARA,PPP2R5E,CEP41,MAPK4,MAPK7,MAPK10,PROX1,QRICH1,PTPRD,EML5,QDPR,PID1,RAD17,RALGDS,ENOX1,DUSP15,MORC4,RFX3,RFX4,SEC61A2,ALG9,RAVER2,CYB561D1,RXRA,RYR1,RYR3,AMER2,SCN4B,SCN7A,CASC3,COPZ1,PPP1R9A,DZIP1,EPN2,RUFY2,CCDC88A,ATF7IP,LIMCH1,PALLD,FAM219A,PDZD2,KIF21B,GLT8D1,RAP1GAP2,NFASC,C11orf87,CAMTA2,EPB41L3,NKAIN2,NXT2,CEP68,PHLDB1,KANK1,RHBDL3,C3orf70,ATP11A,ATMIN,CRTC1,GPRIN3,DICER1,GZF1,NACC2,CBX5,RIMBP2,HEPACAM,CADM1,FRRS1L,OSBP2,KLC2,RICTOR,LYPD6,REEP1,EML6,DPYSL5,PMEPA1,CADM2,NT5M,CSDE1,LMAN2L,NAV3,NAV2,MARCH8,PHTF2,FAM219B,CBLN2" MicroRNA hsa-miR-124-3p.2:TargetScan hsa-miR-124-3p.2 TargetScan 4.97E-115 2.79E-111 4.06E-114 3.74E-113 261 961 "ABR,ACADM,ASIC1,GALNT13,PLEKHH1,ESYT2,NLGN4X,KCTD16,OSBPL6,LRRC7,ALCAM,ABCD2,AMPD3,LRFN1,CDC42BPA,ANK1,PHF12,ANXA7,APBB2,CPNE5,PDXK,IGDCC4,CASK,ARHGDIA,CADPS,CDK13,ASPA,NOL4,DPY19L3,ADAM23,RGS9,BMPR1B,ARHGEF7,MTMR3,JAZF1,BSN,MYRF,MMD2,CACNA2D1,CACNB2,CACNB4,PTBP2,MAP7,CDC27,DLGAP2,CACNA2D2,CFL2,B4GALT6,JAM2,LHX2,QKI,CNGA3,CNN3,CNTN1,AKAP6,MYRIP,CPS1,CLOCK,NCOR2,LRIG1,OSBPL3,IPCEF1,PITPNM3,ERC2,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,LONRF1,KCTD8,IST1,AIF1L,GIT2,MAGI2,BLOC1S6,GUCD1,MTX3,FAM107B,DMD,NR1D2,CDON,DRP2,DTNA,DYRK1A,GOLT1B,E2F6,EBF1,FAM135B,EDNRB,PHC2,HIPK3,FEM1B,FSD1L,CELSR3,DCTN4,EN2,RAB9B,ETV1,RTN3,EXTL2,EYA1,MED12L,PRKAG2,PCYOX1,ANKFY1,C2orf88,NPTN,MPP6,GABRB1,AHCYL1,NEK6,NCKAP1,DNER,ARFIP1,GLRB,KIAA1958,GPM6B,FUT10,GPR22,GPR37,RAPGEF1,GRIA2,GRID1,RFFL,NR3C1,FAM19A2,RNF165,RASSF8,BACH2,HLF,ELOVL5,NEGR1,AGFG1,PLD5,OLFM3,KCNH1,KCNJ3,KCNJ5,KCNK2,KCNK3,KIF2A,KIF5A,PAXBP1,MARK1,MATN2,CHIC1,MID1,PPM1L,MITF,AFF1,MMP16,MN1,JAKMIP3,MSRA,MDGA1,MYO5A,NEFM,NEUROD1,NFIA,NFIX,CLDN11,P2RX7,KCNK10,CNTN3,PCDH8,CDK18,PDE2A,PDE3B,PDE4A,PDE4D,GPR85,PIK3C2A,PRRX1,FSD1,PPARA,PPP2R5E,CEP41,MAPK4,MAPK7,MAPK10,PROX1,QRICH1,PTPRD,EML5,QDPR,PID1,RAD17,RALGDS,ENOX1,DUSP15,MORC4,RFX3,RFX4,SEC61A2,ALG9,RAVER2,CYB561D1,RXRA,RYR1,RYR3,AMER2,SCN4B,SCN7A,CASC3,COPZ1,PPP1R9A,DZIP1,EPN2,RUFY2,CCDC88A,ATF7IP,LIMCH1,PALLD,FAM219A,PDZD2,KIF21B,GLT8D1,RAP1GAP2,NFASC,C11orf87,CAMTA2,EPB41L3,NKAIN2,NXT2,CEP68,PHLDB1,KANK1,RHBDL3,C3orf70,ATP11A,ATMIN,CRTC1,GPRIN3,DICER1,GZF1,NACC2,CBX5,RIMBP2,HEPACAM,CADM1,FRRS1L,OSBP2,KLC2,RICTOR,LYPD6,REEP1,EML6,DPYSL5,PMEPA1,CADM2,NT5M,CSDE1,LMAN2L,NAV3,NAV2,MARCH8,PHTF2,FAM219B,CBLN2" MicroRNA hsa-miR-635:mirSVR_lowEffct hsa-miR-635:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.42E-115 3.05E-111 4.42E-114 4.07E-113 330 1526 "ABR,ASIC2,ACTN2,FAM43B,GPRIN1,GALNT16,ADCY6,KIDINS220,BEND6,OLMALINC,KCTD16,NME5,ALAD,USP35,ABCD2,ZNF687,PDZD4,SEMA7A,FGD2,FAM131A,PPFIA3,SHROOM2,AQP4,AQP6,PRX,SPTBN4,RNF182,ATP6V0A1,ADGRB2,SNAI3-AS1,RGS11,BCL2L2,CFLAR,KSR1,ARHGEF7,SCAPER,RAB29,IL33,CALB2,CABP7,CALM1,KALRN,NGB,CAMK2G,HIP1R,CLDN10,USP2,TMEM257,REPS2,MAGI1,RCBTB2,FOXN3,CHGA,SYNPR,NRXN3,TPP1,NMT2,NGEF,MAP4K4,PCYT1B,SLC25A27,LETMD1,MYRIP,ZNF385A,SEC31B,C2CD2,CREM,RNF14,HINFP,CS,SNCAIP,RGS6,ATRNL1,NCAN,SOCS5,CST3,DCAF4,FAM131B,CX3CR1,ECE2,CCDC144A,ARHGAP32,TOX,ZFYVE16,TBC1D5,IP6K1,ELMSAN1,CNIH3,KIAA0753,COPS7A,FBXO25,SV2B,DLG4,NYAP1,SLC29A4,CDON,DPH1,E2F6,TMTC1,FAM13A,ELN,EMX2,VPS13B,RABEPK,ERBB2,SPEG,FAM198B,WAC,FABP7,ZIC4,CORO2B,FCGR3A,STRADA,TESK2,FGF1,FGF12,HPCAL4,IP6K2,EVL,SEMA4D,FLT1,NOP56,FLYWCH1,COQ5,EFCAB2,SORBS1,ZBED3,PDLIM5,DACH2,FYB1,DKK3,HRASLS5,BRPF3,IP6K3,GAP43,DISC1,SEPT9,GART,WASF3,CYP46A1,USP19,GGT7,BRD8,RNPS1,GLI2,GLS,TNRC6A,ZNF638,GNAL,GNG4,WDFY3-AS2,GOLGB1,ADGRA3,PLCD4,GRIK2,GRM1,GRM7,ZBTB45,LINC01551,ATOH8,HAS2,PADI2,ARHGAP19,HNF4G,NEGR1,AGFG1,DHX35,SHISA6,C2orf72,RBPJ,SLC35G1,KCNC1,KCNH1,KCNJ5,KCNJ10,KCNJ11,KCNK1,GATD1,KIF5A,KIF5C,SYTL4,ZFYVE27,ADAM11,TM6SF1,MEIS1,MEIS2,MID1,MITF,XRRA1,WDR49,MSR1,HS6ST3,MYO7A,RTL5,NCF2,SLCO1C1,SNTG1,PAK3,PIRT,PENK,PFKFB4,NALCN,PIK3R1,ZNF655,FTO,PLXNB3,MAPK4,EPDR1,WBP1L,SYTL2,BDNF-AS,TMEM260,PTPRH,ZNF615,RAD52,FAM66C,RALGDS,NWD1,KHDRBS2,ZDHHC4,RGS3,RGS12,PRIMA1,RIC8B,ROBO2,CCDC25,MRAP2,SNX22,KIAA0895L,SGSM1,ADAL,CNTNAP3,WLS,ZNF331,SEMA6D,SCN2B,SCN8A,SCP2,FNIP1,TNFRSF19,SH3GL3,MYO18A,AMBRA1,FBXO11,ST6GAL1,ST3GAL3,CTXN2,ANKRD6,ABLIM3,SLC1A3,KANSL3,SLC12A4,NAPB,ATF7IP,SORCS3,CDK5RAP2,SNRPN,PALLD,TMCC1,UNC80,RBM34,USP33,FAM219A,DOP1A,SON,TSNAXIP1,SP2,KDM4C,PEG10,ZC3H13,ZBTB43,RAP1GAP2,DDN,C11orf87,TAB2,PBLD,ITPRID2,RGL1,SULF2,GSE1,SYNE2,VAMP1,NUDT10,SYP,SYT1,TACR1,KAZN,FAM208A,TMEM136,VWA3A,SYNE1,PHF24,RNF175,SIK3,TF,FAM200B,LEFTY2,AP4E1,ZNF106,TK2,DDHD1,TLL2,ZFP91,RASD2,C9orf85,TRIO,TRO,STXBP4,TRPC3,FNDC5,TSC1,SGK3,RPL7L1,VAV2,BEST1,PLPP4,NDRG4,SLC26A10,FTSJ1,SYNC,DHX33,GDPD5,HPS4,NAV3,C12orf4,RTN4,UBE3B,PIANP,IFT88,SOCS4" MicroRNA hsa-miR-875-5p:mirSVR_lowEffct hsa-miR-875-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-115 3.07E-111 4.45E-114 4.10E-113 298 1253 "ACTN1,CSMD2,FMNL2,KLHL32,ADCY6,PWWP2A,SLC44A5,MTUS1,CASKIN1,KCTD16,HACE1,OSBPL6,OSBPL8,LRRC7,BCAR3,OGT,CCDC146,CNIH2,PKP4,APC,ALS2,ARHGAP5,NCOA1,DDX3Y,NOL4,SEC11C,BCHE,BMP7,ARHGEF7,NIPA1,OSGIN2,BSN,CFAP410,CACNA1E,CACNB4,KALRN,CAMK2D,ZNF501,USP6,P2RX6,TMEM257,LRRFIP1,MAGI1,JAM2,NDST3,CLCN3,MYL6B,NMT2,DNAJB5,QKI,CNR1,PCYT1B,ARMC8,ANKRD35,COL9A1,SLC4A7,MYRIP,ZNF521,ZFP28,HS3ST5,CLOCK,PREPL,CREB5,HAPLN1,ANKRD44,VCAN,NCAN,PDE4DIP,SLITRK5,CTH,CTNND1,ST18,EDRF1,GPRASP1,HDAC4,KIAA0586,DGKG,TMEM170A,BRINP1,AIF1L,DNAL1,TIAM2,MFAP3L,ZC3H11A,SV2B,SRGAP3,RABGAP1L,CCDC3,DLG2,DMD,NR1D2,CPEB2,DOCK2,DPYSL2,PDCD6IP,DYRK1A,EDN3,APH1A,GOLGA7,PCOLCE2,COQ7,RABEPK,CEP85L,ETV1,CLVS1,NSRP1,DLC1,ZSCAN30,TESK2,FER,FGF12,MEX3B,FOXG1,SEC23B,PCYOX1,SGIP1,NPTN,ZNF605,DACH2,ST6GALNAC3,STAU2,TMEM151A,NRG3,GABRG2,BRPF3,ERAP1,SIGLEC8,DNER,GATM,GFRA1,MALT1,TCERG1,LUZP2,LOXL3,GNG3,EML4,CECR2,GRB10,GRIA4,GRID1,GRM7,LINC01089,SOX21,MAEL,FRMD5,PACSIN2,ATXN2L,MIER3,ZDHHC15,HTR2A,IDH3A,C2orf72,DOCK7,IL6ST,INPP5B,SLC35G1,KCNA1,KCNJ11,KCNK2,KLRC2,INSYN2,ASPRV1,SMAD9,CHIC1,MEST,AFDN,MMP16,MOG,MSR1,RSPO2,NDUFA5,NELL1,NEK1,NFIA,OCRL,GLIPR1L2,PBX1,DPY19L2P2,PCDH9,PCSK1,PCSK5,PDE3A,PDGFRA,CDK14,SERPINE2,NALCN,NOMO2,FAM218A,PLCB2,MTRF1L,MAPKAP1,RC3H2,LRP12,ING3,EPB41L4B,PACSIN1,MED1,MINDY2,PPP1R1A,CRLS1,PPP2R5E,RASGEF1B,CEP41,PRKCZ,DIRAS2,DCHS2,ZIK1,ZNF493,ARID4A,DBX2,SLC6A15,RET,GTDC1,PBRM1,RNASEL,ZFHX4,DCUN1D2,TMLHE,CARF,ZNF568,TRAPPC13,SEMA6D,PEAR1,SH3BGR,SH3GL2,SH3GL3,KIF16B,HKDC1,PAAF1,SLC1A7,DHX30,SLC8A3,ATF7IP,TET1,ZNF667,RIMS1,SNRPN,UNC80,SCN3B,SON,BDP1,TEX2,PEG10,KIF1B,DDN,SMOC1,ZSCAN29,KANK1,ZC3H4,SYT4,FAM208A,KIAA1107,ANO4,TCF4,TCF12,OBSL1,ARHGEF12,DDHD1,ZFP91,RIMBP2,SEZ6L,NPL,PDSS1,STXBP4,TRPC1,TTC3,PRR18,CLHC1,FAM155A,OSBP2,FLRT2,ZNF709,PLPPR2,RICTOR,CFAP52,TRIM9,ZNF142,ZBTB16,ANKS1B,SPIRE1,PLPPR5,WNK1,MFF,CADM2,STOX2,LMAN2L,HPS4,URM1,NAV2,FAM47E,PDSS2,EPM2A,FAM13C,MRPL47,JMJD1C,RNF170,NETO2,GAN" MicroRNA hsa-miR-4324:mirSVR_lowEffct hsa-miR-4324:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.11E-115 3.43E-111 4.96E-114 4.57E-113 355 1752 "ABCF1,ASPHD1,GPRIN1,FMNL2,PSMG3-AS1,ADD1,ERMN,USP31,PTCHD1,OLMALINC,WDR35,CC2D2A,AK2,LRRC7,MARCH4,ZNF687,CDC42BPA,PPFIA1,DGKZ,UPRT,CACHD1,AQP6,CDC14B,CDK13,NUMB,ZNF583,SLC2A11,ADAM15,BACH1,LINC00847,BCL2L2,CACNA1G,OSGIN2,CA4,CACNA1B,CACNG1,DIRAS1,PTBP2,BRSK2,CBS,USP2,P2RX6,CD38,CDC25B,ZBED1,L3MBTL4,LARGE1,PLEKHB1,NDST3,RAB28,CLCN4,MAP4K4,NIPBL,CNN3,SUMF2,SLC4A8,TOGARAM2,ZNF385A,SEC31B,CDC42BPB,ANKRD44,MICAL2,CSNK1G3,SUSD5,PDE4DIP,PPP1R16B,APPL1,GREB1,CTNND1,ZSCAN23,CCDC144A,NOS1AP,CYBB,ARHGAP32,RIPOR2,EARS2,ZNF337,IST1,SPOCK2,C8orf34,HEPH,COPS7A,GSDME,SMG7,SV2A,FAM107B,CHRDL1,EXOG,GRIN3A,DOCK2,DPH1,DPP6,ARRDC4,DTNA,DNM1L,ABCC9,KRBA2,HIPK3,KLHL5,PHF20L1,APH1A,MBNL2,ABI2,EGR3,TMEM132E,GOLGA7,RGS17,STARD3NL,EPB41,EPB41L1,EPHA5,STX2,SPEG,RASL12,RRAGB,STRADA,GTF2IRD2,TMEM164,CAP2,SYNCRIP,ATP13A4,NBEA,SORBS1,SMC2,STAMBP,ERGIC3,STAU2,ZNF512,FYN,HRASLS5,GABRB3,ARPP21,TMEM8B,ACSS1,WASF3,KIAA1841,ALDH1L1,USP19,CRCP,TNRC6A,PRUNE2,GPM6A,GPR12,NUDT21,CECR2,DIDO1,ADAMTS8,GRM3,RNF165,PTPN5,BVES,RABL2A,BACH2,HMGCL,HMGCR,AGBL5,OPALIN,MSL1,FAM95B1,RBPJ,DOCK7,IL6R,C2CD4C,KCNA1,KCNJ10,KCNK3,KCNMA1,KHK,CREG2,KLRC2,STXBP5,TTYH2,NCOA7,LSS,ASPRV1,MAP6,AQP11,MBD1,MEIS2,MID1,CD200,MSR1,MXI1,MYO7A,RTL5,MYT1,CCDC13,NPTX1,NUMA1,ODF2,P2RY1,PCDH9,PCSK5,PDE2A,PDE3B,BEST3,NALCN,CCSER2,RETREG1,MAPKAP1,CDIP1,SDK2,MBOAT7,EPB41L4B,SLC36A4,POLG,PPM1B,CRLS1,PTPA,PPP2R5C,PPP3CB,PRKAB2,RAB39A,PRKCZ,MAPK10,MASP1,SIDT1,SNRK,MDGA2,PIGG,PLPPR1,NCR3LG1,PXK,ZSCAN32,PTPRO,ZSCAN2,RAB5B,ACSS3,CCDC40,RALGDS,SUSD4,NWD1,ARID4A,RADX,SLC6A15,TRIM68,RET,FIGN,RGS3,RGS12,RIC8B,TMLHE,EXD2,ALG9,ROBO2,ELP2,CCDC102B,EPHA10,ARMH4,ATP8B4,ACER3,LRRK2,ABCA11P,ATXN2,SCN8A,SCP2,SUPT20H,TRA2B,COPZ1,RASA3,SH3BGR,PPP1R9A,PPM1E,KIF16B,ASAP3,NTNG1,MAGI3,FBXO11,BCAN,ABLIM3,ZNF365,PEX26,SLC6A1,SLC8A2,SLC9A5,NAPB,LGI3,NAXD,ZNF667,SORCS3,CDK5RAP2,MBD5,FAM126B,USP33,SOX1,HECW1,MYCBP2,PEG10,NFASC,C11orf87,TAB2,SMOC1,SSTR1,EPB41L3,NKAIN2,SSPO,ZSCAN29,CEP68,DIP2A,ADHFE1,STXBP1,KAZN,CAMTA1,TAF6,EXOC7,DNMBP,CNTN2,ADGRL3,TMEM136,TCF7,AHCYL2,HIF3A,CCDC173,CYB561A3,PMS2CL,DICER1,TMEM121,KHDC1,C18orf54,AKTIP,TMEM9,ERCC6L2,C5orf64,TP53BP2,TPM3,RGMB,SMUG1,TRIO,TRPM2,SSBP2,CLHC1,SLC35A4,UBTF,PLEKHH2,TOM1L2,VIPR2,SLC13A3,XRCC4,ZBTB38,TMEM198,MAP3K12,EMSY,STOX2,SLC17A7,PCBP4,C12orf4,RGS7BP,UBE3B,FBXO36,ZNF248,TIGD6,RNF170,MSRB3,TTC7A,PIANP" MicroRNA hsa-miR-2113:mirSVR_highEffct hsa-miR-2113:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.20E-115 3.48E-111 5.03E-114 4.64E-113 283 1132 "RALGAPA1,ABR,ACADM,ACTN1,ADARB2,KLRC4,SLITRK1,ADCY6,ADD1,SLC12A5,SORCS1,BEND6,KLHL13,KCTD16,WDR35,OSBPL8,ADGRF5,PCDH10,SYT13,DPP10,LCORL,MAP4K3,PKP4,EPB41L5,GPAM,CASK,ARHGAP5,RGS20,LINC00173,NUMB,ATP1A2,EIF4G3,ATP1B3,B3GALT2,NOL4,DPY19L3,ADAM23,TTLL9,ADGRB3,SEC11C,GPR146,SYNJ1,CACNA1B,CACNA1E,CACNB4,CAMK2G,SLC25A14,SPAG9,CDH2,MAGI1,SYNPR,TJP2,C4orf33,AKAP6,ABI3BP,TBPL1,ZNF521,ZNF385A,CRHBP,HAPLN1,ANKRD44,CS,CSNK1E,SOCS5,FAM169A,ST18,DOCK4,HDAC9,RIPOR2,ZFYVE16,LIN54,BRINP1,AIF1L,DBN1,DCC,ELMO1,CEP170,MAGI2,NTM,DYRK1A,GOLT1B,EBF1,EDIL3,EDN1,ATL1,ANKRD46,SUGP2,AASS,EIF4G2,STARD3NL,OLIG2,EPS8,NCALD,RTN3,EYA1,MRVI1,ABCA8,SH3YL1,TAOK3,SLC9B2,FER,FGF12,FGF13,POLK,SYNCRIP,SLC37A3,NELFCD,SORBS1,UFM1,ZNF605,STAU2,TMEM151A,TBR1,AP4B1,FYB1,GALNT15,KIAA1841,MSTN,ARFIP1,AHDC1,MALT1,RAB30,PCDH11X,AIFM3,ZNF638,FERMT2,GPD2,PRUNE2,PLCD4,GRIK2,GRM1,GRM3,LINC00839,ZBTB49,GUCY1A2,GPR45,HLF,HMGB1,HTR2A,IDH3A,RBPJ,USP54,ZNF678,LRRTM3,KCNC2,KCND1,KCND2,KCNH1,KCNN2,STXBP5,HECTD2,LRP1B,MEIS2,MITF,MSRA,MXI1,NDP,IDNK,NRCAM,IGSF11,OMG,PCSK5,NLGN3,PIK3C2A,ZNF655,CCSER2,RETREG1,MTRF1L,PURG,PDZRN4,PMP2,TRHDE,STRN3,SH3KBP1,POU3F2,PKN2,EPDR1,HYDIN,RELN,MDGA2,CNTLN,BDNF-AS,OXR1,ARID4A,CRTAC1,GTDC1,RPRD1A,CARF,ROBO2,FBXW7,ATP8B4,SGSM1,CNTNAP3,KCNIP1,FAM192A,SEMA6D,SATB1,CSRNP3,ATXN1,SCN3A,SCN8A,SEC14L1,SOX6,KIF16B,CPEB3,SHC4,SLA,RUFY2,SEPHS1,CCDC88A,SLN,SORCS3,LIMCH1,RIMS1,ANKFN1,MYT1L,TNIK,KDM4C,KIF1B,ZBTB43,RBM26,LMO3,POGZ,STOX1,EPB41L3,ERBIN,MPRIP,RGL1,SULF2,STXBP1,NECAB1,FNDC9,SYT1,MMS19,ANKRD12,KAZN,SEMA4A,CAMTA1,TAL1,ALG1,ADGRL3,TMEM136,TCF4,TRIM2,TCF12,WDR7,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,GZF1,ACTR6,KAT6B,TPD52,SYNPO2,TRPC3,ZMYND8,FNDC5,TMEFF2,UGT8,VSNL1,RBFOX3,RICTOR,ZBTB14,TRIM9,ZBTB38,UPF3A,PMEPA1,CSDE1,RNF103,NAV3,LINC00632,CAB39L,WIPF2,SLC17A6,C12orf4,KAT6A,DPF3" MicroRNA hsa-miR-135b:mirSVR_highEffct hsa-miR-135b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.40E-115 3.59E-111 5.18E-114 4.78E-113 310 1354 "ABAT,ADAR,GALNT13,PLEKHH1,PTCHD1,KIDINS220,INTS2,MTUS1,LRRC7,ALCAM,ARHGAP20,LRCH2,ANK3,PHF12,PKP4,ANXA7,CNTNAP1,APC,API5,TMEFF1,ZFYVE28,ARNTL,RGS20,PDE8B,ASPH,NUMB,ATP1A2,ATP2B3,CADM3,N4BP2L1,ADAM23,BACH1,DST,ARHGEF7,CA12,CACNA1D,CACNB4,CALM1,KALRN,PTBP2,CAMK2G,CAPN3,RUNX1T1,ZNF501,LDB2,ARHGEF2,KCNAB3,L3MBTL4,LOC730101,UBE2L6,SOCS6,QKI,ARHGEF6,CNTN1,FAM149A,ZFP28,PREPL,ENTPD4,HAPLN1,RGS6,ARHGEF10,MICAL2,CSNK1G3,ATRNL1,VCAN,SLITRK5,UBXN2A,CFAP61,CTNND1,NRSN1,BOC,ARHGAP32,FRMPD4,LONRF1,KIAA0586,PITPNC1,JAKMIP2,MYEF2,CEP170,DDX46,FAM107B,CHRDL1,EXOG,RAB39B,PDCD6IP,EBF1,EDIL3,EDNRA,ANKRD46,SGK2,HIPK3,YAF2,PHF20L1,GOLGA7,PLEKHA1,CERCAM,MRNIP,SRRM1,EFS,TMEM74,EYA1,MRVI1,F8,CLVS1,FAM198B,ZIC4,SCML2,FDFT1,FGFR1,POLK,HPCAL4,CAP2,SYNCRIP,PSD2,NBEA,UFM1,STAMBP,ATP2C1,ZNF605,KHDRBS3,STAU2,TVP23A,OGA,GABRA2,ERAP1,CPLX2,GCNT2,HEPN1,GHR,BRD8,RAB30,GLRB,GNG3,FERMT2,GPM6B,RAPGEF4,GRIA4,NR3C1,PSIP1,HPS5,AGBL5,ZDHHC15,OPALIN,IRF8,USP54,LIX1,IL6ST,ZNF385B,ITGAV,JAK2,KCND1,KCNMA1,STMN1,PIK3AP1,MBD1,SYT9,MDM4,MEIS1,MOBP,MRPL42,ZNF92,MTTP,MYO6,NAP1L2,NEFM,NODAL,NPTX1,HCN1,OPHN1,PBX1,PCDH9,PDCD2,PDE3B,GDAP1L1,ANLN,PLP1,PCDH18,PURG,STRN3,SCHIP1,PRRX1,SDK2,DRAM2,MINDY2,PPM1B,CRLS1,PPP2R5C,CEP41,PKN2,GDPD1,MASP1,RELN,LRRC49,APTX,MDGA2,PTK2,ZSCAN32,PPP2R3C,RAP1GDS1,ZCWPW1,ENOX1,VEPH1,RDX,ERI2,RFX5,SLC25A36,ROBO1,CCDC25,RORB,PCMTD2,ATAT1,FAM182A,TMEM156,MIR124-2HG,SCN2A,PPM1E,ASAP3,NTNG1,ST3GAL3,ABLIM3,SLA,ZNF365,SLC6A9,ZNF430,SLC8A1,CCDC88A,SLC15A2,SPHKAP,ZFP1,ZNF667,SMARCE1,RIMS1,MBD5,SNRPN,PALLD,DOP1A,PDZD2,ZCCHC24,BDP1,HECW1,STOX1,ZNF302,NXT2,SEPT8,RGL1,DIP2A,KANK1,STXBP1,ARC,POPDC3,MTCL1,CNTN2,TMEM136,KLHL4,ANO4,ATMIN,CUX2,TCF7L2,WASHC4,WDR7,SYNE1,PMS2CL,SIRT1,CRB1,C18orf54,ITGB3BP,SLC44A1,TMEM9,BHLHB9,ERCC6L2,FAM124A,C5orf64,KAT6B,NPL,SYNPO2,TRPC1,UGT8,DNAJC12,VLDLR,TBC1D15,WIPF1,XRCC4,ZNF708,ZNF24,TRIM9,FMN2,NDRG4,ZNF138,TMEM237,FTSJ1,ZFAND5,INTS3,EMSY,DNALI1,EVI5,STMN4,RNF103,TMEM163,MVB12B,PLSCR4,DOCK8,ST7,RTN4,PAK5,CAMK1G,IFT88,NETO2,RNF146,SLC4A10,SENP7" MicroRNA hsa-miR-655:PITA hsa-miR-655:PITA_TOP PITA 8.16E-115 4.58E-111 6.61E-114 6.08E-113 237 789 "ACLY,SLITRK1,CCDC85A,ADD1,ADD3,USP31,PWWP2A,AP2A1,PCDH19,HACE1,LRRC7,FAM135A,LRCH2,MAP4K3,APC,EPB41L5,GAS7,BCAS1,APP,AQP4,TMEM263,CASK,TMEFF1,ARHGAP5,ASCL1,CAPRIN2,NCOA1,DDX3Y,EIF4G3,ATP2A2,ATP2B1,B3GALT2,DCAF5,SYNJ1,ARHGEF7,CACNB2,CALM1,CANX,RUNX1T1,CDC42,CDH2,CCPG1,NUMBL,SOCS6,CHN2,QKI,HECTD1,MAP4K4,NIPBL,CNR1,ZNF521,SLC35F1,PHACTR3,SLITRK5,ERC2,PLCXD3,USP6NL,DOCK4,ZFYVE16,COPS7A,MAGI2,ZC3H11A,RHOBTB1,WDR20,DMD,CPEB2,SLC12A6,DYRK1A,EBF1,SNX29,HIPK3,SEMA3D,YAF2,MBNL2,TENM1,EML1,PAN3,EN2,VPS13B,EPB41,EPB41L2,SEZ6,SRRM1,ETV1,EYA1,ACSL4,UBE2E3,MEX3B,PDLIM5,STAU2,MEGF10,GAB1,CHL1,GABRB3,ARFIP1,GPR162,SESN1,AHDC1,GFRA2,PCDH17,SPIN1,GLRB,PCDH11X,STARD3,FERMT2,GPD2,GRIA4,RFFL,GRM2,GRM3,FAM19A2,PTPN5,KAT7,ZBTB49,GUCY1A2,ADAMTS6,KLF12,ELOVL5,HMGCR,AGFG1,C5orf24,KCNA4,KCNJ3,IPO5,STXBP5,KTN1,AQP11,MATN3,MBD1,CHIC1,LRP1B,MEIS1,MID1,MITF,CCDC80,MYO5A,NEFM,NEUROD1,NF1,HCN1,OPA1,CNTN3,PDE4B,GPR85,CDK14,PIK3C2A,PIK3R1,STRN3,LRRN3,PPP3CA,CEP41,MAPK9,DIRAS2,SNRK,PTCH1,ELOVL2,PTPRG,FAM120C,PTX3,MARCH1,RAB5B,RBBP6,KHDRBS2,RDX,RGS4,RGS7,SPIN3,WLS,RTN1,NCBP3,SATB1,FNIP1,SFPQ,CPEB3,NTNG1,FBXO11,SLITRK3,ST3GAL3,SLC1A2,WDR47,SLC6A1,RAB3GAP1,TRIM67,SMARCE1,SOX1,SOX2,ZCCHC24,ZNF423,CDK19,RBM26,SRPK2,SSTR1,NKAIN2,KANK1,ZC3H4,PRRC2C,ANKRD28,SYT4,CAMSAP2,ADGRL3,AGTPBP1,FBXW11,ATMIN,TCF4,SATB2,TRIM2,RPGRIP1L,DOCK9,AHCYL2,DICER1,ZFPM2,DDHD1,HEY2,CSMD1,RBFOX2,TRPS1,ZMYND8,HEPACAM,VSNL1,WIPF1,XPO1,ZNF711,ZNF23,REEP1,ZFAND5,WNK1,PMEPA1,CADM2,NAV3,RGS7BP,GOPC,FAM13C,HNRNPA3,JMJD1C,PIANP,RNF146,ST8SIA2" MicroRNA hsa-miR-4256:mirSVR_lowEffct hsa-miR-4256:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-114 7.70E-111 1.11E-113 1.02E-112 301 1282 "ASPHD1,CSMD3,KLHL32,GALNT16,ADD2,SORCS1,WDR35,OSBPL8,BCAR3,FAM135A,SYT13,AMPD3,ZFAT,CDC42BPA,CCDC146,CNIH2,PARG,EPB41L5,DGKZ,PHYHD1,BCAS1,IGDCC4,MARK4,ASPH,DACT3,MTMR9,B3GALT2,BBS2,RGS11,DNAJC27-AS1,ST3GAL5,CASTOR3,NIPA1,OSGIN2,BTRC,THSD7A,CALM1,KALRN,CBR1,CLDN10,USP6,INA,LRBA,CDC42,CDH18,LOC730101,DLGAP2,IGFN1,CHGB,SOCS6,CHRNB2,ARHGAP22,NRXN3,CLU,FBXO7,NIPBL,SLC35F1,CREB5,CSF1R,FEZ1,RIMS4,APPL1,PHF14,EDRF1,ECE2,DOCK4,EARS2,SPOCK2,PLEKHM1,KIAA0753,SPOCK3,NTM,DLG3,HS3ST4,HS3ST2,USP3,DOCK2,ACOT8,DTNA,DNAJB6,DYRK1A,ABCC5,E2F5,SEZ6L2,EDN1,PHC2,HIPK3,SEMA3D,KLHL5,TMTC1,YAF2,PHF20L1,TMEM132E,AASS,TENM1,PLEKHA1,EPB41,EPHA5,RASL12,F5,TAOK3,EFEMP1,MED12L,OLFM1,FGFR1,SEC23B,SYNCRIP,SEMA4D,TMEM107,UFM1,ATP2C1,ZNF605,DLL3,ZMAT1,STAG2,MEGF10,CHL1,HBS1L,FAM120B,ZMYND11,B4GALNT1,ARPP21,ZNF274,NEK6,LRRC37A6P,ALDH1L1,NFU1,MMADHC,GFRA2,HEPN1,RND1,DBF4,SPIN1,ZNF638,HTATSF1,GNG4,LILRB4,GPD1,STON1,GPR34,RAPGEF4,GRIA2,WIF1,IRAK3,LINC01102,GABARAPL2,SYNPO,HSD17B1,SMAP1,GAREM2,USP54,SCIN,LIX1,KCNA6,KCNK2,KCNN2,IPO5,KTN1,INSYN2,SYTL4,LSS,MAP4,MBP,MDM4,N6AMT1,CTNNA3,MXI1,MYT1,NAP1L3,ZC3H12B,CCDC13,NF1,ALDH1L2,NODAL,NOVA1,SLC11A2,SMIM11A,TBC1D25,GPR88,OGDH,OPCML,PAH,PBX1,PDCD2,PDE1A,PDE4D,PDE1B,SLC10A4,PFKFB3,PFKFB4,SEMA5B,PIK3CD,NLE1,PLP1,PRIMPOL,RETREG2,FA2H,POLG,SH3KBP1,POU6F1,PPM1B,PPP1R1A,PKIA,PRKCB,PKN2,MAPK4,HYDIN,WBP1L,PIGG,CNTLN,PLPPR1,STK32A,PTPRB,PTPRE,ACSS3,SLC25A41,RASGRF2,REV3L,RGS7,RNASE1,ROBO2,TMEM100,EPHA10,FBXW7,CCDC112,SCP2,ITSN1,ASAP3,HKDC1,AMBRA1,R3HDM2,ST6GAL1,ZNF365,SMTN,SLC8A3,SLC14A1,SMARCA4,UNC80,USP33,TNIK,FNBP1,EMC1,TEX2,PEG10,KIF1B,TSPYL2,TROVE2,COLGALT2,MPRIP,ELOVL4,ABCC8,SYP,TACC1,MTCL1,DNMBP,TBX15,TCF4,ZFP90,CUX2,TCF7,WASHC4,USP22,PCDHB9,ARHGEF12,SIK3,DAAM2,RASD2,NPL,SMUG1,ELP5,ZMYND8,DCBLD1,TSC1,TUB,CADM1,FAM155A,UGT8,PITPNB,FLRT2,FAM181B,VLDLR,LAT2,NSD2,ZBTB14,ZIC1,ZNF540,AGMO,FMN2,GPR158-AS1,ZBTB38,TMEM237,POLR3H,SYNC,CA10,PRDM10,RNF103,HPS4,MDH1B,FIP1L1,FAM47E,ZNF248" MicroRNA hsa-miR-3153:mirSVR_highEffct hsa-miR-3153:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-114 8.23E-111 1.18E-113 1.09E-112 314 1392 "ASIC1,METAP1D,ARID1A,FMNL2,AXIN2,BRAP,SORCS1,SPOP,ALCAM,ARHGAP20,MARCH4,LRFN1,EP400,APLP1,MIER1,CADPS,ASPH,ATP1A2,ZNF582,N4BP2L1,ATP6V1G2,RGS9,SYNJ2,FUBP1,JAZF1,CACNA1G,BTRC,CACNA1A,THSD7A,KALRN,CANX,VXN,NFS1,CBLN1,ZNF501,CCNH,MTMR7,LRBA,CDC42,LRRFIP1,LARGE1,GPR37L1,SRSF11,CHN2,SYNPR,EPS15L1,RAB33A,KIAA1549L,CLTA,FAM189A2,ARHGEF6,CNTN1,COL11A2,MAGED1,GAL3ST1,RTTN,TOGARAM2,ZFP28,CNRIP1,ENTPD4,CRMP1,ANKRD44,TRIM69,CS,NCAN,DZIP3,ERC2,PHF14,CTNND1,NRSN1,ZSCAN23,GAPVD1,IST1,TMEM170A,ARMCX4,ZEB2,MYEF2,HP1BP3,CEP170,DDX46,NTM,AK5,DMD,DMTF1,DPP6,DRD1,DSCAM,EDN1,SGK2,FRY,FSD1L,YAF2,EFNB3,PHF20L1,EGFR,BSCL2,PAN3,DCTN4,RTN3,MRVI1,EZH1,F5,RPS6KC1,PTK2B,CORO2B,DLC1,ZSCAN30,STRADA,TESK2,SLC9B2,OLFM1,FGF11,IQCG,TPK1,ST6GALNAC3,PHYHIPL,STAG2,MEGF10,GABBR1,GABRA1,GABRA2,GABRB1,BRPF3,FAM120B,JPH4,GAP43,TMEM8B,MTHFD2,DISC1,GGT7,PPARGC1A,CBX1,INSM2,GNAL,GNAS,LNX1,TDRKH,GRIA2,PLCD4,GRIK1,NR3C1,GRM5,GRM7,GSTT2,GUCY1A2,ADAMTS6,IGSF21,ATXN2L,ARHGAP36,NEGR1,LRRC75A,ITIH2,KCNJ3,KCNK2,KCNMA1,STXBP5,HECTD2,FGFBP3,MARK1,LYPLAL1,MAT2A,MSI1,CTNNA3,MYH6,RTL5,PABPC1L2A,NEFH,NEUROD1,NF1,NOVA1,DNHD1,SLC11A2,NUMA1,SETD4,OLR1,CLDN11,PCSK1,PDE2A,PDE3B,PDE4B,GDAP1L1,NALCN,FAM218A,FTO,EPN1,PURG,MAPKAP1,LRP12,PSAT1,MBOAT7,SH3KBP1,POLR2F,POU3F4,IRX1,PRKACB,PKIA,HYDIN,RELN,BCAS3,SNRK,WDR25,PTN,PTPRB,PTPRO,PEX2,RAB5B,PID1,SH3TC2,FAT4,RAP1GDS1,ZDHHC14,GAL3ST4,ZYG11B,DPF2,RET,RNF220,RPRD1A,EXD2,RAVER2,CARF,ATP8B4,ATAT1,RTN1,NCBP3,SEC14L1,SFPQ,ITSN1,SH3GL2,CPEB3,MAGI3,SLITRK3,ST3GAL3,RPH3A,ARHGEF40,SLC9A5,NAPB,ZFP1,SMARCC2,INTS9,LIMCH1,RIMS1,MBD5,ANKFN1,SNRPN,PDZD2,TNIK,SOX5,KDM4C,KIF1B,NPAS3,LMO3,C11orf87,SRPK2,ZC4H2,TTBK2,ADHFE1,PHLDB1,KANK1,GANAB,AJAP1,FGD4,ARHGEF9,TMEM150C,SYN2,ANKRD28,MMS19,TACC1,TMEM136,TBX15,RPGRIP1L,PCDHB4,PUM2,FRYL,RNF175,LEFTY2,ZMAT3,GZF1,TIAM1,BHLHB9,ERCC6L2,TNR,TPM1,STXBP4,ZMYND8,DCBLD1,RFTN2,ZKSCAN5,TMEFF2,CADM1,GORASP1,SLAIN1,ZNF709,VLDLR,WIPF1,GUSBP1,SLC13A3,LGI4,SF1,ZIC2,ZNF32,FMN2,SLC26A10,MKRN3,DHX33,CA10,PARP6,PRDM8,PCDH15,NAV3,GOPC,AMN1,ST7,VANGL2,NHSL1" MicroRNA hsa-miR-589:mirSVR_lowEffct hsa-miR-589:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-114 8.58E-111 1.23E-113 1.13E-112 332 1549 "ABAT,DGCR6,CSMD2,ADAR,PLEKHG5,GALNT16,ADCY2,MTA3,AP2A2,PCDH19,RTL9,CC2D2A,SEMA6A,FAM135A,AMPH,BIN1,CCDC146,ANXA7,APBB1,UPRT,ALS2,CACHD1,SHTN1,CPNE5,DNAH17,CAPRIN2,RASL11B,CCDC181,ATP2B2,N4BP2L1,ATP6V0A1,BACH1,SNAI3-AS1,LINC00847,SYNJ1,C1QC,CACNA1E,LURAP1,CALM1,CAMK2D,HIP1R,MAP7,CBR1,CCK,SLC16A4,TMEM257,NEURL1,ZMYM4,CDH18,MAGI1,TIGD7,DIS3L,ADGRG1,CHRM1,NRXN3,KIAA1549L,STOML1,NGEF,FAM149A,AKAP6,SUMF2,COL9A1,ACBD5,SLC35F1,CREM,RBM39,SLC32A1,GDA,SUSD5,CST3,CMTM5,PLCXD3,PNPLA8,CTNND2,ECE2,CCDC144A,ARHGAP32,GAPVD1,SNPH,MATR3,DGKG,SPOCK2,DNAL1,ARMCX2,ZBTB24,TMEM130,DDX46,POM121,RHOBTB1,SV2B,DLG2,DLX1,HS3ST4,DMPK,USP3,CPEB2,DOCK2,DMTF1,SLC12A6,DRD1,DYRK1A,USH1C,EDNRB,SYT15,TMTC1,FAM13A,MRO,KMT5B,EGR3,EIF4G2,PLEKHA1,EN2,EPHA5,GPHN,RAB9B,EFS,MRPL37,RRAGB,SIRPB1,ADGRV1,F3,FER,FOXO3,SEMA4D,TPK1,ARFGAP2,ATP6V1H,ATP2C1,ZNF605,GABBR1,GABRA2,GABRB1,GAD2,BRPF3,FAM120B,SALL3,ZNF274,GHDC,NCKAP1,CPLX1,DNER,NEU3,SULT1C4,GFAP,KIRREL3,COPS8,MSL3,LUZP2,DCLK2,GPD1,GPM6B,ATF7,TDRKH,GPR19,RAPGEF4,GRIA1,GRIA2,C1QL4,GRIA4,GRM7,LINC01089,RNF165,ZBTB49,ZBTB45,MAEL,PADI2,ZHX1,FRMD3,HSP90AA1,LRRC25,LRRCC1,USP54,IGSF1,SCIN,LIX1,ITGAM,C2CD4C,METTL21A,KCNJ10,KCNJ16,KCNK1,KCNK2,KCNN2,LIFR,C2orf80,MAP2,MARK1,SHC3,MEIS1,MOG,ERICH3,JAKMIP3,N6AMT1,MTR,MDGA1,MYO6,MYO9A,HNRNPM,NEFM,NFIX,NODAL,NOVA1,NTRK3,IGSF11,OCRL,SNTG1,PAK3,PCMT1,PDE2A,PDGFRA,GNG2,BEST3,PFKFB2,GDAP1L1,FAM216A,PLP1,POU3F2,POU6F1,PPP2R5E,PRKAB2,PRKCZ,MASP1,SIDT1,PIGG,CNTLN,PTCH1,STK32A,ZIK1,PTPRD,PTPRE,PEX2,NKAIN1,RAB3A,ATG16L1,RASGRF2,RDX,SLC6A15,RFX2,RFX4,RGS3,RGS12,ALG9,ARMC5,RAVER2,GSTCD,TMEM100,LRRK2,ZNF568,SCN3A,SCP2,SOX6,NLGN4Y,ITSN1,FERMT1,HKDC1,MAGI3,WDR37,FAM81A,EPN2,WDR47,RUFY2,SLC6A1,SLC11A1,SLC15A2,IGSF9B,INAVA,MBD5,SCN3B,SON,DOK5,RBM26,NFASC,CLSTN2,CAMTA2,ITPRID2,SSTR1,ADHFE1,JMJD6,ZC3H4,PLCB1,KAZN,CAMTA1,PDLIM2,UNC5D,FBXW11,SMG6,KLHL4,ZFP90,SZT2,PCDHGA11,HIF3A,CCDC173,DICER1,SPX,AP4E1,HEY2,TNNT1,RBFOX2,RGMB,ZNF346,RUNDC3B,TRPS1,RUSC1,TSN,ANO5,TTPA,TUBB1,RPL7L1,CLEC2L,DNAJC12,SLAIN1,OSBP2,USP1,MEAF6,CCDC14,NSD2,GUSBP1,XRCC4,ZNF540,POLR3H,MEIS3,CADM2,PRDM2,SLC38A1,CSDE1,RNF103,HPS4,PCDH15,PARP11,UBE3B,CASC15,DPF3" MicroRNA hsa-miR-148a:mirSVR_highEffct hsa-miR-148a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.61E-114 9.05E-111 1.30E-113 1.20E-112 285 1152 "CLK4,FAM43B,TMEM132B,CCDC85A,SLC12A5,AP2A2,HECW2,KCTD16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,MARCH4,PCDH10,PITPNM2,AMPD3,USP28,APBB1,MIER1,ASPH,NCOA1,ATP1A2,STX16,NOL4,ADAM23,ADGRB3,CDK5R1,DST,SYNJ1,SYNJ2,GPC2,LURAP1,CABP7,CANX,SYT6,CAST,CCKBR,USP6,MAGI1,NOG,CFL2,SRSF11,B4GALT6,PLAA,QKI,AKAP7,ARMC8,FAM149A,ABI3BP,CHD1L,CLOCK,SEC24C,FEZ2,ATRNL1,ERC2,CFAP61,CTNND1,ST18,RUBCN,BOC,GAPVD1,MATR3,KIAA0586,TMEM170A,YTHDC1,ZNF804A,C8orf34,HEPH,SMG7,SNAP91,SACS,NTM,WDR20,DLG2,DLG3,RAB39B,DMPK,DNM2,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,COPS4,ELAVL2,TNK2,RTN3,TLR7,F3,ACSL4,SCML2,FCGR1A,FER,MED12L,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,NPTN,ATP2C1,TVP23A,NEURL4,STAG2,DKK3,HBS1L,ZNF274,GAP43,C15orf41,DISC1,KIAA1841,DNER,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,INSM2,RAB40B,GPM6A,PCLO,GRIA1,DIDO1,RNF165,KAT7,MFSD2A,LINC01551,HPS5,TNFAIP8L3,ELOVL5,HPSE2,IGSF1,LIX1,KCNK2,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,C2orf80,MAT2A,MATN3,MBD1,TM6SF1,PPM1L,MITF,ZNF680,NDP,NEUROD1,NF1,CNOT4,DNHD1,NPTX1,NPTX2,PCDH9,PDE1A,PDE1C,PDYN,SLC10A4,PFKFB2,CDK14,GDAP1L1,PIK3C2A,JAKMIP1,PLIN1,TRHDE,EPB41L4B,POU3F2,PPM1B,TATDN3,PTPA,PPP3CA,KANSL1,RASGEF1B,RAB39A,MAPK7,MAPK10,GRAMD1C,SNRK,MDGA2,MTMR10,PTHLH,PTPRD,EML5,PTPRN,PPP2R3C,TMEM255A,SH3TC2,FAM184A,RBBP6,DPF2,SLC25A36,RNASEL,ZFHX4,PNMA8A,ROBO1,ROBO2,RORB,ELP2,PRR5L,YJEFN3,SATB1,LRRTM4,SELL,NLGN4Y,CHD9,FBXO11,FNDC3A,ABLIM3,FAM81A,SLC1A7,BTBD3,WDR47,RUFY2,SPHKAP,SMARCA4,LMBRD1,SNRPN,USP33,SON,SOX5,SP4,ZC3H13,CDK19,SRPK2,ITPRID2,SMOC1,EPB41L3,NKAIN2,NCDN,RGL1,FGD4,VPS13A,SYT4,ATP11A,MTCL1,DDHD2,UNC5D,ZEB1,RPGRIP1L,TCF12,WDR7,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,FBXL16,NACC2,TJP1,TNFRSF1B,TNS1,TPM1,TPM3,TRPC3,CADM1,UBE2H,BCL2L13,P2RY12,ZNF24,SPIRE1,SYNC,LINC02210,STOX2,MDH1B,PCDH15,C12orf4,EPM2A,ST7,RTN4,PHTF2,FXR1,JPH3" MicroRNA hsa-miR-3126-3p:mirSVR_lowEffct hsa-miR-3126-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.65E-114 9.25E-111 1.32E-113 1.22E-112 309 1350 "TTYH1,KCNH8,EMILIN3,KDM5D,ADCY6,CCDC85A,ADD1,SORCS1,UNC5A,PWWP2A,KIDINS220,OSBPL1A,LRRC7,ALAD,MRTFA,OGT,PI16,SMIM29,SLC7A14,ARSF,ASPH,DACT3,BRINP2,ATP2B3,ADGRB1,BARD1,SEC11C,BCHE,DNAJC27-AS1,DCAF5,NRP2,AP1M1,OSGIN2,DDR1,CAST,ARHGEF25,CCNH,USP6,DGKI,REPS2,ZBED1,ZMYM4,NUMBL,CHN1,CHRM1,SYNPR,IGFBP7-AS1,FBXO7,FAM189A2,DNAJB5,AKAP6,MAGED1,MYRIP,CHD1L,GDA,TRIM69,FEZ1,ARHGEF10,OSBPL3,SUSD5,CNTNAP2,DZIP3,KIAA0040,CMTM5,PNPLA8,GREB1,CYBB,RIPOR2,PHF19,LONRF1,SCRN1,ELMSAN1,ZEB2,RUSC2,KLHL3,BLOC1S6,LYPD1,DDX46,SNAP91,SPOCK3,SRGAP3,RABGAP1L,WDR20,KBTBD11,EXOG,GRIN3A,DMD,HS3ST2,NYAP1,NR1D2,DOCK2,SLC12A6,DRP2,USH1C,SNX29,EDNRA,ATL1,HIPK3,EEF1D,YAF2,PHF20L1,EGFR,EGR3,KCTD3,ELAVL3,CALCRL,RASGRP2,EPHA5,ENPP6,RABEPK,ERBB2,ZNF549,ETV1,KATNAL1,EZH1,DLC1,CEP78,FCGR3A,ZNF589,AMOTL2,UBE2E3,FOXM1,FLNC,ANKFY1,USP16,PDLIM5,DACH2,KBTBD12,NRG3,DKK3,GABRB1,FAM120B,ZNF274,DNER,MYOZ2,GATM,NEU3,FREM1,PCDH11X,STARD3,ATF7,NUDT21,GRIA1,PRDM5,GRM7,LINC00839,PSIP1,ADAMTS6,MAP4K5,WIF1,PADI2,FRMD5,HNRNPK,CELF5,SMAP1,MYLK2,RBPJ,LRRCC1,DISP2,SCIN,IL6ST,IL11RA,KCNK2,KCNMA1,KIF5A,KIF5C,A1BG-AS1,HECTD2,MAN2A2,MAP4,MAT2A,MEIS2,KITLG,MID1,MOBP,MOG,CD200,MRPL42,MYBPC1,MYO9A,NF1,NOVA1,ZDHHC22,SNTG1,CNTN3,DPY19L2P2,ETFRF1,PIRT,ENPP2,GNG2,TRHDE,RC3H2,ING3,PPM1B,LRRN3,PPP3CB,RANBP3L,EPDR1,GRAMD1C,SIDT1,CNTLN,PLPPR1,MTMR10,STK32A,PTPRB,PTPRD,PTPRG,PTPRO,C1orf109,PTX3,RAB3A,CEP97,FAT4,RASGRF2,ZYG11B,RFX5,RGR,CCDC82,KIRREL1,RPS6KA2,LRRK2,KCNIP1,AP1AR,MIR124-2HG,LRRTM4,SOX6,CASC3,GALNT10,STUM,SCAF8,NLGN4Y,FERMT1,FHOD3,NLGN1,CTXN2,ZNF365,SLC2A5,SLC6A8,SLC6A9,RAB3GAP1,KBTBD4,TMEM132D,SLC22A4,NAXD,SORCS3,IFT122,ANKRD36,RIMS1,CMTR2,SNRPN,KIF21B,UNC5B,ZNF423,RBM26,NFASC,NKAIN2,ZSCAN29,ELOVL4,TTBK2,KANK1,PRRC2C,PLCB1,COBL,SLC37A2,TAL1,TBCEL,SMG6,ANO4,CUX2,WDR7,SYNE1,RALYL,CYB561A3,DICER1,SIRT1,ZFPM2,GPR161,TGFBR3,SLC44A1,MTMR14,ERCC6L2,DAAM2,TPD52,AMACR,ZMYND8,PPIL6,TSN,TSC1,PRR18,FAM181B,PLEKHH2,WIPF1,GUSBP1,ZNF711,ZNF74,GPR158-AS1,SLC26A10,ZBTB38,REEP1,ZFAND5,DHX33,INTS3,RGMA,KAT6A,CAMK1G,FAM219B,TRAM2-AS1,MSRB3,FAM198A" MicroRNA hsa-miR-29a-3p:TargetScan hsa-miR-29a-3p TargetScan 1.66E-114 9.30E-111 1.33E-113 1.22E-112 253 906 "ASIC1,NCKAP5,ACTN2,CCDC85A,ADCYAP1R1,CDC7,GRAMD1B,RNF150,OSBPL6,PITPNM2,CDC42BPA,ANK1,ANK3,PARG,APC,GAS7,GPAM,DGKD,ALS2,AQP4,ARRB1,DDX3Y,ATP2B2,MTMR9,N4BP2L1,BCL2L2,BCL7A,PROM1,JAZF1,LDLRAD4,MMD2,CACNA1A,CACNA1B,DIRAS1,CAMK2G,RUNX1T1,FMNL3,INA,REPS2,CDC42,L3MBTL4,DLGAP2,CFL2,FOXN3,RAB3C,CNOT8,KIAA1549L,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,IFFO1,CPS1,CREB5,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,CTNND1,NRSN1,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DLG2,FAM57B,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELAVL4,ELN,EPB41L1,MTSS1L,ANKRD13B,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,GAB1,GABRB1,ILDR2,FAM184B,FAXC,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,EML4,GPR37,CACFD1,RNF165,BVES,HAS2,KLF12,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,C5orf24,IGSF1,KCNC2,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,LDLRAD3,MEST,SCAMP5,MMP16,MOG,MXI1,MYCN,NASP,NFIA,NFIX,OXTR,KCNK10,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK8,MAPK10,CNNM2,PTHLH,PTPRD,EML5,PEX5,NKAIN1,MARCH1,CEP97,RAP1GDS1,BSDC1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,PAQR6,KCNIP2,ATXN1,SCN7A,HSPA4L,PPP1R9A,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,SCN3B,HECW1,ERC1,PEG10,NPAS3,C11orf87,LARP4,FCHO1,ELOVL4,FGD4,PRRC2C,ADAMTS17,EXOC7,CAMSAP2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,HEY2,DAAM2,FAM124A,RBFOX2,FNDC5,HEPACAM,CLEC2L,AMOT,EML6,DPYSL5,ADAMTS9,NAV3,NAV2,GOPC,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-29c-3p:TargetScan hsa-miR-29c-3p TargetScan 1.66E-114 9.30E-111 1.33E-113 1.22E-112 253 906 "ASIC1,NCKAP5,ACTN2,CCDC85A,ADCYAP1R1,CDC7,GRAMD1B,RNF150,OSBPL6,PITPNM2,CDC42BPA,ANK1,ANK3,PARG,APC,GAS7,GPAM,DGKD,ALS2,AQP4,ARRB1,DDX3Y,ATP2B2,MTMR9,N4BP2L1,BCL2L2,BCL7A,PROM1,JAZF1,LDLRAD4,MMD2,CACNA1A,CACNA1B,DIRAS1,CAMK2G,RUNX1T1,FMNL3,INA,REPS2,CDC42,L3MBTL4,DLGAP2,CFL2,FOXN3,RAB3C,CNOT8,KIAA1549L,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,IFFO1,CPS1,CREB5,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,CTNND1,NRSN1,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DLG2,FAM57B,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELAVL4,ELN,EPB41L1,MTSS1L,ANKRD13B,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,GAB1,GABRB1,ILDR2,FAM184B,FAXC,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,EML4,GPR37,CACFD1,RNF165,BVES,HAS2,KLF12,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,C5orf24,IGSF1,KCNC2,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,LDLRAD3,MEST,SCAMP5,MMP16,MOG,MXI1,MYCN,NASP,NFIA,NFIX,OXTR,KCNK10,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK8,MAPK10,CNNM2,PTHLH,PTPRD,EML5,PEX5,NKAIN1,MARCH1,CEP97,RAP1GDS1,BSDC1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,PAQR6,KCNIP2,ATXN1,SCN7A,HSPA4L,PPP1R9A,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,SCN3B,HECW1,ERC1,PEG10,NPAS3,C11orf87,LARP4,FCHO1,ELOVL4,FGD4,PRRC2C,ADAMTS17,EXOC7,CAMSAP2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,HEY2,DAAM2,FAM124A,RBFOX2,FNDC5,HEPACAM,CLEC2L,AMOT,EML6,DPYSL5,ADAMTS9,NAV3,NAV2,GOPC,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-29b-3p:TargetScan hsa-miR-29b-3p TargetScan 1.66E-114 9.30E-111 1.33E-113 1.22E-112 253 906 "ASIC1,NCKAP5,ACTN2,CCDC85A,ADCYAP1R1,CDC7,GRAMD1B,RNF150,OSBPL6,PITPNM2,CDC42BPA,ANK1,ANK3,PARG,APC,GAS7,GPAM,DGKD,ALS2,AQP4,ARRB1,DDX3Y,ATP2B2,MTMR9,N4BP2L1,BCL2L2,BCL7A,PROM1,JAZF1,LDLRAD4,MMD2,CACNA1A,CACNA1B,DIRAS1,CAMK2G,RUNX1T1,FMNL3,INA,REPS2,CDC42,L3MBTL4,DLGAP2,CFL2,FOXN3,RAB3C,CNOT8,KIAA1549L,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,AKAP5,IFFO1,CPS1,CREB5,HAPLN1,NCOR2,ARHGEF10,OSBPL3,PITPNM3,ARHGEF4,CTNND1,NRSN1,FAM131B,HDAC4,KIF26A,DNAL1,ELMSAN1,DDX46,RHOBTB1,MTX3,DLG2,FAM57B,DPYSL2,DRP2,ARRDC4,FEM1B,HEYL,PLXNC1,GOLGA7,KCTD3,PLEKHA1,ELAVL4,ELN,EPB41L1,MTSS1L,ANKRD13B,CEP85L,SCML2,MED12L,MEX3B,FOXO3,ANKFY1,PSD2,C2orf88,CAMKK2,DOT1L,GAB1,GABRB1,ILDR2,FAM184B,FAXC,MSTN,FREM1,PCDH17,PPARGC1A,NTNG2,RAB30,FERMT2,EML4,GPR37,CACFD1,RNF165,BVES,HAS2,KLF12,ARHGAP36,BACH2,MIER3,HLF,HMGCR,HNF4G,NEGR1,MSL1,IGF1,C5orf24,IGSF1,KCNC2,KIF5A,LAMA2,LIMS1,MARK3,MAT2A,LDLRAD3,MEST,SCAMP5,MMP16,MOG,MXI1,MYCN,NASP,NFIA,NFIX,OXTR,KCNK10,PALM,PCDH9,PCSK5,PDE3A,ENPP2,GPR85,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PMP22,SCHIP1,EPB41L4B,PRKAB2,CEP41,MAPK8,MAPK10,CNNM2,PTHLH,PTPRD,EML5,PEX5,NKAIN1,MARCH1,CEP97,RAP1GDS1,BSDC1,REV3L,GTDC1,FIGN,NUDT11,CYB561D1,ROBO1,FBXW7,KIAA0895L,MCMBP,MAP6D1,PAQR6,KCNIP2,ATXN1,SCN7A,HSPA4L,PPP1R9A,PPM1E,CPEB3,MYO18A,CCDC88A,NAPB,ELMO2,BTBD7,LGI3,EPC1,MAPKBP1,MBD5,FAM126B,MYO16,KDM4B,SCN3B,HECW1,ERC1,PEG10,NPAS3,C11orf87,LARP4,FCHO1,ELOVL4,FGD4,PRRC2C,ADAMTS17,EXOC7,CAMSAP2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ENHO,CBX5,ASXL3,HEY2,DAAM2,FAM124A,RBFOX2,FNDC5,HEPACAM,CLEC2L,AMOT,EML6,DPYSL5,ADAMTS9,NAV3,NAV2,GOPC,JMJD1C,ADAMTS10,GAN,PRRT4" MicroRNA hsa-miR-372:mirSVR_highEffct hsa-miR-372:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.10E-114 1.74E-110 2.48E-113 2.29E-112 309 1353 "ABCF1,KIAA1211,PTCHD1,MTUS1,GPR158,KLHL13,AK2,C1QTNF3,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,STX16,DPY19L3,BACH1,DCAF5,CFLAR,ST3GAL5,ARHGEF7,MTMR3,JAZF1,CA12,CALB2,SYT6,VSTM2A,CBR1,AIFM1,SCARB1,ZBED1,MAGI1,CFL2,CHN2,TAOK2,IGFBP7-AS1,NRXN1,ABCG2,C4orf33,ARMC8,AKAP5,ABI3BP,ACBD5,IGDCC3,CNRIP1,ZNF385A,SLC35F1,CPS1,ENTPD4,CRHBP,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,DOCK4,HDAC9,TOX,ZNF804A,ZBTB24,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,RABGAP1L,HS3ST4,HS3ST2,DMTF1,DRD1,FAM78B,DNAJB6,E2F5,E2F6,EDNRB,ANKRD46,HIPK3,YAF2,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,STX2,EPS8,DNAJC27,TAOK3,CORO2B,MED12L,POLK,SUCO,HPCAL4,NELFCD,USP16,MSANTD4,ZMYND11,ARPP21,IGSF5,GGTA1P,PPARGC1A,MALT1,COPS8,HPGDS,TNRC6A,GLUL,MAP7D2,CNDP1,GPM6A,GPR12,GPR34,PCLO,ATP2B1-AS1,GRIA1,GRM5,TMEM25,HPS5,ACOT7,HMGB1,ZDHHC15,FAAP20,MSL1,JAK1,OLFM3,KCNMA1,KCNN2,SYTL4,HECTD2,NCOA7,PIK3AP1,ZNF667-AS1,MARK1,SYT9,MDM4,SRSF12,PPM1L,POC1B,CCDC80,ADAM22,MYCN,MYO9A,NELL2,NEUROD1,NF1,NRCAM,NTRK3,NUMA1,OCRL,OGG1,OPHN1,ETFRF1,PCDH9,PDCD2,PDE4D,BEST3,PFKP,ZDHHC8,PLCL1,JAKMIP1,ZNF426,PRIMPOL,TRHDE,PSAT1,PRRX1,SPATA6,DRAM2,PPP3CB,RASGEF1B,PRKACB,PKN2,GRAMD1C,MASP1,SNRK,CNTLN,PTHLH,PXK,TMEM260,PTPN13,ACSM5,ZSCAN2,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,RET,GTDC1,RFX3,RIC8B,PBRM1,RNASEL,ZFHX4,RNH1,ZNF532,CARF,PCMTD2,RPE,TMEM100,UEVLD,MCMBP,LGR4,RPS20,AMER2,SALL1,SCN2A,CPEB3,SHC4,MAGI3,CHD9,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,SEPHS1,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ZC3H13,ZBTB43,LMO3,ATP10B,CLASP2,SAMSN1,RGL1,STXBP1,KLHL7,FGD4,DNAJC9,PLCB1,CAMTA1,UNC5D,TBCEL,TCEA1,CUX2,ZEB1,TRIM2,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,TGFBR3,AKTIP,TIAM1,NACC2,NR2E1,HEY2,TNS1,TP53BP2,TPD52L2,C9orf85,RGMB,PPIL6,TSC1,TMEFF2,VLDLR,LYPD6,LAMP5,SYNC,CADM2,PRDM2,RGMA,PRDM8,PRDM10,TMEM178A,PCDH15,SLC17A6,NELFE,PLSCR4,FAM13C,MARCH8,PAK5,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-501-3p:mirSVR_lowEffct hsa-miR-501-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.94E-114 2.22E-110 3.15E-113 2.90E-112 288 1180 "ASPHD1,NCKAP5,XKR4,FMNL2,ADCY2,RNF157,ADD3,ERMN,NLGN4X,KLHL13,TXNDC16,ALCAM,PCDH10,KCNT1,AMPD2,AMT,DPP10,USP28,PPFIA2,APP,SLC7A14,SEMA4G,ZBTB10,ATP1A2,ATP2A2,ADAM23,TTLL9,BCHE,C5,MYRF,CACNA1B,VSTM2A,MTMR7,DCLK1,DLGAP1,PPT2,CLTC,QKI,MAP4K4,CNN3,BTF3L4,AKAP5,TOGARAM2,SEC31B,SEC24C,LRIG1,ARHGEF10,MICAL2,OSBPL3,SIPA1L1,CHD5,CST3,KIAA0040,ERC2,RIMS2,SEC14L5,NOS1AP,KIAA0408,HDAC9,GAPVD1,LONRF1,KCTD8,PHYHIP,DGKB,TOMM20,GIT2,DCC,SPATA2,CNIH3,SRGAP3,ARNT2,DMD,DYNC1I1,CPEB2,DTNA,ABCC5,EDN1,ATL1,HIPK3,SEMA3D,CELSR3,EGFR,OLIG2,LRRC17,EPHA5,ZNF549,ADGRV1,MRVI1,FAM198B,ZIC4,EFEMP1,TOMM40L,MED12L,FGF13,FGFR1,FLYWCH1,UFM1,TPK1,NSG2,GAD1,ZMYND11,B4GALNT1,JPH4,GALR1,C15orf41,ATP8A2,GCNT2,GGTA1P,TCERG1,RAB30,GPM6A,GPM6B,GPR12,GRIA1,DIDO1,ADAMTS13,SERP2,ATE1,GRM5,FAM19A2,RNFT2,PTGDR2,KLF12,GABARAPL2,USP54,LRRTM3,KCNA1,OLFM3,KCNJ3,KIF2A,KLRC2,LAMA2,ZFYVE27,MARK1,LYPLAL1,MBNL1,LRP1B,MID1,MOBP,COL28A1,N6AMT1,RSPO2,MYO7A,ZNF862,TCEAL5,NEFH,NELL2,NFIA,NFE2L2,ALDH1L2,SMIM11A,TBC1D25,OCRL,P2RY1,PBX1,PCSK5,PENK,PFKFB3,DUSP26,ANLN,ZNF655,XRN1,ST8SIA5,PLP1,MTRF1L,ING3,MED1,PPM1B,RAB39A,DIRAS2,GDPD1,SNRK,CNTLN,MTMR10,TMEM260,PTPRO,FAM120C,ZNF844,TMEM255A,CCDC40,ZNF793,REV3L,RGS3,ARHGEF10L,RIC8B,RPRD1A,CYB561D1,RORB,ELP2,RPE,UEVLD,FBXW7,ADAL,LGR4,PAQR6,KCNIP3,RTN1,AP1AR,SCN2B,SCN3A,LINC00461,ASIC4,SOX6,GALNT10,SUPT20H,ITSN1,SYBU,NLGN1,CLSTN1,FAM81A,PPP4R3A,ZNF430,RAB3GAP1,SLC9A5,SLC20A2,ATF7IP,TET1,SMARCC2,SMARCE1,RIMS1,SNAP25,SNRPN,FAM126B,SON,PDZD2,WDTC1,MYT1L,SOX2,TAB2,ATP10B,TROVE2,SSTR1,NXT2,ELOVL4,CEP68,DIP2A,KANK1,NECAB1,ZC3H4,SYNE2,VPS13A,ANKRD28,ANKRD12,MTCL1,CAMTA1,CAMSAP2,WWC1,ANO4,WDR7,AZIN2,DOCK9,TMEM151B,RALYL,TEK,PMS2CL,C18orf54,AP4E1,TGFBR3,TJP1,ERCC6L2,CSMD1,NPL,DOK6,AMACR,HSPBP1,PRR18,SLC35A4,FLRT1,XPO1,PCDH20,ZIC1,ZNF711,ZNF708,ZNF154,TMEM198,ZFAND5,CADM2,PRDM8,ADAMTS9,TMEM178A,LINC00632,HRASLS,DOCK8,PHTF2,ADAMTSL3,NHSL1,IFT88,ST8SIA2" MicroRNA hsa-miR-337-3p:mirSVR_highEffct hsa-miR-337-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.57E-114 3.69E-110 5.24E-113 4.82E-112 280 1118 "ABHD6,SLITRK1,CDC7,SORCS1,ESYT2,HECW2,AK2,HFM1,LRRC7,ALCAM,ABCD2,PCDH10,FAM135A,CCDC146,ARMC12,PARG,EPB41L5,GPAM,API5,APP,TMEM263,ZBTB10,ATP2B1,N4BP2L1,SEC11C,BCHE,PROM1,SCAPER,WASF1,CACNA1D,DDR1,CACNB4,LURAP1,THSD7A,PTBP2,VXN,SCARB1,CHM,SYNPR,QKI,CNTN1,AKAP6,AKAP5,SLC4A7,ABI3BP,ACBD5,CHD1L,SLC35F1,C2CD2,RBM39,HAPLN1,CRY2,SNCAIP,ATRNL1,PDE4DIP,PLXNA4,CTNND2,PUM1,ZSCAN23,BOC,FGFR1OP2,LIN54,KIAA0586,CNIH3,MFAP3L,HP1BP3,ALKBH8,CHRDL1,ABI1,E2F5,AASDH,SNX29,EDNRA,SEMA3D,FSD1L,KMT5B,GOLGA7,TMEM35A,EML1,RABEPK,NRN1,RPS6KC1,PTK2B,SCML2,DLC1,FER,POLR1B,FGFR3,ANKFY1,PSD2,UFM1,ST6GALNAC3,MSANTD4,DKK3,GABRA1,GALNT15,GAD1,ARPP21,ERAP1,ZNF559,DISC1,ATP8A2,GDF9,MMADHC,GHR,PPARGC1A,GK,GPR75,GNAO1,GOLGB1,GPM6A,PCLO,GRIA4,GRIK2,BVES,LINC01551,PSIP1,GUCY1B1,HLF,MSL1,ZNF181,C5orf24,RBPJ,LRRCC1,JAK2,SLC35G1,KCND1,KIF5C,KLRC2,INSYN2,LIG4,MARK1,MBNL1,LDLRAD3,LRP1B,MEIS2,SRSF12,MEST,MID1,MMP16,ERICH3,ADAM22,MTR,NCAM1,NFE2L2,CNOT4,NPR2,NTRK3,NUCB2,GPR88,ZDHHC22,CNTN3,PCDH9,PCMT1,PDE3B,CDK14,RETREG1,PCDH18,ING3,EPB41L4B,MED1,PPM1B,PRKAB2,RASGEF1B,CEP41,RAB39A,HYDIN,DCHS2,VPS13C,GON4L,MDGA2,PTCH1,SPDL1,OCIAD1,PTPRN2,TTC13,ZNF615,PID1,CEP97,ARID4A,SLC6A15,ZMAT4,MORC4,PBRM1,ZFHX4,TMLHE,CARF,GSTCD,CYB561D1,RORB,ARMH4,BAALC,GLDN,ACER3,ZNF331,AP1AR,HOGA1,SCP2,SFPQ,NLGN4Y,ZFP30,KIF21A,SH3GL2,SH3GL3,CPEB3,NTNG1,HKDC1,FHOD3,SLITRK3,ANKRD6,SLA,SLC1A7,EPN2,DHX30,FAM214B,ARHGEF40,CCDC88A,CXXC4,ZNF667,SORCS3,SMARCE1,SNRPN,KIF21B,SP4,KDM4C,BEX1,CDK19,RBM26,LMO3,POGZ,ZNF302,FGD4,PRRC2C,VPS13A,SYT1,SYT4,TAC1,TACC1,ANKRD12,SYNE1,PCDHB15,FAM189A1,PCDHB9,GPRIN3,TEX15,CRB1,LEFTY2,HHIP,TJP1,HEY2,FAM124A,RIMBP2,TPM1,RUNDC3B,TTTY15,EIF4ENIF1,PITPNB,WIPF1,ZNF781,LGI4,PCDH20,ZNF142,ZNF154,SPIRE1,WNK1,EMSY,FIP1L1,SLC17A6,PDSS2,GOPC,AMN1,DOCK8,HNRNPA3,CASC15,SSPN,FXR1,FRMD6,NETO2,NETO1,CPNE4" MicroRNA hsa-miR-3129:mirSVR_highEffct hsa-miR-3129:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.64E-114 3.73E-110 5.28E-113 4.86E-112 281 1126 "RALGAPA1,KCNH8,KDM5D,ARID1A,ADD3,SORCS1,KIDINS220,SLC44A5,MTUS1,KCTD16,HACE1,OSBPL8,TXNDC16,TAOK1,ALCAM,CEP126,BCAR3,ANK2,CNIH2,UPRT,SPTBN4,CADPS,CAPRIN2,ZBTB10,ASTN1,ATM,NOL4,DPY19L3,NRP2,DST,SYNJ1,FUBP1,IL33,CA8,CACNB2,KALRN,VSTM2A,NFS1,INA,DCLK1,CDO1,CFL2,SRSF11,MS4A7,QKI,MAP4K4,FHL5,ARMC8,COL4A5,SLC25A27,LETMD1,MYRIP,CPS1,FAM171B,RNF14,CSF1,OSBPL3,VAC14-AS1,PHF14,USP6NL,BOC,FGFR1OP2,ARHGAP24,ZNF337,ZEB2,HP1BP3,SNAP91,NTM,G3BP2,WDR20,FAM107B,DLG2,DRD1,DTNA,ECM2,EBF1,EDN1,EDNRB,ATL1,SGK2,SH3GLB1,FAM13A,AASS,ELAVL2,CALCRL,DCTN4,LRRC17,CEP85L,AMZ2,WAC,SH3YL1,EFEMP1,FCGR3A,ZSCAN30,TESK2,GORAB,MED12L,FGF11,SPSB4,PSD2,ZCCHC17,TACC2,POMT1,TMEM107,HVCN1,UFM1,PDLIM5,STAU2,MSANTD4,HHIPL1,OGA,PHYHIPL,DKK3,CHL1,ZMYND11,ZNF559,MYOZ2,TUBGCP4,TUBA8,COPS8,DBF4,TOX3,PCDH11X,ZNF638,GPD2,GPM6A,LPAR4,EML4,GPR37,RAPGEF4,KIF3A,TMEM25,MAEL,ZHX1,HNMT,MSL1,IFI16,USP54,SCIN,LIX1,ZNF678,KCNH2,KCNN2,KIF2A,KIF5A,KTN1,HECTD2,NCOA7,ZNF667-AS1,MBNL1,MDM4,MEIS2,SRSF12,MITF,XRRA1,MOBP,MOG,ERICH3,ADAM22,NRBP2,PABPC1L2A,NAP1L1,NAP1L3,NCAM2,NF1,NOVA1,DNHD1,SLC11A2,PCSK2,PDE3B,PDE4A,PDE4B,PDGFRA,SERPINE2,PLIN1,PMP22,NXPH1,PPP2R2B,PPP2R5E,KANSL1,CEP41,PRKCB,DCHS2,SYTL2,MDGA2,CNTLN,BDNF-AS,PTPRE,C1orf109,PTPRZ1,MARCH1,CEP97,RADX,KHDRBS2,RGS4,PRIMA1,RNASEL,RORB,CCDC102B,ZC3H14,PTGR2,RTKN,CLIP1,LRRTM4,SCN8A,LINC00461,SCP2,ELMOD1,ZFP30,NTNG1,CTXN2,WDR47,RUFY2,SLC8A3,SHANK2,TMEM132D,SLC20A2,CPEB4,SMARCC2,ANKRD36,RIMS1,LMBRD1,SNRPN,USP33,SOX2,SOX5,DOK5,KDM3A,SP2,EMC1,NPAS3,LMO3,TAB2,CLASP2,SS18,FGD4,NUDT10,PLCB1,SYPL1,KAZN,DMXL2,WDR7,USP32P1,AP4E1,MTMR14,SYNPO2,TRPC3,ANO5,SGK3,TUBB1,PITPNB,BCL2L13,VLDLR,CLDND1,XPO1,XRCC4,ZNF711,MICU3,KCNT2,ATP6V0E2,ZNF138,ZNF177,SPIRE1,SMARCAD1,DHX33,TMEM178A,KCNAB1,PDSS2,RGS7BP,UBE3B,KAT6A,SMIM8,CASC15,ADAMTSL3,JMJD1C,FXR1,IFT88,DPF3,GAN,CPNE4,FAM198A" MicroRNA hsa-miR-1246:mirSVR_highEffct hsa-miR-1246:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.82E-114 4.39E-110 6.22E-113 5.73E-112 298 1265 "KCNH8,METAP1D,XKR4,ADAR,CCDC85A,ADD1,ADD2,AXIN2,BRAP,PWWP2A,ESYT2,INTS2,TAOK1,SEMA6A,CEP126,ARHGAP20,FAM135A,BEGAIN,AMPD3,ANK2,APC,ALS2,BCAS1,CDC14B,MIER1,NUMB,RASL11B,DYNLL1,ATP2B1,ZNF583,RNF182,DPY19L3,MYOM1,RGS9,BCL2L2,NRP2,ZNF599,CFLAR,PROM1,DST,ARHGEF7,GYG2,CA12,CALB1,THSD7A,CAMK2G,ISPD,LDB2,CCKBR,ARHGEF1,TMEM257,C1orf52,CDH2,CDO1,DLGAP1,SRSF11,CHN2,LSMEM2,NRXN1,FAM19A5,QKI,NIPBL,FHL5,AKAP7,AKAP6,SLC25A27,COL9A1,RTTN,ZFP28,CSNK1G3,SLITRK5,CFAP61,CTNND1,CCDC144A,PHF19,LIN54,IP6K1,ZEB2,CEP170,MAGI2,TMEM130,POM121,SMG7,CHRDL1,DMD,DNAH9,DYNC1I1,ABI1,DRP2,PDCD6IP,DUSP9,MAMLD1,DYRK1A,EBF1,EDIL3,FAM135B,FSD1L,YAF2,FAM13A,MBNL2,ABI2,GOLGA7,TENM1,KCNMB2,GPHN,SLC43A2,RTN3,F8,CLVS1,WAC,TMEM132C,SCML2,POLR1B,FGF14,IP6K2,ANKFY1,FYB1,PHYHIPL,GABRG2,HBS1L,ZNF234,WASF3,CPLX2,TUBGCP4,ARFIP1,SESN1,MALT1,TXNL4A,GLRB,GLS,LUZP2,FERMT2,GOLGB1,GPR12,PCLO,RAPGEF4,GRIA1,GRIA4,RFFL,GRIK2,ADAMTS8,GRM1,PSIP1,RNFT2,ADAMTS6,FRMD3,MIER3,HLF,ELOVL5,SHISA6,SMAP1,DOCK7,IL6R,IL6ST,ZNF385B,ITGAV,SLC35G1,KCNJ16,KLC1,STXBP5,LAMP2,SYTL4,HECTD2,NCOA7,LSS,MARK1,MATN2,EFHB,MEF2C,MEIS1,MITF,ERICH3,ZNF680,MSR1,CTNNA3,P2RY13,NCAM1,NDUFA5,NF1,NTRK2,LOC100128398,CLDN11,PCDH9,PDYN,GPR85,PIK3C2A,ZNF655,RC3H2,PRRX1,SH3KBP1,GRAMD1C,MASP1,SAMD9,VPS13C,WBP1L,PTCH1,PTPRB,OCIAD1,EML5,ZNF615,QDPR,SLC25A48,PLEKHB2,RAP1GDS1,RDX,ZYG11B,ZMAT4,REV3L,RFX4,SEC61A2,RIC8B,CARF,ROBO1,RPE,WLS,RTN1,FAM192A,CSRNP3,LRFN5,SCN3A,NTNG1,SHC4,FNDC3A,ANKRD6,WDR37,SLA,PREX2,DHX30,SEPHS1,CCDC88A,SLC12A2,SLCO1A2,TET1,ZFP1,SMARCE1,ANKFN1,UNC80,SOX2,KIF21B,SRPK2,CLASP2,ZNF302,NKAIN2,ZSCAN29,KANK1,AJAP1,SYT11,JMJD6,VAMP1,SYN2,ANKRD28,ADGRL3,ANO4,ZEB1,RALYL,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,GPR161,R3HDM1,C5orf64,TPD52,RGMB,METTL3,CADM1,FAM155A,DNAJC12,SLAIN1,MEAF6,TBC1D15,GUSBP1,ZIC3,ZNF17,ZNF19,ZNF24,TRIM9,AGMO,GPR158-AS1,LYPD6,FSTL5,ZNF195,SMARCAD1,KCNAB1,FAM47E,FAM13C,MARCH8,PHTF2,JMJD1C,NLRP3,FRMD6,NETO2,SENP7" MicroRNA hsa-miR-4323:mirSVR_lowEffct hsa-miR-4323:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-113 6.23E-110 8.80E-113 8.10E-112 319 1445 "CPNE2,RALGAPA1,SERPINA3,KCNH8,ACHE,NCKAP5,SYS1,FAM43B,NDRG2,TMEM132B,GALNT16,ADCY6,TMCC3,ADD2,NLGN4X,AP1B1,AMPD3,ANK3,MAP4K3,PPFIA3,AQP4,PPP4R4,SPTBN4,ARHGAP5,ARNTL,MARK4,PCDHGB4,NUMB,CCAR2,N4BP2L1,RIPK1,BCL2L2,NGB,SLC25A14,HIP1R,CBR1,ENTPD6,L3MBTL4,CACNA2D2,ASIC3,CNOT8,TAOK2,EPS15L1,DGCR9,ABCG2,TMEM184B,SRP14-AS1,HOMER3,CNR1,SLC4A8,IFFO1,MFSD4A,ABCG1,CS,RGS6,MICAL2,ECE2,DCAF8,KIAA0513,LONRF1,IST1,DGKB,SPOCK2,IP6K1,DBI,GIT2,DNAL1,ZBTB24,B3GAT3,COPS7A,WDR20,DNM1,USP3,DMTF1,DPP6,DRD1,ACOT8,GNE,ARRDC4,TOM1,DUSP9,AASDH,EDN1,FAM13A,RASA4,EIF4G1,EPB41,EPS8,ERBB2,EFS,PIPOX,DNAJC27,EZH1,ZNF461,TBC1D16,PTK2B,TESK2,FGF1,TMEM164,NOP56,SORBS1,TMEM107,BRSK1,ABLIM2,TVP23A,SDCBP2,GABBR1,GABRB1,ARPP21,ZNF234,ZNF559,DISC1,SULT1C4,GPR162,GFER,TTBK1,PCDH11X,ZNF638,GPD1,GPD2,ATF7,CCDC184,MCHR1,C1QL4,PLCD4,GRM2,PRDM5,GRM5,LINC00839,TMEM25,RABL2A,ATOH8,MAEL,PADI2,GPR45,PTGDR2,HMGCL,OPALIN,CELF5,IRF8,C2orf72,SOWAHA,C5orf24,INPP5B,KCNC1,KCNH2,KCNK1,KCNK2,KIFC3,KLC1,STXBP5,STMN1,NCOA7,ZFYVE27,MAP4,MAP6,MBNL1,LDLRAD3,MDM4,AFF1,MOBP,MOV10,MSI1,BCO1,PTOV1,MYO9A,RTL5,ZNF862,NASP,NCAM1,NEK1,NELL2,NOVA2,NTRK2,OCRL,OPCML,OPHN1,P2RX7,P2RY1,CNTN3,PCDHGC3,PFKFB2,GDAP1L1,CAMKV,PIK3CD,ZNF655,A2ML1,ZFYVE21,EPB41L4B,POLR2F,RASGEF1B,PRKCZ,MAPK9,GDPD1,PSD,DEF8,PSMD13,PIGG,PTN,ACSM5,RIPOR1,CEP97,TMEM255A,CCDC40,PLEKHB2,RAD51D,KHDRBS2,UBR7,ARHGEF10L,MRPS18A,C12orf49,KLHDC8A,ARMC5,CARF,CCDC25,YY1AP1,SPIN3,STK32B,SYNDIG1,MEG3,RTKN,SAFB,ATXN2,SCN2B,ASIC4,SLC30A10,GALNT10,ASRGL1,RASA3,ITSN1,FAM102A,PPM1E,FUZ,ST3GAL3,NUBPL,PAAF1,ZNF365,FAM81A,DHX30,SORCS3,DMRTC1,SMARCD3,RIMS1,MYO16,SON,CLUAP1,KIF1B,NFASC,SMOC1,INKA2,RGL1,PHLDB1,STX1A,SEPT3,SYP,SLC37A2,TAC1,ROBO3,DNMBP,ADGRL3,EHBP1,TCF4,SIN3B,DMXL2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,ARHGEF12,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,GPR161,ARL10,GZF1,TIAM1,ZFP91,FAM124A,BEX4,TNS1,NR2C2,ZNF346,PRMT8,SMUG1,TRO,TRPC1,NUTM2A,FNDC5,RUSC1,BCL2L13,ZBTB14,EML6,MAP3K12,ADAMTS9,HPS4,KCNAB1,WNK2,PARP11,GJC2,CERS6,FAM219B" MicroRNA hsa-miR-125b-2*:mirSVR_highEffct hsa-miR-125b-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-113 7.48E-110 1.06E-112 9.72E-112 279 1113 "KCNH8,CCDC85A,SLC12A5,SORCS1,ERMN,PWWP2A,PTCHD1,NLGN4X,ZNF608,HFM1,C1QTNF3,SPARCL1,ALCAM,FAM135A,AMPD3,CDC42BPA,LRCH2,CCDC146,ALS2,ASPH,RASL11B,RNF182,NOL4,DPY19L3,CFLAR,SYNJ1,SCAPER,SGCE,CA12,CACNA1B,THSD7A,PTBP2,CAST,CBS,KRIT1,USP2,SLC16A4,TMEM257,C1orf52,DGKI,CDC27,CCPG1,CHM,CHN2,MS4A7,RAB28,PPT2,CLTC,NGEF,NIPBL,AKAP7,ARMC8,SLC35F1,CRMP1,SLC32A1,C1QL2,GDA,RGS6,CSNK1G3,ATRNL1,CST3,DZIP3,APPL1,PHF14,NRSN1,USP6NL,EDRF1,BOC,ZEB2,MYEF2,CEP170,KLHL3,SV2B,KBTBD11,CPEB2,E2F6,FAM135B,EDNRA,PHC2,PHF20L1,PLEKHA1,CALCRL,USPL1,EPHA5,KCNMB2,GPHN,SRRM1,VPS26C,ARMCX1,ACSL4,PTK2B,DLC1,GORAB,KIAA1109,FGF1,HPCAL4,CAP2,FOXF2,VTI1B,SGIP1,NELFCD,JKAMP,ZCCHC17,NPTN,ZNF605,DLL3,PNMA2,GABRB1,GABRB3,GAD2,ZNF234,ERAP1,ZNF559,NEU3,ARFIP1,SESN1,COPS8,DBF4,GLYR1,RAB30,GPM6A,GPM6B,CCDC184,EML4,GRID1,PRDM5,PSIP1,HPS5,HMGCR,TLX1,OPALIN,IRF8,ZIC5,RBPJ,DOCK7,USP54,ZNF385B,LRRTM3,ITGAV,SLC35G1,METTL21A,KCND2,KPNA5,STMN1,HECTD2,MAOB,MARK1,MATN2,AFDN,MSR1,MXI1,NCAM1,CCDC13,NTRK2,NUMA1,OCRL,OPHN1,PCDH8,PCDH9,PDE3B,PDE4D,GPR85,PLIN1,PURG,PDZRN4,PSAT1,SCHIP1,SEPT4,EPB41L4B,SLC36A4,MED1,CRLS1,PRPSAP2,VPS13C,MDGA2,QRICH1,PLPPR1,TMEM260,PTPRO,SH3TC2,FAT4,OXR1,ARID4A,RADX,PBRM1,TMLHE,RAVER2,GSTCD,CNTNAP3,SOX8,CLIP1,RTN1,RYR3,FAM192A,ZFP30,ITSN1,ST3GAL3,PPP4R3A,EPN2,SLC6A11,SEPHS1,SLC12A2,EFHD1,SPHKAP,SLC22A4,CPEB4,RIMS1,SNCA,TMCC1,MYO16,TNIK,ZCCHC24,FNBP1,DOK5,KDM3A,SP2,HECW1,MYCBP2,KDM4C,ZC3H13,NPAS3,C11orf87,TAB2,ERBIN,NXT2,SEPT8,ACSBG1,SYNE2,VPS13A,FNDC9,SYN2,ANKRD28,TACC1,TACR1,EXOC7,TCF4,CLASP1,WDR7,FRYL,SIK3,SIRT1,ZFPM2,CRB1,AKTIP,RIMBP2,SEZ6L,SYNPO2,PPIL6,TTC3,CLHC1,TMEFF2,HIRA,CADM1,UCHL1,UGT8,BCL2L13,CCDC14,VLDLR,WIPF1,ZIC1,ZIC3,GPR158-AS1,MKRN3,TCEAL7,ZFAND5,SMARCAD1,SLC30A3,CA10,CADM2,PRDM2,NAV3,SLC17A6,RGS7BP,FAM13C,KAT6A,SMIM8,MSRB3,FRMD6,SLC4A10" MicroRNA hsa-miR-629:mirSVR_lowEffct hsa-miR-629:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-113 8.04E-110 1.13E-112 1.04E-111 329 1534 "TTYH1,CLK4,ABHD6,C3orf14,CSMD2,KLRC4,SLITRK1,AXIN2,FZD9,BEND6,INTS2,RTL9,OSBPL1A,CC2D2A,FAM135A,KCNT1,MRTFA,ANK3,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,EPB41L5,UPRT,GPAM,ALS2,VAT1L,APP,LGR5,AQP4,CDK10,PPP4R4,NUMB,CCAR2,ATP1B3,ATP2A2,RNF182,ADGRB1,ADGRB3,BBS2,BCHE,NRP2,BTK,CASTOR3,SGCE,GPC2,WASF1,CFAP410,CA8,CACNA1B,CAMK2D,SYT6,KRIT1,CERS5,CCNH,SEPT7,KCNAB3,LGI1,DLGAP1,TBRG4,RCBTB2,MS4A7,NMT2,QKI,SULT4A1,MAP4K4,NIPBL,CNGA3,SLC4A7,SLC35F1,CREM,ENTPD4,SH2B1,CS,MICAL2,IPCEF1,SLITRK5,GPSM1,ARHGAP32,ZFYVE16,TBC1D5,KIAA0586,BRINP1,AIF1L,ARMCX4,ELMSAN1,DCT,C8orf34,HEPH,FBXL5,SNAP91,SV2B,SV2A,DMD,CDON,DMTF1,ABI1,DYRK1A,FAM135B,ATL1,ELAVL4,ELN,STARD3NL,EMX2,OLIG2,EPHB1,RABEPK,EPS8,IGSF6,TLR7,MRVI1,TAOK3,CHST15,FKTN,STRADA,KIAA1109,FGFR1,AMOTL2,SUCO,FLT1,SGIP1,SLC37A3,NOP56,FLYWCH1,NELFCD,EFCAB2,SPECC1,FAM49B,ARFGAP2,CSPG5,HHIPL1,PHYHIPL,STAG2,CHL1,GABRG1,ERAP1,DISC1,ATP8A2,PCDH17,TTBK1,TCERG1,GLS,KCNMB4,GNAS,ZNF782,GPD1,RFFL,LINC01551,FAM107A,ADAMTS6,ATOH8,HAS2,ZHX1,NCKAP1L,LINC01102,ELOVL5,DHX35,IGF1,DISP2,CDH20,KCNJ5,KCNJ10,IPO5,KTN1,LIMS1,SMAD1,MARK1,MAT2A,TM6SF1,KITLG,POC1B,MMP16,ADAM22,MYO9A,PABPC1L2A,NDUFA5,NEUROD1,NF1,VWA2,NPR2,NUMA1,OCRL,OPA1,OPHN1,GLIPR1L2,CNTN3,PCMT1,GNG2,PENK,NLGN3,XRN1,SLC25A23,HMGCLL1,PURG,LRP12,EXOSC10,PRRX1,NECAB2,SPATA6,SH3KBP1,PPP2R2B,RAB39A,EPDR1,CNNM2,SIDT1,GON4L,SNRK,MDGA2,PLPPR1,MTMR10,PTPRG,ZNF615,OXR1,ARID4A,KHDRBS2,BSDC1,MSANTD2,RDX,RFX3,TTLL7,RNF220,PBRM1,ZFHX4,TMLHE,RAVER2,CARF,ROBO1,TMEM206,YY1AP1,TMEM100,LRRK2,HUNK,WLS,RTKN,RTN1,TMEM156,FAM192A,SAFB,SEMA6D,ATXN1,LRFN5,SCN4B,LRRTM4,SCN8A,SGK1,KIF16B,NTNG1,SHC4,CHD9,FBXO11,DZIP1,PAAF1,CCDC88A,SLC12A2,ATF7IP,SMARCA4,DMRTC1,LIMCH1,SNRPN,MYO16,WDTC1,SOX1,TRERF1,ZSWIM8,KIF1B,CDK19,CLSTN2,EPB41L3,ERBIN,NEK4,DIP2A,ACSBG1,KLHL7,ZC3H4,VPS13A,ASTN2,CNTN2,KLHL4,KIAA0930,TRIM2,NAT16,OBSL1,SIK3,FAM200B,DNAH7,DICER1-AS1,ZFPM2,CRB1,AKTIP,SLC44A1,TIAM1,TLR4,R3HDM1,CSMD1,SEZ6L,RASD2,NPL,DOK6,RGMB,PDSS1,STXBP4,TRPC1,ANO5,ZKSCAN5,HIRA,AMOT,SLAIN1,VLDLR,GUSBP1,ETNPPL,ZIC3,ZNF45,ZNF189,ZNF195,WNK1,CADM2,SLC38A1,PRDM10,ADAMTS9,PCDH15,LINC00632,FAM47E,WIPF2,SLC17A6,GOPC,FAM13C,RTN4,PAK5,KAT6A,HNRNPA3,FBXO36" MicroRNA hsa-miR-2909:mirSVR_lowEffct hsa-miR-2909:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.50E-113 8.40E-110 1.18E-112 1.09E-111 263 989 "CPNE2,SLC25A25,NDRG2,BRAP,ADRA1D,ZNF608,MTUS1,OSBPL1A,ZNF578,SPARCL1,PCDH10,FGD2,USP28,PPFIA1,ANXA7,APLP1,UPRT,ALS2,BCAS1,AQP6,TMEM108,TTLL9,BBS2,MPDZ,BCL2L2,LINC00906,C5,RAB29,CALB1,CAMK2G,TRIM41,VSTM2A,CAST,CBS,NEURL1,ZBED1,ZMYM4,ARHGAP33,CHM,MS4A7,SYNPR,NDST3,LHX2,IGFBP7-AS1,COG1,STOML1,CLTA,ARMC8,CREM,RBM39,CLIP3,SNCAIP,MICAL2,SUSD5,ATRNL1,PDE4DIP,CNTNAP2,KIAA0040,APPL1,PLCXD3,ARHGAP32,LONRF1,DCC,PITPNC1,ZNF804A,ZC3H11A,DDX46,DMD,CDON,DPH1,DTNA,ECM2,ABCC9,HIPK3,KLHL5,PHF20L1,APH1A,ABI2,GOLGA7,EIF4G2,PAN3,EMX2,VPS13B,EPB41,KCNMB2,CDHR1,TOMM40L,FDFT1,FECH,FER,MED12L,FGF12,AMOTL2,SUCO,SYNCRIP,AGAP3,SLC37A3,NOP56,C2orf88,TMEM107,UFM1,PDLIM5,ATP2C1,STAU2,HHIPL1,ABLIM2,OGA,ZMAT1,HRASLS5,CHL1,GALNT15,ARPP21,NCKAP1,CSDC2,GHR,PCDH11X,INSM2,GNAO1,GPT2,ATF7,GPR22,CECR2,AP4S1,SLC2A6,HAS2,ELOVL5,MSL1,IDH3B,ZIC5,JAK2,KCNJ3,KCNK1,KCNK2,KIF5C,INSYN2,LIFR,HECTD2,NCOA7,PACRG,KCTD6,XRRA1,MOBP,ZNF680,NAP1L2,SFR1,NEUROD1,SLCO1C1,NTRK2,OGG1,PAK3,PCDH8,PCSK5,CAMKV,ZNF655,CCSER2,KCTD15,FAM216A,PLCD1,SLC25A23,MTRF1L,PMP2,STRN3,PSAT1,ING3,SH3KBP1,RANBP3L,RAB39A,OCIAD1,PTPRE,PTPRZ1,MARCH1,USP47,RADX,KHDRBS2,TTLL7,SEC61A2,PBRM1,DCUN1D2,ALG9,CARF,PCMTD2,SPIN3,LRRK2,KCNIP3,ZNF331,AP1AR,PRCD,SOX6,SFPQ,COPZ1,FERMT1,DOCK10,NTNG1,FBXO11,CTXN2,WDR37,SLC14A1,SLC15A2,ZKSCAN3,SMARCC2,RCOR3,SOX5,SP4,ZC3H13,BEX1,SPTAN1,CDK19,LMO3,CLASP2,CLSTN2,SAMSN1,ZC4H2,FGD4,VPS13A,SYN1,SYN2,TAC1,TACR1,SATB2,TRIM2,CLASP1,PHF24,USP32P1,PCDHA5,FAM200B,ZFPM2,AKTIP,FBXL16,GALNT17,TIAM1,ERCC6L2,TMPO,TPD52L2,RASD2,TPM1,NPL,TRIO,STXBP4,TRPC1,TMEFF2,EIF4ENIF1,LINC00689,UGT8,SLAIN1,BCL2L13,VSNL1,RICTOR,GUSBP1,SF1,ZIC3,TCEAL7,SPIRE1,WNK1,EMSY,PRDM2,NAV3,SLC17A6,FAM13C,DOCK8,UBE3B,SLC39A12,KLHDC1,ST8SIA2" MicroRNA hsa-miR-374a:PITA hsa-miR-374a:PITA_TOP PITA 1.73E-113 9.69E-110 1.36E-112 1.25E-111 234 778 "ABAT,ABR,ACLY,ACTN1,CSMD2,SLITRK1,ADD3,SLC12A5,GRAMD1B,OSBPL8,ARHGAP20,FAM135A,MRTFA,LRCH2,MAP4K3,APC,GAS7,ARHGAP5,ASCL1,ZBTB10,NCOA1,NUMB,TMEM108,ATP1A1,ATP2B2,ARHGEF7,LDLRAD4,CACNB2,REPS2,NOG,NUMBL,CHM,CNOT8,JAM2,KMT2C,HECTD1,NIPBL,AKAP7,AKAP6,SLC25A27,CREB5,HAPLN1,PHACTR3,ST18,FAM131B,BOC,TOX,ZFYVE16,DNAJC6,ZEB2,MFAP3L,RUSC2,DLG2,DLG3,RAB39B,DMD,RCAN1,MAMLD1,DYRK1A,ABCC5,EDIL3,FAM135B,SEMA3D,YAF2,MBNL2,EIF4G1,EIF4G2,TENM1,EN2,EPB41L2,SEZ6,EYA1,MRVI1,NRN1,CLVS1,ACSL4,ZIC4,ATP8A1,MED12L,KIAA1109,FGF13,UBE2E3,MEX3B,FOXG1,PDLIM5,GABRG2,NCKAP1,GBX2,MSTN,AHDC1,PCDH17,PPARGC1A,GK,TCERG1,SPIN1,TNRC6A,GPD2,GPM6A,STON1,STMN2,NR3C1,FAM19A2,FRMD3,KLF12,BACH2,MIER3,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,C5orf24,ZIC5,RBPJ,BRINP3,SLC6A17,KCNA1,KCNC2,KTN1,INSYN2,MAP2,MBNL1,MDM4,LRP1B,MEIS1,AFF1,NEUROD1,NFE2L2,NFIX,NKX2-2,NOVA1,NPTX2,KSR2,OCRL,PDE4B,PDE4D,PDPK1,PIK3C2A,ANLN,ZNF655,RC3H2,MINDY2,PPP2R2C,PRKAB2,GDPD1,SNRK,RAB5B,RALGDS,OXR1,BSDC1,RGS4,PRIMA1,ARHGEF10L,TTLL7,SETD5,ALG9,RORB,HUNK,SATB1,ATXN1,SCN2A,SCN2B,FNIP1,SLC30A10,PEAR1,PPP1R9A,CPEB3,NLGN1,SLC8A1,CPEB4,LMBRD1,MYO16,PDZD2,MYT1L,ZCCHC24,SOX11,SP4,ZNF423,CDK19,RBM26,SRPK2,POGZ,PRRC2C,SYP,SYT1,ANKRD28,TACC1,ANKRD12,CAMSAP2,FBXW11,ANO4,ATMIN,ACSL6,VWC2,TCF4,TRIM2,TCF12,WASHC4,SYNE1,PSD3,PUM2,TJP1,RIMBP2,CSMD1,TNS1,RBFOX2,SEZ6L,ZNF384,TMEFF2,UBE2H,UBE3A,WIPF1,SF1,ZIC3,ZNF711,FMN2,ZBTB38,SMARCAD1,PMEPA1,CADM2,RNF103,PPP1R3F,RGS7BP,GOPC,PAK5,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,JMJD1C,FRMD6,SOCS4,ST8SIA2,SLC4A10" MicroRNA hsa-miR-374b:PITA hsa-miR-374b:PITA_TOP PITA 1.73E-113 9.69E-110 1.36E-112 1.25E-111 234 778 "ABAT,ABR,ACLY,ACTN1,CSMD2,SLITRK1,ADD3,SLC12A5,GRAMD1B,OSBPL8,ARHGAP20,FAM135A,MRTFA,LRCH2,MAP4K3,APC,GAS7,ARHGAP5,ASCL1,ZBTB10,NCOA1,NUMB,TMEM108,ATP1A1,ATP2B2,ARHGEF7,LDLRAD4,CACNB2,REPS2,NOG,NUMBL,CHM,CNOT8,JAM2,KMT2C,HECTD1,NIPBL,AKAP7,AKAP6,SLC25A27,CREB5,HAPLN1,PHACTR3,ST18,FAM131B,BOC,TOX,ZFYVE16,DNAJC6,ZEB2,MFAP3L,RUSC2,DLG2,DLG3,RAB39B,DMD,RCAN1,MAMLD1,DYRK1A,ABCC5,EDIL3,FAM135B,SEMA3D,YAF2,MBNL2,EIF4G1,EIF4G2,TENM1,EN2,EPB41L2,SEZ6,EYA1,MRVI1,NRN1,CLVS1,ACSL4,ZIC4,ATP8A1,MED12L,KIAA1109,FGF13,UBE2E3,MEX3B,FOXG1,PDLIM5,GABRG2,NCKAP1,GBX2,MSTN,AHDC1,PCDH17,PPARGC1A,GK,TCERG1,SPIN1,TNRC6A,GPD2,GPM6A,STON1,STMN2,NR3C1,FAM19A2,FRMD3,KLF12,BACH2,MIER3,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,C5orf24,ZIC5,RBPJ,BRINP3,SLC6A17,KCNA1,KCNC2,KTN1,INSYN2,MAP2,MBNL1,MDM4,LRP1B,MEIS1,AFF1,NEUROD1,NFE2L2,NFIX,NKX2-2,NOVA1,NPTX2,KSR2,OCRL,PDE4B,PDE4D,PDPK1,PIK3C2A,ANLN,ZNF655,RC3H2,MINDY2,PPP2R2C,PRKAB2,GDPD1,SNRK,RAB5B,RALGDS,OXR1,BSDC1,RGS4,PRIMA1,ARHGEF10L,TTLL7,SETD5,ALG9,RORB,HUNK,SATB1,ATXN1,SCN2A,SCN2B,FNIP1,SLC30A10,PEAR1,PPP1R9A,CPEB3,NLGN1,SLC8A1,CPEB4,LMBRD1,MYO16,PDZD2,MYT1L,ZCCHC24,SOX11,SP4,ZNF423,CDK19,RBM26,SRPK2,POGZ,PRRC2C,SYP,SYT1,ANKRD28,TACC1,ANKRD12,CAMSAP2,FBXW11,ANO4,ATMIN,ACSL6,VWC2,TCF4,TRIM2,TCF12,WASHC4,SYNE1,PSD3,PUM2,TJP1,RIMBP2,CSMD1,TNS1,RBFOX2,SEZ6L,ZNF384,TMEFF2,UBE2H,UBE3A,WIPF1,SF1,ZIC3,ZNF711,FMN2,ZBTB38,SMARCAD1,PMEPA1,CADM2,RNF103,PPP1R3F,RGS7BP,GOPC,PAK5,KAT6A,HNRNPA3,PHTF2,ADAMTSL3,JMJD1C,FRMD6,SOCS4,ST8SIA2,SLC4A10" MicroRNA hsa-miR-330-3p:PITA hsa-miR-330-3p:PITA_TOP PITA 1.77E-113 9.96E-110 1.39E-112 1.28E-111 223 703 "ABR,ASIC2,KLHL32,ADD3,SORCS1,ARHGAP20,GPRASP2,AMPH,OGT,DPP10,APBB2,APC,GPAM,API5,USP37,AQP4,TMEM263,CADPS,ZBTB10,RASL11B,ATP2B1,ATP2B2,MTMR9,CADM3,FUBP1,LDLRAD4,BTRC,CALM1,PTBP2,CAMK2G,TRIM41,CBFA2T2,C1orf52,DCLK1,CCPG1,FOXN3,JAM2,NRXN3,COL4A5,ABI3BP,ACBD5,GDA,ARHGEF10,OSBPL3,CSNK1G3,KIAA0408,GAPVD1,TOX,MAML1,IST1,IP6K1,PITPNC1,YTHDC1,ELMO1,SMG7,SPOCK3,FAM107B,DLG2,DLX1,CDON,DPYSL2,DRP2,DYRK1A,ST8SIA3,EDN1,PHC2,EFNA3,RBM12,EFNB3,APH1A,MBNL2,TENM1,ELAVL2,TMEM35A,EPB41L1,EPB41L2,GPHN,ANKRD13B,ERBB4,ETV1,EFEMP1,PPP1R1B,SUCO,HPCAL4,FOXG1,AGAP2,AFF2,DCTN2,ST6GALNAC3,GAB1,PCDH17,TCERG1,KDM2B,GNAO1,PRRC2B,GPM6A,TDRKH,GPR37,GRB10,GRID1,GRM5,CIT,RNF165,SOX21,GUCY1A2,ADAMTS6,CELF3,WIF1,MIER3,HNRNPK,HSF2,KCNA1,KIF2A,ARHGAP12,PACRG,MARK1,MAT2A,MBNL1,CHIC1,LRP1B,MEF2C,MN1,BLOC1S2,MYH3,ZC3H12B,PCDH9,PCMT1,PDE3B,PDE1B,PIK3R1,KCTD15,PMP22,LRP12,PRRX1,PPP2R5C,KANSL1,VSTM2L,PRKAB2,CEP41,MAPK10,PTK2,OCIAD1,PTPRD,PTPRO,FAM120C,NKAIN1,USP47,ARID4A,GTDC1,RIC8B,ZFHX4,RAVER2,KCNIP2,CCDC112,SALL1,SCN2A,SCN2B,SCN3A,FAM19A1,SCP2,GALNT10,TRA2B,PPP1R9A,SH3GL2,PPM1E,KIF16B,SHC4,CHD9,FNDC3A,SLC12A2,RCOR3,IGSF9B,PDZRN3,ZCCHC24,SOX11,SP4,KDM4C,ZNF423,SRPK2,SSTR1,EPB41L3,LARP4,ERBIN,STAU1,SULF2,GSE1,SYNE2,ARHGEF9,PLCB1,SYT5,UNC5D,FBXW11,TBL1X,TCF4,TRIM2,WASHC4,PSD3,PUM2,DICER1,SIRT1,ZMAT3,TGFBR3,GZF1,TJP1,DDHD1,TNS1,TPM3,TRPS1,AMOT,SLAIN1,NSD2,ZBTB14,ZIC3,REEP1,CADM2,LRP8,PRDM8,ITM2C,SLC17A6,RGS7BP,FZD3,SLC4A10,JPH3" MicroRNA hsa-miR-1182:mirSVR_lowEffct hsa-miR-1182:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.28E-113 1.28E-109 1.79E-112 1.65E-111 333 1572 "VWA5B2,ASPHD1,SYN3,SYS1,GALNT13,RNF157,SLC12A5,PWWP2A,PTCHD1,KIDINS220,AP2A2,MTUS1,SNX32,PCDH19,PLA2G6,ADGRF5,SPARCL1,PCDH10,AMPD3,CNIH2,PPFIA1,PKP4,PARG,APAF1,ALS2,BCAS1,SFMBT2,ARHGDIA,ARRB2,MARK4,SLC2A11,ADGRB2,RGS11,BCL2L2,NRP2,CFLAR,SYNJ2,CASTOR3,WASF1,MMD2,CACNA1E,CALM1,HAP1,CANX,CAPN3,SYT6,VSTM2A,BRSK2,SPAG9,KYAT1,LDB2,METTL6,USP6,USP2,SYNGR3,CDK11B,ARHGEF2,SEPT7,SRSF11,CNOT8,NDST3,CLCN4,IGLON5,SMARCAL1,RNF14,ANKRD44,GDA,CSF1,FEZ1,CNTNAP2,CTNND2,DCAF4,ECE2,NOS1AP,GPRASP1,GAPVD1,TCAF1,RIPOR2,TBC1D5,PHYHIP,IST1,GIT2,ELMSAN1,ZEB2,PLEKHM1,MFAP3L,RUSC2,POM121,SV2A,SRGAP3,AK5,CCDC3,HS3ST4,HS3ST2,DTNA,ABCC9,GOLT1B,FAM135B,SGK2,GOLGA7,SORBS3,CERCAM,EPB41L2,COQ7,DMTN,MRPL37,VPS26C,HSPA12B,ABCA8,NSRP1,PTK2B,POLR1B,FGF11,SPSB4,PRKAG2,IP6K2,AGAP3,WDR83,SPECC1,FAM49B,USP21,CGREF1,B3GAT1,NRG3,GABRB3,B4GALNT1,ARPP21,DISC1,ALDH1L1,LYVE1,DBF4,GLYR1,PCDH11X,PSRC1,GPD1,CCDC184,GPR17,MCHR1,TMEM121B,GRK4,RAPGEF4,DIDO1,CIT,COQ10A,ZBTB49,BVES,MFSD2A,LINC01551,AP4S1,ADAMTS6,TMEM179,CELF3,UBE2QL1,PADI2,NXPH2,SYNPO,SHISA6,HTR2A,FAAP20,ATCAY,NKD1,ZIC5,SCIN,JAK2,KCNH1,KCNJ10,KCNJ11,KCNJ16,KIF2A,LINC00634,IPO5,CYP27C1,KTN1,SFXN5,ZFYVE27,MAP4,LDLRAD3,MEF2C,MOBP,PTOV1,MYO6,MYO7A,CCDC13,NF1,NOS1,SETD4,TBC1D25,ODF2,ZDHHC22,PAH,DPY19L2P2,PDE1C,PDE4D,PDPK1,PFKFB3,GDAP1L1,CCSER2,TMEM38A,PLCB2,SDK2,EPB41L4B,PILRA,PPARA,MINDY2,PPP3CB,KANSL1,PRKAB2,RASGEF1B,MAPK4,MAPK10,GRAMD1C,HYDIN,BCAS3,VPS13C,SIDT1,UHRF1BP1,TMEM260,OCIAD1,PTPRE,PYGM,TMEM231,FAM66C,SLC25A41,CRTAC1,RFX5,ZDHHC4,RGS12,SEC61A2,RIC8B,LGI2,ALG9,CARF,CYB561D1,ROBO2,RPE,SNX22,EPHA10,MAP6D1,CCDC112,S100B,FOXRED2,MAPK12,SCN3A,SCP2,ASIC4,ITSN1,DOCK10,CTXN2,PAAF1,SLC1A3,RPH3A,EPN2,SMTN,FAM214B,SLCO1A2,INAVA,UNC80,KDM4B,PDZD2,MYT1L,KIF21B,NMNAT2,LHFPL4,KDM4C,ERC1,PEG10,ZC3H13,SST,SSPO,ZSCAN29,STAC2,NSFL1C,FGD4,RHBDL3,TMEM150C,SYN2,SYP,ANKRD28,TACC1,CAMTA1,CAMSAP2,TBX15,ATMIN,ZFP90,TCF12,NAT16,SLC19A3,OBSL1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TF,CRB1,SPX,ERCC6L2,TNFRSF1B,NPL,TPM2,C9orf85,METTL3,SMUG1,STXBP4,SGK3,UBTF,SLAIN1,ZIC1,KCNT2,ZNF74,TMEM237,POLR3H,TMEM198,DNALI1,LRP8,SLC38A1,PRDM10,LMAN2L,RNF103,SEMA3B,PCDH15,GAL3ST3,SLC17A6,PDSS2,UBE3B,CASC15,RNF170,ADAMTS10,SLC4A10" MicroRNA hsa-miR-3122:mirSVR_lowEffct hsa-miR-3122:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.97E-113 1.67E-109 2.33E-112 2.14E-111 313 1398 "CLK4,TMEM132B,ADCY2,BRAP,PWWP2A,PTCHD1,ADRA1D,OSBPL1A,AK2,ZNF578,C1QTNF1,LRRC7,SEMA6A,SYT13,LRFN1,ANK3,CCDC146,APLP1,DGKD,VAT1L,AMER3,TNRC6C,USP37,SHTN1,STK33,ASPH,NUMB,ASTN1,ATP2B1,SLC2A11,B3GALT2,CADM3,DPY19L3,BACH1,ADGRB2,BCL2L2,CFLAR,ARHGEF7,LINC00906,CACNA1E,CACNB4,CALB1,CBR1,KRIT1,CERS5,AP4M1,CDH2,LRRFIP1,LGI1,NOG,CHN2,STOML1,RAB26,BTF3L4,COL9A3,NECTIN3,SEC31B,CLOCK,PREPL,CREM,CRMP1,CLIP3,SNCAIP,VAC14-AS1,PLXNA4,SDC3,CTH,KIAA0408,ARHGAP32,TOX,AIF1L,ELMSAN1,MYEF2,ELMO1,GSDME,GRIN3A,DMD,SLC12A6,DTNA,ABCC9,AASDH,EDN1,FAM135B,CNNM1,TNK2,EMX2,EPHB1,CEP85L,RTN3,EFEMP1,DLC1,CHST15,FKTN,TESK2,GTF2IRD2,KIAA1109,FGF13,POLK,SUCO,CAP2,SORBS1,PDLIM5,FAM49B,RASL10A,ABLIM2,PHYHIPL,GABRA5,GAD2,BRPF3,ZMYND11,NCKAP1,IQGAP2,GAP43,C15orf41,GCK,GCNT2,CYP46A1,MMADHC,MALT1,ZNF276,GLI2,MSL3,GPT2,PRUNE2,GPM6A,ATF7,FUT10,GRID1,GRIK2,KIF3A,BVES,AP4S1,FAM107A,GUCY1B1,ATOH8,ARHGAP36,AGBL5,SHISA6,EID2B,IRF8,MYLK2,ZNF678,KCNC1,KCNJ3,KCNJ9,KCNK2,KCNK3,CREG2,A1BG-AS1,TTYH2,SFXN5,PAXBP1,ASPRV1,MAPT,MATN3,MBP,TM6SF1,MEIS1,MEIS2,KITLG,AFF1,MN1,WDR49,ZNF92,MYH6,NCAM1,NDUFA5,NEFH,NFYA,NHLH1,VWA2,SMIM11A,NUCB1,IGSF11,OCRL,OLR1,ZDHHC22,SNTG1,PCSK2,PDE4A,PDGFRA,ENPP2,PDYN,FAM98B,GPSM2,FTO,HMGCLL1,MTRF1L,PURG,PNMA3,TRHDE,MAPKAP1,LRP12,PSAT1,SPATA6,SLC36A4,MED1,PTPA,NKAIN4,PRKACB,DCHS2,VPS13C,PTN,OCIAD1,C1orf109,TUG1,ATG16L1,SUSD4,NWD1,OXR1,ARID4A,HKR1,BSDC1,RDX,GTDC1,RFX3,RFX4,RGS3,EXD2,TMEM206,RPE,FBXW7,SPIN3,GLDN,PRR5L,ADAL,NCBP3,ZNF331,SEMA6D,ATXN2,SCP2,SEC14L1,TRIM46,KIF21A,KIF16B,CHD9,CCDC92,ST3GAL3,SLA,KDM4D,YPEL4,SLC15A2,SORCS3,SMARCD3,SMARCE1,MAPKBP1,ZSWIM8,TSPYL2,CLASP2,NKAIN2,SSPO,STAU1,SEPT8,ADHFE1,NSFL1C,VAMP1,PLCB1,COBL,TAC3,TAL1,KLHL4,ZFP90,TCF7L2,ZEB1,AZIN2,NAT16,NSD1,PUM2,ARHGAP9,FRYL,RNF175,CYB561A3,DICER1,CRB1,TIAM1,ERCC6L2,CSMD1,CDK20,PRMT8,STXBP4,TRPS1,ZMYND8,TSC1,SSBP2,GORASP1,DNAJC12,PLEKHH2,CCDC14,XRCC4,SF1,ZNF74,NDRG4,ZNF138,FTSJ1,MAP3K12,XKR7,TMEM178A,SCG2,PCDH15,PCBP4,SLC17A6,RGS7BP,DOCK8,UBE3B,HNRNPA3,FBXO36,CASC15,NUP214,KLHDC1,FRMD6,NETO1,DPF3,CBLN2" MicroRNA hsa-miR-4327:mirSVR_lowEffct hsa-miR-4327:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.80E-113 2.14E-109 2.98E-112 2.74E-111 289 1198 "SERPINA3,ABAT,FMNL2,ADARB2,ADD2,PLEKHH1,USP31,RNF150,BEND6,NLGN4X,GPR158,KIAA1324,TXNDC16,PCDH10,LCORL,MAP4K3,LGR5,MIER1,KIAA1614,ASPH,NUMB,ALDH4A1,SLC4A4,NAE1,CACNA1G,IL33,KALRN,HAP1,MTMR7,P2RX6,SYNGR3,SEPT7,ZBED1,LGI1,LOC730101,NUMBL,STOML1,NIPBL,MAGED1,ACBD5,MROH8,VCAN,SOCS5,VAC14-AS1,FAM169A,SLITRK5,KIAA0040,CTNND1,RIMS2,ECE2,NOS1AP,MYADM,ARHGAP24,MATR3,DGKB,DCC,SPATA2,DCTN1,C8orf34,ZEB2,ELMO1,CEP170,ZC3H11A,EXOG,DMD,TRAPPC9,DPYSL2,DTNB,DYRK1A,EDN1,FAM135B,EDNRA,EDNRB,HIPK3,HEYL,RASGRP1,TMTC1,PHF20L1,KMT5B,ABI2,AASS,KCTD3,SORBS3,EML1,PAN3,USPL1,OLIG2,VPS13B,EPB41L1,KCNMB2,DENND4A,NCALD,DNAJC27,RCSD1,GMPR2,WAC,TBC1D16,ZIC4,DLC1,CHST15,FER,FHL1,UBE2E3,MEX3B,RGPD5,SGIP1,NOP56,ZNF605,STAU2,MSANTD4,GAD1,BRPF3,GALC,SALL3,DISC1,INPP5K,TUBGCP4,SULT1C4,TCERG1,COPS8,TOX3,PCDH11X,HTATSF1,DCLK2,PSRC1,ADGRA3,NUDT21,RAPGEF4,ATP2B1-AS1,GRIA2,GRIK2,PRDM5,GRM7,LINC01089,FAM19A2,RNF165,AP4S1,ATOH8,PADI2,ARHGAP19,TNFAIP8L3,HMGB1,SMAP1,FAM95B1,RBPJ,IL12A,INPP5B,KCNA4,KCNB1,KCNH1,KHK,CREG2,AQP11,CHIC1,MDM4,SCAMP5,POC1B,MMP16,CPNE9,JAKMIP3,ADAM22,CTNNA3,MDGA1,NAP1L3,NCAM2,NEFM,NELL2,NFYA,CLEC9A,SMIM11A,NUMA1,IGSF11,OGG1,ZNF827,PCDH9,PIRT,PDGFRA,PFKFB3,NALCN,GPSM2,NLE1,PCDH18,PDZRN4,RC3H2,POU6F1,PPP2R2C,KANSL1,PRKAB2,CNNM2,ELOVL2,PTPRE,PTPRZ1,CEP97,ZNF793,RASGRF2,KHDRBS2,GTDC1,RGS12,SLC25A36,KLHDC8A,ARMC5,RAVER2,RPE65,FBXW7,KCNIP3,RYR3,ATXN7,HOGA1,ASIC4,ELMOD1,NLGN4Y,KIF21A,PPP1R9A,CPEB3,NTNG1,ST3GAL3,ANKRD6,WDR47,SLC6A1,SLC12A2,SLC14A1,TMEM132D,ELMO2,SMARCE1,FAM126B,UNC80,DOP1A,BDP1,TSNAXIP1,HECW1,ZNF423,CLSTN2,STOX1,SSTR1,ZC4H2,MAPK8IP3,FAM168A,FGD4,VAMP1,NUDT10,SLC37A2,POPDC3,ANO4,SATB2,TRIM2,RPGRIP1L,TCF12,AZIN2,FAM189A1,PMS2CL,ZFPM2,SLC44A1,ERCC6L2,HEY2,TNFRSF1B,PRRT1,TNR,RGMB,PRMT8,FNDC5,TTTY15,TUB,ZKSCAN5,HEPACAM,SLAIN1,BEST1,P2RY12,SF1,ZIC1,ZIC2,KCNT2,ZNF225,EMSY,SLC38A1,RGMA,RNF103,ADAMTS9,MVB12B,PARP11,RGS7BP,FZD3,FBXO36,JMJD1C,ZNF248,RNF170,ZDHHC20,PIANP,SPATA13,SENP7" MicroRNA hsa-miR-150*:mirSVR_lowEffct hsa-miR-150*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.25E-113 2.39E-109 3.33E-112 3.06E-111 318 1443 "SDE2,ASPHD1,ACADM,SYS1,KDM5D,CSMD2,GPRIN1,NDRG3,KLHL32,TMCC3,SORCS1,PLEKHH1,BEND6,SORCS2,C1QTNF3,LRRC7,LTBP4,ALK,SYT13,DPP10,ANK2,USP28,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,DGKZ,GPAM,API5,CPNE5,SPTBN4,ARHGAP5,ARNTL,CDK13,TMEM108,STX16,RNF182,RIPK1,SNAI3-AS1,LINC00847,DST,MTMR2,MMD2,BTRC,CA12,CACNA1B,CACNG1,KALRN,NGB,SPAG9,CBS,LDB2,CD81,REPS2,COPB2,ADGRG1,SOCS6,MS4A7,NDST3,NIPBL,IGLON5,AKAP6,RTTN,ACBD5,CNRIP1,MFSD4A,CDC42BPB,PREPL,AKAP12,HINFP,ANKRD44,GDA,RGS6,OSBPL3,PLCH2,SOCS5,RASGEF1C,PLCXD3,PUM1,CCDC144A,CYBB,ARHGAP32,ZFYVE16,EARS2,IST1,TMEM170A,DCC,KIAA0319,MAGI2,POM121,SNAP91,SV2A,WDR20,KBTBD11,CD99L2,NR1D2,DNM2,DPH1,SLC25A18,DTNA,ECM2,E2F5,SNX29,EDNRA,MBNL2,RASA4,KCTD3,EIF5,IRAK4,PAN3,DCTN4,EPB41,DMTN,EPHB1,ETV1,ANKMY1,RASL12,REEP2,CEP78,KAT8,FGFR1,AMOTL2,RGPD5,FOXO3,COQ5,EFCAB2,UFM1,FAM49B,MPP6,HBS1L,AHCYL1,ZNF234,NCKAP1,GAP43,MTHFD2,DISC1,WASF3,PPARGC1A,MALT1,PCDH11X,STARD3,HTATSF1,ZNF782,PRUNE2,LILRA1,NUDT21,TMEM121B,PCLO,RAPGEF4,GRIA4,ADAMTS13,NR3C1,GRM7,CIT,CLASRP,RNF165,LINC01551,RNFT2,ARHGAP19,HNF4G,ICA1,MSL1,IDH3B,IGF1,JAK1,SLC35G1,KCNA1,KCNMA1,CAMK2N2,MAN2A2,MAP2,MAT2A,MBNL1,KITLG,MOBP,GIT1,COL28A1,BCO1,MDGA1,MYCN,LYRM9,MYO6,MYO7A,NAP1L3,NBL1,NEFM,NF1,CNOT4,DNHD1,NUMA1,SETD4,ODF2,CHAMP1,OGG1,OPCML,PAH,SNTG1,PDE3B,PDE4A,CCSER2,PKD1,PCDH18,PLTP,ANKRD16,PMP2,PMP22,LRP12,SCHIP1,SEPT4,PPARA,MINDY2,CCDC144B,PTPA,KANSL1,VSTM2L,PRKACB,GON4L,PIGG,PTN,TMEM260,PTPRB,PTPRD,PTPRE,C1orf109,PTX3,STRC,RAB5B,RAD51D,RAP1GAP,RASGRF1,FEZF2,RDX,TRIM68,RGR,ZFHX4,ZNF532,RPL15,ARMH4,BAALC,GLDN,MEG3,KCNIP2,RTN1,NCBP3,FAM192A,RMI1,DRAXIN,SLC30A10,SUPT20H,TRA2B,DOCK10,AMBRA1,ST6GAL1,SYBU,RPH3A,SLC2A5,SMTN,SLC8A3,SLC12A2,SLC20A2,SPHKAP,IFT122,PALLD,PDZRN3,KDM4B,USP33,KDM3A,KDM4C,TEX2,IQSEC2,SPART,C11orf87,STX1A,SULF2,PRRC2C,VAMP1,TAC1,ANO4,SIN3B,DMXL2,TCF7,ZEB1,TRIM2,PHF24,HIF3A,TGFBR3,SLC44A1,TMEM9,ACTR6,LRRC8A,TNFRSF1B,TPM1,ZNF346,TRIO,STXBP4,ZMYND8,ANO5,TMEFF2,HIRA,FLRT2,LAT2,DHX33,WNK1,SLC30A4,EMSY,EVI5,PARP6,STOX2,PCDH15,NAV2,WIPF2,PDSS2,ST7,UBE3B,FBXO36,FAM219B,MSRB3,CBLN2,ST8SIA2,GAN" MicroRNA hsa-miR-302f:mirSVR_lowEffct hsa-miR-302f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.76E-113 2.68E-109 3.72E-112 3.43E-111 341 1648 "ACADM,ABHD6,NCKAP5,CSMD3,CCDC85A,ERMN,PLEKHH1,USP31,KIAA1211,ESYT2,SLC24A4,OSBPL8,TXNDC16,CC2D2A,UNC79,TRMT9B,DPP10,TMEM263,ZFYVE28,CDK13,PDE8B,STK33,BRINP2,N4BP2L1,DPY19L3,ATP6V0A1,BACH1,BBS2,BCL7A,BMPR1B,FUBP1,MTMR2,SGCE,CACNA1G,CACNA1E,KALRN,CAMK2G,VXN,VSTM2A,CH25H,ISPD,MAP7,MTMR7,CDC27,CDC42,CDH10,LGI1,CFL2,FOXN3,CHM,NDST3,IGFBP7-AS1,CLCN4,NMT2,CLTA,ABCG2,QKI,NIPBL,FAM149A,SUMF2,COL11A2,AKAP5,ABI3BP,RCHY1,BAG4,HS3ST5,CPS1,GDA,CS,MICAL2,SOCS5,PLCXD3,ST18,CCDC144A,DOCK4,LONRF1,RIMS3,PITPNC1,JAKMIP2,MYEF2,HP1BP3,COPS7A,RHOBTB1,SNAP91,SACS,SPOCK3,NTM,FAM107B,DLG2,DMD,CD99L2,CDON,DRP2,DTNA,MAMLD1,DNAJB6,DYRK1A,AASDH,EDIL3,EDN1,FAM135B,PHC2,HIPK3,RASGRP1,FSD1L,SH3GLB1,SUGP2,MBNL2,KMT5B,EGR3,RASA4,KCTD3,CALCRL,EPB41,KCNMB2,SLC43A2,ETV1,ADGRV1,EYA1,F3,ABCA8,SH3YL1,ZIC4,RACK1,ST3GAL6,TESK2,PRKAG2,POLK,IP6K2,C2orf88,SORBS1,FAM49B,TRIM16,ATP6V1H,DACH2,NRG3,TVP23A,PHYHIPL,MEGF10,GAA,GAB1,ZNF274,IQGAP2,WASF3,TUBGCP4,SESN1,PPARGC1A,GK,COPS8,GLI2,PCDH11X,ZNF638,GPD2,NUDT21,GPR37,PCLO,GRIK2,GRM5,GRM8,KIF3A,GUCY1A1,GUCY1B1,GYG1,WIF1,IRAK3,ZHX1,NEGR1,ZNF546,RBPJ,SCRT2,BRINP3,INPP5B,ZNF385B,KLHL23,KCNJ16,KIT,LMO2,NAT8L,LRP1B,PPM1L,MITF,SAMD5,STK32C,CTNNA3,NCAM1,NFIA,NODAL,NOVA1,NRDC,NUCB2,LOC100128398,CNTN3,PAX6,PBX1,PCSK1,CDK18,PDYN,GPR85,GNG2,ZNF655,XRN1,PLP1,PCDH18,HMGCLL1,PLXNB3,PMP2,SCHIP1,ING3,SLC36A4,RANBP3L,PRKACB,PRKCG,SIDT1,GON4L,SNRK,PSMD13,PTHLH,ELOVL2,PTK2,PTPRB,PTPRN,RIPOR1,RAB5B,RAD52,RAP1GDS1,ENOX1,ZMAT4,RFX3,RERGL,DCUN1D2,ROBO1,EPHA10,FBXW7,ATP8B4,ACER3,LRRK2,CSRNP3,ATXN7,HOGA1,PRCD,CASC3,GALNT10,STUM,SUPT20H,ITSN1,NTNG1,MAGI3,CHD9,FBXO11,ST6GAL1,SYBU,PPP4R3A,RUFY2,KANSL3,SLC6A8,SLC8A1,SLC8A3,SLC12A2,TMEM132D,MYH15,MBD5,FAIM2,DOP1A,SON,SOX1,ZNF423,ZC3H13,RBM26,C11orf87,SRPK2,TAB2,ZNF621,EPB41L3,SS18,NXT2,MAPK8IP3,ZSCAN29,DIP2A,PRRC2C,PLCB1,CAMTA1,FAM208A,MGRN1,TBX15,ACSL6,TRIM2,RPGRIP1L,TCF12,DOCK9,PHF24,RALYL,SLC19A3,PCDHB3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZMAT3,THBS4,ARL10,ASXL3,KAT6B,TPM1,NR2C2,SYNPO2,PDSS1,TRO,STXBP4,TRPS1,TSN,CADM1,FAM155A,SLC35A4,DNAJC12,WRN,CFAP298,ZIC3,POLR3H,ZNF189,FTSJ1,LAMP5,PLPPR5,ZFAND5,SLC38A1,RNF103,SLC17A7,TRIM16L,DOCK8,RTN4,TRAM2-AS1,SLC39A12,NETO1,ST8SIA2,SLC4A10,GAN" MicroRNA hsa-miR-452*:mirSVR_highEffct hsa-miR-452*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.29E-113 2.97E-109 4.13E-112 3.80E-111 306 1341 "DGCR6,KCNH8,ACADM,CLK4,ADCY6,BEND6,INTS2,WDR35,ALCAM,CEP126,SYT13,AMPH,OGT,ANK2,USP28,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,DGKD,ALS2,BCAS1,USP37,APP,TMEM263,RGS20,ASPH,ZBTB10,NCOA1,RASL11B,TMEM108,DPY19L3,ADAM23,TTLL9,BARD1,GPR146,CFLAR,SYNJ2,ARHGEF7,NAE1,LINC00906,SCAPER,JAZF1,OSGIN2,CACNB2,LURAP1,CALM1,CAMK2B,CAST,RUNX1T1,CBR1,LDB2,INA,CBFA2T2,SCARB1,TMEM257,ZBED1,ZMYM4,SOCS6,CHM,CHN1,ZBED5,NRXN3,CLTC,NIPBL,ARMC8,COL4A5,COL9A1,BAG4,CLOCK,NCOR1,SEC24C,ARHGEF10,ATRNL1,VAC14-AS1,RIMS2,CYBB,DOCK4,IST1,YTHDC1,C2CD2L,DDX46,PLPPR4,SPOCK3,EXOG,RAB39B,DMD,DPH1,CASP8AP2,DRD1,PDCD6IP,ECM2,EDNRA,FCF1,KLHL5,SUGP2,RASA4,DCTN4,EMX2,RASGRP2,GPHN,DENND4A,PIPOX,SIRPB1,EYA1,FABP7,CEP78,PRKAG2,SUCO,CAP2,FLT1,SLC37A3,NELFCD,CINP,NPTN,CGREF1,STAU2,ABLIM2,ZMAT1,HRASLS5,GABRA3,AHCYL1,GFRA2,DHRS4,GLRB,STARD3,ZNF638,GNAS,GPM6B,GPR12,B4GALNT4,GPR34,RAPGEF1,PLPP7,MAP4K5,GYG1,IRAK3,NXPH2,GPR45,AGBL5,HSP90AA1,MYLK2,C5orf24,IGFBP1,ZIC5,IL6ST,ITGAV,KCND1,KCNJ3,STXBP5,PAXBP1,ARHGAP12,NCOA7,SMAD9,C1orf194,ZFYVE27,MAT2A,MDM4,LRP1B,MIA2,MID1,POC1B,AFDN,MOBP,MRPL42,PABPC1L2A,NCAM1,NEFH,NF1,SLCO1C1,PCBP3,NUCB2,NUMA1,OPRL1,CLDN11,SNTG1,PAK3,PAX6,PCDH9,PCMT1,PDE4B,PDE4D,BEST3,PIK3CD,ZNF655,A2ML1,SNX10,FAM216A,PLCL1,ANKRD16,LRP12,SEPT4,PPM1B,HYDIN,PROX1,PSMD13,ANKHD1,PTHLH,TMEM260,ZSCAN32,PTPRD,SLC25A48,ACSS3,RAD52,ZNF793,FAT4,SUSD4,RADX,VEPH1,ZYG11B,ZDHHC4,SEC61A2,RIC8B,PBRM1,ZFHX4,CCDC82,SUGCT,ELP2,CCDC102B,MRAP2,EPHA10,FBXW7,ATP8B4,LRRK2,SYNDIG1,MEG3,SOX8,TMEM156,ATXN7,SCN8A,PRCD,FERMT1,DOCK10,FUZ,CHD9,FBXO11,NLGN1,SEC31A,SLC1A6,LRRC55,SLC6A11,SEPHS1,RAB3GAP1,SLC11A1,ATF7IP,MBD5,UNC80,RBM34,SP2,SP4,LMO3,TAB2,NKAIN2,KANK1,STXBP1,PRRC2C,NUDT10,DNAJC9,ASTN2,DDHD2,TAF9,DNMBP,ANO4,CUX2,ZEB1,HIF3A,SIK3,AP4E1,HHIP,HEY1,DDHD1,TLR4,NR2E1,BEX4,C5orf64,RGMB,SYNPO2,TRIO,AMACR,ANKRD20A2,TMEFF2,OSBP2,MGAT5B,VLDLR,P2RY12,CLDND1,SLC13A3,PCDH20,ZNF23,TRIM9,FSTL5,ZSCAN26,PLPPR5,SMARCAD1,SYNC,SLC30A4,EMSY,LRP8,SCG2,PCDH15,GAL3ST3,WNK3,PDSS2,FZD3,MRPL47,RTN4,FRMD6" MicroRNA hsa-miR-4310:mirSVR_highEffct hsa-miR-4310:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.22E-113 4.06E-109 5.63E-112 5.18E-111 305 1334 "ABCF1,FMNL2,GALNT13,ADD2,ERMN,PLEKHH1,PWWP2A,KIAA1211,DPY19L2P4,MTUS1,KLHL13,KCTD16,LRRC7,ALAD,SPOP,ARHGAP20,GPRASP2,OGT,CDC42BPA,CNIH2,GPAM,ALS2,BCAS1,SHTN1,TMEM263,ZFYVE28,MARCH3,ASPH,EIF4G3,ATP2B1,ZNF582,N4BP2L1,DOCK11,DCAF5,NRP2,BLM,ZNF599,MTMR2,C5,CACNA2D1,THSD7A,VSTM2A,PRC1,CD86,ZBED1,CDC42,COPB2,SRSF11,CASC2,RAB33A,CLCN3,BTF3L4,ABI3BP,AHCTF1,CREM,HAPLN1,CRYM,SNCAIP,OSBPL3,VCAN,DZIP3,APPL1,PPP6R2,RUBCN,DOCK4,ZFYVE16,CENPL,IST1,DGKB,YTHDC1,JAKMIP2,CEP170,DDX46,POM121,G3BP2,WDR20,KIF19,DLX1,DMD,DMTF1,ABI1,ECM2,FAM78B,DNAJB6,DYRK1A,E2F6,EBF1,TSPAN5,FAM135B,ATL1,FRY,RBM12,PHF20L1,MBNL2,PLEKHA1,TUBD1,COQ7,RCAN2,LRRC17,EPHA5,CEP85L,F5,ZNF461,WAC,ACSL4,GORAB,OLFM1,FGF11,FGF13,PRKAG2,VTI1B,ATP13A4,FLT1,DCTN2,SMC2,CELF1,NSG1,STAU2,ABLIM2,SDCBP2,MEGF11,GABRG2,CAB39,AHCYL1,GALC,GALR1,CPLX2,PPARGC1A,GLI2,TOX3,OS9,GNAO1,ADGRA3,GPD2,GPM6A,ATP2B1-AS1,GRIA2,GRIA4,NR3C1,GRM1,PRDM5,GRM8,ZBTB49,ZHX1,NXPH2,NCKAP1L,INSYN1,HNRNPK,RBPJ,DOCK7,LIX1,SLC6A17,ITGAM,C2CD4C,SLC35G1,KCNH2,KCNJ11,IPO5,STXBP5,LMO2,NCOA7,MAP4,AQP11,MATN2,MBD1,LRP1B,MEF2C,MEIS2,KITLG,AFDN,NDUFA5,IDNK,NF1,OTOGL,NOVA1,DNHD1,CNTN3,PRTG,PDE4D,SLC10A4,GPR85,PIK3R1,XRN1,PLP1,SMIM7,LRP12,SCHIP1,EPB41L4B,DRAM2,PPM1B,TATDN3,PRKAB2,PRKACB,PKIA,EPDR1,MAPK9,GRAMD1C,PRPH,MASP1,GDPD2,TMEM260,PTPN13,PTPRO,FAM120C,PTX3,TTC13,PPP2R3C,CEP97,ZNF793,FAT4,ZNF493,RASGRF2,KHDRBS2,BSDC1,ZYG11B,RET,REV3L,RFX4,SLC25A36,DCUN1D2,SETD5,CARF,RPE,FBXW7,MCMBP,ATP8B4,PRR5L,SYNDIG1,ZNF568,SALL1,SCN2A,LRRTM4,SCN8A,FNIP1,ZFP2,TRA2B,KIF21A,SH3GL3,PPM1E,MAGI3,CNKSR2,NLGN1,ANKRD6,PAAF1,CCDC88A,SLC20A2,GKAP1,RCOR3,MBD5,LMBRD1,SNRPN,UNC80,SON,SOX1,MYT1L,GLT8D1,RBM26,NPAS3,LMO3,CLASP2,TROVE2,LRRC4,NEK4,ADHFE1,SYT11,COBL,C12orf76,KAZN,PJA1,CAMTA1,CAMSAP2,ADGRL3,EHBP1,VWC2,SATB2,TCF7L2,TRIM2,RPGRIP1L,ZFPM2,SLC44A1,TJP1,CSMD1,TPM3,RGMB,PRMT8,RUNDC3B,SGK3,RPL7L1,XRCC4,ZNF19,ZNF45,EML6,FTSJ1,WNK1,CADM2,NT5M,PRDM10,HPS4,CIAPIN1,PARP11,FZD3,NHSL1,FXR1,NETO1,SLC4A10" MicroRNA hsa-miR-32-5p:TargetScan hsa-miR-32-5p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-25-3p:TargetScan hsa-miR-25-3p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-92b-3p:TargetScan hsa-miR-92b-3p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-92a-3p:TargetScan hsa-miR-92a-3p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-363-3p:TargetScan hsa-miR-363-3p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-367-3p:TargetScan hsa-miR-367-3p TargetScan 7.97E-113 4.48E-109 6.16E-112 5.67E-111 233 776 "NCKAP5,CSMD3,ELFN2,DSCAML1,RNF157,GRAMD1B,PWWP2A,KIAA1211,RNF150,GPR158,HECW2,CASKIN1,MARCH4,PCDH10,FAM135A,PITPNM2,CDC42BPA,DPP10,ANK3,CASK,MARCH3,ASPH,NCOA1,ASTN1,DDX3Y,INSYN2B,ATP2A2,MTMR9,B3GALT2,ADAM23,BACH1,HCN2,BMP7,CDK5R1,FUBP1,CACNA1I,BSN,LDLRAD4,CACNA2D1,DIRAS1,KALRN,CAMK2A,RUNX1T1,AIFM1,CDC27,CDC42,DLGAP2,CLGN,CFL2,FOXN3,CHGA,RAB3C,KIAA1549L,COG1,QKI,NIPBL,SEC31B,ENTPD4,HAPLN1,ANKRD44,AATK,ARHGEF10,SDC3,ERC2,APPL1,RIMS2,DOCK4,DCAF8,RASSF2,LIN54,GIT2,DBT,DCC,PITPNC1,PLEKHM1,KLHL3,G3BP2,RABGAP1L,CALN1,CPEB2,PDCD6IP,ARRDC4,HIPK3,FRY,ABI2,GOLGA7,EIF4G2,PLEKHA1,RGS17,PCOLCE2,EIF1,EN2,EPS8,DNAJC27,CEND1,KIAA1109,POLK,FOXG1,NPTN,NSG1,DKK3,GAA,GABRA3,AHCYL1,IQGAP2,GAP43,MTHFD2,CPLX2,CPLX1,GLYR1,GLUL,PCDH11X,DCLK2,PRRC2B,GPM6A,GRIA1,GRIK3,GRM2,GRM7,KAT7,HAS2,MIER3,SCRG1,NEGR1,C5orf24,RBPJ,ITGAV,C2CD4C,KCNA1,KCND2,KCNH1,KCNJ3,KCNK3,KCNN3,KPNA5,IPO5,INSYN2,PAXBP1,LMO2,PIK3AP1,MARK1,LRP1B,MITF,AFF1,MMP16,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NOVA2,CLDN11,GPR137C,KCNK10,PDE3B,GPR173,NOMO2,CCSER2,PURG,PRKAB2,CEP41,PRKAR1B,MAPK8,PROX1,DCHS2,PTPRD,PTPRG,PLEKHB2,RAD51D,BSDC1,REV3L,RFX3,RGS3,KLHL11,ROBO1,ROBO2,RPL15,FBXW7,RYR3,AP1AR,CSRNP3,ATXN1,ATXN7,FAM19A1,SCN8A,FNIP1,PPP1R9A,CPEB3,MYO18A,CHD9,FAM81A,CPEB4,CXXC4,PALLD,FAM126B,PDZD2,MYT1L,DOK5,HECW1,MYCBP2,KIF1B,NPAS3,C11orf87,LRRC4,ELOVL4,RGL1,ATP11A,DDHD2,ANO4,ATMIN,SATB2,DOCK9,FRYL,HHIP,NACC2,CSMD1,RBFOX2,PCDH20,FMN2,PMEPA1,CADM2,EVI5,ADAMTS9,NAV3,MARCH8,PHTF2,ADAMTSL3,MSRB3,FXR1,NETO1,GAN" MicroRNA hsa-miR-34b:mirSVR_highEffct hsa-miR-34b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-113 4.85E-109 6.66E-112 6.13E-111 291 1218 "SDE2,ABCF1,KCNH8,CLK4,ABHD6,NCKAP5,CSMD3,NDRG3,PWWP2A,ADRB2,NLGN4X,MTUS1,GPR158,ABCD2,MARCH4,OGT,LRCH2,PPFIA1,APBA2,ALS2,SHROOM2,CASK,ASPH,BRINP2,DPY19L3,ADGRB3,SEC11C,DST,SCAPER,CALM1,PTBP2,ISPD,SPAG9,CCK,C1orf52,CDC42,LGI1,L3MBTL4,MAGI1,CHM,CHN2,NDST3,QKI,FHL5,SLC4A7,MYRIP,CNRIP1,HS3ST5,HAPLN1,HINFP,GDA,TRIM69,ARHGEF10,VCAN,ARHGAP32,FGFR1OP2,TOX,LIN54,DGKB,ZEB2,KIAA0319,FBXO25,DMD,DNAH9,ACOT8,DTNA,DTNB,DYRK1A,E2F5,FAM135B,EDNRA,EDNRB,FAM13A,PHF20L1,APH1A,MBNL2,TENM1,PLEKHA1,EMX2,RCAN2,DENND4A,IGSF6,EYA1,AMZ2,WAC,ZSCAN30,FGF14,FGFR1,FOXG1,PSD2,COQ5,C2orf88,ZCCHC17,UFM1,FAM49B,NPTN,ATP6V1H,DKK3,GABRA2,GABRB3,TRAF3IP2,GALC,NCKAP1,MTHFD2,CPLX1,MYOZ2,ARFIP1,GDF9,MMADHC,PCDH17,GLRB,PCDH11X,ZNF638,CBX1,INSM2,RAB40B,GPR12,PCLO,CNTRL,GRID1,LINC01551,GYG1,ATG4C,MAEL,UBE2QL1,C1orf94,ZHX1,FRMD3,HNRNPK,MSL1,RBPJ,ZNF678,KCNMA1,CREG2,KIF2A,KIF5A,KLC1,NCOA7,PIK3AP1,MAP2,LYPLAL1,MARK3,MEST,MIA2,AFDN,ADAM22,MSR1,CTNNA3,LYRM9,LAYN,MYO9A,MYT1,NAP1L1,NINJ2,DNHD1,NUCB2,OMG,P2RY1,GPR137C,CNTN3,PDE4D,PDGFRA,GPR85,PIK3CD,ZNF655,CCSER2,PLCL1,LRP12,PSAT1,SCHIP1,PRRX1,EPB41L4B,PPM1B,TATDN3,KANSL1,PRKACB,PKN2,RELN,VPS13C,SLC22A23,MDGA2,WDR25,ANKHD1,SPDL1,TMEM260,PTPRD,PTPRE,ZSCAN2,SLC25A48,BSDC1,SLC6A15,ZYG11B,GTDC1,FIGN,RLBP1,RIC8B,PBRM1,RPRD1A,SETD5,CARF,ROBO2,ELP2,RPE,NEK11,ARMH4,AP1AR,MIR124-2HG,ATXN2,SCP2,ASRGL1,MRAS,SCAF8,NLGN4Y,SCG5,KIF21A,CPEB3,NTNG1,CHD9,FNDC3A,SLITRK3,NLGN1,ANKRD6,ZNF365,SLC1A6,SEPHS1,SLC12A2,ELMO2,BTBD7,ATF7IP,TET1,RCOR3,SNAP25,SNCA,MBD5,SNRPN,PALLD,FAM126B,MYO16,UNC80,SON,SOX1,MYT1L,SOX5,ZNF423,ZC3H13,CDK19,SPART,LMO3,TAB2,PBLD,SS18,NXT2,TTBK2,KLHL7,VPS13A,NUDT10,DDHD2,ADGRL3,EHBP1,USP22,PCDHB4,PCDHB3,PUM2,USP32P1,ARHGAP9,GPRIN3,AHCYL2,ZNF106,AKTIP,ASXL3,HEY2,TMOD1,TP53BP2,DCBLD1,TSN,ANKRD20A2,RPL7L1,FAM181B,RICTOR,SF1,PCDH20,LAMP5,SMARCAD1,PCDH15,CAB39L,PDSS2,KAT6A,PHTF2,CASC15,TIGD6,SNX14" MicroRNA hsa-miR-3074:mirSVR_highEffct hsa-miR-3074:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.68E-113 4.88E-109 6.69E-112 6.16E-111 276 1097 "VWA5B2,RALGAPA1,ACHE,CLK4,ADD3,AXIN2,PLEKHH1,ADORA1,PWWP2A,HACE1,ZFAT,GPAM,CACHD1,ASPH,ATM,SLC4A4,ALDH7A1,NOL4,BARD1,CDK5R1,SYNJ1,ARHGEF7,FUBP1,OSGIN2,KALRN,CANX,CH25H,CBLN1,KRIT1,CCNH,MTMR7,CD38,CDH2,MAGI1,DLGAP1,CFL2,B4GALT6,RAB33A,PLAA,NRXN1,C4orf33,NIPBL,TMEM155,AKAP6,SLC25A27,LETMD1,SLC4A7,ABI3BP,RCHY1,RTTN,AKAP12,ANKRD44,NCOR1,CSF2RA,FEZ2,CST3,APPL1,CTH,CTNND2,ST18,CYBB,HDAC9,GAPVD1,ZNF804A,C8orf34,ZEB2,ALKBH8,RHOBTB1,NTM,G3BP2,DLG2,RAB39B,CASP8AP2,DRD1,ABCC5,EDIL3,EDNRB,ANKRD46,FAM13A,KMT5B,ASB3,PLEKHA1,CALCRL,KCNMB2,DENND4A,TMEM74,ADGRV1,ABCA8,ZIC4,CEP78,GORAB,FER,SUCO,ANKFY1,SLC37A3,SMC2,NPTN,SARAF,AP4B1,ZNF512,ZMAT1,MEGF11,BRPF3,FAM120B,RAPGEF6,ZNF274,PPARGC1A,RAB30,PRUNE2,GPM6A,TDRKH,GPR22,LPAR4,EML4,GRB10,GRIA2,GRIA4,AP4S1,RABL2A,CELF3,WIF1,IRAK3,ZHX1,ARHGAP36,ELOVL5,HNMT,TCEAL6,DHX35,LIX1,LRRTM1,NME9,ITGAV,KCNA2,KCNJ10,KCNN2,KHK,MARK1,LYPLAL1,TM6SF1,MDM4,LRP1B,MID1,MXI1,MYO9A,PABPC1L2A,NAP1L1,NAP1L2,NEK1,NF1,NFE2L2,SLC11A2,ODF2,ZNF713,CNTN3,PCMT1,PRTG,PDE4D,PIK3C2A,ANLN,FAM218A,KCTD15,PLP1,HMGCLL1,PMP2,STRN3,PSAT1,POLR2F,PPP2R5E,PRKACB,PKIA,MAPK9,RELN,SAMD9,VPS13C,SIDT1,PTCH1,ANKHD1,TMEM260,OCIAD1,PTPRE,FAT4,DBX2,RBBP6,SLC6A15,ERI2,TTLL7,RIT2,KLHL11,SEC61A2,RNF220,CARF,ROM1,CCDC102B,SPIN3,LRRK2,CNTNAP3,KCNIP1,TRAPPC13,RMI1,ATXN7,LRFN5,LINC00461,ELMOD1,GALNT10,SUPT20H,PPM1E,CPEB3,CHD9,FHOD3,SEC31A,SLC1A3,PKNOX2,SEPHS1,SLC8A1,NAPB,RIMS1,UNC80,SON,GLT8D1,ZNF423,KIF1B,RBM26,LMO3,ATP10B,CLASP2,NUDT10,PLCB1,SEMA4A,PJA1,TAF9,ACSL6,TRIM2,RPGRIP1L,WDR7,SYNE1,PCDHB6,FRYL,AHCYL2,TEX15,TEK,DICER1,SIRT1,ZFPM2,AP4E1,TIAM1,ASXL3,BHLHB9,TLR4,ERCC6L2,TNS1,NPL,WBP2,DCBLD1,ANO5,EIF4ENIF1,UBE2H,PLEKHH2,MTCH1,MEAF6,WNT7A,CLDND1,XRCC4,ZNF711,GPR158-AS1,ZNF138,PCDH15,NAV2,PLSCR4,HRASLS,PHTF2,ACTR3B,JMJD1C,NETO1,DPF3,ST8SIA2,GAN" MicroRNA hsa-miR-3180-5p:mirSVR_highEffct hsa-miR-3180-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-112 6.23E-109 8.54E-112 7.87E-111 321 1474 "ABAT,ASPHD1,ASIC2,TMEM132B,ADCY2,SLITRK1,SLC12A5,KIDINS220,SLC24A4,ZNF608,HECW2,KLHL13,HACE1,SPOP,ABCD2,ARHGAP20,OGT,SEMA7A,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,CACHD1,PRX,TMEM263,ARRB2,CDK13,NCOA1,BACH1,SEC11C,SYNJ2,SCAPER,CACNB2,THSD7A,KALRN,SYT6,VSTM2A,CAST,RHBDL1,PRC1,MTMR7,SLC16A4,CD86,TMEM257,SEPT7,LRRFIP1,CDR1,CCPG1,SRSF11,CHN2,CASC2,JAM2,RAB28,IGFBP7-AS1,NRXN1,FBXO7,ABCG2,SLC25A27,ABI3BP,HS3ST5,CP,CREM,RBM39,ANKRD44,GDA,CS,RGS6,ATRNL1,PLXNA4,PHF14,CTH,SLC45A1,KIAA0408,DOCK4,TCAF1,DCAF8,KIAA0513,ZFYVE16,TOMM20,DCC,ZEB2,ZBTB24,KIAA0753,CEP170,SACS,CCDC3,DMD,NR1D2,DPP6,PDCD6IP,DTNA,ABCC5,ANKRD46,RASGRP1,FAM13A,PHF20L1,SUGP2,ABI2,CALCRL,EPHB1,RABEPK,STX2,ETV1,TLR7,F5,WAC,CORO2B,RACK1,CEP78,TOMM40L,FDFT1,KIAA1109,FGF11,FGF12,PRKAG2,POLK,NBEA,TMEM107,SMC2,USP16,FAM49B,ATP6V1H,CELF1,ZNF512,OGA,ZMAT1,DKK3,GABRA1,HRASLS5,GABRA5,IP6K3,IQGAP2,DISC1,INPP5K,GCNT2,SESN1,COPS8,DBF4,SPIN1,TNRC6A,GNAS,GPT2,GPM6B,TDRKH,GRIA2,GRM5,AP4S1,GUCY1B1,PADI2,GABARAPL2,HNRNPK,NEGR1,HTR2A,IDH3B,DOCK7,ITPKB,SLC35G1,KCNA2,KCNJ3,KCNJ16,KCNK1,KCNK2,KIF2A,SYTL4,FGFBP3,SMAD1,NAT8L,MAN2A2,MAP4,MEIS2,SRSF12,COL28A1,ADAM22,CTNNA3,MTTP,NAP1L1,NDP,SFR1,NF1,NOVA1,NPTX1,NTRK2,NUCB1,ODF2,OLR1,OMG,OXTR,P2RY1,PBX1,PDE4B,PDE4D,GNG2,CYTL1,PIK3C2A,FAM216A,SEPT4,NXPH1,POU3F2,DRAM2,PPARA,PPP2R5E,PPP3CB,PKIA,RAB39A,DIRAS2,GDPD1,DCHS2,VPS13C,SNRK,MDGA2,PSMD13,PLPPR1,BDNF-AS,PTPRN2,MARCH1,SUSD4,ZCWPW1,ENOX1,SLC6A15,REV3L,PRRT2,RFX4,TTLL7,SEC61A2,RIC8B,ZFHX4,TMLHE,CCDC25,RPE,BAALC,ZC3H14,ACER3,TCP11L1,PAQR6,MEG3,ABCA11P,KCNIP1,RXRA,ZNF331,FAM19A1,SOX6,ASRGL1,MRAS,ZFP30,FERMT1,ST3GAL3,NUBPL,WDR37,ABLIM3,ZNF365,CCDC88A,SLC9A5,SLC12A2,BTBD7,NAXD,SMARCD3,SMARCE1,ANKRD36,CMTR2,SON,KDM3A,SP4,SPP1,C11orf87,SRPK2,EPB41L3,SS18,ERBIN,FGD4,VPS13A,ANKRD28,DDHD2,KLHL4,ANO4,VWA3A,CUX2,RPGRIP1L,WASHC4,WDR7,ARHGEF12,AHCYL2,RNF216P1,FAM200B,PMS2CL,CRB1,ITGB3BP,AP4E1,MTMR14,DDHD1,TLL2,TMPO,FAM124A,WBP2,ANO5,HSPBP1,SLC35A4,UBTF,SLAIN1,VSNL1,ZBTB14,ZNF24,MICU3,ZSCAN26,ZXDA,EMSY,MFF,CSDE1,PRDM8,XKR7,PRDM10,SCG2,NELFE,PAK5,CASC15,RSPRY1,TRAM2-AS1,ZNF248,TTC7A,ZDHHC20,FXR1,SPATA13" MicroRNA hsa-miR-345:mirSVR_lowEffct hsa-miR-345:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-112 6.97E-109 9.53E-112 8.78E-111 338 1626 "ABAT,NCKAP5,SYS1,CSMD2,ADCY6,ADD1,OLMALINC,OSBPL1A,KIAA1324,WDR35,AK2,ALCAM,FAM135A,ZFAT,CNIH2,SUGT1P4-STRA6LP-CCDC180,ALS2,APP,KIAA1614,MADD,TMEM108,CHID1,SLC2A11,ADAM15,BACH1,SNAI3-AS1,BBS2,RGS9,DCAF5,NRP2,CFLAR,DST,CASTOR3,MTMR3,GYG2,GPC2,OSGIN2,LDLRAD4,CACNA1D,CALB1,KALRN,SYT6,ISPD,SPAG9,INA,AIFM1,CBFA2T2,AP4M1,LRRFIP1,MAGI1,UBE2L6,ADGRG1,TAOK2,LSMEM2,C7orf61,ABCG2,CNGA3,AKAP7,COL4A5,BTF3L4,LETMD1,CHD1L,PNKD,HINFP,TRIM69,IPCEF1,PDE4DIP,FAM169A,CTH,NRSN1,RIMS2,DOCK4,ARHGAP32,TBC1D5,PHYHIP,DAPK1,YTHDC1,B3GAT3,TMEM130,RHOBTB1,SPOCK3,G3BP2,FAM107B,ARNT2,ZNF582-AS1,RAB39B,NYAP1,USP3,CPEB2,FAM57B,SLC25A18,FARSB,ABCC5,EDNRA,SEMA3D,PHF20L1,RASA4,AASS,IRAK4,EPHA5,EFS,RCSD1,EXTL2,FAM198B,WAC,PTK2B,STRADA,GTF2IRD2,FGF1,FGF11,TMEM164,CAMSAP1,SUCO,ZCCHC17,SMC2,ARFGAP2,ERGIC3,SARAF,TVP23A,OGA,STAG2,MEGF10,GABRG2,FAM120B,IP6K3,GATM,GCNT2,SRCAP,GPR162,NFU1,GGT7,ZNF276,GLRB,PCDH11X,STARD3,KDM2B,ADGRA3,TDRKH,GPR12,STON1,RAPGEF4,GRIA2,PLCD4,GRID1,GRM8,BTN2A1,ZBTB49,BVES,RNFT2,CELF3,GPR45,LINC01102,ELOVL5,GABARAPL2,IRF8,ZNF546,RBPJ,TJAP1,PLD5,SCIN,IL6ST,LRRTM3,KCNJ5,KCNK2,KCNN1,LAMP2,STMN1,SYTL4,MAN2A2,MARK1,LDLRAD3,PPM1L,MMP16,MTTP,LYRM9,MYO7A,ZNF862,PABPC1L2A,HNRNPM,NF1,ALDH1L2,NKX2-2,DNHD1,SLC11A2,PAH,PAK3,PCSK1,PDE1A,PDE1C,PDE4D,OLA1,NOMO2,A2ML1,CCSER2,GPSM2,PLCL1,EPN1,PMP2,CDIP1,LRP12,SDK2,ING3,FAT3,DRAM2,MED1,PPM1B,PPP5C,PRKCB,PKN2,EPDR1,MAPK9,SAMD9,SYTL2,TMEM104,CNTLN,PTCH1,ZSCAN32,PTPRB,PTPRD,PTPRN,PTPRO,PTPRZ1,RIPOR1,PPP2R3C,QDPR,CEP97,ACSS3,ZNF793,SH3TC2,NWD1,RASGRF2,SLC6A15,ZYG11B,RGS3,RGS7,SLC25A36,ZNF532,TMLHE,EXD2,CARF,ROBO2,RPL15,MCMBP,ATP8B4,ACER3,STK32B,RXRG,CCDC112,TRAPPC13,S100B,PRCD,FNIP1,ASIC4,COPZ1,CPEB3,BCAN,NUBPL,ABLIM3,ZNF365,SLC1A7,FAM214B,SLC8A1,ARHGEF40,SIRT2,SLC12A4,SLCO1A2,ZNF667,OGDHL,ANKRD36,INAVA,USP33,SCN3B,DOP1A,TRERF1,BDP1,DOK5,LHFPL4,C11orf87,TROVE2,COLGALT2,INKA2,ELOVL4,KANK1,SULF2,GSE1,FAM168A,SYT11,FNDC9,C3orf70,PJA1,DDHD2,TAL1,UNC5D,SMG6,ACSL6,TCF4,CUX2,WASHC4,WDR7,NAT16,RALYL,SLC19A3,TNS2,AHCYL2,ENHO,TIAM1,TLL2,BHLHB9,TNFRSF1B,RBFOX2,ELP5,TRO,TRPS1,TMPRSS5,TSC1,TTC3,TUB,CLHC1,NSD2,SLC47A2,ZNF142,POLR3H,MEIS3,UPF3A,SLC30A3,RGMA,PRDM8,ADAMTS9,SLC17A6,KAT6A,FBXO36,CASC15,NUP214,JMJD1C,TIGD6,FRMD6,CBLN2,SLC4A10" MicroRNA hsa-miR-1224-5p:mirSVR_lowEffct hsa-miR-1224-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.43E-112 8.04E-109 1.10E-111 1.01E-110 341 1654 "DPF1,SYS1,CSMD2,ARID1A,NDRG2,KLHL32,ADCY2,CCDC85A,GALNT13,RNF157,ADD2,SORCS1,ADORA1,SORCS2,USP35,GOLGA7B,AMPD2,ANK1,LCORL,CNIH2,SHTN1,AQP4,CADPS,CDK13,CCDC74A,ZBTB10,NUMB,TMEM108,ATP1A2,SLC4A4,STX16,N4BP2L1,RIPK1,LINC00847,BCHE,FGF17,GPR146,MYRF,MMD2,CACNA1B,DDR1,CACNA2D1,KALRN,CAMK2D,HIP1R,PRC1,KYAT1,SCARB1,AP4M1,DCLK1,LGI1,DLGAP1,CCPG1,CHRM1,CASC2,NDST3,EPS15L1,KIAA1549L,NRXN2,NMT2,TJP2,ABCG2,MAP4K4,CNGA3,ARMC8,AKAP6,RCHY1,ZNF385A,FAM171B,PNKD,CRY2,CST3,UBXN2A,PHF14,GREB1,DCAF4,SEC14L5,ECE2,BOC,ZNF337,LONRF1,DAPK1,GIT2,MFAP3L,COPS7A,POM121,SGSM2,DLX1,GRIN3A,RAB39B,SLC29A4,DOCK2,SLC12A6,ACOT8,DRP2,E2F6,EDN1,CNNM1,YAF2,TMEM132E,EIF5,CDHR1,TLR7,CEND1,SCML2,ATP8A1,FCGRT,ZNF589,FER,OLFM1,FGF13,FGFR1,FGR,AMOTL2,POLK,NELFCD,TMEM175,SORBS1,SPECC1,HVCN1,ERGIC3,CGREF1,KBTBD12,TBR1,NRG3,ABLIM2,ZMAT1,STAG2,GAB1,FAM120B,B4GALNT1,ZNF274,MTHFD2,ATP8A2,IGSF5,LYVE1,ZNF276,RAB30,GLUL,PCDH11X,ZNF638,HTATSF1,ADGRA3,GPD1,CECR2,GRIA2,NR3C1,KAT7,LINC01551,FAM222A,FRMD3,BACH2,HNF4G,ZDHHC15,OPALIN,DHX35,LRRC75A,SHISA6,HTR5A,SOWAHA,IGSF1,IL6ST,ZNF678,KCNA1,OLFM3,KCND1,KCNJ9,KCNK2,KCNK3,KHK,LINC00634,A1BG-AS1,IPO5,LAMP2,STMN1,PAXBP1,FGFBP3,ASPRV1,GPR155,MAN2A2,ZFYVE27,MEIS2,STK32C,MSR1,MX1,MYO7A,RTL5,ZNF862,NCAM2,NEK1,NF1,NOS1,NPY,NTRK2,OCRL,LOC100128398,CLDN11,PCDH9,PCSK5,PIRT,SLC10A4,ZNF655,PKD1,FAM216A,SLC25A23,PMP2,ING3,FAT3,NXPH1,FSD1,PPP2R5E,NKAIN4,RAB39A,MAPK4,MASP1,GDPD2,TMEM104,PIGG,CNTLN,PTK2,ZSCAN32,CASTOR1,PEX2,ZSCAN2,TUG1,PPP2R3C,SH3TC2,ATG16L1,OXR1,ZMAT4,TRIM68,REV3L,FIGN,RGS4,RGS12,DCUN1D2,CARF,GSTCD,ROBO1,KIRREL1,ROBO2,RPE65,TCP11L1,STK32B,RYR3,ZNF331,SCN2B,SCN4B,FAM19A1,SCP2,SEC14L1,CASC3,SCAF8,ASAP3,MYO18A,BCAN,ST3GAL3,WDR37,ZNF365,SLC1A3,SLC2A5,EPN2,SMTN,SLC8A3,SIRT2,SLC9A5,SLC11A1,TMEM132D,ELMO2,EFHD1,CPEB4,ARFGAP1,CDK5RAP2,INTS9,MYH15,SNCA,DOK5,ZSWIM8,SPTB,KIF1B,ZBTB43,NFASC,C11orf87,ITPRID2,EPB41L3,NKAIN2,NXT2,MAPK8IP3,KANK1,GSE1,ARHGEF9,PLCB1,ARC,SYT1,SLC37A2,SYT4,TAC3,MTCL1,CAMTA1,TAL1,ANO4,SIN3B,RPGRIP1L,CLASP1,WDR7,USP32P1,TF,CRB1,AP4E1,ZFP91,ERCC6L2,HEY2,TNS1,RASD2,NPL,ZNF346,SYNPO2,TRPS1,FNDC5,SSBP2,HEPACAM,RPRM,FLRT2,ZNF709,CLDND1,XPO1,ZIC3,MICU3,ATP6V0E2,SLC26A10,TMEM237,DPYSL5,INTS3,PRDM2,LRP8,TMEM178A,EPM2A,RNF170,PIANP,PRRT4,JPH3" MicroRNA hsa-miR-4286:mirSVR_lowEffct hsa-miR-4286:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-112 9.97E-109 1.36E-111 1.25E-110 290 1213 "TTYH1,SERPINA3,SYN3,CSMD3,RNF157,ADD2,BRAP,SLC12A5,SORCS1,PTCHD1,RTL9,OSBPL8,ALAD,BEGAIN,OGT,PI16,CCDC146,SUGT1P4-STRA6LP-CCDC180,APBB1,UPRT,DGKD,SHROOM2,SEMA4G,PRX,TMEM263,CCDC74A,ASPH,PCDHGB4,RASL11B,ATP1B3,ATP6V0A1,FUBP1,C1QC,CACNA1I,CDK5R2,CA4,CACNB2,SLC25A14,SPAG9,CBLN1,SCARB1,C1orf52,REPS2,CDC42,KCNAB3,TBRG4,CHN2,CHRM1,CPNE6,RAB33A,IGFBP7-AS1,ZFYVE9,PLAA,PPT2,TJP2,IGLON5,SLC4A8,CP,SLC35F1,ANKRD44,TRIM69,CS,PDE4DIP,RUBCN,CYBB,ZFYVE16,GIT2,SIRPA,COPS7A,DDX46,POM121,SNAP91,PARD6A,SV2A,SRGAP3,G3BP2,WDR20,CHRDL1,CPEB2,DOCK2,DPP6,ACOT8,ABI1,DYRK1A,ABCC9,E2F5,EDN1,SEMA3D,EFNA3,TNK2,C3orf18,OLIG2,RCAN2,CDKL3,EZH1,FCGR1A,TESK2,KIAA1109,FGF1,FOXG1,C1orf61,FLNC,SGIP1,NOP56,ATP2C1,CELF1,DACH2,ABLIM2,FYB1,NEURL4,ZNF274,ERAP1,C15orf41,ATP8A2,GFRA1,GGT5,GLS,GLUL,TDRKH,GRIA4,GRM7,BTN2A1,PTPN5,TOX2,PADI2,BACH2,LRRC75A,SHISA6,NKD1,RBPJ,LIX1,IL6R,RIPPLY2,INPP5B,KCNH1,KCNJ5,KCNJ10,PIK3AP1,LOC100128239,MDFI,CHIC1,LDLRAD3,MDM4,MEIS1,MIA2,SCAMP5,MOBP,MOG,GIT1,DBNL,MTR,MXI1,LYRM9,NBL1,NCAM1,RCOR2,NEK1,NHLH1,NNAT,NTRK2,NTRK3,OLR1,CLDN11,OXTR,ZNF827,TREM2,PCDHGC3,PFKFB2,PFKFB3,GDAP1L1,ZNF655,SNX10,GPSM2,PLCD1,PNMA3,POLR2F,MED1,PPP2R2C,PTPA,PRKAB2,MASP1,BCAS3,GDPD2,CNTLN,MTMR10,PID1,TMEM255A,ROGDI,ZNF493,VEPH1,GAL3ST4,DPF2,RFX3,RNF220,TMLHE,EPHA10,CNTNAP3,MEG3,ST6GALNAC6,KCNIP3,ATXN2,ATXN7,ASIC4,SOX6,CASC3,GALNT10,COPZ1,NLGN4Y,FAM102A,PPM1E,ST6GAL1,SYBU,NLGN1,PAAF1,SLA,SLC1A3,DHX30,SLC6A7,ARHGEF40,SLC12A4,NAPB,SCMH1,ARFGAP1,IFT122,UNC80,USP33,TEX2,NFASC,COLGALT2,NKAIN2,ELOVL4,SEPT8,PHLDB1,SEPT3,FGD4,NUDT10,FNDC9,SLC37A2,TACC1,ROBO3,FAM208A,PDLIM2,AGTPBP1,KLHL4,SIN3B,TPCN2,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,NSD1,USP32P1,C18orf54,FBXL16,BEX4,KCTD2,SYNPO2,METTL3,FNDC5,DCBLD1,AMOT,PLEKHH2,ZNF781,ATP6V0E2,ZNF70,SLC26A10,CRB2,ZBTB16,ZNF154,SPIRE1,LRP8,RGMA,PCDH15,PPP1R3F,ITM2C,PCBP4,SLC17A6,UBE3B,TMEM63C,NUP214" MicroRNA hsa-miR-296-3p:mirSVR_lowEffct hsa-miR-296-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-112 1.18E-108 1.61E-111 1.48E-110 318 1451 "ABCF1,ASPHD1,ABHD6,ARID1A,ADD2,PLEKHH1,KIAA1211,BEND6,MTUS1,SNX32,KLHL13,RTL9,SEMA6A,AMPD3,UPRT,LGR5,AQP6,MIER1,SEMA4G,PRX,ARRB2,CDK13,ASCL1,DACT3,CHID1,ADGRB2,LINC00847,NRP2,KSR1,BMP7,ST3GAL5,ARHGEF7,BTK,MTMR2,JAZF1,BAIAP3,IL33,CA8,CACNA1E,CALB1,CBFA2T2,SEPT7,CDC42,DCLK1,ZMYM4,LARGE1,UBE2L6,PLEKHB1,NRXN3,NRXN2,TPP1,SULT4A1,IGLON5,SLC25A27,BTF3L4,ZNF385A,PNKD,SLC32A1,CRYBB1,GDA,CLIP3,CS,SEC24C,SDC3,APPL1,PHF14,GREB1,RIMS2,EARS2,MATR3,DAPK1,SCRN1,HEPH,COPS7A,GUCD1,POM121,SV2B,SV2A,TMCC2,MTX3,KIF19,SEC16A,DLG2,GRIN3A,HS3ST2,USP3,DMTF1,DPH1,PDCD6IP,TMTC1,EFNB3,KMT5B,GOLGA7,STARD3NL,HSD17B14,OLIG2,EPB41L1,DMTN,EPHA5,MRPL37,MRPL10,DNAJC27,REEP2,CLVS1,ABCA8,WAC,TOMM40L,TESK2,KAT8,ZNF589,GORAB,OLFM1,FGF13,FGR,CAMSAP1,FHL1,EFCAB2,ATP2C1,CGREF1,B3GAT1,OGA,MEGF10,GABBR1,GABRA3,CHL1,CAB39,TMEM8B,SEPT9,LRRC37A6P,KIRREL3,SPIN1,AIFM3,ZNF638,KCNMB4,WDFY3-AS2,PSRC1,ADGRA3,FUT10,ATP2B1-AS1,GRIA1,GRIA2,RFFL,ADAMTS13,ADAMTS6,HAS2,HPS5,PADI2,ZHX1,LINC01102,HMGB1,HMGCL,AGBL5,HSD17B1,ATCAY,MSL1,IDH3B,ZIC5,BRINP3,KIT,STXBP5,PAXBP1,ARHGAP12,ZFYVE27,MAP4,MBNL1,MEIS1,KITLG,GIT1,JAKMIP3,MYO9A,PABPC1L2A,ZC3H12B,SFR1,CCDC13,ALDH1L2,CNOT4,NOVA1,DNHD1,LRIT2,SMIM11A,HCN1,NTRK2,NUMA1,TBC1D25,OGDH,OLR1,OPA1,OPCML,P2RX7,CNTN3,PDE1A,BEST3,NLGN3,PLCB2,ANKRD16,LRP12,RETREG2,MED1,PPM1B,KANSL1,PKN2,GRAMD1C,HYDIN,PRPH,KLK6,SYTL2,DEF8,CNTLN,ELOVL2,STK32A,EML5,PTPRE,TUG1,PPP2R3C,SLC25A48,FAM66C,HKR1,ZDHHC14,PRRT2,RFX3,RGS3,ARHGEF10L,MRPS18A,RNASEL,YY1AP1,KIAA0895L,MAP6D1,ZNF568,DGLUCY,MIR124-2HG,ATXN2,FNIP1,SMPD3,MRAS,ITSN1,FBXO11,BCAN,NLGN1,PAAF1,BTBD3,LRRC55,ATF7IP,NAXD,SNRPN,PDZRN3,SON,KIF21B,SOX15,NMNAT2,ENKUR,TEX2,PEG10,ZNF423,DBNDD2,TSPYL2,CLASP2,CLSTN2,ST5,APOM,SEPT8,ADHFE1,STXBP1,PLCB1,SYN1,SLC37A2,KAZN,KLHL4,ANO4,ZFP90,TCF12,AKNA,ARHGAP9,ZFPM2,THBS4,FBXL16,RELL2,DAAM2,SEZ6L,NPL,TPM2,TPM3,WBP2,RGMB,ZNF346,STXBP4,TRPC1,ZMYND8,PPIL6,DCBLD1,RFTN2,TTC3,ZKSCAN5,CLHC1,MGAT5B,VSNL1,WIPF1,PORCN,RICTOR,ZIC3,CRB2,TCEAL7,AMZ1,EML6,SYNC,UPF3A,MAP3K12,MFF,PRDM2,DNALI1,SLC38A1,STMN4,SEMA3B,GAL3ST3,ITM2C,EPM2A,RGS7BP,UBE3B,NETO2" MicroRNA hsa-miR-1291:mirSVR_lowEffct hsa-miR-1291:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.64E-112 1.48E-108 2.02E-111 1.86E-110 332 1576 "DGCR6,ASIC1,NCKAP5,GALNT16,ADCY6,SLC12A5,GRAMD1B,ADORA2A,PTCHD1,NLGN4X,PCDH19,TBC1D14,ADGRF5,UNC79,MRTFA,DOC2A,AMPD2,AMPH,PI16,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,DGKD,FAM131A,APOC2,API5,USP37,ASGR1,BRINP2,ATP2B3,TTLL9,ADGRB1,ADGRB2,BBS2,BCL2L2,DCAF5,NRP2,KSR1,BTK,KALRN,CAMK2D,BRSK2,RHBDL1,ENTPD6,AP4M1,ARHGEF2,CDC27,LARGE1,GPR37L1,ADGRG1,NGEF,QKI,RAB26,CNGA3,SMARCAL1,PNKD,SH2B1,SNCAIP,FEZ1,SDC3,ARHGEF4,GPSM1,NOS1AP,BOC,CENPL,RASSF2,PHYHIP,ARMCX4,ZEB2,TIAM2,KIAA0753,C2CD2L,POM121,RHOBTB1,SGSM2,TMCC2,CCDC3,KBTBD11,DLG4,DMPK,HS3ST2,SLC29A4,DPH1,DPYSL2,DYRK1A,USH1C,EDN1,SGK2,FRY,SIDT2,RBM12,GPR61,SUGP2,RASA4,KCTD3,TNK2,CERCAM,VPS13B,COQ7,RASGRP2,ANKMY1,TLR7,SIRPB1,MRVI1,ECSIT,F5,REEP2,PTK2B,TOMM40L,ZSCAN30,GTF2IRD2,FGF11,FGFR3,MEX3B,HPCAL4,CAP2,SYNCRIP,AGAP3,SEMA6C,NOP56,FLYWCH1,C2orf88,SORBS1,POMT1,SMC2,ARFGAP2,NSG2,CELF1,CGREF1,GPR153,HHIPL1,TMEM151A,BRSK1,HRASLS5,GALNT15,BRPF3,B4GALNT1,ACSS1,LRRC37A6P,TUBGCP4,TUBA8,GLYR1,GLS,MSL3,PCDH11X,KCNMB4,FERMT2,MCHR1,CECR2,GRIN2C,GRM2,GRM7,GSN,RNF165,ZBTB45,TMEM179,NCKAP1L,HMGCL,CFAP126,DHX35,LRRC75A,IRF8,MYLK2,NKD1,GAREM2,RBPJ,KNDC1,TJAP1,HES5,IL6R,SCRT2,INSM1,KCNJ3,KCNJ5,KCNN3,LINC00634,SYTL4,LSS,MEF2C,MEIS1,MGAT3,XRRA1,MN1,MOBP,MOG,MSR1,PTOV1,NRBP2,MXI1,HNRNPM,FXYD6,NNAT,NOVA2,LRIT2,NPTX2,HCN1,ODF2,OPHN1,OXTR,PAX6,PDE1B,PFKFB4,GDAP1L1,CAMKV,TMIE,ZNF655,XRN1,SLC25A23,RETREG2,PACSIN1,POLR2F,CRLS1,PTPA,NKAIN4,PRKCB,MAPK3,KLK6,PIGG,PLPPR1,UHRF1BP1,PTPRD,PTPRE,PTPRO,ZSCAN2,TUG1,SLC25A48,CCDC40,ROGDI,RASGRF2,RBBP6,HKR1,TRIM68,RGR,RGS12,PRIMA1,ARHGEF10L,SLC25A36,PBRM1,CCDC102B,SNX22,RPL15,KIAA0895L,ATP8B4,ADAL,ST6GALNAC6,ZNF568,MAPK12,ELMOD1,ASRGL1,ITSN1,FERMT1,ASAP3,CPEB3,MAGI3,ST6GAL1,BCAN,CTXN2,ABLIM3,RPH3A,URGCP,RUFY2,SLC6A7,SLC8A1,SLC9A5,SLC11A1,EFHD1,SPHKAP,NAXD,KIF13A,FAIM2,SNRPN,PALLD,MYO16,WDTC1,TSNAXIP1,NMNAT2,SPTB,IQSEC2,TSPYL2,NFASC,TAB2,SSPO,DIP2A,GANAB,SEPT3,ACSBG1,SUPT5H,MLST8,TAL1,UNC5D,FBXW11,SMG6,KLHL4,TCF7L2,TPCN2,SZT2,WDR7,FAM189A1,GPRIN3,AHCYL2,CYB561A3,CRB1,LEFTY2,ARL10,ENHO,RELL2,TNR,CDK20,ZNF346,TRO,TRPM2,TTTY15,HIRA,CLEC2L,KLC2,PORCN,GUSBP1,SLC13A3,ZIC3,CELF4,PRDM2,XKR7,SIGLEC10,WNK2,HNRNPA3,FBXO36,CASC15,FAM219B,VANGL2,ADAMTS10,LAS1L" MicroRNA hsa-miR-519a:PITA hsa-miR-519a:PITA_TOP PITA 3.04E-112 1.71E-108 2.31E-111 2.13E-110 216 665 "USP31,SLC24A4,GPR158,SRPX,CDC42BPA,LRCH2,USP28,API5,SHTN1,STK33,CAPRIN2,RASL11B,DDX3Y,ATP2B1,B3GALT2,NOL4,KIF1A,BCL2L2,BCL7A,NRP2,SYNJ1,MAP7,USP6,NEURL1,REPS2,DLGAP2,CFL2,FOXN3,SOCS6,QKI,BTF3L4,SLC4A7,RCHY1,AHCTF1,PNKD,CREB5,CRY2,GDA,LRIG1,CHD5,NRSN1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,MAGI2,SACS,DLG2,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,EPHA5,ANKRD13B,ERBB4,ETV1,EZH1,F3,ACSL4,TAOK3,TESK2,CAMSAP1,FOXG1,FOXF2,ANKFY1,SGIP1,NBEA,GAB1,RUNDC3A,TOX3,TNRC6A,RAPGEF4,GRB10,ADAMTS8,GRM7,CIT,SOX21,HAS2,HPS5,KLF12,MIER3,TLX1,IGF1,JAK1,KCNA1,KCND2,KCNJ10,KCNN2,KIF5A,CAMK2N2,SFXN5,ARHGAP12,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NEUROD2,NF1,NFIA,NFIX,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,CCSER2,EPB41L4B,FAT3,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,RAB5B,CEP97,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,SCN3A,FAM19A1,HSPA4L,FAM102A,PPP1R9A,KIF16B,CPEB3,CHD9,SLITRK3,SLC1A2,FAM81A,RUFY2,CCDC88A,CPEB4,RIMS1,FAM126B,MYT1L,SOX5,SP4,TEX2,TSPYL2,SMOC1,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,CAMSAP2,UNC5D,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,ZFP91,HEY2,RIMBP2,R3HDM1,TRPC1,UBC,FAM155A,UBE3A,SLAIN1,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,CA10,MAP3K12,EMSY,MFF,CSDE1,WNK3,SLC17A6,RGS7BP,GOPC,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-519b-3p:PITA hsa-miR-519b-3p:PITA_TOP PITA 3.04E-112 1.71E-108 2.31E-111 2.13E-110 216 665 "USP31,SLC24A4,GPR158,SRPX,CDC42BPA,LRCH2,USP28,API5,SHTN1,STK33,CAPRIN2,RASL11B,DDX3Y,ATP2B1,B3GALT2,NOL4,KIF1A,BCL2L2,BCL7A,NRP2,SYNJ1,MAP7,USP6,NEURL1,REPS2,DLGAP2,CFL2,FOXN3,SOCS6,QKI,BTF3L4,SLC4A7,RCHY1,AHCTF1,PNKD,CREB5,CRY2,GDA,LRIG1,CHD5,NRSN1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,MAGI2,SACS,DLG2,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,EPHA5,ANKRD13B,ERBB4,ETV1,EZH1,F3,ACSL4,TAOK3,TESK2,CAMSAP1,FOXG1,FOXF2,ANKFY1,SGIP1,NBEA,GAB1,RUNDC3A,TOX3,TNRC6A,RAPGEF4,GRB10,ADAMTS8,GRM7,CIT,SOX21,HAS2,HPS5,KLF12,MIER3,TLX1,IGF1,JAK1,KCNA1,KCND2,KCNJ10,KCNN2,KIF5A,CAMK2N2,SFXN5,ARHGAP12,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NEUROD2,NF1,NFIA,NFIX,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,CCSER2,EPB41L4B,FAT3,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,RAB5B,CEP97,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,SCN3A,FAM19A1,HSPA4L,FAM102A,PPP1R9A,KIF16B,CPEB3,CHD9,SLITRK3,SLC1A2,FAM81A,RUFY2,CCDC88A,CPEB4,RIMS1,FAM126B,MYT1L,SOX5,SP4,TEX2,TSPYL2,SMOC1,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,CAMSAP2,UNC5D,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,ZFP91,HEY2,RIMBP2,R3HDM1,TRPC1,UBC,FAM155A,UBE3A,SLAIN1,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,CA10,MAP3K12,EMSY,MFF,CSDE1,WNK3,SLC17A6,RGS7BP,GOPC,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-519c-3p:PITA hsa-miR-519c-3p:PITA_TOP PITA 3.04E-112 1.71E-108 2.31E-111 2.13E-110 216 665 "USP31,SLC24A4,GPR158,SRPX,CDC42BPA,LRCH2,USP28,API5,SHTN1,STK33,CAPRIN2,RASL11B,DDX3Y,ATP2B1,B3GALT2,NOL4,KIF1A,BCL2L2,BCL7A,NRP2,SYNJ1,MAP7,USP6,NEURL1,REPS2,DLGAP2,CFL2,FOXN3,SOCS6,QKI,BTF3L4,SLC4A7,RCHY1,AHCTF1,PNKD,CREB5,CRY2,GDA,LRIG1,CHD5,NRSN1,PPP6R2,RUBCN,BOC,ARHGAP24,DCAF8,ZFYVE16,MAML1,FBXL5,MAGI2,SACS,DLG2,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,APH1A,KMT5B,EIF4G2,TENM1,PAN3,EMX2,EPHA5,ANKRD13B,ERBB4,ETV1,EZH1,F3,ACSL4,TAOK3,TESK2,CAMSAP1,FOXG1,FOXF2,ANKFY1,SGIP1,NBEA,GAB1,RUNDC3A,TOX3,TNRC6A,RAPGEF4,GRB10,ADAMTS8,GRM7,CIT,SOX21,HAS2,HPS5,KLF12,MIER3,TLX1,IGF1,JAK1,KCNA1,KCND2,KCNJ10,KCNN2,KIF5A,CAMK2N2,SFXN5,ARHGAP12,MAP2,MBNL1,CHIC1,LRP1B,SCAMP5,MID1,AFF1,XRRA1,MXI1,MYT1,NBL1,NELL2,NEUROD2,NF1,NFIA,NFIX,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,CCSER2,EPB41L4B,FAT3,MINDY2,PPP3CA,PKIA,PSD,SNRK,PTPRD,RAB5B,CEP97,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,SETD5,RORB,RTN1,RYR3,SALL1,CSRNP3,SCN3A,FAM19A1,HSPA4L,FAM102A,PPP1R9A,KIF16B,CPEB3,CHD9,SLITRK3,SLC1A2,FAM81A,RUFY2,CCDC88A,CPEB4,RIMS1,FAM126B,MYT1L,SOX5,SP4,TEX2,TSPYL2,SMOC1,LARP4,ERBIN,PLCB1,SYN2,SYT1,TACC1,ANKRD12,CAMTA1,CAMSAP2,UNC5D,FBXW11,TBL1X,TCF4,SATB2,DICER1,ZFPM2,AKTIP,THRA,ZFP91,HEY2,RIMBP2,R3HDM1,TRPC1,UBC,FAM155A,UBE3A,SLAIN1,TOM1L2,VLDLR,TBC1D15,PCDH20,REEP1,POLR3H,CA10,MAP3K12,EMSY,MFF,CSDE1,WNK3,SLC17A6,RGS7BP,GOPC,PHTF2,FRMD6,ST8SIA2" MicroRNA hsa-miR-575:mirSVR_lowEffct hsa-miR-575:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.76E-112 2.11E-108 2.86E-111 2.63E-110 309 1376 "CPNE2,RALGAPA1,TTYH1,KCNH8,ASPHD1,ACADM,KDM5D,ADCY2,TMCC3,ADD2,CDC7,SORCS1,AP2A2,PCDH19,KIAA1324,CC2D2A,MRTFA,OGT,LRCH2,EP400,CNIH2,PARG,CACHD1,TNRC6C,ZFYVE28,CCDC74A,NUMB,INSYN2B,SLC4A4,ATP2A2,SLC2A11,ATP6V1G2,BBS2,RGS9,NRP2,BID,BMP7,CDK5R1,SYNJ2,MYRF,CFAP410,CACNA2D1,CACNB2,HAP1,CAMK2A,CH25H,PRC1,CLDN10,LRBA,CDC27,CBARP,SOCS6,JAM2,NDST3,CPNE6,NRXN3,PLAA,COG1,NGEF,HECTD1,IGLON5,IFFO1,BAG4,MYRIP,HS3ST5,CP,CHD1L,SLC35F1,CRMP1,HAPLN1,CRY2,SEC24C,ARHGEF10,NCAN,RIMS4,PDE4DIP,PLXNA4,RASGEF1C,SLC45A1,CTNND1,PUM1,DOCK4,ARHGAP32,DCAF8,PHF19,RIMS3,INTS1,TOMM20,ARMCX2,YTHDC1,DNAJC6,DGCR5,ZBTB24,MYEF2,KIAA0753,PLPPR4,SGSM2,FAM107B,KIF19,OLIG1,SLC12A6,DRP2,PDCD6IP,DTNA,DNM1L,EDN1,PHC2,ANKRD46,EFNB3,EIF5,VPS13B,EPHA5,SRRM1,EFS,CDHR1,PIPOX,RTN3,MRVI1,PTK2B,FDFT1,POLR1B,PRKAG2,HPCAL4,AGAP2,IQCG,NBEA,ERGIC3,NSG2,TVP23A,DKK3,MEGF10,HRASLS5,CHL1,B4GALNT1,ZNF274,DISC1,ATP8A2,ARFIP1,USP19,GLI2,MAP7D2,DCLK2,GPD2,FUT10,STON1,CECR2,GRIA1,DIDO1,SERP2,LINC00839,ATOH8,WIF1,MAEL,RASSF8,TNFAIP8L3,VSIG4,HNF4G,NEGR1,IGSF1,ZNF678,ZNF385B,ITGAV,KCNA1,KCND1,KCNJ3,KCNJ11,KCNK2,KIF5A,LAMP2,STMN1,LMO1,LMO2,FGFBP3,CLEC18A,MAP2,MAP4,MARK1,LDLRAD3,SAMD5,N6AMT1,MTTP,NAP1L1,NEK1,CNOT4,NOVA1,NPTX2,HCN1,NTRK2,OPCML,PBX1,ENPP2,PFKFB3,CDK14,GPSM2,PLXNB3,LRP12,EXOSC10,ING3,POLR2F,PPP2R5C,MASP1,KLK6,BCAS3,SYTL2,CNTLN,PTPRE,PTPRG,PTX3,RAB5B,USP47,NWD1,ZYG11B,MORC4,GTDC1,RGS3,RGS4,SLC25A36,RIC8B,PNMA8A,BAALC,ADAL,ACER3,RPS6KA2,MAP6D1,RTKN,ZNF354C,DGLUCY,SATB1,SCN2B,SCN3A,SCN8A,FNIP1,TNFRSF19,SELL,CASC3,RASA3,KIF16B,ASAP3,CPEB3,MAGI3,CNKSR2,PREX2,SLC2A5,WDR47,ATF7IP,SPHKAP,SLC22A4,SMARCE1,RCOR3,IGSF9B,INAVA,SNRPN,TMCC1,SON,FNBP1,DOK5,CLASP2,ACSBG1,MLC1,PLCB1,SYT1,DDHD2,EXOC7,TBX15,NEU4,ZFP90,TPCN2,DOCK9,RNF216P1,ATP13A2,DNAH7,SIRT1,AP4E1,ARL10,TIAM1,FAM124A,TPM2,SMUG1,TRIO,AMACR,STXBP4,FNDC5,HEPACAM,MEAF6,XPO1,XRCC4,ZNF24,FMN2,GPR158-AS1,SLC26A10,ZNF142,ZBTB38,ANKS1B,ZFAND5,CA10,EMSY,PRDM2,EVI5,LINC02210,RNF103,URM1,KCNAB1,PCBP4,FZD3,HNRNPA3,PHTF2,NUP214,FXR1,SLC4A10" MicroRNA hsa-miR-1915*:mirSVR_lowEffct hsa-miR-1915*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.02E-112 2.82E-108 3.81E-111 3.51E-110 310 1386 "ABAT,SYN3,CSMD2,ADAR,GALNT16,SLC12A5,FZD9,RNF150,KIDINS220,SLC24A4,AK2,SEMA6A,ARHGAP20,KIF6,ZFAT,BCAS1,PPFIA3,APP,MIER1,CDK10,SPTBN4,MARK4,ASTN1,SLC4A4,ATP2B1,N4BP2L1,RIPK1,BCL2L2,BMP7,ARHGEF7,MTMR3,CACNA1I,IL33,CACNB4,CAMK2G,TRIM41,SLC25A14,VXN,ARHGEF25,CBLN1,INA,P2RX6,AIFM1,LRBA,SRSF11,CHN2,B4GALT6,NRXN2,CLTB,IGLON5,AKAP7,BTF3L4,ZNF521,MFSD4A,CP,CHD1L,NCOR2,MROH8,TENM4,ARHGEF10,CTNND2,ECE2,CCDC144A,NOS1AP,ARHGAP24,MATR3,IST1,SCRN1,DBI,DCC,FBXO25,RHOBTB1,SRGAP3,SLC29A4,DNM2,DSCAM,MAMLD1,DYRK1A,E2F6,EDIL3,SEZ6L2,EDNRB,EEF1A2,SYT15,FSD1L,EFNA3,MBNL2,TMEM132E,IRAK4,ELAVL2,ING4,ELAVL4,ELN,EML1,DCTN4,ANKRD13B,SRRM1,SPEG,CDKL3,DUSP27,ACSL4,PTK2B,TOMM40L,FKTN,ZSCAN30,PRMT5,FGF1,FGFR1,MEX3B,FOXF2,SYNCRIP,FLT1,ANKFY1,PSD2,SGIP1,NOP56,DCTN2,EFCAB2,SORBS1,ST6GALNAC3,DLL3,MSANTD4,DOT1L,ABLIM2,MEGF10,ILDR2,JPH4,ATP8A2,GATM,ALDH1L1,TUBGCP4,TUBA8,SULT1C4,MMADHC,TTBK1,TXNL4A,AIFM3,KDM2B,OS9,PCLO,TPPP,PLCD4,GRIN1,GRM7,BTN2A1,LINC00839,CLASRP,FAM19A2,PTPN5,COQ10A,TMEM25,KAT7,MAP4K5,TMEM179,UBE2QL1,VSIG4,HSPA1L,LRRC75A,SMAP1,SOWAHA,RBPJ,DISP2,SCIN,IL6ST,SCRT2,A1BG-AS1,NCOA7,PACRG,SMAD9,MBD1,SYT9,CHIC1,MEF2C,MMP16,MMP17,JAKMIP3,DDX25,CTNNA3,MYO7A,HNRNPM,NF1,NFYA,DNHD1,CLEC9A,PAK3,ZDHHC8,XRN1,SLC25A23,MTRF1L,PNMA3,PMP2,CDIP1,NKAIN4,PKN2,PRKCZ,MAPK4,DCHS2,SAMD9,SLC22A23,DEF8,PIGG,CNTLN,ELOVL2,PTN,PTPRD,PEX5,RAB5B,CEP97,SLC25A48,IQSEC3,FIGN,RGS12,RIC8B,ARMC5,RPE,RPL15,KIAA0895L,SGSM1,TCP11L1,MAPK12,SEMA6D,ATXN7,TRIM46,CASC3,ITSN1,CHD9,ZNF365,SLC1A3,FAM81A,PEX26,DHX30,KANSL3,SLC8A1,SLC9A5,TMEM132D,SLCO1A2,CDK5RAP2,SNRPN,PALLD,FAM219A,SOX1,KDM4C,IDI2-AS1,DDN,SRPK2,CLSTN2,STOX1,DIP2A,STX1A,SYT11,SYNE2,NUDT10,DNAJC9,SYP,TACC1,KAZN,MTCL1,UNC5D,SATB2,CUX2,TRIM2,WDR7,RALYL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,ASXL3,R3HDM1,RBFOX2,TPD52,CDK20,SYNPO2,NEIL2,ZMYND8,FNDC5,UGT8,SLAIN1,FLRT2,BEST1,WRN,RICTOR,LGI4,SF1,PCDH20,ZNF24,TRIM9,ATP6V0E2,ZNF138,CELF4,WNK1,MAP3K12,EMSY,PRDM2,VPS35L,SEMA3B,ITM2C,WIPF2,FZD3,FBXO36,CASC15,CAMK1G,ZNF248,RNF170,SPATA13" MicroRNA hsa-miR-571:mirSVR_lowEffct hsa-miR-571:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.30E-112 2.98E-108 4.02E-111 3.70E-110 306 1352 "CPNE2,RALGAPA1,KCNH8,ABR,EMILIN3,NCKAP5,XKR4,ADCY2,TMCC3,ADD1,BRAP,PLEKHH1,GRAMD1B,SNX30,PTCHD1,ADRA1D,FAHD2CP,DPY19L2P4,MTUS1,KLHL13,PCDH19,TAOK1,ALAD,PCDH10,FAM135A,ZNF687,AMPH,LRFN1,DPP10,UPRT,ALS2,BCAS1,TNRC6C,PPFIA3,AQP4,CDK13,ASPH,TMEM108,MYOM1,RGS9,BMPR1B,CASTOR3,CALB1,CALM1,HAP1,CAST,MAP7,LDB2,SLC5A11,CCNH,UBE2L6,CFL2,ASIC3,EPS15L1,RAB33A,NRXN3,IGFBP7-AS1,CLU,TJP2,NIPBL,AKAP6,SLC25A27,LETMD1,SMARCAL1,MFSD4A,CRMP1,CLIP3,SNCAIP,CSF1R,LRRC3B,MICAL2,GALNT9,CNTNAP2,CST3,PHF14,CTNND1,NRSN1,PPP6R2,FAM131B,CX3CR1,ARHGAP32,TCAF1,EARS2,KCTD8,DGKB,SCRN1,DNAL1,ARMCX4,COPS7A,CEP170,MAGI2,WDR20,CHRDL1,DLG2,GRIN3A,USP3,CD99L2,DTNA,MAMLD1,DNM1L,GOLT1B,E2F6,FCF1,HEYL,CELSR3,PHF20L1,AASS,TUBD1,EPB41,EPB41L1,EPS8,SIRPB1,MRVI1,CHST15,FDFT1,SEC24B,GTF2IRD2,FHL1,RGPD5,FLT1,CAMKK2,NSG1,GABRA3,GAD1,BRPF3,ALDH1L1,GGT7,MSL3,GLUL,AIFM3,FERMT2,ADGRA3,LPAR4,PCLO,GRIA1,GRIA4,CIT,RNFT2,ADAMTS6,SLC2A6,FAM222A,PADI2,HRH3,FRMD3,HMGB1,ZDHHC15,SHISA6,IGF1,KNDC1,HES5,SCRT2,KCNC1,KCNJ11,KHK,KIF5C,KIT,FGFBP3,MAP2,MAP6,MARK1,MBD1,SYT9,MEIS1,KITLG,MOBP,GIT1,N6AMT1,MTTP,HS6ST3,P2RY13,NEK1,NF1,NKX2-2,NOS1,CNOT4,NOVA2,CNTN3,PCSK1,PDE4B,PIRT,PFKFB3,ZNF655,PMP2,PMP22,POLG,PCDHB17P,PRKAB2,PRKCG,MAPK4,PROX1,BCAS3,SLC22A23,WBP1L,MDGA2,EML5,PTPRE,PTPRG,RALGDS,FAT4,FAM184A,RASGRF2,ZDHHC14,MSANTD2,SLC6A15,ZYG11B,RFX5,RIC8B,CARF,NEK11,ARMH4,STK32B,SYNDIG1,ABCA11P,AP1AR,DGLUCY,MAPK12,LRRTM4,SCP2,ZFP2,SOX6,GALNT10,ZFP30,ITSN1,SH3GL3,ARX,AMBRA1,FBXO11,WDR37,ABLIM3,FAM214B,SEPHS1,CCDC88A,SLC11A1,SCMH1,EFHD1,EPC1,IGSF9B,LIMCH1,SCN3B,DOP1A,SON,SP2,NMNAT2,CAND2,PEG10,IQSEC2,RAP1GAP2,DDN,CLSTN2,COLGALT2,ITPRID2,SAMSN1,SS18,ERBIN,ELOVL4,SEPT8,SYNE2,TMEM150C,SYN2,SYP,KAZN,WWC1,IQCE,TBL1X,VWA3A,ZFP90,CUX2,TCF7L2,SZT2,SYNE1,USP32P1,SIK3,DICER1-AS1,THRA,ICAM5,R3HDM1,NPL,RGMB,SYNPO2,TRIO,PDSS1,TRPC3,UBE3A,NSD2,XRCC4,SF1,ZIC3,GPR158-AS1,SLC26A10,ZNF138,ZNF177,DPYSL5,FTSJ1,SYNC,CA10,PRDM2,DNALI1,MPPE1,WNK3,C12orf4,ST7,KAT6A,RNF170,VANGL2,PIANP,NETO1" MicroRNA hsa-miR-654-5p:mirSVR_lowEffct hsa-miR-654-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.03E-112 4.51E-108 6.08E-111 5.60E-110 336 1618 "ASPHD1,ASIC2,FMNL2,ADARB2,GALNT16,TMCC3,ADD1,BRAP,ADORA2A,AP2A2,SPOP,CEP126,SYT13,AMPD2,ANK1,FGD2,CCDC146,LCORL,KCNAB2,DGKZ,DGKD,PHYHD1,AMER3,TNRC6C,PPFIA3,USP37,PRX,MADD,SPTBN4,ZFYVE28,ARHGDIA,CCDC74A,NUMB,DYNLL1,ATP1A2,CADM3,ATP6V0A1,RIPK1,RGS9,BCL7A,CFLAR,KSR1,CDK5R1,LINC00906,C1QC,MYRF,CFAP410,CACNA1A,DDR1,CACNB2,KALRN,HAP1,RUNX1T1,CBS,USP2,ENTPD6,KCNAB3,NUMBL,CACNA2D2,FOXN3,CHGA,ASIC3,CASC2,TAOK2,DLGAP3,RAB33A,CLTC,NGEF,DNAJB5,CNR1,FAM149A,COL11A2,ABI3BP,CP,ZNF385A,AATK,SNCAIP,CSF1R,SEC24C,SLITRK5,GREB1,MYADM,ARHGAP32,PHF19,TM9SF4,INTS1,PHYHIP,PITPNC1,SPOCK3,NTM,TMCC2,SEC16A,SLC29A4,DNM2,DPYSL2,ACOT8,ABI1,TOM1,DYRK1A,USH1C,EFNB3,MBNL2,TNK2,ELN,EN2,EPHA5,RABEPK,SPEG,NRN1,CHST15,FCGRT,ZNF589,SLC9B2,FGF13,FGFR1,TMEM164,POLK,RGPD5,ANKFY1,NOP56,SORBS1,ERGIC3,B3GAT1,TPPP3,FAM120B,B4GALNT1,DISC1,SEPT9,ATP8A2,LRRC37A6P,CYP46A1,GFER,KIRREL3,TNRC6A,MSL3,PCDH11X,OS9,GNAO1,GNAS,GNG3,PRUNE2,GPM6B,TMEM121B,STMN2,GRIA1,GRIA4,GRID1,RFFL,SPACA9,ADAMTS13,GRIN1,GRIN2D,GRM2,GSN,GSTM5,AP4S1,RABL2A,UBE2QL1,HPS5,PADI2,HRH3,HAPLN2,AGBL5,LRRC75A,SHISA6,SMAP1,RBPJ,TMEM240,LRRTM1,NME9,KCNA6,KCNJ11,KCNK1,KCNK3,KCNMA1,KHK,LINC00634,IPO5,TTYH2,LRRC4B,STMN1,LMO1,NCOA7,CLEC18A,MAN2A2,MATN2,MEST,MGAT3,AFDN,MOBP,GIT1,MSI1,MT3,MTTP,LYRM9,MYO7A,FXYD6,NF1,DNHD1,NPTX1,PCBP3,NRGN,NTRK3,GPR88,PAK3,CDK18,PDE4B,BEST3,PFKFB4,PIK3R1,KCTD15,PLEC,PLXNB3,PNMA3,C11orf49,PRRX1,NECAB2,FAT3,POLR2F,FSD1,PPP3CA,NKAIN4,CEP41,MASP1,NDUFS7,WBP1L,LRRC49,WDR25,UHRF1BP1,FAM120C,ZSCAN2,TMEM231,RAB3A,CCDC40,RAP1GAP,ENOX1,ZNF493,OXR1,RASGRF1,DBX2,VEPH1,TRIM68,RFX2,RFX4,KIF7,RNASEL,RNH1,ARMC5,ROBO2,STK32B,WLS,YJEFN3,RYR3,SEMA6D,IL17RB,PEAR1,TRIM46,GALNT10,MRAS,SH3BP2,ITSN1,FAM102A,DOCK10,MAGI3,DZIP1,ZNF365,FAM81A,RPH3A,SMTN,SLC6A8,SLC8A3,SLC11A1,SPHKAP,EPC1,CXXC4,SMARCD3,RIMS1,SNAP25,SNCB,FAM126B,KIF21B,SOX10,ZSWIM8,IDI2-AS1,SPTAN1,DDN,NFASC,LMO3,CLSTN2,ITPRID2,LARP4,SSPO,STAU1,SYT11,ARHGEF9,ADAMTS17,COBL,EXOC7,VWA3A,KIAA0930,AZIN2,TMEM151B,PCDHB15,ARHGEF12,PUM2,TNS2,HIF3A,CYB561A3,DICER1-AS1,TIAM1,CABIN1,RASD2,NPL,TRPC1,TRPM2,DCBLD1,RUSC1,CLEC2L,GORASP1,ZNF709,BCL2L13,PLPPR2,MEAF6,CLIP2,CLDND1,NPDC1,ZSCAN26,FTSJ1,ZNF213,MAP3K12,ITM2C,UBE3B,CASC15,CAMK1G,RNF146,LAS1L" MicroRNA hsa-miR-130b*:mirSVR_highEffct hsa-miR-130b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.50E-112 4.77E-108 6.42E-111 5.92E-110 323 1502 "CLK4,CSMD2,XKR4,CSMD3,KLHL32,GALNT13,ADD3,SORCS1,GRAMD1B,BEND6,NLGN4X,SLC44A5,AP1B1,INTS2,CASKIN1,AK2,SMIM17,CDC42BPA,ANK2,PPFIA1,ANXA7,GPAM,PPFIA3,PPP4R4,ASCL1,CAPRIN2,ASPH,DDX3Y,EIF4G3,STX16,BID,SYNJ1,CACNA1G,GPC2,RAB29,IL33,CA8,CACNB2,KALRN,CAST,CBLN1,CBR1,TMEM257,LRRFIP1,CHN2,CASC2,B4GALT6,KMT2C,IGFBP7-AS1,NRXN1,FAM19A5,ARHGEF6,AKAP7,ARMC8,AKAP6,CP,CHD1L,C2CD2,SH2B1,HAPLN1,CRY2,CLIP3,SNCAIP,LRIG1,FEZ1,ARHGEF10,SIPA1L1,PLXNA4,DZIP3,RIMS2,KATNAL2,TCAF1,RIPOR2,TOX,PHF19,CENPL,MAML1,BRINP1,ARMCX4,DCC,C8orf34,MYEF2,LYPD1,ZC3H11A,GSDME,DDX46,ALKBH8,RHOBTB1,NTM,RABGAP1L,WDR20,CHRDL1,DLG2,RAB39B,DNM1,NYAP1,PDCD6IP,DSCAM,ARRDC4,DTNA,DNM1L,EDN1,EDNRB,SGK2,FCF1,CNNM1,FAM13A,KMT5B,AASS,ELAVL2,PLEKHA1,ELAVL4,PCOLCE2,DCTN4,EMX2,EPB41L2,RABEPK,CEP85L,REEP2,CLVS1,FAM198B,WAC,RPS6KC1,FCGR1A,TOMM40L,FCGRT,OLFM1,CAMSAP1,HPCAL4,AGAP3,ATP13A4,FLT1,TRMO,STAMBP,TPK1,AP4B1,NRG3,ZNF512,OGA,GABRB1,ILDR2,GAD1,FAM120B,JPH4,ZNF559,DISC1,ATP8A2,MYOZ2,LYVE1,GLS,STARD3,GNAS,GPD2,GRB10,GRIA1,PLCD4,GRIN1,GRM7,RNF165,LINGO1,RNFT2,NXPH2,SYNPO,HMGCL,SMAP1,DOCK7,LRRCC1,USP54,KCNB1,KCNC2,KCNJ3,KCNN2,CREG2,KIF5C,KTN1,NCOA7,MBD1,MDM4,SRSF12,MEST,PPM1L,MITF,CD200,COL28A1,MRPL42,ZNF92,CTNNA3,ZNF862,NEUROD2,NF1,NOVA1,DNHD1,NPTX1,SMIM11A,OPCML,GLIPR1L2,PAK3,DPY19L2P2,PCDH9,PDE3A,PDGFRA,PDYN,PIK3CD,FAM218A,RETREG1,PLCL1,PLP1,MTRF1L,PDZRN4,PMP2,SH3KBP1,PPP2R5C,PRKACB,PRKCZ,MAPK9,BCAS3,VPS13C,WBP1L,MDGA2,ANKHD1,BDNF-AS,PXK,PTPRE,PTX3,TTC13,RBBP6,RDX,SLC6A15,GTDC1,TTLL7,ZFHX4,CCDC82,ALG9,CARF,RORB,ELP2,CCDC102B,RPL15,ABCA11P,ST6GALNAC6,NCBP3,SCN2A,SCN3A,ASIC4,SELL,GALNT10,ASRGL1,COPZ1,ITSN1,SH3GL3,CPEB3,NTNG1,FBXO11,FNDC3A,ST3GAL3,SLA,ZNF365,SEPHS1,SLC8A3,ARHGEF40,NAPB,CDK5RAP2,SMARCE1,ANKRD36,LIMCH1,UNC80,SOX1,EMC1,SPP1,KIF1B,NPAS3,LMO3,PBLD,SMOC1,LARP4,MAPK8IP3,FGD4,ARHGEF9,FNDC9,ANKRD28,FAM208A,ANO4,TCEA1,SIN3B,ZEB1,PUM2,FAM200B,THBS4,FBXL16,TMEM9,TLR4,NPL,TPM3,SYNPO2,PDSS1,TRPS1,PPIL6,SSBP2,HEPACAM,TOM1L2,VSNL1,P2RY12,XRCC4,PCDH20,ZIC1,PLPP4,NDRG4,ZBTB16,ZSCAN26,DPYSL5,EMSY,NAV3,PPP1R3F,KCNAB1,FIP1L1,SLC17A6,C12orf4,EPM2A,HRASLS,FBXO36,CASC15,SSPN,SLC4A10" MicroRNA hsa-miR-4322:mirSVR_lowEffct hsa-miR-4322:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.25E-112 5.20E-108 6.99E-111 6.44E-110 320 1476 "CPNE2,RALGAPA1,EMILIN3,SYS1,FAM43B,FMNL2,GALNT16,ADCY2,DSCAML1,SLITRK1,ERMN,ADORA1,ADORA3,GPR158,KCTD16,WDR35,PCDH10,MRTFA,LRFN1,ZFAT,ANK3,CNIH2,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBB1,FAM131A,KIAA1614,SEMA4G,MADD,MARCH3,ATM,ATP1A2,ADGRB2,RGS9,BTK,IL33,KALRN,CAMK2D,TRIM41,RHBDL1,ARHGEF1,ENTPD2,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,SYNPR,NRXN3,KIAA1549L,NMT2,CLTC,QKI,FHL5,CNTFR,IQCK,SMARCAL1,PNKD,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,ARHGEF10,ATRNL1,SDC3,CTH,GREB1,CFAP61,NRSN1,ECE2,BOC,HDAC9,MYADM,ZNF337,IP6K1,DGCR5,ZEB2,HEPH,TIAM2,FBXL5,KIAA0753,COPS7A,SMG7,SV2B,CD99L2,CDON,GNE,ARRDC4,TOM1,EDN1,EDNRB,CACNG7,YAF2,PHF20L1,APH1A,EGFR,KMT5B,SORBS3,IRAK4,ELAVL4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,MRVI1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,FLT1,NOP56,DPYSL4,CINP,CELF1,ST6GALNAC3,KBTBD12,NEURL4,GABRA1,HRASLS5,BRPF3,B4GALNT1,SEPT9,ALDH1L1,TUBGCP4,KIRREL3,TTBK1,ZNF638,MAP7D2,POLL,GNAS,PRUNE2,STON1,MCHR1,GRID1,GRM1,RNF165,FAM107A,ADAMTS6,SCRG1,HMGCL,HNF4G,TLX1,OPALIN,DHX35,HSD17B1,CELF5,MYLK2,LRRC25,USP54,IL11RA,INSM1,C2CD4C,SLC35G1,KCNH2,KCNMA1,SFXN5,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,BCO1,MTTP,MYO5A,MYO7A,FXYD6,NCAM1,NUCB1,OPCML,CLDN11,OXTR,P2RY1,CDK18,NALCN,PIK3CD,FAM218A,CCSER2,PLCB2,MAPKAP1,PRRX1,SPATA6,FA2H,FAT3,POLR2F,PPARA,PRODH,MASP1,RELN,SIDT1,WDR25,ZSCAN2,CCDC40,RALGDS,NWD1,RASGRF1,GTDC1,SEC61A2,RAVER2,CARF,ROBO2,CCDC25,SNX22,SGSM1,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,KCNIP3,WLS,RYR3,LRFN5,SCP2,ASIC4,SELL,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,FERMT1,SHMT2,WDR37,SLC1A3,URGCP,LIMS2,KANSL3,PKNOX2,SLC6A8,SLC6A9,EFHD1,BTBD7,SLC20A2,LGI3,SMARCE1,RIMS1,KIF13A,SNRPN,FAM219A,TSNAXIP1,CLUAP1,SPTAN1,IQSEC2,CLSTN2,SMOC1,ZC4H2,SSPO,MAPK8IP3,SEPT3,GSE1,JMJD6,COBL,TACC1,MTCL1,MLST8,IQCE,TBX15,CLASP1,SZT2,WDR7,SYNE1,FRYL,CYB561A3,GALNT17,TMEM9,ERCC6L2,RIMBP2,TNFRSF1B,C5orf64,CABIN1,TPM4,WBP2,PRMT8,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,VAV2,VLDLR,NSD2,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,PLPP4,GPR158-AS1,NDRG4,ZBTB38,ZNF154,AMZ1,DPYSL5,PCBP1-AS1,ZNF213,DNALI1,LINC00632,WIPF2,TMEM63C,CERS6,ZNF248,RNF170,GAN,JPH3" MicroRNA hsa-miR-25:mirSVR_highEffct hsa-miR-25:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.91E-112 5.57E-108 7.47E-111 6.88E-110 264 1013 "SYN3,RBM10,NCKAP5,CSMD2,CSMD3,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,TXNDC16,C1QTNF3,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,MIER1,ASPH,DDX3Y,ATP2A2,MTMR9,B3GALT2,NOL4,DOCK11,ADAM23,ADGRB3,MPDZ,HCN2,CDK5R1,SYNJ1,CACNA1I,OSGIN2,CA8,KALRN,CAMK2A,MAP7,LDB2,MTMR7,AIFM1,CDC27,CDH10,SOCS6,CHM,NDST3,NRXN3,HECTD1,NIPBL,TMEM155,AKAP6,CNRIP1,HS3ST5,FAM171B,CRHBP,SLC32A1,ATRNL1,SOCS5,FAM169A,SLITRK5,ERC2,APPL1,ST18,EDRF1,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,SACS,G3BP2,DLG2,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,TMEM74,KIAA1109,FHL1,POLK,ATP13A4,SLC37A3,TACC2,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,B4GALNT1,IQGAP2,GAP43,GGTA1P,GHR,SPIN1,GLYR1,PCDH11X,CNDP1,GPD2,GPM6A,GPR12,LPAR4,TPPP,GRIA1,DIDO1,RFFL,GRM1,GRM7,HAS2,UBE2QL1,MIER3,ELOVL5,SCRG1,HNMT,MSL1,USP54,SLC6A17,ITGAV,C2CD4C,KCNK1,LAMP2,LIG4,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,SYT9,LRP1B,MOBP,MOG,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,P2RX7,GPR137C,PAK3,PDE1A,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,PLP1,TRHDE,STRN3,ING3,PPP3CB,CEP41,BDNF-AS,PTPRD,PTPRO,PEX5,TMEM255A,PLEKHB2,ARID4A,BSDC1,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPE65,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,SCN3A,FAM19A1,FNIP1,TRA2B,CPEB3,MYO18A,CHD9,FBXO11,CNKSR2,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PALLD,UNC80,PDZD2,MYCBP2,TEX2,KIF1B,NPAS3,PBLD,ITPRID2,ELOVL4,RGL1,FGD4,SYNE2,SYN2,SYPL1,SYT1,COBL,SYT4,CAMTA1,ANO4,SATB2,SYNE1,DOCK9,SIK3,FAM200B,HHIP,TMPO,KCTD2,CSMD1,TPM4,SYNPO2,TRIO,SGK3,VLDLR,CLDND1,XPO1,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,FMN2,PMEPA1,MFF,PRDM2,LRP8,EVI5,RNF103,NAV3,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,SLC4A10" MicroRNA hsa-miR-190b:mirSVR_highEffct hsa-miR-190b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.36E-111 7.64E-108 1.02E-110 9.44E-110 270 1061 "KLHL32,SLITRK1,DPY19L2P4,ZNF608,KLHL13,TBC1D14,NME5,OSBPL6,LCORL,PHF12,SUGT1P4-STRA6LP-CCDC180,APAF1,GPAM,TNRC6C,MIER1,NCOA1,NUMB,ASTN1,ALDH7A1,ADGRB3,LINC00847,SEC11C,DST,SYNJ1,SCAPER,CA8,CA12,CACNA1D,HIP1R,CERS5,CDC42,CDH18,CLGN,COPB2,RCBTB2,CHRM1,NDST3,NRXN3,PLAA,NRXN1,CNN3,BTF3L4,COL9A2,CPS1,CLOCK,HAPLN1,ANKRD44,SEC24C,SOCS5,PDE4DIP,DZIP3,RIMS2,BOC,KATNAL2,RIPOR2,ARHGAP24,DCAF8,ZEB2,MYEF2,MAGI2,BLOC1S6,PLPPR4,AK5,G3BP2,DMD,CPEB2,DMTF1,ACOT8,DRP2,PDCD6IP,DTNA,ABCC9,EDIL3,EDNRA,RASGRP1,SEMA3D,RBM12,PHF20L1,AASS,KCTD3,PLEKHA1,RGS17,DCTN4,GPHN,NCALD,ETV1,SIRPB1,GMPR2,ABCA8,SH3YL1,TAOK3,FKTN,FDFT1,KAT8,SLC9B2,OLFM1,FGF14,MEX3B,NBEA,SORBS1,UFM1,ATP6V1H,ATP2C1,ZNF605,STAU2,NRG3,PHYHIPL,ZMAT1,MEGF10,CAB39,ZMYND11,ARPP21,GALR1,SALL3,IQGAP2,C15orf41,KIAA1841,DNER,AHDC1,PCDH17,PPARGC1A,MALT1,GK,RND1,CRCP,TOX3,TNRC6A,PCDH11X,PCSK1N,DCLK2,PRUNE2,PCLO,GRIA4,GRIK3,GRM5,AP4S1,GUCY1B1,GYG1,HAS2,MIER3,ELOVL5,ZDHHC15,NEGR1,SMAP1,IRF8,IFI16,ZIC5,RBPJ,PLD5,ITGAM,KCNA4,KIF5C,STXBP5,LIMS1,HECTD2,NCOA7,MATN2,MATN3,LRP1B,POC1B,COL28A1,BLOC1S2,C10orf105,MYO9A,NCAM2,NEUROD1,NF1,HCN1,GPR137C,SNTG1,CNTN3,PAX6,PCDH9,PDE3B,PDPK1,GNG2,OLA1,PLCL1,PCDH18,TRHDE,EPB41L4B,MED1,PPP2R2C,PPP2R5C,GRAMD1C,DIRAS2,MDGA2,BDNF-AS,PTHLH,PTN,TMEM260,SUSD4,ZYG11B,ERI2,RPRD1A,BAALC,ATP8B4,CNTNAP3,RYR3,TRAPPC13,SCN7A,LINC00461,FNIP1,TNFRSF19,SEC14L1,TRA2B,FNDC3A,FHOD3,NLGN1,CTXN2,ZNF365,BTBD3,SEPHS1,SLC14A1,SLC15A2,ZFP1,RCOR3,UNC80,TNIK,HECW1,MYCBP2,KDM4C,MCF2L2,RBM26,NKAIN2,NXT2,RGL1,KLHL7,NUDT10,EXOC7,ANO4,EHBP1,SATB2,ZEB1,WASHC4,DOCK9,TEX15,SIRT1,CRB1,ITGB3BP,AP4E1,SLC44A1,NR2E1,ERCC6L2,FAM124A,BEX4,CSMD1,AMACR,STXBP4,ZMYND8,TSC1,CADM1,OSBP2,ZIC3,ZNF708,TRIM9,CELF4,ZSCAN26,PLPPR5,CA10,PRDM2,CSDE1,ADAMTS9,CIAPIN1,PCDH15,NAV3,C12orf4,RNF170,FRMD6,SOCS4" MicroRNA hsa-miR-634:mirSVR_lowEffct hsa-miR-634:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-111 8.98E-108 1.20E-110 1.11E-109 325 1523 "CPNE2,KCNH8,ACADM,ASIC2,SYS1,METAP1D,NDRG2,CDC7,UNC5A,KIAA1211,SNX30,RNF150,FAHD2CP,SLC24A4,MTUS1,CC2D2A,LRRC7,MARCH4,FAM135A,KIF6,AMT,ANK2,MAP4K3,PPFIA1,PKP4,VAT1L,PPFIA3,APP,PDXK,CASK,CADM3,NOL4,BMPR1B,CDK5R1,BTK,MTMR2,CACNA1G,C5,CACNA1E,CANX,CAPN3,VXN,VSTM2A,TMEM257,SRSF11,CASC2,CNOT8,ARHGAP22,KMT2C,KIAA1549L,QKI,HECTD1,WHRN,BTF3L4,COL11A2,MFSD4A,HAPLN1,HINFP,NCOR1,CSF1,RGS6,LRIG1,FEZ1,ARHGEF10,NCAN,VAC14-AS1,CNTNAP2,APPL1,NRSN1,RUBCN,NOS1AP,MYADM,KATNAL2,DCAF8,TOX,EARS2,LONRF1,TM9SF4,IST1,DAPK1,C8orf34,ZEB2,PLEKHM1,MYEF2,RUSC2,KIAA0319,BLOC1S6,TMCC2,ZNF582-AS1,GRIN3A,DNM2,DMTF1,ABI1,RCAN1,MAMLD1,DNAJB6,DYRK1A,ABCC5,EDN1,TMTC1,RBM12,EGFR,TENM1,USPL1,EPB41,STX2,NCALD,SPEG,MRPL37,TMEM74,DNAJC27,ADGRV1,F8,ZIC4,TESK2,FER,FGFR1,FGFR3,AMOTL2,COQ5,CAMKK2,ATP2C1,PRELID3A,GAD2,RAPGEF6,ALDH1L1,PCDH17,RNPS1,GLI2,DCLK2,LOXL3,GNAS,CECR2,PCLO,RAPGEF4,GRIK2,CLASRP,MFSD2A,ADAMTS6,CELF3,WIF1,C1orf94,FRMD3,HMGCR,HNMT,ZNF491,OPALIN,SMAP1,FAM95B1,GAREM2,RBPJ,USP54,LIX1,ZNF678,INPP5B,ITGA7,SLC35G1,KCNJ10,KCNN1,KCNN2,KCNN3,SYTL4,MAP6,MAT2A,MBP,SYT9,TM6SF1,MDM4,MOG,ERICH3,SAMD5,MSRA,MYO9A,NDP,NFE2L2,NINJ2,NOVA1,NPR2,NTRK2,NUCB2,OPA1,ZDHHC22,ETFRF1,PCSK5,PDE1A,PDGFRA,GNG2,PFKFB2,SSH1,PIK3R1,ZNF655,A2ML1,NLE1,CDIP1,EXOSC10,SCHIP1,ING3,FAT3,POLG,RASGEF1B,CEP41,PROX1,DEF8,MDGA2,PSMD13,UHRF1BP1,PTN,ZSCAN32,OCIAD1,PTPRE,PTPRO,TMEM145,NKAIN1,TMEM255A,RAP1GAP,NWD1,ZCWPW1,ROGDI,ZNF493,RDX,C12orf49,ALG9,GSTCD,ELP2,RPL15,GLDN,ACER3,LRRK2,RTKN,RXRA,SALL1,SEMA6D,ZFP2,CASC3,SFPQ,NLGN4Y,ITSN1,SH3GL3,FBXO11,FHOD3,R3HDM2,ST6GAL1,CLSTN1,FAM81A,PREX2,SLC2A5,SLC8A1,ARHGEF40,SPHKAP,SLIT1,SMARCC2,RIMS1,UNC80,FAM219A,DOP1A,IDI2-AS1,ZC3H13,SPTAN1,ZBTB43,DDN,NFASC,CLSTN2,ITPRID2,SSTR1,LRRC4,NEK4,CEP68,KANK1,JMJD6,TMEM150C,ASTN2,CAMTA1,ADGRL3,TPCN2,WDR7,FAM189A1,AHCYL2,SIK3,TF,ZNF106,AKTIP,GZF1,MTMR14,HEY1,R3HDM1,SEZ6L,WBP2,ZNF384,ZNF346,TRH,RUNDC3B,AMACR,DCBLD1,RUSC1,KCNE5,TSC1,CLHC1,GORASP1,UGT8,PITPNB,PLPPR2,TBC1D15,RICTOR,CFAP298,ZIC1,ZNF711,TRIM9,ATP6V0E2,NDRG4,FTSJ1,ZFAND5,SYNC,CA10,EMSY,RGMA,PPP1R3F,RGS7BP,KAT6A,SMIM8,FAM219B,ADAMTSL3,ZNF248,NHSL1,FXR1,SLC4A10" MicroRNA hsa-miR-363*:mirSVR_lowEffct hsa-miR-363*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-111 9.15E-108 1.22E-110 1.13E-109 338 1640 "CPNE2,SDE2,KCNH8,ASIC1,SYS1,ACTN1,ADAR,GALNT16,ADD1,PNMA8B,UNC5A,FAHD2CP,SPOP,SYT13,MRTFA,AMPH,PPFIA2,CNIH2,SUGT1P4-STRA6LP-CCDC180,CACHD1,TNRC6C,APP,LGR5,SLC7A14,SEMA4G,PRX,LINC00173,MARCH3,NUMB,ATP1A2,ATP2B1,ATP2B2,CARMIL3,SNAI3-AS1,BBS2,RGS9,KSR1,GPC2,SYT6,MAP7,P2RX6,CD86,ARHGEF1,ENTPD2,ENTPD6,LOC730101,SRSF11,NDST3,NMT2,FADS2,HECTD1,MAP4K4,COL11A2,SLC4A8,IGDCC3,SEC31B,AKAP12,CRY2,GDA,RGS6,CSNK1E,RIMS4,CNTNAP2,SLITRK5,ST18,ZSCAN23,CX3CR1,ECE2,CYBB,KIAA0408,GAPVD1,HDAC4,TMEM170A,DAPK1,SCRN1,PITPNC1,MFAP3L,RUSC2,SV2A,SGSM2,RABGAP1L,KBTBD11,GRIN3A,DPP6,DRP2,DTNB,DYRK1A,CNNM1,HEYL,CELSR3,APH1A,ABI2,ASB3,EIF5,PLEKHA1,ELN,DCTN4,EPB41L1,COQ7,STX2,MRPL10,VPS26C,EXTL1,NRN1,F3,REEP2,FKTN,KAT8,POLR1B,FGF11,FGF13,HPCAL4,FLNC,SLC37A3,SYT3,NBEA,CAMKK2,KHDRBS3,GPR153,ADGRA1,BRSK1,GABBR1,GABRA1,B4GALNT1,JPH4,GALR1,ZNF234,IQGAP2,GAP43,AHDC1,GFAP,GHR,MALT1,GLI2,GLRB,MSL3,GNG3,GNG4,GPD1,PRUNE2,CECR2,RAPGEF1,PLCD4,GRIN1,CACFD1,GRIN2D,NR3C1,BTN2A1,ZBTB49,FAM107A,CELF3,UBE2QL1,MAN1B1,ATXN2L,AGBL5,HSPA1L,SMAP1,ATCAY,FAM95B1,RBPJ,DISP2,USP54,INSM1,LRRTM3,LRRTM1,KCNJ5,KCNK1,KCNMA1,A1BG-AS1,STXBP5,KTN1,LIMS1,MAP4,MBD1,SYT9,MDFI,PPM1L,MN1,MOBP,MOV10,GIT1,JAKMIP3,MSR1,MT3,MYO7A,RTL5,MYT1,NHLH1,NINJ2,NKX2-2,NME4,DNHD1,NRGN,NUCB2,OGG1,OPCML,ZDHHC22,PAK3,PDE4A,PDE1B,GNG2,PFKFB3,CAMKV,PKM,FAM216A,PLCB2,PLCD1,FTO,SLC25A23,PURG,PNMA3,PMP2,MAPKAP1,LRP12,RETREG2,POLR2F,POU3F2,TMEM235,RANBP3L,EPDR1,PSD,TMEM104,WDR25,CNTLN,ANKHD1,PTPRB,PTPRE,NKAIN1,PID1,GAL3ST4,DPF2,PRRT2,ERI2,GTDC1,RFX5,RGS12,PRIMA1,KCTD17,RIC8B,MYH14,ROBO2,ELP2,ABCA11P,ZNF331,TRIM46,GALNT10,COPZ1,ITSN1,NTNG1,MAGI3,SEC31A,DZIP1,PPP4R3A,PKNOX2,SLC8A3,ARHGEF40,TRIM67,SCMH1,ATF7IP,CXXC4,SMARCD3,SNAP25,MBD5,SNRPN,PALLD,USP33,SCN3B,SOX2,SOX3,KIF21B,DOK5,CLUAP1,ENKUR,IQSEC2,ZBTB43,NPAS3,DDN,NFASC,C11orf87,CLSTN2,SMOC1,SSTR1,NEK4,DIP2A,KANK1,GSE1,FGD4,RHBDL3,ADAMTS17,SYP,COBL,SLC37A2,SYT5,WWC1,MGRN1,SZT2,PCDHGA11,NAT16,PCDHB9,NSD1,ARHGEF12,TNS2,ATP13A2,DICER1,DICER1-AS1,C18orf54,ACTR6,TNFRSF1B,C5orf64,CABIN1,DCBLD1,KCNE5,SSBP2,SLC35A4,MGAT5B,LMF1,NSD2,WNT7A,SLC13A3,ELFN1,SPHK2,ANKS1B,WNK1,CA10,GDPD5,STMN4,STOX2,SEMA3B,PCDH15,SLC17A7,SNX27,FIP1L1,PCBP4,FAM13C,DOCK8,ST7,CAMK1G,TTC7A" MicroRNA hsa-miR-1284:mirSVR_highEffct hsa-miR-1284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.31E-111 1.30E-107 1.73E-110 1.59E-109 282 1159 "KCNH8,ACADM,CSMD3,NDRG3,FMNL2,AXIN2,PTCHD1,ADRB2,KCTD16,HACE1,HFM1,FAM135A,ANK1,LRCH2,SEMA7A,SMIM29,ALS2,TMEFF1,ZFYVE28,RASL11B,DYNLL1,ATP2A2,ATP2B1,ATP2B2,ALDH7A1,B3GALT2,CARMIL3,ADGRB3,CFLAR,NAE1,SCAPER,JAZF1,OSGIN2,LDLRAD4,CACNB2,CABP7,KALRN,SPAG9,CERS5,CDC42,DIS3L,SRSF11,PLEKHB1,CASC2,NDST3,RAB33A,CLCN3,NRXN1,C4orf33,QKI,HECTD1,NIPBL,SLC25A27,SLC4A8,ACBD5,ZFP28,CREM,ANKRD44,FEZ1,SIPA1L1,VCAN,PDE4DIP,CFAP61,CYBB,BOC,C8orf34,TIAM2,ZC3H11A,SPOCK3,NTM,AK5,WDR20,DLG2,CPEB2,MAMLD1,DNAJB6,E2F5,AASDH,FAM135B,YAF2,PHF20L1,KMT5B,EML1,VPS13B,EPB41L2,GPHN,STX2,EPS8,DENND4A,NCALD,ADGRV1,F3,TAOK3,FKTN,KAT8,SYNCRIP,SORBS1,UFM1,ARFGAP2,ST6GALNAC3,GABRA1,GABRA2,GABRG2,GAD1,ERAP1,MTHFD2,ZNF559,ADAM28,MMADHC,PCDH17,GHR,GLRB,ZNF638,RAB40B,GNAO1,CNDP1,NR3C1,GRM7,FAM19A2,KAT7,ZBTB49,RASSF8,MIER3,HMGB1,HPSE2,ZDHHC15,HSF2,LRRCC1,ZNF678,RIPPLY2,ITPKB,JAK2,KCNC1,KCNQ3,KIT,STMN1,ARHGAP12,PACRG,PIK3AP1,MAP2,MAP6,MARK1,MARK3,LDLRAD3,MEF2C,SRSF12,MEST,MKLN1,ADAM22,MSR1,MYCN,MYO9A,NASP,NCAM1,ZC3H12B,NDP,OTOGL,NODAL,CNOT4,SLC11A2,NRCAM,NTRK3,CHAMP1,OGDH,GPR137C,DPY19L2P2,PCDH8,PCSK2,PDE1C,PDE4B,GNG2,PENK,PIK3C2A,ZNF655,GPSM2,PRIMPOL,STRN3,RC3H2,SCHIP1,ING3,EPB41L4B,PPM1B,PPP2R2C,CRLS1,PPP2R5C,PPP3CB,HYDIN,APTX,SNRK,PTCH1,PTHLH,PTN,TMEM260,QDPR,FAM184A,ENOX1,OXR1,KHDRBS2,MSANTD2,SLC6A15,REV3L,RNASEL,RPRD1A,SETD5,CARF,GSTCD,ROBO2,ROM1,TMEM100,KIAA0895L,PTGR2,NCBP3,TRAPPC13,FAM19A1,SCAF8,KIF21A,ITSN1,NTNG1,FNDC3A,SLITRK3,DHX30,LRRC55,ZNF334,CXXC4,SMARCE1,KIF13A,SNRPN,USP33,DOP1A,TRERF1,SOX2,SPART,TAB2,SMOC1,ERBIN,ZSCAN29,AJAP1,VAMP1,VPS13A,TACC1,CAMTA1,FAM208A,UNC5D,WWC1,ANO4,ACSL6,TRIM2,PCDHB4,ARHGEF12,ZFPM2,TGFBR3,AKTIP,HEY1,DDHD1,TPD52,ZNF384,RGMB,SYNPO2,ANKRD20A2,TMEFF2,EIF4ENIF1,UBE3A,AMOT,PLEKHH2,VLDLR,WIPF1,ZNF781,ZIC2,ZNF711,ZNF17,SMARCAD1,CSDE1,STOX2,NAV3,DOCK8,RTN4,PHTF2,RNF170,SNX14,FRMD6,GAN,SENP7" MicroRNA hsa-miR-4290:mirSVR_lowEffct hsa-miR-4290:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-111 1.33E-107 1.77E-110 1.63E-109 319 1472 "SYN3,SYS1,CSMD2,GALNT16,ADD2,HHATL,SORCS1,MTA3,SLC24A4,KCTD16,SEMA6A,CEP126,LTBP4,PDZD4,PITPNM2,ANK2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBA2,GPAM,PPFIA3,SPTBN4,STK33,PCDHGB4,ATP1A1,CADM3,NOL4,ADAM15,ADGRB1,ADGRB3,BBS2,ARHGEF7,JAZF1,MYRF,CFAP410,CA4,CALB2,KALRN,CAST,BRSK2,ARHGEF25,CBR1,USP6,INA,ARHGEF1,CD81,ARHGEF2,EVI5L,MAGI1,CHGA,TAOK2,ARHGAP22,CLCN4,COG1,MYL6B,TJP2,FADS2,DNAJB5,MAP4K4,GAL3ST1,ZFP28,CNRIP1,C2CD2,NCOR1,SEC24C,MICAL2,CSNK1E,PLXNA4,KIAA0040,ARHGEF4,RUBCN,ZNF337,TM9SF4,DAPK1,CTIF,ARMCX4,ZEB2,B3GAT3,RUSC2,C2CD2L,GSDME,GUCD1,SV2A,TMCC2,EXOG,DMD,ABI1,DTNA,DNAJB6,DYRK1A,ABCC5,FIS1,PHC2,HIPK3,KLHL5,SH3GLB1,FAM13A,APH1A,ABI2,TMEM132E,GOLGA7,RGS17,DCTN4,EPB41,SRRM1,EFS,EZH1,KAT8,GTF2IRD2,OLFM1,FGF13,MAD2L2,AGAP2,EVL,POMT1,TMEM107,ZNF605,ERGIC3,CELF1,B3GAT1,NRG3,GABBR1,ZNF44,CHL1,GABRB3,ZMYND11,DISC1,ALDH1L1,TUBA8,CSDC2,KIRREL3,ZNF276,RND1,CRCP,GLYR1,RAB30,LUZP2,DIPK1C,GRID1,SPACA9,ADAMTS13,GRM7,PTPN5,RABL2A,FAM107A,ATOH8,HLF,AGBL5,TLX1,ICA1,FAM95B1,USP54,IL11RA,INPP5B,SLC6A17,ITPKB,CDH20,KCNB1,KCNJ9,KCNJ11,KCNK2,KCNK3,KCNQ2,A1BG-AS1,MAT2A,ADAM11,PPM1L,MPP2,CPNE9,STK32C,BCO1,MYBPC1,MYH6,HNRNPM,NNAT,VWA2,NTRK3,IGSF11,CLDN11,PCDHGC3,CDK18,PDE3A,PIRT,GNG2,PFKFB2,NLGN3,SERPINE2,PLCB2,PLCL1,FTO,PRIMPOL,POLR2F,PRKAB2,PRKCB,PKN2,WBP1L,WDR25,CNTLN,PXK,PTN,ZSCAN2,QDPR,FAT4,NWD1,RASGRF2,BSDC1,RFX5,RGS12,PBRM1,CYB561D1,MRAP2,SNX22,UEVLD,KIAA0895L,RXRA,FAM192A,SARS,HOGA1,LRRTM4,ASIC4,SLC30A10,TRIM46,CASC3,SHMT2,FHOD3,ST3GAL3,SLC6A8,RAB3GAP1,SLC9A5,SLC12A2,NAPB,SCMH1,NAXD,CXXC4,CDK5RAP2,IFT122,MAPKBP1,SNRPN,UNC80,WDTC1,SOX3,TSNAXIP1,DDN,LHPP,SRPK2,CLSTN2,SSPO,INKA2,MPRIP,CEP68,DIP2A,PHLDB1,KANK1,FAM168A,ZFR2,VAMP1,ARHGEF9,ADGRL3,SATB2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,AKNA,HIF3A,TMEM121,CRB1,LEFTY2,THRA,TK2,DDHD1,TNFRSF1B,TNR,PIK3R5,RBFOX2,C9orf85,TRH,TRPS1,NUTM2A,FNDC5,ANO5,LRTM2,LINC00689,FLRT2,FLRT1,MEAF6,VIPR2,WIPF1,ZNF70,FMN2,PLPP4,CELF4,AMZ1,EML6,MEIS3,PRTFDC1,PRDM8,LMAN2L,KCNAB1,ITM2C,PCBP4,WIPF2,SMIM8,PHTF2,FAM181A,LAS1L" MicroRNA hsa-miR-409-3p:mirSVR_highEffct hsa-miR-409-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-111 1.37E-107 1.82E-110 1.68E-109 291 1233 "KCNH8,CLK4,CSMD3,KLHL32,CCDC85A,ESYT2,KLHL13,ADGRF5,SMIM17,ALCAM,FAM135A,ANK3,MAP4K3,PHF12,ALS2,DDO,API5,APP,LGR5,ASPA,DPY19L3,BACH1,MPDZ,BLM,JAZF1,IL33,MMD2,THSD7A,PTBP2,VXN,CAST,MAP7,CLDN10,KRIT1,AIFM1,LRBA,ARHGAP33,LGI1,MAGI1,CLGN,SOCS6,CHM,NDST3,LHX2,RAB28,C4orf33,HECTD1,NIPBL,AKAP7,AKAP6,AKAP5,ABI3BP,RCHY1,MFSD4A,SLC35F1,CLOCK,ANKRD44,ARHGEF10,CSNK1G3,ATRNL1,PLCH2,VCAN,PHACTR3,PUM1,ST18,USP6NL,KATNAL2,TOX,ZFYVE16,MATR3,KCTD8,PABPC5,ZEB2,CEP170,MAGI2,SACS,SGSM2,CPEB2,ABI1,GNE,DNM1L,ABCC9,E2F5,EDN1,FCF1,EGFR,KMT5B,EGR3,RGS17,LRRC17,KCNMB2,GPHN,STX2,VPS26C,F5,GORAB,SEC24B,SCARA3,IP6K2,ATP13A4,HVCN1,APOPT1,UFM1,PRELID3A,DACH2,STAU2,ADGRA1,GABRA2,GABRB1,GABRG2,ILDR2,GAD2,AHCYL1,SALL3,NCKAP1,ERAP1,ZNF559,DISC1,MYOZ2,GATM,IGSF5,MMADHC,USP19,GHR,MALT1,GK,SPIN1,GLRB,TNRC6A,GNAL,LNX1,GPM6A,FUT10,GPR12,STON1,NUDT21,EML4,CNTRL,GRIA4,GRIK2,NR3C1,GRM1,BTN2A1,LINC01551,HMGB1,AGBL5,HNRNPK,HTR2A,SOWAHA,PLD5,KCNC1,KCNC2,KCNJ3,KCNJ10,KCNJ16,KCNK2,IPO5,LIMS1,PAXBP1,SYTL4,MBNL1,PPM1L,AFDN,ZNF680,MRPL42,BLOC1S2,CTNNA3,NCAM1,NCAM2,RCOR2,NKX2-2,NTRK2,OLR1,OPA1,OXTR,CNTN3,PDE3A,SLC10A4,OLA1,FAM218A,SNX10,GPSM2,JAKMIP1,TRHDE,SCHIP1,NXPH1,PPP2R5E,KANSL1,CEP41,RAB39A,PKN2,HYDIN,RELN,VPS13C,SLC22A23,SIDT1,MDGA2,BDNF-AS,TMEM260,PTPRB,OCIAD1,PTPRD,EML5,PTPRZ1,OXR1,VEPH1,RDX,SEC61A2,RNASEL,ZFHX4,SETD5,C12orf49,RORB,YY1AP1,NEK11,ATP8B4,PRR5L,ABCA11P,SALL1,MIR124-2HG,SCP2,SCAF8,SH3BGR,KIF16B,BTBD7,SLC22A4,SMARCE1,RCOR3,LIMCH1,SNRPN,TNIK,SOX5,CLUAP1,KDM4C,ZC3H13,NPAS3,LMO3,SS18,ERBIN,TTBK2,RGL1,NECAB1,SYN2,SYT1,TAC1,TAL1,CAMSAP2,UNC5D,EHBP1,ZEB1,RPGRIP1L,GPRIN3,RNF175,SIRT1,AP4E1,SLC44A1,ACTR6,TMPO,TPM1,TPM3,RUNDC3B,PRR18,TUBB1,RPRM,SLAIN1,ZNF781,CLDND1,ZIC1,ZNF711,ZNF540,ZNF138,UPF3A,SLC30A4,MFF,RNF103,SCG2,HPS4,FAM47E,WNK3,SLC17A6,FAM13C,DOCK8,HNRNPA3,PHTF2,ACTR3B,NHSL1,SSPN,FRMD6,DPF3,CBLN2,GAN" MicroRNA hsa-miR-340-5p:TargetScan hsa-miR-340-5p TargetScan 2.82E-111 1.58E-107 2.10E-110 1.94E-109 261 994 "ABAT,CLK4,AS3MT,CSMD3,PLEKHG5,ADCY6,GALNT13,BRAP,RNF150,ESYT2,HECW2,OSBPL6,C1QTNF3,ALCAM,ABCD2,BEGAIN,OGT,CDC42BPA,CNTNAP1,GAS7,DGKD,ALS2,LGR5,IGDCC4,CASK,CDK13,NCOA1,RNF182,MTMR9,CADM3,DPY19L3,KIF1A,BCL2L2,DCAF5,CDK5R1,JAZF1,NIPA1,LDLRAD4,CABP7,CALM1,CAMK2A,CAST,BRSK2,MAP7,RUNX1T1,LDB2,KRIT1,C1orf52,DLGAP2,NOG,CFL2,CLCN3,CLTC,ARHGEF6,PCYT1B,ARMC8,MYRIP,NRG2,NSL1,FAM171B,HAPLN1,CRY2,ABCG1,LRIG1,MICAL2,CNTNAP2,SDC3,APPL1,CTH,GREB1,PUM1,FAM131B,PYGO1,KIAA0408,ARHGAP24,MAML1,ELMSAN1,JAKMIP2,MFAP3L,KLHL3,RHOBTB1,DMD,CALN1,NR1D2,CDON,DRP2,DSCAM,EDNRB,EFNA2,PLXNC1,ELAVL2,ELAVL3,CERCAM,ELAVL4,RGS17,EN2,ETV1,DNAJC27,F3,DLC1,MED12L,FGF12,FGR,ANKFY1,ATP2C1,NSG2,B3GAT1,DOT1L,CHL1,GABRB1,BRPF3,NEK6,IQGAP2,FAXC,NFU1,GK,DBF4,GPR75,GLUL,LUZP2,GNAL,GPD2,GPR37,GRID1,RFFL,PRDM5,GRM5,CIT,PTPN5,COQ10A,BVES,PSIP1,HMGB1,HNF4G,NEGR1,AGFG1,DHX35,IGF1,PLD5,IL6ST,DIPK1A,INSM1,C2CD4C,JAK1,KCNA4,KCNB1,KCNJ16,KCNK1,KCNQ3,KIF2A,KIT,LIFR,LIMS1,MAT2A,MATN3,CHIC1,LRP1B,MID1,MITF,DBNL,MXI1,MYO9A,NFE2L2,NFYA,NHLH1,NPTX1,NPTX2,DDR2,IGSF11,OCRL,CLDN11,PBX1,PCSK1,PCSK5,PDE3A,PDGFRA,PIK3C2A,KCTD15,PLCD1,PLCL1,FTO,LRP12,SDK2,FA2H,FAT3,KANSL1,GRAMD1C,PROX1,CNNM2,PTPRB,PTPRG,NKAIN1,RBBP6,RBBP8,REV3L,FIGN,RGS4,NUDT11,RPRD1A,RNH1,RORB,MCMBP,AP1AR,AMER2,SATB1,SCN2A,FAM19A1,FNIP1,HSPA4L,CPEB3,MAGI3,PREX2,EPN2,FAM214B,PKNOX2,LRRC55,ARHGEF40,SCMH1,ATF7IP,MAPKBP1,KIF13A,BDP1,DDN,CLSTN2,NECAB1,C3orf70,ANKRD28,POPDC3,ATP11A,ANKRD12,DDHD2,DNMBP,CAMSAP2,PSD3,PUM2,AP4E1,GPR161,HHIP,FBXL16,ICAM5,DDHD1,DAAM2,KAT6B,RBFOX2,RGMB,NR2C2,ELP5,FRRS1L,FLRT2,LRP8,EVI5,RNF103,KCNAB1,RGS7BP,GOPC,FZD3,HNRNPA3,MSRB3,FRMD6,NETO2,GAN" MicroRNA hsa-miR-152:mirSVR_highEffct hsa-miR-152:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.17E-111 1.78E-107 2.37E-110 2.18E-109 286 1193 "CLK4,ABHD6,FAM43B,TMEM132B,CCDC85A,SLC12A5,AP2A2,HECW2,KCTD16,TXNDC16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,PCDH10,PITPNM2,AMPD3,APBB1,MIER1,ASPH,NCOA1,ATP1A2,STX16,NOL4,ADAM23,ADGRB3,CDK5R1,DST,SYNJ1,OSGIN2,LURAP1,CABP7,CANX,SYT6,CAST,LDB2,CCKBR,USP6,MAGI1,NOG,CFL2,SRSF11,CHI3L2,B4GALT6,PLAA,QKI,MAP4K4,AKAP7,ARMC8,FAM149A,AKAP6,COX4I1,CNRIP1,CHD1L,CLOCK,CS,SEC24C,FEZ2,LRRC3B,ATRNL1,ERC2,CFAP61,CTNND1,ST18,RUBCN,BOC,HDAC9,GAPVD1,MATR3,KIAA0586,TMEM170A,ZNF804A,C8orf34,ZEB2,SNAP91,SACS,NTM,WDR20,DLG2,DLG3,RAB39B,DMPK,DNM2,SLC25A18,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,ELAVL2,STARD3NL,RTN3,TLR7,F3,FCGR1A,FER,MED12L,KIAA1109,OLFM1,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,NPTN,STAU2,NEURL4,STAG2,DKK3,GABRA2,HBS1L,ZNF274,GAP43,C15orf41,KIAA1841,DNER,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,INSM2,RAB40B,GPM6A,CCDC184,PCLO,GRIA1,DIDO1,RNF165,KAT7,LINC01551,MAP4K5,HPS5,TNFAIP8L3,ELOVL5,IGSF1,LIX1,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,C2orf80,MAT2A,MATN3,TM6SF1,PPM1L,MITF,ZNF680,CCDC80,MYO7A,NDP,NEK1,NEUROD1,NF1,CNOT4,DNHD1,NPTX1,NPTX2,PAH,PDE1A,PDE1C,PDYN,PFKFB2,CDK14,GDAP1L1,PIK3C2A,JAKMIP1,PLIN1,TRHDE,EPB41L4B,POU3F2,PPM1B,TATDN3,PTPA,PPP3CA,KANSL1,RASGEF1B,RAB39A,PRKCZ,MAPK7,MAPK10,GRAMD1C,MDGA2,MTMR10,PTHLH,PTPRD,EML5,PTPRN,PPP2R3C,TMEM255A,RALGDS,SH3TC2,FAM184A,RBBP6,SLC25A36,RNASEL,ZFHX4,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,ELP2,PRR5L,YJEFN3,LRRTM4,SCN8A,NTNG1,CHD9,FBXO11,ABLIM3,FAM81A,SLC1A7,BTBD3,WDR47,RUFY2,YPEL4,SPHKAP,SMARCA4,SNRPN,USP33,SOX2,SOX5,ENKUR,ZC3H13,CDK19,SRPK2,ITPRID2,SMOC1,EPB41L3,NKAIN2,NCDN,RGL1,FGD4,VPS13A,SYT4,ATP11A,MTCL1,DDHD2,UNC5D,EHBP1,ZEB1,RPGRIP1L,TCF12,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,TNFRSF1B,TNS1,CADM1,UBTF,BCL2L13,P2RY12,XRCC4,ZBTB14,ZNF24,SPIRE1,SYNC,CA10,CADM2,LINC02210,STOX2,MDH1B,C12orf4,PDSS2,EPM2A,AMN1,ST7,RTN4,FXR1,JPH3" MicroRNA hsa-miR-223:mirSVR_lowEffct hsa-miR-223:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-111 2.02E-107 2.67E-110 2.46E-109 334 1608 "CSMD2,CSMD3,CDC7,ERMN,PWWP2A,BEND6,HACE1,OSBPL1A,OSBPL6,WDR35,TXNDC16,LRRC7,CEP126,FAM135A,GPRASP2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CPNE5,AQP6,PPP4R4,TMEM263,TMEFF1,ZFYVE28,ARNTL,NCOA1,ASTN1,TMEM108,ATP1B3,B3GALT2,DOCK11,TTLL9,BACH1,ADGRB3,SCAPER,WASF1,MYRF,KALRN,CAMK2G,CARS,CBR1,CD86,LRBA,CDH2,CDH8,RAB28,ZFYVE9,COG1,QKI,CNTN1,AKAP5,AHCTF1,MFSD4A,HS3ST5,CRY2,ANKRD44,TRIM69,SNCAIP,SEC24C,CSNK1G3,ATRNL1,PHACTR3,APPL1,CTNND2,NRSN1,RIMS2,PPP6R2,RUBCN,USP6NL,KIAA0408,BOC,DOCK4,HDAC9,GPRASP1,ARHGAP24,HDAC4,ZFYVE16,LIN54,TMEM170A,SPOCK2,DBI,GIT2,YTHDC1,DNAJC6,ZEB2,MFAP3L,KLHL3,POM121,PLPPR4,SRGAP3,NTM,DMD,CPEB2,DOCK2,DMTF1,CASP8AP2,DTNA,EDIL3,TSPAN5,FCF1,MRO,KMT5B,AASS,EIF4G2,EML1,EIF1,GPHN,SRRM1,EPS8,IGSF6,VPS26C,DNAJC27,F8,ABCA8,SH3YL1,EFEMP1,TOMM40L,SYNCRIP,RGPD5,FOXO3,FLT1,PSD2,EFCAB2,NBEA,STAMBP,NPTN,CELF1,DACH2,STAU2,ADGRA1,NEURL4,ZMAT1,GABRB3,GABRG2,RAPGEF6,ARPP21,ALDH1L1,SULT1C4,MSTN,ARFIP1,TCERG1,COPS8,HPGDS,KDM2B,WDFY3-AS2,LILRB4,GPR17,STON1,GPR22,EML4,GPR37,PCLO,GRIA1,GRIA2,GRM7,LINC00839,GSTM5,SOX21,GUCY1A1,HLF,HAPLN2,HNF4G,HTR5A,KIAA1755,USP54,BRINP3,INPP1,KCNC2,KCNJ3,KIF5C,KLC1,ZNF667-AS1,MATN3,MEF2C,MID1,MMP16,MOBP,NRBP2,MTTP,MYO7A,MYT1,NAP1L3,NDUFA5,NELL1,NF1,SLCO1C1,NFIA,NFE2L2,NTRK3,OLR1,OPCML,DPY19L2P2,ETFRF1,PCDH9,PRTG,PDE4A,PDE4D,PIRT,PDGFRA,PDYN,ZNF655,SNX10,JAKMIP1,PLXNB1,ANKRD16,MAPKAP1,LRP12,SCHIP1,SPATA6,MINDY2,PPM1B,PRKACB,CEP41,MAPK4,EPDR1,HYDIN,GDPD1,WBP1L,MDGA2,QRICH1,UHRF1BP1,TMEM260,FAM120C,TMEM231,CEP97,RAD52,FAM66C,ZDHHC14,ERI2,FIGN,RGS3,RIT2,KLHL11,CCDC82,CARF,BAALC,TCP11L1,LGR4,MEG3,WLS,RTKN,SCN2A,SCN8A,TNFRSF19,SUPT20H,NLGN4Y,KIF21A,FAM102A,PPP1R9A,NTNG1,SLC1A3,SLC1A6,RPH3A,RADIL,KBTBD4,SLN,MBD5,KIF13A,SNRPN,TMCC1,MYO16,SON,SOX5,NMNAT2,UHRF1BP1L,SPTB,RBM26,C11orf87,SRPK2,TAB2,CLASP2,ITPRID2,LARP4,SS18,STAU1,NEK4,SEPT8,CEP68,TTBK2,ADHFE1,STXBP1,ACSBG1,SYT11,SYN1,ATP11A,TACC1,MTCL1,DDHD2,CAMTA1,ADGRL3,TBL1X,SMG6,ATMIN,TCF4,ZFP90,CUX2,TCF7,ZEB1,PSD3,PMS2CL,CRB1,ZNF106,SLC44A1,GALNT17,TIAM1,TLL2,TPM3,RGMB,TRPC3,TRPS1,PRR18,CADM1,AMOT,MEAF6,BEST1,TSPAN11,GUSBP1,LGI4,MICU3,ZNF28,KCNT2,SPIRE1,FTSJ1,DHX33,PRDM8,TUBA1A,PCDH15,FZD3,PAK5,HNRNPA3,CASC15,JMJD1C,MSRB3,ZDHHC20,IFT88" MicroRNA hsa-miR-1258:mirSVR_lowEffct hsa-miR-1258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.71E-111 2.08E-107 2.76E-110 2.54E-109 297 1285 "ACLY,SYS1,NDRG2,GALNT13,BRAP,SLC44A5,MTUS1,HFM1,CEP126,ABCD2,PCDH10,FAM135A,CCDC146,USP28,KCNAB2,APBB2,EPB41L5,UPRT,GPAM,APOC2,BCAS1,CPNE5,TMEFF1,ARHGAP5,PLA2G4C,CADPS,DACT3,BRINP2,TMEM108,ATM,SLC4A4,ATP2A2,NOL4,MPDZ,BCHE,BMP7,BSN,MYRF,CACNA1D,CACNA1E,CAMK2D,VSTM2A,CAST,ISPD,INA,ENTPD6,LRBA,CDH8,LHX2,PLAA,CNN3,CNTN1,COL4A5,MFSD4A,NECTIN3,SLC35F1,CREM,RBM39,RNF14,GDA,ABCG1,CSNK1E,KIAA0040,PNPLA8,GREB1,CFAP61,EDRF1,CCDC144A,LONRF1,LIN54,RIMS3,TMEM170A,HEPH,CEP170,SRGAP3,DLG2,DLG3,TRAPPC9,NR1D2,DTNA,MAMLD1,DYRK1A,ABCC9,EDNRA,ATL1,ANKRD46,SEMA3D,FAM13A,ELAVL2,EML1,STARD3NL,GPHN,EPS8,DENND4A,ZNF549,SPEG,RRAGB,KATNAL1,ABCA8,WAC,CACNG3,TMEM132C,GTF2IRD2,FOXO3,FLT1,ANKFY1,SYT3,ATP2C1,ZNF605,DACH2,ST6GALNAC3,MPP6,MEGF10,GABRA1,GABRA5,GABRG2,HBS1L,ARPP21,NCKAP1,ZNF559,ATP8A2,GATM,ALDH1L1,GGT5,LYVE1,GLS,GLUL,CBX1,WDFY3-AS2,GPM6B,ATF7,LPAR4,GPR34,TMEM121B,GRIK2,NR3C1,GRM2,KIF3A,BVES,AP4S1,HAS2,BACH2,ELOVL5,HMGB1,SYNPO,HSPA1L,ZIC5,IL6ST,ITPKB,KCNH1,LAMP2,SYTL4,NCOA7,MAT2A,CHIC1,LRP1B,MEF2C,KCTD6,MITF,MOBP,COL28A1,RSPO2,MYO6,RTL5,NAP1L3,NCAM1,CCDC13,NF1,NFE2L2,CNOT4,SLC11A2,SMIM11A,LOC100128398,OXTR,PCSK5,PCSK2,PDGFRA,BEST3,ZDHHC8,PIK3CD,PIK3R1,XRN1,PLCL1,HMGCLL1,PURG,SCHIP1,ING3,PPM1B,PPP3CB,NKAIN4,PRKACB,MAPK9,HYDIN,WBP1L,APTX,QRICH1,NCR3LG1,TMEM260,RIPOR1,ZSCAN2,QDPR,RASGRF1,DBX2,RFX3,RIC8B,SETD5,EXD2,CCDC25,CCDC102B,ARMH4,UEVLD,MAP6D1,ATAT1,RTN1,FOXRED2,SCN2B,SCN3A,TRIM46,CASC3,SH3GL3,FERMT1,SHC4,FHOD3,ST6GAL1,SLITRK3,ABLIM3,PPP4R3A,FAM214B,KANSL3,SIRT2,SLC9A5,SLC12A2,SLC14A1,EFHD1,SPHKAP,CABCOCO1,SNRPN,TMCC1,KDM4B,SOX3,SP4,CLUAP1,EMC1,UHRF1BP1L,ZBTB43,CLASP2,ZC4H2,NKAIN2,CEP68,GSE1,ARHGEF9,NUDT10,SYPL1,TAC1,TACR1,SEMA4A,DNMBP,FAM208A,ALG1,ZEB1,TRIM2,GPRIN3,SIK3,TEK,FAM200B,CRB1,AP4E1,HHIP,TK2,ACTR6,RIMBP2,TPM3,DOK6,ZNF346,AMACR,STXBP4,TUB,RICTOR,ZIC2,SLC26A10,ZBTB16,TMEM237,AMZ1,ZNF184,EML6,ZNF189,ZNF213,WNK1,TMEM163,WIPF2,SLC17A6,PDSS2,PHTF2,CAMK1G,KLHDC1,NETO1,SENP7" MicroRNA hsa-miR-15b:PITA hsa-miR-15b:PITA_TOP PITA 4.11E-111 2.31E-107 3.04E-110 2.80E-109 228 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,ARHGDIA,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,RTN3,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-15a:PITA hsa-miR-15a:PITA_TOP PITA 4.11E-111 2.31E-107 3.04E-110 2.80E-109 228 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,ARHGDIA,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,RTN3,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-195:PITA hsa-miR-195:PITA_TOP PITA 4.11E-111 2.31E-107 3.04E-110 2.80E-109 228 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,ARHGDIA,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,RTN3,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-497:PITA hsa-miR-497:PITA_TOP PITA 4.11E-111 2.31E-107 3.04E-110 2.80E-109 228 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,ARHGDIA,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,RTN3,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-16:PITA hsa-miR-16:PITA_TOP PITA 4.11E-111 2.31E-107 3.04E-110 2.80E-109 228 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,ARHGDIA,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,RTN3,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-668:mirSVR_lowEffct hsa-miR-668:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.32E-111 2.99E-107 3.92E-110 3.62E-109 300 1312 "ABHD6,ADD3,ADORA2A,PTCHD1,ADRB2,KIDINS220,NLGN4X,LRRC7,ALAD,ARHGAP20,ALK,AMT,PHF12,UPRT,GPAM,ALS2,TNRC6C,AQP4,ARHGDIG,DNAH17,INSYN2B,N4BP2L1,BACH1,RGS9,MTMR3,MMD2,CFAP410,CACNA1A,CACNB2,THSD7A,DIRAS1,CAMK2D,CAMK2G,TRIM41,CANX,CH25H,PRC1,CBS,TMEM257,ENTPD6,AP4M1,CDH8,LARGE1,B4GALT6,NDST3,LSMEM2,NRXN1,FAM189A2,TJP2,MAP4K4,COL4A5,SUMF2,SEC31B,HAPLN1,RGS6,NCAN,RIMS4,GREB1,RUBCN,TCAF1,ZFYVE16,LONRF1,TMEM170A,DCC,ARMCX2,ZEB2,COPS7A,TMEM130,LYPD1,G3BP2,WDR20,KIF19,ZNF582-AS1,RAB39B,DOCK2,CASP8AP2,DRD1,ABI1,PDCD6IP,DYRK1A,E2F5,EBF1,CNNM1,HEYL,FSD1L,GPR61,PHF20L1,ABI2,GOLGA7,KCTD3,EPB41,SRRM1,ZNF549,ARMCX1,AMZ2,CHST15,FKTN,STRADA,FER,FGF13,PRKAG2,FOXG1,SLC37A3,C2orf88,EFCAB2,NBEA,ATP2C1,NSG2,GPR153,MPP6,ZNF512,GABRA2,ARPP21,NEK6,GAP43,DISC1,GCNT2,GDF9,GGT7,MALT1,GK,ZNF276,ZNF638,KIAA1958,MAP7D2,DCLK2,GPM6A,RAPGEF4,NR3C1,GRM2,GUCY1B1,MUM1,RASSF8,C1orf94,PACSIN2,MIER3,USP51,FAM95B1,USP54,SCIN,INPP5B,INSM1,SLC35G1,KCNJ5,KCNJ10,KCNN2,KCNN3,STXBP5,LIFR,SYTL4,HECTD2,MAPT,AQP11,MBP,MDM4,KITLG,MITF,AFDN,MOG,GIT1,SAMD5,CTNNA3,RTL5,FXYD6,NELL2,OTOGL,NKX2-2,NOVA2,DNHD1,NPTX2,ODF2,OXTR,P2RX7,PCSK1,PCSK2,PDE3B,GPR85,CDK14,ZNF655,FAM216A,HMGCLL1,PDZRN4,MAPKAP1,LRP12,FAT3,MED1,CRLS1,PPP2R5C,PRKAB2,PRKCB,PRPSAP2,RELN,LRRC49,SIDT1,DEF8,SNRK,QRICH1,CNTLN,OCIAD1,PTPRH,ZNF793,NWD1,OXR1,RASGRF2,RADX,RDX,ZYG11B,TRIM68,GTDC1,RFX3,RGS3,RLBP1,SEC61A2,CCDC25,RPE65,NEK11,FBXW7,ACER3,MEG3,WLS,SOX6,NLGN4Y,FNDC3A,ST3GAL3,BTBD3,RAB3GAP1,ARHGEF40,EFHD1,ARFGAP1,NAXD,ANKRD36,KIF13A,SNRPN,FAM126B,USP33,DOP1A,PDZD2,SOX10,SP2,PEG10,KIF1B,ZBTB43,TSPYL2,PBLD,COLGALT2,NCDN,KANK1,FGD4,VPS13A,ARC,SYP,CAMTA1,ALG1,ANO4,VWA3A,KIAA0930,CUX2,TPCN2,CLASP1,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,FAM200B,GALNT17,R3HDM1,SEZ6L,TPD52,TPM2,METTL3,PRMT8,DCBLD1,TTPA,RPRM,UBE2H,SLC35A4,UGT8,FLRT1,WIPF1,NSD2,GUSBP1,ZNF28,ATP6V0E2,FMN2,ZBTB38,TMEM237,WNK1,STOX2,ADAMTS9,SIGLEC10,PCDH15,FIP1L1,DNAH10,ZDHHC20,SLC39A12" MicroRNA hsa-miR-148b:mirSVR_highEffct hsa-miR-148b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.41E-111 3.04E-107 3.99E-110 3.67E-109 284 1179 "CLK4,FAM43B,TMEM132B,CCDC85A,SLC12A5,AP2A2,HECW2,KCTD16,TXNDC16,AK2,ADGRF5,SMIM17,ALCAM,ABCD2,MARCH4,PCDH10,PITPNM2,AMPD3,USP28,APBB1,MIER1,LINC00173,ASPH,NCOA1,ATP1A2,STX16,ATP2B1,NOL4,ADAM23,ADGRB3,CDK5R1,DST,SYNJ1,GPC2,LURAP1,CABP7,CANX,SYT6,CAST,CCKBR,USP6,MAGI1,NOG,CFL2,SRSF11,SYNPR,B4GALT6,PLAA,QKI,MAP4K4,AKAP7,ARMC8,FAM149A,CNRIP1,CLOCK,SEC24C,FEZ2,OSBPL3,ATRNL1,ERC2,CFAP61,CTNND1,ST18,RUBCN,BOC,HDAC9,GAPVD1,KIAA0586,TMEM170A,ZNF804A,C8orf34,ZEB2,SNAP91,SACS,NTM,WDR20,DLG2,DLG3,RAB39B,DMPK,DNM2,GOLT1B,FCF1,RASGRP1,KLHL5,FRY,PHF20L1,EGR3,COPS4,ELAVL2,TNK2,RTN3,TLR7,F3,ACSL4,SCML2,FCGR1A,FER,MED12L,FGF14,PRKAG2,SUCO,VTI1B,SYNCRIP,FLT1,HVCN1,NPTN,ATP2C1,TVP23A,NEURL4,STAG2,DKK3,GABRA1,GABRA2,HBS1L,ZNF274,GAP43,C15orf41,DISC1,KIAA1841,DNER,GCNT2,ARFIP1,WASHC2A,AHDC1,ADAM28,PPARGC1A,TNRC6A,MAP7D2,INSM2,RAB40B,GPM6A,PCLO,GRIA1,DIDO1,BTN2A1,RNF165,KAT7,HPS5,TNFAIP8L3,ELOVL5,IGSF1,LIX1,KCNK2,KCNN2,KCNN3,KIT,STXBP5,LAMP2,LIG4,NCOA7,C2orf80,MAT2A,MATN3,MBD1,TM6SF1,PPM1L,MITF,ZNF680,MYO7A,NDP,NEUROD1,NF1,CNOT4,DNHD1,NPTX1,NPTX2,GPR137C,PCDH9,PDE1A,PDE1C,PDYN,PFKFB2,CDK14,GDAP1L1,PIK3C2A,JAKMIP1,PLIN1,HMGCLL1,TRHDE,POU3F2,TATDN3,PTPA,PPP3CA,KANSL1,RASGEF1B,RAB39A,PRKCZ,MAPK7,MAPK10,GRAMD1C,SNRK,MDGA2,MTMR10,PTHLH,PTN,PTPRD,EML5,PPP2R3C,TMEM255A,SH3TC2,FAM184A,RBBP6,DPF2,SLC25A36,RNASEL,ZFHX4,CCDC82,PNMA8A,ROBO1,ROBO2,RORB,ELP2,PRR5L,RTKN,YJEFN3,LRRTM4,FAM19A1,SFPQ,NTNG1,CHD9,FBXO11,FAM81A,SLC1A7,BTBD3,WDR47,RUFY2,SMARCA4,LMBRD1,SNRPN,UNC80,USP33,SOX5,SP4,ZC3H13,CDK19,SRPK2,ITPRID2,SMOC1,EPB41L3,NKAIN2,RGL1,FGD4,VPS13A,SYT4,ATP11A,MTCL1,DDHD2,UNC5D,ZEB1,RPGRIP1L,TCF12,WDR7,USP32P1,FRYL,TEK,DICER1,ZFPM2,AP4E1,AKTIP,SLC44A1,FBXL16,TJP1,TNFRSF1B,TNS1,TPM1,TRPC3,CADM1,VLDLR,P2RY12,XRCC4,ZNF24,SPIRE1,SYNC,LINC02210,STOX2,MDH1B,C12orf4,EPM2A,AMN1,ST7,RTN4,FXR1,JPH3" MicroRNA hsa-miR-411:mirSVR_lowEffct hsa-miR-411:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.44E-111 3.06E-107 4.01E-110 3.69E-109 295 1270 "SDE2,ASPHD1,NDRG3,AXIN2,SORCS1,PTCHD1,AP1B1,OSBPL1A,CC2D2A,LRRC7,SRPX,BBOX1,GOLGA7B,FAM135A,APBA2,APC,EPB41L5,ALS2,LRRC4C,API5,PPFIA3,ARHGAP5,PLA2G4C,NUMB,TMEM108,ATM,ATP1A2,RNF182,MTMR9,NOL4,ADGRB3,BBS2,DST,LINC00906,BTK,CACNA1G,C5,MYRF,IL33,CA8,CACNB4,CALB1,CAMK2G,SPAG9,METTL6,DGKI,LRBA,MAGI1,CDO1,NOG,ADGRG1,SRSF11,CHM,KIAA1549L,ABCG2,MAP4K4,NIPBL,AKAP5,ABI3BP,CNRIP1,HS3ST5,CREM,SNCAIP,FEZ2,PHF14,HDAC9,ZNF337,TMEM170A,AIF1L,YTHDC1,C8orf34,ZEB2,HP1BP3,ZC3H11A,RHOBTB1,PLPPR4,SV2B,RABGAP1L,CCDC3,DMD,RPS6KL1,ACOT8,DTNB,ECM2,DYRK1A,DNM1L,ABCC9,GOLT1B,WDPCP,ATL1,YAF2,PHF20L1,GOLGA7,CALCRL,VPS13B,EPB41L2,RCAN2,LRRC17,KCNMB2,GPHN,CDHR1,TMEM74,ETV1,EYA1,MRVI1,SCML2,FCGR1A,CEP78,FER,CAMSAP1,POLK,FOXG1,SEMA4D,FLT1,SYT3,FAM49B,ERGIC3,KHDRBS3,DACH2,NRG3,MPP6,PHYHIPL,GABRA1,CHL1,TRAF3IP2,GALC,RAPGEF6,NCKAP1,MTHFD2,KIAA1841,GATM,SULT1C4,GK,MAP7D2,LUZP2,FERMT2,ZNF496,KAT7,FAM222A,TNFAIP8L3,AGBL5,NEGR1,LRRC75A,BRINP3,NME9,JAK2,METTL21A,KIF2A,KIF5A,LINC00634,KLRC3,KLC1,CYP27C1,KTN1,L1CAM,STMN1,MAN2A2,MAP4,MARK1,MATN2,MATN3,MBNL1,MOG,CD200,SAMD5,CTNNA3,MYO7A,MYO9A,NCAM1,NDUFA5,DNHD1,SMIM11A,NUMA1,SETD4,OGDH,CNTN3,PAX6,PBX1,PDE3B,CDK14,ZNF655,PKD1,PCDH18,SMIM7,HMGCLL1,PURG,PDZRN4,PMP2,TRHDE,LRP12,PSAT1,MAGEL2,MAPK9,HYDIN,RELN,CNTLN,PTAFR,MTMR10,PTN,PTPN13,PTPRE,PTPRG,PTPRH,PTX3,ZNF793,FAT4,RFX4,RFX5,RIC8B,PBRM1,ROBO2,ZC3H14,KIAA0895L,PRR5L,LRRK2,HSD11B1L,ATAT1,CLIP1,FAM192A,ELMOD1,SH3GL3,FRMPD1,MYO18A,SYBU,SLC12A4,BTBD7,CPEB4,ZKSCAN3,MAST1,SORCS3,SMARCE1,ANKRD36,MBD5,PALLD,TMCC1,SON,PDZD2,SOX11,ZC3H13,RBM26,C11orf87,CLASP2,STOX1,ZC4H2,SS18,SEPT3,VPS13A,ATP11A,CAMSAP2,TMEM136,VWA3A,EHBP1,ACSL6,KIAA0930,CUX2,PCDHB15,PCDHB10,PCDHB3,SIRT1,ZFPM2,AP4E1,TIAM1,HEY2,DAAM2,ZNF384,STXBP4,TRPC1,TRPS1,RUSC1,TTTY15,TTPA,CADM1,RPL7L1,UGT8,PLEKHH2,VLDLR,LMF1,VSNL1,CLIP2,ZNF711,ZBTB38,FSTL5,ZNF184,DNALI1,PRDM8,RNF103,ADAMTS9,NAV3,PLSCR4,C12orf4,HNRNPA3,JMJD1C,ZNF248,TIGD6,CPNE4" MicroRNA hsa-miR-337-3p:mirSVR_lowEffct hsa-miR-337-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.83E-111 3.84E-107 5.02E-110 4.63E-109 292 1246 "SDE2,SYN3,NBAT1,ACTN1,XKR4,CSMD3,KLHL32,ADD2,USP31,KIAA1211,MTUS1,RTL9,SORCS2,OSBPL8,ARHGAP20,LRCH2,MAP4K3,PKP4,APBB2,ALS2,USP37,ASCL1,STK33,MARK4,EIF4G3,SNAI3-AS1,CFLAR,BMP7,FUBP1,JAZF1,NIPA1,CFAP410,ISPD,MAP7,USP6,P2RX6,CD38,DGKI,CCPG1,COPB2,CHN1,CASC2,B4GALT6,NMT2,MAP4K4,CNN3,ARHGEF6,CNR1,IQCK,BAG4,ZFP28,NRG2,CRHBP,CREB5,GDA,SEC24C,LRIG1,CST3,SLITRK5,KIAA0040,APPL1,PLCXD3,NRSN1,RIMS2,ECE2,ARHGAP32,GAPVD1,FRMPD4,TOX,KCTD8,DGKB,TOMM20,GIT2,YTHDC1,ZNF804A,CEP170,SMG7,PLPPR4,SNAP91,SV2B,KBTBD11,GRIN3A,RAB39B,USP3,DNM2,DRD1,DTNA,DNAJB6,GOLT1B,EBF1,ANKRD46,SYT15,KLHL5,TMTC1,YAF2,PHF20L1,RASA4,AASS,TENM1,PAN3,ENPP6,ERBB4,EXTL2,AMZ2,FKTN,KAT8,GORAB,CAMSAP1,HPCAL4,FOXG1,SEC23B,PCYOX1,SYNCRIP,SEMA4D,ATP13A4,SORBS1,TMEM107,PDLIM5,GAB1,HRASLS5,CHL1,GABRG1,TRAF3IP2,NCKAP1,ACSS1,ARFIP1,ADAM28,TCERG1,RAB30,PCDH11X,ZNF638,LUZP2,FERMT2,GPD2,LPAR4,GPR37,CECR2,NR3C1,GRM5,GRM8,LINC00839,ZBTB49,IRAK3,RASSF8,SYNPO,ZDHHC15,SMAP1,IGF1,SCIN,HES5,KCNC1,KCNC2,KCNJ9,STXBP5,CYP27C1,LAMP2,LIFR,LIMS1,ARHGAP12,NCOA7,ZFYVE27,MATN2,IL17D,CHIC1,TM6SF1,MEF2C,MEIS1,MITF,MOBP,ZNF680,JAKMIP3,MSRA,SCG3,ZNF92,MYO6,MYO9A,NF1,HCN1,OXTR,ETFRF1,PCSK5,PDPK1,PFKFB2,GDAP1L1,STRN3,LRP12,SH3KBP1,MINDY2,PPP2R5C,PPP2R5E,RANBP3L,EPDR1,SAMD9,UHRF1BP1,PTN,TMEM260,PTPN13,PTPRB,PTPRD,C1orf109,ZSCAN2,OXR1,DBX2,KHDRBS2,CRTAC1,RET,ERI2,RFX4,RGS12,ALG9,PCMTD2,RPE65,TMEM100,RPL15,KIAA0895L,MCMBP,LRRK2,ABCA11P,ATAT1,ATXN2,FNIP1,ASRGL1,PPP1R9A,NLGN1,SLC8A1,SLC8A3,ELMO2,BTBD7,ANKRD36,RIMS1,SNAP25,SNCA,MBD5,TMCC1,UNC80,SOX5,FNBP1,MYCBP2,SPP1,TSPYL2,C11orf87,LARP4,NKAIN2,ERBIN,SYT11,PLCB1,SYN2,C12orf76,UNC5D,KIAA1107,WWC1,KLHL4,ATMIN,ACSL6,TCF4,TRIM2,TCF12,PCDHGB7,DOCK9,TGFBR3,ZNF106,TMOD1,RGMB,ZNF346,PPIL6,SSBP2,HIRA,RPL7L1,FAM155A,AMOT,VLDLR,SF1,ZFP37,FMN2,GPR158-AS1,REEP1,POLR3H,ANKS1B,FTSJ1,PLPPR5,WNK1,PRDM2,CSDE1,STOX2,RNF103,PCDH15,URM1,FAM47E,MPPE1,PLSCR4,ACTR3B,VANGL2" MicroRNA hsa-miR-1193:mirSVR_lowEffct hsa-miR-1193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.32E-111 4.11E-107 5.37E-110 4.95E-109 291 1238 "ASIC1,ACTN1,CSMD2,XKR4,PSMG3-AS1,KLRC4,GALNT13,ADD1,ADRB2,AP2A2,AP1B1,MTUS1,HECW2,RTL9,KIAA1324,OSBPL6,TXNDC16,SYT13,ZFAT,PI16,PPFIA2,SUGT1P4-STRA6LP-CCDC180,APC,APLP1,MAGEE2,GPAM,BCAS1,LINC00173,PCDHGB4,DYNLL1,ATP2B1,N4BP2L1,RIPK1,ADGRB3,BARD1,DCAF5,NRP2,CFLAR,BMP7,CDK5R1,IL33,CABP7,PTBP2,CAPN3,CAST,SPAG9,CCNH,ZBED1,ARHGAP33,LGI1,TIGD7,DIS3L,ASIC3,CASC2,SYNPR,PPT2,CLCN3,C4orf33,SRP14-AS1,ARHGEF6,COL9A1,SLC4A7,SMARCAL1,PNKD,SEC31B,CLOCK,ENTPD4,CRHBP,CRY2,GDA,CS,SNCAIP,TENM4,LRRC3B,OSBPL3,PLXNA4,ERC2,UBXN2A,CTNND2,NRSN1,DCAF4,CCDC144A,DCAF8,TOX,RASSF2,MATR3,KCTD8,DGKG,TOMM20,PITPNC1,ZEB2,GUCD1,PLPPR4,ARNT2,DNM1,USP3,DOCK2,DPP6,SLC25A18,PDCD6IP,DYRK1A,FARSB,EDN1,EDN3,CACNG7,ABI2,ELAVL3,MTSS1L,EPHB1,SPEG,MRPL10,ADGRV1,FAM198B,ZNF585B,TOMM40L,FCGRT,STRADA,FDFT1,SLC9B2,FGF11,FGFR1,AMOTL2,POLK,ABLIM2,PHYHIPL,STAG2,MEGF10,DENND2A,HBS1L,IP6K3,ZNF559,GATM,SULT1C4,DBF4,TOX3,PCDH11X,OS9,LUZP2,CNDP1,NUDT21,CACFD1,KAT7,AP4S1,RASSF8,TOX2,MIER3,HLF,HMGCL,AGBL5,NEGR1,LRRC75A,HSP90AA1,NKD1,SCIN,ITGA7,SLC35G1,KCNA6,KCND1,KCNJ3,SYTL4,LOC100128239,MAP4,MEIS1,PPM1L,MPP2,MSI1,MSR1,MXI1,MYT1,NCAM1,SFR1,NFIA,ALDH1L2,CNOT4,NPTX2,NRCAM,NTRK3,NUCB2,OPA1,OPCML,PCDHGC3,PCDH9,PFKFB4,HERC2P3,GDAP1L1,ASPDH,PLXNB1,PURG,PMP22,SCHIP1,PILRA,VSTM2L,PRKCG,PRKCZ,DIRAS2,BCAS3,CYBC1,PSMA6,SNRK,QRICH1,WDR25,PTAFR,OCIAD1,PTPRE,PTPRH,USP47,FAM66C,RALGDS,IQSEC3,CRTAC1,RFX4,SLC25A36,RIC8B,RPRD1A,ALG9,PNMA8A,MCMBP,GLDN,TCP11L1,ZNF568,FOXRED2,SCP2,SELL,MRAS,SH3BGR,SLC1A3,SLC6A1,SLC6A8,ATF7IP,SLC22A4,MAST1,RCOR3,RIMS1,MBD5,CABCOCO1,FAM126B,WDTC1,SOX2,TSNAXIP1,SOX10,KDM3A,TEX2,KIF1B,DDN,NFASC,LHPP,POGZ,ITPRID2,RGL1,NSFL1C,FAM168A,ZFR2,SYN1,TACR1,ZFP90,TCF7,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PMS2CL,DICER1-AS1,MTMR14,TLR4,HEY2,TMOD1,CSMD1,KAT6B,SEZ6L,AMACR,RUSC1,SLC35A4,BEST1,ZNF708,AGMO,STMN4,LMAN2L,ADAMTS9,PDSS2,UBE3B,FBXO36,FAM219B" MicroRNA hsa-miR-515-3p:mirSVR_lowEffct hsa-miR-515-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-110 6.26E-107 8.17E-110 7.52E-109 301 1324 "EMILIN3,SYS1,CSMD3,ADCY2,GALNT13,ADD2,KIAA1211,PTCHD1,AK2,SYT13,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB1,APC,VAT1L,SHTN1,CDC14B,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,CAPRIN2,CHRD,DDX3Y,ATP2A2,B3GALT2,RIPK1,TTLL9,LINC00847,RGS9,DCAF5,BID,SYNJ2,RAB29,CDK5R2,CACNB4,HAP1,CAMK2G,SLC25A14,VXN,SPAG9,CCKBR,CERS5,ARHGEF1,SCARB1,CD38,SEPT7,LGI1,MAGI1,ASIC3,CHN2,CASC2,RAB28,SLC24A2,STOML1,FBXO7,FAM189A2,TJP2,QKI,SRP14-AS1,WHRN,SLC35F1,GDA,TRIM69,RGS6,FEZ2,FEZ1,CTH,EDRF1,MAML1,IST1,GIT2,YTHDC1,ZNF804A,ZEB2,KIAA0753,CEP170,SV2B,NTM,DMD,DMTF1,DPH1,DYRK1A,EDN1,PHC2,ANKRD46,SYT15,CNNM1,SEMA3D,FAM13A,PLXNC1,CERCAM,EMX2,ERCC2,VPS26C,ANKMY1,GMPR2,HSPA12B,ZNF585B,FCGRT,ZSCAN30,KIAA1109,FGF1,FGF11,SLC37A3,FOLH1,C2orf88,NBEA,ARFGAP2,ADGRA1,AP4B1,PHYHIPL,GABRA2,GABRB3,CAB39,JPH4,GALR1,GHDC,ERAP1,LRRC37A6P,NEU3,TUBA8,MSTN,KIRREL3,TOX3,RAB40B,STON1,GRIA1,SERP2,KIF3A,LINC00839,LINGO1,GUCY1B1,SLC2A6,IGSF21,C1orf94,PTGDR2,IDH3A,DOCK7,TJAP1,IGSF1,IL6ST,JAK1,KCNA1,KCNJ11,KCNK1,KCNK2,KIT,KTN1,LAMP2,STMN1,FGFBP3,GPR155,LRP1B,SAMD5,ADAM22,MSR1,NRBP2,MTTP,MTR,MYO5A,HNRNPM,FXYD6,ZC3H12B,NOS1,DNHD1,SLC11A2,P2RX7,GPR137C,PBX1,PDE1B,PDYN,PFKFB4,DUSP26,XRN1,NLE1,PLIN1,SLC25A23,PCDH18,SCHIP1,SLC36A4,FAT3,FSD1,PPP2R5E,PPP3CB,HYDIN,DIRAS2,SIDT1,GON4L,MDGA2,UHRF1BP1,MTMR10,PTHLH,ELOVL2,OCIAD1,PTPRE,TMEM255A,FAM184A,BSDC1,GTDC1,SLC25A36,LGI2,ALG9,ARMC5,CCDC25,NEK11,SPIN3,ATP8B4,TCP11L1,EMID1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,TRAPPC13,SEMA6D,DRAXIN,ATXN2,ATXN7,HOGA1,TNFRSF19,SLC30A10,PEAR1,CASC3,MRAS,SUPT20H,ASAP3,SHMT2,MAGI3,CHD9,CTXN2,PAAF1,SLC1A3,YPEL4,SLC8A3,ELMO2,CPEB4,OGDHL,SMARCD3,MYH15,KIF13A,SNRPN,UNC80,USP33,SCN3B,TNIK,NMNAT2,SPART,C11orf87,SRPK2,STOX1,NEK4,RGL1,MLC1,C12orf76,TBL1X,TMEM136,SIN3B,TCF7L2,TRIM2,PHF24,FRYL,AHCYL2,DICER1,ZFPM2,CRB1,GALNT17,ZFP91,LRRC8A,KCTD2,TP53BP2,STXBP4,SGK3,HEPACAM,CADM1,RPL7L1,UCHL1,UGT8,SLAIN1,CCDC14,TBC1D15,GUSBP1,XPO1,ZNF711,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,PRDM2,STOX2,EPM2A,RGS7BP,GOPC,DOCK8,RTN4,TRAM2-AS1,RNF170,PIANP,SENP7" MicroRNA hsa-miR-921:mirSVR_lowEffct hsa-miR-921:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-110 8.27E-107 1.08E-109 9.93E-109 312 1420 "PLEKHH1,PTCHD1,HECW2,KLHL13,KIAA1324,TXNDC16,HFM1,LRRC7,ALAD,AMPD2,AMPD3,APBB1,EPB41L5,GPAM,ALS2,AMER3,LGR5,SFMBT2,ARNTL,PLA2G4C,ASPH,ATM,ATP1A2,ATP2B2,B3GALT2,DPY19L3,ATP6V0A1,DCAF5,CFLAR,KSR1,ARHGEF7,FUBP1,LINC00906,C5,CACNA1D,LURAP1,KALRN,PTBP2,VSTM2A,CAST,CBLN1,SLC16A4,CD38,ENTPD6,LRBA,REPS2,CDH2,DCLK1,LGI1,CCPG1,CACNA2D2,FOXN3,ASIC3,SYNPR,RAB28,PPT2,NRXN1,COG1,CLTB,CNTN1,BTF3L4,LETMD1,COL11A2,AKAP5,BAG4,PREPL,CREM,RBM39,CREB5,ANKRD44,GDA,CS,SNCAIP,RASGEF1C,SLITRK5,DZIP3,NRSN1,RIMS2,ST18,DCAF4,ARHGAP24,EARS2,RASSF2,GIT2,YTHDC1,ZEB2,RABGAP1L,WDR20,ZNF582-AS1,EXOG,GRIN3A,RAB39B,SLC29A4,DYNC1I1,CDON,DRP2,PDCD6IP,ECM2,MAMLD1,DNAJB6,DNM1L,EBF1,HIPK3,FCF1,RASGRP1,FSD1L,EIF1,OLIG2,VPS13B,DMTN,EPHA5,KATNAL1,F3,FAM198B,ZIC4,SCML2,EFEMP1,FCGRT,FER,FGF1,OLFM1,FGFR1,POLK,HPCAL4,FOXG1,SYNCRIP,IQCG,NBEA,CAMKK2,ATP6V1H,CELF1,AP4B1,NRG3,GAB1,HRASLS5,CHL1,GABRG1,SIGLEC8,GBX2,DBF4,ZNF638,INSM2,GNG4,LNX1,PRUNE2,ATF7,EML4,RAPGEF4,ATP2B1-AS1,GRIA4,GRIK2,BTN2A1,GSTM5,PSIP1,MAEL,NXPH3,HMGB1,GABARAPL2,ZNF491,DHX35,C2orf72,HES5,ITPKB,JAK2,KCNC1,KCNK1,KIF2A,KTN1,HECTD2,MEIS1,AFDN,XRRA1,MOBP,BLOC1S2,ADAM22,CTNNA3,NCAM1,ZC3H12B,NEFM,CCDC13,LRIT2,NRGN,NTRK2,OPCML,OPHN1,ZDHHC22,KCNK10,PBX1,DPY19L2P2,PDE3B,SERPINE2,SEMA5B,PIK3CD,ZNF655,SNX10,XRN1,KCTD15,GPSM2,PMP22,PPP2R5E,RANBP3L,MAPK9,KLK6,BCAS3,LRRC49,MDGA2,ELOVL2,PTPN13,C1orf109,ZSCAN2,OXR1,BSDC1,RDX,REV3L,PRRT2,RIC8B,PBRM1,RNASEL,CCDC82,ZNF532,ROBO1,RORB,RPL15,UEVLD,MCMBP,ACER3,TCP11L1,ABCA11P,ATAT1,SALL1,ATXN2,FNIP1,SEC14L1,NLGN4Y,ITSN1,FAM102A,CHD9,SLA,ZNF365,SLC1A3,FAM81A,KANSL3,SNRPN,TNIK,ZCCHC24,ZSWIM8,SPP1,ZC3H13,KIF1B,SSTR2,EPB41L3,ZSCAN29,DIP2A,AJAP1,RHBDL3,VPS13A,PLCB1,SYPL1,CAMTA1,DNMBP,KLHL4,TCEA1,SATB2,CUX2,TPCN2,RPGRIP1L,DOCK9,ARHGEF12,HIF3A,DICER1,DICER1-AS1,ZFPM2,C18orf54,HHIP,THRA,GZF1,RIMBP2,KCTD2,R3HDM1,ZNF384,TRIO,AMACR,TSC1,ANO5,PLEKHH2,VLDLR,LMF1,ZNF781,XRCC4,PCDH20,ZIC3,MICU3,KCNT2,FMN2,LYPD6,SH3GLB2,PLPPR5,DHX33,CA10,EMSY,NT5M,GDPD5,STOX2,EPM2A,FAM13C,MARCH8,HNRNPA3,PHTF2,JMJD1C,VANGL2,CBLN2,CPNE4" MicroRNA hsa-miR-1324:mirSVR_highEffct hsa-miR-1324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-110 1.54E-106 2.01E-109 1.85E-108 283 1178 "SDE2,ACLY,NCKAP5,ACTN2,SLITRK1,ADD3,PLEKHH1,KIAA1211,NLGN4X,CC2D2A,SMIM17,ALCAM,ARHGAP20,AMPH,ZFAT,CNIH2,APAF1,APBB1,MAGEE2,ALS2,NT5C3B,FAM131A,MIER1,PPP4R4,ASPH,ZSCAN18,DDX3Y,ATP1B3,DPY19L3,DST,ST3GAL5,SCAPER,OSGIN2,CALB1,CALM1,VSTM2A,RUNX1T1,CBR1,CERS5,CDC42,CDH10,L3MBTL4,MAGI1,CHGA,MS4A7,SYNPR,TAOK2,IGFBP7-AS1,COL11A2,SLC4A8,ZFP28,MFSD4A,HS3ST5,OSBPL3,UBXN2A,ST18,USP6NL,CCDC144A,GPRASP1,MYADM,PITPNC1,C8orf34,SNAP91,RABGAP1L,TMCC2,FAM107B,DNM1,USP3,DNAH9,CPEB2,DSCAM,FARSB,GOLT1B,EBF1,EDN1,PHC2,HIPK3,FCF1,FAM13A,EGFR,PLEKHA1,VPS13B,EPHB1,GPHN,EPS8,ZNF549,SPEG,DUSP27,WAC,ST3GAL6,KAT8,SEC24B,FGF13,MAD2L2,FHL1,SUCO,ATP13A4,NOP56,SYT3,EFCAB2,TMEM107,SPECC1,KHDRBS3,CSPG5,SARAF,AP4B1,MEGF11,GABRA1,GABRA2,GAD1,BRPF3,ARPP21,NCKAP1,MTHFD2,DISC1,GGT7,RUNDC3A,GK,GLYR1,MSL3,PCDH11X,ZNF638,FERMT2,GPM6B,CCDC184,B4GALNT4,EML4,STMN2,GRIA2,DIDO1,NR3C1,GRM8,FAM19A2,PTPN5,KAT7,ZBTB49,MFSD2A,CELF3,TOX2,HRH3,HLF,HSF2,MSL1,DOCK7,IGSF1,IL11RA,BRINP3,KLRC2,IPO5,MAPT,MARK1,LDLRAD3,SHC3,NRBP2,MTR,NAP1L1,NASP,CCDC13,NPY,HCN1,IGSF11,OPRL1,CLDN11,ZNF827,PCDH8,PCMT1,PDE2A,PDE3B,ENPP2,PFKFB3,SERPINE2,NALCN,PIK3CD,PLCL1,PMP22,MAPKAP1,LRP12,MAGEL2,NXPH1,TATDN3,PPP3CA,PPP3CB,PRKACB,EPDR1,HYDIN,CNNM2,SLC22A23,GDPD2,PTHLH,TMEM260,PTPRE,QDPR,PID1,PLEKHB2,ZNF493,RDX,TRIM68,REV3L,MORC4,GTDC1,FIGN,RFX4,SEC61A2,SLC25A36,RNASEL,SETD5,CARF,ROBO2,SGSM1,KCNIP1,NCBP3,SARS,LRRTM4,COPZ1,SGK1,KIF21A,ITSN1,WDR47,NAPB,SLCO1A2,CDK5RAP2,INTS9,SNCB,SNRPN,MYT1L,TNIK,SP4,ZNF423,NPAS3,SPART,TAB2,ELOVL4,ZFR2,VAMP1,PLCB1,SYP,SYT1,COBL,MTCL1,PJA1,TBCEL,ZEB1,PCDHB7,CRB1,HHIP,TIAM1,DDHD1,METTL3,PRMT8,TRIO,ANKRD20A2,SSBP2,TTC3,UCHL1,SLAIN1,PITPNB,CCDC14,BEST1,NSD2,XRCC4,ZIC3,ZNF711,ZNF24,NDRG4,CELF4,FSTL5,ZSCAN26,ANKS1B,FTSJ1,EMSY,STOX2,SCG2,NAV3,KCNAB1,SLC17A6,KAT6A,PHTF2,FBXO36,JMJD1C,NLRP3,RNF170,SNX14,GAN" MicroRNA hsa-miR-4294:mirSVR_lowEffct hsa-miR-4294:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.88E-110 1.62E-106 2.11E-109 1.94E-108 307 1380 "ACADM,CLK4,AS3MT,SYS1,XKR4,ADD1,LRFN2,KIDINS220,BEND6,KIAA1324,TAOK1,ALCAM,UNC79,AMT,ZFAT,CDC42BPA,PPFIA1,PKP4,GPAM,CACHD1,AQP4,CDK10,LINC00173,CAPRIN2,ASPH,DACT3,PCDHGB4,TMEM108,ATP1A2,B3GALT2,ADAM23,ADAM15,BACH1,MIR9-3HG,CFLAR,SYNJ2,CASTOR3,CA4,CA12,CACNA2D1,CACNB2,KALRN,SPAG9,RUNX1T1,CCPG1,PLEKHB1,EPS15L1,SRP14-AS1,MAP4K4,LY86,CNGA3,TBPL1,AHCTF1,SMARCAL1,TOGARAM2,MYRIP,SLC35F1,ENTPD4,NCOR2,CLIP3,ABCG1,SNCAIP,SEC24C,CSNK1E,ATRNL1,VCAN,FAM169A,PITPNM3,PHF14,CFAP61,NRSN1,RUBCN,MYADM,PHF19,RIMS3,ARMCX2,DNAJC6,DGCR5,ZBTB24,SV2A,SRGAP3,SGSM2,NYAP1,RPS6KL1,GOLT1B,E2F5,EDNRB,SYT15,HEYL,KLHL5,FRY,CACNG7,CELSR3,EGFR,IRAK4,RGS17,BSCL2,TUBD1,EPB41,MFSD10,LRRC23,RASGRP2,DENND4A,ZNF549,CDKL3,TOMM40L,FCGRT,ZSCAN30,FER,FGF12,FGFR1,POLK,UBE2E3,SEMA4D,NOP56,ZCCHC17,FAM49B,CAMKK2,DACH2,DOT1L,SDCBP2,ZNF44,GALNT15,DENND2A,ZNF234,SULT1C4,CSDC2,GHR,CRCP,GLYR1,GNAS,GPR12,NR3C1,MFSD2A,ARHGAP19,LINC01102,HMGCR,AGBL5,SHISA6,SMAP1,LRRC25,INPP5B,ITGAM,KCNB1,KCNF1,KCNJ16,KCNMA1,GATD1,KIF5C,LIMS1,MAN2A2,MAT2A,AQP11,MDM4,MEST,KCTD6,MN1,CD200,MPP2,BCO1,MXI1,MYBPC1,MYL3,NDP,NOVA1,DNHD1,OGG1,OLR1,P2RX7,PCDHGC3,PDCD2,PDE1A,PIRT,PDGFRA,ENPP2,PFKFB2,ZNF655,ZFYVE21,JAKMIP1,FTO,SLC25A23,ZNF426,ANKRD16,EPB41L4B,POLG,POU6F1,PPP2R5C,PRKCG,GRAMD1C,UHRF1BP1,PTPN13,PTPRE,C1orf109,ACSM5,TUG1,ZNF793,RALGDS,NWD1,VEPH1,TRIM68,RLBP1,NUDT11,ALG9,GSTCD,MCMBP,DGLUCY,MAPK12,SEMA6D,SCN2B,SCP2,SEC14L1,TRIM46,GALNT10,SH3GL3,FERMT1,AMBRA1,ST3GAL3,DZIP1,ZNF365,SLC1A7,RUFY2,FAM214B,RAB3GAP1,BTBD7,MAST1,CDK5RAP2,SMARCD3,MBD5,SNRPN,SOX1,ZSWIM8,KDM4C,PEG10,ARHGAP26,NFASC,NKAIN2,KLHL7,FGD4,NUDT10,C3orf70,PLCB1,TAC1,POPDC3,KAZN,ATMIN,ACSL6,DMXL2,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,GPRIN3,FRYL,CYB561A3,RNF216P1,MTMR14,TMEM9,TLL2,ZFP91,SEZ6L,TPM4,TRH,TRO,PPIL6,TSN,TSC1,TTTY15,TUBB1,HEPACAM,RPL7L1,SLAIN1,FLRT2,BEST1,CLDND1,RICTOR,ZNF708,ZNF24,CFAP52,MKRN3,LYPD6,DPYSL5,ANKS1B,STMN4,SCG2,PCDH15,SLC17A7,TRIM16L,PCBP4,MPPE1,UBE3B,FBXO36,CAMK1G,NLRP3,VANGL2,NETO1,RNF146,FAM198A" MicroRNA hsa-miR-4300:mirSVR_lowEffct hsa-miR-4300:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.90E-110 1.63E-106 2.11E-109 1.95E-108 293 1261 "VWA5B2,ASIC1,ACHE,NBAT1,SYS1,ACTN1,GPRIN1,KLHL32,SLITRK1,ADCY6,SLC12A5,SORCS1,GRAMD1B,PTCHD1,AP2A2,AP1B1,C1QTNF1,PCDH10,ZFAT,OGT,USP28,KCNAB2,MIER1,SLC7A14,SFMBT2,SEMA4G,PRX,PCDHGB4,ADAM15,ADGRB1,LINC00847,BBS2,BCL2L2,KSR1,CASTOR3,AP1M1,CFAP410,CA8,CACNA1D,CACNG1,LURAP1,CALB2,HAP1,BRSK2,ISPD,CD86,CBFA2T2,DGKI,SRSF11,CHRM1,PLEKHB1,CASC2,B4GALT6,TAOK2,PPT2,FBXO7,MAP4K4,ARMC8,CABP1,MFSD4A,CHD1L,ANKRD44,CS,SNCAIP,CSF1R,NCAN,PLXNA4,KATNAL2,HDAC4,PHF19,DGKB,DGKG,ZNF804A,DLG2,DOCK2,SLC12A6,SIDT2,CACNG7,RBM12,ABI2,SORBS3,COPS4,C3orf18,EN2,VPS13B,EPB41,EPB41L1,EPB41L2,COQ7,EPHB1,RASL12,SIRPB1,CD320,PTK2B,KAT8,SPSB4,POLK,SUCO,FOXM1,ANKFY1,SORBS1,AK8,PDLIM5,USP21,CELF1,CGREF1,NSG1,STAU2,AP4B1,ABLIM2,ZNF512,GAB1,ARPP21,GHDC,CPLX2,GCK,ALDH1L1,SRCAP,TTBK1,RAB30,KDM2B,POLL,LUZP2,GPD1,GPD2,GPM6A,FUT10,GPR12,ATP2B1-AS1,GRB10,GRIA2,BTN2A1,PTPN5,GSTM5,KAT7,GSTT2,FAM107A,ATOH8,ZHX1,PTGDR2,ATXN2L,ARHGAP36,ZDHHC15,HSD17B1,SHISA6,LRRC25,ZNF385B,KCNA6,KCNJ5,CREG2,KLRC2,TTYH2,VWA5A,MAN2A2,DBNL,SAMD5,MYT1,NBL1,NELL1,NFE2L2,NNAT,NOVA1,SMIM11A,PCDHGC3,PIRT,NLGN3,FAM216A,PLCB2,ST8SIA5,PLIN1,FXYD1,PLXNB3,PRIMPOL,ANKRD16,EPB41L4B,C19orf57,NKAIN4,PRKCZ,WBP1L,PXK,TMEM260,STK32A,FAM120C,SLC25A48,PLEKHB2,ZNF793,SUSD4,RDX,GAL3ST4,RGS4,RPRD1A,MYH14,YY1AP1,SNX22,KIAA0895L,LRRK2,ATAT1,FAM182A,CSRNP3,LRRTM4,PRCD,ASIC4,SOX6,TRIM46,CASC3,NTNG1,SYBU,ST3GAL3,CTXN2,ST8SIA1,SLA,SLC1A3,RPH3A,SLC6A7,SLC8A2,SIRT2,SMARCC2,MAPKBP1,SNCA,MBD5,SNRPN,WDTC1,BDP1,TSNAXIP1,SOX10,SP2,CLUAP1,KDM4C,IDI2-AS1,PEG10,CDK19,LMO3,ZSCAN29,APOM,RHBDL3,ARHGEF9,SYN1,FBXW11,VWA3A,NEU4,TCF7,TCF7L2,ZEB1,TPCN2,USP22,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,NAT16,PCDHGA1,SIK3,RNF216P1,ATP13A2,DICER1-AS1,TIAM1,TIE1,TMEM9,TLL2,ERCC6L2,FAM124A,PIK3R5,IL34,WBP2,TRPM2,TSC1,SLC35A4,OSBP2,FLRT1,TBC1D15,CLIP2,KLC2,ZNF70,LYPD6,TMEM198,DNALI1,SLC38A1,URM1,FBXO36,RNF170,NETO1,AP3B2,LAS1L,FAM198A" MicroRNA hsa-miR-501-5p:mirSVR_highEffct hsa-miR-501-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.09E-110 1.73E-106 2.25E-109 2.07E-108 311 1415 "ACADM,CLK4,PLEKHH1,PWWP2A,RNF150,BEND6,SLC24A4,AP2A2,HACE1,C1QTNF3,PPFIA1,PKP4,APBA2,EPB41L5,ALS2,CACHD1,AMER3,SHTN1,MIER1,CADPS,MARK4,CAPRIN2,ASPH,NCOA1,B3GALT2,NOL4,BACH1,CFLAR,SYNJ2,FUBP1,CACNA1A,CACNB2,LURAP1,PTBP2,CAST,RUNX1T1,MTMR7,INA,DGKI,CDC27,DCLK1,ZMYM4,LGI1,MAGI1,CFL2,CHN1,MS4A7,B4GALT6,IGFBP7-AS1,ZFYVE9,CLCN3,QKI,CNTN1,IQCK,AKAP6,SLC4A7,MYRIP,PREPL,CREM,NCOR1,CS,SLITRK5,UBXN2A,CFAP61,NRSN1,RIMS2,EDRF1,KIAA0586,DCC,YTHDC1,DNAJC6,C8orf34,ZEB2,MAGI2,DDX46,SACS,NTM,ZNF582-AS1,DLG2,PDCD6IP,DYRK1A,DNM1L,EDN3,FCF1,CACNG7,RBM12,GPR61,PHF20L1,MBNL2,ELAVL4,PCOLCE2,PAN3,LRRC17,CLVS1,FAM198B,FABP7,FCGR1A,CEP78,GORAB,POLK,FLT1,C2orf88,ZBED3,ATP6V1H,KHDRBS3,CELF1,TVP23A,GABRA3,GABRB1,GALNT15,DENND2A,BRPF3,GAP43,MTHFD2,KIAA1841,TUBGCP4,PCDH17,MALT1,GLI2,PCDH11X,ZNF638,GPM6B,TDRKH,STON1,GRIA2,GRIA4,GRIK1,GRIK2,NR3C1,GRM1,RNF165,LINC01551,PSIP1,MAEL,RASSF8,HAS2,UBE2QL1,VSIG4,HPSE2,IGFBPL1,HSD17B1,SMAP1,HTR2A,IDH3A,DOCK7,LRRTM3,KCND2,KCNH2,KCNK1,KCNN2,KIF2A,KIT,KLC1,KTN1,MAN2A2,MAP4,MARK1,MBD1,MBNL1,LRP1B,MEIS1,SRSF12,AFDN,MN1,BLOC1S2,RSPO2,NEXMIF,ZNF862,NAP1L1,P2RY13,NDP,NFE2L2,NINJ2,CNOT4,HCN1,NTRK2,NTRK3,TBC1D25,GLIPR1L2,PBX1,PDE4B,PDE4D,NALCN,CCSER2,SNX10,XRN1,KCTD15,PLIN1,SMOX,PLP1,HMGCLL1,PLXNB1,PURG,PNMA3,ANKRD16,PMP2,PMS2,ING3,SPATA6,NXPH1,DRAM2,PPP3CB,PRKCZ,GON4L,CNTLN,ANKHD1,MTMR10,EML5,PTPRG,TMEM145,ZNF844,CEP97,FAM66C,SLC25A41,RAP1GDS1,RDX,RET,RFX3,RFX5,SEC61A2,EXD2,ROBO2,PCMTD2,TMEM100,BAALC,ATP8B4,GLDN,LRRK2,LGR4,STX1B,FAM192A,SATB1,SCN3A,TNFRSF19,SEC14L1,TRA2B,HSPA4L,NLGN4Y,SGK1,KIF21A,ASAP3,ST6GAL1,SLC1A3,RUFY2,FAM214B,SEPHS1,ARHGEF40,ATF7IP,TET1,NAXD,SORCS3,SMARCD3,RCOR3,ANKRD36,SNRPN,UNC80,BDP1,ENKUR,PEG10,ZBTB43,COLGALT2,RGL1,DIP2A,ADHFE1,STXBP1,KLHL7,FGD4,ZC3H4,VPS13A,SYT1,TAC3,KAZN,CAMTA1,CAMSAP2,FAM208A,CUX2,RPGRIP1L,SYNE1,SIK3,PMS2CL,AP4E1,TJP1,ERCC6L2,NPL,RGMB,AMACR,RFTN2,RPL7L1,UBE3A,UGT8,VAV1,TOM1L2,TBC1D15,XPO1,ZNF24,KCNT2,GPR158-AS1,LYPD6,SLC30A4,PRDM2,PARP6,PRDM10,RNF103,TMEM178A,WIPF2,FAM13C,NUP214,JMJD1C,KLHDC1,FRMD6,GAN" MicroRNA hsa-miR-424:PITA hsa-miR-424:PITA_TOP PITA 3.54E-110 1.99E-106 2.57E-109 2.37E-108 227 754 "SLITRK1,GALNT13,AXIN2,USP31,ADRB2,AP2A1,LRRC7,ARHGAP20,MARCH4,OGT,CNIH2,CNTNAP1,APP,AQP4,ARHGAP5,STK33,ZBTB10,DDX3Y,SLC4A4,ATP2B2,BCL2L2,BCL7A,DCAF5,CDK5R1,SYNJ1,FUBP1,LDLRAD4,BTRC,CACNA1E,CAMK2G,MAP7,RUNX1T1,DCLK1,SRSF11,SOCS6,KMT2C,CLCN3,CLCN4,QKI,SLC4A7,TBPL1,CLOCK,NCOR2,AATK,LRIG1,OSBPL3,SOCS5,ERC2,RUBCN,USP6NL,DOCK4,MYADM,PHF19,KCTD8,IST1,IP6K1,CTIF,YTHDC1,MYEF2,SPOCK3,USP3,DYNC1I1,CPEB2,DMTF1,PDCD6IP,ARRDC4,GOLT1B,ST8SIA3,TSPAN5,SEMA3D,SIDT2,RBM12,PHF20L1,MBNL2,EGR3,PLEKHA1,DCTN4,EN2,EPB41L1,ANKRD13B,ETV1,EYA1,EZH1,ACSL4,CAMSAP1,SUCO,AGAP2,AGAP3,SYT3,ARFGAP2,CSPG5,TPPP3,CAB39,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,IL1RAPL1,WIF1,HAS2,ZHX1,BACH2,ACOT7,C5orf24,SLC35G1,KCNC2,KIF5A,KIF5C,KLC1,ARHGAP12,MAN2A2,AQP11,CHIC1,LRP1B,GIT1,MYO5A,NEXMIF,PABPC1L2A,ZC3H12B,HCN1,ODF2,OMG,PCDH9,PCMT1,PDE3B,CAMKV,PIK3R1,RETREG2,EPB41L4B,FAT3,NXPH1,POU3F2,MED1,MINDY2,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK9,RELN,CNNM2,SNRK,PTCH1,PTPRD,FAM120C,PEX5,PID1,TMEM255A,RBBP6,BSDC1,ZFHX4,ZNF532,TMEM100,FBXW7,SYNDIG1,SALL1,SEMA6D,ATXN2,SCN2A,SCN3A,SCN4B,SCN8A,ELMOD1,HSPA4L,PUF60,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,FNDC3A,NLGN1,DZIP1,SLC1A2,FAM81A,WDR47,SLC12A2,SLC20A2,RCOR3,SNAP25,TMCC1,FAM219A,SON,WDTC1,MYT1L,ZHX3,LHFPL4,TSPYL2,STX1A,GSE1,PRRC2C,VAMP1,ARHGEF9,SYN2,SYPL1,SYT4,WWC1,SATB2,TRIM2,SYNE1,FRYL,AHCYL2,DICER1,TGFBR3,SLC44A1,HEY2,CSMD1,NR2C2,TRPC1,CADM1,AMOT,NSD2,WNT7A,KLC2,ZIC1,CSDE1,EVI5,STOX2,TUBA1A,KCNAB1,PAK5,ADAMTSL3,PIANP" MicroRNA hsa-miR-491-3p:mirSVR_highEffct hsa-miR-491-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.67E-110 2.62E-106 3.39E-109 3.12E-108 286 1205 "FMNL2,CCDC85A,ADD2,ADD3,PWWP2A,PTCHD1,HECW2,OSBPL1A,WDR35,C1QTNF3,LRRC7,ALAD,SMIM17,SEMA6A,ALCAM,PCDH10,FAM135A,ANK3,PARG,APBA2,ALS2,LGR5,ARHGAP5,LINC00173,ASPH,NCOA1,NUMB,B3GALT2,ZNF599,BMP7,DST,ARHGEF7,BTK,SCAPER,MTMR2,CABP7,THSD7A,CALM1,KALRN,NFS1,CBR1,CBFA2T2,TMEM257,LRBA,ZMYM4,SRSF11,CHM,SYNPR,KMT2C,RAB33A,CLU,NIPBL,ARHGEF6,CHD1L,SH2B1,SEC24C,SOCS5,ERC2,APPL1,PHF14,CYBB,DOCK4,FGFR1OP2,ARHGAP24,DGKB,SPOCK2,PABPC5,PLEKHM1,MYEF2,MAGI2,ALKBH8,RHOBTB1,PLPPR4,SNAP91,DLG2,DMD,USP3,DYNC1I1,CPEB2,ABI1,PDCD6IP,ECM2,DYRK1A,ABCC9,GOLT1B,SEMA3D,RBM12,PHF20L1,EGFR,KMT5B,ASB3,EIF4G2,ELAVL2,PLEKHA1,EPS8,NRN1,ARMCX1,FABP7,PTK2B,ZNF589,SLC9B2,KIAA1109,POLR1B,FOXO3,FLT1,ANKFY1,STAMBP,ATP6V1H,ST6GALNAC3,AP4B1,GABRA1,GABRB1,GABRB3,ADAM28,GHR,PPARGC1A,GK,COPS8,HPGDS,PCDH11X,LUZP2,GPM6B,RAPGEF4,GRIA1,GRIA4,GRIK3,PRDM5,GRM7,FAM19A2,FAM107A,MAP4K5,HNMT,ZDHHC15,IDH3A,LRRCC1,SCIN,LRRTM3,KCNA2,KCNC2,KLRC2,KLC1,HECTD2,NCOA7,MARK1,LYPLAL1,AQP11,MATN2,MEST,KCTD6,AFDN,MOBP,MRPL42,SCG3,NAP1L2,NF1,NOVA1,OLR1,CLDN11,PCDH9,PRTG,PDGFRA,PENK,ABCB1,XRN1,PLIN1,HMGCLL1,STRN3,LRP12,POU3F2,KANSL1,PKN2,HYDIN,SAMD9,MTMR10,PTHLH,TMEM260,PTX3,PEX2,TMEM255A,FAM184A,ZDHHC14,RDX,SLC6A15,ZYG11B,RGS3,ZFHX4,ZNF532,GSTCD,PCMTD2,RPE65,RPL15,FBXW7,TCP11L1,LRRK2,CLIP1,RTN1,ZNF568,MIR124-2HG,FNIP1,SLC30A10,SOX6,FNDC3A,FHOD3,SLITRK3,CNKSR2,SYBU,CTXN2,SEC31A,SLA,SLC1A3,FAM81A,PPP4R3A,EPN2,RUFY2,LRRC55,CPEB4,SORCS3,SMARCE1,ANKRD36,RIMS1,SNRPN,UNC80,MYT1L,EMC1,HECW1,UHRF1BP1L,KIF1B,CDK19,RBM26,C11orf87,TROVE2,LARP4,ERBIN,ZSCAN29,ELOVL4,SEPT8,RGL1,NSFL1C,NECAB1,SYT11,JMJD6,PRRC2C,PLCB1,TACC1,MTCL1,VWA3A,ZFP90,WASHC4,WDR7,PCDHB7,PCDHB6,PUM2,USP32P1,TEX15,SIK3,TEK,FAM200B,SIRT1,TGFBR3,HHIP,SLC44A1,GZF1,HEY1,ERCC6L2,BEX4,RIMBP2,RBFOX2,TPM3,TRIO,TRPC1,TUBB1,SLC35A4,PLEKHH2,USP1,FMN2,ZNF138,ZNF154,FSTL5,WNK1,FAM47E,SLC17A6,PLSCR4,GOPC,ADAMTSL3,MSRB3,KLHDC1" MicroRNA hsa-miR-320b:mirSVR_highEffct hsa-miR-320b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-109 5.73E-106 7.39E-109 6.81E-108 311 1421 "ABCF1,KCNH8,SYN3,NCKAP5,ERMN,SLC44A5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,SPOP,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,SHTN1,MIER1,CDK13,ASPH,ZBTB10,TMEM108,NOL4,DPY19L3,SNAI3-AS1,CFLAR,KSR1,ARHGEF7,CA8,CACNA1E,PTBP2,SLC25A14,VXN,SPAG9,MAP7,CBLN1,CBR1,LDB2,CCNH,MTMR7,INA,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CX3CR1,CCDC144A,HDAC9,GPRASP1,FRMPD4,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,GNE,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,EFS,CDKL3,ADGRV1,EYA1,NRN1,WAC,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,CAP2,ANKFY1,COQ5,TACC2,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,NRG3,ZMAT1,STAG2,GABRB1,CAB39,ZMYND11,B4GALNT1,SYT17,C15orf41,DISC1,DNER,ARFIP1,BRD8,DBF4,GLYR1,MAP7D2,INSM2,LOXL3,PCLO,GRIA4,BVES,MAEL,HAS2,ARHGAP36,VSIG4,HMGB1,GABARAPL2,AGBL5,SMAP1,MSL1,SOWAHA,IGSF1,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,SESN3,ADAM22,CTNNA3,MXI1,NELL2,NF1,CNOT4,GPR88,PBX1,PCDH9,PCSK2,PDE3A,PDE3B,CYTL1,HMGCLL1,RC3H2,PRRX1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,PPP3CB,PRKCG,MAPK9,GRAMD1C,APTX,MDGA2,CNTLN,PLPPR1,PTPRG,TMEM255A,FAM66C,SH3TC2,RBBP6,VEPH1,ZDHHC14,RFX4,RGS10,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,TMEM100,RPL15,ZC3H14,ZNF671,ADAL,WLS,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SELL,SUPT20H,HSPA4L,ITSN1,FERMT1,ASAP3,HKDC1,MAGI3,FBXO11,FNDC3A,SLITRK3,CNKSR2,WDR47,SLC6A8,CPEB4,SORCS3,CDK5RAP2,LIMCH1,CMTR2,PALLD,SON,WDTC1,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,TAC1,ATP11A,CAMSAP2,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,WASHC4,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,ZFP91,TMOD1,KAT6B,TPD52L2,TPM1,TPM3,PRMT8,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,AMOT,FRRS1L,PITPNB,VLDLR,GUSBP1,XPO1,XRCC4,ZIC3,ANKS1B,EMSY,PRTFDC1,PRDM10,SLC17A6,GOPC,ST7,PAK5,HNRNPA3,PHTF2,NLRP3,SSPN" MicroRNA hsa-miR-320a:mirSVR_highEffct hsa-miR-320a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.02E-109 5.73E-106 7.39E-109 6.81E-108 311 1421 "ABCF1,KCNH8,SYN3,NCKAP5,ERMN,SLC44A5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,SPOP,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,SHTN1,MIER1,CDK13,ASPH,ZBTB10,TMEM108,NOL4,DPY19L3,SNAI3-AS1,CFLAR,KSR1,ARHGEF7,CA8,CACNA1E,PTBP2,SLC25A14,VXN,SPAG9,MAP7,CBLN1,CBR1,LDB2,CCNH,MTMR7,INA,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CX3CR1,CCDC144A,HDAC9,GPRASP1,FRMPD4,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,GNE,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,EFS,CDKL3,ADGRV1,EYA1,NRN1,WAC,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,CAP2,ANKFY1,COQ5,TACC2,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,NRG3,ZMAT1,STAG2,GABRB1,CAB39,ZMYND11,B4GALNT1,SYT17,C15orf41,DISC1,DNER,ARFIP1,BRD8,DBF4,GLYR1,MAP7D2,INSM2,LOXL3,PCLO,GRIA4,BVES,MAEL,HAS2,ARHGAP36,VSIG4,HMGB1,GABARAPL2,AGBL5,SMAP1,MSL1,SOWAHA,IGSF1,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,SESN3,ADAM22,CTNNA3,MXI1,NELL2,NF1,CNOT4,GPR88,PBX1,PCDH9,PCSK2,PDE3A,PDE3B,CYTL1,HMGCLL1,RC3H2,PRRX1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,PPP3CB,PRKCG,MAPK9,GRAMD1C,APTX,MDGA2,CNTLN,PLPPR1,PTPRG,TMEM255A,FAM66C,SH3TC2,RBBP6,VEPH1,ZDHHC14,RFX4,RGS10,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,TMEM100,RPL15,ZC3H14,ZNF671,ADAL,WLS,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SELL,SUPT20H,HSPA4L,ITSN1,FERMT1,ASAP3,HKDC1,MAGI3,FBXO11,FNDC3A,SLITRK3,CNKSR2,WDR47,SLC6A8,CPEB4,SORCS3,CDK5RAP2,LIMCH1,CMTR2,PALLD,SON,WDTC1,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,TAC1,ATP11A,CAMSAP2,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,WASHC4,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,ZFP91,TMOD1,KAT6B,TPD52L2,TPM1,TPM3,PRMT8,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,AMOT,FRRS1L,PITPNB,VLDLR,GUSBP1,XPO1,XRCC4,ZIC3,ANKS1B,EMSY,PRTFDC1,PRDM10,SLC17A6,GOPC,ST7,PAK5,HNRNPA3,PHTF2,NLRP3,SSPN" MicroRNA hsa-miR-106a:PITA hsa-miR-106a:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-17:PITA hsa-miR-17:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-20b:PITA hsa-miR-20b:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-93:PITA hsa-miR-93:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-106b:PITA hsa-miR-106b:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-20a:PITA hsa-miR-20a:PITA_TOP PITA 1.11E-109 6.21E-106 7.95E-109 7.33E-108 233 800 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,XRN1,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-487a:mirSVR_highEffct hsa-miR-487a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-109 7.86E-106 1.01E-108 9.26E-108 263 1025 "CLK4,NCKAP5,ACTN1,CSMD3,SLC12A5,PWWP2A,AP2A2,HECW2,AGT,NME5,OSBPL6,LRRC7,ARHGAP20,CDC42BPA,FGD2,PPFIA2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,PPP4R4,TMEM263,RGS20,STK33,NUMB,RASL11B,ASTN1,SLC4A4,SEC11C,CFLAR,CACNB2,CALB2,PTBP2,CCK,LDB2,REPS2,ZMYM4,LGI1,MAGI1,RCBTB2,SRSF11,NGEF,ABCG2,TMEM184B,SULT4A1,CNR1,SLC25A27,COL9A1,CRHBP,GDA,TRIM69,ATRNL1,SLITRK5,APPL1,DOCK4,GAPVD1,FRMPD4,TOX,LIN54,KIAA0586,DAPK1,YTHDC1,C8orf34,ZEB2,ZBTB24,MYEF2,MAGI2,ZC3H11A,SMG7,PLPPR4,SGSM2,USP3,CPEB2,CASP8AP2,DRD1,PDCD6IP,DTNA,DYRK1A,DNM1L,GOLT1B,HIPK3,FAM13A,PHF20L1,MRO,ELAVL2,EML1,GPHN,SRRM1,MRPL10,SIRPB1,ABCA8,TAOK3,CEP78,GORAB,CAMSAP1,SUCO,MEX3B,VTI1B,NPTN,ARFGAP2,GAD2,GALC,GAP43,NEU3,TUBA8,PPARGC1A,COPS8,ZNF638,LNX1,GPD2,GPM6A,TDRKH,GRIA4,MFSD2A,PSIP1,C1orf94,HNMT,SMAP1,ZIC5,LRRCC1,IGSF1,INSM1,KCNC1,KCNMA1,KCNN2,KIT,HECTD2,MARK3,MEIS1,MEST,AFDN,MRPL42,NELL2,NF1,HCN1,OPHN1,LOC100128398,CLDN11,ETFRF1,PDE4D,SNX10,KCTD15,ST8SIA5,EPN1,PDZRN4,SPATA6,EPB41L4B,DRAM2,PPM1B,PPP2R5E,PPP3CB,PRKACB,PKIA,PRPSAP2,DCHS2,SNRK,MTMR10,PTPN13,EML5,PTPRZ1,MARCH1,CEP97,OXR1,RASGRF2,RBBP6,ZDHHC14,RDX,MORC4,RFX3,RFX5,SEC61A2,RNF220,TMLHE,CARF,PCMTD2,ZC3H14,LGR4,HUNK,WLS,ZNF568,AP1AR,ATXN2,ITSN1,MAGI3,FNDC3A,WDR37,FAM81A,RPH3A,YPEL4,RAB3GAP1,CCDC88A,SLC9A5,ANKRD36,LIMCH1,MBD5,SNRPN,SON,PDZD2,SOX5,KIF21B,CDK19,MCF2L2,NPAS3,ERBIN,ZSCAN29,NEK4,SEPT8,NSFL1C,NECAB1,SYNE2,ARHGEF9,VPS13A,NUDT10,SYPL1,COBL,SYT4,TAC1,MTCL1,PJA1,MLST8,TAF9,ADGRL3,ZEB1,RPGRIP1L,PUM2,SIRT1,ITGB3BP,AP4E1,AKTIP,C5orf64,TP53BP1,CDK20,RUNDC3B,STXBP4,TRPC1,TRPC3,RUSC1,KCNE5,ANO5,RFTN2,TMEFF2,SGK3,UGT8,ZFP37,ZNF711,ZNF19,ZNF32,KCNT2,FSTL5,EML6,ANKS1B,SMARCAD1,SLC30A4,EVI5,TMEM178A,PCDH15,TRIM16L,GOPC,FAM13C,PHTF2,JMJD1C,ZNF248,SSPN" MicroRNA hsa-miR-3199:mirSVR_lowEffct hsa-miR-3199:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.44E-109 8.07E-106 1.03E-108 9.49E-108 310 1414 "SYS1,PLEKHG5,ADCY6,RNF157,ADD1,ADD3,SORCS1,ERMN,PLEKHH1,ADORA2A,MTA3,SNX32,PCDH19,LRRC7,UNC79,AMPD3,LRFN1,ZFAT,EP400,PPFIA4,PKP4,VAT1L,PPFIA3,MIER1,SFMBT2,SEMA4G,IGDCC4,PDE8B,ATP1A3,ADAM15,CFLAR,KSR1,GPC2,OSGIN2,CDK5R2,CA4,CACNA1D,CACNA1E,PTBP2,NGB,SPAG9,P2RX6,ARHGEF1,SYNGR3,ENTPD6,DGKI,CD81,NOG,NPIPA1,ASIC3,CHN2,CHRM1,PLEKHB1,PPT2,COG1,TPP1,TMEM59L,DNAJB5,IQCK,WHRN,SUMF2,IGDCC3,RBM39,CRMP1,CRY2,ANKRD44,CRYM,CS,TENM4,VCAN,PDE4DIP,SDC3,ERC2,RUBCN,BOC,KATNAL2,SNPH,ZFYVE16,DAPK1,SCRN1,AIF1L,DNAL1,ZBTB24,DDX46,SMG7,SGSM2,FAM107B,DLG2,EXOG,DRP2,DTNA,AASDH,CNNM1,HEYL,TMTC1,GPR61,TNK2,MRNIP,ELN,DCTN4,EMX2,CDHR1,RTN3,CEND1,ABCA8,TUBB4A,TAOK3,CEP78,SPSB4,CAMSAP1,HPCAL4,IP6K2,TMEM175,ERGIC3,KHDRBS3,B3GAT1,NRG3,ABLIM2,TVP23A,MEGF11,GABRG1,BRPF3,NCKAP1,DISC1,GPR162,GFER,AIFM3,LOXL3,GNAS,WDFY3-AS2,TDRKH,STON1,GRB10,GRIA1,GRIN2D,CIT,BTN2A1,LINC00839,KAT7,GSTT2,LINC01551,FAM222A,HTR5A,EID2B,ZNF546,LRRC25,DISP2,IL6ST,SLC6A17,ZNF385B,KCNK3,KCNMA1,KIT,NCOA7,MAP2,TM6SF1,MEIS1,KITLG,SCAMP5,MXI1,FXYD6,CCDC13,NEUROD1,NTRK2,NUCB1,ODF2,OPHN1,LOC100128398,GPR137C,PCMT1,PCSK1,PCSK2,PDYN,DUSP26,KCTD15,NLE1,PLCD1,FXYD1,SMIM7,PLTP,PNMA3,C11orf49,TNPO2,PPP2R5E,KANSL1,NKAIN4,PSD,SIDT1,ANKHD1,ZSCAN32,CASTOR1,ACSM5,TTC13,RAB5B,TMEM255A,CCDC40,RALGDS,ATG16L1,RASGRF2,ARID4A,HKR1,RDX,RET,SEC61A2,RNASEL,LGI2,C12orf49,KIRREL1,FBXW7,ZNF671,TCP11L1,STK32B,LRRK2,SYNDIG1,MEG3,HSD11B1L,KCNIP3,YJEFN3,RYR3,PRCD,SEC14L1,ITSN1,FAM102A,PPM1E,ASAP3,DOCK10,FBXO11,ST6GAL1,CLSTN1,SLA,SLC1A3,FAM214B,KANSL3,LRRC55,SLC6A7,SLC8A2,RADIL,SLC11A1,SLC22A4,ABTB1,INTS9,SMARCE1,MBD5,SNRPN,MYO16,KDM4B,SCN3B,DOP1A,WDTC1,TRERF1,KDM4C,PEG10,ZC3H13,C11orf87,ATP10B,POGZ,COLGALT2,EPB41L3,ZC4H2,ZSCAN29,ADHFE1,STX1A,STXBP1,SYT11,VAMP1,SYN1,TAL1,CNTN2,SMG6,SZT2,PHF24,FAM189A1,USP32P1,RNF216P1,TEK,ZFPM2,ITGB3BP,GALNT17,TMEM9,ZFP91,BEX4,PIK3R5,ZNF384,RGMB,ZNF346,TRO,PPIL6,TTTY15,HSPBP1,ZKSCAN5,HIRA,PITPNB,PLPPR2,CCDC136,BEST1,LAT2,TRIM9,NDRG4,LYPD6,ZNF138,PRTFDC1,RGMA,GAL3ST3,WIPF2,FZD3,KAT6A,CASC15,ST8SIA2,SLC4A10,SENP7" MicroRNA hsa-miR-331-5p:mirSVR_lowEffct hsa-miR-331-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.80E-109 1.01E-105 1.29E-108 1.19E-107 289 1236 "ABAT,ASIC1,CLK4,DSCAML1,ADD3,SORCS1,SNX30,PTCHD1,DPY19L2P4,ZNF608,GPR158,TAOK1,GOLGA7B,FAM135A,DPP10,CCDC146,PPFIA2,APAF1,EPB41L5,BCAS1,ASTN1,ATP1B3,N4BP2L1,BCHE,BMPR1B,JAZF1,CAST,SPAG9,CLDN10,SEPT7,CDC27,LRRFIP1,L3MBTL4,DLGAP2,RCBTB2,CHM,PLEKHB1,MS4A7,RAB28,C4orf33,QKI,TMEM184B,SULT4A1,ARMC8,FAM149A,AKAP6,COL9A1,SLC4A7,SLC4A8,ZFP28,FAM171B,CLOCK,AKAP12,HAPLN1,ANKRD44,ABCG1,PDE4DIP,PNPLA8,CYBB,KATNAL2,ZFYVE16,AIF1L,ARMCX4,PITPNC1,HP1BP3,COPS7A,DDX46,SNAP91,SV2B,SRGAP3,EXOG,RAB39B,ABI1,E2F6,EBF1,HIPK3,SIDT2,YAF2,EGFR,MBNL2,GOLGA7,ELAVL4,STARD3NL,EN2,IGSF6,RTN3,GMPR2,NRN1,ARMCX1,ABCA8,SH3YL1,ACSL4,DLC1,FKTN,KIAA1109,FGF11,SCARA3,CAP2,IP6K2,SYNCRIP,JKAMP,SORBS1,APOPT1,ZNF605,PNMA2,FYB1,HRASLS5,GABRA5,GABRB1,GALNT15,CAB39,ILDR2,HBS1L,BRPF3,GCNT2,CYP46A1,GHR,RNPS1,GLRB,HTATSF1,GNG4,GPD2,RAPGEF4,GRIA4,PLCD4,CLASRP,GUCY1A1,UBE2QL1,ZDHHC15,CELF5,SMAP1,IDH3A,C2orf72,C5orf24,RBPJ,KIAA1755,IL6ST,INPP5B,TUBB2B,ITGAV,SLC35G1,KCNK2,A1BG-AS1,IPO5,LAMP2,HECTD2,ARHGAP12,NCOA7,SMAD1,SMAD9,MBNL1,SYT9,LRP1B,MEF2C,KCTD6,KITLG,MN1,NAP1L1,NEUROD1,NRCAM,CHAMP1,OPA1,P2RY1,PAH,PAX6,PCDH9,ZDHHC8,SERPINI1,SSH1,SEMA5B,PIK3C2A,ANLN,FAM218A,RETREG1,PLCL1,PURG,PDZRN4,PMP2,PMP22,MAGEL2,ING3,DRAM2,PPM1B,PPP2R5E,PPP3CB,PRPSAP2,LRRC49,LAMA1,GDPD2,ANKHD1,PTHLH,PTPRG,PTPRO,PTPRZ1,PEX5,PPP2R3C,RAD52,SH3TC2,IQSEC3,RASGRF1,KHDRBS2,ZDHHC14,REV3L,TTLL7,SEC61A2,PBRM1,ZFHX4,RORB,RPE,RPL15,UEVLD,MCMBP,ACER3,CLIP1,RYR3,SEMA6D,ATXN7,CASC3,SCAF8,KIF16B,FNDC3A,R3HDM2,ST6GAL1,CNKSR2,BCAN,SEC31A,SIRT2,SLC14A1,SPHKAP,CPEB4,MAST1,LIMCH1,MBD5,FAM219A,SPATA7,ENKUR,KDM4C,SPTB,TSPYL2,TAB2,TROVE2,LARP4,COBL,TAC1,CAMTA1,CNTN2,SMG6,EHBP1,ZEB1,TRIM2,WASHC4,WDR7,AZIN2,SYNE1,LEFTY2,AKTIP,SLC44A1,TJP1,ACTR6,BHLHB9,HEY2,NPL,SMUG1,STXBP4,RFTN2,SLC35A4,UBE3A,UGT8,VLDLR,RICTOR,GUSBP1,ZIC1,ZNF23,TRIM9,GPR158-AS1,CA10,EMSY,MDH1B,PCDH15,FAM47E,WNK3,SLC17A6,PDSS2,RGS7BP,FAM13C,RNF170,FXR1,SLC4A10,FAM198A" MicroRNA hsa-miR-519d:PITA hsa-miR-519d:PITA_TOP PITA 1.99E-109 1.12E-105 1.43E-108 1.31E-107 233 802 "USP31,SLC24A4,GPR158,USP28,APBB2,USP37,APP,SHTN1,SEMA4G,STK33,MARK4,CAPRIN2,RASL11B,SLC4A4,ATP2B1,ATP2B2,B3GALT2,NOL4,DPY19L3,BCL2L2,NRP2,ARHGEF7,MTMR3,JAZF1,MAP7,USP6,REPS2,DLGAP2,CFL2,SOCS6,B4GALT6,KMT2C,QKI,PCYT1B,SLC25A27,AKAP5,SLC4A7,AHCTF1,ACBD5,ZNF385A,PNKD,CLOCK,CREB5,CRY2,LRIG1,ARHGEF10,CHD5,NRSN1,PPP6R2,RUBCN,DOCK4,DCAF8,RASSF2,IP6K1,PLEKHM1,MFAP3L,HP1BP3,FBXL5,CEP170,MAGI2,SACS,USP3,DNM2,DMTF1,DPYSL2,DRD1,DNAJB6,DYRK1A,E2F5,FAM13A,KMT5B,EIF4G2,TENM1,ELAVL2,EPB41,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,TAOK3,SCML2,MED12L,SUCO,ANKFY1,AFF2,NBEA,ST6GALNAC3,OGA,GAB1,RUNDC3A,RAB30,TNRC6A,RAPGEF4,GRM7,CIT,HAS2,HPS5,KLF12,HLF,SCRT2,JAK1,KCNA1,KCNJ10,KIF5A,CAMK2N2,SFXN5,SYTL4,ARHGAP12,SMAD1,MAP2,CHIC1,LRP1B,MID1,AFF1,XRRA1,MXI1,MYCN,NBL1,NEFH,NEUROD2,NHLH1,GPR137C,CNTN3,PDE3B,PDGFRA,PFKFB3,PFKP,PIK3R1,CCSER2,PRRX1,RETREG2,EPB41L4B,POU3F2,PPARA,PPP1R1A,PPP3CA,PKIA,PKN2,MAPK9,PSD,PTPRD,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,GTDC1,SLC25A36,TMEM100,ST6GALNAC6,AMER2,SALL1,CSRNP3,ATXN1,SCN2A,SCN3A,FAM19A1,FAM102A,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,WDR37,SLC1A2,RUFY2,YPEL4,SLC11A1,TET1,PALLD,TMCC1,FAM126B,MYT1L,ARHGAP26,NPAS3,LMO3,SRPK2,ITPRID2,SMOC1,ERBIN,RGL1,FGD4,SYNE2,PLCB1,TACC1,ANKRD12,CAMTA1,TAL1,FBXW11,TBL1X,TCF4,SYNE1,ZFPM2,AKTIP,THRA,TIAM1,DDHD1,ZFP91,RIMBP2,TNS1,RBFOX2,NR2C2,TRPS1,UBC,UBE3A,VLDLR,TBC1D15,LYPD6,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,CADM2,RGMA,CSDE1,SLC17A7,WIPF2,WNK3,PLSCR4,RGS7BP,FAM13C,MARCH8,PAK5,PHTF2,FXR1,FRMD6,DPF3,ST8SIA2" MicroRNA hsa-miR-4305:mirSVR_lowEffct hsa-miR-4305:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.45E-109 2.50E-105 3.18E-108 2.93E-107 272 1101 "VWA5B2,ABHD6,ACTN1,GPRIN1,ADD2,PNMA8B,ADRB2,KIDINS220,SLC44A5,KLHL13,HACE1,C1QTNF3,SMIM17,ALCAM,BCAR3,BBOX1,GOLGA7B,DPP10,ANK3,C6orf89,AQP4,SPTBN4,ZBTB10,CHID1,EIF4G3,ATP2B1,RNF182,ATP6V0A1,CDK5R1,DST,NIPA1,LDLRAD4,CACNA1B,KALRN,PTBP2,USP6,SEPT7,TIGD7,GPR37L1,CHN2,LHX2,CLTA,TJP2,ABCG2,QKI,SRP14-AS1,SLC4A7,SLC4A8,RCHY1,SEC31B,GDA,LRIG1,MICAL2,CSNK1E,ATRNL1,DZIP3,PPP1R16B,ERC2,CTH,CTNND2,PUM1,CCDC144A,KIAA0408,HDAC9,ARHGAP32,KCTD8,IP6K1,ELMSAN1,ZNF804A,MYEF2,ZC3H11A,NTM,WDR20,ZNF582-AS1,GRIN3A,DMD,CD99L2,SLC12A6,DPYSL2,ABI1,ATN1,DSCAM,GOLT1B,E2F5,AASDH,ATL1,FCF1,KLHL5,FRY,PHF20L1,EIF4G2,EPB41L2,EPHB1,CEP85L,ANKMY1,EYA1,ABCA8,NSRP1,CEP78,TESK2,OLFM1,FGF11,SLC37A3,PDLIM5,FAM49B,ATP2C1,ERGIC3,STAU2,BRSK1,ABLIM2,ZNF512,FYN,GABBR1,GABRG1,ZNF234,SEPT9,ATP8A2,GCNT2,CRCP,SPIN1,MSL3,LILRA2,GPR12,GSN,MAP4K5,CELF3,BACH2,ELOVL5,HMGB1,SCRG1,HTR5A,IDH3A,LRRCC1,IL6R,BRINP3,KCNA1,KCNJ3,KCNJ11,GATD1,KIF2A,KLC1,LAMP2,ARHGAP12,MAOB,MATN3,TM6SF1,MSR1,MYO9A,ZNF862,NAP1L1,RCOR2,NF1,SLC11A2,NTRK2,TBC1D25,IGSF11,DPY19L2P2,PRTG,PDGFRA,OLA1,ABCB1,SERPINE2,RC3H2,LRP12,SCHIP1,PRRX1,MAGEL2,SH3KBP1,MED1,CRLS1,PPP2R5E,PRKACB,MAPK9,GDPD1,RELN,MDGA2,MTMR10,SPDL1,TMEM260,ZSCAN32,PTPRE,PLEKHB2,RBBP6,RADX,ZDHHC14,GTDC1,ZNF532,CCDC25,TMEM100,FBXW7,ATP8B4,LRRK2,AMER2,ATXN2,SFPQ,ITSN1,FNDC3A,ST3GAL3,ANKRD6,SLC1A7,SLC2A5,PPP4R3A,SLC6A1,KANSL3,SLC6A11,CPEB4,GKAP1,SORCS3,SMARCE1,ANKRD36,RIMS1,FNBP1,SPP1,KDM4C,NPAS3,C11orf87,ATP10B,COLGALT2,EPB41L3,ZSCAN29,RGL1,DIP2A,ADHFE1,STXBP1,PRRC2C,KAZN,MCF2L,SATB2,ZEB1,TRIM2,USP22,PCDHB9,PCDHB4,USP32P1,TNS2,SLC44A1,GALNT17,ARL10,ERCC6L2,TNFRSF1B,C5orf64,TP53BP2,TPD52,NPL,RGMB,PRMT8,TRPC1,TRPS1,TTTY15,HIRA,UGT8,BCL2L13,BEST1,CLDND1,ZBTB14,ELFN1,ATP6V0E2,FMN2,GPR158-AS1,REEP1,TMEM198,DPYSL5,LRP8,STOX2,MDH1B,NAV3,EPM2A,PAK5,HNRNPA3,RSPRY1,NLRP3,FAM198A" MicroRNA hsa-miR-10b*:mirSVR_highEffct hsa-miR-10b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.46E-109 2.51E-105 3.18E-108 2.93E-107 271 1093 "KDM5D,ADAR,KLHL32,SLC12A5,SORCS1,ADORA3,INTS2,HFM1,ARHGAP20,PCDH10,ANK1,LCORL,PHF12,PHYHD1,API5,SHTN1,DYNLL1,BACH1,ADGRB2,SCAPER,CACNA1G,OSGIN2,MMD2,CACNG1,VXN,CH25H,MAP7,KRIT1,MTMR7,SLC16A4,C1orf52,CDH18,LOC730101,CDO1,CFL2,SYNPR,CNOT8,NRXN3,NRXN1,NIPBL,CNGA3,CNR1,AKAP6,IFFO1,CHD1L,CRHBP,SNCAIP,SLITRK5,PUM1,DNAJC6,TIAM2,MAGI2,RHOBTB1,PLPPR4,G3BP2,RAB39B,DNM1,HS3ST2,ABCC5,DNM1L,FAM135B,PHC2,ANKRD46,HIPK3,YAF2,FAM13A,PHF20L1,EGFR,MBNL2,KMT5B,ASB3,TMEM35A,EML1,VPS13B,EPHB1,DENND4A,EXTL2,ZNF585B,FCGRT,ZSCAN30,GORAB,SEC24B,FER,FGF13,SUCO,SYNCRIP,RGPD5,NOP56,SMC2,PNMA2,NRG3,BRSK1,ZMAT1,GABRA2,GABRG2,CAB39,FAM120B,ARPP21,DISC1,TUBGCP4,ARFIP1,GK,COPS8,DBF4,GLI2,RAB30,PCDH11X,ZNF638,GNAS,ADGRA3,GPR12,ATP2B1-AS1,GRIA2,PSIP1,NXPH2,VSIG4,CFAP126,HTR5A,SOWAHA,RBPJ,DOCK7,LIX1,IL6ST,ZNF678,LRRTM1,ITGAV,KCNA1,KCNA4,KCNJ3,KLHL23,INSYN2,HECTD2,MEIS1,MEST,MIA2,AFDN,MOBP,MRPL42,SESN3,BLOC1S2,MSR1,MTTP,RSPO2,NAP1L3,NASP,NEUROD1,DNHD1,NTRK3,OPRL1,CLDN11,PAH,PAK3,CNTN3,PDPK1,BEST3,PFKFB2,NLGN3,SSH1,CCSER2,RETREG1,MINDY2,TATDN3,CCDC144B,PPP3CC,PRKCG,GRAMD1C,HYDIN,MASP1,CNNM2,SYTL2,SIDT1,GON4L,MDGA2,CNTLN,TMEM260,ZSCAN32,OCIAD1,PEX2,ACSS3,SLC6A15,ZYG11B,GTDC1,UBR7,TTLL7,SEC61A2,RPRD1A,TMLHE,CARF,NEK11,ATP8B4,ABCA11P,KCNIP1,TRAPPC13,SALL1,SEMA6D,LRFN5,SCG5,NTNG1,FBXO11,R3HDM2,ST3GAL3,NUBPL,WDR37,SLA,RAB3GAP1,SLC12A2,ELMO2,NAXD,ANKRD36,KIF13A,SNRPN,TMCC1,TNIK,DOK5,NMNAT2,LMO3,C11orf87,POGZ,DIP2A,NECAB1,VPS13A,PLCB1,SYT1,ANKRD12,FBXW11,ANO4,TBX15,WSCD1,SATB2,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,AKTIP,ACTR6,ASXL3,TMOD1,C5orf64,TNS1,TPD52,METTL3,PDSS1,RUNDC3B,ZMYND8,ANKRD20A2,RFTN2,CLHC1,RPL7L1,PITPNB,PLEKHH2,VLDLR,RICTOR,ZIC2,FSTL5,UPF3A,VPS35L,PCDH15,CAB39L,WNK3,RGS7BP,AMN1,PAK5,JMJD1C,TRAM2-AS1,ZNF248,SLC4A10" MicroRNA hsa-miR-4264:mirSVR_lowEffct hsa-miR-4264:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.61E-109 2.59E-105 3.29E-108 3.03E-107 328 1580 "TTYH1,ABAT,DGCR6,SYS1,GALNT16,ADD2,BRAP,PNMA8B,ERMN,ADORA2A,LRFN2,HACE1,OSBPL1A,SEMA6A,SPOP,FAM135A,AMPD2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,APOC2,LRRC4C,TNRC6C,PPFIA3,LGR5,MADD,ASPH,CHRD,DYNLL1,ATP1A1,ATP2B1,ZNF582,B3GALT2,DOCK11,ADAM15,SEC11C,PROM1,KSR1,SYNJ2,CASTOR3,SGCE,CDK5R2,MMD2,CA12,CALB1,SYT6,CAST,CARS,CLDN10,METTL6,USP6,P2RX6,SCARB1,CDC25B,CDC27,CDH2,CDH8,LGI1,ADGRG1,CASC2,SLC22A6,FAM189A2,NIPBL,COL9A1,COL9A2,MAGED1,RTTN,CHD1L,CRMP1,ANKRD44,SNCAIP,CST3,CMTM5,GREB1,CFAP61,CTNND1,TOX,DGKB,PABPC5,DBI,DNAL1,ARMCX4,PITPNC1,ZEB2,MFAP3L,HP1BP3,COPS7A,CEP170,GSDME,ALKBH8,NTM,DMPK,RPS6KL1,CPEB2,DRP2,FCF1,APH1A,KMT5B,ELAVL2,TMEM35A,STARD3NL,EPHB1,GPHN,SPEG,CDHR1,PIPOX,RTN3,ADGRV1,EYA1,F8,ARMCX1,SH3YL1,FCGR1A,ZNF589,GORAB,MEX3B,PCYOX1,NELFCD,ERGIC3,CELF1,DACH2,DLL3,PNMA2,MPP6,MEGF10,GABRA2,GABRB3,HBS1L,ZMYND11,ARPP21,IP6K3,NCKAP1,GCNT2,SULT1C4,MSTN,AHDC1,GFAP,ADAM28,GGTA1P,LYVE1,CRCP,TCERG1,RAB30,STARD3,ZNF638,KDM2B,ATF7,LPAR4,PCLO,GRIA1,GRIA4,SERP2,RNF165,MFSD2A,AP4S1,WIF1,RASSF8,HNF4G,LRRCC1,PLD5,IGSF1,DIPK1A,ITGAV,ITPKB,KCND2,KCNJ3,KIF5A,LAMA2,LAMP2,SYTL4,LYPLAL1,MATN3,MEIS1,MIA2,KITLG,MID1,SESN3,ADAM22,MTTP,MYO7A,MYT1,HNRNPM,FXYD6,NAP1L3,CCDC13,NF1,ZNF827,GLIPR1L2,PAK3,PBX1,PDE3B,PDGFRA,PIK3CD,A2ML1,SNX10,ZFYVE21,XRN1,KCTD15,SMIM7,MTRF1L,RC3H2,EXOSC10,POLR2F,FSD1,PPP1R1A,RASGEF1B,PRKACB,CEP41,BCAS3,WBP1L,CNTLN,PTAFR,OCIAD1,PTPRD,PTPRZ1,RAD52,SH3TC2,ATG16L1,NWD1,ARID4A,DBX2,KHDRBS2,ZMAT4,TRIM68,RGS10,RIC8B,CCDC25,TMEM206,ELP2,MRAP2,UEVLD,ACER3,MEG3,ABCA11P,KCNIP2,RTN1,ZNF354C,ZNF331,AP1AR,CSRNP3,SCN2B,SCN4B,SCP2,TNFRSF19,FOXRED1,FAM102A,SH3GL2,KIF16B,CPEB3,NTNG1,FBXO11,ST3GAL3,SMTN,FAM214B,PKNOX2,SLC8A2,SLC12A2,SCMH1,ELMO2,BTBD7,CPEB4,INAVA,MBD5,PALLD,SON,MYCBP2,CDK19,RBM26,SPART,ITPRID2,ZC4H2,NEK4,PHLDB1,KANK1,SYT11,JMJD6,SYP,ANKRD28,TACC1,KAZN,MTCL1,ADGRL3,EHBP1,CUX2,TCF7L2,TRIM2,AZIN2,AKNA,ARHGAP9,CRB1,LEFTY2,AP4E1,ZNF106,HHIP,ACTR6,TLL2,NR2E1,RIMBP2,TNFRSF1B,PIK3R5,SYNPO2,METTL3,FNDC5,ANKRD20A2,ANO5,TTTY15,UBE2H,BCL2L13,NSD2,GUSBP1,SF1,ZBTB14,MICU3,ZNF28,CFAP52,FMN2,LYPD6,DHX33,SEMA3B,PCDH15,DOCK8,CASC15,FAM219B,JMJD1C,ZNF248,SNX14,FRMD6,IFT88" MicroRNA hsa-miR-519e:mirSVR_lowEffct hsa-miR-519e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.84E-109 2.72E-105 3.44E-108 3.17E-107 297 1308 "EMILIN3,SYS1,CSMD3,ADCY2,GALNT13,ADD2,PTCHD1,SYT13,SUGT1P4-STRA6LP-CCDC180,PKP4,APBB1,APC,VAT1L,SHTN1,IGDCC4,SPTBN4,CDK13,PDE8B,STK33,CAPRIN2,DDX3Y,ATP2A2,LINC00847,DCAF5,BID,SYNJ2,RAB29,CACNB4,SLC25A14,VXN,SPAG9,CERS5,ARHGEF1,SCARB1,CD38,SEPT7,LGI1,MAGI1,ASIC3,CHN2,CASC2,SLC24A2,FBXO7,TJP2,QKI,SRP14-AS1,WHRN,SLC35F1,SEC31B,GDA,RGS6,FEZ2,FEZ1,MICAL2,GALNT9,CTH,EDRF1,ZFYVE16,MAML1,IST1,TOMM20,GIT2,YTHDC1,ZNF804A,ZEB2,CEP170,SV2B,NTM,DMD,DMTF1,DPH1,DSCAM,DYRK1A,EDN1,ANKRD46,SYT15,CNNM1,FAM13A,PLXNC1,CERCAM,EMX2,EFS,VPS26C,GMPR2,HSPA12B,FAM198B,ZNF585B,FCGRT,ZSCAN30,KIAA1109,FGF1,FGF11,PCYOX1,SLC37A3,DPYSL4,ARFGAP2,ADGRA1,AP4B1,NRG3,PHYHIPL,GABRA2,GABRB3,CAB39,JPH4,GALR1,ERAP1,LRRC37A6P,GATM,TUBA8,MSTN,KIRREL3,TOX3,RAB40B,DIPK1C,STON1,NUDT21,GRIA1,SERP2,KIF3A,LINC00839,LINC01551,GUCY1B1,SLC2A6,C1orf94,PTGDR2,TLX1,IDH3A,DOCK7,IGSF1,IL6ST,JAK1,KCNA1,KCNJ11,KCNK2,KIF5A,KIT,KTN1,STMN1,FGFBP3,GPR155,CLEC18A,LDLRAD3,LRP1B,MEIS2,SAMD5,ADAM22,MSR1,NRBP2,MTTP,MTR,MYO5A,HNRNPM,NAP1L1,FXYD6,ZC3H12B,NOS1,DNHD1,SLC11A2,P2RX7,GPR137C,PBX1,PDE1B,PDYN,BEST3,PFKFB4,OLA1,DUSP26,XRN1,NLE1,PLCB2,PLP1,SLC25A23,PCDH18,PMP2,SCHIP1,SLC36A4,FAT3,FSD1,PPP2R5E,PPP3CB,HYDIN,SIDT1,GON4L,MDGA2,UHRF1BP1,MTMR10,PTHLH,ELOVL2,OCIAD1,PTPRE,TMEM255A,RALGDS,FAM184A,ZNF493,BSDC1,GTDC1,RFX5,SLC25A36,LGI2,C12orf49,ALG9,ARMC5,CCDC25,ATP8B4,TCP11L1,PTGR2,ST6GALNAC6,KCNIP3,ZNF354C,TRAPPC13,SEMA6D,DRAXIN,ATXN2,ATXN7,HOGA1,SLC30A10,PEAR1,CASC3,MRAS,SUPT20H,SH3GL3,ASAP3,SHMT2,MAGI3,CHD9,PAAF1,LRRC55,YPEL4,SLC8A3,ELMO2,CPEB4,NAXD,SMARCD3,MYH15,RCOR3,KIF13A,SNRPN,UNC80,USP33,SCN3B,TNIK,NMNAT2,C11orf87,SRPK2,STOX1,NEK4,SULF2,MLC1,SLC37A2,C12orf76,SIN3B,TCF7L2,TRIM2,PHF24,FRYL,AHCYL2,DICER1,SIRT1,ZFPM2,CRB1,GALNT17,ZFP91,LRRC8A,KCTD2,TP53BP2,STXBP4,PPIL6,SGK3,HEPACAM,CADM1,RPL7L1,UCHL1,UGT8,SLAIN1,CCDC14,BEST1,TBC1D15,GUSBP1,XPO1,ZNF711,TRIM9,LYPD6,SPHK2,DPYSL5,ZFAND5,PRDM2,NAV3,EPM2A,RGS7BP,GOPC,DOCK8,RTN4,CERS6,TRAM2-AS1,RNF170,DPF3,SENP7" MicroRNA hsa-miR-520c-3p:mirSVR_highEffct hsa-miR-520c-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.85E-109 2.72E-105 3.45E-108 3.18E-107 304 1368 "KIAA1211,PTCHD1,MTUS1,GPR158,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,STX16,DPY19L3,DOCK11,BACH1,DCAF5,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,SGCE,IL33,CA12,CACNA1E,CALB2,CANX,VSTM2A,AIFM1,ZBED1,LGI1,MAGI1,CLGN,CFL2,CHN2,CASC2,TAOK2,ABCG2,C4orf33,AKAP7,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,HAPLN1,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,DCAF8,TOX,DCTN1,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,GRIN3A,HS3ST4,OLIG1,HS3ST2,DMTF1,DRD1,ABCC9,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,FYB1,MEGF11,CAB39,ZMYND11,ARPP21,SALL3,IGSF5,TUBGCP4,ADAM28,GGTA1P,GHR,COPS8,GLDC,TNRC6A,GLUL,ZNF638,MAP7D2,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,FICD,HPS5,C1orf94,ARHGAP36,ZDHHC15,HSP90AA1,SMAP1,MSL1,C5orf24,IGSF1,ITGAV,JAK1,OLFM3,KCNMA1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NUMA1,OCRL,OGG1,OPHN1,PCDH9,PCSK2,PDCD2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PLP1,PRIMPOL,TRHDE,MAPKAP1,PRRX1,SPATA6,DRAM2,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,PTPRD,RAB5B,CEP97,ACSS3,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,TRIM68,GTDC1,FIGN,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,PCMTD2,CCDC102B,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ENKUR,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,CAMSAP2,UNC5D,ADGRL3,TBCEL,CUX2,TCF7L2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,HHIP,AKTIP,GZF1,TIAM1,NR2E1,TNS1,TPD52L2,RGMB,TRPC1,PPIL6,PITPNB,PLEKHH2,VLDLR,PCDH20,FMN2,LYPD6,LAMP5,SYNC,CADM2,RGMA,CSDE1,LINC02210,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,PAK5,CASC15,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-194:mirSVR_highEffct hsa-miR-194:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.12E-109 2.87E-105 3.63E-108 3.35E-107 253 953 "ACHE,ACTN2,NDRG3,PTCHD1,DPY19L2P4,KLHL13,OSBPL8,TAOK1,ALCAM,FAM135A,PITPNM2,DPP10,LRCH2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,ZFYVE28,ZBTB10,TMEM108,ALDH4A1,ATM,STX16,ALDH7A1,SYNJ1,ARHGEF7,MTMR2,SGCE,KALRN,SLC25A14,VSTM2A,PRC1,LDB2,KRIT1,CCNH,CD81,CDC42,LRRFIP1,LGI1,DLGAP1,CFL2,SRSF11,CHN1,KMT2C,ZFYVE9,TJP2,QKI,AKAP6,SLC25A27,BTF3L4,SLC4A8,ABI3BP,AHCTF1,BAG4,TOGARAM2,SLC35F1,SEC31B,ENTPD4,RBM39,MROH8,CSF1,ATRNL1,NCAN,ST18,USP6NL,ARHGAP32,HDAC4,IST1,ELMSAN1,ZEB2,CEP170,MAGI2,SNAP91,WDR20,SLC12A6,DPP6,DRD1,DYRK1A,DNM1L,GOLT1B,E2F5,E2F6,WDPCP,EDN1,CELSR3,MBNL2,KMT5B,AASS,ELAVL3,NRN1,ZNF585B,FDFT1,GORAB,FER,FGF12,CAMSAP1,POLK,SEC23B,IP6K2,ANKFY1,JKAMP,ATP6V1H,ATP2C1,ZNF605,DACH2,STAU2,OGA,ZMAT1,STAG2,GABRB1,GAD1,IQGAP2,INPP5K,NEU3,TUBGCP4,MSTN,BRD8,COPS8,TNRC6A,GRIA2,GRIA4,ATE1,GSTT2,GUCY1B1,GYG1,ZHX1,MSL1,TJAP1,KCND2,KCNN2,KLC1,LAMP2,STMN1,LIMS1,HECTD2,IL17D,MEIS2,MEST,MIA2,MITF,AFDN,WDR49,JAKMIP3,NCAM1,NEUROD1,NPPA,IGSF11,LOC100128398,GLIPR1L2,DPY19L2P2,PFKFB2,OLA1,CDK14,SERPINE2,SCHIP1,RETREG2,MINDY2,PPP3CA,PPP3CB,GRAMD1C,MDGA2,PXK,TMEM260,PTPRD,PTPRZ1,ZNF615,USP47,FAM184A,ARID4A,KHDRBS2,SLC6A15,PBRM1,RNASEL,ZFHX4,SETD5,PNMA8A,GSTCD,FBXW7,SPIN3,ATP8B4,LRRK2,RTN1,TRAPPC13,DGLUCY,SALL1,ATXN7,SCN2A,FNIP1,NLGN4Y,ITSN1,PPM1E,NTNG1,WDR37,ZNF365,SLC1A3,RUFY2,KANSL3,SEPHS1,SLC12A2,BTBD7,ATF7IP,ZFP1,LIMCH1,RIMS1,SNRPN,UNC80,SOX3,SOX5,FNBP1,SP4,PEG10,LMO3,TAB2,CLASP2,SS18,TTBK2,ADHFE1,SYT11,TMEM150C,SYT4,MTCL1,PJA1,CAMSAP2,TMEM136,KLHL4,TBX15,TCEA1,EHBP1,SIRT1,C18orf54,AP4E1,HHIP,SLC44A1,ZFP91,RIMBP2,KAT6B,TRPS1,MICAL1,WRN,RICTOR,TRIM9,EMSY,STOX2,PCDH15,GAL3ST3,WNK3,PARP11,DOCK8,RTN4,UBE3B,ACTR3B,MSRB3,IFT88,CBLN2" MicroRNA hsa-miR-135a*:mirSVR_lowEffct hsa-miR-135a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.66E-109 3.18E-105 4.01E-108 3.69E-107 285 1208 "NCKAP5,KLHL32,ADCY2,TMCC3,GALNT13,ADD2,SORCS1,ADRA1D,OLMALINC,SLC24A4,PCDH19,ADGRF5,MARCH4,MRTFA,PDZD4,APLP1,BCAS1,ASPH,ATP1A2,SLC2A11,MYOM1,TTLL9,BBS2,MPDZ,LINC00906,CACNA1G,WASF1,CA8,CALB1,CALM1,HAP1,VXN,ISPD,CBR1,CBS,SHISA7,INA,CD38,SEPT7,ASIC3,CHM,CASC2,COG1,TPP1,QKI,ARHGEF6,AKAP7,COL4A5,COL11A2,ABI3BP,RBM39,CLIP3,TRIM69,RGS6,OSBPL3,IPCEF1,NCAN,SOCS5,PDE4DIP,CST3,HDAC9,SNPH,DCAF8,ZNF337,TBC1D5,DGKG,SCRN1,DCC,ZNF804A,HEPH,HP1BP3,FBXL5,MAGI2,FBXO25,DDX46,SNAP91,SRGAP3,DLG2,GRIN3A,RAB39B,DMTF1,DTNA,SEZ6L2,EDN1,EDNRA,CNNM1,KLHL5,FSD1L,ABI2,VPS13B,EPB41,EPB41L2,RCAN2,KCNMB2,CDHR1,RRAGB,SIRPB1,EYA1,CD320,MRVI1,FAM198B,TOMM40L,FGF12,CAP2,RGPD5,TACC2,SORBS1,FAM49B,ZNF605,ERGIC3,KHDRBS3,DLL3,ZMAT1,ARPP21,ZNF234,NCKAP1,LRRC37A6P,NEU3,ALDH1L1,TUBGCP4,GFAP,POLL,KCNMB4,GNG4,ATF7,CCDC184,TMEM121B,GRM3,RNF165,ZBTB45,SOX21,ADAMTS6,GUCY1B1,IRAK3,HAS2,HPS5,ZDHHC15,SMAP1,LIX1,KCNK1,KCNK2,KCNMA1,KCNN2,KIT,KLC1,STXBP5,LAMP2,INSYN2,LIFR,VWA5A,GPR155,MAOB,MAP2,MAP6,MAT2A,TM6SF1,MDM4,KCTD6,ERICH3,ZNF680,JAKMIP3,MYO6,MYO9A,NAP1L1,CNOT4,NRCAM,NRGN,SETD4,OGG1,FAM225B,P2RX7,PBX1,PDPK1,ZNF655,ZFYVE21,MTRF1L,PSAT1,ING3,SH3KBP1,RAB39A,WBP1L,CNTLN,PTCH1,ELOVL2,ZIK1,PTPRB,OCIAD1,PEX5,MARCH1,ROGDI,MSANTD2,ZYG11B,TRIM68,RFX4,SEC61A2,LGI2,SUGCT,CARF,SNX22,SPIN3,ATP8B4,SGSM1,ADAL,STK32B,LRRK2,AP1AR,MAPK12,SARS,HOGA1,SCP2,SFPQ,NLGN4Y,KIF16B,ASAP3,FBXO11,FNDC3A,BCAN,ANKRD6,SLC6A1,SMARCE1,RCOR3,MBD5,SNRPN,PDZRN3,SOX2,KIF21B,SP4,NMNAT2,IDI2-AS1,BEX1,TSPYL2,RBM26,RAP1GAP2,NFASC,DIP2A,FNDC9,ASTN2,TACR1,DDHD2,EXOC7,CLASP1,TMEM151B,NSD1,ARHGEF12,FRYL,AHCYL2,RNF216P1,TEK,FAM200B,SIRT1,LEFTY2,AP4E1,AKTIP,FBXL16,TLR4,RIMBP2,CSMD1,SEZ6L,STXBP4,UBE2H,VLDLR,LMF1,PCDH20,ZNF24,KCNT2,FMN2,ZNF138,CELF4,POLR3H,EML6,ZXDA,PRTFDC1,DNALI1,RGMA,STOX2,GAL3ST3,ITM2C,FAM47E,MVB12B,FAM13C,FZD3,CERS6,SLC39A12,DPF3,SOCS4" MicroRNA hsa-miR-605:mirSVR_highEffct hsa-miR-605:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.12E-109 4.00E-105 5.04E-108 4.65E-107 272 1103 "SLITRK1,ADD3,PWWP2A,ADRB2,WDR35,C1QTNF3,FAM135A,OGT,LRCH2,FGD2,ANXA7,GPAM,NT5C3B,SPTBN4,RGS20,CHRD,SLC4A4,TTLL9,RGS9,NRP2,ZNF599,DST,ST3GAL5,ARHGEF7,SCAPER,GPC2,OSGIN2,KALRN,CAMK2B,VXN,CAST,SPAG9,RUNX1T1,CBR1,LDB2,CCNH,LRBA,CDC27,CDC42,CDH2,LRRFIP1,MAGI1,CHM,CASC2,ZBED5,NDST3,QKI,AKAP7,SUMF2,ABI3BP,HS3ST5,CLOCK,HAPLN1,CSF2RA,MICAL2,CSNK1G3,ERC2,UBXN2A,GREB1,DOCK4,GPRASP1,ARHGAP32,KATNAL2,GAPVD1,TCAF1,DGKG,SPATA2,ZEB2,KIAA0753,DLX1,NR1D2,DPP6,PDCD6IP,DTNA,DNAJB6,E2F5,EBF1,WDPCP,EDN3,SGK2,FCF1,FRY,YAF2,PHF20L1,EGFR,MBNL2,TMEM132E,ELAVL4,PAN3,EPB41L1,KCNMB2,CEP85L,F3,CLVS1,FABP7,TMEM132C,FCGR1A,CHST15,FGF14,CAP2,AGAP3,ANKFY1,TRIM16,CELF1,ST6GALNAC3,NSG1,STAU2,DKK3,ACSS1,MSTN,MMADHC,PCDH17,GLS,PCDH11X,KDM2B,OS9,RAB40B,GPM6B,FUT10,PRLHR,LPAR4,CECR2,GRIA2,DIDO1,SERP2,ATE1,FAM19A2,KAT7,LINGO1,ADAMTS6,MAEL,HNRNPK,ZDHHC15,MSL1,IDH3A,C5orf24,NKD1,RBPJ,USP54,JAK2,SLC35G1,KCNA2,KCNC1,KCNK2,KPNA5,STXBP5,STMN1,SFXN5,LMO2,HECTD2,MBD1,EFHB,AFDN,MSI1,ADAM22,ZNF92,MX1,MYT1,NEK1,NEUROD1,NF1,NFE2L2,SLC11A2,PDCD2,PDE3B,PDGFRA,OLA1,KCTD15,PLP1,CDIP1,RC3H2,LRP12,MED1,PPP3CA,MASP1,APTX,SYTL2,PTCH1,ANKHD1,TMEM260,PTX3,TTC13,ZCWPW1,RADX,KHDRBS2,GTDC1,ZNF532,SUGCT,ALG9,CARF,ELP2,ATP8B4,ADAL,ACER3,WLS,ZNF568,NCBP3,AP1AR,CSRNP3,LINC00461,ASIC4,SLC30A10,SEC14L1,SOX6,COPZ1,KIF16B,ST3GAL3,ANKRD6,FAM81A,BTBD3,EPN2,CCDC88A,SLC12A2,CPEB4,MYH15,MBD5,PALLD,DOP1A,MYT1L,TEX2,ZBTB43,DDN,ATP10B,PBLD,POGZ,ZC4H2,DIP2A,VPS13A,ANKRD12,DDHD2,CAMSAP2,ADGRL3,TMEM136,CUX2,SYNE1,TEK,PMS2CL,SLC44A1,ERCC6L2,TMOD1,KAT6B,TPM4,METTL3,TRPC1,TSN,TUBB1,EIF4ENIF1,UBE3A,PITPNB,FLRT2,TOM1L2,ELFN1,ATP6V0E2,FTSJ1,EMSY,PRDM2,PRTFDC1,LINC02210,STOX2,TMEM178A,CIAPIN1,PCDH15,GAL3ST3,KCNAB1,CAB39L,TRIM16L,FAM13C,FZD3,CASC15,JMJD1C,RNF146,SLC4A10" MicroRNA hsa-miR-1289:mirSVR_lowEffct hsa-miR-1289:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-108 5.72E-105 7.21E-108 6.64E-107 289 1244 "DPF1,ACLY,NCKAP5,FAM43B,PTCHD1,OLMALINC,OSBPL6,C1QTNF3,UNC79,FAM135A,LRFN1,ANK1,ANK2,SEMA7A,UPRT,PPFIA3,CDK10,ASPH,TMEM108,ATP1A2,EIF4G3,B3GALT2,TTLL9,ADGRB2,BBS2,FGF17,KSR1,ARHGEF7,NAE1,BSN,RAB29,PTBP2,NGB,CAMK2A,VXN,BRSK2,HIP1R,CBLN1,SEPT7,CHGA,ASIC3,CHN2,CHRM1,JAM2,PPT2,MAP4K4,TMEM155,CNTFR,IQCK,LETMD1,COL11A2,TBPL1,ZNF385A,SLC35F1,CRY2,HINFP,CS,ARHGEF10,CMTM5,UBXN2A,CTH,CTNND1,NRSN1,KATNAL2,ARHGAP24,TM9SF4,PHYHIP,IP6K1,HEPH,MYEF2,C2CD2L,CEP170,RHOBTB1,NTM,TMCC2,KIF19,HS3ST4,RPS6KL1,DNM2,DPH1,CASP8AP2,DYRK1A,DNM1L,EBF1,USH1C,HEYL,YAF2,APH1A,EGFR,GOLGA7,KCTD3,CERCAM,ELN,COQ7,STX2,SRRM1,DENND4A,NCALD,KATNAL1,MRVI1,HSPA12B,CORO2B,FCGRT,OLFM1,FGF12,BAIAP2,FHL1,AGAP2,SLC37A3,AFF2,AKAP3,DACH2,ST6GALNAC3,TVP23A,FYB1,MEGF10,GAB1,GAD1,ARPP21,ATP8A2,GBX2,TUBGCP4,CYP46A1,GGT5,TTBK1,TCERG1,GLI2,DCLK2,WDFY3-AS2,CCDC184,STON1,GRB10,GRIA1,ADAMTS13,GRIK5,NR3C1,GRM7,FAM19A2,RNF165,AP4S1,PSIP1,GUCY1B1,SYNPO,TLX1,NEGR1,CPT1C,SHISA6,SMAP1,EID2B,LINC00667,LIX1,IL11RA,ZNF385B,ITPKA,KCNA1,KCND1,KCNMA1,KIF5C,KLRC2,L1CAM,LAMA2,SYTL4,CLEC18A,MARK1,LDLRAD3,MIA2,AFF1,CD200,MSR1,MYO9A,NF1,NME4,NOVA1,NUMA1,OGDH,SNTG1,PDE1A,PDE1B,ENPP2,BEST3,CCSER2,XRN1,PKM,PMP22,CDIP1,SDK2,EPB41L4B,PPP2R5C,RANBP3L,PKIA,HYDIN,CYBC1,PSMA6,WDR25,TMEM260,ZSCAN32,PTPRD,ZSCAN2,ZNF793,ROGDI,BSDC1,TRIM68,PRRT2,ARHGEF10L,EXD2,ROBO2,NEK11,ATAT1,RTN1,ATXN7,SCN2A,FAM19A1,SCP2,TRIM46,STUM,FOXRED1,RUFY2,SLC12A2,SCMH1,ATF7IP,SPHKAP,SLC22A4,MAST1,SMARCC2,UNC80,FAM219A,WDTC1,SOX1,CLUAP1,KIF1B,ZBTB43,NFASC,SRPK2,CLASP2,POGZ,ITPRID2,ADHFE1,SYNE2,ARC,TAC1,SEMA4A,MLST8,CUX2,SZT2,NAT16,SLC19A3,TNS2,AHCYL2,HIF3A,TF,MTMR14,TLL2,TMPO,KCTD2,PRRT1,C5orf64,TNS1,SEZ6L,TPM1,CDK20,C9orf85,TPM4,PRMT8,SMUG1,TMPRSS5,TSC1,CADM1,AMOT,OSBP2,BEST1,ZBTB14,ZIC2,PLPP4,SLC26A10,ZBTB38,ZNF213,SLC30A3,GDPD5,LINC02210,STMN4,PRDM8,SCG2,UBE3B,ZNF248,RNF170,PIANP,CBLN2,SOCS4,PRRT4" MicroRNA hsa-miR-518a-5p:mirSVR_highEffct hsa-miR-518a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-108 6.90E-105 8.67E-108 7.98E-107 298 1321 "ACLY,METAP1D,XKR4,PLEKHH1,ADRB2,MTUS1,KLHL13,PCDH19,SRPX,DPP10,PHF12,APBA2,EPB41L5,CDC14B,MIER1,CDK13,ASCL1,STK33,DDX3Y,ATM,ATP1A2,ATP2B1,ZNF583,ADAM23,KSR1,DST,SYNJ2,LINC00906,SCAPER,MTMR2,CA12,CALM1,PRC1,LGI1,MAGI1,SYNPR,NRXN1,NIPBL,CNGA3,TMEM155,AKAP7,FAM149A,ACBD5,ZNF521,ZFP28,CNRIP1,CLOCK,ENTPD4,RNF14,GDA,ARHGEF10,SOCS5,ERC2,PHF14,CTH,CFAP61,PUM1,DOCK4,FRMPD4,IST1,DAPK1,IP6K1,DCC,PITPNC1,DNAJC6,ZEB2,FBXL5,BLOC1S6,RABGAP1L,WDR20,CHRDL1,MED12,NR1D2,DPYSL2,DSCAM,GOLT1B,AASDH,EDN3,EDNRA,PHF20L1,MBNL2,KMT5B,EGR3,EIF4G2,PLEKHA1,ELAVL4,PAN3,ENO2,VPS13B,EPHA5,NCALD,TLR7,EYA1,F5,CLVS1,ACSL4,DLC1,CEP78,TOMM40L,GORAB,SLC9B2,FGF12,FGF13,FGF14,FOXO3,C2orf88,NBEA,ZCCHC17,ATP2C1,ST6GALNAC3,NSG1,DLL3,STAG2,DKK3,CPLX1,GATM,MSTN,ADAM28,PPARGC1A,RND1,MSL3,FERMT2,GPM6B,FUT10,GPR12,ATP2B1-AS1,DIDO1,GRM7,SOX21,IRAK3,RASSF8,GPR45,MIER3,HMGB1,SHISA6,SMAP1,IRF8,ZNF181,ZNF678,KCND2,KCNK2,KCNMA1,KCNN3,KIF5A,KIT,IPO5,STXBP5,INSYN2,LIMS1,ZNF667-AS1,MAOB,MBD1,MBNL1,MEF2C,SRSF12,MOG,SESN3,BLOC1S2,MYCN,PABPC1L2A,NCAM1,NEUROD1,NF1,NOVA1,LRIT2,TBC1D25,OGDH,OLR1,OPHN1,PAK3,PDGFRA,GPR85,PFKFB4,HERC2P3,NALCN,PIK3C2A,NOMO2,A2ML1,JAKMIP1,SMOX,PMP22,MAPKAP1,SEPT4,MBOAT7,EPB41L4B,PPM1B,PPP2R5E,PPP3CB,PRKACB,PRKCB,QRICH1,OCIAD1,PTPRG,TMEM255A,SLC25A48,CCDC40,SH3TC2,ARID4A,ZYG11B,RET,GTDC1,KCTD17,ARHGEF10L,NUDT11,RPRD1A,CCDC82,ROBO1,ELP2,FBXW7,BAALC,SPIN3,STK32B,MAP6D1,ATAT1,WLS,KCNIP2,CLIP1,TRAPPC13,AP1AR,SALL1,MIR124-2HG,SEMA6D,SCN4B,SCP2,CASC3,SH3GL2,DOCK10,CHD9,FNDC3A,FHOD3,ZNF365,SLC1A6,WDR47,RUFY2,SEPHS1,SLC8A3,CPEB4,NAXD,RCOR3,LIMCH1,RIMS1,PALLD,UNC80,SOX5,ZCCHC24,HECW1,SPP1,KDM4C,BEX1,KIF1B,RAP1GAP2,LHPP,SRPK2,TAB2,ZNF302,ZC4H2,LRRC4,AJAP1,FGD4,PRRC2C,SYNE2,VAMP1,VPS13A,SYPL1,SLC37A2,FBXW11,TBX15,TCF4,SATB2,ZEB1,TCF12,SYNE1,SLC19A3,PCDHB4,TEK,ZFPM2,BHLHB9,TMPO,C9orf85,RGMB,TRO,TRPC3,P2RY12,AGMO,PLPPR5,WNK1,CA10,MFF,ADAMTS9,TMEM163,MVB12B,RGS7BP,FAM13C,PHTF2,ADAMTSL3,PIANP,SLC4A10,SENP7" MicroRNA hsa-miR-527:mirSVR_highEffct hsa-miR-527:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-108 6.90E-105 8.67E-108 7.98E-107 298 1321 "ACLY,METAP1D,XKR4,PLEKHH1,ADRB2,MTUS1,KLHL13,PCDH19,SRPX,DPP10,PHF12,APBA2,EPB41L5,CDC14B,MIER1,CDK13,ASCL1,STK33,DDX3Y,ATM,ATP1A2,ATP2B1,ZNF583,ADAM23,KSR1,DST,SYNJ2,LINC00906,SCAPER,MTMR2,CA12,CALM1,PRC1,LGI1,MAGI1,SYNPR,NRXN1,NIPBL,CNGA3,TMEM155,AKAP7,FAM149A,ACBD5,ZNF521,ZFP28,CNRIP1,CLOCK,ENTPD4,RNF14,GDA,ARHGEF10,SOCS5,ERC2,PHF14,CTH,CFAP61,PUM1,DOCK4,FRMPD4,IST1,DAPK1,IP6K1,DCC,PITPNC1,DNAJC6,ZEB2,FBXL5,BLOC1S6,RABGAP1L,WDR20,CHRDL1,MED12,NR1D2,DPYSL2,DSCAM,GOLT1B,AASDH,EDN3,EDNRA,PHF20L1,MBNL2,KMT5B,EGR3,EIF4G2,PLEKHA1,ELAVL4,PAN3,ENO2,VPS13B,EPHA5,NCALD,TLR7,EYA1,F5,CLVS1,ACSL4,DLC1,CEP78,TOMM40L,GORAB,SLC9B2,FGF12,FGF13,FGF14,FOXO3,C2orf88,NBEA,ZCCHC17,ATP2C1,ST6GALNAC3,NSG1,DLL3,STAG2,DKK3,CPLX1,GATM,MSTN,ADAM28,PPARGC1A,RND1,MSL3,FERMT2,GPM6B,FUT10,GPR12,ATP2B1-AS1,DIDO1,GRM7,SOX21,IRAK3,RASSF8,GPR45,MIER3,HMGB1,SHISA6,SMAP1,IRF8,ZNF181,ZNF678,KCND2,KCNK2,KCNMA1,KCNN3,KIF5A,KIT,IPO5,STXBP5,INSYN2,LIMS1,ZNF667-AS1,MAOB,MBD1,MBNL1,MEF2C,SRSF12,MOG,SESN3,BLOC1S2,MYCN,PABPC1L2A,NCAM1,NEUROD1,NF1,NOVA1,LRIT2,TBC1D25,OGDH,OLR1,OPHN1,PAK3,PDGFRA,GPR85,PFKFB4,HERC2P3,NALCN,PIK3C2A,NOMO2,A2ML1,JAKMIP1,SMOX,PMP22,MAPKAP1,SEPT4,MBOAT7,EPB41L4B,PPM1B,PPP2R5E,PPP3CB,PRKACB,PRKCB,QRICH1,OCIAD1,PTPRG,TMEM255A,SLC25A48,CCDC40,SH3TC2,ARID4A,ZYG11B,RET,GTDC1,KCTD17,ARHGEF10L,NUDT11,RPRD1A,CCDC82,ROBO1,ELP2,FBXW7,BAALC,SPIN3,STK32B,MAP6D1,ATAT1,WLS,KCNIP2,CLIP1,TRAPPC13,AP1AR,SALL1,MIR124-2HG,SEMA6D,SCN4B,SCP2,CASC3,SH3GL2,DOCK10,CHD9,FNDC3A,FHOD3,ZNF365,SLC1A6,WDR47,RUFY2,SEPHS1,SLC8A3,CPEB4,NAXD,RCOR3,LIMCH1,RIMS1,PALLD,UNC80,SOX5,ZCCHC24,HECW1,SPP1,KDM4C,BEX1,KIF1B,RAP1GAP2,LHPP,SRPK2,TAB2,ZNF302,ZC4H2,LRRC4,AJAP1,FGD4,PRRC2C,SYNE2,VAMP1,VPS13A,SYPL1,SLC37A2,FBXW11,TBX15,TCF4,SATB2,ZEB1,TCF12,SYNE1,SLC19A3,PCDHB4,TEK,ZFPM2,BHLHB9,TMPO,C9orf85,RGMB,TRO,TRPC3,P2RY12,AGMO,PLPPR5,WNK1,CA10,MFF,ADAMTS9,TMEM163,MVB12B,RGS7BP,FAM13C,PHTF2,ADAMTSL3,PIANP,SLC4A10,SENP7" MicroRNA hsa-miR-1:mirSVR_highEffct hsa-miR-1:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-108 7.16E-105 8.98E-108 8.28E-107 286 1220 "RALGAPA1,ABHD6,KDM5D,NDRG3,ADAR,SLITRK1,HACE1,ALCAM,ARHGAP20,OGT,CCDC146,MAP4K3,PPFIA2,APC,UPRT,ALS2,API5,MIER1,TMEM263,ARSF,ASPH,TMEM108,ZNF582,FGF17,BMPR1B,SYNJ1,FUBP1,JAZF1,IL33,CA8,KALRN,SEPT7,CDC42,LGI1,L3MBTL4,MAGI1,UBE2L6,CHN2,CLCN3,CLTC,C4orf33,LY86,CNN3,COL4A5,SLC4A8,AHCTF1,BAG4,SLC35F1,CREM,CREB5,RNF14,C1QL2,CRYM,PDE4DIP,DCAF8,MATR3,KCTD8,DGKB,YTHDC1,JAKMIP2,ELMO1,TIAM2,SMG7,PLPPR4,DLX1,DRD1,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,EDNRA,EDNRB,SYT15,MRO,KMT5B,BSCL2,TMEM35A,EN2,EPHB1,KCNMB2,RABEPK,MRPL37,CDKL3,ADGRV1,ABCA8,CEP78,CHST15,FER,POLR1B,FGFR1,SEC23B,IP6K2,ANKFY1,NELFCD,NBEA,UFM1,DACH2,ST6GALNAC3,FYB1,GABRA3,ILDR2,DENND2A,GAD2,HIGD1B,ZNF559,LRRC37A6P,KIAA1841,DNER,ARFIP1,PCDH17,PPARGC1A,GLS,FERMT2,WDFY3-AS2,ADGRA3,GPD2,GPR17,MCHR1,GRM3,ZNF496,RNF165,LINC01551,PSIP1,RASSF8,MIER3,HMGCR,HNRNPK,ZDHHC15,HSP90AA1,IGF1,LIX1,DIPK1A,INSM1,SLC35G1,METTL21A,KCNK2,KIF2A,STXBP5,KTN1,LAMP2,PAXBP1,MAP2,MEIS1,MRPL42,SCG3,MYO9A,PABPC1L2A,NEUROD1,SLC11A2,HCN1,ZNF713,GPR137C,SNTG1,PDCD2,PIRT,PDGFRA,ENPP2,GNG2,CDK14,GDAP1L1,NALCN,CCSER2,KCTD15,PURG,C11orf49,PMP22,TRHDE,SCHIP1,MED1,MINDY2,PRKACB,MAPK3,PLPPR1,TMEM260,ZIK1,OCIAD1,PTPRG,SUSD4,MSANTD2,SLC6A15,CRTAC1,RGS7,RIT2,SLC25A36,NUDT11,EXD2,C12orf49,CARF,GSTCD,FBXW7,SPIN3,ACER3,KCNIP3,ZNF568,AP1AR,SCP2,ASRGL1,MRAS,TRA2B,ITSN1,SH3GL3,FNDC3A,ANKRD6,ZNF365,PEX26,SLC6A9,SLC6A11,SLC8A1,RAB3GAP1,SLC15A2,EFHD1,SORCS3,ANKRD36,SNAP25,SNRPN,USP33,SOX5,SP2,TEX2,RBM26,NPAS3,SAMSN1,LARP4,SS18,NXT2,STAU1,SYN2,POPDC3,TACR1,ALG1,WWC1,ANO4,TCF7,TRIM2,CLASP1,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,LRRC8A,SEZ6L,NPL,TPM3,SYNPO2,TRIO,AMACR,STXBP4,RFTN2,TTC3,TMEFF2,RPL7L1,FAM155A,UBE2H,AMOT,TBC1D15,LMF1,NSD2,ZNF24,LYPD6,WNK1,STOX2,TMEM178A,HPS4,WNK3,SLC17A6,PARP11,PHTF2,CASC15,ADAMTSL3,TIGD6,MSRB3,ZDHHC20,NETO2,SLC4A10,CPNE4" MicroRNA hsa-miR-626:mirSVR_lowEffct hsa-miR-626:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-108 1.33E-104 1.66E-107 1.53E-106 317 1490 "ASIC2,ACLY,CLK4,GPRIN1,PLEKHG5,ADD1,CDC7,FZD9,ADRA1D,BEND6,AP2A2,PCDH19,ADGRF5,ALAD,SEMA6A,SPOP,ALCAM,ZFAT,LRCH2,USP28,PHF12,APBB2,EPB41L5,UPRT,VAT1L,LRRC4C,USP37,SFMBT2,ARNTL,CDK13,MARCH3,ATP2A2,ATP2B3,ADAM15,BACH1,BARD1,BBS2,BCL7A,DCAF5,ARHGEF7,WASF1,CA8,CACNA1A,CACNB4,KALRN,VXN,VSTM2A,RHBDL1,CCKBR,CD86,ARHGEF1,ENTPD6,C1orf52,LRRFIP1,NUMBL,RCBTB2,CHM,MS4A7,TPP1,DGCR9,SRP14-AS1,CNGA3,SUMF2,SMARCAL1,CHD1L,CRY2,MROH8,TENM4,RGS6,CSF2RA,SEC24C,CSNK1E,OSBPL3,PDE4DIP,CST3,KIAA0040,NRSN1,RUBCN,BOC,DOCK4,GPRASP1,HDAC4,TOX,TBC1D5,LIN54,SIRPA,ELMSAN1,ZEB2,CNIH3,HP1BP3,RUSC2,LYPD1,DDX46,ALKBH8,SMG7,SRGAP3,NTM,SGSM2,FAM107B,DLX1,EXOG,GRIN3A,DMD,OLIG1,DNAH9,CDON,SLC12A6,DPP6,EDN3,HIPK3,SEMA3D,PHF20L1,COPS4,RGS17,SRRM1,MRPL37,PPP1R1B,SPSB4,FGFR3,CAMSAP1,FOLH1,ZCCHC17,KHDRBS3,OGA,SDCBP2,STAG2,MEGF11,GABRB1,ARPP21,INPP5K,LRRC37A6P,KIAA1841,ALDH1L1,GGT7,HPGDS,RAB30,ZNF638,PSRC1,GPM6B,ATF7,EML4,GRB10,SPACA9,PRDM5,GRM7,CLASRP,RNF165,TMEM25,FAM107A,UBE2QL1,ZHX1,NXPH2,MAN1B1,BACH2,HMGCL,HMGCR,HNRNPK,OPALIN,SMAP1,FAAP20,IRF8,RBPJ,KIAA1755,SCIN,BRINP3,KCNMA1,KCNN1,CREG2,HECTD2,SYT9,LDLRAD3,MEIS1,AFDN,LAYN,MYO7A,MYO9A,NDP,NF1,NFYA,CNOT4,NOVA1,SMIM11A,HCN1,OGG1,ZDHHC22,PBX1,PCSK5,DUSP26,CCSER2,GPSM2,FAM216A,PLEC,PRIMPOL,ING3,FAT3,NXPH1,POU6F1,MAPK3,MAPK4,MAPK9,GRAMD1C,WBP1L,SIDT1,MDGA2,WDR25,NCR3LG1,BDNF-AS,PTPRO,FAM120C,ZSCAN2,TUG1,ACSS3,RALGDS,SH3TC2,RAP1GAP,ZDHHC14,RDX,SLC6A15,ZYG11B,GTDC1,RFX5,RLBP1,NUDT11,MRAP2,SNX22,BAALC,SPIN3,TCP11L1,KCNIP2,RXRA,S100B,SEMA6D,CSRNP3,ATXN7,SCN2B,FAM19A1,PRCD,SCP2,PEAR1,SCG5,SH3GL2,PPM1E,CHD9,ST6GAL1,CLSTN1,SLA,RPH3A,PPP4R3A,SMTN,SEPHS1,SLC15A2,SLC20A2,SLCO1A2,ARFGAP1,SORCS3,SMARCE1,TMCC1,KDM4B,MYT1L,BDP1,KDM3A,CLUAP1,HECW1,NPAS3,NFASC,TAB2,STOX1,SS18,NCDN,ADHFE1,KLHL7,NECAB1,FGD4,C3orf70,TACC1,DDHD2,SMG6,TCF7,ZEB1,TPCN2,CLASP1,RALYL,ARHGEF12,CRTC1,PMS2CL,ITGB3BP,LEFTY2,THRA,TIE1,C9orf85,ELP5,TRO,TRPC1,KCNE5,TSC1,CLHC1,HIRA,CADM1,OSBP2,VLDLR,SLC13A3,SF1,TRIM9,FMN2,TCEAL7,DPYSL5,SPIRE1,LAMP5,ZFAND5,UPF3A,LRP8,URM1,LINC00632,C12orf4,FBXO36,MSRB3,LAS1L" MicroRNA hsa-miR-320c:mirSVR_highEffct hsa-miR-320c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.77E-108 1.56E-104 1.95E-107 1.79E-106 306 1394 "ABCF1,KCNH8,SYN3,ERMN,SLC44A5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,SHTN1,MIER1,CDK13,ASPH,ZBTB10,TMEM108,DPY19L3,SNAI3-AS1,CFLAR,KSR1,CA8,CACNA1E,PTBP2,SLC25A14,VXN,SPAG9,MAP7,CBLN1,CBR1,LDB2,CCNH,MTMR7,INA,C1orf52,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,ARHGEF6,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CNRIP1,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CX3CR1,CCDC144A,HDAC9,GPRASP1,FRMPD4,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,FAM107B,DLX1,RAB39B,USP3,NR1D2,DOCK2,GNE,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,EFS,CDKL3,ADGRV1,EYA1,NRN1,WAC,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,CAP2,ANKFY1,COQ5,TACC2,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,NRG3,ZMAT1,STAG2,GABRB1,CAB39,ZMYND11,B4GALNT1,SYT17,C15orf41,DISC1,DNER,ARFIP1,DBF4,GLYR1,MAP7D2,INSM2,LOXL3,GRIA4,BVES,MAEL,HAS2,ARHGAP36,VSIG4,HMGB1,GABARAPL2,AGBL5,NEGR1,SMAP1,MSL1,SOWAHA,IGSF1,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,SESN3,ADAM22,CTNNA3,MXI1,NELL2,NF1,CNOT4,GPR88,PBX1,PCDH9,PCSK2,PDE3A,PDE3B,CYTL1,HMGCLL1,RC3H2,PRRX1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,PPP3CB,PRKCG,MAPK9,GRAMD1C,APTX,MDGA2,CNTLN,PLPPR1,PTPRG,TMEM255A,SH3TC2,RBBP6,VEPH1,ZDHHC14,RFX4,RGS10,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,TMEM100,RPL15,ZC3H14,ZNF671,ADAL,WLS,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SELL,SUPT20H,HSPA4L,ITSN1,FERMT1,HKDC1,MAGI3,FBXO11,FNDC3A,SLITRK3,CNKSR2,WDR47,SLC6A8,CPEB4,SORCS3,CDK5RAP2,LIMCH1,CMTR2,PALLD,SON,WDTC1,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,TAC1,ATP11A,CAMSAP2,FBXW11,KLHL4,SIN3B,SATB2,ZFP90,TRIM2,WASHC4,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,ZFP91,KAT6B,TPD52L2,TPM1,TPM3,PRMT8,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,UBE3A,FRRS1L,PITPNB,VLDLR,GUSBP1,XPO1,XRCC4,ZIC3,ANKS1B,EMSY,PRTFDC1,PRDM10,PPP1R3F,SLC17A6,GOPC,ST7,PAK5,HNRNPA3,PHTF2,NLRP3,SSPN" MicroRNA hsa-miR-450b-3p:mirSVR_lowEffct hsa-miR-450b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-108 1.72E-104 2.16E-107 1.99E-106 299 1334 "ABAT,ABCF1,EMILIN3,NCKAP5,NBAT1,GALNT13,SORCS1,ADORA1,HECW2,OSBPL1A,AMPD2,ZFAT,CDC42BPA,EP400,APLP1,CACHD1,TNRC6C,PCDHGB4,ZBTB10,ASTN1,TMEM108,SLC4A4,NOL4,KSR1,ARHGEF7,LINC00906,CASTOR3,KALRN,SPAG9,ZNF501,USP6,MAGI1,CDO1,ZBED5,DLGAP3,NRXN3,DNAJB5,HECTD1,CNN3,COL9A2,ABI3BP,TOGARAM2,MFSD4A,SLC35F1,CLOCK,CREM,RBM39,CLIP3,CSF2RA,NCAN,PLXNA4,CFAP61,DCAF4,CCDC144A,BOC,RIPOR2,CENPL,LIN54,IST1,TOMM20,DNAL1,C8orf34,ZEB2,MYEF2,MAGI2,RHOBTB1,SV2B,KIF19,CHRDL1,DLG2,DYNC1I1,MAMLD1,ABCC5,WDPCP,EDNRB,CELSR3,FAM13A,AASS,CERCAM,SPEG,RASL12,PTK2B,FGF1,PRKAG2,HPCAL4,SYNCRIP,ANKFY1,NOP56,CELF1,DACH2,B3GAT1,ABLIM2,FYB1,MEGF11,GABRB3,BRPF3,ARPP21,GHDC,DISC1,STARD10,ZNF638,LNX1,WDFY3-AS2,FUT10,LILRA2,STON1,GRM1,GRM2,GRM5,GSTM5,ATOH8,PACSIN2,DHX35,FAM95B1,SOWAHA,SCRT2,ITGAM,SLC35G1,OLFM3,KCNB1,KCNK2,KIF2A,STMN1,PAXBP1,SYTL4,VWA5A,FGFBP3,SMAD1,GPR155,C1orf194,MATN3,MEF2C,MID1,PPM1L,MITF,CD200,MPP2,ERICH3,ADAM22,TMEM249,ZNF92,ZNF862,FXYD6,NCAM1,NHLH1,VWA2,HCN1,OPCML,OPHN1,SNTG1,DPY19L2P2,PCDHGC3,CDK18,PDE4D,PDYN,GNG2,GDAP1L1,ZNF655,PKM,NLE1,SLC25A23,HMGCLL1,PLXNB1,MAPKAP1,RC3H2,LRP12,PPARA,PRKAB2,CNNM2,BCAS3,PTK2,ZIK1,OCIAD1,PTPRH,PEX2,TUG1,TMEM231,KHDRBS2,RDX,CRTAC1,TRIM68,GTDC1,RGS7,KLHL11,RERGL,SETD5,NEK11,ZC3H14,GLDN,SYNDIG1,MEG3,HUNK,ATAT1,SEMA6D,ATXN7,SCN2A,LRRTM4,SCP2,TNFRSF19,R3HDM2,BCAN,NLGN1,SMTN,KDM4D,SLC8A1,SLC8A3,KBTBD4,SLC12A4,BTBD7,ATF7IP,SPHKAP,ZFP1,ANKRD36,RIMS1,MBD5,USP33,DOP1A,ZSWIM8,SP4,HECW1,PEG10,RBM26,COLGALT2,SMOC1,LARP4,STAU1,SULF2,SEPT3,NSFL1C,SYT11,FGD4,JMJD6,TACC1,PJA1,CAMTA1,VWA3A,SIN3B,KIAA0930,TCF7,RPGRIP1L,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,FAM189A1,TEK,DICER1,ENHO,FAM124A,PIK3R5,CDK20,RGMB,METTL3,ELP5,STXBP4,GORASP1,BCL2L13,MEAF6,CCDC14,BEST1,TBC1D15,NSD2,XPO1,SF1,ZIC3,ZNF711,ZNF540,FMN2,ZBTB16,POLR3H,DPYSL5,DHX33,EMSY,GDPD5,LINC02210,XKR7,HPS4,CAB39L,PLSCR4,C12orf4,DNAH10,DOCK8,UBE3B,HNRNPA3,TRAM2-AS1,ZNF248,VANGL2,NETO2,NETO1" MicroRNA hsa-miR-320d:mirSVR_highEffct hsa-miR-320d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.42E-108 1.92E-104 2.40E-107 2.21E-106 303 1369 "ABCF1,KCNH8,SYN3,ERMN,SLC44A5,PCDH19,KIAA1324,SORCS2,HFM1,SEMA6A,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,SHTN1,MIER1,CDK13,ASPH,ZBTB10,TMEM108,DPY19L3,SNAI3-AS1,CFLAR,KSR1,CA8,CACNA1E,PTBP2,SLC25A14,VXN,SPAG9,MAP7,CBLN1,CBR1,LDB2,CCNH,MTMR7,INA,CDH2,LRRFIP1,CCPG1,RCBTB2,ARHGAP22,EPS15L1,CLCN3,C4orf33,QKI,ARHGEF6,CNTN1,AKAP6,SLC4A8,ABI3BP,BAG4,CNRIP1,CLOCK,ANKRD44,PDE4DIP,GREB1,PUM1,CX3CR1,CCDC144A,HDAC9,GPRASP1,FRMPD4,KIF26A,IST1,DGKB,DBN1,ARMCX2,RHOBTB1,DLX1,RAB39B,USP3,NR1D2,DOCK2,GNE,DTNA,ECM2,MAMLD1,GOLT1B,E2F5,EBF1,EDNRA,HIPK3,RASGRP1,CELSR3,PHF20L1,KMT5B,EGR3,PLXNC1,PAN3,DENND4A,IGSF6,EFS,CDKL3,ADGRV1,EYA1,NRN1,WAC,RPS6KC1,ACSL4,POLR1B,PRKAG2,MEX3B,CAP2,ANKFY1,COQ5,TACC2,FAM49B,ATP2C1,CSPG5,STAU2,HHIPL1,DOT1L,NRG3,ZMAT1,STAG2,GABRB1,CAB39,ZMYND11,B4GALNT1,SYT17,C15orf41,DISC1,DNER,ARFIP1,DBF4,MAP7D2,INSM2,LOXL3,GRIA4,BVES,MAEL,HAS2,ARHGAP36,VSIG4,HMGB1,GABARAPL2,AGBL5,NEGR1,SMAP1,MSL1,SOWAHA,IGSF1,JAK2,CDH20,IPO5,LAMP2,SYTL4,HECTD2,NCOA7,PACRG,SMAD9,MARK1,MAT2A,AQP11,MBNL1,MEIS2,KITLG,MITF,MN1,SAMD5,SESN3,ADAM22,CTNNA3,MXI1,NELL2,NF1,CNOT4,GPR88,PBX1,PCDH9,PCSK2,PDE3A,PDE3B,CYTL1,HMGCLL1,RC3H2,PRRX1,MAGEL2,EPB41L4B,MINDY2,PPM1B,PPP2R2C,PPP3CB,PRKCG,MAPK9,GRAMD1C,APTX,MDGA2,CNTLN,PLPPR1,PTPRG,TMEM255A,SH3TC2,RBBP6,VEPH1,ZDHHC14,RFX4,RGS10,SLC25A36,RNASEL,EXD2,GSTCD,ROBO2,ELP2,MRAP2,TMEM100,RPL15,ZC3H14,ZNF671,ADAL,WLS,NCBP3,SEMA6D,ATXN2,SCP2,SEC14L1,SELL,SUPT20H,HSPA4L,ITSN1,FERMT1,HKDC1,MAGI3,FBXO11,FNDC3A,SLITRK3,CNKSR2,WDR47,SLC6A8,CPEB4,SORCS3,CDK5RAP2,LIMCH1,CMTR2,PALLD,SON,WDTC1,KDM4C,ZC3H13,RBM26,LMO3,TROVE2,SS18,NXT2,DIP2A,KANK1,SYT1,C12orf76,TAC1,ATP11A,CAMSAP2,FBXW11,SIN3B,SATB2,ZFP90,TRIM2,WASHC4,CLASP1,SYNE1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY1,TK2,ZFP91,KAT6B,TPD52L2,TPM1,TPM3,PRMT8,SMUG1,PDSS1,PPIL6,CLHC1,FAM155A,UBE3A,FRRS1L,PITPNB,VLDLR,GUSBP1,XPO1,XRCC4,PCDH20,ZIC3,ANKS1B,EMSY,PRTFDC1,PRDM10,PPP1R3F,SLC17A6,GOPC,ST7,PAK5,HNRNPA3,PHTF2,NLRP3,SSPN" MicroRNA hsa-miR-499-5p:mirSVR_highEffct hsa-miR-499-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.36E-108 2.45E-104 3.06E-107 2.82E-106 287 1234 "KCNH8,ACADM,ASIC2,CLK4,NCKAP5,CSMD3,PWWP2A,KIAA1211,ADORA3,KIDINS220,SLC44A5,HECW2,OSBPL1A,TXNDC16,ZNF578,HFM1,ABCD2,FAM135A,AMPD3,LRCH2,PPFIA2,MIER1,TMEM263,ASPA,CHRD,ATP2B3,ZNF583,RNF182,DPY19L3,DST,MTMR2,IL33,CACNB2,PTBP2,PRC1,KRIT1,CD38,C1orf52,CDC27,CDC42,LRRFIP1,MAGI1,CDO1,CFL2,SOCS6,CHM,CHN2,CASC2,MS4A7,SYNPR,NRXN3,CLCN4,QKI,HECTD1,COL4A5,SLC4A8,AHCTF1,ACBD5,NECTIN3,SLC35F1,PREPL,CREM,HAPLN1,RNF14,ANKRD44,FEZ1,OSBPL3,SUSD5,ATRNL1,VCAN,SLITRK5,GREB1,CCDC144A,HDAC9,RIPOR2,ARHGAP24,KCTD8,GIT2,DCC,ELMSAN1,DNAJC6,ZNF804A,ZEB2,ZBTB24,HEPH,MYEF2,DDX46,CHRDL1,USP3,DMTF1,DNM1L,ABCC9,GOLT1B,E2F5,EBF1,SYT15,PHF20L1,KCTD3,EIF4G2,PLEKHA1,C8orf37,DCTN4,EPB41L2,EPHA5,SRRM1,EPS8,RRAGB,EXTL2,F8,TESK2,KIAA1109,FGF12,FOXG1,SEMA4D,ATP13A4,SGIP1,C2orf88,SMC2,UFM1,PDLIM5,CAMKK2,ZNF605,KHDRBS3,STAU2,OGA,GABRA2,CHL1,AHCYL1,GART,KIAA1841,GDF9,PPARGC1A,ZNF276,GLS,DCLK2,TDRKH,STON1,EML4,PRDM5,LINC01551,GYG1,UBE2QL1,TNFAIP8L3,SHISA6,MSL1,FAM95B1,ZNF181,C5orf24,RBPJ,JAK1,KCNK1,KCNMA1,HECTD2,NCOA7,MAOB,MAP2,MARK1,MBNL1,SYT9,MDM4,MEIS1,SRSF12,KCTD6,CD200,NAP1L1,ZC3H12B,NDUFA5,NEFH,NEK1,NF1,NOVA1,NUMA1,OMG,CLDN11,ENPP2,BEST3,PIK3C2A,A2ML1,GPSM2,SH3KBP1,DRAM2,PPP2R5E,PPP3CA,SLC26A11,PTCH1,TMEM260,SH3TC2,ZCWPW1,RASGRF1,KHDRBS2,SLC6A15,ZYG11B,RET,FIGN,RGS7,RNF220,CARF,ROBO2,TMEM100,FBXW7,SPIN3,ABCA11P,RTKN,ZNF568,NCBP3,SEMA6D,ATXN2,SCN3A,FAM19A1,SCN8A,SEC14L1,MRAS,TRA2B,ITSN1,CHD9,FNDC3A,FHOD3,SYBU,DZIP1,SEPHS1,SLC8A3,SLC12A2,ATF7IP,ZKSCAN3,SMARCA4,RCOR3,LIMCH1,RIMS1,FAM126B,SON,TRERF1,SOX5,CDK19,TSPYL2,RBM26,TROVE2,COLGALT2,ELOVL4,DIP2A,FAM168A,VAMP1,VPS13A,SYT1,ANKRD12,TCEA1,EHBP1,ZEB1,WDR7,AZIN2,SYNE1,RALYL,FRYL,ITGB3BP,C5orf64,NPL,TSC1,RFTN2,PRR18,CADM1,PITPNB,FLRT2,BCL2L13,MTCH1,BEST1,TBC1D15,ZIC3,ZNF711,ZNF708,ZNF19,KCNT2,ZNF540,CELF4,REEP1,MEIS3,SLC30A4,CADM2,STOX2,MDH1B,PCDH15,FZD3,ST7,FBXO36,TRAM2-AS1,SLC39A12,NETO2,RNF146,SLC4A10" MicroRNA hsa-miR-586:PITA hsa-miR-586:PITA_TOP PITA 4.71E-108 2.65E-104 3.30E-107 3.04E-106 192 539 "CSMD3,FMNL2,KLHL32,GPR158,HECW2,PCDH19,ALCAM,ABCD2,CDC42BPA,LRCH2,ANK3,GPAM,PPP4R4,NCOA1,DDX3Y,ATP2A2,ZNF583,JAZF1,SGCE,CABP7,CALM1,CAMK2G,TMEM257,SEPT7,REPS2,ZMYM4,LGI1,FOXN3,SYNPR,NRXN3,CLTC,MAP4K4,IQCK,LETMD1,SLC4A7,PREPL,GDA,CS,SEC24C,CSNK1G3,ATRNL1,ERC2,CTNND2,HDAC4,ZFYVE16,RIMS3,DGKB,SCRN1,C8orf34,ZEB2,FBXO25,SPOCK3,WDR20,DLG2,DLG3,HS3ST4,NR1D2,CPEB2,RCAN1,GOLT1B,RBM12,MBNL2,EMX2,NCALD,ACSL4,ATP8A1,SEC24B,OLFM1,MEX3B,AFF2,TACC2,PDLIM5,FUT9,FYN,MSTN,PCDH17,KDM2B,HTATSF1,FERMT2,GPM6A,PCLO,GRM7,ADAMTS6,MAP4K5,BACH2,HLF,NEGR1,IGF1,IGSF1,KCNA1,KCNA4,KCND2,KCNK1,KCNQ3,TTYH2,MARK1,MBD1,MBNL1,LDLRAD3,MEIS2,KITLG,NEFM,NEUROD1,NFIX,CNOT4,NPY,HCN1,GPR137C,PDE4B,PDE4D,OLA1,SERPINE2,PIK3R1,XRN1,STRN3,LRP12,PPP3CA,PPP3CB,SNRK,PID1,BSDC1,RDX,SLC6A15,UBR7,PRIMA1,RIC8B,RAVER2,CARF,ROBO2,RORB,MRAP2,FBXW7,RTN1,AMER2,CSRNP3,SCN2A,SCN3A,CASC3,SFPQ,WDR47,PKNOX2,CCDC88A,CPEB4,SORCS3,SOX1,SOX11,POGZ,EPB41L3,ERBIN,STXBP1,NECAB1,SYT11,VPS13A,PLCB1,SYT4,CAMTA1,ADGRL3,TCF4,SATB2,TCF7,RPGRIP1L,TCF12,WASHC4,FRYL,AHCYL2,TEK,AKTIP,SLC44A1,TLL2,R3HDM1,TNS1,RBFOX2,TPM3,ZNF384,TRPC3,KCNE5,CADM1,UBE2H,SLAIN1,TBC1D15,NSD2,ZIC2,ZNF711,DPYSL5,CA10,RNF103,SLC17A6,RGS7BP,GOPC,RTN4,HNRNPA3,SLC4A10" MicroRNA hsa-miR-3130-5p:mirSVR_lowEffct hsa-miR-3130-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.42E-108 3.04E-104 3.78E-107 3.49E-106 287 1235 "SDE2,ARID1A,GALNT16,SLC24A4,GPR158,KCTD16,OSBPL6,ARHGAP20,FAM135A,DPP10,ANK3,APC,EPB41L5,GPAM,LRRC4C,TNRC6C,TMEFF1,NUMB,ATP1B3,ATP2A2,SLC2A11,SEC11C,SYNJ1,CACNA1G,KALRN,NGB,CAST,METTL6,CERS5,USP6,MTMR7,CBFA2T2,REPS2,LRRFIP1,DIS3L,CHN1,JAM2,TPP1,TJP2,ARHGEF6,IQCK,WHRN,SLC4A7,IFFO1,CNRIP1,MFSD4A,PLCXD3,GREB1,CCDC144A,HDAC9,KATNAL2,ARMCX4,C8orf34,MYEF2,TIAM2,GSDME,GUCD1,SMG7,RABGAP1L,CCDC3,GRIN3A,DYNC1I1,SLC25A18,ACOT8,MAMLD1,E2F5,ANKRD46,HEYL,SEMA3D,FRY,GPR61,KMT5B,RASA4,EPB41,RCAN2,GPHN,EFS,CDHR1,VPS26C,RTN3,ANKMY1,F3,CLVS1,DLC1,TOMM40L,TESK2,KIAA1109,SUCO,MEX3B,IP6K2,AGAP2,TPK1,DACH2,NSG1,DOT1L,ABLIM2,GABRG1,HBS1L,RAPGEF6,ZNF274,ATP8A2,ALDH1L1,USP19,GGTA1P,MALT1,GJB1,TXNL4A,TCERG1,DBF4,GLYR1,MSL3,WDFY3-AS2,PRUNE2,FUT10,MCHR1,ATP2B1-AS1,PLCD4,GRM7,LINC00839,LINC01551,LINGO1,FAM107A,HPS5,FRMD5,FRMD3,TNFAIP8L3,GABARAPL2,HSF2,EID2B,IDH3B,ZNF181,RAB41,C2orf72,IL11RA,METTL21A,GPR62,KCNK2,SYTL4,NCOA7,AQP11,CHST6,ADAM11,MDFI,MEIS1,KITLG,AFF1,MOG,SAMD5,JAKMIP3,LYRM9,MYO7A,HNRNPM,SFR1,NELL2,NME4,NTRK3,OGG1,OPA1,PCSK5,PDE4D,OLA1,NLGN3,SSH1,CAMKV,ZNF655,NLE1,TRHDE,RC3H2,ING3,SH3KBP1,PRKAB2,WBP1L,MDGA2,PIGG,BDNF-AS,PTPRB,OCIAD1,PTPRE,USP47,PLEKHB2,ZNF793,RASGRF1,ZDHHC14,RGS12,RLBP1,SLC25A36,PBRM1,MYH14,CARF,CYB561D1,RPL15,LGR4,WLS,ZNF354C,DGLUCY,SCN8A,TNFRSF19,ASIC4,ELMOD1,SOX6,HSPA4L,ITSN1,FBXO11,ST6GAL1,ST3GAL3,PEX26,KANSL3,PKNOX2,LRRC55,SCMH1,NAXD,KIF13A,SNRPN,FAM126B,UNC80,FAM219A,SON,PDZD2,SOX1,KDM4C,KIF1B,ZBTB43,ZNF302,ZC4H2,RGL1,NSFL1C,VPS13A,ANKRD28,POPDC3,ROBO3,EXOC7,CNTN2,FBXW11,ANO4,TBX15,TPCN2,RPGRIP1L,CLASP1,WDR7,SYNE1,DOCK9,AKNA,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,FAM200B,LEFTY2,AP4E1,CDH22,TIE1,TLR4,RASD2,TPM3,IL34,SMUG1,TSC1,ZKSCAN5,TUBB1,RPRM,FAM155A,UBE3A,USP1,VAV2,VLDLR,WIPF1,ZIC2,ZNF28,ZNF70,FMN2,SPIRE1,SYNC,DHX33,SLC38A1,PRDM10,URM1,PPP1R3F,KCNAB1,UBE3B,ADAMTSL3,SENP7,JPH3" MicroRNA hsa-miR-592:mirSVR_highEffct hsa-miR-592:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-107 6.65E-104 8.26E-107 7.61E-106 271 1107 "TTYH1,ACADM,TMEM132B,GALNT16,SORCS1,ERMN,PWWP2A,GPR158,PLA2G6,LRRC7,ALCAM,DPP10,ANK3,MAP4K3,MAGEE2,LRRC4C,USP37,TMEFF1,ZFYVE28,NUMB,STX16,ATP2B1,DPY19L3,ADAM23,TTLL9,BACH1,BARD1,NRP2,ARHGEF7,CALB1,THSD7A,KALRN,SLC25A14,SPAG9,CCKBR,TMEM257,CDH2,MAGI1,CHGB,CHN2,CASC2,NDST3,NRXN3,FBXO7,TJP2,CNR1,AKAP7,AKAP6,SUMF2,ZFP28,CNRIP1,CP,CRMP1,HAPLN1,FEZ2,MICAL2,NCAN,ERC2,ARHGEF4,NRSN1,CX3CR1,CCDC144A,TCAF1,SNPH,LONRF1,DGKB,DAPK1,IP6K1,PABPC5,ARMCX4,ZEB2,KIAA0753,BLOC1S6,G3BP2,RABGAP1L,CPEB2,DMTF1,SLC25A18,ECM2,DYRK1A,ABCC9,E2F6,SNX29,SEMA3D,FSD1L,AASS,EML1,C8orf37,EPHA5,MRPL37,ETV1,F8,ARMCX1,CLVS1,FABP7,CORO2B,FGF12,CAP2,NELFCD,PDLIM5,AP4B1,GAB1,HRASLS5,GCNT2,MSTN,ADAM28,MMADHC,KIRREL3,GK,LUZP2,RAB40B,GNAL,GPD2,PRUNE2,GPM6B,PCLO,RAPGEF4,RAPGEF1,GRM7,RNF165,C1orf94,ARHGAP36,ELOVL5,USP51,TCEAL6,LIX1,IL6ST,JAK1,KCNA2,HECTD2,MAP4,MBNL1,LRP1B,POC1B,MOV10,CD200,MRPL42,ZNF92,MX1,MYCN,NDUFA5,NEK1,VWA2,NOVA1,NRCAM,GLIPR1L2,PAX6,PBX1,PCDH9,PDE1C,PDE3B,PDE4D,CDK14,A2ML1,GPSM2,PLIN1,ING3,POLR2F,CRLS1,PPP2R5E,RANBP3L,PKN2,MAPK9,GRAMD1C,VPS13C,PTHLH,TMEM260,PTPRD,PEX5,MARCH1,USP47,SUSD4,RASGRF2,ARID4A,SLC6A15,ZMAT4,REV3L,PRRT2,SEC61A2,RNF220,ZFHX4,EXD2,ROBO1,ELP2,NEK11,PTGR2,WLS,CLIP1,NCBP3,LINC00461,SCP2,ELMOD1,SLC30A10,FOXRED1,ZFP30,SH3GL3,PPM1E,MAGI3,ST6GAL1,SEC31A,ZNF430,SLC8A1,SLC12A2,SPHKAP,SMARCE1,RCOR3,ANKRD36,SNAP25,SNCA,CMTR2,FAM126B,ZCCHC24,BDP1,DOK5,SP2,KIF1B,LMO3,C11orf87,SRPK2,SAMSN1,KANK1,RHBDL3,ARHGEF9,PLCB1,SYPL1,ANKRD28,TAL1,UNC5D,ADGRL3,ANO4,ATMIN,ACSL6,RPGRIP1L,SYNE1,FRYL,TIAM1,MTMR14,TJP1,ASXL3,NR2E1,ERCC6L2,TPM3,PRMT8,PPIL6,RUSC1,UGT8,WIPF1,CLDND1,GUSBP1,ZNF708,KCNT2,FMN2,ANKS1B,PLPPR5,ZXDA,EMSY,STMN4,STOX2,RNF103,HPS4,FIP1L1,LINC00632,WNK3,FAM13C,ST7,SMIM8,CERS6,ADAMTSL3,IFT88,SPATA13,SENP7" MicroRNA hsa-miR-500b:mirSVR_lowEffct hsa-miR-500b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-107 9.81E-104 1.22E-106 1.12E-105 329 1609 "KCNH8,ABR,ABHD6,NCKAP5,CSMD2,GALNT16,TMCC3,GALNT13,ESYT2,KIDINS220,AP2A2,MTUS1,CC2D2A,ADGRF5,CEP126,LRCH2,PPFIA1,EPB41L5,DGKZ,CACHD1,APP,SHTN1,ARNTL,ZBTB10,TMEM108,CHID1,ATM,EIF4G3,ATP6V0A1,BACH1,BCHE,MIR9-3HG,PROM1,CDK5R1,FUBP1,NIPA1,CA8,KALRN,CAMK2A,VSTM2A,CBS,CCNH,RGN,INA,CDC27,MAGI1,IGFN1,NUMBL,CHGA,CASC2,MS4A7,SYNPR,B4GALT6,ZFYVE9,CLCN3,CLTA,QKI,NIPBL,COL4A5,COX4I1,BAG4,MYRIP,ZNF521,SEC31B,C2CD2,CREB5,HAPLN1,ATRNL1,RUBCN,CCDC144A,NOS1AP,FGFR1OP2,DCAF8,MATR3,AIF1L,DNAJC6,FBXO25,SV2B,NTM,GRIN3A,DMD,NR1D2,DTNA,DNAJB6,E2F5,E2F6,USH1C,FCF1,FRY,EFNA3,RBM12,PHF20L1,MBNL2,KMT5B,ABI2,AASS,PLEKHA1,PCOLCE2,PAN3,RCAN2,ERCC2,RTN3,ANKMY1,MRVI1,F5,REEP2,ARMCX1,FABP7,RACK1,CEP78,SEC24B,FER,FGF1,FGF12,POLK,UBE2E3,MEX3B,PCYOX1,VTI1B,SYNCRIP,FLT1,C2orf88,WDR83,SORBS1,APOPT1,FAM49B,ARFGAP2,ATP6V1H,CELF1,MSANTD4,PHYHIPL,ZMAT1,DKK3,DENND2A,IP6K3,DISC1,DNER,NEU3,GFRA2,MALT1,GJB1,GLI2,GLS,ZNF638,GPR12,EML4,STMN2,GRIA2,GRIA4,GRIK2,PRDM5,GRM7,RNF165,AP4S1,ATOH8,MAEL,HAS2,ATXN2L,HPSE2,HNF4G,DHX35,MSL1,IDH3B,RBPJ,NIM1K,LIX1,ZNF385B,KCNC2,KCNK1,KIF5C,KTN1,LAMP2,NCOA7,MATN2,MBNL1,SYT9,TM6SF1,LRP1B,MEIS1,KCTD6,MIA2,WDR49,SESN3,BLOC1S2,MYO7A,NEFH,NEK1,NFE2L2,NOVA1,CLEC9A,SLC11A2,NUCB2,GLIPR1L2,CNTN3,DPY19L2P2,PDE3A,GPR173,SERPINI1,FAM218A,KCTD15,HMGCLL1,PLXNB1,PMP2,PRRX1,ING3,SPATA6,RETREG2,FAT3,NXPH1,DRAM2,PPP3CB,DCHS2,SAMD9,ZIK1,PTPRG,PTPRZ1,TMEM145,TUG1,PPP2R3C,FAM66C,SH3TC2,ENOX1,OXR1,RASGRF2,RBBP8,KHDRBS2,TRIM68,RET,FIGN,RFX3,RFX5,RIC8B,TMEM100,NEK11,ZC3H14,PRR5L,TCP11L1,LRRK2,CNTNAP3,MEG3,ABCA11P,FAM182A,SCP2,TRIM46,SCAF8,KIF21A,SH3GL3,FERMT1,DZIP1,URGCP,SLC6A1,PKNOX2,BTBD7,CPEB4,SMARCE1,IFT122,CABCOCO1,SOX2,BDP1,SP4,CLUAP1,ENKUR,MYCBP2,IDI2-AS1,DBNDD2,SPTAN1,CDK19,TSPYL2,SPART,SRPK2,POGZ,THSD1,ELOVL4,ADHFE1,ARHGEF9,VPS13A,SYN1,SYN2,TAC3,KAZN,CAMTA1,CAMSAP2,UNC5D,EHBP1,DMXL2,SATB2,RPGRIP1L,FAM200B,PMS2CL,CRB1,MTMR14,KCTD2,R3HDM1,C9orf85,WBP2,PRMT8,TRIO,TRPS1,FNDC5,RFTN2,CADM1,UBE3A,SLAIN1,BCL2L13,VAV1,RICTOR,XPO1,ZIC2,TRIM9,ATP6V0E2,TMEM237,ANKS1B,SMARCAD1,STOX2,RNF103,ADAMTS9,FAM47E,EPM2A,FAM13C,FZD3,HNRNPA3,ZNF248,VANGL2,MSRB3,KLHDC1,IFT88,NETO1,FAM198A,SPATA13" MicroRNA hsa-miR-4259:mirSVR_lowEffct hsa-miR-4259:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.85E-107 1.04E-103 1.29E-106 1.19E-105 315 1483 "CPNE2,RALGAPA1,TTYH1,DGCR6,ASIC1,CLK4,SLC25A25,ADCY2,ADD2,BRAP,SLC12A5,GRAMD1B,KIAA1211,FAHD2CP,KIDINS220,DPY19L2P4,CC2D2A,ADGRF5,PCDH10,ZNF687,DPP10,PI16,APLP1,GPAM,PHYHD1,VAT1L,PRX,ARHGAP5,ARNTL,CDK13,ASPH,TMEM108,SLC2A11,ATP6V0A1,MYOM1,TTLL9,ADAM15,SEC11C,BCL2L2,DCAF5,FGF17,BMP7,SYNJ1,CASTOR3,MTMR3,CALB2,CAMK2G,CAST,METTL6,INA,ENTPD6,REPS2,MAGI1,SRSF11,ASIC3,CHM,LSMEM2,EPS15L1,CPNE6,CLU,FAM19A5,NIPBL,CNN3,ARHGEF6,PCYT1B,AKAP6,LETMD1,SMARCAL1,CRMP1,NCOR1,TENM4,CSF1R,SEC24C,SDC3,ERC2,PHF14,NRSN1,PPP6R2,FAM131B,CX3CR1,TCAF1,ZNF337,KCTD8,DGKB,ZEB2,B3GAT3,MAGI2,RABGAP1L,ARNT2,GRIN3A,DNM1,HS3ST2,USP3,CPEB2,FAM57B,DRD1,GNE,DNM1L,EDN1,PHC2,FCF1,HEYL,YAF2,SH3GLB1,CELSR3,EGFR,MRO,ANKRD13B,RABEPK,NCALD,IGSF6,MRPL10,ANKMY1,SIRPB1,MRVI1,FAM198B,ACSL4,TUBB4A,TESK2,FGF11,POLK,SYNCRIP,NELFCD,FAM49B,BRSK1,ZNF512,GABRA1,GABRA5,GAD2,BRPF3,NCKAP1,ATP8A2,ALDH1L1,CYP46A1,GGT7,GHR,MALT1,MSL3,GNAS,GPT2,GPM6A,GPM6B,TDRKH,PLCD4,SERP2,GRIN2D,GRM2,RNF165,ZBTB45,AP4S1,FAM107A,SLC2A6,LINC01102,SYNPO,ZDHHC15,IRF8,SOWAHA,DISP2,SCRT2,NME9,ITGA7,ITGAV,KCNC1,KCNJ10,KIF5A,MAP6,MBD1,MOBP,MSR1,MT1M,MTTP,HS6ST3,MYO7A,P2RY13,NEK1,NFE2L2,VWA2,NOVA1,NOVA2,HCN1,SNTG1,PDGFRA,SSH1,CCSER2,PLCB2,PLXNB3,NECAB2,PCDHB17P,PPP2R5E,NKAIN4,PRKCG,MAPK4,EPDR1,MAPK7,SIDT1,OCIAD1,FAM120C,RAB3A,RAD51D,FAM184A,RBBP6,ZDHHC14,MSANTD2,SLC6A15,PRRT2,RFX4,RFX5,RGS12,SLC25A36,RIC8B,CARF,PNMA8A,ROBO2,SNX22,NEK11,EPHA10,SPIN3,GLDN,LGR4,ABCA11P,ZNF331,AP1AR,SEMA6D,CSRNP3,SCN2B,SCN8A,SCP2,SLC30A10,COPZ1,FNDC3A,CCDC92,ST3GAL3,DZIP1,SLC6A8,SLC8A2,SLC8A3,ARHGEF40,SLC11A1,NAPB,SPHKAP,EPC1,MAST1,IGSF9B,LIMCH1,SNCA,CMTR2,KDM4B,SCN3B,DOP1A,SON,SOX10,ZSWIM8,CAND2,HECW1,PEG10,KIF1B,RAP1GAP2,DDN,ATP10B,CLSTN2,COLGALT2,ITPRID2,STAC2,STXBP1,FAM168A,NECAB1,SYP,POPDC3,KAZN,MLST8,WWC1,VWA3A,EHBP1,CUX2,FAM189A1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,AP4E1,TGFBR3,THRA,ASXL3,TPM4,RGMB,SMUG1,AMACR,TRPC3,GORASP1,OSBP2,BEST1,WIPF1,CLDND1,XRCC4,NDRG4,SLC26A10,ZNF177,ZNF195,SLC30A4,MFF,DNALI1,ADAMTS9,TMEM178A,NAV3,WIPF2,WNK3,C12orf4,DOCK8,KAT6A,FBXO36" MicroRNA hsa-miR-150*:mirSVR_highEffct hsa-miR-150*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.04E-107 1.15E-103 1.42E-106 1.31E-105 251 952 "KCNH8,GRAMD1B,PWWP2A,OLMALINC,HECW2,TXNDC16,ADGRF5,CEP126,ABCD2,FAM135A,ALS2,TMEFF1,CADPS,ASPH,ATP2B3,DPY19L3,ADAM23,KSR1,SYNJ2,ARHGEF7,CA8,KRIT1,METTL6,SLC16A4,ENTPD6,DGKI,ARHGEF2,CDC27,CDH2,CDH8,LGI1,DLGAP1,SRSF11,PPT2,CLCN3,ABCG2,QKI,CNTN1,COL9A1,LETMD1,SLC4A8,COX4I1,ZNF521,HS3ST5,CP,CS,SNCAIP,SEC24C,ARHGEF10,SUSD5,DOCK4,FGFR1OP2,ARHGAP24,FRMPD4,LONRF1,DAPK1,ZEB2,ZBTB24,FBXL5,ALKBH8,PLPPR4,SV2B,NTM,DLG2,DMTF1,ABI1,DNAJB6,DYRK1A,EGR3,ELAVL4,STARD3NL,CALCRL,GPHN,NCALD,CLVS1,FAM198B,ZNF461,TOMM40L,FER,PRKAG2,POLK,CAP2,SGIP1,NBEA,PDLIM5,CELF1,ZNF512,GABRA1,GABRA2,GAD1,ZMYND11,ARPP21,GATM,ARFIP1,ADAM28,PCDH17,COPS8,ZNF638,POLL,GNAL,LOXL3,GNAS,CNTRL,RABL2A,GUCY1A2,MAEL,MIER3,HNRNPK,ZDHHC15,SMAP1,ZIC5,IL12A,ZNF385B,LRRTM3,LRRTM1,ITGAM,KCND2,KLRC3,KPNA5,IPO5,STXBP5,LAMP2,INSYN2,SYTL4,HECTD2,C2orf80,MITF,AFDN,MN1,JAKMIP3,ZNF92,MXI1,NAP1L1,NCAM1,GPR88,OLR1,OPHN1,LOC100128398,OXTR,GPR137C,ZNF827,PCSK5,PDE4D,ENPP2,PDPK1,FAM98B,PIK3C2A,XRN1,FAM216A,JAKMIP1,STRN3,RC3H2,EPB41L4B,PPP2R5C,PPP2R5E,PRKCB,SIDT1,PTHLH,PTK2,PTPRN,PTPRO,ENOX1,OXR1,MSANTD2,REV3L,RFX5,RGS3,KCTD17,SUGCT,CARF,TMEM206,ELP2,PCMTD2,NEK11,MCMBP,RYR3,SARS,SCN2A,SCN3A,LRRTM4,FAM19A1,SCN8A,SEC14L1,SFPQ,FBXO11,FHOD3,NUBPL,EPN2,CCDC88A,ELMO2,SLC22A4,ZFP1,OGDHL,INTS9,MBD5,SNRPN,FAM126B,SON,NPAS3,TROVE2,SSTR1,CEP68,TTBK2,GANAB,SEPT3,STXBP1,NECAB1,FBXW11,KLHL4,TCEA1,ACSL6,SYNE1,DOCK9,SIK3,TEK,DICER1-AS1,ITGB3BP,TIAM1,HEY2,TMPO,BEX4,CSMD1,TPD52L2,RGMB,PRMT8,UBE3A,SLAIN1,PCDH20,ZIC1,ZNF708,ZNF23,KCNT2,TRIM9,ANKS1B,UPF3A,CADM2,ADAMTS9,MDH1B,GAL3ST3,NAV3,SLC17A6,FAM13C,DOCK8,PAK5,JMJD1C,TRAM2-AS1,ZNF248,RNF170,IFT88,NETO2,SLC4A10" MicroRNA hsa-miR-200a:PITA hsa-miR-200a:PITA_TOP PITA 2.73E-107 1.53E-103 1.89E-106 1.74E-105 205 626 "CSMD3,ADD3,PCDH19,RTL9,OSBPL8,SEMA6A,AMPD2,OGT,APBB2,MIER1,TMEFF1,ARNTL,CDK13,ASTN1,STX16,ST3GAL5,CACNA1I,LDLRAD4,CANX,SYT6,SPAG9,SEPT7,CDH10,CCPG1,CFL2,FOXN3,CLCN4,NRXN1,QKI,HECTD1,MAP4K4,MYRIP,CLOCK,CDC42BPB,CSNK1E,CSNK1G3,ATRNL1,NCAN,ERC2,APPL1,CTNND2,KIAA0408,DOCK4,HDAC4,TM9SF4,DAPK1,ARMCX2,YTHDC1,ZEB2,CEP170,LYPD1,SMG7,SNAP91,DLG3,GRIN3A,CPEB2,ATL1,RBM12,YAF2,ELAVL2,ELAVL4,STX2,ZIC4,DLC1,ATP8A1,TESK2,FGF13,AFF2,SMC2,MSANTD4,PHYHIPL,MEGF10,GAB1,ATP8A2,SRCAP,PPARGC1A,TCERG1,GLS,KDM2B,GPD1,TMEM121B,PCLO,GRB10,ADAMTS8,GRIN2D,KIF3A,KLF12,MIER3,HLF,ACOT7,HMGB1,LRRTM3,IPO5,STXBP5,TTYH2,MARK1,MBNL1,CHIC1,MN1,CCDC80,MDGA1,MYO5A,NEXMIF,NAP1L3,NCAM1,NPTX1,NRCAM,HCN1,GPR137C,PCDH8,PCDH9,CCSER2,PLCL1,EPN1,TRHDE,SCHIP1,FAT3,POU3F2,MED1,PPP2R2B,PPP2R5E,VSTM2L,GDPD1,SNRK,PTCH1,PTPRD,PTPRG,KHDRBS2,ZYG11B,TTLL7,RAVER2,SNX22,ATXN1,ATXN7,SCN2A,SCN2B,SCP2,ELMOD1,SFPQ,SUPT20H,HSPA4L,ITSN1,PPM1E,CPEB3,DOCK10,CHD9,ST3GAL3,SLC6A9,SLC20A2,TET1,CPEB4,RCOR3,IGSF9B,RIMS1,MBD5,PDZD2,MYT1L,SOX5,ZCCHC24,SOX11,SP4,KIF1B,NFASC,LMO3,TAB2,CLASP2,ITPRID2,SEPT8,TTBK2,STXBP1,KLHL7,NECAB1,SYT4,CAMSAP2,TCF4,TCF12,AZIN2,TEX15,SIRT1,ZFPM2,TIAM1,TJP1,ZFP91,KAT6B,TNS1,NR2C2,TSC1,CADM1,UBE2H,UBE3A,PITPNB,WIPF1,NSD2,CLDND1,ZNF711,ZNF24,WNK1,EMSY,SNX27,SLC17A6,ZNF248,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-141:PITA hsa-miR-141:PITA_TOP PITA 2.73E-107 1.53E-103 1.89E-106 1.74E-105 205 626 "CSMD3,ADD3,PCDH19,RTL9,OSBPL8,SEMA6A,AMPD2,OGT,APBB2,MIER1,TMEFF1,ARNTL,CDK13,ASTN1,STX16,ST3GAL5,CACNA1I,LDLRAD4,CANX,SYT6,SPAG9,SEPT7,CDH10,CCPG1,CFL2,FOXN3,CLCN4,NRXN1,QKI,HECTD1,MAP4K4,MYRIP,CLOCK,CDC42BPB,CSNK1E,CSNK1G3,ATRNL1,NCAN,ERC2,APPL1,CTNND2,KIAA0408,DOCK4,HDAC4,TM9SF4,DAPK1,ARMCX2,YTHDC1,ZEB2,CEP170,LYPD1,SMG7,SNAP91,DLG3,GRIN3A,CPEB2,ATL1,RBM12,YAF2,ELAVL2,ELAVL4,STX2,ZIC4,DLC1,ATP8A1,TESK2,FGF13,AFF2,SMC2,MSANTD4,PHYHIPL,MEGF10,GAB1,ATP8A2,SRCAP,PPARGC1A,TCERG1,GLS,KDM2B,GPD1,TMEM121B,PCLO,GRB10,ADAMTS8,GRIN2D,KIF3A,KLF12,MIER3,HLF,ACOT7,HMGB1,LRRTM3,IPO5,STXBP5,TTYH2,MARK1,MBNL1,CHIC1,MN1,CCDC80,MDGA1,MYO5A,NEXMIF,NAP1L3,NCAM1,NPTX1,NRCAM,HCN1,GPR137C,PCDH8,PCDH9,CCSER2,PLCL1,EPN1,TRHDE,SCHIP1,FAT3,POU3F2,MED1,PPP2R2B,PPP2R5E,VSTM2L,GDPD1,SNRK,PTCH1,PTPRD,PTPRG,KHDRBS2,ZYG11B,TTLL7,RAVER2,SNX22,ATXN1,ATXN7,SCN2A,SCN2B,SCP2,ELMOD1,SFPQ,SUPT20H,HSPA4L,ITSN1,PPM1E,CPEB3,DOCK10,CHD9,ST3GAL3,SLC6A9,SLC20A2,TET1,CPEB4,RCOR3,IGSF9B,RIMS1,MBD5,PDZD2,MYT1L,SOX5,ZCCHC24,SOX11,SP4,KIF1B,NFASC,LMO3,TAB2,CLASP2,ITPRID2,SEPT8,TTBK2,STXBP1,KLHL7,NECAB1,SYT4,CAMSAP2,TCF4,TCF12,AZIN2,TEX15,SIRT1,ZFPM2,TIAM1,TJP1,ZFP91,KAT6B,TNS1,NR2C2,TSC1,CADM1,UBE2H,UBE3A,PITPNB,WIPF1,NSD2,CLDND1,ZNF711,ZNF24,WNK1,EMSY,SNX27,SLC17A6,ZNF248,MSRB3,NETO2,ST8SIA2,SENP7" MicroRNA hsa-miR-19b:PITA hsa-miR-19b:PITA_TOP PITA 2.92E-107 1.64E-103 2.02E-106 1.86E-105 222 741 "ABR,ASIC1,ACTN1,GPR158,HECW2,SRPX,PITPNM2,CDC42BPA,LRCH2,MAP4K3,ANXA7,API5,SHTN1,ARHGAP5,CDK13,STK33,CAPRIN2,ZBTB10,CCAR2,DDX3Y,ATP2B2,NOL4,NRP2,ST3GAL5,JAZF1,BSN,THSD7A,CALM1,CAST,USP6,SEPT7,ZMYM4,EVI5L,ZNF445,CCPG1,CFL2,PLAA,CLTC,QKI,CNGA3,CNTFR,BTF3L4,ACBD5,ZNF521,SLC35F1,CLOCK,CRMP1,GDA,CS,MICAL2,CHD5,SOCS5,APPL1,PPP6R2,SNPH,DCAF8,HDAC4,LONRF1,MAML1,DBN1,ZNF804A,ZEB2,CEP170,MAGI2,SV2A,SRGAP3,G3BP2,DLG2,DSCAM,ARRDC4,ST8SIA3,HIPK3,MBNL2,EGR3,PLXNC1,EMX2,ERBB4,NCALD,ETV1,WAC,ACSL4,PTK2B,SCML2,DLC1,TESK2,MED12L,OLFM1,CAMSAP1,FOXF2,FLNC,NBEA,NPTN,FUT9,CAB39,GAD2,ARFIP1,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,KIF3A,SOX21,MIER3,HLF,ELOVL5,IGF1,C5orf24,ZIC5,KCNA4,KCND2,KCNK2,KIT,INSYN2,ARHGAP12,MBNL1,CHIC1,MID1,AFF1,MYCN,NEXMIF,NEUROD1,TBC1D25,PDE1C,PFKFB3,PIK3C2A,CCSER2,LRP12,TNPO2,FAT3,POU3F2,PTPA,PPP2R5E,VSTM2L,PSD,WBP1L,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,ZYG11B,SEC61A2,ROBO2,RIMKLA,CLIP1,RTN1,ATXN1,SCN3A,SCN4B,SOX6,SGK1,ITSN1,FAM102A,PPP1R9A,CPEB3,DOCK10,FNDC3A,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,CPEB4,RCOR3,MYT1L,SOX5,CDK19,SMOC1,RGL1,FAM168A,SYT11,C3orf70,PLCB1,ARC,SYN2,SYT1,ATP11A,ANKRD12,CAMTA1,CAMSAP2,FBXW11,EHBP1,TCF4,SIN3B,DMXL2,TRIM2,ARHGEF12,DICER1,ZFPM2,ZFP91,RIMBP2,TNFRSF1B,CSMD1,RBFOX2,WBP2,STXBP4,TRPS1,TSC1,TUB,FAM155A,SLAIN1,TOM1L2,ZBTB14,ZNF711,SLC26A10,SPHK2,REEP1,DPYSL5,WNK1,PMEPA1,MAP3K12,MFF,NAV3,SNX27,PDSS2,RGS7BP,PHTF2,FXR1,CBLN2" MicroRNA hsa-miR-19a:PITA hsa-miR-19a:PITA_TOP PITA 2.92E-107 1.64E-103 2.02E-106 1.86E-105 222 741 "ABR,ASIC1,ACTN1,GPR158,HECW2,SRPX,PITPNM2,CDC42BPA,LRCH2,MAP4K3,ANXA7,API5,SHTN1,ARHGAP5,CDK13,STK33,CAPRIN2,ZBTB10,CCAR2,DDX3Y,ATP2B2,NOL4,NRP2,ST3GAL5,JAZF1,BSN,THSD7A,CALM1,CAST,USP6,SEPT7,ZMYM4,EVI5L,ZNF445,CCPG1,CFL2,PLAA,CLTC,QKI,CNGA3,CNTFR,BTF3L4,ACBD5,ZNF521,SLC35F1,CLOCK,CRMP1,GDA,CS,MICAL2,CHD5,SOCS5,APPL1,PPP6R2,SNPH,DCAF8,HDAC4,LONRF1,MAML1,DBN1,ZNF804A,ZEB2,CEP170,MAGI2,SV2A,SRGAP3,G3BP2,DLG2,DSCAM,ARRDC4,ST8SIA3,HIPK3,MBNL2,EGR3,PLXNC1,EMX2,ERBB4,NCALD,ETV1,WAC,ACSL4,PTK2B,SCML2,DLC1,TESK2,MED12L,OLFM1,CAMSAP1,FOXF2,FLNC,NBEA,NPTN,FUT9,CAB39,GAD2,ARFIP1,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,KIF3A,SOX21,MIER3,HLF,ELOVL5,IGF1,C5orf24,ZIC5,KCNA4,KCND2,KCNK2,KIT,INSYN2,ARHGAP12,MBNL1,CHIC1,MID1,AFF1,MYCN,NEXMIF,NEUROD1,TBC1D25,PDE1C,PFKFB3,PIK3C2A,CCSER2,LRP12,TNPO2,FAT3,POU3F2,PTPA,PPP2R5E,VSTM2L,PSD,WBP1L,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,ZYG11B,SEC61A2,ROBO2,RIMKLA,CLIP1,RTN1,ATXN1,SCN3A,SCN4B,SOX6,SGK1,ITSN1,FAM102A,PPP1R9A,CPEB3,DOCK10,FNDC3A,EPN2,WDR47,SLC6A8,CCDC88A,NAPB,CPEB4,RCOR3,MYT1L,SOX5,CDK19,SMOC1,RGL1,FAM168A,SYT11,C3orf70,PLCB1,ARC,SYN2,SYT1,ATP11A,ANKRD12,CAMTA1,CAMSAP2,FBXW11,EHBP1,TCF4,SIN3B,DMXL2,TRIM2,ARHGEF12,DICER1,ZFPM2,ZFP91,RIMBP2,TNFRSF1B,CSMD1,RBFOX2,WBP2,STXBP4,TRPS1,TSC1,TUB,FAM155A,SLAIN1,TOM1L2,ZBTB14,ZNF711,SLC26A10,SPHK2,REEP1,DPYSL5,WNK1,PMEPA1,MAP3K12,MFF,NAV3,SNX27,PDSS2,RGS7BP,PHTF2,FXR1,CBLN2" MicroRNA hsa-miR-4271:mirSVR_highEffct hsa-miR-4271:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.11E-107 1.75E-103 2.15E-106 1.98E-105 266 1071 "ABCF1,ASIC1,ACLY,EMILIN3,GPRIN1,ADCY6,ADRA1D,ADRB2,SNX32,CC2D2A,SMIM17,PI16,ALS2,SHROOM2,MIER1,ARNTL,ASPH,PCDHGB4,ATP6V0A1,MYOM1,TTLL9,TTC9B,SGCE,CA12,CAMK2B,TRIM41,VXN,SPAG9,AIFM1,CBFA2T2,LRBA,ARHGEF2,REPS2,ZMYM4,LARGE1,PLEKHB1,CASC2,CNOT8,NRXN3,PLAA,PPT2,TJP2,FADS2,ARHGEF6,AKAP7,SUMF2,IFFO1,SMARCAL1,ACBD5,IGDCC3,CP,FAM171B,SEC31B,PREPL,RNF14,HINFP,CLIP3,SNCAIP,CSF3R,DZIP3,PUM1,ST18,MYADM,ARHGAP24,PHYHIP,DGKB,DGCR5,SPOCK3,CDON,DPH1,DPP6,SLC25A18,DTNB,DUSP9,DYRK1A,SNX29,EDN1,FAM135B,PHC2,EFNA3,ELAVL2,BSCL2,TMEM35A,SRRM1,ERBB2,MRPL10,SIRPB1,F5,ACSL4,PTK2B,TAOK3,CORO2B,TESK2,PPP1R1B,GORAB,FER,FHL1,POLK,SMC2,PDLIM5,NPTN,ARFGAP2,ATP6V1H,ERGIC3,STAU2,HHIPL1,ZNF512,GABBR1,HRASLS5,GABRA3,GALNT15,B4GALNT1,JPH4,ARPP21,IGSF5,TUBA8,MMADHC,GLI2,TNRC6A,CCDC184,PLCD4,GRIK1,GRIK3,GSTM5,KAT7,LINGO1,FAM107A,CELF3,IGSF21,ATXN2L,ARHGAP36,HNMT,HSPA1L,CELF5,RBPJ,IL6R,ZNF678,ITGA7,KCNJ10,KCNMA1,MAT2A,SCAMP5,GIT1,MRPL42,NOVA1,DNHD1,NTRK3,NUMA1,IGSF11,PBX1,PCDHGC3,PCSK5,CDK18,BEST3,PFKFB2,TMEM38A,ST8SIA5,PURG,SEPT4,MBOAT7,PILRA,POLG,SH3KBP1,POLR2F,PPP3CC,PRKACB,PRKCG,MAPK10,HYDIN,DCHS2,BCAS3,GON4L,PTHLH,RAD52,RASGRF1,RASGRF2,ZDHHC14,GTDC1,LGI2,RPL15,TCP11L1,CNTNAP3,LGR4,RTKN,RXRG,NCBP3,LINC00461,ELMOD1,FOXRED1,ITSN1,SH3GL3,FNDC3A,R3HDM2,ST3GAL3,ZNF365,PPP4R3A,RUFY2,FAM214B,SLC6A1,KDM4D,RAB3GAP1,SIRT2,SLC9A5,SNRPN,UNC80,SON,WDTC1,KIF21B,ZNF423,SPTAN1,IQSEC2,DDN,NFASC,C11orf87,POGZ,NCDN,MPRIP,GANAB,SEPT3,PLCB1,SYN2,MMS19,DDHD2,DNMBP,SMG6,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB6,THRA,TIAM1,R3HDM1,SEZ6L,ZNF384,PRMT8,RUSC1,UGT8,BEST1,SF1,ZIC3,AGMO,SLC26A10,MKRN3,CELF4,MEIS3,CSDE1,ST7,KAT6A,CAMK1G,NUP214,JMJD1C,ZNF248,VANGL2,PIANP,PRRT4,JPH3" MicroRNA hsa-miR-4263:mirSVR_highEffct hsa-miR-4263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.64E-107 2.61E-103 3.20E-106 2.95E-105 287 1245 "ACADM,CLK4,NCKAP5,KDM5D,ARID1A,XKR4,FMNL2,ADCY8,ERMN,PLEKHH1,KIAA1211,ADRB2,MTUS1,KCTD16,OSBPL8,HFM1,LRRC7,FAM135A,ANK2,ANK3,LCORL,TMEM263,RGS20,PDE8B,NCOA1,RNF182,ADGRB3,SEC11C,CDK5R1,DST,C5,OSGIN2,RAB29,THSD7A,PTBP2,CAMK2G,SYT6,SEPT7,ZMYM4,TIGD7,CFL2,CASC2,SYNPR,B4GALT6,NRXN1,CLU,NIPBL,CNR1,BTF3L4,ABI3BP,RTTN,MYRIP,MFSD4A,ANKRD44,SNCAIP,ARHGEF10,CSNK1E,CSNK1G3,SUSD5,SIPA1L1,NCAN,SOCS5,FAM169A,DZIP3,GREB1,DCAF4,DOCK4,HDAC9,KATNAL2,ZFYVE16,KIAA0586,PABPC5,GIT2,ZEB2,SPOCK3,FAM107B,OLIG1,NR1D2,DMTF1,TOM1,DNAJB6,DNM1L,AASDH,WDPCP,EDN1,SEMA3D,EGR3,ELAVL4,ZNF549,RTN3,ADGRV1,CLVS1,FAM198B,SH3YL1,ACSL4,CEP78,ZNF589,IP6K2,SYNCRIP,NBEA,APOPT1,PDLIM5,ATP6V1H,TBR1,NRG3,OGA,STAG2,GABRA1,GABRG2,CAB39,DENND2A,RAPGEF6,ZNF234,NEK6,NCKAP1,ZNF559,DISC1,MYOZ2,GATM,ARFIP1,PPARGC1A,GLS,MSL3,KCNMB4,DCLK2,PRUNE2,RFFL,ATE1,GRM1,GRM7,LINC01551,RNFT2,ADAMTS6,GUCY1B1,MAP4K5,UBE2QL1,HPS5,C1orf94,ZHX1,NXPH2,ELOVL5,SYNPO,IGFBPL1,ZDHHC15,AGFG1,ZNF181,LRRCC1,TJAP1,USP54,ZNF678,NME9,SLC35G1,OLFM3,KCNJ3,STXBP5,LAMP2,HECTD2,ARHGAP12,NCOA7,PIK3AP1,MAOB,MAP4,MEIS1,MOBP,ERICH3,MRPL42,MSR1,MSRA,ZNF92,NEXMIF,ZNF862,NEK1,NEUROD1,NF1,CNOT4,GPR88,OXTR,KCNK10,PDE4D,BEST3,SNX10,XRN1,KCTD15,GPSM2,HMGCLL1,MTRF1L,LRP12,ING3,TMEM235,TATDN3,RANBP3L,RASGEF1B,CEP41,GRAMD1C,SYTL2,SNRK,MTMR10,PTHLH,TMEM260,STK32A,PID1,CEP97,TMEM255A,FAM66C,SH3TC2,FAM184A,KHDRBS2,RGS3,SEC61A2,PBRM1,SETD5,EXD2,CARF,CCDC25,RPL15,FBXW7,TCP11L1,LRRK2,LGR4,ABCA11P,RTKN,TRAPPC13,MIR124-2HG,SATB1,FAM19A1,LINC00461,ELMOD1,SH3GL2,NTNG1,MAGI3,FNDC3A,SEC31A,RAB3GAP1,CCDC88A,LIMCH1,UNC80,CLUAP1,ERC1,ZC3H13,CLASP2,TROVE2,ZNF302,SYNE2,NUDT10,ANKRD12,MTCL1,CAMTA1,ATMIN,ZEB1,TRIM2,RPGRIP1L,SYNE1,OBSL1,SIK3,AP4E1,GZF1,DDHD1,TMPO,R3HDM1,TPD52,TPM1,TRPC3,ANKRD20A2,SGK3,USP1,ZNF709,BCL2L13,MEAF6,TBC1D15,NSD2,ZNF711,MICU3,KCNT2,FSTL5,ZNF195,CA10,SLC30A4,PRDM10,MDH1B,SLC17A7,PARP11,PDSS2,MARCH8,PHTF2,FRMD6,GAN,SPATA13" MicroRNA hsa-miR-449c:mirSVR_highEffct hsa-miR-449c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.86E-107 2.73E-103 3.35E-106 3.09E-105 263 1049 "NDRG3,ADD2,ADORA2A,ZNF608,GPR158,KCTD16,KIAA1324,ZNF578,TAOK1,LRRC7,ALCAM,FAM135A,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,API5,TMEFF1,ASCL1,CAPRIN2,ZBTB10,ATM,ATP1B3,DOCK11,ADAM23,CFLAR,SYNJ1,JAZF1,WASF1,CACNA1A,CALB1,THSD7A,PTBP2,CBLN1,CD86,DGKI,LGI1,MAGI1,DLGAP1,CHN1,RAB3C,EPS15L1,SULT4A1,HECTD1,TMEM155,FHL5,SLC4A7,SEC31B,PREPL,ENTPD4,NCOR1,CS,SIPA1L1,SOCS5,APPL1,PNPLA8,CTNND2,PUM1,PPP6R2,ST18,RIPOR2,TOX,ZFYVE16,CENPL,TMEM170A,ELMSAN1,RHOBTB1,RABGAP1L,ARNT2,USP3,DPP6,DTNA,DNM1L,E2F5,EDIL3,SEMA3D,CELSR3,APH1A,MBNL2,TENM1,ELAVL2,PLEKHA1,CALCRL,VPS13B,GPHN,EFS,NRN1,FAM198B,ZIC4,FDFT1,FGF14,FHL1,RGPD5,C2orf88,WDR83,FAM49B,STAU2,MSANTD4,GABRA1,GABRA2,GABRA3,ZMYND11,ARPP21,IQGAP2,TUBGCP4,MSTN,MALT1,GLS,TOX3,MAP7D2,GNAS,GOLGB1,GPD2,GPM6B,FUT10,GPR22,STMN2,GRM1,GRM5,TMEM25,RNFT2,MAP4K5,FRMD3,ELOVL5,AGFG1,SHISA6,IGFBP1,INSM1,ITPKB,KCNA1,KCNMA1,KTN1,LAMP2,PAXBP1,NCOA7,LSS,C2orf80,MAN2A2,MAT2A,MBP,MDM4,MITF,SCG3,CTNNA3,MYCN,MYO9A,NEK1,NEUROD1,NF1,CNOT4,OPHN1,CNTN3,PDE3B,PDGFRA,CDK14,ABCB1,PIK3C2A,XRN1,JAKMIP1,PLIN1,EXOSC10,ING3,MAPK4,MASP1,VPS13C,SIDT1,ELOVL2,PTPRG,QDPR,USP47,RAP1GAP,RDX,TRIM68,ERI2,FIGN,RGS4,SLC25A36,RIC8B,TMLHE,SPIN3,ATP8B4,ATAT1,SCN3A,SCN7A,SCP2,ELMOD1,SLC30A10,HSPA4L,ITSN1,ST3GAL3,CTXN2,ANKRD6,PPP4R3A,SLC12A2,DMRTC1,CDK5RAP2,INTS9,RIMS1,PALLD,MYO16,FAM219A,SON,MYT1L,TNIK,HECW1,MYCBP2,SPP1,ZC3H13,KIF1B,CDK19,NPAS3,RAP1GAP2,ATP10B,CLASP2,ITPRID2,ZC4H2,NKAIN2,ERBIN,ADHFE1,SULF2,VPS13A,SYT1,MTCL1,FAM208A,ATMIN,ZEB1,TRIM2,SYNE1,GPRIN3,ITGB3BP,TLR4,RIMBP2,PRRT1,DCBLD1,KCNE5,TSN,HIRA,UBTF,WIPF1,NSD2,CLDND1,SF1,PCDH20,ZNF540,ZNF74,FSTL5,ZNF184,ANKS1B,CA10,EMSY,CADM2,DNALI1,SLC38A1,LMAN2L,ADAMTS9,NAV3,FAM47E,FBXO36,CASC15,JMJD1C,NHSL1,NETO2,NETO1,JPH3" MicroRNA hsa-miR-555:mirSVR_lowEffct hsa-miR-555:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.03E-107 2.83E-103 3.46E-106 3.19E-105 276 1154 "SDE2,ACADM,SYS1,GALNT13,SNX32,RTL9,OSBPL8,CC2D2A,ABCD2,AMT,OGT,CNIH2,API5,AQP6,MIER1,TMEFF1,ARRB1,CAPRIN2,NUMB,CCAR2,DDX3Y,CADM3,TTLL9,BBS2,CDK5R1,BSN,CDK5R2,CAMK2G,SYT6,CCNH,INA,CBFA2T2,ZBED1,LARGE1,MAGI1,CDO1,SOCS6,CNOT8,TAOK2,ARHGAP22,KMT2C,KIAA1549L,FBXO7,ABCG2,FHL5,RTTN,BAG4,CHD1L,CLOCK,CREM,CSF1R,OSBPL3,CTH,ST18,DOCK4,KATNAL2,KCTD8,MAML1,DAPK1,DAPK3,SPOCK2,AIF1L,DCC,SPATA2,DCTN1,MYEF2,SNAP91,RABGAP1L,ZNF582-AS1,DNM2,CASP8AP2,FAM57B,TSPAN5,HIPK3,CNNM1,HEYL,KLHL5,KMT5B,C8orf37,EPB41L2,DMTN,DENND4A,MRPL37,MRPL10,MRVI1,TUBB4A,FCGRT,FKTN,ZSCAN30,BAIAP2,SYNCRIP,IQCG,SEMA4D,EFCAB2,JKAMP,TVP23A,B4GALNT1,ZNF274,IP6K3,GATM,NEU3,ALDH1L1,LYVE1,ZNF276,RAB30,GPR75,ZNF638,MAP7D2,PCSK1N,GPT2,WDFY3-AS2,FUT10,PCLO,GRIA1,BVES,LRRC75A,CELF5,SMAP1,MYLK2,KNDC1,USP54,LRRTM3,SLC35G1,OLFM3,KCNA6,KCNC1,KCNJ10,KCNN2,KCNN3,TTYH2,MBNL1,MDM4,MEIS1,MN1,ZNF680,COL28A1,BLOC1S2,MTR,RSPO2,MXI1,ZNF862,NAP1L1,NASP,NCAM2,NF1,NINJ2,NOVA1,NUCB2,PBX1,PCDH9,PCSK1,PDE2A,PDGFRA,PENK,PFKFB2,PFKFB4,SSH1,PIK3C2A,ANLN,SNX10,FAM216A,FTO,PSAT1,SEPT4,POLR2F,PPARA,PPP2R2C,PTPA,DCHS2,MASP1,KLK6,QRICH1,PTPRD,FAM120C,PTPRZ1,ZSCAN2,ZNF615,NWD1,RASGRF1,ZDHHC14,SLC6A15,KIF7,MRPS18A,KLHL11,SLC25A36,ZFHX4,CCDC82,CARF,RORB,PCMTD2,NEK11,UEVLD,LRRK2,YJEFN3,KCNIP2,TRAPPC13,MIR124-2HG,ATXN2,HES6,TRIM46,ITSN1,SH3GL3,PPM1E,NTNG1,AMBRA1,ST6GAL1,ST3GAL3,CTXN2,NUBPL,PREX2,BTBD3,LIMS2,SLC6A8,CCDC88A,ATF7IP,SLCO1A2,USP33,WDTC1,TNIK,BDP1,SOX10,SPP1,SPART,C11orf87,CAMTA2,CEP68,MLC1,FGD4,ARC,SYP,KAZN,CAMTA1,DNMBP,KIAA1107,ANO4,TBX15,EHBP1,TCF7,ZEB1,RPGRIP1L,DOCK9,HIF3A,TEX15,C18orf54,AP4E1,HHIP,NACC2,TJP1,ZFP91,TPM4,PRMT8,ELP5,PPIL6,RUSC1,KCNE5,RFTN2,TMEFF2,GORASP1,FAM181B,ZNF709,CCDC136,VSNL1,CLDND1,AGMO,NDRG4,ZFAND5,CA10,PRDM2,ADAMTS9,TMEM178A,PCDH15,KCNAB1,SLC17A6,JMJD1C,TRAM2-AS1,ZDHHC20" MicroRNA hsa-miR-4266:mirSVR_lowEffct hsa-miR-4266:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.15E-107 2.89E-103 3.54E-106 3.26E-105 305 1400 "ACADM,ASIC1,C3orf14,GALNT16,ADCY6,SLC12A5,KIAA1211,AP2A1,MTUS1,GPR158,SPARCL1,CARNS1,PITPNM2,LRFN1,EP400,KCNAB2,PPFIA3,LGR5,PDXK,CASK,ASPH,PCDHGB4,SLC4A4,NOL4,CARMIL3,MPDZ,CFLAR,FUBP1,CACNA1I,VSTM2A,CAST,SHISA7,USP2,P2RX6,ARHGEF1,SYNGR3,CD38,LRBA,ARHGEF2,CDH8,LGI1,GPR37L1,CHM,CASC2,CPNE6,NRXN3,DGCR9,NIPBL,CNGA3,CNN3,PCYT1B,AKAP6,BTF3L4,LETMD1,CNRIP1,MFSD4A,SLC35F1,FAM171B,PNKD,AKAP12,ABCG1,CS,SEC24C,PDE4DIP,ERC2,GREB1,PUM1,KIAA0408,ARHGAP32,ZNF337,LONRF1,LIN54,GIT2,ARMCX4,YTHDC1,DCT,PLEKHM1,MAGI2,GSDME,POM121,SRGAP3,DMTF1,CASP8AP2,DPYSL2,ABI1,DNAJB6,ABCC5,TMTC1,YAF2,CELSR3,MBNL2,ABI2,RCAN2,KCNMB2,CLVS1,FABP7,TMEM132C,CHST15,FCGR3A,ZNF589,MED12L,CAP2,AGAP3,FLT1,NELFCD,JKAMP,HVCN1,STAMBP,KBTBD12,AP4B1,FYB1,DENND2A,FAM120B,RAPGEF6,ARPP21,GAP43,GATM,IGSF5,NEU3,GGT7,KIRREL3,LYVE1,TXNL4A,LNX1,PSRC1,GRIA1,RFFL,GRIK2,GRIN2D,NR3C1,GRM2,PRDM5,CIT,GSTM5,GSTT2,SOX21,CELF3,MAEL,TNFAIP8L3,LINC01102,HNF4G,HSF2,MSL1,KIAA1755,KCNQ3,IPO5,STMN1,SYTL4,NCOA7,ASPRV1,GPR155,MAPT,CHIC1,TM6SF1,MEIS1,MKLN1,MOBP,ZNF680,BLOC1S2,MYT1,P2RY13,NFE2L2,LRIT2,NTRK2,OCRL,GPR88,OGG1,PAK3,PCDHGC3,BEST3,PFKFB3,CAMKV,ANLN,CCSER2,PLCB2,PLXNB1,ING3,RETREG2,FA2H,POLR2F,PPM1B,LRRN3,PPP5C,VSTM2L,HYDIN,PROX1,WBP1L,LRRC49,SIDT1,QRICH1,PIGG,UHRF1BP1,BDNF-AS,TMEM260,PTPRB,EML5,PYGM,ZSCAN2,IQSEC3,RAP1GAP,DPF2,RET,GTDC1,PRIMA1,RPRD1A,ZFHX4,C12orf49,ALG9,RAVER2,CARF,SNX22,ARMH4,FBXW7,BAALC,MEG3,KCNIP2,NCBP3,SEMA6D,ATXN7,FNIP1,PEAR1,SEC14L1,SELL,ZFP30,FNDC3A,ST6GAL1,BCAN,CTXN2,ANKRD6,RPH3A,SIRT2,SLC15A2,COA1,SORCS3,CDK5RAP2,SNAP25,MBD5,ANKFN1,SNRPN,FAM219A,DOP1A,KIF21B,ERC1,UNC5B,IQSEC2,CDK19,CLASP2,ITPRID2,STOX1,NKAIN2,DIP2A,SULF2,FAM168A,MLC1,FGD4,SYN2,COBL,ADGRL3,TMEM136,NEU4,CUX2,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ARHGEF12,HIF3A,RNF216P1,SIRT1,AP4E1,HHIP,SLC44A1,THRA,HEY2,TMPO,TNR,PIK3R5,TPD52,NPL,SYNPO2,TRIO,TMPRSS5,TSC1,RFTN2,UBE3A,PITPNB,PLPP4,ZNF189,SYNC,SLC30A3,EMSY,LMAN2L,HPS4,UBE3B,NUP214" MicroRNA hsa-miR-618:mirSVR_highEffct hsa-miR-618:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.98E-107 4.48E-103 5.48E-106 5.05E-105 267 1083 "KDM5D,SLC25A25,CSMD3,NDRG3,AXIN2,CDC7,NLGN4X,SLC24A4,SLC44A5,INTS2,AK2,ADGRF5,LRRC7,FAM135A,DPP10,LCORL,PKP4,ALS2,LRRC4C,TNRC6C,USP37,MIER1,PPP4R4,ZBTB10,SLC4A4,MTMR9,NOL4,SEC11C,KSR1,DST,JAZF1,GPC2,ISPD,SPAG9,MAP7,ZNF501,METTL6,USP6,DGKI,MAGI1,NOG,SRSF11,CASC2,CLTA,CLTC,CNGA3,IGLON5,CNN3,ARMC8,SLC25A27,BTF3L4,LETMD1,TOGARAM2,ZFP28,ANKRD44,NCOR1,SIPA1L1,CNTNAP2,NRSN1,HDAC9,HDAC4,TMEM170A,SPOCK2,DCC,YTHDC1,DNAJC6,C8orf34,ZEB2,MYEF2,MAGI2,ALKBH8,PLPPR4,NTM,CHRDL1,DMD,NR1D2,PDCD6IP,ECM2,MAMLD1,ATL1,FRY,TENM1,EMX2,EPB41,EPHA5,SRRM1,TLR7,FAM198B,TMEM132C,DLC1,CEP78,GORAB,SEC24B,SLC9B2,FER,FGF13,FGFR3,BAIAP2,SEMA4D,ATP6V1H,ABLIM2,FYB1,PHYHIPL,GABRA1,ZNF44,GABRB1,GABRG2,GAD2,ARPP21,GALR1,DNER,HEPN1,BRD8,GLDC,GLS,GPM6A,LPAR4,CECR2,GRB10,GRIA4,FAM19A2,MAEL,HMGB1,HNF4G,NEGR1,SMAP1,EID2B,IRF8,ZNF181,C5orf24,KIT,INSYN2,HECTD2,LOC100128239,MAOB,MAP2,MAP4,MARK1,EFHB,MEIS1,SRSF12,AFDN,MTTP,LAYN,MYO6,NEXMIF,NAP1L1,FXYD6,NEK1,NF1,NOVA1,HCN1,NTRK2,NUCB2,IGSF11,CHAMP1,GPR137C,PAX6,PDYN,GPR85,GNG2,CYTL1,GDAP1L1,FAM218A,A2ML1,CCSER2,PLCL1,HMGCLL1,LRP12,ING3,EPB41L4B,MED1,PPP3CB,RAB39A,PRKCZ,HYDIN,DCHS2,PTHLH,PLEKHB2,NWD1,RAP1GDS1,OXR1,SLC6A15,FIGN,RGS4,KLHL11,RIC8B,NUDT11,RPRD1A,ZNF532,CARF,ROBO1,RORB,SPIN3,ZC3H14,MCMBP,ATP8B4,KCNIP1,CCDC112,SALL1,SCN2A,SCN8A,SH3GL3,CPEB3,FBXO11,FNDC3A,FHOD3,NUBPL,PPP4R3A,BTBD3,CCDC88A,SLC15A2,CPEB4,SMARCD3,MBD5,PDZRN3,USP33,SP4,KDM4C,ZNF423,ZNF302,NXT2,SYT1,AGTPBP1,DMXL2,SATB2,TRIM2,PCDHGB7,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,SIK3,HHIP,TMEM9,TJP1,TPM1,TRPC1,DCBLD1,UBE3A,TOM1L2,CCDC14,TBC1D15,WIPF1,ZFP37,ZNF711,ZNF45,LYPD6,CELF4,ZNF195,SLC30A4,PMEPA1,MDH1B,PCDH15,PLSCR4,RTN4,FBXO36,SNX14,KLHDC1,RNF146,SOCS4,GAN" MicroRNA hsa-miR-339-5p:mirSVR_lowEffct hsa-miR-339-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.65E-107 4.86E-103 5.93E-106 5.47E-105 319 1527 "CSMD2,PSMG3-AS1,SLITRK1,ADCY6,RNF157,GRAMD1B,ADORA2A,SLC24A4,SNX32,ZNF578,TAOK1,C1QTNF3,PDZD4,CDC42BPA,EP400,PPFIA4,APAF1,DGKD,CACHD1,AMER3,TNRC6C,IGDCC4,SPTBN4,ARRB1,MARK4,NUMB,ATM,RNF182,DPY19L3,RGS9,HCN2,NRP2,BMPR1B,SGCE,BTRC,SPAG9,USP2,MTMR7,TMEM257,ENTPD6,AP4M1,LOC730101,CCPG1,IGFN1,ADGRG1,ASIC3,CHRM1,NDST3,EPS15L1,COG1,TPP1,NMT2,STOML1,FBXO7,TJP2,TMEM155,COL11A2,ZNF521,IGDCC3,CHD1L,SLC32A1,ANKRD44,NCOR2,SNCAIP,CSF1R,RGS6,FEZ2,CSNK1G3,ATRNL1,PDE4DIP,UBXN2A,PPP6R2,EDRF1,GAPVD1,RIPOR2,TOX,RASSF2,TMEM170A,DAPK1,SCRN1,ZC3H11A,SNAP91,AK5,KBTBD11,ZNF582-AS1,EXOG,DNM1,USP3,GNE,HIPK3,GPR61,EGFR,ELAVL3,C3orf18,DCTN4,EN2,VPS13B,EPB41L2,COQ7,RABEPK,DENND4A,NCALD,VPS26C,F5,REEP2,FAM198B,TBC1D16,TESK2,ZNF589,FGF11,TMEM164,FHL1,AGAP3,FLT1,ANKFY1,EFCAB2,POMT1,PDLIM5,RASL10A,ERGIC3,NSG2,CGREF1,PNMA2,ABLIM2,TVP23A,ZNF512,GABRG1,AHCYL1,ARPP21,DISC1,GFAP,GFER,CRCP,LUZP2,KCNMB4,PRUNE2,PLCD4,GRM8,LINC01089,GSTM5,MAP4K5,C1orf94,ATXN2L,ARHGAP36,LINC01102,GABARAPL2,SYNPO,ZNF491,HNRNPK,TCEAL6,HSD17B1,FAM95B1,LIX1,ITGA7,GPR62,KCNMA1,KCNN2,A1BG-AS1,HECTD2,FGFBP3,ARHGAP12,ZFYVE27,MAP4,MOBP,SESN3,BLOC1S2,MSR1,MXI1,NCAM2,NME4,CNOT4,DNHD1,SLC11A2,HCN1,NTRK2,ZDHHC22,GLIPR1L2,PDE4D,PDGFRA,PFKFB3,PFKFB4,NLGN3,NLE1,PLCB2,MAGEL2,PPM1B,TATDN3,PPP2R2C,PRKACB,RAB39A,PRKCZ,GRAMD1C,CYBC1,DEF8,WDR25,BDNF-AS,PTH1R,SPDL1,PTPRB,PTPRO,USP47,SH3TC2,SLC6A15,GTDC1,RIC8B,RPL15,STK32B,HSD11B1L,ZNF331,FOXRED2,LRRTM4,ASAP3,HKDC1,AMBRA1,FHOD3,ANKRD6,WDR37,ZNF365,PEX26,EPN2,SLC6A7,SLC6A8,RADIL,SLC8A3,SIRT2,SLC9A5,SLC12A2,SLCO1A2,ARFGAP1,OGDHL,SORCS3,MYH15,PALLD,TMCC1,SON,FNBP1,ZSWIM8,SP4,LHFPL4,KDM4C,UNC5B,KIF1B,TSPYL2,NPAS3,ERBIN,NCDN,SEPT8,PHLDB1,PRRC2C,SYNE2,VAMP1,ARHGEF9,SYN2,SYP,TAC1,TACR1,EXOC7,FAM208A,ALG1,ADGRL3,ACSL6,DMXL2,SATB2,ZFP90,CLASP1,DOCK9,AKNA,AHCYL2,CYB561A3,DICER1-AS1,LEFTY2,TGFBR3,SLC44A1,GALNT17,THRA,ZFP91,KCTD2,SEZ6L,TPM2,TPM3,TPM4,DOK6,ZNF346,SMUG1,TRH,NEIL2,STXBP4,TRPC3,TSC1,TUB,ZNF709,VIPR2,GUSBP1,SLC13A3,CFAP298,ZNF711,SLC26A10,MKRN3,CELF4,ZNF154,TMEM237,EML6,SLC30A4,EMSY,PRDM2,NT5M,DNALI1,LINC02210,XKR7,TUBA1A,CIAPIN1,NAV3,FIP1L1,GOPC,UBE3B,FBXO36,CASC15,NUP214,MSRB3" MicroRNA hsa-miR-219-2-3p:mirSVR_highEffct hsa-miR-219-2-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-106 5.80E-103 7.06E-106 6.50E-105 275 1149 "ABAT,ADCY6,ERMN,INTS2,SNX32,HACE1,KIAA1324,C1QTNF3,LRRC7,AMPH,LRCH2,PPFIA2,PPFIA1,GPAM,APOC2,SHTN1,SPTBN4,CDK13,ASPH,NUMB,RNF182,B3GALT2,DST,SYNJ1,ST3GAL5,ARHGEF7,MTMR2,CA8,PTBP2,CAMK2G,CAST,ZNF501,CLDN10,LDB2,DGKI,LRBA,MAGI1,TIGD7,RCBTB2,CHN2,KMT2C,PPT2,COL4A5,ABI3BP,AHCTF1,MYRIP,ZFP28,MFSD4A,FAM171B,AKAP12,HAPLN1,GDA,SEC24C,FEZ2,ARHGEF10,APPL1,GREB1,RIMS2,DOCK4,KATNAL2,ZFYVE16,KIAA0586,ZEB2,SV2B,SPOCK3,G3BP2,DNAH9,PDCD6IP,DSCAM,RCAN1,EDN1,EDNRB,ANKRD46,RBM12,PHF20L1,ABI2,VPS13B,GPHN,RPS6KC1,ATP8A1,ST3GAL6,ZNF589,FER,KIAA1109,FGF1,SYNCRIP,ANKFY1,SLC37A3,SMC2,PDLIM5,TPK1,CAMKK2,ZNF605,CELF1,STAU2,MSANTD4,DOT1L,ABLIM2,GABRB1,BRPF3,GALC,MTHFD2,ZNF559,IGSF5,ALDH1L1,GGTA1P,GHR,BRD8,TXNL4A,GLYR1,GLRB,PCDH11X,GNAL,FERMT2,GPT2,PRUNE2,GPM6A,PCLO,DIDO1,GRIA4,GRIK3,GRM3,ZNF496,KIF3A,LINC00839,COQ10A,AP4S1,MAEL,HPS5,MAN1B1,LINC01102,HNRNPK,OPALIN,HSP90AA1,SMAP1,IFI16,RAB41,C5orf24,RBPJ,IL6ST,OLFM3,KCND1,IPO5,CYP27C1,ZFYVE27,MAP2,MARK1,LYPLAL1,MEIS2,AFDN,ZNF680,MSR1,CTNNA3,MXI1,MYCN,PABPC1L2A,P2RY13,NDP,NOS1,HCN1,OLR1,DPY19L2P2,SLC10A4,GPR173,A2ML1,PLCL1,PCDH18,TRHDE,MAPKAP1,SPATA6,PRKACB,PKIA,MAPK8,DCHS2,SYTL2,MDGA2,PLPPR1,BDNF-AS,MTMR10,TMEM260,PEX2,PEX5,USP47,RAD17,NWD1,RASGRF1,KHDRBS2,SLC6A15,RET,RFX4,RIT2,SEC61A2,SLC25A36,RNASEL,ROBO1,UEVLD,TRAPPC13,DGLUCY,ATXN2,SCN3A,SCN8A,GALNT10,CPEB3,FNDC3A,NLGN1,SLC1A3,FAM81A,BTBD3,EPN2,SEPHS1,SHANK2,SLC12A2,NAPB,ATF7IP,SLN,SNAP25,ZNF415,SNRPN,UNC80,IDI2-AS1,UNC5B,CLASP2,SSTR2,EPB41L3,TTBK2,SYT1,ANKRD12,MCF2L,CAMSAP2,TBX15,ATMIN,RPGRIP1L,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,TEX15,AP4E1,SLC44A1,TIAM1,BHLHB9,CSMD1,C5orf64,TPM4,RUNDC3B,NEIL2,RFTN2,CLHC1,UGT8,TBC1D15,ZNF781,ZBTB14,ZIC3,ZNF540,FMN2,TCEAL7,ZNF184,DHX33,PMEPA1,DNALI1,STOX2,PRDM10,PCDH15,PLSCR4,GOPC,DOCK8,HNRNPA3,PHTF2,ACTR3B,SLC4A10" MicroRNA hsa-miR-10a:mirSVR_lowEffct hsa-miR-10a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.03E-106 5.80E-103 7.06E-106 6.50E-105 321 1546 "NBAT1,CSMD2,FMNL2,TMEM132B,SLC12A5,SORCS1,GRAMD1B,NLGN4X,ZNF608,MTUS1,PCDH19,KCTD16,DISP3,TAOK1,SEMA6A,CEP126,AMPD2,ANK1,ANK3,FGD2,LCORL,CDK10,SFMBT2,SPTBN4,PLA2G4C,CDK13,BRINP2,DYNLL1,CHID1,SLC4A4,DPY19L3,ADAM23,BMPR1B,NAE1,LURAP1,CAMK2B,CAMK2G,SPAG9,ZNF501,METTL6,LRRFIP1,ZNF445,GPR37L1,NDST3,COG1,NMT2,FBXO7,TJP2,ABCG2,MAP4K4,NIPBL,CNGA3,ARMC8,SUMF2,LETMD1,TOGARAM2,HINFP,NCOR1,GDA,ABCG1,CS,LRIG1,FEZ1,CSNK1G3,SOCS5,VAC14-AS1,PDE4DIP,PPP1R16B,UBXN2A,NRSN1,EDRF1,HDAC4,DAPK1,ARMCX4,RUSC2,POM121,SRGAP3,WDR20,KBTBD11,GRIN3A,NYAP1,FAM57B,GNE,ECM2,TOM1,DNAJB6,E2F5,SNX29,FAM135B,RBM12,FAM13A,GPR61,MBNL2,IRAK4,COPS4,MRNIP,C3orf18,DCTN4,COQ7,LRRC17,RABEPK,DENND4A,ZNF549,VPS26C,DLC1,PPP1R1B,GORAB,POLR1B,TMEM164,PRKAG2,SEMA4D,FLT1,ANKFY1,JKAMP,ZNF605,ERGIC3,CELF1,CGREF1,STAU2,CHL1,GALNT15,GABRG1,RAPGEF6,ZNF559,ALDH1L1,WASHC2A,MMADHC,LYVE1,CRCP,MSL3,KCNMB4,GNAS,ATF7,TMEM121B,GRIK3,GRIK4,GRM3,GRM7,GRM8,LINC01089,BTN2A1,KLF12,BACH2,GABARAPL2,HNF4G,ZNF491,HNRNPK,NEGR1,OPALIN,HTR2A,ATCAY,FAM95B1,IDH3B,ITIH2,JAK1,GPR62,KCNN2,STXBP5,INSYN2,HECTD2,FGFBP3,NCOA7,LSS,CLEC18A,ZFYVE27,MAP2,MAP4,MBP,MGAT3,BLOC1S2,MSR1,MXI1,MYO6,MYO7A,NTRK2,NUCB2,CLDN11,ZDHHC22,PDE4A,PDGFRA,PIK3CD,A2ML1,ZFYVE21,NLE1,FTO,PLP1,SMIM7,PLXNB3,SEPT4,MED1,TATDN3,GRAMD1C,PSD,GON4L,BDNF-AS,PTH1R,TMEM260,PTPRO,ZSCAN2,TTC13,CCDC40,ZNF493,DPF2,GTDC1,UBR7,KCTD17,MRPS18A,ZNF532,RAVER2,CARF,KIRREL1,RPL15,ARMH4,UEVLD,MCMBP,ZNF568,ZNF331,FOXRED2,ATXN7,LRRTM4,TNFRSF19,IL17RB,SUPT20H,COPZ1,NLGN4Y,SGK1,ASAP3,FUZ,FBXO11,FNDC3A,URGCP,KANSL3,LRRC55,SEPHS1,RADIL,RAB3GAP1,SLC8A3,SLC11A1,BTBD7,CPEB4,MAPKBP1,MBD5,SNRPN,TMCC1,FAM126B,RBM34,MYT1L,SOX3,BDP1,LHFPL4,KDM4C,ERC1,UNC5B,KIF1B,TSPYL2,SPART,LHPP,LARP4,ERBIN,SEPT8,RGL1,KANK1,SEPT3,VPS13A,SYN2,ANKRD28,PJA1,DDHD2,FAM208A,UNC5D,TBCEL,IQCE,ACSL6,NEU4,DMXL2,SATB2,AZIN2,AKNA,ARHGEF12,TNS2,DICER1-AS1,AP4E1,TGFBR3,MTMR14,TLR4,TMOD1,TMPO,DAAM2,CSMD1,KAT6B,C9orf85,PRMT8,STXBP4,PPIL6,TSC1,OSBP2,FLRT2,ZNF709,VIPR2,WIPF1,CLDND1,LYPD6,CELF4,EML6,SPIRE1,ZFAND5,EMSY,CSDE1,LINC02210,TUBA1A,HPS4,PCDH15,FIP1L1,TRIM16L,PLSCR4,GOPC,UBE3B,ADAMTSL3,ZNF248,SSPN,SENP7" MicroRNA hsa-miR-874:mirSVR_lowEffct hsa-miR-874:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-106 6.93E-103 8.44E-106 7.77E-105 315 1493 "ABAT,EMILIN3,SYS1,XKR4,FMNL2,DSCAML1,ADCY6,GRAMD1B,PTCHD1,ADRA1D,SNX32,CEP126,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,APAF1,APBB1,DGKD,PHYHD1,SHTN1,CDC14B,SPTBN4,PLA2G4C,CDK13,ASTN1,SLC2A11,ADAM15,SNAI3-AS1,BCHE,RGS11,DST,MYRF,IL33,CACNA1B,CACNA1E,CAMK2G,TRIM41,ARHGEF25,CCKBR,USP2,P2RX6,CDC25B,LARGE1,CRLF1,CHN2,EPS15L1,NMT2,ABCG2,ARHGEF6,CABP1,ZFP28,MFSD4A,SEC31B,SH2B1,AATK,SNCAIP,SEC24C,NCAN,PLXNA4,SLITRK5,GREB1,CTNND2,PPP6R2,DCAF4,CYBB,HDAC9,FRMPD4,IST1,SPATA2,DGCR5,ZEB2,PLEKHM1,HP1BP3,FBXO25,GUCD1,SV2A,SGSM2,FAM107B,CCDC3,KIF19,DYNC1I1,DNM2,DOCK2,DPH1,DRD1,RCAN1,DYRK1A,SYT15,CNNM1,PHF20L1,SUGP2,EGFR,EGR3,TENM1,SRPK3,ELN,EML1,C8orf37,DMTN,EPS8,ZNF549,SPEG,CDHR1,SRARP,DUSP27,RASL12,F8,DLC1,ATP8A1,TOMM40L,ZNF589,FGF1,FGF11,FGF13,HPCAL4,IP6K2,COQ5,EFCAB2,WDR83,TMEM107,ZNF605,ERGIC3,DACH2,B3GAT1,AP4B1,ABLIM2,GABRA4,HBS1L,AHCYL1,GALC,ZNF274,ERAP1,MTHFD2,ATP8A2,GCK,GFAP,HEPN1,KIRREL3,RUNDC3A,CRCP,PSRC1,GPD2,CCDC184,MCHR1,DIDO1,GRM5,RNFT2,SLC2A6,PADI2,DDX19B,VSIG4,ELOVL5,CELF5,ATCAY,ICA1,KIAA1755,USP54,IL12A,INPP5B,ITPKB,CDH20,GPR62,KCNH2,KCNJ3,KCNJ9,KCNJ10,KCNK3,KIF5A,STXBP5,VWA5A,NCOA7,ZFYVE27,MBD1,LRP1B,AFDN,XRRA1,MOBP,CPNE9,SAMD5,PTOV1,MYO7A,SFR1,NNAT,NODAL,NOS1,CNOT4,HCN1,TBC1D25,ZDHHC22,PDE1B,PFKFB3,PFKFB4,SEMA5B,CCSER2,PKM,PLCB2,MTRF1L,PNMA3,SCHIP1,PRRX1,SEPT4,POU3F2,TMEM235,MED1,PTPA,PPP5C,PRKCG,PKN2,HYDIN,SLC22A23,SYTL2,SIDT1,ZSCAN32,PTPRD,PTPRN2,RAB3IL1,CCDC40,RASGRF1,ARID4A,BSDC1,RGS12,RNF220,PBRM1,LGI2,SNX22,EPHA10,BAALC,GLDN,SGSM1,MAP6D1,LRRK2,FAM161B,WLS,RTKN,PRCD,TNFRSF19,GALNT10,FOXRED1,ASAP3,MYO18A,NTNG1,SHC4,HKDC1,LIMS2,LRRC55,SLC6A7,ATF7IP,LGI3,NAXD,CXXC4,CDK5RAP2,PDZD2,SOX2,ZSWIM8,ENKUR,IZUMO4,KDM4C,NPAS3,DDN,C11orf87,CLSTN2,CAMTA2,ST5,SEPT8,ADHFE1,SULF2,AJAP1,ACSBG1,NUDT10,SYN2,KAZN,TAL1,UNC5D,ALG1,CNTN2,TBCEL,SMG6,TBX15,ATMIN,ZEB1,TMEM151B,ARHGAP9,TIAM1,CSMD1,LILRA4,ZNF346,SMUG1,TRIO,STXBP4,TRPS1,FAM155A,EIF4ENIF1,UBTF,FRRS1L,BCL2L13,LAT2,WRN,RICTOR,GUSBP1,FMN2,NDRG4,EML6,MEIS3,PRDM2,STOX2,XKR7,LMAN2L,ADAMTS9,CIAPIN1,PCDH15,NAV3,ZNF248,PIANP,SOCS4,LAS1L" MicroRNA hsa-miR-221:mirSVR_highEffct hsa-miR-221:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.52E-106 8.55E-103 1.04E-105 9.57E-105 260 1030 "RALGAPA1,ACADM,CLK4,ARID1A,CSMD3,AXIN2,ERMN,ESYT2,LRFN2,RTL9,WDR35,SPARCL1,PCDH10,PITPNM2,ANK3,CCDC146,PPFIA1,APAF1,MIER1,ASPA,CAPRIN2,ASPH,NUMB,DDX3Y,ATP1B3,ATP2B3,DPY19L3,LINC00847,BCHE,DST,CA8,CACNB2,CACNB4,CALB1,DIRAS1,PTBP2,LDB2,KRIT1,INA,DGKI,MAGI1,CLGN,SRSF11,NDST3,KMT2C,C4orf33,QKI,NIPBL,CNR1,ARMC8,AKAP5,SLC4A7,SLC4A8,CREM,RGS6,SEC24C,CST3,KIAA0040,USP6NL,KATNAL2,GAPVD1,TCAF1,TOX,ZFYVE16,KIAA0586,KCTD8,SPATA2,DNAJC6,ZEB2,MYEF2,SNAP91,SPOCK3,NR1D2,PDCD6IP,ARRDC4,DYRK1A,ABCC5,ABCC9,EBF1,ATL1,FCF1,EMX2,ABCA8,SEC24B,KIAA1109,OLFM1,POLK,NELFCD,SMC2,GAB1,GABRA1,GABRG2,GAD1,ZNF234,KIAA1841,MYOZ2,NEU3,SULT1C4,GDF9,GGTA1P,PPARGC1A,BRD8,GLI2,GLS,LUZP2,LOXL3,FERMT2,GPD2,GPM6A,GPR17,ATP2B1-AS1,GRIA4,NR3C1,ZBTB49,ADAMTS6,GUCY1B1,MAP4K5,TMEM179,MAEL,DDX19B,MIER3,AGBL5,HNMT,ZNF181,LRRCC1,PLD5,BRINP3,INSM1,CLVS2,KCNK2,KIF5C,KIT,KLC1,STMN1,HECTD2,NCOA7,MARK1,MAT2A,MEIS1,MEIS2,ADAM22,LYRM9,NAP1L2,NEFH,NEK1,NF1,NOVA1,OPHN1,CLDN11,GLIPR1L2,CDK18,PDE4B,PFKFB2,RETREG1,PDZRN4,RC3H2,MAGEL2,EPB41L4B,NXPH1,MED1,PPM1B,PPP2R5E,PPP3CB,PRKCZ,EPDR1,MAPK10,VPS13C,ANKHD1,PLPPR1,PTPN13,EML5,ZNF615,CEP97,ARID4A,KHDRBS2,RDX,ERI2,RFX3,RIT2,SEC61A2,SLC25A36,CARF,RORB,PCMTD2,MRAP2,BAALC,SPIN3,IL17RB,ZFP30,KIF16B,CPEB3,NTNG1,FBXO11,FNDC3A,SYBU,WDR37,PPP4R3A,WDR47,LRRC55,CCDC88A,SHANK2,TET1,CPEB4,SNCA,TMCC1,MYT1L,SOX10,HECW1,ZC3H13,SPART,C11orf87,POGZ,ZNF302,NXT2,ADHFE1,DDHD2,CAMTA1,EXOC7,FAM208A,AGTPBP1,TBCEL,TCEA1,TCF12,WASHC4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,ZFPM2,ITGB3BP,ERCC6L2,TMPO,RIMBP2,TP53BP2,TPM3,TRPC3,TRPS1,CADM1,SLAIN1,PLEKHH2,TRIM9,EML6,CADM2,PRDM2,RNF103,TUBA1A,SEMA3B,NAV3,SLC17A6,PLSCR4,GOPC,PAK5,MSRB3,NHSL1,AP3B2,SLC4A10" MicroRNA hsa-miR-4292:mirSVR_lowEffct hsa-miR-4292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-106 9.78E-103 1.19E-105 1.09E-104 330 1631 "ASIC1,XKR4,ADAR,PSMG3-AS1,SORCS1,ERMN,GRAMD1B,ADORA2A,UNC5A,KIAA1211,PTCHD1,BEND6,SNX32,HECW2,SORCS2,SMIM17,SEMA6A,PCDH10,MRTFA,AMPD3,OGT,PHF12,PPFIA1,APBB1,EPB41L5,DGKZ,GPAM,NT5C3B,PHYHD1,APOC1,TNRC6C,CPNE5,AQP6,PPP4R4,PDXK,MADD,ARHGDIA,DNAH17,MARK4,ZSCAN18,NUMB,ATP1A2,SLC4A4,ADGRB1,ADGRB2,SNAI3-AS1,RGS11,CFLAR,LDHD,ARHGEF7,CACNA1G,DDR1,CACNB2,BRSK2,CBR1,LDB2,DGKI,CDC25B,LRRFIP1,MAGI1,IGFN1,CASC2,SLC22A6,DLGAP3,EPS15L1,KIAA1549L,CLU,TJP2,NIPBL,IGLON5,ARHGEF6,PCYT1B,ARMC8,COL11A2,RCHY1,SMARCAL1,MYRIP,MFSD4A,SEC31B,RBM39,SH2B1,CRYBB1,ANKRD44,RGS6,OSBPL3,KIAA0040,ERC2,CFAP61,RUBCN,ECE2,NOS1AP,ARHGAP32,KATNAL2,PHF19,PHYHIP,DGCR5,KIAA0753,COPS7A,C2CD2L,MAGI2,FBXO25,SGSM2,DLG3,GRIN3A,NYAP1,DNAH9,SLC25A18,DNAJB6,RASA4,SORBS3,TNK2,C3orf18,SEZ6,ZNF549,SRARP,ETV1,RTN3,RASL12,F8,FAM198B,TBC1D16,SPSB4,FHL1,PCYOX1,AGAP3,FLNC,POMT1,TMEM151A,ARPP21,SEPT9,GCK,ALDH1L1,MMADHC,GGT7,HEPN1,RND1,STARD3,KCNMB4,GPT2,PSRC1,LILRB4,GPD1,GRIA4,GRIK5,SERP2,CIT,SOX21,FAM107A,PTGDR2,ATXN2L,BACH2,AGBL5,HNF4G,HNMT,HPCA,C9orf129,OPALIN,DHX35,HSD17B1,LRRC75A,SMAP1,MSL1,MYLK2,ZIC5,SCRT2,INSM1,C2CD4C,KCNJ11,KCNMA1,L1CAM,CAMK2N2,STMN1,SFXN5,PAXBP1,VWA5A,LOC100128239,MAN2A2,MAP6,MBD1,ADAM11,MITF,MOG,ADAM22,MTTP,C10orf105,SAMD14,FXYD6,NBL1,CCDC13,NFYA,NOS1,CNOT4,NOVA2,SETD4,PC,CDK18,PDE1B,PDGFRA,GNG2,BEST3,OLA1,GDAP1L1,PKD1,KCTD15,TNPO2,SH3KBP1,POLR2F,FSD1,TMEM235,PTPA,VSTM2L,RASGEF1B,PRKCG,MAPK9,GRAMD1C,HYDIN,CNNM2,GON4L,WDR25,ZSCAN32,CASTOR1,ZSCAN2,RALGDS,NWD1,ZNF493,BSDC1,RDX,CRTAC1,GTDC1,UBR7,RGS4,RNF220,PNMA8A,KIRREL1,CCDC25,RPE65,SNX22,EPHA10,GLDN,ADAL,ACER3,KCNIP3,CCDC112,S100B,HES6,PEAR1,TRIM46,SH3GL2,MYO18A,HKDC1,PAAF1,RPH3A,URGCP,DHX30,SLC6A1,KANSL3,SLC8A2,SEPHS1,SLC8A1,SLC8A3,SLC11A1,RCOR3,LIMCH1,PALLD,UNC80,SCN3B,TRERF1,NMNAT2,CAND2,CLSTN2,ZC4H2,SSPO,NCDN,MPRIP,ZSCAN29,DIP2A,KANK1,AJAP1,FNDC9,SYN1,TACC1,KAZN,SEMA4A,ALG1,ADGRL3,AGTPBP1,SMG6,NEU4,KIAA0930,TRIM2,TMEM151B,CYB561A3,ZMAT3,TGFBR3,HHIP,ARL10,KCTD2,PRRT1,CSMD1,KAT6B,RBFOX2,CDK20,NPL,TPM3,RGMB,ZNF346,METTL3,PRMT8,ZMYND8,FNDC5,AMOT,BEST1,CLIP2,CLDND1,ZNF70,ZNF74,LYPD6,MEIS3,INTS3,MAP3K12,PRDM2,NT5M,PRDM8,GAL3ST3,ITM2C,PCBP4,PAK5,VANGL2,AP3B2,ST8SIA2" MicroRNA hsa-miR-218:PITA hsa-miR-218:PITA_TOP PITA 1.99E-106 1.12E-102 1.36E-105 1.25E-104 185 506 "ASIC1,ACTN1,CSMD3,TMEM132B,GALNT13,USP31,SLC24A4,CASKIN1,LRRC7,SEMA6A,SYT13,TRMT9B,LCORL,PKP4,SHTN1,ARHGAP5,RGS20,NUMB,DPY19L3,ADGRB3,SYNJ1,CACNA1I,LDLRAD4,KALRN,DCLK1,FOXN3,SOCS6,CHM,NRXN3,NRXN1,NMT2,SLC35F1,HAPLN1,LRIG1,RIMS4,ERC2,CTNND2,PUM1,ST18,GAPVD1,FRMPD4,TOX,RIMS3,AIF1L,DBN1,ZEB2,ELMO1,MAGI2,RHOBTB1,SMG7,SPOCK3,SV2A,DLG2,HS3ST2,FAM13A,MBNL2,GOLGA7,PAN3,EPB41L1,ANKRD13B,EPS8,RTN3,MRVI1,NRN1,MED12L,STAU2,FUT9,B3GAT1,TMEM151A,GABRB3,BRPF3,PPARGC1A,GLS,TOX3,GNAO1,GNAS,GNG3,GPM6A,PCLO,GRIA2,GRIA4,GRIK2,GRIK3,GRM1,PTPRT,RNF165,TMEM25,GUCY1A2,KLF12,MIER3,HLF,ELOVL5,ZIC5,PLD5,SCRT2,KIF2A,INSYN2,LIFR,MBNL1,LRP1B,MITF,MDGA1,HS6ST3,NFIX,GPR137C,PCDH8,PDGFRA,ZDHHC8,SERPINI1,PIK3C2A,PIK3R1,TRHDE,FAT3,MINDY2,PPP2R2C,KANSL1,DIRAS2,RELN,RAP1GDS1,ZYG11B,RET,RNF220,ROBO1,ROBO2,LGR4,KCNIP3,ATXN1,ATXN2,SCN2A,SCN2B,SMPD3,SEC14L1,SHC4,FHOD3,ABLIM3,SLC1A2,WDR47,SLC6A1,CCDC88A,SLC12A2,RIMS1,MYO16,MYT1L,SOX5,KIF21B,SOX11,LMO3,ZC4H2,NKAIN2,MAPK8IP3,STXBP1,NUDT10,C3orf70,SYPL1,TAC1,TACC1,ANO4,TBX15,TCF4,SATB2,TCF12,SYNE1,DOCK9,PSD3,ARHGEF12,PUM2,CHST8,ZFP91,RIMBP2,TPD52,TUB,UBE2H,UGT8,TRIM9,CADM2,GDPD5,RNF103,NAV3,CAB39L,SLC17A6,PDSS2,RTN4,HNRNPA3,DPF3,GAN" MicroRNA hsa-miR-3119:mirSVR_highEffct hsa-miR-3119:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.26E-106 1.27E-102 1.54E-105 1.42E-104 303 1390 "ACHE,C3orf14,FAM43B,ADARB2,ADD1,AXIN2,BRAP,PWWP2A,BEND6,ADGRF5,CEP126,APAF1,APC,SHTN1,AQP4,MIER1,ARNTL,PDE8B,NUMB,RASL11B,ATM,N4BP2L1,NOL4,DPY19L3,ADGRB3,DCAF5,FUBP1,CACNA1I,SLC25A14,ZNF501,USP2,INA,ZMYM4,TIGD7,SRSF11,CASC2,CLCN3,NRXN1,SLC24A2,ABCG2,DNAJB5,QKI,CNGA3,IQCK,AKAP6,COL4A5,SMARCAL1,TOGARAM2,MYRIP,ENTPD4,CRHBP,AKAP12,GDA,LRRC3B,ARHGEF10,SUSD5,SLITRK5,PUM1,PPP6R2,ZFYVE16,EARS2,LONRF1,KIAA0586,KCTD8,PITPNC1,YTHDC1,JAKMIP2,ZEB2,MYEF2,HP1BP3,RHOBTB1,FAM107B,USP3,DNAH9,DMTF1,DRD1,WDPCP,EDN3,FCF1,PHF20L1,EGFR,EIF4G2,PLEKHA1,CERCAM,VPS13B,EPB41L2,ZNF549,TMEM74,DNAJC27,SIRPB1,F8,NSRP1,RACK1,GORAB,MED12L,POLK,SUCO,UBE2E3,CAP2,IQCG,ANKFY1,PSD2,NOP56,NELFCD,NBEA,AK8,ATP2C1,STAU2,ZMAT1,MEGF11,GABRA2,ZMYND11,ZNF274,ZNF559,DISC1,PCDH17,PPARGC1A,TTBK1,CRCP,ZNF638,GNAO1,GNAS,FERMT2,GPT2,LNX1,TDRKH,CECR2,RAPGEF4,RFFL,PRDM5,KIF3A,RNF165,AP4S1,GUCY1A2,SLC2A6,MAP4K5,ZHX1,ARHGAP19,HNRNPK,TLX1,ZDHHC15,OPALIN,HSP90AA1,HTR2A,MSL1,ZNF546,LRRCC1,SCIN,LIX1,IL6ST,ZNF385B,ITGAV,ITIH2,KCNJ3,KCNMA1,KHK,CYP27C1,KTN1,TTYH2,NCOA7,LYPLAL1,AQP11,MEIS1,POC1B,AFF1,AFDN,WDR49,SCG3,ZNF92,MTTP,MYO9A,NAP1L1,NPTX1,NTRK2,NUCB2,P2RY1,GPR137C,PCSK5,PCSK2,PDE1C,PIRT,PDYN,GDAP1L1,NOMO2,ANLN,PIK3CD,ZNF655,SNX10,HMGCLL1,PDZRN4,MED1,PPP3CA,PPP3CB,PRKAB2,PKIA,PRPSAP2,RELN,LRRC49,GDPD2,SNRK,CNTLN,UHRF1BP1,ZIK1,FAM120C,ZNF844,RAP1GDS1,VEPH1,DPF2,ERI2,RFX3,RFX4,RGS7,SEC61A2,PBRM1,RNASEL,RPRD1A,ZFHX4,ZNF568,MIR124-2HG,LRFN5,SCN7A,FNIP1,PPM1E,ARX,MAGI3,PPP4R3A,BTBD3,DHX30,SLC6A8,ZNF430,SEPHS1,RAB3GAP1,CCDC88A,SMARCC2,SMARCE1,RCOR3,MBD5,SNRPN,USP33,SOX1,BDP1,KIF1B,ATP10B,ITPRID2,ZNF302,SS18,ZSCAN29,SEPT8,RGL1,GSE1,NECAB1,ZFR2,MTCL1,DMXL2,TCF7,TCF7L2,SYNE1,NAT16,RALYL,PUM2,GPRIN3,SIRT1,C18orf54,ITGB3BP,TGFBR3,SLC44A1,ASXL3,ZFP91,C5orf64,TPD52,SYNPO2,TRIO,RUNDC3B,TRPC1,TRPC3,RFTN2,PRR18,CLHC1,CADM1,RPRM,WIPF1,NPDC1,XPO1,ZIC1,ZNF708,ZNF28,TRIM9,ZNF138,ZNF189,FTSJ1,ZFAND5,EMSY,LRP8,STOX2,FAM47E,MVB12B,DOCK8,RTN4,PAK5,SSPN,PIANP,FRMD6,SLC4A10" MicroRNA hsa-miR-670:mirSVR_lowEffct hsa-miR-670:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.62E-106 1.47E-102 1.78E-105 1.64E-104 342 1745 "SERPINA3,ABHD6,NCKAP5,SYS1,CSMD2,TMCC3,SORCS1,LRFN2,KIDINS220,DPY19L2P4,SNX32,PCDH19,TBC1D14,SORCS2,CC2D2A,C1QTNF3,ALCAM,ZNF687,TRMT9B,AMPD2,ANK3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBB2,GPAM,DGKD,SFMBT2,TMEM263,SPTBN4,LINC00173,MARK4,ZSCAN18,SLC4A4,ATP2A2,NOL4,ATP6V0A1,BACH1,ADGRB2,BCL2L2,DST,LINC00906,MYRF,MMD2,CACNA1D,CACNG1,CAST,BRSK2,SPAG9,NFS1,METTL6,USP6,USP2,P2RX6,AIFM1,ZMYM4,CDH18,LGI1,NUMBL,CFL2,FOXN3,B4GALT6,EPS15L1,RAB33A,PPT2,CLCN4,NRXN1,TPP1,SRP14-AS1,ANKRD35,SLC4A8,IGDCC3,ZNF385A,SEC31B,HINFP,ABCG1,ARHGEF10,MICAL2,CSNK1E,CSNK1G3,CNTNAP2,FAM169A,UBXN2A,GREB1,EDRF1,RIPOR2,RASSF2,TBC1D5,IST1,TMEM170A,DAPK1,AIF1L,ARMCX4,SPATA2,YTHDC1,ZNF804A,COPS7A,DDX46,DLG2,GRIN3A,EDNRA,ANKRD46,CNNM1,SH3GLB1,GPR61,KMT5B,ABI2,AASS,COPS4,ING4,ELAVL4,C3orf18,ANKRD13B,DENND4A,NCALD,SPEG,ANKMY1,EZH1,FAM198B,WAC,DLC1,ZNF589,SPSB4,PRKAG2,SEC23B,FOXM1,ANKFY1,NOP56,TMEM107,SMC2,RASL10A,ZNF605,NSG2,CGREF1,DOT1L,ZNF512,OGA,DKK3,AHCYL1,BRPF3,ZMYND11,IP6K3,GHDC,TMEM8B,DISC1,SEPT9,GFER,PPARGC1A,TNRC6A,STARD3,DCLK2,LILRA2,GRM7,GRM8,SOX21,GUCY1A1,FAM222A,RASSF8,BACH2,HPSE2,CPT1C,DHX35,HTR5A,ZNF546,LIX1,ITGA7,GPR62,CLVS2,KCNJ3,KCNJ10,KCNK3,KCNN1,KIF5A,KIFC3,KLRC2,STXBP5,SYTL4,HECTD2,MAP6,MAT2A,SYT9,LDLRAD3,KCTD6,PPM1L,MOBP,MSI1,JAKMIP3,CTNNA3,LYRM9,RTL5,ZNF862,BEX5,NAP1L1,CNOT4,NOVA1,NTRK3,NUCB2,PBX1,DPY19L2P2,PDCD2,PDE3B,PFKFB2,CDK14,ZDHHC8,DUSP26,PIK3CD,ZNF655,A2ML1,SCHIP1,ING3,MBOAT7,TNPO2,POLR2F,POU3F2,POU6F1,MED1,PPM1B,PTPA,RANBP3L,MASP1,RELN,SIDT1,PTCH1,PTH1R,PTK2,PTPRO,RAB5B,FAM66C,RAP1GAP,RASGRF2,ZDHHC14,BSDC1,SLC6A15,RET,RFX4,MRPS18A,RIC8B,RNASEL,LGI2,ROBO2,ELP2,RPE65,ACER3,ST6GALNAC6,ATAT1,KCNIP3,RTKN,ZNF568,MAPK12,SCN4B,TNFRSF19,ASIC4,IL17RB,SUPT20H,TRA2B,ITSN1,HKDC1,AMBRA1,CHD9,ST6GAL1,BCAN,WDR37,ABLIM3,RPH3A,PKNOX2,YPEL4,SLC14A1,ELMO2,SLC20A2,ATF7IP,ABTB1,SMARCA4,MAST1,SORCS3,CDK5RAP2,MBD5,TMCC1,PDZD2,WDTC1,KIF21B,SOX11,SOX15,GLT8D1,ERC1,ARHGAP26,SSTR2,RGL1,DIP2A,FGD4,JMJD6,SUPT5H,ADAMTS17,SYN2,ANKRD28,SLC37A2,ROBO3,MCF2L,UNC5D,ALG1,VWA3A,SATB2,TRIM2,DOCK9,OBSL1,TNS2,FRYL,FAM200B,PMS2CL,DICER1-AS1,TK2,LRRC8A,TNFRSF1B,TPD52,TPM3,C9orf85,TRIO,RUNDC3B,TRPS1,SLC35A4,GORASP1,NSD2,ZNF74,GPR158-AS1,SLC26A10,CRB2,LYPD6,CELF4,ZBTB38,ZBTB16,TMEM237,MEIS3,TUBA1A,SEMA3B,FIP1L1,PLSCR4,DOCK8,RTN4,CASC15,NUP214,FAM219B,SOCS4,SENP7" MicroRNA hsa-miR-648:mirSVR_lowEffct hsa-miR-648:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.86E-106 1.61E-102 1.94E-105 1.79E-104 290 1279 "DGCR6,CLK4,ACTN1,TMEM132B,SLC24A4,CASKIN1,KIAA1324,WDR35,OSBPL8,MRTFA,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APC,EPB41L5,GPAM,VAT1L,CDK10,CASK,SPTBN4,ARHGAP5,CADPS,STK33,CCDC74A,ASPH,ASTN1,INSYN2B,ZNF583,ATP6V0A1,ADAM15,ADGRB2,BARD1,BBS2,BCL7A,BCS1L,CFLAR,ST3GAL5,CA4,CACNB2,P2RX6,CD86,LRRFIP1,LGI1,CACNA2D2,JAM2,LSMEM2,CPNE6,NRXN3,ZFYVE9,ABCG2,SRP14-AS1,IGLON5,FHL5,FAM149A,AKAP6,ABI3BP,ACBD5,HS3ST5,CLOCK,CDC42BPB,CREM,GDA,CS,SEC24C,ARHGEF10,MICAL2,CTNND1,CTNND2,LIN54,RIMS3,DGKB,PABPC5,ARMCX4,YTHDC1,HEPH,TMEM130,SPOCK3,SV2A,SEC16A,USP3,CASP8AP2,PDCD6IP,DSCAM,EDN1,RBM12,MBNL2,PLEKHA1,TNK2,EML1,EXTL1,EYA1,F5,CLVS1,ZNF461,ZIC4,TAOK3,ATP8A1,RACK1,KAT8,FGF14,SYNCRIP,FLT1,JKAMP,TACC2,DACH2,TBR1,TVP23A,CAB39,ARPP21,NCKAP1,ATP8A2,ADAM28,RUNDC3A,RNPS1,TOX3,ATF7,GRIA4,PLPP7,GRIK2,GRM7,GSTM5,BVES,ARHGAP19,BACH2,ACOT7,HPSE2,NEGR1,EID2B,INPP5B,JAK1,KCNA4,KCNJ16,KIF5C,KIT,KLRC2,KTN1,PAXBP1,SYTL4,VWA5A,MAN2A2,MAP6,MBNL1,SYT9,ADAM11,LRP1B,MEIS2,POC1B,AFF1,MMP16,ERICH3,SAMD5,MSR1,CTNNA3,RSPO2,BEX5,NCAM1,ZC3H12B,CCDC13,NEUROD1,NINJ2,NME4,SLC11A2,NTRK2,OPCML,PBX1,PCSK2,PDCD2,PFKFB2,SERPINI1,SNX10,NLE1,HMGCLL1,FAT3,MED1,MAPK4,HYDIN,MASP1,SIDT1,SNRK,QRICH1,WDR25,BDNF-AS,PTHLH,PTK2,TMEM260,RAB5B,RAP1GAP,RASGRF2,SLC6A15,GTDC1,RFX4,SEC61A2,CARF,ROBO1,YY1AP1,RPL15,UEVLD,RPL38,ST6GALNAC6,WLS,ZNF331,ATXN7,PRCD,NLGN4Y,KIF21A,ARX,ST3GAL3,SLC4A3,RUFY2,RAB3GAP1,ARHGEF40,SLC11A1,CDK5RAP2,SNAP25,CMTR2,PALLD,TMCC1,MYO16,WDTC1,SOX5,ZSWIM8,MYCBP2,IDI2-AS1,RBM26,DDN,NFASC,TROVE2,LRRC4,DIP2A,KANK1,AJAP1,FGD4,SYPL1,SYT1,SYT5,SEMA4A,EXOC7,FBXW11,MGRN1,TBX15,VWC2,SIN3B,TRIM2,NAT16,ARHGEF12,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TGFBR3,HHIP,GZF1,TJP1,ZFP91,TMOD1,PRRT1,TPM1,TPM4,RGMB,SYNPO2,FNDC5,TSN,TUBB2A,FLRT2,LMF1,CLDND1,GUSBP1,ZNF540,FMN2,MKRN3,ZNF138,LAMP5,PRDM2,PRTFDC1,RGMA,CSDE1,MDH1B,LINC00632,FAM13C,PHTF2,CAMK1G,ADAMTSL3,TIGD6,RNF170,TTC7A,PIANP,SPATA13" MicroRNA hsa-miR-3158:mirSVR_lowEffct hsa-miR-3158:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.10E-106 1.74E-102 2.10E-105 1.94E-104 313 1480 "RALGAPA1,ADD3,GPR158,RTL9,ADGRF5,MRTFA,PKP4,APBA2,USP37,LGR5,SEMA4G,PRX,IGDCC4,MARK4,ASPH,NCOA1,NUMB,DDX3Y,ALDH7A1,ATP6V0A1,RIPK1,SNAI3-AS1,LINC00847,BCL2L2,BMPR1B,ARHGEF7,CACNA1B,CACNB2,CACNB4,PTBP2,TRIM41,PRC1,USP2,CBFA2T2,NEURL1,C1orf52,CDK11B,CDH18,FOXN3,CHM,CHN2,PLEKHB1,B4GALT6,EPS15L1,NRXN2,TPP1,NMT2,CLTA,FBXO7,CNGA3,IQCK,SUMF2,SMARCAL1,CREM,GDA,CS,SNCAIP,RGS6,SEC24C,FEZ1,CSNK1E,CHD5,NCAN,PDE4DIP,CNTNAP2,PPP1R16B,PLCXD3,GREB1,ARHGAP32,ZFYVE16,INTS1,SCRN1,SIRPA,RUSC2,C2CD2L,CEP170,BLOC1S6,SMG7,SRGAP3,TMCC2,DLG2,DLG4,HS3ST2,SLC25A18,PHC2,SYT15,HEYL,FAM13A,PHF20L1,MBNL2,ABI2,AASS,EIF4G2,EIF1,HSD17B14,SEZ6,KCNMB2,STX2,ERBB2,DENND4A,CEP85L,MRPL10,F5,CLVS1,FABP7,ZIC4,RACK1,CHST15,FECH,POLR1B,FGF13,SUCO,IP6K2,FLT1,PSD2,AKAP3,CGREF1,PNMA2,ABLIM2,ZMAT1,MEGF11,GABRG2,DENND2A,AHCYL1,B4GALNT1,JPH4,RAPGEF6,SALL3,ZNF559,ATP8A2,LRRC37A6P,GCNT2,CSDC2,TTBK1,COPS8,MSL3,GPT2,ADGRA3,BTN2A1,GSN,LINC01551,ATOH8,LINC01102,HMGCL,HP,NEGR1,SHISA6,SMAP1,IRF8,SHISAL1,ZNF546,NKD1,LIX1,IL6R,IL6ST,DIPK1A,ZNF385B,SLC35G1,KCNA6,KCNB1,KCNN2,GATD1,CREG2,INSYN2,MAP4,SYT9,MITF,CD200,MPP2,ERICH3,MTTP,ZNF862,P2RY13,NASP,NEFH,NF1,NFYA,NME4,LRIT2,NTRK2,IGSF11,OPHN1,PAK3,DPY19L2P2,PDE3B,GNG2,GDAP1L1,ZNF655,SNX10,TMEM38A,ST8SIA5,PLCL1,MTRF1L,SCHIP1,SDK2,FAT3,POLG,MED1,PPM1B,PPP3CB,CEP41,HYDIN,PRPH,MASP1,NDUFS7,BCAS3,WBP1L,GDPD2,BDNF-AS,PTK2,TMEM260,ZIK1,OCIAD1,ZSCAN2,NKAIN1,TUG1,MARCH1,SLC25A48,RALGDS,RBBP6,RFX2,RFX4,ZDHHC4,RPRD1A,ZNF532,CARF,ROBO1,KIRREL1,PCMTD2,SPIN3,STK32B,SYNDIG1,MEG3,RTKN,SEMA6D,FAM19A1,FERMT1,SEC31A,DZIP1,LRRC55,SLC12A2,SLC12A4,NAXD,SLN,SMARCC2,SORCS3,INAVA,MBD5,CABCOCO1,ZNF415,SNRPN,USP33,DOP1A,BDP1,ZC3H13,EPB41L3,ZC4H2,NKAIN2,KANK1,SULF2,SEPT3,ZC3H4,VAMP1,ARHGEF9,ADAMTS17,SYN2,ROBO3,TBCEL,VWA3A,EHBP1,SATB2,SZT2,SYNE1,OBSL1,AKNA,PMS2CL,AP4E1,SLC44A1,TMPO,C5orf64,NPL,RUNDC3B,TRPC3,RPL7L1,UGT8,FLRT1,ZNF709,VIPR2,MICAL1,ZNF24,TRIM9,ZFP41,FMN2,PLPP4,CELF4,ZNF177,ZNF189,FTSJ1,ZNF213,MAP3K12,PRDM2,SHD,RGMA,CIAPIN1,NAV3,NAV2,WIPF2,SLC17A6,ST7,CERS6,MSRB3,ADAMTS10,JPH3" MicroRNA hsa-miR-1914:mirSVR_lowEffct hsa-miR-1914:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.19E-106 1.79E-102 2.16E-105 1.99E-104 302 1383 "TTYH1,ABHD6,NDRG2,KLHL32,TMEM132B,ADD2,SORCS1,NLGN4X,AP2A2,SRPX,BCAR3,MRTFA,EP400,MAP4K3,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,DDO,AMER3,SHTN1,LGR5,CDK10,IGDCC4,ARHGAP5,ARNTL,STK33,DACT3,BRINP2,NCOA1,ASTN1,CCAR2,SLC2A11,ALDH7A1,NOL4,ADAM23,TTLL9,BCHE,RGS11,RGS9,BCL2L2,SYNJ2,ARHGEF7,JAZF1,SGCE,CABP7,VXN,TIGD7,NRXN3,CLCN4,CLTB,FAM189A2,HECTD1,COL4A5,COX4I1,CREM,AATK,SEC24C,VCAN,RASGEF1C,FAM169A,CFAP61,CTNND2,CCDC144A,PHF19,LONRF1,DGKG,ELMSAN1,C8orf34,DGCR5,PLEKHM1,KLHL3,ZC3H11A,GUCD1,SNAP91,SV2A,RABGAP1L,CCDC3,DLG2,DLG3,DMD,CD99L2,SLC12A6,DPH1,DPP6,PDCD6IP,DSCAM,ARRDC4,DTNA,ABCC5,EDIL3,SNX29,FAM135B,EGFR,PLXNC1,TMEM132E,GOLGA7,TMEM35A,EIF1,EPB41,EPB41L2,RCAN2,KCNMB2,SRRM1,NCALD,CEND1,ADGRV1,EZH1,FAM198B,TMEM132C,PTK2B,SCARA3,EFCAB2,WDR83,ZCCHC17,TMEM107,CAMKK2,ZNF605,ERGIC3,NSG2,DACH2,GPR153,DKK3,ZMYND11,GALR1,ZNF274,INPP5K,ACSS1,TUBGCP4,GPR162,CYP46A1,GFRA2,FREM1,SPIN1,RAB30,GLS,TOX3,LUZP2,GNAS,PRUNE2,DIPK1C,DIDO1,SERP2,AP4S1,RABL2A,SOX21,FAM107A,SLC2A6,RASSF8,GPR45,DDX19B,HMGB1,SYNPO,AGBL5,TLX1,CPT1C,AGFG1,GAREM2,KIAA1755,IBA57,INSM1,JAK2,KCNJ9,KCNJ10,KCNN3,KIF2A,KIF5A,INSYN2,ARHGAP12,LSS,ASPRV1,MAP6,SCAMP5,XRRA1,ERICH3,DBNL,CCDC80,MSR1,PTOV1,CTNNA3,LAYN,RTL5,FXYD6,NDP,NFIX,SETD4,PCSK2,CDK18,PDE2A,PDE4A,PDE4B,PDPK1,OLA1,PRRX1,PCDHB17P,PPP2R5E,RASGEF1B,MAPK4,PLPPR1,TMEM260,CASTOR1,RAB5B,RAD51D,OXR1,RASGRF2,RDX,CRTAC1,RGS7,KCTD17,RNASEL,RAVER2,CARF,MRAP2,EPHA10,GLDN,PAQR6,MEG3,ZNF331,ATXN2,SCN2A,ASIC4,SUPT20H,SH3GL2,AMBRA1,FHOD3,NLGN1,ST3GAL3,DZIP1,SLC4A3,FAM81A,EPN2,KANSL3,SLC12A2,SLC20A2,ATF7IP,SLC22A4,ABTB1,SMARCA4,SORCS3,CDK5RAP2,LIMCH1,SNRPN,PALLD,FAM126B,SOX2,NMNAT2,CLUAP1,ZC3H13,ARHGAP26,RBM26,TAB2,CLSTN2,POGZ,ERBIN,STAU1,KANK1,SULF2,GSE1,FAM168A,ARHGEF9,VPS13A,SYN2,SLC37A2,TAC1,ATP11A,TACC1,WSCD1,TCF7,TPCN2,SZT2,DOCK9,PUM2,TEX15,SIRT1,DICER1-AS1,ZFPM2,GALNT17,TJP1,ELP5,DCBLD1,RUSC1,SSBP2,HEPACAM,UBE2H,LINC00689,BCL2L13,MEAF6,CLIP2,XRCC4,ZIC1,ZNF711,CELF4,DPYSL5,ANKS1B,ZNF213,MEIS3,LRP8,RGS7BP,UBE3B,PHTF2,NUP214,ZNF248,TIGD6,SLC4A10" MicroRNA hsa-miR-4283:mirSVR_lowEffct hsa-miR-4283:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.96E-106 2.23E-102 2.68E-105 2.47E-104 296 1332 "ABR,ACADM,ASIC1,XKR4,GALNT16,SLITRK1,ADD3,ADORA1,ADORA2A,ADRA1D,LCNL1,SNX32,PCDH19,KCTD16,TBC1D14,PLA2G6,MRTFA,PDZD4,LRFN1,SUGT1P4-STRA6LP-CCDC180,APLP1,APP,CDK10,PDXK,ARSE,CDK13,MARCH3,STK33,DACT3,INSYN2B,RNF182,SNAI3-AS1,ADGRB3,LINC00906,C1QC,MYRF,DDR1,PTBP2,CAST,AIFM1,ARHGAP33,MAGI1,IGFN1,UBE2L6,SRSF11,TAOK2,NDST3,EPS15L1,KIAA1549L,TMEM59L,RAB26,MFSD4A,CHD1L,CPS1,CDC42BPB,AKAP12,GDA,OSBPL3,NCAN,RIMS4,RASGEF1C,NRSN1,PUM1,ECE2,KIF26A,SPOCK2,ARMCX4,ZEB2,PLEKHM1,KIAA0753,RUSC2,SMG7,SV2A,DMPK,TRAPPC9,DNM2,ACOT8,MAMLD1,EDN3,ANKRD46,TMTC1,PHF20L1,ABI2,AASS,EIF4G1,EIF5,TNK2,EIF1,EMX2,ENO2,SEZ6,KCNMB2,NCALD,SPEG,RASL12,REEP2,TMEM132C,TUBB4A,FCGRT,FGF13,AMOTL2,SGIP1,NOP56,AKAP3,DPYSL4,STAMBP,CAMKK2,NSG1,TVP23A,GCK,ALDH1L1,CYP46A1,ADAM28,GGT5,TTBK1,CRCP,GNAL,GNAS,GPT2,PRRC2B,STMN2,GRIA4,GRID1,ADAMTS13,GRIN1,GRM7,CLASRP,GSTM5,AP4S1,ATOH8,AGBL5,HSD17B1,HSF2,IRF8,IDH3A,FAM95B1,ZNF546,DOCK7,TJAP1,IGSF1,HES5,SCRT2,SLC6A17,KCNJ11,KCNN2,LINC00634,KLC1,TTYH2,STMN1,MAG,MAN2A2,ZFYVE27,MARK1,ADAM11,LDLRAD3,MPP2,GIT1,N6AMT1,HS6ST3,NDUFA5,NF1,NODAL,NPTX2,SLC11A2,NRGN,NUCB1,SETD4,PFKFB4,ZDHHC8,GDAP1L1,NOMO2,SNX10,PLCB2,ING3,RETREG2,POLG,PPP1R1A,PPP3CB,MAPK9,BCAS3,TMEM104,BDNF-AS,OCIAD1,PTPRE,CASTOR1,RAP1GAP,BSDC1,RGR,UBR7,LGI2,ARMC5,CYB561D1,ROBO1,BAALC,GLDN,STK32B,EMID1,SYNDIG1,KCNIP3,KCNIP2,RTN1,ZNF568,STX1B,HOGA1,SCN4B,ASIC4,FOXRED1,ITSN1,NTNG1,ST3GAL3,SEC31A,DZIP1,RPH3A,SLC1A7,DHX30,PKNOX2,SLC6A9,KDM4D,SLC8A3,SIRT2,CCDC88A,NAXD,ABTB1,SMARCA4,LIMCH1,CABCOCO1,TMCC1,SCN3B,BDP1,SP2,IZUMO4,ERC1,IDI2-AS1,LHPP,ZC4H2,FCHO1,NCDN,DIP2A,ADHFE1,ACSBG1,MLC1,ZFR2,ADAMTS17,ARC,SYP,TACR1,PDLIM2,WWC1,SMG6,VWA3A,TPCN2,SYNE1,TNS2,HIF3A,SPX,SLC44A1,THRA,TK2,ERCC6L2,KCTD2,TPM1,TPM2,TRH,ELP5,AMACR,UBE3A,VGF,VLDLR,RBFOX3,CLIP2,CLDND1,GUSBP1,XRCC4,LGI4,LYPD6,POLR3H,ZNF213,MEIS3,EMSY,PRDM2,DNALI1,STOX2,GAL3ST3,NAV3,CAB39L,WIPF2,PLD4,DOCK8,FBXO36,VANGL2,ADAMTS10,PIANP,CBLN2,AP3B2,ST8SIA2,SLC4A10" MicroRNA hsa-miR-876-5p:mirSVR_highEffct hsa-miR-876-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.44E-106 2.49E-102 3.00E-105 2.76E-104 277 1172 "ACADM,ARID1A,XKR4,TMEM132B,AXIN2,SORCS1,PWWP2A,NLGN4X,PCDH19,CC2D2A,TAOK1,SEMA6A,CARNS1,FAM135A,OGT,DPP10,ANK1,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,PARG,APBA2,PHYHD1,RGS20,ATP2B2,ATP2B3,RNF182,ALDH7A1,ATP6V1G2,RGS9,NRP2,CFLAR,CASTOR3,JAZF1,GYG2,CALB1,SLC25A14,SYT6,USP6,ZMYM4,TIGD7,SRSF11,CHM,MS4A7,KIAA1549L,QKI,NIPBL,AHCTF1,RTTN,AKAP12,SLC32A1,SNCAIP,CSF1,FEZ1,ARHGEF10,NRSN1,RIMS2,DCAF4,RUBCN,HDAC9,GAPVD1,PHF19,DAPK1,DBN1,DNAJC6,PLEKHM1,MAGI2,WDR20,DLG2,DYRK1A,DNM1L,GOLT1B,EDN1,PHF20L1,ELAVL2,TMEM35A,EPB41,EPHB1,ANKRD13B,SRRM1,CEP85L,ZNF549,NRN1,F5,F8,WAC,ZIC4,CEP78,TOMM40L,FKTN,TESK2,CAP2,FOXM1,ANKFY1,FOLH1,SMC2,USP16,TRIM16,NPTN,ST6GALNAC3,AP4B1,FYB1,GABRA2,GALNT15,GAD1,WASF3,TUBGCP4,TUBA8,SULT1C4,ARFIP1,SESN1,GK,GLYR1,GLRB,CBX1,GNAS,GPM6A,CCDC184,GPR34,PCLO,GRB10,GRIA4,GRM7,LINC01551,FICD,PSIP1,UBE2QL1,TNFAIP8L3,HMGB1,NEGR1,LIX1,OLFM3,KCNN3,KIFC3,KLC1,IPO5,NCOA7,SMAD1,MAP4,MAT2A,MBNL1,MEF2C,MITF,XRRA1,MSR1,MSRA,LAYN,NAP1L1,NAP1L3,NF1,DNHD1,LRIT2,NTRK2,NUCB2,OGDH,CLDN11,PAH,CNTN3,PAX6,PDYN,PLP1,PCDH18,PMP2,PMP22,ING3,MED1,PPP2R5E,PRKACB,HYDIN,SIDT1,SNRK,MDGA2,CNTLN,ANKHD1,PTPRE,PTPRG,ZNF615,CEP97,SLC25A48,RALGDS,NWD1,RAP1GDS1,ZNF493,RFX5,KCTD17,RIC8B,CARF,ROBO1,CCDC102B,UEVLD,RPL38,TCP11L1,ABCA11P,RTN1,ZNF568,SCN8A,GALNT10,NLGN4Y,ITSN1,PPM1E,SHC4,HKDC1,MAGI3,CHD9,ANKRD6,NUBPL,RUFY2,ZNF430,SEPHS1,ATF7IP,ZFP1,COA1,INTS9,SMARCE1,SNRPN,PALLD,KDM4B,SOX5,EMC1,SPP1,KDM4C,SPART,ZNF302,NKAIN2,SS18,NXT2,SULF2,GANAB,FGD4,PRRC2C,SYP,ANKRD28,SYT4,PJA1,DDHD2,EHBP1,ZFP90,CUX2,PCDHB4,NSD1,USP32P1,RNF175,SIK3,RNF216P1,ASXL3,TMOD1,RIMBP2,C9orf85,TPM4,RGMB,SYNPO2,TTC3,ZKSCAN5,CADM1,FAM155A,UBE2H,UBE3A,FRRS1L,DNAJC12,PLEKHH2,BCL2L13,ZNF781,ZNF708,MICU3,REEP1,EML6,SLC30A4,PRDM10,TMEM163,TRIM16L,EPM2A,AMN1,PHTF2,FBXO36,JMJD1C,KLHDC1,SOCS4" MicroRNA hsa-miR-876-3p:mirSVR_lowEffct hsa-miR-876-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.03E-106 3.39E-102 4.07E-105 3.75E-104 282 1215 "KLHL32,GALNT16,AP2A2,TBC1D14,SORCS2,SPOP,ARHGAP20,ALK,GPRASP2,AMPD2,OGT,DPP10,CCDC146,PHF12,SUGT1P4-STRA6LP-CCDC180,CDK10,ATP1A2,ATP2A2,ATP2B3,B3GALT2,ADGRB2,BCL7A,KSR1,WASF1,KALRN,CAMK2A,CANX,VXN,SYT6,VSTM2A,LDB2,C1orf52,SEPT7,REPS2,CDC42,CDH8,SRSF11,SOCS6,CHM,B4GALT6,LHX2,EPS15L1,KIAA1549L,NIPBL,IGLON5,CNTN1,PCYT1B,CREM,RBM39,TENM4,RGS6,CSNK1E,OSBPL3,ATRNL1,CST3,RASGEF1C,ERC2,ARHGEF4,NRSN1,ECE2,CCDC144A,TOX,KIAA0513,ZNF337,RASSF2,KIAA0586,DGKB,DGKG,ARMCX4,YTHDC1,DGCR5,ZEB2,ZBTB24,SRGAP3,AK5,USP3,CPEB2,ATN1,SGK2,CNNM1,SH3GLB1,ABI2,TENM1,ELAVL2,TNK2,EPB41L2,ZNF549,SPEG,RASL12,F3,F5,CACNG3,TAOK3,ZNF589,POLR1B,EVL,FLT1,COQ5,TMEM107,SMC2,PDLIM5,ATP2C1,CELF1,ST6GALNAC3,DOT1L,DKK3,HRASLS5,GABRB1,GAD1,RAPGEF6,NCKAP1,DISC1,IGSF5,GCNT2,PPARGC1A,TOX3,KDM2B,INSM2,POLL,LOXL3,GPD1,CECR2,ATP2B1-AS1,GRIA1,SPACA9,NR3C1,RNF165,GUCY1A1,GYG1,FAM222A,ELOVL5,DHX35,EID2B,IFI16,GAREM2,ZIC5,INPP5B,JAK1,KCNMA1,STXBP5,TTYH2,PAXBP1,LMO2,HECTD2,MAOB,MARK1,MBNL1,SYT9,CHST6,TM6SF1,BLOC1S2,ADAM22,MT3,LAYN,MYO9A,NCAM2,NELL1,NEUROD1,NEUROD2,NFE2L2,OCRL,PBX1,DPY19L2P2,GPR173,PRIMPOL,ANKRD16,SCHIP1,EPB41L4B,MED1,MINDY2,LRRN3,PPP3CA,SLC26A11,HYDIN,PROX1,PLPPR1,PTK2,TUG1,SLC25A48,FAT4,NWD1,RAP1GDS1,DBX2,FEZF2,KHDRBS2,ZYG11B,ERI2,GTDC1,MRPS18A,RIC8B,CCDC82,ZNF532,ALG9,ROM1,MRAP2,NEK11,UEVLD,PRR5L,ACER3,CNTNAP3,RTN1,SCNN1D,SH3BGR,PPP1R9A,KIF16B,AMBRA1,CCDC92,ANKRD6,WDR37,RPH3A,FAM214B,SLC8A1,SLCO1A2,NAXD,SMARCA4,SMARCE1,RCOR3,MBD5,DOP1A,SON,WDTC1,SOX1,ZSWIM8,SP4,MYCBP2,KIF1B,STOX1,NKAIN2,PHLDB1,SEPT3,VAMP1,FNDC9,TACC1,MTCL1,WWC1,CUX2,TPCN2,RALYL,FAM189A1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CRB1,TMEM9,HEY1,TK2,TMOD1,RIMBP2,KAT6B,RGMB,SYNPO2,TRPC3,FNDC5,SSBP2,LRTM2,SLAIN1,ZNF709,MEAF6,CLDND1,SLC47A2,ZBTB38,WNK1,EMSY,CADM2,SLC38A1,NAV2,SNX27,FIP1L1,WNK2,FZD3,ST7,HNRNPA3,CASC15,VANGL2,NETO1,CPNE4,FAM198A" MicroRNA hsa-miR-490-3p:mirSVR_lowEffct hsa-miR-490-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.59E-106 3.70E-102 4.44E-105 4.09E-104 305 1413 "RALGAPA1,ADCY6,PWWP2A,SLC24A4,MTUS1,CC2D2A,HFM1,SPARCL1,SEMA6A,ALCAM,CARNS1,LTBP4,BIN1,CCDC146,PPFIA1,SUGT1P4-STRA6LP-CCDC180,BCAS1,TNRC6C,API5,USP37,CPNE5,LGR5,ARNTL,ASGR1,ALDH7A1,ATP6V1G2,TTLL9,SNAI3-AS1,BBS2,BCL2L2,CACNA1E,SLC25A14,SYT6,BRSK2,RUNX1T1,PRC1,METTL6,USP6,TMEM257,CD38,C1orf52,CDH2,LRRFIP1,CCPG1,FBXO7,TJP2,MAP4K4,CNGA3,ARHGEF6,ABI3BP,CLOCK,FEZ1,SUSD5,IPCEF1,VCAN,ERC2,ST18,RUBCN,CYBB,KIAA0408,HDAC9,GAPVD1,IST1,DAPK1,ZEB2,MFAP3L,ALKBH8,SV2B,SEC16A,CHRDL1,DLG3,DMD,USP3,DNAH9,CD99L2,DPP6,ABCC5,DNM1L,ABCC9,EDNRA,SGK2,CNNM1,TMTC1,EFNB3,PHF20L1,SUGP2,EGR3,EIF1,EPB41L1,NCALD,CDKL3,RCSD1,RASL12,ADGRV1,ZNF461,TAOK3,SLC9B2,FGF1,FOXG1,EVL,SGIP1,NOP56,EFCAB2,JKAMP,NBEA,ERGIC3,OGA,STAG2,MEGF11,GABRA3,CAB39,RAPGEF6,ZNF274,ERAP1,SIGLEC8,INPP5K,KIAA1841,GATM,TUBGCP4,GFRA2,GGT7,CRCP,TCERG1,SPIN1,GLI2,OS9,GNAO1,GNG3,PRUNE2,STON1,GRIK2,SPACA9,NR3C1,PRDM5,GRM5,GSTM5,RNFT2,GUCY1B1,WIF1,FRMD3,HMGB1,SYNPO,ZNF491,OPALIN,ZIC5,LRRTM3,JAK1,JAK2,KCNC2,KCND2,KCNK1,KIF5C,STXBP5,VWA5A,ZFYVE27,MARK3,MAT2A,MATN2,MBD1,MBNL1,SYT9,MDFI,MDM4,LRP1B,MID1,MOV10,SAMD5,MTR,MYO6,HNRNPM,FXYD6,NCAM1,NEUROD1,NEUROD2,VWA2,ODF2,OPHN1,P2RX7,ZDHHC22,DPY19L2P2,PDE4B,PIRT,BEST3,CCSER2,SNX10,NLE1,ST8SIA5,SLC25A23,EPB41L4B,TNPO2,PPARA,MED1,PPP1R1A,PPP2R5C,PRKCZ,MAPK9,LRRC49,SIDT1,TMEM104,UHRF1BP1,MTMR10,ELOVL2,PTPRB,PTPRG,NKAIN1,RAB5B,SLC25A48,CCDC40,RAP1GDS1,RASGRF1,DBX2,GAL3ST4,RGS12,MRPS18A,RNASEL,ARMC5,FBXW7,SPIN3,ZC3H14,GLDN,LGR4,RPS20,ATAT1,TRAPPC13,FOXRED2,SCN2A,SCN4B,HES6,TNFRSF19,ELMOD1,SH3BGR,ZFP30,MYO18A,HKDC1,CHD9,ANKRD6,SLC1A3,LRRC55,SLC8A1,RAB3GAP1,ARFGAP1,SORCS3,SMARCD3,RCOR3,RIMS1,SON,MYCBP2,KDM4C,TEX2,SPTAN1,RBM26,NFASC,SRPK2,CLSTN2,COLGALT2,ZC4H2,MAPK8IP3,NEK4,RGL1,CAMTA1,TBCEL,KLHL4,ANO4,ATMIN,SYNE1,DOCK9,RALYL,NSD1,GALNT17,GZF1,ENHO,TMEM9,HEY1,ASXL3,ERCC6L2,R3HDM1,TNR,RASD2,NPL,RGMB,LRTM2,UBE2H,SLC35A4,AMOT,BCL2L13,MEAF6,NSD2,SF1,PCDH20,ZNF19,AGMO,LYPD6,PCBP1-AS1,ZFAND5,PMEPA1,EMSY,SLC38A1,LMAN2L,ADAMTS9,CIAPIN1,GAL3ST3,SLC17A7,WIPF2,SLC4A10,CPNE4" MicroRNA hsa-miR-1227:mirSVR_lowEffct hsa-miR-1227:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.76E-106 4.36E-102 5.22E-105 4.81E-104 311 1467 "RALGAPA1,ACTN2,KDM5D,FMNL2,ADD1,ADD3,ERMN,AP2A2,OSBPL1A,TAOK1,BCAR3,BBOX1,AMPD3,KIF6,LRCH2,USP28,PHF12,APBB2,APLP1,BCAS1,USP37,APP,MIER1,SFMBT2,ARHGAP5,MARCH3,MARK4,CAPRIN2,ATM,ATP1A2,ATP2A2,B3GALT2,SYNJ1,SYNJ2,GYG2,SGCE,CA8,CACNB4,CANX,ISPD,MTMR7,NEURL1,SEPT7,CDH2,CFL2,SRSF11,CASC2,MS4A7,RAB3C,CPNE6,NRXN3,MYL6B,NMT2,C4orf33,SRP14-AS1,TMEM155,AKAP6,SUMF2,MAGED1,MYRIP,CPS1,CRHBP,CREB5,CRMP1,TRIM69,ABCG1,CSF2RA,CSNK1E,OSBPL3,PDE4DIP,CNTNAP2,CFAP61,NRSN1,RIMS2,PPP6R2,RUBCN,CCDC144A,BOC,CENPL,TBC1D5,ARMCX4,SPATA2,ZNF804A,ZEB2,ZBTB24,B3GAT3,CEP170,SPOCK3,KBTBD11,ZNF582-AS1,EXOG,SLC29A4,NR1D2,DPH1,DTNA,DTNB,ECM2,DNAJB6,ABCC5,EDNRA,HIPK3,TMTC1,EFNB3,FAM13A,AASS,KCNMB2,ENPP6,ANKRD13B,EFS,ADGRV1,HSPA12B,F3,WAC,FKTN,ZNF589,FGF13,BAIAP2,PRKAG2,POLK,CAP2,SGIP1,EFCAB2,NBEA,HVCN1,APOPT1,DACH2,CGREF1,PNMA2,GAD2,IP6K3,GAP43,SRRM4,GFER,GGT7,GLYR1,TNRC6A,CBX1,PRUNE2,DIPK1C,MCHR1,NUDT21,TMEM121B,GRIA4,ATE1,GRM1,GRM3,GRM7,KAT7,ADAMTS6,SLC2A6,GYG1,WIF1,UBE2QL1,HPS5,GPR45,FRMD3,VSIG4,CPT1C,HSD17B1,SHISA6,HSP90AA1,C2orf72,RBPJ,DOCK7,USP54,INPP5B,KCNC2,KCNJ10,KLHL23,KCNK2,GATD1,ARHGAP12,MAT2A,MDM4,MEIS1,MID1,POC1B,XRRA1,MOBP,PTOV1,LYRM9,HNRNPM,NASP,NUCB1,OPA1,KCNK10,SNTG1,CDK18,GPR85,GDAP1L1,SSH1,XRN1,PKM,NLE1,SLC25A23,PRIMPOL,SCHIP1,PCDHB17P,PRKAB2,CEP41,GRAMD1C,MASP1,RELN,VPS13C,LRRC49,DEF8,GON4L,PTAFR,CCDC40,ATG16L1,FAT4,SUSD4,OXR1,RASGRF2,SEC61A2,DCUN1D2,SETD5,RAVER2,ROBO1,MRAP2,ATP8B4,GLDN,ACER3,RPS6KA2,PTGR2,HSD11B1L,WLS,ATXN7,PEAR1,SELL,FOXRED1,FBXO11,FNDC3A,FHOD3,SEC31A,PAAF1,LIMS2,SLC6A1,LRRC55,ZNF430,KBTBD4,CDK5RAP2,SNRPN,UNC80,PDZD2,TNIK,KIF21B,UHRF1BP1L,SPTAN1,KIF1B,SRPK2,ZNF621,ATP10B,TROVE2,POGZ,NKAIN2,INKA2,STAU1,NECAB1,VAMP1,PLCB1,UNC5D,ALG1,ATMIN,DMXL2,SYNE1,PCDHB9,ARHGAP9,FAM200B,ITGB3BP,THBS4,MTMR14,TJP1,ACTR6,TLL2,TLR4,TMOD1,KAT6B,TNNT1,TPM3,WBP2,ZNF346,TRO,STXBP4,PPIL6,TSC1,SSBP2,SGK3,ZNF610,RPL7L1,EIF4ENIF1,UGT8,WIPF1,NSD2,RICTOR,XRCC4,ZIC3,ZNF711,ZNF708,ZNF24,GPR158-AS1,MKRN3,TMEM237,PRDM2,HPS4,SEMA3B,PPP1R3F,EPM2A,RNF146,PRRT4,SENP7" MicroRNA hsa-miR-3149:mirSVR_highEffct hsa-miR-3149:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.52E-106 4.79E-102 5.73E-105 5.27E-104 273 1142 "CSMD3,ADORA3,DPY19L2P4,MTUS1,OSBPL8,TAOK1,C1QTNF3,LRRC7,ALCAM,PCDH10,FAM135A,MAP4K3,ANXA7,ALS2,AQP4,CDK13,ASPH,B3GALT2,N4BP2L1,SEC11C,SYNJ1,ARHGEF7,IL33,CACNB4,KALRN,PTBP2,USP6,CD86,DGKI,KCNAB3,MAGI1,CHM,CHN2,CASC2,RAB33A,NRXN1,AKAP6,LETMD1,SLC4A7,ZFP28,CNRIP1,MFSD4A,CP,ANKRD44,CSF1R,CSF2RA,ATRNL1,NCAN,SLITRK5,UBXN2A,CFAP61,ST18,ZSCAN23,ARHGAP24,FRMPD4,TOMM20,DBI,DCC,DNAJC6,ZEB2,ZBTB24,HP1BP3,DMD,PDCD6IP,ABCC9,AASDH,HIPK3,PHF20L1,EGFR,GOLGA7,ELAVL2,PLEKHA1,C8orf37,CALCRL,RABEPK,SRRM1,FAM198B,CEP78,FCGR3A,SLC9B2,KIAA1109,FGFR3,CAP2,IP6K2,RGPD5,PSD2,SLC37A3,AFF2,TPK1,ATP6V1H,ATP2C1,ZNF605,NRG3,GABRA2,GABRA5,ZMYND11,ARPP21,GALR1,DISC1,MSTN,GLRB,TOX3,PCDH11X,STARD3,KIAA1958,LUZP2,ATF7,GPR12,GRIA4,GRIK1,GRM7,GRM8,GUCY1A2,GYG1,MAEL,RASSF8,HAS2,HNF4G,ZDHHC15,IRF8,ZNF546,PLD5,OLFM3,KCNA4,KCND2,KCNJ5,KIF2A,PAXBP1,VWA5A,HECTD2,NCOA7,MAOB,MARK1,LYPLAL1,AQP11,MATN2,LRP1B,MEIS1,CD200,ZNF680,ADAM22,MSR1,P2RY13,NELL1,NEK1,NEUROD1,NEUROD2,NHLH1,HCN1,NTRK3,OLR1,OPA1,OPCML,OXTR,ZNF827,GLIPR1L2,PAK3,PAX6,DPY19L2P2,ETFRF1,PDE3B,PDE4B,GPR85,OLA1,NALCN,ANLN,PIK3R1,XRN1,PLIN1,MTRF1L,LRP12,PSAT1,EPB41L4B,POU3F2,PPM1B,TATDN3,NKAIN4,PRKCZ,HYDIN,PTAFR,PTHLH,PTPN13,PTPRE,ENOX1,VEPH1,RFX4,RGS4,CCDC82,DCUN1D2,ROBO2,GLDN,MEG3,RYR3,CCDC112,SEMA6D,SCN2A,LRRTM4,LINC00461,SCP2,FNIP1,ZFP2,MRAS,SH3BGR,ZFP30,ITSN1,FNDC3A,FHOD3,NLGN1,PAAF1,ZNF365,SLC1A3,PPP4R3A,RAB3GAP1,CCDC88A,BTBD7,SPHKAP,SLC22A4,ZNF667,SMARCE1,RCOR3,ANKRD36,MBD5,ZNF415,MYT1L,BDP1,SOX15,MYCBP2,KIF1B,RBM26,NPAS3,C11orf87,SST,SSTR2,TTBK2,VAMP1,FNDC9,SYPL1,CAMTA1,ANO4,TCF4,CUX2,TCF7L2,ZEB1,CLASP1,SYNE1,RALYL,SLC35G2,SLC44A1,TJP1,NR2E1,CSMD1,TPM1,RUNDC3B,TSN,ANKRD20A2,CADM1,USP1,NSD2,ZNF711,ZNF28,TRIM9,MKRN3,ZNF138,CELF4,FSTL5,ANKS1B,CA10,PRDM2,C12orf4,EPM2A,DNAH10,FZD3,PHTF2" MicroRNA hsa-miR-767-5p:mirSVR_lowEffct hsa-miR-767-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.47E-106 5.32E-102 6.36E-105 5.86E-104 320 1549 "VWA5B2,ABAT,ASPHD1,ACHE,KDM5D,XKR4,ADCY2,ADCY5,ADCY6,RNF157,ADD1,AXIN2,CDC7,SORCS1,GRAMD1B,RNF150,ADRA1B,KIDINS220,ZNF608,OSBPL6,ARHGAP20,PCDH10,KCNT1,ZFAT,OGT,ANK3,APP,LGR5,AQP4,TMEFF1,ARNTL,RGS20,BRINP2,ATP2B1,DOCK11,ADAM15,MPDZ,BCL2L2,MIR9-3HG,DST,WASF1,CACNA1D,KALRN,RUNX1T1,CCKBR,CERS5,INA,SCARB1,CD38,CD81,CDH8,DCLK1,ZMYM4,TIGD7,SOCS6,B4GALT6,CLTC,TJP2,QKI,MAP4K4,IQCK,ARMC8,AKAP6,WHRN,BTF3L4,MYRIP,MFSD4A,SH2B1,ARHGEF10,VCAN,SOCS5,ERC2,UBXN2A,GREB1,RIMS2,SEC14L5,NOS1AP,DOCK4,KATNAL2,RIPOR2,MATR3,KCTD8,GIT2,SIRPA,SPATA2,ELMSAN1,JAKMIP2,ELMO1,COPS7A,MED24,ALKBH8,SRGAP3,RABGAP1L,DMTF1,SLC12A6,ARRDC4,DTNA,ABCC5,ABCC9,FAM135B,EDNRB,SH3GLB1,PHF20L1,EGFR,KMT5B,EGR3,LPAR6,KCTD3,EIF4G2,IRAK4,ELAVL2,ELN,C8orf37,PAN3,SEZ6,EPHB1,ENPP6,CDHR1,MRPL37,TOMM40L,MED12L,POLR1B,SYNCRIP,AGAP3,FOXO3,NBEA,SMC2,TRIM16,MSANTD4,MPP6,PHYHIPL,STAG2,GALNT15,BRPF3,NCKAP1,ERAP1,ZNF559,DISC1,TXNL4A,PCDH11X,ADGRA3,GPD2,NUDT21,GRIA2,DIDO1,GRIA4,GRM5,GRM7,TMEM25,LINC01551,AP4S1,SOX21,PSIP1,ADAMTS6,HRH3,HNMT,LRRC75A,ICA1,C2orf72,IGF1,ZIC5,IBA57,LRRTM3,METTL21A,KCNJ10,KCNMA1,KIF5A,LINC00634,STMN1,LIFR,HECTD2,ZFYVE27,MARK1,MBD1,ADAM11,KCTD6,MITF,COL28A1,N6AMT1,NEXMIF,NCAM1,NCAM2,SFR1,NEFM,NELL2,NEUROD1,NFIA,OPCML,OPHN1,OPRL1,KCNK10,PCSK2,NLGN3,PIK3CD,ZNF655,PKD1,PKM,GPSM2,PLCL1,FTO,MTRF1L,STRN3,RETREG2,PPP3CA,PRKCZ,UHRF1BP1,PTHLH,TMEM260,ZIK1,PTPRB,NKAIN1,SLC25A48,RAD51D,OXR1,SLC6A15,RFX4,RGS12,RNF220,ZFHX4,ROBO1,KIRREL1,ROBO2,YY1AP1,ADAL,STK32B,KCNIP2,ATXN2,HES6,ASIC4,GALNT10,NLGN4Y,PPM1E,DOCK10,AMBRA1,DZIP1,WDR37,RUFY2,SLC6A1,SLC6A8,ELMO2,SLC20A2,IFT122,MBD5,WDTC1,ZSWIM8,HECW1,KIF1B,ZBTB43,RBM26,SPART,CLASP2,ZNF302,ZSCAN29,ELOVL4,CEP68,ADHFE1,KANK1,GANAB,FGD4,ZC3H4,ADAMTS17,SYN2,COBL,TAC1,UNC5D,TBCEL,TBX15,SATB2,ZFP90,SZT2,AZIN2,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1-AS1,ZFPM2,SLC44A1,TIAM1,TLR4,ZFP91,C5orf64,ZNF346,SYNPO2,ELP5,RUSC1,ANO5,TUBB1,SLC35A4,UBTF,ZNF709,LAT2,NPDC1,PCDH20,TRIM9,FMN2,SLC26A10,DPYSL5,ZFAND5,LRP8,LMAN2L,CIAPIN1,PCDH15,NAV3,URM1,TRIM16L,PCBP4,MPPE1,PDSS2,DOCK8,UBE3B,FBXO36,ADAMTS10,SLC39A12,IFT88" MicroRNA hsa-miR-500*:mirSVR_lowEffct hsa-miR-500*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-105 8.55E-102 1.02E-104 9.40E-104 288 1270 "SERPINA3,NCKAP5,CSMD2,FMNL2,ADCY6,RNF157,ADD2,SORCS1,ADORA3,RNF150,BEND6,SLC24A4,MTUS1,GPR158,OSBPL1A,TBC1D14,KIAA1324,OSBPL8,C1QTNF3,LRRC7,PCDH10,ANK1,CCDC146,USP28,GPAM,PHYHD1,BCAS1,TMEFF1,CDK13,STK33,NCOA1,SLC4A4,ATP2A2,B3GALT2,DST,LINC00906,JAZF1,CACNB2,PTBP2,SYT6,BRSK2,CBR1,INA,ENTPD6,ZNF445,MAGI1,CRLF1,UBE2L6,NUMBL,RAB33A,TPP1,TMEM184B,MFSD4A,SLC35F1,C2CD2,CRMP1,HINFP,ANKRD44,ABCG1,ARHGEF10,VCAN,VAC14-AS1,KIAA0040,ERC2,CTNND2,ST18,USP6NL,KIAA0408,GAPVD1,DCAF8,FRMPD4,LONRF1,KIAA0586,BRINP1,GIT2,JAKMIP2,C8orf34,ZBTB24,MYEF2,CNIH3,MED24,RHOBTB1,WDR20,CCDC3,DLG3,DYNC1I1,DMTF1,ACOT8,ARRDC4,DTNB,DYRK1A,WDPCP,EDN3,CNNM1,SEMA3D,PHF20L1,GOLGA7,EPB41L1,ZNF549,RCSD1,FAM198B,ZSCAN30,TESK2,ZNF589,MED12L,GTF2IRD2,FHL1,FOXF2,AFF2,KHDRBS3,CELF1,NSG1,ADGRA1,HHIPL1,MPP6,GABRA1,GABRB3,GALR1,SIGLEC8,GCK,ALDH1L1,GGT5,PPARGC1A,ZNF276,GLYR1,PCDH11X,PRUNE2,NUDT21,GRIA1,GRIA2,DIDO1,GRM7,CLASRP,GSTT2,FAM107A,WIF1,HLF,ELOVL5,SYNPO,HMGCL,MSL1,GAREM2,LRRTM3,KCNA1,OLFM3,CDH20,KCNC2,KCNK1,KCNK2,KCNK3,STXBP5,LOC100128239,MAN2A2,ZFYVE27,SYT9,MITF,AFDN,MOG,COL28A1,PTOV1,MYO5A,ZC3H12B,NEFM,CCDC13,NF1,ALDH1L2,NTRK2,OXTR,KCNK10,PAK3,PCSK5,CDK18,PDE3B,DUSP26,CCSER2,PKD1,FAM216A,ST8SIA5,FTO,STRN3,ING3,POU6F1,PPM1B,CCDC144B,PPP3CA,PRKCZ,WBP1L,SNRK,CNTLN,PTPRD,PTPRG,PTPRH,RAB5B,CEP97,CCDC40,NWD1,RET,ERI2,RFX3,RIC8B,CYB561D1,CCDC25,ELP2,KIAA0895L,ACER3,NCBP3,AP1AR,SCP2,ASIC4,SUPT20H,RASA3,ITSN1,FERMT1,NTNG1,MAGI3,CHD9,FNDC3A,ST6GAL1,BCAN,DZIP1,SLC1A3,RPH3A,SEPHS1,SLC14A1,SLC20A2,ATF7IP,SORCS3,CDK5RAP2,SMARCD3,LIMCH1,RIMS1,SNRPN,UNC80,PDZD2,WDTC1,SP4,MYCBP2,KIF1B,NPAS3,NFASC,TAB2,SSTR1,ZC4H2,NKAIN2,ELOVL4,KANK1,ZC3H4,SYNE2,DNAJC9,SYP,C12orf76,ATP11A,KLHL4,TBX15,VWC2,ZFP90,CUX2,NAT16,OBSL1,SIRT1,ZFPM2,ITGB3BP,ACTR6,TNR,LILRA4,TPM2,CHST5,RGMB,SYNPO2,ZMYND8,RUSC1,LINC00689,PLEKHH2,MTCH1,LAT2,ZNF708,LYPD6,ZNF189,CA10,DNALI1,CSDE1,PCDH15,C12orf4,SMIM8,HNRNPA3,FBXO36,FAM219B,IFT88" MicroRNA hsa-miR-3159:mirSVR_highEffct hsa-miR-3159:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-105 9.63E-102 1.15E-104 1.06E-103 262 1056 "CPNE2,RALGAPA1,SDE2,KCNH8,KDM5D,NDRG3,ADD1,SORCS1,ERMN,PLEKHH1,OLMALINC,TXNDC16,LRRC7,OGT,LRCH2,CAPRIN2,ASPH,BRINP2,NUMB,ATM,SLC4A4,ATP6V1G2,DCAF5,BMPR1B,FUBP1,IL33,LURAP1,KALRN,PTBP2,VSTM2A,METTL6,SLC16A4,TMEM257,LRRFIP1,SRSF11,SOCS6,SYNPR,LSMEM2,IGFBP7-AS1,PLAA,CLTA,MAP4K4,LY86,CNTN1,AKAP6,RCHY1,RTTN,CHD1L,SLC35F1,ENTPD4,CRMP1,ANKRD44,SEC24C,ATRNL1,VCAN,CTNND1,PUM1,ZSCAN23,ARHGAP32,TOX,ZFYVE16,TBC1D5,MATR3,DAPK1,ELMO1,HP1BP3,COPS7A,CEP170,ALKBH8,SACS,NTM,EXOG,HS3ST4,DPYSL2,FAM78B,DNM1L,ABCC9,E2F5,FAM135B,EDNRB,ANKRD46,SEMA3D,TMTC1,FSD1L,FAM13A,KMT5B,ELN,PAN3,EIF1,VPS13B,EPS8,NCALD,CEP85L,MRPL37,ETV1,F5,F8,ZNF461,ZNF585B,FCGR1A,CEP78,KAT8,MED12L,FGF14,POLK,SUCO,TMEM107,SMC2,ATP2C1,STAU2,FYB1,DKK3,GABRB1,GABRG2,AHCYL1,DISC1,KIAA1841,SULT1C4,PPARGC1A,HPGDS,GNAL,GPR12,LPAR4,KIF3A,PSIP1,GUCY1A2,MAP4K5,GYG1,FRMD3,NCKAP1L,LINC01102,HLF,TCEAL6,IFI16,DISP2,IGSF1,SCIN,ZNF678,KIF2A,IPO5,STXBP5,KTN1,GPR155,MAP4,MARK1,MEF2C,MEIS1,SRSF12,ZNF680,MRPL42,RSPO2,MYCN,MYO9A,NAP1L2,NEK1,NEUROD1,NNAT,NODAL,SLC11A2,SETD4,CHAMP1,OPHN1,GLIPR1L2,ETFRF1,PDE3B,ENPP2,GPR85,SNX10,TMEM38A,PCDH18,MTRF1L,PURG,PMP2,TRHDE,ING3,FA2H,MAPK9,PTPRD,TMEM255A,RALGDS,SLC6A15,ZMAT4,RGS12,ZFHX4,CCDC82,TMLHE,CARF,TMEM100,RPL15,BAALC,RPL38,RYR3,SATB1,SCN2A,FNIP1,TNFRSF19,SOX6,NTNG1,MAGI3,SEC31A,SLC6A1,SLC8A1,BTBD7,SMARCE1,RIMS1,MYO16,SP4,MYCBP2,PBLD,CLASP2,NXT2,APOM,DIP2A,KLHL7,VPS13A,DDHD2,TAF9,CAMSAP2,CNTN2,SATB2,CUX2,TCF12,PCDHGB7,PCDHB6,PCDHB3,PUM2,USP32P1,FRYL,DICER1,ZFPM2,ZFP91,LRRC8A,NPL,TPM2,TRPC3,ANKRD20A2,ANO5,EIF4ENIF1,UBE3A,PITPNB,MEAF6,ZNF708,MICU3,TRIM9,ATP6V0E2,CRB2,ZNF177,FSTL5,DHX33,PRDM2,TMEM163,MPPE1,RGS7BP,AMN1,TRAM2-AS1,RNF170,VANGL2,SSPN,FRMD6,IFT88,NETO1,SLC4A10" MicroRNA hsa-miR-302c-3p.1:TargetScan hsa-miR-302c-3p.1 TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-373-3p:TargetScan hsa-miR-373-3p TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-520b:TargetScan hsa-miR-520b TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-302e:TargetScan hsa-miR-302e TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-520c-3p:TargetScan hsa-miR-520c-3p TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-520a-3p:TargetScan hsa-miR-520a-3p TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-520d-3p:TargetScan hsa-miR-520d-3p TargetScan 2.07E-105 1.16E-101 1.38E-104 1.27E-103 218 727 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-365:mirSVR_lowEffct hsa-miR-365:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.19E-105 1.23E-101 1.45E-104 1.34E-103 282 1221 "SERPINA3,ABAT,ASIC2,EMILIN3,ADAR,ADCY6,GALNT13,ADD2,SLC12A5,OGT,ANK2,SUGT1P4-STRA6LP-CCDC180,ALS2,DDO,USP37,SHROOM2,MIER1,ATP1A2,MTMR9,MPDZ,DNAJC27-AS1,MMD2,PTBP2,CANX,KRIT1,DCLK1,LARGE1,CDO1,TIGD7,CCPG1,IGFN1,TPP1,NMT2,FAM189A2,ABCG2,NIPBL,AKAP7,AKAP6,SLC25A27,COL9A1,SLC4A8,ABI3BP,SMARCAL1,ACBD5,TOGARAM2,CREM,ENTPD4,CREB5,GDA,LRIG1,FEZ2,SOCS5,CFAP61,RUBCN,HDAC4,TOX,ZNF337,KIAA0586,TMEM170A,BRINP1,SPATA2,JAKMIP2,TMEM130,USP3,MED12,DOCK2,DRP2,GNE,DNAJB6,EDNRA,EFNA3,RBM12,EGFR,ELAVL2,ELN,USPL1,DMTN,SRRM1,EPS8,CEP85L,SPEG,CDKL3,ETV1,ADGRV1,F3,F8,TUBB3,FCGR1A,FDFT1,TMEM164,POLK,SUCO,CAP2,C2orf88,EFCAB2,ATP2C1,MPP6,BRPF3,GALC,RAPGEF6,ARPP21,SIGLEC8,LRRC37A6P,MYOZ2,TUBGCP4,SESN1,NFU1,ZNF276,TOX3,MSL3,STARD3,POLL,LUZP2,GNAS,WDFY3-AS2,MCHR1,NR3C1,KIF3A,RABL2A,LINGO1,PSIP1,WIF1,ARHGAP36,HAPLN2,HPSE2,MSL1,METTL21A,KCNA1,KCNA4,KCNH2,KCNJ3,KCNK2,KHK,KIF5C,SMAD1,CHIC1,LRP1B,MIA2,POC1B,MOBP,MTTP,RSPO2,MYH6,ZNF862,BEX5,NCAM1,NFIA,NFE2L2,CNOT4,OCRL,OPCML,ZDHHC22,KCNK10,GLIPR1L2,SNTG1,PCMT1,PDE4D,PDYN,PFKFB4,SEMA5B,ZNF655,PLCL1,PURG,PRIMPOL,MAPKAP1,RC3H2,EXOSC10,SCHIP1,POLG,POU3F2,TATDN3,KANSL1,PRKACB,RELN,SLC22A23,GDPD2,MDGA2,BDNF-AS,EML5,PTPRN2,FAM120C,TMEM255A,PLEKHB2,OXR1,SLC6A15,ZYG11B,DPF2,RET,RFX4,ARHGEF10L,CCDC82,ALG9,ROBO1,KIRREL1,EPHA10,MAP6D1,ATAT1,SALL1,SEMA6D,SATB1,ATXN7,FAM19A1,ELMOD1,SOX6,CHD9,FNDC3A,SLC1A3,SLC2A5,BTBD3,RUFY2,SLC8A2,NAXD,ZFP1,CXXC4,OGDHL,SORCS3,INAVA,UNC80,SCN3B,TRERF1,KIF21B,KDM3A,ZSWIM8,PEG10,KIF1B,C11orf87,COLGALT2,ERBIN,NXT2,ELOVL4,CEP68,FAM168A,NUDT10,ADAMTS17,ANKRD12,ROBO3,ADGRL3,TMEM136,TBX15,VWC2,WASHC4,USP22,SYNE1,RALYL,OBSL1,PCDHAC2,USP32P1,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,ITGB3BP,AP4E1,BHLHB9,TLR4,TMPO,BEX4,R3HDM1,RASD2,SMUG1,PDSS1,STXBP4,LRTM2,UGT8,CCDC14,XRCC4,ZIC2,ZNF70,ZNF74,SPIRE1,EMSY,PCDH15,FIP1L1,C12orf4,UBE3B,KAT6A,ZNF248,IFT88" MicroRNA hsa-miR-144*:mirSVR_highEffct hsa-miR-144*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-105 1.54E-101 1.82E-104 1.67E-103 261 1050 "KDM5D,SLITRK1,OLMALINC,NLGN4X,SLC44A5,MTUS1,PCDH19,KCTD16,RTL9,TXNDC16,LRRC7,ALCAM,ARHGAP20,BBOX1,GOLGA7B,CDC42BPA,LRCH2,APAF1,APBB1,DDO,LGR5,MARCH3,NCOA1,ATP2A2,ALDH7A1,PROM1,SYNJ1,FUBP1,C5,RAB29,CALM1,KALRN,PTBP2,CAST,KRIT1,MTMR7,DLGAP1,TIGD7,CFL2,SRSF11,MS4A7,SYNPR,RAB33A,FBXO7,NIPBL,ARMC8,COL4A5,BTF3L4,CP,ENTPD4,HAPLN1,SNCAIP,LRIG1,SOCS5,PDE4DIP,NRSN1,BOC,DOCK4,HDAC9,DCT,C8orf34,HP1BP3,MAGI2,RHOBTB1,DLG2,EXOG,DRD1,DTNA,EDN1,FAM135B,EDNRA,FCF1,KLHL5,SH3GLB1,FAM13A,MRO,MBNL2,AASS,DMTN,EPHA5,ADGRV1,NRN1,CLVS1,ABCA8,FAM198B,ZNF585B,RPS6KC1,GORAB,FER,FGF13,SEMA4D,ATP13A4,ATP2C1,ST6GALNAC3,STAU2,NRG3,MEGF10,ARPP21,ERAP1,MTHFD2,SULT1C4,SPIN1,GLUL,PCDH11X,GNAO1,FERMT2,LNX1,GPD2,FUT10,EML4,RAPGEF4,ATP2B1-AS1,GRIA2,RABL2A,GUCY1B1,ZDHHC15,C2orf72,ZNF385B,LRRTM3,ITGAV,C2CD4C,KCNN2,LAMP2,STMN1,NCOA7,SMAD1,LYPLAL1,MBP,CHIC1,MDM4,LRP1B,MEST,AFDN,ZNF680,MTR,MXI1,NCAM2,NF1,NOVA1,NOVA2,NUCB2,GPR88,CHAMP1,OPHN1,PAK3,CNTN3,PCDH8,PCSK5,PCSK2,GPR85,CDK14,SEMA5B,CCSER2,PLCL1,PCDH18,HMGCLL1,TRHDE,RC3H2,SPATA6,EPB41L4B,DRAM2,MINDY2,PPP2R5E,PPP3CB,PRKACB,PKIA,PRKCB,GRAMD1C,HYDIN,RELN,STK32A,OCIAD1,PTPRN2,FAM120C,RAB5B,PID1,CEP97,SLC25A48,RAP1GDS1,RASGRF2,RDX,SLC6A15,ZYG11B,RET,ERI2,MORC4,GTDC1,RFX5,RIT2,RNASEL,ZFHX4,CCDC82,CARF,ATP8B4,TCP11L1,LRRK2,LGR4,KCNIP3,CSRNP3,SUPT20H,NLGN4Y,CHD9,WDR37,FAM81A,CCDC88A,INTS9,SMARCE1,RCOR3,TTC17,RIMS1,MBD5,CABCOCO1,RBM34,SON,MYT1L,TRERF1,ENKUR,UHRF1BP1L,SPP1,PEG10,CLASP2,ZC4H2,SS18,DIP2A,SYPL1,SYT4,TAF9,PDLIM2,UNC5D,WASHC4,PCDHB9,FRYL,CRB1,ITGB3BP,NPL,ZMYND8,FNDC5,TTPA,TMEFF2,VLDLR,WIPF1,NSD2,RICTOR,SF1,ZNF17,KCNT2,MKRN3,ANKS1B,SMARCAD1,WNK1,EMSY,ADAMTS9,HPS4,CIAPIN1,FIP1L1,SLC17A6,PARP11,KAT6A,ZNF248,PIANP,SENP7" MicroRNA hsa-miR-302a-3p:TargetScan hsa-miR-302a-3p TargetScan 2.82E-105 1.58E-101 1.86E-104 1.71E-103 218 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-372-3p:TargetScan hsa-miR-372-3p TargetScan 2.82E-105 1.58E-101 1.86E-104 1.71E-103 218 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-302b-3p:TargetScan hsa-miR-302b-3p TargetScan 2.82E-105 1.58E-101 1.86E-104 1.71E-103 218 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-302d-3p:TargetScan hsa-miR-302d-3p TargetScan 2.82E-105 1.58E-101 1.86E-104 1.71E-103 218 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-520e:TargetScan hsa-miR-520e TargetScan 2.82E-105 1.58E-101 1.86E-104 1.71E-103 218 728 "RNF150,PTCHD1,MTUS1,KCTD16,PARG,APBB2,APC,APOC2,LRRC4C,APP,ATP2B2,AZGP1,BCL7A,DCAF5,ARHGEF7,MTMR3,JAZF1,AP1M1,MYRF,CA12,FMNL3,CDC27,DLGAP2,CFL2,B4GALT6,KMT2C,ARMC8,LETMD1,AKAP5,RCHY1,IFFO1,ACBD5,CLOCK,C2CD2,CREB5,ARHGEF10,IPCEF1,FAM169A,NOS1AP,ARHGAP24,HDAC4,KIAA0513,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,HP1BP3,HS3ST4,CPEB2,DRD1,E2F5,EDNRB,HIPK3,FSD1L,EGFR,MBNL2,ABI2,PLXNC1,EIF5,ELAVL2,RGS17,C3orf18,PAN3,EPHA5,ANKRD13B,EPS8,ERBB4,ETV1,DNAJC27,EZH1,CORO2B,MED12L,CAMSAP1,POLK,MEX3B,FOXF2,AGAP2,FOXO3,FLT1,C2orf88,PDLIM5,ATP2C1,CELF1,MSANTD4,PHYHIPL,PCDH17,GNAL,GPM6A,GPR12,CECR2,ATE1,PTPRT,IL1RAPL1,KAT7,BVES,KLF12,MIER3,HLF,MSL1,C5orf24,SCRT2,ITPKB,KCNA1,CDH20,KCNB1,KCND2,LAMP2,HECTD2,NCOA7,MARK1,MBNL1,MEF2C,PPM1L,SAMD14,MXI1,MYCN,NELL2,NEUROD1,NFIA,NFYA,NNAT,PCBP3,NRCAM,OPCML,GPR137C,PAK3,PFKP,PKD1,PLCL1,PRRX1,POU6F1,KANSL1,PRKACB,PKN2,PROX1,PTPRD,PTPRG,RALGDS,FAT4,OXR1,ARID4A,RBBP6,RDX,GTDC1,KLHL11,ALG9,CYB561D1,CCDC25,RORB,RIMKLA,RPS6KA2,LGR4,RTN1,AMER2,SATB1,SBF1,ATXN1,SCN2A,HSPA4L,FAM102A,PPP1R9A,ARX,CPEB3,FBXO11,FNDC3A,CCDC88A,BTBD7,CPEB4,CMTR2,PALLD,MYT1L,KIF1B,IQSEC2,CDK19,NPAS3,LMO3,RGL1,FAM168A,ACSBG1,FGD4,CUX2,FAM189A1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,GPR161,AKTIP,ASXL3,DDHD1,NR2E1,RBFOX2,RGMB,NR2C2,FRRS1L,LYPD6,FSTL5,DPYSL5,LAMP5,CADM2,LRP8,RGMA,PARP6,PRDM8,PRDM10,PLSCR4,FAM13C,FZD3,MARCH8,KAT6A,CERS6,FAM219B" MicroRNA hsa-miR-1201:mirSVR_lowEffct hsa-miR-1201:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.87E-105 2.17E-101 2.55E-104 2.34E-103 269 1116 "RALGAPA1,SYS1,GALNT16,GALNT13,ADD1,RNF150,NLGN4X,HECW2,HFM1,SMIM17,ARHGAP20,PITPNM2,LCORL,USP28,APC,SHTN1,SHROOM2,SFMBT2,CAPRIN2,PCDHGB4,ZBTB10,TMEM108,ATP1A1,ATP2B1,RIPK1,TTLL9,ADAM15,BACH1,BCHE,KSR1,LINC00906,SCAPER,SGCE,NIPA1,CACNA2D1,CALM1,ISPD,SLC16A4,NEURL1,CDH8,LRRFIP1,EVI5L,LGI1,MAGI1,CCPG1,NRXN3,PCYT1B,ANKRD35,COL9A2,AKAP5,ABI3BP,AHCTF1,ZNF521,SLC35F1,ATRNL1,GREB1,PUM1,GPSM1,DCAF4,USP6NL,FAM131B,NOS1AP,KIAA0408,DCAF8,RIMS3,PITPNC1,ZBTB24,MYEF2,KIAA0753,BLOC1S6,SMG7,CCDC3,DNM1,DYRK1A,EDN1,SGK2,FRY,PHF20L1,TENM1,PLEKHA1,EPB41L2,EPHA5,IGSF6,TMEM132C,FDFT1,FER,MED12L,SPSB4,PRKAG2,SUCO,SYNCRIP,EVL,ANKFY1,DPYSL4,SORBS1,ERGIC3,NSG2,STAU2,AP4B1,MPP6,BRPF3,ZNF559,SEPT9,GPR162,USP19,TOX3,LUZP2,ADGRA3,FUT10,NUDT21,RAPGEF4,GRB10,GRID1,SPACA9,GRIN1,GRM1,GSTM5,GUCY1A2,WIF1,LINC01102,TLX1,TCEAL6,LINC00667,BRINP3,NME9,KCNJ9,KCNK2,KCNN2,IPO5,MOBP,MRPL42,MSR1,MXI1,NAP1L2,NDP,NELL2,NEUROD1,NEUROD2,NF1,SLC11A2,OPHN1,LOC100128398,PCDHGC3,PDE4D,GNG2,PIK3CD,SNX10,HMGCLL1,PNMA3,POLG,POU3F2,DRAM2,TMEM235,PPM1B,RAB39A,MAPK9,GRAMD1C,RELN,PIGG,SLC25A48,NWD1,RASGRF2,DBX2,BSDC1,RDX,GTDC1,UBR7,NUDT11,C12orf49,ALG9,ARMH4,ZC3H14,TCP11L1,ST6GALNAC6,AMER2,SATB1,LRRTM4,SCP2,ITSN1,FERMT1,NTNG1,SHMT2,CHD9,SEC31A,PAAF1,ABLIM3,ZNF365,SLC1A6,BTBD3,SMTN,WDR47,SLC6A1,SLC6A11,YPEL4,SEPHS1,CDK5RAP3,SLC12A2,SLC14A1,SCMH1,ZNF667,GKAP1,CDK5RAP2,IGSF9B,MBD5,BDP1,TSNAXIP1,ENKUR,IDI2-AS1,ZBTB43,NPAS3,DDN,NFASC,TAB2,ZSCAN29,ZC3H4,TMEM150C,DDHD2,MLST8,CAMSAP2,TBX15,VWA3A,ACSL6,SATB2,ZEB1,TPCN2,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB15,PCDHB7,ARHGEF12,CYB561A3,CRB1,NR2E1,RIMBP2,KCTD2,METTL3,SMUG1,TRO,TSN,TUB,ZKSCAN5,HIRA,UBE3A,LINC00689,CLIP2,ZIC1,KCNT2,POLR3H,EMSY,SCG2,PCDH15,C12orf4,HNRNPA3,NUP214,NLRP3,SLC4A10" MicroRNA hsa-miR-4265:mirSVR_lowEffct hsa-miR-4265:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.58E-105 2.57E-101 3.01E-104 2.77E-103 305 1423 "CPNE2,RALGAPA1,EMILIN3,FAM43B,FMNL2,GALNT16,DSCAML1,SLITRK1,ADORA1,ADORA3,GPR158,KCTD16,WDR35,PCDH10,MRTFA,LRFN1,ZFAT,ANK3,CNIH2,CNTNAP1,APBB1,FAM131A,KIAA1614,SEMA4G,MADD,DYNLL1,ADGRB2,BTK,IL33,KALRN,CAMK2D,TRIM41,RHBDL1,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,SYNPR,NRXN3,KIAA1549L,NMT2,CLTC,QKI,CNTFR,IQCK,SMARCAL1,PNKD,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,ARHGEF10,ATRNL1,CST3,SDC3,ARHGEF4,CFAP61,NRSN1,ECE2,BOC,MYADM,ZNF337,PHYHIP,IP6K1,DGCR5,ZEB2,HEPH,TIAM2,FBXL5,KIAA0753,SMG7,CD99L2,GNE,ARRDC4,TOM1,EDN1,EDNRB,CACNG7,YAF2,PHF20L1,APH1A,EGFR,GOLGA7,SORBS3,IRAK4,ELAVL4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,FLT1,NOP56,DPYSL4,CINP,KBTBD12,NEURL4,GABRA1,HRASLS5,BRPF3,B4GALNT1,SEPT9,ALDH1L1,TUBGCP4,KIRREL3,TTBK1,ZNF638,MAP7D2,POLL,GNAS,PRUNE2,STON1,MCHR1,GRID1,GRM1,RNF165,ADAMTS6,SCRG1,HMGCL,HNF4G,TLX1,OPALIN,DHX35,HSD17B1,CELF5,MYLK2,LRRC25,USP54,IL11RA,INSM1,C2CD4C,SLC35G1,KCNH2,KCNMA1,LIFR,SFXN5,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,MTTP,MYO5A,MYO7A,NCAM1,NUCB1,OPCML,CLDN11,OXTR,P2RY1,CDK18,PIK3CD,FAM218A,CCSER2,PLCB2,MAPKAP1,LRP12,PRRX1,SPATA6,PACSIN1,FA2H,FAT3,POLR2F,PPARA,PRODH,MASP1,RELN,SAMD9,LRRC49,SIDT1,WDR25,FAM120C,ZSCAN2,RALGDS,NWD1,RASGRF1,GTDC1,SEC61A2,RAVER2,CARF,KIRREL1,ROBO2,CCDC25,SNX22,SGSM1,PRR5L,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,ATAT1,KCNIP3,WLS,RYR3,LRFN5,SCP2,ASIC4,SELL,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,FERMT1,SHMT2,ST3GAL3,WDR37,LIMS2,KANSL3,PKNOX2,SLC6A8,SLC6A9,EFHD1,SLC20A2,LGI3,SMARCE1,RIMS1,KIF13A,SNRPN,FAM219A,TSNAXIP1,SOX15,CLUAP1,IQSEC2,CLSTN2,SMOC1,ZC4H2,SSPO,MAPK8IP3,SEPT3,GSE1,JMJD6,ARC,COBL,TACC1,MTCL1,MLST8,IQCE,TBX15,TCF7,TPCN2,CLASP1,SZT2,WDR7,SYNE1,CYB561A3,GALNT17,TMEM9,ERCC6L2,RIMBP2,TNFRSF1B,CABIN1,TPM4,WBP2,PRMT8,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,VAV2,NSD2,RICTOR,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,PLPP4,GPR158-AS1,NDRG4,ZBTB38,AMZ1,DPYSL5,PCBP1-AS1,DNALI1,LINC00632,RGS7BP,TMEM63C,CERS6,ZNF248,RNF170,SSPN,JPH3" MicroRNA hsa-miR-4253:mirSVR_lowEffct hsa-miR-4253:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.93E-105 2.77E-101 3.24E-104 2.98E-103 308 1450 "SDE2,ABR,AS3MT,CSMD2,ADCY6,GALNT13,SORCS1,USP31,PTCHD1,ADRA1D,ADRB2,SNX32,OSBPL6,PLA2G6,TAOK1,ALAD,SMIM17,GOLGA7B,FAM135A,ZFAT,ANK3,MYH7B,EPB41L5,UPRT,AMER3,CPNE5,ASTN1,CHID1,ATM,ATP1A3,SLC4A4,ATP2B1,ATP6V0A1,ADAM23,ADAM15,LINC00847,BCL2L2,KSR1,SYNJ2,MTMR2,BSN,LURAP1,TRIM41,RUNX1T1,KYAT1,AIFM1,CBFA2T2,EVI5L,CACNA2D2,ASIC3,CHN1,NDST3,NRXN3,FAM19A5,WHRN,RTTN,ACBD5,MYRIP,ZNF385A,CREM,HAPLN1,HINFP,NCOR1,SNCAIP,FEZ2,FEZ1,SUSD5,SOCS5,GREB1,CFAP61,NRSN1,BOC,PHF19,TBC1D5,IST1,ZEB2,ELMO1,CNIH3,ALKBH8,DLG2,DLG4,EXOG,ARRDC4,DYRK1A,KRBA2,E2F5,EBF1,FAM135B,EDN3,EDNRB,FSD1L,SIDT2,CELSR3,PHF20L1,SUGP2,EMX2,VPS13B,EPB41L2,LRRC17,SEZ6,ANKRD13B,SLC43A2,FAM198B,SCML2,OLFM1,FGF11,POLK,UBE2E3,FOXG1,PSD2,FLYWCH1,CINP,USP16,ERGIC3,SARAF,NRG3,HRASLS5,GABRG2,HBS1L,ERAP1,INPP5K,KIAA1841,GK,MSL3,DCLK2,WDFY3-AS2,GPM6B,RAPGEF4,RNF165,RNFT2,ATOH8,ELOVL5,GABARAPL2,HPCA,CPT1C,OPALIN,MSL1,ZNF546,IGFBP1,GAREM2,SCIN,IL11RA,ZNF385B,KCND3,KCNJ5,KCNJ10,KCNK1,KIF5C,A1BG-AS1,LIFR,SFXN5,LIMS1,NCOA7,LSS,MAG,MAN2A2,MAP4,MBNL1,ADAM11,MEST,MOG,CPNE9,SAMD5,MSR1,N6AMT1,MYO7A,SFR1,NEFH,NEK1,NHLH1,DNHD1,SLC11A2,IGSF11,BEST3,PFKFB4,ZNF655,FAM216A,PNMA3,SCHIP1,PRRX1,NECAB2,POU6F1,TATDN3,KANSL1,NKAIN4,RAB39A,SAMD9,WBP1L,QRICH1,WDR25,PTCH1,PTHLH,ZIK1,PTPRB,PTPRD,EML5,CASTOR1,PTPRH,FAM120C,TMEM231,USP47,RALGDS,SUSD4,ZNF493,VEPH1,DPF2,TTLL7,RNASEL,KIRREL1,SNX22,NEK11,EPHA10,RPL15,BAALC,TCP11L1,ATAT1,WLS,ZNF331,AP1AR,RMI1,DGLUCY,SATB1,SCN7A,ASIC4,SLC30A10,TRIM46,CASC3,ASAP3,FBXO11,PAAF1,SLA,SMTN,SLC6A9,SLC8A3,SLC11A1,KBTBD4,SLC20A2,SPHKAP,LGI3,NAXD,RCOR3,RIMS1,SNRPN,USP33,KIF21B,SOX10,LHFPL4,ZNF423,SPTAN1,IQSEC2,TSPYL2,LHPP,COLGALT2,ITPRID2,SAMSN1,EPB41L3,SSPO,NXT2,FCHO1,ZSCAN29,SEPT8,ADHFE1,KLHL7,ZC3H4,SYNE2,VPS13A,PLCB1,SYN2,PDLIM2,WSCD1,DMXL2,ZFP90,PHF24,PCDHB3,ZMAT3,TJP1,ERCC6L2,HEY2,DAAM2,KCTD2,TPM1,C9orf85,RGMB,SYNPO2,PDSS1,STXBP4,ZKSCAN5,HEPACAM,CADM1,PLEKHH2,ZNF709,MEAF6,TBC1D15,RBFOX3,SLC13A3,XRCC4,NDRG4,UPF3A,WNK1,CA10,PRDM2,GDPD5,ADAMTS9,NAV2,AMN1,PHTF2,ZNF248,FRMD6" MicroRNA hsa-miR-3130-3p:mirSVR_lowEffct hsa-miR-3130-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-105 2.97E-101 3.47E-104 3.20E-103 324 1595 "ACADM,NCKAP5,CSMD2,TMEM132B,GALNT16,SLC12A5,ADRA1D,BEND6,AP1B1,INTS2,PCDH10,AMPD2,CDC42BPA,DPP10,PHF12,CNIH2,API5,USP37,AQP4,SPTBN4,SLC4A4,ATP2A2,ADAM23,KSR1,BMP7,DST,SYNJ2,LINC00906,BTRC,HAP1,PTBP2,SLC25A14,BRSK2,HIP1R,ENTPD6,LRBA,SEPT7,CDH2,ZMYM4,NOG,COPB2,CHN2,MAP4K4,NIPBL,FAM149A,SUMF2,SEC31B,C2CD2,SH2B1,NCOR1,GDA,ABCG1,SNCAIP,CSF1,SEC24C,FEZ1,ATRNL1,VCAN,RASGEF1C,DZIP3,KIAA0040,RUBCN,USP6NL,FRMPD4,EARS2,TBC1D5,LIN54,DGKG,TOMM20,GIT2,SIRPA,C8orf34,TIAM2,MFAP3L,POM121,SMG7,KIF19,ARNT2,OLIG1,ECM2,ABCC5,EDNRB,HIPK3,FCF1,YAF2,SH3GLB1,CELSR3,TENM1,ELAVL4,EPB41L1,LRRC23,EPHA5,KCNMB2,ENPP6,ANKRD13B,SPEG,MRPL37,APC2,FKTN,MED12L,GTF2IRD2,FGF1,FGFR1,FOXG1,SYNCRIP,PSD2,DPYSL4,STAMBP,ARFGAP2,ATP6V1H,NSG1,STAU2,ADGRA1,ZNF44,ZMYND11,ERAP1,DISC1,GART,DNER,SULT1C4,GGTA1P,GGT5,RND1,DBF4,PCDH11X,GNAS,FERMT2,LILRB4,GPM6A,GPM6B,TMEM121B,GRIA1,ADAMTS13,ADAMTS8,CIT,ADAMTS6,HPS5,MIER3,HMGB1,ZNF491,NME9,C2CD4C,SLC35G1,KCNA4,CDH20,KCNA6,KCNK3,KIT,NAT8L,LOC100128239,MAN2A2,MARK1,MATN2,SYT9,PPM1L,MN1,MOBP,GIT1,COL28A1,MT3,MXI1,MYCN,MYO5A,NEFM,NFYA,NNAT,CNOT4,NTRK2,OCRL,OPCML,PCDH8,CDK18,PDPK1,HERC2P3,PIK3CD,PIK3R1,CCSER2,PLP1,HMGCLL1,SCHIP1,RETREG2,EPB41L4B,MED1,CRLS1,PTPA,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,RANBP3L,RASGEF1B,PRKACB,CEP41,HYDIN,GON4L,MDGA2,PSMD13,PIGG,CNTLN,PTAFR,PTPRG,C1orf109,NKAIN1,RAB5B,SLC25A48,ACSS3,IQSEC3,ZDHHC14,RET,ERI2,RGS7,TTLL7,SEC61A2,RNF220,PBRM1,RPRD1A,ZFHX4,ARMC5,RPE,SNX22,KIAA0895L,MCMBP,ADAL,STK32B,CNTNAP3,RTKN,TMEM156,CSRNP3,ATXN2,HOGA1,SCN2B,SCP2,SH3GL2,PPM1E,FERMT1,CPEB3,HKDC1,SLITRK3,BTBD3,KANSL3,LRRC55,SLC6A7,SLC6A8,SEPHS1,ARHGEF40,BTBD7,TET1,CDK5RAP2,SMARCE1,MAPKBP1,SNRPN,TMCC1,WDTC1,TNIK,FNBP1,ZSWIM8,SP4,NMNAT2,KDM4C,IDI2-AS1,PEG10,KIF1B,RAP1GAP2,PHLDB1,ZC3H4,DNAJC9,SYP,POPDC3,MLST8,CNTN2,TCF7,CLASP1,NAT16,DOCK9,PHF24,SLC19A3,OBSL1,FRYL,SIK3,ATP13A2,SIRT1,SPX,ITGB3BP,HHIP,ARL10,TIAM1,NR2E1,RIMBP2,LILRA4,RASD2,TPM1,TPM2,C9orf85,CHST5,ELP5,PDSS1,TRO,TRPC1,HIRA,AMOT,PLEKHH2,ZNF709,MTCH1,LMF1,LGI4,ZNF711,CFAP52,SLC26A10,MKRN3,LYPD6,DPYSL5,ZXDA,SLC38A1,RNF103,HPS4,PDSS2,ST7,SMIM8,FBXO36,ADAMTSL3,ZDHHC20,PIANP,FRMD6,SENP7" MicroRNA hsa-miR-376b:mirSVR_highEffct hsa-miR-376b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.26E-104 7.09E-101 8.26E-104 7.61E-103 279 1204 "NCKAP5,TMEM132B,DSCAML1,PWWP2A,PTCHD1,INTS2,NME5,OSBPL8,HFM1,PCDH10,LRCH2,ANK2,APC,ALS2,LGR5,TMEM263,ZFYVE28,MARCH3,ASPH,ATP2A2,ATP2B1,ADGRB2,SNAI3-AS1,BARD1,DCAF5,PROM1,SCAPER,MTMR3,CACNA1G,CA8,LURAP1,SLC25A14,VXN,SYT6,CH25H,RUNX1T1,MTMR7,INA,SLC16A4,LRBA,SEPT7,CDC42,CDO1,SRSF11,PPT2,NRXN1,QKI,NIPBL,BTF3L4,ABI3BP,MFSD4A,HS3ST5,CP,FAM171B,HAPLN1,ANKRD44,CSNK1G3,ATRNL1,PDE4DIP,RIMS2,EDRF1,HDAC9,GAPVD1,LIN54,IP6K1,MYEF2,COPS7A,ALKBH8,WDR20,EXOG,DNAH9,DPP6,ECM2,ABCC9,E2F5,WDPCP,EDN1,FAM135B,RASGRP1,TMTC1,SIDT2,ELAVL2,EML1,DCTN4,EPB41,EPHA5,RABEPK,SRRM1,PRMT5,SLC9B2,POLR1B,POLK,ATP2C1,KHDRBS3,ST6GALNAC3,NSG1,PHYHIPL,MEGF11,GABRA2,GALNT15,HBS1L,ZMYND11,ZNF559,SULT1C4,ADAM28,MALT1,TOX3,CBX1,FERMT2,WDFY3-AS2,PSRC1,CNTRL,GRIA4,GRIK2,GRIK5,NR3C1,CLASRP,HAS2,MIER3,HNF4G,SMAP1,SCIN,ITPKB,METTL21A,OLFM3,KCNC2,KCNH2,STXBP5,LAMP2,LIG4,PAXBP1,PIK3AP1,MBD1,MDM4,POC1B,MMP16,CD200,GIT1,LAYN,MYO9A,NCAM2,ALDH1L2,CNOT4,NUCB2,OPHN1,PAK3,DPY19L2P2,PDE3B,PDE4B,PDGFRA,SLC10A4,OLA1,FAM218A,CCSER2,SNX10,NLE1,PMP2,LRP12,ING3,SPATA6,MED1,PPP2R5E,PPP3CB,PRKACB,CEP41,PKN2,MASP1,VPS13C,PSMD13,PTHLH,ELOVL2,SPDL1,STK32A,PTPN13,OCIAD1,ZNF615,RAB5B,USP47,ARID4A,GAL3ST4,SLC6A15,ZYG11B,ERI2,RFX4,RGS3,SETD5,TMLHE,CARF,ROBO1,RORB,ELP2,TMEM100,NEK11,EPHA10,ZNF671,KCNIP1,AP1AR,SALL1,MIR124-2HG,SLC30A10,COPZ1,FERMT1,DOCK10,SHC4,CHD9,FBXO11,SLC6A1,CCDC88A,TET1,MAST1,SORCS3,CDK5RAP2,MYH15,RCOR3,IFT122,RIMS1,MBD5,UNC80,MYCBP2,SPP1,KDM4C,IDI2-AS1,CDK19,SPART,TAB2,ITPRID2,LARP4,NKAIN2,ARHGEF9,ANKRD28,SYT4,AGTPBP1,TBCEL,CUX2,PCDHB9,FAM200B,AP4E1,TIAM1,TJP1,ASXL3,CABIN1,RBFOX2,TPD52,PRMT8,ELP5,TRIO,ZMYND8,KCNE5,RFTN2,TMEFF2,UGT8,VLDLR,VSNL1,WIPF1,ZIC3,KCNT2,CELF4,ZNF189,ANKS1B,SMARCAD1,DHX33,ZNF225,SLC30A3,SLC30A4,CSDE1,EVI5,RNF103,SCG2,NAV3,PPP1R3F,SLC17A6,PARP11,FZD3,PAK5,PHTF2,ADAMTSL3,JMJD1C,IFT88,JPH3" MicroRNA hsa-miR-101-3p.1:TargetScan hsa-miR-101-3p.1 TargetScan 1.30E-104 7.33E-101 8.53E-104 7.86E-103 209 671 "ASIC1,ARID1A,ELFN2,ADCY5,ADCY6,CCDC85A,AXIN2,PTCHD1,OSBPL1A,PCDH10,BEGAIN,OGT,DPP10,LRCH2,ANK3,PPFIA4,PPFIA1,APC,APP,MARCH3,DACT3,DDX3Y,ATP2B2,CDK5R1,MTMR2,JAZF1,LDLRAD4,CACNB2,CAMK2D,CAMK2G,BRSK2,CBFA2T2,C1orf52,LONRF2,CDH8,MAGI1,NOG,DLGAP3,CLCN3,QKI,MYRIP,HAPLN1,ANKRD44,PPP1R16B,APPL1,CCDC144A,PYGO1,HDAC9,LONRF1,JAKMIP2,MAGI2,G3BP2,MTX3,RAB39B,DMD,NR1D2,CPEB2,DRP2,DYRK1A,ABCC5,EBF1,HIPK3,FEM1B,PHF20L1,MBNL2,ABI2,EIF4G2,RGS17,ELN,EPB41L1,MTSS1L,EPHA5,ERBB4,ETV1,EYA1,DLC1,FGFR3,MEX3B,PSD2,ATP2C1,DOT1L,GAB1,ARPP21,FAXC,GFRA1,GLI2,RAB30,PTPN5,KAT7,FAM222A,HAS2,KLF12,BACH2,NEGR1,AGFG1,JAK2,KCNA1,KCND3,KCNN3,KIF2A,KIT,IPO5,LIFR,PACRG,NAT8L,MARK1,MBNL1,MDM4,MEIS2,KITLG,MITF,MSI1,JAKMIP3,RSPO2,MYCN,NACA,NAP1L1,NEUROD1,NOVA1,NPTX1,CLDN11,PAK3,CNTN3,PCDH8,PCSK5,CDK18,PDE4A,PDE4D,ENPP2,GPR85,PIK3C2A,PCDH18,LRP12,PRRX1,FA2H,FAT3,PPP2R5E,PROX1,PTCH1,MARCH1,FAT4,RASGRF1,KHDRBS2,REV3L,FIGN,RFX3,NUDT11,PBRM1,ROBO2,FBXW7,RYR3,SALL1,ATXN1,SCN2A,SCN8A,CPEB3,MAGI3,FNDC3A,BTBD3,EPN2,ATF7IP,CXXC4,FAM126B,SCN3B,KDM3A,ARHGAP26,LMO3,C11orf87,POGZ,LRRC4,AJAP1,GSE1,FAM168A,PRRC2C,ADAMTS17,PLCB1,ANKRD28,ANKRD12,MCF2L,CAMSAP2,PDLIM2,FBXW11,MGRN1,DMXL2,PSD3,NSD1,PUM2,FRYL,NACC2,ASXL3,DDHD1,HEY2,RIMBP2,KAT6B,RASD2,CADM1,PITPNB,FLRT2,KCNK12,PCDH20,NDRG4,RGMA,GDPD5,NAV3,HNRNPA3,CERS6,ADAMTSL3,ADAMTS10,NETO2" MicroRNA hsa-miR-3185:mirSVR_highEffct hsa-miR-3185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-104 7.46E-101 8.67E-104 7.99E-103 289 1289 "RALGAPA1,SERPINA3,ACLY,C3orf14,CSMD3,DSCAML1,SORCS1,BEND6,DPY19L2P4,SLC44A5,GPR158,HECW2,HFM1,LRRC7,ZFAT,LCORL,PHF12,CNIH2,MIER1,TMEFF1,ARRB1,ARRB2,CADPS,CAPRIN2,RIPK1,TTLL9,ZNF599,JAZF1,CA4,KALRN,PTBP2,CAMK2D,SPAG9,CBR1,CCKBR,MTMR7,LRBA,ZMYM4,LOC730101,TIGD7,CHN1,CASC2,SYNPR,KMT2C,RAB33A,NRXN1,NRXN2,TPP1,NIPBL,CNGA3,CNR1,IQCK,COL9A1,SMARCAL1,CNRIP1,MFSD4A,CPS1,FAM171B,SEC31B,CREM,LRIG1,CSNK1G3,PDE4DIP,CTH,CTNND1,RIMS2,ZSCAN23,CYBB,GPRASP1,TOX,PABPC5,ARMCX4,C8orf34,DGCR5,ZEB2,ELMO1,CEP170,PLPPR4,SPOCK3,CCDC3,DLG2,CPEB2,DPP6,DTNA,DNAJB6,GOLT1B,E2F5,WDPCP,EDNRB,PHF20L1,RASA4,KCTD3,TNK2,ELAVL4,EN2,OLIG2,ENO2,EPB41L2,EPHB1,SRRM1,DENND4A,ZNF461,FABP7,EFEMP1,GTF2IRD2,FGF12,FGF14,CAP2,IP6K2,AGAP2,JKAMP,NBEA,APOPT1,PDLIM5,ERGIC3,CELF1,STAU2,TBR1,DKK3,AHCYL1,JPH4,IP6K3,GART,DNER,MYOZ2,PCDH17,GLS,STARD3,GNAL,GNAS,PSRC1,GPR22,EML4,RAPGEF4,GRID1,ADAMTS8,GRM7,ZNF496,MFSD2A,LINGO1,FAM107A,IGSF21,HSPA1L,NKD1,KIAA1755,USP54,SCIN,ZNF385B,LAMP2,LMO1,MAN2A2,MAOB,IL17D,MEIS2,AFDN,XRRA1,CD200,ZNF680,GIT1,MYCN,MYO7A,NEFH,NF1,NHLH1,NTRK2,IGSF11,GPR88,OXTR,PAK3,DPY19L2P2,PCMT1,PCSK1,PDE1A,PDE1C,PFKFB2,CDK14,GDAP1L1,ANLN,STRN3,PRRX1,SEPT4,EPB41L4B,PPM1B,CRLS1,PPP3CA,KANSL1,PKN2,MAPK10,PRPSAP2,PIGG,CNTLN,STK32A,PTPRE,MARCH1,RAD51D,ZNF493,RASGRF1,KHDRBS2,MSANTD2,ZYG11B,MORC4,RFX3,KCTD17,RIC8B,CCDC102B,UEVLD,PRR5L,MEG3,HSD11B1L,KCNIP1,RTN1,FOXRED2,SALL1,SATB1,FAM19A1,SCP2,ITSN1,CPEB3,MAGI3,FNDC3A,R3HDM2,CCDC92,NUBPL,PAAF1,SLA,ZNF365,FAM81A,RUFY2,LRRC55,SLC6A8,SLC11A1,RCOR3,TTC17,TRERF1,SP2,CLUAP1,HECW1,ZC3H13,SPTAN1,NPAS3,LMO3,C11orf87,CLASP2,SST,NUDT10,DDHD2,FBXW11,ANO4,TPCN2,PCDHGB7,USP32P1,FRYL,TF,SIRT1,MTMR14,TMEM9,NR2E1,TMPO,R3HDM1,TNR,ZNF384,FNDC5,RUSC1,LINC00689,BEST1,GUSBP1,SLC13A3,ZBTB14,PLPP4,NDRG4,LYPD6,ZNF184,LAMP5,PLPPR5,MFF,LRP8,SLC38A1,PRDM10,TMEM178A,SEMA3B,NAV3,FAM47E,DOCK8,UBE3B,MSRB3,NHSL1,PIANP,FXR1,FRMD6" MicroRNA hsa-miR-1283:PITA hsa-miR-1283:PITA_TOP PITA 1.56E-104 8.74E-101 1.02E-103 9.35E-103 204 638 "RALGAPA1,ADD1,SORCS1,PWWP2A,NLGN4X,INTS2,MTUS1,HECW2,PCDH19,OSBPL8,LRRC7,SRPX,UNC79,LRCH2,SEMA4G,SLC4A4,ATP2B1,JAZF1,CALM1,CH25H,MAP7,LRBA,CDH2,ZMYM4,CHN1,SYNPR,NRXN3,FAM19A5,QKI,AHCTF1,SLC35F1,CRHBP,SIPA1L1,SOCS5,CNTNAP2,PLCXD3,PUM1,ST18,KIAA0408,HDAC4,TOX,MATR3,MAML1,DAPK1,DNAJC6,HP1BP3,SNAP91,G3BP2,DLG2,DYNC1I1,CDON,CPEB2,GOLT1B,EDNRA,PHC2,FRY,APH1A,MBNL2,EGR3,EIF4G2,COPS4,RGS17,WAC,TESK2,UBE2E3,MEX3B,FOXO3,ANKFY1,NBEA,FUT9,OGA,MEGF10,GABRB3,SALL3,PPARGC1A,RNPS1,SPIN1,TNRC6A,GLUL,GNAO1,GPM6A,STON1,GPR37,GRM3,IL1RAPL1,ZBTB49,PSIP1,KLF12,MIER3,HMGCR,AGBL5,NEGR1,IGF1,ZIC5,BRINP3,SLC6A17,KCNA1,KCNK1,KCNMA1,STXBP5,LIFR,NAT8L,CHIC1,LRP1B,MEF2C,CD200,SESN3,HS6ST3,MYO5A,NEXMIF,PABPC1L2A,HNRNPM,NCAM1,NFIA,PDE4D,MAPKAP1,PRRX1,FAT3,MINDY2,PPP2R5E,PPP3CA,PKN2,DIRAS2,PRPSAP2,PTCH1,ELOVL2,PTK2,PTN,PTPRB,FAM120C,PTPRZ1,USP47,OXR1,BSDC1,RDX,RFX3,UBR7,RGS7,NUDT11,ZFHX4,RORB,ARMH4,FBXW7,SOX8,NCBP3,SATB1,ATXN1,ATXN2,SCN3A,SOX6,CASC3,NLGN4Y,PPM1E,SLITRK3,SLC1A3,BTBD3,WDR47,SEPHS1,CCDC88A,CPEB4,SNAP25,PDZRN3,MYO16,SOX1,MYT1L,SOX11,SP4,PEG10,SRPK2,SMOC1,SYT1,TAL1,CNTN2,TCF4,DMXL2,TCF7L2,SZT2,SIRT1,AKTIP,SLC44A1,ERCC6L2,KAT6B,RBFOX2,TPD52L2,TPM1,TPM3,TRPS1,CADM1,UBE3A,UBTF,SLAIN1,TBC1D15,ZIC3,FMN2,CELF4,WNK1,NAV3,FZD3,HNRNPA3,CERS6,JMJD1C,MSRB3,SOCS4,SENP7" MicroRNA hsa-miR-298:mirSVR_highEffct hsa-miR-298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.70E-104 9.52E-101 1.10E-103 1.02E-102 278 1197 "ACTN1,CSMD3,NDRG3,NDRG2,CCDC85A,ADD1,PTCHD1,SLC44A5,ZNF608,HECW2,LRRC7,ALCAM,ARHGAP20,LTBP4,ANK2,SEMA7A,PARG,APP,MIER1,MADD,ARNTL,NCOA1,DYNLL1,NOL4,ATP6V1G2,BARD1,MPDZ,ST3GAL5,ARHGEF7,CDK5R2,CA8,PTBP2,CAMK2D,CAST,KRIT1,INA,TMEM257,ARHGEF2,REPS2,CDH8,CDH18,L3MBTL4,DLGAP1,SRSF11,SYNPR,SLIT2,KMT2C,TPP1,CNTN1,LETMD1,SLC4A8,TOGARAM2,HS3ST5,FAM171B,CREM,RGS6,MICAL2,OSBPL3,ATRNL1,SOCS5,PDE4DIP,CTNND1,CX3CR1,CYBB,RIPOR2,MATR3,IST1,DCTN1,ZEB2,MYEF2,RHOBTB1,PLPPR4,SV2B,SPOCK3,G3BP2,CCDC3,ZNF582-AS1,DLG4,HS3ST4,USP3,CPEB2,DTNA,DYRK1A,EDNRA,SGK2,EGFR,EIF4G2,COPS4,TENM1,ELAVL2,TMEM35A,RABEPK,CEP85L,ADGRV1,F5,PRMT5,TESK2,SLC9B2,KIAA1109,POLR1B,FGF13,FHL1,SUCO,CAP2,TMEM107,PDLIM5,STAMBP,CAMKK2,ATP2C1,ST6GALNAC3,CSPG5,NSG1,AP4B1,MPP6,PHYHIPL,ZMAT1,HRASLS5,GABRB1,CAB39,ZMYND11,IP6K3,WASF3,GATM,MSTN,PPARGC1A,GLI2,RAB30,INSM2,KCNMB4,ZNF782,DIPK1C,FUT10,STON1,LPAR4,GRIA2,SPACA9,PRDM5,RNFT2,SLC2A6,IRAK3,ARHGAP36,MIER3,VSIG4,ZDHHC15,OPALIN,LRRCC1,IGSF1,ZNF678,ZNF385B,NME9,KCNA2,KCNC1,KCNC2,KCNN2,FGFBP3,ZNF667-AS1,MAP4,MATN3,MBNL1,MEIS1,CD200,CPNE9,COMMD5,MYBPC1,MYO9A,BEX5,SLC11A2,HCN1,NTRK2,NUCB2,OGG1,OPA1,PCDH9,PCMT1,PDE4B,HERC2P3,ABCB1,FAM218A,KCTD15,EXOSC10,SPATA6,MED1,CEP41,EPDR1,GRAMD1C,PRPSAP2,SAMD9,GDPD2,SNRK,ELOVL2,PTPRG,FAM66C,NWD1,DPF2,MORC4,PRIMA1,LGI2,CARF,ELP2,ACER3,TCP11L1,SYNDIG1,WLS,AP1AR,SCN2A,FAM19A1,CASC3,TRA2B,SH3GL2,FERMT1,NTNG1,MAGI3,FBXO11,CCDC92,PAAF1,ZNF365,SLC1A6,PPP4R3A,ATF7IP,SORCS3,MYH15,SMARCE1,RCOR3,IFT122,ANKRD36,MBD5,PDZRN3,WDTC1,KDM4C,C11orf87,CLASP2,CLSTN2,POGZ,NKAIN2,ELOVL4,RGL1,GANAB,SYNE2,SEMA4A,AGTPBP1,TBCEL,FBXW11,TBX15,ZEB1,RPGRIP1L,TCF12,PCDHB4,AKNA,GPRIN3,TEX15,FAM200B,DICER1,ITGB3BP,MTMR14,ACTR6,DDHD1,TMOD1,TPM1,RUSC1,KCNE5,SF1,ZFP37,PLPP4,ZNF138,AMZ1,SH3GLB2,PLPPR5,SMARCAD1,DNALI1,LRP8,STOX2,KCNAB1,RGS7BP,RTN4,FRMD6,NETO2,FAM198A,SPATA13" MicroRNA hsa-miR-889:mirSVR_highEffct hsa-miR-889:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.07E-104 1.16E-100 1.35E-103 1.24E-102 292 1317 "SDE2,ACTN1,ADORA3,BEND6,MTUS1,TXNDC16,HFM1,TAOK1,BCAR3,ABCD2,PCDH10,FAM135A,OGT,DPP10,UPRT,PPP4R4,NUMB,DDX3Y,ATP2B3,B3GALT2,ADAM23,BCHE,DCAF5,BMPR1B,DST,C5,CALB1,PTBP2,CANX,KRIT1,MTMR7,DGKI,LGI1,DLGAP1,ADGRG1,SRSF11,IGFBP7-AS1,FAM149A,BTF3L4,AKAP5,SLC4A7,SLC4A8,GDA,TRIM69,OSBPL3,ATRNL1,ERC2,APPL1,NRSN1,USP6NL,KIAA0408,DOCK4,FGFR1OP2,ZFYVE16,KCTD8,ARMCX4,DCC,SPATA2,ZNF804A,HP1BP3,BLOC1S6,ALKBH8,WDR20,DLG2,HS3ST2,ABI1,PDCD6IP,DSCAM,DNAJB6,ABCC5,DNM1L,ABCC9,EDIL3,EDN1,TMTC1,FAM13A,PHF20L1,EIF4G2,PLEKHA1,DCTN4,VPS13B,GPHN,ADGRV1,F5,RPS6KC1,ZIC4,FCGRT,KIAA1109,FGF12,CAMSAP1,MEX3B,ATP13A4,TRMO,SMC2,UFM1,DACH2,NSG1,FYB1,GABRA1,TRAF3IP2,DENND2A,GALC,JPH4,ARPP21,ZNF234,ZNF274,NCKAP1,SESN1,GLS,GLUL,LUZP2,KCNMB4,RAB40B,GPR22,AP4S1,GYG1,IRAK3,ATXN2L,ARHGAP36,MIER3,VSIG4,NEGR1,DHX35,HTR2A,INSM1,ITGAV,KCNJ3,KCNJ16,KCNMA1,HECTD2,ARHGAP12,PIK3AP1,MATN3,MBNL1,EFHB,SRSF12,MIA2,MITF,MOBP,ERICH3,CCDC80,MSR1,MYCN,PABPC1L2A,NAP1L1,NCAM2,NF1,NFE2L2,CNOT4,PCBP3,SLC11A2,NRCAM,OPA1,P2RY1,GLIPR1L2,PCDH9,PCMT1,PCSK1,PDGFRA,ZNF655,XRN1,FAM216A,PLCL1,PLP1,PCDH18,HMGCLL1,MAPKAP1,RC3H2,EPB41L4B,SLC36A4,POU3F2,MINDY2,PPP2R5E,PPP3CB,PRKACB,PRKCZ,DIRAS2,SAMD9,SLC22A23,CNTLN,MTMR10,PTHLH,TMEM260,PTPRB,PTPRD,PTPRG,PPP2R3C,PLEKHB2,ZNF793,RAP1GDS1,ARID4A,KHDRBS2,ERI2,GTDC1,UBR7,TTLL7,PBRM1,SETD5,PCMTD2,MCMBP,ATP8B4,RPL38,ZNF568,ZNF331,SEMA6D,LINC00461,SELL,HSPA4L,SH3GL3,DOCK10,NTNG1,MAGI3,CNKSR2,FAM81A,PPP4R3A,EPN2,SLC6A1,SLC6A11,CCDC88A,SLC12A2,SLC14A1,SORCS3,RIMS1,PDZRN3,UNC80,RBM34,USP33,FAM219A,PDZD2,SPP1,C11orf87,ITPRID2,NEK4,TTBK2,VPS13A,ASTN2,TAF9,CAMSAP2,FBXW11,TBL1X,TBX15,TCEA1,EHBP1,SATB2,CUX2,SZT2,SYNE1,PCDHB9,PCDHB6,USP32P1,SLC35G2,SIK3,ZFPM2,TGFBR3,HHIP,ASXL3,ERCC6L2,TNS1,RUNDC3B,AMACR,TSC1,TTC3,TMEFF2,CADM1,EIF4ENIF1,USP1,VSNL1,WNT7A,RICTOR,ZIC1,ZNF540,TCEAL7,ZBTB38,SMARCAD1,WNK1,EMSY,STOX2,PCDH15,NAV2,WNK3,SLC17A6,HRASLS,FAM13C,PHTF2,JMJD1C,TRAM2-AS1,KLHDC1,NETO2,NETO1,DPF3,RNF146,GAN" MicroRNA hsa-miR-3144-3p:mirSVR_lowEffct hsa-miR-3144-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.11E-104 1.19E-100 1.37E-103 1.26E-102 275 1173 "ACADM,CSMD2,XKR4,FMNL2,ADD1,CDC7,ESYT2,OSBPL1A,BCAR3,ABCD2,ARHGAP20,FAM135A,ANK3,MAP4K3,USP28,PARG,ARHGAP5,NUMB,ATP2B2,NOL4,BBS2,SEC11C,BCHE,KSR1,BMP7,GPC2,HAP1,KYAT1,LDB2,REPS2,LRRFIP1,MAGI1,KIAA1549L,SLC4A7,ZFP28,PREPL,HAPLN1,SNCAIP,TENM4,VAC14-AS1,APPL1,PHF14,CTNND1,DCAF4,CCDC144A,CYBB,DOCK4,HDAC9,TCAF1,RIPOR2,FRMPD4,ZFYVE16,MATR3,KIAA0586,KCTD8,DGKG,TOMM20,YTHDC1,ZNF804A,TIAM2,KIAA0319,ZC3H11A,RHOBTB1,SNAP91,DLG2,CASP8AP2,RCAN1,DTNA,ECM2,DYRK1A,HIPK3,FCF1,RASGRP1,PHF20L1,APH1A,MBNL2,ABI2,EIF5,ELAVL2,ELAVL4,EFS,MRPL10,ZNF585B,SH3YL1,TAOK3,EFEMP1,ATP8A1,CEP78,FECH,HPCAL4,FOXG1,SYNCRIP,FOLH1,C2orf88,PDLIM5,ATP2C1,ZNF605,ST6GALNAC3,SARAF,TMEM151A,ABLIM2,ZNF512,DKK3,HBS1L,BRPF3,DISC1,MSTN,ADAM28,GLS,PCDH11X,ADGRA3,TDRKH,NUDT21,GRB10,GRIA1,GRIA4,PRDM5,GRM5,GRM7,CIT,RNF165,WIF1,MAEL,RASSF8,ICA1,ZIC5,RBPJ,DOCK7,ITGAV,METTL21A,KIF5C,STXBP5,INSYN2,LIMS1,PIK3AP1,MAOB,SYT9,CHIC1,SRSF12,MEST,KCTD6,MIA2,POC1B,MMP16,SAMD5,C10orf105,MYO5A,FXYD6,NCAM1,NF1,DNHD1,NTRK2,LOC100128398,PAK3,PCSK1,PRTG,PDE1C,GPR85,GNG2,SERPINI1,ZNF655,SNX10,CDIP1,PRRX1,MAGEL2,EPB41L4B,MED1,CRLS1,HYDIN,SAMD9,TMEM104,CNTLN,ANKHD1,UHRF1BP1,MTMR10,PXK,PTPRB,C1orf109,ZNF493,ARID4A,SLC6A15,REV3L,SLC25A36,NUDT11,CCDC82,TMLHE,ALG9,RPE65,BAALC,SPIN3,MCMBP,ACER3,RMI1,SCN2B,LINC00461,TNFRSF19,PEAR1,SFPQ,SCAF8,KIF21A,PPM1E,KIF16B,SHMT2,FBXO11,FNDC3A,R3HDM2,SEC31A,WDR37,FAM81A,PPP4R3A,SLC8A3,SLC12A2,SLC15A2,ELMO2,SLCO1A2,SLIT1,ANKRD36,LIMCH1,MBD5,SNRPN,UNC80,SOX2,SP2,C11orf87,CLASP2,POGZ,SAMSN1,ZSCAN29,ELOVL4,CEP68,SYT11,SYNE2,VPS13A,SYT4,PJA1,FAM208A,ALG1,FBXW11,TRIM2,TCF12,ARHGEF12,FRYL,CCDC173,TEX15,DICER1,ITGB3BP,GPR161,ZNF106,AKTIP,DDHD1,ERCC6L2,TPM1,C9orf85,RGMB,ELP5,ANO5,SSBP2,TMEFF2,FAM155A,ZBTB14,ZNF74,LYPD6,POLR3H,ANKS1B,CADM2,SLC38A1,EVI5,STOX2,NAV3,URM1,HNRNPA3,PHTF2,JMJD1C,SNX14,NETO2" MicroRNA hsa-miR-106a*:mirSVR_highEffct hsa-miR-106a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-104 1.28E-100 1.48E-103 1.37E-102 261 1059 "RALGAPA1,CLK4,ARID1A,CCDC85A,ADD3,SLC12A5,SORCS1,ADGRF5,SPARCL1,AMT,CDC42BPA,LRCH2,USP28,ALS2,BCAS1,MIER1,ZFYVE28,CADPS,NCOA1,NUMB,ASTN1,ATM,ATP1A2,SLC4A4,EIF4G3,ZNF583,DPY19L3,ADAM23,ADGRB3,MPDZ,SEC11C,ZNF599,PROM1,BMP7,DST,FUBP1,JAZF1,IL33,PTBP2,CAST,LDB2,CDH2,LRRFIP1,MAGI1,B4GALT6,RAB28,CLCN3,TJP2,QKI,IQCK,AKAP6,SLC4A8,ABI3BP,LRRC3B,ARHGEF10,ATRNL1,SIPA1L1,PDE4DIP,KIAA0040,GREB1,ST18,HDAC9,DGKB,DAPK1,C8orf34,SPOCK3,SEC16A,CPEB2,DTNB,ABCC5,ABCC9,GOLT1B,E2F6,HIPK3,FAM13A,PHF20L1,SUGP2,ELAVL2,PLEKHA1,ELAVL4,C8orf37,EN2,SRRM1,EYA1,WAC,TMEM132C,ATP8A1,FCGR3A,TOMM40L,SEC24B,KIAA1109,BAIAP2,MEX3B,SLC37A3,SORBS1,TMEM107,FAM49B,GABBR1,GALNT15,DISC1,ACSS1,ARFIP1,GGT7,PPARGC1A,TXNL4A,COPS8,GLRB,MSL3,ZNF638,GOLGB1,GRIA2,GRIA4,GRIN2D,GRM1,RNF165,HMGB1,MSL1,IDH3A,TUBB2B,KCNN3,KLC1,IPO5,STXBP5,INSYN2,HECTD2,MBNL1,MEF2C,MEIS1,MMP16,ERICH3,ZNF680,SESN3,ADAM22,RSPO2,PABPC1L2A,NAP1L1,P2RY13,NASP,NCAM1,NDUFA5,NEFM,NFYA,CLEC9A,NRCAM,OCRL,OGDH,CLDN11,PAK3,CNTN3,PDE1A,PDE3A,ZNF655,PURG,C11orf49,RC3H2,ING3,EPB41L4B,SH3KBP1,PPP3CB,DIRAS2,PROX1,SIDT1,GON4L,CNTLN,PEX2,ZSCAN2,FAT4,ERI2,GTDC1,RFX2,RFX4,RGS12,SLC25A36,GSTCD,RORB,CCDC102B,RPL15,BAALC,LRRK2,CLIP1,ZNF568,CSRNP3,LRFN5,LINC00461,PEAR1,SH3GL3,FERMT1,KIF16B,CPEB3,NTNG1,FNDC3A,WDR37,PREX2,SEPHS1,RAB3GAP1,CCDC88A,SPHKAP,RCOR3,LIMCH1,SNAP25,SNCA,CMTR2,SNRPN,PALLD,UNC80,FAM219A,SOX1,KIF1B,CDK19,TSPYL2,C11orf87,ATP10B,CLSTN2,EPB41L3,NXT2,SEPT8,RGL1,DIP2A,FAM168A,TACR1,PJA1,CAMTA1,ADGRL3,AGTPBP1,TBX15,WDR7,SYNE1,OBSL1,PCDHB3,TEK,AP4E1,TGFBR3,HHIP,SLC44A1,HEY2,R3HDM1,TPM3,PDSS1,TTPA,CADM1,RPL7L1,SLAIN1,ZNF709,VSNL1,ZNF781,TCEAL7,FSTL5,EML6,PLPPR5,MFF,CADM2,PRDM2,STMN4,MDH1B,PCDH15,NAV3,C12orf4,RTN4,SLC39A12,NETO1,SLC4A10" MicroRNA hsa-miR-4306:mirSVR_highEffct hsa-miR-4306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.63E-104 1.48E-100 1.70E-103 1.57E-102 275 1174 "VWA5B2,KCNH8,CLK4,KDM5D,ARID1A,NDRG3,SLITRK1,ADD2,PTCHD1,ZNF578,PCDH10,ZNF687,LRFN1,USP28,PHF12,VAT1L,APP,MIER1,PLA2G4C,ATP1A3,CADM3,BACH1,ADGRB1,ADGRB2,CFLAR,THSD7A,KALRN,PTBP2,SLC25A14,VXN,LDB2,USP2,TMEM257,SYNGR3,DGKI,CDC42,LGI1,SRSF11,CASC2,LHX2,CPNE6,PPT2,COG1,CNGA3,TMEM155,PCYT1B,ARMC8,AKAP6,SUMF2,COL9A3,SLC4A8,ZFP28,SLC35F1,PREPL,GDA,ABCG1,OSBPL3,CSNK1G3,NCAN,PDE4DIP,UBXN2A,CTNND1,NRSN1,USP6NL,TCAF1,RIPOR2,DCAF8,TBC1D5,DGKB,PITPNC1,SPATA2,HP1BP3,KLHL3,ZC3H11A,SMG7,DMD,DNM1,DTNA,ABCC9,EBF1,SEZ6L2,FAM135B,FRY,GPR61,APH1A,EBI3,ING4,TMEM35A,EIF1,EPB41L1,DLC1,RACK1,ST3GAL6,FGR,POLK,EFCAB2,NPTN,STAU2,TBR1,ZNF512,GABRA3,AHCYL1,GALC,GAP43,DISC1,INPP5K,TUBGCP4,BRD8,GLS,TOX3,MSL3,STARD3,ZNF638,KDM2B,GOLGB1,PRUNE2,CCDC184,PCLO,GRIA2,GRIA4,PLCD4,SERP2,KAT7,GSTT2,SOX21,FAM222A,MAEL,RASSF8,UBE2QL1,PTGDR2,PACSIN2,VSIG4,ACOT7,HMGCL,HSP90AA1,ZNF678,INPP5B,LRRTM1,KCND1,KCNJ16,KCNN2,KCNN3,KLC1,CYP27C1,INSYN2,PIK3AP1,MAP2,MAP4,MAT2A,MDM4,MEIS1,SRSF12,MOG,MSI1,MSRA,MYO9A,RTL5,PABPC1L2A,NDUFA5,NINJ2,GLIPR1L2,PAK3,PBX1,PCDH9,CCSER2,PRIMPOL,RC3H2,SLC36A4,PPP2R5C,PRKACB,WDR25,PSMD13,CNTLN,PTPN13,PTPRE,QDPR,FAM66C,FAM184A,ZCWPW1,RDX,TRIM68,DPF2,PRRT2,MORC4,SLC25A36,RPRD1A,SETD5,KLHDC8A,CARF,LRRK2,ABCA11P,ATAT1,WLS,ZNF568,TRAPPC13,FAM192A,ATXN1,ATXN2,LRFN5,ASIC4,SH3BGR,MYO18A,BTBD3,SLC6A1,SLC8A1,CDK5RAP3,CPEB4,ZKSCAN3,SMARCC2,SORCS3,SNAP25,UNC80,KDM4B,SOX5,HECW1,SPTB,DDN,CLASP2,SMOC1,SSTR2,ZC4H2,INKA2,ELOVL4,PHLDB1,ZC3H4,ZFR2,FNDC9,SYN1,TMEM150C,ASTN2,EHBP1,TPCN2,TCF12,WDR7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,CDH22,GALNT17,MTMR14,TJP1,HEY2,TNR,NPL,TPM3,CHST5,ZNF384,ELP5,TSN,TSC1,SSBP2,TTC3,RPL7L1,BEST1,WIPF1,NPDC1,SF1,CELF4,LAMP5,SLC30A3,CA10,HPS4,NAV2,SLC17A7,PARP11,KAT6A,CAMK1G,KLHDC1,IFT88,NETO1" MicroRNA hsa-miR-103:mirSVR_highEffct hsa-miR-103:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.18E-104 2.35E-100 2.71E-103 2.49E-102 271 1143 "RALGAPA1,DGCR6,ABCF1,CLK4,NCKAP5,CSMD3,GALNT13,AXIN2,ERMN,AP2A2,KIAA1324,AK2,ALAD,SRPX,BBOX1,OGT,ANK1,ANK3,USP28,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,GPAM,ALS2,BCAS1,LGR5,CASK,SPTBN4,PLA2G4C,MARCH3,ASPH,ZBTB10,DDX3Y,ATP2A2,ZNF582,MPDZ,NRP2,CFLAR,SYNJ1,CACNA1E,CACNA2D1,THSD7A,KALRN,PTBP2,VSTM2A,RUNX1T1,AIFM1,CASC2,NDST3,CLCN3,COG1,C4orf33,QKI,SULT4A1,ARMC8,LETMD1,ABI3BP,ZFP28,HS3ST5,CLOCK,CREM,CSF1R,MICAL2,ATRNL1,VCAN,CTNND1,PPP6R2,GPRASP1,ARHGAP24,PHF19,ZFYVE16,LONRF1,GIT2,YTHDC1,JAKMIP2,C8orf34,CNIH3,DDX46,DRD1,RCAN1,DTNA,FAM78B,DYRK1A,EBF1,TSPAN5,FCF1,RBM12,YAF2,PHF20L1,MBNL2,EIF5,PLEKHA1,CEP85L,CORO2B,FCGR1A,ZNF589,KIAA1109,OLFM1,FGF12,CAP2,RGPD5,ATP13A4,NSG1,STAU2,PHYHIPL,GABRA1,GABRB1,GABRG2,CAB39,RAPGEF6,ARPP21,GALR1,DISC1,GFAP,PCDH17,PPARGC1A,GLRB,TOX3,TNRC6A,HTATSF1,OS9,INSM2,FERMT2,LNX1,ADGRA3,GPD2,GPR12,NR3C1,ATE1,GRM7,GSTM5,KAT7,WIF1,ZHX1,HTR2A,KNDC1,SLC35G1,KCNK1,KCNK2,KIF5A,KIF5C,TTYH2,STMN1,HECTD2,NCOA7,PIK3AP1,MAP4,AQP11,MBD1,MBNL1,MDM4,LRP1B,MEST,ZNF680,MYCN,NCAM1,NELL1,NF1,OTOGL,NOVA1,DNHD1,NTRK2,SNTG1,CNTN3,PCDH8,PRTG,PDE3B,CDK14,PLP1,SCHIP1,LRRN3,GDPD1,VPS13C,SIDT1,GDPD2,SNRK,TMEM260,PTPRD,PEX5,PPP2R3C,PID1,CEP97,FAT4,TRIM68,RET,ERI2,RFX4,TTLL7,MRPS18A,NUDT11,RNASEL,CARF,GSTCD,FBXW7,ATP8B4,LRRK2,SYNDIG1,KCNIP2,KCNIP1,CLIP1,SALL1,SEMA6D,SCN2A,SCN3A,SCN8A,SH3BGR,KIF21A,ITSN1,SH3GL2,PPM1E,CPEB3,NLGN1,ANKRD6,PAAF1,WDR37,ZNF365,FAM81A,RAB3GAP1,SLC20A2,SLC22A4,TET1,SMARCE1,ANKRD36,UNC80,ENKUR,NPAS3,CAMTA2,ACSBG1,PRRC2C,SYNE2,PLCB1,C12orf76,ATP11A,ADGRL3,TBCEL,SATB2,TRIM2,RPGRIP1L,WASHC4,FRYL,RNF216P1,TF,DICER1,ZFPM2,CRB1,TGFBR3,SLC44A1,TJP1,TK2,RIMBP2,CSMD1,RGMB,PRMT8,RUNDC3B,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE2H,AMOT,BCL2L13,P2RY12,ZNF711,EML6,LINC02210,ADAMTS9,WIPF2,MVB12B,PLSCR4,GOPC,ADAMTSL3,RNF170" MicroRNA hsa-miR-107:mirSVR_highEffct hsa-miR-107:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.18E-104 2.35E-100 2.71E-103 2.49E-102 271 1143 "RALGAPA1,DGCR6,ABCF1,CLK4,NCKAP5,CSMD3,GALNT13,AXIN2,ERMN,AP2A2,KIAA1324,AK2,ALAD,SRPX,BBOX1,OGT,ANK1,ANK3,USP28,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,GPAM,ALS2,BCAS1,LGR5,CASK,SPTBN4,PLA2G4C,MARCH3,ASPH,ZBTB10,DDX3Y,ATP2A2,ZNF582,MPDZ,NRP2,CFLAR,SYNJ1,CACNA1E,CACNA2D1,THSD7A,KALRN,PTBP2,VSTM2A,RUNX1T1,AIFM1,CASC2,NDST3,CLCN3,COG1,C4orf33,QKI,SULT4A1,ARMC8,LETMD1,ABI3BP,ZFP28,HS3ST5,CLOCK,CREM,CSF1R,MICAL2,ATRNL1,VCAN,CTNND1,PPP6R2,GPRASP1,ARHGAP24,PHF19,ZFYVE16,LONRF1,GIT2,YTHDC1,JAKMIP2,C8orf34,CNIH3,DDX46,DRD1,RCAN1,DTNA,FAM78B,DYRK1A,EBF1,TSPAN5,FCF1,RBM12,YAF2,PHF20L1,MBNL2,EIF5,PLEKHA1,CEP85L,CORO2B,FCGR1A,ZNF589,KIAA1109,OLFM1,FGF12,CAP2,RGPD5,ATP13A4,NSG1,STAU2,PHYHIPL,GABRA1,GABRB1,GABRG2,CAB39,RAPGEF6,ARPP21,GALR1,DISC1,GFAP,PCDH17,PPARGC1A,GLRB,TOX3,TNRC6A,HTATSF1,OS9,INSM2,FERMT2,LNX1,ADGRA3,GPD2,GPR12,NR3C1,ATE1,GRM7,GSTM5,KAT7,WIF1,ZHX1,HTR2A,KNDC1,SLC35G1,KCNK1,KCNK2,KIF5A,KIF5C,TTYH2,STMN1,HECTD2,NCOA7,PIK3AP1,MAP4,AQP11,MBD1,MBNL1,MDM4,LRP1B,MEST,ZNF680,MYCN,NCAM1,NELL1,NF1,OTOGL,NOVA1,DNHD1,NTRK2,SNTG1,CNTN3,PCDH8,PRTG,PDE3B,CDK14,PLP1,SCHIP1,LRRN3,GDPD1,VPS13C,SIDT1,GDPD2,SNRK,TMEM260,PTPRD,PEX5,PPP2R3C,PID1,CEP97,FAT4,TRIM68,RET,ERI2,RFX4,TTLL7,MRPS18A,NUDT11,RNASEL,CARF,GSTCD,FBXW7,ATP8B4,LRRK2,SYNDIG1,KCNIP2,KCNIP1,CLIP1,SALL1,SEMA6D,SCN2A,SCN3A,SCN8A,SH3BGR,KIF21A,ITSN1,SH3GL2,PPM1E,CPEB3,NLGN1,ANKRD6,PAAF1,WDR37,ZNF365,FAM81A,RAB3GAP1,SLC20A2,SLC22A4,TET1,SMARCE1,ANKRD36,UNC80,ENKUR,NPAS3,CAMTA2,ACSBG1,PRRC2C,SYNE2,PLCB1,C12orf76,ATP11A,ADGRL3,TBCEL,SATB2,TRIM2,RPGRIP1L,WASHC4,FRYL,RNF216P1,TF,DICER1,ZFPM2,CRB1,TGFBR3,SLC44A1,TJP1,TK2,RIMBP2,CSMD1,RGMB,PRMT8,RUNDC3B,ANKRD20A2,SSBP2,TTC3,RPL7L1,UBE2H,AMOT,BCL2L13,P2RY12,ZNF711,EML6,LINC02210,ADAMTS9,WIPF2,MVB12B,PLSCR4,GOPC,ADAMTSL3,RNF170" MicroRNA hsa-miR-132:mirSVR_highEffct hsa-miR-132:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.52E-104 2.54E-100 2.92E-103 2.69E-102 256 1022 "ACADM,NCKAP5,ARID1A,AXIN2,PWWP2A,KIAA1211,ESYT2,KIDINS220,CC2D2A,SEMA6A,PCDH10,SEMA7A,PHF12,APAF1,DDO,API5,SHTN1,MIER1,SEMA4G,TMEFF1,PDE8B,CAPRIN2,RNF182,DPY19L3,FUBP1,CACNA1B,CALB1,PTBP2,SLC25A14,HIP1R,CLDN10,CBFA2T2,DGKI,LRBA,CDC25B,LRRFIP1,LARGE1,CFL2,SRSF11,JAM2,RAB28,FBXO7,ARMC8,LETMD1,ZNF521,HAPLN1,SLC32A1,ABCG1,CSF1,CSNK1G3,DOCK4,ARHGAP32,RIPOR2,KIAA0586,ELMSAN1,ZEB2,ZBTB24,ALKBH8,RHOBTB1,SPOCK3,SV2A,DMD,USP3,GNE,E2F5,EDN3,EDNRA,CELSR3,PHF20L1,KMT5B,ASB3,EPB41,DENND4A,NCALD,EXTL2,CEP78,KAT8,PRKAG2,FOLR2,TRMO,TPK1,ARFGAP2,ATP6V1H,ZNF605,ST6GALNAC3,DKK3,GABRA2,ILDR2,RAPGEF6,ERAP1,INPP5K,MYOZ2,SULT1C4,AHDC1,NFU1,GHR,C1QL1,GK,MSL3,CBX1,INSM2,GPD2,GRIA2,SPACA9,ATE1,GRM3,GRM7,FAM19A2,PSIP1,HAS2,MIER3,SMAP1,EID2B,MSL1,SOWAHA,TJAP1,ZNF678,LRRTM3,NME9,KCNJ16,KCNK2,KTN1,LIMS1,PACRG,PIK3AP1,MBNL1,MEIS1,MEIS2,ADAM22,ZNF862,PABPC1L2A,HNRNPM,NDUFA5,NFE2L2,NOVA1,NRCAM,NTRK2,IGSF11,GPR88,PRTG,SLC10A4,CDK14,SERPINE2,CCSER2,PLP1,MAPKAP1,ING3,EPB41L4B,CRLS1,PPP2R5C,PPP2R5E,MAPK3,HYDIN,RELN,SNRK,MTMR10,PTPRD,PEX2,FAM184A,OXR1,RADX,KHDRBS2,GAL3ST4,GTDC1,RFX3,RFX4,ZFHX4,CCDC82,SETD5,EXD2,PRR5L,TCP11L1,CNTNAP3,LGR4,RTKN,KCNIP2,SALL1,CSRNP3,ATXN7,SCN2A,SCN3A,LRRTM4,SEC14L1,ARX,NTNG1,MAGI3,BCAN,SEC31A,FAM81A,EPN2,SLC6A1,SEPHS1,ARHGEF40,SLC12A2,MTERF2,RCOR3,RIMS1,SON,SOX5,FNBP1,MYCBP2,IDI2-AS1,CDK19,ZBTB43,C11orf87,POGZ,SS18,ERBIN,SEPT8,FGD4,PRRC2C,SYNE2,VPS13A,SYN2,MMS19,SEMA4A,DNMBP,CAMSAP2,ADGRL3,AGTPBP1,TMEM136,WDR7,DOCK9,RALYL,PCDHB6,PUM2,SIRT1,AP4E1,HHIP,SLC44A1,RBFOX2,TRIO,NEIL2,TSN,HIRA,SGK3,PLEKHH2,WIPF1,ETNPPL,ZBTB14,ZNF708,TRIM9,NDRG4,CELF4,CSDE1,TMEM178A,SCG2,PCDH15,RGS7BP,FAM13C,RTN4,CASC15,FXR1,FRMD6,IFT88,RNF146" MicroRNA hsa-miR-1308:mirSVR_lowEffct hsa-miR-1308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.56E-104 2.56E-100 2.95E-103 2.71E-102 279 1210 "SDE2,ASIC2,EMILIN3,ADCY6,GRAMD1B,ADORA2A,ADRA1D,KCTD16,RTL9,KIAA1324,HFM1,LRRC7,ALAD,CEP126,BCAR3,PCDH10,FAM135A,MRTFA,AMPD2,ANK2,SEMA7A,PKP4,KCNAB2,APOC2,MIER1,SLC7A14,KIAA1614,IGDCC4,ARNTL,CADPS,MARK4,CCAR2,STX16,RNF182,BACH1,LINC00847,CDK5R1,DST,SCAPER,MTMR3,JAZF1,KALRN,SPAG9,DGKI,LARGE1,UBE2L6,CHN2,CHRM1,CLTC,CNR1,IQCK,SLC4A8,ABI3BP,SLC35F1,SEC31B,CS,RGS6,IPCEF1,VAC14-AS1,CTH,DCAF4,CX3CR1,MYADM,ARHGAP32,TCAF1,ZNF337,DCC,YTHDC1,DNAJC6,JAKMIP2,PLEKHM1,MFAP3L,KIAA0319,SACS,WDR20,DLG4,DLX1,DMPK,CDON,DMTF1,ATN1,EDN1,FCF1,TMTC1,FSD1L,YAF2,EFNB3,MBNL2,AASS,CALCRL,DCTN4,EPB41,EPB41L2,RCAN2,LRRC23,VPS26C,CLVS1,EFEMP1,CHST15,ZMYND10,GORAB,HPCAL4,SEC23B,AGAP2,FLT1,ZBED3,UFM1,NSG2,STAG2,MEGF10,GAB1,ALDH1L1,CYP46A1,ADAM28,RNPS1,GRIA2,GRIN2C,GRM2,GSN,LINC01551,MAP4K5,GYG1,PADI2,MAN1B1,HNF4G,ZDHHC15,TCEAL6,SHISA6,SMAP1,SOWAHA,GAREM2,DOCK7,DIPK1A,LRRTM3,LRRTM1,ITPKB,KCNC1,KCNJ3,KCNJ10,KCNMA1,GATD1,KIT,GPR155,MAN2A2,MAP6,MBD1,MDFI,MEIS1,MMP16,ZNF680,MT3,TAGLN3,C10orf105,MYO9A,PABPC1L2A,NAP1L1,ZC3H12B,NEUROD1,NOVA1,DNHD1,LRIT2,DDR2,ZDHHC22,GLIPR1L2,SNTG1,DPY19L2P2,PDE3A,PDE3B,BEST3,CCSER2,NLE1,PCDH18,SPATA6,POLR2F,FSD1,CRLS1,PPP2R5C,RASGEF1B,PRKCZ,RELN,SLC22A23,APTX,TMEM260,ZSCAN32,PTPN13,ZSCAN2,NKAIN1,PID1,CEP97,TMEM255A,NWD1,RASGRF2,BSDC1,ZMAT4,GTDC1,SEC61A2,SLC25A36,RIC8B,TMLHE,PCMTD2,MRAP2,TMEM100,SNX22,SPIN3,TCP11L1,WLS,RTKN,YJEFN3,RYR3,DGLUCY,LRFN5,SCN2A,SCN2B,SCN4B,LRRTM4,SCNN1D,TNFRSF19,TRIM46,ZFP30,FBXO11,ST3GAL3,ZNF365,FAM214B,ATF7IP,SMARCA4,SMARCD3,IFT122,SNRPN,DOP1A,WDTC1,TRERF1,KIF21B,DOK5,ARHGAP26,STAU1,SEPT8,CEP68,ADHFE1,PHLDB1,KLHL7,SYT11,ZFR2,VAMP1,TACR1,KAZN,WWC1,SMG6,ANO4,PCDHB4,OBSL1,ENHO,MTMR14,TLR4,ERCC6L2,TMPO,FAM124A,TNFRSF1B,TPM2,ANO5,RFTN2,HEPACAM,EIF4ENIF1,DNAJC12,FLRT2,AGMO,DNALI1,LMAN2L,RNF103,HPS4,PCDH15,NAV2,FZD3,DOCK8,PHTF2,CERS6,RNF170,VANGL2,SNX14,SOCS4" MicroRNA hsa-miR-374b*:mirSVR_highEffct hsa-miR-374b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-104 3.71E-100 4.26E-103 3.92E-102 252 992 "ACADM,CLK4,CSMD3,BRAP,KCTD16,TAOK1,BCAR3,ARHGAP20,PCDH10,APC,CDK13,STK33,STX16,BACH1,MPDZ,KSR1,CDK5R1,SYNJ1,NAE1,JAZF1,CACNA1E,CACNB2,KALRN,PTBP2,VXN,CAST,CH25H,SPAG9,SEPT7,CDH10,LOC730101,MAGI1,CDO1,QKI,HECTD1,MAP4K4,NIPBL,TMEM155,RCHY1,COX4I1,TOGARAM2,MYRIP,CP,ANKRD44,CS,SEC24C,LRIG1,ARHGEF10,SOCS5,FAM169A,APPL1,RUBCN,HDAC9,TCAF1,KIAA0586,IST1,TMEM170A,PABPC5,PITPNC1,MYEF2,COPS7A,PLPPR4,CPEB2,DTNA,DYRK1A,DNM1L,GOLT1B,AASDH,EDNRB,YAF2,PHF20L1,OLIG2,ZIC4,ATP8A1,RACK1,FCGRT,ZSCAN30,FER,FGFR1,POLK,FLT1,COQ5,SMC2,UFM1,NPTN,KBTBD12,NRG3,MPP6,FYB1,GABRA2,GABRB3,CAB39,ILDR2,DENND2A,FAM120B,RAPGEF6,NEK6,GART,ALDH1L1,TUBGCP4,PCDH17,PPARGC1A,SPIN1,RAB30,MSL3,GNAL,GNAS,FERMT2,ADGRA3,GPD2,LPAR4,EML4,DIDO1,HPS5,ARHGAP36,AGBL5,ZDHHC15,MSL1,DOCK7,LRRCC1,PLD5,SCIN,SLC35G1,KCNN2,KIF2A,KIF5A,INSYN2,NCOA7,PACRG,MARK3,MATN2,MATN3,MBNL1,SYT9,MOV10,CCDC80,ADAM22,SCG3,CTNNA3,MTTP,NDP,SLCO1C1,NFE2L2,CHAMP1,OGG1,OPHN1,PAX6,PFKFB2,CDK14,NALCN,CCSER2,ZFYVE21,XRN1,PLIN1,PURG,LRP12,ING3,PPM1B,PPP2R5E,PPP3CA,RASGEF1B,PROX1,SNRK,MDGA2,CNTLN,TMEM260,PTPRD,PTPRE,FAM120C,TMEM255A,RAD17,RASGRF1,UBR7,PBRM1,RNASEL,RPRD1A,TMLHE,GSTCD,ROBO1,TMEM100,FBXW7,BAALC,ZC3H14,GLDN,ACER3,WLS,AP1AR,SALL1,SATB1,ATXN2,ELMOD1,PEAR1,ZFP30,KIF21A,KIF16B,NTNG1,SHC4,CHD9,ANKRD6,PAAF1,FAM81A,PREX2,CCDC88A,SLC12A2,SLC20A2,GKAP1,RIMS1,RBM34,SON,KDM3A,ZC3H13,DBNDD2,NPAS3,TAB2,POGZ,KANK1,SYNE2,VPS13A,CAMTA1,CAMSAP2,ADGRL3,ACSL6,WASHC4,PCDHB9,PUM2,ZFPM2,AP4E1,ERCC6L2,CHST5,RUNDC3B,STXBP4,RUSC1,FLRT2,VLDLR,VSNL1,WIPF1,WNT7A,TRIM9,CELF4,ZBTB38,FSTL5,SMARCAD1,EMSY,CADM2,SLC38A1,STMN4,STOX2,CAB39L,PAK5,TTC7A,PIANP,CPNE4" MicroRNA hsa-miR-122:mirSVR_lowEffct hsa-miR-122:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.88E-104 4.99E-100 5.72E-103 5.27E-102 285 1264 "VWA5B2,RALGAPA1,ABR,ASIC2,ASIC1,CSMD2,NDRG3,FMNL2,GALNT16,ADCY6,TMCC3,SORCS1,PTCHD1,HECW2,ANK2,FGD2,LCORL,APBA2,GPAM,PHYHD1,SLC7A14,MARCH3,CCDC74A,DACT3,CHRD,ATP1A2,STX16,LDHD,BSN,WASF1,DDR1,CACNB2,LURAP1,KALRN,CLDN10,TMEM257,LRRFIP1,EVI5L,CCPG1,CACNA2D2,SRSF11,CHGA,ARHGAP22,SLIT2,EPS15L1,RAB33A,NRXN3,FBXO7,QKI,SRP14-AS1,IGLON5,SUMF2,BAG4,SLC35F1,RGS6,CST3,PLXNA4,PHF19,LONRF1,DGKB,ZBTB24,ELMO1,SNAP91,SPOCK3,SRGAP3,G3BP2,ARNT2,DLG2,DLG3,GRIN3A,SLC12A6,ATN1,DSCAM,AASDH,EDN1,EDN3,CNNM1,TMTC1,EFNB3,EGFR,LPAR6,STARD3NL,EPB41L2,RCAN2,EPHB1,ANKRD13B,CD320,TBC1D16,EFEMP1,FKTN,ZSCAN30,ZNF589,OLFM1,IP6K2,PCYOX1,SEMA4D,FLT1,ANKFY1,EFCAB2,AK8,CAMKK2,ATP6V1H,STAU2,KBTBD12,NEURL4,HRASLS5,ARPP21,C15orf41,DNER,PCDH17,GGTA1P,GLS,PCDH11X,TMEM121B,CECR2,DIDO1,BTN2A1,GSTT2,ZBTB49,LINC01551,PSIP1,GUCY1A1,CELF3,BACH2,HLF,HMGB1,HPSE2,NEGR1,HSPA1L,IDH3B,NKD1,NME9,C2CD4C,KCNJ5,KCNJ10,KLC1,CYP27C1,KTN1,INSYN2,PAXBP1,MARK1,LYPLAL1,MEIS1,MID1,MITF,MOBP,GIT1,SAMD5,ADAM22,MTR,MYH7,MYT1,NASP,NCAM1,NELL2,DDR2,OLR1,OPCML,OPHN1,ZDHHC22,KCNK10,PDE1A,PDE1C,BEST3,OLA1,NLGN3,ST8SIA5,SCHIP1,ING3,SLC36A4,POLR2F,PPP2R5E,PRKCZ,MAPK4,MAPK9,RELN,UHRF1BP1,PTPRO,PTPRZ1,TUG1,PLEKHB2,OXR1,ZYG11B,RFX4,NUDT11,CCDC82,TMEM206,SYNDIG1,ATAT1,KCNIP1,DGLUCY,SATB1,HOGA1,SCP2,SOX6,GALNT10,TRA2B,FAM102A,PPM1E,FERMT1,NTNG1,SLA,SLC1A7,SMTN,WDR47,FAM214B,YPEL4,RAB3GAP1,ATF7IP,SLC22A4,COA1,MBD5,SNRPN,SCN3B,FAM219A,PDZD2,BDP1,SOX11,NMNAT2,ENKUR,HECW1,PEG10,ZC3H13,SPTB,KIF1B,SAMSN1,SEPT3,SYT11,FGD4,ZFR2,SYNE2,RHBDL3,C3orf70,KAZN,SEMA4A,KIAA1107,IQCE,SIN3B,AZIN2,SYNE1,AKNA,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ATP13A2,DICER1,DICER1-AS1,ZFPM2,SLC44A1,FBXL16,DDHD1,ERCC6L2,RIMBP2,TNFRSF1B,TPD52L2,C9orf85,ZNF346,TRH,ELP5,TRPS1,SLC35A4,LINC00689,PLEKHH2,P2RY12,ZBTB14,ZNF19,ZNF24,ATP6V0E2,ZNF142,REEP1,CA10,PMEPA1,SLC38A1,VPS35L,SIGLEC10,KCNAB1,DOCK8,MSRB3,ADAMTS10,FXR1,ST8SIA2" MicroRNA hsa-miR-520e:mirSVR_highEffct hsa-miR-520e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.05E-104 5.08E-100 5.82E-103 5.36E-102 293 1333 "KIAA1211,PTCHD1,MTUS1,GPR158,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,STK33,STX16,DPY19L3,BACH1,DCAF5,BID,CFLAR,ST3GAL5,MTMR3,JAZF1,SGCE,CA12,CALB2,CANX,AIFM1,ZBED1,MAGI1,CLGN,CFL2,CHN2,CASC2,TAOK2,IGFBP7-AS1,NRXN1,ABCG2,C4orf33,IQCK,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,GDA,SNCAIP,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,TOX,KIAA0586,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,ABCC9,GOLT1B,E2F5,EDN3,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DENND4A,DNAJC27,WAC,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,FYB1,ZMYND11,ARPP21,IGSF5,TUBGCP4,ADAM28,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,INSM2,POLL,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,HPS5,C1orf94,ARHGAP36,HSP90AA1,SMAP1,MSL1,C5orf24,JAK1,OLFM3,KCNMA1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NCF2,NELL2,NEUROD1,NF1,NRCAM,NUMA1,OCRL,OGG1,OPHN1,PCDH9,PCSK2,PDCD2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PLP1,PRIMPOL,TRHDE,PRRX1,SPATA6,EPB41L4B,DRAM2,PPP3CB,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,PTPRD,PTPRG,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,CCDC102B,TMEM100,MCMBP,LGR4,RPS20,TRAPPC13,AMER2,SCN2A,IL17RB,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,PPP4R3A,YPEL4,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ENKUR,ZC3H13,ZBTB43,LMO3,ATP10B,POGZ,LRRC4,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,CAMSAP2,UNC5D,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,TPD52L2,RGMB,PPIL6,ZNF709,VLDLR,VSNL1,PCDH20,LYPD6,LAMP5,SYNC,CADM2,PRTFDC1,RGMA,LINC02210,PRDM8,PRDM10,RNF103,SLC17A6,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-548l:PITA hsa-miR-548l:PITA_TOP PITA 1.00E-103 5.63E-100 6.44E-103 5.93E-102 206 657 "ADCY2,HECW2,ALCAM,FAM135A,CDC42BPA,EP400,APC,GAS7,USP37,PPP4R4,ARHGAP5,ASCL1,ZBTB10,DDX3Y,ATP2B1,SYNJ1,FUBP1,MTMR3,JAZF1,LDLRAD4,FOXK1,CACNB2,CALB1,PTBP2,MAP7,CFL2,SRSF11,FOXN3,SOCS6,CHN2,SYNPR,JAM2,LHX2,FAM19A5,QKI,CNR1,CNTN1,ARMC8,SLC4A7,AHCTF1,SLC35F1,CS,CSNK1G3,PHACTR3,APPL1,PLCXD3,PUM1,RIMS2,USP6NL,DOCK4,ARHGAP24,TOX,DNAJC6,ZEB2,MYEF2,SACS,G3BP2,DLG2,RAB39B,CPEB2,DTNA,E2F5,TMTC1,EGR3,ELAVL2,PAN3,ERBB4,F3,ATP8A1,FGF13,FOXF2,AFF2,NBEA,PDLIM5,FAM49B,STAG2,MEGF11,GABRB3,CAB39,ACSS1,CPLX2,ARFIP1,AHDC1,GK,TCERG1,TOX3,MSL3,PCDH11X,GPM6A,EML4,GRM7,FAM19A2,KLF12,BACH2,HLF,HMGCR,IGFBPL1,NEGR1,SOWAHA,C5orf24,JAK2,KCNA1,KCNK1,SFXN5,HECTD2,GPR155,CHIC1,LRP1B,MEIS1,KITLG,MKLN1,MXI1,MYCN,MYO5A,NEXMIF,PABPC1L2A,TCEAL5,NCAM1,NFIA,NFE2L2,NOVA1,NPTX1,NRCAM,TBC1D25,IGSF11,OCRL,CLDN11,GPR85,PIK3C2A,ANLN,XRN1,SMOX,PURG,MAPKAP1,STRN3,MAGEL2,POU3F2,MED1,PKN2,DIRAS2,WBP1L,SNRK,PTPN13,TMEM255A,ATG16L1,ARID4A,MSANTD2,RDX,REV3L,NUDT11,PBRM1,ZFHX4,LGR4,AP1AR,ATXN1,SCN2A,FAM19A1,FNIP1,HSPA4L,CHD9,CNKSR2,NLGN1,SEPHS1,SLC20A2,CPEB4,SMARCE1,RIMS1,SNAP25,PDZRN3,SP4,LHFPL4,KIF1B,SRPK2,CLASP2,SS18,ANKRD12,TCF7,RPGRIP1L,WASHC4,SIRT1,ZFPM2,ZFP91,HEY2,RIMBP2,TNS1,RBFOX2,RGMB,STXBP4,SLAIN1,FLRT2,BCL2L13,MEAF6,TRIM9,CELF4,REEP1,TMEM237,SLC30A4,EMSY,STOX2,KCNAB1,GOPC,FAM13C,PAK5,CERS6,FXR1,FRMD6" MicroRNA hsa-miR-450b-5p:PITA hsa-miR-450b-5p:PITA_TOP PITA 1.21E-103 6.78E-100 7.74E-103 7.13E-102 197 598 "XKR4,ELFN2,SLC12A5,USP31,SLC24A4,GPR158,PCDH19,OSBPL1A,TAOK1,SPOP,ANK3,CNTNAP1,TMEFF1,ARHGAP5,ZBTB10,DDX3Y,B3GALT2,DPY19L3,JAZF1,BSN,LDLRAD4,CALB1,CALM1,MAP7,TMEM257,CDH2,KCNAB3,CDH10,LGI1,CFL2,FOXN3,SOCS6,SYNPR,CLCN3,KIAA1549L,FAM189A2,FAM19A5,QKI,ARHGEF6,SLC4A7,MAGED1,MYRIP,ZNF521,TENM4,PHF14,CTNND1,RIMS2,ST18,FRMPD4,LONRF1,IST1,SIRPA,SPOCK3,SEC16A,DLG3,DMD,MED12,CPEB2,DYRK1A,GOLT1B,EBF1,FAM135B,KLHL5,KMT5B,ELAVL2,OLIG2,EPHB1,GPHN,SRRM1,ERBB2,ACSL4,MEX3B,FOXG1,AGAP2,AFF2,NBEA,GAB1,CAB39,PCDH17,GGT7,DHRS4,TNRC6A,GPM6A,EML4,TMEM121B,ADAMTS8,SOX21,ADAMTS6,MAP4K5,PADI2,KLF12,BACH2,MIER3,HMGB1,HNRNPK,CELF5,SMAP1,IGF1,C5orf24,KCNA1,KCNK2,STMN1,INSYN2,ARHGAP12,MAP2,MBNL1,MEF2C,KITLG,SAMD5,SESN3,RSPO2,NELL1,NFE2L2,OCRL,CNTN3,PCDH8,PCSK2,PDE4B,GPR85,PIK3C2A,PLCL1,FAT3,POLG,PPP2R5E,PPP3CA,PPP3CB,WBP1L,PTPRZ1,PTX3,TMEM255A,ARID4A,MSANTD2,FIGN,PBRM1,ROBO1,FBXW7,HUNK,KCNIP3,SALL1,CSRNP3,KIF21A,ITSN1,CPEB3,TRIM67,SPHKAP,CPEB4,GKAP1,RCOR3,SNCA,PALLD,PDZRN3,MYT1L,SOX2,SOX11,SP4,LARP4,NKAIN2,TTBK2,RHBDL3,SYPL1,ANKRD28,ANKRD12,CAMTA1,ADGRL3,DMXL2,SATB2,TRIM2,RPGRIP1L,DOCK9,ZFPM2,TJP1,KAT6B,ZNF384,PDSS1,TRPS1,TUB,SGK3,CADM1,VAV2,VLDLR,ZIC3,ZNF711,MICU3,ZBTB38,ZFAND5,PMEPA1,EMSY,MFF,EVI5,TMEM178A,NAV3,SLC17A6,RTN4,PAK5,SMIM8,HNRNPA3,CERS6" MicroRNA hsa-miR-22*:mirSVR_highEffct hsa-miR-22*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.24E-103 6.95E-100 7.94E-103 7.31E-102 295 1352 "ACLY,CLK4,NCKAP5,ADD3,GRAMD1B,KIDINS220,NLGN4X,INTS2,HECW2,CC2D2A,C1QTNF3,ARHGAP20,LRCH2,ANK2,LCORL,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ALS2,BCAS1,TNRC6C,AQP6,MIER1,ASCL1,EIF4G3,ATP1B3,ATP2B1,TTLL9,FUBP1,LINC00906,CALB1,THSD7A,SLC25A14,CAPN3,VSTM2A,CAST,BRSK2,MAP7,CBLN1,LRBA,ARHGEF2,CDC27,CDR1,TIGD7,CLTA,CLTC,NGEF,CNR1,CNTN1,SLC25A27,COL9A1,BTF3L4,LETMD1,CP,CLOCK,AKAP12,SNCAIP,RGS6,CSF2RA,CSNK1E,SOCS5,PDE4DIP,SLITRK5,ERC2,RIMS2,ECE2,TCAF1,CENPL,MATR3,PABPC5,JAKMIP2,MAGI2,BLOC1S6,RABGAP1L,DLG2,EXOG,DYNC1I1,NR1D2,DMTF1,DTNA,AASDH,SEMA3D,KLHL5,PHF20L1,EGFR,ELAVL4,MRNIP,PAN3,USPL1,EIF1,EPHB1,SRRM1,TLR7,EXTL2,CACNG2,FCGR1A,FCGRT,FDFT1,GORAB,POLK,SUCO,RGPD5,ATP13A4,FLT1,SGIP1,NELFCD,COQ5,EFCAB2,NBEA,PDLIM5,AP4B1,TVP23A,FYB1,PHYHIPL,DKK3,GABRA2,AHCYL1,GALC,ACSS1,KIAA1841,GATM,SULT1C4,AHDC1,PPARGC1A,GK,GLDC,GLS,ZNF638,RAB40B,GPD2,TDRKH,GPR34,NUDT21,PCLO,RAPGEF4,GRIA4,GRM5,BTN2A1,GSTT2,LINC01551,RABL2A,ATG4C,PADI2,NCKAP1L,LINC01102,HMGCL,HNMT,HNRNPK,ZDHHC15,ZIC5,RBPJ,LRRCC1,KCNB1,KCNK2,CREG2,MAOB,MDM4,LRP1B,MEIS1,DBNL,SAMD5,SLCO1C1,NOVA1,SLC11A2,NUCB2,TBC1D25,GPR88,OPA1,ZDHHC22,PAK3,PDE1A,PDE4B,GNG2,PFKFB2,NLGN3,TMEM38A,FAM216A,PRIMPOL,EXOSC10,SCHIP1,EPB41L4B,PRKAB2,RASGEF1B,RAB39A,PKN2,MAPK8,MASP1,ANKHD1,PLPPR1,PTK2,PTN,STK32A,EML5,C1orf109,CEP97,ACSS3,RAP1GDS1,VEPH1,GTDC1,RGS3,RGS7,RLBP1,SEC61A2,RIC8B,TMLHE,CARF,CCDC25,ADAL,RTKN,ATXN2,SCN3A,FAM19A1,SCN8A,SCP2,TNFRSF19,ELMOD1,TRIM46,ITSN1,FRMPD1,SHC4,FNDC3A,NLGN1,NUBPL,FAM81A,PREX2,WDR47,LRRC55,RAB3GAP1,CCDC88A,EFHD1,BTBD7,CDK5RAP2,MYH15,RCOR3,ANKRD36,RIMS1,SNCB,GLT8D1,HECW1,KDM4C,KIF1B,NPAS3,TAB2,SSTR2,LARP4,ERBIN,NXT2,MPRIP,KANK1,SULF2,PRRC2C,SYN2,SYP,SYT4,ATP11A,SEMA4A,CAMTA1,FAM208A,UNC5D,KLHL4,ANO4,TCEA1,KIAA0930,TCF7L2,ZEB1,USP32P1,RIMBP2,C5orf64,TP53BP2,TPD52L2,TPM1,NPL,ZNF346,TRIO,TRPS1,SGK3,FAM181B,VLDLR,BEST1,WRN,ZIC3,ZNF19,ZNF70,SLC26A10,CELF4,EML6,UPF3A,EVI5,PCDH15,KCNAB1,FIP1L1,UBE3B,PHTF2,NETO1,JPH3" MicroRNA hsa-miR-200c*:mirSVR_lowEffct hsa-miR-200c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.88E-103 1.06E-99 1.20E-102 1.11E-101 289 1302 "NCKAP5,CSMD2,CSMD3,ADAR,KLHL32,GALNT16,ADD3,PLEKHH1,NLGN4X,AP2A2,OSBPL8,LRRC7,SEMA6A,ALCAM,AMPH,ANK3,CDC14B,TMEM263,TMEFF1,ARNTL,STK33,NUMB,DDX3Y,ATP1B3,SLC2A11,ADAM23,BACH1,LINC00847,BBS2,MPDZ,HCN2,BMP7,DST,SYNJ1,ARHGEF7,CASTOR3,CACNA1G,CACNA1E,CACNB2,KALRN,PTBP2,CANX,VXN,CAST,METTL6,SYNGR3,DGKI,LRRFIP1,LOC730101,MAGI1,CCPG1,SRSF11,LSMEM2,QKI,MAP4K4,NIPBL,CNTN1,FAM149A,BTF3L4,COX4I1,AHCTF1,FAM171B,RBM39,GDA,CLIP3,CS,FEZ1,PUM1,EDRF1,DNAL1,TIAM2,RUSC2,GUCD1,FAM107B,CHRDL1,DLX1,DMD,USP3,CPEB2,ECM2,FARSB,EBF1,FAM135B,EDNRB,EIF5,ELAVL2,RGS17,TUBD1,STX2,SRRM1,EPS8,ZNF549,F3,ARMCX1,CLVS1,EFEMP1,ST3GAL6,PRMT5,TESK2,FER,GTF2IRD2,FGF12,FGF13,C1orf61,CAP2,C2orf88,EFCAB2,WDR83,APOPT1,FAM49B,NSG2,NSG1,ADGRA1,ZNF512,DKK3,GABRB1,GABRG1,GAD1,ARPP21,TMEM8B,KIAA1841,DNER,MSTN,COPS8,DBF4,GLI2,CBX1,GNAS,ADGRA3,GPM6A,GPR22,GRIA2,GRIA4,SPACA9,GRM7,GRM8,CIT,MFSD2A,GUCY1A1,GUCY1B1,IRAK3,KLF12,HMGB1,SCRG1,HNRNPK,HSD17B1,HSP90AA1,IDH3A,DOCK7,PLD5,USP54,IL6ST,ZNF385B,ITGAM,KCNA4,KCNK1,KCNMA1,LAMP2,LIFR,SYTL4,VWA5A,ARHGAP12,MEIS2,POC1B,AFF1,MOG,CCDC80,DDX25,LYRM9,ZC3H12B,RCOR2,NF1,ALDH1L2,NOVA1,NTRK2,IGSF11,OXTR,PCDH9,PCMT1,PCSK1,PCSK5,PDE2A,PDE4B,FAM98B,ANLN,FAM216A,JAKMIP1,HMGCLL1,STRN3,PRRX1,IRX1,PPM1B,PPP3CB,RASGEF1B,PRKCB,PRKCZ,PTN,TMEM260,PTX3,CEP97,ACSS3,FAT4,KHDRBS2,GTDC1,NUDT11,ZFHX4,GSTCD,CCDC102B,RPE,WLS,RTKN,KCNIP2,SEMA6D,ELMOD1,SGK1,ASAP3,FBXO11,SEC31A,SLC12A2,TMEM132D,LGI3,SLC22A4,ZKSCAN3,ZFP1,LMBRD1,FAM126B,SON,KIF21B,BEX1,TAB2,ATP10B,PBLD,SSTR2,NKAIN2,KANK1,SULF2,SYNE2,ADAMTS17,TAC1,DDHD2,CAMTA1,TAF9,UNC5D,EHBP1,TCF4,KIAA0930,TCF12,PHF24,RALYL,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,TEK,SLC44A1,THRA,DDHD1,ZFP91,TPM1,TPM3,ZNF384,ZNF346,TRPC1,RFTN2,CADM1,EIF4ENIF1,FLRT2,PLEKHH2,WRN,PCDH20,ZBTB14,MICU3,LYPD6,CELF4,REEP1,FSTL5,PRTFDC1,RNF103,HPS4,PCDH15,FIP1L1,FBXO36,JMJD1C,RNF170,NETO1" MicroRNA hsa-miR-223:mirSVR_highEffct hsa-miR-223:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.55E-103 1.43E-99 1.63E-102 1.50E-101 249 974 "CLK4,ARID1A,XKR4,DSCAML1,KLRC4,CCDC85A,AXIN2,PLEKHH1,GRAMD1B,DPY19L2P4,GPR158,AK2,ALCAM,OGT,DPP10,LRCH2,LCORL,USP28,PKP4,APC,API5,USP37,LGR5,LINC00173,MARCH3,CCDC74A,CAPRIN2,ASPH,ZBTB10,SLC4A4,ATP2B1,SLC2A11,SYNJ2,MTMR2,SGCE,IL33,CACNA1D,ZNF555,PTBP2,PRC1,CCKBR,USP6,AIFM1,SCARB1,CDC27,LRRFIP1,LGI1,MAGI1,TIGD7,FBXO7,FAM19A5,LY86,NIPBL,AKAP6,LETMD1,RCHY1,RTTN,ZFP28,FAM171B,HAPLN1,RGS6,CSF2RA,LRIG1,FEZ2,LRRC3B,CSNK1E,SOCS5,SLITRK5,GREB1,CTNND1,CCDC144A,TCAF1,TOX,PHF19,BRINP1,ARMCX2,SACS,SGSM2,RABGAP1L,CDON,DPH1,ABCC5,ABCC9,GOLT1B,RASGRP1,SEMA3D,YAF2,FAM13A,PHF20L1,EGFR,MBNL2,ABI2,TENM1,PLEKHA1,ETV1,F3,ARMCX1,CLVS1,FABP7,CACNG3,TUBA1B,FCGR1A,FCGR1B,OLFM1,CAMSAP1,FHL1,POLK,FOXG1,ANKFY1,SLC37A3,SORBS1,USP16,CSPG5,GABRA2,CAB39,BRPF3,KIAA1841,GHR,PPARGC1A,SPIN1,PCDH11X,GPR34,GRIA4,TMEM25,PSIP1,MAEL,C1orf94,ZHX1,ATXN2L,MIER3,SCRG1,HMGCL,CELF5,SMAP1,C5orf24,RBPJ,PLD5,LIX1,IL6ST,DIPK1A,INPP5B,METTL21A,KCNC1,KCNJ9,STXBP5,LAMA2,STMN1,LMO2,SYTL4,C2orf80,SMAD1,MAOB,MAP4,LRP1B,MEIS1,XRRA1,MSR1,CTNNA3,MX1,LAYN,NDP,NEFH,SLC11A2,NTRK2,OXTR,PAX6,PCMT1,GPR85,OLA1,ABCB1,PIK3C2A,A2ML1,HMGCLL1,PURG,SEPT4,PPP2R5C,PPP3CB,RANBP3L,PRKCB,PKN2,GRAMD1C,CNTLN,PTK2,PYGM,TMEM255A,GTDC1,YY1AP1,CCDC102B,FBXW7,ACER3,ABCA11P,RYR3,AP1AR,ATXN2,SCN3A,SOX6,ASRGL1,SCAF8,CNKSR2,ANKRD6,CLSTN1,ABLIM3,ZNF365,FAM81A,SLC8A1,SORCS3,CDK5RAP2,SNCA,KDM3A,TSPYL2,RAP1GAP2,POGZ,MESP1,EPB41L3,KANK1,NSFL1C,FGD4,SYT1,UNC5D,ANO4,DOCK9,SLC19A3,SLC35G2,C18orf54,TGFBR3,GZF1,ERCC6L2,HEY2,TMPO,RFTN2,ZKSCAN5,PLEKHH2,TBC1D15,P2RY12,CLDND1,PCDH20,LYPD6,REEP1,ANKS1B,SLC30A4,ZXDA,EMSY,PDSS2,FAM13C,KAT6A,NLRP3,NETO2,GAN,SENP7" MicroRNA hsa-miR-569:mirSVR_highEffct hsa-miR-569:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.33E-103 2.43E-99 2.77E-102 2.55E-101 250 984 "ACADM,CSMD3,ADD2,AP2A2,CC2D2A,TAOK1,ALAD,SPARCL1,SEMA6A,ARHGAP20,ZNF687,PARG,APAF1,LGR5,AQP4,STK33,CCAR2,RNF182,DPY19L3,BACH1,KSR1,DST,SYNJ1,FUBP1,JAZF1,CACNA1G,OSGIN2,MMD2,BTRC,CACNB2,CALM1,CANX,RUNX1T1,ZNF501,KRIT1,SCARB1,C1orf52,LRBA,CDC42,LGI1,L3MBTL4,CCPG1,RCBTB2,SRSF11,CASC2,RAB28,CLCN3,CLU,MAP4K4,CNGA3,CNTN1,AKAP5,SLC4A7,MFSD4A,CP,SLC35F1,CLIP3,FEZ2,SOCS5,PNPLA8,BOC,GAPVD1,ZFYVE16,LONRF1,YTHDC1,ZEB2,FBXL5,SNAP91,SGSM2,G3BP2,DLG2,RAB39B,DOCK2,ABCC9,E2F5,EDNRA,FCF1,SYT15,SH3GLB1,KMT5B,LPAR6,GOLGA7,KCTD3,EIF5,ELAVL2,PLEKHA1,ELAVL4,MRNIP,PAN3,DCTN4,EPHA5,ENPP6,CEP85L,TUBA1B,FER,SMC2,CELF1,AP4B1,STAG2,HRASLS5,CHL1,DISC1,GART,GCNT2,MSTN,ADAM28,PCDH17,MALT1,LYVE1,PRUNE2,FUT10,GRIA2,GRIA4,RABL2A,GUCY1B1,GYG1,ATXN2L,GABARAPL2,HSF2,SHISA6,USP54,SCIN,DIPK1A,LRRTM3,ITGAV,KCNA4,KCNK1,LIG4,SYTL4,HECTD2,FGFBP3,MAP4,LYPLAL1,MEIS2,MMP16,CTNNA3,NOVA1,SLC11A2,SETD4,GPR88,DPY19L2P2,ETFRF1,SLC10A4,NALCN,PIK3C2A,A2ML1,XRN1,HMGCLL1,PURG,SPATA6,SLC36A4,POLG,DRAM2,MINDY2,LRRN3,CRLS1,RAB39A,PKN2,GRAMD1C,PTN,PTPRB,OCIAD1,PTPRD,PTPRZ1,PPP2R3C,TMEM255A,PLEKHB2,ZNF793,OXR1,RADX,GTDC1,RFX3,UBR7,SEC61A2,RIC8B,GSTCD,ROBO1,TMEM206,RPL15,LGR4,CLIP1,FAM192A,SALL1,FNIP1,IL17RB,SH3GL3,MAGI3,FNDC3A,ANKRD6,ZNF365,KANSL3,SEPHS1,RAB3GAP1,SLC12A2,SLC15A2,BTBD7,SPHKAP,SMARCA4,SMARCE1,INAVA,LMBRD1,PDZD2,SOX5,TSPYL2,NPAS3,SRPK2,SSTR1,LARP4,VPS13A,PLCB1,TCF7L2,WASHC4,PCDHB3,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AP4E1,GZF1,TIAM1,TRIO,RUNDC3B,TTC3,SGK3,TBC1D15,XPO1,ZBTB14,AGMO,FMN2,ZNF189,SMARCAD1,ZNF225,WNK1,SLC30A4,MFF,VPS35L,SNX27,PDSS2,DNAH10,FAM13C,KAT6A,PHTF2,TIGD6,SLC39A12,NETO2" MicroRNA hsa-miR-15a*:mirSVR_lowEffct hsa-miR-15a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.41E-103 2.47E-99 2.81E-102 2.59E-101 297 1376 "RALGAPA1,EMILIN3,TKTL1,CSMD3,ADCY2,GRAMD1B,PWWP2A,LRFN2,KLHL13,KCTD16,KIAA1324,SMIM17,ARHGAP20,GOLGA7B,MRTFA,PI16,CCDC146,MAP4K3,PKP4,UPRT,ALS2,USP37,MIER1,PLA2G4C,DACT3,PCDHGB4,DDX3Y,SLC2A11,LINC00847,BCL2L2,DCAF5,CFLAR,SYNJ1,SYNJ2,ARHGEF7,IL33,CACNA1D,CAMK2G,CANX,VSTM2A,CAST,KRIT1,LRBA,LRRFIP1,MAGI1,IGFN1,MS4A7,EPS15L1,NRXN3,PPT2,CLCN3,CLTC,VAX2,CNTN1,ARMC8,ANKRD35,BTF3L4,AHCTF1,SMARCAL1,ZNF521,CHD1L,FAM171B,C2CD2,CREM,GDA,MROH8,ATRNL1,ERC2,EDRF1,NOS1AP,BOC,DCAF8,ZNF337,DGKG,ARMCX4,C8orf34,CEP170,CCDC3,DNM1,DNAH9,DPP6,KLHL5,SH3GLB1,EFNB3,EIF4G2,EMX2,RCAN2,SEZ6,ZNF549,MRVI1,F5,TUBB3,TOMM40L,FER,MED12L,GTF2IRD2,TMEM164,C2orf88,DACH2,STAU2,MSANTD4,SARAF,HRASLS5,GABRA3,ZMYND11,JPH4,RAPGEF6,ZNF274,SIGLEC8,SEPT9,IGSF5,KIRREL3,RUNDC3A,TXNL4A,TNRC6A,LUZP2,DCLK2,GRIA2,CIT,HLF,VSIG4,GABARAPL2,TLX1,ZDHHC15,OPALIN,HSF2,HTR5A,MSL1,IDH3A,IFI16,ZNF546,C5orf24,LRRC25,USP54,IL6ST,INPP5B,LRRTM3,ITPKB,SLC35G1,KCNJ3,KLC1,LAMP2,LIMS1,ARHGAP12,GPR155,MAP2,MAP4,MBD1,SYT9,CHIC1,LDLRAD3,MEIS1,DBNL,STK32C,BLOC1S2,MSR1,MT3,MXI1,NAP1L3,P2RY13,NF1,NFE2L2,NTRK2,ODF2,OGG1,GPR137C,ZDHHC22,PCDHGC3,PDE3B,PDE4D,GNG2,PFKFB4,NOMO2,PIK3R1,CCSER2,JAKMIP1,HMGCLL1,PMP2,SCHIP1,MED1,PPM1B,CRLS1,MAPK8,RELN,SAMD9,LAMA1,QRICH1,ZSCAN32,PTPRG,FAM120C,RAB5B,TMEM255A,ACSS3,RAD51D,ATG16L1,RASGRF1,ZDHHC14,GTDC1,RGR,ZFHX4,ARMC5,ROBO1,RORB,ELP2,RPL15,ACER3,STK32B,KCNIP1,CCDC112,FAM192A,RMI1,LINC00461,MRAS,ASAP3,CPEB3,SHC4,FNDC3A,ST3GAL3,ZNF365,BTBD3,PKNOX2,SLC6A11,SEPHS1,RAB3GAP1,SLC12A2,SLC22A4,NAXD,GKAP1,SMARCC2,SNCA,DOP1A,SPATA7,KIF1B,ZBTB43,SPART,NFASC,ZC4H2,RGL1,KANK1,PRRC2C,NUDT10,C3orf70,SYT4,ASTN2,UNC5D,FBXW11,ANO4,SIN3B,TCF7,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ZNF106,GZF1,TJP1,TMOD1,KCTD2,CSMD1,C5orf64,CDK20,TPM2,ZNF346,TRIO,UGT8,OSBP2,NSD2,ZNF24,TRIM9,ZBTB38,REEP1,PCBP1-AS1,ZFAND5,SYNC,PRDM2,SHD,CSDE1,ADAMTS9,VPS35L,GAL3ST3,PPP1R3F,KCNAB1,FIP1L1,FBXO36,SSPN,SOCS4" MicroRNA hsa-miR-96*:mirSVR_highEffct hsa-miR-96*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.00E-103 2.81E-99 3.19E-102 2.94E-101 276 1196 "SLC12A5,CDC7,ERMN,PTCHD1,KIDINS220,BEND6,WDR35,LRRC7,AMPH,LCORL,ANXA7,API5,APP,TMEM263,ARSE,LINC00173,ASPA,ASPH,ADAM23,BACH1,ADGRB3,SEC11C,KSR1,MTMR2,CA8,DDR1,PTBP2,VXN,CAST,CARS,LDB2,KRIT1,CERS5,AIFM1,DGKI,LARGE1,CDO1,SRSF11,CHGB,CASC2,B4GALT6,NDST3,TJP2,QKI,CNTN1,ARMC8,LETMD1,ABI3BP,TBPL1,ZNF521,CNRIP1,C2CD2,AKAP12,GDA,PDE4DIP,CST3,KIAA0040,CCDC144A,GPRASP1,LONRF1,KCTD8,DGKB,BRINP1,DNAJC6,ZEB2,HP1BP3,ZC3H11A,SPOCK3,NTM,AK5,DLX1,NR1D2,CPEB2,DTNA,DYRK1A,EDNRA,KLHL5,TMTC1,KMT5B,ELAVL2,C8orf37,RCAN2,EPHA5,KCNMB2,ENPP6,CEP85L,MRPL10,EZH1,ABCA8,FER,FLT1,TMEM107,SMC2,PDLIM5,ERGIC3,STAU2,DKK3,GAB1,GABRB1,GABRB3,GABRG2,IQGAP2,DISC1,WASF3,KIAA1841,SULT1C4,MSTN,ARFIP1,GK,COPS8,GLI2,GLYR1,GLRB,MSL3,KDM2B,PCSK1N,RAB40B,GOLGB1,GPR12,DIDO1,GRIA4,NR3C1,CLASRP,FAM19A2,RABL2A,MAP4K5,MIER3,ELOVL5,NEGR1,HSF2,HSP90AA1,SMAP1,DOCK7,IL12A,ITGAV,KCNN2,LMO2,C2orf80,MARK1,MARK3,MDM4,KITLG,AFDN,NRBP2,CTNNA3,NAP1L1,P2RY13,NELL1,SLCO1C1,NODAL,GPR88,PCDH9,PDCD2,PDGFRA,GNG2,BEST3,CDK14,FAM218A,PLCL1,TRHDE,EXOSC10,EPB41L4B,PACSIN1,PPM1B,PRKACB,GRAMD1C,MASP1,SAMD9,SIDT1,GON4L,BDNF-AS,SPDL1,PTN,OCIAD1,PTPRD,PTPRO,ARID4A,RBBP6,RBBP8,VEPH1,SLC6A15,RIT2,SLC25A36,PBRM1,CCDC82,RERGL,SETD5,KLHDC8A,CARF,ROBO1,RORB,FBXW7,PRR5L,STK32B,LRRK2,CNTNAP3,PTGR2,ABCA11P,WLS,SATB1,SCN3A,LRRTM4,LINC00461,ELMOD1,SUPT20H,TRA2B,NLGN4Y,CPEB3,SHC4,SLITRK3,NLGN1,ZNF365,PPP4R3A,EPN2,SPHKAP,COA1,LIMCH1,CMTR2,ANKFN1,ZNF415,SNRPN,WDTC1,KDM3A,KDM4C,KIF1B,CDK19,MCF2L2,RBM26,ITPRID2,THSD1,SSTR1,LARP4,LRRC4,NXT2,TTBK2,FAM168A,DNAJC9,PLCB1,SYPL1,TACR1,ANKRD12,TAF9,CAMSAP2,UNC5D,ACSL6,ZEB1,SYNE1,GPRIN3,FRYL,SIRT1,KHDC1,TGFBR3,HEY1,RIMBP2,RUNDC3B,SSBP2,CLHC1,TUBB1,FLRT2,USP1,CCDC14,XRCC4,ZIC1,MICU3,MKRN3,DNALI1,LRP8,STMN4,ADAMTS9,WNK3,PLSCR4,EPM2A,DNAH10,PHTF2,NETO1,SENP7" MicroRNA hsa-miR-29b:mirSVR_highEffct hsa-miR-29b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.81E-103 3.26E-99 3.70E-102 3.41E-101 279 1222 "KCNH8,RBM10,NCKAP5,KDM5D,XKR4,ADD3,CDC7,GRAMD1B,OSBPL1A,OSBPL6,TXNDC16,SMIM17,SPOP,ALK,AMPD3,DPP10,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PARG,APC,UPRT,GPAM,ALS2,BCAS1,SHTN1,TMEFF1,CDK13,MARCH3,CAPRIN2,ASPH,DACT3,BRINP2,STX16,ATP2A2,ATP2B1,N4BP2L1,RIPK1,ADGRB2,PROM1,DST,NAE1,WASF1,MMD2,PTBP2,CAMK2D,VSTM2A,RUNX1T1,C1orf52,DGKI,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A7,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,ANKRD44,GDA,CRYM,CS,LRIG1,ARHGEF10,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,DNAJC6,ZEB2,RHOBTB1,SV2A,EXOG,GRIN3A,DYNC1I1,DNM1L,WDPCP,EDNRB,FEM1B,SH3GLB1,PHF20L1,KMT5B,ABI2,SORBS3,ELN,TUBD1,ANKRD13B,RTN3,SCML2,EFEMP1,MED12L,MEX3B,RGPD5,DCTN2,TPK1,ATP2C1,ST6GALNAC3,NSG1,PNMA2,OGA,FYB1,STAG2,DKK3,GABRG2,ARPP21,DISC1,SESN1,GK,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,EML4,GPR37,PCLO,RAPGEF4,ADAMTS6,ZHX1,HRH3,VSIG4,HMGCR,HNF4G,HNRNPK,HTR2A,IGF1,IGSF1,SCIN,ZNF678,LRRTM3,KCNJ11,KIF5A,LAMA2,LIMS1,HECTD2,FGFBP3,MAP6,TM6SF1,MEIS1,MEST,MYCN,MYO9A,NEXMIF,NAP1L2,NAP1L3,NASP,NCAM1,OTOGL,NRCAM,OPHN1,PDGFRA,ENPP2,GNG2,CCSER2,PLP1,HMGCLL1,PURG,ANKRD16,PMP22,SDK2,ING3,EPB41L4B,POU3F2,PRKAB2,RASGEF1B,SLC26A11,GRAMD1C,MASP1,VPS13C,SNRK,PTHLH,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,CCDC82,ROBO1,PCMTD2,FBXW7,ATAT1,SALL1,LINC00461,SFPQ,TRA2B,SGK1,SH3BGR,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,WDR47,RAB3GAP1,SLC12A2,NAPB,ELMO2,BTBD7,TET1,ZKSCAN3,RIMS1,SNCA,MYO16,HECW1,UHRF1BP1L,KDM4C,SPTAN1,KIF1B,NPAS3,TAB2,NXT2,ZSCAN29,ELOVL4,ADHFE1,FGD4,PRRC2C,VPS13A,SYP,ANKRD12,TBCEL,TCF4,WDR7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TF,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,HEY2,R3HDM1,TPM1,NPL,TRPC3,FNDC5,KCNE5,TSN,TUBB2A,CLHC1,UGT8,VLDLR,BEST1,ZNF19,ZNF28,TRIM9,ZNF45,NDRG4,EML6,DPYSL5,PLPPR5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,NAV2,IFT88,NETO1" MicroRNA hsa-miR-518c*:mirSVR_highEffct hsa-miR-518c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.11E-103 5.12E-99 5.80E-102 5.34E-101 271 1157 "ACTN2,KDM5D,CSMD3,ADRB2,NLGN4X,PCDH19,LRRC7,ALCAM,BCAR3,SYT13,AMPD2,PHF12,PPFIA1,KCNAB2,UPRT,MARCH3,CAPRIN2,ASPH,TMEM108,STX16,ATP2A2,ATP2B1,TTLL9,BACH1,NRP2,KSR1,ST3GAL5,ARHGEF7,LINC00906,CASTOR3,GYG2,MMD2,BTRC,CA8,CACNB2,CACNB4,CBR1,CCNH,USP2,TMEM257,SOCS6,KMT2C,TPP1,SLC4A8,ZNF521,IGDCC3,HS3ST5,C2CD2,GDA,CLIP3,CS,SEC24C,ARHGEF10,PHF14,CTH,CFAP61,CTNND1,PUM1,EDRF1,TCAF1,PHF19,GIT2,ARMCX2,YTHDC1,ZEB2,DDX46,CHRDL1,DLG2,GRIN3A,OLIG1,DPH1,DNAJB6,ABCC5,EDN1,EDNRB,HIPK3,CNNM1,OPTN,YAF2,PHF20L1,KMT5B,PLEKHA1,TNK2,RGS17,PAN3,EPHA5,EPHB1,STX2,EFS,MRPL37,FCGR1A,TOMM40L,STRADA,GORAB,MED12L,KIAA1109,FOXM1,ANKFY1,NELFCD,JKAMP,DKK3,GAD1,AHCYL1,ZMYND11,JPH4,DISC1,MSTN,GHR,TCERG1,COPS8,PCDH11X,PSRC1,CNDP1,GPR12,LINC01551,GYG1,WIF1,ARHGAP36,AGBL5,NEGR1,CELF5,SMAP1,IDH3A,SOWAHA,DOCK7,SCIN,INPP5B,ZNF385B,LRRTM3,NME9,KCNK1,PIK3AP1,MAN2A2,MBD1,SYT9,SRSF12,MEST,MMP16,MOBP,CCDC80,MYCN,NF1,DNHD1,SLC11A2,CLDN11,PAK3,PCDH9,PDE3A,PDGFRA,SERPINI1,ST8SIA5,SMIM7,PURG,PRIMPOL,ING3,SEPT4,SH3KBP1,POU3F2,RANBP3L,PKIA,PRKCG,PKN2,HYDIN,SNRK,WDR25,SPDL1,C1orf109,ZNF615,RALGDS,RASGRF2,BSDC1,RDX,ZYG11B,DPF2,GTDC1,FIGN,RGS7,RGS12,SETD5,ELP2,PCMTD2,RPE65,BAALC,SPIN3,ATP8B4,ATAT1,KCNIP2,ZNF568,TMEM156,CSRNP3,FAM19A1,MRAS,SH3BGR,FERMT1,MAGI3,NUBPL,DHX30,FAM214B,SLC6A1,CXXC4,LIMCH1,RIMS1,LMBRD1,SNRPN,KIF21B,BDP1,ZSWIM8,KDM4C,TEX2,RBM26,NPAS3,POGZ,COLGALT2,EPB41L3,SS18,ERBIN,STAU1,CEP68,JMJD6,PLCB1,TAF9,TBCEL,TBX15,EHBP1,ZEB1,RPGRIP1L,TCF12,SYNE1,NAT16,FRYL,CHST8,CRB1,ITGB3BP,GPR161,SLC44A1,FBXL16,TK2,DDHD1,KCTD2,SEZ6L,NPL,TPM2,PRMT8,ELP5,RUNDC3B,TRPC3,ZMYND8,AMOT,UGT8,FLRT1,PLEKHH2,WIPF1,RICTOR,ETNPPL,CFAP298,SF1,TRIM9,ZNF195,SLC30A4,CADM2,PRDM2,CSDE1,PPP1R3F,PLSCR4,CASC15,CAMK1G,CERS6,ZNF248,DPF3,CBLN2,SLC4A10" MicroRNA hsa-miR-144:PITA hsa-miR-144:PITA_TOP PITA 1.39E-102 7.81E-99 8.84E-102 8.14E-101 195 592 "ARID1A,CCDC85A,AXIN2,USP31,GPR158,PCDH19,TAOK1,SEMA6A,ALCAM,ALS2,CACHD1,CDC14B,ARHGAP5,CADPS,ASCL1,MARCH3,ZSCAN18,ATP2B1,ATP2B2,NOL4,NRP2,JAZF1,LDLRAD4,CACNB2,CALB1,CANX,USP6,TMEM257,CDH2,CFL2,SOCS6,CHN2,B4GALT6,LHX2,KIAA1549L,QKI,CNN3,CNR1,ACBD5,PPP1R16B,PUM1,ST18,USP6NL,DOCK4,GAPVD1,TOX,ZEB2,MYEF2,CEP170,ALKBH8,RHOBTB1,SNAP91,SRGAP3,DMD,CPEB2,ABI1,DYRK1A,RBM12,SH3GLB1,MBNL2,ABI2,GOLGA7,EIF4G2,ELAVL2,RGS17,CALCRL,EPB41,EPB41L1,KCNMB2,SRRM1,ACSL4,ZIC4,EFEMP1,ST3GAL6,MED12L,FOXG1,DCTN2,CAMKK2,KHDRBS3,ST6GALNAC3,BRPF3,AHDC1,GFRA2,PPARGC1A,GLDC,TNRC6A,LUZP2,LPAR4,RAPGEF4,NR3C1,KIF3A,WIF1,ZHX1,BACH2,MIER3,HSF2,ZIC5,USP54,SLC6A17,JAK2,KCNA4,KCND2,INSYN2,LIFR,NCOA7,SMAD1,MBNL1,MEIS1,MEIS2,KITLG,MITF,MSI1,MYO5A,NEXMIF,MYT1,ZC3H12B,NF1,NFE2L2,NPTX1,CNTN3,PDE3B,PDE4D,PIK3C2A,PCDH18,HMGCLL1,LRP12,PRRX1,PPARA,PRKACB,PKIA,SYTL2,CNTLN,OXR1,ZFHX4,ZNF532,SETD5,LGR4,SALL1,SEMA6D,ATXN1,SCN2A,SCP2,SMPD3,CPEB3,FNDC3A,CLSTN1,SEPHS1,CCDC88A,SLC12A2,SORCS3,SNCA,FAM126B,SOX1,MYT1L,SP4,ARHGAP26,CDK19,CAMTA2,SS18,ST5,STAU1,RGL1,SYT11,ZC3H4,ADAMTS17,ANKRD28,ATP11A,CAMSAP2,FAM208A,FBXW11,TRIM2,RPGRIP1L,WASHC4,RALYL,PCDHB7,TEK,DICER1,TJP1,SGK3,PCDH20,FMN2,ZBTB38,MFF,CADM2,SLC38A1,RGMA,NAV3,TMEM163,WNK3,PAK5,KAT6A,PHTF2,NETO2,SLC4A10,SENP7" MicroRNA hsa-miR-520d-3p:mirSVR_highEffct hsa-miR-520d-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.35E-102 1.32E-98 1.49E-101 1.37E-100 295 1367 "ACADM,KIAA1211,PTCHD1,ADRB2,MTUS1,GPR158,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,SUGT1P4-STRA6LP-CCDC180,API5,APP,STK33,ASPH,STX16,DPY19L3,ATP6V1G2,BACH1,DCAF5,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,CA12,CACNA1E,CALB2,THSD7A,SYT6,VSTM2A,AIFM1,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,IQCK,BTF3L4,AKAP5,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,TOX,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,GRIN3A,HS3ST4,HS3ST2,DMTF1,DRD1,DTNA,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DENND4A,DNAJC27,CORO2B,MED12L,POLK,SUCO,SGIP1,TACC2,USP16,MSANTD4,FYB1,MEGF11,HRASLS5,ZMYND11,ARPP21,IGSF5,GGTA1P,COPS8,HPGDS,GLDC,TNRC6A,GLUL,ZNF638,MAP7D2,INSM2,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,KAT7,HPS5,C1orf94,ARHGAP36,HSP90AA1,SMAP1,MSL1,IDH3B,ITGAV,JAK1,OLFM3,KCNJ16,KCNMA1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,SRSF12,KITLG,PPM1L,POC1B,MRPL42,ADAM22,MYCN,LAYN,MYO9A,NACA,NELL2,NEUROD1,NF1,NRCAM,NUMA1,OCRL,OGG1,OPA1,OPHN1,PCDH9,PDCD2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,PRRX1,SPATA6,DRAM2,MED1,PPP3CB,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,PTPRD,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,LRRC4,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,CAMSAP2,UNC5D,ADGRL3,TBCEL,CUX2,TCF7L2,ZEB1,SZT2,RALYL,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,AKTIP,TIAM1,NR2E1,TNFRSF1B,TNS1,RGMB,PRMT8,TRPC1,PPIL6,PITPNB,FAM181B,VLDLR,VSNL1,FMN2,LYPD6,LAMP5,PLPPR5,SYNC,WNK1,CADM2,RGMA,LINC02210,PRDM8,PRDM10,SLC17A6,NELFE,PLSCR4,FAM13C,DOCK8,MARCH8,PAK5,FAM219B,NLRP3,SNX14,IFT88,DPF3" MicroRNA hsa-miR-520b:mirSVR_highEffct hsa-miR-520b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.37E-102 1.33E-98 1.50E-101 1.38E-100 291 1332 "KIAA1211,PTCHD1,MTUS1,GPR158,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,STX16,DPY19L3,DOCK11,BACH1,DCAF5,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,SGCE,CA12,CALB2,CANX,AIFM1,ZBED1,LGI1,MAGI1,CLGN,CFL2,CHN2,CASC2,TAOK2,ABCG2,C4orf33,AKAP7,AKAP5,TCEAL2,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,HAPLN1,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,DCAF8,TOX,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,HS3ST4,OLIG1,HS3ST2,DMTF1,DRD1,ABCC9,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,FAM13A,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,FYB1,MEGF11,CAB39,ZMYND11,ARPP21,IGSF5,TUBGCP4,ADAM28,GGTA1P,GHR,COPS8,GLDC,TNRC6A,GLUL,ZNF638,MAP7D2,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,FICD,HPS5,C1orf94,ARHGAP36,HSP90AA1,SMAP1,MSL1,C5orf24,IGSF1,JAK1,OLFM3,KCNMA1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NUMA1,OCRL,OGG1,OPHN1,PCDH9,PCSK2,PDCD2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PLP1,PRIMPOL,TRHDE,MAPKAP1,PRRX1,SPATA6,DRAM2,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,PTPRD,RAB5B,CEP97,ACSS3,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,TRIM68,GTDC1,FIGN,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,PCMTD2,CCDC102B,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ENKUR,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,KLHL7,FGD4,SYNE2,DNAJC9,PLCB1,CAMTA1,TAF9,CAMSAP2,UNC5D,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,HHIP,AKTIP,GZF1,TIAM1,NR2E1,TNS1,TPD52L2,RGMB,TRPC1,PPIL6,PITPNB,PLEKHH2,VLDLR,PCDH20,LYPD6,LAMP5,SYNC,CADM2,RGMA,CSDE1,LINC02210,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,PAK5,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-92a:mirSVR_highEffct hsa-miR-92a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.43E-102 1.37E-98 1.54E-101 1.42E-100 241 921 "SYN3,NCKAP5,CSMD2,CSMD3,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,MIER1,ASPH,DDX3Y,ATP2A2,MTMR9,B3GALT2,NOL4,ADAM23,ADGRB3,MPDZ,HCN2,CDK5R1,SYNJ1,CACNA1I,OSGIN2,CA8,KALRN,CAMK2A,VSTM2A,MTMR7,AIFM1,CDC27,CDH10,SOCS6,CHM,NDST3,NRXN3,HECTD1,NIPBL,TMEM155,CNRIP1,HS3ST5,FAM171B,CRHBP,SLC32A1,ATRNL1,VCAN,SOCS5,FAM169A,SLITRK5,ERC2,APPL1,ST18,EDRF1,CCDC144A,DOCK4,HDAC9,DAPK1,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,SACS,G3BP2,DLG2,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,YAF2,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,KCNMB2,TMEM74,KIAA1109,FHL1,POLK,ATP13A4,SLC37A3,TACC2,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,IQGAP2,GAP43,GHR,SPIN1,GLYR1,PCDH11X,CNDP1,GPD2,GPM6A,LPAR4,TPPP,GRIA1,DIDO1,RFFL,GRM1,GRM7,HAS2,MIER3,SCRG1,HNMT,MSL1,RBPJ,USP54,SLC6A17,ITGAV,C2CD4C,KCNK1,KLC1,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,GPR137C,PDE1A,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,TRHDE,STRN3,ING3,CEP41,PTPRD,PTPRO,PEX5,TMEM255A,PLEKHB2,RAD51D,ARID4A,BSDC1,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPE65,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,SCN3A,FAM19A1,FNIP1,SUPT20H,TRA2B,CPEB3,MYO18A,CHD9,CNKSR2,ZNF430,RAB3GAP1,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PALLD,UNC80,PDZD2,MYCBP2,TEX2,KIF1B,NPAS3,PBLD,ITPRID2,ELOVL4,RGL1,FGD4,ZFR2,SYN2,SYPL1,SYT1,SYT4,CAMTA1,ANO4,SATB2,SYNE1,DOCK9,SIK3,HHIP,KCTD2,TPM4,SYNPO2,TRIO,SGK3,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,FMN2,MFF,LRP8,EVI5,RNF103,NAV3,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,SLC4A10" MicroRNA hsa-miR-576-3p:mirSVR_highEffct hsa-miR-576-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-102 1.60E-98 1.80E-101 1.66E-100 248 976 "ASIC2,NCKAP5,KLHL32,SLITRK1,GALNT13,ADD3,AXIN2,CDC7,ERMN,INTS2,WDR35,SMIM17,AMPH,ZFAT,LCORL,GPAM,ALS2,CACHD1,BCAS1,CDK13,CAPRIN2,DACT3,ATP2A2,ATP2B2,NOL4,DPY19L3,ATP6V1G2,ATP6V0A1,TTLL9,ADGRB3,BCHE,SYNJ1,SYNJ2,OSGIN2,KALRN,SLC25A14,BRSK2,MTMR7,INA,LRBA,LRRFIP1,LGI1,LOC730101,CCPG1,SRSF11,PLEKHB1,KMT2C,COG1,TPP1,TMEM155,FHL5,CNR1,LETMD1,MYRIP,GDA,TRIM69,NCAN,ERC2,GREB1,RIMS2,RUBCN,TCAF1,ZFYVE16,LONRF1,MYEF2,SV2B,DLG2,GRIN3A,DMD,DNAH9,DPYSL2,GOLT1B,KLHL5,YAF2,EGFR,EGR3,ELAVL2,PLEKHA1,EML1,RCAN2,CLVS1,DLC1,ZNF589,FGF12,PRKAG2,CAP2,EFCAB2,MSANTD4,STAG2,CAB39,GAD2,ARPP21,MTHFD2,ZNF559,DISC1,ATP8A2,SULT1C4,PPARGC1A,BRD8,TOX3,ZNF638,TDRKH,STON1,GRIA2,DIDO1,GRM5,PSIP1,ELOVL5,C9orf129,ZDHHC15,ZNF546,ZIC5,USP54,IL6ST,NME9,OLFM3,KCNK2,KCNMA1,KLRC2,HECTD2,FGFBP3,LSS,MBNL1,SYT9,MID1,POC1B,MOG,MOV10,ERICH3,ZNF680,CPNE9,MSI1,ADAM22,NRBP2,CTNNA3,DNHD1,LRIT2,NPPA,OPA1,P2RY1,GPR137C,PBX1,PCSK1,PDGFRA,BEST3,NALCN,PLCL1,PCDH18,PDZRN4,PMP22,STRN3,LRP12,ING3,EPB41L4B,NXPH1,TATDN3,PPP2R5E,MAPK9,GRAMD1C,SPDL1,PTPRZ1,QDPR,ATG16L1,ZCWPW1,MSANTD2,SLC6A15,REV3L,RFX4,ZDHHC4,ATP8B4,LGR4,SOX8,RTKN,ZNF331,FNIP1,SUPT20H,SGK1,ITSN1,SHC4,CHD9,FNDC3A,RPH3A,BTBD3,DHX30,SMTN,ZNF430,RAB3GAP1,CCDC88A,SLC15A2,ANKRD36,DOP1A,PDZD2,MYT1L,IDI2-AS1,DBNDD2,TAB2,ATP10B,CLASP2,STOX1,C3orf70,PLCB1,SYPL1,ANKRD28,TAL1,FAM208A,ADGRL3,SIN3B,TRIM2,WASHC4,SYNE1,DOCK9,OBSL1,DDHD1,ERCC6L2,TMOD1,BEX4,CSMD1,SYNPO2,PRMT8,SMUG1,ELP5,TRPC3,ANO5,TMEFF2,XRCC4,ZIC3,ZNF24,REEP1,WNK1,LRP8,ADAMTS9,TMEM178A,HPS4,WNK3,NELFE,RGS7BP,RTN4,UBE3B,PAK5,KAT6A,FBXO36,CASC15,ADAMTSL3,JMJD1C,RNF170,FRMD6,SENP7,JPH3" MicroRNA hsa-miR-556-3p:mirSVR_highEffct hsa-miR-556-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.92E-102 1.64E-98 1.84E-101 1.70E-100 261 1080 "SYS1,TKTL1,GPRIN1,CSMD3,FMNL2,ADARB2,CCDC85A,SORCS1,ADRB2,KIDINS220,AP2A2,MTUS1,AMT,OGT,DPP10,USP28,ALS2,MIER1,ASCL1,SLC4A4,STX16,MTMR9,NOL4,ADGRB3,KSR1,DST,NAE1,DDR1,CACNB2,TMEM257,LOC730101,RCBTB2,CHM,CHN2,CASC2,NDST3,KMT2C,CLTA,IQCK,BTF3L4,ABI3BP,TCEAL2,MFSD4A,CP,CREM,CRHBP,HINFP,SLC32A1,ANKRD44,ARHGEF10,CSNK1G3,SIPA1L1,PLXNA4,UBXN2A,RIMS2,USP6NL,CCDC144A,DOCK4,HDAC4,ZFYVE16,MATR3,DGKB,SIRPA,DNAL1,SV2B,G3BP2,FAM107B,ZNF582-AS1,CHRDL1,PDCD6IP,DNAJB6,ABCC9,EDN1,ANKRD46,KLHL5,PHF20L1,MBNL2,KCTD3,DCTN4,TUBD1,EPHA5,EPS8,KATNAL1,GMPR2,F3,ACSL4,FCGR1B,CEP78,FCGR3A,ZSCAN30,GORAB,KIAA1109,FGF1,POLR1B,FGFR3,POLK,SUCO,VTI1B,FAM49B,NPTN,ERGIC3,NSG2,FYB1,STAG2,TRAF3IP2,BRPF3,ZMYND11,DISC1,IGSF5,ALDH1L1,SULT1C4,PPARGC1A,TCERG1,GLS,TNRC6A,PCDH11X,ZNF638,FUT10,EML4,ATP2B1-AS1,GRIA2,GRIA4,GRIK2,FAM19A2,COQ10A,AP4S1,GUCY1B1,ZHX1,NXPH2,HLF,HNF4G,HTR5A,IDH3A,ZNF546,IGSF1,SLC35G1,KCNH1,KCNK2,KLRC2,STXBP5,STMN1,MBD1,MEF2C,MEIS2,SRSF12,NDUFA5,NEK1,SLCO1C1,NFE2L2,P2RY1,PAH,PBX1,DPY19L2P2,PCDH9,PCSK2,PDGFRA,SERPINI1,NALCN,PIK3C2A,FAM218A,GPSM2,PLCL1,PLP1,HMGCLL1,C11orf49,PACSIN1,FAT3,NXPH1,MED1,PPM1B,PPP2R5C,PKIA,MAPK9,PTHLH,STK32A,C1orf109,PID1,ZNF793,ZCWPW1,ZNF493,RBBP6,RGS3,ZFHX4,RAVER2,CARF,PCMTD2,RPE,ZC3H14,WLS,ZNF568,RYR3,NCBP3,AP1AR,SAFB,SEMA6D,SATB1,SCN2A,SCN3A,TNFRSF19,SEC14L1,SCAF8,CPEB3,FHOD3,BTBD3,KANSL3,BTBD7,SLCO1A2,ANKRD36,MBD5,SNRPN,PDZD2,TRERF1,ENKUR,HECW1,SPTB,KIF1B,RBM26,NXT2,STAU1,NEK4,VPS13A,FNDC9,TMEM150C,SYT1,DDHD2,MLST8,ADGRL3,FBXW11,TCEA1,EHBP1,TCF7L2,ZEB1,PCDHB4,TEK,AP4E1,SLC44A1,TNR,SYNPO2,METTL3,KCNE5,TTC3,SGK3,BCL2L13,CLDND1,GUSBP1,LGI4,ZNF708,ZFAND5,WNK1,CADM2,PRTFDC1,LRP8,PRDM8,ADAMTS9,PDSS2,EPM2A,RGS7BP,HNRNPA3,NUP214,ZNF248,NETO1" MicroRNA hsa-miR-192*:mirSVR_lowEffct hsa-miR-192*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.06E-102 1.72E-98 1.93E-101 1.78E-100 297 1386 "KCNH8,ASIC2,ACTN2,CSMD3,GALNT16,ADCY2,SLC12A5,SORCS1,ERMN,ADORA3,RNF150,BEND6,INTS2,TXNDC16,LRRC7,ALCAM,CEP126,CARNS1,UNC79,AMPH,ZFAT,OGT,DPP10,MAP4K3,PPFIA1,CACHD1,MIER1,ARHGAP5,LINC00173,CCDC74A,DDX3Y,ATP2A2,RNF182,BACH1,BCL2L2,CFLAR,KSR1,MTMR3,CACNA1E,TRIM41,VSTM2A,CBLN1,DGKI,REPS2,LRRFIP1,DLGAP1,CFL2,SRSF11,SOCS6,CHN1,KMT2C,CLTC,QKI,SRP14-AS1,HECTD1,MAP4K4,SLC4A7,SLC4A8,SMARCAL1,TOGARAM2,PREPL,HAPLN1,GDA,SNCAIP,CSF2RA,IPCEF1,SIPA1L1,CST3,UBXN2A,CTNND1,CCDC144A,BOC,GPRASP1,IST1,DGKB,SCRN1,DNAL1,ARMCX4,DCC,HP1BP3,CEP170,TMEM130,RHOBTB1,SV2A,DLG2,DMTF1,SLC12A6,PDCD6IP,DNM1L,ABCC9,WDPCP,SYT15,FSD1L,EIF5,IRAK4,EMX2,EPB41,ENPP6,SRRM1,NCALD,CDHR1,TMEM74,DUSP27,NRN1,F5,TAOK3,ATP8A1,RACK1,TOMM40L,FGF13,SEC23B,SEMA4D,NOP56,WDR83,PNMA2,SARAF,ZNF512,B4GALNT1,ZNF234,INPP5K,GHR,GLS,ADGRA3,CNDP1,MCHR1,RAPGEF4,GRIA2,PLCD4,GRIK2,GRM5,GRM8,FAM19A2,RNFT2,ADAMTS6,MAP4K5,WIF1,IRAK3,C1orf94,FRMD3,C2orf72,IL6ST,ITGAV,ITPKB,SLC35G1,KCNA4,KCNJ10,KCNK1,KCNK3,KCNMA1,KCNN2,KIF5A,KIF5C,KLRC3,IPO5,HECTD2,GPR155,MARK1,MBNL1,MIA2,CCDC80,CTNNA3,HS6ST3,MYO9A,BEX5,NOS1,CNOT4,NOVA1,NTRK3,OPRL1,OXTR,PCSK2,CDK18,PDE3B,PDGFRA,A2ML1,PLCL1,PURG,MAPKAP1,STRN3,SCHIP1,MAGEL2,FSD1,PTPA,PRKACB,CEP41,LRRC49,PTN,STK32A,PTPRD,TUG1,ZNF844,PID1,ZNF793,FAM184A,MSANTD2,RFX4,TTLL7,SLC25A36,RNASEL,TMLHE,RAVER2,GSTCD,ROBO2,BAALC,ATP8B4,RTKN,ZNF568,ZNF331,AMER2,FNIP1,HSPA4L,NLGN4Y,PPP1R9A,SH3GL3,PPM1E,FNDC3A,PAAF1,WDR37,RAB3GAP1,SLC8A3,TRIM67,ELMO2,SLC22A4,IFT122,MBD5,SNRPN,TRERF1,TNIK,SOX5,KIF21B,BDP1,FNBP1,ENKUR,HECW1,KDM4C,MCF2L2,SRPK2,ZNF621,SMOC1,SEPT8,KLHL7,NUDT10,COBL,DDHD2,TAL1,ADGRL3,AGTPBP1,TBCEL,FBXW11,TBL1X,DMXL2,TRIM2,ARHGEF12,GPRIN3,AHCYL2,CRB1,AP4E1,HHIP,TLR4,ERCC6L2,TMPO,RIMBP2,KAT6B,TP53BP2,TPM1,RGMB,METTL3,PDSS1,TRO,TTC3,ZKSCAN5,SGK3,CADM1,AMOT,UGT8,ZNF709,VLDLR,CLDND1,ZBTB14,ZIC3,TRIM9,MEIS3,INTS3,EVI5,LMAN2L,PCDH15,GAL3ST3,FAM47E,PARP11,RTN4,UBE3B,JMJD1C,TRAM2-AS1,SSPN,KLHDC1,CBLN2,SENP7" MicroRNA hsa-miR-323-5p:mirSVR_lowEffct hsa-miR-323-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.86E-102 2.17E-98 2.44E-101 2.24E-100 269 1147 "ABHD6,NDRG3,KLHL32,RNF157,SORCS1,UNC5A,ALAD,SPOP,MARCH4,ALK,ANK3,MYH7B,PKP4,KCNAB2,CDK10,TMEFF1,ARRB1,RGS20,PLA2G4C,ASGR1,B3GALT2,DPY19L3,BARD1,KSR1,FUBP1,C1QC,GYG2,CACNA1E,DDR1,KALRN,CANX,VXN,VSTM2A,MAP7,CDC42,SRSF11,SOCS6,CHM,CHN2,KMT2C,FAM19A5,CNTN1,IQCK,FAM149A,ABI3BP,TOGARAM2,CHD1L,SLC35F1,CDC42BPB,SH2B1,GDA,CLIP3,RGS6,SIPA1L1,VCAN,CFAP61,FGFR1OP2,ARHGAP24,LONRF1,IST1,DGKG,POM121,SV2B,SGSM2,SEC16A,CHRDL1,DMD,DNM1,DYNC1I1,TOM1,DNAJB6,ABCC9,EDNRA,ANKRD46,GPR61,EGFR,ABI2,SRRM1,DENND4A,RCSD1,ECSIT,EZH1,HSPA12B,ABCA8,TAOK3,DLC1,ST3GAL6,STRADA,KAT8,GORAB,SLC9B2,FGF13,BAIAP2,AGAP2,ZBED3,ARFGAP2,GPR153,NSG1,GAD1,GFER,BRD8,CRCP,TOX3,MSL3,OS9,INSM2,GNAL,PRUNE2,RAPGEF1,PLCD4,GRID1,SPACA9,NR3C1,GRM2,BTN2A1,RNF165,AP4S1,GYG1,AGBL5,LRRC75A,SHISA6,EID2B,IFI16,MYLK2,ZIC5,LRRCC1,ITGAM,JAK1,OLFM3,KCNC1,KCND2,KCNJ3,KCNMA1,KLRC2,LIMS1,PAXBP1,MBNL1,MDM4,PPM1L,COL28A1,PTOV1,MYCN,MYO7A,ZNF862,NCAM1,NCAM2,NFE2L2,NINJ2,NNAT,SMIM11A,NTRK2,NUCB2,OCRL,GLIPR1L2,PBX1,PCMT1,PCSK5,GDAP1L1,SLC25A23,ZNF426,PURG,RC3H2,SCHIP1,PPP1R1A,RANBP3L,MAPK7,MAPK9,PSD,MDGA2,WDR25,UHRF1BP1,RAD51D,RAD52,ZCWPW1,ROGDI,MSANTD2,RET,GTDC1,ARHGEF10L,MRPS18A,CCDC82,GSTCD,ROBO2,CCDC102B,SNX22,NEK11,KIAA0895L,TCP11L1,CNTNAP3,MEG3,WLS,RTKN,SATB1,ATXN1,SCN8A,PRCD,ITSN1,KIF16B,ST3GAL3,ZNF365,SMTN,SLC6A1,PKNOX2,LRRC55,SLC6A7,SLC15A2,ELMO2,SMARCE1,INAVA,RIMS1,MBD5,MYO16,WDTC1,SP4,PEG10,ZC3H13,TSPYL2,ATP10B,POGZ,ITPRID2,NKAIN2,LRRC4,FCHO1,SEPT8,GANAB,AJAP1,RHBDL3,COBL,CAMSAP2,FAM208A,UNC5D,CNTN2,VWA3A,WSCD1,TCF4,TCF7,RPGRIP1L,AZIN2,PCDHB3,ATP13A2,SLC44A1,TJP1,KCTD2,TNS1,SEZ6L,ZNF346,PDSS1,RUSC1,UBTF,MTCH1,PLPPR2,BEST1,WIPF1,CLDND1,LGI4,ZNF154,POLR3H,AMZ1,ZNF213,RNF103,ADAMTS9,NAV3,PCBP4,ST7,UBE3B,KAT6A,CASC15,FAM219B,ST8SIA2" MicroRNA hsa-miR-424*:mirSVR_lowEffct hsa-miR-424*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.69E-102 3.20E-98 3.59E-101 3.30E-100 247 971 "SYS1,CSMD3,TMEM132B,SORCS1,KIDINS220,SLC44A5,PCDH19,TAOK1,CEP126,ALK,AMPD2,AMPD3,KIF6,BIN1,ZFAT,PPFIA1,AMER3,APP,TMEM263,ASPH,RNF182,ADGRB3,BMP7,CACNA1G,C5,CACNA1B,THSD7A,CAMK2A,BRSK2,SPAG9,CCNH,SCARB1,ZBED1,CDC42,CDH10,MAGI1,CNOT8,QKI,PCYT1B,AKAP6,BTF3L4,SLC4A8,COX4I1,ZFP28,NRG2,CHD1L,AKAP12,GDA,CS,SIPA1L1,KIAA0040,PLCXD3,GREB1,ST18,BOC,KATNAL2,RIPOR2,TBC1D5,IST1,TOMM20,DBN1,ZBTB24,C2CD2L,LYPD1,RHOBTB1,PLPPR4,WDR20,DMPK,CDON,ARRDC4,DNAJB6,FSD1L,PHF20L1,TENM1,PCOLCE2,CALCRL,USPL1,EPB41,EPHA5,ERBB2,ZNF549,MRPL37,CDKL3,MRVI1,F8,FAM198B,WAC,TMEM132C,CEP78,CHST15,SPSB4,PRKAG2,FHL1,SYNCRIP,FOXO3,FLT1,NBEA,ATP6V1H,ZNF605,DACH2,NEURL4,STAG2,CHL1,GABRB1,GALC,NCKAP1,DNER,ALDH1L1,COPS8,GNG4,PRLHR,CECR2,GRB10,GRIA4,LINC01551,RABL2A,ZHX1,NEGR1,C5orf24,PLD5,ZNF385B,KCNK2,IPO5,STXBP5,MBNL1,MEST,MITF,AFF1,MMP16,NEXMIF,ZNF862,MYT1,NF1,NFYA,CNOT4,SLC11A2,NRCAM,IGSF11,PBX1,PCSK5,PDE4D,GNG2,BEST3,PFKFB2,OLA1,GPSM2,PDZRN4,LRP12,ING3,MED1,CRLS1,PPP2R5C,PPP3CB,GRAMD1C,DIRAS2,PRPSAP2,PIGG,CNTLN,PLPPR1,PTN,TMEM260,TMEM145,MARCH1,PID1,SUSD4,RASGRF2,KHDRBS2,SLC6A15,ZYG11B,GTDC1,RFX3,RGS12,SLC25A36,SUGCT,ROBO1,ROBO2,TMEM100,ARMH4,SPIN3,MCMBP,PAQR6,HUNK,CLIP1,SAFB,SATB1,SELL,GALNT10,FOXRED1,SUPT20H,SCAF8,SYBU,NLGN1,SMTN,PKNOX2,SLC8A1,SLC8A3,BTBD7,INAVA,SNRPN,UNC80,SOX2,ZHX3,CDK19,TAB2,SMOC1,GANAB,MLC1,VPS13A,ANKRD12,MCF2L,UNC5D,ALG1,VWA3A,TCF4,TCF7L2,TCF12,PUM2,ZNF106,TJP1,BHLHB9,ZFP91,RIMBP2,KAT6B,TPM1,TTTY15,AMOT,VLDLR,NPDC1,RICTOR,TCEAL7,REEP1,FSTL5,INTS3,WNK1,CA10,PRTFDC1,SLC38A1,PRDM8,PCDH15,WNK3,C12orf4,DNAH10,PHTF2,ZNF248,SSPN,SOCS4,SLC4A10" MicroRNA hsa-miR-346:mirSVR_lowEffct hsa-miR-346:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.90E-102 5.56E-98 6.22E-101 5.73E-100 268 1143 "GALNT16,BRAP,SLC12A5,PTCHD1,SLC24A4,ZNF608,SNX32,HACE1,DISP3,TXNDC16,ALAD,CARNS1,PDZD4,AMT,CCDC146,PPFIA4,PHF12,PPFIA1,EPB41L5,BCAS1,ARNTL,ARRB1,ALDH4A1,MYOM1,KSR1,SYNJ2,FUBP1,SCAPER,MMD2,CACNA1D,CABP7,PTBP2,TRIM41,VXN,BRSK2,MAP7,RGN,REPS2,LRRFIP1,CHGB,CASC2,MS4A7,RAB28,TJP2,NIPBL,SLC4A8,CRHBP,NCOR1,CLIP3,SEC24C,ARHGEF10,VCAN,PPP1R16B,NRSN1,RUBCN,FAM131B,CYBB,RASSF2,INTS1,DGKG,DAPK1,DCC,C8orf34,HEPH,CEP170,LYPD1,RHOBTB1,DLG2,SLC29A4,CPEB2,DMTF1,DTNA,ECM2,E2F5,WDPCP,ANKRD46,HIPK3,CNNM1,PHF20L1,MRO,MBNL2,TENM1,BSCL2,DCTN4,EPHB1,DENND4A,NCALD,EFS,MRPL37,EYA1,MRVI1,F5,FABP7,RACK1,FCGRT,GORAB,FER,SPSB4,FGF14,BAIAP2,SUCO,AGAP3,CINP,UFM1,ZNF605,KHDRBS3,CGREF1,NSG1,DKK3,GABRA5,GABRB1,GABRG1,DISC1,INPP5K,SESN1,ADAM28,GHR,HPGDS,TOX3,ZNF638,GNAS,WDFY3-AS2,ADGRA3,PRRC2B,GPD2,ATF7,EML4,RAPGEF4,STMN2,RFFL,ADAMTS8,CLASRP,RNF165,GSTM5,RABL2A,ADAMTS6,WIF1,ZDHHC15,OPALIN,FAM95B1,DOCK7,LRRCC1,HES5,DIPK1A,CDH20,KCNJ9,KIF5A,KIF5C,KLRC3,CAMK2N2,STMN1,INSYN2,LIG4,MAP6,TM6SF1,MEIS1,DBNL,MT3,PABPC1L2A,NELL1,NME4,NODAL,NUCB2,SETD4,IGSF11,PDE4A,PDE4D,PDGFRA,PDPK1,PFKFB3,JAKMIP1,PMP22,SCHIP1,ING3,CCDC144B,PRKAB2,RAB39A,GRAMD1C,MASP1,QRICH1,PIGG,BDNF-AS,PTN,STK32A,PTPN13,EML5,USP47,RAP1GAP,SUSD4,SLC6A15,RET,SLC25A36,PBRM1,CARF,RORB,ARMH4,SPIN3,ZNF671,ATP8B4,MEG3,ABCA11P,NCBP3,ST6GAL1,SLITRK3,ST3GAL3,FAM81A,PKNOX2,SLC6A8,CPEB4,ZFP1,LIMCH1,SNRPN,HECW1,SPART,NFASC,MESP1,EPB41L3,NCDN,SEPT8,ARHGEF9,NUDT10,ADAMTS17,ATP11A,ANKRD12,SEMA4A,TAL1,ADGRL3,KLHL4,TCF4,NEU4,TCF7L2,FRYL,DICER1-AS1,CHST8,CRB1,ZMAT3,AKTIP,CDH22,ERCC6L2,CSMD1,NPL,C9orf85,ZNF346,PPIL6,DCBLD1,HEPACAM,UBE2H,UBTF,MTCH1,LAT2,ETNPPL,LGI4,ZIC1,CFAP52,AGMO,POLR3H,MEIS3,INTS3,SLC38A1,VPS35L,PCDH15,NAV3,URM1,FAM47E,PCBP4,DOCK8,TMEM63C,IFT88" MicroRNA hsa-miR-200a-3p:TargetScan hsa-miR-200a-3p TargetScan 1.04E-101 5.82E-98 6.51E-101 5.99E-100 203 651 "C3orf14,NCKAP5,ADD3,KIAA1211,MTA3,OSBPL1A,OSBPL6,AMPD2,OGT,ANK2,APBB2,MIER1,IGDCC4,ARNTL,CDK13,DNAH17,ATP2A2,NRP2,CACNA1I,GPC2,LDLRAD4,CACNA1E,CACNA2D1,CANX,CDC25B,LONRF2,CDC42,CDH10,EVI5L,NUMBL,CFL2,FOXN3,PLEKHB1,KMT2C,PPT2,KIAA1549L,NRXN1,QKI,HECTD1,MAP4K4,NIPBL,CNTN1,MYRIP,CLOCK,CDC42BPB,CRMP1,ANKRD44,CSNK1G3,NCAN,PLXNA4,ERC2,PLCXD3,CTNND2,KIAA0408,DOCK4,ARHGAP24,HDAC4,MATR3,DAPK1,CEP170,MAGI2,RHOBTB1,G3BP2,CHRDL1,DLG3,GRIN3A,CDON,HIPK3,FSD1L,PLXNC1,EIF5,ELAVL2,ELAVL4,RGS17,GPHN,IGSF6,KATNAL1,DLC1,ATP8A1,OLFM1,FGF13,CAMSAP1,ANKFY1,KHDRBS3,CELF1,MSANTD4,PHYHIPL,GAB1,FAM184B,GAD2,NEK6,ATP8A2,FAXC,GCNT2,RAB30,GPR75,CBX1,KIAA1958,KDM2B,GPD1,GPM6B,GPR12,GRIN2D,NR3C1,KIF3A,RASSF8,NXPH2,KLF12,BACH2,MIER3,HLF,ACOT7,HMGB1,HNMT,AGFG1,HTR2A,MSL1,KCNC2,IPO5,LSAMP,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,AFF1,MMP16,MN1,CCDC80,MDGA1,MYO5A,MYO9A,NAP1L1,NCAM1,NFIA,NPTX1,NRCAM,HCN1,P2RY1,GPR137C,PBX1,PCDH8,PLCL1,EPN1,SCHIP1,NXPH1,POU3F2,PPP2R2B,PPP2R5E,PRKACB,PTCH1,PXK,PTPRD,PTPRG,PEX5,MARCH1,KHDRBS2,ATXN1,ATXN7,SCN7A,ELMOD1,SCAF8,ITSN1,PPM1E,CHD9,DZIP1,ATF7IP,CPEB4,CXXC4,RCOR3,RIMS1,MBD5,FAM126B,PDZD2,MYT1L,KDM3A,HECW1,NPAS3,NFASC,LMO3,CLASP2,MPRIP,FAM168A,NECAB1,EXOC7,CAMSAP2,CBX5,ASXL3,LRRC8A,KAT6B,NR2C2,CADM1,PITPNB,BCL2L13,CLIP2,LYPD6,CADM2,PRDM10,MVB12B,RGS7BP,CERS6,JMJD1C,FRMD6" MicroRNA hsa-miR-141-3p:TargetScan hsa-miR-141-3p TargetScan 1.04E-101 5.82E-98 6.51E-101 5.99E-100 203 651 "C3orf14,NCKAP5,ADD3,KIAA1211,MTA3,OSBPL1A,OSBPL6,AMPD2,OGT,ANK2,APBB2,MIER1,IGDCC4,ARNTL,CDK13,DNAH17,ATP2A2,NRP2,CACNA1I,GPC2,LDLRAD4,CACNA1E,CACNA2D1,CANX,CDC25B,LONRF2,CDC42,CDH10,EVI5L,NUMBL,CFL2,FOXN3,PLEKHB1,KMT2C,PPT2,KIAA1549L,NRXN1,QKI,HECTD1,MAP4K4,NIPBL,CNTN1,MYRIP,CLOCK,CDC42BPB,CRMP1,ANKRD44,CSNK1G3,NCAN,PLXNA4,ERC2,PLCXD3,CTNND2,KIAA0408,DOCK4,ARHGAP24,HDAC4,MATR3,DAPK1,CEP170,MAGI2,RHOBTB1,G3BP2,CHRDL1,DLG3,GRIN3A,CDON,HIPK3,FSD1L,PLXNC1,EIF5,ELAVL2,ELAVL4,RGS17,GPHN,IGSF6,KATNAL1,DLC1,ATP8A1,OLFM1,FGF13,CAMSAP1,ANKFY1,KHDRBS3,CELF1,MSANTD4,PHYHIPL,GAB1,FAM184B,GAD2,NEK6,ATP8A2,FAXC,GCNT2,RAB30,GPR75,CBX1,KIAA1958,KDM2B,GPD1,GPM6B,GPR12,GRIN2D,NR3C1,KIF3A,RASSF8,NXPH2,KLF12,BACH2,MIER3,HLF,ACOT7,HMGB1,HNMT,AGFG1,HTR2A,MSL1,KCNC2,IPO5,LSAMP,MARK1,MBNL1,LRP1B,MEIS2,PPM1L,AFF1,MMP16,MN1,CCDC80,MDGA1,MYO5A,MYO9A,NAP1L1,NCAM1,NFIA,NPTX1,NRCAM,HCN1,P2RY1,GPR137C,PBX1,PCDH8,PLCL1,EPN1,SCHIP1,NXPH1,POU3F2,PPP2R2B,PPP2R5E,PRKACB,PTCH1,PXK,PTPRD,PTPRG,PEX5,MARCH1,KHDRBS2,ATXN1,ATXN7,SCN7A,ELMOD1,SCAF8,ITSN1,PPM1E,CHD9,DZIP1,ATF7IP,CPEB4,CXXC4,RCOR3,RIMS1,MBD5,FAM126B,PDZD2,MYT1L,KDM3A,HECW1,NPAS3,NFASC,LMO3,CLASP2,MPRIP,FAM168A,NECAB1,EXOC7,CAMSAP2,CBX5,ASXL3,LRRC8A,KAT6B,NR2C2,CADM1,PITPNB,BCL2L13,CLIP2,LYPD6,CADM2,PRDM10,MVB12B,RGS7BP,CERS6,JMJD1C,FRMD6" MicroRNA hsa-miR-708*:mirSVR_highEffct hsa-miR-708*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-101 8.54E-98 9.53E-101 8.78E-100 271 1170 "RALGAPA1,CLK4,ADD3,SORCS1,PWWP2A,ADORA3,KIDINS220,AP2A2,ZNF608,RTL9,HACE1,NME5,TAOK1,LRRC7,SPOP,UNC79,FAM135A,ZNF687,LRCH2,SHROOM2,AQP4,MIER1,TMEM263,CDK13,RNF182,ATP6V0A1,ADAM23,SEC11C,DST,OSGIN2,CA8,CAMK2A,CAST,CLDN10,RGN,CDC42,CDH2,LGI1,SRSF11,SOCS6,CHM,PLAA,KIAA1549L,COG1,MAP4K4,SLC25A27,BTF3L4,RCHY1,AHCTF1,FAM171B,NCOR1,SIPA1L1,UBXN2A,CFAP61,ZSCAN23,DGKB,TMEM170A,SCRN1,PLEKHM1,COPS7A,BLOC1S6,DDX46,RHOBTB1,SV2B,G3BP2,CHRDL1,DPP6,RCAN1,DTNA,DTNB,DNAJB6,EDIL3,FCF1,FSD1L,FAM13A,PHF20L1,PLEKHA1,C3orf18,C8orf37,EPB41,ETV1,RASL12,EZH1,CEP78,KIAA1109,FGF14,FGR,SUCO,MEX3B,FOXF2,PCYOX1,FOXO3,SMC2,KHDRBS3,DACH2,STAU2,OGA,PHYHIPL,ZMAT1,MEGF10,GABBR1,GABRA1,GABRB1,GAD1,HBS1L,RAPGEF6,DISC1,SULT1C4,PPARGC1A,DBF4,GLS,HTATSF1,MAP7D2,RAB40B,GNAO1,GPD2,GPM6A,ATF7,FUT10,EML4,GRIA2,PRDM5,LINC00839,PSIP1,NXPH2,BACH2,HMGB1,SCRG1,HMGCR,HNF4G,SHISA6,GAREM2,PLD5,IGSF1,LRRTM3,ITGAV,JAK2,OLFM3,KCNC1,KCNJ16,SYTL4,NCOA7,SMAD9,MAOB,MARK1,MAT2A,MATN3,MBNL1,LDLRAD3,MEIS1,AFDN,ERICH3,MRPL42,RSPO2,MXI1,PABPC1L2A,P2RY13,NOS1,CLEC9A,HCN1,CHAMP1,P2RY1,GLIPR1L2,FTO,PRIMPOL,PDZRN4,STRN3,PSAT1,ING3,EPB41L4B,PILRA,PPP2R5C,PRKACB,MAPK10,HYDIN,PRPH,VPS13C,SIDT1,QRICH1,PLPPR1,MTMR10,PTPRO,PTPRZ1,PEX5,USP47,SH3TC2,NWD1,OXR1,DBX2,GTDC1,FIGN,RFX3,PBRM1,ZFHX4,C12orf49,CARF,CCDC25,FBXW7,SPIN3,ATP8B4,TRAPPC13,RMI1,SEMA6D,IL17RB,HSPA4L,CPEB3,MAGI3,ST6GAL1,EPN2,KANSL3,RAB3GAP1,CDK5RAP3,SLC9A5,ZFP1,DMRTC1,SMARCE1,SNAP25,RBM34,NMNAT2,CAND2,SPP1,CLASP2,EPB41L3,ZC4H2,LARP4,SS18,ERBIN,STAU1,CEP68,TTBK2,DIP2A,VPS13A,SYT1,MTCL1,DDHD2,UNC5D,ZEB1,RPGRIP1L,WDR7,AHCYL2,HIF3A,TEX15,AKTIP,TJP1,BHLHB9,ERCC6L2,HEY2,DAAM2,BEX4,PRMT8,TRH,NEIL2,STXBP4,TSC1,TMEFF2,SGK3,CADM1,MEAF6,WIPF1,SLC13A3,ZNF708,TRIM9,CADM2,RNF103,PCDH15,PLSCR4,GOPC,HNRNPA3,RNF170,KLHDC1,IFT88" MicroRNA hsa-miR-1298:mirSVR_lowEffct hsa-miR-1298:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-101 9.15E-98 1.02E-100 9.40E-100 256 1047 "RALGAPA1,ACADM,SORCS1,PTCHD1,OSBPL6,FAM135A,AMPD3,LRCH2,PKP4,PARG,APC,BCAS1,API5,ARNTL,RGS20,CAPRIN2,ASPH,ZBTB10,ATP1B3,ATP2B1,ATP2B2,ZNF583,RNF182,ADAM23,RGS9,BID,DST,ARHGEF7,JAZF1,SGCE,C5,CA8,RUNX1T1,CBR1,NOG,RCBTB2,CHN2,KMT2C,EPS15L1,NRXN3,NGEF,QKI,NIPBL,AKAP7,AKAP6,COL4A5,IGDCC3,CP,CREM,VCAN,CTH,NRSN1,RIMS2,CCDC144A,CYBB,DOCK4,FGFR1OP2,KCTD8,PITPNC1,C8orf34,ZEB2,MAGI2,SPOCK3,SRGAP3,KBTBD11,DLX1,RAB39B,DMD,DPH1,DTNA,EDN3,HIPK3,EGFR,EGR3,EN2,EPS8,WAC,FABP7,CACNG3,DLC1,CEP78,FCGR3A,TOMM40L,SEC24B,SUCO,ANKFY1,SGIP1,SLC37A3,EFCAB2,TACC2,TMEM107,STAU2,TBR1,AHCYL1,IQGAP2,GAP43,NFU1,ADAM28,BRD8,TTBK1,HPGDS,GLI2,LUZP2,FERMT2,ADGRA3,FUT10,B4GALNT4,EML4,GPR37,RAPGEF4,GRB10,GRIA4,GRID1,NR3C1,PRDM5,GRM7,RABL2A,SOX21,PSIP1,FRMD5,GABARAPL2,HTR5A,IRF8,MSL1,IGF1,ZIC5,RBPJ,IL11RA,IL12A,BRINP3,OLFM3,LINC00634,LIMS1,PAXBP1,VWA5A,ZNF667-AS1,MAOB,MATN3,MEIS2,MEST,KCTD6,MMP16,ERICH3,CTNNA3,MTTP,NAP1L1,SFR1,NEFH,NELL2,NF1,OTOGL,NOVA1,OPHN1,ETFRF1,GNG2,GPSM2,JAKMIP1,PLIN1,PRRX1,SPATA6,PPM1B,DIRAS2,KLK6,VPS13C,MDGA2,TMEM104,QRICH1,PTK2,STK32A,OCIAD1,PTX3,TUG1,PID1,CEP97,FAT4,RBBP6,VEPH1,GAL3ST4,ZMAT4,REV3L,UBR7,DCUN1D2,GSTCD,ROBO1,NEK11,FBXW7,ADAL,RPS6KA2,ATAT1,NCBP3,FAM182A,TRAPPC13,RMI1,LRRTM4,ZFP2,GALNT10,KIF21A,PPM1E,FNDC3A,NLGN1,PAAF1,WDR47,CCDC88A,CPEB4,SNRPN,ERC1,KIF1B,RBM26,SRPK2,TROVE2,ITPRID2,ZNF302,NKAIN2,KANK1,KLHL7,FGD4,SYT1,MTCL1,ALG1,AGTPBP1,ZEB1,RPGRIP1L,WASHC4,PCDHA5,HIF3A,FAM200B,SIRT1,AP4E1,ACTR6,SEZ6L,TRIO,TRPS1,TTPA,CADM1,EIF4ENIF1,UBE3A,PLEKHH2,VLDLR,ZNF32,TRIM9,FMN2,GPR158-AS1,LYPD6,REEP1,ANKS1B,CA10,EVI5,FIP1L1,SLC17A6,FAM13C,AMN1,PAK5,RNF170,ZDHHC20,FXR1,IFT88" MicroRNA hsa-miR-627:mirSVR_lowEffct hsa-miR-627:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.79E-101 1.00E-97 1.12E-100 1.03E-99 299 1413 "ABAT,ABR,EMILIN3,NCKAP5,NBAT1,KLHL32,TMEM132B,ADD2,BRAP,PWWP2A,SLC24A4,SPOP,TNRC6C,LGR5,AQP4,MARCH3,EIF4G3,ATP1B3,CADM3,DPY19L3,BBS2,DCAF5,CFLAR,BMPR1B,BAIAP3,LDLRAD4,CACNB4,CAMK2G,VXN,RUNX1T1,MTMR7,REPS2,CDH2,TIGD7,JAM2,SLIT2,NRXN1,TPP1,FAM19A5,QKI,MAP4K4,LY86,CNTFR,FAM149A,COL4A5,TBPL1,CHD1L,C1QL2,SNCAIP,TENM4,CSF2RA,FEZ1,MICAL2,CNTNAP2,PPP1R16B,KIAA0040,UBXN2A,ST18,RUBCN,DOCK4,ARHGAP32,KATNAL2,ARHGAP24,DGKG,AIF1L,ARMCX4,YTHDC1,HEPH,KIAA0753,RUSC2,COPS7A,CEP170,LYPD1,SPOCK3,FAM107B,KIF19,SEC16A,EXOG,DYNC1I1,CDON,DNM2,DTNA,DYRK1A,EBF1,EDNRA,EDNRB,FRY,SIDT2,YAF2,APH1A,KMT5B,GOLGA7,TENM1,STARD3NL,USPL1,EPB41L2,RASGRP2,EPHA5,ENPP6,STX2,ZNF549,ETV1,VPS26C,FABP7,EFEMP1,TESK2,ZNF589,GORAB,KIAA1109,OLFM1,FLYWCH1,SYT3,C2orf88,JKAMP,UFM1,KHDRBS3,CELF1,B3GAT1,HHIPL1,DKK3,MEGF10,HBS1L,GALC,SALL3,ZNF559,DISC1,SRRM4,KIAA1841,ALDH1L1,GFAP,PCDH17,TCERG1,LILRB4,GPD2,NUDT21,GRIA4,GRIN2C,GRM2,PRDM5,GRM7,ZBTB45,GUCY1B1,ATOH8,RASSF8,FRMD5,HMGB1,CPT1C,ZNF546,DOCK7,LRRCC1,LRRTM3,KCNJ5,KCNK3,KCNMA1,CREG2,STXBP5,LAMA2,HECTD2,NCOA7,LSS,PIK3AP1,SHC3,MIA2,MSR1,CTNNA3,MYO7A,ZC3H12B,NDP,NF1,NFE2L2,NHLH1,NPTX1,SMIM11A,HCN1,OPHN1,P2RX7,SNTG1,PC,PCSK1,PCSK5,PDE3B,PDE4D,PDPK1,A2ML1,XRN1,KCTD15,ST8SIA5,JAKMIP1,FTO,PMP22,MAPKAP1,MAGEL2,POLG,PPP2R5C,PKIA,SLC22A23,TMEM104,PIGG,TMEM260,PTPRB,OCIAD1,SUSD4,ROGDI,RASGRF2,DBX2,ZMAT4,REV3L,ERI2,MORC4,UBR7,RLBP1,SLC25A36,RIC8B,PBRM1,RNASEL,ARMC5,ROBO2,CCDC102B,MRAP2,SPIN3,ATP8B4,NLGN4Y,FBXO11,ST6GAL1,SLITRK3,NLGN1,ST3GAL3,ANKRD6,FAM214B,YPEL4,CCDC88A,SLC12A2,ELMO2,BTBD7,NAXD,ZNF667,SORCS3,UNC80,SCN3B,BDP1,SOX11,NMNAT2,UHRF1BP1L,TSPYL2,NPAS3,SRPK2,NKAIN2,ZSCAN29,DIP2A,PHLDB1,KANK1,STXBP1,RHBDL3,VPS13A,FNDC9,ANKRD12,AGTPBP1,SATB2,TPCN2,PHF24,TMEM151B,FAM189A1,HIF3A,AP4E1,TGFBR3,FAM124A,BEX4,RIMBP2,SEZ6L,RASD2,DOK6,SYNPO2,AMACR,TUB,TMEFF2,DNAJC12,SLAIN1,VLDLR,TBC1D15,KLC2,SLC13A3,CFAP52,LYPD6,ZBTB38,TMEM198,ANKS1B,INTS3,EMSY,DNALI1,STMN4,STOX2,ADAMTS9,PCDH15,NAV2,LINC00632,WIPF2,ZNF248,ST8SIA2,FAM198A" MicroRNA hsa-miR-206:mirSVR_highEffct hsa-miR-206:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.97E-101 1.10E-97 1.23E-100 1.13E-99 273 1188 "RALGAPA1,CLK4,ABHD6,KDM5D,NDRG3,ADAR,SLC24A4,HACE1,ALCAM,ARHGAP20,AMPD3,OGT,CCDC146,MAP4K3,UPRT,ALS2,API5,MIER1,ASPH,TMEM108,ZNF582,FGF17,BMPR1B,SYNJ1,FUBP1,IL33,CA8,KALRN,SEPT7,CDC42,LGI1,L3MBTL4,MAGI1,UBE2L6,CLCN3,CLTC,C4orf33,CNN3,COL4A5,SLC4A8,AHCTF1,BAG4,SLC35F1,CREM,CREB5,RNF14,C1QL2,CRYM,PDE4DIP,DZIP3,DCAF8,MATR3,KCTD8,DGKB,YTHDC1,JAKMIP2,ELMO1,TIAM2,HP1BP3,SMG7,PLPPR4,DLX1,DRD1,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,SYT15,MRO,KMT5B,BSCL2,TMEM35A,EN2,EPHB1,KCNMB2,RABEPK,MRPL37,CDKL3,ADGRV1,CEP78,CHST15,FER,POLR1B,FGFR1,SEC23B,IP6K2,ANKFY1,NELFCD,AKAP3,NBEA,UFM1,DACH2,CGREF1,ST6GALNAC3,FYB1,GABRA3,ILDR2,DENND2A,GAD2,HIGD1B,ZNF559,LRRC37A6P,KIAA1841,ARFIP1,PCDH17,PPARGC1A,MALT1,GLS,FERMT2,WDFY3-AS2,ADGRA3,GPD2,GPR17,MCHR1,ZNF496,RNF165,LINC01551,AP4S1,PSIP1,MAEL,RASSF8,HMGCR,HNRNPK,ZDHHC15,HSP90AA1,IDH3A,IGF1,LIX1,DIPK1A,INSM1,SLC35G1,METTL21A,KCNK2,KIF2A,STXBP5,KTN1,LAMP2,PAXBP1,MAP2,MEIS1,MRPL42,SCG3,MYO9A,PABPC1L2A,NEUROD1,SLC11A2,HCN1,NTRK3,ZNF713,GPR137C,SNTG1,PDCD2,PIRT,PDGFRA,ENPP2,CDK14,GDAP1L1,NALCN,KCTD15,PURG,TRHDE,SCHIP1,MED1,MINDY2,PRKACB,MAPK3,GRAMD1C,HYDIN,PLPPR1,TMEM260,ZIK1,OCIAD1,PTPRG,MSANTD2,SLC6A15,CRTAC1,RGS7,RIT2,RNF220,SLC25A36,NUDT11,EXD2,C12orf49,CARF,ROBO2,RPL15,FBXW7,ACER3,KCNIP3,ZNF568,AP1AR,SCP2,ASRGL1,MRAS,TRA2B,ITSN1,SH3GL3,FNDC3A,ANKRD6,ZNF365,PEX26,SLC6A11,SLC8A1,RAB3GAP1,SLC15A2,SORCS3,ANKRD36,SNAP25,SNRPN,USP33,SOX5,SP2,NPAS3,SAMSN1,LARP4,SS18,NXT2,STAU1,ACSBG1,SYN2,TACR1,ALG1,WWC1,ANO4,TCF7,TRIM2,CLASP1,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,LRRC8A,SEZ6L,NPL,TPM3,SYNPO2,TRIO,AMACR,RFTN2,TTC3,RPL7L1,FAM155A,UBE2H,AMOT,TBC1D15,LMF1,WIPF1,ZFP37,WNK1,STOX2,TMEM178A,HPS4,SLC17A7,WNK3,SLC17A6,PARP11,PHTF2,ADAMTSL3,TIGD6,MSRB3,NETO2,SLC4A10" MicroRNA hsa-miR-4308:mirSVR_lowEffct hsa-miR-4308:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.90E-101 1.63E-97 1.81E-100 1.67E-99 295 1380 "ACADM,EMILIN3,CSMD3,KLHL32,SLC12A5,SORCS1,PTCHD1,DPY19L2P4,ZNF578,ALAD,KIF6,AMT,ANK2,SEMA7A,CCDC146,PPFIA4,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DGKZ,AQP6,KIAA1614,ARNTL,ARRB1,PLA2G4C,ALDH4A1,ATP1A2,N4BP2L1,ATP6V1G2,TTLL9,TTC9B,ADGRB1,DST,C1QC,IL33,MMD2,CALB1,CANX,MAP7,RUNX1T1,LDB2,METTL6,AP4M1,LGI1,LARGE1,IGFN1,UBE2L6,CNOT8,C4orf33,MAP4K4,PCYT1B,COX4I1,AHCTF1,TOGARAM2,MYRIP,CHD1L,CPS1,CLOCK,C2CD2,RBM39,TENM4,MICAL2,OSBPL3,PPP1R16B,ERC2,CMTM5,CTH,RUBCN,NOS1AP,ARHGAP24,FRMPD4,EARS2,DAPK1,DCC,C8orf34,COPS7A,KBTBD11,GRIN3A,FAM57B,DTNA,DNAJB6,WDPCP,PHC2,YAF2,SH3GLB1,SUGP2,APH1A,ABI2,RASA4,ELN,USPL1,EPB41,EPB41L1,RCAN2,EPHA5,GPHN,VPS26C,EXTL1,ECSIT,PTK2B,FCGR3A,TOMM40L,GORAB,FGF11,FGFR3,SCARA3,FOXG1,EVL,DPYSL4,NBEA,CAMKK2,ZNF605,MPP6,GABRB1,GAD1,AHCYL1,BRPF3,INPP5K,SRCAP,GFAP,GFER,MMADHC,KIRREL3,TTBK1,GLYR1,STARD3,KCNMB4,GOLGB1,SERP2,GRM1,GRM7,LINC01089,MFSD2A,SOX21,LINGO1,RNFT2,FAM222A,TOX2,ARHGAP36,AGBL5,HSD17B1,HTR5A,RBPJ,C2CD4C,KCNJ11,KIF5C,HECTD2,PIK3AP1,ZFYVE27,MAT2A,ADAM11,MEIS2,PPM1L,MSI1,MYO7A,RTL5,NCAM1,NELL1,PCBP3,OPCML,P2RX7,PDE1C,PDE2A,PDE4D,GNG2,PFKFB4,OLA1,SSH1,FAM218A,TMEM38A,ST8SIA5,PLCL1,LRP12,ING3,POU3F2,POU6F1,MINDY2,PPP1R1A,PPP2R5C,GRAMD1C,SLC22A23,WBP1L,GON4L,CNTLN,MTMR10,PTPRB,PTPRE,C1orf109,PEX5,ZSCAN2,CEP97,SH3TC2,ROGDI,ZDHHC14,RDX,RET,PRIMA1,KCTD17,RIC8B,RNASEL,RNH1,TMLHE,CYB561D1,RPE65,SNX22,RPL15,ACER3,EMID1,MEG3,STX1B,CCDC112,AP1AR,FOXRED2,MIR124-2HG,FAM19A1,LINC00461,PRCD,SMPD3,SOX6,TRIM46,KIF27,FERMT1,ASAP3,WDR37,RPH3A,WDR47,FAM214B,RAB3GAP1,CCDC88A,TRIM67,SLC12A2,SLC14A1,EFHD1,NAXD,GKAP1,SMARCC2,CMTR2,SNRPN,UNC80,SON,KIF21B,SMOC1,NCDN,SEPT8,ADHFE1,GSE1,FAM168A,SYN2,SYP,TACR1,SEMA4A,ANO4,NAT16,TMEM151B,AKNA,AHCYL2,CYB561A3,C18orf54,TIAM1,DDHD1,ZFP91,FAM124A,RBFOX2,CDK20,NPL,WBP2,SYNPO2,PRMT8,NEIL2,FNDC5,KCNE5,FAM155A,AMOT,UGT8,SLAIN1,WIPF1,PORCN,CLDND1,RICTOR,PLPP4,CRB2,CELF4,REEP1,FSTL5,SLC38A1,LINC02210,SEMA3B,WIPF2,UBE3B,KAT6A,NUP214,VANGL2,SSPN,LAS1L,PRRT4,FAM198A" MicroRNA hsa-miR-1179:mirSVR_highEffct hsa-miR-1179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.04E-101 1.71E-97 1.90E-100 1.75E-99 264 1115 "RBM10,CCDC85A,ADD3,SLC12A5,CDC7,ERMN,KIDINS220,ZNF608,PCDH19,WDR35,HFM1,LRRC7,SPARCL1,ALCAM,GPRASP2,ZFAT,OGT,DPP10,LRCH2,CNIH2,TNRC6C,SEMA4G,TMEM263,ARHGAP5,ARNTL,ASCL1,ADAM23,ADGRB3,BBS2,RGS9,ZNF599,CFLAR,SCAPER,WASF1,CACNA2D1,THSD7A,CANX,PRC1,CD38,LRBA,CDC27,LGI1,MAGI1,CHGB,B4GALT6,SLIT2,CPNE6,NRXN3,CLTC,ZFP28,FAM171B,RBM39,ANKRD44,CS,SNCAIP,VCAN,DZIP3,UBXN2A,ARHGAP24,DBI,DCC,MYEF2,BLOC1S6,GSDME,PLPPR4,RABGAP1L,WDR20,DOCK2,ECM2,DNAJB6,DNM1L,E2F5,SYT15,CELSR3,FAM13A,CALCRL,TUBD1,LRRC17,CEP85L,RRAGB,NSRP1,SCML2,TOMM40L,GORAB,KIAA1109,FGF11,FGFR1,POLK,KHDRBS3,STAU2,MSANTD4,SARAF,OGA,HRASLS5,GABRG2,TRAF3IP2,CAB39,GALC,NCKAP1,ZNF559,GATM,GHR,PPARGC1A,GK,GLI2,RAB30,TOX3,OS9,GNAO1,FERMT2,ADGRA3,PRUNE2,GPM6A,ATP2B1-AS1,NR3C1,LINC00839,FAM19A2,IRAK3,INSYN1,MIER3,HMGB1,USP51,SMAP1,IRF8,FAM95B1,SOWAHA,SCIN,LIX1,IL12A,JAK1,KCNA4,KCNJ3,KCNJ16,KCNK2,CYP27C1,PAXBP1,LMO2,VWA5A,HECTD2,NCOA7,PACRG,MEIS1,BLOC1S2,SCG3,NAP1L1,NCAM1,OTOGL,DNHD1,SLC11A2,LOC100128398,GPR137C,GLIPR1L2,PBX1,PCDH9,PDE4D,PDYN,PIK3C2A,FAM218A,PCDH18,SPATA6,SEPT4,MBOAT7,DRAM2,PPM1B,PRKCB,PKN2,EPDR1,RELN,VPS13C,GON4L,SNRK,PTCH1,PTHLH,SPDL1,PTPRB,PTPRO,C1orf109,PPP2R3C,MARCH1,PID1,USP47,BSDC1,GTDC1,RGS3,RGS4,CCDC82,CARF,RPE,RPL15,PTGR2,SYNDIG1,ZNF568,ATXN2,SCN3A,SCN4B,ZFP2,KIF21A,ITSN1,FERMT1,NTNG1,CNKSR2,CTXN2,ZNF430,SEPHS1,SLC8A1,ARHGEF40,BTBD7,SPHKAP,RCOR3,SNAP25,MBD5,SNRPN,PDZD2,MYT1L,BDP1,CLASP2,STOX1,NKAIN2,VPS13A,TACR1,PJA1,CAMTA1,EHBP1,ZEB1,RPGRIP1L,CLASP1,SYNE1,PCDHB9,PCDHB4,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,HHIP,SLC44A1,TLR4,NR2E1,SEZ6L,TPM4,RUNDC3B,RPL7L1,AMOT,SLAIN1,CCDC14,WIPF1,MICU3,KCNT2,TRIM9,ZNF45,SPIRE1,WNK1,TUBA1A,PPP1R3F,WNK3,PDSS2,EPM2A,UBE3B,FRMD6,CBLN2" MicroRNA hsa-miR-660:mirSVR_lowEffct hsa-miR-660:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.46E-101 1.95E-97 2.16E-100 1.99E-99 283 1276 "KCNH8,CLK4,NCKAP5,NDRG3,KLHL32,ADD3,PTCHD1,KIDINS220,BEND6,AP2A2,MTUS1,KCTD16,KIAA1324,AK2,PLA2G6,C1QTNF3,ABCD2,MARCH4,SYT13,OGT,PPFIA4,APC,ALS2,VAT1L,SLC7A14,ARNTL,MARCH3,ATM,STX16,N4BP2L1,ADGRB2,DNAJC27-AS1,ARHGEF7,NAE1,SCAPER,BTRC,CACNA1D,DIRAS1,CALM1,KALRN,PRC1,SCARB1,LRBA,DCLK1,TIGD7,CNOT8,KMT2C,CLCN4,FAM19A5,NIPBL,RAB26,ARHGEF6,IQCK,AKAP6,BTF3L4,LETMD1,SLC4A8,ABI3BP,TOGARAM2,SEC24C,CSNK1G3,ATRNL1,DZIP3,APPL1,PLCXD3,NRSN1,GPSM1,EDRF1,CYBB,GAPVD1,DCAF8,HEPH,CNIH3,RHOBTB1,SNAP91,DMD,ECM2,E2F5,AASDH,FAM135B,EDNRA,EDNRB,FRY,EFNB3,GPR61,GOLGA7,EIF4G2,TENM1,ELAVL4,USPL1,EIF1,TUBD1,COQ7,RCAN2,LRRC17,ERBB2,CEP85L,ZNF549,CDKL3,F3,CLVS1,ABCA8,CORO2B,EFEMP1,DLC1,CHST15,POLK,SUCO,SYNCRIP,FLT1,NELFCD,TMEM107,RASL10A,ERGIC3,KHDRBS3,DACH2,B3GAT1,DOT1L,OGA,GABRA2,DENND2A,HBS1L,FAM120B,ZMYND11,NKX6-2,GBX2,GFRA2,RAB30,MSL3,ZNF638,HTATSF1,INSM2,LUZP2,GPD2,GPM6A,LILRA1,EML4,GRIA1,NR3C1,KIF3A,BVES,MAEL,HAS2,AGBL5,CELF5,LRRC25,RBPJ,IGSF1,LIX1,ZNF678,ITGAV,KCNA4,KCND1,LAMP2,LIFR,LMO1,VWA5A,HECTD2,SMAD1,GPR155,MAOB,MEIS1,AFF1,MRPL42,PTOV1,MDGA1,HS6ST3,MYO7A,MYO9A,NCAM2,NEUROD1,NPTX1,SLC11A2,NRDC,NTRK2,GPR88,CHAMP1,P2RX7,KCNK10,ETFRF1,PDGFRA,PDYN,GDAP1L1,CDIP1,ING3,SPATA6,POLR2F,POU3F2,PPP2R5C,PRKAB2,PRKACB,GRAMD1C,MASP1,BCAS3,VPS13C,SNRK,TMEM260,PTPRE,ACSS3,ATG16L1,RADX,BSDC1,RDX,TRIM68,ERI2,RFX4,SEC61A2,RIC8B,PBRM1,LGI2,RAVER2,CCDC102B,ACER3,ABCA11P,HUNK,CLIP1,ZNF568,SCN4B,SCN8A,TNFRSF19,MRAS,SGK1,CPEB3,DOCK10,CTXN2,NUBPL,PAAF1,ZNF365,CCDC88A,TMEM132D,ANKRD36,MAPKBP1,SNCA,UNC80,DOP1A,MYT1L,SOX5,KIF21B,ENKUR,CAND2,ZC3H13,KIF1B,RBM26,C11orf87,CLSTN2,POGZ,ADHFE1,KANK1,SYT11,SYNE2,TAC1,TBX15,NEU4,ZEB1,TRIM2,WASHC4,CLASP1,ARHGEF12,TEX15,TEK,AP4E1,HHIP,SLC44A1,TLL2,TMPO,TPM3,PRMT8,CADM1,UBE2H,SLAIN1,VAV2,MEAF6,RICTOR,SLC13A3,XPO1,ZNF24,TRIM9,FMN2,ANKS1B,PRDM2,GDPD5,SIGLEC10,WIPF2" MicroRNA hsa-miR-1274a:mirSVR_lowEffct hsa-miR-1274a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.00E-101 2.25E-97 2.49E-100 2.29E-99 293 1364 "KDM5D,GPRIN1,CSMD3,ADCY6,ADD1,PLEKHH1,ADORA2A,KIAA1211,NLGN4X,AK2,ZNF578,ALAD,KIF6,OGT,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,APC,DGKZ,GPAM,PHYHD1,PPFIA3,USP37,SHTN1,IGDCC4,BRINP2,DYNLL1,DST,SGCE,NIPA1,IL33,CACNA1B,CABP7,KALRN,BRSK2,CERS5,MTMR7,CDK11B,ARHGEF2,LARGE1,SOCS6,ASIC3,NRXN3,TPP1,DNAJB5,CNGA3,SUMF2,AKAP5,MFSD4A,SLC32A1,NCOR2,GDA,AATK,SNCAIP,CSF1R,ARHGEF10,CFAP61,ECE2,ARHGAP32,EARS2,RIMS3,AIF1L,DNAJC6,C8orf34,ZEB2,SV2B,SV2A,SRGAP3,NTM,RABGAP1L,EXOG,DOCK2,DMTF1,ACOT8,FARSB,ABCC5,ABCC9,SNX29,ANKRD46,CNNM1,SEMA3D,TMTC1,YAF2,SORBS3,CERCAM,ELAVL4,ELN,TMEM35A,EMX2,EPHA5,MRPL10,ADGRV1,REEP2,CLVS1,WAC,CHST15,PPP1R1B,FER,FGF1,IP6K2,EFCAB2,TACC2,SORBS1,POMT1,UFM1,PDLIM5,RASL10A,CELF1,STAU2,DOT1L,NRG3,GABRA5,ZMYND11,ERAP1,DISC1,WASF3,GFER,PCDH17,GLS,POLL,CNDP1,GPD2,STON1,LPAR4,GPR26,GRIA4,PLCD4,GRIK1,CLASRP,FAM19A2,MFSD2A,RABL2A,ADAMTS6,SLC2A6,WIF1,DDX19B,LINC01102,SYNPO,HNF4G,HNRNPK,CPT1C,LRRC75A,C2orf72,IL11RA,SLC6A17,SLC35G1,KCNA1,KCNJ10,KCNK1,KCNK3,KIF5C,CYP27C1,MAN2A2,CHIC1,XRRA1,SCG3,LYRM9,NAP1L1,ALDH1L2,NNAT,CNOT4,HCN1,OCRL,OGDH,ZNF713,ZDHHC22,PC,CDK18,PDGFRA,BEST3,CDK14,ZNF655,ZFYVE21,PLCB2,C11orf49,POLR2F,POU3F2,MED1,PPP3CB,PRKCZ,EPDR1,GRAMD1C,HYDIN,PROX1,CNNM2,VPS13C,SLC22A23,CYBC1,SIDT1,CNTLN,PTCH1,PTPRB,PTPRD,PTPRE,FAM120C,RAD51D,SH3TC2,BSDC1,RGS12,ARHGEF10L,MRPS18A,RPRD1A,MRAP2,RPE65,ZC3H14,PAQR6,ZNF568,AMER2,ATXN2,SCN3A,ZNF821,COPZ1,ITSN1,SH3GL2,NTNG1,AMBRA1,ANKRD6,ABLIM3,ZNF365,PPP4R3A,KANSL3,LRRC55,SLC11A1,SLC15A2,ATF7IP,CPEB4,IFT122,RIMS1,KIF13A,UNC80,SON,SOX1,MYT1L,SOX10,ZSWIM8,NMNAT2,CLUAP1,ERC1,SPTB,ZBTB43,TSPYL2,NPAS3,TAB2,CAMTA2,SMOC1,ERBIN,ELOVL4,SEPT8,CEP68,PHLDB1,KANK1,STXBP1,GSE1,FGD4,PRRC2C,SYNE2,ARHGEF9,VPS13A,MCF2L,EXOC7,IQCE,TBL1X,TCF7,RPGRIP1L,AKNA,FRYL,SIK3,CRB1,LEFTY2,GPR161,SEZ6L,METTL3,SMUG1,STXBP4,TRPC3,FNDC5,UBE3A,BEST1,CFAP298,ZBTB14,FMN2,ZNF154,TMEM237,FSTL5,UPF3A,EMSY,GDPD5,LINC02210,PCDH15,UBE3B,FAM219B,RNF170,SLC4A10" MicroRNA hsa-miR-550*:mirSVR_lowEffct hsa-miR-550*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.64E-101 3.17E-97 3.50E-100 3.23E-99 279 1244 "NCKAP5,CSMD2,CSMD3,GALNT16,ADD3,PLEKHH1,NLGN4X,AP2A2,LRRC7,SEMA6A,ALCAM,AMPH,ANK1,CDC14B,TMEFF1,ARNTL,STK33,NUMB,DDX3Y,ATP1B3,SLC2A11,ADAM23,LINC00847,BBS2,MPDZ,HCN2,BMP7,DST,SYNJ1,ARHGEF7,CASTOR3,CACNA1G,OSGIN2,CACNA1E,CACNB2,KALRN,PTBP2,CAST,METTL6,SYNGR3,DGKI,LRRFIP1,LOC730101,MAGI1,CCPG1,SRSF11,CHRNA4,EPS15L1,QKI,MAP4K4,FAM149A,BTF3L4,COX4I1,AHCTF1,FAM171B,RBM39,GDA,TRIM69,CS,FEZ1,VAC14-AS1,PHACTR3,PUM1,EDRF1,DNAL1,ARMCX4,TIAM2,GUCD1,CHRDL1,DLX1,DMD,USP3,CPEB2,ABI1,ECM2,FARSB,EBF1,EDNRB,CNNM1,EFNA3,EIF5,IRAK4,ELAVL2,RGS17,TUBD1,STX2,SRRM1,EPS8,ZNF549,F3,ARMCX1,CLVS1,EFEMP1,ST3GAL6,PRMT5,TESK2,FER,GTF2IRD2,FGF12,FGF13,CAP2,C2orf88,EFCAB2,WDR83,APOPT1,FAM49B,NSG2,NSG1,ABLIM2,ZNF512,GABRB1,GABRG1,GAD1,GALC,TMEM8B,KIAA1841,DNER,MSTN,COPS8,DBF4,CBX1,GNAS,ADGRA3,GRIA1,GRIA2,GRM7,GRM8,CIT,GUCY1A1,GUCY1B1,IRAK3,KLF12,HMGB1,SCRG1,HNRNPK,HSD17B1,SHISA6,HSP90AA1,IDH3A,DOCK7,PLD5,USP54,IL6ST,ZNF385B,ITGAM,KCNA4,KCNK1,LAMP2,LIFR,VWA5A,ARHGAP12,CLEC18A,MEIS2,POC1B,AFF1,MOBP,MOG,CCDC80,DDX25,NCAM1,ZC3H12B,RCOR2,NF1,ALDH1L2,NOVA1,NTRK2,IGSF11,ODF2,OXTR,PCDH9,PCMT1,PCSK1,PCSK5,PDE2A,FAM98B,ZDHHC8,ANLN,FAM216A,JAKMIP1,HMGCLL1,STRN3,PRRX1,IRX1,PPM1B,PPP3CB,RASGEF1B,PRKCB,PRKCZ,PSMD13,PTN,TMEM260,PTX3,CEP97,ACSS3,FAT4,GTDC1,NUDT11,ZFHX4,CCDC82,CARF,GSTCD,RORB,CCDC102B,WLS,RTKN,KCNIP2,SEMA6D,ELMOD1,SGK1,SH3GL3,ASAP3,FBXO11,SEC31A,RAB3GAP1,SLC12A2,TMEM132D,ZKSCAN3,LMBRD1,FAM126B,SON,KIF21B,BEX1,ATP10B,PBLD,SSTR2,NKAIN2,ELOVL4,KANK1,SULF2,SYNE2,TAC1,DDHD2,TAF9,UNC5D,EHBP1,TCF4,KIAA0930,TCF12,RALYL,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,TEK,SLC44A1,THRA,TLR4,ZFP91,TPM1,NPL,TPM3,ZNF384,ZNF346,TRPC1,RFTN2,CADM1,EIF4ENIF1,FLRT2,PLEKHH2,WRN,CFAP298,PCDH20,MICU3,LYPD6,CELF4,REEP1,PRTFDC1,RNF103,HPS4,PCDH15,FIP1L1,FBXO36,JMJD1C,RNF170,NETO1" MicroRNA hsa-miR-495:PITA hsa-miR-495:PITA_TOP PITA 5.91E-101 3.32E-97 3.67E-100 3.38E-99 215 740 "KDM5D,ERMN,MTA3,GPR158,TAOK1,ALCAM,ARHGAP20,TRMT9B,AMPH,DPP10,APP,TMEFF1,ARHGAP5,ZBTB10,NCOA1,DDX3Y,EIF4G3,ATP2A2,ATP2B2,ADGRB3,ST3GAL5,FUBP1,JAZF1,LDLRAD4,BTRC,CACNA2D1,CAMK2A,CAMK2G,CANX,SYT6,CAST,RUNX1T1,CLDN10,CERS5,CBFA2T2,SEPT7,LARGE1,MAGI1,SRSF11,CHN2,LHX2,KMT2C,NRXN3,CNR1,ARMC8,BTF3L4,SLC35F1,CLOCK,CREB5,CSNK1E,RIMS4,PLCXD3,CTNND2,ST18,USP6NL,DOCK4,LONRF1,KCTD8,PABPC5,BRINP1,DBT,MYEF2,MFAP3L,HP1BP3,RHOBTB1,SPOCK3,DLG3,ABI1,DYRK1A,E2F5,KLHL5,MBNL2,TENM1,RGS17,EPB41L2,ETV1,KATNAL1,ACSL4,ZIC4,DLC1,ATP8A1,GORAB,PRKAG2,SUCO,FOXG1,FOXO3,AFF2,CELF1,STAG2,DNER,PCDH17,TNRC6A,FERMT2,ADGRA3,GPD1,GPM6A,GPR22,EML4,GRM7,FAM19A2,ADAMTS6,ARHGAP19,KLF12,BACH2,HLF,HNF4G,HNRNPK,NEGR1,HSF2,IGF1,C5orf24,SMAD1,MARK1,LDLRAD3,SESN3,NEXMIF,NAP1L1,NFIA,PCDH9,PDE4D,PLCL1,HMGCLL1,LRP12,EPB41L4B,MED1,MINDY2,PPP2R2C,PPP3CA,MAPK10,PTCH1,PTK2,PTPN13,PTPRD,PTPRE,PTPRZ1,NKAIN1,ARID4A,KHDRBS2,RET,PRRT2,GTDC1,PBRM1,ZFHX4,RORB,SNX22,FBXW7,MCMBP,SALL1,SATB1,SCN2A,SCN3A,SCN8A,SOX6,SFPQ,SGK1,CPEB3,CHD9,FBXO11,R3HDM2,SLC8A1,TRIM67,SPHKAP,SNAP25,FAM126B,FAM219A,WDTC1,MYT1L,SOX5,ZCCHC24,SP4,CLASP2,POGZ,SSTR1,LRRC4,MPRIP,GSE1,NSFL1C,RHBDL3,ANKRD12,CAMTA1,CAMSAP2,FAM208A,TCF4,TCF7,RPGRIP1L,WASHC4,SIRT1,HEY1,TJP1,TMOD1,R3HDM1,RBFOX2,RASD2,TPM3,TSN,LRTM2,CADM1,RPRM,FAM155A,UBE3A,VAV2,ZBTB14,ZIC3,ZFAND5,WNK1,EMSY,FIP1L1,SLC17A6,MVB12B,GOPC,RTN4,KAT6A,ACTR3B,ST8SIA2,CPNE4" MicroRNA hsa-miR-449b*:mirSVR_highEffct hsa-miR-449b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.48E-101 5.32E-97 5.88E-100 5.41E-99 229 844 "KCNH8,ACTN1,KDM5D,ERMN,AP2A2,WDR35,HFM1,FAM135A,AMPD3,OGT,MAP4K3,SMIM29,PPFIA1,APC,UPRT,ALS2,VAT1L,TMEFF1,CADPS,DDX3Y,TMEM108,KIF1A,TTLL9,CACNA1B,CACNA1E,CACNG1,LURAP1,CALB1,PTBP2,CAMK2A,PRC1,CLDN10,MTMR7,TMEM257,LRBA,CDH8,LGI1,DLGAP1,RCBTB2,SRSF11,SYNPR,RAB28,PPT2,TMEM59L,TJP2,SRP14-AS1,TMEM155,ARMC8,LETMD1,SLC4A7,SLC4A8,ZFP28,CRMP1,SEC24C,CTNND1,RIMS2,DCAF4,CYBB,HDAC9,ARHGAP24,EARS2,ZEB2,C2CD2L,DDX46,DLG4,ECM2,ABCC9,GOLT1B,E2F5,ANKRD46,PHF20L1,KMT5B,COPS4,STARD3NL,EIF1,EN2,ENO2,VPS13B,LRRC17,EPHA5,CDHR1,RTN3,ST3GAL6,KIAA1109,FGF13,MEX3B,CAP2,DCTN2,TRMO,NSG2,ST6GALNAC3,ZMYND11,GALC,ARPP21,GAP43,DNER,WASHC2A,TCERG1,TOX3,PCDH11X,MAP7D2,STON1,EML4,CNTRL,RAPGEF4,GRIK2,SERP2,GRM2,RABL2A,PSIP1,IRAK3,IGFBPL1,SHISA6,MSL1,RBPJ,ZNF385B,KCNK2,KIT,LAMP2,PAXBP1,MBD1,TM6SF1,MEF2C,SCAMP5,BLOC1S2,NAP1L2,FXYD6,P2RY13,NCAM1,NCAM2,NDP,NEUROD1,NKX2-2,GPR137C,PDE4B,PDGFRA,PDPK1,OLA1,SERPINI1,CAMKV,PRIMPOL,LRP12,PRRX1,SEPT4,MINDY2,PPM1B,PPP2R5C,PPP3CB,PPP3CC,PRKACB,PKIA,PRKCZ,MAPK9,HYDIN,RELN,MDGA2,PSMD13,PIGG,PLPPR1,PTHLH,SPDL1,TMEM260,STK32A,C1orf109,TMEM255A,RBBP6,HKR1,RFX5,ZDHHC4,RGS7,PBRM1,RORB,RPE65,SPIN3,LGR4,KCNIP1,CLIP1,SEMA6D,SCN8A,SUPT20H,ZFP30,KIF21A,ITSN1,SH3GL3,FERMT1,KIF16B,HKDC1,SLITRK3,NUBPL,KANSL3,SORCS3,CDK5RAP2,SNCA,SNRPN,MYO16,KDM4B,SON,KDM3A,SPP1,ZC3H13,SRPK2,POGZ,MAPK8IP3,DIP2A,NUDT10,ADGRL3,KLHL4,SIN3B,SATB2,TCF7L2,ZEB1,WDR7,SIRT1,ASXL3,BHLHB9,TRIO,PLEKHH2,CCDC136,ZNF711,ZNF17,LYPD6,ZBTB16,PLPPR5,ZXDA,LRP8,PARP6,PCDH15,RNF170,SLC4A10" MicroRNA hsa-miR-504:mirSVR_lowEffct hsa-miR-504:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.19E-100 6.67E-97 7.35E-100 6.77E-99 301 1441 "EMILIN3,SLC25A25,GALNT16,ADCY6,ADD2,ADD3,SLC12A5,ADRA1D,RTL9,TXNDC16,C1QTNF3,LRRC7,SEMA6A,CARNS1,SYT13,MRTFA,DOC2A,ZFAT,ANK3,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,APAF1,APOC2,AMER3,BCAS1,SFMBT2,SPTBN4,CDK13,TMEM108,DPY19L3,DOCK11,ADAM23,ADAM15,SNAI3-AS1,LINC00847,SGCE,OSGIN2,CFAP410,CACNB2,CALM1,CANX,CBS,SHISA7,USP2,CD86,TMEM257,LRRFIP1,CDH18,IGFN1,LSMEM2,NMT2,ABCG2,CNGA3,IGLON5,PICK1,CNTFR,AKAP7,RCHY1,IFFO1,SMARCAL1,SEC31B,NCOR2,ABCG1,SNCAIP,ATRNL1,VAC14-AS1,ERC2,CFAP61,EDRF1,TBC1D5,DAPK1,HP1BP3,COPS7A,ZC3H11A,WDR20,RAB39B,DNAH9,SLC29A4,DNM2,DPH1,FAM57B,GNE,DNAJB6,DYRK1A,ABCC5,ABCC9,KRBA2,EBF1,FAM135B,PHC2,RASGRP1,SIDT2,YAF2,PHF20L1,SUGP2,RASA4,PLEKHA1,C3orf18,EMX2,VPS13B,EPB41,EPB41L1,SEZ6,EPHB1,ETV1,VPS26C,DNAJC27,TLR7,RPS6KC1,ZIC4,FCGRT,PPP1R1B,FGFR1,PRKAG2,HPCAL4,FLT1,NOP56,EFCAB2,ARFGAP2,GPR153,AP4B1,STAG2,GABRB3,GHDC,GAP43,MTHFD2,SEPT9,INPP5K,IGSF5,GCNT2,GGT7,RND1,SPIN1,HTATSF1,KCNMB4,GPT2,PRRC2B,LILRB4,TMEM121B,GRIK1,GRIK4,ZNF496,BTN2A1,CLASRP,GUCY1A2,MUM1,PTGDR2,BACH2,VSIG4,ELOVL5,ZNF491,C9orf129,HTR5A,ICA1,IRF8,LINC00667,LIX1,ITIH2,KCNK1,KIF5A,HECTD2,ASPRV1,CLEC18A,MAN2A2,ZFYVE27,MAP4,MBP,LDLRAD3,PPM1L,MOBP,MXI1,NFIX,NHLH1,NNAT,SLC11A2,HCN1,NUCB2,PIRT,PDPK1,GDAP1L1,ZNF655,A2ML1,CCSER2,SMIM7,CDIP1,LRP12,SCHIP1,TNPO2,PTPA,VSTM2L,HYDIN,PRPH,CNNM2,PSMD13,PTAFR,MTMR10,ZSCAN32,PTPRE,TTC13,PLEKHB2,RALGDS,ZDHHC14,RFX2,RGS12,RLBP1,KLHL11,CCDC82,EXD2,PNMA8A,KIRREL1,SNX22,RPL15,ADAL,EMID1,ST6GALNAC6,ATAT1,DGLUCY,ATXN2,HOGA1,SCN2B,TNFRSF19,SMPD3,SOX6,MRAS,TRA2B,ITSN1,SH3GL2,FERMT1,NTNG1,HKDC1,BCAN,ANKRD6,SLC14A1,NAPB,SMARCA4,IGSF9B,ANKRD36,RIMS1,SNCA,MBD5,FAM126B,SON,WDTC1,FNBP1,SPP1,NPAS3,SPART,C11orf87,POGZ,SSTR2,ZC4H2,ST5,NCDN,SEPT8,ARHGEF9,SYN2,C12orf76,MTCL1,SEMA4A,PDLIM2,SMG6,ACSL6,DMXL2,TCF7,TMEM151B,SIK3,RNF216P1,VWCE,AP4E1,AKTIP,FBXL16,ZFP91,LRRC8A,DAAM2,CSMD1,PRMT8,TRIO,STXBP4,FNDC5,UGT8,FLRT2,PLEKHH2,MEAF6,VLDLR,CLIP2,NSD2,CLDND1,GUSBP1,ZIC3,CRB2,LYPD6,ZFAND5,RGMA,CSDE1,TMEM178A,PLSCR4,ZNF248,SPATA13,SENP7,JPH3" MicroRNA hsa-miR-769-3p:mirSVR_lowEffct hsa-miR-769-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.23E-100 6.93E-97 7.63E-100 7.03E-99 292 1361 "ABAT,ABCF1,NCKAP5,NBAT1,ADCY6,CCDC85A,GALNT13,SORCS1,ERMN,ADORA1,OSBPL1A,ALCAM,AMPD2,ZFAT,SUGT1P4-STRA6LP-CCDC180,APLP1,CACHD1,TNRC6C,AQP6,ZBTB10,ASTN1,NOL4,KSR1,LINC00906,KALRN,SPAG9,SHISA7,LDB2,USP6,P2RX6,CD86,MAGI1,CDO1,ZBED5,DLGAP3,NRXN3,DNAJB5,HECTD1,CNN3,ARMC8,COL9A2,ABI3BP,SLC35F1,CLOCK,CREM,RBM39,CLIP3,CSF2RA,NCAN,GREB1,CFAP61,DCAF4,CCDC144A,BOC,RIPOR2,CENPL,TM9SF4,LIN54,IST1,TOMM20,DNAJC6,MYEF2,MAGI2,SRGAP3,NTM,SGSM2,KIF19,CHRDL1,DLG2,DYNC1I1,TOM1,DUSP9,MAMLD1,ABCC5,WDPCP,EDNRB,CELSR3,FAM13A,EGFR,AASS,CERCAM,SPEG,RASL12,GMPR2,PTK2B,MAD2L2,PRKAG2,HPCAL4,SYNCRIP,FOXO3,ANKFY1,NOP56,NELFCD,CELF1,B3GAT1,ABLIM2,FYB1,MEGF11,GABRB3,BRPF3,DISC1,STARD10,MALT1,ZNF638,LNX1,WDFY3-AS2,PRUNE2,FUT10,LILRA2,GPR17,STON1,GRM2,PRDM5,GRM5,GSTM5,PACSIN2,DHX35,FAM95B1,SOWAHA,TJAP1,SCRT2,DIPK1A,NME9,OLFM3,KCNB1,KCNJ10,KCNK2,STMN1,PAXBP1,SYTL4,NCOA7,SMAD1,GPR155,C1orf194,MATN3,MEF2C,MID1,CD200,MPP2,ERICH3,ADAM22,ZNF92,ZNF862,FXYD6,NCAM1,NHLH1,HCN1,OPHN1,SNTG1,DPY19L2P2,CDK18,PDE4D,PDGFRA,PDYN,GDAP1L1,PKM,NLE1,SLC25A23,HMGCLL1,MAPKAP1,CDIP1,RC3H2,LRP12,PPARA,PRKAB2,MAPK4,CNNM2,BCAS3,WDR25,PTK2,PTPRB,OCIAD1,PTPRH,PEX2,TUG1,TMEM231,RALGDS,GAL3ST4,CRTAC1,TRIM68,GTDC1,RFX4,RGS7,KLHL11,RERGL,DCUN1D2,SETD5,CARF,NEK11,ZC3H14,ATP8B4,GLDN,SYNDIG1,MEG3,HUNK,ATAT1,STX1B,SEMA6D,SCN2A,LRRTM4,DOCK10,R3HDM2,BCAN,NLGN1,ST3GAL3,SMTN,SLC6A1,KDM4D,SLC8A3,SLC12A4,BTBD7,ATF7IP,SPHKAP,ZFP1,ANKRD36,RIMS1,SNCB,MBD5,USP33,DOP1A,ZSWIM8,SP4,CLUAP1,PEG10,RBM26,LARP4,LRRC4,NCDN,STAU1,ELOVL4,SULF2,NSFL1C,SYT11,FGD4,JMJD6,SYN1,ANKRD28,PJA1,CAMTA1,MLST8,VWA3A,SIN3B,KIAA0930,TRIM2,RPGRIP1L,CLASP1,WDR7,SYNE1,AHCYL2,RNF216P1,TEK,DICER1,CRB1,ENHO,FAM124A,TPM1,RGMB,METTL3,ELP5,STXBP4,OSBP2,BCL2L13,MEAF6,CCDC14,BEST1,NSD2,XPO1,SF1,ZIC3,ZNF711,ELFN1,FMN2,ZBTB16,TMEM237,DPYSL5,EMSY,PRDM2,GDPD5,XKR7,HPS4,PCDH15,FIP1L1,CAB39L,PLSCR4,DNAH10,DOCK8,UBE3B,HNRNPA3,ZNF248,VANGL2,NETO2,NETO1" MicroRNA hsa-miR-934:mirSVR_lowEffct hsa-miR-934:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.37E-100 7.70E-97 8.47E-100 7.80E-99 249 1000 "FAM43B,CSMD3,RNF157,ADD1,PLEKHH1,ESYT2,ADRA1D,SLC44A5,ALCAM,LRCH2,CCDC146,PKP4,SHTN1,TMEFF1,ARNTL,ASTN1,SLC2A11,DOCK11,AZGP1,BACH1,DCAF5,CFLAR,DST,FUBP1,GYG2,PTBP2,DCLK1,ZMYM4,CHGB,CHN2,CASC2,SYNPR,B4GALT6,NDST3,NRXN3,QKI,BTF3L4,ZNF521,MFSD4A,C2CD2,HAPLN1,ARHGEF10,ATRNL1,SIPA1L1,PNPLA8,PUM1,CX3CR1,BOC,EARS2,ZNF337,MATR3,DGKB,TMEM170A,DBI,ARMCX4,BLOC1S6,SPOCK3,MTX3,WDR20,PDCD6IP,HIPK3,SEMA3D,FRY,RBM12,CELSR3,MBNL2,KMT5B,PLEKHA1,PCOLCE2,OLIG2,ANKRD13B,DENND4A,EYA1,CLVS1,FABP7,SCML2,ATP8A1,TOMM40L,FDFT1,FGF14,FGFR1,SUCO,UBE2E3,FOXO3,WDR83,SMC2,FAM49B,ZNF512,OGA,GABRA1,GAD2,HBS1L,DISC1,LRRC37A6P,DNER,MYOZ2,SESN1,GFER,GK,DBF4,SPIN1,RAB30,GLRB,TOX3,AIFM3,POLL,LILRB4,PCLO,RAPGEF4,GRB10,RNFT2,IRAK3,PADI2,FRMD5,FRMD3,HNF4G,NEGR1,AGFG1,HSP90AA1,IRF8,MSL1,FAM95B1,RBPJ,BRINP3,LRRTM3,NME9,JAK2,KCNA1,KCNC2,KCNJ9,KCNQ3,KIF5C,IPO5,KTN1,PIK3AP1,MAP6,MARK3,MEIS1,AFF1,ERICH3,ADAM22,MSR1,ZNF92,MTTP,MX1,NCAM1,NEUROD1,NTRK2,NUCB2,CHAMP1,KCNK10,GLIPR1L2,SNTG1,PCDH9,PCSK5,PFKFB2,ABCB1,XRN1,GPSM2,HMGCLL1,MTRF1L,PSAT1,FAT3,MED1,PPP2R5C,RASGEF1B,PRKCZ,MAPK7,DIRAS2,SIDT1,BDNF-AS,PTN,PTPRE,FAM120C,PTPRZ1,STRC,ACSS3,ZDHHC14,ZYG11B,FIGN,RGS12,ZFHX4,GSTCD,CCDC102B,NEK11,GLDN,MAP6D1,PAQR6,ABCA11P,RTN1,NCBP3,SCN7A,ZFP2,MRAS,SGK1,ZFP30,KIF16B,NLGN1,NUBPL,EPN2,SLC8A3,SLC12A2,EFHD1,BTBD7,PALLD,FAM126B,UNC80,DOP1A,ENKUR,EMC1,KDM4C,RBM26,SRPK2,SAMSN1,TTBK2,NUDT10,POPDC3,CAMTA1,CAMSAP2,ADGRL3,VWA3A,EHBP1,VWC2,ZFP90,ZEB1,SIRT1,ITGB3BP,AKTIP,TJP1,ERCC6L2,TRIO,ANO5,CLHC1,TMEFF2,PITPNB,NSD2,LYPD6,ZBTB16,ZFAND5,WNK1,PMEPA1,CADM2,PRDM2,EVI5,NAV2,TIGD6,NETO1,SOCS4,FAM198A" MicroRNA hsa-miR-3117:mirSVR_lowEffct hsa-miR-3117:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-100 9.77E-97 1.07E-99 9.89E-99 252 1025 "ACTN2,SLC25A25,CSMD3,TMCC3,ADD2,SNX32,PCDH19,RTL9,OSBPL1A,ALCAM,SRPX,ARHGAP20,SYT13,ZFAT,CDC42BPA,MAP4K3,MYH7B,PPP4R4,CADPS,ASPH,ZBTB10,SLC4A4,ATP2A2,ATP2B1,NOL4,BACH1,SYNJ2,ARHGEF7,CACNA1G,CACNA1B,CACNA1D,CACNB4,CACNG1,SYT6,P2RX6,DCLK1,MAGI1,CCPG1,CLGN,NPIPA1,PLAA,PPT2,TPP1,RAB26,CNR1,CNTN1,COL9A2,ACBD5,CREM,HAPLN1,ANKRD44,CLIP3,PNPLA8,BOC,HDAC9,TOX,ZNF337,LONRF1,IST1,JAKMIP2,C8orf34,DGCR5,CEP170,KLHL3,WDR20,USP3,SLC25A18,AASDH,KLHL5,RBM12,EGFR,PLEKHA1,ELAVL3,DCTN4,SEZ6,NCALD,RASL12,F8,FABP7,ZSCAN30,ZNF589,FGR,SUCO,MEX3B,PCYOX1,SYNCRIP,FOXO3,SGIP1,TMEM175,KHDRBS3,PNMA2,B3GAT1,STAG2,DKK3,MEGF10,GABRA2,ZNF44,CHL1,HBS1L,ARPP21,GATM,GFER,BRD8,ATF7,MCHR1,PCLO,ADAMTS13,NR3C1,GRM2,FAM19A2,RNF165,ADAMTS6,LINC01102,BACH2,MIER3,HMGCL,HNRNPK,ZDHHC15,SHISAL1,LRRC25,DOCK7,IL11RA,CREG2,KIF5A,KIFC3,L1CAM,LIFR,MBP,MITF,ERICH3,MSR1,MXI1,MYO7A,NDUFA5,ALDH1L2,NOVA1,SMIM11A,GPR88,OPA1,OPHN1,PBX1,PCMT1,PCSK5,PDE3B,ENPP2,PFKFB2,PIK3R1,CCSER2,FTO,MTRF1L,PURG,RC3H2,PPM1B,PRKAB2,GRAMD1C,MASP1,ZSCAN32,OCIAD1,PTPRH,FAM120C,RAB5B,RBBP6,KHDRBS2,MSANTD2,ZMAT4,ZDHHC4,RGS4,RNASEL,ALG9,ARMH4,KIAA0895L,ACER3,KCNIP3,FAM19A1,SELL,NLGN4Y,ZFP30,SH3GL3,FERMT1,FBXO11,SEC31A,ST8SIA1,SLA,PEX26,DHX30,FAM214B,ZNF430,ARHGEF40,CCDC88A,SLC12A2,BTBD7,RIMS1,SNCA,MBD5,SNRPN,TMCC1,USP33,PDZD2,FNBP1,SP4,UNC5B,KIF1B,ZBTB43,NPAS3,ATP10B,SMOC1,ZSCAN29,SEPT8,CEP68,GSE1,NSFL1C,COBL,FAM208A,UNC5D,TBCEL,ANO4,TPCN2,TRIM2,RPGRIP1L,PUM2,TEK,DICER1,CRB1,TGFBR3,GZF1,ACTR6,BHLHB9,HEY2,BEX4,RIMBP2,PIK3R5,RBFOX2,TPD52L2,TPM1,CHST5,TTTY15,CADM1,MTCH1,ATP6V0E2,MKRN3,LYPD6,ZFAND5,INTS3,SLC38A1,RNF103,SCG2,FIP1L1,FAM47E,ST7,CBLN2,SOCS4,SLC4A10" MicroRNA hsa-miR-2110:mirSVR_highEffct hsa-miR-2110:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-100 1.32E-96 1.45E-99 1.33E-98 263 1116 "RALGAPA1,ASIC2,ASIC1,AS3MT,GPRIN1,PLEKHH1,GRAMD1B,ADORA3,KIDINS220,HECW2,CASKIN1,WDR35,C1QTNF3,BCAR3,ZNF687,AMPD3,LRCH2,PHF12,PHYHD1,PPFIA3,LGR5,SEMA4G,RASL11B,STX16,ATP6V1G2,TTLL9,RGS11,CFLAR,BMPR1B,DST,FUBP1,MTMR2,C5,CACNA1D,PTBP2,TRIM41,VXN,SPAG9,ARHGEF25,CBR1,USP2,MTMR7,CD38,C1orf52,CDC42,ZMYM4,LOC730101,CASC2,CNOT8,COG1,TPP1,CLTC,TJP2,DNAJB5,ARHGEF6,COL4A5,SUMF2,ZFP28,HAPLN1,RNF14,HINFP,GDA,CLIP3,SNCAIP,SUSD5,PHF14,CFAP61,ST18,CYBB,RIPOR2,CENPL,AIF1L,YTHDC1,CNIH3,CEP170,SACS,SPOCK3,SV2A,G3BP2,DLG4,OLIG1,PDCD6IP,RCAN1,DNM1L,PHC2,FCF1,PHF20L1,C3orf18,TMEM35A,C8orf37,DCTN4,ENO2,EPB41L1,ANKRD13B,MRPL37,SIRPB1,RPS6KC1,ACSL4,TAOK3,CORO2B,FGF14,FGFR1,FOXF2,PCYOX1,FLT1,NOP56,HVCN1,STAU2,ZNF512,DKK3,GABBR1,GALNT15,ARPP21,GALR1,TMEM8B,IGSF5,SRCAP,ARFIP1,PPARGC1A,ZNF276,GLS,TNRC6A,INSM2,LUZP2,CNDP1,PCLO,GRIK1,GRIN2C,LINC01551,ADAMTS6,UBE2QL1,PADI2,HMGB1,ZDHHC15,LRRC75A,NKD1,IGSF1,LIX1,IL6ST,ZNF678,DIPK1A,SLC35G1,KCND3,KCNMA1,KHK,KIF5A,HECTD2,MAN2A2,MAOB,MAT2A,POC1B,CD200,ADAM22,PTOV1,SCG3,NF1,DNHD1,NUMA1,SETD4,TBC1D25,OGG1,OPHN1,BEST3,ZDHHC8,FAM218A,SMIM7,HMGCLL1,PURG,PRIMPOL,MAPKAP1,RC3H2,PILRA,PRKACB,CEP41,RAB39A,PRKCG,DIRAS2,DCHS2,MASP1,BCAS3,TMEM260,CASTOR1,PTPRG,PYGM,ZDHHC14,ZMAT4,RFX5,ZFHX4,CCDC82,SETD5,ROBO2,YY1AP1,MRAP2,STK32B,CNTNAP3,LGR4,KCNIP3,TRIM46,SFPQ,MRAS,COPZ1,ITSN1,SH3GL3,ASAP3,R3HDM2,NUBPL,SLA,RPH3A,BTBD3,RAB3GAP1,SLC9A5,SLC11A1,EFHD1,SLN,ANKRD36,MBD5,SNRPN,MYT1L,MYCBP2,TEX2,SPART,ATP10B,ZC4H2,NCDN,ELOVL4,ADHFE1,FGD4,SYN2,POPDC3,MMS19,PJA1,WDR7,ARHGAP9,SIK3,DICER1,CRB1,ITGB3BP,SLC44A1,ARL10,RIMBP2,TRO,ANKRD20A2,TTC3,CLHC1,USP1,WIPF1,CLDND1,ZFP37,KCNT2,SPHK2,CELF4,ANKS1B,DHX33,WNK1,PRDM8,PRDM10,PCDH15,FIP1L1,ADAMTSL3,RNF170,NETO1,SLC4A10,PRRT4" MicroRNA hsa-miR-4251:mirSVR_highEffct hsa-miR-4251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.58E-100 1.45E-96 1.59E-99 1.46E-98 291 1356 "NCKAP5,NDRG3,SLC44A5,INTS2,MTUS1,GPR158,OSBPL1A,OSBPL6,LRRC7,BIN1,UPRT,BCAS1,API5,USP37,SHROOM2,MIER1,TMEM263,ARHGAP5,ARNTL,MARCH3,NUMB,MTMR9,DOCK11,ADGRB2,ARHGEF7,BTK,GYG2,CACNA1G,CA8,CACNA1E,CACNB4,SLC25A14,RUNX1T1,TMEM257,NEURL1,DCLK1,ZMYM4,MAGI1,CHM,CASC2,B4GALT6,TPP1,C4orf33,HECTD1,NIPBL,CNN3,ARMC8,COL9A1,IGDCC3,CPS1,GDA,CS,SEC24C,ARHGEF10,CSNK1G3,PDE4DIP,NRSN1,ZSCAN23,EDRF1,CCDC144A,GPRASP1,FRMPD4,MAML1,DGKB,MYEF2,HP1BP3,FBXL5,MAGI2,NTM,DLG2,DMD,MAMLD1,E2F6,EDNRB,ANKRD46,HIPK3,SYT15,SIDT2,PHF20L1,APH1A,EGR3,GOLGA7,STARD3NL,DCTN4,EPB41L2,EPHA5,CDHR1,ETV1,RRAGB,FABP7,SCML2,FCGR1A,CEP78,FDFT1,FGF14,SEMA4D,ATP13A4,JKAMP,NBEA,SMC2,SPECC1,ZNF605,DACH2,MSANTD4,FYB1,FYN,GABRA1,GALNT15,GABRB3,FAM120B,B4GALNT1,NEU3,ALDH1L1,MSTN,ARFIP1,GGTA1P,TCERG1,DBF4,GLS,TOX3,ZNF638,KDM2B,GPM6A,EML4,DIDO1,GRIA4,RFFL,GRM3,PRDM5,GRM5,RABL2A,TLX1,SHISA6,HTR2A,ZNF181,C5orf24,RBPJ,DOCK7,LRRTM3,ITGAM,SLC35G1,KCNH2,KCNJ10,KCNJ16,TTYH2,NCOA7,PACRG,CLEC18A,MARK1,MARK3,MAT2A,AQP11,MBD1,MEIS2,MIA2,NEK1,LRIT2,PCBP3,SLC11A2,IGSF11,P2RY1,GPR137C,SNTG1,PBX1,PCSK2,GNG2,BEST3,KCTD15,FAM216A,MAPKAP1,EXOSC10,NXPH1,DRAM2,MED1,PPP2R5E,MAPK9,SIDT1,PLPPR1,PTK2,PXK,TMEM260,ZSCAN32,PTPRE,CEP97,ACSS3,RAD17,NWD1,ARID4A,RADX,VEPH1,RDX,RLBP1,RPRD1A,ZFHX4,DCUN1D2,SETD5,CARF,ROBO2,RPE,SPIN3,ZC3H14,LRRK2,AP1AR,SCN3A,FAM19A1,SCN8A,SCP2,SLC30A10,FERMT1,NTNG1,SHC4,NLGN1,SEC31A,PPP4R3A,SLC6A1,SLC8A2,KBTBD4,SLC14A1,TET1,ZKSCAN3,ZNF667,RCOR3,ANKRD36,RBM34,KDM4B,DOP1A,BDP1,NMNAT2,SPP1,PEG10,RBM26,NPAS3,CLSTN2,SSTR2,LARP4,SYNE2,VPS13A,TAF6,CAMSAP2,MGRN1,SIN3B,DMXL2,ZFP90,TCF7,TCF7L2,ZEB1,TCF12,WASHC4,SYNE1,AKNA,CCDC173,PMS2CL,TGFBR3,MTMR14,ASXL3,HEY2,TMPO,C5orf64,CDK20,NPL,C9orf85,TPM4,SYNPO2,TRPS1,CA14,TUBB2A,CLHC1,TMEFF2,SGK3,PLPPR2,NSD2,ZIC3,MICU3,GPR158-AS1,NDRG4,ZNF142,REEP1,PLPPR5,SLC30A4,EMSY,CAB39L,PCBP4,WNK3,FZD3,HNRNPA3,ZNF248,RNF170,SSPN,NETO2,FAM198A,SENP7" MicroRNA hsa-miR-4317:mirSVR_lowEffct hsa-miR-4317:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.73E-100 1.53E-96 1.68E-99 1.55E-98 272 1192 "DPF1,ASPHD1,SYN3,NCKAP5,CSMD3,ADCY2,CCDC85A,SLC12A5,SORCS1,LRFN2,SLC24A4,ZNF608,HACE1,OSBPL1A,CC2D2A,AK2,ALK,AMPD2,PKP4,ANXA7,APAF1,ZFYVE28,LINC00173,ASPH,ALDH4A1,ATP6V0A1,AZGP1,MIR9-3HG,KSR1,CDK5R1,CALM1,KALRN,RUNX1T1,CBFA2T2,LRBA,REPS2,CDC42,MAGI1,CHRM1,NRXN3,CLCN4,CLTA,NIPBL,CNR1,AKAP6,ANKRD35,SLC4A8,TOGARAM2,MYRIP,RGS6,IPCEF1,SLITRK5,CTH,CCDC144A,BOC,DOCK4,KATNAL2,LIN54,SCRN1,CTIF,BRINP1,DBN1,ARMCX4,JAKMIP2,ZNF804A,ZEB2,MAGI2,FBXO25,PLPPR4,SACS,WDR20,FAM107B,DLG3,HS3ST2,CPEB2,AASDH,WDPCP,KMT5B,PLEKHA1,RABEPK,ERBB4,TLR7,ABCA8,SH3YL1,TBC1D16,ZIC4,FGFR1,FGFR3,BAIAP2,IP6K2,SYNCRIP,NOP56,NPTN,KBTBD12,ZMAT1,GABRA1,GABRG2,RAPGEF6,IP6K3,GAP43,ZNF559,DISC1,ATP8A2,ADAM28,GGTA1P,CRCP,ZNF638,GOLGB1,STON1,EML4,GPR37,PCLO,GRIK2,GRM3,GRM7,CIT,GUCY1B1,IRAK3,EID2B,RBPJ,SCIN,JAK2,SLC35G1,KCNJ3,KCNJ10,A1BG-AS1,LMO2,HECTD2,MARK3,MAT2A,MEIS1,PPM1L,MITF,MKLN1,MMP16,MOBP,CD200,SESN3,N6AMT1,RSPO2,MYT1,NCAM1,NPR2,SLC11A2,NRDC,SMIM11A,OGG1,ZDHHC22,PAK3,PDE4B,OLA1,TMIE,ANLN,GPSM2,PLXNB3,SH3KBP1,POU3F2,RASGEF1B,PRPSAP2,PIGG,ANKHD1,PTK2,SPDL1,TMEM260,OCIAD1,PTPRG,ACSM5,RIPOR1,NWD1,ENOX1,REV3L,RFX3,KCTD17,MYH14,ROBO2,MRAP2,RPL15,ACER3,LRRK2,SATB1,DRAXIN,STUM,SUPT20H,RASA3,SGK1,SCG5,ITSN1,SH3GL3,DOCK10,CHD9,FBXO11,FHOD3,SLITRK3,CNKSR2,ST3GAL3,RPH3A,KANSL3,SEPHS1,SHANK2,LGI3,CPEB4,MYH15,SMARCE1,LIMCH1,KIF13A,CMTR2,SNRPN,SON,SOX2,SOX5,SP2,CLUAP1,ENKUR,HECW1,ZC3H13,RBM26,NFASC,SRPK2,TAB2,ITPRID2,ZC4H2,LRRC4,SS18,DIP2A,PHLDB1,GANAB,SEPT3,FGD4,ANKRD28,KAZN,DDHD2,TBX15,ATMIN,DMXL2,WDR7,NAT16,USP32P1,DICER1,ZFPM2,HHIP,ZFP91,TMPO,DAAM2,KCTD2,TPM2,PDSS1,NEIL2,TRO,TRPC1,TRPC3,SGK3,SLAIN1,PLEKHH2,PLPPR2,VSNL1,CFAP298,PCDH20,ZIC3,ELFN1,ZNF70,LYPD6,FTSJ1,CA10,EMSY,GDPD5,TMEM178A,GAL3ST3,KCNAB1,TRAM2-AS1,NHSL1,PIANP,ST8SIA2" MicroRNA hsa-miR-449a:TargetScan hsa-miR-449a TargetScan 2.75E-100 1.54E-96 1.68E-99 1.55E-98 186 549 "ABR,ASIC2,ADCY5,CCDC85A,ADD2,PTCHD1,AP1B1,MTUS1,GPR158,HECW2,KCTD16,LRRC7,ALCAM,PITPNM2,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,DGKZ,PDXK,NCOA1,ATP1A2,MTMR9,OSGIN2,CACNA1E,CACNA2D1,INA,DGKI,EVI5L,LGI1,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,NRXN2,NMT2,MAP4K4,RTTN,MYRIP,CLOCK,CREB5,CSF1R,CNTNAP2,PPP1R16B,CTNND1,CTNND2,FAM131B,NOS1AP,MYADM,PHF19,LIN54,RIMS3,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CALN1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,CACNG2,ACSL4,SCML2,CAMSAP1,FOXG1,AGAP2,DPYSL4,FUT9,B3GAT1,GAB1,GABRA3,GABRB1,BRPF3,GHDC,INPP5K,CPLX2,GFRA1,LOXL3,GNAO1,GPR12,GPR22,GPR26,GRID1,GRM7,CELF3,FRMD5,ARHGAP36,HMGB1,HNF4G,IGSF1,IL6R,KCND3,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,MDM4,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,NEUROD2,PDE3A,PDE4B,PDGFRA,GPR85,GDAP1L1,CDIP1,SDK2,FAT3,PRKACB,PKIA,PROX1,RELN,PTPRD,EML5,RALGDS,FAT4,RAP1GAP,RAP1GDS1,ARID4A,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,LGR4,AMER2,SATB1,ATXN7,SCN2B,ELMOD1,GALNT10,MRAS,ITSN1,MYO18A,FAM81A,EPN2,LRRC55,CCDC88A,PALLD,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,C3orf70,FAM208A,CNTN2,ATMIN,SATB2,PSD3,NSD1,CRTC1,AHCYL2,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,LMAN2L,NAV3,RGS7BP,MARCH8,CERS6,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-34c-5p:TargetScan hsa-miR-34c-5p TargetScan 2.75E-100 1.54E-96 1.68E-99 1.55E-98 186 549 "ABR,ASIC2,ADCY5,CCDC85A,ADD2,PTCHD1,AP1B1,MTUS1,GPR158,HECW2,KCTD16,LRRC7,ALCAM,PITPNM2,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,DGKZ,PDXK,NCOA1,ATP1A2,MTMR9,OSGIN2,CACNA1E,CACNA2D1,INA,DGKI,EVI5L,LGI1,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,NRXN2,NMT2,MAP4K4,RTTN,MYRIP,CLOCK,CREB5,CSF1R,CNTNAP2,PPP1R16B,CTNND1,CTNND2,FAM131B,NOS1AP,MYADM,PHF19,LIN54,RIMS3,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CALN1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,CACNG2,ACSL4,SCML2,CAMSAP1,FOXG1,AGAP2,DPYSL4,FUT9,B3GAT1,GAB1,GABRA3,GABRB1,BRPF3,GHDC,INPP5K,CPLX2,GFRA1,LOXL3,GNAO1,GPR12,GPR22,GPR26,GRID1,GRM7,CELF3,FRMD5,ARHGAP36,HMGB1,HNF4G,IGSF1,IL6R,KCND3,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,MDM4,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,NEUROD2,PDE3A,PDE4B,PDGFRA,GPR85,GDAP1L1,CDIP1,SDK2,FAT3,PRKACB,PKIA,PROX1,RELN,PTPRD,EML5,RALGDS,FAT4,RAP1GAP,RAP1GDS1,ARID4A,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,LGR4,AMER2,SATB1,ATXN7,SCN2B,ELMOD1,GALNT10,MRAS,ITSN1,MYO18A,FAM81A,EPN2,LRRC55,CCDC88A,PALLD,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,C3orf70,FAM208A,CNTN2,ATMIN,SATB2,PSD3,NSD1,CRTC1,AHCYL2,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,LMAN2L,NAV3,RGS7BP,MARCH8,CERS6,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-34a-5p:TargetScan hsa-miR-34a-5p TargetScan 2.75E-100 1.54E-96 1.68E-99 1.55E-98 186 549 "ABR,ASIC2,ADCY5,CCDC85A,ADD2,PTCHD1,AP1B1,MTUS1,GPR158,HECW2,KCTD16,LRRC7,ALCAM,PITPNM2,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,DGKZ,PDXK,NCOA1,ATP1A2,MTMR9,OSGIN2,CACNA1E,CACNA2D1,INA,DGKI,EVI5L,LGI1,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,NRXN2,NMT2,MAP4K4,RTTN,MYRIP,CLOCK,CREB5,CSF1R,CNTNAP2,PPP1R16B,CTNND1,CTNND2,FAM131B,NOS1AP,MYADM,PHF19,LIN54,RIMS3,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CALN1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,CACNG2,ACSL4,SCML2,CAMSAP1,FOXG1,AGAP2,DPYSL4,FUT9,B3GAT1,GAB1,GABRA3,GABRB1,BRPF3,GHDC,INPP5K,CPLX2,GFRA1,LOXL3,GNAO1,GPR12,GPR22,GPR26,GRID1,GRM7,CELF3,FRMD5,ARHGAP36,HMGB1,HNF4G,IGSF1,IL6R,KCND3,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,MDM4,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,NEUROD2,PDE3A,PDE4B,PDGFRA,GPR85,GDAP1L1,CDIP1,SDK2,FAT3,PRKACB,PKIA,PROX1,RELN,PTPRD,EML5,RALGDS,FAT4,RAP1GAP,RAP1GDS1,ARID4A,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,LGR4,AMER2,SATB1,ATXN7,SCN2B,ELMOD1,GALNT10,MRAS,ITSN1,MYO18A,FAM81A,EPN2,LRRC55,CCDC88A,PALLD,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,C3orf70,FAM208A,CNTN2,ATMIN,SATB2,PSD3,NSD1,CRTC1,AHCYL2,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,LMAN2L,NAV3,RGS7BP,MARCH8,CERS6,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-449b-5p:TargetScan hsa-miR-449b-5p TargetScan 2.75E-100 1.54E-96 1.68E-99 1.55E-98 186 549 "ABR,ASIC2,ADCY5,CCDC85A,ADD2,PTCHD1,AP1B1,MTUS1,GPR158,HECW2,KCTD16,LRRC7,ALCAM,PITPNM2,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,DGKZ,PDXK,NCOA1,ATP1A2,MTMR9,OSGIN2,CACNA1E,CACNA2D1,INA,DGKI,EVI5L,LGI1,NUMBL,CACNA2D2,FOXN3,LHX2,CLCN3,NRXN2,NMT2,MAP4K4,RTTN,MYRIP,CLOCK,CREB5,CSF1R,CNTNAP2,PPP1R16B,CTNND1,CTNND2,FAM131B,NOS1AP,MYADM,PHF19,LIN54,RIMS3,BRINP1,PITPNC1,ELMSAN1,KIAA0753,SEC16A,RPS6KL1,CALN1,CPEB2,RCAN1,E2F5,APH1A,RGS17,C8orf37,PAN3,NRN1,CACNG2,ACSL4,SCML2,CAMSAP1,FOXG1,AGAP2,DPYSL4,FUT9,B3GAT1,GAB1,GABRA3,GABRB1,BRPF3,GHDC,INPP5K,CPLX2,GFRA1,LOXL3,GNAO1,GPR12,GPR22,GPR26,GRID1,GRM7,CELF3,FRMD5,ARHGAP36,HMGB1,HNF4G,IGSF1,IL6R,KCND3,KCNK3,KCNN3,KCNQ3,MSANTD3-TMEFF1,MAPT,LYPLAL1,ADAM11,MDM4,KITLG,PPM1L,MPP2,DBNL,ADAM22,MYCN,NEUROD2,PDE3A,PDE4B,PDGFRA,GPR85,GDAP1L1,CDIP1,SDK2,FAT3,PRKACB,PKIA,PROX1,RELN,PTPRD,EML5,RALGDS,FAT4,RAP1GAP,RAP1GDS1,ARID4A,RET,RFX3,RIC8B,KLHDC8A,CYB561D1,LGR4,AMER2,SATB1,ATXN7,SCN2B,ELMOD1,GALNT10,MRAS,ITSN1,MYO18A,FAM81A,EPN2,LRRC55,CCDC88A,PALLD,FAM126B,ERC1,PEG10,ARHGAP26,POGZ,C3orf70,FAM208A,CNTN2,ATMIN,SATB2,PSD3,NSD1,CRTC1,AHCYL2,CSMD1,DOK6,RGMB,PDSS1,PLEKHH2,BCL2L13,MGAT5B,KLC2,POLR3H,LMAN2L,NAV3,RGS7BP,MARCH8,CERS6,JMJD1C,NETO1,JPH3" MicroRNA hsa-miR-224:mirSVR_highEffct hsa-miR-224:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.42E-100 1.92E-96 2.09E-99 1.93E-98 267 1151 "ACLY,RBM10,ADAR,KLHL32,TMEM132B,ADCY6,SLC12A5,BEND6,SLC44A5,GPR158,PCDH10,AMPD3,APBA2,API5,USP37,DNAH17,ASPH,RASL11B,DDX3Y,SLC4A4,ATP1B3,ZNF582,DPY19L3,TTLL9,SEC11C,BID,BMPR1B,ST3GAL5,CACNA1B,KALRN,VSTM2A,CAST,NFS1,TMEM257,CDC27,CDC42,CCPG1,CIART,CHN1,MAP4K4,ARMC8,AKAP6,LETMD1,ZNF521,IGDCC3,HS3ST5,CHD1L,NCOR1,CSNK1E,PDE4DIP,USP6NL,KCTD8,TMEM170A,GIT2,ARMCX2,MYEF2,HP1BP3,FBXL5,COPS7A,RHOBTB1,WDR20,KIF19,SEC16A,DNM1,USP3,CPEB2,DPYSL2,DTNA,MAMLD1,EDIL3,FAM135B,EDNRB,HIPK3,FRY,EFNA3,FAM13A,MBNL2,ELAVL2,EPB41L2,STX2,FAM198B,SH3YL1,ACSL4,EFEMP1,GORAB,POLR1B,FGF14,FGFR1,SUCO,MEX3B,SEC23B,FLT1,PSD2,SLC37A3,ZCCHC17,FAM49B,NPTN,ATP2C1,ZNF512,OGA,BRPF3,ARPP21,ERAP1,ACSS1,IGSF5,GK,TCERG1,GLS,TNRC6A,ZNF638,GPM6A,EML4,GRIA4,GRIK4,PRDM5,PSIP1,RASSF8,LINC01102,ELOVL5,HMGCR,SOWAHA,RBPJ,IL6ST,NME9,ITGAM,KCND2,KCNMA1,KCNN2,STMN1,LMO2,PACRG,MAP4,MARK1,MATN3,MBNL1,SYT9,LRP1B,SRSF12,AFDN,BLOC1S2,MSRA,NRBP2,SCG3,LYRM9,NAP1L1,NELL1,DNHD1,NRCAM,NUCB2,GPR137C,PAK3,CNTN3,PDE4D,PDGFRA,BEST3,PFKFB2,PFKFB3,PIK3C2A,HMGCLL1,PURG,STRN3,POU3F2,PPP3CA,KANSL1,GRAMD1C,MASP1,RELN,WBP1L,APTX,SYTL2,GON4L,WDR25,PXK,ZSCAN32,PTX3,ZNF615,OXR1,RADX,RDX,SLC6A15,ERI2,RFX4,RGS4,SLC25A36,ZFHX4,EXD2,PCMTD2,CCDC102B,EPHA10,FBXW7,ATAT1,SCP2,CASC3,ITSN1,ARX,ZNF365,PPP4R3A,EPN2,RUFY2,SLC11A1,ELMO2,ATF7IP,ZFP1,RIMS1,PDZD2,MYT1L,KDM3A,ZNF423,ZBTB43,CLASP2,POGZ,NKAIN2,SS18,ELOVL4,AJAP1,SYNE2,NUDT10,SYT1,DNMBP,TBCEL,ZFP90,TCF12,SYNE1,NAT16,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,KCTD2,NPL,SYNPO2,SMUG1,AMACR,TRPC1,TSN,TTC3,TUBB2A,FAM155A,MEAF6,VLDLR,ZBTB14,TRIM9,FSTL5,SMARCAD1,EMSY,SLC17A6,DNAH10,AMN1,MRPL47,DOCK8,RTN4,KAT6A,HNRNPA3,ACTR3B,ADAMTSL3,ZNF248,MSRB3,ZDHHC20,IFT88,NETO1,SLC4A10" MicroRNA hsa-miR-1261:mirSVR_highEffct hsa-miR-1261:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-100 1.98E-96 2.16E-99 1.99E-98 249 1004 "ACTN2,ADAR,PWWP2A,ZNF608,HACE1,OSBPL1A,FAM135A,SYT13,LCORL,KCNAB2,UPRT,MIER1,TMEFF1,ARHGAP5,ZBTB10,ASTN1,TMEM108,EIF4G3,ZNF583,SLC2A11,ADAM23,ST3GAL5,CDK5R2,LURAP1,CALB1,PTBP2,CANX,SLC25A14,SPAG9,USP6,SEPT7,CDC27,CCPG1,CFL2,SRSF11,SOCS6,CHN1,CASC2,NRXN1,TPP1,CLTC,TJP2,NIPBL,ANKRD44,GDA,CSF2RA,OSBPL3,VCAN,DCAF4,EDRF1,TCAF1,RIPOR2,FRMPD4,MAML1,DAPK1,PABPC5,ARMCX2,YTHDC1,C8orf34,MYEF2,MAGI2,RABGAP1L,DMD,CPEB2,DRD1,E2F6,EDNRB,SEMA3D,EGFR,EIF4G2,PLEKHA1,TUBD1,ANKRD13B,TMEM74,RASL12,EXTL2,EYA1,FAM198B,WAC,TMEM132C,ZIC4,CEP78,POLK,FOXM1,SGIP1,JKAMP,NBEA,ZBED3,ATP2C1,AHCYL1,ZMYND11,ADAM28,MALT1,GLS,TOX3,KIAA1958,FUT10,PCLO,GRIA4,GRM5,KIF3A,PSIP1,MIER3,GABARAPL2,HNMT,NEGR1,SMAP1,USP54,ZNF678,CREG2,KIF5C,STXBP5,TTYH2,LIMS1,LMO2,HECTD2,NCOA7,C2orf80,MEIS1,PPM1L,POC1B,WDR49,MSR1,MXI1,NF1,NFE2L2,P2RX7,PAH,GLIPR1L2,ETFRF1,PDCD2,PDGFRA,PIK3R1,ZNF655,SNX10,PLP1,HMGCLL1,PMP2,STRN3,RC3H2,SLC36A4,PRKAB2,PRKCB,GRAMD1C,GON4L,PTHLH,PTK2,TMEM260,PTPRD,PTPRZ1,ACSS3,OXR1,SLC6A15,RGS4,SEC61A2,SLC25A36,RNASEL,RPRD1A,CCDC82,CARF,NEK11,ZC3H14,GLDN,ACER3,RPS20,KCNIP1,RYR3,FAM192A,AMER2,SEMA6D,SATB1,FNIP1,SELL,CASC3,SCAF8,ZFP30,NTNG1,CHD9,CCDC92,FAM81A,KDM4D,SEPHS1,CCDC88A,KBTBD4,SLC15A2,BTBD7,SLC22A4,ZFP1,CXXC4,MAST1,TMCC1,UNC5B,KIF1B,RBM26,SRPK2,ATP10B,POGZ,ITPRID2,ERBIN,NEK4,SEPT3,KLHL7,SYT4,TACR1,KLHL4,CUX2,ZEB1,TRIM2,WDR7,ARHGEF12,USP32P1,FRYL,RNF216P1,CRB1,C18orf54,AP4E1,ZNF34,GZF1,HEY1,LRRC8A,DAAM2,RBFOX2,FNDC5,USP1,ZNF709,WIPF1,ZNF781,NSD2,GUSBP1,SLC13A3,KCNK12,ZBTB14,ZIC2,ZIC3,TCEAL7,FSTL5,EMSY,VPS35L,PCDH15,NAV3,RGS7BP,FZD3,DOCK8,KAT6A,CASC15,TRAM2-AS1,RNF170,NETO1,CBLN2" MicroRNA hsa-miR-125b:mirSVR_lowEffct hsa-miR-125b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-100 2.02E-96 2.19E-99 2.02E-98 302 1456 "ABAT,ACADM,ACHE,SYS1,NDRG3,PLEKHG5,ADD1,ERMN,LRFN2,BEND6,MTUS1,SNX32,RTL9,TXNDC16,CC2D2A,MARCH4,PI16,PKP4,KCNAB2,APC,DGKZ,NT5C3B,TNRC6C,API5,AQP6,SPTBN4,SLC4A4,SLC2A11,NOL4,DOCK11,SNAI3-AS1,CFLAR,KSR1,BMPR1B,SYNJ1,SCAPER,CACNA1B,CACNA1E,DDR1,DIRAS1,ISPD,ARHGEF1,SCARB1,ARHGEF2,CDH8,CBARP,CASC2,RAB33A,RAB28,KIAA1549L,NRXN1,FADS2,DNAJB5,ARHGEF6,ARMC8,ANKRD35,SUMF2,MFSD4A,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,TENM4,SIPA1L1,NCAN,APPL1,PHF14,GREB1,FAM131B,ECE2,NOS1AP,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,PLEKHM1,HEPH,RUSC2,ZC3H11A,SV2A,RPS6KL1,DPH1,DTNA,DTNB,ABCC5,FAM135B,PHC2,SYT15,CNNM1,SEMA3D,PHF20L1,TMEM132E,PLEKHA1,ANKRD13B,MRPL10,ANKMY1,SCML2,FCGR1A,FKTN,STRADA,ZNF589,FER,PRKAG2,SMC2,ARFGAP2,DACH2,GPR153,HHIPL1,AP4B1,NRG3,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,GGT7,CRCP,TCERG1,GLS,ZNF638,LOXL3,GNAS,GOLGB1,LILRA2,CCDC184,LPAR4,TMEM121B,CECR2,PCLO,RAPGEF4,GRB10,GRIA2,SPACA9,RASSF8,HAS2,PADI2,PTGDR2,MAN1B1,HRH3,TNFAIP8L3,SYNPO,HMGCR,HNF4G,OPALIN,NKD1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KCNA1,KHK,KIF5A,KIFC3,SYTL4,VWA5A,HECTD2,NCOA7,LSS,MAP2,MAP6,SYT9,ADAM11,MIA2,MOBP,MSI1,C10orf105,MYO7A,NEFM,NUCB2,IGSF11,DPY19L2P2,PDE3B,PDGFRA,ZDHHC8,CAMKV,ZNF655,PLCB2,RETREG2,POLG,POU3F2,MINDY2,PTPA,PPP2R5C,PRKCZ,MAPK10,PROX1,VPS13C,PSMD13,CNTLN,PTH1R,PTK2,PTPRD,PTPRE,C1orf109,FAT4,ZDHHC14,SLC6A15,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,SNX22,EPHA10,STK32B,EMID1,LRRK2,MEG3,SCN2B,SCP2,ASIC4,CASC3,ITSN1,KIF16B,MYO18A,MAGI3,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,SLCO1A2,LGI3,ABTB1,ANKRD36,SNRPN,UNC80,DOP1A,WDTC1,ENKUR,GLT8D1,ZC3H13,SPTB,NFASC,SS18,SSPO,NCDN,ELOVL4,SEPT8,ADHFE1,FGD4,SYN2,SYPL1,SLC37A2,TACR1,TMEM136,SATB2,TCF7,RPGRIP1L,WASHC4,TF,DICER1,CRB1,GPR161,AKTIP,BHLHB9,LRRC8A,TMOD1,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,BCL2L13,PORCN,ELFN1,GPR158-AS1,CRB2,LYPD6,TMEM198,EML6,MAP3K12,PRDM2,CSDE1,STOX2,ADAMTS9,PCDH15,SLC17A7,CAB39L,WIPF2,PLSCR4,PARP11,GOPC,UBE3B,TMEM63C,ZNF248,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-139-5p:mirSVR_highEffct hsa-miR-139-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.03E-100 2.27E-96 2.46E-99 2.27E-98 235 895 "RALGAPA1,ACADM,ACLY,CLK4,NDRG2,KLHL32,AXIN2,SLC12A5,ERMN,PWWP2A,CC2D2A,TAOK1,LRRC7,PCDH10,FAM135A,LRCH2,ANK2,EP400,PKP4,UPRT,DDO,IGDCC4,PCDHGB4,ZBTB10,STX16,ADGRB3,BBS2,SCAPER,CA12,CAMK2D,SPAG9,C1orf52,CDC42,MAGI1,CDO1,CCPG1,ADGRG1,RCBTB2,SYNPR,CLCN4,FHL5,ARHGEF6,ARMC8,HS3ST5,CREM,GDA,SOCS5,USP6NL,TOX,ARMCX4,ZEB2,HP1BP3,KIAA0319,SPOCK3,CHRDL1,DMD,ABCC5,DNM1L,EBF1,TSPAN5,YAF2,MBNL2,EIF4G2,ELAVL2,PLEKHA1,MRVI1,CLVS1,SCML2,KIAA1109,POLK,UBE2E3,FLT1,PSD2,STAMBP,ATP2C1,STAU2,FYB1,GABRA1,ZNF234,ERAP1,DNER,GATM,GLI2,TNRC6A,MSL3,PCDH11X,ZNF638,CBX1,GPM6A,GPR17,LPAR4,GPR37,CNTRL,ATP2B1-AS1,GRIK2,GRM1,RASSF8,ELOVL5,HMGCR,HNF4G,FAM95B1,ZNF181,ZNF678,KCND2,CLVS2,KCNMA1,PAXBP1,HECTD2,LSS,PACRG,MAP2,MARK1,LYPLAL1,MAT2A,MBD1,SYT9,MEIS2,AFDN,MRPL42,MYO9A,NAP1L3,NDP,CNOT4,NPPA,NPTX1,NRCAM,OCRL,GLIPR1L2,PCDHGC3,PDE3A,PDE4A,PDE4D,A2ML1,XRN1,PMP22,LRP12,PSAT1,SCHIP1,NXPH1,DRAM2,PPM1B,PPP3CB,MAPK9,VPS13C,PTPRD,EML5,PTPRZ1,PEX5,ZNF493,RASGRF1,RLBP1,PBRM1,RPRD1A,ZNF532,MRAP2,TCP11L1,FAM161B,WLS,ZNF331,LRFN5,SCN3A,RASA3,ARX,FHOD3,R3HDM2,WDR47,TMEM132D,ATF7IP,MYH15,KIF13A,WDTC1,SOX1,SOX5,KIF1B,TROVE2,ZNF302,SST,ERBIN,AJAP1,PLCB1,SYT4,FAM208A,SATB2,ZFP90,ZEB1,TCF12,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,SZT2,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,PCDHB7,AKNA,GPRIN3,FRYL,TEK,TP53BP2,TPD52,C9orf85,TRPS1,DCBLD1,HIRA,UBE3A,P2RY12,CLDND1,RICTOR,LGI4,ZNF19,TRIM9,ELFN1,NDRG4,ZNF177,FSTL5,ZSCAN26,ANKS1B,SPIRE1,ADAMTS9,PCDH15,FZD3,RTN4,PAK5,KAT6A,NUP214,JMJD1C" MicroRNA hsa-miR-2114:mirSVR_lowEffct hsa-miR-2114:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.88E-100 3.30E-96 3.58E-99 3.30E-98 293 1378 "TTYH1,KCNH8,ASPHD1,CLK4,SYS1,ADAR,GALNT16,ADD3,CDC7,ERMN,KIAA1211,RNF150,HECW2,AK2,SEMA6A,ALCAM,PCDH10,TRMT9B,AMPD2,AMPD3,CDC42BPA,ANK1,ANK2,ANXA7,APBB1,EPB41L5,TNRC6C,SHTN1,AQP6,ARNTL,LINC00173,ZBTB10,NUMB,ASTN1,MTMR9,CARMIL3,BCL7A,BTK,CASTOR3,CDK5R2,PTBP2,VXN,SYT6,ISPD,CBLN1,USP6,ARHGEF1,SCARB1,DGKI,LGI1,UBE2L6,RCBTB2,SLIT2,RAB28,NRXN3,CLU,TPP1,NMT2,AKAP7,FAM149A,COL11A2,COX4I1,HAPLN1,CS,FEZ1,CX3CR1,KIAA0408,RIMS3,SPOCK2,ARMCX4,MYEF2,HP1BP3,KLHL3,BLOC1S6,DDX46,GUCD1,PARD6A,SV2A,EXOG,RAB39B,DMD,NYAP1,CASP8AP2,DPP6,PDCD6IP,E2F5,E2F6,EDN1,FAM135B,EDNRB,HEYL,TMTC1,FAM13A,EGFR,MRO,PLEKHA1,EPB41,NCALD,SPEG,MRPL10,RTN3,ADGRV1,F5,CACNG3,TBC1D16,ACSL4,ATP8A1,FCGR1A,CHST15,FCGR3A,ZNF589,GTF2IRD2,OLFM1,SPSB4,CAP2,RGPD5,SEMA6C,ATP13A4,UFM1,ARFGAP2,CAMKK2,ZNF605,CELF1,GABRA5,HBS1L,ARPP21,ZNF274,ERAP1,GGTA1P,LYVE1,SPIN1,GPM6A,GPR12,CCDC184,RFFL,RNF165,TMEM25,KAT7,RASSF8,PTGDR2,MIER3,HSD17B1,LRRC75A,ICA1,TJAP1,SCRT2,IL11RA,ITGAM,ITPKB,SLC35G1,KIF5A,KIF5C,LAMP2,LOC100128239,AQP11,CHIC1,MEIS1,MEIS2,KITLG,PPM1L,BCO1,MYO7A,RCOR2,NEFH,NFIA,NOVA1,NUMA1,OPHN1,P2RX7,GPR173,GNG2,NALCN,ST8SIA5,PLXNB1,ING3,POLR2F,PCDHB17P,PPP3CB,RASGEF1B,MAPK4,CNNM2,CNTLN,PTN,PTPRB,PTPRE,PTX3,PEX5,ZSCAN2,TMEM231,CCDC40,FAM66C,RALGDS,SH3TC2,OXR1,RFX5,RGS3,KCTD17,KIF7,NUDT11,RNASEL,ZFHX4,TMLHE,ELP2,SGSM1,LGR4,PTGR2,ATAT1,RTKN,FAM192A,S100B,ATXN7,HOGA1,SCN4B,LRRTM4,TRA2B,SH3GL2,CPEB3,MAGI3,AMBRA1,ST3GAL3,SLA,ZNF365,SLC1A3,URGCP,SLC2A5,FAM214B,SIRT2,SLC11A1,SLC12A2,NAPB,CPEB4,GKAP1,PALLD,UNC80,KDM4B,SON,SOX2,TNIK,KIF21B,PEG10,ZBTB43,TAB2,SS18,NCDN,PHLDB1,NSFL1C,SYT11,VPS13A,COBL,TACC1,CAMTA1,FAM208A,TMEM136,SIN3B,AHCYL2,CRB1,HHIP,C5orf64,SEZ6L,C9orf85,WBP2,SMUG1,LRTM2,HSPBP1,GORASP1,SLAIN1,BEST1,WIPF1,NSD2,RICTOR,ZBTB14,ZNF24,ZNF28,ELFN1,ZNF45,GPR158-AS1,LYPD6,ANKS1B,DHX33,SLC30A4,LINC02210,STOX2,CIAPIN1,GAL3ST3,SLC17A7,SNX27,ST7,NUP214,TRAM2-AS1,PIANP,NETO1,SLC4A10,GAN" MicroRNA hsa-miR-34a*:mirSVR_highEffct hsa-miR-34a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.90E-100 3.32E-96 3.59E-99 3.31E-98 258 1079 "RALGAPA1,SDE2,KCNH8,ACLY,DSCAML1,KIDINS220,PCDH19,RTL9,OSBPL6,TAOK1,ADGRF5,C1QTNF3,LRRC7,BCAR3,KIF6,ANK2,ANK3,PKP4,PARG,APAF1,UPRT,GPAM,ALS2,MIER1,PDXK,PLA2G4C,ASPH,ATP2B1,CDK5R1,SCAPER,JAZF1,THSD7A,CALM1,CAMK2D,VSTM2A,KRIT1,LRBA,CDC42,CFL2,CHN2,NDST3,NMT2,CLTC,SULT4A1,CNN3,CNTFR,FAM149A,AKAP6,SLC4A8,RTTN,MFSD4A,SLC35F1,CPS1,AKAP12,HAPLN1,ABCG1,FEZ2,CSNK1G3,PDE4DIP,EDRF1,CYBB,HDAC9,FGFR1OP2,PHF19,ZFYVE16,JAKMIP2,ZEB2,BLOC1S6,DDX46,RHOBTB1,PLPPR4,SV2B,G3BP2,ZNF582-AS1,SLC25A18,PDCD6IP,ECM2,DNAJB6,DYRK1A,GOLT1B,AASDH,ANKRD46,FCF1,KLHL5,FSD1L,SH3GLB1,EFNB3,PHF20L1,EGFR,EIF4G2,PLEKHA1,GPHN,GMPR2,ACSL4,FCGRT,FDFT1,GORAB,SEC24B,FER,FGF14,FGFR1,POLK,RGPD5,TACC2,TMEM107,SPECC1,STAMBP,B3GAT1,AP4B1,SDCBP2,STAG2,GABRG2,CAB39,GAD1,C15orf41,PCDH17,PPARGC1A,BRD8,COPS8,SPIN1,RAB30,GNAS,LNX1,EML4,PCLO,RFFL,GRIK2,PRDM5,HAS2,ZHX1,FRMD5,TNFAIP8L3,HMGB1,HMGCR,HNMT,BTBD17,RBPJ,DOCK7,LIX1,ZNF678,KCNH2,KCNK2,KIF5A,LAMP2,PAXBP1,NCOA7,MAOB,MAT2A,MITF,ERICH3,MSR1,MT1M,MXI1,RTL5,NEUROD1,CNOT4,DNHD1,HCN1,CHAMP1,LOC100128398,GPR137C,CNTN3,OLA1,ABCB1,HMGCLL1,PPP3CB,RANBP3L,MAPK9,RELN,SAMD9,LRRC49,SNRK,PXK,SPDL1,ACSM5,RAB5B,RAD51D,ZNF493,ARID4A,SLC6A15,LGI2,MRAP2,MCMBP,RPS20,RTN1,TMEM156,RMI1,SCN7A,SCN8A,LINC00461,ITSN1,NLGN1,FAM81A,SLC12A2,ATF7IP,TET1,SORCS3,SMARCE1,RCOR3,MBD5,SNRPN,PALLD,USP33,SP4,KIF1B,CDK19,LMO3,CLASP2,ITPRID2,SSTR2,NKAIN2,LRRC4,TTBK2,ADHFE1,SYT11,FGD4,VPS13A,SYT1,COBL,SYT4,CAMTA1,CAMSAP2,UNC5D,ADGRL3,EHBP1,DMXL2,ZEB1,RPGRIP1L,SYNE1,ARHGEF12,LEFTY2,CSMD1,TPM3,SYNPO2,RUNDC3B,TTTY15,TTC3,TMEFF2,CADM1,UGT8,P2RY12,LAT2,WRN,NPDC1,RICTOR,XPO1,ZFP37,ZIC3,ZNF711,ZBTB38,ZSCAN26,STMN4,PRDM10,RNF103,URM1,ADAMTSL3,ZNF248,NETO1" MicroRNA hsa-miR-376a:mirSVR_highEffct hsa-miR-376a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.04E-100 3.96E-96 4.28E-99 3.94E-98 266 1146 "NCKAP5,TMEM132B,DSCAML1,PWWP2A,PTCHD1,INTS2,NME5,OSBPL8,HFM1,PCDH10,LRCH2,ANK2,APC,LGR5,TMEM263,ZFYVE28,ASPH,ATP2A2,ATP2B1,ADGRB2,SNAI3-AS1,BARD1,DCAF5,PROM1,SCAPER,MTMR3,CACNA1G,CA8,SLC25A14,VXN,SYT6,CH25H,RUNX1T1,MTMR7,INA,SLC16A4,LRBA,SEPT7,CDC42,CDO1,SRSF11,PPT2,NRXN1,QKI,NIPBL,BTF3L4,ABI3BP,MFSD4A,HS3ST5,CP,FAM171B,HAPLN1,ANKRD44,CSNK1G3,ATRNL1,PDE4DIP,RIMS2,EDRF1,HDAC9,GAPVD1,LIN54,IP6K1,MYEF2,COPS7A,ALKBH8,WDR20,EXOG,DNAH9,DMTF1,DPP6,ECM2,ABCC9,E2F5,WDPCP,EDN1,FAM135B,RASGRP1,TMTC1,SIDT2,ELAVL2,EML1,DCTN4,EPB41,EPHA5,RABEPK,SRRM1,PRMT5,POLR1B,POLK,ATP2C1,KHDRBS3,ST6GALNAC3,NSG1,PHYHIPL,MEGF11,GABRA2,GALNT15,HBS1L,ZMYND11,ZNF559,SULT1C4,ADAM28,MALT1,TOX3,CBX1,FERMT2,WDFY3-AS2,PSRC1,GRIA4,GRIK2,GRIK5,NR3C1,CLASRP,HAS2,MIER3,HNF4G,SMAP1,DOCK7,ITPKB,METTL21A,OLFM3,KCNC2,KCNH2,STXBP5,LAMP2,LIG4,PAXBP1,PIK3AP1,MBD1,MDM4,POC1B,MMP16,CD200,GIT1,LAYN,MYO9A,NCAM2,ALDH1L2,CNOT4,OPHN1,KCNK10,PAK3,DPY19L2P2,PDE3B,PDE4B,PDGFRA,SLC10A4,OLA1,FAM218A,CCSER2,NLE1,PMP2,LRP12,ING3,SPATA6,MED1,PPP2R5E,PPP3CB,PRKACB,CEP41,PKN2,MASP1,VPS13C,PSMD13,PTHLH,ELOVL2,SPDL1,STK32A,PTPN13,OCIAD1,ZNF615,RAB5B,USP47,ARID4A,GAL3ST4,SLC6A15,ZYG11B,ERI2,RFX4,RGS3,SETD5,TMLHE,ROBO1,RORB,TMEM100,NEK11,EPHA10,ZNF671,AP1AR,SALL1,MIR124-2HG,SLC30A10,COPZ1,FERMT1,DOCK10,SHC4,CHD9,FBXO11,SLC6A1,TET1,MAST1,SORCS3,CDK5RAP2,MYH15,RCOR3,IFT122,RIMS1,MBD5,UNC80,MYCBP2,SPP1,KDM4C,IDI2-AS1,CDK19,SPART,TAB2,ITPRID2,LARP4,NKAIN2,ARHGEF9,ANKRD28,SYT4,TBCEL,CUX2,PCDHB9,FAM200B,TIAM1,TJP1,ASXL3,CABIN1,RBFOX2,TPD52,PRMT8,ELP5,TRIO,ZMYND8,KCNE5,RFTN2,TMEFF2,UGT8,VLDLR,VSNL1,WIPF1,ZIC3,KCNT2,CELF4,ZNF189,ANKS1B,SMARCAD1,DHX33,ZNF225,SLC30A3,CSDE1,RNF103,SCG2,NAV3,PPP1R3F,SLC17A6,PARP11,FZD3,PAK5,PHTF2,ADAMTSL3,JMJD1C,IFT88,JPH3" MicroRNA hsa-miR-154*:mirSVR_highEffct hsa-miR-154*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.16E-100 4.02E-96 4.35E-99 4.01E-98 249 1007 "NCKAP5,ACTN1,CSMD3,SLC12A5,PWWP2A,AP2A2,ZNF608,HECW2,AGT,NME5,OSBPL6,ARHGAP20,CDC42BPA,PPFIA2,SUGT1P4-STRA6LP-CCDC180,API5,PPP4R4,TMEM263,RASL11B,ASTN1,SLC4A4,ATP2B1,SEC11C,CFLAR,CALB2,CAST,CCK,LDB2,C1orf52,REPS2,CDH2,ZMYM4,RCBTB2,SRSF11,SYNPR,NGEF,ABCG2,TMEM184B,CNR1,COL9A1,ABI3BP,CRHBP,GDA,ATRNL1,APPL1,ST18,USP6NL,DOCK4,GAPVD1,FRMPD4,TOX,LIN54,KIAA0586,DAPK1,YTHDC1,C8orf34,ZEB2,ZBTB24,MYEF2,MAGI2,ZC3H11A,SMG7,PLPPR4,SGSM2,USP3,DRD1,PDCD6IP,DTNA,DYRK1A,HIPK3,FAM13A,MRO,ELAVL2,SIRPB1,ABCA8,CEP78,GORAB,KIAA1109,CAMSAP1,SUCO,MEX3B,VTI1B,AGAP3,NBEA,NPTN,ARFGAP2,ATP2C1,AP4B1,GAD2,GALC,GALR1,NEU3,TUBA8,PPARGC1A,GK,COPS8,GLS,ZNF638,FERMT2,LNX1,GPD2,GPM6A,TDRKH,GPER1,EML4,RAPGEF4,GRIA4,PSIP1,MAP4K5,HMGCR,HNMT,SMAP1,ZIC5,LRRCC1,INSM1,KCNC1,KCNMA1,KCNN2,KIT,HECTD2,MARK3,MEIS1,MEST,AFDN,MRPL42,BLOC1S2,BCO1,HCN1,LOC100128398,CLDN11,PDE4D,KCTD15,ST8SIA5,EPN1,PDZRN4,TRHDE,ING3,SPATA6,EPB41L4B,POU3F2,PPM1B,PPP2R5E,PPP3CB,PRKACB,PKIA,PRPSAP2,MTMR10,PTPN13,EML5,MARCH1,CEP97,OXR1,RASGRF2,RBBP6,ZDHHC14,RDX,MORC4,RFX3,RFX5,SEC61A2,RNF220,TMLHE,CARF,PNMA8A,PCMTD2,TMEM100,ARMH4,HUNK,WLS,ZNF568,AP1AR,ATXN2,ITSN1,SH3GL2,MAGI3,FAM81A,YPEL4,RAB3GAP1,SLC9A5,ZNF334,SLC20A2,ATF7IP,ANKRD36,LIMCH1,MBD5,SNRPN,PDZD2,MYT1L,KIF21B,KDM4C,RBM26,NPAS3,SPART,SSTR2,ERBIN,ZSCAN29,NEK4,SEPT8,SYNE2,VPS13A,NUDT10,SYN2,COBL,SYT4,TAC1,MTCL1,PJA1,MLST8,ZEB1,RPGRIP1L,PUM2,SIRT1,ITGB3BP,AP4E1,AKTIP,C5orf64,TP53BP1,CDK20,SYNPO2,RUNDC3B,STXBP4,TRPC3,ANO5,SSBP2,RFTN2,TMEFF2,SGK3,UGT8,GUSBP1,ZFP37,ZNF711,ZNF19,ZNF32,KCNT2,FSTL5,EML6,ANKS1B,ZNF225,CADM2,EVI5,TMEM178A,PCDH15,TRIM16L,FAM13C,PHTF2,JMJD1C,ZNF248,SSPN,IFT88" MicroRNA hsa-miR-133b:mirSVR_lowEffct hsa-miR-133b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.74E-100 4.91E-96 5.29E-99 4.88E-98 266 1147 "ACADM,ABHD6,FAM43B,CSMD3,ADCY6,SLC12A5,CDC7,BEND6,AP1B1,SNX32,ALAD,ABCD2,PCDH10,FAM135A,FGD2,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PPFIA3,AQP6,CASK,ARHGDIA,ARNTL,CAPRIN2,PCDHGB4,ZBTB10,DDX3Y,ATM,ATP2B2,ATP2B3,RIPK1,LINC00847,BCL2L2,DST,JAZF1,RAB29,CA8,CALM1,SPAG9,USP6,CBFA2T2,CDH8,LRRFIP1,DIS3L,KMT2C,DLGAP3,FADS2,FAM19A5,QKI,NIPBL,BTF3L4,COL9A2,LETMD1,BAG4,ZNF521,CREB5,ABCG1,TENM4,SLITRK5,SLC45A1,NRSN1,RUBCN,ARHGAP24,ZNF337,DGKB,DGKG,TMEM170A,PABPC5,GIT2,DNAJC6,HEPH,MAGI2,AK5,USP3,DNAJB6,DYRK1A,CNNM1,EFNA3,FAM13A,PHF20L1,SORBS3,TNK2,ERBB2,DUSP27,ANKMY1,REEP2,FAM198B,FCGR3A,FGF1,FGFR1,SCARA3,FOXG1,IP6K2,PSD2,NOP56,CAMKK2,CELF1,STAU2,NRG3,GABRA5,HBS1L,IQGAP2,TMEM8B,SIGLEC8,MYOZ2,SESN1,GGT7,TTBK1,RAB30,ZNF638,OS9,DCLK2,GPR12,TMEM121B,STMN2,GRIA2,ADAMTS13,GRM7,ZNF496,LINC01551,ZHX1,FRMD5,MIER3,AGBL5,HSD17B1,SHISA6,CELF5,LRRCC1,IGSF1,IL6ST,JAK2,KCNA4,KCNA6,KCNJ9,KLHL23,KCNK2,KIF5C,STXBP5,SFXN5,MARK1,IL17D,CHIC1,SAMD5,MYO7A,NCAM2,NELL1,NELL2,NEUROD1,NTRK3,NUCB2,LOC100128398,P2RY1,PBX1,PCDHGC3,PDE1A,PDE3B,GNG2,PFKFB3,SEMA5B,PIK3C2A,KCTD15,NLE1,PRIMPOL,LRP12,TNPO2,FAT3,PPP2R5E,PRKCZ,MAPK4,HYDIN,GON4L,ELOVL2,CCDC40,FAM66C,RET,UBR7,LGI2,GSTCD,NEK11,EPHA10,SPIN3,GLDN,CNTNAP3,SOX8,AP1AR,FAM19A1,CASC3,SFPQ,RASA3,KIF21A,SH3GL3,NTNG1,FNDC3A,ST6GAL1,CNKSR2,PAAF1,ZNF365,PPP4R3A,SLC8A2,ANKRD36,LHFPL4,HECW1,ERC1,UNC5B,PEG10,KIF1B,RBM26,ATP10B,SSTR1,ELOVL4,SEPT8,DIP2A,STXBP1,VAMP1,VPS13A,SYN2,TCEA1,DMXL2,CUX2,TCF7L2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,NAT16,PCDHGA1,DOCK9,PHF24,USP32P1,GPRIN3,SIRT1,DICER1-AS1,GZF1,TK2,DAAM2,KCTD2,SMUG1,TRO,STXBP4,TTC3,ZKSCAN5,WIPF1,LAT2,NSD2,XPO1,ZBTB14,ZNF24,FMN2,MKRN3,ZBTB38,POLR3H,ANKS1B,STMN4,FIP1L1,WIPF2,PHTF2,CBLN2,SLC4A10" MicroRNA hsa-miR-133a:mirSVR_lowEffct hsa-miR-133a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 8.74E-100 4.91E-96 5.29E-99 4.88E-98 266 1147 "ACADM,ABHD6,FAM43B,CSMD3,ADCY6,SLC12A5,CDC7,BEND6,AP1B1,SNX32,ALAD,ABCD2,PCDH10,FAM135A,FGD2,SUGT1P4-STRA6LP-CCDC180,MAGEE2,PPFIA3,AQP6,CASK,ARHGDIA,ARNTL,CAPRIN2,PCDHGB4,ZBTB10,DDX3Y,ATM,ATP2B2,ATP2B3,RIPK1,LINC00847,BCL2L2,DST,JAZF1,RAB29,CA8,CALM1,SPAG9,USP6,CBFA2T2,CDH8,LRRFIP1,DIS3L,KMT2C,DLGAP3,FADS2,FAM19A5,QKI,NIPBL,BTF3L4,COL9A2,LETMD1,BAG4,ZNF521,CREB5,ABCG1,TENM4,SLITRK5,SLC45A1,NRSN1,RUBCN,ARHGAP24,ZNF337,DGKB,DGKG,TMEM170A,PABPC5,GIT2,DNAJC6,HEPH,MAGI2,AK5,USP3,DNAJB6,DYRK1A,CNNM1,EFNA3,FAM13A,PHF20L1,SORBS3,TNK2,ERBB2,DUSP27,ANKMY1,REEP2,FAM198B,FCGR3A,FGF1,FGFR1,SCARA3,FOXG1,IP6K2,PSD2,NOP56,CAMKK2,CELF1,STAU2,NRG3,GABRA5,HBS1L,IQGAP2,TMEM8B,SIGLEC8,MYOZ2,SESN1,GGT7,TTBK1,RAB30,ZNF638,OS9,DCLK2,GPR12,TMEM121B,STMN2,GRIA2,ADAMTS13,GRM7,ZNF496,LINC01551,ZHX1,FRMD5,MIER3,AGBL5,HSD17B1,SHISA6,CELF5,LRRCC1,IGSF1,IL6ST,JAK2,KCNA4,KCNA6,KCNJ9,KLHL23,KCNK2,KIF5C,STXBP5,SFXN5,MARK1,IL17D,CHIC1,SAMD5,MYO7A,NCAM2,NELL1,NELL2,NEUROD1,NTRK3,NUCB2,LOC100128398,P2RY1,PBX1,PCDHGC3,PDE1A,PDE3B,GNG2,PFKFB3,SEMA5B,PIK3C2A,KCTD15,NLE1,PRIMPOL,LRP12,TNPO2,FAT3,PPP2R5E,PRKCZ,MAPK4,HYDIN,GON4L,ELOVL2,CCDC40,FAM66C,RET,UBR7,LGI2,GSTCD,NEK11,EPHA10,SPIN3,GLDN,CNTNAP3,SOX8,AP1AR,FAM19A1,CASC3,SFPQ,RASA3,KIF21A,SH3GL3,NTNG1,FNDC3A,ST6GAL1,CNKSR2,PAAF1,ZNF365,PPP4R3A,SLC8A2,ANKRD36,LHFPL4,HECW1,ERC1,UNC5B,PEG10,KIF1B,RBM26,ATP10B,SSTR1,ELOVL4,SEPT8,DIP2A,STXBP1,VAMP1,VPS13A,SYN2,TCEA1,DMXL2,CUX2,TCF7L2,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,NAT16,PCDHGA1,DOCK9,PHF24,USP32P1,GPRIN3,SIRT1,DICER1-AS1,GZF1,TK2,DAAM2,KCTD2,SMUG1,TRO,STXBP4,TTC3,ZKSCAN5,WIPF1,LAT2,NSD2,XPO1,ZBTB14,ZNF24,FMN2,MKRN3,ZBTB38,POLR3H,ANKS1B,STMN4,FIP1L1,WIPF2,PHTF2,CBLN2,SLC4A10" MicroRNA hsa-miR-577:PITA hsa-miR-577:PITA_TOP PITA 9.41E-100 5.29E-96 5.70E-99 5.25E-98 204 672 "RALGAPA1,CSMD2,USP31,KLHL13,PCDH19,OSBPL8,LRRC7,ARHGAP20,FAM135A,AMPD3,ANK3,APC,USP37,CDC14B,TMEM263,RGS20,CDK13,CHRD,ATM,ATP2A2,ATP2B1,ATP2B2,ATP2B3,MYOM1,FOXK1,CALB1,USP6,SLC16A4,TMEM257,REPS2,LARGE1,MAGI1,CHGA,CHN2,LHX2,KMT2C,NRXN1,QKI,CNN3,SH2B1,CREB5,ATRNL1,SOCS5,NRSN1,RIMS2,ST18,USP6NL,DOCK4,HDAC4,SPOCK2,DBI,DNAJC6,RHOBTB1,SMG7,G3BP2,WDR20,CASP8AP2,PDCD6IP,SNX29,RBM12,MBNL2,KMT5B,TENM1,PLEKHA1,RGS17,TMEM35A,EPHB1,EPS8,EYA1,NRN1,WAC,ACSL4,TAOK3,ATP8A1,FKTN,AFF2,KHDRBS3,DACH2,MPP6,ZNF512,OGA,STAG2,GAD2,AHCYL1,C15orf41,SRRM4,WASF3,CPLX1,DNER,AHDC1,PPARGC1A,TOX3,TNRC6A,GPR37,ADAMTS6,TOX2,KLF12,MIER3,HLF,HMGB1,HNRNPK,NEGR1,SOWAHA,IGF1,USP54,SCRT2,LRRTM3,STXBP5,KTN1,LIG4,SFXN5,MAP2,LRP1B,KITLG,MKLN1,OTOGL,NRCAM,IGSF11,CLDN11,GPR137C,CNTN3,PCDH8,PRTG,GNG2,KCTD15,PLCL1,SMOX,HMGCLL1,TRHDE,LRP12,DRAM2,MED1,DIRAS2,PTPRD,PTPRN2,PTPRO,FAM120C,TMEM145,RDX,RGS7,SLC25A36,PBRM1,SETD5,TMEM100,FBXW7,SPIN3,LGR4,SOX8,CLIP1,SCN2A,SOX6,ZNF821,KIF21A,ITSN1,SH3GL2,PPM1E,SHMT2,FAM81A,SLC6A9,YPEL4,CPEB4,MBD5,SOX5,SOX10,SOX11,SP4,MYCBP2,PEG10,CDK19,LMO3,SRPK2,ARHGEF9,PLCB1,SYP,SYT4,UNC5D,WWC1,AGTPBP1,ZEB1,PUM2,SIRT1,ZFPM2,HEY1,KAT6B,CADM1,BCL2L13,MEAF6,SF1,ZIC3,ZNF711,MICU3,ZBTB38,REEP1,SH3GLB2,SMARCAD1,MAP3K12,CADM2,CSDE1,EVI5,SNX27,WIPF2,KAT6A,HNRNPA3,CPNE4" MicroRNA hsa-miR-765:mirSVR_highEffct hsa-miR-765:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-99 5.99E-96 6.44E-99 5.94E-98 254 1049 "VWA5B2,TTYH1,ASIC2,ACHE,ARID1A,NDRG2,DSCAML1,SLC12A5,MTUS1,OSBPL1A,PCDH10,CNTNAP1,PHYHD1,VAT1L,SPTBN4,LINC00173,PCDHGB4,ATP1B3,MYOM1,ADGRB3,NRP2,SYNJ2,C1QC,CACNA1G,C5,DDR1,CACNB2,THSD7A,KALRN,TRIM41,RUNX1T1,LDB2,CD86,KCNAB3,DLGAP1,TIGD7,SRSF11,CHN2,SYNPR,PPT2,NIPBL,CNTFR,BTF3L4,LETMD1,GAL3ST1,SEC31B,HINFP,CSF1,CSF1R,CSF3R,FEZ1,MICAL2,SUSD5,PLCH2,PUM1,RUBCN,IST1,DAPK1,GIT2,DCT,ELMO1,B3GAT3,MAGI2,SMG7,NTM,CHRDL1,USP3,DTNA,FARSB,TMTC1,CELSR3,EBI3,EGFR,ABI2,OLIG2,VPS13B,SEZ6,EPHB1,SRRM1,RCSD1,SIRPB1,EXTL2,NRN1,PTK2B,TAOK3,CEP78,OLFM1,DLL3,ZNF512,HRASLS5,GABRA3,ZMYND11,C15orf41,INPP5K,CPLX1,NEU3,TUBGCP4,SRCAP,AHDC1,GGT7,GNG3,TDRKH,GRIA2,GRIA4,SERP2,BTN2A1,FAM19A2,TMEM25,KAT7,LINGO1,GUCY1A2,C1orf94,FRMD5,ARHGAP36,VSIG4,HPSE2,HMGCL,SHISA6,RAB41,IGSF1,IL6ST,INPP5B,NME9,ITGA7,JAK1,KCNA1,GPR62,KCNJ10,PAXBP1,MAT2A,MBD1,SYT9,MDM4,MEIS2,KCTD6,MMP16,MOG,ADAM22,BCO1,MSR1,NRBP2,NCAM1,SLCO1C1,NOVA2,OGG1,OMG,PBX1,PCDHGC3,PCMT1,CDK18,PDE4A,PDYN,PFKFB3,FTO,SEPT4,LRRN3,RASGEF1B,PKN2,MAPK10,HYDIN,GDPD2,PLPPR1,PXK,ZSCAN32,NKAIN1,MARCH1,DPF2,RFX5,SEC61A2,SETD5,ALG9,GSTCD,WLS,TRAPPC13,SEMA6D,ATXN2,TNFRSF19,ASIC4,CASC3,MRAS,ITSN1,SYBU,ZNF365,SMTN,FAM214B,ARHGEF40,CCDC88A,SCMH1,SMARCA4,LIMCH1,SNAP25,SNRPN,TRERF1,SP2,TEX2,C11orf87,CLSTN2,COLGALT2,NXT2,SEPT3,NSFL1C,ARHGEF9,SYN2,COBL,KAZN,ROBO3,CAMTA1,TMEM136,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,PCDHGA1,USP32P1,GALNT17,LRRC8A,PRRT1,TPM3,PRMT8,TRIO,RUNDC3B,RUSC1,SSBP2,HSPBP1,SLC35A4,LAT2,SF1,ZIC2,ZIC3,ZNF17,SLC26A10,CELF4,ZBTB38,FTSJ1,SMARCAD1,MEIS3,RNF103,CIAPIN1,FIP1L1,UBE3B,PHTF2,CASC15,RNF170,SSPN,DPF3" MicroRNA hsa-miR-26b*:mirSVR_highEffct hsa-miR-26b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-99 7.95E-96 8.55E-99 7.87E-98 290 1356 "KCNH8,NBAT1,ACTN2,XKR4,NDRG3,FMNL2,KLHL32,ADCY8,ADD2,AXIN2,BRAP,BEND6,CC2D2A,SPOP,OGT,LRCH2,EP400,CCDC146,PPFIA1,PKP4,GPAM,ALS2,DDO,TNRC6C,API5,SHTN1,ZFYVE28,ARHGAP5,ASPH,NCOA1,RASL11B,SLC4A4,EIF4G3,ATP1B3,ADGRB3,BBS2,BCL2L2,NRP2,CDK5R1,FUBP1,LINC00906,SCAPER,CASTOR3,C5,CA8,CALM1,SYT6,VSTM2A,RUNX1T1,CERS5,MTMR7,CD38,LRBA,CDH18,NOG,PLEKHB1,CASC2,CNOT8,NDST3,SLIT2,CLU,CLTC,FHL5,IQCK,ARMC8,ZNF521,NECTIN3,CLIP3,SNCAIP,TENM4,CSF2RA,ARHGEF10,APPL1,PHF14,GREB1,NRSN1,EDRF1,CX3CR1,ECE2,BOC,DOCK4,GAPVD1,TMEM170A,SPOCK2,ZBTB24,HEPH,FBXL5,CEP170,GSDME,PDCD6IP,DTNA,HIPK3,KLHL5,OPTN,YAF2,FAM13A,ELAVL2,CALCRL,EMX2,EPB41L1,LRRC23,EPHB1,GPHN,ADGRV1,ABCA8,WAC,CACNG2,ACSL4,SCML2,CEP78,FDFT1,FGF1,OLFM1,SUCO,CAP2,RGPD5,SGIP1,NOP56,WDR83,STAMBP,NRG3,ABLIM2,SDCBP2,ZMAT1,STAG2,GABRA1,GABRA5,CAB39,FAM120B,NCKAP1,ACSS1,KIAA1841,TUBGCP4,WASHC2A,PPARGC1A,COPS8,GLYR1,GLS,PCDH11X,CBX1,GNAS,GPD2,PRUNE2,GPM6A,TDRKH,MCHR1,NUDT21,GRM7,ADAMTS6,MAEL,NXPH2,TCEAL6,SMAP1,LRRCC1,NME9,KCNB1,KCND2,KCNN3,KIF5C,KLRC2,IPO5,STMN1,LOC100128239,MAP4,SYT9,LDLRAD3,MDM4,MEIS1,SRSF12,AFDN,MMP16,CTNNA3,MTTP,RSPO2,NF1,OTOGL,NFE2L2,NODAL,NOVA1,NPTX2,CLEC9A,OGG1,LOC100128398,GLIPR1L2,PAK3,PCDH9,PCSK5,ZNF655,FAM216A,PRRX1,SLC36A4,PPP2R5E,PPP3CB,MAPK9,MAPK10,GRAMD1C,GDPD2,MDGA2,CNTLN,ANKHD1,PTPRG,ACSM5,RAD51D,OXR1,ZMAT4,FIGN,SEC61A2,RIC8B,NUDT11,ZFHX4,GSTCD,ROM1,ATP8B4,GLDN,ADAL,ACER3,LRRK2,LGR4,SEMA6D,FAM19A1,SH3GL3,ARX,FNDC3A,FHOD3,R3HDM2,SYBU,NLGN1,NUBPL,PAAF1,FAM214B,KANSL3,ATF7IP,RCOR3,ANKRD36,SNRPN,TNIK,ZSWIM8,NMNAT2,ZC3H13,NPAS3,C11orf87,TAB2,ZC4H2,ZSCAN29,NEK4,SEPT8,FGD4,ARHGEF9,PLCB1,ANKRD28,TBCEL,FBXW11,ZEB1,CLASP1,SYNE1,CYB561A3,ZFP91,ERCC6L2,TMOD1,KCTD2,TPM1,NPL,ZNF384,SYNPO2,SMUG1,ZNF610,CADM1,UBE2H,PITPNB,P2RY12,RICTOR,SF1,ZBTB14,ZNF19,ZNF540,CELF4,TMEM237,ZNF184,PLPPR5,SMARCAD1,STOX2,PRDM10,LMAN2L,PCDH15,NAV3,FIP1L1,RGS7BP,UBE3B,SNX14,SLC4A10" MicroRNA hsa-miR-4296:mirSVR_lowEffct hsa-miR-4296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-99 8.17E-96 8.78E-99 8.09E-98 291 1365 "CPNE2,RALGAPA1,EMILIN3,FAM43B,FMNL2,GALNT16,DSCAML1,SLITRK1,ADORA1,ADORA2A,ADORA3,GPR158,KCTD16,WDR35,PCDH10,MRTFA,KIF6,LRFN1,ZFAT,ANK3,CNIH2,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APBB1,KIAA1614,SEMA4G,MADD,DYNLL1,ATM,TTLL9,ADGRB2,BTK,IL33,KALRN,CAMK2D,TRIM41,RHBDL1,DGKI,ZMYM4,MAGI1,TIGD7,NUMBL,SYNPR,NRXN3,KIAA1549L,NMT2,CLTC,QKI,CNTFR,IQCK,SMARCAL1,ZFP28,CREM,GDA,CLIP3,TRIM69,CSF1,RGS6,ATRNL1,SDC3,GREB1,ARHGEF4,CFAP61,NRSN1,ECE2,BOC,MYADM,ZNF337,IP6K1,DGCR5,ZEB2,HEPH,TIAM2,FBXL5,KIAA0753,SMG7,CD99L2,GNE,ARRDC4,TOM1,EDN1,EDNRB,CACNG7,YAF2,PHF20L1,APH1A,EBI3,EGFR,SORBS3,IRAK4,ELAVL4,MRNIP,DCTN4,EMX2,EPB41L2,EPHB1,CEP85L,SPEG,VPS26C,SIRPB1,EYA1,EZH1,REEP2,ZSCAN30,KAT8,FGF1,AMOTL2,MEX3B,IP6K2,FLT1,NOP56,DPYSL4,CINP,CELF1,KBTBD12,NEURL4,GABRA1,BRPF3,ALDH1L1,TUBGCP4,KIRREL3,TTBK1,ZNF638,MAP7D2,POLL,GNAS,PRUNE2,STON1,MCHR1,GRID1,GRM1,RNF165,FAM107A,ADAMTS6,SCRG1,HMGCL,HNF4G,TLX1,OPALIN,DHX35,HSD17B1,CELF5,MYLK2,LRRC25,USP54,IL11RA,INSM1,C2CD4C,SLC35G1,KCNH2,KCNMA1,LIFR,ZFYVE27,MARK1,MBD1,MBNL1,MBP,SRSF12,KITLG,MTTP,MYO5A,MYO7A,NCAM1,NUCB1,OPCML,CLDN11,OXTR,P2RY1,CDK18,NALCN,PIK3CD,FAM218A,CCSER2,PLCB2,MAPKAP1,PRRX1,SPATA6,FA2H,FAT3,POLR2F,PPARA,PRODH,MASP1,RELN,SAMD9,SIDT1,WDR25,FAM120C,ZSCAN2,RALGDS,NWD1,RASGRF1,GTDC1,SEC61A2,RAVER2,CARF,ROBO2,CCDC25,SNX22,SGSM1,TCP11L1,MAP6D1,HSD11B1L,ST6GALNAC6,KCNIP3,WLS,RYR3,LRFN5,ASIC4,SELL,GALNT10,STUM,COPZ1,RASA3,KIF21A,FAM102A,SHMT2,SLC1A3,LIMS2,KANSL3,PKNOX2,SLC6A8,SLC6A9,EFHD1,SLC20A2,LGI3,SMARCE1,RIMS1,KIF13A,SNRPN,FAM219A,IQSEC2,CLSTN2,SMOC1,ZC4H2,SSPO,MAPK8IP3,SEPT3,GSE1,JMJD6,ARC,COBL,TACC1,MLST8,IQCE,TBX15,CLASP1,SZT2,WDR7,SYNE1,CYB561A3,GALNT17,ERCC6L2,RIMBP2,TNFRSF1B,CABIN1,TPM4,WBP2,PRMT8,SMUG1,TRO,RUSC1,SSBP2,UBE3A,UBTF,OSBP2,ZNF709,VAV2,VLDLR,NSD2,GUSBP1,ZIC2,KCNT2,TRIM9,ZNF70,PLPP4,GPR158-AS1,NDRG4,ZBTB38,AMZ1,DPYSL5,PCBP1-AS1,DNALI1,PRDM10,WIPF2,RGS7BP,TMEM63C,CERS6,ZNF248,RNF170,JPH3" MicroRNA hsa-miR-675*:mirSVR_lowEffct hsa-miR-675*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-99 9.15E-96 9.82E-99 9.04E-98 260 1100 "ACLY,KDM5D,GPRIN1,GALNT16,HACE1,TAOK1,LRRC7,SMIM17,ALCAM,EP400,MAP4K3,PHF12,ANXA7,APBB2,ALS2,SHROOM2,PPP4R4,NCOA1,EIF4G3,MTMR9,B3GALT2,ADGRB2,C5,CALB1,KALRN,CAMK2D,ISPD,CD86,CD38,CIART,CASC2,NRXN1,HECTD1,PCYT1B,BTF3L4,AHCTF1,MFSD4A,GDA,ABCG1,SNCAIP,NCAN,PDE4DIP,PLCXD3,CFAP61,CTNND2,KIAA0408,ARHGAP24,EARS2,ZNF337,LIN54,PABPC5,DCC,DNAJC6,MYEF2,WDR20,DMD,DNAH9,SLC12A6,CASP8AP2,DTNA,AASDH,ANKRD46,MBNL2,EIF4G2,ELAVL2,PLEKHA1,EML1,EMX2,RABEPK,SRRM1,FCGR1A,CEP78,FCGR3A,SEC24B,KIAA1109,FGFR3,POLK,SCARA3,SEMA4D,FLT1,PSD2,SLC37A3,PDLIM5,ATP6V1H,DKK3,GABRA5,CHL1,NCKAP1,DISC1,LRRC37A6P,ALDH1L1,MSTN,CYP46A1,GFAP,GLRB,TOX3,PCDH11X,KIAA1958,KDM2B,WDFY3-AS2,GPD2,GRID1,GRM7,GRM8,BTN2A1,FAM19A2,SLC2A6,MAP4K5,UBE2QL1,ZHX1,HMGB1,GABARAPL2,ZDHHC15,ZNF546,IGFBP1,LIX1,INPP5B,INSM1,LRRTM3,SLC35G1,OLFM3,KCND2,KCNJ3,KCNK2,STXBP5,INSYN2,HECTD2,PIK3AP1,AQP11,MATN3,SYT9,MEF2C,KCTD6,MGAT3,MN1,MOBP,ERICH3,SAMD5,SCG3,MYCN,MYO9A,BEX5,NEK1,NEUROD1,NF1,NHLH1,NPTX2,HCN1,NTRK3,OPA1,LOC100128398,P2RX7,CNTN3,ETFRF1,PDE3B,NALCN,PIK3C2A,ZNF655,PLIN1,PMP2,STRN3,LRP12,EXOSC10,POU3F2,TATDN3,NKAIN4,RASGEF1B,HYDIN,PROX1,MASP1,BCAS3,QRICH1,PTAFR,ANKHD1,PTPRB,PTPRD,PTPRE,PTPRG,RASGRF1,RFX5,SLC25A36,ROBO1,ROBO2,LGR4,PTGR2,SOX8,CLIP1,RYR3,NCBP3,CCDC112,SEMA6D,ATXN1,LRRTM4,SOX6,GALNT10,SUPT20H,SH3BGR,ITSN1,FNDC3A,FHOD3,R3HDM2,SLITRK3,DZIP1,PAAF1,WDR37,ZNF365,SLC1A3,RUFY2,SLC6A11,SLC12A2,LGI3,SLC22A4,RIMS1,MAPKBP1,CABCOCO1,ZNF415,PDZRN3,SON,ZSWIM8,MYCBP2,RBM26,LHPP,COBL,ANO4,EHBP1,WDR7,SYNE1,PCDHB7,HIF3A,TGFBR3,TJP1,BHLHB9,TMPO,ANO5,SSBP2,TUBB1,SLAIN1,USP1,VLDLR,VSNL1,NSD2,XRCC4,PCDH20,ZNF24,FMN2,FSTL5,ANKS1B,CA10,EMSY,CADM2,PRDM2,RNF103,C12orf4,PDSS2,RGS7BP,DNAH10,FZD3,JMJD1C,RNF170,MSRB3" MicroRNA hsa-miR-3187:mirSVR_lowEffct hsa-miR-3187:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.68E-99 9.42E-96 1.01E-98 9.30E-98 281 1278 "KCNH8,SYN3,NCKAP5,NDRG3,TMEM132B,ADD2,PLEKHH1,KIDINS220,BEND6,RTL9,C1QTNF3,ALCAM,CARNS1,MRTFA,TRMT9B,AMPD2,DPP10,APBB2,PPFIA3,LINC00173,ASPH,DACT3,ATP2B1,ALDH7A1,N4BP2L1,BCHE,MMD2,BTRC,CA8,CACNB2,CAPN3,RHBDL1,SPAG9,CBR1,CLDN10,CERS5,CCNH,CD86,MAGI1,CCPG1,ARHGAP22,EPS15L1,NRXN3,PLAA,KIAA1549L,TJP2,MAP4K4,PCYT1B,ARMC8,AKAP5,ABI3BP,HS3ST5,CHD1L,SNCAIP,MICAL2,CSNK1G3,ATRNL1,PDE4DIP,DZIP3,PPP1R16B,KIAA0040,NRSN1,ECE2,NOS1AP,EARS2,TBC1D5,MATR3,IP6K1,ARMCX4,ARMCX2,DGCR5,KIAA0319,DLG3,HS3ST4,CDON,CPEB2,DRD1,DTNB,MAMLD1,DNAJB6,DNM1L,ABCC9,SGK2,SYT15,CNNM1,TMTC1,RBM12,FAM13A,EIF5,LRRC17,RABEPK,NCALD,DNAJC27,REEP2,WAC,FCGRT,FDFT1,FHL1,MEX3B,HPCAL4,FOXG1,IP6K2,DACH2,ABLIM2,TVP23A,HRASLS5,JPH4,GALR1,SIGLEC8,GATM,ADAM28,RND1,GLDC,RAB30,GNAO1,STMN2,GRM7,RNF165,TMEM25,KAT7,RNFT2,MAP4K5,ATOH8,TMEM179,MAEL,C1orf94,AGBL5,TLX1,HTR2A,DOCK7,SCIN,INSM1,TUBB2B,KCNK1,KCNMA1,LAMP2,CAMK2N2,STMN1,INSYN2,LIFR,LMO2,SYTL4,HECTD2,MAN2A2,MAPT,AFF1,MMP16,GIT1,DBNL,COMMD5,RTL5,ZNF862,P2RY13,NCAM1,NPR2,OPA1,GPR137C,PCDH9,PDE1C,PDE1B,PDPK1,GPR173,GNG2,GDAP1L1,NOMO2,FXYD1,TRHDE,STRN3,ING3,POU6F1,MED1,PRKAB2,FITM2,DIRAS2,PRPH,RELN,DEF8,CNTLN,PLPPR1,BDNF-AS,PTK2,DKFZp779M0652,PTPRE,PTPRG,PTPRO,FAM120C,PTX3,NKAIN1,ZNF615,TUG1,PPP2R3C,USP47,ZNF793,RALGDS,ATG16L1,NWD1,DBX2,MORC4,PBRM1,CCDC82,ROBO1,ROBO2,TMEM206,MRAP2,NEK11,FBXW7,KIAA0895L,ATAT1,KCNIP3,CLIP1,RMI1,MIR124-2HG,SATB1,SCN2A,RASA3,SCG5,SH3GL3,PPM1E,NTNG1,FBXO11,FNDC3A,ST3GAL3,DZIP1,ABLIM3,SMTN,EFHD1,COA1,SMARCD3,RIMS1,FAIM2,MYO16,PDZD2,WDTC1,SOX5,KIF21B,ZSWIM8,KDM4C,COLGALT2,CEP68,KANK1,KLHL7,SYT11,PRRC2C,ABCC8,C3orf70,SYT4,UNC5D,SIN3B,DMXL2,TPCN2,SYNE1,PCDHB10,PCDHB3,FRYL,AHCYL2,CRB1,BHLHB9,ERCC6L2,RIMBP2,TNR,ZNF346,ELP5,RUSC1,ANO5,TTC3,FLRT1,LMF1,RICTOR,SLC13A3,ZNF70,ZFAND5,SYNC,EMSY,GDPD5,LINC00632,GOPC,DNAH10,VANGL2,SOCS4,LAS1L,FAM198A" MicroRNA hsa-miR-493-5p:TargetScan hsa-miR-493-5p TargetScan 1.78E-99 1.00E-95 1.07E-98 9.86E-98 190 580 "ABR,FMNL2,ADARB2,GRAMD1B,RNF150,HECW2,OSBPL6,PITPNM2,ANK2,MAP4K3,PHF12,DGKD,MADD,ARHGAP5,MARK4,NCOA1,RASL11B,ATP2A2,ADAM23,BCL7A,FUBP1,MTMR3,BSN,CACNB2,MAP7,RUNX1T1,ENTPD6,DGKI,CDH2,LRWD1,GPR37L1,RAB3C,NRXN3,NIPBL,AKAP6,NRG2,NSL1,AKAP12,LRIG1,PITPNM3,CTNND1,CTNND2,KIAA0408,FRMPD4,RIMS3,SCRN1,BRINP1,JAKMIP2,ELMO1,HP1BP3,AK5,DLG2,GRIN3A,DMD,NR1D2,DNM1L,RASGRP1,EFNA3,RBM12,EGFR,MBNL2,ABI2,RGS17,SCML2,FOXO3,PSD2,FAM49B,CAMKK2,NSG2,FUT9,MPP6,GABRA1,GABRA5,GABRB1,GABRG2,GAD1,GART,CPLX2,AHDC1,GFRA2,MALT1,GLUL,KDM2B,INSM2,NUDT21,GRM5,RASSF8,HMGCR,NEGR1,AGFG1,HTR2A,MYLK2,IGSF1,LRRTM3,METTL21A,KCND3,KCNJ10,KCNK1,KIF2A,L1CAM,ARHGAP12,NCOA7,LSAMP,MARK1,MEF2C,MGAT3,SCAMP5,GIT1,OPCML,PBX1,PDE1C,PDE4D,PDPK1,NLGN3,PIK3R1,KCTD15,FTO,PCDH18,PURG,LRP12,FAT3,MED1,PPP2R2C,PPP2R5C,PPP3CA,PPP3CB,PKIA,CNNM2,PTCH1,PTPRD,RAD52,RDX,RGS10,ROBO2,RPE,RXRA,SALL1,CSRNP3,ATXN2,FNIP1,GALNT10,NLGN1,CLSTN1,LRRC55,ELMO2,CXXC4,IGSF9B,LIMCH1,MBD5,MYT1L,KDM3A,NMNAT2,MYCBP2,KIF1B,RBM26,NPAS3,LMO3,LARP4,DIP2A,NECAB1,FGD4,ANKRD28,ANKRD12,KAZN,CAMSAP2,FBXW11,ANO4,CLASP1,FAM189A1,PSD3,PUM2,CRTC1,GPRIN3,HHIP,NR2C2,RFTN2,OSBP2,FLRT2,REEP1,EML6,CADM2,EVI5,NAV2,KCNAB1,FZD3,KAT6A,HNRNPA3,FXR1,NETO2,NETO1" MicroRNA hsa-miR-9:mirSVR_highEffct hsa-miR-9:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.84E-99 1.03E-95 1.10E-98 1.02E-97 293 1384 "ACADM,ARID1A,XKR4,ADD3,SLC12A5,PLEKHH1,PWWP2A,PTCHD1,SLC44A5,HECW2,KLHL13,OSBPL6,CC2D2A,ALAD,ALCAM,UNC79,ANK2,PKP4,PARG,APBA2,GPAM,TNRC6C,SHTN1,ZBTB10,CCAR2,ATP2B3,DPY19L3,TTLL9,MPDZ,NRP2,KSR1,SYNJ1,MTMR2,IL33,CACNB2,CALB2,KALRN,PTBP2,MAP7,ZNF501,DGKI,LRBA,ARHGEF2,CDH8,LRRFIP1,LGI1,LOC730101,MAGI1,CDO1,JAM2,NDST3,PLAA,FAM19A5,AKAP7,COL9A1,TBPL1,BAG4,MYRIP,NRG2,SEC31B,CLOCK,HAPLN1,GDA,CSF1,CSF2RA,ARHGEF10,MICAL2,VCAN,SOCS5,GREB1,NRSN1,CCDC144A,CYBB,KATNAL2,RIPOR2,ARHGAP24,MATR3,TOMM20,ARMCX2,JAKMIP2,RHOBTB1,SACS,FAM107B,EXOG,DMD,HS3ST2,USP3,CPEB2,ABI1,PDCD6IP,DYRK1A,E2F6,AASDH,CNNM1,RASGRP1,FRY,OPTN,MBNL2,ABI2,AASS,TENM1,C8orf37,DCTN4,EPB41,KCNMB2,TLR7,ABCA8,CHST15,TESK2,GTF2IRD2,OLFM1,FGF12,FGFR1,FOXG1,ZBED3,UFM1,PDLIM5,TPK1,STAU2,ADGRA1,DKK3,GAD1,ARPP21,MTHFD2,C15orf41,PCDH17,C1QL1,LYVE1,SPIN1,GLS,TNRC6A,CBX1,GSTT2,ADAMTS6,HPS5,MIER3,ACOT7,ZNF491,C9orf129,FAAP20,IRF8,IDH3A,ZIC5,DOCK7,LRRCC1,USP54,IL12A,JAK2,KCNMA1,KCNN2,KCNN3,LMO2,NCOA7,LYPLAL1,MBNL1,MDM4,MEF2C,ERICH3,MSI1,NRBP2,NAP1L1,NCAM1,NEK1,NFE2L2,NRCAM,GPR88,CHAMP1,OXTR,P2RY1,GPR137C,CNTN3,PCSK2,PDE4D,PIRT,GPR85,BEST3,GDAP1L1,PIK3R1,CCSER2,PLCL1,PLP1,SLC25A23,PMP22,PRRX1,SEPT4,POU3F2,PPP2R5C,GRAMD1C,MDGA2,CNTLN,UHRF1BP1,TMEM260,PTPRB,FAM120C,ZSCAN2,TUG1,ZNF793,RASGRF2,RADX,HKR1,RDX,RET,ERI2,MORC4,PBRM1,ZNF532,RPE65,RPL15,MCMBP,GLDN,SGSM1,LRRK2,CNTNAP3,AP1AR,LRRTM4,NLGN4Y,KIF21A,ARX,CPEB3,DOCK10,NTNG1,AMBRA1,NLGN1,SLC8A1,CCDC88A,SLC12A2,SLC14A1,BTBD7,SLC20A2,ATF7IP,CPEB4,ZFP1,OGDHL,LIMCH1,SNCA,CMTR2,UNC80,WDTC1,TRERF1,KIF1B,RBM26,TAB2,POGZ,SAMSN1,LRRC4,SS18,FGD4,ARHGEF9,MTCL1,DDHD2,ANO4,VWA3A,DOCK9,SLC19A3,USP32P1,FRYL,SIK3,SIRT1,AP4E1,GZF1,DDHD1,ERCC6L2,HEY2,NPL,PPIL6,UBE3A,UGT8,BEST1,VSNL1,ZBTB14,ZNF19,TRIM9,SLC26A10,TCEAL7,ZBTB38,EML6,PLPPR5,MFF,DNALI1,ADAMTS9,PCDH15,KCNAB1,ITM2C,HRASLS,FAM13C,SMIM8,PHTF2,CASC15,ACTR3B,ADAMTSL3,NHSL1,FRMD6,DPF3" MicroRNA hsa-miR-3168:mirSVR_highEffct hsa-miR-3168:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.23E-99 1.25E-95 1.34E-98 1.23E-97 244 972 "CLK4,NCKAP5,ARID1A,DSCAML1,ADCY8,GALNT13,ADD3,SLC44A5,INTS2,KCTD16,OSBPL1A,ALCAM,ARHGAP20,PCDH10,CCDC146,GPAM,DDO,LGR5,ASPH,ZSCAN18,EIF4G3,ATP2A2,B3GALT2,AZGP1,CDK5R1,DST,SCAPER,JAZF1,CA8,CALB1,KALRN,CAMK2D,CANX,VSTM2A,CH25H,GPR37L1,CHGB,CHM,CHN2,B4GALT6,KMT2C,TPP1,TJP2,ABCG2,FAM149A,SLC4A7,ABI3BP,RTTN,ANKRD44,ATRNL1,NCAN,SOCS5,PDE4DIP,CST3,FAM169A,APPL1,CFAP61,ZSCAN23,DCAF4,EDRF1,CX3CR1,ARHGAP32,DCAF8,LONRF1,DNAJC6,MYEF2,MAGI2,PLPPR4,SPOCK3,NTM,G3BP2,WDR20,DLG2,EXOG,RAB39B,CDON,CASP8AP2,GNE,WDPCP,RASGRP1,GPR61,PHF20L1,PLEKHA1,EPB41L2,SRRM1,RTN3,ZNF589,FER,FGF11,UBE2E3,SYNCRIP,FLT1,SGIP1,PDLIM5,CELF1,CGREF1,STAU2,ZNF512,STAG2,MEGF10,GABRA3,GABRB1,ZMYND11,SALL3,ZNF559,DNER,GGTA1P,GHR,PPARGC1A,HPGDS,MSL3,PCDH11X,KDM2B,PRUNE2,FUT10,EML4,GPR37,CNTRL,GRIA4,NR3C1,GRM3,GRM8,CIT,FAM19A2,UBE2QL1,TOX2,ZHX1,MIER3,ELOVL5,HNMT,CFAP126,IRF8,MSL1,LRRCC1,PLD5,IL11RA,INSM1,LRRTM3,KCNK1,KCNN2,MAP4,MBNL1,TM6SF1,MEIS1,ZNF680,TAGLN3,MYCN,MYO9A,PABPC1L2A,NCAM1,NF1,SLC11A2,NRCAM,NTRK3,GPR88,OPHN1,OXTR,PDYN,BEST3,OLA1,ZNF655,XRN1,GPSM2,JAKMIP1,HMGCLL1,DRAM2,TMEM235,MAPK8,GRAMD1C,GDPD1,SNRK,TMEM260,PTPRE,RAP1GDS1,ARID4A,RBBP6,ZYG11B,GTDC1,RGS12,RPRD1A,TMLHE,EXD2,ROBO2,YY1AP1,CCDC102B,NEK11,ABCA11P,KCNIP1,TRAPPC13,AP1AR,FAM19A1,SEC14L1,KIF27,TRA2B,SEC31A,ABLIM3,SLC6A1,SCN3B,DOK5,SP4,ERC1,RBM26,LMO3,ATP10B,NXT2,FGD4,SYNE2,VPS13A,PLCB1,FAM208A,ADGRL3,NAT16,FRYL,AHCYL2,CRB1,LEFTY2,ZMAT3,SLC44A1,TK2,BHLHB9,TMOD1,TMPO,TPM1,TRIO,DCBLD1,CLHC1,USP1,CCDC14,ZNF781,CFAP52,REEP1,FSTL5,ZNF225,EMSY,MDH1B,PCDH15,WIPF2,FAM13C,DOCK8,RTN4,KAT6A,IFT88,NETO1,CBLN2" MicroRNA hsa-miR-4325:mirSVR_highEffct hsa-miR-4325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.26E-99 1.27E-95 1.36E-98 1.25E-97 238 925 "CSMD2,TMCC3,SORCS1,UNC5A,PWWP2A,KIAA1211,INTS2,PCDH19,OSBPL6,TXNDC16,ABCD2,MARCH4,OGT,DPP10,PPFIA2,PPFIA1,SHTN1,TMEM263,ARNTL,ASCL1,DDX3Y,ALDH7A1,ADAM23,RGS9,BCL7A,HCN2,SYNJ1,OSGIN2,BSN,CACNB4,KALRN,CANX,VSTM2A,CAST,SPAG9,PRC1,CDH2,LOC730101,NOG,CHM,SYNPR,RAB33A,NRXN3,CLTC,HECTD1,BTF3L4,MYRIP,CSF1,TENM4,OSBPL3,SOCS5,PDE4DIP,CTH,USP6NL,NOS1AP,RIPOR2,TMEM170A,DAPK1,DBI,DCC,PITPNC1,DNAJC6,ZNF804A,RHOBTB1,KBTBD11,DMPK,NR1D2,CPEB2,DSCAM,DYRK1A,FAM135B,CNNM1,FRY,PHF20L1,EIF4G2,PCOLCE2,TMEM35A,EML1,VPS13B,RCAN2,SRRM1,EXTL2,F3,CLVS1,EFEMP1,DLC1,SEC24B,POLR1B,PRKAG2,POLK,UBE2E3,JKAMP,SORBS1,NPTN,ATP6V1H,ZNF605,KHDRBS3,ST6GALNAC3,NSG1,OGA,GAA,GABRA2,IQGAP2,GATM,ADAM28,LYVE1,GLS,POLL,PCLO,ADAMTS8,GRM1,PRDM5,FAM19A2,LINC01551,FAM222A,HNRNPK,ZDHHC15,HSP90AA1,MSL1,DIPK1A,SLC35G1,KCNA1,KCND2,KCNMA1,KIF5A,KLRC2,MAP4,MARK1,MDM4,MN1,MOBP,ADAM22,MSRA,NEXMIF,NBL1,NEFH,NEUROD1,NF1,NFIA,NPTX2,NRCAM,NTRK2,NTRK3,OXTR,P2RY1,GPR137C,PAK3,PDGFRA,GPR85,PENK,PIK3R1,HMGCLL1,ANKRD16,STRN3,MED1,PPP3CA,PPP3CB,PPP3CC,CEP41,PKN2,BCAS3,GON4L,PEX5,STRC,TMEM255A,SH3TC2,ZNF493,DPF2,FIGN,RGS3,ZFHX4,LGI2,SETD5,RPL15,FBXW7,GLDN,LRRK2,SYNDIG1,ABCA11P,RTN1,TRAPPC13,AP1AR,SCN3A,FNIP1,SOX6,SELL,CHD9,ZNF430,RAB3GAP1,ANKRD36,SNAP25,SNRPN,DOP1A,PDZD2,MYCBP2,C11orf87,TROVE2,ITPRID2,SSTR2,SEPT8,CEP68,DIP2A,NECAB1,NUDT10,SYPL1,SYT4,TCF4,SYNE1,DOCK9,PCDHB3,PUM2,AP4E1,TLR4,TMOD1,RBFOX2,SYNPO2,TRO,TRPS1,TTTY15,SGK3,UBE3A,AMOT,PLEKHH2,PCDH20,ZIC1,KCNT2,FMN2,MKRN3,ZXDA,PRDM8,SLC17A6,FZD3,DOCK8,PHTF2,JMJD1C,NETO1,SLC4A10,SENP7" MicroRNA hsa-miR-532-5p:mirSVR_highEffct hsa-miR-532-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.26E-99 1.27E-95 1.36E-98 1.25E-97 251 1028 "ACADM,C3orf14,XKR4,KLHL32,SORCS1,PWWP2A,KIAA1211,ADRA1B,PCDH19,AK2,ABCD2,LRCH2,ANK3,USP28,PPFIA1,ALS2,CACHD1,BCAS1,CDC14B,BACH1,DCAF5,KSR1,DST,SYNJ1,ARHGEF7,CAMK2G,CAPN3,CAST,KRIT1,CDC42,ZMYM4,LGI1,CDO1,DLGAP1,CASC2,SYNPR,IGFBP7-AS1,TJP2,QKI,ARMC8,SLC25A27,SUMF2,RTTN,ACBD5,HS3ST5,CHD1L,CLOCK,HAPLN1,FEZ2,SLITRK5,CTNND2,NRSN1,ARHGAP24,TBC1D5,DCC,HP1BP3,PLPPR4,USP3,DPP6,PDCD6IP,DSCAM,DTNB,RASGRP1,KMT5B,AASS,EML1,TUBD1,ZNF549,DNAJC27,F5,F8,ZIC4,RACK1,SEC24B,FGF11,SUCO,SEC23B,CAP2,RGPD5,NBEA,PDLIM5,ATP2C1,NSG1,CHL1,ZMYND11,IGSF5,MSTN,ADAM28,COPS8,DBF4,ZNF638,GNAS,FUT10,STON1,GRIA2,RNF165,ZBTB49,MFSD2A,FAM222A,FRMD5,HPSE2,HNRNPK,C9orf129,NEGR1,NKD1,RBPJ,IL6ST,KCNA1,CLVS2,IPO5,KTN1,HECTD2,SMAD1,MAP2,MAP4,LRP1B,MEIS1,SRSF12,POC1B,XRRA1,ADAM22,ZNF92,MTTP,NAP1L1,P2RY13,NCF2,NDP,NEK1,NF1,NOVA1,SLC11A2,NRCAM,HCN1,OCRL,P2RY1,GPR137C,PAH,SNTG1,PCDH9,PCSK1,PRTG,PENK,PFKFB2,OLA1,NALCN,PIK3C2A,ANLN,CCSER2,GPSM2,PURG,TRHDE,MAPKAP1,SCHIP1,ING3,EPB41L4B,MED1,MINDY2,PRKACB,PKN2,VPS13C,GON4L,CNTLN,TMEM260,PTPRB,RAD52,OXR1,RADX,GTDC1,RFX4,RFX5,NUDT11,PBRM1,TMLHE,RAVER2,GSTCD,ROBO1,ELP2,CCDC102B,RPE65,SPIN3,ZC3H14,ABCA11P,TMEM156,LINC00461,SH3BGR,CPEB3,CHD9,SYBU,SEC31A,EPN2,SLC8A1,CCDC88A,BTBD7,CXXC4,RCOR3,TTC17,PALLD,SON,PDZD2,TNIK,ENKUR,KDM4C,ZNF423,ZC3H13,CDK19,NPAS3,C11orf87,TROVE2,ELOVL4,SEPT8,KLHL7,FGD4,JMJD6,VAMP1,WASHC4,RALYL,PCDHB10,NSD1,PUM2,FRYL,TIAM1,TJP1,TLL2,BHLHB9,ZFP91,SYNPO2,PDSS1,TTPA,RPL7L1,AMOT,GUSBP1,XPO1,PCDH20,GPR158-AS1,LYPD6,FSTL5,SPIRE1,SMARCAD1,UPF3A,SLC30A4,PRDM10,PCDH15,FAM47E,WNK3,C12orf4,PDSS2,RGS7BP,FZD3,DOCK8,PAK5,SLC4A10" MicroRNA hsa-miR-10b:mirSVR_lowEffct hsa-miR-10b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.27E-99 1.28E-95 1.36E-98 1.25E-97 301 1457 "NBAT1,CSMD2,FMNL2,TMEM132B,SLC12A5,SORCS1,GRAMD1B,USP31,NLGN4X,ZNF608,MTUS1,PCDH19,KCTD16,DISP3,TAOK1,CEP126,AMPD2,ANK1,ANK3,FGD2,LCORL,CDK10,SFMBT2,SPTBN4,PLA2G4C,CDK13,BRINP2,DYNLL1,CHID1,SLC4A4,ALDH7A1,DPY19L3,BMPR1B,NAE1,LURAP1,CAMK2B,CAMK2D,CAMK2G,SPAG9,ZNF501,LRRFIP1,ZNF445,GPR37L1,NDST3,COG1,NMT2,FBXO7,TJP2,MAP4K4,NIPBL,CNGA3,ARMC8,SUMF2,LETMD1,TOGARAM2,HINFP,NCOR1,GDA,ABCG1,CS,LRIG1,FEZ1,CSNK1G3,VAC14-AS1,PDE4DIP,UBXN2A,EDRF1,HDAC4,DAPK1,ARMCX4,RUSC2,POM121,SRGAP3,WDR20,KBTBD11,GRIN3A,NYAP1,FAM57B,GNE,ECM2,DNAJB6,SNX29,FAM135B,FAM13A,GPR61,MBNL2,IRAK4,COPS4,MRNIP,C3orf18,DCTN4,COQ7,LRRC17,RABEPK,DENND4A,ZNF549,VPS26C,DLC1,PPP1R1B,GORAB,TMEM164,PRKAG2,SEMA4D,FLT1,ANKFY1,JKAMP,ERGIC3,CELF1,CGREF1,CHL1,GALNT15,GABRG1,RAPGEF6,ZNF559,ALDH1L1,WASHC2A,MMADHC,LYVE1,CRCP,SPIN1,MSL3,KCNMB4,ATF7,TMEM121B,GRIK3,GRIK4,GRM3,GRM7,GRM8,LINC01089,BTN2A1,BACH2,GABARAPL2,HNF4G,ZNF491,HNRNPK,NEGR1,OPALIN,HTR2A,ATCAY,FAM95B1,IDH3B,ITIH2,JAK1,CDH20,GPR62,KCNN2,STXBP5,INSYN2,HECTD2,FGFBP3,LSS,CLEC18A,ZFYVE27,MAP2,MAP4,MBP,BLOC1S2,MSR1,MYO6,MYO7A,NTRK2,NUCB2,CLDN11,ZDHHC22,PDE4A,PDGFRA,A2ML1,NLE1,FTO,PLP1,SMIM7,PLXNB3,SEPT4,MED1,GRAMD1C,PSD,GON4L,BDNF-AS,PTH1R,TMEM260,PTPRO,ZSCAN2,TTC13,CCDC40,ZNF493,ZDHHC14,DPF2,GTDC1,UBR7,KCTD17,MRPS18A,CCDC82,ZNF532,CARF,KIRREL1,RPL15,ARMH4,UEVLD,MCMBP,ZNF568,ZNF331,FOXRED2,ATXN7,LRRTM4,TNFRSF19,IL17RB,SUPT20H,COPZ1,NLGN4Y,SGK1,ASAP3,FUZ,FBXO11,FNDC3A,ZNF365,URGCP,KANSL3,LRRC55,SEPHS1,RADIL,SLC12A2,SLC14A1,BTBD7,CPEB4,MAPKBP1,MBD5,SNRPN,TMCC1,RBM34,MYT1L,SOX3,BDP1,LHFPL4,KDM4C,ERC1,UNC5B,KIF1B,TSPYL2,SPART,LHPP,ERBIN,SEPT8,RGL1,KANK1,SEPT3,VPS13A,SYN2,ANKRD28,PJA1,DDHD2,FAM208A,UNC5D,TBCEL,IQCE,ACSL6,NEU4,DMXL2,SATB2,AKNA,ARHGEF12,TNS2,DICER1-AS1,AP4E1,TGFBR3,MTMR14,TLR4,TMOD1,TMPO,DAAM2,CSMD1,KAT6B,C9orf85,PRMT8,STXBP4,PPIL6,TSC1,OSBP2,FLRT2,ZNF709,VIPR2,WIPF1,CLDND1,CELF4,EML6,SPIRE1,ZFAND5,EMSY,CSDE1,LINC02210,TUBA1A,HPS4,FIP1L1,TRIM16L,PLSCR4,GOPC,SMIM8,TMEM63C,SSPN,CPNE4,SENP7" MicroRNA hsa-miR-3173:mirSVR_highEffct hsa-miR-3173:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-99 1.42E-95 1.51E-98 1.39E-97 260 1102 "TTYH1,ABAT,KCNH8,SYS1,ARID1A,ADARB2,TMCC3,ADD2,SORCS1,ADRA1B,KIAA1324,CC2D2A,SRPX,ZNF687,MYH7B,APAF1,SHTN1,SHROOM2,CDC14B,SPTBN4,ASPH,DACT3,TMEM108,ATP6V1G2,CFLAR,KSR1,CDK5R2,CACNA1E,KALRN,PTBP2,ARHGEF25,CBR1,USP6,INA,LGI1,MAGI1,TIGD7,CHN2,SYNPR,CLCN3,TPP1,SRP14-AS1,ARMC8,BTF3L4,CNRIP1,CS,VCAN,PDE4DIP,PHF14,ARHGEF4,PPP6R2,ARHGAP24,ZFYVE16,ZNF337,DAPK1,TOMM20,PABPC5,DCT,ZEB2,HP1BP3,CEP170,CCDC3,EXOG,RAB39B,DMD,CDON,DMTF1,CASP8AP2,ACOT8,DTNA,ANKRD46,FSD1L,CELSR3,PHF20L1,APH1A,RASGRP2,EPHB1,SIRPB1,EXTL2,EYA1,CLVS1,CACNG3,CORO2B,PRMT5,KAT8,FER,OLFM1,RGPD5,PSD2,NELFCD,POMT1,NRG3,FYB1,GAD2,GAP43,GATM,NEU3,GGTA1P,LYVE1,GLS,TNRC6A,GLUL,PCDH11X,RAB40B,GNAS,FUT10,TUBA1C,GRIA4,GRIK2,GRM2,MFSD2A,LINGO1,ADAMTS6,MAN1B1,SHISA6,MSL1,ZIC5,IGSF1,ITGAM,JAK1,KCNMA1,KCNQ3,TTYH2,LSS,MAG,ZFYVE27,MAOB,MATN2,TM6SF1,MEIS1,CCDC80,ADAM22,BCO1,RSPO2,NDUFA5,NEFH,NF1,SLCO1C1,ALDH1L2,CNOT4,NOVA1,NTRK2,NTRK3,NUMA1,GPR137C,PAK3,PBX1,OLA1,NALCN,ZNF655,PLCB2,SMOX,TRHDE,SPATA6,POU3F4,HYDIN,BCAS3,VPS13C,LRRC49,SIDT1,QRICH1,PTCH1,PTK2,TMEM260,PTPRB,PYGM,ZSCAN2,NKAIN1,MARCH1,RAD51D,ARID4A,ZYG11B,MORC4,SEC61A2,MYH14,GSTCD,YY1AP1,CCDC102B,FBXW7,BAALC,ZNF671,STK32B,MAP6D1,FAM192A,SEMA6D,LINC00461,SEC14L1,CASC3,CHD9,ZNF365,SLC1A7,PPP4R3A,PKNOX2,CCDC88A,SLC9A5,SMARCE1,ANKRD36,RIMS1,ANKFN1,PDZD2,TRERF1,SOX15,ZSWIM8,ZC3H13,KIF1B,IQSEC2,ZC4H2,SEPT8,TTBK2,VAMP1,ARHGEF9,DNAJC9,COBL,ANKRD28,TACR1,KAZN,ROBO3,UNC5D,EHBP1,RPGRIP1L,GPRIN3,FRYL,AP4E1,TGFBR3,SLC44A1,TMEM9,HEY1,BHLHB9,LRRC8A,TMOD1,TNR,TPM1,CDK20,NPL,TPM2,ZNF384,METTL3,PRMT8,RUNDC3B,RUSC1,HSPBP1,HEPACAM,CCDC136,TBC1D15,WIPF1,ZNF781,ZIC3,ZNF17,SLC26A10,MKRN3,CELF4,SMARCAD1,FIP1L1,LINC00632,WIPF2,ST7,MARCH8,KAT6A,PHTF2,NHSL1" MicroRNA hsa-miR-202*:mirSVR_lowEffct hsa-miR-202*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.96E-99 2.23E-95 2.37E-98 2.18E-97 294 1397 "ABAT,SYN3,NBAT1,XKR4,GALNT16,SLITRK1,SORCS1,PWWP2A,PTCHD1,MTUS1,WDR35,ZNF578,LRRC7,SPARCL1,ALCAM,CEP126,ARHGAP20,FAM135A,DPP10,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,API5,APP,PPP4R4,IGDCC4,ARNTL,STK33,ZBTB10,DDX3Y,SLC4A4,EIF4G3,ATP2A2,NOL4,ATP6V0A1,BCL7A,CDK5R1,FUBP1,JAZF1,NIPA1,RAB29,MYRF,KALRN,ISPD,MAP7,LGI1,DLGAP1,CHN2,SYNPR,PPT2,CLCN4,CNN3,AHCTF1,BAG4,ACBD5,SLC35F1,RBM39,HAPLN1,PDE4DIP,CST3,PLXNA4,SLITRK5,CTNND2,ST18,USP6NL,ECE2,CCDC144A,CYBB,GAPVD1,FRMPD4,IST1,AIF1L,GIT2,DNAL1,ZBTB24,HP1BP3,FBXO25,SMG7,SNAP91,FAM107B,GRIN3A,RAB39B,DRD1,DNAJB6,ATL1,KLHL5,RBM12,YAF2,PLEKHA1,EPHB1,CEP85L,VPS26C,DUSP27,AMZ2,CORO2B,FHL1,SCARA3,PCYOX1,SYNCRIP,EFCAB2,TACC2,TMEM107,SMC2,UFM1,GABRA1,TRAF3IP2,AHCYL1,BRPF3,ZNF234,DISC1,PPARGC1A,ZNF276,GLI2,TOX3,PCDH11X,ZNF782,GNG4,FERMT2,GOLGB1,NUDT21,GRIA1,GRIN1,GRM7,ATOH8,RASSF8,ZHX1,TNFAIP8L3,LINC01102,BACH2,VSIG4,HNMT,SCIN,ZNF385B,JAK2,SLC35G1,KCNA2,KCNK2,KLC1,INSYN2,LIG4,HECTD2,NCOA7,SMAD9,GPR155,MAP2,MAP6,MBP,CHIC1,TM6SF1,MEIS1,MEIS2,MID1,MMP16,MOBP,ZNF680,ADAM22,NAP1L1,P2RY13,ZC3H12B,IDNK,NFIA,NFYA,CNOT4,HCN1,NTRK2,NUCB2,ODF2,OPA1,OXTR,ZDHHC22,PBX1,PCSK1,ANLN,PIK3R1,RETREG1,HMGCLL1,PMP2,STRN3,ING3,SH3KBP1,TATDN3,PPP3CB,PPP5C,RANBP3L,PRKCZ,EPDR1,HYDIN,PTHLH,SPDL1,PTPRB,OCIAD1,FAM120C,PTX3,ACSM5,CCDC40,ARID4A,DBX2,KHDRBS2,RGS3,PRIMA1,MYH14,ROBO2,ELP2,PCMTD2,RPE65,EPHA10,BAALC,ATP8B4,ACER3,LRRK2,ATAT1,RTKN,ZNF354C,AP1AR,ATXN2,HOGA1,SCP2,TRIM46,GALNT10,ZFP30,CPEB3,DOCK10,ST3GAL3,SEC31A,SLC2A5,LRRC55,SLC6A8,SLC12A2,SLCO1A2,TET1,MBD5,SNRPN,PALLD,UNC80,TRERF1,SOX5,NMNAT2,KIF1B,CDK19,CAMTA2,MAPK8IP3,ZSCAN29,ELOVL4,NECAB1,FGD4,PRRC2C,PLCB1,SYT1,COBL,ANKRD28,C12orf76,TACC1,KAZN,EXOC7,FAM208A,UNC5D,ANO4,VWA3A,TCF7L2,TRIM2,CLASP1,SYNE1,DOCK9,CRTC1,RNF216P1,TK2,TMOD1,FAM124A,RBFOX2,ZNF346,ELP5,STXBP4,SSBP2,HEPACAM,EIF4ENIF1,DNAJC12,PITPNB,CLIP2,ZNF781,NSD2,PCDH20,ZNF28,ZNF45,ZBTB16,WNK1,RNF103,MDH1B,PCDH15,NAV2,TMEM163,PDSS2,PAK5,ZNF248,FXR1" MicroRNA hsa-miR-325:mirSVR_lowEffct hsa-miR-325:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.20E-99 2.92E-95 3.10E-98 2.85E-97 259 1097 "FAM43B,KLHL32,KIDINS220,SLC44A5,MTUS1,CARNS1,LCORL,ANXA7,CNTNAP1,APBA2,CACHD1,API5,ARHGDIA,PLA2G4C,ASPH,CCDC181,BCHE,CFLAR,BMPR1B,BTK,CASTOR3,SGCE,IL33,CALB1,PTBP2,CAMK2D,CANX,CBR1,CERS5,CD38,SEPT7,LRRFIP1,SRSF11,B4GALT6,JAM2,NDST3,CLCN3,COG1,FAM19A5,QKI,TMEM155,ARHGEF6,CNTN1,PCYT1B,AKAP6,COL4A5,ABI3BP,NRG2,CNRIP1,CHD1L,CREM,HAPLN1,CS,MICAL2,APPL1,PHF14,CTH,CFAP61,NRSN1,DOCK4,RIPOR2,FRMPD4,TOX,DAPK1,PITPNC1,ZEB2,BLOC1S6,FBXO25,SPOCK3,DMD,DYNC1I1,ARRDC4,ECM2,ABCC9,WDPCP,ATL1,FRY,FSD1L,KMT5B,EIF1,OLIG2,LRRC23,MRVI1,F3,FCGR1A,FDFT1,GORAB,FECH,SEC24B,FGF13,FGF14,SEMA4D,FLT1,C2orf88,NBEA,ERGIC3,DACH2,TVP23A,GABRG1,GABRG2,HBS1L,BRPF3,B4GALNT1,RAPGEF6,IQGAP2,LRRC37A6P,KIAA1841,GATM,GCNT2,SULT1C4,GPR162,GGTA1P,GK,GLS,PCDH11X,MAP7D2,GNAL,FERMT2,WDFY3-AS2,GPM6A,EML4,TMEM121B,TPPP,GRM3,COQ10A,TMEM25,AP4S1,HMGB1,AGBL5,HSP90AA1,LRRCC1,ITPKB,SLC35G1,OLFM3,MAN2A2,MAP4,MATN2,MBD1,LRP1B,MEIS1,SRSF12,AFF1,MPP2,CTNNA3,MYT1,FXYD6,P2RY13,NEUROD2,SMIM11A,NTRK2,ODF2,OGDH,P2RX7,GPR137C,PDGFRA,CCSER2,PCDH18,LRP12,TNPO2,SH3KBP1,PPM1B,PPP2R2B,CRLS1,RANBP3L,RASGEF1B,PRKACB,MAPK4,MAPK9,GON4L,ANKHD1,PTN,TMEM260,ZSCAN32,PTPRG,PEX2,CCDC40,ZNF793,RALGDS,ATG16L1,FAT4,OXR1,VEPH1,MSANTD2,RPRD1A,KLHDC8A,CARF,RORB,ACER3,ABCA11P,CLIP1,MIR124-2HG,SCN8A,LINC00461,MRAS,ARX,FBXO11,NLGN1,CTXN2,SLA,SLC12A2,SLCO1A2,GKAP1,SMARCE1,RCOR3,SNRPN,UNC80,DOP1A,WDTC1,MYT1L,SOX5,DOK5,SP2,KDM4C,ZC3H13,RBM26,SRPK2,TROVE2,ZC4H2,LARP4,SYP,C12orf76,DDHD2,UNC5D,ZFP90,TRIM2,DOCK9,PHF24,ARHGEF12,PUM2,FRYL,DICER1,SPX,AP4E1,HHIP,BHLHB9,RIMBP2,TPD52,AMACR,FAM155A,UGT8,PITPNB,FLRT2,TBC1D15,RICTOR,ZNF711,MICU3,ZNF28,ELFN1,ZNF195,PLPPR5,WNK1,EMSY,PCDH15,PLSCR4,FAM219B,NETO1,SOCS4,LAS1L,SENP7" MicroRNA hsa-miR-514b-5p:mirSVR_highEffct hsa-miR-514b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-99 3.08E-95 3.27E-98 3.01E-97 258 1089 "CPNE2,SDE2,NBAT1,SLITRK1,DPY19L2P4,GPR158,HECW2,ALCAM,SRPX,OGT,PPP4R4,TMEM263,CDK13,MARCH3,EIF4G3,N4BP2L1,LINC00847,BCL7A,DCAF5,CFLAR,DST,CALM1,KALRN,TRIM41,CANX,VXN,ZNF501,LRBA,SEPT7,CDC42,CDH18,CCPG1,GPR37L1,CHGA,KMT2C,TJP2,QKI,MAP4K4,NIPBL,TMEM155,ARMC8,BTF3L4,FAM171B,PREPL,RBM39,RNF14,MROH8,CSNK1G3,NCAN,SOCS5,NOS1AP,FGFR1OP2,RIPOR2,KIAA0586,DGKB,TMEM170A,GIT2,DCC,ZEB2,HP1BP3,SACS,FAM107B,DLG2,DYNC1I1,CPEB2,DPH1,RCAN1,FAM78B,EDN3,EDNRA,SGK2,FCF1,FRY,PHF20L1,SUGP2,ELAVL3,KCNMB2,STX2,SIRPB1,EXTL2,F3,F5,FAM198B,ZNF461,ACSL4,GORAB,POLR1B,FOXG1,SYNCRIP,NBEA,SMC2,CELF1,ST6GALNAC3,MSANTD4,NRG3,OGA,STAG2,MEGF11,CAB39,BRPF3,GATM,PCDH17,LYVE1,BRD8,GPR75,GLS,CBX1,INSM2,DCLK2,GPM6B,TMEM121B,RAPGEF4,DIDO1,SERP2,GRM5,GRM7,BTN2A1,PSIP1,RNFT2,FAM222A,TOX2,ARHGAP36,IDH3A,DOCK7,IL11RA,ITGAV,KCNK1,NCOA7,MBNL1,TM6SF1,MDM4,MMP16,ZNF680,ZNF92,MTTP,MYO9A,NEFM,NEFH,NF1,VWA2,CNOT4,NOVA1,PAK3,PDE3B,GNG2,OLA1,NALCN,CCSER2,SNX10,PRIMPOL,PMS2,SLC36A4,MINDY2,PPM1B,PPP2R5C,RASGEF1B,PKN2,MASP1,SYTL2,CNTLN,TMEM260,PTX3,PID1,OXR1,ZDHHC14,SLC6A15,ZYG11B,RET,ERI2,RFX3,RIT2,SEC61A2,PBRM1,ZFHX4,CARF,GSTCD,CCDC25,RPL15,UEVLD,ATAT1,KCNIP1,CLIP1,ATXN7,FNDC3A,SLITRK3,WDR37,PEX26,PPP4R3A,FAM214B,SLC6A8,CCDC88A,NAPB,SNCA,ZNF415,BDP1,KDM4C,RBM26,TAB2,ATP10B,PBLD,TROVE2,CLSTN2,NECAB1,VAMP1,DNAJC9,SYPL1,SYT1,PJA1,DDHD2,ADGRL3,AGTPBP1,KLHL4,TCF7,ZEB1,SYNE1,DOCK9,GPRIN3,PMS2CL,ITGB3BP,AP4E1,AKTIP,ARL10,TIAM1,HEY2,SEZ6L,TPM1,NPL,RGMB,PRMT8,RUNDC3B,AMACR,TSN,SGK3,RPL7L1,UBE2H,UBE3A,PLEKHH2,RICTOR,SLC13A3,ZNF711,ZNF708,MICU3,FSTL5,ZNF189,ANKS1B,PRDM10,HPS4,CIAPIN1,KCNAB1,MVB12B,RGS7BP,AMN1,DOCK8,PHTF2,TIGD6,FXR1,NETO2,NETO1" MicroRNA hsa-miR-507:mirSVR_highEffct hsa-miR-507:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.92E-99 3.32E-95 3.52E-98 3.24E-97 248 1008 "KCNH8,ABHD6,ACTN1,FAM43B,SLC25A25,ERMN,PWWP2A,ADRA1D,OLMALINC,HACE1,ALCAM,BCAR3,ABCD2,UNC79,AMPH,ZFAT,ANK2,PPFIA2,PPFIA1,ALS2,NCOA1,ATP2B2,B3GALT2,DOCK11,TTLL9,BACH1,RGS9,BCL7A,SYNJ1,JAZF1,CACNB2,CANX,PRC1,CCK,TMEM257,LRBA,ZMYM4,LOC730101,MAGI1,CHGB,RAB3C,B4GALT6,RAB28,KIAA1549L,CLCN4,NRXN1,CLTC,FAM189A2,IQCK,ARMC8,AKAP6,BTF3L4,SLC4A7,SLC4A8,TBPL1,MYRIP,SEC31B,ARHGEF10,PLXNA4,DZIP3,ERC2,PHF14,RIMS2,RIPOR2,LONRF1,KIAA0586,GIT2,ELMSAN1,ZEB2,KIAA0753,LYPD1,RHOBTB1,CPEB2,ABI1,DSCAM,DNAJB6,DYRK1A,ABCC9,EDIL3,WDPCP,EDNRA,ANKRD46,CNNM1,KLHL5,GPR61,PHF20L1,KMT5B,EIF4G2,EIF5,ELAVL4,RGS17,DCTN4,EMX2,EPHB1,SRRM1,DLC1,MED12L,KIAA1109,FHL1,FLT1,C2orf88,POMT1,ARFGAP2,KHDRBS3,NSG1,STAG2,GABRA2,C15orf41,GATM,TUBA8,AHDC1,PCDH17,DHRS4,GLS,PRUNE2,PCLO,GRIA2,GRIK2,NR3C1,GRM7,LINC01551,BACH2,HMGCL,HNMT,HNRNPK,MSL1,IDH3A,ZNF181,ZIC5,LRRTM3,SLC35G1,OLFM3,KCND2,KCNJ3,KCNJ9,TTYH2,LAMP2,FGFBP3,MAP4,MARK3,MATN2,MATN3,MEIS1,MIA2,MOG,COL28A1,SESN3,ADAM22,NELL2,NEUROD1,NKX2-2,NPTX2,NTRK2,NTRK3,OXTR,GLIPR1L2,PAX6,PCDH9,ABCB1,ING3,PRKCZ,MAPK9,SLC26A11,HYDIN,SAMD9,MDGA2,CNTLN,TMEM260,PTPN13,PTPRD,PTPRG,PTPRO,STRC,USP47,DBX2,REV3L,RFX3,RORB,PCMTD2,CCDC102B,FBXW7,ZC3H14,STK32B,LRRK2,ABCA11P,SEMA6D,ATXN7,SCN3A,LRRTM4,TNFRSF19,SELL,COPZ1,FERMT1,CHD9,PPP4R3A,DHX30,KANSL3,RAB3GAP1,EFHD1,ATF7IP,TET1,DMRTC1,SMARCE1,RCOR3,LMBRD1,UNC80,SP4,SRPK2,NXT2,SEPT8,SYT11,ZC3H4,ARHGEF9,ADAMTS17,ANKRD12,AGTPBP1,ANO4,DMXL2,ZFP90,SYNE1,PCDHB7,FRYL,ITGB3BP,RBFOX2,RGMB,RFTN2,PRR18,ZNF610,FAM155A,UBE3A,AMOT,PLEKHH2,MEAF6,VIPR2,XRCC4,CFAP298,ZIC1,ZNF708,ZNF540,FMN2,SIGLEC10,PDSS2,AMN1,UBE3B,FBXO36,RNF170,SLC4A10,SENP7" MicroRNA hsa-miR-34b*:mirSVR_highEffct hsa-miR-34b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.05E-99 3.40E-95 3.60E-98 3.31E-97 256 1073 "NDRG3,ADCY6,ADD2,ADORA2A,ZNF608,GPR158,KCTD16,KIAA1324,ZNF578,TAOK1,LRRC7,ALCAM,FAM135A,AMT,ANK2,ANK3,API5,TMEFF1,LINC00173,ASCL1,CAPRIN2,ZBTB10,ATM,ATP1B3,B3GALT2,DOCK11,ADAM23,BACH1,CFLAR,SYNJ1,JAZF1,WASF1,CACNA1A,CALB1,THSD7A,PTBP2,SPAG9,CD86,DGKI,DCLK1,LGI1,MAGI1,DLGAP1,RAB3C,B4GALT6,LHX2,CLTC,FAM19A5,SULT4A1,HECTD1,TMEM155,SLC4A7,PREPL,CREM,ENTPD4,NCOR1,SIPA1L1,SOCS5,APPL1,PNPLA8,CTNND2,PUM1,PPP6R2,ST18,USP6NL,TOX,TBC1D5,TMEM170A,GIT2,ELMSAN1,KLHL3,RABGAP1L,ARNT2,USP3,DPP6,ECM2,DNM1L,E2F5,EDIL3,SNX29,SEMA3D,FSD1L,CELSR3,APH1A,TENM1,ELAVL2,PLEKHA1,CALCRL,VPS13B,LRRC17,GPHN,NRN1,FAM198B,ZIC4,FDFT1,POLK,RGPD5,C2orf88,WDR83,FAM49B,STAU2,MSANTD4,GABRA1,GABRA2,ZMYND11,ARPP21,IQGAP2,TUBGCP4,MSTN,GNAS,GOLGB1,GPD2,GPM6B,FUT10,GPR22,GRK4,GRM1,TMEM25,WIF1,ELOVL5,AGFG1,SHISA6,IGFBP1,ZIC5,INSM1,ITPKB,KCNA1,KCND2,KCNMA1,KTN1,LAMP2,PAXBP1,SYTL4,LSS,CLEC18A,MAN2A2,MAT2A,MATN2,MBP,MDM4,MEST,MITF,SCG3,CTNNA3,MYCN,MYO9A,NEK1,NEUROD1,CNOT4,OPHN1,CNTN3,PDGFRA,CDK14,ABCB1,PIK3C2A,XRN1,JAKMIP1,PLIN1,EXOSC10,ING3,SEPT4,MAPK4,DCHS2,MASP1,APTX,SIDT1,GON4L,PTHLH,ELOVL2,PTPRG,QDPR,USP47,RDX,FIGN,RGS4,SLC25A36,RIC8B,TMLHE,SPIN3,ATP8B4,ATAT1,RYR3,SCN3A,SCP2,ELMOD1,SLC30A10,HSPA4L,ITSN1,SHC4,ST3GAL3,CTXN2,ANKRD6,PPP4R3A,DMRTC1,CDK5RAP2,RIMS1,SNRPN,PALLD,MYO16,FAM219A,SON,TNIK,HECW1,MYCBP2,SPP1,ZC3H13,KIF1B,CDK19,NPAS3,RAP1GAP2,ITPRID2,ZC4H2,ERBIN,ZSCAN29,SULF2,ZC3H4,VPS13A,SYT1,MTCL1,FAM208A,ATMIN,TPCN2,TRIM2,SYNE1,GPRIN3,DICER1,TLR4,LRRC8A,RIMBP2,TPM2,DCBLD1,KCNE5,TSN,TTC3,UBTF,WIPF1,NSD2,CLDND1,RICTOR,ZNF540,ZNF74,FSTL5,ZNF184,ANKS1B,CADM2,DNALI1,LMAN2L,ADAMTS9,NAV3,FAM47E,PHTF2,FBXO36,JMJD1C,NHSL1,NETO2,NETO1" MicroRNA hsa-miR-2114*:mirSVR_lowEffct hsa-miR-2114*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.87E-99 4.42E-95 4.67E-98 4.30E-97 284 1312 "ABAT,KCNH8,KDM5D,FAM43B,NDRG3,PSMG3-AS1,CCDC85A,PNMA8B,FZD9,KIAA1211,AP2A2,TXNDC16,CC2D2A,ALAD,ABCD2,MAP4K3,CNIH2,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APOC2,MIER1,IGDCC4,LINC00173,ALDH4A1,ATM,ATP2B2,ATP2B3,MTMR9,B3GALT2,KIF1A,TTLL9,BBS2,SYNJ2,MTMR3,IL33,MMD2,CA4,KALRN,HAP1,PTBP2,TRIM41,RUNX1T1,SCARB1,ENTPD2,CDC42,LGI1,LHX2,EPS15L1,PPT2,NGEF,LY86,IGLON5,SLC4A8,ABI3BP,MFSD4A,SH2B1,ANKRD44,SEC24C,LRIG1,SUSD5,FAM169A,MYADM,EARS2,ZNF337,DAPK1,GIT2,KIAA0753,RHOBTB1,SV2A,KBTBD11,CHRDL1,DLG3,DNM1,HS3ST4,USP3,CD99L2,MED12,DNM2,DMTF1,DPYSL2,DRD1,ABCC9,GOLT1B,PHC2,FCF1,TMTC1,YAF2,KMT5B,ELAVL2,EMX2,EPHB1,ANKRD13B,RRAGB,SIRPB1,GMPR2,WAC,ZIC4,CHST15,GTF2IRD2,OLFM1,CAMSAP1,HPCAL4,NELFCD,USP21,CGREF1,SARAF,TPPP3,FYB1,SDCBP2,DKK3,AHCYL1,FAM120B,ARPP21,GAP43,SIGLEC8,MYOZ2,GCK,GGTA1P,ZNF276,TCERG1,RNPS1,TOX3,ZNF638,KCNMB4,DCLK2,GNAS,CCDC184,GPR17,STON1,STMN2,GRIN2C,GRM2,GRM7,CLASRP,GSTM5,SOX21,FAM107A,SLC2A6,ATOH8,FRMD5,VSIG4,SYNPO,SHISA6,SCIN,INPP5B,KCNK3,KHK,KIFC3,HECTD2,NCOA7,ZNF667-AS1,ADAM22,MSR1,NCAM1,CCDC13,NEUROD2,NODAL,DNHD1,NPPA,SMIM11A,TBC1D25,KCNK10,PALM,PCDH9,PDE4D,PIRT,GNG2,XRN1,KCTD15,HMGCLL1,PRRX1,MBOAT7,POLG,PPARA,PPP2R5C,PRKCG,PRKCZ,MAPK7,CNTLN,BDNF-AS,TMEM260,C1orf109,RAD52,NWD1,RASGRF1,FEZF2,SLC6A15,CRTAC1,ZMAT4,ERI2,RGS4,RGS12,ARHGEF10L,ROBO1,MRAP2,SNX22,NEK11,ATP8B4,GLDN,STK32B,MAP6D1,HSD11B1L,ZNF331,DGLUCY,SEMA6D,SCN2A,SMPD3,SOX6,SCG5,WDR37,NAPB,BTBD7,SLC20A2,SLC22A4,SLIT1,ARFGAP1,SMARCC2,CDK5RAP2,INTS9,WDTC1,SP2,ZSWIM8,CLUAP1,UHRF1BP1L,PEG10,KIF1B,IQSEC2,NFASC,MESP1,NKAIN2,STAU1,TTBK2,PHLDB1,FGD4,RHBDL3,DNAJC9,PLCB1,SYN2,MLST8,PDLIM2,CNTN2,EHBP1,TCF4,ZEB1,TPCN2,TRIM2,WDR7,FRYL,HIF3A,PMS2CL,ZFPM2,AP4E1,CDH22,SLC44A1,ZFP91,TNFRSF1B,CSMD1,PIK3R5,TPM2,FNDC5,RUSC1,TMPRSS5,LRTM2,SLC35A4,PITPNB,NSD2,SPHK2,TMEM198,PLPPR5,ZNF213,DHX33,INTS3,GAL3ST3,URM1,WIPF2,MVB12B,PDSS2,FAM13C,DOCK8,ST7,UBE3B,FXR1,AP3B2,SOCS4" MicroRNA hsa-miR-146b-3p:mirSVR_lowEffct hsa-miR-146b-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.34E-99 4.69E-95 4.95E-98 4.56E-97 299 1446 "ACHE,CSMD2,GALNT13,ADD2,SLC12A5,KIAA1211,NLGN4X,SNX32,TXNDC16,ZNF687,ANK3,FAM131A,CDK10,SPTBN4,PLA2G4C,CAPRIN2,NCOA1,ASTN1,CHID1,MTMR9,ADAM15,BACH1,BARD1,RGS9,NRP2,SYNJ1,SYNJ2,CASTOR3,GYG2,SGCE,PTBP2,SPAG9,LDB2,USP2,MTMR7,P2RX6,AP4M1,LRRFIP1,GPR37L1,CHN2,MS4A7,TAOK2,EPS15L1,NMT2,TMEM155,ARHGEF6,AKAP7,ANKRD35,COL9A2,MFSD4A,CHD1L,PNKD,CRMP1,NCOR2,ARHGEF10,CSNK1E,CSNK1G3,PLCH2,RIMS4,CNTNAP2,PLXNA4,SDC3,UBXN2A,PPP6R2,FAM131B,CCDC144A,GAPVD1,DCAF8,EARS2,CTIF,DBN1,ELMSAN1,DGCR5,ZEB2,HP1BP3,LYPD1,GUCD1,POM121,RHOBTB1,PARD6A,GRIN3A,DNM2,DOCK2,TOM1,MAMLD1,ABCC5,FAM135B,SEMA3D,GPR61,EGFR,PLEKHA1,ELN,VPS13B,COQ7,DMTN,DENND4A,ADGRV1,F3,F5,FABP7,ATP8A1,RACK1,TOMM40L,PPP1R1B,FGF14,ANKFY1,TRIM16,ZNF605,ERGIC3,DACH2,ABLIM2,ZNF559,TUBGCP4,GFER,PCDH11X,KCNMB4,WDFY3-AS2,PSRC1,GPD1,GPD2,PRUNE2,NUDT21,DIDO1,GRIA4,GRIK1,SPACA9,GRM1,GRM5,GRM7,GRM8,KIF3A,CLASRP,GSTM5,BVES,LINGO1,MAEL,NXPH3,ATXN2L,TNFAIP8L3,MIER3,ELOVL5,HMGCR,IGFBPL1,ZNF491,ZDHHC15,CPT1C,OPALIN,DHX35,HSP90AA1,CELF5,LRRTM3,ITGA7,SLC35G1,KCNA1,KCNA4,GPR62,KCNJ3,KCNJ10,KCNK3,KCNN2,STXBP5,TTYH2,ZFYVE27,MAP4,MBP,MEIS1,SRSF12,XRRA1,MOG,ADAM22,MSR1,MDGA1,MYO6,SFR1,RCOR2,NEK1,VWA2,HCN1,NUMA1,SNTG1,PDGFRA,PFKFB2,PFKFB4,GDAP1L1,ZNF655,PKD1,MTRF1L,PLXNB1,PNMA3,SCHIP1,PRRX1,RETREG2,NXPH1,TMEM235,MED1,CRLS1,PPP3CB,GRAMD1C,CNNM2,SLC22A23,WBP1L,DEF8,PTH1R,PTPRD,RAB3IL1,RAB5B,FAM66C,ZNF493,SLC6A15,RGS12,MRPS18A,SEC61A2,TMLHE,EPHA10,RPL15,LRRK2,MEG3,HSD11B1L,FAM192A,DGLUCY,HOGA1,LRRTM4,ELMOD1,IL17RB,GALNT10,SUPT20H,ITSN1,MAGI3,FHOD3,BCAN,SLC6A7,SLC6A11,YPEL4,RADIL,NAPB,TMEM132D,CXXC4,ABTB1,OGDHL,ANKRD36,KIF13A,FAM126B,UNC80,RBM34,SCN3B,ZCCHC24,SOX10,KDM4C,NPAS3,NFASC,C11orf87,ERBIN,ST5,RGL1,DIP2A,GANAB,FGD4,PRRC2C,VPS13A,MLST8,SMG6,MGRN1,ATMIN,SATB2,WASHC4,AKNA,TNS2,CRB1,LEFTY2,THRA,TPM3,TPM4,WBP2,ELP5,TRIO,SSBP2,FRRS1L,LAT2,ZNF708,ZNF19,FMN2,CELF4,AMZ1,EML6,MEIS3,EMSY,PRDM2,DNALI1,LINC02210,TUBA1A,NAV3,PPP1R3F,FIP1L1,TRIM16L,PARP11,UBE3B,RSPRY1,MSRB3,SOCS4" MicroRNA hsa-miR-4293:mirSVR_lowEffct hsa-miR-4293:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.16E-99 5.15E-95 5.43E-98 5.00E-97 274 1226 "RALGAPA1,TTYH1,SYS1,ACTN2,GPRIN1,KLHL32,GALNT16,ADD1,RNF150,NLGN4X,SLC24A4,KCTD16,KIAA1324,SRPX,FGD2,USP28,PHF12,LGR5,AQP4,AQP6,SFMBT2,CASK,ARRB1,CDK13,ATP2B1,SLC2A11,BACH1,BCS1L,DCAF5,ARHGEF7,SCAPER,CACNG1,PTBP2,VXN,CAST,CBR1,CD38,ARHGEF2,LGI1,DLGAP1,SRSF11,PLEKHB1,CLU,NIPBL,PCYT1B,ARMC8,ANKRD35,BTF3L4,TCEAL2,ZNF521,ANKRD44,SNCAIP,ARHGEF10,VAC14-AS1,PHACTR3,FAM169A,APPL1,CMTM5,GREB1,CTNND1,CYBB,LIN54,AIF1L,SIRPA,DBN1,PITPNC1,YTHDC1,PLEKHM1,MYEF2,CNIH3,FBXL5,RHOBTB1,RABGAP1L,KIF19,ZNF582-AS1,DLG2,DSCAM,DYRK1A,E2F6,MRO,BSCL2,EPB41L1,EPB41L2,SEZ6,CEP85L,ADGRV1,TBC1D16,FER,ATP13A4,FLT1,ARFGAP2,NSG2,STAU2,HRASLS5,GABRG1,BRPF3,NEK6,SEPT9,SRRM4,LRRC37A6P,USP19,ZNF638,LUZP2,ZNF782,LILRB4,TDRKH,FUT10,GPR17,CECR2,C1QL4,GRIK2,SPACA9,ADAMTS13,ADAMTS8,GRIN2C,GSTM5,GUCY1A2,FAM222A,WIF1,MAN1B1,MYLK2,INSM1,ITGA7,ITGAV,KCNA1,KCNA6,KCND1,KLC1,LMO2,MAOB,MAP2,IL17D,TM6SF1,MEIS1,AFF1,MMP16,MRPL42,SESN3,ADAM22,CTNNA3,RTL5,MYT1,NAP1L1,NAP1L2,NDP,NODAL,NPTX1,NTRK2,NUCB2,OPHN1,LOC100128398,PCSK5,PDE1B,GNG2,SEMA5B,CCSER2,SNX10,ZFYVE21,FTO,HMGCLL1,PURG,C11orf49,EXOSC10,ING3,POLG,SH3KBP1,POU6F1,PTPA,PRKAB2,MAPK4,GRAMD1C,MASP1,BCAS3,PIGG,MTMR10,PXK,PTPRD,FAM120C,RALGDS,SUSD4,NWD1,DBX2,RBBP6,BSDC1,UBR7,KLHL11,CCDC82,KLHDC8A,ARMC5,CARF,RORB,RPL15,ATAT1,RXRG,ZNF331,LRRTM4,TRIM46,SFPQ,ASRGL1,RASA3,SGK1,FAM102A,MAGI3,CNKSR2,SEC31A,ZNF365,PEX26,EPN2,FAM214B,SLC6A9,SEPHS1,SLC12A2,ZNF667,RIMS1,SNAP25,MBD5,SNRPN,TMCC1,KDM4B,FAM219A,SON,KDM3A,ENKUR,IDI2-AS1,TSPYL2,NPAS3,SSTR1,SSTR2,ZC4H2,SSPO,INKA2,TTBK2,SULF2,ZC3H4,PRRC2C,ARHGEF9,VPS13A,SYN2,TAL1,CNTN2,TPCN2,TRIM2,TMEM151B,PCDHA5,AHCYL2,LEFTY2,GPR161,ZNF106,SLC44A1,NR2E1,TPM3,ZNF384,SMUG1,AMACR,TRO,ANO5,FLRT1,MEAF6,GUSBP1,ZNF24,TRIM9,GPR158-AS1,MKRN3,CELF4,FSTL5,MAP3K12,HPS4,PDSS2,HNRNPA3,CASC15,KLHDC1,CBLN2,AP3B2,FAM198A" MicroRNA hsa-miR-1185:mirSVR_lowEffct hsa-miR-1185:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.49E-99 5.33E-95 5.62E-98 5.17E-97 263 1133 "KCNH8,ACADM,NCKAP5,SLITRK1,CDC7,WDR35,OSBPL8,SPOP,SRPX,MARCH4,GOLGA7B,ANK2,C6orf89,PPFIA1,EPB41L5,BCAS1,USP37,PLA2G4C,SNAI3-AS1,SEC11C,BMPR1B,IL33,DDR1,CACNB4,CALM1,KALRN,VXN,CAST,PRC1,CBLN1,USP6,MTMR7,LRBA,SEPT7,CDH10,DCLK1,LOC730101,DLGAP2,CFL2,SRSF11,CHM,PLEKHB1,CASC2,KMT2C,KIAA1549L,CLTC,FBXO7,SRP14-AS1,HECTD1,NIPBL,CNGA3,AKAP7,RCHY1,BAG4,CPS1,ENTPD4,CRY2,SLC32A1,GDA,CRYM,RGS6,SEC24C,SUSD5,PHACTR3,SDC3,CTH,NRSN1,EDRF1,HDAC9,IST1,MFAP3L,HP1BP3,SV2A,SGSM2,DLG2,DPH1,MAMLD1,DYRK1A,FIS1,E2F6,EDIL3,FCF1,FRY,ELAVL4,EPB41L2,SEZ6,KCNMB2,ZNF549,RCSD1,ZNF589,SLC9B2,FGR,POLK,SUCO,SCARA3,SEC23B,SYNCRIP,STAMBP,TPK1,ATP2C1,DLL3,STAU2,NRG3,MEGF11,AHCYL1,ARPP21,TMEM8B,LRRC37A6P,GBX2,AHDC1,LYVE1,BRD8,SPIN1,PCDH11X,GPD1,GRIA2,GRIK1,ADAMTS13,GRM5,GRM7,RNF165,ARHGAP19,NCKAP1L,HMGB1,ZNF491,NEGR1,SHISA6,ZNF678,KCNH2,KCNMA1,KLRC2,LMO2,SYTL4,HECTD2,ARHGAP12,ASPRV1,MAP4,MARK1,LYPLAL1,SYT9,MEIS2,MMP16,MRPL42,MSR1,NRBP2,DDX25,LAYN,ZC3H12B,NELL1,NEK1,CNOT4,NOVA1,DNHD1,LOC100128398,CLDN11,PCDH9,GNG2,BEST3,A2ML1,SNX10,RETREG1,PDZRN4,RETREG2,NXPH1,PPP2R5E,PPP3CA,RASGEF1B,PRKACB,LRRC49,LAMA1,CNTLN,UHRF1BP1,NCR3LG1,SPDL1,PPP2R3C,RAB5B,TMEM255A,ZNF793,SH3TC2,RASGRF2,GTDC1,CARF,GSTCD,UEVLD,SPIN3,PRR5L,RPS6KA2,SYNDIG1,KCNIP2,FOXRED2,SEMA6D,ATXN7,SCN3A,SCN4B,LRRTM4,FNIP1,COPZ1,KIF21A,PPP1R9A,FERMT1,NTNG1,ST6GAL1,CCDC92,EFHD1,BTBD7,ATF7IP,MYH15,TMCC1,FAM126B,SCN3B,SON,SP2,GLT8D1,SPART,LHPP,SSTR1,NKAIN2,NXT2,ST5,STAU1,NEK4,KANK1,AJAP1,SUPT5H,VPS13A,ANKRD28,DDHD2,CNTN2,SIN3B,CUX2,TPCN2,ARHGEF12,USP32P1,RNF216P1,AP4E1,HHIP,AKTIP,SLC44A1,ERCC6L2,KCTD2,RBFOX2,NPL,NR2C2,STXBP4,RUSC1,ANO5,HIRA,SLC13A3,XPO1,ZNF74,MKRN3,ZBTB38,LRP8,ADAMTS9,PCDH15,NAV3,SLC17A6,PDSS2,PAK5,KAT6A,IFT88,NETO1,SLC4A10" MicroRNA hsa-miR-8485:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-98 5.74E-95 6.04E-98 5.56E-97 231 877 "CSMD2,TMEM132B,ADCYAP1R1,PNMA8B,ESYT2,PTCHD1,MTA3,TAOK1,GOLGA7B,PDZD4,AMPD3,LRFN1,ANK3,TNRC6C,CADPS,ATP1A3,ATP2A2,CADM3,DPY19L3,BACH1,JAZF1,BSN,FOXK1,CA8,CACNA1B,KALRN,CANX,LONRF2,CDH2,TBRG4,CRLF1,CFL2,RAB3C,B4GALT6,STOML1,TMEM184B,COL9A1,TBPL1,TOGARAM2,NRG2,CREB5,CRY2,ANKRD44,PLXNA4,NOS1AP,KIAA0408,HDAC9,MYADM,RASSF2,LONRF1,RIMS3,DGKG,SPOCK2,DNAL1,DBT,MED24,KLHL3,SV2B,MTX3,FAM107B,CHRDL1,DTNA,EGR3,PLXNC1,SORBS3,EIF5,TMEM35A,C8orf37,TUBD1,ACSL4,CHST15,FGFR3,FOXF2,SYNCRIP,FLT1,SGIP1,AFF2,ZBED3,MPP6,HRASLS5,MTHFD2,SYT17,SEPT9,SRRM4,GCK,SRCAP,MMADHC,PPARGC1A,GLYR1,EML4,RAPGEF1,PARD3B,GRID1,GRIK3,CACFD1,NR3C1,GSN,GSTM5,IL1RAPL1,PADI2,FRMD3,BACH2,HLF,HMGCR,MSL1,C2orf72,SCIN,IL6ST,IBA57,ITPKB,JAK2,KCNA4,KCNB1,KCNJ3,KCNJ10,KLHL23,KCNK1,KIF5C,IPO5,LAMP2,SYTL4,FGFBP3,ARHGAP12,AFF1,MOBP,MPP2,JAKMIP3,MDGA1,HS6ST3,NEXMIF,PABPC1L2A,FXYD6,NDUFA5,NOS1,NPTX1,P2RY1,ZDHHC22,KCNK10,PDE3A,PDGFRA,GPR173,TMOD2,PIK3R1,PKD1,PLCL1,PLIN1,FAT3,PPM1B,CRLS1,DIRAS2,SNRK,PTCH1,SH3TC2,IQSEC3,RDX,ZMAT4,GTDC1,C12orf49,PNMA8A,KIRREL1,HUNK,ATAT1,STX1B,SEMA6D,SBF1,CSRNP3,ATXN1,SCN8A,TRA2B,CPEB3,WDR37,RAB3GAP1,SLC12A2,ATF7IP,SLC22A4,ZFP1,KIF13A,FAM126B,MYO16,PDZD2,WDTC1,TRERF1,FNBP1,LHFPL4,UNC5B,ZNF621,SS18,INKA2,SEPT3,AJAP1,NECAB1,RHBDL3,SYT1,ASTN2,SYT5,TMEM178B,TAL1,TCF7L2,TCF12,CLASP1,NAT16,GPRIN3,SIK3,HHIP,SLC44A1,GALNT17,NACC2,BHLHB9,DAAM2,BEX4,DOK6,NR2C2,PRMT8,ZNF610,UBE2H,UBTF,UGT8,WNT7A,SF1,NDRG4,CRB2,SLC30A3,SLC30A4,ZXDA,LRP8,ADAMTS9,HPS4,WNK3,MVB12B,FAM198A,SPATA13" MicroRNA hsa-miR-4316:mirSVR_lowEffct hsa-miR-4316:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.42E-98 8.00E-95 8.41E-98 7.75E-97 291 1377 "ASIC1,GALNT16,ADCY2,ADCY6,ADD1,ADD2,ADD3,BRAP,ADORA2A,KIAA1211,ESYT2,ADRB2,KIDINS220,HACE1,CC2D2A,AK2,PLA2G6,LRRC7,KIF6,FGD2,MAP4K3,PPFIA4,CNTNAP1,CPNE5,CDK10,PPP4R4,CDK13,DNAH17,CAPRIN2,ATP1A2,RNF182,MTMR9,BCHE,CFLAR,CDK5R1,DST,ARHGEF7,GPC2,BAIAP3,CFAP410,CANX,NFS1,SHISA7,CLDN10,CCKBR,ARHGEF1,CBFA2T2,CDC42,CDH10,LARGE1,CFL2,CHM,SYNPR,PLAA,CLTC,ABCG2,ARMC8,CABP1,ANKRD35,ACBD5,CNRIP1,MFSD4A,CHD1L,CSF1,CSF1R,VCAN,PDE4DIP,RASGEF1C,DZIP3,FAM131B,CYBB,ARHGAP24,LONRF1,PHYHIP,TMEM170A,DAPK1,DAPK3,DGCR5,ZEB2,MED24,SPOCK3,SRGAP3,SGSM2,SEC16A,ZNF582-AS1,EXOG,RAB39B,DNM1,DPH1,ACOT8,DRP2,TOM1,DUSP9,MAMLD1,EBF1,EDN1,OPTN,ABI2,STARD3NL,EIF1,EPB41L2,EPHB1,CDHR1,ABCA8,TUBB3,TUBB4A,CORO2B,TOMM40L,FCGRT,TESK2,FGF12,AMOTL2,SCARA3,CAP2,SEMA4D,PSD2,PRELID3A,CGREF1,B3GAT1,ADGRA1,AP4B1,NRG3,GABBR1,GABRB3,FAM120B,GART,LRRC37A6P,GCK,SULT1C4,MMADHC,RND1,GNAS,ZNF782,WDFY3-AS2,RAPGEF4,ADAMTS13,GRM2,FAM107A,ARHGAP19,ATXN2L,TNFAIP8L3,ARHGAP36,TLX1,LRRC75A,SHISA6,HTR2A,KIAA1755,SCRT2,SLC35G1,KCNA6,TTYH2,LIMS1,MAN2A2,LYPLAL1,AQP11,MBP,MEIS2,CD200,CPNE9,LYRM9,RTL5,NEFM,CNOT4,NUCB2,NUMA1,OPA1,OPCML,LOC100128398,CLDN11,CDK18,PDE3B,SLC10A4,SSH1,ANLN,XRN1,PKM,PLXNB3,FA2H,SH3KBP1,POU6F1,PPP1R1A,RAB39A,PRKCG,MAPK4,MASP1,SYTL2,CNTLN,UHRF1BP1,NCR3LG1,ZIK1,PTPRB,PTPRO,CEP97,RAD51D,RALGDS,NWD1,RASGRF1,KHDRBS2,DPF2,MORC4,RGS7,PRIMA1,KCTD17,ARHGEF10L,ATP8B4,ACER3,TCP11L1,HSD11B1L,ATAT1,RTKN,CLIP1,SATB1,SCN4B,LRRTM4,ELMOD1,PEAR1,SEC14L1,STUM,WDR37,SLA,SLC4A3,RPH3A,SLC9A5,KBTBD4,TMEM132D,ATF7IP,SPHKAP,SMARCD3,SMARCE1,SNCA,UNC80,WDTC1,BDP1,ZSWIM8,MYCBP2,KIF1B,IQSEC2,RAP1GAP2,C11orf87,TROVE2,ERBIN,SEPT8,DIP2A,SEPT3,NSFL1C,SLC37A2,SYT4,TACC1,CAMTA1,TAL1,CAMSAP2,PDLIM2,ADGRL3,KLHL4,USP22,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZMAT3,SLC44A1,HEY1,TK2,ERCC6L2,TMPO,TNFRSF1B,KAT6B,TNS1,PIK3R5,C9orf85,RGMB,SMUG1,TSC1,BEST1,ATP6V0E2,REEP1,TMEM237,MEIS3,STOX2,FIP1L1,LINC00632,SLC17A6,UBE3B,NUP214,SSPN,KLHDC1,PIANP,ST8SIA2" MicroRNA hsa-miR-890:mirSVR_highEffct hsa-miR-890:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-98 1.53E-94 1.61E-97 1.48E-96 257 1088 "RALGAPA1,ABAT,CLK4,CSMD2,FMNL2,ADD2,SORCS1,RNF150,PTCHD1,ADGRF5,AMPD3,PHF12,PPFIA2,APBA2,BCAS1,API5,SHTN1,MIER1,ASPH,NCOA1,ATP6V1G2,RGS11,SYNJ2,SCAPER,MTMR2,IL33,THSD7A,CALM1,KALRN,PTBP2,CAMK2D,RUNX1T1,KRIT1,USP2,C1orf52,DGKI,LGI1,B4GALT6,NDST3,LHX2,RAB28,NRXN3,NRXN1,CLTA,C4orf33,CNGA3,AKAP7,ARMC8,COL4A5,BTF3L4,AHCTF1,ACBD5,ZFP28,CNRIP1,HS3ST5,HAPLN1,ARHGEF10,CSNK1G3,ATRNL1,ST18,RUBCN,GAPVD1,FRMPD4,MATR3,PABPC5,GIT2,PITPNC1,ZEB2,HEPH,MYEF2,ELMO1,FBXL5,RHOBTB1,SV2B,EXOG,GRIN3A,HS3ST2,USP3,DYNC1I1,CPEB2,ECM2,ABCC9,AASDH,EDNRA,FRY,CELSR3,COPS4,PLEKHA1,C8orf37,EPB41L2,TLR7,F3,CLVS1,ZIC4,PPP1R1B,FER,FGF11,MAD2L2,POLK,CAP2,ATP13A4,MSANTD4,OGA,GABRG2,GAD2,AHCYL1,ZMYND11,GALC,GAP43,MTHFD2,MSTN,AHDC1,GLI2,GLS,LUZP2,GNG4,NUDT21,EML4,PCLO,RAPGEF4,GRB10,GRIA2,GRIA4,GRM5,ZNF496,BVES,UBE2QL1,ARHGAP36,MIER3,HMGB1,LRRC75A,SMAP1,IDH3A,ZNF181,IL6ST,DIPK1A,KCNC1,KIF5A,KIF5C,KIT,FGFBP3,ZFYVE27,MAOB,MATN3,MBD1,MBNL1,MDM4,MITF,MN1,MOBP,MOG,ZNF92,CTNNA3,MYCN,MYT1,NF1,NODAL,NRCAM,NRGN,NUCB2,GLIPR1L2,PCDH8,PCSK2,PDE1B,PURG,PRRX1,SDK2,SPATA6,MINDY2,PPP2R5C,PPP3CB,GRAMD1C,PROX1,GON4L,TMEM260,ZSCAN32,PTPRB,FAM120C,ZNF615,RAB5B,CCDC40,FAM66C,GTDC1,RGS12,ZFHX4,SETD5,TMLHE,NEK11,MCMBP,ADAL,LRRK2,SATB1,ATXN2,SCN2A,SCP2,TRA2B,CHD9,DZIP1,RUFY2,CCDC88A,TET1,CDK5RAP2,SMARCE1,ANKRD36,LIMCH1,RIMS1,SNAP25,CABCOCO1,SNRPN,PALLD,UNC80,USP33,DOK5,KDM4C,DBNDD2,KIF1B,MCF2L2,RBM26,SPART,MPRIP,STAU1,RGL1,FGD4,ARHGEF9,SYPL1,SYT1,PJA1,DDHD2,FAM208A,ZFP90,TCF7L2,PCDHB9,PCDHB4,OBSL1,USP32P1,SIRT1,C18orf54,TJP1,TLR4,TRPC3,TRPS1,PPIL6,ANO5,TMEFF2,OSBP2,GPR158-AS1,LYPD6,FSTL5,EMSY,CADM2,PRDM2,ADAMTS9,MVB12B,C12orf4,JMJD1C,ZNF248,FRMD6" MicroRNA hsa-miR-646:mirSVR_highEffct hsa-miR-646:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-98 1.62E-94 1.69E-97 1.56E-96 226 843 "RALGAPA1,ACADM,TKTL1,CDC7,SLC44A5,KLHL13,TAOK1,FAM135A,ALK,PPFIA1,NT5C3B,CACHD1,TNRC6C,AQP6,STK33,CCDC181,BACH1,CFLAR,NAE1,JAZF1,IL33,CA4,LURAP1,CANX,SYT6,LDB2,AIFM1,LRBA,CDC27,SYNPR,NDST3,KMT2C,NRXN3,IGFBP7-AS1,HECTD1,LY86,CNTN1,AKAP6,BTF3L4,ABI3BP,AHCTF1,BAG4,ACBD5,ZFP28,HS3ST5,AKAP12,ARHGEF10,ATRNL1,DZIP3,CTH,CTNND1,USP6NL,DOCK4,GAPVD1,ARHGAP24,DCAF8,IST1,SCRN1,DCC,MYEF2,KIAA0753,ZC3H11A,AK5,DLG3,ARRDC4,DYRK1A,DNM1L,ABCC9,SGK2,FRY,TENM1,VPS13B,RCAN2,NRN1,ARMCX1,ACSL4,TAOK3,DLC1,FKTN,GORAB,SLC9B2,SCARA3,IP6K2,NBEA,SMC2,NPTN,DACH2,TPPP3,GABBR1,GABRA1,GABRG2,AHCYL1,ZMYND11,SALL3,DNER,PPARGC1A,KIRREL3,BRD8,RAB30,ZNF638,MAP7D2,GNAS,CCDC184,LPAR4,STMN2,DIDO1,GRM7,BVES,GYG1,FRMD3,ACOT7,SMAP1,IRF8,IDH3A,C2orf72,NKD1,ZIC5,RBPJ,TJAP1,DIPK1A,KIF2A,KIF5A,KLC1,LAMP2,INSYN2,SYTL4,NCOA7,C2orf80,ASPRV1,PACRG,LYPLAL1,MDM4,MOV10,CCDC80,NEUROD1,SLC11A2,OCRL,GPR88,OLR1,PCMT1,ANLN,PIK3R1,PURG,PMP2,NXPH1,SH3KBP1,PPP2R5C,PPP3CB,PKN2,HYDIN,GDPD2,MTMR10,RBBP6,ERI2,SEC61A2,SLC25A36,ZFHX4,ROBO2,YY1AP1,RPE,TMEM100,ATAT1,HOGA1,SCN2A,KIF21A,ITSN1,KIF16B,CHD9,FNDC3A,EFHD1,TET1,ZFP1,SNCB,MBD5,SNRPN,TMCC1,MYT1L,TRERF1,SOX5,ZSWIM8,ZBTB43,NPAS3,POGZ,KANK1,GANAB,FAM168A,ACSBG1,MTCL1,CAMTA1,CAMSAP2,SATB2,TCF7,ZEB1,TPCN2,WASHC4,WDR7,TEX15,SIK3,CRB1,SPX,ITGB3BP,MTMR14,NR2E1,ERCC6L2,TPM3,ELP5,NEIL2,AMACR,DCBLD1,TSC1,HSPBP1,TTPA,CADM1,RPRM,PLEKHH2,BEST1,TBC1D15,XRCC4,PCDH20,ZNF74,LAMP5,PRDM10,RNF103,RTN4,FXR1,GAN" MicroRNA hsa-miR-4276:mirSVR_highEffct hsa-miR-4276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.88E-98 1.62E-94 1.69E-97 1.56E-96 256 1080 "KCNH8,AS3MT,FAM43B,CSMD3,ADCY6,ADD1,CDC7,ERMN,ESYT2,PTCHD1,ADRA1B,HECW2,KIAA1324,OSBPL6,LRRC7,SEMA6A,PCDH10,ANK3,PKP4,GPAM,ALS2,CACHD1,CDC14B,MIER1,SPTBN4,ASPH,NOL4,SEC11C,CALB1,VSTM2A,SPAG9,RUNX1T1,CBFA2T2,DGKI,CDC27,CDC42,LRRFIP1,LGI1,L3MBTL4,SRSF11,CHGB,CHN2,B4GALT6,NRXN1,TPP1,CLTC,VAX2,C4orf33,HECTD1,AKAP7,SLC4A8,ABI3BP,AHCTF1,SNCAIP,VAC14-AS1,APPL1,ST18,ZSCAN23,ARHGAP24,FRMPD4,DAPK1,TOMM20,PABPC5,AIF1L,ZNF804A,ALKBH8,SMG7,FAM107B,HS3ST4,DYNC1I1,ABI1,FAM78B,E2F5,TSPAN5,RASGRP1,OPTN,PHF20L1,MBNL2,CALCRL,USPL1,EIF1,VPS13B,EPB41L2,IGSF6,VPS26C,ADGRV1,EYA1,ZNF461,FABP7,CEP78,SLC37A3,NBEA,TMEM107,HRASLS5,GABRB1,GABRG2,BRPF3,GALC,NCKAP1,GATM,NEU3,TUBGCP4,WASHC2A,GK,DBF4,GPR75,GLS,GLUL,CBX1,RAB40B,FERMT2,GPM6A,GPM6B,CCDC184,NUDT21,STMN2,GRM1,GRM5,GRM7,CIT,RNFT2,WIF1,RASSF8,SMAP1,ATCAY,IDH3B,C2orf72,USP54,LIX1,IL6ST,INPP5B,OLFM3,KIT,STXBP5,NCOA7,MARK1,MBNL1,MEST,MIA2,MID1,AFDN,MOG,NAP1L3,NASP,CCDC13,NNAT,SLC11A2,NTRK3,NUMA1,OPHN1,PAH,PAX6,PCSK1,PDE4B,PDE4D,GPR85,PIK3C2A,FAM216A,PURG,PSAT1,FA2H,CRLS1,RASGEF1B,PKN2,VPS13C,SNRK,WDR25,CNTLN,TMEM260,PTPRE,PTPRG,ZSCAN2,ZNF615,USP47,RAP1GAP,ZMAT4,RGS7,SEC61A2,RIC8B,NUDT11,PNMA8A,ELP2,PCMTD2,SPIN3,ZC3H14,MCMBP,ATP8B4,ACER3,ZNF354C,SATB1,IL17RB,SELL,CPEB3,R3HDM2,NLGN1,PAAF1,WDR37,SLC1A6,KANSL3,RAB3GAP1,SLC20A2,CPEB4,UNC80,CLUAP1,KDM4C,ATP10B,ZNF302,RGL1,DIP2A,FGD4,NUDT10,ADAMTS17,COBL,TACC1,TACR1,DDHD2,MCF2L,DMXL2,RPGRIP1L,WDR7,PCDHGA11,FRYL,CRB1,ITGB3BP,LEFTY2,AP4E1,AKTIP,ARL10,TMOD1,TMPO,NPL,METTL3,TRPC3,ANKRD20A2,TMEFF2,HIRA,CADM1,AMOT,BCL2L13,RICTOR,XRCC4,PCDH20,MICU3,TRIM9,AGMO,PLPP4,DNALI1,PRDM10,ADAMTS9,MPPE1,PDSS2,MARCH8,TRAM2-AS1,TIGD6,MSRB3,FXR1" MicroRNA hsa-miR-1267:mirSVR_highEffct hsa-miR-1267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-98 2.09E-94 2.19E-97 2.02E-96 249 1024 "SYN3,BRAP,SLC12A5,ERMN,KIAA1211,PTCHD1,HECW2,ALAD,SYT13,AMPH,CCDC146,PKP4,APC,MAGEE2,SHROOM2,PPP4R4,TMEM263,ARHGAP5,RGS20,LINC00173,CDK13,ZBTB10,ATP1B3,ATP2B1,MPDZ,SYNJ2,JAZF1,CA8,CALB1,CALB2,CARS,SPAG9,RUNX1T1,CBR1,C1orf52,CCPG1,SRSF11,CHN2,JAM2,CLCN3,HECTD1,ARHGEF6,FAM149A,AKAP6,COL4A5,SLC4A8,SMARCAL1,MFSD4A,HS3ST5,CP,SLC35F1,CLOCK,CSF2RA,CSNK1G3,SOCS5,VAC14-AS1,UBXN2A,PUM1,ST18,USP6NL,CYBB,BOC,ARHGAP32,ZFYVE16,EARS2,LONRF1,ZBTB24,PLEKHM1,HEPH,SV2B,SPOCK3,USP3,CDON,DRD1,ARRDC4,EDNRA,HIPK3,FCF1,PHF20L1,EML1,OLIG2,EPB41L2,EPHB1,ADGRV1,SUCO,AGAP2,ANKFY1,HVCN1,APOPT1,UFM1,STAMBP,ATP2C1,NRG3,STAG2,CHL1,DISC1,GCNT2,PPARGC1A,MALT1,DBF4,LOXL3,GPR22,GRIA1,DIDO1,GRIK3,ZBTB49,SOX21,MAP4K5,CELF3,C9orf129,HSF2,KNDC1,IL6R,IL6ST,DIPK1A,ITGAM,KCNMA1,KCNN2,STXBP5,INSYN2,SYTL4,SMAD9,MAOB,MAP4,MAT2A,MEST,PPM1L,WDR49,ERICH3,MSR1,PABPC1L2A,MYT1,NF1,PCBP3,NTRK3,OPA1,SNTG1,PAK3,PBX1,PC,GNG2,PIK3R1,XRN1,KCTD15,PCDH18,HMGCLL1,TRHDE,RC3H2,ING3,NXPH1,MAPK8,GRAMD1C,PSMD13,PLPPR1,MTMR10,PTPRE,PTPRG,PTPRO,ZNF615,RAD17,ZCWPW1,DBX2,ERI2,RGS3,SLC25A36,RIC8B,RPRD1A,ZNF532,ALG9,GSTCD,ABCA11P,SALL1,SCN2A,SEC14L1,TRA2B,SH3BGR,ITSN1,FERMT1,NTNG1,CHD9,BCAN,ST3GAL3,PREX2,PPP4R3A,RUFY2,RAB3GAP1,ARHGEF40,CCDC88A,ZNF334,RCOR3,KIF13A,UNC80,USP33,MYT1L,BDP1,SP4,IZUMO4,ZNF423,TSPYL2,NPAS3,TAB2,ZNF302,SSTR1,NKAIN2,STAU1,ZSCAN29,AJAP1,FGD4,VPS13A,SYT4,FAM208A,TBL1X,TCF7L2,SZT2,WDR7,TLL2,ERCC6L2,PIK3R5,TPM1,TRIO,TSN,EIF4ENIF1,FLRT2,WIPF1,ZNF17,MICU3,AGMO,MKRN3,LYPD6,ANKS1B,PLPPR5,UPF3A,INTS3,MAP3K12,MFF,PRDM2,LRP8,STOX2,PRDM10,SNX27,FIP1L1,CAB39L,FAM47E,FAM13C,UBE3B,SMIM8,PHTF2,ADAMTSL3,KLHDC1" MicroRNA hsa-miR-125a-3p:mirSVR_highEffct hsa-miR-125a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.17E-98 3.47E-94 3.63E-97 3.34E-96 258 1100 "CLK4,KDM5D,ADD3,ADORA3,KLHL13,RTL9,KIAA1324,CC2D2A,USP35,ABCD2,PCDH10,BBOX1,AMT,SUGT1P4-STRA6LP-CCDC180,ALS2,CADPS,LINC00173,STK33,ATM,TTLL9,ADGRB2,ADGRB3,IL33,DDR1,KALRN,CAST,SPAG9,RUNX1T1,LDB2,CERS5,P2RX6,DGKI,CDC27,NUMBL,CHGB,CHN2,JAM2,NIPBL,ANKRD35,SUMF2,BTF3L4,ZFP28,GDA,SNCAIP,CSF1,SIPA1L1,UBXN2A,PPP6R2,ZSCAN23,DCAF4,DOCK4,ARHGAP24,DAPK1,ARMCX4,C8orf34,ZEB2,B3GAT3,BLOC1S6,LYPD1,SNAP91,NTM,DPYSL2,SLC25A18,DTNA,DTNB,ABCC5,ABCC9,AASDH,FRY,MBNL2,TNK2,PAN3,RABEPK,CDKL3,VPS26C,SIRPB1,ADGRV1,DLC1,ZNF589,FER,MED12L,KIAA1109,FGF11,CAP2,AGAP3,IQCG,APOPT1,STAMBP,NPTN,ATP6V1H,NSG2,NSG1,OGA,FYN,GABRA2,B4GALNT1,ERAP1,MYOZ2,GATM,NEU3,TNRC6A,GNAS,GPM6A,CECR2,PRDM5,SOX21,GYG1,PACSIN2,TNFAIP8L3,LINC01102,ELOVL5,HPSE2,HNMT,ZDHHC15,TCEAL6,HTR5A,MSL1,FAM95B1,IGSF1,SCIN,IL6ST,ITGAV,JAK1,GPR62,KIF2A,STMN1,HECTD2,NCOA7,LSS,MAN2A2,MATN3,MBD1,LRP1B,MOBP,MYO9A,NF1,NFE2L2,CNOT4,NPPA,NUMA1,ODF2,P2RX7,ZNF827,GLIPR1L2,SNTG1,ETFRF1,PCDH8,PDPK1,SEMA5B,A2ML1,CCSER2,FAM216A,RC3H2,LRP12,PRRX1,SH3KBP1,PKIA,RAB39A,MAPK9,HYDIN,KLK6,BCAS3,SNRK,PTCH1,ANKHD1,PTN,OCIAD1,PTPRE,PTPRZ1,RADX,MSANTD2,SLC6A15,ERI2,RGS4,RIC8B,RNH1,ELP2,ABCA11P,HSD11B1L,RTKN,KCNIP1,SEMA6D,SATB1,TNFRSF19,FOXRED1,SGK1,SH3GL3,SHC4,MAGI3,ST6GAL1,SLITRK3,NLGN1,SLC1A3,DHX30,RUFY2,SLC8A1,RAB3GAP1,BTBD7,SMARCE1,MBD5,PALLD,UNC80,ZSWIM8,EMC1,RBM26,NPAS3,LMO3,POGZ,EPB41L3,LARP4,SSPO,MPRIP,RGL1,GANAB,COBL,C12orf76,POPDC3,FAM208A,SIN3B,ZFP90,CUX2,ZEB1,SIK3,ITGB3BP,HHIP,SEZ6L,C9orf85,ELP5,PDSS1,AMACR,ZKSCAN5,TUBB2A,FAM155A,UGT8,TOM1L2,MEAF6,WIPF1,KLC2,TRIM9,LYPD6,ANKS1B,SMARCAD1,CA10,MAP3K12,CADM2,PARP6,GDPD5,PCDH15,NAV3,LINC00632,WNK2,RGS7BP,MRPL47,UBE3B,TRAM2-AS1,FXR1,ST8SIA2,SLC4A10" MicroRNA hsa-miR-1236:mirSVR_highEffct hsa-miR-1236:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.48E-98 3.64E-94 3.80E-97 3.50E-96 279 1279 "NCKAP5,ACTN1,METAP1D,NDRG2,SLITRK1,ADCY6,ADD2,PLEKHH1,KIAA1211,BEND6,NLGN4X,SLC24A4,SNX32,HECW2,ZNF578,CEP126,LCORL,PPFIA1,UPRT,CACHD1,API5,PPFIA3,TMEM263,ASPH,BRINP2,NCOA1,ALDH7A1,ATP6V1G2,ADAM23,DCAF5,KSR1,DDR1,KALRN,CAMK2G,CDC27,MAGI1,CDO1,CCPG1,CHN2,CASC2,JAM2,NDST3,CLCN3,KIAA1549L,CLU,MYL6B,CNR1,FAM149A,WHRN,COL11A2,AHCTF1,SMARCAL1,HS3ST5,CHD1L,TRIM69,MICAL2,SIPA1L1,CFAP61,NRSN1,DCAF4,BOC,KIAA0586,ARMCX4,ELMO1,ZC3H11A,ALKBH8,RHOBTB1,SMG7,DLG4,RAB39B,PDCD6IP,ECM2,ABCC5,DNM1L,FAM135B,EDNRB,HIPK3,SEMA3D,RBM12,YAF2,PHF20L1,MBNL2,ABI2,SORBS3,TMEM35A,PAN3,EPB41L2,DENND4A,F5,CACNG3,TAOK3,DLC1,CHST15,TOMM40L,ZSCAN30,STRADA,FDFT1,TESK2,POLR1B,FGFR3,SUCO,ATP13A4,SLC37A3,ZNF605,CGREF1,AP4B1,STAG2,HRASLS5,CHL1,ARPP21,ZNF234,NCKAP1,C15orf41,GCNT2,TUBGCP4,SULT1C4,CRCP,PCDH11X,STARD3,ZNF638,INSM2,PSRC1,GPM6B,TDRKH,GRIA1,GRIA2,GRIK2,GRM1,CIT,LINC00839,GSTM5,KAT7,RNFT2,CELF3,UBE2QL1,NXPH2,ATXN2L,HMGB1,SMAP1,IRF8,MSL1,GAREM2,TJAP1,SCIN,IL6R,BRINP3,ZNF678,OLFM3,CDH20,KCNC2,KCNJ3,TTYH2,LAMA2,SYTL4,PACRG,LOC100128239,MBD1,MEIS2,MOG,ZNF92,CTNNA3,NCAM1,VWA2,NTRK3,OCRL,OPHN1,PAX6,PCSK5,PCSK2,PDE4D,PDGFRA,GNG2,HERC2P3,NLGN3,FAM218A,JAKMIP1,PLP1,PLXNB1,MAPKAP1,PRRX1,ING3,MINDY2,TATDN3,PPP2R5C,GRAMD1C,BCAS3,GDPD2,BDNF-AS,PTPRG,FAM120C,PPP2R3C,C1orf54,FAM184A,RASGRF2,RDX,GAL3ST4,ERI2,RFX4,RFX5,UBR7,SETD5,ROBO2,ELP2,FBXW7,ZC3H14,ATP8B4,TMEM156,SCN2A,SELL,ZFP30,DOCK10,SHC4,FBXO11,ST6GAL1,SYBU,ABLIM3,EPN2,SMTN,RUFY2,RAB3GAP1,NAPB,SMARCE1,RCOR3,SNRPN,PDZRN3,BDP1,ZSWIM8,KDM4C,RBM26,NFASC,TAB2,POGZ,ZC4H2,SS18,NXT2,ZSCAN29,ARHGEF9,FNDC9,TACR1,UNC5D,TCF4,SIN3B,TCF7,ZEB1,NSD1,PUM2,HIF3A,RNF216P1,ZNF106,FBXL16,ASXL3,ERCC6L2,HEY2,TPM1,ZNF384,PRMT8,ANKRD20A2,CADM1,FAM155A,UBTF,FLRT1,PLEKHH2,NSD2,CLDND1,ZNF708,TRIM9,NDRG4,SYNC,UPF3A,STMN4,ADAMTS9,PCDH15,RGS7BP,UBE3B,PAK5,KAT6A,ZNF248,DPF3,SRGAP2B" MicroRNA hsa-miR-3144-5p:mirSVR_lowEffct hsa-miR-3144-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.82E-98 5.52E-94 5.76E-97 5.30E-96 246 1004 "ASPHD1,EMILIN3,GPRIN1,TMCC3,RNF157,ADD1,SLC12A5,KIDINS220,NLGN4X,PLA2G6,PCDH10,UNC79,LRFN1,API5,MIER1,SPTBN4,ARNTL,PDE8B,DACT3,PCDHGB4,CHID1,ATP1A2,ATP2B3,CADM3,DNAJC27-AS1,CACNA1D,CACNB4,CALB1,CALB2,CABP7,KALRN,TRIM41,SHISA7,ZMYM4,NOG,CASC2,NDST3,EPS15L1,NRXN3,PPT2,STOML1,FHL5,IQCK,COL9A2,LETMD1,TBPL1,TOGARAM2,MYRIP,CLIP3,PLCH2,SOCS5,RUBCN,ZNF337,SPOCK2,KIAA0319,ZC3H11A,SV2B,DLG2,TOM1,ABCC9,EDNRA,CNNM1,EIF4G2,ANKRD13B,REEP2,ZIC4,CORO2B,FGFR1,FGFR3,IP6K2,FOXM1,SEMA4D,NOP56,ARFGAP2,ATP2C1,ERGIC3,KBTBD12,TPPP3,TMEM151A,FYN,JPH4,ZNF274,IP6K3,SIGLEC8,GFER,GGT7,KIRREL3,GLI2,GRB10,PRDM5,RNF165,FAM107A,UBE2QL1,MAN1B1,SYNPO,HMGCL,HPCA,ZDHHC15,MSL1,TJAP1,ZNF678,DIPK1A,GPR62,KCNJ3,KCNJ11,KCNK3,KCNMA1,CREG2,KLC1,STXBP5,L1CAM,PAXBP1,ASPRV1,MAP6,MEIS1,KCTD6,MMP17,GIT1,PTOV1,MT3,MYH6,MYO7A,NCAM1,NNAT,CNTN3,PC,PCDHGC3,ZDHHC8,GDAP1L1,KCTD15,PLCD1,PLIN1,SLC25A23,MTRF1L,PLXNB3,PNMA3,C11orf49,POLR2F,FSD1,MED1,KANSL1,MAPK4,MASP1,SIDT1,PTPRE,PTPRN,FAM120C,PYGM,TTC13,IQSEC3,UBR7,PRIMA1,RLBP1,MYH14,PNMA8A,RPE,SNX22,ATP8B4,GLDN,RYR3,ATXN2,LINC00461,ASIC4,FNDC3A,FHOD3,WDR37,ZNF365,RPH3A,SLC6A7,SLC6A9,SEPHS1,SLC9A5,EFHD1,NAXD,MAST1,MBD5,KIF13A,CABCOCO1,SNRPN,TMCC1,UNC80,PDZD2,WDTC1,FNBP1,IZUMO4,KIF1B,TSPYL2,NPAS3,DDN,ST5,AJAP1,SUPT5H,SLC37A2,KAZN,EXOC7,VWA3A,TCF7,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,SYNE1,NAT16,PCDHGA1,PHF24,AKNA,SIK3,CYB561A3,CRB1,SPX,C18orf54,ERCC6L2,LRRC8A,RASD2,ZNF384,SYNPO2,CLEC2L,MTCH1,LAT2,NSD2,NPDC1,RICTOR,ZFP41,ZBTB16,TMEM198,EML6,PLPPR5,SYNC,MEIS3,GDPD5,HPS4,SEMA3B,URM1,WIPF2,MARCH8,PHTF2,CASC15,VANGL2" MicroRNA hsa-miR-125a-5p:mirSVR_lowEffct hsa-miR-125a-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-97 8.56E-94 8.93E-97 8.22E-96 305 1517 "ABAT,ACADM,ACHE,SYS1,NDRG3,PLEKHG5,ADD1,ERMN,LRFN2,BEND6,MTUS1,SNX32,RTL9,TXNDC16,CC2D2A,MARCH4,AMPD2,PI16,PKP4,KCNAB2,APC,DGKZ,UPRT,TNRC6C,API5,AQP6,SPTBN4,SLC4A4,SLC2A11,DOCK11,SNAI3-AS1,CFLAR,KSR1,SYNJ1,SCAPER,CACNA1B,CACNA1E,DDR1,DIRAS1,ISPD,ARHGEF1,SCARB1,ENTPD6,ARHGEF2,DCLK1,L3MBTL4,CBARP,CASC2,RAB33A,RAB28,KIAA1549L,NRXN1,FADS2,DNAJB5,ARHGEF6,ANKRD35,SUMF2,MYRIP,MFSD4A,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,TENM4,SIPA1L1,NCAN,APPL1,CMTM5,CTH,GREB1,FAM131B,ECE2,NOS1AP,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,PLEKHM1,HEPH,CNIH3,RUSC2,COPS7A,ZC3H11A,SV2A,RPS6KL1,DPH1,RCAN1,DTNA,DTNB,ABCC5,FAM135B,PHC2,SYT15,CNNM1,PHF20L1,TMEM132E,PLEKHA1,ANKRD13B,MRPL10,ANKMY1,SCML2,FCGR1A,STRADA,ZNF589,FER,PRKAG2,SMC2,ARFGAP2,DACH2,GPR153,HHIPL1,AP4B1,NRG3,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,USP19,GGT7,CRCP,TCERG1,GLS,ZNF638,LOXL3,GNAS,GOLGB1,LILRA2,CCDC184,LPAR4,TMEM121B,CECR2,PCLO,RAPGEF4,GRB10,GRIA2,SPACA9,RASSF8,PADI2,PTGDR2,MAN1B1,HRH3,TNFAIP8L3,SYNPO,HMGCR,HNF4G,OPALIN,NKD1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KCNA1,KHK,KIF5A,KIFC3,SYTL4,HECTD2,LSS,MAP2,MAP6,ADAM11,MIA2,MOBP,MSI1,C10orf105,MYO7A,NEFM,NUCB2,IGSF11,DPY19L2P2,PDE3B,PDGFRA,ZDHHC8,CAMKV,ZNF655,RETREG2,POLG,POU3F2,MINDY2,PTPA,PPP2R5C,PRKCZ,MAPK10,PROX1,VPS13C,PSMD13,CNTLN,PTH1R,PTK2,PTPRD,PTPRE,C1orf109,FAT4,ARID4A,ZDHHC14,SLC6A15,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,SNX22,STK32B,EMID1,LRRK2,MEG3,SCN2B,SCP2,ASIC4,CASC3,ITSN1,KIF16B,MYO18A,MAGI3,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,SLCO1A2,LGI3,ABTB1,SMARCA4,ANKRD36,SNRPN,UNC80,DOP1A,WDTC1,MYT1L,KIF21B,ENKUR,GLT8D1,CAND2,ZC3H13,SPTB,NFASC,SS18,SSPO,NCDN,ELOVL4,ADHFE1,FAM168A,FGD4,SYN2,SLC37A2,TACR1,TMEM136,SATB2,TCF7,RPGRIP1L,WASHC4,TF,PMS2CL,DICER1,CRB1,GPR161,AKTIP,BHLHB9,LRRC8A,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,FLRT2,BCL2L13,PORCN,ELFN1,GPR158-AS1,CRB2,LYPD6,TMEM198,EML6,PRDM2,CSDE1,STOX2,ADAMTS9,SEMA3B,PCDH15,SLC17A7,CAB39L,WIPF2,PLSCR4,PARP11,GOPC,UBE3B,TMEM63C,ZNF248,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-498:mirSVR_highEffct hsa-miR-498:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-97 1.42E-93 1.48E-96 1.37E-95 244 992 "ADAR,ADD1,BRAP,SORCS1,MTUS1,OSBPL1A,WDR35,LRRC7,ALCAM,MARCH4,FAM135A,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PKP4,ALS2,BCAS1,CDK13,NCOA1,NUMB,ATP2B1,BACH1,SYNJ2,NAE1,BTK,SGCE,C5,OSGIN2,WASF1,CACNA1A,CACNA1E,CACNB2,CACNG1,VXN,CAST,SLC16A4,TMEM257,CCPG1,CHM,RAB28,IQCK,AKAP6,BTF3L4,LETMD1,AHCTF1,MFSD4A,CHD1L,RBM39,RNF14,CSF2RA,PDE4DIP,DZIP3,NRSN1,RUBCN,DOCK4,KATNAL2,RIPOR2,TOMM20,PABPC5,ZEB2,HP1BP3,RHOBTB1,PLPPR4,SV2B,ARNT2,GRIN3A,DMD,HS3ST2,GNE,DTNA,DTNB,FAM135B,EDN3,ATL1,RASGRP1,ELAVL2,ELAVL4,PAN3,STX2,RTN3,EYA1,ACSL4,KIAA1109,FGF1,AMOTL2,PRKAG2,MEX3B,SLC37A3,SMC2,RASL10A,CELF1,CSPG5,SARAF,DKK3,MEGF10,HRASLS5,DISC1,GATM,MALT1,COPS8,DBF4,SPIN1,TNRC6A,FERMT2,EML4,GRIA2,NR3C1,FAM19A2,LINGO1,GUCY1B1,WIF1,HAS2,GABARAPL2,HNF4G,DHX35,IRF8,MSL1,RBPJ,DOCK7,SCIN,ZNF678,INPP1,LRRTM3,ITGAV,KCND2,STXBP5,VWA5A,HECTD2,SMAD1,MAP4,MARK1,MATN3,LRP1B,MEIS1,KITLG,MOBP,MYBPC1,NAP1L3,NCAM2,NCF2,HCN1,OLR1,OPA1,PAH,DPY19L2P2,PCDH9,PDE4B,PIK3R1,CCSER2,XRN1,PCDH18,PURG,PPM1B,CRLS1,PPP2R5C,PPP3CA,KANSL1,PRKACB,CEP41,MAPK9,GRAMD1C,RELN,SNRK,PTPRE,PEX2,TTC13,RAD52,OXR1,SLC6A15,ZYG11B,ERI2,PBRM1,ZNF532,EXD2,GSTCD,ADAL,MIR124-2HG,LRFN5,SCN2A,LRRTM4,SCP2,HES6,TNFRSF19,ELMOD1,SLC30A10,ITSN1,HKDC1,FNDC3A,ST6GAL1,NLGN1,ST3GAL3,BTBD3,WDR47,FAM214B,PKNOX2,BTBD7,MYH15,RIMS1,SNAP25,MBD5,PALLD,UNC80,TRERF1,BDP1,KIF1B,LMO3,C11orf87,ITPRID2,ZNF302,LARP4,NKAIN2,SEPT8,COBL,ANKRD28,C12orf76,TACC1,MTCL1,CAMTA1,TAF9,SIN3B,NAT16,FAM200B,DICER1,AP4E1,MTMR14,ACTR6,C5orf64,TNNT1,TP53BP2,SEZ6L,PRMT8,AMACR,TRPC3,RPRM,PITPNB,BCL2L13,XRCC4,PCDH20,ZNF28,KCNT2,TMEM237,ANKS1B,WNK1,CADM2,PRDM2" MicroRNA hsa-miR-3202:mirSVR_highEffct hsa-miR-3202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.29E-97 2.41E-93 2.51E-96 2.31E-95 255 1084 "ABR,ADCY6,NLGN4X,OSBPL1A,FAM135A,OGT,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,GPAM,ALS2,MIER1,DACT3,ZBTB10,STX16,N4BP2L1,ATP6V1G2,PROM1,CDK5R1,SYNJ2,SCAPER,WASF1,CACNB4,KALRN,CAMK2D,TRIM41,CBLN1,CCKBR,CERS5,SYNGR3,CD38,CDC42,CHGA,PLEKHB1,TAOK2,EPS15L1,PPT2,NRXN2,CLTC,ABCG2,QKI,SLC4A8,CP,CPS1,CRMP1,MYADM,ARHGAP24,EARS2,ZNF337,KIAA0586,PHYHIP,SPOCK2,SPATA2,ZEB2,B3GAT3,HP1BP3,C2CD2L,POM121,SMG7,SV2A,KIF19,GRIN3A,DNM1,HS3ST4,DNAH9,DRD1,FAM78B,DYRK1A,EDN1,FCF1,CNNM1,EFNA3,ING4,CALCRL,HSD17B14,VPS13B,EPHB1,SPEG,CDHR1,MRPL10,ETV1,RASL12,ZNF461,PTK2B,TAOK3,DLC1,TESK2,GTF2IRD2,FHL1,STAMBP,USP21,CAMKK2,ATP6V1H,GABBR1,HRASLS5,ZMYND11,JPH4,GAP43,GGT7,RUNDC3A,GLYR1,RAB30,PCDH11X,KDM2B,GNAS,GP1BB,CNDP1,CCDC184,MCHR1,CECR2,PLCD4,GRIK2,GRIN2D,GRM7,KAT7,RABL2A,ATXN2L,ARHGAP36,SYNPO,ITGA7,ITPKA,OLFM3,GPR62,KCNJ3,STMN1,FGFBP3,MAP4,MBD1,KCTD6,MN1,CD200,MRPL42,BLOC1S2,ADAM22,N6AMT1,MXI1,NDUFA5,NF1,NNAT,NOVA1,NPR2,NRGN,NTRK3,NUCB2,OLR1,PDE4A,PDGFRA,BEST3,GDAP1L1,PLP1,PURG,PMP2,EPB41L4B,POU3F4,MAPK4,EPDR1,KLK6,APTX,SIDT1,MDGA2,CNTLN,PTK2,PTPRD,RAB5B,FEZF2,VEPH1,TRIM68,DPF2,RNF220,NUDT11,ZNF532,SETD5,CARF,NEK11,ARMH4,ATP8B4,ATAT1,RTKN,RXRG,FAM192A,FNIP1,COPZ1,SH3GL2,FRMPD1,NTNG1,SHMT2,CHD9,ZNF365,RPH3A,DHX30,SMTN,WDR47,FAM214B,RAB3GAP1,CCDC88A,ELMO2,SMARCA4,RIMS1,SON,ZC3H13,LMO3,COLGALT2,STOX1,VAMP1,SYN2,ANKRD28,TACC1,MLST8,FBXW11,TCEA1,CUX2,TCF12,CLASP1,TMEM151B,USP32P1,TF,THRA,TIAM1,ZFP91,PRRT1,R3HDM1,CSMD1,KAT6B,TNR,TPM2,TPM3,ELP5,ZMYND8,KCNE5,TSN,SGK3,CADM1,SLC35A4,PITPNB,OSBP2,FLRT2,BEST1,WIPF1,CLDND1,RICTOR,XPO1,SF1,ZIC2,EML6,PRDM10,PCDH15,NAV3,SNX27,FIP1L1,MARCH8,UBE3B,RNF170,VANGL2,KLHDC1" MicroRNA hsa-miR-582-3p:mirSVR_highEffct hsa-miR-582-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-97 2.88E-93 2.99E-96 2.76E-95 243 987 "SDE2,NCKAP5,KDM5D,RTL9,OSBPL6,C1QTNF3,PCDH10,EP400,LCORL,PARG,ALS2,SHTN1,MIER1,CASK,TMEFF1,ARHGAP5,ASCL1,TMEM108,ATP1B3,N4BP2L1,DPY19L3,LINC00847,SEC11C,DCAF5,ARHGEF7,OSGIN2,PTBP2,SLC25A14,SYT6,NFS1,SEPT7,CDH10,SYNPR,FAM19A5,DNAJB5,AKAP7,IQCK,GAL3ST1,COX4I1,CP,C2CD2,HAPLN1,CRYM,SEC24C,MICAL2,CSNK1G3,FAM169A,UBXN2A,CTNND2,DOCK4,HDAC9,TCAF1,ARHGAP24,ZFYVE16,EARS2,LONRF1,KIAA0586,PABPC5,DBI,GIT2,SPATA2,ELMO1,MFAP3L,HP1BP3,CEP170,LYPD1,DDX46,ALKBH8,SACS,DLG2,USP3,DOCK2,DPH1,ACOT8,E2F5,FSD1L,EFNB3,FAM13A,ABI2,C8orf37,DCTN4,EPB41L1,SRRM1,DNAJC27,SCML2,CEP78,ATP13A4,NBEA,DACH2,ST6GALNAC3,CSPG5,STAU2,TBR1,OGA,DKK3,GABBR1,GABRA2,CAB39,BRPF3,FAM120B,ARPP21,GAP43,SULT1C4,WASHC2A,PCDH17,CRCP,COPS8,TNRC6A,FERMT2,GPM6B,GRIK1,GRIK2,GRIK4,CIT,KIF3A,BVES,IRAK3,ATXN2L,TNFAIP8L3,MIER3,HMGCR,HNF4G,RAB41,RBPJ,IGSF1,ZNF678,KCNA6,KIF2A,KLRC2,HECTD2,NCOA7,SMAD1,PIK3AP1,MAOB,MAP4,MARK1,MARK3,MATN2,MBD1,PPM1L,RSPO2,MYT1,NF1,NUMA1,GPR88,GLIPR1L2,PCSK2,PDE4B,PDPK1,PDYN,FAM98B,CDK14,CAMKV,A2ML1,PLCL1,PDZRN4,MAPKAP1,SPATA6,MAPK9,GRAMD1C,HYDIN,PTPRB,C1orf109,PTPRZ1,TTC13,ZNF615,CCDC40,RAP1GDS1,ENOX1,OXR1,RGS7,PBRM1,CARF,NEK11,SPIN3,MAP6D1,LRRK2,CNTNAP3,CLIP1,NCBP3,SCN2A,TNFRSF19,PPP1R9A,SHC4,MAGI3,CHD9,NLGN1,PAAF1,SLA,FAM81A,WDR47,SLC6A1,CPEB4,KIF13A,SNRPN,UNC80,DOP1A,NMNAT2,UHRF1BP1L,ZBTB43,C11orf87,PBLD,CLASP2,TROVE2,ZSCAN29,RGL1,SULF2,KLHL7,PRRC2C,EHBP1,GPRIN3,FRYL,BHLHB9,BEX4,R3HDM1,TPM4,WBP2,ZNF384,TSN,SGK3,CADM1,PLEKHH2,WIPF1,NSD2,XPO1,ZNF23,KCNT2,ZNF138,SPIRE1,FTSJ1,SMARCAD1,SYNC,DHX33,CA10,EMSY,PRDM2,CSDE1,NAV3,GOPC,PHTF2,FBXO36,SLC4A10,FAM198A" MicroRNA hsa-miR-143:mirSVR_highEffct hsa-miR-143:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.02E-97 4.50E-93 4.68E-96 4.31E-95 269 1205 "KCNH8,ACTN2,GALNT16,ADD3,KIDINS220,AP2A2,KLHL13,WDR35,ZNF578,FGD2,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,RGS20,NUMB,ZNF583,SLC2A11,ATP6V0A1,AZGP1,SEC11C,SCAPER,GYG2,CACNA1A,THSD7A,CALM1,PTBP2,VSTM2A,CAST,SPAG9,INA,CBFA2T2,LRBA,DCLK1,TIGD7,SRSF11,CHM,CASC2,ZBED5,RAB28,PPT2,QKI,AKAP6,COL4A5,COL9A2,COL11A2,SLC4A8,CHD1L,FAM171B,SEC31B,PREPL,RBM39,RNF14,GDA,OSBPL3,CSNK1G3,ATRNL1,VAC14-AS1,CTH,CTNND1,NRSN1,CYBB,DOCK4,HDAC9,ARHGAP32,KATNAL2,DCAF8,ZFYVE16,EARS2,DAPK1,DNAJC6,ZEB2,ELMO1,TMEM130,DDX46,DOCK2,DMTF1,ARRDC4,DTNB,ANKRD46,SGK2,COPS4,PAN3,SRRM1,CDKL3,CLVS1,FAM198B,DLC1,FDFT1,SLC9B2,FGF1,UBE2E3,FOXG1,SYT3,SMC2,TPK1,STAU2,PNMA2,GABBR1,HBS1L,AHCYL1,ZMYND11,GALC,DISC1,WASF3,GATM,GHR,PPARGC1A,COPS8,GLDC,ZNF638,PRUNE2,PCLO,ZNF496,KAT7,AP4S1,MAEL,ZHX1,HMGCL,LINC00667,PLD5,USP54,IL6ST,IL11RA,ZNF678,JAK2,KCNC1,KCND1,KCND2,KCNK2,KCNMA1,STXBP5,INSYN2,NCOA7,ERICH3,MYO5A,MYO6,MYO9A,NCAM1,NDP,NEK1,NODAL,CNOT4,NTRK2,OPA1,OPHN1,GLIPR1L2,SNTG1,PC,PCMT1,PDE1C,PDGFRA,PDYN,BEST3,OLA1,GPSM2,PLIN1,STRN3,LRP12,PPP2R5C,RASGEF1B,MAPK7,MAPK9,SIDT1,CNTLN,BDNF-AS,TMEM260,PTPRB,PTPRD,PEX2,CEP97,RAD51D,SH3TC2,RASGRF2,RDX,RFX4,KCTD17,SETD5,TMLHE,CARF,ROBO1,ARMH4,ADAL,STK32B,PTGR2,ZNF354C,FAM192A,LRFN5,HOGA1,ELMOD1,SELL,FOXRED1,SCAF8,ZFP30,FERMT1,ASAP3,CTXN2,ANKRD6,SLC1A3,FAM81A,SLC6A9,SLC12A4,ELMO2,TET1,EPC1,CDK5RAP2,LIMCH1,SNRPN,UNC80,KDM4C,ZBTB43,ATP10B,TROVE2,STXBP1,KLHL7,SYT11,NUDT10,PLCB1,SYN2,ANKRD28,C12orf76,ANKRD12,TRIM2,WASHC4,WDR7,PCDHB10,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,HHIP,TIAM1,MTMR14,RELL2,ERCC6L2,TMPO,NPL,TPM3,HSPBP1,ZNF610,FAM155A,DNAJC12,MEAF6,TBC1D15,NSD2,KLC2,ZIC1,ZNF28,TRIM9,MKRN3,FSTL5,FTSJ1,MEIS3,UPF3A,WNK1,CADM2,LINC02210,HPS4,URM1,SLC17A7,PDSS2,CAMK1G,NLRP3,RNF170,NETO2" MicroRNA hsa-miR-557:mirSVR_highEffct hsa-miR-557:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.21E-97 4.61E-93 4.78E-96 4.40E-95 242 981 "KCNH8,ABHD6,ACTN1,FAM43B,ERMN,PWWP2A,ADRA1D,OLMALINC,ZNF608,HACE1,ALCAM,BCAR3,ABCD2,UNC79,AMPH,ZFAT,ANK2,USP28,PPFIA2,CNIH2,PPFIA1,ALS2,NCOA1,ATP2B2,B3GALT2,DOCK11,TTLL9,BACH1,BCL7A,SYNJ1,JAZF1,CACNB2,CANX,PRC1,CCK,TMEM257,DGKI,LRBA,CDH2,ZMYM4,LOC730101,MAGI1,CHGB,B4GALT6,RAB28,CLCN4,NRXN1,CLTC,IQCK,ARMC8,AKAP6,BTF3L4,SLC4A7,SLC4A8,MYRIP,SEC31B,ARHGEF10,PLXNA4,DZIP3,ERC2,PHF14,RIMS2,HDAC9,RIPOR2,LONRF1,KIAA0586,GIT2,ELMSAN1,ZEB2,KIAA0753,LYPD1,RHOBTB1,SPOCK3,G3BP2,ABI1,ATN1,DSCAM,MAMLD1,DNAJB6,DYRK1A,ABCC9,EDIL3,WDPCP,ANKRD46,CNNM1,KLHL5,GPR61,PHF20L1,KMT5B,EIF4G2,EIF5,ELAVL4,RGS17,PCOLCE2,DCTN4,EPHB1,DLC1,MED12L,FHL1,FLT1,C2orf88,POMT1,SMC2,CAMKK2,KHDRBS3,NSG1,STAG2,GABRA2,GABRA3,C15orf41,GATM,TUBA8,AHDC1,PCDH17,DHRS4,GLS,PCLO,GRIK2,NR3C1,LINC01551,BACH2,HMGCL,HNMT,HNRNPK,MSL1,IDH3A,ZIC5,LRRTM3,SLC35G1,OLFM3,KCND2,KCNJ3,KCNJ9,KCNK1,STXBP5,TTYH2,LAMP2,HECTD2,FGFBP3,MAP4,MARK3,MATN2,MATN3,MEIS1,MIA2,MOG,COL28A1,SESN3,ADAM22,NELL2,NEUROD1,NKX2-2,NPTX2,NTRK2,NTRK3,OXTR,PAX6,PCDH9,PCSK2,ING3,PRKCZ,MAPK9,HYDIN,MDGA2,CNTLN,TMEM260,PTPRD,PTPRO,STRC,USP47,PLEKHB2,DBX2,REV3L,PCMTD2,FBXW7,STK32B,LRRK2,SEMA6D,ATXN7,SCN3A,LRRTM4,TNFRSF19,SELL,COPZ1,FERMT1,CHD9,SLC1A6,PPP4R3A,DHX30,KANSL3,RAB3GAP1,EFHD1,ATF7IP,TET1,DMRTC1,SMARCE1,RCOR3,LMBRD1,UNC80,SP4,HECW1,SRPK2,NXT2,SEPT8,SYT11,ZC3H4,ADAMTS17,ANKRD12,FAM208A,AGTPBP1,ANO4,DMXL2,ZFP90,SYNE1,FRYL,TEK,ITGB3BP,HEY2,RBFOX2,RGMB,RFTN2,PRR18,FAM155A,UBE3A,AMOT,MEAF6,VIPR2,XRCC4,CFAP298,ZIC1,ZNF540,FMN2,ZNF154,SIGLEC10,PDSS2,AMN1,UBE3B,FBXO36,RNF170,SLC4A10,SPATA13,SENP7" MicroRNA hsa-miR-1276:mirSVR_highEffct hsa-miR-1276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.24E-97 4.63E-93 4.80E-96 4.42E-95 263 1154 "SDE2,ABAT,NCKAP5,ADCY6,KIDINS220,INTS2,KLHL13,KCTD16,HFM1,LRRC7,SEMA6A,ALCAM,ABCD2,ARHGAP20,AMPH,DPP10,MAP4K3,USP28,PARG,APC,APLP1,GPAM,MIER1,DDX3Y,ATP2B1,N4BP2L1,CFLAR,BMP7,SYNJ2,ARHGEF7,FUBP1,MTMR3,LURAP1,KALRN,SPAG9,RUNX1T1,CBR1,CERS5,CDC27,MAGI1,NUMBL,TPP1,QKI,TMEM184B,SRP14-AS1,AKAP7,AHCTF1,CNRIP1,HS3ST5,RBM39,HINFP,CSF1,MICAL2,CSNK1G3,ATRNL1,VCAN,PDE4DIP,PHACTR3,APPL1,CTNND2,ARHGAP32,ZFYVE16,TOMM20,PABPC5,C8orf34,ZEB2,MYEF2,KIAA0319,POM121,RHOBTB1,SMG7,SV2B,G3BP2,KIF19,CHRDL1,DLX1,MED12,DTNA,DTNB,ABCC5,EDNRA,ANKRD46,SEMA3D,FAM13A,KMT5B,STARD3NL,KCNMB2,TMEM74,F8,ABCA8,GORAB,MED12L,PRKAG2,FHL1,RGPD5,SLC37A3,SORBS1,SMC2,CELF1,PNMA2,SDCBP2,PHYHIPL,ZNF44,GABRB1,TRAF3IP2,BRPF3,ERAP1,KIAA1841,DNER,ARFIP1,PPARGC1A,KIRREL3,SPIN1,GLS,TOX3,TNRC6A,DCLK2,PRRC2B,PRUNE2,GPM6B,PCLO,RAPGEF4,GRB10,GRIA1,GRID1,GRM5,GRM7,FAM19A2,AP4S1,NXPH2,HNRNPK,IRF8,MSL1,ITGAV,KCNK2,KCNN2,ZNF667-AS1,MARK1,MAT2A,LDLRAD3,LRP1B,MITF,AFDN,MOBP,ERICH3,ZNF92,MYBPC1,NCAM1,NEK1,NF1,OTOGL,NOVA2,DNHD1,SLC11A2,NTRK3,OCRL,OPHN1,CLDN11,PBX1,PCMT1,PDYN,PENK,OLA1,SERPINE2,ST8SIA5,PLIN1,SLC25A23,ING3,EPB41L4B,NXPH1,PPP2R5C,PRKACB,GRAMD1C,SYTL2,SIDT1,WDR25,PIGG,PLPPR1,PTPRD,OXR1,ZMAT4,RNF220,LGI2,CARF,GSTCD,RORB,TMEM206,ADAL,LRRK2,ATAT1,CLIP1,ZNF354C,TRAPPC13,LRRTM4,SCP2,SELL,RASA3,KIF21A,ITSN1,MAGI3,SYBU,SEC31A,KANSL3,KBTBD4,TET1,SLIT1,CPEB4,SMARCE1,TTC17,KDM4B,SON,CDK19,LMO3,ZC4H2,MPRIP,NECAB1,SYNE2,NUDT10,SYT1,FAM208A,UNC5D,FBXW11,SYNE1,ARHGEF12,PUM2,SIK3,SIRT1,ITGB3BP,ZFP91,HEY2,RGMB,TRIO,PPIL6,TSN,HSPBP1,SGK3,UCHL1,CCDC14,WIPF1,ZFP37,ZNF28,CELF4,PLPPR5,DHX33,WNK1,EMSY,CADM2,LRP8,RNF103,ADAMTS9,NAV3,WIPF2,WNK3,RGS7BP,KAT6A,PHTF2,ADAMTSL3,TIGD6,VANGL2,FRMD6,NETO2,GAN,SENP7" MicroRNA hsa-miR-873:mirSVR_highEffct hsa-miR-873:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.03E-96 5.79E-93 6.00E-96 5.53E-95 243 990 "SDE2,TMCC3,PLEKHH1,KIDINS220,NLGN4X,ZNF608,HECW2,LRRC7,SMIM17,FAM135A,MRTFA,BIN1,ZFAT,LCORL,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ALS2,ZFYVE28,ATM,ATP2B1,SEC11C,BCL7A,LDHD,BMP7,ARHGEF7,AP1M1,C5,CACNB2,CAST,CDC27,NOG,CHM,CHN2,CASC2,NRXN3,ZFYVE9,ABCG2,CNGA3,TMEM155,IQCK,COL9A2,ACBD5,MYRIP,CNRIP1,HS3ST5,CHD1L,SEC31B,CDC42BPB,HINFP,GDA,SEC24C,ATRNL1,PDE4DIP,CTH,CFAP61,NRSN1,CX3CR1,GPRASP1,MYADM,ZFYVE16,MATR3,ZEB2,ELMO1,DDX46,DLG2,DMD,DNAH9,MAMLD1,E2F6,YAF2,MBNL2,RGS17,BSCL2,TMEM35A,PAN3,GPHN,RTN3,SIRPB1,NRN1,ABCA8,ACSL4,TOMM40L,FHL1,SYNCRIP,RGPD5,JKAMP,TACC2,NPTN,PRELID3A,ST6GALNAC3,NRG3,OGA,GABRA1,GABRG2,RAPGEF6,DISC1,AHDC1,GLI2,GLS,ZNF638,GRIK2,GRM2,RNFT2,HRH3,HNRNPK,ZDHHC15,TCEAL6,HSPA1L,IRF8,MSL1,MYLK2,USP54,IL6ST,KCNA2,KCNJ3,KLC1,STXBP5,KTN1,SYTL4,MATN3,MBP,KCTD6,CD200,MSR1,RSPO2,MYO7A,HNRNPM,NAP1L1,NASP,NDUFA5,NEUROD1,NF1,NFE2L2,PCBP3,PAH,PAK3,CNTN3,ETFRF1,PCSK5,PDGFRA,SERPINI1,ST8SIA5,PLXNB1,MAGEL2,EPB41L4B,PPARA,RASGEF1B,PRKCB,GRAMD1C,DIRAS2,MASP1,CNTLN,TMEM260,ZSCAN32,PTPRG,CEP97,ENOX1,KHDRBS2,BSDC1,DPF2,RGS7,RGS12,SEC61A2,PBRM1,ZNF532,CARF,KIRREL1,PCMTD2,NEK11,ADAL,RPS6KA2,MEG3,FAM192A,SARS,SATB1,CSRNP3,LRRTM4,PRCD,ELMOD1,COPZ1,NLGN4Y,SH3BGR,SH3GL3,SHC4,BCAN,NUBPL,SLC6A1,SLC8A3,ELMO2,LIMCH1,SNRPN,DOP1A,ZSWIM8,SPTAN1,LARP4,ELOVL4,RGL1,DIP2A,KANK1,SULF2,STXBP1,SYN2,COBL,TAC3,PJA1,FAM208A,ADGRL3,SMG6,ZEB1,WDR7,FRYL,MTMR14,ZFP91,HEY2,PRRT1,CDK20,ZNF346,TRO,TRPM2,RUSC1,TTPA,CADM1,USP1,VLDLR,WRN,ZFP37,ZIC2,KCNT2,PLPP4,EML6,FTSJ1,SMARCAD1,CA10,PRDM2,DNALI1,RNF103,CIAPIN1,TRIM16L,PDSS2,DOCK8,NUP214,ZDHHC20,NETO1" MicroRNA hsa-miR-340:PITA hsa-miR-340:PITA_TOP PITA 1.15E-96 6.47E-93 6.69E-96 6.16E-95 194 626 "CLK4,ARID1A,CSMD3,SLC12A5,ZNF608,HECW2,PCDH19,OSBPL6,OSBPL8,LRRC7,ALCAM,TRMT9B,OGT,DPP10,LRCH2,LCORL,MAP4K3,CNTNAP1,GAS7,ALS2,API5,ASCL1,CAPRIN2,TMEM108,ATP2B3,ADGRB3,DCAF5,SYNJ1,JAZF1,SGCE,NIPA1,CABP7,CALM1,CAMK2A,SYT6,CAST,SPAG9,RUNX1T1,LDB2,KRIT1,MAGI1,CCPG1,ARHGEF6,AKAP5,CRY2,MICAL2,RIMS4,CNTNAP2,APPL1,PUM1,RIMS2,HDAC4,ZFYVE16,MAML1,SPOCK2,C8orf34,MAGI2,RHOBTB1,SACS,G3BP2,DMD,CALN1,DYNC1I1,NR1D2,CDON,CPEB2,DRD1,ABCC5,EDN1,SEMA3D,YAF2,TENM1,ELAVL2,ELAVL4,TMEM35A,ERBB4,MED12L,FGF13,UBE2E3,SLC37A3,NBEA,SMC2,ST6GALNAC3,STAU2,CHL1,NEK6,LUZP2,RFFL,CIT,TOX2,DHX35,IGF1,C5orf24,ZIC5,INSM1,ITGAV,JAK1,KCNA4,KCNK1,KIF5C,LIFR,PACRG,MAP2,MAT2A,CHIC1,LRP1B,MEIS2,KITLG,MITF,MXI1,NEXMIF,NFE2L2,OCRL,GPR137C,PBX1,PDGFRA,PIK3C2A,RETREG1,XRN1,PDZRN4,STRN3,LRP12,RETREG2,SH3KBP1,POU3F2,PPP3CA,PKN2,GRAMD1C,MTMR10,PTPRB,PTPRE,FAM120C,TMEM255A,FAM184A,FEZF2,RBBP6,REV3L,FIGN,RNF220,RIC8B,ZFHX4,SCN2A,FAM19A1,FNIP1,SUPT20H,SH3GL3,CPEB3,MAGI3,CHD9,SLC1A2,EPN2,SLC11A1,SLC12A2,RCOR3,PALLD,MYT1L,SOX11,SP4,TEX2,STAU1,NECAB1,C3orf70,SYT1,ANKRD28,CAMTA1,CAMSAP2,ADGRL3,FBXW11,TCF4,TRIM2,PUM2,AHCYL2,ZFPM2,TIAM1,HEY2,RIMBP2,KAT6B,TNS1,STXBP4,TRPC1,SSBP2,FAM155A,FLRT2,WIPF1,CADM2,PRDM8,RNF103,KCNAB1,PLSCR4,GOPC,KAT6A,PHTF2,FRMD6,SENP7" MicroRNA hsa-miR-130a:PITA hsa-miR-130a:PITA_TOP PITA 1.23E-96 6.88E-93 7.08E-96 6.52E-95 195 633 "ASIC1,ADCY2,CCDC85A,SLC12A5,GPR158,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,USP28,API5,MIER1,STK33,CAPRIN2,NCOA1,ATP2B1,ATP2B2,MTMR9,NOL4,ADGRB3,NRP2,LDLRAD4,THSD7A,CANX,MAP7,USP6,MAGI1,CFL2,SOCS6,KMT2C,PLAA,CLTC,QKI,CNR1,BTF3L4,ACBD5,CLOCK,CREB5,GDA,LRIG1,CHD5,SOCS5,APPL1,ARHGEF4,NRSN1,PPP6R2,ST18,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,ZEB2,CEP170,MAGI2,G3BP2,FAM107B,DLG2,DNM2,DPYSL2,ABCC5,ST8SIA3,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,EPB41L1,SLC43A2,ERBB4,ACSL4,SCML2,TESK2,MED12L,FOXF2,NBEA,NPTN,FUT9,GABRA3,GAP43,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KCNJ10,KIF5C,KIT,ARHGAP12,MBNL1,CHIC1,AFF1,MYT1,NAP1L3,NEUROD1,NPTX1,NUMA1,PDE1C,PDE4B,PDGFRA,PFKFB3,PIK3C2A,CCSER2,ST8SIA5,LRP12,FAT3,POU3F2,RELN,PSD,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,ATXN1,SCN3A,FAM19A1,PPP1R9A,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,MYT1L,SOX5,TEX2,CDK19,TSPYL2,SMOC1,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,FBXW11,TCF4,SATB2,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,RIMBP2,TNFRSF1B,R3HDM1,CSMD1,RBFOX2,TRPS1,TSC1,UBC,FAM155A,SLAIN1,TOM1L2,ZNF711,SPHK2,REEP1,WNK1,PMEPA1,MAP3K12,MFF,LRP8,SNX27,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-301a:PITA hsa-miR-301a:PITA_TOP PITA 1.23E-96 6.88E-93 7.08E-96 6.52E-95 195 633 "ASIC1,ADCY2,CCDC85A,SLC12A5,GPR158,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,USP28,API5,MIER1,STK33,CAPRIN2,NCOA1,ATP2B1,ATP2B2,MTMR9,NOL4,ADGRB3,NRP2,LDLRAD4,THSD7A,CANX,MAP7,USP6,MAGI1,CFL2,SOCS6,KMT2C,PLAA,CLTC,QKI,CNR1,BTF3L4,ACBD5,CLOCK,CREB5,GDA,LRIG1,CHD5,SOCS5,APPL1,ARHGEF4,NRSN1,PPP6R2,ST18,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,ZEB2,CEP170,MAGI2,G3BP2,FAM107B,DLG2,DNM2,DPYSL2,ABCC5,ST8SIA3,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,EPB41L1,SLC43A2,ERBB4,ACSL4,SCML2,TESK2,MED12L,FOXF2,NBEA,NPTN,FUT9,GABRA3,GAP43,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KCNJ10,KIF5C,KIT,ARHGAP12,MBNL1,CHIC1,AFF1,MYT1,NAP1L3,NEUROD1,NPTX1,NUMA1,PDE1C,PDE4B,PDGFRA,PFKFB3,PIK3C2A,CCSER2,ST8SIA5,LRP12,FAT3,POU3F2,RELN,PSD,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,ATXN1,SCN3A,FAM19A1,PPP1R9A,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,MYT1L,SOX5,TEX2,CDK19,TSPYL2,SMOC1,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,FBXW11,TCF4,SATB2,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,RIMBP2,TNFRSF1B,R3HDM1,CSMD1,RBFOX2,TRPS1,TSC1,UBC,FAM155A,SLAIN1,TOM1L2,ZNF711,SPHK2,REEP1,WNK1,PMEPA1,MAP3K12,MFF,LRP8,SNX27,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-130b:PITA hsa-miR-130b:PITA_TOP PITA 1.23E-96 6.88E-93 7.08E-96 6.52E-95 195 633 "ASIC1,ADCY2,CCDC85A,SLC12A5,GPR158,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,USP28,API5,MIER1,STK33,CAPRIN2,NCOA1,ATP2B1,ATP2B2,MTMR9,NOL4,ADGRB3,NRP2,LDLRAD4,THSD7A,CANX,MAP7,USP6,MAGI1,CFL2,SOCS6,KMT2C,PLAA,CLTC,QKI,CNR1,BTF3L4,ACBD5,CLOCK,CREB5,GDA,LRIG1,CHD5,SOCS5,APPL1,ARHGEF4,NRSN1,PPP6R2,ST18,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,ZEB2,CEP170,MAGI2,G3BP2,FAM107B,DLG2,DNM2,DPYSL2,ABCC5,ST8SIA3,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,EPB41L1,SLC43A2,ERBB4,ACSL4,SCML2,TESK2,MED12L,FOXF2,NBEA,NPTN,FUT9,GABRA3,GAP43,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KCNJ10,KIF5C,KIT,ARHGAP12,MBNL1,CHIC1,AFF1,MYT1,NAP1L3,NEUROD1,NPTX1,NUMA1,PDE1C,PDE4B,PDGFRA,PFKFB3,PIK3C2A,CCSER2,ST8SIA5,LRP12,FAT3,POU3F2,RELN,PSD,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,ATXN1,SCN3A,FAM19A1,PPP1R9A,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,MYT1L,SOX5,TEX2,CDK19,TSPYL2,SMOC1,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,FBXW11,TCF4,SATB2,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,RIMBP2,TNFRSF1B,R3HDM1,CSMD1,RBFOX2,TRPS1,TSC1,UBC,FAM155A,SLAIN1,TOM1L2,ZNF711,SPHK2,REEP1,WNK1,PMEPA1,MAP3K12,MFF,LRP8,SNX27,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-454:PITA hsa-miR-454:PITA_TOP PITA 1.23E-96 6.88E-93 7.08E-96 6.52E-95 195 633 "ASIC1,ADCY2,CCDC85A,SLC12A5,GPR158,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,USP28,API5,MIER1,STK33,CAPRIN2,NCOA1,ATP2B1,ATP2B2,MTMR9,NOL4,ADGRB3,NRP2,LDLRAD4,THSD7A,CANX,MAP7,USP6,MAGI1,CFL2,SOCS6,KMT2C,PLAA,CLTC,QKI,CNR1,BTF3L4,ACBD5,CLOCK,CREB5,GDA,LRIG1,CHD5,SOCS5,APPL1,ARHGEF4,NRSN1,PPP6R2,ST18,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,ZEB2,CEP170,MAGI2,G3BP2,FAM107B,DLG2,DNM2,DPYSL2,ABCC5,ST8SIA3,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,EPB41L1,SLC43A2,ERBB4,ACSL4,SCML2,TESK2,MED12L,FOXF2,NBEA,NPTN,FUT9,GABRA3,GAP43,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KCNJ10,KIF5C,KIT,ARHGAP12,MBNL1,CHIC1,AFF1,MYT1,NAP1L3,NEUROD1,NPTX1,NUMA1,PDE1C,PDE4B,PDGFRA,PFKFB3,PIK3C2A,CCSER2,ST8SIA5,LRP12,FAT3,POU3F2,RELN,PSD,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,ATXN1,SCN3A,FAM19A1,PPP1R9A,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,MYT1L,SOX5,TEX2,CDK19,TSPYL2,SMOC1,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,FBXW11,TCF4,SATB2,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,RIMBP2,TNFRSF1B,R3HDM1,CSMD1,RBFOX2,TRPS1,TSC1,UBC,FAM155A,SLAIN1,TOM1L2,ZNF711,SPHK2,REEP1,WNK1,PMEPA1,MAP3K12,MFF,LRP8,SNX27,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-301b:PITA hsa-miR-301b:PITA_TOP PITA 1.23E-96 6.88E-93 7.08E-96 6.52E-95 195 633 "ASIC1,ADCY2,CCDC85A,SLC12A5,GPR158,HECW2,OSBPL1A,SRPX,PITPNM2,LRCH2,USP28,API5,MIER1,STK33,CAPRIN2,NCOA1,ATP2B1,ATP2B2,MTMR9,NOL4,ADGRB3,NRP2,LDLRAD4,THSD7A,CANX,MAP7,USP6,MAGI1,CFL2,SOCS6,KMT2C,PLAA,CLTC,QKI,CNR1,BTF3L4,ACBD5,CLOCK,CREB5,GDA,LRIG1,CHD5,SOCS5,APPL1,ARHGEF4,NRSN1,PPP6R2,ST18,SNPH,ARHGAP24,DCAF8,LONRF1,MAML1,ZEB2,CEP170,MAGI2,G3BP2,FAM107B,DLG2,DNM2,DPYSL2,ABCC5,ST8SIA3,EDN1,FRY,KMT5B,EGR3,PAN3,EMX2,EPB41L1,SLC43A2,ERBB4,ACSL4,SCML2,TESK2,MED12L,FOXF2,NBEA,NPTN,FUT9,GABRA3,GAP43,ARFIP1,PPARGC1A,RAB30,TNRC6A,KDM2B,RAPGEF4,GRB10,GRM7,CIT,SOX21,BACH2,MIER3,HLF,AGFG1,IGF1,ZIC5,KCNJ10,KIF5C,KIT,ARHGAP12,MBNL1,CHIC1,AFF1,MYT1,NAP1L3,NEUROD1,NPTX1,NUMA1,PDE1C,PDE4B,PDGFRA,PFKFB3,PIK3C2A,CCSER2,ST8SIA5,LRP12,FAT3,POU3F2,RELN,PSD,MTMR10,PTPRD,PTPRG,RAB5B,ATG16L1,RBBP8,KLHDC8A,ROBO1,ROBO2,CLIP1,RTN1,ATXN1,SCN3A,FAM19A1,PPP1R9A,KIF16B,CPEB3,CHD9,BTBD3,WDR47,CCDC88A,CPEB4,SNAP25,MYT1L,SOX5,TEX2,CDK19,TSPYL2,SMOC1,NKAIN2,ERBIN,PLCB1,SYN2,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,FBXW11,TCF4,SATB2,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,RIMBP2,TNFRSF1B,R3HDM1,CSMD1,RBFOX2,TRPS1,TSC1,UBC,FAM155A,SLAIN1,TOM1L2,ZNF711,SPHK2,REEP1,WNK1,PMEPA1,MAP3K12,MFF,LRP8,SNX27,WNK3,PDSS2,RGS7BP,FXR1,FRMD6" MicroRNA hsa-miR-643:mirSVR_highEffct hsa-miR-643:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-96 7.26E-93 7.46E-96 6.87E-95 251 1056 "NCKAP5,GPR158,HECW2,RTL9,OSBPL1A,OSBPL8,SPARCL1,BCAR3,FAM135A,ALK,ANK3,LCORL,ARNTL,RNF182,B3GALT2,DPY19L3,TTLL9,BACH1,CFLAR,DST,IL33,MMD2,CA8,CACNA1B,CACNA1E,DDR1,KALRN,CAST,SPAG9,CD86,ZBED1,CDH2,KCNAB3,LGI1,CLGN,NUMBL,RAB33A,CLCN3,QKI,NIPBL,CNR1,SLC4A8,ACBD5,TOGARAM2,CNRIP1,CLOCK,RBM39,GDA,CSF2RA,ARHGEF10,ATRNL1,PHACTR3,DZIP3,PHF14,CTNND1,ST18,GAPVD1,TCAF1,TOX,ZFYVE16,LONRF1,DGKB,ZNF804A,ZEB2,CNIH3,DDX46,SV2B,USP3,CPEB2,ABI1,DTNB,ECM2,E2F5,FAM135B,HIPK3,RASGRP1,KLHL5,YAF2,PHF20L1,MBNL2,IRAK4,KCNMB2,CDKL3,F5,WAC,ZIC4,SEC24B,SLC9B2,GTF2IRD2,SUCO,FOXG1,C2orf88,WDR83,STAU2,NRG3,STAG2,GABRA1,GABRA2,ZMYND11,C15orf41,DISC1,LRRC37A6P,MSTN,FREM1,MALT1,DBF4,SPIN1,RAB30,GLRB,ZNF638,KIAA1958,GNAS,GRID1,GRM8,FAM19A2,ZBTB49,PSIP1,GUCY1A2,MAEL,HMGB1,HNRNPK,NEGR1,SMAP1,C5orf24,RBPJ,IL6ST,DIPK1A,SLC35G1,KCND2,KCNJ16,KIT,LAMA2,INSYN2,PAXBP1,HECTD2,SYT9,MEIS1,KCTD6,MOG,ADAM22,ZNF92,MTR,MYO9A,NEUROD1,NUCB2,IGSF11,CHAMP1,OLR1,CLDN11,PCSK5,PDE1A,PDE4D,NALCN,PLP1,PRIMPOL,LRP12,SCHIP1,PRRX1,SDK2,ING3,PPM1B,PRKCZ,DIRAS2,GDPD1,RELN,BCAS3,SIDT1,PTHLH,PTPRB,OCIAD1,ACSS3,VEPH1,GTDC1,RFX4,PBRM1,CCDC82,ZNF532,CARF,RORB,CCDC102B,RPE,UEVLD,ATP8B4,ACER3,TCP11L1,CNTNAP3,LGR4,ATAT1,RYR3,CCDC112,FAM19A1,LINC00461,FNIP1,NTNG1,PPP4R3A,WDR47,RUFY2,CCDC88A,SLC15A2,TET1,SMARCC2,SMARCE1,RIMS1,MBD5,CABCOCO1,ZNF415,TRERF1,ZC3H13,RBM26,SST,LARP4,NEK4,RGL1,SYNE2,PLCB1,SYPL1,FAM208A,ANO4,ATMIN,EHBP1,SATB2,ZEB1,TCF12,DOCK9,PCDHB9,FRYL,AHCYL2,FAM200B,AP4E1,ZNF106,SLC44A1,ASXL3,ZFP91,TMPO,CSMD1,KAT6B,TPD52L2,WIPF1,RICTOR,PCDH20,ZNF24,ANKS1B,SYNC,SLC38A1,FIP1L1,TMEM163,FAM13C,CASC15,MSRB3,NETO1,SLC4A10" MicroRNA hsa-miR-759:mirSVR_highEffct hsa-miR-759:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-96 8.43E-93 8.65E-96 7.97E-95 230 889 "SDE2,ASIC2,CLK4,NCKAP5,CSMD3,NDRG3,SLITRK1,SORCS1,PLEKHH1,ADRA1D,OSBPL1A,ALCAM,UNC79,APC,BCAS1,MIER1,IGDCC4,CADPS,LINC00173,STK33,CAPRIN2,ZBTB10,ATP2B1,MTMR9,DPY19L3,MYOM1,ADGRB2,CFLAR,FUBP1,CA12,CACNA1B,KALRN,BRSK2,INA,SCARB1,C1orf52,LRRFIP1,CDO1,CCPG1,SRSF11,JAM2,IGFBP7-AS1,PLAA,CLTC,FBXO7,FAM149A,AKAP6,SUMF2,PNKD,SEC31B,VCAN,CYBB,RIPOR2,DCAF8,MATR3,BRINP1,CEP170,GSDME,USP3,DNM2,SLC25A18,ATL1,FRY,PHF20L1,RASA4,PAN3,RABEPK,MRPL10,RTN3,TOMM40L,IQCG,PSD2,SYT3,NELFCD,TACC2,FAM49B,NSG1,PNMA2,ZNF512,GABRA1,RAPGEF6,GAP43,ZNF559,DISC1,TUBA8,PCDH17,GGT7,MALT1,LYVE1,COPS8,PCDH11X,GNAS,GPD2,GPM6A,GPM6B,PCLO,GRIK1,KIF3A,SOX21,ZHX1,HMGB1,ZDHHC15,HTR5A,DISP2,INPP5B,SLC6A17,KCNH2,IPO5,CYP27C1,NCOA7,NAT8L,MBNL1,SRSF12,MMP16,MOG,CD200,STK32C,MTR,MYBPC1,MYT1,NAP1L1,ZC3H12B,NELL2,CNOT4,NTRK2,NTRK3,OGDH,GPR137C,GLIPR1L2,HERC2P3,NOMO2,ZNF426,PURG,MAPKAP1,ING3,SPATA6,NXPH1,PPM1B,PPP2R5C,MASP1,VPS13C,QRICH1,PLPPR1,BDNF-AS,PXK,PTPRE,PTPRG,FAM184A,RFX3,RGS12,RNASEL,RPRD1A,KLHDC8A,CCDC25,ACER3,LGR4,S100B,ATXN7,ELMOD1,CASC3,HSPA4L,SGK1,SH3BGR,ITSN1,KIF16B,CHD9,FBXO11,FNDC3A,NLGN1,DHX30,RUFY2,SLC11A1,EFHD1,SLIT1,SNRPN,MYO16,PDZD2,KDM3A,SP4,ZC3H13,ATP10B,CLASP2,NXT2,C3orf70,SYN1,ASTN2,KAZN,ADGRL3,SATB2,TRIM2,SYNE1,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,TPM1,TRO,TSC1,SGK3,SLC35A4,SLAIN1,BCL2L13,CCDC14,P2RY12,ZNF781,CLDND1,PCDH20,MICU3,MKRN3,TMEM198,ZNF184,SYNC,DHX33,PRDM2,CIAPIN1,MDH1B,PCDH15,KCNAB1,PCBP4,WNK3,PDSS2,KAT6A,KLHDC1,CPNE4,JPH3" MicroRNA hsa-miR-630:mirSVR_highEffct hsa-miR-630:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-96 8.98E-93 9.21E-96 8.48E-95 270 1217 "CPNE2,CDC7,GRAMD1B,ADRB2,SPOP,ABCD2,LRCH2,ANK3,LCORL,MAP4K3,APBA2,UPRT,MIER1,TMEFF1,CADPS,ATP1A1,NOL4,DPY19L3,DOCK11,SCAPER,WASF1,KALRN,CANX,SLC25A14,ISPD,ZNF501,MTMR7,INA,CD86,CDH2,LRRFIP1,LGI1,CFL2,NDST3,CLTC,TJP2,TMEM184B,COL4A5,ACBD5,ANKRD44,GDA,CS,RGS6,DZIP3,PPP6R2,USP6NL,KATNAL2,TCAF1,ARHGAP24,ZFYVE16,LIN54,TMEM170A,PABPC5,ARMCX2,DNAJC6,KLHL3,RHOBTB1,SV2B,NTM,SGSM2,CDON,RASGRP1,FRY,FSD1L,PHF20L1,KCTD3,ELAVL2,PLEKHA1,DCTN4,LRRC17,CDHR1,F3,F8,CLVS1,ZNF585B,SH3YL1,DLC1,ST3GAL6,SLC9B2,FER,FGF12,FGF14,FOXG1,FLT1,EFCAB2,JKAMP,PDLIM5,AP4B1,STAG2,GABRA1,HRASLS5,GABRG2,BRPF3,SALL3,ZNF559,DISC1,GART,CRCP,COPS8,SPIN1,GLI2,GLS,MSL3,GNAS,ZNF782,LNX1,EML4,PCLO,GRIA2,PSIP1,GUCY1B1,MAP4K5,WIF1,RASSF8,FRMD3,MIER3,HMGCR,HNMT,ZDHHC15,CFAP126,LRRC75A,RAB41,LRRCC1,USP54,KCND2,KIF2A,PAXBP1,HECTD2,NCOA7,LSAMP,MAOB,MAP4,MATN2,MEIS2,KCTD6,POC1B,CD200,ADAM22,MSR1,NAP1L2,NDUFA5,NF1,CNOT4,NTRK2,OPA1,LOC100128398,PCDH9,GPR85,GNG2,PIK3C2A,FAM218A,GPSM2,HMGCLL1,PURG,LRP12,MINDY2,CEP41,PRKCZ,SLC26A11,GRAMD1C,HYDIN,KLK6,MDGA2,ANKHD1,TMEM260,PTPRH,PTPRN2,PTPRZ1,MARCH1,PID1,CEP97,ZNF793,NWD1,OXR1,RASGRF1,KHDRBS2,RFX4,RIC8B,SETD5,RORB,ELP2,CCDC102B,ATP8B4,TCP11L1,LRRK2,ABCA11P,ZNF568,ZNF331,TMEM156,FAM192A,SALL1,ATXN2,FNIP1,SUPT20H,SH3BGR,ITSN1,NTNG1,HKDC1,CHD9,SLITRK3,SLC1A3,BTBD3,WDR47,SEPHS1,SPHKAP,SLIT1,CPEB4,ZFP1,LIMCH1,SNRPN,KIF21B,BDP1,MYCBP2,ZC3H13,LMO3,DIP2A,FGD4,ZFR2,VPS13A,PLCB1,CAMTA1,EXOC7,FAM208A,UNC5D,ADGRL3,EHBP1,WASHC4,PUM2,USP32P1,GPRIN3,FRYL,ITGB3BP,AP4E1,ZMAT3,TGFBR3,HEY1,ACTR6,TLR4,TMPO,RBFOX2,TPM1,TPM4,RGMB,METTL3,ANKRD20A2,CLHC1,SGK3,FLRT2,ZNF781,RICTOR,ZNF711,ZNF708,ZNF17,KCNT2,LYPD6,ZNF154,LAMP5,WNK1,RNF103,ADAMTS9,PCDH15,PDSS2,FAM13C,DOCK8,PAK5,PHTF2,FBXO36,CASC15,TRAM2-AS1,RNF170" MicroRNA hsa-miR-520a-5p:mirSVR_highEffct hsa-miR-520a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.21E-96 1.24E-92 1.27E-95 1.17E-94 249 1042 "ASIC2,BRAP,FZD9,CC2D2A,NT5C3B,SHTN1,CDK13,CAPRIN2,ASPH,NUMB,RASL11B,SLC4A4,ZNF582,N4BP2L1,TTLL9,ADGRB3,KSR1,MMD2,CACNB2,ZNF555,KALRN,SCARB1,SEPT7,CDC42,CFL2,CHN2,JAM2,IGFBP7-AS1,CLTB,QKI,SULT4A1,COL9A1,BTF3L4,ABI3BP,CHD1L,FAM171B,RNF14,ANKRD44,CSNK1G3,ATRNL1,PLXNA4,ERC2,ARHGEF4,NRSN1,DOCK4,RIPOR2,DCAF8,TOX,DAPK1,SIRPA,ARMCX4,KIAA0753,GSDME,DDX46,SNAP91,TMCC2,DPP6,DRP2,ECM2,ABCC5,SNX29,RASGRP1,EGFR,KMT5B,ELN,TUBD1,EPB41L1,EPB41L2,TLR7,TUBB4A,ST3GAL6,FCGR3A,FER,PCYOX1,SLC37A3,ATP6V1H,ZNF605,CELF1,ZNF512,GABRA1,ILDR2,BRPF3,GALC,IQGAP2,INPP5K,TUBGCP4,SESN1,GFRA2,HEPN1,PCDH11X,INSM2,GPM6B,GRIA2,GRIA4,PLCD4,GRM7,GRM8,COQ10A,IRAK3,VSIG4,HMGCL,AGBL5,OPALIN,SHISA6,IDH3B,IGF1,USP54,ITPKB,KCNB1,KCNJ3,KCNK2,CREG2,KIF2A,IPO5,PAXBP1,SMAD1,MEIS1,MEIS2,MID1,POC1B,MN1,MOBP,STK32C,MTTP,RSPO2,NDP,NODAL,NOVA1,HCN1,NUCB2,ODF2,OLR1,PBX1,PDE3B,PFKFB2,HERC2P3,RETREG1,XRN1,GPSM2,PLP1,HMGCLL1,ZNF426,MTRF1L,PLXNB3,MAPKAP1,TNPO2,NXPH1,TATDN3,PPP2R5E,RANBP3L,PRKCB,RAB39A,PKN2,SLC26A11,GRAMD1C,DIRAS2,MDGA2,ANKHD1,MTMR10,TMEM260,PTPRB,OCIAD1,ZSCAN2,MARCH1,TMEM255A,RALGDS,SUSD4,ENOX1,ZYG11B,PRRT2,FIGN,UBR7,RGS4,RIC8B,RNASEL,TMLHE,ARMC5,CARF,NEK11,ARMH4,ACER3,RTN1,SEMA6D,ATXN2,ATXN7,FAM19A1,ELMOD1,SOX6,ASRGL1,SGK1,SH3GL3,FBXO11,PAAF1,PPP4R3A,SLC22A4,RCOR3,DOP1A,SON,KDM3A,UHRF1BP1L,KDM4C,KIF1B,RBM26,EPB41L3,NKAIN2,MAPK8IP3,ZSCAN29,CEP68,DIP2A,ACSBG1,SYNE2,CAMTA1,FAM208A,FBXW11,KLHL4,ATMIN,EHBP1,SATB2,RPGRIP1L,WASHC4,WDR7,SYNE1,NAT16,PUM2,CRB1,AP4E1,TMPO,ZNF384,ZNF346,TRO,SLAIN1,CCDC14,ZNF24,ZNF32,FMN2,TCEAL7,CADM2,SCG2,VPS35L,PCDH15,PPP1R3F,TMEM163,PLSCR4,PDSS2,UBE3B,PAK5,FBXO36,NHSL1,ZDHHC20" MicroRNA hsa-miR-17*:mirSVR_highEffct hsa-miR-17*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-96 1.73E-92 1.77E-95 1.63E-94 246 1019 "SERPINA3,ACLY,CSMD3,FMNL2,SLITRK1,CCDC85A,PTCHD1,OSBPL1A,NR0B1,ADGRF5,AMPD2,LRCH2,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,ALS2,BCAS1,API5,CDC14B,ASTN1,DDX3Y,DYNLL1,ADAM23,OSGIN2,CACNA1D,CACNB2,KALRN,CAMK2D,TRIM41,SPAG9,NFS1,ZNF501,METTL6,CCNH,INA,CD38,LRBA,CDC27,LRRFIP1,CDO1,NPIPA1,RCBTB2,SRSF11,KMT2C,MAP4K4,AKAP7,AKAP6,COL4A5,LETMD1,ABI3BP,AKAP12,TRIM69,FEZ2,CSNK1G3,SIPA1L1,CST3,APPL1,PHF14,GAPVD1,RIPOR2,ARHGAP24,TOX,KIAA0513,KIAA0586,IST1,DAPK1,PABPC5,BLOC1S6,G3BP2,EXOG,CPEB2,DPYSL2,EBF1,WDPCP,TSPAN5,EDNRA,PHC2,HIPK3,RASGRP1,FRY,YAF2,GOLGA7,TENM1,ELAVL2,EML1,VPS13B,CEP78,ZSCAN30,MED12L,FGF11,BAIAP2,MAD2L2,CAMSAP1,POLK,MEX3B,UFM1,ATP2C1,GABRA2,JPH4,ARPP21,SALL3,ERAP1,KIAA1841,DNER,NEU3,MSTN,TOX3,MSL3,ZNF638,CBX1,GNAS,ADGRA3,GPD2,DIDO1,PLCD4,GRM1,GRM3,KAT7,HPS5,ZHX1,KLF12,LINC01102,SMAP1,NKD1,IL6R,IL6ST,ZNF678,SLC35G1,KCNC1,KCNMA1,KIF5C,SYTL4,FGFBP3,MBNL1,MDM4,MEIS1,MTTP,RSPO2,NACA,NAP1L1,CNOT4,NRCAM,NRDC,OPA1,GLIPR1L2,ENPP2,RC3H2,LRP12,LRRN3,PPP3CA,RAB39A,GRAMD1C,RELN,KLK6,CNNM2,SAMD9,CNTLN,PTHLH,SPDL1,PTN,PTPRO,PTPRZ1,PPP2R3C,FAM184A,RAP1GDS1,ZNF493,OXR1,RADX,REV3L,GTDC1,TTLL7,ZFHX4,CARF,RPE65,UEVLD,CNTNAP3,RYR3,FAM192A,DGLUCY,ATXN7,FAM19A1,SLC30A10,ZFP2,SOX6,CASC3,SCAF8,NLGN4Y,ITSN1,CPEB3,NLGN1,PPP4R3A,RUFY2,SLC6A8,TET1,MAPKBP1,MYO16,UNC80,USP33,KDM4C,ZNF423,TAB2,CLASP2,POGZ,SSPO,STAU1,RGL1,NSFL1C,KLHL7,FGD4,PRRC2C,PJA1,VWA3A,ZFP90,ZEB1,TRIM2,TCF12,WASHC4,AKNA,SIRT1,ITGB3BP,AP4E1,AKTIP,ERCC6L2,TRIO,TRPS1,TMEFF2,UBE3A,PLEKHH2,MEAF6,RICTOR,SLC47A2,SF1,ZIC3,ZNF19,ZNF28,ZNF74,POLR3H,FSTL5,ANKS1B,SYNC,WNK3,FZD3,CASC15,KLHDC1,SLC4A10,GAN" MicroRNA hsa-miR-27a*:mirSVR_lowEffct hsa-miR-27a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.06E-96 2.84E-92 2.90E-95 2.67E-94 254 1087 "ABAT,KDM5D,CSMD2,ADCY2,ADD1,ADD3,PWWP2A,RNF150,KCTD16,OSBPL1A,KIAA1324,DISP3,CC2D2A,BBOX1,SYT13,PITPNM2,ANK3,PPFIA4,PKP4,EPB41L5,GPAM,ALS2,FAM131A,TNRC6C,AQP6,MARCH3,BRINP2,NCOA1,DDX3Y,DPY19L3,RIPK1,ADAM23,ADGRB2,BCL2L2,SCAPER,MAP7,CBS,USP2,CD86,NEURL1,C1orf52,CDO1,FOXN3,ASIC3,CHM,CASC2,NDST3,RAB28,PPT2,CNTN1,COL9A3,ZNF521,HS3ST5,SLC35F1,RNF14,ANKRD44,TRIM69,AATK,RGS6,ARHGEF10,CSNK1G3,PDE4DIP,RIMS2,ARHGAP32,KATNAL2,RIPOR2,RASSF2,ZBTB24,RUSC2,TMEM130,HS3ST2,E2F5,WDPCP,RASGRP1,PHF20L1,MRO,EIF4G1,PLEKHA1,ELN,PAN3,EIF1,HSD17B14,MRPL37,FAM198B,FABP7,TMEM132C,CHST15,FECH,FGF13,UBE2E3,FLT1,PSD2,KHDRBS3,NSG2,CELF1,CGREF1,ST6GALNAC3,ZMAT1,DENND2A,GAD2,BRPF3,SALL3,IQGAP2,SESN1,ADAM28,GFER,MALT1,BRD8,CRCP,TOX3,STARD3,LNX1,STON1,STMN2,ADAMTS13,GRM1,NEGR1,OPALIN,HSD17B1,HTR2A,LIX1,ZNF385B,KCNJ3,KCNJ9,KCNMA1,KCNN2,CREG2,ASPRV1,PIK3AP1,MBD1,SYT9,MEIS2,MT3,ZNF92,RSPO2,P2RY13,NBL1,NCF2,NEFM,NF1,NFYA,PCBP3,OPHN1,PAH,PAK3,ENPP2,GNG2,PFKFB4,SERPINI1,NALCN,SNX10,PLCL1,MTRF1L,RC3H2,SDK2,TATDN3,PPP3CB,VSTM2L,CEP41,GDPD1,RELN,WBP1L,GON4L,MDGA2,BDNF-AS,PTHLH,CASTOR1,PYGM,ZSCAN2,TUG1,MARCH1,RALGDS,OXR1,FIGN,RGS12,ROBO1,NEK11,GLDN,MEG3,RTKN,HOGA1,ELMOD1,TRIM46,SFPQ,COPZ1,ARX,FHOD3,SEC31A,WDR37,NBPF1,SLC6A1,LRRC55,SEPHS1,SLC12A4,KIF13A,CABCOCO1,ZNF415,SNRPN,KDM4B,USP33,WDTC1,KDM4C,IQSEC2,ZNF621,RGL1,PHLDB1,KANK1,SULF2,VAMP1,SYP,ROBO3,TAL1,UNC5D,ATMIN,ZEB1,TPCN2,SZT2,USP32P1,FRYL,DICER1-AS1,SPX,MTMR14,TIE1,TK2,SYNPO2,PRMT8,TRH,TRPC3,ZMYND8,RFTN2,PLEKHH2,MEAF6,BEST1,LAT2,GUSBP1,XRCC4,LGI4,TRIM9,EML6,ZNF189,SPIRE1,FTSJ1,ZNF213,CA10,RGMA,PRDM8,RNF103,GAL3ST3,NAV3,PCBP4,WIPF2,RTN4,CASC15,NETO2" MicroRNA hsa-miR-513c:mirSVR_highEffct hsa-miR-513c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.61E-96 3.71E-92 3.79E-95 3.49E-94 261 1147 "CPNE2,SDE2,ACADM,NBAT1,SLITRK1,DPY19L2P4,INTS2,GPR158,HECW2,ALCAM,SRPX,OGT,LCORL,LGR5,PPP4R4,TMEM263,MARCH3,ASPH,NUMB,ATM,EIF4G3,ATP1B3,N4BP2L1,LINC00847,DCAF5,CALM1,KALRN,TRIM41,CANX,VXN,ZNF501,LRBA,SEPT7,CDH18,CCPG1,GPR37L1,CHGA,KMT2C,QKI,MAP4K4,ARMC8,BTF3L4,FAM171B,PREPL,RBM39,RNF14,MROH8,FEZ2,CSNK1G3,SOCS5,NOS1AP,FGFR1OP2,KIAA0586,DGKB,TMEM170A,GIT2,DCC,HP1BP3,NTM,FAM107B,DLG2,DYNC1I1,DPH1,RCAN1,EDNRA,SGK2,FCF1,FRY,PHF20L1,SUGP2,ELAVL3,DCTN4,LRRC17,STX2,SIRPB1,EXTL2,ADGRV1,F3,F5,FAM198B,WAC,GORAB,FGF1,POLR1B,FOXG1,SYNCRIP,NBEA,SMC2,ST6GALNAC3,MSANTD4,NRG3,OGA,STAG2,MEGF11,CAB39,GAD1,ZMYND11,MYOZ2,GATM,NEU3,MSTN,ADAM28,PCDH17,GHR,LYVE1,GPR75,GLS,CBX1,INSM2,DCLK2,GPD2,GPM6B,TMEM121B,DIDO1,GRIA4,SERP2,GRM5,BTN2A1,PSIP1,RNFT2,TOX2,ARHGAP36,AGBL5,HSF2,IDH3A,DOCK7,ITGAV,KCNC2,KCNK1,NCOA7,MBNL1,TM6SF1,MDM4,MITF,AFDN,MMP16,ZNF680,SAMD5,ZNF92,MYO9A,NEFM,NEFH,NF1,VWA2,CNOT4,NOVA1,PAK3,PDE3B,GNG2,OLA1,NALCN,CCSER2,SNX10,PMS2,SLC36A4,MINDY2,PPM1B,PPP2R5C,RASGEF1B,MAPK10,MASP1,SYTL2,CNTLN,PTX3,ZSCAN2,PID1,OXR1,ZDHHC14,SLC6A15,ZYG11B,RET,ERI2,RFX3,RIT2,SEC61A2,ZFHX4,CARF,GSTCD,CCDC25,RPL15,UEVLD,ATAT1,KCNIP1,FNDC3A,SLITRK3,PEX26,PPP4R3A,RUFY2,SLC6A8,CCDC88A,NAPB,SMARCE1,SNCA,ZNF415,BDP1,KDM4C,RBM26,TAB2,ATP10B,PBLD,TROVE2,CLSTN2,NECAB1,VAMP1,DNAJC9,SYPL1,PJA1,DDHD2,ADGRL3,AGTPBP1,KLHL4,TCF7,WDR7,DOCK9,GPRIN3,PMS2CL,ITGB3BP,LEFTY2,AP4E1,AKTIP,ARL10,TIAM1,HEY2,RBFOX2,SEZ6L,TPM1,NPL,ZNF384,SYNPO2,RUNDC3B,AMACR,TSN,SGK3,CADM1,RPL7L1,UBE2H,UBE3A,PLEKHH2,RICTOR,SLC13A3,ZNF711,ZNF708,ZNF17,MICU3,PLPP4,FSTL5,ANKS1B,PRDM10,RNF103,HPS4,CIAPIN1,KCNAB1,MVB12B,RGS7BP,AMN1,DOCK8,PHTF2,JMJD1C,TIGD6,FXR1,NETO1" MicroRNA hsa-miR-4275:mirSVR_highEffct hsa-miR-4275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.73E-96 3.78E-92 3.86E-95 3.56E-94 238 958 "CLK4,ACTN2,CSMD3,ADAR,KLHL32,ADD2,BRAP,PWWP2A,KLHL13,OSBPL8,CC2D2A,SPARCL1,SMIM17,PCDH10,OGT,LRCH2,LCORL,PHF12,PPFIA1,EPB41L5,UPRT,ALS2,MIER1,CASK,ARHGAP5,LINC00173,DDX3Y,ATM,ATP2B1,BCL2L2,BMPR1B,NAE1,CACNA1G,THSD7A,SLC25A14,CBR1,ZNF501,C1orf52,LRBA,CDC42,LRRFIP1,SLC25A27,COL11A2,ZFP28,PREPL,ARHGEF10,CSNK1E,PHF14,CCDC144A,TOX,ZFYVE16,MATR3,BRINP1,ARMCX4,ZEB2,MYEF2,MAGI2,BLOC1S6,SMG7,SPOCK3,NTM,WDR20,CCDC3,NR1D2,GNE,GOLT1B,E2F6,AASDH,FAM13A,PHF20L1,APH1A,MBNL2,KCTD3,EIF4G2,TMEM35A,EIF1,VPS13B,COQ7,STX2,RAB9B,DENND4A,TLR7,KATNAL1,WAC,TMEM132C,DLC1,CEP78,TESK2,KIAA1109,FGF1,CAP2,NELFCD,SMC2,CELF1,STAG2,GABRA2,CHL1,GABRG2,CAB39,ZMYND11,IQGAP2,MTHFD2,MYOZ2,GATM,PPARGC1A,LYVE1,HPGDS,DBF4,ZNF638,GNAS,ADGRA3,GPD2,RAPGEF4,GRIA4,GRM1,SOX21,PSIP1,ARHGAP19,HMGB1,SMAP1,IGFBP1,RBPJ,TJAP1,IGSF1,INSM1,ITGAV,SLC35G1,OLFM3,KCNA4,KTN1,MAP2,MBD1,AFDN,MOG,JAKMIP3,MSR1,RSPO2,PABPC1L2A,NAP1L1,NAP1L2,NAP1L3,NDUFA5,NF1,OCRL,GPR137C,PRTG,PDE1C,PDE3B,PDE4D,SLC10A4,NALCN,CCSER2,FAM216A,PLIN1,PRIMPOL,PDZRN4,SCHIP1,SPATA6,SEPT4,EPB41L4B,POLR2F,MINDY2,TATDN3,PPP3CB,MASP1,NDUFS7,VPS13C,ANKHD1,STK32A,OCIAD1,PTPRZ1,ZNF615,ENOX1,SLC6A15,RET,RFX3,NUDT11,ZNF532,DCUN1D2,RAVER2,ROBO2,ACER3,SCN2A,LRRTM4,PEAR1,SUPT20H,ARX,MAGI3,SYBU,SLC1A7,NAPB,RCOR3,CMTR2,DOK5,MYCBP2,ERC1,ZNF423,ZC3H13,POGZ,LARP4,NKAIN2,SEPT3,ZC3H4,VPS13A,SYT4,PJA1,DDHD2,CAMTA1,TAF6,TBCEL,CLASP1,SZT2,DOCK9,PUM2,FRYL,SIK3,FAM200B,SLC44A1,HEY1,BHLHB9,TMPO,CSMD1,NPL,RGMB,RUNDC3B,TSC1,ZIC2,MICU3,FTSJ1,EMSY,CSDE1,PCDH15,C12orf4,PDSS2,CERS6,JMJD1C,TRAM2-AS1,IFT88" MicroRNA hsa-miR-153:mirSVR_highEffct hsa-miR-153:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.57E-96 4.81E-92 4.91E-95 4.52E-94 230 896 "VWA5B2,RALGAPA1,KCNH8,NCKAP5,CCDC85A,GALNT13,KIAA1211,RNF150,SLC24A4,HECW2,HACE1,OSBPL6,CC2D2A,SPARCL1,ALCAM,ABCD2,ANK1,EP400,USP28,PPFIA1,PKP4,APC,TNRC6C,USP37,APP,SEMA4G,CDK13,ASPH,NUMB,SLC4A4,ATP1B3,ATP2B1,ATP2B2,N4BP2L1,BACH1,DST,BSN,LRBA,CDC42,LRRFIP1,MAGI1,CFL2,CHN2,ZFYVE9,QKI,MAP4K4,CNN3,AKAP6,RCHY1,RTTN,CREM,TENM4,ATRNL1,FAM169A,DZIP3,PHF14,CCDC144A,BOC,RIPOR2,ARHGAP24,KIAA0586,KLHL3,G3BP2,DLG2,GRIN3A,DMD,DTNA,MAMLD1,DYRK1A,AASDH,SGK2,FCF1,EFNA3,GOLGA7,ELAVL2,STARD3NL,CALCRL,MFSD10,IGSF6,DNAJC27,RASL12,F3,SH3YL1,SCML2,TOMM40L,TESK2,SEC24B,NBEA,UFM1,NPTN,CAMKK2,TBR1,AP4B1,NRG3,GAB1,GABRB1,ZMYND11,ERAP1,SIGLEC8,GATM,GLS,TNRC6A,MSL3,GPD2,PCLO,RFFL,GRM7,MAP4K5,RASSF8,HMGB1,ZDHHC15,SCIN,ZNF385B,KCNA1,KCND1,KCNJ16,IPO5,MARK1,MAT2A,MATN2,MBNL1,LRP1B,MEST,KCTD6,MOBP,MOV10,TAGLN3,MTTP,LAYN,NELL1,NEK1,NEUROD1,NEUROD2,NFE2L2,NNAT,NOVA1,CCSER2,PLIN1,HMGCLL1,PMP2,LRP12,EPB41L4B,PPP3CA,KANSL1,PKN2,EPDR1,HYDIN,SYTL2,GON4L,PTCH1,BDNF-AS,ZSCAN32,PTPRD,ZSCAN2,USP47,FAM66C,FAM184A,DBX2,SLC6A15,RIC8B,ROBO2,RORB,EPHA10,ABCA11P,RYR3,TMEM156,SATB1,SCN3A,IL17RB,SFPQ,MRAS,ITSN1,FAM102A,FNDC3A,SLC1A6,FAM81A,WDR47,RAB3GAP1,ARHGEF40,SLC14A1,BTBD7,GKAP1,SNAP25,MBD5,CMTR2,SNRPN,UNC80,ENKUR,ZC3H13,RBM26,TROVE2,MPRIP,PLCB1,COBL,DMXL2,SATB2,OBSL1,RNF216P1,ZFPM2,HHIP,SLC44A1,TJP1,HEY2,SYNPO2,TRPC3,TRPS1,ZMYND8,SSBP2,RFTN2,TMEFF2,SGK3,PITPNB,FLRT2,BCL2L13,CCDC136,WIPF1,PCDH20,ZNF28,SPHK2,ZNF138,LAMP5,WNK1,CADM2,PRDM2,TMEM178A,NAV2,PDSS2,RGS7BP,FZD3,JMJD1C" MicroRNA hsa-miR-3154:mirSVR_highEffct hsa-miR-3154:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-95 6.08E-92 6.20E-95 5.71E-94 239 968 "XKR4,KLHL32,BRAP,SORCS1,SPOP,PCDH10,FAM135A,ALS2,APP,AQP4,MIER1,NCOA1,NOL4,ATP6V1G2,DCAF5,SYNJ1,ARHGEF7,CALB1,CBR1,USP2,TMEM257,CD38,ZBED1,CDC42,ZMYM4,ARHGAP33,TIGD7,UBE2L6,ZFYVE9,NRXN1,ARHGEF6,CNTFR,COL9A2,SLC4A8,ZFP28,PNKD,SEC31B,CLOCK,CRYBB1,GDA,CS,CSF2RA,FEZ2,ARHGEF10,CSNK1E,APPL1,PHF14,NRSN1,CCDC144A,HDAC9,GPRASP1,DCAF8,ZNF337,LIN54,SPOCK2,PABPC5,PITPNC1,HP1BP3,C2CD2L,CEP170,ZC3H11A,SMG7,RABGAP1L,TMCC2,DLG4,DMD,CPEB2,E2F5,EBF1,HIPK3,CACNG7,EFNB3,ELAVL4,PAN3,EIF1,EPB41L1,EPB41L2,GPHN,SRRM1,ETV1,RTN3,PTK2B,POLR1B,FGF12,FGR,FHL1,IP6K2,NELFCD,NBEA,TMEM107,PRELID3A,STAU2,ZNF512,PHYHIPL,GABBR1,AHCYL1,GALC,JPH4,ERAP1,GGTA1P,GLS,MSL3,PCDH11X,ZNF638,GP1BB,CCDC184,EML4,RAPGEF4,GRIA4,PLCD4,GRIK2,AP4S1,ADAMTS6,NXPH2,KLF12,HSD17B1,DOCK7,LRRCC1,ZNF678,LDLRAD3,MEIS1,AFDN,MN1,MOBP,MOG,MYO9A,RTL5,NCAM1,NCF2,NDUFA5,RCOR2,NEUROD1,NINJ2,CNOT4,DNHD1,NUCB2,GLIPR1L2,PCDH9,PCMT1,PDPK1,HERC2P3,ST8SIA5,PURG,PNMA3,C11orf49,PMP22,POU3F4,PPM1B,PPP2R2B,PTPA,PPP3CA,MAPK7,MAPK9,RELN,KLK6,APTX,OCIAD1,TMEM145,PID1,RAD17,DPF2,PRRT2,MORC4,GTDC1,RGR,RGS4,RGS7,KCTD17,SEC61A2,RIC8B,RNASEL,RPRD1A,SETD5,EXD2,UEVLD,ATP8B4,PRR5L,ZNF568,AMER2,ATXN2,ITSN1,CCDC88A,SLC11A1,SLCO1A2,SLIT1,SMARCC2,SMARCD3,RCOR3,ANKRD36,LIMCH1,RIMS1,SON,SP2,DDN,CLASP2,ZC4H2,MPRIP,ZSCAN29,VAMP1,SYT1,ANKRD28,MTCL1,SEMA4A,TBX15,DMXL2,ZEB1,RPGRIP1L,FRYL,TMEM9,ACTR6,TMPO,TNR,NPL,ELP5,AMACR,RFTN2,TST,FAM155A,UBE3A,FAM181B,PLPPR2,VGF,MEAF6,KLC2,RICTOR,SF1,GPR158-AS1,NDRG4,ZNF177,ZNF189,MEIS3,PRDM2,PRDM10,LMAN2L,PCDH15,ZNF248,NHSL1,PIANP,SENP7" MicroRNA hsa-miR-3147:mirSVR_lowEffct hsa-miR-3147:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-95 7.26E-92 7.39E-95 6.81E-94 275 1271 "VWA5B2,RALGAPA1,ABAT,SYS1,XKR4,PLEKHH1,UNC5A,SNX30,ADRA1D,FAHD2CP,BEND6,MTA3,AP2A2,WDR35,CC2D2A,ADGRF5,CEP126,MARCH4,LTBP4,EP400,SUGT1P4-STRA6LP-CCDC180,APBB1,ALS2,TNRC6C,SHTN1,SLC4A4,NOL4,BACH1,MIR9-3HG,P2RX6,ARHGAP33,NOG,NUMBL,ADGRG1,SRSF11,ASIC3,SYNPR,RAB3C,CPNE6,SRP14-AS1,HECTD1,AKAP7,ARMC8,ABI3BP,SEC31B,C2CD2,TRIM69,CS,SEC24C,ATRNL1,SOCS5,PDE4DIP,SLITRK5,SDC3,PLCXD3,EDRF1,SEC14L5,NOS1AP,HDAC9,ARHGAP32,SNPH,EARS2,LONRF1,MAML1,ARMCX4,YTHDC1,DNAJC6,C8orf34,RUSC2,FBXO25,DDX46,SV2A,SGSM2,WDR20,DLG3,GRIN3A,DNM1,DTNA,TOM1,DYRK1A,DNM1L,AASDH,EDNRB,EGFR,RASA4,EPB41,NCALD,IGSF6,SPEG,SIRPB1,F5,CLVS1,WAC,FCGR3A,TOMM40L,ZNF589,FOXG1,ATP13A4,FLT1,C2orf88,DPYSL4,FAM49B,STAMBP,RASL10A,TPPP3,BRSK1,ZMAT1,GAD2,CYP46A1,GFRA2,CSDC2,PPARGC1A,KIRREL3,LUZP2,WDFY3-AS2,ADGRA3,TDRKH,GPR22,LPAR4,ATP2B1-AS1,ADAMTS13,ADAMTS8,ADAMTS6,GUCY1A1,HAS2,PADI2,BACH2,SHISA6,FAM95B1,C2orf72,SOWAHA,LRRC25,KIAA1755,TJAP1,USP54,LIX1,KCNC1,GPR62,KCNK2,ZFYVE27,MBD1,LDLRAD3,MDM4,MEIS2,MOBP,MSI1,MSR1,PTOV1,LYRM9,MYT1,NAP1L1,SLCO1C1,NOVA1,OPRL1,ZNF827,SNTG1,PCSK5,PDE2A,GPR85,ZNF655,HMGCLL1,LRP12,NECAB2,ING3,EPDR1,BCAS3,PIGG,NCR3LG1,TMEM260,FAM120C,PEX5,ZSCAN2,ZNF615,TMEM231,PID1,FAM66C,RASGRF1,PRRT2,GTDC1,RFX4,UBR7,RGS12,RIT2,MRPS18A,RAVER2,ROBO2,RPL15,SPIN3,LRRK2,ABCA11P,ST6GALNAC6,SEMA6D,ATXN2,ITSN1,SH3GL3,MYO18A,FBXO11,CCDC92,DZIP1,LIMS2,SLC6A8,SLC8A1,TRIM67,SLN,CDK5RAP2,SNRPN,USP33,SON,WDTC1,SOX2,TNIK,KIF21B,KDM3A,CAND2,ZC3H13,PBLD,SAMSN1,NKAIN2,INKA2,STAU1,RGL1,SYNE2,RHBDL3,VPS13A,NUDT10,SYN1,SYN2,IQCE,VWA3A,EHBP1,NEU4,DMXL2,ZEB1,TPCN2,SYNE1,TMEM151B,PUM2,ARHGAP9,CYB561A3,RNF216P1,DICER1-AS1,DAAM2,R3HDM1,TPM4,METTL3,AMACR,TRPC3,ZMYND8,DCBLD1,UBE3A,OSBP2,BEST1,GUSBP1,ZNF74,NDRG4,ZNF177,EML6,ZNF195,UPF3A,NT5M,DNALI1,STOX2,TMEM178A,SCG2,NAV3,SNX27,WNK3,C12orf4,RTN4,KAT6A,PHTF2,NUP214,VANGL2,ADAMTS10,NETO1" MicroRNA hsa-miR-1233:mirSVR_lowEffct hsa-miR-1233:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.01E-95 1.13E-91 1.15E-94 1.06E-93 288 1389 "KCNH8,SYN3,AS3MT,PSMG3-AS1,ADD1,SORCS1,ADRA1D,HFM1,C1QTNF3,ZNF687,PDZD4,FGD2,PHF12,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APAF1,KCNAB2,UPRT,AMER3,KIAA1614,MADD,ARRB1,PLA2G4C,CDK13,MARK4,ASPH,DACT3,PCDHGB4,NUMB,NOL4,DPY19L3,TTLL9,NAE1,BTRC,HAP1,TRIM41,CAST,RUNX1T1,USP6,TMEM257,CDH2,DLGAP2,TIGD7,IGFN1,UBE2L6,NMT2,TJP2,HECTD1,COL11A2,RCHY1,COX4I1,CHD1L,CREB5,GDA,SNCAIP,ARHGEF10,MICAL2,VCAN,PLXNA4,GREB1,CFAP61,CTNND2,EDRF1,FAM131B,CX3CR1,DOCK4,ARHGAP24,ZNF337,DAPK1,IP6K1,AIF1L,ZBTB24,KIAA0319,ALKBH8,RHOBTB1,SACS,NTM,CCDC3,DLX1,DMPK,HS3ST2,DYRK1A,ABCC5,E2F6,PHC2,OPTN,SH3GLB1,SUGP2,EBI3,VPS13B,COQ7,ZNF391,GMPR2,EZH1,FAM198B,DLC1,FCGR1A,TESK2,ZNF589,GTF2IRD2,OLFM1,FGF11,EFCAB2,POMT1,STAMBP,NPTN,ATP6V1H,ERGIC3,DACH2,GPR153,B3GAT1,DKK3,ZNF44,AHCYL1,KIAA1841,CPLX1,GCNT2,GPR162,COPS8,RAB30,TDRKH,DIDO1,GRIK4,ADAMTS13,GRM2,ZNF496,LINC01551,AP4S1,ATOH8,FRMD3,ATXN2L,SYNPO,HMGCR,C9orf129,ZDHHC15,DHX35,MSL1,FAM95B1,LINC00667,ZNF546,LRRC25,KCNA6,GPR62,KCNJ11,KIF5A,KLRC2,CYP27C1,VWA5A,MAN2A2,ZFYVE27,MAOB,MAP4,MAT2A,CHIC1,SCAMP5,MID1,FXYD6,NBL1,RCOR2,NME4,NODAL,NUCB2,TBC1D25,CLDN11,GLIPR1L2,PCDHGC3,PCDH9,CDK18,PDCD2,PDGFRA,FAM218A,GPSM2,ANKRD16,TMEM235,PPP2R5E,PKIA,PRKCZ,MAPK4,MAPK10,DCHS2,PSD,SIDT1,GON4L,PTPRE,PEX5,RIPOR1,ZSCAN2,TMEM231,RAB3IL1,RASGRF1,RET,RFX3,RNF220,RNASEL,ROBO2,RORB,SNX22,RPL15,BAALC,MCMBP,ADAL,ABCA11P,KCNIP2,CSRNP3,LRRTM4,LINC00461,ELMOD1,SEC14L1,SOX6,CASC3,SGK1,KIF21A,FERMT1,DOCK10,NTNG1,BCAN,NUBPL,PAAF1,ZNF365,DHX30,FAM214B,LRRC55,ARFGAP1,CXXC4,ZNF667,SMARCA4,FAM126B,SCN3B,WDTC1,KIF21B,BDP1,IQSEC2,DDN,NFASC,C11orf87,STAU1,SYN2,EXOC7,CAMSAP2,UNC5D,TMEM136,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,AKNA,PMS2CL,SLC44A1,ZFP91,TNR,C9orf85,SMUG1,TRIO,TRO,FAM155A,UGT8,PLEKHH2,WIPF1,NSD2,RICTOR,LGI4,ATP6V0E2,MKRN3,ZBTB38,DPYSL5,ANKS1B,LAMP5,LINC02210,SIGLEC10,URM1,PPP1R3F,LINC00632,MPPE1,MVB12B,PARP11,TMEM63C,FBXO36,DPF3,FAM198A" MicroRNA hsa-miR-548g:PITA hsa-miR-548g:PITA_TOP PITA 2.16E-95 1.21E-91 1.23E-94 1.14E-93 196 649 "KCNH8,ACTN1,ARID1A,CSMD3,FMNL2,USP31,PWWP2A,LRFN2,HECW2,PCDH19,ALCAM,CDC42BPA,ANK3,APAF1,GPAM,LRRC4C,TMEFF1,ARHGAP5,CDK13,NCOA1,SLC4A4,ATP2A2,SYNJ1,FUBP1,CACNA1I,NIPA1,LDLRAD4,CACNB2,CACNB4,CALB1,CALM1,CLDN10,CLGN,SRSF11,SOCS6,LHX2,FAM19A5,QKI,NIPBL,CNN3,CLOCK,CREM,CREB5,CRMP1,CSNK1G3,ATRNL1,PLCXD3,GAPVD1,TOX,LONRF1,MATR3,DNAJC6,HP1BP3,CEP170,MAGI2,G3BP2,DUSP9,DYRK1A,ABCC5,EDN3,RBM12,KMT5B,ABI2,PLEKHA1,RGS17,STARD3NL,TAOK3,SUCO,FOXF2,FUT9,B3GAT1,STAG2,AHDC1,PCDH17,TCERG1,TNRC6A,FERMT2,GPT2,GPM6A,CECR2,GRB10,GRIA2,GRM7,PTPRT,FAM19A2,RNF165,PSIP1,ADAMTS6,MAP4K5,ZHX1,KLF12,BACH2,HLF,NEGR1,AGFG1,DHX35,C5orf24,BRINP3,ITGAV,MARK1,MAT2A,MEIS1,MID1,AFF1,MXI1,MYO5A,NEXMIF,NCAM1,NEFM,NRCAM,KSR2,GPR88,PCMT1,PCSK1,CDK14,PIK3R1,RETREG1,KCTD15,PPARA,PPP2R5C,PPP2R5E,PPP3CA,KANSL1,PKN2,RELN,PTCH1,PTPRD,FAM120C,RAB5B,TMEM255A,ARID4A,ZYG11B,FIGN,ZFHX4,ROBO2,RORB,FBXW7,ACER3,CSRNP3,ATXN1,TRA2B,CPEB3,CHD9,FBXO11,FNDC3A,PPP4R3A,EPN2,WDR47,CCDC88A,ATF7IP,CPEB4,RIMS1,TMCC1,SON,WDTC1,MYT1L,SOX2,SOX11,LMO3,SRPK2,SS18,STAU1,ANKRD12,CAMSAP2,FBXW11,TCF12,SYNE1,DOCK9,PSD3,TMEM121,TJP1,ZFP91,ERCC6L2,R3HDM1,RBFOX2,RPRM,EIF4ENIF1,FLRT2,NSD2,PCDH20,ZBTB14,ZNF711,LYPD6,PMEPA1,EMSY,STOX2,PRDM8,NAV3,SLC17A7,PCBP4,HNRNPA3,PHTF2,JMJD1C,VANGL2,SOCS4,JPH3" MicroRNA hsa-miR-1274b:mirSVR_lowEffct hsa-miR-1274b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.75E-95 1.55E-91 1.57E-94 1.44E-93 257 1120 "NBAT1,KDM5D,GPRIN1,CSMD3,SLC44A5,MTUS1,RTL9,AK2,ALAD,SYT13,AMPD2,CNIH2,SUGT1P4-STRA6LP-CCDC180,ANXA7,CACHD1,CDK10,SPTBN4,ARHGDIG,PLA2G4C,BRINP2,RASL11B,ADAM23,SGCE,NIPA1,CAMK2B,SPAG9,CERS5,SOCS6,PLEKHB1,NRXN3,NRXN1,FAM189A2,DNAJB5,COL4A5,AKAP5,ABI3BP,COX4I1,AHCTF1,RTTN,RBM39,NCOR1,NCOR2,SNCAIP,CSNK1G3,ATRNL1,VAC14-AS1,UBXN2A,CFAP61,NRSN1,EDRF1,ARHGAP32,ZFYVE16,AIF1L,ARMCX4,ZEB2,ZC3H11A,SV2B,SRGAP3,SGSM2,G3BP2,DOCK2,DNAJB6,USH1C,FCF1,CNNM1,FAM13A,EGFR,EGR3,SORBS3,TMEM35A,VPS13B,EPB41L1,EPB41L2,EPHA5,DENND4A,CDKL3,MRPL10,FAM198B,WAC,FABP7,CACNG2,ATP8A1,ST3GAL6,TESK2,PPP1R1B,FER,FGF1,FGF12,BAIAP2,JKAMP,STAU2,ZMYND11,TUBGCP4,GJB1,GK,GLS,LUZP2,LPAR4,RAPGEF4,DIDO1,PLCD4,GRIK2,GRIK3,GRM5,WIF1,NXPH2,GPR45,BACH2,SYNPO,ZDHHC15,HTR5A,DOCK7,KIAA1755,SCIN,SLC6A17,ZNF385B,LRRTM3,SLC35G1,KCNK1,KCNN2,CREG2,L1CAM,LAMP2,LIMS1,HECTD2,ARHGAP12,MAN2A2,ZFYVE27,MAP4,MBD1,MBP,CHIC1,XRRA1,MYO9A,NCAM2,NELL2,ALDH1L2,NFIX,NOVA1,HCN1,IGSF11,PAK3,PCDH9,CYTL1,CDK14,ZNF655,PLP1,PNMA3,C11orf49,MAPKAP1,LRP12,ING3,RETREG2,POLR2F,PPM1B,PPP2R2C,EPDR1,VPS13C,SLC22A23,SIDT1,BDNF-AS,PTK2,PTN,TMEM260,PTPRG,ZSCAN2,CCDC40,RAD51D,SH3TC2,BSDC1,GTDC1,RGS4,EXD2,GSTCD,KIRREL1,TMEM206,RPE,MCMBP,TCP11L1,LRRK2,RXRG,SCN3A,TNFRSF19,ASIC4,ELMOD1,SFPQ,ITSN1,ASAP3,FUZ,AMBRA1,BCAN,ZNF365,FAM81A,PPP4R3A,RUFY2,FAM214B,KANSL3,LRRC55,TMEM132D,ELMO2,SLCO1A2,SNAP25,KIF13A,UNC80,SON,PDZD2,NMNAT2,GLT8D1,KDM4C,KIF1B,TSPYL2,CAMTA2,NKAIN2,ERBIN,SEPT3,AJAP1,FGD4,PRRC2C,TACC1,UNC5D,ADGRL3,TBCEL,TBL1X,ATMIN,SATB2,TCF7,WASHC4,TNS2,HIF3A,CRB1,AP4E1,ZFP91,CSMD1,PRMT8,CADM1,UBE2H,VAV2,BEST1,WIPF1,XRCC4,ZFP37,ZNF711,ZNF19,ZNF154,ZNF213,EMSY,LINC02210,STOX2,TUBA1A,NAV2,PAK5,PHTF2,CASC15,SNX14,IFT88,RNF146,LAS1L" MicroRNA hsa-miR-513a-5p:mirSVR_highEffct hsa-miR-513a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.47E-95 1.95E-91 1.97E-94 1.82E-93 236 949 "CLK4,ADD3,SLC24A4,RTL9,AK2,LRRC7,AMPD3,LRCH2,ANK3,LCORL,PHF12,PPFIA1,SFMBT2,MARCH3,ATP6V1G2,SEC11C,ZNF599,SYNJ1,ARHGEF7,CACNA1B,KALRN,CAMK2D,CAST,RUNX1T1,METTL6,USP2,CD86,ENTPD6,ZMYM4,LOC730101,JAM2,NDST3,NRXN1,FAM189A2,DNAJB5,QKI,TMEM155,IQCK,ARMC8,SLC4A7,NCOR1,TRIM69,ARHGEF10,ATRNL1,VAC14-AS1,CTH,CTNND1,NRSN1,PPP6R2,KIAA0586,DGKB,JAKMIP2,ZEB2,CNIH3,MAGI2,RHOBTB1,WDR20,DLG2,EXOG,DPYSL2,RCAN1,GNE,ARRDC4,DTNA,FAM78B,MAMLD1,EDIL3,SGK2,RASGRP1,EGFR,ELAVL2,DCTN4,EPB41L2,EPHA5,KCNMB2,EPS8,DNAJC27,TLR7,ADGRV1,EYA1,TMEM132C,TESK2,MED12L,OLFM1,FGF14,MEX3B,IP6K2,IQCG,DCTN2,PDLIM5,USP21,NPTN,SARAF,TBR1,AP4B1,ZNF44,CHL1,GALR1,IQGAP2,ERAP1,ZNF559,DISC1,NEU3,SULT1C4,PPARGC1A,MALT1,DHRS4,ZNF638,PSRC1,LILRA1,RAPGEF4,GRB10,C1QL4,NR3C1,FAM19A2,ZBTB49,LINC01551,MAP4K5,C2orf72,IL6ST,INPP5B,KCND2,MAP2,MARK1,AQP11,MID1,MOBP,ERICH3,ZNF680,MTTP,NKX2-2,NODAL,IGSF11,PCDH9,CDK14,ABCB1,GDAP1L1,ZNF655,A2ML1,SNX10,XRN1,C11orf49,PDZRN4,SEPT4,SLC36A4,POU3F2,MAPK7,MAPK9,MASP1,WBP1L,SNRK,PXK,PEX5,USP47,FAM184A,VEPH1,KHDRBS2,RFX3,RGS3,RGS12,CCDC82,ALG9,RORB,NEK11,BAALC,LRRK2,NCBP3,FAM192A,PRCD,SUPT20H,SCG5,PPP1R9A,SH3GL3,SLC6A11,KBTBD4,NAPB,SNAP25,ZNF415,SNRPN,MYCBP2,MCF2L2,NPAS3,CLSTN2,SYN2,SYT1,COBL,MTCL1,DNMBP,UNC5D,ADGRL3,TBCEL,KLHL4,EHBP1,TRIM2,SYNE1,FAM189A1,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,C18orf54,HHIP,GZF1,TIE1,FAM124A,C9orf85,ZNF346,PRMT8,STXBP4,DCBLD1,SSBP2,UBE2H,DNAJC12,MEAF6,NSD2,RICTOR,XPO1,LYPD6,ZNF189,DPYSL5,PLPPR5,MAP3K12,EMSY,RNF103,MPPE1,C12orf4,PDSS2,JMJD1C,TRAM2-AS1,RNF146,CBLN2,PRRT4" MicroRNA hsa-miR-375:mirSVR_lowEffct hsa-miR-375:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.49E-95 1.96E-91 1.98E-94 1.83E-93 239 973 "ABHD6,AS3MT,KLHL32,SORCS1,PLEKHH1,GRAMD1B,AGT,ADGRF5,SPOP,FAM135A,MAP4K3,PKP4,KCNAB2,PPFIA3,LGR5,AQP4,TMEM263,TMEFF1,ZFYVE28,PDE8B,CAPRIN2,ZBTB10,CCDC181,ATP2B3,GPR146,SCAPER,KALRN,USP6,RGN,LRRFIP1,CDH18,MAGI1,NOG,CHN2,NRXN1,TPP1,QKI,NIPBL,FHL5,AKAP7,ARMC8,AKAP6,BAG4,CNRIP1,CP,SEC31B,CDC42BPB,CREM,ANKRD44,CSNK1E,SOCS5,DZIP3,PUM1,CX3CR1,CYBB,DOCK4,KATNAL2,ZFYVE16,MATR3,ARMCX4,DCC,ZEB2,GSDME,SNAP91,SPOCK3,WDR20,DMD,DPYSL2,DNM1L,EDIL3,EDN3,EFNB3,PHF20L1,EGFR,ELAVL2,USPL1,RABEPK,SRRM1,PIPOX,ABCA8,ACSL4,FER,KIAA1109,OLFM1,SUCO,PCYOX1,NELFCD,COQ5,EFCAB2,NBEA,APOPT1,KHDRBS3,PNMA2,TBR1,AP4B1,PHYHIPL,FAM120B,IP6K3,GAP43,TMEM8B,C15orf41,MYOZ2,SULT1C4,AHDC1,PPARGC1A,HPGDS,PCDH11X,GNAO1,PSRC1,GPM6B,STON1,LPAR4,STMN2,GRIA2,GRIA4,GRIK2,GRIK3,GRM8,SOX21,PSIP1,MAEL,IGSF21,NXPH2,HMX1,HNF4G,ZIC5,PLD5,INSM1,ZNF385B,JAK2,KCNJ3,STXBP5,LAMA2,LIG4,VWA5A,HECTD2,MATN2,SYT9,LRP1B,MEIS1,POC1B,MITF,CD200,CCDC80,ADAM22,NCAM1,NEUROD1,NOVA1,NUCB2,OGG1,OXTR,PDE4A,CYTL1,NLGN3,PCDH18,PURG,PPP2R5E,PPP3CC,RAB39A,DCHS2,SNRK,MDGA2,CNTLN,PTCH1,ANKHD1,PTPRE,TTC13,ZYG11B,ZMAT4,REV3L,RGS7,PBRM1,RNASEL,RPRD1A,ZFHX4,CARF,CCDC102B,NCBP3,CCDC112,SCP2,ITSN1,SH3GL3,CNKSR2,RUFY2,NAPB,ATF7IP,SLC22A4,DMRTC1,ANKRD36,LIMCH1,SNRPN,MYO16,WDTC1,MYCBP2,KDM4C,C11orf87,SAMSN1,SSTR1,ERBIN,NXT2,KLHL7,VAMP1,TACC1,MTCL1,CAMTA1,ANO4,ZEB1,TCF12,PCDHB6,OBSL1,TF,FAM200B,AKTIP,ZFP91,ERCC6L2,R3HDM1,TPM1,NPL,C9orf85,NTSR2,SGK3,RPRM,FAM155A,UBE2H,UBE3A,SLAIN1,WRN,PCDH20,ZIC1,ZIC3,PLPPR5,DNALI1,RNF103,SLC17A6,DOCK8,TRAM2-AS1,KLHDC1,FRMD6,NETO1" MicroRNA hsa-miR-302f:mirSVR_highEffct hsa-miR-302f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-95 1.98E-91 2.00E-94 1.85E-93 247 1038 "ACTN2,CSMD2,FMNL2,DSCAML1,SLITRK1,ADD3,SORCS1,KIDINS220,BEND6,HECW2,OSBPL1A,ALCAM,LRCH2,ANK3,LCORL,PPFIA1,PKP4,ALS2,VAT1L,CAPRIN2,ASPH,DDX3Y,STX16,ATP2B2,SNAI3-AS1,LINC00847,SEC11C,DST,ST3GAL5,JAZF1,IL33,THSD7A,PTBP2,CBR1,LRBA,SRSF11,CHN2,B4GALT6,RAB28,PLAA,TJP2,FHL5,AKAP7,COL4A5,SLC4A7,COX4I1,TOGARAM2,SLC35F1,CREM,CRHBP,AKAP12,HAPLN1,FEZ1,ATRNL1,PHF14,PNPLA8,CTH,CTNND1,NRSN1,GPRASP1,FGFR1OP2,ARHGAP24,HDAC4,IST1,C8orf34,ZEB2,KIAA0319,MAGI2,AK5,USP3,DYNC1I1,NR1D2,ABI1,DNM1L,EDNRA,SEMA3D,KLHL5,FAM13A,PHF20L1,GOLGA7,TENM1,RGS17,EML1,DLC1,CEP78,CHST15,FER,CAP2,AGAP2,SGIP1,KHDRBS3,STAU2,PNMA2,GABRB1,GABRG2,ZMYND11,C15orf41,KIAA1841,MYOZ2,GCNT2,AHDC1,RAB30,TOX3,PRUNE2,GPM6B,GPR12,GRIA1,BVES,ADAMTS6,MAP4K5,SHISA6,HTR2A,INPP1,LRRTM3,SLC35G1,KIF5A,L1CAM,PAXBP1,NCOA7,PACRG,MARK3,MBD1,MEIS1,WDR49,MSR1,ZNF92,MYH7,BEX5,ZC3H12B,NDUFA5,NEK1,NEUROD1,NF1,OTOGL,OPA1,PAK3,ETFRF1,PDE4D,PDGFRA,BEST3,ZFYVE21,ST8SIA5,PLEC,MAPKAP1,SPATA6,RETREG2,PPM1B,PPP2R2B,CRLS1,PRPSAP2,MDGA2,PTN,PTPRG,PTPRZ1,PID1,CEP97,CCDC40,MSANTD2,RDX,SLC6A15,ERI2,RFX4,TTLL7,NUDT11,CCDC82,CARF,ROBO2,RORB,RPE65,GLDN,LGR4,CCDC112,SATB1,LRRTM4,LINC00461,NLGN4Y,ZFP30,DOCK10,SHC4,NLGN1,PREX2,SLC6A1,SHANK2,SLC15A2,CDK5RAP2,SMARCE1,RCOR3,CMTR2,SNRPN,PDZRN3,UNC80,SOX5,BDP1,SP2,MYCBP2,SPP1,NPAS3,RAP1GAP2,NEK4,SEPT3,AJAP1,NECAB1,FGD4,VPS13A,SYT4,POPDC3,UNC5D,ADGRL3,TMEM136,ATMIN,TCF7L2,RNF175,TEX15,SIK3,CRB1,ITGB3BP,LEFTY2,SLC44A1,HEY2,C5orf64,RGMB,PPIL6,DCBLD1,CLHC1,UBE2H,GORASP1,CCDC14,P2RY12,CLDND1,GUSBP1,MICU3,KCNT2,MKRN3,SPHK2,REEP1,FSTL5,SYNC,WNK1,PRDM2,EVI5,CAB39L,GOPC,FAM13C,PHTF2,TIGD6,MSRB3,CBLN2" MicroRNA hsa-miR-92b:mirSVR_highEffct hsa-miR-92b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.56E-95 2.00E-91 2.02E-94 1.86E-93 225 863 "SYN3,NCKAP5,CSMD2,CSMD3,DSCAML1,TMCC3,SLC12A5,GRAMD1B,KIAA1211,MARCH4,FAM135A,PITPNM2,DPP10,ANK3,USP28,MIER1,ASPH,DDX3Y,ATP2A2,MTMR9,B3GALT2,ADAM23,ADGRB3,MPDZ,HCN2,CDK5R1,SYNJ1,CACNA1I,OSGIN2,CA8,KALRN,CAMK2A,MTMR7,AIFM1,CDC27,CDH10,SOCS6,CHM,NDST3,NRXN3,HECTD1,NIPBL,TMEM155,CNRIP1,HS3ST5,FAM171B,CRHBP,SLC32A1,LRIG1,ATRNL1,SOCS5,SLITRK5,ERC2,APPL1,EDRF1,CCDC144A,DOCK4,HDAC9,SPOCK2,PITPNC1,ZNF804A,ZEB2,PLPPR4,G3BP2,CDON,CPEB2,ARRDC4,EDNRA,EDNRB,ANKRD46,HIPK3,FRY,KMT5B,PLEKHA1,RGS17,PCOLCE2,EPHB1,KCNMB2,TMEM74,KIAA1109,POLK,ATP13A4,SLC37A3,TACC2,NPTN,ATP6V1H,ZNF605,NSG1,ABLIM2,DKK3,GAA,B4GALNT1,IQGAP2,GAP43,GHR,SPIN1,GLYR1,PCDH11X,CNDP1,GPD2,GPM6A,TPPP,GRIA1,DIDO1,RFFL,GRM1,GRM7,HAS2,MIER3,SCRG1,HNMT,MSL1,RBPJ,SLC6A17,ITGAV,C2CD4C,KCNK1,LAMP2,LMO2,SMAD9,PIK3AP1,MARK1,MATN2,LRP1B,SESN3,MSR1,MYO5A,P2RY13,NEFM,NEFH,NF1,NOVA1,SMIM11A,CLDN11,GPR137C,PDE1A,SLC10A4,PIK3R1,CCSER2,SNX10,ZFYVE21,JAKMIP1,TRHDE,STRN3,ING3,CEP41,TMEM260,PTPRD,PTPRO,PEX5,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,LGI2,SETD5,ROBO1,ROBO2,RORB,RPE65,RPL15,FBXW7,ABCA11P,AP1AR,SATB1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CNKSR2,NUBPL,ZNF430,SLC12A2,CPEB4,DMRTC1,CDK5RAP2,TTC17,PALLD,UNC80,PDZD2,MYCBP2,TEX2,KIF1B,NPAS3,PBLD,ITPRID2,ELOVL4,RGL1,FGD4,ZFR2,SYN2,SYPL1,SYT1,SYT4,CAMTA1,ANO4,DOCK9,SIK3,HHIP,KCTD2,TPM4,SYNPO2,TRIO,SGK3,PCDH20,ZNF711,ZNF17,ZNF24,KCNT2,FMN2,MFF,LRP8,EVI5,RNF103,NAV3,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,SLC39A12,FXR1,SLC4A10" MicroRNA hsa-miR-182*:mirSVR_lowEffct hsa-miR-182*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.78E-95 2.13E-91 2.14E-94 1.98E-93 264 1181 "DPF1,ABAT,CLK4,EMILIN3,DSCAML1,GALNT13,BEND6,MTUS1,GPR158,HFM1,SEMA6A,BCAR3,PCDH10,GOLGA7B,OGT,PKP4,CACHD1,MADD,MARCH3,BRINP2,TMEM108,CCDC181,ATP2B1,RNF182,B3GALT2,RIPK1,ADAM23,BCHE,DNAJC27-AS1,ARHGEF7,CA8,KALRN,VSTM2A,CH25H,MAP7,CD86,PLAA,CLTC,TJP2,FAM19A5,TMEM155,CNN3,CNR1,IQCK,PCYT1B,FAM149A,CABP1,ZNF385A,PREPL,RBM39,RNF14,ABCG1,SNCAIP,CSF1R,CSF2RA,ARHGEF10,IPCEF1,PLXNA4,PLCXD3,CTNND1,CTNND2,ZSCAN23,EDRF1,CCDC144A,MYADM,ARHGAP24,AIF1L,DNAL1,YTHDC1,MYEF2,KIAA0319,MAGI2,SPOCK3,SRGAP3,MTX3,DMTF1,CASP8AP2,DNAJB6,ABCC9,SNX29,FRY,EFNA3,RBM12,EGFR,EIF4G2,TENM1,MRNIP,KCNMB2,ACSL4,ZIC4,FER,FGF1,FGF12,TMEM164,FGR,SEC23B,SYNCRIP,FOXO3,ATP13A4,FLT1,PSD2,NBEA,UFM1,CELF1,DACH2,TBR1,PHYHIPL,GABRG2,GAD1,FAM120B,DISC1,ATP8A2,ACSS1,LRRC37A6P,KIAA1841,HPGDS,LUZP2,GPD2,GPM6B,LPAR4,GPR37,PCLO,RFFL,NR3C1,BVES,PSIP1,UBE2QL1,PADI2,ZHX1,MIER3,GABARAPL2,OPALIN,SHISA6,EID2B,MSL1,ZIC5,DOCK7,PLD5,INSM1,ZNF385B,KCNJ10,KCNJ16,LAMP2,INSYN2,PPM1L,XRRA1,SAMD5,SESN3,BLOC1S2,MSR1,MT3,TCEAL5,NEUROD1,NHLH1,SMIM11A,HCN1,PAK3,PBX1,PCSK1,PDE3B,PDGFRA,PDPK1,PIK3C2A,JAKMIP1,HMGCLL1,PMP2,SCHIP1,SPATA6,EPB41L4B,PRKACB,SAMD9,MDGA2,PIGG,CNTLN,PLPPR1,PTK2,SPDL1,PTPRB,PID1,ZNF793,FAM184A,RASGRF1,RBBP6,ERI2,RFX3,RGS7,SLC25A36,ROBO2,NEK11,LRRK2,LGR4,ZNF354C,SEMA6D,SBF1,ATXN7,FAM19A1,SCP2,KIF27,SH3BGR,AMBRA1,PPP4R3A,LRRC55,NAXD,ANKRD36,CMTR2,SOX3,EMC1,ZC3H13,KIF1B,RBM26,C11orf87,TAB2,ZSCAN29,KLHL7,FGD4,COBL,C12orf76,TBCEL,FBXW11,ZEB1,TRIM2,NAT16,AKNA,ARHGEF12,FRYL,HIF3A,TGFBR3,THBS4,KCTD2,PIK3R5,TPD52,TPM1,TPM3,C9orf85,PRMT8,STXBP4,RFTN2,TUB,USP1,BEST1,TBC1D15,CLDND1,ZIC3,MICU3,CFAP52,FMN2,NDRG4,LYPD6,ZNF142,ANKS1B,WNK1,SLC38A1,STOX2,HPS4,SEMA3B,MDH1B,PCDH15,CAB39L,ITM2C,PDSS2,PAK5,SNX14,DPF3,SLC4A10" MicroRNA hsa-miR-27a:PITA hsa-miR-27a:PITA_TOP PITA 4.10E-95 2.30E-91 2.32E-94 2.14E-93 198 665 "RALGAPA1,ELFN2,SLITRK1,ADCY6,PLEKHH1,USP31,ZNF608,TAOK1,SEMA6A,ALCAM,PITPNM2,ANK1,APAF1,APBA2,GPAM,PDE8B,NCOA1,DDX3Y,STX16,ATP2B1,RNF182,NOL4,DPY19L3,CACNA1A,CACNB2,C1orf52,CDC42,ZMYM4,MAGI1,FOXN3,SOCS6,KMT2C,DLGAP3,CLCN3,NRXN1,QKI,CNN3,CNR1,ARMC8,CABP1,ZNF385A,SLC35F1,PNKD,HAPLN1,RGS6,ERC2,EDRF1,LONRF1,SPATA2,POM121,SV2A,NR1D2,ARRDC4,EDNRA,MBNL2,EGR3,LPAR6,EIF5,ELAVL2,RGS17,TMEM35A,EML1,EN2,EPB41,EPB41L1,RCAN2,EYA1,KIAA1109,FGF12,FGF13,SUCO,ST6GALNAC3,DOT1L,BRSK1,GABRB3,CAB39,BRPF3,NEK6,CSDC2,RUNDC3A,GPD2,TMEM121B,GRIA4,GRIN2D,CIT,PTPRT,TMEM25,MFSD2A,FAM222A,ZHX1,MIER3,HNF4G,AGFG1,SOWAHA,ZIC5,KCNA6,KCNK2,LIFR,ARHGAP12,NCOA7,SMAD1,MARK1,AQP11,MATN3,CHIC1,MEIS2,KITLG,MN1,ERICH3,MSI1,MDGA1,MXI1,MYT1,NCAM1,ZC3H12B,NF1,NFE2L2,NOVA1,OPA1,ZNF827,CDK18,PDE3A,PDE3B,PDGFRA,PDPK1,CDIP1,POU3F2,PPARA,CEP41,PKIA,RELN,WBP1L,FAM120C,FAM184A,ENOX1,RET,ZFHX4,SETD5,ALG9,FBXW7,LGR4,HUNK,RXRA,NCBP3,SEMA6D,SMPD3,TRIM46,CASC3,FAM102A,PPM1E,CPEB3,MAGI3,CCDC92,SLC1A2,SLC6A1,SLC8A1,TET1,CPEB4,RCOR3,SNAP25,TMCC1,FAM126B,ZCCHC24,SOX11,KDM3A,TEX2,SRPK2,COLGALT2,SSTR1,LARP4,SS18,MAPK8IP3,SEPT8,STX1A,SYT1,CAMTA1,PDLIM2,SATB2,TRIM2,RPGRIP1L,WASHC4,WDR7,RALYL,FRYL,CSMD1,PRMT8,TSC1,CADM1,GORASP1,FLRT2,MICU3,TMEM237,WNK1,CA10,WIPF2,JMJD1C,VANGL2,ADAMTS10" MicroRNA hsa-miR-27b:PITA hsa-miR-27b:PITA_TOP PITA 4.10E-95 2.30E-91 2.32E-94 2.14E-93 198 665 "RALGAPA1,ELFN2,SLITRK1,ADCY6,PLEKHH1,USP31,ZNF608,TAOK1,SEMA6A,ALCAM,PITPNM2,ANK1,APAF1,APBA2,GPAM,PDE8B,NCOA1,DDX3Y,STX16,ATP2B1,RNF182,NOL4,DPY19L3,CACNA1A,CACNB2,C1orf52,CDC42,ZMYM4,MAGI1,FOXN3,SOCS6,KMT2C,DLGAP3,CLCN3,NRXN1,QKI,CNN3,CNR1,ARMC8,CABP1,ZNF385A,SLC35F1,PNKD,HAPLN1,RGS6,ERC2,EDRF1,LONRF1,SPATA2,POM121,SV2A,NR1D2,ARRDC4,EDNRA,MBNL2,EGR3,LPAR6,EIF5,ELAVL2,RGS17,TMEM35A,EML1,EN2,EPB41,EPB41L1,RCAN2,EYA1,KIAA1109,FGF12,FGF13,SUCO,ST6GALNAC3,DOT1L,BRSK1,GABRB3,CAB39,BRPF3,NEK6,CSDC2,RUNDC3A,GPD2,TMEM121B,GRIA4,GRIN2D,CIT,PTPRT,TMEM25,MFSD2A,FAM222A,ZHX1,MIER3,HNF4G,AGFG1,SOWAHA,ZIC5,KCNA6,KCNK2,LIFR,ARHGAP12,NCOA7,SMAD1,MARK1,AQP11,MATN3,CHIC1,MEIS2,KITLG,MN1,ERICH3,MSI1,MDGA1,MXI1,MYT1,NCAM1,ZC3H12B,NF1,NFE2L2,NOVA1,OPA1,ZNF827,CDK18,PDE3A,PDE3B,PDGFRA,PDPK1,CDIP1,POU3F2,PPARA,CEP41,PKIA,RELN,WBP1L,FAM120C,FAM184A,ENOX1,RET,ZFHX4,SETD5,ALG9,FBXW7,LGR4,HUNK,RXRA,NCBP3,SEMA6D,SMPD3,TRIM46,CASC3,FAM102A,PPM1E,CPEB3,MAGI3,CCDC92,SLC1A2,SLC6A1,SLC8A1,TET1,CPEB4,RCOR3,SNAP25,TMCC1,FAM126B,ZCCHC24,SOX11,KDM3A,TEX2,SRPK2,COLGALT2,SSTR1,LARP4,SS18,MAPK8IP3,SEPT8,STX1A,SYT1,CAMTA1,PDLIM2,SATB2,TRIM2,RPGRIP1L,WASHC4,WDR7,RALYL,FRYL,CSMD1,PRMT8,TSC1,CADM1,GORASP1,FLRT2,MICU3,TMEM237,WNK1,CA10,WIPF2,JMJD1C,VANGL2,ADAMTS10" MicroRNA hsa-miR-503:mirSVR_lowEffct hsa-miR-503:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.27E-95 2.40E-91 2.41E-94 2.22E-93 234 934 "RALGAPA1,NCKAP5,FAM43B,CSMD3,TMEM132B,GALNT13,SLC12A5,RNF150,ADRB2,AP2A1,C1QTNF1,LRRC7,USP35,SRPX,FAM135A,OGT,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APC,ALS2,TNRC6C,PPFIA3,IGDCC4,STK33,NUMB,DDX3Y,INSYN2B,CCDC181,ADAM23,TTLL9,BMPR1B,FUBP1,NAE1,JAZF1,CACNA1I,KALRN,CAST,RUNX1T1,USP2,MAGI1,NDST3,NRXN3,CLTC,HECTD1,BTF3L4,TBPL1,AHCTF1,CSF2RA,SNPH,ARHGAP24,PHF19,INTS1,DCC,ARMCX2,PLEKHM1,RABGAP1L,TMCC2,EXOG,HS3ST2,NYAP1,USP3,DYNC1I1,CDON,DNM2,DMTF1,DRD1,DYRK1A,DNM1L,ANKRD46,SGK2,FRY,PHF20L1,SUGP2,EIF4G1,PLEKHA1,ING4,ENO2,ANKRD13B,CEP85L,ARMCX1,TAOK3,FER,BAIAP2,PRKAG2,MEX3B,CAP2,IP6K2,RGPD5,SEMA4D,WDR83,NPTN,HHIPL1,DOT1L,GABRB3,ARPP21,SALL3,ERAP1,DNER,USP19,RUNDC3A,BRD8,RAB30,TOX3,TNRC6A,GNAL,FERMT2,STMN2,RAPGEF1,GRM2,WIF1,VSIG4,SYNPO,NKD1,NIM1K,C2CD4C,SLC35G1,KCNK2,KIF2A,KIF5A,KLC1,L1CAM,LIMS1,PACRG,MAN2A2,AQP11,TM6SF1,LRP1B,MOV10,NCAM1,NEUROD1,NF1,LRIT2,NUCB2,GPR88,OMG,PAK3,DPY19L2P2,PCMT1,PDE1B,GNG2,ANLN,KCTD15,JAKMIP1,PLXNB3,PURG,PMP22,SCHIP1,NXPH1,PPP3CB,RASGEF1B,MAPK3,SLC26A11,RELN,KLK6,CNNM2,WBP1L,MTMR10,PTHLH,PTPRD,PTPRN,TMEM255A,RAD52,RALGDS,FAT4,ZYG11B,RET,RFX4,ARHGEF10L,ZFHX4,GSTCD,FBXW7,KIAA0895L,SYNDIG1,SALL1,ATXN2,SCN8A,PRCD,SCAF8,SGK1,ITSN1,FRMPD1,KIF16B,CPEB3,NTNG1,CHD9,DZIP1,WDR37,ZNF365,FAM81A,SLC2A5,BTBD3,SLC20A2,IFT122,MBD5,MYO16,SON,SOX3,LHPP,PBLD,CAMTA2,MPRIP,ADHFE1,KANK1,STXBP1,FAM168A,VAMP1,SYPL1,SYT4,C12orf76,MTCL1,CAMTA1,AGTPBP1,MGRN1,SYNE1,PCDHA5,CRB1,LEFTY2,NR2E1,TPM2,ELP5,BCL2L13,NSD2,ZFP41,STOX2,SCG2,SEMA3B,PLSCR4,RTN4,CASC15,MSRB3,FXR1,SLC4A10,JPH3" MicroRNA hsa-miR-33a:mirSVR_highEffct hsa-miR-33a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.29E-95 2.41E-91 2.42E-94 2.23E-93 241 990 "ABHD6,SLC25A25,FMNL2,SLC12A5,BEND6,SORCS2,CC2D2A,ALCAM,UNC79,AMPH,CDC42BPA,DPP10,SEMA7A,USP28,PHF12,MAGEE2,TNRC6C,TMEM263,SPTBN4,ZFYVE28,ASCL1,ZNF583,SLC2A11,B3GALT2,BACH1,ADGRB3,CDK5R1,CACNA1B,THSD7A,KALRN,PTBP2,LDB2,USP6,AIFM1,LGI1,CHN2,CLCN3,QKI,MAP4K4,IQCK,ARMC8,AKAP6,AKAP12,CS,RGS6,SEC24C,MICAL2,VCAN,SOCS5,SLITRK5,DZIP3,PHF14,NRSN1,ST18,HDAC9,KATNAL2,ZFYVE16,DGKB,ZEB2,MYEF2,PLPPR4,SPOCK3,WDR20,RAB39B,ABI1,RCAN1,ARRDC4,DTNA,GOLT1B,E2F5,AASDH,EBF1,EDNRB,FCF1,SEMA3D,RBM12,EGFR,CALCRL,EN2,VPS13B,CLVS1,ABCA8,RPS6KC1,FER,OLFM1,FGF14,SMC2,ATP6V1H,KHDRBS3,CELF1,DKK3,HBS1L,SALL3,ERAP1,LRRC37A6P,MYOZ2,MSTN,GGTA1P,HTATSF1,GPD2,STON1,RAPGEF4,GRIK2,PRDM5,GRM7,ZNF496,LINC01551,ADAMTS6,MAP4K5,WIF1,RASSF8,HAS2,ZHX1,LINC01102,BACH2,HMGCR,HNMT,C9orf129,ZDHHC15,METTL21A,KCNA4,KCND2,KCNJ3,LIG4,LSS,MARK1,MATN3,MBNL1,MEIS2,POC1B,MMP16,ERICH3,MSR1,CTNNA3,MYO9A,NAP1L2,NAP1L3,NCAM1,NDUFA5,OTOGL,CNOT4,NPY,NPR2,OCRL,GPR88,GPR137C,PDE3B,PDE4D,ENPP2,GDAP1L1,NOMO2,PLIN1,PCDH18,PDZRN4,TRHDE,ING3,SPATA6,SH3KBP1,PPM1B,PPP3CA,PPP3CB,PROX1,MASP1,MDGA2,CNTLN,PTHLH,PXK,TMEM260,PTPN13,PTPRB,PTPRZ1,TTC13,ZNF615,MARCH1,RADX,ZDHHC14,SLC6A15,RGS12,SETD5,CARF,RPE,NEK11,FBXW7,CCDC112,TRAPPC13,SCN8A,LINC00461,SH3GL2,CPEB3,SLITRK3,ZNF365,SLC1A6,FAM81A,WDR47,SLC12A2,SLC14A1,SLCO1A2,SORCS3,SNRPN,ENKUR,MYCBP2,KIF1B,IQSEC2,COLGALT2,ZNF302,SAMSN1,SYT11,VPS13A,AGTPBP1,TBX15,DMXL2,SATB2,ZEB1,WASHC4,WDR7,RALYL,TEK,ZFPM2,CRB1,ITGB3BP,CSMD1,TPM3,KCNE5,CADM1,UGT8,TBC1D15,XRCC4,MICU3,TRIM9,FMN2,LAMP5,EMSY,PRDM2,PRTFDC1,NAV3,WNK2,SLC17A6,RGS7BP,GOPC,FAM13C,SLC4A10" MicroRNA hsa-miR-96:mirSVR_highEffct hsa-miR-96:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.31E-95 2.98E-91 2.99E-94 2.76E-93 233 927 "ABAT,ASPHD1,KDM5D,XKR4,KLHL32,ADCY6,ADD3,SLC12A5,KIDINS220,SLC24A4,KIAA1324,C1QTNF3,LRRC7,ABCD2,ALK,AMPD3,LRCH2,FGD2,C6orf89,UPRT,VAT1L,STK33,BRINP2,DPY19L3,ADGRB3,MIR9-3HG,DST,ARHGEF7,MTMR2,JAZF1,CACNA1E,CACNB4,THSD7A,LDB2,CCKBR,SEPT7,LGI1,MAGI1,TIGD7,CACNA2D2,CHM,NDST3,CLTC,LY86,NIPBL,TMEM155,CNN3,COL9A1,MYRIP,LRIG1,ERC2,APPL1,CTNND1,ECE2,HDAC9,ARHGAP24,FRMPD4,TM9SF4,DGKG,C8orf34,ZEB2,HP1BP3,ZC3H11A,PLPPR4,AK5,DLG2,DSCAM,GNE,E2F5,EDNRA,FAM13A,PHF20L1,EGR3,LPAR6,EIF4G2,PLEKHA1,CALCRL,GPHN,SRRM1,ZNF585B,FDFT1,FHL1,CAP2,FOXF2,NOP56,SMC2,FAM49B,ST6GALNAC3,NSG1,FYN,GABRG2,GAD2,BRPF3,B4GALNT1,NCKAP1,GAP43,DISC1,KIAA1841,SPIN1,GLS,PCDH11X,ZNF782,GPM6A,GPM6B,LILRA1,GPR12,GPR22,RAPGEF4,GRIA1,GRID1,RFFL,GRM7,KAT7,RASSF8,HAS2,ZHX1,ELOVL5,OPALIN,HSP90AA1,C2orf72,DOCK7,NME9,KCNK2,KTN1,ARHGAP12,TM6SF1,MITF,WDR49,MRPL42,TAGLN3,LAYN,MYO6,HNRNPM,NF1,NOVA1,DNHD1,GPR137C,SNTG1,PCDH9,PCSK1,PCSK5,PDE1A,PFKFB3,PIK3C2A,ANLN,FAM216A,PDZRN4,MAPKAP1,LRP12,SCHIP1,PRRX1,EPB41L4B,SH3KBP1,MED1,CRLS1,PPP2R5E,PTPRB,CEP97,RASGRF2,BSDC1,ZMAT4,RIC8B,ZFHX4,BAALC,MCMBP,FAM19A1,SOX6,TRIM46,MRAS,SUPT20H,SH3GL3,MAGI3,FHOD3,SYBU,CTXN2,DZIP1,NUBPL,FAM81A,PPP4R3A,BTBD3,SLC6A9,RAB3GAP1,RCOR3,IFT122,RIMS1,MYO16,SOX5,SOX10,KDM4C,KIF1B,CLASP2,POGZ,EPB41L3,LRRC4,SS18,TTBK2,ADHFE1,AJAP1,KLHL7,JMJD6,ZFR2,TAC1,FBXW11,TBL1X,TBX15,TCF7L2,ZEB1,PCDHB6,SIK3,TF,FAM200B,DICER1,TIMP4,TPM1,RUNDC3B,ZMYND8,DCBLD1,ANO5,RPL7L1,UBE3A,SLAIN1,VLDLR,ZIC3,TRIM9,TMEM198,ZFAND5,NAV3,LINC00632,PDSS2,JMJD1C,NETO2,SLC4A10,GAN" MicroRNA hsa-miR-1225-3p:mirSVR_lowEffct hsa-miR-1225-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.51E-95 3.66E-91 3.67E-94 3.38E-93 261 1158 "DPF1,SERPINA3,ABAT,DGCR6,KDM5D,FAM43B,GPRIN1,SLC25A25,NDRG2,ADARB2,GALNT16,ADCY6,KIDINS220,AP1B1,OSBPL1A,TBC1D14,KIAA1324,DISP3,CC2D2A,AK2,FGD2,MYH7B,CNIH2,PKP4,BCAS1,APP,KIAA1614,SEMA4G,MADD,ARHGAP5,ASCL1,ASPH,NUMB,RIPK1,ADAM23,TTLL9,CFLAR,BMP7,LURAP1,CABP7,KALRN,NGB,SLC25A14,CBS,CD86,CDC25B,CDH2,CRLF1,NUMBL,PLEKHB1,DLGAP3,EPS15L1,CPNE6,NRXN2,CLU,TJP2,FADS2,TMEM184B,SLC25A27,LETMD1,COL11A2,IFFO1,COX4I1,ZNF385A,SH2B1,TENM4,CST3,RIMS2,PPP6R2,GPSM1,ST18,DCAF8,PHF19,PHYHIP,DBI,AIF1L,GIT2,ELMSAN1,ZBTB24,COPS7A,C2CD2L,RHOBTB1,SV2A,DLG2,DMPK,DNM2,DUSP9,E2F5,AASDH,CACNG7,RASA4,ELAVL4,ELN,PAN3,EPB41,LRRC17,EFS,CEP85L,EZH1,SCML2,FGF14,FGFR1,ATP13A4,SYT3,POMT1,APOPT1,UFM1,STAMBP,ERGIC3,CELF1,BRSK1,TVP23A,GABRB3,KIAA1841,ALDH1L1,SULT1C4,GFER,GFRA2,CSDC2,MSL3,STARD3,LILRB4,GRIA1,ADAMTS13,PRDM5,LINC00839,PTPN5,UBE2QL1,ELOVL5,HMGCL,ZDHHC15,C2orf72,TJAP1,HES5,IL11RA,INPP5B,ITPKB,KCNC1,KCND1,KCNJ9,KCNK1,CREG2,KLRC2,A1BG-AS1,STMN1,MAP4,ADAM11,PTOV1,MT3,MTR,LYRM9,MYO7A,NHLH1,NOVA2,NPTX1,PCBP3,NTRK2,NTRK3,TBC1D25,OPHN1,PCSK2,OLA1,ZDHHC8,CAMKV,ZNF655,FTO,C11orf49,TNPO2,TMEM235,PPP1R1A,PTPA,NKAIN4,PPP5C,PRKAB2,PRKACB,PRKCG,SLC26A11,DCHS2,RELN,NDUFS7,GON4L,ACSM5,TUG1,CEP97,BSDC1,RGS12,SEC61A2,KLHDC8A,GSTCD,YY1AP1,PAQR6,KCNIP3,RTKN,YJEFN3,KCNIP2,STX1B,CSRNP3,LRRTM4,SLC30A10,TRIM46,GALNT10,ASRGL1,NTNG1,HKDC1,SLC2A5,LRRC55,SLC6A11,YPEL4,RAB3GAP1,SLC8A3,SLC9A5,SCMH1,ABTB1,TTC17,FAM219A,MYT1L,SOX5,SOX10,SP2,ZSWIM8,CLUAP1,IZUMO4,KDM4C,TEX2,SPTAN1,IQSEC2,NPAS3,RAP1GAP2,NFASC,MESP1,NKAIN2,SSPO,MAPK8IP3,SEPT8,NSFL1C,TACC1,ANO4,SATB2,PHF24,NSD1,ARL10,MTMR14,TK2,TLR4,DAAM2,TNS1,PIK3R5,WBP2,AMACR,NUTM2A,VAV1,LGI4,CFAP298,ZBTB14,CRB2,PRTFDC1,NT5M,GDPD5,ADAMTS9,DOCK8,GJC2" MicroRNA hsa-miR-3138:mirSVR_highEffct hsa-miR-3138:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.83E-95 4.40E-91 4.40E-94 4.06E-93 230 905 "ARID1A,CCDC85A,SNX32,ADGRF5,C1QTNF3,SEMA6A,PCDH10,SYT13,DPP10,APP,PCDHGB4,ZNF583,SYNJ1,DDR1,CALM1,KALRN,CAST,CDC25B,CDC42,CDH8,CIART,CHM,CHN2,CHRM1,CASC2,ZFYVE9,NRXN2,FAM189A2,NIPBL,TMEM155,FHL5,AKAP6,LETMD1,SLC4A8,RNF14,CSF1R,RGS6,FEZ1,UBXN2A,CFAP61,ZSCAN23,EDRF1,GPRASP1,ZFYVE16,TM9SF4,TMEM170A,ZBTB24,EXOG,USP3,DTNA,ABCC5,GOLT1B,FAM135B,RBM12,YAF2,EGFR,AASS,C3orf18,PAN3,ENO2,EPB41,GPHN,SRRM1,DENND4A,SIRPB1,GMPR2,NRN1,ZNF461,DLC1,CEP78,TOMM40L,KIAA1109,SCARA3,NELFCD,SMC2,SPECC1,CGREF1,PNMA2,MEGF10,GABRB1,GAD2,DISC1,TXNL4A,GLI2,RAB30,GLUL,PCDH11X,INSM2,DCLK2,STON1,CECR2,KIF3A,KAT7,GUCY1A2,GUCY1B1,SHISA6,SMAP1,USP54,NME9,KCNA2,KCNK1,KIT,SYTL4,MBD1,MOBP,CTNNA3,RSPO2,P2RY13,NDUFA5,NELL2,NF1,SLCO1C1,OPA1,OPHN1,LOC100128398,CLDN11,PAK3,PBX1,PCDHGC3,PDE3B,PDE4A,PDGFRA,HERC2P3,ZFYVE21,PPM1B,PPP2R2C,PPP2R5E,PPP3CA,KANSL1,PKN2,MAPK10,GRAMD1C,GDPD1,DCHS2,MASP1,SYTL2,MDGA2,PTHLH,TMEM260,TMEM255A,RAD51D,ZNF493,RASGRF2,FEZF2,ERI2,RGR,RGS12,ZFHX4,ZNF532,SETD5,TMEM206,SNX22,ZNF354C,ASIC4,TRIM46,NLGN4Y,SH3GL2,PPM1E,WDR37,ZNF365,PPP4R3A,BTBD3,ZNF430,SLC12A2,SORCS3,MBD5,PALLD,LMO3,ATP10B,CLASP2,SS18,MPRIP,PRRC2C,NUDT10,POPDC3,TACR1,MTCL1,TBL1X,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ARHGAP9,CYB561A3,CRB1,AP4E1,TIAM1,TIE1,RIMBP2,TPM1,C9orf85,SMUG1,TRIO,AMACR,TRO,FNDC5,TSC1,TTTY15,HSPBP1,ZNF610,FLRT2,VLDLR,BEST1,WNT7A,ZFP37,ZNF711,AGMO,FSTL5,MAP3K12,LMAN2L,TMEM178A,KCNAB1,CAB39L,FZD3,PAK5,ZNF248,RNF170,FRMD6,NETO1,LAS1L" MicroRNA hsa-miR-208a:mirSVR_lowEffct hsa-miR-208a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 9.01E-95 5.06E-91 5.07E-94 4.67E-93 221 836 "RALGAPA1,KCNH8,CLK4,NCKAP5,KDM5D,KLHL32,OSBPL1A,HFM1,FAM135A,ZFAT,LRCH2,PPFIA2,APC,TNRC6C,ASCL1,ASPA,ATP1A2,ATP2A2,ATP2B1,ADGRB2,DST,MTMR2,PRMT9,C5,IL33,PTBP2,VSTM2A,ISPD,MAP7,KRIT1,CD38,CDH2,CASC2,NDST3,KMT2C,NRXN3,HECTD1,SLC4A8,ABI3BP,AHCTF1,ACBD5,ZNF521,NRG2,RBM39,RNF14,ANKRD44,RGS6,SOCS5,HDAC9,ARHGAP32,ARHGAP24,ZFYVE16,YTHDC1,ZEB2,MYEF2,HP1BP3,DMD,USP3,DMTF1,ABI1,E2F5,EBF1,WDPCP,FSD1L,PHF20L1,EIF4G2,TENM1,ELAVL2,PLEKHA1,RGS17,IGSF6,RRAGB,F3,ST3GAL6,TESK2,FGF13,NELFCD,STAU2,ZNF512,OGA,GABRA2,B4GALNT1,KIAA1841,MYOZ2,MSTN,GDF9,GLYR1,PCDH11X,PRUNE2,CACFD1,PRDM5,TNFAIP8L3,MIER3,HLF,HMGB1,IGFBPL1,SHISA6,IL6R,BRINP3,LRRTM1,KCNC2,KCNN3,IPO5,LIG4,MATN2,SRSF12,CD200,NRBP2,CTNNA3,NDUFA5,NEFH,NELL2,NF1,NOVA1,OCRL,OMG,PDE1A,PDE2A,XRN1,GPSM2,SLC25A23,MAPKAP1,RC3H2,ING3,NXPH1,SH3KBP1,DRAM2,PPP3CA,PPP3CB,RASGEF1B,MAPK8,MAPK10,MTMR10,PTPRG,PTPRO,PPP2R3C,CEP97,SH3TC2,FAT4,ZCWPW1,RADX,RFX3,RNASEL,ROBO1,TMEM100,ATP8B4,MEG3,RMI1,SALL1,SATB1,FAM19A1,FNIP1,SEC14L1,HSPA4L,KIF21A,SH3GL2,MAGI3,AMBRA1,FNDC3A,SYBU,PAAF1,ZNF365,SEPHS1,ELMO2,ATF7IP,SPHKAP,SMARCC2,DMRTC1,SMARCE1,RIMS1,LMBRD1,UNC80,DOP1A,SON,SOX5,KIF1B,SRPK2,POGZ,RGL1,DIP2A,KANK1,FGD4,PRRC2C,VPS13A,DNAJC9,KAZN,FAM208A,TCF12,SYNE1,PHF24,PCDHB3,FRYL,ITGB3BP,SLC44A1,GALNT17,DDHD1,TMOD1,TP53BP1,RBFOX2,PPIL6,RUSC1,PRR18,DNAJC12,BCL2L13,ZNF540,REEP1,ANKS1B,MEIS3,INTS3,CA10,SLC30A4,EMSY,CADM2,SLC38A1,PCDH15,SLC17A6,AMN1,FZD3,FBXO36,TRAM2-AS1,SLC39A12" MicroRNA hsa-miR-1208:mirSVR_highEffct hsa-miR-1208:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-94 6.69E-91 6.69E-94 6.16E-93 249 1060 "RALGAPA1,KCNH8,SYN3,CLK4,ABHD6,CSMD3,ADAR,ADCY2,SLITRK1,ADD2,ADD3,SORCS1,PWWP2A,PTCHD1,BEND6,SLC44A5,AP2A2,ALCAM,LTBP4,FAM135A,OGT,ANK3,DGKZ,ALS2,SHTN1,MIER1,CAPRIN2,ASTN1,CCDC181,N4BP2L1,DPY19L3,SEC11C,PROM1,FUBP1,CARS,CCNH,CDC27,CDH2,CDH18,CHN1,CHN2,CASC2,B4GALT6,IGFBP7-AS1,TPP1,C4orf33,HECTD1,MAP4K4,ARHGEF6,ARMC8,AKAP6,BTF3L4,SMARCAL1,RTTN,CP,FAM171B,PREPL,ATRNL1,SIPA1L1,SOCS5,ERC2,NRSN1,USP6NL,ZNF337,C2CD2L,RHOBTB1,SPOCK3,EXOG,CPEB2,CASP8AP2,DPP6,DPYSL2,DRD1,ABI1,DTNA,FAM78B,MAMLD1,DYRK1A,ABCC5,USH1C,HIPK3,OPTN,RBM12,EGFR,ENO2,EPB41L1,EPHA5,EPHB1,ADGRV1,ARMCX1,ZNF461,ZIC4,ST3GAL6,CEP78,FDFT1,FGF13,FGFR1,FHL1,NOP56,JKAMP,NBEA,DACH2,ST6GALNAC3,GABRG2,BRPF3,ZNF274,GAP43,SULT1C4,GK,GLI2,GLS,TOX3,GPM6B,GPR22,CNTRL,GRIA4,GRIK4,KIF3A,SOX21,GUCY1B1,RASSF8,PTGDR2,FRMD3,HNF4G,HNMT,IGFBPL1,ZNF491,FAAP20,USP54,DIPK1A,INPP5B,ZNF385B,KCND2,LAMP2,PAXBP1,FGFBP3,MAT2A,LDLRAD3,TM6SF1,MEIS1,XRRA1,NAP1L3,NFE2L2,CLDN11,GPR137C,SNTG1,PDCD2,ZDHHC8,SERPINI1,ANLN,STRN3,ING3,PPM1B,PPP2R5C,RELN,CNTLN,PTCH1,PTHLH,ELOVL2,PPP2R3C,SH3TC2,RASGRF2,RADX,SLC6A15,RFX4,TTLL7,ROBO2,BAALC,CNTNAP3,NCBP3,SEMA6D,SATB1,ATXN7,TRIM46,ARX,SHMT2,FNDC3A,BTBD3,RUFY2,SLC8A3,CCDC88A,BTBD7,CPEB4,RCOR3,LIMCH1,SNAP25,MBD5,SON,MYT1L,ZC3H13,SRPK2,ATP10B,ITPRID2,ZC4H2,STAU1,ZSCAN29,RGL1,DIP2A,NECAB1,SYNE2,VAMP1,VPS13A,PLCB1,COBL,CAMSAP2,ADGRL3,CUX2,ZEB1,WASHC4,SYNE1,ZMAT3,MTMR14,TLL2,TLR4,ERCC6L2,HEY2,TMPO,RIMBP2,C5orf64,RGMB,ANKRD20A2,RFTN2,SLC35A4,UBE3A,GORASP1,FLRT1,FAM181B,WIPF1,WRN,LGI4,ZIC3,ZNF19,MKRN3,LYPD6,TCEAL7,ZBTB38,ANKS1B,MFF,CADM2,NT5M,LINC02210,NAV3,PPP1R3F,FAM13C,ST7,PHTF2,FRMD6,ST8SIA2,ZNF30" MicroRNA hsa-miR-142-5p:PITA hsa-miR-142-5p:PITA_TOP PITA 1.54E-94 8.64E-91 8.63E-94 7.95E-93 208 741 "RALGAPA1,CLK4,CCDC85A,USP31,GPR158,ALCAM,FAM135A,CDC42BPA,GAS7,ALS2,ASCL1,CAPRIN2,ZBTB10,SLC4A4,ATP2B1,ADGRB3,SYNJ1,SGCE,CAMK2A,SPAG9,LDB2,CCNH,SEPT7,REPS2,CCPG1,CHGA,NRXN3,CLCN3,TJP2,QKI,MAP4K4,ARMC8,SLC25A27,AKAP5,SLC4A7,SLC35F1,CRY2,TENM4,CSNK1G3,APPL1,FAM131B,HDAC4,TOX,SPOCK2,C8orf34,MAGI2,RHOBTB1,SACS,SPOCK3,FAM107B,DLG2,DLG3,NR1D2,CPEB2,DRD1,ABI1,RBM12,KMT5B,ABI2,EGR3,ELAVL2,ELAVL4,CALCRL,ERBB4,ETV1,MED12L,FGF13,NBEA,SORBS1,FAM49B,ST6GALNAC3,PHYHIPL,CHL1,BRPF3,NCKAP1,FAXC,GK,GLS,LUZP2,GPR37,CECR2,RAPGEF1,CIT,RNF165,ADAMTS6,BACH2,MIER3,CELF5,IGF1,C5orf24,IL6ST,ITGAV,KCNJ3,KIT,IPO5,L1CAM,LIFR,SFXN5,NCOA7,MBD1,LRP1B,MEIS1,MEIS2,KITLG,MKLN1,MYCN,NEXMIF,NFE2L2,NTRK3,PDE4D,PDGFRA,PFKP,PIK3C2A,PIK3CD,RETREG1,HMGCLL1,LRP12,SCHIP1,RETREG2,FAT3,MINDY2,PPP3CA,PKN2,MTMR10,PTPRD,CEP97,TMEM255A,ATG16L1,FAM184A,RBBP8,REV3L,FIGN,RIC8B,PBRM1,ZFHX4,ALG9,ROBO1,TMEM100,BAALC,ST6GALNAC6,RTN1,RYR3,RMI1,ATXN1,SCN2A,SCN3A,FAM19A1,FNIP1,SUPT20H,HSPA4L,CPEB3,SHC4,CHD9,FNDC3A,CCDC92,FAM81A,BTBD3,SLC11A1,CPEB4,RIMS1,MBD5,SOX1,MYT1L,SOX5,SOX11,SP2,FCHO1,STAU1,RGL1,SEPT3,FAM168A,FGD4,ANKRD28,ATP11A,TACC1,ANKRD12,CAMTA1,CAMSAP2,ADGRL3,FBXW11,TCF4,TRIM2,TCF12,PSD3,ARHGEF12,PUM2,SIRT1,ZFPM2,SLC44A1,TIAM1,DDHD1,TMOD1,TNS1,STXBP4,TRPC1,CADM1,FAM155A,SLAIN1,ZBTB38,RGMA,PRDM8,SLC17A7,PLSCR4,GOPC,CERS6,JMJD1C,NETO2,ST8SIA2" MicroRNA hsa-miR-4312:mirSVR_lowEffct hsa-miR-4312:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-94 1.04E-90 1.03E-93 9.52E-93 259 1146 "CPNE2,KCNH8,ACADM,ACTN2,KDM5D,CSMD2,SORCS1,GRAMD1B,ESYT2,HECW2,KIAA1324,OSBPL6,LRRC7,SEMA6A,ARHGAP20,ANK1,EP400,APOC1,PPFIA3,ARRB2,ASGR1,PCDHGB4,EIF4G3,ATP2B1,ATP6V0A1,ADAM23,AZGP1,BCHE,NAE1,IL33,CACNA1E,TRIM41,VXN,VSTM2A,CAST,CARS,DGKI,CDC42,CDH8,NUMBL,KMT2C,ZFYVE9,TPP1,STOML1,TJP2,SRP14-AS1,AKAP6,WHRN,SLC25A27,LETMD1,TOGARAM2,HS3ST5,SLC35F1,C2CD2,TRIM69,TENM4,SEC24C,APPL1,CMTM5,PPP6R2,RUBCN,KIAA0408,PHF19,RASSF2,DGKG,KIAA0319,NTM,CDON,DPH1,PDCD6IP,ARRDC4,EDNRA,ANKRD46,RBM12,PHF20L1,SUGP2,KMT5B,GOLGA7,ELAVL4,EML1,VPS13B,ANKRD13B,ERCC2,DENND4A,CDHR1,RRAGB,EZH1,TUBB4A,RACK1,FCGR1A,TOMM40L,FKTN,ZSCAN30,FECH,SEC24B,FGF13,FHL1,SCARA3,HPCAL4,FOXF2,SYNCRIP,FLT1,NOP56,C2orf88,EFCAB2,SORBS1,PDLIM5,NPTN,STAU2,DOT1L,HRASLS5,ATP8A2,MSTN,GNG3,TMEM121B,STMN2,PLPP7,PRDM5,CIT,HAS2,DDX19B,HLF,HNMT,IDH3B,DISP2,INPP5B,KCNA6,KCNH2,KCNJ16,A1BG-AS1,KLC1,KTN1,LAMP2,PACRG,MATN3,MBNL1,CHIC1,XRRA1,ADAM22,PTOV1,SCG3,MTTP,MXI1,MYH6,NEXMIF,NF1,ALDH1L2,NTRK3,NUCB2,P2RX7,P2RY1,PAK3,CNTN3,PCDHGC3,PDE1A,SERPINI1,HMGCLL1,PMP2,DRAM2,PPP2R5C,PTHLH,ELOVL2,ZIK1,FAM120C,PTX3,TMEM255A,SH3TC2,SLC25A41,UBR7,RGS4,ALG9,ZC3H14,PRR5L,EMID1,RMI1,SBF1,GALNT10,SH3BGR,AMBRA1,WDR37,SLC8A1,RAB3GAP1,ARHGEF40,SLC15A2,SLC20A2,SLCO1A2,CXXC4,SMARCD3,KIF13A,CABCOCO1,UNC80,PDZD2,BDP1,CLUAP1,KDM4C,UNC5B,DBNDD2,ZBTB43,PBLD,ZSCAN29,NSFL1C,SYT11,SYNE2,VPS13A,SEMA4A,TMEM136,TCF7L2,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,DICER1,TMEM121,AP4E1,ERCC6L2,KCTD2,R3HDM1,TPD52,NPL,PRMT8,TRO,FNDC5,HSPBP1,PITPNB,BEST1,PORCN,CLDND1,GUSBP1,PCDH20,ZNF28,LYPD6,EML6,DNALI1,MDH1B,PCDH15,WNK3,GOPC,FZD3,HNRNPA3,SSPN" MicroRNA hsa-miR-1273d:mirSVR_highEffct hsa-miR-1273d:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-94 2.24E-90 2.23E-93 2.06E-92 228 896 "CLK4,GALNT13,ADD3,BEND6,ZNF608,MTUS1,OSBPL8,C1QTNF3,LRRC7,UNC79,ALK,PITPNM2,USP28,SUGT1P4-STRA6LP-CCDC180,GPAM,ALS2,APP,SPTBN4,ARNTL,RGS20,LINC00173,ASCL1,ATP1B3,RIPK1,DST,FUBP1,NAE1,JAZF1,AP1M1,KALRN,SLC25A14,VXN,CLDN10,CCNH,LRBA,CDC42,MAGI1,TIGD7,CLGN,SRSF11,MS4A7,SYNPR,CNOT8,KMT2C,RAB33A,NRXN3,MAP4K4,FHL5,AKAP6,WHRN,SLC4A8,ACBD5,TENM4,SUSD5,ATRNL1,PITPNM3,ST18,CCDC144A,DCAF8,LONRF1,DGKB,GIT2,ZEB2,TIAM2,DDX46,RHOBTB1,SMG7,DYNC1I1,CPEB2,DPP6,DRD1,DTNA,DTNB,ABCC5,ABCC9,AASDH,EDN1,FRY,AASS,COPS4,ELAVL2,EIF1,EMX2,EN2,DENND4A,SPEG,FCGR1A,GORAB,FER,FHL1,NBEA,ARFGAP2,ZNF512,OGA,STAG2,JPH4,ARFIP1,GGTA1P,GLS,ZNF638,GNAS,RAPGEF4,GRID1,MAP4K5,HAS2,PADI2,ARHGAP36,FAAP20,ZIC5,IGSF1,SLC35G1,KCNH2,KCNJ11,LAMP2,INSYN2,VWA5A,SMAD1,MARK1,LDLRAD3,MEF2C,KITLG,POC1B,NAP1L1,NF1,NKX2-2,SLC11A2,NRCAM,HCN1,ODF2,CNTN3,PDE3B,SLC10A4,GPR85,NLGN3,ZNF655,PLCB2,ST8SIA5,PLCL1,HMGCLL1,MAPKAP1,SCHIP1,ING3,PPM1B,TATDN3,CRLS1,PPP2R5C,PPP3CA,RASGEF1B,HYDIN,CNTLN,ZSCAN32,OCIAD1,RAP1GDS1,ZNF532,ROBO1,ACER3,STK32B,LRRK2,AMER2,MIR124-2HG,SEMA6D,SCN2A,SCN3A,SCP2,SGK1,ZFP30,CHD9,FNDC3A,FHOD3,FAM214B,SLC8A1,NAPB,SORCS3,SON,MYT1L,TNIK,HECW1,KDM4C,ZBTB43,RBM26,NPAS3,PBLD,ITPRID2,EPB41L3,NKAIN2,KANK1,PRRC2C,PLCB1,DDHD2,CAMSAP2,TMEM136,ANO4,TCF4,TCF7L2,TRIM2,GPRIN3,TEX15,HEY1,TMPO,TPD52,NEIL2,AMACR,STXBP4,TRPC3,TSC1,UCHL1,SLAIN1,VAV2,VLDLR,CLDND1,ZNF540,PLPP4,ZNF184,SLC30A4,PRDM2,LRP8,RNF103,TUBA1A,FAM47E,SLC17A6,PDSS2,AMN1,ZNF248,FXR1,FRMD6,RNF146,CBLN2,GAN" MicroRNA hsa-miR-30c-1*:mirSVR_highEffct hsa-miR-30c-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.14E-94 2.32E-90 2.31E-93 2.13E-92 261 1167 "NBAT1,NDRG2,SLITRK1,ADD2,PWWP2A,ADORA3,GPR158,KCTD16,WDR35,AK2,C1QTNF3,LRRC7,ALCAM,MARCH4,PCDH10,BIN1,LRFN1,CDC42BPA,TNRC6C,SHTN1,MIER1,SEMA4G,ASPH,DDX3Y,NOL4,ADAM15,SEC11C,ARHGEF7,JAZF1,OSGIN2,CACNB2,VXN,SYT6,RUNX1T1,LDB2,TMEM257,CDC27,CDH10,LGI1,CHM,CHN2,CASC2,TAOK2,KIAA1549L,TMEM155,IQCK,FAM149A,AKAP6,BTF3L4,COL9A3,CHD1L,CREM,HAPLN1,RGS6,LRRC3B,CTNND1,CTNND2,RUBCN,MYADM,KATNAL2,DCAF8,FRMPD4,MAML1,ZEB2,ZC3H11A,RHOBTB1,SV2A,AK5,GRIN3A,SLC29A4,SHANK1,DTNA,MAMLD1,DYRK1A,ABCC5,DNM1L,E2F6,AASDH,WDPCP,HIPK3,SIDT2,GPR61,SUGP2,EGFR,MBNL2,KCTD3,EPB41,EPHA5,EPHB1,RTN3,RACK1,PPP1R1B,KIAA1109,POLR1B,SPSB4,FGF13,FHL1,CAP2,NELFCD,PDLIM5,USP21,GABBR1,AHCYL1,ERAP1,C15orf41,DISC1,SRRM4,TUBGCP4,ADAM28,GGT7,MALT1,GLDC,LOXL3,WDFY3-AS2,PRUNE2,MCHR1,ATP2B1-AS1,PLCD4,NR3C1,KIF3A,RABL2A,SOX21,RNFT2,ADAMTS6,FRMD5,ARHGAP36,MIER3,AGBL5,HNF4G,LRRCC1,LRRTM3,KCNJ3,KCNK2,VWA5A,MAG,MOBP,MT1M,FXYD6,P2RY13,NASP,NEFM,NF1,SLCO1C1,NOS1,TBC1D25,IGSF11,OPA1,DPY19L2P2,PCSK2,GNG2,NLGN3,PLCB2,MTRF1L,PURG,PPP2R5C,CEP41,RELN,MDGA2,CNTLN,TMEM260,PTPRH,PTPRO,RAB5B,ZCWPW1,ZNF493,ARID4A,DBX2,GTDC1,RFX4,RNF220,TMLHE,EXD2,KIRREL1,KCNIP2,SCN3A,SCN8A,SGK1,ITSN1,KIF16B,CPEB3,FNDC3A,BCAN,NLGN1,PAAF1,SLC1A3,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,SCMH1,ATF7IP,SPHKAP,ZKSCAN3,SMARCC2,RIMS1,SNCA,CABCOCO1,DOP1A,ZSWIM8,ZNF423,SPTAN1,DDN,TAB2,ATP10B,CLASP2,ZC4H2,NKAIN2,STAU1,SEPT8,SULF2,SYNE2,SYP,TACR1,MTCL1,KLHL4,EHBP1,RPGRIP1L,WDR7,OBSL1,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,CYB561A3,CRB1,C18orf54,ITGB3BP,AKTIP,SLC44A1,NR2E1,TPM1,TPM3,NEIL2,TRPC1,PRR18,SGK3,TUBB1,UBE3A,FLRT2,PLEKHH2,KLC2,GUSBP1,ZIC1,ZNF19,SPIRE1,FTSJ1,MEIS3,HPS4,SLC17A7,MVB12B,UBE3B,ACTR3B,KLHDC1,NETO2,FAM198A" MicroRNA hsa-miR-656:PITA hsa-miR-656:PITA_TOP PITA 4.64E-94 2.61E-90 2.59E-93 2.39E-92 196 659 "NDRG3,FMNL2,AXIN2,HECW2,PCDH19,LRRC7,ARHGAP20,OGT,API5,USP37,AQP4,TMEFF1,DDX3Y,MTMR9,ADGRB3,BCHE,NRP2,JAZF1,CACNB2,KALRN,RUNX1T1,ZNF501,KRIT1,LRBA,SEPT7,MAGI1,CLGN,FOXN3,SOCS6,B4GALT6,NRXN3,KIAA1549L,NRXN1,TMEM184B,ARHGEF6,BTF3L4,GDA,CS,SOCS5,RIMS2,GAPVD1,HDAC4,DGKG,DCC,ZNF804A,C8orf34,COPS7A,MAGI2,RHOBTB1,FAM107B,DLG3,DMD,NYAP1,NR1D2,ABI1,RASGRP1,MBNL2,EGR3,OLIG2,RCAN2,ETV1,EYA1,ZIC4,SGIP1,ST6GALNAC3,TBR1,STAG2,GABRA5,CHL1,GABRB3,BRPF3,MSTN,GK,SPIN1,RAB30,GLRB,HTATSF1,LOXL3,RAPGEF4,WIF1,BACH2,HNF4G,NEGR1,HSP90AA1,IL6R,KCND2,CLVS2,KCNJ10,SMAD1,MAP2,MATN3,LRP1B,MEF2C,MGAT3,SCG3,HS6ST3,MYT1,NAP1L3,NCAM2,NF1,CNOT4,NOVA1,NPTX1,PCDH9,PCSK1,PCSK2,CDK18,GNG2,PIK3C2A,PIK3R1,CCSER2,XRN1,PMP22,RC3H2,PRRX1,MINDY2,SNRK,PTCH1,PTPRB,PTPRD,FAM120C,PLEKHB2,OXR1,RDX,RFX5,ROBO2,RORB,RPE,ZC3H14,WLS,RMI1,SEMA6D,ATXN2,SCN3A,FAM19A1,SOX6,SFPQ,NLGN4Y,ZFP30,KIF21A,PPM1E,CPEB3,FNDC3A,SLITRK3,CCDC88A,TET1,CPEB4,RIMS1,SNAP25,PALLD,FAM219A,PDZD2,SOX2,SOX11,ARHGAP26,RBM26,TAB2,CLASP2,POGZ,LARP4,LRRC4,SS18,SEPT8,PLCB1,SYT1,ANKRD28,TACC1,TBL1X,SATB2,RPGRIP1L,PSD3,SLC35G2,FRYL,TEK,HHIP,TLL2,ERCC6L2,TMOD1,TNR,TNS1,NR2C2,TRPC3,TRPS1,UBE2H,WNT7A,MICU3,CADM2,NAV3,CAB39L,SLC17A6,RGS7BP,PHTF2,CERS6,FRMD6,SOCS4,GAN" MicroRNA hsa-miR-3167:mirSVR_highEffct hsa-miR-3167:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.20E-94 2.92E-90 2.91E-93 2.68E-92 257 1134 "SERPINA3,ARID1A,XKR4,TMEM132B,AXIN2,SORCS1,NLGN4X,PCDH19,CC2D2A,TAOK1,SEMA6A,CARNS1,FAM135A,OGT,DPP10,ANK1,ANK2,ANK3,SUGT1P4-STRA6LP-CCDC180,PARG,APBA2,PHYHD1,LGR5,RGS20,ATP2B2,RNF182,ALDH7A1,ATP6V1G2,TTLL9,RGS9,NRP2,CFLAR,SCAPER,JAZF1,GYG2,SLC25A14,SYT6,CAST,USP6,TMEM257,DGKI,TIGD7,CHM,KIAA1549L,QKI,NIPBL,AHCTF1,RTTN,AKAP12,SLC32A1,SNCAIP,CSF1,FEZ1,ARHGEF10,GREB1,NRSN1,RIMS2,DCAF4,RUBCN,HDAC9,GAPVD1,DBN1,DNAJC6,PLEKHM1,MAGI2,WDR20,DYRK1A,DNM1L,GOLT1B,EBF1,EDN1,ANKRD46,PHF20L1,ELAVL2,EPB41,EPHB1,ANKRD13B,CEP85L,ZNF549,CDHR1,NRN1,F5,WAC,ZIC4,TOMM40L,FKTN,TESK2,CAP2,FOXM1,ANKFY1,USP16,TRIM16,NPTN,ST6GALNAC3,AP4B1,FYB1,GABRA2,GALNT15,GAD1,WASF3,TUBGCP4,TUBA8,SULT1C4,ARFIP1,SESN1,RUNDC3A,GK,GLYR1,GLRB,CBX1,GNAS,FERMT2,GPM6A,CCDC184,GPR34,CNTRL,GRIA4,GRM7,LINC01551,FICD,UBE2QL1,TNFAIP8L3,NEGR1,LIX1,OLFM3,KCNN3,KIFC3,KLC1,MAP4,MBNL1,MEF2C,MITF,ADAM22,MSRA,MTTP,NAP1L1,NAP1L3,NF1,VWA2,LRIT2,NTRK2,NUCB2,CLDN11,CNTN3,PAX6,PDYN,PLP1,PCDH18,PMP2,PMP22,SH3KBP1,DRAM2,MED1,PPP2R5E,PRKACB,HYDIN,SIDT1,MDGA2,CNTLN,ANKHD1,ZSCAN32,PTPRE,ZNF615,CEP97,SLC25A48,RALGDS,NWD1,RAP1GDS1,ZNF493,KCTD17,RIC8B,CARF,CCDC102B,TCP11L1,ABCA11P,RTN1,ZNF568,SCN8A,LINC00461,NLGN4Y,SHC4,HKDC1,MAGI3,NUBPL,WDR37,FAM81A,SLC2A5,RUFY2,ZNF430,SEPHS1,ATF7IP,INTS9,SMARCE1,SNRPN,PALLD,UNC80,KDM4B,SOX2,SOX5,EMC1,SPART,ZNF302,NKAIN2,SS18,NXT2,ADHFE1,SULF2,FGD4,PRRC2C,SYP,ANKRD28,SYT4,PJA1,DDHD2,AGTPBP1,EHBP1,ZFP90,CUX2,TCF12,PCDHB4,PCDHB3,NSD1,USP32P1,RNF175,SIK3,RNF216P1,ASXL3,TMPO,FAM124A,RIMBP2,C9orf85,ZNF384,RGMB,SYNPO2,TRPC3,TTC3,ZKSCAN5,FAM155A,UBE2H,DNAJC12,BCL2L13,ZNF781,ZNF711,ZNF708,MICU3,REEP1,EML6,EMSY,PRDM10,TRIM16L,EPM2A,FBXO36,ADAMTSL3,JMJD1C,TIGD6,KLHDC1,SOCS4" MicroRNA hsa-miR-30c-2*:mirSVR_highEffct hsa-miR-30c-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.64E-94 5.41E-90 5.38E-93 4.95E-92 255 1120 "NBAT1,SLITRK1,ADD2,PWWP2A,ADORA3,GPR158,KCTD16,WDR35,AK2,LRRC7,ALCAM,MARCH4,PCDH10,MRTFA,BIN1,LRFN1,CDC42BPA,TNRC6C,SHTN1,MIER1,SEMA4G,ASPH,DDX3Y,NOL4,ADAM15,SEC11C,ARHGEF7,JAZF1,OSGIN2,CACNB2,VXN,SYT6,RUNX1T1,LDB2,CD86,TMEM257,ARHGEF2,CDC27,CHM,CHN2,TAOK2,KIAA1549L,TMEM155,AKAP7,IQCK,FAM149A,AKAP6,BTF3L4,COL9A3,CHD1L,CREM,HAPLN1,LRRC3B,ERC2,CTNND1,CTNND2,MYADM,DCAF8,FRMPD4,MAML1,ZEB2,ZC3H11A,RHOBTB1,SV2A,WDR20,GRIN3A,SLC29A4,SHANK1,DTNA,MAMLD1,DYRK1A,DNM1L,AASDH,WDPCP,HIPK3,SIDT2,EGFR,MBNL2,KCTD3,EPB41,EPHA5,EPHB1,RTN3,SIRPB1,ABCA8,DLC1,RACK1,TESK2,PPP1R1B,KIAA1109,FGF13,FHL1,CAP2,PDLIM5,USP21,FYB1,GABBR1,AHCYL1,ERAP1,DISC1,SRRM4,ALDH1L1,TUBGCP4,GGT7,MALT1,KIRREL3,GLDC,LOXL3,MCHR1,ATP2B1-AS1,GRIA2,PLCD4,NR3C1,KIF3A,RABL2A,SOX21,RNFT2,ADAMTS6,NXPH3,FRMD5,ARHGAP36,MIER3,AGBL5,HNF4G,ZDHHC15,LRRCC1,SCIN,LRRTM3,KCNK2,MAG,MBNL1,MOBP,MT1M,P2RY13,NEFM,NF1,SLCO1C1,NOS1,TBC1D25,IGSF11,OPA1,PCSK2,CDK18,GNG2,NLGN3,PLCB2,PLEC,MTRF1L,PURG,MED1,PPP2R5C,RELN,MDGA2,CNTLN,TMEM260,PTPRH,PTPRO,RAB5B,RAP1GDS1,ZCWPW1,ZNF493,ARID4A,DBX2,HKR1,GTDC1,RFX4,RNF220,EXD2,KIRREL1,SCN3A,SCN8A,ITSN1,KIF16B,CPEB3,FNDC3A,BCAN,SLC1A3,SLC8A1,RAB3GAP1,SLC8A3,SHANK2,ATF7IP,SPHKAP,ZKSCAN3,SMARCC2,RIMS1,SNCA,MBD5,CABCOCO1,DOP1A,MYT1L,ZSWIM8,SPTAN1,DDN,TAB2,ATP10B,CLASP2,ZC4H2,NKAIN2,STAU1,SEPT8,SULF2,SYNE2,SYP,SYT4,TACR1,KAZN,KLHL4,EHBP1,RPGRIP1L,OBSL1,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,HIF3A,CYB561A3,CRB1,C18orf54,ITGB3BP,AKTIP,SLC44A1,TIAM1,ERCC6L2,TPM1,TPM3,SMUG1,TRPC1,KCNE5,PRR18,TUBB1,UBE3A,FLRT2,PLEKHH2,KLC2,GUSBP1,ZIC1,ZNF19,SPIRE1,FTSJ1,MEIS3,PRTFDC1,HPS4,SLC17A7,MVB12B,UBE3B,ACTR3B,KLHDC1,NETO2,FAM198A" MicroRNA hsa-miR-548p:PITA hsa-miR-548p:PITA_TOP PITA 2.11E-93 1.19E-89 1.18E-92 1.09E-91 227 895 "FMNL2,GALNT16,ADD3,USP31,KLHL13,PCDH19,OSBPL6,FAM135A,DPP10,ANK3,APBB2,APC,GAS7,ALS2,API5,CADPS,DDX3Y,ATP1A2,NIPA1,WASF1,BTRC,CACNB4,THSD7A,PTBP2,CAMK2A,CAMK2G,MAP7,CBFA2T2,MAGI1,FOXN3,SOCS6,CHN2,B4GALT6,NRXN3,CLCN4,CLTC,QKI,HECTD1,ARMC8,COL4A5,IGDCC3,OSBPL3,ATRNL1,NCAN,APPL1,ST18,DOCK4,ARHGAP24,DCAF8,FRMPD4,TOX,ZFYVE16,LONRF1,MAML1,IST1,YTHDC1,ELMSAN1,MYEF2,ZC3H11A,WDR20,CHRDL1,DLG2,GRIN3A,CPEB2,SLC12A6,DYRK1A,ABCC5,ST8SIA3,EDNRA,HIPK3,GPR61,APH1A,MBNL2,EGR3,TENM1,ELAVL3,PAN3,EPB41L2,GPHN,EPS8,ETV1,ACSL4,ATP8A1,CAP2,SEMA4D,PSD2,CELF1,GABRB3,IQGAP2,SESN1,TOX3,RAB40B,GPM6A,TDRKH,CNTRL,GRIA2,GRIA4,FAM19A2,TMEM25,IL1RAPL1,ADAMTS6,MAP4K5,HMGB1,AGFG1,HSF2,SOWAHA,IGF1,RBPJ,OLFM3,KCNA6,KCND2,STXBP5,KTN1,SMAD1,MAP2,MARK1,MBNL1,CHIC1,LRP1B,MEF2C,MEIS2,MIA2,POC1B,AFF1,MN1,SAMD5,NCAM1,NF1,NFIA,NFIX,NRCAM,HCN1,PDE3A,PDE4D,GPR85,CAMKV,ANLN,PIK3R1,XRN1,PLP1,PCDH18,STRN3,EPB41L4B,SH3KBP1,PPP3CA,VSTM2L,PKN2,RELN,USP47,RBBP6,RBBP8,MSANTD2,RDX,SLC6A15,REV3L,FIGN,TTLL7,ZFHX4,RMI1,CSRNP3,SCN3A,LRRTM4,FAM19A1,SOX6,GALNT10,SCG5,ZFP30,PPP1R9A,SH3GL3,CPEB3,MAGI3,CHD9,WDR47,RAB3GAP1,NAPB,ELMO2,CPEB4,PALLD,PDZRN3,SOX1,MYT1L,KIF21B,CDK19,LMO3,SRPK2,ZNF621,CLASP2,SSTR1,ERBIN,SULF2,SYT11,SYPL1,CAMTA1,MCF2L,FAM208A,FBXW11,TBL1X,TCF4,TRIM2,PSD3,PUM2,AP4E1,TIAM1,ZFP91,TSC1,UBE3A,OSBP2,VGF,VSNL1,NSD2,KCNT2,NDRG4,ZBTB38,ZFAND5,SMARCAD1,SLC38A1,CSDE1,EVI5,STOX2,SLC17A6,GOPC,PAK5,SMIM8,HNRNPA3,VANGL2,FRMD6,CPNE4" MicroRNA hsa-miR-328:mirSVR_lowEffct hsa-miR-328:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-93 1.35E-89 1.34E-92 1.23E-91 277 1316 "KCNH8,ACADM,CSMD2,SLC25A25,GALNT13,SORCS1,GRAMD1B,ADORA2A,SNX30,MTA3,PCDH19,KCTD16,ALAD,MRTFA,CCDC146,SUGT1P4-STRA6LP-CCDC180,APBA2,EPB41L5,DGKZ,UPRT,USP37,ASGR1,RASL11B,B3GALT2,N4BP2L1,NRP2,CFLAR,KSR1,BMPR1B,SYNJ1,ARHGEF7,CACNA1G,HAP1,SYT6,VSTM2A,CERS5,ARHGEF1,CD38,AP4M1,MAGI1,NUMBL,CHGA,TAOK2,RAB33A,PLAA,KIAA1549L,CNR1,CABP1,PNKD,C2CD2,SH2B1,SNCAIP,CSF2RA,ATRNL1,PPP1R16B,CTNND2,BOC,ARHGAP32,KATNAL2,ARHGAP24,PHF19,ZFYVE16,PHYHIP,DAPK1,SPOCK2,IP6K1,GIT2,ARMCX4,YTHDC1,DNAJC6,CCDC3,GRIN3A,HS3ST4,NYAP1,CD99L2,DOCK2,PDCD6IP,DNAJB6,USH1C,RASGRP1,YAF2,GPR61,SUGP2,TNK2,ENO2,EPHA5,ANKRD13B,EPS8,F5,TOMM40L,STRADA,KAT8,SPSB4,BAIAP2,TMEM164,FHL1,MEX3B,ANKFY1,ZCCHC17,HHIPL1,DOT1L,DISC1,ALDH1L1,TUBGCP4,TUBA8,GJB1,GLS,STARD3,OS9,GNAS,GNG3,GRB10,GRIA1,GRIA2,GRIK5,NR3C1,GRM7,BTN2A1,LINC00839,CLASRP,ATXN2L,MIER3,ELOVL5,HMGB1,GABARAPL2,NEGR1,CPT1C,OPALIN,KNDC1,SCIN,LRRTM3,ITGA7,ITGAV,KCND3,KCNJ9,KCNK3,KCNMA1,KIF5C,ZFYVE27,MAP4,MBP,MEIS2,SCAMP5,XRRA1,MMP16,MN1,MOBP,MPP2,CPNE9,MRPL42,PTOV1,SCG3,LYRM9,MYO9A,ZC3H12B,NFYA,NNAT,NME4,VWA2,SLC11A2,NTRK2,NUMA1,TBC1D25,OPRL1,CLDN11,PDE1A,GDAP1L1,NLE1,PLXNB1,PLXNB3,PNMA3,LRP12,RETREG2,PILRA,GRAMD1C,TMEM104,PLPPR1,UHRF1BP1,TMEM260,PTPRO,TUG1,CEP97,SLC25A48,FAM66C,MSANTD2,GTDC1,ARHGEF10L,RNF220,SETD5,CARF,GSTCD,CYB561D1,CCDC102B,EPHA10,RPL15,BAALC,GLDN,TCP11L1,MAP6D1,PAQR6,MEG3,ST6GALNAC6,NCBP3,MAPK12,MIR124-2HG,HOGA1,SCN2B,TRIM46,FERMT1,ASAP3,WDR37,ZNF365,RUFY2,FAM214B,LRRC55,CCDC88A,TMEM132D,SLC22A4,NAXD,ABTB1,OGDHL,INTS9,RCOR3,SNRPN,WDTC1,ZSWIM8,PEG10,IQSEC2,TSPYL2,NFASC,LHPP,C11orf87,ATP10B,SEPT8,PHLDB1,SEPT3,TACC1,AGTPBP1,ANO4,ZEB1,HIF3A,TF,LEFTY2,ARL10,ENHO,TIAM1,LRRC8A,TMPO,DAAM2,PIK3R5,RGMB,SYNPO2,PRMT8,NEIL2,PPIL6,ANO5,TTTY15,UGT8,MTCH1,CCDC136,BEST1,CLIP2,LAT2,ZNF781,ZNF23,TRIM9,GPR158-AS1,SPIRE1,DHX33,SEMA3B,GAL3ST3,URM1,SLC17A7,CASC15,NUP214,FAM219B,LAS1L" MicroRNA hsa-miR-1288:mirSVR_lowEffct hsa-miR-1288:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.07E-93 1.73E-89 1.71E-92 1.57E-91 249 1075 "ADAR,SORCS1,PLEKHH1,ADORA1,ESYT2,DPY19L2P4,FAM135A,BIN1,OGT,MYH7B,SUGT1P4-STRA6LP-CCDC180,TNRC6C,USP37,SFMBT2,SEMA4G,IGDCC4,NUMB,ASTN1,BCL2L2,BMP7,SYNJ2,MTMR3,C5,OSGIN2,CDK5R2,CACNB2,CACNB4,CALB2,CAMK2G,ARHGEF25,KRIT1,INA,ARHGEF1,TMEM257,CD81,SEPT7,LGI1,CBARP,PLEKHB1,CASC2,SYNPR,B4GALT6,STOML1,FBXO7,SRP14-AS1,LY86,IQCK,TBPL1,ZNF521,NECTIN3,CRMP1,ANKRD44,AATK,CSF1R,CSNK1E,NCAN,RIMS4,PHF14,GREB1,ST18,FAM131B,ARHGAP32,TOX,DAPK1,DGCR5,MFAP3L,FBXL5,DDX46,POM121,SPOCK3,SV2A,SGSM2,CHRDL1,EXOG,DNM1,HS3ST2,DNM2,DMTF1,ACOT8,E2F5,AASDH,SGK2,FSD1L,EIF4G2,SORBS3,DCTN4,EMX2,VPS13B,KCNMB2,ANKRD13B,RASL12,EXTL1,CEP78,SUCO,PCYOX1,FLT1,NOP56,NBEA,KHDRBS3,CELF1,B3GAT1,TBR1,ABLIM2,GABRG1,BRPF3,ZMYND11,B4GALNT1,GALR1,IP6K3,GAP43,DISC1,WASF3,GGT5,RAB30,PRUNE2,RAPGEF4,GRID1,GRM5,KAT7,ZBTB49,NXPH2,LINC01102,GABARAPL2,IGF1,KNDC1,IL6ST,KCNA4,KCNJ9,KCNK3,A1BG-AS1,STMN1,MAP2,MATN3,MBP,SYT9,XRRA1,MRPL42,BCO1,MSRA,MXI1,CCDC13,NEK1,CNOT4,PCBP3,GPR137C,PCDH9,PCSK2,PDGFRA,PDYN,ZNF655,PLTP,C11orf49,MAPKAP1,PPP3CA,MAPK8,WBP1L,GON4L,RASGRF1,RASGRF2,DBX2,RDX,DUSP15,FIGN,KIF7,SEC61A2,CCDC25,SPIN3,ADAL,STK32B,SYNDIG1,RTN1,STX1B,RYR3,ZNF331,MAPK12,ATXN7,ZNF821,MYO18A,DOCK10,FNDC3A,SLC1A3,KANSL3,RADIL,ELMO2,SLC22A4,SORCS3,INTS9,IFT122,MYO16,USP33,SON,SOX15,CLUAP1,UHRF1BP1L,IDI2-AS1,POGZ,STOX1,EPB41L3,MAPK8IP3,CEP68,NSFL1C,VAMP1,TAC1,CAMTA1,ADGRL3,KIAA1107,WWC1,TBCEL,TCF7,TPCN2,SZT2,WDR7,FAM189A1,ARHGEF12,TNS2,CYB561A3,VWCE,FAM200B,DICER1,ZFPM2,BEX4,KAT6B,TPD52,WBP2,PRMT8,PPIL6,HSPBP1,SLC35A4,FLRT2,CCDC136,VLDLR,BEST1,WIPF1,GUSBP1,ZNF19,CFAP52,ZNF138,EML6,WNK1,ZXDA,LMAN2L,PPP1R3F,FZD3,FAM219B,JMJD1C,ZNF248,KLHDC1,FRMD6,SLC4A10" MicroRNA hsa-miR-606:mirSVR_highEffct hsa-miR-606:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.37E-93 1.89E-89 1.87E-92 1.73E-91 255 1126 "RALGAPA1,SDE2,ACADM,CLK4,NCKAP5,ARID1A,BRAP,ERMN,KIDINS220,SLC44A5,HACE1,HFM1,FAM135A,LRCH2,EP400,APC,ALS2,TNRC6C,API5,SHTN1,ASPH,ZBTB10,DPY19L3,ATP6V0A1,DOCK11,TTLL9,SEC11C,DCAF5,IL33,CA8,KALRN,VXN,RUNX1T1,METTL6,USP6,TMEM257,DGKI,CDC27,TIGD7,CLGN,CFL2,NDST3,C7orf61,KMT2C,DNAJB5,FHL5,CNR1,IQCK,ARMC8,COL9A1,AKAP5,CRHBP,LRRC3B,CSNK1G3,SOCS5,CNTNAP2,PHF14,CTNND2,ST18,ZSCAN23,CX3CR1,HDAC9,ARHGAP24,LIN54,MATR3,DBI,SPATA2,ZEB2,CEP170,DDX46,SACS,DMD,USP3,CPEB2,DNAJB6,DYRK1A,DNM1L,EBF1,FSD1L,MBNL2,KMT5B,ELAVL2,RGS17,EPB41,EPB41L2,EPS8,DENND4A,MRPL37,RCSD1,EYA1,EZH1,F5,FHL1,POLK,SYNCRIP,SGIP1,SMC2,UFM1,ERGIC3,ST6GALNAC3,STAU2,NRG3,GAD1,ZMYND11,RAPGEF6,MTHFD2,WASF3,PPARGC1A,MALT1,GLI2,GLUL,PCDH11X,GPR34,GPR37,FAM19A2,RABL2A,PSIP1,MAP4K5,RASSF8,TOX2,ZHX1,MIER3,SMAP1,MSL1,IGFBP1,RBPJ,PLD5,USP54,JAK2,SLC35G1,KCND2,KCNJ5,LIMS1,NCOA7,MAP4,MARK1,MBNL1,IL17D,MIA2,MN1,MSR1,SCG3,MYO9A,MYT1,P2RY13,NDUFA5,NFE2L2,NRGN,GPR137C,PAH,PAX6,ETFRF1,PCDH8,PDGFRA,NALCN,PIK3C2A,ANLN,PLCL1,HMGCLL1,PURG,RC3H2,LRP12,SCHIP1,PPM1B,LRRN3,PPP2R5C,PSMD13,PTPN13,OCIAD1,EML5,FAM120C,PTPRZ1,USP47,RAD17,ZNF793,OXR1,SLC6A15,RGS3,RPRD1A,SETD5,ROBO2,PCMTD2,ABCA11P,RMI1,SEC14L1,SFPQ,HSPA4L,SCG5,KIF21A,KIF16B,CPEB3,SHC4,FNDC3A,NLGN1,WDR37,RUFY2,CCDC88A,ELMO2,BTBD7,SMARCE1,RIMS1,SNAP25,ENKUR,GLT8D1,KDM4C,ZC3H13,SRPK2,ZC4H2,NKAIN2,ELOVL4,NEK4,SYT11,FGD4,SYNE2,VPS13A,NUDT10,SYT1,ANKRD12,KAZN,MTCL1,CAMTA1,DNMBP,TCF4,SATB2,TCF7L2,WDR7,PCDHGA11,PCDHB7,PCDHB6,SIRT1,AP4E1,TPM2,DCBLD1,ANO5,FAM155A,MEAF6,WIPF1,WRN,PLPPR5,SMARCAD1,WNK1,SLC30A4,EMSY,MFF,PRDM10,PCDH15,SLC17A6,FAM13C,KAT6A,SMIM8,PHTF2,SLC39A12,SSPN,KLHDC1,SENP7" MicroRNA hsa-miR-526b:mirSVR_highEffct hsa-miR-526b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.30E-93 2.41E-89 2.39E-92 2.20E-91 244 1035 "SDE2,KCNH8,ACLY,CLK4,ABHD6,ACTN2,FAM43B,CSMD2,ADD2,AXIN2,ADORA3,BEND6,AP2A2,INTS2,MTUS1,FAM135A,PDZD4,OGT,ANK2,USP28,APOC1,RGS20,PDE8B,STK33,CCDC74A,ZBTB10,ATP6V1G2,BACH1,ADGRB3,RGS9,DST,ST3GAL5,SYNJ2,GPC2,CACNA1D,CALB1,VXN,SPAG9,LDB2,METTL6,USP2,CD38,C1orf52,DCLK1,LGI1,CHN2,ZFYVE9,CLCN4,QKI,ACBD5,ZNF521,ZFP28,HS3ST5,RNF14,GDA,CLIP3,CS,CSF2RA,PHACTR3,UBXN2A,CTNND1,RUBCN,FGFR1OP2,FRMPD4,MYEF2,DDX46,ALKBH8,SGSM2,EXOG,DMD,CPEB2,ECM2,ABCC9,OPTN,PHF20L1,SUGP2,EPB41,DMTN,EPHB1,ENPP6,EPS8,EXTL2,NRN1,SCML2,DLC1,CHST15,TOMM40L,KAT8,ZNF589,FER,GTF2IRD2,POLR1B,POLK,IP6K2,FOXM1,ANKFY1,SMC2,USP21,KHDRBS3,ST6GALNAC3,SARAF,OGA,ZMAT1,CHL1,GABRG2,GAD1,FAM120B,MTHFD2,DNER,ADAM28,GHR,DCLK2,LNX1,PRUNE2,GPM6A,TDRKH,CECR2,GRIA4,ATE1,GYG1,MAEL,ZHX1,FRMD3,ARHGAP36,HNMT,DOCK7,LIX1,IL6ST,INPP5B,JAK1,KCNJ11,KCNK1,KLRC3,KTN1,STMN1,SYTL4,HECTD2,ARHGAP12,MBD1,POC1B,ERICH3,SCG3,NAP1L3,NELL2,NPTX2,NTRK2,PAH,PAK3,PAX6,PCSK1,PDE3A,PDGFRA,XRN1,HMGCLL1,PMP2,STRN3,EXOSC10,SPATA6,PILRA,NXPH1,PPP3CC,VPS13C,PIGG,PLPPR1,ZIK1,PTPRE,PTPRO,RASGRF1,ARID4A,RDX,SLC6A15,MRPS18A,SEC61A2,RIC8B,PBRM1,RPRD1A,ZFHX4,TMLHE,ROBO1,ARMH4,SPIN3,TCP11L1,ATAT1,CLIP1,SUPT20H,SH3GL2,FNDC3A,ST6GAL1,NLGN1,ANKRD6,ABLIM3,ZNF365,SLC12A2,SMARCE1,SNRPN,TNIK,CLUAP1,UHRF1BP1L,IDI2-AS1,CLASP2,SS18,APOM,SYN1,POPDC3,TACR1,KAZN,CAMSAP2,FAM208A,KIAA1107,AGTPBP1,ACSL6,TCF7,SLC19A3,HHIP,ZFP91,ERCC6L2,TPD52L2,TPM4,METTL3,TRIO,ANO5,TTC3,HEPACAM,UGT8,CCDC14,XPO1,ZNF19,AGMO,MKRN3,LYPD6,FSTL5,SYNC,UPF3A,PRTFDC1,LRP8,PRDM10,SLC17A7,EPM2A,GOPC,CASC15,KLHDC1,FXR1,CBLN2,FAM198A" MicroRNA hsa-miR-203:PITA hsa-miR-203:PITA_TOP PITA 4.89E-93 2.75E-89 2.71E-92 2.50E-91 190 625 "RALGAPA1,ARID1A,XKR4,NDRG3,FMNL2,ZNF608,PCDH19,KCTD16,RTL9,OSBPL1A,OSBPL8,SEMA6A,BCAR3,AMPD3,MAP4K3,APC,API5,SLC7A14,ARHGAP5,ARNTL,CDK13,SLC4A4,STX16,ATP2B1,DPY19L3,MPDZ,BCL2L2,BCL7A,SYNJ1,WASF1,CACNA1E,CABP7,THSD7A,INA,CDH10,ZMYM4,MAGI1,NUMBL,FOXN3,SOCS6,CLTC,QKI,HECTD1,CNTFR,AKAP7,AKAP6,CLOCK,RBM39,CREB5,GDA,ARHGEF10,ST18,EDRF1,FGFR1OP2,MATR3,DGKB,NR1D2,DYRK1A,EDN1,FAM135B,EDNRA,MBNL2,EGR3,TENM1,TMEM35A,PAN3,EN2,ANKRD13B,NCALD,ETV1,OLFM1,PRKAG2,FOXG1,AFF2,NBEA,DACH2,GABRA5,GABRB3,CAB39,GATM,PPARGC1A,GLS,TOX3,INSM2,GNAO1,NUDT21,PCLO,RAPGEF4,RAPGEF1,ADAMTS8,CIT,ADAMTS6,BACH2,HPCA,NEGR1,HTR2A,LRRCC1,LRRTM3,KCNC2,KCNMA1,KIF2A,IPO5,MAP2,MBNL1,MEF2C,MEST,MGAT3,MID1,MXI1,ZC3H12B,NEUROD1,NFYA,NOVA1,TBC1D25,CNTN3,PCSK2,PDE4D,GPR85,PIK3C2A,PLP1,FAT3,POLG,NXPH1,MAPK9,MAPK10,PTCH1,UHRF1BP1,PTPRG,FAM120C,RADX,RGS7,SLC25A36,ZFHX4,ZNF532,RAVER2,ROBO1,TMEM100,ATXN1,SCN2A,SCN3A,ELMOD1,DOCK10,CHD9,WDR37,ABLIM3,SLC1A2,BTBD3,YPEL4,SLC12A2,TET1,CPEB4,FAM126B,DOP1A,SP2,SP4,NMNAT2,CLASP2,LARP4,NKAIN2,CEP68,PHLDB1,ADAMTS17,TAC1,ATP11A,CAMSAP2,TCF4,DMXL2,KIAA0930,TRIM2,RPGRIP1L,TCF12,ARHGEF12,DICER1,TLL2,HEY2,KAT6B,TRPS1,SGK3,FAM155A,AMOT,VSNL1,TMEM237,SMARCAD1,PRDM10,SLC17A6,C12orf4,KAT6A,PHTF2,NETO2,GAN" MicroRNA hsa-miR-505:mirSVR_highEffct hsa-miR-505:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.40E-93 3.03E-89 2.99E-92 2.75E-91 239 995 "ABAT,CLK4,ACTN2,KLHL32,PLEKHH1,PWWP2A,ESYT2,KIDINS220,WDR35,C1QTNF3,SPARCL1,FAM135A,DPP10,LCORL,PPFIA1,BCAS1,SHTN1,MIER1,TMEM263,PLA2G4C,ATP2B1,SLC2A11,ADGRB3,MPDZ,SCAPER,VXN,CH25H,MAP7,USP6,INA,C1orf52,CDC27,CDH2,LRRFIP1,MAGI1,TIGD7,SRSF11,CHGB,CHI3L2,CLTB,QKI,NIPBL,AKAP6,MAGED1,MYRIP,CP,CHD1L,HINFP,TRIM69,SIPA1L1,VCAN,DZIP3,CTH,DOCK4,KIAA0319,DDX46,SPOCK3,MED12,SLC29A4,CPEB2,DPYSL2,PDCD6IP,ABCC5,E2F5,WDPCP,FCF1,TMTC1,FSD1L,PHF20L1,KMT5B,EGR3,RCAN2,DMTN,LRRC23,ZIC4,FER,POLR1B,PRKAG2,CAP2,FAM49B,TPK1,CELF1,PNMA2,MSANTD4,TBR1,OGA,PHYHIPL,GABRA1,GABRA3,GABRG1,GABRG2,ZMYND11,MTHFD2,DISC1,GART,KIAA1841,PPARGC1A,GLYR1,GPR75,GLS,TNRC6A,ZNF638,GPM6A,FUT10,LILRA1,GRIA2,GRIA4,CLASRP,LINC01551,AP4S1,PSIP1,ADAMTS6,GYG1,TOX2,LINC01102,HLF,HMGB1,C2orf72,LRRCC1,LIX1,ZNF385B,KCNC2,KCNMA1,KIT,LIMS1,HECTD2,NCOA7,ZNF667-AS1,C1orf194,LRP1B,MEIS1,MEIS2,KCTD6,AFDN,CD200,MYCN,MYO9A,HNRNPM,NCAM1,NDP,NEUROD1,OTOGL,VWA2,NOVA1,DNHD1,NUCB2,PAH,PAK3,PDCD2,PDGFRA,CDK14,PMP22,LRP12,SCHIP1,MBOAT7,EPB41L4B,POU3F4,MINDY2,PPP3CB,EPDR1,MAPK9,HYDIN,VPS13C,PSMD13,BDNF-AS,PTK2,PTN,PTPRO,SH3TC2,SLC6A15,RET,RFX4,SLC25A36,RNASEL,ZFHX4,SETD5,ARMH4,ACER3,FAM192A,LRFN5,SCN8A,SCP2,KIF21A,ITSN1,HKDC1,ANKRD6,EPN2,SLC6A1,SLC8A3,SPHKAP,CPEB4,SLN,SORCS3,ANKRD36,SNAP25,CMTR2,SNRPN,SON,MYT1L,SP4,KDM4C,CLASP2,DIP2A,SEPT3,AJAP1,KLHL7,NAT16,PCDHB3,PUM2,USP32P1,TEX15,CRB1,ERCC6L2,TMPO,TPM1,ZNF346,PPIL6,RFTN2,ZKSCAN5,CADM1,AMOT,UBTF,VAV2,WIPF1,ZNF781,SF1,PCDH20,ZBTB14,KCNT2,MKRN3,ZNF138,ZSCAN26,ZXDA,PRDM2,PRDM10,SCG2,UBE3B,SLC4A10,GAN" MicroRNA hsa-miR-4319:mirSVR_lowEffct hsa-miR-4319:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.03E-93 3.95E-89 3.89E-92 3.58E-91 285 1394 "ABAT,ACADM,ACHE,SYS1,FAM43B,NDRG3,PLEKHG5,ADD1,ERMN,LRFN2,BEND6,MTUS1,SNX32,TXNDC16,CC2D2A,MARCH4,PI16,PKP4,KCNAB2,APC,DGKZ,API5,AQP6,SPTBN4,SLC4A4,SLC2A11,NOL4,DOCK11,SNAI3-AS1,CFLAR,KSR1,SCAPER,CACNA1B,CACNA1E,DDR1,DIRAS1,ISPD,ARHGEF1,SCARB1,ARHGEF2,CDH8,CBARP,CASC2,RAB33A,RAB28,KIAA1549L,NRXN1,FADS2,DNAJB5,ARHGEF6,AKAP7,ANKRD35,SUMF2,MFSD4A,ZNF385A,SEC31B,CREM,ENTPD4,HAPLN1,CRY2,ANKRD44,NCOR2,GDA,TENM4,SIPA1L1,NCAN,APPL1,PHF14,GREB1,FAM131B,ECE2,CCDC144A,CYBB,RIPOR2,DAPK1,DNAL1,PITPNC1,ELMSAN1,PLEKHM1,HEPH,RUSC2,ZC3H11A,RPS6KL1,DPH1,DTNA,DTNB,ABCC5,FAM135B,PHC2,SYT15,CNNM1,PHF20L1,TMEM132E,PLEKHA1,ANKRD13B,MRPL10,ANKMY1,SCML2,FCGR1A,FKTN,ZNF589,FER,PRKAG2,SMC2,ARFGAP2,DACH2,GPR153,HHIPL1,AP4B1,NRG3,B4GALNT1,TMEM8B,SIGLEC8,SEPT9,LRRC37A6P,GCNT2,GGT7,CRCP,TCERG1,GLS,ZNF638,GNAS,LILRA2,CCDC184,LPAR4,TMEM121B,CECR2,PCLO,RAPGEF4,GRB10,GRIA2,SPACA9,RASSF8,TOX2,PADI2,PTGDR2,MAN1B1,HRH3,TNFAIP8L3,SYNPO,HMGCR,HNF4G,OPALIN,NKD1,LIX1,IL6R,NME9,ITGA7,C2CD4C,METTL21A,KCNA1,KHK,SYTL4,HECTD2,NCOA7,MAP2,MAP6,MARK1,ADAM11,MIA2,MOBP,MSI1,C10orf105,MYO7A,NCAM2,NEFM,NUCB2,SETD4,IGSF11,DPY19L2P2,PDE3B,PDGFRA,ZDHHC8,CAMKV,ZNF655,RETREG2,POLG,POU3F2,MINDY2,PPM1B,PTPA,PPP2R5C,PRKCZ,MAPK10,PROX1,VPS13C,PSMD13,PTH1R,PTK2,PTPRE,C1orf109,FAT4,ARID4A,ZDHHC14,ZYG11B,DPF2,RET,FIGN,UBR7,ZFHX4,CARF,KIRREL1,ATP8B4,STK32B,EMID1,LRRK2,MEG3,SCP2,ASIC4,CASC3,ITSN1,KIF16B,MYO18A,MAGI3,CHD9,ST6GAL1,DHX30,SLC9A5,SLC11A1,NAPB,LGI3,ABTB1,ANKRD36,SNRPN,UNC80,DOP1A,WDTC1,ENKUR,GLT8D1,ZC3H13,SPTB,NFASC,SS18,ELOVL4,SEPT8,ADHFE1,SEPT3,FGD4,SYN2,SYPL1,SLC37A2,TACR1,TMEM136,SATB2,TCF7,RPGRIP1L,WASHC4,TF,DICER1,CRB1,GPR161,AKTIP,BHLHB9,LRRC8A,PIK3R5,RASD2,SMUG1,TRPS1,GORASP1,BCL2L13,PORCN,ELFN1,GPR158-AS1,CRB2,LYPD6,TMEM198,EML6,PRDM2,CSDE1,STOX2,ADAMTS9,PCDH15,SLC17A7,CAB39L,WIPF2,PLSCR4,PARP11,GOPC,UBE3B,TMEM63C,ZNF248,RNF170,MSRB3,TTC7A,SOCS4" MicroRNA hsa-miR-596:mirSVR_lowEffct hsa-miR-596:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.48E-93 4.20E-89 4.13E-92 3.81E-91 265 1216 "VWA5B2,KLHL32,ADCY6,ZNF608,GPR158,AK2,SRPX,GOLGA7B,KCNT1,OGT,SMIM29,PHF12,CNIH2,SUGT1P4-STRA6LP-CCDC180,APAF1,APBB1,DGKZ,UPRT,ALS2,USP37,MADD,IGDCC4,LINC00173,CAPRIN2,ATP1A2,SLC2A11,ADAM15,RGS9,BCL2L2,KSR1,SCAPER,JAZF1,CFAP410,CACNA1E,DDR1,KALRN,CANX,SCARB1,CD38,LOC730101,LARGE1,CBARP,MS4A7,CLCN3,COG1,FADS2,NIPBL,RAB26,AKAP5,SLC4A8,ABI3BP,IGDCC3,SNCAIP,SEC24C,OSBPL3,PHACTR3,FAM169A,ARHGEF4,DCAF4,MAML1,DGKB,SCRN1,MYEF2,CNIH3,C2CD2L,KLHL3,TMEM130,SMG7,SV2A,DMD,HS3ST2,DMTF1,DPH1,PDCD6IP,DSCAM,ECM2,DNAJB6,ABCC5,SYT15,CNNM1,EGR3,RASA4,ELAVL2,ELN,EPHA5,NCALD,SPEG,TMEM74,EZH1,FAM198B,ATP8A1,TESK2,ZNF589,GTF2IRD2,FGF1,TMEM164,FOXF2,WDR83,HVCN1,PNMA2,SDCBP2,NEURL4,GABRA5,TRAF3IP2,FAM120B,SALL3,SIGLEC8,GGT5,RUNDC3A,GLRB,TOX3,TNRC6A,GLUL,PCDH11X,STARD3,DCLK2,GNAS,ADGRA3,ATF7,GRID1,KIF3A,ZBTB49,AP4S1,LINGO1,NCKAP1L,HNMT,NEGR1,TCEAL6,EID2B,ZNF181,MYLK2,INSM1,KCNK2,SYTL4,NCOA7,ASPRV1,ZFYVE27,MAT2A,MBD1,SYT9,LDLRAD3,COMMD5,ADAM22,MYO9A,RTL5,FXYD6,NDUFA5,SLC11A2,GPR137C,CDK18,GPR173,PFKFB2,ZDHHC8,SSH1,SEMA5B,PIK3CD,FAM218A,ST8SIA5,POLG,TMEM235,NDUFS7,LRRC49,PIGG,RAB3A,RALGDS,IQSEC3,SLC25A41,RBBP6,FIGN,KLHL11,ZNF532,KIRREL1,CCDC25,RPL15,SPIN3,ADAL,RTKN,CLIP1,RXRG,AMER2,MAPK12,MIR124-2HG,PRCD,SOX6,TRIM46,STUM,SGK1,ITSN1,FAM102A,CPEB3,SHMT2,HKDC1,CNKSR2,PAAF1,WDR37,EPN2,WDR47,LRRC55,NAPB,BTBD7,SLC20A2,TET1,OGDHL,CDK5RAP2,SMARCD3,KIF13A,SON,BDP1,KDM3A,HECW1,PEG10,SPTB,NFASC,NCDN,SEPT3,ZC3H4,FNDC9,PLCB1,TMEM150C,SYP,SYPL1,DDHD2,MLST8,ZFP90,PCDHA5,CYB561A3,ZFPM2,CRB1,SPX,GPR161,TGFBR3,SLC44A1,ZNF346,SYNPO2,TRO,NUTM2A,PPIL6,ANKRD20A2,TTTY15,UBTF,BCL2L13,MEAF6,BEST1,LGI4,TRIM9,ZNF74,MKRN3,FSTL5,ANKS1B,PLPPR5,DHX33,EMSY,PRDM2,DNALI1,NAV3,SLC17A7,MVB12B,PARP11,DOCK8,CASC15,NUP214,CERS6,FAM219B,RNF170,TTC7A" MicroRNA hsa-miR-199a-3p:mirSVR_highEffct hsa-miR-199a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-92 6.77E-89 6.65E-92 6.12E-91 234 958 "ABCF1,KCNH8,KDM5D,ARID1A,ADD3,KIDINS220,SLC44A5,KLHL13,KCTD16,HACE1,OSBPL1A,TAOK1,ALCAM,BCAR3,ANK2,PHF12,CNIH2,UPRT,RGS20,CADPS,ZBTB10,ASTN1,ATM,ATP2B1,NOL4,DST,SYNJ1,FUBP1,CACNB2,CABP7,KALRN,RUNX1T1,MTMR7,DCLK1,CDO1,TIGD7,CFL2,SRSF11,MS4A7,NDST3,QKI,MAP4K4,ARMC8,COL4A5,SLC25A27,LETMD1,MYRIP,FAM171B,RNF14,LRRC3B,OSBPL3,VAC14-AS1,PHF14,FGFR1OP2,ARHGAP24,ZEB2,G3BP2,WDR20,FAM107B,DLG2,USP3,SLC29A4,DRD1,DTNA,ECM2,EBF1,EDN1,ATL1,SGK2,SH3GLB1,FAM13A,EIF4G2,ELAVL2,CALCRL,EPB41L2,LRRC17,GPHN,CEP85L,AMZ2,EFEMP1,FCGR3A,ZSCAN30,TESK2,GORAB,MED12L,PSD2,ZCCHC17,TACC2,TMEM107,HVCN1,PDLIM5,MSANTD4,HHIPL1,OGA,PHYHIPL,DKK3,CHL1,ZMYND11,MYOZ2,TUBGCP4,TUBA8,SULT1C4,COPS8,PCDH11X,ZNF638,GPD2,GPM6B,LPAR4,EML4,GPR37,RAPGEF4,KIF3A,TMEM25,MAEL,ZHX1,MIER3,HNMT,IFI16,USP54,LIX1,ZNF678,KCNC2,KCNH2,KCNN2,KIF2A,KTN1,HECTD2,NCOA7,MBNL1,MDM4,MEIS2,SRSF12,MOBP,MOG,ERICH3,ADAM22,NRBP2,NAP1L1,NCAM2,NF1,NOVA1,DNHD1,PDE4B,PDGFRA,SERPINE2,FAM216A,PLIN1,NXPH1,PPP2R5E,CEP41,PRKCB,DCHS2,SYTL2,MDGA2,CNTLN,BDNF-AS,PTPRE,PTPRZ1,PPP2R3C,MARCH1,CEP97,OXR1,RADX,RGS4,PRIMA1,RORB,RPL15,ZC3H14,PTGR2,RTKN,LRRTM4,SCN8A,LINC00461,SCP2,ELMOD1,ZFP30,NTNG1,MAGI3,WDR47,SLC8A3,CCDC88A,ELMO2,SLC20A2,CPEB4,SMARCC2,ANKRD36,RIMS1,LMBRD1,USP33,DOK5,KDM3A,SP2,EMC1,LMO3,TAB2,CLASP2,SS18,FGD4,PRRC2C,PLCB1,SYP,SYPL1,ANKRD12,KAZN,DMXL2,TRIM2,WASHC4,WDR7,USP32P1,AP4E1,SYNPO2,ANO5,SGK3,TUBB1,PITPNB,BCL2L13,VLDLR,CLDND1,XPO1,MICU3,ATP6V0E2,SPIRE1,TMEM178A,KCNAB1,RGS7BP,RTN4,SMIM8,HNRNPA3,CASC15,ADAMTSL3,FXR1,DPF3,GAN,FAM198A" MicroRNA hsa-miR-199b-3p:mirSVR_highEffct hsa-miR-199b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-92 6.77E-89 6.65E-92 6.12E-91 234 958 "ABCF1,KCNH8,KDM5D,ARID1A,ADD3,KIDINS220,SLC44A5,KLHL13,KCTD16,HACE1,OSBPL1A,TAOK1,ALCAM,BCAR3,ANK2,PHF12,CNIH2,UPRT,RGS20,CADPS,ZBTB10,ASTN1,ATM,ATP2B1,NOL4,DST,SYNJ1,FUBP1,CACNB2,CABP7,KALRN,RUNX1T1,MTMR7,DCLK1,CDO1,TIGD7,CFL2,SRSF11,MS4A7,NDST3,QKI,MAP4K4,ARMC8,COL4A5,SLC25A27,LETMD1,MYRIP,FAM171B,RNF14,LRRC3B,OSBPL3,VAC14-AS1,PHF14,FGFR1OP2,ARHGAP24,ZEB2,G3BP2,WDR20,FAM107B,DLG2,USP3,SLC29A4,DRD1,DTNA,ECM2,EBF1,EDN1,ATL1,SGK2,SH3GLB1,FAM13A,EIF4G2,ELAVL2,CALCRL,EPB41L2,LRRC17,GPHN,CEP85L,AMZ2,EFEMP1,FCGR3A,ZSCAN30,TESK2,GORAB,MED12L,PSD2,ZCCHC17,TACC2,TMEM107,HVCN1,PDLIM5,MSANTD4,HHIPL1,OGA,PHYHIPL,DKK3,CHL1,ZMYND11,MYOZ2,TUBGCP4,TUBA8,SULT1C4,COPS8,PCDH11X,ZNF638,GPD2,GPM6B,LPAR4,EML4,GPR37,RAPGEF4,KIF3A,TMEM25,MAEL,ZHX1,MIER3,HNMT,IFI16,USP54,LIX1,ZNF678,KCNC2,KCNH2,KCNN2,KIF2A,KTN1,HECTD2,NCOA7,MBNL1,MDM4,MEIS2,SRSF12,MOBP,MOG,ERICH3,ADAM22,NRBP2,NAP1L1,NCAM2,NF1,NOVA1,DNHD1,PDE4B,PDGFRA,SERPINE2,FAM216A,PLIN1,NXPH1,PPP2R5E,CEP41,PRKCB,DCHS2,SYTL2,MDGA2,CNTLN,BDNF-AS,PTPRE,PTPRZ1,PPP2R3C,MARCH1,CEP97,OXR1,RADX,RGS4,PRIMA1,RORB,RPL15,ZC3H14,PTGR2,RTKN,LRRTM4,SCN8A,LINC00461,SCP2,ELMOD1,ZFP30,NTNG1,MAGI3,WDR47,SLC8A3,CCDC88A,ELMO2,SLC20A2,CPEB4,SMARCC2,ANKRD36,RIMS1,LMBRD1,USP33,DOK5,KDM3A,SP2,EMC1,LMO3,TAB2,CLASP2,SS18,FGD4,PRRC2C,PLCB1,SYP,SYPL1,ANKRD12,KAZN,DMXL2,TRIM2,WASHC4,WDR7,USP32P1,AP4E1,SYNPO2,ANO5,SGK3,TUBB1,PITPNB,BCL2L13,VLDLR,CLDND1,XPO1,MICU3,ATP6V0E2,SPIRE1,TMEM178A,KCNAB1,RGS7BP,RTN4,SMIM8,HNRNPA3,CASC15,ADAMTSL3,FXR1,DPF3,GAN,FAM198A" MicroRNA hsa-miR-212:mirSVR_highEffct hsa-miR-212:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.22E-92 6.84E-89 6.71E-92 6.18E-91 233 950 "ACADM,NCKAP5,ARID1A,AXIN2,PWWP2A,KIAA1211,ESYT2,KIDINS220,CC2D2A,SEMA6A,PCDH10,PHF12,APAF1,DDO,API5,SHTN1,MIER1,SEMA4G,TMEFF1,PDE8B,CAPRIN2,RNF182,FUBP1,CACNA1G,CACNA1B,PTBP2,SLC25A14,HIP1R,DGKI,LRBA,CDC25B,LRRFIP1,LARGE1,CFL2,JAM2,RAB28,FBXO7,ARMC8,ZNF521,HAPLN1,ABCG1,CSF1,DOCK4,RIPOR2,KIAA0586,ELMSAN1,ZEB2,ZBTB24,ALKBH8,RHOBTB1,SV2A,DMD,GNE,DTNA,E2F5,EDNRA,CELSR3,PHF20L1,KMT5B,EPB41,DENND4A,NCALD,CDKL3,EXTL2,CEP78,PRKAG2,FOLR2,TPK1,ARFGAP2,ATP6V1H,ZNF605,ST6GALNAC3,DKK3,GABRA2,ILDR2,RAPGEF6,ERAP1,INPP5K,MYOZ2,SULT1C4,AHDC1,GHR,C1QL1,GK,MSL3,CBX1,INSM2,GRIA2,SPACA9,ATE1,GRM3,GRM7,FAM19A2,HAS2,SMAP1,EID2B,MSL1,SOWAHA,TJAP1,ZNF678,LRRTM3,NME9,KCNK2,KTN1,LIMS1,SYTL4,PACRG,PIK3AP1,MEIS1,MEIS2,ADAM22,ZNF862,PABPC1L2A,HNRNPM,NDUFA5,NFE2L2,NOVA1,NRCAM,NTRK2,IGSF11,PRTG,SLC10A4,CDK14,SERPINE2,CCSER2,JAKMIP1,PLP1,MAPKAP1,ING3,EPB41L4B,PPP2R5C,PPP2R5E,MAPK3,HYDIN,RELN,SNRK,MTMR10,PTPRD,PEX2,FAM184A,ENOX1,OXR1,RADX,KHDRBS2,GAL3ST4,GTDC1,RFX3,RFX4,ZFHX4,SETD5,EXD2,RAVER2,PRR5L,CNTNAP3,LGR4,RTKN,KCNIP2,SALL1,CSRNP3,ATXN7,SCN2A,SCN3A,LRRTM4,SEC14L1,ARX,NTNG1,MAGI3,BCAN,SEC31A,FAM81A,EPN2,SLC6A1,SEPHS1,ARHGEF40,SLC12A2,MTERF2,RCOR3,LIMCH1,SON,SOX5,FNBP1,MYCBP2,IDI2-AS1,CDK19,C11orf87,POGZ,SS18,ERBIN,SEPT8,FGD4,SYNE2,VPS13A,MMS19,SEMA4A,DNMBP,CAMSAP2,ADGRL3,AGTPBP1,TBCEL,TMEM136,WDR7,PCDHB6,PUM2,SIRT1,AP4E1,HHIP,SLC44A1,C5orf64,RGMB,TRIO,NEIL2,TSN,HIRA,SGK3,PLEKHH2,WIPF1,ETNPPL,ZBTB14,ZNF708,NDRG4,CELF4,CSDE1,TMEM178A,SCG2,PCDH15,RGS7BP,FAM13C,RTN4,CASC15,FXR1,FRMD6,IFT88,CBLN2" MicroRNA hsa-miR-516b:mirSVR_highEffct hsa-miR-516b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-92 7.29E-89 7.15E-92 6.58E-91 247 1065 "KCNH8,ACADM,ACTN2,DSCAML1,ADD3,PLEKHH1,BCAR3,BBOX1,AMPH,CDC42BPA,DPP10,PHF12,VAT1L,USP37,CAPRIN2,ATM,ATP2A2,BACH1,ADGRB3,NAE1,CACNA2D1,CACNB2,PRC1,ARHGEF25,CERS5,USP2,CD86,CBFA2T2,C1orf52,LGI1,SRSF11,SYNPR,CNOT8,JAM2,NDST3,NRXN3,CLCN3,FAM19A5,AKAP6,SUMF2,RTTN,HS3ST5,CSF1,RGS6,MICAL2,OSBPL3,FAM169A,RIMS2,KIAA0408,KATNAL2,TCAF1,EARS2,ZNF337,ZEB2,B3GAT3,BLOC1S6,SV2B,CPEB2,PDCD6IP,DNM1L,AASDH,HIPK3,SYT15,CNNM1,OPTN,EBI3,KMT5B,GOLGA7,RGS17,EPHB1,SRRM1,EXTL2,RACK1,ZMYND10,SUCO,FLT1,NELFCD,SORBS1,SMC2,ABLIM2,FYB1,GABRA3,GABRG2,CAB39,ILDR2,GAD1,FAM120B,JPH4,RAPGEF6,ACSS1,SULT1C4,GFAP,RAB30,TOX3,WDFY3-AS2,GPD2,GPM6B,GRIA2,GRIA4,GRM3,GRM7,TMEM25,AP4S1,FAM107A,MAEL,RASSF8,TLX1,TCEAL6,MSL1,SOWAHA,TMEM240,ZNF678,KCNN3,LAMA2,INSYN2,HECTD2,ARHGAP12,SMAD9,MBD1,MBP,SYT9,MEIS1,MEST,KCTD6,MPP2,JAKMIP3,MTR,NAP1L1,SFR1,NEFM,NEK1,CLEC9A,NUCB2,OLR1,SNTG1,PAK3,PCDH9,PDGFRA,PDYN,OLA1,NLGN3,SERPINI1,PCDH18,PURG,PMP22,SDK2,ING3,SLC36A4,TATDN3,PKIA,GRAMD1C,HYDIN,SAMD9,PLPPR1,PTHLH,PTPRO,ACSM5,CEP97,RASGRF2,RDX,SLC6A15,ZYG11B,ERI2,ARHGEF10L,NUDT11,RNASEL,SUGCT,SETD5,NEK11,FBXW7,ADAL,ACER3,PTGR2,NCBP3,TMEM156,DGLUCY,CSRNP3,ASIC4,GALNT10,SUPT20H,SCAF8,SH3BGR,ITSN1,MAGI3,EPN2,RUFY2,FAM214B,CCDC88A,SLC12A2,CXXC4,ANKRD36,UNC80,SON,PDZD2,HECW1,DBNDD2,LMO3,TAB2,COLGALT2,ELOVL4,TAF9,TAL1,ADGRL3,TMEM136,VWA3A,EHBP1,SATB2,TCF7L2,RPGRIP1L,SZT2,OBSL1,FRYL,SIK3,PMS2CL,ITGB3BP,AP4E1,HHIP,SLC44A1,TK2,ERCC6L2,TMOD1,TMPO,KCTD2,PIK3R5,PRMT8,RUNDC3B,TRO,FNDC5,CCDC14,LAT2,SLC13A3,XRCC4,GPR158-AS1,CELF4,AMZ1,ZNF195,PCBP1-AS1,ZFAND5,PRDM10,RNF103,MARCH8,RNF170,MSRB3,ZDHHC20,AP3B2,SLC4A10,PRRT4" MicroRNA hsa-miR-208b:mirSVR_lowEffct hsa-miR-208b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-92 9.02E-89 8.83E-92 8.14E-91 219 841 "RALGAPA1,KCNH8,CLK4,NCKAP5,KDM5D,ARID1A,KLHL32,OSBPL1A,HFM1,FAM135A,ZFAT,LRCH2,PPFIA2,APC,TNRC6C,ASCL1,ASPA,ATP1A2,ATP2A2,ATP2B1,ADGRB2,DST,MTMR2,PRMT9,C5,IL33,PTBP2,VSTM2A,ISPD,MAP7,KRIT1,CD38,LRBA,CDH2,CASC2,NDST3,NRXN3,HECTD1,SLC4A8,ABI3BP,AHCTF1,ACBD5,ZNF521,NRG2,RBM39,RNF14,ANKRD44,GDA,RGS6,SOCS5,FAM131B,HDAC9,ARHGAP32,ARHGAP24,ZFYVE16,YTHDC1,ZEB2,MYEF2,HP1BP3,DMD,USP3,DMTF1,ABI1,E2F5,EBF1,WDPCP,PHF20L1,EIF4G2,TENM1,ELAVL2,PLEKHA1,RGS17,SLC43A2,IGSF6,RRAGB,F3,ST3GAL6,TESK2,ZNF589,FGF13,NELFCD,STAU2,ZNF512,OGA,MEGF10,B4GALNT1,KIAA1841,MYOZ2,MSTN,GDF9,GLYR1,PCDH11X,PRUNE2,CACFD1,PRDM5,BACH2,MIER3,HLF,IGFBPL1,SHISA6,IL6R,BRINP3,LRRTM1,KCNC2,KCNN3,IPO5,LIG4,LRP1B,MEF2C,SRSF12,CD200,CTNNA3,NDUFA5,NEFH,NELL2,NF1,NOVA1,OCRL,OMG,PDE1A,XRN1,GPSM2,SLC25A23,MAPKAP1,RC3H2,ING3,NXPH1,SH3KBP1,DRAM2,PPP3CA,PPP3CB,RASGEF1B,MAPK8,MAPK10,MTMR10,PTPRG,PTPRO,PPP2R3C,CEP97,SH3TC2,FAT4,ZCWPW1,RADX,RFX3,ROBO1,TMEM100,ATP8B4,MEG3,RMI1,SALL1,SATB1,FAM19A1,FNIP1,SEC14L1,SOX6,HSPA4L,KIF21A,SH3GL2,MAGI3,AMBRA1,FNDC3A,SYBU,PAAF1,ZNF365,RPH3A,SEPHS1,ELMO2,ATF7IP,SPHKAP,SMARCC2,DMRTC1,SMARCE1,RIMS1,LMBRD1,DOP1A,SON,SOX5,KIF1B,SRPK2,POGZ,RGL1,DIP2A,KANK1,FGD4,PRRC2C,VPS13A,DNAJC9,KAZN,FAM208A,TCF12,SYNE1,PHF24,PCDHB3,FRYL,ITGB3BP,SLC44A1,GALNT17,TMOD1,TP53BP1,RBFOX2,RUSC1,PRR18,DNAJC12,BCL2L13,MEAF6,REEP1,ANKS1B,MEIS3,INTS3,CA10,SLC30A4,EMSY,CADM2,SLC17A6,AMN1,FZD3,FBXO36,TRAM2-AS1,SLC39A12" MicroRNA hsa-miR-1251:mirSVR_lowEffct hsa-miR-1251:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-92 9.82E-89 9.61E-92 8.85E-91 251 1100 "ACADM,NCKAP5,SYS1,FMNL2,ADCY2,GALNT13,ADD2,BRAP,SORCS1,NME5,WDR35,ARHGAP20,UNC79,OGT,DPP10,FGD2,PKP4,CNTNAP1,APBB2,ALS2,SHROOM2,AQP4,AQP6,RGS20,ASPH,NUMB,TMEM108,ATP1A2,CDK5R1,CA12,CALB2,KALRN,PTBP2,SLC25A14,CAPN3,CAST,HIP1R,CCNH,LGI1,L3MBTL4,CHM,NDST3,FBXO7,C4orf33,CNR1,AKAP6,CABP1,LETMD1,MAGED1,CP,AKAP12,HINFP,SNCAIP,FEZ2,IPCEF1,CTNND1,NOS1AP,MYADM,FRMPD4,TOX,LIN54,MAML1,YTHDC1,POM121,SV2B,AK5,ZNF582-AS1,DMD,DYNC1I1,DPYSL2,DRD1,PDCD6IP,ARRDC4,MAMLD1,DYRK1A,ABCC5,DNM1L,FCF1,CNNM1,YAF2,KMT5B,EIF4G2,DCTN4,EPHA5,SH3YL1,CHST15,STRADA,FGF12,SYNCRIP,ZCCHC17,SORBS1,UFM1,CELF1,GABRA2,HRASLS5,ZNF44,ARPP21,GGT7,GJB1,GLRB,GLS,TOX3,GLUL,STARD3,ZNF782,GPD2,NUDT21,CECR2,GRIA1,GRIA2,GRIA4,GRIN2C,GRM3,CLASRP,RNF165,CELF3,VSIG4,LRRC75A,SOWAHA,IGF1,TJAP1,INPP5B,KCNN2,KIF5A,IPO5,SYTL4,HECTD2,MAN2A2,MAP2,MAP6,AQP11,MDM4,CD200,SAMD5,RSPO2,HS6ST3,NF1,NFE2L2,DNHD1,CYTL1,A2ML1,CCSER2,FAM216A,PLCL1,JAKMIP1,HMGCLL1,ANKRD16,PDZRN4,SCHIP1,MINDY2,PPP2R2C,RANBP3L,SLC22A23,GON4L,MDGA2,NCR3LG1,BDNF-AS,FAM120C,PTPRZ1,TUG1,PPP2R3C,CEP97,RALGDS,RAP1GDS1,RASGRF2,RBBP6,GTDC1,RFX4,SEC61A2,KLHDC8A,SPIN3,GLDN,MAP6D1,AP1AR,SOX6,SUPT20H,COPZ1,SH3BGR,KIF21A,HKDC1,SLITRK3,DZIP1,ABLIM3,SLC6A11,ARHGEF40,RIMS1,MAPKBP1,MBD5,CMTR2,SNRPN,TNIK,SOX11,KDM4C,ZC3H13,TSPYL2,RBM26,NFASC,CLASP2,POGZ,SSTR2,ELOVL4,PLCB1,C12orf76,UNC5D,TPCN2,SYNE1,TMEM151B,CRB1,AP4E1,ENHO,TJP1,ACTR6,KCTD2,KAT6B,PIK3R5,RGMB,SMUG1,DCBLD1,TTTY15,FAM155A,LINC00689,FLRT2,BCL2L13,ZNF711,TRIM9,ATP6V0E2,FMN2,GPR158-AS1,SPHK2,ZNF138,ZNF142,REEP1,PLPPR5,DHX33,PRDM2,NT5M,LMAN2L,PPP1R3F,CAB39L,MPPE1,EPM2A,RTN4,TMEM63C,FBXO36,CASC15,ACTR3B,ADAMTSL3,VANGL2,SSPN,FRMD6,SOCS4" MicroRNA hsa-miR-935:mirSVR_highEffct hsa-miR-935:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-92 1.02E-88 9.94E-92 9.16E-91 226 896 "RALGAPA1,ACLY,GALNT13,ADD3,HACE1,OSBPL6,CC2D2A,LRRC7,PCDH10,GPRASP2,SYT13,DPP10,MAP4K3,APAF1,APC,CDC14B,TMEM263,TMEFF1,RGS20,CADPS,STK33,ATP1B3,STX16,ATP2A2,NOL4,SYNJ2,MTMR2,IL33,ZNF555,KALRN,CBR1,KRIT1,MTMR7,TMEM257,SYNGR3,CDC27,LGI1,CFL2,RCBTB2,SRSF11,CHM,LY86,LETMD1,SLC4A8,ABI3BP,FEZ2,CSNK1G3,SIPA1L1,SOCS5,PDE4DIP,PLXNA4,DZIP3,NRSN1,KIAA0586,DBN1,MYEF2,ZC3H11A,ARNT2,DLG2,GRIN3A,RAB39B,DMD,NR1D2,DNAJB6,ABCC5,DNM1L,ABCC9,EBF1,WDPCP,EDNRA,MBNL2,EIF4G2,TENM1,EML1,GPHN,RTN3,ADGRV1,DLC1,SLC9B2,FGF1,FHL1,CAP2,C2orf88,TPK1,KHDRBS3,STAU2,SARAF,MEGF10,GABRB3,CAB39,RAPGEF6,DISC1,MYOZ2,GCNT2,TUBGCP4,SESN1,PCDH17,GGT7,MALT1,COPS8,SPIN1,GLRB,GLUL,PCDH11X,ZNF638,MAP7D2,GPM6A,GRM3,LINC01551,GUCY1B1,HMGB1,GABARAPL2,HTR2A,LRRCC1,LIX1,KCNC1,KCNJ16,KCNQ2,KTN1,INSYN2,PAXBP1,LMO2,NCOA7,SMAD1,GPR155,MAT2A,SHC3,MIA2,SCAMP5,AFDN,MN1,ZNF680,MYO9A,MYT1,NACA,NAP1L1,NAP1L2,P2RY13,NEK1,NF1,CNOT4,GPR88,PAK3,PCDH9,PRTG,ABCB1,FAM218A,A2ML1,XRN1,PCDH18,HMGCLL1,MTRF1L,PURG,SH3KBP1,POU3F2,LRRN3,PRKCZ,GRAMD1C,PRPSAP2,RELN,PTAFR,PTPRB,PEX5,CEP97,FAM184A,RADX,RAVER2,ROBO2,PCMTD2,CCDC102B,FBXW7,PRR5L,ZNF331,RMI1,SH3GL3,NTNG1,SHMT2,FBXO11,FNDC3A,CNKSR2,ZNF365,FAM81A,PPP4R3A,WDR47,LRRC55,RAB3GAP1,CCDC88A,SLC12A2,EFHD1,ATF7IP,ZKSCAN3,RIMS1,MYT1L,DOK5,SP2,CLSTN2,POGZ,LARP4,RGL1,ADHFE1,PRRC2C,PLCB1,C12orf76,UNC5D,MGRN1,ANO4,ACSL6,TRIM2,WDR7,PUM2,THBS4,GZF1,HEY2,TMPO,TP53BP1,TTC3,PLEKHH2,CLDND1,ZNF184,EMSY,VPS35L,MPPE1,GOPC,FBXO36,SSPN,NETO1" MicroRNA hsa-miR-496:mirSVR_highEffct hsa-miR-496:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.95E-92 1.09E-88 1.07E-91 9.83E-91 230 928 "SYS1,ACTN2,RNF150,WDR35,HFM1,BCAR3,ANK3,LCORL,PHF12,RGS20,MARCH3,ASPH,ZBTB10,NCOA1,EIF4G3,ATP2A2,SYNJ1,AP1M1,WASF1,IL33,CA8,CALB1,ZNF555,NFS1,CD86,CDH2,ZMYM4,L3MBTL4,MS4A7,RAB28,NRXN1,NRXN2,QKI,ARHGEF6,CNR1,AKAP6,COL4A5,COL9A1,MYRIP,MFSD4A,SLC35F1,CPS1,CRHBP,CRMP1,CS,CFAP61,ST18,CYBB,ARHGAP32,KATNAL2,RIPOR2,EARS2,LIN54,KIAA0586,MAML1,IP6K1,PABPC5,PITPNC1,ZNF804A,KIAA0319,RABGAP1L,DNM1,DTNA,DYRK1A,EDIL3,EDN3,KLHL5,FSD1L,RBM12,MRO,KMT5B,STARD3NL,CALCRL,DCTN4,ENPP6,RTN3,SIRPB1,FCGR1A,GORAB,SUCO,CAP2,FLT1,JKAMP,SARAF,TBR1,TVP23A,PHYHIPL,ARPP21,GART,ADAM28,MALT1,TCERG1,MSL3,ZNF782,WDFY3-AS2,ADGRA3,CNDP1,GPR34,EML4,TMEM121B,GRIA4,AP4S1,IRAK3,NXPH2,ELOVL5,HMGB1,HMGCR,MYLK2,IL6R,ITGAV,METTL21A,LYPLAL1,MATN3,MBNL1,ADAM22,P2RY13,NCAM2,NEUROD1,NFE2L2,NOVA1,HCN1,NTRK2,OPHN1,OXTR,PAH,PAX6,PBX1,PCDH9,PCSK1,PDE1A,PDGFRA,PIK3R1,GPSM2,HMGCLL1,PURG,LRP12,TATDN3,PRKACB,VPS13C,TMEM260,PTPRE,STRC,CEP97,TMEM255A,RAD51D,FAT4,RET,GTDC1,RNF220,RPE,GLDN,LRRK2,TMEM156,SCN3A,SCP2,SLC30A10,SGK1,SH3BGR,KIF21A,ITSN1,ARX,CPEB3,MAGI3,FHOD3,ANKRD6,ZNF365,SLC1A6,FAM81A,BTBD3,KANSL3,SEPHS1,SLC12A2,SLC14A1,ELMO2,CPEB4,SMARCE1,LIMCH1,MBD5,SNRPN,TMCC1,MYT1L,ATP10B,TROVE2,SMOC1,SS18,ELOVL4,FAM168A,SYNE2,PLCB1,COBL,TACC1,ANKRD12,FAM208A,FBXW11,RPGRIP1L,WASHC4,WDR7,DOCK9,GPRIN3,PMS2CL,C18orf54,AP4E1,ZMAT3,SLC44A1,ERCC6L2,BEX4,PRRT1,TPM1,TMEFF2,UBE3A,FLRT2,MTCH1,TOM1L2,MEAF6,BEST1,TBC1D15,P2RY12,GPR158-AS1,FSTL5,SMARCAD1,WNK1,PRTFDC1,ADAMTS9,HPS4,FAM47E,AMN1,PHTF2,ZNF248,FRMD6,SLC4A10" MicroRNA hsa-miR-33b:mirSVR_highEffct hsa-miR-33b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.95E-92 1.10E-88 1.07E-91 9.85E-91 222 865 "ABHD6,TKTL1,SLC25A25,FMNL2,SLC12A5,CDC7,BEND6,SORCS2,CC2D2A,UNC79,CDC42BPA,DPP10,SEMA7A,PHF12,MAGEE2,TNRC6C,TMEM263,SPTBN4,ZNF583,SLC2A11,B3GALT2,ADAM23,BACH1,ADGRB3,CDK5R1,THSD7A,KALRN,PTBP2,USP6,AIFM1,CDH18,LGI1,CHN2,CLCN3,NRXN2,QKI,MAP4K4,IQCK,ARMC8,AKAP6,AKAP12,CS,RGS6,SEC24C,MICAL2,VCAN,SLITRK5,PHF14,ST18,ZFYVE16,ZEB2,MYEF2,PLPPR4,WDR20,RCAN1,ARRDC4,GOLT1B,E2F5,EBF1,EDNRB,FCF1,SEMA3D,RBM12,EGFR,C8orf37,CALCRL,EN2,VPS13B,ANKMY1,EYA1,CLVS1,ABCA8,RPS6KC1,FER,OLFM1,FGF14,SORBS1,SMC2,ATP6V1H,CELF1,ZNF512,DKK3,HBS1L,SALL3,ERAP1,LRRC37A6P,MYOZ2,SULT1C4,MSTN,GGTA1P,ZNF638,HTATSF1,GPD2,STON1,GRIK2,PRDM5,ZNF496,LINC01551,ADAMTS6,MAP4K5,WIF1,RASSF8,HAS2,ZHX1,LINC01102,BACH2,HMGCR,HNMT,C9orf129,LRRTM3,METTL21A,KCNA4,KCND2,KCNJ3,LIG4,PAXBP1,ARHGAP12,LSS,MARK1,MATN3,MBNL1,MEIS2,ERICH3,MSR1,CTNNA3,NAP1L2,NAP1L3,NCAM1,NDUFA5,CNOT4,NPY,GPR88,SNTG1,PDE3B,PDE4D,ENPP2,GDAP1L1,NOMO2,PLIN1,PCDH18,MTRF1L,PDZRN4,TRHDE,ING3,PPM1B,PPP3CA,PPP3CB,MASP1,MDGA2,CNTLN,PTHLH,PXK,TMEM260,PTPN13,PTPRB,TTC13,ZNF615,MARCH1,ARID4A,RADX,ZDHHC14,RDX,SLC6A15,RGS12,NUDT11,CARF,RPE,FBXW7,TRAPPC13,SCN3A,SCN8A,LINC00461,SH3GL2,ARX,CPEB3,SLITRK3,ZNF365,SLC1A6,FAM81A,WDR47,SLC14A1,SLCO1A2,SORCS3,SNRPN,ENKUR,MYCBP2,KIF1B,IQSEC2,RBM26,COLGALT2,EPB41L3,SYT11,VPS13A,AGTPBP1,KLHL4,SATB2,ZEB1,WASHC4,WDR7,RALYL,ZFPM2,CRB1,ITGB3BP,CSMD1,TPM3,KCNE5,CADM1,UGT8,TBC1D15,XRCC4,ZNF711,TRIM9,LAMP5,EMSY,PRDM2,NAV3,WNK2,SLC17A6,GOPC,FAM13C,SLC4A10,CPNE4" MicroRNA hsa-miR-663b:mirSVR_lowEffct hsa-miR-663b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.31E-92 1.30E-88 1.26E-91 1.16E-90 264 1213 "ACADM,ASIC1,NBAT1,GPRIN1,SLC25A25,NDRG2,GALNT16,PSMG3-AS1,ADD1,PNMA8B,ADORA1,UNC5A,PWWP2A,KCTD16,SORCS2,ADGRF5,GOLGA7B,ZNF687,AMT,PKP4,APBA2,DGKD,FAM131A,PPFIA3,USP37,SHROOM2,CDC14B,CDK10,SEMA4G,PDXK,SPTBN4,ARHGDIA,LINC00173,RASL11B,ATP2B2,ADAM15,NRP2,ARHGEF7,CACNA1I,BAIAP3,CACNA1A,CABP7,KALRN,HAP1,SPAG9,CBR1,CBS,SYNGR3,CDC27,MAGI1,CRLF1,CFL2,ASIC3,CHRNA4,LSMEM2,PPT2,FADS2,PCYT1B,MFSD4A,SH2B1,MICAL2,RASGEF1C,CTH,RUBCN,SEC14L5,BOC,KATNAL2,ZNF337,INTS1,TIAM2,RUSC2,RHOBTB1,SRGAP3,FAM107B,DLG4,DMPK,HS3ST2,ATN1,USH1C,HIPK3,CNNM1,HEYL,SUGP2,EBI3,IRAK4,OLIG2,EPB41L1,STX2,EFS,SPEG,ETV1,PTK2B,FCGRT,OLFM1,FGF11,CAP2,IP6K2,FOXO3,EVL,PSD2,FLYWCH1,C2orf88,WDR83,KBTBD12,B3GAT1,ABLIM2,SDCBP2,PHYHIPL,NEURL4,INPP5K,GATM,TUBA8,C1QL1,DHRS4,GLYR1,MSL3,KCNMB4,GNAS,FERMT2,GRB10,RFFL,GRM2,GPR45,VSIG4,SYNPO,HMGCL,HNF4G,C9orf129,OPALIN,LRRC75A,SHISA6,ICA1,IL6R,SCRT2,KCNB1,KCND1,KCNK2,KCNMA1,TTYH2,MAP4,MAP6,IL17D,CCDC80,MYO7A,MYT1,NCAM1,NEUROD1,NHLH1,VWA2,NPTX1,OPHN1,OPRL1,ZNF713,PDE1A,PDE4B,PFKFB2,ZNF655,ZFYVE21,ST8SIA5,PLIN1,SMIM7,PLXNB1,PNMA3,C11orf49,MAPKAP1,SEPT4,DRAM2,TMEM235,PPP2R2C,PRKAB2,PRKCZ,SLC26A11,GRAMD1C,HYDIN,SLC22A23,CYBC1,SNRK,TMEM104,PLPPR1,TMEM260,PTPRG,ZNF615,USP47,FAM66C,RASGRF1,MSANTD2,DPF2,GTDC1,UBR7,RGS3,PRIMA1,SEC61A2,RIC8B,CARF,RORB,EPHA10,SCN2B,SCN4B,FERMT1,MAGI3,FNDC3A,BTBD3,LRRC55,ARHGEF40,CCDC88A,SLC9A5,SHANK2,TMEM132D,ELMO2,ARFGAP1,KIF13A,FAM126B,UNC80,TRERF1,TNIK,SPTAN1,IQSEC2,TSPYL2,STX1A,KLHL7,ZC3H4,RHBDL3,TMEM150C,KAZN,ALG1,AGTPBP1,VWA3A,NEU4,CUX2,TCF7L2,WDR7,AZIN2,SYNE1,PHF24,TMEM151B,PUM2,AHCYL2,RNF216P1,ENHO,TK2,CABIN1,C9orf85,ZNF346,SYNPO2,HIRA,BCL2L13,CCDC14,RICTOR,GUSBP1,ZNF74,CELF4,AMZ1,TMEM198,SPIRE1,DHX33,XKR7,SEMA3B,PLSCR4,ST7,CASC15,ZNF248,TTC7A,PIANP,FAM181A" MicroRNA "TGCTGCT,MIR-15B:MSigDB" "TGCTGCT,MIR-15B:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA "TGCTGCT,MIR-16:MSigDB" "TGCTGCT,MIR-16:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA "TGCTGCT,MIR-15A:MSigDB" "TGCTGCT,MIR-15A:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA "TGCTGCT,MIR-497:MSigDB" "TGCTGCT,MIR-497:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA "TGCTGCT,MIR-424:MSigDB" "TGCTGCT,MIR-424:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA "TGCTGCT,MIR-195:MSigDB" "TGCTGCT,MIR-195:MSigDB" MSigDB 2.40E-92 1.35E-88 1.31E-91 1.20E-90 181 569 "ARID1A,SLITRK1,AXIN2,PLEKHH1,ADRB2,AP2A1,CASKIN1,ARHGAP20,OGT,ANK2,CNIH2,APP,ARHGAP5,ARHGDIA,STK33,ASPH,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B2,ADGRB1,BCL2L2,DCAF5,NRP2,CDK5R1,SYNJ1,BTRC,CALM1,KALRN,CAPN3,MAP7,RUNX1T1,CDC42,DCLK1,SRSF11,SOCS6,QKI,SLC4A7,TBPL1,CLOCK,LRIG1,PHF19,KCTD8,ARMCX2,COPS7A,POM121,DYNC1I1,CPEB2,DMTF1,DRD1,ABCC5,TSPAN5,SEMA3D,PHF20L1,PLEKHA1,DMTN,ANKRD13B,RASL12,EYA1,EZH1,ACSL4,SPSB4,CAMSAP1,SUCO,PDLIM5,ARFGAP2,NSG1,TPPP3,GABBR1,CAB39,ARPP21,SESN1,PCDH17,GHR,FERMT2,TMEM121B,GRIN1,GRM7,CLASRP,IL1RAPL1,HAS2,ZHX1,BACH2,KIF5A,SFXN5,ARHGAP12,MAP4,MBD1,LRP1B,ZC3H12B,OMG,PCDH9,PCMT1,CAMKV,PIK3R1,RETREG2,EPB41L4B,NXPH1,POU3F2,FSD1,LRRN3,PPP2R5C,PPP3CB,RASGEF1B,MAPK3,RELN,SIDT1,DEF8,SNRK,PTHLH,PEX5,TMEM255A,RBBP6,RET,ZNF532,ARMC5,FBXW7,SYNDIG1,SEMA6D,ATXN2,SCN4B,MRAS,HSPA4L,SGK1,KIF21A,SH3GL2,PPM1E,FRMPD1,CPEB3,NLGN1,FAM81A,WDR47,LRRC55,KBTBD4,SLC12A2,ELMO2,TMCC1,SON,WDTC1,MYT1L,ZHX3,KIF1B,TSPYL2,STX1A,STXBP1,GSE1,ACSBG1,VAMP1,ARHGEF9,SYPL1,C12orf76,SATB2,TRIM2,SYNE1,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,TGFBR3,ARL10,TRPM2,HIRA,VAV2,WNT7A,KLC2,RICTOR,SLC13A3,ZIC1,CSDE1,STOX2,LMAN2L,KCNAB1,PCBP4,PAK5,ADAMTSL3" MicroRNA hsa-miR-324-5p:mirSVR_lowEffct hsa-miR-324-5p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.47E-92 1.39E-88 1.34E-91 1.24E-90 247 1068 "KCNH8,ASIC1,ARID1A,CCDC85A,ADORA3,KIDINS220,AP2A1,HACE1,PLA2G6,ZNF578,TAOK1,SMIM17,MARCH4,PCDH10,GPRASP2,LRCH2,ANK3,GPAM,SFMBT2,SEMA4G,TMEM263,SPTBN4,CDK13,ZBTB10,ATP1B3,ALDH7A1,ADAM23,TTLL9,AZGP1,ADGRB1,LINC00847,KSR1,MTMR3,CFAP410,CA12,THSD7A,CANX,CAST,RUNX1T1,USP2,REPS2,LRRFIP1,PPT2,QKI,HOMER3,IGLON5,SLC4A8,IFFO1,SMARCAL1,NCOR1,CRYM,SNCAIP,SEC24C,NCAN,KIAA0040,ERC2,CFAP61,NRSN1,GPSM1,FAM131B,KIAA0408,ARHGAP32,ZNF337,DGKB,SIRPA,ZEB2,FBXL5,TMEM130,ALKBH8,SRGAP3,FAM107B,DLG4,GRIN3A,RPS6KL1,SLC29A4,CDON,SLC12A6,ACOT8,DTNA,ABCC9,SNX29,HIPK3,FCF1,C3orf18,RABEPK,VPS26C,RASL12,EZH1,ARMCX1,TMEM132C,CORO2B,ST3GAL6,STRADA,SUCO,MEX3B,SPECC1,CAMKK2,NSG1,SARAF,TBR1,NRG3,GABRA2,GALR1,TMEM8B,ALDH1L1,GGT7,GJB1,RAB30,GLRB,PCDH11X,HTATSF1,GNAS,GNG4,ADGRA3,GPD2,CECR2,GRM7,CIT,MFSD2A,ATOH8,IRAK3,HAS2,GPR45,DDX19B,SYNPO,CELF5,IRF8,RBPJ,USP54,ZNF678,KCNJ4,KHK,LINC00634,KLRC2,CYP27C1,KTN1,HECTD2,FGFBP3,MAP2,PPM1L,MOBP,DBNL,MSRA,RTL5,ZNF862,NAP1L1,NAP1L2,FXYD6,P2RY13,NBL1,NDP,DNHD1,PCBP3,NTRK3,P2RX7,PBX1,PCMT1,CDK18,PDE1A,PDE4D,GNG2,PFKFB4,NLGN3,PIK3C2A,PIK3CD,XRN1,FAM216A,SMIM7,PDZRN4,EPB41L4B,POU3F2,TMEM235,NKAIN4,PRKAB2,DCHS2,WBP1L,SIDT1,GON4L,PIGG,PID1,SLC25A48,RAD17,SH3TC2,ZNF493,ZYG11B,RFX4,KCTD17,NCBP3,FAM192A,DGLUCY,AMER2,ATXN7,HOGA1,MRAS,KIF16B,DOCK10,HKDC1,SLA,SLC6A7,SLC6A8,RAB3GAP1,ARHGEF40,SIRT2,SLC9A5,IFT122,INAVA,MBD5,WDTC1,SOX1,LHFPL4,GANAB,MLC1,SYNE2,KAZN,SEMA4A,IQCE,ANO4,TCF4,TCF7L2,ZEB1,CLASP1,NAT16,FAM189A1,PUM2,FBXL16,THRA,TJP1,ZFP91,ERCC6L2,HEY2,RIMBP2,SYNPO2,AMACR,EIF4ENIF1,BCL2L13,BEST1,WIPF1,PORCN,AGMO,SPHK2,PRDM2,PRDM8,CIAPIN1,ITM2C,PARP11,EPM2A,NLRP3" MicroRNA hsa-miR-34c-3p:mirSVR_highEffct hsa-miR-34c-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.17E-92 1.78E-88 1.72E-91 1.59E-90 218 836 "KCNH8,ARID1A,SLC12A5,PWWP2A,MTUS1,KCTD16,RTL9,TAOK1,ABCD2,MARCH4,OGT,PHF12,APC,ALS2,MIER1,RGS20,ATP2B1,ADAM23,DST,SYNJ1,CACNA1G,CACNA1D,CALB1,ISPD,RUNX1T1,KRIT1,CDC27,CCPG1,CFL2,SYNPR,JAM2,TMEM155,ARMC8,AKAP6,HS3ST5,CHD1L,SLC35F1,FAM171B,RNF14,TRIM69,SNCAIP,ATRNL1,NRSN1,ST18,USP6NL,CCDC144A,CYBB,DOCK4,GAPVD1,LIN54,DGKB,DCT,MYEF2,CEP170,FBXO25,ALKBH8,RHOBTB1,SRGAP3,EXOG,CPEB2,DMTF1,DPP6,ABI1,RCAN1,FAM135B,HIPK3,RASGRP1,OPTN,PHF20L1,MBNL2,TENM1,ELAVL2,PLEKHA1,RCAN2,RTN3,ADGRV1,ABCA8,ZNF585B,DLC1,FER,FGF14,FHL1,SUCO,MEX3B,FLT1,PSD2,PDLIM5,FAM49B,NPTN,ATP6V1H,ERGIC3,CELF1,GABBR1,GABRA2,CAB39,GAD1,HBS1L,NCKAP1,MTHFD2,MYOZ2,TUBGCP4,ARFIP1,WASHC2A,PCDH17,BRD8,COPS8,GPM6A,GPM6B,GRIK2,GRM3,KIF3A,MAP4K5,HAS2,ZHX1,FRMD3,MIER3,HMGCL,DHX35,MSL1,KIF2A,LAMP2,MAP2,MARK1,LDLRAD3,AFDN,MOBP,MRPL42,NCAM1,DNHD1,LOC100128398,GPR137C,PDE4D,PDGFRA,OLA1,PLCL1,TRHDE,STRN3,SCHIP1,PRRX1,SDK2,KANSL1,PRKACB,EPDR1,PSMD13,CNTLN,ELOVL2,ZNF615,RBBP8,RFX4,RNASEL,RPRD1A,SETD5,EXD2,ROBO1,RPE,ARMH4,ADAL,LINC00461,PEAR1,MRAS,SUPT20H,PUF60,NLGN4Y,SCG5,NTNG1,MAGI3,CHD9,FNDC3A,SLITRK3,ANKRD6,FAM81A,PREX2,SLC8A1,CCDC88A,KBTBD4,BTBD7,RCOR3,SNCA,MBD5,FAM126B,SON,MYT1L,SOX5,MYCBP2,ZC3H13,ARHGEF9,SYPL1,SYT1,FAM208A,ADGRL3,EHBP1,ACSL6,TCF7L2,PCDHB3,FRYL,SIRT1,AKTIP,HEY2,TMOD1,PIK3R5,NPL,TRIO,TTC3,CLHC1,CADM1,UBE3A,DNAJC12,MEAF6,ZNF711,ZNF189,LAMP5,UPF3A,ADAMTS9,TMEM163,CAB39L,PDSS2,KAT6A,IFT88" MicroRNA hsa-miR-137:PITA hsa-miR-137:PITA_TOP PITA 3.75E-92 2.11E-88 2.04E-91 1.88E-90 173 518 "ABHD6,FMNL2,TMEM132B,RNF150,NLGN4X,INTS2,OSBPL8,C1QTNF3,UNC79,TRMT9B,PITPNM2,SHROOM2,ARHGAP5,CADPS,ARHGEF7,CACNA1G,NIPA1,BSN,CACNB2,DCLK1,FOXN3,SOCS6,CHM,NRXN3,FAM19A5,QKI,COL4A5,SLC4A7,ABI3BP,BAG4,ZNF385A,PNKD,CREB5,RGS6,CSNK1G3,RIMS4,ST18,ZFYVE16,RIMS3,MAML1,DGKG,YTHDC1,ZC3H11A,RHOBTB1,SV2A,SRGAP3,SLC12A6,DYRK1A,EDIL3,FRY,EFNA3,RBM12,MBNL2,ELAVL3,EIF1,RCAN2,KCNMB2,SLC43A2,ERBB4,FGF11,PRKAG2,NBEA,MEGF11,AHCYL1,GPR162,PPARGC1A,GLS,LUZP2,GPD2,GPR26,PTPN5,WIF1,KLF12,BACH2,MIER3,HLF,HAPLN2,IL6R,SCRT2,KCNA1,KCNA2,KCND1,KIT,LRP1B,MEF2C,MITF,MSI1,RCOR2,NEFH,NEUROD1,NEUROD2,NF1,NFIX,NOVA1,GPR88,GPR137C,CNTN3,PDE4D,PDE1B,GPR85,TMOD2,HMGCLL1,LRP12,FAT3,MED1,LRRN3,PPP5C,PKN2,DIRAS2,WBP1L,SNRK,PTN,PTPRB,NKAIN1,OXR1,MSANTD2,SLC6A15,ZMAT4,MORC4,RIC8B,RAVER2,SYNDIG1,STX1B,ATXN1,SCN2A,SOX6,NLGN4Y,PPM1E,CHD9,ST3GAL3,PPP4R3A,SLC6A8,SLC6A9,SLC8A1,SLC12A2,FAM126B,SOX11,NFASC,NKAIN2,SS18,ERBIN,NXT2,STAC2,SEPT3,PLCB1,SYT1,ANKRD12,ACSL6,TCF4,SATB2,RPGRIP1L,TCF12,AHCYL2,ZFPM2,AP4E1,AKTIP,TJP1,HEY2,TRPS1,FNDC5,TSN,UBE2H,SLAIN1,BCL2L13,MGAT5B,WNT7A,SLC30A4,EMSY,SLC17A6,RGS7BP,HNRNPA3,PHTF2,MSRB3" MicroRNA hsa-miR-196a*:mirSVR_highEffct hsa-miR-196a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.84E-92 2.72E-88 2.63E-91 2.42E-90 227 908 "RALGAPA1,ARID1A,NDRG2,ADCY6,ADD1,ERMN,ADORA3,RNF150,RTL9,HACE1,OSBPL1A,CC2D2A,PDZD4,ANK2,PKP4,APC,MIER1,ZBTB10,DPY19L3,NRP2,JAZF1,AP1M1,CA8,CACNB2,CACNB4,KALRN,CDC27,DCLK1,ZMYM4,MAGI1,CFL2,SOCS6,CHI3L2,NRXN1,HECTD1,CNTFR,AKAP6,ABI3BP,ACBD5,IGDCC3,HS3ST5,FAM171B,PREPL,HAPLN1,AATK,NRSN1,RIMS2,USP6NL,HDAC9,FRMPD4,TOMM20,ZEB2,HP1BP3,RHOBTB1,PLPPR4,AK5,RABGAP1L,KIF19,DLG2,DYNC1I1,ATN1,DNAJB6,KRBA2,HIPK3,FCF1,FSD1L,PHF20L1,SUGP2,ABI2,EGR3,EIF4G2,ELAVL4,C8orf37,DCTN4,LRRC17,KCNMB2,SRRM1,NCALD,FAM198B,WAC,PPP1R1B,CAMSAP1,FHL1,FOXF2,IP6K2,SYNCRIP,FOXO3,SLC37A3,C2orf88,TPK1,STAU2,AP4B1,STAG2,DKK3,GABRB1,ARPP21,NCKAP1,GPR162,BRD8,TCERG1,TNRC6A,GPM6B,ATF7,TDRKH,GPR12,CECR2,PCLO,GRIK2,ADAMTS13,GRM5,CELF3,PADI2,ELOVL5,HNMT,IRF8,IGFBP1,ZNF678,LRRTM3,KCNJ16,KCNMA1,KIF5A,KIT,CYP27C1,PACRG,PIK3AP1,GPR155,ZNF667-AS1,LDLRAD3,MEIS2,ERICH3,RSPO2,PABPC1L2A,NDP,NDUFA5,NEUROD1,NF1,NKX2-2,NPPA,NRCAM,ENPP2,GPR85,NALCN,SMIM7,PMP2,PPM1B,PPP2R5E,PPP3CB,EPDR1,SYTL2,SIDT1,PTHLH,RASGRF2,MSANTD2,CRTAC1,PRRT2,ERI2,FIGN,RGS12,SEC61A2,SLC25A36,PBRM1,RPRD1A,CARF,ELP2,PCMTD2,ARMH4,ATAT1,KCNIP1,ZNF354C,ZNF331,LRRTM4,SCP2,FNIP1,ASRGL1,FAM102A,CHD9,SEC31A,FAM81A,CCDC88A,NAPB,TET1,ZFP1,SORCS3,SMARCE1,SNCA,TEX2,NPAS3,ST5,SEPT8,TTBK2,DIP2A,FGD4,SYP,SYPL1,AGTPBP1,ATMIN,EHBP1,ZEB1,TCF12,TMEM151B,TF,NACC2,CSMD1,TRIO,RUNDC3B,ZMYND8,NTSR2,TSN,ANKRD20A2,TSC1,TMEFF2,UBE3A,PLEKHH2,LAT2,ZBTB14,KCNT2,TCEAL7,REEP1,SPIRE1,STMN4,TMEM178A,AMN1,JMJD1C,NLRP3,MSRB3,PIANP,SLC4A10" MicroRNA hsa-miR-214*:mirSVR_lowEffct hsa-miR-214*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.67E-92 3.18E-88 3.07E-91 2.83E-90 277 1333 "DGCR6,SYN3,ASIC1,ACLY,KDM5D,UNC5A,PWWP2A,SNX32,KIAA1324,WDR35,SRPX,ZNF687,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,ALS2,CDK10,SEMA4G,PRX,SPTBN4,DACT3,ASTN1,SLC2A11,DPY19L3,RGS9,NRP2,BID,CFLAR,LINC00906,BTRC,CA12,KALRN,VXN,SYT6,CCNH,USP6,CD38,CDC42,LRRFIP1,EVI5L,TIGD7,CHM,MS4A7,CHRNB2,TAOK2,LSMEM2,NRXN3,MAP4K4,CNR1,PICK1,LETMD1,ABI3BP,ZNF521,C2CD2,AKAP12,CRY2,C1QL2,SNCAIP,ARHGEF10,VAC14-AS1,PLXNA4,UBXN2A,ARHGEF4,CTNND2,RIMS2,GPSM1,DCAF4,BOC,KATNAL2,GAPVD1,TOX,ZFYVE16,CENPL,LONRF1,DGKG,TOMM20,GIT2,CNIH3,MAGI2,TMEM130,RHOBTB1,SNAP91,SV2B,AK5,SGSM2,KIF19,DLG2,GRIN3A,DMPK,CD99L2,DSCAM,DTNA,DTNB,DYRK1A,HIPK3,EFNB3,MBNL2,TNK2,ZNF549,KATNAL1,ECSIT,RACK1,TOMM40L,FECH,SLC37A3,EFCAB2,RASL10A,NSG2,TVP23A,ZNF512,GABBR1,BRPF3,ARPP21,DISC1,STARD10,CPLX1,SULT1C4,CYP46A1,RAB30,GLS,PCDH11X,GPD2,PCLO,GRB10,PLCD4,GRID1,RFFL,GRM2,MAP4K5,TMEM179,CELF3,MAEL,NXPH2,PTGDR2,MAN1B1,AGBL5,CPT1C,LRRC75A,MYLK2,SOWAHA,KIAA1755,IL11RA,INSM1,STXBP5,LIMS1,ARHGAP12,NCOA7,ASPRV1,MID1,COMMD5,N6AMT1,CTNNA3,MX1,LAYN,ZNF862,NDUFA5,CCDC13,NELL2,CNOT4,NOVA1,SMIM11A,ODF2,GLIPR1L2,PDCD2,PDE3B,SSH1,A2ML1,CCSER2,PKD1,GPSM2,ANKRD16,PMP2,CDIP1,PRRX1,SEPT4,PACSIN1,MINDY2,PRKACB,CEP41,PRKCZ,GRAMD1C,MASP1,WBP1L,SIDT1,MDGA2,WDR25,TMEM260,PTPRG,PTPRO,PEX2,TUG1,RAB3IL1,ZNF493,RET,GTDC1,RGS12,PBRM1,ZNF532,ALG9,HSD11B1L,ATAT1,RXRG,ATXN2,SCP2,TRIM46,CASC3,GALNT10,SGK1,ITSN1,PPM1E,FRMPD1,KIF16B,DZIP1,SLA,SLC1A6,DHX30,SLC9A5,CDK5RAP2,TTC17,RIMS1,SNAP25,SNRPN,FAM126B,PDZRN3,CLUAP1,GLT8D1,CAND2,PEG10,NFASC,LHPP,CLSTN2,SS18,PHLDB1,FAM168A,COBL,FAM208A,ADGRL3,WWC1,ANO4,TCF4,TRIM2,AZIN2,DOCK9,TMEM151B,RALYL,AKNA,USP32P1,TNS2,HIF3A,ATP13A2,CDH22,GALNT17,BHLHB9,ERCC6L2,KCTD2,RBFOX2,TPM3,ZNF384,ZNF346,ZMYND8,TUBB1,MEAF6,CCDC14,GUSBP1,SF1,TRIM9,ZBTB16,EML6,PCBP1-AS1,EMSY,PRDM2,STOX2,CAB39L,RGS7BP,UBE3B,CAMK1G,TRAM2-AS1" MicroRNA hsa-miR-4315:mirSVR_lowEffct hsa-miR-4315:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.43E-92 4.17E-88 4.02E-91 3.70E-90 216 824 "CSMD2,SLITRK1,ADD3,KIAA1211,HFM1,TAOK1,ADGRF5,PCDH10,GOLGA7B,BEGAIN,PHF12,TNRC6C,PPFIA3,CAPRIN2,ZNF583,ADGRB3,LINC00847,BCL2L2,NRP2,DST,BTK,WASF1,CFAP410,CACNB2,CAST,LGI1,MS4A7,KMT2C,NRXN3,TMEM184B,FAM149A,COL9A1,LETMD1,COL11A2,ABI3BP,CREM,SH2B1,CRMP1,NCOR2,SNCAIP,CSF2RA,ATRNL1,SOCS5,PDE4DIP,PNPLA8,CTNND2,ZSCAN23,SEC14L5,GAPVD1,FRMPD4,HDAC4,DGKB,CTIF,DBN1,DGCR5,ZEB2,TIAM2,SV2B,SPOCK3,RABGAP1L,DMD,RPS6KL1,DYNC1I1,CASP8AP2,PDCD6IP,RCAN1,MAMLD1,GOLT1B,MRO,PLXNC1,COPS4,EML1,LRRC17,GPHN,SRRM1,EXTL2,WAC,RPS6KC1,CACNG2,TBC1D16,CEP78,FCGR3A,GORAB,POLK,SUCO,SGIP1,SLC37A3,PDLIM5,STAG2,GALC,MTHFD2,KIAA1841,ADAM28,PPARGC1A,GK,TCERG1,COPS8,RAB30,GLRB,LNX1,WDFY3-AS2,ADGRA3,PCLO,GRIA2,GRIA4,GRIN1,LINC00839,HNMT,IGFBP1,IL12A,INSM1,TUBB2B,ZNF385B,LRRTM1,KCNC1,KCNK1,MEIS2,AFDN,WDR49,LAYN,NCAM1,NEFM,NEK1,NEUROD1,CNOT4,NOVA2,NPPA,SMIM11A,NTRK2,NUCB2,OMG,PAK3,PBX1,PCSK5,GPR85,FAM218A,NXPH1,LRRN3,PRKACB,MAPK10,PRPSAP2,WDR25,PXK,TTC13,CEP97,OXR1,FEZF2,SLC6A15,FIGN,ZFHX4,UEVLD,PAQR6,WLS,TRAPPC13,FAM192A,SALL1,SCN8A,ELMOD1,SFPQ,SGK1,SCG5,DOCK10,FHOD3,CNKSR2,WDR37,CPEB4,COA1,RCOR3,KDM4B,PDZD2,BDP1,INKA2,VPS13A,NUDT10,FNDC9,POPDC3,MCF2L,TAF9,TBX15,TCF7L2,TRIM2,SYNE1,PHF24,FRYL,PMS2CL,SLC44A1,HEY2,RIMBP2,KCTD2,PARD3,STXBP4,DCBLD1,TSC1,LRTM2,TMEFF2,UGT8,ZNF709,VLDLR,WRN,XPO1,PCDH20,ZFP37,KCNT2,ATP6V0E2,CELF4,DPYSL5,EMSY,PRDM2,STOX2,TMEM178A,CAB39L,FAM13C,TMEM63C,SSPN,FXR1,SLC4A10" MicroRNA hsa-miR-629*:mirSVR_highEffct hsa-miR-629*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.44E-92 4.18E-88 4.02E-91 3.70E-90 269 1263 "KCNH8,ACADM,CLK4,ARID1A,KLHL32,GALNT13,ERMN,PWWP2A,BEND6,NLGN4X,RTL9,KIAA1324,ADGRF5,ALCAM,FAM135A,ZNF687,CDC42BPA,DPP10,FGD2,SUGT1P4-STRA6LP-CCDC180,EPB41L5,GPAM,TNRC6C,SHROOM2,NUMB,CCAR2,TMEM108,ATP2B1,ZNF582,NOL4,BACH1,CACNA1G,CACNA1A,CABP7,RUNX1T1,USP6,MTMR7,CD86,MYOM2,CDC27,CDH2,ZMYM4,CDH18,LARGE1,RCBTB2,LSMEM2,QKI,LY86,TMEM155,SUMF2,LETMD1,ZFP28,CHD1L,HAPLN1,RGS6,ARHGEF10,SUSD5,PDE4DIP,RIMS2,USP6NL,ECE2,KATNAL2,LONRF1,ARMCX4,SPATA2,ZEB2,FBXL5,SMG7,HS3ST2,DMTF1,DYRK1A,EBF1,USH1C,EDN1,KLHL5,FAM13A,PHF20L1,EGFR,MBNL2,EIF5,COPS4,ELN,OLIG2,EPHB1,RABEPK,SRRM1,DENND4A,CDKL3,ABCA8,ACSL4,TOMM40L,FCGRT,PRKAG2,CAMSAP1,SUCO,HPCAL4,FOXG1,SEC23B,ATP13A4,FLT1,C2orf88,SPECC1,NPTN,ATP6V1H,CELF1,DACH2,NRG3,ABLIM2,OGA,GABRB3,RAPGEF6,ARPP21,ERAP1,ZNF559,ATP8A2,NEU3,AHDC1,LYVE1,GLS,PCDH11X,ZNF638,GOLGB1,RFFL,ADAMTS13,PSIP1,RASSF8,USP51,NEGR1,C5orf24,ZIC5,INSM1,KCNJ3,CREG2,IPO5,STMN1,SMAD1,PIK3AP1,LOC100128239,MBNL1,MDM4,MEIS1,SRSF12,AFDN,ZNF680,COL28A1,LYRM9,MYO9A,FXYD6,NEFM,NEFH,CNOT4,NRCAM,OXTR,PBX1,PCSK1,PDYN,GNG2,CDK14,NLGN3,ZNF655,RETREG1,XRN1,FAM216A,ZNF426,POU3F2,PPM1B,PRKACB,PKN2,DCHS2,VPS13C,LAMA1,WDR25,PTHLH,PTK2,EML5,PTPRH,ZNF844,CEP97,SLC6A15,ZYG11B,RET,RFX4,RGS3,EXD2,CARF,ROBO2,ZC3H14,ATP8B4,ABCA11P,KCNIP2,ZNF331,ATXN7,SCP2,SLC30A10,ZFP2,CASC3,COPZ1,ZFP30,ITSN1,FAM102A,ST6GAL1,CNKSR2,PAAF1,SLA,ZNF365,RPH3A,SIRT2,SLC9A5,SLC14A1,SORCS3,SNRPN,UNC80,SOX2,SOX3,ZSWIM8,EMC1,ERC1,PEG10,RBM26,TAB2,SSTR2,EPB41L3,TTBK2,FGD4,SYPL1,POPDC3,ANKRD12,FAM208A,KLHL4,TBX15,VWA3A,WSCD1,SATB2,ZEB1,TCF12,WDR7,NAT16,FRYL,FAM200B,GPR161,AKTIP,TIE1,TIMP4,DDHD1,TLR4,HEY2,TMPO,TPM1,NPL,TPM3,TRPS1,ZMYND8,DCBLD1,UBE3A,AMOT,GORASP1,DNAJC12,OSBP2,ZNF781,LGI4,ZNF711,ZNF708,ZNF70,FMN2,CELF4,ZBTB16,FIP1L1,AMN1,SLC4A10" MicroRNA hsa-miR-520f:mirSVR_highEffct hsa-miR-520f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.15E-92 4.58E-88 4.40E-91 4.06E-90 266 1237 "KCNH8,SLITRK1,ERMN,MTUS1,HECW2,AK2,HFM1,ZFAT,ANK1,ANK2,PHF12,EPB41L5,API5,APP,AQP4,MIER1,TMEM263,RASL11B,TMEM108,DPY19L3,BACH1,SEC11C,CFLAR,ST3GAL5,MTMR3,JAZF1,WASF1,CALB2,PTBP2,CANX,VXN,PRC1,METTL6,CBFA2T2,TMEM257,CDC25B,CDH2,LGI1,MAGI1,CLGN,CFL2,RCBTB2,ABCG2,MAP4K4,ARMC8,AKAP6,LETMD1,AKAP5,ACBD5,IGDCC3,CNRIP1,ZNF385A,ATRNL1,SOCS5,PHF14,GREB1,USP6NL,CCDC144A,FRMPD4,TOX,DBI,YTHDC1,ZNF804A,ZEB2,HP1BP3,ZC3H11A,RHOBTB1,HS3ST4,HS3ST2,DTNA,FARSB,ABCC5,GOLT1B,EDNRB,ANKRD46,MBNL2,KMT5B,GOLGA7,IRAK4,EMX2,EPHA5,EPS8,IGSF6,TMEM74,CDKL3,DNAJC27,F3,RPS6KC1,CACNG3,EFEMP1,FER,MED12L,CAMSAP1,POLK,WDR83,HVCN1,USP16,ATP2C1,FYB1,AHCYL1,ZMYND11,IP6K3,ERAP1,SIGLEC8,TUBGCP4,GGTA1P,GLRB,TNRC6A,MAP7D2,GPD2,LILRA1,GPR34,FAM222A,C1orf94,ZHX1,HNMT,SMAP1,MSL1,RBPJ,IL6ST,JAK1,OLFM3,KCNMA1,KCNN3,LIG4,SYTL4,NAT8L,MARK1,MEF2C,SRSF12,KITLG,COMMD5,MYO9A,NACA,NAP1L1,NELL1,NOVA1,NPTX2,NRCAM,NUMA1,TBC1D25,OLR1,GPR137C,PAK3,CNTN3,PCDH9,PRTG,CCSER2,PLP1,MTRF1L,PRIMPOL,LRP12,EXOSC10,PRRX1,ING3,SEPT4,POU3F2,TATDN3,PKIA,PKN2,RELN,MDGA2,TMEM260,STK32A,PTPRE,CEP97,ARID4A,KHDRBS2,RDX,RET,FIGN,RFX3,RGS12,RIC8B,RNH1,SETD5,GSTCD,TMEM206,RPE65,ATAT1,RTKN,AMER2,SCN2A,LRRTM4,LINC00461,TNFRSF19,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,SLC1A7,PPP4R3A,TET1,SMARCC2,RCOR3,RBM34,TRERF1,HECW1,PEG10,KIF1B,IQSEC2,CDK19,ZBTB43,RBM26,LMO3,ATP10B,POGZ,NXT2,RGL1,STXBP1,KLHL7,FGD4,DNAJC9,SYT1,DNMBP,CAMSAP2,UNC5D,ADGRL3,TBCEL,FBXW11,TCEA1,ZFP90,CUX2,TCF7L2,ZEB1,SZT2,PCDHB9,USP32P1,TEX15,ZFPM2,ITGB3BP,LEFTY2,AP4E1,GZF1,TMOD1,RGMB,PPIL6,TUBB1,UGT8,TOM1L2,VLDLR,PCDH20,ZIC3,ZNF711,LYPD6,CELF4,ZNF154,LAMP5,SYNC,PRDM2,PRTFDC1,RGMA,PRDM8,PRDM10,PCDH15,C12orf4,FAM13C,DOCK8,PAK5,ADAMTSL3,NLRP3,MSRB3,ZDHHC20,IFT88,SLC4A10" MicroRNA hsa-miR-369-3p:PITA hsa-miR-369-3p:PITA_TOP PITA 8.84E-92 4.96E-88 4.77E-91 4.39E-90 178 553 "RALGAPA1,ACLY,SLITRK1,USP31,PWWP2A,AP2A1,GPR158,PCDH19,ARHGAP20,FAM135A,LRCH2,LCORL,CACHD1,BCAS1,CASK,ARHGAP5,ZBTB10,EIF4G3,SYNJ1,ARHGEF7,NIPA1,CACNB2,CDH2,NOG,NUMBL,CFL2,CHN2,CNOT8,FAM19A5,DNAJB5,MAP4K4,NIPBL,BAG4,ZNF521,SLC35F1,PHACTR3,ZFYVE16,KCTD8,GIT2,DNAJC6,ZEB2,KLHL3,DMD,RCAN1,DYRK1A,HIPK3,SEMA3D,YAF2,MBNL2,TENM1,EML1,EPB41,SEZ6,ETV1,EYA1,ACSL4,MEX3B,FOXG1,PDLIM5,FYN,MEGF10,CHL1,GABRB3,GFRA2,SPIN1,GLRB,TNRC6A,GPM6A,STON1,RFFL,FAM19A2,PTPN5,ZBTB49,GUCY1A2,ADAMTS6,KLF12,BACH2,ELOVL5,C5orf24,NKD1,RBPJ,KCNJ3,KTN1,MAP2,MBNL1,CHIC1,LRP1B,MEIS1,MGAT3,AFF1,MYO5A,NEFM,NEUROD1,NF1,NPTX1,NRCAM,HCN1,OPA1,CNTN3,PDE4B,PDE4D,GPR85,CDK14,ANLN,PIK3R1,MINDY2,PPP2R2C,PRKAB2,CEP41,PKIA,SNRK,PTCH1,RAB5B,OXR1,ARID4A,KHDRBS2,ZFHX4,SPIN3,NCBP3,SATB1,FNIP1,ELMOD1,PPP1R9A,CPEB3,NTNG1,ST3GAL3,SLC1A2,WDR47,SLC6A1,SNAP25,MYO16,SOX1,SOX2,ZNF423,CDK19,RBM26,SRPK2,SSTR1,NKAIN2,GSE1,PRRC2C,ANKRD28,FBXW11,ATMIN,TCF4,ZEB1,TRIM2,RPGRIP1L,TCF12,PCDHGA11,DICER1,ZFPM2,SLC44A1,TJP1,TLL2,HEY2,RBFOX2,TRPS1,ZMYND8,TMEFF2,VSNL1,ZIC3,ZNF711,FMN2,ZBTB38,REEP1,ZFAND5,RNF103,NAV3,RGS7BP,GOPC,HNRNPA3,PHTF2,JMJD1C,PIANP,RNF146,ST8SIA2,SLC4A10" MicroRNA hsa-miR-2117:mirSVR_highEffct hsa-miR-2117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-92 5.10E-88 4.89E-91 4.51E-90 255 1142 "KLHL32,SLITRK1,PWWP2A,AP2A2,INTS2,HECW2,OSBPL1A,BCAR3,UNC79,PPFIA1,PKP4,PPFIA3,ATP2A2,ATP2B1,ATP2B3,TTLL9,MPDZ,SEC11C,BMPR1B,JAZF1,CA4,DDR1,RUNX1T1,USP6,MTMR7,P2RX6,SEPT7,CDC27,NOG,TAOK2,CPNE6,PLAA,PPT2,MAP4K4,NCOR1,GDA,SNCAIP,OSBPL3,SIPA1L1,PDE4DIP,PLXNA4,UBXN2A,CTNND1,EDRF1,GPRASP1,TOMM20,GIT2,DNAJC6,JAKMIP2,C8orf34,ZEB2,SPOCK3,AK5,SGSM2,RAB39B,DMD,USP3,CPEB2,DPH1,DSCAM,ECM2,E2F5,EBF1,SGK2,YAF2,FAM13A,PHF20L1,EGFR,KMT5B,ABI2,AASS,MRNIP,CALCRL,EN2,COQ7,SRRM1,MRPL37,NRN1,CLVS1,RPS6KC1,GORAB,SLC9B2,FGF13,SMC2,HVCN1,STAMBP,MSANTD4,AP4B1,SDCBP2,GABRB1,GAD2,IQGAP2,KIAA1841,TUBGCP4,TUBA8,PPARGC1A,NTNG2,GLS,MSL3,ZNF638,GPM6B,CCDC184,MCHR1,GRIA4,PLCD4,GRIK2,ATE1,CIT,LINC00839,FAM19A2,LINC01551,LINGO1,PSIP1,GABARAPL2,SMAP1,DOCK7,LRRCC1,USP54,SCIN,ITPKB,KCNMA1,KIF5C,LAMP2,STMN1,PAXBP1,NCOA7,MAP6,MAT2A,MDM4,MEF2C,MEIS1,MEIS2,MITF,MRPL42,MTTP,NDUFA5,NF1,SLCO1C1,DNHD1,NPTX1,SLC11A2,NRCAM,GPR88,TREM2,SNTG1,PDE4B,PDE4D,PDE1B,PDGFRA,PDPK1,CYTL1,HERC2P3,ZNF655,PLCL1,JAKMIP1,PDZRN4,SCHIP1,SPATA6,POU3F2,PPP1R1A,PRKACB,RAB39A,HYDIN,MASP1,CNTLN,TMEM260,PTPRB,PTPRN,PPP2R3C,RAB5B,PBRM1,RNASEL,CARF,RORB,RPL15,ATP8B4,ACER3,LGR4,ABCA11P,NCBP3,ZNF331,FAM192A,SEMA6D,SH3BGR,ITSN1,SH3GL2,SH3GL3,CPEB3,MYO18A,DOCK10,HKDC1,NLGN1,PPP4R3A,FAM214B,SLC8A1,SLC12A2,SLCO1A2,SORCS3,ANKRD36,KIF13A,SOX2,TNIK,SOX5,GLT8D1,SPP1,ZC3H13,NFASC,TAB2,TROVE2,LARP4,RGL1,VPS13A,KAZN,DDHD2,MLST8,TMEM136,KLHL4,TBX15,SATB2,TCF12,WDR7,TEK,FAM200B,LEFTY2,FBXL16,ERCC6L2,C5orf64,CA14,ANKRD20A2,TTPA,ZNF610,PLEKHH2,BCL2L13,MTCH1,MEAF6,VLDLR,ZIC3,ZNF711,MKRN3,ZNF138,LINC02210,PRDM10,HPS4,FIP1L1,SLC17A6,PDSS2,RGS7BP,GOPC,FZD3,ST7,PAK5,PHTF2,MSRB3,IFT88,JPH3" MicroRNA hsa-miR-520a-3p:mirSVR_highEffct hsa-miR-520a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.76E-91 9.90E-88 9.50E-91 8.75E-90 266 1241 "KIAA1211,PTCHD1,MTUS1,GPR158,KLHL13,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,RGS20,STK33,STX16,DPY19L3,BACH1,DCAF5,BID,CFLAR,DST,ST3GAL5,MTMR3,JAZF1,CA12,CALB2,SYT6,AIFM1,ZBED1,MAGI1,CLGN,CFL2,CHN2,TAOK2,ABCG2,C4orf33,HECTD1,AKAP5,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,TOX,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,HS3ST4,HS3ST2,DMTF1,DRD1,DNAJB6,DNM1L,GOLT1B,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,TENM1,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,TACC2,USP16,MSANTD4,FYB1,MEGF11,ZMYND11,ARPP21,IGSF5,GGTA1P,COPS8,TNRC6A,GLUL,ZNF638,MAP7D2,GPM6A,GPR34,PCLO,GRIA1,GRM5,TMEM25,HPS5,C1orf94,ARHGAP36,HSP90AA1,SMAP1,MSL1,IDH3B,IGSF1,JAK1,OLFM3,KCNMA1,KCNN2,LAMP2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,MDM4,SRSF12,KITLG,PPM1L,POC1B,ADAM22,MYCN,LAYN,MYO9A,NACA,NELL2,NEUROD1,NF1,NRCAM,NUMA1,OCRL,OGG1,OPHN1,PCDH9,PDCD2,PFKP,ZDHHC8,ZNF655,PLCL1,JAKMIP1,PRIMPOL,TRHDE,PRRX1,SPATA6,DRAM2,MED1,PPP3CB,PRKACB,PKN2,MAPK9,GRAMD1C,MASP1,SNRK,PTHLH,TMEM260,TTC13,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,SLC1A6,YPEL4,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ZC3H13,IQSEC2,ZBTB43,LMO3,ATP10B,POGZ,RGL1,STXBP1,FGD4,SYNE2,DNAJC9,CAMTA1,CAMSAP2,UNC5D,ADGRL3,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,HHIP,AKTIP,TIAM1,NR2E1,TNS1,TPD52L2,RGMB,PPIL6,PITPNB,ZNF709,VLDLR,VSNL1,LYPD6,LAMP5,SYNC,CADM2,RGMA,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,PAK5,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-203a-3p.2:TargetScan hsa-miR-203a-3p.2 TargetScan 1.88E-91 1.05E-87 1.01E-90 9.30E-90 210 782 "NDRG3,ADARB2,BRAP,KIAA1211,PCDH19,KCTD16,OSBPL1A,OSBPL8,PCDH10,AMPD3,PHF12,APBB2,APC,DGKZ,CASK,ARNTL,CDK13,PDE8B,MARCH3,DDX3Y,INSYN2B,ATM,ADAM23,MPDZ,BCL2L2,BCL7A,DST,BSN,LDLRAD4,FOXK1,CA12,CACNA1E,CABP7,RUNX1T1,KRIT1,INA,CDH2,CDH10,NUMBL,NRXN3,PLAA,COG1,CLTC,C4orf33,HECTD1,CNTFR,NRG2,CLOCK,RBM39,ANKRD44,NCOR1,MICAL2,PLXNA4,APPL1,PNPLA8,PUM1,PHF19,MATR3,DGKB,DNAL1,DCC,NR1D2,GNE,DYRK1A,DNM1L,EBF1,FAM135B,EDNRA,HEYL,FSD1L,CACNG7,FAM13A,MBNL2,EGR3,RGS17,EN2,GPHN,ANKRD13B,NCALD,ETV1,MRVI1,ANKFY1,AFF2,NBEA,ATP2C1,NSG1,MSANTD4,FYN,MEGF11,GABRA1,GABRA5,GALNT15,GABRB3,CAB39,GAD2,NKX6-2,MYOZ2,GATM,GBX2,PCDH17,GPR75,GLS,GNG4,NUDT21,RAPGEF4,RAPGEF1,RFFL,ADAMTS8,PTPRT,GUCY1A2,PADI2,NXPH3,NCKAP1L,NEGR1,HTR2A,MSL1,NKD1,KCNB1,KCNC1,CLVS2,KCNN3,KCNQ3,KIF2A,CYP27C1,LAMP2,LIFR,C2orf80,GPR155,MBNL1,MEF2C,MGAT3,PPM1L,MMP16,SAMD5,JAKMIP3,NRBP2,HS6ST3,MXI1,MYO5A,NFYA,NOVA1,KCNK10,PCDH8,PCDH9,PCSK2,PDE3B,PDE4D,PDGFRA,GPR85,GNG2,PIK3C2A,EPB41L4B,FAT3,PKIA,PRKCB,MAPK8,MAPK9,MAPK10,PROX1,PTCH1,EML5,PTPRG,RASGRF1,ERI2,GTDC1,RGS7,PBRM1,RAVER2,ROBO1,ROBO2,RIMKLA,CCDC112,AP1AR,AMER2,ELMOD1,DOCK10,CHD9,FBXO11,ABLIM3,DHX30,CCDC88A,BTBD7,CPEB4,MBD5,FAM126B,NMNAT2,CLSTN2,AJAP1,FAM168A,FGD4,ADAMTS17,ATP11A,KAZN,CAMTA1,FAM208A,KIAA0930,RPGRIP1L,PSD3,DICER1,CBX5,DDHD1,KAT6B,FAM155A,AMOT,FLRT2,MICU3,C12orf4,KAT6A,JMJD1C,GAN" MicroRNA hsa-miR-1323:PITA hsa-miR-1323:PITA_TOP PITA 1.90E-91 1.07E-87 1.02E-90 9.39E-90 194 665 "ASIC2,ADCY2,NLGN4X,AP2A1,INTS2,GPR158,OSBPL1A,OSBPL8,LRRC7,SEMA6A,ALCAM,AMPH,CDC42BPA,DPP10,ANK1,ANK3,MAP4K3,GPAM,SHTN1,TMEFF1,ASCL1,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B1,NRP2,CDK5R1,SYNJ1,FOXK1,RUNX1T1,C1orf52,FOXN3,B4GALT6,LHX2,KMT2C,NRXN3,CLCN4,CLTC,TMEM184B,MAGED1,CLOCK,CRMP1,GDA,CSNK1G3,SLITRK5,ERC2,RIMS2,KIAA0408,DOCK4,TOMM20,HP1BP3,ZC3H11A,FAM107B,DLG2,USP3,CPEB2,CASP8AP2,DNAJB6,DYRK1A,HIPK3,SEMA3D,KMT5B,ABI2,GOLGA7,EIF4G2,PLEKHA1,ELAVL3,PAN3,ETV1,ATP8A1,FGFR3,CAMSAP1,CAP2,DACH2,STAG2,GABRB3,BRPF3,NCKAP1,PCDH17,PPARGC1A,GPM6A,NUDT21,GRB10,CIT,SOX21,ZHX1,BACH2,MIER3,HLF,HMGCR,C5orf24,BRINP3,LRRTM3,OLFM3,KCNC2,KIT,KTN1,NAT8L,MBNL1,LRP1B,MEF2C,SESN3,MYCN,MYO6,NEXMIF,MYT1,NFIA,NOVA1,OLR1,PCSK1,PCSK2,GPR85,GNG2,CDK14,RETREG1,NLE1,STRN3,PPARA,MED1,PPP2R5E,VSTM2L,PTPRD,PTPRG,USP47,OXR1,ARID4A,FIGN,RFX2,RIT2,SLC25A36,ZFHX4,PCMTD2,RPE,RIMKLA,CLIP1,RTN1,SCN4B,FAM19A1,FNIP1,TNFRSF19,HSPA4L,KIF21A,FBXO11,PPP4R3A,EPN2,NAPB,ATF7IP,FAIM2,PDZD2,MYT1L,SOX5,SOX15,SP4,LHFPL4,KDM4C,SRPK2,CLASP2,SS18,ST5,GSE1,KLHL7,FGD4,PLCB1,CAMTA1,TBL1X,TCEA1,RPGRIP1L,SYNE1,TEK,TMEM121,HHIP,TIAM1,TLL2,ERCC6L2,PRMT8,TUBB2A,SGK3,RPRM,UBTF,UGT8,FLRT2,VGF,WIPF1,NSD2,ZFAND5,WNK1,PMEPA1,EMSY,MFF,PRDM8,NAV3,PAK5,SOCS4" MicroRNA hsa-miR-548o:PITA hsa-miR-548o:PITA_TOP PITA 1.90E-91 1.07E-87 1.02E-90 9.39E-90 194 665 "ASIC2,ADCY2,NLGN4X,AP2A1,INTS2,GPR158,OSBPL1A,OSBPL8,LRRC7,SEMA6A,ALCAM,AMPH,CDC42BPA,DPP10,ANK1,ANK3,MAP4K3,GPAM,SHTN1,TMEFF1,ASCL1,ZBTB10,CHRD,DDX3Y,SLC4A4,ATP2B1,NRP2,CDK5R1,SYNJ1,FOXK1,RUNX1T1,C1orf52,FOXN3,B4GALT6,LHX2,KMT2C,NRXN3,CLCN4,CLTC,TMEM184B,MAGED1,CLOCK,CRMP1,GDA,CSNK1G3,SLITRK5,ERC2,RIMS2,KIAA0408,DOCK4,TOMM20,HP1BP3,ZC3H11A,FAM107B,DLG2,USP3,CPEB2,CASP8AP2,DNAJB6,DYRK1A,HIPK3,SEMA3D,KMT5B,ABI2,GOLGA7,EIF4G2,PLEKHA1,ELAVL3,PAN3,ETV1,ATP8A1,FGFR3,CAMSAP1,CAP2,DACH2,STAG2,GABRB3,BRPF3,NCKAP1,PCDH17,PPARGC1A,GPM6A,NUDT21,GRB10,CIT,SOX21,ZHX1,BACH2,MIER3,HLF,HMGCR,C5orf24,BRINP3,LRRTM3,OLFM3,KCNC2,KIT,KTN1,NAT8L,MBNL1,LRP1B,MEF2C,SESN3,MYCN,MYO6,NEXMIF,MYT1,NFIA,NOVA1,OLR1,PCSK1,PCSK2,GPR85,GNG2,CDK14,RETREG1,NLE1,STRN3,PPARA,MED1,PPP2R5E,VSTM2L,PTPRD,PTPRG,USP47,OXR1,ARID4A,FIGN,RFX2,RIT2,SLC25A36,ZFHX4,PCMTD2,RPE,RIMKLA,CLIP1,RTN1,SCN4B,FAM19A1,FNIP1,TNFRSF19,HSPA4L,KIF21A,FBXO11,PPP4R3A,EPN2,NAPB,ATF7IP,FAIM2,PDZD2,MYT1L,SOX5,SOX15,SP4,LHFPL4,KDM4C,SRPK2,CLASP2,SS18,ST5,GSE1,KLHL7,FGD4,PLCB1,CAMTA1,TBL1X,TCEA1,RPGRIP1L,SYNE1,TEK,TMEM121,HHIP,TIAM1,TLL2,ERCC6L2,PRMT8,TUBB2A,SGK3,RPRM,UBTF,UGT8,FLRT2,VGF,WIPF1,NSD2,ZFAND5,WNK1,PMEPA1,EMSY,MFF,PRDM8,NAV3,PAK5,SOCS4" MicroRNA hsa-miR-613:mirSVR_highEffct hsa-miR-613:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.46E-91 1.38E-87 1.32E-90 1.21E-89 245 1062 "RALGAPA1,ABHD6,KDM5D,NDRG3,ADAR,CCDC85A,ERMN,HACE1,ALCAM,ARHGAP20,OGT,CCDC146,MAP4K3,SUGT1P4-STRA6LP-CCDC180,UPRT,ALS2,API5,MIER1,ASPH,ZNF582,FGF17,BMPR1B,SYNJ1,FUBP1,CA8,KALRN,CAST,MTMR7,CDC42,LGI1,L3MBTL4,MAGI1,UBE2L6,SOCS6,CLCN3,CLTC,C4orf33,TMEM155,CNN3,COL9A1,SLC4A8,BAG4,SLC35F1,CREM,CREB5,RNF14,CRYM,PDE4DIP,KIAA0513,MATR3,KCTD8,DGKB,DAPK1,GIT2,YTHDC1,ELMO1,TIAM2,SMG7,PLPPR4,DRD1,DTNB,ECM2,ABCC5,E2F5,AASDH,EDN1,SYT15,FAM13A,MRO,KMT5B,BSCL2,EMX2,EPHB1,KCNMB2,RABEPK,MRPL37,CDKL3,ADGRV1,DLC1,CEP78,FER,FGFR1,SEC23B,IP6K2,NELFCD,NBEA,SPECC1,UFM1,DACH2,ST6GALNAC3,FYB1,GABRA3,ILDR2,DENND2A,GAD2,HIGD1B,LRRC37A6P,KIAA1841,TUBGCP4,ARFIP1,PCDH17,PPARGC1A,GLS,FERMT2,WDFY3-AS2,ADGRA3,GPD2,MCHR1,RNF165,LINC01551,PSIP1,HLF,HMGCR,HNRNPK,ZDHHC15,EID2B,IGF1,RBPJ,LIX1,INSM1,SLC35G1,METTL21A,KCNK2,KIF2A,KTN1,LAMP2,MAP2,MEIS1,MRPL42,MYO9A,PABPC1L2A,NEUROD1,HCN1,IGSF11,OLR1,ZNF713,GPR137C,SNTG1,PDCD2,PIRT,PDGFRA,ENPP2,CDK14,GDAP1L1,NALCN,PURG,TRHDE,SCHIP1,MED1,MINDY2,PRKACB,MAPK3,GRAMD1C,TMEM260,ZIK1,OCIAD1,PTPRG,FAM66C,MSANTD2,SLC6A15,CRTAC1,ZMAT4,UBR7,RGS7,RIT2,SLC25A36,NUDT11,C12orf49,CARF,FBXW7,ACER3,KCNIP3,RYR3,SEMA6D,SCP2,ASRGL1,MRAS,TRA2B,ITSN1,SH3GL3,FNDC3A,ANKRD6,ZNF365,PEX26,SLC6A11,SLC8A1,RAB3GAP1,SLC15A2,ELMO2,TET1,SORCS3,ANKRD36,SNAP25,SNRPN,UNC80,USP33,SOX5,SP2,NPAS3,SAMSN1,LARP4,SS18,NXT2,SYN2,TACR1,ALG1,WWC1,KLHL4,ANO4,EHBP1,SATB2,TCF7L2,TRIM2,CLASP1,OBSL1,DICER1,DICER1-AS1,ZMAT3,SLC44A1,ARL10,TIMP4,LRRC8A,NPL,TPM3,TPM4,TRIO,AMACR,TTC3,RPL7L1,FAM155A,UBE2H,AMOT,UGT8,BEST1,TBC1D15,WNK1,TMEM178A,HPS4,WNK3,PARP11,ADAMTSL3,TIGD6,MSRB3,NETO2,SLC4A10" MicroRNA hsa-miR-129-3p:mirSVR_lowEffct hsa-miR-129-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.56E-91 1.44E-87 1.37E-90 1.26E-89 247 1079 "SDE2,ADCY2,ADD2,PWWP2A,ESYT2,ZNF578,ADGRF5,C1QTNF3,SYT13,ANK3,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,APAF1,SHTN1,AQP4,PDXK,CDK13,MARK4,NCOA1,RASL11B,NOL4,TTLL9,BCL2L2,CFLAR,KSR1,SCAPER,MYRF,LDLRAD4,CACNB2,KALRN,SHISA7,CLDN10,CCKBR,LARGE1,RCBTB2,SRSF11,CHN2,RAB28,PLAA,DNAJB5,MAP4K4,NIPBL,ARHGEF6,AKAP6,AKAP5,RCHY1,FAM171B,SH2B1,AKAP12,SEC24C,FEZ1,OSBPL3,ERC2,CFAP61,CTNND2,DCAF4,RUBCN,HDAC9,RIMS3,SPOCK2,IP6K1,AIF1L,ARMCX4,ZEB2,MYEF2,TIAM2,RUSC2,ALKBH8,DLG2,DNM1,HS3ST2,GNE,ECM2,ABCC9,PHC2,TMTC1,FRY,SIDT2,GPR61,EBI3,VPS13B,EPHA5,MRPL37,TOMM40L,GORAB,OLFM1,FGF13,SUCO,MEX3B,PCYOX1,C2orf88,TPK1,ARFGAP2,CAMKK2,ATP2C1,ERGIC3,CELF1,MSANTD4,TVP23A,GABRG1,AHCYL1,BRPF3,B4GALNT1,NEK6,ATP8A2,LRRC37A6P,KDM2B,GPD1,GPM6B,GRIA4,CACFD1,GRIN2C,NR3C1,CLASRP,RNF165,TMEM179,TOX2,HMGB1,HMGCL,SHISA6,MSL1,TJAP1,IL12A,ITPKA,GPR62,STXBP5,CYP27C1,TTYH2,SYTL4,MAP4,SYT9,AFF1,XRRA1,ADAM22,MSR1,MTR,ZNF862,SFR1,NEK1,NOS1,CNOT4,NTRK2,NUMA1,TBC1D25,PDCD2,PRTG,PDE3B,NALCN,SEMA5B,PLXNB1,EXOSC10,POLG,MED1,PPP2R5E,RASGEF1B,PRKCB,MAPK3,PSD,QRICH1,ELOVL2,PTPRG,PTPRO,PEX5,RAP1GDS1,BSDC1,TRIM68,GTDC1,RFX4,UBR7,RLBP1,ZNF532,GSTCD,ROBO1,SNX22,ATAT1,ZNF568,STX1B,FAM192A,SEC14L1,KIF21A,FBXO11,R3HDM2,CNKSR2,PAAF1,ZNF365,EPN2,SLC6A8,SLC14A1,BTBD7,SPHKAP,SLN,CXXC4,SNRPN,SCN3B,WDTC1,SOX2,SOX5,SOX10,NMNAT2,STAU1,CEP68,PHLDB1,SEPT3,NSFL1C,ACSBG1,VAMP1,VPS13A,TMEM150C,SYT1,COBL,KLHL4,TCF7L2,CLASP1,SYNE1,USP32P1,CYB561A3,LEFTY2,AP4E1,TGFBR3,MTMR14,TMPO,RGMB,ELP5,NEIL2,AMACR,FNDC5,CADM1,UBE3A,RICTOR,SF1,SLC26A10,ZBTB38,AMZ1,MEIS3,DNALI1,STOX2,HPS4,GAL3ST3,NAV3,C12orf4,HNRNPA3,FBXO36,CAMK1G,NUP214,VANGL2" MicroRNA hsa-miR-1263:mirSVR_lowEffct hsa-miR-1263:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.13E-91 2.88E-87 2.75E-90 2.53E-89 226 910 "ACADM,CSMD2,GALNT16,ADCY6,SLC12A5,ERMN,PWWP2A,BEND6,TAOK1,USP35,ARHGAP20,ALK,LRCH2,UPRT,TNRC6C,TMEFF1,ARHGAP5,RIPK1,DOCK11,ADAM23,BCL7A,BID,CACNA1B,CACNB4,HIP1R,CD38,ARHGEF2,CDH2,LGI1,NUMBL,COPB2,ADGRG1,SRSF11,ASIC3,RAB3C,CHRNB2,ARHGAP22,CLCN3,MYL6B,COL9A1,ZNF521,CS,SEC24C,SUSD5,FAM169A,KIAA0040,PLCXD3,DCAF4,ARHGAP24,TOX,TOMM20,YTHDC1,ZEB2,KIAA0319,MAGI2,PLPPR4,SGSM2,DNM1,HS3ST2,DOCK2,ACOT8,ABI1,DYRK1A,E2F6,EDNRA,RASGRP1,YAF2,SUGP2,MBNL2,EML1,EPHA5,GPHN,CDKL3,CORO2B,DLC1,RACK1,CEP78,SEC24B,FGF12,CAP2,ATP13A4,NOP56,NELFCD,EFCAB2,FAM49B,CELF1,ADGRA1,MEGF10,GAD1,ARPP21,IP6K3,ACSS1,ALDH1L1,ARFIP1,NR3C1,GRM7,ZNF496,BTN2A1,MFSD2A,LINC01551,GUCY1A2,RASSF8,RBPJ,DOCK7,LIX1,IL6ST,IL12A,SLC35G1,KCNA1,KCNJ10,KCNK2,KCNN1,STXBP5,INSYN2,HECTD2,KCTD6,MID1,COL28A1,NAP1L1,NAP1L3,NEFM,ALDH1L2,NFYA,NTRK2,PCDH9,PCSK5,ENPP2,PDPK1,GPR85,ZNF655,FAM216A,ANKRD16,STRN3,RETREG2,EPB41L4B,SH3KBP1,FSD1,PPP2R2C,PPP2R5C,PRKACB,PRKCB,MAPK10,PRPH,WBP1L,PTHLH,PTN,PTPRG,PTPRN,PTPRO,FAM184A,NWD1,RAP1GDS1,ENOX1,MSANTD2,RFX3,RFX4,ZFHX4,CARF,PNMA8A,ROBO2,NEK11,EPHA10,GLDN,HUNK,RTN1,HOGA1,SCN2A,LRRTM4,FAM19A1,SCN8A,HES6,SLC30A10,PEAR1,SFPQ,SUPT20H,CTXN2,NUBPL,PPP4R3A,EPN2,RUFY2,KANSL3,SLC20A2,ANKRD36,SNRPN,SON,KIF21B,BDP1,TROVE2,NEK4,PRRC2C,SYP,FBXW11,VWA3A,EHBP1,ACSL6,TPCN2,TRIM2,RPGRIP1L,NAT16,DOCK9,USP32P1,SIK3,DICER1,ZFPM2,ZMAT3,TLL2,TLR4,C5orf64,LRTM2,SLC35A4,SLAIN1,LAT2,PCDH20,ZNF708,TRIM9,FTSJ1,EMSY,LRP8,STOX2,ADAMTS9,PCDH15,GAL3ST3,MPPE1,SLC17A6,FAM219B,JMJD1C" MicroRNA hsa-miR-2116:mirSVR_highEffct hsa-miR-2116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.93E-91 3.90E-87 3.71E-90 3.42E-89 258 1178 "CLK4,ARID1A,GALNT13,ADD3,ERMN,GRAMD1B,PTCHD1,OLMALINC,HECW2,AGT,SORCS2,OSBPL8,ADGRF5,C1QTNF3,ALCAM,UNC79,ZFAT,OGT,MAP4K3,PPFIA1,ANXA7,PDE8B,ASPH,ZBTB10,NCOA1,EIF4G3,ATP2B1,B3GALT2,DPY19L3,BACH1,ARHGEF7,FUBP1,SCAPER,CA8,THSD7A,KALRN,CAMK2D,RUNX1T1,ZNF501,TMEM257,SOCS6,CHM,CASC2,COG1,HECTD1,IQCK,SLC25A27,ABI3BP,ACBD5,MYRIP,CHD1L,NECTIN3,CPS1,PREPL,RBM39,AKAP12,HAPLN1,GDA,FEZ2,OSBPL3,GPRASP1,GAPVD1,RIPOR2,HDAC4,TOX,LONRF1,MATR3,DNAL1,JAKMIP2,C8orf34,ZEB2,SPOCK3,USP3,DNM2,DPYSL2,PDCD6IP,GOLT1B,EDNRA,SGK2,TMTC1,FRY,OPTN,RBM12,PHF20L1,KMT5B,PLEKHA1,MRNIP,PAN3,DCTN4,ZNF549,EXTL2,CLVS1,CACNG2,TAOK3,CEP78,KIAA1109,FGF14,POLK,IP6K2,NELFCD,C2orf88,EFCAB2,PDLIM5,USP21,DACH2,AP4B1,FYB1,ZMAT1,GABRA1,CAB39,GAD2,IP6K3,ZNF559,DNER,MYOZ2,GCNT2,PCDH17,GHR,NTNG2,COPS8,TOX3,ZNF782,GPD2,STON1,ATP2B1-AS1,GRIA2,KIF3A,TMEM25,ATG4C,RASSF8,PADI2,HMGB1,IL12A,NME9,KCNA4,KIFC3,IPO5,NCOA7,MARK1,MBNL1,TM6SF1,MEF2C,MEST,MITF,AFDN,NCAM2,NF1,NFE2L2,DNHD1,NPTX2,CLEC9A,SLC11A2,HCN1,OLR1,TREM2,GLIPR1L2,PAK3,PCSK5,PFKFB2,FAM98B,CDK14,PIK3C2A,A2ML1,FAM216A,PCDH18,MTRF1L,TRHDE,SLC36A4,MED1,MINDY2,RAB39A,GRAMD1C,SAMD9,ANKHD1,ELOVL2,PTPRG,PTPRO,C1orf109,ZSCAN2,PPP2R3C,MARCH1,USP47,ARID4A,ZMAT4,TRIM68,FIGN,RPRD1A,ROBO1,RPE,ATP8B4,LRRK2,CNTNAP3,CLIP1,SCN2B,IL17RB,ZFP30,KIF16B,SHC4,SEC31A,WDR37,ABLIM3,FAM214B,ZNF430,CCDC88A,SLC12A2,MTERF2,BTBD7,SMARCE1,SNCA,SNRPN,PALLD,UNC80,MYT1L,TNIK,EMC1,KDM4C,IDI2-AS1,TAB2,PBLD,SSTR1,NECAB1,SYNE2,ARHGEF9,VPS13A,C12orf76,SEMA4A,CAMSAP2,ADGRL3,SATB2,ZEB1,TRIM2,CLASP1,PCDHB6,GPRIN3,LEFTY2,TMOD1,C9orf85,SMUG1,TRIO,TTC3,SGK3,UGT8,PITPNB,CCDC136,XPO1,ZNF708,FMN2,MKRN3,CELF4,SMARCAD1,ZNF225,PCDH15,SLC17A6,DOCK8,PHTF2,FBXO36,RNF170,MSRB3" MicroRNA "TTTGCAC,MIR-19A:MSigDB" "TTTGCAC,MIR-19A:MSigDB" MSigDB 1.16E-90 6.51E-87 6.18E-90 5.70E-89 166 483 "ABR,ACTN1,SLC24A4,HECW2,PCDH10,PITPNM2,OGT,LRCH2,ANXA7,SHTN1,MIER1,ARHGAP5,CDK13,ZBTB10,DDX3Y,ATP2B2,NRP2,ST3GAL5,NIPA1,BSN,CALM1,CAST,PRC1,USP6,SEPT7,EVI5L,ZFYVE9,PLAA,CLTC,QKI,CNTFR,ARMC8,BTF3L4,ACBD5,SLC35F1,CLOCK,GDA,CS,LRIG1,SOCS5,PPP6R2,SNPH,HDAC4,LONRF1,DBN1,SPATA2,CEP170,MAGI2,SV2A,SRGAP3,G3BP2,WDR20,ARRDC4,ST8SIA3,MBNL2,PLXNC1,EMX2,ERBB4,NCALD,ETV1,F3,ACSL4,PTK2B,DLC1,TESK2,MED12L,OLFM1,CAMSAP1,FOXF2,FLNC,NBEA,ATP2C1,CAB39,ZMYND11,ARFIP1,TNRC6A,CBX1,RAPGEF4,GRM7,KIF3A,RNF165,SOX21,HLF,ELOVL5,IGF1,KCNA4,KIT,ARHGAP12,MBNL1,AFF1,MYCN,NEUROD1,CNOT4,OCRL,PFKFB3,CCSER2,TNPO2,POU3F2,PPARA,PPP2R5E,PSD,WBP1L,PTPRG,RAB5B,ATG16L1,RBBP8,RFX4,ROBO2,PRR5L,RIMKLA,RTN1,RXRA,ATXN1,SOX6,SGK1,ITSN1,FNDC3A,SYBU,EPN2,WDR47,SLC6A8,CCDC88A,SHANK2,NAPB,BTBD7,CPEB4,USP33,SOX5,CDK19,SPART,SMOC1,RGL1,SYT11,PRRC2C,C3orf70,PLCB1,ARC,SYT1,ATP11A,ANKRD12,CAMTA1,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZFP91,CSMD1,WBP2,TRPS1,TSC1,USP32P2,SPHK2,DPYSL5,SPIRE1,PMEPA1,MAP3K12,NAV3,SNX27,PHTF2,CBLN2" MicroRNA "TTTGCAC,MIR-19B:MSigDB" "TTTGCAC,MIR-19B:MSigDB" MSigDB 1.16E-90 6.51E-87 6.18E-90 5.70E-89 166 483 "ABR,ACTN1,SLC24A4,HECW2,PCDH10,PITPNM2,OGT,LRCH2,ANXA7,SHTN1,MIER1,ARHGAP5,CDK13,ZBTB10,DDX3Y,ATP2B2,NRP2,ST3GAL5,NIPA1,BSN,CALM1,CAST,PRC1,USP6,SEPT7,EVI5L,ZFYVE9,PLAA,CLTC,QKI,CNTFR,ARMC8,BTF3L4,ACBD5,SLC35F1,CLOCK,GDA,CS,LRIG1,SOCS5,PPP6R2,SNPH,HDAC4,LONRF1,DBN1,SPATA2,CEP170,MAGI2,SV2A,SRGAP3,G3BP2,WDR20,ARRDC4,ST8SIA3,MBNL2,PLXNC1,EMX2,ERBB4,NCALD,ETV1,F3,ACSL4,PTK2B,DLC1,TESK2,MED12L,OLFM1,CAMSAP1,FOXF2,FLNC,NBEA,ATP2C1,CAB39,ZMYND11,ARFIP1,TNRC6A,CBX1,RAPGEF4,GRM7,KIF3A,RNF165,SOX21,HLF,ELOVL5,IGF1,KCNA4,KIT,ARHGAP12,MBNL1,AFF1,MYCN,NEUROD1,CNOT4,OCRL,PFKFB3,CCSER2,TNPO2,POU3F2,PPARA,PPP2R5E,PSD,WBP1L,PTPRG,RAB5B,ATG16L1,RBBP8,RFX4,ROBO2,PRR5L,RIMKLA,RTN1,RXRA,ATXN1,SOX6,SGK1,ITSN1,FNDC3A,SYBU,EPN2,WDR47,SLC6A8,CCDC88A,SHANK2,NAPB,BTBD7,CPEB4,USP33,SOX5,CDK19,SPART,SMOC1,RGL1,SYT11,PRRC2C,C3orf70,PLCB1,ARC,SYT1,ATP11A,ANKRD12,CAMTA1,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,ZFPM2,ZFP91,CSMD1,WBP2,TRPS1,TSC1,USP32P2,SPHK2,DPYSL5,SPIRE1,PMEPA1,MAP3K12,NAV3,SNX27,PHTF2,CBLN2" MicroRNA hsa-miR-525-5p:mirSVR_highEffct hsa-miR-525-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.64E-90 9.18E-87 8.72E-90 8.03E-89 236 996 "ASIC2,XKR4,BRAP,FZD9,CC2D2A,NT5C3B,PPP4R4,RGS20,CDK13,CAPRIN2,ASPH,NUMB,RASL11B,SLC4A4,N4BP2L1,ADGRB3,KSR1,MMD2,KALRN,CBFA2T2,SEPT7,CFL2,CHN2,JAM2,IGFBP7-AS1,CLTB,QKI,SULT4A1,COL9A1,BTF3L4,ABI3BP,SMARCAL1,CHD1L,FAM171B,ANKRD44,CSNK1G3,ATRNL1,PLXNA4,ERC2,ARHGEF4,NRSN1,DOCK4,RIPOR2,DCAF8,TOX,DAPK1,SIRPA,ARMCX4,KIAA0753,GSDME,DDX46,SNAP91,SPOCK3,TMCC2,DPP6,DRP2,ECM2,ABCC5,ABCC9,SNX29,RASGRP1,EGFR,KMT5B,ELN,TUBD1,EPB41L1,EPB41L2,TLR7,TUBB4A,ST3GAL6,CEP78,FCGR3A,FER,PCYOX1,ATP6V1H,ZNF605,CELF1,SARAF,AP4B1,ZNF512,GABRA1,ILDR2,GALC,IQGAP2,INPP5K,TUBGCP4,SESN1,GFRA2,HEPN1,PCDH11X,INSM2,GPM6B,GRIA2,GRIA4,PLCD4,COQ10A,IRAK3,VSIG4,HMGCL,AGBL5,OPALIN,SHISA6,IDH3B,IGF1,USP54,ITPKB,KCNB1,KCNJ3,KCNK2,CREG2,KIF2A,IPO5,PAXBP1,SMAD1,MEIS1,MEIS2,MID1,POC1B,MN1,MOBP,MOG,MTTP,RSPO2,NDP,NODAL,NOVA1,NUCB2,ODF2,OLR1,PBX1,PDE3B,PFKFB2,HERC2P3,RETREG1,XRN1,GPSM2,PLP1,HMGCLL1,ZNF426,MAPKAP1,TNPO2,NXPH1,PPP2R5E,RANBP3L,RAB39A,SLC26A11,GRAMD1C,DIRAS2,MDGA2,PSMD13,ANKHD1,MTMR10,PTK2,TMEM260,PTPRB,EML5,RALGDS,SUSD4,ENOX1,ZYG11B,PRRT2,FIGN,UBR7,RGS4,RIC8B,TMLHE,ARMC5,CARF,NEK11,ACER3,RTN1,SEMA6D,ATXN2,ATXN7,FAM19A1,SOX6,ASRGL1,SGK1,SH3GL3,FBXO11,PAAF1,PPP4R3A,SLC22A4,ANKRD36,DOP1A,SON,KDM3A,UHRF1BP1L,KDM4C,KIF1B,RBM26,EPB41L3,NKAIN2,MAPK8IP3,ZSCAN29,CEP68,ACSBG1,PRRC2C,SYNE2,VPS13A,FAM208A,FBXW11,KLHL4,ATMIN,EHBP1,SATB2,RPGRIP1L,WASHC4,SYNE1,NAT16,PUM2,CRB1,AP4E1,TMPO,ZNF384,ZNF346,TRO,SLAIN1,CCDC14,XPO1,ZNF24,ZNF32,FMN2,TCEAL7,CADM2,SCG2,VPS35L,PCDH15,PPP1R3F,TMEM163,PLSCR4,PDSS2,UBE3B,PAK5,NHSL1,ZDHHC20" MicroRNA hsa-miR-148b*:mirSVR_highEffct hsa-miR-148b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.13E-90 1.20E-86 1.14E-89 1.05E-88 254 1149 "ASIC2,C3orf14,FMNL2,TMCC3,HECW2,KIAA1324,OSBPL8,CC2D2A,PCDH10,CNIH2,APC,USP37,MIER1,MARCH3,ATP2A2,RNF182,DPY19L3,TTLL9,CFLAR,DST,JAZF1,PTBP2,SLC25A14,CAST,RUNX1T1,AP4M1,SYNPR,B4GALT6,SLIT2,KMT2C,DLGAP3,SUMF2,RCHY1,CLIP3,SNCAIP,CSF2RA,MICAL2,PUM1,ZSCAN23,CX3CR1,EARS2,FBXL5,GSDME,DDX46,SMG7,SACS,RABGAP1L,DLX1,USP3,NR1D2,CPEB2,DOCK2,DPYSL2,ABI1,PDCD6IP,FAM135B,EDNRB,SYT15,FRY,FAM13A,LPAR6,COPS4,PLEKHA1,EPHB1,GPHN,ERCC2,EYA1,WAC,FCGR1B,FCGR3A,SEC24B,FGF12,FGF13,FGFR1,FHL1,POLK,VTI1B,ATP13A4,SORBS1,SMC2,APOPT1,UFM1,KHDRBS3,AP4B1,STAG2,GABRA2,GABRG2,ZMYND11,DISC1,DNER,IGSF5,NEU3,GHR,KDM2B,HTATSF1,ZNF782,FUT10,EML4,TMEM25,GUCY1A2,IRAK3,RASSF8,UBE2QL1,FRMD5,HNMT,ZDHHC15,HSF2,SMAP1,EID2B,ZNF546,NKD1,DOCK7,SCIN,IL6ST,JAK1,JAK2,KCND2,KCNMA1,KIT,SYTL4,MAP4,MARK1,MAT2A,SYT9,LDLRAD3,MDM4,MEIS1,MEIS2,SRSF12,MIA2,AFDN,COL28A1,ADAM22,IDNK,NEFM,NF1,CNOT4,NPTX2,NRCAM,NUCB2,ETFRF1,PDGFRA,NALCN,PIK3C2A,A2ML1,NLE1,PLCL1,RC3H2,SDK2,ING3,EPB41L4B,PPP2R5E,GRAMD1C,RELN,SNRK,WDR25,CNTLN,ANKHD1,ELOVL2,PTPRD,MARCH1,CEP97,ATG16L1,DBX2,ZDHHC14,ERI2,SEC61A2,RIC8B,CCDC82,SETD5,EXD2,CARF,ROBO1,CCDC102B,BAALC,ZC3H14,LRRK2,CNTNAP3,KCNIP1,FAM192A,AMER2,TNFRSF19,ELMOD1,TRA2B,KIF16B,MAGI3,ST6GAL1,CNKSR2,NLGN1,CTXN2,RUFY2,KBTBD4,SPHKAP,SMARCE1,LIMCH1,SNCA,TRERF1,KDM3A,SP4,HECW1,KDM4C,TROVE2,ELOVL4,KANK1,SULF2,STXBP1,AJAP1,ACSBG1,PRRC2C,VPS13A,DNAJC9,SYT1,COBL,ANKRD28,DDHD2,TBCEL,EHBP1,ACSL6,SATB2,ZFP90,ZEB1,TRIM2,TCF12,FRYL,TEX15,RNF216P1,LEFTY2,HHIP,SLC44A1,NR2E1,FAM124A,CSMD1,C5orf64,NPL,KCNE5,TSC1,SSBP2,UBE3A,PLEKHH2,MEAF6,P2RY12,GUSBP1,TRIM9,ZNF177,EVI5,TMEM178A,VPS35L,FAM13C,PHTF2,NLRP3,NHSL1,NETO1,SLC4A10,SENP7" MicroRNA hsa-miR-545:PITA hsa-miR-545:PITA_TOP PITA 2.94E-90 1.65E-86 1.56E-89 1.44E-88 191 653 "FMNL2,GALNT13,USP31,INTS2,KLHL13,PCDH19,OSBPL6,LRRC7,OGT,CDC42BPA,ANK3,APBB2,USP37,NCOA1,DDX3Y,ATP2A2,MTMR9,BCL2L2,JAZF1,CDK5R2,LDLRAD4,CACNA1E,CACNB4,HAP1,CAMK2A,CAMK2G,INA,DCLK1,CCPG1,CFL2,SOCS6,CHN2,NRXN3,CLCN4,QKI,HECTD1,AKAP5,SLC4A7,MAGED1,IGDCC3,LRIG1,CSNK1G3,NCAN,ERC2,APPL1,CTNND2,ARHGAP24,HDAC4,TOX,PHF19,KIAA0513,GIT2,SPATA2,ELMSAN1,MYEF2,CEP170,ALKBH8,SMG7,G3BP2,USP3,CPEB2,DRD1,PDCD6IP,ABCC5,EDNRA,KMT5B,EGR3,GOLGA7,EIF4G2,PLEKHA1,ELAVL3,PAN3,RCAN2,EPHB1,EPS8,ETV1,ACSL4,ATP8A1,MED12L,AMOTL2,MEX3B,AFF2,SYT3,TACC2,SORBS1,SARAF,TBR1,CAB39,ILDR2,ARFIP1,GHR,GNAO1,GPD1,GPD2,TDRKH,GRIA4,NR3C1,CIT,TMEM25,BACH2,HNRNPK,HTR2A,OLFM3,KCNA6,KCND2,KLC1,ARHGAP12,SMAD1,MARK1,MBNL1,CHIC1,LRP1B,NEXMIF,NFIX,NRCAM,PCMT1,PRTG,PDE3B,PDE4D,ENPP2,PDPK1,SERPINE2,PIK3R1,LRP12,PPP3CB,RASGEF1B,RELN,PTCH1,MTMR10,PTPRD,TMEM255A,USP47,ARID4A,DBX2,RBBP6,RDX,TTLL7,ZFHX4,ZNF532,SGSM1,RMI1,PRCD,SCP2,PPM1E,CPEB3,DOCK10,NTNG1,CHD9,R3HDM2,SLITRK3,FAM214B,SLC11A1,CPEB4,SNAP25,PALLD,FAM219A,SON,MYT1L,KIF21B,CDK19,TAB2,ZNF621,LARP4,TTBK2,STAC2,SYT11,SYN1,SYP,SYPL1,CAMTA1,ADGRL3,TBL1X,DICER1,ZFPM2,AP4E1,ENHO,ZFP91,TP53BP1,TPM4,WBP2,TSC1,CADM1,FLRT2,ZBTB14,ZIC3,NDRG4,REEP1,CA10,HNRNPA3,RNF146,SENP7" MicroRNA hsa-miR-2115:mirSVR_highEffct hsa-miR-2115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.65E-90 2.05E-86 1.94E-89 1.79E-88 233 975 "ACADM,ACLY,CSMD2,NDRG3,FZD9,SNX32,CC2D2A,PPFIA1,PKP4,APC,UPRT,DDO,AMER3,SHTN1,ARNTL,LINC00173,ATP2A2,ATP2B2,ATP6V0A1,ADAM23,TTLL9,CACNB2,CACNG1,CALB1,CALB2,KALRN,VSTM2A,CARS,ZNF501,CCNH,DLGAP2,SYNPR,NRXN1,CLU,CLTA,CLTB,NGEF,NIPBL,BTF3L4,SLC4A7,RCHY1,BAG4,CP,CHD1L,SNCAIP,CSNK1G3,CST3,GREB1,NRSN1,RUBCN,CENPL,GIT2,ARMCX4,ARMCX2,YTHDC1,ZEB2,CEP170,RHOBTB1,ZNF582-AS1,HS3ST2,DMTF1,DRP2,ABCC5,DNM1L,EBF1,PHF20L1,TMEM132E,ASB3,COPS4,PCOLCE2,CALCRL,CDKL3,DNAJC27,WAC,TOMM40L,FKTN,FDFT1,OLFM1,AMOTL2,FHL1,POLK,SUCO,JKAMP,UFM1,PDLIM5,STAMBP,ZNF512,GABRA2,GABRB1,AHCYL1,JPH4,ERAP1,DISC1,LRRC37A6P,SULT1C4,SESN1,COPS8,PCDH11X,ZNF638,WDFY3-AS2,GPD2,LPAR4,GPR37,PCLO,RAPGEF4,GRIA4,PLCD4,GRM7,MIER3,LRRCC1,DISP2,USP54,DIPK1A,KCNA2,KCNN2,KIFC3,STXBP5,LAMP2,PAXBP1,HECTD2,MARK3,MDM4,MXI1,LYRM9,NACA,NASP,NCAM1,NEUROD2,NFE2L2,OCRL,ODF2,PCDH8,PDE1A,PDE2A,PDGFRA,ENPP2,PFKFB2,PIK3C2A,GPSM2,ST8SIA5,JAKMIP1,PCDH18,RC3H2,PSAT1,PPARA,PPM1B,PPP3CB,RASGEF1B,PKIA,MAPK9,APTX,SIDT1,PTK2,PEX2,ARID4A,RDX,SEC61A2,TMLHE,CARF,ROM1,RORB,ELP2,CCDC102B,ACER3,KCNIP1,RYR3,ATXN2,SCN2A,SMPD3,SGK1,SH3BGR,ITSN1,ST6GAL1,ST3GAL3,PAAF1,PPP4R3A,SMTN,SLC8A3,ARHGEF40,SLC9A5,BTBD7,EPC1,RCOR3,ANKRD36,PALLD,SON,SOX5,ENKUR,IQSEC2,NPAS3,ZC4H2,NKAIN2,SS18,ERBIN,DIP2A,ADHFE1,VPS13A,ADAMTS17,ATP11A,CAMTA1,SATB2,TCF7L2,USP22,WDR7,PCDHB4,TEX15,ZFPM2,SLC44A1,MTMR14,ZFP91,TMPO,NPL,CHST5,RGMB,PRMT8,TRO,ZMYND8,RPL7L1,CCDC136,MEAF6,WIPF1,GUSBP1,XRCC4,MICU3,UPF3A,CADM2,CSDE1,PCDH15,NAV3,NELFE,FAM13C,ADAMTSL3,CBLN2" MicroRNA hsa-let-7c*:mirSVR_highEffct hsa-let-7c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.91E-90 2.19E-86 2.08E-89 1.91E-88 231 959 "DPF1,RALGAPA1,ACADM,CLK4,CSMD3,GALNT13,ADD3,SLC24A4,GPR158,LRRC7,SEMA6A,ALCAM,SRPX,ABCD2,MAP4K3,PHF12,PPFIA1,ALS2,MIER1,ASPH,NUMB,ATM,RNF182,CADM3,DPY19L3,BACH1,SEC11C,NRP2,SYNJ1,CACNB2,CALB1,LRBA,CDH10,TIGD7,MS4A7,SYNPR,CNOT8,PPT2,QKI,SULT4A1,FAM171B,CREM,SLC32A1,ARHGEF10,OSBPL3,NCAN,SOCS5,VAC14-AS1,PHACTR3,KIAA0040,ERC2,PHF14,PUM1,ZSCAN23,NOS1AP,KIAA0408,ARHGAP32,ARHGAP24,LONRF1,KIAA0586,GIT2,PITPNC1,ZEB2,CEP170,MAGI2,ZC3H11A,RHOBTB1,SPOCK3,SV2A,DMD,NR1D2,CPEB2,HIPK3,SH3GLB1,EFNB3,FAM13A,PHF20L1,MBNL2,KMT5B,ELN,VPS13B,TMEM74,F5,F8,NSRP1,FCGR1A,FCGR1B,SLC9B2,FGF12,FGF14,SEC23B,DCTN2,UFM1,ZNF605,ZNF512,FYN,ARPP21,ERAP1,DISC1,SESN1,GHR,SPIN1,GLS,CBX1,FERMT2,RAPGEF4,GRIA1,GRID1,GRIK1,GRM5,ZHX1,HMGB1,ZIC5,ZNF385B,JAK1,OLFM3,VWA5A,HECTD2,SMAD1,EFHB,MDM4,MEIS2,MIA2,XRRA1,MN1,ZNF680,ZNF92,NCAM1,NEK1,NF1,SLC11A2,HCN1,NTRK2,OMG,CLDN11,OXTR,PDGFRA,BEST3,RETREG1,PLCL1,JAKMIP1,PLP1,PURG,LRP12,SPATA6,SLC36A4,POU3F2,POU6F1,LRRN3,PRKACB,SNRK,MDGA2,MTMR10,PTHLH,PXK,PTPRB,OCIAD1,PTPRD,PTPRG,KHDRBS2,SLC6A15,UBR7,SEC61A2,ZFHX4,ROBO2,ZNF354C,SEMA6D,ATXN7,FNIP1,ZFP2,IL17RB,PEAR1,CASC3,ITSN1,SH3GL2,FNDC3A,CTXN2,SEC31A,EPN2,DHX30,EFHD1,BTBD7,TET1,SORCS3,MYO16,SOX10,SP2,IDI2-AS1,CLASP2,SAMSN1,SMOC1,ERBIN,ELOVL4,PLCB1,CAMSAP2,KLHL4,PCDHB15,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,TEK,SLC44A1,BHLHB9,ZFP91,R3HDM1,NPL,HIRA,ZNF610,PITPNB,CCDC14,CLDND1,NPDC1,RICTOR,SMARCAD1,GDPD5,PRDM10,VPS35L,FAM13C,AMN1,UBE3B,KAT6A,PHTF2,IFT88,SOCS4" MicroRNA hsa-miR-135b*:mirSVR_lowEffct hsa-miR-135b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.29E-90 2.97E-86 2.81E-89 2.59E-88 246 1085 "SERPINA3,ABCF1,NBAT1,SYS1,CSMD3,TMEM132B,GALNT16,ADCY6,RNF157,ADD1,SORCS1,ADORA1,PTCHD1,NLGN4X,SORCS2,SEMA6A,MARCH4,UNC79,AMPD3,AMT,ZFAT,LRCH2,APLP1,UPRT,APOC1,AMER3,AQP4,MIER1,CADPS,ASCL1,DYNLL1,TMEM108,ATP2B1,ATP2B2,NOL4,MPDZ,NRP2,CFLAR,BMP7,CDK5R1,ARHGEF7,JAZF1,CACNA1A,TRIM41,CAPN3,KYAT1,SEPT7,EVI5L,CDO1,CACNA2D2,SRSF11,CHN1,RAB33A,RAB28,IGFBP7-AS1,TPP1,STOML1,CNN3,ARMC8,RTTN,FAM171B,CRY2,SNCAIP,RGS6,SEC24C,CSNK1G3,ATRNL1,CNTNAP2,CMTM5,ST18,KIAA0408,DCAF8,HDAC4,EARS2,ZNF337,PHYHIP,ARMCX4,JAKMIP2,CEP170,KLHL3,SNAP91,SGSM2,CCDC3,ACOT8,DRP2,DTNA,ECM2,ABCC9,PHC2,SGK2,HIPK3,KLHL5,PHF20L1,EGFR,MBNL2,RASA4,C8orf37,RABEPK,SRRM1,CEP85L,ETV1,RASL12,ABCA8,FCGRT,STRADA,ZNF589,GTF2IRD2,POLR1B,FGF11,FGR,AGAP2,JKAMP,NPTN,CAMKK2,TMEM151A,ABLIM2,STAG2,GABRB3,ILDR2,DISC1,NEU3,TUBGCP4,GFER,FREM1,TOX3,KCNMB4,GNG4,PRUNE2,CECR2,CNTRL,GRM2,PRDM5,GRM7,LINC00839,GSTT2,SLC2A6,PADI2,HRH3,ELOVL5,NEGR1,LRRC75A,LINC00667,LRRCC1,IL6R,ITGAV,KIF5C,STMN1,HECTD2,GPR155,MARK3,MATN2,MBNL1,LDLRAD3,MN1,MOBP,SESN3,BCO1,NDUFA5,CCDC13,NRGN,HCN1,IGSF11,OPHN1,PFKFB3,NLGN3,PIK3C2A,ANLN,ST8SIA5,PLCD1,LRP12,MAPK4,MAPK9,GRAMD1C,PIGG,CNTLN,TMEM260,PTPRB,CASTOR1,USP47,GTDC1,ZDHHC4,RGR,SUGCT,CARF,ROBO2,TMEM206,ADAL,TCP11L1,ABCA11P,ST6GALNAC6,NCBP3,TRAPPC13,ATXN2,SCP2,TNFRSF19,SOX6,MRAS,TRA2B,KIF21A,DHX30,SLC6A7,ATF7IP,ANKRD36,SNCA,UNC80,ZCCHC24,BDP1,SPART,TAB2,TROVE2,ITPRID2,ZNF302,ZC4H2,SEPT8,RHBDL3,VPS13A,EHBP1,VWC2,CLASP1,OBSL1,FRYL,CYB561A3,SIRT1,CRB1,THRA,TJP1,ERCC6L2,SEZ6L,TPM3,ZNF384,RGMB,SYNPO2,PRMT8,UBTF,ZNF23,ZBTB38,FSTL5,ZFAND5,PRTFDC1,DNALI1,SLC38A1,PRDM8,PRDM10,SLC17A6,KAT6A,ST8SIA2" MicroRNA hsa-miR-145*:mirSVR_highEffct hsa-miR-145*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.93E-90 3.33E-86 3.15E-89 2.90E-88 232 969 "KCNH8,NCKAP5,CSMD2,XKR4,NDRG2,AXIN2,SNX32,PCDH19,TXNDC16,AK2,CEP126,DPP10,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,GPAM,ZBTB10,NCOA1,NUMB,ATP2B1,N4BP2L1,NOL4,ATP6V1G2,ADAM23,TTLL9,BACH1,ADGRB3,CFLAR,KALRN,CAMK2G,TRIM41,SLC25A14,USP6,LRBA,CDC27,QKI,NIPBL,LETMD1,SLC4A8,RTTN,RNF14,SLC32A1,NCOR1,CS,CTNND1,PUM1,RIMS2,CYBB,DOCK4,KIAA0586,PITPNC1,C8orf34,KLHL3,BLOC1S6,DDX46,RHOBTB1,SMG7,PLPPR4,NTM,G3BP2,WDR20,RAB39B,USP3,FAM57B,DYRK1A,ABCC5,AASDH,EBF1,FCF1,FSD1L,KMT5B,EGR3,TNK2,ELAVL4,EIF1,COQ7,RCAN2,KCNMB2,ENPP6,DNAJC27,FABP7,CHST15,FCGR3A,CAP2,PSD2,FOLH1,NRG3,GABRA2,HRASLS5,ZMYND11,B4GALNT1,ARPP21,GHDC,ERAP1,DISC1,IGSF5,GCNT2,GGTA1P,GGT7,PPARGC1A,MALT1,RAB30,GLS,GPD2,GPR22,GRIA1,GRIA2,GRIK2,GRM7,RNF165,PSIP1,GUCY1B1,IRAK3,NXPH2,TCEAL6,SMAP1,ZNF181,C5orf24,RBPJ,ZNF385B,LRRTM1,KCND2,KCNJ3,MAN2A2,KITLG,AFDN,MOBP,MPP2,ZNF680,MSR1,MTTP,MYO7A,MYO9A,NELL1,NEUROD1,NUCB2,ODF2,OLR1,OXTR,SNTG1,ETFRF1,PIRT,PDGFRA,GPR85,GNG2,BEST3,ZNF655,RETREG1,GPSM2,PURG,EPB41L4B,PCDHB17P,PKIA,GRAMD1C,MASP1,PLPPR1,PTPRD,TTC13,ACSS3,CCDC40,RAD52,FAM184A,MSANTD2,PCMTD2,MRAP2,SNX22,BAALC,AP1AR,RMI1,SEC14L1,KIF27,ITSN1,NTNG1,MAGI3,FHOD3,FAM81A,SLC1A7,SLC2A5,RUFY2,KANSL3,SLC8A3,CCDC88A,BTBD7,COA1,RCOR3,MYO16,USP33,DOP1A,KDM3A,KDM4C,KIF1B,SPART,CLASP2,NKAIN2,TTBK2,SULF2,GANAB,PRRC2C,VAMP1,VPS13A,COBL,DDHD2,CAMTA1,MCF2L,FAM208A,ZFP90,TCF7,RALYL,USP32P1,ARHGAP9,AHCYL2,TK2,ZFP91,ERCC6L2,R3HDM1,TPM1,NEIL2,ANKRD20A2,SSBP2,VLDLR,RICTOR,MKRN3,SYNC,UPF3A,PCDH15,MVB12B,FAM13C,ACTR3B,RNF170,NETO1,SOCS4,SENP7" MicroRNA hsa-miR-3194:mirSVR_lowEffct hsa-miR-3194:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.84E-90 4.40E-86 4.15E-89 3.82E-88 289 1471 "VWA5B2,CPNE2,TTYH1,KCNH8,EMILIN3,NDRG2,UNC5A,MTA3,KIAA1324,SYT13,AMPD3,MAP4K3,USP28,PPFIA4,CNIH2,PPFIA3,LGR5,PRX,TMEM263,MARK4,CCAR2,TMEM108,CHID1,ATP1A3,N4BP2L1,NOL4,ADAM15,RGS11,BID,KSR1,JAZF1,AP1M1,MMD2,CA8,CA12,CACNA1E,CALB2,CALM1,CAMK2B,CAMK2D,TRIM41,CAPN3,SPAG9,CBR1,P2RX6,AIFM1,CDC27,NUMBL,CHI3L2,TAOK2,FBXO7,HECTD1,PCYT1B,SMARCAL1,MFSD4A,CREM,AATK,SNCAIP,CSF1R,RGS6,CSNK1E,ATRNL1,GALNT9,CST3,SDC3,ARHGEF4,NRSN1,GPSM1,NOS1AP,DCAF8,TOX,DGKG,TMEM130,LYPD1,POM121,SV2B,G3BP2,HS3ST2,SLC29A4,DPH1,SLC25A18,DTNB,TOM1,DNAJB6,ABCC5,EDNRA,SYT15,CNNM1,HEYL,SIDT2,SUGP2,APH1A,MRO,RASA4,ELAVL2,TNK2,ANKRD13B,CDHR1,MRPL37,ADGRV1,EZH1,FABP7,FCGR1A,FCGRT,FGF1,BAIAP2,FGR,HPCAL4,NOP56,ARFGAP2,DACH2,KBTBD12,SDCBP2,GALNT15,BRPF3,ATP8A2,INPP5K,GATM,SRCAP,SULT1C4,ARFIP1,GHR,KIRREL3,RND1,GLI2,STARD3,LILRA2,RAPGEF4,PLCD4,ADAMTS13,SERP2,RNF165,RABL2A,RNFT2,FRMD3,FAM95B1,MYLK2,RBPJ,TJAP1,ZNF678,LRRTM3,KCNF1,KCNJ10,KCNJ11,KCNMA1,KLC1,LMO1,LSS,ASPRV1,SYT9,SCAMP5,AFDN,BLOC1S2,NRBP2,N6AMT1,MXI1,LAYN,HNRNPM,NASP,NF1,NOVA1,DNHD1,NPTX1,NPTX2,IGSF11,OGDH,OPCML,CDK18,PDE1B,PFKFB4,CDK14,PHKG1,FAM216A,SLC25A23,PLXNB1,PLXNB3,C11orf49,EXOSC10,RETREG2,POLG,SH3KBP1,CRLS1,PTPA,NKAIN4,PPP5C,RASGEF1B,PRKACB,PRKCB,HYDIN,MASP1,MDGA2,ZSCAN32,PTPRG,PTPRN2,FAM120C,RIPOR1,NKAIN1,TUG1,CEP97,CCDC40,RAD51D,RALGDS,SUSD4,ARHGEF10L,ZFHX4,ZNF532,TMEM206,ADAL,SYNDIG1,KCNIP3,KCNIP2,RTN1,ZNF568,MAPK12,SATB1,CSRNP3,HOGA1,SCN4B,PRCD,SCP2,TNFRSF19,ASIC4,SH3GL2,MYO18A,NTNG1,NLGN1,ST8SIA1,RPH3A,SLC6A7,ARHGEF40,SCMH1,SMARCD3,INTS9,ANKRD36,RIMS1,SNRPN,TNIK,BDP1,ZSWIM8,NKAIN2,LRRC4,NCDN,MPRIP,KLHL7,SUPT5H,ZFR2,ADAMTS17,ARC,MMS19,TACC1,PDLIM2,SMG6,EHBP1,TPCN2,RPGRIP1L,WDR7,DOCK9,AKNA,TNS2,VWCE,AKTIP,GALNT17,ARL10,NACC2,TLL2,TPM1,TPM3,C9orf85,ZNF384,SMUG1,TRPM2,TMPRSS5,LAT2,WRN,LGI4,ZNF19,TRIM9,CRB2,POLR3H,AMZ1,FTSJ1,SLC30A3,RNF103,WIPF2,HNRNPA3,CAMK1G,NUP214,FXR1,JPH3" MicroRNA hsa-miR-645:mirSVR_lowEffct hsa-miR-645:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.38E-90 4.71E-86 4.44E-89 4.09E-88 238 1020 "SERPINA3,EMILIN3,NBAT1,GALNT13,PWWP2A,KIDINS220,KLHL13,TBC1D14,WDR35,PLA2G6,ALAD,USP35,SUGT1P4-STRA6LP-CCDC180,ANXA7,APC,BCAS1,LGR5,MIER1,CADPS,MARCH3,ZBTB10,DDX3Y,DYNLL1,ATM,ZNF583,SLC2A11,ALDH7A1,NOL4,BBS2,BMP7,BMPR1B,SCAPER,SGCE,RAB29,CA8,MAP7,INA,C1orf52,CASC2,PPT2,FAM19A5,QKI,SRP14-AS1,NIPBL,COL4A5,SLC4A8,CNRIP1,RBM39,AKAP12,CRY2,SNCAIP,CSNK1G3,IPCEF1,PDE4DIP,SLITRK5,RIMS2,CYBB,KCTD8,DGKB,DGKG,DBN1,SPATA2,ZBTB24,SPOCK3,CD99L2,DMTF1,SLC25A18,DRP2,DNAJB6,ABCC5,E2F5,E2F6,EDN3,HIPK3,CNNM1,RASGRP1,SH3GLB1,PHF20L1,USPL1,VPS13B,EPB41,RASL12,FAM198B,ACSL4,PTK2B,RACK1,FKTN,TESK2,ZNF589,SEC24B,GTF2IRD2,UBE2E3,EVL,COQ5,C2orf88,APOPT1,ATP2C1,DACH2,PNMA2,GAB1,FAM120B,KIAA1841,GCK,SESN1,TCERG1,GLUL,ADGRA3,PRUNE2,LPAR4,GRB10,GRID1,CIT,MFSD2A,FRMD5,MAN1B1,MIER3,HLF,HMGCL,HNMT,ZDHHC15,ATCAY,IGFBP1,NKD1,NME9,KCNC2,KCNJ10,LMO2,GPR155,MAT2A,LRP1B,MEF2C,THYN1,NEUROD1,NFIA,NFE2L2,CNOT4,LRIT2,SLC11A2,SMIM11A,SETD4,TBC1D25,OPCML,OPHN1,PDCD2,CCSER2,PMP2,TNPO2,MED1,PPM1B,MAPK9,MAPK10,BCAS3,VPS13C,PPP2R3C,ZDHHC14,BSDC1,RFX3,PRIMA1,MRPS18A,RIC8B,ALG9,YY1AP1,SPIN3,KIAA0895L,PTGR2,S100B,SEMA6D,SATB1,LRFN5,HOGA1,SCN7A,PRCD,CASC3,MRAS,PPM1E,AMBRA1,ST3GAL3,PEX26,DHX30,SLC8A2,RAB3GAP1,SLC11A1,SLC20A2,ATF7IP,RIMS1,DOP1A,BDP1,ZSWIM8,PEG10,SPART,ATP10B,CLSTN2,POGZ,COLGALT2,ITPRID2,INKA2,CEP68,DIP2A,ADHFE1,SYT11,SUPT5H,SLC37A2,POPDC3,TCF7,NAT16,DICER1-AS1,ZFP91,TNFRSF1B,C5orf64,RASD2,ZNF346,TRH,RUSC1,TTTY15,RFTN2,FAM181B,MEAF6,CLIP2,LAT2,TRIM9,MKRN3,ZNF138,ZNF142,ZNF154,PLPPR5,ZNF213,MEIS3,UPF3A,SHD,GDPD5,SEMA3B,FAM47E,SMIM8,ADAMTSL3,SNX14,IFT88,NETO2,PRRT4" MicroRNA "AAGCACA,MIR-218:MSigDB" "AAGCACA,MIR-218:MSigDB" MSigDB 1.49E-89 8.36E-86 7.87E-89 7.25E-88 146 370 "ASIC1,ACTN1,CSMD3,GALNT13,SORCS1,SLC24A4,CASKIN1,KCTD16,LRRC7,SEMA6A,SYT13,PKP4,GPAM,SHTN1,ARHGAP5,NUMB,DPY19L3,ADGRB3,SYNJ1,CACNA1I,KALRN,SPAG9,FOXN3,SOCS6,CHM,NRXN3,NRXN1,NMT2,HAPLN1,RIMS4,PUM1,ST18,GAPVD1,RIMS3,DBN1,ELMO1,MAGI2,PLPPR4,SACS,SV2A,HS3ST2,FAM13A,MBNL2,GOLGA7,EPB41L1,ANKRD13B,RTN3,MED12L,B3GAT1,NEURL4,GABRB3,BRPF3,FREM1,PPARGC1A,GNAO1,GNG3,GPM6A,GRIA2,GRIK2,GRIK3,NR3C1,GRM1,RNF165,TMEM25,GUCY1A2,KLF12,HLF,ELOVL5,SHISA6,PLD5,SCRT2,BRINP3,OLFM3,KIT,LIFR,HECTD2,MBNL1,SCAMP5,MITF,MDGA1,NFIX,PCDH8,PDGFRA,GPR85,ZDHHC8,PIK3R1,TRHDE,PPP2R2C,PTPA,KANSL1,DIRAS2,RELN,MDGA2,ZMAT4,RET,RNF220,ROBO1,ROBO2,RPS6KA2,LGR4,ATAT1,ATXN1,ATXN2,SEC14L1,SHC4,FHOD3,ABLIM3,SLC1A2,SLC6A1,CCDC88A,SHANK2,SLC12A2,SOX5,KIF21B,SOX11,LMO3,MAPK8IP3,STXBP1,C3orf70,TAC1,TACC1,ANO4,TBX15,SATB2,ARHGEF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,ZFP91,RIMBP2,UBE2H,RICTOR,TRIM9,NDRG4,CSDE1,GDPD5,RNF103,NAV3,ITM2C,RTN4" MicroRNA hsa-miR-651:mirSVR_highEffct hsa-miR-651:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-89 9.29E-86 8.74E-89 8.05E-88 245 1082 "RALGAPA1,ACADM,ACTN2,SLC25A25,SLITRK1,BRAP,SORCS1,PLEKHH1,MTUS1,OSBPL1A,LRRC7,PCDH10,PPFIA1,APBA2,GPAM,AQP4,ARNTL,ARRB2,ASCL1,BRINP2,DDX3Y,SLC4A4,ZNF582,ADGRB3,BMPR1B,SYNJ1,LINC00906,THSD7A,CALM1,VXN,CAST,SEPT7,MAGI1,CFL2,SRSF11,LHX2,IGFBP7-AS1,PLAA,CNTN1,ARMC8,FAM171B,CLOCK,ANKRD44,CLIP3,CSF1,ARHGEF10,CSNK1G3,CTNND2,PUM1,CYBB,LONRF1,DBI,GIT2,ZEB2,ELMO1,FBXL5,CHRDL1,EXOG,DMD,GNE,ARRDC4,DNM1L,EBF1,EDN1,EDNRB,ANKRD46,SEMA3D,PHF20L1,ELAVL2,ELAVL3,RGS17,STARD3NL,C8orf37,KCNMB2,RCSD1,EFEMP1,FKTN,ZSCAN30,GORAB,MED12L,SUCO,FOXG1,SEC23B,DKK3,GABRA2,GATM,SULT1C4,SESN1,GHR,RAB30,CBX1,LNX1,GPR34,PCLO,ATP2B1-AS1,GRM5,FAM19A2,PSIP1,DHX35,HTR5A,ATCAY,RBPJ,KIAA1755,LRRTM3,SLC35G1,OLFM3,KCNC2,KCNK2,INSYN2,LMO2,HECTD2,ARHGAP12,MAP4,MBD1,PPM1L,AFDN,XRRA1,MXI1,MYCN,MYO7A,MYO9A,NFE2L2,NODAL,CNOT4,NRCAM,HCN1,NTRK2,GPR88,LOC100128398,PDCD2,PDE1A,PDGFRA,PDYN,GPR85,BEST3,ZNF655,FAM218A,GPSM2,HMGCLL1,MTRF1L,PMP22,TRHDE,PSAT1,MED1,PPP2R5E,PPP3CA,PPP3CB,PKN2,EPDR1,HYDIN,MASP1,VPS13C,MDGA2,PTPRB,EML5,PTPRG,MARCH1,CEP97,NWD1,ZDHHC14,SLC6A15,ERI2,RFX3,CARF,UEVLD,ATP8B4,GLDN,CNTNAP3,MEG3,TRAPPC13,FAM192A,SCN3A,LRRTM4,GALNT10,PPP1R9A,NTNG1,HKDC1,MAGI3,SLITRK3,CNKSR2,SLC2A5,CCDC88A,SLC12A2,MTERF2,EFHD1,SPHKAP,TET1,CPEB4,SORCS3,SNRPN,SOX3,CLUAP1,EMC1,KDM4C,SPART,CLASP2,SSTR1,STXBP1,AJAP1,FGD4,PRRC2C,COBL,TACR1,SATB2,ZEB1,TMEM151B,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,BEX4,RBFOX2,C9orf85,TPM4,SYNPO2,TRH,STXBP4,CLHC1,CADM1,UBE2H,PLEKHH2,VAV2,CCDC14,WIPF1,ZNF28,FMN2,FSTL5,ANKS1B,SYNC,SLC30A4,PRDM2,RNF103,ADAMTS9,NAV3,TMEM163,RGS7BP,GOPC,FZD3,PAK5,ADAMTSL3,SLC4A10" MicroRNA hsa-miR-600:mirSVR_highEffct hsa-miR-600:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-89 1.14E-85 1.07E-88 9.83E-88 229 950 "SYS1,BEND6,KLHL13,AK2,ALCAM,SYT13,LCORL,MAP4K3,ANXA7,ALS2,SHTN1,RASL11B,NOL4,ADAM23,DST,SYNJ1,PTBP2,CCK,INA,AP4M1,MAGI1,CDO1,CCPG1,SRSF11,ZBED5,KMT2C,EPS15L1,PPT2,SLC4A8,HAPLN1,ANKRD44,SNCAIP,RGS6,MICAL2,CSNK1G3,SLITRK5,DZIP3,RIPOR2,ARMCX4,ZNF804A,C8orf34,MYEF2,MAGI2,SMG7,SV2B,RABGAP1L,KBTBD11,ABI1,DTNA,ECM2,EDN1,FRY,EFNB3,PHF20L1,KMT5B,KCTD3,MRNIP,EPB41,EPHA5,SRRM1,EPS8,RCSD1,RRAGB,ABCA8,RPS6KC1,DLC1,CEP78,FGR,FOXG1,C2orf88,NBEA,ATP6V1H,ERGIC3,ST6GALNAC3,GAD1,AHCYL1,ARPP21,C15orf41,DISC1,SULT1C4,ARFIP1,SPIN1,ZNF638,GNAO1,FERMT2,ADGRA3,GRIA2,PRDM5,GRM7,COQ10A,PSIP1,GUCY1B1,MAEL,RASSF8,TOX2,ZHX1,HSP90AA1,IGFBP1,RBPJ,ZNF385B,ITPKB,KCNA4,KCND2,STMN1,PAXBP1,NCOA7,MAP2,MAT2A,MBD1,MDM4,MOBP,BEX5,NASP,NF1,OTOGL,NOVA1,HCN1,NUMA1,OLR1,PCDH8,PCSK1,PDE4A,PDGFRA,RETREG1,PLCB2,ST8SIA5,FTO,PRRX1,SDK2,ING3,CRLS1,PPP2R5E,PPP3CA,PPP3CB,CEP41,HYDIN,DIRAS2,KLK6,PTPRD,PEX2,PEX5,CEP97,RFX4,RPRD1A,KLHDC8A,CARF,ROBO2,PCMTD2,ATP8B4,CSRNP3,ATXN7,SGK1,NTNG1,FAM81A,CCDC88A,EFHD1,SLIT1,RCOR3,MYT1L,ZSWIM8,GLT8D1,ZC3H13,BEX1,C11orf87,TAB2,CLASP2,ITPRID2,ERBIN,ST5,NEK4,DIP2A,SEPT3,FGD4,SYNE2,SYPL1,UNC5D,KLHL4,EHBP1,TCF4,KIAA0930,TCF7L2,TRIM2,TCF12,USP22,SZT2,SYNE1,PCDHB9,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,VWCE,ARL10,TMPO,BEX4,TNS1,TPD52,METTL3,TMEFF2,SGK3,FAM155A,UBE3A,UCHL1,MEAF6,WRN,RICTOR,ZIC1,LYPD6,ANKS1B,FTSJ1,EMSY,PRDM2,STOX2,PCDH15,MPPE1,AMN1,FZD3,KAT6A,SMIM8,PHTF2,CBLN2,SLC4A10,CPNE4,LAS1L" MicroRNA hsa-miR-31:mirSVR_highEffct hsa-miR-31:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-89 1.15E-85 1.08E-88 9.92E-88 219 870 "CLK4,NCKAP5,KDM5D,ARID1A,NDRG3,SLC12A5,DPY19L2P4,OLMALINC,AGT,RTL9,USP28,PHF12,APP,CDK13,NUMB,CCAR2,DPY19L3,JAZF1,WASF1,THSD7A,CAMK2D,TRIM41,RUNX1T1,MTMR7,INA,DGKI,ARHGEF2,SRSF11,ASIC3,CLCN3,TJP2,QKI,AKAP7,IQCK,SLC25A27,SLC4A8,PREPL,CSF1,TENM4,MICAL2,PDE4DIP,CTH,CTNND2,GPSM1,ST18,EDRF1,CYBB,HDAC9,ARHGAP32,DCAF8,TM9SF4,PABPC5,ZNF804A,RHOBTB1,G3BP2,DPP6,E2F6,FAM135B,EDNRB,FSD1L,EZH1,CACNG3,ACSL4,FCGR1A,TESK2,SPSB4,POLK,TACC2,SPECC1,APOPT1,KHDRBS3,ST6GALNAC3,B3GAT1,ZNF512,GABBR1,GABRA2,CAB39,AHCYL1,DNER,SULT1C4,GLI2,TOX3,TNRC6A,DIPK1C,GRM7,PTPN5,RABL2A,SOX21,MAP4K5,RASSF8,NXPH3,LINC01102,BACH2,VSIG4,HMGCL,SHISA6,ITGAV,KCNA6,KCNK2,C2orf80,PIK3AP1,ZNF667-AS1,MAP4,MEST,MOBP,CPNE9,CTNNA3,MYH6,NF1,ALDH1L2,HCN1,IGSF11,GPR88,OPRL1,TREM2,PC,BEST3,CYTL1,GDAP1L1,PIK3C2A,A2ML1,SNX10,RETREG1,EPB41L4B,SH3KBP1,PRKACB,PRKCB,HYDIN,SAMD9,VPS13C,STK32A,OCIAD1,TMEM145,PEX5,ZNF615,RAB5B,RET,PRRT2,RGS4,RIT2,ZFHX4,GSTCD,CCDC25,MRAP2,ATAT1,SEMA6D,ATXN2,SCN2A,ASIC4,ELMOD1,TRIM46,ZFP30,PPP1R9A,FERMT1,SHC4,FNDC3A,ST3GAL3,WDR37,RPH3A,BTBD3,WDR47,SEPHS1,SLC8A3,ARHGEF40,CDK5RAP3,KBTBD4,ATF7IP,FAM126B,PDZD2,MYT1L,TNIK,SP2,PEG10,LMO3,C11orf87,CLASP2,ZNF302,NKAIN2,NXT2,PHLDB1,KANK1,NSFL1C,FGD4,JMJD6,POPDC3,KAZN,TAF9,EHBP1,SATB2,TCF12,RALYL,TEK,DICER1,CRB1,TLR4,FAM124A,CSMD1,TNS1,IL34,ZNF384,SMUG1,FNDC5,KCNE5,TSN,RFTN2,OSBP2,WIPF1,ZNF19,ZNF540,ZNF74,GPR158-AS1,SYNC,WNK1,EMSY,CIAPIN1,PDSS2,FZD3,ST7,ZNF248" MicroRNA hsa-miR-4269:mirSVR_highEffct hsa-miR-4269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-89 1.18E-85 1.10E-88 1.02E-87 200 725 "KCNH8,CLK4,CSMD2,ADCY2,CCDC85A,SLC12A5,AP2A2,ZNF608,SMIM17,PCDH10,ALK,AMPD3,LRFN1,LRCH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,APP,DOCK11,BCL7A,GPR146,BTK,CACNA1B,DDR1,CACNB2,KALRN,CAST,CLDN10,MAGI1,SRSF11,RAB33A,IGFBP7-AS1,CLCN3,FBXO7,AKAP6,ABI3BP,CSNK1G3,ATRNL1,PLXNA4,CX3CR1,GAPVD1,TCAF1,FRMPD4,ZFYVE16,DGKB,GIT2,DNAJC6,C8orf34,ZEB2,ZC3H11A,RHOBTB1,DLG2,NR1D2,DNM2,DTNA,FAM78B,DNM1L,SNX29,HIPK3,KLHL5,FAM13A,PHF20L1,EIF4G1,PLEKHA1,TNK2,GPHN,RTN3,ADGRV1,TAOK3,CEP78,ZNF589,SEC24B,SUCO,FOXM1,SORBS1,PRELID3A,FAM120B,C15orf41,NEU3,ALDH1L1,SPIN1,MSL3,POLL,GNAS,GOLGB1,TDRKH,PCLO,CLASRP,IL1RAPL1,RASSF8,HNF4G,ZDHHC15,HSF2,IGSF1,IL6ST,ZNF678,LRRTM1,ITGAV,SLC35G1,KCNC2,KCND3,KCNJ11,KCNK1,MAN2A2,MAP2,MAT2A,MBNL1,KCTD6,NAP1L2,NELL1,NTRK3,ZNF827,PCSK1,PDCD2,PDGFRA,CCSER2,SNX10,FAM216A,NXPH1,MINDY2,PPM1B,KANSL1,WBP1L,QRICH1,CNTLN,PTPRB,PTPRN,PTPRO,PPP2R3C,USP47,SH3TC2,NWD1,RASGRF2,RBBP6,KHDRBS2,DPF2,GTDC1,FIGN,PBRM1,KCNIP1,ATXN7,SCN2A,SCN3A,LINC00461,PRCD,SH3BGR,KIF21A,KIF16B,MAGI3,CHD9,SLITRK3,ST3GAL3,PAAF1,ABLIM3,ZNF365,WDR47,SLC8A3,ATF7IP,DOP1A,SRPK2,ZC4H2,SS18,ADHFE1,KANK1,SYP,C12orf76,ATP11A,MTCL1,DNMBP,PCDHB4,FRYL,AHCYL2,FAM200B,SIRT1,CDH22,SLC44A1,TMEM9,HEY2,PIK3R5,C9orf85,PRMT8,TRPC3,TRPS1,RPL7L1,UGT8,MEAF6,PCDH20,TRIM9,ZFAND5,MAP3K12,EMSY,CSDE1,ADAMTS9,MDH1B,NELFE,PDSS2,RGS7BP,RTN4,FAM219B,DPF3" MicroRNA hsa-miR-183:mirSVR_highEffct hsa-miR-183:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.43E-89 1.36E-85 1.28E-88 1.18E-87 217 855 "ABAT,NCKAP5,CSMD3,SLITRK1,OSBPL8,TXNDC16,LRRC7,ARHGAP20,OGT,PKP4,UPRT,GPAM,MIER1,LINC00173,ASPH,ASTN1,ATM,CDK5R1,SCAPER,RUNX1T1,TIGD7,SRSF11,CNOT8,RAB28,CLCN3,QKI,NIPBL,AKAP5,RTTN,CNRIP1,HS3ST5,CP,AKAP12,HAPLN1,CS,CSF1R,ARHGEF10,CCDC144A,BOC,RIPOR2,ZFYVE16,DBI,SIRPA,ARMCX4,C8orf34,ZEB2,RHOBTB1,SACS,DYNC1I1,DTNA,FAM78B,FARSB,TSPAN5,FAM135B,YAF2,PHF20L1,SUGP2,RCSD1,TLR7,F8,CLVS1,ABCA8,FAM198B,WAC,GORAB,TMEM164,SUCO,SCARA3,AGAP3,SEMA4D,UFM1,TRIM16,RASL10A,ATP2C1,CELF1,HRASLS5,ARPP21,NCKAP1,GART,TUBA8,SESN1,LYVE1,GLDC,GLUL,PCDH11X,KDM2B,GNAO1,FERMT2,GPM6A,GPR34,EML4,RAPGEF4,GRIK2,NR3C1,GRM1,PRDM5,USP51,ICA1,KCNC2,KCND2,KCNK2,KIF2A,HECTD2,MBNL1,MDM4,MEF2C,SRSF12,AFDN,CTNNA3,PABPC1L2A,NCAM1,IDNK,SLCO1C1,DNHD1,NRCAM,P2RX7,KCNK10,PDE3B,GPR85,GNG2,PFKFB2,PIK3R1,XRN1,RC3H2,ING3,EPB41L4B,PPP2R5C,PPP2R5E,PRKACB,MAPK4,MAPK9,GRAMD1C,HYDIN,MTMR10,TMEM260,EML5,PTPRE,PTPRG,PTPRZ1,PEX5,ACSM5,PPP2R3C,RASGRF2,RBBP6,KHDRBS2,TTLL7,SEC61A2,RAVER2,ROBO2,ELP2,CLIP1,AP1AR,SCP2,KIF21A,NTNG1,MAGI3,SLITRK3,SLC1A3,MTERF2,SLCO1A2,TET1,SORCS3,SMARCE1,RCOR3,TTC17,SNRPN,PALLD,PDZRN3,NPAS3,NFASC,LMO3,TAB2,ATP10B,POGZ,ERBIN,DIP2A,ADHFE1,AJAP1,ABCC8,SYN2,SLC37A2,EHBP1,TCF4,TCF7L2,ZEB1,TCF12,FRYL,ZFPM2,SLC44A1,TIMP4,ACTR6,TMPO,BEX4,RIMBP2,TPM1,TPM3,SYNPO2,SLAIN1,VLDLR,WRN,CLDND1,LGI4,ZIC3,ATP6V0E2,ZFAND5,DNALI1,TMEM178A,GAL3ST3,TRIM16L,PLSCR4,FAM13C,FZD3,PAK5,SMIM8,ZNF248,ZDHHC20,FRMD6" MicroRNA hsa-miR-331-3p:mirSVR_lowEffct hsa-miR-331-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.40E-89 1.91E-85 1.79E-88 1.65E-87 246 1094 "DPF1,SYN3,ASIC1,FAM43B,XKR4,GALNT16,SLITRK1,PNMA8B,NLGN4X,AP2A1,SEMA6A,AMPD3,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DGKZ,APOC1,CASK,ARNTL,ARRB1,MARK4,CADM3,NOL4,TTC9B,SNAI3-AS1,KSR1,DST,AP1M1,MMD2,CACNA1D,DDR1,LDB2,SLC5A11,USP2,DGKI,SEPT7,LRRFIP1,LARGE1,IGFN1,UBE2L6,LSMEM2,SLC22A6,TPP1,MYL6B,DGCR9,TJP2,DNAJB5,NIPBL,IGLON5,CNR1,ARMC8,COL11A2,MYRIP,GDA,MICAL2,ECE2,PHF19,PHYHIP,C8orf34,ZEB2,POM121,RHOBTB1,SV2A,KIF19,ZNF582-AS1,SLC25A18,FAM78B,PHC2,SIDT2,EFNA3,KMT5B,ABI2,ING4,ANKRD13B,ERBB2,NCALD,VPS26C,F8,WAC,CACNG3,TMEM132C,PTK2B,CHST15,TOMM40L,FCGRT,PRMT5,GORAB,FLNC,ZNF605,CELF1,TMEM151A,HBS1L,JPH4,ARPP21,ATP8A2,GFER,MMADHC,HEPN1,CRCP,PCDH11X,STARD3,POLL,KCNMB4,LILRB4,ADAP1,RAPGEF4,GRIA4,GRIK3,TMEM25,AP4S1,SOX21,ATXN2L,AGBL5,HPCA,HSD17B1,SMAP1,IRF8,MSL1,GAREM2,ZNF385B,LRRTM3,C2CD4C,ITPKB,KCNA6,KIF5C,LRRC4B,CAMK2N2,NCOA7,LSS,MAN2A2,MAP6,MEIS2,MPP2,MSI1,BCO1,PTOV1,NRBP2,LAYN,HNRNPM,P2RY13,NCAM2,NUMA1,CLDN11,PC,PDGFRA,NLE1,PLXNB3,C11orf49,POU3F2,FSD1,MINDY2,PRKAR1B,GRAMD1C,HYDIN,MTMR10,PTPRD,C1orf109,ZSCAN2,TTC13,MARCH1,RAB5B,GTDC1,RGS3,RGS12,TMLHE,PNMA8A,RPE65,EPHA10,STX1B,ATXN7,LRRTM4,LINC00461,TRIM46,CASC3,SH3GL2,MYO18A,HKDC1,CHD9,FNDC3A,RPH3A,FAM214B,SLC6A1,KANSL3,PKNOX2,SLC6A9,SLC8A1,SLC20A2,ABTB1,CDK5RAP2,MBD5,SNRPN,UNC80,KDM4B,ZCCHC24,KIF21B,ZSWIM8,NMNAT2,EMC1,SPTAN1,TSPYL2,NFASC,LHPP,CLSTN2,ITPRID2,ERBIN,NCDN,ZSCAN29,SEPT8,DIP2A,KANK1,AJAP1,PRRC2C,ZFR2,SYNE2,RHBDL3,SYN2,SYPL1,TACR1,KAZN,ROBO3,PDLIM2,ADGRL3,NAT16,TNS2,AHCYL2,PMS2CL,TGFBR3,RELL2,FAM124A,CABIN1,NPL,METTL3,ZMYND8,FNDC5,LINC00689,NSD2,ZNF711,ATP6V0E2,ZNF213,DHX33,MAP3K12,EMSY,SLC17A7,PCBP4,LAS1L,PRRT4" MicroRNA hsa-miR-3174:mirSVR_highEffct hsa-miR-3174:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.70E-89 2.08E-85 1.94E-88 1.79E-87 231 969 "KCNH8,KLHL32,GALNT13,ADD1,ERMN,PLEKHH1,PWWP2A,KIDINS220,CC2D2A,HFM1,C1QTNF3,SMIM17,ALCAM,CEP126,FAM135A,ALK,AMT,OGT,PARG,APC,LGR5,TMEM263,ASPH,ATP2A2,N4BP2L1,ADGRB2,ADGRB3,DST,IL33,CA8,PTBP2,CBR1,MTMR7,C1orf52,CDH2,LRRFIP1,CCPG1,DIS3L,RCBTB2,CHGB,CASC2,SYNPR,B4GALT6,CNOT8,QKI,AKAP5,ABI3BP,BAG4,SEC31B,CREM,GDA,FEZ2,LRRC3B,PDE4DIP,CST3,UBXN2A,KATNAL2,KIAA0586,DGKB,BRINP1,SACS,RABGAP1L,FAM107B,CHRDL1,GRIN3A,ABCC5,ABCC9,EDNRA,HIPK3,SUGP2,EGFR,GOLGA7,PAN3,EPB41L1,EPB41L2,EPHB1,RTN3,TAOK3,FGF1,SUCO,ANKFY1,NBEA,PDLIM5,GABRA1,GABRG2,DISC1,GART,LRRC37A6P,MYOZ2,GLRB,KDM2B,ADGRA3,LILRA1,CNTRL,GRIA1,GRM1,FAM19A2,KAT7,PSIP1,MAEL,PADI2,ATXN2L,HMGB1,HNMT,DHX35,SHISA6,IDH3A,USP54,JAK2,SLC35G1,KCNJ10,KLC1,IPO5,NCOA7,MARK1,MATN2,TM6SF1,KCTD6,KITLG,MID1,PPM1L,MITF,ERICH3,NASP,NDUFA5,NELL2,NF1,SLC11A2,NRGN,IGSF11,PCSK5,PDE4B,ENPP2,PDPK1,BEST3,ZFYVE21,PCDH18,PMP22,TRHDE,ING3,MINDY2,KANSL1,GRAMD1C,DIRAS2,PRPSAP2,WBP1L,PSMD13,CNTLN,BDNF-AS,PTHLH,PTPRB,ZSCAN2,SUSD4,MSANTD2,ZYG11B,FIGN,RFX4,RNASEL,TMLHE,KLHDC8A,TMEM206,LRRK2,ATAT1,COPZ1,MAGI3,SLITRK3,DZIP1,SLC1A6,YPEL4,SEPHS1,ZNF415,SNRPN,TMCC1,ENKUR,KDM4C,ZC3H13,MCF2L2,CLASP2,TROVE2,NKAIN2,ERBIN,NXT2,STAU1,SEPT8,TTBK2,FNDC9,TBCEL,TPCN2,RPGRIP1L,GPRIN3,TEX15,SIK3,SIRT1,AP4E1,SLC44A1,THRA,TMEM9,TMPO,ZNF384,SYNPO2,RUSC1,KCNE5,CLHC1,FAM155A,UGT8,FLRT2,P2RY12,NSD2,PCDH20,ZIC3,ZNF540,MKRN3,LYPD6,ZNF184,ANKS1B,SH3GLB2,SMARCAD1,SYNC,CA10,EMSY,DNALI1,PCDH15,EPM2A,ST7,KAT6A,HNRNPA3,PHTF2,CASC15,NETO2,FAM198A,JPH3" MicroRNA hsa-miR-670:mirSVR_highEffct hsa-miR-670:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.42E-89 2.48E-85 2.32E-88 2.14E-87 232 978 "CLK4,ADCY2,ADD1,PTCHD1,BEND6,AP2A2,CEP126,CARNS1,CNIH2,PKP4,APC,BCAS1,SHTN1,ASPH,DDX3Y,ATP2B3,TTLL9,SEC11C,CFLAR,ARHGEF7,SCAPER,GYG2,CACNA1E,CACNB2,CALB2,CAMK2D,ARHGEF2,ZBED1,CHM,CHN2,JAM2,NDST3,KIAA1549L,C4orf33,QKI,LY86,ARMC8,SUMF2,CNRIP1,CP,C2CD2,CREM,NCOR1,GDA,PHACTR3,CFAP61,ST18,CCDC144A,TOX,ZFYVE16,ZNF337,DGKB,NTM,TMCC2,NR1D2,RCAN1,GNE,ARRDC4,ABCC5,EBF1,EDN1,FAM135B,FCF1,PHF20L1,TMEM132E,PLEKHA1,MRNIP,EPHB1,CDKL3,CLVS1,SCML2,CORO2B,FCGR1A,FER,FGF14,SEMA4D,TACC2,STAU2,NRG3,PHYHIPL,CHL1,ACSS1,KIAA1841,SULT1C4,GPR162,RAB30,GLS,ZNF638,GNAL,GNAS,GNG4,WDFY3-AS2,GOLGB1,GPD2,FUT10,GPR12,LPAR4,CECR2,GRB10,GRIA4,GRID1,BTN2A1,ZBTB49,FAM107A,ZHX1,AGBL5,HNF4G,HNMT,NEGR1,SCRT2,NME9,KCNJ9,KCNK2,KCNN2,KIF5C,LIMS1,MARK1,MBD1,MDM4,MEF2C,ZNF680,ZNF92,MTR,MYT1,NCAM1,NCAM2,NDUFA5,NF1,DNHD1,HCN1,OPA1,PIK3C2A,PKM,HMGCLL1,EXOSC10,SEPT4,DRAM2,PPP3CB,GRAMD1C,PROX1,BCAS3,CNTLN,TMEM260,STK32A,ZIK1,PTPRE,CEP97,RALGDS,FAT4,ZNF493,RFX5,UBR7,SEC61A2,TMLHE,CARF,GSTCD,ADAL,ABCA11P,AMER2,MIR124-2HG,SEMA6D,ATXN7,SCN3A,LINC00461,SLC30A10,ASRGL1,COPZ1,FRMPD1,MAGI3,ZNF365,PPP4R3A,LRRC55,SLC9A5,SLC22A4,RCOR3,ANKRD36,SNCA,CMTR2,SNRPN,UNC80,TNIK,KDM4C,KIF1B,CDK19,ZC4H2,SS18,ZSCAN29,ELOVL4,SEPT8,ARHGEF9,PLCB1,TBCEL,ZFP90,RPGRIP1L,SYNE1,RALYL,SLC44A1,TLR4,NR2E1,C5orf64,PIK3R5,NPL,TPM4,RGMB,PRMT8,ZKSCAN5,FAM155A,SLC13A3,ZFP37,ZIC1,ZNF708,ZNF19,ZNF24,TRIM9,ZNF177,FSTL5,SPIRE1,MAP3K12,EMSY,PRDM2,XKR7,PCDH15,ST7,MARCH8,UBE3B,HNRNPA3,ZNF248,RNF170,SSPN,IFT88,SLC4A10,FAM198A" MicroRNA hsa-miR-192*:mirSVR_highEffct hsa-miR-192*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-88 6.22E-85 5.81E-88 5.35E-87 224 917 "ACADM,NDRG3,ADAR,KLHL32,ADD2,BRAP,ZNF608,CC2D2A,BBOX1,GPRASP2,PKP4,SHTN1,AQP4,TMEM263,RASL11B,ATP6V1G2,MIR9-3HG,SYNJ1,SGCE,MMD2,SLC25A14,MAP7,AIFM1,LRBA,SEPT7,CDC27,CDH2,LARGE1,TIGD7,RCBTB2,CHN2,PLEKHB1,TAOK2,AKAP6,CNRIP1,CLOCK,RBM39,OSBPL3,VCAN,PDE4DIP,DZIP3,NRSN1,DCAF4,HDAC9,ARHGAP32,TOX,MATR3,TMEM170A,DAPK1,DDX46,DMD,DNM1,ECM2,E2F6,EDN3,FRY,OPTN,YAF2,AASS,EPHA5,RABEPK,F3,CLVS1,PTK2B,SCML2,CEP78,GORAB,FER,SUCO,SYNCRIP,NBEA,NPTN,DACH2,STAU2,OGA,FYB1,STAG2,GALNT15,GABRG2,TRAF3IP2,CAB39,ERAP1,MTHFD2,ZNF559,ATP8A2,MYOZ2,NEU3,MMADHC,MALT1,CBX1,GNAS,GNG4,GPD2,STMN2,GRIA4,NR3C1,KAT7,GSTT2,DDX19B,MIER3,VSIG4,HMGB1,HNRNPK,HSD17B1,SMAP1,C5orf24,SCIN,OLFM3,TTYH2,LAMP2,MAP4,LRP1B,MOBP,CD200,ZNF92,RSPO2,NAP1L1,NDUFA5,NEFM,NF1,OTOGL,NFE2L2,TREM2,BEST3,ZNF655,ST8SIA5,SEPT4,KANSL1,PKN2,PRKCZ,EPDR1,GDPD1,CNNM2,SNRK,CNTLN,PTHLH,TMEM260,PTPN13,ZNF615,ZNF493,MORC4,GTDC1,UBR7,RIC8B,CARF,STK32B,NCBP3,CCDC112,TRAPPC13,ATXN7,LRFN5,SCP2,ITSN1,NLGN1,NUBPL,ZNF365,FAM81A,FAM214B,ZNF430,SLC6A11,NAPB,ATF7IP,TET1,SORCS3,SMARCE1,RCOR3,ANKRD36,SON,PDZD2,ZSWIM8,MYCBP2,ZNF423,KIF1B,SPART,TROVE2,ITPRID2,NKAIN2,NXT2,ADHFE1,KANK1,FGD4,VAMP1,SYT1,CAMTA1,TCEA1,EHBP1,SATB2,RPGRIP1L,SYNE1,TEX15,KHDC1,THBS4,SLC44A1,BHLHB9,NPL,ANKRD20A2,CLHC1,UBE3A,CCDC14,TBC1D15,WIPF1,NSD2,GUSBP1,ETNPPL,ZNF708,GPR158-AS1,ZNF138,ZBTB38,SPIRE1,UPF3A,ADAMTS9,NAV3,KCNAB1,EPM2A,MRPL47,PAK5,PHTF2,FBXO36,CASC15,MSRB3,DPF3,RNF146,SLC4A10,ZNF30" MicroRNA hsa-miR-448:TargetScan hsa-miR-448 TargetScan 1.38E-88 7.74E-85 7.22E-88 6.65E-87 168 509 "ABAT,C3orf14,ADD1,HECW2,KCTD16,DOC2A,ANK1,ANK3,CNTNAP1,APBB2,APC,ARNTL,PCDHGB4,ATP2B2,DCAF5,BSN,LDLRAD4,CACNA1D,CABP7,CCNT1,INA,CDH10,DCLK1,CFL2,NMT2,IGLON5,ARHGEF6,IQCK,ARMC8,BAG4,HAPLN1,CCDC144A,LIN54,BRINP1,DCC,PLEKHM1,MYEF2,KLHL3,DMD,CALN1,CPEB2,DTNA,EBF1,RASGRP1,KLHL5,EFNA3,MBNL2,RGS17,KCNMB2,GPHN,ETV1,SCML2,FOXO3,NBEA,ATP2C1,DOT1L,NRG3,GAB1,GABRA4,GABRB3,FAXC,KDM2B,FERMT2,GPR37,RAPGEF4,RFFL,GRIK2,GRIK3,GRIK4,ADAMTS8,GUCY1A2,FRMD5,BACH2,HNRNPK,SCRT2,JAK1,KCNA4,KCNA6,KCNB1,KCND1,KCNK3,KCNQ3,KIF2A,KPNA5,LIMS1,PAXBP1,HECTD2,MEF2C,MITF,JAKMIP3,MYH3,MYO5A,NCAM2,NEUROD2,NFIA,NFYA,HCN1,KCNK10,PCDHGC3,PCDH8,PDE4D,PIK3R1,CCSER2,MTRF1L,FAT3,PRKAB2,PROX1,PTPRE,RAB5B,CEP97,RAD51D,OXR1,RASGRF2,ERI2,GTDC1,KIF7,RAVER2,ROBO2,RORB,RIMKLA,SATB1,SCN4B,FAM102A,NLGN1,ABLIM3,PKNOX2,ARHGEF40,BTBD7,NMNAT2,HECW1,CDK19,RBM26,NPAS3,NFASC,C11orf87,FAM168A,ATP11A,ACSL6,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,PSD3,CRTC1,CBX5,HEY2,FAM124A,AMOT,FLRT2,RICTOR,KCNK12,CADM2,RGS7BP,FZD3,PIANP,FXR1,GAN,JPH3" MicroRNA hsa-miR-449c*:mirSVR_lowEffct hsa-miR-449c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.76E-88 9.86E-85 9.19E-88 8.46E-87 224 919 "ACADM,CLK4,TMCC3,SORCS1,PLEKHH1,OSBPL1A,AK2,LRRC7,CARNS1,ANK3,ALS2,PPFIA3,TMEM263,IGDCC4,SPTBN4,ZFYVE28,PDE8B,CAPRIN2,BRINP2,ATP1A2,ALDH7A1,MTMR9,CADM3,DPY19L3,SNAI3-AS1,BCHE,SYNJ1,CA8,CALB1,CAMK2D,CANX,MAP7,SHISA7,MYOM2,CLGN,SOCS6,CHM,CLCN4,TPP1,CLTC,ANKRD35,SUMF2,NRG2,CHD1L,GDA,CLIP3,OSBPL3,CSNK1G3,CNTNAP2,KIAA0040,RIMS2,RUBCN,CCDC144A,KIAA0408,HDAC9,ARHGAP32,KATNAL2,RIPOR2,FRMPD4,ZNF337,BRINP1,GIT2,KIAA0319,KLHL3,CCDC3,CDON,DTNB,SNX29,FAM135B,FAM13A,ABI2,EGR3,RASA4,EML1,PAN3,ENPP6,NCALD,CDHR1,MRPL37,MRVI1,ZIC4,TAOK3,SUCO,SEC23B,SYNCRIP,FOXM1,PDLIM5,NSG2,DACH2,NSG1,GABRB1,ARPP21,KIAA1841,GCNT2,CYP46A1,MSL3,GLUL,ADGRA3,GPR34,TMEM121B,FRMD5,ARHGAP19,HLF,GABARAPL2,DHX35,LRRC75A,IFI16,DOCK7,IL6ST,JAK1,KIF5C,LAMP2,GPR155,MAT2A,MATN2,SRSF12,KCTD6,SCAMP5,MITF,AFF1,MTTP,NCAM1,NCF2,NEK1,HCN1,TBC1D25,CNTN3,PFKFB2,PIK3C2A,HMGCLL1,PRIMPOL,RC3H2,LRP12,PPARA,PPP3CB,DEF8,NCR3LG1,ZSCAN32,PTPRG,PTX3,RIPOR1,TUG1,TMEM231,FAM66C,ZNF793,FAT4,RAP1GAP,RAP1GDS1,SLC6A15,TRIM68,RNASEL,ALG9,RAVER2,ROBO2,MRAP2,TMEM100,BAALC,ZNF671,ADAL,CLIP1,FOXRED2,DRAXIN,ATXN2,SCN2A,SCP2,KIF27,ZFP30,FERMT1,CTXN2,ZNF365,SLC6A1,SLC9A5,SLC14A1,SLC15A2,EFHD1,GKAP1,USP33,DOP1A,ITPRID2,INKA2,SEPT8,DIP2A,SULF2,FGD4,PRRC2C,NUDT10,PLCB1,SYT1,ATP11A,TACR1,EXOC7,PDLIM2,UNC5D,TBCEL,ACSL6,TCF12,OBSL1,USP32P1,DICER1,CRB1,GZF1,NPL,C9orf85,SYNPO2,TRIO,PPIL6,ANKRD20A2,PITPNB,FLRT2,GPR158-AS1,CELF4,DPYSL5,CADM2,EVI5,ADAMTS9,GAL3ST3,URM1,EPM2A,DOCK8,KAT6A,PHTF2,ADAMTSL3,JMJD1C,ZNF248" MicroRNA hsa-miR-1206:mirSVR_highEffct hsa-miR-1206:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.27E-88 1.27E-84 1.19E-87 1.09E-86 237 1027 "FMNL2,KLHL32,GALNT16,DSCAML1,ADD3,PWWP2A,NME5,TAOK1,LRRC7,SEMA6A,ALCAM,BBOX1,PPFIA1,APC,TNRC6C,SHTN1,TMEFF1,ARNTL,NCOA1,SLC4A4,ATP2A2,TTLL9,CFLAR,DST,WASF1,CACNA1E,CACNB2,CABP7,SLC25A14,CBR1,KRIT1,CCNH,USP6,DGKI,KCNAB3,CDH10,ABI3BP,RCHY1,HAPLN1,CSNK1G3,SOCS5,PHACTR3,SLITRK5,CFAP61,PUM1,ST18,CX3CR1,DOCK4,GPRASP1,FRMPD4,KIAA0586,DGKB,AIF1L,ZEB2,ZBTB24,HP1BP3,NTM,RAB39B,CPEB2,DRD1,PDCD6IP,E2F5,PHC2,FCF1,FRY,PHF20L1,PLEKHA1,USPL1,TUBD1,EPB41,EPB41L2,SIRPB1,CLVS1,ABCA8,TMEM132C,SEC24B,OLFM1,PRKAG2,CAP2,ATP13A4,C2orf88,POMT1,UFM1,PDLIM5,TPK1,CAMKK2,ZNF605,NSG2,ST6GALNAC3,NSG1,ADGRA1,CHL1,DISC1,WASF3,GATM,SULT1C4,ARFIP1,HEPN1,PPARGC1A,GK,HTATSF1,POLL,FUT10,STON1,CNTRL,RAPGEF1,GRIA2,DIDO1,GRM7,FAM19A2,MFSD2A,IRAK3,RASSF8,AGBL5,HNF4G,HNMT,ZDHHC15,TCEAL6,HSF2,IDH3A,IDH3B,C5orf24,LIX1,BRINP3,JAK2,KCND2,KIF5A,VWA5A,LRP1B,KITLG,MITF,WDR49,MT3,PABPC1L2A,NOVA1,LRIT2,NTRK2,NUMA1,GPR137C,PCDH9,PDCD2,SLC10A4,ZDHHC8,GDAP1L1,NALCN,PIK3C2A,ANLN,FAM216A,EPB41L4B,SH3KBP1,POLR2F,LRRN3,PPP2R5E,PPP3CA,PPP3CB,PKN2,PRKCZ,GRAMD1C,MDGA2,CNTLN,ANKHD1,PTPN13,RASGRF2,BSDC1,GTDC1,FIGN,KLHL11,SEC61A2,GSTCD,YY1AP1,TCP11L1,ABCA11P,ZNF568,AP1AR,ATXN2,ATXN7,SCN3A,SCP2,PEAR1,CHD9,BTBD3,NAPB,ATF7IP,CPEB4,ZNF667,SMARCE1,KIF21B,UHRF1BP1L,CDK19,CLASP2,ZNF302,STAU1,SEPT8,DIP2A,VPS13A,PLCB1,COBL,C12orf76,ANKRD12,MTCL1,CAMSAP2,ADGRL3,TBCEL,ATMIN,SYNE1,SLC19A3,USP32P1,ARHGAP9,FRYL,ZFPM2,SPX,ZMAT3,MTMR14,TLL2,C5orf64,C9orf85,STXBP4,ZMYND8,PPIL6,TSC1,ZKSCAN5,CADM1,FAM155A,VLDLR,TBC1D15,SLC13A3,KCNT2,GPR158-AS1,ZBTB38,FSTL5,FIP1L1,FAM47E,EPM2A,AMN1,FRMD6,ZNF30,FAM198A" MicroRNA hsa-miR-3171:mirSVR_highEffct hsa-miR-3171:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-88 1.69E-84 1.57E-87 1.45E-86 254 1174 "RALGAPA1,NBAT1,CSMD3,FMNL2,AXIN2,HECW2,PCDH19,OSBPL8,SPOP,CEP126,BCAR3,PCDH10,FAM135A,ZFAT,PHF12,PKP4,APC,ASPH,ZSCAN18,ATP2B1,DPY19L3,TTLL9,DCAF5,BID,DST,IL33,CACNB2,CALB1,KALRN,ZNF501,ENTPD6,CDC27,L3MBTL4,CFL2,FOXN3,CHN2,SYNPR,NDST3,PPT2,NRXN1,NIPBL,MYRIP,CP,ARHGEF10,VCAN,PDE4DIP,CTNND2,RIPOR2,KIF26A,MATR3,ZEB2,HP1BP3,DDX46,ALKBH8,PLPPR4,SACS,G3BP2,DLG3,NR1D2,ACOT8,DTNA,ECM2,DNAJB6,DNM1L,AASDH,SNX29,KLHL5,OPTN,PHF20L1,APH1A,EIF4G2,RGS17,PCOLCE2,EML1,ENO2,ETV1,F8,ARMCX1,FAM198B,DLC1,MED12L,POLR1B,POLK,CAP2,PCYOX1,FLT1,PSD2,NELFCD,WDR83,ZNF605,ST6GALNAC3,STAU2,MSANTD4,AP4B1,MPP6,OGA,PHYHIPL,STAG2,MEGF11,HRASLS5,GABRA3,GABRA5,GABRB1,ARPP21,SALL3,SYT17,KIAA1841,GATM,MSTN,RND1,GLRB,PCDH11X,GNAS,ZNF782,NUDT21,GRK4,RAPGEF4,GRIA2,PLCD4,FAM19A2,BVES,AP4S1,ADAMTS6,FAM222A,HAS2,MIER3,SCRG1,MSL1,ITIH2,JAK2,KCNA4,KIF5C,STXBP5,LAMP2,VWA5A,HECTD2,NCOA7,SYT9,SHC3,MEIS1,POC1B,MMP16,ERICH3,ADAM22,MSR1,RSPO2,MYCN,MYO6,NAP1L3,NDUFA5,NFE2L2,VWA2,PBX1,PDE3B,PDGFRA,FAM98B,A2ML1,HMGCLL1,PRRX1,ING3,CRLS1,RANBP3L,EPDR1,BCAS3,DEF8,PTHLH,TMEM260,PPP2R3C,SLC25A48,USP47,SUSD4,RBBP6,VEPH1,SLC6A15,TRIM68,ERI2,MORC4,RFX2,CARF,ROBO1,EPHA10,ACER3,PTGR2,WLS,ZNF331,AP1AR,DGLUCY,ATXN2,SCN3A,LINC00461,SCP2,HES6,NLGN4Y,ITSN1,HKDC1,MAGI3,FBXO11,ST3GAL3,ANKRD6,PREX2,SLC2A5,SLC9A5,SLIT1,SMARCD3,SMARCE1,ANKRD36,LIMCH1,RIMS1,UNC80,SOX2,SOX5,KIF21B,BDP1,TEX2,LMO3,ATP10B,TTBK2,STXBP1,TACR1,ZFP90,WASHC4,SYNE1,DOCK9,RALYL,PCDHA2,FRYL,AP4E1,SLC44A1,MTMR14,TIMP4,NR2E1,TMPO,DAAM2,C9orf85,RUNDC3B,MTCH1,LGI4,ZIC1,MICU3,ZNF28,TRIM9,MKRN3,LYPD6,ZNF184,SMARCAD1,SYNC,UPF3A,LRP8,LINC02210,STOX2,ADAMTS9,KAT6A,NLRP3,SLC4A10" MicroRNA hsa-miR-129*:mirSVR_lowEffct hsa-miR-129*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.62E-88 2.03E-84 1.89E-87 1.74E-86 245 1097 "SDE2,ADCY2,ADD2,PWWP2A,ESYT2,ZNF578,ADGRF5,C1QTNF3,SYT13,ANK3,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,SHTN1,AQP4,PDXK,CDK13,MARK4,NCOA1,RASL11B,NOL4,TTLL9,BCL2L2,DCAF5,CFLAR,KSR1,SCAPER,MYRF,LDLRAD4,CACNB2,KALRN,SHISA7,CLDN10,CCKBR,LARGE1,RCBTB2,SRSF11,CHN2,RAB28,PLAA,DNAJB5,MAP4K4,NIPBL,ARHGEF6,AKAP6,AKAP5,RCHY1,FAM171B,SH2B1,AKAP12,SEC24C,FEZ1,OSBPL3,CFAP61,DCAF4,RUBCN,HDAC9,RIMS3,SPOCK2,IP6K1,AIF1L,ARMCX4,ZEB2,MYEF2,TIAM2,RUSC2,ALKBH8,DLG2,DNM1,HS3ST2,GNE,ECM2,ABCC9,PHC2,TMTC1,FRY,SIDT2,GPR61,EBI3,VPS13B,EPHA5,MRPL37,TOMM40L,GORAB,OLFM1,FGF13,SUCO,MEX3B,PCYOX1,C2orf88,TPK1,ARFGAP2,CAMKK2,ATP2C1,ERGIC3,CELF1,MSANTD4,TVP23A,GABRG1,AHCYL1,BRPF3,B4GALNT1,NEK6,ATP8A2,LRRC37A6P,KDM2B,GPD1,GPM6B,GRIA4,CACFD1,GRIN2C,NR3C1,CLASRP,RNF165,TMEM179,TOX2,HMGCL,SHISA6,MSL1,TJAP1,IL12A,ITPKA,GPR62,STXBP5,CYP27C1,TTYH2,SYTL4,MAP4,SYT9,AFF1,XRRA1,ADAM22,MSR1,MTR,ZNF862,SFR1,NEK1,NOS1,CNOT4,NTRK2,NUMA1,TBC1D25,PDCD2,PRTG,PDE3B,NALCN,SEMA5B,PLXNB1,EXOSC10,POLG,MED1,PPP2R5E,PPP3CB,RASGEF1B,PRKCB,MAPK3,PSD,QRICH1,ELOVL2,PTPRG,PTPRO,PEX5,RAP1GDS1,BSDC1,TRIM68,GTDC1,RFX4,UBR7,RLBP1,ZNF532,GSTCD,ROBO1,SNX22,ATAT1,ZNF568,STX1B,FAM192A,SEC14L1,KIF21A,FBXO11,R3HDM2,CNKSR2,PAAF1,ZNF365,EPN2,SLC6A8,SLC14A1,BTBD7,SPHKAP,SLN,CXXC4,SNRPN,SCN3B,WDTC1,SOX2,SOX5,SOX10,NMNAT2,STAU1,CEP68,PHLDB1,SEPT3,NSFL1C,ACSBG1,VAMP1,VPS13A,TMEM150C,SYT1,COBL,KLHL4,TCF7L2,CLASP1,SYNE1,USP32P1,CYB561A3,LEFTY2,AP4E1,TGFBR3,MTMR14,TMPO,RGMB,ELP5,NEIL2,AMACR,FNDC5,CADM1,UBE3A,RICTOR,SF1,SLC26A10,ZBTB38,AMZ1,MEIS3,DNALI1,STOX2,HPS4,GAL3ST3,NAV3,C12orf4,HNRNPA3,FBXO36,CAMK1G,NUP214,VANGL2" MicroRNA hsa-miR-612:mirSVR_highEffct hsa-miR-612:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.75E-88 2.11E-84 1.96E-87 1.80E-86 233 996 "ADCY6,SLC12A5,SORCS1,ADORA2A,FAHD2CP,KIDINS220,NLGN4X,SLC44A5,SNX32,FAM135A,SUGT1P4-STRA6LP-CCDC180,ALS2,VAT1L,ARNTL,STK33,CCDC74A,CAPRIN2,CCAR2,ATP2B2,CFLAR,CACNB2,PTBP2,CAST,CBS,CLDN10,METTL6,INA,P2RX6,CD86,CD38,ZMYM4,MAGI1,TIGD7,GPR37L1,RAB28,CLU,MAP4K4,COL4A5,CHD1L,GDA,TRIM69,CSNK1G3,ATRNL1,SOCS5,VAC14-AS1,DZIP3,PPP1R16B,CTH,CFAP61,RUBCN,ECE2,CCDC144A,TCAF1,ARHGAP24,ARMCX4,HEPH,MAGI2,ZC3H11A,DDX46,SV2B,CPEB2,DPYSL2,SNX29,SGK2,KLHL5,EFNB3,FAM13A,ABI2,EGR3,CERCAM,DMTN,ANKRD13B,SRRM1,ZNF549,FAM198B,ATP8A1,STRADA,KAT8,SLC9B2,FGF1,SPSB4,BAIAP2,CAP2,NOP56,TMEM175,TRIM16,ARFGAP2,STAU2,MSANTD4,AP4B1,GABRA1,GABRA3,GABRA5,BRPF3,B4GALNT1,ZNF274,MYOZ2,NEU3,GCNT2,GFAP,COPS8,SPIN1,KDM2B,MAP7D2,POLL,GRIN2D,GSTM5,GYG1,MIER3,VSIG4,IL6ST,LRRTM3,KCNB1,GPR62,KCNK2,KCNMA1,KHK,KIF5A,PAXBP1,NCOA7,LSS,PIK3AP1,MBNL1,ADAM11,MEF2C,MEIS1,KCTD6,MMP16,MOG,CTNNA3,MYBPC1,MYO7A,NAP1L2,NEFH,NEK1,NFE2L2,VWA2,NTRK2,NTRK3,IGSF11,OCRL,OGG1,OPHN1,CLDN11,TREM2,PAK3,GDAP1L1,PKM,PURG,SEPT4,FAT3,POLG,NXPH1,SH3KBP1,MED1,PPP1R1A,TATDN3,PCDHB17P,PPP2R2B,PPP3CB,ZSCAN32,EML5,PPP2R3C,MARCH1,RAD52,ARID4A,RET,RGS4,RGS12,ROBO1,ELP2,MRAP2,ATAT1,RTKN,CLIP1,ZNF568,RMI1,DGLUCY,SALL1,ATXN7,TNFRSF19,SEC14L1,TRA2B,ITSN1,NTNG1,HKDC1,CHD9,R3HDM2,CCDC92,ANKRD6,ATF7IP,SPHKAP,SNCB,SNCA,CMTR2,SNRPN,PDZD2,TNIK,SPTAN1,LMO3,SS18,ZSCAN29,NSFL1C,FAM168A,COBL,MCF2L,TMEM136,SATB2,TCF12,ARHGAP9,PMS2CL,ITGB3BP,DAAM2,PRMT8,TRPC1,RFTN2,WIPF1,P2RY12,SF1,ZBTB14,MICU3,TRIM9,GPR158-AS1,NDRG4,REEP1,SMARCAD1,EMSY,LMAN2L,TRIM16L,C12orf4,UBE3B,HNRNPA3,FRMD6" MicroRNA hsa-miR-183-5p.2:TargetScan hsa-miR-183-5p.2 TargetScan 3.89E-88 2.19E-84 2.03E-87 1.87E-86 176 565 "ABAT,KLHL32,ADCY6,PTCHD1,KCTD16,OSBPL8,LRRC7,ALK,OGT,LRCH2,PKP4,GPAM,CDK13,PDE8B,BRINP2,B3GALT2,DPY19L3,ADAM23,MTMR3,JAZF1,NIPA1,CDK5R2,LDLRAD4,CACNA1E,CACNB4,CAMK2D,LDB2,DGKI,REPS2,CDC27,EVI5L,L3MBTL4,DLGAP2,CACNA2D2,RAB3C,MAP4K4,NIPBL,MYRIP,CDC42BPB,PREPL,LRIG1,CHD5,RIMS4,CNTNAP2,PPP1R16B,ERC2,APPL1,CTNND1,ARHGAP24,FRMPD4,RASSF2,IST1,SACS,RABGAP1L,DLG2,HS3ST4,CALN1,GNE,E2F5,FEM1B,PHF20L1,ABI2,EIF5,GPHN,FHL1,PCYOX1,FAM49B,ATP2C1,FYN,GAD2,BRPF3,B4GALNT1,GAP43,GFRA1,PCDH17,RAB30,AIFM3,KDM2B,GPM6A,GPM6B,GPR12,PCLO,RAPGEF4,GRIA1,PARD3B,GRID1,GRM5,GRM7,KAT7,RASSF8,FRMD5,BACH2,HMGB1,CDH20,KCNC2,CLVS2,KCNN3,LAMP2,HECTD2,LSAMP,NAT8L,MAP2,MBNL1,CHIC1,MEF2C,MID1,PPM1L,MITF,NEUROD2,NOVA1,NOVA2,NPTX2,IGSF11,OGDH,P2RY1,KCNK10,PAK3,PIK3C2A,PIK3R1,FAM216A,PLTP,PRRX1,EPB41L4B,POU3F2,MED1,CNNM2,APTX,PTPRD,RALGDS,ATG16L1,BSDC1,RFX3,PRIMA1,CYB561D1,ROBO1,MCMBP,RIMKLA,SATB1,ATXN1,MRAS,PPP1R9A,PPM1E,MAGI3,FNDC3A,BTBD3,ELMO2,CPEB4,ARHGAP26,NPAS3,RAP1GAP2,NFASC,LMO3,EPB41L3,LRRC4,DIP2A,AJAP1,KLHL7,COBL,ANKRD28,FBXW11,ARHGEF12,GPRIN3,AP4E1,CBX5,DDHD1,LRRC8A,RUNDC3B,RICTOR,PMEPA1,CADM2,NAV3,JMJD1C,IFT88,NETO2,GAN,PRRT4" MicroRNA hsa-miR-1285:mirSVR_highEffct hsa-miR-1285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.55E-88 2.55E-84 2.37E-87 2.18E-86 220 891 "SDE2,ADARB2,ADCY2,ADCY6,SORCS1,ADORA2A,KIDINS220,NLGN4X,SNX32,TAOK1,PCDH10,FAM135A,DPP10,SUGT1P4-STRA6LP-CCDC180,ALS2,VAT1L,STK33,CAPRIN2,CFLAR,CA4,KALRN,PTBP2,CBS,CLDN10,METTL6,INA,P2RX6,CD86,CD38,SEPT7,CDC25B,ZMYM4,LRRFIP1,TIGD7,GPR37L1,KIAA1549L,NRXN1,CLU,COL4A5,GDA,TRIM69,OSBPL3,CSNK1G3,SOCS5,VAC14-AS1,DZIP3,PPP1R16B,CTH,CFAP61,EDRF1,ECE2,CCDC144A,KATNAL2,ARHGAP24,PABPC5,HEPH,MAGI2,ZC3H11A,DDX46,SV2B,SGSM2,EXOG,DPYSL2,ABCC5,SNX29,RASGRP1,KLHL5,EFNB3,FAM13A,EGR3,CERCAM,DMTN,SRRM1,ZNF549,SRARP,FAM198B,ATP8A1,CEP78,KAT8,SLC9B2,FGF1,SPSB4,FGFR1,FLT1,NOP56,TRIM16,ARFGAP2,STAU2,GABRA1,GABRA3,GABRA5,BRPF3,ZMYND11,B4GALNT1,ZNF274,ATP8A2,GCNT2,SRCAP,GFAP,ZNF276,COPS8,KDM2B,MAP7D2,POLL,GPR19,GYG1,MIER3,ZIC5,IGSF1,IL6ST,LRRTM3,KCNB1,GPR62,KCNK2,KHK,KLC1,PAXBP1,NCOA7,PIK3AP1,MBNL1,MEF2C,MMP16,MOG,ZNF92,CTNNA3,MYBPC1,MYO7A,SFR1,NEFH,NFE2L2,VWA2,NTRK3,IGSF11,OPHN1,CLDN11,PAK3,PKM,PLCL1,SEPT4,FAT3,NXPH1,SH3KBP1,PPP1R1A,PPP2R2B,PPP3CB,GDPD2,ZSCAN32,EML5,PPP2R3C,MARCH1,OXR1,ARID4A,RET,RGS4,RIC8B,ROBO1,ELP2,ATAT1,RTKN,KCNIP2,ZNF568,RMI1,ATXN7,SCN8A,TNFRSF19,SEC14L1,COPZ1,ITSN1,SH3GL2,NTNG1,CHD9,R3HDM2,SLITRK3,ANKRD6,SEPHS1,ATF7IP,SPHKAP,SNCA,CMTR2,SNRPN,SPTAN1,LMO3,COLGALT2,SS18,SULF2,SEPT3,NSFL1C,JMJD6,DMXL2,SATB2,TCF12,GPRIN3,PMS2CL,ITGB3BP,ZMAT3,ERCC6L2,DAAM2,PRMT8,TRPC1,PPIL6,RFTN2,UBE2H,WIPF1,SF1,ZBTB14,ZNF711,MICU3,TRIM9,GPR158-AS1,NDRG4,REEP1,SMARCAD1,WNK1,EMSY,PRDM10,LMAN2L,C12orf4,KAT6A,FRMD6,SLC4A10" MicroRNA hsa-miR-548s:mirSVR_highEffct hsa-miR-548s:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.07E-88 2.85E-84 2.64E-87 2.43E-86 227 948 "CLK4,ADCY5,BRAP,ESYT2,CC2D2A,TAOK1,PCDH10,ALK,DPP10,MAP4K3,PHF12,CDK13,STK33,ASPH,DDX3Y,N4BP2L1,BACH1,ADGRB3,ZNF599,CFLAR,PROM1,DST,ARHGEF7,THSD7A,PTBP2,VXN,ISPD,AIFM1,CBFA2T2,CCPG1,SOCS6,CHM,CHN1,CASC2,MS4A7,QKI,SLC4A8,CHD1L,SEC31B,AKAP12,TRIM69,ABCG1,SEC24C,LRIG1,MICAL2,CSNK1G3,VCAN,FAM169A,UBXN2A,CTNND1,NRSN1,BOC,RIPOR2,ARHGAP24,DCAF8,TM9SF4,MATR3,SPOCK3,FAM107B,DLG2,DPH1,MAMLD1,ABCC9,E2F5,EDIL3,PHF20L1,ABI2,COQ7,SLC43A2,RTN3,NSRP1,RACK1,GORAB,KIAA1109,FGF1,POLR1B,FGF13,SUCO,FOXG1,JKAMP,SMC2,APOPT1,PHYHIPL,GABRB1,GALNT15,GALR1,DISC1,GATM,GHR,GK,TCERG1,GLI2,TNRC6A,GPM6A,NUDT21,ZNF496,CIT,GUCY1B1,MAP4K5,C1orf94,ZHX1,HLF,VSIG4,ACOT7,OPALIN,SMAP1,ZNF546,RBPJ,IGSF1,SCRT2,KCNC2,KCNN2,KCNN3,HECTD2,ARHGAP12,PIK3AP1,MAT2A,POC1B,MMP16,DBNL,CCDC80,MYO9A,RTL5,NUCB2,NUMA1,PAX6,PCSK5,PDCD2,PDE1A,PDE4D,PDGFRA,SLC10A4,GPR85,XRN1,FAM216A,PMP2,PMP22,TRHDE,EPB41L4B,MED1,PPP2R5E,KANSL1,MAPK9,BDNF-AS,TMEM260,STK32A,PTPRB,FAM120C,C1orf109,PTX3,ZNF615,CEP97,PLEKHB2,ATG16L1,DBX2,UBR7,KIF7,RIC8B,NUDT11,ROBO2,MRAP2,ZC3H14,CLIP1,SATB1,SCN2A,PRCD,TNFRSF19,SCG5,SH3GL2,FERMT1,NTNG1,MAGI3,FNDC3A,NLGN1,ANKRD6,NUBPL,ABLIM3,PPP4R3A,SLC20A2,ATF7IP,SORCS3,RCOR3,PALLD,UNC80,KDM4B,SCN3B,SOX5,SPATA7,SP4,ZNF423,ZC3H13,ERBIN,CEP68,DIP2A,PLCB1,SYT4,ATP11A,TCF7,ZEB1,PCDHB10,PCDHB3,USP32P1,FRYL,SIK3,FAM200B,DICER1-AS1,C18orf54,ACTR6,FAM124A,RIMBP2,ZNF346,SMUG1,AMACR,PPIL6,TSC1,UBE3A,DNAJC12,SLAIN1,ZIC1,ZIC3,ZNF24,ZSCAN26,CSDE1,PRDM8,KAT6A,JMJD1C,RNF146" MicroRNA hsa-miR-3128:mirSVR_highEffct hsa-miR-3128:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.16E-88 3.46E-84 3.20E-87 2.95E-86 240 1057 "NCKAP5,ACTN2,ARID1A,ADD3,SORCS1,KLHL13,HACE1,ALCAM,KIF6,DPP10,VAT1L,ZFYVE28,CAPRIN2,DACT3,ZBTB10,ATP1B3,DPY19L3,BCL2L2,DST,RAB29,BTRC,CACNA1E,CANX,CAST,KYAT1,CCKBR,USP6,RGN,ARHGEF1,CHM,PLAA,NRXN1,SRP14-AS1,COL4A5,ACBD5,TOGARAM2,CNRIP1,SLC35F1,PREPL,ARHGEF10,SIPA1L1,DZIP3,CTNND1,EDRF1,GPRASP1,IST1,ARMCX4,BLOC1S6,ZC3H11A,WDR20,ARNT2,NYAP1,DMTF1,DSCAM,ARRDC4,DNAJB6,DNM1L,ABCC9,SNX29,EDN3,EDNRB,HIPK3,FCF1,MBNL2,KCTD3,ELAVL2,PLEKHA1,ELAVL4,TMEM35A,SRRM1,ETV1,TESK2,GORAB,SLC9B2,MED12L,MEX3B,FOXF2,ATP13A4,FLT1,PDLIM5,STAMBP,STAU2,STAG2,GABRA2,CAB39,SIGLEC8,ALDH1L1,GGT7,TCERG1,GLS,RAPGEF4,GRIA2,GRIK2,RNF165,MAP4K5,RASSF8,UBE2QL1,NXPH3,FRMD5,VSIG4,TCEAL6,HSPA1L,MSL1,ZIC5,RBPJ,ZNF678,LRRTM3,ITPKB,KCNJ11,KCNMA1,KLC1,KTN1,TTYH2,C2orf80,MARK1,LYPLAL1,MAT2A,MDM4,MEIS2,MEST,TAGLN3,TCEAL5,PCDH9,PDE4D,PFKFB2,PFKFB3,SERPINE2,PLCL1,HMGCLL1,PMP2,RC3H2,EPB41L4B,MED1,PPP2R2B,PPP3CB,RASGEF1B,CEP41,MAPK10,GRAMD1C,PLPPR1,TMEM260,PTPRB,PTPRD,PTPRG,PTPRZ1,PEX5,ZSCAN2,TTC13,CEP97,PLEKHB2,FAT4,OXR1,RASGRF2,RADX,KHDRBS2,SLC6A15,ZYG11B,RFX3,SETD5,CARF,CCDC25,ELP2,PCMTD2,ATP8B4,ATAT1,SCN3A,SCP2,ITSN1,NTNG1,SLITRK3,NLGN1,SEC31A,PAAF1,ZNF365,SLC2A5,SLC6A11,RAB3GAP1,CCDC88A,SLC12A2,NAPB,ATF7IP,LIMCH1,CMTR2,UNC80,DOP1A,SON,CLUAP1,ZNF423,NPAS3,CLASP2,COLGALT2,ITPRID2,ELOVL4,SEPT3,NSFL1C,FAM168A,FGD4,ARHGEF9,VPS13A,FNDC9,PLCB1,SYT4,DDHD2,FBXW11,TCF4,SATB2,TPCN2,TRIM2,WASHC4,RALYL,USP32P1,ITGB3BP,GZF1,TIAM1,TK2,DAAM2,PRMT8,SMUG1,RUNDC3B,RPL7L1,PITPNB,PLEKHH2,VLDLR,WIPF1,LAT2,CLDND1,ZNF19,MICU3,DPYSL5,PRDM2,DNALI1,NAV3,WNK3,PLSCR4,FBXO36,CASC15,JMJD1C,MSRB3,SLC4A10,FAM198A" MicroRNA hsa-miR-218-1*:mirSVR_lowEffct hsa-miR-218-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.24E-87 6.96E-84 6.43E-87 5.92E-86 281 1426 "SYN3,SLC25A25,KLHL32,SLITRK1,BRAP,SNX30,SLC24A4,PCDH19,AGT,CC2D2A,HFM1,AMPD2,DPP10,MAP4K3,PHF12,DGKD,VAT1L,SHROOM2,RGS20,DNAH17,BRINP2,CHRD,ADAM23,RGS9,BCL2L2,DCAF5,SYNJ2,ARHGEF7,SCAPER,CASTOR3,LDLRAD4,CACNA1A,CACNA1B,CACNB4,TRIM41,CANX,VXN,CAST,HIP1R,MAP7,NFS1,USP6,CDK11B,CDC42,NUMBL,CHM,CHN2,CASC2,RAB28,NRXN3,CLTA,IQCK,FAM149A,CABP1,SLC35F1,ENTPD4,RBM39,GDA,CSF2RA,FEZ2,ARHGEF10,CSNK1E,VCAN,VAC14-AS1,UBXN2A,PNPLA8,CFAP61,SEC14L5,ECE2,MATR3,IST1,SCRN1,SIRPA,ARMCX2,DGCR5,GUCD1,FAM107B,ZNF582-AS1,EXOG,RAB39B,HS3ST2,CDON,DPYSL2,ABI1,DTNA,DNAJB6,DYRK1A,ABCC5,DNM1L,SYT15,EFNA3,APH1A,ABI2,KCTD3,SORBS3,MRNIP,TUBD1,NCALD,TUBB3,SCML2,ATP8A1,FCGRT,FKTN,STRADA,SLC9B2,FGF11,PCYOX1,SEMA4D,ERGIC3,STAU2,NRG3,OGA,STAG2,GAD1,HBS1L,AHCYL1,RAPGEF6,DISC1,CPLX2,KIAA1841,ADAM28,PPARGC1A,SPIN1,PCDH11X,PRUNE2,C1QL4,GRIA4,GRM8,LINC01089,BTN2A1,RNF165,SOX21,FRMD5,TNFAIP8L3,MIER3,OPALIN,NKD1,USP54,IL6ST,ITIH2,LSS,PIK3AP1,MARK1,LDLRAD3,MEIS2,SRSF12,XRRA1,RSPO2,HS6ST3,MYT1,TCEAL5,NME4,NUCB1,ODF2,CLDN11,P2RX7,SNTG1,PCSK1,PDYN,PIK3C2A,TMIE,PIK3R1,XRN1,PLIN1,PMP2,STRN3,LRP12,PRRX1,ING3,CRLS1,PRKACB,CEP41,PKN2,PRPH,DEF8,MDGA2,UHRF1BP1,SPDL1,TMEM260,FAM120C,TTC13,TUG1,USP47,PLEKHB2,RALGDS,ERI2,MRPS18A,RPRD1A,YY1AP1,RPL15,ZNF671,PAQR6,ABCA11P,HSD11B1L,ATAT1,ZNF354C,ATXN2,SLC30A10,ZFP30,ITSN1,FAM102A,KIF16B,FNDC3A,ST3GAL3,DZIP1,SLA,SLC4A3,PPP4R3A,PKNOX2,RAB3GAP1,BTBD7,ATF7IP,TET1,CPEB4,GKAP1,MYH15,RIMS1,KIF13A,SNRPN,PDZRN3,WDTC1,TRERF1,FNBP1,PEG10,BEX1,TSPYL2,ITPRID2,STAU1,PHLDB1,SYT11,TMEM150C,SYPL1,KAZN,UNC5D,CNTN2,TMEM136,TCF7L2,ZEB1,TPCN2,NAT16,DOCK9,USP32P1,HIF3A,CYB561A3,RNF216P1,FAM200B,TGFBR3,ZNF106,MTMR14,RELL2,ACTR6,R3HDM1,TPD52,TPM3,WBP2,METTL3,PRMT8,NTSR2,ZKSCAN5,SLAIN1,PITPNB,CLDND1,ZNF24,KCNT2,FMN2,LYPD6,ZNF154,FSTL5,SLC30A4,EVI5,ADAMTS9,WNK2,RGS7BP,DOCK8,UBE3B,KAT6A,PHTF2,RSPRY1,FRMD6,DPF3,LAS1L" MicroRNA hsa-miR-1257:mirSVR_highEffct hsa-miR-1257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-87 9.57E-84 8.84E-87 8.14E-86 233 1003 "ABAT,NBAT1,CSMD2,ARID1A,FMNL2,GALNT13,KIDINS220,AP2A2,HACE1,OSBPL1A,OSBPL6,ARHGAP20,LCORL,SUGT1P4-STRA6LP-CCDC180,PKP4,APLP1,API5,MIER1,SEMA4G,CADPS,LINC00173,ASCL1,STK33,ASPH,DACT3,NCOA1,ATP1B3,ATP2B3,BACH1,C5,CA8,CACNA1B,KALRN,CANX,SPAG9,CCKBR,METTL6,USP6,SEPT7,LGI1,TIGD7,CLGN,NDST3,NRXN1,QKI,ARHGEF6,AKAP7,FAM149A,BTF3L4,RCHY1,TBPL1,CPS1,CREM,RNF14,SNCAIP,FEZ2,MICAL2,NCAN,ERC2,CTNND2,NRSN1,ZSCAN23,ARHGAP32,FRMPD4,SPOCK2,DNAJC6,C8orf34,ZC3H11A,RHOBTB1,CHRDL1,NYAP1,USP3,DMTF1,PDCD6IP,DYRK1A,EDNRB,FSD1L,FAM13A,PAN3,TUBD1,LRRC17,KCNMB2,EXTL2,FAM198B,EFEMP1,IP6K2,SYNCRIP,EFCAB2,NBEA,ZCCHC17,SORBS1,ERGIC3,NRG3,ZNF512,NCKAP1,ERAP1,ZNF559,MSTN,SESN1,RND1,CRCP,MSL3,GNAL,ZNF782,PRUNE2,FUT10,NUDT21,GPR37,PLPP7,CIT,GYG1,FRMD3,KLF12,HMGCR,C9orf129,SMAP1,HTR5A,MSL1,IGFBP1,ZIC5,USP54,IGSF1,IL12A,INPP1,KCNJ5,KCNK2,IPO5,HECTD2,PIK3AP1,MAN2A2,LYPLAL1,MARK3,MEIS1,MXI1,MYO6,MYO9A,NCAM1,NCAM2,VWA2,NRCAM,NTRK2,PAK3,PCMT1,PDGFRA,ENPP2,PIK3C2A,PLXNB3,SPATA6,EPB41L4B,EPDR1,PLPPR1,PTHLH,PTPRO,SH3TC2,FAT4,MSANTD2,REV3L,PRRT2,RFX2,RGS7,RERGL,CARF,PNMA8A,TMEM100,NEK11,UEVLD,ZNF568,AP1AR,SAFB,SEMA6D,CSRNP3,ATXN2,SCN2A,FAM19A1,SUPT20H,SHC4,FNDC3A,NLGN1,SLA,SLC1A6,EPN2,CCDC88A,SHANK2,SPHKAP,RCOR3,UNC80,SON,PDZD2,FNBP1,MYCBP2,KIF1B,CDK19,NPAS3,LMO3,TAB2,CLASP2,TROVE2,ZSCAN29,SEPT8,ADHFE1,JMJD6,VPS13A,TMEM150C,FAM208A,ADGRL3,DMXL2,NSD1,FAM200B,CRB1,WBP2,RUNDC3B,TRO,CADM1,TBC1D15,WIPF1,CLDND1,XRCC4,ZNF17,ZNF28,KCNT2,TRIM9,ATP6V0E2,LYPD6,SPIRE1,PLPPR5,CA10,EMSY,WNK3,WNK2,PLSCR4,HNRNPA3,FBXO36,NETO2" MicroRNA hsa-miR-1275:mirSVR_highEffct hsa-miR-1275:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.33E-87 1.31E-83 1.21E-86 1.11E-85 218 882 "ABCF1,KCNH8,ACHE,ACLY,ABHD6,ARID1A,CSMD3,NDRG3,NDRG2,ADAR,DSCAML1,AXIN2,GRAMD1B,ADRB2,HECW2,CC2D2A,SPOP,LTBP4,FAM135A,ANK2,PHF12,GPAM,LGR5,ARNTL,LINC00173,PCDHGB4,NUMB,N4BP2L1,NOL4,BACH1,JAZF1,CACNA1D,LURAP1,SPAG9,CBLN1,INA,CBFA2T2,DCLK1,CACNA2D2,SYNPR,LHX2,EPS15L1,NRXN3,PPT2,TPP1,WHRN,SMARCAL1,CPS1,CRYBB1,CSF1R,CSF3R,FEZ1,ARHGEF10,OSBPL3,PLXNA4,CTNND2,ST18,CX3CR1,HDAC9,KATNAL2,TCAF1,DNAJC6,G3BP2,EXOG,CPEB2,DTNB,DUSP9,DYRK1A,EDN1,PHC2,EGFR,TNK2,COQ7,GPHN,ANKRD13B,CDKL3,PIPOX,STRADA,FDFT1,FGF1,FLYWCH1,NSG2,GABRA3,GAD2,JPH4,IP6K3,TUBA8,GGT7,RUNDC3A,HPGDS,TDRKH,CCDC184,EML4,GRIK2,SERP2,GRM3,GRM7,RNF165,UBE2QL1,NXPH2,ZDHHC15,LRRC75A,C5orf24,ZNF678,KCNJ10,KCNMA1,INSYN2,ADAM11,PTOV1,RSPO2,FXYD7,NOS1,NTRK3,NUMA1,IGSF11,OLR1,CLDN11,P2RX7,PCDHGC3,SERPINE2,PKM,PLP1,PURG,EPB41L4B,POLG,POU3F2,MAPK4,MAPK9,HYDIN,WBP1L,CNTLN,PTHLH,ELOVL2,PTPRO,PEX5,RAD51D,FAM66C,RALGDS,BSDC1,RDX,GTDC1,RFX4,SLC25A36,SETD5,SPIN3,ADAL,TCP11L1,ATAT1,KCNIP2,ITSN1,PPM1E,FBXO11,FHOD3,PPP4R3A,PKNOX2,SEPHS1,SIRT2,ELMO2,EFHD1,INAVA,TMCC1,FNBP1,MYCBP2,SPTAN1,TSPYL2,ATP10B,PBLD,TROVE2,LRRC4,NXT2,SEPT8,GANAB,VAMP1,VPS13A,ANKRD28,SYT4,TACR1,MTCL1,ROBO3,FBXW11,EHBP1,TCF4,TCF12,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SIK3,C18orf54,LEFTY2,TGFBR3,CDH22,MTMR14,SYNPO2,ZMYND8,MEAF6,BEST1,VSNL1,MICU3,ZNF32,SMARCAD1,CA10,CADM2,LRP8,GAL3ST3,PDSS2,ST7,TIGD6" MicroRNA hsa-miR-1225-5p:mirSVR_lowEffct hsa-miR-1225-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.01E-87 1.69E-83 1.56E-86 1.44E-85 231 989 "SYN3,NCKAP5,CSMD2,LRRC7,DOC2A,SEMA7A,MYH7B,SUGT1P4-STRA6LP-CCDC180,DGKD,BCAS1,API5,ASPH,PCDHGB4,CADM3,DPY19L3,ADAM15,ADGRB3,BCL2L2,CFLAR,JAZF1,CACNA1E,KALRN,CERS5,TMEM257,ENTPD2,LOC730101,LARGE1,CHGB,CHN2,PLEKHB1,ZFYVE9,CLTB,FAM149A,LETMD1,MYRIP,IGDCC3,CHD1L,SEC31B,CDC42BPB,AKAP12,UBXN2A,PHF14,CTH,GREB1,PUM1,CX3CR1,KATNAL2,DGKB,BRINP1,C8orf34,GSDME,NTM,RABGAP1L,SEC16A,GRIN3A,SLC29A4,CDON,FAM57B,DPP6,PDCD6IP,DTNA,DNAJB6,SYT15,CNNM1,YAF2,MBNL2,ELN,C8orf37,DCTN4,EPB41L2,EPHA5,STX2,DNAJC27,ZIC4,SCML2,CHST15,KAT8,PPP1R1B,ZNF589,FGF13,IQCG,FLT1,ANKFY1,EFCAB2,CELF1,NRG3,ZMAT1,GABRB3,ZMYND11,IP6K3,NCKAP1,GAP43,KIAA1841,RAB30,MAP7D2,GNAO1,WDFY3-AS2,RFFL,SPACA9,GRIN1,LINC01551,RABL2A,RNFT2,MUM1,PADI2,NCKAP1L,AGBL5,ZDHHC15,SMAP1,IDH3A,SOWAHA,USP54,SCIN,KCND2,KCNN3,KIT,L1CAM,STMN1,LIMS1,HECTD2,MBNL1,LDLRAD3,ZNF680,MT3,NEXMIF,FXYD6,NCF2,DNHD1,GPR88,PCDHGC3,CDK18,PFKFB2,NALCN,SNX10,SLC25A23,HMGCLL1,PLXNB1,SEPT4,SH3KBP1,PPP1R1A,PPP2R2C,RASGEF1B,DIRAS2,PTPRN,TUG1,RAB5B,PID1,CEP97,ZNF793,KIF7,SEC61A2,SETD5,YY1AP1,ATP8B4,RPS6KA2,LRRK2,ATAT1,WLS,SCNN1D,TRIM46,FOXRED1,ITSN1,MYO18A,CHD9,ST6GAL1,KANSL3,SLC8A2,CCDC88A,ELMO2,ANKRD36,MBD5,SNRPN,PDZRN3,DOP1A,TNIK,ZHX3,SPP1,KDM4C,PEG10,ZC3H13,NFASC,STAC2,VAMP1,VPS13A,PLCB1,SYT4,ANKRD12,ZEB1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,FAM189A1,CRB1,TGFBR3,TK2,NR2E1,TMPO,BEX4,PIK3R5,TPD52,CDK20,TPM4,ZNF346,TRIO,TRPS1,PPIL6,RFTN2,USP1,VLDLR,TBC1D15,LYPD6,SMARCAD1,DHX33,HPS4,PPP1R3F,WNK2,PARP11,RGS7BP,NUP214,VANGL2,SOCS4" MicroRNA hsa-miR-3164:mirSVR_highEffct hsa-miR-3164:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.98E-87 2.80E-83 2.58E-86 2.37E-85 233 1008 "ASIC2,C3orf14,XKR4,ADAR,FMNL2,TXNDC16,OGT,DPP10,MAP4K3,PHF12,PPFIA2,GPAM,ALS2,PPP4R4,ARHGDIA,STK33,NUMB,DDX3Y,SLC2A11,N4BP2L1,BACH1,MPDZ,SEC11C,PROM1,BMP7,DST,ARHGEF7,C5,PTBP2,RUNX1T1,ZNF501,INA,TMEM257,SEPT7,MAGI1,SYNPR,IGFBP7-AS1,CLCN4,NRXN1,CLU,TJP2,C4orf33,FHL5,CNTFR,AKAP6,SLC4A8,FAM171B,CREM,RNF14,GALNT9,VCAN,SOCS5,PDE4DIP,ZSCAN23,TCAF1,FRMPD4,YTHDC1,TIAM2,NTM,GRIN3A,DTNA,DNAJB6,ABCC9,GOLT1B,FAM135B,EDN3,EDNRB,RASGRP1,MBNL2,EGR3,STX2,IGSF6,SRARP,WAC,CACNG3,ACSL4,FCGR1A,KIAA1109,FGFR1,PRKAG2,CAP2,PDLIM5,ZNF605,DACH2,AP4B1,DKK3,GABRA3,GAD1,GALR1,ZNF559,SRCAP,GGT7,TXNL4A,KDM2B,TDRKH,LPAR4,GRIA4,GRIK2,GRM1,GRM2,PRDM5,GRM7,KIF3A,FAM19A2,AP4S1,WIF1,RASSF8,UBE2QL1,INSYN1,ARHGAP36,ZDHHC15,IDH3A,IDH3B,LRRCC1,LIX1,LRRTM3,JAK1,SLC35G1,KIF5A,LSS,MAT2A,MBNL1,MEIS2,MEST,AFDN,ZNF680,MSRA,PABPC1L2A,NCAM1,ZC3H12B,NF1,SLCO1C1,NPTX2,NRCAM,NUCB2,NUMA1,OLR1,PCDH9,PDGFRA,GPR85,ANLN,SNX10,FAM216A,PLP1,MINDY2,PPP3CB,GRAMD1C,VPS13C,SLC22A23,SIDT1,SNRK,PLPPR1,TMEM260,STK32A,ZIK1,OCIAD1,PEX2,QDPR,MARCH1,OXR1,RADX,GTDC1,FIGN,RGS4,TMLHE,ALG9,ROBO2,RPL15,SPIN3,ZC3H14,KIAA0895L,AMER2,ATXN7,LRRTM4,SCN7A,ELMOD1,ARX,MAGI3,FBXO11,SLITRK3,SEC31A,NUBPL,LRRC55,SLC11A1,SPHKAP,CPEB4,SMARCC2,ANKRD36,SNCA,SNRPN,FNBP1,KDM4C,TEX2,SULF2,ZC3H4,MTCL1,MCF2L,DNMBP,CAMSAP2,ADGRL3,WWC1,VWC2,TCF4,TRIM2,WDR7,PUM2,ZFPM2,ITGB3BP,TGFBR3,GZF1,TJP1,RASD2,RGMB,FNDC5,HIRA,RPL7L1,GORASP1,PLEKHH2,MGAT5B,MEAF6,BEST1,ZNF28,MKRN3,WNK1,DNALI1,RNF103,ADAMTS9,SIGLEC10,SLC17A7,PAK5,HNRNPA3,TRAM2-AS1,SNX14" MicroRNA hsa-miR-23a*:mirSVR_lowEffct hsa-miR-23a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.23E-87 2.94E-83 2.70E-86 2.49E-85 243 1093 "SYN3,SYS1,SLC25A25,ADD2,ADRA1D,C1QTNF1,SRPX,MARCH4,PPFIA4,CNIH2,EPB41L5,VAT1L,CPNE5,LGR5,AQP6,ZFYVE28,ARRB2,CCDC74A,ASTN1,TMEM108,SLC4A4,SLC2A11,CADM3,DPY19L3,ATP6V0A1,ADGRB2,SNAI3-AS1,SEC11C,CFLAR,SCAPER,RAB29,KALRN,SPAG9,USP6,P2RX6,CBFA2T2,SEPT7,ZBED1,CACNA2D2,CFL2,C7orf61,RAB28,COG1,TPP1,MYL6B,DGCR9,SRP14-AS1,TOGARAM2,PNKD,HAPLN1,TRIM69,CSF1,ARHGEF10,SUSD5,VAC14-AS1,KIAA0040,CFAP61,TOX,TBC1D5,INTS1,IST1,AIF1L,DNAL1,YTHDC1,JAKMIP2,C8orf34,PLPPR4,SV2A,MTX3,DLX1,GRIN3A,DMD,HS3ST2,DTNA,DYRK1A,ABCC5,E2F5,OPTN,SUGP2,AASS,EPB41L1,SRARP,SIRPB1,EZH1,TUBB3,CEP78,TOMM40L,PPP1R1B,SEC24B,FGF1,OLFM1,TMEM164,FOXM1,EVL,SEMA4D,FLYWCH1,COQ5,WDR83,ZCCHC17,POMT1,DOT1L,MEGF10,GALNT15,BRPF3,RAPGEF6,LRRC37A6P,ALDH1L1,WASHC2A,GLS,TNRC6A,OS9,ZNF782,GRIA1,GRIA2,GRIA4,GRM7,LINC01551,SOX21,RNFT2,HPS5,CPT1C,HSD17B1,CELF5,ATCAY,EID2B,DOCK7,KIAA1755,ZNF678,INPP5B,KCNJ10,KCNN2,KIF5A,L1CAM,CAMK2N2,GPR155,MAN2A2,ZFYVE27,MARK1,XRRA1,CPNE9,RTL5,NF1,DNHD1,NTRK2,OGG1,PAK3,BEST3,TMIE,ZNF655,KCTD15,JAKMIP1,STRN3,LRP12,MINDY2,PPP3CB,PKIA,PRKCB,PRKCZ,HYDIN,PSMD13,PTPRD,PTPRH,TMEM231,USP47,ENOX1,ZDHHC14,MSANTD2,RFX2,UBR7,ZNF532,GSTCD,EPHA10,SPIN3,MEG3,ABCA11P,HSD11B1L,ATAT1,RTKN,TMEM156,S100B,DGLUCY,ATXN2,TNFRSF19,IL17RB,ITSN1,SH3GL3,HKDC1,AMBRA1,FNDC3A,NLGN1,SLA,CCDC88A,CPEB4,IFT122,SNCB,UNC80,WDTC1,ENKUR,EMC1,TEX2,SPART,SRPK2,SSTR1,ZC4H2,SSPO,ZSCAN29,NSFL1C,SYP,ATP11A,MTCL1,TBX15,ZFP90,CUX2,ZEB1,WDR7,PCDHB9,PSD3,TNS2,FRYL,HIF3A,DICER1-AS1,PRRT1,R3HDM1,C9orf85,DOK6,RGMB,RUSC1,TSC1,RFTN2,HSPBP1,EIF4ENIF1,OSBP2,BEST1,NDRG4,ZBTB38,SPIRE1,URM1,CAB39L,TRIM16L,PARP11,KAT6A,ADAMTS10,LAS1L" MicroRNA hsa-miR-628-5p:mirSVR_highEffct hsa-miR-628-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.69E-87 3.19E-83 2.94E-86 2.70E-85 214 854 "SYN3,EMILIN3,SLITRK1,OLMALINC,SLC44A5,RTL9,TXNDC16,BCAR3,AMT,ANK3,CCDC146,UPRT,DDO,USP37,PPP4R4,LINC00173,DDX3Y,ATP2A2,ATP2B1,BCL7A,BLM,PROM1,CASTOR3,C5,GPC2,CACNA1D,CACNB2,PTBP2,CAMK2G,CAST,USP6,LRBA,CDH10,NUMBL,COPB2,SRSF11,B4GALT6,C4orf33,QKI,NIPBL,TOGARAM2,CHD1L,SEC24C,VCAN,UBXN2A,PHF14,CTNND1,RIMS2,BOC,DOCK4,HDAC9,KATNAL2,ARHGAP24,HP1BP3,MAGI2,GSDME,DMD,HS3ST4,NR1D2,GOLT1B,AASDH,WDPCP,EDN1,KMT5B,EGR3,C8orf37,PAN3,RCAN2,NRN1,RACK1,FER,KIAA1109,FGF1,TMEM164,NBEA,PDLIM5,NPTN,OGA,PHYHIPL,CAB39,MTHFD2,LRRC37A6P,MSTN,SPIN1,MSL3,ZNF638,LOXL3,ADGRA3,GRIA4,PLCD4,GUCY1A2,RASSF8,KLF12,ARHGAP36,HNMT,SMAP1,KIAA1755,PLD5,LIX1,IL6ST,IPO5,KTN1,HECTD2,MAT2A,MBNL1,MDM4,MEIS1,MEIS2,PPM1L,MMP16,MOG,CTNNA3,NAP1L1,NELL2,SLCO1C1,NUCB2,GPR88,CHAMP1,CDK18,ZFYVE21,PLP1,PRIMPOL,STRN3,SDK2,MAGEL2,MED1,RANBP3L,PKIA,MAPK9,HYDIN,SIDT1,PTN,PID1,CEP97,ZNF793,FAT4,SLC6A15,ZMAT4,RFX4,RIC8B,RNASEL,CARF,MRAP2,ATP8B4,STK32B,CNTNAP3,MEG3,ZNF568,TRAPPC13,ATXN2,SCN3A,FOXRED1,NTNG1,HKDC1,CHD9,SLA,SLC6A11,SLCO1A2,ZFP1,MYH15,RCOR3,CMTR2,USP33,SP2,SP4,ATP10B,NKAIN2,NXT2,RGL1,PRRC2C,NUDT10,SYT4,KAZN,ANO4,EHBP1,ACSL6,ZFP90,SZT2,WDR7,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,RNF175,ITGB3BP,AP4E1,HHIP,GZF1,BEX4,TPM4,FNDC5,SLAIN1,GUSBP1,XRCC4,PCDH20,MICU3,KCNT2,TRIM9,ZNF540,ZSCAN26,ANKS1B,SMARCAD1,RNF103,TMEM178A,HPS4,KCNAB1,DOCK8,RNF170,ZDHHC20" MicroRNA hsa-miR-508-3p:mirSVR_highEffct hsa-miR-508-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.85E-87 3.29E-83 3.02E-86 2.78E-85 220 902 "CPNE2,FMNL2,SORCS1,WDR35,OSBPL8,ALCAM,ABCD2,PCDH10,FAM135A,PHF12,ANXA7,UPRT,CDC14B,ZFYVE28,ARSF,CAPRIN2,NUMB,ASTN1,ATP2B1,SLC2A11,SYNJ1,MTMR2,CACNB2,ZNF501,LRBA,SEPT7,CFL2,NDST3,FBXO7,CNN3,SLC4A8,MAGED1,ABI3BP,RTTN,GDA,ATRNL1,PDE4DIP,PUM1,ECE2,ZFYVE16,LIN54,TMEM170A,GIT2,JAKMIP2,MYEF2,HP1BP3,KIAA0753,MAGI2,AK5,KBTBD11,CDON,ACOT8,EDIL3,SEMA3D,PCOLCE2,COQ7,KCNMB2,NCALD,ETV1,PIPOX,RTN3,NRN1,F3,F8,DLC1,FCGR1A,POLK,HVCN1,PHYHIPL,SULT1C4,MSTN,ADAM28,GGTA1P,GK,DBF4,MSL3,FERMT2,GPR37,CECR2,RAPGEF4,GRIA2,GRIA4,GRIK2,SERP2,GRM5,GRM8,RNF165,GSTT2,MAEL,ZHX1,ZDHHC15,HSD17B1,BRINP3,LRRTM1,KCNA6,KCNK1,STXBP5,MARK1,MAT2A,MBNL1,SRSF12,MITF,MOBP,CD200,ERICH3,ZNF680,NRBP2,NEK1,NEUROD2,NF1,NFE2L2,NOVA1,NUCB2,OLR1,OXTR,CNTN3,PCMT1,GPR173,PLP1,PURG,TRHDE,MAPKAP1,LRP12,SCHIP1,PMS2,EPB41L4B,MINDY2,MASP1,CNTLN,PTPRD,EML5,PPP2R3C,TMEM255A,USP47,RAD52,OXR1,RASGRF1,DBX2,RBBP6,RGS12,SLC25A36,PBRM1,RPRD1A,KLHDC8A,RAVER2,CARF,RORB,ELP2,CCDC102B,RPE65,ARMH4,UEVLD,PTGR2,ATAT1,CLIP1,ZNF568,SAFB,SATB1,SCN2A,SCN8A,ZFP2,SGK1,CPEB3,CHD9,NUBPL,ABLIM3,PPP4R3A,ATF7IP,ZFP1,SORCS3,ANKRD36,LIMCH1,SNRPN,PALLD,UHRF1BP1L,IDI2-AS1,LMO3,C11orf87,SRPK2,SSTR1,TTBK2,SYPL1,UNC5D,ADGRL3,SATB2,ZEB1,TRIM2,WASHC4,CLASP1,SYNE1,ARHGEF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,CRB1,SLC44A1,KAT6B,TPM3,TTC3,PLEKHH2,ZIC3,KCNT2,TRIM9,FTSJ1,LAMP5,RNF103,CIAPIN1,TMEM163,NELFE,C12orf4,PHTF2,NETO1,CBLN2,SENP7" MicroRNA hsa-miR-494:PITA hsa-miR-494:PITA_TOP PITA 6.92E-87 3.89E-83 3.57E-86 3.29E-85 176 574 "XKR4,CSMD3,DSCAML1,ADCY6,SLC12A5,USP31,ESYT2,INTS2,GPR158,KLHL13,PCDH19,HACE1,OSBPL6,FAM135A,LCORL,API5,SHTN1,ARHGAP5,ARNTL,ZBTB10,SLC4A4,B3GALT2,ARHGEF7,CAMK2D,CANX,CAST,CH25H,TMEM257,SOCS6,CHN1,KIAA1549L,CLTA,CNN3,CNR1,AKAP7,CLOCK,RBM39,SOCS5,DZIP3,APPL1,CTNND2,DBN1,JAKMIP2,MFAP3L,ZC3H11A,RHOBTB1,G3BP2,DLG2,DMD,ABI1,EDN1,YAF2,FAM13A,MBNL2,KMT5B,EGR3,EIF5,PAN3,EN2,RCAN2,ERBB4,ACSL4,TAOK3,SCML2,SEC24B,ACTL6B,FHL1,SYNCRIP,NBEA,TACC2,STAU2,PHYHIPL,GABRA5,ATP8A2,PPARGC1A,TNRC6A,RAB40B,PRRC2B,PCLO,GRIK2,KIF3A,ADAMTS6,HAS2,ELOVL5,C5orf24,IGSF1,KCNA1,KIT,IPO5,INSYN2,LMO1,MAT2A,LRP1B,MN1,MSI1,NEXMIF,NAP1L3,ZC3H12B,NELL1,NEUROD1,CNOT4,NOVA1,PCSK1,PRTG,PDE4B,PDGFRA,NXPH1,POU3F2,PPP2R2B,CEP41,PTPRB,RAB5B,TMEM255A,FEZF2,MSANTD2,RGS7,PBRM1,ZFHX4,ZNF532,RPL15,LGR4,ELMOD1,RASA3,NLGN4Y,SCG5,CHD9,FBXO11,FHOD3,WDR37,SLC8A2,TET1,SMARCE1,MBD5,SOX11,SP4,NMNAT2,KDM4C,EPB41L3,CEP68,STAC2,SYNE2,PLCB1,SYPL1,TAC1,TACC1,MTCL1,CAMTA1,PHF24,RALYL,ARHGEF12,SIRT1,ZFPM2,HHIP,TIAM1,ERCC6L2,TRPS1,SGK3,CADM1,FAM155A,PITPNB,WIPF1,ZIC2,REEP1,TMEM237,POLR3H,LAMP5,SLC30A4,EVI5,RNF103,WIPF2,KAT6A,HNRNPA3,CERS6,DPF3,RNF146,SOCS4" MicroRNA hsa-miR-489:mirSVR_highEffct hsa-miR-489:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.25E-87 4.07E-83 3.73E-86 3.44E-85 221 911 "KLHL32,CCDC85A,MTUS1,KLHL13,HACE1,CC2D2A,TAOK1,LRRC7,SEMA6A,SYT13,MAP4K3,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,ANXA7,LGR5,TMEFF1,ZSCAN18,ZBTB10,NCOA1,NUMB,ATM,ATP1B3,ATP2B1,CA12,CACNA1D,CACNA1E,CALB2,KALRN,PTBP2,SPAG9,LDB2,ZMYM4,LRRFIP1,CFL2,SRSF11,CHN2,RAB3C,JAM2,NDST3,PPT2,FBXO7,C4orf33,AKAP6,SLC25A27,AHCTF1,ZNF521,ZFP28,OSBPL3,GREB1,CFAP61,CTNND2,KATNAL2,RIPOR2,SPOCK2,GIT2,JAKMIP2,RHOBTB1,SPOCK3,RABGAP1L,GRIN3A,NYAP1,CPEB2,DMTF1,DNM1L,KLHL5,FRY,PHF20L1,ELAVL2,PCOLCE2,TMEM35A,PAN3,EMX2,EYA1,CLVS1,CACNG3,TAOK3,TOMM40L,SLC9B2,PRKAG2,SMC2,CELF1,MEGF10,DISC1,NEU3,SULT1C4,GK,GLDC,GPR22,GRIK2,LINC01551,AP4S1,WIF1,ARHGAP36,HNF4G,TCEAL6,SCIN,KCNN1,KCNN2,IPO5,LAMP2,SMAD9,MAT2A,MID1,MITF,MOBP,ERICH3,MRPL42,SCG3,HS6ST3,MXI1,PABPC1L2A,NF1,NPR2,PCBP3,NRCAM,P2RX7,PAK3,PDE1C,PDE4B,PDE4D,PDE1B,GPR85,PFKFB3,NALCN,NOMO2,PMP2,MAPKAP1,LRP12,MED1,MINDY2,PPM1B,CEP41,CNTLN,BDNF-AS,PTN,TMEM260,ACSM5,QDPR,CEP97,PLEKHB2,RAP1GDS1,RBBP6,ZDHHC14,GTDC1,FIGN,RFX3,RFX4,RIC8B,CCDC82,CARF,GSTCD,LRRK2,CNTNAP3,ZNF568,SCN8A,SELL,SCG5,MAGI3,NLGN1,ST3GAL3,ANKRD6,SLA,PPP4R3A,SLC8A3,ARHGEF40,SLC12A4,NAPB,SMARCA4,SMARCC2,SMARCE1,RIMS1,MBD5,SON,ZSWIM8,EMC1,UHRF1BP1L,MYCBP2,KIF1B,C11orf87,SRPK2,ITPRID2,CEP68,DIP2A,NSFL1C,PRRC2C,PLCB1,ANKRD28,ANO4,WASHC4,SYNE1,USP32P1,ITGB3BP,ZMAT3,HHIP,TLL2,HEY2,TMPO,TP53BP2,TPM3,ZMYND8,VSNL1,GUSBP1,XRCC4,ZFP37,ZNF711,ZNF19,ZNF28,EML6,SCG2,MPPE1,SLC17A6,MVB12B,C12orf4,EPM2A,FAM13C,PAK5,CASC15,FXR1,SLC4A10,SENP7" MicroRNA hsa-miR-1269:mirSVR_lowEffct hsa-miR-1269:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.34E-87 4.12E-83 3.78E-86 3.48E-85 265 1289 "SERPINA3,ASIC1,EMILIN3,NBAT1,SYS1,ADAR,ADD2,SLC44A5,KIAA1324,SPARCL1,SPOP,GOLGA7B,FAM135A,MYH7B,DGKZ,SHROOM2,MIER1,RGS20,MARK4,ASPH,ASTN1,EIF4G3,STX16,DPY19L3,RGS11,CASTOR3,GPC2,CA8,KALRN,VXN,CAST,DCLK1,IGFN1,UBE2L6,NPIPA1,SOCS6,PPT2,CLCN3,KIAA1549L,FAM19A5,NIPBL,CNGA3,FHL5,AKAP6,LETMD1,SMARCAL1,ZFP28,MFSD4A,NECTIN3,ZNF385A,CLOCK,PREPL,CREB5,GDA,ABCG1,ARHGEF10,ATRNL1,PHF14,RUBCN,CCDC144A,ARHGAP32,DNAJC6,ZEB2,TMEM130,KIF19,GRIN3A,OLIG1,NR1D2,DMTF1,DPP6,ACOT8,DSCAM,DTNA,AASDH,EDNRA,SGK2,SYT15,RASGRP1,KLHL5,PHF20L1,PLEKHA1,TMEM35A,EN2,SEZ6,MRPL37,CDKL3,SIRPB1,FAM198B,ZNF461,PTK2B,STRADA,SEC24B,FOXG1,FLT1,COQ5,TMEM175,KHDRBS3,B3GAT1,MPP6,ZMAT1,MEGF11,DKK3,GABRB1,GABRG1,AHCYL1,FAM120B,GALC,RAPGEF6,GAP43,GPR162,GFAP,PCDH11X,STON1,EML4,RAPGEF1,GRIA1,GRM3,GRM5,ZNF496,IL1RAPL1,LINC01551,PADI2,HNMT,LRRC75A,ZNF546,IGF1,KNDC1,TJAP1,SLC6A17,ITGAV,KCNA1,OLFM3,KCND1,KCNJ3,KLC1,LAMP2,SYTL4,NCOA7,MAP4,MARK1,MAT2A,AFF1,MOBP,N6AMT1,MYO6,P2RY13,NRCAM,NTRK2,OPCML,OPHN1,PCMT1,PDE4B,PDGFRA,GDAP1L1,NALCN,KCTD15,PLTP,MTRF1L,ANKRD16,PMP22,CDIP1,SCHIP1,PPM1B,PPP2R2B,CRLS1,PRKACB,CEP41,GRAMD1C,HYDIN,PRPSAP2,VPS13C,MTMR10,C1orf109,IQSEC3,NWD1,ARID4A,BSDC1,DPF2,RFX2,CARF,PCMTD2,SNX22,TCP11L1,CNTNAP3,FAM161B,HUNK,KCNIP3,ZNF331,LINC00461,TNFRSF19,SOX6,TRIM46,TRA2B,DOCK10,CHD9,FNDC3A,NLGN1,ANKRD6,SLA,LRRC55,ARHGEF40,SPHKAP,CXXC4,SORCS3,CDK5RAP2,RCOR3,FAIM2,PALLD,PDZRN3,MYO16,DOP1A,PDZD2,SOX1,ZCCHC24,UHRF1BP1L,KDM4C,ZNF423,NFASC,SRPK2,TAB2,LRRC4,INKA2,COBL,ANKRD28,TAC1,MMS19,ADGRL3,ANO4,ARHGEF12,FRYL,TEK,CRB1,BHLHB9,BEX4,RIMBP2,PRRT1,C5orf64,KAT6B,RBFOX2,TPM2,TRPC1,TRPM2,ZMYND8,PPIL6,DCBLD1,RFTN2,ZKSCAN5,CLHC1,TBC1D15,WIPF1,KLC2,SF1,ZIC3,KCNT2,TRIM9,CRB2,ZNF154,FSTL5,PRDM10,SLC17A7,FBXO36,FAM219B,TIGD6,FXR1,SENP7" MicroRNA hsa-miR-302e:mirSVR_highEffct hsa-miR-302e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.09E-87 4.55E-83 4.16E-86 3.83E-85 241 1078 "KIAA1211,PTCHD1,MTUS1,GPR158,AK2,SPOP,ALCAM,ANK2,PHF12,API5,APP,STK33,ASPH,STX16,DPY19L3,BACH1,DCAF5,CFLAR,ST3GAL5,MTMR3,JAZF1,CA12,CALB2,AIFM1,MAGI1,CFL2,CHN2,TAOK2,ABCG2,C4orf33,AKAP5,ACBD5,IGDCC3,CNRIP1,ZNF385A,CRHBP,ANKRD44,FEZ2,ARHGEF10,SOCS5,CYBB,BOC,TOX,DGKG,DCC,ZNF804A,MYEF2,HP1BP3,BLOC1S6,ZC3H11A,HS3ST4,HS3ST2,DMTF1,DRD1,ABCC9,E2F5,EDNRB,ANKRD46,HIPK3,EGFR,KMT5B,GOLGA7,IRAK4,ELAVL2,PLEKHA1,C3orf18,DCTN4,EPHA5,EPS8,DNAJC27,CORO2B,MED12L,POLK,SUCO,NELFCD,USP16,MSANTD4,ZMYND11,ARPP21,IGSF5,TUBGCP4,GGTA1P,COPS8,TNRC6A,GLUL,MAP7D2,GPM6A,GPR12,GPR34,PCLO,GRIA1,GRM5,TMEM25,HPS5,TLX1,MSL1,IDH3B,JAK1,OLFM3,KCNMA1,KCNN2,SYTL4,HECTD2,NCOA7,ZNF667-AS1,MARK1,SRSF12,PPM1L,POC1B,MYCN,MYO9A,NACA,NELL2,NEUROD1,NF1,SLCO1C1,NRCAM,NUMA1,OCRL,OGG1,OPHN1,PCDH9,PDCD2,PFKP,ZDHHC8,PLCL1,JAKMIP1,PRIMPOL,TRHDE,PRRX1,ING3,SPATA6,DRAM2,PPP2R5C,PRKACB,PKN2,GRAMD1C,MASP1,SNRK,PTHLH,PXK,TMEM260,PTPRD,PTPRO,CEP97,FAT4,ENOX1,OXR1,ARID4A,RDX,SLC6A15,CRTAC1,TRIM68,GTDC1,RFX3,RIC8B,RNASEL,RNH1,ZNF532,CARF,TMEM100,MCMBP,LGR4,RPS20,AMER2,SCN2A,SHC4,MAGI3,FBXO11,FNDC3A,SLITRK3,CLSTN1,WDR37,PPP4R3A,RAB3GAP1,ARHGEF40,SLC14A1,SLC15A2,TET1,ZFP1,SMARCC2,RCOR3,CMTR2,UNC80,RBM34,MYT1L,TNIK,ZC3H13,ZBTB43,LMO3,ATP10B,RGL1,STXBP1,FGD4,SYNE2,DNAJC9,CAMTA1,UNC5D,TBCEL,CUX2,ZEB1,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,CRB1,C18orf54,ITGB3BP,LEFTY2,AP4E1,AKTIP,TIAM1,NR2E1,TNS1,RGMB,TRPS1,PPIL6,PITPNB,VLDLR,FMN2,LYPD6,LAMP5,SYNC,CADM2,RGMA,PRDM8,PRDM10,NELFE,PLSCR4,FAM13C,MARCH8,PAK5,FAM219B,NLRP3,IFT88,DPF3" MicroRNA hsa-miR-342-5p:mirSVR_lowEffct hsa-miR-342-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.53E-86 8.56E-83 7.83E-86 7.21E-85 237 1047 "ASPHD1,CLK4,ADARB2,GALNT13,SLC12A5,KIAA1211,AP2A2,AP1B1,ALAD,SPOP,PITPNM2,AMPD3,PPFIA4,CNIH2,SUGT1P4-STRA6LP-CCDC180,GPAM,PPFIA3,TMEM263,ARNTL,ATP2B1,ALDH7A1,N4BP2L1,ATP6V0A1,ADAM15,RGS9,FGF17,ARHGEF7,C1QC,CACNA1I,CFAP410,CA12,CACNA1B,KALRN,CAMK2D,VSTM2A,CAST,BRSK2,P2RX6,AIFM1,ENTPD6,DGKI,ZMYM4,EVI5L,CRLF1,NUMBL,ASIC3,ARMC8,COL11A2,CLIP3,RGS6,LRRC3B,MICAL2,OSBPL3,FAM169A,SLITRK5,CTH,NRSN1,PPP6R2,RUBCN,GAPVD1,RASSF2,GIT2,PITPNC1,JAKMIP2,ZEB2,SV2A,DLG4,DMPK,MED12,DYRK1A,SEZ6L2,SGK2,SIDT2,EFNA3,EGFR,RASA4,SORBS3,ING4,TNK2,DMTN,RASGRP2,RABEPK,APC2,NRN1,CLVS1,WAC,ATP8A1,RACK1,ZMYND10,STRADA,KAT8,FECH,FGF14,FOXM1,NELFCD,DPYSL4,DLL3,TMEM151A,DOT1L,ZMYND11,B4GALNT1,ERAP1,CPLX2,ALDH1L1,GGT7,C1QL1,RNPS1,GNAS,GNG4,SERP2,GRIN1,GRM1,GSTM5,RABL2A,GUCY1B1,ATOH8,PADI2,PTGDR2,AGBL5,HPCA,CPT1C,HSD17B1,CELF5,SMAP1,FAM95B1,GATD1,KIF5C,KIT,L1CAM,TTYH2,MAG,MBNL1,SYT9,LDLRAD3,MT3,MYO6,FXYD7,NCAM1,NPTX2,OGG1,DPY19L2P2,ETFRF1,ZDHHC8,NLGN3,NOMO2,FTO,MAPKAP1,SEPT4,EPB41L4B,PPP3CB,MAPK4,WBP1L,SIDT1,MDGA2,PXK,CASTOR1,ACSM5,ZSCAN2,TMEM231,RALGDS,SH3TC2,IQSEC3,GTDC1,RFX2,TTLL7,RIC8B,ROBO2,STK32B,FAM182A,FOXRED2,TRIM46,ITSN1,FERMT1,NTNG1,AMBRA1,ST3GAL3,SLC1A7,SMTN,FAM214B,SLC11A1,SCMH1,SLC20A2,MAST1,SNCB,FAIM2,SNRPN,PALLD,KDM4B,KIF21B,ZSWIM8,NMNAT2,ERC1,CDK19,MCF2L2,LMO3,SRPK2,PBLD,INKA2,MAPK8IP3,DIP2A,STAC2,KANK1,KLHL7,SYP,COBL,MCF2L,CUX2,TCF7,SZT2,AZIN2,SYNE1,RALYL,FRYL,HIF3A,ATP13A2,CDH22,R3HDM1,C5orf64,KAT6B,TPD52L2,RASD2,SYNPO2,AMACR,ANO5,BCL2L13,VAV1,DPYSL5,SH3GLB2,NT5M,PRDM8,SNX27,LINC00632,PCBP4,PARP11,DOCK8,VANGL2,ST8SIA2" MicroRNA hsa-miR-29c:mirSVR_highEffct hsa-miR-29c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.83E-86 1.03E-82 9.37E-86 8.63E-85 241 1082 "KCNH8,RBM10,NCKAP5,KDM5D,XKR4,CDC7,GRAMD1B,PTCHD1,OSBPL6,TXNDC16,BCAR3,ALK,AMPD3,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APC,GPAM,BCAS1,TMEFF1,CDK13,CAPRIN2,ASPH,BRINP2,STX16,ATP2A2,ATP2B1,N4BP2L1,RIPK1,ADGRB2,PROM1,DST,NAE1,WASF1,MMD2,PTBP2,CAMK2D,VSTM2A,RUNX1T1,C1orf52,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A7,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,GDA,CRYM,CS,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,DNAJC6,ZEB2,RHOBTB1,SV2A,GRIN3A,DYNC1I1,DNM1L,WDPCP,EDNRB,FEM1B,SH3GLB1,PHF20L1,EGFR,KMT5B,SORBS3,ELN,TUBD1,ANKRD13B,RTN3,SCML2,EFEMP1,MED12L,MEX3B,RGPD5,DCTN2,TPK1,ATP2C1,NSG1,PNMA2,OGA,FYB1,STAG2,DKK3,GABRG2,ARPP21,DISC1,SESN1,GK,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,EML4,GPR37,PCLO,ADAMTS6,ZHX1,HRH3,VSIG4,HMGCR,HNF4G,HNRNPK,HTR2A,IGF1,IGSF1,SCIN,ZNF678,LRRTM3,KIF5A,LAMA2,LIMS1,HECTD2,MAP6,MEST,MYCN,MYO9A,NEXMIF,NAP1L2,NAP1L3,NASP,NCAM1,NRCAM,OPHN1,PDGFRA,ENPP2,GNG2,CCSER2,PLP1,HMGCLL1,PURG,PMP22,ING3,EPB41L4B,POU3F2,PRKAB2,RASGEF1B,SLC26A11,GRAMD1C,VPS13C,SNRK,PTHLH,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,ROBO1,PCMTD2,FBXW7,SALL1,SFPQ,TRA2B,SGK1,SH3BGR,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,RAB3GAP1,SLC12A2,NAPB,BTBD7,TET1,ZKSCAN3,RIMS1,MYO16,HECW1,SPTAN1,KIF1B,NPAS3,TAB2,NXT2,ZSCAN29,ELOVL4,FGD4,PRRC2C,VPS13A,SYP,ANKRD12,DDHD2,TBCEL,TCF4,WDR7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,HEY2,TPM1,TRPC3,FNDC5,TSN,TUBB2A,CLHC1,UGT8,VLDLR,ZNF19,ZNF28,TRIM9,ZNF45,EML6,DPYSL5,PLPPR5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,NAV2,IFT88,FAM198A" MicroRNA hsa-miR-1271:mirSVR_highEffct hsa-miR-1271:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.04E-86 1.15E-82 1.05E-85 9.63E-85 209 820 "ABAT,ASPHD1,XKR4,KLHL32,ADCY6,ADD3,SLC12A5,KIDINS220,SLC24A4,KIAA1324,C1QTNF3,LRRC7,ABCD2,ALK,AMPD3,LRCH2,FGD2,C6orf89,UPRT,VAT1L,STK33,BRINP2,DPY19L3,ADGRB3,DST,ARHGEF7,JAZF1,CACNA1E,CACNB4,THSD7A,PTBP2,CAST,LDB2,CCKBR,LGI1,MAGI1,CACNA2D2,CHM,NDST3,LY86,NIPBL,CNN3,COL9A1,ABI3BP,MYRIP,LRIG1,ERC2,APPL1,CTNND1,ECE2,HDAC9,ARHGAP24,FRMPD4,TM9SF4,DGKG,C8orf34,ZEB2,HP1BP3,PLPPR4,DSCAM,GNE,E2F5,EDNRA,FAM13A,PHF20L1,LPAR6,CALCRL,GPHN,SRRM1,ZNF585B,FDFT1,FHL1,CAP2,FOXF2,NOP56,SMC2,FAM49B,ST6GALNAC3,NSG1,FYN,GAD2,BRPF3,B4GALNT1,NCKAP1,GAP43,DISC1,KIAA1841,SPIN1,GLS,PCDH11X,ZNF782,GPM6A,GPM6B,LILRA1,GPR12,GPR22,RAPGEF4,GRIA1,GRID1,NR3C1,GRM7,KAT7,RASSF8,HAS2,ZHX1,ELOVL5,HNMT,OPALIN,HSP90AA1,C2orf72,KTN1,FGFBP3,ARHGAP12,MBNL1,TM6SF1,MEIS1,MITF,WDR49,ZNF680,MRPL42,TAGLN3,HNRNPM,NF1,NOVA1,DNHD1,IGSF11,PCSK5,PDE1A,PFKFB3,PIK3C2A,ANLN,FAM216A,PDZRN4,MAPKAP1,PRRX1,EPB41L4B,SH3KBP1,MED1,CRLS1,PTPRB,PTPRO,CEP97,RASGRF2,BSDC1,RIC8B,ZFHX4,BAALC,MCMBP,SOX6,TRIM46,MRAS,SUPT20H,MAGI3,FHOD3,SYBU,CTXN2,DZIP1,NUBPL,FAM81A,PPP4R3A,BTBD3,SLC6A9,RAB3GAP1,IFT122,MYO16,TRERF1,SOX5,SOX10,SP4,KIF1B,EPB41L3,LRRC4,SS18,ADHFE1,AJAP1,KLHL7,JMJD6,ZFR2,TAC1,FBXW11,TBL1X,TBX15,SIN3B,TCF7L2,ZEB1,SLC19A3,PCDHB6,SIK3,TF,FAM200B,TIMP4,TPM1,RUNDC3B,TRPC3,DCBLD1,ANO5,RPL7L1,SLAIN1,VLDLR,ZIC3,TRIM9,ZBTB38,TMEM198,ZFAND5,NAV3,JMJD1C,NETO2,SLC4A10,GAN" MicroRNA hsa-miR-203a-3p.1:TargetScan hsa-miR-203a-3p.1 TargetScan 2.52E-86 1.42E-82 1.29E-85 1.19E-84 189 670 "ARID1A,NDRG3,FMNL2,BRAP,KIAA1211,KCTD16,OSBPL1A,OSBPL8,BCAR3,AMPD3,MAP4K3,PHF12,APC,FAM131A,CASK,ARNTL,CDK13,MARCH3,INSYN2B,ATM,BCL7A,LDHD,BMPR1B,DST,BTRC,FOXK1,CALM1,PTBP2,RUNX1T1,CDH10,CFL2,KMT2C,PLAA,CLCN3,C4orf33,HECTD1,MAP4K4,HOMER3,CNTFR,RTTN,NRG2,CLOCK,RBM39,HAPLN1,MICAL2,RIMS4,PLXNA4,APPL1,PLCXD3,HDAC9,PHF19,MATR3,DGKB,MYEF2,FBXL5,CHRDL1,NR1D2,DYRK1A,DNM1L,EBF1,EDN1,FAM135B,EDNRA,HEYL,MBNL2,EGR3,RGS17,EN2,EPB41,EPB41L1,NCALD,ETV1,MRVI1,NBEA,NSG1,MSANTD4,FYN,MEGF11,GABRA1,GALNT15,CAB39,GAD2,NCKAP1,ATP8A2,PCDH17,GHR,RAB30,GPR75,GLS,GNG4,NUDT21,RAPGEF4,RAPGEF1,IL1RAPL1,GUCY1A2,NXPH3,NEGR1,MSL1,NKD1,LRRCC1,LRRTM3,KCNB1,CLVS2,KCNN3,KCNQ3,KIF2A,ARHGAP12,GPR155,MAPT,MBNL1,CHIC1,MEIS1,MEIS2,MGAT3,AFF1,MXI1,MYO5A,PABPC1L2A,NFYA,NOVA1,OPA1,KCNK10,PDE4D,GPR85,FAT3,NXPH1,RANBP3L,PRKCB,MAPK8,MAPK10,GRAMD1C,CNNM2,PTCH1,EML5,PTPRN,REV3L,GTDC1,FIGN,KLHL11,RAVER2,ROBO1,ROBO2,ACER3,RIMKLA,SALL1,FNIP1,ELMOD1,DOCK10,CHD9,BTBD3,DHX30,CCDC88A,BTBD7,CPEB4,RIMS1,MBD5,FAM126B,SCN3B,KIF21B,NMNAT2,RAP1GAP2,CLSTN2,FAM168A,NECAB1,ADAMTS17,ATP11A,KAZN,CAMTA1,CAMSAP2,KIAA0930,RPGRIP1L,DOCK9,PUM2,DICER1,ITGB3BP,CBX5,DDHD1,KAT6B,RPRM,FAM155A,FRRS1L,CADM2,PRDM10,NAV3,C12orf4,KAT6A,CERS6,NETO2,GAN" MicroRNA hsa-miR-335:mirSVR_highEffct hsa-miR-335:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.83E-86 2.15E-82 1.96E-85 1.80E-84 217 886 "NCKAP5,CCDC85A,CDC7,SORCS1,AP2A2,TXNDC16,APAF1,VAT1L,SHROOM2,CDC14B,CDK10,CDK13,STK33,ASPH,ZBTB10,NCOA1,ATM,ATP2B3,SCAPER,CA8,CERS5,TMEM257,CD38,LRBA,CDC42,LGI1,NDST3,KMT2C,RAB33A,NRXN1,COG1,NGEF,FBXO7,TJP2,NIPBL,ARMC8,AKAP6,BTF3L4,SLC4A8,AHCTF1,ZFP28,CNRIP1,MFSD4A,SLC35F1,FAM171B,HINFP,MICAL2,OSBPL3,DZIP3,ERC2,CTH,ARHGEF4,FAM131B,DOCK4,DCAF8,LONRF1,DGKB,DAPK1,PABPC5,SPATA2,ZNF804A,C8orf34,HP1BP3,KIAA0753,DDX46,G3BP2,FAM107B,ABCC5,EBF1,ATL1,FSD1L,YAF2,PHF20L1,SUGP2,RASA4,ELAVL3,VPS13B,EPB41,CEP85L,TMEM74,RCSD1,GORAB,FGF13,SUCO,C1orf61,FLT1,UFM1,CAMKK2,CELF1,STAU2,DKK3,GABRB1,RAPGEF6,KIAA1841,GFAP,RND1,GLYR1,KDM2B,RAB40B,PRUNE2,STMN2,KAT7,PSIP1,GUCY1A1,ZHX1,NXPH2,HMGCR,ZNF546,INPP1,KCNC1,KIT,ARHGAP12,LSS,C2orf80,MAP6,MAT2A,MBD1,TM6SF1,AFDN,MTTP,RSPO2,NACA,HNRNPM,NAP1L2,NF1,SLCO1C1,NTRK3,NUCB2,PAK3,PCDH9,A2ML1,TMEM38A,PLIN1,PRIMPOL,EPB41L4B,NXPH1,MED1,CRLS1,PPP2R5C,PPP2R5E,RANBP3L,PRKCB,MAPK9,MAPK10,DIRAS2,APTX,OCIAD1,PTPRH,FAM66C,RBBP6,ERI2,FIGN,RNASEL,ZFHX4,ZNF532,SETD5,ROBO1,ELP2,PRR5L,MAP6D1,PTGR2,SALL1,SELL,SUPT20H,TRA2B,SYBU,PAAF1,SEPHS1,SLC12A2,SNRPN,MYO16,SON,SOX2,ZSWIM8,KDM4C,ZBTB43,SSTR1,ZC4H2,STAU1,AJAP1,DNAJC9,PJA1,DDHD2,TMEM136,KLHL4,TCF4,SATB2,TEX15,SIK3,ITGB3BP,AP4E1,TK2,FAM124A,RBFOX2,SYNPO2,AMACR,TRPC1,RPRM,UBE2H,LGI4,FMN2,ZBTB16,SYNC,PRDM2,XKR7,PRDM10,VPS35L,PDSS2,RGS7BP,GOPC,DNAH10,SMIM8,ZNF248,NHSL1,SLC39A12,NETO2,SLC4A10" MicroRNA hsa-miR-621:mirSVR_lowEffct hsa-miR-621:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-86 2.70E-82 2.46E-85 2.26E-84 203 777 "ACADM,ACTN2,FMNL2,KLHL32,NLGN4X,PCDH19,OSBPL6,WDR35,CC2D2A,AK2,ADGRF5,FAM135A,ZFAT,LRCH2,FGD2,PPFIA4,PPFIA1,UPRT,GPAM,ALS2,USP37,LGR5,AQP6,CDK10,ARNTL,ASPH,CALM1,CANX,BRSK2,USP2,TIGD7,KMT2C,NRXN1,CNN3,SEC31B,ABCG1,CST3,ARHGAP32,RASSF2,TBC1D5,KCTD8,MAML1,TMEM170A,AIF1L,ARMCX4,ZEB2,DMD,DPP6,DRP2,ATN1,PDCD6IP,ECM2,TOM1,DNM1L,ANKRD46,OPTN,PHF20L1,MRO,EIF4G2,ELAVL2,OLIG2,ANKRD13B,SRRM1,EFS,CEP85L,DUSP27,EXTL2,MRVI1,NRN1,FCGRT,STRADA,MED12L,AMOTL2,POLK,CAP2,FOXO3,ANKFY1,CAMKK2,KHDRBS3,CELF1,DACH2,PNMA2,DKK3,GALC,MTHFD2,GATM,ALDH1L1,MSL3,PCDH11X,STARD3,RAB40B,LOXL3,FERMT2,TDRKH,EML4,TMEM25,LINC01551,TOX2,PADI2,NXPH2,FRMD3,FAM95B1,MYLK2,NKD1,KIAA1755,INSM1,KCNJ16,CREG2,KIF5C,LINC00634,KLC1,LAMP2,MAP6,MAT2A,AQP11,CHIC1,MEF2C,MEIS2,KITLG,MMP16,MOBP,LYRM9,MYO6,MYO7A,NCF2,SETD4,GPR137C,DPY19L2P2,SNX10,GPSM2,JAKMIP1,PLXNB3,POU6F1,MINDY2,PTPA,RANBP3L,PRKCB,GON4L,PIGG,CNTLN,PTPRD,PTPRE,PTPRZ1,PEX2,TUG1,CEP97,RALGDS,ENOX1,RBBP6,RDX,ZMAT4,TTLL7,SEC61A2,RNASEL,NEK11,FBXW7,PRR5L,MIR124-2HG,ATXN2,SUPT20H,TRA2B,NLGN4Y,ARX,CPEB3,SLITRK3,ST3GAL3,KBTBD4,SLC12A2,SLC14A1,MBD5,SNRPN,SCN3B,KDM4C,RBM26,C11orf87,TAB2,ZC4H2,NSFL1C,ACSBG1,FGD4,ATMIN,TPCN2,TCF12,AZIN2,TMEM151B,RALYL,GPRIN3,SIRT1,CRB1,LEFTY2,AP4E1,RGMB,FAM155A,WIPF1,ZBTB14,ZNF24,SLC26A10,REEP1,PLPPR5,MVB12B,EPM2A,ACTR3B,ST8SIA2" MicroRNA hsa-miR-624*:mirSVR_highEffct hsa-miR-624*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.63E-86 4.29E-82 3.90E-85 3.59E-84 206 802 "RALGAPA1,CLK4,NBAT1,CSMD2,CSMD3,CCDC85A,ADD3,AXIN2,ERMN,ADORA3,DPY19L2P4,NLGN4X,AP2A2,ZNF608,OSBPL1A,WDR35,PCDH10,UNC79,ANK3,MAP4K3,USP28,PARG,APP,CDC14B,PPP4R4,SPTBN4,ZFYVE28,ARNTL,ASPH,CCDC181,RIPK1,DOCK11,DDR1,CBLN1,KRIT1,DGKI,CDH2,CDH18,LGI1,LOC730101,MAGI1,CFL2,CHN1,COL4A5,CNRIP1,CHD1L,CLOCK,CRMP1,RNF14,MICAL2,CSNK1G3,ERC2,DCAF8,ZFYVE16,LONRF1,LIN54,COPS7A,MAGI2,FBXO25,ZNF582-AS1,CHRDL1,DLG3,NR1D2,SLC25A18,ABCC5,DNM1L,GOLT1B,AASDH,SH3GLB1,KMT5B,EIF1,F3,F8,WAC,SCML2,RACK1,FER,POLK,SEC23B,NBEA,SMC2,STAU2,MSANTD4,GABRA3,GAD1,ARPP21,GART,GHR,GLI2,HTATSF1,GNAS,PRUNE2,GPM6A,PCLO,KAT7,MAEL,HSF2,LINC00667,MYLK2,DOCK7,ZNF385B,SLC35G1,METTL21A,HECTD2,ARHGAP12,NCOA7,MAN2A2,MBNL1,TM6SF1,KITLG,MITF,XRRA1,MOV10,PABPC1L2A,NCAM1,NDUFA5,NELL2,NF1,NFE2L2,OMG,OXTR,ETFRF1,PCDH8,PCSK5,PDGFRA,CYTL1,MTRF1L,SH3KBP1,POU3F2,GRAMD1C,HYDIN,DCHS2,TMEM260,PTPRB,PTPRE,RAD17,FAM184A,RAP1GDS1,OXR1,RBBP8,RDX,NUDT11,ZNF532,SETD5,CARF,ELP2,TMEM100,FBXW7,ZNF568,RYR3,FOXRED1,ST3GAL3,NUBPL,WDR37,FAM214B,CCDC88A,SLC12A2,MTERF2,SLC20A2,TET1,NAXD,MBD5,PALLD,UNC80,SON,SOX5,UHRF1BP1L,ZC3H13,TSPYL2,TAB2,NXT2,RGL1,VPS13A,SYPL1,SYT1,PJA1,MCF2L,ADGRL3,VWC2,SATB2,SZT2,FRYL,CCDC173,FAM200B,SIRT1,AP4E1,AKTIP,TLR4,ZFP91,METTL3,PRMT8,NEIL2,CLEC2L,USP1,WIPF1,NSD2,MICU3,REEP1,SPIRE1,CADM2,PRDM10,C12orf4,FZD3,UBE3B,TTC7A,KLHDC1" MicroRNA hsa-miR-543:PITA hsa-miR-543:PITA_TOP PITA 8.19E-86 4.60E-82 4.18E-85 3.85E-84 175 575 "KCNH8,FMNL2,ADCY6,SLC12A5,PWWP2A,KLHL13,PCDH19,OSBPL8,FAM135A,ALS2,API5,CDC14B,CASK,MARCH3,DDX3Y,STX16,ATP2B1,NOL4,ADGRB3,BCL7A,JAZF1,BSN,WASF1,CALB1,CAMK2G,SPAG9,ARHGEF2,CDH2,DCLK1,MAGI1,DLGAP2,CHN1,CHN2,NRXN3,NMT2,DNAJB5,QKI,NIPBL,AKAP7,AKAP6,GAL3ST1,AHCTF1,MYRIP,SLC35F1,CLOCK,OSBPL3,CTH,TOX,MATR3,SIRPA,YTHDC1,ELMSAN1,MFAP3L,ZC3H11A,SMG7,SACS,SPOCK3,ARNT2,DLX1,NR1D2,CPEB2,GOLT1B,KLHL5,SH3GLB1,ELAVL2,PAN3,EN2,EPHB1,EPS8,EYA1,SEC24B,FGF12,MEX3B,PCYOX1,NPTN,ZNF512,MEGF11,CAB39,GATM,GGT7,PPARGC1A,TTBK1,TCERG1,SPIN1,GRB10,GRIK2,CIT,FAM222A,WIF1,BACH2,NEGR1,HSF2,SOWAHA,DOCK7,KCNA1,KCNMA1,IPO5,LIFR,LMO1,MEIS2,KITLG,AFDN,RSPO2,MYCN,NELL2,NKX2-2,CNOT4,NRCAM,PCSK1,PRTG,CDK14,SERPINI1,PLP1,SCHIP1,FAT3,NXPH1,PPP2R2C,CEP41,PROX1,CNNM2,PTCH1,PTPRB,PTPRD,PTPRE,PID1,FIGN,PBRM1,ZFHX4,ALG9,ATXN1,SCN2B,DOCK10,SLITRK3,BTBD3,CPEB4,SNAP25,LMBRD1,TEX2,RBM26,NPAS3,LMO3,LARP4,RGL1,SEPT3,PRRC2C,ATP11A,MTCL1,CAMTA1,TCF4,DMXL2,TRIM2,SYNE1,SIRT1,HHIP,HEY2,LRRC8A,CSMD1,TRPS1,TSC1,UBE3A,SLAIN1,SF1,PCDH20,ZIC1,ZIC2,REEP1,LAMP5,ZFAND5,WNK1,PRDM10,PAK5,KAT6A,RNF146,SOCS4,SENP7" MicroRNA hsa-miR-107:TargetScan hsa-miR-107 TargetScan 1.58E-85 8.86E-82 8.03E-85 7.39E-84 176 584 "ABCF1,ASIC1,GALNT13,RNF157,ADD1,AXIN2,OSBPL6,AK2,ALAD,OGT,ANK1,ANK3,CNTNAP1,LRRC4C,CASK,ARHGAP5,PDE8B,MARCH3,BCL2L2,DCAF5,CDK5R1,FUBP1,MTMR3,BTRC,CACNA2D1,CAMK2G,RUNX1T1,AIFM1,CDC27,CHRM1,NMT2,ARMC8,LETMD1,IFFO1,CLOCK,ENTPD4,AKAP12,CSNK1G3,APPL1,CTNND1,PPP6R2,PHF19,LONRF1,RIMS3,MAML1,GIT2,JAKMIP2,G3BP2,DLG4,DYNC1I1,NR1D2,FAM57B,RCAN1,EBF1,EDIL3,MBNL2,ABI2,EIF5,PLEKHA1,ELAVL3,RGS17,EN2,CEP85L,CORO2B,FOXG1,ANKFY1,CINP,NSG1,PHYHIPL,GABRB1,GABRG2,CAB39,DISC1,PCDH17,GK,RAB30,KIAA1958,GNAO1,FERMT2,CNDP1,GPR12,ADAP1,CECR2,KAT7,RASSF8,ARHGAP19,BACH2,HLF,HMGB1,HPSE2,AGFG1,KCNA2,KCND1,KCNH1,KCNN3,KIF5A,KIF5C,NAT8L,MAP4,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,MYCN,NF1,NFIA,NOS1,NOVA1,NOVA2,PAK3,PDE3A,PDE3B,PDE4D,ENPP2,CDK14,CAMKV,PIK3R1,PACSIN1,POU3F2,PPP2R5C,PRKAB2,PKIA,MAPK8,CNNM2,EML5,PPP2R3C,FAT4,ARID4A,RBBP6,PRRT2,RGS4,ALG9,GSTCD,RORB,FBXW7,ACER3,CLIP1,SALL1,ATXN1,ATXN7,SCN2A,SCN8A,COPZ1,SCAF8,KIF21A,ITSN1,PPM1E,CPEB3,FAM81A,LRRC55,MAPKBP1,FAM126B,PEG10,KIF1B,NPAS3,LHPP,PLCB1,MMS19,KAZN,SATB2,RPGRIP1L,GPRIN3,FRYL,DICER1,NR2C2,PRMT8,AMOT,BCL2L13,KCNK12,NAV2,GOPC,ADAMTSL3,PIANP,GAN,JPH3" MicroRNA hsa-miR-103a-3p:TargetScan hsa-miR-103a-3p TargetScan 1.58E-85 8.86E-82 8.03E-85 7.39E-84 176 584 "ABCF1,ASIC1,GALNT13,RNF157,ADD1,AXIN2,OSBPL6,AK2,ALAD,OGT,ANK1,ANK3,CNTNAP1,LRRC4C,CASK,ARHGAP5,PDE8B,MARCH3,BCL2L2,DCAF5,CDK5R1,FUBP1,MTMR3,BTRC,CACNA2D1,CAMK2G,RUNX1T1,AIFM1,CDC27,CHRM1,NMT2,ARMC8,LETMD1,IFFO1,CLOCK,ENTPD4,AKAP12,CSNK1G3,APPL1,CTNND1,PPP6R2,PHF19,LONRF1,RIMS3,MAML1,GIT2,JAKMIP2,G3BP2,DLG4,DYNC1I1,NR1D2,FAM57B,RCAN1,EBF1,EDIL3,MBNL2,ABI2,EIF5,PLEKHA1,ELAVL3,RGS17,EN2,CEP85L,CORO2B,FOXG1,ANKFY1,CINP,NSG1,PHYHIPL,GABRB1,GABRG2,CAB39,DISC1,PCDH17,GK,RAB30,KIAA1958,GNAO1,FERMT2,CNDP1,GPR12,ADAP1,CECR2,KAT7,RASSF8,ARHGAP19,BACH2,HLF,HMGB1,HPSE2,AGFG1,KCNA2,KCND1,KCNH1,KCNN3,KIF5A,KIF5C,NAT8L,MAP4,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,MYCN,NF1,NFIA,NOS1,NOVA1,NOVA2,PAK3,PDE3A,PDE3B,PDE4D,ENPP2,CDK14,CAMKV,PIK3R1,PACSIN1,POU3F2,PPP2R5C,PRKAB2,PKIA,MAPK8,CNNM2,EML5,PPP2R3C,FAT4,ARID4A,RBBP6,PRRT2,RGS4,ALG9,GSTCD,RORB,FBXW7,ACER3,CLIP1,SALL1,ATXN1,ATXN7,SCN2A,SCN8A,COPZ1,SCAF8,KIF21A,ITSN1,PPM1E,CPEB3,FAM81A,LRRC55,MAPKBP1,FAM126B,PEG10,KIF1B,NPAS3,LHPP,PLCB1,MMS19,KAZN,SATB2,RPGRIP1L,GPRIN3,FRYL,DICER1,NR2C2,PRMT8,AMOT,BCL2L13,KCNK12,NAV2,GOPC,ADAMTSL3,PIANP,GAN,JPH3" MicroRNA hsa-miR-1243:mirSVR_highEffct hsa-miR-1243:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.97E-85 1.11E-81 1.00E-84 9.25E-84 238 1068 "NBAT1,ARID1A,NDRG3,NDRG2,KIAA1211,KIDINS220,DPY19L2P4,SLC24A4,ZNF608,WDR35,HFM1,ADGRF5,C1QTNF3,ABCD2,AMPD3,ALS2,VAT1L,CADPS,MARCH3,IL33,CA8,CACNB2,PTBP2,CBR1,MTMR7,TMEM257,CDC42,CDO1,SRSF11,CHM,NRXN1,FAM19A5,DNAJB5,QKI,TMEM155,CNTN1,AKAP7,COL4A5,GAL3ST1,AHCTF1,FAM171B,CREM,HAPLN1,NCOR1,GDA,SNCAIP,ATRNL1,ERC2,PHF14,CTNND2,USP6NL,CCDC144A,CYBB,ARHGAP32,TCAF1,LIN54,PABPC5,BRINP1,DNAJC6,MYEF2,MAGI2,DDX46,G3BP2,KBTBD11,DMD,DTNA,FSD1L,EGFR,RGS17,TMEM35A,VPS13B,EXTL2,EYA1,ZIC4,CEP78,MED12L,OLFM1,WDR83,SMC2,UFM1,MSANTD4,NRG3,GABRA2,CHL1,GABRB3,GAD2,AHCYL1,B4GALNT1,PPARGC1A,DBF4,TOX3,STARD3,LUZP2,LNX1,GPD1,PRUNE2,LPAR4,GRIA2,GRIK4,NR3C1,ATE1,LINC01551,PSIP1,MIER3,ZNF546,DOCK7,IL6ST,ITGAM,KCNJ5,KCNMA1,KIF5A,STXBP5,TTYH2,NCOA7,SMAD9,MAT2A,MBNL1,PPM1L,AFDN,ZNF680,COL28A1,BCO1,MYO9A,NAP1L3,CCDC13,NEUROD1,NODAL,CNOT4,SLC11A2,NTRK2,GLIPR1L2,PCDH9,PDCD2,NLGN3,SEMA5B,ZNF655,FAM218A,A2ML1,CCSER2,HMGCLL1,PURG,PRIMPOL,PMP2,TRHDE,RC3H2,SLC36A4,PPP2R2C,SAMD9,VPS13C,SIDT1,GON4L,PTCH1,TMEM260,PTPRB,EML5,PTPRE,PTX3,PLEKHB2,OXR1,FEZF2,RADX,RET,SEC61A2,SLC25A36,NUDT11,ZFHX4,CCDC82,GSTCD,CCDC102B,RPE,RPS6KA2,LRRK2,RTKN,FAM182A,RMI1,SALL1,FNIP1,HKDC1,FBXO11,CCDC88A,ATF7IP,TET1,ZFP1,CXXC4,DMRTC1,RCOR3,SNCA,SNRPN,TNIK,SOX10,HECW1,ATP10B,SSTR1,SS18,RGL1,KLHL7,ZC3H4,PRRC2C,SYN2,SYT1,SYT4,ANKRD12,MTCL1,KLHL4,ZEB1,WDR7,PCDHB4,FRYL,CRB1,HHIP,TMEM9,TLR4,ERCC6L2,TMPO,BEX4,NPL,WBP2,SMUG1,SSBP2,FRRS1L,PITPNB,VSNL1,WIPF1,ZNF781,ZNF32,KCNT2,PLPPR5,PRDM8,ADAMTS9,GAL3ST3,NAV3,WNK3,NELFE,EPM2A,RGS7BP,UBE3B,SSPN,FRMD6" MicroRNA hsa-miR-3165:mirSVR_lowEffct hsa-miR-3165:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.98E-85 1.11E-81 1.01E-84 9.29E-84 254 1208 "SERPINA3,ABAT,DGCR6,KCNH8,ACTN1,ACTN2,SLC25A25,SLITRK1,PNMA8B,RNF150,BEND6,OLMALINC,SLC24A4,SNX32,SORCS2,OSBPL8,ALCAM,BCAR3,GOLGA7B,UNC79,AMPD2,AMPH,ANK3,SUGT1P4-STRA6LP-CCDC180,KCNAB2,ALS2,BCAS1,APP,MIER1,RGS20,ASTN1,TMEM108,CHID1,ZNF583,MTMR9,CARMIL3,BBS2,NRP2,BTRC,CA8,CACNB2,CACNB4,CALB1,CALB2,THSD7A,KALRN,HAP1,CAMK2A,SHISA7,P2RX6,L3MBTL4,LOC730101,CFL2,ZFYVE9,PPT2,QKI,COL9A2,ABI3BP,RCHY1,SLC35F1,CRMP1,TENM4,ATRNL1,CFAP61,CTNND1,CYBB,GAPVD1,HDAC4,EARS2,TM9SF4,AIF1L,PITPNC1,ZEB2,MFAP3L,HP1BP3,SV2B,SV2A,SGSM2,RABGAP1L,WDR20,CPEB2,MAMLD1,DNM1L,EBF1,EDNRA,HIPK3,FCF1,HEYL,EBI3,PLEKHA1,ING4,PAN3,COQ7,ABCA8,EFEMP1,DLC1,RACK1,ZMYND10,FDFT1,FER,GTF2IRD2,PRKAG2,FLYWCH1,CAMKK2,KHDRBS3,GALR1,ZNF559,DISC1,KIAA1841,NEU3,GCK,GJB1,TCERG1,STARD3,ZNF638,ZNF782,GPR22,DIDO1,GRIA4,PLCD4,GRM7,CIT,RNF165,LINC01551,FAM107A,ADAMTS6,MAEL,RASSF8,MAN1B1,BACH2,RBPJ,IL11RA,ITGAV,KCNK1,KLRC2,MAN2A2,AQP11,MATN3,MBD1,MBNL1,MIA2,MID1,ERICH3,JAKMIP3,MYO6,NHLH1,NODAL,NRCAM,NTRK2,NUCB2,CHAMP1,PDE2A,PFKFB2,NLGN3,SEMA5B,PLCB2,PLXNB3,PURG,POLR2F,PRKACB,MAPK8,GRAMD1C,SLC22A23,CNTLN,PTPRB,NKAIN1,CCDC40,SH3TC2,RASGRF2,HKR1,RDX,ERI2,PRIMA1,RNF220,RPRD1A,KLHDC8A,ROBO2,CCDC25,NEK11,EPHA10,UEVLD,PRR5L,ACER3,WLS,FAM192A,SCP2,SGK1,NTNG1,FBXO11,FNDC3A,BCAN,SYBU,CTXN2,NUBPL,EPN2,SLC6A1,SLCO1A2,SLIT1,CXXC4,SMARCD3,SMARCE1,RCOR3,ANKRD36,SNAP25,MBD5,TMCC1,RBM34,SOX10,ZSWIM8,CLUAP1,CAND2,KDM4C,PEG10,NFASC,SS18,ELOVL4,NSFL1C,KLHL7,NECAB1,FGD4,ADAMTS17,SYN1,SYN2,SLC37A2,PJA1,DDHD2,UNC5D,WWC1,TPCN2,SZT2,PCDHGA11,NAT16,HIF3A,DAAM2,CABIN1,TNS1,RASD2,ZNF346,ELP5,RUSC1,RFTN2,TTC3,CADM1,RPL7L1,MEAF6,ZNF28,PLPP4,REEP1,CSDE1,ADAMTS9,TMEM63C,NUP214,TTC7A,NETO1" MicroRNA hsa-miR-146b-5p:mirSVR_highEffct hsa-miR-146b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.47E-85 1.39E-81 1.26E-84 1.16E-83 236 1052 "KCNH8,CLK4,KIAA1211,ESYT2,ADRB2,DPY19L2P4,INTS2,RTL9,KIAA1324,LRRC7,SPOP,FAM135A,AMPH,CASK,ARRB1,CAPRIN2,NCOA1,NUMB,ATP2B1,B3GALT2,DCAF5,NRP2,BMPR1B,SYNJ2,JAZF1,GYG2,RAB29,LURAP1,KALRN,RUNX1T1,CLDN10,CCK,USP6,USP2,CDH10,DIS3L,CFL2,SYNPR,EPS15L1,ABCG2,TMEM155,ARMC8,COL4A5,ANKRD35,SLC25A27,COL9A1,BTF3L4,SLC4A8,ABI3BP,GDA,SEC24C,APPL1,PHF14,PUM1,CCDC144A,DOCK4,TOX,C8orf34,ZEB2,ZBTB24,HP1BP3,C2CD2L,SRGAP3,RAB39B,DMD,USP3,CDON,ACOT8,DTNA,ABCC5,EDNRB,FCF1,RASGRP1,FRY,YAF2,PHF20L1,GOLGA7,KCTD3,EIF4G2,PCOLCE2,TUBD1,MRPL37,SIRPB1,CLVS1,SH3YL1,SCML2,GORAB,SLC9B2,KIAA1109,AMOTL2,FHL1,MEX3B,RGPD5,STAMBP,CELF1,DACH2,CSPG5,MSANTD4,SARAF,FYB1,PHYHIPL,BRPF3,MTHFD2,MSTN,MALT1,RUNDC3A,COPS8,SPIN1,KDM2B,TDRKH,EML4,PCLO,STMN2,GRID1,CIT,MFSD2A,CELF3,HAS2,HMGCL,USP54,IGSF1,IL6ST,ZNF385B,LRRTM3,ITPKB,KCNJ16,KCNK2,STXBP5,INSYN2,HECTD2,MARK1,SYT9,LDLRAD3,SRSF12,MID1,MMP16,SESN3,ZNF92,ZC3H12B,NOVA1,CLDN11,PDGFRA,NLGN3,HMGCLL1,PURG,SCHIP1,POU3F2,MED1,MAPK10,DIRAS2,DCHS2,BCAS3,TMEM260,STK32A,PTPRE,PID1,USP47,ZNF493,RBBP6,SLC6A15,ERI2,RIT2,RIC8B,ZFHX4,ZNF532,CARF,PNMA8A,ROBO1,TMEM100,SNX22,MCMBP,ADAL,ZNF331,DGLUCY,MIR124-2HG,SH3BGR,ITSN1,SH3GL2,FERMT1,WDR47,RAB3GAP1,CCDC88A,DMRTC1,TTC17,RIMS1,USP33,PDZD2,PEG10,DBNDD2,TAB2,PBLD,CLASP2,COLGALT2,ZC4H2,ZSCAN29,SYNE2,SYT1,ANKRD28,ANKRD12,DDHD2,CAMSAP2,ADGRL3,KLHL4,RPGRIP1L,DOCK9,SLC19A3,ARL10,TJP1,DDHD1,ERCC6L2,HEY2,TPM1,RGMB,RUNDC3B,PPIL6,RFTN2,TTPA,ZKSCAN5,TUBB1,SLC35A4,DNAJC12,PLEKHH2,ZIC1,ZNF32,TRIM9,ZNF540,GPR158-AS1,ZNF138,ZNF142,PLPPR5,WNK1,CADM2,PLSCR4,SMIM8,PHTF2,FXR1" MicroRNA hsa-miR-380*:mirSVR_lowEffct hsa-miR-380*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.11E-85 1.75E-81 1.58E-84 1.46E-83 212 855 "RALGAPA1,ABAT,SYN3,CLK4,SYS1,GRAMD1B,PCDH19,HACE1,TXNDC16,SPARCL1,PCDH10,BBOX1,SUGT1P4-STRA6LP-CCDC180,ANXA7,UPRT,SHTN1,PPP4R4,TMEM108,SLC4A4,ATP1B3,ATP2B3,ADAM23,DNAJC27-AS1,SYNJ2,IL33,BTRC,PTBP2,VXN,BRSK2,RUNX1T1,PRC1,TMEM257,CDH8,NUMBL,ZFYVE9,TJP2,MAP4K4,IGLON5,AKAP6,HS3ST5,ZNF385A,SLC35F1,VCAN,CNTNAP2,PPP1R16B,PHF14,CTNND2,PUM1,DCAF4,GAPVD1,MATR3,TMEM170A,TOMM20,JAKMIP2,ZEB2,SV2B,SGSM2,NR1D2,DMTF1,DPP6,DTNA,DNAJB6,E2F5,PHF20L1,EIF5,CALCRL,VPS13B,GPHN,ADGRV1,RACK1,STRADA,KAT8,ZNF589,UBE2E3,SYNCRIP,COQ5,ATP2C1,STAG2,ZNF274,GAP43,DISC1,ATP8A2,ARFIP1,LYVE1,ZNF638,LUZP2,ADGRA3,GPD2,GRIA1,LINC00839,RNFT2,GYG1,HAS2,MAN1B1,HSPA1L,FAM95B1,SOWAHA,RBPJ,IGSF1,SCIN,LRRTM3,KCNMA1,KCNN2,MAN2A2,MAP4,ADAM22,MSR1,MYO7A,PABPC1L2A,HNRNPM,NDUFA5,NEUROD1,ALDH1L2,NOVA1,DNHD1,SETD4,CHAMP1,OPA1,CNTN3,PCDH9,PDGFRA,NALCN,HMGCLL1,PRIMPOL,RC3H2,ING3,EPB41L4B,DRAM2,PPP3CC,PRKCZ,GRAMD1C,HYDIN,GON4L,ANKHD1,UHRF1BP1,OCIAD1,PTPRE,USP47,FAT4,KHDRBS2,ERI2,RGS4,MRPS18A,RIC8B,ARMC5,ELP2,TMEM100,RPL15,LRRK2,WLS,RTKN,RYR3,SALL1,TNFRSF19,SLC30A10,SOX6,SUPT20H,SCG5,KIF21A,NTNG1,FNDC3A,DZIP1,WDR37,ABLIM3,SLC2A5,KANSL3,BTBD7,ATF7IP,SLN,GKAP1,KIF13A,TRERF1,SOX15,GLT8D1,SPTAN1,NFASC,TAB2,ATP10B,POGZ,ITPRID2,LARP4,PHLDB1,STX1A,C3orf70,CAMSAP2,UNC5D,ALG1,KLHL4,SATB2,TRIM2,CRB1,HHIP,SLC44A1,TIAM1,TIE1,TLL2,BHLHB9,TRO,PPIL6,TSN,TTC3,MEAF6,XPO1,ZBTB16,REEP1,AMZ1,DPYSL5,WNK1,EMSY,STOX2,LMAN2L,KAT6A" MicroRNA hsa-miR-128:mirSVR_highEffct hsa-miR-128:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.47E-85 1.95E-81 1.76E-84 1.62E-83 240 1088 "RALGAPA1,ADRB2,AK2,SMIM17,SUGT1P4-STRA6LP-CCDC180,APBA2,GPAM,TMEFF1,PDE8B,MARK4,ASPH,ALDH4A1,RNF182,DPY19L3,DOCK11,TTLL9,C5,PTBP2,CAMK2D,CAST,SPAG9,NFS1,LRRFIP1,MAGI1,CIART,COPB2,SRSF11,SOCS6,IGFBP7-AS1,TJP2,C4orf33,HECTD1,NIPBL,IGLON5,ARMC8,CABP1,LETMD1,RNF14,CSF1,VCAN,NCAN,SOCS5,ERC2,CFAP61,RIMS2,ECE2,BOC,GAPVD1,ARMCX4,MAGI2,SMG7,SV2B,SRGAP3,KBTBD11,DNM1,DMPK,HS3ST2,USP3,DMTF1,ARRDC4,DTNA,ABCC5,EDN3,EDNRA,YAF2,EBI3,EGR3,TNK2,EML1,MTSS1L,EPHB1,SRRM1,F3,ATP8A1,FCGR1A,FGF1,PRKAG2,SUCO,UBE2E3,ATP13A4,OGA,MEGF11,GABRB1,GAD1,GAD2,ARPP21,DISC1,GCNT2,GHR,RUNDC3A,GK,ZNF638,GPD2,CECR2,GRIA1,DIDO1,GRIK3,TMEM25,KAT7,MAP4K5,WIF1,HMGCL,TLX1,HSPA1L,SMAP1,HTR2A,MSL1,LIX1,IL6ST,CDH20,KCNK2,KCNMA1,CREG2,STXBP5,ARHGAP12,CLEC18A,MAP2,AQP11,MDM4,CD200,NAP1L2,NEK1,NF1,NFE2L2,NME4,NPY,NTRK3,TBC1D25,OPHN1,ZNF827,PAH,PCDH9,CDK18,PRTG,PDE3A,PDE4D,SLC10A4,GNG2,PFKFB4,OLA1,ZNF655,HMGCLL1,RASGEF1B,SLC26A11,DIRAS2,RELN,VPS13C,SLC22A23,DEF8,CNTLN,PTCH1,MTMR10,FAM66C,FAM184A,RBBP6,RDX,RET,REV3L,MRPS18A,SETD5,KLHDC8A,ALG9,ELP2,FAM192A,AMER2,CASC3,SFPQ,ITSN1,SH3GL3,PPM1E,NTNG1,R3HDM2,CNKSR2,WDR37,SLA,BTBD3,RADIL,CCDC88A,ELMO2,SLC22A4,RCOR3,RIMS1,SNAP25,SNRPN,UNC80,WDTC1,KIF21B,SP2,SP4,ENKUR,KDM4C,ZC3H13,NPAS3,SRPK2,CLASP2,TROVE2,POGZ,COLGALT2,SS18,NXT2,ELOVL4,ADHFE1,SEPT3,KLHL7,SYNE2,VPS13A,PLCB1,SYT1,TACR1,CAMTA1,MCF2L,PDLIM2,UNC5D,TCEA1,ZEB1,TPCN2,WASHC4,WDR7,FRYL,SIRT1,CRB1,TPM1,TTC3,FAM155A,OSBP2,BEST1,ZBTB14,PLPP4,WNK1,CA10,MAP3K12,MDH1B,NAV2,DOCK8,RTN4,CASC15,ZNF248,VANGL2,IFT88,NETO2" MicroRNA hsa-miR-492:mirSVR_lowEffct hsa-miR-492:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.47E-85 1.95E-81 1.76E-84 1.62E-83 240 1088 "EMILIN3,XKR4,ADD1,RNF150,OLMALINC,TAOK1,KIF6,LRFN1,CDC42BPA,PPFIA4,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,AMER3,CDK10,SEMA4G,PLA2G4C,LINC00173,MARK4,NCOA1,NUMB,SLC4A4,NOL4,BACH1,DCAF5,KSR1,ARHGEF7,RAB29,CA12,CACNA1D,DDR1,PTBP2,TRIM41,VXN,RUNX1T1,AIFM1,ENTPD6,ZBED1,CHGA,CASC2,CHRNB2,TPP1,DGCR9,DNAJB5,SRP14-AS1,SUMF2,BTF3L4,IGDCC3,SEC31B,CREM,ENTPD4,SH2B1,ANKRD44,SNCAIP,MICAL2,VCAN,CTH,CFAP61,INTS1,IST1,DAPK1,ELMO1,MFAP3L,HP1BP3,C2CD2L,DDX46,SV2B,RABGAP1L,DLX1,DNAH9,DOCK2,SLC12A6,DRP2,ECM2,KRBA2,ANKRD46,EGFR,EPB41,EPHB1,IGSF6,ZNF549,MRPL10,SIRPB1,CORO2B,ZNF589,FER,GTF2IRD2,FGF11,FGFR1,BAIAP2,FHL1,HPCAL4,FOXG1,FOXM1,NOP56,ZNF605,STAU2,GABRA1,ZNF274,ALDH1L1,ARFIP1,SESN1,AHDC1,GGT7,RND1,AIFM3,GNAS,LILRA1,LINC01089,TMEM179,MAN1B1,ARHGAP36,BACH2,EID2B,C2orf72,HES5,DIPK1A,SYTL4,ASPRV1,MAN2A2,CHIC1,MEIS1,MPP2,PTOV1,N6AMT1,SCG3,MYO6,RTL5,FXYD7,NNAT,VWA2,NOVA1,DNHD1,NPTX1,HCN1,DDR2,NUCB1,NUCB2,OCRL,OGDH,LOC100128398,CNTN3,PC,SLC10A4,SEMA5B,CAMKV,PURG,PRIMPOL,PNMA3,PMP2,PRRX1,SEPT4,FSD1,MED1,PPP1R1A,PPP3CB,GRAMD1C,PSMD13,ZSCAN32,C1orf109,ZSCAN2,NKAIN1,TTC13,MARCH1,CCDC40,GTDC1,UBR7,MRPS18A,RPRD1A,ZFHX4,ROBO2,SGSM1,EMID1,STX1B,DGLUCY,SBF1,HOGA1,SCN2B,ITSN1,FAM102A,SHC4,FNDC3A,ST6GAL1,ANKRD6,NUBPL,SLC1A3,SLC1A7,PPP4R3A,BTBD3,SLC6A1,SLC6A11,SLC8A3,ATF7IP,SORCS3,SNRPN,SCN3B,SOX1,KDM4C,IDI2-AS1,NKAIN2,ZSCAN29,RHBDL3,ARHGEF9,FNDC9,DNAJC9,MLST8,WWC1,VWA3A,SZT2,TMEM151B,USP32P1,CYB561A3,CRB1,TLL2,ZFP91,R3HDM1,TPM1,SMUG1,TRO,TTTY15,GORASP1,BCL2L13,TBC1D15,CLIP2,TRIM9,PLPP4,LYPD6,ZNF154,SPIRE1,LAMP5,SMARCAD1,EMSY,PRDM2,PARP6,PRDM10,NAV2,PHTF2,CERS6,TRAM2-AS1,ZNF248,SPATA13" MicroRNA hsa-miR-23b*:mirSVR_lowEffct hsa-miR-23b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.98E-85 2.23E-81 2.01E-84 1.85E-83 242 1106 "SYN3,ABHD6,SYS1,SLC25A25,ADD2,AXIN2,ADORA2A,C1QTNF1,LRRC7,SRPX,MARCH4,AMPD2,PPFIA4,CNIH2,SUGT1P4-STRA6LP-CCDC180,EPB41L5,VAT1L,CPNE5,AQP6,ZFYVE28,CCDC74A,ASTN1,TMEM108,SLC4A4,SLC2A11,CADM3,DPY19L3,ADGRB2,SEC11C,CFLAR,SCAPER,GYG2,RAB29,SPAG9,ZNF501,P2RX6,CBFA2T2,SEPT7,ZBED1,CACNA2D2,CFL2,C7orf61,RAB28,PLAA,COG1,MYL6B,DGCR9,SRP14-AS1,IGLON5,TOGARAM2,PNKD,HAPLN1,TRIM69,CSF1,ARHGEF10,SUSD5,VAC14-AS1,CNTNAP2,KIAA0040,CFAP61,TOX,TM9SF4,TBC1D5,INTS1,IST1,AIF1L,DNAL1,YTHDC1,JAKMIP2,C8orf34,POM121,SMG7,PLPPR4,SV2A,MTX3,DLX1,GRIN3A,HS3ST2,DYRK1A,ABCC5,OPTN,SUGP2,AASS,EPB41L1,SRARP,SIRPB1,EZH1,TUBB3,CEP78,TOMM40L,FGF1,OLFM1,FGF11,TMEM164,FOXM1,EVL,SEMA4D,FLYWCH1,COQ5,WDR83,ZCCHC17,POMT1,DOT1L,MEGF10,GALNT15,BRPF3,RAPGEF6,ALDH1L1,WASHC2A,GLS,TNRC6A,PCDH11X,OS9,ZNF782,GRIA1,GRIA2,GRIA4,GRM7,LINC01551,SOX21,RNFT2,HPS5,CPT1C,HSD17B1,ATCAY,EID2B,DOCK7,KIAA1755,KCNJ3,KCNJ10,KCNN2,KIF5A,L1CAM,CAMK2N2,MAN2A2,ZFYVE27,MARK1,MEIS1,XRRA1,CPNE9,RTL5,NF1,DNHD1,CLEC9A,NTRK2,OGG1,PAK3,BEST3,TMIE,A2ML1,KCTD15,JAKMIP1,STRN3,LRP12,MINDY2,PPP3CB,PKIA,PRKCB,PRKCZ,MAPK7,HYDIN,PTPRD,PTPRH,TMEM231,USP47,ENOX1,RFX2,UBR7,ZNF532,GSTCD,CCDC102B,EPHA10,SPIN3,MEG3,ABCA11P,HSD11B1L,ATAT1,TMEM156,S100B,ATXN2,TNFRSF19,IL17RB,ITSN1,HKDC1,AMBRA1,NLGN1,SLA,CCDC88A,CPEB4,SMARCE1,IFT122,PALLD,UNC80,WDTC1,ENKUR,EMC1,TEX2,ZNF423,SPART,SRPK2,COLGALT2,SSTR1,ZC4H2,ZSCAN29,NSFL1C,SYP,ATP11A,TBX15,CUX2,ZEB1,WDR7,NAT16,PCDHB9,PSD3,TNS2,FRYL,DICER1-AS1,GPR161,PRRT1,R3HDM1,C9orf85,DOK6,RGMB,RUSC1,TSC1,RFTN2,HSPBP1,EIF4ENIF1,OSBP2,BEST1,WIPF1,TRIM9,NDRG4,ZBTB38,URM1,CAB39L,TRIM16L,PARP11,MARCH8,KAT6A,ADAMTS10,LAS1L" MicroRNA hsa-miR-601:mirSVR_lowEffct hsa-miR-601:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.67E-85 2.62E-81 2.36E-84 2.17E-83 218 905 "ASIC2,SYS1,CSMD2,CSMD3,GALNT16,ADCY2,GRAMD1B,OLMALINC,GPR158,RTL9,USP35,ALCAM,GOLGA7B,TRMT9B,LGR5,MIER1,ZFYVE28,ARHGAP5,CADPS,CDK13,MARCH3,CAPRIN2,ZBTB10,CCDC181,ATP2B3,TTLL9,LINC00847,NRP2,DST,C1QC,CACNG1,CAMK2A,TRIM41,CAST,ARHGEF25,CD38,CFL2,COPB2,ASIC3,CHM,CHN2,TAOK2,KIAA1549L,AKAP6,TBPL1,ZNF385A,CDC42BPB,CLIP3,AATK,CST3,KIAA0040,PHF14,BOC,GAPVD1,DCAF8,LONRF1,TBC1D5,MATR3,INTS1,SIRPA,ARMCX2,DNAJC6,CNIH3,CEP170,SPOCK3,AK5,HS3ST2,DPH1,DNAJB6,AASDH,SNX29,FAM135B,HIPK3,FAM13A,TNK2,CALCRL,EMX2,EPB41,ANKRD13B,FGF11,FGR,FOXG1,MSANTD4,ZNF512,GABRA2,ZMYND11,B4GALNT1,NCKAP1,DISC1,GATM,NEU3,TCERG1,COPS8,GLS,PCDH11X,ZNF638,GNAO1,ADGRA3,GP1BB,LILRA2,GPR12,TMEM121B,GRM5,GRM7,ZBTB45,IRAK3,GABARAPL2,AGBL5,HNMT,SHISA6,GAREM2,INPP5B,KCND2,KCNJ3,KCNJ10,KCNJ16,NCOA7,CLEC18A,MARK3,NRBP2,MT3,SAMD14,NEXMIF,NTRK2,ZNF713,PAK3,PCDH9,PCSK2,PDE2A,PDE1B,PDGFRA,BEST3,PFKFB3,ST8SIA5,MTRF1L,PURG,ING3,CRLS1,PPP3CB,DIRAS2,KLK6,CNNM2,BCAS3,MDGA2,CNTLN,CCDC40,IQSEC3,DBX2,GAL3ST4,ZYG11B,TRIM68,FIGN,RFX5,ZDHHC4,SEC61A2,RNF220,ZFHX4,ZNF532,ALG9,PNMA8A,CCDC102B,SPIN3,SGSM1,ACER3,ATAT1,ZNF331,SEMA6D,ZFP30,SH3GL3,ARX,NTNG1,FBXO11,CTXN2,SLC1A3,WDR47,LRRC55,SLC9A5,INAVA,PDZD2,MYCBP2,ERC1,ZBTB43,NFASC,COLGALT2,ITPRID2,EPB41L3,TTBK2,PRRC2C,PLCB1,SYN1,C12orf76,TACR1,KLHL4,ANO4,TCEA1,DMXL2,CUX2,SYNE1,HIF3A,TNFRSF1B,C9orf85,PPIL6,TTC3,CLHC1,RPL7L1,EIF4ENIF1,SLAIN1,PITPNB,VLDLR,XPO1,XRCC4,GPR158-AS1,LRP8,SCG2,MDH1B,ITM2C,TMEM63C,ADAMTSL3" MicroRNA hsa-miR-379:mirSVR_lowEffct hsa-miR-379:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.24E-85 2.94E-81 2.65E-84 2.44E-83 221 930 "TTYH1,CLK4,ABHD6,C3orf14,CSMD3,KLHL32,TMCC3,BRAP,PLEKHH1,GRAMD1B,ADRB2,AGT,OSBPL1A,BBOX1,ZFAT,PHF12,PPFIA1,APAF1,APBB2,PPFIA3,TMEFF1,ASCL1,ASTN1,ALDH4A1,SLC4A4,ADGRB3,BBS2,KSR1,DST,SYNJ2,SCAPER,CALB2,CAST,SLC5A11,CD86,LRBA,SEPT7,SRSF11,NDST3,COG1,AKAP6,MAGED1,ABI3BP,AHCTF1,CNRIP1,CRY2,CRYM,CS,LRIG1,ATRNL1,PITPNM3,GREB1,DCAF4,RUBCN,GAPVD1,ARHGAP24,FRMPD4,DGKB,GIT2,DNAL1,ZEB2,ZBTB24,PLPPR4,G3BP2,WDR20,DLG3,EXOG,RAB39B,SLC29A4,DMTF1,DPYSL2,SLC25A18,DTNA,E2F5,SH3GLB1,PHF20L1,APH1A,EGR3,SORBS3,EPB41L2,EPHA5,TMEM74,DNAJC27,ARMCX1,CLVS1,SLC9B2,FGF1,PRKAG2,MEX3B,FOXF2,PDLIM5,ATP6V1H,MSANTD4,MEGF10,GABRA3,GAD1,C15orf41,ACSS1,GATM,IGSF5,MSTN,PPARGC1A,DHRS4,GLS,GPD1,GPD2,GPM6A,GRM3,GRM7,MFSD2A,FAM107A,HAS2,ZDHHC15,MSL1,LINC00667,OLFM3,KCNC1,KIF2A,STXBP5,HECTD2,ZNF667-AS1,MAOB,MAT2A,MEIS2,MYO7A,MYO9A,SLCO1C1,NFIA,HCN1,IGSF11,OGG1,KCNK10,PCSK5,PDE1C,PDE2A,PDGFRA,OLA1,GPSM2,PLEC,HMGCLL1,PNMA3,MAGEL2,POU3F2,PPP2R5C,PPP2R5E,MASP1,PIGG,PTHLH,RALGDS,HKR1,RET,FIGN,RFX4,DCUN1D2,RAVER2,ROBO1,KIAA0895L,ATP8B4,STK32B,HSD11B1L,ATXN2,SCN3A,LINC00461,CASC3,SFPQ,CTXN2,ST8SIA1,KANSL3,SHANK2,ELMO2,CXXC4,GKAP1,MAST1,RIMS1,MBD5,SNRPN,SON,SP2,KDM4C,RBM26,LMO3,SRPK2,ATP10B,ITPRID2,LARP4,SYN2,COBL,SYT4,TACC1,CAMTA1,EXOC7,PDLIM2,ACSL6,TCF4,TCF7L2,RPGRIP1L,PCDHB4,TNS2,PMS2CL,RIMBP2,TRPC1,HIRA,GORASP1,UGT8,PLEKHH2,WIPF1,KLC2,XPO1,ELFN1,ZBTB16,SMARCAD1,CA10,PRDM2,DNALI1,LRP8,CSDE1,DOCK8,PHTF2,JMJD1C,PIANP,FRMD6" MicroRNA hsa-miR-4314:mirSVR_highEffct hsa-miR-4314:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.55E-85 4.80E-81 4.32E-84 3.98E-83 232 1024 "ABCF1,KCNH8,ASIC1,FMNL2,BRAP,SORCS1,ADGRF5,LRRC7,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,APAF1,APLP1,TNRC6C,USP37,SEMA4G,PPP4R4,ARRB1,CAPRIN2,ASPH,ATP2B1,NOL4,ATP6V1G2,SEC11C,BCL2L2,CFLAR,SYNJ2,LINC00906,CACNB2,CAST,USP6,CDC27,CDH18,CHN2,CASC2,JAM2,NDST3,PPT2,CLTC,FBXO7,MAP4K4,ARHGEF6,ARMC8,ANKRD44,CLIP3,TRIM69,CS,CSF2RA,ATRNL1,APPL1,UBXN2A,GREB1,RUBCN,BOC,HDAC9,FGFR1OP2,GAPVD1,RIPOR2,DCAF8,TMEM170A,TOMM20,ARMCX4,HEPH,FBXL5,DMD,CDON,DTNA,EDN3,SGK2,PHF20L1,EGR3,STX2,SRRM1,CDKL3,VPS26C,SIRPB1,RPS6KC1,CEP78,TOMM40L,FER,FGF1,FGF11,FGFR1,FLT1,NOP56,PRELID3A,STAU2,GABRA2,HRASLS5,GABRB1,GABRG2,GALC,RAPGEF6,ARPP21,KIAA1841,IGSF5,GCK,WASHC2A,GLS,TOX3,GPD2,GRIK5,NR3C1,PRDM5,GRM5,ZNF496,PTPN5,COQ10A,LINC01551,AP4S1,GUCY1B1,HAS2,FRMD5,VSIG4,TLX1,SMAP1,MYLK2,USP54,LRRTM3,JAK1,KCND1,KCNMA1,IPO5,HECTD2,MAT2A,POC1B,MT1M,RTL5,NF1,NOS1,NRCAM,NTRK3,NUCB2,OPA1,PALM,PCSK1,PRTG,PIK3C2A,SMIM7,PURG,RC3H2,SCHIP1,SEPT4,MED1,PPP3CB,GRAMD1C,VPS13C,SLC22A23,APTX,WDR25,CNTLN,FAM120C,RAB5B,OXR1,GAL3ST4,RFX4,RGS12,ARHGEF10L,SEC61A2,RNF220,RNASEL,EXD2,RAVER2,KIRREL1,RPE,FBXW7,ATP8B4,ABCA11P,NCBP3,SAFB,LRRTM4,CASC3,KIF27,SH3BGR,ITSN1,FRMPD1,MYO18A,SHMT2,HKDC1,NLGN1,PAAF1,WDR47,SLC6A11,RAB3GAP1,CCDC88A,SPHKAP,SLC22A4,RCOR3,ZSWIM8,SP4,KIF1B,LHPP,TAB2,ELOVL4,SULF2,SYT11,FNDC9,SYN1,SYN2,DNMBP,VWA3A,WDR7,PCDHB7,C18orf54,ITGB3BP,ENHO,DDHD1,ERCC6L2,DAAM2,PRRT1,C9orf85,TRO,RUSC1,CA14,HEPACAM,PITPNB,CCDC14,VLDLR,BEST1,ZNF70,ZNF138,CELF4,PRTFDC1,DNALI1,HPS4,PCDH15,PARP11,GOPC,FAM13C,SMIM8,VANGL2,IFT88,AP3B2" MicroRNA hsa-miR-222*:mirSVR_highEffct hsa-miR-222*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-84 6.83E-81 6.13E-84 5.65E-83 216 893 "ACADM,SLC44A5,HACE1,TAOK1,ALCAM,BCAR3,ARHGAP20,UNC79,KIF6,CNIH2,PKP4,UPRT,API5,MIER1,NCOA1,NUMB,N4BP2L1,NOL4,CDK5R1,FUBP1,KALRN,CAMK2D,CAST,CBLN1,LRBA,DCLK1,LOC730101,CFL2,SRSF11,MS4A7,CLCN3,MAP4K4,CNR1,ARMC8,COL4A5,LETMD1,MFSD4A,HS3ST5,SEC31B,PREPL,RNF14,CSF1,OSBPL3,ATRNL1,CST3,FGFR1OP2,TCAF1,FRMPD4,CENPL,TMEM170A,GIT2,ARMCX2,ZBTB24,BLOC1S6,SMG7,G3BP2,DLG2,ABI1,ATN1,ECM2,KRBA2,AASDH,EBF1,EDN1,ANKRD46,FRY,STX2,CEP85L,ADGRV1,AMZ2,RACK1,CEP78,FCGR3A,TESK2,GORAB,MED12L,TMEM164,TMEM107,FAM49B,ZNF605,MPP6,OGA,PHYHIPL,MEGF11,GABRA1,ERAP1,MTHFD2,NEU3,GCNT2,PCDH17,TOX3,PCDH11X,ZNF638,GPD2,LPAR4,CNTRL,RAPGEF4,HNMT,SMAP1,MSL1,ZNF678,LRRTM3,GPR62,KCNJ5,KIF2A,KIF5A,KTN1,L1CAM,ZNF667-AS1,MEF2C,MEIS2,SRSF12,XRRA1,MOBP,CD200,ZNF680,ADAM22,MSR1,NRBP2,NCAM1,NDUFA5,NEK1,NOVA1,DNHD1,SLC11A2,GPR137C,SNTG1,ETFRF1,PDGFRA,GPR85,PFKFB2,CDK14,SERPINE2,FAM216A,SMIM7,ZNF426,TRHDE,PPM1B,PPP2R5E,RANBP3L,MDGA2,CNTLN,BDNF-AS,PTPRE,PTPRG,PTPRH,PTPRZ1,PTX3,MARCH1,ACSS3,RAP1GDS1,RASGRF1,KHDRBS2,GAL3ST4,RFX4,SLC25A36,ELP2,ARMH4,ZC3H14,MCMBP,PTGR2,MEG3,ABCA11P,TRAPPC13,ATXN7,LINC00461,TNFRSF19,TRA2B,SH3GL3,SLITRK3,ABLIM3,WDR47,SLC8A3,CCDC88A,SLC12A2,SORCS3,SNAP25,LMBRD1,SNRPN,UNC80,EMC1,LMO3,TAB2,NKAIN2,ELOVL4,ANKRD28,SYT4,FBXW11,TRIM2,WDR7,RALYL,AP4E1,TGFBR3,NACC2,SYNPO2,DCBLD1,ANKRD20A2,HIRA,AMOT,ZIC3,ATP6V0E2,FMN2,WNK1,EMSY,EVI5,KCNAB1,FAM13C,AMN1,PAK5,SMIM8,PHTF2,CASC15,ADAMTSL3,TIGD6,FXR1,DPF3" MicroRNA hsa-miR-105:PITA hsa-miR-105:PITA_TOP PITA 1.37E-84 7.72E-81 6.92E-84 6.37E-83 152 433 "RALGAPA1,SLITRK1,USP31,HECW2,DPP10,EP400,MAP4K3,GPAM,API5,ZBTB10,NCOA1,ATP2B1,CADM3,SCAPER,FOXK1,CAMK2G,CLDN10,LDB2,INA,CDH2,ZMYM4,CIART,CFL2,SRSF11,RAB3C,NRXN1,CNN3,CNR1,BTF3L4,CREB5,NCOR2,CSNK1G3,SOCS5,SLITRK5,HP1BP3,RHOBTB1,DLG2,ST8SIA3,RBM12,YAF2,MBNL2,EIF4G2,COPS4,PAN3,ERBB4,ETV1,EXTL2,ATP8A1,AMOTL2,SYNCRIP,NBEA,TACC2,CELF1,OGA,STAG2,GABRB3,CAB39,RND1,TCERG1,COPS8,SPIN1,TNRC6A,POLL,PCLO,GRIA2,GRIA4,GRID1,MAEL,KLF12,BACH2,MIER3,HLF,HMGB1,GABARAPL2,HNRNPK,HTR2A,IGF1,KLC1,MAP2,MARK1,LDLRAD3,MEF2C,MITF,MXI1,TCEAL5,NNAT,CNOT4,PCDH9,PCMT1,PDE4D,PDE1B,GPR85,GNG2,CDK14,PACSIN1,MED1,PPP3CA,PRKAB2,PKN2,MTMR10,PTPRE,PTPRG,RAB5B,OXR1,ZFHX4,ZNF532,MRAP2,CLIP1,ATXN1,SOX6,TRA2B,FNDC3A,FAM214B,CCDC88A,SLC12A2,CPEB4,CXXC4,SNAP25,FAIM2,FAM126B,SOX1,SOX11,SP4,TEX2,PEG10,NKAIN2,ELOVL4,ARHGEF9,SYT1,CAMTA1,TCF4,SATB2,WASHC4,DICER1,ZFPM2,TJP1,HEY2,RIMBP2,R3HDM1,TRPS1,TMEFF2,UBE3A,AMOT,FLRT2,ZIC3,CA10,PRDM8,PAK5,HNRNPA3,CERS6,SSPN,SENP7" MicroRNA hsa-miR-584:mirSVR_highEffct hsa-miR-584:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-84 7.97E-81 7.14E-84 6.58E-83 223 951 "DPF1,NBAT1,FMNL2,ADARB2,KIAA1211,GPR158,KLHL13,HACE1,KIAA1324,OSBPL6,LRRC7,SRPX,ANK1,ANK3,PPFIA1,ALS2,AQP4,TMEM263,CADPS,ATP1B3,ATP2B1,ZNF583,N4BP2L1,SEC11C,IL33,CACNA1D,CALB1,CALB2,CH25H,RUNX1T1,CD38,CDH8,SOCS6,CHN1,C4orf33,TMEM155,AKAP6,SLC4A7,MYRIP,ZNF521,AKAP12,HAPLN1,HINFP,NCOR1,MICAL2,VCAN,CFAP61,PUM1,USP6NL,GAPVD1,FRMPD4,DGKB,ARMCX4,DNAJC6,LYPD1,POM121,PLPPR4,SPOCK3,GRIN3A,USP3,NR1D2,DMTF1,FAM78B,E2F5,FCF1,PHF20L1,ELAVL2,EML1,CALCRL,DCTN4,EPHA5,RABEPK,NSRP1,FAM198B,TAOK3,CHST15,GTF2IRD2,MEX3B,ATP13A4,STAMBP,ATP6V1H,TBR1,ZNF512,HRASLS5,GALNT15,GABRG2,HBS1L,KIAA1841,DNER,ZNF276,SPIN1,GLI2,GLRB,MSL3,PCDH11X,MAP7D2,FERMT2,WDFY3-AS2,PSRC1,GRIA1,GRIK3,FAM19A2,HNMT,HSF2,LRRTM3,SLC35G1,KCND2,KCNK1,KCNK2,KCNN3,KIF2A,IPO5,MAP2,LYPLAL1,AQP11,MATN3,SYT9,MEIS2,KCTD6,SCAMP5,MITF,CD200,MSR1,ZNF92,MXI1,NAP1L1,NF1,NPTX1,PCDH9,PCMT1,PDGFRA,SLC10A4,OLA1,ZNF655,SNX10,PCDH18,EXOSC10,PRRX1,PACSIN1,CYBC1,PTHLH,PXK,PTPRB,TTC13,TUG1,CCDC40,SH3TC2,SUSD4,SLC6A15,REV3L,RFX3,RGS7,SLC25A36,CCDC82,SETD5,TMLHE,CARF,RORB,CCDC102B,RPE,FBXW7,ATP8B4,KCNIP3,ZNF354C,ZNF568,AMER2,SUPT20H,MAGI3,CNKSR2,CTXN2,NUBPL,CCDC88A,SHANK2,SLC12A2,SLC20A2,ANKRD36,INAVA,RIMS1,ZNF415,PALLD,UNC80,SON,HECW1,NPAS3,SPART,SRPK2,TAB2,POGZ,ITPRID2,SSTR2,EPB41L3,LARP4,GANAB,GSE1,SYT11,VPS13A,SYPL1,FBXW11,ZEB1,THBS4,ERCC6L2,C5orf64,TNR,C9orf85,PPIL6,TMEFF2,SLAIN1,TBC1D15,SLC13A3,ZBTB14,ZIC1,ZIC3,FSTL5,EML6,ANKS1B,PLPPR5,SIGLEC10,NAV2,EPM2A,RGS7BP,SMIM8,FBXO36,NUP214" MicroRNA hsa-miR-1322:mirSVR_highEffct hsa-miR-1322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.48E-84 8.32E-81 7.44E-84 6.86E-83 196 737 "NBAT1,XKR4,CSMD3,HECW2,NME5,WDR35,LRCH2,SUGT1P4-STRA6LP-CCDC180,MIER1,ARNTL,PLA2G4C,CDK13,MARK4,ZSCAN18,NCOA1,ATM,B3GALT2,N4BP2L1,PROM1,BMP7,NAE1,CACNA1G,CACNA1E,CACNA2D1,THSD7A,VSTM2A,CBR1,KRIT1,CDC42,CDH8,CDH18,LGI1,CHM,CNOT8,JAM2,ZFYVE9,NGEF,QKI,CNTN1,ABI3BP,CHD1L,FAM171B,CREM,CRHBP,AKAP12,HINFP,CSF1,SEC24C,GREB1,NRSN1,USP6NL,GAPVD1,TOX,SPOCK2,IP6K1,PITPNC1,CNIH3,DDX46,CHRDL1,GRIN3A,RAB39B,DNM1,HS3ST4,USP3,DTNA,DNAJB6,ATL1,GOLGA7,COPS4,GPHN,CDKL3,RRAGB,CLVS1,POLK,MEGF10,GALNT15,GABRB3,GALC,ARPP21,DISC1,NEU3,CBX1,LUZP2,GPD2,GPM6A,NUDT21,PLCD4,RFFL,GRIK2,GRM1,GRM8,TMEM25,IRAK3,BACH2,HTR2A,RBPJ,ITPKB,SLC35G1,OLFM3,KCNK1,KCNK2,KIF5A,C2orf80,MEIS1,POC1B,WDR49,ZNF680,OTOGL,NTRK2,PCSK5,PDE1A,PDE1C,BEST3,JAKMIP1,FTO,PLIN1,PURG,PMP2,EXOSC10,MINDY2,PKN2,EPDR1,CNTLN,PTHLH,PTK2,TMEM260,PTPN13,TMEM255A,RAP1GDS1,OXR1,RFX4,ATP8B4,KCNIP1,TRAPPC13,AP1AR,S100B,SATB1,CSRNP3,FAM19A1,SCN8A,CASC3,SH3BGR,NTNG1,MAGI3,SLA,CCDC88A,SMARCC2,SMARCE1,ANKRD36,RIMS1,CMTR2,SON,SP4,KDM4C,IDI2-AS1,KIF1B,NECAB1,PLCB1,SYPL1,DDHD2,CAMTA1,UNC5D,TCF7,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,TIMP4,TMEFF2,FAM155A,AMOT,SLAIN1,WIPF1,ZNF781,PCDH20,ZNF45,CADM2,PRTFDC1,RNF103,ADAMTS9,PLSCR4,HRASLS,CASC15,JMJD1C,ZNF248,RNF170,NHSL1,KLHDC1,IFT88,SLC4A10" MicroRNA hsa-miR-330-3p:TargetScan hsa-miR-330-3p TargetScan 1.48E-84 8.32E-81 7.44E-84 6.86E-83 196 737 "C3orf14,KLHL32,ADCYAP1R1,ADD2,ADD3,HECW2,KCTD16,ALAD,ARHGAP20,CARNS1,GPRASP2,CDC42BPA,APBB2,APC,GPAM,KIAA1614,ATP2B1,ATP2B2,MTMR9,CADM3,BACH1,NRP2,FUBP1,MTMR3,BSN,MYRF,LDLRAD4,BTRC,CA12,CALM1,CBFA2T2,C1orf52,CDH2,RAB3C,JAM2,NRXN3,IGLON5,PCYT1B,ACBD5,FAM171B,ARHGEF10,CSNK1G3,APPL1,NOS1AP,GAPVD1,FRMPD4,RIMS3,MAML1,IP6K1,CTIF,DNAL1,PITPNC1,JAKMIP2,ELMO1,CEP170,RABGAP1L,FAM107B,DLX1,DRP2,RCAN1,DYRK1A,EBF1,PHC2,HEYL,EFNA3,RBM12,EFNB3,MBNL2,ELAVL2,ING4,RCAN2,MTSS1L,ANKRD13B,EPS8,ERBB4,EFS,RCSD1,PTK2B,EFEMP1,PPP1R1B,MED12L,FGFR1,HPCAL4,AGAP2,DCTN2,CELF1,NSG1,NRG3,DKK3,GAB1,GABRA1,GABRA3,GABRB1,RAPGEF6,NCKAP1,ATP8A2,GBX2,GLYR1,GPR75,GLS,PRUNE2,GPM6A,GPR37,GRID1,GRM5,RNF165,IL1RAPL1,CELF3,RASSF8,HAS2,DDX19B,MIER3,HPSE2,HNRNPK,IL6R,KCNC2,KCNH1,KLHL23,KIF5C,L1CAM,ASPRV1,NAT8L,MARK1,MAT2A,PPM1L,AFF1,MRPL42,SCG3,RSPO2,NFIA,PCMT1,PDE3B,PDE1B,PFKFB3,CDIP1,LRP12,PRRX1,KANSL1,PRKAB2,MAPK10,DIRAS2,PROX1,OCIAD1,NKAIN1,RIC8B,LGI2,RAVER2,RORB,MCMBP,RIMKLA,KCNIP2,RXRA,CCDC112,S100B,ATXN7,HSPA4L,PPP1R9A,PPM1E,FNDC3A,NAPB,EPC1,COA1,SCN3B,KIF1B,GSE1,KLHL7,ATP11A,ACSL6,PCDHB15,PSD3,NSD1,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CBX5,ASXL3,BHLHB9,AMOT,FRRS1L,BCL2L13,MICU3,REEP1,DPYSL5,PRTFDC1,LRP8,PRDM8,ITM2C,PARP11,FZD3,JPH3" MicroRNA hsa-miR-222:mirSVR_highEffct hsa-miR-222:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.49E-84 8.38E-81 7.49E-84 6.90E-83 207 822 "RALGAPA1,ACADM,ARID1A,CSMD3,KLHL32,AXIN2,ERMN,LRFN2,WDR35,SPARCL1,PCDH10,PITPNM2,PPFIA1,PARG,APAF1,ASPA,CAPRIN2,ASPH,ATP1B3,ATP2B3,DPY19L3,BCHE,NAE1,CA8,CACNB4,DIRAS1,KRIT1,INA,MAGI1,CLGN,NDST3,KMT2C,C4orf33,QKI,NIPBL,CNR1,AKAP5,SLC4A7,CREM,GDA,RGS6,SEC24C,KIAA0040,USP6NL,KATNAL2,GAPVD1,TOX,ZFYVE16,KIAA0586,SPATA2,DNAJC6,ZEB2,MYEF2,SPOCK3,PDCD6IP,ARRDC4,DYRK1A,ABCC9,FCF1,EMX2,ABCA8,SEC24B,SUCO,SMC2,GABRA1,GABRG2,GALC,KIAA1841,MYOZ2,NEU3,SULT1C4,GDF9,PPARGC1A,BRD8,GLS,LUZP2,FERMT2,GPD2,GPM6A,GRIA4,ZBTB49,ADAMTS6,MAP4K5,TMEM179,MIER3,HNMT,SHISA6,ZNF181,LRRCC1,PLD5,BRINP3,INSM1,KCNA1,CLVS2,KCNK2,KIF5C,KIT,KLC1,STMN1,HECTD2,NCOA7,MARK1,MAT2A,MATN2,MEIS1,ADAM22,NAP1L2,NAP1L3,NEFH,NEK1,NOVA1,GPR88,CLDN11,CDK18,PDE4B,PFKFB2,A2ML1,RETREG1,PDZRN4,MAGEL2,NXPH1,MED1,CRLS1,PPP2R5E,PPP3CB,MAPK10,VPS13C,ANKHD1,PLPPR1,ZNF615,CEP97,KHDRBS2,RDX,ZYG11B,ERI2,RFX3,RGS4,RIT2,SEC61A2,SLC25A36,CARF,RORB,MRAP2,BAALC,SPIN3,MCMBP,SAFB,IL17RB,ZFP30,FERMT1,KIF16B,CPEB3,FBXO11,FNDC3A,SYBU,PPP4R3A,WDR47,CCDC88A,SHANK2,CPEB4,SNCA,TMCC1,SON,SOX10,ZC3H13,SPART,C11orf87,CLASP2,POGZ,ZNF302,NXT2,ADHFE1,DDHD2,CAMTA1,FAM208A,UNC5D,AGTPBP1,TCEA1,ZFP90,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CYB561A3,ZFPM2,ERCC6L2,TP53BP2,TRPC3,TRPS1,FNDC5,CADM1,TRIM9,EML6,PRDM2,TUBA1A,SEMA3B,NAV3,SLC17A6,PLSCR4,PAK5,MSRB3,AP3B2,SLC4A10" MicroRNA hsa-miR-323b-5p:mirSVR_lowEffct hsa-miR-323b-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.08E-84 1.17E-80 1.04E-83 9.60E-83 240 1097 "ABAT,GALNT16,ADCY6,ADD2,KIAA1211,KIDINS220,HECW2,KLHL13,CC2D2A,TRMT9B,FGD2,LGR5,AQP4,AQP6,CADPS,CDK13,CAPRIN2,ATP6V0A1,FGF17,ZNF599,CACNB4,CACNG1,LURAP1,HIP1R,MAP7,PRC1,CCKBR,CDH8,ARHGAP33,LGI1,LARGE1,MAGI1,NUMBL,CHM,B4GALT6,ZBED5,RAB28,NRXN3,TJP2,AKAP6,LETMD1,SMARCAL1,CNRIP1,CLOCK,CRMP1,NCAN,SOCS5,PDE4DIP,CTNND2,DOCK4,JAKMIP2,ZEB2,MFAP3L,POM121,RHOBTB1,SACS,SV2B,MTX3,CCDC3,CHRDL1,DLG2,GRIN3A,DNM1,DMPK,DNM2,DOCK2,ECM2,FAM135B,EDNRA,KLHL5,KMT5B,SORBS3,RGS17,PAN3,ENO2,MRPL37,CDKL3,ECSIT,NSRP1,RACK1,ST3GAL6,SEC24B,MEX3B,CAP2,IP6K2,CELF1,STAU2,ABLIM2,DKK3,GABRB3,BRPF3,IQGAP2,ERAP1,WASHC2A,LYVE1,BRD8,RND1,TCERG1,MSL3,PCDH11X,ZNF638,GPD2,PCLO,GRIA1,PLCD4,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,LINGO1,PSIP1,RNFT2,HAS2,PADI2,SCIN,IL11RA,BRINP3,KCNC1,KCNJ9,KCNK2,LINC00634,A1BG-AS1,KLC1,IPO5,STXBP5,STMN1,MAN2A2,AQP11,MATN3,MBD1,CHIC1,LDLRAD3,KCTD6,MMP16,LAYN,MYO7A,NCAM1,NME4,OCRL,GPR88,LOC100128398,P2RX7,GLIPR1L2,PALM,PCDH8,PCDH9,PCSK5,PDE4A,PDYN,PFKFB3,SLC25A23,SMIM7,PURG,PMP2,STRN3,RETREG2,PPP2R5E,CEP41,PRKCZ,DIRAS2,BDNF-AS,FAM120C,TMEM231,ZNF844,ARID4A,RBBP6,RNH1,RAVER2,CCDC25,RORB,FBXW7,PRR5L,PTGR2,PAQR6,KCNIP1,MIR124-2HG,LRRTM4,SUPT20H,PPM1E,KIF16B,FHOD3,NUBPL,WDR37,ZNF365,SLC6A7,SLC6A8,SHANK2,SORCS3,ANKRD36,KDM4B,DOP1A,SON,PDZD2,MYT1L,KIF1B,NFASC,LHPP,COLGALT2,NEK4,DIP2A,SEPT3,SYN2,MLST8,UNC5D,TBCEL,TBX15,CUX2,PUM2,TNS2,CRB1,ITGB3BP,TMOD1,TMPO,PRRT1,ZNF346,PDSS1,TRO,TRPC3,TRPS1,DCBLD1,TTC3,UBE3A,UGT8,SLAIN1,MGAT5B,VSNL1,PCDH20,ZNF23,EML6,CADM2,PRDM2,PRDM10,NAV3,PARP11,C12orf4,DOCK8,FBXO36,LAS1L" MicroRNA hsa-miR-891b:mirSVR_highEffct hsa-miR-891b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.82E-84 1.58E-80 1.41E-83 1.30E-82 218 913 "ACADM,FMNL2,SLC12A5,PWWP2A,SLC24A4,GPR158,OSBPL1A,WDR35,HFM1,FAM135A,ANK2,CCDC146,MAP4K3,PPFIA1,GPAM,APOC2,BCAS1,API5,NUMB,ATP2B3,DPY19L3,SEC11C,SYNJ1,MTMR2,IL33,CANX,VXN,ISPD,CLDN10,LDB2,KRIT1,CDC42,TIGD7,DIS3L,SRSF11,SYNPR,NRXN3,ZFYVE9,TJP2,ABCG2,TMEM155,AKAP6,BTF3L4,SLC4A7,CPS1,CREM,TRIM69,OSBPL3,PDE4DIP,PHF14,ARHGEF4,NRSN1,CCDC144A,DOCK4,HDAC9,ARHGAP32,TOX,LONRF1,PITPNC1,C8orf34,GSDME,DYNC1I1,ARRDC4,EDN1,SEMA3D,SH3GLB1,ABI2,TMEM35A,EPHA5,EPS8,CD320,FABP7,GORAB,SUCO,IP6K2,FOXO3,FOLH1,SMC2,UFM1,PDLIM5,ATP6V1H,AP4B1,DKK3,GABRA3,GABRB1,GAD1,NEK6,MYOZ2,GCNT2,COPS8,TNRC6A,CBX1,GNAS,NUDT21,EML4,PCLO,RAPGEF4,FAM19A2,RASSF8,ZHX1,FRMD5,MIER3,HMGB1,HNMT,SMAP1,C5orf24,DIPK1A,KCNJ3,KCNJ10,KCNJ16,KIF5C,KLRC2,TTYH2,LIG4,LYPLAL1,MOG,MRPL42,ADAM22,NELL1,NEK1,NF1,PDGFRA,ENPP2,GPR85,PIK3R1,SMIM7,PSAT1,NXPH1,DRAM2,PPP2R5E,PPP3CB,GRAMD1C,PRPSAP2,APTX,SYTL2,SIDT1,SNRK,MDGA2,QRICH1,ANKHD1,TMEM260,PTPRD,QDPR,FAT4,RAP1GDS1,GTDC1,FIGN,RFX4,RPE65,FBXW7,SPIN3,ZC3H14,ABCA11P,SOX8,CCDC112,ELMOD1,SUPT20H,PPM1E,NTNG1,CHD9,NLGN1,ZNF365,RUFY2,SLC8A2,CCDC88A,SMARCE1,MYT1L,FNBP1,KDM3A,NMNAT2,KDM4C,SS18,ELOVL4,SEPT8,SYT11,SYNE2,VPS13A,SYPL1,COBL,CAMSAP2,ANO4,TCF4,TCF7L2,PCDHGA4,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,AKTIP,FBXL16,ERCC6L2,TMOD1,KAT6B,TPM1,SSBP2,TUBB1,FAM155A,FLRT2,PLEKHH2,VLDLR,P2RY12,WRN,XPO1,ZIC3,ZFAND5,HPS4,TRIM16L,WNK3,PLSCR4,AMN1,CERS6,FXR1,FRMD6" MicroRNA hsa-miR-4291:mirSVR_highEffct hsa-miR-4291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.52E-84 2.54E-80 2.26E-83 2.09E-82 225 973 "ABCF1,KCNH8,ABR,CLK4,NCKAP5,ARID1A,NDRG3,SLITRK1,CDC7,PWWP2A,ADORA3,TAOK1,OGT,ANK3,UPRT,ALS2,TNRC6C,API5,SHTN1,SLC4A4,ATP2A2,DOCK11,BCL2L2,CFLAR,ST3GAL5,IL33,CACNA1A,CACNB2,CALM1,CAMK2D,CBS,MTMR7,EVI5L,LOC730101,SRSF11,CASC2,NRXN3,PLAA,C4orf33,ARMC8,HS3ST5,ZNF385A,FAM171B,AKAP12,LRRC3B,CSNK1G3,VCAN,RUBCN,DOCK4,RIPOR2,MATR3,SPOCK2,ARMCX4,ZEB2,GSDME,RHOBTB1,SMG7,WDR20,DNM1,HS3ST4,USP3,DPP6,GOLT1B,SEMA3D,FRY,APH1A,SRRM1,MRPL10,RCSD1,EYA1,F8,STRADA,FER,GTF2IRD2,PRKAG2,RGPD5,TMEM107,SPECC1,TRIM16,NPTN,CELF1,AP4B1,STAG2,GABRA2,AHCYL1,ARPP21,WASF3,TUBA8,SULT1C4,GPR162,PCDH17,GGT7,PPARGC1A,LYVE1,GLS,GLUL,ZNF638,KCNMB4,GPD1,GPM6B,CCDC184,GRIA2,RFFL,NR3C1,GRM7,FAM19A2,PSIP1,GYG1,ARHGAP36,MIER3,VSIG4,GAREM2,KNDC1,PLD5,IL6R,NME9,KCNC2,KCNJ11,KLC1,MAP4,MBD1,MBNL1,MDM4,LRP1B,MTTP,NF1,HCN1,SNTG1,PAK3,CNTN3,PCMT1,PDE3B,ABCB1,NOMO2,HMGCLL1,LRP12,SEPT4,HYDIN,RELN,SIDT1,PTHLH,PTH1R,PTPRD,PTPRG,RAB5B,ATG16L1,FAT4,RBBP6,BSDC1,TRIM68,FIGN,SEC61A2,RIC8B,LGI2,CCDC82,CNTNAP3,ATAT1,KCNIP1,RYR3,NCBP3,SCN2A,PRCD,SCP2,TRA2B,KIF21A,CHD9,NLGN1,ST3GAL3,SEC31A,SLC1A3,EPN2,DHX30,RAB3GAP1,SLC12A2,CPEB4,SMARCE1,SNCB,SNCA,MBD5,SNRPN,RBM34,MYT1L,KIF21B,TAB2,CLASP2,ELOVL4,SYT1,ANKRD28,MMS19,ATP11A,MTCL1,MCF2L,KIAA1107,DMXL2,SLC19A3,TGFBR3,TIAM1,DDHD1,ERCC6L2,HEY2,TMPO,RIMBP2,PRMT8,KCNE5,TSC1,CLHC1,CADM1,UCHL1,UGT8,PLEKHH2,MEAF6,P2RY12,WNT7A,PCDH20,ZNF24,SMARCAD1,DHX33,LRP8,PRDM10,TRIM16L,MVB12B,CASC15,TIGD6,NETO1,FAM198A" MicroRNA "GCACTTT,MIR-20B:MSigDB" "GCACTTT,MIR-20B:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-519D:MSigDB" "GCACTTT,MIR-519D:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-20A:MSigDB" "GCACTTT,MIR-20A:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-17-5P:MSigDB" "GCACTTT,MIR-17-5P:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-106A:MSigDB" "GCACTTT,MIR-106A:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA "GCACTTT,MIR-106B:MSigDB" "GCACTTT,MIR-106B:MSigDB" MSigDB 7.28E-84 4.09E-80 3.63E-83 3.34E-82 170 555 "SLC24A4,ANK2,APBB2,APP,SEMA4G,MARK4,RASL11B,ATP1A2,ATP2B2,BCL2L2,NRP2,MTMR3,JAZF1,NIPA1,KALRN,MAP7,USP6,DLGAP2,CFL2,SOCS6,TAOK2,KMT2C,ZFYVE9,QKI,PCYT1B,SLC4A7,AHCTF1,CLOCK,C2CD2,CREB5,CRY2,LRIG1,ARHGEF10,PPP6R2,DCAF8,HDAC4,KIAA0513,RASSF2,IP6K1,PLEKHM1,MFAP3L,FBXL5,SACS,SRGAP3,USP3,DNM2,DMTF1,DPYSL2,DNAJB6,DYRK1A,E2F5,KMT5B,EIF4G2,EPHA5,ETV1,DNAJC27,EZH1,F3,WAC,ACSL4,SCML2,MED12L,SUCO,FLT1,ANKFY1,NBEA,ST6GALNAC3,OGA,GAB1,RAB30,TNRC6A,RAPGEF4,GRM7,HAS2,KLF12,HLF,SCRT2,OLFM3,KCNJ10,KCNMA1,KCNQ2,KIF5A,CAMK2N2,ARHGAP12,MYCN,NBL1,NHLH1,CNOT4,OCRL,PDGFRA,PIK3R1,CCSER2,PKD1,XRN1,PRRX1,RETREG2,PPARA,PPP3CA,PKIA,MAPK4,MAPK9,PSD,SLC22A23,PTHLH,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ARID4A,ZNF532,ATXN1,FAM102A,CHD9,FNDC3A,SLITRK3,SYBU,WDR37,SLC1A2,SLC6A9,YPEL4,BTBD7,TET1,TMCC1,MYT1L,NPAS3,LMO3,CAMTA2,ITPRID2,SMOC1,RGL1,DIP2A,PLCB1,ANKRD28,CAMTA1,TAL1,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,USP32P2,DPYSL5,SLC30A3,CA10,MAP3K12,EMSY,RGMA,SLC17A7,WNK3,FAM13C,MARCH8,PAK5,PHTF2,CERS6,FRMD6,NETO2,ST8SIA2,GAN" MicroRNA hsa-miR-548d-3p:PITA hsa-miR-548d-3p:PITA_TOP PITA 8.43E-84 4.74E-80 4.20E-83 3.86E-82 193 721 "KCNH8,ASIC2,ARID1A,FMNL2,AXIN2,SORCS1,SNX30,GPR158,MARCH4,UNC79,PDZD4,PITPNM2,AMPH,CDC42BPA,APC,ALS2,USP37,SEMA4G,TMEM263,ZBTB10,ATP1A1,STX16,RNF182,CDK5R1,BTRC,SYT6,BRSK2,RUNX1T1,CDH2,CFL2,FOXN3,KMT2C,DLGAP3,NRXN3,NRXN1,COL4A5,CDC42BPB,CSNK1G3,SOCS5,DCAF8,TOX,PHF19,KCTD8,MYEF2,SMG7,SNAP91,MTX3,FAM107B,DLG4,GRIN3A,DMD,CPEB2,DMTF1,DPYSL2,ABI1,DYRK1A,RBM12,YAF2,KMT5B,EIF4G2,ELAVL2,ELAVL3,PAN3,EIF1,EPB41,RCAN2,ACSL4,SUCO,EVL,NBEA,CAB39,IQGAP2,SRCAP,ARFIP1,PCDH17,TCERG1,SPIN1,TNRC6A,PRRC2B,GRIA2,GRIA4,GRIK2,IL1RAPL1,PSIP1,MAP4K5,PACSIN2,FRMD3,BACH2,HLF,NEGR1,SMAP1,RBPJ,LRRTM3,KCNA1,IPO5,KTN1,MARK1,MITF,MSI1,ZC3H12B,NEK1,NFIX,HCN1,NUMA1,GPR88,PCDH9,PCMT1,GPR85,CDK14,NLGN3,PURG,STRN3,PRRX1,EPB41L4B,MED1,PPP3CA,KANSL1,SNRK,PTPRD,FAM120C,PTPRZ1,NKAIN1,PID1,RAP1GDS1,ARID4A,BSDC1,PBRM1,ZNF532,CARF,ZC3H14,RIMKLA,LRRK2,RTN1,SALL1,SEMA6D,SCN3A,ELMOD1,TRA2B,SGK1,CPEB3,DOCK10,CHD9,NLGN1,ST8SIA1,BTBD3,SLC6A1,CCDC88A,CPEB4,TMCC1,MYT1L,ZCCHC24,TEX2,CDK19,POGZ,COLGALT2,LARP4,ERBIN,GSE1,NSFL1C,FAM168A,PLCB1,ANKRD28,ATP11A,CAMTA1,CAMSAP2,UNC5D,CNTN2,TBL1X,DMXL2,RPGRIP1L,DOCK9,RALYL,PSD3,AHCYL2,R3HDM1,RBFOX2,TSC1,UBE2H,UBE3A,USP1,VAV2,MEAF6,PCDH20,ZFAND5,CADM2,RGMA,CSDE1,WNK3,PARP11,PDSS2,RGS7BP,KAT6A,HNRNPA3" MicroRNA hsa-miR-877*:mirSVR_highEffct hsa-miR-877*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.48E-84 5.32E-80 4.71E-83 4.34E-82 239 1096 "CLK4,CCDC85A,BRAP,SLC12A5,PTCHD1,KIDINS220,GPR158,TXNDC16,ZNF578,ADGRF5,ANK1,ANK3,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ALS2,MARCH3,CAPRIN2,FGF17,PROM1,SYNJ1,ARHGEF7,CASTOR3,CACNA1E,KALRN,PTBP2,VSTM2A,CAST,PRC1,METTL6,CCNT1,CBFA2T2,CDH18,CASC2,JAM2,SLC22A6,NRXN3,IGFBP7-AS1,CLCN3,NRXN2,MYL6B,NMT2,CNGA3,FAM149A,IGDCC3,HS3ST5,CHD1L,ENTPD4,GDA,UBXN2A,CFAP61,TCAF1,FRMPD4,IP6K1,GIT2,ZEB2,RUSC2,TMEM130,BLOC1S6,ZC3H11A,DDX46,RHOBTB1,SMG7,DMTF1,FAM135B,HIPK3,FRY,YAF2,ABI2,ELAVL3,ELAVL4,BSCL2,ETV1,PIPOX,EXTL2,EZH1,SCML2,DLC1,TOMM40L,ZSCAN30,TESK2,FGFR3,POLK,SUCO,SEMA4D,NELFCD,WDR83,APOPT1,PDLIM5,ZNF605,PNMA2,DOT1L,STAG2,MEGF11,TRAF3IP2,ARPP21,DISC1,IGSF5,GCNT2,ARFIP1,GJB1,BRD8,PCDH11X,STARD3,ZNF638,WDFY3-AS2,GPD2,PRLHR,STMN2,GRIA1,GRIA2,GRIK2,SPACA9,CIT,LINC00839,CLASRP,FAM107A,ADAMTS6,GUCY1B1,CELF3,HMGB1,USP51,MSL1,FAM95B1,KCNA4,CDH20,KCNJ3,KCNK2,KCNN2,CYP27C1,LIG4,LIMS1,LSS,PIK3AP1,LOC100128239,MAT2A,SYT9,MEIS1,MEIS2,AFDN,MMP16,MOG,COL28A1,BCO1,MXI1,BEX5,NELL1,NEUROD2,NODAL,NOVA1,DNHD1,NUCB2,PAK3,PCDH9,PDGFRA,GNG2,PFKFB3,CDK14,ABCB1,CAMKV,TMIE,FAM216A,RC3H2,POLR2F,CCDC144B,PPP2R5E,CEP41,QRICH1,BDNF-AS,PTK2,PXK,TMEM260,PTPRG,RALGDS,MORC4,RNASEL,SETD5,CARF,CCDC102B,NEK11,NCBP3,LRRTM4,SHC4,SLA,SLC1A3,RUFY2,FAM214B,ZNF430,YPEL4,RAB3GAP1,SPHKAP,ZKSCAN3,RCOR3,ANKRD36,SNCA,UNC80,MYT1L,KDM4C,PEG10,DBNDD2,RBM26,SS18,ZSCAN29,ADHFE1,FAM208A,ADGRL3,TCF7L2,ZEB1,WDR7,RNF216P1,TGFBR3,TNS1,RBFOX2,CDK20,TPM2,ZNF384,METTL3,TRPC3,RFTN2,TTC3,FLRT2,VLDLR,WIPF1,RICTOR,ZIC1,LYPD6,UPF3A,PMEPA1,PRDM2,LINC02210,PCDH15,NAV3,FIP1L1,WNK3,MRPL47,PAK5,ADAMTSL3,DPF3,SLC4A10" MicroRNA hsa-miR-200b*:mirSVR_highEffct hsa-miR-200b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-83 5.99E-80 5.30E-83 4.88E-82 222 952 "SDE2,XKR4,NDRG3,BRAP,KIDINS220,NLGN4X,KLHL13,KCTD16,RTL9,NME5,ADGRF5,LRRC7,OGT,MAP4K3,CDK13,ASTN1,SLC2A11,BMPR1B,KALRN,CAST,CCK,LGI1,ZBED5,CNOT8,KMT2C,TPP1,QKI,CNR1,BTF3L4,RCHY1,SLC35F1,FAM171B,HAPLN1,SEC24C,ATRNL1,IPCEF1,SLITRK5,PITPNM3,ERC2,PHF14,CTH,NRSN1,EDRF1,TCAF1,ZFYVE16,ARMCX4,PITPNC1,C8orf34,ZEB2,TIAM2,DDX46,PLPPR4,DPP6,ABI1,PDCD6IP,DYRK1A,ABCC9,E2F6,EDNRA,FRY,FAM13A,EPHA5,GPHN,STX2,TMEM74,MRPL10,DNAJC27,F5,CLVS1,DLC1,MED12L,FGF13,FGFR3,CAP2,UFM1,ERGIC3,NSG2,ST6GALNAC3,STAG2,GABRA2,CHL1,BRPF3,ARPP21,DISC1,IGSF5,SULT1C4,MSTN,ARFIP1,COPS8,GLS,GLUL,KDM2B,INSM2,PRUNE2,ATP2B1-AS1,GRIA4,C1orf94,ZHX1,MIER3,HMGB1,SHISA6,EID2B,RBPJ,LRRTM3,ITGAV,KCNA4,KCND2,KCNJ16,CREG2,KLRC2,STMN1,VWA5A,PIK3AP1,MAP4,MBD1,MBNL1,MEIS2,POC1B,MOBP,ZNF680,MSR1,ZNF92,NCF2,NEK1,NOVA1,SLC11A2,SMIM11A,HCN1,NTRK2,PDE3A,GPR85,GNG2,NLGN3,SERPINI1,PIK3C2A,ZNF655,ST8SIA5,ING3,TNPO2,NXPH1,POLR2F,CRLS1,PRKAB2,EPDR1,TMEM260,ZSCAN32,PEX2,ZNF493,SLC25A36,NUDT11,CARF,GSTCD,PCMTD2,CCDC102B,RPE,TMEM100,ATP8B4,WLS,CSRNP3,SCN2A,SGK1,SH3GL3,RUFY2,ZNF430,BTBD7,SPHKAP,SLC22A4,SMARCE1,TTC17,LIMCH1,SNRPN,ENKUR,GLT8D1,KDM4C,BEX1,KIF1B,C11orf87,SSTR2,ZSCAN29,NEK4,DIP2A,FGD4,ARC,DDHD2,DNMBP,FAM208A,TCEA1,TCF4,USP22,PCDHB6,FRYL,TEX15,DICER1,SIRT1,ZFPM2,BHLHB9,TMPO,C5orf64,TPM4,RFTN2,EIF4ENIF1,UBE3A,PITPNB,MTCH1,NSD2,WRN,CLDND1,XRCC4,ZNF708,KCNT2,ZNF138,SMARCAD1,STOX2,PRDM10,RGS7BP,AMN1,FZD3,PHTF2,ADAMTSL3,NHSL1,FRMD6,GAN" MicroRNA hsa-miR-1979:mirSVR_highEffct hsa-miR-1979:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-83 6.75E-80 5.97E-83 5.50E-82 215 895 "PSMG3-AS1,BRAP,SLC12A5,ERMN,NLGN4X,PCDH19,ALCAM,CEP126,LRCH2,PPFIA1,PHYHD1,MADD,ZFYVE28,CAPRIN2,RASL11B,ALDH7A1,BACH1,ADGRB3,SEC11C,RGS9,DST,BTRC,CAMK2D,SLC25A14,RUNX1T1,CBLN1,CCKBR,TMEM257,CDC27,LRRFIP1,CDH18,MAGI1,CFL2,MS4A7,NRXN3,PLAA,NRXN1,NIPBL,AKAP6,SLC4A8,RCHY1,AHCTF1,HAPLN1,ANKRD44,RGS6,NCAN,ERC2,CYBB,GSDME,SMG7,NTM,USP3,DTNA,DNAJB6,DNM1L,EDNRB,SEMA3D,KMT5B,EIF1,VPS13B,SRRM1,EFS,SPEG,ZIC4,EFEMP1,FCGR1A,FER,POLR1B,FGF12,FHL1,SUCO,TPK1,STAG2,MEGF10,GAB1,GABRB1,GALNT15,GALC,ZNF559,WASF3,PCDH17,GLI2,RAB30,GLUL,CBX1,GPD2,TDRKH,GPR12,CECR2,GRIA2,GRIA4,TMEM25,AP4S1,RNFT2,ADAMTS6,RASSF8,HAS2,NXPH2,AGBL5,HNMT,ZIC5,DOCK7,DIPK1A,KLRC2,STXBP5,L1CAM,HECTD2,MAOB,MBNL1,MDM4,MEF2C,MEIS1,KCTD6,MIA2,KITLG,ZNF680,NDP,NEK1,NINJ2,NKX2-2,NPTX1,OCRL,ZNF827,CDK18,PDE4D,GNG2,PFKFB2,NLGN3,XRN1,GPSM2,HMGCLL1,LRP12,HYDIN,VPS13C,GON4L,CNTLN,MTMR10,PXK,PTPRB,PTPRD,PEX5,SLC25A48,RAD51D,RASGRF2,SLC6A15,ERI2,RFX3,RNASEL,SETD5,EXD2,CCDC102B,ZNF568,SOX6,ITSN1,FRMPD1,HKDC1,FNDC3A,FAM214B,KANSL3,SLC8A3,BTBD7,SLC20A2,ATF7IP,SMARCE1,RCOR3,SNAP25,TNIK,UHRF1BP1L,KDM4C,KIF1B,TSPYL2,COLGALT2,SMOC1,ZSCAN29,SEPT8,FGD4,VPS13A,SYN1,SYP,PDLIM2,TBCEL,ATMIN,ZFP90,ZEB1,SZT2,DOCK9,AP4E1,TLL2,TMPO,TP53BP2,METTL3,RUNDC3B,AMACR,TRPS1,DCBLD1,ANKRD20A2,SSBP2,ZKSCAN5,AMOT,UGT8,PLEKHH2,VLDLR,WIPF1,ZNF781,ZNF138,EML6,FTSJ1,PCDH15,KCNAB1,MVB12B,JMJD1C,KLHDC1,NETO1,SLC4A10,ZNF30" MicroRNA hsa-miR-649:mirSVR_highEffct hsa-miR-649:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-83 7.98E-80 7.04E-83 6.48E-82 224 970 "SYN3,NBAT1,ACTN2,FAM43B,BRAP,SORCS1,KIAA1211,ALCAM,AMPH,CDC42BPA,DDO,API5,USP37,SHTN1,CDK10,NUMB,TMEM108,ATM,BBS2,PROM1,MTMR2,JAZF1,IL33,KALRN,TMEM257,CDH10,JAM2,COG1,LY86,SLC25A27,SLC4A8,TOGARAM2,CP,GDA,CSNK1G3,ATRNL1,ERC2,PHF14,CTNND2,NRSN1,RIMS2,RUBCN,EDRF1,HDAC9,GAPVD1,ZFYVE16,EARS2,DAPK1,PABPC5,CEP170,BLOC1S6,SNAP91,CHRDL1,DMD,DMTF1,DPP6,PDCD6IP,DYRK1A,DNM1L,GOLT1B,EBF1,YAF2,FAM13A,KMT5B,EGR3,EIF4G2,ELAVL3,C8orf37,DCTN4,EIF1,EMX2,VPS13B,MFSD10,NCALD,CDKL3,WAC,SCML2,GORAB,PCYOX1,SGIP1,JKAMP,SORBS1,ATP2C1,NRG3,ABLIM2,TVP23A,STAG2,DKK3,INPP5K,NEU3,SESN1,KIAA1958,GPD2,GPM6B,CECR2,PCLO,CNTRL,STMN2,GRIK2,NR3C1,FRMD3,BACH2,HLF,HMGB1,HTR2A,IRF8,MYLK2,ZIC5,INPP5B,KCNK1,KIF5A,LIMS1,MARK1,MARK3,MBD1,MBNL1,KITLG,MID1,MTTP,NAP1L3,NCAM1,NDUFA5,SLCO1C1,NFE2L2,SLC11A2,NRCAM,NUMA1,OCRL,OGG1,OPA1,GPR137C,PDE4D,SLC10A4,SERPINE2,ANLN,MAPKAP1,PRKAB2,VPS13C,GON4L,PSMD13,ZNF615,RAD52,OXR1,RASGRF1,SLC6A15,ZYG11B,GTDC1,ARHGEF10L,TTLL7,CCDC102B,ACER3,RPS6KA2,NCBP3,TRAPPC13,SCN2A,FAM19A1,NLGN4Y,SH3BGR,CHD9,R3HDM2,WDR37,FAM81A,PPP4R3A,KDM4D,CCDC88A,TET1,LIMCH1,RIMS1,PALLD,FAM126B,MYT1L,SOX2,SOX5,LMO3,POGZ,SS18,KANK1,SYT1,SYT4,TAC1,ANKRD12,CAMSAP2,FAM208A,ADGRL3,TBCEL,ANO4,ZEB1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,AP4E1,ERCC6L2,R3HDM1,C9orf85,CADM1,UBE2H,SLC35A4,FLRT2,BCL2L13,CCDC14,CLDND1,PCDH20,ZNF711,ZNF19,KCNT2,AGMO,REEP1,ZSCAN26,ANKS1B,EVI5,FAM47E,PDSS2,AMN1,PHTF2,ZNF248,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-124*:mirSVR_highEffct hsa-miR-124*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.89E-83 1.06E-79 9.34E-83 8.61E-82 228 1005 "FMNL2,CDC7,PWWP2A,PTCHD1,TAOK1,OGT,DPP10,PPFIA1,APC,GPAM,MIER1,ASPH,SLC4A4,DPY19L3,TTLL9,CFLAR,PROM1,ARHGEF7,JAZF1,RAB29,CACNA1E,DDR1,KALRN,PTBP2,SLC25A14,PRC1,CBS,CLDN10,P2RX6,TMEM257,LRBA,DCLK1,CDO1,CHGA,CHN1,CHN2,CASC2,NRXN3,PLAA,CLCN4,ABCG2,NIPBL,ARHGEF6,FAM149A,SLC25A27,FAM171B,CRHBP,CS,MICAL2,OSBPL3,SIPA1L1,SLITRK5,USP6NL,HDAC9,GPRASP1,DGKB,DAPK1,ALKBH8,RHOBTB1,HS3ST2,CPEB2,DMTF1,DTNA,ABCC9,AASDH,USH1C,PLEKHA1,PAN3,TUBD1,EPB41L2,KCNMB2,RACK1,SUCO,FOXG1,CAP2,SORBS1,HVCN1,ATP6V1H,CELF1,DACH2,OGA,MEGF11,CHL1,BRPF3,JPH4,C15orf41,GCNT2,ARFIP1,MMADHC,KIRREL3,LYVE1,GK,CRCP,DBF4,CBX1,RAB40B,ZNF782,GPM6A,STON1,DIDO1,GRM7,KIF3A,LINC01551,ADAMTS6,GYG1,IRAK3,VSIG4,HNMT,HNRNPK,USP51,OPALIN,SOWAHA,ZIC5,RBPJ,LIX1,TUBB2B,ZNF385B,SLC35G1,KCND2,KCNN2,LMO2,MAP4,MARK3,IL17D,LRP1B,MRPL42,MSR1,MTTP,MTR,NAP1L3,NCAM1,NF1,NTRK2,OXTR,PBX1,PCDH9,PDE3B,PDE4B,PDGFRA,RETREG1,HMGCLL1,TRHDE,LRP12,ING3,PPP2R5E,PPP3CB,RASGEF1B,PRKCZ,SAMD9,MDGA2,PTK2,PID1,TMEM255A,SLC25A48,USP47,ARID4A,BSDC1,REV3L,GTDC1,RGS4,RNF220,CARF,CCDC102B,SOX8,TRAPPC13,AMER2,ATXN2,SCN2A,SCP2,FUZ,MAGI3,CHD9,ST6GAL1,ANKRD6,DHX30,RUFY2,SHANK2,SLC12A2,SMARCE1,LIMCH1,SNAP25,UNC80,PDZD2,KIF21B,SP2,IDI2-AS1,TAB2,LARP4,ADHFE1,PRRC2C,FNDC9,ANKRD28,MMS19,MTCL1,SEMA4A,FAM208A,ADGRL3,CUX2,ZEB1,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,ZFPM2,DDHD1,NR2E1,BEX4,STXBP4,DCBLD1,TSC1,SSBP2,HIRA,BEST1,SLC13A3,ZNF19,CELF4,PLPPR5,WNK1,ZXDA,TMEM163,LINC00632,CAB39L,ACTR3B" MicroRNA hsa-miR-563:mirSVR_lowEffct hsa-miR-563:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-83 1.16E-79 1.02E-82 9.37E-82 207 833 "RALGAPA1,ABAT,CLK4,ERMN,PCDH19,HACE1,TXNDC16,SPARCL1,PCDH10,BBOX1,AMPD2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,UPRT,SHTN1,PPP4R4,CADPS,TMEM108,SLC4A4,ATP1B3,ATP2B3,ADAM23,DNAJC27-AS1,SYNJ2,MTMR2,IL33,BTRC,PTBP2,BRSK2,RUNX1T1,PRC1,TMEM257,CDH8,TJP2,HECTD1,MAP4K4,IGLON5,AKAP6,HS3ST5,ZNF385A,CLIP3,SEC24C,VCAN,CNTNAP2,PPP1R16B,PHF14,CTNND2,PUM1,DCAF4,GAPVD1,MATR3,TMEM170A,TOMM20,JAKMIP2,ZEB2,SV2B,SGSM2,NR1D2,DMTF1,DPP6,DTNA,DNAJB6,E2F5,PHF20L1,EIF5,CALCRL,VPS13B,GPHN,ADGRV1,RACK1,STRADA,ZNF589,SYNCRIP,NOP56,UFM1,ATP2C1,STAG2,MEGF10,ZNF234,GAP43,DISC1,ATP8A2,ARFIP1,LYVE1,PCDH11X,ZNF638,ADGRA3,GPD2,GRIA1,SPACA9,LINC00839,GYG1,HAS2,MAN1B1,HSPA1L,FAM95B1,SOWAHA,RBPJ,IGSF1,SCIN,LRRTM3,KCNMA1,KCNN2,MAN2A2,ADAM22,MSR1,MYO7A,PABPC1L2A,HNRNPM,NDUFA5,NEUROD1,ALDH1L2,NOVA1,DNHD1,HCN1,SETD4,CHAMP1,OPA1,CNTN3,PCDH9,PDGFRA,NALCN,HMGCLL1,PRIMPOL,RC3H2,ING3,EPB41L4B,SH3KBP1,DRAM2,PPP3CC,PRKCZ,GRAMD1C,HYDIN,GON4L,ANKHD1,UHRF1BP1,PTPRE,USP47,FAT4,KHDRBS2,ERI2,RIC8B,TMEM100,RPL15,LRRK2,WLS,RTKN,RYR3,SALL1,TNFRSF19,SLC30A10,SOX6,SUPT20H,SCG5,KIF21A,NTNG1,SHC4,FNDC3A,WDR37,ABLIM3,SLC2A5,KANSL3,RAB3GAP1,ATF7IP,SLN,GKAP1,IFT122,KIF13A,PDZD2,TRERF1,SOX15,GLT8D1,SPTAN1,TAB2,ATP10B,POGZ,ITPRID2,PHLDB1,CAMSAP2,UNC5D,ALG1,ADGRL3,KLHL4,SATB2,TRIM2,CRB1,HHIP,TIAM1,TLL2,BHLHB9,TRO,PPIL6,TSN,TTC3,CADM1,TBC1D15,XPO1,ZBTB16,REEP1,AMZ1,DPYSL5,WNK1,EMSY,STOX2,LMAN2L,C12orf4" MicroRNA hsa-miR-4273:mirSVR_highEffct hsa-miR-4273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.30E-83 1.29E-79 1.14E-82 1.05E-81 241 1118 "FMNL2,ADCY8,BEND6,MTUS1,KLHL13,AGT,OSBPL1A,CC2D2A,OGT,DPP10,PKP4,USP37,CDK10,ASPH,ATM,EIF4G3,STX16,N4BP2L1,TTLL9,BACH1,MPDZ,CALM1,CAST,MTMR7,SEPT7,CDC27,CDH8,LARGE1,NOG,CHM,CHN2,JAM2,SLIT2,IGFBP7-AS1,PPT2,NRXN1,QKI,CNR1,ARMC8,AKAP6,BTF3L4,ACBD5,CNRIP1,CDC42BPB,RBM39,AKAP12,HAPLN1,GDA,SNCAIP,ERC2,PHF14,BOC,GPRASP1,MATR3,KIAA0586,GIT2,C8orf34,FBXL5,LYPD1,SPOCK3,AK5,SGSM2,DMD,USP3,DPH1,ECM2,EDN1,SGK2,HIPK3,RBM12,FAM13A,ABI2,CALCRL,SEZ6,EPHB1,ENPP6,GPHN,F5,CLVS1,WAC,RPS6KC1,CACNG2,ACSL4,TOMM40L,PRMT5,GORAB,FOXG1,IQCG,FOXM1,ANKFY1,NOP56,NELFCD,SORBS1,HVCN1,PDLIM5,STAMBP,MSANTD4,AP4B1,SDCBP2,ZMAT1,GABRA2,ILDR2,GAD2,AHCYL1,ATP8A2,KIAA1841,NEU3,TUBGCP4,PCDH17,RAB30,TNRC6A,PCDH11X,CCDC184,MCHR1,STMN2,GRB10,DIDO1,PLCD4,GRM1,CIT,LINC01551,PSIP1,GUCY1A2,MAP4K5,MIER3,GABARAPL2,HNMT,NEGR1,EID2B,DOCK7,LRRCC1,ITPKB,OLFM3,KCNMA1,KCNN3,KLC1,STMN1,INSYN2,NCOA7,MAP4,MATN3,MBP,SYT9,MDM4,MEIS1,MID1,MOBP,CTNNA3,MTTP,NEFH,NEUROD1,NKX2-2,SLC11A2,NRCAM,OPA1,GLIPR1L2,PDE3B,PDE1B,PDGFRA,PDPK1,PURG,SCHIP1,SLC36A4,PPP1R1A,PKN2,MASP1,CNTLN,BDNF-AS,TMEM260,PTPRN,PPP2R3C,RGR,RNASEL,ATP8B4,ATAT1,AP1AR,DGLUCY,SEMA6D,ATXN7,SCN8A,SH3GL3,FUZ,HKDC1,CHD9,SLITRK3,SLA,PPP4R3A,FAM214B,SLC8A3,SLC12A2,ZFP1,SORCS3,CABCOCO1,SNRPN,PALLD,SOX2,CLUAP1,SPP1,ATP10B,CLSTN2,POGZ,RGL1,SYNE2,TACR1,CAMTA1,TAL1,TMEM136,MGRN1,TBX15,TCF12,WASHC4,WDR7,GPRIN3,PMS2CL,CRB1,C18orf54,MTMR14,NR2E1,TRPS1,CA14,ANKRD20A2,TTPA,ZNF610,BCL2L13,VLDLR,WRN,ZNF711,MICU3,MKRN3,CELF4,ZNF225,FAM47E,SLC17A6,PDSS2,RGS7BP,FZD3,PAK5,KAT6A,RNF170,IFT88,CBLN2" MicroRNA hsa-miR-103-as:mirSVR_lowEffct hsa-miR-103-as:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.38E-83 1.33E-79 1.17E-82 1.08E-81 249 1189 "DGCR6,KCNH8,NCKAP5,XKR4,CSMD3,NDRG2,CCDC85A,GALNT13,ADD1,ADD2,KIDINS220,TXNDC16,HFM1,SRPX,UNC79,CDC42BPA,ANK1,LRCH2,ANK3,USP28,PPFIA1,PKP4,APC,API5,PPP4R4,SPTBN4,CDK13,CAPRIN2,NCOA1,ATP1B3,MTMR9,NOL4,DPY19L3,ADAM23,DST,BTK,SCAPER,C5,CACNA1B,DDR1,CACNB4,CAMK2A,CAMK2G,SLC25A14,VSTM2A,INA,CBFA2T2,TMEM257,CDH10,ZMYM4,CLGN,CFL2,FOXN3,JAM2,LSMEM2,COG1,MYL6B,FHL5,ARMC8,COX4I1,HS3ST5,CLOCK,CRY2,LRIG1,MICAL2,ATRNL1,PDE4DIP,KIAA0040,CTNND1,ST18,FGFR1OP2,RIPOR2,ZFYVE16,TOMM20,SCRN1,ARMCX4,ZEB2,MFAP3L,SRGAP3,EXOG,USP3,DSCAM,DNAJB6,ABCC9,E2F5,SYT15,FAM13A,EIF4G2,ELN,EPHB1,STX2,IGSF6,F5,SCML2,FECH,FER,KIAA1109,FGFR1,UBE2E3,EFCAB2,WDR83,HVCN1,ERGIC3,DLL3,ABLIM2,OGA,GABRA2,DISC1,CSDC2,GGTA1P,GGT7,LYVE1,COPS8,GLI2,TNRC6A,STARD3,LUZP2,DCLK2,GNAS,PRUNE2,GPM6B,ATF7,LPAR4,GRIA1,PLCD4,LINC00839,AP4S1,FAM107A,MAP4K5,CELF3,GPR45,FRMD3,HMGB1,GABARAPL2,MSL1,IL11RA,STXBP5,LIMS1,SYTL4,HECTD2,MARK1,COL28A1,BLOC1S2,BCO1,MSRA,RSPO2,NCAM1,VWA2,OLR1,OPCML,PBX1,PDE2A,PFKFB2,ZDHHC8,GDAP1L1,XRN1,ST8SIA5,PLP1,PLXNB3,PRIMPOL,ING3,PPM1B,PPP2R5E,RASGEF1B,MAPK9,ZYG11B,TRIM68,REV3L,PRRT2,GTDC1,FIGN,RFX4,SLC25A36,ZFHX4,TMLHE,GSTCD,ROBO2,CNTNAP3,RYR3,HOGA1,SCP2,SOX6,KIF21A,FRMPD1,MYO18A,AMBRA1,NUBPL,WDR37,ABLIM3,PREX2,WDR47,CCDC88A,SLC14A1,LMBRD1,PALLD,SON,SOX5,ZSWIM8,SP4,MYCBP2,KDM4C,IDI2-AS1,ZNF423,SPTB,SPART,NFASC,SAMSN1,LARP4,NKAIN2,CEP68,SULF2,SYT1,COBL,UNC5D,TBCEL,TMEM136,VWA3A,ATMIN,ZEB1,SYNE1,AKNA,HEY1,BHLHB9,TMPO,NPL,TPM3,C9orf85,SYNPO2,STXBP4,RPL7L1,FAM155A,AMOT,FLRT2,USP1,TOM1L2,FMN2,LYPD6,ZNF177,WNK1,SLC38A1,SNX27,WIPF2,PHTF2,RSPRY1,ZNF248,RNF170,FXR1,LAS1L,SENP7" MicroRNA hsa-miR-381-3p:TargetScan hsa-miR-381-3p TargetScan 2.64E-83 1.49E-79 1.31E-82 1.20E-81 177 608 "CPNE2,KIAA1211,HACE1,ARHGAP20,LRFN1,CDC42BPA,ANK3,APC,DGKD,APP,CCAR2,EIF4G3,ATP2A2,DOCK11,NRP2,MAGI1,DLGAP2,NRXN3,NRXN1,FAM19A5,HECTD1,BTF3L4,ABI3BP,ACBD5,CLOCK,AKAP12,CLIP3,OSBPL3,PLXNA4,APPL1,GREB1,KIAA0408,GAPVD1,ARHGAP24,DCC,FAM107B,GRIN3A,RAB39B,DMTF1,EBF1,KCTD3,EIF4G2,RGS17,EML1,PAN3,EIF1,EPB41,EPB41L1,RCAN2,EPS8,ERBB4,F3,DLC1,FGF1,PCYOX1,PSD2,NBEA,MSANTD4,MPP6,FYN,DKK3,GABRB1,GABRB3,GABRG1,FAM184B,GAD1,NCKAP1,FAXC,GFRA1,MALT1,RAB30,GLS,GLUL,KDM2B,GPR34,GPR37,CECR2,GRIA1,RFFL,NR3C1,GRM5,GRM8,KIF3A,IL1RAPL1,PSIP1,FAM222A,KLF12,HMGB1,HMGCR,AGFG1,RBPJ,SCIN,JAK2,KCNH1,KCNJ3,KCNQ3,MAP4,MARK1,MATN2,MBNL1,MEIS2,PPM1L,MITF,AFF1,MN1,MXI1,NASP,NCAM2,NEUROD1,NFIA,HCN1,DDR2,PBX1,PCDH8,PCSK2,PDE1C,PFKFB3,KCTD15,FA2H,FAT3,PPP2R2C,PPP2R5E,KANSL1,CEP41,PKIA,ANKHD1,ELOVL2,EML5,MARCH1,RAP1GDS1,GTDC1,RFX3,NUDT11,RPRD1A,RORB,AP1AR,AMER2,SALL1,SATB1,CSRNP3,SCAF8,CHD9,R3HDM2,BTBD7,EPC1,CXXC4,MYCBP2,KIF1B,IQSEC2,NFASC,LMO3,LRRC4,ANKRD12,FAM208A,ANO4,CUX2,PSD3,NSD1,AKNA,CRTC1,GPRIN3,HHIP,NACC2,CBX5,DDHD1,R3HDM1,KAT6B,RBFOX2,NR2C2,CADM1,DNALI1,PPP1R3F,ITM2C,FZD3,ADAMTSL3,MSRB3,JPH3" MicroRNA hsa-miR-556-5p:mirSVR_highEffct hsa-miR-556-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.86E-83 1.61E-79 1.41E-82 1.30E-81 228 1007 "RALGAPA1,ABAT,XKR4,NDRG3,SORCS1,ADRA1D,KIDINS220,SLC44A5,KCTD16,WDR35,OGT,LCORL,PKP4,APC,DDO,TMEM263,NUMB,ATP2B1,ADGRB3,KSR1,DST,ST3GAL5,CALB2,MAP7,RUNX1T1,CLDN10,INA,LGI1,CHM,JAM2,NDST3,NGEF,FBXO7,TJP2,CNTN1,AKAP5,SLC4A8,ACBD5,MFSD4A,SEC31B,SEC24C,MICAL2,CSNK1G3,PHF14,PUM1,CYBB,DOCK4,ARHGAP32,GAPVD1,FRMPD4,TBC1D5,ZEB2,HEPH,MAGI2,DDX46,SACS,G3BP2,FAM107B,OLIG1,NYAP1,CDON,DMTF1,DPYSL2,ECM2,DNAJB6,DNM1L,USH1C,FAM135B,ANKRD46,SGK2,TMTC1,FSD1L,OPTN,FAM13A,PHF20L1,ASB3,PAN3,SRRM1,CDKL3,GMPR2,F8,RACK1,ZSCAN30,SEC23B,RGPD5,SGIP1,UFM1,STAU2,DOT1L,CHL1,GABRG2,ZMYND11,SULT1C4,WASHC2A,ZNF276,RAB30,GLS,TNRC6A,MAP7D2,GPD2,NR3C1,GUCY1B1,AGBL5,NEGR1,HSF2,LRRCC1,USP54,IGSF1,LIX1,ITPKB,JAK2,OLFM3,KCNK1,KHK,CREG2,MAN2A2,MAT2A,MBNL1,SYT9,LDLRAD3,MN1,MOBP,CD200,COMMD5,RSPO2,MXI1,NEUROD1,NF1,OTOGL,SLC11A2,NUCB2,CLDN11,PDE1A,PDE4D,BEST3,A2ML1,PMP2,STRN3,EXOSC10,PRRX1,MINDY2,PPP2R5E,PPP3CB,VPS13C,LRRC49,TMEM104,CNTLN,PTHLH,TMEM260,RAP1GDS1,RDX,RET,RNF220,ZFHX4,SETD5,EXD2,CARF,MRAP2,NEK11,ADAL,MAP6D1,LRRK2,ZNF568,MAGI3,FNDC3A,SLC4A3,SLC14A1,SMARCE1,LIMCH1,RIMS1,CMTR2,FNBP1,KDM4C,ZC3H13,BEX1,KIF1B,STOX1,STXBP1,AJAP1,SYT11,TAC1,MTCL1,CNTN2,TBCEL,TBL1X,SATB2,RPGRIP1L,USP22,WDR7,PCDHB6,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DICER1,TJP1,ERCC6L2,TMPO,CSMD1,C5orf64,C9orf85,RUNDC3B,ANKRD20A2,TSC1,RFTN2,CLHC1,HEPACAM,ZNF610,UGT8,DNAJC12,SLAIN1,MEAF6,AGMO,CELF4,RNF103,PPP1R3F,FIP1L1,WNK3,PDSS2,SMIM8,PHTF2,CASC15,NLRP3,NETO2" MicroRNA hsa-miR-18b:mirSVR_highEffct hsa-miR-18b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.11E-83 1.74E-79 1.53E-82 1.41E-81 193 726 "KCNH8,AS3MT,SLC25A25,TMCC3,ADD3,PLEKHH1,PWWP2A,BEND6,GPR158,ALCAM,BCAR3,ANK3,MAP4K3,ANXA7,CNTNAP1,VAT1L,NCOA1,ATM,ATP1B3,NAE1,CA8,CA12,ZNF501,USP6,SYNGR3,LRBA,CDC42,LRRFIP1,CASC2,NRXN1,COG1,QKI,SLC25A27,COL9A2,TBPL1,AHCTF1,RNF14,CLIP3,RGS6,ATRNL1,SIPA1L1,SOCS5,DZIP3,GREB1,NRSN1,PUM1,RIMS2,DCAF4,DOCK4,HDAC9,PHF19,LIN54,MATR3,TOMM20,DBI,PITPNC1,HP1BP3,SNAP91,TMCC2,SEC16A,DTNB,SYT15,PHF20L1,SORBS3,VPS13B,EPB41L1,EPHA5,EFS,TLR7,DLC1,CEP78,MED12L,FGF1,FGF12,SUCO,FOLH1,KHDRBS3,STAU2,B3GAT1,OGA,CAB39,WASF3,SULT1C4,PPARGC1A,GLRB,STARD3,GNAS,GPM6A,GPM6B,NR3C1,MAEL,ARHGAP36,HLF,HNMT,ZNF491,ZDHHC15,HSF2,SOWAHA,INSYN2,MBNL1,OCRL,GPR88,PCSK1,PDE1A,PDE4D,PDE1B,GPR173,CDK14,PIK3C2A,ZNF655,SNX10,EXOSC10,PRRX1,SH3KBP1,PPP3CB,PRKACB,MAPK4,HYDIN,DIRAS2,MASP1,VPS13C,SIDT1,SNRK,IQSEC3,NWD1,RBBP6,RBBP8,MORC4,FIGN,ARHGEF10L,RNASEL,AMER2,SATB1,CSRNP3,LINC00461,ZFP30,ITSN1,MAGI3,ZNF365,SLC6A11,RAB3GAP1,SMARCC2,MBD5,DOP1A,SON,PDZD2,KDM3A,KDM4C,TEX2,IDI2-AS1,BEX1,CDK19,TSPYL2,SPART,C11orf87,ATP10B,NKAIN2,NXT2,CEP68,FGD4,VPS13A,TMEM150C,ANKRD28,C12orf76,ZFP90,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,TEK,TJP1,TLL2,DAAM2,NPL,PLEKHH2,VSNL1,WIPF1,ZBTB14,TRIM9,CELF4,SYNC,EMSY,CADM2,ADAMTS9,ITM2C,EPM2A,MSRB3,CBLN2" MicroRNA hsa-miR-365*:mirSVR_lowEffct hsa-miR-365*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.13E-83 1.76E-79 1.54E-82 1.42E-81 222 957 "ASPHD1,ACTN2,TMEM132B,GALNT13,ADD1,ADD3,PNMA8B,SORCS1,NLGN4X,C1QTNF3,USP35,TRMT9B,ZFAT,FGD2,CCDC146,SUGT1P4-STRA6LP-CCDC180,PARG,EPB41L5,APLP1,UPRT,APP,PPP4R4,PLA2G4C,STK33,MARK4,ASPH,ATP1B3,SLC2A11,KSR1,ARHGEF7,TRIM41,RUNX1T1,CBS,CERS5,ARHGEF1,CBFA2T2,EVI5L,LOC730101,SOCS6,ASIC3,CHRM1,NRXN3,CLCN3,DGCR9,LY86,ARHGEF6,ARMC8,NECTIN3,SLC35F1,RBM39,CRY2,CLIP3,SNCAIP,TENM4,CSF1R,OSBPL3,IPCEF1,ERC2,PHF14,RUBCN,CCDC144A,GPRASP1,ARHGAP32,ARHGAP24,TOX,MAML1,SIRPA,ARMCX4,PITPNC1,HP1BP3,DLG3,RAB39B,CDON,SLC12A6,SLC25A18,DTNA,SUGP2,EGFR,MRO,CALCRL,ZNF549,F8,PTK2B,TUBB4A,CORO2B,ATP8A1,FHL1,SUCO,FOXG1,ERGIC3,AP4B1,NRG3,CHL1,HBS1L,GALC,GHDC,NCKAP1,SEPT9,LRRC37A6P,CPLX2,SRCAP,RAPGEF1,GRIA4,PLCD4,GRM7,BTN2A1,GSTM5,BVES,PTGDR2,BACH2,HSD17B1,IL6R,KCNJ9,ZFYVE27,MAP6,MARK1,MBP,TM6SF1,MEIS1,MID1,ERICH3,MYO9A,ZC3H12B,NFYA,NRGN,NTRK2,GPR88,P2RX7,PAH,TREM2,PDCD2,PDYN,BEST3,OLA1,ZNF655,PSAT1,SDK2,POLR2F,TMEM235,PPM1B,PTPA,PPP3CA,RASGEF1B,PROX1,BCAS3,SLC22A23,PIGG,ZSCAN2,TTC13,RASGRF1,BSDC1,RFX2,KCTD17,CARF,CYB561D1,FBXW7,GLDN,ABCA11P,AMER2,SEMA6D,FAM19A1,LINC00461,TRIM46,RASA3,ST6GAL1,CTXN2,WDR37,SLC1A3,SIRT2,KBTBD4,MAST1,SORCS3,SMARCD3,DOP1A,WDTC1,TRERF1,UHRF1BP1L,KDM4C,UNC5B,PEG10,RBM26,NFASC,SRPK2,APOM,PHLDB1,TAC1,KIAA1107,FBXW11,KLHL4,MGRN1,ATMIN,SATB2,TCF7,TRIM2,AZIN2,HIF3A,ITGB3BP,AP4E1,AKTIP,TLL2,HEY2,PIK3R5,TPM2,SSBP2,RFTN2,GORASP1,LINC00689,PITPNB,FLRT1,PLPPR2,SLC13A3,MKRN3,ZNF213,PRDM10,ADAMTS9,SLC17A7,SLC17A6,DOCK8,UBE3B,CERS6,SSPN,CBLN2" MicroRNA hsa-miR-142-5p:TargetScan hsa-miR-142-5p TargetScan 3.39E-83 1.90E-79 1.67E-82 1.53E-81 186 674 "ARID1A,CSMD3,RNF150,HECW2,OSBPL6,ALCAM,ABCD2,MAP4K3,GAS7,ALS2,CASK,ASCL1,CADM3,DCAF5,MTMR2,CACNA1B,CALM1,CAMK2A,CAST,ISPD,RUNX1T1,LDB2,KRIT1,REPS2,LRWD1,NOG,QKI,ARHGEF6,CNTN1,ARMC8,AKAP5,FAM171B,CLOCK,C2CD2,CRY2,CNTNAP2,APPL1,PUM1,FAM131B,MAML1,DNAL1,CEP170,MAGI2,RHOBTB1,SACS,MTX3,FAM107B,DLG2,DMD,CALN1,CDON,CPEB2,DRD1,ABCC5,EDNRB,CACNG7,EGR3,ELAVL2,CERCAM,ELAVL4,RGS17,MTSS1L,ETV1,MED12L,FGF12,NBEA,PDLIM5,FAM49B,ATP2C1,NSG2,NSG1,MPP6,GALNT15,BRPF3,NCKAP1,GK,GPR75,LUZP2,GPR26,GPR37,RAPGEF1,DIDO1,RFFL,CIT,RNF165,BVES,FRMD5,MIER3,DHX35,CELF5,HTR2A,IGF1,IL6ST,ITGAV,JAK1,KCNA4,KCNB1,KCNJ3,KCNJ10,KCNK1,KCNQ3,KIT,IPO5,CHIC1,LRP1B,MEIS1,MEIS2,KITLG,MITF,DBNL,MXI1,MYCN,MYO9A,NFIA,NFE2L2,PAX6,PBX1,PDGFRA,PFKP,HMGCLL1,LRP12,SCHIP1,PPP3CA,PROX1,CNNM2,PTPRB,PTPRD,CEP97,ATG16L1,RBBP6,RBBP8,REV3L,FIGN,RIC8B,PBRM1,RNH1,ROBO1,RIMKLA,RTN1,ATXN1,SCN2A,FAM19A1,FNIP1,HSPA4L,CPEB3,MAGI3,CHD9,CCDC92,EPN2,ARHGEF40,BTBD7,RIMS1,MBD5,MYT1L,C11orf87,CLSTN2,FCHO1,FAM168A,NECAB1,FGD4,C3orf70,ANKRD12,CAMSAP2,FAM189A1,ARHGEF12,PUM2,HHIP,DDHD1,KAT6B,RGMB,ELP5,HEPACAM,CADM1,FAM155A,CADM2,LRP8,RGMA,PRDM8,PRDM10,FIP1L1,GOPC,FAM219B,JMJD1C,MSRB3,NETO2,NETO1" MicroRNA hsa-miR-4289:mirSVR_highEffct hsa-miR-4289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.68E-83 2.07E-79 1.81E-82 1.67E-81 202 796 "ABAT,KCNH8,ABHD6,NBAT1,ACTN1,KLHL32,ERMN,PWWP2A,INTS2,WDR35,ALCAM,FAM135A,ZFAT,PHF12,ANXA7,SEMA4G,TMEFF1,ASCL1,ADGRB3,DST,SYNJ2,KALRN,VXN,RUNX1T1,LDB2,TMEM257,CDH2,LRRFIP1,CFL2,RCBTB2,SOCS6,SYNPR,JAM2,NDST3,PLAA,C4orf33,SLC4A8,HS3ST5,HAPLN1,TRIM69,CS,MROH8,TENM4,SEC24C,ATRNL1,VCAN,ERC2,ST18,FRMPD4,ZFYVE16,IP6K1,DCC,SPATA2,ZEB2,CNIH3,CEP170,SPOCK3,AK5,RABGAP1L,GRIN3A,USP3,CPEB2,DTNA,EDN1,EDNRA,AASS,GOLGA7,RCAN2,FER,FGF14,ATP13A4,NPTN,CELF1,GAD1,ZMYND11,GALR1,ERAP1,C15orf41,HEPN1,BRD8,KIAA1958,ZNF782,FERMT2,LILRB4,GRIA2,GRIA4,GRIK2,FAM19A2,MFSD2A,ADAMTS6,WIF1,RASSF8,HPS5,SYNPO,ZDHHC15,ZNF546,BRINP3,KCND2,KTN1,SYTL4,ARHGAP12,MATN3,SYT9,MEIS2,MN1,MRPL42,CTNNA3,MTTP,MXI1,MYT1,NCAM2,NEK1,SLC11A2,TBC1D25,OMG,OXTR,PDE4B,SLC10A4,BEST3,PLCL1,PLP1,PCDH18,TNPO2,PKIA,MASP1,PTHLH,CEP97,USP47,FAT4,ARID4A,MSANTD2,SLC6A15,KLHDC8A,CARF,RPE,LRRK2,ABCA11P,KCNIP2,CLIP1,SALL1,SEMA6D,SCN8A,SCP2,SELL,PPM1E,FERMT1,CPEB3,NTNG1,SLA,ZNF365,LIMS2,RUFY2,ZNF334,SLC15A2,TMEM132D,SMARCE1,RCOR3,LIMCH1,MBD5,FAM126B,UNC80,SON,TRERF1,THSD1,FAM168A,PLCB1,SYT1,COBL,SATB2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,GZF1,TIAM1,TLR4,RIMBP2,CSMD1,TPM3,SMUG1,TRIO,TMEFF2,CADM1,EIF4ENIF1,USP1,VSNL1,CADM2,DNALI1,RNF103,PCDH15,WNK2,PARP11,FAM13C,DOCK8,RNF170,FRMD6,CBLN2" MicroRNA hsa-miR-502-5p:mirSVR_highEffct hsa-miR-502-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.11E-83 2.31E-79 2.02E-82 1.86E-81 211 868 "ABCF1,ACADM,FMNL2,ADD2,ADD3,BEND6,CC2D2A,SEMA6A,AMPD3,OGT,TNRC6C,BRINP2,ATP1A2,SLC4A4,RIPK1,RGS9,CFLAR,CALB2,CAST,INA,AIFM1,DGKI,LRBA,CDC27,MAGI1,CHN1,CASC2,NRXN3,KIAA1549L,CLCN4,CNGA3,FHL5,CNR1,AKAP7,IQCK,PCYT1B,HS3ST5,RBM39,SH2B1,RNF14,NCOR2,GDA,SNCAIP,ARHGEF10,CST3,PLXNA4,RIPOR2,ZFYVE16,MATR3,DAPK1,ARMCX4,ALKBH8,SMG7,SACS,SV2B,DTNA,ABCC5,E2F5,WDPCP,EDN1,FAM135B,PHC2,KMT5B,EIF4G2,PLEKHA1,ELAVL3,PAN3,EPHA5,CEP85L,PIPOX,EXTL2,GMPR2,FAM198B,ACSL4,ZSCAN30,FDFT1,SEC24B,FGF12,SGIP1,SLC37A3,C2orf88,AKAP3,CELF1,MSANTD4,TBR1,PHYHIPL,TXNL4A,RAB30,MSL3,PCDH11X,MAP7D2,WDFY3-AS2,TDRKH,RAPGEF4,C1QL4,GRIA4,RFFL,GRM5,FAM19A2,RASSF8,LINC01102,MIER3,USP51,SMAP1,EID2B,MSL1,IDH3B,IGF1,ZNF678,JAK2,SLC35G1,KCNB1,KCND1,KCNK1,KCNN2,MAT2A,MATN2,SYT9,KITLG,ADAM22,ZNF92,MXI1,NEK1,SLCO1C1,NFE2L2,CNOT4,CLEC9A,NUCB2,GPR88,PCSK5,PDE3A,PFKFB2,CDK14,A2ML1,MTRF1L,PPARA,MED1,PPM1B,PRKCZ,EPDR1,DCHS2,PTCH1,TMEM260,PTPRD,PTPRE,FAM120C,ZNF844,CEP97,ACSS3,FAM66C,FIGN,RGS10,SETD5,CCDC25,TCP11L1,SCN2A,FAM19A1,TNFRSF19,IL17RB,CASC3,FHOD3,NUBPL,PAAF1,ZNF365,DHX30,RUFY2,ZNF430,TET1,SMARCE1,ANKRD36,SNCA,KIF13A,PDZD2,SOX3,KIF1B,MCF2L2,NFASC,SRPK2,CLSTN2,NUDT10,ADGRL3,TBCEL,ANO4,TBX15,ATMIN,ZEB1,WDR7,RALYL,OBSL1,CYB561A3,SIRT1,DICER1-AS1,TJP1,ASXL3,TPM1,ZNF384,TSN,SLAIN1,FLRT1,ZNF709,XPO1,PCDH20,CELF4,ADAMTS9,PCDH15,MVB12B,PARP11,UBE3B,CAMK1G,JMJD1C,RSPRY1" MicroRNA hsa-miR-664*:mirSVR_highEffct hsa-miR-664*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.53E-83 3.10E-79 2.71E-82 2.50E-81 220 943 "AS3MT,ADD1,ERMN,KIAA1211,ADORA3,RNF150,KIDINS220,AP2A2,AK2,LRRC7,MRTFA,APC,DGKZ,APP,MARK4,DDX3Y,TMEM108,ATP1B3,ATP2A2,BACH1,JAZF1,CANX,SYT6,NFS1,CCNH,DGKI,SEPT7,CDC27,MAGI1,TIGD7,CLGN,SOCS6,MS4A7,NIPBL,ARHGEF6,AKAP6,SLC4A7,SLC4A8,ZFP28,CP,ANKRD44,TRIM69,MICAL2,CSNK1E,ERC2,UBXN2A,PHF14,PNPLA8,CFAP61,PUM1,RIMS2,USP6NL,NOS1AP,BOC,TBC1D5,IST1,DGKB,JAKMIP2,DGCR5,RAB39B,HS3ST2,RPS6KL1,DYNC1I1,DPYSL2,DTNB,KRBA2,SNX29,WDPCP,RASGRP1,PHF20L1,CALCRL,PAN3,KCNMB2,SLC43A2,TMEM74,ZNF589,FGF12,FGF14,POLK,FOXF2,FLT1,ANKFY1,SMC2,NPTN,CELF1,ZNF44,GABRB1,TRAF3IP2,FAM184B,DENND2A,KIAA1841,GCNT2,TUBGCP4,GLS,PCDH11X,INSM2,LUZP2,GRIA1,GRIK2,LINC01551,MAP4K5,ZHX1,FRMD5,HMGB1,GABARAPL2,HMGCR,HNMT,SMAP1,LIX1,ITPKB,KCNN1,MAP4,MBNL1,MITF,ERICH3,N6AMT1,MTTP,MYO7A,NCAM1,NELL1,NF1,NFE2L2,ALDH1L2,SMIM11A,GPR88,CHAMP1,CLDN11,PRTG,PDE3B,PDE1B,ZFYVE21,TMEM38A,ZNF426,ANKRD16,MINDY2,PRKACB,CNTLN,ACSM5,PPP2R3C,SLC25A48,CCDC40,PLEKHB2,RASGRF1,SLC6A15,ZYG11B,RGS3,LGI2,CARF,TMEM100,MCMBP,ATP8B4,PRR5L,LGR4,FAM192A,ZFP30,SH3GL2,FNDC3A,NLGN1,SLA,ZNF365,SLC14A1,EFHD1,RCOR3,ANKRD36,RIMS1,SOX3,KIF21B,ZSWIM8,SP4,CLUAP1,TAB2,TROVE2,POGZ,SS18,ACSBG1,ZFR2,SYNE2,SYT1,MTCL1,DDHD2,ALG1,TBCEL,ANO4,EHBP1,DMXL2,AKNA,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,RNF216P1,C18orf54,AP4E1,TGFBR3,AKTIP,TMPO,KCTD2,SYNPO2,ELP5,CLHC1,SGK3,CADM1,WIPF1,CLDND1,RICTOR,ZNF74,MKRN3,TCEAL7,INTS3,RGS7BP,TIGD6,SSPN,SLC4A10,GAN,SENP7" MicroRNA hsa-miR-143*:mirSVR_highEffct hsa-miR-143*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.17E-83 3.47E-79 3.02E-82 2.79E-81 190 706 "ASIC2,DPY19L2P4,KLHL13,ALAD,SMIM17,MARCH4,OGT,APC,BCAS1,API5,SEMA4G,CASK,CADPS,ASPH,NCOA1,DDX3Y,B3GALT2,NOL4,ST3GAL5,LDB2,MTMR7,AIFM1,ARHGEF2,ADGRG1,TPP1,FBXO7,ABCG2,QKI,FHL5,ABI3BP,RCHY1,CP,CHD1L,FAM171B,ANKRD44,NCOR1,FEZ2,SLITRK5,GAPVD1,ARHGAP24,ZNF337,ARMCX4,HP1BP3,MAGI2,PLPPR4,SACS,DTNB,DYRK1A,EGFR,PLXNC1,PLEKHA1,MTSS1L,SRARP,EYA1,NRN1,PRMT5,FGF1,SCARA3,C2orf88,CELF1,MSANTD4,OGA,GABRA1,GABRB1,GAD1,HBS1L,ARPP21,GLS,KDM2B,GRIA1,PLCD4,ADAMTS8,GRM7,MAP4K5,ZHX1,FRMD3,MIER3,SCRG1,HSP90AA1,SMAP1,C5orf24,RBPJ,ZNF678,NME9,SLC35G1,KCNN2,STMN1,C2orf80,MAT2A,MATN2,TM6SF1,LRP1B,ERICH3,PABPC1L2A,NELL2,DNHD1,PCSK5,CDK14,NLGN3,PIK3C2A,FAM216A,PURG,TRHDE,SCHIP1,MINDY2,MAPK9,GRAMD1C,VPS13C,GDPD2,CNTLN,PTHLH,TMEM260,PYGM,FAM184A,ZNF493,RBBP6,ZYG11B,REV3L,RGS7,ZFHX4,C12orf49,KLHDC8A,RAVER2,RORB,MRAP2,LRRK2,RYR3,DGLUCY,SATB1,SLC30A10,SHC4,FAM81A,RUFY2,KANSL3,CCDC88A,BTBD7,SORCS3,RCOR3,SNCA,UNC80,DOP1A,MYT1L,KDM3A,SP2,ZSWIM8,KDM4C,IDI2-AS1,NPAS3,CLASP2,POGZ,LARP4,KAZN,CAMTA1,ANO4,ATMIN,WASHC4,ZFPM2,CRB1,THRA,ERCC6L2,SEZ6L,TPM3,TRIO,KCNE5,TMPRSS5,ANO5,FAM155A,PITPNB,LMF1,P2RY12,NSD2,PCDH20,ZBTB14,ZNF19,TRIM9,ZNF45,FMN2,ZNF138,LAMP5,SMARCAD1,CA10,MAP3K12,EMSY,SLC38A1,WNK3,C12orf4,KAT6A,ADAMTSL3,NETO2,JPH3" MicroRNA hsa-miR-646:PITA hsa-miR-646:PITA_TOP PITA 6.50E-83 3.65E-79 3.19E-82 2.93E-81 151 437 "RALGAPA1,ASIC1,ADRA1B,KLHL13,TAOK1,BIN1,CNTNAP1,CACHD1,APP,CDC14B,ARHGAP5,NOL4,JAZF1,CAMK2A,CANX,SYT6,FMNL3,CDC42,DCLK1,KMT2C,NRXN3,HECTD1,TMEM155,AKAP6,BTF3L4,AHCTF1,ACBD5,CREB5,ARHGEF10,ATRNL1,CTNND1,USP6NL,GAPVD1,FRMPD4,IST1,DCC,MFAP3L,CEP170,ZC3H11A,SMG7,SRGAP3,G3BP2,DLG3,ARRDC4,DYRK1A,FAM135B,FRY,RBM12,PAN3,RCAN2,DMTN,ANKRD13B,TAOK3,DLC1,FLNC,AFF2,SYT3,NBEA,NPTN,TPPP3,GABRG2,CAB39,AHCYL1,BRPF3,SALL3,DNER,PPARGC1A,GRM7,HRH3,MIER3,ELOVL5,ACOT7,SMAP1,NKD1,ZIC5,USP54,KCND1,KIF2A,KIF5A,INSYN2,PACRG,MAP2,MAPT,KITLG,MOV10,CCDC80,RTL5,NEXMIF,NEUROD1,NOVA1,OCRL,GPR88,PCMT1,PDGFRA,PDPK1,GNG2,ANLN,PIK3R1,NXPH1,PRKCG,PKN2,MAPK4,ZFHX4,SETD5,ROBO2,RYR3,SCN2A,PRCD,KIF16B,AMBRA1,CHD9,FNDC3A,CLSTN1,CPEB4,TMCC1,FAM126B,WDTC1,MYT1L,SOX5,KIF21B,ZSWIM8,ZBTB43,CLASP2,RGL1,KANK1,GANAB,FAM168A,PRRC2C,MTCL1,CAMTA1,CAMSAP2,SMG6,WSCD1,SATB2,WASHC4,AHCYL2,NACC2,NR2E1,ERCC6L2,TNS1,RBFOX2,TPM3,KCNE5,WIPF1,PCDH20,TMEM237,CADM2,GAL3ST3,RTN4,FXR1,GAN" MicroRNA hsa-miR-631:mirSVR_lowEffct hsa-miR-631:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.15E-82 6.44E-79 5.61E-82 5.17E-81 243 1144 "SYS1,GALNT16,ADD2,PWWP2A,DPY19L2P4,ZNF578,SPARCL1,CARNS1,PITPNM2,OGT,ANK1,MAP4K3,MYH7B,PPFIA4,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,CDK10,TMEM263,IGDCC4,SPTBN4,PCDHGB4,NCOA1,NUMB,ATP6V1G2,SNAI3-AS1,BID,PROM1,KSR1,ARHGEF7,MMD2,CACNA1D,DDR1,LURAP1,PTBP2,MAP7,USP6,IGFN1,CASC2,CHRNB2,PLAA,NMT2,DGCR9,DNAJB5,RAB26,CHD1L,ZNF385A,CREM,ENTPD4,SEC24C,NCAN,ERC2,CTH,GREB1,CFAP61,FAM131B,SEC14L5,CCDC144A,EARS2,PHYHIP,DAPK1,MFAP3L,POM121,DLX1,RAB39B,DNM1,USP3,NR1D2,DNM2,ATN1,E2F5,CNNM1,HEYL,PHF20L1,EGFR,ING4,ELAVL3,DMTN,IGSF6,ZNF549,MRPL37,MRPL10,SIRPB1,KATNAL1,TOMM40L,TESK2,ZNF589,FER,FGF11,BAIAP2,FOXG1,PSD2,FLYWCH1,EFCAB2,TPK1,RASL10A,STAU2,GHDC,DISC1,GATM,AHDC1,HEPN1,CRCP,LPAR4,GRIN2C,GRM1,LINC01551,MAN1B1,LINC01102,BACH2,ELOVL5,HNF4G,TCEAL6,IRF8,IDH3A,ZNF546,RBPJ,ZNF385B,JAK1,KCNJ9,A1BG-AS1,SYTL4,MATN2,MBD1,MBNL1,ADAM11,MEF2C,KITLG,AFDN,MSI1,TAGLN3,LAYN,MYO7A,NCAM1,ZC3H12B,VWA2,CNOT4,NOVA2,NUCB2,NUMA1,PC,DPY19L2P2,PCDHGC3,PDE1B,PIRT,PDGFRA,SLC10A4,SEMA5B,FAM218A,EPB41L4B,PPP2R5C,CEP41,MAPK9,MASP1,WBP1L,MDGA2,ZSCAN32,C1orf109,ZSCAN2,NKAIN1,MARCH1,RAB5B,CCDC40,RASGRF2,PRRT2,MRPS18A,RPRD1A,ZFHX4,C12orf49,CARF,CCDC25,FBXW7,SGSM1,KCNIP2,CSRNP3,DRAXIN,ITSN1,SHC4,HKDC1,MAGI3,ZNF365,SLC6A11,SLC8A3,ARHGEF40,SLC12A4,SMARCA4,INAVA,RIMS1,MBD5,FAIM2,DOP1A,PDZD2,CAND2,ATP10B,CLASP2,ZC4H2,NKAIN2,SSPO,NSFL1C,SYT1,PDLIM2,PCDHGC5,PCDHGB7,PCDHGB6,CLASP1,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,CYB561A3,CRB1,AP4E1,SLC44A1,TNFRSF1B,CABIN1,TP53BP1,TPD52,WBP2,NR2C2,TRIO,ZMYND8,RUSC1,TTTY15,TUBB1,PLPPR2,BEST1,KLC2,ZNF154,TMEM237,LAMP5,PLPPR5,SMARCAD1,SLC30A4,EMSY,ADAMTS9,URM1,PHTF2,PRRT4" MicroRNA hsa-miR-4313:mirSVR_lowEffct hsa-miR-4313:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-82 6.82E-79 5.94E-82 5.47E-81 254 1243 "TTYH1,ASPHD1,SYS1,KDM5D,XKR4,ADARB2,ADCY6,BRAP,SLC12A5,SNX32,KIAA1324,LTBP4,GOLGA7B,FAM135A,KCNT1,MRTFA,ZNF687,CNIH2,BCAS1,MADD,IGDCC4,SPTBN4,CADPS,LINC00173,PDE8B,STK33,RASL11B,DPY19L3,ADAM23,TTLL9,RGS11,CFLAR,BMP7,SYNJ2,GPC2,BSN,CA12,HAP1,SLC25A14,CAST,CARS,USP2,CD86,ENTPD6,AP4M1,ARHGEF2,L3MBTL4,DIS3L,CHM,EPS15L1,PPT2,NRXN2,CLU,MYL6B,TJP2,HECTD1,WHRN,SMARCAL1,ZNF385A,SH2B1,HAPLN1,SLC32A1,CS,SEC24C,MICAL2,IPCEF1,PDE4DIP,PPP1R16B,CMTM5,UBXN2A,ZFYVE16,DAPK1,AIF1L,COPS7A,KLHL3,CCDC3,DMD,SLC25A18,DNM1L,KRBA2,E2F6,SEZ6L2,WDPCP,FAM135B,KLHL5,CACNG7,ING4,C3orf18,EN2,SEZ6,SLC43A2,SPEG,MRVI1,EZH1,DLC1,KAT8,KIAA1109,SPSB4,POLK,SCARA3,AGAP2,EVL,STAMBP,CAMKK2,ZNF605,STAU2,AP4B1,BRSK1,ZNF44,GABRB1,SEPT9,MSTN,GFER,GGT5,TTBK1,RND1,TNRC6A,AIFM3,STARD3,MAP7D2,LILRB4,GRIA2,GRID1,ADAMTS13,GRM7,PTPN5,MFSD2A,LINGO1,TNFAIP8L3,INSYN1,SYNPO,SHISA6,C2orf72,ITPKA,ITPKB,STXBP5,L1CAM,INSYN2,LMO1,HECTD2,LSS,MAOB,MAP4,MATK,CD200,NRBP2,THYN1,SCG3,LYRM9,HNRNPM,NEFM,NEUROD2,DNHD1,PCBP3,NUMA1,TBC1D25,OGDH,P2RX7,PDE4B,PHKG1,CAMKV,A2ML1,TMEM38A,ST8SIA5,HMGCLL1,RC3H2,NECAB2,SEPT4,MED1,TATDN3,CRLS1,NKAIN4,MAPK10,WBP1L,WDR25,CNTLN,TMEM260,PTPRH,PEX5,RASGRF1,BSDC1,RET,RNF220,RIC8B,PBRM1,CYB561D1,CCDC102B,SNX22,ZC3H14,EMID1,MEG3,DGLUCY,ATXN2,TRIM46,MRAS,RASA3,FRMPD1,FERMT1,AMBRA1,ST6GAL1,SLITRK3,ST3GAL3,PEX26,FAM214B,SLC6A8,RADIL,SLC9A5,SLC11A1,SLC12A4,SLC14A1,SNRPN,WDTC1,TSNAXIP1,SOX10,IQSEC2,NPAS3,TROVE2,LRRC4,STAC2,SUPT5H,ZFR2,ALG1,SYNE1,PHF24,TNS2,SIK3,RNF216P1,TK2,TLL2,LRRC8A,TMPO,FAM124A,R3HDM1,TNR,TRH,ELP5,ZMYND8,TMEFF2,CADM1,RPL7L1,UBTF,BEST1,NPDC1,ZIC1,ZNF708,AGMO,REEP1,MAP3K12,DNALI1,XKR7,PCBP4,NUP214,FAM219B,GAN" MicroRNA hsa-miR-509-3-5p:mirSVR_highEffct hsa-miR-509-3-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-82 7.87E-79 6.85E-82 6.31E-81 219 939 "RALGAPA1,ACLY,CSMD2,BRAP,OSBPL1A,TAOK1,LRRC7,AMPD2,MAP4K3,ALS2,VAT1L,CDC14B,ASGR1,NUMB,B3GALT2,DPY19L3,ADGRB3,ARHGEF7,THSD7A,PTBP2,CAMK2D,RUNX1T1,ZNF501,KRIT1,METTL6,INA,CD38,LRBA,ARHGEF2,LRRFIP1,NPIPA1,SRSF11,TMEM155,CNTN1,FAM149A,AKAP6,COL4A5,ZNF521,ENTPD4,TRIM69,SIPA1L1,PHACTR3,CTNND1,KCTD8,DDX46,SACS,G3BP2,WDR20,CHRDL1,HS3ST4,USP3,DPYSL2,DTNB,GOLT1B,EDIL3,EDN3,YAF2,EGR3,KCTD3,VPS13B,COQ7,ABCA8,CORO2B,TOMM40L,MED12L,GTF2IRD2,OLFM1,SPSB4,BAIAP2,TMEM164,FHL1,SYNCRIP,RGPD5,JKAMP,ZCCHC17,TMEM107,SMC2,ST6GALNAC3,FYB1,GALC,IP6K3,ATP8A2,NEU3,TUBGCP4,MSTN,ARFIP1,SESN1,GHR,TOX3,TNRC6A,MSL3,PCDH11X,WDFY3-AS2,ADGRA3,GPM6B,TDRKH,FUT10,GRIA2,GRIA4,GRM1,CLASRP,IL1RAPL1,IRAK3,UBE2QL1,ZHX1,NXPH2,LINC01102,HMGB1,HSP90AA1,IL6ST,ZNF678,KCND2,SYTL4,HECTD2,MBNL1,MDM4,MEIS1,MN1,COL28A1,MRPL42,MTTP,NAP1L1,NF1,NRCAM,NRDC,NRGN,SETD4,OGG1,PCDH8,PDGFRA,ENPP2,GPR85,GNG2,CCSER2,RETREG1,MAPKAP1,RC3H2,LRRN3,PPP3CB,KANSL1,PRKACB,MAPK9,RELN,BCAS3,SPDL1,PTPRB,PTPRD,PTPRE,PTPRZ1,NKAIN1,RADX,MORC4,GTDC1,FIGN,ZFHX4,CCDC82,CARF,RPL15,UEVLD,CNTNAP3,RYR3,NCBP3,SCN2A,SCN7A,ASIC4,PEAR1,CASC3,SCAF8,KIF21A,ITSN1,SH3GL2,FBXO11,FNDC3A,NLGN1,RAB3GAP1,SLC15A2,ATF7IP,TET1,RCOR3,LIMCH1,SNAP25,USP33,FNBP1,KDM3A,CLUAP1,KDM4C,ZNF423,TAB2,CLASP2,SSPO,NECAB1,SYN2,SLC37A2,FBXW11,EHBP1,ZEB1,TRIM2,RPGRIP1L,PCDHB7,ITGB3BP,TLL2,ERCC6L2,ANO5,TMEFF2,VLDLR,RICTOR,SF1,ZNF24,FMN2,LYPD6,POLR3H,LAMP5,UPF3A,MFF,STOX2,SNX27,FIP1L1,UBE3B,KAT6A" MicroRNA hsa-miR-455-3p:mirSVR_highEffct hsa-miR-455-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.52E-82 8.55E-79 7.43E-82 6.84E-81 213 890 "SDE2,KCNH8,FMNL2,ADD2,ADORA2A,KIDINS220,NLGN4X,ZNF608,LRRC7,OGT,DPP10,PPFIA1,PKP4,PARG,TMEFF1,ARRB1,ASPH,DYNLL1,ATP1B3,N4BP2L1,NOL4,DOCK11,ADGRB2,OSGIN2,KALRN,SPAG9,CCNH,ZBED1,MAGI1,TIGD7,NUMBL,SOCS6,CASC2,LHX2,KMT2C,CLTC,FBXO7,TJP2,C4orf33,HECTD1,TMEM155,ARMC8,SLC25A27,CNRIP1,FAM171B,PNKD,ANKRD44,TRIM69,CSF1R,CSNK1G3,SUSD5,PDE4DIP,SLITRK5,CYBB,HDAC9,ZFYVE16,ZEB2,MYEF2,MFAP3L,SNAP91,EDNRA,PHC2,ANKRD46,FCF1,FRY,APH1A,SRPK3,TMEM35A,EML1,EIF1,EPB41L2,EPHB1,ETV1,RTN3,F8,PTK2B,POLR1B,NELFCD,ARFGAP2,STAU2,MEGF11,DKK3,GABRA2,GABRG2,KIAA1841,ARFIP1,TOX3,LILRA2,CECR2,GRIA2,GRIK2,PSIP1,RASSF8,HAS2,FRMD3,TNFAIP8L3,GABARAPL2,AGBL5,IDH3A,DIPK1A,KCNJ16,KIF5A,STXBP5,LAMP2,STMN1,ARHGAP12,PACRG,AFDN,COMMD5,ADAM22,SCG3,CTNNA3,NELL2,NOVA1,NRCAM,NRGN,IGSF11,PAX6,PCSK5,PDCD2,PDGFRA,HERC2P3,ABCB1,PIK3R1,RETREG1,PLCB2,JAKMIP1,MAPKAP1,FSD1,PPP2R5E,PPP3CA,PKN2,GRAMD1C,MASP1,RELN,SYTL2,CNTLN,PTAFR,BDNF-AS,OXR1,HKR1,DPF2,RET,RFX4,UBR7,PBRM1,CARF,TMEM206,YY1AP1,PCMTD2,ATP8B4,SALL1,SATB1,ATXN7,TNFRSF19,ARX,NLGN1,PEX26,KANSL3,SLC12A2,SLC22A4,ZNF667,CDK5RAP2,RCOR3,KIF1B,CDK19,RBM26,ATP10B,SMOC1,SS18,TTBK2,DIP2A,VPS13A,SYN1,C12orf76,TACR1,ACSL6,DMXL2,ZEB1,RPGRIP1L,SLC19A3,PUM2,SIK3,SIRT1,AP4E1,SLC44A1,ARL10,KAT6B,AMACR,ANO5,CLDND1,XPO1,MICU3,CELF4,SPIRE1,LAMP5,EMSY,CSDE1,PARP6,STOX2,SLC17A7,KCNAB1,MPPE1,SLC17A6,PLSCR4,C12orf4,RTN4,NHSL1,IFT88,CBLN2,SLC4A10,GAN,CPNE4" MicroRNA hsa-miR-609:mirSVR_lowEffct hsa-miR-609:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.64E-82 9.21E-79 7.99E-82 7.36E-81 229 1024 "RALGAPA1,KCNH8,ABR,EMILIN3,SYS1,PSMG3-AS1,KIAA1211,LRFN2,KIAA1324,CC2D2A,LRRC7,USP35,PITPNM2,DDO,ASPH,TMEM108,TTLL9,ADGRB1,SNAI3-AS1,BMP7,BSN,CACNB2,CACNG1,CAST,MAP7,TMEM257,ARHGEF2,CDC42,NUMBL,CHGA,CHRNB2,KMT2C,NRXN3,IQCK,BTF3L4,IGDCC3,SLC32A1,TRIM69,RASGEF1C,SLITRK5,KIAA0040,HDAC9,MYADM,LONRF1,DAPK1,SPOCK2,PLEKHM1,CEP170,LYPD1,RHOBTB1,SNAP91,SV2B,RAB39B,DNM1,CPEB2,GNE,DTNA,MAMLD1,DNAJB6,E2F5,EDN3,FCF1,TMTC1,FAM13A,PHF20L1,EGFR,SORBS3,STARD3NL,EN2,VPS13B,EPB41L2,STX2,SPEG,HSPA12B,ACSL4,STRADA,TMEM164,AMOTL2,EVL,SGIP1,POMT1,TMEM107,ST6GALNAC3,DLL3,NRG3,SDCBP2,GABBR1,ARPP21,C15orf41,DISC1,CPLX1,IGSF5,TTBK1,STARD3,LILRA1,PRLHR,TPPP,GRIA2,BTN2A1,KIF3A,MAEL,LINC00667,DIPK1A,KCNJ9,KCNK2,KCNK3,KCNN2,KIF5C,KLC1,ASPRV1,MAP4,LYPLAL1,MBP,ADAM11,LDLRAD3,MEF2C,MMP16,MN1,MYO6,FXYD6,NME4,CNOT4,NTRK3,OPCML,SNTG1,PDE3A,RETREG1,GPSM2,FTO,SLC25A23,PLXNB3,PMS2,ING3,SH3KBP1,DRAM2,PPP2R2B,PPP3CB,PRKCB,MASP1,DEF8,QRICH1,PIGG,PTCH1,PTPRD,FAM120C,PTPRZ1,RAB3IL1,FAM66C,ATG16L1,KHDRBS2,ERI2,UBR7,RGS7,PBRM1,KIRREL1,SGSM1,CLIP1,SEMA6D,TRIM46,SUPT20H,MYO18A,NTNG1,FHOD3,ST6GAL1,ABLIM3,ZNF365,SLC1A3,RUFY2,SLC6A1,SLC8A1,SLC8A3,SLC22A4,SMARCA4,IFT122,SNCA,PALLD,MYT1L,DOK5,KDM4C,KIF1B,C11orf87,CLASP2,SMOC1,NCDN,ZC3H4,PRRC2C,ARC,TACR1,TAL1,UNC5D,FBXW11,SZT2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,PMS2CL,DICER1,TGFBR3,LRRC8A,RBFOX2,RASD2,TPM1,DOK6,PRMT8,TRPC1,FNDC5,DCBLD1,TSC1,LRTM2,FAM155A,OSBP2,USP1,NPDC1,ZBTB14,TRIM9,EMSY,EVI5,ADAMTS9,FAM47E,C12orf4,NUP214,RNF170,PIANP,SPATA13" MicroRNA hsa-miR-29a:mirSVR_highEffct hsa-miR-29a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.83E-82 1.03E-78 8.91E-82 8.21E-81 228 1016 "KCNH8,RBM10,NCKAP5,KDM5D,XKR4,ADD3,CDC7,GRAMD1B,PTCHD1,OSBPL6,TXNDC16,BCAR3,LCORL,SUGT1P4-STRA6LP-CCDC180,PARG,APC,GPAM,TMEFF1,CDK13,CAPRIN2,ASPH,DACT3,BRINP2,STX16,ATP2A2,ATP2B1,N4BP2L1,ADGRB2,PROM1,DST,WASF1,MMD2,PTBP2,CAMK2D,VSTM2A,TIGD7,MS4A7,CNR1,ARMC8,COL4A5,COL9A1,SLC4A7,SLC4A8,CPS1,CREM,CRMP1,HAPLN1,GDA,TRIM69,CRYM,CS,LRIG1,SOCS5,USP6NL,TCAF1,DCAF8,KIF26A,GIT2,DNAJC6,ZEB2,RHOBTB1,SV2A,EXOG,GRIN3A,DYNC1I1,DNM1L,EDNRB,FEM1B,SH3GLB1,PHF20L1,KMT5B,ELN,TUBD1,ANKRD13B,RTN3,SCML2,EFEMP1,MED12L,GTF2IRD2,MEX3B,RGPD5,DCTN2,TPK1,ST6GALNAC3,OGA,STAG2,DKK3,GABRG2,ARPP21,DISC1,SESN1,GK,RAB30,TNRC6A,FERMT2,ADGRA3,TDRKH,EML4,GPR37,PCLO,ADAMTS6,ZHX1,HRH3,VSIG4,HMGCR,HNF4G,HNRNPK,IGF1,IGSF1,ZNF678,LRRTM3,KIF5A,LAMA2,LIMS1,HECTD2,MAP6,MARK1,MEST,MYCN,NEXMIF,NAP1L3,NASP,NCAM1,OTOGL,OPHN1,PDGFRA,ENPP2,GNG2,CCSER2,PLP1,HMGCLL1,PURG,PMP22,SDK2,ING3,EPB41L4B,MED1,PRKAB2,RASGEF1B,MAPK9,SLC26A11,VPS13C,SNRK,PTHLH,SPDL1,TMEM260,PTX3,RAP1GDS1,OXR1,RADX,REV3L,FIGN,RFX3,NUDT11,RNASEL,CCDC82,ROBO1,PCMTD2,FBXW7,SALL1,SFPQ,TRA2B,SGK1,SH3GL3,CPEB3,SEC31A,NUBPL,DHX30,RAB3GAP1,NAPB,ELMO2,BTBD7,TET1,ZKSCAN3,MYO16,HECW1,KDM4C,SPTAN1,KIF1B,NPAS3,TAB2,NXT2,ZSCAN29,ELOVL4,FGD4,PRRC2C,SYP,TBCEL,TCF4,WDR7,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,DICER1-AS1,ZFPM2,AP4E1,ENHO,HEY2,R3HDM1,TPM1,FNDC5,TSN,TUBB2A,CLHC1,UGT8,ZNF19,ZNF28,ZNF45,NDRG4,EML6,DPYSL5,PLPPR5,SLC30A3,EMSY,STOX2,ADAMTS9,NAV3,URM1,NAV2,CASC15,IFT88" MicroRNA "CAGTATT,MIR-429:MSigDB" "CAGTATT,MIR-429:MSigDB" MSigDB 2.19E-82 1.23E-78 1.06E-81 9.79E-81 150 434 "CSMD3,ADCY2,SLITRK1,MTUS1,ARHGAP20,TRMT9B,OGT,ANK3,MAP4K3,VAT1L,ARHGDIA,DDX3Y,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,NIPA1,MMD2,FOXK1,ZMYM4,NOG,CFL2,NGEF,DNAJB5,QKI,MAP4K4,CNN3,CNTFR,AKAP7,BTF3L4,CREB5,FEZ2,CSNK1G3,PHACTR3,CTNND2,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,ELAVL2,EPS8,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,FOXG1,SGIP1,CAB39,ARPP21,SESN1,COPS8,FERMT2,GPM6A,NR3C1,PSIP1,KLF12,HLF,HNRNPK,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,HECTD2,NCOA7,MAP2,LRP1B,JAKMIP3,MYCN,MYT1,NFIA,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PENK,ANLN,PKD1,KCTD15,PLCL1,SCHIP1,NXPH1,PPM1B,PPP2R2C,PPP2R5C,PRKACB,CEP41,PKIA,WBP1L,PTHLH,PTPN13,PTPRZ1,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,ATXN1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC1A2,SLC6A1,SLC14A1,NAPB,SNAP25,TMCC1,SCN3B,FAM219A,SOX1,SOX2,ZCCHC24,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,TMEFF2,VLDLR,ZIC3,SMARCAD1,EVI5,PARP6,NAV3,PAK5,PHTF2,CERS6,FXR1" MicroRNA "CAGTATT,MIR-200C:MSigDB" "CAGTATT,MIR-200C:MSigDB" MSigDB 2.19E-82 1.23E-78 1.06E-81 9.79E-81 150 434 "CSMD3,ADCY2,SLITRK1,MTUS1,ARHGAP20,TRMT9B,OGT,ANK3,MAP4K3,VAT1L,ARHGDIA,DDX3Y,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,NIPA1,MMD2,FOXK1,ZMYM4,NOG,CFL2,NGEF,DNAJB5,QKI,MAP4K4,CNN3,CNTFR,AKAP7,BTF3L4,CREB5,FEZ2,CSNK1G3,PHACTR3,CTNND2,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,ELAVL2,EPS8,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,FOXG1,SGIP1,CAB39,ARPP21,SESN1,COPS8,FERMT2,GPM6A,NR3C1,PSIP1,KLF12,HLF,HNRNPK,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,HECTD2,NCOA7,MAP2,LRP1B,JAKMIP3,MYCN,MYT1,NFIA,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PENK,ANLN,PKD1,KCTD15,PLCL1,SCHIP1,NXPH1,PPM1B,PPP2R2C,PPP2R5C,PRKACB,CEP41,PKIA,WBP1L,PTHLH,PTPN13,PTPRZ1,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,ATXN1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC1A2,SLC6A1,SLC14A1,NAPB,SNAP25,TMCC1,SCN3B,FAM219A,SOX1,SOX2,ZCCHC24,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,TMEFF2,VLDLR,ZIC3,SMARCAD1,EVI5,PARP6,NAV3,PAK5,PHTF2,CERS6,FXR1" MicroRNA "CAGTATT,MIR-200B:MSigDB" "CAGTATT,MIR-200B:MSigDB" MSigDB 2.19E-82 1.23E-78 1.06E-81 9.79E-81 150 434 "CSMD3,ADCY2,SLITRK1,MTUS1,ARHGAP20,TRMT9B,OGT,ANK3,MAP4K3,VAT1L,ARHGDIA,DDX3Y,ATP2A2,NRP2,GPR146,SYNJ1,JAZF1,NIPA1,MMD2,FOXK1,ZMYM4,NOG,CFL2,NGEF,DNAJB5,QKI,MAP4K4,CNN3,CNTFR,AKAP7,BTF3L4,CREB5,FEZ2,CSNK1G3,PHACTR3,CTNND2,MATR3,KCTD8,IP6K1,GIT2,KLHL3,NYAP1,DNAJB6,EGR3,GOLGA7,ELAVL2,EPS8,TUBB3,DLC1,AMOTL2,FHL1,MEX3B,FOXG1,SGIP1,CAB39,ARPP21,SESN1,COPS8,FERMT2,GPM6A,NR3C1,PSIP1,KLF12,HLF,HNRNPK,NEGR1,AGFG1,SCRT2,LRRTM3,KCND2,KCNK2,HECTD2,NCOA7,MAP2,LRP1B,JAKMIP3,MYCN,MYT1,NFIA,NFYA,CNOT4,NOVA1,NPTX1,PCDH8,PDPK1,PENK,ANLN,PKD1,KCTD15,PLCL1,SCHIP1,NXPH1,PPM1B,PPP2R2C,PPP2R5C,PRKACB,CEP41,PKIA,WBP1L,PTHLH,PTPN13,PTPRZ1,OXR1,ZNF532,FBXW7,RPS6KA2,SEMA6D,SBF1,ATXN1,SUPT20H,PPM1E,AMBRA1,CHD9,SLC1A2,SLC6A1,SLC14A1,NAPB,SNAP25,TMCC1,SCN3B,FAM219A,SOX1,SOX2,ZCCHC24,SPTB,CLASP2,MPRIP,RGL1,PHLDB1,STX1A,KANK1,SYT1,ANKRD28,FBXW11,TRIM2,CLASP1,PUM2,ZFPM2,TUBB2A,TMEFF2,VLDLR,ZIC3,SMARCAD1,EVI5,PARP6,NAV3,PAK5,PHTF2,CERS6,FXR1" MicroRNA hsa-miR-140-3p:mirSVR_highEffct hsa-miR-140-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-82 2.24E-78 1.94E-81 1.78E-80 211 878 "KDM5D,NDRG3,DSCAML1,SLC12A5,SLC44A5,AP2A2,GPR158,LRRC7,AMPD3,AQP4,ASPH,DPY19L3,BMPR1B,DST,BSN,CA8,KALRN,SLC25A14,CERS5,USP6,INA,CD38,C1orf52,DGKI,AP4M1,MAGI1,SYNPR,JAM2,QKI,MAP4K4,IQCK,SUMF2,MYRIP,ZFP28,HS3ST5,SLC35F1,SEC31B,ENTPD4,CSF1,CHD5,NCAN,SOCS5,CFAP61,CCDC144A,MYADM,ZFYVE16,SIRPA,HP1BP3,SV2B,SRGAP3,GRIN3A,DNM1,NR1D2,CPEB2,DMTF1,ABI1,FARSB,GOLT1B,AASDH,EDNRA,SGK2,YAF2,PHF20L1,KMT5B,ASB3,COQ7,CLVS1,NSRP1,FAM198B,SCML2,EFEMP1,ATP8A1,POLR1B,FOXG1,SYNCRIP,SGIP1,STAMBP,ATP6V1H,KHDRBS3,SARAF,NRG3,CHL1,ARPP21,DNER,SPIN1,MSL3,PCDH11X,ZNF638,DCLK2,GOLGB1,LILRA2,DIDO1,GRM2,WIF1,NXPH2,ARHGAP36,MIER3,HLF,HMGB1,SCRG1,HNF4G,HNMT,HSF2,HTR5A,KCNB1,KCNK1,LAMP2,NCOA7,MARK3,MBD1,MEIS2,KCTD6,MIA2,MOBP,ERICH3,NAP1L1,NAP1L2,NEK1,NF1,NFYA,NOVA1,DNHD1,TBC1D25,OCRL,PAK3,PCDH8,SLC10A4,OLA1,NOMO2,PKM,PLCB2,PURG,RC3H2,SCHIP1,MAGEL2,ING3,EPB41L4B,SH3KBP1,PPP3CB,RASGEF1B,PKIA,VPS13C,SIDT1,GON4L,CNTLN,ZIK1,NWD1,ZNF493,NUDT11,CCDC82,CARF,ROBO2,YY1AP1,PRR5L,LGR4,CLIP1,SCP2,KIF21A,PPP4R3A,SLC6A11,SLC12A4,ELMO2,SMARCC2,SNAP25,ZNF415,UNC80,SON,SOX2,DOK5,SP4,KIF1B,TAB2,SYNE2,VAMP1,VPS13A,PLCB1,TCEA1,TCF4,SIN3B,CUX2,ZEB1,DOCK9,CCDC173,SIRT1,ZFPM2,HEY1,TLL2,ERCC6L2,PRRT1,RBFOX2,LILRA4,UGT8,SLAIN1,USP1,WIPF1,P2RY12,RICTOR,PLPP4,ZBTB38,SYNC,SLC30A3,STOX2,NAV3,MVB12B,PDSS2,GOPC,FAM13C,ZNF248,VANGL2,FRMD6,CBLN2" MicroRNA hsa-miR-1908:mirSVR_lowEffct hsa-miR-1908:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.30E-82 2.41E-78 2.09E-81 1.92E-80 205 830 "DPF1,CPNE2,ASIC2,ACHE,CLK4,SLITRK1,ADCY6,ADORA1,OLMALINC,DISP3,PLA2G6,MRTFA,AMPD2,PHF12,CNIH2,DGKZ,DGKD,NT5C3B,PPFIA3,APP,CDC14B,MIER1,SEMA4G,PRX,MADD,ARRB2,LINC00173,ALDH4A1,CHID1,STX16,ATP6V0A1,TTLL9,GPR146,KSR1,CDK5R1,ARHGEF7,CACNA1E,RHBDL1,ARHGEF1,ENTPD2,DGKI,KCNAB3,CCPG1,CACNA2D2,ASIC3,TAOK2,EPS15L1,PPT2,CLU,IQCK,HS3ST5,ZNF385A,SLC32A1,CSF1,MICAL2,SLITRK5,PITPNM3,SDC3,KIAA0040,CFAP61,DBN1,DLG4,DNM1,NYAP1,FAM78B,TNK2,MFSD10,MTSS1L,ANKRD13B,RABEPK,RASL12,EXTL1,DLC1,FCGRT,FDFT1,OLFM1,AGAP2,FLT1,KBTBD12,ADGRA1,DOT1L,GHDC,INPP5K,CPLX2,ALDH1L1,TUBA8,GLYR1,STARD3,PCSK1N,GPD1,ATF7,GPER1,GRIN2C,GRIN2D,GRM1,KIF3A,PSIP1,SLC2A6,PACSIN2,HRH3,HPSE2,LRRC75A,SHISA6,MYLK2,KNDC1,C2CD4C,KCNJ11,GATD1,KIFC3,LINC00634,LRRC4B,SYT9,XRRA1,LYRM9,RTL5,RCOR2,NOVA2,SETD4,PALM,PDGFRA,GDAP1L1,CAMKV,NLE1,FXYD1,MTRF1L,CDIP1,PILRA,PPP5C,VSTM2L,PRKCG,RAB3A,SUSD4,RASGRF2,RFX2,RNF220,MYH14,SNX22,ATAT1,CLIP1,AMER2,TRIM46,ITSN1,SH3GL3,ST6GAL1,BCAN,CLSTN1,ABLIM3,FAM81A,SLC1A7,SLC6A9,SNCB,MAPKBP1,WDTC1,SOX1,KIF21B,SOX10,SP2,IQSEC2,MCF2L2,RAP1GAP2,C11orf87,NCDN,PHLDB1,STX1A,ZFR2,C3orf70,SYN2,TBX15,SATB2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,CDH22,FBXL16,GALNT17,TIAM1,RELL2,LRRC8A,KCTD2,RASD2,IL34,WBP2,ELP5,AMACR,TTTY15,VAV2,TOM1L2,VLDLR,LMF1,PORCN,ZIC2,ZNF19,ZNF70,SLC26A10,SPHK2,DPYSL5,WNK2,JPH3" MicroRNA hsa-miR-100*:mirSVR_highEffct hsa-miR-100*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.81E-82 3.26E-78 2.81E-81 2.59E-80 213 896 "RALGAPA1,ACTN2,XKR4,CSMD3,AXIN2,PWWP2A,BEND6,BCAR3,MARCH4,SEMA7A,LCORL,PPFIA1,ALS2,API5,APP,PDE8B,ZBTB10,B3GALT2,BACH1,CACNB2,PTBP2,SLC25A14,SYT6,CAST,LRBA,L3MBTL4,SRSF11,SYNPR,TAOK2,CLTC,HECTD1,CNN3,IQCK,PCYT1B,WHRN,ABI3BP,AHCTF1,TOGARAM2,CNRIP1,CRMP1,RNF14,LRRC3B,SOCS5,FAM169A,ERC2,PHF14,ARHGAP24,ZNF337,KIAA0586,KCTD8,ARMCX4,DCC,HEPH,CEP170,DDX46,DLX1,USP3,MED12,CDON,DPH1,DTNA,ABCC5,EBF1,SNX29,SH3GLB1,MRNIP,CALCRL,DENND4A,RTN3,SCML2,FGF14,SUCO,SYNCRIP,NBEA,APOPT1,UFM1,SARAF,OGA,GABRA2,FAM120B,DNER,SRCAP,GGTA1P,GHR,PPARGC1A,SPIN1,GLUL,TDRKH,FUT10,GRIA2,GRIA4,PLCD4,KIF3A,MFSD2A,PSIP1,PACSIN2,DHX35,ZNF678,ITGAM,JAK2,KCNC1,SYTL4,HECTD2,NCOA7,PACRG,ZFYVE27,MEIS1,SRSF12,AFDN,ZNF680,THYN1,LAYN,MYO9A,NCAM2,NDUFA5,IDNK,NEK1,NEUROD1,NF1,VWA2,HCN1,OLR1,PAH,GLIPR1L2,PCDH9,PCSK1,PDE2A,CYTL1,ST8SIA5,PCDH18,PRIMPOL,EXOSC10,PRRX1,PACSIN1,SH3KBP1,MINDY2,PRKCZ,PSMA6,SIDT1,PTCH1,PTHLH,OCIAD1,PTPRD,EML5,TMEM255A,OXR1,RASGRF1,RASGRF2,RBBP6,GTDC1,RFX3,ZFHX4,TMLHE,EXD2,CARF,RORB,PCMTD2,CCDC102B,RPL15,BAALC,LRRK2,SCN2A,SCN7A,FAM19A1,SOX6,TRA2B,SH3GL2,FERMT1,SHMT2,CHD9,FBXO11,R3HDM2,PREX2,NAPB,ATF7IP,SPHKAP,MYT1L,TRERF1,SOX3,TNIK,SOX5,ENKUR,MCF2L2,POGZ,NEK4,ADHFE1,SYPL1,KAZN,DNMBP,TCEA1,SATB2,TCF7,TCF12,BEX4,C5orf64,C9orf85,RGMB,FRRS1L,VLDLR,CLDND1,SMARCAD1,WNK1,EMSY,PRDM2,STOX2,HPS4,RTN4,PHTF2,ADAMTSL3,MSRB3,FXR1,IFT88,NETO1" MicroRNA hsa-miR-3115:mirSVR_lowEffct hsa-miR-3115:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.13E-82 3.45E-78 2.97E-81 2.74E-80 222 971 "ACADM,SYS1,GALNT16,PSMG3-AS1,SLITRK1,ADD2,ADRA1D,BEND6,ZNF608,HACE1,CC2D2A,ALCAM,BBOX1,GOLGA7B,PARG,LGR5,MADD,TMEFF1,CADPS,NUMB,ATM,ATP1A2,SLC4A4,ATP1B3,RNF182,JAZF1,CA12,CACNA1B,CAMK2G,ISPD,INA,NEURL1,DGKI,LARGE1,SRSF11,CHM,NDST3,FADS2,NIPBL,CNR1,SLC4A8,TBPL1,MYRIP,CHD1L,SNCAIP,CSF1,DZIP3,CTH,BOC,KIF26A,DAPK1,BRINP1,SIRPA,SPOCK3,WDR20,WDPCP,HIPK3,TMTC1,MBNL2,KMT5B,GOLGA7,EIF1,VPS13B,RCAN2,GPHN,EPS8,PIPOX,CLVS1,FABP7,SCML2,CHST15,FGFR1,SUCO,IP6K2,NOP56,NSG2,GABRB3,GAD2,ARPP21,SALL3,ERAP1,CYP46A1,SPIN1,RAB30,NUDT21,GRIA2,GRID1,GYG1,ARHGAP36,HMGCL,HNRNPK,TLX1,TCEAL6,SMAP1,SOWAHA,DOCK7,IL6R,JAK1,OLFM3,KCNJ10,KCNMA1,KCNN3,STXBP5,MATN2,MBNL1,MBP,KITLG,PPM1L,POC1B,AFDN,MOBP,ERICH3,ZNF680,COL28A1,ADAM22,MYO9A,PABPC1L2A,NAP1L2,CNOT4,NPY,NOVA1,PAH,PCMT1,PDYN,NLGN3,SNX10,RETREG1,XRN1,FTO,MTRF1L,PRRX1,ING3,FAT3,CEP41,PRKCZ,MAPK10,CNNM2,NCR3LG1,PTPRE,PTPRH,CCDC40,GTDC1,RFX4,PRIMA1,KLHL11,SLC25A36,CCDC82,PNMA8A,GSTCD,TMEM100,SNX22,ACER3,ATAT1,YJEFN3,ZNF568,FAM192A,SCN2A,SCN3A,FNIP1,ELMOD1,IL17RB,KIF27,CHD9,SYBU,CTXN2,WDR37,ABLIM3,ZNF365,PPP4R3A,SLC9A5,SLC14A1,SCMH1,ATF7IP,SMARCE1,DOP1A,TRERF1,BDP1,DOK5,HECW1,UHRF1BP1L,PEG10,IQSEC2,RBM26,NKAIN2,ZSCAN29,RGL1,KLHL7,KAZN,SLC19A3,PCDHB7,PCDHB6,C18orf54,AKTIP,TIAM1,TLR4,TMPO,TPM3,TRPS1,TTTY15,TUB,ZKSCAN5,CLHC1,CLEC2L,VIPR2,TBC1D15,ZIC2,ZNF74,CELF4,REEP1,TMEM237,FTSJ1,SYNC,EMSY,HPS4,CIAPIN1,PCDH15,FAM47E,FAM13C,CERS6,VANGL2,SNX14,NETO2" MicroRNA "TGTTTAC,MIR-30C:MSigDB" "TGTTTAC,MIR-30C:MSigDB" MSigDB 9.25E-82 5.20E-78 4.46E-81 4.11E-80 166 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,DGKZ,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B1,ATP2B2,NRP2,KSR1,BSN,CACNB2,CAMK2D,SLC25A14,CARS,SLC5A11,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,CTNND2,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,MAGI2,PLPPR4,SRGAP3,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,EFNA3,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,ELAVL3,EPB41,KCNMB2,RASL12,EXTL2,AMOTL2,MEX3B,FOXG1,CAMKK2,STAG2,JPH4,IP6K3,PCDH17,TTBK1,GLDC,TNRC6A,GNAO1,EML4,TMEM121B,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,HLF,ELOVL5,DOCK7,KCNJ3,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,NCAM1,NEUROD1,NKX2-2,OMG,PDE4D,TMOD2,PIK3CD,CEP41,WBP1L,ANKHD1,PTPN13,USP47,ARID4A,PRRT2,TTLL7,RNF220,SBF1,ATXN1,SCN3A,SCN8A,ITSN1,FRMPD1,FNDC3A,FHOD3,NLGN1,SLC1A2,SLC6A9,BTBD7,SPHKAP,CPEB4,SORCS3,TMCC1,SON,ZCCHC24,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,ANO4,SATB2,WDR7,SIRT1,TLL2,RIMBP2,R3HDM1,C9orf85,TRPS1,MICAL1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,CA10,MAP3K12,STOX2,ADAMTS9,PAK5,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30B:MSigDB" "TGTTTAC,MIR-30B:MSigDB" MSigDB 9.25E-82 5.20E-78 4.46E-81 4.11E-80 166 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,DGKZ,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B1,ATP2B2,NRP2,KSR1,BSN,CACNB2,CAMK2D,SLC25A14,CARS,SLC5A11,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,CTNND2,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,MAGI2,PLPPR4,SRGAP3,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,EFNA3,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,ELAVL3,EPB41,KCNMB2,RASL12,EXTL2,AMOTL2,MEX3B,FOXG1,CAMKK2,STAG2,JPH4,IP6K3,PCDH17,TTBK1,GLDC,TNRC6A,GNAO1,EML4,TMEM121B,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,HLF,ELOVL5,DOCK7,KCNJ3,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,NCAM1,NEUROD1,NKX2-2,OMG,PDE4D,TMOD2,PIK3CD,CEP41,WBP1L,ANKHD1,PTPN13,USP47,ARID4A,PRRT2,TTLL7,RNF220,SBF1,ATXN1,SCN3A,SCN8A,ITSN1,FRMPD1,FNDC3A,FHOD3,NLGN1,SLC1A2,SLC6A9,BTBD7,SPHKAP,CPEB4,SORCS3,TMCC1,SON,ZCCHC24,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,ANO4,SATB2,WDR7,SIRT1,TLL2,RIMBP2,R3HDM1,C9orf85,TRPS1,MICAL1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,CA10,MAP3K12,STOX2,ADAMTS9,PAK5,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30E-5P:MSigDB" "TGTTTAC,MIR-30E-5P:MSigDB" MSigDB 9.25E-82 5.20E-78 4.46E-81 4.11E-80 166 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,DGKZ,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B1,ATP2B2,NRP2,KSR1,BSN,CACNB2,CAMK2D,SLC25A14,CARS,SLC5A11,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,CTNND2,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,MAGI2,PLPPR4,SRGAP3,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,EFNA3,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,ELAVL3,EPB41,KCNMB2,RASL12,EXTL2,AMOTL2,MEX3B,FOXG1,CAMKK2,STAG2,JPH4,IP6K3,PCDH17,TTBK1,GLDC,TNRC6A,GNAO1,EML4,TMEM121B,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,HLF,ELOVL5,DOCK7,KCNJ3,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,NCAM1,NEUROD1,NKX2-2,OMG,PDE4D,TMOD2,PIK3CD,CEP41,WBP1L,ANKHD1,PTPN13,USP47,ARID4A,PRRT2,TTLL7,RNF220,SBF1,ATXN1,SCN3A,SCN8A,ITSN1,FRMPD1,FNDC3A,FHOD3,NLGN1,SLC1A2,SLC6A9,BTBD7,SPHKAP,CPEB4,SORCS3,TMCC1,SON,ZCCHC24,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,ANO4,SATB2,WDR7,SIRT1,TLL2,RIMBP2,R3HDM1,C9orf85,TRPS1,MICAL1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,CA10,MAP3K12,STOX2,ADAMTS9,PAK5,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30D:MSigDB" "TGTTTAC,MIR-30D:MSigDB" MSigDB 9.25E-82 5.20E-78 4.46E-81 4.11E-80 166 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,DGKZ,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B1,ATP2B2,NRP2,KSR1,BSN,CACNB2,CAMK2D,SLC25A14,CARS,SLC5A11,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,CTNND2,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,MAGI2,PLPPR4,SRGAP3,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,EFNA3,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,ELAVL3,EPB41,KCNMB2,RASL12,EXTL2,AMOTL2,MEX3B,FOXG1,CAMKK2,STAG2,JPH4,IP6K3,PCDH17,TTBK1,GLDC,TNRC6A,GNAO1,EML4,TMEM121B,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,HLF,ELOVL5,DOCK7,KCNJ3,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,NCAM1,NEUROD1,NKX2-2,OMG,PDE4D,TMOD2,PIK3CD,CEP41,WBP1L,ANKHD1,PTPN13,USP47,ARID4A,PRRT2,TTLL7,RNF220,SBF1,ATXN1,SCN3A,SCN8A,ITSN1,FRMPD1,FNDC3A,FHOD3,NLGN1,SLC1A2,SLC6A9,BTBD7,SPHKAP,CPEB4,SORCS3,TMCC1,SON,ZCCHC24,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,ANO4,SATB2,WDR7,SIRT1,TLL2,RIMBP2,R3HDM1,C9orf85,TRPS1,MICAL1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,CA10,MAP3K12,STOX2,ADAMTS9,PAK5,PHTF2,FRMD6" MicroRNA "TGTTTAC,MIR-30A-5P:MSigDB" "TGTTTAC,MIR-30A-5P:MSigDB" MSigDB 9.25E-82 5.20E-78 4.46E-81 4.11E-80 166 543 "LRFN2,AP2A1,ZNF608,HECW2,PCDH19,TAOK1,SEMA6A,MARCH4,PCDH10,DOC2A,LRCH2,DGKZ,VAT1L,USP37,PPP4R4,TMEFF1,CADPS,ATP2A2,ATP2B1,ATP2B2,NRP2,KSR1,BSN,CACNB2,CAMK2D,SLC25A14,CARS,SLC5A11,SYNGR3,SEPT7,LGI1,LARGE1,CCPG1,CFL2,B4GALT6,NRXN3,QKI,ARHGEF6,SLC35F1,NCOR2,PLCXD3,CTNND2,FAM131B,KIAA0408,HDAC9,MATR3,KCTD8,MAML1,MAGI2,PLPPR4,SRGAP3,DMD,CPEB2,DPYSL2,EDNRA,EDNRB,EFNA3,CELSR3,FAM13A,MBNL2,ASB3,KCTD3,ELAVL3,EPB41,KCNMB2,RASL12,EXTL2,AMOTL2,MEX3B,FOXG1,CAMKK2,STAG2,JPH4,IP6K3,PCDH17,TTBK1,GLDC,TNRC6A,GNAO1,EML4,TMEM121B,RAPGEF4,GRB10,GRIA2,GRM3,GRM5,CIT,RNF165,ADAMTS6,CELF3,MAN1B1,HLF,ELOVL5,DOCK7,KCNJ3,CAMK2N2,LIFR,MAP6,MAT2A,MEIS2,NCAM1,NEUROD1,NKX2-2,OMG,PDE4D,TMOD2,PIK3CD,CEP41,WBP1L,ANKHD1,PTPN13,USP47,ARID4A,PRRT2,TTLL7,RNF220,SBF1,ATXN1,SCN3A,SCN8A,ITSN1,FRMPD1,FNDC3A,FHOD3,NLGN1,SLC1A2,SLC6A9,BTBD7,SPHKAP,CPEB4,SORCS3,TMCC1,SON,ZCCHC24,KDM3A,SP4,CDK19,LARP4,NKAIN2,NEK4,RGL1,SYPL1,CAMTA1,ADGRL3,ANO4,SATB2,WDR7,SIRT1,TLL2,RIMBP2,R3HDM1,C9orf85,TRPS1,MICAL1,TBC1D15,CLDND1,XPO1,PCDH20,MKRN3,CA10,MAP3K12,STOX2,ADAMTS9,PAK5,PHTF2,FRMD6" MicroRNA hsa-miR-129-5p:TargetScan hsa-miR-129-5p TargetScan 9.59E-82 5.39E-78 4.62E-81 4.25E-80 162 516 "ACTN1,CSMD2,NDRG3,KLHL32,ADCY5,BEND6,ANK3,PHF12,APC,LRRC4C,MARCH3,NCOA1,INSYN2B,EIF4G3,NOL4,FUBP1,CACNA1A,CACNA1B,CACNA2D1,CACNB4,CALM1,CAMK2D,CAST,RUNX1T1,CDH2,DLGAP2,CACNA2D2,GPR37L1,LHX2,KMT2C,NRXN3,NRXN1,NRXN2,CLTC,DNAJB5,NIPBL,MYRIP,NRG2,CLOCK,PLXNA4,PLCXD3,RIMS2,CCDC144A,FRMPD4,KIF26A,LIN54,MATR3,KIAA0586,KIAA0087,MFAP3L,DMD,EBF1,FAM135B,EDNRA,ELAVL3,ELAVL4,PAN3,OLIG2,PLEKHO1,EPHB1,ERBB4,ETV1,NRN1,CACNG2,DLC1,MED12L,AMOTL2,PCYOX1,C2orf88,CELF1,GABRB1,CAB39,JPH4,FAXC,GBX2,AHDC1,GFRA2,PCDH17,GHR,GLYR1,GLUL,KIAA1958,KDM2B,GPR37,RAPGEF4,GRM5,GRM7,FRMD3,BACH2,HMGB1,HNRNPK,IL6ST,KCNK1,LIMS1,FGFBP3,MBNL1,MEIS1,JAKMIP3,MXI1,NEUROD2,NFIA,NFIX,NPTX1,OPCML,PAK3,PAX6,PBX1,PCDH8,PDE4A,PDPK1,LRP12,APTX,MDGA2,PTPRZ1,OXR1,GTDC1,FIGN,ARHGEF10L,FBXW7,MAP6D1,SATB1,SCN8A,SEC14L1,ITSN1,CPEB3,RPH3A,DHX30,CCDC88A,CXXC4,MYT1L,MYCBP2,ERC1,ARHGAP26,NXT2,ADHFE1,GSE1,NSFL1C,FAM168A,ACSBG1,NUDT10,FAM208A,RPGRIP1L,PSD3,GPRIN3,FRYL,NACC2,BHLHB9,CSMD1,KAT6B,RBFOX2,NR2C2,PPIL6,FNDC5,CADM1,FAM155A,RBFOX3,KCNK12,ANKS1B,PMEPA1,HNRNPA3,GAN,JPH3" MicroRNA hsa-miR-3065-3p:mirSVR_highEffct hsa-miR-3065-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-81 6.12E-78 5.24E-81 4.83E-80 206 842 "SDE2,KCNH8,ACADM,CLK4,KLHL32,SLITRK1,SLC12A5,CDC7,PLEKHH1,RNF150,OLMALINC,MTUS1,ZNF578,SMIM17,SPOP,FAM135A,BIN1,SHTN1,ATP2A2,PROM1,MTMR2,MMD2,DDR1,KALRN,PTBP2,CAMK2G,SLC25A14,ARHGEF25,CDC27,SRSF11,SYNPR,NRXN1,FBXO7,ARMC8,SLC4A8,MFSD4A,SLC35F1,CPS1,CLOCK,CRMP1,HAPLN1,CTH,NRSN1,GAPVD1,DGKB,BRINP1,ARMCX2,ZEB2,DDX46,PLPPR4,SACS,ABI1,DTNA,ATL1,PHF20L1,KCTD3,PLEKHA1,EPB41L2,RCAN2,MTSS1L,RTN3,RCSD1,WAC,SH3YL1,MED12L,FGF13,NBEA,POMT1,SMC2,SPECC1,TRIM16,NSG1,MSANTD4,OGA,STAG2,GABRA2,DISC1,ACSS1,SESN1,PCDH17,DBF4,TNRC6A,MSL3,POLL,GNAS,GP1BB,STMN2,GRIA1,GRID1,GRIK2,ADAMTS13,NR3C1,WIF1,RASSF8,ZHX1,HRH3,ELOVL5,HMGCL,HMGCR,HNF4G,ZIC5,ZNF678,GPR62,KCNN2,VWA5A,MAT2A,MDM4,MEST,ZNF862,NCAM1,ODF2,PBX1,ETFRF1,ENPP2,BEST3,ZNF655,JAKMIP1,EXOSC10,EPB41L4B,POLR2F,PPP2R5C,PRKACB,PRKCG,PRKCZ,MASP1,VPS13C,SIDT1,CNTLN,PTHLH,CASTOR1,C1orf109,PEX5,CCDC40,RAD51D,RET,ERI2,GTDC1,RFX4,RNASEL,ELP2,RPL15,ADAL,SEMA6D,HOGA1,SMPD3,SH3GL3,CPEB3,MYO18A,NLGN1,NUBPL,SLC8A1,RAB3GAP1,SLC12A4,SLC15A2,TET1,CPEB4,MYH15,SMARCE1,SNCA,WDTC1,SOX5,BDP1,ZSWIM8,KIF1B,C11orf87,ZSCAN29,CEP68,FGD4,PRRC2C,ADAMTS17,TBCEL,ACSL6,WDR7,HIF3A,FAM200B,SIRT1,ITGB3BP,AP4E1,ARL10,TMEM9,HEY2,C5orf64,TPM1,NEIL2,TRPS1,ZMYND8,RUSC1,CLEC2L,UGT8,PLEKHH2,ZIC3,ZNF45,SLC30A3,MAP3K12,EMSY,CADM2,PARP6,TUBA1A,PCDH15,NAV3,URM1,TRIM16L,FZD3,SLC4A10,PRRT4,FAM198A" MicroRNA hsa-miR-3200:mirSVR_lowEffct hsa-miR-3200:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-81 6.21E-78 5.32E-81 4.90E-80 233 1068 "ABAT,AS3MT,C3orf14,KLHL32,KIAA1211,NLGN4X,CC2D2A,LRRC7,MRTFA,OGT,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,BCAS1,SHTN1,MIER1,NCOA1,SLC4A4,EIF4G3,ADAM23,TTLL9,ADGRB3,CFLAR,SYNJ2,NAE1,BSN,IL33,CACNA1E,CACNB2,SPAG9,CBLN1,USP2,P2RX6,AIFM1,REPS2,SOCS6,CASC2,B4GALT6,LSMEM2,EPS15L1,NRXN1,NMT2,CLTA,ARMC8,WHRN,MAGED1,CP,SLC35F1,HINFP,RGS6,SEC24C,ARHGEF10,APPL1,RUBCN,USP6NL,ECE2,DCAF8,MATR3,SPOCK2,SPATA2,JAKMIP2,SGSM2,TMCC2,GRIN3A,DMD,HS3ST4,USP3,NR1D2,DTNA,DTNB,EBF1,EDN1,EEF1A2,SYT15,APH1A,MBNL2,TMEM132E,ING4,HSD17B14,EPHB1,ANKRD13B,DENND4A,CDKL3,RRAGB,DLC1,FCGR1A,KIAA1109,FGF1,HPCAL4,CAP2,FOXF2,VTI1B,ANKFY1,EFCAB2,ARFGAP2,ST6GALNAC3,NSG1,MSANTD4,BRPF3,ARPP21,DISC1,GATM,TUBGCP4,GLDC,SPIN1,GLS,PRUNE2,DIPK1C,GPER1,GPR34,EML4,GRIA2,GRIA4,RFFL,GRM3,CLASRP,PTPN5,HNMT,IDH3B,LINC00667,ITGAM,KCNJ9,KCNJ10,KCNK2,NCOA7,PACRG,PIK3AP1,CLEC18A,MAN2A2,ZFYVE27,MARK1,MATN3,MBD1,MBNL1,SYT9,MDM4,MEIS1,MSRA,MTTP,NF1,NNAT,CLEC9A,NTRK2,IGSF11,OPHN1,OXTR,PAK3,PDE1A,PDGFRA,GPR85,PLP1,PMP2,RETREG2,CRLS1,PRKAR1B,SAMD9,PTN,OCIAD1,PTPRD,EML5,PTX3,CEP97,SH3TC2,SUSD4,RADX,GTDC1,FIGN,UBR7,C12orf49,EPHA10,KIAA0895L,MAPK12,SCN2B,PRCD,NLGN4Y,ARX,FERMT1,ST6GAL1,KANSL3,SLC9A5,SLC20A2,SLCO1A2,EPC1,SNRPN,PDZD2,MYT1L,BDP1,SPTB,SRPK2,ATP10B,CLSTN2,SSTR1,ZC4H2,ZSCAN29,DNAJC9,PLCB1,C12orf76,MTCL1,TCF7,TCF7L2,TCF12,ATP13A2,TF,AP4E1,ASXL3,R3HDM1,PDSS1,ZMYND8,HEPACAM,AMOT,SLAIN1,VIPR2,NSD2,CLDND1,RICTOR,ZIC1,ZNF708,ZNF28,ZNF138,CELF4,ZBTB38,ANKS1B,PRDM2,SLC38A1,MDH1B,MVB12B,PARP11,DOCK8,CASC15,RNF170,MSRB3,FAM198A,SPATA13" MicroRNA hsa-miR-548v:mirSVR_highEffct hsa-miR-548v:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.14E-81 6.40E-78 5.47E-81 5.04E-80 197 771 "RALGAPA1,KCNH8,ACADM,CLK4,AXIN2,TXNDC16,LRRC7,ALCAM,FAM135A,LRCH2,PKP4,ALS2,IGDCC4,ATP2B2,CDK5R1,SYNJ1,MTMR2,CALM1,PTBP2,NFS1,PRC1,ZNF501,INA,MAGI1,CFL2,CHN1,KMT2C,SULT4A1,LY86,CP,CREM,CS,SNCAIP,ARHGEF10,PDE4DIP,DZIP3,PHF14,CTNND1,TOX,KIAA0513,ZFYVE16,TM9SF4,IST1,IP6K1,JAKMIP2,ZEB2,HP1BP3,MAGI2,SPOCK3,DPP6,RCAN1,ARRDC4,DNM1L,TSPAN5,EDNRB,SEMA3D,FRY,ELAVL2,PLEKHA1,MRNIP,EPHA5,RTN3,ZNF461,KIAA1109,OLFM1,STAMBP,CGREF1,MSANTD4,GABRA1,GABRA3,ZMYND11,ZNF234,MTHFD2,MSTN,TNRC6A,ZNF638,KCNMB4,GPM6B,TDRKH,B4GALNT4,GPR17,NUDT21,GRM1,PRDM5,ZBTB49,WIF1,HMGCR,HNF4G,IGFBPL1,DHX35,SMAP1,USP54,BRINP3,CLVS2,KIT,KLC1,STMN1,NCOA7,MARK1,MEIS2,KCTD6,ZNF680,NAP1L3,NOVA1,HCN1,GLIPR1L2,PCSK1,RETREG1,GPSM2,POU3F2,MED1,KANSL1,PRKACB,PKIA,HYDIN,RELN,MDGA2,ZIK1,EML5,PTPRO,FAM66C,REV3L,RFX3,RFX4,SLC25A36,RIC8B,WLS,RTN1,RXRG,SEMA6D,SATB1,LRFN5,HOGA1,FAM19A1,COPZ1,FERMT1,NTNG1,FHOD3,SLC6A9,SLC8A1,BTBD7,IGSF9B,RIMS1,KIF13A,SNRPN,PALLD,SOX1,GLT8D1,HECW1,KDM4C,TEX2,CDK19,AJAP1,NECAB1,PLCB1,COBL,C12orf76,UNC5D,ANO4,SIN3B,TCF7L2,TCF12,SYNE1,PCDHB15,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,CRB1,ITGB3BP,TGFBR3,KCTD2,KAT6B,PITPNB,P2RY12,CLDND1,ZIC1,TRIM9,AGMO,MKRN3,TMEM198,DPYSL5,SYNC,PRDM2,STOX2,LMAN2L,CIAPIN1,PAK5,KAT6A,RSPRY1,NETO1,AP3B2,JPH3" MicroRNA hsa-miR-582-5p:PITA hsa-miR-582-5p:PITA_TOP PITA 1.27E-81 7.12E-78 6.08E-81 5.60E-80 166 544 "NDRG2,ERMN,LRRC7,ANK1,MAP4K3,APC,AQP4,TMEFF1,CAPRIN2,ZBTB10,RASL11B,ATP2B1,MTMR2,LDLRAD4,SPAG9,RUNX1T1,USP6,CD81,ZMYM4,CDO1,CCPG1,CACNA2D2,ADGRG1,SYNPR,QKI,CNN3,CNR1,SOCS5,PUM1,DOCK4,TOX,MAML1,TOMM20,PABPC5,BRINP1,ZNF804A,MFAP3L,HP1BP3,ALKBH8,SPOCK3,SRGAP3,DLG2,DMD,SLC29A4,NR1D2,CDON,APH1A,EIF4G2,TENM1,ELAVL3,EPS8,ETV1,WAC,ATP8A1,MEX3B,FOXG1,CAP2,SGIP1,STAU2,B3GAT1,OGA,NCKAP1,GATM,TNRC6A,PCDH11X,MAP7D2,FERMT2,GOLGB1,GPR34,GRID1,GRM5,KLF12,ELOVL5,HMGB1,HMGCR,HNF4G,NEGR1,INSM1,LRRTM3,KCNA1,KCNC2,MAP2,MARK1,MEIS1,MITF,ZC3H12B,NFE2L2,NOVA1,HCN1,PDE4D,GPR85,PIK3C2A,CCSER2,RETREG1,PMP22,STRN3,SCHIP1,EPB41L4B,POU3F2,PRKCZ,MAPK10,RELN,PTK2,PEX5,TMEM255A,RGS7,SLC25A36,PBRM1,ZFHX4,ZNF532,ROBO2,LGR4,SCN4B,SFPQ,ITSN1,AMBRA1,FBXO11,FAM81A,WDR47,SLC20A2,SMARCA4,MYT1L,SOX5,TSPYL2,CLASP2,SST,EPB41L3,LARP4,SS18,SULF2,ZC3H4,ABCC8,ANKRD12,CAMTA1,CAMSAP2,ADGRL3,AGTPBP1,TCF4,TCF12,WASHC4,PSD3,PUM2,FRYL,SLC44A1,RIMBP2,CSMD1,KAT6B,RBFOX2,SSBP2,FAM155A,UBE3A,SLAIN1,VAV2,ZIC1,TRIM9,ZFAND5,PMEPA1,EMSY,NAV3,FZD3,RTN4,PAK5,HNRNPA3,VANGL2,MSRB3,FRMD6" MicroRNA hsa-miR-449b:mirSVR_highEffct hsa-miR-449b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.53E-81 8.61E-78 7.35E-81 6.77E-80 211 884 "ASIC2,SYS1,KDM5D,ADD2,ADRA1D,MTUS1,GPR158,HACE1,KIAA1324,LRRC7,ALCAM,DOC2A,ANK2,ANK3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,VAT1L,TNRC6C,TMEFF1,CADPS,NCOA1,B3GALT2,DPY19L3,ADAM23,BCS1L,NRP2,SYNJ2,ARHGEF7,JAZF1,OSGIN2,WASF1,CACNB2,CALB1,KALRN,INA,DGKI,ZMYM4,EVI5L,LGI1,TIGD7,NUMBL,CHN1,EPS15L1,RAB33A,TMEM59L,SULT4A1,HECTD1,AKAP6,SLC25A27,SLC4A7,MYRIP,PREPL,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,PNPLA8,CTNND2,ZSCAN23,NOS1AP,ZFYVE16,IST1,DGKB,BRINP1,ELMSAN1,MAGI2,RHOBTB1,RCAN1,DNM1L,E2F5,SYT15,OPTN,KMT5B,RGS17,TMEM35A,C8orf37,EIF1,SPEG,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,FOXG1,PSD2,SLC37A3,NOP56,PHYHIPL,GABRA3,BRPF3,ZMYND11,ARPP21,GHDC,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,GNAS,GOLGB1,CCDC184,GPR22,PCLO,GRID1,GRM7,NXPH3,ARHGAP36,IGSF1,LRRTM3,ITPKB,KCNA2,KCND1,KCNK3,KCNN2,KIT,VWA5A,HECTD2,CLEC18A,MDM4,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,NTRK3,OPHN1,CDK18,PDGFRA,GPR85,GNG2,GDAP1L1,ST8SIA5,JAKMIP1,PURG,STRN3,ING3,PKIA,SIDT1,MTMR10,PTPRD,EML5,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,OXR1,SLC6A15,GTDC1,RIC8B,RNASEL,ZFHX4,SPIN3,ACER3,TCP11L1,LGR4,SATB1,ATXN7,LINC00461,ELMOD1,ITSN1,RUFY2,KDM4D,EFHD1,SORCS3,DMRTC1,IFT122,KIF13A,SNRPN,PALLD,PDZRN3,SON,KIF1B,CLASP2,POGZ,ARHGEF9,SYT1,CAMTA1,FAM208A,ANO4,ATMIN,SATB2,DOCK9,USP32P1,FRYL,AHCYL2,RNF216P1,LRRC8A,TNR,TPD52,TSN,TUBB1,CADM1,PLEKHH2,BCL2L13,ZNF189,SYNC,EMSY,CADM2,LMAN2L,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-449a:mirSVR_highEffct hsa-miR-449a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.53E-81 8.61E-78 7.35E-81 6.77E-80 211 884 "ASIC2,SYS1,KDM5D,ADD2,ADRA1D,MTUS1,GPR158,HACE1,KIAA1324,LRRC7,ALCAM,DOC2A,ANK2,ANK3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,VAT1L,TNRC6C,TMEFF1,CADPS,NCOA1,B3GALT2,DPY19L3,ADAM23,BCS1L,NRP2,SYNJ2,ARHGEF7,JAZF1,OSGIN2,WASF1,CACNB2,CALB1,KALRN,INA,DGKI,ZMYM4,EVI5L,LGI1,TIGD7,NUMBL,CHN1,EPS15L1,RAB33A,TMEM59L,SULT4A1,HECTD1,AKAP6,SLC25A27,SLC4A7,MYRIP,PREPL,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,PNPLA8,CTNND2,ZSCAN23,NOS1AP,ZFYVE16,IST1,DGKB,BRINP1,ELMSAN1,MAGI2,RHOBTB1,RCAN1,DNM1L,E2F5,SYT15,OPTN,KMT5B,RGS17,TMEM35A,C8orf37,EIF1,SPEG,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,FOXG1,PSD2,SLC37A3,NOP56,PHYHIPL,GABRA3,BRPF3,ZMYND11,ARPP21,GHDC,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,GNAS,GOLGB1,CCDC184,GPR22,PCLO,GRID1,GRM7,NXPH3,ARHGAP36,IGSF1,LRRTM3,ITPKB,KCNA2,KCND1,KCNK3,KCNN2,KIT,VWA5A,HECTD2,CLEC18A,MDM4,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,NTRK3,OPHN1,CDK18,PDGFRA,GPR85,GNG2,GDAP1L1,ST8SIA5,JAKMIP1,PURG,STRN3,ING3,PKIA,SIDT1,MTMR10,PTPRD,EML5,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,OXR1,SLC6A15,GTDC1,RIC8B,RNASEL,ZFHX4,SPIN3,ACER3,TCP11L1,LGR4,SATB1,ATXN7,LINC00461,ELMOD1,ITSN1,RUFY2,KDM4D,EFHD1,SORCS3,DMRTC1,IFT122,KIF13A,SNRPN,PALLD,PDZRN3,SON,KIF1B,CLASP2,POGZ,ARHGEF9,SYT1,CAMTA1,FAM208A,ANO4,ATMIN,SATB2,DOCK9,USP32P1,FRYL,AHCYL2,RNF216P1,LRRC8A,TNR,TPD52,TSN,TUBB1,CADM1,PLEKHH2,BCL2L13,ZNF189,SYNC,EMSY,CADM2,LMAN2L,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA "CTTTGTA,MIR-524:MSigDB" "CTTTGTA,MIR-524:MSigDB" MSigDB 2.08E-81 1.17E-77 9.96E-81 9.17E-80 145 409 "CPNE2,CSMD3,ADD1,UNC79,EP400,MAP4K3,FAM131A,API5,PPFIA3,MIER1,IGDCC4,MARK4,NCOA1,CCAR2,ATP2B1,ATP2B2,JAZF1,MYRF,KALRN,LRBA,CDC42,DCLK1,ARHGAP33,CDO1,CACNA2D2,FOXN3,QKI,TMEM184B,HECTD1,CNR1,ARMC8,CNRIP1,CDC42BPB,CREM,CRHBP,CRMP1,LRRC3B,CSNK1E,PPP1R16B,PUM1,DBN1,DLX1,CPEB2,DYRK1A,GOLT1B,EDN3,KLHL5,CELSR3,PHF20L1,MBNL2,EIF5,ELAVL2,EPB41,RCAN2,EPHA5,ATP8A1,PPP1R1B,SEC24B,OLFM1,UBE2E3,NBEA,CELF1,CPLX2,GBX2,SESN1,PCDH17,STARD3,GNAO1,GPM6A,GRIA2,GRID1,IL1RAPL1,ADAMTS6,HNRNPK,LRRTM3,KCNQ3,KIF5A,LAMP2,LRP1B,MEF2C,SCAMP5,MITF,MXI1,NFIA,NFIX,IGSF11,PAX6,PCDH9,PDE2A,NLGN3,ZNF655,PRRX1,PPM1B,PPP3CA,PPP5C,DIRAS2,PSD,MDGA2,PTPN13,PTPRE,PEX5,BSDC1,GTDC1,RNF220,CNTNAP3,LGR4,SOX8,ATXN2,FAM19A1,CPEB3,SLITRK3,SLC1A3,BTBD7,CPEB4,PDZRN3,USP33,SON,SOX11,SP4,LMO3,TAB2,ERBIN,VPS13A,ASTN2,FBXW11,TBL1X,TCF7L2,ARHGEF12,PUM2,ZNF106,TJP1,CBX5,DDHD1,ZFP91,HEY2,TPM3,TRPS1,MTCH1,ZIC1,SMARCAD1,CSDE1,NAV3,SLC17A6,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-146a:mirSVR_highEffct hsa-miR-146a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.27E-81 1.28E-77 1.09E-80 1.00E-79 229 1037 "KCNH8,CLK4,KIAA1211,ESYT2,ADRB2,DPY19L2P4,INTS2,RTL9,KIAA1324,CC2D2A,LRRC7,SPOP,FAM135A,AMPH,LCORL,PPFIA3,CASK,CAPRIN2,NCOA1,NUMB,B3GALT2,DCAF5,NRP2,BMPR1B,SYNJ2,JAZF1,GYG2,RAB29,LURAP1,KALRN,CANX,HIP1R,RUNX1T1,CCK,USP6,USP2,CDH10,DIS3L,CFL2,SYNPR,PPT2,ABCG2,TMEM155,ARMC8,COL4A5,ANKRD35,SLC25A27,COL9A1,BTF3L4,SLC4A8,ABI3BP,GDA,SEC24C,APPL1,PHF14,PUM1,CCDC144A,DOCK4,TOX,C8orf34,ZEB2,ZBTB24,HP1BP3,C2CD2L,DMD,USP3,NR1D2,CDON,ACOT8,DTNA,ABCC5,EDNRB,FCF1,RASGRP1,FRY,YAF2,PHF20L1,GOLGA7,KCTD3,EIF4G2,TUBD1,MRPL37,SIRPB1,CLVS1,SH3YL1,SCML2,GORAB,SLC9B2,KIAA1109,AMOTL2,FHL1,MEX3B,RGPD5,STAMBP,CAMKK2,DACH2,CSPG5,MSANTD4,SARAF,FYB1,PHYHIPL,MTHFD2,MSTN,MALT1,RUNDC3A,COPS8,SPIN1,KDM2B,TDRKH,EML4,PCLO,STMN2,GRID1,CIT,MFSD2A,CELF3,HAS2,HMGCL,ZNF181,USP54,IGSF1,ZNF385B,LRRTM3,ITPKB,KCNJ16,KCNK2,STXBP5,INSYN2,C2orf80,MARK1,SYT9,LDLRAD3,SRSF12,MID1,MMP16,SESN3,ZNF92,ZC3H12B,NOVA1,CLDN11,PDGFRA,HMGCLL1,PURG,SCHIP1,POU3F2,MED1,DIRAS2,DCHS2,BCAS3,TMEM260,STK32A,PTPRE,PID1,USP47,ZNF493,RBBP6,SLC6A15,ERI2,RIC8B,ZFHX4,ZNF532,CARF,PNMA8A,ROBO1,TMEM100,SNX22,MCMBP,ADAL,ZNF331,DGLUCY,SH3BGR,ITSN1,SH3GL2,FERMT1,ZNF365,WDR47,RAB3GAP1,CCDC88A,DMRTC1,TTC17,RIMS1,USP33,PDZD2,PEG10,DBNDD2,TAB2,PBLD,CLASP2,COLGALT2,ZC4H2,ZSCAN29,SYNE2,SYT1,ANKRD28,ANKRD12,DDHD2,CAMSAP2,ADGRL3,KLHL4,RPGRIP1L,DOCK9,SLC19A3,ARL10,DDHD1,ERCC6L2,HEY2,TPM1,RGMB,RUNDC3B,PPIL6,RFTN2,TTPA,ZKSCAN5,TUBB1,DNAJC12,PLEKHH2,ZIC1,ZNF32,TRIM9,ZNF540,GPR158-AS1,ZNF138,ZNF142,PLPPR5,CADM2,PLSCR4,SMIM8,PHTF2,FXR1" MicroRNA hsa-miR-188-3p:mirSVR_highEffct hsa-miR-188-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.77E-81 1.56E-77 1.33E-80 1.22E-79 229 1038 "KCNH8,ARID1A,AP2A2,KIAA1324,TAOK1,ALCAM,SYT13,MRTFA,OGT,MAGEE2,FAM131A,APP,MARK4,ZSCAN18,SLC4A4,ATP1B3,ZNF583,N4BP2L1,NOL4,LINC00847,DST,IL33,THSD7A,PTBP2,VXN,DGKI,CDH2,LRRFIP1,LGI1,MAGI1,CASC2,SLIT2,NRXN2,NIPBL,RAB26,COL4A5,SUMF2,IGDCC3,AKAP12,SNCAIP,CSF1,PDE4DIP,PHF14,ECE2,ZFYVE16,KCTD8,PABPC5,DBI,GIT2,ARMCX4,ZEB2,KIAA0319,ALKBH8,RABGAP1L,CHRDL1,USP3,DMTF1,ABCC9,KLHL5,PHF20L1,TNK2,TMEM35A,CALCRL,LRRC17,CDKL3,NRN1,CLVS1,CACNG2,SLC9B2,FER,FGF14,SUCO,SYNCRIP,FLT1,PSD2,UFM1,NRG3,STAG2,GAB1,ZNF44,CAB39,AHCYL1,ARPP21,ZNF559,DISC1,GFAP,ADAM28,GFRA2,GLDC,RAB30,PCDH11X,ZNF782,PCLO,GRIA2,DIDO1,GRIA4,NR3C1,PSIP1,HAS2,NXPH2,ARHGAP36,ELOVL5,MSL1,ZNF181,ZNF546,RBPJ,KCNN1,KIT,STXBP5,FGFBP3,NCOA7,MBNL1,SYT9,ZNF680,MT1M,NEXMIF,ZC3H12B,NEK1,NRCAM,HCN1,OCRL,LOC100128398,CDK18,PDE1C,PDGFRA,ABCB1,GDAP1L1,NALCN,CAMKV,ZNF655,PLCL1,PLP1,ZNF426,STRN3,IRX1,MED1,CCDC144B,PRKACB,DIRAS2,MASP1,LRRC49,SYTL2,MDGA2,PTPRD,PTPRO,C1orf109,ZNF844,ZNF493,RADX,ZYG11B,RFX4,SUGCT,EXD2,CARF,ELP2,CCDC102B,LGR4,MEG3,KCNIP1,NCBP3,ZNF331,ZFP2,ZFP30,ITSN1,NTNG1,CHD9,SLC6A8,CCDC88A,SLC22A4,ZFP1,SORCS3,CDK5RAP2,RCOR3,RIMS1,KDM4C,TEX2,KIF1B,ZNF302,ZSCAN29,NEK4,ARHGEF9,VPS13A,DDHD2,TAL1,TCEA1,ZFP90,ZEB1,RPGRIP1L,CLASP1,PCDHB6,FRYL,SIK3,DICER1,CRB1,TMPO,TPD52,TPM3,WBP2,METTL3,PRMT8,TRH,TRPC3,SSBP2,CADM1,FAM155A,AMOT,SLAIN1,PITPNB,ZNF781,ZFP37,ZNF711,LYPD6,ZNF138,SLC30A4,PRTFDC1,EVI5,XKR7,NAV3,NAV2,PPP1R3F,PDSS2,RGS7BP,DOCK8,RTN4,PHTF2,TRAM2-AS1,PIANP,SLC4A10,ZNF30" MicroRNA hsa-miR-548b-3p:mirSVR_highEffct hsa-miR-548b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.19E-81 1.79E-77 1.52E-80 1.40E-79 220 962 "PLEKHG5,SLITRK1,SLC24A4,LRRC7,BIN1,APBA2,UPRT,ALS2,CACHD1,SHTN1,CPNE5,PPP4R4,TMEM263,ARNTL,ASPH,BRINP2,ALDH4A1,ATP1B3,ATP6V1G2,BBS2,JAZF1,KALRN,VXN,CH25H,MAP7,CBR1,LDB2,CCKBR,CERS5,INA,SLC16A4,C1orf52,CDC27,ZMYM4,CDO1,SOCS6,CNOT8,QKI,SRP14-AS1,NIPBL,AKAP6,SLC4A7,ABI3BP,ACBD5,AKAP12,GDA,MICAL2,CCDC144A,RIPOR2,ZFYVE16,MATR3,IST1,PABPC5,ARMCX2,SPATA2,DCT,ZEB2,HP1BP3,FBXL5,CHRDL1,DLG2,DYNC1I1,CPEB2,RCAN1,GOLT1B,SEMA3D,EFNB3,PHF20L1,KMT5B,CALCRL,PAN3,STX2,F3,WAC,ZIC4,DLC1,FGF13,POLK,FOLH1,EFCAB2,NBEA,UFM1,CSPG5,AP4B1,GABRG2,FAM120B,ZMYND11,ZNF234,NCKAP1,CPLX2,SULT1C4,ADAM28,GLUL,ZNF638,CCDC184,GRB10,GRIA1,GRIA4,RNF165,HAS2,HMGB1,LRRC75A,RAB41,ZIC5,RBPJ,LRRTM3,KCNJ10,KIF5A,IPO5,STXBP5,STMN1,HECTD2,PIK3AP1,MAOB,MATN2,LRP1B,KITLG,MSR1,ZNF862,NAP1L3,CCDC13,NEUROD2,NFE2L2,SLC11A2,SMIM11A,IGSF11,OGG1,GPR137C,SNTG1,PAK3,PFKFB2,ZNF655,A2ML1,SNX10,EXOSC10,FAT3,POLG,PPP2R5C,MAPK9,MASP1,SNRK,TMEM260,PEX2,PID1,TMEM255A,SLC6A15,ZMAT4,DPF2,RET,FIGN,RFX4,UBR7,RIT2,SLC25A36,NUDT11,RNASEL,ROBO1,PCMTD2,RPE,UEVLD,WLS,FOXRED2,SALL1,LRRTM4,SCN7A,FAM19A1,SMPD3,ZFP2,SOX6,SH3GL2,MAGI3,SYBU,ST3GAL3,PAAF1,ZNF365,RPH3A,EPN2,WDR47,SLC6A11,KDM4D,SEPHS1,SORCS3,RCOR3,SNCA,SON,MYT1L,ENKUR,TSPYL2,RBM26,NPAS3,C11orf87,LARP4,NSFL1C,VPS13A,PLCB1,SYN2,SYPL1,ANKRD12,CAMSAP2,FAM208A,DMXL2,WASHC4,RALYL,PUM2,GPRIN3,CRB1,TMEM9,FAM124A,TNR,TRPC1,TSN,ANO5,RPL7L1,UBE2H,FAM181B,USP1,DHX33,EMSY,FAM219B,SLC4A10" MicroRNA hsa-miR-1279:mirSVR_highEffct hsa-miR-1279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.74E-81 2.10E-77 1.78E-80 1.64E-79 211 888 "SDE2,ABHD6,CSMD3,KLHL32,SLC12A5,BEND6,INTS2,HECW2,HFM1,ZFAT,MAP4K3,PPFIA2,TMEFF1,ARHGAP5,ATM,DPY19L3,ATP6V0A1,BCHE,DST,KALRN,LDB2,CCNH,LRBA,LGI1,MAGI1,TIGD7,CHM,MS4A7,DNAJB5,CNTN1,FAM149A,SLC25A27,ABI3BP,RTTN,CLOCK,ATRNL1,SLITRK5,PHF14,RIMS2,ARHGAP24,DAPK1,C8orf34,ZEB2,HEPH,DDX46,SMG7,SACS,SV2B,CPEB2,SLC12A6,ABI1,RCAN1,GOLT1B,FAM135B,HIPK3,MBNL2,EGR3,RGS17,EMX2,EPHA5,EPHB1,RTN3,ACSL4,EFEMP1,DLC1,KAT8,FGFR1,FGR,SUCO,IQCG,ANKFY1,NOP56,ZCCHC17,TACC2,SMC2,PDLIM5,STAMBP,DACH2,STAU2,ZNF512,ZMAT1,MEGF10,GABRB3,GABRG2,ILDR2,MYOZ2,SULT1C4,GPR162,TOX3,FERMT2,PRLHR,CCDC184,RAPGEF4,GRM7,ATOH8,WIF1,HPS5,ZHX1,MIER3,OPALIN,HSF2,SHISA6,HTR5A,RBPJ,PLD5,USP54,SCIN,ZNF385B,KIT,LIG4,HECTD2,MBD1,MBNL1,KCTD6,MGAT3,MIA2,WDR49,NCAM2,NEFM,NEK1,NOS1,NRCAM,NTRK3,NUCB2,GPR88,CLDN11,OXTR,GPR137C,CNTN3,PCDH9,PDGFRA,BEST3,SNX10,GPSM2,PLCL1,HMGCLL1,SCHIP1,EPB41L4B,PRKACB,MAPK9,PTCH1,PTK2,OCIAD1,ACSM5,TMEM255A,ARID4A,DBX2,RDX,GTDC1,RGS12,CARF,GSTCD,CCDC25,ATP8B4,LRRK2,LGR4,ZNF354C,LINC00461,ZFP2,NLGN1,WDR37,SLC1A3,SLCO1A2,CPEB4,SMARCE1,KDM4C,ZC3H13,TAB2,SSTR2,SEPT8,DIP2A,SEPT3,SYT11,NUDT10,PLCB1,SYT1,TAC1,ADGRL3,ANO4,RPGRIP1L,TCF12,PCDHGB7,DOCK9,PCDHB6,TEX15,ZFPM2,AKTIP,DDHD1,FAM124A,PIK3R5,TPD52,TPM1,METTL3,RFTN2,OSBP2,ETNPPL,ZNF711,KCNT2,ZNF45,LYPD6,ZNF177,FSTL5,EML6,EMSY,STMN4,PCDH15,SLC17A7,CASC15,JMJD1C,RNF170,FXR1" MicroRNA hsa-miR-383:mirSVR_highEffct hsa-miR-383:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.88E-81 2.18E-77 1.85E-80 1.71E-79 231 1057 "SERPINA3,SDE2,AS3MT,GALNT13,ADD3,PWWP2A,ADORA3,MTUS1,KCTD16,KIAA1324,CC2D2A,GOLGA7B,FAM135A,AMPD3,PARG,MIER1,ASPH,ZBTB10,NUMB,ATP2B3,BARD1,SEC11C,CAMK2D,VSTM2A,CBLN1,ZNF501,SHISA7,ZMYM4,CDH18,LARGE1,RCBTB2,MS4A7,SYNPR,TJP2,AKAP7,AKAP6,RBM39,AKAP12,PHACTR3,CNTNAP2,PHF14,GREB1,RIMS2,PPP6R2,CX3CR1,HDAC9,PABPC5,ELMSAN1,MYEF2,HP1BP3,FBXL5,SV2B,DMTF1,DTNA,EBF1,EDN1,EDNRA,YAF2,EGFR,TENM1,ELN,CALCRL,PAN3,ENO2,VPS13B,EPHA5,GPHN,RPS6KC1,TUBB4A,TAOK3,FGF13,POLK,MEX3B,SEMA4D,CSPG5,STAU2,SARAF,ABLIM2,OGA,GABRA2,BRPF3,FAM120B,NCKAP1,DISC1,PCDH17,RAB30,GLS,TOX3,GNAO1,GPD2,PRUNE2,GRIA4,RNF165,MFSD2A,FAM222A,UBE2QL1,VSIG4,HMGB1,HTR2A,NKD1,ZIC5,IGSF1,IL11RA,IL12A,KCNC1,KCNJ3,KCNJ10,KCNK1,KCNK2,CREG2,IPO5,LIMS1,ZNF667-AS1,LOC100128239,MARK3,MEST,POC1B,AFDN,WDR49,ZNF680,NELL2,NEUROD1,NNAT,CNOT4,NOVA1,DNHD1,NUCB2,CLDN11,CNTN3,CDK18,SLC10A4,NOMO2,FAM218A,A2ML1,RETREG1,SMOX,PLP1,ASPDH,MAPKAP1,STRN3,EPB41L4B,SLC36A4,NXPH1,SH3KBP1,PPM1B,PRKCZ,SYTL2,PLPPR1,TMEM260,ZSCAN2,RAD52,SUSD4,RDX,SLC6A15,UBR7,RNASEL,RPRD1A,CARF,RPE,SNX22,TCP11L1,LGR4,SALL1,LRFN5,HOGA1,ELMOD1,NLGN4Y,NTNG1,SHMT2,AMBRA1,FNDC3A,ST3GAL3,FAM81A,SLC9A5,SPHKAP,CMTR2,SON,SOX5,SP4,KDM4C,IDI2-AS1,PEG10,RBM26,SPART,C11orf87,CLASP2,CLSTN2,RGL1,KLHL7,ANKRD28,ROBO3,ADGRL3,AGTPBP1,KLHL4,TPCN2,SYNE1,FRYL,SIK3,CYB561A3,SIRT1,CRB1,ITGB3BP,TMOD1,PRRT1,TPD52,WBP2,STXBP4,ZMYND8,PPIL6,ANKRD20A2,FAM155A,MEAF6,WNT7A,SLC13A3,XRCC4,TRIM9,ZFP41,TCEAL7,ZXDA,EMSY,PRDM10,TUBA1A,ADAMTS9,SLC17A7,KCNAB1,EPM2A,RGS7BP,FZD3,RNF146,SLC4A10,FAM198A" MicroRNA hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA_TOP PITA 3.92E-81 2.20E-77 1.87E-80 1.72E-79 157 487 "ACTN1,XKR4,SLC25A25,KLHL32,ELFN2,ADD3,ESYT2,ZNF608,PCDH19,TAOK1,SPOP,ANK3,APC,ZBTB10,NCOA1,EIF4G3,CADM3,BCHE,BCL7A,BTRC,CACNB4,CALM1,MAP7,RUNX1T1,TMEM257,DLGAP2,FOXN3,LHX2,KMT2C,NRXN2,CLTC,DNAJB5,QKI,NIPBL,CNN3,AKAP5,NRG2,ZNF385A,LRIG1,CTNND1,RIMS2,GAPVD1,ARHGAP24,FRMPD4,TOX,KIF26A,MATR3,ZEB2,MFAP3L,CEP170,ZC3H11A,SPOCK3,ABI1,ABCC5,KLHL5,YAF2,EGR3,OLIG2,EPHB1,ETV1,NRN1,CACNG2,ACSL4,TAOK3,MED12L,AMOTL2,MEGF11,CAB39,AHDC1,PCDH17,GK,TMEM121B,GRM7,RNF165,BACH2,MIER3,HMGB1,HNRNPK,IGF1,C5orf24,RBPJ,LIFR,MAP2,MBNL1,LRP1B,MEIS1,MEIS2,SESN3,MXI1,MYO5A,NEXMIF,NEUROD2,NFIX,OCRL,OPCML,PCSK2,PDPK1,PIK3R1,PDZRN4,LRP12,MINDY2,PTN,PTPRZ1,USP47,OXR1,ARID4A,ZMAT4,FIGN,ARHGEF10L,FBXW7,KCNIP3,SCN8A,FNIP1,TRA2B,ITSN1,CPEB3,SLC1A2,CCDC88A,TET1,SNCA,MYT1L,SOX2,SOX11,SP4,ENKUR,MYCBP2,NKAIN2,GSE1,VAMP1,SYT1,CAMTA1,UNC5D,ADGRL3,TCF4,RPGRIP1L,PSD3,GPRIN3,ZNF106,LRRC8A,KAT6B,NR2C2,FNDC5,SGK3,CADM1,FAM155A,SLAIN1,PITPNB,FLRT2,ZIC2,CELF4,ANKS1B,SYNC,PMEPA1,STOX2,SLC17A6,PAK5,HNRNPA3" MicroRNA hsa-miR-892a:mirSVR_highEffct hsa-miR-892a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.93E-81 2.21E-77 1.87E-80 1.72E-79 220 963 "RALGAPA1,XKR4,NDRG3,ADCY2,ERMN,PTCHD1,NLGN4X,HECW2,PPFIA1,PKP4,SHTN1,MIER1,TMEM108,SLC4A4,ADGRB3,BARD1,ARHGEF7,CACNA1E,KALRN,HIP1R,RHBDL1,ARHGEF25,ZNF501,P2RX6,SEPT7,EVI5L,TIGD7,CLGN,QKI,SRP14-AS1,TMEM155,BTF3L4,ACBD5,CLOCK,C2CD2,RBM39,HAPLN1,ARHGEF10,VCAN,SLITRK5,PHF14,CTNND2,HDAC9,LONRF1,ZEB2,CEP170,MAGI2,LYPD1,DDX46,SRGAP3,USP3,DYNC1I1,DMTF1,DYRK1A,ABCC9,EDNRB,FCF1,EFNB3,KMT5B,GOLGA7,ING4,KCNMB2,NRN1,ZIC4,KIAA1109,MEX3B,FOXG1,CAP2,SLC37A3,NOP56,DACH2,GALNT15,MSTN,AHDC1,GLI2,GLRB,TNRC6A,ZNF638,GPT2,PSRC1,FUT10,ATP2B1-AS1,GRIK1,GRIK2,NR3C1,MAP4K5,FRMD5,ACOT7,HMGCR,HNMT,IGFBP1,PLD5,SCIN,IL6ST,IBA57,LRRTM3,KCNA6,KCNMA1,HECTD2,MBNL1,MDM4,MKLN1,MOBP,NAP1L3,NF1,VWA2,NPTX1,NTRK2,GPR88,GLIPR1L2,PCDH8,PDCD2,PDE1C,PDGFRA,GPR85,CYTL1,NLGN3,FAM218A,ANKRD16,PSAT1,SPATA6,LRRN3,PRKACB,PKIA,PKN2,DIRAS2,RELN,SYTL2,PLPPR1,EML5,PTPRG,C1orf109,CEP97,TMEM255A,RDX,RET,REV3L,GTDC1,RFX3,RGS3,RGS4,RGS7,SETD5,CNTNAP3,NCBP3,TRAPPC13,SATB1,CSRNP3,ATXN2,SUPT20H,NLGN4Y,SH3GL2,DOCK10,NTNG1,SHC4,CHD9,FHOD3,R3HDM2,SLA,ZNF365,PREX2,SLC8A3,CCDC88A,SLC15A2,TET1,CPEB4,RCOR3,LIMCH1,PALLD,MYO16,SOX5,SP4,SRPK2,KANK1,FNDC9,MTCL1,TAF9,UNC5D,TBCEL,KLHL4,TBX15,ATMIN,TCEA1,ZEB1,TCF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,PMS2CL,MTMR14,TMPO,TPM1,MEAF6,BEST1,CLIP2,NSD2,XPO1,XRCC4,ZNF711,KCNT2,REEP1,FSTL5,ANKS1B,SYNC,EMSY,LRP8,NAV3,WNK3,PLSCR4,GOPC,FAM13C,KAT6A,ADAMTSL3,CPNE4" MicroRNA hsa-miR-186-5p:TargetScan hsa-miR-186-5p TargetScan 4.84E-81 2.72E-77 2.30E-80 2.12E-79 185 685 "CLK4,NCKAP5,NDRG3,ADCY5,PTCHD1,INTS2,KCTD16,OSBPL8,C1QTNF3,BCAR3,CDC42BPA,ANK3,MAP4K3,PARG,CNTNAP1,APBB2,MIER1,KIAA1614,CASK,ARHGAP5,CADPS,BRINP2,ATP1A2,BACH1,CDK5R1,MTMR3,BTRC,FOXK1,CALB1,CAST,MAP7,RUNX1T1,CDC42,NOG,ARHGAP22,QKI,FHL5,ARMC8,LETMD1,AKAP5,NRG2,SEC31B,OSBPL3,CNTNAP2,RIMS2,CCDC144A,PYGO1,KIAA0408,KIAA0087,MFAP3L,GRIN3A,DMD,CPEB2,PDCD6IP,ATL1,FAM13A,ABI2,EIF5,PAN3,MTSS1L,DNAJC27,CACNG2,EFEMP1,DLC1,FECH,MEX3B,KHDRBS3,NSG2,CELF1,FUT9,GABRA4,ATP8A2,GFRA1,PCDH17,GPR12,GPR37,RAPGEF4,GRIA2,PARD3B,KIF3A,FICD,CELF3,HAS2,KLF12,HMGB1,HNMT,NEGR1,AGFG1,IRF8,RAB41,IGF1,KNDC1,INSM1,LRRTM3,METTL21A,KCNB1,CLVS2,KLHL23,CREG2,IPO5,LAMP2,MAP2,CHIC1,MITF,AFF1,CCDC80,MDGA1,MXI1,MYT1,NASP,HCN1,DDR2,IGSF11,PAK3,PBX1,PCSK1,PDE3A,PDE3B,PDE4D,GPR85,CDK14,NLE1,FAM216A,FTO,LRP12,NXPH1,PPM1B,CEP41,DIRAS2,APTX,PID1,ERI2,GTDC1,FIGN,KLHL11,RORB,ELP2,HUNK,SALL1,SATB1,ATXN7,SCN2A,SCAF8,ASAP3,CPEB3,CHD9,FNDC3A,BTBD3,EPN2,EPC1,MBD5,FAM126B,MYT1L,PEG10,ARHGAP26,RBM26,LMO3,CLSTN2,FAM168A,ACSBG1,NECAB1,ANKRD28,ANKRD12,KAZN,PSD3,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,RBFOX2,CADM1,PMEPA1,CADM2,CAB39L,FZD3,RNF170,MSRB3,FXR1,JPH3" MicroRNA hsa-miR-148b-3p:TargetScan hsa-miR-148b-3p TargetScan 6.29E-81 3.53E-77 2.99E-80 2.75E-79 170 577 "ACHE,ADCY2,CCDC85A,GRAMD1B,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,PPFIA2,MIER1,CDK13,MARCH3,ASPH,NCOA1,ATP2A2,MTMR9,NOL4,BCL2L2,BCL7A,CDK5R1,FUBP1,CABP7,CAMK2A,CANX,CAST,RUNX1T1,FMNL3,CERS5,CDC25B,NOG,CFL2,B4GALT6,CHRNB2,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,FEZ2,CCDC144A,GAPVD1,ELMO1,DLG2,RAB39B,DMPK,DYRK1A,EDNRA,HIPK3,KLHL5,EGFR,EGR3,ELAVL2,ELAVL4,PAN3,EMX2,EPB41L1,MTSS1L,ETV1,F3,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,FUT9,NEURL4,GABRA1,NCKAP1,GAP43,ARFIP1,AHDC1,PPARGC1A,KDM2B,GPM6A,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,C5orf24,IL6ST,CDH20,KCND3,KCNH1,CLVS2,KCNN3,KIT,IPO5,NAT8L,AQP11,MDM4,MITF,MPP2,ADAM22,MYO9A,NAP1L1,NCAM1,NDP,NEUROD1,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,CDK14,PIK3C2A,POU3F2,MED1,PPP2R5E,KANSL1,CNNM2,MDGA2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,SCN8A,MRAS,HSPA4L,PPP1R9A,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,ATP11A,CAMSAP2,NSD1,ARHGEF12,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,RBFOX2,CADM1,BCL2L13,BEST1,KLC2,RICTOR,EML6,DPYSL5,LRP8,RGMA,RTN4,CERS6,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-148a-3p:TargetScan hsa-miR-148a-3p TargetScan 6.29E-81 3.53E-77 2.99E-80 2.75E-79 170 577 "ACHE,ADCY2,CCDC85A,GRAMD1B,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,PPFIA2,MIER1,CDK13,MARCH3,ASPH,NCOA1,ATP2A2,MTMR9,NOL4,BCL2L2,BCL7A,CDK5R1,FUBP1,CABP7,CAMK2A,CANX,CAST,RUNX1T1,FMNL3,CERS5,CDC25B,NOG,CFL2,B4GALT6,CHRNB2,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,FEZ2,CCDC144A,GAPVD1,ELMO1,DLG2,RAB39B,DMPK,DYRK1A,EDNRA,HIPK3,KLHL5,EGFR,EGR3,ELAVL2,ELAVL4,PAN3,EMX2,EPB41L1,MTSS1L,ETV1,F3,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,FUT9,NEURL4,GABRA1,NCKAP1,GAP43,ARFIP1,AHDC1,PPARGC1A,KDM2B,GPM6A,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,C5orf24,IL6ST,CDH20,KCND3,KCNH1,CLVS2,KCNN3,KIT,IPO5,NAT8L,AQP11,MDM4,MITF,MPP2,ADAM22,MYO9A,NAP1L1,NCAM1,NDP,NEUROD1,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,CDK14,PIK3C2A,POU3F2,MED1,PPP2R5E,KANSL1,CNNM2,MDGA2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,SCN8A,MRAS,HSPA4L,PPP1R9A,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,ATP11A,CAMSAP2,NSD1,ARHGEF12,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,RBFOX2,CADM1,BCL2L13,BEST1,KLC2,RICTOR,EML6,DPYSL5,LRP8,RGMA,RTN4,CERS6,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-152-3p:TargetScan hsa-miR-152-3p TargetScan 6.29E-81 3.53E-77 2.99E-80 2.75E-79 170 577 "ACHE,ADCY2,CCDC85A,GRAMD1B,HECW2,ALCAM,ARHGAP20,PITPNM2,LRFN1,ANK2,PPFIA2,MIER1,CDK13,MARCH3,ASPH,NCOA1,ATP2A2,MTMR9,NOL4,BCL2L2,BCL7A,CDK5R1,FUBP1,CABP7,CAMK2A,CANX,CAST,RUNX1T1,FMNL3,CERS5,CDC25B,NOG,CFL2,B4GALT6,CHRNB2,PLAA,CLCN3,QKI,CNR1,PCYT1B,CLOCK,NCOR1,CS,CSF1,FEZ2,CCDC144A,GAPVD1,ELMO1,DLG2,RAB39B,DMPK,DYRK1A,EDNRA,HIPK3,KLHL5,EGFR,EGR3,ELAVL2,ELAVL4,PAN3,EMX2,EPB41L1,MTSS1L,ETV1,F3,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,FUT9,NEURL4,GABRA1,NCKAP1,GAP43,ARFIP1,AHDC1,PPARGC1A,KDM2B,GPM6A,KAT7,RASSF8,BACH2,HLF,AGFG1,IGF1,C5orf24,IL6ST,CDH20,KCND3,KCNH1,CLVS2,KCNN3,KIT,IPO5,NAT8L,AQP11,MDM4,MITF,MPP2,ADAM22,MYO9A,NAP1L1,NCAM1,NDP,NEUROD1,NFIX,NFYA,NOVA1,NOVA2,NPTX1,GPR137C,PDE4B,PDE4D,CDK14,PIK3C2A,POU3F2,MED1,PPP2R5E,KANSL1,CNNM2,MDGA2,PIGG,MTMR10,PTPRD,FAM184A,FIGN,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,SCN8A,MRAS,HSPA4L,PPP1R9A,CHD9,FBXO11,FAM81A,BTBD3,EPN2,CPEB4,CDK19,MMS19,ATP11A,CAMSAP2,NSD1,ARHGEF12,FRYL,DICER1,AP4E1,MTMR14,CBX5,NR2E1,RBFOX2,CADM1,BCL2L13,BEST1,KLC2,RICTOR,EML6,DPYSL5,LRP8,RGMA,RTN4,CERS6,JMJD1C,FXR1,JPH3" MicroRNA hsa-miR-655-3p:TargetScan hsa-miR-655-3p TargetScan 7.52E-81 4.23E-77 3.57E-80 3.29E-79 174 606 "DPF1,ACLY,ADCY5,CCDC85A,ADD1,ADD3,ESYT2,AP2A1,HECW2,CASKIN1,PCDH19,MARCH4,LRCH2,ANK2,APBB2,APC,EPB41L5,GAS7,APP,AQP4,ASCL1,CAPRIN2,NCOA1,ATP2A2,B3GALT2,BCL2L2,DCAF5,KSR1,CALM1,CANX,RUNX1T1,CDC42,CDH2,DCLK1,NUMBL,CHN2,NIPBL,CNR1,HAPLN1,FEZ2,PLCXD3,HDAC9,MATR3,PITPNC1,JAKMIP2,MAGI2,RABGAP1L,DMD,CPEB2,RCAN1,DYRK1A,ABCC9,EBF1,HIPK3,OPTN,ABI2,C8orf37,EN2,EPB41,EPB41L2,MTSS1L,DENND4A,ETV1,RTN3,PCYOX1,APOPT1,GAB1,CHL1,NCKAP1,GPR162,AHDC1,GFRA2,PCDH11X,FERMT2,GPD2,CECR2,GRIA1,GRM3,FAM19A2,IL1RAPL1,PSIP1,RASSF8,HPSE2,HMGCR,AGFG1,RBPJ,KCNJ3,IPO5,KTN1,LSAMP,MAP4,AQP11,LRP1B,MEIS1,MID1,MITF,MMP16,MYO9A,NF1,NFIA,NFYA,NOVA2,HCN1,DDR2,OPA1,PAX6,PDE3B,PDE4A,PDGFRA,CDK14,PIK3C2A,PIK3R1,FAM216A,CEP41,DIRAS2,PROX1,ANKHD1,ELOVL2,PTPRG,PTX3,RAB5B,RBBP6,KHDRBS2,RDX,GTDC1,RFX3,RFX4,RGS7,RPRD1A,RPL38,SATB1,CSRNP3,ATXN1,FNIP1,CPEB3,MBD5,PEG10,CDK19,CLSTN2,NKAIN2,MPRIP,PRRC2C,ANKRD28,CAMTA1,ATMIN,SATB2,DOCK9,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AHCYL2,FBXL16,CBX5,DDHD1,HEY2,LRRC8A,CSMD1,RBFOX2,NR2C2,HEPACAM,REEP1,DPYSL5,ANKS1B,PMEPA1,CADM2,RGS7BP,GOPC,CERS6,PIANP" MicroRNA hsa-miR-149*:mirSVR_highEffct hsa-miR-149*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.78E-81 4.93E-77 4.16E-80 3.83E-79 218 950 "VWA5B2,SYN3,ASIC1,EMILIN3,FAM43B,CSMD3,ADAR,SORCS1,AP2A1,MTUS1,CARNS1,AMPH,LRFN1,SUGT1P4-STRA6LP-CCDC180,GPAM,VAT1L,BCAS1,API5,SEMA4G,CDK13,BRINP2,EIF4G3,ATP6V1G2,NRP2,PROM1,SYNJ1,ARHGEF7,GPC2,CA8,CLDN10,CPNE6,PPT2,TPP1,NIPBL,CNTFR,AKAP6,WHRN,BTF3L4,GAL3ST1,MROH8,CSF1,CSF1R,CSF2RA,MICAL2,NCAN,CST3,DCAF4,BOC,FGFR1OP2,KATNAL2,ZNF337,COPS7A,C2CD2L,NTM,KIF19,DLG4,ACOT8,DTNA,DNAJB6,DYRK1A,EDNRA,CNNM1,EIF4G2,EPHB1,RABEPK,DENND4A,SPEG,GMPR2,ZSCAN30,FGF11,FGFR1,FOXG1,IP6K2,AGAP2,SPECC1,PHYHIPL,GAD1,FAM120B,JPH4,DISC1,ATP8A2,AHDC1,GLYR1,AIFM3,LOXL3,GNAS,FUT10,CCDC184,GRID1,RFFL,SERP2,GRM1,CIT,KAT7,ATOH8,PADI2,FRMD5,ATXN2L,HPSE2,AGBL5,DHX35,LRRC75A,KIF5A,KLRC3,HECTD2,MAP6,SYT9,CD200,COL28A1,ADAM22,BCO1,MT3,NEK1,NF1,NHLH1,NRGN,SETD4,ZDHHC22,DPY19L2P2,CDK18,PDE1B,GDAP1L1,A2ML1,SMOX,PMP22,SPATA6,PRKCG,PTK2,PTPRG,PTPRN,TMEM145,ZSCAN2,RAB5B,FAM66C,FEZF2,ERI2,MORC4,GTDC1,RGR,RGS12,RNASEL,GLDN,RPS6KA2,ATAT1,KCNIP2,KCNIP1,NCBP3,HOGA1,FNIP1,SEC14L1,FERMT1,SYBU,ZNF365,SLC2A5,LIMS2,KANSL3,PKNOX2,KDM4D,SLC11A1,KBTBD4,SLC12A4,TMEM132D,ZNF667,SMARCD3,IFT122,MYO16,UNC80,TNIK,KIF21B,KDM3A,DBNDD2,NFASC,COLGALT2,LRRC4,STAU1,TTBK2,STAC2,SULF2,GANAB,STXBP1,SUPT5H,VAMP1,SYN1,SYN2,SYP,SEMA4A,ANO4,TBX15,ZFP90,TCF7L2,SYNE1,TNS2,TIAM1,ACTR6,FAM124A,METTL3,RUNDC3B,RUSC1,KCNE5,SSBP2,ZKSCAN5,GORASP1,FAM181B,CCDC136,VLDLR,BEST1,NSD2,MEIS3,PRDM2,LRP8,CSDE1,STOX2,NAV3,CAB39L,PDSS2,PAK5,NUP214,AP3B2" MicroRNA hsa-miR-142-3p:mirSVR_highEffct hsa-miR-142-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.25E-80 7.02E-77 5.91E-80 5.45E-79 196 773 "CPNE2,KCNH8,FMNL2,MTUS1,OSBPL8,TAOK1,CEP126,LTBP4,ANK3,EP400,MAP4K3,USP28,APC,ZFYVE28,ARNTL,INSYN2B,ATP1A2,ATP2A2,DPY19L3,BACH1,PROM1,RAB29,CACNA1D,CACNA1E,L3MBTL4,CFL2,CHM,CLTA,TMEM184B,SRP14-AS1,HECTD1,AKAP6,SLC25A27,MYRIP,CP,FEZ2,LRRC3B,ARHGEF10,PUM1,USP6NL,GAPVD1,ZFYVE16,EARS2,BRINP1,ZEB2,COPS7A,CCDC3,DLG2,USP3,NR1D2,CPEB2,DMTF1,DPYSL2,ECM2,E2F5,WDPCP,ANKRD46,CNNM1,SEMA3D,CALCRL,RCAN2,CEP85L,ECSIT,ACSL4,CEP78,SUCO,FOXF2,FLNC,SLC37A3,HVCN1,ST6GALNAC3,FYB1,PHYHIPL,ACSS1,GHR,HPGDS,OS9,GNAS,PSRC1,PRLHR,EML4,DIDO1,GRIA4,GRM7,RNF165,KAT7,BVES,PSIP1,VSIG4,HMGB1,TLX1,ZDHHC15,FAM95B1,C5orf24,LRRCC1,IL6ST,ITGAV,ITPKB,KCNN2,HECTD2,LRP1B,SRSF12,MGAT3,MMP16,MYO7A,P2RY13,NCAM2,NF1,SLC11A2,GPR137C,PAX6,PCSK1,PDE4B,ABCB1,FAM218A,A2ML1,ZFYVE21,STRN3,RC3H2,PRKAB2,RAB39A,RAB3A,ATG16L1,OXR1,ZYG11B,FIGN,RGS3,NUDT11,EXD2,ELP2,PCMTD2,RPE,LRRK2,CNTNAP3,LGR4,SEMA6D,SCN2A,SCN8A,SUPT20H,SCAF8,SGK1,NTNG1,FNDC3A,SLC1A3,CCDC88A,ELMO2,BTBD7,ATF7IP,RIMS1,MBD5,USP33,DOP1A,SOX5,TSNAXIP1,KDM4C,TEX2,MCF2L2,SPART,TAB2,NKAIN2,STAU1,DIP2A,NSFL1C,FGD4,PLCB1,SYN2,SYPL1,MTCL1,ADGRL3,DMXL2,ZFP90,OBSL1,BHLHB9,ERCC6L2,C5orf64,TPM1,PRMT8,RUNDC3B,TSC1,UGT8,MTCH1,BEST1,NSD2,RICTOR,SLC13A3,XPO1,ZIC3,TRIM9,MKRN3,STOX2,NAV3,PDSS2,PAK5,FBXO36,SSPN,KLHDC1" MicroRNA hsa-miR-140-5p:mirSVR_highEffct hsa-miR-140-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.28E-80 7.19E-77 6.05E-80 5.57E-79 208 869 "CSMD3,GALNT16,SORCS1,ZNF608,INTS2,OSBPL6,SPARCL1,CEP126,LTBP4,OGT,DPP10,ANK2,MAGEE2,LGR5,MIER1,PPP4R4,CADPS,NCOA1,TTLL9,BACH1,SEC11C,WASF1,CA4,CALB1,THSD7A,CAST,INA,DGKI,LRBA,ZMYM4,UBE2L6,CNOT8,KMT2C,NMT2,CNTN1,SLC4A8,BAG4,CP,RBM39,GDA,SNCAIP,CSNK1E,OSBPL3,CSNK1G3,PDE4DIP,ERC2,PNPLA8,CYBB,DGKB,DAPK1,CEP170,DDX46,DYNC1I1,DMTF1,DPYSL2,MAMLD1,ABCC9,KLHL5,SUGP2,AASS,EIF4G2,ELAVL2,CERCAM,EPB41L2,RABEPK,CHST15,KIAA1109,POLK,VTI1B,ANKFY1,JKAMP,CELF1,STAU2,FYB1,DKK3,GABRA2,GALC,RAPGEF6,NCKAP1,C15orf41,INPP5K,LRRC37A6P,SRCAP,TCERG1,MSL3,PCDH11X,KDM2B,PSRC1,GPM6A,PRLHR,FAM19A2,CELF3,C1orf94,HMGCL,HNF4G,ZDHHC15,SMAP1,DIPK1A,KCNN2,KLC1,TTYH2,LAMP2,HECTD2,MAN2A2,MAP4,MARK1,MBD1,GIT1,CTNNA3,MYO6,MYO9A,NEUROD2,NFE2L2,NUCB2,TBC1D25,ZNF827,PAK3,CDK14,A2ML1,STRN3,ING3,EPB41L4B,DRAM2,CEP41,PKIA,PKN2,MAPK9,PRODH,PROX1,SNRK,BDNF-AS,TMEM260,PTPRO,RBBP6,SLC6A15,TRIM68,RFX3,RIC8B,NUDT11,CARF,NEK11,MEG3,ATAT1,RTKN,RTN1,RYR3,AP1AR,AMER2,SCN8A,LINC00461,FNIP1,ELMOD1,SUPT20H,HSPA4L,SGK1,SH3GL3,ASAP3,SHC4,NLGN1,ZNF365,SMARCC2,SNRPN,SOX1,MYCBP2,ATP10B,STOX1,STX1A,ANKRD28,ANKRD12,DDHD2,TAL1,ADGRL3,SATB2,ZEB1,TRIM2,PCDHB9,PCDHB4,DNAH7,GPR161,HEY1,TLR4,HEY2,R3HDM1,SEZ6L,NPL,RGMB,PRMT8,AMACR,TRPC3,FNDC5,RUSC1,TSC1,ZKSCAN5,SLC35A4,UGT8,SLAIN1,MEAF6,VLDLR,LAT2,SLC47A2,ZIC3,ZNF540,ANKS1B,LAMP5,NAV3,WNK2,RNF170,FXR1" MicroRNA hsa-miR-552:mirSVR_highEffct hsa-miR-552:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-80 1.00E-76 8.44E-80 7.77E-79 202 822 "NBAT1,SORCS1,ADORA3,KIAA1324,PCDH10,BBOX1,FAM135A,PHF12,PKP4,API5,SEMA4G,RGS20,CADPS,LINC00173,TTLL9,CFLAR,DST,CACNA1D,CAST,CBR1,CCNH,USP6,DGKI,LRBA,CLGN,NIPBL,BTF3L4,LETMD1,TRIM69,CS,DCAF4,EDRF1,DCC,C8orf34,ZEB2,HP1BP3,CEP170,BLOC1S6,RHOBTB1,KIF19,EXOG,USP3,MAMLD1,FRY,MBNL2,EMX2,MFSD10,ANKMY1,ADGRV1,SCML2,FKTN,PPP1R1B,FER,MED12L,POLR1B,FGF12,SMC2,USP21,NPTN,NSG2,CELF1,CGREF1,NSG1,TVP23A,GABRA2,GABRA3,ZNF44,GABRB1,NEK6,SULT1C4,ARFIP1,CYP46A1,RUNDC3A,INSM2,FUT10,RAPGEF4,GRIN2C,GRM2,ZBTB49,SOX21,RASSF8,TNFAIP8L3,LINC01102,HPSE2,HNRNPK,TCEAL6,IGFBP1,IL6ST,NME9,ITGA7,JAK1,LAMP2,ARHGAP12,ASPRV1,MATN3,MEIS1,MOG,SCG3,NEK1,NELL2,NF1,NOVA1,DNHD1,NPPA,NUCB2,ODF2,OPHN1,ETFRF1,PDE1A,PDGFRA,GPR173,PRIMPOL,SPATA6,PACSIN1,NXPH1,POU3F2,DRAM2,TATDN3,PTPA,PPP3CB,PRKAR1B,PRKCZ,MAPK10,KLK6,PLPPR1,PTN,OCIAD1,PTPRE,RAD52,RASGRF1,VEPH1,KHDRBS2,RGS3,MRAP2,MCMBP,SEMA6D,SGK1,FERMT1,FNDC3A,ST6GAL1,NLGN1,SLC8A3,SLC15A2,BTBD7,ATF7IP,MBD5,MYO16,UNC80,PDZD2,KDM3A,MYCBP2,MPRIP,ADHFE1,GANAB,SUPT5H,SYPL1,COBL,MTCL1,DNMBP,SIN3B,ZEB1,RPGRIP1L,WDR7,SYNE1,DOCK9,PCDHAC2,USP32P1,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,FBXL16,TIAM1,R3HDM1,C9orf85,PRMT8,ELP5,AMACR,TRO,PPIL6,RUSC1,ZKSCAN5,UGT8,VLDLR,XPO1,ZBTB14,ZNF74,ZNF225,STOX2,PCDH15,PPP1R3F,FIP1L1,PCBP4,WIPF2,WNK2,KLHDC1,IFT88,RNF146" MicroRNA hsa-miR-198:mirSVR_highEffct hsa-miR-198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-80 1.26E-76 1.06E-79 9.75E-79 203 831 "SORCS1,FAM135A,AMPD2,OGT,LCORL,USP28,CNIH2,PPFIA1,AQP4,CDK13,CAPRIN2,ATP1A3,ALDH7A1,ADAM15,BACH1,ADGRB3,CASTOR3,JAZF1,C5,GPC2,OSGIN2,CACNB2,SYT6,CAST,SPAG9,NFS1,CBS,LDB2,INA,TMEM257,ENTPD6,CDC42,L3MBTL4,CHGA,JAM2,NRXN1,QKI,TMEM184B,FAM149A,LETMD1,CNRIP1,CP,CPS1,SH2B1,SNCAIP,CSF2RA,ARHGEF10,OSBPL3,CSNK1G3,PDE4DIP,CST3,SLITRK5,CFAP61,NRSN1,TMEM170A,DNAJC6,HP1BP3,DDX46,DPH1,FAM135B,APH1A,MBNL2,TUBD1,RCAN2,SEZ6,ANKMY1,FCGR1B,SEC24B,FER,FGF11,FGF14,TMEM164,ATP5PD,AGAP3,EFCAB2,APOPT1,ARFGAP2,ZNF605,CELF1,STAU2,AP4B1,DKK3,MEGF10,CHL1,TRAF3IP2,JPH4,ERAP1,KIAA1841,KDM2B,LOXL3,LILRA2,RAPGEF4,GRIA2,DIDO1,HPS5,FRMD5,ARHGAP19,VSIG4,AGBL5,HMX1,ZDHHC15,LRRC75A,LIX1,JAK2,GPR62,KCNJ3,KCNK2,SYTL4,SMAD1,MAP4,MARK1,POC1B,MSR1,MYO9A,FXYD6,NDP,NNAT,CNOT4,DDR2,SNTG1,PCMT1,CDK18,PDGFRA,GNG2,ABCB1,GDAP1L1,FAM218A,A2ML1,RETREG1,GPSM2,JAKMIP1,SCHIP1,NXPH1,LRRN3,GRAMD1C,HYDIN,VPS13C,CNTLN,PTPRE,PEX5,DBX2,ZMAT4,FIGN,RFX5,RGS12,ARHGEF10L,NUDT11,RNASEL,ZFHX4,EXD2,ATP8B4,ABCA11P,RYR3,MAPK12,SH3GL3,FERMT1,CHD9,FBXO11,ST3GAL3,PPP4R3A,RAB3GAP1,SLC11A1,SCMH1,SNRPN,ENKUR,KIF1B,CDK19,NKAIN2,CEP68,STXBP1,AJAP1,FGD4,TMEM150C,ASTN2,C12orf76,DDHD2,FAM208A,FBXW11,TCEA1,CLASP1,SZT2,SYNE1,NAT16,PUM2,HIF3A,LEFTY2,DDHD1,FAM155A,UGT8,SLAIN1,BCL2L13,VLDLR,NDRG4,WNK1,SLC30A4,ZXDA,STOX2,ADAMTS9,SCG2,PCDH15,GAL3ST3,SLC17A7,KCNAB1" MicroRNA hsa-miR-182:PITA hsa-miR-182:PITA_TOP PITA 2.25E-80 1.26E-76 1.06E-79 9.76E-79 155 479 "ADCY2,ADCY6,ADD3,SNX30,GPR158,KLHL13,LRRC7,PDZD4,CDC42BPA,ANK3,ARHGAP5,ARHGDIA,NUMB,ATP1B3,JAZF1,CALM1,ARHGEF2,SEPT7,FOXN3,SOCS6,NMT2,QKI,MAP4K4,CNN3,SLC4A7,BAG4,MYRIP,IGDCC3,CLOCK,PREPL,AATK,TENM4,LRIG1,CSNK1E,ERC2,USP6NL,MYADM,RIMS3,GIT2,ELMO1,RHOBTB1,KIF19,DLG2,DLG3,DSCAM,DYRK1A,YAF2,APH1A,MBNL2,EGR3,EIF5,ELAVL2,RGS17,EPHB1,KCNMB2,SLC43A2,NCALD,EZH1,NRN1,ATP8A1,FOXF2,FOXO3,KHDRBS3,CHL1,AHCYL1,NCKAP1,GK,TOX3,KDM2B,LPAR4,GRM5,BACH2,ZIC5,KTN1,L1CAM,SMAD1,CHIC1,MEF2C,MEIS2,MITF,TAGLN3,PABPC1L2A,NAP1L1,NELL1,NF1,NKX2-2,NPTX1,NRCAM,OCRL,PC,PCDH8,PCMT1,GPR173,GPR85,TMOD2,ANLN,RETREG1,PCDH18,HMGCLL1,LRP12,FAT3,MED1,PKN2,PTCH1,FAM120C,TMEM145,RALGDS,OXR1,RDX,ZMAT4,FIGN,SNX22,FBXW7,SPIN3,MCMBP,ATXN1,PPP1R9A,PPM1E,DOCK10,NTNG1,SHC4,SLC1A2,WDR47,SEPHS1,PALLD,FAM126B,MYT1L,SOX2,ZCCHC24,SOX11,TEX2,ERC1,LRRC4,SYPL1,CAMTA1,CAMSAP2,ADGRL3,FBXW11,SATB2,DOCK9,HEY1,KCTD2,TNS1,VAV2,VLDLR,WIPF1,CA10,CADM2,EVI5,STOX2,WIPF2,FZD3,RTN4,FXR1,ST8SIA2" MicroRNA hsa-miR-518a-5p:PITA hsa-miR-518a-5p:PITA_TOP PITA 2.63E-80 1.48E-76 1.24E-79 1.14E-78 159 506 "ASIC1,KLHL13,PCDH19,SRPX,DPP10,C6orf89,EPB41L5,API5,CDC14B,MIER1,CDK13,STK33,DDX3Y,KSR1,BSN,LDLRAD4,CACNA1E,HAP1,CAMK2A,LGI1,DLGAP2,FOXN3,SYNPR,QKI,AKAP7,SLC4A7,ACBD5,ZNF521,CRMP1,RIMS4,PUM1,SNPH,FRMPD4,LONRF1,DGKB,DNAJC6,ZEB2,FBXL5,SV2A,SRGAP3,MED12,DSCAM,FAM78B,MBNL2,KMT5B,EGR3,PAN3,EPB41L1,ERBB4,NCALD,ACSL4,PTK2B,SCML2,TOMM40L,OLFM1,FGF12,FOXO3,AFF2,NBEA,STAG2,CPLX1,MSTN,GGT7,RND1,TNRC6A,KDM2B,FERMT2,GRM7,CIT,RNF165,SOX21,MIER3,AGFG1,C5orf24,KCNA1,KCND2,KCNK2,KCNK3,KIT,STXBP5,INSYN2,MBNL1,CHIC1,MEF2C,SESN3,MYCN,MYO5A,NEXMIF,NCAM1,NEUROD1,NOVA1,TBC1D25,GPR85,PFKFB4,PIK3C2A,XRN1,PLEC,SMOX,PMP22,POU3F2,PPP2R5E,PTPRD,FAM120C,ARID4A,RDX,ZNF532,ROBO1,FBXW7,KCNIP2,AMER2,SALL1,SEMA6D,ATXN1,ITSN1,FAM102A,CHD9,FNDC3A,EPN2,WDR47,SLC6A1,SLC8A1,CPEB4,RCOR3,IGSF9B,PALLD,SOX2,SOX5,ZCCHC24,SOX11,CDK19,NPAS3,RAP1GAP2,SRPK2,LRRC4,SYT11,PRRC2C,PLCB1,ATP11A,TACC1,ANKRD12,FBXW11,TBX15,SIN3B,SATB2,TCF12,SYNE1,CRTC1,ZFPM2,TNS1,RBFOX2,PCDH20,ZIC1,ADAMTS9,SNX27,KCNAB1,TMEM163,RGS7BP,PIANP,SENP7" MicroRNA hsa-miR-527:PITA hsa-miR-527:PITA_TOP PITA 2.63E-80 1.48E-76 1.24E-79 1.14E-78 159 506 "ASIC1,KLHL13,PCDH19,SRPX,DPP10,C6orf89,EPB41L5,API5,CDC14B,MIER1,CDK13,STK33,DDX3Y,KSR1,BSN,LDLRAD4,CACNA1E,HAP1,CAMK2A,LGI1,DLGAP2,FOXN3,SYNPR,QKI,AKAP7,SLC4A7,ACBD5,ZNF521,CRMP1,RIMS4,PUM1,SNPH,FRMPD4,LONRF1,DGKB,DNAJC6,ZEB2,FBXL5,SV2A,SRGAP3,MED12,DSCAM,FAM78B,MBNL2,KMT5B,EGR3,PAN3,EPB41L1,ERBB4,NCALD,ACSL4,PTK2B,SCML2,TOMM40L,OLFM1,FGF12,FOXO3,AFF2,NBEA,STAG2,CPLX1,MSTN,GGT7,RND1,TNRC6A,KDM2B,FERMT2,GRM7,CIT,RNF165,SOX21,MIER3,AGFG1,C5orf24,KCNA1,KCND2,KCNK2,KCNK3,KIT,STXBP5,INSYN2,MBNL1,CHIC1,MEF2C,SESN3,MYCN,MYO5A,NEXMIF,NCAM1,NEUROD1,NOVA1,TBC1D25,GPR85,PFKFB4,PIK3C2A,XRN1,PLEC,SMOX,PMP22,POU3F2,PPP2R5E,PTPRD,FAM120C,ARID4A,RDX,ZNF532,ROBO1,FBXW7,KCNIP2,AMER2,SALL1,SEMA6D,ATXN1,ITSN1,FAM102A,CHD9,FNDC3A,EPN2,WDR47,SLC6A1,SLC8A1,CPEB4,RCOR3,IGSF9B,PALLD,SOX2,SOX5,ZCCHC24,SOX11,CDK19,NPAS3,RAP1GAP2,SRPK2,LRRC4,SYT11,PRRC2C,PLCB1,ATP11A,TACC1,ANKRD12,FBXW11,TBX15,SIN3B,SATB2,TCF12,SYNE1,CRTC1,ZFPM2,TNS1,RBFOX2,PCDH20,ZIC1,ADAMTS9,SNX27,KCNAB1,TMEM163,RGS7BP,PIANP,SENP7" MicroRNA hsa-miR-509-5p:mirSVR_highEffct hsa-miR-509-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.10E-80 1.74E-76 1.46E-79 1.34E-78 218 956 "RALGAPA1,ACLY,CSMD2,BRAP,OSBPL1A,TAOK1,ADGRF5,AMPD2,MAP4K3,ALS2,VAT1L,CDC14B,ASGR1,NUMB,B3GALT2,DPY19L3,ADGRB3,ARHGEF7,THSD7A,CAMK2D,CAST,RUNX1T1,ZNF501,KRIT1,METTL6,INA,CD38,LRBA,ARHGEF2,LRRFIP1,LGI1,NPIPA1,SRSF11,PPT2,TMEM155,CNTN1,AKAP6,COL4A5,ZNF521,ENTPD4,TRIM69,FEZ2,OSBPL3,SIPA1L1,PHACTR3,CTNND1,KCTD8,DDX46,SACS,G3BP2,WDR20,CHRDL1,HS3ST4,USP3,DPYSL2,GOLT1B,EDIL3,EDN3,YAF2,EGR3,KCTD3,VPS13B,COQ7,RABEPK,ABCA8,CORO2B,TOMM40L,MED12L,GTF2IRD2,OLFM1,SPSB4,BAIAP2,TMEM164,PRKAG2,FHL1,SYNCRIP,RGPD5,JKAMP,NBEA,ZCCHC17,TMEM107,SMC2,FYB1,GALC,IP6K3,ERAP1,NEU3,TUBGCP4,MSTN,ARFIP1,SESN1,GHR,TOX3,TNRC6A,MSL3,ZNF638,WDFY3-AS2,ADGRA3,GPM6B,TDRKH,FUT10,GRIA2,GRM1,CLASRP,IL1RAPL1,UBE2QL1,ZHX1,NXPH2,LINC01102,HSP90AA1,IL6ST,ZNF678,KCND2,SYTL4,HECTD2,MBNL1,MDM4,MEIS1,MN1,ERICH3,MTTP,NAP1L1,NF1,NRCAM,NRDC,NRGN,SETD4,OGG1,PCDH8,PDGFRA,ENPP2,GPR85,CCSER2,RETREG1,MAPKAP1,RC3H2,EPB41L4B,LRRN3,KANSL1,RELN,BCAS3,CYBC1,SPDL1,TMEM260,ZSCAN32,PTPRB,PTPRD,PTPRE,PTPRZ1,NKAIN1,RADX,MORC4,GTDC1,FIGN,ZFHX4,CCDC82,CARF,RPL15,UEVLD,CNTNAP3,RYR3,NCBP3,SCN2A,SCN7A,ASIC4,PEAR1,CASC3,SCAF8,KIF21A,ITSN1,SH3GL2,FBXO11,FNDC3A,NLGN1,SLC15A2,ATF7IP,TET1,RCOR3,USP33,FNBP1,KDM3A,CLUAP1,KDM4C,ZNF423,TAB2,CLASP2,CLSTN2,SSPO,NECAB1,SYN2,SLC37A2,FBXW11,EHBP1,ZEB1,TRIM2,RPGRIP1L,PCDHB7,ITGB3BP,TGFBR3,AKTIP,TLL2,BHLHB9,ERCC6L2,ANO5,TMEFF2,MEAF6,VLDLR,RICTOR,SF1,ZNF24,FMN2,POLR3H,UPF3A,MFF,STOX2,SNX27,MPPE1,UBE3B" MicroRNA hsa-miR-659:mirSVR_highEffct hsa-miR-659:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.21E-80 1.80E-76 1.51E-79 1.39E-78 227 1033 "KCNH8,KLHL32,SLITRK1,PWWP2A,RNF150,CC2D2A,HFM1,SMIM17,ALCAM,ABCD2,UNC79,ANK3,NCOA1,ATP2B1,ZNF583,B3GALT2,DOCK11,TTLL9,RGS9,BID,DST,SYNJ2,SCAPER,KALRN,SPAG9,MAP7,CD86,CBFA2T2,SEPT7,CDC42,CDH8,LGI1,TIGD7,CHM,ZBED5,RAB33A,CNN3,IQCK,CABP1,AKAP5,SLC4A7,SLC35F1,FAM171B,ENTPD4,NCOR2,FEZ2,ARHGEF10,SLITRK5,CTNND1,ECE2,HDAC9,DCAF8,DNAJC6,JAKMIP2,MAGI2,RABGAP1L,FAM107B,DMTF1,ABI1,DTNA,DNM1L,FCF1,SEMA3D,FRY,TUBD1,EPHA5,ANKRD13B,NCALD,SPEG,TLR7,SIRPB1,F5,CLVS1,SCML2,CEP78,FCGR3A,GORAB,SLC9B2,FGF12,FGF14,NELFCD,NBEA,POMT1,ZBED3,ATP2C1,STAU2,GAD1,BRPF3,FAM120B,ARPP21,DISC1,KIAA1841,PPARGC1A,LYVE1,GK,TNRC6A,PCDH11X,GNAS,FUT10,GRIA4,FAM19A2,LINC01551,VSIG4,NEGR1,CELF5,SMAP1,TUBB2B,JAK2,KCNMA1,KCNN3,KHK,LAMP2,NAT8L,MAP4,SYT9,IL17D,KCTD6,MOBP,BLOC1S2,THYN1,DDX25,MYO6,NAP1L1,SLCO1C1,NOVA1,GPR88,OPHN1,GPR137C,CNTN3,PCSK1,BEST3,PIK3C2A,SNX10,MTRF1L,PRIMPOL,SPATA6,MINDY2,PPP3CB,PRKACB,PRKCB,MAPK9,PRPH,RELN,SNRK,MDGA2,UHRF1BP1,MTMR10,SPDL1,TMEM260,PTX3,ZSCAN2,TUG1,PPP2R3C,ACSS3,REV3L,ZFHX4,ROBO1,NEK11,RPL15,UEVLD,RTKN,CCDC112,TMEM156,SEMA6D,LRFN5,SCN2A,FNIP1,TNFRSF19,SH3GL3,NLGN1,PPP4R3A,FAM214B,SCMH1,BTBD7,SLN,ZNF667,TTC17,IFT122,LIMCH1,TMCC1,UNC80,TRERF1,ZC3H13,KIF1B,CDK19,SPART,NFASC,SRPK2,CEP68,GANAB,NSFL1C,SYP,SYPL1,C12orf76,DNMBP,FAM208A,ADGRL3,IQCE,TCF7L2,TCF12,WDR7,DOCK9,CYB561A3,ACTR6,TPM3,RGMB,PRMT8,BCL2L13,CLDND1,RICTOR,SLC13A3,ZIC2,KCNT2,POLR3H,SLC30A4,RNF103,HPS4,MDH1B,NAV3,PDSS2,GOPC,PAK5,SMIM8,PHTF2,FRMD6,DPF3,SLC4A10" MicroRNA hsa-miR-29a:PITA hsa-miR-29a:PITA_TOP PITA 3.74E-80 2.10E-76 1.75E-79 1.61E-78 170 583 "ASIC1,XKR4,SLITRK1,OSBPL6,PITPNM2,ANK3,GPAM,USP37,SHROOM2,TMEFF1,ZBTB10,ATP2B1,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,FMNL3,CDC42,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,SLC4A7,CPS1,CREB5,CRMP1,NCOR2,OSBPL3,ARHGEF4,CTNND1,NRSN1,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DLG2,FAM57B,ABI1,DRP2,ARRDC4,FEM1B,SH3GLB1,EFNB3,KMT5B,PLEKHA1,ELN,ANKRD13B,MED12L,MEX3B,FOXO3,PSD2,AFF2,ZCCHC17,STAG2,GAB1,SESN1,PCDH17,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,C5orf24,ZIC5,TUBB2B,KCNMA1,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NAP1L3,NFIA,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,PRKAB2,WBP1L,SIDT1,SNRK,EML5,PEX5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,BSDC1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,KCNIP2,ATXN1,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,SCN3B,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,CAMSAP2,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,ZFP91,RBFOX2,TPM1,ZNF346,FNDC5,TUBB2A,AMOT,UBTF,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-29b:PITA hsa-miR-29b:PITA_TOP PITA 3.74E-80 2.10E-76 1.75E-79 1.61E-78 170 583 "ASIC1,XKR4,SLITRK1,OSBPL6,PITPNM2,ANK3,GPAM,USP37,SHROOM2,TMEFF1,ZBTB10,ATP2B1,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,FMNL3,CDC42,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,SLC4A7,CPS1,CREB5,CRMP1,NCOR2,OSBPL3,ARHGEF4,CTNND1,NRSN1,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DLG2,FAM57B,ABI1,DRP2,ARRDC4,FEM1B,SH3GLB1,EFNB3,KMT5B,PLEKHA1,ELN,ANKRD13B,MED12L,MEX3B,FOXO3,PSD2,AFF2,ZCCHC17,STAG2,GAB1,SESN1,PCDH17,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,C5orf24,ZIC5,TUBB2B,KCNMA1,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NAP1L3,NFIA,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,PRKAB2,WBP1L,SIDT1,SNRK,EML5,PEX5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,BSDC1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,KCNIP2,ATXN1,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,SCN3B,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,CAMSAP2,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,ZFP91,RBFOX2,TPM1,ZNF346,FNDC5,TUBB2A,AMOT,UBTF,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-29c:PITA hsa-miR-29c:PITA_TOP PITA 3.74E-80 2.10E-76 1.75E-79 1.61E-78 170 583 "ASIC1,XKR4,SLITRK1,OSBPL6,PITPNM2,ANK3,GPAM,USP37,SHROOM2,TMEFF1,ZBTB10,ATP2B1,N4BP2L1,BCL7A,WASF1,LDLRAD4,CACNA1A,CAMK2G,FMNL3,CDC42,DLGAP2,SRSF11,FOXN3,QKI,MAP4K4,CNR1,PCYT1B,COL4A5,AKAP5,SLC4A7,CPS1,CREB5,CRMP1,NCOR2,OSBPL3,ARHGEF4,CTNND1,NRSN1,USP6NL,FAM131B,HDAC4,KIF26A,DBT,ELMSAN1,DDX46,DLG2,FAM57B,ABI1,DRP2,ARRDC4,FEM1B,SH3GLB1,EFNB3,KMT5B,PLEKHA1,ELN,ANKRD13B,MED12L,MEX3B,FOXO3,PSD2,AFF2,ZCCHC17,STAG2,GAB1,SESN1,PCDH17,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,RNF165,ADAMTS6,ZHX1,BACH2,MIER3,HMGCR,HNF4G,NEGR1,IGF1,C5orf24,ZIC5,TUBB2B,KCNMA1,TTYH2,MAT2A,MEST,SCAMP5,MYCN,NEXMIF,NAP1L3,NFIA,NFIX,PALM,ENPP2,GNG2,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,PRKAB2,WBP1L,SIDT1,SNRK,EML5,PEX5,NKAIN1,TMEM255A,RAP1GDS1,OXR1,BSDC1,REV3L,FIGN,NUDT11,LGI2,SETD5,ROBO1,KIRREL1,SNX22,FBXW7,KCNIP2,ATXN1,SMPD3,TRA2B,SGK1,PPM1E,CPEB3,NAPB,TET1,FAM126B,MYO16,SCN3B,HECW1,PEG10,SPTAN1,ERBIN,ELOVL4,CEP68,STX1A,PRRC2C,ADAMTS17,SYN2,CAMTA1,CAMSAP2,TCF4,HIF3A,DICER1,AP4E1,ENHO,TIAM1,ZFP91,RBFOX2,TPM1,ZNF346,FNDC5,TUBB2A,AMOT,UBTF,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,ADAMTS10" MicroRNA hsa-miR-369-3p:TargetScan hsa-miR-369-3p TargetScan 3.83E-80 2.15E-76 1.80E-79 1.65E-78 152 461 "ABAT,ABR,ACLY,CSMD2,ADCY5,GRAMD1B,ESYT2,AP2A1,PCDH19,ARHGAP20,PCDH10,FAM135A,LRCH2,APBB2,GAS7,APP,ARHGAP5,PDE8B,DST,LDLRAD4,CDH2,DCLK1,NOG,NUMBL,CFL2,CNOT8,DNAJB5,QKI,HECTD1,NIPBL,NRG2,HAPLN1,ABCG1,PHACTR3,PLXNA4,KIAA0087,GIT2,PITPNC1,DNAJC6,MFAP3L,KLHL3,RABGAP1L,FAM107B,DLG3,DMD,RCAN1,DYRK1A,EBF1,SEMA3D,MBNL2,PLXNC1,EPB41,DENND4A,CEP85L,EYA1,MED12L,FOXG1,FLT1,APOPT1,FYN,CHL1,GABRB3,NCKAP1,GBX2,GFRA2,FREM1,GRIA1,FAM19A2,IL1RAPL1,RASSF8,HLF,NKD1,RBPJ,PLD5,CDH20,KCNJ3,KCNN3,KTN1,LSAMP,MAP2,MBNL1,LRP1B,MEIS1,MGAT3,AFF1,MMP16,MYO9A,NF1,NFIA,NFIX,NPTX1,NPTX2,HCN1,OCRL,OPA1,P2RY1,PAX6,PDE3A,PDE3B,PDE4A,PDE4D,PDPK1,CDK14,FAM216A,PURG,PPP2R2C,PRKAB2,CEP41,PKIA,OCIAD1,PTPRG,RAB5B,OXR1,ARID4A,BSDC1,RFX4,PRIMA1,RORB,HUNK,AMER2,SATB1,CSRNP3,SCN2B,FNIP1,PPP1R9A,ARHGEF40,MBD5,SCN3B,IQSEC2,CDK19,NKAIN2,GSE1,PRRC2C,ATMIN,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HEY2,RBFOX2,DOK6,RBFOX3,KCNK12,PPP1R3F,RGS7BP,GOPC,JMJD1C,PIANP" MicroRNA hsa-miR-193a-5p:mirSVR_lowEffct hsa-miR-193a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.95E-80 2.22E-76 1.85E-79 1.70E-78 250 1239 "ACADM,ASIC2,ABHD6,GALNT13,PWWP2A,BEND6,OLMALINC,NLGN4X,AP2A2,PCDH19,ZNF578,TAOK1,PHF12,CDC14B,MARCH3,MARK4,DACT3,SLC2A11,RNF182,SNAI3-AS1,RGS9,BCL7A,CFLAR,LDHD,CACNB4,CAMK2G,CAST,KRIT1,USP6,CDK11B,LRRFIP1,CNOT8,NRXN3,NRXN1,FAM189A2,SULT4A1,CNTFR,COL11A2,SLC4A7,COX4I1,SMARCAL1,CHD1L,FAM171B,GDA,FEZ1,VAC14-AS1,PDE4DIP,SLITRK5,UBXN2A,FAM131B,GPRASP1,DAPK1,CHRDL1,NYAP1,DPH1,TOM1,ABCC9,GOLT1B,CELSR3,EBI3,EMX2,RASGRP2,SRRM1,TMEM74,ETV1,F3,PTK2B,TAOK3,FDFT1,TESK2,GTF2IRD2,POLR1B,FGF13,FGF14,IP6K2,AGAP3,SPECC1,FAM49B,NSG1,GABRA2,AHCYL1,ARPP21,NCKAP1,DNER,ALDH1L1,CYP46A1,DBF4,GLI2,MSL3,GPR17,STON1,GRIA2,ADAMTS13,GRM2,GRM7,ZBTB49,LINC01551,HPS5,PADI2,KLF12,VSIG4,SYNPO,HMGCL,NEGR1,TCEAL6,ATCAY,ZIC5,KNDC1,DISP2,LIX1,IL11RA,JAK1,SLC35G1,KCNH1,KCNJ10,GATD1,STXBP5,ASPRV1,MAP2,MARK3,MEIS1,SRSF12,MMP16,JAKMIP3,MSR1,MYO5A,NELL2,NOS1,NUMA1,OXTR,ZDHHC22,DPY19L2P2,CDK18,GNG2,PFKFB2,CDK14,NLGN3,A2ML1,ST8SIA5,SDK2,SPATA6,PPARA,CRLS1,PPP5C,RASGEF1B,PRKACB,EPDR1,GRAMD1C,HYDIN,GDPD1,SYTL2,TMEM260,RAB3IL1,SUSD4,NWD1,RAP1GDS1,MSANTD2,ZDHHC4,RGS4,TTLL7,MRPS18A,SLC25A36,RIC8B,ZFHX4,ARMC5,CCDC102B,SNX22,NEK11,FOXRED2,TNFRSF19,SLC30A10,SFPQ,DOCK10,MAGI3,CTXN2,SLC1A3,PPP4R3A,DHX30,ZNF430,SLC14A1,SLIT1,RCOR3,SNRPN,KDM4B,SCN3B,SON,PDZD2,SOX1,TNIK,NMNAT2,GLT8D1,LHFPL4,BEX1,TAB2,ZSCAN29,PHLDB1,SEPT3,NSFL1C,KLHL7,SYT11,FGD4,ANKRD12,TAL1,TBCEL,ATMIN,TPCN2,TRIM2,TCF12,CLASP1,SYNE1,SLC19A3,OBSL1,NSD1,VWCE,DICER1,CRB1,GPR161,TIAM1,MTMR14,TJP1,ERCC6L2,KCTD2,TRIO,TRO,PPIL6,LRTM2,TUB,RPRM,EIF4ENIF1,BCL2L13,PLPPR2,NSD2,PORCN,XRCC4,ZIC2,ZNF74,DPYSL5,LAMP5,PRDM2,SLC38A1,LMAN2L,RNF103,TUBA1A,TMEM178A,HPS4,SLC17A7,LINC00632,FAM47E,SLC17A6,JMJD1C" MicroRNA hsa-miR-1270:mirSVR_highEffct hsa-miR-1270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.94E-80 3.90E-76 3.25E-79 2.99E-78 230 1063 "KCNH8,ACTN2,CSMD3,ADCY2,HECW2,CC2D2A,TAOK1,ARHGAP20,BBOX1,FAM135A,OGT,APAF1,GPAM,MIER1,ARNTL,STK33,CCDC74A,ATP1B3,B3GALT2,N4BP2L1,ATP6V1G2,TTLL9,ADGRB3,IL33,MMD2,CACNA1B,THSD7A,KALRN,PTBP2,CCNH,LRBA,ARHGEF2,LGI1,MAGI1,TIGD7,RCBTB2,CASC2,LHX2,FAM19A5,PCYT1B,COL4A5,SUMF2,CHD1L,SLC35F1,VCAN,NRSN1,HDAC9,EARS2,IST1,PITPNC1,YTHDC1,MFAP3L,ALKBH8,RHOBTB1,ZNF582-AS1,DMD,HS3ST4,NR1D2,CPEB2,DTNA,AASDH,EDIL3,CNNM1,YAF2,PHF20L1,APH1A,MBNL2,COPS4,RGS17,TMEM35A,C8orf37,EPHB1,PIPOX,F8,CLVS1,FAM198B,TMEM132C,FCGR1A,CEP78,ZNF589,SLC9B2,MED12L,FGF13,FGFR1,PRKAG2,FOXM1,SPECC1,APOPT1,KHDRBS3,KBTBD12,FYB1,ZMAT1,GABBR1,GABRA2,ZMYND11,DNER,GGT5,PPARGC1A,GLI2,GLYR1,PCDH11X,ZNF638,DCLK2,CNDP1,GPR12,MCHR1,GRIA4,NR3C1,GRM7,ZNF496,RASSF8,ACOT7,HMGCL,SHISA6,IRF8,IGFBP1,ZIC5,LRRCC1,DIPK1A,NME9,JAK2,KCNA4,KCNJ5,KIF5A,HECTD2,MAOB,AFDN,ERICH3,MSR1,MYO7A,MYT1,NEK1,NFE2L2,NODAL,NRCAM,NTRK2,P2RY1,GLIPR1L2,SNTG1,CNTN3,PRTG,OLA1,PCDH18,HMGCLL1,NECAB2,MAGEL2,EPB41L4B,NXPH1,HYDIN,RELN,VPS13C,WDR25,BDNF-AS,TMEM260,CASTOR1,USP47,DBX2,RADX,HKR1,SLC6A15,ZYG11B,GTDC1,RFX4,RGS7,SLC25A36,TMLHE,MEG3,CSRNP3,SCN3A,LRRTM4,SCP2,COPZ1,NLGN4Y,ZFP30,NTNG1,SHC4,NUBPL,DHX30,SLC12A4,BTBD7,SPHKAP,SLC22A4,LIMCH1,SNRPN,MYO16,UNC80,SON,PDZD2,FNBP1,HECW1,KDM4C,RBM26,LMO3,CLASP2,CLSTN2,SST,NXT2,STAU1,ELOVL4,ZC3H4,PLCB1,MTCL1,FAM208A,UNC5D,TMEM136,TBX15,TRIM2,SYNE1,FAM189A1,SIK3,DICER1,C18orf54,AP4E1,TJP1,BEX4,TPM1,ANO5,UGT8,OSBP2,USP1,LYPD6,DHX33,CA10,EMSY,PRDM2,NAV3,EPM2A,GOPC,ST7,RNF170" MicroRNA hsa-miR-18a:mirSVR_highEffct hsa-miR-18a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.00E-80 5.06E-76 4.21E-79 3.87E-78 188 719 "KCNH8,AS3MT,XKR4,SLC25A25,TMCC3,ADD3,PLEKHH1,PWWP2A,BEND6,GPR158,ALCAM,BCAR3,BBOX1,OGT,ANK3,MAP4K3,ANXA7,CNTNAP1,VAT1L,NCOA1,ATM,ATP1B3,NOL4,NAE1,CA8,CA12,ZNF501,USP6,SYNGR3,LRBA,CDC42,LRRFIP1,CASC2,CLCN4,NRXN1,COG1,QKI,AKAP7,SLC25A27,COL9A2,TBPL1,AHCTF1,SLC35F1,CPS1,RNF14,CLIP3,RGS6,ATRNL1,SIPA1L1,SOCS5,DZIP3,GREB1,NRSN1,RIMS2,DCAF4,DOCK4,HDAC9,PHF19,LIN54,MATR3,TOMM20,DBI,PITPNC1,HP1BP3,TMCC2,SEC16A,DTNB,SYT15,PHF20L1,SORBS3,VPS13B,EPB41L1,EPHA5,EFS,TLR7,DLC1,CEP78,MED12L,FGF1,FGF12,SUCO,KHDRBS3,STAU2,OGA,CAB39,WASF3,SULT1C4,PPARGC1A,GLRB,STARD3,GNAS,NR3C1,HLF,HNMT,ZNF491,ZDHHC15,TCEAL6,HSF2,SOWAHA,INSYN2,MBNL1,OCRL,GPR88,PCSK1,PDE1A,PDE4D,PDE1B,PDGFRA,GPR173,CDK14,PIK3C2A,ZNF655,EXOSC10,PRRX1,SH3KBP1,PPP3CB,PRKACB,MAPK4,HYDIN,DIRAS2,MASP1,VPS13C,SIDT1,SNRK,IQSEC3,NWD1,RBBP6,RBBP8,FIGN,ARHGEF10L,RNASEL,TRAPPC13,AMER2,SATB1,CSRNP3,LINC00461,COPZ1,ZFP30,ITSN1,MAGI3,ZNF365,BTBD3,SLC6A11,RAB3GAP1,SMARCC2,DOP1A,SON,PDZD2,KDM3A,KDM4C,TEX2,IDI2-AS1,BEX1,CDK19,TSPYL2,SPART,C11orf87,NKAIN2,NXT2,CEP68,FGD4,VPS13A,TMEM150C,ANKRD28,C12orf76,ANO4,ZFP90,FRYL,SIK3,TEK,TLL2,DAAM2,R3HDM1,NPL,TRPC3,PLEKHH2,WIPF1,ZBTB14,TRIM9,CELF4,SYNC,EMSY,CADM2,STOX2,ADAMTS9,ITM2C,EPM2A,CBLN2" MicroRNA hsa-miR-138:mirSVR_highEffct hsa-miR-138:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.03E-79 5.78E-76 4.80E-79 4.42E-78 206 862 "ACADM,ABHD6,SYS1,UNC5A,PWWP2A,GPR158,BCAR3,ZFAT,SUGT1P4-STRA6LP-CCDC180,PKP4,GPAM,VAT1L,TNRC6C,CDK10,STK33,ZSCAN18,ATM,STX16,ATP2B2,DPY19L3,ADAM23,BACH1,SEC11C,JAZF1,CACNB2,CAST,LRRFIP1,NRXN3,AKAP7,IQCK,LETMD1,ZNF521,MFSD4A,CHD1L,ZNF385A,SLC35F1,FAM171B,HINFP,ANKRD44,MROH8,SNCAIP,SEC24C,CSF3R,SUSD5,SOCS5,FAM169A,RIMS2,DCAF4,ARHGAP32,KIF26A,DGKG,IP6K1,GIT2,ARMCX2,ZEB2,MYEF2,ELMO1,TMCC2,CCDC3,CHRDL1,USP3,DTNA,DNAJB6,SNX29,EFNB3,PHF20L1,APH1A,KMT5B,RCAN2,GPHN,SRRM1,RASL12,CLVS1,ST3GAL6,BAIAP2,POLK,MEX3B,RGPD5,NBEA,PDLIM5,OGA,MEGF10,ZMYND11,KIAA1841,PPARGC1A,CRCP,GLI2,ZNF638,GNAO1,FERMT2,GPD1,LPAR4,PCLO,GRIA4,GRIK3,GRM7,LINC01551,OPALIN,RBPJ,LIX1,KCNJ3,KCNK1,STXBP5,MAP4,MEIS2,MOV10,SCG3,MXI1,NDP,NEUROD1,OGG1,PAK3,PDE3A,GPR85,GNG2,BEST3,CDK14,HERC2P3,ZNF655,FTO,PCDH18,PRIMPOL,SCHIP1,EPB41L4B,NXPH1,FSD1,VSTM2L,PRKCG,RELN,SAMD9,PXK,OCIAD1,NKAIN1,PID1,USP47,RAD51D,RALGDS,MSANTD2,ZYG11B,RFX4,RGS3,ARMC5,YY1AP1,CLIP1,ZNF354C,ZNF568,TNFRSF19,SELL,ITSN1,SH3GL2,FNDC3A,RPH3A,CCDC88A,KBTBD4,MYH15,ANKRD36,LIMCH1,RIMS1,SNCB,SNRPN,USP33,BDP1,ERC1,SPTAN1,NFASC,PBLD,ZC4H2,KANK1,SULF2,NSFL1C,VPS13A,KAZN,WWC1,TPCN2,ARHGAP9,AHCYL2,SIRT1,DICER1-AS1,ZFPM2,CRB1,SLC44A1,ARL10,NPL,TPM4,ELP5,AMACR,TRO,TRPS1,RUSC1,RFTN2,BEST1,CFAP298,PCDH20,ZFP37,ZNF19,PLPP4,PCDH15,SLC17A7,FIP1L1,C12orf4,CASC15,JMJD1C,SSPN,NETO1,SLC4A10,PRRT4" MicroRNA hsa-miR-711:mirSVR_lowEffct hsa-miR-711:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.10E-79 6.16E-76 5.11E-79 4.71E-78 243 1181 "TTYH1,ASPHD1,KDM5D,CSMD2,SLC25A25,FMNL2,ADARB2,GALNT16,ADCY6,ADD2,KIAA1211,FAHD2CP,NLGN4X,LRRC7,PCDH10,ZNF687,AMPD2,DPP10,APBB1,EPB41L5,APOC2,CASK,LINC00173,MARK4,DACT3,ATP6V1G2,ATP6V0A1,ADAM15,RGS11,BID,LDHD,CDK5R1,NIPA1,RAB29,MYRF,BTRC,CACNA1E,TRIM41,RUNX1T1,CBFA2T2,ENTPD6,ZBED1,GPR37L1,CPNE6,CLTA,SLC4A8,TOGARAM2,ZNF385A,C2CD2,RGS6,SEC24C,FEZ1,NCAN,PITPNM3,RUBCN,USP6NL,CX3CR1,ARHGAP32,KATNAL2,CENPL,ACY3,IP6K1,ELMO1,MFAP3L,COPS7A,POM121,RABGAP1L,GRIN3A,OLIG1,RPS6KL1,DYNC1I1,DNM2,SLC25A18,DRP2,DTNA,DNM1L,SNX29,HIPK3,HEYL,SEMA3D,CELSR3,PHF20L1,MRO,GOLGA7,EIF4G1,EIF5,ELN,C3orf18,EIF1,VPS13B,EPHA5,MRPL10,RTN3,DNAJC27,PTK2B,FGF11,SPSB4,WDR83,SPECC1,ARFGAP2,ZNF605,MEGF10,BRPF3,TUBA8,PCDH17,LNX1,CNDP1,PRLHR,GRB10,GRIA1,RFFL,GRIN1,GRM5,CIT,FAM19A2,RNFT2,CELF3,SMAP1,C5orf24,LIX1,C2CD4C,KCNA6,KCNMA1,STXBP5,MAP4,MEIS1,MGAT3,SCAMP5,AFDN,MTR,ZNF862,NELL1,NKX2-2,NPTX2,NRCAM,NTRK3,NUMA1,TBC1D25,OGG1,ZDHHC22,DPY19L2P2,PCSK5,PDYN,GDAP1L1,CAMKV,PLCB2,PLCL1,PLP1,EPB41L4B,POLR2F,VSTM2L,KLK6,WDR25,NCR3LG1,BDNF-AS,PTK2,TTC13,RASGRF1,RET,GTDC1,RGS12,KCTD17,MRPS18A,SLC25A36,RAVER2,SPIN3,KIAA0895L,ABCA11P,KCNIP3,NCBP3,SALL1,ATXN2,ASIC4,CASC3,FAM102A,FERMT1,MYO18A,R3HDM2,ST3GAL3,WDR37,FAM81A,SLC11A1,ATF7IP,ARFGAP1,NAXD,SMARCD3,INTS9,RCOR3,IGSF9B,ANKRD36,WDTC1,KIF21B,ZSWIM8,CLUAP1,ZC3H13,IQSEC2,CDK19,NPAS3,DDN,NFASC,TAB2,ZC4H2,ERBIN,STAU1,ZSCAN29,PHLDB1,KANK1,VAMP1,SYN1,COBL,MTCL1,PJA1,SIN3B,USP22,WDR7,SYNE1,NAT16,PUM2,SIK3,TLL2,TLR4,TMPO,TRIO,SSBP2,VAV1,CLIP2,NSD2,SLC13A3,LGI4,ZNF24,NDRG4,MEIS3,MAP3K12,PRDM2,XKR7,RNF103,PPP1R3F,CAB39L,PCBP4,EPM2A,TIGD6,VANGL2,KLHDC1" MicroRNA hsa-miR-9:PITA hsa-miR-9:PITA_TOP PITA 1.16E-79 6.53E-76 5.42E-79 4.99E-78 171 594 "ASIC1,ARID1A,GALNT16,SLC12A5,ESYT2,PTCHD1,HECW2,ALAD,ALCAM,PITPNM2,PARG,GPAM,SHTN1,SHROOM2,CDC14B,NCOA1,CCAR2,SYNJ1,MTMR2,CACNA1E,CACNB2,CALB2,KALRN,PTBP2,MAP7,LRBA,ARHGEF2,MAGI1,DLGAP2,FAM19A5,QKI,CNTFR,COL9A1,TBPL1,BAG4,CLOCK,CREB5,NCOR2,MICAL2,SOCS5,ARHGAP24,PHF19,DGKB,TOMM20,DCC,ARMCX2,JAKMIP2,RHOBTB1,SACS,SRGAP3,MTX3,FAM107B,CPEB2,ABI1,PDCD6IP,DYRK1A,CNNM1,TMTC1,FRY,EGR3,TENM1,SEZ6,KCNMB2,TESK2,FGF12,FOXG1,FOXO3,GAD1,BRPF3,MTHFD2,SRCAP,PCDH17,C1QL1,LYVE1,GLS,TNRC6A,PCLO,PTPRT,ADAMTS6,HAS2,KLF12,MIER3,ACOT7,AGFG1,C5orf24,ZIC5,IL12A,KCNA1,TTYH2,NCOA7,MBNL1,SYT9,ADAM11,KITLG,MKLN1,MDGA1,NEK1,NPTX1,GPR88,OPCML,GPR137C,CNTN3,PCSK2,PRTG,GPR85,PIK3C2A,CCSER2,XRN1,PRRX1,PACSIN1,POU3F2,PTPA,CNNM2,SNRK,UHRF1BP1,SLC25A36,PBRM1,RPE65,MCMBP,SGSM1,HUNK,SCN2B,LRRTM4,FNIP1,TRA2B,KIF21A,CPEB3,NTNG1,AMBRA1,ST3GAL3,FAM81A,SLC8A1,CCDC88A,SLC20A2,CPEB4,OGDHL,SMARCE1,TMCC1,WDTC1,SPART,NFASC,ERBIN,ELOVL4,STX1A,VAMP1,ATP11A,ANKRD12,UNC5D,TRIM2,DOCK9,PSD3,FRYL,DICER1,SIRT1,AP4E1,GZF1,DDHD1,NR2E1,RBFOX2,TRIM9,TCEAL7,CELF4,ZBTB38,SLC30A3,ITM2C,WIPF2,GOPC,FAM13C,PHTF2,FRMD6,DPF3" MicroRNA hsa-miR-1911:mirSVR_lowEffct hsa-miR-1911:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.66E-79 9.33E-76 7.73E-79 7.12E-78 194 768 "TTYH1,NBAT1,ACTN1,AXIN2,SLC12A5,PLEKHH1,ADORA3,ESYT2,KIDINS220,BBOX1,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,ALS2,CDK10,IGDCC4,ARHGAP5,EIF4G3,RNF182,DOCK11,TTLL9,DCAF5,DST,PTBP2,VSTM2A,TMEM257,CDH2,CHN2,SYNPR,CNN3,CREM,PDE4DIP,KIAA0040,ST18,DCAF8,MATR3,C8orf34,HP1BP3,CEP170,ALKBH8,G3BP2,CHRDL1,DYNC1I1,DNAJB6,ABCC5,DNM1L,EBF1,HIPK3,TMTC1,YAF2,C8orf37,DCTN4,EIF1,SEZ6,SRRM1,SRARP,F3,FCGR1A,ZSCAN30,ZNF589,FGF13,POLK,SEC23B,FOXO3,SGIP1,ST6GALNAC3,STAU2,DENND2A,MTHFD2,DISC1,ATP8A2,GART,GCNT2,ARFIP1,PPARGC1A,KIRREL3,CRCP,PCDH11X,GNG4,GPR17,GPR34,PLCD4,CIT,BVES,PSIP1,ARHGAP36,ELOVL5,HSF2,FAM95B1,DOCK7,USP54,KIF5C,HECTD2,ARHGAP12,ASPRV1,ZFYVE27,TM6SF1,KCTD6,MID1,ADAM22,ZC3H12B,NDUFA5,NFE2L2,NTRK2,OPA1,PCDH8,PCDH9,BEST3,CYTL1,OLA1,FAM216A,PLCL1,STRN3,ING3,PPM1B,PPP2R2C,PPP2R5C,PPP3CB,VSTM2L,GON4L,CNTLN,UHRF1BP1,MTMR10,PTPRN2,FAM120C,ACSM5,CEP97,USP47,FAM184A,ARID4A,RBBP8,SEC61A2,RNF220,SLC25A36,RIC8B,ZNF532,RORB,ELP2,PCMTD2,MRAP2,ADAL,PTGR2,HSD11B1L,ATXN2,SCN2A,SCP2,SOX6,PPP1R9A,ARX,HKDC1,FBXO11,FAM214B,ARHGEF40,SLC20A2,SMARCA4,SMARCE1,TTC17,ANKRD36,TMCC1,SOX5,SP4,KIF1B,RBM26,NKAIN2,NEK4,SULF2,PJA1,CLASP1,PCDHB3,FAM200B,SIRT1,CRB1,AKTIP,SLC44A1,NR2E1,RGMB,ZNF346,PDSS1,PPIL6,SGK3,SLAIN1,WIPF1,KCNT2,REEP1,ZFAND5,MFF,PRDM2,HPS4,VPS35L,LINC00632,FAM47E,PDSS2,DOCK8,ADAMTSL3" MicroRNA hsa-miR-101:PITA hsa-miR-101:PITA_TOP PITA 2.09E-79 1.18E-75 9.74E-79 8.97E-78 154 479 "ASIC1,ACLY,ARID1A,FMNL2,ADCY6,SPOP,UNC79,AMPH,OGT,LRCH2,PPFIA4,APP,TMEFF1,DDX3Y,ATP2B2,KIF1A,CDK5R1,MTMR2,JAZF1,CACNB2,MTMR7,CBFA2T2,TMEM257,C1orf52,LONRF2,MAGI1,CLCN3,SULT4A1,MYRIP,CSNK1G3,SOCS5,APPL1,CTNND2,KIAA0408,LONRF1,SPATA2,TIAM2,MAGI2,G3BP2,RABGAP1L,RAB39B,CPEB2,DYRK1A,ABCC5,YAF2,KMT5B,EGR3,ELN,TMEM35A,EPB41L1,EYA1,ATP8A1,FGFR3,MEX3B,DOT1L,STAG2,KAT7,FAM222A,HAS2,NEGR1,AGFG1,SMAP1,SOWAHA,JAK2,KCNA1,KCNA6,IPO5,STMN1,PACRG,MARK1,MBNL1,MEST,MITF,XRRA1,MYCN,NEXMIF,NACA,NAP1L1,NEUROD1,NOVA1,NRCAM,CLDN11,PCDH8,CDK18,PDE4D,ENPP2,GPR85,PURG,FA2H,FAT3,POU3F2,LRRN3,PTCH1,USP47,KHDRBS2,REV3L,NUDT11,ZFHX4,ZNF532,SETD5,ROBO2,RORB,FBXW7,RYR3,ATXN1,SCN2A,SGK1,CPEB3,ABLIM3,BTBD3,CCDC88A,SLC12A2,TMEM132D,SMARCA4,SOX11,SP2,TEX2,SRPK2,POGZ,LRRC4,ERBIN,GSE1,PRRC2C,ADAMTS17,PLCB1,SYT4,CAMTA1,TAL1,PDLIM2,FBXW11,TCF4,DMXL2,PUM2,FRYL,HHIP,HEY1,RIMBP2,KAT6B,TRPS1,SSBP2,CADM1,PITPNB,FLRT2,PCDH20,ZIC1,TRIM9,EMSY,MPPE1,SLC17A6,HNRNPA3,CERS6,ADAMTSL3,ADAMTS10,KLHDC1" MicroRNA hsa-miR-6835-3p:TargetScan hsa-miR-6835-3p TargetScan 2.23E-79 1.25E-75 1.04E-78 9.55E-78 182 677 "CSMD3,ELFN2,ADCYAP1R1,GRAMD1B,PWWP2A,PTCHD1,HECW2,ARHGAP20,GPRASP2,OGT,CDC42BPA,C6orf89,APC,GPAM,APP,PDXK,CDK13,MARCH3,BRINP2,ATP2B1,N4BP2L1,NRP2,FUBP1,MTMR3,JAZF1,LDLRAD4,FOXK1,CAMK2A,RUNX1T1,CBFA2T2,CD38,C1orf52,L3MBTL4,CFL2,RAB3C,NRXN1,CLTC,QKI,IGLON5,ARHGEF6,CNTN1,ARMC8,ACBD5,CREB5,CTNND2,CCDC144A,DOCK4,DCAF8,MATR3,ELMSAN1,JAKMIP2,MFAP3L,MTX3,FAM107B,EXOG,RAB39B,DMD,CDON,CPEB2,FAM57B,DRP2,RCAN1,DYRK1A,EDNRB,PHC2,EFNA3,ABI2,PLXNC1,EPB41L1,RCAN2,RAB9B,RTN3,DLC1,PPP1R1B,MED12L,FHL1,FOXO3,FLT1,PDLIM5,CELF1,FYN,GAB1,GABRB3,GATM,PCDH17,PPARGC1A,CBX1,MAP7D2,GNAO1,GPM6B,GPR37,RFFL,GRM5,HAS2,HTR2A,IL6ST,BRINP3,KCNA4,KCNC2,KLHL23,KCNN3,LAMP2,LIFR,LIMS1,SAMD5,NFIA,HCN1,OPCML,GPR137C,KCNK10,PAK3,CNTN3,PDE1C,PDE3A,PDE1B,PDPK1,GNG2,ANLN,PIK3R1,CDIP1,PRRX1,FAT3,POLG,MED1,PPP2R5C,PRKAB2,CEP41,CNNM2,ANKHD1,PTPRD,NKAIN1,CEP97,RDX,REV3L,GTDC1,FIGN,KLHL11,NUDT11,LGI2,RIMKLA,AP1AR,SATB1,ATXN7,SCN4B,SCN7A,PPM1E,CPEB3,NTNG1,FNDC3A,RIMS1,HECW1,ERC1,NPAS3,NKAIN2,KLHL7,PRRC2C,PLCB1,ANKRD28,PSD3,NSD1,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,HHIP,ASXL3,DDHD1,C5orf64,RBFOX2,AMOT,OSBP2,BCL2L13,DPYSL5,FZD3,NETO1,CBLN2,GAN" MicroRNA hsa-miR-205:mirSVR_highEffct hsa-miR-205:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.74E-79 1.54E-75 1.27E-78 1.17E-77 217 958 "RNF150,PTCHD1,AP2A2,INTS2,MTUS1,HACE1,AK2,ALCAM,CEP126,ABCD2,UPRT,ALS2,PPP4R4,TMEM263,ASPH,ATP2A2,ATP2B1,CFLAR,CALB2,KALRN,AP4M1,CDC27,CDH18,MAGI1,CFL2,CHN1,MS4A7,RAB3C,B4GALT6,CLTA,CLTC,NGEF,QKI,NCOR1,GDA,RGS6,CSF2RA,MICAL2,ATRNL1,NCAN,PDE4DIP,ERC2,PHF14,PNPLA8,CYBB,HDAC9,FGFR1OP2,ZFYVE16,TMEM170A,HP1BP3,GUCD1,SV2B,ZNF582-AS1,CDON,CPEB2,GNE,DNM1L,EDN3,PHC2,ANKRD46,CNNM1,RASGRP1,RBM12,ABI2,CALCRL,EPB41,RCAN2,EPHB1,CEP85L,RTN3,CLVS1,ACSL4,ST3GAL6,ZSCAN30,TESK2,SEC24B,FGF12,CAP2,RGPD5,NOP56,COQ5,EFCAB2,SORBS1,SMC2,ST6GALNAC3,SARAF,PHYHIPL,TRAF3IP2,JPH4,ARPP21,DISC1,LRRC37A6P,IGSF5,SULT1C4,GGT7,GLRB,ZNF638,CBX1,KDM2B,GOLGB1,GPM6A,LILRA1,EML4,STMN2,GRIA2,GRIA4,FAM19A2,HNRNPK,SHISA6,ZNF678,KCNJ16,KCNMA1,IPO5,NCOA7,MARK1,MBNL1,MDM4,CCDC80,NCAM2,NEK1,SMIM11A,HCN1,TBC1D25,CLDN11,PCSK5,PDE1C,PDE3B,OLA1,CDK14,ZNF655,FAM218A,PURG,C11orf49,SEPT4,EPB41L4B,DRAM2,PPP2R5E,PPP3CB,PRKACB,GRAMD1C,PROX1,PSMD13,TMEM260,ZIK1,OCIAD1,C1orf109,ZNF615,ZNF844,SLC25A48,RBBP8,SLC6A15,ZMAT4,RGS12,RIC8B,ZFHX4,RAVER2,MCMBP,LRRK2,ABCA11P,CLIP1,SCN3A,SCN8A,SEC14L1,SH3GL3,CTXN2,SLC2A5,BTBD3,SMTN,SEPHS1,NAPB,TET1,CXXC4,PALLD,SP4,UHRF1BP1L,KDM4C,CDK19,RBM26,SRPK2,ZNF302,SS18,FGD4,PLCB1,COBL,TAF9,CAMSAP2,WWC1,DMXL2,SATB2,CUX2,ZEB1,TNS2,AP4E1,NACC2,ERCC6L2,C5orf64,TP53BP2,TPM4,ZNF384,TTC3,CADM1,FAM155A,AMOT,PCDH20,MICU3,KCNT2,TRIM9,ZBTB16,FSTL5,ZNF184,PCBP1-AS1,ZFAND5,ADAMTS9,CAB39L,PDSS2,HRASLS,SPATA13" MicroRNA hsa-miR-520g:PITA hsa-miR-520g:PITA_TOP PITA 3.24E-79 1.82E-75 1.50E-78 1.39E-77 158 507 "SDE2,CSMD3,USP31,NLGN4X,SLC24A4,ZNF608,PCDH19,OSBPL6,PARG,APBB2,MIER1,STK33,MARK4,EIF4G3,ATP2B1,ATP2B2,ADGRB2,JAZF1,DLGAP2,CFL2,SOCS6,DNAJB5,PCYT1B,ACBD5,ZNF385A,PNKD,CTNND2,PPP6R2,RUBCN,DCAF8,IP6K1,DBN1,PLEKHM1,TIAM2,MAGI2,RHOBTB1,DLG2,GRIN3A,RAB39B,DMD,USP3,DNM2,DMTF1,DNAJB6,DYRK1A,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,EIF5,EN2,EPB41,EPHA5,ERBB2,ERBB4,PTK2B,SCML2,FGF12,FOXF2,NBEA,MSANTD4,OGA,RUNDC3A,TCERG1,TNRC6A,GRM7,CIT,LINGO1,KLF12,LRRTM3,ITPKB,JAK1,KCNJ10,MAT2A,MBNL1,CHIC1,MID1,XRRA1,RSPO2,MXI1,MYCN,NCAM1,ZC3H12B,NELL1,NEUROD2,NHLH1,NPTX1,HCN1,GPR137C,CNTN3,ANLN,C11orf49,PRRX1,POU3F2,PPP3CA,PKN2,MAPK9,PTPN13,RAB5B,DBX2,RGS7,SEC61A2,SLC25A36,KCNIP1,RYR3,SALL1,ATXN1,FAM19A1,FAM102A,PPP1R9A,CPEB3,MAGI3,CHD9,FNDC3A,WDR37,SLA,SLC1A2,RIMS1,FAM126B,SOX11,NPAS3,ITPRID2,SEPT8,RGL1,SYNE2,PLCB1,CAMSAP2,FBXW11,TBL1X,TCF4,SATB2,TCF12,PUM2,THRA,HEY1,ZFP91,RBFOX2,TPM1,NR2C2,PDSS1,TRPS1,AMOT,FLRT2,PLEKHH2,VLDLR,TBC1D15,REEP1,DPYSL5,SLC30A3,WNK1,CA10,EMSY,CSDE1,WIPF2,ADAMTSL3,FRMD6,DPF3" MicroRNA hsa-miR-520h:PITA hsa-miR-520h:PITA_TOP PITA 3.24E-79 1.82E-75 1.50E-78 1.39E-77 158 507 "SDE2,CSMD3,USP31,NLGN4X,SLC24A4,ZNF608,PCDH19,OSBPL6,PARG,APBB2,MIER1,STK33,MARK4,EIF4G3,ATP2B1,ATP2B2,ADGRB2,JAZF1,DLGAP2,CFL2,SOCS6,DNAJB5,PCYT1B,ACBD5,ZNF385A,PNKD,CTNND2,PPP6R2,RUBCN,DCAF8,IP6K1,DBN1,PLEKHM1,TIAM2,MAGI2,RHOBTB1,DLG2,GRIN3A,RAB39B,DMD,USP3,DNM2,DMTF1,DNAJB6,DYRK1A,CELSR3,KMT5B,PLXNC1,GOLGA7,EIF4G2,EIF5,EN2,EPB41,EPHA5,ERBB2,ERBB4,PTK2B,SCML2,FGF12,FOXF2,NBEA,MSANTD4,OGA,RUNDC3A,TCERG1,TNRC6A,GRM7,CIT,LINGO1,KLF12,LRRTM3,ITPKB,JAK1,KCNJ10,MAT2A,MBNL1,CHIC1,MID1,XRRA1,RSPO2,MXI1,MYCN,NCAM1,ZC3H12B,NELL1,NEUROD2,NHLH1,NPTX1,HCN1,GPR137C,CNTN3,ANLN,C11orf49,PRRX1,POU3F2,PPP3CA,PKN2,MAPK9,PTPN13,RAB5B,DBX2,RGS7,SEC61A2,SLC25A36,KCNIP1,RYR3,SALL1,ATXN1,FAM19A1,FAM102A,PPP1R9A,CPEB3,MAGI3,CHD9,FNDC3A,WDR37,SLA,SLC1A2,RIMS1,FAM126B,SOX11,NPAS3,ITPRID2,SEPT8,RGL1,SYNE2,PLCB1,CAMSAP2,FBXW11,TBL1X,TCF4,SATB2,TCF12,PUM2,THRA,HEY1,ZFP91,RBFOX2,TPM1,NR2C2,PDSS1,TRPS1,AMOT,FLRT2,PLEKHH2,VLDLR,TBC1D15,REEP1,DPYSL5,SLC30A3,WNK1,CA10,EMSY,CSDE1,WIPF2,ADAMTSL3,FRMD6,DPF3" MicroRNA hsa-miR-581:mirSVR_highEffct hsa-miR-581:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.17E-79 2.34E-75 1.93E-78 1.78E-77 209 893 "ACADM,CSMD2,ADCY2,BEND6,INTS2,NME5,WDR35,CC2D2A,DPP10,EP400,LCORL,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DGKD,APP,SHTN1,MIER1,SPTBN4,ARNTL,RGS20,ASPH,BRINP2,ATM,EIF4G3,TTLL9,SYNJ2,MTMR2,BTRC,CACNA1D,CACNB2,VSTM2A,NFS1,CCKBR,CDC27,LRRFIP1,JAM2,NRXN3,C4orf33,QKI,MAP4K4,CNGA3,ARHGEF6,CNR1,ARMC8,MYRIP,MROH8,TENM4,SEC24C,CSNK1E,SIPA1L1,NCAN,GREB1,USP6NL,CYBB,DCAF8,KIAA0513,KCTD8,IP6K1,PABPC5,RABGAP1L,TMCC2,GRIN3A,DSCAM,GOLT1B,EBF1,EDNRA,HIPK3,OPTN,FAM13A,SUGP2,KMT5B,AASS,ELAVL3,CALCRL,RCAN2,ENPP6,ABCA8,FABP7,SCML2,FCGRT,TACC2,SMC2,APOPT1,ZNF605,CELF1,DACH2,AP4B1,ZMAT1,GABRA1,ZNF559,DISC1,LRRC37A6P,PCDH17,KIRREL3,BRD8,GK,ZNF276,FERMT2,RAPGEF4,GRIA1,GRM1,PRDM5,GRM7,ARHGAP36,HMGCL,USP51,OPALIN,DHX35,ZNF385B,ITGAM,KCNA2,KCNC1,KCNJ3,KCNJ10,KCNJ16,KCNK1,KCNMA1,KCNN2,LAMP2,INSYN2,VWA5A,HECTD2,MAN2A2,MAT2A,MEIS1,CD200,NDUFA5,NFIX,TBC1D25,OCRL,PAH,PAK3,PBX1,PCDH9,BEST3,NALCN,FAM218A,ING3,RAB39A,MAPK10,DIRAS2,PTPRD,PTPRG,PTPRO,QDPR,CEP97,PBRM1,ZFHX4,FBXW7,ATP8B4,LRRK2,LGR4,ABCA11P,SCN2A,LRRTM4,LINC00461,TNFRSF19,SUPT20H,ZFP30,FBXO11,ZNF365,SLC1A3,FAM214B,SLC6A1,SEPHS1,ATF7IP,SNRPN,PALLD,UNC80,SON,MYT1L,SP4,UHRF1BP1L,DBNDD2,CDK19,SRPK2,TAB2,SSTR2,SS18,ZFR2,SYNE2,ARHGEF9,SYT1,ATMIN,ZFP90,WDR7,CCDC173,TIAM1,ERCC6L2,TRO,RUSC1,TMEFF2,TUBB1,USP1,MEAF6,CCDC14,VLDLR,ZNF708,ZNF138,ZNF195,STOX2,LINC00632,CAB39L,ST7,RNF170,MSRB3,NHSL1,FXR1" MicroRNA hsa-miR-1278:mirSVR_highEffct hsa-miR-1278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.60E-79 2.59E-75 2.13E-78 1.96E-77 200 820 "KCNH8,ACADM,SORCS1,BEND6,SLC44A5,GPR158,KLHL13,TXNDC16,CC2D2A,TAOK1,USP28,PHF12,TNRC6C,IGDCC4,ARRB1,CADPS,ZBTB10,EIF4G3,DPY19L3,ATP6V0A1,DST,SCAPER,PTBP2,RUNX1T1,CCNH,TMEM257,CDC42,SYNPR,NDST3,RAB28,MYL6B,QKI,ARHGEF6,COL4A5,SLC25A27,LETMD1,SLC4A7,RCHY1,RNF14,CS,OSBPL3,SIPA1L1,CTNND2,ST18,EDRF1,CCDC144A,DOCK4,FRMPD4,TBC1D5,LIN54,PITPNC1,DNAJC6,ZNF804A,MYEF2,TIAM2,ZC3H11A,CHRDL1,DLX1,DTNA,DNM1L,EDIL3,RASGRP1,KLHL5,YAF2,APH1A,PLEKHA1,TMEM35A,RTN3,EYA1,GMPR2,ABCA8,WAC,ACSL4,KAT8,POLR1B,FGF13,POLK,CAP2,IP6K2,PSD2,TACC2,SMC2,UFM1,TPK1,KHDRBS3,DACH2,ZNF512,DKK3,ATP8A2,KIAA1841,TUBGCP4,MSTN,PPARGC1A,RNPS1,GLS,TNRC6A,PCDH11X,ADGRA3,GRIA2,GRM3,HSP90AA1,CELF5,RBPJ,IL6ST,LRRTM3,JAK1,KCNJ3,KCNMA1,KIT,IPO5,LAMP2,LIMS1,ZNF667-AS1,MATN2,MEIS1,MOBP,ZNF92,NAP1L3,NEFM,NEUROD1,OTOGL,PDE3B,PDE4B,OLA1,NALCN,PIK3C2A,PURG,SCHIP1,POU3F2,PRKACB,CEP41,RELN,MDGA2,CNTLN,PTK2,PXK,PTPN13,TTC13,PPP2R3C,OXR1,ERI2,UBR7,RIT2,ZNF532,DCUN1D2,EXD2,ALG9,ROBO1,RPE,LRRK2,RTN1,SEMA6D,SCN2A,SUPT20H,ARX,DOCK10,FNDC3A,PAAF1,SEPHS1,CCDC88A,SLC12A2,SLC20A2,PALLD,MYO16,UNC80,TRERF1,SP4,KDM4C,MCF2L2,NPAS3,SRPK2,CLASP2,NKAIN2,ERBIN,STAU1,KANK1,NECAB1,PRRC2C,SYT4,POPDC3,ADGRL3,TCF12,HHIP,AKTIP,GZF1,UCHL1,CCDC14,NSD2,CLDND1,ZNF711,ZNF17,ZNF45,ANKS1B,PLPPR5,EMSY,MPPE1,PDSS2,ZNF248,CBLN2,GAN" MicroRNA hsa-miR-1301:mirSVR_highEffct hsa-miR-1301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-79 3.09E-75 2.54E-78 2.34E-77 208 886 "NBAT1,ARID1A,NDRG3,PWWP2A,TXNDC16,USP35,DPP10,ANK2,ANK3,MAP4K3,PPFIA1,IGDCC4,CDK13,DDX3Y,ATP1B3,ATP2B1,NOL4,DST,SYNJ1,SYNJ2,C5,CDK5R2,MAP7,CCNH,LARGE1,SRSF11,CHN1,SYNPR,FBXO7,C4orf33,MAP4K4,LY86,RTTN,MFSD4A,CREM,ABCG1,MROH8,PHACTR3,CFAP61,PHF19,ZFYVE16,LIN54,DBI,AIF1L,JAKMIP2,SNAP91,G3BP2,HS3ST2,USP3,DTNA,ECM2,ABCC9,EBF1,TSPAN5,ANKRD46,HIPK3,YAF2,PHF20L1,EPHB1,SRRM1,DENND4A,RTN3,DNAJC27,EXTL2,WAC,CEP78,TOMM40L,TESK2,FGF1,OLFM1,AMOTL2,SUCO,CAP2,SEMA6C,FLT1,JKAMP,DACH2,B3GAT1,FYB1,SDCBP2,HRASLS5,FAM120B,ZMYND11,DISC1,CPLX2,IGSF5,PPARGC1A,ZNF638,ZNF782,GPD2,GPM6B,GRM7,KAT7,LINC01551,SOX21,GUCY1B1,FRMD3,TNFAIP8L3,ARHGAP36,ZNF181,RAB41,C5orf24,LRRCC1,JAK1,KCNJ3,KHK,KIF5A,KLC1,STXBP5,PAXBP1,SMAD9,MAP2,MBNL1,MDM4,MSI1,ADAM22,MT1M,MYO7A,NBL1,NF1,HCN1,SETD4,RETREG1,FAM216A,ZNF426,DRAM2,PPP2R5E,RASGEF1B,LRRC49,GDPD2,CNTLN,PLPPR1,PTK2,TMEM260,FAM120C,SLC25A48,DBX2,RADX,SLC6A15,NUDT11,ROBO2,MRAP2,BAALC,ATP8B4,NCBP3,MIR124-2HG,ATXN2,SCN2A,SCP2,ELMOD1,TRIM46,SELL,RASA3,ITSN1,SH3GL3,MAGI3,FBXO11,ST3GAL3,NUBPL,SLA,SLC8A3,SLC12A2,SLC22A4,SMARCE1,RCOR3,MYT1L,SOX2,TEX2,TAB2,CLASP2,ZNF302,NXT2,MAPK8IP3,ELOVL4,SYNE2,SYT4,KLHL4,ANO4,SATB2,WASHC4,FRYL,TEK,DICER1,SIRT1,SLC44A1,MTMR14,TMOD1,CSMD1,TPM3,C9orf85,ZNF346,FNDC5,FRRS1L,VSNL1,ZBTB14,TRIM9,AGMO,SLC30A4,PMEPA1,EMSY,PRDM2,LMAN2L,HPS4,SNX27,PLSCR4,PHTF2,PRRT4,FAM198A" MicroRNA hsa-miR-599:mirSVR_highEffct hsa-miR-599:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.62E-79 3.16E-75 2.60E-78 2.39E-77 211 911 "ACADM,ABHD6,KLHL32,SORCS1,ERMN,SLC24A4,GPR158,AK2,OGT,PHF12,PPFIA1,MAGEE2,UPRT,LRRC4C,TMEM263,NUMB,EIF4G3,ATP1B3,STX16,RIPK1,ADAM23,TTLL9,LINC00847,MAP7,LRBA,CDH18,MAGI1,CHGB,CHN2,CASC2,B4GALT6,LSMEM2,EPS15L1,NRXN3,COG1,ABCG2,CNTFR,AKAP7,AKAP6,CNRIP1,CP,CLOCK,CRMP1,ANKRD44,TRIM69,CSF2RA,SEC24C,PDE4DIP,ERC2,CMTM5,LIN54,DAPK1,CEP170,RABGAP1L,ARRDC4,DYRK1A,SNX29,EDN1,FAM135B,SEMA3D,SUGP2,EML1,EPB41,RCAN2,LRRC17,TAOK3,TOMM40L,BAIAP2,HPCAL4,AGAP2,PSD2,SMC2,PDLIM5,KHDRBS3,BRSK1,CAB39,ILDR2,GAD2,BRPF3,ARPP21,ERAP1,TMEM8B,C15orf41,DISC1,KIAA1841,MYOZ2,ARFIP1,ADAM28,BRD8,COPS8,ZNF638,LUZP2,FERMT2,GPD2,PRUNE2,FUT10,RAPGEF4,ATP2B1-AS1,RFFL,PRDM5,C1orf94,SHISA6,IDH3A,LINC00667,IGF1,RBPJ,USP54,LIX1,KCNA2,KCNK2,KLRC2,STXBP5,MAP4,LYPLAL1,MBNL1,MBP,MOBP,MOG,CD200,MTTP,MXI1,LAYN,NEUROD2,NF1,SLC11A2,NTRK2,PCSK5,PDE1C,PDE3A,PDE4B,PDE4D,PIK3C2A,GPSM2,PMP2,PMP22,EPB41L4B,MAPK9,MAPK10,VPS13C,MDGA2,BDNF-AS,PTHLH,PTPRD,BSDC1,TTLL7,PBRM1,EXD2,CARF,NEK11,FBXW7,PTGR2,RTN1,LRRTM4,SLC30A10,ZFP30,SH3GL2,FERMT1,SHC4,SEC31A,SEPHS1,SORCS3,ANKRD36,RIMS1,SNCA,SNRPN,MYCBP2,CLASP2,LRRC4,SS18,FAM168A,PRRC2C,ARHGEF9,C3orf70,TACC1,FAM208A,UNC5D,ANO4,ATMIN,SATB2,ZEB1,TCF12,CLASP1,PCDHB3,MTMR14,NR2E1,HEY2,SYNPO2,AMACR,TRO,PPIL6,TMEFF2,SLAIN1,PITPNB,VSNL1,CLDND1,FMN2,MKRN3,ZNF138,ANKS1B,PRTFDC1,FIP1L1,LINC00632,WNK2,FAM13C,DOCK8,ST7,KAT6A,SMIM8,CAMK1G,JMJD1C,SPATA13" MicroRNA hsa-miR-17-5p:Functional MTI Functional MTI miRTarbase 5.63E-79 3.16E-75 2.60E-78 2.40E-77 242 1181 "RALGAPA1,ADAR,FMNL2,ADD1,FZD9,SORCS2,ZNF578,MARCH4,KIF6,SEMA7A,USP28,EPB41L5,GPAM,APP,ARHGAP5,CAPRIN2,EIF4G3,ATP1B3,ATP2B1,MTMR9,KIF1A,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,FOXK1,CANX,MAP7,FMNL3,ZBED1,DIS3L,CFL2,SOCS6,EPS15L1,ZFYVE9,CLU,QKI,BTF3L4,SLC4A7,RTTN,ACBD5,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,FEZ2,SOCS5,UBXN2A,DCAF8,KIAA0513,EARS2,DAPK3,SIRPA,DNAL1,YTHDC1,ELMSAN1,PLEKHM1,FBXL5,CEP170,SACS,RABGAP1L,SEC16A,USP3,MED12,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,OPTN,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,EPB41L2,ERCC2,ETV1,RTN3,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,FER,GTF2IRD2,POLR1B,SUCO,ANKFY1,ZBED3,USP16,PDLIM5,TPK1,OGA,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,GNAS,GPM6A,FUT10,RAPGEF4,NR3C1,CIT,MFSD2A,FICD,HAS2,HMGB1,HSP90AA1,ITPKB,JAK1,KCNB1,KCND3,KCNMA1,KIF5C,CAMK2N2,ARHGAP12,GPR155,NAT8L,MBNL1,CHIC1,SCAMP5,AFF1,SESN3,MXI1,NAP1L1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,PFKP,CCSER2,ZFYVE21,TMEM38A,ZNF426,MTRF1L,LRP12,KANSL1,PRKACB,PRKCB,MAPK9,VPS13C,SLC22A23,PXK,ZIK1,OCIAD1,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,ZNF532,ELP2,TMEM100,SYNDIG1,ATAT1,FOXRED2,ATXN1,DRAXIN,ATXN7,TMEM200C,TRA2B,HSPA4L,FAM102A,CHD9,WDR37,RUFY2,ELMO2,BTBD7,COA1,CMTR2,FAM126B,SON,SP2,SP4,EMC1,MYCBP2,NPAS3,POGZ,SMOC1,STAC2,GANAB,ANKRD12,CAMTA1,DNMBP,WWC1,TCF4,TCF7L2,PSD3,GPRIN3,ZMAT3,AKTIP,TMEM9,NACC2,TJP1,CBX5,DDHD1,PARD3,TPM4,RGMB,NR2C2,TSC2,UBC,VLDLR,TBC1D15,NSD2,ZNF70,SH3GLB2,DHX33,MAP3K12,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2,RNF146,LAS1L" MicroRNA hsa-miR-542-3p:mirSVR_highEffct hsa-miR-542-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.47E-79 4.20E-75 3.45E-78 3.18E-77 210 904 "RALGAPA1,TTYH1,SYS1,TKTL1,GPRIN1,KLHL32,KIAA1211,HECW2,WDR35,TAOK1,ALCAM,LCORL,PHF12,PPFIA1,LINC00173,MARCH3,ASPH,ATP1B3,ATP6V1G2,NRP2,ZNF599,PROM1,SCAPER,OSGIN2,IL33,DDR1,THSD7A,MAP7,COPB2,CHGB,CNOT8,FBXO7,TJP2,ABCG2,HECTD1,AKAP6,SUMF2,TBPL1,ZFP28,ANKRD44,CLIP3,CSNK1G3,RASGEF1C,CYBB,TOMM20,BRINP1,DBI,COPS7A,MAGI2,GSDME,SMG7,PLPPR4,SV2B,WDR20,DMD,DTNA,DNM1L,ABCC9,ANKRD46,EBI3,EGFR,ELAVL2,PAN3,ERCC2,RTN3,TLR7,MRVI1,F8,ZIC4,FCGR1A,FGF12,FGF13,SUCO,C2orf88,ZCCHC17,POMT1,UFM1,CELF1,SARAF,NRG3,PHYHIPL,AHCYL1,GALC,TUBGCP4,GLI2,MAP7D2,CECR2,STMN2,GRM5,KAT7,LINC01551,HPS5,NXPH2,HPSE2,HNMT,ZDHHC15,IGFBP1,DOCK7,LIX1,TUBB2B,ITIH2,KCNA1,KCNMA1,VWA5A,MARK1,MDM4,MID1,ZNF680,ZNF92,DDX25,P2RY13,NCAM1,NDUFA5,NOVA1,DNHD1,NTRK3,NUCB2,OCRL,GPR88,PFKFB3,CDK14,ANLN,XRN1,MTRF1L,MAPKAP1,STRN3,PRRX1,MAGEL2,PPM1B,PPP2R2C,EPDR1,MAPK9,GDPD2,ZSCAN32,ZNF615,PPP2R3C,REV3L,FIGN,RFX4,RGS3,EXD2,ROBO1,RORB,TMEM206,ELP2,ATP8B4,TRAPPC13,ATXN7,PRCD,ASRGL1,COPZ1,NLGN4Y,FNDC3A,FHOD3,R3HDM2,CNKSR2,SYBU,NUBPL,SLC8A1,SLC12A2,ZFP1,SORCS3,UNC80,BEX1,TAB2,COLGALT2,ZSCAN29,KLHL7,FGD4,ZFR2,ANKRD28,MCF2L,SATB2,CUX2,RPGRIP1L,TCF12,WDR7,SYNE1,DOCK9,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,TLR4,TPM1,NPL,TPM3,METTL3,TRIO,TSC1,TUBB1,BEST1,PCDH20,ZBTB14,ZNF189,ZNF225,EMSY,MFF,LMAN2L,ADAMTS9,LINC00632,PDSS2,PHTF2,JMJD1C,RNF170" MicroRNA hsa-miR-3190-5p:mirSVR_highEffct hsa-miR-3190-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.61E-79 4.28E-75 3.51E-78 3.23E-77 215 946 "ARID1A,ADORA3,OSBPL1A,KIAA1324,TAOK1,AMT,ANK3,PPFIA2,CNIH2,SUGT1P4-STRA6LP-CCDC180,PARG,TNRC6C,TMEFF1,MARK4,DACT3,TMEM108,ATP2B2,RAB29,WASF1,CACNB2,VSTM2A,ARHGEF2,LRRFIP1,LGI1,RCBTB2,NDST3,PPT2,MAP4K4,FHL5,ARMC8,BTF3L4,SLC4A7,IFFO1,CHD1L,GDA,CS,LRIG1,OSBPL3,CTH,EDRF1,ARHGAP24,ZFYVE16,SPOCK2,PITPNC1,ZEB2,HEPH,MAGI2,RHOBTB1,SV2A,AK5,TOM1,FCF1,PHF20L1,EGFR,PLEKHA1,ING4,TMEM35A,EMX2,EPHB1,ANKRD13B,CDHR1,SRARP,NRN1,EFEMP1,TESK2,FGF12,FGFR1,SEMA4D,NOP56,AKAP3,ZBED3,USP21,STAU2,FYB1,DKK3,GAD2,INPP5K,PPARGC1A,RND1,PCDH11X,ZNF638,KDM2B,LOXL3,GNAS,GNG3,WDFY3-AS2,TDRKH,RAPGEF4,GRM1,GRM5,ZNF496,COQ10A,HNMT,KCNK1,IPO5,STMN1,VWA5A,PACRG,CLEC18A,MARK1,WDR49,MOBP,MOG,CCDC80,MSI1,STK32C,MSR1,SCG3,MYO7A,NOS1,NOVA1,DNHD1,LRIT2,NPPA,CLEC9A,NTRK3,P2RX7,PCDH8,PCMT1,PCSK1,PDE1C,GDAP1L1,ZNF655,ZFYVE21,PLP1,MAPKAP1,MED1,HYDIN,CNNM2,ZNF844,OXR1,ARID4A,TRIM68,ERI2,RGS12,ZFHX4,RERGL,TMLHE,C12orf49,TMEM206,MRAP2,ATP8B4,LRRK2,RPS20,ATAT1,ZNF331,TMEM156,RMI1,S100B,SCN2A,ZFP2,TRIM46,SELL,ZNF821,SH3BP2,ITSN1,CCDC92,NLGN1,SEC31A,SLC12A2,ELMO2,BTBD7,NAXD,GKAP1,SORCS3,MYH15,MBD5,LMBRD1,SNRPN,RBM34,KIF1B,NPAS3,NFASC,TAB2,ADHFE1,VAMP1,DNAJC9,PLCB1,SLC37A2,ANO4,EHBP1,ZEB1,SYNE1,TNS2,MTMR14,TK2,DDHD1,TMOD1,R3HDM1,TNR,TP53BP2,CDK20,PRMT8,WNT7A,KCNT2,SLC26A10,TCEAL7,SH3GLB2,DHX33,ZNF225,PRDM2,HPS4,ITM2C,PCBP4,WNK3,PDSS2,EPM2A,SMIM8,FBXO36,CASC15,TIGD6,IFT88,NETO2,SLC4A10,SENP7" MicroRNA "TGAATGT,MIR-181B:MSigDB" "TGAATGT,MIR-181B:MSigDB" MSigDB 1.45E-78 8.17E-75 6.68E-78 6.16E-77 151 465 "CPNE2,SLC25A25,FMNL2,GALNT16,SLITRK1,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,DDX3Y,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,ADGRB3,HCN2,ARHGEF7,JAZF1,FOXK1,CACNB2,CAMK2G,CBFA2T2,LRBA,CACNA2D2,SYNPR,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,TOX,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,G3BP2,WDR20,ARNT2,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,EN2,NCALD,BAIAP2,CAMSAP1,MEX3B,SYT3,PDLIM5,GABRA1,GGT7,TCERG1,GLS,GRB10,GRIA2,GRIK2,NR3C1,GRM5,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,DOCK7,KCNMA1,IPO5,LMO1,MAPT,MAT2A,ADAM11,AFF1,MSI1,RSPO2,MYBPC1,MIR4697HG,SFR1,NOVA1,IGSF11,KCNK10,PRTG,PDGFRA,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CNTNAP3,ATXN1,SOX6,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,PALLD,TMCC1,USP33,DOP1A,SOX5,LMO3,SRPK2,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,GSE1,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,MEAF6,ZIC2,ZIC3,TRIM9,SPIRE1,RGMA,PAK5" MicroRNA "TGAATGT,MIR-181A:MSigDB" "TGAATGT,MIR-181A:MSigDB" MSigDB 1.45E-78 8.17E-75 6.68E-78 6.16E-77 151 465 "CPNE2,SLC25A25,FMNL2,GALNT16,SLITRK1,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,DDX3Y,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,ADGRB3,HCN2,ARHGEF7,JAZF1,FOXK1,CACNB2,CAMK2G,CBFA2T2,LRBA,CACNA2D2,SYNPR,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,TOX,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,G3BP2,WDR20,ARNT2,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,EN2,NCALD,BAIAP2,CAMSAP1,MEX3B,SYT3,PDLIM5,GABRA1,GGT7,TCERG1,GLS,GRB10,GRIA2,GRIK2,NR3C1,GRM5,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,DOCK7,KCNMA1,IPO5,LMO1,MAPT,MAT2A,ADAM11,AFF1,MSI1,RSPO2,MYBPC1,MIR4697HG,SFR1,NOVA1,IGSF11,KCNK10,PRTG,PDGFRA,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CNTNAP3,ATXN1,SOX6,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,PALLD,TMCC1,USP33,DOP1A,SOX5,LMO3,SRPK2,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,GSE1,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,MEAF6,ZIC2,ZIC3,TRIM9,SPIRE1,RGMA,PAK5" MicroRNA "TGAATGT,MIR-181C:MSigDB" "TGAATGT,MIR-181C:MSigDB" MSigDB 1.45E-78 8.17E-75 6.68E-78 6.16E-77 151 465 "CPNE2,SLC25A25,FMNL2,GALNT16,SLITRK1,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,DDX3Y,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,ADGRB3,HCN2,ARHGEF7,JAZF1,FOXK1,CACNB2,CAMK2G,CBFA2T2,LRBA,CACNA2D2,SYNPR,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,TOX,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,G3BP2,WDR20,ARNT2,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,EN2,NCALD,BAIAP2,CAMSAP1,MEX3B,SYT3,PDLIM5,GABRA1,GGT7,TCERG1,GLS,GRB10,GRIA2,GRIK2,NR3C1,GRM5,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,DOCK7,KCNMA1,IPO5,LMO1,MAPT,MAT2A,ADAM11,AFF1,MSI1,RSPO2,MYBPC1,MIR4697HG,SFR1,NOVA1,IGSF11,KCNK10,PRTG,PDGFRA,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CNTNAP3,ATXN1,SOX6,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,PALLD,TMCC1,USP33,DOP1A,SOX5,LMO3,SRPK2,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,GSE1,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,MEAF6,ZIC2,ZIC3,TRIM9,SPIRE1,RGMA,PAK5" MicroRNA "TGAATGT,MIR-181D:MSigDB" "TGAATGT,MIR-181D:MSigDB" MSigDB 1.45E-78 8.17E-75 6.68E-78 6.16E-77 151 465 "CPNE2,SLC25A25,FMNL2,GALNT16,SLITRK1,UNC5A,OSBPL8,OGT,CDC42BPA,DPP10,SEMA4G,DDX3Y,ATP2A2,ATP2B1,ATP2B2,RNF182,MTMR9,ADGRB3,HCN2,ARHGEF7,JAZF1,FOXK1,CACNB2,CAMK2G,CBFA2T2,LRBA,CACNA2D2,SYNPR,NRXN1,NMT2,QKI,NIPBL,CNR1,AKAP6,ABI3BP,TBPL1,SEC24C,OSBPL3,CSNK1G3,CNTNAP2,PUM1,GAPVD1,TOX,LONRF1,ELMSAN1,ZC3H11A,POM121,PLPPR4,G3BP2,WDR20,ARNT2,CDON,DPYSL2,E2F5,KLHL5,PHF20L1,MBNL2,EGR3,EN2,NCALD,BAIAP2,CAMSAP1,MEX3B,SYT3,PDLIM5,GABRA1,GGT7,TCERG1,GLS,GRB10,GRIA2,GRIK2,NR3C1,GRM5,ADAMTS6,BACH2,HLF,NEGR1,AGFG1,SOWAHA,DOCK7,KCNMA1,IPO5,LMO1,MAPT,MAT2A,ADAM11,AFF1,MSI1,RSPO2,MYBPC1,MIR4697HG,SFR1,NOVA1,IGSF11,KCNK10,PRTG,PDGFRA,ZNF655,CCSER2,LRP12,SCHIP1,EPB41L4B,ZNF615,FIGN,ROBO2,CNTNAP3,ATXN1,SOX6,DOCK10,CHD9,FBXO11,FNDC3A,WDR37,BTBD3,PKNOX2,CPEB4,PALLD,TMCC1,USP33,DOP1A,SOX5,LMO3,SRPK2,CAMTA2,LARP4,NKAIN2,KANK1,SEPT3,GSE1,MTCL1,TBL1X,TRIM2,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,NR2C2,MEAF6,ZIC2,ZIC3,TRIM9,SPIRE1,RGMA,PAK5" MicroRNA hsa-miR-595:mirSVR_highEffct hsa-miR-595:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-78 1.04E-74 8.49E-78 7.82E-77 195 786 "CLK4,ACTN1,CSMD3,PLEKHH1,BEND6,KIAA1324,CEP126,BCAR3,LCORL,MAP4K3,CACHD1,ZBTB10,ATP2B1,B3GALT2,BACH1,SYNJ1,CACNB2,KALRN,HIP1R,CCNH,USP6,RGN,INA,LGI1,TIGD7,CHM,CHN2,CNOT8,RAB28,NRXN3,TPP1,MAP4K4,BAG4,CREM,RGS6,MICAL2,PHACTR3,SLITRK5,PUM1,HDAC9,PITPNC1,ZEB2,HEPH,MYEF2,KIAA0753,GRIN3A,CPEB2,PDCD6IP,DNM1L,ABCC9,RBM12,MBNL2,PLEKHA1,C8orf37,GPHN,CEP85L,ADGRV1,SH3YL1,ACSL4,TAOK3,GORAB,FER,FGF12,BAIAP2,SUCO,FOXF2,SYNCRIP,SEMA4D,PSD2,NOP56,NELFCD,PDLIM5,OGA,GABRA1,GABRA2,BRPF3,ARPP21,NCKAP1,ERAP1,ZNF559,C15orf41,GHR,LYVE1,RAB30,GLS,WDFY3-AS2,GPR37,TMEM121B,DIDO1,HAS2,C1orf94,AGBL5,IGF1,PLD5,KCNC1,SYT9,MOBP,MOG,MOV10,BLOC1S2,RTL5,NCAM1,NEK1,VWA2,DNHD1,IGSF11,GPR88,OPHN1,PAH,GLIPR1L2,ETFRF1,PCMT1,PDE4D,GPR85,CDK14,ANLN,A2ML1,ST8SIA5,HMGCLL1,PDZRN4,PRRX1,NXPH1,MAPK10,ANKHD1,MTMR10,PTHLH,PTK2,ZIK1,PTX3,SLC25A48,FAM66C,ATG16L1,RBBP6,ZYG11B,GTDC1,ZDHHC4,RGS7,ATP8B4,STK32B,TRAPPC13,HES6,SGK1,KIF21A,SH3GL2,CPEB3,MYO18A,SYBU,SLC1A6,BTBD3,ZNF430,ARHGEF40,CCDC88A,CPEB4,SORCS3,SMARCE1,MBD5,SNRPN,DOK5,ATP10B,AJAP1,KLHL7,COBL,SATB2,CLASP1,FRYL,TEK,ITGB3BP,TGFBR3,HHIP,AKTIP,ZFP91,HEY2,NPL,TPM4,PRMT8,RUNDC3B,AMACR,CLHC1,UBTF,PITPNB,NSD2,CLDND1,ZIC3,ZNF74,MKRN3,ZNF138,STOX2,PRDM10,MDH1B,ZNF248,NHSL1,IFT88,RNF146,SLC4A10,SPATA13" MicroRNA hsa-miR-34c-5p:mirSVR_highEffct hsa-miR-34c-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.89E-78 1.06E-74 8.68E-78 7.99E-77 209 900 "ASIC2,SYS1,KDM5D,ADD2,ADRA1D,MTUS1,GPR158,HACE1,KIAA1324,LRRC7,ALCAM,DOC2A,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,VAT1L,TNRC6C,TMEFF1,NCOA1,B3GALT2,DPY19L3,ADAM23,BCS1L,SYNJ2,ARHGEF7,JAZF1,OSGIN2,WASF1,CALB1,KALRN,INA,DGKI,ZMYM4,EVI5L,LGI1,TIGD7,NUMBL,EPS15L1,RAB33A,TMEM59L,SULT4A1,HECTD1,AKAP6,SLC25A27,SLC4A7,MYRIP,CLIP3,TRIM69,LRIG1,SIPA1L1,CNTNAP2,ERC2,PNPLA8,CTNND2,ZSCAN23,NOS1AP,ZFYVE16,IST1,DGKB,BRINP1,GIT2,ELMSAN1,MAGI2,RHOBTB1,RCAN1,DNM1L,E2F5,SYT15,FAM13A,KMT5B,RGS17,TMEM35A,C8orf37,SIRPB1,NRN1,ACSL4,SUCO,HPCAL4,FOXG1,PSD2,SLC37A3,NOP56,ZCCHC17,GABRA3,BRPF3,ZMYND11,ARPP21,GHDC,MTHFD2,C15orf41,TUBGCP4,TUBA8,MSTN,LYVE1,LOXL3,GNAO1,GNAS,GOLGB1,CCDC184,GPR22,PCLO,GRID1,GRM7,NXPH3,ARHGAP36,IGSF1,LRRTM3,ITPKB,KCNA2,KCND1,KCND2,KCNK3,KIF5A,KIT,VWA5A,HECTD2,MDM4,KITLG,MYCN,NCAM1,CCDC13,NF1,NNAT,CNOT4,NTRK3,OPHN1,CDK18,PDGFRA,GPR85,GDAP1L1,CCSER2,ST8SIA5,JAKMIP1,PURG,STRN3,ING3,PKIA,SIDT1,CNTLN,MTMR10,PTHLH,PTPRD,EML5,PTX3,PEX2,PEX5,ZNF844,PPP2R3C,TMEM255A,FAT4,RAP1GDS1,SLC6A15,RIC8B,RNASEL,ZFHX4,SPIN3,TCP11L1,LGR4,SATB1,ATXN7,SCN2A,ELMOD1,ITSN1,RUFY2,KDM4D,SORCS3,DMRTC1,RIMS1,KIF13A,SNRPN,PALLD,PDZRN3,KIF1B,POGZ,ARHGEF9,SYT1,DDHD2,CAMTA1,FAM208A,ANO4,ATMIN,SATB2,RPGRIP1L,DOCK9,USP32P1,FRYL,AHCYL2,RNF216P1,ITGB3BP,TNR,TPD52,TRIO,TSN,TUBB1,CADM1,PLEKHH2,BCL2L13,SYNC,DHX33,LMAN2L,MDH1B,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-761:mirSVR_highEffct hsa-miR-761:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-78 1.13E-74 9.26E-78 8.53E-77 211 917 "KCNH8,ACLY,SYS1,KLHL32,BRAP,SORCS1,PWWP2A,RNF150,ADRA1D,AP2A2,INTS2,C1QTNF3,LRRC7,SPOP,FAM135A,ANK3,ALS2,PPP4R4,ASTN1,ATM,RGS9,CDK5R2,IL33,DDR1,CACNB2,LURAP1,CALB2,THSD7A,PTBP2,LRRFIP1,DLGAP1,SRSF11,RAB33A,PPT2,QKI,FAM149A,AKAP6,COL4A5,TBPL1,MFSD4A,ENTPD4,CS,SEC24C,LRRC3B,SOCS5,PHACTR3,CMTM5,PUM1,DCAF4,EDRF1,HDAC9,RIPOR2,KCTD8,DGKG,GIT2,JAKMIP2,ZEB2,MYEF2,COPS7A,C2CD2L,LYPD1,SV2B,SRGAP3,DMPK,ABCC5,E2F6,EBF1,SGK2,SEMA3D,YAF2,PHF20L1,ING4,RCSD1,F8,CLVS1,WAC,TAOK3,KAT8,FGF1,FGF14,FHL1,IP6K2,SYNCRIP,NELFCD,TMEM107,FAM49B,NPTN,CAMKK2,ATP2C1,ARPP21,ZNF274,NCKAP1,SULT1C4,GPR162,SESN1,AHDC1,USP19,LYVE1,DHRS4,PCDH11X,KCNMB4,GNAL,ZNF782,TDRKH,PCLO,GRIK2,GRM7,BTN2A1,FAM19A2,RNF165,PTPN5,COQ10A,RNFT2,SLC2A6,MAN1B1,SHISA6,MSL1,IGF1,ZIC5,KCNB1,KCNN1,KIF5A,KLRC2,MAP6,MITF,MT3,NINJ2,NNAT,VWA2,NOVA1,HCN1,NUCB2,IGSF11,LOC100128398,PAH,PBX1,PDE4A,PDGFRA,GPR85,ABCB1,NOMO2,FTO,HMGCLL1,SEPT4,PPM1B,SIDT1,QRICH1,BDNF-AS,PTHLH,PTH1R,TMEM260,PPP2R3C,PID1,TMEM255A,RAD51D,RAD52,OXR1,MRPS18A,RNASE1,SPIN3,ACER3,STK32B,SALL1,ATXN7,SCN3A,PRCD,TRA2B,NTNG1,CNKSR2,ST3GAL3,CLSTN1,ABLIM3,ZNF365,EPN2,DHX30,KDM4D,SLC8A1,SLC11A1,CPEB4,IFT122,ANKRD36,RBM34,MYT1L,DBNDD2,NPAS3,RGL1,NSFL1C,COBL,MMS19,KIAA1107,DMXL2,TPCN2,DOCK9,AHCYL2,SIK3,TEK,TIAM1,TPM3,FAM155A,UGT8,MEAF6,PCDH20,ANKS1B,SPIRE1,DHX33,PRDM10,PPP1R3F,PLSCR4,ZNF248,SLC4A10,GAN" MicroRNA hsa-miR-145-5p:TargetScan hsa-miR-145-5p TargetScan 2.10E-78 1.18E-74 9.62E-78 8.87E-77 179 663 "ABR,ACHE,CSMD3,FMNL2,ADD3,MTUS1,HECW2,OSBPL1A,FAM135A,OGT,EPB41L5,CACHD1,ASGR1,ATP1A2,N4BP2L1,DST,BSN,MYRF,CA12,CACNA1D,CACNB2,CABP7,CAMK2D,AIFM1,SCARB1,CDH2,CFL2,RAB3C,CLCN3,QKI,HECTD1,MAP4K4,PCYT1B,CABP1,BTF3L4,COX4I1,CREB5,AKAP12,APPL1,CTNND1,ARHGAP32,ARHGAP24,RASSF2,DNAL1,ELMO1,MAGI2,BLOC1S6,DDX46,MTX3,FAM107B,DLG4,DPYSL2,DSCAM,RCAN1,DYRK1A,EBF1,HIPK3,EFNA3,EFNB3,APH1A,ABI2,ELAVL4,GPHN,ERBB4,NCALD,ACSL4,CORO2B,DLC1,FER,FGF14,AMOTL2,PCYOX1,RGPD5,FLT1,ANKFY1,FUT9,ABLIM2,FYN,IGSF5,FAXC,GFRA1,FREM1,GGT7,LYVE1,KIAA1958,HTATSF1,OS9,KCNMB4,NUDT21,CECR2,GRB10,C1QL4,KIF3A,MFSD2A,BACH2,MIER3,GABARAPL2,NEGR1,AGFG1,HTR2A,KCNA1,KCNA4,KCNB1,KCNC2,KCNH1,KCNN3,PAXBP1,ARHGAP12,MDFI,LDLRAD3,MEIS1,MEST,MMP16,GIT1,SAMD5,CCDC80,BLOC1S2,MYCN,MYO5A,MYO6,NAP1L1,NFIA,HCN1,GPR137C,PCDH9,PCSK5,PDE3A,EPN1,PMP22,PSAT1,PPP3CA,PKN2,MAPK4,PRPSAP2,NWD1,REV3L,RFX3,RGS7,KLHL11,CCDC25,RORB,RTKN,CLIP1,ATXN2,KIF21A,PPP1R9A,CPEB3,NTNG1,FNDC3A,NLGN1,CPEB4,EPC1,RIMS1,PEG10,ARHGAP26,CLSTN2,LARP4,DIP2A,ANKRD28,MCF2L,CAMSAP2,KIAA0930,DOCK9,FAM189A1,PSD3,ARHGEF12,CRTC1,FRYL,ENHO,DOK6,CADM1,FLRT1,AGMO,GDPD5,NAV3,FAM47E,GOPC,RNF170,FXR1" MicroRNA hsa-miR-2355:mirSVR_highEffct hsa-miR-2355:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-78 1.19E-74 9.70E-78 8.93E-77 191 755 "CLK4,GALNT16,PWWP2A,KIDINS220,ZNF608,OSBPL1A,ALCAM,FAM135A,LRFN1,ZFAT,MYH7B,BCAS1,AQP4,TMEFF1,ASPH,CHRD,ADAM23,BACH1,ZNF599,GPC2,CA12,PTBP2,TRIM41,CAST,P2RX6,ZBED1,LARGE1,MAGI1,CDO1,RCBTB2,SRSF11,CHN2,IGFBP7-AS1,SLC4A8,ABI3BP,RNF14,CSNK1G3,PDE4DIP,CCDC144A,TMEM170A,AIF1L,ZNF804A,TIAM2,KIAA0319,ALKBH8,PARD6A,SV2A,KIF19,DTNA,EDN1,ANKRD46,EFNB3,PHF20L1,MBNL2,ELAVL3,EYA1,GMPR2,F5,WAC,DLC1,PPP1R1B,FGF11,BAIAP2,RGPD5,NBEA,PDLIM5,STAU2,ZNF512,GABRB3,AHCYL1,BRPF3,ARPP21,SALL3,MYOZ2,COPS8,POLL,WDFY3-AS2,CECR2,ATP2B1-AS1,NR3C1,FAM107A,ATXN2L,TNFAIP8L3,LINC01102,HAPLN2,SYNPO,HNRNPK,AGFG1,SHISA6,ZNF181,IL6ST,METTL21A,KCNA2,KCNB1,KCNJ3,MAG,ZFYVE27,MBD1,POC1B,MOBP,ADAM22,BCO1,MYO9A,NBL1,NDP,LRIT2,NPTX2,HCN1,NTRK3,OPHN1,PDCD2,PDE1A,PDE4D,PDE1B,PDGFRA,PIK3CD,PMP2,RETREG2,MAPK9,GRAMD1C,LAMA1,MDGA2,RAD51D,ZYG11B,RET,FIGN,RFX4,RLBP1,RNASEL,ELP2,TMEM100,LGR4,ABCA11P,ZNF354C,COPZ1,ASAP3,SLITRK3,WDR37,PPP4R3A,BTBD3,KANSL3,BTBD7,ATF7IP,EPC1,NAXD,RCOR3,LIMCH1,RIMS1,UNC80,SOX2,KDM4C,DBNDD2,SRPK2,POGZ,ZNF302,TTBK2,STAC2,FAM168A,RHBDL3,TACC1,ROBO3,SATB2,AKNA,FRYL,FAM200B,SIRT1,LEFTY2,MTMR14,TIE1,ERCC6L2,TMPO,SEZ6L,TPM1,METTL3,TRIO,TRPS1,LRTM2,RPL7L1,UBE3A,UGT8,RICTOR,ZNF138,SPIRE1,SYNC,EMSY,PRTFDC1,CIAPIN1,URM1,SLC17A7,ITM2C,MSRB3" MicroRNA hsa-miR-433:mirSVR_highEffct hsa-miR-433:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.90E-78 1.63E-74 1.33E-77 1.22E-76 227 1056 "CLK4,XKR4,CSMD3,KLHL32,DSCAML1,ADCY6,ADD3,INTS2,HECW2,NME5,WDR35,C1QTNF3,BCAR3,USP28,USP37,MIER1,ASPH,ZBTB10,TMEM108,STX16,B3GALT2,N4BP2L1,TTLL9,BARD1,MTMR2,C1QC,RAB29,REPS2,CDC27,LGI1,CHM,CHN2,MS4A7,IGFBP7-AS1,NRXN1,NMT2,CLTA,TMEM155,TOGARAM2,CNRIP1,CP,CPS1,FEZ2,CSNK1G3,SIPA1L1,NRSN1,GAPVD1,ARHGAP24,CENPL,ARMCX4,DNAJC6,MYEF2,HP1BP3,CEP170,RHOBTB1,SACS,WDR20,RAB39B,DMD,DNM1,CDON,ABI1,RCAN1,ARRDC4,ABCC9,WDPCP,RASGRP1,RBM12,KCTD3,COPS4,STARD3NL,DCTN4,EPHB1,ENPP6,RABEPK,DENND4A,CDKL3,TLR7,EXTL2,EZH1,ABCA8,ZNF461,RPS6KC1,ACSL4,FDFT1,PRKAG2,CAP2,COQ5,SMC2,ST6GALNAC3,STAG2,GALC,SALL3,GAP43,DISC1,NEU3,PPARGC1A,RAB30,TOX3,POLL,RAB40B,FERMT2,GPD2,GPR12,EML4,GRIA2,NR3C1,PSIP1,NXPH2,AGBL5,HNMT,SMAP1,HTR5A,IGFBP1,IL12A,LRRTM1,ITGAV,ITPKB,JAK2,KCNJ16,KCNMA1,KIF2A,KPNA5,VWA5A,MAOB,MAP4,LYPLAL1,MARK3,WDR49,SESN3,MSR1,MXI1,MYO9A,NAP1L1,NF1,OCRL,GPR137C,PRTG,GPR85,PURG,SLC36A4,NXPH1,MED1,PPP3CB,PRKACB,MTMR10,PTHLH,ELOVL2,PTK2,PXK,TTC13,ZNF844,TMEM255A,RAP1GDS1,RET,GTDC1,MRPS18A,SEC61A2,RIC8B,CCDC82,CARF,ROBO1,ROBO2,FBXW7,ACER3,ABCA11P,CLIP1,ZNF354C,ZNF568,SATB1,CSRNP3,SCN8A,SELL,KIF16B,MAGI3,CHD9,CTXN2,SNRPN,PDZRN3,BDP1,EMC1,KIF1B,ZNF302,KLHL7,VPS13A,FNDC9,ANKRD12,CAMTA1,FAM208A,ADGRL3,SATB2,ZEB1,TEK,PMS2CL,ITGB3BP,ARL10,MTMR14,TJP1,TMPO,FAM124A,C9orf85,PRMT8,RUNDC3B,ZMYND8,PPIL6,TSC1,RPL7L1,FAM155A,PLEKHH2,BCL2L13,VLDLR,ZNF781,SLC13A3,TRIM9,GPR158-AS1,LYPD6,POLR3H,EMSY,STMN4,PCDH15,CAB39L,PARP11,MARCH8,CASC15,SSPN,GAN,FAM198A" MicroRNA hsa-miR-150:mirSVR_highEffct hsa-miR-150:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.98E-78 1.67E-74 1.36E-77 1.25E-76 196 796 "ACADM,NCKAP5,SYS1,PWWP2A,LRFN2,KCTD16,TBC1D14,FAM135A,CNIH2,PPFIA1,PKP4,APC,EPB41L5,PHYHD1,API5,PPFIA3,DDX3Y,TMEM108,ZNF582,B3GALT2,ADAM23,CFLAR,CACNA1G,CACNA1D,CACNA2D1,PTBP2,CANX,CAST,RUNX1T1,CERS5,CD38,CDC27,ZMYM4,DLGAP1,RAB3C,IGFBP7-AS1,COG1,FAM149A,AKAP6,SEC31B,HINFP,FEZ2,MICAL2,SUSD5,PDE4DIP,CTH,RIMS2,KATNAL2,IST1,ARMCX4,FBXL5,SV2B,DMTF1,DYRK1A,USH1C,PHC2,APH1A,KMT5B,PLXNC1,GOLGA7,KCTD3,EIF5,PLEKHA1,ING4,C3orf18,OLIG2,EPB41,DENND4A,MRPL10,CLVS1,FAM198B,WAC,ACSL4,PTK2B,FCGRT,FER,GTF2IRD2,CAMSAP1,NBEA,SMC2,SPECC1,ATP6V1H,CELF1,DACH2,GAA,GABBR1,GABRB1,GABRG2,GAP43,SULT1C4,PPARGC1A,GLS,TNRC6A,MAP7D2,CCDC184,RASSF8,KLF12,NEGR1,IRF8,IFI16,C2orf72,IGSF1,SCIN,KCNB1,KCND1,KCNJ3,IPO5,LIMS1,VWA5A,PIK3AP1,MBD1,MDM4,COL28A1,NCAM1,NFE2L2,NRCAM,PCSK1,PDPK1,FTO,SMIM7,RC3H2,PRKACB,PROX1,MASP1,GON4L,CNTLN,PTPRE,PTPRH,MARCH1,CEP97,ZCWPW1,RASGRF2,TRIM68,RGS12,RNASEL,CCDC25,RORB,MRAP2,NEK11,SPIN3,ZC3H14,ACER3,KCNIP1,ZNF331,SCP2,ZFP30,FAM102A,SHC4,ST6GAL1,NUBPL,WDR37,ABLIM3,SLA,SLC1A6,DHX30,SLC8A1,SLC20A2,SMARCE1,FNBP1,ERC1,STOX1,CEP68,FGD4,VPS13A,SYP,SYPL1,COBL,DDHD2,FAM208A,ZEB1,WASHC4,DOCK9,TEK,HEY2,TMOD1,TPM3,ZNF384,SMUG1,RUNDC3B,TRPS1,RPL7L1,OSBP2,MTCH1,CLDND1,ZNF711,TRIM9,ZNF138,SLC17A7,HRASLS,AMN1,DOCK8,UBE3B,PHTF2,RNF146,CBLN2,GAN" MicroRNA hsa-miR-1200:mirSVR_highEffct hsa-miR-1200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-78 1.76E-74 1.43E-77 1.32E-76 204 861 "SYN3,AS3MT,XKR4,PTCHD1,INTS2,MTUS1,OSBPL8,CC2D2A,ZNF687,APBA2,BCAS1,CDK13,NCOA1,SLC2A11,DOCK11,RGS9,NRP2,C5,CACNA1E,KALRN,CAPN3,VSTM2A,CARS,CBR1,INA,CDH10,L3MBTL4,MAGI1,CDR1,TIGD7,CHM,NDST3,PPT2,ABCG2,LETMD1,IGDCC3,CPS1,CREM,RBM39,ANKRD44,CS,CSF2RA,FEZ1,CST3,PHF14,CFAP61,CTNND2,ZSCAN23,DCAF4,EDRF1,TCAF1,ZFYVE16,CENPL,ARMCX4,PITPNC1,ZEB2,HEPH,EXOG,USP3,ARRDC4,DTNA,ABCC5,ABCC9,E2F6,WDPCP,SYT15,YAF2,PHF20L1,COPS4,PLEKHA1,EML1,LRRC17,SRRM1,IGSF6,NRN1,ABCA8,CACNG3,TAOK3,TOMM40L,STRADA,ZNF589,GTF2IRD2,FGFR1,CAP2,ATP13A4,TMEM107,KHDRBS3,HHIPL1,AP4B1,GAA,GAB1,NEU3,GCK,SULT1C4,TXNL4A,TNRC6A,PCDH11X,CBX1,LNX1,TDRKH,EML4,PCLO,STMN2,ATP2B1-AS1,GRIA2,ZBTB49,LINGO1,FRMD5,BACH2,AGBL5,HNF4G,DHX35,HSPA1L,SLC35G1,KCNMA1,KLC1,HECTD2,NCOA7,MARK1,MIA2,POC1B,MMP16,ERICH3,SCG3,MTR,LYRM9,P2RX7,PDE3B,PDPK1,DUSP26,NALCN,HMGCLL1,EPB41L4B,POLR2F,CNNM2,APTX,PTK2,TMEM260,OCIAD1,TUG1,CEP97,RAP1GDS1,OXR1,FIGN,KCTD17,ZFHX4,CCDC82,ELP2,ZC3H14,LGR4,SALL1,ASIC4,TRA2B,KIF21A,PPM1E,KIF16B,NTNG1,FBXO11,PAAF1,FAM81A,SLC14A1,ZNF667,SMARCE1,ANKRD36,UNC80,USP33,BDP1,GLT8D1,CAND2,MYCBP2,KDM4C,ATP10B,LARP4,STAC2,ADHFE1,NECAB1,VPS13A,POPDC3,DNMBP,CAMSAP2,SATB2,ZEB1,WASHC4,DOCK9,TMEM121,CRB1,AP4E1,TIE1,ERCC6L2,TRO,DCBLD1,TSN,RFTN2,ZNF610,PITPNB,LAT2,XRCC4,ZIC3,ZNF19,TRIM9,PLPPR5,WNK1,ADAMTS9,FAM13C" MicroRNA hsa-miR-511:PITA hsa-miR-511:PITA_TOP PITA 3.94E-78 2.21E-74 1.80E-77 1.65E-76 157 508 "DPF1,CSMD2,ARID1A,ADCY6,ERMN,NLGN4X,HECW2,PCDH19,ADGRF5,SEMA6A,ALCAM,BEGAIN,LRRC4C,CDK13,DDX3Y,EIF4G3,ATP2B1,ATP2B2,MAP7,RUNX1T1,LDB2,USP6,CDH2,FOXN3,NRXN3,CLCN4,NRXN1,CLTC,QKI,MAP4K4,ZNF521,TENM4,CSNK1G3,ATRNL1,PHACTR3,ST18,DCAF8,FRMPD4,DNAJC6,MYEF2,SMG7,SRGAP3,DLG2,DLG3,RAB39B,FAM135B,RASGRP1,FAM13A,MBNL2,ABI2,EGR3,PLEKHA1,ELAVL3,CALCRL,PAN3,DCTN4,EMX2,GPHN,ERBB4,EYA1,MRVI1,FGF13,CAMSAP1,PSD2,AFF2,AKAP3,TACC2,KHDRBS3,CELF1,TPPP3,GAD2,MSTN,AHDC1,GFAP,GFRA1,PPARGC1A,SPIN1,TNRC6A,GLUL,EML4,HAS2,BACH2,HLF,HMGCR,NEGR1,C5orf24,KCNA1,KIF5C,CYP27C1,KTN1,MAP2,MBNL1,MEIS2,MITF,AFF1,CCDC80,MXI1,MYO6,NEUROD2,CNOT4,CDK14,CCSER2,NXPH1,PPP2R5C,PPP2R5E,PKN2,TMEM104,QRICH1,RAP1GDS1,ARID4A,KHDRBS2,REV3L,ZNF532,DCUN1D2,ROBO2,ZC3H14,RIMKLA,STK32B,HUNK,ATXN1,NLGN4Y,WDR37,SORCS3,ZCCHC24,HECW1,ARHGAP26,CDK19,RBM26,TAB2,CLASP2,POGZ,EPB41L3,LRRC4,SS18,ERBIN,RGL1,PHLDB1,ANKRD28,CAMTA1,AGTPBP1,EHBP1,SATB2,DOCK9,FRYL,TGFBR3,LRRC8A,FNDC5,UBE2H,FLRT2,REEP1,PMEPA1,CADM2,STOX2,PARP11,ADAMTSL3,VANGL2,FAM181A" MicroRNA hsa-miR-3175:mirSVR_highEffct hsa-miR-3175:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.86E-78 2.73E-74 2.22E-77 2.04E-76 213 938 "CPNE2,SERPINA3,CLK4,KDM5D,ADCY2,CCDC85A,ADD2,ADORA3,DPY19L2P4,SNX32,SEMA6A,SPOP,TNRC6C,CDK10,RGS20,LINC00173,DACT3,CCAR2,ATP2B1,SLC2A11,DPY19L3,CARMIL3,MPDZ,C1QC,MMD2,KALRN,SYT6,CAST,INA,PPT2,NRXN1,ABCG2,DNAJB5,CCDC151,CNTN1,ARMC8,SUMF2,COL9A2,CPS1,PNKD,GDA,VCAN,SLITRK5,DZIP3,GREB1,CFAP61,CTNND1,NRSN1,TCAF1,ZNF337,TMEM170A,SPOCK2,MAGI2,SMG7,SPOCK3,SV2A,NYAP1,DOCK2,DTNA,DTNB,FIS1,SEZ6L2,PHC2,EFNB3,APH1A,BSCL2,TMEM35A,PAN3,ENO2,ERBB2,EFS,ANKMY1,SIRPB1,ZNF461,PTK2B,KAT8,FGF1,FGF12,POLK,AKAP3,NPTN,NSG2,NEURL4,MEGF11,GABRA3,BRPF3,B4GALNT1,MTHFD2,LRRC37A6P,GLDC,SPIN1,LOXL3,GPD1,PRLHR,CCDC184,PLCD4,CLASRP,RNF165,UBE2QL1,SHISA6,IDH3B,RAB41,NME9,SLC35G1,KCNK2,KCNN3,CREG2,CAMK2N2,STMN1,MARK1,AFDN,MOBP,GIT1,MT3,LAYN,FXYD7,NNAT,NOVA1,OGG1,CLDN11,CDK18,PDE1B,GDAP1L1,PLP1,PCDH18,SCHIP1,C19orf57,POU3F2,PRKACB,KLK6,MDGA2,QRICH1,PTHLH,PTPRH,PLEKHB2,RAP1GDS1,BSDC1,PRRT2,MORC4,SEC61A2,RPRD1A,SUGCT,SETD5,C12orf49,CCDC102B,SPIN3,ADAL,TCP11L1,CLIP1,SEMA6D,SCN2B,ASIC4,SOX6,TRA2B,PPM1E,ARX,FERMT1,NTNG1,SHC4,FBXO11,DHX30,PKNOX2,SLC11A1,ELMO2,SLC22A4,SORCS3,SMARCD3,RIMS1,SNCB,SON,FNBP1,ZSWIM8,UHRF1BP1L,TSPYL2,C11orf87,ATP10B,POGZ,STAU1,ELOVL4,GANAB,STXBP1,FAM168A,SYN2,SYT4,UNC5D,WSCD1,TPCN2,PCDHB4,OBSL1,ZMAT3,AKTIP,ZNF384,NUTM2A,SSBP2,UBE3A,UBTF,UCHL1,OSBP2,MEAF6,NSD2,SF1,FMN2,SYNC,SLC30A3,SLC17A7,PPP1R3F,PCBP4,WNK3,PHTF2,TRAM2-AS1,PIANP,NETO1,JPH3" MicroRNA hsa-miR-187*:mirSVR_highEffct hsa-miR-187*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.49E-78 3.08E-74 2.50E-77 2.30E-76 201 839 "RALGAPA1,CLK4,NCKAP5,AXIN2,KIAA1211,BEND6,INTS2,RTL9,LRRC7,SPOP,BBOX1,AMPH,PHF12,SUGT1P4-STRA6LP-CCDC180,ANXA7,VAT1L,SHTN1,MIER1,SEMA4G,IGDCC4,RGS20,ASPA,ASPH,ATM,SLC4A4,ATP6V1G2,BLM,SCAPER,MMD2,DDR1,CALB1,CANX,SYNGR3,C1orf52,CDC27,CDH2,DCLK1,NUMBL,CFL2,CHGB,CHN1,CASC2,SYNPR,NDST3,NRXN3,ABCG2,MAP4K4,BTF3L4,SLC4A7,HS3ST5,CP,C2CD2,CREM,CRHBP,FEZ2,SIPA1L1,SOCS5,PLXNA4,SLITRK5,ERC2,PUM1,CCDC144A,TOX,MAML1,ZEB2,MAGI2,SACS,SPOCK3,CHRDL1,DYNC1I1,CASP8AP2,RCAN1,GOLT1B,PHC2,TMTC1,YAF2,FAM13A,PLEKHA1,C8orf37,EPHB1,DENND4A,ANKMY1,FAM198B,WAC,TMEM132C,FCGR3A,GTF2IRD2,KIAA1109,FGF14,UBE2E3,MEX3B,SYNCRIP,ANKFY1,NBEA,USP21,SARAF,GABRB1,SALL3,RNPS1,PCDH11X,GNAO1,GPM6A,FUT10,GRIA2,FAM19A2,ZBTB49,PSIP1,IRAK3,RASSF8,MIER3,AGBL5,MSL1,RBPJ,BRINP3,INSM1,ZNF385B,ARHGAP12,C2orf80,MARK1,CD200,ADAM22,CNOT4,PCDH9,PDGFRA,PFKFB2,OLA1,NOMO2,PIK3CD,PLCL1,MAPKAP1,SCHIP1,PPP2R5C,PPP3CB,CNTLN,PTK2,ZIK1,PTPRZ1,RAB3A,KHDRBS2,BSDC1,SLC6A15,RFX3,RGS4,RGS7,RGS10,SLC25A36,ALG9,RAVER2,RORB,STK32B,ATAT1,AP1AR,SAFB,ATXN2,LINC00461,FNIP1,HES6,SMPD3,FBXO11,BTBD3,SEPHS1,CPEB4,ZFP1,SNAP25,TMCC1,MYO16,MYT1L,BDP1,FNBP1,SP4,ZBTB43,MCF2L2,LMO3,SMOC1,ST5,EHBP1,TCF7L2,SZT2,FRYL,CCDC173,DICER1,AP4E1,TMPO,KAT6B,TP53BP2,TPM3,SYNPO2,RPL7L1,PITPNB,OSBP2,ZNF19,TRIM9,LYPD6,FSTL5,CADM2,PRDM2,FZD3,UBE3B,HNRNPA3,NLRP3,SENP7" MicroRNA hsa-miR-33b-5p:TargetScan hsa-miR-33b-5p TargetScan 6.02E-78 3.38E-74 2.74E-77 2.52E-76 140 399 "ABR,CCDC85A,ADD1,ADD3,BEND6,KCTD16,PCDH10,CDC42BPA,DPP10,ANK3,PHF12,LRRC4C,NCOA1,BACH1,DST,LDLRAD4,CACNA1D,CACNA1E,CAMK2G,RUNX1T1,DLGAP2,CLGN,CHN2,KIAA1549L,NRXN1,DNAJB5,QKI,MAP4K4,AKAP12,ANKRD44,CS,SEC24C,SDC3,RIMS2,CCDC144A,DCAF8,KIAA0087,DDX46,GRIN3A,HS3ST4,CALN1,CPEB2,RCAN1,EBF1,EDNRB,CNNM1,ABI2,RGS17,EN2,CEND1,ATP8A1,FGF12,FGF14,PNMA2,FYN,GABRA4,AHCYL1,NCKAP1,MTHFD2,GBX2,GHR,RAB30,GPR37,GRIK2,GRM8,RNF165,LINGO1,RASSF8,HAS2,BACH2,HMGCR,RAB41,PLD5,SCIN,KCND3,KCNK1,NCOA7,MDM4,MEIS1,MEIS2,MMP16,NFIA,NFIX,NOVA1,HCN1,GPR88,PDE3A,PDE3B,PDE4D,PDGFRA,PDPK1,NOMO2,FTO,PCDH18,PACSIN1,MAPK8,MDGA2,RFX3,ROBO2,RORB,HUNK,SALL1,CSRNP3,SCN8A,CASC3,GALNT10,PPP1R9A,CPEB3,NLGN1,FAM81A,BTBD3,CPEB4,FAM126B,MYT1L,HECW1,ERC1,KIF1B,IQSEC2,LRRC4,GSE1,ANO4,SATB2,RPGRIP1L,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RIMBP2,CSMD1,KAT6B,REEP1,CADM2,RGMA,EVI5,NAV3,HNRNPA3,MSRB3" MicroRNA hsa-miR-33a-5p:TargetScan hsa-miR-33a-5p TargetScan 6.02E-78 3.38E-74 2.74E-77 2.52E-76 140 399 "ABR,CCDC85A,ADD1,ADD3,BEND6,KCTD16,PCDH10,CDC42BPA,DPP10,ANK3,PHF12,LRRC4C,NCOA1,BACH1,DST,LDLRAD4,CACNA1D,CACNA1E,CAMK2G,RUNX1T1,DLGAP2,CLGN,CHN2,KIAA1549L,NRXN1,DNAJB5,QKI,MAP4K4,AKAP12,ANKRD44,CS,SEC24C,SDC3,RIMS2,CCDC144A,DCAF8,KIAA0087,DDX46,GRIN3A,HS3ST4,CALN1,CPEB2,RCAN1,EBF1,EDNRB,CNNM1,ABI2,RGS17,EN2,CEND1,ATP8A1,FGF12,FGF14,PNMA2,FYN,GABRA4,AHCYL1,NCKAP1,MTHFD2,GBX2,GHR,RAB30,GPR37,GRIK2,GRM8,RNF165,LINGO1,RASSF8,HAS2,BACH2,HMGCR,RAB41,PLD5,SCIN,KCND3,KCNK1,NCOA7,MDM4,MEIS1,MEIS2,MMP16,NFIA,NFIX,NOVA1,HCN1,GPR88,PDE3A,PDE3B,PDE4D,PDGFRA,PDPK1,NOMO2,FTO,PCDH18,PACSIN1,MAPK8,MDGA2,RFX3,ROBO2,RORB,HUNK,SALL1,CSRNP3,SCN8A,CASC3,GALNT10,PPP1R9A,CPEB3,NLGN1,FAM81A,BTBD3,CPEB4,FAM126B,MYT1L,HECW1,ERC1,KIF1B,IQSEC2,LRRC4,GSE1,ANO4,SATB2,RPGRIP1L,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RIMBP2,CSMD1,KAT6B,REEP1,CADM2,RGMA,EVI5,NAV3,HNRNPA3,MSRB3" MicroRNA hsa-miR-514:mirSVR_highEffct hsa-miR-514:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.87E-78 3.86E-74 3.12E-77 2.88E-76 201 840 "KCNH8,SLC25A25,SORCS1,ERMN,PWWP2A,KIDINS220,USP28,AMER3,PPFIA3,CDC14B,PLA2G4C,MARK4,NCOA1,BACH1,ADGRB3,SEC11C,JAZF1,CBFA2T2,CLGN,CHN1,CHN2,TAOK2,RAB28,NRXN3,FAM149A,BTF3L4,MYRIP,TRIM69,CSNK1G3,ATRNL1,FAM169A,CFAP61,NRSN1,HDAC9,KIAA0586,DGKB,MAGI2,SMG7,SV2B,RABGAP1L,NR1D2,ABI1,GNE,ABCC9,GOLT1B,E2F6,EDIL3,EGFR,ELAVL4,PCOLCE2,EPS8,AMZ2,FABP7,SUCO,CAP2,SYNCRIP,FLT1,SLC37A3,ARFGAP2,DACH2,NSG1,TVP23A,PHYHIPL,GAD2,B4GALNT1,SULT1C4,GLI2,INSM2,DCLK2,LPAR4,GRIA2,GRIK2,GRIK4,NR3C1,GRM8,RASSF8,HMGCR,ZNF491,CELF5,FAAP20,IDH3B,LRRTM3,JAK1,SLC35G1,KCNB1,KCNJ11,KCNK2,KLC1,LIG4,HECTD2,NCOA7,MATN3,MEIS2,POC1B,AFDN,SESN3,ADAM22,RSPO2,MXI1,IDNK,NNAT,NRCAM,PCSK5,PDE3B,SSH1,PLCL1,STRN3,SPATA6,TATDN3,SLC26A11,GRAMD1C,HYDIN,PTHLH,TMEM260,OCIAD1,EML5,PTPRG,PTPRZ1,RAB3A,SUSD4,NWD1,ENOX1,KHDRBS2,RFX3,SLC25A36,TMLHE,CCDC102B,BAALC,ZC3H14,RTN1,SCN3A,LRRTM4,SCN8A,PEAR1,TRIM46,DOCK10,NTNG1,FNDC3A,SEC31A,ZNF365,SEPHS1,RAB3GAP1,NAPB,NAXD,ZNF667,TTC17,UNC80,SON,BDP1,SPP1,ERC1,NPAS3,ITPRID2,SULF2,SYT11,ARHGEF9,VPS13A,C12orf76,TAC1,CAMSAP2,TBCEL,SIN3B,TCF7,TCF12,WASHC4,USP22,SZT2,PCDHB6,TEK,DICER1,ITGB3BP,CDH22,NACC2,C5orf64,TPM1,ZNF346,METTL3,STXBP4,ANO5,TTTY15,CADM1,EIF4ENIF1,UGT8,RBFOX3,PORCN,ETNPPL,LYPD6,ZNF142,FSTL5,EML6,ZNF189,PLPPR5,SYNC,SLC30A4,MDH1B,NAV3,KCNAB1,MVB12B,HNRNPA3,RNF170,NETO2" MicroRNA hsa-miR-3137:mirSVR_highEffct hsa-miR-3137:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-77 5.73E-74 4.63E-77 4.27E-76 179 669 "ADAR,KIAA1211,BEND6,SNX32,FAM135A,ZFAT,PKP4,APC,UPRT,ALS2,APOC1,TMEM263,RASL11B,NOL4,ADAM15,SYNJ2,CACNB2,VSTM2A,CAST,INA,CDC27,NOG,CIART,SRSF11,CLTA,CNGA3,TMEM155,COL9A3,TBPL1,CHD1L,SEC31B,PREPL,CREM,ATRNL1,SOCS5,PDE4DIP,CYBB,KIF26A,TMEM170A,PABPC5,PLPPR4,USP3,DMTF1,DRD1,ABI1,DYRK1A,GOLT1B,EBF1,WDPCP,ATL1,SGK2,FSD1L,FAM13A,EIF1,TUBD1,EPHA5,KCNMB2,GPHN,FCGR1A,SUCO,HPCAL4,IQCG,FLT1,NPTN,ZNF605,STAG2,DKK3,GALNT15,GABRG2,GALC,DISC1,KIAA1841,MSTN,GDF9,GNAS,GRIA2,DIDO1,GRIA4,LINC01089,GUCY1A2,RASSF8,NXPH2,ELOVL5,ICA1,ZIC5,IGSF1,IL6ST,KCNA4,KCNJ10,KHK,CYP27C1,MAT2A,SRSF12,MID1,PPM1L,XRRA1,ERICH3,ADAM22,MXI1,NF1,CLEC9A,NUCB2,ZNF827,CDK18,SEMA5B,ANLN,PIK3R1,A2ML1,PRIMPOL,NXPH1,DRAM2,PPP2R2B,CRLS1,RASGEF1B,GRAMD1C,HYDIN,DIRAS2,SIDT1,SNRK,MTMR10,PTHLH,PTPRD,PEX5,TMEM255A,ENOX1,OXR1,SEC61A2,TMLHE,CARF,RORB,TMEM206,MRAP2,NEK11,ZNF331,ATXN7,SCP2,ASIC4,ZFP2,HSPA4L,SH3GL3,FBXO11,ZNF365,SORCS3,ANKRD36,KDM4B,MYT1L,KIF21B,ZNF423,C3orf70,CAMTA1,ANO4,WDR7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TGFBR3,ERCC6L2,TP53BP2,TPD52,HSPBP1,TMEFF2,PITPNB,TOM1L2,LAT2,ZIC2,TRIM9,PLPP4,SLC38A1,LINC02210,STOX2,PLSCR4,PDSS2,FXR1,NETO1,SENP7" MicroRNA hsa-miR-1237:mirSVR_highEffct hsa-miR-1237:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.47E-77 8.23E-74 6.65E-77 6.12E-76 198 819 "NCKAP5,ACTN2,KDM5D,PWWP2A,RNF150,ESYT2,ADRB2,TBC1D14,SPOP,BCAR3,FAM135A,OGT,ANK3,CNIH2,FAM131A,PHYHD1,USP37,TMEM263,ASTN1,EIF4G3,ADAM23,TTLL9,BBS2,BCHE,GYG2,CACNB2,KALRN,HIP1R,DGKI,CDC27,LGI1,NIPBL,PICK1,IQCK,FAM149A,SLC4A8,AHCTF1,ANKRD44,GDA,TENM4,PDE4DIP,CTH,GREB1,PPP6R2,CYBB,KATNAL2,ARHGAP24,DCC,PITPNC1,SPATA2,ZBTB24,HEPH,MYEF2,B3GAT3,FBXL5,SMG7,PLPPR4,G3BP2,WDR20,DMD,DMTF1,ABCC5,EDNRA,SEMA3D,RBM12,KCNMB2,RABEPK,SIRPB1,NSRP1,RPS6KC1,SCML2,PRMT5,FGF1,FOXG1,CAP2,SGIP1,DCTN2,SORBS1,ZNF605,CELF1,ST6GALNAC3,PHYHIPL,ZMAT1,GABRA1,GALNT15,ZMYND11,JPH4,TMEM8B,GK,TCERG1,SPIN1,GLYR1,GLS,ZNF638,GNAS,GPD2,FUT10,STMN2,DIDO1,GRIK2,NR3C1,PRDM5,SCIN,CDH20,KCNK2,KCNN2,CREG2,KIFC3,KTN1,ARHGAP12,PIK3AP1,MAT2A,MATN2,SYT9,KCTD6,LAYN,CNOT4,NOVA1,OGG1,CDK18,PDE3A,CRLS1,KANSL1,FITM2,GRAMD1C,APTX,CNTLN,PTPRE,PTPRO,CEP97,SUSD4,RBBP8,FIGN,RFX2,RGS3,SEC61A2,ZFHX4,ELP2,NEK11,ZNF671,ATAT1,RYR3,TRAPPC13,LRRTM4,ZFP2,CASC3,SHC4,HKDC1,CNKSR2,PAAF1,SLC6A7,SLC8A3,ARHGEF40,SLC14A1,SPHKAP,CPEB4,SLN,SORCS3,ANKRD36,SNRPN,TNIK,ZCCHC24,KIF21B,ZC3H13,ZC4H2,NKAIN2,SS18,NSFL1C,NECAB1,FNDC9,SYN2,DDHD2,EXOC7,CAMSAP2,ANO4,VWC2,TCF7L2,HIF3A,AP4E1,GZF1,TIMP4,NR2E1,TPM1,FNDC5,BCL2L13,RBFOX3,ZIC2,ZBTB16,PRDM2,STOX2,RNF103,PCDH15,NAV3,PCBP4,PAK5,TMEM63C,RNF170,FXR1" MicroRNA hsa-miR-616:mirSVR_highEffct hsa-miR-616:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-77 1.05E-73 8.49E-77 7.82E-76 197 812 "KCNH8,SYN3,ABHD6,ADD1,AXIN2,SLC12A5,CDC7,PWWP2A,MTUS1,KCTD16,BBOX1,ANK2,MAGEE2,API5,TMEFF1,SPTBN4,ZFYVE28,ATP2B3,ZNF583,NOL4,BACH1,MTMR2,BSN,CACNA1B,CACNB2,THSD7A,VSTM2A,CAST,LDB2,CCKBR,CDH18,LGI1,CHGB,CHRM1,CASC2,NDST3,PLAA,VAX2,QKI,ARHGEF10,SOCS5,NRSN1,RIMS2,FAM131B,DOCK4,IST1,DAPK1,AIF1L,YTHDC1,HEPH,CEP170,SNAP91,WDR20,USP3,DTNA,TOM1,DNM1L,EDNRB,FAM13A,ELAVL2,PLEKHA1,EPB41L2,EPHB1,NCALD,ANKMY1,CLVS1,CEP78,FGF1,ATP13A4,COQ5,C2orf88,SMC2,PDLIM5,FAM49B,NPTN,CELF1,STAU2,ZNF512,OGA,CAB39,ILDR2,GAD1,LRRC37A6P,KIAA1841,MYOZ2,GK,ZNF276,ZNF638,ZNF782,LILRB4,GPM6A,GPR12,STON1,GRIA2,GRIK2,NR3C1,GRM7,FAM19A2,ADAMTS6,MAEL,MIER3,SYNPO,USP51,DHX35,BRINP3,KIF5A,KLC1,SYTL4,MAT2A,MBNL1,SYT9,MDM4,MEIS1,MKLN1,MRPL42,BCO1,LAYN,MYO9A,NEUROD1,NF1,NNAT,GPR88,CLDN11,PCDH9,ENPP2,FAM218A,A2ML1,ANKRD16,PMP22,ING3,IRX1,PPP2R5E,PPP3CA,MAPK9,MAPK10,PROX1,PTPRE,FAM66C,RAP1GAP,ENOX1,ZNF493,OXR1,RASGRF2,SLC6A15,REV3L,RGS12,RIC8B,RORB,TMEM206,YY1AP1,ATP8B4,TCP11L1,CCDC112,AP1AR,SGK1,ITSN1,FERMT1,NTNG1,DZIP1,ZNF365,SLC2A5,SLC12A2,MYH15,ZC3H13,KIF1B,RBM26,NFASC,ATP10B,THSD1,SS18,NXT2,SYNE2,NUDT10,PLCB1,TAC1,MLST8,KLHL4,TRIM2,RPGRIP1L,ARHGAP9,TEK,AKTIP,TJP1,SYNPO2,STXBP4,TMPRSS5,ANKRD20A2,RFTN2,FLRT2,CLDND1,ZNF711,TCEAL7,RNF103,FIP1L1,UBE3B,FBXO36,NLRP3" MicroRNA hsa-miR-101*:mirSVR_highEffct hsa-miR-101*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.23E-77 1.26E-73 1.01E-76 9.32E-76 210 920 "NBAT1,SLC12A5,KIDINS220,BEND6,KCTD16,WDR35,ADGRF5,ALCAM,FAM135A,LRCH2,PPFIA1,ANXA7,APAF1,PRX,CASK,ARHGAP5,ASPH,CCDC181,N4BP2L1,ATP6V1G2,ARHGEF7,IL33,KALRN,SLC25A14,CAST,INA,CBFA2T2,CCPG1,MS4A7,SYNPR,ZBED5,KMT2C,PLAA,QKI,SLC4A8,SMARCAL1,ACBD5,CPS1,FEZ2,SUSD5,NCAN,SLITRK5,CTNND1,ST18,DOCK4,GAPVD1,ZFYVE16,CENPL,IST1,TOMM20,YTHDC1,CEP170,DTNA,FCF1,PHF20L1,MBNL2,KMT5B,COPS4,ING4,CALCRL,EPHA5,CEP85L,ZNF461,FABP7,ACSL4,TAOK3,GORAB,SUCO,SEC23B,ATP13A4,FLT1,TMEM107,SMC2,UFM1,KHDRBS3,CELF1,MEGF10,HBS1L,AHCYL1,ERAP1,SULT1C4,GGTA1P,GLS,MSL3,ZNF782,PSRC1,GOLGB1,LILRA1,GPR22,GRID1,RNF165,PSIP1,GUCY1B1,MAP4K5,DHX35,HSF2,DOCK7,OLFM3,KCNMA1,KIF5A,STXBP5,HECTD2,NCOA7,MAP6,MARK1,MAT2A,MATN3,MBD1,MEF2C,MEIS1,BLOC1S2,ZNF92,MXI1,MYCN,NAP1L1,NF1,VWA2,SMIM11A,NUCB2,DPY19L2P2,PENK,BEST3,ABCB1,SNX10,RETREG1,PLP1,RC3H2,SLC36A4,PPP2R5E,PRKACB,EPDR1,MAPK9,GON4L,MDGA2,PIGG,MTMR10,OCIAD1,PTPRG,FAM120C,C1orf109,QDPR,FAM184A,ZNF493,SLC6A15,REV3L,RFX3,KLHL11,YY1AP1,FBXW7,ACER3,LRRK2,ABCA11P,ATAT1,SCN2A,SGK1,SLITRK3,SEC31A,RUFY2,SLC6A11,SEPHS1,CCDC88A,SLC11A1,SLCO1A2,SPHKAP,LGI3,TET1,SMARCE1,SNRPN,UNC80,BDP1,TEX2,LMO3,POGZ,LARP4,NXT2,MPRIP,KLHL7,CAMSAP2,UNC5D,ACSL6,TCF4,ZEB1,TRIM2,PCDHGB7,SYNE1,FRYL,SIK3,TEK,C18orf54,AP4E1,SLC44A1,LRRC8A,TRIO,ZMYND8,DCBLD1,MEAF6,CCDC14,ZBTB14,CFAP52,MKRN3,FTSJ1,PLPPR5,SMARCAD1,PRDM2,LRP8,RNF103,MPPE1,KAT6A,HNRNPA3,NETO1" MicroRNA hsa-miR-199b-5p:mirSVR_highEffct hsa-miR-199b-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.24E-77 3.51E-73 2.83E-76 2.60E-75 205 883 "RALGAPA1,KCNH8,ASPHD1,ACTN2,KLHL32,CCDC85A,ADD3,CDC7,PTCHD1,OGT,LRCH2,ANK3,MAP4K3,PHF12,APBB1,ALS2,APOC1,PPFIA3,DDX3Y,ATM,FUBP1,JAZF1,OSGIN2,DDR1,KALRN,NFS1,CERS5,LRRFIP1,LGI1,LARGE1,CCPG1,CFL2,COPB2,CHN2,CHRM1,CASC2,RAB3C,CNOT8,JAM2,CLTC,FAM149A,SLC4A8,BAG4,CHD1L,PREPL,HAPLN1,RGS6,UBXN2A,RUBCN,CYBB,HDAC9,GPRASP1,GAPVD1,RASSF2,TBC1D5,ZEB2,MYEF2,KIAA0753,MAGI2,BLOC1S6,SACS,FAM107B,ABI1,E2F6,TSPAN5,OPTN,PAN3,USPL1,SRRM1,RCSD1,RACK1,FDFT1,TESK2,KIAA1109,TMEM164,SYNCRIP,IQCG,SEMA4D,SLC37A3,NBEA,TMEM107,ATP6V1H,NSG2,NSG1,SARAF,GABRA2,GAD1,NCKAP1,ZNF559,NEU3,GCNT2,SULT1C4,CSDC2,PPARGC1A,RND1,DBF4,TOX3,GLUL,GPD2,FUT10,GRIA2,GRIA4,PLCD4,PRDM5,FAM19A2,AGBL5,MSL1,IGFBP1,LRRTM3,SLC35G1,METTL21A,KCND2,KCNH2,KCNK2,KIT,LAMP2,PAXBP1,SYTL4,ARHGAP12,NCOA7,ZFYVE27,MAT2A,MBNL1,MBP,MEIS2,ERICH3,GIT1,MXI1,NF1,PDE4B,SLC10A4,PFKFB2,PIK3CD,PCDH18,TRHDE,FA2H,POU3F2,CRLS1,PRKAB2,SYTL2,PIGG,MTMR10,ZNF844,MARCH1,CEP97,SUSD4,FIGN,RGS10,SEC61A2,ROBO2,RORB,ELP2,MRAP2,NEK11,KCNIP1,CLIP1,SATB1,LRRTM4,ZFP2,ASRGL1,KIF21A,ITSN1,NTNG1,NLGN1,SLC1A6,BTBD7,SORCS3,SMARCE1,RCOR3,UNC80,WDTC1,SOX2,ENKUR,KIF1B,EPB41L3,LARP4,NXT2,ZSCAN29,ADHFE1,FGD4,CAMSAP2,ANO4,ZEB1,DNAH7,SIRT1,CRB1,ERCC6L2,TMPO,RUSC1,TMPRSS5,TSC1,TST,HIRA,XRCC4,PCDH20,ZNF19,PCBP1-AS1,MFF,LRP8,STOX2,TMEM163,WNK3,FAM13C,PHTF2,CASC15" MicroRNA hsa-miR-214:mirSVR_highEffct hsa-miR-214:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.67E-77 3.75E-73 3.02E-76 2.78E-75 207 900 "KCNH8,ACLY,SYS1,KLHL32,BRAP,SORCS1,PWWP2A,ADRA1D,AP2A2,INTS2,C1QTNF3,LRRC7,FAM135A,OGT,ANK3,ALS2,ASTN1,ATM,RGS9,SCAPER,IL33,DDR1,CACNB2,LURAP1,CALB2,THSD7A,PTBP2,LRRFIP1,DLGAP1,SRSF11,RAB33A,PLAA,PPT2,QKI,FAM149A,COL4A5,TBPL1,MFSD4A,ENTPD4,CS,SEC24C,ATRNL1,SOCS5,PHACTR3,CMTM5,PUM1,DCAF4,EDRF1,HDAC9,RIPOR2,DGKG,GIT2,JAKMIP2,ZEB2,MYEF2,C2CD2L,SV2B,SRGAP3,DMPK,ABCC5,SGK2,SEMA3D,YAF2,PHF20L1,ING4,DCTN4,RCSD1,F8,CLVS1,WAC,TAOK3,FGF1,FGF14,FHL1,IP6K2,SYNCRIP,IQCG,NELFCD,TMEM107,FAM49B,NPTN,ATP2C1,ARPP21,ZNF274,NCKAP1,SULT1C4,GPR162,SESN1,AHDC1,USP19,PCDH17,DHRS4,ZNF638,KCNMB4,GNAL,ZNF782,TDRKH,PCLO,GRIK2,GRM7,BTN2A1,FAM19A2,RNF165,PTPN5,RNFT2,SLC2A6,MAEL,MAN1B1,SHISA6,MSL1,IGF1,ZIC5,IL11RA,KCNB1,KCNN1,KIF5A,KLRC2,MAP6,MITF,MT3,NF1,NINJ2,VWA2,HCN1,NUCB2,IGSF11,LOC100128398,PAH,PBX1,PDE4A,PDGFRA,GPR85,ABCB1,NOMO2,FTO,SEPT4,PPM1B,HYDIN,RELN,SIDT1,QRICH1,BDNF-AS,PTHLH,PTH1R,TMEM260,PPP2R3C,PID1,TMEM255A,OXR1,GTDC1,EXD2,SPIN3,ACER3,STK32B,SALL1,ATXN7,SCN3A,TRA2B,NTNG1,CHD9,CNKSR2,ST3GAL3,CLSTN1,ABLIM3,ZNF365,DHX30,KDM4D,SLC8A1,SLC11A1,CPEB4,IFT122,ANKRD36,RBM34,MYT1L,DBNDD2,NPAS3,RGL1,NSFL1C,MMS19,DMXL2,TPCN2,DOCK9,AHCYL2,HIF3A,SIK3,TEK,SIRT1,TIAM1,TPM3,FAM155A,UCHL1,UGT8,SLAIN1,MEAF6,P2RY12,PCDH20,POLR3H,ANKS1B,SPIRE1,PRDM2,PRDM10,PPP1R3F,PLSCR4,SMIM8,ZNF248,SLC4A10,GAN" MicroRNA hsa-miR-4279:mirSVR_highEffct hsa-miR-4279:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.79E-77 4.37E-73 3.52E-76 3.24E-75 214 960 "FAM43B,ARID1A,ADCY2,SLC12A5,PWWP2A,CC2D2A,ARHGAP20,PPFIA1,UPRT,DDO,SEMA4G,PPP4R4,CASK,DACT3,NCOA1,SLC2A11,ATP6V1G2,RGS9,MMD2,CACNA1E,CACNB4,ARHGEF25,ZNF501,CCNH,CCNT1,P2RX6,ZMYM4,LARGE1,SYNPR,CLCN3,SLC24A2,NMT2,SRP14-AS1,IGLON5,BTF3L4,IGDCC3,CHD1L,HAPLN1,CSF2RA,CSF3R,FEZ1,ARHGEF10,PLCXD3,PNPLA8,RUBCN,CCDC144A,GAPVD1,TOX,ZFYVE16,DGKB,DGKG,DAPK1,DBI,ARMCX4,DNAJC6,ZEB2,SMG7,SV2B,DMD,DNM1,DPYSL2,DYRK1A,E2F5,AASDH,MBNL2,RCAN2,NCALD,CDKL3,ETV1,EXTL2,EZH1,F8,CLVS1,MED12L,FGF1,PRKAG2,MEX3B,SLC37A3,NOP56,NELFCD,SPECC1,ZNF512,MEGF11,ARPP21,C15orf41,DISC1,IGSF5,GPR162,PCDH17,ZNF276,GLI2,GPER1,STMN2,GRIA2,PLCD4,SERP2,LINC00839,COQ10A,HLF,SYNPO,MSL1,C5orf24,PLD5,ITGA7,KCND1,KCNK1,KCNMA1,KCNN3,KIF5C,STXBP5,TTYH2,LIMS1,ZFYVE27,MBNL1,LRP1B,AFF1,AFDN,MMP16,MSR1,MTR,MYO7A,ZNF862,NF1,OTOGL,CNOT4,DNHD1,P2RX7,GLIPR1L2,SNTG1,PAK3,GNG2,A2ML1,SH3KBP1,C19orf57,MED1,PPM1B,PPP2R2B,GRAMD1C,WBP1L,LAMA1,PIGG,MTMR10,PTK2,TMEM260,ZSCAN2,RAD51D,ENOX1,OXR1,RFX4,GSTCD,ROBO2,SPIN3,TCP11L1,ATXN7,SCN3A,SCN8A,SMPD3,SELL,ITSN1,SH3GL2,FNDC3A,ANKRD6,FAM81A,SLC6A11,BTBD7,CPEB4,SMARCE1,RCOR3,IFT122,SOX2,DBNDD2,ZBTB43,NPAS3,C11orf87,CLASP2,ADAMTS17,SYN2,ASTN2,UNC5D,ANO4,TCEA1,ZFP90,SZT2,WDR7,SYNE1,DOCK9,SLC19A3,KHDC1,SLC44A1,FAM124A,TNR,WBP2,ZNF346,PRMT8,AMACR,UBE3A,USP1,ZIC1,ZIC3,ZNF74,LYPD6,ZSCAN26,UPF3A,CA10,PRDM2,DNALI1,STMN4,RNF103,MVB12B,DOCK8,KAT6A,CBLN2,SLC4A10,LAS1L" MicroRNA hsa-miR-206:TargetScan hsa-miR-206 TargetScan 8.17E-77 4.59E-73 3.69E-76 3.40E-75 173 632 "RALGAPA1,NDRG3,ADAR,RNF157,RNF150,GPR158,HECW2,HACE1,OSBPL8,MAP4K3,DGKZ,MIER1,CASK,ARNTL,ASPH,NCOA1,DDX3Y,ATP6V0A1,BCL2L2,BCL7A,FGF17,NRP2,BMPR1B,FUBP1,BSN,MMD2,CA8,CA12,CALM1,KALRN,CDC42,CDR1,CLCN3,NMT2,CLTC,QKI,CNN3,BAG4,CLOCK,CREM,CREB5,AKAP12,RNF14,CSF1,RIMS4,PLXNA4,KIAA0040,CTNND2,HDAC4,MATR3,DGKG,AIF1L,DNAL1,PLEKHM1,MYEF2,ELMO1,HP1BP3,MAGI2,G3BP2,RABGAP1L,FAM107B,DLG2,DLG4,DMPK,CDON,DPH1,GNE,ECM2,E2F5,EDN1,PHC2,HIPK3,HEYL,KLHL5,CELSR3,ABI2,PLEKHA1,BSCL2,EMX2,EPB41L1,EPB41L2,RCAN2,RABEPK,RTN3,AMOTL2,SEC23B,NBEA,CPLX2,GBX2,ARFIP1,PCDH17,GLYR1,GLS,KDM2B,GPD2,NUDT21,EML4,RFFL,RNF165,IL1RAPL1,KAT7,GUCY1A2,BACH2,HMGCR,HNRNPK,IGF1,IL6ST,KCND3,KIF2A,KTN1,MEIS1,PPM1L,MOG,GIT1,DBNL,MYO9A,NRCAM,HCN1,GPR137C,PAK3,PAX6,PIRT,GPR85,PFKFB2,CDK14,GDAP1L1,PIK3C2A,EPB41L4B,MED1,PRKACB,MAPK3,CNNM2,PTPRD,PTPRG,PEX2,MSANTD2,GTDC1,RFX3,RIT2,FBXW7,KCNIP3,ATXN2,MRAS,FAM102A,PPP1R9A,MYO18A,FNDC3A,PEX26,EPC1,MAPKBP1,RBM26,NPAS3,LARP4,NXT2,DIP2A,FAM168A,NECAB1,FGD4,NSD1,GPRIN3,DICER1,ARL10,ASXL3,LRRC8A,KAT6B,FAM155A,AMOT,RICTOR,KAT6A,HNRNPA3,ADAMTSL3,NETO1,GAN" MicroRNA hsa-miR-1-3p:TargetScan hsa-miR-1-3p TargetScan 8.17E-77 4.59E-73 3.69E-76 3.40E-75 173 632 "RALGAPA1,NDRG3,ADAR,RNF157,RNF150,GPR158,HECW2,HACE1,OSBPL8,MAP4K3,DGKZ,MIER1,CASK,ARNTL,ASPH,NCOA1,DDX3Y,ATP6V0A1,BCL2L2,BCL7A,FGF17,NRP2,BMPR1B,FUBP1,BSN,MMD2,CA8,CA12,CALM1,KALRN,CDC42,CDR1,CLCN3,NMT2,CLTC,QKI,CNN3,BAG4,CLOCK,CREM,CREB5,AKAP12,RNF14,CSF1,RIMS4,PLXNA4,KIAA0040,CTNND2,HDAC4,MATR3,DGKG,AIF1L,DNAL1,PLEKHM1,MYEF2,ELMO1,HP1BP3,MAGI2,G3BP2,RABGAP1L,FAM107B,DLG2,DLG4,DMPK,CDON,DPH1,GNE,ECM2,E2F5,EDN1,PHC2,HIPK3,HEYL,KLHL5,CELSR3,ABI2,PLEKHA1,BSCL2,EMX2,EPB41L1,EPB41L2,RCAN2,RABEPK,RTN3,AMOTL2,SEC23B,NBEA,CPLX2,GBX2,ARFIP1,PCDH17,GLYR1,GLS,KDM2B,GPD2,NUDT21,EML4,RFFL,RNF165,IL1RAPL1,KAT7,GUCY1A2,BACH2,HMGCR,HNRNPK,IGF1,IL6ST,KCND3,KIF2A,KTN1,MEIS1,PPM1L,MOG,GIT1,DBNL,MYO9A,NRCAM,HCN1,GPR137C,PAK3,PAX6,PIRT,GPR85,PFKFB2,CDK14,GDAP1L1,PIK3C2A,EPB41L4B,MED1,PRKACB,MAPK3,CNNM2,PTPRD,PTPRG,PEX2,MSANTD2,GTDC1,RFX3,RIT2,FBXW7,KCNIP3,ATXN2,MRAS,FAM102A,PPP1R9A,MYO18A,FNDC3A,PEX26,EPC1,MAPKBP1,RBM26,NPAS3,LARP4,NXT2,DIP2A,FAM168A,NECAB1,FGD4,NSD1,GPRIN3,DICER1,ARL10,ASXL3,LRRC8A,KAT6B,FAM155A,AMOT,RICTOR,KAT6A,HNRNPA3,ADAMTSL3,NETO1,GAN" MicroRNA hsa-miR-20b*:mirSVR_highEffct hsa-miR-20b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-76 1.01E-72 8.09E-76 7.45E-75 202 863 "CSMD3,PTCHD1,PCDH19,HACE1,OGT,CDC42BPA,ANK3,APC,UPRT,ALS2,APOC1,API5,APP,SHTN1,MIER1,IGDCC4,ARNTL,ASPH,ZBTB10,ATP2A2,ATP2B3,ADGRB3,DST,ARHGEF7,MTMR2,CACNA1D,CACNB2,CALB1,CALB2,CAST,LDB2,KRIT1,CHN2,SYNPR,CNOT8,CLTA,FBXO7,HECTD1,SLC4A7,SLC4A8,AHCTF1,CHD1L,CREM,AKAP12,RNF14,ATRNL1,ERC2,NRSN1,USP6NL,KCTD8,DNAJC6,COPS7A,ARNT2,DMTF1,ARRDC4,SEZ6L2,TSPAN5,ATL1,PHC2,SGK2,FSD1L,YAF2,FAM13A,PHF20L1,SUGP2,KMT5B,SORBS3,RGS17,C8orf37,CALCRL,CEP85L,ETV1,F3,F8,ZNF461,TMEM132C,CEP78,KIAA1109,NPTN,PHYHIPL,GABRA1,GABRA3,BRPF3,ZMYND11,ARPP21,NCKAP1,C15orf41,SULT1C4,PCDH17,GLRB,GLS,PCDH11X,ZNF638,GPD2,GPM6A,PCLO,DIDO1,GRIA4,GRID1,GRM5,GSTM5,MAP4K5,MAEL,HPS5,HMGB1,HMGCR,TCEAL6,ZNF181,ZNF678,ITGAV,KCNA2,KCNN2,CREG2,LMO2,VWA5A,PIK3AP1,MAP2,MAP4,SYT9,MDM4,LRP1B,MIA2,ADAM22,ZNF92,TCEAL5,VWA2,SLC11A2,PBX1,PCSK5,PDE4B,PDE4D,GNG2,CYTL1,NALCN,XRN1,FAM216A,PLP1,PRRX1,NXPH1,MINDY2,PPM1B,LRRN3,PPP3CA,RANBP3L,EPDR1,MAPK10,MDGA2,CNTLN,PTAFR,PTK2,EML5,PTPRZ1,ZNF615,ZNF493,ARID4A,GAL3ST4,RNF220,RNASE1,RPRD1A,ABCA11P,SCN3A,NTNG1,RAB3GAP1,RCOR3,SNCA,MBD5,SNRPN,TNIK,NPAS3,SEPT8,ADHFE1,NUDT10,COBL,ANO4,TCF4,ZFP90,CRB1,ITGB3BP,TGFBR3,TJP1,ACTR6,TMPO,PPIL6,TMEFF2,SGK3,CLDND1,ZNF711,FSTL5,PCDH15,TMEM163,LINC00632,FAM47E,FAM13C,AMN1,HNRNPA3,FBXO36,CASC15,ACTR3B,ADAMTSL3,NHSL1,FRMD6,NETO1" MicroRNA "TGCACTT,MIR-519C:MSigDB" "TGCACTT,MIR-519C:MSigDB" MSigDB 2.03E-76 1.14E-72 9.12E-76 8.40E-75 142 421 "SLC24A4,OGT,LRCH2,RASL11B,DDX3Y,BCL2L2,NRP2,NIPA1,MYRF,MAP7,USP6,CFL2,SOCS6,ZFYVE9,QKI,BTF3L4,SLC4A7,AHCTF1,CREB5,GDA,LRIG1,PPP6R2,ARHGAP24,KIAA0513,MAML1,FBXL5,SACS,SRGAP3,WDR20,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,TESK2,FOXG1,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,RAPGEF4,GRM7,PTPRT,SOX21,HAS2,HPS5,KLF12,IGF1,KCND2,KCNJ10,KCNN2,KCNQ2,KIF5A,LAMP2,CAMK2N2,ARHGAP12,MAP4,MBNL1,MYT1,NBL1,NF1,NFIA,NFIX,NHLH1,CNOT4,PDGFRA,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,PTHLH,RAB5B,CEP97,RAD52,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,BTBD7,SOX5,TSPYL2,SMOC1,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,ZFP91,HEY2,R3HDM1,UBE3A,VLDLR,NSD2,RICTOR,PCDH20,USP32P2,FSTL5,CA10,MAP3K12,EMSY,WNK3,GOPC,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA "TGCACTT,MIR-519B:MSigDB" "TGCACTT,MIR-519B:MSigDB" MSigDB 2.03E-76 1.14E-72 9.12E-76 8.40E-75 142 421 "SLC24A4,OGT,LRCH2,RASL11B,DDX3Y,BCL2L2,NRP2,NIPA1,MYRF,MAP7,USP6,CFL2,SOCS6,ZFYVE9,QKI,BTF3L4,SLC4A7,AHCTF1,CREB5,GDA,LRIG1,PPP6R2,ARHGAP24,KIAA0513,MAML1,FBXL5,SACS,SRGAP3,WDR20,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,TESK2,FOXG1,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,RAPGEF4,GRM7,PTPRT,SOX21,HAS2,HPS5,KLF12,IGF1,KCND2,KCNJ10,KCNN2,KCNQ2,KIF5A,LAMP2,CAMK2N2,ARHGAP12,MAP4,MBNL1,MYT1,NBL1,NF1,NFIA,NFIX,NHLH1,CNOT4,PDGFRA,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,PTHLH,RAB5B,CEP97,RAD52,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,BTBD7,SOX5,TSPYL2,SMOC1,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,ZFP91,HEY2,R3HDM1,UBE3A,VLDLR,NSD2,RICTOR,PCDH20,USP32P2,FSTL5,CA10,MAP3K12,EMSY,WNK3,GOPC,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA "TGCACTT,MIR-519A:MSigDB" "TGCACTT,MIR-519A:MSigDB" MSigDB 2.03E-76 1.14E-72 9.12E-76 8.40E-75 142 421 "SLC24A4,OGT,LRCH2,RASL11B,DDX3Y,BCL2L2,NRP2,NIPA1,MYRF,MAP7,USP6,CFL2,SOCS6,ZFYVE9,QKI,BTF3L4,SLC4A7,AHCTF1,CREB5,GDA,LRIG1,PPP6R2,ARHGAP24,KIAA0513,MAML1,FBXL5,SACS,SRGAP3,WDR20,USP3,DNM2,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM13A,KMT5B,EIF4G2,EMX2,ERBB4,ACSL4,TAOK3,TESK2,FOXG1,FOXF2,ANKFY1,NBEA,ATP2C1,TNRC6A,RAPGEF4,GRM7,PTPRT,SOX21,HAS2,HPS5,KLF12,IGF1,KCND2,KCNJ10,KCNN2,KCNQ2,KIF5A,LAMP2,CAMK2N2,ARHGAP12,MAP4,MBNL1,MYT1,NBL1,NF1,NFIA,NFIX,NHLH1,CNOT4,PDGFRA,PIK3R1,EPB41L4B,PPP3CA,PKIA,MAPK4,PSD,SNRK,PTHLH,RAB5B,CEP97,RAD52,ATG16L1,ARID4A,RBBP6,RFX3,ZFHX4,RORB,RTN1,RYR3,PUF60,CHD9,SLITRK3,SYBU,SLC1A2,CCDC88A,SHANK2,BTBD7,SOX5,TSPYL2,SMOC1,LARP4,ERBIN,DIP2A,PLCB1,SYN2,SYT1,ANKRD12,FBXW11,TBL1X,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,THRA,ZFP91,HEY2,R3HDM1,UBE3A,VLDLR,NSD2,RICTOR,PCDH20,USP32P2,FSTL5,CA10,MAP3K12,EMSY,WNK3,GOPC,PHTF2,FRMD6,NETO2,ST8SIA2" MicroRNA hsa-miR-128:PITA hsa-miR-128:PITA_TOP PITA 2.16E-76 1.21E-72 9.70E-76 8.94E-75 155 507 "RALGAPA1,SDE2,ADCY2,ADCY6,SPOP,PITPNM2,APBA2,GPAM,TMEFF1,PDE8B,RNF182,DPY19L3,DOCK11,CANX,COPB2,FOXN3,SOCS6,DLGAP3,KIAA1549L,HECTD1,NIPBL,CNR1,ARMC8,CABP1,ZNF385A,RGS6,NCAN,SOCS5,ERC2,CTNND2,GAPVD1,SPATA2,SV2A,DLG2,DMTF1,DRP2,ABCC5,EGR3,TMEM132E,EML1,RCAN2,DMTN,SRRM1,EZH1,DLC1,ATP8A1,PRKAG2,UBE2E3,AGAP3,AFF2,SYT3,DOT1L,MEGF11,GAD2,GHR,PPARGC1A,RUNDC3A,GK,TPPP,GRIN2D,PTPRT,PTPN5,TMEM25,KAT7,MFSD2A,MAP4K5,WIF1,SMAP1,IGF1,IBA57,INSM1,KCNA1,KCNK2,ARHGAP12,MPP2,MXI1,NCAM1,ZC3H12B,NEUROD1,NF1,NPTX1,NTRK3,KSR2,TBC1D25,OPA1,ZNF827,KCNK10,PDE3A,PDE1B,PIK3R1,HMGCLL1,CDIP1,MED1,RASGEF1B,DIRAS2,RELN,WBP1L,PTPRB,FAM120C,FAM184A,RDX,RET,KLHDC8A,RORB,SYNDIG1,AMER2,SEMA6D,CASC3,FAM102A,PPP1R9A,SH3GL3,PPM1E,NTNG1,FNDC3A,CCDC92,CCDC88A,TRIM67,RCOR3,RIMS1,FAM126B,SP2,SP4,TEX2,SRPK2,POGZ,SS18,MAPK8IP3,ELOVL4,VAMP1,PLCB1,SYT1,TAL1,PDLIM2,TCF4,WASHC4,CLASP1,WDR7,FRYL,SIRT1,CBX5,DDHD1,TUB,FAM155A,CCDC136,TMEM237,DPYSL5,WNK1,CA10,NAV3,KCNAB1,MVB12B,RTN4,KAT6A,VANGL2,NETO2" MicroRNA "ACTGTGA,MIR-27A:MSigDB" "ACTGTGA,MIR-27A:MSigDB" MSigDB 2.23E-76 1.25E-72 9.99E-76 9.20E-75 146 447 "SLITRK1,ADCY6,PLEKHH1,AK2,SEMA6A,PITPNM2,ANK1,ANK2,APAF1,APBA2,GPAM,CHRD,NCOA1,STX16,ATP2B1,DPY19L3,NRP2,CA12,CACNB2,DIRAS1,CAPN3,C1orf52,CDC42,FOXN3,SOCS6,CLCN3,NRXN1,QKI,ARMC8,CABP1,IFFO1,ZNF385A,SLC35F1,HAPLN1,CSF1,RGS6,EDRF1,ECE2,LONRF1,RIMS3,SPATA2,ELMO1,POM121,SV2A,ARRDC4,E2F6,EDNRA,FAM13A,EGFR,MBNL2,LPAR6,EN2,EPB41,EPB41L1,RCAN2,DNAJC27,EYA1,SUCO,RGPD5,PDLIM5,ST6GALNAC3,DOT1L,BRSK1,NEURL4,GABRB3,CAB39,BRPF3,NEK6,PCDH17,RUNDC3A,CIT,PTPRT,TMEM25,MFSD2A,FAM222A,ZHX1,SOWAHA,KCNA6,KCNK2,LIFR,ARHGAP12,NCOA7,AQP11,MATN3,MDFI,MEIS2,MSI1,MYT1,NFE2L2,NOVA1,NPTX2,ZNF827,CDK18,PDE3A,PDGFRA,PDPK1,CDIP1,POU3F2,PPARA,PKIA,RELN,MTMR10,NKAIN1,FAM184A,ZFHX4,FBXW7,RXRA,SEMA6D,CASC3,PPM1E,CPEB3,SLC1A2,URGCP,SLC6A1,CPEB4,SNAP25,TMCC1,WDTC1,ZCCHC24,SOX11,KDM3A,NFASC,TROVE2,COLGALT2,NXT2,MAPK8IP3,SEPT3,SYT1,CAMTA1,UNC5D,KLHL4,SATB2,RPGRIP1L,WASHC4,TSC1,FLRT2,PLEKHH2,MICU3,PLPPR5,CA10,EVI5,NAV2,JMJD1C,VANGL2,ADAMTS10,NETO1" MicroRNA "ACTGTGA,MIR-27B:MSigDB" "ACTGTGA,MIR-27B:MSigDB" MSigDB 2.23E-76 1.25E-72 9.99E-76 9.20E-75 146 447 "SLITRK1,ADCY6,PLEKHH1,AK2,SEMA6A,PITPNM2,ANK1,ANK2,APAF1,APBA2,GPAM,CHRD,NCOA1,STX16,ATP2B1,DPY19L3,NRP2,CA12,CACNB2,DIRAS1,CAPN3,C1orf52,CDC42,FOXN3,SOCS6,CLCN3,NRXN1,QKI,ARMC8,CABP1,IFFO1,ZNF385A,SLC35F1,HAPLN1,CSF1,RGS6,EDRF1,ECE2,LONRF1,RIMS3,SPATA2,ELMO1,POM121,SV2A,ARRDC4,E2F6,EDNRA,FAM13A,EGFR,MBNL2,LPAR6,EN2,EPB41,EPB41L1,RCAN2,DNAJC27,EYA1,SUCO,RGPD5,PDLIM5,ST6GALNAC3,DOT1L,BRSK1,NEURL4,GABRB3,CAB39,BRPF3,NEK6,PCDH17,RUNDC3A,CIT,PTPRT,TMEM25,MFSD2A,FAM222A,ZHX1,SOWAHA,KCNA6,KCNK2,LIFR,ARHGAP12,NCOA7,AQP11,MATN3,MDFI,MEIS2,MSI1,MYT1,NFE2L2,NOVA1,NPTX2,ZNF827,CDK18,PDE3A,PDGFRA,PDPK1,CDIP1,POU3F2,PPARA,PKIA,RELN,MTMR10,NKAIN1,FAM184A,ZFHX4,FBXW7,RXRA,SEMA6D,CASC3,PPM1E,CPEB3,SLC1A2,URGCP,SLC6A1,CPEB4,SNAP25,TMCC1,WDTC1,ZCCHC24,SOX11,KDM3A,NFASC,TROVE2,COLGALT2,NXT2,MAPK8IP3,SEPT3,SYT1,CAMTA1,UNC5D,KLHL4,SATB2,RPGRIP1L,WASHC4,TSC1,FLRT2,PLEKHH2,MICU3,PLPPR5,CA10,EVI5,NAV2,JMJD1C,VANGL2,ADAMTS10,NETO1" MicroRNA hsa-miR-4257:mirSVR_highEffct hsa-miR-4257:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-76 1.36E-72 1.09E-75 1.00E-74 194 799 "CLK4,ADD3,KIAA1211,AK2,UNC79,MYH7B,MIER1,ASCL1,SYNJ2,CACNB2,LURAP1,KALRN,BRSK2,CCKBR,TMEM257,CDC42,CDH2,SRSF11,CHN2,CNOT8,EPS15L1,IGFBP7-AS1,PPT2,DNAJB5,QKI,IQCK,AKAP5,MFSD4A,AKAP12,RNF14,CLIP3,CSNK1E,SUSD5,SOCS5,PDE4DIP,PHACTR3,CST3,DZIP3,CTH,CFAP61,MED24,ZC3H11A,PLPPR4,DLG4,DMD,DYNC1I1,DPH1,ABCC9,USH1C,ATL1,ANKRD46,FAM13A,PHF20L1,EGFR,KMT5B,TENM1,SEZ6,SRRM1,FDFT1,ZNF589,C1orf61,NELFCD,STAMBP,TPK1,CELF1,ADGRA1,ZNF512,FYN,ZMAT1,GALNT15,ILDR2,NEK6,ACSS1,GATM,PPARGC1A,GK,TNRC6A,LUZP2,GPM6A,FUT10,RAPGEF4,GRIA1,GRIA4,GRM7,ZNF496,GYG1,AGBL5,OPALIN,HTR5A,IDH3A,IDH3B,PLD5,IL6ST,IL11RA,IL12A,ITGAV,SLC35G1,METTL21A,KCNK3,CREG2,L1CAM,LAMP2,SMAD1,MAOB,MARK1,MDM4,SRSF12,COL28A1,STK32C,LAYN,HNRNPM,NAP1L1,NEK1,NOVA1,DNHD1,PCSK2,CYTL1,GDAP1L1,ZNF655,PPP3CB,PRKACB,PKIA,HYDIN,MASP1,PIGG,CNTLN,PTPRG,RAB5B,SLC25A48,VEPH1,TRIM68,RIT2,ZFHX4,RAVER2,GSTCD,MRAP2,RPE,EPHA10,ABCA11P,ATAT1,ATXN7,ZFP2,DOCK10,NUBPL,PAAF1,ABLIM3,URGCP,PPP4R3A,RUFY2,SLC6A7,RAB3GAP1,DMRTC1,ANKRD36,RBM34,DOP1A,WDTC1,CLASP2,CLSTN2,SST,DIP2A,PRRC2C,PLCB1,SLC37A2,FBXW11,SMG6,SATB2,TRIM2,SZT2,HIF3A,HEY1,TJP1,FAM124A,CSMD1,TPM3,TRH,TRIO,FNDC5,FAM155A,GUSBP1,ZFP37,TRIM9,GPR158-AS1,TCEAL7,ZNF142,SYNC,PRDM2,LMAN2L,TMEM178A,CIAPIN1,MVB12B,MRPL47,UBE3B,CASC15,ZNF248" MicroRNA hsa-miR-663:mirSVR_lowEffct hsa-miR-663:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.91E-76 1.64E-72 1.30E-75 1.20E-74 196 816 "DPF1,ASIC2,ACHE,CLK4,SLITRK1,ADORA1,OLMALINC,AP2A2,PLA2G6,LTBP4,MRTFA,AMPD2,PHF12,CNIH2,DGKD,NT5C3B,PPFIA3,APP,CDC14B,MIER1,CDK10,PRX,MADD,ARRB2,LINC00173,ADAM15,ADGRB2,KSR1,CDK5R1,CACNA1E,PTBP2,NGB,RHBDL1,SLC16A4,ARHGEF1,ENTPD2,CDC25B,KCNAB3,DLGAP1,CCPG1,CACNA2D2,ASIC3,TAOK2,EPS15L1,PPT2,IQCK,HS3ST5,ZNF385A,SLC32A1,NCOR2,CSF1,MICAL2,PITPNM3,KIAA0040,CFAP61,DBN1,DLG4,DNM1,NYAP1,TNK2,MFSD10,MTSS1L,ANKRD13B,RABEPK,RASL12,EXTL1,DLC1,FCGRT,FDFT1,OLFM1,FGF11,AGAP2,FLT1,ERGIC3,KBTBD12,ADGRA1,DOT1L,GHDC,INPP5K,ALDH1L1,TUBA8,GLYR1,PCSK1N,GPD1,ATF7,GPER1,GRIN2C,GRIN2D,GRM1,KIF3A,TMEM25,PACSIN2,HRH3,ATXN2L,HPSE2,LRRC75A,IRF8,FAM95B1,MYLK2,C2CD4C,KCNJ11,GATD1,KIFC3,LINC00634,LRRC4B,SYT9,XRRA1,RTL5,RCOR2,NUCB1,SETD4,PALM,PDGFRA,GDAP1L1,NLE1,FXYD1,MTRF1L,CDIP1,PILRA,PPP5C,VSTM2L,PRKCG,RAB3A,SUSD4,RASGRF2,RFX2,RNF220,MYH14,SNX22,ATAT1,CLIP1,AMER2,TRIM46,ITSN1,SH3GL3,ST6GAL1,BCAN,CLSTN1,ABLIM3,FAM81A,SLC1A7,SLC6A9,SNCB,MAPKBP1,SOX1,KIF21B,SOX10,SP2,IQSEC2,MCF2L2,RAP1GAP2,C11orf87,NCDN,STX1A,ZFR2,C3orf70,SYN2,TBX15,SATB2,PCDHAC2,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CYB561A3,SPX,CDH22,FBXL16,GALNT17,TIAM1,RELL2,LRRC8A,KCTD2,RASD2,IL34,WBP2,ELP5,AMACR,TTTY15,TOM1L2,VLDLR,LMF1,PORCN,KCNK12,ZIC2,ZNF19,ATP6V0E2,ZNF70,SPHK2,DPYSL5,WNK2,JPH3" MicroRNA hsa-miR-299-5p:mirSVR_highEffct hsa-miR-299-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.13E-76 1.76E-72 1.40E-75 1.29E-74 173 637 "ABR,CLK4,NCKAP5,CSMD3,MTUS1,KLHL13,OSBPL8,ALCAM,LRCH2,PHF12,ANXA7,GPAM,ALS2,CASK,ZBTB10,CCAR2,EIF4G3,STX16,N4BP2L1,BACH1,RGS9,CDK5R1,DST,SYNJ1,JAZF1,CD86,LRBA,CDH10,NRXN1,SULT4A1,CNTN1,SLC4A7,CHD1L,CREM,TRIM69,SOCS5,ERC2,NRSN1,DOCK4,HDAC9,LONRF1,KIAA0586,PABPC5,SIRPA,ARMCX2,C8orf34,BLOC1S6,DDX46,G3BP2,DLG2,CPEB2,PDCD6IP,FAM78B,ABCC5,FAM135B,EDNRB,HIPK3,FSD1L,FAM13A,PHF20L1,ELN,CALCRL,DCTN4,EN2,ENPP6,WAC,GORAB,FGF14,CAMSAP1,FOXG1,UFM1,STAU2,TBR1,ABLIM2,OGA,PHYHIPL,MEGF10,CAB39,IQGAP2,AHDC1,GFRA2,GGT7,TCERG1,GLS,TOX3,MSL3,RAB40B,GPD2,GPR34,CECR2,GRIA4,GRM7,FAM19A2,WIF1,HNMT,C9orf129,DHX35,ZIC5,RBPJ,USP54,LRRTM3,LRRTM1,GATD1,MAT2A,KITLG,NF1,NPR2,CLEC9A,SLC11A2,HCN1,SNTG1,PCDH8,PDE3B,ENPP2,PFKFB2,NLGN3,KCTD15,PRIMPOL,LRP12,SLC36A4,VPS13C,PTPRD,PTPRN2,RASGRF2,ZMAT4,GTDC1,RFX3,RFX5,ZFHX4,ROBO1,PCMTD2,CCDC112,SCN2A,FNIP1,SGK1,MYO18A,CHD9,FHOD3,CTXN2,SIRT2,CCDC88A,SLC14A1,ELMO2,MBD5,UNC80,PDZD2,TEX2,BEX1,KIF1B,CDK19,POGZ,FGD4,PLCB1,TACR1,DDHD2,DNMBP,CAMSAP2,FBXW11,PUM2,TEX15,AKTIP,HEY1,TPD52,SF1,TCEAL7,FSTL5,EML6,SLC30A4,EMSY,NAV3,KCNAB1,MPPE1,TRAM2-AS1" MicroRNA hsa-miR-3157:mirSVR_highEffct hsa-miR-3157:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.44E-76 1.93E-72 1.54E-75 1.42E-74 205 891 "ACADM,NBAT1,ERMN,RNF150,RTL9,TBC1D14,KIAA1324,ALCAM,ANK2,PHF12,ALS2,PHYHD1,PDXK,TMEM263,CHRD,RASL11B,N4BP2L1,ADAM23,CFLAR,MTMR2,OSGIN2,PTBP2,VXN,VSTM2A,CCK,CNOT8,LHX2,TPP1,STOML1,CNR1,AKAP6,SLC4A8,CP,RBM39,AKAP12,SEC24C,MICAL2,VAC14-AS1,GREB1,CTNND1,DOCK4,FGFR1OP2,KATNAL2,FRMPD4,ZFYVE16,INTS1,DGKB,DBI,GIT2,ARMCX4,C8orf34,HP1BP3,FBXL5,DLG2,DLG4,EXOG,DNM1,GNE,EDN3,FCF1,EGFR,EIF4G1,EML1,STARD3NL,EPB41L1,KCNMB2,CDHR1,RTN3,NSRP1,WAC,FABP7,ZIC4,FDFT1,PPP1R1B,OLFM1,FGF12,CAP2,NELFCD,TMEM107,SPECC1,USP16,TRIM16,MSANTD4,FAM120B,RAPGEF6,ARPP21,DISC1,IGSF5,ADAM28,GHR,HPGDS,TOX3,ZNF638,STMN2,GRIK2,GRM7,GRM8,KIF3A,SOX21,TOX2,ZHX1,MIER3,HNRNPK,DOCK7,SCIN,KCNQ3,CYP27C1,SYTL4,NCOA7,MBD1,MEIS2,POC1B,MSI1,MTTP,MXI1,LYRM9,NASP,NPY,NOVA1,DNHD1,NRDC,HCN1,OGDH,ZDHHC22,PCSK2,CDK18,PDE1C,PDE3B,PDE4D,PDGFRA,TMEM38A,HMGCLL1,PDZRN4,RC3H2,PPM1B,TATDN3,PPP3CA,DCHS2,RELN,SNRK,MDGA2,PIGG,C1orf109,PID1,PLEKHB2,KHDRBS2,ZYG11B,RIC8B,RNASEL,ELP2,SPIN3,ADAL,ATAT1,SCN8A,TRIM46,SELL,SUPT20H,SCAF8,KIF21A,ITSN1,SH3GL3,SHC4,SLC1A3,WDR47,SLC8A3,ATF7IP,CPEB4,ZFP1,CDK5RAP2,SNAP25,SNRPN,KDM4C,CDK19,ATP10B,LARP4,NKAIN2,FGD4,NUDT10,SYT4,ROBO3,AGTPBP1,PCDHB4,FRYL,TEX15,TEK,ZFPM2,ITGB3BP,HHIP,R3HDM1,TPM1,SYNPO2,PRMT8,TTC3,SLC47A2,ZNF711,MKRN3,SLC30A4,RNF103,PCDH15,URM1,TRIM16L,MVB12B,FAM13C,MARCH8,ACTR3B" MicroRNA hsa-miR-331-5p:mirSVR_highEffct hsa-miR-331-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.24E-76 2.38E-72 1.90E-75 1.75E-74 198 834 "RALGAPA1,ACADM,NCKAP5,KLHL32,ADCY2,GRAMD1B,PWWP2A,OSBPL1A,C1QTNF3,ALAD,ALCAM,ABCD2,MAP4K3,USP28,PPFIA1,ANXA7,GPAM,TNRC6C,USP37,AQP4,PPP4R4,ARHGAP5,ARRB2,ASGR1,SYNJ1,NAE1,CACNB2,PTBP2,INA,CIART,CASC2,IGFBP7-AS1,FHL5,ABI3BP,IGDCC3,CNRIP1,MFSD4A,CREM,FEZ2,CSNK1G3,KIAA0408,HDAC9,DCAF8,KIAA0513,LONRF1,LIN54,PABPC5,DCC,JAKMIP2,RUSC2,RABGAP1L,NR1D2,DPP6,ARRDC4,ECM2,DNAJB6,DNM1L,ABCC9,RASGRP1,FAM13A,RASA4,PLEKHA1,PAN3,KCNMB2,RABEPK,EPS8,DNAJC27,FAM198B,ZNF461,WAC,ZSCAN30,GORAB,FER,FGF12,FOXG1,SLC37A3,USP16,ATP6V1H,TVP23A,PHYHIPL,ZNF44,TUBGCP4,ARFIP1,GGTA1P,LYVE1,BRD8,GK,HPGDS,TOX3,WDFY3-AS2,EML4,CECR2,GRM1,WIF1,HAS2,ARHGAP19,MIER3,ELOVL5,DHX35,HTR5A,PLD5,LIX1,INSM1,LRRTM3,LAMA2,GPR155,MAP4,IL17D,SHC3,SRSF12,MID1,POC1B,MYCN,NDUFA5,CNOT4,SLC11A2,HCN1,NTRK2,OCRL,LOC100128398,CNTN3,PCSK2,CDK18,PFKFB3,PFKP,ABCB1,ZNF655,A2ML1,HMGCLL1,TRHDE,LRP12,PRRX1,PPP1R1A,RANBP3L,GRAMD1C,RELN,VPS13C,BDNF-AS,TMEM260,PTPRB,RBBP8,RET,ERI2,RNASEL,CCDC102B,MRAP2,LRRK2,LGR4,TRAPPC13,FNIP1,ASRGL1,ASAP3,CPEB3,SLC1A3,BTBD3,DHX30,RUFY2,LRRC55,UNC80,MYT1L,SPART,PBLD,ELOVL4,NUDT10,SYPL1,SYT4,UNC5D,AGTPBP1,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,FAM200B,SIRT1,CRB1,TLR4,KAT6B,CLHC1,PITPNB,ZIC3,LYPD6,CELF4,REEP1,SYNC,ZNF225,RNF103,PPP1R3F,DNAH10,SMIM8,PHTF2,FBXO36,CASC15" MicroRNA hsa-miR-2278:mirSVR_highEffct hsa-miR-2278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.91E-76 2.76E-72 2.19E-75 2.02E-74 221 1030 "CSMD2,AXIN2,KIAA1211,DISP3,LRRC7,ALCAM,BBOX1,OGT,EP400,CNIH2,APC,NT5C3B,LINC00173,CAPRIN2,ASPH,ZBTB10,NCOA1,DDX3Y,ATP2B1,NOL4,ADAM23,BBS2,CFLAR,FUBP1,SCAPER,JAZF1,CACNA1G,CA8,THSD7A,KALRN,PTBP2,CERS5,CDC27,LRRFIP1,KMT2C,NRXN1,COG1,SLC4A8,ZFP28,SNCAIP,CSF1,RGS6,MICAL2,CSNK1E,PDE4DIP,FAM169A,FAM131B,CCDC144A,GAPVD1,CENPL,ZNF337,LONRF1,KCTD8,C8orf34,MYEF2,CHRDL1,EXOG,HS3ST2,DTNB,USH1C,EFNA3,RASA4,ANKRD13B,RABEPK,TAOK3,KIAA1109,FGF11,FHL1,POLK,SYNCRIP,RGPD5,PSD2,APOPT1,PDLIM5,DACH2,ST6GALNAC3,DKK3,GAD1,ZMYND11,DISC1,GATM,GFAP,TCERG1,SPIN1,DCLK2,GNAS,GOLGB1,PRRC2B,PCLO,STMN2,GRIA2,ZNF496,ATXN2L,HLF,MSL1,IGFBP1,RBPJ,USP54,IL11RA,INPP5B,INSM1,KCNC1,KCNC2,KCND1,KCNH2,KIT,LRRC4B,SMAD1,MAP2,LYPLAL1,MARK3,LDLRAD3,MIA2,AFDN,ADAM22,THYN1,MYH6,NAP1L1,NDP,NF1,NHLH1,SMIM11A,NUCB2,PAX6,PBX1,PCMT1,PDGFRA,HERC2P3,CAMKV,KCTD15,PLIN1,PRRX1,NXPH1,PPP2R5C,RANBP3L,PRKACB,PSD,BCAS3,LRRC49,MDGA2,PIGG,CNTLN,PTPRE,CEP97,ZYG11B,RET,FIGN,RPRD1A,ZFHX4,C12orf49,ROBO2,ABCA11P,RYR3,TRAPPC13,SATB1,HOGA1,SCN3A,SCN8A,PRCD,SLC30A10,SEC14L1,COPZ1,PPM1E,FRMPD1,SLC11A1,KBTBD4,CPEB4,RBM34,DOP1A,TRERF1,DOK5,TEX2,PEG10,ZC3H13,NFASC,ZC4H2,MAPK8IP3,ADHFE1,SYNE2,ARHGEF9,SYN2,SYT1,ANKRD28,MTCL1,MCF2L,PDLIM2,CNTN2,ADGRL3,AGTPBP1,TCF7,ZEB1,WDR7,SLC19A3,SIK3,CYB561A3,TEK,AP4E1,BHLHB9,ZFP91,TNR,SMUG1,STXBP4,DCBLD1,RUSC1,KCNE5,SSBP2,TMEFF2,SLAIN1,SLC47A2,ZNF24,ZNF540,CELF4,FTSJ1,SYNC,WNK1,CSDE1,WIPF2,WNK3,SLC17A6,PLSCR4,PHTF2" MicroRNA hsa-miR-892b:mirSVR_highEffct hsa-miR-892b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.05E-76 2.84E-72 2.25E-75 2.08E-74 199 843 "ACADM,ACHE,SORCS1,PWWP2A,KIAA1211,ADORA3,PCDH10,UNC79,FAM135A,AMPH,DPP10,APC,UPRT,PPFIA3,APP,PLA2G4C,PCDHGB4,ATM,ATP1B3,TTLL9,GPR146,MTMR2,MMD2,AP4M1,SRSF11,PLAA,PPT2,NRXN1,DNAJB5,CNN3,SLC4A8,SMARCAL1,AKAP12,NCOR1,VAC14-AS1,DZIP3,ERC2,RIMS2,ZSCAN23,LONRF1,MAML1,MFAP3L,RHOBTB1,DNAH9,DSCAM,MAMLD1,DNAJB6,E2F5,OPTN,IRAK4,ELAVL4,KCNMB2,TMEM74,FGF12,HPCAL4,VTI1B,ANKFY1,SPECC1,CELF1,FYB1,IGSF5,PPARGC1A,RNPS1,ZNF638,CBX1,INSM2,LNX1,PCLO,GRIA2,PRDM5,GRM5,GRM7,KIF3A,ZBTB49,MAP4K5,MUM1,ZHX1,HMGCR,SMAP1,ZNF181,DOCK7,IGSF1,ZNF678,KCNJ3,KCNMA1,CREG2,SYTL4,NCOA7,GPR155,MAP4,SYT9,CCDC80,NAP1L1,NCAM1,NCAM2,TBC1D25,GPR88,OMG,PAK3,PCDHGC3,PRTG,CDK14,PIK3R1,ZFYVE21,EPB41L4B,PCDHB17P,PRKACB,PRKCZ,MAPK10,MDGA2,ELOVL2,PXK,PPP2R3C,ARID4A,SLC6A15,RGS3,EXD2,ROBO1,RPE,TMEM100,ATP8B4,PRR5L,CLIP1,TMEM156,SCP2,ZFP30,SH3GL2,NTNG1,CNKSR2,PPP4R3A,SLC12A4,EFHD1,RIMS1,MBD5,UNC80,UHRF1BP1L,TEX2,IDI2-AS1,CDK19,TSPYL2,TROVE2,SS18,STAU1,TTBK2,VPS13A,SYT1,MTCL1,TAF6,EXOC7,TBX15,EHBP1,ZEB1,RPGRIP1L,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RNF216P1,C18orf54,SLC44A1,TJP1,KCTD2,TSC1,CLHC1,CLDND1,MICU3,MKRN3,EML6,ZNF189,INTS3,CA10,SLC30A4,CADM2,FZD3,KAT6A,PHTF2,JMJD1C,ZNF248,SSPN,RNF146,SLC4A10" MicroRNA hsa-miR-16-5p:Functional MTI Functional MTI miRTarbase 5.85E-76 3.28E-72 2.61E-75 2.40E-74 277 1557 "ABCF1,TKTL1,ACTN1,AXIN2,FZD9,USP31,ADORA2A,PWWP2A,ADORA3,KIDINS220,AP2A1,CASKIN1,HACE1,TBC1D14,AK2,TAOK1,TRMT9B,OGT,ARMC12,GPAM,APP,CDC14B,PDXK,CASK,ARHGDIA,STK33,ASPH,PCDHGB4,ZBTB10,DDX3Y,EIF4G3,DOCK11,BCL7A,SYNJ1,FUBP1,MTMR3,BTRC,FOXK1,CA8,CA12,CACNA2D1,CACNB2,CAMK2G,CANX,MAP7,RUNX1T1,CCNT1,ENTPD6,LONRF2,CDC27,CCPG1,TBRG4,CFL2,DLGAP3,NRXN1,CLU,CLTC,CNN3,TBPL1,BAG4,ACBD5,ZFP28,CRHBP,NCOR2,CSNK1E,OSBPL3,SOCS5,PUM1,RUBCN,ARHGAP32,PHF19,EARS2,RASSF2,RIMS3,PHYHIP,ARMCX2,SPATA2,YTHDC1,ZEB2,MED24,ZC3H11A,G3BP2,DMD,DMPK,USP3,MED12,CPEB2,DMTF1,ACOT8,PDCD6IP,GOLT1B,FCF1,HEYL,SIDT2,EGFR,GOLGA7,EIF4G1,EIF5,PLEKHA1,EIF1,EN2,ANKRD13B,RAB9B,ZNF391,MRPL10,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,TUBB3,DLC1,FECH,SEC24B,FGFR1,CAMSAP1,VTI1B,PDLIM5,CAMKK2,MSANTD4,TPPP3,NEURL4,AHCYL1,NCKAP1,MTHFD2,ZNF559,ATP8A2,RNPS1,RAB30,MSL3,ZNF638,RAB40B,GNAL,ATF7,EML4,TUBA1C,PTPRT,IRAK3,NXPH2,ATXN2L,ELOVL5,NEGR1,DHX35,HSP90AA1,MSL1,IDH3A,RBPJ,IGSF1,DIPK1A,JAK2,KCND3,KIF2A,KIF5A,IPO5,L1CAM,LAMP2,LIG4,ARHGAP12,SMAD1,NAT8L,MAP4,CHIC1,SCAMP5,MOV10,CCDC80,MYO5A,NACA,SLC11A2,OCRL,OGDH,ZNF827,ETFRF1,PCMT1,PDE3B,PDE4D,SERPINE2,CAMKV,PIK3R1,NLE1,PLEC,PRIMPOL,PSAT1,FAT3,PPP2R5C,PRKAB2,CNNM2,PTPRD,TMEM255A,PLEKHB2,ROGDI,RBBP6,SEC61A2,RNASEL,ZFHX4,RNH1,SETD5,EXD2,YY1AP1,TMEM100,FBXW7,SALL1,SARS,SBF1,SOX6,HSPA4L,CPEB3,DHX30,KANSL3,SLC12A2,EPC1,SMARCA4,TTC17,ANKRD36,TMCC1,SON,SOX5,FNBP1,GLT8D1,KIF1B,DDN,LARP4,STAU1,KANK1,GANAB,FAM168A,SYT11,SUPT5H,PRRC2C,DNAJC9,SYPL1,MMS19,DDHD2,TAF9,FAM208A,FBXW11,CLASP1,DOCK9,FRYL,AHCYL2,TEX15,CYB561A3,DICER1,ZMAT3,TGFBR3,ARL10,CABIN1,TPM2,TPM3,ZNF384,NR2C2,RUNDC3B,HSPBP1,TUBB2A,SGK3,CADM1,UBE2H,SLC35A4,AMOT,UGT8,VAV2,WIPF1,CLIP2,KLC2,RICTOR,XPO1,ZBTB16,SLC38A1,CSDE1,XKR7,LMAN2L,TUBA1A,NAV2,WNK3,PLSCR4,RTN4,ACTR3B,AAAS" MicroRNA hsa-miR-374a-5p:TargetScan hsa-miR-374a-5p TargetScan 5.91E-76 3.32E-72 2.63E-75 2.42E-74 160 545 "ABAT,ABR,ACTN1,CSMD2,GRAMD1B,ARHGAP20,PCDH10,ANK3,APC,GAS7,ARHGAP5,ASCL1,PDE8B,NCOA1,ATP1A1,ATP2B2,LDLRAD4,CA12,DCLK1,NOG,NUMBL,CNOT8,JAM2,ABCG2,QKI,HECTD1,NIPBL,IQCK,AKAP6,NRG2,HAPLN1,RNF14,FAM169A,KIAA0408,HDAC9,FRMPD4,PITPNC1,DNAJC6,MFAP3L,BLOC1S6,DLG3,DMD,RCAN1,DYRK1A,EDIL3,SEMA3D,EFNA2,MBNL2,PLXNC1,EIF4G1,EIF4G2,ELAVL4,EN2,EPB41L1,DENND4A,NRN1,ABCA8,FECH,MED12L,FGF12,MEX3B,FOXG1,SEC23B,PSD2,APOPT1,MPP6,NCKAP1,GBX2,AHDC1,PPARGC1A,GPR75,GPT2,NR3C1,FAM19A2,IL1RAPL1,RASSF8,HLF,PLD5,SCIN,BRINP3,METTL21A,KCNN3,KTN1,L1CAM,LSAMP,MAP2,MBNL1,MEIS1,AFF1,MYO9A,NEUROD1,NFIA,NFIX,NKX2-2,NOVA1,NPTX2,OCRL,PAX6,PDE3A,PDE4A,PDE4D,PDPK1,ANLN,FAM216A,PURG,PPP2R2C,PKIA,PTPRG,RAB5B,RALGDS,BSDC1,GTDC1,RFX3,RFX4,PRIMA1,RORB,HUNK,SATB1,CSRNP3,ATXN1,ATXN7,SCN2B,FNIP1,DZIP1,ARHGEF40,BTBD7,CPEB4,MBD5,PDZD2,MYT1L,ERC1,IQSEC2,CDK19,C11orf87,POGZ,LARP4,ANKRD12,CAMSAP2,ATMIN,ACSL6,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,CSMD1,RBFOX2,DOK6,RFTN2,PMEPA1,CADM2,PPP1R3F,RGS7BP,GOPC,FAM13C,KAT6A" MicroRNA hsa-miR-374b-5p:TargetScan hsa-miR-374b-5p TargetScan 5.91E-76 3.32E-72 2.63E-75 2.42E-74 160 545 "ABAT,ABR,ACTN1,CSMD2,GRAMD1B,ARHGAP20,PCDH10,ANK3,APC,GAS7,ARHGAP5,ASCL1,PDE8B,NCOA1,ATP1A1,ATP2B2,LDLRAD4,CA12,DCLK1,NOG,NUMBL,CNOT8,JAM2,ABCG2,QKI,HECTD1,NIPBL,IQCK,AKAP6,NRG2,HAPLN1,RNF14,FAM169A,KIAA0408,HDAC9,FRMPD4,PITPNC1,DNAJC6,MFAP3L,BLOC1S6,DLG3,DMD,RCAN1,DYRK1A,EDIL3,SEMA3D,EFNA2,MBNL2,PLXNC1,EIF4G1,EIF4G2,ELAVL4,EN2,EPB41L1,DENND4A,NRN1,ABCA8,FECH,MED12L,FGF12,MEX3B,FOXG1,SEC23B,PSD2,APOPT1,MPP6,NCKAP1,GBX2,AHDC1,PPARGC1A,GPR75,GPT2,NR3C1,FAM19A2,IL1RAPL1,RASSF8,HLF,PLD5,SCIN,BRINP3,METTL21A,KCNN3,KTN1,L1CAM,LSAMP,MAP2,MBNL1,MEIS1,AFF1,MYO9A,NEUROD1,NFIA,NFIX,NKX2-2,NOVA1,NPTX2,OCRL,PAX6,PDE3A,PDE4A,PDE4D,PDPK1,ANLN,FAM216A,PURG,PPP2R2C,PKIA,PTPRG,RAB5B,RALGDS,BSDC1,GTDC1,RFX3,RFX4,PRIMA1,RORB,HUNK,SATB1,CSRNP3,ATXN1,ATXN7,SCN2B,FNIP1,DZIP1,ARHGEF40,BTBD7,CPEB4,MBD5,PDZD2,MYT1L,ERC1,IQSEC2,CDK19,C11orf87,POGZ,LARP4,ANKRD12,CAMSAP2,ATMIN,ACSL6,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,GPR161,CSMD1,RBFOX2,DOK6,RFTN2,PMEPA1,CADM2,PPP1R3F,RGS7BP,GOPC,FAM13C,KAT6A" MicroRNA hsa-miR-4302:mirSVR_highEffct hsa-miR-4302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.17E-76 3.47E-72 2.75E-75 2.53E-74 189 763 "PLEKHH1,GPR158,OSBPL8,CEP126,KCNT1,MAP4K3,APAF1,ALS2,APOC1,PPP4R4,CADPS,SLC4A4,SLC2A11,ADAM23,TTLL9,BACH1,ZNF599,SCAPER,MTMR2,CA4,CA12,CACNB2,KALRN,PTBP2,VSTM2A,CAST,MTMR7,P2RX6,LRBA,L3MBTL4,ZFYVE9,PLAA,SLC24A2,FHL5,SLC4A7,SLC4A8,ABI3BP,PNKD,PREPL,CREM,CRY2,GDA,CS,NCAN,SLITRK5,UBXN2A,PNPLA8,DCAF4,HDAC9,ARHGAP24,FRMPD4,RASSF2,DAPK1,BLOC1S6,DDX46,RHOBTB1,SMG7,NTM,DMD,NR1D2,DMTF1,DYRK1A,EBF1,KMT5B,ABI2,SIRPB1,CLVS1,PSD2,C2orf88,SORBS1,SMC2,TPK1,STAU2,AP4B1,GABRA2,GAD1,ZNF274,IQGAP2,ZNF559,ARFIP1,CYP46A1,GHR,MALT1,RUNDC3A,GNAO1,CECR2,GRIA4,PRDM5,LINC01551,GUCY1B1,NXPH2,ARHGAP36,CFAP126,KCNJ10,KCNK3,KIF5A,PAXBP1,HECTD2,MARK1,MAT2A,MEIS1,MEIS2,POC1B,CTNNA3,RSPO2,NCF2,VWA2,GPR137C,KCNK10,PDE3A,PDE3B,BEST3,FAM216A,PLCL1,PLXNB1,TRHDE,SEPT4,EPB41L4B,FA2H,MED1,PPP2R5C,PKN2,MAPK4,MASP1,RELN,APTX,SNRK,MTMR10,PTPRG,ZNF844,CEP97,RASGRF1,GTDC1,RFX2,RFX4,RFX5,TTLL7,SLC25A36,RIC8B,RERGL,ELP2,MRAP2,UEVLD,KIAA0895L,RPL38,MEG3,KCNIP1,SATB1,SGK1,ITSN1,SH3GL2,SH3GL3,SHC4,ST6GAL1,SEC31A,SLC6A11,SLC8A1,RAB3GAP1,CXXC4,SMARCE1,MBD5,DOP1A,SOX2,MYCBP2,ATP10B,TROVE2,NKAIN2,SEPT3,STXBP1,SYT1,C12orf76,TBX15,DNAH7,SLC44A1,AMACR,PRR18,ZKSCAN5,TUBB2A,ZNF610,BEST1,ZNF781,SLC38A1,PCDH15,LINC00632,FAM13C,PHTF2,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-620:mirSVR_highEffct hsa-miR-620:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.34E-76 5.25E-72 4.15E-75 3.82E-74 215 981 "CSMD3,ADARB2,ADCY2,PWWP2A,HECW2,CC2D2A,TAOK1,BBOX1,FAM135A,OGT,APAF1,GPAM,MIER1,STK33,CCDC74A,ATP1B3,STX16,B3GALT2,N4BP2L1,ATP6V1G2,ADGRB3,MMD2,CACNA1B,LURAP1,THSD7A,KALRN,LRBA,ARHGEF2,LGI1,MAGI1,UBE2L6,RCBTB2,CASC2,NDST3,LHX2,PCYT1B,SLC35F1,CS,VCAN,NRSN1,ZSCAN23,HDAC9,EARS2,IST1,DAPK1,PITPNC1,ARMCX2,YTHDC1,ELMO1,RHOBTB1,AK5,G3BP2,ZNF582-AS1,HS3ST4,CPEB2,DTNA,ABCC9,AASDH,EDIL3,CNNM1,YAF2,CELSR3,PHF20L1,APH1A,MBNL2,GOLGA7,COPS4,RGS17,TMEM35A,EPHB1,PIPOX,F8,CLVS1,FAM198B,FCGR1A,CEP78,MED12L,FGF13,FGFR1,FOXM1,SPECC1,APOPT1,KHDRBS3,KBTBD12,FYB1,GABBR1,GABRA2,ZMYND11,DNER,MYOZ2,GGT5,PPARGC1A,MALT1,GLI2,GLYR1,PCDH11X,ZNF638,CNDP1,GPR12,MCHR1,NR3C1,GRM7,ZNF496,FAM19A2,RASSF8,HMGCL,AGBL5,SHISA6,CELF5,IRF8,IGFBP1,ZIC5,LRRCC1,DIPK1A,LRRTM3,NME9,JAK2,KCNA4,KCNJ5,MAOB,ERICH3,MSR1,MYO7A,NFE2L2,NTRK2,P2RY1,GLIPR1L2,SNTG1,CNTN3,PRTG,OLA1,HMGCLL1,PMP2,STRN3,NECAB2,EPB41L4B,NXPH1,PRKACB,HYDIN,VPS13C,WDR25,PIGG,BDNF-AS,TMEM260,PTPRD,CASTOR1,PTPRG,PTPRO,C1orf109,DBX2,HKR1,SLC6A15,ZYG11B,GTDC1,RFX4,RGS7,TMLHE,MEG3,LRRTM4,SCP2,COPZ1,NLGN4Y,ZFP30,NTNG1,SHC4,NUBPL,SLC12A4,SPHKAP,SLC22A4,LIMCH1,SNRPN,MYO16,UNC80,SON,PDZD2,HECW1,KDM4C,RBM26,LMO3,CLSTN2,NXT2,STAU1,NUDT10,PLCB1,FAM208A,UNC5D,FBXW11,TMEM136,TBX15,VWA3A,TRIM2,TCF12,SYNE1,FAM189A1,ARHGEF12,DICER1,C18orf54,AP4E1,TJP1,BEX4,TPM1,ANO5,TTTY15,UGT8,OSBP2,USP1,TRIM9,NAV3,EPM2A,GOPC,ST7,PHTF2,RNF170,KLHDC1,GAN" MicroRNA hsa-miR-767-3p:mirSVR_highEffct hsa-miR-767-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-75 6.03E-72 4.77E-75 4.39E-74 204 888 "XKR4,CSMD3,ADAR,ADCY6,ADD1,PWWP2A,ADORA3,SNX32,RTL9,NME5,PPFIA4,PPFIA1,PHYHD1,API5,PPP4R4,ASPH,CHRD,STX16,ATP2B1,N4BP2L1,ADAM23,ZNF599,CFLAR,DST,SGCE,CACNB2,THSD7A,PTBP2,CAMK2G,CBR1,CD86,SRSF11,CNOT8,KMT2C,RAB33A,TJP2,SULT4A1,NIPBL,IGLON5,CNR1,COL4A5,SLC4A8,RBM39,MICAL2,PDE4DIP,ST18,DOCK4,HDAC9,TOX,DGKG,TMEM170A,DNAJC6,TIAM2,FBXL5,SV2B,SRGAP3,EXOG,CDON,PDCD6IP,ABCC5,ABCC9,HIPK3,OPTN,RBM12,EGFR,GOLGA7,EPB41L2,EPHA5,SIRPB1,GMPR2,FAM198B,FDFT1,ZNF589,GTF2IRD2,BAIAP2,POLK,C1orf61,ANKFY1,SLC37A3,COQ5,TACC2,CINP,SMC2,BRPF3,ARPP21,GHDC,MTHFD2,GLS,KDM2B,GPD2,CECR2,GRIA4,GRID1,GRM7,GRM8,RABL2A,NCKAP1L,HPSE2,HTR2A,HTR5A,KCNA4,KIF2A,KLRC2,MAN2A2,ZFYVE27,SYT9,MN1,ZNF680,BLOC1S2,MXI1,NCAM1,NEFH,NEK1,OTOGL,PAK3,PBX1,PDE1A,PDYN,PFKP,ST8SIA5,SMIM7,EPB41L4B,PPM1B,VSTM2L,GRAMD1C,PROX1,SNRK,PIGG,PTCH1,ZIK1,TMEM255A,ARID4A,RADX,SLC6A15,SLC25A36,RNASEL,CARF,CCDC102B,RPE,NEK11,ARMH4,BAALC,ABCA11P,ZNF568,ZNF331,DGLUCY,AMER2,LRRTM4,SCN8A,CPEB3,DOCK10,SEC31A,PAAF1,CCDC88A,ZFP1,IFT122,SNCA,HECW1,KDM4C,ZC3H13,DBNDD2,DDN,TAB2,ZNF302,SSTR2,EPB41L3,NEK4,ADHFE1,AJAP1,FGD4,PRRC2C,ZFR2,SYNE2,VPS13A,SYT4,TAC1,CAMTA1,ANO4,ZEB1,CLASP1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ATP13A2,TK2,HEY2,KAT6B,PRMT8,PPIL6,VLDLR,TBC1D15,GUSBP1,GPR158-AS1,ZNF138,UPF3A,STMN4,PRDM10,TUBA1A,IFT88" MicroRNA hsa-miR-194*:mirSVR_highEffct hsa-miR-194*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-75 6.14E-72 4.85E-75 4.46E-74 169 612 "SERPINA3,ACLY,GRAMD1B,PTCHD1,INTS2,GPR158,HECW2,PITPNM2,AMT,FGD2,UPRT,CACHD1,LGR5,ARRB2,MARCH3,DDX3Y,ADGRB2,LINC00906,AP1M1,KALRN,VSTM2A,CAST,LDB2,CCNH,USP6,AIFM1,CD86,ARHGEF2,CDC42,CDO1,TIGD7,NUMBL,CNOT8,JAM2,TPP1,NIPBL,AKAP5,ACBD5,CPS1,PREPL,RBM39,CRMP1,SNCAIP,SEC24C,DZIP3,ECE2,ARHGAP32,TCAF1,ARHGAP24,DAPK1,SV2A,G3BP2,KBTBD11,HS3ST4,PDCD6IP,MAMLD1,GOLT1B,FRY,FSD1L,PHF20L1,MBNL2,PAN3,EPB41,RASL12,DLC1,RGPD5,EFCAB2,DISC1,KIAA1841,TUBGCP4,LYVE1,ZNF638,LNX1,CCDC184,GRIN1,MUM1,NCKAP1L,LRRC75A,IGSF1,ITGAM,KLC1,SYTL4,MARK1,LYPLAL1,MBD1,TM6SF1,NEK1,NOVA1,LRIT2,TBC1D25,PDGFRA,SEMA5B,PLCB2,PCDH18,PURG,PMP2,MAPKAP1,FSD1,PRKACB,CEP41,PRKCZ,LRRC49,CNTLN,OCIAD1,ZNF615,RAB5B,SH3TC2,RAP1GDS1,ZMAT4,ERI2,GTDC1,RFX4,SEC61A2,YY1AP1,LGR4,RPS20,MEG3,WLS,RYR3,SATB1,CSRNP3,LRFN5,SCP2,FOXRED1,ITSN1,AMBRA1,PAAF1,WDR47,CCDC88A,SPHKAP,SLC22A4,SLN,INTS9,SNRPN,SPP1,TAB2,POGZ,NSFL1C,COBL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FAM200B,MTMR14,BHLHB9,ZFP91,TPD52,TSN,ANKRD20A2,TSC1,UBE2H,BCL2L13,BEST1,PLPP4,ZBTB38,PRDM2,STMN4,PRDM10,SLC17A7,FAM47E,WIPF2,RGS7BP,FZD3,SLC4A10" MicroRNA hsa-miR-138-5p:TargetScan hsa-miR-138-5p TargetScan 1.55E-75 8.71E-72 6.87E-75 6.33E-74 151 486 "ADCYAP1R1,PWWP2A,RNF150,GPR158,ANK1,PPFIA4,GAS7,ARRB1,NCOA1,CCAR2,AZGP1,JAZF1,FOXK1,CACNA1A,CACNA2D1,HAP1,CBFA2T2,CNOT8,KMT2C,NIPBL,IGLON5,NRG2,CLOCK,PLCH2,RIMS4,PLXNA4,FAM169A,PITPNM3,SDC3,RIMS2,HDAC4,KIF26A,RIMS3,MAML1,SCRN1,IP6K1,CTIF,PLEKHM1,MYEF2,NTM,DLG3,CALN1,DNAJB6,EBF1,HIPK3,EFNB3,CELSR3,APH1A,EGFR,PAN3,EN2,RCAN2,GPHN,ANKRD13B,ERBB4,CLVS1,ANKFY1,PSD2,NBEA,CINP,MEGF11,GABRB1,ILDR2,BRPF3,GBX2,AHDC1,PPARGC1A,KIAA1958,FERMT2,PCLO,GRID1,NR3C1,BVES,RASSF8,KLF12,MIER3,CELF5,ATCAY,RBPJ,KCNH1,KCNK3,LIMS1,PPM1L,AFF1,GIT1,MSI1,HS6ST3,PABPC1L2A,NEUROD1,NFIA,NFIX,NNAT,NOVA1,NOVA2,NPTX1,PDE3A,GNG2,CDK14,FSD1,PROX1,RELN,PIGG,PTK2,PXK,NKAIN1,MARCH1,FIGN,ROBO1,RIMKLA,CLIP1,SCN8A,MRAS,HSPA4L,RAB3GAP1,ARHGEF40,KBTBD4,LIMCH1,MAPKBP1,KIF13A,SCN3B,KIF21B,PEG10,IQSEC2,CDK19,CAMTA2,MPRIP,KANK1,NSFL1C,RHBDL3,KIAA0930,GPRIN3,AHCYL2,ARL10,CBX5,ASXL3,DAAM2,KAT6B,CADM1,OSBP2,MGAT5B,LGI4,RGMA,LMAN2L,PPP1R3F,ITM2C,KAT6A,FAM219B,ADAMTSL3,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-767-5p:mirSVR_highEffct hsa-miR-767-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.36E-75 1.33E-71 1.05E-74 9.64E-74 185 737 "KCNH8,NCKAP5,FMNL2,SLITRK1,GALNT13,SLC12A5,PWWP2A,KIAA1324,C1QTNF3,LRRC7,SRPX,FAM135A,SYT13,AMPH,USP28,UPRT,ALS2,CACHD1,CAPRIN2,ASPH,NUMB,STX16,ATP2A2,N4BP2L1,ADGRB3,LINC00847,ARHGEF7,NAE1,CACNA1B,PTBP2,SLC25A14,MTMR7,CDC25B,ARHGAP33,NUMBL,COL4A5,SLC4A8,AHCTF1,ZFP28,CPS1,SEC31B,GDA,CSF1R,CSNK1G3,VAC14-AS1,CTNND2,USP6NL,HDAC9,ZEB2,RHOBTB1,SPOCK3,G3BP2,USP3,TUBD1,EPHA5,ANKRD13B,WAC,SCML2,FER,POLK,MEX3B,FOXG1,ANKFY1,FLYWCH1,JKAMP,CAMKK2,AP4B1,CAB39,ZMYND11,ARPP21,MYOZ2,MSTN,GK,ZNF276,GNAS,GPR37,PCLO,NR3C1,BVES,RNFT2,WIF1,HMGCL,SMAP1,ITGAM,KCNC2,KCNJ11,KCNN2,KCNQ3,LAMA2,PAXBP1,SYTL4,MBNL1,MEST,MTTP,MYCN,MYO6,NASP,NODAL,NTRK2,NUCB2,CLDN11,OXTR,PCDH9,ENPP2,ZDHHC8,GDAP1L1,NALCN,PIK3C2A,A2ML1,PLP1,HMGCLL1,PURG,PMP22,ING3,EPB41L4B,MINDY2,PPP2R2C,PRKAB2,MAPK9,SLC26A11,SAMD9,SNRK,BDNF-AS,SPDL1,PTPRZ1,PTX3,ACSM5,RADX,REV3L,GTDC1,ARHGEF10L,RNASEL,MYH14,ZNF568,SCN3A,HKDC1,ST3GAL3,NUBPL,DHX30,SEPHS1,NAPB,TET1,UNC80,DOP1A,KDM4C,PEG10,SPTAN1,NPAS3,SST,PRRC2C,SYP,KAZN,DDHD2,CAMTA1,CAMSAP2,TCF7L2,WDR7,SYNE1,CYB561A3,TF,CRB1,AP4E1,TJP1,HEY2,TPM1,NPL,TPM2,TRPS1,FNDC5,TUBB2A,UGT8,SLAIN1,PITPNB,VLDLR,WIPF1,ZBTB14,ZNF24,LYPD6,EML6,EMSY,CSDE1,NAV2,CASC15,RNF170,LAS1L" MicroRNA hsa-miR-384:mirSVR_highEffct hsa-miR-384:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.56E-75 1.44E-71 1.13E-74 1.04E-73 210 943 "RALGAPA1,ACTN2,CCDC85A,PLEKHH1,KIDINS220,SLC44A5,TAOK1,ADGRF5,LRRC7,ZNF687,UPRT,API5,PPP4R4,ARNTL,RGS20,ASPH,DOCK11,WASF1,CACNA1D,CACNB2,CALM1,CAMK2D,CCNH,LRBA,L3MBTL4,MAGI1,CCPG1,CHM,NDST3,CLTC,QKI,MAP4K4,NIPBL,TMEM155,CNTN1,FAM149A,ANKRD35,ABI3BP,SLC35F1,PREPL,CREM,ABCG1,APPL1,PHF14,CTH,FRMPD4,ZNF337,DAPK1,ZEB2,POM121,RHOBTB1,SACS,RAB39B,USP3,GOLT1B,EDN1,FAM135B,MBNL2,KMT5B,AASS,RCAN2,IGSF6,CLVS1,FABP7,EFEMP1,TOMM40L,OLFM1,FGF12,FGFR1,UBE2E3,NOP56,SMC2,ATP2C1,FYB1,GABRB1,GALNT15,ZNF234,MTHFD2,GCNT2,GGT7,PPARGC1A,LYVE1,PCDH11X,INSM2,GPM6B,GRIA2,GRIA4,GRID1,ATE1,GRM7,PSIP1,IRF8,NKD1,KNDC1,USP54,LIX1,KCND2,KCNMA1,STMN1,NCOA7,MATN2,MDM4,MEF2C,AFDN,MPP2,ZNF680,MRPL42,NCAM1,NF1,PRTG,SERPINE2,NALCN,PLP1,SMIM7,HMGCLL1,STRN3,EPB41L4B,PPM1B,CRLS1,PRKACB,MAPK9,HYDIN,APTX,SYTL2,DEF8,PSMD13,PTHLH,PTK2,PTN,ZIK1,ZNF615,MSANTD2,RGS12,SEC61A2,ZNF532,ALG9,GSTCD,RORB,PRR5L,TCP11L1,LRRK2,KCNIP1,CLIP1,NCBP3,AMER2,SOX6,FOXRED1,NTNG1,NUBPL,PPP4R3A,SEPHS1,SLC8A1,SLC8A3,CCDC88A,SHANK2,KBTBD4,NAPB,SLC15A2,ANKRD36,LIMCH1,RIMS1,UNC80,SCN3B,TRERF1,GLT8D1,CDK19,TROVE2,ZNF302,NKAIN2,ERBIN,ELOVL4,NEK4,STAC2,NECAB1,PLCB1,SYT4,TACC1,DDHD2,UNC5D,WASHC4,WDR7,DICER1,AP4E1,HEY2,R3HDM1,NPL,AMACR,ANKRD20A2,RFTN2,CADM1,UGT8,SLAIN1,PLEKHH2,CCDC14,P2RY12,PORCN,ZNF19,ZNF32,FMN2,FSTL5,ZNF184,ZNF189,WNK1,PRTFDC1,LINC02210,NAV2,EPM2A,AMN1,HNRNPA3,TTC7A" MicroRNA hsa-miR-583:PITA hsa-miR-583:PITA_TOP PITA 2.68E-75 1.51E-71 1.19E-74 1.09E-73 134 378 "ASIC1,ARID1A,ADCY6,SORCS1,KLHL13,AMPH,APC,PPFIA3,USP37,CASK,MARCH3,DACT3,ZBTB10,CCAR2,SLC4A4,ATP1B3,ATP2B3,NOL4,BSN,LDLRAD4,CACNA1E,THSD7A,MAP7,SEPT7,REPS2,CDC42,MAGI1,FOXN3,LHX2,CLCN3,CLTC,SLC25A27,BAG4,SEC24C,RIMS4,SLITRK5,DOCK4,GAPVD1,ZFYVE16,DBN1,ELMSAN1,CEP170,SMG7,G3BP2,NR1D2,CPEB2,DYRK1A,SNX29,FAM135B,PHC2,EFNA3,ABI2,ELAVL2,EN2,EPB41L2,ERBB4,WAC,IP6K2,AFF2,NBEA,SORBS1,FAM49B,NPTN,FUT9,FYN,GALC,GAP43,C15orf41,MMADHC,PRRC2B,GPD1,RNF165,FAM107A,BACH2,GABARAPL2,NEGR1,ZIC5,KCNA1,CAMK2N2,MAT2A,CHIC1,LRP1B,MEIS1,MN1,MXI1,NEXMIF,ZC3H12B,NF1,CNOT4,HCN1,PIK3C2A,ST8SIA5,PLP1,LRRN3,PPP2R5E,PPP3CA,OXR1,RYR3,ATXN1,LRFN5,KIF16B,CPEB3,NTNG1,SHMT2,SLITRK3,NLGN1,PPP4R3A,SLC11A1,SLC12A2,CPEB4,SON,KIF21B,NPAS3,SRPK2,NKAIN2,ERBIN,VAMP1,PLCB1,CUX2,RPGRIP1L,PUM2,RBFOX2,TRPC1,TRPS1,FNDC5,SSBP2,CADM1,UBE3A,ZFAND5,CA10,NAV3,WNK3,KAT6A,CBLN2" MicroRNA hsa-miR-124:PITA hsa-miR-124:PITA_TOP PITA 4.13E-75 2.32E-71 1.83E-74 1.68E-73 181 708 "ACHE,FMNL2,SLC12A5,SORCS1,ESYT2,CASKIN1,PCDH19,OSBPL8,SEMA6A,ZNF687,LRFN1,GPAM,CHRD,DDX3Y,ATP1A1,DPY19L3,BCL7A,DCAF5,NIPA1,PTBP2,ARHGEF1,TMEM257,CDH2,LHX2,TJP2,QKI,AKAP6,MYRIP,PNKD,CLOCK,CLIP3,LRIG1,SOCS5,SLITRK5,PLCXD3,CTNND1,EDRF1,MYADM,GAPVD1,HDAC4,PHF19,KIF26A,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,BLOC1S6,SPOCK3,G3BP2,GRIN3A,RCAN1,TOM1,E2F5,HIPK3,FSD1L,RBM12,EFNB3,TENM1,PAN3,EPS8,REEP2,PRKAG2,SUCO,PCYOX1,GABRB3,GABRG2,IQGAP2,ARFIP1,PCDH17,GLRB,KIAA1958,GPT2,GPD2,RAPGEF1,GRIA2,GRIA4,GRID1,RFFL,GSN,KIF3A,RNF165,KAT7,ARHGAP19,BACH2,NEGR1,MYLK2,INSM1,ITGA7,KCNA1,KCNA6,KCNK2,KIF2A,MAT2A,CHIC1,POC1B,MITF,MTR,MYO9A,NAP1L3,NFIX,NHLH1,NME4,NRCAM,NUMA1,KCNK10,PCDH8,PCDH9,PDE4B,PDE4D,GDAP1L1,PIK3C2A,RETREG1,XRN1,PLEC,SMOX,ANKRD16,PRRX1,EPB41L4B,SH3KBP1,PKN2,TMEM104,MTMR10,TMEM260,PTPRD,PTPRZ1,RALGDS,ZYG11B,DUSP15,UBR7,SOX8,CLIP1,RYR1,RYR3,SEMA6D,SCN2B,SCN4B,SCN7A,CASC3,GALNT10,SGK1,KIF16B,SHC4,SLITRK3,FAM81A,SLC12A2,ATF7IP,TET1,SLIT1,PALLD,ZCCHC24,FNBP1,LMO3,ITPRID2,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TCF4,TMOD1,NR2C2,TUB,CADM1,SLC35A4,UBE3A,AMOT,USP1,WIPF1,CLDND1,SMARCAD1,WNK1,PMEPA1,PRDM2,EVI5,LMAN2L,WIPF2,TMEM63C,FXR1,ST8SIA2" MicroRNA hsa-miR-554:mirSVR_lowEffct hsa-miR-554:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.11E-75 2.87E-71 2.26E-74 2.08E-73 203 887 "SERPINA3,EMILIN3,CSMD3,FMNL2,KLHL32,TMEM132B,GALNT16,ADCY6,GRAMD1B,MTUS1,KLHL13,CEP126,FAM135A,CNIH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APAF1,KIAA1614,TMEFF1,CARMIL3,BMPR1B,SCAPER,BTRC,LURAP1,CAMK2A,CAMK2D,TRIM41,CARS,ISPD,PRC1,KYAT1,CD38,C1orf52,LRBA,CDH2,CDO1,RAB3C,JAM2,KIAA1549L,TJP2,QKI,RCHY1,ACBD5,CPS1,AKAP12,NCOR1,CSF2RA,SOCS5,FAM169A,PLCXD3,NOS1AP,CYBB,CENPL,EARS2,SCRN1,JAKMIP2,MFAP3L,FBXL5,SV2A,FAM107B,NYAP1,ABCC9,EDNRA,FSD1L,EFNA3,YAF2,TUBD1,IGSF6,EFS,MRPL37,EZH1,TAOK3,FCGR1A,IP6K2,FLT1,RASL10A,CELF1,SARAF,GABRA1,ZMYND11,ARPP21,TUBGCP4,GGT7,KIRREL3,DIDO1,KAT7,C1orf94,ARHGAP19,VSIG4,GABARAPL2,SYNPO,ZNF491,LRRCC1,USP54,LIX1,KCNMA1,CREG2,KIF2A,STXBP5,PAXBP1,SYTL4,MAG,MAOB,SYT9,SHC3,MEIS1,KCTD6,POC1B,MITF,NRBP2,FXYD6,PDE2A,PDGFRA,PFKFB2,GDAP1L1,A2ML1,PKD1,LRRN3,PPP2R5C,PPP3CA,PPP3CB,EPDR1,LRRC49,CNTLN,UHRF1BP1,PTHLH,PEX5,TMEM231,PPP2R3C,USP47,FAM66C,ZNF793,SH3TC2,RASGRF1,ARID4A,FIGN,RFX5,CCDC82,ALG9,CARF,RORB,SPIN3,RTKN,SALL1,MAPK12,SATB1,KIF21A,ASAP3,ST3GAL3,SLA,KDM4B,SON,TNIK,KIF21B,ERC1,DDN,STOX1,FGD4,VPS13A,SYPL1,ANKRD28,VWA3A,TCF4,SATB2,TPCN2,DOCK9,C18orf54,GPR161,TMEM9,HEY1,DDHD1,TLL2,NR2E1,ERCC6L2,HEY2,R3HDM1,RGMB,NR2C2,TRIO,TSC1,TMEFF2,HIRA,FLRT2,FLRT1,PLEKHH2,ZNF709,BCL2L13,VSNL1,RICTOR,ZNF24,ZNF74,ZBTB38,TMEM237,POLR3H,ZXDA,PRDM2,NAV3,EPM2A,ADAMTSL3,NHSL1,SLC39A12,NETO1,SLC4A10" MicroRNA "GTGCCTT,MIR-506:MSigDB" "GTGCCTT,MIR-506:MSigDB" MSigDB 7.81E-75 4.39E-71 3.45E-74 3.18E-73 176 672 "FMNL2,SLC12A5,SORCS1,PLEKHH1,ESYT2,CASKIN1,PCDH19,OSBPL8,AK2,SEMA6A,ZNF687,GPAM,CDC14B,SFMBT2,CHRD,DDX3Y,ATP1A1,DPY19L3,DCAF5,NRP2,NIPA1,MYRF,PTBP2,USP6,TMEM257,CDH2,LHX2,TJP2,QKI,TMEM184B,ARHGEF6,AKAP6,MYRIP,CLOCK,LRIG1,GALNT9,SOCS5,SLITRK5,PLCXD3,CTNND1,EDRF1,HDAC9,MYADM,GAPVD1,HDAC4,PHF19,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,BLOC1S6,SRGAP3,GRIN3A,DNM2,RCAN1,E2F5,EDNRB,RBM12,EFNB3,PAN3,EPS8,EYA1,SUCO,PCYOX1,IQGAP2,SEPT9,ARFIP1,KIAA1958,GPT2,GRIA2,GRID1,RFFL,CACFD1,NR3C1,KIF3A,RNF165,KAT7,BACH2,NEGR1,MYLK2,INSM1,ITGA7,KCNK2,HECTD2,MAT2A,MITF,JAKMIP3,MTR,NAP1L3,NFIX,NHLH1,NME4,NRCAM,NUMA1,KCNK10,PCDH8,PCDH9,PDE4B,GDAP1L1,RETREG1,XRN1,PLEC,SMOX,PRRX1,SH3KBP1,MAPK7,MDGA2,TMEM104,PTPRZ1,USP47,RAD17,RALGDS,DUSP15,RFX4,UBR7,SOX8,RXRA,RYR1,RYR3,SEMA6D,SCN2B,SCN4B,SMPD3,GALNT10,SGK1,KIF16B,SHC4,SLITRK3,FAM81A,ARHGEF40,SHANK2,SLC12A2,BTBD7,ATF7IP,SLIT1,LIMCH1,PALLD,ZCCHC24,KIF21B,FNBP1,LMO3,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TPCN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMOD1,TPD52L2,NR2C2,SLC35A4,UBE3A,AMOT,USP1,CLDND1,USP32P2,FSTL5,ZNF189,SPIRE1,ZNF213,SMARCAD1,PRDM2,EVI5,ADAMTS9,ITM2C,TMEM63C,ST8SIA2" MicroRNA hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA_TOP PITA 9.20E-75 5.17E-71 4.06E-74 3.74E-73 128 345 "XKR4,SLITRK1,ADD3,LRFN2,PCDH19,SEMA6A,TRMT9B,MAP4K3,FAM131A,CACHD1,TMEFF1,ARHGAP5,CAPRIN2,NCOA1,ATP2B1,NOL4,CDK5R1,BTRC,LURAP1,SYT6,SEPT7,CDH10,LGI1,DLGAP2,FOXN3,SYNPR,B4GALT6,AKAP6,CLOCK,SNCAIP,TENM4,SOCS5,ERC2,RIMS2,SPOCK2,ARMCX2,ALKBH8,POM121,DLG2,CPEB2,FRY,MBNL2,EIF4G1,ELAVL2,EPHB1,ERBB4,EYA1,TAOK3,ATP8A1,FGF13,ACTL6B,PRKAG2,FHL1,UBE2E3,MEX3B,FAM49B,FUT9,GAB1,GABRB3,NCKAP1,WASF3,SPIN1,GLS,PCLO,GRM3,MIER3,HNF4G,JAK2,KCNA6,KCNJ3,KCNMA1,PACRG,MARK1,MAT2A,AQP11,LRP1B,KITLG,MSI1,HS6ST3,RTL5,NAP1L3,NFE2L2,NTRK2,PDGFRA,PDPK1,GNG2,MED1,DIRAS2,RELN,TMEM260,FAM120C,TMEM255A,RAP1GDS1,MSANTD2,FIGN,UEVLD,SCN2A,PPM1E,CPEB3,RIMS1,SNAP25,TMCC1,FAM126B,SOX11,SP4,ZNF423,MAPK8IP3,FAM168A,SYP,WSCD1,TRIM2,PUM2,TPM3,TRPS1,UBE3A,FLRT2,ZIC2,ZIC3,ZNF24,ZBTB38,ZFAND5,PMEPA1,CADM2,LMAN2L,ADAMTS9,WIPF2,SLC17A6,NETO2" MicroRNA hsa-miR-31*:mirSVR_lowEffct hsa-miR-31*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.21E-74 6.77E-71 5.31E-74 4.89E-73 207 925 "TTYH1,ACLY,SYS1,KLHL32,ADD2,PLEKHH1,RNF150,ADGRF5,LRRC7,SYT13,LRCH2,ANK3,PPFIA4,ANXA7,APBB2,EPB41L5,CDC14B,MIER1,ATP2A2,MYOM1,BCL2L2,C5,NIPA1,OSGIN2,CALB1,MAP7,CDH2,ZMYM4,MAGI1,CHM,RAB33A,FAM19A5,IGLON5,COL9A3,RCHY1,MFSD4A,CREB5,CTH,ZSCAN23,DCAF4,CYBB,TOX,LONRF1,MAML1,DGKB,DGKG,C8orf34,MYEF2,BLOC1S6,SGSM2,HS3ST4,DYNC1I1,CDON,DYRK1A,ABCC5,HIPK3,CNNM1,SH3GLB1,ING4,ELAVL4,EPS8,EYA1,KIAA1109,FGF12,FGF13,POLK,CAP2,PCYOX1,TACC2,TMEM107,PDLIM5,STAU2,ERAP1,GATM,ALDH1L1,TTBK1,GLRB,KDM2B,MAP7D2,GPR22,DIDO1,MFSD2A,PSIP1,WIF1,HPS5,SCRG1,SYNPO,OPALIN,DHX35,SMAP1,MSL1,FAM95B1,IGF1,DOCK7,IL12A,ZNF385B,SLC35G1,KCNA4,KCNA6,KCNK1,KCNK2,KIF5A,IPO5,LAMP2,HECTD2,MARK1,MBNL1,SYT9,SRSF12,MITF,MSI1,CTNNA3,MYO6,NAP1L3,NEK1,NF1,NFIA,P2RY1,CNTN3,ETFRF1,PCDH9,PDCD2,SSH1,CCSER2,NLE1,HMGCLL1,STRN3,EPDR1,DIRAS2,PSMD13,CNTLN,PTCH1,ELOVL2,PXK,TMEM260,PTPN13,PTPRE,QDPR,PLEKHB2,ENOX1,OXR1,KHDRBS2,RNASEL,LGI2,CCDC82,DCUN1D2,TMLHE,BAALC,KIAA0895L,KCNIP2,RXRA,RYR3,FAM192A,RMI1,LRRTM4,SEC14L1,GALNT10,HSPA4L,SH3GL3,NTNG1,FBXO11,SLC2A5,DHX30,KANSL3,SLC8A3,MBD5,SNRPN,PALLD,MYT1L,BDP1,KIF1B,SPART,C11orf87,KLHL7,ARHGEF9,SYT1,MTCL1,DDHD2,KIAA1107,TMEM136,KLHL4,DMXL2,CLASP1,WDR7,DOCK9,USP32P1,ZFPM2,AP4E1,TIAM1,DDHD1,BHLHB9,KCTD2,CDK20,C9orf85,TSN,RPL7L1,WRN,ZNF24,TRIM9,XKR7,ADAMTS9,NAV2,PARP11,PDSS2,PHTF2,FXR1,ST8SIA2" MicroRNA hsa-miR-938:mirSVR_lowEffct hsa-miR-938:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-74 7.47E-71 5.86E-74 5.40E-73 195 825 "RNF157,PWWP2A,PTCHD1,HECW2,KIAA1324,AK2,ZNF578,HFM1,C1QTNF3,ALCAM,ZFAT,ANK3,FAM131A,AQP4,CDK13,MARK4,BCL2L2,BID,CFLAR,CACNA1D,KALRN,RUNX1T1,USP6,TMEM257,LGI1,CHGB,IGFBP7-AS1,CLCN4,SRP14-AS1,AKAP6,RCHY1,CREB5,HAPLN1,OSBPL3,RIMS4,CNTNAP2,RHOBTB1,SMG7,USP3,DPH1,DRD1,ECM2,DNM1L,E2F6,WDPCP,FRY,PHF20L1,KCTD3,EPHA5,RTN3,DUSP27,ACSL4,ZSCAN30,GORAB,FGF14,PCYOX1,C2orf88,PDLIM5,ATP2C1,ZNF605,CELF1,NRG3,TVP23A,HBS1L,AHCYL1,BRPF3,JPH4,NEK6,ALDH1L1,ZNF638,RAB40B,PRUNE2,NUDT21,RFFL,GRIK4,GRIN2C,AP4S1,PSIP1,GABARAPL2,AGFG1,HSPA1L,SHISA6,LIX1,GPR62,KCNK1,KHK,KIF2A,KIF5A,SYTL4,FGFBP3,PIK3AP1,LOC100128239,MBD1,SYT9,IL17D,LRP1B,MEIS1,MEIS2,MGAT3,MID1,AFDN,ERICH3,MTTP,ZNF862,ALDH1L2,CNOT4,PCSK5,GPSM2,PLXNB1,LRP12,EXOSC10,PPP3CB,RASGEF1B,PKIA,EPDR1,GDPD2,SNRK,TMEM260,PTPRB,OCIAD1,C1orf109,RIPOR1,ZSCAN2,RAB5B,RADX,GAL3ST4,TRIM68,RGS4,CCDC102B,GLDN,LRRK2,ATAT1,NCBP3,CSRNP3,SCN2B,NLGN1,WDR37,EPN2,DHX30,SLC6A1,SLC6A11,SEPHS1,SLC9A5,CXXC4,UNC80,SCN3B,WDTC1,SOX2,SOX11,HECW1,ATP10B,CLSTN2,SS18,CEP68,MTCL1,PDLIM2,UNC5D,TMEM136,KLHL4,TCF4,TPCN2,TRIM2,WASHC4,SYNE1,RALYL,USP32P1,FAM200B,FBXL16,TK2,RIMBP2,KAT6B,TNR,RGMB,PRMT8,TRPS1,FNDC5,UBE3A,PLPPR2,VAV2,RBFOX3,RICTOR,LGI4,TMEM237,SPIRE1,FTSJ1,PMEPA1,SCG2,GAL3ST3,MVB12B,FAM13C,CASC15,CAMK1G,SSPN,FRMD6,SLC4A10" MicroRNA hsa-miR-512-3p:mirSVR_highEffct hsa-miR-512-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-74 8.80E-71 6.89E-74 6.35E-73 190 785 "KCNH8,NBAT1,KLHL32,KIAA1211,PTCHD1,FAHD2CP,AK2,SPOP,PCDH10,PPFIA2,APC,UPRT,TNRC6C,LGR5,DST,SYNJ2,PTBP2,CCKBR,MTMR7,LRBA,RCBTB2,B4GALT6,TJP2,ABCG2,QKI,ARMC8,SUMF2,LETMD1,SLC4A7,SLC4A8,MFSD4A,ENTPD4,CRHBP,ABCG1,ARHGEF10,CTH,GREB1,BOC,HDAC9,TOX,ZFYVE16,DBI,ZNF804A,HP1BP3,HS3ST2,USP3,FAM78B,DNM1L,EDNRA,EDNRB,HIPK3,EFNA3,PHF20L1,MBNL2,RTN3,FER,FGF13,POLK,SUCO,C2orf88,DACH2,OGA,PHYHIPL,ILDR2,ERAP1,DISC1,MSTN,PPARGC1A,GLUL,DCLK2,LOXL3,GNAS,GRIK3,LINC00839,PSIP1,LINC01102,HTR2A,HTR5A,MSL1,RAB41,SLC35G1,KHK,STXBP5,NCOA7,SMAD9,MAN2A2,MAT2A,MBNL1,SYT9,MTR,MXI1,NEK1,NFE2L2,PAK3,PDCD2,PRTG,PFKP,NALCN,PKD1,PLXNB3,TRHDE,LRP12,PPP2R5E,PPP3CA,PKIA,MAPK10,GRAMD1C,HYDIN,MDGA2,TMEM260,PTPRG,PTPRO,PEX2,FAT4,RAP1GDS1,ENOX1,SLC6A15,RFX3,RFX4,RPRD1A,CARF,ROBO1,RORB,RPS20,SYNDIG1,SALL1,SEMA6D,ATXN7,SCN2A,TNFRSF19,SHC4,MAGI3,CHD9,ATF7IP,ZFP1,IFT122,FAM219A,SON,MYT1L,SP2,CLASP2,TROVE2,LRRC4,SS18,ADHFE1,FNDC9,C12orf76,TAC1,KAZN,CAMTA1,ATMIN,ZEB1,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,CRB1,ITGB3BP,AKTIP,NR2E1,PIK3R5,TPM1,NPL,TRO,UGT8,GUSBP1,ZNF711,FMN2,PLPP4,ZSCAN26,ANKS1B,PLPPR5,ZNF213,CADM2,PCDH15,MVB12B,NELFE,EPM2A,MARCH8,UBE3B,KAT6A,JMJD1C,ZNF248,SLC4A10,ZNF30" MicroRNA hsa-miR-506:PITA hsa-miR-506:PITA_TOP PITA 1.70E-74 9.57E-71 7.49E-74 6.90E-73 180 706 "ACHE,FMNL2,SLC12A5,SORCS1,ESYT2,CASKIN1,PCDH19,OSBPL8,SEMA6A,ZNF687,LRFN1,GPAM,CHRD,DDX3Y,ATP1A1,DPY19L3,BCL7A,DCAF5,NIPA1,PTBP2,ARHGEF1,TMEM257,CDH2,LHX2,TJP2,QKI,AKAP6,MYRIP,PNKD,CLOCK,CLIP3,LRIG1,SOCS5,SLITRK5,PLCXD3,CTNND1,EDRF1,MYADM,GAPVD1,HDAC4,PHF19,KIF26A,MAML1,DAPK1,SPOCK2,AIF1L,ELMSAN1,BLOC1S6,SPOCK3,G3BP2,GRIN3A,RCAN1,TOM1,E2F5,HIPK3,FSD1L,RBM12,EFNB3,TENM1,PAN3,EPS8,REEP2,PRKAG2,SUCO,PCYOX1,GABRB3,GABRG2,IQGAP2,ARFIP1,PCDH17,GLRB,KIAA1958,GPT2,GPD2,RAPGEF1,GRIA2,GRIA4,GRID1,RFFL,GSN,KIF3A,RNF165,KAT7,ARHGAP19,BACH2,NEGR1,MYLK2,INSM1,ITGA7,KCNA1,KCNA6,KCNK2,KIF2A,MAT2A,CHIC1,POC1B,MITF,MYO9A,NAP1L3,NFIX,NHLH1,NME4,NRCAM,NUMA1,KCNK10,PCDH8,PCDH9,PDE4B,PDE4D,GDAP1L1,PIK3C2A,RETREG1,XRN1,PLEC,SMOX,ANKRD16,PRRX1,EPB41L4B,SH3KBP1,PKN2,TMEM104,MTMR10,TMEM260,PTPRD,PTPRZ1,RALGDS,ZYG11B,DUSP15,UBR7,SOX8,CLIP1,RYR1,RYR3,SEMA6D,SCN2B,SCN4B,SCN7A,CASC3,GALNT10,SGK1,KIF16B,SHC4,SLITRK3,FAM81A,SLC12A2,ATF7IP,TET1,SLIT1,PALLD,ZCCHC24,FNBP1,LMO3,ITPRID2,PHLDB1,KANK1,PLCB1,SYPL1,CAMTA1,TAL1,TCF4,TMOD1,NR2C2,TUB,CADM1,SLC35A4,UBE3A,AMOT,USP1,WIPF1,CLDND1,SMARCAD1,WNK1,PMEPA1,PRDM2,EVI5,LMAN2L,WIPF2,TMEM63C,FXR1,ST8SIA2" MicroRNA hsa-miR-539:PITA hsa-miR-539:PITA_TOP PITA 4.55E-74 2.56E-70 2.00E-73 1.84E-72 149 483 "ACTN1,NDRG3,DSCAML1,ERMN,ADRA1B,PCDH19,LRRC7,SPOP,FAM135A,AMPH,ZBTB10,NCOA1,CCAR2,DDX3Y,ATP2A2,ATP2B1,BCL7A,BSN,BTRC,RUNX1T1,ZMYM4,CACNA2D2,CFL2,FOXN3,NMT2,CNN3,CNR1,CNTFR,ZNF521,SEC24C,SOCS5,SLITRK5,CTNND1,FRMPD4,IP6K1,DBT,HP1BP3,KLHL3,SRGAP3,HS3ST4,RBM12,YAF2,APH1A,TENM1,TMEM35A,PAN3,RCAN2,EPHB1,ERBB4,ETV1,NRN1,F5,SCML2,FGF13,PRKAG2,CAMSAP1,FOXO3,FYN,MEGF11,DNER,MMADHC,PPARGC1A,GK,RAB30,TOX3,PCDH11X,GNAO1,GPM6A,NUDT21,GRIA2,GRM1,RNF165,KAT7,CELF3,KLF12,BACH2,HNRNPK,OLFM3,KCND2,KCNK1,SFXN5,MAP2,CHIC1,MITF,RSPO2,HS6ST3,NEXMIF,TCEAL5,NCAM1,NELL2,NFIA,NKX2-2,NPTX1,HCN1,NLGN3,NALCN,XRN1,PDZRN4,SPATA6,MED1,RANBP3L,ELOVL2,PTK2,FAM120C,PRRT2,FIGN,ZFHX4,ZNF532,FNIP1,ELMOD1,PPM1E,NTNG1,CHD9,R3HDM2,PKNOX2,TET1,SNCA,FAM126B,SOX5,SOX11,ARHGAP26,ZBTB43,CLASP2,LARP4,STAU1,SYN1,TAC1,POPDC3,CAMSAP2,FBXW11,TCF4,TCF7L2,TRIM2,RPGRIP1L,TCF12,WDR7,PUM2,ZFPM2,CBX5,HEY2,RPRM,FAM155A,UBE2H,SF1,ZIC1,SMARCAD1,SLC30A4,CADM2,SCG2" MicroRNA hsa-miR-362-5p:mirSVR_highEffct hsa-miR-362-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.13E-74 2.88E-70 2.25E-73 2.07E-72 186 758 "SYS1,AP2A2,LRRC7,BCAR3,ANK3,ALS2,AQP4,ALDH4A1,ATP1B3,NOL4,ADAM23,LINC00847,CFLAR,CASTOR3,CALB2,CAMK2B,CAST,CCNH,USP6,LRBA,CLGN,COPB2,NRXN3,TPP1,NMT2,AKAP6,RBM39,RNF14,UBXN2A,ZFYVE16,KIAA0586,PITPNC1,ZEB2,KIAA0753,DDX46,RABGAP1L,DNM1,USP3,DNM2,CASP8AP2,ACOT8,PDCD6IP,ABCC9,WDPCP,SEMA3D,KLHL5,APH1A,ELAVL2,KCNMB2,CEP85L,ADGRV1,F8,CLVS1,TAOK3,CORO2B,KIAA1109,SEC23B,SGIP1,PDLIM5,ZNF605,CELF1,NRG3,GALNT15,GABRG2,RAPGEF6,C15orf41,ADAM28,FREM1,TXNL4A,COPS8,DBF4,ZNF638,KDM2B,KCNMB4,LILRA1,GSTT2,KLF12,MIER3,AGBL5,HNMT,USP51,HSP90AA1,SMAP1,IGF1,SCIN,ZNF385B,JAK2,SLC35G1,OLFM3,KCNH2,KCNMA1,MKLN1,MMP16,ERICH3,ADAM22,RSPO2,NAP1L2,NEUROD1,CNOT4,GPR88,SNTG1,PCSK5,PDCD2,RETREG1,PLCD1,JAKMIP1,PRIMPOL,STRN3,PILRA,PPM1B,PRKACB,EPDR1,HYDIN,CNNM2,PSMD13,CNTLN,BDNF-AS,PTHLH,TMEM260,OCIAD1,PTPRD,PTPRE,CEP97,REV3L,RFX4,SEC61A2,SLC25A36,SETD5,ARMC5,CCDC102B,RPE,BAALC,TCP11L1,ATAT1,RMI1,SATB1,LRRTM4,FAM19A1,CASC3,KIF21A,ITSN1,ST6GAL1,PAAF1,ZNF365,SEPHS1,NAPB,CXXC4,ANKRD36,MBD5,ZNF415,SNRPN,KDM4B,USP33,KDM4C,NKAIN2,ADHFE1,STXBP1,NUDT10,TACR1,MTCL1,ANO4,ATMIN,TCEA1,AKNA,FRYL,C18orf54,AP4E1,TLR4,NR2E1,ERCC6L2,C5orf64,CDK20,RUNDC3B,TUBB1,UGT8,ZNF709,PCDH20,MICU3,KCNT2,CELF4,SYNC,SEMA3B,SLC17A7,FZD3,FBXO36,ADAMTSL3" MicroRNA hsa-miR-4278:mirSVR_lowEffct hsa-miR-4278:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.63E-74 4.28E-70 3.35E-73 3.08E-72 190 792 "TTYH1,ABAT,ACHE,XKR4,RNF157,ADD2,ERMN,ADRA1D,LRFN2,SNX32,CC2D2A,UNC79,MRTFA,ZNF687,DPP10,PPFIA1,DGKZ,UPRT,FAM131A,CASK,RASL11B,ATP2B2,ADAM15,GPR146,SYNJ2,BTK,WASF1,MYRF,TMEM257,CDH18,EVI5L,LOC730101,TIGD7,UBE2L6,CHGA,CASC2,SYNPR,NDST3,LSMEM2,NRXN3,ZFYVE9,COG1,SLC35F1,SNCAIP,CSF1,TENM4,ATRNL1,SDC3,CX3CR1,NOS1AP,CYBB,HDAC9,ARHGAP32,COPS7A,KLHL3,TMEM130,SMG7,SRGAP3,DMD,RPS6KL1,SLC12A6,FAM57B,DPYSL2,ACOT8,GNE,PHC2,CELSR3,GOLGA7,TENM1,EMX2,ZIC4,EFEMP1,CHST15,TESK2,KAT8,SLC9B2,SEMA4D,SGIP1,MEGF11,GAD2,AHDC1,ADAM28,PPARGC1A,MALT1,GLS,GNAS,FERMT2,GPT2,STMN2,C1QL4,GRM3,RABL2A,FAM107A,CELF3,ARHGAP36,ELOVL5,HMGCL,AGBL5,HNRNPK,LRRC75A,SCIN,KCNH1,KCNJ10,KCNN2,KIF5C,HECTD2,SHC3,MEIS2,MPP2,JAKMIP3,BLOC1S2,NEFH,NPTX1,NRCAM,SMIM11A,NTRK3,ZDHHC22,PCDH8,PCSK5,MAPKAP1,PTPA,PPP5C,MASP1,SAMD9,SLC22A23,PTHLH,PTPRN,PTPRN2,RAB5B,ROGDI,ZYG11B,PRRT2,UBR7,RAVER2,EPHA10,RYR1,SOX6,GALNT10,SFPQ,FUZ,SHMT2,BCAN,SLC6A7,SLC11A1,SLC14A1,SLCO1A2,ABTB1,SMARCD3,SOX2,BDP1,ZSWIM8,ZC3H13,SPTAN1,SPART,ZC4H2,TTBK2,SYT11,ARHGEF9,NUDT10,KAZN,CLASP1,SZT2,PCDHB9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZMAT3,AKTIP,FBXL16,THRA,DDHD1,R3HDM1,SSBP2,CLEC2L,UBTF,NSD2,ATP6V0E2,NDRG4,LYPD6,CELF4,MEIS3,EMSY,FAM13C,FAM219B,MSRB3,CBLN2" MicroRNA hsa-miR-220c:mirSVR_highEffct hsa-miR-220c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.98E-74 4.48E-70 3.50E-73 3.22E-72 188 776 "ASIC2,CLK4,TKTL1,ARID1A,NLGN4X,KCTD16,AK2,LRRC7,FAM135A,PHF12,SUGT1P4-STRA6LP-CCDC180,PARG,CDK10,DACT3,CHID1,ATP2A2,ATP6V1G2,ADAM23,LINC00847,ZNF599,OSGIN2,CFL2,SRSF11,SOCS6,CHN2,CLTA,CNGA3,AKAP6,COL4A5,MAGED1,ENTPD4,ANKRD44,GDA,RGS6,ATRNL1,VAC14-AS1,SLITRK5,CTNND1,PUM1,DAPK1,HP1BP3,RHOBTB1,SMG7,HS3ST2,USP3,CPEB2,DPP6,ARRDC4,AASDH,EDIL3,EDNRB,RASGRP1,SEMA3D,PAN3,F8,ZSCAN30,POLR1B,FHL1,IP6K2,DCTN2,GABBR1,GABRB1,GALC,ERAP1,SIGLEC8,TUBA8,ADAM28,GJB1,DHRS4,GPD1,GPM6A,FUT10,GRID1,GRIK2,GRM7,FAM19A2,ADAMTS6,MIER3,RBPJ,USP54,ZNF678,ITGA7,KCND3,ARHGAP12,NAT8L,MAN2A2,SYT9,MDM4,KCTD6,PPM1L,MT3,MYO7A,PABPC1L2A,NKX2-2,NPY,SMIM11A,NUCB2,IGSF11,GLIPR1L2,PCSK2,PDE4B,PFKFB2,GDAP1L1,A2ML1,FTO,PLXNB1,SEPT4,SLC36A4,PTPA,KANSL1,BCAS3,PTCH1,OCIAD1,PTPRG,PTPRZ1,PEX5,FAM184A,RAP1GDS1,RBBP6,RFX5,RIC8B,RPRD1A,ZFHX4,ROBO1,LRRK2,NCBP3,FAM19A1,SCG5,SH3GL2,FBXO11,BCAN,ST8SIA1,PAAF1,KANSL3,SLC6A8,KDM4D,SLC8A3,SLC9A5,SLC22A4,TET1,NAXD,SORCS3,SMARCD3,TTC17,INAVA,RIMS1,SNAP25,MAPKBP1,HECW1,MCF2L2,POGZ,SS18,NSFL1C,ARHGEF9,SYN2,SYT4,TACR1,KLHL4,ANO4,DMXL2,ZEB1,WDR7,SLC19A3,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,AHCYL2,TGFBR3,HHIP,ANKRD24,SEZ6L,ZNF346,SMUG1,MKRN3,MAP3K12,FAM47E,EPM2A,UBE3B,KAT6A,SMIM8,SLC39A12,SLC4A10" MicroRNA hsa-miR-4318:mirSVR_highEffct hsa-miR-4318:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.64E-74 5.42E-70 4.22E-73 3.89E-72 176 682 "CLK4,AS3MT,ARID1A,GPRIN1,XKR4,NLGN4X,CASKIN1,HACE1,TAOK1,FGD2,LCORL,PPFIA1,CACHD1,API5,SHTN1,ZNF582,ADAM23,RGS9,ST3GAL5,OSGIN2,IL33,CANX,CLDN10,AIFM1,CDC27,B4GALT6,PPT2,NRXN1,CCDC151,FHL5,CNR1,CNTFR,CREM,CRMP1,CTH,ARHGAP32,GAPVD1,DCAF8,PABPC5,ARMCX4,PITPNC1,CEP170,CPEB2,DMTF1,DTNA,EDNRB,KLHL5,OPTN,SUGP2,PLEKHA1,EPB41,SRRM1,TMEM74,NRN1,STRADA,SLC9B2,FGF12,CAP2,WDR83,B3GAT1,AP4B1,GABRB3,ZNF274,DISC1,TUBA8,WASHC2A,GK,TOX3,ZNF638,NR3C1,CIT,AP4S1,MAEL,RBPJ,JAK2,KCNA2,LIMS1,HECTD2,MAP4,MEIS1,MN1,ADAM22,MYT1,NCAM1,P2RX7,P2RY1,PCDH8,PCDH9,PDGFRA,GPR85,BEST3,PIK3R1,PPARA,MED1,CEP41,MAPK7,HYDIN,RELN,SNRK,WDR25,PLPPR1,RAB3A,RAD51D,ENOX1,REV3L,ERI2,RFX4,DCUN1D2,CARF,ELP2,RPL15,ARMH4,UEVLD,ACER3,ATAT1,SCN2A,SCN3A,FAM19A1,TRIM46,ITSN1,MAGI3,SEC31A,SLA,NBPF1,RUFY2,SLC6A1,SLC12A2,ATF7IP,ZKSCAN3,CDK5RAP2,MYH15,SNAP25,MBD5,MYO16,UNC80,KDM4C,KIF1B,SAMSN1,SMOC1,ZC4H2,STAU1,ARHGEF9,SYT1,ANKRD12,MTCL1,CAMSAP2,FAM208A,ANO4,VWC2,ZFP90,ZEB1,TRIM2,USP32P1,GPRIN3,FRYL,SIK3,CYB561A3,AP4E1,TGFBR3,ASXL3,TMOD1,CSMD1,TPM3,SSBP2,UBE3A,ZIC1,ZNF19,AGMO,ANKS1B,CADM2,STOX2,PRDM10,PAK5,CERS6,TRAM2-AS1,RNF170" MicroRNA hsa-miR-124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.53E-73 8.58E-70 6.68E-73 6.15E-72 262 1446 "SDE2,FMNL2,DSCAML1,ADCY6,ADD3,ESYT2,OSBPL8,CC2D2A,AK2,HFM1,UNC79,C6orf89,MYH7B,EPB41L5,LGR5,CDC14B,TMEM263,PLA2G4C,CAPRIN2,CCAR2,DDX3Y,ADAM15,HCN2,DCAF5,LDLRAD4,CA12,CABP7,CAST,INA,CD86,ARHGEF1,CDC27,CDH2,CDO1,IGFN1,CRLF1,PLEKHB1,LSMEM2,ARHGAP22,LHX2,TPP1,CLTA,TJP2,QKI,TMEM184B,CNN3,IQCK,CABP1,FAM171B,CLOCK,GDA,LRIG1,MICAL2,IPCEF1,CTNND1,ECE2,RIPOR2,PHF19,KIF26A,RASSF2,MAML1,DAPK1,AIF1L,GIT2,DBT,DCC,ARMCX2,BLOC1S6,G3BP2,CCDC3,CHRDL1,CDON,DNM2,RCAN1,GOLT1B,E2F5,E2F6,EDN1,PHC2,HIPK3,FCF1,GOLGA7,PLEKHA1,EML1,CALCRL,MFSD10,STX2,ERBB2,ZNF549,GMPR2,F3,TUBB4A,RACK1,FECH,FGF1,FGFR1,MAD2L2,FOXF2,ZBED3,ADGRA1,ARPP21,NEK6,DISC1,SEPT9,ARFIP1,LYVE1,SPIN1,GPM6B,GRIA1,GRIA2,RFFL,NR3C1,GRM1,GSN,FAM19A2,KAT7,BVES,ATOH8,IRAK3,FRMD3,ATXN2L,ELOVL5,IFI16,IGFBP1,RBPJ,IL6R,ZNF678,TUBB2B,SLC35G1,KCNK1,KCNK2,L1CAM,LAMP2,ASPRV1,MBNL1,CHST6,SHC3,MIA2,POC1B,MKLN1,AFDN,MOBP,MOV10,DBNL,COMMD5,MSRA,MYCN,NASP,NBL1,NCF2,NFIA,NFIX,NME4,PAK3,PBX1,PDE3B,PIK3C2A,ZNF655,RETREG1,PLEC,SMOX,PRRX1,PPARA,MINDY2,PRKCB,EPDR1,PRPH,CNNM2,LAMA1,TMEM104,SPDL1,PTPRB,PTPRZ1,RAB3IL1,USP47,ZDHHC14,DPF2,MORC4,RFX2,RGS4,KIF7,SLC25A36,RAVER2,ROM1,ELP2,CCDC102B,SPIN3,RYR3,TMEM156,FOXRED2,SCN3A,CASC3,NLGN4Y,SGK1,KIF16B,SHMT2,HKDC1,DZIP1,SLC1A3,RAB3GAP1,LIMCH1,KIF13A,PALLD,ZCCHC24,ZHX3,UNC5B,BEX1,KIF1B,TROVE2,ITPRID2,SAMSN1,LRRC4,MPRIP,KANK1,SYPL1,MTCL1,ROBO3,CAMTA1,DNMBP,UNC5D,IQCE,NEU4,KIAA0930,CUX2,TPCN2,SYNE1,SIRT1,TMEM121,CRB1,GPR161,SLC44A1,ICAM5,TPD52L2,TPM1,C9orf85,PDSS1,TRPC1,TRPS1,TSN,TUB,TMEFF2,MTCH1,MICAL1,WIPF1,PORCN,CLDND1,ETNPPL,ANKS1B,FTSJ1,SYNC,DHX33,ZXDA,EVI5,LMAN2L,TUBA1A,PLSCR4,MSRB3,TTC7A,FXR1,FRMD6,GAN,LAS1L" MicroRNA hsa-miR-215:mirSVR_lowEffct hsa-miR-215:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-73 8.86E-70 6.89E-73 6.35E-72 209 955 "SDE2,ABHD6,NBAT1,KLHL32,GALNT16,TMCC3,PWWP2A,HACE1,AMPD3,PPP4R4,ASPH,ATP1A2,N4BP2L1,NOL4,DPY19L3,DOCK11,SNAI3-AS1,DNAJC27-AS1,ST3GAL5,SYNJ2,GYG2,CACNA1I,LURAP1,PTBP2,SYT6,INA,AIFM1,DLGAP1,NOG,SOCS6,CHN2,FBXO7,RCHY1,SMARCAL1,SEC31B,ANKRD44,TRIM69,MICAL2,IPCEF1,VCAN,APPL1,CTH,GREB1,NOS1AP,ARHGAP24,DCAF8,IST1,DNAL1,JAKMIP2,C8orf34,ZBTB24,COPS7A,BLOC1S6,FBXO25,RHOBTB1,DLG3,CDON,CASP8AP2,DPYSL2,DYRK1A,KRBA2,ANKRD46,TMTC1,YAF2,ABI2,MRVI1,REEP2,EFEMP1,CEP78,TOMM40L,STRADA,FER,FGFR1,FOXG1,FLNC,FLT1,EFCAB2,APOPT1,ARFGAP2,STAU2,B3GAT1,SARAF,OGA,ZMAT1,MEGF10,GABRA1,GABRA2,ZMYND11,IP6K3,DISC1,ATP8A2,MALT1,SPIN1,GLYR1,GNG3,EML4,GRIA1,WIF1,RASSF8,HRH3,ARHGAP19,ARHGAP36,CPT1C,SHISA6,SMAP1,IGF1,GAREM2,IL6ST,KCNA1,KCNA2,KCNJ5,KCNK3,CREG2,CYP27C1,TTYH2,MAN2A2,SYT9,MEF2C,MEIS1,THYN1,MYO6,MYO9A,RTL5,NCAM1,ZC3H12B,NEFM,NOVA1,SLC11A2,OPA1,OPHN1,CNTN3,SLC10A4,CAMKV,RETREG1,PURG,PMP2,RETREG2,TATDN3,PPP2R2C,PRKACB,LRRC49,SYTL2,STK32A,ZSCAN32,PTPRE,TTC13,GTDC1,SLC25A36,RNASEL,ZFHX4,CCDC25,CCDC102B,RPE,GLDN,LRRK2,SATB1,SCAF8,ASAP3,NUBPL,PEX26,NAPB,SLC15A2,ATF7IP,SLN,ZNF667,SMARCA4,INAVA,SNRPN,SP4,NMNAT2,ENKUR,MYCBP2,KDM4C,KIF1B,RBM26,SPART,TAB2,LARP4,NECAB1,FGD4,MTCL1,CAMTA1,TAL1,TCF7,NSD1,CRB1,RGMB,SYNPO2,METTL3,TUB,RPL7L1,CLEC2L,AMOT,USP1,BEST1,RICTOR,ZNF708,ZNF24,GPR158-AS1,ZBTB38,ANKS1B,CA10,EMSY,PDSS2,PAK5,HNRNPA3,PHTF2,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-192:mirSVR_lowEffct hsa-miR-192:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.58E-73 8.86E-70 6.89E-73 6.35E-72 209 955 "SDE2,ABHD6,NBAT1,KLHL32,GALNT16,TMCC3,PWWP2A,HACE1,AMPD3,PPP4R4,ASPH,ATP1A2,N4BP2L1,NOL4,DPY19L3,DOCK11,SNAI3-AS1,DNAJC27-AS1,ST3GAL5,SYNJ2,GYG2,CACNA1I,LURAP1,PTBP2,SYT6,INA,AIFM1,DLGAP1,NOG,SOCS6,CHN2,FBXO7,RCHY1,SMARCAL1,SEC31B,ANKRD44,TRIM69,MICAL2,IPCEF1,VCAN,APPL1,CTH,GREB1,NOS1AP,ARHGAP24,DCAF8,IST1,DNAL1,JAKMIP2,C8orf34,ZBTB24,COPS7A,BLOC1S6,FBXO25,RHOBTB1,DLG3,CDON,CASP8AP2,DPYSL2,DYRK1A,KRBA2,ANKRD46,TMTC1,YAF2,ABI2,MRVI1,REEP2,EFEMP1,CEP78,TOMM40L,STRADA,FER,FGFR1,FOXG1,FLNC,FLT1,EFCAB2,APOPT1,ARFGAP2,STAU2,B3GAT1,SARAF,OGA,ZMAT1,MEGF10,GABRA1,GABRA2,ZMYND11,IP6K3,DISC1,ATP8A2,MALT1,SPIN1,GLYR1,GNG3,EML4,GRIA1,WIF1,RASSF8,HRH3,ARHGAP19,ARHGAP36,CPT1C,SHISA6,SMAP1,IGF1,GAREM2,IL6ST,KCNA1,KCNA2,KCNJ5,KCNK3,CREG2,CYP27C1,TTYH2,MAN2A2,SYT9,MEF2C,MEIS1,THYN1,MYO6,MYO9A,RTL5,NCAM1,ZC3H12B,NEFM,NOVA1,SLC11A2,OPA1,OPHN1,CNTN3,SLC10A4,CAMKV,RETREG1,PURG,PMP2,RETREG2,TATDN3,PPP2R2C,PRKACB,LRRC49,SYTL2,STK32A,ZSCAN32,PTPRE,TTC13,GTDC1,SLC25A36,RNASEL,ZFHX4,CCDC25,CCDC102B,RPE,GLDN,LRRK2,SATB1,SCAF8,ASAP3,NUBPL,PEX26,NAPB,SLC15A2,ATF7IP,SLN,ZNF667,SMARCA4,INAVA,SNRPN,SP4,NMNAT2,ENKUR,MYCBP2,KDM4C,KIF1B,RBM26,SPART,TAB2,LARP4,NECAB1,FGD4,MTCL1,CAMTA1,TAL1,TCF7,NSD1,CRB1,RGMB,SYNPO2,METTL3,TUB,RPL7L1,CLEC2L,AMOT,USP1,BEST1,RICTOR,ZNF708,ZNF24,GPR158-AS1,ZBTB38,ANKS1B,CA10,EMSY,PDSS2,PAK5,HNRNPA3,PHTF2,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-296-5p:mirSVR_lowEffct hsa-miR-296-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.83E-73 1.03E-69 8.00E-73 7.37E-72 216 1017 "SERPINA3,DGCR6,ASPHD1,SYN3,ACTN1,PLEKHG5,ADD2,UNC5A,KIAA1211,ADRA1D,SNX32,DISP3,TAOK1,LTBP4,BIN1,APBB1,PHYHD1,PPFIA3,SPTBN4,ASGR1,ATP2B3,B3GALT2,TTLL9,ADGRB2,LINC00847,KSR1,BMP7,GPC2,CACNA1E,CACNB4,DIRAS1,TRIM41,LDB2,ARHGEF1,NEURL1,ARHGEF2,LARGE1,NOG,GPR37L1,PPT2,STOML1,CLTB,TMEM184B,CNGA3,ARHGEF6,TOGARAM2,ZNF521,IGDCC3,SLC32A1,CLIP3,TRIM69,CSF1,CSNK1E,CST3,ARHGEF4,SIRPA,DBN1,SV2B,SV2A,SRGAP3,SGSM2,FAM107B,KIF19,DMPK,MED12,DPH1,FAM57B,DPYSL2,TOM1,EDNRB,HEYL,SIDT2,ELAVL3,CERCAM,HSD17B14,MFSD10,COQ7,DMTN,SEZ6,EPHB1,ANKRD13B,SPEG,DLC1,FGF11,FGFR1,FGFR3,APOPT1,HHIPL1,BRPF3,INPP5K,GCK,ALDH1L1,CYP46A1,CRCP,GLYR1,POLL,LUZP2,GNAS,GPD1,LILRA2,GRIA1,GRIN1,TMEM25,LINGO1,RNFT2,GUCY1A1,ATOH8,HRH3,ATXN2L,ELOVL5,LRRC75A,C2orf72,KNDC1,IL11RA,ITPKB,KCNA1,KCNA6,KCNK3,CLEC18A,MAP4,MATK,MMP16,MPP2,PTOV1,MTTP,NCAM1,NEUROD2,NNAT,NME4,LRIT2,NUMA1,TBC1D25,OGDH,PFKFB4,KCTD15,ST8SIA5,PLXNB3,MBOAT7,POLR2F,TMEM235,PTPA,GRAMD1C,MASP1,WDR25,NKAIN1,RAB3A,RAD51D,RASGRF1,ZDHHC4,RGS3,ARHGEF10L,MYH14,ARMC5,EPHA10,ACER3,MEG3,HSD11B1L,SCN2B,HES6,ZNF821,GALNT10,MRAS,SLC1A7,SLC2A5,SMTN,SLC6A8,SLC6A9,SCMH1,OGDHL,IGSF9B,MAPKBP1,WDTC1,KIF21B,ZSWIM8,TSPYL2,C11orf87,ITPRID2,SSPO,MPRIP,SEPT8,AJAP1,SYT11,SUPT5H,ARHGEF9,C3orf70,COBL,TACR1,TAL1,SMG6,WSCD1,USP22,HIF3A,TGFBR3,SLC44A1,ZFP91,KCTD2,PIK3R5,TPM2,WBP2,PRMT8,TRO,TRPM2,MGAT5B,MTCH1,LAT2,NSD2,CFAP298,ZNF213,SLC30A3,PRDM2,RGMA,PARP6,ITM2C,PCBP4,ADAMTS10,LAS1L" MicroRNA hsa-miR-181a-2*:mirSVR_highEffct hsa-miR-181a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.53E-73 1.42E-69 1.11E-72 1.02E-71 187 773 "RALGAPA1,CLK4,NCKAP5,CSMD3,PWWP2A,RNF150,GPR158,KCTD16,HACE1,LRRC7,GOLGA7B,BCAS1,ATM,ATP1A3,ALDH7A1,ADAM23,ADGRB3,MPDZ,RGS9,NRP2,BTK,OSGIN2,KALRN,SLC25A14,CAPN3,SYT6,VSTM2A,TMEM257,ARHGEF2,REPS2,CDH8,LGI1,LOC730101,CFL2,SRSF11,TJP2,C4orf33,NIPBL,AKAP6,IGDCC3,ANKRD44,NCOR1,SNCAIP,FEZ1,CSNK1G3,SUSD5,PDE4DIP,EDRF1,NOS1AP,CYBB,KIAA0513,ZFYVE16,ARMCX4,ZNF804A,MAGI2,DDX46,NTM,DMD,NR1D2,DPP6,EDNRB,EGFR,KMT5B,COQ7,TAOK3,FGF11,CAP2,ST6GALNAC3,SARAF,ZMYND11,GALC,DISC1,MYOZ2,GPR75,TNRC6A,MSL3,ZNF638,GNG4,GPR12,GRIA1,GRIA2,ADAMTS8,NR3C1,KAT7,PTGDR2,HMGCL,AGBL5,ZDHHC15,HTR5A,MSL1,NKD1,IL6R,IL11RA,NME9,ITGA7,ITPKB,SLC35G1,KCNC1,HECTD2,SMAD9,MBNL1,SYT9,MDM4,NRBP2,THYN1,DDX25,MXI1,MYO9A,FXYD6,NEK1,NFE2L2,NOVA1,CHAMP1,NALCN,PIK3C2A,SNX10,ING3,POLG,TATDN3,PPP2R2C,PRKAB2,PKIA,MAPK8,GON4L,MTMR10,CEP97,TMEM255A,RAD17,ARID4A,ZYG11B,RFX2,ZDHHC4,SEC61A2,RNF220,NUDT11,CCDC82,C12orf49,CARF,SALL1,SCN2A,SCN3A,SCN8A,ELMOD1,SH3GL2,NTNG1,SHC4,SLITRK3,ST3GAL3,ZNF365,SLC9A5,SLC11A1,SPHKAP,GKAP1,RCOR3,SNRPN,MYO16,TRERF1,BDP1,KDM4C,C11orf87,SRPK2,SSTR2,NKAIN2,NXT2,FGD4,SYT1,TBCEL,DOCK9,USP32P1,CCDC173,AKTIP,SYNPO2,FAM155A,UBTF,WIPF1,GUSBP1,ZFP37,SPIRE1,WNK1,SLC30A4,EPM2A,KAT6A,ADAMTSL3,ZNF248,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-627:mirSVR_highEffct hsa-miR-627:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.62E-73 1.47E-69 1.14E-72 1.05E-71 203 906 "ABHD6,DSCAML1,SLITRK1,GALNT13,PLEKHH1,INTS2,SPARCL1,ALCAM,ABCD2,AMT,EP400,SUGT1P4-STRA6LP-CCDC180,APBA2,CACHD1,API5,PPP4R4,SLC2A11,MTMR9,ADAM23,SCAPER,KALRN,SPAG9,NFS1,CBR1,ZNF501,CLDN10,CERS5,AIFM1,CD38,CDC27,CHGA,CASC2,TAOK2,RAB33A,AKAP7,BTF3L4,LETMD1,AKAP5,SLC4A8,BAG4,TOGARAM2,ENTPD4,HAPLN1,HINFP,CS,NCAN,PHF14,CTNND1,FRMPD4,TBC1D5,C8orf34,SGSM2,CCDC3,DLG2,NYAP1,DNAJB6,GOLT1B,FAM135B,HIPK3,SEMA3D,KLHL5,FSD1L,RBM12,EFNB3,EGFR,RGS17,EN2,EPB41,EPHB1,DENND4A,SRARP,CDKL3,ST3GAL6,ZSCAN30,SPSB4,SEC23B,SLC37A3,ZCCHC17,SDCBP2,GABRA1,GABRA2,B4GALNT1,JPH4,ERAP1,MTHFD2,ATP8A2,GART,TNRC6A,MSL3,DCLK2,PCLO,MFSD2A,SOX21,PSIP1,PADI2,TNFAIP8L3,HNRNPK,EID2B,ZIC5,C2CD4C,KCNA1,KCNB1,KIT,CYP27C1,INSYN2,LIMS1,ASPRV1,MAN2A2,MARK1,MAT2A,AQP11,EFHB,COL28A1,NCAM2,NDUFA5,NELL1,NFYA,NOVA1,DNHD1,LRIT2,PAH,CNTN3,PDCD2,GDAP1L1,PIK3C2A,ZNF655,RC3H2,SEPT4,SH3KBP1,CRLS1,PPP3CB,KANSL1,RASGEF1B,GDPD2,MDGA2,CNTLN,PTHLH,EML5,PTPRE,SH3TC2,FAT4,RAP1GDS1,VEPH1,KLHL11,SETD5,GSTCD,ROM1,NEK11,RPL15,LINC00461,SEC14L1,ITSN1,SHMT2,CNKSR2,SLA,PPP4R3A,BTBD3,SMARCE1,SNAP25,SNRPN,TAB2,SEPT3,KLHL7,FGD4,SYN2,POPDC3,TAL1,VWA3A,EHBP1,WDR7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,HHIP,DDHD1,BHLHB9,ERCC6L2,C5orf64,TPM3,RGMB,ZMYND8,TMPRSS5,TSC1,RPL7L1,EIF4ENIF1,AMOT,OSBP2,ZNF781,CLDND1,TRIM9,GPR158-AS1,MKRN3,FIP1L1,FAM13C,MARCH8,PHTF2,JMJD1C,RNF146" MicroRNA hsa-miR-192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-73 1.98E-69 1.53E-72 1.41E-71 213 994 "CLK4,AS3MT,CDC7,KIDINS220,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PHF12,PKP4,APC,IGDCC4,TMEFF1,ZFYVE28,ASPH,ZBTB10,MTMR9,BARD1,BLM,DST,FUBP1,NIPA1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,RCBTB2,CHM,B4GALT6,FAM189A2,TJP2,ABCG2,DNAJB5,AKAP7,BTF3L4,FAM171B,PNKD,LRIG1,ARHGEF10,ATRNL1,APPL1,CTH,EDRF1,PHF19,DNAL1,DBT,PITPNC1,COPS7A,BLOC1S6,FBXO25,KBTBD11,CDON,DYRK1A,E2F5,PHC2,EEF1A2,IRAK4,PCOLCE2,EML1,MFSD10,EPS8,CEP85L,EXTL2,KATNAL1,CLVS1,ABCA8,CORO2B,ST3GAL6,CEP78,TMEM164,MEX3B,SEC23B,SYNCRIP,SEMA4D,SMC2,KHDRBS3,SARAF,ZMYND11,KIAA1841,GATM,FAXC,KIAA1958,KCNMB4,RAB40B,PSRC1,GPR19,GPR37,GRIA1,CIT,FAM222A,RASSF8,ARHGAP19,ELOVL5,FAAP20,GAREM2,ZIC5,LRRCC1,USP54,IL6R,IL6ST,ZNF385B,ITGAV,SLC35G1,KLHL23,KIF5C,KPNA5,TTYH2,LIMS1,MAN2A2,MDM4,MEIS2,MXI1,SFR1,NEK1,NFYA,NUCB2,SETD4,OPA1,GPR137C,PDE2A,CDK14,ANLN,SNX10,KCTD15,GPSM2,PRIMPOL,MINDY2,EPDR1,MAPK9,VPS13C,UHRF1BP1,PTPRE,RAP1GAP,RADX,TRIM68,RET,RIC8B,RNASEL,RIMKLA,MAP6D1,CNTNAP3,RMI1,ATXN7,HES6,IL17RB,ASRGL1,ZFP30,FERMT1,ANKRD6,CLSTN1,WDR47,KDM4D,RADIL,ARHGEF40,SLC9A5,SCMH1,ZFP1,LIMCH1,FAM126B,FNBP1,SP4,EMC1,LHFPL4,SSTR2,SS18,TBL1X,TMEM136,SATB2,TCF7,RPGRIP1L,DICER1,SIRT1,RP9P,C18orf54,ZMAT3,DDHD1,TMPO,TPM4,ZNF346,STXBP4,TRPC1,TTPA,CADM1,UGT8,PITPNB,USP1,BCL2L13,CCDC14,NSD2,XPO1,ZBTB14,ZNF45,LYPD6,REEP1,ZNF184,EML6,WNK1,NT5M,LRP8,STOX2,CAB39L,EPM2A,FAM182B,PHTF2,FBXO36,CERS6,ZNF248,MSRB3,NHSL1,SPATA13" MicroRNA hsa-miR-199a-5p:mirSVR_highEffct hsa-miR-199a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.55E-73 2.55E-69 1.98E-72 1.82E-71 190 800 "RALGAPA1,KCNH8,ASPHD1,KLHL32,CCDC85A,ADD3,CDC7,PTCHD1,OGT,ANK3,MAP4K3,PHF12,APBB1,ALS2,APOC1,PPFIA3,DACT3,DDX3Y,BACH1,FUBP1,JAZF1,OSGIN2,DDR1,NFS1,CERS5,LRRFIP1,LARGE1,CCPG1,CFL2,COPB2,CHN2,CASC2,CNOT8,JAM2,PPT2,CLTC,FAM149A,CHD1L,PREPL,HAPLN1,RGS6,UBXN2A,RUBCN,CYBB,HDAC9,GPRASP1,GAPVD1,RASSF2,TBC1D5,YTHDC1,ZEB2,MYEF2,KIAA0753,MAGI2,BLOC1S6,SACS,FAM107B,ABI1,E2F6,TSPAN5,OPTN,PAN3,USPL1,SRRM1,IGSF6,RCSD1,RACK1,FDFT1,TESK2,KIAA1109,TMEM164,SEMA4D,SLC37A3,NBEA,NSG1,SARAF,GABRA2,GAD1,NCKAP1,ZNF559,NEU3,GCNT2,CSDC2,PPARGC1A,RND1,DBF4,TOX3,GLUL,GPD2,FUT10,GRIA2,GRIA4,PRDM5,FAM19A2,AGBL5,MSL1,IGFBP1,METTL21A,KCND2,GPR62,KCNH2,KCNK2,KCNMA1,KIT,INSYN2,PAXBP1,SYTL4,ARHGAP12,NCOA7,ZFYVE27,MAT2A,MBNL1,MEIS2,ERICH3,GIT1,NF1,SLC10A4,PIK3CD,PCDH18,TRHDE,FA2H,POU3F2,CRLS1,PRKAB2,SYTL2,PIGG,MTMR10,ZNF844,SUSD4,FIGN,RGS10,SEC61A2,ROBO2,RORB,ELP2,MRAP2,NEK11,KCNIP1,CLIP1,SATB1,LRRTM4,ZFP2,ASRGL1,ITSN1,NTNG1,NLGN1,BTBD7,SORCS3,RCOR3,UNC80,WDTC1,SOX2,ENKUR,ERC1,KIF1B,CLASP2,EPB41L3,LARP4,NXT2,ZSCAN29,ADHFE1,FGD4,DDHD2,CAMSAP2,ANO4,ZEB1,DNAH7,SIRT1,ZFPM2,CRB1,ERCC6L2,TMPO,RUSC1,TMPRSS5,TSC1,TST,HIRA,XRCC4,PCDH20,ZNF19,ZNF177,PCBP1-AS1,MFF,LRP8,STOX2,TMEM163,WNK3,FAM13C,PHTF2,ACTR3B" MicroRNA hsa-miR-3188:mirSVR_highEffct hsa-miR-3188:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.58E-73 2.57E-69 1.99E-72 1.84E-71 197 858 "SERPINA3,C3orf14,FMNL2,OLMALINC,SLC44A5,HECW2,AGT,AK2,TAOK1,FAM135A,KCNT1,ANK2,EP400,APLP1,GPAM,IGDCC4,SPTBN4,ATP2A2,BACH1,KSR1,DST,ARHGEF7,GYG2,SGCE,CACNB4,THSD7A,PTBP2,SLC25A14,RUNX1T1,LDB2,MTMR7,INA,CDC42,ZMYM4,TIGD7,CLCN3,HECTD1,SLC4A7,MAGED1,ABI3BP,GDA,CLIP3,SNCAIP,MICAL2,OSBPL3,NRSN1,BOC,HDAC9,DCAF8,DCT,C8orf34,MYEF2,COPS7A,MAGI2,NR1D2,CPEB2,MAMLD1,RBM12,EPHA5,STX2,EPS8,MRVI1,F8,CLVS1,ABCA8,FAM198B,GORAB,BAIAP2,FOXF2,SEMA4D,EFCAB2,KHDRBS3,ST6GALNAC3,STAU2,NRG3,ZNF512,PHYHIPL,CAB39,B4GALNT1,BRD8,CRCP,TNRC6A,TDRKH,CCDC184,GRIA2,GRIA4,GRIN2D,COQ10A,AGBL5,TLX1,OPALIN,SHISA6,ICA1,KCND1,KCNF1,KTN1,PAXBP1,MAP4,AQP11,MEIS1,PPM1L,MITF,CD200,SCG3,CTNNA3,MYO7A,NELL2,NF1,NTRK3,NUMA1,PAK3,PDE4B,PDGFRA,ENPP2,GNG2,BEST3,GDAP1L1,ANLN,JAKMIP1,SLC36A4,PTPA,HYDIN,SYTL2,MDGA2,BDNF-AS,STK32A,PEX5,NWD1,ARID4A,RADX,ZDHHC14,SLC6A15,UBR7,SLC25A36,ZNF532,TMLHE,LRRK2,ABCA11P,CLIP1,FAM192A,SCN2A,ELMOD1,ZFP30,ITSN1,CPEB3,ST3GAL3,SLA,WDR47,ZNF430,SORCS3,SMARCE1,RCOR3,CABCOCO1,SNRPN,HECW1,KIF1B,ATP10B,NKAIN2,ERBIN,TTBK2,ADHFE1,ADAMTS17,TMEM150C,MTCL1,KLHL4,TCEA1,SYNE1,ARHGEF12,GPRIN3,TEX15,RNF216P1,TF,SIRT1,ZMAT3,SLC44A1,NR2E1,FAM124A,R3HDM1,NPL,TRIO,PPIL6,ZNF610,RPL7L1,OSBP2,TOM1L2,RICTOR,ZFP37,TRIM9,EML6,CA10,SLC38A1,NAV3,PDSS2,DOCK8,PAK5,PHTF2,SENP7" MicroRNA hsa-miR-660:mirSVR_highEffct hsa-miR-660:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.10E-73 2.87E-69 2.22E-72 2.04E-71 186 768 "ABAT,RNF150,ZNF608,RTL9,OSBPL8,TAOK1,LRRC7,UNC79,DPP10,USP28,PPFIA2,PKP4,GPAM,APP,MIER1,ASPH,CCAR2,SLC2A11,DST,OSGIN2,IL33,CALB2,CAMK2D,CAPN3,SPAG9,CLDN10,CCNH,AIFM1,MAGI1,DLGAP1,CLGN,SRSF11,MS4A7,NDST3,ZFYVE9,KIAA1549L,CNGA3,GDA,SUSD5,PDE4DIP,CCDC144A,TOX,KIAA0513,DGKB,GIT2,ZNF804A,HP1BP3,DDX46,ALKBH8,NTM,G3BP2,DPP6,DTNA,MAMLD1,DYRK1A,ABCC9,RBM12,PHF20L1,AASS,IRAK4,VPS13B,KCNMB2,ANKRD13B,SPEG,ETV1,GORAB,KIAA1109,FOLH1,NBEA,NPTN,ARFGAP2,MSANTD4,MPP6,ZNF512,MEGF10,JPH4,ERAP1,MTHFD2,DISC1,ALDH1L1,GGT7,PPARGC1A,GLS,GNAS,FUT10,CECR2,ATP2B1-AS1,GRM1,CIT,FAM19A2,CELF3,ZHX1,ARHGAP36,MIER3,FAAP20,EID2B,DOCK7,ZNF385B,INSYN2,LIMS1,LDLRAD3,SCG3,NAP1L1,NEK1,NF1,NRCAM,ODF2,OPA1,OPHN1,PCDH9,PCSK2,PFKFB2,DUSP26,A2ML1,PLCL1,MAPKAP1,PPP2R2B,PPP3CB,HYDIN,SIDT1,MDGA2,CNTLN,PTPRG,RAP1GDS1,RBBP6,SLC6A15,ZMAT4,RFX3,ZNF532,YY1AP1,STK32B,MEG3,SEMA6D,SCN2A,SCN3A,LRRTM4,SCP2,SFPQ,ITSN1,FERMT1,NTNG1,MAGI3,CHD9,FBXO11,SLITRK3,CNKSR2,ABLIM3,SLC8A1,MYH15,LIMCH1,SON,NPAS3,SPART,PBLD,SMOC1,NKAIN2,KLHL7,VPS13A,PLCB1,TAF9,CAMSAP2,TCF4,SATB2,ZFP90,HIF3A,ZFPM2,C18orf54,TPD52L2,AMACR,TRPC3,TSC1,GORASP1,ZBTB14,ZIC3,ZNF184,WNK1,LRP8,LINC02210,TMEM163,WNK3,MVB12B,RGS7BP,AMN1,PAK5,CBLN2,SENP7" MicroRNA hsa-miR-218-2*:mirSVR_highEffct hsa-miR-218-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.67E-73 3.19E-69 2.46E-72 2.27E-71 190 801 "KCNH8,NDRG3,ADCY6,KLHL13,RTL9,ALAD,AMPD2,LRCH2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,CACHD1,BRINP2,CADM3,DPY19L3,BACH1,DST,OSGIN2,CACNA1E,PTBP2,CAST,CERS5,CDC27,CDH8,CHGB,CHN2,NRXN3,CLU,MAP4K4,ARMC8,COL4A5,ZFP28,CREM,NCOR1,GDA,SNCAIP,LRRC3B,VCAN,APPL1,MATR3,DGKB,ARMCX2,ZEB2,KIAA0753,ZC3H11A,POM121,DNAH9,FAM78B,DNM1L,EDIL3,SGK2,RBM12,APH1A,KMT5B,MRNIP,RCAN2,KCNMB2,RABEPK,ARMCX1,WAC,FABP7,ACSL4,ST3GAL6,CEP78,GTF2IRD2,FGF1,FGF11,FGF12,MEX3B,ATP6V1H,ZNF605,FYB1,PHYHIPL,ZNF559,DNER,RND1,DCLK2,GPD2,GRM7,HSF2,HTR2A,EID2B,DOCK7,IL6ST,ZNF678,SLC35G1,KCND2,KIF2A,IPO5,HECTD2,PIK3AP1,MDM4,MEIS2,SCAMP5,TCEAL5,P2RY13,NCF2,NF1,IGSF11,OGG1,PAH,GNG2,OLA1,ZNF655,A2ML1,KCTD15,EXOSC10,NXPH1,DRAM2,PPP3CB,GRAMD1C,HYDIN,DCHS2,CNTLN,ANKHD1,PTK2,TMEM260,TTC13,SUSD4,RDX,SLC6A15,RNASEL,SETD5,RORB,NEK11,ACER3,TCP11L1,ZNF354C,TMEM156,SAFB,LINC00461,GALNT10,SH3BGR,SHC4,SEC31A,RUFY2,MTERF2,ELMO2,SLC20A2,SPHKAP,ANKRD36,KIF13A,DOP1A,WDTC1,MYCBP2,TAB2,ZC4H2,MPRIP,STAU1,KANK1,FAM168A,PRRC2C,SYPL1,SYT4,C12orf76,EHBP1,ZEB1,RPGRIP1L,SYNE1,SLC19A3,AKNA,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SPX,TPM3,RGMB,CA14,TTC3,CADM1,FLRT2,ZNF709,BEST1,ZFP37,ZIC3,ZNF138,FSTL5,DHX33,STMN4,PRDM10,HPS4,CAB39L,PDSS2,RNF170,IFT88" MicroRNA hsa-miR-338-3p:mirSVR_highEffct hsa-miR-338-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.69E-73 3.20E-69 2.47E-72 2.27E-71 194 834 "ACADM,TMCC3,ERMN,PWWP2A,KIAA1211,ESYT2,ZNF608,MTUS1,LRRC7,MAP4K3,LRRC4C,TMEM263,MARCH3,MARK4,ZBTB10,ATP2B1,ZNF582,NOL4,DCAF5,BLM,CFLAR,BMP7,SYNJ1,JAZF1,C5,CACNB2,THSD7A,CAPN3,DGKI,LRRFIP1,MAGI1,CDR1,CLCN3,LY86,LETMD1,SLC4A8,CP,SEC31B,AKAP12,ANKRD44,UBXN2A,HDAC9,DGKB,JAKMIP2,C8orf34,MYEF2,SRGAP3,G3BP2,WDR20,KIF19,ABI1,DTNA,DNAJB6,FAM135B,PHF20L1,ABI2,COPS4,PLEKHA1,F8,EFEMP1,ZNF589,ATP13A4,FLT1,UFM1,PRELID3A,SDCBP2,CHL1,GALNT15,ZNF559,TUBGCP4,TOX3,DCLK2,GNAS,GPD2,LILRA2,EML4,GRIA2,GRIA4,NR3C1,LINC00839,ZBTB49,FRMD3,NCKAP1L,HMGB1,HNF4G,ZNF678,DIPK1A,LRRTM3,SLC35G1,KCND2,CREG2,STXBP5,SYTL4,NCOA7,MBD1,MBNL1,TM6SF1,SRSF12,CD200,ERICH3,BLOC1S2,ZNF862,NAP1L1,NDP,IDNK,NEUROD1,SLCO1C1,CNOT4,NOVA1,HCN1,SNTG1,C11orf49,SCHIP1,SEPT4,PPM1B,TATDN3,APTX,GDPD2,PTCH1,PTN,PTPRG,ACSM5,QDPR,RAD51D,ZNF493,RDX,ZYG11B,RFX4,RGS7,ARHGEF10L,SEC61A2,ZFHX4,CARF,ELP2,EPHA10,FBXW7,ATP8B4,RTN1,ATXN7,LRRTM4,FNIP1,ZFP2,SH3GL3,CPEB3,SLITRK3,PREX2,SMTN,SLC12A4,ARFGAP1,MYH15,LIMCH1,RIMS1,MBD5,MYT1L,SP4,LMO3,CLASP2,TROVE2,LARP4,NEK4,SEPT8,ADHFE1,PRRC2C,VPS13A,SYN2,COBL,MTCL1,TAF9,PCDHGA11,GPRIN3,C18orf54,SLC44A1,ERCC6L2,CSMD1,C5orf64,SEZ6L,TPM1,RUNDC3B,AMACR,MEAF6,WIPF1,ZNF70,FTSJ1,EMSY,CADM2,HPS4,NELFE,RGS7BP,FZD3,CASC15,NHSL1,CBLN2,ZNF30,CPNE4" MicroRNA hsa-miR-200a*:mirSVR_highEffct hsa-miR-200a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.12E-73 3.44E-69 2.65E-72 2.44E-71 196 851 "XKR4,BRAP,KLHL13,KCTD16,NME5,ADGRF5,OGT,MAP4K3,APP,SHTN1,SLC2A11,BMPR1B,DST,ST3GAL5,SYNJ2,KALRN,RUNX1T1,CCK,TMEM257,LGI1,ZBED5,CNOT8,TPP1,QKI,CNR1,BTF3L4,ABI3BP,RCHY1,FAM171B,PREPL,HAPLN1,SEC24C,IPCEF1,SLITRK5,PITPNM3,PHF14,CTH,NRSN1,EDRF1,TCAF1,ZFYVE16,BRINP1,ARMCX4,PITPNC1,C8orf34,ZEB2,TIAM2,GSDME,DDX46,DPP6,DYRK1A,ABCC9,E2F6,EDNRA,FRY,EPHA5,GPHN,STX2,CEP85L,TMEM74,DNAJC27,F5,CLVS1,DLC1,MED12L,FGF13,MEX3B,ARFGAP2,ATP6V1H,ERGIC3,NSG2,ST6GALNAC3,STAG2,GABRA2,CHL1,BRPF3,ARPP21,GAP43,DISC1,IGSF5,SULT1C4,MSTN,ARFIP1,COPS8,GLS,GLUL,KDM2B,INSM2,PRUNE2,ATP2B1-AS1,GRIA4,WIF1,C1orf94,ZHX1,MIER3,HMGB1,SHISA6,EID2B,RBPJ,LRRTM3,KCND2,KCNJ16,CREG2,KLRC2,STMN1,VWA5A,HECTD2,PIK3AP1,MAP4,MARK1,MBD1,MBNL1,MEIS2,MOBP,ZNF680,MSR1,ZNF92,NCF2,NEK1,NOVA1,SMIM11A,HCN1,ETFRF1,PDE3A,GPR85,GNG2,PIK3C2A,ING3,CRLS1,TMEM260,ZSCAN32,PEX2,RAD51D,ZNF493,MORC4,SLC25A36,NUDT11,CARF,GSTCD,PCMTD2,CCDC102B,RPE,ABCA11P,ST6GALNAC6,WLS,CSRNP3,SCN2B,SGK1,SH3GL3,RUFY2,ZNF430,SLC14A1,BTBD7,SPHKAP,SLC22A4,SMARCE1,LIMCH1,SNRPN,ENKUR,GLT8D1,KDM4C,BEX1,KIF1B,NPAS3,SSTR2,ZSCAN29,NEK4,FGD4,ARC,DDHD2,TCEA1,USP22,PCDHB6,DICER1,ZFPM2,BHLHB9,TMPO,RFTN2,TUBB2A,EIF4ENIF1,UBE3A,PITPNB,MTCH1,NSD2,WRN,CLDND1,ZNF708,KCNT2,ZNF138,ANKS1B,PRDM10,FZD3,HNRNPA3,PHTF2,FRMD6,GAN" MicroRNA hsa-miR-452:PITA hsa-miR-452:PITA_TOP PITA 6.83E-73 3.84E-69 2.96E-72 2.72E-71 143 451 "CSMD3,ADD3,NLGN4X,FAM135A,ZNF687,MIER1,ATP2B1,SYNJ1,FUBP1,JAZF1,CAMK2G,CANX,CLDN10,CDH2,CACNA2D2,FOXN3,CHN1,QKI,ARHGEF6,BTF3L4,CLIP3,SIPA1L1,ERC2,DOCK4,HDAC4,MATR3,HP1BP3,G3BP2,GRIN3A,CPEB2,DPYSL2,ABI1,PDCD6IP,DUSP9,DYRK1A,RASGRP1,RBM12,KMT5B,ELAVL2,PLEKHA1,PAN3,DCTN4,EPB41L1,EPHA5,EPS8,ERBB4,ZIC4,HPCAL4,PHYHIPL,CAB39,BRPF3,SALL3,GAP43,GFRA1,PCDH17,TOX3,GPM6A,TDRKH,GPR22,GRM3,ADAMTS6,MAEL,FRMD3,KLF12,MIER3,ELOVL5,AGFG1,IGF1,C5orf24,KCNK2,KIT,LIFR,NCOA7,LDLRAD3,MEF2C,MEIS1,AFF1,CNTN3,PCSK1,PDE4D,SERPINI1,C11orf49,STRN3,FAT3,MED1,PPP2R5C,PKN2,RELN,SNRK,TMEM255A,ZYG11B,REV3L,PBRM1,ZNF532,RAVER2,ROBO2,KCNIP1,SEMA6D,TRA2B,NLGN4Y,FBXO11,FNDC3A,SLC8A3,BTBD7,CPEB4,SMARCA4,SNAP25,MBD5,TMCC1,PDZRN3,SON,MYT1L,SOX11,SP4,NKAIN2,SS18,ERBIN,PLCB1,SYPL1,SYT1,MTCL1,MGRN1,TCF4,CUX2,DOCK9,HHIP,RIMBP2,TP53BP2,UBE3A,FLRT2,NSD2,ZIC3,FMN2,LYPD6,ZBTB38,CADM2,NAV3,SLC17A6,HNRNPA3,ACTR3B,MSRB3,ST8SIA2,SLC4A10" MicroRNA hsa-miR-642:mirSVR_highEffct hsa-miR-642:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-72 5.74E-69 4.42E-72 4.07E-71 211 982 "ASIC2,SYS1,XKR4,CSMD3,RNF150,PCDH19,RTL9,PCDH10,PHF12,SUGT1P4-STRA6LP-CCDC180,DGKZ,UPRT,BCAS1,RGS20,PLA2G4C,ASPH,ATM,ATP6V0A1,ADGRB3,NRP2,PROM1,DST,CASTOR3,MMD2,CACNA1E,KALRN,INA,CDH2,CDH8,SYNPR,PPT2,CLCN3,TJP2,MAP4K4,MFSD4A,CP,ENTPD4,GDA,SNCAIP,LRIG1,SUSD5,FAM169A,GREB1,RUBCN,BOC,MYADM,GAPVD1,ARHGAP24,TBC1D5,KCTD8,DGKB,TMEM170A,SPOCK2,YTHDC1,JAKMIP2,ZEB2,ALKBH8,GRIN3A,PDCD6IP,GOLT1B,E2F5,FAM135B,EPB41,EPHB1,ANKRD13B,NCALD,ETV1,RTN3,NRN1,RACK1,FCGR1A,KIAA1109,CAP2,SEMA6C,ANKFY1,COQ5,SORBS1,SMC2,UFM1,GABRB1,GAD1,DISC1,WASF3,SRCAP,SULT1C4,PPARGC1A,RND1,HPGDS,RAB30,MSL3,PCDH11X,LILRA1,STMN2,TMEM25,RNFT2,UBE2QL1,MIER3,VSIG4,HMGCL,AGBL5,ZDHHC15,USP51,NEGR1,SOWAHA,DOCK7,IL6ST,BRINP3,LRRTM3,NME9,ITPKB,KCNA4,KCNJ3,KIF5A,CYP27C1,INSYN2,SYTL4,VWA5A,NCOA7,LSS,SMAD1,SMAD9,PIK3AP1,MAP4,MBNL1,MEIS1,DBNL,MSR1,ZNF862,MYT1,PCDH9,PCSK5,PDGFRA,GNG2,NLGN3,NALCN,CCSER2,PLP1,MTRF1L,EPB41L4B,PPM1B,PPP1R1A,PPP3CA,GRAMD1C,SYTL2,MDGA2,CNTLN,TMEM260,PTPRG,FAM120C,PTX3,RASGRF2,RGS4,RIC8B,RPRD1A,ADAL,ABCA11P,ZNF331,RMI1,DRAXIN,SCN7A,SCN8A,CNKSR2,ST3GAL3,ZNF365,SMARCE1,LIMCH1,SOX5,KDM4C,POGZ,SS18,ERBIN,SEPT8,RGL1,FGD4,SYP,SYPL1,TACR1,FAM208A,UNC5D,SYNE1,RNF216P1,CRB1,AP4E1,TIAM1,TMOD1,CSMD1,TNS1,SYNPO2,DCBLD1,PLEKHH2,TOM1L2,VSNL1,ZNF70,ZNF74,ZNF142,ZNF154,TMEM237,ZSCAN26,ZFAND5,CIAPIN1,PPP1R3F,ITM2C,WIPF2,WNK3,MVB12B,RGS7BP,FAM13C,ADAMTSL3,MSRB3,PIANP,SRGAP2B" MicroRNA hsa-miR-367*:mirSVR_highEffct hsa-miR-367*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-72 5.98E-69 4.60E-72 4.24E-71 197 862 "BRAP,RNF150,ZNF608,CC2D2A,PCDH10,KIF6,CCDC146,PPFIA1,SUGT1P4-STRA6LP-CCDC180,CDC14B,MIER1,ARNTL,CDK13,NUMB,N4BP2L1,DPY19L3,ADAM23,SEC11C,DCAF5,CASTOR3,JAZF1,DIRAS1,PTBP2,CAST,NFS1,CERS5,CD86,LRBA,CCPG1,KMT2C,RAB33A,ZFYVE9,C4orf33,SULT4A1,IQCK,ARMC8,SLC4A8,ABI3BP,SMARCAL1,CHD1L,SEC31B,RNF14,MICAL2,CSNK1G3,CNTNAP2,RIMS2,ST18,NOS1AP,HDAC9,MATR3,TOMM20,ZEB2,ZBTB24,DDX46,DLG2,GRIN3A,CPEB2,CASP8AP2,DNAJB6,EDNRB,PHC2,HIPK3,FSD1L,YAF2,PHF20L1,SUGP2,EGFR,C8orf37,RTN3,CLVS1,ABCA8,TOMM40L,GORAB,OGA,PHYHIPL,DENND2A,FAM120B,MTHFD2,C15orf41,TUBGCP4,ADAM28,KCNMB4,GNAS,TDRKH,CCDC184,GPR22,GRM5,RABL2A,MAP4K5,SMAP1,HTR5A,ZNF546,IL6ST,LRRTM3,CLVS2,KCNJ3,HECTD2,MEIS2,SRSF12,POC1B,WDR49,FXYD6,P2RY13,NELL1,NFE2L2,DNHD1,NRCAM,NUCB2,PAK3,PCSK2,PDE4B,OLA1,PIK3R1,RETREG1,LRP12,MED1,MINDY2,PPP2R5E,DCHS2,SAMD9,PSMD13,CNTLN,PTN,ZSCAN32,OCIAD1,EML5,CEP97,SLC25A48,ZNF793,ATG16L1,ZYG11B,FIGN,ZDHHC4,RNF220,PBRM1,ZFHX4,SETD5,ALG9,RAVER2,CARF,FBXW7,ATP8B4,GLDN,SALL1,DRAXIN,TRIM46,GALNT10,HSPA4L,HKDC1,NLGN1,SEC31A,WDR47,SLC8A3,SMARCE1,RCOR3,LIMCH1,UNC80,SON,TNIK,BDP1,KDM4C,SRPK2,ERBIN,SEPT3,FAM168A,FGD4,ADGRL3,TCF7,ZEB1,RPGRIP1L,WASHC4,WDR7,AZIN2,ZFPM2,CRB1,AP4E1,ERCC6L2,TPM1,TPM3,AMACR,OSBP2,LAT2,ZNF45,ZNF540,LAMP5,UPF3A,WNK1,PRDM8,LMAN2L,PCDH15,MVB12B,FZD3,DOCK8,RNF170,SSPN,FRMD6,SENP7" MicroRNA hsa-miR-548k:PITA hsa-miR-548k:PITA_TOP PITA 1.10E-72 6.16E-69 4.74E-72 4.36E-71 153 521 "CPNE2,CSMD2,FMNL2,ADCY2,USP31,PWWP2A,ZNF608,KLHL13,TBC1D14,ZNF578,TAOK1,MARCH4,MAP4K3,PKP4,CDC14B,CDK13,ZBTB10,SLC4A4,NOL4,DOCK11,FUBP1,WASF1,TMEM257,LGI1,L3MBTL4,NUMBL,CHN1,KIAA1549L,TJP2,QKI,ARMC8,GDA,TENM4,CSNK1E,CSNK1G3,ERC2,CTNND1,HDAC4,MATR3,PABPC5,ZEB2,HS3ST2,DYNC1I1,DOCK2,DPYSL2,GNE,GOLT1B,YAF2,KMT5B,COPS4,ELAVL2,ELAVL3,PAN3,KCNMB2,ERBB4,RTN3,EYA1,ACSL4,SCML2,FGF13,MEX3B,NBEA,CSPG5,OGA,CHL1,GABRG2,FAXC,SESN1,GHR,RNPS1,GPM6A,GRIA2,GRM7,PTPRT,FAM19A2,ADAMTS6,MAP4K5,MIER3,HSF2,CELF5,SMAP1,C5orf24,KCND2,KCNK2,SMAD1,MEF2C,KITLG,ZNF680,NFE2L2,NOVA1,GPR137C,CDK14,LRP12,PPP3CA,PPP3CB,PTPRD,FAM120C,ZNF493,SETD5,ALG9,ROBO1,RORB,TMEM100,HUNK,SOX8,RTN1,SEMA6D,SATB1,PPP1R9A,CPEB3,MAGI3,CHD9,FAM214B,CCDC88A,CPEB4,PALLD,PDZRN3,MYT1L,SP2,SP4,CDK19,RBM26,SRPK2,CLASP2,ITPRID2,SS18,TTBK2,ZC3H4,SYT4,CAMTA1,TAL1,CAMSAP2,DMXL2,SATB2,DOCK9,C18orf54,ZNF106,TIAM1,ZFP91,NR2E1,RIMBP2,TPD52,TRPS1,FLRT2,ZIC1,ZNF711,CELF4,EMSY,WNK3,FAM13C,PAK5,KAT6A,CPNE4" MicroRNA hsa-miR-1305:PITA hsa-miR-1305:PITA_TOP PITA 1.32E-72 7.42E-69 5.71E-72 5.26E-71 143 453 "SLC12A5,OSBPL8,SPOP,FAM135A,LRCH2,LCORL,TMEM263,RGS20,ZBTB10,ATP2B2,NOL4,SEC11C,SYNJ1,LDLRAD4,CAMK2A,RUNX1T1,TMEM257,REPS2,FOXN3,SOCS6,CLCN4,NIPBL,BTF3L4,SLC4A7,CLOCK,RIMS4,CNTNAP2,APPL1,PLCXD3,RIMS2,PPP6R2,KIAA0408,FRMPD4,TOX,SPATA2,JAKMIP2,CEP170,KLHL3,RHOBTB1,SMG7,SACS,G3BP2,CPEB2,PDCD6IP,DTNB,DYRK1A,RBM12,KMT5B,TENM1,EN2,RCAN2,DNAJC27,CLVS1,ZIC4,ACTL6B,CAMKK2,KHDRBS3,MEGF10,C15orf41,ARFIP1,GHR,SPIN1,GRIA4,PSIP1,KLF12,HMGCR,IGF1,KCNA1,KCNMA1,IPO5,STXBP5,NCOA7,MAP2,MARK1,MXI1,MYBPC1,RTL5,NFIA,NPTX1,HCN1,PCDH9,PFKFB3,CCSER2,XRN1,PLCL1,STRN3,NXPH1,PPP3CB,KANSL1,PKIA,CNNM2,BCAS3,TMEM255A,KHDRBS2,FIGN,SEC61A2,RIC8B,ZFHX4,CLIP1,SALL1,SEMA6D,ATXN1,TRA2B,PPM1E,NTNG1,CHD9,PPP4R3A,SORCS3,RIMS1,PALLD,SON,SOX11,CDK19,TAB2,LARP4,LRRC4,MPRIP,TTBK2,FGD4,ARHGEF9,SYPL1,CAMSAP2,TCF4,DMXL2,RPGRIP1L,SZT2,ZFP91,HEY2,TMOD1,DOK6,TRPC3,TRPS1,SGK3,FLRT2,TBC1D15,XPO1,ZIC2,EMSY,CADM2,KAT6A,PHTF2,JMJD1C,CPNE4" MicroRNA hsa-miR-1296:mirSVR_lowEffct hsa-miR-1296:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.99E-72 1.12E-68 8.56E-72 7.89E-71 186 774 "RALGAPA1,AS3MT,ERMN,PTCHD1,HECW2,OSBPL1A,AMPD3,LCORL,PPP4R4,CDK13,ALDH4A1,ATP2A2,NOL4,ADAM23,TTLL9,LINC00906,SGCE,DDR1,CACNB2,CACNG1,CAMK2D,CAMK2G,TRIM41,VXN,CCKBR,METTL6,NEURL1,CDC42,LRRFIP1,NUMBL,SRSF11,PLEKHB1,CASC2,CNGA3,BTF3L4,COL9A3,IFFO1,IGDCC3,CP,RGS6,ATRNL1,KIAA0040,CMTM5,KATNAL2,FRMPD4,LONRF1,MAML1,SCRN1,GIT2,ELMSAN1,ZEB2,KIAA0753,DDX46,POM121,CHRDL1,DLX1,DNM2,ATN1,GNE,WDPCP,RASGRP1,ING4,CERCAM,VPS13B,COQ7,ERBB2,REEP2,CEP78,FER,GTF2IRD2,KIAA1109,CAMSAP1,ATP5PD,SYT3,C2orf88,TMEM107,CELF1,SARAF,TBR1,AP4B1,FYN,ZNF274,GATM,ADAM28,GLYR1,TOX3,ZNF638,LUZP2,LNX1,ADGRA3,ATF7,CECR2,CNTRL,GRM7,LINC00839,MFSD2A,HMGCR,HTR2A,LRRTM3,GPR62,KCNJ3,KCNJ11,MAT2A,MBP,MDM4,MEF2C,CD200,MPP2,ZNF862,NAP1L2,P2RY13,NHLH1,OGG1,PDE2A,GPR173,PURG,C11orf49,PPM1B,PROX1,SIDT1,WDR25,PTCH1,BDNF-AS,PTPRN2,PTPRZ1,PEX5,ACSM5,MARCH1,TMEM255A,RALGDS,RASGRF1,RBBP6,HKR1,MSANTD2,DPF2,RGS7,ARHGEF10L,ALG9,SNX22,KIAA0895L,ZNF331,ATXN2,SOX6,GALNT10,ITSN1,DOCK10,FBXO11,CTXN2,WDR37,SLC12A2,SLC14A1,NAPB,NAXD,SMARCD3,MYO16,SON,BDP1,SOX10,SPTAN1,IQSEC2,RBM26,FGD4,FAM208A,SYNE1,PHF24,PCDHB4,CRB1,ENHO,TJP1,ANKRD24,TPM3,ZNF346,ELP5,SSBP2,RFTN2,UBE2H,OSBP2,XPO1,ZNF24,CELF4,POLR3H,WNK1,LINC02210,LMAN2L,ST8SIA2,JPH3" MicroRNA hsa-miR-658:mirSVR_lowEffct hsa-miR-658:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.10E-72 1.18E-68 9.07E-72 8.35E-71 216 1030 "CPNE2,ACHE,CSMD2,ADD1,ADD2,PNMA8B,ESYT2,AMPD3,ANK3,CCDC146,PHF12,PKP4,AMER3,SFMBT2,LINC00173,MARK4,ASPH,DDX3Y,SLC2A11,LINC00847,CDK5R2,CFAP410,CA12,CACNA1D,CALB2,CALM1,SCARB1,CD81,MAGI1,GPR37L1,CNOT8,TAOK2,EPS15L1,NRXN3,PPT2,IQCK,FAM149A,CABP1,MFSD4A,SLC35F1,CRY2,CSF2RA,FEZ1,MICAL2,CSNK1E,PPP1R16B,UBXN2A,CTNND1,RUBCN,EDRF1,MYADM,DCAF8,RIMS3,MYEF2,C2CD2L,MAGI2,GUCD1,RHOBTB1,SMG7,NTM,USP3,DPH1,ATN1,DTNB,DNM1L,EEF1A2,SGK2,FCF1,MBNL2,TMEM132E,EML1,EN2,ENO2,MFSD10,DMTN,RABEPK,SLC43A2,ERBB2,ERCC2,CLVS1,ZNF461,TUBB3,CHST15,STRADA,ZNF589,FER,FHL1,SEMA6C,NOP56,CELF1,ABLIM2,STAG2,INPP5K,GPR162,GGT5,C1QL1,RAB30,GP1BB,GRID1,SPACA9,GRM1,LINC01089,ZBTB49,FAM107A,RNFT2,HRH3,ARHGAP19,C5orf24,LRRC25,INSM1,LRRC4B,SFXN5,CLEC18A,MAN2A2,CPNE9,MYO7A,NINJ2,NRGN,OGG1,PAH,PCSK5,PRTG,OLA1,ZDHHC8,NALCN,FAM216A,FTO,PURG,MAPKAP1,FA2H,PRKCG,PKN2,TMEM104,PTHLH,PXK,RIPOR1,PID1,FEZF2,BSDC1,UBR7,RGS3,RGS12,ARHGEF10L,RNASEL,ALG9,PNMA8A,KIAA0895L,MEG3,NCBP3,S100B,SCP2,FBXO11,ST3GAL3,PEX26,DHX30,SMTN,LIMS2,SLC6A8,SLC8A3,SMARCC2,SORCS3,RCOR3,RIMS1,SNRPN,FAM219A,TNIK,BDP1,FNBP1,ZSWIM8,CLUAP1,KDM4C,SPTB,NFASC,C11orf87,TAB2,NKAIN2,SS18,STAU1,SEPT8,KANK1,SYN1,SYP,SEMA4A,IQCE,MGRN1,DMXL2,CUX2,TCF7L2,TPCN2,PCDHB9,USP32P1,ARHGAP9,SIK3,KCTD2,RASD2,TPM3,C9orf85,PRMT8,TSC2,UBTF,BCL2L13,LGI4,ZNF24,ZNF28,TRIM9,ZFP41,ATP6V0E2,PRDM2,DNALI1,HPS4,CIAPIN1,WNK3,DOCK8,ST7,CAMK1G,NUP214" MicroRNA hsa-miR-543:TargetScan hsa-miR-543 TargetScan 2.14E-72 1.20E-68 9.22E-72 8.49E-71 158 559 "ABR,C3orf14,FMNL2,ADARB2,ADCY6,PWWP2A,ABCD2,CASK,NOL4,DOCK11,BCL7A,IL33,LDLRAD4,CACNB4,CALB1,CAMK2G,MAP7,CERS5,ARHGEF2,REPS2,CDH2,DCLK1,DLGAP2,CHN1,NRXN3,NMT2,DNAJB5,NIPBL,ARMC8,AKAP6,AKAP5,RCHY1,AHCTF1,CLOCK,HAPLN1,OSBPL3,CTH,PYGO1,GAPVD1,RASSF2,MATR3,DNAL1,DBT,ELMSAN1,MFAP3L,DDX46,ARNT2,DLX1,NR1D2,CPEB2,KLHL5,PLXNC1,ELAVL2,ELAVL4,EIF1,EN2,EPB41,EPS8,ERBB4,CEP85L,CLVS1,FGF12,PCYOX1,NPTN,GABRA1,CAB39,FAM184B,NCKAP1,IQGAP2,FAXC,GFRA1,PPARGC1A,GJB1,RAB30,GNAO1,GPT2,NUDT21,GRIK2,GRM1,GRM5,GRM8,IL1RAPL1,MFSD2A,FAM222A,RASSF8,BACH2,HNMT,NEGR1,AGFG1,DOCK7,KCNA1,KCNA4,KCND3,KCNQ3,IPO5,LIFR,LMO1,MEIS2,MIA2,RSPO2,MXI1,HCN1,NUMA1,KCNK10,PBX1,PCDH8,PCSK1,PCSK5,PDE4D,GNG2,CDK14,SCHIP1,PPP2R2C,CEP41,PKIA,PROX1,CNNM2,PTPRD,EML5,FIGN,KLHL11,RORB,PTGR2,AP1AR,AMER2,SCN2B,SCP2,HSPA4L,FAM102A,BTBD3,PKNOX2,CPEB4,EMC1,ARHGAP26,RBM26,NPAS3,LMO3,ATP11A,DMXL2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,AP4E1,NACC2,CBX5,ASXL3,HEY2,LRRC8A,CADM1,FLRT2,LAMP5,PRDM10,RGS7BP,FXR1" MicroRNA hsa-miR-1184:mirSVR_highEffct hsa-miR-1184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.16E-72 1.21E-68 9.29E-72 8.56E-71 204 925 "DGCR6,EMILIN3,ARID1A,CSMD3,KLHL32,GRAMD1B,TAOK1,ZNF687,MAP4K3,SUGT1P4-STRA6LP-CCDC180,LGR5,MADD,ARHGAP5,CADPS,NUMB,ATP2B3,ADGRB3,DST,ARHGEF7,CASTOR3,CACNB2,PTBP2,NGB,CAMK2G,VXN,VSTM2A,NFS1,LGI1,EPS15L1,IGFBP7-AS1,TPP1,ARMC8,LETMD1,MFSD4A,CDC42BPB,SNCAIP,SEC24C,FEZ1,VCAN,PDE4DIP,APPL1,CTNND1,TCAF1,HDAC4,DBI,ARMCX2,DNAJC6,JAKMIP2,ZEB2,RUSC2,DDX46,RHOBTB1,SACS,CHRDL1,EXOG,GRIN3A,RAB39B,DPYSL2,DUSP9,DNAJB6,ABCC5,AASDH,ANKRD46,YAF2,MBNL2,ABI2,C3orf18,EPHB1,GPHN,DENND4A,ADGRV1,EYA1,TOMM40L,FCGRT,FGF1,OLFM1,RGPD5,SEMA6C,NELFCD,FOLH1,ATP2C1,NEK6,SYT17,DISC1,DNER,TUBGCP4,ARFIP1,PCDH11X,RAB40B,GNAO1,GNAS,ZNF782,WDFY3-AS2,FUT10,PCLO,STMN2,GRIA2,GRIA4,PRDM5,GRM7,LINC00839,ZBTB49,IRAK3,GPR45,NKD1,ITPKB,KCNB1,KCND1,KCNJ3,KCNJ9,KCNMA1,KCNN3,KLC1,TTYH2,MRPL42,MYO7A,ZNF862,NELL1,NF1,DNHD1,NPPA,SETD4,OPHN1,SNTG1,PAK3,ENPP2,GNG2,ST8SIA5,DRAM2,CRLS1,RELN,NDUFS7,BCAS3,GDPD2,PIGG,PLPPR1,MTMR10,TMEM260,SLC25A48,RALGDS,FAT4,RADX,RFX4,RFX5,TTLL7,RNASEL,ELP2,ADAL,LRRK2,NCBP3,SCN3A,SCN7A,SUPT20H,SCAF8,ASAP3,DOCK10,NTNG1,NLGN1,SLC11A1,ATF7IP,SORCS3,SMARCD3,SMARCE1,RCOR3,LIMCH1,FNBP1,ZSWIM8,HECW1,ERC1,SPTAN1,NPAS3,SRPK2,ATP10B,PHLDB1,SYT11,FGD4,TACR1,DDHD2,TBCEL,TPCN2,SYNE1,DICER1,CRB1,ERCC6L2,HEY2,RIMBP2,TPM1,C9orf85,RGMB,PRMT8,PPIL6,UBE2H,FRRS1L,TRIM9,CELF4,WNK1,SLC17A7,WNK3,PDSS2,UBE3B,SMIM8,CASC15,ZNF248,SENP7" MicroRNA hsa-miR-622:mirSVR_highEffct hsa-miR-622:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.41E-72 1.35E-68 1.04E-71 9.55E-71 187 783 "SDE2,NDRG3,AXIN2,SORCS1,PWWP2A,KIAA1211,DISP3,AMPH,DPP10,LRCH2,PPFIA1,API5,SHTN1,MIER1,RGS20,ATP1B3,ATP2A2,BTK,JAZF1,CACNA1B,KALRN,PTBP2,MAP7,NFS1,USP2,LARGE1,SLIT2,RAB28,QKI,AKAP7,BTF3L4,SLC4A8,TBPL1,ACBD5,MFSD4A,RGS6,CST3,APPL1,KIAA0586,DGKB,DGKG,DAPK1,EXOG,USP3,DTNA,E2F6,FAM135B,YAF2,PHF20L1,EYA1,ABCA8,FAM198B,FCGR1B,FKTN,FDFT1,TESK2,ZNF589,POLK,SUCO,FOXG1,NELFCD,FOLR2,SORBS1,SMC2,ST6GALNAC3,AP4B1,DOT1L,SDCBP2,MEGF10,GABRA1,GALNT15,B4GALNT1,ZNF234,DISC1,GGT7,GHR,POLL,EML4,GRIA2,NR3C1,ATE1,PSIP1,RBPJ,IL6ST,ZNF385B,METTL21A,KCNB1,KCNN3,LAMA2,STMN1,LMO2,ZNF667-AS1,MBD1,MBNL1,TM6SF1,MDM4,MEIS1,MMP16,MOG,MYO7A,PABPC1L2A,NAP1L1,RCOR2,NELL1,VWA2,DNHD1,SLC11A2,NUCB2,CLDN11,SNTG1,JAKMIP1,PRRX1,SEPT4,IRX1,PPP2R5E,MASP1,PSMD13,PIGG,PTK2,ZSCAN32,TMEM255A,USP47,SUSD4,ARID4A,RADX,KHDRBS2,MORC4,RGS7,RNF220,FBXW7,ATP8B4,PRR5L,LGR4,SYNDIG1,SAFB,SALL1,SATB1,CSRNP3,LRFN5,PEAR1,NTNG1,SHC4,FNDC3A,FHOD3,DHX30,PKNOX2,SLC14A1,SLC22A4,NAXD,MYO16,ZSWIM8,SP4,DBNDD2,KIF1B,RBM26,SS18,ACSBG1,PRRC2C,PLCB1,TACC1,MTCL1,CAMTA1,KLHL4,ANO4,CYB561A3,CRB1,TMOD1,RIMBP2,PDSS1,TRO,ANKRD20A2,HIRA,CCDC14,WIPF1,ZBTB14,SPIRE1,SMARCAD1,SLC38A1,ADAMTS9,HPS4,PCDH15,FZD3,RTN4,PHTF2,ZNF248,ZDHHC20,SLC39A12" MicroRNA hsa-miR-21-5p:Functional MTI Functional MTI miRTarbase 2.45E-72 1.38E-68 1.05E-71 9.71E-71 165 611 "SNX30,ESYT2,OSBPL1A,LCORL,PPFIA4,APAF1,APC,GPAM,MTMR9,BCL7A,FUBP1,KRIT1,LONRF2,LRRFIP1,SRSF11,FOXN3,SOCS6,CASC2,CLU,HECTD1,NIPBL,ACBD5,CLOCK,PREPL,HAPLN1,OSBPL3,SOCS5,APPL1,EDRF1,BOC,DOCK4,GAPVD1,DCAF8,ZFYVE16,TMEM170A,SCRN1,MYEF2,DDX46,DMD,DMTF1,GNE,DNM1L,EDIL3,ANKRD46,HIPK3,RASGRP1,PHF20L1,EGFR,EIF5,PLEKHA1,ELAVL4,PAN3,ERBB2,TESK2,FGF12,FOXO3,NBEA,STAG2,RAPGEF6,SESN1,MALT1,SPIN1,FERMT2,GPD2,CNTRL,RFFL,HPS5,HMGB1,HNRNPK,DOCK7,IL12A,STXBP5,LAMP2,LIFR,MBNL1,MDM4,MEF2C,MEIS1,PPM1L,SAMD5,MYO9A,NEK1,NFIA,DDR2,OLR1,OXTR,PBX1,PFKFB2,ABCB1,SERPINI1,PIK3C2A,PIK3R1,PURG,PPARA,PRKAB2,SNRK,PTK2,PTX3,CEP97,USP47,ARID4A,ZYG11B,REV3L,FIGN,PBRM1,ZNF532,MRAP2,AP1AR,SATB1,ASRGL1,CPEB3,DOCK10,FBXO11,ST6GAL1,NUBPL,BTBD3,KANSL3,SIRT2,BTBD7,ATF7IP,TET1,ZNF667,SMARCA4,LIMCH1,PALLD,FAM126B,SOX2,SOX5,FNBP1,MYCBP2,CDK19,SRPK2,ITPRID2,ELOVL4,SYNE2,VPS13A,ANKRD28,DDHD2,ATMIN,TRIM2,WDR7,ARHGEF12,DICER1,TGFBR3,TIAM1,TLR4,TP53BP2,TPM1,NR2C2,SGK3,CADM1,CCDC14,NSD2,ZBTB38,WNK1,RNF103,NAV3,WNK3,EPM2A,RTN4,KAT6A,CERS6,RSPRY1,NETO2,SOCS4" MicroRNA hsa-miR-34a:mirSVR_highEffct hsa-miR-34a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.92E-72 1.64E-68 1.26E-71 1.16E-70 192 825 "ASIC2,SYS1,KDM5D,ADCY6,ADD2,ADRA1D,MTUS1,GPR158,HACE1,KIAA1324,LRRC7,ALCAM,DOC2A,ANK2,ANK3,PPFIA1,PKP4,CNTNAP1,VAT1L,TMEFF1,NCOA1,DPY19L3,ADAM23,BCS1L,DST,SYNJ2,ARHGEF7,JAZF1,OSGIN2,WASF1,CALB1,KALRN,CERS5,INA,DGKI,ZMYM4,EVI5L,LGI1,TIGD7,NUMBL,EPS15L1,RAB33A,TMEM59L,SULT4A1,HECTD1,AKAP6,SLC25A27,SLC4A7,MYRIP,PREPL,CLIP3,TRIM69,CS,LRIG1,CNTNAP2,ERC2,PNPLA8,CTNND2,NOS1AP,IST1,DGKB,BRINP1,GIT2,ELMSAN1,MAGI2,RCAN1,DNM1L,E2F5,SYT15,FAM13A,KMT5B,RGS17,TMEM35A,C8orf37,SPEG,SIRPB1,NRN1,ACSL4,SUCO,SCARA3,HPCAL4,FOXG1,PSD2,SLC37A3,NOP56,ZCCHC17,HVCN1,GABRA3,BRPF3,ZMYND11,GHDC,TUBGCP4,TUBA8,MSTN,LOXL3,GNAO1,GNAS,GOLGB1,CCDC184,GPR22,PCLO,GRID1,GRM7,NXPH3,ARHGAP36,GABARAPL2,IGSF1,ITPKB,KCNA2,KCNK3,KIT,VWA5A,HECTD2,CLEC18A,MDM4,KITLG,MYCN,CCDC13,NF1,NNAT,CNOT4,OPHN1,CDK18,PDGFRA,GPR85,GNG2,GDAP1L1,ST8SIA5,JAKMIP1,PURG,STRN3,ING3,CRLS1,PKIA,SIDT1,CNTLN,MTMR10,PTPRD,EML5,PTX3,PEX2,ZNF844,PPP2R3C,TMEM255A,FAT4,SLC6A15,RIC8B,RNASEL,ZFHX4,LGR4,SATB1,ATXN7,ELMOD1,ITSN1,RUFY2,KDM4D,SORCS3,DMRTC1,KIF13A,SNRPN,PALLD,PDZRN3,KIF1B,POGZ,ZC3H4,ARHGEF9,SYT1,DDHD2,CAMTA1,FAM208A,ANO4,ATMIN,SATB2,DOCK9,USP32P1,AHCYL2,RNF216P1,ITGB3BP,TNR,TPD52,TSN,CADM1,PLEKHH2,BCL2L13,SYNC,LMAN2L,NAV3,DOCK8,JMJD1C,TIGD6,NETO1,JPH3" MicroRNA hsa-miR-623:mirSVR_highEffct hsa-miR-623:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.12E-72 2.32E-68 1.77E-71 1.63E-70 179 721 "NDRG2,CCDC85A,RNF157,BEND6,SLC44A5,GPR158,ADGRF5,PPFIA1,ARNTL,DDX3Y,ATM,ATP2B3,TTLL9,BBS2,NRP2,CFLAR,CACNB2,CALB1,CALB2,KALRN,CCK,MTMR7,DCLK1,LGI1,CHM,CASC2,JAM2,TAOK2,IGFBP7-AS1,ZFYVE9,NIPBL,ZNF521,ZFP28,FAM171B,CRHBP,HAPLN1,SNCAIP,SEC24C,PHACTR3,APPL1,GREB1,RIMS2,ZSCAN23,RUBCN,CYBB,KATNAL2,ARMCX4,DDX46,RHOBTB1,NTM,FARSB,EDNRA,KLHL5,CELSR3,TMEM35A,C8orf37,EIF1,EPHB1,RTN3,CLVS1,TMEM132C,CHST15,TOMM40L,STRADA,GORAB,MED12L,IP6K2,NOP56,TACC2,USP16,ZNF512,GABRA3,ILDR2,DENND2A,GLS,ADGRA3,FUT10,GPR19,STMN2,PLCD4,GRM1,ADAMTS6,HMGCR,HNMT,NKD1,DOCK7,LRRCC1,IL6ST,LRRTM3,ITGAV,KIF5C,CYP27C1,LMO2,ARHGAP12,MBD1,MBNL1,SYT9,MDM4,MEIS1,MEIS2,SRSF12,BLOC1S2,NASP,NOVA1,GPR137C,PCMT1,GPR85,PIK3CD,FAM218A,PKM,EXOSC10,SH3KBP1,PPP2R2C,PRKACB,MAPK10,HYDIN,SYTL2,PSMD13,CNTLN,MTMR10,PTHLH,TMEM260,PTPRB,PTPRD,PID1,OXR1,FIGN,RGS10,PRIMA1,SLC25A36,NEK11,ZNF671,ATP8B4,TCP11L1,TMEM156,ATXN2,ATXN7,BCAN,NLGN1,ST3GAL3,SLA,ZNF365,YPEL4,SLC9A5,SLC12A2,EPC1,SMARCE1,SOX2,DOK5,UNC5B,ZC4H2,GANAB,PRRC2C,CAMSAP2,ZFP90,TRIM2,TCF12,WDR7,SIK3,FAM200B,DICER1,CRB1,TLR4,NR2E1,HEY2,CDK20,ZNF384,TRIO,PCDH20,KCNT2,PLPP4,ZNF154,ZSCAN26,ZFAND5,KCNAB1,EPM2A,CASC15,CERS6,RNF170" MicroRNA hsa-miR-885-5p:mirSVR_highEffct hsa-miR-885-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.58E-72 2.57E-68 1.96E-71 1.81E-70 168 636 "NDRG3,KIAA1211,NME5,SEMA6A,ARHGAP20,FAM135A,MAP4K3,USP28,PARG,API5,SHTN1,STK33,DOCK11,SYNJ1,SCAPER,JAZF1,PRMT9,PTBP2,SPAG9,MAP7,CDC27,CDC42,LRRFIP1,CHN2,JAM2,KIAA1549L,CLTA,QKI,SLC4A8,RCHY1,VCAN,PHACTR3,CTH,NRSN1,CYBB,HDAC9,DCAF8,TOX,ARMCX4,ZNF804A,RHOBTB1,SNAP91,DLG2,HS3ST4,USP3,CPEB2,ABI1,PDCD6IP,ARRDC4,FCF1,RASGRP1,FRY,FAM13A,PHF20L1,EIF4G2,ELAVL4,TMEM74,RTN3,EYA1,ARMCX1,DLC1,TOMM40L,KIAA1109,UBE2E3,MEX3B,SGIP1,FOLH1,ATP2C1,OGA,HRASLS5,GABRG2,ARPP21,ADAM28,GPR75,GLS,INSM2,NUDT21,EML4,GRM8,PSIP1,ADAMTS6,RASSF8,NXPH2,HNRNPK,SOWAHA,IL6ST,TUBB2B,KIF2A,KTN1,LMO1,SYTL4,MBNL1,MDM4,AFDN,ERICH3,JAKMIP3,CTNNA3,MYO9A,NEUROD1,CNOT4,SLC11A2,NRCAM,LOC100128398,PCDH9,PDE4D,CYTL1,CDK14,FAM218A,PCDH18,HMGCLL1,ING3,SNRK,NWD1,OXR1,RASGRF2,ARID4A,KHDRBS2,RET,RNASEL,ZFHX4,C12orf49,CARF,LRRK2,TRAPPC13,AMER2,SCN3A,LRRTM4,SCN7A,SH3BGR,KIF21A,SH3GL2,CPEB3,NTNG1,FAM81A,PPP4R3A,SEPHS1,SLC12A2,NAPB,TET1,SMARCE1,SNRPN,UNC80,ENKUR,ZNF423,SSTR2,ERBIN,SYPL1,TBCEL,ATMIN,SIN3B,DMXL2,SATB2,TPCN2,SLC44A1,ZFP91,HEY2,KAT6B,TMEFF2,PLEKHH2,EMSY,ADAMTS9,NAV3,WNK2,GOPC,PAK5,HNRNPA3,CASC15,CBLN2" MicroRNA hsa-miR-154:mirSVR_highEffct hsa-miR-154:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.19E-72 3.48E-68 2.65E-71 2.44E-70 196 862 "TTYH1,KLHL32,ADD1,BRAP,MTUS1,GPR158,OGT,ANK3,LGR5,CDK13,CCDC74A,TMEM108,ATP2B1,ADGRB3,BBS2,KSR1,BMPR1B,SYNJ2,ARHGEF7,RAB29,CALB1,PTBP2,CAMK2G,SYT6,CBS,MTMR7,LRRFIP1,CFL2,SRSF11,FOXN3,CHM,ZBED5,NRXN3,PLAA,MAP4K4,ARMC8,CLOCK,CS,SUSD5,SOCS5,CST3,UBXN2A,CTH,ZSCAN23,LIN54,DGKB,RABGAP1L,CPEB2,DMTF1,ACOT8,ABI1,RCAN1,DTNA,ECM2,ABCC9,GOLT1B,E2F5,KLHL5,FRY,FAM13A,GOLGA7,COPS4,RCAN2,RTN3,WAC,CEP78,KAT8,GORAB,SEC24B,FGF14,FHL1,NPTN,CHL1,GABRG2,IQGAP2,DISC1,GATM,LYVE1,HPGDS,ZNF638,INSM2,GNAS,GOLGB1,ADGRA3,LPAR4,CECR2,ATP2B1-AS1,GRM7,KAT7,PSIP1,MIER3,ELOVL5,OPALIN,TCEAL6,SOWAHA,SCIN,KCNK2,HECTD2,MAP4,MDM4,MKLN1,AFDN,XRRA1,MOBP,NRBP2,NAP1L1,CNOT4,PCBP3,PAK3,PCSK2,FAM218A,PRRX1,MED1,MINDY2,PPP2R5E,GRAMD1C,GDPD1,MASP1,WBP1L,MDGA2,PTHLH,TMEM260,RAB5B,TMEM255A,ARID4A,RET,GTDC1,TTLL7,ZNF532,TMEM206,TMEM100,GLDN,STK32B,MAP6D1,TRAPPC13,SALL1,SCN3A,FNIP1,SLC30A10,SUPT20H,HSPA4L,ZFP30,ASAP3,CPEB3,ANKRD6,PPP4R3A,PKNOX2,CPEB4,SORCS3,SMARCD3,SNRPN,SOX3,SP4,EMC1,SPP1,RBM26,LARP4,NXT2,NEK4,ARHGEF9,PLCB1,SYT4,KAZN,TBCEL,ANO4,SATB2,CUX2,TCF12,PCDHB4,CRB1,FBXL16,TIAM1,HEY1,ELP5,AMACR,RFTN2,ZNF709,TBC1D15,CLDND1,CFAP298,ZFP37,KCNT2,AGMO,TMEM237,ZSCAN26,MFF,CADM2,HPS4,PCDH15,DNAH10,FZD3,FBXO36,TTC7A,FXR1,NETO1,GAN" MicroRNA hsa-miR-510:mirSVR_highEffct hsa-miR-510:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.35E-72 3.57E-68 2.72E-71 2.50E-70 177 707 "CLK4,KDM5D,CSMD2,ADD3,ADRB2,LRRC7,GPRASP2,GPAM,BCAS1,CADPS,SLC4A4,ATP2B1,DPY19L3,RGS11,KSR1,C5,WASF1,CLDN10,LDB2,USP6,CDH18,LGI1,MAGI1,CCPG1,SRSF11,PLEKHB1,CASC2,CLTB,TMEM59L,DNAJB5,FAM149A,LETMD1,RTTN,HS3ST5,CHD1L,GDA,CLIP3,CTH,GPRASP1,TOX,MATR3,KCTD8,DAPK1,MAGI2,ZC3H11A,GSDME,DDX46,G3BP2,RABGAP1L,EXOG,GRIN3A,DNM1L,GOLT1B,PHC2,ANKRD46,PHF20L1,RCAN2,LRRC17,EPHB1,EPS8,F5,TUBB3,KIAA1109,FGF12,IP6K2,SLC37A3,NELFCD,WDR83,JKAMP,SMC2,ATP2C1,PNMA2,DKK3,HRASLS5,ZNF44,RAPGEF6,GATM,TNRC6A,CBX1,MAP7D2,GNAS,GPD2,GPM6A,TDRKH,PRLHR,NUDT21,GRIA4,COQ10A,SCIN,TUBB2B,LRRTM3,KCNH2,MAT2A,MBD1,MBNL1,KCTD6,MTTP,RSPO2,MXI1,NFE2L2,NINJ2,CNTN3,PDE1C,PDGFRA,PDPK1,FAM216A,EPB41L4B,SH3KBP1,PPP2R5E,MAPK4,HYDIN,SAMD9,GON4L,MDGA2,CNTLN,PTAFR,PTPRZ1,ZDHHC14,RET,SEC61A2,C12orf49,PNMA8A,GSTCD,RORB,TMEM206,ELP2,HUNK,SCN2A,SCN7A,FNIP1,SLC30A10,MAGI3,SLA,PPP4R3A,SLC8A1,ATF7IP,SORCS3,SMARCD3,RCOR3,DOP1A,NPAS3,SRPK2,PBLD,NEK4,ADHFE1,FAM168A,SLC37A2,C12orf76,TACR1,DNMBP,AGTPBP1,FBXW11,ANO4,PCDHB7,PCDHAC2,USP32P1,TNS2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,FAM200B,ASXL3,TLR4,CADM1,CCDC136,VAV2,MEAF6,SF1,EMSY,DNALI1,STMN4,URM1,ST8SIA2" MicroRNA hsa-miR-448:PITA hsa-miR-448:PITA_TOP PITA 6.80E-72 3.82E-68 2.91E-71 2.68E-70 140 438 "ABAT,ADD1,ADD3,UNC5A,HECW2,DOC2A,ANK3,GPAM,API5,ARNTL,NCOA1,DCAF5,SYNJ1,PTBP2,CLDN10,INA,SEPT7,CDC42,CDH10,SRSF11,SYNPR,SULT4A1,ARHGEF6,MYRIP,ZNF521,SOCS5,SLITRK5,PLCXD3,KIAA0408,DOCK4,FRMPD4,TOX,DAPK1,DCC,DNAJC6,ZEB2,COPS7A,BLOC1S6,RHOBTB1,CPEB2,MAMLD1,GOLT1B,KLHL5,FRY,MBNL2,EGR3,PAN3,KCNMB2,GPHN,ETV1,FOXO3,AFF2,NBEA,KBTBD12,PHYHIPL,GABRB3,MSTN,GLRB,GLS,RAB40B,FERMT2,GPM6A,RAPGEF4,GRIK2,ZHX1,BACH2,SMAP1,JAK1,KCNA1,KCNA4,KCNB1,PACRG,SYT9,MEF2C,MEIS1,MITF,MYH3,NEXMIF,CNTN3,PCDH8,PCDH9,PDE4D,GPR85,SH3KBP1,PRKAB2,PRKCZ,MTMR10,PTPRD,PTPRE,FAM120C,RAB5B,OXR1,TTLL7,ZFHX4,SETD5,RAVER2,ROBO2,RORB,WLS,ATXN1,HSPA4L,SH3GL2,CHD9,NLGN1,ABLIM3,WDR47,SLC12A2,TMCC1,MYT1L,ZCCHC24,SOX11,CDK19,RBM26,SRPK2,SS18,SYN1,SYN2,ANKRD28,SYT4,ATP11A,TACC1,FBXW11,EHBP1,TCF4,ZEB1,DOCK9,PSD3,PUM2,CRTC1,TEK,SIRT1,HHIP,TLR4,AMOT,VLDLR,ZNF711,FZD3,FXR1,FRMD6,GAN" MicroRNA hsa-miR-106b-5p:Functional MTI Functional MTI miRTarbase 7.52E-72 4.22E-68 3.21E-71 2.96E-70 222 1091 "ADAR,FMNL2,ADD1,FZD9,SORCS2,ZNF578,MARCH4,KIF6,SEMA7A,USP28,APC,GPAM,DGKD,APP,SHTN1,CAPRIN2,ATP1B3,ATP2B1,MTMR9,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,CDK5R2,FOXK1,TRIM41,MAP7,RUNX1T1,FMNL3,CBFA2T2,ZBED1,CDC42,DIS3L,CFL2,EPS15L1,ZFYVE9,CLTC,QKI,BTF3L4,SLC4A7,ACBD5,IGDCC3,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,FEZ2,SOCS5,UBXN2A,CYBB,DCAF8,KIAA0513,ZFYVE16,DNAL1,YTHDC1,ELMSAN1,PLEKHM1,FBXL5,CEP170,SMG7,SACS,RABGAP1L,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,GOLT1B,E2F5,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,USP16,TPK1,FYN,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,MMADHC,CRCP,RNPS1,RAB30,TNRC6A,CBX1,LUZP2,GNAS,GPM6A,FUT10,RAPGEF4,NR3C1,CIT,KAT7,MFSD2A,FICD,HAS2,HMGB1,HMGCL,ITPKB,JAK1,KCNB1,KCND3,KIF5C,CAMK2N2,ARHGAP12,SMAD9,PIK3AP1,GPR155,MAT2A,CHIC1,SCAMP5,AFF1,SESN3,MTR,MXI1,NBL1,NEFH,CNOT4,OCRL,PDPK1,PFKFB2,PFKP,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRRX1,PPM1B,KANSL1,PRKACB,PRKCB,MAPK9,VPS13C,SLC22A23,GON4L,PXK,OCIAD1,RAB5B,CEP97,ATG16L1,OXR1,ZNF532,TMEM100,ATAT1,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,RUFY2,BTBD7,CMTR2,FAM126B,SON,FNBP1,SP2,SP4,EMC1,SMOC1,STAC2,SYT4,ANKRD12,CAMTA1,WWC1,TCF4,TCF7L2,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,DDHD1,TMPO,PARD3,TPM4,RGMB,NR2C2,PDSS1,TSC1,UBC,NSD2,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-1265:mirSVR_highEffct hsa-miR-1265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.68E-72 4.31E-68 3.28E-71 3.02E-70 200 897 "ABAT,KDM5D,FAM43B,XKR4,CSMD3,DPY19L2P4,HECW2,KCTD16,WDR35,TXNDC16,SMIM17,SPOP,OGT,PKP4,APAF1,TMEM263,ATP2B1,ATP2B3,ATP6V1G2,CFLAR,SYNJ1,DDR1,PTBP2,CAMK2A,VXN,CAST,ZNF501,CD38,CD81,CLGN,KMT2C,PLAA,NIPBL,TMEM155,FHL5,ARHGEF6,MAGED1,NRG2,FAM171B,AKAP12,TENM4,ATRNL1,RIMS4,PDE4DIP,CYBB,RIPOR2,MAML1,ZEB2,CHRDL1,DMD,DOCK2,DPYSL2,ATN1,GOLT1B,E2F6,EDNRB,FCF1,TMTC1,EMX2,VPS13B,EPB41L1,RCSD1,EXTL2,GMPR2,CLVS1,SH3YL1,KAT8,POLK,SCARA3,PDLIM5,ST6GALNAC3,NRG3,FAM120B,DISC1,SULT1C4,GK,COPS8,GNAS,GOLGB1,NUDT21,CECR2,RAPGEF4,GRIA2,HPSE2,MSL1,FAM95B1,C5orf24,ZIC5,IL6ST,BRINP3,LRRTM3,KCNN3,KLRC2,HECTD2,CLEC18A,MAOB,MBNL1,SHC3,MEF2C,MEIS1,SRSF12,MEST,MOG,MYCN,NELL1,NF1,NFE2L2,NOVA1,DNHD1,OPA1,GLIPR1L2,PDE1A,PDE3A,PDE4D,PDGFRA,PFKFB2,SERPINE2,PMP22,PSAT1,MED1,PPP2R5E,HYDIN,VPS13C,DEF8,MDGA2,PTHLH,TMEM260,PTPRE,PTPRG,PID1,RADX,ZYG11B,TRIM68,PBRM1,SETD5,CARF,BAALC,GLDN,ACER3,ATAT1,WLS,RTKN,SCN3A,FNIP1,SEC14L1,SUPT20H,ITSN1,SH3GL3,CHD9,FNDC3A,NLGN1,CTXN2,SLC1A3,SLC4A3,EPN2,RUFY2,SLC8A3,SORCS3,CDK5RAP2,LIMCH1,RIMS1,SON,SOX2,DBNDD2,LRRC4,NXT2,GANAB,FGD4,SYT1,EXOC7,TAL1,FAM208A,ADGRL3,ANO4,SYNE1,FRYL,FAM124A,TPM3,SYNPO2,METTL3,TRO,DCBLD1,SSBP2,TTC3,PITPNB,PLEKHH2,BCL2L13,MEAF6,CCDC14,CLDND1,XRCC4,ATP6V0E2,PLPP4,ZNF154,FSTL5,EML6,UPF3A,CA10,CASC15,ADAMTSL3" MicroRNA hsa-miR-92a-2*:mirSVR_highEffct hsa-miR-92a-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.30E-72 4.66E-68 3.54E-71 3.26E-70 189 805 "CPNE2,KDM5D,ADD1,ADD2,PTCHD1,LRFN2,AP2A2,SPOP,MARCH4,OGT,PI16,SUGT1P4-STRA6LP-CCDC180,CDK10,PRX,ARRB1,CDK13,MARCH3,ATP1A2,ATP2B2,ATP2B3,SLC2A11,N4BP2L1,MPDZ,ARHGEF7,C1QC,CACNA1G,DIRAS1,KALRN,TRIM41,RUNX1T1,PRC1,INA,P2RX6,ENTPD2,NUMBL,CFL2,TAOK2,SLC22A6,PPT2,TPP1,FADS2,DNAJB5,CNTN1,COL4A5,COL9A2,ACBD5,CP,C1QL2,CTH,PUM1,ST18,ARHGAP32,CENPL,SPOCK2,IP6K1,GIT2,DBN1,DCTN1,ZEB2,PLEKHM1,C2CD2L,GSDME,DDX46,POM121,KIF19,DLG4,HS3ST4,DMPK,DPP6,DYRK1A,ABCC9,USH1C,PHC2,FCF1,EFNA3,APH1A,MBNL2,SORBS3,C3orf18,TMEM35A,OLIG2,RABEPK,SRRM1,EYA1,TAOK3,ZNF589,SPSB4,FGR,TMEM107,PRELID3A,GALC,B4GALNT1,IQGAP2,GAP43,SRCAP,HEPN1,RUNDC3A,RNPS1,GLI2,TNRC6A,GLUL,GNAS,TDRKH,STMN2,GRM7,CLASRP,RABL2A,FAM222A,ATXN2L,SMAP1,RAB41,LRRC25,RBPJ,USP54,IGSF1,LRRTM1,KCNA2,KCNJ3,KCNJ10,KIF5A,L1CAM,LAMP2,INSYN2,HECTD2,ZFYVE27,MAT2A,MEIS2,ERICH3,GIT1,MYO7A,RTL5,NF1,NRGN,IGSF11,CDK18,PDE2A,PLTP,MAPKAP1,SH3KBP1,POU3F2,PKN2,MAPK3,KLK6,SIDT1,MDGA2,ZSCAN32,PTPRH,CCDC40,ROGDI,FEZF2,ZDHHC4,KCTD17,SEC61A2,RPE,NEK11,FOXRED2,SCN2A,SELL,CASC3,ITSN1,SH3GL2,FAM81A,NAPB,SNCB,WDTC1,MYT1L,ZSWIM8,SPTB,IQSEC2,SEPT3,SYN1,CAMTA1,PCDHB15,SLC19A3,ARHGAP9,TPM4,PRMT8,TRH,PORCN,CLDND1,GPR158-AS1,ZSCAN26,ANKS1B,PRTFDC1,HPS4,LINC00632,PCBP4,ST7,NHSL1" MicroRNA hsa-miR-1909*:mirSVR_lowEffct hsa-miR-1909*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.39E-72 5.27E-68 4.00E-71 3.69E-70 209 976 "ACTN2,SLITRK1,ADCY6,PLEKHH1,KCTD16,OSBPL1A,C1QTNF3,ARHGAP20,SYT13,CDC42BPA,VAT1L,CDK13,CAPRIN2,ATM,SLC2A11,DPY19L3,TTLL9,ADAM15,ADGRB2,MIR9-3HG,DNAJC27-AS1,DCAF5,NRP2,SYNJ2,MTMR2,AP1M1,SGCE,CDK5R2,CACNB4,NGB,CAPN3,LDB2,CCKBR,CD81,SEPT7,ADGRG1,ASIC3,NDST3,PPT2,STOML1,FAM149A,COL9A1,ABI3BP,ZNF385A,CREB5,CS,RGS6,CSNK1E,OSBPL3,ATRNL1,SDC3,FAM131B,CX3CR1,MYADM,TOMM20,ARMCX4,ZNF804A,ZEB2,CEP170,POM121,SNAP91,G3BP2,WDR20,CCDC3,CD99L2,DMTF1,DNAJB6,ABCC5,DNM1L,ABCC9,PHC2,YAF2,IRAK4,SEZ6,CEND1,F3,WAC,CACNG3,ACSL4,ST3GAL6,TOMM40L,FCGRT,FER,FGFR3,BAIAP2,FLT1,SLC37A3,KBTBD12,ADGRA1,GAD1,ATP8A2,GFER,RND1,MAP7D2,TMEM121B,PCLO,GRM7,LINC01551,SLC2A6,ZHX1,AGBL5,TLX1,C9orf129,SHISA6,ICA1,MSL1,IL6R,TMEM240,KCNJ11,KIT,LIMS1,CLEC18A,MAP4,MBD1,MBP,MDFI,KITLG,SCAMP5,AFDN,STK32C,SCG3,MTR,C10orf105,LYRM9,MYO7A,ZC3H12B,SFR1,CNOT4,SLC11A2,OPA1,OPHN1,ZNF827,SNTG1,DPY19L2P2,PCSK5,PDYN,GPR85,NLGN3,PIK3R1,PLXNB3,ING3,TNPO2,SH3KBP1,PTPA,KANSL1,PRODH,CNNM2,NDUFS7,ZIK1,PTPRO,FAT4,RBBP8,GTDC1,UBR7,RAVER2,ACER3,KCNIP3,SBF1,CSRNP3,DRAXIN,ATXN2,ATXN7,HOGA1,LINC00461,SLA,SLC1A3,URGCP,WDR47,LRRC55,ZNF430,SLC8A1,SLC8A3,RIMS1,SNRPN,TNIK,DDN,SRPK2,CLASP2,ZC4H2,ACSBG1,SYT1,ANKRD28,FBXW11,SYNE1,TGFBR3,HHIP,CDH22,TLR4,PIK3R5,TPD52L2,RGMB,TRIO,AMOT,UGT8,OSBP2,CCDC14,ZNF711,ATP6V0E2,SPHK2,POLR3H,UPF3A,PRDM2,SEMA3B,C12orf4,FBXO36,NLRP3,ZNF248,RNF170,SLC39A12" MicroRNA hsa-miR-7:mirSVR_highEffct hsa-miR-7:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.34E-71 7.52E-68 5.71E-71 5.26E-70 218 1058 "SDE2,CSMD3,ADD2,KIAA1211,SEMA6A,CARNS1,CCDC146,PHF12,GPAM,TNRC6C,ARHGAP5,LINC00173,CAPRIN2,NCOA1,ASTN1,ATP1B3,ATP2B2,DPY19L3,ADAM23,ST3GAL5,SYNJ2,SCAPER,SGCE,CA8,SLC25A14,SYT6,CD86,LGI1,MAGI1,FOXN3,MS4A7,CNOT8,NDST3,IGFBP7-AS1,TPP1,NIPBL,IGLON5,CNN3,ARMC8,AHCTF1,TCEAL2,HS3ST5,CPS1,CLIP3,ATRNL1,CMTM5,CTNND1,NRSN1,EDRF1,CYBB,BOC,AIF1L,SPATA2,ZEB2,MAGI2,SV2B,DPYSL2,DTNA,ABCC5,ABCC9,SEZ6L2,ATL1,FAM13A,PHF20L1,EGFR,EGR3,ENO2,ERBB4,MRPL37,NRN1,WAC,ACSL4,RACK1,CEP78,FCGR3A,TOMM40L,GORAB,FGF13,IP6K2,SGIP1,SLC37A3,POMT1,SMC2,ATP2C1,STAU2,PNMA2,ZNF512,PHYHIPL,GABRA1,GABRA2,GAD1,DISC1,WASF3,GCNT2,SULT1C4,GFER,GGT7,GLS,GOLGB1,GRIN2C,KAT7,DHX35,USP54,INPP5B,KCNMA1,HECTD2,PIK3AP1,ADAM11,MOG,CTNNA3,MYCN,LRIT2,HCN1,NTRK2,OCRL,CHAMP1,P2RX7,PAX6,PBX1,PCMT1,PDE4B,PDE4D,A2ML1,ST8SIA5,MAPKAP1,STRN3,SPATA6,CRLS1,PRKCB,MAPK4,CNTLN,PTK2,RAB5B,FAM66C,FAM184A,OXR1,ARID4A,SLC6A15,ERI2,CARF,RPL15,ACER3,MEG3,NCBP3,SEMA6D,SATB1,IL17RB,SH3BGR,ITSN1,KIF16B,HKDC1,AMBRA1,FHOD3,R3HDM2,PAAF1,WDR47,SLC12A4,ELMO2,BTBD7,SPHKAP,TET1,SLIT1,NAXD,RCOR3,ANKRD36,SNCA,LMBRD1,TMCC1,MYO16,ZC3H13,KIF1B,TAB2,PBLD,CLASP2,NXT2,ZSCAN29,ZC3H4,VAMP1,SYT1,ASTN2,TACR1,ANKRD12,ROBO3,ANO4,TCF12,SYNE1,PCDHB15,ARHGEF12,FAM200B,ZNF106,CDH22,ASXL3,TLR4,FAM124A,SYNPO2,METTL3,SMUG1,RUNDC3B,TRO,PPIL6,RUSC1,RPL7L1,AMOT,UGT8,FLRT2,WIPF1,WNT7A,KCNT2,AGMO,FMN2,ZBTB16,EMSY,STOX2,GAL3ST3,MVB12B,RGS7BP,ST7,PHTF2" MicroRNA hsa-miR-4255:mirSVR_highEffct hsa-miR-4255:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-71 1.04E-67 7.88E-71 7.25E-70 193 842 "DSCAML1,CDC7,PWWP2A,PTCHD1,ADRB2,SLC44A5,TAOK1,C1QTNF3,ALAD,SEMA6A,AMPH,LRCH2,MAP4K3,APC,AQP4,PPP4R4,ARHGAP5,CAPRIN2,ASPH,RASL11B,ATP2B1,ARHGEF7,JAZF1,CANX,SLC25A14,SPAG9,CLDN10,ARHGEF2,CDC27,CHN2,CASC2,TJP2,HECTD1,TMEM155,FAM149A,BAG4,IGDCC3,CP,CHD1L,FAM171B,C2CD2,GDA,MICAL2,SIPA1L1,HDAC9,GPRASP1,C8orf34,HEPH,CEP170,ALKBH8,SACS,USP3,CPEB2,DPH1,ABCC9,WDPCP,ANKRD46,MBNL2,KMT5B,EIF5,PLEKHA1,EPB41L2,EPHA5,SH3YL1,FCGR1A,FDFT1,POLR1B,SUCO,MEX3B,FOXM1,FLT1,ANKFY1,SLC37A3,HVCN1,NPTN,ATP6V1H,HHIPL1,OGA,FYB1,GALC,GCNT2,CRCP,TCERG1,DBF4,TOX3,CBX1,CECR2,RAPGEF4,GRIA1,TMEM25,GSTT2,MFSD2A,LINC01551,PSIP1,HPS5,ZHX1,LINC01102,GABARAPL2,HNMT,ZIC5,RBPJ,DOCK7,ITPKB,KCNN2,SYTL4,MARK3,MBNL1,LRP1B,MOG,MTTP,MTR,NAP1L3,NF1,NKX2-2,GPR88,OXTR,PCSK1,PDE4B,PDGFRA,BEST3,PFKP,A2ML1,RETREG1,PCDH18,HMGCLL1,NXPH1,PIGG,PTX3,CEP97,ACSS3,OXR1,ARID4A,GTDC1,RGS12,RIC8B,CYB561D1,ELP2,ACER3,NCBP3,AMER2,SCN2A,SCP2,NTNG1,R3HDM2,CNKSR2,RUFY2,CCDC88A,SLC12A2,SMARCE1,LIMCH1,UNC80,PDZD2,BDP1,SP2,IDI2-AS1,ZC3H13,TAB2,CLSTN2,LARP4,LRRC4,ADHFE1,CAMTA1,FBXW11,TCEA1,TRIM2,AKTIP,THBS4,ERCC6L2,BEX4,TPM1,TPM3,STXBP4,HIRA,UBE3A,UGT8,NSD2,KLC2,XPO1,SLC47A2,ZBTB14,CELF4,PLPPR5,CSDE1,PCDH15,WNK3,UBE3B,HNRNPA3,ACTR3B,SSPN,KLHDC1,FRMD6,IFT88,SLC4A10" MicroRNA hsa-miR-425:mirSVR_highEffct hsa-miR-425:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.95E-71 1.09E-67 8.28E-71 7.63E-70 197 876 "NCKAP5,ADCY6,BRAP,SORCS1,GRAMD1B,ZNF608,KLHL13,CC2D2A,AMPH,ANK3,LCORL,BCAS1,API5,TMEM263,ASPH,ATP1B3,N4BP2L1,ADGRB3,MPDZ,BTK,SGCE,C5,CACNA1D,KALRN,CANX,HIP1R,SPAG9,CDC27,LGI1,CFL2,SRSF11,B4GALT6,TJP2,QKI,TMEM155,CNN3,ARHGEF6,ARMC8,WHRN,MYRIP,ZFP28,CLOCK,CREM,RBM39,CS,LRIG1,PHACTR3,GREB1,CYBB,DOCK4,GPRASP1,RIPOR2,DGKG,KIAA0319,RHOBTB1,SNAP91,SV2B,EXOG,CDON,CPEB2,DYRK1A,GOLT1B,EDIL3,FAM135B,EDNRA,KMT5B,PCOLCE2,KCNMB2,DNAJC27,SH3YL1,ZSCAN30,GTF2IRD2,SUCO,SYNCRIP,ANKFY1,SGIP1,GABRB3,CAB39,GAD1,GALC,KIAA1841,COPS8,GLS,WDFY3-AS2,PCLO,ATP2B1-AS1,RNF165,ARHGAP36,ELOVL5,HNMT,SHISA6,HTR5A,IGF1,C5orf24,USP54,IL11RA,ZNF678,ITPKB,SLC35G1,STXBP5,STMN1,FGFBP3,MARK1,MBD1,SYT9,LRP1B,MEF2C,MEIS1,MIA2,PPM1L,GIT1,MSR1,CTNNA3,ZNF862,NCF2,NDUFA5,NELL1,CNOT4,LRIT2,NPPA,NTRK3,NUCB2,OCRL,SNTG1,PCMT1,PRTG,PLCB2,PLCL1,PURG,TRHDE,ING3,MINDY2,CRLS1,PRKCZ,MAPK9,LRRC49,MDGA2,QRICH1,CNTLN,PTCH1,BDNF-AS,PTPRN2,PEX5,ZNF844,RGS4,MRPS18A,NUDT11,SETD5,RPL15,FBXW7,BAALC,LRRK2,ELMOD1,GALNT10,PPM1E,CHD9,PPP4R3A,SLC6A1,SLC6A11,SLC8A3,LIMCH1,SNAP25,MBD5,SNRPN,PDZRN3,ZNF423,ZC3H13,CLSTN2,SSTR2,NKAIN2,NXT2,CEP68,AJAP1,VPS13A,SYN2,VWA3A,SATB2,TCF7,RPGRIP1L,DICER1,BHLHB9,BEX4,TNS1,TRO,STXBP4,TSN,VLDLR,WIPF1,KCNT2,EML6,PRDM8,PARP11,KAT6A,ADAMTSL3,IFT88,SLC4A10,FAM198A" MicroRNA hsa-miR-629:mirSVR_highEffct hsa-miR-629:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-71 1.40E-67 1.06E-70 9.73E-70 184 769 "RALGAPA1,SYS1,SORCS1,ERMN,SNX30,DPY19L2P4,MTUS1,GPR158,KLHL13,OSBPL8,ALAD,ALCAM,USP28,KCNAB2,TNRC6C,SPTBN4,ZFYVE28,CADPS,ASPH,INSYN2B,ATM,ATP6V1G2,RIPK1,SEC11C,MTMR2,BSN,CACNA1D,KALRN,CD86,CDH10,DIS3L,SRSF11,SLC22A6,TJP2,CNTN1,IQCK,COL4A5,LETMD1,GAL3ST1,NCOR1,GDA,CSF2RA,SUSD5,ATRNL1,APPL1,LONRF1,DGKB,KIAA0753,MAGI2,SMG7,WDR20,KBTBD11,NR1D2,CPEB2,EDNRA,TMTC1,SUGP2,EIF1,KCNMB2,EFS,ABCA8,WAC,FGF1,POLK,UBE2E3,AGAP3,ATP2C1,STAU2,GABRB3,GAD2,GAP43,C15orf41,ALDH1L1,ADAM28,CSDC2,RNPS1,SPIN1,GLUL,LUZP2,GP1BB,TDRKH,PCLO,PLCD4,GRIN2D,NR3C1,GRM7,KAT7,MUM1,RASSF8,HNMT,ZDHHC15,SMAP1,ZIC5,RBPJ,USP54,IL11RA,KCNK2,STXBP5,PAXBP1,SYT9,MID1,BLOC1S2,MTTP,P2RY13,NCAM1,NTRK3,GPR88,PAX6,DPY19L2P2,ENPP2,PIK3C2A,FAM218A,SNX10,MTRF1L,STRN3,MED1,PPM1B,MAPK10,MASP1,SYTL2,PSMD13,PTPRD,PPP2R3C,ZMAT4,RFX4,ARHGEF10L,RNASEL,KLHDC8A,BAALC,ATAT1,KCNIP3,CCDC112,FAM102A,MYO18A,FHOD3,ANKRD6,FAM81A,BTBD3,WDR47,SLC8A1,SLC14A1,ZFP1,RCOR3,RIMS1,UNC80,SOX5,HECW1,NKAIN2,NCDN,ELOVL4,CEP68,SULF2,GANAB,NECAB1,FGD4,ADAMTS17,COBL,TACR1,TCF4,TCF7L2,RALYL,PCDHB9,SLC19A3,USP32P1,GPRIN3,TMOD1,TMPO,C5orf64,WBP2,TRH,PLEKHH2,MEAF6,ZNF781,RICTOR,ZIC2,ZNF70,PLPP4,EML6,LAMP5,FZD3,MARCH8,PHTF2,NETO2,NETO1" MicroRNA hsa-miR-514b-3p:mirSVR_highEffct hsa-miR-514b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.33E-71 1.87E-67 1.41E-70 1.30E-69 181 746 "KCNH8,ERMN,PWWP2A,AMER3,CDC14B,MARK4,NCOA1,BACH1,ADGRB3,SEC11C,JAZF1,CLGN,CHN2,TAOK2,RAB28,NRXN3,FAM149A,BTF3L4,MYRIP,TRIM69,CSNK1G3,FAM169A,CFAP61,HDAC9,DGKB,MAGI2,PLPPR4,RABGAP1L,NR1D2,ABI1,GNE,ABCC9,GOLT1B,E2F6,EGFR,ELAVL4,PCOLCE2,VPS13B,EPS8,AMZ2,FABP7,SUCO,CAP2,SYNCRIP,FLT1,SLC37A3,ARFGAP2,DACH2,NSG1,PHYHIPL,GAD2,B4GALNT1,SULT1C4,GK,GLI2,INSM2,DCLK2,LPAR4,GRIA2,GRIK2,NR3C1,GRM8,KLF12,HNMT,ZNF491,CELF5,FAAP20,IDH3B,USP54,LRRTM3,ITGAM,JAK1,SLC35G1,OLFM3,KCNB1,KCNK2,KLC1,LIG4,HECTD2,NCOA7,MATN3,MEIS2,POC1B,AFDN,SESN3,ADAM22,RSPO2,MXI1,IDNK,NNAT,PCSK5,PDE3B,SSH1,PLCL1,STRN3,SPATA6,TATDN3,SLC26A11,HYDIN,BDNF-AS,PTHLH,TMEM260,EML5,PTPRG,PTPRZ1,RAB3A,NWD1,ENOX1,KHDRBS2,RFX3,SLC25A36,TMLHE,CCDC102B,BAALC,ZC3H14,RTN1,SCN3A,LRRTM4,SCN8A,PEAR1,TRIM46,NTNG1,FNDC3A,SEC31A,ZNF365,SEPHS1,NAPB,NAXD,ZNF667,TTC17,UNC80,SON,SPP1,ERC1,NPAS3,ERBIN,ZSCAN29,SYT11,ARHGEF9,VPS13A,C12orf76,TAC1,TBCEL,EHBP1,SIN3B,TCF12,WASHC4,USP22,SZT2,PCDHB6,TEK,ITGB3BP,CDH22,NACC2,C5orf64,TPM1,ZNF346,METTL3,TRPC3,ANO5,TTTY15,CADM1,EIF4ENIF1,UGT8,RBFOX3,PORCN,ETNPPL,ZNF142,FSTL5,EML6,PLPPR5,SYNC,SLC30A4,MFF,MDH1B,NAV3,KCNAB1,MVB12B,HNRNPA3,RNF170,NETO2" MicroRNA hsa-miR-26b-5p:TargetScan hsa-miR-26b-5p TargetScan 3.33E-71 1.87E-67 1.41E-70 1.30E-69 181 746 "PLEKHH1,PWWP2A,PTCHD1,INTS2,KCTD16,ANK2,EP400,APC,APP,CDK13,CCAR2,DDX3Y,INSYN2B,ATP1A2,DOCK11,ADAM23,BID,GPR146,CDK5R1,DST,FUBP1,NIPA1,CACNA2D1,CACNB4,CAMK2A,MAP7,CD38,CDH2,DCLK1,KMT2C,KIAA1549L,DNAJB5,NIPBL,CNR1,AKAP7,COL9A1,ACBD5,NRG2,HAPLN1,CHD5,FAM169A,ERC2,PLCXD3,CTH,GREB1,CTNND2,GPSM1,PYGO1,DOCK4,MATR3,DAPK1,PITPNC1,ARMCX2,JAKMIP2,MFAP3L,C2CD2L,SACS,G3BP2,DLG4,DMD,CPEB2,DYRK1A,PHF20L1,ABI2,EIF4G2,EIF5,ELAVL2,ELAVL3,RGS17,PAN3,EPHA5,ERBB4,RCSD1,MED12L,PRKAG2,CAMSAP1,MEX3B,FAM49B,CELF1,FUT9,MPP6,GABRA4,GAD2,RAPGEF6,NEK6,FAXC,MSTN,GPR12,GRB10,DIDO1,LINGO1,HAS2,MIER3,HTR2A,IGF1,CDH20,KCNK1,KCNN3,KPNA5,LIFR,LIMS1,MAP2,MARK1,MAT2A,CHIC1,MEF2C,MITF,MMP16,CD200,BLOC1S2,MXI1,MYO9A,NCAM2,NOVA1,DDR2,P2RY1,PDE3B,PDE4B,PDE4D,PFKFB2,PFKFB3,FAM98B,PIK3C2A,CCSER2,GPSM2,PLCL1,PCDH18,FA2H,PPP2R2B,PPP3CB,CEP41,GRAMD1C,PTPN13,PTPRD,MARCH1,ENOX1,FIGN,RFX3,RGS4,NUDT11,PRR5L,ACER3,RIMKLA,RPS6KA2,RTN1,SALL1,ATXN7,FNIP1,GALNT10,MRAS,HSPA4L,CPEB3,FBXO11,NLGN1,FAM214B,BTBD7,CPEB4,EPC1,KIF21B,LHFPL4,ARHGAP26,CLASP2,LARP4,MPRIP,PLCB1,KAZN,CAMSAP2,FAM208A,PSD3,ARHGEF12,GPR161,NACC2,DDHD1,DCBLD1,AMOT,ANKS1B,PHTF2,RSPRY1,NHSL1,NETO1,GAN" MicroRNA hsa-miR-26a-5p:TargetScan hsa-miR-26a-5p TargetScan 3.33E-71 1.87E-67 1.41E-70 1.30E-69 181 746 "PLEKHH1,PWWP2A,PTCHD1,INTS2,KCTD16,ANK2,EP400,APC,APP,CDK13,CCAR2,DDX3Y,INSYN2B,ATP1A2,DOCK11,ADAM23,BID,GPR146,CDK5R1,DST,FUBP1,NIPA1,CACNA2D1,CACNB4,CAMK2A,MAP7,CD38,CDH2,DCLK1,KMT2C,KIAA1549L,DNAJB5,NIPBL,CNR1,AKAP7,COL9A1,ACBD5,NRG2,HAPLN1,CHD5,FAM169A,ERC2,PLCXD3,CTH,GREB1,CTNND2,GPSM1,PYGO1,DOCK4,MATR3,DAPK1,PITPNC1,ARMCX2,JAKMIP2,MFAP3L,C2CD2L,SACS,G3BP2,DLG4,DMD,CPEB2,DYRK1A,PHF20L1,ABI2,EIF4G2,EIF5,ELAVL2,ELAVL3,RGS17,PAN3,EPHA5,ERBB4,RCSD1,MED12L,PRKAG2,CAMSAP1,MEX3B,FAM49B,CELF1,FUT9,MPP6,GABRA4,GAD2,RAPGEF6,NEK6,FAXC,MSTN,GPR12,GRB10,DIDO1,LINGO1,HAS2,MIER3,HTR2A,IGF1,CDH20,KCNK1,KCNN3,KPNA5,LIFR,LIMS1,MAP2,MARK1,MAT2A,CHIC1,MEF2C,MITF,MMP16,CD200,BLOC1S2,MXI1,MYO9A,NCAM2,NOVA1,DDR2,P2RY1,PDE3B,PDE4B,PDE4D,PFKFB2,PFKFB3,FAM98B,PIK3C2A,CCSER2,GPSM2,PLCL1,PCDH18,FA2H,PPP2R2B,PPP3CB,CEP41,GRAMD1C,PTPN13,PTPRD,MARCH1,ENOX1,FIGN,RFX3,RGS4,NUDT11,PRR5L,ACER3,RIMKLA,RPS6KA2,RTN1,SALL1,ATXN7,FNIP1,GALNT10,MRAS,HSPA4L,CPEB3,FBXO11,NLGN1,FAM214B,BTBD7,CPEB4,EPC1,KIF21B,LHFPL4,ARHGAP26,CLASP2,LARP4,MPRIP,PLCB1,KAZN,CAMSAP2,FAM208A,PSD3,ARHGEF12,GPR161,NACC2,DDHD1,DCBLD1,AMOT,ANKS1B,PHTF2,RSPRY1,NHSL1,NETO1,GAN" MicroRNA hsa-miR-204:PITA hsa-miR-204:PITA_TOP PITA 5.46E-71 3.07E-67 2.31E-70 2.13E-69 138 431 "TTYH1,KCNH8,ADCY6,KLHL13,ZNF578,SEMA6A,OGT,TMEM263,ARHGAP5,DDX3Y,ATP2B1,BCL2L2,CDH2,CCPG1,FOXN3,SOCS6,CHN2,NIPBL,PCYT1B,ACBD5,ZNF521,RBM39,CREB5,CHD5,GAPVD1,DCAF8,HDAC4,LONRF1,TM9SF4,RHOBTB1,SNAP91,FAM107B,DLG4,DNM2,SLC12A6,PDCD6IP,DYRK1A,FRY,EFNB3,APH1A,ELAVL3,EPHA5,EPHB1,RPS6KC1,ACSL4,SCML2,SUCO,AGAP2,SGIP1,SLC37A3,NBEA,KHDRBS3,MEGF10,GABRB3,GABRG2,BRPF3,ARFIP1,GGT7,PPARGC1A,TOX3,GPM6A,TPPP,GRM1,MAP4K5,FRMD5,KLF12,MIER3,ELOVL5,SCRT2,INSM1,JAK2,KCNA1,KCNC2,KCNMA1,NCOA7,MBNL1,MEF2C,MGAT3,KITLG,SAMD5,MXI1,NOVA1,NPTX1,OPCML,PCDH9,PRTG,RETREG1,XRN1,PRRX1,POU3F2,SNRK,PTCH1,PTPRD,PTX3,PID1,TMEM255A,USP47,ARID4A,SEC61A2,ZFHX4,FBXW7,LGR4,CLIP1,ATXN1,SCN2A,FNIP1,PPM1E,KIF16B,ST3GAL3,YPEL4,TRIM67,CPEB4,RCOR3,MYT1L,ZCCHC24,SOX11,PEG10,ZNF423,LMO3,SRPK2,SMOC1,ERBIN,RGL1,ANKRD12,CAMTA1,TCF4,SATB2,TCF12,SIRT1,ZFP91,RBFOX2,FLRT2,TMEM237,PRDM2,PRDM10,WNK3,RGS7BP,ST7" MicroRNA hsa-miR-211:PITA hsa-miR-211:PITA_TOP PITA 5.46E-71 3.07E-67 2.31E-70 2.13E-69 138 431 "TTYH1,KCNH8,ADCY6,KLHL13,ZNF578,SEMA6A,OGT,TMEM263,ARHGAP5,DDX3Y,ATP2B1,BCL2L2,CDH2,CCPG1,FOXN3,SOCS6,CHN2,NIPBL,PCYT1B,ACBD5,ZNF521,RBM39,CREB5,CHD5,GAPVD1,DCAF8,HDAC4,LONRF1,TM9SF4,RHOBTB1,SNAP91,FAM107B,DLG4,DNM2,SLC12A6,PDCD6IP,DYRK1A,FRY,EFNB3,APH1A,ELAVL3,EPHA5,EPHB1,RPS6KC1,ACSL4,SCML2,SUCO,AGAP2,SGIP1,SLC37A3,NBEA,KHDRBS3,MEGF10,GABRB3,GABRG2,BRPF3,ARFIP1,GGT7,PPARGC1A,TOX3,GPM6A,TPPP,GRM1,MAP4K5,FRMD5,KLF12,MIER3,ELOVL5,SCRT2,INSM1,JAK2,KCNA1,KCNC2,KCNMA1,NCOA7,MBNL1,MEF2C,MGAT3,KITLG,SAMD5,MXI1,NOVA1,NPTX1,OPCML,PCDH9,PRTG,RETREG1,XRN1,PRRX1,POU3F2,SNRK,PTCH1,PTPRD,PTX3,PID1,TMEM255A,USP47,ARID4A,SEC61A2,ZFHX4,FBXW7,LGR4,CLIP1,ATXN1,SCN2A,FNIP1,PPM1E,KIF16B,ST3GAL3,YPEL4,TRIM67,CPEB4,RCOR3,MYT1L,ZCCHC24,SOX11,PEG10,ZNF423,LMO3,SRPK2,SMOC1,ERBIN,RGL1,ANKRD12,CAMTA1,TCF4,SATB2,TCF12,SIRT1,ZFP91,RBFOX2,FLRT2,TMEM237,PRDM2,PRDM10,WNK3,RGS7BP,ST7" MicroRNA hsa-miR-3169:mirSVR_highEffct hsa-miR-3169:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.86E-71 3.29E-67 2.48E-70 2.29E-69 172 677 "RBM10,ADD1,AXIN2,PTCHD1,PCDH19,RTL9,TAOK1,ARHGAP20,PCDH10,OGT,MYH7B,USP28,PPFIA1,SUGT1P4-STRA6LP-CCDC180,ANXA7,ALS2,TMEM263,CADPS,ASPA,ZBTB10,NUMB,DDX3Y,ATP2A2,BACH1,DNAJC27-AS1,DCAF5,SYNJ1,ARHGEF7,THSD7A,PTBP2,CAST,PRC1,DLGAP1,NPIPA1,LHX2,CLCN3,COG1,RAB26,FHL5,SUMF2,CHD1L,CPS1,C2CD2,CREM,RNF14,CLIP3,SEC24C,ARHGEF10,ATRNL1,VCAN,PHF14,GREB1,NRSN1,DOCK4,RIPOR2,ARHGAP24,TOX,LIN54,SMG7,KBTBD11,DMTF1,DPP6,DYRK1A,AASDH,ELAVL3,DCTN4,EPB41L2,ADGRV1,ACSL4,ZNF589,SPSB4,PRKAG2,HPCAL4,SGIP1,TMEM175,JKAMP,KHDRBS3,B3GAT1,AP4B1,CAB39,SULT1C4,GGTA1P,TDRKH,GRIA2,NR3C1,KAT7,HPS5,NXPH2,VSIG4,HSP90AA1,SOWAHA,RBPJ,IL11RA,KIF5A,FGFBP3,NCOA7,MAT2A,MATN3,MDM4,MEF2C,MMP16,BCO1,MXI1,MYO9A,NDUFA5,NF1,CNOT4,PCMT1,PDE2A,PDE4D,PDGFRA,PDYN,ZNF655,ING3,MTMR10,ARID4A,CRTAC1,GTDC1,FIGN,ZDHHC4,NUDT11,TMLHE,YY1AP1,LRRK2,KCNIP3,KCNIP1,AP1AR,SATB1,CSRNP3,SCN2A,SCN3A,SCP2,SEC14L1,FERMT1,DOCK10,SHC4,FBXO11,FNDC3A,PAAF1,SEPHS1,CCDC88A,ATF7IP,SORCS3,RCOR3,TMCC1,MYO16,STAU1,RGL1,FGD4,COBL,UNC5D,CUX2,RPGRIP1L,DOCK9,PCDHA5,TGFBR3,GZF1,ERCC6L2,BEX4,TPM1,TPM3,C9orf85,TRPC3,BEST1,ZNF711,ZFAND5,LRP8,FIP1L1,MPPE1,PAK5,FXR1,SENP7" MicroRNA hsa-miR-376a*:mirSVR_highEffct hsa-miR-376a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.29E-71 3.53E-67 2.66E-70 2.45E-69 209 986 "NBAT1,SLITRK1,GALNT13,ADD3,RNF150,KIDINS220,MTUS1,TXNDC16,SPARCL1,DPP10,PPFIA1,GPAM,PPP4R4,IGDCC4,SPTBN4,ARHGAP5,MARK4,NUMB,N4BP2L1,MPDZ,SGCE,CACNA1G,OSGIN2,CACNB2,KALRN,PTBP2,CAST,KRIT1,DGKI,LRBA,CDC27,LRRFIP1,CASC2,NRXN3,PLAA,TMEM184B,MAP4K4,AKAP6,COL9A2,ABI3BP,SLC32A1,FEZ1,SUSD5,PHF14,CTH,KIAA0586,C8orf34,CEP170,RHOBTB1,SACS,G3BP2,WDR20,USP3,DMTF1,GNE,DTNA,DYRK1A,ABCC5,HIPK3,FRY,YAF2,PHF20L1,TENM1,RABEPK,DENND4A,FER,FGFR1,CAMSAP1,SEC23B,CAP2,UFM1,TPK1,ZNF605,CELF1,STAU2,NRG3,MEGF11,MEGF10,GABRA2,HRASLS5,B4GALNT1,DNER,PPARGC1A,DBF4,SPIN1,KIAA1958,ADGRA3,PRUNE2,STON1,ATE1,GRM1,LINC00839,MFSD2A,PSIP1,GUCY1B1,ARHGAP19,TNFAIP8L3,ELOVL5,HMX1,CFAP126,HSPA1L,RBPJ,USP54,KCNC2,KCNK1,KIF5C,KPNA5,MAP6,LYPLAL1,AQP11,MEIS1,MIA2,MSR1,NAP1L3,NDP,NINJ2,NRCAM,SLC10A4,GPR85,OLA1,PIK3C2A,ZNF655,PLP1,ING3,HYDIN,MDGA2,PLPPR1,PTHLH,PTN,ZIK1,PTPRH,RASGRF1,RDX,PBRM1,SUGCT,CARF,GSTCD,CCDC102B,RPE,NEK11,BAALC,ATP8B4,CLIP1,ZNF568,LRFN5,SCN2A,FAM19A1,LINC00461,FNIP1,KIF16B,CPEB3,SHC4,CHD9,CNKSR2,FAM81A,RUFY2,SEPHS1,SLC9A5,TET1,SMARCE1,ANKRD36,MBD5,UNC80,FNBP1,SP4,KDM4C,SPART,CAMTA2,DIP2A,SULF2,VPS13A,C3orf70,TACC1,MTCL1,DDHD2,CAMSAP2,ADGRL3,ZEB1,RPGRIP1L,TCF12,SYNE1,PCDHB7,PUM2,SIRT1,AP4E1,TIAM1,ZFP91,BEX4,C5orf64,NPL,TRPC1,ZMYND8,TMEFF2,RPL7L1,UGT8,ZNF711,ZNF28,ANKS1B,SYNC,SCG2,FIP1L1,SLC17A6,EPM2A,RGS7BP,AMN1,RTN4,PHTF2,TTC7A,GAN" MicroRNA hsa-miR-488*:mirSVR_highEffct hsa-miR-488*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.57E-71 4.25E-67 3.20E-70 2.95E-69 184 774 "ABAT,ASIC2,CLK4,MTUS1,BCAR3,FAM135A,ANK2,SUGT1P4-STRA6LP-CCDC180,EPB41L5,MIER1,TMEM263,CDK13,BRINP2,ZBTB10,NCOA1,ATP1A1,ALDH7A1,CADM3,ADGRB3,DST,CALB1,CAST,C1orf52,CDC27,CDH10,DLGAP1,CDR1,NOG,CHN2,FBXO7,MAP4K4,CNN3,ARMC8,SLC4A8,ABI3BP,BAG4,CP,CHD1L,FAM171B,CREM,ANKRD44,NRSN1,DOCK4,ZFYVE16,SCRN1,SPATA2,HEPH,ZNF582-AS1,DPP6,DTNA,ECM2,EBF1,EDNRB,TMEM132E,RCAN2,EPHA5,EZH1,WAC,EFEMP1,RACK1,TOMM40L,FDFT1,GORAB,UBE2E3,C2orf88,USP16,ZNF512,CHL1,CAB39,ZMYND11,GLRB,GLS,CNDP1,LILRA2,GPR37,ADAMTS8,GRM7,RASSF8,GABARAPL2,HPCA,LRRC75A,HTR2A,MYLK2,USP54,IL6ST,NME9,KCNA2,KCND2,KCNK2,SYTL4,MARK1,MBNL1,POC1B,MTTP,LYRM9,NDUFA5,OTOGL,NFE2L2,NOVA1,SLC11A2,OXTR,PAK3,PBX1,CDK18,PDCD2,PDE1C,RETREG1,HMGCLL1,RC3H2,EXOSC10,PPARA,PPP2R5E,PKIA,MAPK9,GDPD2,SNRK,BDNF-AS,PTPRG,PTPRN2,C1orf109,SLC25A48,USP47,SH3TC2,SLC25A36,SETD5,TMLHE,ARMC5,GSTCD,ELP2,CCDC102B,FBXW7,ZC3H14,ATP8B4,PRR5L,CNTNAP3,ATXN7,FNIP1,MRAS,ZFP30,ITSN1,CPEB3,SHC4,CHD9,TET1,IFT122,ANKRD36,SNRPN,SON,SP4,KDM4C,C11orf87,NKAIN2,SS18,CEP68,TTBK2,FGD4,FAM208A,KLHL4,TCEA1,RPGRIP1L,WASHC4,SYNE1,ARHGEF12,SIK3,ITGB3BP,ASXL3,BHLHB9,FAM124A,TPM1,PLEKHH2,MEAF6,MKRN3,SPHK2,ZNF177,SH3GLB2,SYNC,MAP3K12,PRDM2,PRDM10,NAV3,PDSS2,FBXO36,ZNF248,NETO1" MicroRNA hsa-miR-1238:mirSVR_lowEffct hsa-miR-1238:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.25E-71 4.64E-67 3.49E-70 3.21E-69 216 1050 "SDE2,SYS1,ACTN1,CSMD2,KLRC4,BEND6,WDR35,ALCAM,AMPH,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,APBA2,APBB2,CACHD1,BCAS1,TMEM263,ZFYVE28,PLA2G4C,NCOA1,EIF4G3,ATP2A2,ATP2B2,N4BP2L1,SYNJ1,ST3GAL5,CACNB2,PTBP2,RUNX1T1,ENTPD6,CDO1,CCPG1,MS4A7,CLCN3,AKAP6,TBPL1,ZNF521,NRG2,CNRIP1,CREM,SIPA1L1,PITPNM3,GREB1,CFAP61,LIN54,IP6K1,DCC,YTHDC1,ZEB2,BLOC1S6,DDX46,HS3ST4,CDON,DMTF1,DTNA,TOM1,E2F5,GPR61,PHF20L1,MBNL2,ABI2,STX2,SPEG,CEND1,MRVI1,NSRP1,CACNG2,PRMT5,FER,FGF11,AMOTL2,NRG3,ZMAT1,STAG2,GABRA5,TRAF3IP2,RAPGEF6,ARPP21,C15orf41,ALDH1L1,NFU1,ADAM28,ZNF276,RND1,GLI2,TNRC6A,ZNF638,KIAA1958,DCLK2,LNX1,PRLHR,CCDC184,PCLO,STMN2,GRIA4,ADAMTS13,MAP4K5,UBE2QL1,ARHGAP36,AGBL5,IGF1,SCIN,IL6ST,IL12A,KCNN2,KPNA5,PAXBP1,MARK3,MBD1,MBNL1,LRP1B,MID1,FXYD7,IDNK,NEK1,NEUROD2,NFE2L2,NME4,NUCB2,IGSF11,GLIPR1L2,PDE4D,PDYN,SLC10A4,CDK14,KCTD15,JAKMIP1,PRRX1,SEPT4,NXPH1,PPP2R5E,PKIA,PRKCB,DCHS2,MASP1,WBP1L,PTK2,PXK,PTN,PTPRE,PID1,RASGRF1,KHDRBS2,REV3L,ERI2,GTDC1,RFX4,RGS12,SEC61A2,EXD2,RAVER2,ROBO2,FBXW7,TCP11L1,HSD11B1L,PRCD,SLC30A10,TRIM46,FOXRED1,RASA3,ITSN1,NLGN1,ANKRD6,PAAF1,SMTN,CDK5RAP3,ELMO2,BTBD7,ZFP1,CDK5RAP2,SNRPN,TRERF1,EMC1,MYCBP2,PEG10,SS18,TAC1,EXOC7,PDLIM2,EHBP1,TCF7,ZEB1,TCF12,SYNE1,PHF24,PCDHB3,USP32P1,GPRIN3,AP4E1,FBXL16,TIAM1,TMPO,KCTD2,TNR,TPM1,NPL,C9orf85,ZNF384,SMUG1,RUNDC3B,STXBP4,RFTN2,ZKSCAN5,EIF4ENIF1,PITPNB,ZIC2,CELF4,SMARCAD1,UPF3A,HRASLS,FAM13C,DOCK8,UBE3B,KAT6A,FXR1,SLC4A10" MicroRNA hsa-miR-32:PITA hsa-miR-32:PITA_TOP PITA 9.59E-71 5.39E-67 4.05E-70 3.73E-69 145 480 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-3126-3p:mirSVR_highEffct hsa-miR-3126-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-70 5.85E-67 4.39E-70 4.04E-69 166 633 "SYN3,ASIC2,ARID1A,ADD2,DPY19L2P4,KIAA1324,AK2,AMPD3,DDX3Y,TMEM108,ATM,ATP1B3,ATP2A2,ZNF582,N4BP2L1,DST,ARHGEF7,CASTOR3,MMD2,CACNA1E,TRIM41,MAP7,NFS1,ARHGEF1,CDC27,LGI1,DIS3L,ARMC8,SLC25A27,SLC35F1,CREM,ANKRD44,NCAN,PDE4DIP,FAM169A,DOCK4,TMEM170A,GIT2,YTHDC1,ALKBH8,DYNC1I1,DTNA,EDN1,FCF1,KLHL5,COPS4,ELAVL4,EPB41L2,DENND4A,TMEM74,NSRP1,CACNG3,KAT8,GORAB,FER,FGFR1,FOXG1,NBEA,SMC2,STAU2,GABRA2,TRAF3IP2,CAB39,KIAA1841,TCERG1,HPGDS,GPM6B,DIDO1,GRIA4,PLCD4,GRM8,ZHX1,NXPH3,VSIG4,HNMT,DHX35,IRF8,MSL1,KIF2A,KLC1,LAMP2,ZFYVE27,MAP2,MARK1,ZNF680,NRBP2,N6AMT1,MYO7A,P2RY13,NCAM2,NTRK2,NUCB2,IGSF11,OPHN1,PDE1A,PDGFRA,SERPINI1,EPB41L4B,POLR2F,DRAM2,MINDY2,MASP1,WBP1L,SNRK,EML5,PEX5,USP47,OXR1,SLC6A15,RFX3,ROBO1,PCMTD2,ATP8B4,GLDN,MEG3,RTKN,KCNIP2,SEMA6D,ITSN1,SLITRK3,ANKRD6,WDR37,ARHGEF40,SLC12A2,USP33,KDM4C,CDK19,TROVE2,SEPT8,VPS13A,SYT4,TACR1,DDHD2,DNMBP,SIN3B,SATB2,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,AP4E1,TMOD1,SEZ6L,PRMT8,ELP5,RPL7L1,TRIM9,LYPD6,CELF4,CA10,MFF,PRDM2,MPPE1,PLSCR4,UBE3B,PHTF2,JMJD1C,AP3B2,SENP7" MicroRNA hsa-miR-371-5p:mirSVR_highEffct hsa-miR-371-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.41E-70 7.91E-67 5.94E-70 5.47E-69 212 1017 "CCDC85A,SLC12A5,SORCS1,PTCHD1,KIDINS220,DPY19L2P4,HACE1,NME5,CC2D2A,FAM135A,CDC42BPA,PHF12,PKP4,PARG,ALS2,SHTN1,MIER1,ASGR1,ASPH,ATP2B1,SLC2A11,NOL4,SEC11C,NRP2,GPC2,PTBP2,CAMK2G,SLC25A14,VSTM2A,KRIT1,DGKI,MAGI1,CFL2,CHM,NDST3,RAB33A,CNGA3,COL9A1,BTF3L4,SLC4A8,MFSD4A,HS3ST5,CS,AATK,MICAL2,SOCS5,CST3,DZIP3,ST18,CYBB,DOCK4,FGFR1OP2,DGKB,TMEM170A,IP6K1,DBI,ZNF804A,BLOC1S6,SMG7,SNAP91,FAM107B,DMTF1,SLC25A18,EDN3,ANKRD46,HIPK3,MBNL2,ABI2,COPS4,CALCRL,RCAN2,EPHB1,SRRM1,TMEM74,PIPOX,RTN3,ACSL4,FKTN,GORAB,GTF2IRD2,SUCO,UFM1,PDLIM5,STAMBP,STAU2,GABRA3,ILDR2,RAPGEF6,MTHFD2,DISC1,KIAA1841,TUBGCP4,GLS,TNRC6A,GLUL,STARD3,KDM2B,PRRC2B,TDRKH,EML4,RAPGEF4,GRIA1,GRIA2,DIDO1,GRIA4,FAM19A2,SOX21,ZDHHC15,SMAP1,ZIC5,METTL21A,KIF5C,CYP27C1,KTN1,ZNF667-AS1,MAP4,MEIS1,SRSF12,AFDN,COL28A1,MYCN,MYO9A,NEUROD1,NTRK2,NUCB2,DPY19L2P2,PCDH8,CDK18,PRTG,BEST3,FTO,PLP1,PCDH18,CDIP1,EXOSC10,NXPH1,CRLS1,APTX,BDNF-AS,PTPRZ1,PEX2,TMEM255A,FAM184A,RAP1GAP,RADX,NUDT11,RNASEL,CCDC25,UEVLD,RPS6KA2,SCN2A,LRRTM4,FAM19A1,LINC00461,ITSN1,R3HDM2,PPP4R3A,KANSL3,CPEB4,IFT122,RIMS1,SNAP25,MBD5,CABCOCO1,USP33,SOX2,SOX3,MYCBP2,LMO3,C11orf87,SRPK2,NKAIN2,SS18,SYNE2,PLCB1,SYN2,TBCEL,ATMIN,SATB2,AZIN2,SYNE1,PCDHB7,PUM2,SIK3,TLR4,HEY2,R3HDM1,CSMD1,SEZ6L,TPD52L2,ZNF346,BCL2L13,BEST1,ZNF24,TRIM9,EML6,ANKS1B,DHX33,PRDM10,ADAMTS9,VPS35L,NAV3,AMN1,DOCK8,RTN4,UBE3B,FAM219B,NLRP3,RNF170,IFT88,RNF146,FAM198A" MicroRNA hsa-miR-924:mirSVR_highEffct hsa-miR-924:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.51E-70 8.48E-67 6.36E-70 5.85E-69 195 869 "ASIC1,EMILIN3,DSCAML1,ERMN,SPARCL1,SPOP,ABCD2,OGT,SUGT1P4-STRA6LP-CCDC180,APBA2,GPAM,TNRC6C,TMEM108,ATP2B3,MTMR9,ADAM23,DCAF5,DST,RUNX1T1,ZNF501,CLDN10,CD38,C1orf52,CDC42,LRRFIP1,TIGD7,CCPG1,SOCS6,JAM2,NDST3,NRXN1,ARMC8,FAM149A,LETMD1,AKAP5,RCHY1,ENTPD4,SNCAIP,TENM4,RGS6,CSF2RA,CTH,GREB1,CTNND1,ST18,CX3CR1,DOCK4,TCAF1,DCAF8,FRMPD4,DAPK1,EXOG,NYAP1,DRD1,DSCAM,GOLT1B,EBF1,YAF2,EGFR,RGS17,DENND4A,CDKL3,ATP8A1,FER,SUCO,C1orf61,SLC37A3,C2orf88,ZCCHC17,ZMAT1,GABRA2,GALNT15,GAD1,ARPP21,IQGAP2,DISC1,ATP8A2,GART,GLUL,ZNF638,RAPGEF4,GRIA4,PSIP1,PADI2,AGBL5,ZDHHC15,EID2B,ZNF546,DOCK7,C2CD4C,KCNJ3,ASPRV1,AQP11,EFHB,MEIS2,KCTD6,ZC3H12B,NDP,NF1,SLCO1C1,NFYA,HCN1,NUMA1,P2RX7,CNTN3,PCSK1,PCSK5,PDE3A,PDE4D,PDYN,BEST3,GDAP1L1,SERPINE2,PIK3C2A,PIK3R1,PMP22,POLG,POU3F2,PKIA,VPS13C,PSMD13,PTHLH,PTPRE,SUSD4,RAP1GDS1,ARID4A,RFX4,RLBP1,EXD2,GSTCD,ROBO2,ELP2,RPL15,DGLUCY,SEMA6D,FAM19A1,SGK1,SH3GL3,BTBD3,DHX30,WDR47,FAM214B,CCDC88A,SLC15A2,ELMO2,NAXD,SMARCE1,SNAP25,NPAS3,TAB2,NKAIN2,DIP2A,SEPT3,FGD4,VPS13A,POPDC3,ADGRL3,FBXW11,KLHL4,VWA3A,CUX2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TMEM121,AP4E1,DDHD1,ERCC6L2,TMPO,C5orf64,TPM1,RGMB,SLAIN1,P2RY12,CLDND1,ZIC1,ZNF70,SPIRE1,SMARCAD1,PRDM10,PCDH15,RGS7BP,KAT6A,SMIM8,PHTF2,CASC15,TRAM2-AS1,RNF170,SSPN,SENP7" MicroRNA hsa-miR-758:mirSVR_highEffct hsa-miR-758:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.63E-70 9.14E-67 6.85E-70 6.31E-69 181 753 "TTYH1,ABAT,ACLY,NBAT1,ADD1,ADD3,INTS2,CDC42BPA,MAP4K3,PHF12,DDO,MIER1,NUMB,DDX3Y,ATP2B2,ALDH7A1,PROM1,BMP7,DST,SCAPER,KALRN,PTBP2,CAST,SPAG9,RUNX1T1,TMEM257,MAGI1,UBE2L6,CFL2,CHM,CHN2,COG1,FBXO7,C4orf33,MAP4K4,AKAP6,FAM171B,SIPA1L1,VCAN,KIAA0040,APPL1,CYBB,DNAJC6,ZEB2,LYPD1,NTM,WDR20,NR1D2,SLC25A18,GNE,ARRDC4,DTNA,E2F5,EDNRB,ANKRD46,RASGRP1,KLHL5,FAM13A,GPR61,TMEM74,TLR7,F8,CLVS1,RPS6KC1,FCGR1A,GORAB,SEC24B,FER,SPSB4,SYNCRIP,NBEA,TMEM107,ZNF605,TVP23A,OGA,GAD1,GAD2,MTHFD2,DISC1,STON1,EML4,GRIK2,WIF1,MAEL,RASSF8,HLF,HNMT,ZDHHC15,EID2B,TJAP1,OLFM3,FGFBP3,MEIS1,MEIS2,MID1,NEUROD1,DNHD1,PCSK1,SLC10A4,NALCN,PLP1,HMGCLL1,STRN3,GRAMD1C,DIRAS2,RELN,SYTL2,PTCH1,PLPPR1,MTMR10,ZNF615,RAD17,OXR1,RADX,SLC6A15,GTDC1,RFX3,TMLHE,CARF,ROBO1,ZC3H14,TRAPPC13,LRRTM4,RASA3,PAAF1,ZNF365,SLC14A1,CPEB4,MAST1,SORCS3,MBD5,ZNF415,UNC80,FNBP1,CDK19,CLASP2,CLSTN2,COLGALT2,EPB41L3,LARP4,NEK4,SULF2,STXBP1,KLHL7,ADAMTS17,SYT4,MTCL1,FAM208A,UNC5D,TBCEL,TRIM2,PUM2,GPRIN3,ZFPM2,CRB1,TIAM1,TP53BP2,NPL,TRO,TTC3,GORASP1,BEST1,ZNF28,NDRG4,TCEAL7,ZBTB38,ZNF177,FSTL5,CSDE1,RNF103,TUBA1A,NAV3,LINC00632,WNK2,GOPC,SMIM8,HNRNPA3,PHTF2,FBXO36,FRMD6,SLC4A10" MicroRNA hsa-miR-365:mirSVR_highEffct hsa-miR-365:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.65E-70 9.25E-67 6.92E-70 6.37E-69 156 560 "CCDC85A,ADD3,ERMN,PTCHD1,SPOP,ANK3,EP400,PHF12,UPRT,GPAM,CACHD1,API5,RGS20,ARRB2,PCDHGB4,DYNLL1,RNF182,DPY19L3,ADGRB2,SYNJ1,MTMR2,OSGIN2,KALRN,CBR1,MTMR7,COPB2,CHM,IGFBP7-AS1,CNTN1,BTF3L4,MYRIP,ZFP28,CS,FEZ1,VCAN,PDE4DIP,ERC2,CCDC144A,DOCK4,HDAC9,PITPNC1,ZBTB24,TIAM2,GSDME,DDX46,RHOBTB1,G3BP2,GRIN3A,HS3ST2,NR1D2,DTNA,GOLT1B,EDN1,FSD1L,FAM13A,C3orf18,VPS13B,COQ7,NSRP1,EFEMP1,STRADA,GORAB,FGF1,IP6K2,CELF1,CGREF1,MEGF10,GAA,GABRA2,DISC1,IGSF5,RAB30,TNRC6A,ZNF782,PRUNE2,FUT10,CCDC184,RAPGEF4,GRIK4,MFSD2A,ADAMTS6,IRF8,KLC1,KTN1,LAMP2,ARHGAP12,NCOA7,MARK1,MBNL1,ZNF680,COMMD5,ZNF92,LRIT2,NUCB2,CLDN11,P2RY1,PAK3,PAX6,PCDHGC3,GNG2,BEST3,TRHDE,ING3,GRAMD1C,SIDT1,SNRK,ZNF493,ZDHHC14,REV3L,PCMTD2,ABCA11P,ATXN2,SGK1,SCG5,SEC31A,WDR37,SLC6A1,SLC6A11,USP33,UHRF1BP1L,SSTR2,SYPL1,ANKRD28,TAC3,UNC5D,TBCEL,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,HHIP,TLL2,ZMYND8,CLHC1,SGK3,FAM155A,RICTOR,XPO1,ZNF708,FMN2,SMARCAD1,LRP8,PRDM10,FZD3,HNRNPA3,FAM198A" MicroRNA hsa-miR-19b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-70 1.21E-66 9.02E-70 8.31E-69 176 714 "SDE2,NCKAP5,MTUS1,HECW2,ALAD,PCDH10,GPAM,USP37,MIER1,CAPRIN2,CCAR2,DDX3Y,ATM,STX16,BCL7A,JAZF1,NIPA1,CALM1,PTBP2,MAP7,EVI5L,CFL2,ZFYVE9,QKI,ARMC8,BTF3L4,SLC4A7,ACBD5,ZNF521,CLOCK,PPP6R2,DCAF8,HDAC4,RASSF2,LONRF1,GIT2,DBN1,DCC,SPATA2,YTHDC1,CEP170,KLHL3,G3BP2,MTX3,WDR20,HIPK3,TMTC1,MBNL2,KMT5B,PLXNC1,CERCAM,VPS26C,KATNAL1,WAC,ACSL4,MED12L,CAMSAP1,SEC23B,TMEM107,NPTN,CAB39,ZMYND11,RAPGEF6,AHDC1,MALT1,TNRC6A,PRUNE2,GRK4,RAPGEF4,GRB10,NR3C1,CIT,KIF3A,ELOVL5,C5orf24,ZIC5,CLVS2,ARHGAP12,MBNL1,KITLG,AFF1,ZNF680,SESN3,CCDC80,MYCN,IDNK,NF1,NFIA,CNOT4,TBC1D25,OCRL,PDE4A,PDE4D,FAM218A,CCSER2,PKM,PURG,MBOAT7,TNPO2,FAT3,SH3KBP1,PPARA,PPP2R5E,PRKACB,WBP1L,DEF8,PTPRB,PTPRG,RAB5B,ATG16L1,RBBP8,KLHL11,RNASE1,ZFHX4,CLIP1,SATB1,ATXN1,ATXN7,SOX6,SGK1,FAM102A,CHD9,FNDC3A,SYBU,BTBD3,EPN2,SLC6A8,NAPB,BTBD7,EPC1,KIF13A,PALLD,SON,ZNF423,CDK19,SPART,POGZ,SMOC1,MPRIP,ELOVL4,RGL1,DIP2A,VAMP1,ARC,ANKRD12,CAMTA1,EXOC7,CAMSAP2,ALG1,ATMIN,TCF4,DMXL2,TRIM2,DICER1,ZMAT3,SLC44A1,NACC2,CBX5,DAAM2,TNFRSF1B,WBP2,TRPC3,SLAIN1,TOM1L2,ZNF711,ZNF138,ZNF154,ZFAND5,WNK1,MFF,LRP8,STOX2,WNK3,FXR1,FRMD6,SOCS4" MicroRNA hsa-miR-641:PITA hsa-miR-641:PITA_TOP PITA 2.46E-70 1.38E-66 1.03E-69 9.51E-69 146 490 "ACTN1,FMNL2,USP31,ALCAM,OGT,ANK1,PKP4,GPAM,TMEM263,TMEFF1,DDX3Y,ATP2B1,BACH1,BSN,BTRC,THSD7A,PTBP2,INA,B4GALT6,NMT2,MAP4K4,SLC4A7,NCOR1,OSBPL3,CSNK1G3,CNTNAP2,USP6NL,TOX,SPOCK2,ZNF804A,ZC3H11A,MTX3,DUSP9,DYRK1A,FAM135B,EIF4G2,TENM1,ELAVL2,EMX2,EPHB1,KCNMB2,DNAJC27,FGF13,HPCAL4,FOXO3,STAG2,GABRA4,WASF3,PCDH17,MAP7D2,SERP2,GRM7,IL1RAPL1,MAP4K5,ZHX1,HLF,ELOVL5,ZIC5,KCNA1,OLFM3,KCNA4,KIF5A,KIT,PIK3AP1,MAT2A,ADAM11,CHIC1,BLOC1S2,MXI1,NAP1L1,NEFM,NEFH,NF1,NFIX,NRCAM,HCN1,OMG,PCDH9,PCSK2,PDE3B,PDE4B,CDK14,PIK3C2A,PIK3R1,CCSER2,PLCL1,TRHDE,MAPKAP1,STRN3,LRP12,MED1,MINDY2,PPP2R5E,PPP3CB,KANSL1,PKN2,MAPK10,RELN,PTK2,PTPRG,RIPOR1,RAB5B,ZFHX4,CARF,CLIP1,FAM19A1,FNIP1,SOX6,MAGI3,CHD9,SLC8A2,CXXC4,RCOR3,PALLD,MYT1L,SOX11,HECW1,PEG10,NPAS3,SRPK2,POGZ,ERBIN,MAPK8IP3,RGL1,ANKRD28,TAC1,CAMTA1,SLC35G2,TEK,AP4E1,KAT6B,TPM3,NR2C2,TRPC3,TRPS1,UBE3A,CLDND1,ZIC3,ZNF32,SMARCAD1,SYNC,RGS7BP,KAT6A,HNRNPA3,MSRB3,FRMD6" MicroRNA hsa-miR-186*:mirSVR_highEffct hsa-miR-186*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.50E-70 1.40E-66 1.05E-69 9.65E-69 196 880 "CSMD2,XKR4,PTCHD1,OSBPL6,C1QTNF3,ALCAM,BCAR3,MYH7B,PHF12,PKP4,ANXA7,EPB41L5,CACHD1,APP,ASPH,NCOA1,SLC2A11,N4BP2L1,ADAM23,CACNA1A,CACNA1B,CALB2,TRIM41,VSTM2A,CAST,METTL6,LARGE1,MAGI1,GPR37L1,SOCS6,EPS15L1,RAB28,FAM189A2,CNTN1,AKAP6,CSNK1E,CHD5,NCAN,CTH,GIT2,ZEB2,DDX46,SMG7,SV2A,NTM,RAB39B,DMD,MED12,NR1D2,ABCC9,AASDH,EDN3,FSD1L,PLXNC1,IRAK4,EIF1,TUBD1,KCNMB2,NRN1,STRADA,TESK2,SLC9B2,KIAA1109,FGF13,BAIAP2,UBE2E3,EVL,JKAMP,TMEM107,SMC2,OGA,GABRA2,GABRG2,FAM184B,GAP43,ERAP1,ZNF559,DISC1,NFU1,TCERG1,COPS8,RAB30,GLS,TNRC6A,MAP7D2,RAB40B,GPM6B,CCDC184,KAT7,RNFT2,WIF1,KLF12,CELF5,MSL1,MYLK2,ZIC5,USP54,IL11RA,ITGAM,SLC35G1,KCND1,KCNJ3,KCNK1,STXBP5,NCOA7,MAP2,SRSF12,PPM1L,MN1,MOBP,ZNF680,MSI1,MSR1,CTNNA3,MYO9A,NAP1L1,ZC3H12B,NEK1,NF1,NFYA,PAK3,EPN1,PLP1,SMIM7,CDIP1,EPB41L4B,MED1,PPP2R2B,KANSL1,RANBP3L,PRKACB,EPDR1,LRRC49,SIDT1,CNTLN,BDNF-AS,PTHLH,SPDL1,GTDC1,ELP2,MRAP2,SPIN3,ATP8B4,PAQR6,SEMA6D,NTNG1,NLGN1,PAAF1,LRRC55,ATF7IP,CPEB4,SORCS3,LIMCH1,MBD5,GLT8D1,KIF1B,RBM26,PBLD,CLASP2,SSTR1,ADHFE1,SYNE2,SYT4,CAMTA1,ADGRL3,AGTPBP1,VWC2,SYNE1,DOCK9,NSD1,PUM2,RNF216P1,HEY2,KAT6B,TPM4,PRMT8,RUNDC3B,AMACR,STXBP4,TRPC1,SGK3,PLEKHH2,BCL2L13,VAV1,MEAF6,NSD2,CLDND1,RICTOR,XRCC4,RNF103,PCDH15,MPPE1,DNAH10,DOCK8,RNF170,DPF3" MicroRNA hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA_TOP PITA 2.88E-70 1.62E-66 1.21E-69 1.11E-68 130 384 "ABHD6,SORCS1,NLGN4X,MTUS1,OSBPL8,ALCAM,FAM135A,C6orf89,ANXA7,ALS2,APP,SHTN1,DDX3Y,NOL4,MTMR2,JAZF1,GPC2,PTBP2,CERS5,C1orf52,LRBA,MAGI1,NRXN3,CLCN4,MAP4K4,CNR1,APPL1,PUM1,ST18,DOCK4,DAPK1,BRINP1,ELMSAN1,DNAJC6,FBXL5,KLHL3,G3BP2,CDON,CASP8AP2,ABI1,RCAN1,DNAJB6,GOLT1B,HIPK3,FRY,EFNA3,YAF2,KMT5B,ABI2,EGR3,EIF4G2,ELAVL2,EIF1,SEZ6,ERBB4,SUCO,MEX3B,FUT9,STAG2,NEK6,ARFIP1,PPARGC1A,MSL3,PCDH11X,GRM1,GRM7,MAP4K5,MIER3,HNRNPK,ZIC5,KCNQ3,MAT2A,CHIC1,MITF,MKLN1,SESN3,MXI1,NFIX,PCDH8,PRTG,PDE4B,PDE4D,CDK14,PIK3C2A,PLCL1,LRP12,MED1,PKN2,RAP1GDS1,ENOX1,RBBP6,PBRM1,ZFHX4,SEMA6D,ATXN1,FNIP1,SGK1,CPEB3,CHD9,SLITRK3,CPEB4,COA1,PALLD,MYT1L,LMO3,LRRC4,ERBIN,ATP11A,CAMTA1,ADGRL3,FBXW11,TCF4,ZFPM2,AP4E1,SLC44A1,ZFP91,TRPS1,TMEFF2,SLAIN1,BEST1,VSNL1,ZIC2,MICU3,EMSY,SNX27,SLC17A6,FAM13C,ACTR3B,SENP7,JPH3" MicroRNA hsa-miR-1262:mirSVR_highEffct hsa-miR-1262:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.98E-70 1.67E-66 1.25E-69 1.15E-68 187 805 "RALGAPA1,ADD3,KIDINS220,BEND6,NLGN4X,AGT,KCTD16,RTL9,OSBPL1A,TXNDC16,ARHGAP20,CNIH2,PKP4,SEMA4G,ARRB1,ARRB2,ZSCAN18,DDX3Y,BARD1,SEC11C,ZNF599,SYNJ2,ARHGEF7,CACNB2,LURAP1,CAMK2D,CAST,CD38,C1orf52,LRRFIP1,TAOK2,LSMEM2,NRXN3,QKI,CNGA3,CPS1,CLIP3,CSF1R,ARHGEF10,AK5,FAM107B,DLG2,DYNC1I1,DNM1L,EBF1,EDNRA,EDNRB,SGK2,KLHL5,FSD1L,MBNL2,TMEM132E,PLEKHA1,EPHB1,MRPL37,TLR7,EXTL2,F8,EFEMP1,KAT8,POLR1B,FGF11,FGF13,FGFR1,MEX3B,CAP2,SLC37A3,ZCCHC17,STAMBP,NRG3,SALL3,DISC1,LRRC37A6P,GCNT2,WASHC2A,MALT1,INSM2,GNAS,PCLO,GRM7,LINC01551,FAM222A,UBE2QL1,NXPH2,AGBL5,TCEAL6,DOCK7,ZNF385B,LRRTM3,SYTL4,NCOA7,MAN2A2,MAT2A,MATN2,MN1,MRPL42,SESN3,CCDC80,MSR1,RTL5,TCEAL5,NCAM1,NEK1,NPY,NOVA1,SLC11A2,DDR2,OPA1,OPHN1,ETFRF1,PCSK1,PDE4D,ZNF655,JAKMIP1,PLXNB3,PURG,PPP2R5E,CEP41,PKIA,MTMR10,PTPRB,ZNF615,RFX4,RIC8B,GSTCD,YY1AP1,RPE,SPIN3,WLS,ZNF568,NLGN4Y,SH3GL3,FERMT1,KIF16B,NTNG1,CHD9,BCAN,SEC31A,SLC8A1,SLC8A3,ATF7IP,TET1,SMARCE1,RCOR3,SOX2,DOK5,ENKUR,HECW1,KDM4C,KIF1B,IQSEC2,C11orf87,PBLD,COLGALT2,EPB41L3,ZSCAN29,SEPT8,FGD4,VAMP1,COBL,ADGRL3,KLHL4,PCDHB7,C18orf54,ITGB3BP,LEFTY2,ARL10,TJP1,LRRC8A,FNDC5,USP1,BEST1,PORCN,SF1,ZFP37,ZIC3,ZNF142,CA10,EMSY,CADM2,LRP8,FAM47E,EPM2A,RGS7BP,FAM13C,NETO2,JPH3" MicroRNA "ACCAAAG,MIR-9:MSigDB" "ACCAAAG,MIR-9:MSigDB" MSigDB 4.21E-70 2.36E-66 1.76E-69 1.62E-68 143 471 "ASIC1,ARID1A,SLC12A5,RNF150,ESYT2,HECW2,ALCAM,ANK2,PARG,GPAM,SHTN1,ARHGDIA,NCOA1,CCAR2,SYNJ1,MYRF,CALB2,KALRN,PTBP2,MAP7,USP6,ARHGEF2,EVI5L,FAM19A5,QKI,CNTFR,COL9A1,TBPL1,CLOCK,C2CD2,CREB5,NCOR2,OSBPL3,SOCS5,RIMS4,RIMS2,ARHGAP24,RIMS3,DGKB,ARMCX2,KLHL3,RHOBTB1,SACS,SRGAP3,FAM107B,CPEB2,DYRK1A,CNNM1,FRY,PHF20L1,EGR3,SORBS3,EIF5,TENM1,SEZ6,KCNMB2,CHST15,TESK2,FGF12,FOXG1,CAMKK2,GAD1,BRPF3,ARPP21,MTHFD2,C1QL1,CBX1,ADAMTS13,ADAMTS6,KLF12,ACOT7,AGFG1,KCNMA1,MBNL1,SYT9,ADAM11,KITLG,MMP16,DBNL,MDGA1,NAP1L1,NEK1,NPTX1,OPCML,CNTN3,PCSK2,GPR85,ZNF655,CCSER2,XRN1,PMP22,PRRX1,PACSIN1,POU3F2,PPARA,CNNM2,SNRK,MDGA2,TMEM260,RALGDS,RET,PRRT2,RIC8B,HUNK,SEMA6D,SCN2B,LRRTM4,TRA2B,KIF21A,NTNG1,AMBRA1,ZNF365,SLC20A2,CPEB4,CMTR2,TMCC1,SON,WDTC1,FNBP1,SPART,NFASC,TAB2,ERBIN,ELOVL4,STX1A,VAMP1,ATP11A,ANKRD12,TRIM2,DOCK9,SIRT1,AP4E1,RBFOX2,RASD2,NSD2,CELF4,SLC30A3,PRDM10,ITM2C,GOPC,FAM13C,PHTF2,FRMD6" MicroRNA hsa-miR-342-3p:mirSVR_highEffct hsa-miR-342-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.29E-70 2.41E-66 1.79E-69 1.65E-68 175 709 "ADORA2A,AP2A2,KCTD16,OSBPL8,TAOK1,SMIM17,ALCAM,DPP10,MYH7B,LGR5,AQP4,TMEFF1,NUMB,ASTN1,CCAR2,DDX3Y,NOL4,NRP2,OSGIN2,CA12,SYT6,CAST,PRC1,METTL6,CIART,CHM,FBXO7,TJP2,ARMC8,FAM149A,SLC4A8,MYRIP,ZFP28,GDA,CTNND1,CTNND2,HDAC9,MATR3,SPATA2,ZEB2,PLEKHM1,KIAA0753,PLPPR4,SPOCK3,NTM,AK5,CHRDL1,DSCAM,EGFR,DENND4A,ZNF585B,ZIC4,CEP78,FOXG1,SEC23B,NOP56,TRMO,NBEA,TPK1,NSG1,SARAF,DKK3,ILDR2,COPS8,GLDC,GLS,KDM2B,ADGRA3,GPD2,GPM6A,LPAR4,BTN2A1,SOX21,ADAMTS6,WIF1,ATXN2L,CPT1C,HTR2A,MYLK2,ITGAM,METTL21A,KIF2A,NCOA7,PIK3AP1,MAN2A2,MBNL1,TM6SF1,MEIS1,KCTD6,POC1B,MRPL42,PTOV1,MT3,MXI1,P2RY13,NKX2-2,DNHD1,NTRK2,PCSK5,PDE1A,PDGFRA,CAMKV,NOMO2,ANLN,PPM1B,SNRK,MDGA2,TMEM260,OCIAD1,PTPRN2,RAD52,ZNF793,SLC6A15,ZYG11B,PRIMA1,TTLL7,SEC61A2,SLC25A36,RORB,NEK11,RPL15,SPIN3,WLS,ZNF568,FAM192A,RMI1,SOX6,SGK1,NUBPL,KDM4D,NAPB,SPHKAP,DMRTC1,SNAP25,SNCA,RBM34,EMC1,NPAS3,CLSTN2,SAMSN1,TTBK2,PRRC2C,VAMP1,ARHGEF9,ADAMTS17,DNAJC9,SYT4,MMS19,FAM208A,TBX15,ZEB1,TCF12,DOCK9,NSD1,FRYL,SIRT1,TIAM1,PRRT1,SYNPO2,TRIO,AMACR,ZKSCAN5,RICTOR,PCDH20,ZNF711,FMN2,CELF4,LAMP5,SMARCAD1,UPF3A,ZNF225,LRP8,PRDM10,TMEM178A,GOPC" MicroRNA hsa-miR-1827:mirSVR_highEffct hsa-miR-1827:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.09E-70 2.86E-66 2.13E-69 1.96E-68 212 1024 "KCNH8,ASIC1,XKR4,ADCY2,ADCY6,GALNT13,SLC12A5,PLEKHH1,KIDINS220,ZNF608,KIAA1324,LRRC7,FAM135A,ANK3,EP400,PPFIA4,SUGT1P4-STRA6LP-CCDC180,UPRT,ALS2,TNRC6C,STK33,CAPRIN2,DACT3,CHRD,ATP1B3,ZNF583,B3GALT2,ADAM15,CFLAR,KSR1,JAZF1,GPC2,BSN,CA8,CACNB2,CALB1,THSD7A,MAP7,CBS,CLDN10,MAGI1,DLGAP1,CCPG1,EPS15L1,FAM19A5,MAP4K4,CNN3,ARMC8,LETMD1,GAL3ST1,ANKRD44,CS,CSF3R,CTNND2,CX3CR1,CYBB,GPRASP1,DCAF8,PHF19,CENPL,EARS2,ELMSAN1,HP1BP3,C2CD2L,SV2A,TMCC2,USP3,ACOT8,DNM1L,EBF1,KLHL5,YAF2,EFNB3,EBI3,PLEKHA1,C8orf37,DCTN4,SLC43A2,PIPOX,SIRPB1,RACK1,FCGRT,STRADA,KAT8,SLC9B2,SPSB4,FGF14,SUCO,SYNCRIP,PSD2,ATP6V1H,STAU2,GABRB1,FAM120B,IQGAP2,INPP5K,TUBA8,GFAP,GLI2,GLS,GPD2,TDRKH,CCDC184,PCLO,C1QL4,LINC00839,FAM19A2,RNF165,SMAP1,RAB41,ZNF546,ZIC5,RBPJ,IGSF1,ZNF678,INSM1,NME9,ITGA7,ITGAV,KCND2,KHK,KTN1,HECTD2,SMAD1,MAN2A2,MATN2,SYT9,CD200,MRPL42,TMEM249,MYO9A,NDUFA5,SFR1,NELL1,NELL2,NINJ2,NNAT,VWA2,CNOT4,SLC11A2,NTRK3,NUMA1,TBC1D25,OCRL,OPHN1,CDK18,PDGFRA,GDAP1L1,SERPINE2,PLCL1,PLIN1,PURG,SCHIP1,POU3F2,PPP2R5C,DCHS2,SNRK,PLPPR1,PEX5,ZSCAN2,ZNF615,TRIM68,DPF2,CARF,MRAP2,SCP2,ELMOD1,CASC3,TRA2B,COPZ1,ZFP30,FUZ,SHC4,ST3GAL3,CTXN2,IFT122,SNRPN,WDTC1,TNIK,CAND2,ZC3H13,ZSCAN29,ADHFE1,FAM168A,KLHL7,SYT1,MTCL1,MCF2L,FAM208A,ANO4,WDR7,GPRIN3,FRYL,AHCYL2,TIE1,HEY1,NR2E1,ZMYND8,KCNE5,TMPRSS5,SSBP2,CCDC136,SF1,ZNF154,STOX2,MDH1B,SLC17A7,EPM2A,CAMK1G,RNF170,NETO2,JPH3" MicroRNA hsa-miR-4298:mirSVR_highEffct hsa-miR-4298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.01E-70 3.38E-66 2.51E-69 2.31E-68 182 767 "RALGAPA1,KCNH8,KLHL32,CCDC85A,GALNT13,ADD3,BRAP,PWWP2A,UPRT,VAT1L,AQP6,CCAR2,ATM,ATP2B2,ZNF583,ADGRB2,NRP2,DST,ARHGEF7,CALB1,SYNGR3,CD38,ENTPD6,LRRFIP1,CDO1,PPT2,SUMF2,COL9A2,ABI3BP,CHD1L,HINFP,ANKRD44,GDA,SDC3,RUBCN,GPRASP1,ARHGAP32,RIPOR2,ZBTB24,ALKBH8,RAB39B,DYNC1I1,SLC12A6,ABI1,GNE,DTNA,ABCC9,E2F6,EDN1,YAF2,APH1A,EPHB1,NCALD,RTN3,F5,F8,ARMCX1,PTK2B,FCGR3A,ACTL6B,FGFR1,CAMSAP1,SCARA3,SLC37A3,SPECC1,NEURL4,GABRA5,AHCYL1,ARPP21,IQGAP2,DISC1,RAB30,TNRC6A,GLUL,ZNF638,LUZP2,PRUNE2,GRIA2,NR3C1,GRM8,FAM19A2,MAEL,MIER3,NKD1,KIAA1755,DIPK1A,LRRTM3,LRRTM1,KCNQ3,STMN1,LIG4,MBD1,TM6SF1,LRP1B,KITLG,MOBP,COL28A1,NEXMIF,NELL1,NME4,VWA2,CNOT4,PCDH9,BEST3,DUSP26,SNX10,PLCL1,SLC36A4,MED1,SAMD9,VPS13C,OCIAD1,PYGM,OXR1,HKR1,GSTCD,GLDN,ABCA11P,NCBP3,LRRTM4,LINC00461,SEC14L1,SH3GL3,NTNG1,HKDC1,MAGI3,FBXO11,SLITRK3,SYBU,SEC31A,FAM81A,BTBD3,ATF7IP,ZNF667,INAVA,RIMS1,MAPKBP1,ANKFN1,KDM3A,KDM4C,KIF1B,CDK19,TAB2,NKAIN2,MPRIP,SULF2,GANAB,SEPT3,VAMP1,SYN1,SYN2,SYT1,FAM208A,TCEA1,ACSL6,SYNE1,SLC19A3,OBSL1,CYB561A3,AP4E1,GZF1,RASD2,TPM3,METTL3,TRPS1,RUSC1,TSC1,HSPBP1,TMEFF2,VSNL1,PCDH20,ZNF45,TMEM237,MAP3K12,XKR7,SIGLEC10,SNX27,FAM47E,C12orf4,DOCK8,ST7,PHTF2" MicroRNA hsa-miR-363:PITA hsa-miR-363:PITA_TOP PITA 6.04E-70 3.40E-66 2.52E-69 2.32E-68 145 486 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-211-5p:TargetScan hsa-miR-211-5p TargetScan 6.50E-70 3.65E-66 2.71E-69 2.50E-68 156 565 "DPF1,NDRG3,ADARB2,ADCY6,RNF157,ADD3,GRAMD1B,ESYT2,AP2A2,KLHL13,BIN1,OGT,ARHGAP5,ARRB1,CDK13,MARCH3,DYNLL1,ATP2B1,BCL2L2,BCL7A,CAMK2D,RUNX1T1,MTMR7,CDH2,CCPG1,CHN2,PLAA,NIPBL,FHL5,PCYT1B,SEC31B,CREB5,HAPLN1,CHD5,CNTNAP2,CTH,RIMS2,NOS1AP,HDAC9,GAPVD1,DCAF8,PHF19,DGKG,DNAL1,DCC,ELMSAN1,GUCD1,RHOBTB1,RABGAP1L,FAM107B,DNM2,DMTF1,DYRK1A,EFNB3,CELSR3,ELAVL2,ELAVL3,ELAVL4,EIF1,EPHA5,EPS8,RPS6KC1,CACNG2,ACSL4,SCML2,AGAP2,ANKFY1,NBEA,KHDRBS3,NSG1,NRG3,GABRB3,BRPF3,NEK6,GCNT2,PPARGC1A,GPT2,GPM6A,NR3C1,IL1RAPL1,HAS2,FRMD5,NCKAP1L,KLF12,MIER3,HMGB1,HMGCR,HMX1,IL6R,SCRT2,INSM1,JAK2,KCNA1,KCNC2,KCND3,IPO5,NCOA7,LSAMP,MBD1,MBNL1,MEIS1,MEIS2,MGAT3,SAMD5,MXI1,NFIA,NOVA1,OPCML,P2RX7,PAK3,PDE3A,PDE4A,FTO,PRRX1,FAT3,POLR2F,POU3F2,PTPRD,PTPRG,CCDC40,GTDC1,KLHL11,SEC61A2,ROBO1,RORB,FBXW7,RIMKLA,LGR4,CSRNP3,ATXN1,FNIP1,HSPA4L,PPP1R9A,PPM1E,ARX,MYO18A,LRRC55,BTBD7,CPEB4,MBD5,MYT1L,PEG10,ARHGAP26,NPAS3,RAP1GAP2,ANKRD12,DNMBP,SATB2,ASXL3,RICTOR,REEP1,LRP8,ADAMTS9,RNF170,GAN,JPH3" MicroRNA hsa-miR-204-5p:TargetScan hsa-miR-204-5p TargetScan 6.50E-70 3.65E-66 2.71E-69 2.50E-68 156 565 "DPF1,NDRG3,ADARB2,ADCY6,RNF157,ADD3,GRAMD1B,ESYT2,AP2A2,KLHL13,BIN1,OGT,ARHGAP5,ARRB1,CDK13,MARCH3,DYNLL1,ATP2B1,BCL2L2,BCL7A,CAMK2D,RUNX1T1,MTMR7,CDH2,CCPG1,CHN2,PLAA,NIPBL,FHL5,PCYT1B,SEC31B,CREB5,HAPLN1,CHD5,CNTNAP2,CTH,RIMS2,NOS1AP,HDAC9,GAPVD1,DCAF8,PHF19,DGKG,DNAL1,DCC,ELMSAN1,GUCD1,RHOBTB1,RABGAP1L,FAM107B,DNM2,DMTF1,DYRK1A,EFNB3,CELSR3,ELAVL2,ELAVL3,ELAVL4,EIF1,EPHA5,EPS8,RPS6KC1,CACNG2,ACSL4,SCML2,AGAP2,ANKFY1,NBEA,KHDRBS3,NSG1,NRG3,GABRB3,BRPF3,NEK6,GCNT2,PPARGC1A,GPT2,GPM6A,NR3C1,IL1RAPL1,HAS2,FRMD5,NCKAP1L,KLF12,MIER3,HMGB1,HMGCR,HMX1,IL6R,SCRT2,INSM1,JAK2,KCNA1,KCNC2,KCND3,IPO5,NCOA7,LSAMP,MBD1,MBNL1,MEIS1,MEIS2,MGAT3,SAMD5,MXI1,NFIA,NOVA1,OPCML,P2RX7,PAK3,PDE3A,PDE4A,FTO,PRRX1,FAT3,POLR2F,POU3F2,PTPRD,PTPRG,CCDC40,GTDC1,KLHL11,SEC61A2,ROBO1,RORB,FBXW7,RIMKLA,LGR4,CSRNP3,ATXN1,FNIP1,HSPA4L,PPP1R9A,PPM1E,ARX,MYO18A,LRRC55,BTBD7,CPEB4,MBD5,MYT1L,PEG10,ARHGAP26,NPAS3,RAP1GAP2,ANKRD12,DNMBP,SATB2,ASXL3,RICTOR,REEP1,LRP8,ADAMTS9,RNF170,GAN,JPH3" MicroRNA hsa-miR-802:PITA hsa-miR-802:PITA_TOP PITA 6.66E-70 3.74E-66 2.77E-69 2.56E-68 140 452 "FMNL2,AXIN2,SLC12A5,PCDH19,OSBPL8,AMPD3,OGT,APC,ZBTB10,STX16,MPDZ,CAMK2A,CANX,SPAG9,LGI1,CFL2,SRSF11,CHN1,LHX2,KMT2C,KIAA1549L,CLCN4,NMT2,HECTD1,NIPBL,BTF3L4,SLC4A7,BAG4,ZNF521,IGDCC3,SLC35F1,CRMP1,SOCS5,EDRF1,DGKB,DBI,MYEF2,SNAP91,G3BP2,CPEB2,DMTF1,GNE,EDN1,CELSR3,MBNL2,GOLGA7,ELAVL2,ELAVL3,PAN3,CAMSAP1,MEX3B,STAU2,MSANTD4,OGA,GABRB3,CAB39,HBS1L,IQGAP2,GLS,GPD2,LPAR4,RFFL,GRM1,CIT,PSIP1,KLF12,MIER3,AGFG1,SMAP1,NKD1,TJAP1,LRRTM3,KCNA4,STMN1,LIFR,MIA2,KITLG,MITF,MSI1,NEXMIF,NEUROD1,NRCAM,PCDH9,CCSER2,PCDH18,STRN3,TNPO2,MINDY2,PPP3CA,PKIA,PTCH1,PTPRD,PTPRG,FAM120C,PTPRZ1,CEP97,TMEM255A,REV3L,FIGN,UBR7,NUDT11,ZFHX4,RTN1,SATB1,CPEB3,NLGN1,WDR37,BTBD3,SLC8A1,TMCC1,SOX5,SOX11,CDK19,SRPK2,CLASP2,STAU1,NECAB1,UNC5D,ADGRL3,FBXW11,TCF4,ZFPM2,HHIP,KAT6B,RBFOX2,UBE3A,SLAIN1,FLRT2,SF1,ZIC3,ZNF711,MICU3,TRIM9,ADAMTS9,SCG2,NAV3,GOPC,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-377-3p:TargetScan hsa-miR-377-3p TargetScan 7.83E-70 4.40E-66 3.26E-69 3.00E-68 143 473 "ARID1A,RNF150,KCTD16,AK2,ABCD2,PCDH10,C6orf89,MADD,ARRB1,MARCH3,NCOA1,NRP2,FUBP1,MTMR3,JAZF1,CACNA1I,OSGIN2,BSN,CA12,CACNA2D1,RUNX1T1,AIFM1,DLGAP2,CACNA2D2,RAB3C,B4GALT6,ARMC8,AKAP6,AKAP5,HS3ST5,ENTPD4,PYGO1,DNAJC6,HP1BP3,C2CD2L,RABGAP1L,RAB39B,CDON,E2F6,EDNRB,SEMA3D,GPR61,PLXNC1,AASS,C8orf37,EPB41,DMTN,FGFR1,FLNC,NBEA,CELF1,GAD2,ATP8A2,FAXC,NFU1,PPARGC1A,COPS8,GLYR1,GPR75,GRIA1,NR3C1,RNF165,RASSF8,NXPH2,FRMD3,IGFBPL1,HNRNPK,NEGR1,MSL1,IGF1,C5orf24,KCNA6,KCNB1,KCNK1,KCNK3,KCNN3,KIF2A,KIFC3,IPO5,CAMK2N2,LSAMP,ADAM11,MMP16,MXI1,NKX2-2,NOVA2,OCRL,PAK3,PDE4D,PDGFRA,GPR173,GPR85,GDAP1L1,CAMKV,LRP12,PKIA,PTPRB,PLEKHB2,RDX,FIGN,RFX3,ARHGEF10L,KLHDC8A,HUNK,FAM192A,CSRNP3,FAM19A1,PPP1R9A,NAPB,BTBD7,CPEB4,ARHGAP26,NPAS3,LARP4,MPRIP,DIP2A,PLCB1,ANKRD28,KAZN,CAMTA1,FAM208A,RPGRIP1L,NSD1,PUM2,GPRIN3,BHLHB9,PRRT1,DOK6,HEPACAM,CADM1,EIF4ENIF1,PLEKHH2,REEP1,DPYSL5,LRP8,RGMA,CIAPIN1,MVB12B,KAT6A,JMJD1C,MSRB3,NETO1,GAN" MicroRNA hsa-miR-92a:PITA hsa-miR-92a:PITA_TOP PITA 8.19E-70 4.60E-66 3.40E-69 3.13E-68 145 487 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-25:PITA hsa-miR-25:PITA_TOP PITA 8.19E-70 4.60E-66 3.40E-69 3.13E-68 145 487 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-92b:PITA hsa-miR-92b:PITA_TOP PITA 8.19E-70 4.60E-66 3.40E-69 3.13E-68 145 487 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-367:PITA hsa-miR-367:PITA_TOP PITA 8.19E-70 4.60E-66 3.40E-69 3.13E-68 145 487 "SDE2,CSMD3,DSCAML1,SLC12A5,GRAMD1B,FAM135A,PITPNM2,DPP10,ANK3,USP28,DDX3Y,SLC4A4,ATP2A2,MTMR9,B3GALT2,HCN2,CDK5R1,SYNJ1,CACNA1I,BSN,CAMK2A,CDH10,DLGAP2,SOCS6,PCYT1B,SLC32A1,AATK,SOCS5,SLITRK5,ERC2,APPL1,DOCK4,SPOCK2,GIT2,SIRPA,DBT,PITPNC1,ZNF804A,ZEB2,G3BP2,DLG2,CPEB2,ARRDC4,HIPK3,FRY,EFNB3,KMT5B,PLEKHA1,RGS17,PCOLCE2,KIAA1109,FOXG1,TACC2,NPTN,DKK3,IQGAP2,GAP43,GHR,PCDH11X,PRRC2B,GPD2,GPM6A,GRIA1,GRM1,MIER3,ITGAV,KCNA1,INSYN2,LMO2,PIK3AP1,MARK1,LRP1B,AFF1,SESN3,MYO5A,NEFM,NEFH,NF1,NFIA,NFIX,NOVA1,NPTX1,KSR2,CLDN11,GPR137C,KCNK10,CCSER2,SNX10,XRN1,TRHDE,STRN3,CEP41,PTPRD,PTPRO,TMEM255A,PLEKHB2,BSDC1,REV3L,FIGN,RGS3,SLC25A36,ZFHX4,SETD5,ROBO1,ROBO2,RPL15,FBXW7,AP1AR,SEMA6D,ATXN1,SCN3A,FAM19A1,FNIP1,CPEB3,MYO18A,CPEB4,PALLD,FAM126B,PDZD2,MYT1L,SOX11,MYCBP2,TEX2,ITPRID2,ELOVL4,RGL1,SYN2,SYT1,ANKRD28,CAMTA1,DOCK9,HHIP,CSMD1,TSC1,SGK3,ZNF711,FMN2,EVI5,SLC17A6,RGS7BP,PHTF2,ADAMTSL3,MSRB3,FXR1,SLC4A10" MicroRNA hsa-miR-517b:mirSVR_lowEffct hsa-miR-517b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.51E-70 4.78E-66 3.53E-69 3.25E-68 164 626 "KCNH8,KLRC4,ADD1,NME5,OSBPL6,ADGRF5,SPARCL1,ALCAM,TRMT9B,ZFAT,DPP10,CCDC146,MAP4K3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APBB1,APBB2,PHYHD1,SHTN1,CAPRIN2,ZNF582,MTMR9,SNAI3-AS1,MPDZ,CACNB2,CABP7,ISPD,ARHGEF2,CDC42,NOG,COG1,HECTD1,IGLON5,ZNF521,ATRNL1,VCAN,VAC14-AS1,SLITRK5,USP6NL,CCDC144A,ARHGAP24,DAPK1,DBN1,ZEB2,MFAP3L,AK5,GRIN3A,USP3,CPEB2,DNAJB6,EDN1,ATL1,RASGRP1,PLEKHA1,STARD3NL,C8orf37,PAN3,EPHA5,TAOK3,FECH,POLR1B,FOXF2,SLC37A3,TACC2,ERGIC3,FYB1,GAB1,TOX3,HTATSF1,GPR19,LPAR4,PCLO,GRIA2,GRIN1,GRM8,BTN2A1,HAS2,TNFAIP8L3,C9orf129,HSD17B1,IGFBP1,NKD1,ITGAM,KCNN2,KIF5C,LIG4,MARK3,MEIS2,TAGLN3,ZC3H12B,NDP,NELL2,NFIA,GPR88,OMG,PDE3A,PDE4D,ENPP2,SEMA5B,FAM216A,STRN3,ING3,POU3F2,PPP3CB,KANSL1,CEP41,PKIA,PKN2,EPDR1,ZIK1,PTPN13,FAM184A,ARID4A,RFX3,RFX4,RGS12,TTLL7,RIC8B,LGI2,CARF,ROBO1,ROBO2,UEVLD,LRRK2,HOGA1,TRA2B,CPEB3,WDR47,SEPHS1,SORCS3,RCOR3,ANKRD36,SNCA,MBD5,WDTC1,SOX2,FNBP1,ZBTB43,TAB2,TROVE2,EPB41L3,AJAP1,TAC1,AGTPBP1,MGRN1,RPGRIP1L,WDR7,ZFPM2,CRB1,AP4E1,TJP1,TPM1,PRMT8,FAM155A,FLRT1,USP1,CELF4,EML6,CSDE1,TMEM163,WNK2,SLC17A6,CBLN2,FAM198A" MicroRNA hsa-miR-626:mirSVR_highEffct hsa-miR-626:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.63E-70 4.85E-66 3.57E-69 3.29E-68 176 720 "VWA5B2,KCNH8,NCKAP5,NDRG3,FAHD2CP,WDR35,DPP10,MAGEE2,PHYHD1,SHTN1,STK33,ASPH,DDX3Y,ATM,DPY19L3,KSR1,CALB1,PTBP2,MAGI1,SYNPR,NDST3,NRXN3,COG1,ARHGEF6,CNR1,FAM149A,AKAP6,COL4A5,COL9A1,CNRIP1,C2CD2,ENTPD4,RBM39,ANKRD44,GDA,TRIM69,ABCG1,CSNK1G3,VCAN,UBXN2A,HDAC9,KIAA0586,DGKB,GIT2,HEPH,MYEF2,FBXL5,CEP170,MAGI2,ZC3H11A,AK5,SLC25A18,DSCAM,DTNA,ABCC9,EBI3,PAN3,EPHB1,GPHN,ANKRD13B,DENND4A,CDKL3,EYA1,FAM198B,GTF2IRD2,FGF14,POLK,COQ5,WDR83,SPECC1,CAMKK2,CELF1,ST6GALNAC3,ZNF512,GABRA5,GABRG2,GAD2,NCKAP1,C15orf41,ARFIP1,GGTA1P,PPARGC1A,GK,GPD2,LILRA2,MAP4K5,VSIG4,LRRC75A,IGF1,KNDC1,USP54,DIPK1A,KCNB1,KCNJ9,KCNJ16,KIF2A,STXBP5,NCOA7,SMAD9,MBNL1,MEIS2,MITF,XRRA1,MMP16,CTNNA3,GLIPR1L2,SNTG1,DPY19L2P2,PCDH9,PDE4D,GNG2,PPM1B,KANSL1,MAPK8,PRPSAP2,SAMD9,CNTLN,TMEM260,PTPRG,RAB5B,RBBP6,RIT2,SLC25A36,CARF,ZC3H14,ATP8B4,GLDN,ATAT1,SUPT20H,SYBU,FAM81A,FAM214B,SLC14A1,SLC22A4,ZFP1,IFT122,RIMS1,TNIK,ZCCHC24,MYCBP2,IDI2-AS1,LRRC4,ERBIN,SEPT8,FNDC9,PLCB1,SYT1,FBXW11,ZFP90,AKNA,USP32P1,GPRIN3,TMPO,RGMB,PPIL6,RFTN2,TMEFF2,UBE2H,SLAIN1,BCL2L13,BEST1,WIPF1,XRCC4,ZBTB14,PLPP4,ZBTB38,REEP1,EML6,PCDH15,FIP1L1,PARP11,PDSS2,PHTF2,FAM219B,RNF170,NETO1" MicroRNA hsa-miR-495-3p:TargetScan hsa-miR-495-3p TargetScan 9.97E-70 5.60E-66 4.13E-69 3.80E-68 163 619 "DPF1,CPNE2,RNF150,PTCHD1,GPR158,KCTD16,KIAA1324,OSBPL8,C1QTNF3,ARHGAP20,PCDH10,DPP10,APC,PDE8B,NCOA1,DDX3Y,ATP2B2,BMP7,FUBP1,LDLRAD4,CACNA2D1,CAMK2G,CAST,CBFA2T2,CDH2,DLGAP2,GPR37L1,LHX2,NRXN3,KIAA1549L,NRXN2,NMT2,CNR1,BTF3L4,SEC31B,CLOCK,IPCEF1,RIMS4,PLXNA4,PITPNM3,PLCXD3,CTNND2,CCDC144A,PYGO1,FRMPD4,PHF19,BRINP1,DBI,HP1BP3,DMD,DRP2,DYRK1A,KLHL5,RBM12,CELSR3,MBNL2,AASS,ELAVL3,RGS17,COQ7,ERBB4,CEP85L,ATP8A1,AMOTL2,FOXG1,PDLIM5,NSG2,CELF1,B3GAT1,GAB1,GABRA1,GAD2,RAPGEF6,IP6K3,ATP8A2,GBX2,KDM2B,GPD1,GPR22,RAPGEF1,DIDO1,RFFL,HMGB1,HMGCR,NEGR1,AGFG1,HSP90AA1,IGF1,LRRTM3,C2CD4C,KCNN3,NAT8L,LDLRAD3,MSI1,MYO9A,MYT1,NAP1L1,PAK3,PCDH8,PDE3A,FAM216A,PLCL1,FTO,POU3F2,PPP2R2C,CRLS1,KANSL1,MAPK10,PTPRG,RFX4,KLHL11,RPRD1A,RAVER2,ROBO1,RORB,MCMBP,SATB1,SCN8A,HSPA4L,PPP1R9A,NTNG1,FBXO11,R3HDM2,CCDC92,CCDC88A,INTS9,FAM126B,FNBP1,NPAS3,RAP1GAP2,CLSTN2,MPRIP,AJAP1,GSE1,RHBDL3,ARC,DDHD2,MCF2L,CNTN2,ACSL6,RPGRIP1L,CLASP1,ARHGEF12,DICER1,AP4E1,GZF1,NACC2,CBX5,ASXL3,RBFOX2,RASD2,LRTM2,CADM1,AMOT,PORCN,RICTOR,MFF,MVB12B,FXR1,NETO2,NETO1,GAN,CPNE4" MicroRNA hsa-miR-657:mirSVR_highEffct hsa-miR-657:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-69 6.11E-66 4.50E-69 4.15E-68 175 713 "SDE2,ABAT,KCNH8,ASIC2,CLK4,AS3MT,NCKAP5,BRAP,SLC44A5,ZNF608,INTS2,KIAA1324,OSBPL8,TXNDC16,AMT,CNTNAP1,USP37,CDC14B,SEMA4G,ATM,EIF4G3,B3GALT2,NRP2,PROM1,CAMK2D,CAST,USP6,DGKI,CCPG1,NOG,QKI,SULT4A1,ARHGEF6,CNTN1,AKAP6,SLC4A7,TBPL1,DZIP3,KIAA0040,ERC2,CCDC144A,ARHGAP32,FGFR1OP2,RIPOR2,DCAF8,TOX,MYEF2,RHOBTB1,SPOCK3,DLG2,PDCD6IP,KLHL5,PHF20L1,EGFR,EML1,CALCRL,LRRC17,EFS,RTN3,F8,FAM198B,TAOK3,ZNF589,GORAB,GTF2IRD2,FHL1,NBEA,SMC2,ATP2C1,ZNF605,ST6GALNAC3,DKK3,GABRA1,GABRG2,ZNF234,LRRC37A6P,ARFIP1,AHDC1,PCDH11X,DCLK2,GNG4,GRIA4,KAT7,LINC01551,PSIP1,MAN1B1,DIPK1A,SLC35G1,METTL21A,KCNC1,KLRC2,A1BG-AS1,GPR155,MAN2A2,MEF2C,MEIS1,KITLG,MKLN1,MYO9A,PABPC1L2A,NF1,HCN1,OXTR,ZNF827,PBX1,GPR85,CYTL1,ST8SIA5,PMS2,TNPO2,POLG,MED1,MAPK4,QRICH1,PXK,TMEM260,PPP2R3C,PID1,OXR1,RADX,SLC6A15,FIGN,YY1AP1,RPL15,SPIN3,MCMBP,ATAT1,KCNIP3,SEMA6D,CSRNP3,ITSN1,SHMT2,CHD9,CCDC92,LRRC55,SLC8A2,SEPHS1,CCDC88A,MTERF2,BTBD7,SLIT1,SLN,KDM4B,DOP1A,MYT1L,ZNF423,DBNDD2,LARP4,SSPO,STAU1,ZSCAN29,COBL,C12orf76,DDHD2,ZFP90,TCF7L2,FRYL,AHCYL2,PMS2CL,KCTD2,TPD52,TRH,ZMYND8,FAM155A,VSNL1,ZBTB14,ZNF142,STOX2,PPP1R3F,KCNAB1,PLSCR4,UBE3B,TTC7A,FRMD6,CBLN2" MicroRNA hsa-miR-576-5p:PITA hsa-miR-576-5p:PITA_TOP PITA 1.34E-69 7.55E-66 5.56E-69 5.12E-68 137 434 "FMNL2,CCDC85A,PCDH19,HACE1,SRPX,DPP10,EPB41L5,DGKD,PPP4R4,ARHGAP5,DDX3Y,SLC4A4,DOCK11,MPDZ,DCAF5,CDK5R1,CA8,MAP7,CLGN,KMT2C,KIAA1549L,NRXN1,QKI,MAP4K4,ARMC8,ABI3BP,CREB5,CNTNAP2,ERC2,KIAA0408,TOX,PHF19,DGKB,ZEB2,RHOBTB1,WDR20,DLG2,RAB39B,CPEB2,DSCAM,DYRK1A,ANKRD46,TENM1,ERBB4,CLVS1,FABP7,FGF1,SUCO,AFF2,TMEM107,PHYHIPL,MEGF11,NCKAP1,FAXC,PCDH17,TOX3,FUT10,GRB10,IL1RAPL1,SOX21,ZHX1,HNF4G,NEGR1,IGF1,ZIC5,ITGAV,KCNA4,CLVS2,KCNMA1,ARHGAP12,MAP2,MBNL1,SCG3,MYO5A,NCAM2,NEUROD1,CNOT4,CNTN3,PCSK2,CCSER2,XRN1,PLCL1,EPN1,FAT3,PKIA,PKN2,SYTL2,PTCH1,PTPRE,USP47,RFX2,UBR7,RGS7,ZFHX4,ZNF532,RYR3,SOX6,TRA2B,SCG5,ZFP30,CHD9,FNDC3A,WDR47,MYT1L,SP4,ARHGAP26,KIF1B,ITPRID2,LARP4,KLHL7,NECAB1,C3orf70,ANKRD28,CAMSAP2,ZEB1,RPGRIP1L,PUM2,FRYL,AP4E1,ZNF106,RIMBP2,TP53BP2,STXBP4,LYPD6,ZBTB38,PMEPA1,PRTFDC1,SLC38A1,WNK3,SLC17A6,PDSS2,RGS7BP,DNAH10,KAT6A,HNRNPA3,SOCS4,SENP7" MicroRNA hsa-miR-522:PITA hsa-miR-522:PITA_TOP PITA 1.48E-69 8.30E-66 6.10E-69 5.62E-68 147 503 "CLK4,USP31,BEND6,MTA3,CASKIN1,OSBPL6,TAOK1,BCAR3,LRCH2,ARHGAP5,ASCL1,MTMR9,FGF17,CANX,TMEM257,EVI5L,NUMBL,CACNA2D2,FOXN3,SOCS6,KMT2C,CNTFR,AKAP6,FGFR1OP2,HDAC4,TOX,DGKB,ARMCX2,MYEF2,ZC3H11A,SNAP91,DLG2,NR1D2,SLC12A6,DNAJB6,DYRK1A,ST8SIA3,EDNRA,RBM12,APH1A,ABI2,EGR3,PLEKHA1,EIF1,ETV1,RTN3,EZH1,ACSL4,DLC1,OLFM1,PRKAG2,SUCO,SYNCRIP,NBEA,CSPG5,OGA,PHYHIPL,AHCYL1,PCDH17,PPARGC1A,TNRC6A,KDM2B,INSM2,GNAO1,CECR2,ZHX1,BACH2,MIER3,HNRNPK,TLX1,HTR2A,IDH3A,DOCK7,KCNA1,KCNK2,KIT,STMN1,MBNL1,LRP1B,MEF2C,KITLG,MYO5A,HNRNPM,NCAM1,NEUROD1,NFE2L2,HCN1,TBC1D25,PDGFRA,TNPO2,PPP2R5E,SNRK,FAM120C,RDX,KIF7,ZNF532,ALG9,CCDC25,SALL1,FAM19A1,FNIP1,GALNT10,SGK1,KIF21A,PPP1R9A,PPM1E,CPEB3,SHC4,WDR37,SLC1A3,RUFY2,SLC12A2,RCOR3,SNAP25,SNCA,WDTC1,NMNAT2,HECW1,MYCBP2,LMO3,SRPK2,TAB2,ATP11A,TCF4,RPGRIP1L,SZT2,PSD3,NSD1,SIRT1,KAT6B,RBFOX2,TPM3,ZNF384,CADM1,FAM155A,UBE3A,NSD2,CLDND1,PCDH20,ZIC1,KCNT2,LYPD6,MAP3K12,CSDE1,HNRNPA3,FRMD6,NETO2" MicroRNA hsa-miR-637:mirSVR_highEffct hsa-miR-637:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-69 8.68E-66 6.38E-69 5.88E-68 160 598 "ARID1A,NDRG2,KLHL32,DSCAML1,ADD2,CASKIN1,KIAA1324,CC2D2A,PKP4,ANXA7,CNTNAP1,UPRT,PCDHGB4,TTLL9,CASTOR3,CACNA1G,KALRN,BRSK2,LGI1,PPT2,NRXN2,PICK1,SUMF2,LETMD1,AKAP5,SMARCAL1,MYRIP,CPS1,SEC31B,CLIP3,SEC24C,FEZ1,CSNK1G3,NRSN1,CX3CR1,DCAF8,DGKG,RUSC2,AK5,SGSM2,DPH1,DTNB,DUSP9,AASDH,EFNA3,RASA4,IRAK4,CERCAM,COQ7,DMTN,ERCC2,CDKL3,CLVS1,ST3GAL6,STRADA,FGF11,FGF14,FLT1,APOPT1,USP21,CELF1,ACSS1,MYOZ2,NEU3,GCK,GLYR1,STARD3,GPD2,FUT10,LILRA2,PLCD4,GRIK5,GRM3,GRM7,RNF165,ADAMTS6,ATXN2L,KLF12,AGBL5,CFAP126,LRRC75A,IDH3A,SCRT2,KCNJ9,MBD1,GIT1,CTNNA3,MYO9A,RTL5,IGSF11,PCDHGC3,PCSK5,NLGN3,PLCB2,PLTP,EPB41L4B,PILRA,CRLS1,PPP5C,PIGG,PEX5,RAD51D,RFX4,EXD2,PRR5L,ATAT1,SELL,ARX,FERMT1,ASAP3,FUZ,R3HDM2,SMTN,RAB3GAP1,NAPB,INAVA,UNC5B,TSPYL2,POGZ,SSPO,INKA2,ZSCAN29,KANK1,SULF2,GANAB,SEPT3,KLHL7,ARC,SYT4,CAMTA1,ANO4,TCF4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RALYL,ARHGAP9,THRA,MTMR14,DDHD1,TPD52L2,NUTM2A,RPL7L1,WNT7A,TRIM9,GPR158-AS1,SMARCAD1,PCDH15,ITM2C,RNF170" MicroRNA hsa-miR-300:PITA hsa-miR-300:PITA_TOP PITA 1.78E-69 1.00E-65 7.34E-69 6.76E-68 150 525 "CCDC85A,SNX30,GPR158,TRMT9B,LRFN1,CDC42BPA,ANK3,EPB41L5,DGKD,EIF4G3,STX16,CARMIL3,CACNB2,KALRN,LDB2,KMT2C,NRXN1,CNR1,ARMC8,ACBD5,ZNF521,CREB5,CLIP3,OSBPL3,CSNK1G3,SOCS5,PLCXD3,DOCK4,ARHGAP24,YTHDC1,ZC3H11A,FAM107B,RAB39B,DMTF1,SLC12A6,DPP6,DYRK1A,ST8SIA3,SNX29,FAM135B,MBNL2,KMT5B,EIF4G2,EML1,PAN3,EIF1,VPS13B,EPB41,EPB41L1,KCNMB2,SRRM1,EPS8,DLC1,FOXF2,SYNCRIP,FOXO3,NBEA,SORBS1,MEGF10,CHL1,GABRB3,RAPGEF6,NCKAP1,C15orf41,GFRA1,PCDH17,PCDH11X,ADGRA3,PSIP1,KLF12,MIER3,ZIC5,RBPJ,JAK2,KCNA4,KCND2,STXBP5,MARK1,MBNL1,MEIS2,MID1,MITF,AFF1,NEXMIF,NAP1L2,ZC3H12B,NEUROD1,NFIA,CNOT4,HCN1,PCDH8,PCSK2,PENK,KCTD15,PURG,PMP22,PRRX1,KANSL1,CEP41,SNRK,PTCH1,PTK2,RAP1GDS1,ZNF532,SALL1,SEMA6D,SATB1,FNIP1,SFPQ,SCAF8,PPM1E,CHD9,R3HDM2,WDR37,ABLIM3,SLC1A2,SLC6A8,RIMS1,SOX2,SP4,RBM26,EPB41L3,LARP4,LRRC4,VAMP1,POPDC3,ANKRD12,ANO4,TCF4,WDR7,CRTC1,FRYL,ZFPM2,NACC2,R3HDM1,KAT6B,TP53BP1,UBE3A,USP1,TBC1D15,VSNL1,ZBTB38,EMSY,NAV3,SNX27,KAT6A,PHTF2,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-381:PITA hsa-miR-381:PITA_TOP PITA 1.78E-69 1.00E-65 7.34E-69 6.76E-68 150 525 "CCDC85A,SNX30,GPR158,TRMT9B,LRFN1,CDC42BPA,ANK3,EPB41L5,DGKD,EIF4G3,STX16,CARMIL3,CACNB2,KALRN,LDB2,KMT2C,NRXN1,CNR1,ARMC8,ACBD5,ZNF521,CREB5,CLIP3,OSBPL3,CSNK1G3,SOCS5,PLCXD3,DOCK4,ARHGAP24,YTHDC1,ZC3H11A,FAM107B,RAB39B,DMTF1,SLC12A6,DPP6,DYRK1A,ST8SIA3,SNX29,FAM135B,MBNL2,KMT5B,EIF4G2,EML1,PAN3,EIF1,VPS13B,EPB41,EPB41L1,KCNMB2,SRRM1,EPS8,DLC1,FOXF2,SYNCRIP,FOXO3,NBEA,SORBS1,MEGF10,CHL1,GABRB3,RAPGEF6,NCKAP1,C15orf41,GFRA1,PCDH17,PCDH11X,ADGRA3,PSIP1,KLF12,MIER3,ZIC5,RBPJ,JAK2,KCNA4,KCND2,STXBP5,MARK1,MBNL1,MEIS2,MID1,MITF,AFF1,NEXMIF,NAP1L2,ZC3H12B,NEUROD1,NFIA,CNOT4,HCN1,PCDH8,PCSK2,PENK,KCTD15,PURG,PMP22,PRRX1,KANSL1,CEP41,SNRK,PTCH1,PTK2,RAP1GDS1,ZNF532,SALL1,SEMA6D,SATB1,FNIP1,SFPQ,SCAF8,PPM1E,CHD9,R3HDM2,WDR37,ABLIM3,SLC1A2,SLC6A8,RIMS1,SOX2,SP4,RBM26,EPB41L3,LARP4,LRRC4,VAMP1,POPDC3,ANKRD12,ANO4,TCF4,WDR7,CRTC1,FRYL,ZFPM2,NACC2,R3HDM1,KAT6B,TP53BP1,UBE3A,USP1,TBC1D15,VSNL1,ZBTB38,EMSY,NAV3,SNX27,KAT6A,PHTF2,ST8SIA2,CPNE4,JPH3" MicroRNA hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA_TOP PITA 2.06E-69 1.16E-65 8.47E-69 7.80E-68 135 422 "ARID1A,CCDC85A,HACE1,OSBPL8,SPARCL1,ARHGAP20,DPP10,ANK3,API5,USP37,PPP4R4,NUMB,ASTN1,RNF182,CALB2,RUNX1T1,LDB2,REPS2,ZMYM4,FOXN3,CHGA,KMT2C,NRXN1,TMEM184B,CNR1,GDA,CLIP3,ERC2,PLCXD3,GAPVD1,SNPH,FRMPD4,HDAC4,DAPK1,ZEB2,CEP170,MAGI2,ZC3H11A,POM121,SMG7,SGSM2,G3BP2,DLG2,HS3ST4,DYRK1A,PHC2,YAF2,FAM13A,ELAVL2,ETV1,DLC1,ATP8A1,FGF13,CAMSAP1,UBE2E3,CAP2,FOXO3,SGIP1,SORBS1,GAD2,CPLX2,SRCAP,PPARGC1A,TOX3,TNRC6A,GPM6A,STMN2,GRID1,NR3C1,KAT7,WIF1,BACH2,NEGR1,SMAP1,ZIC5,SCRT2,STXBP5,MEIS2,AFDN,HS6ST3,ZC3H12B,HCN1,CNTN3,PDE4D,GPR85,OLA1,CDK14,PIK3C2A,PURG,PRRX1,EPB41L4B,PACSIN1,NXPH1,KANSL1,CEP41,PROX1,MTMR10,PTPRB,PTPRD,PEX5,RFX3,RNF220,ZNF532,CARF,LRRK2,KIF21A,EPN2,YPEL4,SLC8A1,PDZD2,KIF21B,SOX11,RBM26,NKAIN2,PRRC2C,SYNE2,C3orf70,PLCB1,SYPL1,SYT4,TAC1,TBX15,TRIM2,WDR7,PUM2,SIRT1,TBC1D15,ZIC2,REEP1,ZFAND5,WNK1,EVI5,HNRNPA3,ACTR3B,RNF146" MicroRNA hsa-miR-516a-3p:mirSVR_highEffct hsa-miR-516a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.39E-69 1.34E-65 9.84E-69 9.07E-68 192 857 "KLHL32,SLITRK1,GALNT13,SORCS1,KIAA1211,ALAD,AMPD3,ZFAT,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,ARSF,NUMB,ATP1A2,ATP6V0A1,NAE1,WASF1,MMD2,CFAP410,VSTM2A,CAST,RUNX1T1,CCNH,AP4M1,ZBED1,CCPG1,CFL2,NDST3,IGFBP7-AS1,CLCN3,COL9A3,MYRIP,CSNK1G3,DZIP3,PHF14,RIMS2,DCAF4,MYADM,ZFYVE16,DAPK1,BRINP1,HEPH,ZNF582-AS1,DMD,DOCK2,DPP6,DTNA,EDIL3,KLHL5,PHF20L1,MBNL2,PCOLCE2,DCTN4,LRRC17,RABEPK,STX2,GMPR2,F3,NSRP1,RPS6KC1,ATP5PD,MEX3B,FLNC,SLC37A3,NOP56,SMC2,HVCN1,KHDRBS3,FAM120B,RAPGEF6,GFRA2,HEPN1,GHR,ZNF638,GOLGB1,GPD2,GPM6B,TDRKH,PRLHR,CCDC184,PCLO,STMN2,GRIA2,GRIA4,HAS2,LINC01102,AGBL5,HSF2,USP54,ZNF385B,KCND2,KCNN2,KLC1,LAMP2,PAXBP1,PACRG,MAP4,AQP11,SYT9,LDLRAD3,CTNNA3,RSPO2,NAP1L3,NCAM1,IDNK,OLR1,PAK3,PDE1A,PDE4B,PDGFRA,ZNF655,PLCL1,SEPT4,MBOAT7,PPARA,CRLS1,PPP2R5C,PPP2R5E,APTX,TMEM260,PTPRE,PTPRN2,PLEKHB2,GTDC1,RGS12,ELP2,MRAP2,ACER3,STK32B,LRRK2,ZNF354C,AP1AR,S100B,HOGA1,FAM19A1,TNFRSF19,CASC3,SFPQ,SH3GL2,MAGI3,SLITRK3,ZNF365,CCDC88A,SLC15A2,BTBD7,TET1,SMARCE1,UNC80,MYT1L,PEG10,KIF1B,NFASC,STOX1,ZC4H2,DIP2A,SYT1,SYT4,ASTN2,ANKRD12,MCF2L,AGTPBP1,TBL1X,DMXL2,SATB2,ZEB1,TPCN2,CLASP1,FRYL,FAM200B,THBS4,CDH22,TMEM9,TLR4,NR2E1,TMPO,RIMBP2,TNR,STXBP4,TTC3,HIRA,PLEKHH2,CCDC14,KCNT2,ZNF189,SLC30A4,LMAN2L,MDH1B,PCDH15,PARP11,KAT6A,NETO2" MicroRNA hsa-miR-516b*:mirSVR_highEffct hsa-miR-516b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.39E-69 1.34E-65 9.84E-69 9.07E-68 192 857 "KLHL32,SLITRK1,GALNT13,SORCS1,KIAA1211,ALAD,AMPD3,ZFAT,PHF12,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,ARSF,NUMB,ATP1A2,ATP6V0A1,NAE1,WASF1,MMD2,CFAP410,VSTM2A,CAST,RUNX1T1,CCNH,AP4M1,ZBED1,CCPG1,CFL2,NDST3,IGFBP7-AS1,CLCN3,COL9A3,MYRIP,CSNK1G3,DZIP3,PHF14,RIMS2,DCAF4,MYADM,ZFYVE16,DAPK1,BRINP1,HEPH,ZNF582-AS1,DMD,DOCK2,DPP6,DTNA,EDIL3,KLHL5,PHF20L1,MBNL2,PCOLCE2,DCTN4,LRRC17,RABEPK,STX2,GMPR2,F3,NSRP1,RPS6KC1,ATP5PD,MEX3B,FLNC,SLC37A3,NOP56,SMC2,HVCN1,KHDRBS3,FAM120B,RAPGEF6,GFRA2,HEPN1,GHR,ZNF638,GOLGB1,GPD2,GPM6B,TDRKH,PRLHR,CCDC184,PCLO,STMN2,GRIA2,GRIA4,HAS2,LINC01102,AGBL5,HSF2,USP54,ZNF385B,KCND2,KCNN2,KLC1,LAMP2,PAXBP1,PACRG,MAP4,AQP11,SYT9,LDLRAD3,CTNNA3,RSPO2,NAP1L3,NCAM1,IDNK,OLR1,PAK3,PDE1A,PDE4B,PDGFRA,ZNF655,PLCL1,SEPT4,MBOAT7,PPARA,CRLS1,PPP2R5C,PPP2R5E,APTX,TMEM260,PTPRE,PTPRN2,PLEKHB2,GTDC1,RGS12,ELP2,MRAP2,ACER3,STK32B,LRRK2,ZNF354C,AP1AR,S100B,HOGA1,FAM19A1,TNFRSF19,CASC3,SFPQ,SH3GL2,MAGI3,SLITRK3,ZNF365,CCDC88A,SLC15A2,BTBD7,TET1,SMARCE1,UNC80,MYT1L,PEG10,KIF1B,NFASC,STOX1,ZC4H2,DIP2A,SYT1,SYT4,ASTN2,ANKRD12,MCF2L,AGTPBP1,TBL1X,DMXL2,SATB2,ZEB1,TPCN2,CLASP1,FRYL,FAM200B,THBS4,CDH22,TMEM9,TLR4,NR2E1,TMPO,RIMBP2,TNR,STXBP4,TTC3,HIRA,PLEKHH2,CCDC14,KCNT2,ZNF189,SLC30A4,LMAN2L,MDH1B,PCDH15,PARP11,KAT6A,NETO2" MicroRNA hsa-miR-218-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.09E-69 1.74E-65 1.27E-68 1.17E-67 187 816 "ACTN1,ARID1A,AP2A2,ZNF608,KLHL13,HFM1,LTBP4,ZFAT,CDC42BPA,ANK3,PKP4,APC,DGKZ,SHROOM2,CCDC74A,ATM,EIF4G3,DCAF5,KSR1,DST,FUBP1,SCAPER,MTMR3,FOXK1,SPAG9,CDH2,LRRFIP1,SLIT2,FADS2,SUMF2,BTF3L4,RCHY1,LRIG1,VCAN,CNTNAP2,SDC3,PNPLA8,DCAF8,PHF19,EARS2,INTS1,IST1,DAPK1,SCRN1,GIT2,ELMSAN1,ZBTB24,HP1BP3,FBXL5,BLOC1S6,POM121,SACS,SEC16A,DMTF1,PHC2,EEF1D,EGFR,MBNL2,RASA4,EIF4G1,OLIG2,KATNAL1,FAM198B,FOXO3,SEMA4D,ANKFY1,NPTN,ATP6V1H,HBS1L,SALL3,SRRM4,WASF3,CSDC2,KIRREL3,RNPS1,GLI2,RAB30,CBX1,GNAS,FERMT2,GOLGB1,GPM6A,ZNF496,KLF12,HMGB1,EID2B,MSL1,SHISAL1,RBPJ,ITGAV,KCNMA1,KIT,IPO5,HECTD2,MBNL1,MEIS2,MID1,MITF,MMP16,CCDC80,MTR,DNHD1,SLC11A2,KSR2,ZNF827,PDGFRA,SSH1,PKM,SH3KBP1,PPP2R5E,PRKAR1B,CNNM2,QRICH1,PTCH1,MTMR10,PTPRG,RIPOR1,USP47,SUSD4,RET,REV3L,RFX5,UBR7,MRPS18A,SLC25A36,ROBO1,RPL15,GLDN,LGR4,ZNF354C,SATB1,ATXN1,FNIP1,SFPQ,PUF60,DOCK10,ST6GAL1,SEC31A,CLSTN1,SEPHS1,BTBD7,SLC20A2,EPC1,COA1,PALLD,KIF21B,UNC5B,ZC3H13,SS18,MPRIP,STAU1,SULF2,SYT11,ZC3H4,PRRC2C,CAMTA1,SATB2,USP22,DOCK9,PSD3,NSD1,PUM2,DICER1,TGFBR3,ZFP91,PARD3,TPD52,TPM3,CHST5,TRPS1,UBE2H,UCHL1,VAV2,CLIP2,RICTOR,ZNF711,SPIRE1,TFIP11,SLC38A1,HPS4,ITM2C,WIPF2,HNRNPA3,NUP214,RNF170,NHSL1,AAAS" MicroRNA hsa-miR-3135:mirSVR_lowEffct hsa-miR-3135:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.44E-69 1.93E-65 1.41E-68 1.30E-67 204 963 "TMEM132B,GALNT16,ADCY6,AXIN2,USP31,MTUS1,CC2D2A,ADGRF5,BCAR3,LCORL,PHF12,APBB1,BCAS1,MIER1,KIAA1614,ZFYVE28,CADPS,ZSCAN18,RASL11B,ASTN1,ALDH4A1,ATM,RNF182,SNAI3-AS1,DCAF5,CACNA1G,CA8,ISPD,CCNH,USP6,P2RX6,ENTPD2,LRBA,SEPT7,CDH2,MAGI1,CPNE6,FBXO7,ABI3BP,FAM171B,SEC31B,SEC24C,ARHGEF10,MICAL2,CMTM5,PNPLA8,RIMS2,CCDC144A,ARHGAP32,TCAF1,KIAA0586,GIT2,SIRPA,YTHDC1,RUSC2,FBXO25,GUCD1,DLG4,DLX1,DMTF1,DPP6,DRP2,GNE,ABCC9,E2F5,FAM135B,EEF1A2,CNNM1,TMTC1,YAF2,CELSR3,MRNIP,VPS13B,LRRC23,RASL12,REEP2,NSRP1,TUBB3,FCGR1A,FCGRT,ZNF589,SEC24B,AGAP2,FLT1,DCTN2,KHDRBS3,ST6GALNAC3,STAU2,TUBGCP4,SRCAP,USP19,PPARGC1A,STARD3,LILRA2,RAPGEF4,GRM7,GSTM5,RASSF8,HPS5,PTGDR2,HRH3,MIER3,HSD17B1,EID2B,INPP5B,SLC35G1,KCNA1,KCNK2,STXBP5,SMAD1,MBNL1,ADAM11,MDFI,SCAMP5,BLOC1S2,MYH6,HNRNPM,NDUFA5,NF1,OCRL,OPA1,P2RX7,PCMT1,PDE4D,GNG2,BEST3,PFKFB2,SEMA5B,CAMKV,TMIE,A2ML1,FTO,PLXNB1,RC3H2,PILRA,PPM1B,CRLS1,PRKACB,BDNF-AS,PTHLH,SLC25A41,ENOX1,RGR,RGS12,SETD5,EPHA10,ADAL,LRRK2,PAQR6,MAPK12,TNFRSF19,ASAP3,MAGI3,AMBRA1,SEPHS1,SLC9A5,SLC11A1,SLC15A2,ELMO2,RCOR3,ANKRD36,LIMCH1,PALLD,WDTC1,TSNAXIP1,TAB2,CLSTN2,POGZ,NKAIN2,TACC1,ACSL6,SIN3B,CUX2,NAT16,TF,LEFTY2,SLC44A1,ENHO,TNFRSF1B,TPM2,SMUG1,ELP5,TRPM2,SGK3,CLEC2L,GORASP1,XRCC4,LGI4,ZIC2,ATP6V0E2,GPR158-AS1,SH3GLB2,NT5M,GDPD5,LINC02210,HPS4,SLC17A7,LINC00632,DOCK8,CASC15,TRAM2-AS1,TIGD6,VANGL2,AP3B2" MicroRNA hsa-miR-520f-3p:TargetScan hsa-miR-520f-3p TargetScan 3.69E-69 2.07E-65 1.51E-68 1.39E-67 145 492 "ABR,ADD1,MTUS1,HECW2,KCTD16,OSBPL8,PCDH10,ANK2,APBB2,APP,MIER1,EIF4G3,ATP2B2,DST,ARHGEF7,MTMR3,JAZF1,MYRF,PTBP2,PRC1,FMNL3,CDC25B,CDH2,LGI1,MAGI1,CFL2,ARMC8,LETMD1,IFFO1,ACBD5,IGDCC3,CLOCK,CREB5,GREB1,KIAA0513,RASSF2,DGKB,DLG3,HS3ST4,ABCC5,EDNRB,FSD1L,MBNL2,PLXNC1,PAN3,EMX2,ERBB4,DNAJC27,EZH1,CACNG3,EFEMP1,ATP8A1,MED12L,CAMSAP1,POLK,FLT1,MSANTD4,NCKAP1,FAXC,GLUL,MAP7D2,LUZP2,GPR37,PTPRT,IL1RAPL1,FAM222A,BACH2,RBPJ,IL6ST,JAK1,OLFM3,KCNB1,MARK1,MBNL1,MEF2C,MXI1,NFIA,NFYA,NOVA1,NPTX1,HCN1,OCRL,OPCML,GPR137C,KCNK10,PAK3,PDE3A,CDK14,CCSER2,LRP12,FAT3,CRLS1,PPP3CA,PKIA,PKN2,APTX,MDGA2,PTPRD,ARID4A,RDX,FIGN,ALG9,CYB561D1,RIMKLA,LGR4,RXRA,AMER2,ATXN1,ATXN7,MYO18A,FNDC3A,EPC1,ARHGAP26,IQSEC2,CDK19,LMO3,NXT2,RGL1,ACSBG1,FGD4,ARHGEF9,PLCB1,ANKRD12,CAMSAP2,FBXW11,CUX2,NSD1,LEFTY2,DDHD1,PIK3R5,RBFOX2,RGMB,NR2C2,FRRS1L,RICTOR,LYPD6,LAMP5,CADM2,LRP8,RGMA,PRDM8,PRDM10,FAM13C,ADAMTSL3,NETO1" MicroRNA hsa-miR-302c-3p.2:TargetScan hsa-miR-302c-3p.2 TargetScan 3.69E-69 2.07E-65 1.51E-68 1.39E-67 145 492 "ABR,ADD1,MTUS1,HECW2,KCTD16,OSBPL8,PCDH10,ANK2,APBB2,APP,MIER1,EIF4G3,ATP2B2,DST,ARHGEF7,MTMR3,JAZF1,MYRF,PTBP2,PRC1,FMNL3,CDC25B,CDH2,LGI1,MAGI1,CFL2,ARMC8,LETMD1,IFFO1,ACBD5,IGDCC3,CLOCK,CREB5,GREB1,KIAA0513,RASSF2,DGKB,DLG3,HS3ST4,ABCC5,EDNRB,FSD1L,MBNL2,PLXNC1,PAN3,EMX2,ERBB4,DNAJC27,EZH1,CACNG3,EFEMP1,ATP8A1,MED12L,CAMSAP1,POLK,FLT1,MSANTD4,NCKAP1,FAXC,GLUL,MAP7D2,LUZP2,GPR37,PTPRT,IL1RAPL1,FAM222A,BACH2,RBPJ,IL6ST,JAK1,OLFM3,KCNB1,MARK1,MBNL1,MEF2C,MXI1,NFIA,NFYA,NOVA1,NPTX1,HCN1,OCRL,OPCML,GPR137C,KCNK10,PAK3,PDE3A,CDK14,CCSER2,LRP12,FAT3,CRLS1,PPP3CA,PKIA,PKN2,APTX,MDGA2,PTPRD,ARID4A,RDX,FIGN,ALG9,CYB561D1,RIMKLA,LGR4,RXRA,AMER2,ATXN1,ATXN7,MYO18A,FNDC3A,EPC1,ARHGAP26,IQSEC2,CDK19,LMO3,NXT2,RGL1,ACSBG1,FGD4,ARHGEF9,PLCB1,ANKRD12,CAMSAP2,FBXW11,CUX2,NSD1,LEFTY2,DDHD1,PIK3R5,RBFOX2,RGMB,NR2C2,FRRS1L,RICTOR,LYPD6,LAMP5,CADM2,LRP8,RGMA,PRDM8,PRDM10,FAM13C,ADAMTSL3,NETO1" MicroRNA hsa-miR-3170:mirSVR_highEffct hsa-miR-3170:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.95E-69 2.22E-65 1.62E-68 1.49E-67 193 868 "ABHD6,SLC12A5,PLEKHH1,OSBPL1A,CC2D2A,MYH7B,DGKZ,SHTN1,AQP6,INSYN2B,N4BP2L1,NOL4,CAMK2G,RUNX1T1,CCKBR,AIFM1,DGKI,ZMYM4,TIGD7,CFL2,SRSF11,JAM2,SLC22A6,CPNE6,NRXN3,TPP1,MYL6B,FAM19A5,QKI,CNGA3,CNR1,COL9A1,SLC4A7,ZNF521,SLC35F1,SEC31B,HINFP,C1QL2,GDA,CLIP3,CSF2RA,PLXNA4,APPL1,RIMS2,RUBCN,EDRF1,CYBB,FGFR1OP2,TCAF1,ARMCX4,HEPH,CNIH3,COPS7A,RHOBTB1,SNAP91,SV2B,CHRDL1,DLX1,DMD,DMPK,GNE,GOLT1B,AASDH,EDNRA,PHF20L1,MBNL2,EMX2,ANKRD13B,IGSF6,ETV1,F8,ABCA8,ST3GAL6,GORAB,FGF13,FGFR1,TMEM164,MEX3B,HPCAL4,TMEM107,DACH2,STAU2,GABRA3,FAM184B,DISC1,ADAM28,PCDH17,CRCP,DBF4,GLS,TNRC6A,GLUL,GRIA2,GRIK2,SPACA9,GRIK5,BVES,RNFT2,HMGCL,SMAP1,LRRC25,TJAP1,IL6R,LRRTM1,KIF5A,KIF5C,LAMA2,ARHGAP12,POC1B,MOBP,MOG,MSRA,IDNK,NF1,NFIX,VWA2,CNOT4,PCSK5,PCSK2,TMEM38A,PURG,PMP22,TATDN3,PKIA,MAPK3,GDPD1,MASP1,SNRK,PTAFR,PID1,TMEM255A,OXR1,BSDC1,ZMAT4,RFX4,UBR7,RNASEL,CCDC82,CARF,YY1AP1,ATP8B4,ACER3,ATAT1,SEMA6D,TNFRSF19,ITSN1,ARX,SHC4,MAGI3,FHOD3,FAM81A,DHX30,SLC8A1,CCDC88A,SLC14A1,ATF7IP,SORCS3,SON,PDZD2,EMC1,TSPYL2,TAB2,PBLD,SEPT8,SULF2,NECAB1,SYN1,TAC3,MLST8,TCF4,PCDHB15,TNS2,CCDC173,ZMAT3,SLC44A1,ARL10,TIMP4,SEZ6L,IL34,TRH,ZMYND8,SLC35A4,PLEKHH2,ZNF709,BCL2L13,NSD2,NDRG4,ZNF138,ZBTB38,EMSY,SIGLEC10,FAM13C,RNF170" MicroRNA hsa-miR-876-3p:mirSVR_highEffct hsa-miR-876-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.97E-69 2.23E-65 1.63E-68 1.50E-67 179 751 "KCNH8,NBAT1,TKTL1,ARID1A,CDC7,SORCS1,SLC24A4,HACE1,KIAA1324,LTBP4,FAM135A,ANK3,ALS2,LGR5,ARHGAP5,BRINP2,STX16,RGS9,CALM1,CAMK2G,INA,DGKI,TIGD7,CHN2,QKI,FAM149A,COL4A5,PNKD,SIPA1L1,PLXNA4,APPL1,PHF14,GREB1,ZSCAN23,FGFR1OP2,FRMPD4,PHYHIP,DCC,DNAJC6,ZC3H11A,ALKBH8,DLG2,DMD,SLC25A18,TOM1,ANKRD46,KLHL5,PHF20L1,APH1A,EGFR,MBNL2,PLEKHA1,ELN,EPHB1,TMEM74,ST3GAL6,FCGR3A,ZSCAN30,KAT8,GORAB,FGF12,FOXF2,RGPD5,ARFGAP2,NSG1,OGA,GABRA3,BRPF3,BRD8,DBF4,GNAS,GPM6B,RAPGEF1,GRIN2C,CIT,FAM107A,LRRCC1,IL6R,NME9,ITIH2,SLC35G1,OLFM3,KCND2,KCNJ3,KCNJ10,KCNN2,LIMS1,NCOA7,MDM4,MEIS1,SCG3,NUCB2,OLR1,GLIPR1L2,PCMT1,PDCD2,GNG2,GDAP1L1,FAM216A,PLIN1,SLC25A23,PURG,PACSIN1,TATDN3,RANBP3L,PRKACB,PRKCZ,MASP1,BCAS3,WBP1L,MDGA2,PTAFR,TMEM260,PTPRD,PEX2,CCDC40,SH3TC2,ZCWPW1,RBBP6,BSDC1,RDX,ZMAT4,RFX4,KCNIP1,ATXN7,SCN3A,LRRTM4,SCN8A,SMPD3,GALNT10,COPZ1,SGK1,ITSN1,MAGI3,ST6GAL1,PAAF1,SLA,ZNF365,SMTN,SLC6A1,SLC14A1,ZFP1,SORCS3,ANKRD36,SNAP25,SNRPN,PALLD,PDZRN3,UNC80,KDM4B,TEX2,NFASC,TAB2,PBLD,POGZ,ITPRID2,LRRC4,KANK1,FAM168A,SYNE2,SYP,SLC37A2,CLASP1,PCDHB3,FAM200B,SLC44A1,ERCC6L2,C5orf64,NPL,PDSS1,PPIL6,UBTF,USP1,CFAP298,PCBP1-AS1,MFF,PCDH15,NAV3,WIPF2" MicroRNA hsa-miR-18b*:mirSVR_lowEffct hsa-miR-18b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.29E-69 2.41E-65 1.75E-68 1.62E-67 176 727 "SDE2,CSMD2,XKR4,PWWP2A,ADRB2,CC2D2A,ZNF578,ARHGAP20,MARCH4,PPFIA1,PARG,APC,SHROOM2,CDK13,ASPH,NUMB,EIF4G3,ATP1B3,ATP2B1,N4BP2L1,NOL4,ADAM15,BCL2L2,IL33,CAST,ISPD,SPAG9,CDC25B,SRSF11,NRXN3,TJP2,COL11A2,SLC4A8,MYRIP,SEC24C,FEZ1,CSNK1E,SIPA1L1,NCAN,SLITRK5,SDC3,PLCXD3,ECE2,LIN54,ELMSAN1,TIAM2,BLOC1S6,PARD6A,CCDC3,DLX1,DMD,DRD1,TMTC1,PHF20L1,IRAK4,USPL1,EPB41,EYA1,FCGR1A,TOMM40L,TESK2,IQCG,EVL,SMC2,STAMBP,ZNF605,PNMA2,GABRB1,GABRG1,B4GALNT1,IP6K3,ERAP1,MTHFD2,LRRC37A6P,WASHC2A,SPIN1,ZNF638,PRUNE2,PLPP7,ZNF496,GUCY1B1,ATOH8,CELF3,MAEL,PADI2,NCKAP1L,ELOVL5,ZDHHC15,FAM95B1,RBPJ,PLD5,SLC6A17,ITGAM,KCNMA1,STXBP5,PAXBP1,MEF2C,MMP16,MYO9A,FXYD6,SFR1,PCBP3,CNTN3,BEST3,PIK3R1,XRN1,PKM,PPP2R5E,HYDIN,ANKHD1,PTHLH,PTPRB,PEX2,MARCH1,RBBP6,SLC6A15,RNASE1,PNMA8A,CCDC102B,SOX8,RMI1,STUM,ZFP30,KIF21A,SHMT2,FHOD3,ST3GAL3,PPP4R3A,EPN2,KANSL3,YPEL4,BTBD7,ZNF667,SON,ZC4H2,SEPT8,GANAB,ARHGEF9,VPS13A,NUDT10,ANKRD28,FAM208A,TMEM136,DMXL2,DOCK9,CRB1,AP4E1,TGFBR3,ZNF106,ZFP91,DAAM2,CSMD1,C5orf64,RBFOX2,ZNF346,SYNPO2,PPIL6,TTTY15,RPRM,BEST1,CLIP2,XPO1,XRCC4,ZNF711,ZNF32,FMN2,ZNF184,DHX33,EVI5,STOX2,NAV2,MPPE1,WNK2,PHTF2,NUP214,ZNF248" MicroRNA hsa-miR-1321:mirSVR_highEffct hsa-miR-1321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.86E-69 2.73E-65 1.99E-68 1.83E-67 189 835 "VWA5B2,ADAR,ADARB2,SORCS1,KLHL13,AK2,SPOP,ZNF687,LRFN1,OGT,LCORL,TMEFF1,ARHGDIG,TMEM108,ATP6V1G2,MYOM1,CFAP410,RUNX1T1,ARHGEF1,MAGI1,SLC22A6,NRXN2,COG1,QKI,ARHGEF6,COL9A1,BTF3L4,LETMD1,ACBD5,ZNF385A,ENTPD4,CS,SNCAIP,ARHGEF10,MICAL2,CSNK1E,OSBPL3,NCAN,PHF19,ZNF337,SPOCK2,AIF1L,ARMCX4,MYEF2,ELMO1,FBXL5,CEP170,GRIN3A,DNM1,DYRK1A,ABCC5,E2F6,AASDH,APH1A,EPHB1,DENND4A,CDHR1,MRPL10,SIRPB1,NRN1,ZNF461,TAOK3,KIAA1109,OLFM1,FGR,CAMSAP1,ANKFY1,TRMO,PDLIM5,NSG2,STAG2,GABRG2,ILDR2,DISC1,INPP5K,TUBA8,SRCAP,GLYR1,GNAS,LPAR4,GRIA4,RFFL,GRIK2,SERP2,KAT7,RNFT2,MAEL,TOX2,C1orf94,FRMD5,HMGB1,HSPA1L,IGSF1,LRRTM1,NME9,KCNC1,KCNJ10,KHK,KIF5A,KLRC3,MAT2A,NCAM1,NOS1,NPR2,DDR2,OMG,PAK3,PBX1,DPY19L2P2,CDK18,GDAP1L1,PIK3C2A,ST8SIA5,PURG,PMP22,SPATA6,MED1,RASGEF1B,RAB39A,HYDIN,PRPSAP2,GON4L,PTK2,PTPRG,PTPRO,FAM120C,RAB5B,SLC25A48,RAP1GDS1,ZNF493,FEZF2,HKR1,PRRT2,RGS3,RNASE1,RIC8B,RPRD1A,C12orf49,ACER3,RTKN,RYR3,NCBP3,SARS,ATXN2,LRRTM4,CASC3,COPZ1,ITSN1,FERMT1,SEC31A,ZNF365,EPN2,WDR47,LRRC55,SLC6A9,SIRT2,CCDC88A,ATF7IP,KIF21B,SP2,NFASC,ZNF302,SS18,ROBO3,EHBP1,ZFP90,PCDHB9,TNS2,CYB561A3,AP4E1,AKTIP,TNR,TPM3,KCNE5,SSBP2,FAM155A,DNAJC12,BCL2L13,WIPF1,NSD2,ZIC2,ZNF177,MEIS3,STOX2,RNF103,RGS7BP,GJC2,RNF170,PRRT4" MicroRNA hsa-miR-193b*:mirSVR_highEffct hsa-miR-193b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.35E-69 4.13E-65 3.00E-68 2.77E-67 189 837 "ASIC2,ABHD6,DSCAML1,SORCS1,FZD9,RNF150,BEND6,CC2D2A,FAM135A,KCNT1,MYH7B,DGKZ,UPRT,CACHD1,INSYN2B,NOL4,SGCE,CACNA1B,CAMK2G,VSTM2A,LDB2,CERS5,DGKI,SRSF11,CHN1,CASC2,JAM2,SLC22A6,CPNE6,NRXN3,PLAA,MYL6B,MAP4K4,CNGA3,COL9A1,SLC4A7,GAL3ST1,SMARCAL1,ZFP28,SLC35F1,SEC31B,CLOCK,C1QL2,GDA,CS,CSF1,CSF2RA,APPL1,UBXN2A,CTH,DCAF4,RUBCN,EDRF1,ARHGAP32,TOMM20,AIF1L,ARMCX4,CNIH3,SNAP91,SV2B,DLX1,DMD,DMPK,DNM1L,GOLT1B,EDNRA,PHF20L1,SUGP2,ELAVL4,EIF1,EMX2,RABEPK,IGSF6,ETV1,F5,SLC9B2,FGF1,FGFR1,FHL1,MEX3B,TMEM107,ERGIC3,ST6GALNAC3,STAU2,GABRA1,FAM184B,B4GALNT1,GAP43,ARFIP1,PCDH17,CRCP,GLYR1,TNRC6A,MSL3,GLUL,PCDH11X,GPD1,PCLO,GRIK5,IRAK3,ELOVL5,HMGCL,ZNF491,ZDHHC15,SMAP1,EID2B,RBPJ,IL6R,LRRTM1,KCNJ10,KIF5C,SMAD9,MAP6,MMP16,MOG,MSRA,CTNNA3,IDNK,VWA2,NTRK3,PCSK1,PCSK2,TMEM38A,PMP22,SH3KBP1,NKAIN4,MAPK3,GDPD1,SNRK,PSMD13,PTAFR,PTPRD,ZNF793,BSDC1,ZMAT4,RNASEL,CARF,YY1AP1,ACER3,ATAT1,YJEFN3,CLIP1,TRAPPC13,FAM192A,TNFRSF19,SHC4,MAGI3,FHOD3,FAM81A,DHX30,SEPHS1,CCDC88A,SLC14A1,UNC80,PDZD2,PEG10,ZC3H13,TSPYL2,SEPT8,SULF2,SEPT3,NECAB1,SYN1,SYNE1,RALYL,PCDHB9,SLC19A3,TNS2,CCDC173,ATP13A2,ZMAT3,ARL10,TIAM1,TIMP4,TNFRSF1B,CSMD1,SEZ6L,IL34,TRH,ZMYND8,PLEKHH2,BCL2L13,NSD2,RICTOR,ZIC1,NDRG4,ZNF138,SIGLEC10,RNF170" MicroRNA hsa-miR-549:mirSVR_highEffct hsa-miR-549:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.37E-69 4.14E-65 3.01E-68 2.77E-67 191 854 "SDE2,ABAT,KCNH8,CLK4,GPRIN1,SLC25A25,NDRG2,TMEM132B,ADD3,BEND6,KCTD16,AK2,PCDH10,AMPH,OGT,PPFIA2,APAF1,DGKD,BCAS1,MIER1,ARHGAP5,ZBTB10,ATP1A2,DPY19L3,BACH1,SYT6,KRIT1,LRBA,SOCS6,COG1,ARMC8,AKAP6,SMARCAL1,CLOCK,NCOR1,GDA,DZIP3,ERC2,CFAP61,PUM1,RUBCN,CCDC144A,CYBB,DAPK1,GIT2,ZEB2,HP1BP3,COPS7A,DDX46,ALKBH8,CHRDL1,EXOG,HS3ST4,DMTF1,PDCD6IP,SEMA3D,MBNL2,GOLGA7,TENM1,KCNMB2,RASL12,EFEMP1,CAMSAP1,FHL1,FOXG1,FLT1,NPTN,NSG2,AP4B1,SDCBP2,ZMAT1,ZNF44,GAD2,ARPP21,GAP43,ERAP1,C15orf41,ATP8A2,WASF3,BRD8,GLS,LUZP2,GPT2,LNX1,ADGRA3,PRUNE2,GRM7,LINC00839,MFSD2A,SOX21,RASSF8,MIER3,HMGB1,FAAP20,EID2B,ZNF546,ITGAV,KCND2,KCNMA1,CREG2,MAOB,MAP6,MARK1,AFDN,WDR49,CNOT4,NUCB2,OLR1,SNTG1,PAX6,PCDH9,PCSK2,SLC10A4,PFKFB2,CDK14,HMGCLL1,ING3,EPB41L4B,PPM1B,PRKCB,SNRK,CNTLN,PTPRD,RAB3A,ZNF493,ARID4A,ERI2,RPRD1A,GSTCD,ELP2,GLDN,WLS,FNIP1,SLC30A10,ASRGL1,SCAF8,SGK1,FERMT1,CPEB3,MAGI3,CHD9,FBXO11,SLC8A3,ZKSCAN3,ZFP1,ZNF667,LIMCH1,KIF13A,DOP1A,KIF21B,SP4,PEG10,SRPK2,SAMSN1,SMOC1,NEK4,TTBK2,KLHL7,VPS13A,SYN2,ATP11A,DDHD2,TAF9,ADGRL3,FBXL16,THRA,ZFP91,ERCC6L2,TMPO,NPL,NUTM2A,CLHC1,UBE3A,GUSBP1,TRIM9,AGMO,FSTL5,ZNF189,LAMP5,SMARCAD1,SYNC,EMSY,PRDM10,MDH1B,WNK3,RGS7BP,FAM13C,UBE3B,HNRNPA3,CASC15,SLC39A12" MicroRNA "TTGCACT,MIR-130A:MSigDB" "TTGCACT,MIR-130A:MSigDB" MSigDB 7.52E-69 4.23E-65 3.06E-68 2.82E-67 127 374 "ADCY2,HECW2,PITPNM2,OGT,LRCH2,PHF12,MIER1,NCOA1,ATP2B2,NRP2,NIPA1,LDLRAD4,CANX,USP6,SOCS6,ZFYVE9,PLAA,TPP1,CLTC,QKI,AKAP7,BTF3L4,ACBD5,CLOCK,CREB5,GDA,CSF1,LRIG1,SOCS5,PPP6R2,ST18,SNPH,LONRF1,MAML1,SPATA2,CEP170,G3BP2,WDR20,DNM2,DPYSL2,ABCC5,GOLT1B,ST8SIA3,KMT5B,PAN3,EMX2,ERBB4,ACSL4,TESK2,MED12L,FOXF2,NBEA,GAP43,ARFIP1,RAB30,TNRC6A,RAPGEF4,GRM7,RNF165,SOX21,BACH2,AGFG1,KIT,ARHGAP12,MAP4,MBNL1,MYT1,NEUROD1,CNOT4,NPTX1,PDGFRA,PFKFB3,POU3F2,PSD,MDGA2,PTPRG,RAB5B,ATG16L1,RBBP8,ROBO1,ROBO2,PRR5L,RTN1,RXRA,ATXN1,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,SHANK2,BTBD7,CPEB4,SNAP25,USP33,SOX5,CDK19,TSPYL2,SPART,SMOC1,ERBIN,DIP2A,GSE1,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMTA1,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,PMEPA1,MAP3K12,LRP8,SNX27,WNK3" MicroRNA "TTGCACT,MIR-301:MSigDB" "TTGCACT,MIR-301:MSigDB" MSigDB 7.52E-69 4.23E-65 3.06E-68 2.82E-67 127 374 "ADCY2,HECW2,PITPNM2,OGT,LRCH2,PHF12,MIER1,NCOA1,ATP2B2,NRP2,NIPA1,LDLRAD4,CANX,USP6,SOCS6,ZFYVE9,PLAA,TPP1,CLTC,QKI,AKAP7,BTF3L4,ACBD5,CLOCK,CREB5,GDA,CSF1,LRIG1,SOCS5,PPP6R2,ST18,SNPH,LONRF1,MAML1,SPATA2,CEP170,G3BP2,WDR20,DNM2,DPYSL2,ABCC5,GOLT1B,ST8SIA3,KMT5B,PAN3,EMX2,ERBB4,ACSL4,TESK2,MED12L,FOXF2,NBEA,GAP43,ARFIP1,RAB30,TNRC6A,RAPGEF4,GRM7,RNF165,SOX21,BACH2,AGFG1,KIT,ARHGAP12,MAP4,MBNL1,MYT1,NEUROD1,CNOT4,NPTX1,PDGFRA,PFKFB3,POU3F2,PSD,MDGA2,PTPRG,RAB5B,ATG16L1,RBBP8,ROBO1,ROBO2,PRR5L,RTN1,RXRA,ATXN1,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,SHANK2,BTBD7,CPEB4,SNAP25,USP33,SOX5,CDK19,TSPYL2,SPART,SMOC1,ERBIN,DIP2A,GSE1,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMTA1,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,PMEPA1,MAP3K12,LRP8,SNX27,WNK3" MicroRNA "TTGCACT,MIR-130B:MSigDB" "TTGCACT,MIR-130B:MSigDB" MSigDB 7.52E-69 4.23E-65 3.06E-68 2.82E-67 127 374 "ADCY2,HECW2,PITPNM2,OGT,LRCH2,PHF12,MIER1,NCOA1,ATP2B2,NRP2,NIPA1,LDLRAD4,CANX,USP6,SOCS6,ZFYVE9,PLAA,TPP1,CLTC,QKI,AKAP7,BTF3L4,ACBD5,CLOCK,CREB5,GDA,CSF1,LRIG1,SOCS5,PPP6R2,ST18,SNPH,LONRF1,MAML1,SPATA2,CEP170,G3BP2,WDR20,DNM2,DPYSL2,ABCC5,GOLT1B,ST8SIA3,KMT5B,PAN3,EMX2,ERBB4,ACSL4,TESK2,MED12L,FOXF2,NBEA,GAP43,ARFIP1,RAB30,TNRC6A,RAPGEF4,GRM7,RNF165,SOX21,BACH2,AGFG1,KIT,ARHGAP12,MAP4,MBNL1,MYT1,NEUROD1,CNOT4,NPTX1,PDGFRA,PFKFB3,POU3F2,PSD,MDGA2,PTPRG,RAB5B,ATG16L1,RBBP8,ROBO1,ROBO2,PRR5L,RTN1,RXRA,ATXN1,PUF60,CHD9,SYBU,BTBD3,WDR47,CCDC88A,SHANK2,BTBD7,CPEB4,SNAP25,USP33,SOX5,CDK19,TSPYL2,SPART,SMOC1,ERBIN,DIP2A,GSE1,PLCB1,ANKRD28,ATP11A,ANKRD12,CAMTA1,TRIM2,ARHGEF12,DICER1,ZFPM2,SLC44A1,ZFP91,R3HDM1,CSMD1,TRPS1,TSC1,USP32P2,SPHK2,FSTL5,PMEPA1,MAP3K12,LRP8,SNX27,WNK3" MicroRNA hsa-miR-562:mirSVR_highEffct hsa-miR-562:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.81E-69 4.39E-65 3.18E-68 2.93E-67 183 787 "ACADM,NCKAP5,ADD3,ZNF608,GPR158,KCTD16,KIAA1324,SEMA7A,PPFIA1,ASPH,ZBTB10,ATM,ATP2A2,N4BP2L1,NOL4,DPY19L3,ATP6V1G2,ARHGEF7,C5,IL33,CACNB4,PRC1,CFL2,SRSF11,CHM,CHN1,JAM2,NRXN1,DNAJB5,HECTD1,NIPBL,SLC4A8,RNF14,FEZ2,CTH,CFAP61,ARHGAP24,MATR3,MAGI2,DDX46,PLPPR4,DNM1L,ABCC9,EDNRB,KMT5B,ASB3,EIF4G2,CALCRL,KCNMB2,GPHN,SRRM1,F8,WAC,CEP78,GORAB,SLC9B2,FER,FGFR1,POLK,MEX3B,SYNCRIP,HVCN1,UFM1,ATP6V1H,ST6GALNAC3,NSG1,ABLIM2,ZMAT1,TRAF3IP2,USP19,GHR,PPARGC1A,BRD8,INSM2,KCNMB4,GOLGB1,RAPGEF4,GRIA4,CIT,PSIP1,GUCY1B1,MAEL,C1orf94,OPALIN,BTBD17,IDH3B,RBPJ,RIPPLY2,ITGAM,KIF5C,LAMP2,LIG4,FGFBP3,C2orf80,MAG,MEF2C,MEIS1,ZNF92,NAP1L1,P2RY13,PAK3,PCSK2,BEST3,HMGCLL1,LRP12,PSAT1,PMS2,PRRX1,EPB41L4B,TATDN3,PPP2R5C,PPP2R5E,PROX1,RELN,SNRK,PIGG,PTPN13,PTPRB,PTPRD,PTPRG,TTC13,RAD17,RASGRF2,FIGN,SETD5,RPE,UEVLD,BAALC,LRRK2,ABCA11P,DGLUCY,SCP2,SH3BGR,SH3GL2,PPM1E,RUFY2,KANSL3,SLC12A2,SLC14A1,INTS9,IFT122,ANKRD36,RIMS1,TMCC1,MYO16,TRERF1,SOX5,KIF21B,ZC3H13,ZBTB43,SPART,PBLD,CLASP2,SEPT3,NECAB1,VAMP1,FNDC9,TACR1,PJA1,TAF9,TBCEL,PCDHB10,PCDHB4,PMS2CL,SIRT1,TPM1,TRPC1,CADM1,RPRM,UBE3A,UCHL1,ZBTB14,ZNF711,TRIM9,PLPP4,SYNC,EMSY,PRDM8,PCDH15,WNK3,SLC17A6,FAM13C,SMIM8" MicroRNA hsa-miR-3172:mirSVR_highEffct hsa-miR-3172:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.03E-69 5.07E-65 3.67E-68 3.38E-67 189 838 "ASIC2,ABHD6,ADCY2,DSCAML1,SORCS1,FZD9,RNF150,OSBPL1A,CC2D2A,FAM135A,KCNT1,MYH7B,DGKZ,UPRT,CACHD1,INSYN2B,NOL4,SGCE,CACNA1B,CAMK2G,VSTM2A,LDB2,CERS5,SRSF11,CHN1,CASC2,JAM2,SLC22A6,CPNE6,NRXN3,PLAA,MYL6B,MAP4K4,CNGA3,COL9A1,SLC4A7,GAL3ST1,SMARCAL1,ZFP28,SLC35F1,SEC31B,CLOCK,C1QL2,GDA,CS,CSF1,CSF2RA,APPL1,UBXN2A,CTH,DCAF4,RUBCN,EDRF1,ARHGAP32,TOMM20,AIF1L,ARMCX4,CNIH3,SNAP91,SV2B,DLX1,DMD,DNM1L,GOLT1B,EDNRA,PHF20L1,SUGP2,ELAVL4,EIF1,EMX2,RABEPK,IGSF6,ETV1,F5,FGF1,FGFR1,FHL1,MEX3B,TMEM107,ERGIC3,STAU2,GABRA1,FAM184B,B4GALNT1,GAP43,ARFIP1,PCDH17,CRCP,GLYR1,TNRC6A,MSL3,GLUL,PCDH11X,GPD1,PCLO,GRIK5,ATOH8,IRAK3,ELOVL5,HMGCL,ZNF491,ZDHHC15,SMAP1,EID2B,RBPJ,IL6R,LRRTM1,KCNJ10,KIF5C,SMAD9,MAP6,MOG,MSRA,CTNNA3,IDNK,VWA2,NTRK3,PCSK1,PCSK2,TMEM38A,PMP22,SH3KBP1,NKAIN4,MAPK3,GDPD1,SNRK,PSMD13,PTAFR,PTPRD,ZNF793,BSDC1,ZMAT4,RNASEL,CARF,YY1AP1,ACER3,ATAT1,YJEFN3,CLIP1,TRAPPC13,FAM192A,SEMA6D,TNFRSF19,SHC4,MAGI3,CHD9,FHOD3,FAM81A,DHX30,SEPHS1,CCDC88A,SLC14A1,UNC80,PDZD2,KDM4C,ZC3H13,TSPYL2,SEPT8,SULF2,SEPT3,NECAB1,SYN1,TCF4,SZT2,SYNE1,RALYL,PCDHB9,SLC19A3,TNS2,CCDC173,ATP13A2,ZMAT3,ARL10,TIMP4,TNFRSF1B,CSMD1,SEZ6L,TRH,ZMYND8,PLEKHH2,BCL2L13,VGF,NSD2,RICTOR,ZIC1,NDRG4,ZNF138,SIGLEC10,RNF170" MicroRNA hsa-miR-553:mirSVR_lowEffct hsa-miR-553:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-68 7.02E-65 5.08E-68 4.68E-67 163 629 "RALGAPA1,NCKAP5,ADCY2,ADD3,USP31,PWWP2A,TBC1D14,WDR35,SPOP,CEP126,ZNF687,PHF12,GPAM,CACHD1,LRRC4C,ARHGAP5,NUMB,ATP2B1,ADGRB1,BCHE,ARHGEF7,OSGIN2,CALB1,MAP7,CLDN10,TIGD7,B4GALT6,JAM2,LHX2,EPS15L1,CLCN4,TPP1,FAM19A5,NIPBL,CNN3,ARMC8,SNCAIP,EDRF1,HDAC4,PLPPR4,SPOCK3,NTM,GNE,DNAJB6,ABCC5,EDNRB,HIPK3,SH3GLB1,FAM13A,EGFR,MBNL2,COPS4,PLEKHA1,ZNF549,SPEG,CDKL3,ETV1,TAOK3,SPSB4,CAP2,FLT1,TMEM107,ARFGAP2,PNMA2,NEURL4,DISC1,GCNT2,AHDC1,GGT7,RNPS1,FERMT2,DIDO1,GRIA4,GRM7,CLASRP,PSIP1,GYG1,WIF1,TOX2,SHISA6,LINC00667,DOCK7,USP54,INSM1,ZNF385B,KCND1,STXBP5,KTN1,MAN2A2,MBP,SESN3,ADAM22,MYO9A,NEUROD1,NF1,LRIT2,NTRK2,PLIN1,MAPKAP1,STRN3,PPP3CA,NDUFS7,WBP1L,SNRK,TUG1,RASGRF1,ZDHHC4,DCUN1D2,ROBO2,CCDC25,CCDC102B,RPE65,LRRK2,HSD11B1L,KCNIP3,LRRTM4,FAM19A1,SCAF8,FERMT1,DOCK10,SYBU,PREX2,SHANK2,TMEM132D,ZFP1,DMRTC1,SNRPN,TMCC1,WDTC1,BDP1,SPART,CLASP2,CEP68,DIP2A,KANK1,FGD4,SYN2,ANKRD12,DDHD2,FAM208A,FBXW11,TCF7L2,RALYL,ARHGEF12,SIRT1,ITGB3BP,TJP1,TMOD1,TPD52,RGMB,PRMT8,PPIL6,PLEKHH2,MGAT5B,VAV2,RBFOX3,ZNF781,ZBTB14,NDRG4,ANKS1B,EMSY,GAL3ST3,PHTF2" MicroRNA hsa-miR-129-2-3p:TargetScan hsa-miR-129-2-3p TargetScan 1.46E-68 8.21E-65 5.93E-68 5.46E-67 124 357 "FMNL2,ADD2,GRAMD1B,KLHL13,CASKIN1,NCOA1,BCL2L2,BCL7A,FUBP1,CACNA1I,MYRF,CACNA1B,CACNA1D,CACNA1E,CACNB4,MAP7,CCNT1,DGKI,DLGAP2,NUMBL,RCBTB2,DNAJB5,HECTD1,AKAP5,RCHY1,FAM171B,SEC24C,PLXNA4,PLCXD3,CCDC144A,RIMS3,IP6K1,CTIF,AIF1L,DCC,ELMSAN1,MYEF2,RHOBTB1,SACS,DLG2,CALN1,E2F5,FAM135B,PLXNC1,ELAVL3,RGS17,RCAN2,CEP85L,AKAP3,NBEA,NPTN,ARFGAP2,CAMKK2,FUT9,MSANTD4,GABRA1,GABRG1,ILDR2,AHCYL1,JPH4,NCKAP1,GPR75,GPM6B,CACFD1,GRIN2D,NR3C1,PRDM5,PTPRT,GUCY1A2,FRMD3,KLF12,IGFBPL1,DIPK1A,KCNB1,LIFR,PAXBP1,MAPT,MMP16,NEK1,NFIA,GPR137C,PAK3,FTO,MED1,PKIA,MAPK3,MAPK10,ELOVL2,RAB5B,RASGRF2,GTDC1,ROBO1,BAALC,RYR3,AMER2,SEC14L1,ABLIM3,BTBD7,RIMS1,SCN3B,NMNAT2,GSE1,ANKRD12,CAMSAP2,CNTN2,CLASP1,NSD1,GPRIN3,FRYL,NACC2,HEY1,FAM124A,FNDC5,FAM155A,FLRT2,RBFOX3,RICTOR,REEP1,HPS4,NAV3,NAV2,MVB12B,PHTF2,FBXO36" MicroRNA hsa-miR-129-1-3p:TargetScan hsa-miR-129-1-3p TargetScan 1.46E-68 8.21E-65 5.93E-68 5.46E-67 124 357 "FMNL2,ADD2,GRAMD1B,KLHL13,CASKIN1,NCOA1,BCL2L2,BCL7A,FUBP1,CACNA1I,MYRF,CACNA1B,CACNA1D,CACNA1E,CACNB4,MAP7,CCNT1,DGKI,DLGAP2,NUMBL,RCBTB2,DNAJB5,HECTD1,AKAP5,RCHY1,FAM171B,SEC24C,PLXNA4,PLCXD3,CCDC144A,RIMS3,IP6K1,CTIF,AIF1L,DCC,ELMSAN1,MYEF2,RHOBTB1,SACS,DLG2,CALN1,E2F5,FAM135B,PLXNC1,ELAVL3,RGS17,RCAN2,CEP85L,AKAP3,NBEA,NPTN,ARFGAP2,CAMKK2,FUT9,MSANTD4,GABRA1,GABRG1,ILDR2,AHCYL1,JPH4,NCKAP1,GPR75,GPM6B,CACFD1,GRIN2D,NR3C1,PRDM5,PTPRT,GUCY1A2,FRMD3,KLF12,IGFBPL1,DIPK1A,KCNB1,LIFR,PAXBP1,MAPT,MMP16,NEK1,NFIA,GPR137C,PAK3,FTO,MED1,PKIA,MAPK3,MAPK10,ELOVL2,RAB5B,RASGRF2,GTDC1,ROBO1,BAALC,RYR3,AMER2,SEC14L1,ABLIM3,BTBD7,RIMS1,SCN3B,NMNAT2,GSE1,ANKRD12,CAMSAP2,CNTN2,CLASP1,NSD1,GPRIN3,FRYL,NACC2,HEY1,FAM124A,FNDC5,FAM155A,FLRT2,RBFOX3,RICTOR,REEP1,HPS4,NAV3,NAV2,MVB12B,PHTF2,FBXO36" MicroRNA hsa-miR-3190-3p:mirSVR_highEffct hsa-miR-3190-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-68 9.40E-65 6.78E-68 6.25E-67 189 841 "RALGAPA1,KLHL32,ADD1,ADD2,MTUS1,KIAA1324,C1QTNF3,OGT,DPP10,PHF12,SUGT1P4-STRA6LP-CCDC180,VAT1L,USP37,ARSF,DACT3,NUMB,ASTN1,INSYN2B,TMEM108,ATM,ATP1B3,ZNF583,N4BP2L1,DPY19L3,ARHGEF7,CACNB2,CALM1,METTL6,LRBA,CDC42,ZMYM4,LGI1,SRSF11,TPP1,TMEM59L,TJP2,ARMC8,ABI3BP,ZFP28,CPS1,FAM171B,CSF1,TENM4,FEZ1,SOCS5,BOC,DOCK4,DAPK1,AIF1L,PITPNC1,FAM107B,CHRDL1,DLG2,DTNB,E2F6,FAM135B,PHC2,FRY,ELAVL4,EPB41,RABEPK,IGSF6,RTN3,FCGR1A,FDFT1,GORAB,POLR1B,SUCO,SGIP1,UFM1,STAMBP,ERGIC3,NSG1,MEGF11,GABRA1,NEK6,GJB1,GK,TNRC6A,PCDH11X,KDM2B,PSRC1,PRUNE2,GPM6B,GPER1,PCLO,GRIA4,GRM1,KAT7,WIF1,NCKAP1L,HPCA,SHISA6,SMAP1,IL6ST,INPP1,KCND1,KIF5A,KIT,LRRC4B,PAXBP1,SYTL4,MAOB,MATN2,MBD1,SYT9,MOBP,BLOC1S2,NAP1L3,ZC3H12B,NEUROD2,NF1,DNHD1,NPR2,P2RX7,ZNF827,PAH,PDGFRA,BEST3,PFKFB2,ZNF655,PKM,ST8SIA5,SMIM7,PURG,C11orf49,PMP22,PILRA,TMEM235,PRKCG,PKN2,GDPD2,PSMD13,PTHLH,RAB5B,ATG16L1,RASGRF2,TRIM68,RNASEL,ZNF532,EXD2,CARF,MRAP2,ARMH4,MCMBP,TCP11L1,KCNIP1,LRRTM4,PEAR1,TRIM46,CASC3,COPZ1,FNDC3A,ZNF365,SLC6A1,EFHD1,SMARCE1,TTC17,MYT1L,TNIK,VPS13A,DDHD2,ROBO3,CAMSAP2,DMXL2,CUX2,USP32P1,TIAM1,C9orf85,TRPC3,ZMYND8,TMEFF2,BEST1,NSD2,XPO1,PLPP4,LYPD6,CSDE1,STOX2,LMAN2L,WNK3,GOPC,AMN1,FZD3,MARCH8,RTN4,PHTF2,KLHDC1,PRRT4" MicroRNA hsa-miR-20a-5p:Functional MTI Functional MTI miRTarbase 1.74E-68 9.78E-65 7.05E-68 6.50E-67 215 1071 "RBM10,ADAR,FMNL2,ADD1,FZD9,SORCS2,ZNF578,KIF6,SEMA7A,USP28,GPAM,APP,CAPRIN2,ATP1B3,ATP2B1,MTMR9,BACH1,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,FOXK1,MAP7,FMNL3,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,SLC4A7,ACBD5,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,NCOR2,FEZ2,SOCS5,UBXN2A,DCAF8,KIAA0513,TOMM20,DAPK3,SIRPA,DNAL1,YTHDC1,ELMSAN1,PLEKHM1,FBXL5,CEP170,SACS,RABGAP1L,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,ETV1,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,DLC1,GTF2IRD2,POLR1B,SUCO,ANKFY1,USP16,TPK1,SARAF,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,GNAS,FUT10,NUDT21,RAPGEF4,NR3C1,CIT,MFSD2A,FICD,HAS2,HMGB1,ITPKB,JAK1,KCNB1,KCND3,KIT,CAMK2N2,ARHGAP12,GPR155,CHIC1,SCAMP5,AFF1,SESN3,MXI1,NAP1L1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,PFKP,CCSER2,PKD1,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,SLC22A23,PXK,OCIAD1,PTPRO,RAB5B,CEP97,ATG16L1,OXR1,RPRD1A,ZNF532,TMEM100,UEVLD,ATAT1,ZNF331,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,RUFY2,KDM4D,BTBD7,CMTR2,FAM126B,SON,SP2,SP4,EMC1,CDK19,POGZ,SMOC1,STAC2,PRRC2C,ANKRD12,CAMTA1,ADGRL3,WWC1,TCEA1,TCF4,TCF7L2,PSD3,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,DDHD1,PARD3,TPM4,RGMB,NR2C2,UBC,TBC1D15,NSD2,ZNF70,LYPD6,INTS3,MAP3K12,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,NUP214,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-3166:mirSVR_highEffct hsa-miR-3166:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.83E-68 1.03E-64 7.40E-68 6.82E-67 198 919 "CLK4,CSMD2,DPY19L2P4,AP2A2,INTS2,KCTD16,ZNF578,ALCAM,OGT,APBB1,ALS2,VAT1L,API5,SHTN1,MIER1,MARCH3,NCOA1,ATP2B2,B3GALT2,CADM3,RGS9,ARHGEF7,BAIAP3,CACNA1B,KALRN,CANX,CCKBR,CDH10,ZMYM4,TIGD7,MS4A7,TPP1,SULT4A1,AKAP7,COL9A1,LETMD1,SLC4A8,ACBD5,HS3ST5,FAM171B,PREPL,RNF14,SNCAIP,CSF2RA,SEC24C,OSBPL3,ATRNL1,ERC2,UBXN2A,GAPVD1,C8orf34,ZEB2,G3BP2,ZNF582-AS1,DLG3,USP3,TRAPPC9,CPEB2,DSCAM,DTNA,ATL1,ANKRD46,CELSR3,EGR3,GOLGA7,EN2,GPHN,CEP85L,ADGRV1,EYA1,WAC,FABP7,FCGRT,KIAA1109,FHL1,SUCO,SYNCRIP,NOP56,ATP2C1,NSG1,GABBR1,AHCYL1,FAM120B,RAPGEF6,ARPP21,DISC1,SPIN1,RAB30,GLS,DCLK2,FERMT2,PCLO,STMN2,GRM2,RABL2A,MAEL,HMGCR,DOCK7,IGSF1,MEIS1,NPR2,IGSF11,CLDN11,GPR137C,PDE4B,NALCN,FAM218A,XRN1,HMGCLL1,PPP2R5C,PRKCZ,SIDT1,MDGA2,BDNF-AS,PTHLH,TMEM260,MARCH1,CEP97,RAP1GDS1,OXR1,SLC6A15,ZYG11B,FIGN,RFX4,RGS7,MRPS18A,SEC61A2,NUDT11,PNMA8A,GSTCD,KIRREL1,RORB,RPL15,CNTNAP3,MEG3,SEMA6D,SATB1,SMPD3,COPZ1,SCAF8,KIF21A,CPEB3,NTNG1,SHC4,WDR37,ZNF365,WDR47,SLC8A3,KBTBD4,CPEB4,SORCS3,INTS9,MYT1L,TNIK,UHRF1BP1L,KDM4C,ZNF423,KIF1B,RBM26,ERBIN,POPDC3,CAMTA1,UNC5D,ZEB1,WASHC4,WDR7,PCDHB9,FRYL,RNF216P1,CRB1,HHIP,SLC44A1,GZF1,MTMR14,HEY1,KAT6B,PIK3R5,RGMB,TRPC3,SSBP2,TTC3,PITPNB,PCDH20,ZNF19,TCEAL7,ZBTB16,FSTL5,CA10,EMSY,LINC02210,WIPF2,WNK3,RGS7BP,FZD3,CAMK1G,TIGD6,FRMD6,RNF146" MicroRNA hsa-miR-934:mirSVR_highEffct hsa-miR-934:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.14E-68 1.20E-64 8.67E-68 7.98E-67 156 578 "KCNH8,NDRG3,SORCS1,RNF150,DPY19L2P4,RTL9,CC2D2A,CDC42BPA,VAT1L,BCAS1,STK33,ASPH,ATP2A2,N4BP2L1,BBS2,NRP2,SYNJ2,CAST,RUNX1T1,METTL6,SLC16A4,MAGI1,KMT2C,PLAA,COG1,NIPBL,SLC25A27,SLC4A7,BAG4,TOGARAM2,SLC35F1,SEC31B,PREPL,GDA,CLIP3,SNCAIP,CSNK1E,VCAN,NCAN,RUBCN,GIT2,YTHDC1,CEP170,DLG3,GRIN3A,USP3,GNE,EFNA3,APH1A,SORBS3,EIF5,EML1,DCTN4,EPB41L1,LRRC17,EPHB1,GPHN,WAC,ACSL4,KIAA1109,SYNCRIP,UFM1,ZNF605,AP4B1,GABRA2,KIAA1841,GHR,MSL3,ZNF638,DCLK2,PRLHR,FAM19A2,PSIP1,MIER3,SYNPO,SOWAHA,LRRCC1,KCND2,KCNJ10,KCNMA1,KHK,INSYN2,PAXBP1,NCOA7,MBP,SCG3,MXI1,MYCN,NF1,NOVA1,PDE4D,PDGFRA,GDAP1L1,ZNF655,PURG,SPATA6,DRAM2,MINDY2,LRRN3,CRLS1,KANSL1,RAB39A,PRPSAP2,GON4L,PSMD13,CNTLN,ELOVL2,TMEM260,PPP2R3C,OXR1,DBX2,KHDRBS2,MSANTD2,ERI2,ZDHHC4,SEC61A2,SETD5,ACER3,TMEM156,LINC00461,SLC30A10,SH3BGR,ITSN1,ZNF365,BTBD3,SPHKAP,TET1,RCOR3,ZCCHC24,C11orf87,ANKRD28,SLC37A2,SYT4,MTCL1,TAL1,TRIM2,SYNE1,PUM2,THRA,ACTR6,SYNPO2,PRMT8,DCBLD1,SSBP2,RFTN2,TTC3,USP1,RICTOR,ZBTB14,TCEAL7,SYNC,ADAMTS9,FIP1L1,WNK3,PLSCR4,JMJD1C" MicroRNA hsa-miR-1912:mirSVR_highEffct hsa-miR-1912:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.43E-68 1.37E-64 9.83E-68 9.05E-67 178 751 "ASIC2,ARID1A,XKR4,NDRG3,FMNL2,GALNT16,SLITRK1,ADD3,KCTD16,OSBPL6,TXNDC16,DPP10,CNIH2,DDO,BCAS1,LGR5,ADAM23,ST3GAL5,KALRN,CAST,NFS1,CBLN1,AIFM1,SEPT7,CDH8,B4GALT6,NRXN3,PLAA,IQCK,ABI3BP,IFFO1,COX4I1,MFSD4A,RBM39,RNF14,ST18,EDRF1,FGFR1OP2,TOMM20,SIRPA,DCC,LYPD1,GSDME,SMG7,NTM,EXOG,DMD,DNAH9,DYNC1I1,CPEB2,DMTF1,DTNB,GOLT1B,SYT15,PHF20L1,KMT5B,EIF1,OLIG2,EPB41L1,EPHB1,F5,ABCA8,RACK1,ZSCAN30,FDFT1,ACTL6B,ATP13A4,USP16,ATP2C1,MEGF10,ZMYND11,WASF3,TCERG1,SPIN1,KCNMB4,ADGRA3,GRIK2,LINC01551,HRH3,GABARAPL2,TCEAL6,EID2B,NKD1,KCNN3,NCOA7,MATN2,MEF2C,MEIS1,MOBP,OCRL,OGG1,PCSK1,PCSK5,PDCD2,NLGN3,A2ML1,PLIN1,CDIP1,SCHIP1,MED1,PPM1B,LRRN3,PPP3CB,APTX,SIDT1,GON4L,SNRK,PSMD13,SPDL1,PTPRG,USP47,ENOX1,SLC6A15,RET,FIGN,MRPS18A,SLC25A36,SETD5,GSTCD,RPL15,PRR5L,ACER3,TCP11L1,LRRTM4,SCN8A,PRCD,PEAR1,ITSN1,HKDC1,FHOD3,R3HDM2,SYBU,KANSL3,PKNOX2,SLC12A2,EFHD1,TET1,KIF13A,CMTR2,SON,SOX1,SOX5,UHRF1BP1L,KDM4C,NPAS3,SRPK2,TAB2,CLSTN2,GANAB,FNDC9,PLCB1,CAMSAP2,VWA3A,SATB2,ZEB1,RPGRIP1L,SYNE1,PCDHB7,ITGB3BP,ARL10,TLL2,BHLHB9,ERCC6L2,SEZ6L,TPM3,TRIO,AMOT,WRN,CLDND1,ZBTB14,CSDE1,PRDM10,NAV3,CAB39L,GOPC,KAT6A,SLC4A10,JPH3" MicroRNA hsa-miR-548m:PITA hsa-miR-548m:PITA_TOP PITA 2.80E-68 1.57E-64 1.13E-67 1.04E-66 139 457 "DSCAML1,SLITRK1,PWWP2A,PTCHD1,BEND6,HECW2,FAM135A,OGT,DPP10,APAF1,EPB41L5,API5,SHTN1,AQP4,TMEM263,CDK13,NOL4,CANX,MAP7,SEPT7,CDH2,LGI1,MAGI1,CCPG1,SRSF11,FOXN3,B4GALT6,CLCN3,QKI,SLC4A7,SLC35F1,CREB5,HAPLN1,KIAA0408,DOCK4,FRMPD4,DNAJC6,ZEB2,MYEF2,CEP170,ALKBH8,CPEB2,DSCAM,FRY,RBM12,CELSR3,PAN3,KCNMB2,CEP78,FKTN,FGFR3,SUCO,UBE2E3,CAP2,PDLIM5,ARFIP1,PCDH17,TCERG1,RNPS1,SPIN1,KDM2B,GPM6A,ATF7,PCLO,GRM3,CIT,IL1RAPL1,ADAMTS6,HAS2,DDX19B,BACH2,TCEAL6,C5orf24,RBPJ,INSM1,KIF2A,KIF5C,STXBP5,MAP2,SYT9,MEIS2,MXI1,NEXMIF,PABPC1L2A,NEUROD1,NOVA1,PDE2A,MINDY2,PTPRD,SLC25A36,ZFHX4,ZNF532,RORB,ACER3,CLIP1,TNFRSF19,SOX6,SCAF8,PPM1E,CPEB3,MAGI3,EPN2,CCDC88A,TRIM67,SORCS3,RCOR3,PALLD,SON,RGL1,ADAMTS17,PLCB1,ANKRD28,CAMSAP2,AGTPBP1,ANO4,ARHGEF12,CRTC1,FRYL,DICER1,HHIP,SLC44A1,TJP1,KAT6B,TPM3,TRPC3,CADM1,VLDLR,WNK1,SNX27,KCNAB1,WNK3,PDSS2,MARCH8,PAK5,KAT6A,NETO2,SOCS4,ST8SIA2,JPH3" MicroRNA hsa-miR-132-3p:TargetScan hsa-miR-132-3p TargetScan 3.09E-68 1.74E-64 1.25E-67 1.15E-66 124 359 "ABR,C3orf14,ARID1A,ELFN2,KIAA1211,OSBPL8,PCDH10,CDC42BPA,BSN,PTBP2,HIP1R,RUNX1T1,CBFA2T2,CDH8,CFL2,GPR37L1,FOXN3,B4GALT6,NMT2,QKI,HECTD1,NRG2,CLOCK,CREB5,HAPLN1,NCOR1,DOCK4,ARHGAP32,GAPVD1,DCAF8,FRMPD4,DCC,ELMSAN1,SEC16A,DUSP9,E2F5,EDIL3,RASGRP1,RBM12,CELSR3,PHF20L1,PAN3,NCALD,ETV1,EXTL2,CACNG2,OLFM1,FOXO3,AFF2,ARFGAP2,DKK3,GAB1,SALL3,GHR,KIAA1958,GPD2,GRM3,KAT7,HAS2,LRRTM3,KCNA6,KCNK2,KCNN3,KIF2A,MSANTD3-TMEFF1,MAPT,MEIS1,MEIS2,KITLG,POC1B,MITF,MMP16,NFIA,NFYA,NOVA1,NRCAM,PDGFRA,PPP2R5C,PPP2R5E,PPP3CA,MAPK3,FITM2,PTCH1,MTMR10,PTPRD,KHDRBS2,RDX,PRRT2,GTDC1,RFX3,RORB,FBXW7,HUNK,SALL1,CSRNP3,ATXN1,ATXN7,SCN2A,SCN3A,ARX,NTNG1,RPH3A,CCDC88A,BTBD7,EPC1,MAPKBP1,KIF21B,NMNAT2,MYCBP2,CDK19,C11orf87,CLSTN2,CAMSAP2,SATB2,CRTC1,GPRIN3,HHIP,NACC2,AMOT,NDRG4,CSDE1,RGS7BP,KAT6A,FXR1" MicroRNA hsa-miR-212-3p:TargetScan hsa-miR-212-3p TargetScan 3.09E-68 1.74E-64 1.25E-67 1.15E-66 124 359 "ABR,C3orf14,ARID1A,ELFN2,KIAA1211,OSBPL8,PCDH10,CDC42BPA,BSN,PTBP2,HIP1R,RUNX1T1,CBFA2T2,CDH8,CFL2,GPR37L1,FOXN3,B4GALT6,NMT2,QKI,HECTD1,NRG2,CLOCK,CREB5,HAPLN1,NCOR1,DOCK4,ARHGAP32,GAPVD1,DCAF8,FRMPD4,DCC,ELMSAN1,SEC16A,DUSP9,E2F5,EDIL3,RASGRP1,RBM12,CELSR3,PHF20L1,PAN3,NCALD,ETV1,EXTL2,CACNG2,OLFM1,FOXO3,AFF2,ARFGAP2,DKK3,GAB1,SALL3,GHR,KIAA1958,GPD2,GRM3,KAT7,HAS2,LRRTM3,KCNA6,KCNK2,KCNN3,KIF2A,MSANTD3-TMEFF1,MAPT,MEIS1,MEIS2,KITLG,POC1B,MITF,MMP16,NFIA,NFYA,NOVA1,NRCAM,PDGFRA,PPP2R5C,PPP2R5E,PPP3CA,MAPK3,FITM2,PTCH1,MTMR10,PTPRD,KHDRBS2,RDX,PRRT2,GTDC1,RFX3,RORB,FBXW7,HUNK,SALL1,CSRNP3,ATXN1,ATXN7,SCN2A,SCN3A,ARX,NTNG1,RPH3A,CCDC88A,BTBD7,EPC1,MAPKBP1,KIF21B,NMNAT2,MYCBP2,CDK19,C11orf87,CLSTN2,CAMSAP2,SATB2,CRTC1,GPRIN3,HHIP,NACC2,AMOT,NDRG4,CSDE1,RGS7BP,KAT6A,FXR1" MicroRNA hsa-miR-921:mirSVR_highEffct hsa-miR-921:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.25E-68 2.39E-64 1.71E-67 1.58E-66 168 673 "NDRG2,TMCC3,ADD3,KIAA1211,ADRB2,KIDINS220,SLC44A5,RTL9,ADGRF5,C1QTNF3,ALCAM,FAM135A,OGT,EP400,MAP4K3,CNIH2,UPRT,MIER1,IGDCC4,ARHGDIA,ADAM23,ADGRB3,MPDZ,MTMR2,BTRC,CBR1,METTL6,RCBTB2,MS4A7,B4GALT6,KMT2C,TPP1,C4orf33,HECTD1,NIPBL,CNRIP1,LRRC3B,CST3,UBXN2A,PNPLA8,PUM1,ZSCAN23,MYADM,KIAA0586,DCC,COPS7A,SPOCK3,CHRDL1,DTNA,ABCC9,EDNRB,SGK2,SUGP2,MBNL2,ELAVL4,DCTN4,ADGRV1,EYA1,F8,GTF2IRD2,SEC23B,STAMBP,MSANTD4,ZMAT1,DKK3,GABRA2,DISC1,INPP5K,GART,GHR,LILRA1,NR3C1,GRM1,KAT7,ZBTB49,AP4S1,ADAMTS6,GUCY1B1,HAS2,ZHX1,MIER3,VSIG4,HSF2,SHISA6,MSL1,IDH3A,NKD1,USP54,IGSF1,ZNF678,SLC35G1,KCNN2,KCNN3,KIF5A,KLC1,LOC100128239,MARK1,MEIS2,KITLG,NDUFA5,NEK1,TBC1D25,GPR137C,PCSK5,ANLN,A2ML1,ZFYVE21,FAM216A,JAKMIP1,HMGCLL1,POU3F2,PPM1B,KANSL1,DIRAS2,BDNF-AS,TMEM260,PTPRB,EML5,ACSM5,QDPR,PID1,PCMTD2,NCBP3,KIF21A,SHC4,MAGI3,SLITRK3,SLC1A6,SLC6A8,SLC6A11,CCDC88A,BTBD7,SNCA,ZNF415,FAM219A,SON,KDM3A,SP4,ENKUR,KDM4C,CDK19,LMO3,CLASP2,TROVE2,NKAIN2,SEPT8,ADGRL3,DMXL2,TMPO,RBFOX2,TPM1,SYNPO2,STXBP4,TMPRSS5,RFTN2,CADM1,MTCH1,RICTOR,GUSBP1,ZNF711,AGMO,FSTL5,SMARCAD1,SYNC,PCDH15,TIGD6,RNF170,FAM198A" MicroRNA hsa-miR-140-3p.1:TargetScan hsa-miR-140-3p.1 TargetScan 5.52E-68 3.10E-64 2.22E-67 2.05E-66 142 480 "ADD3,PTCHD1,KCTD16,PCDH10,PPFIA2,ARHGAP5,ARRB1,CCDC74A,CAPRIN2,ATP2B1,NOL4,BSN,LDLRAD4,CACNA1E,CABP7,HAP1,CAMK2G,FMNL3,CCNT1,CDH8,LRRFIP1,NDST3,DLGAP3,KIAA1549L,CLTC,RCHY1,ACBD5,NSL1,CLOCK,LRIG1,NCAN,PLXNA4,CCDC144A,MATR3,ELMSAN1,PLEKHM1,ELMO1,HP1BP3,CEP170,G3BP2,ARNT2,GRIN3A,HS3ST2,CPEB2,DRP2,RCAN1,FAM78B,DYRK1A,DNM1L,RBM12,PLXNC1,ELAVL3,EZH1,FCGRT,FGF13,ANKFY1,CELF1,GABRB1,BRPF3,NCKAP1,GHR,GK,RAB30,GRIA1,GRIA4,GRIK2,GRM2,KAT7,DDX19B,ELOVL5,SCRG1,HMGCR,HNRNPK,HSF2,IL6ST,JAK1,KCNJ9,KIF2A,KIF5A,ARHGAP12,NCOA7,CHIC1,MEF2C,MEIS2,KCTD6,MGAT3,MOBP,DBNL,MXI1,NBL1,NF1,NOVA1,KCNK10,PDE3A,PDPK1,CAMKV,PIK3R1,KCTD15,PACSIN1,POLR2F,PPP2R5E,KANSL1,PRKAB2,PRKCB,MAPK8,PTCH1,RAB5B,RAD51D,KHDRBS2,REV3L,GTDC1,RFX5,RIT2,SATB1,SCN3A,CASC3,ITSN1,BTBD7,ATF7IP,EPC1,MYT1L,KDM3A,GLT8D1,PEG10,KIF1B,DDN,POGZ,ANKRD12,FBXW11,SATB2,AHCYL2,AP4E1,HHIP,RGMB,NR2C2,RUSC1,ANKS1B,CADM2,NAV3,RTN4,CERS6,GAN" MicroRNA hsa-miR-483-5p:mirSVR_lowEffct hsa-miR-483-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.69E-68 3.19E-64 2.29E-67 2.11E-66 189 847 "TTYH1,ACHE,GPRIN1,NDRG3,NDRG2,OSBPL1A,SORCS2,FAM135A,CCDC146,KCNAB2,PHYHD1,BCAS1,PPFIA3,CPNE5,CDK13,MARK4,ASPH,CHID1,STX16,SLC2A11,ALDH7A1,CADM3,ADAM23,ADGRB2,RGS11,BLM,RAB29,CDK5R2,CACNB2,KALRN,PTBP2,TRIM41,BRSK2,RHBDL1,CBS,ZBED1,NOG,ADGRG1,SOCS6,DLGAP3,NRXN1,CLTA,TMEM59L,MAP4K4,ABI3BP,ENTPD4,ANKRD44,ABCG1,MAML1,CEP170,TMEM130,POM121,SGSM2,SLC29A4,DPYSL2,GNE,DNM1L,FIS1,PHF20L1,SUGP2,RASA4,IRAK4,DNAJC27,TLR7,SIRPB1,KATNAL1,CD320,HSPA12B,FAM198B,ZNF461,WAC,CHST15,GTF2IRD2,SEMA6C,SORBS1,CINP,TPK1,ARFGAP2,ZNF605,KHDRBS3,KBTBD12,FAM120B,KIAA1841,C1QL1,ZNF276,TNRC6A,KDM2B,GRM7,CLASRP,RNF165,MFSD2A,LINC01551,SLC2A6,PTGDR2,MAN1B1,HMGCL,AGBL5,IRF8,RBPJ,USP54,INPP5B,ITPKB,KCNJ5,KCNK2,KCNK3,LIMS1,LMO1,GPR155,MAOB,MARK3,SRSF12,NDUFA5,NKX2-2,NPTX2,PCBP3,OPHN1,LOC100128398,DPY19L2P2,OLA1,ZNF655,PNMA3,ANKRD16,CDIP1,POU6F1,SYTL2,GON4L,SNRK,MTMR10,CCDC40,PLEKHB2,ZNF793,RASGRF2,KHDRBS2,GSTCD,SNX22,KCNIP2,CLIP1,RYR3,ELMOD1,CASC3,ITSN1,FNDC3A,NUBPL,SMTN,SLC8A3,NAPB,MAST1,IGSF9B,SNRPN,SOX5,ZSWIM8,BEX1,KIF1B,INKA2,SEPT8,RGL1,DIP2A,STAC2,SUPT5H,DNMBP,PDLIM2,SMG6,PCDHB15,OBSL1,ZNF106,TMPO,CDK20,NPL,ZNF346,PRMT8,PPIL6,TSC1,HSPBP1,CLHC1,SGK3,PLEKHH2,MTCH1,BEST1,RICTOR,MKRN3,ZBTB16,PCBP1-AS1,MEIS3,HPS4,SIGLEC10,SLC17A7,SLC17A6,KAT6A,RNF170" MicroRNA hsa-miR-320a:PITA hsa-miR-320a:PITA_TOP PITA 7.45E-68 4.18E-64 2.99E-67 2.75E-66 142 481 "NDRG3,FMNL2,ERMN,UNC5A,PCDH19,SEMA6A,SHTN1,ARHGAP5,CDK13,ZBTB10,TMEM108,BTRC,CA8,CACNB4,VXN,LDB2,FMNL3,CDH2,ZMYM4,FOXN3,CHGA,SLC4A7,BAG4,CREB5,RIMS4,PPP1R16B,FAM131B,FRMPD4,HDAC4,TOX,DBN1,ARMCX2,MYEF2,RHOBTB1,SMG7,DLG2,DLX1,CALN1,NR1D2,GOLT1B,SEMA3D,CELSR3,GPR61,KMT5B,EGR3,PLXNC1,PAN3,EFS,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,TACC2,FAM49B,FUT9,STAG2,CAB39,DNER,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,GPR88,PDE3A,OLA1,MAGEL2,TNPO2,MED1,MINDY2,PPP2R2C,CEP41,PTPRG,FAM120C,TMEM255A,SLC25A36,FBXW7,HUNK,WLS,SEMA6D,PPP1R9A,FBXO11,SLITRK3,BTBD3,WDR47,PALLD,TMCC1,MYT1L,SOX11,LMO3,POGZ,SS18,NCDN,MAPK8IP3,KANK1,ATP11A,CAMTA1,CAMSAP2,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,ZFP91,KAT6B,TPD52L2,TPM3,TPM4,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZIC3,ZSCAN26,WNK1,EMSY,PRTFDC1,SLC17A6,PAK5" MicroRNA hsa-miR-320b:PITA hsa-miR-320b:PITA_TOP PITA 7.45E-68 4.18E-64 2.99E-67 2.75E-66 142 481 "NDRG3,FMNL2,ERMN,UNC5A,PCDH19,SEMA6A,SHTN1,ARHGAP5,CDK13,ZBTB10,TMEM108,BTRC,CA8,CACNB4,VXN,LDB2,FMNL3,CDH2,ZMYM4,FOXN3,CHGA,SLC4A7,BAG4,CREB5,RIMS4,PPP1R16B,FAM131B,FRMPD4,HDAC4,TOX,DBN1,ARMCX2,MYEF2,RHOBTB1,SMG7,DLG2,DLX1,CALN1,NR1D2,GOLT1B,SEMA3D,CELSR3,GPR61,KMT5B,EGR3,PLXNC1,PAN3,EFS,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,TACC2,FAM49B,FUT9,STAG2,CAB39,DNER,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,GPR88,PDE3A,OLA1,MAGEL2,TNPO2,MED1,MINDY2,PPP2R2C,CEP41,PTPRG,FAM120C,TMEM255A,SLC25A36,FBXW7,HUNK,WLS,SEMA6D,PPP1R9A,FBXO11,SLITRK3,BTBD3,WDR47,PALLD,TMCC1,MYT1L,SOX11,LMO3,POGZ,SS18,NCDN,MAPK8IP3,KANK1,ATP11A,CAMTA1,CAMSAP2,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,ZFP91,KAT6B,TPD52L2,TPM3,TPM4,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZIC3,ZSCAN26,WNK1,EMSY,PRTFDC1,SLC17A6,PAK5" MicroRNA hsa-miR-320d:PITA hsa-miR-320d:PITA_TOP PITA 7.45E-68 4.18E-64 2.99E-67 2.75E-66 142 481 "NDRG3,FMNL2,ERMN,UNC5A,PCDH19,SEMA6A,SHTN1,ARHGAP5,CDK13,ZBTB10,TMEM108,BTRC,CA8,CACNB4,VXN,LDB2,FMNL3,CDH2,ZMYM4,FOXN3,CHGA,SLC4A7,BAG4,CREB5,RIMS4,PPP1R16B,FAM131B,FRMPD4,HDAC4,TOX,DBN1,ARMCX2,MYEF2,RHOBTB1,SMG7,DLG2,DLX1,CALN1,NR1D2,GOLT1B,SEMA3D,CELSR3,GPR61,KMT5B,EGR3,PLXNC1,PAN3,EFS,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,TACC2,FAM49B,FUT9,STAG2,CAB39,DNER,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,GPR88,PDE3A,OLA1,MAGEL2,TNPO2,MED1,MINDY2,PPP2R2C,CEP41,PTPRG,FAM120C,TMEM255A,SLC25A36,FBXW7,HUNK,WLS,SEMA6D,PPP1R9A,FBXO11,SLITRK3,BTBD3,WDR47,PALLD,TMCC1,MYT1L,SOX11,LMO3,POGZ,SS18,NCDN,MAPK8IP3,KANK1,ATP11A,CAMTA1,CAMSAP2,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,ZFP91,KAT6B,TPD52L2,TPM3,TPM4,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZIC3,ZSCAN26,WNK1,EMSY,PRTFDC1,SLC17A6,PAK5" MicroRNA hsa-miR-320c:PITA hsa-miR-320c:PITA_TOP PITA 7.45E-68 4.18E-64 2.99E-67 2.75E-66 142 481 "NDRG3,FMNL2,ERMN,UNC5A,PCDH19,SEMA6A,SHTN1,ARHGAP5,CDK13,ZBTB10,TMEM108,BTRC,CA8,CACNB4,VXN,LDB2,FMNL3,CDH2,ZMYM4,FOXN3,CHGA,SLC4A7,BAG4,CREB5,RIMS4,PPP1R16B,FAM131B,FRMPD4,HDAC4,TOX,DBN1,ARMCX2,MYEF2,RHOBTB1,SMG7,DLG2,DLX1,CALN1,NR1D2,GOLT1B,SEMA3D,CELSR3,GPR61,KMT5B,EGR3,PLXNC1,PAN3,EFS,ETV1,EYA1,NRN1,PRKAG2,MEX3B,FLNC,TACC2,FAM49B,FUT9,STAG2,CAB39,DNER,ARFIP1,PPARGC1A,MIER3,NEGR1,SMAP1,CDH20,IPO5,SYTL4,PACRG,MAT2A,CHIC1,MEIS2,KITLG,MITF,MKLN1,MN1,MXI1,MYO6,NEXMIF,CNOT4,NPTX2,GPR88,PDE3A,OLA1,MAGEL2,TNPO2,MED1,MINDY2,PPP2R2C,CEP41,PTPRG,FAM120C,TMEM255A,SLC25A36,FBXW7,HUNK,WLS,SEMA6D,PPP1R9A,FBXO11,SLITRK3,BTBD3,WDR47,PALLD,TMCC1,MYT1L,SOX11,LMO3,POGZ,SS18,NCDN,MAPK8IP3,KANK1,ATP11A,CAMTA1,CAMSAP2,FBXW11,MGRN1,TCF4,SATB2,CLASP1,PUM2,ZMAT3,HEY1,ZFP91,KAT6B,TPD52L2,TPM3,TPM4,FAM155A,UBE3A,OSBP2,VLDLR,XPO1,PCDH20,ZIC3,ZSCAN26,WNK1,EMSY,PRTFDC1,SLC17A6,PAK5" MicroRNA hsa-miR-4320:mirSVR_highEffct hsa-miR-4320:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-68 5.10E-64 3.64E-67 3.35E-66 178 757 "KCNH8,NCKAP5,ARID1A,ADARB2,TMEM132B,BRAP,SLC12A5,HFM1,FAM135A,AMPD3,MAP4K3,MAGEE2,AMER3,APP,LGR5,ARNTL,DPY19L3,CCNH,INA,CHGA,DLGAP3,AKAP6,COL9A1,AHCTF1,SMARCAL1,CREM,ANKRD44,CS,SEC24C,FAM169A,GREB1,RUBCN,EARS2,KIAA0586,AIF1L,ZEB2,ELMO1,COPS7A,SNAP91,FAM107B,DLG2,DLG3,E2F6,EDIL3,FAM135B,FCF1,RASGRP1,OPTN,SUGP2,RASA4,ELN,C8orf37,KCNMB2,CEP85L,F5,TAOK3,STRADA,FDFT1,BAIAP2,IP6K2,FOLH1,SMC2,UFM1,STAU2,TBR1,GABRA1,MYOZ2,TUBGCP4,SULT1C4,MALT1,TXNL4A,ZNF638,LUZP2,GNAO1,GOLGB1,PRUNE2,RAPGEF4,GRIA1,GRIA2,GRIA4,CIT,RNF165,AP4S1,SOX21,ARHGAP19,EID2B,MSL1,KCNK1,KCNN2,KLRC2,STXBP5,INSYN2,SFXN5,SYT9,IL17D,MEIS1,CD200,SCG3,MYT1,NAP1L1,NAP1L3,NELL1,NEUROD2,NF1,CNOT4,NPY,NPTX2,NUCB2,OCRL,P2RX7,SNTG1,PCDH9,CDK18,GNG2,PRKAB2,RASGEF1B,PRKACB,EPDR1,MAPK10,HYDIN,WBP1L,LAMA1,MDGA2,PIGG,TMEM260,PTPRE,RAP1GDS1,OXR1,DPF2,SLC25A36,RIC8B,EXD2,CARF,NEK11,ZC3H14,ACER3,ZNF331,SCN7A,ZFP2,WDR37,TET1,ANKRD36,SOX2,SOX5,KDM4C,KIF1B,C11orf87,TTBK2,JMJD6,NUDT10,TAL1,EHBP1,TCF7,TPCN2,PCDHB9,AHCYL2,HHIP,TIAM1,ERCC6L2,C5orf64,TNS1,TP53BP2,SYNPO2,PLPPR2,ZIC1,LYPD6,ANKS1B,WNK1,CA10,EMSY,CSDE1,PDSS2,UBE3B,JMJD1C,TIGD6,KLHDC1,CBLN2,SPATA13" MicroRNA hsa-miR-654-3p:mirSVR_highEffct hsa-miR-654-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.39E-68 5.28E-64 3.77E-67 3.47E-66 196 910 "ACADM,NCKAP5,ADCY2,SLITRK1,BRAP,KIAA1211,PTCHD1,BEND6,ZNF608,CC2D2A,TAOK1,ALCAM,ABCD2,PHF12,APP,MIER1,CDK10,CAPRIN2,ASPH,DDX3Y,ATP1B3,NRP2,SYNJ1,JAZF1,CACNA1I,IL33,CACNB4,CAST,CCKBR,MTMR7,DGKI,CDC42,CDH10,CDH18,CLGN,COPB2,B4GALT6,NRXN1,FAM189A2,NIPBL,COL4A5,BTF3L4,SLC4A8,CP,CLIP3,ABCG1,UBXN2A,RIMS2,HDAC9,ARHGAP24,ZNF337,ZEB2,ELMO1,BLOC1S6,NTM,GRIN3A,DMTF1,PDCD6IP,FAM13A,EGR3,TMEM35A,STARD3NL,EIF1,TMEM74,ETV1,CLVS1,ZNF461,FCGR1A,FGFR1,FLT1,SORBS1,KHDRBS3,NSG1,GABRA1,GABRB1,ILDR2,AHCYL1,GALR1,DISC1,SULT1C4,PPARGC1A,RAB30,GLS,MSL3,ZNF638,GPD2,PCLO,RAPGEF4,RFFL,GRIK2,FAM19A2,BVES,ADAMTS6,HPSE2,MYLK2,ZNF546,ZIC5,USP54,SCIN,DIPK1A,ITGAM,ITGAV,KCNMA1,KLRC2,LAMP2,LSS,MAN2A2,MOBP,MSR1,SCG3,ZNF92,NCAM1,RCOR2,NEFM,NELL1,NUCB2,OLR1,JAKMIP1,PCDH18,MAPKAP1,ING3,PACSIN1,PPP3CA,GRAMD1C,HYDIN,CNNM2,SIDT1,QRICH1,PTPN13,ZNF615,CEP97,ARID4A,ZYG11B,TTLL7,TMLHE,SYNDIG1,ABCA11P,SCN8A,SCP2,CPEB3,SLC6A8,ZNF430,SEPHS1,SLC8A3,CPEB4,IFT122,UNC80,BDP1,KIF1B,PBLD,STOX1,SSTR2,LRRC4,FAM208A,UNC5D,ALG1,ADGRL3,TBL1X,SATB2,ZEB1,WASHC4,WDR7,PUM2,FAM200B,ITGB3BP,HHIP,TJP1,HEY2,TMPO,TRIO,KCNE5,TSC2,SSBP2,FAM155A,UBE2H,PITPNB,OSBP2,RICTOR,ZNF708,PLPPR5,CA10,CADM2,EVI5,HPS4,SIGLEC10,PCDH15,SNX27,FIP1L1,WIPF2,MPPE1,PARP11,FXR1,NETO2,NETO1,SLC4A10,FAM198A" MicroRNA hsa-miR-3192:mirSVR_highEffct hsa-miR-3192:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.04E-67 5.86E-64 4.18E-67 3.85E-66 189 850 "KCNH8,GALNT16,SLC12A5,UNC5A,ADORA3,KIF6,CDC42BPA,PI16,SUGT1P4-STRA6LP-CCDC180,API5,MADD,ARRB1,LINC00173,MARCH3,N4BP2L1,CARMIL3,SEC11C,CFLAR,MYRF,CACNB2,CCK,CD86,TMEM257,CDH18,LGI1,PPT2,KIAA1549L,FBXO7,TMEM155,CNTN1,BTF3L4,SLC4A8,CLIP3,TRIM69,CS,SNCAIP,CFAP61,CTNND2,RUBCN,CYBB,HDAC9,FGFR1OP2,DCAF8,TMEM170A,TOMM20,HEPH,ALKBH8,SMG7,GRIN3A,DNM1L,GOLT1B,WDPCP,ANKRD46,SIDT2,EGFR,ABI2,GOLGA7,EPHB1,SRRM1,MRPL37,RTN3,F8,TUBA1B,RACK1,FDFT1,PPP1R1B,FGF14,FGFR1,CAP2,FOLR2,COQ5,USP21,ARFGAP2,STAU2,GABRA1,AHCYL1,GALC,ERAP1,C15orf41,KIAA1841,ALDH1L1,TUBGCP4,ADAM28,GGT7,GHR,KIRREL3,GLI2,TOX3,POLL,LOXL3,PRRC2B,PRUNE2,PCLO,GRIA2,GRM7,LINC00839,CLASRP,RNF165,RABL2A,NXPH2,ATXN2L,HPSE2,HMGCR,AGBL5,ZNF678,LRRTM1,KCNJ3,KCNMA1,L1CAM,PAXBP1,MARK1,MAT2A,MEIS2,PPM1L,XRRA1,MT1M,MYO6,NF1,SLC11A2,ODF2,OLR1,PRTG,PDE4D,PDYN,XRN1,PLP1,RC3H2,SEPT4,NXPH1,MED1,PRKCZ,WDR25,PSMD13,CNTLN,PLPPR1,TMEM260,FAM120C,PPP2R3C,DBX2,GAL3ST4,GTDC1,RFX4,UBR7,RNF220,EXD2,KIRREL1,CCDC25,FBXW7,RTKN,SEMA6D,FNIP1,GALNT10,CTXN2,WDR47,LRRC55,ATF7IP,SNCA,SOX5,LMO3,TAB2,NKAIN2,AJAP1,FGD4,SYN2,RPGRIP1L,HIF3A,ITGB3BP,AP4E1,C9orf85,ZNF384,TRO,FNDC5,RFTN2,MTCH1,MEAF6,CCDC14,TRIM9,LYPD6,ZNF138,STOX2,HPS4,GAL3ST3,WIPF2,PHTF2,ACTR3B,ZNF248,FRMD6,AP3B2,PRRT4" MicroRNA hsa-miR-212:PITA hsa-miR-212:PITA_TOP PITA 1.26E-67 7.06E-64 5.03E-67 4.63E-66 120 338 "ARID1A,ELFN2,PCDH19,OSBPL8,SEMA6A,SEMA4G,TMEFF1,DDX3Y,FUBP1,PTBP2,DCLK1,LARGE1,CFL2,FOXN3,RAB28,HECTD1,ARMC8,CREB5,DOCK4,GAPVD1,ELMSAN1,ZEB2,POM121,SRGAP3,SEC16A,DUSP9,E2F5,RBM12,EPB41,NCALD,ETV1,NRN1,PRKAG2,FOXO3,AFF2,ARFGAP2,OGA,DKK3,RAPGEF6,SALL3,GHR,C1QL1,GPD2,GRM3,FAM19A2,HAS2,SMAP1,TJAP1,LRRTM3,KCNA6,KCNK2,PACRG,MAPT,MARK1,MEF2C,MEIS2,HNRNPM,NFIA,NFYA,NOVA1,NRCAM,KSR2,CDK14,PIK3R1,EPB41L4B,MED1,PPP2R5C,PPP2R5E,MAPK3,FAM184A,RDX,GTDC1,RFX3,ZFHX4,SETD5,LGR4,SALL1,SEMA6D,CSRNP3,ATXN1,SCN2A,SCN3A,LRRTM4,SOX6,FAM81A,RPH3A,EPN2,SLC6A1,SEPHS1,CCDC88A,SMARCA4,SOX3,SOX5,SOX11,MYCBP2,CDK19,COLGALT2,SS18,SEPT8,SEMA4A,CAMTA1,CAMSAP2,ADGRL3,TCF4,PUM2,SIRT1,HHIP,SLC44A1,HEY1,TRPS1,TSN,HIRA,SGK3,WIPF1,ZBTB14,NDRG4,CSDE1,RGS7BP,FXR1,ST8SIA2" MicroRNA hsa-miR-132:PITA hsa-miR-132:PITA_TOP PITA 1.26E-67 7.06E-64 5.03E-67 4.63E-66 120 338 "ARID1A,ELFN2,PCDH19,OSBPL8,SEMA6A,SEMA4G,TMEFF1,DDX3Y,FUBP1,PTBP2,DCLK1,LARGE1,CFL2,FOXN3,RAB28,HECTD1,ARMC8,CREB5,DOCK4,GAPVD1,ELMSAN1,ZEB2,POM121,SRGAP3,SEC16A,DUSP9,E2F5,RBM12,EPB41,NCALD,ETV1,NRN1,PRKAG2,FOXO3,AFF2,ARFGAP2,OGA,DKK3,RAPGEF6,SALL3,GHR,C1QL1,GPD2,GRM3,FAM19A2,HAS2,SMAP1,TJAP1,LRRTM3,KCNA6,KCNK2,PACRG,MAPT,MARK1,MEF2C,MEIS2,HNRNPM,NFIA,NFYA,NOVA1,NRCAM,KSR2,CDK14,PIK3R1,EPB41L4B,MED1,PPP2R5C,PPP2R5E,MAPK3,FAM184A,RDX,GTDC1,RFX3,ZFHX4,SETD5,LGR4,SALL1,SEMA6D,CSRNP3,ATXN1,SCN2A,SCN3A,LRRTM4,SOX6,FAM81A,RPH3A,EPN2,SLC6A1,SEPHS1,CCDC88A,SMARCA4,SOX3,SOX5,SOX11,MYCBP2,CDK19,COLGALT2,SS18,SEPT8,SEMA4A,CAMTA1,CAMSAP2,ADGRL3,TCF4,PUM2,SIRT1,HHIP,SLC44A1,HEY1,TRPS1,TSN,HIRA,SGK3,WIPF1,ZBTB14,NDRG4,CSDE1,RGS7BP,FXR1,ST8SIA2" MicroRNA hsa-miR-3134:mirSVR_highEffct hsa-miR-3134:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.61E-67 1.47E-63 1.05E-66 9.63E-66 184 812 "ABAT,KCNH8,ACTN2,XKR4,CSMD3,FMNL2,KIAA1211,ADORA3,HECW2,PCDH19,RTL9,ARHGAP20,FAM135A,SUGT1P4-STRA6LP-CCDC180,PHYHD1,PPP4R4,CADPS,DYNLL1,ZNF583,ADAM23,BCL7A,ZNF599,CFLAR,CACNB2,CAST,CCNH,MTMR7,SRSF11,CHM,CHN2,RAB3C,NRXN1,NIPBL,ARHGEF6,LETMD1,COL9A3,RCHY1,RTTN,LRIG1,LRRC3B,KIAA0408,DOCK4,MYADM,TOX,ZNF337,GIT2,ZC3H11A,RHOBTB1,SMG7,RABGAP1L,FAM107B,DLG2,GRIN3A,RAB39B,DTNA,DNM1L,ANKRD46,PHF20L1,SUGP2,LPAR6,EIF1,IGSF6,ETV1,RTN3,STRADA,SLC9B2,POLR1B,SEMA4D,FLT1,SMC2,ATP2C1,ST6GALNAC3,DOT1L,STAG2,ZMYND11,ERAP1,MSTN,PCDH17,TNRC6A,KCNMB4,GPD2,FUT10,GRIA2,GRIA4,ADAMTS8,GRM1,GRM7,LINC01551,FAM222A,VSIG4,MSL1,LRRCC1,KIAA1755,IL12A,KIF5A,KIF5C,HECTD2,MAN2A2,TM6SF1,MOG,ADAM22,BCO1,MSR1,RSPO2,MYT1,P2RY13,NCAM1,NF1,NPPA,NUMA1,OLR1,GLIPR1L2,PBX1,PCDH9,SNX10,MTRF1L,STRN3,NECAB2,MAGEL2,ING3,EPB41L4B,PPARA,PPP2R5E,PKN2,MAPK8,GRAMD1C,TMEM260,PTPRH,C1orf109,ZNF615,RNASEL,ZNF532,TMLHE,NCBP3,LRFN5,SCP2,ASIC4,ZFP2,SH3GL2,KIF16B,SLITRK3,NLGN1,ZNF365,PREX2,SLC8A3,KBTBD4,ELMO2,SPHKAP,SLIT1,CPEB4,MAST1,SMARCE1,SNCA,SNRPN,MYO16,HECW1,NFASC,ATP10B,SSTR1,SSTR2,NKAIN2,VAMP1,TAL1,ANO4,WDR7,C18orf54,LEFTY2,ERCC6L2,C5orf64,KAT6B,SSBP2,CLDND1,PCDH20,ZNF28,TRIM9,GPR158-AS1,FSTL5,ANKS1B,MEIS3,LRP8,MDH1B,CAB39L,JMJD1C,RNF170" MicroRNA hsa-miR-1972:mirSVR_highEffct hsa-miR-1972:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.69E-67 1.51E-63 1.08E-66 9.90E-66 178 762 "FMNL2,SLC12A5,PWWP2A,AMPD2,LRCH2,LGR5,BCHE,SYNJ2,MTMR2,CACNB2,NGB,VSTM2A,KYAT1,USP2,AIFM1,RAB33A,PPT2,LY86,CNN3,ARMC8,LETMD1,ABI3BP,CREM,CSNK1E,ATRNL1,EDRF1,NOS1AP,KATNAL2,IP6K1,YTHDC1,MYEF2,CEP170,PLPPR4,USP3,DPP6,PDCD6IP,FAM78B,DNM1L,SNX29,WDPCP,EGFR,EGR3,ING4,STARD3NL,EPB41L1,LRRC17,ETV1,RTN3,STRADA,KAT8,MED12L,FGF11,POLK,GALNT15,FAM120B,ZMYND11,JPH4,ZNF274,GAP43,GART,KIAA1841,TUBGCP4,ARFIP1,GGT7,NTNG2,GOLGB1,GRIA4,SERP2,GRM7,COQ10A,RNFT2,GUCY1B1,WIF1,HPSE2,BTBD17,KCND3,CLVS2,KCNK2,LAMP2,STMN1,LIMS1,MAN2A2,MAP2,MBD1,TM6SF1,MEIS1,KCTD6,KITLG,MOBP,ERICH3,COL28A1,NDP,PCBP3,NRDC,HCN1,NTRK2,ODF2,PDE1C,PDE4D,PDGFRA,PFKFB4,HERC2P3,PLCL1,POU3F2,PPM1B,PPP3CB,RASGEF1B,PRKACB,PKN2,MASP1,BCAS3,SIDT1,MDGA2,CNTLN,PTH1R,PTPRB,PTPRO,ZCWPW1,RASGRF2,ZMAT4,GTDC1,RGS4,ELP2,BAALC,HSD11B1L,NCBP3,NTNG1,HKDC1,NUBPL,SLC6A11,SLC12A4,ATF7IP,NAXD,RCOR3,SNRPN,MYO16,DOP1A,ZSWIM8,GLT8D1,MYCBP2,KIF1B,NPAS3,SS18,TTBK2,RGL1,SEPT3,ABCC8,PLCB1,C12orf76,TACR1,TAL1,FAM208A,WDR7,PCDHB4,PCDHB3,FRYL,AP4E1,HEY1,CSMD1,SYNPO2,METTL3,MGAT5B,CCDC136,RICTOR,TRIM9,ZNF45,LYPD6,ZNF189,ZFAND5,EMSY,LINC02210,ADAMTS9,MDH1B,SLC17A7,SMIM8,FRMD6,IFT88,NETO2" MicroRNA hsa-miR-196a:mirSVR_highEffct hsa-miR-196a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.73E-67 2.66E-63 1.89E-66 1.74E-65 182 798 "BRAP,SORCS1,ERMN,CC2D2A,MAP4K3,APAF1,UPRT,TNRC6C,MIER1,ARHGAP5,ARNTL,RASL11B,ATP1A2,ATP2A2,DOCK11,RAB29,CACNA1E,CACNB2,CALM1,PTBP2,SPAG9,LRBA,CDC27,CDH18,CCPG1,PPT2,FAM19A5,QKI,MAP4K4,FAM149A,AKAP6,ABI3BP,TBPL1,CHD1L,TRIM69,ATRNL1,PDE4DIP,CTNND1,PPP6R2,USP6NL,CYBB,BOC,HDAC9,GPRASP1,KIAA0586,HP1BP3,KLHL3,SMG7,SNAP91,WDPCP,EDNRB,MBNL2,ELAVL4,EPB41L2,LRRC17,WAC,EFEMP1,ZSCAN30,SLC9B2,FHL1,HPCAL4,RGPD5,ANKFY1,C2orf88,ATP2C1,SARAF,ZNF512,FYB1,GABRA2,GABRB3,ZMYND11,GALC,DISC1,DNER,NEU3,GHR,TOX3,GPM6B,PCLO,GRIA2,PRDM5,RNF165,PSIP1,DDX19B,ZNF385B,NME9,KCNJ10,SYTL4,MBNL1,SYT9,LRP1B,POC1B,ERICH3,RSPO2,MYO9A,PABPC1L2A,OPA1,OPCML,P2RY1,PDE3B,GPR85,PIK3C2A,ZNF655,A2ML1,XRN1,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R5E,PPP3CB,RANBP3L,SNRK,WDR25,ELOVL2,TMEM260,PTPRG,SH3TC2,ERI2,GTDC1,LGI2,RERGL,EXD2,C12orf49,RAVER2,ATP8B4,S100B,PRCD,FNIP1,CASC3,GALNT10,KIF27,CTXN2,RUFY2,SLC14A1,ELMO2,MYH15,PALLD,UNC80,RBM34,TRERF1,HECW1,KDM4C,RBM26,RAP1GAP2,LMO3,ITPRID2,DIP2A,KANK1,NECAB1,TAC1,FAM208A,SMG6,KLHL4,ANO4,ACSL6,ZEB1,SLC19A3,PUM2,SIK3,SIRT1,MTMR14,ERCC6L2,LRRC8A,TMPO,SYNPO2,TRPC3,TMEFF2,HIRA,GORASP1,BEST1,VSNL1,XRCC4,MKRN3,ANKS1B,SMARCAD1,CA10,STOX2,FAM13C,KAT6A,HNRNPA3,GAN" MicroRNA hsa-miR-3179:mirSVR_highEffct hsa-miR-3179:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.92E-67 2.77E-63 1.96E-66 1.81E-65 191 875 "CPNE2,ACLY,SLITRK1,SORCS1,OSBPL1A,APC,CACHD1,VAT1L,ASPH,DACT3,ZBTB10,NCOA1,ATP1A3,EIF4G3,STX16,ATP6V1G2,DCAF5,CDK5R1,DST,SYNJ1,WASF1,CACNB2,HAP1,TRIM41,SYT6,CERS5,INA,CDC25B,ZMYM4,CLGN,TAOK2,C7orf61,NRXN3,ZFYVE9,PPT2,ARHGEF6,CNTN1,AKAP6,LETMD1,RTTN,PNKD,SH2B1,ANKRD44,CLIP3,PDE4DIP,NRSN1,RUBCN,GAPVD1,HDAC4,CENPL,LIN54,SPOCK2,B3GAT3,C2CD2L,SMG7,KIF19,DLG4,DNM1,DMPK,SLC25A18,PDCD6IP,SNX29,PHC2,EFNA3,SUGP2,EIF1,HSD17B14,EPB41,MFSD10,EPHB1,RABEPK,SRRM1,SPEG,ETV1,DNAJC27,F8,TAOK3,ZSCAN30,STRADA,PPP1R1B,SLC9B2,GTF2IRD2,FGF1,FGF11,FGF12,CAMKK2,JPH4,GLYR1,PCDH11X,PSIP1,ATXN2L,ARHGAP36,AGBL5,TLX1,ZNF546,LRRC25,LRRCC1,KIAA1755,ITIH2,ITPKA,OLFM3,CLVS2,KIT,L1CAM,STMN1,ASPRV1,MBNL1,AFDN,MMP16,MRPL42,MX1,MYO9A,PABPC1L2A,NEK1,NOVA1,DNHD1,NPR2,IGSF11,PCDH9,PDPK1,PLIN1,SEPT4,EPB41L4B,SH3KBP1,POU3F4,PPM1B,PPP3CB,PRKACB,PKIA,PTAFR,SPDL1,TMEM145,RAB5B,PID1,RAD17,OXR1,ERI2,NUDT11,SETD5,CARF,CCDC25,SGSM1,ATAT1,ZNF568,FAM192A,CSRNP3,SHMT2,R3HDM2,DHX30,SMTN,SLC8A1,CCDC88A,SORCS3,RIMS1,SON,WDTC1,KIF1B,DDN,STOX1,STX1A,GANAB,PRRC2C,SYNE2,VAMP1,SEMA4A,MLST8,TAL1,ADGRL3,SMG6,SYNE1,CCDC173,PMS2CL,TIAM1,TPD52,TPM2,RFTN2,UBE3A,FAM181B,VGF,WIPF1,ZIC3,FMN2,NDRG4,WNK1,CA10,MDH1B,SNX27,ZNF248,SSPN,PIANP,JPH3" MicroRNA hsa-miR-449a:PITA hsa-miR-449a:PITA_TOP PITA 8.25E-67 4.64E-63 3.28E-66 3.02E-65 112 295 "ABR,ASIC2,TMCC3,USP31,GPR158,LRRC7,ALCAM,ANK3,PKP4,CNTNAP1,TMEFF1,NCOA1,MTMR9,DPY19L3,SYNJ1,JAZF1,WASF1,CACNA1E,CALB1,INA,EVI5L,NUMBL,NRXN2,MAP4K4,AKAP6,SLC25A27,SLC4A7,MYRIP,CLOCK,CREB5,CSNK1G3,CNTNAP2,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,FOXG1,AGAP2,ZCCHC17,GABRA3,BRPF3,CPLX2,MSTN,LOXL3,PCLO,TPPP,GRID1,GRM7,CELF3,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,PDGFRA,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RALGDS,RET,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,TRIM67,FAM126B,SOX10,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,CNTN2,ATMIN,SATB2,TCF12,DOCK9,AHCYL2,THRA,RELL2,TPD52,FNDC5,POLR3H,SYNC,SLC30A3,NAV3,CERS6" MicroRNA hsa-miR-449b:PITA hsa-miR-449b:PITA_TOP PITA 8.25E-67 4.64E-63 3.28E-66 3.02E-65 112 295 "ABR,ASIC2,TMCC3,USP31,GPR158,LRRC7,ALCAM,ANK3,PKP4,CNTNAP1,TMEFF1,NCOA1,MTMR9,DPY19L3,SYNJ1,JAZF1,WASF1,CACNA1E,CALB1,INA,EVI5L,NUMBL,NRXN2,MAP4K4,AKAP6,SLC25A27,SLC4A7,MYRIP,CLOCK,CREB5,CSNK1G3,CNTNAP2,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,FOXG1,AGAP2,ZCCHC17,GABRA3,BRPF3,CPLX2,MSTN,LOXL3,PCLO,TPPP,GRID1,GRM7,CELF3,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,PDGFRA,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RALGDS,RET,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,TRIM67,FAM126B,SOX10,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,CNTN2,ATMIN,SATB2,TCF12,DOCK9,AHCYL2,THRA,RELL2,TPD52,FNDC5,POLR3H,SYNC,SLC30A3,NAV3,CERS6" MicroRNA hsa-miR-34a:PITA hsa-miR-34a:PITA_TOP PITA 8.25E-67 4.64E-63 3.28E-66 3.02E-65 112 295 "ABR,ASIC2,TMCC3,USP31,GPR158,LRRC7,ALCAM,ANK3,PKP4,CNTNAP1,TMEFF1,NCOA1,MTMR9,DPY19L3,SYNJ1,JAZF1,WASF1,CACNA1E,CALB1,INA,EVI5L,NUMBL,NRXN2,MAP4K4,AKAP6,SLC25A27,SLC4A7,MYRIP,CLOCK,CREB5,CSNK1G3,CNTNAP2,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,FOXG1,AGAP2,ZCCHC17,GABRA3,BRPF3,CPLX2,MSTN,LOXL3,PCLO,TPPP,GRID1,GRM7,CELF3,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,PDGFRA,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RALGDS,RET,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,TRIM67,FAM126B,SOX10,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,CNTN2,ATMIN,SATB2,TCF12,DOCK9,AHCYL2,THRA,RELL2,TPD52,FNDC5,POLR3H,SYNC,SLC30A3,NAV3,CERS6" MicroRNA hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA_TOP PITA 8.25E-67 4.64E-63 3.28E-66 3.02E-65 112 295 "ABR,ASIC2,TMCC3,USP31,GPR158,LRRC7,ALCAM,ANK3,PKP4,CNTNAP1,TMEFF1,NCOA1,MTMR9,DPY19L3,SYNJ1,JAZF1,WASF1,CACNA1E,CALB1,INA,EVI5L,NUMBL,NRXN2,MAP4K4,AKAP6,SLC25A27,SLC4A7,MYRIP,CLOCK,CREB5,CSNK1G3,CNTNAP2,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,ABCC5,E2F5,CELSR3,APH1A,RGS17,NRN1,ACSL4,SCML2,SUCO,FOXG1,AGAP2,ZCCHC17,GABRA3,BRPF3,CPLX2,MSTN,LOXL3,PCLO,TPPP,GRID1,GRM7,CELF3,MIER3,ZIC5,KITLG,MITF,MPP2,MYCN,ZC3H12B,PDE4B,PDGFRA,GPR85,STRN3,PKIA,PTPRD,TMEM255A,RALGDS,RET,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,TRIM67,FAM126B,SOX10,PEG10,ARHGAP26,DDN,POGZ,STAC2,SEPT3,ARHGEF9,SYT1,MTCL1,CAMTA1,CNTN2,ATMIN,SATB2,TCF12,DOCK9,AHCYL2,THRA,RELL2,TPD52,FNDC5,POLR3H,SYNC,SLC30A3,NAV3,CERS6" MicroRNA hsa-miR-4301:mirSVR_lowEffct hsa-miR-4301:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-66 5.83E-63 4.13E-66 3.80E-65 201 967 "RALGAPA1,ACADM,AS3MT,TMEM132B,PSMG3-AS1,TMCC3,ADD1,BRAP,SLC12A5,PWWP2A,DPP10,LRCH2,LCORL,SUGT1P4-STRA6LP-CCDC180,GPAM,BCAS1,TMEM263,SPTBN4,NUMB,RASL11B,ATP1A3,SLC4A4,NOL4,NAE1,C5,CA8,CACNB2,THSD7A,CANX,SLC25A14,HIP1R,CBLN1,MTMR7,SLIT2,C7orf61,FBXO7,TJP2,MAP4K4,ZFP28,CHD1L,CRY2,ABCG1,SOCS5,PDE4DIP,KIAA0040,CYBB,ARHGAP24,MATR3,TOMM20,CTIF,MYEF2,MFAP3L,COPS7A,KIAA0319,GSDME,SPOCK3,DLG3,HS3ST4,CPEB2,GNE,ABCC5,DNM1L,ABCC9,E2F5,EDNRB,SYT15,RASGRP1,EFNA3,SH3GLB1,ELAVL4,VPS13B,DMTN,EFEMP1,FCGR1A,FCGR3A,TOMM40L,FLYWCH1,USP16,ATP6V1H,CSPG5,TBR1,AP4B1,FYB1,GABRG1,GALC,DISC1,LRRC37A6P,CPLX2,GCNT2,SULT1C4,MSTN,GGTA1P,GLS,TNRC6A,CBX1,STON1,GRIA4,GRID1,FAM19A2,WIF1,MAEL,AGBL5,TCEAL6,ZNF181,DOCK7,ITGAM,KCND1,KCND3,L1CAM,SYTL4,FGFBP3,MEIS1,MOBP,DDX25,MTTP,MXI1,NAP1L3,NCAM1,NDUFA5,NEK1,NF1,DNHD1,NPTX2,SMIM11A,OCRL,CLDN11,GLIPR1L2,DPY19L2P2,PDE3A,PDGFRA,ENPP2,PDYN,PFKFB4,SNX10,HMGCLL1,PNMA3,STRN3,LRP12,TNPO2,PPP2R5E,PPP3CB,PKIA,MAPK9,MDGA2,PTCH1,ANKHD1,PTPRO,PID1,USP47,OXR1,GTDC1,RFX3,SEC61A2,SLC25A36,RNASEL,TMLHE,ROBO1,PCMTD2,EPHA10,WLS,SOX6,CASC3,ITSN1,FERMT1,HKDC1,CHD9,FBXO11,FNDC3A,SEC31A,SLC2A5,LRRC55,SLC6A7,SLC6A11,NAPB,NAXD,SMARCE1,IFT122,ANKRD36,SOX3,ZNF423,SPTAN1,NFASC,ITPRID2,SMOC1,NKAIN2,LRRC4,NECAB1,ADGRL3,EHBP1,PCDHGB7,C18orf54,SLC44A1,RBFOX2,DCBLD1,UBE3A,MEIS3,CAB39L,HNRNPA3,CASC15,TRAM2-AS1,ZNF248" MicroRNA hsa-miR-135b:PITA hsa-miR-135b:PITA_TOP PITA 1.42E-66 7.95E-63 5.62E-66 5.17E-65 136 449 "DPF1,INTS2,MTUS1,GPR158,OSBPL8,ALCAM,TRMT9B,ANK3,ANXA7,CNTNAP1,APC,GAS7,API5,ZFYVE28,ARNTL,PDE8B,NCOA1,DDX3Y,ATP2B2,ATP2B3,ARHGEF7,BSN,CACNA1D,KALRN,PTBP2,TRIM41,LDB2,ARHGEF2,KCNAB3,DLGAP2,FOXN3,ARHGEF6,PCYT1B,SLC4A7,ZNF385A,CREB5,CSNK1G3,SLITRK5,ARHGEF4,NRSN1,RIMS2,NOS1AP,FRMPD4,HDAC4,LONRF1,JAKMIP2,MYEF2,CEP170,DLG2,RAB39B,HIPK3,GOLGA7,EPB41,ERBB4,EFS,EXTL2,EYA1,WAC,ATP8A1,CAP2,SYT3,NBEA,FUT9,AHCYL1,B4GALNT1,CPLX2,CPLX1,GHR,GNG3,FERMT2,PSIP1,MIER3,NEGR1,KCND1,MAT2A,MEF2C,MEIS2,NEFM,NF1,NODAL,NPTX1,HCN1,GPR85,TNPO2,DRAM2,PPP2R5C,CEP41,DIRAS2,SNRK,ELOVL2,PTK2,PTPRD,RAB5B,RAP1GDS1,SETD5,PCMTD2,ATXN1,SCN2A,PPM1E,NTNG1,SMARCE1,RIMS1,MYT1L,ZCCHC24,TEX2,RGL1,KANK1,PLCB1,CAMTA1,ANO4,CUX2,WASHC4,PSD3,SIRT1,SLC44A1,FBXL16,TIAM1,MTMR14,TMEM9,KAT6B,RBFOX2,TRPC1,FNDC5,VLDLR,TMEM237,ZFAND5,EVI5,STMN4,ADAMTS9,ST7,PAK5,HNRNPA3,PHTF2,CAMK1G,MSRB3,SOCS4" MicroRNA hsa-miR-135a:PITA hsa-miR-135a:PITA_TOP PITA 1.42E-66 7.95E-63 5.62E-66 5.17E-65 136 449 "DPF1,INTS2,MTUS1,GPR158,OSBPL8,ALCAM,TRMT9B,ANK3,ANXA7,CNTNAP1,APC,GAS7,API5,ZFYVE28,ARNTL,PDE8B,NCOA1,DDX3Y,ATP2B2,ATP2B3,ARHGEF7,BSN,CACNA1D,KALRN,PTBP2,TRIM41,LDB2,ARHGEF2,KCNAB3,DLGAP2,FOXN3,ARHGEF6,PCYT1B,SLC4A7,ZNF385A,CREB5,CSNK1G3,SLITRK5,ARHGEF4,NRSN1,RIMS2,NOS1AP,FRMPD4,HDAC4,LONRF1,JAKMIP2,MYEF2,CEP170,DLG2,RAB39B,HIPK3,GOLGA7,EPB41,ERBB4,EFS,EXTL2,EYA1,WAC,ATP8A1,CAP2,SYT3,NBEA,FUT9,AHCYL1,B4GALNT1,CPLX2,CPLX1,GHR,GNG3,FERMT2,PSIP1,MIER3,NEGR1,KCND1,MAT2A,MEF2C,MEIS2,NEFM,NF1,NODAL,NPTX1,HCN1,GPR85,TNPO2,DRAM2,PPP2R5C,CEP41,DIRAS2,SNRK,ELOVL2,PTK2,PTPRD,RAB5B,RAP1GDS1,SETD5,PCMTD2,ATXN1,SCN2A,PPM1E,NTNG1,SMARCE1,RIMS1,MYT1L,ZCCHC24,TEX2,RGL1,KANK1,PLCB1,CAMTA1,ANO4,CUX2,WASHC4,PSD3,SIRT1,SLC44A1,FBXL16,TIAM1,MTMR14,TMEM9,KAT6B,RBFOX2,TRPC1,FNDC5,VLDLR,TMEM237,ZFAND5,EVI5,STMN4,ADAMTS9,ST7,PAK5,HNRNPA3,PHTF2,CAMK1G,MSRB3,SOCS4" MicroRNA hsa-miR-24-1*:mirSVR_lowEffct hsa-miR-24-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.46E-66 8.23E-63 5.81E-66 5.35E-65 181 795 "ASPHD1,SORCS1,ADORA2A,OLMALINC,OSBPL8,BCAR3,SYT13,CDC42BPA,LRCH2,APAF1,APC,TNRC6C,CDC14B,IGDCC4,SPTBN4,ARHGAP5,STK33,ASTN1,RIPK1,DCAF5,LINC00906,MMD2,CACNA1E,PTBP2,CAMK2A,CAST,P2RX6,ARHGEF2,CDH10,LRRFIP1,IGFN1,SLC4A7,SEC31B,RBM39,SNCAIP,DZIP3,ARHGAP32,FGFR1OP2,MATR3,IP6K1,AIF1L,ZEB2,HEPH,RHOBTB1,EXOG,DNAH9,ABI1,ATN1,E2F6,EDIL3,CERCAM,RCAN2,ENPP6,ANKRD13B,RRAGB,FAM198B,EFEMP1,CEP78,CAMSAP1,SYNCRIP,IQCG,ATP6V1H,ZNF605,HBS1L,GALR1,DISC1,ATP8A2,DBF4,TNRC6A,PCDH11X,LILRB4,GPD1,GPM6A,GRM5,TMEM25,FAM107A,NCKAP1L,ARHGAP36,ELOVL5,HSD17B1,LRRC75A,HSP90AA1,HTR5A,FAM95B1,IL6ST,KCNH1,KCNJ10,KCNMA1,TTYH2,VWA5A,HECTD2,MDM4,MEIS1,SCAMP5,MN1,MPP2,MRPL42,CCDC80,N6AMT1,MYO7A,NEUROD1,NUMA1,OPHN1,P2RY1,GLIPR1L2,GPR173,GPR85,ZDHHC8,GPSM2,NLE1,PLCB2,PRRX1,PPP2R5E,PRKAB2,PKN2,MDGA2,TMEM104,PTN,PTPRE,SUSD4,RDX,ZYG11B,RFX4,SLC25A36,RORB,NEK11,KIAA0895L,ABCA11P,KCNIP3,ZNF568,TRAPPC13,ATXN2,IL17RB,PEAR1,MRAS,FNDC3A,PEX26,WDR47,SLC8A3,CCDC88A,KBTBD4,SLCO1A2,DOP1A,WDTC1,SOX1,ZC3H13,DBNDD2,SPTB,ZBTB43,NFASC,PBLD,ELOVL4,ADAMTS17,FNDC9,SYN2,SYP,SYPL1,CAMTA1,UNC5D,ATMIN,SLC44A1,TMPO,FAM124A,TP53BP2,CHST5,PRMT8,TRIO,TRPC1,TRPS1,PPIL6,SSBP2,AMOT,FLRT2,ZIC3,ZBTB16,ZNF154,PCBP1-AS1,RGMA,VPS35L,SLC17A6,FZD3" MicroRNA hsa-miR-302d:PITA hsa-miR-302d:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-520c-3p:PITA hsa-miR-520c-3p:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-302c:PITA hsa-miR-302c:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-302e:PITA hsa-miR-302e:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-520a-3p:PITA hsa-miR-520a-3p:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-520b:PITA hsa-miR-520b:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-520e:PITA hsa-miR-520e:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-520d-3p:PITA hsa-miR-520d-3p:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-373:PITA hsa-miR-373:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-372:PITA hsa-miR-372:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-302a:PITA hsa-miR-302a:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-302b:PITA hsa-miR-302b:PITA_TOP PITA 2.38E-66 1.34E-62 9.37E-66 8.63E-65 150 551 "PWWP2A,SNX30,PTCHD1,MTUS1,GPR158,AK2,SPOP,APBB2,APP,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,DCLK1,DLGAP2,CFL2,B4GALT6,KMT2C,SLC25A27,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,ARHGEF10,SOCS5,RUBCN,HDAC4,TOX,RASSF2,IP6K1,SIRPA,PLEKHM1,MFAP3L,HP1BP3,ZC3H11A,HS3ST4,DMTF1,DRD1,E2F5,HIPK3,EFNB3,MBNL2,KMT5B,ELAVL2,PAN3,DNAJC27,EZH1,MED12L,SUCO,FOXO3,AFF2,PHYHIPL,PCDH17,MAP7D2,GPM6A,PCLO,KLF12,MIER3,HLF,C5orf24,SCRT2,KCNK2,SYTL4,NCOA7,MARK1,CHIC1,MEF2C,MXI1,MYCN,NEUROD1,NNAT,NRCAM,OPCML,OPHN1,GPR137C,PCDH9,PFKP,PLCL1,TRHDE,PRRX1,EPB41L4B,PPARA,KANSL1,PKN2,MAPK9,SNRK,TMEM260,PTPRD,OXR1,ARID4A,RDX,GTDC1,SLC25A36,ALG9,TMEM100,LGR4,AMER2,SBF1,ATXN1,SCN2A,FNIP1,MAGI3,FBXO11,FNDC3A,SLITRK3,WDR37,TET1,RCOR3,PALLD,TMCC1,MYT1L,CDK19,NPAS3,LMO3,ERBIN,RGL1,STXBP1,FGD4,CAMTA1,TAL1,CUX2,TRIM2,ZFPM2,AKTIP,TIAM1,DDHD1,ZFP91,NR2E1,TNS1,NR2C2,TRPS1,VLDLR,LYPD6,SYNC,UPF3A,EMSY,CADM2,RGMA,PRDM8,PRDM10,WIPF2,PLSCR4,FAM13C,MARCH8,PAK5,DPF3,ST8SIA2" MicroRNA hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA_TOP PITA 2.69E-66 1.51E-62 1.06E-65 9.75E-65 137 458 "SLITRK1,ADCY6,SORCS1,NLGN4X,PCDH19,OSBPL8,SPOP,OGT,DPP10,NCOA1,ATP2B1,RNF182,NIPA1,BTRC,CA8,CACNA1E,CACNB4,CANX,MAP7,DLGAP2,NUMBL,CHN1,SYNPR,B4GALT6,NRXN2,TMEM184B,NIPBL,ARMC8,SLC4A7,IGDCC3,SLC32A1,CHD5,CTNND2,PUM1,SPOCK2,CTIF,ZEB2,MYEF2,CEP170,G3BP2,USP3,PHC2,RBM12,YAF2,MBNL2,EGR3,SORBS3,TENM1,PAN3,EPB41L2,RASGRP2,ERBB4,SEC24B,MED12L,SYNCRIP,EVL,NBEA,KHDRBS3,GABRB3,MSTN,SPIN1,RAB30,ATF7,KAT7,SOX21,PSIP1,IGSF21,SLC6A17,KCND2,IPO5,MAT2A,SYT9,MKLN1,AFF1,SAMD5,MSI1,MYO5A,PABPC1L2A,NCAM1,NEUROD1,NTRK3,SDK2,FAT3,NXPH1,POU3F2,PPP2R5E,PPP3CB,RANBP3L,CEP41,GDPD1,FAM120C,RAB5B,GTDC1,FIGN,SPIN3,RPS6KA2,HUNK,KCNIP1,CLIP1,SEMA6D,SOX6,MYO18A,CHD9,CPEB4,SNAP25,FAM126B,FAM219A,FNBP1,SOX11,LMO3,STAU1,NECAB1,PRRC2C,SYT1,ANKRD28,MCF2L,RALYL,ARHGEF12,DICER1,CHST8,HHIP,FBXL16,TIAM1,TRPC1,TSC1,OSBP2,ZIC1,NDRG4,SMARCAD1,SLC30A4,STMN4,PRDM8,SNX27,KAT6A,HNRNPA3,MSRB3,FXR1" MicroRNA hsa-miR-593:mirSVR_highEffct hsa-miR-593:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-66 1.69E-62 1.18E-65 1.09E-64 186 841 "ELFN2,DSCAML1,ADORA3,KIDINS220,BEND6,ZNF608,PCDH19,WDR35,LRRC7,ALK,DPP10,CNTNAP1,GPAM,APOC1,DYNLL1,ATP2A2,ATP2B1,ADAM23,ADAM15,NRP2,MMD2,CACNA1E,THSD7A,KALRN,CAST,CD86,NOG,SRSF11,HECTD1,AKAP6,SLC25A27,TCEAL2,CP,CREM,SLC32A1,CLIP3,MROH8,SEC24C,ARHGEF10,SUSD5,PDE4DIP,UBXN2A,RIPOR2,EARS2,RASSF2,DGKG,DAPK1,ZEB2,HP1BP3,NTM,SGSM2,DLG2,EXOG,HS3ST4,DTNA,HIPK3,FCF1,EGR3,EPB41,RCAN2,EPHB1,ERBB2,MRPL37,DUSP27,EYA1,STRADA,KAT8,FGF11,CAP2,FOXM1,FOLH1,ZCCHC17,SMC2,USP21,KHDRBS3,ST6GALNAC3,CPLX2,KIAA1841,DNER,GBX2,HEPN1,GLS,LUZP2,DCLK2,LILRA1,ATP2B1-AS1,PTPN5,OPALIN,MSL1,MYLK2,IGSF1,INPP5B,LRRTM1,OLFM3,KCNC1,KCNJ10,LOC100128239,MAN2A2,SYT9,MEIS1,BLOC1S2,PTOV1,NDUFA5,NTRK3,NUCB2,GPR88,ZNF827,CDK18,ABCB1,ZNF655,SMIM7,PLXNB3,PRIMPOL,MAPKAP1,SEPT4,PPP2R5C,GON4L,CNTLN,PTHLH,OCIAD1,FAM66C,RPRD1A,SETD5,GSTCD,UEVLD,YJEFN3,KCNIP1,S100B,ZFP2,SCAF8,SH3GL2,SHC4,CHD9,CNKSR2,WDR47,SLC8A3,BTBD7,SLC22A4,ZFP1,MYH15,MBD5,BDP1,SOX10,SP4,TSPYL2,PBLD,SSTR1,ERBIN,STAC2,NSFL1C,KLHL7,ASTN2,SEMA4A,CAMTA1,ANO4,SATB2,TCF7,TCF12,SZT2,ARHGAP9,FRYL,CYB561A3,ITGB3BP,ASXL3,ERCC6L2,FAM124A,C5orf64,TNR,SEZ6L,PRMT8,AMACR,KCNE5,CADM1,SLAIN1,PITPNB,XRCC4,KCNT2,FMN2,ZNF74,PRDM2,PCDH15,FIP1L1,LINC00632,AMN1,KAT6A,RNF170" MicroRNA hsa-miR-133a-3p.2:TargetScan hsa-miR-133a-3p.2 TargetScan 3.53E-66 1.98E-62 1.39E-65 1.28E-64 141 487 "FAM43B,ADARB2,GALNT16,ADCY5,ADCY6,ESYT2,AP1B1,KCTD16,AK2,LRRC7,ABCD2,PITPNM2,ANK2,PPFIA2,CNTNAP1,PPFIA3,ARHGDIA,ARRB1,CDK13,PDE8B,DDX3Y,ATP2A2,BCL2L2,CDK5R1,JAZF1,NIPA1,MYRF,CACNA1B,CALM1,PTBP2,MAP7,RUNX1T1,CCNT1,FOXN3,KMT2C,DLGAP3,CLTA,FAM19A5,QKI,LETMD1,HS3ST5,CREB5,HAPLN1,ANKRD44,CSNK1G3,NCAN,PITPNM3,CCDC144A,ARHGAP24,MAML1,AIF1L,ELMO1,MTX3,DLG2,ANKRD46,FAM13A,EGFR,PAN3,ENPP6,CEP85L,EYA1,MED12L,FGF1,FGFR1,FOXG1,CELF1,DOT1L,NRG3,GABRB1,IQGAP2,CPLX2,PCDH17,C1QL1,RAB30,GPM6A,GRIA2,RFFL,GRM5,GRM7,PTPRT,DDX19B,MIER3,HLF,CELF5,NKD1,RBPJ,IL6ST,KCNA6,KCND3,ARHGAP12,MEIS1,MEIS2,DBNL,SAMD5,NCAM2,NELL2,NFIA,NFYA,PCSK5,PDE1C,GPR173,PFKFB3,PIK3C2A,KCTD15,CDIP1,PPP2R5E,PRKCB,PROX1,CNNM2,PTPRD,PTPRZ1,PRRT2,RFX3,KLHL11,EXD2,AP1AR,SCN2B,CASC3,HSPA4L,KIF21A,ARX,NTNG1,CNKSR2,BTBD3,RIMS1,HECW1,ANKRD28,ANKRD12,FAM208A,FBXW11,CUX2,PSD3,ARHGAP9,AP4E1,HHIP,GZF1,ELP5,DCBLD1,PITPNB,ELFN1,PHTF2" MicroRNA hsa-miR-133b:TargetScan hsa-miR-133b TargetScan 3.53E-66 1.98E-62 1.39E-65 1.28E-64 141 487 "FAM43B,ADARB2,GALNT16,ADCY5,ADCY6,ESYT2,AP1B1,KCTD16,AK2,LRRC7,ABCD2,PITPNM2,ANK2,PPFIA2,CNTNAP1,PPFIA3,ARHGDIA,ARRB1,CDK13,PDE8B,DDX3Y,ATP2A2,BCL2L2,CDK5R1,JAZF1,NIPA1,MYRF,CACNA1B,CALM1,PTBP2,MAP7,RUNX1T1,CCNT1,FOXN3,KMT2C,DLGAP3,CLTA,FAM19A5,QKI,LETMD1,HS3ST5,CREB5,HAPLN1,ANKRD44,CSNK1G3,NCAN,PITPNM3,CCDC144A,ARHGAP24,MAML1,AIF1L,ELMO1,MTX3,DLG2,ANKRD46,FAM13A,EGFR,PAN3,ENPP6,CEP85L,EYA1,MED12L,FGF1,FGFR1,FOXG1,CELF1,DOT1L,NRG3,GABRB1,IQGAP2,CPLX2,PCDH17,C1QL1,RAB30,GPM6A,GRIA2,RFFL,GRM5,GRM7,PTPRT,DDX19B,MIER3,HLF,CELF5,NKD1,RBPJ,IL6ST,KCNA6,KCND3,ARHGAP12,MEIS1,MEIS2,DBNL,SAMD5,NCAM2,NELL2,NFIA,NFYA,PCSK5,PDE1C,GPR173,PFKFB3,PIK3C2A,KCTD15,CDIP1,PPP2R5E,PRKCB,PROX1,CNNM2,PTPRD,PTPRZ1,PRRT2,RFX3,KLHL11,EXD2,AP1AR,SCN2B,CASC3,HSPA4L,KIF21A,ARX,NTNG1,CNKSR2,BTBD3,RIMS1,HECW1,ANKRD28,ANKRD12,FAM208A,FBXW11,CUX2,PSD3,ARHGAP9,AP4E1,HHIP,GZF1,ELP5,DCBLD1,PITPNB,ELFN1,PHTF2" MicroRNA hsa-miR-432:mirSVR_highEffct hsa-miR-432:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.84E-66 2.72E-62 1.90E-65 1.75E-64 187 852 "ABHD6,FAM43B,GALNT13,PWWP2A,MRTFA,PPFIA1,APAF1,GPAM,APOC1,SHTN1,ASPH,INSYN2B,EIF4G3,SLC2A11,N4BP2L1,DPY19L3,ADGRB3,DST,SYNJ2,MTMR2,THSD7A,KALRN,PTBP2,VSTM2A,PRC1,CCNH,USP2,TMEM257,DGKI,ARHGEF2,LGI1,RAB28,NRXN3,PPT2,KIAA1549L,AKAP6,COL4A5,CHD1L,SLC35F1,RNF14,FEZ2,SOCS5,PDE4DIP,ARHGEF4,CTNND1,USP6NL,DOCK4,FRMPD4,TOX,EARS2,PITPNC1,ELMSAN1,DNAJC6,HEPH,CEP170,RHOBTB1,GRIN3A,HS3ST2,DYNC1I1,CPEB2,DTNA,DNAJB6,DNM1L,CACNG7,OPTN,PHF20L1,GOLGA7,PLEKHA1,EMX2,TLR7,FABP7,FCGR1A,FCGR3A,KAT8,POLK,CAP2,SEMA4D,SGIP1,NOP56,C2orf88,ZMAT1,MEGF11,GABBR1,GABRA5,GAD1,GHR,PPARGC1A,TCERG1,GLS,LOXL3,NUDT21,EML4,PCLO,GRIA2,GRIA4,GRM7,ZNF496,MAEL,AGBL5,PLD5,IL6ST,SLC35G1,TTYH2,MAP2,SYT9,MDM4,ADAM22,ZNF92,NASP,NEUROD1,NRCAM,SNTG1,PCSK1,PCSK2,PDE1B,GNG2,ZNF655,PLP1,PILRA,PPARA,MINDY2,PRKCG,PKN2,MASP1,SAMD9,BDNF-AS,TMEM260,RAD51D,RASGRF1,DBX2,RFX3,RGS7,ARHGEF10L,RNASEL,ARMC5,PGBD4,FBXW7,ADAL,ATAT1,RXRG,ZNF331,LRRTM4,ST3GAL3,ABLIM3,DHX30,WDR47,RAB3GAP1,CCDC88A,IFT122,ANKRD36,SNRPN,SOX2,MCF2L2,RBM26,POGZ,SST,INKA2,ADHFE1,FGD4,NUDT10,SYN1,ADGRL3,DMXL2,PUM2,AHCYL2,CRB1,TJP1,ICAM5,TLL2,ERCC6L2,TMPO,TPM3,TRPC3,RFTN2,UBE3A,OSBP2,VGF,ZNF23,ANKS1B,FTSJ1,MEIS3,C12orf4,RGS7BP,DOCK8,CASC15,FAM219B,KLHDC1" MicroRNA hsa-miR-619:mirSVR_highEffct hsa-miR-619:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.09E-66 2.86E-62 1.99E-65 1.84E-64 181 801 "SYN3,ASIC2,ACTN2,NDRG3,NDRG2,KLHL32,ADCY6,SLC12A5,DPY19L2P4,ZNF608,HECW2,KCTD16,WDR35,ALCAM,OGT,MAP4K3,APC,MAGEE2,API5,CDC14B,MIER1,TMEM263,ARNTL,MARCH3,ASPH,DDX3Y,EIF4G3,ATP2B1,ZNF583,ATP6V1G2,BBS2,PROM1,ST3GAL5,RUNX1T1,KYAT1,CERS5,LRBA,MAGI1,PLEKHB1,CASC2,B4GALT6,LSMEM2,CLU,DNAJB5,TMEM184B,CNR1,FAM149A,AHCTF1,IGDCC3,FAM171B,ANKRD44,CLIP3,SNCAIP,CCDC144A,FRMPD4,GIT2,ARMCX4,FBXL5,ZC3H11A,ALKBH8,RABGAP1L,CPEB2,DRD1,RBM12,PHF20L1,EGFR,KMT5B,EGR3,CERCAM,MRNIP,TMEM35A,VPS13B,ZNF461,CACNG3,ZSCAN30,FOXG1,CAP2,EVL,STAU2,SARAF,GABRB1,GABRG2,ZMYND11,KIAA1841,TUBGCP4,ZNF276,CRCP,GLI2,GPD2,STON1,LPAR4,GRM1,PRDM5,GRM7,FAM19A2,RNFT2,TOX2,TLX1,RBPJ,IL6R,IL6ST,NCOA7,SYT9,MDM4,MSI1,ADAM22,SCG3,NCAM1,NCF2,NF1,DNHD1,GLIPR1L2,PCDH9,PCSK5,PDE3B,PDGFRA,CYTL1,A2ML1,CCSER2,POU3F2,RANBP3L,PRKACB,PRKCG,MAPK9,GRAMD1C,MASP1,MDGA2,ZSCAN32,PTPRB,PTPRD,ZNF615,TRIM68,SLC25A36,RPRD1A,CCDC82,RAVER2,ADAL,MAGI3,CTXN2,SLC1A3,SLC1A7,PEX26,KDM4D,SORCS3,SOX5,BDP1,KDM4C,LMO3,TAB2,ATP10B,ERBIN,ZSCAN29,NEK4,SULF2,ACSBG1,FGD4,NUDT10,FRYL,ITGB3BP,TNR,SYNPO2,RUSC1,CADM1,FAM155A,ZNF709,BCL2L13,BEST1,ETNPPL,ZNF154,LAMP5,PRTFDC1,LRP8,STMN4,PRDM10,RNF103,VPS35L,PCDH15,PARP11,C12orf4,GOPC,CASC15" MicroRNA hsa-miR-93-5p:Functional MTI Functional MTI miRTarbase 6.86E-66 3.85E-62 2.68E-65 2.47E-64 227 1220 "ADAR,FMNL2,ADD1,FZD9,AP2A2,SORCS2,ZNF578,KIF6,SEMA7A,USP28,APBB2,GPAM,CAPRIN2,ATP1B3,STX16,ATP2B1,MTMR9,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,FOXK1,MAP7,FMNL3,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,SLC4A7,ACBD5,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,FEZ2,SOCS5,DZIP3,UBXN2A,PPP6R2,ARHGAP32,DCAF8,KIAA0513,DAPK3,IP6K1,DNAL1,SPATA2,YTHDC1,ELMSAN1,DCTN1,PLEKHM1,FBXL5,CEP170,DDX46,SMG7,SACS,RABGAP1L,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,PLEKHA1,CERCAM,BSCL2,DCTN4,MTSS1L,ATP6V1G2-DDX39B,CDHR1,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,MED12L,GTF2IRD2,POLR1B,SUCO,FOXO3,ANKFY1,USP16,USP21,TPK1,MSANTD4,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,GNAS,PRUNE2,FUT10,RAPGEF4,NR3C1,CIT,MFSD2A,FICD,HAS2,HMGB1,ZIC5,IBA57,ITPKB,JAK1,KCNB1,KCND3,IPO5,CAMK2N2,SFXN5,ARHGAP12,GPR155,CHIC1,SCAMP5,AFF1,SESN3,MXI1,HNRNPM,NBL1,CNOT4,OCRL,GPR137C,PDE3B,PDPK1,PFKFB2,PFKP,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,SLC22A23,PXK,OCIAD1,RAB5B,CEP97,ATG16L1,OXR1,REV3L,RNF220,PBRM1,ZNF532,TMEM100,ATAT1,AP1AR,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,FAM102A,CHD9,SYBU,WDR37,RUFY2,BTBD7,CMTR2,FAM126B,SON,SP2,SP4,EMC1,SMOC1,STAC2,ANKRD12,CAMTA1,TAF6,WWC1,SMG6,TCF4,TCF7L2,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,DDHD1,ZFP91,PARD3,TPM4,ZNF384,RGMB,NR2C2,TSN,UBC,VLDLR,NSD2,ZIC2,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,UBE3B,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-888:PITA hsa-miR-888:PITA_TOP PITA 6.93E-66 3.90E-62 2.71E-65 2.50E-64 131 420 "ABR,CLK4,ADD3,USP31,ADRB2,ARHGAP20,GPRASP2,DPP10,LRCH2,GPAM,TMEM263,NUMB,DDX3Y,SLC4A4,SCAPER,KALRN,CDC42,MAGI1,QKI,SLC25A27,ZNF521,LRRC3B,SOCS5,DGKG,SCRN1,SPOCK3,G3BP2,FAM107B,DLG2,CALN1,DNAJB6,YAF2,CELSR3,MBNL2,ELAVL2,SRRM1,ETV1,DUSP27,EXTL2,TESK2,FOXG1,AFF2,OGA,DKK3,MTHFD2,DNER,ARFIP1,PCDH17,PPARGC1A,TOX3,TNRC6A,MSL3,GPR37,GRIA2,SOX21,MAP4K5,PACSIN2,ELOVL5,GABARAPL2,CELF5,LRRTM3,ITGAV,AQP11,MEF2C,MEIS1,MYCN,NDP,CNOT4,GPR137C,GNG2,TMOD2,XRN1,HMGCLL1,TRHDE,WBP1L,UHRF1BP1,ELOVL2,TMEM260,OXR1,KHDRBS2,MSANTD2,ZYG11B,REV3L,RGS4,ZNF532,RPE,RIMKLA,RTN1,ATXN7,SCN2B,FAM19A1,SCN8A,FNIP1,ELMOD1,SUPT20H,ITSN1,PPM1E,CHD9,FAM81A,EPN2,SEPHS1,SNAP25,TMCC1,ZCCHC24,NMNAT2,ARHGAP26,CLASP2,COLGALT2,SSTR2,SS18,PLCB1,SYN2,SYPL1,SYT4,ADGRL3,SATB2,WASHC4,CLASP1,CSMD1,TSC1,CADM1,UBE3A,ZNF711,LYPD6,REEP1,WNK1,PMEPA1,PRDM8,RNF103,GOPC,PHTF2" MicroRNA hsa-miR-145:PITA hsa-miR-145:PITA_TOP PITA 9.69E-66 5.44E-62 3.79E-65 3.49E-64 128 401 "CSMD3,FMNL2,ADD3,USP31,HECW2,RTL9,OSBPL1A,SEMA6A,SPOP,FAM135A,EPB41L5,PPFIA3,ARHGAP5,ZBTB10,ATP2B1,SYNJ1,BSN,THSD7A,FMNL3,CDH2,CFL2,QKI,MAP4K4,CABP1,TBPL1,CREB5,AKAP12,CTNND1,ARHGAP24,YTHDC1,ELMO1,MAGI2,ZC3H11A,ALKBH8,MTX3,WDR20,DLG4,HS3ST4,NR1D2,DPYSL2,RCAN1,DYRK1A,EFNA3,EFNB3,TENM1,GPHN,ERBB4,ACSL4,TOMM40L,FGFR3,AFF2,ST6GALNAC3,FUT9,AHCYL1,FAXC,GFRA1,GGT7,KDM2B,GPD2,GRB10,C1QL4,FAM19A2,BACH2,GABARAPL2,ZNF181,KCNA1,KCNA4,KCNK1,MEST,MYO5A,MYO6,NEXMIF,NRCAM,CDK14,XRN1,PPP3CA,PRPSAP2,TMEM255A,SH3TC2,REV3L,RGS7,SLC25A36,ZFHX4,CARF,CCDC25,RTKN,ATXN2,SCN2A,SCN3A,KIF21A,CPEB3,FNDC3A,NLGN1,SLC1A2,FAM81A,CPEB4,SLN,RIMS1,SON,SOX11,PEG10,ZNF423,POGZ,GANAB,ANKRD28,CAMSAP2,TBX15,TCF4,TRIM2,DOCK9,PSD3,CRTC1,FRYL,HEY1,TJP1,TP53BP1,TPM3,DOK6,UBTF,TBC1D15,PCDH20,ZNF138,TMEM178A,NAV3,SNX27,PAK5,RNF170,SLC4A10" MicroRNA hsa-miR-199a-5p:TargetScan hsa-miR-199a-5p TargetScan 1.32E-65 7.42E-62 5.16E-65 4.75E-64 131 422 "RALGAPA1,ACHE,ADD3,PLEKHH1,ARHGAP20,ANK3,MAP4K3,ALS2,MARK4,DDX3Y,ATP1A2,ATP2B2,BCL7A,DST,MTMR3,MYRF,BTRC,CA12,DDR1,CACNB2,CABP7,HIP1R,RUNX1T1,CDH2,CDH8,CHN2,CLCN3,CLTC,DNAJB5,CLOCK,PREPL,HAPLN1,NCOR1,SEC24C,FAM169A,KIAA0040,RASSF2,IST1,MYEF2,KIAA0753,KLHL3,SACS,FAM107B,DYRK1A,ABCC5,E2F6,PLXNC1,RGS17,PAN3,EPB41L1,RAB9B,ERBB4,CEP85L,REEP2,DLC1,FER,KIAA1109,PCYOX1,NSG1,FUT9,NCKAP1,GCNT2,PCDH17,CSDC2,PPARGC1A,KIAA1958,GPD2,CECR2,GRB10,RFFL,GRIK3,PRDM5,HAS2,ARHGAP19,KLF12,MIER3,HLF,METTL21A,KCND3,KLHL23,KIT,PAXBP1,ARHGAP12,MAP2,AQP11,MATN2,MGAT3,PPM1L,MN1,GIT1,MYO5A,NBL1,NFYA,P2RX7,PDE4D,PLXNB1,PMP22,FSD1,PPM1B,PKN2,MAPK4,MAPK8,FIGN,RFX3,RGS10,PBRM1,RORB,CLIP1,ATXN7,ASRGL1,PPP1R9A,NTNG1,BTBD3,RIMS1,MBD5,FAM126B,EPB41L3,LARP4,GANAB,ARHGEF12,ATP13A2,HHIP,CBX5,R3HDM1,RGMB,RGMA,MARCH8,PHTF2,ADAMTSL3,FXR1,JPH3" MicroRNA hsa-miR-199b-5p:TargetScan hsa-miR-199b-5p TargetScan 1.32E-65 7.42E-62 5.16E-65 4.75E-64 131 422 "RALGAPA1,ACHE,ADD3,PLEKHH1,ARHGAP20,ANK3,MAP4K3,ALS2,MARK4,DDX3Y,ATP1A2,ATP2B2,BCL7A,DST,MTMR3,MYRF,BTRC,CA12,DDR1,CACNB2,CABP7,HIP1R,RUNX1T1,CDH2,CDH8,CHN2,CLCN3,CLTC,DNAJB5,CLOCK,PREPL,HAPLN1,NCOR1,SEC24C,FAM169A,KIAA0040,RASSF2,IST1,MYEF2,KIAA0753,KLHL3,SACS,FAM107B,DYRK1A,ABCC5,E2F6,PLXNC1,RGS17,PAN3,EPB41L1,RAB9B,ERBB4,CEP85L,REEP2,DLC1,FER,KIAA1109,PCYOX1,NSG1,FUT9,NCKAP1,GCNT2,PCDH17,CSDC2,PPARGC1A,KIAA1958,GPD2,CECR2,GRB10,RFFL,GRIK3,PRDM5,HAS2,ARHGAP19,KLF12,MIER3,HLF,METTL21A,KCND3,KLHL23,KIT,PAXBP1,ARHGAP12,MAP2,AQP11,MATN2,MGAT3,PPM1L,MN1,GIT1,MYO5A,NBL1,NFYA,P2RX7,PDE4D,PLXNB1,PMP22,FSD1,PPM1B,PKN2,MAPK4,MAPK8,FIGN,RFX3,RGS10,PBRM1,RORB,CLIP1,ATXN7,ASRGL1,PPP1R9A,NTNG1,BTBD3,RIMS1,MBD5,FAM126B,EPB41L3,LARP4,GANAB,ARHGEF12,ATP13A2,HHIP,CBX5,R3HDM1,RGMB,RGMA,MARCH8,PHTF2,ADAMTSL3,FXR1,JPH3" MicroRNA hsa-miR-635:mirSVR_highEffct hsa-miR-635:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-65 7.90E-62 5.49E-65 5.05E-64 163 658 "ABCF1,RBM10,KDM5D,NDRG3,KLHL32,GALNT13,ADD2,SLC12A5,PTCHD1,AP2A2,HECW2,CC2D2A,HFM1,TAOK1,LCORL,PKP4,ALS2,SHTN1,PCDHGB4,TTLL9,BACH1,DCAF5,ARHGEF25,LDB2,P2RX6,LGI1,MS4A7,TJP2,QKI,CNR1,AKAP7,SUMF2,ABI3BP,RIPOR2,KIAA0513,LONRF1,DAPK1,YTHDC1,C8orf34,CEP170,DLX1,DMD,DNM1,DYNC1I1,DPP6,TOM1,AASDH,EDNRB,SIDT2,APH1A,EPB41L2,SRRM1,RRAGB,GMPR2,F5,FOXG1,SLC37A3,SMC2,APOPT1,CAMKK2,ATP2C1,ST6GALNAC3,BRSK1,ZMAT1,MEGF11,GABRA2,GABRB1,GAD1,INPP5K,LRRC37A6P,GATM,CBX1,DCLK2,GRIA4,NR3C1,LINC00839,SOX21,ARHGAP36,HMGCL,IL11RA,JAK1,KCNJ16,HECTD2,LDLRAD3,MDM4,MOBP,MSI1,MTR,NF1,SLC11A2,OLR1,PAH,PCDHGC3,PCDH9,CDK18,DUSP26,GDAP1L1,HMGCLL1,PMP2,DRAM2,MED1,PPP3CA,PROX1,SNRK,PSMD13,STK32A,PTPRE,FAM120C,RAD51D,ZDHHC14,RIT2,RNASEL,ZFHX4,EXD2,HSD11B1L,RTN1,ATXN7,FAM19A1,SLC30A10,SLC8A3,ARHGEF40,CABCOCO1,BDP1,CAND2,IQSEC2,SRPK2,NKAIN2,SSPO,JMJD6,ABCC8,TACC1,ANO4,WASHC4,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,PCDHB10,PRMT8,RUNDC3B,MTCH1,VLDLR,PCDH20,ZBTB14,AGMO,LYPD6,ZNF138,ZSCAN26,MAP3K12,LRP8,SEMA3B,MPPE1,CASC15,JMJD1C" MicroRNA hsa-miR-3118:mirSVR_highEffct hsa-miR-3118:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.73E-65 9.69E-62 6.72E-65 6.19E-64 183 824 "KCNH8,SORCS1,INTS2,KIAA1324,WDR35,AMPH,SUGT1P4-STRA6LP-CCDC180,EPB41L5,CACHD1,CAPRIN2,ASPH,ZBTB10,NCOA1,NUMB,ATP2A2,ATP6V0A1,BACH1,MPDZ,MTMR2,CACNA1D,CARS,RUNX1T1,ZNF501,SLC16A4,P2RX6,MAGI1,CHN2,JAM2,TPP1,FAM19A5,MAP4K4,ARHGEF6,MFSD4A,CPS1,FAM171B,ANKRD44,SNCAIP,ARHGEF10,KIAA0040,RIMS2,ZSCAN23,DOCK4,ARMCX2,CEP170,AK5,DMD,DNAH9,PDCD6IP,DSCAM,GNE,EDN1,EDNRA,ATL1,EGFR,KMT5B,GOLGA7,EIF1,VPS13B,TMEM74,EXTL2,TAOK3,KIAA1109,ZNF605,GABBR1,CAB39,ILDR2,BRPF3,ERAP1,MSTN,PPARGC1A,GLUL,PCDH11X,CBX1,GNAL,GNAO1,MCHR1,EML4,CECR2,GRIK2,PSIP1,GYG1,HAS2,ARHGAP36,MIER3,HNMT,HSP90AA1,KCNC1,KCNK2,KCNMA1,KPNA5,STMN1,NCOA7,MAOB,MAT2A,MBNL1,LRP1B,MMP16,NFE2L2,NRCAM,NRDC,NTRK2,LOC100128398,GPR137C,PCDH9,CDK14,NALCN,PIK3C2A,A2ML1,XRN1,PLCB2,PLP1,HMGCLL1,CEP41,PRKCG,HYDIN,BCAS3,PTPRB,SUSD4,CRTAC1,SEC61A2,NUDT11,ROBO2,ELP2,PCMTD2,RPL15,ATP8B4,ADAL,WLS,ZNF354C,SCN2A,TNFRSF19,ITSN1,MAGI3,CCDC92,ST3GAL3,SLA,RAB3GAP1,SLC14A1,GKAP1,SMARCE1,RIMS1,ZNF415,SNRPN,SP4,SPTAN1,KIF1B,NPAS3,NFASC,CLSTN2,KANK1,AJAP1,ACSBG1,VPS13A,FBXW11,ANO4,ZFPM2,TMEM9,KAT6B,ZMYND8,PPIL6,SSBP2,RFTN2,ZKSCAN5,TMEFF2,SGK3,CADM1,SLAIN1,BEST1,WIPF1,ZNF711,ZNF28,TRIM9,FMN2,NDRG4,MKRN3,FSTL5,SLC30A4,MFF,LRP8,ADAMTS9,TRAM2-AS1,KLHDC1,SENP7" MicroRNA hsa-miR-362-3p:mirSVR_highEffct hsa-miR-362-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.55E-65 1.43E-61 9.93E-65 9.15E-64 174 750 "ADD2,AP2A2,HACE1,ADGRF5,MRTFA,PHF12,BCAS1,MIER1,RGS20,ASPH,EIF4G3,ATP1B3,BCL7A,DCAF5,BMPR1B,BTRC,CACNA1D,PTBP2,TRIM41,SPAG9,ARHGEF25,KRIT1,ZMYM4,SOCS6,PLAA,CLU,CLTB,ARHGEF6,COL9A3,IGDCC3,RBM39,CRMP1,RNF14,ABCG1,CSNK1G3,PDE4DIP,EDRF1,LONRF1,DAPK1,COPS7A,ARNT2,GNE,GOLT1B,EDNRA,SYT15,PHF20L1,SUGP2,EIF4G1,ELAVL2,CALCRL,EPHB1,TOMM40L,FGF12,FGF14,ACTL6B,SLC37A3,JKAMP,NBEA,POMT1,ST6GALNAC3,SARAF,DKK3,RAPGEF6,DISC1,WASHC2A,USP19,MALT1,GLYR1,TNRC6A,MSL3,PCDH11X,KDM2B,MAP7D2,DCLK2,NR3C1,BTN2A1,RNFT2,MAP4K5,MAEL,TNFAIP8L3,HNF4G,SMAP1,IL6ST,OLFM3,KCNC1,KCNMA1,GPR155,MARK1,POC1B,RTL5,NDUFA5,NF1,NPY,NOVA1,P2RX7,PCSK5,PDE3A,PDE4D,PDGFRA,PDYN,OLA1,ZNF655,PLIN1,PLP1,PRKACB,CEP41,SLC26A11,GON4L,QRICH1,PTPRG,FAM184A,ZNF493,OXR1,ERI2,ZDHHC4,RGS10,ARHGEF10L,ZFHX4,CCDC102B,RPE,RPL15,MIR124-2HG,LRFN5,LRRTM4,SCN8A,FBXO11,NUBPL,PAAF1,SEPHS1,TET1,ZNF667,CMTR2,LARP4,ELOVL4,FGD4,PRRC2C,SYN2,SYT4,TACC1,TCEA1,ZEB1,DOCK9,PCDHB10,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TIAM1,HEY1,ERCC6L2,RGMB,TRPC1,UBE2H,PLEKHH2,CLDND1,PCDH20,ZBTB14,ZIC3,SCG2,CIAPIN1,NAV3,RGS7BP,UBE3B,HNRNPA3,PHTF2,NHSL1,NETO2,CBLN2,FAM198A" MicroRNA hsa-miR-5011-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-65 1.57E-61 1.09E-64 1.00E-63 162 653 "ABCF1,ADD2,GRAMD1B,NLGN4X,ZNF608,HACE1,TAOK1,PCDH10,APP,MARCH3,BACH1,FUBP1,CA8,CA12,THSD7A,RUNX1T1,TBRG4,CFL2,B4GALT6,SLC24A2,C4orf33,QKI,SLC25A27,TBPL1,ACBD5,ANKRD44,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,DBT,PITPNC1,SPATA2,SV2B,G3BP2,CDON,CPEB2,YAF2,MBNL2,ABI2,PLEKHA1,CERCAM,TUBD1,RCAN2,EPHA5,ACSL4,FER,POLR1B,TMEM164,TRMO,ZBED3,NPTN,CELF1,MPP6,GABRG1,GCK,MMADHC,PPARGC1A,TCERG1,COPS8,KCNMB4,TPPP,GRID1,GRIK3,BVES,INSYN1,BACH2,USP51,NEGR1,HSF2,IGF1,IGFBP1,ZIC5,DOCK7,SCIN,IL6ST,KCNB1,CLVS2,KCNJ3,KLHL23,KCNK1,KCNN3,L1CAM,FGFBP3,SMAD9,MMP16,CCDC80,MYBPC1,NEXMIF,NCAM2,NELL2,NFIA,NTRK3,OPCML,PIK3R1,XRN1,PLP1,PURG,LRP12,PRRX1,PPP1R1A,PPP2R5C,PPP2R5E,PROX1,SNRK,PTPRD,RAB5B,CEP97,SH3TC2,PRIMA1,RIC8B,CARF,FBXW7,ACER3,AP1AR,CSRNP3,FAM19A1,ZFP30,LRRC55,SLC6A8,SLC8A1,RAB3GAP1,SLC12A2,FAM126B,WDTC1,SOX5,ZHX3,ERC1,STAU1,PRRC2C,SYP,TMEM178B,TRIM2,AHCYL2,SIK3,ZMAT3,HHIP,BEX4,CSMD1,DOK6,RGMB,NR2C2,CADM1,PITPNB,OSBP2,MEAF6,KCNK12,ZBTB16,SMARCAD1,SLC30A4,PMEPA1,MAP3K12,ZXDA,LRP8,EVI5,STOX2,ADAMTS9,FAM182B,KAT6A,SSPN" MicroRNA hsa-miR-6867-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-65 1.69E-61 1.17E-64 1.08E-63 136 459 "PTCHD1,NLGN4X,TAOK1,CARNS1,MARCH4,PCDH10,BCAS1,ARRB1,MARCH3,THSD7A,CALM1,RUNX1T1,CCNT1,CFL2,FOXN3,RAB3C,KIAA1549L,NRXN1,TMEM184B,IGLON5,CREB5,AKAP12,SUSD5,NCAN,PPP1R16B,ST18,PYGO1,DCAF8,DBT,DNAJC6,JAKMIP2,TMEM130,SV2B,CHRDL1,DMD,CDON,DMTF1,GNE,ABI2,EN2,EPHA5,KATNAL1,TBC1D16,FGF14,UBE2E3,FOXG1,EFCAB2,TRMO,C15orf41,FAXC,MMADHC,GFRA1,GLI2,GLYR1,PCDH11X,CBX1,DIPK1C,IL1RAPL1,BVES,SLC2A6,SYNPO,ZDHHC15,IGF1,NKD1,DOCK7,IL6ST,KCNB1,KCNJ3,KLHL23,KCNN3,KCNQ3,SMAD9,MAP2,CHIC1,MITF,HS6ST3,MYO5A,NEXMIF,NELL2,NOS1,OLR1,OXTR,KCNK10,GPR173,NLGN3,ZNF655,CCSER2,PLP1,PSAT1,SDK2,SPATA6,PRKCB,MAPK10,PROX1,SH3TC2,RGS4,TTLL7,PGBD4,KIAA0895L,KCNIP3,SATB1,CSRNP3,SLITRK3,RPH3A,PEX26,SON,SOX5,ZHX3,NMNAT2,KIF1B,NCDN,ARHGEF9,PLCB1,ASTN2,MGRN1,ATMIN,ZEB1,TRIM2,TMEM151B,HHIP,THRA,DDHD1,NR2E1,TNR,DOK6,LRTM2,TUB,VSNL1,PORCN,KCNK12,ELFN1,DPYSL5,STOX2,KAT6A,ZDHHC20,SSPN" MicroRNA hsa-miR-3180-3p:mirSVR_lowEffct hsa-miR-3180-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.15E-65 2.33E-61 1.61E-64 1.49E-63 159 631 "DPF1,CPNE2,FAM43B,GPRIN1,RNF157,PWWP2A,BEGAIN,AMH,EP400,DGKZ,CDK10,MADD,SPTBN4,ARHGDIA,ARHGDIG,ATP1A3,KSR1,CDK5R2,CAMK2G,TRIM41,BRSK2,USP2,ARHGEF1,ENTPD2,EVI5L,NUMBL,NRXN3,CCDC151,FAM149A,ZNF385A,ANKRD44,NCOR2,GDA,PLCH2,SIRPA,RUSC2,SMG7,AK5,DLG4,HS3ST2,DTNB,ANKRD46,EEF1A2,CACNG7,EFNA3,CELSR3,EIF1,OLIG2,MTSS1L,EPHB1,ANKRD13B,SRRM1,SPEG,RTN3,EXTL1,REEP2,PTK2B,KAT8,BAIAP2,PRKAG2,AGAP2,SEMA6C,ERGIC3,ZNF274,ALDH1L1,TUBA8,ZNF276,ATF7,STMN2,GRB10,C1QL4,GRIN1,PTPN5,LINGO1,MUM1,IGSF21,PACSIN2,HPSE2,HMGCL,HPCA,IDH3A,LRRC25,KNDC1,IL11RA,KLRC3,L1CAM,LRRC4B,PPM1L,XRRA1,MSI1,RTL5,FXYD7,FXYD6,NEUROD2,SLCO1C1,NRGN,OGG1,ZDHHC22,PBX1,PCSK5,PDE4A,GPR173,PFKFB3,NLGN3,CCSER2,PLEC,PILRA,POLR2F,CNNM2,SUSD4,PRRT2,KCTD17,ARHGEF10L,SYNDIG1,ATAT1,YJEFN3,STX1B,FOXRED2,ITSN1,ARX,MYO18A,NTNG1,HKDC1,FAM81A,SLC6A9,SLC12A4,KIF13A,SNRPN,SOX10,IQSEC2,TSPYL2,MCF2L2,C11orf87,NCDN,STX1A,SYN1,SYN2,EXOC7,PDLIM2,TBX15,TCF4,NEU4,NAT16,TNS2,TMEM121,FBXL16,TNNT1,PIK3R5,RASD2,NPL,C9orf85,SMUG1,CLEC2L,ZIC2,FMN2,GDPD5,PRDM8,TMEM178A,TMEM163" MicroRNA hsa-miR-490-5p:mirSVR_highEffct hsa-miR-490-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.90E-65 2.75E-61 1.91E-64 1.75E-63 170 720 "SLC25A25,TAOK1,ARHGAP20,MARCH4,FAM135A,OGT,CDC42BPA,ANK2,PPFIA1,PARG,APBA2,USP37,SHTN1,CADPS,PDE8B,RNF182,ADAM23,BACH1,ARHGEF7,CACNA1D,CACNA1E,TMEM257,CDH2,DCLK1,MAGI1,CASC2,NRXN1,FAM19A5,DNAJB5,MAP4K4,NIPBL,FHL5,SLC25A27,SLC4A8,RCHY1,NRSN1,RIPOR2,ARHGAP24,TOX,PHF19,LIN54,ARMCX4,HP1BP3,CHRDL1,DMD,DNAH9,DTNA,GOLT1B,E2F6,EDN1,STARD3NL,TUBD1,KCNMB2,GPHN,SRRM1,F8,SCML2,FGF14,PRKAG2,FLT1,TRMO,GABBR1,TUBGCP4,MSTN,ADAM28,MALT1,TXNL4A,TOX3,FERMT2,LILRA1,GRIA1,GRIA2,GRIN1,PRDM5,HPS5,ZHX1,FRMD5,MIER3,HMGB1,IGFBPL1,HTR5A,ZIC5,USP54,ZNF385B,SLC35G1,STXBP5,PAXBP1,MAT2A,MEIS2,MTTP,NF1,LRIT2,LOC100128398,PDE3B,PDGFRA,PFKFB2,SNX10,PLP1,MTRF1L,PMP2,SPATA6,EPB41L4B,HYDIN,SAMD9,VPS13C,WBP1L,SIDT1,TMEM260,OCIAD1,PTPRD,RAB5B,RALGDS,RAP1GDS1,RGR,RIC8B,CARF,ROBO1,ACER3,ATAT1,WLS,LRFN5,ASRGL1,ZFP30,SH3GL3,FERMT1,NTNG1,FNDC3A,WDR37,SLC6A1,CCDC88A,SLCO1A2,TET1,ANKRD36,UNC80,SOX2,MYCBP2,UNC5B,ZNF423,CLASP2,ERBIN,STAU1,SYT11,SATB2,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TF,C5orf64,RGMB,PRMT8,TRPS1,CA14,TSC1,RPL7L1,BEST1,SLC13A3,ZNF177,SMARCAD1,EMSY,RGS7BP,UBE3B,NLRP3,RNF170,FRMD6,SLC4A10" MicroRNA hsa-miR-3150:mirSVR_highEffct hsa-miR-3150:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-65 2.97E-61 2.05E-64 1.89E-63 182 821 "CPNE2,SERPINA3,CLK4,GPRIN1,ADCY2,CCDC85A,GRAMD1B,ADORA3,NLGN4X,SNX32,CC2D2A,CARNS1,LTBP4,FGD2,BCAS1,API5,ARRB1,CDK13,DACT3,MPDZ,SEC11C,BCL2L2,KALRN,SLC25A14,SYT6,CAST,ARHGAP33,TIGD7,CFL2,NDST3,PPT2,ABCG2,AKAP6,BTF3L4,COL9A2,COL11A2,CPS1,CLIP3,MICAL2,VCAN,GREB1,ZNF337,ACY3,SPOCK2,MAGI2,SMG7,SPOCK3,SV2A,TMCC2,NYAP1,CPEB2,DOCK2,DTNB,DYRK1A,SEZ6L2,EDN1,OPTN,APH1A,SORBS3,ENO2,RABEPK,SRRM1,ANKMY1,SIRPB1,PTK2B,TESK2,PPP1R1B,ACTL6B,UBE2E3,IP6K2,NELFCD,ARFGAP2,NSG2,GAD1,B4GALNT1,ARPP21,MTHFD2,INPP5K,ALDH1L1,TXNL4A,HPGDS,GLDC,LOXL3,GPD2,PRLHR,PCLO,GRIK1,CLASRP,PADI2,ARHGAP36,HPSE2,HTR5A,IDH3B,DISP2,NME9,SLC35G1,METTL21A,KCNC1,CREG2,KIF5A,KLRC2,CAMK2N2,HECTD2,NCOA7,MARK1,MBD1,MEIS2,MEST,MN1,MT3,LAYN,MYO7A,MYO9A,NNAT,NOVA1,OGG1,OPHN1,CLDN11,CDK18,PDE4D,BEST3,PFKFB2,ZNF655,FAM216A,C19orf57,POU3F2,PPP2R2B,PRKACB,KLK6,MDGA2,PTPRH,PEX5,RAB5B,RAP1GDS1,RASGRF1,BSDC1,SEC61A2,RPRD1A,SUGCT,C12orf49,GSTCD,NEK11,TRIM46,TRA2B,COPZ1,ITSN1,NTNG1,SLC1A7,FAM214B,SIRT2,SMARCC2,SORCS3,SMARCD3,RIMS1,SNCB,FNBP1,C11orf87,ATP10B,NCDN,STAU1,FAM168A,SUPT5H,UNC5D,TPCN2,PCDHB4,ARHGAP9,FRYL,CCDC173,ZMAT3,TIMP4,ZNF384,KCNE5,UCHL1,OSBP2,SF1,PLPPR5,SLC17A7,WNK3,UBE3B,PHTF2,PIANP,NETO1" MicroRNA hsa-miR-1178:mirSVR_highEffct hsa-miR-1178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.30E-65 2.97E-61 2.05E-64 1.89E-63 168 704 "ASPHD1,KDM5D,ADD3,PTCHD1,RTL9,TXNDC16,ABCD2,ANK3,CCDC146,PKP4,PARG,UPRT,GPAM,API5,ZSCAN18,EIF4G3,ADAM23,RGS9,NRP2,SYNJ1,SGCE,TRIM41,SPAG9,DGKI,LRBA,CACNA2D2,SRSF11,RAB33A,TMEM184B,ARMC8,SLC4A8,ACBD5,HS3ST5,ZNF385A,RNF14,SOCS5,PHF14,NOS1AP,DOCK4,ZFYVE16,PABPC5,ZEB2,ZBTB24,MAGI2,G3BP2,EXOG,CPEB2,EDNRA,EGR3,COQ7,EPS8,NCALD,NRN1,MEX3B,NELFCD,TACC2,PDLIM5,NPTN,AP4B1,GABRA2,GABRA5,CHL1,GABRB1,ARPP21,IQGAP2,DISC1,MSTN,HPGDS,GLRB,GLS,MSL3,PCDH11X,CBX1,KDM2B,GNAS,GPM6A,STON1,MCHR1,GRIA2,GRIA4,GRIN1,MFSD2A,LINC01551,PSIP1,GYG1,GABARAPL2,LRRCC1,LRRTM3,LAMP2,INSYN2,MARK1,MAT2A,TM6SF1,MEIS1,MIA2,POC1B,MITF,MYO9A,NEK1,NF1,PBX1,GPR85,NALCN,A2ML1,HMGCLL1,SH3KBP1,POU3F2,PPP3CB,PROX1,CNTLN,ENOX1,SLC6A15,ZYG11B,ZMAT4,RFX4,RGS12,RIC8B,CARF,PCMTD2,CCDC102B,MRAP2,MEG3,ATAT1,DGLUCY,LRRTM4,FERMT1,NTNG1,SLC1A3,SEPHS1,BTBD7,SNCA,SON,WDTC1,HECW1,KDM4C,ZC3H13,SSTR2,PRRC2C,TBX15,EHBP1,TCF7,PCDHB10,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,LEFTY2,HHIP,TMPO,RIMBP2,TPM3,SYNPO2,PRMT8,STXBP4,ZMYND8,ZIC3,PMEPA1,RGMA,ST7,PAK5,HNRNPA3,MSRB3,SLC4A10,SENP7" MicroRNA hsa-miR-4299:mirSVR_highEffct hsa-miR-4299:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.81E-65 3.26E-61 2.25E-64 2.08E-63 171 729 "ABCF1,SLC24A4,LRRC7,ARHGAP20,BIN1,OGT,PKP4,MIER1,SFMBT2,ATP2B1,B3GALT2,SEC11C,KSR1,JAZF1,BAIAP3,CCK,KRIT1,INA,ENTPD6,MAGI1,TPP1,IQCK,FAM149A,SLC4A8,MFSD4A,ZNF385A,GDA,CLIP3,SNCAIP,SEC24C,CSNK1G3,ATRNL1,PLCH2,SOCS5,CFAP61,RIMS2,CX3CR1,ARHGAP24,AIF1L,GIT2,ARMCX2,DMD,KLHL5,YAF2,EFNB3,MRO,KMT5B,GOLGA7,ASB3,ELAVL2,STARD3NL,EPB41,RCAN2,GPHN,CLVS1,FAM198B,ZNF461,SCML2,FGF12,FGF14,FOLH1,NBEA,HHIPL1,ABLIM2,PHYHIPL,DISC1,NEU3,ADAM28,PPARGC1A,KIRREL3,GLI2,RAB30,ZNF638,FERMT2,TDRKH,GPR19,LPAR4,CLASRP,LINC01551,IRAK3,HPSE2,HNMT,HNRNPK,JAK1,KCNK1,KIF5A,KIF5C,HECTD2,PIK3AP1,MAOB,XRRA1,COL28A1,MSR1,NRBP2,SCG3,PABPC1L2A,NDUFA5,NTRK2,NUCB2,IGSF11,PDE4D,GPR85,GNG2,CDK14,HERC2P3,CAMKV,FTO,SLC22A23,PTHLH,TMEM260,PTPRG,NKAIN1,TTC13,ZNF615,RAD51D,ZNF493,MSANTD2,ZYG11B,RFX2,RGS10,RERGL,RORB,GLDN,WLS,CLIP1,SAFB,ATXN2,FOXRED1,ITSN1,ASAP3,SHC4,NLGN1,RAB3GAP1,SLC8A3,SLC11A1,TMEM132D,TET1,TMCC1,BDP1,UHRF1BP1L,PBLD,ZSCAN29,NSFL1C,MCF2L,UNC5D,ADGRL3,ANO4,WDR7,SYNE1,RNF216P1,SPX,LEFTY2,SLC44A1,TPD52,TPM2,AMACR,CLHC1,SLAIN1,CCDC136,ZNF781,KLC2,GUSBP1,CFAP298,ZNF540,PLPP4,ZSCAN26,PHTF2,CASC15,IFT88,NETO1,PRRT4" MicroRNA hsa-miR-378c:mirSVR_highEffct hsa-miR-378c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.72E-65 4.34E-61 2.99E-64 2.75E-63 202 1000 "SORCS1,SLC44A5,CC2D2A,ARHGAP20,FAM135A,OGT,ALS2,DDO,TNRC6C,TMEM263,PLA2G4C,CAPRIN2,EIF4G3,NOL4,BCL2L2,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,CDC27,CDH8,LGI1,TIGD7,COPB2,SYNPR,PPT2,KIAA1549L,CLCN4,DNAJB5,C4orf33,SRP14-AS1,LY86,RAB26,AKAP7,AHCTF1,TOGARAM2,ZFP28,CDC42BPB,CREM,RNF14,CS,ARHGEF10,PHF14,USP6NL,CCDC144A,DOCK4,RIPOR2,DCAF8,FRMPD4,DCC,DNAJC6,DDX46,G3BP2,GRIN3A,HS3ST4,DOCK2,DSCAM,DYRK1A,DNM1L,EBF1,WDPCP,HIPK3,RBM12,SH3GLB1,CELSR3,MBNL2,KMT5B,ENPP6,SPEG,FAM198B,FABP7,FCGR1A,CEP78,FCGR3A,KIAA1109,FGF12,TMEM164,ATP5PD,FOXG1,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRB1,GABRG2,ERAP1,C15orf41,DISC1,GLS,GNAS,GPT2,TDRKH,GRIA4,GRIN2C,ZNF496,TMEM25,GSTM5,SLC2A6,ZHX1,MAN1B1,HMGB1,SMAP1,IDH3B,MYLK2,IL6ST,IL11RA,KCNJ10,KIF2A,KIF5C,MAP6,MARK1,MEST,CD200,CTNNA3,LYRM9,NAP1L3,NCAM2,NDP,NEK1,NEUROD1,NF1,NFE2L2,NUCB2,IGSF11,CHAMP1,LOC100128398,SNTG1,PAK3,ETFRF1,CAMKV,C11orf49,TRHDE,PPP3CA,PRKACB,RAB39A,PRPSAP2,DCHS2,SIDT1,SNRK,PTPRD,USP47,FIGN,RFX4,RGS4,CARF,ELP2,UEVLD,FBXW7,BAALC,KCNIP2,KCNIP1,RXRG,SEMA6D,RAB3GAP1,ATF7IP,SORCS3,MBD5,IQSEC2,EPB41L3,NXT2,NEK4,DIP2A,ACSBG1,PLCB1,COBL,SYT4,TACR1,CAMTA1,AGTPBP1,VWA3A,DMXL2,FRYL,ZFPM2,AP4E1,ZNF106,GZF1,TMOD1,SEZ6L,PPIL6,BEST1,GUSBP1,TRIM9,PLPP4,SLC26A10,CELF4,EML6,ZNF189,UPF3A,CADM2,PRTFDC1,FIP1L1,PDSS2,EPM2A,ST7,CAMK1G,ZNF248" MicroRNA hsa-miR-99b*:mirSVR_lowEffct hsa-miR-99b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.33E-65 4.68E-61 3.22E-64 2.97E-63 154 595 "CLK4,NCKAP5,GRAMD1B,PWWP2A,FAHD2CP,CC2D2A,SRPX,CARNS1,OGT,SUGT1P4-STRA6LP-CCDC180,API5,CDK10,TMEFF1,PDE8B,ZBTB10,BARD1,BCHE,RGS9,SYNJ2,RAB29,KALRN,TRIM41,L3MBTL4,ASIC3,JAM2,LHX2,WHRN,COL9A1,HS3ST5,CSNK1E,OSBPL3,SOCS5,RASGEF1C,PUM1,CYBB,KCTD8,ZEB2,DNM1L,EDN3,HIPK3,SRRM1,CLVS1,TAOK3,PRKAG2,SORBS1,APOPT1,STAMBP,CAMKK2,STAU2,STAG2,CHL1,TRAF3IP2,HBS1L,FAM120B,GALR1,CPLX1,GGT7,GLYR1,GLUL,ZNF638,GRID1,GRM7,CLASRP,HLF,HMGB1,AGBL5,HNMT,HP,HPR,LINC00667,IGF1,IL6R,ZNF385B,KCNB1,KCNJ10,KCNN3,KIT,C2orf80,LOC100128239,MSR1,CTNNA3,LYRM9,FXYD7,NCAM2,NELL2,NF1,NOVA1,NUCB2,OMG,PCMT1,ENPP2,PDYN,HERC2P3,JAKMIP1,RC3H2,EPB41L4B,FA2H,MAPK4,VPS13C,CNTLN,TMEM260,TRIM68,PRRT2,FIGN,SEC61A2,RPRD1A,GLDN,MAP6D1,SCP2,HSPA4L,SCG5,ITSN1,ARX,CPEB3,CHD9,FNDC3A,ZNF365,EPN2,RUFY2,PKNOX2,SNRPN,USP33,BEX1,KIF1B,NFASC,PBLD,ITPRID2,THSD1,PRRC2C,TAL1,VWC2,TPCN2,TRIM2,SYNE1,DOCK9,CCDC173,R3HDM1,SSBP2,MEAF6,CCDC14,WIPF1,CLIP2,LYPD6,CSDE1,VPS35L,SEMA3B,PPP1R3F,KCNAB1,KAT6A,PHTF2,ZNF248,SOCS4,GAN,JPH3" MicroRNA hsa-miR-1282:mirSVR_lowEffct hsa-miR-1282:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.75E-65 4.91E-61 3.39E-64 3.12E-63 166 690 "RALGAPA1,KCNH8,SYN3,GALNT13,CC2D2A,DPP10,ANK1,ANK3,MAP4K3,PPFIA2,SUGT1P4-STRA6LP-CCDC180,ALS2,ARNTL,MARK4,DDX3Y,EIF4G3,BCL7A,BMP7,FUBP1,BTK,CA8,CANX,VSTM2A,SPAG9,RUNX1T1,CCNH,LGI1,LOC730101,NOG,ZBED5,CNOT8,RAB33A,NRXN3,NIPBL,FHL5,FAM149A,AKAP6,ACBD5,ZNF521,RGS6,ST18,DCAF4,TOX,ZEB2,HEPH,DMD,DTNA,ECM2,DNAJB6,FAM13A,PHF20L1,SUGP2,KCNMB2,DENND4A,GTF2IRD2,FGF12,IP6K2,EFCAB2,PDLIM5,NPTN,ATP2C1,NSG2,STAU2,ADGRA1,GABRA1,GABRA5,GAD2,GAP43,SULT1C4,GFRA1,ZNF276,GLI2,RAB30,GNAS,PRUNE2,GPR37,GRIA2,GRIK4,ADAMTS8,GRM8,PSIP1,FAM107A,MAP4K5,ELOVL5,IGFBPL1,CPT1C,CELF5,LRRCC1,IGSF1,SCIN,KCNA4,KCNB1,KCNN3,STMN1,NCOA7,ASPRV1,MAP2,MBD1,MITF,MKLN1,ZNF680,CCDC80,MTTP,SLCO1C1,NOVA1,NRGN,PAH,PCDH8,PCDH9,ABCB1,FAM216A,MAPKAP1,STRN3,SLC36A4,NXPH1,SH3KBP1,PPP2R5E,RAB39A,MAPK4,CNTLN,PTN,FAM120C,STRC,SLC6A15,REV3L,RFX4,PBRM1,AP1AR,SALL1,SCN2A,SCN8A,SH3GL3,NTNG1,PREX2,SLC11A1,SLIT1,CXXC4,SON,SOX5,SPP1,NXT2,ZSCAN29,SEPT8,DIP2A,PHLDB1,GSE1,SYT1,ADGRL3,TBCEL,TCF4,SYNE1,CRB1,TGFBR3,ZNF384,TRIO,TTC3,WIPF1,CLIP2,ETNPPL,DHX33,MFF,CSDE1,PDSS2,PAK5,ACTR3B,SLC39A12" MicroRNA hsa-miR-615-5p:mirSVR_lowEffct hsa-miR-615-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.39E-65 5.28E-61 3.63E-64 3.34E-63 201 992 "DGCR6,ACHE,ADCY6,CDC7,PNMA8B,ADORA1,ADRA1D,FAHD2CP,AP1B1,RTL9,ZNF578,TAOK1,LRRC7,SEMA6A,MARCH4,SYT13,PDZD4,AMPD3,ANK1,ANK3,PPFIA1,APOC1,BCAS1,AQP6,CDK10,DPY19L3,KSR1,ARHGEF7,AP1M1,CACNA1I,CABP7,TRIM41,CAST,LDB2,P2RX6,LOC730101,SRSF11,CHRNA4,ARHGAP22,FADS2,WHRN,TOGARAM2,ZNF521,SEC31B,CDC42BPB,CSF1,RGS6,GREB1,NRSN1,PUM1,NOS1AP,HDAC9,HDAC4,KCTD8,IP6K1,AIF1L,ELMSAN1,RUSC2,GUCD1,SV2B,SV2A,SRGAP3,DNAH9,ECM2,DNAJB6,SGK2,APH1A,SORBS3,EPB41L2,ENPP6,MRPL37,APC2,CHST15,FGF11,FGFR1,FGR,AMOTL2,TMEM175,UFM1,GABRB3,NEU3,GGT7,GK,ZNF276,PCDH11X,STARD3,GPD1,C1QL4,ADAMTS13,GRIN2C,LINC00839,TMEM25,LINGO1,TMEM179,SYNPO,IGFBPL1,CELF5,MYLK2,KNDC1,LRRCC1,DISP2,SCRT2,INPP5B,SLC6A17,ITGAV,KCND1,KCNH1,KCNQ3,KIFC3,L1CAM,ASPRV1,PIK3AP1,MBD1,MEF2C,DBNL,MSRA,PTOV1,LAYN,HNRNPM,RCOR2,CCDC13,NUCB1,LOC100128398,PALM,ZDHHC8,NLGN3,PKD1,PKM,EPN1,PNMA3,ING3,PPP2R5C,VSTM2L,MAPK7,MAPK9,PTCH1,PYGM,RAB5B,RGS12,MYH14,ARMC5,CARF,RPE,EPHA10,MEG3,HSD11B1L,ST6GALNAC6,KCNIP3,RXRG,LRRTM4,SCN8A,CASC3,ITSN1,SHMT2,FHOD3,ZNF365,SLC1A3,SMTN,SLC6A7,RAB3GAP1,SLC9A5,NAXD,MAPKBP1,MBD5,FAM219A,IZUMO4,KDM4C,RAP1GAP2,PBLD,DIP2A,STAC2,SYN1,ARC,ASTN2,ZEB1,SZT2,FAM189A1,SLC19A3,HIF3A,ATP13A2,PMS2CL,DICER1-AS1,THRA,MTMR14,KCTD2,NPL,SMUG1,AMACR,WNT7A,GUSBP1,LGI4,SPHK2,ZNF189,PMEPA1,PRDM2,DNALI1,LMAN2L,ITM2C,SLC17A6,PDSS2,FAM219B" MicroRNA hsa-miR-124:mirSVR_highEffct hsa-miR-124:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.30E-64 7.31E-61 5.03E-64 4.63E-63 213 1105 "ERMN,PLEKHH1,SLC44A5,ZNF608,RTL9,OSBPL8,CC2D2A,TAOK1,SEMA6A,ZNF687,LCORL,ANXA7,PPP4R4,ARHGDIA,ASPA,DDX3Y,ATP1A1,ATP2B2,LINC00847,BCL7A,NRP2,MYRF,KALRN,PTBP2,USP2,TMEM257,CD81,CDH2,LHX2,NRXN1,TJP2,QKI,CNTN1,AKAP6,RTTN,CLOCK,ANKRD44,SNCAIP,VCAN,SOCS5,CTNND1,EDRF1,HDAC9,GAPVD1,DAPK1,FBXL5,RHOBTB1,SPOCK3,G3BP2,EXOG,DYRK1A,DNM1L,E2F5,SNX29,EDNRB,HIPK3,SEMA3D,FSD1L,STARD3NL,EPS8,FER,PRKAG2,SUCO,SYNCRIP,POMT1,ZNF605,GABRG2,GAD2,NEK6,IQGAP2,DISC1,KIAA1841,ARFIP1,GDF9,PCDH17,GHR,CRCP,RAB30,GLRB,KIAA1958,GPT2,GPD2,CECR2,GRIA2,GRIA4,GRID1,NR3C1,GSN,LINC00839,KAT7,AP4S1,SOX21,IRAK3,MYLK2,IL6R,ITGA7,SLC35G1,KCNK2,KIF2A,KLC1,LIMS1,PAXBP1,VWA5A,HECTD2,ARHGAP12,ASPRV1,MARK1,MAT2A,MBNL1,POC1B,MITF,BCO1,MSRA,NAP1L3,NEUROD1,NFE2L2,NME4,NRCAM,NUMA1,KCNK10,PCDH8,PCDH9,PCSK2,PDE4B,GNG2,GDAP1L1,SSH1,PIK3C2A,RETREG1,JAKMIP1,SMOX,PRRX1,ING3,SH3KBP1,PPP3CB,PKN2,MDGA2,MTMR10,SPDL1,TMEM260,PTPRB,OCIAD1,PTPRD,FAM120C,C1orf109,PTPRZ1,ACSS3,RAD17,ZYG11B,RFX4,RGS12,SLC25A36,SUGCT,GSTCD,CCDC25,ELP2,NEK11,ATP8B4,SOX8,RYR1,RYR3,SEMA6D,SCN7A,CASC3,GALNT10,SGK1,SH3GL3,NTNG1,SHC4,SLITRK3,FAM81A,ATF7IP,TET1,ZKSCAN3,ZNF667,SMARCE1,TTC17,LIMCH1,PALLD,TNIK,ZCCHC24,BDP1,ZC3H13,ITPRID2,KANK1,PLCB1,SYPL1,ANO4,PCDHGA11,PCDHA5,DDHD1,TMOD1,C9orf85,TUB,UBE3A,USP1,WIPF1,CLDND1,ETNPPL,SF1,FSTL5,EML6,ZNF189,SMARCAD1,WNK1,CSDE1,EVI5,SEMA3B,PHTF2,CASC15,JMJD1C,FXR1,CPNE4" MicroRNA hsa-miR-96:PITA hsa-miR-96:PITA_TOP PITA 2.16E-64 1.21E-60 8.32E-64 7.66E-63 120 358 "ABAT,XKR4,SLC25A25,ADCY6,SLC12A5,SNX30,SLC24A4,LRRC7,SEMA6A,ALK,OGT,LRCH2,C6orf89,BRINP2,B3GALT2,DPY19L3,ADGRB3,MTMR3,JAZF1,CACNA1G,NIPA1,CDK5R2,LDLRAD4,CACNB4,THSD7A,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,NRXN1,CLTC,MAP4K4,NIPBL,CNN3,CABP1,MYRIP,CDC42BPB,LRIG1,RIMS4,ERC2,CTNND1,ARHGAP24,FRMPD4,TM9SF4,C8orf34,CEP170,E2F5,SNX29,EIF5,GPHN,FOXF2,FAM49B,ST6GALNAC3,FYN,BRPF3,B4GALNT1,PCDH17,SPIN1,GPM6A,RAPGEF4,GRIA1,GRID1,GRM1,GRM7,ZHX1,MBNL1,CHIC1,MITF,NEXMIF,NOVA1,NPTX2,IGSF11,GPR85,PIK3C2A,ANLN,EPB41L4B,SH3KBP1,MED1,ATG16L1,BSDC1,ZFHX4,MCMBP,ATXN1,SOX6,TRIM46,MRAS,MAGI3,FAM81A,PPP4R3A,BTBD3,CPEB4,MYO16,SOX5,RAP1GAP2,EPB41L3,LRRC4,SS18,KLHL7,COBL,TAC1,TACC1,CAMTA1,FBXW11,TBL1X,TBX15,TCF4,SIN3B,ARHGEF12,ZIC2,ZIC3,TRIM9,TMEM198,ZFAND5,PMEPA1,NAV3,ST7,JMJD1C,SLC4A10,GAN" MicroRNA hsa-miR-125b-5p:TargetScan hsa-miR-125b-5p TargetScan 2.27E-64 1.28E-60 8.76E-64 8.07E-63 161 654 "CPNE2,ABAT,ASIC1,ACHE,ABHD6,FAM43B,NDRG3,ADD2,LRFN2,MTUS1,PKP4,APC,BCL2L2,BMPR1B,MTMR3,NIPA1,BSN,DIRAS1,BRSK2,AIFM1,ARHGEF1,SCARB1,NUMBL,FOXN3,RAB3C,B4GALT6,NRXN1,DNAJB5,QKI,COL11A2,IFFO1,BAG4,ENTPD4,HAPLN1,HINFP,ANKRD44,NCOR2,NCAN,PHACTR3,FAM131B,PHYHIP,IST1,IP6K1,DNAL1,ELMSAN1,DCTN1,RUSC2,FAM107B,ABCC5,FAM135B,PHC2,HIPK3,CNNM1,ABI2,ELAVL4,ANKRD13B,ERBB2,ERBB4,CACNG2,CORO2B,FGF14,FGFR1,C2orf88,DPYSL4,CGREF1,GPR153,NRG3,KIAA1841,GGT7,LPAR4,CECR2,RAPGEF4,GRB10,RFFL,BTN2A1,GSTM5,IL1RAPL1,ATOH8,FRMD5,MAN1B1,HMGCR,HNF4G,OPALIN,MSL1,IL6R,SCRT2,ITGA7,KCNA1,KCNB1,KCNC2,KCNH1,KCNJ9,LIFR,MBD1,ADAM11,MEIS2,MSI1,C10orf105,SAMD14,MYO9A,MYT1,HCN1,IGSF11,CHAMP1,KCNK10,PAK3,KCTD15,DRAM2,PPP2R5C,MAPK10,PROX1,CNNM2,PTH1R,C1orf109,FAT4,RASGRF1,RASGRF2,DPF2,RFX3,RFX5,LGI2,RORB,RIMKLA,EMID1,KCNIP3,AMER2,MAPK12,CSRNP3,ATXN1,ATXN7,SCN2B,SCN4B,COPZ1,CPEB3,MYO18A,CPEB4,ABTB1,FAM126B,KDM4B,CDK19,ELOVL4,ACSL6,SATB2,CRTC1,DICER1,ASXL3,DAAM2,RBFOX2,NPL,CLIP2,KLC2,CRB2,LYPD6,POLR3H,DHX33,GDPD5,PARP11,RGS7BP,GOPC,MSRB3,LAS1L" MicroRNA hsa-miR-125a-5p:TargetScan hsa-miR-125a-5p TargetScan 2.27E-64 1.28E-60 8.76E-64 8.07E-63 161 654 "CPNE2,ABAT,ASIC1,ACHE,ABHD6,FAM43B,NDRG3,ADD2,LRFN2,MTUS1,PKP4,APC,BCL2L2,BMPR1B,MTMR3,NIPA1,BSN,DIRAS1,BRSK2,AIFM1,ARHGEF1,SCARB1,NUMBL,FOXN3,RAB3C,B4GALT6,NRXN1,DNAJB5,QKI,COL11A2,IFFO1,BAG4,ENTPD4,HAPLN1,HINFP,ANKRD44,NCOR2,NCAN,PHACTR3,FAM131B,PHYHIP,IST1,IP6K1,DNAL1,ELMSAN1,DCTN1,RUSC2,FAM107B,ABCC5,FAM135B,PHC2,HIPK3,CNNM1,ABI2,ELAVL4,ANKRD13B,ERBB2,ERBB4,CACNG2,CORO2B,FGF14,FGFR1,C2orf88,DPYSL4,CGREF1,GPR153,NRG3,KIAA1841,GGT7,LPAR4,CECR2,RAPGEF4,GRB10,RFFL,BTN2A1,GSTM5,IL1RAPL1,ATOH8,FRMD5,MAN1B1,HMGCR,HNF4G,OPALIN,MSL1,IL6R,SCRT2,ITGA7,KCNA1,KCNB1,KCNC2,KCNH1,KCNJ9,LIFR,MBD1,ADAM11,MEIS2,MSI1,C10orf105,SAMD14,MYO9A,MYT1,HCN1,IGSF11,CHAMP1,KCNK10,PAK3,KCTD15,DRAM2,PPP2R5C,MAPK10,PROX1,CNNM2,PTH1R,C1orf109,FAT4,RASGRF1,RASGRF2,DPF2,RFX3,RFX5,LGI2,RORB,RIMKLA,EMID1,KCNIP3,AMER2,MAPK12,CSRNP3,ATXN1,ATXN7,SCN2B,SCN4B,COPZ1,CPEB3,MYO18A,CPEB4,ABTB1,FAM126B,KDM4B,CDK19,ELOVL4,ACSL6,SATB2,CRTC1,DICER1,ASXL3,DAAM2,RBFOX2,NPL,CLIP2,KLC2,CRB2,LYPD6,POLR3H,DHX33,GDPD5,PARP11,RGS7BP,GOPC,MSRB3,LAS1L" MicroRNA "TGGTGCT,MIR-29C:MSigDB" "TGGTGCT,MIR-29C:MSigDB" MSigDB 2.28E-64 1.28E-60 8.79E-64 8.09E-63 138 480 "DPF1,ASIC1,XKR4,PITPNM2,ANK3,PARG,GPAM,DGKD,USP37,ASPH,ATP2B1,N4BP2L1,BCL7A,CAMK2G,CDC42,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,IFFO1,CREB5,NCOR2,CTNND1,FAM131B,HDAC4,DBT,ELMSAN1,SRGAP3,FAM57B,ARRDC4,FEM1B,KMT5B,PLEKHA1,ANKRD13B,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,STAG2,GAB1,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,ADAMTS13,RNF165,ADAMTS6,KLF12,BACH2,HMGCR,HNF4G,IGF1,TUBB2B,KCNMA1,TTYH2,MAP6,MAT2A,MYCN,MIR4697HG,NAP1L3,NASP,NFIA,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,SIDT1,DEF8,PTHLH,EML5,PEX5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,KCNIP2,ATXN1,SMPD3,SFPQ,SGK1,PPM1E,CPEB3,SLC1A2,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,C11orf87,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ZFP91,TPM1,ZNF346,TUBB2A,AMOT,NSD2,NDRG4,PLPPR5,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,NAV2,GOPC" MicroRNA "TGGTGCT,MIR-29A:MSigDB" "TGGTGCT,MIR-29A:MSigDB" MSigDB 2.28E-64 1.28E-60 8.79E-64 8.09E-63 138 480 "DPF1,ASIC1,XKR4,PITPNM2,ANK3,PARG,GPAM,DGKD,USP37,ASPH,ATP2B1,N4BP2L1,BCL7A,CAMK2G,CDC42,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,IFFO1,CREB5,NCOR2,CTNND1,FAM131B,HDAC4,DBT,ELMSAN1,SRGAP3,FAM57B,ARRDC4,FEM1B,KMT5B,PLEKHA1,ANKRD13B,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,STAG2,GAB1,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,ADAMTS13,RNF165,ADAMTS6,KLF12,BACH2,HMGCR,HNF4G,IGF1,TUBB2B,KCNMA1,TTYH2,MAP6,MAT2A,MYCN,MIR4697HG,NAP1L3,NASP,NFIA,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,SIDT1,DEF8,PTHLH,EML5,PEX5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,KCNIP2,ATXN1,SMPD3,SFPQ,SGK1,PPM1E,CPEB3,SLC1A2,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,C11orf87,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ZFP91,TPM1,ZNF346,TUBB2A,AMOT,NSD2,NDRG4,PLPPR5,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,NAV2,GOPC" MicroRNA "TGGTGCT,MIR-29B:MSigDB" "TGGTGCT,MIR-29B:MSigDB" MSigDB 2.28E-64 1.28E-60 8.79E-64 8.09E-63 138 480 "DPF1,ASIC1,XKR4,PITPNM2,ANK3,PARG,GPAM,DGKD,USP37,ASPH,ATP2B1,N4BP2L1,BCL7A,CAMK2G,CDC42,QKI,MAP4K4,CNR1,PCYT1B,ARMC8,COL4A5,COL9A1,IFFO1,CREB5,NCOR2,CTNND1,FAM131B,HDAC4,DBT,ELMSAN1,SRGAP3,FAM57B,ARRDC4,FEM1B,KMT5B,PLEKHA1,ANKRD13B,SCML2,MED12L,BAIAP2,MEX3B,RGPD5,STAG2,GAB1,PPARGC1A,RND1,RAB30,FERMT2,EML4,GPR37,ADAMTS13,RNF165,ADAMTS6,KLF12,BACH2,HMGCR,HNF4G,IGF1,TUBB2B,KCNMA1,TTYH2,MAP6,MAT2A,MYCN,MIR4697HG,NAP1L3,NASP,NFIA,NFIX,OXTR,PALM,NLGN3,PIK3R1,CCSER2,KCTD15,PLP1,PURG,PMP22,STRN3,EPB41L4B,PRKAB2,SIDT1,DEF8,PTHLH,EML5,PEX5,TMEM255A,RAP1GDS1,OXR1,RET,REV3L,LGI2,KIRREL1,FBXW7,KCNIP2,ATXN1,SMPD3,SFPQ,SGK1,PPM1E,CPEB3,SLC1A2,ELMO2,TET1,MAPKBP1,HECW1,SPTAN1,NFASC,C11orf87,ELOVL4,STX1A,CAMTA1,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,DICER1,AP4E1,ZFP91,TPM1,ZNF346,TUBB2A,AMOT,NSD2,NDRG4,PLPPR5,SLC30A3,EMSY,XKR7,ADAMTS9,NAV3,NAV2,GOPC" MicroRNA hsa-miR-409-5p:mirSVR_lowEffct hsa-miR-409-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.64E-64 1.48E-60 1.01E-63 9.34E-63 171 736 "SDE2,TKTL1,KLHL32,KIDINS220,BEND6,OSBPL8,BCAR3,ABCD2,ANK3,FGD2,CADPS,ZBTB10,NOL4,ADAM23,ADGRB3,SYNJ1,CALB1,PTBP2,CAST,RGN,CD38,C1orf52,DGKI,CDC25B,LOC730101,CASC2,NRXN3,PLAA,NRXN1,MFSD4A,OSBPL3,CCDC144A,DOCK4,HDAC9,TOX,YTHDC1,ZEB2,MYEF2,KIF19,FCF1,TMTC1,SUGP2,TENM1,C8orf37,USPL1,EIF1,LRRC17,SRARP,RASL12,ATP8A1,ZSCAN30,SEC24B,FER,OLFM1,FGF12,POLK,FOXG1,SEMA4D,NBEA,DACH2,CSPG5,SDCBP2,CHL1,AHCYL1,IP6K3,DISC1,DCLK2,GPD1,GPM6B,TMEM121B,PCLO,GRM3,FAM19A2,PSIP1,ADAMTS6,TLX1,IL11RA,IL12A,INSM1,ITGAV,KCNA1,KLC1,LAMA2,SYT9,AFF1,CCDC80,TMEM249,RSPO2,NFE2L2,GPR88,OPA1,OPRL1,GPR137C,PAH,CNTN3,PFKFB2,A2ML1,SNX10,EPB41L4B,SLC36A4,DRAM2,PTPA,PKN2,VPS13C,SLC22A23,TMEM260,FAM120C,DBX2,REV3L,MORC4,RGS4,RGS12,KIF7,RPL15,ACER3,KCNIP3,RTN1,AP1AR,SEMA6D,HES6,ELMOD1,SOX6,SH3GL2,SH3GL3,NTNG1,SYBU,WDR37,DHX30,RUFY2,RAB3GAP1,SPHKAP,MYH15,SMARCE1,MBD5,SON,CLUAP1,PEG10,KIF1B,NFASC,TAB2,ITPRID2,SAMSN1,NXT2,SYT11,ARHGEF9,VPS13A,KIAA1107,RPGRIP1L,SIK3,AP4E1,HEY2,TMPO,C5orf64,ZNF384,TRPS1,LRTM2,TUB,RPL7L1,OSBP2,VLDLR,PCDH20,PRDM2,SNX27,WNK2,EPM2A,RGS7BP,PHTF2,FBXO36,FRMD6,CBLN2,SOCS4" MicroRNA hsa-miR-4260:mirSVR_highEffct hsa-miR-4260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.08E-64 1.73E-60 1.18E-63 1.09E-62 149 562 "GPRIN1,XKR4,BRAP,ADRA1D,RTL9,ALCAM,ARHGAP20,AMT,FGD2,CNIH2,PPFIA1,CNTNAP1,KCNAB2,EPB41L5,PHYHD1,TNRC6C,PPFIA3,SHROOM2,SFMBT2,ATP1A3,RNF182,BACH1,BTK,SCAPER,MYRF,RUNX1T1,USP2,INA,SRSF11,CHRM1,JAM2,NIPBL,SUMF2,ANKRD44,CLIP3,SEC24C,CSF3R,ATRNL1,VCAN,CTNND1,TBC1D5,ZEB2,MYEF2,ZC3H11A,DDX46,POM121,SPOCK3,DNM1,DPP6,GNE,PHF20L1,EIF5,C8orf37,RCAN2,LRRC23,LRRC17,STX2,RAB9B,SIRPB1,F5,TESK2,MED12L,POLK,FLT1,C2orf88,SORBS1,ARFGAP2,CELF1,MEGF11,TRAF3IP2,STARD10,GATM,ALDH1L1,LOXL3,DIDO1,GRIK1,RNFT2,ATOH8,VSIG4,ELOVL5,AGBL5,IDH3B,DOCK7,KCNJ9,KCNJ10,MAG,MATN2,SYT9,MSR1,NKX2-2,NME4,SLC11A2,TBC1D25,GPR137C,PBX1,PCSK2,PDGFRA,GDAP1L1,SEMA5B,SNX10,PCDH18,POLG,FSD1,GON4L,CASTOR1,PTPRZ1,NKAIN1,RAB3A,RAB3IL1,SLC25A48,SUSD4,FIGN,RIC8B,CARF,ATP8B4,RXRG,DGLUCY,ASAP3,SEC31A,ZNF365,SLC6A11,ATF7IP,BDP1,PEG10,TAB2,SEPT3,ARHGEF9,RNF216P1,TGFBR3,THRA,MTMR14,CSMD1,ZNF384,TRIO,TRPC3,NUTM2A,GORASP1,OSBP2,BEST1,P2RY12,SLC13A3,ZNF540,LAMP5,HPS4,NAV3,NELFE,DOCK8,SMIM8,NETO2" MicroRNA hsa-miR-3126-5p:mirSVR_highEffct hsa-miR-3126-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.42E-64 1.92E-60 1.31E-63 1.21E-62 150 570 "NBAT1,SORCS1,ADORA2A,ADRA1D,ADRA1B,RTL9,ALAD,VAT1L,ARRB1,ATP1B3,CASTOR3,BAIAP3,IL33,CANX,SLC16A4,SEPT7,CDC27,CHN2,EPS15L1,NRXN2,SLC24A2,NMT2,CLTB,TMEM155,AKAP6,BTF3L4,ABI3BP,ACBD5,MFSD4A,ZNF385A,FAM171B,CRY2,CLIP3,MROH8,CSF1,PDE4DIP,CCDC144A,ZNF337,DCTN1,MAGI2,SV2A,NTM,DLG2,DLG3,DYNC1I1,DTNA,EIF4G2,C8orf37,EIF1,SEZ6,F5,ZSCAN30,FGFR1,ERGIC3,ZNF512,GABRA3,AHCYL1,WASF3,GGT7,ZNF638,LOXL3,ADGRA3,FUT10,EML4,RAPGEF1,GRIA4,LINC01551,MSL1,DISP2,IL11RA,IL12A,SLC35G1,KCNJ5,KCNMA1,KIF5A,PAXBP1,PIK3AP1,MAP6,SYT9,SHC3,MID1,BCO1,NELL1,LRIT2,NPR2,NUMA1,PAK3,PCSK1,CDK18,FTO,FXYD1,C11orf49,TNPO2,POU6F1,HYDIN,SAMD9,SIDT1,GDPD2,PSMD13,TMEM260,ACSM5,RAB5B,EXD2,NEK11,MCMBP,KCNIP1,FAM192A,PRCD,FNIP1,TRIM46,SFPQ,ASAP3,BCAN,SLC2A5,BTBD3,FAM214B,SLC8A3,SCMH1,NAXD,ZNF667,IDI2-AS1,SS18,SSPO,SEPT3,VAMP1,VPS13A,VWA3A,VWC2,SATB2,ZEB1,SYNE1,AP4E1,SLC44A1,PRRT1,PIK3R5,SEZ6L,TPM3,PRMT8,FLRT2,FAM181B,ZNF781,FMN2,FTSJ1,STOX2,CIAPIN1,SLC17A7,C12orf4,DOCK8,HNRNPA3,SLC4A10" MicroRNA hsa-miR-1258:mirSVR_highEffct hsa-miR-1258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.03E-64 2.83E-60 1.93E-63 1.78E-62 167 706 "ACTN2,SLC25A25,KLHL32,AXIN2,BEND6,TBC1D14,WDR35,OSBPL8,ALCAM,LCORL,TNRC6C,ASCL1,CAPRIN2,ASPH,ATP1B3,ATP2B3,BID,GYG2,PTBP2,LGI1,SRSF11,RAB3C,ARMC8,ZFP28,HAPLN1,ANKRD44,NCOR1,CSF1R,ARHGEF10,ATRNL1,VCAN,DOCK4,KCTD8,DAPK1,SCRN1,GIT2,ARMCX4,ZEB2,MAGI2,PLPPR4,SGSM2,WDR20,ACOT8,ECM2,FRY,PHF20L1,EMX2,EPHB1,KCNMB2,ERBB4,TMEM74,ZIC4,EFEMP1,FCGRT,FGF1,FGF12,SEC23B,ZCCHC17,STAU2,SDCBP2,AHCYL1,ZMYND11,DISC1,DNER,GFRA2,CSDC2,PPARGC1A,RAB30,GNAS,GPT2,TDRKH,CCDC184,GRIA2,GRIA4,PLCD4,GRIK1,ADAMTS6,GUCY1B1,FAM222A,LRRC25,RBPJ,OLFM3,KCNC2,KLHL23,KCNN2,CREG2,MBP,MMP16,MSI1,ZNF862,MYT1,FXYD6,NEK1,HCN1,OCRL,PCSK1,PDYN,GNG2,NALCN,PMP22,TRHDE,PSAT1,PPARA,PPP2R5E,RANBP3L,PTPRE,TMEM255A,ZNF493,RADX,SLC6A15,ZYG11B,GTDC1,ZFHX4,CARF,CNTNAP3,ABCA11P,LRRTM4,SEC14L1,SOX6,KIF21A,CHD9,CNKSR2,ST3GAL3,SLC1A6,SORCS3,ZNF415,WDTC1,SPART,CLSTN2,DIP2A,VAMP1,SYT1,C12orf76,TCF7L2,TCF12,DOCK9,OBSL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LEFTY2,TIAM1,TJP1,R3HDM1,TPM1,ANO5,TTPA,SGK3,FAM155A,UBE2H,UGT8,FMN2,ZNF74,ZNF138,SMARCAD1,PRDM2,RNF103,ADAMTS9,FIP1L1,WNK3,PAK5,SLC4A10,SPATA13" MicroRNA hsa-miR-152:PITA hsa-miR-152:PITA_TOP PITA 5.41E-64 3.04E-60 2.07E-63 1.91E-62 138 483 "ASIC1,ADCY2,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,APBB1,MIER1,MARCH3,NCOA1,MTMR9,NOL4,ADGRB3,BCL7A,CDK5R1,SYNJ1,BSN,CACNB2,CALM1,CAMK2A,CANX,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,ST18,RUBCN,SNPH,SNAP91,DLG2,RAB39B,DMPK,DYRK1A,ST8SIA3,KLHL5,FRY,EGR3,ELAVL2,EPB41L1,SLC43A2,RTN3,EZH1,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,GAP43,C15orf41,DNER,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,GPM6A,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,C5orf24,KIT,STXBP5,MITF,NCAM1,NDP,NEUROD1,NFIX,NPTX1,NUMA1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,CDK14,PIK3C2A,ANKRD16,POU3F2,MED1,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,ATXN1,SCN2B,PPP1R9A,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,SRPK2,PLCB1,SYT1,SYT4,ATP11A,TCF4,ARHGEF12,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TNFRSF1B,RBFOX2,TRPS1,CADM1,BEST1,TMEM237,SLC38A1,SNX27,RTN4,KAT6A,CERS6,FXR1,JPH3" MicroRNA hsa-miR-148b:PITA hsa-miR-148b:PITA_TOP PITA 5.41E-64 3.04E-60 2.07E-63 1.91E-62 138 483 "ASIC1,ADCY2,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,APBB1,MIER1,MARCH3,NCOA1,MTMR9,NOL4,ADGRB3,BCL7A,CDK5R1,SYNJ1,BSN,CACNB2,CALM1,CAMK2A,CANX,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,ST18,RUBCN,SNPH,SNAP91,DLG2,RAB39B,DMPK,DYRK1A,ST8SIA3,KLHL5,FRY,EGR3,ELAVL2,EPB41L1,SLC43A2,RTN3,EZH1,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,GAP43,C15orf41,DNER,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,GPM6A,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,C5orf24,KIT,STXBP5,MITF,NCAM1,NDP,NEUROD1,NFIX,NPTX1,NUMA1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,CDK14,PIK3C2A,ANKRD16,POU3F2,MED1,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,ATXN1,SCN2B,PPP1R9A,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,SRPK2,PLCB1,SYT1,SYT4,ATP11A,TCF4,ARHGEF12,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TNFRSF1B,RBFOX2,TRPS1,CADM1,BEST1,TMEM237,SLC38A1,SNX27,RTN4,KAT6A,CERS6,FXR1,JPH3" MicroRNA hsa-miR-568:PITA hsa-miR-568:PITA_TOP PITA 5.42E-64 3.04E-60 2.07E-63 1.91E-62 142 512 "CSMD2,PTCHD1,ZNF608,GPR158,OSBPL8,LRRC7,ALCAM,GAS7,CDC14B,ARHGAP5,ASCL1,SLC4A4,FUBP1,BSN,NUMBL,CHN2,KMT2C,NIPBL,SLC4A7,IGDCC3,CSNK1G3,ATRNL1,SOCS5,PHACTR3,PUM1,MATR3,MAML1,CNIH3,DDX46,RHOBTB1,SPOCK3,DLG2,DLG3,DLX1,ABI1,MAMLD1,EIF5,ELAVL2,ZIC4,MED12L,NBEA,SORBS1,FUT9,STAG2,CHL1,GABRB3,BRPF3,PPARGC1A,GK,SPIN1,KDM2B,GPM6A,EML4,FAM19A2,PSIP1,ZHX1,MIER3,HLF,ELOVL5,AGFG1,IGF1,C5orf24,ZIC5,BRINP3,JAK1,KCNA4,KIF5C,IPO5,PACRG,MAP2,MARK1,MATN2,LRP1B,MEIS1,KITLG,MITF,NEUROD1,NF1,NFIX,KSR2,PDGFRA,XRN1,STRN3,MED1,PPP3CB,PRKAB2,GDPD1,TMEM260,PTPRG,FAM120C,RAB5B,TMEM255A,SH3TC2,OXR1,FEZF2,SLC6A15,REV3L,RORB,ZC3H14,SEMA6D,SUPT20H,FHOD3,NLGN1,ELMO2,CPEB4,SMARCA4,PDZRN3,PDZD2,SOX1,ZCCHC24,SP4,HECW1,MYCBP2,ADAMTS17,SYT1,ANKRD28,SYT4,ANKRD12,CAMSAP2,FBXW11,TCF4,TCF12,ARHGEF12,TJP1,LRRC8A,RIMBP2,CSMD1,KAT6B,FAM155A,XPO1,ZBTB38,SMARCAD1,PMEPA1,CADM2,LRP8,SLC17A6,RGS7BP,GOPC,FAM13C,FRMD6,ST8SIA2,CPNE4" MicroRNA hsa-miR-147:mirSVR_highEffct hsa-miR-147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.67E-64 3.19E-60 2.17E-63 2.00E-62 169 723 "ACLY,ABHD6,SLITRK1,ADD2,AXIN2,FAHD2CP,BEND6,KCTD16,NR0B1,AMPH,ZFAT,ANK2,ANK3,MAP4K3,MYH7B,PKP4,PARG,FAM131A,APP,LINC00847,BID,KALRN,CAMK2D,CAST,CCK,LDB2,CBFA2T2,CHGB,CHN2,SYNPR,RAB28,AKAP6,BTF3L4,AKAP12,SNCAIP,FEZ1,CSNK1E,ATRNL1,NRSN1,CYBB,DCAF8,SPOCK2,ZEB2,MYEF2,CNIH3,FBXL5,SV2A,DMTF1,EDN1,FAM135B,KMT5B,ELAVL4,RGS17,RABEPK,MRVI1,F5,F8,FAM198B,CACNG3,RACK1,FDFT1,TESK2,MEX3B,NOP56,ADGRA1,GABRA1,AHCYL1,JPH4,ERAP1,SYT17,DISC1,TUBGCP4,RND1,COPS8,ZNF638,MAP7D2,PRUNE2,RAPGEF4,GRIA4,NR3C1,GRM5,MAEL,HSF2,IL6ST,ITGAM,CDH20,CYP27C1,L1CAM,LMO2,HECTD2,MAT2A,SYT9,POC1B,MSR1,MTTP,NF1,GPR88,LOC100128398,ZNF827,PCDH8,PCMT1,PDE1C,ENPP2,ZDHHC8,PLCL1,PCDH18,PURG,PPM1B,PPP3CB,HYDIN,MASP1,GDPD2,CNTLN,STK32A,PTPRD,PTPRG,ACSM5,FAM66C,RAP1GDS1,RASGRF2,DBX2,RFX4,RFX5,RGS3,NUDT11,PBRM1,RPRD1A,TMLHE,ROBO2,CCDC102B,ATP8B4,ACER3,SARS,TNFRSF19,FERMT1,SYBU,PPP4R3A,SLC8A3,ELMO2,ATF7IP,TET1,SLN,SORCS3,SCN3B,WDTC1,KIF1B,C11orf87,AJAP1,SYT11,SYNE2,FNDC9,CAMTA1,KLHL4,RPGRIP1L,GPRIN3,SLC44A1,TP53BP2,RGMB,TRO,HSPBP1,TMEFF2,HIRA,BEST1,ZNF28,TRIM9,LINC00632,RTN4,PHTF2,CPNE4" MicroRNA hsa-miR-3161:mirSVR_highEffct hsa-miR-3161:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.13E-64 3.45E-60 2.35E-63 2.16E-62 183 842 "RALGAPA1,KCNH8,CSMD3,ADORA3,PTCHD1,BEND6,KIAA1324,AMPD3,ALS2,SHTN1,MIER1,ASPH,DPY19L3,ATP6V1G2,BCL7A,NRP2,CAMK2D,CBR1,AIFM1,LGI1,MS4A7,NDST3,NRXN3,IGFBP7-AS1,NRXN1,FAM19A5,TMEM155,AKAP6,ABI3BP,BAG4,CNRIP1,PNKD,HAPLN1,RNF14,CRYM,CSNK1G3,SOCS5,DZIP3,PHF14,PLCXD3,HDAC9,TMEM170A,SNAP91,HS3ST2,DNAH9,DYRK1A,EBF1,KLHL5,RBM12,YAF2,PHF20L1,KMT5B,PLEKHA1,EN2,RRAGB,ACSL4,CEP78,FGF13,SUCO,ZBED3,ST6GALNAC3,PHYHIPL,CAB39,RAPGEF6,NEK6,ZNF559,DISC1,PPARGC1A,ZNF638,GOLGB1,GRIA1,DIDO1,NR3C1,RNF165,GYG1,NCKAP1L,LINC01102,ELOVL5,HMGB1,ZDHHC15,ZNF678,KCNMA1,VWA5A,CTNNA3,PABPC1L2A,P2RY13,NCAM2,NDUFA5,NELL1,NEK1,NFE2L2,CNOT4,NOVA1,GPR88,OPCML,GPR137C,PCSK5,PCSK2,ENPP2,SNX10,PLIN1,SPATA6,CRLS1,PKIA,MAPK9,GDPD1,MASP1,SAMD9,MDGA2,PIGG,PTCH1,PTHLH,PTPRE,PTPRG,PTPRO,DBX2,ZMAT4,RET,ERI2,RFX3,RGS12,RIC8B,ZNF532,ROBO2,LRRK2,ATAT1,CLIP1,RTN1,ZNF568,SALL1,ATXN7,LRFN5,LRRTM4,FAM19A1,SEC14L1,SUPT20H,ITSN1,FERMT1,CHD9,FBXO11,FHOD3,SLITRK3,ZNF365,SLC1A3,SEPHS1,SPHKAP,GKAP1,IFT122,SOX5,LMO3,NXT2,MPRIP,STXBP1,VPS13A,TACR1,KIAA1107,EHBP1,DMXL2,ZEB1,SYNE1,PCDHB7,NSD1,USP32P1,FAM200B,CRB1,ZFP91,ERCC6L2,TNFRSF1B,C9orf85,ANO5,CLHC1,CADM1,RPL7L1,RICTOR,TRIM9,ZNF540,SMARCAD1,SYNC,EMSY,MPPE1,AMN1,NETO2,FAM198A" MicroRNA hsa-miR-31-5p:TargetScan hsa-miR-31-5p TargetScan 7.00E-64 3.93E-60 2.68E-63 2.46E-62 116 336 "ARID1A,NDRG3,ADCY6,KIAA1211,AK2,PDZD4,PHF12,APBB2,EPB41L5,APP,ARRB1,NUMB,DPY19L3,FUBP1,JAZF1,CACNB2,CAMK2D,CAMK2G,FMNL3,CCNT1,DGKI,ARHGEF2,CLCN3,QKI,CLOCK,PREPL,PLXNA4,CTH,CTNND2,FRMPD4,RIMS3,CTIF,RHOBTB1,DMD,FAM135B,EDNRB,CNNM1,HEYL,RBM12,EIF5,ELAVL2,PLEKHA1,EIF1,COQ7,RAB9B,CEP85L,ATP8A1,ANKFY1,KHDRBS3,GABBR1,GABRA3,AHCYL1,GRB10,GRIK3,MAP4K5,BACH2,KCNN3,LSAMP,AFF1,MMP16,MYO5A,HCN1,OPRL1,PC,PCDH8,PDE4D,PDPK1,GDAP1L1,PIK3C2A,FTO,CDIP1,PPP3CA,PKN2,FITM2,PXK,EML5,PTPRG,PEX5,RAB5B,RDX,GTDC1,FIGN,RGS4,GSTCD,CSRNP3,SCN2A,PPP1R9A,RPH3A,LRRC55,ATF7IP,EPC1,PDZD2,IQSEC2,C11orf87,CLASP2,CLSTN2,KANK1,RHBDL3,MMS19,ATP11A,EHBP1,SATB2,GPRIN3,DICER1,HHIP,CBX5,CSMD1,IL34,NR2C2,FNDC5,OSBP2,POLR3H,DPYSL5,CIAPIN1,FZD3,FXR1" MicroRNA hsa-miR-579:PITA hsa-miR-579:PITA_TOP PITA 7.89E-64 4.43E-60 3.01E-63 2.77E-62 131 435 "CSMD3,ADARB2,DSCAML1,SNX30,GPRASP2,OGT,DPP10,PKP4,APAF1,APC,GPAM,LRRC4C,TMEFF1,CADPS,MARCH3,ZBTB10,PROM1,CACNB4,CALB1,CALM1,TMEM257,CDC42,CDH10,LGI1,B4GALT6,MAP4K4,CNR1,AKAP7,SLC4A7,AHCTF1,NSL1,RBM39,CREB5,APPL1,CTNND1,ST18,DOCK4,KIF26A,LONRF1,TIAM2,G3BP2,FAM107B,DLG2,DMD,CALN1,ABI2,TENM1,EPB41L2,GPHN,ERBB4,ETV1,FOXO3,AFF2,NBEA,ATP2C1,STAG2,MEGF10,IQGAP2,PCDH17,PPARGC1A,DHRS4,GLRB,GNAS,MAP4K5,HAS2,DDX19B,KLF12,BACH2,AGFG1,SMAP1,C5orf24,KCNA1,KCNA4,KCNC2,LIMS1,SMAD1,MAPT,MITF,RSPO2,ZC3H12B,NOVA1,KCNK10,PDE4D,ZNF655,STRN3,FAT3,POU3F2,MED1,PKN2,PTPRD,FAM120C,TMEM255A,REV3L,FIGN,SLC25A36,ZFHX4,SETD5,ROBO1,SEMA6D,SCN3A,SOX6,PPP1R9A,NTNG1,FNDC3A,NLGN1,WDR37,FAM81A,CPEB4,SOX2,SOX5,ZCCHC24,MYCBP2,NPAS3,ERBIN,ELOVL4,TTBK2,SYPL1,TCF4,DMXL2,SIRT1,THRA,TRPS1,UBE3A,GORASP1,ZIC1,INTS3,CADM2,CSDE1,PRDM10,GOPC,HNRNPA3" MicroRNA hsa-miR-188-5p:mirSVR_highEffct hsa-miR-188-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.43E-64 4.73E-60 3.22E-63 2.96E-62 177 792 "GPR158,SPOP,DPP10,USP28,API5,PPFIA3,TMEM263,RGS20,B3GALT2,TTLL9,RGS9,BCL7A,NRP2,DST,ARHGEF7,IL33,KALRN,PTBP2,VXN,CCNH,LRRFIP1,CDH18,MAGI1,KMT2C,CLU,NIPBL,SEC31B,RNF14,FEZ1,VAC14-AS1,CFAP61,BOC,HDAC9,MATR3,DAPK1,ARMCX2,SPATA2,FBXL5,DDX46,NTM,RABGAP1L,DLG3,GRIN3A,SLC12A6,ABI1,RCAN1,WDPCP,SGK2,PHF20L1,ELAVL4,RABEPK,STX2,ZIC4,ST3GAL6,FDFT1,GORAB,KIAA1109,FGF14,SUCO,CAP2,PCYOX1,NBEA,FAM49B,ATP6V1H,STAU2,ARPP21,NEK6,ALDH1L1,GDF9,GLS,ZNF638,INSM2,GOLGB1,FUT10,GRIA2,PLCD4,LINC00839,KAT7,ADAMTS6,MAP4K5,FRMD5,HNMT,NKD1,INSM1,ITGAV,KCND2,KCNK2,LMO2,MBD1,MBNL1,MGAT3,CCDC80,MTTP,PCDH9,PDE3B,PDE4D,CYTL1,CDK14,FAM216A,PLP1,MTRF1L,C11orf49,PRKAB2,VPS13C,CNTLN,PTAFR,PTPRD,PTX3,STRC,CEP97,USP47,GTDC1,RGS10,SEC61A2,ZFHX4,DCUN1D2,SNX22,RPL15,FBXW7,CNTNAP3,ATAT1,ATXN2,ATXN7,FNIP1,KIF16B,DOCK10,CNKSR2,SLC8A3,CCDC88A,EPC1,MYT1L,MYCBP2,KDM4C,NPAS3,ATP10B,LARP4,ELOVL4,GANAB,FGD4,ANKRD12,CAMTA1,AGTPBP1,VWA3A,WASHC4,SZT2,CRB1,ITGB3BP,AP4E1,SLC44A1,GZF1,TIAM1,TIE1,ZFP91,HEY2,TMPO,TRPC1,TSN,RPL7L1,SLAIN1,PITPNB,FLRT2,MEAF6,RICTOR,AGMO,REEP1,UPF3A,PRDM2,STOX2,PRDM8,PCDH15,SLC17A7,MVB12B,PARP11,EPM2A,FAM13C,FZD3,RNF170" MicroRNA hsa-miR-30b*:mirSVR_highEffct hsa-miR-30b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.50E-64 4.77E-60 3.24E-63 2.98E-62 196 959 "ASIC2,EMILIN3,FAM43B,OSBPL1A,ALAD,GPAM,APOC2,MIER1,ARNTL,ARRB2,MARK4,NCOA1,NUMB,CHID1,SLC2A11,ATP6V1G2,TTLL9,CFLAR,ARHGEF7,GYG2,CACNB2,CLDN10,CCK,LDB2,AIFM1,CACNA2D2,CHN2,PPT2,NIPBL,ARMC8,BTF3L4,LETMD1,COL11A2,SLC4A7,CNRIP1,SEC31B,HAPLN1,NCOR1,CS,MROH8,SNCAIP,CSF3R,MICAL2,CSNK1G3,SOCS5,CST3,CMTM5,RIMS2,FGFR1OP2,KATNAL2,ELMO1,FBXL5,SACS,NTM,DLG2,ACOT8,DTNA,E2F5,AASDH,EBF1,PHC2,EFNB3,ABI2,GOLGA7,SORBS3,PLEKHA1,SRRM1,GMPR2,CORO2B,FCGRT,FOXG1,CGREF1,ZNF44,GABRA5,C15orf41,ATP8A2,MYOZ2,GFAP,GFRA2,TNRC6A,STARD3,GPD1,TDRKH,GRM1,GRM5,LINC00839,RNF165,AP4S1,RNFT2,NXPH3,FRMD5,NCKAP1L,ATXN2L,ZDHHC15,HSD17B1,SHISA6,LRRC25,USP54,ZNF678,KCNJ3,KCNJ11,KLRC3,STXBP5,VWA5A,MAG,MAT2A,MBD1,MEST,AFDN,ERICH3,BCO1,CTNNA3,NASP,IDNK,NNAT,NOS1,NOVA2,OGG1,SNTG1,PAK3,GPR173,NALCN,A2ML1,XRN1,PLEC,HMGCLL1,PMP2,NECAB2,PRKCG,PRKCZ,DCHS2,VPS13C,PPP2R3C,TMEM255A,ACSS3,GTDC1,RFX4,RGS4,CARF,ATAT1,KCNIP1,SEMA6D,FNIP1,SH3GL2,SYBU,ZNF365,SLC1A7,WDR47,FAM214B,LRRC55,SCMH1,ATF7IP,ZNF667,MYO16,SOX5,DBNDD2,SPTAN1,NPAS3,LHPP,TAB2,ZC4H2,ST5,VAMP1,SYN2,SYP,TACC1,TBCEL,FBXW11,ACSL6,DMXL2,ZFP90,SYNE1,USP32P1,TIAM1,TIMP4,ZNF346,SYNPO2,TRIO,STXBP4,FNDC5,RUSC1,RFTN2,CADM1,PLPP4,ZNF189,ANKS1B,FTSJ1,TMEM178A,SCG2,HPS4,TMEM63C,NUP214,ACTR3B,KLHDC1,AP3B2,SLC4A10" MicroRNA hsa-miR-1182:mirSVR_highEffct hsa-miR-1182:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.69E-64 4.88E-60 3.31E-63 3.05E-62 157 628 "KCNH8,ABHD6,ARID1A,CC2D2A,ALCAM,GPRASP2,PHF12,SUGT1P4-STRA6LP-CCDC180,API5,CASK,ATM,RNF182,BACH1,SEC11C,BLM,CACNA1G,CACNA2D1,CACNB2,CACNB4,KALRN,CAMK2G,CAST,NFS1,PRC1,MTMR7,C1orf52,CDC42,DCLK1,ZMYM4,CDH18,CASC2,C7orf61,NRXN3,AKAP6,SLC25A27,COL11A2,SLC4A8,COX4I1,HS3ST5,FAM171B,CLIP3,TRIM69,ARHGEF10,HDAC9,FRMPD4,HDAC4,PITPNC1,ACOT8,YAF2,PHF20L1,RCAN2,KCNMB2,ETV1,RCSD1,F3,TAOK3,GTF2IRD2,HPCAL4,PNMA2,TPPP3,DKK3,ERAP1,FREM1,COPS8,AIFM3,ZNF638,CBX1,INSM2,PLCD4,GRM1,GRM7,ZNF496,LINC00839,RNFT2,IRAK3,RASSF8,HPS5,ZHX1,NCKAP1L,HMGCL,NEGR1,MYLK2,RBPJ,IL6R,IL11RA,LRRTM3,SYT9,BLOC1S2,ADAM22,OCRL,OPHN1,OXTR,PBX1,OLA1,CDK14,CAMKV,A2ML1,RETREG1,ST8SIA5,FTO,HMGCLL1,SPATA6,MED1,CRLS1,PRPH,RELN,PTPRG,PTPRO,ZSCAN2,NWD1,OXR1,RBBP6,RGS4,BAALC,NCBP3,SEMA6D,HOGA1,LINC00461,PRCD,MRAS,ARX,NUBPL,PPP4R3A,DHX30,LRRC55,SLC14A1,BTBD7,SLC22A4,RCOR3,TTC17,TNIK,SYNE2,VPS13A,SYPL1,MTCL1,SEMA4A,DNMBP,ANO4,TEK,MTMR14,ASXL3,KAT6B,ZNF384,ZNF346,ANO5,TTC3,EIF4ENIF1,GORASP1,WNT7A,CLDND1,NDRG4,MKRN3,SLC30A4,ADAMTS9,SLC17A7,WNK3,FAM13C" MicroRNA "TTGCCAA,MIR-182:MSigDB" "TTGCCAA,MIR-182:MSigDB" MSigDB 8.84E-64 4.97E-60 3.37E-63 3.10E-62 111 306 "ADCY2,ADCY6,ADD3,PDZD4,OGT,ANK2,ANK3,ARHGDIA,NUMB,ATP1B3,ATP2A2,ARHGEF7,JAZF1,SEPT7,CDC27,MAGI1,FOXN3,QKI,AKAP7,SLC4A7,BAG4,CLOCK,PREPL,C2CD2,CSNK1E,MYADM,RIMS3,IP6K1,GIT2,ELMO1,RHOBTB1,PLPPR4,DSCAM,DYRK1A,EDNRB,YAF2,MBNL2,EGR3,EIF5,RGS17,EPHB1,SLC43A2,NCALD,FOXF2,FOXO3,KHDRBS3,GABBR1,SEPT9,PCDH17,GK,KDM2B,GRM5,ATOH8,BACH2,KTN1,L1CAM,SMAD1,MARK3,MEF2C,MEIS2,MITF,MMP16,NAP1L1,NKX2-2,NPTX1,NRCAM,OCRL,PC,PCDH8,PCMT1,GPR85,RETREG1,PCDH18,HMGCLL1,PRRX1,PRKACB,PTHLH,RALGDS,RDX,RET,FBXW7,MCMBP,ATAT1,ATXN1,PPM1E,NTNG1,SHC4,SLC1A2,WDR47,PALLD,SOX2,TEX2,NFASC,SYPL1,TACC1,CAMTA1,CAMSAP2,FBXW11,SATB2,DOCK9,RIMBP2,BCL2L13,VAV2,VLDLR,NSD2,EVI5,STOX2,EPM2A,FZD3,RTN4,FXR1" MicroRNA hsa-miR-558:mirSVR_highEffct hsa-miR-558:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.26E-64 5.20E-60 3.52E-63 3.25E-62 153 597 "CLK4,KIDINS220,TBC1D14,AMPD3,PPFIA1,MAGEE2,PPFIA3,RGS20,ARRB2,N4BP2L1,ADAM23,BBS2,ST3GAL5,SYNJ2,OSGIN2,KALRN,CDC42,LGI1,MAGI1,TIGD7,SLIT2,HECTD1,SLC4A8,TCEAL2,CHD1L,SLC35F1,CREM,HAPLN1,PDE4DIP,PLXNA4,ZSCAN23,DCAF4,C2CD2L,TMEM130,DDX46,SNAP91,SPOCK3,G3BP2,SLC29A4,NR1D2,DNM2,DPYSL2,PDCD6IP,DNAJB6,ABCC5,C3orf18,EPB41L2,EPHB1,GMPR2,CLVS1,TOMM40L,FLNC,NOP56,NELFCD,ZCCHC17,ATP2C1,CGREF1,SIGLEC8,WASF3,WASHC2A,SESN1,GK,GLS,LOXL3,DIDO1,ADAMTS13,GRM1,GRM3,AP4S1,GPR45,ATXN2L,SYNPO,KCNC1,KCNH2,KIF5C,TTYH2,SYTL4,NAT8L,ZFYVE27,MAP6,SYT9,MEIS1,MRPL42,PTOV1,MXI1,MYT1,NDUFA5,DNHD1,NPR2,PDE1A,PDE4B,GDAP1L1,ZNF655,XRN1,FTO,EXOSC10,RETREG2,PPP3CB,HYDIN,PROX1,WDR25,PXK,PTPRE,ERI2,UBR7,RGS3,ATP8B4,ADAL,KCNIP1,ASIC4,ELMOD1,KIF21A,ITSN1,LRRC55,SEPHS1,SPHKAP,NAXD,MYO16,ZNF423,NPAS3,ZSCAN29,SEPT8,ADHFE1,STXBP1,SYT5,CAMTA1,ZFP90,RPGRIP1L,RALYL,CYB561A3,ZFPM2,ITGB3BP,LEFTY2,PIK3R5,TPM1,CADM1,MTCH1,RBFOX3,WIPF1,SF1,ZNF23,SLC30A3,CA10,VPS35L,C12orf4,EPM2A,UBE3B,KAT6A,AP3B2,SLC4A10,LAS1L,SENP7,JPH3" MicroRNA "TGCCTTA,MIR-124A:MSigDB" "TGCCTTA,MIR-124A:MSigDB" MSigDB 9.37E-64 5.26E-60 3.56E-63 3.28E-62 142 514 "ABR,TMCC3,PLEKHH1,ESYT2,ZNF608,OSBPL6,SEMA6A,ALCAM,OGT,ANXA7,APBB2,VAT1L,CPNE5,PDXK,TMEM263,IGDCC4,ARHGDIA,CADPS,DPY19L3,RGS9,NRP2,ARHGEF7,JAZF1,WASF1,MYRF,MMD2,CACNB2,PTBP2,MAP7,CACNA2D2,B4GALT6,LHX2,QKI,TMEM184B,CNN3,CNTN1,SLC4A7,MYRIP,SNCAIP,LRIG1,OSBPL3,PLCXD3,ARHGEF4,PPP6R2,KIAA0408,MYADM,HDAC4,TOX,LONRF1,IST1,GIT2,BLOC1S6,SRGAP3,DMD,CDON,E2F6,EDNRB,CELSR3,DCTN4,EN2,ETV1,RTN3,EYA1,PCYOX1,SEMA6C,ANKFY1,TACC2,STAG2,FERMT2,GPM6B,GRIA2,GRID1,RFFL,NR3C1,GRM1,RNF165,BACH2,ELOVL5,NEGR1,ITGA7,KCNK2,KCNQ2,NCOA7,MARK1,MITF,MKLN1,JAKMIP3,NEUROD1,NFIX,CLDN11,KCNK10,CNTN3,PCDH8,CDK18,PDE2A,PDE4A,GPR85,STRN3,PRRX1,FA2H,PPARA,PPP2R5E,MAPK4,PTPRE,RAD17,DUSP15,MORC4,SEC61A2,RAVER2,RYR3,SEMA6D,SCN4B,CASC3,EPN2,ATF7IP,LIMCH1,PALLD,FAM219A,ZCCHC24,SP2,GLT8D1,NFASC,NKAIN2,NXT2,KANK1,TACC1,ATMIN,DICER1,SIRT1,TPD52L2,TRPS1,OSBP2,VSNL1,SMARCAD1,SYNC,PMEPA1,LMAN2L,NAV3,NAV2,MARCH8,PHTF2,ZDHHC20" MicroRNA hsa-miR-454*:mirSVR_lowEffct hsa-miR-454*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-63 5.68E-60 3.84E-63 3.54E-62 179 810 "SDE2,ASIC1,NBAT1,KDM5D,XKR4,CSMD3,ADAR,CCDC85A,BEND6,AP2A2,SPOP,UNC79,MAP4K3,ARHGAP5,ASGR1,STK33,NUMB,ATP1B3,N4BP2L1,RIPK1,BBS2,BCL2L2,DNAJC27-AS1,KSR1,FUBP1,LINC00906,NIPA1,MYRF,LDLRAD4,CA8,PTBP2,TRIM41,CDC42,CCPG1,CFL2,CASC2,KMT2C,CLU,BTF3L4,COX4I1,NRG2,CHD1L,GDA,SEC24C,CST3,EDRF1,DCAF8,RIMS3,KCTD8,MAML1,C8orf34,KIAA0319,FBXO25,RAB39B,RCAN1,ECM2,PHF20L1,GOLGA7,KCTD3,PLEKHA1,ELAVL4,CDHR1,MRPL37,MRPL10,ETV1,ANKMY1,CAP2,RGPD5,ATP13A4,ERGIC3,GPR153,AP4B1,STAG2,BRPF3,NCKAP1,DISC1,KIAA1841,ZNF638,STON1,GPR22,GPR37,STMN2,GRIK2,RABL2A,WIF1,ZHX1,LINC01102,SYNPO,SCIN,KLHL23,KIF5C,LIFR,SMAD9,IL17D,TM6SF1,MEF2C,MEIS1,SCG3,MYO9A,NAP1L1,P2RY13,NCAM2,RCOR2,NOVA1,OPCML,PBX1,PCSK5,PDE4B,PDGFRA,PFKFB3,SNX10,FTO,MTRF1L,PMP2,PRRX1,PPP2R5C,HYDIN,MASP1,SIDT1,PTPN13,FAM120C,OXR1,RBBP6,ZDHHC14,SLC6A15,RET,GSTCD,BAALC,GLDN,LRRK2,ABCA11P,KCNIP2,HOGA1,ASIC4,GALNT10,KIF21A,DOCK10,ST6GAL1,ST3GAL3,ANKRD36,RIMS1,SNAP25,MAPKBP1,MBD5,SNRPN,MYT1L,NMNAT2,PEG10,VPS13A,PLCB1,SYP,CAMTA1,ATMIN,TRIM2,SZT2,DOCK9,TMEM9,TMOD1,TPM1,FNDC5,SSBP2,PLEKHH2,WRN,RICTOR,ZNF28,FMN2,SPHK2,CELF4,REEP1,DPYSL5,UPF3A,WNK1,SLC30A4,EVI5,RNF103,PCDH15,GAL3ST3,CAMK1G,JMJD1C" MicroRNA hsa-miR-2276:mirSVR_highEffct hsa-miR-2276:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-63 5.80E-60 3.92E-63 3.61E-62 177 793 "RALGAPA1,SDE2,ACADM,ASIC2,NCKAP5,ARID1A,AP2A2,MTUS1,SPOP,ARHGAP20,AMPH,DPP10,ALS2,ARNTL,CDK13,DDX3Y,ALDH7A1,ADGRB3,DST,FUBP1,JAZF1,CALB1,TRIM41,CANX,CDC27,MAGI1,ZFYVE9,COG1,MAP4K4,AKAP7,AKAP6,LETMD1,ACBD5,CNRIP1,CREM,PHACTR3,PHF14,CYBB,TCAF1,RIPOR2,MATR3,PABPC5,ZNF804A,C8orf34,FBXL5,PLPPR4,SV2B,NTM,KIF19,DYNC1I1,DMTF1,DPYSL2,ANKRD46,FAM13A,ABI2,COPS4,ELAVL2,DCTN4,COQ7,EYA1,GTF2IRD2,NELFCD,UFM1,STAMBP,ZNF605,ST6GALNAC3,GABRA2,AHCYL1,JPH4,WASF3,GFAP,PCDH17,KIRREL3,RND1,TCERG1,TNRC6A,CBX1,ZNF782,GOLGB1,GPD2,RAPGEF4,GRIA2,GRIN2D,ARHGAP36,HSF2,MSL1,ZNF181,GAREM2,RBPJ,LRRCC1,DIPK1A,IPO5,PAXBP1,NAT8L,MBNL1,MEF2C,LYRM9,NEK1,NF1,SMIM11A,PIRT,DUSP26,XRN1,PLP1,HMGCLL1,EPB41L4B,DRAM2,PKIA,PRKCB,HYDIN,CNTLN,TMEM260,RDX,GTDC1,RGS12,RIT2,ZNF532,EXD2,RPE65,MCMBP,RYR3,SEMA6D,ATXN2,ATXN7,SLC30A10,SELL,CASC3,COPZ1,SGK1,SCG5,ITSN1,SH3GL3,MAGI3,CTXN2,PAAF1,ZNF365,LRRC55,SLC8A1,RAB3GAP1,TET1,CPEB4,SORCS3,SOX1,MYT1L,MYCBP2,KDM4C,DBNDD2,SRPK2,MPRIP,ADHFE1,KANK1,NSFL1C,FGD4,ASTN2,DNMBP,WSCD1,SATB2,ZFP90,ZEB1,DOCK9,SIK3,ITGB3BP,TJP1,FAM124A,CADM1,PITPNB,ZIC1,EMSY,TMEM178A,CAB39L,FAM47E,SLC17A6,C12orf4,RGS7BP,FAM219B,SSPN,SENP7" MicroRNA hsa-miR-138-1*:mirSVR_highEffct hsa-miR-138-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-63 8.72E-60 5.89E-63 5.43E-62 175 778 "BRAP,CDC7,KLHL13,LRRC7,ALCAM,FAM135A,LRCH2,BCAS1,TNRC6C,SHTN1,PRX,PPP4R4,ARNTL,CDK13,CAPRIN2,DDX3Y,CCDC181,SLC4A4,ATP2B1,RNF182,ATP6V0A1,BACH1,MPDZ,DCAF5,BID,CASTOR3,CACNA1D,CALM1,PTBP2,CCNH,MTMR7,INA,AIFM1,SRSF11,PLAA,NMT2,HECTD1,SLC25A27,TOGARAM2,ZFP28,HS3ST5,CHD1L,PREPL,HAPLN1,TRIM69,SNCAIP,SEC24C,OSBPL3,CSNK1G3,ATRNL1,NCAN,DZIP3,CEP170,DDX46,SMG7,DNAH9,DPP6,ABI1,DTNB,FAM78B,DYRK1A,GOLT1B,E2F5,FRY,PHF20L1,EMX2,NRN1,FAM198B,TMEM132C,MED12L,SUCO,CAP2,ATP13A4,FOLH1,C2orf88,UFM1,PHYHIPL,MEGF10,BRPF3,NEU3,USP19,GHR,GLS,ZNF638,GRIA4,PRDM5,KAT7,PSIP1,FRMD5,SMAP1,MSL1,METTL21A,GPR62,KCNJ16,KIT,SFXN5,MDM4,ZNF92,MXI1,NAP1L1,NEUROD1,NFE2L2,NOVA1,OPHN1,P2RY1,GPR137C,GLIPR1L2,SNTG1,PDGFRA,ABCB1,GDAP1L1,XRN1,PURG,PMP22,MAGEL2,PRKACB,BDNF-AS,TMEM260,STK32A,PTX3,TRIM68,RIC8B,SETD5,GSTCD,RPL15,FBXW7,ATP8B4,SFPQ,SUPT20H,NTNG1,SLITRK3,ZNF365,RAB3GAP1,ARHGEF40,BTBD7,TET1,CPEB4,LIMCH1,MBD5,USP33,ERC1,ADHFE1,SYNE2,PLCB1,COBL,MTCL1,CAMSAP2,ALG1,KIAA1107,AGTPBP1,TBCEL,KLHL4,ANO4,SIN3B,CLASP1,PUM2,CSMD1,ZNF384,DCBLD1,ANKRD20A2,SSBP2,CLHC1,CCDC14,TBC1D15,ZNF781,MICU3,KCNT2,LYPD6,FSTL5,FIP1L1,MVB12B,C12orf4,PDSS2,PAK5,JMJD1C" MicroRNA hsa-miR-151-5p:mirSVR_lowEffct hsa-miR-151-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.77E-63 1.56E-59 1.05E-62 9.69E-62 156 625 "NBAT1,CSMD3,AP2A2,TBC1D14,C1QTNF1,SEMA6A,UNC79,AMPH,LRFN1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,CADPS,LINC00173,ASCL1,ATM,CARMIL3,GPR146,KSR1,CALB2,TRIM41,P2RX6,ENTPD6,EVI5L,TIGD7,ASIC3,TAOK2,EPS15L1,NRXN3,PPT2,NIPBL,SMARCAL1,CS,CSF2RA,ZSCAN23,ARMCX4,DCT,ELMO1,MED24,DNM1,HS3ST4,HS3ST2,USP3,DNM2,DNM1L,EDNRA,CACNG7,EGFR,SORBS3,C3orf18,RTN3,TOMM40L,ZNF589,RASL10A,ERGIC3,KHDRBS3,ZNF512,DKK3,ZNF559,IGSF5,SULT1C4,CYP46A1,MMADHC,STARD3,GNAS,TDRKH,LILRA1,GRIA2,ADAMTS13,SERP2,GRIN2D,NR3C1,ZNF496,IL1RAPL1,KAT7,FRMD5,PTGDR2,HLF,FAAP20,MYLK2,IGSF1,ZNF678,INPP5B,KCNC1,MOG,TAGLN3,RTL5,DNHD1,NTRK2,ZNF827,CDK18,ZNF655,EPN1,HMGCLL1,ING3,SEPT4,FA2H,SH3KBP1,RAB39A,MAPK4,MAPK10,PRPSAP2,SIDT1,GDPD2,PIGG,PTCH1,PTPRD,PTPRE,FEZF2,GTDC1,RFX2,ZNF532,ROBO2,STK32B,KCNIP2,RYR3,SARS,LRFN5,SCN3A,MRAS,ITSN1,NTNG1,ST3GAL3,SLC11A1,SLC22A4,SMARCA4,SORCS3,CDK5RAP2,WDTC1,NMNAT2,TAB2,CAMTA2,ITPRID2,TAL1,RPGRIP1L,DOCK9,FRYL,AP4E1,TRPM2,NTSR2,KCNE5,TSC1,TUBB2A,PITPNB,LAT2,ZIC3,ELFN1,PLPP4,PLPPR5,EMSY,PRDM2,DNALI1,CSDE1,SCG2,NAV2,TRAM2-AS1,VANGL2" MicroRNA hsa-miR-320a:TargetScan hsa-miR-320a TargetScan 3.15E-63 1.77E-59 1.19E-62 1.10E-61 153 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,MIER1,CDK13,MYRF,LDLRAD4,CA12,CACNA1E,MAP7,RUNX1T1,KRIT1,FMNL3,CDH2,LRRFIP1,CFL2,CHGA,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,FRMPD4,AIF1L,DBN1,DCC,ARMCX2,ELMSAN1,MYEF2,DLG2,DLX1,RAB39B,DMD,CALN1,DTNA,FAM135B,CELSR3,GPR61,EGR3,PLXNC1,PAN3,EFS,ETV1,NRN1,CACNG2,PRKAG2,MEX3B,FOXM1,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,GABRB1,ILDR2,NCKAP1,ACSS1,DNER,GBX2,ARFIP1,GPR75,KIAA1958,INSM2,GNAL,LOXL3,RFFL,NR3C1,IL1RAPL1,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,KCND3,KCNK1,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,CCDC80,JAKMIP3,MXI1,NFIA,CNOT4,GPR88,P2RX7,PBX1,PCSK1,PDE3B,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,RIMKLA,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,LRRC4,NXT2,NCDN,MAPK8IP3,ATP11A,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320b:TargetScan hsa-miR-320b TargetScan 3.15E-63 1.77E-59 1.19E-62 1.10E-61 153 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,MIER1,CDK13,MYRF,LDLRAD4,CA12,CACNA1E,MAP7,RUNX1T1,KRIT1,FMNL3,CDH2,LRRFIP1,CFL2,CHGA,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,FRMPD4,AIF1L,DBN1,DCC,ARMCX2,ELMSAN1,MYEF2,DLG2,DLX1,RAB39B,DMD,CALN1,DTNA,FAM135B,CELSR3,GPR61,EGR3,PLXNC1,PAN3,EFS,ETV1,NRN1,CACNG2,PRKAG2,MEX3B,FOXM1,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,GABRB1,ILDR2,NCKAP1,ACSS1,DNER,GBX2,ARFIP1,GPR75,KIAA1958,INSM2,GNAL,LOXL3,RFFL,NR3C1,IL1RAPL1,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,KCND3,KCNK1,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,CCDC80,JAKMIP3,MXI1,NFIA,CNOT4,GPR88,P2RX7,PBX1,PCSK1,PDE3B,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,RIMKLA,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,LRRC4,NXT2,NCDN,MAPK8IP3,ATP11A,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320d:TargetScan hsa-miR-320d TargetScan 3.15E-63 1.77E-59 1.19E-62 1.10E-61 153 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,MIER1,CDK13,MYRF,LDLRAD4,CA12,CACNA1E,MAP7,RUNX1T1,KRIT1,FMNL3,CDH2,LRRFIP1,CFL2,CHGA,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,FRMPD4,AIF1L,DBN1,DCC,ARMCX2,ELMSAN1,MYEF2,DLG2,DLX1,RAB39B,DMD,CALN1,DTNA,FAM135B,CELSR3,GPR61,EGR3,PLXNC1,PAN3,EFS,ETV1,NRN1,CACNG2,PRKAG2,MEX3B,FOXM1,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,GABRB1,ILDR2,NCKAP1,ACSS1,DNER,GBX2,ARFIP1,GPR75,KIAA1958,INSM2,GNAL,LOXL3,RFFL,NR3C1,IL1RAPL1,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,KCND3,KCNK1,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,CCDC80,JAKMIP3,MXI1,NFIA,CNOT4,GPR88,P2RX7,PBX1,PCSK1,PDE3B,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,RIMKLA,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,LRRC4,NXT2,NCDN,MAPK8IP3,ATP11A,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-320c:TargetScan hsa-miR-320c TargetScan 3.15E-63 1.77E-59 1.19E-62 1.10E-61 153 602 "C3orf14,NDRG3,RNF150,PTCHD1,PCDH19,KIAA1324,APBB2,MIER1,CDK13,MYRF,LDLRAD4,CA12,CACNA1E,MAP7,RUNX1T1,KRIT1,FMNL3,CDH2,LRRFIP1,CFL2,CHGA,ENTPD4,HAPLN1,ABCG1,OSBPL3,RIMS4,PPP1R16B,FRMPD4,AIF1L,DBN1,DCC,ARMCX2,ELMSAN1,MYEF2,DLG2,DLX1,RAB39B,DMD,CALN1,DTNA,FAM135B,CELSR3,GPR61,EGR3,PLXNC1,PAN3,EFS,ETV1,NRN1,CACNG2,PRKAG2,MEX3B,FOXM1,FLNC,ANKFY1,FAM49B,FUT9,MSANTD4,GABRB1,ILDR2,NCKAP1,ACSS1,DNER,GBX2,ARFIP1,GPR75,KIAA1958,INSM2,GNAL,LOXL3,RFFL,NR3C1,IL1RAPL1,BVES,RASSF8,MIER3,NEGR1,AGFG1,MSL1,IL6R,CDH20,KCND3,KCNK1,IPO5,HECTD2,MAT2A,MBD1,CHIC1,MEIS2,KITLG,MITF,MMP16,MN1,DBNL,CCDC80,JAKMIP3,MXI1,NFIA,CNOT4,GPR88,P2RX7,PBX1,PCSK1,PDE3B,PDE4D,PFKFB3,PIK3R1,PPP2R2C,PRKAB2,CEP41,CNNM2,BCAS3,PTPRB,PRRT2,MORC4,ALG9,RPL15,RIMKLA,HUNK,RXRA,CSRNP3,CNKSR2,EPN2,DHX30,EPC1,LMO3,LRRC4,NXT2,NCDN,MAPK8IP3,ATP11A,FAM208A,MGRN1,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CHST8,HEY1,KAT6B,DOK6,NR2C2,EVI5,PPP1R3F,KCNAB1,FZD3,FXR1,LAS1L" MicroRNA hsa-miR-3152:mirSVR_highEffct hsa-miR-3152:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.58E-63 2.01E-59 1.35E-62 1.25E-61 161 666 "TTYH1,ASPHD1,XKR4,LRFN2,BEND6,SPARCL1,DPP10,ANK2,ANK3,ARNTL,ASPH,ATP1A2,STX16,ATP2A2,ZNF582,LINC00847,OSGIN2,CALM1,CAST,BRSK2,MTMR7,CD81,SEPT7,CDC27,CHGA,SOCS6,KIAA1549L,MAP4K4,TMEM155,FHL5,ARMC8,AKAP6,AHCTF1,ANKRD44,TRIM69,TENM4,ARHGEF10,PHACTR3,PNPLA8,HDAC9,HP1BP3,DYNC1I1,CPEB2,DRD1,ACOT8,DTNA,ECM2,DNAJB6,E2F5,CNNM1,FSD1L,YAF2,GOLGA7,EIF4G2,EMX2,OLIG2,KCNMB2,IGSF6,FAM198B,RPS6KC1,EFEMP1,GORAB,GTF2IRD2,FHL1,SUCO,SLC37A3,STAMBP,STAU2,B3GAT1,FYB1,GABRA1,FAM184B,GALC,SIGLEC8,ARFIP1,CYP46A1,KIAA1958,WDFY3-AS2,FUT10,RNFT2,ADAMTS6,WIF1,HNRNPK,HSF2,RBPJ,USP54,IGSF1,LIX1,TUBB2B,LRRTM3,KCNJ10,KCNN2,SFXN5,VWA5A,MAP2,MARK1,MBNL1,SYT9,FXYD6,NF1,CLDN11,PBX1,CYTL1,CCSER2,PPP2R5C,PPP2R5E,SAMD9,GON4L,MTMR10,PTPRD,PTPRE,ZNF615,RDX,ZYG11B,SETD5,RPE,NEK11,LRRK2,ABCA11P,ATAT1,AMER2,LRRTM4,SCN8A,TNFRSF19,CPEB3,SORCS3,RIMS1,SNAP25,KIF13A,TRERF1,TNIK,KIF1B,PBLD,COLGALT2,NKAIN2,NXT2,DIP2A,SYT1,C12orf76,TAC1,CAMTA1,ALG1,SIN3B,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEX15,FAM200B,C18orf54,C5orf64,FAM155A,MTCH1,PLPPR5,PRDM10,ADAMTSL3,TIGD6,SNX14" MicroRNA hsa-miR-148a:PITA hsa-miR-148a:PITA_TOP PITA 4.19E-63 2.36E-59 1.58E-62 1.46E-61 137 483 "ASIC1,ADCY2,CCDC85A,HECW2,ALCAM,PCDH10,PITPNM2,OGT,APBB1,MIER1,MARCH3,NCOA1,MTMR9,NOL4,ADGRB3,BCL7A,CDK5R1,SYNJ1,BSN,CACNB2,CALM1,CAMK2A,CANX,USP6,MAGI1,NOG,CFL2,SRSF11,PLAA,CLCN3,QKI,CNR1,ARMC8,CLOCK,ST18,RUBCN,SNAP91,DLG2,RAB39B,DMPK,DYRK1A,ST8SIA3,KLHL5,FRY,EGR3,ELAVL2,EPB41L1,SLC43A2,RTN3,EZH1,SCML2,ATP8A1,MED12L,PRKAG2,NPTN,GAP43,C15orf41,DNER,ARFIP1,WASHC2A,AHDC1,PPARGC1A,SPIN1,TNRC6A,KDM2B,LOXL3,GPM6A,PCLO,TPPP,BACH2,HLF,AGFG1,IGF1,C5orf24,KIT,STXBP5,MITF,NCAM1,NDP,NEUROD1,NFIX,NPTX1,NUMA1,OPA1,GPR137C,PDE1C,PDE4B,PDE4D,CDK14,PIK3C2A,ANKRD16,POU3F2,MED1,KANSL1,MTMR10,PTPRD,FAM184A,ROBO1,ROBO2,RORB,ATXN1,SCN2B,PPP1R9A,CHD9,FBXO11,BTBD3,WDR47,SLC8A1,CPEB4,SOX11,CDK19,SRPK2,PLCB1,SYT1,SYT4,ATP11A,TCF4,ARHGEF12,FRYL,DICER1,ZFPM2,AP4E1,AKTIP,MTMR14,TNFRSF1B,RBFOX2,TRPS1,CADM1,BEST1,TMEM237,SLC38A1,SNX27,RTN4,KAT6A,CERS6,FXR1,JPH3" MicroRNA hsa-miR-1294:mirSVR_highEffct hsa-miR-1294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.77E-63 2.68E-59 1.80E-62 1.66E-61 174 775 "VWA5B2,ARID1A,KLHL32,BRAP,ADRB2,UNC79,PITPNM2,AMT,LRCH2,FGD2,PHYHD1,TMEM263,SPTBN4,ARRB2,ASTN1,ATP1B3,N4BP2L1,TTLL9,SEC11C,ARHGEF7,GYG2,SGCE,CACNA1B,KALRN,CAST,CCKBR,CDH10,LGI1,TIGD7,CHN2,EPS15L1,PLAA,TPP1,ARMC8,FAM149A,SLC4A8,AKAP12,SNCAIP,SEC24C,PDE4DIP,DZIP3,ST18,HDAC9,KATNAL2,ARHGAP24,KIAA0513,LONRF1,LIN54,IST1,DGKG,MYEF2,SV2B,SPOCK3,CHRDL1,DMD,DTNA,AASDH,EDN1,EDNRB,OPTN,STARD3NL,C8orf37,EIF1,LRRC17,ADGRV1,FCGR1A,TMEM107,KHDRBS3,DISC1,ACSS1,GART,LRRC37A6P,GCNT2,TTBK1,COPS8,ZNF782,CNTRL,DIDO1,ADAMTS8,LINGO1,HAS2,DDX19B,ARHGAP36,ACOT7,MSL1,IGSF1,IL6ST,KCNC1,CREG2,HECTD2,NCOA7,MAN2A2,MAT2A,MMP16,WDR49,MOBP,ZNF680,MSR1,CTNNA3,MXI1,MYO9A,NAP1L1,NEFM,NF1,NNAT,NPPA,NTRK3,OPRL1,ZNF827,PAK3,HERC2P3,NLGN3,FTO,PLP1,PMP2,PRRX1,EPB41L4B,GRAMD1C,PRPSAP2,MDGA2,PTPRG,FAM120C,CEP97,NWD1,RADX,KHDRBS2,MSANTD2,RDX,ZYG11B,GTDC1,FIGN,RGS3,KCTD17,ARHGEF10L,RAVER2,GSTCD,ROBO1,ROM1,CCDC102B,EPHA10,ATP8B4,ATAT1,SEC14L1,TRIM46,MAGI3,FHOD3,SCMH1,RCOR3,RIMS1,SOX2,KIF1B,CLSTN2,SULF2,SYP,SYT4,TRIM2,WASHC4,CLASP1,DICER1,GZF1,MTMR14,C5orf64,RBFOX2,PRMT8,MEAF6,TBC1D15,RBFOX3,PLPPR5,CA10,PRDM2,ADAMTS9,UBE3B,VANGL2,NETO1" MicroRNA hsa-miR-93*:mirSVR_highEffct hsa-miR-93*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.92E-63 2.76E-59 1.86E-62 1.71E-61 197 978 "TTYH1,NBAT1,ACTN2,ARID1A,NDRG3,KLHL32,ADD3,NLGN4X,OGT,ANK3,SUGT1P4-STRA6LP-CCDC180,CACHD1,TNRC6C,MIER1,CAPRIN2,ASTN1,SLC4A4,N4BP2L1,SEC11C,SYNJ1,ARHGEF7,CACNA1E,CACNB2,PTBP2,RUNX1T1,AIFM1,SCARB1,TIGD7,CHGA,SYNPR,MYL6B,NGEF,DNAJB5,TMEM155,COL11A2,AKAP5,CPS1,GALNT9,PPP1R16B,UBXN2A,CTNND2,DOCK4,FGFR1OP2,DCAF8,EARS2,TOMM20,DDX46,SPOCK3,DLG2,USP3,NR1D2,CPEB2,EDN1,ATL1,ANKRD46,MBNL2,KMT5B,PLEKHA1,PAN3,EPHB1,DNAJC27,NRN1,FCGR1A,FER,SUCO,IQCG,NOP56,NELFCD,ZCCHC17,STAMBP,ERGIC3,GAD1,ALDH1L1,SESN1,GK,ZNF276,MSL3,ZNF638,STON1,GRIA2,GRIA4,FAM19A2,SLC2A6,CELF3,KLF12,MIER3,IL6ST,ZNF678,KCND2,KCNJ10,KCNK2,STXBP5,HECTD2,PACRG,MBP,MDM4,MEIS1,MOBP,MYCN,NAP1L1,NEUROD1,NF1,DNHD1,NTRK2,TBC1D25,CNTN3,PCSK1,PCSK5,CDK18,GPR85,OLA1,NALCN,A2ML1,STRN3,ING3,MBOAT7,SH3KBP1,PPM1B,SIDT1,SNRK,PTHLH,PTPRB,CEP97,TMEM255A,RAD17,CCDC40,RASGRF2,ARID4A,RBBP6,ZYG11B,MORC4,NUDT11,NEK11,ATAT1,SEMA6D,SUPT20H,NLGN4Y,ITSN1,ASAP3,NTNG1,DZIP1,PREX2,SEPHS1,RAB3GAP1,BTBD7,NAXD,GKAP1,OGDHL,SORCS3,MYH15,SMARCE1,ANKRD36,SNCA,SNRPN,UNC80,USP33,DOP1A,TRERF1,SOX5,BDP1,ZSWIM8,GLT8D1,KDM4C,ZC3H13,PBLD,SSTR1,RGL1,PHLDB1,NECAB1,FGD4,NUDT10,COBL,SYT5,DDHD2,ZEB1,FRYL,SIRT1,ZMAT3,TLR4,TMPO,TNS1,SYNPO2,ZMYND8,DCBLD1,KCNE5,SGK3,RICTOR,XRCC4,ZFP37,ZIC3,ZNF189,ANKS1B,PLPPR5,CADM2,UBE3B,ZNF248,LAS1L" MicroRNA hsa-miR-99a*:mirSVR_lowEffct hsa-miR-99a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.28E-63 3.53E-59 2.37E-62 2.18E-61 146 551 "CLK4,NCKAP5,GRAMD1B,PWWP2A,FAHD2CP,GPR158,CC2D2A,SRPX,CARNS1,SUGT1P4-STRA6LP-CCDC180,UPRT,API5,CDK10,TMEFF1,PDE8B,ZBTB10,SNAI3-AS1,BARD1,BCHE,RAB29,KALRN,PTBP2,TRIM41,L3MBTL4,JAM2,LHX2,WHRN,COL9A1,HS3ST5,CSNK1E,OSBPL3,SOCS5,RASGEF1C,PUM1,CYBB,KCTD8,SCRN1,ZEB2,MED12,DNM1L,EDN3,HIPK3,ELAVL2,ANKRD13B,SRRM1,TAOK3,ZNF589,PRKAG2,SORBS1,APOPT1,STAMBP,STAU2,STAG2,CHL1,TRAF3IP2,HBS1L,FAM120B,GALR1,CPLX1,GGT7,GLYR1,ZNF638,GRID1,GRM7,CLASRP,HLF,HMGB1,AGBL5,HP,HPR,LINC00667,IL6R,ZNF385B,KCNJ10,KCNN3,KIT,C2orf80,LOC100128239,MSR1,CTNNA3,LYRM9,FXYD7,NCAM2,NELL2,NF1,NOVA1,NUCB2,OMG,PCMT1,PDE4A,ENPP2,PDYN,HERC2P3,JAKMIP1,RC3H2,EPB41L4B,FA2H,MAPK4,VPS13C,CNTLN,TMEM260,TRIM68,FIGN,SEC61A2,RPRD1A,RAVER2,SCP2,HSPA4L,SCG5,ITSN1,ARX,CPEB3,CHD9,FNDC3A,EPN2,PKNOX2,SNRPN,KIF1B,PBLD,ITPRID2,THSD1,PRRC2C,CAMTA1,TAL1,VWC2,TPCN2,TRIM2,SYNE1,DOCK9,CCDC173,R3HDM1,SSBP2,MEAF6,CCDC14,CLIP2,GPR158-AS1,CSDE1,VPS35L,SEMA3B,PPP1R3F,KCNAB1,KAT6A,PHTF2,ZNF248,SOCS4,JPH3" MicroRNA hsa-miR-423-5p:mirSVR_highEffct hsa-miR-423-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.88E-63 3.87E-59 2.59E-62 2.39E-61 162 677 "TTYH1,ACLY,SYS1,ARID1A,SLC12A5,ERMN,ADRA1B,DPY19L2P4,AP2A1,ZNF608,KIAA1324,SPOP,FAM135A,ARRB2,CDK13,ATP6V1G2,ADAM15,BTK,KALRN,USP2,INA,CDC42,CPNE6,PPT2,CLCN4,CLTB,FADS2,TMEM155,SLC25A27,LETMD1,CLIP3,AATK,FEZ1,MICAL2,PDE4DIP,ECE2,ZNF337,DGKB,DBI,SPATA2,DCTN1,HEPH,CNIH3,MAGI2,LYPD1,DDX46,G3BP2,TMCC2,ATN1,MAMLD1,DYRK1A,FIS1,FCF1,EFNA3,YAF2,EGFR,USPL1,EIF1,EPHB1,RAB9B,DUSP27,SIRPB1,EZH1,PTK2B,FCGR1A,FGFR3,SUCO,AGAP3,FOXM1,PDLIM5,CGREF1,CHL1,B4GALNT1,ERAP1,LRRC37A6P,GLYR1,GLUL,POLL,STON1,RFFL,GRIN2D,GRM1,AP4S1,NXPH3,HSPA1L,MSL1,INPP5B,KCNC1,KCND2,KCNQ3,MAT2A,MDM4,MN1,BCO1,MT3,TAGLN3,NNAT,SLC11A2,NRCAM,NTRK3,OGDH,PCSK1,PDYN,GPR173,ZNF655,PLTP,EPB41L4B,PPARA,TMEM235,PKIA,BCAS3,SIDT1,CNTLN,TMEM260,PTPRB,PYGM,PRRT2,YY1AP1,SPIN3,ST6GALNAC6,RTKN,SCP2,TRIM46,SELL,ITSN1,FERMT1,HKDC1,AMBRA1,SLC4A3,SLC14A1,SLC20A2,SLC22A4,CDK5RAP2,KDM4C,ERC1,C11orf87,ATP10B,RGL1,STXBP1,PLCB1,SMG6,TCF12,SYNE1,NAT16,OBSL1,USP32P1,RELL2,PRRT1,R3HDM1,METTL3,DCBLD1,SSBP2,RPRM,OSBP2,ZNF177,EML6,SYNC,ZNF225,DNALI1,HPS4,CASC15,MSRB3" MicroRNA hsa-miR-3144-3p:mirSVR_highEffct hsa-miR-3144-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-63 4.22E-59 2.83E-62 2.61E-61 191 926 "CSMD3,KLHL32,SORCS1,SLC44A5,GPR158,CASKIN1,WDR35,TAOK1,LRRC7,ALCAM,OGT,PKP4,ALS2,PPP4R4,ARNTL,ZBTB10,ASTN1,INSYN2B,EIF4G3,CACNA1E,RUNX1T1,NFS1,TMEM257,LRBA,CFL2,CHM,NRXN1,FHL5,AKAP6,AKAP5,ABI3BP,COX4I1,TOGARAM2,MYRIP,ZNF521,MFSD4A,GDA,KIAA0040,UBXN2A,NRSN1,RIMS2,ST18,EDRF1,HDAC4,SCRN1,C8orf34,MYEF2,COPS7A,MAGI2,SACS,G3BP2,RABGAP1L,NR1D2,DPP6,PDCD6IP,ARRDC4,GOLT1B,EDN3,FRY,SH3GLB1,EGFR,GOLGA7,RCAN2,EPHA5,RABEPK,CEP85L,ETV1,CEND1,EYA1,ACSL4,DLC1,RACK1,FER,KIAA1109,FGFR1,SGIP1,STAU2,STAG2,GABRA1,GAD1,ERAP1,DNER,TNRC6A,LOXL3,GPD2,ATF7,LPAR4,CECR2,GRID1,SOX21,NEGR1,SMAP1,KCNJ16,KLRC2,LAMP2,AQP11,MDM4,MEF2C,SCG3,NAP1L2,GPR88,CLDN11,P2RY1,GLIPR1L2,SNTG1,PBX1,NALCN,PMP2,RC3H2,ING3,PACSIN1,PPP2R5E,PRKACB,DCHS2,OCIAD1,PEX2,TMEM231,USP47,RAP1GDS1,OXR1,RDX,GTDC1,RGS12,ZFHX4,SETD5,CARF,YY1AP1,ATP8B4,CNTNAP3,HUNK,NCBP3,TRAPPC13,SALL1,SCN2A,SLC30A10,SH3GL2,SH3GL3,CPEB3,NTNG1,HKDC1,CNKSR2,NLGN1,SLC1A7,DHX30,ATF7IP,MYH15,SNCA,BDP1,DBNDD2,SRPK2,ATP10B,LARP4,SYP,SYPL1,MTCL1,DDHD2,TCEA1,SATB2,TCF7L2,SYNE1,NSD1,DICER1-AS1,AP4E1,TLL2,NPL,SMUG1,RUNDC3B,STXBP4,TRPC1,CLHC1,FLRT2,WIPF1,NSD2,RICTOR,GUSBP1,PCDH20,TCEAL7,ZBTB16,AMZ1,ZFAND5,EMSY,MFF,PRTFDC1,PCDH15,FIP1L1,CAB39L,FAM47E,PARP11,RGS7BP,MRPL47,RNF170" MicroRNA hsa-miR-92a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.48E-63 4.76E-59 3.19E-62 2.94E-61 241 1407 "ACLY,RBM10,ARID1A,NDRG3,TMCC3,SLC12A5,GRAMD1B,USP31,CASKIN1,OSBPL8,CC2D2A,AK2,FAM135A,ZNF687,OGT,USP28,PHF12,PDXK,ARHGDIA,ARRB1,DYNLL1,ATM,ATP1A1,CCDC181,ATP2A2,KIF1A,BCS1L,BID,CDK5R1,SYNJ1,BTRC,CARS,HIP1R,PRC1,ARHGEF25,CBR1,CBS,CBFA2T2,SCARB1,CDC27,CHN1,PLEKHB1,SYNPR,TAOK2,NRXN3,CLTA,CLTC,TMEM184B,HECTD1,COX4I1,LRIG1,SIPA1L1,SOCS5,PDE4DIP,APPL1,PPP6R2,EDRF1,ZFYVE16,EARS2,MAML1,SPOCK2,GIT2,DBT,MYEF2,HP1BP3,KLHL3,SV2A,G3BP2,DNM2,CPEB2,PDCD6IP,RCAN1,DYRK1A,HIPK3,OPTN,MRO,KMT5B,EIF4G2,PLEKHA1,EIF1,DNAJC27,TUBB3,SCML2,KIAA1109,SLC37A3,FLYWCH1,NPTN,CSPG5,SARAF,DOT1L,GAA,AHCYL1,NEK6,ERAP1,ZNF276,RNPS1,GLYR1,MSL3,KIAA1958,PRRC2B,FUT10,LILRA2,TUBA1C,TPPP,DIDO1,RFFL,CACFD1,CIT,SLC2A6,ATXN2L,HMGB1,GABARAPL2,HMGCR,AGBL5,EID2B,C5orf24,ZIC5,RBPJ,IGSF1,IL6ST,TUBB2B,KCNC1,IPO5,LAMP2,PIK3AP1,MAP4,MBNL1,SHC3,MEF2C,AFDN,SESN3,MYO5A,MYO6,HNRNPM,NDUFA5,CNOT4,NUCB1,CAMKV,PIK3CD,CCSER2,SNX10,ZFYVE21,XRN1,PKM,NLE1,PURG,TATDN3,MAPK8,MAPK9,UHRF1BP1,MTMR10,PTPN13,CEP97,ATG16L1,REV3L,TTLL7,KLHL11,SLC25A36,ZFHX4,RNH1,SETD5,RPL15,FBXW7,TRAPPC13,SAFB,ATXN1,ATXN7,HOGA1,FNIP1,SEC14L1,RASA3,SCAF8,CPEB3,SHMT2,WDR37,DHX30,KANSL3,SLC6A8,ZNF430,SLC12A4,BTBD7,ATF7IP,CPEB4,FAM126B,SOX11,MYCBP2,KIF1B,MCF2L2,PBLD,CAMTA2,POGZ,ITPRID2,EPB41L3,NCDN,GANAB,NSFL1C,JMJD6,SUPT5H,ATP11A,TACC1,TBCEL,TBL1X,EHBP1,SIN3B,DOCK9,AHCYL2,SIRT1,MTMR14,NACC2,CBX5,RBFOX2,TPM3,TRIO,ZMYND8,TSC1,HSPBP1,SGK3,UBE2H,UCHL1,SLAIN1,NSD2,KLC2,CLDND1,XPO1,ZNF17,ZNF24,FTSJ1,PMEPA1,MFF,CSDE1,EVI5,GDPD5,XKR7,RNF103,WIPF2,PHTF2,RSPRY1,VANGL2,NHSL1,FXR1,GAN" MicroRNA hsa-miR-1271:PITA hsa-miR-1271:PITA_TOP PITA 9.97E-63 5.60E-59 3.75E-62 3.45E-61 118 356 "ABAT,XKR4,SLC25A25,ADCY6,SLC12A5,SNX30,SLC24A4,LRRC7,SEMA6A,ALK,OGT,LRCH2,C6orf89,BRINP2,B3GALT2,DPY19L3,ADGRB3,MTMR3,JAZF1,CACNA1G,NIPA1,CDK5R2,LDLRAD4,CACNB4,THSD7A,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,NRXN1,CLTC,MAP4K4,NIPBL,CNN3,CABP1,MYRIP,CDC42BPB,LRIG1,RIMS4,ERC2,CTNND1,ARHGAP24,FRMPD4,TM9SF4,C8orf34,CEP170,E2F5,SNX29,EIF5,GPHN,FOXF2,FAM49B,ST6GALNAC3,FYN,BRPF3,B4GALNT1,PCDH17,SPIN1,GPM6A,RAPGEF4,GRIA1,GRID1,GRM1,GRM7,ZHX1,MBNL1,CHIC1,MITF,NEXMIF,NOVA1,IGSF11,GPR85,PIK3C2A,ANLN,EPB41L4B,SH3KBP1,MED1,ATG16L1,BSDC1,ZFHX4,MCMBP,ATXN1,SOX6,TRIM46,MRAS,MAGI3,FAM81A,PPP4R3A,BTBD3,CPEB4,MYO16,SOX5,RAP1GAP2,EPB41L3,LRRC4,SS18,KLHL7,COBL,TAC1,TACC1,CAMTA1,FBXW11,TBL1X,TBX15,TCF4,SIN3B,ARHGEF12,ZIC2,ZIC3,TMEM198,ZFAND5,PMEPA1,NAV3,ST7,JMJD1C,SLC4A10,GAN" MicroRNA hsa-miR-610:mirSVR_highEffct hsa-miR-610:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.18E-62 6.63E-59 4.44E-62 4.09E-61 165 704 "ACADM,ADD3,ESYT2,SLC44A5,HACE1,LCORL,SUGT1P4-STRA6LP-CCDC180,APC,UPRT,CACHD1,MARCH3,DDX3Y,ATP2A2,ATP2B1,BMP7,ST3GAL5,KALRN,RUNX1T1,CBR1,TMEM257,CDC42,NUMBL,MS4A7,NDST3,TJP2,FAM19A5,CNTN1,COL4A5,SLC4A8,SMARCAL1,HINFP,ANKRD44,GDA,CSNK1G3,PUM1,LIN54,DGKB,PABPC5,DBN1,ZEB2,FBXL5,MAGI2,ALKBH8,SMG7,DMD,EBF1,FCF1,RASGRP1,FSD1L,PLEKHA1,PAN3,SRRM1,DENND4A,MRPL37,MRVI1,HSPA12B,F3,FABP7,DLC1,SLC9B2,FGF14,FGFR1,SUCO,JKAMP,NPTN,NSG1,MSANTD4,SARAF,TBR1,AP4B1,OGA,GABRA2,ERAP1,MALT1,MAP7D2,GRM5,GRM8,CIT,GUCY1B1,RASSF8,ELOVL5,HNF4G,PLD5,SCIN,INPP5B,KCNC1,CREG2,INSYN2,SMAD1,PIK3AP1,MEIS1,KITLG,XRRA1,COL28A1,NFE2L2,NUCB2,ETFRF1,PCMT1,PDE4D,PDGFRA,MTRF1L,PRIMPOL,MBOAT7,RASGEF1B,MAPK9,GRAMD1C,VPS13C,MDGA2,QRICH1,PIGG,CNTLN,PTHLH,PTPRD,ACSM5,MARCH1,RET,RGR,RNF220,RPRD1A,LGI2,ROBO2,KCNIP2,SAFB,SCP2,SOX6,RASA3,SHC4,ST3GAL3,ABLIM3,SLC12A2,SLC15A2,SMARCE1,RCOR3,SNRPN,PALLD,USP33,NMNAT2,SRPK2,NKAIN2,STXBP1,KLHL7,NECAB1,SYT11,FAM208A,TCEA1,ZFP90,TJP1,TLR4,TMPO,CSMD1,KAT6B,TPM3,TRPC3,ANKRD20A2,HEPACAM,SLAIN1,CCDC14,CLDND1,CFAP298,DHX33,WNK3,RGS7BP,PHTF2,NLRP3,NETO2" MicroRNA hsa-miR-500b:mirSVR_highEffct hsa-miR-500b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-62 7.97E-59 5.33E-62 4.90E-61 155 624 "ACADM,SYS1,NLGN4X,ANK3,ALS2,AQP4,ALDH4A1,ATP1B3,NOL4,ADAM23,LINC00847,CFLAR,CASTOR3,CALB2,CAMK2B,CAST,USP6,LRBA,CLGN,COPB2,NRXN3,TPP1,NMT2,AKAP6,RBM39,RNF14,UBXN2A,ZFYVE16,KIAA0586,PITPNC1,ZEB2,KIAA0753,RABGAP1L,DNM1,USP3,DNM2,CASP8AP2,ACOT8,PDCD6IP,ABCC9,WDPCP,KLHL5,APH1A,CEP85L,ADGRV1,F8,CORO2B,SEC23B,SGIP1,ZNF605,NRG3,RAPGEF6,C15orf41,ADAM28,TXNL4A,COPS8,DBF4,KDM2B,KCNMB4,RFFL,GSTT2,RASSF8,MIER3,HNMT,USP51,HSP90AA1,SMAP1,IGF1,SCIN,JAK2,SLC35G1,KCNH2,KCNMA1,IPO5,HECTD2,MMP16,ERICH3,ADAM22,RSPO2,CNOT4,GPR88,PCSK5,PDCD2,PLCD1,JAKMIP1,PLP1,PRIMPOL,STRN3,PILRA,PPM1B,PRKACB,EPDR1,HYDIN,PSMD13,CNTLN,BDNF-AS,PTHLH,TMEM260,OCIAD1,PTPRD,PTPRE,CEP97,REV3L,RFX4,SEC61A2,SLC25A36,SETD5,ARMC5,CCDC102B,RPE,BAALC,ATAT1,RMI1,SATB1,LRRTM4,CASC3,ITSN1,ST6GAL1,PAAF1,ZNF365,SEPHS1,ANKRD36,MBD5,ZNF415,SNRPN,KDM4B,USP33,NKAIN2,STXBP1,NUDT10,TACR1,MTCL1,ANO4,ATMIN,TCEA1,AKNA,FRYL,C18orf54,TLR4,ERCC6L2,C5orf64,CDK20,RUNDC3B,TUBB1,UGT8,ZNF709,PCDH20,MICU3,KCNT2,LYPD6,CELF4,SYNC,SLC17A7,FBXO36,ADAMTSL3" MicroRNA hsa-miR-410-3p:TargetScan hsa-miR-410-3p TargetScan 1.61E-62 9.04E-59 6.04E-62 5.56E-61 129 431 "C3orf14,FMNL2,ELFN2,ADD2,GRAMD1B,RNF150,KCTD16,HACE1,LCORL,PARG,CNTNAP1,APAF1,MIER1,CASK,ARHGAP5,CDK13,PDE8B,NUMB,ATP2B2,DCAF5,CALM1,KRIT1,CCNT1,DGKI,CFL2,NRXN3,FAM19A5,QKI,IQCK,ARMC8,BTF3L4,AHCTF1,CREB5,HAPLN1,CSF1,OSBPL3,CTNND1,ARHGAP24,FRMPD4,MATR3,IP6K1,MFAP3L,DLG3,CALN1,CDON,DPYSL2,ATN1,DTNA,KLHL5,EFNA2,PLXNC1,ELAVL4,RGS17,EPS8,FGFR3,PSD2,MPP6,GAB1,RAPGEF6,ARFIP1,GLRB,LOXL3,PRRC2B,PRUNE2,NUDT21,GRIA2,PARD3B,NR3C1,IL1RAPL1,GUCY1A2,RASSF8,KLF12,HLF,HMGB1,HTR2A,IGF1,ITPKB,KCNJ3,KIT,LSAMP,SCAMP5,AFF1,MMP16,CD200,NPTX2,HCN1,PCDH8,PCSK5,PDE3A,PDPK1,CDK14,PRRX1,PTPRB,CEP97,ATG16L1,BSDC1,RDX,PRIMA1,PBRM1,RORB,MCMBP,SCN2B,HSPA4L,PPP1R9A,CPEB3,MAGI3,ABLIM3,ARHGEF40,ELMO2,CPEB4,MBD5,PDZD2,KDM3A,CDK19,C11orf87,POGZ,LRRC4,C3orf70,ATP11A,ANKRD12,RGMB,RFTN2,FRRS1L,PMEPA1,MAP3K12,PPP1R3F,KAT6A,HNRNPA3,NETO1" MicroRNA hsa-miR-196b:mirSVR_highEffct hsa-miR-196b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.61E-62 9.04E-59 6.04E-62 5.56E-61 167 722 "FAM43B,BRAP,SORCS1,ERMN,MAP4K3,APAF1,UPRT,TNRC6C,MIER1,ARNTL,RASL11B,ATP1A2,ATP2A2,DOCK11,RAB29,CACNA1E,CACNB2,CALM1,PTBP2,CDC27,CDH18,CCPG1,PPT2,FAM19A5,QKI,MAP4K4,FAM149A,AKAP6,ABI3BP,TBPL1,CHD1L,TRIM69,ATRNL1,DZIP3,CTNND1,PPP6R2,CYBB,BOC,HDAC9,GPRASP1,KIAA0586,HP1BP3,KLHL3,SMG7,SNAP91,RAB39B,EDNRB,MBNL2,ELAVL4,EPB41L2,LRRC17,WAC,EFEMP1,ZSCAN30,SLC9B2,GTF2IRD2,FHL1,RGPD5,ANKFY1,C2orf88,ATP2C1,SARAF,ZNF512,FYB1,GABRA2,GABRA3,GABRB3,ZMYND11,GALC,DISC1,DNER,NEU3,GHR,TOX3,GPM6B,GRIA2,PRDM5,RNF165,TMEM25,PSIP1,DDX19B,ZNF385B,NME9,KCNJ10,MBNL1,SYT9,LRP1B,POC1B,ERICH3,RSPO2,MYO9A,PABPC1L2A,OPA1,OPCML,P2RY1,PDE3B,PIK3C2A,ZNF655,A2ML1,XRN1,TRHDE,SCHIP1,EPB41L4B,MINDY2,PPP2R5E,PPP3CB,RANBP3L,SNRK,WDR25,TMEM260,PTPRG,SH3TC2,ERI2,GTDC1,EXD2,C12orf49,RAVER2,ATP8B4,RTKN,S100B,PRCD,FNIP1,CASC3,GALNT10,KIF27,HSPA4L,CTXN2,SLC12A2,SLC14A1,ELMO2,MYH15,MBD5,PALLD,UNC80,RBM34,TRERF1,HECW1,RBM26,DIP2A,KANK1,TAC1,CAMTA1,SMG6,KLHL4,ANO4,ACSL6,ZEB1,PUM2,MTMR14,ERCC6L2,LRRC8A,TMPO,SYNPO2,TRPC3,TMEFF2,HIRA,BEST1,VSNL1,XRCC4,ANKS1B,SMARCAD1,CA10,STOX2,FAM13C,HNRNPA3,ZNF248,GAN" MicroRNA hsa-miR-760:mirSVR_highEffct hsa-miR-760:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.50E-62 1.41E-58 9.38E-62 8.64E-61 163 691 "NBAT1,ARID1A,BRAP,DOC2A,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APBB1,SHTN1,MIER1,SPTBN4,ARNTL,CAPRIN2,NUMB,ATP2B1,CADM3,CDK5R1,SYNJ2,CACNA1I,TRIM41,CAST,CBR1,TMEM257,AP4M1,CDC42,CDH8,CLTA,TJP2,AKAP7,ARMC8,PNKD,AKAP12,HINFP,GDA,SEC24C,VCAN,NCAN,PUM1,DCAF4,KATNAL2,KIAA0513,DGKB,DGKG,GIT2,ARMCX4,MYEF2,AK5,WDR20,DLG3,HS3ST2,DNAH9,FAM135B,SGK2,HIPK3,GPR61,ABI2,GOLGA7,TMEM35A,RAB9B,SRRM1,CACNG3,FCGR3A,FGF11,RGPD5,AKAP3,SORBS1,PDLIM5,GABBR1,GALC,DISC1,GDF9,RND1,LOXL3,GNG3,NUDT21,GRIA4,GRIN1,BTN2A1,KAT7,MFSD2A,LINC01102,HMGCR,SHISA6,KCNJ10,KHK,KIF2A,KIF5A,LOC100128239,MBNL1,MEIS2,MMP16,MOBP,ERICH3,GIT1,MSR1,PABPC1L2A,FXYD6,NF1,SLC11A2,NUMA1,GPR88,PBX1,PCMT1,GNG2,CAMKV,TMIE,PIK3CD,PLIN1,TRHDE,MDGA2,SPDL1,MARCH1,SLC25A48,RBBP6,SLC6A15,GTDC1,RGS3,RGS12,ARHGEF10L,NUDT11,EPHA10,SPIN3,ATP8B4,KCNIP3,ATXN7,SGK1,ITSN1,SHMT2,BCAN,ZNF365,SLC6A1,ATF7IP,ZNF667,SMARCD3,RCOR3,TTC17,SNRPN,NMNAT2,HECW1,ZC3H13,TAB2,EPB41L3,SS18,SEPT8,ABCC8,PJA1,TCF7,SYNE1,CYB561A3,AP4E1,SLC44A1,C5orf64,CDK20,WBP2,SLC13A3,NDRG4,UPF3A,PRDM2,SEMA3B,CAB39L,FAM13C,PHTF2,SLC4A10" MicroRNA hsa-miR-1284:PITA hsa-miR-1284:PITA_TOP PITA 3.94E-62 2.21E-58 1.48E-61 1.36E-60 128 427 "ABAT,KCNH8,FMNL2,AXIN2,PTCHD1,ADRB2,HACE1,OSBPL8,ADGRF5,ANK1,SEMA7A,ATP2B1,ATP2B2,B3GALT2,CARMIL3,JAZF1,LDLRAD4,CACNB2,KALRN,FOXN3,RAB33A,CLCN3,NRXN1,QKI,NIPBL,FEZ1,PLCXD3,PUM1,FRMPD4,SPOCK3,DLG2,CPEB2,RBM12,EML1,PAN3,EPB41L2,RCAN2,GPHN,EPS8,DENND4A,TAOK3,KAT8,FOXO3,SORBS1,ST6GALNAC3,GFRA1,PCDH17,GHR,SPIN1,GLRB,FAM19A2,SOX21,KLF12,MIER3,HMGB1,IGF1,JAK2,KCNMA1,KCNQ3,STMN1,ARHGAP12,PACRG,MAP2,MARK1,LDLRAD3,MEF2C,MITF,AFF1,NASP,NCAM1,ZC3H12B,NRCAM,NTRK3,PDE4B,EPB41L4B,PPP3CB,SNRK,PTCH1,TMEM260,FAM184A,ENOX1,OXR1,SLC6A15,REV3L,ROBO2,ATXN1,FAM19A1,FNIP1,TRA2B,SCAF8,KIF21A,ITSN1,FNDC3A,SLITRK3,SLC1A2,CXXC4,TMCC1,FAM126B,DOP1A,SOX2,CDK19,NFASC,TAB2,SMOC1,ERBIN,VAMP1,CAMTA1,WWC1,ANO4,TCF4,TRIM2,PSD3,ARHGEF12,ZFPM2,AKTIP,RBFOX2,ZNF384,EIF4ENIF1,PLEKHH2,VLDLR,ZIC2,SMARCAD1,CSDE1,RTN4,FRMD6,CBLN2,SOCS4,SENP7" MicroRNA hsa-miR-517*:mirSVR_highEffct hsa-miR-517*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.06E-62 3.40E-58 2.27E-61 2.09E-60 173 779 "KCNH8,NDRG2,KLHL32,CDC7,ADRB2,OSBPL8,CNTNAP1,MAGEE2,PPP4R4,CFLAR,MTMR2,GYG2,ZNF555,DIRAS1,HIP1R,MAP7,RUNX1T1,LDB2,CD86,CBFA2T2,LGI1,TAOK2,PLAA,CLCN3,MAGED1,ANKRD44,GDA,CRYM,FEZ2,ARHGEF10,VCAN,PDE4DIP,CFAP61,HDAC9,KATNAL2,YTHDC1,DDX46,RHOBTB1,SACS,GRIN3A,NYAP1,DNAJB6,ABCC5,EDNRB,FCF1,FSD1L,YAF2,VPS13B,EPHA5,MRPL37,CDKL3,DNAJC27,EXTL2,CLVS1,ACSL4,FCGR1A,FGF11,FGF12,FGFR3,IP6K2,EVL,NOP56,C2orf88,WDR83,UFM1,PDLIM5,CELF1,NSG1,SARAF,JPH4,RAPGEF6,NEU3,MSTN,BRD8,CBX1,GNAL,LILRA2,ATP2B1-AS1,GRID1,ATE1,AGBL5,NEGR1,DOCK7,SCIN,BRINP3,KCND2,KIF5C,LAMP2,STMN1,PACRG,MAT2A,MDM4,MMP16,MOBP,CD200,ZNF680,STK32C,CTNNA3,MTTP,P2RX7,PDCD2,PDE3B,PIRT,A2ML1,XRN1,ST8SIA5,HMGCLL1,TNPO2,PPARA,PRKACB,MAPK9,MASP1,APTX,C1orf109,PID1,ERI2,PBRM1,SETD5,CARF,PNMA8A,GSTCD,CCDC102B,LRRK2,ABCA11P,ATAT1,RTN1,ZNF331,SLC30A10,ITSN1,WDR47,FAM214B,LRRC55,SLC22A4,RCOR3,ANKRD36,SNAP25,SOX3,KDM4C,ZNF423,NPAS3,SS18,ELOVL4,KANK1,PLCB1,CYB561A3,FAM200B,GPR161,TMEM9,TLL2,RIMBP2,TPM4,ZMYND8,DCBLD1,PRR18,CLHC1,PLPPR2,NPDC1,CFAP298,ZIC3,ZNF711,TRIM9,GPR158-AS1,REEP1,EMSY,XKR7,PCDH15,WNK3,PLSCR4,PARP11,FAM13C,DOCK8,SSPN,RNF146" MicroRNA hsa-miR-520c-5p:mirSVR_highEffct hsa-miR-520c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-62 3.43E-58 2.28E-61 2.10E-60 171 762 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,EFS,ADGRV1,EYA1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,GFAP,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,STK32C,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,HMGCLL1,ING3,SPATA6,PPM1B,PRKACB,DIRAS2,DCHS2,PLPPR1,TMEM260,OCIAD1,ARID4A,GAL3ST4,GTDC1,RFX4,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-518f*:mirSVR_highEffct hsa-miR-518f*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-62 3.43E-58 2.28E-61 2.10E-60 171 762 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,EFS,ADGRV1,EYA1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,GFAP,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,STK32C,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,HMGCLL1,ING3,SPATA6,PPM1B,PRKACB,DIRAS2,DCHS2,PLPPR1,TMEM260,OCIAD1,ARID4A,GAL3ST4,GTDC1,RFX4,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-518d-5p:mirSVR_highEffct hsa-miR-518d-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-62 3.43E-58 2.28E-61 2.10E-60 171 762 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,EFS,ADGRV1,EYA1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,GFAP,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,STK32C,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,HMGCLL1,ING3,SPATA6,PPM1B,PRKACB,DIRAS2,DCHS2,PLPPR1,TMEM260,OCIAD1,ARID4A,GAL3ST4,GTDC1,RFX4,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-526a:mirSVR_highEffct hsa-miR-526a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.10E-62 3.43E-58 2.28E-61 2.10E-60 171 762 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,SEPT7,CCPG1,RAB28,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,YAF2,PHF20L1,EPB41,DENND4A,EFS,ADGRV1,EYA1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,GFAP,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,STK32C,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,HMGCLL1,ING3,SPATA6,PPM1B,PRKACB,DIRAS2,DCHS2,PLPPR1,TMEM260,OCIAD1,ARID4A,GAL3ST4,GTDC1,RFX4,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZIC1,ZNF45,POLR3H,PCBP1-AS1,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-103:PITA hsa-miR-103:PITA_TOP PITA 7.74E-62 4.35E-58 2.88E-61 2.66E-60 123 395 "ASIC1,SLITRK1,GALNT13,AXIN2,SEMA6A,OGT,ANK1,CNTNAP1,ARHGAP5,MARCH3,ZBTB10,DCAF5,NRP2,CDK5R1,CACNA2D1,THSD7A,RUNX1T1,DCLK1,CHRM1,CLCN3,CLOCK,ERC2,PPP6R2,USP6NL,LONRF1,YTHDC1,JAKMIP2,DLG4,SLC12A6,ST8SIA3,TSPAN5,SEMA3D,PHF20L1,EIF5,PLEKHA1,CORO2B,OLFM1,PHYHIPL,GABRB1,GABRG2,PCDH17,SPIN1,FERMT2,TMEM121B,ZHX1,BACH2,HLF,AGFG1,C5orf24,SLC35G1,KIF5A,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,NEXMIF,ZC3H12B,NF1,NFIA,NOVA1,PDE3B,CDK14,CAMKV,PIK3R1,PLP1,FAT3,POU3F2,MINDY2,LRRN3,PPP2R5C,CNNM2,SNRK,TMEM260,PID1,BSDC1,PRRT2,FBXW7,SYNDIG1,CLIP1,SALL1,ATXN1,SCN2A,SCN3A,SCN8A,PUF60,KIF21A,ITSN1,SH3GL2,PPM1E,CPEB3,NLGN1,SLC1A2,FAM81A,SLC8A2,SLC20A2,SMARCE1,ZHX3,TAB2,LRRC4,VAMP1,PLCB1,SYN2,ADGRL3,SATB2,RPGRIP1L,WASHC4,FRYL,AHCYL2,DICER1,ZFPM2,TGFBR3,TPD52,TPM1,PRMT8,TRPC1,AMOT,BCL2L13,NSD2,ZIC1,ZNF711,GOPC,ADAMTSL3" MicroRNA hsa-miR-107:PITA hsa-miR-107:PITA_TOP PITA 7.74E-62 4.35E-58 2.88E-61 2.66E-60 123 395 "ASIC1,SLITRK1,GALNT13,AXIN2,SEMA6A,OGT,ANK1,CNTNAP1,ARHGAP5,MARCH3,ZBTB10,DCAF5,NRP2,CDK5R1,CACNA2D1,THSD7A,RUNX1T1,DCLK1,CHRM1,CLCN3,CLOCK,ERC2,PPP6R2,USP6NL,LONRF1,YTHDC1,JAKMIP2,DLG4,SLC12A6,ST8SIA3,TSPAN5,SEMA3D,PHF20L1,EIF5,PLEKHA1,CORO2B,OLFM1,PHYHIPL,GABRB1,GABRG2,PCDH17,SPIN1,FERMT2,TMEM121B,ZHX1,BACH2,HLF,AGFG1,C5orf24,SLC35G1,KIF5A,AQP11,MBNL1,CHIC1,LRP1B,SCAMP5,NEXMIF,ZC3H12B,NF1,NFIA,NOVA1,PDE3B,CDK14,CAMKV,PIK3R1,PLP1,FAT3,POU3F2,MINDY2,LRRN3,PPP2R5C,CNNM2,SNRK,TMEM260,PID1,BSDC1,PRRT2,FBXW7,SYNDIG1,CLIP1,SALL1,ATXN1,SCN2A,SCN3A,SCN8A,PUF60,KIF21A,ITSN1,SH3GL2,PPM1E,CPEB3,NLGN1,SLC1A2,FAM81A,SLC8A2,SLC20A2,SMARCE1,ZHX3,TAB2,LRRC4,VAMP1,PLCB1,SYN2,ADGRL3,SATB2,RPGRIP1L,WASHC4,FRYL,AHCYL2,DICER1,ZFPM2,TGFBR3,TPD52,TPM1,PRMT8,TRPC1,AMOT,BCL2L13,NSD2,ZIC1,ZNF711,GOPC,ADAMTSL3" MicroRNA hsa-miR-136*:mirSVR_lowEffct hsa-miR-136*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.72E-62 4.90E-58 3.25E-61 2.99E-60 175 798 "NCKAP5,PSMG3-AS1,KIDINS220,DPY19L2P4,INTS2,LRRC7,ANK2,PKP4,BCAS1,AQP6,CDC14B,PPP4R4,MARCH3,ASPH,ATP2B2,BMPR1B,DST,ARHGEF7,BTK,CACNA1A,VXN,VSTM2A,RUNX1T1,LARGE1,MAGI1,ZBED5,PPT2,CNTN1,ARMC8,COL4A5,SLC4A7,RCHY1,IFFO1,CREM,RNF14,VCAN,PHACTR3,SLITRK5,CTH,CTNND2,CCDC144A,DOCK4,GAPVD1,DGKB,C8orf34,TIAM2,C2CD2L,SNAP91,NTM,KBTBD11,DLX1,EXOG,DMD,USP3,DPYSL2,DTNA,FAM78B,DNM1L,GOLT1B,HIPK3,KLHL5,PHF20L1,ABI2,EGR3,EMX2,EPB41L1,LRRC17,SRARP,ANKMY1,ADGRV1,ABCA8,ST3GAL6,KIAA1109,IP6K2,EFCAB2,FAM49B,NPTN,CELF1,ABLIM2,ZMAT1,STAG2,GABRB3,GAP43,DISC1,IGSF5,COPS8,TNRC6A,MAP4K5,HMGB1,C2orf72,NKD1,LRRCC1,KCNC1,KIT,KLRC3,STMN1,SMAD1,MAN2A2,AQP11,MBP,AFDN,MYCN,NDUFA5,NF1,SLCO1C1,NFE2L2,PCDH9,PDE4B,PDGFRA,SSH1,SEMA5B,XRN1,RC3H2,SH3KBP1,PPM1B,PRKCZ,MAPK9,WBP1L,STK32A,C1orf109,KHDRBS2,SLC6A15,RFX3,TTLL7,RIT2,CCDC82,ABCA11P,CLIP1,RXRG,MRAS,SH3GL2,FNDC3A,PPP4R3A,SLN,SORCS3,SOX3,TAB2,THSD1,STAU1,ZSCAN29,DNAJC9,KAZN,TAF9,ADGRL3,IQCE,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,AP4E1,TIAM1,SYNPO2,AMACR,TRPC3,TRPS1,TMEFF2,VLDLR,XRCC4,ZIC2,LYPD6,CADM2,NAV3,WNK3,FAM13C,MARCH8,HNRNPA3,PHTF2,CASC15,CBLN2,SENP7" MicroRNA hsa-miR-1226*:mirSVR_highEffct hsa-miR-1226*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-61 6.55E-58 4.34E-61 4.00E-60 166 723 "CLK4,ADD3,SORCS1,ADORA3,DPY19L2P4,ADGRF5,ALAD,AMPH,OGT,SUGT1P4-STRA6LP-CCDC180,SHROOM2,PPP4R4,CAPRIN2,DACT3,BRINP2,CCAR2,EIF4G3,CARMIL3,KSR1,BTK,RAB29,DDR1,CACNA2D1,NFS1,CCKBR,LRBA,CDO1,SYNPR,QKI,FHL5,SMARCAL1,CP,SEC31B,GDA,CLIP3,CS,SNCAIP,FEZ1,SLITRK5,ZNF337,ARMCX4,C8orf34,ZEB2,HEPH,BLOC1S6,DLG4,GRIN3A,DNM1,ACOT8,DTNA,ABCC5,ANKRD46,CNNM1,SORBS3,CERCAM,C8orf37,EMX2,SEZ6,RTN3,CEP78,ZSCAN30,TESK2,C2orf88,FAM49B,CGREF1,PNMA2,AP4B1,NRG3,FYN,GABRG2,GAD2,ZNF274,NEU3,TUBA8,SULT1C4,GLS,ADGRA3,TDRKH,PCLO,GRIA2,GRIA4,GRM1,KAT7,BVES,C1orf94,ARHGAP36,VSIG4,MSL1,FAM95B1,JAK1,SLC35G1,KCNB1,KCNH2,KCNK1,KCNMA1,KIF5A,VWA5A,ARHGAP12,MAOB,MTTP,NCAM2,NDP,NUMA1,ODF2,PDYN,DUSP26,SEMA5B,EXOSC10,SCHIP1,SIDT1,GDPD2,UHRF1BP1,ZSCAN32,PTPRB,OCIAD1,MARCH1,OXR1,RIT2,ZNF532,ABCA11P,ATAT1,TRAPPC13,FAM192A,TNFRSF19,TRIM46,ITSN1,SH3GL2,ZNF365,FAM81A,FAM214B,LRRC55,SMARCC2,SORCS3,SMARCE1,RCOR3,RIMS1,MYO16,KIF21B,KDM4C,NPAS3,TAB2,COLGALT2,ADHFE1,ADAMTS17,UNC5D,TRIM2,ICAM5,TPM1,TPM2,ELP5,PDSS1,AMACR,FNDC5,RPL7L1,UBE3A,WNT7A,PCDH20,ZIC3,PLPP4,ZXDA,MFF,DNALI1,PARP6,RGS7BP,UBE3B,ADAMTS10" MicroRNA hsa-miR-520f:PITA hsa-miR-520f:PITA_TOP PITA 1.29E-61 7.24E-58 4.80E-61 4.42E-60 131 452 "ABR,SLITRK1,MTUS1,HECW2,OSBPL8,AK2,ANK1,APP,TMEM263,STX16,ATP2B2,DPY19L3,ARHGEF7,MTMR3,JAZF1,CALB1,PRC1,CDC25B,CDH2,LGI1,CFL2,LETMD1,AKAP5,ACBD5,IGDCC3,ZNF385A,CREB5,SOCS5,RUBCN,USP6NL,TOX,RASSF2,SIRPA,ZNF804A,ZC3H11A,HS3ST4,ABCC5,MBNL2,KMT5B,PAN3,EMX2,DNAJC27,EZH1,CACNG3,EFEMP1,ATP8A1,MED12L,CAMSAP1,FOXO3,AFF2,MAP7D2,FAM222A,ZHX1,BACH2,IL6ST,OLFM3,SYTL4,MARK1,MBNL1,MEF2C,NOVA1,NPTX1,NRCAM,OMG,OPCML,GPR137C,PCDH9,CDK14,LRP12,FAT3,PKIA,PKN2,TMEM260,PTPRD,ARID4A,RDX,RET,FIGN,SLC25A36,ALG9,LGR4,AMER2,ATXN1,SCN2A,LRRTM4,ITSN1,MAGI3,FNDC3A,SLITRK3,WDR37,FAM214B,TET1,RCOR3,SOX5,HECW1,ARHGAP26,CDK19,LMO3,RGL1,STXBP1,KLHL7,ARHGEF9,PLCB1,SYT1,ANKRD12,CAMSAP2,FBXW11,CUX2,ZFPM2,DDHD1,TNS1,RBFOX2,NR2C2,TRPS1,TOM1L2,VLDLR,ZNF711,LYPD6,TMEM237,SYNC,UPF3A,RGMA,PRDM8,PRDM10,NAV3,WIPF2,FAM13C,PAK5,ADAMTSL3,VANGL2,MSRB3" MicroRNA hsa-miR-1264:PITA hsa-miR-1264:PITA_TOP PITA 1.73E-61 9.69E-58 6.41E-61 5.91E-60 131 453 "ARID1A,USP31,GPR158,LRRC7,SEMA6A,SRPX,OGT,APBA2,APP,AQP4,TMEFF1,CDK13,STK33,ADGRB3,JAZF1,THSD7A,ZMYM4,ADGRG1,SRSF11,FOXN3,CNOT8,SLIT2,NRXN3,NRXN1,QKI,ARHGEF6,CNR1,AHCTF1,CS,ATRNL1,CHD5,SOCS5,APPL1,ST18,TOX,SCRN1,ARMCX2,G3BP2,RABGAP1L,DYNC1I1,RBM12,GPR61,EGR3,TMEM132E,EIF5,STARD3NL,PAN3,CLVS1,TESK2,FGF13,SUCO,ANKFY1,AFF2,FAM49B,GABRB3,SPIN1,GLS,GNAO1,GRIA2,FAM19A2,AGFG1,SMAP1,LRRCC1,PLD5,ITGAV,JAK1,SLC35G1,KCNA1,KCNN2,ARHGAP12,NCOA7,AQP11,CHIC1,LRP1B,MEIS2,MYO5A,MYO7A,NEXMIF,PABPC1L2A,NDP,OPCML,PRTG,GPR85,XRN1,PPP3CB,PTK2,TMEM260,PTPRO,FAM120C,PTPRZ1,MSANTD2,REV3L,PRRT2,TTLL7,ZFHX4,SETD5,RORB,FBXW7,KCNIP1,ATXN2,ELMOD1,TRA2B,CPEB3,MAGI3,FBXO11,NLGN1,SLC1A3,PPP4R3A,CPEB4,RIMS1,MYT1L,SOX11,NFASC,ITPRID2,SYNE2,CAMSAP2,FBXW11,SATB2,TCF12,DOCK9,PSD3,ARHGEF12,ZFPM2,SGK3,ZBTB14,KCNT2,PLPP4,ZFAND5,SLC38A1,RNF103,SOCS4" MicroRNA hsa-miR-1252:PITA hsa-miR-1252:PITA_TOP PITA 1.85E-61 1.04E-57 6.87E-61 6.33E-60 119 371 "XKR4,PWWP2A,HECW2,OSBPL8,SEMA6A,SPOP,MAGEE2,PPFIA3,AQP4,CADPS,NCOA1,BCL7A,CDK5R1,FUBP1,BSN,FOXN3,NRXN3,NRXN2,CLTA,CNTN1,AKAP6,MAGED1,CRY2,SLITRK5,HDAC4,PHYHIP,ZC3H11A,POM121,CALN1,DPYSL2,ABI1,DUSP9,EFNA3,EIF4G2,PAN3,RCAN2,WAC,CACNG3,FGF12,NBEA,TMEM151A,STAG2,GABRB3,IP6K3,C15orf41,ARFIP1,PCDH17,GHR,TTBK1,GLRB,GRM1,RNF165,MAP4K5,MAEL,KCNMA1,KIF5C,SMAD1,MAP2,MAT2A,MBNL1,MITF,MYCN,NBL1,PDE4B,PLP1,CDIP1,STRN3,MINDY2,PPP1R1A,CNTLN,TTLL7,RIC8B,PBRM1,SETD5,SCN2A,FAM19A1,SOX6,SGK1,KIF21A,CPEB3,CHD9,FBXO11,RIMS1,SON,MYT1L,SOX5,DOK5,ZNF423,SPTB,CDK19,POGZ,SYT11,CAMTA1,MCF2L,ADGRL3,TBL1X,TCF4,TCF7,RPGRIP1L,TCF12,AZIN2,DICER1,SIRT1,FNDC5,TUB,CADM1,FAM155A,NSD2,PORCN,XPO1,ZIC1,ZIC2,REEP1,POLR3H,SMARCAD1,CA10,RGS7BP,PHTF2,SOCS4" MicroRNA hsa-miR-380:PITA hsa-miR-380:PITA_TOP PITA 2.03E-61 1.14E-57 7.52E-61 6.93E-60 123 398 "PWWP2A,SNX30,PCDH19,OSBPL8,LRRC7,OGT,LRCH2,APP,TMEM263,ARHGAP5,ZBTB10,SLC4A4,B3GALT2,DPY19L3,MTMR2,CACNB4,KALRN,KRIT1,CDH10,NRXN1,ACBD5,CREB5,FRMPD4,ZFYVE16,CTIF,TIAM2,HP1BP3,DLG2,DMD,ABI1,GOLT1B,KLHL5,EIF4G2,EPB41L1,CLVS1,SMC2,CAMKK2,OGA,STAG2,C15orf41,PCDH17,GK,GLRB,GPD2,STON1,IL1RAPL1,ATXN2L,BACH2,HMGCR,AGFG1,C5orf24,LIX1,BRINP3,LRRTM3,ITGAV,KCNA4,KIF2A,MAP2,AQP11,MBNL1,MEF2C,KITLG,MYO5A,NAP1L1,OPCML,KCNK10,GLIPR1L2,CNTN3,PCDH8,SH3KBP1,SNRK,PTPRE,TMEM255A,RADX,RDX,SLC6A15,FIGN,UBR7,DCUN1D2,ALG9,SMPD3,ELMOD1,SOX6,NLGN4Y,SHC4,CHD9,FNDC3A,WDR37,CCDC88A,CPEB4,SNAP25,FAM126B,SOX11,SP4,ENKUR,ZNF423,CDK19,RBM26,CLASP2,LARP4,STAU1,ADAMTS17,PLCB1,SYT4,AGTPBP1,PUM2,ZFPM2,NR2C2,TRPS1,CADM1,UBE3A,SLAIN1,FLRT2,VSNL1,XRCC4,SMARCAD1,RGS7BP,FAM13C,HNRNPA3,PHTF2,SSPN,FXR1,SENP7" MicroRNA hsa-miR-133b:mirSVR_highEffct hsa-miR-133b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.31E-61 1.30E-57 8.56E-61 7.89E-60 154 628 "CSMD2,SNX30,SLC24A4,CC2D2A,LRRC7,PITPNM2,LCORL,CDK13,PDE8B,TTLL9,SEC11C,BMP7,KALRN,PTBP2,VXN,CAST,NFS1,CLDN10,CD86,LRBA,CLTA,SLC4A8,TBPL1,ZFP28,CNRIP1,HAPLN1,ANKRD44,CSNK1G3,NCAN,CMTM5,CTH,BOC,PHF19,MAML1,IST1,DCC,ZEB2,ZC3H11A,SV2A,DLG2,DMTF1,DPP6,ANKRD46,EGFR,TENM1,PAN3,COQ7,EPHA5,KCNMB2,CEP85L,EFEMP1,MED12L,CAP2,SMC2,SPECC1,GALNT15,ARPP21,GALR1,ALDH1L1,SRCAP,POLL,GPD2,GPM6A,TDRKH,GRIA4,RFFL,GRM5,ATOH8,HMGB1,CFAP126,RBPJ,KCNMA1,LAMP2,VWA5A,ARHGAP12,NCOA7,MEIS1,MEIS2,MEST,CD200,NME4,NPTX2,DPY19L2P2,PDE1C,HMGCLL1,TRHDE,ING3,SEPT4,PRKCB,SAMD9,LRRC49,SIDT1,SNRK,CNTLN,PTH1R,TMEM260,PTPRD,PTPRH,PTPRO,PTPRZ1,RALGDS,DBX2,PRRT2,ERI2,RGS3,EXD2,CARF,ZC3H14,KCNIP1,CSRNP3,SGK1,SH3GL2,FRMPD1,FHOD3,ST3GAL3,CTXN2,BTBD3,SLC6A1,ZFP1,RIMS1,SNCA,SNRPN,SRPK2,ZSCAN29,SYT1,ANKRD28,TACC1,ANKRD12,TBCEL,FBXW11,TCF7,ARHGAP9,CHST8,C18orf54,AP4E1,NPL,TPM3,TPM4,ELP5,AMACR,DCBLD1,TUBB1,PITPNB,BEST1,ZIC3,ELFN1,CELF4,SCG2,PCDH15,PLSCR4,C12orf4,DOCK8,KAT6A,HNRNPA3" MicroRNA hsa-miR-133a:mirSVR_highEffct hsa-miR-133a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.31E-61 1.30E-57 8.56E-61 7.89E-60 154 628 "CSMD2,SNX30,SLC24A4,CC2D2A,LRRC7,PITPNM2,LCORL,CDK13,PDE8B,TTLL9,SEC11C,BMP7,KALRN,PTBP2,VXN,CAST,NFS1,CLDN10,CD86,LRBA,CLTA,SLC4A8,TBPL1,ZFP28,CNRIP1,HAPLN1,ANKRD44,CSNK1G3,NCAN,CMTM5,CTH,BOC,PHF19,MAML1,IST1,DCC,ZEB2,ZC3H11A,SV2A,DLG2,DMTF1,DPP6,ANKRD46,EGFR,TENM1,PAN3,COQ7,EPHA5,KCNMB2,CEP85L,EFEMP1,MED12L,CAP2,SMC2,SPECC1,GALNT15,ARPP21,GALR1,ALDH1L1,SRCAP,POLL,GPD2,GPM6A,TDRKH,GRIA4,RFFL,GRM5,ATOH8,HMGB1,CFAP126,RBPJ,KCNMA1,LAMP2,VWA5A,ARHGAP12,NCOA7,MEIS1,MEIS2,MEST,CD200,NME4,NPTX2,DPY19L2P2,PDE1C,HMGCLL1,TRHDE,ING3,SEPT4,PRKCB,SAMD9,LRRC49,SIDT1,SNRK,CNTLN,PTH1R,TMEM260,PTPRD,PTPRH,PTPRO,PTPRZ1,RALGDS,DBX2,PRRT2,ERI2,RGS3,EXD2,CARF,ZC3H14,KCNIP1,CSRNP3,SGK1,SH3GL2,FRMPD1,FHOD3,ST3GAL3,CTXN2,BTBD3,SLC6A1,ZFP1,RIMS1,SNCA,SNRPN,SRPK2,ZSCAN29,SYT1,ANKRD28,TACC1,ANKRD12,TBCEL,FBXW11,TCF7,ARHGAP9,CHST8,C18orf54,AP4E1,NPL,TPM3,TPM4,ELP5,AMACR,DCBLD1,TUBB1,PITPNB,BEST1,ZIC3,ELFN1,CELF4,SCG2,PCDH15,PLSCR4,C12orf4,DOCK8,KAT6A,HNRNPA3" MicroRNA hsa-miR-519c-5p:mirSVR_highEffct hsa-miR-519c-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-518e*:mirSVR_highEffct hsa-miR-518e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-522*:mirSVR_highEffct hsa-miR-522*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-519a*:mirSVR_highEffct hsa-miR-519a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-519b-5p:mirSVR_highEffct hsa-miR-519b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-523*:mirSVR_highEffct hsa-miR-523*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-61 1.40E-57 9.18E-61 8.46E-60 167 735 "RALGAPA1,KCNH8,CLK4,KLHL32,SORCS1,OSBPL1A,SMIM17,SEMA6A,ANK2,ANK3,MAP4K3,CNTNAP1,APAF1,BCAS1,NCOA1,NUMB,DPY19L3,ADGRB3,MPDZ,BAIAP3,CALM1,INA,CD86,CCPG1,NRXN3,CLCN3,NRXN1,NRXN2,FBXO7,CNR1,AKAP6,COL4A5,AKAP5,ZFP28,AKAP12,ANKRD44,SNCAIP,PHF14,KATNAL2,DGKB,ELMO1,HP1BP3,RHOBTB1,KBTBD11,ATN1,ECM2,WDPCP,EDN1,HIPK3,PHF20L1,EPB41,EFS,ADGRV1,AMZ2,ACSL4,IP6K2,SPECC1,ATP6V1H,CELF1,DLL3,STAU2,MSANTD4,SARAF,TBR1,NRG3,ZNF512,HRASLS5,GABRB1,BRPF3,JPH4,DISC1,ZNF638,GPD2,NR3C1,DHX35,HSP90AA1,ZNF546,IGFBP1,KNDC1,BRINP3,NME9,OLFM3,KCNJ11,CREG2,MAP2,MOBP,MRPL42,MSR1,SCG3,MTTP,MYO9A,NELL2,NF1,NRCAM,SMIM11A,ODF2,LOC100128398,PDE3B,PIRT,FAM218A,PLCB2,ING3,PPM1B,PRKACB,DIRAS2,DCHS2,CNTLN,PLPPR1,TMEM260,OCIAD1,ARID4A,GTDC1,RFX4,TTLL7,SEC61A2,DCUN1D2,ROBO2,ARMH4,RPS20,KCNIP2,NCBP3,MAPK12,SCN3A,TNFRSF19,ARX,PPP4R3A,FAM214B,SLC6A1,KBTBD4,SLC14A1,SNCA,IDI2-AS1,DBNDD2,NPAS3,SPART,LMO3,ITPRID2,SS18,KLHL7,FGD4,SYT1,DDHD2,DNMBP,SIN3B,DMXL2,RPGRIP1L,PUM2,FRYL,DDHD1,FAM124A,TP53BP2,TPD52L2,NPL,TPM3,ZNF384,METTL3,TSC1,SLC13A3,ZNF45,POLR3H,PCBP1-AS1,PRDM2,GDPD5,SLC17A7,TIGD6,RNF170,SLC4A10" MicroRNA hsa-miR-768-3p:PITA hsa-miR-768-3p:PITA_TOP PITA 2.69E-61 1.51E-57 9.91E-61 9.13E-60 117 359 "ERMN,NLGN4X,KIAA1324,SPOP,LCORL,ARNTL,SLC4A4,RNF182,FUBP1,JAZF1,PTBP2,USP6,ZMYM4,FOXN3,HOMER3,BAG4,RIMS4,APPL1,PLCXD3,RIMS2,ARHGAP24,TOX,LONRF1,YTHDC1,SNAP91,GRIN3A,CDON,DNAJB6,KLHL5,EIF4G2,AFF2,FUT9,BRPF3,GATM,MSTN,SESN1,PCDH17,SPIN1,GLRB,GLS,GPM6A,TMEM121B,PCLO,GRIA4,PSIP1,ADAMTS6,BACH2,NEGR1,AGFG1,C5orf24,ZIC5,LRRTM3,OLFM3,STXBP5,MID1,RSPO2,MYCN,NEXMIF,PCDH8,PCDH9,PDE4B,SERPINI1,POU3F2,PPP3CB,RELN,SNRK,UHRF1BP1,OXR1,ARID4A,REV3L,ZFHX4,SETD5,ROBO2,NCBP3,SEMA6D,ATXN1,SCN8A,CASC3,PPM1E,CPEB3,NTNG1,AMBRA1,NLGN1,SEPHS1,SLC12A2,SLC12A4,TET1,SNAP25,FAM126B,SOX1,SOX5,MYCBP2,CLASP2,POGZ,LARP4,NKAIN2,STXBP1,ADGRL3,RPGRIP1L,DOCK9,PSD3,PUM2,ZFP91,RIMBP2,NR2C2,TSN,FAM155A,AMOT,XRCC4,ZIC3,CA10,SLC17A6,RGS7BP,RTN4,NETO2,DPF3,RNF146" MicroRNA hsa-miR-323b-3p:mirSVR_highEffct hsa-miR-323b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-61 1.86E-57 1.22E-60 1.13E-59 149 590 "CLK4,SORCS1,KLHL13,TXNDC16,LRCH2,DST,SYNJ1,FUBP1,C1QC,GPC2,IL33,USP6,CHN1,CHN2,KMT2C,QKI,COL9A1,BTF3L4,SLC4A8,ABI3BP,AHCTF1,RTTN,ZFP28,CHD1L,NECTIN3,GDA,CSF1,OSBPL3,VCAN,DOCK4,ZFYVE16,BRINP1,HEPH,SV2B,SPOCK3,CHRDL1,GRIN3A,DMD,CPEB2,ECM2,ABCC9,E2F5,SNX29,EIF4G2,TENM1,FAM198B,SCML2,FER,FGFR3,SUCO,FOXM1,PSD2,NBEA,TMEM107,PDLIM5,CELF1,OGA,GABRG2,DISC1,NEU3,MSTN,RUNDC3A,COPS8,RAB40B,FERMT2,GPR22,GPR37,GRM7,KAT7,WIF1,MAEL,C5orf24,ZNF385B,NME9,ITGAV,METTL21A,KCNA2,CLVS2,KCNMA1,STXBP5,STMN1,MBNL1,KCTD6,MITF,MOBP,ZNF92,CNOT4,NOVA1,NPTX2,HCN1,GPR85,OLA1,NALCN,PKD1,FTO,PMP22,ING3,PPP3CA,PPP3CB,PPP3CC,DIRAS2,FAM120C,ACSM5,USP47,DBX2,ZYG11B,TRIM68,UBR7,MRPS18A,EXD2,ACER3,ABCA11P,SAFB,SCN2A,LINC00461,CPEB3,NTNG1,FBXO11,PAAF1,NAPB,ZFP1,SNCA,CABCOCO1,SNRPN,PDZD2,BDP1,ZC4H2,ERBIN,VPS13A,FAM208A,AGTPBP1,EHBP1,DOCK9,PUM2,USP32P1,SLC44A1,LRRC8A,TPD52,METTL3,NEIL2,ZMYND8,CADM1,CLEC2L,MTCH1,MEAF6,VSNL1,ZNF189,UPF3A,RNF103" MicroRNA hsa-let-7b-5p:Functional MTI Functional MTI miRTarbase 4.74E-61 2.66E-57 1.75E-60 1.61E-59 219 1215 "ABCF1,ASIC1,FZD9,KIDINS220,MTUS1,ZNF578,CEP126,ZNF687,AMPH,FAM131A,AQP6,IGDCC4,ASPA,ATP1A1,ATP2A2,ALDH7A1,ATP6V0A1,BACH1,BCL7A,BMP7,WASF1,FOXK1,CA12,MAP7,FMNL3,ENTPD6,CD81,L3MBTL4,TBRG4,ADGRG1,FADS2,QKI,NIPBL,PCYT1B,AHCTF1,SLC35F1,ENTPD4,CRY2,NCOR1,CS,LRIG1,IPCEF1,PPP1R16B,APPL1,PUM1,GAPVD1,INTS1,SCRN1,IP6K1,DNAL1,YTHDC1,ZC3H11A,POM121,SMG7,MTX3,SEC16A,DMD,DNAH9,RCAN1,E2F5,E2F6,EDN1,ANKRD46,RBM12,SH3GLB1,EIF4G2,PLEKHO1,MTSS1L,GPHN,MRPL37,TUBA1B,TUBB4A,SCML2,DLC1,TOMM40L,POLR1B,SEC23B,TRMO,PDLIM5,FAM49B,NPTN,ERGIC3,CELF1,AHCYL1,BRPF3,SALL3,DISC1,GATM,SRCAP,NFU1,PPARGC1A,TXNL4A,TOX3,POLL,GNAS,PRRC2B,GPM6B,FUT10,TUBA1C,RFFL,ATE1,RABL2A,GYG1,ATXN2L,HMGB1,HSF2,HSP90AA1,C5orf24,RBPJ,USP54,IL6R,IBA57,KIF2A,KPNA5,NAT8L,MAP4,MDM4,MEF2C,MOV10,DBNL,MSI1,THYN1,NACA,NAP1L1,NME4,SLC11A2,NRDC,NUCB2,OPRL1,PRTG,PDGFRA,XRN1,NLE1,FTO,ZNF426,SEPT4,PPP2R5E,WDR25,PIGG,QDPR,USP47,OXR1,RBBP6,MSANTD2,RDX,DPF2,FIGN,KLHL11,ZFHX4,SETD5,C12orf49,LGR4,WLS,FOXRED2,SAFB,DRAXIN,ATXN2,FOXRED1,SUPT20H,KIF27,SCAF8,CPEB3,FNDC3A,DZIP1,PAAF1,CPEB4,SMARCA4,SMARCC2,RBM34,SON,ERC1,PEG10,ARHGAP26,DBNDD2,MCF2L2,TAB2,TROVE2,EPB41L3,NXT2,SYNE2,FNDC9,SYT1,TAF9,DNMBP,KIAA0930,USP22,SYNE1,SLC19A3,PSD3,NSD1,AHCYL2,DICER1,TGFBR3,ZNF106,GZF1,TIAM1,TJP1,CBX5,TLR4,NR2E1,LRRC8A,RBFOX2,TPD52L2,TPM4,TST,TUBB2A,UGT8,TBC1D15,ZNF28,DPYSL5,SMARCAD1,DHX33,WNK1,SLC38A1,GDPD5,C12orf4,MRPL47,NUP214,NHSL1" MicroRNA hsa-miR-190a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.09E-61 3.98E-57 2.61E-60 2.41E-59 156 649 "ABCF1,ADD2,GRAMD1B,NLGN4X,ZNF608,HACE1,TAOK1,PCDH10,APP,MIER1,MARCH3,BACH1,FUBP1,CA12,THSD7A,RUNX1T1,CBR1,CD81,TBRG4,CFL2,B4GALT6,SLC24A2,C4orf33,QKI,SLC25A27,TBPL1,ACBD5,ANKRD44,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,DBT,PITPNC1,SPATA2,SV2B,G3BP2,CDON,CPEB2,YAF2,MBNL2,ABI2,PLEKHA1,CERCAM,TUBD1,RCAN2,EPHA5,ACSL4,FER,KIAA1109,TMEM164,TRMO,ZBED3,NPTN,MPP6,GABRG1,GCK,MMADHC,PPARGC1A,COPS8,KCNMB4,TPPP,GRID1,GRIK3,NR3C1,BVES,INSYN1,BACH2,USP51,NEGR1,HSF2,IGF1,IGFBP1,ZIC5,DOCK7,SCIN,IL6ST,KCNB1,CLVS2,KCNJ3,KLHL23,KCNK1,KCNN3,L1CAM,FGFBP3,SMAD9,MMP16,CCDC80,MYBPC1,NEXMIF,NCAM2,NELL2,NFIA,NTRK3,OPCML,PIK3R1,XRN1,PLP1,PURG,PRRX1,PPP1R1A,PPP2R5E,PROX1,SNRK,PTPRD,RAB5B,CEP97,SH3TC2,PRIMA1,RIC8B,CARF,FBXW7,ACER3,AP1AR,CSRNP3,FAM19A1,LRRC55,SLC6A8,SLC8A1,RAB3GAP1,SLC12A2,WDTC1,SOX5,ZHX3,ERC1,STAU1,AJAP1,PRRC2C,SYP,TMEM178B,TRIM2,AHCYL2,SIK3,ZMAT3,HHIP,CSMD1,NR2C2,CADM1,PITPNB,OSBP2,KCNK12,ZBTB16,SMARCAD1,SLC30A4,PMEPA1,MAP3K12,ZXDA,LRP8,EVI5,STOX2,ADAMTS9,FAM182B,KAT6A,SSPN" MicroRNA hsa-miR-3196:mirSVR_lowEffct hsa-miR-3196:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.90E-61 5.00E-57 3.28E-60 3.02E-59 150 602 "DPF1,FAM43B,RNF157,PWWP2A,BEGAIN,EP400,DGKZ,CDK10,MADD,SPTBN4,ARHGDIA,ARHGDIG,ATP1A3,CARMIL3,KSR1,KALRN,TRIM41,BRSK2,ARHGEF1,ENTPD2,NUMBL,JAM2,NRXN3,FADS2,CCDC151,FAM149A,NRG2,ZNF385A,ANKRD44,NCOR2,GDA,PLCH2,SLITRK5,SIRPA,DCTN1,RUSC2,SMG7,AK5,DLG4,DTNB,ANKRD46,EEF1A2,CACNG7,EFNA3,CELSR3,EIF1,OLIG2,MTSS1L,EPHB1,ANKRD13B,RTN3,EXTL1,REEP2,PTK2B,KAT8,BAIAP2,AGAP2,SEMA6C,ZNF274,ALDH1L1,TUBA8,ZNF276,ATF7,STMN2,GRB10,C1QL4,GRIN1,LINGO1,IGSF21,PACSIN2,ATXN2L,HPSE2,HMGCL,HPCA,IDH3A,LRRC25,KNDC1,IL11RA,KLRC3,L1CAM,LRRC4B,PPM1L,XRRA1,MSI1,RTL5,FXYD7,FXYD6,NEUROD2,SLCO1C1,DNHD1,NRGN,OGG1,PBX1,PDE4A,PFKFB3,NLGN3,CCSER2,PLEC,PILRA,POLR2F,VSTM2L,CNNM2,RAB3A,SUSD4,PRRT2,ARHGEF10L,SYNDIG1,ATAT1,YJEFN3,STX1B,FOXRED2,ITSN1,ARX,MYO18A,SLC6A9,SLC12A4,SNRPN,SOX10,TSPYL2,MCF2L2,C11orf87,NCDN,STX1A,SYN1,ARC,SYN2,EXOC7,PDLIM2,TBX15,TCF4,NEU4,NAT16,TNS2,TMEM121,FBXL16,TMEM9,TNNT1,PIK3R5,NPL,C9orf85,SMUG1,CLEC2L,ZIC2,FMN2,PRDM2,PRDM8,TMEM178A,TMEM163,GJC2,JPH3" MicroRNA hsa-miR-20b-5p:Functional MTI Functional MTI miRTarbase 9.82E-61 5.52E-57 3.61E-60 3.33E-59 187 917 "ADAR,FMNL2,ADD1,FZD9,SORCS2,ZNF578,KIF6,SEMA7A,USP28,GPAM,CAPRIN2,ATP1B3,ATP2B1,MTMR9,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,FOXK1,MAP7,FMNL3,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,SLC4A7,ACBD5,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,FEZ2,SOCS5,UBXN2A,DCAF8,KIAA0513,DNAL1,YTHDC1,ELMSAN1,PLEKHM1,FBXL5,CEP170,SACS,RABGAP1L,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,HIPK3,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,USP16,TPK1,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,GNAS,FUT10,RAPGEF4,NR3C1,CIT,MFSD2A,FICD,HAS2,HMGB1,ITPKB,JAK1,KCNB1,KCND3,CAMK2N2,ARHGAP12,GPR155,CHIC1,SCAMP5,AFF1,SESN3,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,PFKP,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,VPS13C,SLC22A23,PXK,OCIAD1,RAB5B,CEP97,ATG16L1,OXR1,ZNF532,TMEM100,ATAT1,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,RUFY2,BTBD7,CMTR2,FAM126B,SON,SP2,SP4,EMC1,SMOC1,STAC2,ANKRD12,CAMTA1,WWC1,TCF4,TCF7L2,PSD3,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,DDHD1,PARD3,TPM4,RGMB,NR2C2,UBC,NSD2,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-4274:mirSVR_highEffct hsa-miR-4274:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-60 6.00E-57 3.93E-60 3.62E-59 144 556 "ARID1A,ERMN,BEND6,DISP3,LRRC7,UPRT,API5,RGS20,SLC4A4,ATP2B1,CACNA1E,CACNB2,VXN,VSTM2A,LGI1,CASC2,RAB28,TPP1,C4orf33,QKI,CNTN1,ARMC8,LETMD1,ABI3BP,BAG4,ZFP28,CLOCK,AKAP12,HAPLN1,TRIM69,ARHGEF10,SIPA1L1,VCAN,NCAN,SOCS5,DOCK4,TCAF1,DCAF8,SIRPA,PITPNC1,ZEB2,DNM1,USP3,CDON,DYRK1A,FCF1,GPR61,MRO,RABEPK,WAC,FCGRT,STRADA,FGF11,FGFR3,PRKAG2,FOXG1,CAMKK2,CELF1,TPPP3,PHYHIPL,GABBR1,CHL1,GALNT15,ILDR2,GBX2,USP19,GLUL,DCLK2,GNAO1,GRIA2,GRM7,PSIP1,ELOVL5,LRRC75A,GAREM2,NIM1K,SCIN,KCNC2,KCNH2,STMN1,NCOA7,C2orf80,PACRG,MARK3,MAT2A,MEIS1,MEST,MOBP,NAP1L3,PCDH9,A2ML1,XRN1,FTO,ING3,SPATA6,PKN2,PIGG,CNTLN,PTH1R,PEX5,RAB5B,CEP97,TMEM255A,ENOX1,SLC6A15,REV3L,SEC61A2,HSD11B1L,KCNIP2,ZNF331,ATXN2,LRRTM4,ELMOD1,TRA2B,FRMPD1,CNKSR2,BTBD3,SNRPN,PALLD,KIF21B,BDP1,GLT8D1,RBM26,TAB2,PHLDB1,VPS13A,ANKRD28,TACC1,KAZN,ALG1,ANO4,ACSL6,DMXL2,SZT2,HEY2,SYNPO2,SMUG1,RUNDC3B,SSBP2,ANKS1B,VPS35L,FZD3,KLHDC1,GAN" MicroRNA hsa-miR-24-2*:mirSVR_lowEffct hsa-miR-24-2*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.16E-60 6.49E-57 4.24E-60 3.91E-59 170 768 "SORCS1,OLMALINC,OSBPL8,BCAR3,SYT13,LRCH2,FGD2,APAF1,APC,ALS2,TNRC6C,CDC14B,IGDCC4,SPTBN4,ARHGAP5,STK33,ASTN1,RIPK1,DCAF5,LINC00906,MMD2,CACNA1E,PTBP2,CAMK2A,CAST,P2RX6,ARHGEF2,CDH10,LRRFIP1,SLC4A7,SEC31B,RBM39,SNCAIP,DZIP3,ARHGAP32,FGFR1OP2,IP6K1,ZEB2,HEPH,RHOBTB1,EXOG,DNAH9,ABI1,ATN1,EDIL3,CERCAM,RCAN2,ENPP6,ANKRD13B,RRAGB,ABCA8,FAM198B,EFEMP1,CEP78,FGF13,CAMSAP1,IQCG,ATP6V1H,ZNF605,HBS1L,GALR1,DISC1,ATP8A2,DBF4,TNRC6A,PCDH11X,LILRB4,GPD1,GPM6A,GPM6B,GRM5,TMEM25,FAM107A,ARHGAP36,ELOVL5,HSD17B1,LRRC75A,HSP90AA1,HTR5A,GAREM2,IL6ST,KCNJ10,KCNMA1,TTYH2,VWA5A,HECTD2,MDM4,MEIS1,SCAMP5,MN1,MPP2,MRPL42,CCDC80,N6AMT1,HNRNPM,NEUROD1,NPTX2,NUMA1,P2RY1,GLIPR1L2,PDE3B,GPR173,ZDHHC8,GPSM2,NLE1,LRP12,PRRX1,PPP2R5E,PRKAB2,PKN2,MDGA2,TMEM104,PTN,OCIAD1,PTPRE,RAD51D,RDX,ZYG11B,RFX4,SLC25A36,RORB,NEK11,KIAA0895L,ABCA11P,KCNIP3,ZNF568,TRAPPC13,ATXN2,IL17RB,PEAR1,FNDC3A,PEX26,SLC8A3,CCDC88A,KBTBD4,SLCO1A2,LIMCH1,DOP1A,WDTC1,ZC3H13,DBNDD2,SPTB,ZBTB43,NFASC,PBLD,ELOVL4,ADAMTS17,FNDC9,SYN2,SYP,SYPL1,TMPO,FAM124A,TP53BP2,TPM3,CHST5,PRMT8,TRIO,TRPS1,PPIL6,SSBP2,AMOT,FLRT2,GUSBP1,ZIC3,ZBTB16,ZNF154,MAP3K12,SLC17A6,FZD3" MicroRNA hsa-miR-574-5p:mirSVR_highEffct hsa-miR-574-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.58E-60 8.87E-57 5.80E-60 5.34E-59 169 761 "ASIC2,ACTN1,INTS2,ALK,AMPD3,ARRB2,INSYN2B,ATM,STX16,TTLL9,ADAM15,ADGRB2,CA4,CACNA1A,CACNB2,KALRN,PTBP2,CCK,LRBA,CCPG1,NUMBL,RCBTB2,CHN2,CASC2,MS4A7,TAOK2,EPS15L1,FAM189A2,CNR1,CPS1,SEC31B,NCOR2,CS,AATK,CSF1,MICAL2,CTNND2,ST18,CX3CR1,CYBB,DCAF8,KIAA0513,ZNF337,DGKG,ZC3H11A,SPOCK3,AASDH,EDN1,ANKRD46,PHF20L1,TMEM35A,EML1,EPB41L1,CLVS1,ZNF589,FGF11,CAP2,SYT3,AKAP3,ARFGAP2,STAU2,GABBR1,GABRA5,AHCYL1,FAM120B,ZNF559,SYT17,IGSF5,SESN1,TTBK1,GNAS,RAPGEF4,PLCD4,WIF1,ZHX1,HPSE2,HSF2,ZIC5,LRRCC1,IL6ST,SLC35G1,KCNA2,KCND1,LAMP2,MAOB,MOG,MOV10,MPP2,ERICH3,MSR1,CTNNA3,PABPC1L2A,NAP1L1,NCAM1,NEUROD2,NRGN,NTRK3,OLR1,PAK3,PDGFRA,PFKFB4,SEMA5B,PPP2R5E,CEP41,MASP1,CNNM2,CYBC1,PIGG,BDNF-AS,PYGM,RAB5B,PID1,ZDHHC14,MSANTD2,TRIM68,FIGN,RFX4,RNASEL,RERGL,TMLHE,RAVER2,CARF,ATP8B4,ATAT1,MIR124-2HG,SCN8A,FNIP1,SUPT20H,SLITRK3,SLC4A3,SLC1A6,SLC1A7,SLC6A8,SLC14A1,ATF7IP,LGI3,SMARCE1,SNAP25,KIF13A,CMTR2,SOX2,SP4,RGL1,STXBP1,NUDT10,TMEM150C,ANO4,VWA3A,ZFP90,RPGRIP1L,ARHGAP9,HHIP,PRRT1,C5orf64,STXBP4,HSPBP1,UGT8,DNAJC12,NSD2,ZNF28,CELF4,SH3GLB2,CA10,PRTFDC1,LINC00632,KAT6A,CAMK1G,ZDHHC20,CBLN2" MicroRNA hsa-miR-205-5p:TargetScan hsa-miR-205-5p TargetScan 1.96E-60 1.10E-56 7.17E-60 6.61E-59 125 419 "ARID1A,RNF157,AXIN2,PTCHD1,ABCD2,ANK2,PI16,APBB2,ARRB2,NCOA1,CALM1,CCNT1,CDC27,MAGI1,CFL2,CHN1,B4GALT6,CLTC,QKI,ARMC8,COX4I1,RTTN,ACBD5,CDC42BPB,PREPL,CRMP1,CSF1,MICAL2,CTH,ARHGAP24,ELMSAN1,MAGI2,DLG2,CPEB2,KRBA2,PHC2,HIPK3,CNNM1,FSD1L,RBM12,GPR61,ABI2,ELAVL4,CALCRL,EPB41,EPB41L1,RAB9B,ERBB4,RTN3,FGF14,PHYHIPL,JPH4,NEK6,DBF4,GLRB,CBX1,KCNMB4,IL1RAPL1,KAT7,KLF12,MIER3,HMGB1,HNRNPK,NKD1,IL6ST,KCNB1,KCND3,LSAMP,CHIC1,LDLRAD3,MDM4,MXI1,NFIA,NFIX,NRCAM,HCN1,CLDN11,P2RY1,PDE3B,PFKFB3,CDK14,PLCL1,MTRF1L,PURG,EPB41L4B,MED1,MAPK3,GRAMD1C,PROX1,BCAS3,PTPRD,PTPRG,GTDC1,LRRK2,AP1AR,NTNG1,MAGI3,BTBD3,LIMS2,SCMH1,KIF1B,CDK19,MPRIP,NSFL1C,FAM168A,PLCB1,KAZN,FAM208A,MGRN1,SATB2,CUX2,PSD3,ITGB3BP,NACC2,CADM1,FAM155A,AMOT,RBFOX3,PCDH20,MICU3,LYPD6,GDPD5,ADAMTS9,FZD3,RNF146" MicroRNA hsa-miR-603:PITA hsa-miR-603:PITA_TOP PITA 2.08E-60 1.17E-56 7.62E-60 7.02E-59 120 385 "UNC5A,PTCHD1,DOC2A,OGT,MARCH3,ATP1B3,ATP2B1,NOL4,DCAF5,CDK5R1,JAZF1,BTRC,CALM1,CDH2,CACNA2D2,FOXN3,SOCS6,HECTD1,CNR1,AHCTF1,RBM39,CSNK1G3,CTNND1,ST18,MATR3,YTHDC1,SMG7,SGSM2,DPYSL2,MAMLD1,DYRK1A,FSD1L,EGR3,GOLGA7,TMEM35A,PAN3,SYNCRIP,ANKFY1,DACH2,MEGF10,GABRB3,GAP43,DNER,PCDH17,PPARGC1A,GPR34,RAPGEF1,GRIA1,NR3C1,PSIP1,ADAMTS6,WIF1,BACH2,HLF,ZIC5,KCNA2,KCNK2,KIF5C,CAMK2N2,LDLRAD3,MEF2C,AFDN,GIT1,NCAM1,SLC11A2,GPR137C,HMGCLL1,PTPRD,PTPRN,FAM120C,TMEM255A,FIGN,RGS4,ZFHX4,PCMTD2,FBXW7,LGR4,SATB1,SCN2A,NTNG1,NLGN1,SEC31A,SMTN,SLC8A2,CPEB4,TMCC1,SOX11,SP4,LHFPL4,PEG10,COLGALT2,LARP4,NKAIN2,ERBIN,STAU1,ELOVL4,PLCB1,SYN2,TACC1,AGTPBP1,FBXW11,TBX15,TCF4,SATB2,TCF12,AP4E1,CSMD1,TRPC1,TRPS1,TSC1,EIF4ENIF1,FLRT2,ZBTB14,FMN2,TMEM198,PMEPA1,SCG2,HNRNPA3,NETO2,RNF146" MicroRNA hsa-miR-1910:mirSVR_highEffct hsa-miR-1910:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.27E-60 1.27E-56 8.31E-60 7.65E-59 163 712 "SDE2,SORCS1,PWWP2A,GPR158,ALAD,ARHGAP20,AMPD3,KIF6,ANK3,ALS2,DDO,CDK13,DYNLL1,EIF4G3,DPY19L3,BCL2L2,KALRN,PTBP2,CAMK2D,CARS,AIFM1,CDC25B,SYNPR,RAB28,TJP2,C4orf33,ARMC8,LETMD1,SNCAIP,PDE4DIP,PUM1,DCAF4,KATNAL2,DCAF8,DAPK1,BRINP1,ZEB2,COPS7A,RHOBTB1,SMG7,G3BP2,DYNC1I1,DPH1,HIPK3,FCF1,YAF2,CELSR3,EGFR,KMT5B,ING4,EMX2,ZNF549,DLC1,GORAB,FGF13,STAG2,RAPGEF6,MTHFD2,MYOZ2,C1QL1,RUNDC3A,RND1,CBX1,GRM3,MFSD2A,ZBTB45,VSIG4,RBPJ,SCIN,IL11RA,LRRTM3,KIF5A,KLC1,STMN1,MAT2A,AQP11,MEIS1,MEIS2,CD200,MT3,ZNF92,NF1,PAK3,PDE1A,PDE3B,GNG2,PIK3C2A,NLE1,PCDH18,SMIM7,MED1,PKIA,HYDIN,WDR25,PTN,PTX3,USP47,RGS10,SEC61A2,ZFHX4,GSTCD,YY1AP1,SNX22,ATP8B4,ACER3,TCP11L1,MEG3,ABCA11P,KCNIP1,SALL1,SCN2B,FOXRED1,ZFP30,ITSN1,ASAP3,FNDC3A,CNKSR2,ST3GAL3,RPH3A,SCMH1,BTBD7,SLC22A4,SMARCA4,SORCS3,ANKRD36,SNRPN,TNIK,KDM3A,GLT8D1,COLGALT2,ZC4H2,ZSCAN29,FGD4,SYNE2,C3orf70,SYP,SYT1,KAZN,ANO4,SYNE1,PCDHB6,TEK,KHDC1,CRB1,AP4E1,GPR161,CSMD1,NPL,TPM3,METTL3,TRPS1,FNDC5,MTCH1,PLPPR2,CELF4,SPIRE1,SMARCAD1,PCDH15,GOPC,TMEM63C,FBXO36,CAMK1G,CPNE4" MicroRNA hsa-miR-15a*:mirSVR_highEffct hsa-miR-15a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-60 1.30E-56 8.48E-60 7.81E-59 152 622 "ACLY,NCKAP5,KLHL32,SLC12A5,ESYT2,KIDINS220,RTL9,ANK2,LCORL,CNTNAP1,TMEM108,BCHE,BID,DST,MTMR2,C5,DDR1,KALRN,PTBP2,CAMK2D,SLC25A14,TMEM257,SEPT7,SOCS6,CASC2,NDST3,PLAA,TPP1,SLC4A8,ZFP28,CNRIP1,ANKRD44,SNCAIP,CSF3R,SIPA1L1,KATNAL2,IP6K1,DCC,ARMCX2,ELMO1,RHOBTB1,SV2A,TRAPPC9,CPEB2,DPYSL2,ABI1,DTNA,DTNB,WDPCP,TNK2,STARD3NL,ENO2,EPB41L1,LRRC17,GMPR2,WAC,FGF14,POLK,MEX3B,ZBED3,ATP6V1H,FYN,GALNT15,CAB39,ARPP21,DISC1,SULT1C4,MSTN,ARFIP1,TOX3,STMN2,FAM19A2,ATOH8,WIF1,ARHGAP36,HNMT,HTR2A,KCNA1,KCNA2,KCNK1,KIF5C,MAN2A2,AQP11,TM6SF1,MMP16,MOBP,NRBP2,MTR,NCAM1,NOVA1,GPR88,PDGFRA,PLCL1,STRN3,FAT3,PKIA,MAPK9,GRAMD1C,LRRC49,MDGA2,PLPPR1,PPP2R3C,TRIM68,RGS4,ARHGEF10L,PBRM1,RNASEL,EXD2,RAVER2,PNMA8A,PTGR2,WLS,DGLUCY,SATB1,ATXN2,LRFN5,SCN3A,SH3GL3,NTNG1,CHD9,CNKSR2,NLGN1,ABLIM3,ARHGEF40,ATF7IP,SNRPN,TROVE2,LARP4,ADHFE1,FAM208A,WASHC4,DOCK9,PCDHB4,PUM2,CRTC1,FRYL,RBFOX2,TPD52,METTL3,CCDC14,RICTOR,ZNF711,ZNF45,LYPD6,CADM2,MDH1B,PCDH15,URM1,UBE3B,KAT6A,SMIM8,ZNF248" MicroRNA hsa-miR-922:PITA hsa-miR-922:PITA_TOP PITA 2.87E-60 1.61E-56 1.05E-59 9.66E-59 120 386 "ASIC1,ACTN1,NDRG3,FMNL2,SLITRK1,AP2A1,ZNF608,PCDH19,SEMA6A,ANK3,API5,APP,ZBTB10,ATP1B3,ATP2B1,ADGRB3,BCL7A,DCAF5,CALB1,HAP1,CAMK2G,CH25H,LARGE1,DLGAP2,QKI,FHL5,LETMD1,OSBPL3,CSNK1G3,SOCS5,LONRF1,IST1,BRINP1,MYEF2,SACS,SRGAP3,G3BP2,HS3ST2,DYNC1I1,CPEB2,HIPK3,APH1A,GOLGA7,ELAVL3,PAN3,EN2,EPB41,SRRM1,ETV1,NRN1,TAOK3,CSPG5,STAG2,CAB39,BRPF3,SRRM4,KDM2B,INSM2,GPD1,GRIA2,CELF3,KLF12,BACH2,KCNC2,KCNJ3,KCNK2,MAP4,MBNL1,CHIC1,LRP1B,MEIS2,MN1,HCN1,GPR137C,GPR85,SEMA5B,NOMO2,PLEC,STRN3,PRRX1,TNPO2,MED1,PPP2R2B,PKIA,PKN2,CNNM2,PSD,RAB5B,FIGN,RAVER2,FBXW7,KCNIP1,SAFB,SCN3A,SCN4B,SMPD3,FNDC3A,LGI3,SNCA,SOX11,LHFPL4,LMO3,TAB2,ST5,PRRC2C,CAMTA1,TCF4,TCF7,DICER1,TIE1,AMACR,CADM1,UCHL1,SF1,ZNF711,REEP1,SMARCAD1,KCNAB1,VANGL2,JPH3" MicroRNA hsa-miR-519d-3p:Functional MTI Functional MTI miRTarbase 3.49E-60 1.96E-56 1.28E-59 1.18E-58 185 906 "ADAR,FMNL2,ADD1,FZD9,SORCS2,ZNF578,KIF6,SEMA7A,USP28,GPAM,CAPRIN2,ATP1B3,ATP2B1,MTMR9,BCL2L2,LDHD,ARHGEF7,MTMR3,NIPA1,FOXK1,MAP7,FMNL3,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,SLC4A7,ACBD5,ZNF385A,CPS1,CLOCK,ENTPD4,CRY2,FEZ2,SOCS5,UBXN2A,DCAF8,KIAA0513,DNAL1,YTHDC1,ELMSAN1,PLEKHM1,FBXL5,CEP170,SACS,RABGAP1L,SEC16A,USP3,SLC12A6,DPYSL2,DNAJB6,DNM1L,E2F5,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,DNAJC27,TLR7,KATNAL1,EZH1,F3,WAC,ACSL4,GTF2IRD2,POLR1B,SUCO,ANKFY1,USP16,TPK1,GAB1,GABBR1,TRAF3IP2,SALL3,ERAP1,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,RAB30,TNRC6A,CBX1,LUZP2,GNAS,FUT10,RAPGEF4,NR3C1,CIT,MFSD2A,FICD,HAS2,HMGB1,ITPKB,JAK1,KCNB1,KCND3,CAMK2N2,ARHGAP12,GPR155,CHIC1,SCAMP5,AFF1,SESN3,MXI1,NBL1,CNOT4,OCRL,PDPK1,PFKFB2,PFKP,CCSER2,ZFYVE21,TMEM38A,ZNF426,LRP12,PPARA,PRKACB,PRKCB,VPS13C,SLC22A23,PXK,OCIAD1,RAB5B,CEP97,ATG16L1,OXR1,ZNF532,TMEM100,ATAT1,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,FAM102A,CHD9,WDR37,RUFY2,BTBD7,CMTR2,FAM126B,SON,SP2,SP4,EMC1,SMOC1,STAC2,ANKRD12,CAMTA1,WWC1,TCF4,TCF7L2,GPRIN3,ZMAT3,AKTIP,NACC2,CBX5,DDHD1,PARD3,TPM4,RGMB,NR2C2,UBC,NSD2,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,FRMD6,NETO2" MicroRNA hsa-miR-133a-3p.1:TargetScan hsa-miR-133a-3p.1 TargetScan 3.53E-60 1.98E-56 1.29E-59 1.19E-58 124 414 "ADCY6,AP1B1,OSBPL8,LRRC7,PITPNM2,PPFIA2,CNTNAP1,ARHGDIA,ARRB1,CDK13,PCDHGB4,DDX3Y,BACH1,BCL2L2,JAZF1,NIPA1,MYRF,DDR1,CALM1,PTBP2,CAMK2G,RUNX1T1,ARHGEF2,CDC42,DLGAP3,CLTA,CLTC,QKI,CREB5,HAPLN1,ANKRD44,CSNK1G3,KIAA0040,CTNND1,SEC14L5,CCDC144A,NOS1AP,GAPVD1,PHF19,MAML1,IP6K1,DNAL1,ELMSAN1,DNM2,DNAJB6,ABCC9,FAM13A,PAN3,KCNMB2,ERBB2,CEP85L,ACSL4,EFEMP1,MED12L,FGF1,FGFR1,HPCAL4,CAMKK2,CELF1,DOT1L,RAPGEF6,GPM6A,GRIK3,GRM5,ATOH8,FRMD5,CELF5,RBPJ,IL6ST,KCND3,ARHGAP12,MEIS1,MEIS2,MYO9A,NFYA,NNAT,NUMA1,PCDHGC3,GPR173,BEST3,PFKFB3,PIK3C2A,KCTD15,CDIP1,PRRX1,SDK2,PACSIN1,PTH1R,PTPRD,PTPRZ1,PRRT2,RFX3,KLHL11,EXD2,C12orf49,SCN2B,CASC3,BTBD3,RIMS1,MYCBP2,GANAB,ANKRD28,ANKRD12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ARHGAP9,GPR161,GZF1,DAAM2,PITPNB,ELFN1,DOCK8,CBLN2" MicroRNA hsa-miR-505*:mirSVR_highEffct hsa-miR-505*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.57E-60 2.01E-56 1.31E-59 1.20E-58 154 640 "RALGAPA1,TTYH1,KCNH8,CSMD3,ADD2,SLC12A5,KIAA1211,ZNF608,CC2D2A,ADGRF5,MAP4K3,PKP4,APC,SLC2A11,TTLL9,BACH1,MMD2,CACNA1B,PRC1,LDB2,CDH8,TIGD7,JAM2,EPS15L1,PPT2,LY86,MFSD4A,CRMP1,TRIM69,SEC24C,MICAL2,PDE4DIP,EDRF1,FGFR1OP2,DCAF8,TMEM170A,DAPK1,ZEB2,HP1BP3,BLOC1S6,ZC3H11A,G3BP2,FAM107B,SEC16A,EXOG,DNAH9,SLC25A18,PHC2,SYT15,VPS13B,FAM198B,EFEMP1,CEP78,FER,AGAP3,NOP56,AKAP3,CINP,PDLIM5,NSG2,FYB1,HRASLS5,JPH4,ERAP1,ZNF559,DISC1,WASF3,TUBA8,TNRC6A,ZNF638,GPR12,GRIA2,GRIA4,GRM1,FAM19A2,COQ10A,FAAP20,ZNF385B,KCNK2,FGFBP3,AQP11,SYT9,XRRA1,MSR1,MT1M,MYH6,FXYD6,NELL1,NRCAM,NTRK3,OCRL,PDE3A,BEST3,SEMA5B,A2ML1,KCTD15,HMGCLL1,C11orf49,STRN3,SLC36A4,PPP2R5C,HYDIN,SYTL2,SIDT1,PIGG,CNTLN,BDNF-AS,TMEM260,PTPRG,RAD51D,SUSD4,GTDC1,NUDT11,CARF,GSTCD,ELP2,SNX22,NEK11,NCBP3,LRFN5,SCP2,CASC3,SLA,SMTN,RUFY2,SIRT2,TMEM132D,SORCS3,RCOR3,IFT122,SNCA,SNRPN,TNIK,ENKUR,KDM4C,PBLD,TRIM2,FRYL,SPX,ENHO,TIAM1,PIK3R5,TPM2,SYNPO2,PRMT8,ZNF709,PLPPR2,XRCC4,SF1,LYPD6,CA10,SLC30A4,MVB12B,AP3B2" MicroRNA hsa-miR-24-3p:TargetScan hsa-miR-24-3p TargetScan 3.93E-60 2.21E-56 1.43E-59 1.32E-58 145 569 "ADCYAP1R1,ADD2,ADD3,GRAMD1B,RNF150,LRFN2,PCDH10,OGT,ANK3,GAS7,CACHD1,KIAA1614,MARK4,CCDC74A,NCOA1,ATP2A2,ATP2B1,BCL2L2,NRP2,MTMR3,BSN,CACNA1E,HAP1,CAMK2B,CAMK2D,RHBDL1,SCARB1,ENTPD6,REPS2,MAGI1,IGFN1,CLCN3,KIAA1549L,CNTFR,AKAP5,CRY2,MROH8,CSF1R,CHD5,ERC2,RIMS2,MATR3,KIAA0087,KLHL3,GUCD1,FAM107B,EXOG,GNE,DTNA,FAM78B,GPR61,ABI2,KCTD3,EIF5,EPB41L1,REEP2,SCML2,DLC1,FCGRT,FGF11,FGFR3,AMOTL2,GABRA4,GAD1,NEK6,GBX2,PCDH17,LYVE1,NUDT21,EML4,GRIK3,RNF165,BVES,ARHGAP19,SCRT2,KCNB1,KCNK2,KIF2A,FGFBP3,GPR155,MATN3,CHIC1,MEIS2,SCAMP5,MMP16,GIT1,DBNL,MDGA1,MXI1,NEFM,NEUROD1,NEUROD2,NFIX,NOVA2,NPTX1,PDE3A,PDGFRA,MAPK7,PROX1,PIGG,PXK,PTPRD,RAB3IL1,RAB5B,GTDC1,CYB561D1,KCNIP1,SCN3A,GALNT10,FERMT1,MYO18A,DHX30,ATF7IP,MAPKBP1,MBD5,KIF21B,ARHGAP26,DDN,NFASC,NEK4,ACSBG1,MMS19,SEMA4A,PDLIM2,ACSL6,CRTC1,MTMR14,CBX5,KAT6B,RASD2,ELP5,PPIL6,FNDC5,PLEKHH2,KLC2,NDRG4,REEP1,POLR3H,EML6,DHX33,PMEPA1,GAL3ST3,NAV2,KAT6A,PIANP" MicroRNA hsa-miR-1269:mirSVR_highEffct hsa-miR-1269:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.08E-60 2.29E-56 1.49E-59 1.37E-58 142 546 "ACLY,SLITRK1,SLC12A5,SORCS1,PTCHD1,PCDH10,KCNT1,AMT,PPFIA1,IGDCC4,PCDHGB4,BACH1,RGS9,SYNJ2,C5,OSGIN2,IL33,NFS1,P2RX6,TMEM257,ZMYM4,LGI1,CFL2,NRXN1,TPP1,DNAJB5,QKI,ARHGEF6,COL4A5,AHCTF1,VCAN,SLITRK5,CX3CR1,ECE2,DAPK1,YTHDC1,ELMO1,ALKBH8,SV2B,NTM,WDR20,DLG2,RAB39B,DYRK1A,E2F6,FSD1L,ELAVL2,EMX2,VPS13B,DMTN,EXTL2,CEP78,OLFM1,SYNCRIP,NOP56,NPTN,TVP23A,CAB39,PCDH17,GGT5,LOXL3,RAPGEF4,GRIK2,LINC00839,ZHX1,IL6ST,STXBP5,CLEC18A,MAP2,AQP11,MEIS1,AFDN,MRPL42,MSR1,MSRA,NEK1,NEUROD1,PCDHGC3,PDE1A,ZNF655,C11orf49,PPP3CA,SIDT1,PXK,FAM120C,RGS4,ATP8B4,ADAL,SYNDIG1,WLS,SEMA6D,SH3GL3,MAGI3,FBXO11,SLC9A5,ELMO2,IFT122,LIMCH1,SNAP25,MBD5,ZNF415,SNRPN,UNC80,TNIK,EPB41L3,NEK4,NECAB1,TMEM150C,ALG1,TBX15,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ZFPM2,GPR161,TIAM1,TK2,ACTR6,TPM4,TRO,UGT8,ZNF70,SLC30A3,MFF,PRDM2,LRP8,ADAMTS9,NAV3,FZD3,SLC4A10,JPH3" MicroRNA hsa-miR-28-3p:mirSVR_highEffct hsa-miR-28-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.39E-60 2.47E-56 1.60E-59 1.48E-58 167 749 "SORCS1,PWWP2A,ADORA3,AP2A2,ZNF608,ABCD2,LRCH2,ANK2,PHF12,CACHD1,SHROOM2,PPP4R4,CDK13,DACT3,ATP1B3,STX16,RNF182,SCAPER,CACNA1G,C5,OSGIN2,RGN,C1orf52,CDC42,CASC2,C4orf33,SRP14-AS1,HECTD1,TMEM155,AHCTF1,FAM171B,CSF2RA,VCAN,CFAP61,PUM1,EDRF1,EARS2,LIN54,RHOBTB1,SACS,G3BP2,DMD,DTNA,DTNB,ANKRD46,PHF20L1,PLEKHA1,C8orf37,EPHA5,RASL12,EZH1,ACSL4,EFEMP1,CEP78,ZSCAN30,GORAB,FOXO3,EFCAB2,NPTN,DACH2,STAU2,FYN,PHYHIPL,GABRB1,JPH4,RAPGEF6,ERAP1,SULT1C4,LUZP2,GPM6A,RAPGEF4,GRIA2,DIDO1,GRM7,LINC00839,FRMD3,ELOVL5,HMGB1,HMGCR,HNF4G,LRRTM3,KCNJ16,KIT,LAMP2,SFXN5,SYTL4,ARHGAP12,MARK1,MBNL1,MEIS1,MRPL42,MXI1,NFE2L2,GPR85,PIK3C2A,ANLN,KCTD15,VPS13C,SYTL2,PLPPR1,PTPRG,USP47,ACSS3,CCDC40,RAD51D,NWD1,GTDC1,FIGN,SEC61A2,NUDT11,ZFHX4,SUGCT,SETD5,GSTCD,TCP11L1,RMI1,SEMA6D,ATXN7,SCN8A,FNIP1,ST6GAL1,NLGN1,ABLIM3,SLC9A5,DMRTC1,SMARCE1,SNAP25,TRERF1,FNBP1,UHRF1BP1L,CDK19,CLASP2,ZC4H2,SS18,STAU1,NEK4,DIP2A,GANAB,STXBP1,FGD4,ARHGEF9,PLCB1,MTCL1,TBCEL,TRIM2,RPGRIP1L,WDR7,SLC35G2,TEX15,FAM200B,AKTIP,SLC44A1,BHLHB9,ZFP91,HEY2,BEX4,RGMB,STXBP4,TRPC3,ZIC3,ANKS1B,EMSY,PCDH15,KCNAB1,GOPC,KLHDC1,GAN" MicroRNA hsa-miR-142-3p.2:TargetScan hsa-miR-142-3p.2 TargetScan 4.84E-60 2.72E-56 1.76E-59 1.62E-58 126 429 "CDC7,PTCHD1,ADRB2,HECW2,ALCAM,ANK2,ANK3,MAP4K3,APBB2,APC,APP,IGDCC4,CASK,ARHGAP5,ASPH,NUMB,ATP2A2,ATP2B1,ATP2B2,MTMR9,CACNA1E,CANX,RUNX1T1,ARHGEF2,CDC27,DCLK1,MAGI1,CFL2,CLTA,CLTC,QKI,MAP4K4,CNN3,HS3ST5,CLOCK,C2CD2,OSBPL3,CSNK1G3,CTNND1,PUM1,MAML1,BRINP1,ELMSAN1,JAKMIP2,CEP170,FBXO25,RABGAP1L,CPEB2,PDCD6IP,ABI2,PLXNC1,KCTD3,EIF5,ETV1,FOXO3,CELF1,FUT9,NCKAP1,PCDH17,PPARGC1A,PRRC2B,GRIA1,NR3C1,MFSD2A,HNRNPK,NEGR1,RBPJ,DOCK7,ITPKB,KCNN2,CHIC1,MEIS1,NFIA,NOVA1,GPR88,GPR137C,NLGN3,PIK3C2A,ANLN,PLCL1,PLEC,PPP2R5E,PKN2,FITM2,PROX1,QRICH1,PTPN13,MARCH1,ATG16L1,ARID4A,KHDRBS2,RDX,RFX3,KLHL11,RIC8B,ATXN1,MRAS,HSPA4L,FBXO11,RUFY2,CCDC88A,BTBD7,CPEB4,PDZD2,ERC1,CDK19,RAP1GAP2,NFASC,DIP2A,PHLDB1,GSE1,ANKRD28,CAMSAP2,CRTC1,GPRIN3,HHIP,DDHD1,LRRC8A,RBFOX2,MTCH1,KLC2,RICTOR,ANKS1B,CADM2,EVI5,FXR1" MicroRNA hsa-miR-155:PITA hsa-miR-155:PITA_TOP PITA 5.42E-60 3.05E-56 1.97E-59 1.82E-58 107 304 "FMNL2,ADD3,SORCS1,ABCD2,FAM135A,C6orf89,LCORL,MAP4K3,ASTN1,DDX3Y,ATP2B1,ATP2B3,KSR1,REPS2,CCPG1,CLCN3,CSF1R,SOCS5,BOC,TOMM20,RHOBTB1,G3BP2,DYNC1I1,NR1D2,MBNL2,LPAR6,KCTD3,PLEKHA1,C3orf18,EN2,FOXO3,SGIP1,CAB39,RAB30,GNAS,KIF3A,MIER3,IGF1,JAK2,KCNA1,KCNN3,SMAD1,LRP1B,MEIS1,MITF,ZC3H12B,NFIA,NFIX,NOVA1,PCDH9,PDE3A,GPR85,PIK3R1,CCSER2,XRN1,STRN3,RC3H2,CEP41,PKIA,PKN2,ELOVL2,PTPRD,PLEKHB2,ARID4A,SLC6A15,SEC61A2,SATB1,ELMOD1,CHD9,FBXO11,SLA,SLC1A3,BTBD3,SEPHS1,SLC20A2,CPEB4,SMARCA4,PALLD,SOX1,SOX11,HECW1,TAB2,NKAIN2,RGL1,SYPL1,CAMTA1,WWC1,TCF4,SATB2,TRIM2,TCF12,SIRT1,TRPS1,SGK3,ZIC3,CELF4,ZBTB38,SMARCAD1,WNK1,SCG2,NAV3,PAK5,KAT6A,HNRNPA3,FXR1,ST8SIA2,SLC4A10" MicroRNA hsa-miR-875-5p:mirSVR_highEffct hsa-miR-875-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.65E-60 3.18E-56 2.06E-59 1.89E-58 159 683 "KCNH8,CCDC85A,CDC7,SORCS1,RNF150,ESYT2,ALCAM,PARG,EPB41L5,UPRT,PPP4R4,ADGRB3,NRP2,LRBA,CLU,FHL5,AKAP6,BTF3L4,SLC4A8,ABI3BP,RCHY1,ACBD5,TRIM69,TENM4,PHF14,NRSN1,USP6NL,CCDC144A,CYBB,HDAC9,GAPVD1,RIPOR2,DGKB,ZEB2,COPS7A,DDX46,FAM107B,DYNC1I1,DTNA,E2F5,RASGRP1,FRY,PHF20L1,EGFR,ELAVL2,EPHA5,EYA1,FAM198B,SH3YL1,ACSL4,TAOK3,CEP78,CHST15,NELFCD,ATP2C1,ABLIM2,STAG2,MEGF11,GABRA1,NEU3,GLRB,GLS,RNF165,WIF1,HPS5,NEGR1,LRRCC1,ITGAV,NCOA7,AQP11,SYT9,MDM4,MKLN1,MOBP,ZNF680,SCG3,NAP1L2,NFE2L2,NUCB2,IGSF11,GPR88,CLDN11,SNTG1,PDE1A,PDE4D,PDYN,ABCB1,RETREG1,PMP2,STRN3,SH3KBP1,TATDN3,PRKACB,PRKCB,MASP1,CNTLN,PTN,OCIAD1,RASGRF2,ERI2,SETD5,RAVER2,RPE65,SPIN3,ATP8B4,LRRK2,LGR4,CCDC112,SALL1,SCP2,MRAS,FAM102A,PPM1E,FHOD3,SYBU,PPP4R3A,LRRC55,SLC15A2,SMARCE1,RCOR3,LIMCH1,PDZD2,SP2,MCF2L2,RBM26,SRPK2,TROVE2,ITPRID2,SSTR1,CEP68,FGD4,SYNE2,SYPL1,MTCL1,DDHD2,ATMIN,SATB2,TCF7L2,SYNE1,NSD1,SIK3,ZFPM2,AKTIP,GZF1,TIAM1,MTMR14,ASXL3,TLL2,C5orf64,SYNPO2,TRIO,ANO5,WIPF1,PCDH20,ZNF74,FSTL5,LRP8,SMIM8,PHTF2" MicroRNA hsa-miR-3160:mirSVR_highEffct hsa-miR-3160:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.96E-60 3.35E-56 2.17E-59 2.00E-58 185 909 "ACADM,ABHD6,PWWP2A,KIAA1211,HECW2,NME5,PLA2G6,LRRC7,BCAR3,OGT,PPFIA1,MIER1,PDE8B,CAPRIN2,BCS1L,BLM,SGCE,CACNA1G,KALRN,CAMK2D,ARHGEF25,INA,CDH18,LGI1,CFL2,QKI,HECTD1,CHD1L,NCOR1,CS,PHACTR3,RIMS2,RUBCN,EDRF1,CCDC144A,GPRASP1,GIT2,TMEM130,LYPD1,NTM,GRIN3A,DMD,DPP6,ECM2,DNAJB6,ABCC5,DNM1L,EDIL3,SEMA3D,GOLGA7,PAN3,FABP7,FCGR3A,FDFT1,FGF11,SEMA4D,CGREF1,PHYHIPL,GABRA2,GABRB1,IP6K3,GAP43,ERAP1,DISC1,INPP5K,DNER,ADAM28,LYVE1,GLRB,PCDH11X,GNG3,GNG4,GPD2,EML4,DIDO1,GRIK3,GRM7,ADAMTS6,GUCY1B1,MAEL,HNRNPK,ZNF546,C2orf72,PLD5,IGSF1,INPP5B,KCNH2,KCNJ16,KCNK1,IPO5,MAT2A,TM6SF1,XRRA1,CD200,MSR1,NELL1,NFE2L2,NODAL,DNHD1,LRIT2,SLC11A2,OCRL,OXTR,ZNF827,PCDH9,PCSK2,PDE3B,PDE4D,CDK14,HERC2P3,ZNF655,ST8SIA5,PRIMPOL,PMP2,POLR2F,POU3F2,MED1,PRKAB2,CNNM2,WDR25,PXK,PTPRG,MARCH1,TMEM255A,SLC6A15,RFX2,RIT2,NUDT11,CARF,SNX22,NEK11,RPL15,FOXRED2,ATXN2,ATXN7,ASRGL1,NTNG1,SLA,RPH3A,PEX26,DHX30,RUFY2,SLIT1,INTS9,TTC17,UNC80,KDM3A,CLUAP1,ENKUR,IDI2-AS1,KIF1B,ATP10B,POGZ,TTBK2,ACSBG1,VPS13A,DNAJC9,EHBP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIK3,SIRT1,ITGB3BP,AP4E1,ZFP91,C5orf64,RASD2,TPM4,CADM1,RPL7L1,ETNPPL,ZNF540,PLPP4,ANKS1B,CA10,PRDM2,LRP8,RNF103,PDSS2,CASC15" MicroRNA hsa-miR-19a-3p:Functional MTI Functional MTI miRTarbase 6.39E-60 3.59E-56 2.32E-59 2.14E-58 145 571 "SDE2,MTUS1,HECW2,PCDH10,GPAM,USP37,MIER1,CAPRIN2,DDX3Y,STX16,BCL7A,JAZF1,NIPA1,CALM1,PTBP2,EVI5L,CFL2,ZFYVE9,QKI,ARMC8,BTF3L4,ACBD5,CLOCK,HDAC4,RASSF2,LONRF1,GIT2,DBN1,DCC,SPATA2,CEP170,KLHL3,G3BP2,MTX3,WDR20,DPYSL2,HIPK3,TMTC1,MBNL2,PLXNC1,CERCAM,ERBB4,VPS26C,TLR7,KATNAL1,WAC,ACSL4,PRMT5,MED12L,CAMSAP1,NPTN,CAB39,ZMYND11,RAPGEF6,AHDC1,MALT1,TNRC6A,PRUNE2,RAPGEF4,GRB10,CIT,KIF3A,ELOVL5,C5orf24,ZIC5,CLVS2,KIT,ARHGAP12,MBNL1,KITLG,AFF1,ZNF680,SESN3,CCDC80,MYCN,IDNK,NF1,NFIA,CNOT4,OCRL,PDE4A,CCSER2,PKM,PURG,TNPO2,SH3KBP1,PPARA,PPP2R5E,PRKACB,DEF8,PTPRB,PTPRG,RAB5B,ATG16L1,RBBP8,KLHL11,CLIP1,SATB1,ATXN1,ATXN7,SOX6,SGK1,FAM102A,CHD9,FNDC3A,EPN2,SLC6A8,NAPB,BTBD7,KIF13A,ZNF423,SPART,POGZ,SMOC1,MPRIP,RGL1,DIP2A,PRRC2C,VAMP1,ARC,ANKRD12,CAMTA1,EXOC7,CAMSAP2,ALG1,ATMIN,DMXL2,TF,DICER1,ZMAT3,NACC2,CBX5,TNFRSF1B,WBP2,TRPC3,ZNF138,ZNF154,ZFAND5,WNK1,PMEPA1,MFF,STOX2,WNK3,FXR1,FRMD6" MicroRNA hsa-miR-628-3p:mirSVR_highEffct hsa-miR-628-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.47E-60 3.64E-56 2.35E-59 2.16E-58 176 829 "ACTN2,KDM5D,KLHL32,ADD3,KIDINS220,KCTD16,CEP126,FAM135A,LRCH2,ANXA7,ARNTL,RGS20,DPY19L3,BMPR1B,SYNJ1,BTK,OSGIN2,CALB1,PTBP2,ZNF501,LRBA,SEPT7,CLGN,COG1,ABCG2,CNN3,SLC25A27,COL9A1,BTF3L4,SLC4A7,ACBD5,CREM,IPCEF1,CTH,GAPVD1,RIPOR2,FRMPD4,LIN54,TOMM20,ZEB2,DYNC1I1,EDNRA,FRY,FSD1L,YAF2,TENM1,VPS13B,ENPP6,RTN3,EXTL2,SH3YL1,EFEMP1,CEP78,GORAB,POLK,SYNCRIP,SMC2,TPK1,ATP6V1H,KHDRBS3,CHL1,KIAA1841,GHR,PCDH11X,HTATSF1,GNAS,GPM6A,NUDT21,RABL2A,FRMD5,MIER3,NEGR1,ZIC5,USP54,SLC35G1,KCNN2,KIF5C,KLRC3,STXBP5,LAMP2,SYTL4,HECTD2,PACRG,SYT9,CHIC1,MEF2C,MEIS1,ZNF680,MTTP,NDUFA5,PCDH9,PDE4D,PDGFRA,SERPINE2,EPB41L4B,PPM1B,CRLS1,PPP3CA,PPP3CB,PRKACB,MAPK10,VPS13C,CNTLN,OCIAD1,PTX3,PEX2,OXR1,ZYG11B,RET,SEC61A2,PBRM1,ALG9,CARF,CCDC102B,ATP8B4,GLDN,ADAL,ABCA11P,HUNK,ATAT1,RTN1,SCG5,ZFP30,PPP4R3A,SLC8A1,ATF7IP,TET1,TTC17,CMTR2,EMC1,MYCBP2,SPTB,NPAS3,SRPK2,ZC4H2,LARP4,NKAIN2,ELOVL4,SEPT3,SYT11,SYT4,DDHD2,SATB2,WASHC4,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CCDC173,HHIP,BHLHB9,STXBP4,TRPC1,HIRA,HEPACAM,RPL7L1,FAM155A,UBE2H,ZNF708,ZNF17,LYPD6,FSTL5,SPIRE1,URM1,KCNAB1,PAK5,FBXO36,RNF170,KLHDC1,NETO1,RNF146,SENP7" MicroRNA hsa-miR-323a-3p:TargetScan hsa-miR-323a-3p TargetScan 6.89E-60 3.87E-56 2.50E-59 2.30E-58 116 362 "ADCY6,GRAMD1B,KIAA1211,OSBPL8,FAM135A,C6orf89,PHF12,ALS2,APP,INSYN2B,NOL4,NRP2,FUBP1,MTMR2,CACNA1G,LDLRAD4,CABP7,KALRN,MAP7,RUNX1T1,CERS5,CBFA2T2,C1orf52,CDC27,MAP4K4,NIPBL,FHL5,NRG2,NSL1,CDC42BPB,NCAN,APPL1,PUM1,DOCK4,BRINP1,ELMSAN1,DNAJC6,JAKMIP2,HP1BP3,KLHL3,G3BP2,ARNT2,RCAN1,GNE,HIPK3,EFNA3,ABI2,EGR3,KCTD3,ELAVL2,DCTN4,EIF1,EPHA5,KCNMB2,ENPP6,ERBB4,SEC23B,FUT9,MPP6,GAD1,SALL3,NEK6,FAXC,PCDH17,GHR,MSL3,GPR22,GRM7,MFSD2A,MAP4K5,HMGCR,HNRNPK,IGF1,PLD5,LRRTM3,KCNB1,KCND3,CLVS2,KCNQ3,KITLG,MITF,MKLN1,NASP,NFIA,NFIX,PCDH8,PDE4B,PDE4D,CDK14,GPSM2,LRP12,CRLS1,EML5,RAB5B,RAP1GDS1,ENOX1,RFX3,CSRNP3,FNIP1,ARX,CPEB3,BTBD3,CPEB4,MBD5,MYT1L,KDM3A,RAP1GAP2,DDN,LMO3,LRRC4,ANKRD28,ATP11A,FAM189A1,CBX5,CSMD1,JPH3" MicroRNA hsa-miR-1302:mirSVR_highEffct hsa-miR-1302:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.91E-60 3.88E-56 2.50E-59 2.31E-58 170 777 "RALGAPA1,KCNH8,FMNL2,GALNT13,ADD3,BRAP,PWWP2A,LRRC7,UPRT,AQP6,ATM,ATP2B2,N4BP2L1,NOL4,ADGRB2,NRP2,DST,ARHGEF7,SCAPER,CALB1,INA,SYNGR3,CD38,LRRFIP1,CDO1,ABI3BP,ZFP28,CHD1L,GDA,CS,FEZ1,RUBCN,GPRASP1,RIPOR2,EARS2,ZBTB24,MYEF2,HP1BP3,ALKBH8,RAB39B,DYNC1I1,SLC12A6,ABI1,GNE,YAF2,APH1A,EPHA5,EPHB1,SRRM1,NCALD,F5,ARMCX1,TUBA1B,PTK2B,FCGR3A,FER,FGFR1,CAMSAP1,POLK,SUCO,SLC37A3,MEGF10,GABRA5,GABRG2,ARPP21,IQGAP2,DISC1,GLS,TNRC6A,ZNF638,KDM2B,LUZP2,PRUNE2,GRM8,MAEL,MIER3,NKD1,KIAA1755,DIPK1A,ZNF385B,LRRTM1,STMN1,LIG4,HECTD2,MBD1,MBNL1,SYT9,TM6SF1,KITLG,MOBP,NEXMIF,NELL1,NFIA,NME4,VWA2,CNOT4,NOVA1,NTRK2,PCDH9,BEST3,SNX10,PLCL1,SLC36A4,MED1,SAMD9,VPS13C,OCIAD1,PYGM,OXR1,RGR,GSTCD,GLDN,ABCA11P,HUNK,NCBP3,LRRTM4,SH3GL3,NTNG1,HKDC1,MAGI3,FBXO11,SLITRK3,SYBU,SEC31A,ABLIM3,ZNF365,FAM81A,ATF7IP,ZNF667,INTS9,RCOR3,RIMS1,MAPKBP1,ANKFN1,KIF1B,CDK19,TAB2,MPRIP,SULF2,SEPT3,FAM168A,VAMP1,PLCB1,SYT1,FAM208A,TCEA1,ACSL6,WASHC4,SYNE1,SLC19A3,OBSL1,DICER1-AS1,GZF1,TPM3,METTL3,TRPS1,RUSC1,TSC1,TMEFF2,VSNL1,AGMO,TMEM237,MAP3K12,XKR7,SIGLEC10,SNX27,FAM47E,C12orf4,DOCK8,ST7" MicroRNA hsa-miR-450b-3p:mirSVR_highEffct hsa-miR-450b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.25E-60 4.07E-56 2.63E-59 2.42E-58 143 556 "ADCY6,KIAA1211,BEND6,OLMALINC,KLHL13,ADGRF5,AMT,PKP4,USP37,PLA2G4C,ATP2B1,CFLAR,CLDN10,AIFM1,C1orf52,LGI1,SYNPR,KMT2C,IGLON5,SUMF2,CP,CHD1L,FAM171B,ANKRD44,SNCAIP,SLITRK5,GPRASP1,FRMPD4,ARMCX4,JAKMIP2,ELMO1,HP1BP3,COPS7A,WDR20,EXOG,GRIN3A,DMTF1,FARSB,EDN1,FAM135B,EDN3,SGK2,FCF1,APH1A,GOLGA7,DCTN4,ENO2,SRRM1,CDKL3,F5,F8,FABP7,FDFT1,KAT8,POLK,GABRG2,AHCYL1,B4GALNT1,GAP43,GLS,MAP7D2,GPM6B,RAPGEF4,GRIA1,GRIA4,RFFL,PRDM5,GRM7,FAM19A2,FAM222A,FRMD3,HLF,HNF4G,HNMT,LRRC75A,BRINP3,KCNJ3,KCNMA1,ZNF667-AS1,MEIS2,SRSF12,MEST,MYO7A,CNOT4,NOVA1,PCSK5,PCDH18,PPP2R5E,RASGEF1B,PRKAR1B,MAPK10,GRAMD1C,HYDIN,PTPRE,PTPRG,OXR1,HKR1,RFX4,SEC61A2,PBRM1,SUGCT,C12orf49,ADAL,FAM182A,MIR124-2HG,SCN8A,SLC30A10,SEC14L1,NLGN4Y,NTNG1,CCDC92,WDR47,INTS9,SMARCE1,RCOR3,LIMCH1,UNC80,SOX2,KDM4C,RAP1GAP2,SPART,POGZ,INKA2,ANKRD28,TACR1,SATB2,RNF175,AP4E1,ASXL3,HEY2,TNFRSF1B,TPM3,SYNPO2,TUBB1,VLDLR,ZNF708,MICU3,ZNF154,INTS3,CA10,PRDM8,PCDH15,FXR1" MicroRNA hsa-miR-377:PITA hsa-miR-377:PITA_TOP PITA 7.52E-60 4.22E-56 2.72E-59 2.51E-58 130 459 "ARID1A,USP31,OSBPL8,MADD,MARCH3,NCOA1,NRP2,DST,JAZF1,BSN,WASF1,CACNA2D1,CACNB2,SPAG9,USP6,DLGAP2,CACNA2D2,SRSF11,FOXN3,CHM,B4GALT6,CNR1,AKAP6,DZIP3,APPL1,PUM1,SPOCK2,DNAJC6,ZEB2,ELMO1,C2CD2L,ALKBH8,CDON,PHC2,ABI2,EGR3,PCOLCE2,EML1,EPB41,KCNMB2,ERBB4,KATNAL1,CAP2,AFF2,NBEA,SALL3,IQGAP2,SESN1,PCDH17,PPARGC1A,SPIN1,PCDH11X,TDRKH,EML4,TPPP,PTPRT,RNF165,NXPH3,NEGR1,IGF1,C5orf24,ZIC5,IBA57,JAK2,KIF2A,KLC1,IPO5,CAMK2N2,LMO1,NCOA7,MITF,MSI1,NKX2-2,NOVA2,SLC11A2,PRTG,PDE4D,GPR85,GNG2,PFKFB3,GDAP1L1,CAMKV,TRHDE,LRP12,WBP1L,PTPRB,RDX,SLC6A15,RET,RIC8B,SETD5,PCMTD2,CSRNP3,ATXN1,ATXN7,SGK1,NLGN1,WDR37,NAPB,CPEB4,MBD5,SOX11,ARHGAP26,SRPK2,ITPRID2,STAU1,PLCB1,SYT4,CAMTA1,TAL1,TBL1X,RPGRIP1L,TCF12,PUM2,FRYL,TIAM1,ASXL3,AMACR,EIF4ENIF1,OSBP2,NSD2,TCEAL7,CELF4,REEP1,MVB12B,KAT6A,PHTF2,VANGL2,NETO2,SLC4A10" MicroRNA hsa-miR-4270:mirSVR_highEffct hsa-miR-4270:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.06E-60 4.53E-56 2.92E-59 2.69E-58 177 839 "ASIC2,CLK4,BRAP,KIAA1211,PTCHD1,LRFN2,GPR158,KIAA1324,LRRC7,SRPX,LRFN1,OGT,SUGT1P4-STRA6LP-CCDC180,PARG,DACT3,CADM3,CFLAR,LURAP1,NGB,RUNX1T1,ENTPD6,MAGI1,PPT2,KIAA1549L,NRXN1,TPP1,CLTA,FBXO7,QKI,LY86,CNTFR,SUMF2,BTF3L4,MYRIP,HS3ST5,ZNF385A,CRYM,PHF14,RIMS2,ECE2,DCAF8,PHF19,CEP170,TMCC2,ZNF582-AS1,DLG2,HS3ST2,NR1D2,DPP6,ABCC5,ANKRD46,SYT15,C8orf37,EPHB1,DENND4A,VPS26C,RTN3,PRMT5,ZNF589,CAMSAP1,NOP56,NELFCD,CGREF1,KBTBD12,AP4B1,GABRG2,IGSF5,TUBA8,GFAP,GHR,PPARGC1A,STARD3,CBX1,MAP7D2,INSM2,GNAL,FUT10,CCDC184,LPAR4,RABL2A,SOX21,HNMT,MSL1,FAM95B1,LRRC25,RBPJ,OLFM3,KCNJ3,PAXBP1,SYTL4,VWA5A,NCOA7,MAOB,MAT2A,MBD1,PPM1L,CD200,ERICH3,PABPC1L2A,BEX5,NBL1,NOVA1,NTRK3,OMG,PAK3,PCSK2,CDK18,BEST3,FAM98B,CAMKV,PCDH18,EXOSC10,SEPT4,MED1,PPP1R1A,PRKCG,KLK6,GDPD2,MDGA2,TMEM260,RAP1GDS1,DBX2,FEZF2,TRIM68,PRRT2,RIC8B,SETD5,CARF,CYB561D1,NEK11,FBXW7,ACER3,RTKN,KCNIP2,ZNF331,LRFN5,PEAR1,CASC3,ITSN1,BCAN,ST3GAL3,SMTN,PKNOX2,CCDC88A,ELMO2,SNAP25,TNIK,SP2,SPP1,RAP1GAP2,STOX1,VPS13A,SYN2,ROBO3,MLST8,SATB2,ZEB1,WDR7,HHIP,AKTIP,SLC44A1,MTMR14,ERCC6L2,SEZ6L,NEIL2,TSN,SSBP2,DNAJC12,FLRT2,LAMP5,EMSY,LMAN2L,HPS4,DOCK8,FBXO36,DPF3,LAS1L" MicroRNA hsa-miR-506:mirSVR_highEffct hsa-miR-506:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.31E-59 7.34E-56 4.73E-59 4.35E-58 204 1091 "AXIN2,ERMN,PLEKHH1,SLC44A5,ZNF608,OSBPL8,CC2D2A,TAOK1,SEMA6A,ZNF687,LCORL,ANXA7,PPP4R4,ASPA,CAPRIN2,DDX3Y,ATP1A1,ATP2B2,BCL7A,NRP2,MYRF,KALRN,PTBP2,USP2,TMEM257,CDH2,LRRFIP1,LHX2,TJP2,QKI,CNTN1,AKAP6,RTTN,CHD1L,CLOCK,ANKRD44,SNCAIP,VCAN,SOCS5,CTNND1,EDRF1,HDAC9,GAPVD1,DAPK1,FBXL5,RHOBTB1,SPOCK3,G3BP2,EXOG,CPEB2,DTNA,DYRK1A,E2F5,SNX29,EDNRB,HIPK3,SEMA3D,FSD1L,EPS8,ADGRV1,CEP78,ZNF589,FER,PRKAG2,SUCO,SYNCRIP,POMT1,ZNF605,NEK6,IQGAP2,DISC1,KIAA1841,ARFIP1,GDF9,PCDH17,GHR,CRCP,RAB30,GLRB,KIAA1958,GPT2,GPD2,CECR2,GRIA2,GRIA4,GRID1,NR3C1,GSN,LINC00839,KAT7,AP4S1,IRAK3,MYLK2,IL6R,ITGA7,SLC35G1,KCNK2,KIF2A,KLC1,LIMS1,PAXBP1,VWA5A,HECTD2,ASPRV1,MARK1,MAT2A,MBNL1,POC1B,MITF,AFDN,BCO1,MSRA,NAP1L3,NFE2L2,NME4,NRCAM,NUMA1,KCNK10,PCDH8,PCDH9,PDE4B,GNG2,GDAP1L1,SSH1,PIK3C2A,RETREG1,SMOX,PRRX1,ING3,SH3KBP1,PPP3CB,PKN2,MDGA2,MTMR10,SPDL1,TMEM260,PTPRB,OCIAD1,PTPRD,FAM120C,C1orf109,PTPRZ1,ACSS3,RAD17,RFX4,RGS12,SLC25A36,SUGCT,GSTCD,CCDC25,ELP2,ATP8B4,PRR5L,SOX8,RYR1,RYR3,SEMA6D,SCN7A,CASC3,GALNT10,SGK1,SH3GL3,NTNG1,SHC4,MAGI3,SLITRK3,FAM81A,ATF7IP,TET1,ZKSCAN3,ZNF667,SMARCE1,TTC17,LIMCH1,PALLD,ZCCHC24,BDP1,ITPRID2,KANK1,PLCB1,SYPL1,ANO4,PCDHGA11,PCDHA5,DDHD1,TMOD1,C9orf85,TUB,UBE3A,USP1,WIPF1,CLDND1,ETNPPL,FSTL5,EML6,ZNF189,SMARCAD1,WNK1,EVI5,SEMA3B,PHTF2,CASC15,JMJD1C,FXR1" MicroRNA hsa-miR-575:mirSVR_highEffct hsa-miR-575:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-59 7.48E-56 4.81E-59 4.43E-58 159 687 "RBM10,CSMD3,PWWP2A,SLC44A5,KLHL13,SPOP,ANK3,PHF12,PKP4,EPB41L5,ALS2,AQP4,MADD,TMEM263,CHRD,ATP2B1,TTLL9,DST,SYNJ1,OSGIN2,PTBP2,CANX,SPAG9,CBLN1,MTMR7,CBFA2T2,AP4M1,DCLK1,MAGI1,CFL2,CNOT8,BTF3L4,LETMD1,COL9A3,RNF14,CSNK1G3,SLITRK5,GAPVD1,TOX,DAPK3,DBN1,C8orf34,DDX46,SNAP91,SACS,HS3ST2,GOLT1B,FAM135B,EDN3,PHF20L1,EGFR,EIF1,EN2,EPHB1,IGSF6,RCSD1,FABP7,DLC1,RACK1,TOMM40L,MED12L,POLK,SEC23B,NELFCD,CINP,DACH2,AP4B1,GABBR1,GABRA2,HBS1L,ARPP21,GALR1,KIAA1841,IGSF5,GCNT2,TUBA8,DBF4,EML4,PCLO,ATP2B1-AS1,GRIA2,GRM7,MFSD2A,GABARAPL2,CELF5,KCND2,KCNQ3,CREG2,CAMK2N2,HECTD2,ZFYVE27,AQP11,MBD1,SYT9,MEF2C,MOG,ZNF680,NFE2L2,SNTG1,PDE1C,MAPKAP1,SEPT4,NXPH1,PPARA,LRRN3,PTPA,MAPK9,GRAMD1C,HYDIN,BDNF-AS,FAT4,DBX2,RDX,RFX3,RFX5,RGS12,GSTCD,ELP2,NEK11,EPHA10,LRFN5,LRRTM4,FAM19A1,PRCD,FOXRED1,SCAF8,CHD9,FAM81A,RAB3GAP1,ZKSCAN3,ZFP1,ZNF667,LMBRD1,TNIK,ZSWIM8,ZC3H13,STOX1,MTCL1,ROBO3,FBXW11,ANO4,PUM2,FRYL,TMOD1,PRMT8,TTTY15,AMOT,UGT8,ZNF708,TMEM237,EML6,SYNC,MEIS3,WNK1,CADM2,WNK3,PARP11,FAM13C,ACTR3B" MicroRNA hsa-miR-200c*:mirSVR_highEffct hsa-miR-200c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.00E-59 1.12E-55 7.20E-59 6.63E-58 140 537 "ARID1A,KLRC4,GALNT13,BEND6,NME5,HFM1,SPOP,USP35,SRPX,PCDH10,CDC42BPA,DGKZ,PPP4R4,ZSCAN18,NUMB,ATP1A2,NOL4,CA8,RUNX1T1,ZNF501,INA,SLC16A4,CDC27,LGI1,ZBED5,KMT2C,COL9A3,C2CD2,CRHBP,VCAN,SOCS5,APPL1,KATNAL2,IST1,PITPNC1,ZEB2,RHOBTB1,ABI1,DTNA,HIPK3,FRY,FAM13A,PHF20L1,EML1,EPB41,ANKRD13B,NCALD,TMEM74,EYA1,ZNF585B,DLC1,SYNCRIP,OGA,MTHFD2,DISC1,PCDH17,KDM2B,GNAO1,LILRA1,PRLHR,TOX2,C1orf94,ZDHHC15,OPALIN,INSM1,ITPKB,KCNJ16,KCNN2,KIF2A,KIF5C,STXBP5,LMO2,HECTD2,MAT2A,MBNL1,EFHB,SHC3,MEF2C,MEIS1,SRSF12,KITLG,MID1,AFDN,MTTP,IDNK,GPR137C,PAK3,CNTN3,PCDH8,PDE4D,ZNF655,FAM218A,PRPSAP2,VPS13C,FAM184A,HKR1,CRTAC1,TTLL7,CARF,RORB,PCMTD2,ZNF568,CSRNP3,SFPQ,SH3GL2,NTNG1,NUBPL,ZNF365,SNRPN,MYT1L,SAMSN1,DIP2A,ARHGEF9,PLCB1,SYT4,C12orf76,CAMSAP2,TBCEL,TCEA1,SATB2,DOCK9,USP32P1,SIRT1,CRB1,TMOD1,TMPO,RUNDC3B,TRPC3,TMEFF2,SGK3,AMOT,MEAF6,GUSBP1,TRIM9,ZFAND5,EMSY,PRDM2,PHTF2,MSRB3,SLC4A10" MicroRNA hsa-miR-548q:mirSVR_highEffct hsa-miR-548q:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.00E-59 1.12E-55 7.20E-59 6.63E-58 140 537 "ABHD6,NCKAP5,ADD2,GRAMD1B,ADORA3,RNF150,ZNF608,SPARCL1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,GPAM,STK33,ADGRB3,BARD1,SEC11C,CALB1,KALRN,CBR1,LDB2,SEPT7,CDH8,ZMYM4,RCBTB2,KIAA1549L,CLTC,ACBD5,CHD1L,SNCAIP,SEC24C,ARHGEF10,MICAL2,OSBPL3,RIMS2,BOC,ARHGAP32,RIPOR2,TOMM20,IP6K1,ZEB2,WDR20,DNAH9,ABCC5,EBF1,RBM12,COPS4,PAN3,MFSD10,EPB41L2,SIRPB1,GMPR2,F5,ZSCAN30,KAT8,BAIAP2,NOP56,NBEA,STAU2,OGA,ZMYND11,B4GALNT1,GHDC,DISC1,ATP8A2,GCNT2,GLS,TNRC6A,PRLHR,GPR19,BTN2A1,RNF165,SMAP1,MSL1,BRINP3,DIPK1A,KCND2,KCNJ3,KPNA5,CYP27C1,MARK1,MAT2A,NHLH1,NTRK3,ZNF827,GNG2,BEST3,ZNF655,PLP1,PCDH18,PRIMPOL,ING3,POU3F2,PKN2,MAPK9,RET,MORC4,SEC61A2,RNASEL,SETD5,SYNDIG1,ABCA11P,ST6GALNAC6,CLIP1,TMEM156,DGLUCY,FNDC3A,ST3GAL3,PAAF1,SLC1A3,PPP4R3A,SMTN,SLC12A2,ZSWIM8,RBM26,C11orf87,SRPK2,LRRC4,STAU1,ZSCAN29,ADHFE1,CAMTA1,EHBP1,ITGB3BP,FAM124A,R3HDM1,C5orf64,C9orf85,TPM4,METTL3,LMF1,ZNF781,ZNF711,ZNF19,KCNT2,TRIM9,LYPD6,LAMP5,CA10,SMIM8,PHTF2,CERS6" MicroRNA hsa-miR-3146:mirSVR_highEffct hsa-miR-3146:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-59 1.22E-55 7.86E-59 7.24E-58 158 681 "ADD3,KIDINS220,GPR158,TXNDC16,ABCD2,CARNS1,DPP10,APC,APP,MIER1,SPTBN4,ARRB2,ZNF583,AZGP1,BCHE,SCAPER,CACNA1D,CALB1,THSD7A,CBR1,REPS2,MAGI1,CNOT8,CPNE6,ZFYVE9,DGCR9,TJP2,QKI,CNN3,FAM149A,COL4A5,MFSD4A,GDA,PDE4DIP,GREB1,HDAC9,CENPL,KCTD8,C8orf34,HP1BP3,KIAA0753,NTM,G3BP2,GRIN3A,DNAH9,CASP8AP2,DTNA,ECM2,ABCC9,GOLT1B,E2F5,EDNRB,ANKRD46,GOLGA7,C8orf37,CALCRL,DCTN4,CEP85L,F8,CAMSAP1,POLK,SEC23B,DCTN2,CAMKK2,NSG2,OGA,PHYHIPL,GALC,ARPP21,DISC1,KIAA1841,GHR,MAP7D2,GPD2,GPR34,GRM7,SOX21,LRRTM1,SLC35G1,OLFM3,KCNC1,KCNH2,CLVS2,KCNK2,KLRC2,CYP27C1,MAP4,MAT2A,KCTD6,MRPL42,ADAM22,RSPO2,MYO9A,NCF2,SLCO1C1,NOS1,SLC11A2,NUMA1,OCRL,P2RY1,JAKMIP1,HMGCLL1,PRKCB,HYDIN,CNTLN,PLPPR1,BDNF-AS,TMEM255A,VEPH1,GTDC1,RIC8B,PBRM1,RPRD1A,RAVER2,SFPQ,FBXO11,CNKSR2,SLA,SLC1A6,DHX30,RUFY2,CDK5RAP2,PALLD,COLGALT2,ITPRID2,NUDT10,UNC5D,ADGRL3,TCEA1,EHBP1,ZEB1,TRIM2,TCF12,HHIP,ZFP91,ERCC6L2,FAM124A,WBP2,TRIO,TRPC1,TMEFF2,UBE2H,AMOT,UGT8,TBC1D15,WIPF1,CLDND1,XRCC4,MICU3,KCNT2,ZNF74,LYPD6,TMEM237,DPYSL5,ZNF225,NAV3,EPM2A,AMN1" MicroRNA hsa-miR-3127:mirSVR_highEffct hsa-miR-3127:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.48E-59 1.40E-55 8.95E-59 8.25E-58 164 732 "CLK4,METAP1D,ADRA1D,LRFN2,SNX32,AGT,RTL9,OSBPL1A,GPRASP2,CNTNAP1,DGKZ,ALS2,LGR5,CDC14B,PDXK,IGDCC4,ATM,ATP2B1,ALDH7A1,BCL2L2,NAE1,CACNA1B,CACNA1E,CACNB4,KALRN,TRIM41,RUNX1T1,NFS1,CHI3L2,RAB33A,CP,CRYM,SNCAIP,SEC24C,CSF3R,SUSD5,NCAN,RIMS2,GPRASP1,DBI,LYPD1,ZC3H11A,SV2A,ECM2,DNM1L,PHC2,EIF4G2,PLEKHA1,PCOLCE2,PAN3,ERBB2,CLVS1,FAM198B,WAC,TOMM40L,TESK2,GORAB,FER,UBE2E3,CAP2,ANKFY1,NOP56,PDLIM5,TPK1,CELF1,CGREF1,PHYHIPL,MEGF11,GABRG2,C15orf41,GCNT2,BRD8,ZNF638,GOLGB1,GPD2,PRLHR,RAPGEF4,GRM2,CIT,KIF3A,RNF165,LINC01551,IL6ST,IL11RA,OLFM3,KCNC2,KCNMA1,KIT,NCOA7,MAT2A,TM6SF1,MSI1,MSR1,MTTP,MYO7A,NAP1L2,NINJ2,NNAT,PDCD2,PDE4D,GNG2,NLE1,PRRX1,EPB41L4B,PPP2R5E,PKN2,CNNM2,PLPPR1,ZSCAN32,ZIK1,ACSM5,ZSCAN2,MARCH1,NWD1,MSANTD2,ERI2,RFX2,RGS3,RGS12,RLBP1,SLC25A36,GSTCD,ACER3,RXRG,AMER2,TNFRSF19,COPZ1,KIF21A,ASAP3,SHMT2,RUFY2,SLN,ABTB1,RCOR3,INAVA,LIMCH1,CABCOCO1,USP33,WDTC1,FNBP1,TAB2,GANAB,SYN1,TACC1,DDHD2,FAM208A,ADGRL3,ZEB1,AKNA,RNF216P1,SIRT1,SLC44A1,HEY1,HEY2,LRRC8A,RIMBP2,NPL,SYNPO2,RFTN2,ZNF154,LINC02210,FAM13C,FBXO36,CPNE4" MicroRNA hsa-miR-4280:mirSVR_highEffct hsa-miR-4280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-59 1.63E-55 1.05E-58 9.64E-58 148 601 "TTYH1,KCNH8,DPY19L2P4,CC2D2A,C1QTNF3,ALCAM,MAP4K3,SUGT1P4-STRA6LP-CCDC180,BCAS1,APP,ARNTL,ASPH,ASTN1,ALDH4A1,ATP2A2,BACH1,ADGRB3,ARHGEF7,C5,CACNB2,SPAG9,PLEKHB1,LSMEM2,EPS15L1,CLCN3,SRP14-AS1,AKAP7,FAM149A,AKAP6,SLC25A27,SEC31B,FEZ2,CSNK1G3,DZIP3,UBXN2A,PNPLA8,RIMS2,GPRASP1,TOMM20,PITPNC1,JAKMIP2,USP3,DPH1,DRD1,DTNA,WDPCP,FRY,KMT5B,ARMCX1,SH3YL1,SCML2,ATP8A1,GTF2IRD2,POLR1B,FLT1,ANKFY1,SLC37A3,GABBR1,AHCYL1,DNER,OS9,GNAS,ADGRA3,ATF7,GRIA1,PTPN5,HMGCL,NEGR1,LINC00667,LRRTM3,ITPKB,KCNA4,KCNN2,IPO5,PAXBP1,SYT9,LRP1B,MEIS1,SRSF12,MOBP,MOG,BLOC1S2,NELL1,NEK1,NF1,CNOT4,PDE4D,PDGFRA,OLA1,LRP12,NXPH1,PRKACB,GRAMD1C,WBP1L,QRICH1,CNTLN,MTMR10,STK32A,EML5,PTPRG,RAP1GDS1,DBX2,NUDT11,RNASEL,CCDC82,RPE,RPE65,TCP11L1,FAM161B,AMER2,LRRTM4,COPZ1,SCAF8,ST3GAL3,CCDC88A,SMARCE1,MYO16,HECW1,KDM4C,RAP1GAP2,STAU1,NUDT10,COBL,ADGRL3,VWC2,TCF12,WDR7,SIK3,SIRT1,AP4E1,ARL10,MTMR14,NR2E1,PPIL6,ZKSCAN5,HIRA,FAM155A,GORASP1,FLRT2,BEST1,SLC26A10,MKRN3,ANKS1B,HPS4,MVB12B,DOCK8,ZNF248,JPH3" MicroRNA hsa-miR-485-5p:mirSVR_highEffct hsa-miR-485-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.02E-59 1.69E-55 1.09E-58 1.00E-57 178 855 "SYN3,NBAT1,NDRG3,RTL9,WDR35,TAOK1,LRRC7,BCAR3,AMPD2,OGT,PDE8B,ASPH,NUMB,ATP2B2,RNF182,DPY19L3,DST,BTK,BAIAP3,CACNB2,USP2,RGN,ARHGEF1,AP4M1,LRBA,LGI1,TIGD7,CHN2,RAB33A,ARMC8,SUMF2,MFSD4A,CHD1L,PNKD,NCOR1,TRIM69,SEC24C,FEZ1,MICAL2,PDE4DIP,EARS2,RUSC2,NTM,SLC29A4,DTNA,FAM135B,PHC2,RASGRP1,IRAK4,EPB41L2,FABP7,ACSL4,EFEMP1,STRADA,FDFT1,PRMT5,SEC24B,NBEA,KHDRBS3,CELF1,OGA,DENND2A,GALC,RAPGEF6,GGT7,PPARGC1A,GLDC,GLI2,GNAL,ZNF782,TDRKH,GPR34,GRIK3,TLX1,OPALIN,ICA1,IL11RA,KCNK2,CREG2,SYT9,LDLRAD3,MEIS1,CD200,MSRA,CTNNA3,MYO7A,MYT1,P2RY13,NFE2L2,NOVA1,GPR88,OPA1,PDGFRA,SERPINE2,PMP22,PRRX1,MBOAT7,FSD1,MED1,PRKACB,PRKCG,SAMD9,BCAS3,CNTLN,PLPPR1,SPDL1,PTPRE,PEX5,ZSCAN2,RDX,SLC6A15,DPF2,ARHGEF10L,RIC8B,RPRD1A,ZFHX4,RAVER2,SPIN3,ABCA11P,FAM192A,LRRTM4,ASIC4,SHC4,CHD9,ST3GAL3,PPP4R3A,KBTBD4,ELMO2,ATF7IP,ZFP1,MAST1,RCOR3,INAVA,SNCA,KIF13A,CABCOCO1,ANKFN1,SOX5,ZSWIM8,KDM4C,SPART,SYPL1,MTCL1,FBXW11,ANO4,TPCN2,TMEM151B,HIF3A,SIK3,CRB1,TIE1,FAM124A,KAT6B,WBP2,ZNF384,ZNF346,UGT8,PLPPR2,CCDC136,RICTOR,SF1,ZNF17,ZNF540,ATP6V0E2,PLPP4,GPR158-AS1,SLC26A10,CADM2,LINC02210,URM1,WNK3,NELFE,PLSCR4,PARP11,EPM2A,PHTF2,SLC4A10,FAM198A" MicroRNA hsa-let-7f:mirSVR_highEffct hsa-let-7f:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.41E-59 1.91E-55 1.23E-58 1.13E-57 175 829 "NBAT1,KLHL32,BRAP,ERMN,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,DACT3,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,CH25H,AIFM1,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,SLC25A27,AHCTF1,IGDCC3,MFSD4A,MICAL2,OSBPL3,PDE4DIP,BOC,FRMPD4,DAPK1,B3GAT3,KLHL3,DLG2,DMD,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,RACK1,GORAB,FGF11,FGR,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,CAB39,GAD1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,BRD8,POLL,FUT10,CNTRL,ADAMTS8,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,LRRC25,NKD1,IGSF1,DIPK1A,NME9,KCNC2,KCNJ3,KCNJ11,KCNK1,MDM4,MEIS2,MOBP,SESN3,RSPO2,NAP1L1,FXYD6,CNOT4,NOVA1,HCN1,OGG1,SNTG1,SERPINE2,FAM218A,XRN1,PMP2,PRRX1,SPATA6,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,MIR124-2HG,ATXN7,FAM19A1,FNIP1,KIF27,FNDC3A,BDP1,HECW1,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,ACSL6,TCF12,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,VSNL1,RICTOR,LYPD6,ZSCAN26,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-636:mirSVR_highEffct hsa-miR-636:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.66E-59 2.05E-55 1.32E-58 1.21E-57 150 618 "SYS1,ACTN1,ADARB2,ADD2,BRAP,AGT,RTL9,NME5,OSBPL8,SEMA6A,MARCH4,AMPD3,ANK1,SHTN1,NUMB,N4BP2L1,DPY19L3,TTLL9,ADGRB3,LINC00847,DST,NAE1,VSTM2A,ZNF501,KRIT1,AIFM1,LGI1,JAM2,CLCN4,IFFO1,CRHBP,HAPLN1,SOCS5,VAC14-AS1,PUM1,DCAF4,USP6NL,GAPVD1,ARHGAP24,HP1BP3,SV2B,RABGAP1L,DLX1,HS3ST2,NR1D2,DNAJB6,ATL1,KLHL5,SUGP2,EGFR,MBNL2,IRAK4,EMX2,RTN3,NRN1,FAM198B,FCGR3A,KAT8,GTF2IRD2,FGF12,SEMA4D,NELFCD,WDR83,DACH2,CGREF1,OGA,GABRB1,IP6K3,SIGLEC8,MTHFD2,GGTA1P,KIRREL3,TXNL4A,FERMT2,GPD2,GPR34,GRIK2,RNF165,FAM222A,HPS5,ATXN2L,RBPJ,BRINP3,LRRTM3,KCNH1,KCNMA1,HECTD2,PPM1L,PCBP3,TBC1D25,OCRL,PCDH9,ZDHHC8,DUSP26,GDAP1L1,LRP12,PRKACB,PKN2,MASP1,RELN,QRICH1,TMEM260,STK32A,ZSCAN32,OCIAD1,RFX4,AMER2,DHX30,LRRC55,SORCS3,RIMS1,SOX5,BEX1,DIP2A,NECAB1,SYNE2,C12orf76,TBX15,TCF4,SATB2,ZFP90,SZT2,DOCK9,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,SIK3,C18orf54,HEY2,TNS1,TPD52,PRMT8,SMUG1,TRO,FNDC5,TTC3,RPL7L1,RICTOR,TRIM9,SYNC,CA10,PRTFDC1,ITM2C,SMIM8,MSRB3" MicroRNA hsa-miR-1197:mirSVR_highEffct hsa-miR-1197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.67E-59 2.06E-55 1.32E-58 1.21E-57 166 751 "FAM43B,ADCY6,ADD3,GPR158,CC2D2A,AK2,PCDH10,FAM135A,BIN1,PKP4,ALS2,MADD,ATM,ATP1B3,DPY19L3,CFLAR,RAB29,CA4,CACNA2D1,CACNB2,PRC1,ZNF501,CBFA2T2,CD38,CDC25B,DCLK1,TIGD7,NDST3,TPP1,QKI,LY86,SLC4A8,HS3ST5,CREM,FEZ2,SOCS5,PPP6R2,CCDC144A,TBC1D5,TMEM170A,PABPC5,ARMCX4,C8orf34,CEP170,BLOC1S6,ZC3H11A,DDX46,HS3ST2,DNAJB6,FARSB,ANKRD46,EIF5,TENM1,RGS17,VPS13B,DNAJC27,ADGRV1,FABP7,TMEM132C,TUBA1B,TMEM164,PRKAG2,FHL1,UFM1,CELF1,NSG1,PHYHIPL,GABRG2,CAB39,TUBA8,SULT1C4,GDF9,ADAM28,PPARGC1A,TNRC6A,ZNF638,GNAL,CECR2,PCLO,FAM19A2,PTPN5,RABL2A,FRMD3,HNF4G,HTR5A,USP54,TUBB2B,JAK2,KCNK1,LAMP2,PAXBP1,VWA5A,MAT2A,MEIS2,DDX25,NTRK3,P2RX7,PCMT1,PDYN,FAM216A,SLC25A23,HMGCLL1,PNMA3,SH3KBP1,HYDIN,GON4L,TMEM260,PTPRO,PTPRZ1,SUSD4,TRIM68,GTDC1,SLC25A36,CARF,PNMA8A,ELP2,KIAA0895L,LRRK2,SAFB,SCN2A,KIF21A,NUBPL,CLSTN1,SLA,CCDC88A,SORCS3,RIMS1,SNAP25,KDM4B,USP33,PDZD2,TNIK,SP4,KDM4C,ZC3H13,CDK19,NPAS3,NKAIN2,RGL1,PLCB1,TAC3,DNMBP,ZEB1,SZT2,ARL10,ASXL3,TMPO,DAAM2,KAT6B,CDK20,AMACR,TSC1,TUBB2A,UGT8,FAM181B,BCL2L13,MTCH1,FTSJ1,CA10,ADAMTS9,SCG2,CIAPIN1,UBE3B,PIANP,NETO1,SENP7" MicroRNA hsa-miR-26a:PITA hsa-miR-26a:PITA_TOP PITA 4.89E-59 2.75E-55 1.75E-58 1.62E-57 131 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SHTN1,ATP1A2,SLC4A4,NOL4,FUBP1,CACNB4,CALM1,MAP7,SRSF11,FOXN3,SOCS6,CHN2,KMT2C,DNAJB5,TMEM184B,CNR1,AKAP7,SLC4A7,ACBD5,SOCS5,ERC2,PLCXD3,CTNND2,ST18,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,G3BP2,DLG4,DMD,USP3,ST8SIA3,RBM12,EIF4G2,EIF5,ELAVL2,PAN3,FKTN,CAMSAP1,MEX3B,NEK6,SRCAP,TNRC6A,GRB10,GRIA4,ADAMTS6,KLF12,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,CD200,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PDGFRA,PFKFB3,FAM98B,GPSM2,PLCL1,PLP1,PCDH18,FA2H,PPP2R5C,PPP3CB,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,SLC6A15,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,SFPQ,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,ZCCHC24,CLASP2,EPB41L3,LARP4,STAC2,VAMP1,PLCB1,FAM208A,PSD3,AMACR,TRPC3,AMOT,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK1,WNK3,SLC17A6,PHTF2,VANGL2" MicroRNA hsa-miR-26b:PITA hsa-miR-26b:PITA_TOP PITA 4.89E-59 2.75E-55 1.75E-58 1.62E-57 131 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SHTN1,ATP1A2,SLC4A4,NOL4,FUBP1,CACNB4,CALM1,MAP7,SRSF11,FOXN3,SOCS6,CHN2,KMT2C,DNAJB5,TMEM184B,CNR1,AKAP7,SLC4A7,ACBD5,SOCS5,ERC2,PLCXD3,CTNND2,ST18,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,G3BP2,DLG4,DMD,USP3,ST8SIA3,RBM12,EIF4G2,EIF5,ELAVL2,PAN3,FKTN,CAMSAP1,MEX3B,NEK6,SRCAP,TNRC6A,GRB10,GRIA4,ADAMTS6,KLF12,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,CD200,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PDGFRA,PFKFB3,FAM98B,GPSM2,PLCL1,PLP1,PCDH18,FA2H,PPP2R5C,PPP3CB,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,SLC6A15,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,SFPQ,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,ZCCHC24,CLASP2,EPB41L3,LARP4,STAC2,VAMP1,PLCB1,FAM208A,PSD3,AMACR,TRPC3,AMOT,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK1,WNK3,SLC17A6,PHTF2,VANGL2" MicroRNA hsa-miR-1297:PITA hsa-miR-1297:PITA_TOP PITA 4.89E-59 2.75E-55 1.75E-58 1.62E-57 131 473 "PLEKHH1,SLC24A4,ZNF608,INTS2,AMPH,LRCH2,EP400,SHTN1,ATP1A2,SLC4A4,NOL4,FUBP1,CACNB4,CALM1,MAP7,SRSF11,FOXN3,SOCS6,CHN2,KMT2C,DNAJB5,TMEM184B,CNR1,AKAP7,SLC4A7,ACBD5,SOCS5,ERC2,PLCXD3,CTNND2,ST18,DOCK4,HDAC4,SPOCK2,PITPNC1,JAKMIP2,MFAP3L,C2CD2L,SACS,G3BP2,DLG4,DMD,USP3,ST8SIA3,RBM12,EIF4G2,EIF5,ELAVL2,PAN3,FKTN,CAMSAP1,MEX3B,NEK6,SRCAP,TNRC6A,GRB10,GRIA4,ADAMTS6,KLF12,MIER3,IGF1,ZIC5,SMAD1,MAP2,MARK1,MAT2A,CHIC1,MITF,CD200,BLOC1S2,MXI1,NEXMIF,NEK1,PCDH9,PDE4B,PDGFRA,PFKFB3,FAM98B,GPSM2,PLCL1,PLP1,PCDH18,FA2H,PPP2R5C,PPP3CB,RANBP3L,CEP41,VPS13C,PTPN13,PTPRD,TTC13,SLC6A15,RGS4,SLC25A36,NUDT11,ZFHX4,CARF,RTN1,SALL1,SEMA6D,FNIP1,SFPQ,MRAS,FBXO11,NLGN1,PPP4R3A,SLC12A2,TET1,TMCC1,FAM126B,ZCCHC24,CLASP2,EPB41L3,LARP4,STAC2,VAMP1,PLCB1,FAM208A,PSD3,AMACR,TRPC3,AMOT,TBC1D15,CLDND1,MKRN3,ZBTB38,WNK1,WNK3,SLC17A6,PHTF2,VANGL2" MicroRNA hsa-miR-588:mirSVR_highEffct hsa-miR-588:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.31E-59 3.55E-55 2.26E-58 2.09E-57 158 686 "KCNH8,CSMD2,KLHL32,PWWP2A,PTCHD1,HACE1,ALCAM,ABCD2,ARHGAP20,ANK3,FGD2,MAP4K3,ALS2,PHYHD1,SHTN1,IGDCC4,RGS20,DDX3Y,ATP2B1,ZNF582,BACH1,ADGRB3,RGS9,DST,BTK,CA12,TRIM41,TMEM257,CASC2,SYNPR,TJP2,COL4A5,ABI3BP,COX4I1,TRIM69,CCDC144A,CYBB,RIPOR2,LONRF1,DGKG,COPS7A,ZC3H11A,RHOBTB1,AASDH,FAM135B,EDNRA,EDNRB,FCF1,OPTN,EFNB3,FAM13A,PLEKHA1,TMEM35A,DCTN4,EMX2,EPHA5,ZNF549,RCSD1,ABCA8,RACK1,FCGR1B,GORAB,FHL1,OGA,FYN,GABRB1,GALNT15,GAD1,ARPP21,DISC1,TUBGCP4,GHR,DCLK2,GPM6A,TDRKH,NR3C1,ZNF496,CLASRP,FAM107A,ADAMTS6,MAEL,CFAP126,ZNF546,DOCK7,JAK1,KCND2,LMO2,MAP2,MARK1,LDLRAD3,MRPL42,CCDC80,RTL5,DNHD1,CLEC9A,SLC11A2,P2RX7,GPR137C,PAK3,PCDH9,PDE3B,PDGFRA,PDYN,NALCN,TMIE,NLE1,PLIN1,HMGCLL1,ING3,PTPA,PKN2,APTX,TMEM260,PTPRO,ACSM5,SEC61A2,CCDC82,ROBO1,FBXW7,SEMA6D,SCN7A,CCDC92,SEPHS1,SLC12A2,ELMO2,MYH15,SMARCE1,RIMS1,SOX5,SPATA7,MYCBP2,IQSEC2,CLSTN2,POGZ,SULF2,KLHL7,SLC37A2,TACR1,DMXL2,TEX15,TF,SLC44A1,ERCC6L2,DAAM2,TNR,ZNF384,RUNDC3B,TRO,UBE2H,GUSBP1,ZFP37,ZIC3,ZNF24,MDH1B,SLC17A7,KCNAB1,PAK5,NETO1" MicroRNA "AATGTGA,MIR-23A:MSigDB" "AATGTGA,MIR-23A:MSigDB" MSigDB 6.76E-59 3.80E-55 2.42E-58 2.23E-57 120 396 "MTUS1,PCDH19,OSBPL8,ARHGAP20,PKP4,PPP4R4,TMEM263,NCOA1,SLC4A4,B3GALT2,CDK5R1,SYNJ1,FOXK1,RUNX1T1,CCK,CCNH,CBFA2T2,MAGI1,DLGAP2,SOCS6,NRXN3,CLCN3,NRXN1,QKI,MAP4K4,COL4A5,COL11A2,AKAP12,LRIG1,CSNK1G3,PLCXD3,ST18,TOX,PHF19,MAML1,DNAJC6,POM121,SRGAP3,G3BP2,WDR20,DLG2,DLX1,CPEB2,EGR3,TNK2,ETV1,EYA1,PTK2B,SPSB4,SUCO,CAB39,NEK6,ARFIP1,PPARGC1A,GLYR1,GLS,TNRC6A,ADAMTS6,HAS2,HNF4G,IL6R,KCNK3,IPO5,PAXBP1,MAT2A,MDFI,MEF2C,MEIS1,MEIS2,KITLG,AFF1,MSI1,NAP1L1,NRGN,PRTG,PDE4B,ZNF655,ING3,PPP2R5E,PKIA,ANKHD1,ROBO2,SNX22,LGR4,SEMA6D,SATB1,ATXN1,ZFP2,SEC14L1,SGK1,AMBRA1,FBXO11,SHANK2,BTBD7,CPEB4,PALLD,SOX11,ZNF423,NKAIN2,LRRC4,SEPT3,CAMTA1,ANO4,ATMIN,SATB2,PUM2,TGFBR3,NACC2,TMOD1,TMPO,TPM3,WBP2,TBC1D15,VSNL1,NSD2,ZIC1,MICU3,PRDM10,SNX27,WNK3" MicroRNA "AATGTGA,MIR-23B:MSigDB" "AATGTGA,MIR-23B:MSigDB" MSigDB 6.76E-59 3.80E-55 2.42E-58 2.23E-57 120 396 "MTUS1,PCDH19,OSBPL8,ARHGAP20,PKP4,PPP4R4,TMEM263,NCOA1,SLC4A4,B3GALT2,CDK5R1,SYNJ1,FOXK1,RUNX1T1,CCK,CCNH,CBFA2T2,MAGI1,DLGAP2,SOCS6,NRXN3,CLCN3,NRXN1,QKI,MAP4K4,COL4A5,COL11A2,AKAP12,LRIG1,CSNK1G3,PLCXD3,ST18,TOX,PHF19,MAML1,DNAJC6,POM121,SRGAP3,G3BP2,WDR20,DLG2,DLX1,CPEB2,EGR3,TNK2,ETV1,EYA1,PTK2B,SPSB4,SUCO,CAB39,NEK6,ARFIP1,PPARGC1A,GLYR1,GLS,TNRC6A,ADAMTS6,HAS2,HNF4G,IL6R,KCNK3,IPO5,PAXBP1,MAT2A,MDFI,MEF2C,MEIS1,MEIS2,KITLG,AFF1,MSI1,NAP1L1,NRGN,PRTG,PDE4B,ZNF655,ING3,PPP2R5E,PKIA,ANKHD1,ROBO2,SNX22,LGR4,SEMA6D,SATB1,ATXN1,ZFP2,SEC14L1,SGK1,AMBRA1,FBXO11,SHANK2,BTBD7,CPEB4,PALLD,SOX11,ZNF423,NKAIN2,LRRC4,SEPT3,CAMTA1,ANO4,ATMIN,SATB2,PUM2,TGFBR3,NACC2,TMOD1,TMPO,TPM3,WBP2,TBC1D15,VSNL1,NSD2,ZIC1,MICU3,PRDM10,SNX27,WNK3" MicroRNA hsa-miR-632:mirSVR_highEffct hsa-miR-632:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.52E-59 4.23E-55 2.69E-58 2.48E-57 161 712 "SERPINA3,ARID1A,XKR4,SORCS1,PTCHD1,BEND6,INTS2,ANK2,USP28,PHF12,AMER3,LRRC4C,ATP2A2,DPY19L3,ADGRB3,RGS9,SGCE,SPAG9,NFS1,ZBED1,MAGI1,TIGD7,KMT2C,PPT2,SLC4A8,HAPLN1,ABCG1,SNCAIP,SEC24C,CSNK1G3,SIPA1L1,VCAN,FAM169A,SLITRK5,CTNND2,RIMS2,MATR3,DDX46,NTM,EXOG,DYRK1A,E2F5,CERCAM,DCTN4,EPB41L1,DENND4A,RASL12,REEP2,FAM198B,TUBB3,EFEMP1,CEP78,GORAB,FER,SUCO,FOXF2,FLT1,ANKFY1,NELFCD,SORBS1,ZNF605,NSG1,STAG2,GABRA2,C15orf41,GFRA2,PPARGC1A,RAB30,MSL3,ZNF638,GNAO1,FUT10,RAPGEF1,PTPN5,PSIP1,GYG1,NEGR1,HSP90AA1,SMAP1,IDH3B,IGF1,SCIN,KCND2,MBNL1,SYT9,LRP1B,MEF2C,MMP16,ERICH3,MYO7A,PABPC1L2A,RCOR2,NRCAM,NTRK2,NUCB2,GNG2,PKD1,SNX10,JAKMIP1,PMP22,ING3,SEPT4,NXPH1,POLR2F,RAB39A,MAPK10,GRAMD1C,MASP1,SNRK,MDGA2,CNTLN,PTPN13,OCIAD1,PTPRE,TTC13,FAM66C,RASGRF2,RDX,SLC6A15,RFX4,RPRD1A,CARF,KIAA0895L,ABCA11P,ATXN2,LRRTM4,CASC3,NLGN4Y,FNDC3A,FAM81A,SLC6A8,BTBD7,CPEB4,SORCS3,RCOR3,PDZD2,TSNAXIP1,SP4,ZC3H13,LHPP,SEPT8,SYP,C12orf76,DNMBP,FBXW11,GPRIN3,FAM200B,AKTIP,HEY2,RFTN2,UBE2H,OSBP2,TRIM9,ZNF45,SLC26A10,LYPD6,EML6,ZSCAN26,CA10,TIGD6,SLC4A10" MicroRNA hsa-miR-424*:mirSVR_highEffct hsa-miR-424*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.88E-59 4.99E-55 3.17E-58 2.92E-57 151 630 "KCNH8,ACADM,CCDC85A,GALNT13,USP31,DPY19L2P4,OSBPL6,ABCD2,GPAM,FAM131A,CASK,CAPRIN2,SLC4A4,DPY19L3,IL33,CALM1,VSTM2A,TMEM257,CDH8,NUMBL,CHN2,ZBED5,NRXN1,FHL5,CNTNAP2,CFAP61,PUM1,USP6NL,ARHGAP32,C8orf34,ZEB2,HP1BP3,GSDME,POM121,SMG7,DRD1,ANKRD46,SYT15,KLHL5,YAF2,CELSR3,FAM13A,KMT5B,KCTD3,PAN3,STX2,SRRM1,IGSF6,DNAJC27,TUBB3,GORAB,MED12L,OLFM1,SUCO,MEX3B,FOXG1,CAP2,FOXF2,RGPD5,SMC2,CAMKK2,CELF1,CSPG5,DLL3,STAU2,GABRA5,GALR1,NEK6,SIGLEC8,LRRC37A6P,TXNL4A,RAB30,GLS,GNAS,GPT2,GPR37,GYG1,WIF1,MAEL,HNRNPK,HECTD2,MAOB,MARK1,MAT2A,SRSF12,KITLG,ZNF680,MSR1,NDP,NFIX,PDGFRA,PNMA3,EXOSC10,PPM1B,CEP41,MASP1,MDGA2,PTX3,NUDT11,RNASEL,FBXW7,PTGR2,WLS,SEMA6D,CSRNP3,ASRGL1,ST6GAL1,SLC20A2,SMARCE1,CABCOCO1,SPART,C11orf87,TROVE2,STOX1,SSTR1,LARP4,NXT2,ELOVL4,KANK1,PLCB1,SYT1,PJA1,KLHL4,CUX2,PCDHGA11,FRYL,THBS4,THRA,LRRC8A,FAM124A,TRIO,ZMYND8,SSBP2,UGT8,PLEKHH2,CCDC14,XRCC4,ZBTB14,ZNF17,ZSCAN26,EMSY,MFF,PRDM2,TRIM16L,PCBP4,GOPC,UBE3B,HNRNPA3,ADAMTSL3,KLHDC1,CPNE4" MicroRNA hsa-miR-675*:mirSVR_highEffct hsa-miR-675*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.56E-59 5.37E-55 3.42E-58 3.15E-57 141 551 "CSMD3,ADAR,KLHL32,GALNT13,KIAA1211,PTCHD1,BEND6,OSBPL1A,PCDH10,FAM135A,CDC42BPA,CCDC146,USP28,PKP4,APC,SHTN1,CDK13,ASPA,ASPH,ZBTB10,INSYN2B,ATP2B1,N4BP2L1,BID,DST,SYNJ1,SYNJ2,WASF1,PTBP2,MAGI1,CLGN,CHN2,SYNPR,RAB33A,C4orf33,ZFP28,CP,SEC24C,ATRNL1,VCAN,ST18,SCRN1,GSDME,DDX46,DMTF1,PDCD6IP,DYRK1A,ABCC9,WDPCP,HIPK3,YAF2,C3orf18,ENPP6,TOMM40L,SLC9B2,SUCO,CAP2,FOXO3,ATP2C1,CSPG5,SYT17,DBF4,DIPK1C,ATP2B1-AS1,GSTT2,PLD5,IL6ST,JAK2,KCNA4,CREG2,VWA5A,NCOA7,LYPLAL1,MBP,MDM4,MEIS1,SRSF12,MITF,CD200,BLOC1S2,ADAM22,NAP1L3,NDUFA5,NEUROD2,NRCAM,PAK3,DPY19L2P2,PDCD2,PLCL1,PLP1,EPB41L4B,NXPH1,PPM1B,DIRAS2,VPS13C,PTPRO,ARID4A,DBX2,ZDHHC14,SLC6A15,ZYG11B,RGS4,ELP2,NEK11,RPL15,SCP2,TNFRSF19,SH3GL3,PPP4R3A,SPHKAP,TET1,CPEB4,ZFP1,SMARCE1,RCOR3,MBD5,BDP1,KDM4C,LMO3,ELOVL4,AJAP1,SYNE2,ATMIN,ZEB1,TCF12,RALYL,DICER1-AS1,AP4E1,SLC44A1,NR2E1,ERCC6L2,TMEFF2,UBE2H,ZIC2,ZNF711,MICU3,TRIM9,PLPP4,UPF3A,LINC00632,SLC17A6" MicroRNA hsa-miR-1299:PITA hsa-miR-1299:PITA_TOP PITA 9.65E-59 5.42E-55 3.45E-58 3.17E-57 122 411 "GPR158,PCDH19,SEMA6A,SPOP,NCOA1,ATP1B3,ATP2B1,RNF182,ADAM23,CACNA1I,BTRC,CA8,CACNA1E,MAP7,DLGAP2,NUMBL,SYNPR,CLCN3,NRXN2,SLC4A7,MYRIP,IGDCC3,CTNND1,PUM1,BOC,PHF19,CEP170,RHOBTB1,SRGAP3,G3BP2,DLG4,YAF2,MBNL2,TENM1,TNK2,EPB41L2,RASGRP2,ANKRD13B,ERBB4,NCALD,DLC1,TOMM40L,MED12L,AGAP2,SEMA4D,HRASLS5,GATM,MSTN,TCERG1,LUZP2,GPD2,ATF7,GRB10,PSIP1,ADAMTS6,BACH2,MIER3,NKD1,SLC6A17,LRRTM3,KCND2,MARK1,SYT9,MEIS2,NEUROD1,GPR88,CHAMP1,PDE3A,KCTD15,SDK2,PACSIN1,POU3F2,RANBP3L,CEP41,GDPD1,FAM120C,OXR1,GTDC1,RPS6KA2,HUNK,KCNIP1,RYR3,CSRNP3,SOX6,SH3BGR,CHD9,FAM214B,LMBRD1,MYT1L,FNBP1,ITPRID2,ERBIN,STAU1,ZSCAN29,ZC3H4,PRRC2C,SYN2,ANKRD28,MCF2L,TBX15,TCF4,CUX2,RALYL,FRYL,DICER1,ZFPM2,CHST8,HHIP,FBXL16,TIAM1,RBFOX2,ZIC1,NDRG4,SMARCAD1,SLC30A4,CADM2,CSDE1,NAV3,SNX27,HNRNPA3,MSRB3,FXR1" MicroRNA hsa-miR-221*:mirSVR_highEffct hsa-miR-221*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-58 6.20E-55 3.94E-58 3.63E-57 156 672 "SYS1,GALNT16,SORCS1,KIAA1324,LRRC7,EP400,MYH7B,PARG,ASPH,TTLL9,ADGRB3,CDK5R1,SCAPER,CACNA1E,CALB1,KALRN,PTBP2,NFS1,METTL6,RGN,CNGA3,CNR1,SMARCAL1,GDA,ABCG1,SNCAIP,CSNK1G3,NCAN,SOCS5,ERC2,CCDC144A,RIPOR2,DAPK1,GIT2,DBN1,COPS7A,MAGI2,ARNT2,ECM2,DNAJB6,DNM1L,HIPK3,EGR3,C3orf18,DMTN,EPHB1,SRRM1,CEP85L,TOMM40L,ZSCAN30,PPP1R1B,FGF12,MEX3B,PSD2,TRIM16,ATP2C1,DACH2,STAU2,ERAP1,ALDH1L1,FREM1,PCDH17,TNRC6A,HTATSF1,PCLO,GRIK2,GRM7,TMEM25,RASSF8,UBE2QL1,ARHGAP36,HMGB1,HMGCR,AGBL5,TCEAL6,SMAP1,IRF8,ZNF678,JAK2,KCNK2,MBNL1,MEIS1,POC1B,ZNF680,BCO1,PABPC1L2A,NCAM1,NEFH,NF1,NFE2L2,OGG1,CYTL1,HERC2P3,FAM218A,PPP2R5C,RASGEF1B,MAPK10,GRAMD1C,SPDL1,TMEM260,PTPRG,OXR1,ARID4A,SLC6A15,GTDC1,RFX4,ZDHHC4,RGS3,RGS4,KLHDC8A,ROBO1,NEK11,EMID1,DGLUCY,ATXN7,HOGA1,LINC00461,TRIM46,KIF21A,ITSN1,CNKSR2,SLC6A1,BTBD7,SNRPN,UNC80,SOX3,IDI2-AS1,SPART,SS18,NUDT10,IQCE,FBXW11,SATB2,TMEM151B,AKTIP,GZF1,ANKRD24,PRMT8,SMUG1,RUNDC3B,TSC1,TTC3,PLEKHH2,BCL2L13,ZNF708,ZNF138,ANKS1B,PCBP1-AS1,ADAMTS9,CIAPIN1,TRIM16L,WNK3,RGS7BP,UBE3B,PHTF2,FBXO36" MicroRNA hsa-miR-122:mirSVR_highEffct hsa-miR-122:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.16E-58 6.52E-55 4.14E-58 3.82E-57 148 607 "ACTN1,KLHL32,GALNT13,AMPH,UPRT,INSYN2B,ATP2B1,NOL4,DPY19L3,ADGRB2,CFLAR,C5,CANX,HIP1R,CBR1,C1orf52,LGI1,NUMBL,PLEKHB1,TJP2,SEC31B,CRMP1,CLIP3,CS,CTNND2,DOCK4,HDAC9,IST1,SPOCK2,CNIH3,DMD,DTNB,DYRK1A,ABCC5,FAM13A,PHF20L1,TENM1,RCSD1,SIRPB1,F8,CLVS1,RPS6KC1,GTF2IRD2,CAP2,NOP56,ARFGAP2,GABBR1,GABRA3,GABRA5,GAD1,FAM120B,GALC,SYT17,IGSF5,MMADHC,TNRC6A,MSL3,LUZP2,DCLK2,GPD2,GPM6B,TUBA1C,GRIA2,IL6ST,DIPK1A,KCNJ16,KCNK2,SYT9,MDM4,MEIS2,ERICH3,MYCN,MYO9A,NDUFA5,NEK1,LRIT2,SLC11A2,NTRK2,OCRL,GPR137C,ZNF827,PAK3,PCSK2,PDCD2,GPR173,ZDHHC8,GDAP1L1,CCSER2,PKM,MASP1,CNNM2,PTHLH,PTPRB,RASGRF2,RGR,TMLHE,RAVER2,CYB561D1,CCDC102B,RXRG,AP1AR,TNFRSF19,SUPT20H,ITSN1,SH3GL2,FNDC3A,FHOD3,SLITRK3,BCAN,ZNF365,SLC4A3,SLC6A11,SMARCC2,LIMCH1,RIMS1,ZNF415,UNC80,NPAS3,SSTR1,SS18,NCDN,INKA2,STAU1,RGL1,KANK1,NUDT10,UNC5D,WDR7,SIRT1,HHIP,TLR4,PRRT1,SYNPO2,SMUG1,STXBP4,UGT8,DNAJC12,OSBP2,MICU3,LYPD6,SMARCAD1,MAP3K12,PRTFDC1,SLC17A7,PHTF2,JMJD1C,KLHDC1,CPNE4" MicroRNA hsa-miR-220a:mirSVR_lowEffct hsa-miR-220a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-58 1.03E-54 6.56E-58 6.05E-57 147 601 "ACTN2,ARID1A,GPRIN1,SMIM17,DPP10,MAP4K3,KCNAB2,AMER3,APP,MADD,ARRB1,PCDHGB4,EIF4G3,SLC2A11,N4BP2L1,ADAM23,DST,MTMR2,JAZF1,CALM1,RHBDL1,ZNF501,LDB2,CDH10,CHRM1,LHX2,RAB33A,CLCN4,STOML1,CLTB,TJP2,LETMD1,RBM39,SLC32A1,ANKRD44,GDA,SLITRK5,PHF14,RUBCN,MYADM,FGFR1OP2,KATNAL2,LONRF1,GIT2,HP1BP3,KLHL3,RHOBTB1,DYRK1A,APH1A,EIF4G2,DENND4A,SPEG,RRAGB,ARMCX1,DLC1,FCGRT,POLK,SUCO,CAP2,WDR83,POMT1,TMEM107,CHL1,GAD2,GAP43,C15orf41,DISC1,GATM,SPIN1,DCLK2,GPT2,MCHR1,SOX21,PADI2,TNFAIP8L3,SMAP1,ZNF546,KCNJ5,MAOB,MARK3,MYO7A,RTL5,PABPC1L2A,NPTX2,PAK3,PCDHGC3,PCDH9,PCMT1,GPR85,PFKFB3,ING3,POLG,PPARA,PCDHB17P,PPP2R5C,PRKACB,PTPRB,ZFHX4,RPS20,RTKN,CLIP1,SEMA6D,ASIC4,ST8SIA1,SLC1A7,RADIL,SLC20A2,UNC80,WDTC1,BDP1,SPP1,ERC1,UNC5B,ZC3H13,EPB41L3,TTBK2,KANK1,FBXW11,TBX15,VWA3A,ZFP90,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,CYB561A3,THRA,TJP1,KAT6B,PRMT8,STXBP4,DCBLD1,TSC1,FAM181B,VLDLR,XRCC4,GAL3ST3,FAM198A" MicroRNA hsa-miR-34b:PITA hsa-miR-34b:PITA_TOP PITA 2.01E-58 1.13E-54 7.16E-58 6.60E-57 117 379 "CLK4,CCDC85A,ADRB2,PCDH19,MARCH4,OGT,BRINP2,DDX3Y,DCAF5,CALM1,PTBP2,CCK,NEURL1,CDC42,ZMYM4,CFL2,FOXN3,CHN2,AHCTF1,MYRIP,PLCXD3,TOX,SPATA2,MBNL2,TENM1,EMX2,RCAN2,EPHA5,ERBB4,AMZ2,WAC,FGF14,FOXG1,FAM49B,NPTN,GABRG2,NCKAP1,CPLX1,ARFIP1,PCDH17,GHR,PCDH11X,RAB40B,GPD2,TDRKH,PCLO,C1orf94,ZHX1,FRMD3,BACH2,MIER3,IGF1,IBA57,KCNMA1,KIF2A,KLC1,PIK3AP1,MAP2,MEST,MIA2,NEXMIF,MYT1,OMG,GPR137C,CNTN3,PDE4D,PDPK1,PIK3CD,PLP1,LRP12,SCHIP1,KANSL1,RELN,PTPRD,PTPRE,ZSCAN2,SLC6A15,FIGN,AP1AR,SEMA6D,ATXN2,ELMOD1,SOX6,MRAS,SCAF8,NLGN4Y,CPEB3,MAGI3,CHD9,FNDC3A,SLITRK3,SEPHS1,TET1,RCOR3,SNAP25,SNCA,MYT1L,SOX11,ZNF423,ARHGAP26,TAB2,STAU1,ARHGEF9,ANKRD28,ADGRL3,TRIM2,PCDHB3,PUM2,AHCYL2,AKTIP,CSMD1,TRPS1,FLRT2,SF1,LAMP5,KAT6A,TIGD6" MicroRNA hsa-miR-330-5p:mirSVR_highEffct hsa-miR-330-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.28E-58 1.28E-54 8.12E-58 7.48E-57 164 743 "RALGAPA1,DGCR6,EMILIN3,SYS1,GPRIN1,ADARB2,PLEKHH1,ADORA2A,RNF150,KIDINS220,CASKIN1,ALAD,FAM135A,DOC2A,CDC42BPA,SUGT1P4-STRA6LP-CCDC180,PKP4,CACHD1,TMEM108,ALDH7A1,N4BP2L1,ATP6V1G2,BARD1,SEC11C,RGS9,NRP2,KSR1,CDC27,CDH8,RCBTB2,TMEM155,AKAP6,SLC25A27,CHD1L,GDA,CSF2RA,LRIG1,MICAL2,OSBPL3,NCAN,APPL1,GIT2,HEPH,DLG3,USP3,MED12,DTNB,ABCC5,DNM1L,EBF1,EDNRB,SGK2,ASB3,SORBS3,C3orf18,SRRM1,ERBB2,CEP78,TOMM40L,PPP1R1B,FGF1,FGF11,FGFR1,ANKFY1,ARFGAP2,MSANTD4,TPPP3,ARPP21,ZNF274,DISC1,IGSF5,WASHC2A,USP19,GGT7,HPGDS,ZNF638,PSRC1,GPD2,BTN2A1,ZBTB49,ATXN2L,IDH3B,ZNF181,IL11RA,LRRTM1,KIF5A,MAT2A,SYT9,MEST,CTNNA3,MYO7A,VWA2,SLC11A2,PAK3,PALM,PDGFRA,PLEC,PLTP,PURG,SCHIP1,SEPT4,PPP3CB,PKIA,CNTLN,BDNF-AS,C1orf109,NKAIN1,SLC25A48,OXR1,DBX2,BSDC1,EXD2,RORB,KCNIP2,SCN2A,TNFRSF19,ZFP2,SEC14L1,ITSN1,SH3GL3,MAGI3,FNDC3A,CTXN2,PAAF1,FAM81A,BTBD7,SLC22A4,ZFP1,SNRPN,UNC80,ZSWIM8,NPAS3,SSPO,ERBIN,STAU1,ZSCAN29,ELOVL4,ARC,TCF12,WDR7,RNF216P1,CRB1,ITGB3BP,CDH22,ENHO,CDK20,TPM3,PRMT8,UBE2H,AMOT,UGT8,SLAIN1,MTCH1,VLDLR,ELFN1,ZNF189,DHX33,LMAN2L,NAV2,PPP1R3F,SLC17A6,SMIM8,CASC15,ZNF248" MicroRNA hsa-miR-3198:mirSVR_highEffct hsa-miR-3198:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.49E-58 1.40E-54 8.86E-58 8.16E-57 153 651 "KCNH8,NCKAP5,SYS1,ERMN,PLEKHH1,CC2D2A,AMT,MYH7B,PKP4,APC,TMEM263,MARK4,ASPH,B3GALT2,ADAM23,CFLAR,BMP7,THSD7A,KALRN,CANX,KRIT1,ARHGEF2,LGI1,DIS3L,CHGA,CHN2,JAM2,LHX2,CPNE6,RAB33A,FBXO7,CNR1,MYRIP,IGDCC3,SLC35F1,SNCAIP,RGS6,VCAN,UBXN2A,KATNAL2,ARHGAP24,SCRN1,ARMCX4,DNAJC6,DDX46,DNM2,SLC25A18,DTNA,EBF1,EDN3,FRY,TMEM35A,KCNMB2,SRRM1,DENND4A,IGSF6,DUSP27,FAM198B,FABP7,TUBB4A,GORAB,FGF12,FOXM1,POMT1,OGA,ZNF44,ILDR2,ERAP1,KIAA1841,TCERG1,RAB30,GPD2,TDRKH,GRIA2,GRIA4,GRIN2D,RABL2A,IRAK3,RASSF8,SMAP1,USP54,NME9,LAMA2,MAP2,LAYN,MYO7A,NPTX2,PCSK5,PCSK2,ENPP2,PFKP,FAM216A,PMP22,STRN3,EPB41L4B,PKIA,SIDT1,TMEM260,ACSM5,ACSS3,ZNF793,SUSD4,FIGN,RFX4,RGS7,NUDT11,GLDN,ATAT1,FAM182A,ELMOD1,SHC4,FNDC3A,CNKSR2,ST3GAL3,RUFY2,ATF7IP,SNAP25,MBD5,SNRPN,SOX1,SOX2,CLUAP1,PEG10,MCF2L2,SRPK2,PBLD,SEPT8,ROBO3,CAMTA1,TBX15,EHBP1,DOCK9,HIF3A,FAM200B,CRB1,AP4E1,HEY1,TMPO,SYNPO2,KCNE5,MTCH1,CCDC14,P2RY12,GUSBP1,ZIC1,PLPP4,SLC26A10,LYPD6,CELF4,PARP6,WIPF2,FBXO36,CASC15" MicroRNA hsa-miR-1290:PITA hsa-miR-1290:PITA_TOP PITA 2.56E-58 1.44E-54 9.11E-58 8.39E-57 113 353 "DSCAML1,GALNT13,SORCS1,NLGN4X,PCDH19,OSBPL6,SEMA6A,UNC79,AMPH,LRFN1,ARHGAP5,ZBTB10,ATP2B1,BCL7A,CACNA2D1,CABP7,SPAG9,FMNL3,MAGI1,DLGAP2,SRSF11,NRXN1,FAM19A5,HECTD1,AKAP7,SLC4A7,CREB5,HAPLN1,PLCXD3,CTNND1,FAM131B,YTHDC1,SMG7,KIF19,DLG3,CPEB2,SLC12A6,PDCD6IP,FAM78B,DYRK1A,MBNL2,ABI2,ELAVL3,EN2,RCAN2,CLVS1,ACSL4,STAG2,C15orf41,MSTN,ARFIP1,GPR34,PSIP1,HAS2,MIER3,LRRTM3,KCNK2,KLC1,MAP2,NFIX,NKX2-2,PDE3B,NLGN3,PIK3C2A,LRP12,PACSIN1,POU3F2,MED1,MINDY2,WBP1L,SNRK,TMEM255A,RALGDS,OXR1,DPF2,PBRM1,KLHDC8A,ROBO1,FBXW7,AP1AR,ATXN1,FNDC3A,PPP4R3A,WDR47,SEPHS1,CCDC88A,BTBD7,ATF7IP,TMCC1,SP2,NKAIN2,STAU1,SYN1,CAMTA1,UNC5D,TCF4,CRTC1,HEY1,LRRC8A,WBP2,CADM1,FAM155A,SLAIN1,ZNF711,ZNF24,CELF4,ZNF189,CADM2,KCNAB1,RGS7BP,FZD3,KAT6A,FRMD6" MicroRNA hsa-miR-2277:mirSVR_lowEffct hsa-miR-2277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.70E-58 1.52E-54 9.61E-58 8.85E-57 151 635 "ACHE,OSBPL1A,GPRASP2,MRTFA,ANK3,PHF12,GPAM,PPFIA3,CDK10,SPTBN4,ARHGDIA,MARK4,N4BP2L1,ADAM15,BACH1,CACNA1G,CAMK2B,TRIM41,CAPN3,PRC1,DIS3L,RAB28,HECTD1,NIPBL,TMEM155,MAGED1,ABI3BP,IFFO1,CREM,HDAC9,GAPVD1,KCTD8,PLEKHM1,SV2B,SPOCK3,DLX1,DNM1,USP3,DPH1,DTNA,FIS1,AASDH,FRY,EIF4G2,TNK2,ELAVL4,ELN,TMEM35A,GPHN,EPS8,BAIAP2,CAP2,IP6K2,EVL,SGIP1,POMT1,TMEM107,GABRA2,SESN1,TCERG1,TNRC6A,GRIA2,RNFT2,ELOVL5,AGBL5,HSF2,CELF5,IDH3B,C5orf24,IL6ST,SCRT2,KCNK1,GATD1,PAXBP1,VWA5A,SYT9,LDLRAD3,LRP1B,CD200,PABPC1L2A,NNAT,DNHD1,GPR88,OGDH,OLR1,PKD1,PLXNB3,POLR2F,PPP1R1A,PRPH,PTPRO,ZMAT4,RET,REV3L,FIGN,ZFHX4,RORB,ACER3,RTKN,DGLUCY,SCG5,PPM1E,DOCK10,NTNG1,FAM81A,SLC8A2,EFHD1,SLC22A4,MBD5,USP33,KLHL7,PRRC2C,PLCB1,SYT4,ASTN2,C12orf76,CAMTA1,MLST8,CAMSAP2,TCF7L2,ZEB1,AZIN2,SYNE1,NAT16,DOCK9,PCDHB7,PUM2,TNS2,PCDHA5,RIMBP2,TP53BP2,TRO,DCBLD1,CADM1,CLEC2L,UGT8,CLDND1,GUSBP1,XRCC4,ZNF711,TRIM9,PRDM10,PCDH15,CAB39L,NELFE,UBE3B,SMIM8,CASC15,ADAMTSL3,RSPRY1,ZDHHC20" MicroRNA hsa-miR-491-5p:mirSVR_highEffct hsa-miR-491-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.85E-58 1.60E-54 1.01E-57 9.32E-57 162 727 "CPNE2,ABCF1,ASIC1,ARID1A,GALNT16,PTCHD1,PCDH19,SPOP,AMPD3,LRFN1,PI16,PHF12,LGR5,SEMA4G,CDK13,ZBTB10,ATP2B2,MPDZ,BCL2L2,CACNA1D,DIRAS1,KALRN,TRIM41,CBR1,KYAT1,MTMR7,INA,ZMYM4,ARHGAP33,TIGD7,PLEKHB1,PPT2,TPP1,TJP2,ABCG2,DNAJB5,IQCK,CP,PNKD,MICAL2,GREB1,PUM1,GAPVD1,CENPL,GIT2,DNAJC6,DDX46,RHOBTB1,KIF19,GRIN3A,ATN1,EDN3,PHC2,FRY,C3orf18,TMEM35A,EPB41L1,EPHA5,SIRPB1,ACTL6B,PCYOX1,EVL,SGIP1,ZNF605,PRELID3A,GAP43,SEPT9,INPP5K,ARFIP1,ZNF276,COPS8,TNRC6A,INSM2,TDRKH,KAT7,CELF3,IDH3A,ZNF546,RBPJ,IGSF1,NME9,KCNA6,KCND3,KCNJ3,KCNMA1,LAMP2,MAT2A,MDM4,MEIS2,MOG,GIT1,NF1,IGSF11,OGG1,PCSK5,CDK18,PDGFRA,PFKFB2,FAM218A,MAPKAP1,RC3H2,SH3KBP1,PKIA,PRKCG,HYDIN,SLC22A23,MDGA2,PYGM,RASGRF1,SEC61A2,MRAP2,ABCA11P,DGLUCY,SCN2A,SCN4B,COPZ1,SH3GL2,SH3GL3,SLC1A7,FAM214B,SLC8A3,NAPB,EFHD1,ATF7IP,SMARCC2,SORCS3,SMARCD3,WDTC1,MYT1L,FNBP1,IQSEC2,DDN,NFASC,ATP10B,SUPT5H,SYT1,TCF7,NAT16,ARHGAP9,CCDC173,SLC44A1,GALNT17,RGMB,PRMT8,RUNDC3B,TTC3,OSBP2,PLEKHH2,PORCN,CLDND1,RICTOR,KCNT2,MKRN3,ZSCAN26,DNALI1,GAL3ST3,KCNAB1,NELFE,ST7,NUP214,RNF170,CPNE4" MicroRNA hsa-miR-634:mirSVR_highEffct hsa-miR-634:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.64E-58 2.05E-54 1.29E-57 1.19E-56 154 661 "SLITRK1,SLC12A5,ERMN,PWWP2A,ESYT2,PTCHD1,ADRB2,AP2A2,PLA2G6,OGT,IGDCC4,ASPH,ATP2A2,ATP2B1,TTLL9,BACH1,BBS2,MPDZ,DCAF5,JAZF1,MMD2,CACNA1B,DDR1,SYT6,CBLN1,CCKBR,NRXN3,CLCN3,AKAP12,CRYM,FEZ2,PDE4DIP,CFAP61,GIT2,DDX46,RHOBTB1,G3BP2,WDR20,DLG2,PDCD6IP,DNM1L,EDN3,EDNRA,YAF2,ELAVL2,PLEKHA1,ING4,ELN,PAN3,EPB41L1,PIPOX,FAM198B,EFEMP1,PCYOX1,IQCG,FLT1,POMT1,SMC2,UFM1,DKK3,ARPP21,DBF4,GNAL,GPD2,LILRA2,NUDT21,GRIA2,GRIA4,ARHGAP36,IL11RA,INPP1,KCNJ11,KCNK2,STXBP5,HECTD2,ZFYVE27,MBD1,SRSF12,BLOC1S2,LYRM9,NASP,NCAM1,IDNK,NEUROD1,HCN1,PBX1,CCSER2,XRN1,PLCL1,LRP12,SEPT4,EPB41L4B,MED1,MINDY2,SNRK,PIGG,CNTLN,ANKHD1,TMEM260,PTPRG,RAD51D,RADX,ZYG11B,REV3L,SEC61A2,RNF220,ZFHX4,SETD5,CARF,FBXW7,ATP8B4,KCNIP1,RTN1,ATXN7,SCN8A,CPEB3,NTNG1,SHC4,CNKSR2,PPP4R3A,SLC12A2,CPEB4,MYH15,MBD5,SNRPN,PALLD,KDM4C,NPAS3,LMO3,CLASP2,TROVE2,ST5,DIP2A,ADHFE1,PRRC2C,ADAMTS17,SYN2,TBCEL,TMEM136,PCDHGA11,SYNE1,TGFBR3,CADM1,RPL7L1,BCL2L13,MEAF6,ZFP37,ZNF24,DHX33,NELFE,DOCK8,FRMD6,DPF3,ZNF30" MicroRNA hsa-miR-653-5p:TargetScan hsa-miR-653-5p TargetScan 3.76E-58 2.11E-54 1.33E-57 1.23E-56 126 444 "ABR,KLRC4,PLEKHH1,PTCHD1,BEND6,PCDH10,AMPD2,APC,LRRC4C,PPFIA3,ARHGAP5,CCDC74A,B3GALT2,BACH1,CAST,REPS2,DLGAP1,CDR1,MYL6B,CNR1,FAM171B,CLOCK,CS,PLCXD3,PYGO1,KIAA0513,PABPC5,ARMCX2,ELMSAN1,AK5,DPYSL2,EBF1,RBM12,ELAVL2,EIF1,EPB41L1,RCAN2,KATNAL1,MAD2L2,FOXO3,CELF1,FUT9,MPP6,PHYHIPL,NKX6-2,ATP8A2,GHR,PPARGC1A,RND1,LUZP2,PRRC2B,CECR2,RFFL,PRDM5,LINGO1,GUCY1A2,NXPH2,ARHGAP19,NCKAP1L,HLF,ELOVL5,HNF4G,NEGR1,AGFG1,IGF1,DOCK7,LIX1,IL6ST,INSM1,LRRTM3,CLVS2,KCNJ3,KIF2A,KIF5C,MDM4,MEIS2,POC1B,MTTP,MYO6,NCAM2,NOVA1,OPCML,GPR137C,CNTN3,PBX1,SCHIP1,MED1,PPP2R5E,PRKAB2,CEP41,DIRAS2,APTX,MDGA2,ANKHD1,EML5,PTPRG,GTDC1,RPRD1A,ROBO2,CSRNP3,ATXN1,SCN3A,FNIP1,HSPA4L,FHOD3,ANKRD6,MYT1L,NMNAT2,MCF2L,CLASP1,PSD3,NSD1,ITGB3BP,GPR161,HHIP,ASXL3,NR2C2,LRTM2,CADM1,LAMP5,DHX33,EVI5,PLSCR4,RTN4,MSRB3,PIANP" MicroRNA hsa-miR-550*:mirSVR_highEffct hsa-miR-550*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.82E-58 2.15E-54 1.35E-57 1.25E-56 134 503 "ARID1A,KLRC4,GALNT13,BEND6,NME5,SPOP,USP35,SRPX,PCDH10,CDC42BPA,DGKZ,PPP4R4,ZSCAN18,NUMB,ATP1A2,CA8,RUNX1T1,ZNF501,INA,SLC16A4,CDC27,LGI1,ZBED5,KMT2C,C2CD2,CRHBP,VCAN,SOCS5,APPL1,IST1,PITPNC1,ZEB2,RHOBTB1,DTNA,EDN1,FAM135B,FRY,FAM13A,PHF20L1,EML1,EPB41,RASGRP2,ANKRD13B,NCALD,TMEM74,ZNF585B,DLC1,SYNCRIP,OGA,ARPP21,DISC1,PCDH17,KDM2B,GNAO1,LILRA1,PRLHR,GRK4,TOX2,C1orf94,ZDHHC15,OPALIN,INSM1,ITPKB,KCNJ16,KCNN2,KIF2A,KIF5C,HECTD2,MAP6,MBNL1,EFHB,SHC3,MEF2C,MEIS1,SRSF12,KITLG,MID1,AFDN,MTTP,NCF2,GPR137C,PAK3,CNTN3,PCDH8,PDE4D,ZNF655,FAM218A,PRPSAP2,VPS13C,PTPRE,HKR1,CRTAC1,TTLL7,PCMTD2,RPE,ZNF568,CSRNP3,SFPQ,SH3GL2,NTNG1,NUBPL,ZNF365,SNRPN,MYT1L,NPAS3,SAMSN1,TTBK2,DIP2A,PLCB1,SYT4,C12orf76,CAMSAP2,ALG1,TCEA1,SATB2,DOCK9,USP32P1,CRB1,TMOD1,TMPO,RUNDC3B,TRPC3,TMEFF2,SGK3,AMOT,MEAF6,GUSBP1,TRIM9,ZFAND5,EMSY,PRDM2,PHTF2,MSRB3,SLC4A10" MicroRNA hsa-miR-943:mirSVR_highEffct hsa-miR-943:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.87E-58 2.18E-54 1.37E-57 1.26E-56 161 720 "ACADM,ASIC2,NBAT1,CSMD2,CCDC85A,BRAP,TXNDC16,LRRC7,USP28,CASK,TMEFF1,ASCL1,NUMB,B3GALT2,KIF1A,AZGP1,ADGRB3,JAZF1,LURAP1,CARS,SPAG9,P2RX6,SCARB1,DGKI,MAGI1,CFL2,JAM2,CLTA,IQCK,SLC4A7,ABI3BP,RTTN,ACBD5,SOCS5,ERC2,PUM1,FGFR1OP2,TOX,TMEM170A,CTIF,PABPC5,ARMCX2,DNAJC6,COPS7A,CEP170,PLPPR4,CDON,SLC25A18,DTNA,ANKRD46,PHF20L1,MRO,EPHA5,CEP85L,FCGRT,HPCAL4,ZMAT1,GABRB3,ILDR2,BRPF3,ZNF559,DISC1,MSTN,NFU1,MALT1,CRCP,RNPS1,PCDH11X,ZNF638,MAP7D2,PSRC1,PCLO,GRIK2,SPACA9,MAEL,ELOVL5,HNRNPK,NEGR1,HSP90AA1,SMAP1,PLD5,BRINP3,OLFM3,KLRC2,INSYN2,HECTD2,MAP2,LRP1B,PPM1L,MKLN1,MTTP,RSPO2,NF1,NOVA1,SLC11A2,NRCAM,NUCB2,GPR88,LOC100128398,SNTG1,PAK3,PDE3A,GNG2,FAM218A,A2ML1,XRN1,ST8SIA5,MTRF1L,PRIMPOL,PMP2,TRHDE,PRRX1,EPDR1,GRAMD1C,PSMD13,TMEM260,PID1,NWD1,ENOX1,ZNF493,RDX,ZMAT4,RFX4,RGS7,RPRD1A,RPL15,FBXW7,ZNF354C,ARX,CPEB3,NTNG1,CHD9,SEC31A,BTBD7,GKAP1,SMARCE1,DOK5,NEK4,RGL1,NSFL1C,MTCL1,FAM208A,CUX2,TCF12,CRB1,CDH22,ZFP91,NR2E1,TMPO,TRH,TRPC1,SGK3,XRCC4,FSTL5,ZXDA,PRTFDC1,EPM2A,CASC15,CAMK1G,KLHDC1,SLC4A10" MicroRNA "TTTGTAG,MIR-520D:MSigDB" "TTTGTAG,MIR-520D:MSigDB" MSigDB 5.29E-58 2.97E-54 1.87E-57 1.73E-56 106 310 "ADD1,SORCS1,PCDH19,HFM1,UNC79,MIER1,SEMA4G,IGDCC4,ATP2A2,ATP2B1,JAZF1,LRBA,CDH2,DCLK1,FOXN3,SYNPR,NRXN3,FAM19A5,QKI,NIPBL,SLC35F1,CDC42BPB,CRHBP,SOCS5,CNTNAP2,PUM1,HDAC4,TOX,DAPK1,DNAJC6,CPEB2,CASP8AP2,GOLT1B,MBNL2,EGR3,EIF4G2,UBE2E3,MEX3B,NBEA,GABRA1,GAD1,SALL3,PPARGC1A,GNAO1,GPM6A,GPM6B,GRM3,IL1RAPL1,KLF12,IGF1,HES5,BRINP3,ZNF385B,KCNK1,KCNMA1,STXBP5,MEF2C,HNRNPM,NCAM1,NPTX1,PDE4D,MAPKAP1,CDIP1,PPP3CA,DIRAS2,CNTLN,PTN,PTPRZ1,USP47,BSDC1,RDX,RFX3,RFX4,UBR7,ZFHX4,ATXN1,ATXN2,SCN3A,PPM1E,SLITRK3,SLC1A3,BTBD3,CPEB4,SNAP25,PDZRN3,USP33,SON,SOX1,SOX11,SP4,TAB2,SMOC1,SULF2,SYT1,TAL1,TCF7L2,SIRT1,TMPO,TRPS1,UBE3A,TBC1D15,RICTOR,FMN2,PRDM2,NAV3,JMJD1C" MicroRNA hsa-miR-647:mirSVR_highEffct hsa-miR-647:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.60E-58 3.15E-54 1.98E-57 1.82E-56 154 663 "ABHD6,NCKAP5,NBAT1,ARID1A,ADORA3,BEND6,HECW2,OSBPL6,ALCAM,AMPD2,ANK2,USP37,MIER1,TMEM263,RGS20,CCDC74A,CAPRIN2,CHRD,NCOA1,TTLL9,RGS9,SYNJ2,THSD7A,KALRN,CAMK2G,SYT6,CBR1,CERS5,TMEM257,CHGB,EPS15L1,IGFBP7-AS1,CLTC,NIPBL,ARHGEF6,IQCK,ARMC8,ZNF521,IGDCC3,MFSD4A,CHD1L,GDA,VAC14-AS1,DZIP3,CTH,CFAP61,RIMS2,RUBCN,KIF26A,DAPK3,USP3,NR1D2,CPEB2,FAM78B,ABCC9,FSD1L,OPTN,PHF20L1,ELN,TMEM35A,KCNMB2,RABEPK,ERCC2,ZIC4,EFEMP1,KAT8,GORAB,SEMA4D,CAMKK2,KHDRBS3,MSANTD4,MTHFD2,ATP8A2,GK,HPGDS,PCDH11X,DCLK2,CCDC184,GRIA2,PLCD4,GRM7,ZBTB49,LINC01551,SYNPO,AGBL5,HPCA,ICA1,INPP5B,KCNK1,KPNA5,LAMP2,HECTD2,FGFBP3,MEIS1,KITLG,CCDC80,FXYD6,NF1,NPY,NOVA1,ZNF827,PCSK5,PDE3B,PRRX1,MED1,MAPK7,GRAMD1C,PSMD13,PLPPR1,STK32A,PTPRB,IQSEC3,MSANTD2,ZYG11B,GTDC1,SEC61A2,ZFHX4,MEG3,ABCA11P,WLS,S100B,SCN8A,SEC14L1,SUPT20H,PAAF1,RAB3GAP1,ELMO2,SLCO1A2,OGDHL,SMARCD3,RCOR3,ANKRD36,MBD5,UNC80,NFASC,PBLD,SS18,SYNE2,ANO4,SIN3B,ZEB1,HIF3A,TEK,R3HDM1,TNR,C9orf85,METTL3,ZNF19,CA10,DNALI1,STOX2,SMIM8,NUP214,PIANP" MicroRNA hsa-miR-3187:mirSVR_highEffct hsa-miR-3187:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.16E-58 4.02E-54 2.53E-57 2.33E-56 148 615 "RALGAPA1,SYS1,KCTD16,OSBPL8,PCDH10,KCNT1,MAP4K3,SUGT1P4-STRA6LP-CCDC180,APBA2,UPRT,BCAS1,PLA2G4C,DDX3Y,ATP2B3,DPY19L3,ADGRB3,DST,SYNJ2,VXN,VSTM2A,CDC27,CFL2,CHM,CASC2,RAB33A,TPP1,CNTN1,SLC4A8,ZFP28,CRHBP,CS,VCAN,VAC14-AS1,SDC3,CTH,CTNND2,RUBCN,RIPOR2,LONRF1,DBI,YTHDC1,C8orf34,ZEB2,MYEF2,SV2A,WDR20,DNM1,USP3,E2F5,EDN1,EDNRB,C8orf37,SEZ6,TMEM74,CDKL3,F8,RACK1,FER,FGF1,FGF11,POLK,CAP2,MSANTD4,OGA,GABRA3,RAPGEF6,PPARGC1A,GLUL,PCDH11X,ZNF638,LOXL3,LNX1,GPD2,LINC00839,LINC01551,HPSE2,OPALIN,HSF2,RAB41,KCNJ3,STXBP5,SMAD1,MAP6,MATN2,MBNL1,NKX2-2,NUCB2,OGG1,PDE1A,GPR85,CCSER2,GPSM2,PLCL1,PLIN1,PDZRN4,PRRX1,CEP41,MAPK4,HYDIN,SPDL1,PTPRZ1,RADX,ZYG11B,TCP11L1,MAP6D1,CNTNAP3,ZNF331,ATXN7,SCN7A,NLGN4Y,SH3BP2,SH3GL2,FRMPD1,ASAP3,RUFY2,ATF7IP,CDK5RAP2,MYH15,SNRPN,SOX2,SPATA7,SP4,ERBIN,ZSCAN29,VPS13A,TMEM150C,TACC1,TBL1X,ANO4,SIRT1,C18orf54,TLL2,RBFOX2,WBP2,PRMT8,AMACR,TRO,PPIL6,UGT8,VLDLR,TRIM9,ZNF540,CSDE1,PRDM10,PCDH15,NELFE,TRAM2-AS1,ZNF248" MicroRNA hsa-miR-153:PITA hsa-miR-153:PITA_TOP PITA 7.39E-58 4.15E-54 2.61E-57 2.41E-56 111 343 "ASIC2,XKR4,USP31,OSBPL6,ANK1,USP28,APC,APP,AQP4,SEMA4G,CDK13,SLC4A4,BSN,LDLRAD4,CAMK2G,CANX,DLGAP2,CFL2,CLTC,CNN3,AKAP6,MFAP3L,KLHL3,DLG2,DMD,MAMLD1,DYRK1A,EFNA3,ELAVL2,SCML2,ATP8A1,TESK2,NPTN,CAMKK2,DOT1L,GATM,PPARGC1A,GLS,TNRC6A,PCLO,RNF165,MAP4K5,ARHGAP19,MIER3,C5orf24,SCRT2,KCNA1,KCNA6,KCND1,KCND2,IPO5,STXBP5,MAT2A,MATN2,SCAMP5,MITF,TAGLN3,ZC3H12B,NEUROD1,NEUROD2,NFE2L2,PDE3B,GPR85,PIK3R1,CCSER2,HMGCLL1,LRP12,PPP3CA,KANSL1,PKN2,PTCH1,PTPRD,RIC8B,ROBO2,RYR3,SFPQ,SLC1A2,FAM81A,WDR47,EPC1,GKAP1,SNAP25,SNCA,PALLD,SOX11,PLCB1,SYN2,SYT1,TCF4,DMXL2,CUX2,ZFPM2,TJP1,HEY2,SGK3,PITPNB,FLRT2,WIPF1,SPHK2,DPYSL5,LAMP5,SLC30A3,CADM2,PRDM2,SLC38A1,PRDM10,NAV3,WIPF2,RGS7BP,FZD3,UBE3B" MicroRNA hsa-miR-187:mirSVR_lowEffct hsa-miR-187:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.89E-58 4.43E-54 2.79E-57 2.57E-56 160 715 "DGCR6,GALNT13,SORCS1,CC2D2A,HFM1,CARNS1,ANK2,ANK3,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,LGR5,SHROOM2,AQP4,TMEFF1,STK33,DPY19L3,MIR9-3HG,ARHGEF7,GYG2,TRIM41,CBS,METTL6,USP6,CBFA2T2,CDH2,LGI1,CHGB,CHM,PPT2,COG1,TBPL1,CP,CRMP1,CLIP3,TRIM69,RGS6,SEC24C,ARHGEF10,ATRNL1,PLCH2,UBXN2A,EDRF1,ARHGAP32,RIPOR2,ZFYVE16,EARS2,PLPPR4,AK5,TMCC2,DPP6,DSCAM,DTNA,EDNRB,SEMA3D,KLHL5,YAF2,TNK2,PAN3,DCTN4,EPB41,EPB41L1,SLC43A2,ADGRV1,CLVS1,TMEM132C,ZMYND10,KAT8,SYNCRIP,FLNC,PSD2,EFCAB2,TACC2,SORBS1,APOPT1,KHDRBS3,STAU2,HHIPL1,DOT1L,TVP23A,MEGF10,DISC1,LRRC37A6P,MYOZ2,GFAP,ZNF638,GRIA4,RFFL,GRIN1,ELOVL5,ZNF491,RBPJ,INPP5B,A1BG-AS1,KTN1,LAMP2,LYPLAL1,MARK3,MBNL1,SYT9,MEIS1,JAKMIP3,MTTP,MYO7A,FXYD6,NEUROD2,ALDH1L2,CNOT4,PCSK5,PRTG,PDE3A,PDGFRA,TRHDE,EXOSC10,FA2H,PPP3CA,MAPK10,BCAS3,PIGG,ZIK1,CCDC40,RPRD1A,ZFHX4,CCDC102B,TMEM156,AMER2,SGK1,R3HDM2,WDR37,BTBD3,SEPHS1,PDZD2,IZUMO4,IDI2-AS1,STAU1,CEP68,ANKRD28,WDR7,PCDHA5,AHCYL2,TEK,PMS2CL,TMPO,TPM1,TMEFF2,UCHL1,FLRT2,PLEKHH2,ELFN1,MKRN3,PRDM2,PRTFDC1,NT5M,CSDE1,STOX2,RNF103,MVB12B,PDSS2,JMJD1C,GAN" MicroRNA hsa-miR-4330:mirSVR_highEffct hsa-miR-4330:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.47E-58 4.76E-54 2.99E-57 2.75E-56 163 741 "RALGAPA1,KCNH8,ACTN2,CSMD3,NDRG2,PTCHD1,ALCAM,OGT,ANK2,NUMB,DST,ST3GAL5,PTBP2,VXN,CAST,CLDN10,LDB2,CBFA2T2,LRRFIP1,TAOK2,NRXN1,QKI,TMEM155,ARHGEF6,IQCK,BAG4,CHD1L,FAM171B,CLOCK,CREM,CS,CSF1R,FEZ1,PHF14,USP6NL,HDAC9,MATR3,DCC,PITPNC1,PLPPR4,ECM2,DYRK1A,ABCC5,GOLT1B,RBM12,PHF20L1,ELAVL2,PLEKHA1,EML1,RCAN2,VPS26C,EYA1,F8,ZIC4,RACK1,ZSCAN30,GORAB,FGF13,FGFR1,EFCAB2,UFM1,STAMBP,TRAF3IP2,GAP43,DISC1,GART,SESN1,PPARGC1A,LYVE1,COPS8,GOLGB1,LPAR4,RFFL,FAM222A,IRAK3,NXPH2,HNF4G,USP54,IL12A,ZNF678,INSM1,LRRTM1,KCNA4,KCNJ3,KCNJ16,KCNK1,STXBP5,INSYN2,MDM4,MEF2C,NEUROD1,NOVA1,DNHD1,CLDN11,CNTN3,ENPP2,GPR85,NOMO2,PIK3R1,RETREG1,PLP1,PMP2,CCDC144B,PRKACB,PKN2,GRAMD1C,HYDIN,SYTL2,SIDT1,PTN,PTPRB,PTPRZ1,RGS12,SLC25A36,NUDT11,PBRM1,RNASEL,RPRD1A,ROBO2,ARMH4,SPIN3,LGR4,CLIP1,NCBP3,TRAPPC13,ITSN1,SH3GL2,WDR37,DHX30,INTS9,ANKRD36,SOX1,SP4,MCF2L2,TAB2,KLHL7,COBL,SIN3B,SYNE1,PCDHB10,PCDHB7,ARL10,MTMR14,ZNF384,RUNDC3B,PRR18,UBE2H,ZNF709,KLC2,XRCC4,ZNF19,TRIM9,ZXDA,CSDE1,STOX2,PCDH15,FIP1L1,WNK3,PDSS2,RTN4,RNF170,FXR1,NETO1" MicroRNA hsa-miR-589:mirSVR_highEffct hsa-miR-589:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.96E-58 5.04E-54 3.16E-57 2.91E-56 148 616 "ACTN1,ACTN2,NDRG2,SORCS1,SLC24A4,GPR158,KIAA1324,SPOP,GPRASP2,PHYHD1,BCAS1,AQP4,CADPS,ASPH,NUMB,TMEM108,SYNJ2,SLC25A14,RUNX1T1,PRC1,ZNF501,CDC27,GPR37L1,FBXO7,QKI,HECTD1,CNTFR,MFSD4A,CHD1L,SEC31B,CRYM,RGS6,LRIG1,PDE4DIP,ERC2,PHF14,RIMS2,DOCK4,TOX,ZFYVE16,DNAJC6,FBXL5,CEP170,PLPPR4,AK5,FAM107B,DPYSL2,DSCAM,DTNA,DTNB,ANKRD46,CNNM1,PHF20L1,AASS,GOLGA7,SRRM1,TMEM74,RTN3,RCSD1,MRVI1,ABCA8,FCGR1A,FDFT1,MED12L,NBEA,PDLIM5,NPTN,ERGIC3,AP4B1,TVP23A,GALC,RAPGEF6,PCDH17,TNRC6A,GPT2,PRUNE2,LPAR4,GRIK3,NR3C1,KAT7,ELOVL5,LRRC75A,MSL1,NKD1,L1CAM,FGFBP3,NCOA7,MAN2A2,ZFYVE27,LYPLAL1,MAT2A,SYT9,LRP1B,AFDN,SESN3,MYT1,P2RY13,SEMA5B,RETREG1,PURG,MAGEL2,PPM1B,PPP1R1A,PKN2,HYDIN,TMEM260,PTPRN2,MRPS18A,RNASEL,RPRD1A,DCUN1D2,ROBO1,EPHA10,SPIN3,ATP8B4,ACER3,AMER2,LRFN5,ST3GAL3,ABLIM3,PPP4R3A,TTC17,TSPYL2,CLASP2,COLGALT2,ZC4H2,KANK1,SYN1,ANKRD28,ZEB1,TPCN2,USP32P1,SLC44A1,DDHD1,FAM124A,RIMBP2,TNR,TPM1,METTL3,STXBP4,PITPNB,MGAT5B,PLPPR2,TMEM237,TMEM163,MPPE1,WNK3,FZD3" MicroRNA hsa-miR-31:PITA hsa-miR-31:PITA_TOP PITA 1.13E-57 6.34E-54 3.98E-57 3.67E-56 92 229 "ABR,CLK4,ARID1A,NDRG3,ADCY6,RTL9,APBB2,APP,NUMB,CCAR2,JAZF1,CACNB2,CALM1,CAMK2G,SYT6,FMNL3,ARHGEF2,CHM,CLCN3,QKI,PREPL,TENM4,CTNND2,DCAF8,FRMPD4,RIMS3,RHOBTB1,SRGAP3,G3BP2,FAM135B,RBM12,EIF5,SLC43A2,ATP8A1,TESK2,FOXO3,ANKFY1,AFF2,TACC2,KHDRBS3,STAU2,ZNF512,AHCYL1,GRB10,MAP4K5,ATXN2L,BACH2,CAMK2N2,CHIC1,AFF1,HCN1,IGSF11,PC,GDAP1L1,PIK3C2A,RETREG1,CDIP1,PPP3CA,TMEM260,FAM120C,TMEM145,PEX5,PRRT2,SNX22,SEMA6D,SCN2A,ELMOD1,PPP1R9A,WDR37,SLC1A2,SEPHS1,SOX11,CLASP2,KANK1,PLCB1,TACC1,EHBP1,SATB2,TCF12,TEK,DICER1,CSMD1,TNS1,ZNF384,NR2C2,FNDC5,KCNE5,OSBP2,SYNC,WNK1,FZD3,RTN4" MicroRNA hsa-miR-202:mirSVR_highEffct hsa-miR-202:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.13E-57 6.37E-54 4.00E-57 3.68E-56 156 683 "SDE2,XKR4,ADD2,KIAA1211,PTCHD1,INTS2,MRTFA,MAP4K3,DGKZ,TNRC6C,AQP4,PPP4R4,ZBTB10,ADAM23,BCL7A,SYNJ1,SYNJ2,CASTOR3,NIPA1,OSGIN2,BSN,CACNA1E,CCKBR,AIFM1,L3MBTL4,CIART,MS4A7,NDST3,TPP1,ARMC8,ABI3BP,RCHY1,CREM,SEC24C,VCAN,CNTNAP2,CX3CR1,ZFYVE16,ZC3H11A,CPEB2,DRP2,WDPCP,SEMA3D,RBM12,YAF2,FAM13A,TMEM35A,STARD3NL,PLEKHO1,RABEPK,GMPR2,DLC1,FHL1,CAP2,IP6K2,NELFCD,AKAP3,ATP6V1H,ATP2C1,SARAF,GABRG2,ILDR2,GAD1,SULT1C4,GHR,PPARGC1A,RAB40B,GRIA2,GRIA4,PLCD4,PSIP1,HAS2,KLF12,HMGB1,ZDHHC15,SMAP1,IRF8,MYLK2,IL12A,SLC35G1,KCNC2,KCNK3,KIF2A,IPO5,LAMP2,LIMS1,HECTD2,MEIS1,MEIS2,MOBP,MTTP,MYCN,NAP1L1,CNOT4,PCBP3,GPR137C,GNG2,XRN1,PURG,TRHDE,EPB41L4B,LRRN3,GDPD1,LAMA1,TMEM260,PTPRD,PTPRG,PTPRO,PPP2R3C,PLEKHB2,RASGRF1,RASGRF2,SLC25A36,RAVER2,CARF,ACER3,AMER2,ATXN2,CPEB3,DZIP1,SLC12A2,CPEB4,NAXD,SPATA7,SOX10,HECW1,KIF1B,NPAS3,TAB2,ST5,SULF2,PRRC2C,SYN2,SYT1,WASHC4,WDR7,SYNE1,DICER1,ERCC6L2,RBFOX2,ZNF384,ZNF709,ETNPPL,MICU3,ZNF540,SPIRE1,SMARCAD1,ZNF225,SLC30A4,ADAMTS9,HPS4,MVB12B,PHTF2,CASC15,NUP214,VANGL2" MicroRNA hsa-let-7a:mirSVR_highEffct hsa-let-7a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.12E-57 1.19E-53 7.45E-57 6.86E-56 169 798 "ARID1A,KLHL32,BRAP,ERMN,ADRB2,RTL9,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,CH25H,AIFM1,CHN2,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,OSBPL3,PDE4DIP,FRMPD4,DAPK1,B3GAT3,KLHL3,DLG2,DMD,CPEB2,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,GORAB,FGF11,FGR,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,PCDH11X,POLL,FUT10,CNTRL,ADAMTS8,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,IGSF1,DIPK1A,NME9,KCNC2,KCNJ3,KCNJ11,KCNK1,KIF2A,MDM4,MEIS2,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,OGG1,SNTG1,PDE3B,SERPINE2,FAM218A,XRN1,PRRX1,PKIA,GDPD1,MASP1,VPS13C,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,MEG3,MIR124-2HG,ATXN7,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,TCEA1,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,RICTOR,LYPD6,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-329:mirSVR_highEffct hsa-miR-329:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.39E-57 1.34E-53 8.41E-57 7.74E-56 157 695 "ADD2,LRFN2,AP2A2,HACE1,ADGRF5,MRTFA,PHF12,BCAS1,MIER1,RGS20,CAPRIN2,ASPH,EIF4G3,ATP1B3,BCL7A,DCAF5,BMPR1B,BTRC,CACNA1D,CALB1,PTBP2,TRIM41,SPAG9,ARHGEF25,KRIT1,ZMYM4,SOCS6,B4GALT6,PLAA,CLU,CLTB,ARHGEF6,COL9A3,IGDCC3,RBM39,CRMP1,RNF14,ABCG1,CSNK1G3,PDE4DIP,EDRF1,HDAC9,LONRF1,DAPK1,GNE,DYRK1A,EDNRA,SYT15,PHF20L1,SUGP2,EIF4G1,CALCRL,ENPP6,TOMM40L,ZSCAN30,FER,FGF12,SLC37A3,NBEA,POMT1,ST6GALNAC3,NRG3,DKK3,DISC1,WASHC2A,USP19,MALT1,MAP7D2,DCLK2,NR3C1,BTN2A1,LINC01551,PSIP1,RNFT2,MAP4K5,TNFAIP8L3,IGFBPL1,SMAP1,IL6ST,KCNC1,MARK1,POC1B,RTL5,NDUFA5,NF1,NPY,PCSK5,PDE4D,PDGFRA,OLA1,ZNF655,PLP1,MAPKAP1,PRKACB,SLC26A11,GON4L,PTPRG,FAM184A,OXR1,ERI2,ZDHHC4,ARHGEF10L,ZFHX4,CCDC102B,RPE,RPL15,MIR124-2HG,SEMA6D,LRFN5,LRRTM4,SCN8A,FBXO11,NUBPL,PAAF1,WDR47,CPEB4,ZNF667,CMTR2,SNRPN,KDM3A,SP4,ELOVL4,FGD4,SYN2,SYT4,TACC1,TCEA1,ZEB1,PCDHB10,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TIAM1,HEY1,ERCC6L2,R3HDM1,C5orf64,TRPC1,UBE2H,PLEKHH2,CLDND1,ZBTB14,SCG2,CIAPIN1,NAV3,UBE3B,KAT6A,HNRNPA3,PHTF2,NHSL1,CBLN2,FAM198A" MicroRNA hsa-miR-215-5p:Functional MTI Functional MTI miRTarbase 2.44E-57 1.37E-53 8.56E-57 7.88E-56 164 755 "CLK4,AS3MT,CDC7,OSBPL6,OSBPL8,C1QTNF3,ALCAM,PHF12,PKP4,APC,IGDCC4,TMEFF1,ASPH,ZBTB10,MTMR9,BARD1,BLM,DST,FUBP1,NIPA1,CA8,PTBP2,VXN,SPAG9,LRRFIP1,DIS3L,CFL2,CHM,B4GALT6,FAM189A2,TJP2,DNAJB5,AKAP7,FAM171B,PNKD,LRIG1,APPL1,CTH,EDRF1,DBT,ZEB2,COPS7A,BLOC1S6,FBXO25,KBTBD11,DYRK1A,EEF1A2,IRAK4,PCOLCE2,EML1,EPS8,CEP85L,EXTL2,CLVS1,CORO2B,ST3GAL6,TMEM164,MEX3B,SEC23B,SEMA4D,SMC2,KHDRBS3,SARAF,ZMYND11,SIGLEC8,GATM,FAXC,KCNMB4,RAB40B,PSRC1,GPR19,GPR37,CIT,PTPRT,FAM222A,ARHGAP19,ELOVL5,FAAP20,ZIC5,LRRCC1,USP54,IL6R,IL6ST,ZNF385B,ITGAV,SLC35G1,KLHL23,KIF5C,TTYH2,LIMS1,MAN2A2,MDM4,MEIS2,MXI1,SFR1,NUCB2,OPA1,CDK14,ANLN,SNX10,KCTD15,GPSM2,PRIMPOL,EPDR1,MAPK9,VPS13C,PTPRE,RAP1GAP,RADX,TRIM68,RET,RIC8B,RNASEL,RIMKLA,MAP6D1,CNTNAP3,RMI1,HES6,IL17RB,ASRGL1,ZFP30,FERMT1,ANKRD6,CLSTN1,WDR47,KDM4D,RADIL,ARHGEF40,SCMH1,ZFP1,FAM126B,EMC1,SSTR2,SS18,TBL1X,TCF7,DICER1,SIRT1,C18orf54,ZMAT3,TMPO,TPM4,ZNF346,TRPC1,TTPA,UGT8,PITPNB,USP1,BCL2L13,CCDC14,NSD2,ZBTB14,ZNF45,REEP1,ZNF184,EML6,WNK1,NT5M,LRP8,EPM2A,FAM182B,PHTF2,FBXO36,ZNF248" MicroRNA hsa-miR-877:mirSVR_highEffct hsa-miR-877:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.74E-57 1.54E-53 9.62E-57 8.86E-56 172 826 "CLK4,ADARB2,ADCY2,SLC12A5,ERMN,ADORA3,PCDH19,TAOK1,SMIM17,AMPH,ANK2,PKP4,UPRT,DDO,BCAS1,ATP2B1,DCAF5,CACNA2D1,CALB1,THSD7A,CAMK2D,KRIT1,USP6,NEURL1,C1orf52,CDO1,PLEKHB1,SYNPR,NDST3,NRXN3,CLCN3,KIAA1549L,TJP2,C4orf33,RCHY1,PREPL,HINFP,SUSD5,PDE4DIP,ZSCAN23,RUBCN,RIPOR2,FBXO25,SV2A,TMCC2,GRIN3A,DPYSL2,E2F5,FSD1L,SORBS3,C3orf18,EIF1,OLIG2,EPB41L2,EXTL2,ARMCX1,ATP8A1,CEP78,FGF14,FGR,FOXM1,STAMBP,ATP2C1,CELF1,OGA,GABRG2,AHCYL1,GALR1,GCNT2,GLDC,ZNF782,LILRA1,GRIA2,GRM8,MAP4K5,FRMD3,TNFAIP8L3,HMGB1,ZDHHC15,SHISA6,HTR2A,IGSF1,BRINP3,INPP5B,OLFM3,STXBP5,VWA5A,MAP2,SHC3,MMP16,MN1,MRPL42,NDUFA5,NELL2,NRCAM,OCRL,LOC100128398,ZNF827,CNTN3,ETFRF1,GDAP1L1,RC3H2,SCHIP1,ING3,MED1,PPP3CB,RASGEF1B,EPDR1,PSMA6,CNTLN,PTCH1,PTPRG,C1orf109,TTC13,ZNF615,MARCH1,REV3L,RFX4,RGS4,RGS7,RNASEL,RPE65,SEMA6D,SCN3A,MAGI3,FNDC3A,CCDC92,ZNF365,FAM214B,SLC6A1,RAB3GAP1,SLC8A3,SLC14A1,CPEB4,LMBRD1,SP4,NMNAT2,UNC5B,PEG10,C11orf87,TAB2,TROVE2,SSTR1,TTBK2,KANK1,PRRC2C,SYNE2,FNDC9,ROBO3,CAMTA1,ADGRL3,ATMIN,TPCN2,USP32P1,FRYL,AP4E1,ASXL3,TLL2,DAAM2,RIMBP2,AMACR,ZMYND8,KCNE5,RFTN2,PRR18,TUBB2A,PLEKHH2,BCL2L13,TBC1D15,NAV3,PDSS2,PHTF2" MicroRNA hsa-miR-4326:mirSVR_highEffct hsa-miR-4326:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-57 1.59E-53 9.96E-57 9.17E-56 152 654 "WDR35,C1QTNF3,ALCAM,PKP4,ANXA7,TMEM263,ASPH,MPDZ,RGS9,ST3GAL5,CAMK2G,RUNX1T1,MAGI1,CDO1,CHM,NRXN1,FAM149A,BTF3L4,CNRIP1,C2CD2,CREM,ATRNL1,VAC14-AS1,ERC2,GREB1,ECE2,HDAC9,GAPVD1,HDAC4,ZEB2,MED24,ALKBH8,RAB39B,DNAJB6,ABCC5,EDN1,FAM13A,GPR61,MBNL2,ELAVL4,ANKRD13B,ERBB2,DENND4A,CDKL3,ABCA8,CACNG2,TBC1D16,CHST15,FHL1,POLK,SYNCRIP,NBEA,STAMBP,MSANTD4,MEGF11,MEGF10,GABBR1,CAB39,GAD2,ARPP21,ALDH1L1,NFU1,ADAM28,COPS8,WDFY3-AS2,EML4,GRIA2,GRM5,AP4S1,MAEL,PADI2,ELOVL5,IDH3A,ITGA7,KCNB1,KLC1,ARHGAP12,LOC100128239,MAN2A2,ZFYVE27,MBD1,SYT9,SCAMP5,CTNNA3,RTL5,NCAM1,NTRK2,OGG1,PRTG,PDE4D,CDK14,CAMKV,HMGCLL1,LRP12,PRRX1,EPB41L4B,CEP41,PKN2,MAPK9,DCHS2,GON4L,STK32A,SLC25A48,RASGRF2,ZYG11B,REV3L,RFX4,SEC61A2,RNASEL,ROBO1,RPL15,ACER3,ABCA11P,TMEM156,ATXN2,SLC30A10,HKDC1,MAGI3,AMBRA1,CTXN2,DZIP1,SLC2A5,RUFY2,LRRC55,ZNF430,CDK5RAP3,IFT122,SP4,TAB2,CLSTN2,SSTR2,NKAIN2,TAC1,SIK3,DAAM2,TTC3,CLHC1,FAM155A,CCDC14,ZNF708,ZNF138,ZBTB16,SYNC,XKR7,EPM2A,DOCK8,UBE3B,HNRNPA3,CASC15,TRAM2-AS1,DPF3,SLC4A10" MicroRNA hsa-miR-98:mirSVR_highEffct hsa-miR-98:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.59E-57 2.58E-53 1.61E-56 1.48E-55 170 811 "ARID1A,KLHL32,BRAP,ERMN,ADRB2,RTL9,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,AIFM1,CHN2,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,ZNF385A,CREM,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DLG2,DMD,CPEB2,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,CAB39,GAD1,AHCYL1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,CNTRL,GRIA2,ADAMTS8,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,IGSF1,ZNF678,NME9,KCNC2,KCNJ3,KCNJ11,KCNK1,MDM4,MEIS2,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,GPR88,OGG1,SNTG1,PDE3B,FAM218A,XRN1,PRRX1,EPB41L4B,PKIA,GDPD1,MASP1,PTK2,SPDL1,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,ST6GALNAC6,MIR124-2HG,SEMA6D,ATXN7,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,HECW1,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,TCEA1,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,LRRC8A,FAM124A,TPM2,PDSS1,UBE3A,BEST1,RICTOR,LYPD6,ZSCAN26,SMARCAD1,SYNC,PRDM2,STOX2,WNK3,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-22-3p:TargetScan hsa-miR-22-3p TargetScan 5.03E-57 2.83E-53 1.77E-56 1.63E-55 125 446 "ACLY,EMILIN3,FMNL2,RNF150,AK2,PDZD4,BIN1,DPP10,PHF12,APBB2,ARRB1,CDK13,ASCL1,NCOA1,CADM3,MTMR2,CABP7,CAMK2G,BRSK2,FMNL3,AIFM1,DGKI,DLGAP2,GPR37L1,RAB3C,DNAJB5,CSF1R,RIMS4,KIAA0040,PLCXD3,HDAC4,IP6K1,CTIF,MAGI2,EDNRA,FEM1B,EMX2,EPB41L2,ERBB4,ETV1,DNAJC27,EZH1,CACNG3,ATP8A1,SEC23B,FAM49B,CELF1,FUT9,MEGF11,MTHFD2,GATM,GFRA1,KIRREL3,KCNMB4,CECR2,RAPGEF1,NR3C1,GRM1,GRM5,KAT7,PADI2,NXPH3,C5orf24,IL6R,KCNH1,MAT2A,ADAM11,MEIS2,PPM1L,MYO9A,NFYA,NTRK2,KCNK10,PALM,PAX6,OLA1,FTO,MAPK10,PROX1,RAB5B,KHDRBS2,DPF2,ERI2,GTDC1,RGS3,RIC8B,ALG9,ARMC5,FBXW7,GLDN,ACER3,HUNK,CSRNP3,PRCD,PPP1R9A,NTNG1,CHD9,CNKSR2,EPC1,KDM3A,ARHGAP26,DBNDD2,NPAS3,CAMTA2,NXT2,MAPK8IP3,MMS19,SATB2,ARHGEF12,ARHGAP9,ITGB3BP,GPR161,KAT6B,RBFOX2,PDSS1,CADM1,AMOT,CLIP2,KCNK12,MAP3K12,KAT6A,HNRNPA3,CAMK1G,PIANP,LAS1L" MicroRNA hsa-miR-221-3p:TargetScan hsa-miR-221-3p TargetScan 5.75E-57 3.23E-53 2.01E-56 1.85E-55 115 376 "RALGAPA1,ARID1A,AXIN2,PTCHD1,LRFN2,PITPNM2,PHF12,CAPRIN2,ASPH,INSYN2B,KSR1,ARHGEF7,MTMR2,CACNB4,PTBP2,RUNX1T1,CDH2,MAGI1,NDST3,KMT2C,QKI,NIPBL,AKAP5,OSBPL3,RIMS4,PLCXD3,RIMS3,CTIF,DNAL1,MYEF2,DLG2,CDON,DYRK1A,HIPK3,FRY,EGFR,PLXNC1,ELAVL2,RGS17,EIF1,EMX2,ERBB4,FGF14,GAB1,GABRA1,GBX2,RNPS1,GNAL,GPM6A,GPR12,GPR22,GRB10,GRM1,IL1RAPL1,MIER3,AGFG1,MSL1,IGF1,PLD5,CLVS2,KCNK2,KCNQ3,KIT,LIFR,HECTD2,MARK1,ADAM11,MDM4,MEIS1,MITF,DBNL,ADAM22,NAP1L1,NAP1L2,NOVA1,PDE3A,PIK3R1,PDZRN4,NXPH1,MED1,PPP2R5E,KANSL1,PKIA,MAPK10,ANKHD1,KHDRBS2,REV3L,FIGN,RFX3,ATXN1,KIF16B,CPEB3,FNDC3A,RPH3A,CCDC88A,MBD5,MYT1L,C11orf87,POGZ,MPRIP,AJAP1,C3orf70,FAM208A,CUX2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,FRRS1L,EML6,HNRNPA3" MicroRNA hsa-miR-222-3p:TargetScan hsa-miR-222-3p TargetScan 5.75E-57 3.23E-53 2.01E-56 1.85E-55 115 376 "RALGAPA1,ARID1A,AXIN2,PTCHD1,LRFN2,PITPNM2,PHF12,CAPRIN2,ASPH,INSYN2B,KSR1,ARHGEF7,MTMR2,CACNB4,PTBP2,RUNX1T1,CDH2,MAGI1,NDST3,KMT2C,QKI,NIPBL,AKAP5,OSBPL3,RIMS4,PLCXD3,RIMS3,CTIF,DNAL1,MYEF2,DLG2,CDON,DYRK1A,HIPK3,FRY,EGFR,PLXNC1,ELAVL2,RGS17,EIF1,EMX2,ERBB4,FGF14,GAB1,GABRA1,GBX2,RNPS1,GNAL,GPM6A,GPR12,GPR22,GRB10,GRM1,IL1RAPL1,MIER3,AGFG1,MSL1,IGF1,PLD5,CLVS2,KCNK2,KCNQ3,KIT,LIFR,HECTD2,MARK1,ADAM11,MDM4,MEIS1,MITF,DBNL,ADAM22,NAP1L1,NAP1L2,NOVA1,PDE3A,PIK3R1,PDZRN4,NXPH1,MED1,PPP2R5E,KANSL1,PKIA,MAPK10,ANKHD1,KHDRBS2,REV3L,FIGN,RFX3,ATXN1,KIF16B,CPEB3,FNDC3A,RPH3A,CCDC88A,MBD5,MYT1L,C11orf87,POGZ,MPRIP,AJAP1,C3orf70,FAM208A,CUX2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,FRRS1L,EML6,HNRNPA3" MicroRNA hsa-miR-4294:mirSVR_highEffct hsa-miR-4294:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.80E-57 3.26E-53 2.03E-56 1.87E-55 144 592 "NCKAP5,PLEKHG5,SLC12A5,ERMN,GRAMD1B,KCTD16,OSBPL8,CC2D2A,SPOP,OGT,SEMA7A,MYH7B,PHF12,SUGT1P4-STRA6LP-CCDC180,TMEM263,MARK4,BMP7,CAMK2D,CAMK2G,CANX,KRIT1,METTL6,CD86,DIS3L,JAM2,RCHY1,IGDCC3,C2CD2,RGS6,UBXN2A,CTNND1,DOCK4,KATNAL2,ARHGAP24,DAPK1,ARMCX4,ELMO1,DDX46,GNE,EBF1,SUGP2,RCAN2,SRRM1,IGSF6,ETV1,DUSP27,ADGRV1,GTF2IRD2,POMT1,STAU2,GABRA2,DISC1,KIAA1841,TCERG1,DBF4,TDRKH,GRM8,RABL2A,GUCY1A2,GUCY1B1,IRAK3,RASSF8,USP54,NME9,LAMA2,MAP2,MEIS2,MOG,MT3,TAGLN3,NELL1,NTRK2,ZNF827,PCSK5,FAM98B,SERPINE2,FAM216A,PMP22,RC3H2,SDK2,PKIA,TMEM260,ACSS3,SUSD4,ROGDI,RASGRF1,CARF,ROBO2,GLDN,SGSM1,ADAL,ATAT1,KCNIP2,FAM182A,SATB1,TNFRSF19,ELMOD1,SHC4,CHD9,FNDC3A,SLC14A1,ATF7IP,ANKRD36,SNAP25,SNCB,TNIK,CLUAP1,SRPK2,PBLD,SEPT8,SYN2,FAM208A,KLHL4,SATB2,ZEB1,TPCN2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,PMS2CL,AP4E1,TMPO,R3HDM1,TPM1,SYNPO2,RUNDC3B,CADM1,PITPNB,CCDC14,P2RY12,GUSBP1,SF1,PLPP4,CELF4,SPIRE1,SIGLEC10,WIPF2,CASC15,NHSL1" MicroRNA hsa-miR-432*:mirSVR_highEffct hsa-miR-432*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.29E-57 4.10E-53 2.55E-56 2.35E-55 144 593 "XKR4,PLEKHH1,HECW2,TXNDC16,PCDH10,SUGT1P4-STRA6LP-CCDC180,VAT1L,BCAS1,PPFIA3,DYNLL1,TMEM108,RIPK1,ADGRB3,BMP7,SYNJ2,CALB2,CHGB,CHN2,PLEKHB1,SYNPR,PLAA,C4orf33,IGLON5,SLC25A27,COL9A1,SLC4A7,SLC4A8,RTTN,HS3ST5,CRHBP,SLC32A1,LRRC3B,OSBPL3,DCAF8,TOX,NR1D2,DRP2,EDN1,ANKRD46,PHF20L1,EGFR,MBNL2,EXTL2,RACK1,RASL10A,ST6GALNAC3,PHYHIPL,GABRB1,ZNF234,MSTN,GPR162,HEPN1,CNDP1,GPD2,GPM6A,PCLO,GRIK3,GRIN2C,PTPN5,PTGDR2,MAN1B1,TNFAIP8L3,HMGCL,SMAP1,ITGAV,KCNC2,KCNJ5,KIT,KPNA5,VWA5A,SYT9,MEIS2,ADAM22,MYT1,SFR1,NELL1,LRIT2,NUCB1,OPCML,PDE3B,PDE1B,PDGFRA,CDK14,SPATA6,SH3KBP1,TATDN3,WDR25,PTK2,PXK,PTPRH,PTPRO,ZNF615,ENOX1,RASGRF1,CRTAC1,GTDC1,RIT2,ZNF532,PNMA8A,ZNF568,NCBP3,LRFN5,SCN3A,FAM19A1,TNFRSF19,ASIC4,ITSN1,MAGI3,CHD9,SLC6A1,SLC8A1,BTBD7,ATF7IP,MAST1,SORCS3,RIMS1,MBD5,CMTR2,HECW1,ATP10B,NKAIN2,MPRIP,FAM168A,CAMTA1,VWA3A,ZFP90,CLASP1,SIK3,FAM200B,DICER1-AS1,C5orf64,SEZ6L,SSBP2,CADM1,LAT2,TRIM9,EML6,PLPPR5,MEIS3,SLC30A3,CADM2,NAV3,SLC17A6,SSPN" MicroRNA hsa-miR-155-5p:Functional MTI Functional MTI miRTarbase 7.33E-57 4.12E-53 2.56E-56 2.36E-55 180 904 "FMNL2,ADD3,TBC1D14,FAM135A,LCORL,APAF1,APC,GPAM,ASPH,DDX3Y,BACH1,FUBP1,FOXK1,CARS,FMNL3,INA,AIFM1,CD81,CDH2,CFL2,SOCS6,CLTA,CLTC,CDC42BPB,CS,CSF1R,FEZ2,PHF14,PNPLA8,DOCK4,GAPVD1,MATR3,TOMM20,DBN1,CHRDL1,DMD,DMTF1,GOLT1B,EDN1,PHC2,EEF1A2,KLHL5,EGFR,ABI2,KCTD3,EIF4G2,C3orf18,EPB41L2,RTN3,EZH1,F5,FDFT1,SEC24B,POLR1B,PCYOX1,FOXO3,FLT1,ANKFY1,SPECC1,PDLIM5,ATP6V1H,SARAF,STAG2,CAB39,BRPF3,GALC,NCKAP1,MTHFD2,KIAA1841,GATM,ARFIP1,SPIN1,RAB30,GNAS,GPT2,GPM6B,NR3C1,KIF3A,PSIP1,PACSIN2,ACOT7,RBPJ,ZNF678,KCNN3,KPNA5,PAXBP1,SMAD1,TM6SF1,MEIS1,MEST,MIA2,MITF,MKLN1,MMP16,MOV10,MPP2,MXI1,MYO6,NASP,NOVA1,SLC11A2,OLR1,PCDH9,PDE3A,FAM98B,PIK3R1,STRN3,PSAT1,KANSL1,PPP5C,CEP41,PKIA,PKN2,FITM2,WBP1L,QRICH1,PTN,ZNF493,PBRM1,RPRD1A,CCDC82,DCUN1D2,FBXW7,RPS20,IL17RB,SOX6,HSPA4L,CHD9,CDK5RAP3,SHANK2,SLC12A4,CPEB4,SMARCA4,SMARCE1,PALLD,KDM3A,CLUAP1,SRPK2,TAB2,TROVE2,ERBIN,RGL1,GANAB,SUPT5H,SYNE2,SYPL1,ANKRD12,CAMTA1,EXOC7,WWC1,TMEM136,TCEA1,TCF4,TCF12,SIRT1,HHIP,ARL10,TJP1,TPD52,ZNF384,TRIO,TRPS1,ZKSCAN5,UBE2H,UGT8,VAV2,LAT2,RICTOR,XPO1,ZIC3,ZNF28,ZBTB38,WNK1,MFF,CIAPIN1,VPS35L,FIP1L1,CAB39L,HNRNPA3,ZNF248" MicroRNA hsa-miR-1308:mirSVR_highEffct hsa-miR-1308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.08E-57 5.10E-53 3.17E-56 2.92E-55 141 570 "ABHD6,KLRC4,SLITRK1,RNF150,SLC24A4,MTUS1,PCDH19,WDR35,OSBPL8,C1QTNF3,USP35,ABCD2,LCORL,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,SHTN1,TMEFF1,ZFYVE28,ASPH,NCOA1,MPDZ,FUBP1,CACNB2,CAMK2D,CAST,SLC16A4,CDH10,CCPG1,PLEKHB1,NDST3,PPT2,CNGA3,SUMF2,LETMD1,AKAP12,GDA,CSF2RA,DZIP3,ERC2,ZEB2,MAGI2,AK5,FAM107B,ARNT2,DLG3,CPEB2,DPYSL2,FAM13A,EPS8,SPEG,ACSL4,ZIC4,POLK,C1orf61,C2orf88,SMC2,PRELID3A,ST6GALNAC3,ZNF512,GABRA2,GALC,RAPGEF6,KIAA1841,PPARGC1A,RAB30,LOXL3,PLPP7,GRIK2,NXPH2,LINC01102,HNRNPK,IDH3B,KLRC2,TTYH2,KITLG,MITF,XRRA1,ADAM22,MYCN,TCEAL5,NFE2L2,NTRK3,NUCB2,CNTN3,PCSK5,PDGFRA,NLGN3,PIK3C2A,KCTD15,SLC25A23,RC3H2,PPARA,MAPK10,PROX1,CNNM2,VPS13C,PTPRB,TMEM231,MARCH1,ZYG11B,TRIM68,SETD5,ROBO2,SYNDIG1,ZNF568,TMEM156,SEMA6D,ELMOD1,IL17RB,SELL,CHD9,FNDC3A,FHOD3,BTBD3,CCDC88A,MBD5,TEX2,ZC3H13,TAB2,PBLD,ZSCAN29,ADAMTS17,TAL1,RPGRIP1L,TGFBR3,TK2,NR2E1,C5orf64,RBFOX2,TMEFF2,SLAIN1,LRP8,FAM47E,SLC17A6,RGS7BP,FAM13C,SMIM8,FBXO36,CASC15,ADAMTSL3" MicroRNA hsa-miR-455-5p:mirSVR_highEffct hsa-miR-455-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.88E-57 5.55E-53 3.45E-56 3.18E-55 155 685 "NCKAP5,ACTN1,XKR4,ADD3,CDC7,INTS2,KLHL13,RTL9,OSBPL1A,BBOX1,FAM135A,AMPH,LCORL,USP28,CNIH2,MIER1,ARNTL,CDK13,ASPH,DPY19L3,DCAF5,CFLAR,DST,CACNB4,THSD7A,CAST,LGI1,CLGN,SRSF11,MS4A7,LSMEM2,RAB33A,QKI,SRP14-AS1,TMEM155,COL4A5,RCHY1,CREM,VAC14-AS1,DZIP3,ERC2,PUM1,DOCK4,GPRASP1,ZFYVE16,ZNF337,MYEF2,FBXL5,AK5,KIF19,USP3,DNM2,DTNA,DTNB,PHF20L1,PLXNC1,ANKRD13B,ADGRV1,FGF12,FGF13,DACH2,AP4B1,OGA,GAD1,B4GALNT1,C15orf41,ACSS1,GHR,LOXL3,GPD2,GRIA4,PRDM5,KIF3A,TMEM25,GYG1,FRMD5,INSYN1,HMGCL,HTR5A,NKD1,IL6ST,JAK1,KLHL23,KCNK2,KCNN2,ARHGAP12,PIK3AP1,TM6SF1,JAKMIP3,ADAM22,MTTP,LAYN,NELL1,NF1,PAK3,PDE3B,PDGFRA,GPR85,CDK14,FAM218A,XRN1,PCDH18,PRRX1,NXPH1,PRKCZ,EPDR1,MASP1,VPS13C,GON4L,TMEM260,PTPN13,ATG16L1,CRTAC1,RFX4,RGS4,EXD2,GLDN,PTGR2,TRIM46,CPEB3,RAB3GAP1,KBTBD4,TET1,SORCS3,SNRPN,PDZD2,TNIK,STOX1,SS18,ERBIN,ELOVL4,KLHL7,SYNE2,CAMSAP2,SATB2,TCF7,WDR7,DOCK9,GPRIN3,ITGB3BP,CDH22,TJP1,FAM124A,STXBP4,PPIL6,NSD2,XRCC4,ZIC3,GPR158-AS1,ZSCAN26,SMARCAD1,LRP8,HPS4,HNRNPA3,KLHDC1" MicroRNA hsa-miR-206:PITA hsa-miR-206:PITA_TOP PITA 1.02E-56 5.71E-53 3.55E-56 3.27E-55 114 371 "RALGAPA1,SLC25A25,NDRG3,ADAR,FMNL2,INTS2,HACE1,MAP4K3,API5,BCL7A,FUBP1,BSN,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREB5,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,SMG7,DLG4,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,EPB41L1,RCAN2,EPHB1,SPEG,ZIC4,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,HNRNPK,SMAP1,IGF1,INSM1,KIF2A,KTN1,NAT8L,MEIS1,GIT1,NEXMIF,NEUROD1,HCN1,GPR137C,ZNF827,TMOD2,GDAP1L1,TRHDE,TNPO2,MED1,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,RGS7,RIT2,SLC25A36,CARF,FBXW7,SEMA6D,ASRGL1,MRAS,TRA2B,PPP1R9A,FNDC3A,SLC8A2,SNAP25,TMCC1,SOX5,SP2,LARP4,FGD4,SYN1,MTCL1,TAL1,ANO4,TRIM2,PUM2,DICER1,ZMAT3,TGFBR3,SLC44A1,LRRC8A,TPM3,FAM155A,UBE2H,AMOT,TBC1D15,TMEM178A,WIPF2,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA hsa-miR-1:PITA hsa-miR-1:PITA_TOP PITA 1.02E-56 5.71E-53 3.55E-56 3.27E-55 114 371 "RALGAPA1,SLC25A25,NDRG3,ADAR,FMNL2,INTS2,HACE1,MAP4K3,API5,BCL7A,FUBP1,BSN,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREB5,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,SMG7,DLG4,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,EPB41L1,RCAN2,EPHB1,SPEG,ZIC4,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,HNRNPK,SMAP1,IGF1,INSM1,KIF2A,KTN1,NAT8L,MEIS1,GIT1,NEXMIF,NEUROD1,HCN1,GPR137C,ZNF827,TMOD2,GDAP1L1,TRHDE,TNPO2,MED1,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,RGS7,RIT2,SLC25A36,CARF,FBXW7,SEMA6D,ASRGL1,MRAS,TRA2B,PPP1R9A,FNDC3A,SLC8A2,SNAP25,TMCC1,SOX5,SP2,LARP4,FGD4,SYN1,MTCL1,TAL1,ANO4,TRIM2,PUM2,DICER1,ZMAT3,TGFBR3,SLC44A1,LRRC8A,TPM3,FAM155A,UBE2H,AMOT,TBC1D15,TMEM178A,WIPF2,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA hsa-miR-493:mirSVR_highEffct hsa-miR-493:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-56 5.72E-53 3.55E-56 3.27E-55 152 660 "RALGAPA1,NCKAP5,ACTN2,ADD1,KIAA1211,ADORA3,AP2A2,RTL9,PKP4,ALS2,ARRB1,CADPS,ASPH,PCDHGB4,TMEM108,ATP1B3,ATP2B1,B3GALT2,ATP6V1G2,ADGRB3,DST,CACNB2,CAMK2G,CCKBR,INA,LRBA,CDC27,ZMYM4,LGI1,SRSF11,QKI,NIPBL,SLC4A8,SMARCAL1,ZFP28,FEZ1,GREB1,RUBCN,ECE2,HEPH,DMD,DTNB,FAM78B,DNM1L,EIF4G2,SORBS3,PCOLCE2,CALCRL,EPHB1,RABEPK,SPEG,MRPL37,ANKMY1,TLR7,GMPR2,MRVI1,AMZ2,ZNF589,FGF13,DACH2,TBR1,GAD1,CPLX1,RAB30,TNRC6A,ZNF638,KDM2B,LILRB4,NUDT21,CECR2,PCLO,GRM1,GRM2,SOX21,CELF3,NCKAP1L,HNMT,CELF5,GAREM2,JAK2,KCND1,KCNJ9,KIF5A,KIT,KTN1,MAOB,AFF1,JAKMIP3,TAGLN3,NKX2-2,DNHD1,OGDH,ZNF827,PBX1,PCDHGC3,PCSK2,PDGFRA,GNG2,ST8SIA5,PDZRN4,LRP12,GON4L,MDGA2,PTHLH,PXK,PTPRZ1,SUSD4,SETD5,KLHDC8A,PCMTD2,MCMBP,TCP11L1,ABCA11P,TRIM46,NUBPL,PAAF1,PKNOX2,SLC12A4,SMARCE1,RCOR3,SNRPN,HECW1,KDM4C,PEG10,ZNF302,ZSCAN29,SYN1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,WDR7,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,USP32P1,C9orf85,CLHC1,WIPF1,KCNT2,TRIM9,EML6,ADAMTS9,TMEM163,PAK5,ZNF30" MicroRNA hsa-miR-4309:mirSVR_highEffct hsa-miR-4309:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.03E-56 5.79E-53 3.59E-56 3.30E-55 148 627 "NCKAP5,SYS1,ERMN,PLEKHH1,HECW2,CC2D2A,AMT,MYH7B,PKP4,APC,CACHD1,TMEM263,ASCL1,MARK4,ASPH,B3GALT2,ADAM23,CFLAR,BMP7,KALRN,CANX,KRIT1,ARHGEF2,LGI1,DIS3L,JAM2,CPNE6,RAB33A,FBXO7,CNR1,IGDCC3,SLC35F1,HAPLN1,SNCAIP,RGS6,VCAN,UBXN2A,KATNAL2,GAPVD1,ARHGAP24,SCRN1,ARMCX4,DNAJC6,DDX46,DNM2,DTNA,EBF1,EDN3,FRY,TMEM35A,SRRM1,DENND4A,IGSF6,DUSP27,FAM198B,WAC,FABP7,TUBB4A,EFEMP1,FGF12,POMT1,DACH2,OGA,ILDR2,ERAP1,KIAA1841,TCERG1,TDRKH,GRIA2,GRIA4,RABL2A,IRAK3,RASSF8,HMGB1,SMAP1,USP54,NME9,LAMA2,MAP2,MAT2A,MT3,NPTX2,PAK3,PCSK5,PCSK2,ENPP2,PFKP,FAM216A,PMP22,STRN3,EPB41L4B,PKIA,SIDT1,TMEM260,ACSM5,ACSS3,ZNF793,SUSD4,FIGN,RFX4,RGS7,NUDT11,GLDN,ATAT1,FAM182A,ELMOD1,NTNG1,SHC4,FNDC3A,ST3GAL3,RUFY2,ATF7IP,SNAP25,MBD5,SNRPN,SOX1,SOX2,CLUAP1,PEG10,MCF2L2,SRPK2,SEPT8,ROBO3,CAMTA1,TBX15,EHBP1,DOCK9,HIF3A,FAM200B,CRB1,AP4E1,TMPO,SYNPO2,KCNE5,MTCH1,CCDC14,P2RY12,GUSBP1,ZIC1,PLPP4,SLC26A10,LYPD6,CELF4,PARP6,WIPF2,PDSS2,FBXO36,CASC15" MicroRNA hsa-let-7c:mirSVR_highEffct hsa-let-7c:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.11E-56 6.23E-53 3.86E-56 3.55E-55 168 798 "ARID1A,KLHL32,ERMN,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,AIFM1,CHN2,TAOK2,NDST3,C7orf61,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,MICAL2,OSBPL3,PDE4DIP,FRMPD4,DAPK1,B3GAT3,DLG2,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,PPP1R1B,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,POLL,GNAS,CNTRL,ADAMTS8,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,IGSF1,DIPK1A,NME9,KCNC2,KCNJ11,KCNK1,MDM4,MEIS2,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,GPR88,OGG1,SNTG1,SERPINE2,FAM218A,XRN1,PRRX1,POLR2F,PKIA,GDPD1,MASP1,BDNF-AS,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,RTKN,MIR124-2HG,ATXN7,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,BDP1,KIF1B,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,TCEA1,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,BEST1,RICTOR,PLPP4,LYPD6,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-1224-5p:mirSVR_highEffct hsa-miR-1224-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-56 6.56E-53 4.06E-56 3.74E-55 153 669 "CPNE2,RALGAPA1,CLK4,ABHD6,NCKAP5,ADORA2A,MAP4K3,USP28,UPRT,SEMA4G,MADD,DDX3Y,CFLAR,DST,ARHGEF7,GYG2,THSD7A,TRIM41,SYT6,RUNX1T1,CBR1,KRIT1,DGKI,CFL2,PPT2,COG1,TPP1,C4orf33,IQCK,COL11A2,ACBD5,CRYM,PDE4DIP,ERC2,PNPLA8,FGFR1OP2,RIPOR2,KIAA0513,AIF1L,C8orf34,KIAA0753,BLOC1S6,SPOCK3,SV2A,DYRK1A,E2F5,RBM12,GOLGA7,ELAVL2,GORAB,SPSB4,FGF12,ACTL6B,NOP56,DACH2,MEGF11,GALC,LRRC37A6P,SULT1C4,BRD8,CNDP1,GPD2,GPM6B,GSTM5,ZHX1,PACSIN2,HMGB1,GABARAPL2,HMGCL,MSL1,USP54,NME9,ITGAV,SLC35G1,CREG2,PIK3AP1,MAOB,MAP4,MBP,KITLG,MMP16,NODAL,NOVA1,GPR137C,PCMT1,PDYN,PFKFB2,NALCN,PRIMPOL,PRRX1,PRKACB,PRKCZ,MAPK10,BDNF-AS,PTPRB,PTPRG,TTC13,ZNF493,DBX2,ZDHHC14,GTDC1,ZDHHC4,RIT2,EMID1,LRRK2,PTGR2,DGLUCY,SEMA6D,SATB1,FNIP1,ITSN1,CTXN2,SEC31A,RUFY2,ZNF430,RCOR3,INAVA,RIMS1,UNC80,SON,CLSTN2,KLHL7,NUDT10,UNC5D,KLHL4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,CDH22,SEZ6L,TRO,TUBB2A,EIF4ENIF1,AMOT,UCHL1,ZNF17,ZNF138,ADAMTS9,MDH1B,ITM2C,SLC17A6,PLSCR4,FZD3,UBE3B,CASC15,DPF3,RNF146,SENP7" MicroRNA hsa-miR-613:PITA hsa-miR-613:PITA_TOP PITA 1.40E-56 7.83E-53 4.85E-56 4.47E-55 114 372 "RALGAPA1,SLC25A25,NDRG3,ADAR,FMNL2,INTS2,HACE1,MAP4K3,API5,BCL7A,FUBP1,BSN,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREB5,HDAC4,MATR3,AIF1L,MYEF2,ELMO1,SMG7,DLG4,DMPK,DTNB,E2F5,EDN1,CELSR3,EMX2,EPB41L1,RCAN2,EPHB1,SPEG,ZIC4,TAOK3,FGF14,IP6K2,NBEA,CPLX2,ARFIP1,PCDH17,ADGRA3,GPD2,PTPRT,RNF165,BACH2,HNRNPK,SMAP1,IGF1,INSM1,KIF2A,KTN1,NAT8L,MEIS1,GIT1,NEXMIF,NEUROD1,HCN1,GPR137C,ZNF827,TMOD2,GDAP1L1,TRHDE,TNPO2,MED1,MINDY2,MAPK3,WBP1L,PTPRG,SH3TC2,MSANTD2,RGS7,RIT2,SLC25A36,CARF,FBXW7,SEMA6D,ASRGL1,MRAS,TRA2B,PPP1R9A,FNDC3A,SLC8A2,SNAP25,TMCC1,SOX5,SP2,LARP4,FGD4,SYN1,MTCL1,TAL1,ANO4,TRIM2,PUM2,DICER1,ZMAT3,TGFBR3,SLC44A1,LRRC8A,TPM3,FAM155A,UBE2H,AMOT,TBC1D15,TMEM178A,WIPF2,WNK3,HNRNPA3,TIGD6,GAN" MicroRNA hsa-miR-640:mirSVR_highEffct hsa-miR-640:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-56 8.96E-53 5.54E-56 5.11E-55 163 756 "TKTL1,INTS2,GPRASP2,ANXA7,TNRC6C,LGR5,ARRB1,PLA2G4C,MARCH3,CAPRIN2,ADGRB3,DST,BSN,CA8,SYNPR,EPS15L1,CLTC,QKI,IGLON5,CNR1,ANKRD35,SLC25A27,MAGED1,ABI3BP,ACBD5,SEC24C,CYBB,DOCK4,ZFYVE16,PABPC5,ZEB2,ZBTB24,TIAM2,CEP170,MAGI2,ZC3H11A,RABGAP1L,ARNT2,GRIN3A,DTNA,DYRK1A,E2F5,AASDH,EIF5,RASGRP2,EPHA5,ENPP6,EXTL2,DLC1,GORAB,CAP2,ANKFY1,PSD2,COQ5,SORBS1,USP16,OGA,GALNT15,GALC,DISC1,SULT1C4,GLI2,CNDP1,GPM6B,NUDT21,RAPGEF4,STMN2,GRID1,GRIK2,RASSF8,C1orf94,KCND1,KCNH2,KCNMA1,LAMP2,VWA5A,HECTD2,LSS,PIK3AP1,MBNL1,POC1B,MITF,COL28A1,ADAM22,MXI1,NCAM1,NELL1,NF1,NOVA1,CHAMP1,PDYN,HERC2P3,ABCB1,PIK3C2A,PSAT1,PRRX1,PPP2R2C,PKN2,MDGA2,PIGG,BDNF-AS,TMEM260,PTPRD,ARID4A,RPRD1A,PCMTD2,NEK11,PTGR2,ATAT1,WLS,ITSN1,SH3GL2,FBXO11,WDR37,ZNF365,BTBD3,SLC9A5,SLC15A2,ATF7IP,SMARCA4,TMCC1,SCN3B,DOP1A,KDM4C,NFASC,NKAIN2,CEP68,KANK1,GANAB,FGD4,TBCEL,ANO4,WSCD1,TCF4,ARHGEF12,PUM2,FAM200B,DICER1,BHLHB9,ZFP91,BEX4,TPM1,METTL3,AMACR,ZMYND8,TSN,ANKRD20A2,ANO5,UGT8,VLDLR,SLC13A3,PCDH20,ZNF23,UPF3A,WNK1,EMSY,CADM2,PCDH15,NAV3,URM1,FZD3,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-25*:mirSVR_lowEffct hsa-miR-25*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.71E-56 9.63E-53 5.95E-56 5.48E-55 161 739 "DPF1,SERPINA3,ADD1,SORCS1,UNC5A,AP1B1,LRFN1,ZFAT,ANK3,PPFIA4,APBB2,PHYHD1,BCAS1,SFMBT2,SPTBN4,CAPRIN2,NCOA1,ATP2B2,SLC16A4,ASIC3,TAOK2,DLGAP3,EPS15L1,NRXN3,PPT2,KIAA1549L,MYL6B,SMARCAL1,CLOCK,NCOR2,CSF1,TENM4,CSF2RA,MICAL2,PLCH2,CTNND1,MYADM,SPOCK2,TIAM2,HP1BP3,RPS6KL1,ARRDC4,PHF20L1,RASA4,EML1,EIF1,EPB41,KCNMB2,RTN3,ANKMY1,ABCA8,ZNF461,SCML2,FCGRT,FGF11,POLK,NOP56,TRIM16,DLL3,FYB1,INPP5K,C1QL1,GNAS,GPR17,GRIN2D,CIT,LINC00839,KAT7,ATOH8,UBE2QL1,HMGCL,FAM95B1,LRRC25,SLC6A17,INSM1,KHK,A1BG-AS1,LRRC4B,NCOA7,MAG,MAN2A2,AFF1,MOG,MT1M,MYH6,SFR1,NHLH1,SLC11A2,NUMA1,OGDH,PDE4A,PDE1B,PFKFB3,ZNF655,CCSER2,FAM216A,FTO,SMOX,FXYD1,SCHIP1,NKAIN4,PKN2,PRKCZ,GRAMD1C,PTPRG,CCDC40,RNASEL,YY1AP1,EPHA10,BAALC,ZNF331,FAM102A,FRMPD1,MYO18A,NTNG1,ST6GAL1,ST3GAL3,SLC22A4,SORCS3,RCOR3,ANKRD36,KIF13A,FAIM2,SNRPN,UNC80,FAM219A,TNIK,FNBP1,ZSWIM8,C11orf87,SYN1,KAZN,IQCE,VWA3A,TCF7L2,SYNE1,NSD1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,DICER1-AS1,LEFTY2,KCTD2,RASD2,TPM3,C9orf85,SMUG1,LGI4,ZNF708,FMN2,POLR3H,EMSY,DNALI1,HPS4,TRIM16L,MVB12B" MicroRNA hsa-miR-509-3p:mirSVR_highEffct hsa-miR-509-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-56 1.02E-52 6.27E-56 5.78E-55 144 597 "CDC7,BEND6,GPR158,TXNDC16,ARRB2,MARK4,ATM,ADAM23,DST,SYNJ1,MMD2,CALB1,PTBP2,CAMK2A,LOC730101,CHM,SYNPR,RCHY1,CSNK1G3,ATRNL1,SLITRK5,APPL1,KATNAL2,ZFYVE16,ZC3H11A,RHOBTB1,NTM,RABGAP1L,PDCD6IP,EDNRB,FCF1,PHF20L1,STARD3NL,CALCRL,EPHA5,ENPP6,NCALD,ANKMY1,NRN1,FAM198B,TAOK3,ATP13A4,CHL1,GAD1,AHCYL1,ARPP21,TCERG1,GNAO1,GRIK2,RNF165,FRMD5,VSIG4,LRRC75A,LRRCC1,IGSF1,BRINP3,TUBB2B,LRRTM1,KCNJ3,KCNMA1,HECTD2,MAT2A,MEIS1,KCTD6,JAKMIP3,MSRA,N6AMT1,ZNF92,NNAT,NME4,HCN1,NTRK3,PCDH9,ENPP2,SEMA5B,PIK3C2A,FAM218A,ST8SIA5,PLP1,NXPH1,DRAM2,PPP2R5C,PRKACB,PKIA,MASP1,GDPD2,PTPN13,PTX3,SH3TC2,FAT4,ZNF493,RASGRF2,ZYG11B,SEC61A2,SETD5,KLHDC8A,PNMA8A,RORB,ELP2,ABCA11P,WLS,CLIP1,FAM192A,SEMA6D,SFPQ,SH3GL3,ABLIM3,SLC1A6,SLC2A5,SEPHS1,SCMH1,SORCS3,PBLD,CLASP2,GANAB,ANKRD28,ATP11A,PJA1,EHBP1,TCF7L2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFP91,TMOD1,RIMBP2,TMEFF2,LGI4,ZIC3,TRIM9,ZNF138,SPIRE1,WNK1,STOX2,MDH1B,PCDH15,RGS7BP,TRAM2-AS1,NETO2" MicroRNA hsa-miR-1268:mirSVR_lowEffct hsa-miR-1268:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.01E-56 1.69E-52 1.04E-55 9.60E-55 158 716 "CPNE2,FAM43B,ADCY6,KIAA1211,KIDINS220,SORCS2,PLA2G6,MRTFA,ANK3,APBB1,PHYHD1,AQP6,CHID1,ATP1A3,ATP2B3,CDK5R1,JAZF1,CAMK2G,BRSK2,P2RX6,ARHGEF1,SCARB1,KCNAB3,EVI5L,NOG,GPR37L1,JAM2,KIAA1549L,FBXO7,WHRN,ABI3BP,AHCTF1,ZNF385A,ANKRD44,FAM131B,IP6K1,DGCR5,B3GAT3,HP1BP3,POM121,DNM1,DPH1,ACOT8,RCAN1,TOM1,SNX29,SYT15,SIDT2,EIF4G2,BSCL2,EML1,EPHB1,MRPL37,CACNG3,TMEM132C,SCML2,SPSB4,AGAP2,EFCAB2,POMT1,UFM1,TMEM151A,JPH4,SIGLEC8,ATP8A2,GFAP,ZNF276,POLL,GPT2,BTN2A1,MFSD2A,RABL2A,PADI2,MAN1B1,ATXN2L,VSIG4,SYNPO,CELF5,KNDC1,INPP5B,ITGAM,KCNJ4,KCNN2,LMO1,MAG,MAT2A,SYT9,LDLRAD3,MEIS2,KITLG,MITF,SCG3,MYO7A,SLCO1C1,NOS1,ODF2,ZNF713,ZNF827,PCMT1,CDK18,PDE2A,FTO,C11orf49,FA2H,PPP2R5C,PPP2R5E,PTPRN,ZNF493,ZDHHC14,FIGN,BAALC,STK32B,MEG3,STX1B,FOXRED2,ATXN2,HOGA1,TRIM46,ST6GAL1,NUBPL,CLSTN1,SMTN,PKNOX2,SLC6A8,SLC8A2,SLC11A1,SLC12A4,LGI3,CMTR2,ZHX3,ZSWIM8,UNC5B,MCF2L2,CAMTA2,SSTR2,INKA2,STXBP1,ADAMTS17,ARC,SYT5,ALG1,MGRN1,TNS2,HIF3A,AP4E1,GALNT17,C5orf64,PIK3R5,RASD2,TRIO,TSN,LAT2,ZNF19,TRIM9,LINC02210,DOCK8,RTN4,TTC7A" MicroRNA hsa-miR-431:mirSVR_highEffct hsa-miR-431:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.46E-56 1.94E-52 1.20E-55 1.11E-54 145 608 "SDE2,CCDC85A,SORCS1,PWWP2A,ABCD2,SUGT1P4-STRA6LP-CCDC180,API5,APP,MIER1,CCAR2,CHID1,ATP1A1,ATP2B1,DPY19L3,ADAM23,KALRN,CANX,LGI1,L3MBTL4,SOCS6,CHRM1,NRXN3,TPP1,CLTA,WHRN,BTF3L4,SLC4A8,TCEAL2,PNKD,AKAP12,RGS6,VCAN,PDE4DIP,GREB1,DOCK4,RIPOR2,ZFYVE16,RHOBTB1,SACS,SRGAP3,CHRDL1,USP3,DTNB,DYRK1A,KRBA2,TSPAN5,HIPK3,VPS13B,IGSF6,HSPA12B,CEP78,CHST15,FER,HPCAL4,IP6K2,FOLH1,ST6GALNAC3,MSANTD4,TRAF3IP2,DISC1,SULT1C4,DCLK2,GNAL,PSRC1,GPM6A,LILRA1,GRM1,GRM7,FAM107A,ADAMTS6,C1orf94,SMAP1,DIPK1A,KCNC1,KCNMA1,KCNN2,MBD1,MEIS1,MID1,XRRA1,GIT1,NRBP2,MYO9A,NAP1L1,NRCAM,HCN1,OXTR,SNTG1,PCSK5,PDE2A,PDE3B,PDE4B,XRN1,JAKMIP1,MTRF1L,PRIMPOL,PMP22,MDGA2,CNTLN,PTPRZ1,RAP1GDS1,RASGRF2,MSANTD2,EXD2,YY1AP1,CCDC102B,ATP8B4,TRIM46,SGK1,SCG5,CPEB3,PAAF1,PPP4R3A,LIMCH1,SON,CLUAP1,KDM4C,LMO3,KANK1,CAMTA1,CAMSAP2,ZEB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FRYL,DAAM2,TRO,RPL7L1,OSBP2,VLDLR,TRIM9,LYPD6,ZSCAN26,PRDM2,RNF103,WNK2,RTN4,PIANP,FRMD6,NETO1" MicroRNA hsa-miR-4305:mirSVR_highEffct hsa-miR-4305:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.99E-56 2.24E-52 1.38E-55 1.27E-54 132 506 "SYS1,PLEKHG5,CCDC85A,ERMN,PTCHD1,ZNF578,LRFN1,TTLL9,ADGRB3,OSGIN2,CACNB2,CALB1,LRBA,CDH8,LGI1,MAGI1,CFL2,SRSF11,AKAP6,HS3ST5,CLOCK,ENTPD4,CRMP1,PDE4DIP,PHACTR3,GAPVD1,C8orf34,ZEB2,GSDME,RHOBTB1,DMTF1,ACOT8,SEMA3D,FSD1L,FAM13A,ELAVL2,EIF1,FGR,SEC23B,FOXF2,PSD2,EFCAB2,POMT1,NRG3,GABRA1,ZNF44,ZNF559,ACSS1,FREM1,CBX1,GNAS,FERMT2,GRIA4,RASSF8,ZHX1,ARHGAP19,ICA1,FAM95B1,JAK2,KCND2,KIF5C,KIT,FGFBP3,MARK1,MBD1,MBNL1,AFDN,NEK1,SLCO1C1,NODAL,CNOT4,OCRL,PDE4D,ANLN,MTRF1L,ING3,IRX1,PPP2R5C,PROX1,PTHLH,PTPRG,PID1,RAP1GDS1,RASGRF2,FIGN,TTLL7,NUDT11,CCDC82,EXD2,ROBO1,ATAT1,GALNT10,CPEB3,EPN2,ZKSCAN3,ZFP1,DMRTC1,LIMCH1,PDZRN3,CAND2,UNC5B,SRPK2,NUDT10,ACSL6,TCF4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ATP13A2,SIRT1,ITGB3BP,DDHD1,BHLHB9,TMPRSS5,RFTN2,WIPF1,XPO1,ZNF711,MICU3,KCNT2,TMEM237,WNK1,EMSY,PCDH15,FAM13C,UBE3B,KLHDC1,RNF146" MicroRNA hsa-miR-1255a:mirSVR_highEffct hsa-miR-1255a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.15E-56 2.33E-52 1.44E-55 1.32E-54 155 692 "CLK4,KLHL32,PLEKHH1,KCTD16,PLA2G6,TAOK1,ADGRF5,SPOP,ALCAM,SUGT1P4-STRA6LP-CCDC180,GPAM,PDE8B,ASPH,NUMB,ATP1B3,ATP2A2,ADAM15,RGS9,ZNF599,LINC00906,CASTOR3,CAMK2G,VXN,RUNX1T1,ZNF501,INA,CFL2,CHGA,PLEKHB1,CNTN1,COL9A3,CSF1R,ARHGEF10,MICAL2,OSBPL3,DZIP3,CTNND2,ST18,ARHGAP24,TBC1D5,DAPK1,COPS7A,SV2B,AK5,HS3ST4,DPYSL2,SLC25A18,DYRK1A,ANKRD46,SUGP2,RTN3,TLR7,SIRPB1,FGFR1,SGIP1,ZCCHC17,OGA,HRASLS5,GABRG2,NEU3,TUBGCP4,CYP46A1,GNAL,WDFY3-AS2,GRIA4,PLCD4,GRIK4,MFSD2A,AP4S1,GYG1,ATXN2L,HNMT,IGSF1,LIX1,LRRTM3,SYTL4,MAP2,MOG,CD200,SCG3,P2RY13,ALDH1L2,NODAL,IGSF11,OPA1,ZDHHC22,GLIPR1L2,CDK18,RC3H2,ING3,SH3KBP1,PPP3CA,EPDR1,SAMD9,SIDT1,BDNF-AS,PXK,PTPRG,ZNF493,SLC6A15,RGR,RGS4,RNASEL,C12orf49,PNMA8A,NEK11,ADAL,WLS,S100B,ATXN2,SCN2A,SCN3A,PRCD,SGK1,ITSN1,NLGN1,PAAF1,SLC6A1,KANSL3,TTC17,SOX2,NMNAT2,KDM4C,DDN,ATP10B,SSTR1,ZC4H2,STXBP1,NECAB1,NUDT10,CAMTA1,SATB2,ZFP90,RPGRIP1L,SZT2,ZNF346,FNDC5,RPL7L1,UBE2H,UBE3A,DNAJC12,WIPF1,CLDND1,GPR158-AS1,CELF4,SLC30A3,PRDM10,HPS4,NAV2,SLC17A6,ST7,PHTF2,SSPN,RNF146,LAS1L" MicroRNA "CTACCTC,LET-7C:MSigDB" "CTACCTC,LET-7C:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7F:MSigDB" "CTACCTC,LET-7F:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7I:MSigDB" "CTACCTC,LET-7I:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7A:MSigDB" "CTACCTC,LET-7A:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7B:MSigDB" "CTACCTC,LET-7B:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7D:MSigDB" "CTACCTC,LET-7D:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7E:MSigDB" "CTACCTC,LET-7E:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,MIR-98:MSigDB" "CTACCTC,MIR-98:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA "CTACCTC,LET-7G:MSigDB" "CTACCTC,LET-7G:MSigDB" MSigDB 4.33E-56 2.43E-52 1.49E-55 1.37E-54 112 362 "PLEKHH1,UNC5A,ADRB2,KLHL13,PCDH19,ARHGAP20,BEGAIN,MAP4K3,GAS7,SEMA4G,IGDCC4,CHRD,NCOA1,SLC4A4,ATP2A2,ATP2B1,ATP2B3,ZNF583,ADAM15,BACH1,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,AHCTF1,IGDCC3,CRY2,LRIG1,OSBPL3,PPP1R16B,PLCXD3,SPATA2,BLOC1S6,DMD,CPEB2,SLC25A18,ARRDC4,DYRK1A,ABCC5,GOLT1B,E2F5,E2F6,RASGRP1,EGR3,GOLGA7,EIF4G2,CERCAM,LRRC17,FGF11,ANKFY1,DOT1L,DKK3,GALNT15,C15orf41,CYP46A1,GNAL,TMEM121B,CACFD1,ADAMTS8,DDX19B,SOWAHA,NKD1,IGSF1,SCRT2,MDFI,RSPO2,NAP1L1,NME4,NOVA1,PRTG,SSH1,PRRX1,MASP1,RDX,DPF2,FIGN,KCTD17,DCUN1D2,LGR4,SCN4B,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,IQSEC2,DDN,NFASC,CLASP2,NXT2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,CDH22,TNFRSF1B,TSC1,RICTOR,USP32P2,SMARCAD1,MEIS3,PRDM2,PARP6,VANGL2,SOCS4,GAN" MicroRNA hsa-miR-602:mirSVR_lowEffct hsa-miR-602:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.22E-56 2.93E-52 1.79E-55 1.65E-54 136 538 "ADCY6,PLEKHH1,PWWP2A,CASKIN1,C1QTNF1,PDZD4,PHF12,PKP4,CNTNAP1,PPP4R4,EIF4G3,CADM3,DPY19L3,TTLL9,DNAJC27-AS1,KSR1,ARHGEF7,CACNA1B,CALM1,SYT6,P2RX6,TIGD7,TAOK2,RAB33A,FAM189A2,TENM4,CSNK1E,PITPNM3,PUM1,DOCK4,MATR3,SV2A,HS3ST4,CASP8AP2,DNM1L,WDPCP,HIPK3,RCAN2,EPHB1,ADGRV1,ABCA8,TAOK3,SEC24B,FHL1,IP6K2,FOXM1,SORBS1,ADGRA1,CHL1,ERAP1,C15orf41,DISC1,CPLX1,ALDH1L1,TOX3,STARD3,DCLK2,GPM6A,CCDC184,GPR37,RAPGEF1,HNMT,HSPA1L,IL11RA,C2CD4C,KLC1,NCOA7,MARK1,ADAM11,MYT1,FXYD7,NAP1L3,NEUROD2,NKX2-2,NPTX1,PCDH8,CDK18,PDE4B,PDGFRA,ZDHHC8,NALCN,CCSER2,NLE1,FAM216A,SDK2,SPATA6,SH3KBP1,PTPA,PRKACB,WDR25,PTPRN2,RAD51D,DPF2,MRPS18A,RNF220,ZFHX4,SETD5,ATAT1,KCNIP2,ASIC4,TRIM46,ITSN1,MYO18A,SLC1A7,SLC6A11,SLC11A1,LGI3,ANKRD36,MYO16,USP33,FAM219A,LHPP,EPB41L3,ZSCAN29,KANK1,TACR1,TAL1,IQCE,DMXL2,CUX2,TCF12,DOCK9,FAM189A1,TMEM9,TP53BP2,SEZ6L,EIF4ENIF1,PDIA2,BCL2L13,VLDLR,ZFP41,SLC26A10,TMEM198,SPIRE1,WNK1,DOCK8" MicroRNA hsa-miR-1304:mirSVR_highEffct hsa-miR-1304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.46E-56 3.07E-52 1.88E-55 1.73E-54 165 780 "ACLY,KLHL32,PWWP2A,LRFN2,SLC24A4,KIAA1324,LRRC7,ANK2,GPAM,ALS2,CAPRIN2,DACT3,SLC4A4,ADAM15,MPDZ,CFLAR,SYNJ2,OSGIN2,BAIAP3,CACNA1D,CACNA1E,CACNB2,KRIT1,C1orf52,CD81,CHM,B4GALT6,JAM2,RAB33A,CLTC,FAM189A2,CNGA3,ARMC8,AKAP6,LETMD1,ZFP28,CLIP3,FEZ1,MICAL2,SOCS5,CENPL,AIF1L,GIT2,ZEB2,COPS7A,EXOG,DNM1L,E2F5,ELN,TMEM35A,EPB41L2,RTN3,FAM198B,PRMT5,KAT8,PPP1R1B,ZNF589,GORAB,BAIAP2,PSD2,ATP6V1H,KHDRBS3,JPH4,ZNF234,DNER,GLDC,GLS,PCDH11X,GNAL,ADGRA3,PRUNE2,MCHR1,GRIA4,GRIN2C,HMGCL,LRRCC1,PLD5,SCIN,DIPK1A,LRRTM1,KCNA2,KCNA6,KCNN3,KHK,LAMP2,ZNF667-AS1,MAN2A2,MBNL1,MEIS2,MID1,ZNF680,MYO7A,ZC3H12B,NINJ2,CNOT4,NUCB1,NUCB2,PFKFB2,GDAP1L1,TMIE,CCSER2,SNX10,SMOX,HMGCLL1,PRRX1,MBOAT7,SH3KBP1,POU3F2,RAB39A,SYTL2,GDPD2,ELOVL2,SPDL1,PTPRB,FAM120C,USP47,SH3TC2,UBR7,ROBO1,ACER3,MEG3,ZNF568,SATB1,LRFN5,SCN3A,LRRTM4,LINC00461,IL17RB,CPEB3,ABLIM3,SLC15A2,TET1,SMARCE1,SOX5,KDM4C,ZC3H13,DDN,NFASC,CLSTN2,TTBK2,AJAP1,SYT1,ZEB1,WDR7,GPRIN3,TIE1,HEY1,NR2E1,TMPO,C9orf85,ZNF384,RUNDC3B,TUBB2A,UGT8,ZFP41,LINC02210,MDH1B,NAV3,LINC00632,SLC17A6,PDSS2,GOPC,PHTF2,MSRB3,JPH3" MicroRNA hsa-miR-625*:mirSVR_highEffct hsa-miR-625*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.56E-56 3.12E-52 1.91E-55 1.76E-54 144 602 "RALGAPA1,SDE2,DPY19L2P4,SLC44A5,AP2A2,GPR158,OSBPL8,LRRC7,LRCH2,PKP4,ALS2,API5,LGR5,ARNTL,ASPH,ATM,MTMR2,OSGIN2,CACNA2D1,SLC25A14,LRRFIP1,LGI1,QKI,NIPBL,AKAP7,RCHY1,ANKRD44,SOCS5,PHF14,GREB1,ST18,HDAC9,DGKB,YTHDC1,DCT,ZNF804A,HP1BP3,DDX46,PLPPR4,DLG2,DMD,EDNRB,EIF4G2,PLEKHA1,LRRC17,SRRM1,DENND4A,ETV1,RRAGB,SCML2,ZSCAN30,PCYOX1,NPTN,STAU2,BRPF3,DNER,ARFIP1,HTATSF1,FERMT2,WDFY3-AS2,GPD2,RAPGEF4,ATP2B1-AS1,GRIA4,RFFL,GRM5,FAM19A2,PAXBP1,MAT2A,MEST,MXI1,NEUROD1,NF1,SLCO1C1,OPHN1,GPR137C,GPR85,PURG,PPM1B,PPP3CB,GRAMD1C,PTN,PTPRD,ZNF793,RALGDS,RAP1GDS1,RBBP6,RDX,SETD5,RAVER2,CARF,CCDC25,RORB,RPE65,TMEM100,BAALC,LGR4,SAFB,FAM19A1,SLC2A5,SEPHS1,ATF7IP,CPEB4,MYH15,KIF13A,UNC80,SON,PEG10,C11orf87,PBLD,CLASP2,CLSTN2,SSTR1,ZSCAN29,SEPT8,SULF2,GSE1,COBL,FAM208A,SATB2,WASHC4,RALYL,PCDHB3,ITGB3BP,RIMBP2,RGMB,RUNDC3B,ANKRD20A2,TMEFF2,CADM1,FLRT2,VLDLR,ZNF781,ZNF28,ZNF142,PLPPR5,EMSY,CADM2,TMEM163,WNK3,MVB12B,RGS7BP,NETO1,RNF146" MicroRNA hsa-miR-378*:mirSVR_highEffct hsa-miR-378*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.76E-56 3.24E-52 1.98E-55 1.82E-54 142 586 "SORCS1,ERMN,AP1B1,GPR158,WDR35,CC2D2A,ZNF578,AMT,GPAM,ATP1B3,BACH1,ADGRB3,ZNF599,DST,KALRN,ZNF501,AIFM1,RAB33A,RAB28,CLCN4,SUMF2,ZFP28,GDA,RGS6,CSF2RA,DZIP3,PHF14,CCDC144A,GPRASP1,ARHGAP32,DCC,DDX46,EXOG,NYAP1,DNAH9,DTNA,ABCC9,ANKRD46,SGK2,RASA4,EPHB1,ENPP6,EFS,MRPL37,F8,TMEM132C,TAOK3,FCGR1A,FGR,STAMBP,CAMKK2,ATP2C1,AP4B1,FAM184B,B4GALNT1,GALR1,ZNF559,WASF3,SRCAP,KIRREL3,TCERG1,DBF4,LOXL3,LNX1,GPR12,DHX35,SMAP1,HTR2A,EID2B,USP54,ZNF678,KCNJ9,KIF5A,INSYN2,SYTL4,SYT9,PPM1L,MMP16,MOBP,CCDC80,LYRM9,NDUFA5,HCN1,OPA1,OPHN1,PBX1,PDE1C,PLP1,PCDH18,TRHDE,LRP12,EPB41L4B,DCHS2,PTK2,PTPRN,PTPRN2,FAM66C,SH3TC2,ATG16L1,SLC25A36,CARF,ROBO2,PCMTD2,RPE65,TMEM100,SPIN3,TCP11L1,ABCA11P,TRAPPC13,ATXN2,LINC00461,SUPT20H,COPZ1,NLGN1,SLC1A6,WDR47,CCDC88A,KBTBD4,PDZRN3,UNC80,SOX3,BDP1,ZC3H13,NPAS3,LMO3,COLGALT2,SULF2,SMG6,DMXL2,WDR7,ERCC6L2,DAAM2,UBE2H,UGT8,WIPF1,ZNF781,FTSJ1,EMSY,PRDM10,C12orf4,HNRNPA3,VANGL2" MicroRNA hsa-miR-4303:mirSVR_highEffct hsa-miR-4303:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.29E-56 5.22E-52 3.19E-55 2.94E-54 160 739 "ACADM,ASIC2,ACTN2,KDM5D,SORCS1,PWWP2A,INTS2,LRRC7,ALAD,ZFAT,ANK2,SUGT1P4-STRA6LP-CCDC180,APC,TNRC6C,LGR5,ASPH,ATM,ATP2A2,BACH1,DST,SGCE,KALRN,PTBP2,INA,TMEM257,CDC25B,CDC42,TIGD7,CHM,JAM2,ZFYVE9,CNTN1,SLC4A7,TOGARAM2,ZFP28,RNF14,TRIM69,CSF2RA,ARHGEF10,MICAL2,PLXNA4,UBXN2A,ST18,MAML1,COPS7A,DDX46,EXOG,DRD1,RCAN1,EBF1,FCF1,ASB3,LRRC17,EFS,CDKL3,EYA1,F5,ST3GAL6,FCGR3A,FDFT1,FGR,CAMSAP1,SUCO,UBE2E3,FLT1,PSD2,SORBS1,STAMBP,ATP2C1,STAU2,GABBR1,GABRA1,GABRA2,GAD1,ARPP21,ALDH1L1,PCDH11X,LUZP2,PRUNE2,GRIA1,DIDO1,GRIA4,GRID1,FAM19A2,PSIP1,HMGCL,C9orf129,BTBD17,TJAP1,PLD5,C2CD4C,KCNK1,KCNK2,NAT8L,LDLRAD3,NCAM1,CNOT4,NUCB2,CLDN11,GPR85,OLA1,NLE1,PURG,DRAM2,PPM1B,NKAIN4,PIGG,STK32A,ACSM5,SLC25A48,RAD52,FAT4,RFX3,EXD2,RPE,ZNF568,ATXN7,SCP2,FNIP1,SCG5,KIF21A,FERMT1,SEC31A,SIRT2,SLC12A2,BTBD7,SNRPN,UNC80,SOX5,ZSWIM8,ZNF423,KIF1B,NPAS3,LHPP,ITPRID2,ZSCAN29,ADHFE1,KLHL7,NECAB1,SYNE2,RHBDL3,SLC37A2,MTCL1,DDHD2,SYNE1,TF,RELL2,TK2,RIMBP2,TPM1,SYNPO2,TRO,TRIM9,CELF4,LRP8,LINC02210,RNF103,RGS7BP,CASC15,SSPN" MicroRNA hsa-miR-106b*:mirSVR_lowEffct hsa-miR-106b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.11E-55 6.23E-52 3.80E-55 3.50E-54 137 549 "ACADM,CSMD3,SLC12A5,AP2A2,AMPH,AMT,DPP10,SUGT1P4-STRA6LP-CCDC180,EPB41L5,UPRT,VAT1L,LINC00173,NCOA1,RNF182,DST,SCAPER,C5,CACNB2,CAMK2A,CAMK2D,RHBDL1,CBLN1,MTMR7,SEPT7,LRRFIP1,TIGD7,B4GALT6,KIAA1549L,TJP2,CNN3,ARHGEF6,BTF3L4,SLC32A1,C1QL2,MICAL2,CNTNAP2,DZIP3,ERC2,RIMS2,ECE2,CCDC144A,CYBB,ARHGAP24,KIAA0586,PITPNC1,KIAA0753,DOCK2,DPP6,DSCAM,ABCC5,E2F6,EIF4G2,CALCRL,GPHN,TMEM74,F3,ACSL4,SLC9B2,OLFM1,AMOTL2,MEX3B,WDR83,FYN,BRPF3,GAP43,GPM6B,GRIA1,CACFD1,GRM7,SLC2A6,ATOH8,WIF1,ELOVL5,HPCA,BRINP3,ZNF678,KCNA4,KCNK2,KCNMA1,MATN2,LRP1B,KCTD6,GIT1,NCAM1,NEK1,NFE2L2,NRGN,NUCB2,ODF2,PCSK5,PFKP,PIK3R1,ING3,CRLS1,GRAMD1C,BCAS3,CNTLN,TMEM260,PTPRB,PTPRO,REV3L,RGS12,ROBO2,RPE,NEK11,SGSM1,YJEFN3,SATB1,ATXN7,PUF60,NTNG1,BTBD3,RAB3GAP1,SLC8A3,ARHGEF40,MTERF2,SMARCE1,RCOR3,RIMS1,SP4,MYCBP2,ZNF423,CLSTN2,NCDN,PJA1,EXOC7,TCF7L2,PCDHA2,CYB561A3,ITGB3BP,TMOD1,KCTD2,NUTM2A,LAT2,POLR3H,HRASLS,JMJD1C" MicroRNA hsa-miR-1255b:mirSVR_highEffct hsa-miR-1255b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-55 7.03E-52 4.29E-55 3.95E-54 152 672 "CLK4,KLHL32,PLEKHH1,KCTD16,PLA2G6,TAOK1,ADGRF5,SPOP,ALCAM,SUGT1P4-STRA6LP-CCDC180,GPAM,PDE8B,ASPH,NUMB,ATP2A2,ADAM15,RGS9,ZNF599,LINC00906,CASTOR3,CAMK2G,VXN,RUNX1T1,INA,CFL2,CHGA,PLEKHB1,COG1,CNTN1,COL9A3,CSF1R,ARHGEF10,MICAL2,OSBPL3,DZIP3,CTNND2,ST18,ARHGAP24,TBC1D5,DAPK1,COPS7A,SV2B,AK5,HS3ST4,DPYSL2,SLC25A18,DYRK1A,ANKRD46,SUGP2,RTN3,TLR7,SIRPB1,FGFR1,SGIP1,ZCCHC17,OGA,HRASLS5,GABRG2,NEU3,TUBGCP4,CYP46A1,GNAL,WDFY3-AS2,GRIA4,PLCD4,MFSD2A,AP4S1,GYG1,ATXN2L,HNMT,IGSF1,LIX1,LRRTM3,SYTL4,MAP2,MOG,CD200,SCG3,P2RY13,ALDH1L2,NODAL,IGSF11,OPA1,ZDHHC22,GLIPR1L2,CDK18,RC3H2,ING3,SH3KBP1,PPP3CA,EPDR1,SAMD9,SIDT1,BDNF-AS,PXK,ZNF493,SLC6A15,ERI2,RGR,RGS4,RNASEL,C12orf49,PNMA8A,NEK11,ADAL,WLS,S100B,ATXN2,SCN2A,SCN3A,PRCD,SGK1,ITSN1,NLGN1,PAAF1,SLC6A1,KANSL3,TTC17,SOX2,NMNAT2,KDM4C,DDN,ATP10B,SSTR1,ZC4H2,STXBP1,NECAB1,NUDT10,CAMTA1,SATB2,ZFP90,RPGRIP1L,SZT2,MTMR14,ZNF346,FNDC5,RPL7L1,UBE2H,UBE3A,WIPF1,CLDND1,ZNF17,GPR158-AS1,CELF4,PRDM10,HPS4,NAV2,SLC17A6,ST7,PHTF2,RNF146,LAS1L" MicroRNA hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA_TOP PITA 1.51E-55 8.47E-52 5.17E-55 4.76E-54 101 294 "CSMD3,ALCAM,FAM135A,DCAF5,CACNB4,CALM1,PTBP2,DCLK1,SOCS6,LHX2,NIPBL,AKAP6,CSNK1G3,PHACTR3,CTNND1,ST18,MATR3,RIMS3,CEP170,SMG7,SGSM2,RBM12,KMT5B,EGR3,RGS17,RCAN2,SEC24B,CAMSAP1,IP6K2,SALL3,NCKAP1,GATM,GHR,PPARGC1A,SPIN1,GLRB,TNRC6A,GPM6A,STON1,NUDT21,EML4,GRIA4,KLF12,BACH2,HNRNPK,IGF1,ZIC5,KCNMA1,IPO5,MBNL1,NEXMIF,PABPC1L2A,ZC3H12B,RCOR2,NFIX,PDE3A,GPR85,OLA1,ANKRD16,SCHIP1,NXPH1,KANSL1,CEP41,RAB39A,RELN,PTPRZ1,SH3TC2,OXR1,RDX,ZFHX4,RORB,SALL1,SOX6,SEPHS1,SLC12A2,NAPB,CPEB4,RCOR3,FAM126B,SOX5,LMO3,SS18,NECAB1,SYT1,CAMSAP2,EHBP1,TCF4,TRIM2,RPGRIP1L,PUM2,SIRT1,SLC44A1,RIMBP2,TPM1,TPM3,CLDND1,ZNF711,RNF103,SLC17A6,TIGD6,FRMD6" MicroRNA hsa-miR-4288:mirSVR_highEffct hsa-miR-4288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-55 8.73E-52 5.32E-55 4.90E-54 154 690 "RALGAPA1,SERPINA3,XKR4,PTCHD1,BEND6,INTS2,SPOP,ANK2,USP28,PHF12,CACHD1,AMER3,LRRC4C,ATP2A2,DPY19L3,ADAM23,ADGRB3,RGS9,SGCE,NFS1,ZBED1,MAGI1,TIGD7,CHRM1,KMT2C,PPT2,SLC4A8,ABCG1,SNCAIP,SEC24C,SIPA1L1,VCAN,FAM169A,SLITRK5,RIMS2,DDX46,NTM,EXOG,DYRK1A,E2F5,DCTN4,EPB41L1,DENND4A,RASL12,FAM198B,TUBB3,CEP78,CHST15,GORAB,FER,SUCO,FOXF2,IQCG,FLT1,ANKFY1,SORBS1,ZNF605,ST6GALNAC3,NSG1,GABRA2,C15orf41,DISC1,GFRA2,PPARGC1A,ZNF638,GNAO1,FUT10,RAPGEF1,PTPN5,PSIP1,GYG1,HSP90AA1,IDH3B,IGF1,SCIN,KCND2,MBNL1,SYT9,LRP1B,MEF2C,MMP16,ERICH3,MYO7A,PABPC1L2A,RCOR2,NTRK2,NUCB2,GNG2,PKD1,SNX10,JAKMIP1,PMP22,ING3,SEPT4,NXPH1,POLR2F,RAB39A,MAPK10,GRAMD1C,MASP1,SNRK,MDGA2,CNTLN,PTHLH,PTPN13,OCIAD1,PTPRE,TTC13,FAM66C,RASGRF2,RDX,SLC6A15,ZYG11B,RFX4,RPRD1A,CARF,ABCA11P,LRRTM4,CASC3,NLGN4Y,ITSN1,FAM81A,SLC6A8,BTBD7,CPEB4,SORCS3,DOP1A,PDZD2,TSNAXIP1,SP4,KDM4C,ZC3H13,LHPP,LMO3,PBLD,SEPT8,PHLDB1,C12orf76,DNMBP,ADGRL3,FBXW11,GPRIN3,FAM200B,AKTIP,HEY2,UBE2H,OSBP2,ZNF45,SLC26A10,LYPD6,EML6,PLPPR5,FAM13C,TIGD6" MicroRNA hsa-miR-587:PITA hsa-miR-587:PITA_TOP PITA 1.60E-55 8.99E-52 5.47E-55 5.04E-54 119 415 "ASIC1,ACLY,SLITRK1,GALNT13,SNX30,PTCHD1,PCDH19,C1QTNF3,FAM135A,PKP4,GPAM,API5,USP37,CADPS,MARCH3,ZBTB10,DDX3Y,SLC4A4,CACNB4,THSD7A,CALM1,LRBA,CDH10,B4GALT6,ARMC8,AHCTF1,SLC35F1,CREB5,CSNK1G3,CHD5,CNTNAP2,CTNND2,DOCK4,GAPVD1,FRMPD4,HDAC4,TOX,DAPK1,MFAP3L,MAGI2,ZC3H11A,SMG7,RAB39B,DMD,CPEB2,DYRK1A,ABI2,PLEKHA1,ERBB4,ETV1,AFF2,CHL1,GABRB3,GFAP,TCERG1,INSM2,EML4,GRIA2,GRM3,ADAMTS6,KLF12,MIER3,HNRNPK,NKD1,KCND2,MBNL1,MYO5A,NEUROD2,NKX2-2,GPR137C,PCDH9,PDE4D,CDK14,NALCN,NXPH1,MED1,MINDY2,CEP41,PKIA,USP47,ZFHX4,FBXW7,SYNDIG1,KCNIP1,FNIP1,TNFRSF19,SCAF8,SLC12A2,SLC20A2,SORCS3,MYT1L,SOX11,NMNAT2,CDK19,NKAIN2,ERBIN,RGL1,CAMTA1,TRIM2,USP22,SLC44A1,THRA,NR2E1,KAT6B,TPM1,TRPS1,CADM1,UBE3A,SLAIN1,MEAF6,NSD2,ZIC1,ZIC3,MICU3,SLC38A1,EVI5,URM1,MSRB3,FRMD6" MicroRNA hsa-let-7i:mirSVR_highEffct hsa-let-7i:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.68E-55 9.41E-52 5.73E-55 5.27E-54 165 786 "NBAT1,KLHL32,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,CALB2,TRIM41,AIFM1,CHN2,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,SLC25A27,AHCTF1,IGDCC3,MFSD4A,MICAL2,OSBPL3,PDE4DIP,FRMPD4,DAPK1,B3GAT3,KLHL3,DLG2,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,DISC1,DNER,GATM,CYP46A1,POLL,GNAS,GPM6B,CNTRL,ADAMTS8,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,NKD1,IGSF1,ZNF678,DIPK1A,NME9,KCNC2,KCNJ3,KCNJ11,KCNK1,KPNA5,MDM4,MEIS2,RSPO2,NAP1L1,CNOT4,NOVA1,GPR88,OGG1,HERC2P3,SERPINE2,XRN1,PRRX1,EPB41L4B,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTK2,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS3,RGS12,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,CLIP1,MIR124-2HG,ATXN7,FNIP1,KIF27,FNDC3A,RUFY2,TET1,KIF1B,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,BEST1,RICTOR,PLPP4,LYPD6,SMARCAD1,SYNC,CADM2,PRDM2,STOX2,WNK3,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-210:mirSVR_lowEffct hsa-miR-210:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.75E-55 9.86E-52 5.99E-55 5.52E-54 129 489 "CSMD2,ADD1,AP2A2,OSBPL1A,OSBPL6,C1QTNF3,MARCH4,LRFN1,AMER3,AQP4,CDK13,ASCL1,TMEM108,ADAM15,DCAF5,KSR1,BAIAP3,TRIM41,CBS,CCKBR,MTMR7,CACNA2D2,AKAP7,PCYT1B,MFSD4A,FAM171B,CSF1,TENM4,CSNK1E,USP6NL,NOS1AP,HDAC4,DNAJC6,SV2B,DNAJB6,ATL1,YAF2,SORBS3,EPB41L1,RCAN2,RAB9B,CEND1,MRVI1,SEC24B,FGF13,FGFR1,SCARA3,FOXF2,FLNC,NOP56,SORBS1,NSG2,ADGRA1,GABRB1,IP6K3,ALDH1L1,ADAM28,GLYR1,STARD3,DCLK2,GNAS,GPR17,NUDT21,GRIK2,ZBTB49,RABL2A,FAM222A,MAN1B1,TLX1,KIF5A,INSYN2,MAN2A2,MAPT,MBNL1,MEIS1,N6AMT1,CTNNA3,ZNF862,NEUROD1,NEUROD2,DNHD1,OXTR,SNTG1,PCDH8,PCSK5,PDE3A,POU3F2,CCDC144B,SIDT1,PTPRD,SUSD4,CRTAC1,PRRT2,RGS7,SEC61A2,RPE65,ATP8B4,MIR124-2HG,NLGN4Y,ITSN1,SLITRK3,MYO16,PDZD2,MYT1L,SOX2,LHFPL4,TAB2,TROVE2,SEPT8,MLC1,PRRC2C,ARC,CAMTA1,MGRN1,SIN3B,CLASP1,ARHGEF12,DICER1-AS1,ITGB3BP,AP4E1,PIK3R5,TPD52L2,ZMYND8,TMPRSS5,NSD2,NDRG4,SLC38A1,KAT6A,ZNF248" MicroRNA hsa-miR-449c*:mirSVR_highEffct hsa-miR-449c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.81E-55 1.02E-51 6.19E-55 5.71E-54 141 583 "RALGAPA1,KIDINS220,HECW2,TXNDC16,ALCAM,ABCD2,DPP10,VAT1L,TNRC6C,PRX,RGS20,ATP1B3,ADGRB3,PTBP2,USP6,CDH2,CDH8,LRRFIP1,CASC2,IGFBP7-AS1,CLTA,QKI,NIPBL,SLC4A8,ABI3BP,ZFP28,MFSD4A,CRHBP,FEZ1,PDE4DIP,DOCK4,GPRASP1,TBC1D5,KIAA0586,IST1,C8orf34,DDX46,G3BP2,GRIN3A,DNAH9,DRD1,ABI1,DTNA,MAMLD1,DNM1L,EDNRA,FCF1,EIF5,DCTN4,F8,CEP78,FER,POLK,CELF1,GABRA1,CHL1,ZMYND11,RAB30,ZNF638,FERMT2,RAPGEF4,ATP2B1-AS1,ADAMTS8,HNMT,HTR2A,OLFM3,KCNN2,KIF2A,STXBP5,MAOB,CHIC1,LRP1B,MMP16,MOG,CTNNA3,NF1,OGG1,LOC100128398,ZNF713,OXTR,PDE1C,SERPINI1,JAKMIP1,NXPH1,MINDY2,LRRN3,PPP2R5E,GRAMD1C,MTMR10,ELOVL2,TMEM260,VEPH1,KHDRBS2,RFX3,RGS12,RORB,ARMH4,FNIP1,SH3GL3,FBXO11,CNKSR2,NLGN1,NUBPL,SLA,MTERF2,SMARCE1,RCOR3,SNCA,SNRPN,PALLD,SOX5,KIF1B,NXT2,ADHFE1,SEPT3,KLHL7,CAMTA1,ALG1,ADGRL3,ZEB1,TRIM2,RPGRIP1L,SYNE1,TEX15,TLL2,ZFP91,NR2E1,TPM4,WBP2,TRO,STXBP4,TTTY15,PRR18,HEPACAM,XRCC4,ZNF74,LYPD6,FSTL5,ZSCAN26,LAMP5,RNF103" MicroRNA hsa-miR-3116:mirSVR_highEffct hsa-miR-3116:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.86E-55 1.05E-51 6.36E-55 5.86E-54 156 708 "EMILIN3,SORCS1,GRAMD1B,MTUS1,C1QTNF3,PHF12,PPFIA1,APC,MIER1,ARHGAP5,CAPRIN2,ZNF582,SLC2A11,CACNB2,KALRN,CAMK2D,MAP7,CCK,NOG,MS4A7,PPT2,C4orf33,SRP14-AS1,NIPBL,ARMC8,LETMD1,AHCTF1,MFSD4A,CLIP3,CS,RGS6,SEC24C,VCAN,FAM169A,CTH,RASSF2,DAPK1,DCC,PITPNC1,ZEB2,SV2B,SRGAP3,DMTF1,DSCAM,ECM2,SUGP2,KMT5B,ABI2,GOLGA7,SORBS3,EPHA5,EPHB1,RABEPK,ERBB2,TUBB3,GORAB,POLR1B,FGF11,FGF13,FGFR1,UFM1,B3GAT1,MSANTD4,MPP6,GABRA2,SRCAP,WASHC2A,RUNDC3A,ZNF276,TOX3,ADGRA3,GPD2,RAPGEF1,GRIN2C,VSIG4,CPT1C,OPALIN,HTR5A,IRF8,FAM95B1,NKD1,USP54,INSM1,NME9,KCND1,CYP27C1,PPM1L,MYO5A,PABPC1L2A,NCAM2,NF1,SLCO1C1,DNHD1,NRCAM,ZNF713,PDE3B,BEST3,PFKFB2,ZNF655,SNX10,MAPKAP1,ING3,FAT3,PPP3CB,PIGG,PTAFR,PTPRB,RAD52,NWD1,ZNF493,RASGRF2,ARID4A,FEZF2,RGS4,KIF7,RPRD1A,UEVLD,PRR5L,KCNIP2,CLIP1,SCP2,HES6,SOX6,KIF27,ZFP30,KIF21A,ST3GAL3,SORCS3,SMARCD3,RIMS1,SNRPN,UNC80,SON,SP4,GLT8D1,HECW1,RBM26,ADHFE1,CAMTA1,CUX2,SYNE1,USP32P1,FRYL,CYB561A3,TIAM1,MTMR14,TJP1,FNDC5,TSC1,ANO5,MEAF6,VSNL1,SF1,FSTL5,FBXO36,CASC15" MicroRNA hsa-miR-4252:mirSVR_highEffct hsa-miR-4252:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-55 1.18E-51 7.17E-55 6.60E-54 144 608 "TTYH1,ASPHD1,KDM5D,NDRG2,MTUS1,HACE1,OSBPL1A,HFM1,PHF12,UPRT,BCAS1,LGR5,ZNF583,ADAM23,BACH1,LINC00847,KSR1,BMP7,ARHGEF7,BTK,WASF1,CA8,KALRN,LDB2,AIFM1,TMEM257,SYNPR,RAB28,C4orf33,NIPBL,IQCK,FAM149A,AKAP6,LETMD1,SLC4A7,TBPL1,ANKRD44,RGS6,ARHGEF10,KIAA0040,CTH,ZFYVE16,LONRF1,SCRN1,ZEB2,DDX46,SV2B,WDR20,GNE,DNAJB6,DYRK1A,GOLT1B,EDN1,EDNRB,ANKRD46,RASGRP1,EGFR,EPHB1,KCNMB2,SPEG,RCSD1,F3,FAM198B,TOMM40L,FOXG1,CAP2,PCYOX1,SLC37A3,JKAMP,OGA,ARPP21,TUBGCP4,RNPS1,GPR75,TNRC6A,ZNF638,KCNMB4,GPM6A,GRIA2,GRM2,KAT7,ZBTB49,GYG1,AGBL5,DOCK7,IL6ST,LRRTM1,SLC35G1,KIT,LAMP2,ARHGAP12,MAP4,MBNL1,SYT9,MEIS1,MMP16,MRPL42,NRBP2,NF1,NINJ2,NODAL,LOC100128398,P2RX7,SNTG1,PCDH9,PDGFRA,PFKFB2,JAKMIP1,RC3H2,ING3,PPP1R1A,TATDN3,PKN2,RELN,PSMD13,ARID4A,ZYG11B,RFX2,RFX4,FBXW7,SPIN3,MIR124-2HG,FNDC3A,ST3GAL3,HECW1,KIF1B,MESP1,NKAIN2,ADHFE1,TBCEL,TCF12,SLC44A1,ERCC6L2,RUNDC3B,TRPC3,TTC3,TMEFF2,SLC17A7,PDSS2,FAM13C,ST7,FBXO36,ADAMTSL3,NETO2" MicroRNA "ATTCTTT,MIR-186:MSigDB" "ATTCTTT,MIR-186:MSigDB" MSigDB 2.73E-55 1.54E-51 9.31E-55 8.58E-54 94 253 "CLK4,ZNF608,OSBPL8,BCAR3,LRCH2,PARG,CNTNAP1,MIER1,BRINP2,DDX3Y,CALB1,CAST,LRBA,SEPT7,CDC42,QKI,ZNF385A,CNTNAP2,ZC3H11A,PLPPR4,SNAP91,G3BP2,GRIN3A,CPEB2,MBNL2,TMEM35A,PAN3,EPHB1,ACSL4,EFEMP1,DLC1,MEX3B,CELF1,STAG2,GABRA4,AHCYL1,FICD,ZHX1,BACH2,HNMT,NEGR1,INSM1,KCND2,KCNMA1,MAP2,MAP4,MBNL1,MITF,MYT1,NASP,IGSF11,P2RX7,GPR85,PFKFB4,PLP1,MAPKAP1,NXPH1,PPM1B,GTDC1,ZFHX4,SALL1,SMPD3,RASA3,SCAF8,CPEB3,FNDC3A,BTBD3,EPN2,TRIM67,CPEB4,MYT1L,SOX11,SP4,SRPK2,NECAB1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RBFOX2,DOK6,TRPC1,TRPS1,UBE3A,AMOT,CSDE1,PRDM10,SNX27,WNK3,PAK5,JPH3" MicroRNA hsa-miR-494-3p:TargetScan hsa-miR-494-3p TargetScan 2.81E-55 1.58E-51 9.58E-55 8.82E-54 123 446 "ADARB2,DSCAML1,KLRC4,ADCY5,ADCY6,PLEKHH1,PTCHD1,BEND6,MTUS1,GPR158,OSBPL6,PCDH10,APC,LRRC4C,IGDCC4,ARHGAP5,ARNTL,B3GALT2,BACH1,CAMK2D,CAST,CBS,CCNT1,DCLK1,DLGAP1,CNR1,FAM171B,CLOCK,RBM39,PLCXD3,PYGO1,CTIF,DNAL1,JAKMIP2,AK5,G3BP2,DPYSL2,ABI2,EIF5,EIF1,EN2,RCAN2,NSG2,CELF1,NRG3,GABRA5,ATP8A2,GHR,PPARGC1A,PRRC2B,GRIK2,GRIK3,GRM1,GUCY1A2,IRAK3,HAS2,ARHGAP19,NCKAP1L,ARHGAP36,ELOVL5,NEGR1,AGFG1,IGF1,IL6ST,KCNK1,KIF2A,KIF5C,KIT,LMO1,MAT2A,MDM4,LRP1B,NOVA1,OPCML,GPR137C,PCSK1,PDGFRA,PPP2R2B,PRKAB2,CEP41,MAPK10,DIRAS2,APTX,ANKHD1,PTPRB,RAB5B,RAD51D,RASGRF1,DBX2,MSANTD2,GTDC1,PBRM1,RPRD1A,RORB,CSRNP3,FBXO11,FHOD3,PEX26,CXXC4,MBD5,NMNAT2,ARHGAP26,NPAS3,PLCB1,CLASP1,PSD3,NSD1,ARHGEF12,ITGB3BP,LEFTY2,HHIP,ASXL3,LRTM2,CADM1,PITPNB,POLR3H,ANKS1B,LAMP5,DHX33,EVI5,HNRNPA3,NETO2,GAN" MicroRNA hsa-miR-4287:mirSVR_highEffct hsa-miR-4287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-55 1.97E-51 1.20E-54 1.10E-53 165 790 "ASIC1,TKTL1,NDRG3,KLHL32,GALNT13,PTCHD1,RTL9,TAOK1,SPOP,CDC42BPA,UPRT,GPAM,ALS2,BCAS1,NUMB,RIPK1,FGF17,CASTOR3,C5,CALB1,CAST,CCNH,MYOM2,CDH2,CDH8,LRRFIP1,LGI1,NDST3,CLCN3,FHL5,SLC25A27,AHCTF1,ZFP28,RBM39,RIMS2,CYBB,FRMPD4,LONRF1,DGKB,BRINP1,HEPH,ALKBH8,SMG7,FAM107B,EXOG,HS3ST2,DMTF1,PDCD6IP,ARRDC4,DNM1L,PHC2,KLHL5,AASS,SEZ6,EPHB1,SRRM1,WAC,SUCO,HPCAL4,SORBS1,ZNF512,GABBR1,ILDR2,AHCYL1,ARPP21,ZNF559,ARFIP1,CBX1,STMN2,DIDO1,SERP2,FAM19A2,MAP4K5,IRAK3,TOX2,ELOVL5,HMGB1,LRRCC1,INSM1,KLC1,TTYH2,MEIS1,MRPL42,BCO1,ZNF862,NDP,CNOT4,NTRK2,SNTG1,PDE1B,GNG2,RETREG1,ANKRD16,LRP12,SEPT4,SH3KBP1,POLR2F,POU3F2,PKIA,EPDR1,MAPK9,MAPK10,VPS13C,GDPD2,PTHLH,PTN,TRIM68,CCDC82,TMLHE,CARF,ROBO2,ATP8B4,MEG3,AP1AR,ATXN2,SCN2A,SCN7A,FAM19A1,SLC30A10,ASRGL1,ASAP3,MAGI3,FHOD3,CTXN2,SLA,RAB3GAP1,ARHGEF40,SLC9A5,SORCS3,SMARCE1,SON,MYT1L,ZSWIM8,UHRF1BP1L,ATP10B,ITPRID2,SSTR2,ZC4H2,LRRC4,RGL1,ADHFE1,FNDC9,SYP,SYPL1,FAM208A,TBCEL,TBX15,EHBP1,FRYL,CRB1,GPR161,CDH22,TIE1,NR2E1,TSN,UBE3A,PLEKHH2,STMN4,PRDM10,ADAMTS9,ITM2C,DOCK8,PAK5,GJC2,SLC4A10" MicroRNA hsa-let-7d:mirSVR_highEffct hsa-let-7d:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.03E-55 2.26E-51 1.37E-54 1.26E-53 163 773 "KLHL32,ERMN,ADRB2,RTL9,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,IGDCC4,ARHGDIA,DACT3,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,CH25H,AIFM1,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,SEC24C,OSBPL3,PDE4DIP,BOC,FRMPD4,DAPK1,B3GAT3,KLHL3,DLG2,DMD,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,EIF4G2,PLEKHO1,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,GATM,CYP46A1,CNTRL,ADAMTS8,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,RBPJ,IGSF1,ZNF678,DIPK1A,NME9,KCNC2,KCNJ11,KIF2A,MDM4,MEIS2,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,GPR88,OGG1,SERPINE2,A2ML1,XRN1,PMP2,PRRX1,PKIA,GDPD1,MASP1,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS12,RIC8B,LGI2,SETD5,EXD2,C12orf49,ROBO1,ATP8B4,LGR4,RTKN,MIR124-2HG,ATXN7,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,HECW1,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,TCEA1,ACSL6,TCF12,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,VSNL1,RICTOR,LYPD6,ZSCAN26,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-let-7g:mirSVR_highEffct hsa-let-7g:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.28E-55 2.41E-51 1.46E-54 1.34E-53 166 800 "NBAT1,KLHL32,BRAP,ADRB2,RTL9,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,AIFM1,CHN2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,OSBPL3,PDE4DIP,DAPK1,B3GAT3,KLHL3,DLG2,DMD,CPEB2,DPP6,SLC25A18,DTNA,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,PCDH11X,POLL,GNAS,CNTRL,ADAMTS8,PRDM5,BTN2A1,RASSF8,DDX19B,VSIG4,AGBL5,ZDHHC15,SOWAHA,NKD1,IGSF1,DIPK1A,NME9,KCNC2,KCNJ3,KCNJ11,KIF2A,MDM4,MEIS2,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,OGG1,PDE3B,SERPINE2,FAM218A,XRN1,PMP2,PRRX1,EPB41L4B,PKIA,GDPD1,MASP1,VPS13C,BDNF-AS,PTPRO,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS12,LGI2,SETD5,EXD2,C12orf49,ROBO1,ATP8B4,LGR4,CLIP1,MIR124-2HG,ATXN7,FNIP1,KIF27,FNDC3A,PAAF1,TET1,HECW1,KIF1B,CLASP2,ITPRID2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,UBE3A,ZNF781,RICTOR,PLPP4,LYPD6,ZSCAN26,SMARCAD1,SYNC,PRDM2,STOX2,WNK3,C12orf4,RTN4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-221:PITA hsa-miR-221:PITA_TOP PITA 6.13E-55 3.44E-51 2.08E-54 1.92E-53 97 273 "RALGAPA1,ARID1A,ADD3,AXIN2,PTCHD1,LRFN2,PITPNM2,APAF1,SHTN1,CAPRIN2,DDX3Y,ATP1A1,BCHE,KSR1,KMT2C,CNR1,SLC4A7,ZNF385A,RGS6,SEC24C,RIMS4,USP6NL,TOX,ZFYVE16,RIMS3,SPATA2,ZEB2,MYEF2,CDON,ARRDC4,DYRK1A,EMX2,ERBB4,SEC24B,SMC2,PPARGC1A,FERMT2,PRRC2B,GPM6A,GRB10,ADAMTS6,ZHX1,MIER3,AGFG1,C5orf24,INSM1,CLVS2,KCNK2,KIT,KLC1,STMN1,MARK1,MAT2A,ADAM11,MEIS1,NAP1L2,NEFH,NOVA1,KSR2,PCSK1,PIK3R1,PDZRN4,NXPH1,MED1,PPP2R5E,KANSL1,MAPK10,KHDRBS2,SLC25A36,SEMA6D,ATXN1,KIF16B,CPEB3,FNDC3A,WDR37,WDR47,CCDC88A,SNCB,TMCC1,SOX10,CDK19,POGZ,CAMTA1,CUX2,TRIM2,TCF12,DICER1,SIRT1,ZFPM2,TIAM1,TRPS1,SLC35A4,TUBA1A,SLC17A6,PAK5,HNRNPA3,SOCS4" MicroRNA hsa-miR-22:PITA hsa-miR-22:PITA_TOP PITA 6.22E-55 3.49E-51 2.11E-54 1.94E-53 94 255 "ACLY,EMILIN3,FMNL2,ADCY6,SORCS1,ADRA1B,ALCAM,PDZD4,DOC2A,DPP10,USP37,NCOA1,BACH1,WASF1,CABP7,KALRN,CAMK2G,VXN,BRSK2,FMNL3,ZMYM4,FOXN3,CHGA,RIMS4,PLCXD3,HDAC4,C2CD2L,ALKBH8,SMG7,SNAP91,SV2A,SEMA3D,EMX2,EPB41L2,ANKRD13B,ERBB4,ETV1,TESK2,FAM49B,FUT9,STAG2,MEGF11,MTHFD2,GATM,GPR162,TNRC6A,RAPGEF1,KAT7,SMAP1,C5orf24,INPP5B,MAT2A,SYT9,MEIS2,NEFM,NELL2,NOVA1,KCNK10,OLA1,SNRK,RAB5B,USP47,DPF2,RIC8B,FBXW7,ACER3,HUNK,NTNG1,CHD9,SLC1A3,BTBD3,SEPHS1,EPC1,WDTC1,KDM3A,GSE1,PRRC2C,ANKRD12,SATB2,SYNE1,ARHGEF12,SIRT1,ZNF106,TIAM1,ZFP91,HEY2,KAT6B,RBFOX2,PDSS1,KCNE5,TUB,AMOT,SNX27,KAT6A" MicroRNA hsa-miR-617:mirSVR_highEffct hsa-miR-617:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.50E-55 4.21E-51 2.55E-54 2.34E-53 148 647 "KCNH8,SYN3,ACTN2,PWWP2A,MTUS1,ZNF578,ABCD2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,DDO,SHTN1,ASPH,SYNJ2,USP6,CDC27,ZMYM4,NDST3,IGFBP7-AS1,BTF3L4,LETMD1,NECTIN3,CREM,AKAP12,HAPLN1,GDA,SOCS5,DCAF4,DOCK4,ARHGAP32,FRMPD4,KCTD8,ZEB2,G3BP2,DMD,DTNA,ABCC5,SEZ6,EPS8,NCALD,ADGRV1,CLVS1,CHST15,GORAB,FGF1,PRKAG2,FOXG1,C1orf61,FOXF2,SLC37A3,SORBS1,CHL1,ACSS1,TCERG1,RAB30,MAP7D2,CNTRL,PLCD4,GRM7,AP4S1,PSIP1,RNFT2,INSYN1,HNMT,HNRNPK,CFAP126,ZNF181,ZNF678,ARHGAP12,MAN2A2,AQP11,CD200,MYCN,SLCO1C1,OGG1,PCDH9,PDGFRA,GPR85,PURG,MAPK9,GON4L,PIGG,PTX3,FAM66C,RASGRF2,ZYG11B,RFX5,TTLL7,TMLHE,PNMA8A,CCDC102B,RPE,SNX22,EPHA10,ATAT1,AMER2,ITSN1,R3HDM2,SYBU,KANSL3,ARHGEF40,SLC11A1,SLC14A1,SPHKAP,SLN,MYH15,ANKRD36,SNRPN,PDZD2,SOX1,SOX5,FNBP1,UHRF1BP1L,ATP10B,CLSTN2,KANK1,SULF2,STXBP1,NECAB1,FGD4,VPS13A,KAZN,DDHD2,FBXW11,ANO4,ZEB1,DOCK9,USP32P1,TEX15,VWCE,SIRT1,C18orf54,AP4E1,ZNF106,AKTIP,SLC44A1,ZFP91,TRPC1,RUSC1,FRRS1L,MEAF6,ZNF19,LYPD6,SYNC,CA10,PCDH15,UBE3B,HNRNPA3,ADAMTSL3" MicroRNA hsa-miR-3115:mirSVR_highEffct hsa-miR-3115:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.19E-55 5.16E-51 3.12E-54 2.87E-53 145 623 "CLK4,C3orf14,BRAP,SNX30,HECW2,KLHL13,KCTD16,RTL9,LRRC7,SRPX,USP28,APBA2,ZSCAN18,CCAR2,ADAM23,TTLL9,SEC11C,DST,SCAPER,BSN,CA8,KALRN,ZMYM4,RCBTB2,CHN1,CASC2,B4GALT6,CLCN4,FAM19A5,SLC4A7,AHCTF1,GDA,ARHGEF10,VAC14-AS1,PDE4DIP,KIAA0408,HDAC9,KATNAL2,DGKB,DCC,KIAA0753,RHOBTB1,SNAP91,AK5,MED12,CPEB2,DMTF1,DPH1,PDCD6IP,GOLT1B,EDNRA,FCF1,RASGRP1,CALCRL,EFEMP1,SLC9B2,FGF14,CAP2,ST6GALNAC3,AP4B1,STAG2,GABRA1,CAB39,AHCYL1,KCNMB4,ZNF782,WDFY3-AS2,TDRKH,GPR17,KIF3A,TMEM25,GUCY1B1,HPS5,HLF,HNMT,NEGR1,CELF5,EID2B,FAM95B1,SLC6A17,LRRTM3,JAK2,KCND2,KIF5C,LIFR,LIMS1,NCOA7,CHIC1,CD200,NCAM1,NF1,OGDH,OPHN1,PCSK5,PDE1C,FAM218A,C19orf57,RASGEF1B,SNRK,MDGA2,RAP1GDS1,TRIM68,ERI2,RFX3,RFX5,ATXN2,SCN4B,LRRTM4,SLC30A10,ST3GAL3,DZIP1,FAM81A,DHX30,CCDC88A,RCOR3,TMCC1,UNC80,ZC3H13,KIF1B,DDN,SPART,C11orf87,EPB41L3,ST5,SEPT8,TCF4,GPRIN3,AP4E1,CSMD1,RASD2,PRMT8,RFTN2,USP1,ZNF709,ZIC3,ZNF142,SLC30A4,LINC00632,PLSCR4,RGS7BP,TRAM2-AS1,ZNF248,TIGD6,NHSL1,SENP7" MicroRNA hsa-miR-320e:mirSVR_highEffct hsa-miR-320e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.41E-54 7.91E-51 4.77E-54 4.40E-53 154 701 "NDRG3,SLITRK1,SORCS1,SLC44A5,AGT,PKP4,CDK13,STK33,ASPA,NCOA1,BACH1,ARHGEF7,IL33,CA8,CACNA1E,SLC25A14,CAST,SPAG9,CCNH,CDC25B,TIGD7,EPS15L1,PPT2,TJP2,LETMD1,TCEAL2,BAG4,CNRIP1,MFSD4A,CLOCK,AKAP12,GDA,SEC24C,PHF14,PNPLA8,CYBB,FRMPD4,GIT2,ARMCX2,ZEB2,MYEF2,RABGAP1L,DYNC1I1,MAMLD1,AASDH,USH1C,RASGRP1,FAM13A,SUGP2,MBNL2,PLEKHA1,CDKL3,ST3GAL6,POLR1B,FGF11,CAP2,POMT1,UFM1,PDLIM5,PRELID3A,AP4B1,NRG3,STAG2,TUBGCP4,ADAM28,GGTA1P,DBF4,MAP7D2,MCHR1,GRIA4,LINC01089,RNF165,PSIP1,ADAMTS6,ARHGAP19,TNFAIP8L3,KCNK2,LAMP2,PAXBP1,CLEC18A,MAT2A,AQP11,MBD1,MEIS2,KITLG,MXI1,NF1,NFE2L2,ALDH1L2,NINJ2,VWA2,HCN1,OGG1,CDK18,PDE3A,HERC2P3,GDAP1L1,NALCN,RETREG1,MTRF1L,PLXNB1,PRRX1,PPP2R2C,CEP41,CNTLN,OCIAD1,PEX5,RFX3,RFX4,SETD5,TMLHE,PNMA8A,RTKN,DGLUCY,SEMA6D,LRRTM4,FOXRED1,R3HDM2,CNKSR2,PAAF1,DHX30,SLC8A1,SLC14A1,SLC15A2,SORCS3,IFT122,ANKRD36,UNC80,SON,ERC1,BEX1,POGZ,COBL,ANKRD28,EXOC7,TCEA1,WASHC4,CLASP1,WDR7,PUM2,TMOD1,TPM1,TPM4,SMUG1,UBE2H,LMF1,KCNT2,CELF4,ANKS1B,CA10,NAV3,EPM2A,PHTF2,LAS1L" MicroRNA hsa-miR-24:mirSVR_highEffct hsa-miR-24:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.59E-54 8.91E-51 5.37E-54 4.95E-53 149 659 "TTYH1,ACADM,FMNL2,SLC12A5,TAOK1,LRRC7,PCDH10,ZNF687,OGT,PHF12,SUGT1P4-STRA6LP-CCDC180,AQP4,ATP2B1,SYNJ2,CACNA1E,THSD7A,CAMK2B,VXN,RHBDL1,SPAG9,USP2,AIFM1,MAGI1,CHM,CHN2,NDST3,IGLON5,ARMC8,ACBD5,CPS1,GDA,ABCG1,SNCAIP,NCAN,RIMS2,FGFR1OP2,PHF19,LONRF1,MATR3,SIRPA,KLHL3,PLPPR4,DNM2,GNE,FAM78B,ANKRD46,KLHL5,PHF20L1,LPAR6,TENM1,STARD3NL,PAN3,KCNMB2,CLVS1,SCML2,DLC1,STRADA,KIAA1109,FGF11,FHL1,STAMBP,ARFGAP2,SALL3,NEK6,GAP43,SESN1,GGT7,GPM6B,CNTRL,RAPGEF4,MFSD2A,USP54,INPP5B,ITPKB,KCNK2,KIF5A,SFXN5,NCOA7,SMAD9,MATN3,MEIS2,MT1M,RSPO2,MXI1,HNRNPM,NEFM,NELL2,NEUROD1,DNHD1,NUCB2,PAK3,PDGFRA,SERPINE2,EXOSC10,C19orf57,PPP2R5E,WDR25,PIGG,PTHLH,PXK,PTPRD,PTPRE,FAM120C,OXR1,HKR1,GTDC1,CARF,YY1AP1,NEK11,ADAL,LRRK2,ITSN1,SLC12A4,INTS9,SNRPN,EMC1,TAB2,ATP10B,POGZ,NEK4,SUPT5H,SYP,SEMA4A,ACSL6,WDR7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TIAM1,ERCC6L2,METTL3,TRPC3,PPIL6,ZKSCAN5,UGT8,BEST1,P2RY12,CLDND1,ZXDA,PCDH15,WNK3,PDSS2,SMIM8,VANGL2,SLC4A10" MicroRNA hsa-miR-486-3p:mirSVR_highEffct hsa-miR-486-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.93E-54 1.08E-50 6.54E-54 6.02E-53 153 694 "ABHD6,SLC12A5,CDC7,KIAA1211,ADRA1D,OLMALINC,SLC44A5,SNX32,SPOP,LTBP4,AMPD2,OGT,CNIH2,CNTNAP1,KCNAB2,PHYHD1,CACHD1,ARRB2,ASPH,ATP1A3,BTK,CACNA1G,CDK5R2,CACNA1B,NGB,VXN,INA,LRBA,CHN2,CASC2,JAM2,LSMEM2,KIAA1549L,DNAJB5,CNGA3,CNTFR,PNKD,CLIP3,CS,SEC24C,MICAL2,CST3,ECE2,HDAC9,DCAF8,SIRPA,PITPNC1,DDX46,G3BP2,CPEB2,BSCL2,EIF1,ANKRD13B,RAB9B,ERBB2,RTN3,ZIC4,ZSCAN30,TESK2,PPP1R1B,SPSB4,BAIAP2,FLNC,C2orf88,TMEM175,PDLIM5,ZNF512,MEGF11,GAB1,IGSF5,POLL,DIDO1,RFFL,ATE1,GRM2,LINC01551,NXPH3,HRH3,IDH3A,KCNA2,KCND3,KCNJ10,KHK,KIF5A,STXBP5,MAOB,MBD1,MDM4,MOV10,MSR1,MT3,TAGLN3,MXI1,RTL5,NEFH,SLCO1C1,NME4,DNHD1,OGG1,CDK18,PDCD2,PDE2A,SEMA5B,EPB41L4B,SH3KBP1,POU3F2,PKIA,PRKCG,APTX,SYTL2,PTPRN,RNF220,KIRREL1,MRAP2,RPE,BAALC,STK32B,COPZ1,ITSN1,FNDC3A,ST3GAL3,SMTN,LRRC55,YPEL4,SOX10,INKA2,ZSCAN29,ADHFE1,PHLDB1,SEPT3,NUDT10,PLCB1,DNMBP,TAL1,ANO4,TCF12,DOCK9,OBSL1,THRA,TIAM1,FNDC5,SSBP2,RPRM,PLPPR2,BEST1,SLC13A3,LYPD6,ZNF142,DNALI1,ADAMTS9,TMEM178A,HPS4,SLC17A7" MicroRNA hsa-miR-222:PITA hsa-miR-222:PITA_TOP PITA 2.04E-54 1.14E-50 6.89E-54 6.35E-53 96 270 "RALGAPA1,ARID1A,ADD3,AXIN2,PTCHD1,LRFN2,PITPNM2,APAF1,SHTN1,CAPRIN2,DDX3Y,ATP1A1,BCHE,KSR1,KMT2C,CNR1,SLC4A7,ZNF385A,RGS6,SEC24C,RIMS4,USP6NL,TOX,ZFYVE16,RIMS3,SPATA2,ZEB2,MYEF2,CDON,ARRDC4,DYRK1A,EMX2,ERBB4,SEC24B,SMC2,PPARGC1A,FERMT2,PRRC2B,GPM6A,GRB10,ADAMTS6,ZHX1,MIER3,AGFG1,C5orf24,INSM1,CLVS2,KCNK2,KIT,KLC1,STMN1,MARK1,MAT2A,ADAM11,MEIS1,NAP1L2,NEFH,NOVA1,KSR2,PCSK1,PIK3R1,PDZRN4,NXPH1,MED1,PPP2R5E,KANSL1,MAPK10,KHDRBS2,SEMA6D,ATXN1,KIF16B,CPEB3,FNDC3A,WDR37,WDR47,CCDC88A,SNCB,TMCC1,SOX10,CDK19,POGZ,CAMTA1,CUX2,TRIM2,TCF12,DICER1,SIRT1,ZFPM2,TIAM1,TRPS1,SLC35A4,TUBA1A,SLC17A6,PAK5,HNRNPA3,SOCS4" MicroRNA hsa-miR-421:PITA hsa-miR-421:PITA_TOP PITA 3.01E-54 1.69E-50 1.02E-53 9.36E-53 109 355 "ABAT,KLHL13,OSBPL8,ARHGAP5,SLC4A4,ATP2B1,SEC11C,CACNB4,RUNX1T1,CLDN10,LDB2,ZMYM4,CFL2,FOXN3,QKI,NIPBL,SLC4A7,BAG4,CRY2,CS,APPL1,PLCXD3,DOCK4,HDAC4,JAKMIP2,SNAP91,SPOCK3,DYNC1I1,ELAVL2,RCAN2,DNAJC27,EYA1,TESK2,FGF13,MEX3B,FOXO3,FAM49B,NCKAP1,PCDH17,PPARGC1A,SPIN1,GNAO1,GPD2,GRB10,FAM19A2,BACH2,IGF1,IPO5,ARHGAP12,PACRG,SMAD1,MARK1,MEF2C,MEIS2,MITF,NCAM1,NFYA,CNOT4,NPTX1,CLDN11,PDE4B,PDGFRA,SERPINE2,XRN1,PMP22,STRN3,NXPH1,POU3F4,PPP2R5E,KANSL1,BCAS3,PTPRB,USP47,RDX,RFX3,NUDT11,RORB,ATXN1,ELMOD1,SOX6,PPM1E,PPP4R3A,EPN2,SLC8A2,SEPHS1,RAB3GAP1,KBTBD4,CPEB4,SNAP25,TTBK2,ARHGEF9,ANKRD12,CAMTA1,CAMSAP2,RALYL,FBXL16,DAAM2,TSN,TUBB2A,FLRT2,SF1,ZIC1,TMEM237,POLR3H,WNK1,CADM2,SCG2,KAT6A,RNF146" MicroRNA hsa-miR-450a:mirSVR_lowEffct hsa-miR-450a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 3.21E-54 1.80E-50 1.08E-53 9.99E-53 116 404 "ADD2,KIDINS220,AP2A2,GPR158,C1QTNF3,ANK3,SUGT1P4-STRA6LP-CCDC180,USP37,AQP4,GPR146,CACNA1B,LGI1,LRWD1,NRXN1,ARHGEF6,ABI3BP,ZFP28,SLC32A1,OSBPL3,IPCEF1,PHF14,DOCK4,GPRASP1,TOX,TBC1D5,MATR3,INTS1,SPOCK3,TMCC2,DLG2,GRIN3A,RAB39B,DMPK,NR1D2,DPH1,PDCD6IP,OPTN,MBNL2,PLEKHA1,ELAVL4,LRRC17,ENPP6,SCML2,MEX3B,IP6K2,PSD2,SGIP1,PDLIM5,PRELID3A,GABRA3,HBS1L,NCKAP1,ERAP1,DISC1,ATP8A2,ZNF276,GNAS,STMN2,GRIA2,GRM8,CIT,MAP4K5,ATOH8,KIAA1755,KCNK2,IPO5,GPR155,MEIS2,AFF1,SAMD5,SESN3,ADAM22,NEK1,OPHN1,PBX1,CDK14,SLC25A23,EXOSC10,ING3,TATDN3,RASGEF1B,TMEM260,PTPRZ1,MARCH1,PID1,IQSEC3,ZYG11B,NUDT11,GSTCD,ZC3H14,MEG3,ST6GALNAC6,ATXN2,ITSN1,FNDC3A,SLC1A6,KANSL3,SLC22A4,ANKFN1,BDP1,ATP10B,COLGALT2,CEP68,HIF3A,AP4E1,TJP1,C9orf85,FAM155A,UBTF,VLDLR,RBFOX3,ZIC3,ZBTB38,SLC17A6,FZD3,ACTR3B" MicroRNA hsa-miR-1185:mirSVR_highEffct hsa-miR-1185:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.27E-54 2.40E-50 1.44E-53 1.33E-52 153 698 "TTYH1,SDE2,NBAT1,ACTN2,KDM5D,CSMD3,NDRG3,SLC44A5,SMIM17,ASPH,ATP1B3,STX16,ATP2B1,CFLAR,SYNJ1,CA8,CACNA1D,CACNB2,CANX,RUNX1T1,KRIT1,L3MBTL4,CDO1,UBE2L6,RAB3C,ABCG2,BTF3L4,MFSD4A,HINFP,SNCAIP,PABPC5,C8orf34,HEPH,CEP170,MAGI2,TMCC2,DPP6,DNM1L,GOLT1B,EDNRA,ANKRD46,SEMA3D,TMTC1,YAF2,PHF20L1,SUGP2,PPP1R1B,GORAB,FGF13,FGF14,FOXM1,AKAP3,ATP6V1H,ZNF605,CGREF1,B3GAT1,TBR1,ZNF512,CHL1,GABRB3,TRAF3IP2,DISC1,KIAA1841,GGT5,CRCP,RAB30,LUZP2,ADGRA3,LPAR4,ADAMTS6,HPSE2,HTR5A,MSL1,LRRCC1,HES5,IL6ST,SLC35G1,OLFM3,KCNC2,STXBP5,FGFBP3,MAOB,MAT2A,MATN2,SHC3,BLOC1S2,CTNNA3,MYO7A,FXYD6,P2RY13,NCAM2,NF1,ETFRF1,PCDH18,PMP2,STRN3,RC3H2,ING3,APTX,SYTL2,GON4L,C1orf109,CEP97,OXR1,RGS4,LGI2,ZNF532,TMLHE,ZNF568,TRAPPC13,LRFN5,CASC3,MRAS,SH3GL2,SYBU,NLGN1,SLA,SLC12A2,CPEB4,MBD5,MYO16,ENKUR,CLASP2,SS18,APOM,SEPT8,STXBP1,PRRC2C,SYT1,CAMTA1,TCF12,WDR7,ARHGAP9,DICER1,HEY2,ZNF384,TRPS1,TSN,AMOT,PITPNB,CFAP298,PLPP4,UPF3A,PRDM2,LINC02210,RNF103,HPS4,WNK3,PARP11,AMN1,ST7,PHTF2,JPH3" MicroRNA hsa-miR-608:mirSVR_highEffct hsa-miR-608:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.42E-54 2.48E-50 1.49E-53 1.38E-52 149 664 "VWA5B2,CPNE2,NDRG3,DSCAML1,ADGRF5,SPOP,MARCH4,KIF6,ZFAT,OGT,PHF12,SEMA4G,ARRB1,ASCL1,NCOA1,ATP1A1,CARMIL3,AZGP1,MPDZ,NRP2,CACNA1B,CALB2,CBLN1,LDB2,INA,CD86,ENTPD2,ZMYM4,DLGAP1,LSMEM2,EPS15L1,TPP1,FADS2,DNAJB5,IGLON5,WHRN,CLIP3,LRRC3B,NRSN1,CYBB,HDAC9,GAPVD1,RIPOR2,DGKG,DBN1,PITPNC1,COPS7A,RAB39B,DYRK1A,EBF1,EDNRA,EGFR,SORBS3,ELN,NRN1,F5,ZSCAN30,SYT3,COQ5,ZCCHC17,HVCN1,CELF1,B3GAT1,GABBR1,TRAF3IP2,ZMYND11,B4GALNT1,IQGAP2,ERAP1,SEPT9,GPR162,TTBK1,GLDC,GLI2,GNAS,PSRC1,PRUNE2,DIDO1,PLCD4,ZNF496,FAM107A,HNRNPK,SMAP1,LRRTM1,KCND1,KCNH2,KCNJ3,KCNMA1,KCNN1,TM6SF1,PPM1L,MOV10,ERICH3,GIT1,NPPA,NRGN,PFKFB3,EPN1,PNMA3,PMP2,KANSL1,MAPK3,SLC26A11,KLK6,PSD,PXK,CCDC40,MSANTD2,GTDC1,KIRREL1,NCBP3,TRIM46,ITSN1,PPP4R3A,SLC8A3,SLC11A1,ATF7IP,SNAP25,SNCB,MBD5,PALLD,PBLD,DIP2A,NSFL1C,VAMP1,SLC37A2,SYT5,SYNE1,PCDHB9,NSD1,HIF3A,MTMR14,TMOD1,RIMBP2,C5orf64,SEZ6L,TPM2,ZNF384,PRMT8,ZMYND8,SLC13A3,LGI4,TMEM198,SCG2,SIGLEC10,PCDH15,NAV2,RTN4,PRRT4" MicroRNA hsa-miR-1277-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.68E-54 3.75E-50 2.26E-53 2.08E-52 144 624 "ABCF1,FMNL2,ADD2,GRAMD1B,NLGN4X,ZNF608,TAOK1,FAM135A,MARCH3,NUMB,FUBP1,CA8,CA12,THSD7A,CANX,RUNX1T1,CFL2,SLC24A2,C4orf33,QKI,SLC25A27,BTF3L4,TBPL1,ACBD5,ANKRD44,UBXN2A,PUM1,USP6NL,DOCK4,MYADM,DGKG,DAPK1,PITPNC1,SPATA2,G3BP2,CDON,CPEB2,YAF2,ABI2,GOLGA7,CERCAM,RCAN2,EPHA5,FER,POLR1B,TRMO,ZBED3,NPTN,MSANTD4,MPP6,GCK,MMADHC,PPARGC1A,COPS8,TPPP,GRID1,GRIK3,NR3C1,BVES,INSYN1,BACH2,USP51,NEGR1,HSP90AA1,IGF1,IGFBP1,ZIC5,SCIN,IL6ST,ZNF678,KCNB1,CLVS2,KCNJ3,KLHL23,KCNK1,KCNN3,L1CAM,SMAD9,MMP16,CCDC80,MYBPC1,NEXMIF,NCAM2,NTRK3,PIK3R1,XRN1,PURG,PSAT1,PRRX1,PPP1R1A,PPP2R5C,PPP2R5E,EPDR1,MAPK8,PROX1,SNRK,RAB5B,CEP97,PRIMA1,CARF,ACER3,AP1AR,CSRNP3,ATXN1,FAM19A1,WDTC1,SOX5,ZHX3,ERC1,AJAP1,NECAB1,PRRC2C,SYP,SYPL1,DDHD2,TMEM178B,TRIM2,DOCK9,AHCYL2,SIK3,ZMAT3,HHIP,CSMD1,RGMB,NR2C2,TRPS1,CADM1,OSBP2,MEAF6,CCDC14,KCNK12,ZBTB16,SMARCAD1,SLC30A4,MAP3K12,ZXDA,CADM2,LRP8,SLC38A1,EVI5,STOX2,FAM182B,KAT6A,SSPN" MicroRNA hsa-miR-1293:mirSVR_highEffct hsa-miR-1293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.67E-54 4.87E-50 2.92E-53 2.69E-52 132 528 "SERPINA3,SORCS1,OLMALINC,SLC24A4,RTL9,ZFAT,ANK3,LGR5,ARRB1,N4BP2L1,TTLL9,DST,BTK,CACNA1B,CACNA1D,VSTM2A,INA,REPS2,CDC42,SRSF11,NRXN3,SRP14-AS1,CNR1,SLC4A7,CCDC144A,KIAA0586,DGKG,DCC,PITPNC1,GSDME,DLG2,TOM1,SGK2,MBNL2,ABI2,VPS13B,SEZ6,SRRM1,NRN1,F5,ZSCAN30,KAT8,POLR1B,WDR83,SMC2,NSG1,HRASLS5,GABRB1,DISC1,KIAA1841,TUBGCP4,TUBA8,USP19,GLUL,GNAS,PRUNE2,ATE1,CELF3,MAEL,PLD5,KCNJ10,LIMS1,TM6SF1,MDM4,MEIS1,MEIS2,GIT1,MRPL42,NELL1,NEUROD2,NOS1,CNOT4,SNTG1,NLGN3,PLCL1,PRIMPOL,SH3KBP1,RANBP3L,SLC26A11,SLC22A23,RAB3A,SLC25A48,RBBP6,ZYG11B,GTDC1,ZFHX4,RERGL,PNMA8A,GSTCD,ROBO1,ROBO2,MRAP2,ABCA11P,SEMA6D,ITSN1,FERMT1,SLITRK3,ZNF365,RPH3A,SLC1A7,ATF7IP,SMARCD3,SNRPN,PALLD,PDZRN3,WDTC1,SOX5,TAB2,POGZ,ZSCAN29,VAMP1,ARHGEF9,COBL,SYT4,MLST8,TBX15,DMXL2,TCF7,FAM200B,FAM124A,C5orf64,ELP5,TRO,MGAT5B,NPDC1,CELF4,ZNF225,DNALI1,PDSS2,FBXO36,IFT88,GAN" MicroRNA hsa-miR-1207-5p:mirSVR_highEffct hsa-miR-1207-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.21E-54 5.17E-50 3.10E-53 2.86E-52 163 790 "ASPHD1,ADD2,SORCS1,ZNF608,SNX32,KIAA1324,ALCAM,MRTFA,BEGAIN,AMPD2,APC,CHRD,ADAM15,RGS11,CDK5R1,CDK5R2,CACNA2D1,SLC25A14,NFS1,INA,LGI1,CHRM1,PLEKHB1,DLGAP3,ZFYVE9,COL9A2,AKAP5,ACBD5,ZFP28,PNKD,SEC31B,SNCAIP,ARHGEF10,SUSD5,NRSN1,RIMS2,DCAF4,BOC,GIT2,FBXO25,RHOBTB1,SV2A,HS3ST2,DNM2,CPEB2,SLC25A18,DTNB,SGK2,KLHL5,CACNG7,CELSR3,PHF20L1,SUGP2,APH1A,SORBS3,C3orf18,EFS,TESK2,PPP1R1B,CAP2,IP6K2,AGAP3,FOXM1,FLT1,SGIP1,ZCCHC17,CELF1,ABLIM2,MEGF10,B4GALNT1,NCKAP1,ERAP1,C15orf41,CYP46A1,MSL3,CBX1,OS9,GOLGB1,STMN2,SPACA9,COQ10A,SLC2A6,SHISA6,NKD1,DISP2,IL6ST,INSM1,PAXBP1,VWA5A,NCOA7,LSS,ZFYVE27,MARK1,KCTD6,MPP2,RTL5,NELL1,NME4,NOVA1,NTRK3,DDR2,OLR1,PCSK5,GPR173,CCSER2,NLE1,MBOAT7,EPB41L4B,SH3KBP1,MED1,VSTM2L,CEP41,MASP1,BCAS3,ZNF844,RAP1GAP,TRIM68,GTDC1,SLC25A36,CARF,FBXW7,CASC3,NLGN4Y,ITSN1,CCDC92,SYBU,SLC1A7,DHX30,FAM214B,SLC6A9,ARHGEF40,SLC9A5,KDM4B,ZC4H2,CEP68,ADHFE1,FGD4,ZC3H4,MLST8,CLASP1,AZIN2,OBSL1,FRYL,RNF216P1,CRB1,SEZ6L,TPM1,NPL,TPM2,RGMB,ZMYND8,CADM1,FLRT1,PLPPR2,WIPF1,XRCC4,ZIC3,TMEM198,LMAN2L,ADAMTS9,NAV3,SLC17A7,GAN" MicroRNA hsa-miR-217:PITA hsa-miR-217:PITA_TOP PITA 1.13E-53 6.35E-50 3.81E-53 3.51E-52 103 319 "KCNH8,CSMD3,INTS2,SEMA6A,ANK3,USP37,SLC4A4,ADGRB3,CDK5R1,LDLRAD4,SEPT7,DLGAP2,CHN2,KMT2C,QKI,NIPBL,CNR1,COL4A5,RBM39,CREB5,ST18,KIAA0408,DOCK4,YTHDC1,MYEF2,CPEB2,RCAN1,DYRK1A,EDIL3,YAF2,PAN3,EPHB1,ACSL4,ATP8A1,FGF11,FOXO3,AFF2,TACC2,FAM49B,DACH2,SARAF,STAG2,PCDH17,GLS,GPM6A,GRIK2,KLF12,MIER3,C5orf24,DOCK7,LRRTM3,STXBP5,ARHGAP12,NCOA7,MXI1,NAP1L2,ZC3H12B,NEUROD1,NF1,NFIA,NNAT,NOVA1,CNTN3,PCMT1,ANLN,GDPD1,FIGN,RTN1,SATB1,ELMOD1,SFPQ,HSPA4L,PPM1E,FBXO11,SLITRK3,SLC1A2,WDR47,GKAP1,SOX11,EPB41L3,LARP4,STX1A,ZC3H4,SYN2,TACC1,ADGRL3,FBXW11,ZEB1,RPGRIP1L,SIRT1,TLR4,TPD52L2,TBC1D15,VSNL1,ZNF711,MICU3,REEP1,STOX2,TMEM178A,HNRNPA3,CERS6,FXR1,SENP7" MicroRNA hsa-miR-488:PITA hsa-miR-488:PITA_TOP PITA 1.30E-53 7.32E-50 4.39E-53 4.04E-52 104 326 "ARID1A,CSMD3,FMNL2,ADRB2,KLHL13,PCDH19,ZNF687,ANK3,ATP2B1,SYNJ1,BSN,CALM1,PTBP2,REPS2,CDC42,LGI1,FOXN3,CHN2,NRXN3,SLC4A7,TENM4,CEP170,KLHL3,DLG2,SLC12A6,PHC2,EFNB3,TENM1,ELAVL2,RAB9B,FGFR3,FAM49B,NPTN,KHDRBS3,TMEM151A,STAG2,GABRB3,CPLX2,PRRC2B,GRIN2D,PTPRT,CELF3,WIF1,HMGB1,IGF1,ZIC5,PLD5,MAP2,MAT2A,MBNL1,RSPO2,NEXMIF,NFIA,OCRL,PDE4B,PFKFB3,PIK3R1,XRN1,PCDH18,LRP12,PKIA,PKN2,GRAMD1C,QRICH1,TMEM260,PEX5,SH3TC2,KHDRBS2,FIGN,AP1AR,ATXN1,SHC4,CCDC88A,SNCA,FAM126B,MYT1L,TEX2,EPB41L3,NKAIN2,ERBIN,SYT1,POPDC3,CAMTA1,CAMSAP2,DICER1,SLC44A1,ZFP91,CSMD1,RBFOX2,AMACR,HEPACAM,UBC,CADM1,PLEKHH2,GDPD5,PRDM10,SLC17A7,SNX27,KCNAB1,WNK3,KAT6A,CERS6,NETO2,ST8SIA2" MicroRNA hsa-miR-598:mirSVR_lowEffct hsa-miR-598:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.33E-53 7.49E-50 4.48E-53 4.13E-52 122 453 "SYS1,HFM1,SEMA6A,SUGT1P4-STRA6LP-CCDC180,PPFIA3,MIER1,MARCH3,ASPH,RASL11B,SLC2A11,B3GALT2,DPY19L3,TTLL9,SNAI3-AS1,JAZF1,CAMK2A,RAB33A,FAM149A,ABI3BP,CHD1L,CHD5,PDE4DIP,CTNND2,DOCK4,ZNF804A,MFAP3L,COPS7A,CEP170,NTM,WDR20,DLG2,NR1D2,DOCK2,DTNA,FAM135B,RASGRP1,EIF5,ELAVL2,TUBD1,LRRC17,RABEPK,MRPL37,ETV1,POLK,CAP2,IP6K2,EVL,SLC37A3,PDLIM5,ERAP1,RAB30,STARD3,GNAS,PRRC2B,GRIA4,GRM7,BTN2A1,GUCY1A1,ATOH8,MIER3,ICA1,LRRCC1,ITGAM,KCNA1,MAP2,MARK3,MEIS2,MEST,XRRA1,MOBP,ADAM22,MYCN,NEUROD2,CNOT4,PDGFRA,POLR2F,PPP2R5E,PPP3CB,RASGEF1B,PKIA,WBP1L,PLPPR1,STK32A,RAD51D,ZFHX4,CARF,ELP2,ADAL,ACER3,HSD11B1L,TRAPPC13,SCP2,SEC14L1,NLGN4Y,RADIL,SLC12A2,SLC12A4,CABCOCO1,FNBP1,KDM3A,KDM4C,CDK19,RAP1GAP2,SYN1,KLHL4,ANO4,WDR7,AZIN2,PMS2CL,TMEM9,ZFP91,TRPC3,UBE2H,VLDLR,GUSBP1,ZIC3,ZNF138,INTS3,ADAMTS9,SIGLEC10,PDSS2,JMJD1C" MicroRNA hsa-miR-650:mirSVR_highEffct hsa-miR-650:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.35E-53 7.58E-50 4.54E-53 4.18E-52 156 730 "XKR4,ADCY2,ADORA2A,KIAA1324,PCDH10,FAM135A,TNRC6C,ARHGDIA,NCOA1,CHID1,EIF4G3,KIF1A,BCL2L2,SYNJ1,CDK5R2,CACNA1E,RUNX1T1,USP2,P2RX6,DLGAP1,CFL2,CHN2,CPNE6,NMT2,FBXO7,QKI,SUMF2,LETMD1,GAL3ST1,FAM171B,ANKRD44,CS,MICAL2,CSNK1G3,VCAN,DZIP3,CX3CR1,ARHGAP32,GAPVD1,DGKB,PABPC5,ZC3H11A,SV2A,EXOG,RPS6KL1,CASP8AP2,DPP6,ACOT8,DTNA,E2F6,EDN1,PHF20L1,EBI3,ING4,SRRM1,SIRPB1,FAM198B,DLC1,FCGR1A,SUCO,PSD2,HRASLS5,FAM120B,B4GALNT1,JPH4,INPP5K,GK,GLS,GNAS,PCLO,GRIN2D,FAM19A2,TOX2,ICA1,ZIC5,IGSF1,KCND2,SYT9,MITF,CD200,MXI1,MYO9A,SFR1,NF1,NTRK3,NUMA1,PCSK5,CDK18,PDE1B,NALCN,CCSER2,PLCL1,PMP22,GRAMD1C,HYDIN,DCHS2,RELN,LRRC49,SIDT1,PLPPR1,PTPRE,ZNF493,RASGRF2,SLC6A15,ZYG11B,RGS7,NUDT11,C12orf49,ARMC5,ROBO1,TMEM100,WLS,KCNIP1,RYR3,AP1AR,SCP2,DZIP1,RAB3GAP1,SLC8A3,IFT122,SOX10,ZC3H13,DBNDD2,SRPK2,ZSCAN29,FGD4,ABCC8,VAMP1,NUDT10,DNAJC9,TBCEL,FBXW11,USP32P1,DICER1-AS1,AP4E1,SLC44A1,TIAM1,HEY1,R3HDM1,ZNF346,RUNDC3B,TRPC3,KCNE5,HEPACAM,MTCH1,ZNF177,WNK1,PRDM2,ADAMTS9,ST7,PAK5,CASC15,JMJD1C,NLRP3,VANGL2,SLC4A10" MicroRNA hsa-miR-191*:mirSVR_lowEffct hsa-miR-191*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.41E-53 7.92E-50 4.74E-53 4.36E-52 137 570 "KCNH8,ABHD6,ACTN2,XKR4,ADD1,ADORA2A,OLMALINC,AGT,OSBPL1A,CC2D2A,ANK1,GPAM,PPFIA3,ZFYVE28,MARK4,NCOA1,SLC4A4,DPY19L3,BCHE,NRP2,CACNA1I,MYRF,CA12,VXN,RUNX1T1,CDH18,LGI1,CACNA2D2,CHRNA4,NRXN3,TPP1,CNN3,CNTN1,AKAP5,MYRIP,CNRIP1,SNCAIP,TENM4,PDE4DIP,TOX,LIN54,SPOCK2,ZEB2,COPS7A,SRGAP3,DLG3,RPS6KL1,DPH1,FAM57B,PDCD6IP,DUSP9,PHC2,SGK2,HEYL,ABI2,ELN,MFSD10,ANKMY1,ECSIT,TUBB4A,FCGR3A,FCGRT,FGF1,AGAP3,STAG2,CHL1,ARPP21,TUBGCP4,PPARGC1A,GNAL,GOLGB1,PRRC2B,GRIA4,CACFD1,GRM2,PACSIN2,HSD17B1,SHISA6,FAM95B1,INPP5B,KCNMA1,ASPRV1,MEIS1,PTOV1,MTR,NCAM1,OPRL1,SEMA5B,SCHIP1,MINDY2,PRKCB,PRKCG,RELN,NDUFS7,PTPRN2,RAD51D,MYH14,KLHDC8A,CCDC25,ATXN2,SCN7A,FHOD3,ST3GAL3,ABLIM3,URGCP,TMEM132D,SMARCA4,UNC80,WDTC1,ZSWIM8,PEG10,SPTB,C11orf87,EPB41L3,ADHFE1,FGD4,VPS13A,FNDC9,SYT1,TACR1,VWA3A,TCF7L2,WDR7,RNF216P1,DICER1-AS1,ZMAT3,ACTR6,LRRC8A,TMOD1,TRO,TTTY15,PITPNB,NSD2,NPDC1,PRDM2,CASC15,JPH3" MicroRNA hsa-miR-3201:mirSVR_highEffct hsa-miR-3201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.66E-53 9.34E-50 5.58E-53 5.14E-52 139 587 "NBAT1,FMNL2,SLITRK1,ZNF608,KCTD16,NME5,OSBPL6,TAOK1,LRRC7,TMEFF1,CADPS,N4BP2L1,ADAM23,SYNJ1,CACNA1D,CALB1,KCNAB3,ZMYM4,LGI1,CHM,SRP14-AS1,SLC4A8,ST18,ZSCAN23,DOCK4,KATNAL2,DCAF8,IST1,MAGI2,NTM,RABGAP1L,RAB39B,GOLT1B,EDIL3,EDN1,FAM135B,EFNB3,PHF20L1,TENM1,ELAVL2,STARD3NL,DCTN4,OLIG2,LRRC17,CDKL3,F5,ABCA8,ACSL4,EFEMP1,GORAB,SCARA3,C1orf61,PCYOX1,COQ5,SMC2,UFM1,CELF1,NRG3,DKK3,HRASLS5,AHCYL1,IQGAP2,WASF3,KIAA1841,ADAM28,MALT1,GPR37,DIDO1,GSN,ARHGAP19,HMGB1,OPALIN,IRF8,ZIC5,KCNA4,KCNC2,KCNK2,STXBP5,NCOA7,MAT2A,MEIS1,MITF,CPNE9,BLOC1S2,NRBP2,NCAM2,NF1,OCRL,OLR1,LOC100128398,PCDH9,SNX10,FTO,HMGCLL1,PPP3CB,KANSL1,GRAMD1C,CNTLN,PTHLH,MARCH1,RAB5B,SUSD4,RAP1GDS1,RBBP6,RGS12,RAVER2,ROBO2,CCDC102B,PRR5L,LRRTM4,SLITRK3,ST3GAL3,SEPHS1,SLC8A3,INAVA,LIMCH1,RIMS1,UNC80,RBM26,C11orf87,ST5,STAU1,SEPT8,DIP2A,VWA3A,ATMIN,EHBP1,WDR7,PRMT8,AMACR,STXBP4,TMEFF2,CADM1,GUSBP1,ZIC3,EPM2A,SLC4A10,GAN,JPH3" MicroRNA hsa-miR-197:mirSVR_highEffct hsa-miR-197:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.83E-53 1.03E-49 6.13E-53 5.65E-52 147 654 "RBM10,NBAT1,CC2D2A,TAOK1,MRTFA,PKP4,PHYHD1,SPTBN4,PLA2G4C,CAPRIN2,SLC4A4,BACH1,ZNF599,CAST,CBLN1,CBR1,INA,ARHGAP33,L3MBTL4,RAB28,ARMC8,SLC4A8,HS3ST5,SLC32A1,TRIM69,SNCAIP,VAC14-AS1,PDE4DIP,FAM169A,PITPNM3,CTNND1,CX3CR1,HDAC9,FGFR1OP2,TCAF1,GIT2,C8orf34,GSDME,DLX1,GRIN3A,DNM1,DPH1,EBF1,EDNRA,EDNRB,MRNIP,EPB41,KCNMB2,CEP85L,EYA1,TAOK3,FCGR1A,CEP78,SLC37A3,ZCCHC17,STAG2,ATP8A2,WDFY3-AS2,GOLGB1,TDRKH,CCDC184,CECR2,GRIA2,PLCD4,GRIN1,CLASRP,SMAP1,ZNF181,IGFBP1,ZIC5,JAK2,KCND2,KCNN2,KLRC2,STXBP5,PPM1L,MTTP,NCAM1,NELL1,NF1,NKX2-2,OPHN1,OXTR,PBX1,PDE3B,PDGFRA,GPR85,OLA1,PLCL1,ING3,SEPT4,POU3F2,PPM1B,CCDC144B,PRKCZ,EPDR1,GRAMD1C,GON4L,TMEM145,RAB5B,SUSD4,RDX,RGR,ARHGEF10L,RPRD1A,C12orf49,ELP2,CCDC102B,FBXW7,SCN7A,SCN8A,SUPT20H,ITSN1,SH3GL3,NLGN1,ST3GAL3,SLC2A5,CCDC88A,SLC20A2,NAXD,RIMS1,UHRF1BP1L,KDM4C,IDI2-AS1,ZNF302,SST,SS18,DIP2A,SYT4,TAL1,EHBP1,SATB2,ARHGEF12,ITGB3BP,MTMR14,PRRT1,PRMT8,UBE3A,PITPNB,MEAF6,RICTOR,ZIC3,MDH1B,PDSS2,FZD3,SNX14,PIANP" MicroRNA hsa-let-7b:mirSVR_highEffct hsa-let-7b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.25E-53 1.26E-49 7.54E-53 6.95E-52 161 777 "ARID1A,KLHL32,ERMN,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARRB2,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,CH25H,AIFM1,TAOK2,NDST3,PPT2,COG1,QKI,MAP4K4,NIPBL,IQCK,SLC25A27,AHCTF1,IGDCC3,MFSD4A,MICAL2,OSBPL3,FRMPD4,DAPK1,B3GAT3,DLG2,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,RACK1,PPP1R1B,GORAB,FGF11,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,GABBR1,GABRA2,GALNT15,GAD1,FAM120B,GALC,C15orf41,DNER,GATM,CYP46A1,POLL,GNAS,CNTRL,ADAMTS8,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,NKD1,RBPJ,IGSF1,DIPK1A,NME9,KCNC2,KCNJ11,MDM4,MEIS2,MOBP,SESN3,RSPO2,NAP1L1,CNOT4,NOVA1,GPR88,OGG1,SNTG1,XRN1,PRRX1,EPB41L4B,PKIA,GDPD1,MASP1,PTK2,PTPRO,RAB3A,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS3,RGS12,RIC8B,LGI2,SETD5,C12orf49,ROBO1,ATP8B4,ACER3,LGR4,MIR124-2HG,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,RUFY2,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,TCEA1,ACSL6,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,BEST1,RICTOR,PLPP4,LYPD6,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-1201:mirSVR_highEffct hsa-miR-1201:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-53 1.28E-49 7.63E-53 7.02E-52 135 556 "SDE2,ADAR,ALS2,LGR5,ARSF,LINC00173,CDK13,MARK4,NCOA1,ATP2B3,RGS9,PTBP2,CAST,MAP7,CCKBR,CD81,DLGAP1,CHM,SYNPR,CNOT8,TPP1,LETMD1,CREM,HAPLN1,HINFP,NCOR1,CS,ARHGEF10,DOCK4,GAPVD1,FRMPD4,KIAA0586,DGKB,SV2B,AK5,NYAP1,DMTF1,DPP6,PDCD6IP,DTNA,ABCC9,ANKRD46,RASGRP1,ELAVL2,GPHN,CEP85L,EXTL2,TAOK3,UFM1,NPTN,CGREF1,OGA,CAB39,ARPP21,SALL3,DISC1,NEU3,HPGDS,PCDH11X,ZNF638,FERMT2,EML4,GRIN2C,LINC01551,RABL2A,MAEL,IGSF21,TNFAIP8L3,IRF8,RBPJ,KCNA4,CLVS2,LIMS1,MBNL1,SYT9,MEIS1,POC1B,MMP16,MYO6,NFE2L2,DNHD1,NRCAM,NUMA1,OPA1,PCSK5,PDGFRA,GPR85,ZNF655,XRN1,PURG,TRHDE,SCHIP1,RETREG2,APTX,SIDT1,RBBP6,PBRM1,CCDC102B,PRR5L,RMI1,SEMA6D,CSRNP3,TNFRSF19,NLGN4Y,ST6GAL1,ANKRD6,SLC8A3,CPEB4,DOK5,CLUAP1,TEX2,POGZ,ELOVL4,TTBK2,PRRC2C,TCF7,WASHC4,PCDHB4,ZFPM2,ITGB3BP,AP4E1,ZNF384,AMACR,TTTY15,SGK3,ZNF45,FMN2,PLPPR5,FAM47E,FBXO36,CASC15,TRAM2-AS1,KLHDC1,DPF3,ST8SIA2" MicroRNA hsa-miR-1324:PITA hsa-miR-1324:PITA_TOP PITA 2.53E-53 1.42E-49 8.48E-53 7.81E-52 104 328 "ASIC1,ADCY6,NLGN4X,TAOK1,SEMA6A,SPOP,ALCAM,ARHGAP20,APBB1,APBB2,ATP2B2,CDK5R2,CALB1,CAMK2A,FMNL3,MAGI1,FOXN3,TAOK2,AKAP5,ARHGEF10,UBXN2A,ST18,SNPH,HDAC4,SIRPA,YTHDC1,CEP170,SNAP91,DLX1,CPEB2,DSCAM,FAM135B,HIPK3,GPHN,EPS8,SPEG,WAC,ST3GAL6,SUCO,AFF2,SYT3,TMEM107,CSPG5,BRPF3,FERMT2,RAPGEF1,PTPN5,KAT7,BACH2,HLF,AGFG1,KIF5C,IPO5,CAMK2N2,MAG,MAPT,MAT2A,KITLG,MDGA1,NCAM1,NFIX,HCN1,IGSF11,CLDN11,ZNF827,PCDH8,PDE1C,PMP22,LRP12,TNPO2,NXPH1,CNNM2,TMEM260,REV3L,FIGN,LRRTM4,CASC3,KIF21A,CPEB3,SMTN,WDR47,SLC8A1,SLC12A2,SNCB,TMCC1,MYT1L,ZSWIM8,PLCB1,SYN2,SYP,SYT1,HHIP,FBXL16,NR2C2,FNDC5,FAM155A,AMOT,OSBP2,CELF4,EMSY,SCG2,SLC17A6,KAT6A,CERS6" MicroRNA hsa-miR-483-3p:mirSVR_highEffct hsa-miR-483-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.15E-53 1.77E-49 1.05E-52 9.71E-52 143 623 "KDM5D,NDRG3,ADAR,CC2D2A,OGT,ANK3,UPRT,ARRB2,ARSF,ASPH,NUMB,ATP1B3,SLC2A11,AZGP1,DDR1,RUNX1T1,METTL6,CDC27,CLCN3,QKI,LY86,RCHY1,ACBD5,ENTPD4,SNCAIP,CSNK1G3,NCAN,RIMS2,DCAF4,BOC,DCAF8,YTHDC1,DRD1,FAM78B,E2F6,AASDH,SNX29,FSD1L,FAM13A,ABI2,STX2,RCSD1,NSRP1,AMZ2,SLC9B2,FHL1,RGPD5,TACC2,ABLIM2,GABRG2,JPH4,RAPGEF6,KIAA1841,GGTA1P,RUNDC3A,RND1,ZNF638,GPD2,PRUNE2,GPM6B,TDRKH,CCDC184,RAPGEF1,GRIA2,GRID1,GRIK1,GUCY1B1,HNRNPK,SCIN,IL11RA,KCNA4,KCNN2,KCNN3,KLC1,SYTL4,MAT2A,MIA2,MSRA,NEFH,NELL1,SMIM11A,NTRK3,ODF2,PAH,PCMT1,PDE1A,MED1,CCDC144B,RASGEF1B,SAMD9,SLC22A23,PTN,TTC13,SH3TC2,RASGRF2,RBBP6,PNMA8A,ELP2,RPE,ZNF568,SATB1,SOX6,CPEB3,ST3GAL3,SLC6A8,SLC9A5,SLC22A4,SMARCC2,INTS9,RCOR3,LIMCH1,SOX3,UHRF1BP1L,RBM26,PBLD,MAPK8IP3,PHLDB1,GANAB,WWC1,ZEB1,WDR7,NAT16,ARHGAP9,FRYL,FBXL16,THRA,ERCC6L2,R3HDM1,C9orf85,SYNPO2,TSN,UBTF,VLDLR,XPO1,LGI4,ZNF154,STOX2,RNF103,UBE3B,FBXO36,MSRB3,GAN,SPATA13" MicroRNA hsa-miR-2116*:mirSVR_highEffct hsa-miR-2116*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.37E-53 1.89E-49 1.13E-52 1.04E-51 147 657 "ACADM,NDRG2,KLHL32,ELFN2,GALNT13,BEND6,INTS2,MTUS1,NUMB,ATP1B3,ATP2A2,CFLAR,NAE1,MTMR7,MAGI1,PLEKHB1,NRXN1,MYL6B,HECTD1,NIPBL,RCHY1,SEC24C,MICAL2,DZIP3,NRSN1,RUBCN,CYBB,GPRASP1,GAPVD1,ARMCX4,ZNF804A,SMG7,PLPPR4,DOCK2,DMTF1,EBF1,HIPK3,EGFR,KCTD3,ANKRD13B,SRRM1,FAM198B,TMEM132C,RACK1,FCGRT,KIAA1109,TMEM164,SUCO,PSD2,C2orf88,CELF1,ZMAT1,GABRA2,GABRA3,MTHFD2,DISC1,WASHC2A,ADAM28,GGTA1P,LILRB4,GRB10,GRIA2,ADAMTS13,AP4S1,ADAMTS6,MAEL,TLX1,IDH3B,C5orf24,RBPJ,CREG2,KIF5A,STMN1,MARK1,MBNL1,MDM4,POC1B,AFDN,MYH6,FXYD6,NEFM,NELL2,NTRK2,NUMA1,OPHN1,OXTR,GPR137C,TREM2,PDGFRA,PURG,PRIMPOL,EPB41L4B,DRAM2,CRLS1,PPP3CB,PRKACB,DIRAS2,PROX1,DCHS2,GON4L,PIGG,PLPPR1,STK32A,RASGRF2,KLHL11,ZFHX4,SCN8A,ITSN1,PAAF1,WDR37,SPHKAP,SORCS3,ANKRD36,LMBRD1,SOX3,ENKUR,KIF1B,NPAS3,SRPK2,ZNF302,APOM,SEPT8,FAM208A,ADGRL3,TMEM136,WDR7,SIK3,DICER1-AS1,TIAM1,ERCC6L2,PIK3R5,SMUG1,DCBLD1,RUSC1,RPL7L1,UBE2H,AMOT,LYPD6,DHX33,WNK1,MFF,CADM2,VPS35L,FAM47E,PCBP4,JMJD1C,SLC4A10" MicroRNA hsa-miR-571:mirSVR_highEffct hsa-miR-571:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.45E-53 1.94E-49 1.15E-52 1.06E-51 137 574 "CLK4,DSCAML1,ADD2,KIDINS220,BEND6,RTL9,MARCH4,APOC2,SHTN1,ARHGAP5,ATP1A2,SLC4A4,ATP2A2,ATP2B1,SEC11C,NRP2,PTBP2,CAPN3,VSTM2A,CERS5,TIGD7,CHM,CASC2,PPT2,QKI,ABCG1,PDE4DIP,CFAP61,PUM1,GPRASP1,RIPOR2,SPATA2,DDX46,SV2A,RABGAP1L,DMTF1,EDN3,ABI2,EML1,RABEPK,ERBB2,IGSF6,FCGR1A,FCGR3A,ZSCAN30,SPSB4,SYNCRIP,DCTN2,KHDRBS3,FYB1,STAG2,CHL1,GK,GOLGB1,GRID1,GRM7,LINGO1,RASSF8,OPALIN,IL6R,NME9,CREG2,KTN1,NCOA7,ZNF667-AS1,MAOB,MAT2A,PPM1L,NRBP2,NLGN3,SSH1,EPB41L4B,PPP3CC,PRKACB,HYDIN,LAMA1,OCIAD1,RAB5B,OXR1,RBBP6,GTDC1,RNASEL,RPRD1A,ZFHX4,ROBO2,RORB,EPHA10,BAALC,GLDN,ATAT1,RTKN,KCNIP1,CSRNP3,ASAP3,MYO18A,DOCK10,MAGI3,SLC1A6,SLC6A7,SLN,ZNF415,HECW1,NPAS3,LMO3,ZC4H2,LARP4,ADHFE1,GANAB,KLHL7,NECAB1,MTCL1,ROBO3,DNMBP,CAMSAP2,FAM208A,TCEA1,SATB2,RPGRIP1L,PCDHB7,SLC44A1,TLR4,C5orf64,ZNF384,CLHC1,CADM1,OSBP2,ZNF781,RICTOR,XPO1,TRIM9,FMN2,CELF4,ADAMTS9,SLC17A7,RTN4,ZNF248,FAM181A" MicroRNA hsa-miR-3155:mirSVR_highEffct hsa-miR-3155:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-53 2.09E-49 1.24E-52 1.14E-51 148 666 "TTYH1,DGCR6,ACHE,C3orf14,NDRG3,ERMN,ADORA3,PCDH19,TXNDC16,CC2D2A,ANK1,ALS2,ARSE,CAST,CDK11B,MAGI1,SRSF11,CLTA,ACBD5,SEC31B,CREM,ANKRD44,SNCAIP,CSF1,NCAN,FAM169A,RIMS2,DCAF4,RIPOR2,FRMPD4,PHF19,RHOBTB1,SV2B,RABGAP1L,DNM2,DPYSL2,EDNRB,SGK2,SEMA3D,EIF4G2,STARD3NL,EPHA5,EPHB1,ETV1,RTN3,EXTL2,TOMM40L,FDFT1,FGF1,SPSB4,FHL1,POLK,SARAF,AP4B1,ABLIM2,FAM120B,GAP43,WASF3,COPS8,GOLGB1,GRIA4,RFFL,GRIN1,GRM1,CLASRP,RNF165,MFSD2A,MAP4K5,GYG1,PADI2,NXPH2,DOCK7,SCIN,IL6R,KCND1,HECTD2,MAP2,MBD1,MOV10,PTOV1,SLC11A2,NUMA1,OGDH,GLIPR1L2,RETREG1,SMIM7,PLXNB3,ING3,PKN2,MAPK10,GRAMD1C,SAMD9,APTX,BDNF-AS,TMEM260,PTPRE,PTPRZ1,BSDC1,ZMAT4,TRIM68,REV3L,GTDC1,ARHGEF10L,SNX22,NEK11,GLDN,ABCA11P,SCP2,TNFRSF19,TRIM46,ARX,SLC6A1,SLC20A2,ZNF667,RIMS1,SNRPN,TNIK,SOX5,ZCCHC24,MYCBP2,KDM4C,CDK19,ST5,INKA2,GANAB,TACR1,TBCEL,TBL1X,WASHC4,GPRIN3,FRYL,CYB561A3,CRB1,TGFBR3,ENHO,TK2,TPM1,NPL,FNDC5,DNAJC12,LGI4,PROCA1,UPF3A,STOX2,LMAN2L,GAL3ST3,PPP1R3F,SLC4A10" MicroRNA hsa-miR-422a:mirSVR_highEffct hsa-miR-422a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.60E-53 2.58E-49 1.54E-52 1.42E-51 164 808 "KCNH8,SORCS1,ADRB2,SLC44A5,ARHGAP20,FAM135A,OGT,ALS2,DDO,TMEM263,CAPRIN2,EIF4G3,BCL2L2,ZNF599,CFLAR,IL33,CALB2,SLC25A14,CDH8,LGI1,TIGD7,PPT2,KIAA1549L,CLCN4,DNAJB5,C4orf33,LY86,AKAP7,AHCTF1,TOGARAM2,ZFP28,CDC42BPB,CREM,ARHGEF10,ERC2,PHF14,USP6NL,CCDC144A,RIPOR2,DCAF8,FRMPD4,DCC,DDX46,GRIN3A,DOCK2,DSCAM,DYRK1A,EBF1,WDPCP,HIPK3,RBM12,SH3GLB1,CELSR3,KMT5B,ENPP6,SPEG,FABP7,FCGR1A,CEP78,FCGR3A,FGF12,TMEM164,ATP5PD,FOXG1,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRB1,GABRG2,ERAP1,DISC1,GLS,CBX1,GNAS,GPT2,TDRKH,GRIA4,GRIK2,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,SMAP1,MYLK2,IL6ST,IL11RA,KCNJ10,KIF2A,KIF5C,MARK1,CTNNA3,MYCN,LYRM9,NAP1L3,NCAM1,NCAM2,NDP,NELL1,NEK1,NEUROD1,NF1,NFE2L2,CHAMP1,LOC100128398,PAK3,CAMKV,C11orf49,TRHDE,SCHIP1,PACSIN1,PRKACB,RAB39A,PRPSAP2,APTX,SIDT1,SNRK,USP47,FIGN,RFX4,RGS4,ELP2,UEVLD,FBXW7,BAALC,KIAA0895L,KCNIP2,KCNIP1,RXRG,ATF7IP,SORCS3,MBD5,IQSEC2,EPB41L3,NXT2,NEK4,PLCB1,CAMTA1,AGTPBP1,VWA3A,DMXL2,FRYL,TF,ZFPM2,AP4E1,GZF1,PPIL6,BEST1,GUSBP1,SLC26A10,EML6,ZNF189,UPF3A,SLC30A4,CADM2,PRTFDC1,STMN4,EPM2A,ST7,CAMK1G,ZNF248" MicroRNA hsa-miR-326:mirSVR_highEffct hsa-miR-326:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.75E-53 2.67E-49 1.59E-52 1.46E-51 151 693 "RALGAPA1,DGCR6,EMILIN3,SYS1,GPRIN1,ADARB2,PLEKHH1,ADORA2A,RNF150,KIDINS220,CASKIN1,ALAD,FAM135A,DOC2A,CDC42BPA,CACHD1,TMEM108,ALDH7A1,ATP6V1G2,BARD1,SEC11C,RGS9,NRP2,KSR1,CDC27,CDH8,RCBTB2,TMEM155,AKAP6,CHD1L,CSF2RA,LRIG1,MICAL2,OSBPL3,NCAN,APPL1,GIT2,HEPH,DLG3,USP3,MED12,DTNB,ABCC5,DNM1L,EBF1,SGK2,ASB3,SORBS3,C3orf18,SRRM1,ERBB2,CEP78,TOMM40L,PPP1R1B,FGF1,FGF11,FGFR1,ANKFY1,ARFGAP2,MSANTD4,TPPP3,ARPP21,ZNF274,DISC1,IGSF5,WASHC2A,USP19,GGT7,HPGDS,ZNF638,PSRC1,GPD2,BTN2A1,ZBTB49,IDH3B,ZNF181,IL11RA,LRRTM1,KIF5A,MAT2A,SYT9,MEST,CTNNA3,MYO7A,VWA2,SLC11A2,PAK3,PALM,PDGFRA,CYTL1,PLEC,PLXNB3,PURG,SCHIP1,SEPT4,PPP3CB,PKIA,CNTLN,C1orf109,NKAIN1,SLC25A48,OXR1,DBX2,BSDC1,EXD2,RORB,KCNIP2,DGLUCY,TNFRSF19,ZFP2,SEC14L1,ITSN1,MAGI3,FNDC3A,CTXN2,PAAF1,SLC22A4,ANKRD36,SNRPN,UNC80,ZSWIM8,NPAS3,SSPO,ERBIN,ELOVL4,ARC,WDR7,RNF216P1,CRB1,ITGB3BP,AP4E1,CDH22,ENHO,CDK20,TPM3,PRMT8,UBE2H,AMOT,UGT8,MTCH1,VLDLR,ZNF781,ELFN1,DHX33,LMAN2L,NAV2,PPP1R3F,SMIM8,CASC15,ACTR3B,ZNF248" MicroRNA hsa-miR-410:PITA hsa-miR-410:PITA_TOP PITA 4.92E-53 2.76E-49 1.64E-52 1.51E-51 109 364 "ACTN1,FMNL2,ELFN2,BCAR3,PARG,AQP4,CASK,ARHGAP5,NUMB,ATP2B2,JAZF1,CALB1,PTBP2,CLDN10,SRSF11,NRXN3,FAM19A5,CNR1,RCHY1,MYRIP,CREB5,PLCXD3,ST18,ARHGAP24,MATR3,IP6K1,RHOBTB1,SACS,DMD,DYNC1I1,DPYSL2,YAF2,KCNMB2,EPS8,ERBB4,DACH2,STAU2,PHYHIPL,GAB1,MSTN,ARFIP1,GFRA1,PCDH17,RND1,FERMT2,NUDT21,GRIA2,MAP4K5,HMGB1,AGFG1,SOWAHA,IGF1,NKD1,IL12A,ITPKB,MAP2,LRP1B,SCAMP5,MKLN1,NEXMIF,NDUFA5,NF1,NFE2L2,HCN1,PCDH8,CDK14,EPB41L4B,PPP3CA,PTCH1,MTMR10,PTX3,RDX,PBRM1,CARF,RORB,ELMOD1,CPEB3,CHD9,CPEB4,ANKFN1,PDZD2,SP4,C3orf70,SYN2,SYPL1,ANKRD12,CAMSAP2,WWC1,FBXW11,TCF4,TRIM2,TCF12,DOCK9,SLC35G2,TIAM1,RBFOX2,PDSS1,TRPC1,TMEFF2,VAV2,VSNL1,ZIC1,ZIC3,CSDE1,SNX27,RTN4,KAT6A,PHTF2,SOCS4" MicroRNA hsa-miR-1231:mirSVR_highEffct hsa-miR-1231:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.16E-53 2.90E-49 1.72E-52 1.58E-51 142 617 "NCKAP5,ACTN1,ERMN,FAHD2CP,BEND6,AMPH,UPRT,GPAM,AQP4,SEMA4G,ARNTL,RASL11B,KSR1,SGCE,BTRC,KALRN,PTBP2,PRC1,CCKBR,INA,TMEM257,CDH8,CDH18,LGI1,RAB33A,NRXN3,FAM189A2,QKI,IQCK,SUMF2,CREM,TRIM69,UBXN2A,GREB1,FRMPD4,IP6K1,AIF1L,DNAH9,DMTF1,DPP6,AASDH,EGFR,TMEM35A,STARD3NL,TMEM74,FGF14,FGFR1,FOXF2,FLT1,ZCCHC17,GABRB1,TRAF3IP2,JPH4,ARPP21,ZNF274,DISC1,SULT1C4,GHR,RAB30,GLS,WDFY3-AS2,CCDC184,STON1,AP4S1,PSIP1,ARHGAP36,VSIG4,HPSE2,SYNPO,SMAP1,IGSF1,SLC35G1,OLFM3,KCNMA1,MBP,MEIS2,MTR,LYRM9,NCAM1,NEFM,NOVA1,SLC11A2,GPR88,OPHN1,SNTG1,PDYN,MTRF1L,MBOAT7,PACSIN1,GRAMD1C,SAMD9,SIDT1,GDPD2,MDGA2,QRICH1,CNTLN,TMEM260,SUSD4,RASGRF2,ZYG11B,RFX4,NUDT11,RNASEL,KIAA0895L,GLDN,RPL38,ATAT1,DGLUCY,SEMA6D,SCP2,PPM1E,FRMPD1,FERMT1,NTNG1,RUFY2,ZNF430,SLC11A1,COLGALT2,SYNE2,DNAJC9,C12orf76,SMG6,SATB2,ZEB1,WDR7,TIAM1,MTMR14,TMPO,TRO,DCBLD1,RFTN2,SLAIN1,WIPF1,CELF4,REEP1,SYNC,FIP1L1,GOPC,SMIM8,MSRB3,GAN,FAM198A" MicroRNA hsa-miR-185*:mirSVR_highEffct hsa-miR-185*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.51E-53 3.10E-49 1.84E-52 1.69E-51 141 609 "ASPHD1,ASIC1,SYS1,ADRA1D,ZFAT,PI16,DGKZ,TNRC6C,MADD,CDK13,ATP2B1,GPC2,KALRN,RUNX1T1,P2RX6,TIGD7,CHGA,C7orf61,DNAJB5,CNGA3,CPS1,SH2B1,CLIP3,SEC24C,CSF3R,MICAL2,PDE4DIP,CTNND1,USP6NL,GAPVD1,ARHGAP24,PHF19,AIF1L,ZEB2,MYEF2,POM121,SMG7,SRGAP3,EXOG,FIS1,EDN3,SGK2,YAF2,PAN3,ERBB2,EXTL1,AMOTL2,IP6K2,IQCG,FLNC,FOLR2,USP21,PHYHIPL,MEGF11,MEGF10,ZNF234,DISC1,TTBK1,POLL,GNAO1,GPT2,PSRC1,GOLGB1,STON1,BTN2A1,CLASRP,MFSD2A,FAM107A,ARHGAP36,HTR5A,IGSF1,HES5,INPP5B,KCNA2,KCNJ9,KCNK3,MYO7A,SETD4,PAH,PALM,PDE1B,GPR173,CCSER2,FTO,PLTP,C11orf49,EPB41L4B,POLR2F,FSD1,PKN2,PTPRO,NKAIN1,CCDC40,SUSD4,KIAA0895L,ATAT1,SATB1,TRIM46,CASC3,ITSN1,SH3GL2,ASAP3,FUZ,NTNG1,FHOD3,EPN2,SIRT2,SLC14A1,NAXD,SORCS3,RCOR3,TTC17,CABCOCO1,WDTC1,SOX3,ERC1,NFASC,NKAIN2,DIP2A,CAMTA1,DNMBP,MGRN1,USP32P1,MTMR14,HEY1,C5orf64,CABIN1,TPM2,PRMT8,KCNE5,HEPACAM,GORASP1,BEST1,KLC2,ATP6V0E2,TMEM198,PCBP1-AS1,SLC30A3,DNALI1,NUP214,JPH3" MicroRNA hsa-miR-940:mirSVR_highEffct hsa-miR-940:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.57E-53 3.13E-49 1.86E-52 1.71E-51 162 791 "SYS1,TMCC3,GALNT13,SLC12A5,SORCS1,PTCHD1,ZNF608,KIAA1324,SPOP,CEP126,DOC2A,CNIH2,SUGT1P4-STRA6LP-CCDC180,UPRT,TNRC6C,CHRD,N4BP2L1,DPY19L3,CFAP410,LGI1,CFL2,RAB3C,DLGAP3,ZFYVE9,NRXN2,TPP1,TJP2,FAM149A,LETMD1,SLC4A7,HAPLN1,ANKRD44,CS,CSF3R,SIPA1L1,APPL1,CFAP61,DCAF4,GAPVD1,HP1BP3,SV2B,NTM,SGSM2,KBTBD11,DLG2,SLC12A6,ABCC5,EDIL3,EDNRB,CACNG7,YAF2,TNK2,STARD3NL,RASGRP2,STX2,SIRPB1,ACSL4,PRMT5,FAM49B,CAMKK2,TPPP3,ABLIM2,GABRA1,JPH4,INPP5K,ADAM28,CBX1,CCDC184,STMN2,HAS2,NXPH2,ICA1,RBPJ,IL6ST,KCND2,KCNK3,MAG,PIK3AP1,LYPLAL1,MATN2,CCDC80,CTNNA3,MYO9A,CCDC13,NF1,NME4,SLC11A2,NTRK2,NTRK3,NUCB2,PAH,PFKFB2,GDAP1L1,CAMKV,SMOX,TRHDE,SCHIP1,EPB41L4B,POU3F2,PPM1B,BDNF-AS,PTK2,PTPRE,PTPRH,PTPRN,RAP1GAP,ENOX1,MORC4,RFX4,RNF220,SLC25A36,DCUN1D2,ARMC5,CARF,ATP8B4,DGLUCY,CASC3,ZNF821,CCDC92,PPP4R3A,KANSL3,PKNOX2,SLIT1,RCOR3,SNRPN,PDZRN3,ZC4H2,ZSCAN29,FAM168A,FGD4,ZC3H4,SYN1,SEMA4A,CAMSAP2,SYNE1,FAM189A1,AKNA,USP32P1,GPRIN3,SIRT1,ZMAT3,ARL10,HEY1,PRRT1,TPM1,NPL,TPM3,METTL3,TRIO,TTTY15,CCDC136,CCDC14,CFAP298,FTSJ1,ZNF225,CADM2,MDH1B,EPM2A,CASC15,CAMK1G,NHSL1,AP3B2" MicroRNA hsa-miR-376c:PITA hsa-miR-376c:PITA_TOP PITA 6.22E-53 3.49E-49 2.07E-52 1.91E-51 99 298 "ABR,FAM43B,ADCY6,SLC12A5,PCDH19,ALCAM,AMPH,ANK1,MAP4K3,CNIH2,NCOA1,BCL7A,CACNA1G,LDLRAD4,CACNA2D1,CACNB2,CALB1,PTBP2,CHN1,RAB28,NRXN3,CLOCK,ERC2,TOX,KIF26A,RIMS3,MFAP3L,DLG2,DLX1,EDN1,FRY,PAN3,EN2,ANKFY1,DACH2,MEGF10,GABRG2,SPIN1,GPM6A,GRIA2,GRM3,ATXN2L,KLF12,HNRNPK,AGFG1,INSM1,SFXN5,NCOA7,CHIC1,MEF2C,MEIS2,SAMD5,NEXMIF,NCAM1,NEFH,HCN1,OPCML,XRN1,EPB41L4B,PKN2,PTPRD,TMEM255A,USP47,ARID4A,MSANTD2,RAVER2,ROBO1,RORB,CCDC112,SEMA6D,SATB1,SCN3A,FAM19A1,ABLIM3,SLC1A2,SLC8A1,SPHKAP,CPEB4,RCOR3,SNCB,TAB2,LARP4,ERBIN,TTBK2,DNMBP,ADGRL3,SATB2,RALYL,TIAM1,RIMBP2,TRPS1,SGK3,VLDLR,CELF4,SLC30A3,LRP8,KAT6A,HNRNPA3,KLHDC1" MicroRNA "CACTGCC,MIR-449:MSigDB" "CACTGCC,MIR-449:MSigDB" MSigDB 7.15E-53 4.02E-49 2.38E-52 2.19E-51 94 267 "ABR,ASIC2,PLEKHG5,TMCC3,ALCAM,ANK2,PPFIA1,PKP4,CNTNAP1,DGKZ,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,NRXN2,TMEM184B,AKAP6,MYRIP,CREB5,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,FOXG1,DPYSL4,ZCCHC17,BRPF3,CPLX2,NTNG2,LOXL3,GRID1,GRM7,CELF3,ATXN2L,KLF12,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,PDGFRA,GPR85,GDAP1L1,SEMA5B,STRN3,PKIA,SIDT1,EML5,TMEM255A,RALGDS,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,LRRC55,SPHKAP,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,SYT4,CAMTA1,CNTN2,SATB2,TCF12,AHCYL2,TPD52,MGAT5B,PLPPR2,LMAN2L,NAV3,NETO1" MicroRNA "CACTGCC,MIR-34C:MSigDB" "CACTGCC,MIR-34C:MSigDB" MSigDB 7.15E-53 4.02E-49 2.38E-52 2.19E-51 94 267 "ABR,ASIC2,PLEKHG5,TMCC3,ALCAM,ANK2,PPFIA1,PKP4,CNTNAP1,DGKZ,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,NRXN2,TMEM184B,AKAP6,MYRIP,CREB5,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,FOXG1,DPYSL4,ZCCHC17,BRPF3,CPLX2,NTNG2,LOXL3,GRID1,GRM7,CELF3,ATXN2L,KLF12,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,PDGFRA,GPR85,GDAP1L1,SEMA5B,STRN3,PKIA,SIDT1,EML5,TMEM255A,RALGDS,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,LRRC55,SPHKAP,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,SYT4,CAMTA1,CNTN2,SATB2,TCF12,AHCYL2,TPD52,MGAT5B,PLPPR2,LMAN2L,NAV3,NETO1" MicroRNA "CACTGCC,MIR-34A:MSigDB" "CACTGCC,MIR-34A:MSigDB" MSigDB 7.15E-53 4.02E-49 2.38E-52 2.19E-51 94 267 "ABR,ASIC2,PLEKHG5,TMCC3,ALCAM,ANK2,PPFIA1,PKP4,CNTNAP1,DGKZ,SYNJ1,WASF1,KYAT1,ZMYM4,EVI5L,NUMBL,NRXN2,TMEM184B,AKAP6,MYRIP,CREB5,CSF1R,CSNK1G3,RIMS4,CNTNAP2,PPP1R16B,CTNND2,BRINP1,ELMSAN1,B3GAT3,SGSM2,E2F5,APH1A,RGS17,ACSL4,SUCO,FOXG1,DPYSL4,ZCCHC17,BRPF3,CPLX2,NTNG2,LOXL3,GRID1,GRM7,CELF3,ATXN2L,KLF12,KCNH2,MAPT,KITLG,MPP2,CNOT4,NPTX1,PDGFRA,GPR85,GDAP1L1,SEMA5B,STRN3,PKIA,SIDT1,EML5,TMEM255A,RALGDS,FIGN,RIC8B,ZFHX4,LGR4,SATB1,SCN2B,ELMOD1,ITSN1,CPEB3,LRRC55,SPHKAP,SP2,ARHGAP26,POGZ,STAC2,SEPT3,PLCB1,SYT1,SYT4,CAMTA1,CNTN2,SATB2,TCF12,AHCYL2,TPD52,MGAT5B,PLPPR2,LMAN2L,NAV3,NETO1" MicroRNA hsa-miR-329-3p:Functional MTI Functional MTI miRTarbase 9.03E-53 5.07E-49 3.00E-52 2.76E-51 132 538 "CSMD2,ADCYAP1R1,PNMA8B,ESYT2,TAOK1,ATP1A3,ATP1B3,ATP2A2,BACH1,BSN,FOXK1,CA8,KALRN,TBRG4,CRLF1,CFL2,B4GALT6,STOML1,CLTB,TBPL1,ANKRD44,NOS1AP,MYADM,RIMS3,DNAL1,DBT,MED24,KLHL3,SV2B,MTX3,EGR3,SORBS3,EIF5,C8orf37,TUBD1,CHST15,SGIP1,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,EML4,RAPGEF1,PARD3B,GRIK3,CACFD1,NR3C1,ZNF496,GSTM5,IL1RAPL1,HLF,HMGCR,USP51,C2orf72,SCIN,IL6ST,ITPKB,KCNA4,KCNB1,KCNJ3,KLHL23,KCNK1,KIF5C,SYTL4,FGFBP3,AFF1,MOBP,JAKMIP3,HS6ST3,NEXMIF,TMOD2,PIK3R1,CRLS1,SNRK,PTCH1,RDX,ZMAT4,C12orf49,KIRREL1,SBF1,CSRNP3,ATXN1,SCN8A,GALNT10,TRA2B,WDR37,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,WDTC1,UNC5B,SS18,INKA2,AJAP1,NECAB1,TMEM178B,NAT16,ARHGEF12,GPRIN3,SIK3,HHIP,SLC44A1,GALNT17,TIAM1,NACC2,DDHD1,DAAM2,BEX4,DOK6,NR2C2,PRMT8,ZNF610,UBE2H,UBTF,UGT8,WNT7A,WRN,SF1,NDRG4,CRB2,ZXDA,LRP8,ADAMTS9,SIGLEC10,WNK3,MVB12B,FAM198A,SPATA13" MicroRNA hsa-let-7e:PITA hsa-let-7e:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,ZCCHC24,KIF21B,DDN,CLASP2,ELOVL4,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7g:PITA hsa-let-7g:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7d:PITA hsa-let-7d:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7c:PITA hsa-let-7c:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-miR-98:PITA hsa-miR-98:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7i:PITA hsa-let-7i:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7b:PITA hsa-let-7b:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7f:PITA hsa-let-7f:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-let-7a:PITA hsa-let-7a:PITA_TOP PITA 9.11E-53 5.12E-49 3.01E-52 2.77E-51 110 373 "PLEKHH1,UNC5A,SNX30,ADRB2,INTS2,KLHL13,PCDH19,ARHGAP20,BEGAIN,LCORL,MAP4K3,GAS7,SEMA4G,CHRD,NCOA1,SLC4A4,ATP2B1,ZNF583,NIPA1,TRIM41,USP6,MAP4K4,PCYT1B,AKAP6,SLC25A27,BTF3L4,AHCTF1,IGDCC3,PNKD,CRY2,RGS6,OSBPL3,PPP1R16B,SEC14L5,ZFYVE16,DAPK1,B3GAT3,BLOC1S6,DMD,CPEB2,DPH1,DYRK1A,ABCC5,GOLT1B,E2F5,EDN1,RASGRP1,EGR3,GOLGA7,EIF4G2,FGF11,ANKFY1,AFF2,GALC,C15orf41,GATM,CYP46A1,GNAL,GPR26,TMEM121B,CNTRL,CACFD1,ADAMTS8,LINGO1,DDX19B,HLF,SOWAHA,IGF1,NKD1,SCRT2,CHIC1,RSPO2,NAP1L1,NOVA1,PRTG,CDK14,PRRX1,PRKAB2,PKIA,PTPRD,RDX,DPF2,FIGN,KCTD17,ATP8B4,LGR4,RTKN,SCN4B,FNIP1,FNDC3A,WDR37,FAM214B,SLC6A1,SLC8A2,TRIM67,KIF21B,DDN,CLASP2,ELOVL4,SYT11,ANKRD28,ACSL6,KIAA0930,TNFRSF1B,TSC1,SMARCAD1,MEIS3,VANGL2,SOCS4,GAN" MicroRNA hsa-miR-639:mirSVR_lowEffct hsa-miR-639:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.31E-52 7.38E-49 4.34E-52 4.00E-51 128 508 "SERPINA3,DGCR6,CCDC85A,CC2D2A,SEMA6A,LTBP4,OGT,PARG,KIAA1614,SFMBT2,MARCH3,CCAR2,ATP1A2,SYNJ2,CACNA1D,CALB2,SYT6,CBR1,MAGI1,ASIC3,CASC2,SYNPR,NDST3,NRXN3,HECTD1,NIPBL,GDA,SNCAIP,CTH,RIMS2,DCAF4,NOS1AP,MYADM,SNPH,SPOCK2,SPOCK3,SRGAP3,HS3ST2,GPR61,ABI2,ELAVL2,EMX2,EPB41L2,RCAN2,ANKRD13B,NCALD,SPEG,MRPL10,RCSD1,ECSIT,EZH1,CLVS1,FGF14,CAP2,AGAP3,PCDH17,STARD3,GNAS,FUT10,NR3C1,LINC00839,CLASRP,KCND1,KCNJ16,KHK,CREG2,LSS,NAT8L,ZFYVE27,MBNL1,LDLRAD3,PPM1L,AFDN,NFE2L2,NFYA,NLGN3,PLXNB3,IRX1,PPP2R5C,KLK6,GDPD2,PTK2,PTPRE,RNASE1,NEK11,RPS6KA2,KCNIP3,ZNF331,SBF1,LRRTM4,SMPD3,GALNT10,COPZ1,ST3GAL3,ZNF365,SLCO1A2,LGI3,ARFGAP1,INAVA,SNRPN,ZSWIM8,TSPYL2,LMO3,SS18,DIP2A,DDHD2,CYB561A3,PMS2CL,TIAM1,MTMR14,TMOD1,R3HDM1,CSMD1,SEZ6L,SMUG1,RUSC1,VLDLR,SLC13A3,XRCC4,LGI4,EML6,PRDM2,DNALI1,PARP6,SEMA3B,HNRNPA3,PRRT4,JPH3" MicroRNA hsa-miR-151-3p:mirSVR_highEffct hsa-miR-151-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-52 8.67E-49 5.09E-52 4.69E-51 138 589 "SDE2,KCNH8,XKR4,ADD1,PWWP2A,ZNF608,NME5,TAOK1,SRPX,PCDH10,PPFIA2,PPFIA1,API5,AQP4,CHRD,NUMB,ATP2A2,WASF1,BTRC,CAST,KRIT1,LOC730101,CLTB,SULT4A1,NIPBL,ARMC8,CP,RNF14,RGS6,FEZ1,OSBPL3,SOCS5,NRSN1,CEP170,SPOCK3,DPYSL2,ABCC5,DNM1L,E2F6,FAM13A,MBNL2,EIF4G2,DCTN4,USPL1,TMEM74,DLC1,SUCO,DLL3,ZMAT1,GABBR1,CHL1,GABRB1,GALR1,C15orf41,LRRC37A6P,TUBGCP4,GHR,BRD8,GLS,GNAO1,GPD2,GPM6B,PCLO,GRM3,PSIP1,MIER3,LRRC75A,BRINP3,LRRTM1,LIG4,BEX5,GLIPR1L2,A2ML1,PRKACB,PKN2,MAPK8,VPS13C,ZIK1,PTPRZ1,PLEKHB2,OXR1,GTDC1,GSTCD,RPE,SPIN3,RYR3,STUM,TRA2B,HSPA4L,SHC4,PAAF1,SLA,FAM81A,WDR47,KDM4D,CCDC88A,SLCO1A2,ANKRD36,MBD5,ZNF415,USP33,NPAS3,CLASP2,EPB41L3,LRRC4,ERBIN,MLC1,KLHL4,ZEB1,PCDHB7,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,ZFPM2,AP4E1,TIAM1,TPD52,TPM1,NPL,STXBP4,UCHL1,TBC1D15,ZNF24,TRIM9,FMN2,SPIRE1,SMARCAD1,URM1,SLC17A7,WIPF2,WNK3,FXR1,NETO2" MicroRNA hsa-miR-3122:mirSVR_highEffct hsa-miR-3122:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-52 8.67E-49 5.09E-52 4.69E-51 138 589 "RALGAPA1,NCKAP5,GALNT13,ADD3,C1QTNF3,PCDH10,GPRASP2,SUGT1P4-STRA6LP-CCDC180,ATM,CDK5R1,CACNA1B,TRIM41,CAST,RUNX1T1,NDST3,IQCK,SUMF2,ABI3BP,GDA,PDE4DIP,ALKBH8,RABGAP1L,WDR20,ACOT8,ABI1,GNE,ARRDC4,TOM1,E2F6,PHC2,YAF2,PHF20L1,SUGP2,GOLGA7,PAN3,VPS13B,NCALD,ARMCX1,FCGR3A,ZNF589,OLFM1,CAMSAP1,IP6K2,C2orf88,ATP2C1,NRG3,STAG2,JPH4,NEK6,DISC1,TXNL4A,TNRC6A,ZNF638,MAP7D2,PCLO,GRIA4,FAM19A2,RNF165,MAEL,FRMD5,HMGCL,NEGR1,NKD1,USP54,LAMP2,STMN1,INSYN2,MBD1,NEXMIF,NME4,NOVA1,NPTX1,NTRK2,ODF2,OXTR,P2RX7,PCDH9,PCMT1,PCSK1,DUSP26,ZNF655,SNX10,PMP2,GRAMD1C,SAMD9,ANKHD1,PTPRE,TTC13,RFX2,GSTCD,MCMBP,ATP8B4,ABCA11P,PRCD,SUPT20H,SH3GL3,NTNG1,MAGI3,ZNF365,ABTB1,RCOR3,INAVA,RIMS1,CABCOCO1,SNRPN,KDM4C,CDK19,ATP10B,CLSTN2,SULF2,SEPT3,FGD4,SYN1,ANO4,TCEA1,ACSL6,TCF12,WDR7,SYNE1,OBSL1,VWCE,GZF1,ACTR6,TPM2,METTL3,SMUG1,RUSC1,RFTN2,TUBB2A,TMEFF2,LINC00689,VSNL1,ZIC1,EML6,SYNC,PRTFDC1,SIGLEC10,SLC4A10" MicroRNA hsa-miR-935:PITA hsa-miR-935:PITA_TOP PITA 1.87E-52 1.05E-48 6.15E-52 5.66E-51 96 282 "ABR,OSBPL6,LRRC7,PITPNM2,MAP4K3,APC,CDC14B,TMEM263,TMEFF1,CADPS,ATP1B3,NOL4,LGI1,CACNA2D2,MAP4K4,CREB5,CS,CSNK1G3,SOCS5,TOX,DBN1,ALKBH8,SRGAP3,ARNT2,DLG2,GRIN3A,DMD,CDON,MBNL2,EIF4G2,EIF5,GPHN,RTN3,GABRB3,CAB39,GAD1,SESN1,GGT7,SPIN1,GLUL,PCDH11X,MAP7D2,GPM6A,PTPRT,BACH2,MIER3,GABARAPL2,INSM1,KTN1,INSYN2,LIFR,LMO2,NCOA7,SMAD1,GPR155,MAT2A,MIA2,SCAMP5,GIT1,MYT1,NACA,CNOT4,KSR2,PDPK1,GPR85,OLA1,XRN1,PURG,FAT3,POU3F2,LRRN3,RELN,PTPRD,SH3TC2,RADX,SLC25A36,FBXW7,FBXO11,FNDC3A,SLC1A2,FAM81A,WDR47,EFHD1,CPEB4,FAM126B,SP2,CLSTN2,PRRC2C,ANKRD28,MGRN1,ACSL6,PUM2,HEY2,TP53BP1,PLEKHH2,ZFAND5" MicroRNA hsa-miR-3162:mirSVR_highEffct hsa-miR-3162:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-52 1.16E-48 6.78E-52 6.24E-51 143 632 "RALGAPA1,NDRG2,CCDC85A,BRAP,SORCS1,MTUS1,PLA2G6,ZNF578,ALCAM,ALS2,IGDCC4,SPTBN4,MYOM1,TTLL9,BACH1,BCS1L,NRP2,CASTOR3,CALM1,SLC25A14,CBLN1,CD38,NEURL1,LRBA,LARGE1,NRXN3,PPT2,COG1,TPP1,FBXO7,COL11A2,ABI3BP,TOGARAM2,SEC31B,RBM39,NCOR1,CLIP3,DOCK4,HDAC9,ARHGAP24,DCAF8,ZBTB24,MYEF2,HP1BP3,COPS7A,SV2A,GRIN3A,DTNA,MAMLD1,SEZ6L2,EDNRA,FAM13A,KMT5B,MRNIP,EPHB1,KCNMB2,IGSF6,CDHR1,RRAGB,EYA1,FGF12,TMEM164,PDLIM5,B3GAT1,ARPP21,GAP43,TUBGCP4,CYP46A1,RUNDC3A,HPGDS,PCDH11X,GOLGB1,PCLO,GRM1,KAT7,RASSF8,VSIG4,NKD1,ZNF385B,KCND1,KCNJ3,KLRC3,MAP2,MEIS1,MOBP,NEUROD1,SLCO1C1,CNOT4,NPR2,PBX1,PCSK1,EPB41L4B,PYGM,RAP1GDS1,ROGDI,KHDRBS2,RLBP1,SLC25A36,RIC8B,ATAT1,RTKN,SOX6,FNDC3A,CTXN2,SEC31A,ZNF365,PPP4R3A,SPHKAP,GKAP1,SORCS3,RCOR3,MBD5,TMCC1,WDTC1,UNC5B,DBNDD2,POPDC3,AGTPBP1,WDR7,PCDHB4,FRYL,AHCYL2,HIF3A,AP4E1,AKTIP,MTMR14,TMEM9,C5orf64,UBTF,PLEKHH2,BCL2L13,RICTOR,KCNT2,CELF4,POLR3H,CADM2,PCDH15,SLC17A7,LINC00632,MVB12B,FAM13C,UBE3B,IFT88" MicroRNA hsa-miR-3189:mirSVR_highEffct hsa-miR-3189:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-52 1.19E-48 6.98E-52 6.43E-51 128 510 "DGCR6,CSMD2,GALNT13,SLC12A5,KIDINS220,GPR158,ADGRF5,CCDC146,PKP4,ALS2,SHTN1,NUMB,SCAPER,CFAP410,SYT6,ARHGEF25,LDB2,IGFN1,CFL2,CHGB,CASC2,SYNPR,CLCN4,NIPBL,IQCK,HINFP,SIPA1L1,KIAA0040,ZFYVE16,ELMSAN1,ZEB2,SNAP91,SPOCK3,WDR20,DMD,OLIG1,F5,CORO2B,FGF12,IP6K2,NOP56,FLYWCH1,EFCAB2,ST6GALNAC3,BRSK1,ZMAT1,GAD1,DISC1,TUBGCP4,SULT1C4,USP19,GLS,LUZP2,EML4,GRIA4,PLPP7,KAT7,DDX19B,LINC00634,LMO2,ASPRV1,MARK1,TM6SF1,WDR49,SESN3,SCG3,MXI1,NAP1L2,NASP,NCF2,NELL1,DNHD1,PAH,CNTN3,NALCN,HMGCLL1,EXOSC10,PILRA,SH3KBP1,MED1,PPP3CA,PROX1,SNRK,PSMD13,MTMR10,PTHLH,PTPRD,FAM120C,VEPH1,RFX3,ARMC5,ROBO2,RPE,ATP8B4,ATAT1,LRRTM4,CASC3,MRAS,ST6GAL1,PAAF1,RIMS1,MBD5,KDM4B,UNC5B,ST5,ZSCAN29,GANAB,FBXW11,PCDHB10,TK2,ASXL3,PIK3R5,TRO,TRPC1,SSBP2,CLHC1,RPL7L1,UBE3A,MICU3,ZNF540,AGMO,EML6,ANKS1B,SPIRE1,LRP8,DOCK8,SSPN,IFT88" MicroRNA hsa-miR-1287:mirSVR_highEffct hsa-miR-1287:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.30E-52 1.29E-48 7.56E-52 6.97E-51 157 754 "EMILIN3,XKR4,SLC44A5,HECW2,UNC79,TNRC6C,SPTBN4,CDK13,CAPRIN2,ATM,ZNF583,NOL4,SEC11C,CFLAR,CA8,SPAG9,METTL6,INA,LRBA,ARHGAP33,CHN1,JAM2,PPT2,QKI,NIPBL,SUMF2,CREM,ANKRD44,GDA,FEZ1,GREB1,RIMS2,KIAA0408,TCAF1,TMEM170A,C8orf34,ELMO1,RAB39B,DTNA,ANKRD46,EFNB3,EGFR,TMEM35A,STARD3NL,CALCRL,RCAN2,LRRC17,CDKL3,EFEMP1,FKTN,TESK2,ZNF589,SLC9B2,FER,SGIP1,NOP56,NELFCD,SPECC1,AP4B1,OGA,DKK3,ZNF44,ARPP21,SULT1C4,MALT1,COPS8,KDM2B,PSRC1,GPM6A,MCHR1,GRIA4,ADAMTS13,LINC01551,PSIP1,MAEL,FRMD3,PLD5,IGSF1,ITPKB,SLC35G1,KCNB1,LIG4,AQP11,SYT9,ERICH3,CNOT4,LRIT2,P2RX7,PAK3,PBX1,PDCD2,GNG2,BEST3,DUSP26,MTRF1L,PMP22,EXOSC10,EPDR1,MASP1,PTAFR,ZIK1,OCIAD1,FAM120C,PID1,RAP1GDS1,DBX2,ZYG11B,RFX5,RIC8B,ZFHX4,CARF,LGR4,RPS20,ABCA11P,S100B,DGLUCY,AMER2,ELMOD1,CASC3,SH3GL3,FERMT1,FBXO11,EFHD1,CXXC4,SORCS3,PALLD,UNC80,SOX5,SOX15,ERC1,KIF1B,C11orf87,EPB41L3,DDHD2,VWA3A,ATMIN,SATB2,TCF12,USP32P1,AP4E1,GZF1,TLR4,ERCC6L2,TMOD1,R3HDM1,CHST5,VLDLR,KCNT2,EMSY,NAV3,PDSS2,EPM2A,RGS7BP,AMN1,PAK5,KAT6A,CASC15" MicroRNA hsa-miR-582-5p:TargetScan hsa-miR-582-5p TargetScan 2.67E-52 1.50E-48 8.77E-52 8.08E-51 121 457 "ERMN,GRAMD1B,BEND6,LRRC7,ANK1,APC,APP,LGR5,AQP4,MIER1,RASL11B,MTMR2,LDLRAD4,BRSK2,DGKI,CD81,CDH2,KCNAB3,CACNA2D2,NRXN3,FAM171B,CREM,HAPLN1,ANKRD44,CTH,GREB1,PYGO1,JAKMIP2,RAB39B,DMD,ABI2,EIF4G2,ELAVL3,RGS17,C8orf37,MTSS1L,EPS8,ETV1,MRVI1,MEX3B,FOXG1,B3GAT1,NCKAP1,GOLGB1,GPR34,GRID1,GRM5,IL1RAPL1,KLF12,HMGB1,HMGCR,HNF4G,HNRNPK,LRRTM3,JAK2,KCNB1,KCND3,GPR62,KCNN3,KCNQ3,KPNA5,PAXBP1,MARK1,MEIS1,MITF,MSI1,NCAM2,NFIA,NOVA1,HCN1,PDE4A,PDE4D,PFKFB2,GPSM2,PURG,SCHIP1,PRKACB,PTPRG,PEX5,GTDC1,ROBO2,RIMKLA,LGR4,SATB1,SCN4B,ITSN1,AMBRA1,FBXO11,FAM81A,CXXC4,KIF13A,MYT1L,KDM3A,NPAS3,NFASC,C11orf87,LARP4,FAM168A,ABCC8,NUDT10,CAMSAP2,ACSL6,NSD1,AP4E1,NACC2,CSMD1,KAT6B,RBFOX2,RASD2,RICTOR,KCNK12,DPYSL5,PMEPA1,RGMA,FZD3,RTN4,HNRNPA3,MSRB3,FRMD6,GAN,PRRT4" MicroRNA hsa-miR-544:PITA hsa-miR-544:PITA_TOP PITA 2.69E-52 1.51E-48 8.83E-52 8.13E-51 119 442 "ACLY,CCDC85A,CASKIN1,PCDH19,WDR35,OSBPL8,SPOP,ALCAM,ARHGAP20,AMPH,DPP10,MARK4,ASTN1,ATP2A2,MTMR9,MPDZ,CACNA1G,CACNA1A,CACNB4,CALM1,CAMK2B,CAMK2G,CBFA2T2,CDH2,DLGAP2,SOCS6,KMT2C,NIPBL,PCYT1B,RBM39,TENM4,GAPVD1,TOX,DAPK1,ALKBH8,SACS,CPEB2,ABI1,ARRDC4,DYRK1A,DNM1L,FRY,MBNL2,ABI2,PAN3,GPHN,KIAA1109,FGF12,STAG2,GABRA4,SALL3,PCDH17,PPARGC1A,PCDH11X,KDM2B,HTATSF1,PCLO,GRB10,ADAMTS6,HLF,HNRNPK,SMAP1,RBPJ,MAP2,MBD1,NELL2,NFIA,NFYA,CNOT4,NOVA1,GPR85,PIK3R1,FAT3,POU3F2,IRX1,RANBP3L,TMEM260,RET,RGS7,MCMBP,AMER2,SEMA6D,SATB1,ATXN1,FAM19A1,HSPA4L,SCAF8,NLGN4Y,CPEB3,EPN2,WDR47,CPEB4,SMARCE1,FAIM2,MYT1L,SOX11,SP4,ERC1,NPAS3,RAP1GAP2,CLASP2,LRRC4,PRRC2C,ATP11A,TAL1,CAMSAP2,TBL1X,TCF4,SLC35G2,AKTIP,TRPC1,TUBB1,CADM1,UGT8,SF1,CSDE1,DNAH10,PAK5,GAN" MicroRNA hsa-miR-362-3p:Functional MTI Functional MTI miRTarbase 3.59E-52 2.02E-48 1.18E-51 1.09E-50 131 536 "CSMD2,ADCYAP1R1,PNMA8B,ESYT2,TAOK1,ATP1A3,ATP1B3,ATP2A2,BACH1,BSN,FOXK1,CA8,KALRN,TBRG4,CRLF1,CFL2,B4GALT6,STOML1,CLTB,TBPL1,ANKRD44,NOS1AP,MYADM,RIMS3,DNAL1,DBT,MED24,KLHL3,SV2B,MTX3,EGR3,SORBS3,EIF5,C8orf37,TUBD1,CHST15,SGIP1,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,EML4,RAPGEF1,PARD3B,GRIK3,CACFD1,NR3C1,ZNF496,GSTM5,IL1RAPL1,HLF,HMGCR,USP51,C2orf72,SCIN,IL6ST,ITPKB,KCNA4,KCNB1,KCNJ3,KLHL23,KCNK1,KIF5C,SYTL4,FGFBP3,AFF1,MOBP,JAKMIP3,HS6ST3,NEXMIF,TMOD2,PIK3R1,CRLS1,SNRK,PTCH1,RDX,ZMAT4,C12orf49,KIRREL1,SBF1,CSRNP3,ATXN1,SCN8A,GALNT10,TRA2B,WDR37,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,WDTC1,UNC5B,SS18,INKA2,AJAP1,NECAB1,TMEM178B,NAT16,ARHGEF12,GPRIN3,SIK3,HHIP,SLC44A1,GALNT17,NACC2,DDHD1,DAAM2,BEX4,DOK6,NR2C2,PRMT8,ZNF610,UBE2H,UBTF,UGT8,WNT7A,WRN,SF1,NDRG4,CRB2,ZXDA,LRP8,ADAMTS9,SIGLEC10,WNK3,MVB12B,FAM198A,SPATA13" MicroRNA hsa-miR-500*:mirSVR_highEffct hsa-miR-500*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.66E-52 2.06E-48 1.20E-51 1.11E-50 138 593 "RALGAPA1,SLC25A25,NDRG2,BRAP,SUGT1P4-STRA6LP-CCDC180,APAF1,USP37,DDX3Y,TTLL9,SNAI3-AS1,DDR1,KALRN,CAMK2G,PRC1,CD38,CDH2,CHM,CNN3,BTF3L4,SLC4A7,FAM171B,SEC31B,HAPLN1,RNF14,SEC24C,PHACTR3,DOCK4,HDAC9,ZNF337,LIN54,MATR3,ZEB2,PLPPR4,SACS,SGSM2,DLG2,NR1D2,DRD1,ABCC9,ATL1,HIPK3,FCF1,EFNB3,TMEM132E,ELAVL2,DCTN4,RASL12,F8,SCML2,PRMT5,FOXG1,ATP13A4,NBEA,TACC2,NSG2,STAU2,ARPP21,MSTN,DHRS4,ZNF638,PRRC2B,GPM6A,GPR17,GRIK2,CIT,RNFT2,MAEL,GABARAPL2,IDH3B,RBPJ,USP54,SLC35G1,MATN2,MATN3,MBD1,MBNL1,MIA2,JAKMIP3,NEK1,GLIPR1L2,PCSK5,PDCD2,PDE4D,PLCB2,PLP1,POLG,PPP2R2C,PPP2R5E,PPP3CC,PLPPR1,BDNF-AS,RALGDS,SH3TC2,REV3L,FIGN,UBR7,RPRD1A,ZFHX4,EXD2,RPL15,UEVLD,FBXW7,ABCA11P,CLIP1,SATB1,SCN2A,ELMOD1,CNKSR2,PPP4R3A,DHX30,TET1,TRERF1,HECW1,KDM4C,IDI2-AS1,ZBTB43,SRPK2,ATP10B,NXT2,ACSBG1,PRRC2C,DDHD2,CAMSAP2,DOCK9,GPRIN3,DDHD1,HEY2,CSMD1,SMUG1,CADM1,UBE2H,MGAT5B,ZNF711,MAP3K12,PAK5,ADAMTSL3,JMJD1C,GAN" MicroRNA hsa-miR-1292:mirSVR_lowEffct hsa-miR-1292:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.68E-52 2.07E-48 1.21E-51 1.11E-50 141 618 "ABR,SYN3,PLEKHH1,LRFN2,AP1B1,OSBPL1A,SORCS2,ZNF578,ALAD,GPRASP2,FGD2,PPFIA4,ANXA7,CPNE5,SPTBN4,LINC00173,ASCL1,ADGRB2,SGCE,CACNA1D,CAMK2B,CANX,SHISA7,CCKBR,NEURL1,ZBED1,LOC730101,SRSF11,NDST3,PPT2,STOML1,CCDC151,SUMF2,MFSD4A,CPS1,CRY2,ANKRD44,RUBCN,MYADM,IP6K1,DCC,YTHDC1,DMTF1,SLC12A6,HIPK3,GOLGA7,COPS4,EIF1,KCNMB2,SRRM1,RTN3,RCSD1,TUBB3,SCML2,CHST15,FCGR3A,TESK2,FGF14,FOXF2,SYNCRIP,SEMA6C,SORBS1,ZNF605,NSG2,ZMYND11,NEK6,DISC1,SEPT9,LRRC37A6P,KIAA1841,GATM,MSTN,MSL3,CACFD1,NR3C1,GRM7,PADI2,CPT1C,MYLK2,ITPKA,KCNA6,KCNC2,KIFC3,LINC00634,TTYH2,LAMP2,MARK1,MEIS2,AFDN,STK32C,NCAM1,CNOT4,NOVA1,NRCAM,NRGN,LOC100128398,ZDHHC22,PDGFRA,KCTD15,FAM216A,EPN1,MAPKAP1,MBOAT7,VSTM2L,CEP41,RAB39A,RELN,TMEM260,PLEKHB2,RNF220,ROBO2,RXRA,AP1AR,SCP2,FBXO11,FHOD3,PPP4R3A,KDM4D,RAB3GAP1,ARFGAP1,ANKFN1,SOX1,C11orf87,ATP10B,PHLDB1,STX1A,STXBP1,TCF7,TPCN2,AZIN2,TIAM1,ERCC6L2,C5orf64,PPIL6,TMEFF2,CADM1,FAM155A,FLRT2,PLEKHH2,MICAL1,NETO1" MicroRNA hsa-miR-770-5p:mirSVR_highEffct hsa-miR-770-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.93E-52 2.77E-48 1.61E-51 1.49E-50 122 467 "CCDC85A,OSBPL6,CC2D2A,CARNS1,OGT,ANK3,FGD2,PHF12,AQP4,CHRD,EIF4G3,ADAM23,CBLN1,CNR1,RCHY1,SIPA1L1,GREB1,NRSN1,IST1,ARMCX2,ZNF804A,ZEB2,SACS,TMCC2,DNM1,CPEB2,SLC12A6,ABI1,DTNA,DNM1L,ABCC9,WDPCP,KMT5B,AASS,EMX2,RCAN2,EPHB1,KCNMB2,TLR7,RRAGB,ADGRV1,ST3GAL6,KAT8,ZNF589,SEC23B,ANKFY1,STAU2,DNER,NEU3,PCLO,RAPGEF4,GRIA1,GRIA2,TJAP1,IL6ST,METTL21A,KCNA2,KCNJ3,KCNK1,STMN1,ARHGAP12,MARK1,MATN2,ZNF680,ADAM22,MYO6,NAP1L1,NCAM2,P2RY1,PBX1,CDK18,PDGFRA,MAPKAP1,STRN3,NXPH1,PPP2R5C,CNTLN,PTX3,FAT4,RAP1GDS1,OXR1,HKR1,BSDC1,GTDC1,SLC25A36,CCDC82,ELP2,CCDC102B,NEK11,FBXW7,ATAT1,RYR1,ZNF331,RMI1,LRFN5,SH3BGR,HKDC1,MAGI3,FHOD3,ST3GAL3,ATF7IP,SMARCE1,SOX2,DOK5,SP4,POGZ,MESP1,ELOVL4,WDR7,PCDHB3,AHCYL2,ZFPM2,TP53BP1,PRMT8,HIRA,SGK3,ZNF138,ZNF154,ADAMTS9,TMEM178A,SCG2,SLC17A6" MicroRNA hsa-miR-512-3p:PITA hsa-miR-512-3p:PITA_TOP PITA 5.09E-52 2.86E-48 1.67E-51 1.54E-50 93 266 "SLITRK1,PTCHD1,PCDH19,RTL9,SPOP,PITPNM2,LRFN1,PPFIA2,TMEM263,ATP2B2,CACNA1A,PTBP2,LRBA,FOXN3,B4GALT6,KMT2C,CNR1,SLC25A27,ZNF385A,ARHGEF10,TOX,IP6K1,PLEKHM1,HP1BP3,SGSM2,DLG2,HIPK3,GPR61,MBNL2,KMT5B,PAN3,EPHA5,ERBB4,FGF13,AFF2,OGA,PHYHIPL,CHL1,GRM7,PTPRT,KAT7,HLF,KCNK2,NCOA7,SMAD9,MAT2A,MBNL1,SYT9,MXI1,MYT1,NEK1,OPHN1,PFKP,NALCN,TRHDE,PRRX1,PPARA,PPP2R5E,PPP3CA,PKIA,MAPK10,TMEM260,USP47,SLC6A15,SYNDIG1,SBF1,ATXN1,ATXN7,NTNG1,CPEB4,PALLD,TMCC1,MYT1L,SP2,CDK19,SS18,ERBIN,CAMTA1,TAL1,TCF4,TRIM2,WDR7,AKTIP,RELL2,ZFP91,NR2E1,ZNF711,CADM2,STMN4,MARCH8,KAT6A,ADAMTS10,ST8SIA2" MicroRNA hsa-miR-181c*:mirSVR_lowEffct hsa-miR-181c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.79E-52 3.25E-48 1.90E-51 1.75E-50 124 483 "SLITRK1,KIAA1324,AMPH,ANK2,EPB41L5,TMEM263,ZFYVE28,ARNTL,PDE8B,CAPRIN2,ASPH,ADGRB2,GYG2,CACNA1D,DGKI,CDH8,MS4A7,AKAP7,SLC25A27,CNRIP1,RBM39,ANKRD44,PDE4DIP,KIAA0040,UBXN2A,CTH,NRSN1,DOCK4,GAPVD1,KIF26A,RASSF2,KCTD8,DGCR5,G3BP2,NR1D2,DNM2,RCAN1,DTNA,ABCC5,EDIL3,PHF20L1,EIF4G2,LRRC17,KCNMB2,CACNG3,PRMT5,OLFM1,CAP2,FOXO3,ATP13A4,FLYWCH1,TBR1,DOT1L,GABBR1,GABRA2,BRPF3,GHDC,IQGAP2,LRRC37A6P,MSTN,SESN1,GLRB,STARD3,GNAS,ADGRA3,GPD2,GRM7,WIF1,MAEL,FRMD3,DDX19B,HMGB1,METTL21A,STXBP5,MAOB,MID1,FXYD6,NASP,CNOT4,IGSF11,PDE4D,XRN1,FAM216A,PPM1B,MASP1,OCIAD1,PTPRE,NKAIN1,PID1,ENOX1,ERI2,GTDC1,RFX3,ZFHX4,NEK11,ZNF568,SEMA6D,KIF21A,ANKRD6,SEPHS1,SLC8A1,SLC12A2,SLC20A2,NAXD,SMARCE1,RBM34,SP4,ZNF423,TAB2,TAL1,TF,HHIP,TMPO,TPM4,PDSS1,TRPC1,CADM1,PITPNB,VLDLR,LYPD6,WNK3,SLC17A6,ACTR3B,FAM219B" MicroRNA hsa-miR-421:TargetScan hsa-miR-421 TargetScan 8.22E-52 4.62E-48 2.69E-51 2.48E-50 103 332 "ABAT,C3orf14,APBB2,GAS7,AQP6,ARHGAP5,RIPK1,FUBP1,LDLRAD4,CAMK2D,MAP7,RUNX1T1,C1orf52,CFL2,CLCN3,QKI,NIPBL,ARMC8,MAGED1,NRG2,CS,APPL1,PLCXD3,CTH,DGKB,JAKMIP2,KIAA0753,EGFR,ABI2,PLXNC1,ELAVL2,ENPP6,EPS8,PIPOX,DNAJC27,FGF13,FGF14,FAM49B,NCKAP1,ATP8A2,CPLX1,GCNT2,GHR,PRUNE2,GRM8,KAT7,BACH2,AGFG1,IL6ST,KCNJ10,IPO5,MEF2C,MEIS1,MEIS2,MITF,MXI1,NCAM1,NFYA,CNOT4,OPA1,CLDN11,PDE4B,PDGFRA,PDPK1,PFKFB2,NLE1,PLCL1,EPB41L4B,PPP2R2C,KANSL1,PTPRB,OCIAD1,RDX,GTDC1,RORB,KIAA0895L,MCMBP,ATXN1,ELMOD1,ARX,BTBD3,CPEB4,FAM126B,ARHGAP26,C11orf87,LRRC4,MPRIP,GSE1,ARHGEF9,GPRIN3,FBXL16,ERCC6L2,CDK20,NR2C2,FRRS1L,FLRT2,CLIP2,POLR3H,ANKS1B,MAP3K12,KAT6A,GAN,CPNE4" MicroRNA hsa-miR-648:mirSVR_highEffct hsa-miR-648:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.93E-52 5.01E-48 2.92E-51 2.69E-50 129 524 "CSMD3,GRAMD1B,BCAR3,FAM135A,ALK,LCORL,MAP4K3,ZNF599,CALM1,PTBP2,USP6,CDC42,EVI5L,CFL2,CASC2,CNOT8,HECTD1,MAP4K4,SLC4A7,SLC35F1,NCAN,PDE4DIP,CTH,PUM1,ST18,FRMPD4,DGKG,TOMM20,COPS7A,RABGAP1L,CPEB2,DMTF1,AASDH,EDNRB,PHF20L1,EMX2,CEP85L,TLR7,ADGRV1,TOMM40L,FGF1,FGF12,SUCO,NELFCD,STAU2,OGA,FAM120B,MSTN,MALT1,GLS,GPD2,GPM6A,GRIA2,PRDM5,GRM5,LINC00839,MSL1,PLD5,USP54,METTL21A,KCNB1,ARHGAP12,MARK1,MAT2A,MEIS1,AFDN,MOG,BLOC1S2,NAP1L1,NF1,NRGN,NTRK3,GPR88,PAK3,PDE3B,FAM218A,PRRX1,PPP2R5E,PPP3CB,PKN2,SAMD9,CNTLN,RBBP6,TTLL7,RNH1,RAVER2,ROBO2,MRAP2,TMEM100,STK32B,ATAT1,TRAPPC13,SCN2A,HES6,SGK1,ITSN1,NTNG1,R3HDM2,BTBD3,SLC6A11,SLC14A1,BTBD7,ATF7IP,CPEB4,ZFP1,SORCS3,MBD5,KIF13A,SNRPN,POGZ,ANKRD28,DDHD2,ANO4,DMXL2,SATB2,TEK,LRRC8A,TMPO,TP53BP2,TPD52,NPL,PPIL6,DCBLD1,EMSY,STOX2,PDSS2,JMJD1C,NETO1,PRRT4" MicroRNA hsa-miR-299-3p:mirSVR_highEffct hsa-miR-299-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.19E-52 5.16E-48 3.00E-51 2.77E-50 140 614 "CLK4,KLHL32,ADD1,ADD2,ERMN,GPR158,RTL9,FAM135A,ANK3,USP28,APC,ALS2,USP37,MADD,ZBTB10,TMEM108,ATP2A2,ZNF583,RGS9,CACNB2,KALRN,RUNX1T1,CERS5,CBFA2T2,TIGD7,CLGN,DLGAP3,NRXN1,TMEM155,IQCK,FAM149A,BTF3L4,SLC35F1,ANKRD44,CSNK1G3,HDAC4,BRINP1,ZBTB24,HP1BP3,FBXL5,RHOBTB1,GRIN3A,E2F6,EDN1,SYT15,PHF20L1,SORBS3,TMEM35A,EPB41L2,RABEPK,MRPL37,CACNG3,C1orf61,CAP2,NEURL4,ZNF44,ZMYND11,DISC1,INPP5K,GGT7,BRD8,KDM2B,FUT10,GPR22,DIDO1,GRM8,LINC00839,KAT7,RNFT2,HMGB1,SHISA6,KNDC1,USP54,SLC35G1,KCNMA1,PAXBP1,NCOA7,MBNL1,MSR1,MTTP,LAYN,NF1,VWA2,NTRK3,OPA1,P2RX7,PDE3A,GNG2,FAM218A,HMGCLL1,PLTP,PMP22,SEPT4,PKIA,SLC26A11,PTPRG,TUG1,PLEKHB2,RFX4,RGS4,KCTD17,SNX22,BAALC,KCNIP3,RTKN,FAM182A,ITSN1,CHD9,CLSTN1,SLC1A7,SMTN,RIMS1,DOP1A,MYT1L,SOX5,SP4,COLGALT2,ZC4H2,MAPK8IP3,STAU1,ABCC8,VPS13A,PLCB1,TACR1,TBX15,TCF4,OBSL1,FRYL,TPM4,STXBP4,UBE2H,PITPNB,CCDC14,MAP3K12,LINC00632,FAM13C,UBE3B,CASC15,FRMD6,RNF146" MicroRNA hsa-miR-3142:mirSVR_highEffct hsa-miR-3142:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.17E-51 6.55E-48 3.81E-51 3.51E-50 142 632 "SERPINA3,ACADM,ABCD2,OGT,ANK2,PPFIA1,PKP4,CASK,NCOA1,ADAM23,DCAF5,ZNF599,PRC1,METTL6,ARHGEF1,LRBA,LGI1,CHN2,CASC2,JAM2,EPS15L1,QKI,ABI3BP,CLOCK,AKAP12,MICAL2,VCAN,SOCS5,PDE4DIP,HDAC9,PHF19,TMEM170A,DCC,DNAJC6,ZEB2,WDR20,DLG2,ARRDC4,DTNA,EBF1,SGK2,PHF20L1,C3orf18,EML1,PAN3,RASGRP2,MRPL37,RCSD1,SIRPB1,EYA1,TESK2,MED12L,FGF1,IP6K2,ZMYND15,SEMA6C,JKAMP,ST6GALNAC3,STAU2,DKK3,GABRA1,ILDR2,AHCYL1,KIAA1841,DNER,SRCAP,MMADHC,PPARGC1A,COPS8,FERMT2,GOLGB1,GPD2,GRIA2,GRIA4,FAM19A2,KAT7,HSF2,FAM95B1,LINC00667,OLFM3,KCNK2,KCNMA1,ZFYVE27,MRPL42,MT3,NTRK2,NTRK3,OPHN1,SEMA5B,ANLN,PURG,PMP2,PILRA,PPM1B,PPP2R5E,PPP3CA,MAPK9,VPS13C,BDNF-AS,PTPRE,TUG1,ZNF493,SLC6A15,TRIM68,RGS3,SEC61A2,PBRM1,RPRD1A,YY1AP1,ZNF671,MCMBP,ATXN7,HOGA1,LRRTM4,SCN7A,CASC3,NTNG1,RUFY2,ZNF430,MYO16,SON,LMO3,TAB2,CAMSAP2,TBCEL,TCF12,SYNE1,DOCK9,RNF216P1,SYNPO2,STXBP4,CCDC14,NSD2,SF1,ZNF154,UPF3A,MFF,SCG2,RGS7BP,AMN1,SMIM8,SLC4A10" MicroRNA hsa-miR-544b:mirSVR_highEffct hsa-miR-544b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-51 7.80E-48 4.53E-51 4.17E-50 132 550 "KCNH8,EMILIN3,NDRG2,KLHL32,SORCS1,CC2D2A,AK2,UPRT,ZFYVE28,ARRB1,CDK13,ATP2B1,RGS9,SGCE,MYRF,CALM1,SLC25A14,CAST,CBR1,CLDN10,AIFM1,TIGD7,NDST3,LY86,IQCK,ABI3BP,PNKD,CREM,HINFP,SNCAIP,SEC24C,EDRF1,IST1,HEPH,EXOG,DMTF1,DPP6,ARRDC4,DTNA,ABCC5,PHC2,FAM13A,APH1A,PLEKHA1,RGS17,EML1,PAN3,EN2,DNAJC27,SIRPB1,CACNG3,CAP2,NOP56,B3GAT1,GALR1,DISC1,NEU3,LOXL3,GNG3,TDRKH,CCDC184,PCLO,GRIA2,ATE1,GRM5,COQ10A,NME9,PAXBP1,MARK1,MAT2A,MBD1,MIA2,POC1B,JAKMIP3,MSRA,CTNNA3,NAP1L1,CCDC13,DNHD1,OGG1,GPR137C,PDCD2,CAMKV,ZNF655,PURG,EXOSC10,SDK2,SH3KBP1,PPP3CA,PPP3CB,PKN2,CNNM2,WDR25,PTK2,SLC25A48,ENOX1,OXR1,SLC6A15,C12orf49,EMID1,ITSN1,FAM214B,ZNF667,ANKRD36,SON,ZC4H2,NKAIN2,RGL1,ADHFE1,MCF2L,VWA3A,CRB1,SLC44A1,MTMR14,ERCC6L2,PRRT1,CDK20,SMUG1,AMACR,HEPACAM,UBE2H,VLDLR,XRCC4,MICU3,ZNF189,MEIS3,CADM2,LINC00632,AMN1,FBXO36,SSPN,NETO2" MicroRNA "TGCTTTG,MIR-330:MSigDB" "TGCTTTG,MIR-330:MSigDB" MSigDB 1.60E-51 9.00E-48 5.22E-51 4.81E-50 100 314 "ADD3,SORCS1,GPRASP2,AMPH,OGT,DPP10,APBB2,APC,GPAM,API5,TMEM263,ATP2B1,ATP2B2,MTMR9,BACH1,BTRC,CA12,CBFA2T2,DCLK1,FOXN3,NRXN3,QKI,PCYT1B,CSNK1G3,TOX,MAML1,CEP170,FAM107B,DLX1,DYRK1A,PHC2,EFNA3,RBM12,MBNL2,GPHN,PPP1R1B,FGFR1,FOXG1,PDLIM5,NSG1,ARPP21,PCDH11X,GNAO1,GPM6A,GRID1,GRM5,RNF165,SOX21,CELF3,LRRC75A,KCNA6,MBNL1,LRP1B,MEF2C,ZC3H12B,PCMT1,PPM1B,KANSL1,PRKCB,DIRAS2,KCNIP2,TRA2B,SH3GL2,PPM1E,SYBU,SLC8A3,PDZRN3,ZCCHC24,SOX11,SP4,ZNF423,KIF1B,SRPK2,STAU1,ARHGEF9,PLCB1,SYT5,TCF12,PCDHAC2,PUM2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TGFBR3,TJP1,TPM3,TRPS1,AMOT,MTCH1,PRTFDC1,LRP8,PRDM8,ITM2C,SLC17A6,SLC4A10,JPH3" MicroRNA hsa-miR-1256:mirSVR_highEffct hsa-miR-1256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.72E-51 9.64E-48 5.59E-51 5.15E-50 140 617 "KCNH8,LRRC7,MARCH4,PCDH10,DPP10,FGD2,API5,AQP4,ARRB1,PLA2G4C,ASGR1,CAPRIN2,ZNF582,SLC2A11,N4BP2L1,ATP6V0A1,BMPR1B,C1QC,CACNA1B,CD38,LOC730101,CFL2,SRSF11,SOCS6,CPNE6,PPT2,CNR1,AKAP7,AKAP6,COL4A5,SLC4A7,MYRIP,CREM,CLIP3,SNCAIP,CSNK1E,VCAN,CFAP61,CTNND1,CYBB,IP6K1,DBI,DDX46,RHOBTB1,AK5,DPP6,DTNA,E2F5,EDNRA,EMX2,TMEM132C,SLC9B2,OLFM1,FOXG1,NOP56,CAMKK2,ZNF605,CAB39,ARPP21,ZNF234,ERAP1,NEU3,GPD2,PRUNE2,RFFL,GRIK2,NR3C1,RNFT2,FRMD3,ELOVL5,HMGB1,C9orf129,FAM95B1,C2orf72,ZIC5,RBPJ,LIG4,CLEC18A,EFHB,CD200,MTTP,MTR,NFE2L2,NTRK2,NUMA1,P2RY1,PCDH9,PCSK2,PDE1C,GPR85,PIK3C2A,MTRF1L,PDZRN4,ING3,DRAM2,MAPK9,MASP1,SIDT1,PTHLH,PEX2,TMEM255A,SH3TC2,SLC6A15,RGS3,RGS7,NUDT11,RORB,AP1AR,SALL1,SCN8A,SCP2,SGK1,ITSN1,CCDC88A,DMRTC1,SMARCE1,SNRPN,SOX5,DDN,TAB2,STOX1,SYNE2,VPS13A,ANKRD28,UNC5D,ANO4,DMXL2,ZFP90,CUX2,SYNE1,TEX15,ASXL3,NR2E1,METTL3,PRMT8,STXBP4,BCL2L13,TRIM9,DNAH10,PHTF2" MicroRNA hsa-miR-597:mirSVR_highEffct hsa-miR-597:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.85E-51 1.04E-47 6.04E-51 5.56E-50 123 480 "ASIC2,PWWP2A,SLC24A4,GPR158,PLA2G6,C1QTNF3,LRRC7,SRPX,ANK2,LRRC4C,DNAH17,ATP6V1G2,CACNA1E,CACNB2,PTBP2,VXN,CAST,METTL6,CFL2,CHGB,CHN2,NRXN3,NIPBL,RCHY1,MYRIP,SLC35F1,GDA,ARHGEF4,RUBCN,FGFR1OP2,ARMCX4,DCC,FBXO25,G3BP2,DMTF1,DNAJB6,E2F6,FAM135B,FSD1L,YAF2,SH3GLB1,NCALD,FGF14,AGAP3,PSD2,PDLIM5,MSANTD4,IP6K3,GLYR1,GLS,CNDP1,GPD2,GPM6A,GRIA4,GRIK1,GRIK2,RNF165,MAEL,TLX1,USP51,NEGR1,HSF2,IL6ST,ZNF678,JAK1,KCNA2,KCND2,KCNK2,VWA5A,HECTD2,MBD1,KITLG,MXI1,NAP1L2,NCAM1,CNOT4,PDE1C,SEPT4,EPDR1,MAPK9,GRAMD1C,MASP1,RELN,WBP1L,PEX5,NUDT11,RNASEL,EXD2,NEK11,NCBP3,SEMA6D,ATXN7,SCN2A,LINC00461,STUM,ASRGL1,SGK1,CPEB3,FHOD3,SLITRK3,BTBD3,SMARCE1,RCOR3,UNC80,PDZD2,SP4,RGL1,GANAB,SZT2,OBSL1,THRA,TMOD1,KAT6B,FNDC5,RPRM,SLAIN1,BEST1,ZNF19,SH3GLB2,TMEM178A,CIAPIN1,FIP1L1,SMIM8" MicroRNA hsa-miR-1205:mirSVR_highEffct hsa-miR-1205:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-51 1.13E-47 6.54E-51 6.02E-50 155 748 "KCNH8,SYN3,BRAP,KIAA1211,KIAA1324,OSBPL8,CC2D2A,AMPH,ANK2,CNIH2,SUGT1P4-STRA6LP-CCDC180,ALS2,SLC4A4,B3GALT2,DPY19L3,TTLL9,ST3GAL5,ARHGEF7,CACNA1A,CALB2,KALRN,SLC25A14,CAST,RUNX1T1,INA,DGKI,LRBA,CHI3L2,KMT2C,COG1,LETMD1,CRY2,GDA,KATNAL2,RIPOR2,KCTD8,IST1,DDX46,SMG7,SRGAP3,G3BP2,EXOG,DNAH9,AASDH,KLHL5,YAF2,ABI2,EML1,DCTN4,MFSD10,LRRC17,EPHA5,GPHN,GMPR2,CD320,CLVS1,RACK1,TOMM40L,FCGRT,FHL1,SYNCRIP,ZCCHC17,TMEM107,ATP2C1,ERGIC3,DKK3,GABRB1,FAM120B,ZNF559,DNER,COPS8,MAP7D2,TDRKH,RAPGEF1,ADAMTS13,CLASRP,TNFAIP8L3,GABARAPL2,DISP2,KCND2,GATD1,IPO5,MAT2A,MBD1,POC1B,MMP16,MOG,MYO9A,RTL5,NF1,CNOT4,OXTR,P2RX7,PDE3B,PDGFRA,ENPP2,TMIE,RETREG1,FAM216A,NXPH1,RASGEF1B,RAB39A,EPDR1,RELN,KLK6,APTX,TMEM260,TMEM231,TTLL7,RPL15,HSD11B1L,ATAT1,FAM192A,SEMA6D,SATB1,ATXN7,SCN2A,SCN8A,ZFP2,SGK1,ITSN1,SH3GL2,HKDC1,SLC6A8,RAB3GAP1,SLC11A1,SLC15A2,SLC22A4,ANKRD36,UNC80,MYT1L,KDM3A,CLUAP1,SSPO,STAU1,COBL,SLC37A2,FBXW11,ZFP90,RPGRIP1L,AKNA,FRYL,AP4E1,BEST1,PCDH20,ATP6V0E2,ZFAND5,UPF3A,SLC30A4,DNALI1,ADAMTS9,PCBP4,WNK3,UBE3B,FRMD6" MicroRNA hsa-miR-296-3p:mirSVR_highEffct hsa-miR-296-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.14E-51 1.20E-47 6.97E-51 6.42E-50 126 504 "TTYH1,FMNL2,ERMN,OSBPL1A,C1QTNF3,AMPD2,PPFIA4,PHF12,SUGT1P4-STRA6LP-CCDC180,ALS2,CADPS,MARCH3,ASTN1,ATP2A2,ATP6V1G2,ADAM23,CAMK2D,CAST,DLGAP1,TIGD7,SRSF11,SOCS6,CASC2,CPNE6,CNTN1,AKAP6,CSF2RA,PDE4DIP,PNPLA8,CTNND2,CX3CR1,KATNAL2,DCAF8,ZFYVE16,PITPNC1,JAKMIP2,DTNA,ECM2,EBF1,EDIL3,KLHL5,PAN3,EIF1,ENO2,CHST15,IP6K2,SMC2,FAM49B,NRG3,STAG2,GABRA2,JPH4,GAP43,ADAM28,TCERG1,RAB30,GNAO1,ZNF782,GRIN2D,GRM3,GRM7,LINC00839,TCEAL6,KIAA1755,IL6ST,LRRTM3,KIF5C,ZNF667-AS1,MATN2,MBD1,ERICH3,FXYD6,IGSF11,PAK3,PDE2A,PDGFRA,SERPINE2,PLIN1,PLP1,STRN3,ING3,SEPT4,DRAM2,MAPK10,PTCH1,TMEM260,PTPRD,ZNF844,ZNF493,RBBP6,MSANTD2,KIF7,PBRM1,CCDC82,NEK11,RPL15,FBXW7,PTGR2,ATAT1,ATXN7,FAM19A1,SCN8A,ASAP3,ABLIM3,ZNF334,SCMH1,MYO16,ERC1,POGZ,NKAIN2,TACR1,DDHD2,UNC5D,TCF7,TRIO,AMACR,FNDC5,TBC1D15,ZNF28,NDRG4,ZNF138,FTSJ1,LMAN2L,C12orf4,FZD3,CASC15" MicroRNA "AAGCCAT,MIR-135B:MSigDB" "AAGCCAT,MIR-135B:MSigDB" MSigDB 2.23E-51 1.25E-47 7.26E-51 6.68E-50 100 315 "DPF1,MTUS1,ANK3,ANXA7,CNTNAP1,GAS7,API5,PDE8B,NCOA1,DDX3Y,ATP2B2,ATP2B3,BACH1,ARHGEF7,BSN,CACNA1D,CACNA1E,KALRN,NEURL1,ARHGEF2,KCNAB3,DLGAP2,FOXN3,SLC24A2,QKI,ARHGEF6,PCYT1B,ZNF385A,SLC35F1,ENTPD4,CREB5,ARHGEF4,RIMS2,LONRF1,PITPNC1,MYEF2,SRGAP3,DLG2,CALN1,GOLGA7,EXTL2,WAC,RGPD5,SYT3,NBEA,STAMBP,ZNF44,GABRG1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,GLRB,GPM6B,PSIP1,HPS5,NEGR1,SHISA6,IL6ST,ZNF385B,JAK2,KCND1,KCNMA1,MAT2A,MEF2C,PDE4A,GPR85,DRAM2,PPP2R5C,DIRAS2,SNRK,ELOVL2,PTK2,SEMA6D,SCN2B,MRAS,MAPKBP1,FAM219A,SON,MYT1L,RGL1,C3orf70,PLCB1,ANO4,CUX2,WASHC4,SIRT1,SLC44A1,FBXL16,TMEM9,TRPC1,FNDC5,VLDLR,NDRG4,EVI5,STMN4,ADAMTS9,PAK5,PHTF2,SOCS4" MicroRNA "AAGCCAT,MIR-135A:MSigDB" "AAGCCAT,MIR-135A:MSigDB" MSigDB 2.23E-51 1.25E-47 7.26E-51 6.68E-50 100 315 "DPF1,MTUS1,ANK3,ANXA7,CNTNAP1,GAS7,API5,PDE8B,NCOA1,DDX3Y,ATP2B2,ATP2B3,BACH1,ARHGEF7,BSN,CACNA1D,CACNA1E,KALRN,NEURL1,ARHGEF2,KCNAB3,DLGAP2,FOXN3,SLC24A2,QKI,ARHGEF6,PCYT1B,ZNF385A,SLC35F1,ENTPD4,CREB5,ARHGEF4,RIMS2,LONRF1,PITPNC1,MYEF2,SRGAP3,DLG2,CALN1,GOLGA7,EXTL2,WAC,RGPD5,SYT3,NBEA,STAMBP,ZNF44,GABRG1,B4GALNT1,RAPGEF6,CPLX2,CPLX1,GLRB,GPM6B,PSIP1,HPS5,NEGR1,SHISA6,IL6ST,ZNF385B,JAK2,KCND1,KCNMA1,MAT2A,MEF2C,PDE4A,GPR85,DRAM2,PPP2R5C,DIRAS2,SNRK,ELOVL2,PTK2,SEMA6D,SCN2B,MRAS,MAPKBP1,FAM219A,SON,MYT1L,RGL1,C3orf70,PLCB1,ANO4,CUX2,WASHC4,SIRT1,SLC44A1,FBXL16,TMEM9,TRPC1,FNDC5,VLDLR,NDRG4,EVI5,STMN4,ADAMTS9,PAK5,PHTF2,SOCS4" MicroRNA hsa-miR-1276:PITA hsa-miR-1276:PITA_TOP PITA 3.09E-51 1.74E-47 1.01E-50 9.26E-50 104 343 "INTS2,KLHL13,PCDH19,LRRC7,SEMA6A,ALCAM,AMPH,DPP10,MAP4K3,APC,DDX3Y,ATP1A3,ATP2B1,FUBP1,MTMR3,JAZF1,SPAG9,CERS5,TMEM184B,RBM39,CNTNAP2,CTNND1,CTNND2,GAPVD1,ZFYVE16,MAML1,IP6K1,ELMSAN1,POM121,SMG7,G3BP2,DLX1,GRIN3A,DRP2,DUSP9,ST8SIA3,STARD3NL,PAN3,EN2,MED12L,AGAP3,SORBS1,AHCYL1,BRPF3,ARFIP1,SPIN1,TNRC6A,PRRC2B,PCLO,GRB10,GRID1,FAM19A2,KLF12,HNRNPK,C5orf24,ITGAV,KCNK2,MARK1,MAT2A,LRP1B,KITLG,MITF,NEK1,PENK,OLA1,EPB41L4B,NXPH1,PPP2R5C,CEP41,PTPRD,FAM120C,OXR1,RNF220,CARF,RORB,SNX22,LRRTM4,PPM1E,KBTBD4,CPEB4,KDM4B,SOX11,CDK19,NFASC,MPRIP,NECAB1,SYNE2,SYT1,ANKRD12,CAMTA1,FBXW11,TCF4,ARHGEF12,PUM2,SIRT1,ZFP91,TRPS1,ZFP37,CADM2,NAV3,WIPF2,PHTF2,FRMD6,NETO2" MicroRNA hsa-miR-1193:mirSVR_highEffct hsa-miR-1193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.28E-51 1.84E-47 1.06E-50 9.80E-50 133 562 "SYN3,CSMD3,PWWP2A,ADGRF5,LRRC7,ARHGAP20,VAT1L,PPFIA3,ARHGDIA,ATP1A1,LINC00847,SYNJ2,CACNB2,LDB2,CDC42,SRSF11,CHN2,PLEKHB1,COG1,LETMD1,CSF1,CYBB,ZNF337,MYEF2,FBXL5,ZC3H11A,SEC16A,ZNF582-AS1,NR1D2,CNNM1,MBNL2,EIF4G2,RABEPK,EXTL2,CORO2B,POLR1B,ST6GALNAC3,RAPGEF6,TUBGCP4,MSTN,SPIN1,GLUL,ZNF638,GPD2,GPM6A,PCLO,RAPGEF4,ATP2B1-AS1,GRIK3,GRIN1,CIT,RNF165,PTGDR2,MAN1B1,HNMT,HSPA1L,SHISA6,SMAP1,RBPJ,ITGAV,KIT,KPNA5,VWA5A,MAN2A2,SYT9,MEIS2,ZNF680,NELL1,VWA2,LOC100128398,SNTG1,PDE3B,PDE4D,PDE1B,PDGFRA,NLE1,FXYD1,SPATA6,TATDN3,GRAMD1C,VPS13C,PTK2,PTPRD,PTPRO,KCTD17,SETD5,ADAL,ACER3,LRRK2,LRFN5,SCN8A,ASIC4,SH3GL2,CHD9,RUFY2,KDM4D,SEPHS1,SLC8A1,SLC15A2,BTBD7,TET1,SMARCE1,ANKRD36,CMTR2,KIF21B,NMNAT2,DBNDD2,TAB2,ATP10B,NKAIN2,VAMP1,CAMTA1,SMG6,VWA3A,SYNE1,FAM200B,ICAM5,ERCC6L2,DAAM2,TPD52,TPM2,ZNF384,PDSS1,SSBP2,RPL7L1,TBC1D15,PLPPR5,MEIS3,EMSY,CADM2,PRDM10,PAK5,LAS1L" MicroRNA hsa-miR-513b:PITA hsa-miR-513b:PITA_TOP PITA 3.45E-51 1.94E-47 1.12E-50 1.03E-49 101 323 "SORCS1,NLGN4X,FAM135A,APC,NCOA1,SYNJ1,BSN,TMEM257,C1orf52,CCPG1,NRXN3,PCYT1B,AKAP6,IGDCC3,CRMP1,CSNK1G3,FAM131B,GAPVD1,HDAC4,SPATA2,ZEB2,POM121,DLG3,DLX1,GRIN3A,RASGRP2,ERBB4,EZH1,CACNG3,TAOK3,AFF2,DACH2,TBR1,ZNF512,OGA,GABRG1,AHCYL1,ARFIP1,GFRA1,PCDH17,SPIN1,EML4,GRID1,KAT7,NEGR1,INSM1,ITGAV,SLC35G1,MARK1,MAT2A,NEXMIF,GPR85,CDK14,PDZRN4,MAPKAP1,PACSIN1,MED1,PPP3CA,CEP41,ARID4A,ZYG11B,SLC25A36,ZFHX4,NLGN4Y,PPP4R3A,CPEB4,RIMS1,TMCC1,MYT1L,SOX5,ZCCHC24,DOK5,MYCBP2,PEG10,CDK19,LRRC4,STAU1,SYN2,CAMTA1,TAL1,EHBP1,TCF4,TRIM2,NSD1,CRTC1,SIRT1,KAT6B,RBFOX2,FNDC5,SLC35A4,AMOT,CLIP2,ZIC2,ZIC3,SMARCAD1,EMSY,CADM2,GOPC,HNRNPA3,SOCS4,SENP7" MicroRNA hsa-miR-217:TargetScan hsa-miR-217 TargetScan 3.45E-51 1.94E-47 1.12E-50 1.03E-49 101 323 "CSMD2,ARID1A,RNF150,BEND6,INTS2,KCTD16,ANK3,CACHD1,CDK5R1,DST,DLGAP2,CHN2,CLU,QKI,NIPBL,CLOCK,RBM39,PLXNA4,RIMS2,DOCK4,ARHGAP32,LIN54,KIAA0087,PLEKHM1,MYEF2,G3BP2,CHRDL1,PDCD6IP,RCAN1,DYRK1A,ABCC9,EDIL3,HIPK3,FSD1L,ELAVL2,EPHA5,ATP8A1,FOXG1,FOXO3,DACH2,GAB1,RAPGEF6,FAXC,GBX2,PCDH17,PPARGC1A,GPM6A,PARD3B,GRIK2,PSIP1,FRMD5,KLF12,MIER3,AGFG1,ATCAY,C5orf24,LRRTM3,KCNB1,KIF2A,ARHGAP12,NCOA7,MEIS1,MXI1,LYRM9,NAP1L1,NCAM1,NEUROD1,NF1,CNOT4,NOVA1,PCDH8,PCMT1,ANLN,FTO,POLG,MED1,PROX1,CNNM2,FIGN,ROBO1,ACER3,RIMKLA,SATB1,SCN2A,ELMOD1,PPM1E,FBXO11,NLGN1,EPC1,GKAP1,NPAS3,ATMIN,RPGRIP1L,ASXL3,AMOT,REEP1,EML6,HNRNPA3,CERS6,JMJD1C,FXR1" MicroRNA hsa-miR-4327:mirSVR_highEffct hsa-miR-4327:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.50E-51 1.97E-47 1.14E-50 1.05E-49 136 587 "DPY19L2P4,AGT,APC,ARNTL,EIF4G3,ATP2B1,DPY19L3,BACH1,KSR1,CDK5R1,SYNJ1,CACNA1B,VSTM2A,CDC42,SYNPR,ABI3BP,CNRIP1,CHD1L,ABCG1,RGS6,MICAL2,ERC2,PUM1,GPSM1,EARS2,DNAJC6,MYEF2,SV2B,CHRDL1,DTNA,EBF1,SNX29,EFNA3,YAF2,GOLGA7,RGS17,EMX2,ADGRV1,EZH1,RACK1,TESK2,SEC24B,POLR1B,BAIAP2,IP6K2,SLC37A3,AKAP3,STAG2,GABRA1,ADAM28,SPIN1,KDM2B,WDFY3-AS2,CNTRL,GRIA4,LINC01102,KCNN2,IPO5,AFDN,MXI1,MYO6,PABPC1L2A,NCAM1,NF1,NTRK2,PAK3,PCSK5,GNG2,NOMO2,HMGCLL1,PRRX1,SDK2,ING3,PKN2,MAPK9,GRAMD1C,MDGA2,CNTLN,PTPRD,NKAIN1,PID1,GSTCD,ROBO2,ELP2,ABCA11P,TRAPPC13,SALL1,SCN2A,SCN3A,FAM19A1,SCG5,ITSN1,FNDC3A,CNKSR2,RCOR3,RIMS1,ZNF415,SNRPN,SOX2,RBM26,PBLD,PRRC2C,PLCB1,SYN2,COBL,SYT4,MTCL1,TBX15,VWA3A,CUX2,SYNE1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,RIMBP2,R3HDM1,LAT2,ZBTB38,STOX2,MPPE1,WNK2,SLC17A6,C12orf4,EPM2A,FAM13C,DOCK8,RTN4,CASC15,MSRB3,SLC4A10" MicroRNA hsa-miR-1207-3p:mirSVR_highEffct hsa-miR-1207-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.67E-51 2.06E-47 1.19E-50 1.10E-49 146 672 "ASPHD1,TKTL1,CSMD3,SORCS1,AP2A2,CC2D2A,PLA2G6,TAOK1,ARHGAP20,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,BCAS1,AQP6,ASPA,BRINP2,NCOA1,DDX3Y,ATP2B3,NOL4,SEC11C,DCAF5,ARHGEF7,DDR1,MAP7,INA,ZMYM4,TIGD7,TJP2,LETMD1,AHCTF1,SEC31B,SNCAIP,SEC24C,MICAL2,PHF14,NRSN1,ST18,GPRASP1,ARHGAP24,DCAF8,IST1,RABGAP1L,RAB39B,OLIG1,FAM135B,EDNRB,OPTN,EFNB3,PHF20L1,MBNL2,MRVI1,FDFT1,GORAB,GTF2IRD2,BAIAP2,RGPD5,PSD2,NBEA,GALC,SRCAP,CRCP,GLI2,GLUL,MAP7D2,GNAS,DIPK1C,PRLHR,RAPGEF1,GRIA4,GRIN2C,IRAK3,FRMD3,CELF5,ZNF678,JAK1,CLVS2,KCNMA1,MAOB,AQP11,MOV10,NELL1,SMIM11A,P2RX7,ETFRF1,PDE4D,PIK3C2A,PIK3R1,JAKMIP1,SH3KBP1,PTPA,EPDR1,SIDT1,GON4L,PID1,SLC25A48,RAD51D,ARID4A,DBX2,MORC4,RLBP1,RPS20,TMEM156,AMER2,SCN2A,SCN3A,SGK1,PAAF1,EFHD1,IFT122,ANKRD36,NMNAT2,ZNF423,ZC3H13,C11orf87,ZSCAN29,STX1A,SULF2,GANAB,ANKRD28,ANO4,CUX2,TCF7,TCF7L2,TPCN2,AZIN2,ARHGAP9,ITGB3BP,AP4E1,SLC44A1,BHLHB9,TP53BP2,TPM1,PRMT8,CLHC1,PLEKHH2,CLDND1,RICTOR,CFAP298,CA10,EMSY,PCBP4,MPPE1,PARP11,CASC15,ZNF248,SLC4A10" MicroRNA hsa-miR-4267:mirSVR_highEffct hsa-miR-4267:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.06E-51 2.28E-47 1.31E-50 1.21E-49 137 596 "ABCF1,KCNH8,ACADM,AXIN2,UNC5A,SNX32,AGT,SEMA6A,GPRASP2,SUGT1P4-STRA6LP-CCDC180,APBB1,ASGR1,NUMB,ADAM15,ADGRB2,BARD1,CFLAR,CALB2,KALRN,NGB,TRIM41,CHGA,RAB33A,IGFBP7-AS1,CNR1,SLC4A8,SMARCAL1,CHD1L,SEC24C,FEZ2,ARHGEF10,PITPNM3,ZSCAN23,IST1,ZEB2,SMG7,SGSM2,TOM1,SGK2,SRARP,STRADA,DCTN2,UFM1,STAU2,ZNF512,ZMYND11,RAPGEF6,KIAA1841,BRD8,ZNF276,MSL3,ZNF782,PSRC1,CECR2,RAPGEF4,SOX21,RNFT2,GYG1,ACOT7,HNF4G,CPT1C,C5orf24,IGSF1,KCNC2,KCNK2,KIF5A,MAG,MEST,SCAMP5,MSR1,DDX25,MXI1,NFE2L2,HCN1,TREM2,PIRT,PDGFRA,OLA1,A2ML1,ST8SIA5,MED1,MINDY2,CRLS1,PRKCZ,MAPK3,MDGA2,TMEM260,PTPRO,FAM66C,BSDC1,ZYG11B,RFX4,DCUN1D2,CARF,TMEM206,PCMTD2,LGR4,ABCA11P,HSD11B1L,TRIM46,TRA2B,ITSN1,ZNF365,FAM81A,PEX26,DHX30,SIRT2,ELMO2,ZNF423,SPTB,SRPK2,ITPRID2,CEP68,VAMP1,PLCB1,DNMBP,ANO4,SATB2,TCF7,SZT2,DOCK9,LEFTY2,AP4E1,RIMBP2,TPM1,TMPRSS5,TSN,HSPBP1,RPL7L1,PCDH20,FMN2,FSTL5,URM1,PPP1R3F,NELFE,UBE3B,CASC15" MicroRNA hsa-miR-940:PITA hsa-miR-940:PITA_TOP PITA 4.28E-51 2.41E-47 1.39E-50 1.28E-49 94 278 "SDE2,XKR4,SLC12A5,UNC5A,ZNF608,PCDH19,DOC2A,PITPNM2,ANK1,MARK4,EIF4G3,N4BP2L1,CAMK2B,EVI5L,CFL2,DLGAP3,NRXN2,PICK1,SLC4A7,ZNF385A,PNKD,HAPLN1,CS,SIPA1L1,DCAF8,SRGAP3,SGSM2,DLG2,DNM1,ABCC5,EDIL3,ST8SIA3,APH1A,EGR3,RASGRP2,PRMT5,HPCAL4,BRSK1,JPH4,CPLX2,STMN2,LINGO1,BACH2,IGF1,IBA57,KCNA1,KCND2,KCNMA1,NCOA7,CHIC1,MEF2C,MOBP,CCDC80,PBX1,PDE2A,TRHDE,SCHIP1,RETREG2,EPB41L4B,POU3F2,MED1,MAPK10,PTK2,FAM120C,TMEM145,MORC4,SETD5,CYB561D1,ATXN1,SCN2B,ELMOD1,PPP4R3A,SORCS3,RCOR3,TMCC1,KIF21B,NMNAT2,PEG10,FAM168A,ZC3H4,VAMP1,ASTN2,CAMSAP2,PSD3,SIRT1,ZMAT3,HEY1,CBX5,TPM3,TRPS1,TUB,CADM2,GAL3ST3,VANGL2" MicroRNA hsa-miR-557:PITA hsa-miR-557:PITA_TOP PITA 4.64E-51 2.61E-47 1.50E-50 1.38E-49 98 304 "ABR,SORCS1,ADRA1D,NLGN4X,PCDH19,UNC79,AMPH,ARHGAP5,NCOA1,ATP2B2,B3GALT2,DOCK11,BCL7A,JAZF1,HAP1,CANX,TMEM257,ZMYM4,B4GALT6,BTF3L4,SLC4A7,MYRIP,DZIP3,ERC2,RIMS2,LONRF1,DLG2,DLG3,ABI1,DSCAM,DYRK1A,EDIL3,KMT5B,EIF4G2,EIF5,RGS17,ERBB4,MED12L,KHDRBS3,STAG2,GABRB3,B4GALNT1,GATM,AHDC1,PCDH17,DHRS4,GRIK2,BACH2,HNRNPK,AGFG1,ZIC5,KCNA1,KCND2,KCNJ3,MAP4,MBNL1,MEIS1,NEXMIF,NELL2,NEUROD1,NKX2-2,NPTX2,PCDH9,XRN1,CNTLN,PTPRD,USP47,REV3L,PCMTD2,FBXW7,SEMA6D,SCN3A,CHD9,DHX30,TET1,CPEB4,RCOR3,LMBRD1,SOX2,SP4,HECW1,PEG10,ZC3H4,ADAMTS17,ADGRL3,ANO4,TCF4,DMXL2,TRIM2,THRA,CSMD1,NR2C2,UBE3A,XRCC4,ZIC1,FMN2,PRDM2,PHTF2" MicroRNA hsa-miR-507:PITA hsa-miR-507:PITA_TOP PITA 4.64E-51 2.61E-47 1.50E-50 1.38E-49 98 304 "ABR,SORCS1,ADRA1D,NLGN4X,PCDH19,UNC79,AMPH,ARHGAP5,NCOA1,ATP2B2,B3GALT2,DOCK11,BCL7A,JAZF1,HAP1,CANX,TMEM257,ZMYM4,B4GALT6,BTF3L4,SLC4A7,MYRIP,DZIP3,ERC2,RIMS2,LONRF1,DLG2,DLG3,ABI1,DSCAM,DYRK1A,EDIL3,KMT5B,EIF4G2,EIF5,RGS17,ERBB4,MED12L,KHDRBS3,STAG2,GABRB3,B4GALNT1,GATM,AHDC1,PCDH17,DHRS4,GRIK2,BACH2,HNRNPK,AGFG1,ZIC5,KCNA1,KCND2,KCNJ3,MAP4,MBNL1,MEIS1,NEXMIF,NELL2,NEUROD1,NKX2-2,NPTX2,PCDH9,XRN1,CNTLN,PTPRD,USP47,REV3L,PCMTD2,FBXW7,SEMA6D,SCN3A,CHD9,DHX30,TET1,CPEB4,RCOR3,LMBRD1,SOX2,SP4,HECW1,PEG10,ZC3H4,ADAMTS17,ADGRL3,ANO4,TCF4,DMXL2,TRIM2,THRA,CSMD1,NR2C2,UBE3A,XRCC4,ZIC1,FMN2,PRDM2,PHTF2" MicroRNA hsa-miR-769-3p:mirSVR_highEffct hsa-miR-769-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.17E-51 2.90E-47 1.67E-50 1.54E-49 124 492 "KIAA1211,BEND6,OLMALINC,ADGRF5,AMT,PLA2G4C,ATP2B1,CFLAR,ZNF501,CLDN10,KRIT1,LGI1,SYNPR,KMT2C,SUMF2,FAM171B,ANKRD44,SNCAIP,GPRASP1,FRMPD4,ARMCX4,JAKMIP2,ELMO1,HP1BP3,EXOG,GRIN3A,DMTF1,FARSB,EDN1,EDN3,FCF1,APH1A,RASA4,GOLGA7,DCTN4,ENO2,RCAN2,SRRM1,F8,FABP7,TAOK3,FDFT1,KAT8,POLK,GABRG2,AHCYL1,B4GALNT1,GAP43,GLS,MAP7D2,GRIA1,GRIA4,RFFL,GRM7,FAM19A2,FAM222A,FRMD3,HLF,HNF4G,HNMT,LRRC75A,LRRC25,KCNJ3,KCNMA1,MEIS2,SRSF12,MEST,MYO7A,VWA2,CNOT4,NOVA1,NPTX1,PCSK5,PCDH18,RASGEF1B,HYDIN,PTPRE,TTC13,OXR1,HKR1,SEC61A2,PBRM1,C12orf49,ADAL,FAM182A,SCN8A,SEC14L1,CCDC92,WDR47,KBTBD4,SMARCD3,INTS9,SMARCE1,RCOR3,LIMCH1,UNC80,SOX2,KDM4C,RAP1GAP2,SPART,POGZ,INKA2,TACR1,SATB2,RNF175,AP4E1,HEY2,TNFRSF1B,PIK3R5,CDK20,SYNPO2,TUBB1,UBE2H,PITPNB,VLDLR,WIPF1,ZNF708,MICU3,ZNF154,REEP1,INTS3,CA10,STOX2,NHSL1" MicroRNA hsa-miR-603:Functional MTI Functional MTI miRTarbase 5.51E-51 3.09E-47 1.78E-50 1.64E-49 126 508 "CSMD2,ADCYAP1R1,ESYT2,MTA3,KCTD16,TAOK1,LRFN1,ANK3,TNRC6C,DPY19L3,BACH1,JAZF1,BSN,CA8,CDH2,TBRG4,CFL2,B4GALT6,TBPL1,CRY2,ANKRD44,MYADM,LONRF1,RIMS3,SPOCK2,DBT,MED24,KLHL3,SV2B,EGR3,PLXNC1,SORBS3,EIF5,C8orf37,TUBD1,CHST15,SGIP1,AFF2,ZBED3,MPP6,HRASLS5,SYT17,SEPT9,GCK,SRCAP,PPARGC1A,RAPGEF1,PARD3B,CACFD1,NR3C1,GSN,IL1RAPL1,FICD,ATOH8,HLF,IGF1,SCIN,IL6ST,KCNA4,KCNB1,KCNJ3,KLHL23,KCNK1,KIF5C,SYTL4,FGFBP3,MOBP,NEXMIF,P2RY1,ZDHHC22,KCNK10,TMOD2,PIK3R1,PLCL1,FAT3,CRLS1,SNRK,UHRF1BP1,RDX,ZMAT4,GTDC1,C12orf49,ATAT1,SBF1,CSRNP3,DRAXIN,SLC12A2,SLC22A4,ZFP1,KIF13A,FAM126B,WDTC1,TRERF1,UNC5B,SS18,AJAP1,NECAB1,SYT5,TPCN2,GPRIN3,SIK3,HHIP,SLC44A1,GALNT17,NACC2,DDHD1,BHLHB9,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,SF1,NDRG4,CRB2,ZXDA,LRP8,ADAMTS9,HPS4,WNK3,MVB12B,FAM198A,SPATA13" MicroRNA hsa-miR-196b*:mirSVR_lowEffct hsa-miR-196b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.55E-51 3.12E-47 1.79E-50 1.65E-49 130 540 "NDRG3,ARHGAP20,GPRASP2,MRTFA,PHF12,GPAM,DGKD,ALS2,CACHD1,VAT1L,CDK10,CASK,RNF182,RIPK1,TTLL9,BACH1,CDK5R1,GYG2,PTBP2,MYOM2,SRSF11,B4GALT6,JAM2,NRXN3,CLU,NIPBL,AKAP6,SUMF2,BTF3L4,MAGED1,ABI3BP,CREM,CSF2RA,ARHGEF10,OSBPL3,ST18,RUBCN,KCTD8,GIT2,DGCR5,SV2B,RABGAP1L,ABI1,DTNA,DNAJB6,ABCC5,AASDH,HIPK3,FRY,PHF20L1,GOLGA7,GPHN,EPS8,FGFR1,FHL1,SYNCRIP,FLNC,SLC37A3,FAM49B,CSPG5,GABRA2,NEK6,TCERG1,GLYR1,DIDO1,GRM8,AP4S1,HSF2,CELF5,LRRCC1,KCNA6,VWA5A,SYT9,LDLRAD3,IDNK,DNHD1,GPR88,P2RX7,PAH,SNTG1,SERPINI1,STRN3,PCDHB17P,PRPH,MDGA2,TMEM260,PTPRO,RASGRF2,REV3L,ROBO2,SNX22,TRA2B,SCG5,SH3GL3,DOCK10,EFHD1,LGI3,SNAP25,MYO16,NPAS3,C11orf87,ADHFE1,KLHL7,PRRC2C,CAMTA1,DNMBP,CAMSAP2,ZEB1,DOCK9,PCDHB7,PUM2,RNF216P1,ZFPM2,CRB1,SPX,SLC44A1,ARL10,TRO,CADM1,LAT2,CLDND1,XRCC4,PRDM10,TUBA1A,PCDH15,KCNAB1,DOCK8,SMIM8,CASC15,SNX14" MicroRNA hsa-miR-877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-51 3.96E-47 2.27E-50 2.09E-49 138 607 "ABR,ACLY,EMILIN3,ARID1A,SLC25A25,GRAMD1B,AP2A2,ZNF687,ANK1,ANK2,TNRC6C,ARHGDIA,STK33,ZBTB10,CCAR2,ATP2B3,AP1M1,NIPA1,CANX,SPAG9,RUNX1T1,AIFM1,SCARB1,ARHGEF2,LRRFIP1,DIS3L,COPB2,SYNPR,SLC22A6,CLTC,IGLON5,SH2B1,AKAP12,RGS6,APPL1,TCAF1,DCAF8,FRMPD4,KIAA0586,IP6K1,CTIF,DBN1,SPATA2,RUSC2,POM121,RCAN1,ECM2,EPB41,SLC43A2,REEP2,TBC1D16,TUBA1B,SCML2,DLC1,SYNCRIP,ANKFY1,NELFCD,HHIPL1,DKK3,BRPF3,RAPGEF6,FAXC,SRCAP,ARFIP1,TCERG1,GLYR1,GLUL,ZNF638,CBX1,HTATSF1,PRRC2B,GPD2,EML4,TUBA1C,RAPGEF1,GRM8,HMGB1,HNRNPK,IPO5,CYP27C1,MBNL1,NACA,NAP1L1,NODAL,NUCB1,PBX1,PCMT1,GNG2,OLA1,SSH1,PKM,KCTD15,FAM216A,POLG,PRKCB,PIGG,EML5,RAB5B,PLEKHB2,PBRM1,SETD5,MYH14,TMEM156,SBF1,ATXN1,SCAF8,ZFP30,MYO18A,FNDC3A,URGCP,KANSL3,SLC6A8,SLC20A2,LIMCH1,ZHX3,EPB41L3,ERBIN,PRRC2C,VAMP1,TMEM151B,TP53BP2,TRPC3,TTC3,HIRA,CADM1,RPL7L1,BCL2L13,VAV2,ZBTB38,AMZ1,WNK1,SLC38A1,TUBA1A,FIP1L1,ITM2C,MVB12B,KAT6A,NHSL1" MicroRNA hsa-miR-4317:mirSVR_highEffct hsa-miR-4317:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.47E-51 4.76E-47 2.73E-50 2.52E-49 131 550 "ABAT,KCNH8,ACADM,KLHL32,ALCAM,UNC79,MAP4K3,UPRT,RASL11B,DDX3Y,ATP2B1,RNF182,N4BP2L1,ADAM23,BACH1,CFLAR,ARHGEF7,FUBP1,SGCE,CAMK2G,CBS,RGN,TIGD7,CCPG1,MFSD4A,SLC35F1,GDA,LRIG1,ATRNL1,APPL1,PHF14,ST18,ARHGAP24,DGKB,FBXL5,KIAA0753,DMTF1,DTNA,SYT15,KLHL5,AASS,ELAVL2,SRRM1,DUSP27,F5,KIAA1109,OLFM1,FOXM1,ATP13A4,ANKFY1,PDLIM5,DACH2,STAU2,ZNF512,PPARGC1A,RAB30,PCDH11X,FUT10,GRIA1,GRIA2,GRIA4,PLCD4,ATE1,GRM8,LINC01102,TCEAL6,SHISA6,HTR5A,MYLK2,BRINP3,KCNC2,FGFBP3,SYT9,MSRA,LYRM9,MYO9A,FXYD7,CNTN3,PDE4D,GNG2,CAMKV,PIK3R1,HMGCLL1,PMP22,TRHDE,RETREG2,PPM1B,PPP3CA,SYTL2,PTPRO,TMEM231,MARCH1,OXR1,SLC6A15,FIGN,ALG9,ELP2,ASIC4,SH3GL2,ARX,ABLIM3,SLC8A1,RAB3GAP1,SLC12A2,ATF7IP,SLCO1A2,SORCS3,TSPYL2,NKAIN2,SULF2,SYN2,TAC1,MTCL1,CAMTA1,VWA3A,ACSL6,PUM2,TEX15,SIRT1,AP4E1,RIMBP2,AMACR,DNAJC12,TCEAL7,PMEPA1,MAP3K12,PCDH15,FIP1L1,WNK3,DNAH10,FRMD6" MicroRNA hsa-miR-2114:mirSVR_highEffct hsa-miR-2114:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.84E-51 4.97E-47 2.85E-50 2.62E-49 129 534 "SERPINA3,CSMD3,NDRG3,ADD1,PWWP2A,RTL9,OGT,STK33,ASPH,ZSCAN18,BCL2L2,FGF17,BID,GPC2,CACNB2,KALRN,CERS5,CFL2,IGFBP7-AS1,PPT2,CNRIP1,CHD1L,SNCAIP,ARHGEF10,SOCS5,CTNND1,CYBB,HDAC9,ARHGAP32,DCAF8,CENPL,DBI,DNAJC6,ZEB2,SEMA3D,PHF20L1,EPB41L2,EFS,EXTL1,F3,TESK2,POLR1B,FGF11,ANKFY1,TACC2,PDLIM5,NSG1,OGA,MEGF10,GALNT15,DISC1,MYOZ2,SESN1,PPARGC1A,CECR2,GRB10,GRIA4,MFSD2A,LINC01551,HSF2,SOWAHA,IL6ST,ZNF678,STXBP5,CAMK2N2,STMN1,NCOA7,LSS,ZFYVE27,MBNL1,LDLRAD3,MEF2C,AFDN,RSPO2,MXI1,SFR1,NINJ2,OCRL,PDYN,GPR85,PRRX1,SLC36A4,CEP41,HYDIN,SAMD9,C1orf109,RAB3IL1,RAD52,RAP1GDS1,DBX2,GTDC1,RIC8B,RPRD1A,ROBO2,YY1AP1,RPE65,RMI1,FERMT1,FAM81A,RAB3GAP1,ATF7IP,NAXD,SMARCC2,WDTC1,KIF1B,MPRIP,NEK4,RGL1,ANKRD28,C12orf76,MCF2L,ZEB1,TRIM2,WDR7,PCDHB6,ARHGAP9,AP4E1,TPD52L2,TPM3,ELP5,SSBP2,RPL7L1,UCHL1,KCNT2,ZNF154,SPIRE1,PRDM2,VPS35L,MPPE1" MicroRNA hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA_TOP PITA 1.03E-50 5.76E-47 3.30E-50 3.04E-49 103 340 "PCDH19,HACE1,APBA2,CACHD1,ARHGAP5,B3GALT2,NOL4,SYNJ1,FUBP1,JAZF1,NIPA1,DGKI,MAGI1,CFL2,B4GALT6,QKI,PCYT1B,CS,SLITRK5,ERC2,RIMS2,RIMS3,DCC,DNAJC6,DYRK1A,RBM12,MBNL2,ELAVL4,PCOLCE2,PAN3,ERBB4,ZIC4,FGF12,ATP6V1H,FUT9,BRPF3,PCDH17,GPM6B,NR3C1,RNF165,HAS2,HES5,LRRTM3,KCND2,KTN1,MAN2A2,MBNL1,MDM4,LRP1B,MEF2C,KITLG,MN1,NEXMIF,NAP1L1,NFIX,HCN1,XRN1,SMOX,PLP1,PLXNB1,NXPH1,POU3F2,DRAM2,PPP2R5E,PPP3CB,MTMR10,PTPRG,TMEM145,RDX,ROBO2,SCN3A,HSPA4L,KIF21A,ST6GAL1,CCDC88A,RCOR3,MYT1L,SOX11,ZBTB43,NFASC,TAB2,POGZ,RGL1,STXBP1,GSE1,ZC3H4,VPS13A,TAC3,CAMTA1,CAMSAP2,SATB2,CUX2,RPGRIP1L,TJP1,UBE3A,MICU3,ZBTB38,SYNC,LRP8,PARP6,TMEM178A,WIPF2,FRMD6" MicroRNA hsa-miR-184:mirSVR_lowEffct hsa-miR-184:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.04E-50 5.82E-47 3.33E-50 3.07E-49 117 441 "ADD1,MTUS1,SNX32,AK2,HFM1,GOLGA7B,AMPD2,LRCH2,PKP4,ARHGDIA,DYNLL1,ALDH4A1,ADGRB2,KSR1,ARHGEF7,ARHGEF2,CDC25B,CDC42,DCLK1,PLEKHB1,TPP1,IGLON5,NCOR2,CSF1,MICAL2,KIAA0040,ARHGAP32,RASSF2,SIRPA,PITPNC1,ZBTB24,POM121,DLX1,TRAPPC9,ABCC9,EDIL3,CNNM1,TMTC1,RBM12,EIF4G1,PLEKHA1,TNK2,EPB41L1,EZH1,F5,FGFR1,AGAP2,EVL,ZBED3,CHL1,GLS,MSL3,POLL,LOXL3,GNAO1,GPD2,ATF7,KIF3A,LINGO1,SLC2A6,ATXN2L,SHISA6,SCRT2,LMO1,MAP6,SCAMP5,PTOV1,FXYD7,ALDH1L2,ZDHHC22,PDGFRA,TNPO2,POU3F2,PRKCB,FAM120C,ATG16L1,ZNF493,DPF2,UBR7,LGI2,BAALC,FAM192A,SAFB,KIF21A,SLC6A8,SLC6A9,TMEM132D,NAXD,LIMCH1,WDTC1,SOX1,TRERF1,KIF21B,SPTAN1,DDN,EPB41L3,STXBP1,ZFR2,VAMP1,MTCL1,CAMTA1,EXOC7,SATB2,TPCN2,CYB561A3,DICER1-AS1,CRB1,THRA,TNS1,TPM2,ZMYND8,KLC2,SPHK2,GDPD5,FAM47E,NLRP3,PIANP" MicroRNA hsa-miR-129*:mirSVR_highEffct hsa-miR-129*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.09E-50 6.11E-47 3.50E-50 3.22E-49 130 543 "ACADM,ACLY,XKR4,NDRG2,FMNL2,KIDINS220,KLHL13,HFM1,LRRC7,CACHD1,NAE1,BTK,JAZF1,PTBP2,USP6,TMEM257,DGKI,HECTD1,COL9A1,LETMD1,ABI3BP,COX4I1,RBM39,VAC14-AS1,CTNND1,DOCK4,TOMM20,SPATA2,RHOBTB1,SACS,GOLT1B,E2F5,FAM135B,EDNRB,PHF20L1,RCAN2,RTN3,F5,ZSCAN30,MED12L,POLK,CAP2,ANKFY1,NOP56,AKAP3,NPTN,GABRA1,JPH4,DISC1,CECR2,GRIK4,GRIN2D,PRDM5,FRMD3,DOCK7,LIX1,DIPK1A,KHK,KIF5A,PAXBP1,HECTD2,PIK3AP1,IL17D,MMP16,MYO9A,NINJ2,GPR137C,GLIPR1L2,PDYN,CYTL1,HMGCLL1,TRHDE,PKIA,PKN2,GDPD2,MTMR10,SPDL1,ERI2,RFX3,RGS12,CCDC82,SUGCT,CCDC102B,TMEM100,BAALC,TCP11L1,MEG3,HUNK,RTKN,RYR3,NCBP3,LINC00461,CASC3,FRMPD1,ABLIM3,DHX30,SLC8A3,SLC9A5,RIMS1,SON,BDP1,ATP10B,COLGALT2,SS18,ERBIN,GSE1,SYT4,ANKRD12,CAMSAP2,TMEM136,TCF7,SLC19A3,FRYL,PMS2CL,CRB1,TIAM1,HEY1,TNR,TPD52,TRIO,TRO,RPL7L1,FAM155A,FLRT2,PRDM2,PRDM8,PLSCR4,PHTF2,SSPN,LAS1L" MicroRNA "ATGTACA,MIR-493:MSigDB" "ATGTACA,MIR-493:MSigDB" MSigDB 1.31E-50 7.38E-47 4.22E-50 3.89E-49 96 294 "ARID1A,FMNL2,UNC5A,PCDH19,OSBPL6,SRPX,PHF12,MADD,TMEFF1,ARHGAP5,NCOA1,RASL11B,ATP2A2,BCL7A,CAPN3,USP6,DGKI,CDH2,SRSF11,NRXN3,LRIG1,CTNND1,CTNND2,RIMS3,SV2B,AK5,DLG2,E2F6,TMTC1,EFNA3,RBM12,PHF20L1,MBNL2,EYA1,TAOK3,FGF13,PSD2,NBEA,USP21,GAB1,GABRA1,GABRA5,GABRG2,GAD1,AHDC1,GRM5,SOX21,ZNF385B,LRRTM3,KCNMA1,MARK1,MEF2C,GIT1,PDE4D,PDPK1,NLGN3,PIK3R1,PCDH18,PMP22,LRP12,NXPH1,PPP2R2C,PPP2R5C,PPP3CB,SLC22A23,RBBP6,FIGN,ZNF532,RPE,SALL1,FHOD3,NLGN1,MAST1,SORCS3,MBD5,PDZRN3,SP4,KIF1B,SRPK2,LARP4,SS18,ANKRD28,ADGRL3,ANO4,CLASP1,SYNE1,DOCK9,PUM2,TJP1,TRPS1,EIF4ENIF1,UBE3A,ZIC1,ZIC2,PLPPR5,NAV2" MicroRNA hsa-miR-134:mirSVR_highEffct hsa-miR-134:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.34E-50 7.54E-47 4.31E-50 3.97E-49 149 705 "KCNH8,NBAT1,SORCS1,WDR35,AMPH,AMT,SUGT1P4-STRA6LP-CCDC180,EPB41L5,CACHD1,NUMB,ATP6V0A1,BACH1,MPDZ,MTMR2,CACNA1D,CARS,RUNX1T1,SLC16A4,P2RX6,MAGI1,CHN2,JAM2,FAM19A5,MAP4K4,ARHGEF6,MFSD4A,CPS1,FAM171B,ANKRD44,SNCAIP,KIAA0040,NRSN1,ARMCX2,CEP170,AK5,DNAH9,PDCD6IP,DSCAM,GNE,EDN1,EGFR,EIF1,VPS13B,TMEM74,EXTL2,TAOK3,KIAA1109,FOXG1,ZNF605,DOT1L,GABBR1,ILDR2,BRPF3,ERAP1,MSTN,PCDH11X,CBX1,GNAL,GNAO1,MCHR1,EML4,CECR2,GRIK2,GYG1,MAEL,HAS2,HNMT,HSP90AA1,KCNK2,KCNMA1,KCNQ3,KPNA5,MAT2A,MBNL1,LRP1B,MMP16,CTNNA3,NFE2L2,NRCAM,NRDC,NTRK2,LOC100128398,ETFRF1,PIK3C2A,A2ML1,XRN1,PLCB2,CEP41,PRKCG,PTPRB,SLC25A41,SUSD4,CRTAC1,SEC61A2,ELP2,PCMTD2,RPL15,ADAL,WLS,ZNF354C,SCN2A,TNFRSF19,ITSN1,MAGI3,CCDC92,ST3GAL3,SLA,RAB3GAP1,SLC8A3,SLC14A1,GKAP1,SMARCE1,RIMS1,ZNF415,SNRPN,ZNF423,SPTAN1,KIF1B,NFASC,CLSTN2,KANK1,AJAP1,ACSBG1,VPS13A,ANO4,NSD1,SIK3,ZFPM2,TMEM9,KAT6B,ZMYND8,PPIL6,SSBP2,ZKSCAN5,CADM1,SLAIN1,BEST1,WIPF1,ZNF711,ZNF28,TRIM9,PLPP4,MKRN3,FSTL5,SLC30A4,MFF,CADM2,TRAM2-AS1,KLHDC1" MicroRNA hsa-miR-326:TargetScan hsa-miR-326 TargetScan 1.43E-50 8.03E-47 4.59E-50 4.23E-49 107 369 "RALGAPA1,C3orf14,EMILIN3,ELFN2,CASKIN1,ALAD,GOLGA7B,KIF6,DYNLL1,ATP2B2,ATP6V1G2,BCL2L2,BTRC,DGKI,DLGAP2,CHRM1,RAB3C,DLGAP3,CLCN4,CLU,QKI,IGLON5,NSL1,CRY2,NCAN,SDC3,KIAA0513,DGKG,AIF1L,CHRDL1,DLG3,PDCD6IP,DTNB,HEYL,EFNA3,CELSR3,ABI2,EGR3,EIF1,EPB41L1,ANKRD13B,ERBB4,APC2,CORO2B,FCGR3A,FGF1,FGF11,FGFR1,ANKFY1,GPR153,NEURL4,GAB1,CHL1,CPLX2,KIAA1958,GPD2,GRIN1,PADI2,SCIN,LRRTM1,KCNB1,KCNC1,KCND3,KCNH1,KCNJ5,MEST,JAKMIP3,SAMD14,MYO9A,PABPC1L2A,NFIX,NOVA2,NRGN,KCNK10,PALM,PDE1B,PLEC,PLXNB1,SDK2,POLR2F,PPP3CB,PKIA,MAPK4,BCAS3,NKAIN1,IQSEC3,BSDC1,DPF2,KLHDC8A,KCNIP2,ITSN1,FNDC3A,BTBD3,SCMH1,MBD5,FAIM2,FAM126B,ERC1,NPAS3,FAM168A,RHBDL3,AHCYL2,CDH22,RBFOX2,KCNK12,ELFN1,PPP1R3F" MicroRNA hsa-miR-330-5p:TargetScan hsa-miR-330-5p TargetScan 1.43E-50 8.03E-47 4.59E-50 4.23E-49 107 369 "RALGAPA1,C3orf14,EMILIN3,ELFN2,CASKIN1,ALAD,GOLGA7B,KIF6,DYNLL1,ATP2B2,ATP6V1G2,BCL2L2,BTRC,DGKI,DLGAP2,CHRM1,RAB3C,DLGAP3,CLCN4,CLU,QKI,IGLON5,NSL1,CRY2,NCAN,SDC3,KIAA0513,DGKG,AIF1L,CHRDL1,DLG3,PDCD6IP,DTNB,HEYL,EFNA3,CELSR3,ABI2,EGR3,EIF1,EPB41L1,ANKRD13B,ERBB4,APC2,CORO2B,FCGR3A,FGF1,FGF11,FGFR1,ANKFY1,GPR153,NEURL4,GAB1,CHL1,CPLX2,KIAA1958,GPD2,GRIN1,PADI2,SCIN,LRRTM1,KCNB1,KCNC1,KCND3,KCNH1,KCNJ5,MEST,JAKMIP3,SAMD14,MYO9A,PABPC1L2A,NFIX,NOVA2,NRGN,KCNK10,PALM,PDE1B,PLEC,PLXNB1,SDK2,POLR2F,PPP3CB,PKIA,MAPK4,BCAS3,NKAIN1,IQSEC3,BSDC1,DPF2,KLHDC8A,KCNIP2,ITSN1,FNDC3A,BTBD3,SCMH1,MBD5,FAIM2,FAM126B,ERC1,NPAS3,FAM168A,RHBDL3,AHCYL2,CDH22,RBFOX2,KCNK12,ELFN1,PPP1R3F" MicroRNA hsa-miR-27b*:mirSVR_highEffct hsa-miR-27b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.63E-50 9.15E-47 5.23E-50 4.81E-49 140 628 "ABAT,FMNL2,CCDC85A,DPY19L2P4,INTS2,HECW2,TAOK1,OGT,ANK2,USP28,PKP4,GPAM,SHROOM2,MIER1,RNF182,ZNF501,SRSF11,CNR1,CNTFR,AKAP7,AKAP5,TBPL1,PREPL,RBM39,OSBPL3,APPL1,PHF14,NRSN1,FGFR1OP2,ZEB2,CEP170,CDON,ACOT8,DNM1L,FAM135B,OPTN,YAF2,PHF20L1,EIF4G1,ELAVL2,F8,ST3GAL6,BAIAP2,EFCAB2,POMT1,TPK1,STAU2,PHYHIPL,SULT1C4,GLUL,GPD2,RAPGEF4,GRIA4,NR3C1,FAM19A2,BVES,ZHX1,OPALIN,CELF5,LRRCC1,KCNK1,LIMS1,SRSF12,MRPL42,CTNNA3,MTTP,NAP1L1,NELL2,NF1,SLCO1C1,NFE2L2,NRCAM,NUMA1,PDE3A,PENK,SLC25A23,LRP12,TATDN3,RASGEF1B,MAPK10,PRPSAP2,GDPD1,SAMD9,SIDT1,PTK2,TMEM260,PTPRG,SH3TC2,RGS4,RPRD1A,ZNF532,TMLHE,ROBO2,TMEM206,PRR5L,ADAL,ZNF568,MIR124-2HG,CSRNP3,SLC30A10,BTBD3,SIRT2,SLC12A2,NAXD,SMARCE1,INAVA,LIMCH1,USP33,SPTB,SRPK2,MPRIP,ZSCAN29,DIP2A,KANK1,PLCB1,ANKRD28,CAMSAP2,CNTN2,TCF7L2,PCDHB7,HIF3A,ITGB3BP,TGFBR3,TIAM1,TIE1,NR2E1,C5orf64,SYNPO2,TRPS1,UBTF,MTCH1,VSNL1,ZNF781,CLDND1,ZNF28,ZNF189,WNK3,NUP214,NETO2,SENP7" MicroRNA hsa-miR-1229:mirSVR_highEffct hsa-miR-1229:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.79E-50 1.01E-46 5.74E-50 5.29E-49 141 637 "EMILIN3,GALNT13,WDR35,AK2,DPP10,APC,PPP4R4,SPTBN4,ARNTL,ASCL1,MARCH3,NUMB,DDR1,CACNB4,KALRN,RUNX1T1,CBR1,CASC2,LSMEM2,KIAA1549L,CLCN4,TJP2,QKI,ZFP28,SEC31B,CTH,DCAF8,SPOCK2,MFAP3L,FBXL5,CHRDL1,DRD1,RCAN1,E2F5,EBF1,KMT5B,EIF4G2,EXTL1,SIRPB1,FAM198B,FDFT1,SEC24B,KIAA1109,SEC23B,ZCCHC17,OGA,CHL1,GABRG2,GAD1,ZNF559,WASHC2A,GHR,GNAS,PRLHR,GPR12,RFFL,FAM19A2,GYG1,TNFAIP8L3,CELF5,MATN2,MOBP,ZNF680,MRPL42,NELL1,CNOT4,SLC11A2,ZDHHC22,PDGFRA,DUSP26,PLCB2,PLCL1,ING3,SEPT4,NXPH1,PRKCG,PRKCZ,SNRK,CNTLN,PLPPR1,TMEM260,PTPRD,PEX2,RAD51D,ZNF493,ZFHX4,RORB,ZNF568,SAFB,SLC30A10,CASC3,ST3GAL3,ZNF365,SLC2A5,LRRC55,ZNF430,ARHGEF40,SLC12A2,ATF7IP,SPHKAP,NAXD,ZNF667,SMARCE1,SNAP25,SNCA,SOX5,ZCCHC24,KIF1B,DDN,POGZ,ZSCAN29,VPS13A,ANKRD12,TMEM136,ZEB1,GPRIN3,KHDC1,CRB1,ITGB3BP,AP4E1,TGFBR3,RBFOX2,WBP2,ANKRD20A2,CADM1,RPL7L1,UBE3A,AMOT,ZNF781,CLDND1,RICTOR,GUSBP1,ZIC3,ZNF19,PROCA1,EMSY,PRDM8,WIPF2,PDSS2,KAT6A,ADAMTSL3" MicroRNA hsa-miR-139-5p:TargetScan hsa-miR-139-5p TargetScan 1.99E-50 1.12E-46 6.37E-50 5.87E-49 99 315 "NDRG2,GALNT13,ADCYAP1R1,KCTD16,PCDH10,ANK1,LRCH2,ANK2,ATP2B2,SCAPER,MTMR2,CACNA2D1,CAMK2D,CANX,CBFA2T2,CDH8,CACNA2D2,QKI,DCC,JAKMIP2,DMD,DPP6,EBF1,PLXNC1,EIF4G2,ELAVL2,EIF1,MRVI1,MEX3B,FAM49B,GABRA1,GABRA3,GABRB1,PPARGC1A,GLI2,GNAL,GPR37,CECR2,GRM1,KIF3A,MIER3,ELOVL5,HMGCR,NEGR1,CDH20,KCNB1,KCND3,KLHL23,KIF5C,KTN1,LSAMP,MAP2,MBD1,MBNL1,MEIS2,NFIA,NPTX1,HCN1,PCDH9,PCSK5,PDE3A,PDE4A,PDE4D,KCTD15,PMP22,LRP12,SCHIP1,FAT3,NXPH1,LRRN3,RASGEF1B,MAPK8,MDGA2,PTPRD,RASGRF1,ARID4A,RORB,CSRNP3,ATXN1,LRFN5,SCN3A,SCN4B,ARX,CHD9,KIF13A,AJAP1,FAM168A,ATP11A,FBXL16,ASXL3,KAT6B,RBFOX2,CADM1,KLC2,NDRG4,DPYSL5,PRDM10,FZD3,KAT6A" MicroRNA hsa-miR-484:mirSVR_highEffct hsa-miR-484:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.19E-50 1.23E-46 6.99E-50 6.44E-49 134 579 "TTYH1,DGCR6,ACHE,ABHD6,C3orf14,ERMN,ADORA3,LRFN2,PCDH19,CC2D2A,FAM135A,ANK1,ARSE,DACT3,CAST,CDK11B,MAGI1,CLTA,COL9A2,ACBD5,SEC31B,CREM,ANKRD44,SNCAIP,CSF1,NCAN,FAM169A,RIMS2,DCAF4,RIPOR2,FRMPD4,PHF19,RHOBTB1,SV2B,RABGAP1L,DNM2,DPYSL2,SGK2,SEMA3D,EIF4G2,STARD3NL,EPHA5,EPHB1,ETV1,RTN3,TOMM40L,FGF1,SPSB4,FHL1,POLK,AP4B1,ABLIM2,GAP43,WASF3,NEU3,COPS8,GOLGB1,GRIA4,GRIN1,GRM1,GRM2,RNF165,MFSD2A,MAP4K5,GYG1,PADI2,NXPH2,DOCK7,SCIN,IL6R,KCND1,KIT,MAP2,MBD1,MOV10,PTOV1,SLC11A2,NUMA1,OGDH,RETREG1,PLP1,SMIM7,PLXNB3,NXPH1,PRKCG,PKN2,GRAMD1C,SAMD9,APTX,PSMD13,BDNF-AS,TMEM260,PTPRE,BSDC1,ZMAT4,TRIM68,REV3L,GTDC1,ARHGEF10L,GLDN,ABCA11P,SCP2,TRIM46,ST3GAL3,SLC6A1,SLC20A2,ZNF667,RIMS1,SNRPN,SOX5,ZCCHC24,MYCBP2,KDM4C,ST5,INKA2,TACR1,TBCEL,TBL1X,WASHC4,GPRIN3,CYB561A3,CRB1,TGFBR3,ENHO,TK2,NPL,FNDC5,DNAJC12,LGI4,PROCA1,UPF3A,STOX2,LMAN2L,PPP1R3F" MicroRNA hsa-miR-593*:mirSVR_highEffct hsa-miR-593*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.44E-50 1.37E-46 7.80E-50 7.19E-49 140 630 "AS3MT,METAP1D,FMNL2,ADCY5,ADCY6,GALNT13,AXIN2,PLEKHH1,PWWP2A,KIDINS220,KCTD16,AMPD3,OGT,LRCH2,UPRT,BCAS1,LGR5,ADGRB2,BTK,MMD2,CA8,CACNA1D,CALB2,TRIM41,CERS5,NUMBL,CLCN3,CLU,NIPBL,BTF3L4,HS3ST5,ANKRD44,SOCS5,UBXN2A,NOS1AP,IST1,SPOCK2,PABPC5,GIT2,SIRPA,ZEB2,HEPH,HP1BP3,FBXL5,SPOCK3,NTM,G3BP2,DTNA,DYRK1A,SNX29,EDNRA,FCF1,PHF20L1,EGFR,LPAR6,TMEM74,FDFT1,AGAP3,SEMA4D,UFM1,TPK1,ARFGAP2,CAMKK2,AP4B1,STAG2,NCKAP1,GDF9,RAB30,LOXL3,GNAO1,GRIA4,NR3C1,GRM1,GRM5,AP4S1,HNRNPK,SMAP1,TJAP1,KCNN3,PACRG,MARK1,SYT9,MMP16,ZNF92,NOS1,NPTX2,NUCB2,LOC100128398,PAH,PDE4B,PDYN,ZDHHC8,NALCN,PIK3C2A,ZNF655,PLCL1,PLEC,FTO,PMP22,EPB41L4B,GRAMD1C,SAMD9,PTPRB,ZSCAN2,GTDC1,RPRD1A,DCUN1D2,ROBO2,SEMA6D,SUPT20H,MYO18A,RUFY2,ELMO2,TET1,RCOR3,UNC80,DOP1A,KIF1B,NPAS3,ATP10B,CLASP2,STAU1,ADHFE1,ZFR2,SYNE2,CAMTA1,SYNE1,FAM200B,ZFPM2,SLC44A1,CSMD1,TRPS1,VLDLR,WIPF1,FMN2,MAP3K12,EMSY,MFF,PIANP,IFT88" MicroRNA "GTGCCAA,MIR-96:MSigDB" "GTGCCAA,MIR-96:MSigDB" MSigDB 2.55E-50 1.43E-46 8.16E-50 7.52E-49 94 283 "ABAT,XKR4,SLC25A25,ADCY6,SLC12A5,KCTD16,SEMA6A,ALK,OGT,LRCH2,VAT1L,BRINP2,DPY19L3,ADGRB3,JAZF1,CDK5R2,LDLRAD4,CACNB4,LDB2,EVI5L,MAGI1,DLGAP2,CACNA2D2,NRXN1,NIPBL,CNN3,CABP1,COL9A1,MYRIP,CDC42BPB,CSF1,LRIG1,RIMS4,CTNND1,HDAC9,ARHGAP24,TM9SF4,CEP170,PLPPR4,E2F5,PHF20L1,EIF5,FOXF2,FAM49B,FYN,BRPF3,B4GALNT1,GPM6A,GPM6B,RAPGEF4,GRID1,GRM1,ZHX1,BACH2,LAMP2,MITF,NOVA1,NPTX2,PRRX1,EPB41L4B,SH3KBP1,ATG16L1,BSDC1,RIC8B,ZFHX4,ATXN1,SOX6,TRIM46,ST3GAL3,SLC1A2,FAM81A,BTBD3,SLC6A9,CPEB4,SOX5,RAP1GAP2,EPB41L3,KLHL7,COBL,TAC1,TACC1,CAMTA1,FBXW11,TBL1X,TBX15,ARHGEF12,TPM1,RICTOR,ZIC2,TMEM198,PMEPA1,ST7,JMJD1C,GAN" MicroRNA hsa-miR-574-5p:Functional MTI Functional MTI miRTarbase 2.89E-50 1.62E-46 9.23E-50 8.50E-49 113 415 "PTCHD1,NLGN4X,CARNS1,MARCH4,PCDH10,BCAS1,ARRB1,MARCH3,THSD7A,RUNX1T1,GPR37L1,FOXN3,RAB3C,KIAA1549L,NRXN1,TMEM184B,IGLON5,NCAN,PPP1R16B,ST18,PYGO1,LONRF1,DBT,DNAJC6,JAKMIP2,TMEM130,SV2B,CHRDL1,DMD,CDON,GNE,ABI2,EN2,EPHA5,KATNAL1,TBC1D16,FGF14,UBE2E3,EFCAB2,C15orf41,FAXC,MMADHC,GFRA1,GLI2,GLYR1,PCDH11X,DIPK1C,IL1RAPL1,BVES,SYNPO,ZDHHC15,IGF1,NKD1,KCNB1,KLHL23,KCNQ3,SMAD9,MAP2,MITF,HS6ST3,MYO5A,NEXMIF,NOS1,OLR1,OXTR,KCNK10,GPR173,NLGN3,ZNF655,PLEC,SDK2,SPATA6,PRKCB,MAPK10,PROX1,SH3TC2,RGS4,TTLL7,PGBD4,KIAA0895L,KCNIP3,SATB1,CSRNP3,SLITRK3,RPH3A,SON,SOX5,ZHX3,NMNAT2,KIF1B,NCDN,ARHGEF9,MGRN1,ATMIN,ZEB1,TRIM2,TMEM151B,HHIP,THRA,DDHD1,NR2E1,TNR,DOK6,LRTM2,VSNL1,PORCN,KCNK12,ELFN1,DPYSL5,STOX2,KAT6A,ZDHHC20,SSPN" MicroRNA hsa-miR-4728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.84E-50 2.16E-46 1.23E-49 1.13E-48 163 838 "XKR4,ADAR,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,ASPH,TTLL9,ADGRB2,SYNJ2,FOXK1,HAP1,CAMK2A,ISPD,CBS,SLC16A4,MYOM2,ARHGEF2,LONRF2,CDR1,DLGAP3,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,PHYHIP,TOMM20,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,ABI2,RASA4,PLEKHA1,MRNIP,ANKRD13B,IGSF6,WAC,TRMO,PNMA2,KBTBD12,TRAF3IP2,HBS1L,NKX6-2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,PADI2,SCRG1,AGBL5,ZNF491,SOWAHA,IGF1,DOCK7,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,CCDC80,MSI1,JAKMIP3,SAMD14,NBL1,NDUFA5,NEUROD2,NFIX,NOVA2,SLC11A2,NRGN,TBC1D25,OGDH,OGG1,ZNF713,PDGFRA,GPR173,BEST3,PFKFB3,CDK14,CCSER2,RETREG2,FAT3,PPP2R2B,PTPA,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,RAB5B,CEP97,PLEKHB2,SH3TC2,IQSEC3,PRRT2,MORC4,MYH14,PGBD4,EMID1,HES6,MYO18A,CLSTN1,SLC1A2,PEX26,SMTN,PKNOX2,ZKSCAN3,ZCCHC24,IQSEC2,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,HHIP,ARL10,THRA,ERCC6L2,KCTD2,TMPRSS5,SSBP2,RFTN2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,NAV2,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-378:mirSVR_highEffct hsa-miR-378:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.98E-50 2.24E-46 1.27E-49 1.17E-48 158 792 "SORCS1,SLC44A5,ARHGAP20,FAM135A,OGT,DDO,TMEM263,PLA2G4C,CAPRIN2,EIF4G3,NOL4,BCL2L2,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,CDC27,CDH8,LGI1,TIGD7,COPB2,SYNPR,PPT2,KIAA1549L,CLCN4,DNAJB5,C4orf33,RAB26,AHCTF1,ZFP28,CDC42BPB,CREM,ARHGEF10,PHF14,CTNND1,USP6NL,CCDC144A,RIPOR2,DCAF8,FRMPD4,DCC,DDX46,GRIN3A,HS3ST4,DOCK2,DSCAM,DYRK1A,EBF1,WDPCP,HIPK3,RBM12,SH3GLB1,CELSR3,KMT5B,ENPP6,SPEG,FABP7,FCGR1A,CEP78,FCGR3A,FGF12,TMEM164,ATP5PD,FOXG1,FLT1,C2orf88,CAMKK2,ATP2C1,ST6GALNAC3,MPP6,GABRB1,GABRG2,ERAP1,GLS,GNAS,GPT2,TDRKH,GRIA4,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,MAN1B1,HMGB1,SMAP1,MYLK2,IL6ST,IL11RA,KIF2A,KIF5C,MARK1,CD200,CTNNA3,LYRM9,NAP1L3,NCAM1,NDP,NEK1,NEUROD1,NF1,NFE2L2,CHAMP1,LOC100128398,PAK3,CAMKV,C11orf49,TRHDE,PRKACB,PRPSAP2,DCHS2,SIDT1,SNRK,PTPRD,USP47,RGS4,ELP2,FBXW7,BAALC,KCNIP2,KCNIP1,RXRG,RAB3GAP1,ATF7IP,SORCS3,MBD5,IQSEC2,EPB41L3,NEK4,DIP2A,ACSBG1,PLCB1,CAMTA1,AGTPBP1,DMXL2,FRYL,ZFPM2,AP4E1,GZF1,SEZ6L,PPIL6,BEST1,GUSBP1,TRIM9,PLPP4,SLC26A10,EML6,ZNF189,CADM2,PRTFDC1,EPM2A,ST7,CAMK1G,ZNF248" MicroRNA hsa-miR-155-5p:TargetScan hsa-miR-155-5p TargetScan 4.10E-50 2.30E-46 1.31E-49 1.21E-48 109 387 "HECW2,FAM135A,KIF6,C6orf89,LCORL,APC,ARRB2,ASTN1,DOCK11,BACH1,KSR1,FUBP1,FOXK1,CACNA2D1,CACNB4,CBFA2T2,REPS2,NMT2,NGEF,QKI,LETMD1,CSF1R,PITPNM3,SEC14L5,KIAA0087,G3BP2,CD99L2,DYNC1I1,DMTF1,EBF1,PHC2,KCTD3,ELAVL2,ELAVL4,C3orf18,EN2,ETV1,SCML2,MEX3B,FOXO3,FLT1,ANKFY1,FUT9,NRG3,GABRA1,CAB39,RAB30,GNAS,GPM6B,RAPGEF4,PARD3B,KIF3A,MIER3,AGFG1,PLD5,IL6R,IL6ST,METTL21A,KCNA1,PAXBP1,LRP1B,MEIS1,MMP16,RSPO2,NFIA,NFIX,NFYA,NOVA1,PDE3A,PIK3R1,FTO,LRP12,KANSL1,CEP41,PKIA,PKN2,PROX1,PTPRD,ARID4A,BSDC1,RDX,RFX3,SEC61A2,CYB561D1,SALL1,SATB1,IL17RB,CHD9,FBXO11,ANKRD6,BTBD3,CPEB4,MBD5,PALLD,KDM3A,HECW1,NFASC,FAM168A,SATB2,AHCYL2,HHIP,C5orf64,DOK6,RICTOR,SCG2,NAV3,PDSS2,HNRNPA3,FXR1" MicroRNA hsa-miR-3191:mirSVR_lowEffct hsa-miR-3191:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.30E-50 2.98E-46 1.69E-49 1.56E-48 129 542 "DPF1,SYN3,GPRIN1,AP2A2,AK2,UNC79,PKP4,API5,SFMBT2,PDXK,ARNTL,PDE8B,CHID1,KSR1,DST,CACNA1D,CACNG1,CALB1,BRSK2,ARHGEF1,ZMYM4,EVI5L,TPP1,QKI,FHL5,IQCK,TBPL1,CLIP3,CS,FEZ1,GPSM1,RUBCN,ARHGAP32,DAPK1,DLG2,DNM2,DPH1,ARRDC4,GPR61,PHF20L1,RASA4,CDHR1,FCGR1B,ZNF589,IP6K2,AGAP2,FOXM1,EVL,FLT1,ERGIC3,FYN,PRLHR,GRB10,C1QL4,ADAMTS13,GRIN2D,SLC2A6,ATXN2L,MSL1,ZNF678,KCNJ9,KCNMA1,KCNN1,PAXBP1,MEIS1,MOBP,MSI1,FXYD7,FXYD6,NEUROD2,NFIX,NINJ2,NRGN,OGDH,ZDHHC22,PALM,PDPK1,PFKFB3,KCTD15,SLC25A23,PILRA,KANSL1,PRKCZ,SIDT1,UHRF1BP1,ELOVL2,PTPRE,PTPRG,SLC25A48,RAP1GAP,ZDHHC14,DUSP15,PRIMA1,RNF220,ARMC5,RPE,MCMBP,SGSM1,RYR3,AMER2,SCN3A,BCAN,LIMS2,SLC6A7,SEPHS1,SNRPN,SPTB,TSPYL2,NPAS3,C11orf87,MESP1,SSPO,TTBK2,TMEM150C,KAZN,WWC1,SIN3B,TCF7L2,RPGRIP1L,PHF24,SLC19A3,CYB561A3,LRRC8A,TNS1,AMACR,VGF,RICTOR,PHTF2,VANGL2" MicroRNA hsa-miR-1468:mirSVR_lowEffct hsa-miR-1468:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.10E-50 3.43E-46 1.94E-49 1.79E-48 131 559 "FMNL2,AK2,PPFIA2,EPB41L5,MAGEE2,ARNTL,RGS20,MARCH3,DACT3,ADGRB3,BCL2L2,CACNA1A,USP6,SCARB1,C1orf52,CDH2,LGI1,TIGD7,CHN2,KMT2C,DLGAP3,PPT2,FBXO7,C4orf33,CNTN1,IQCK,COL11A2,GDA,FEZ2,MICAL2,CNTNAP2,RASGEF1C,TM9SF4,KIAA0319,SV2B,RABGAP1L,FAM107B,GPR61,EML1,EMX2,CLVS1,TOMM40L,TESK2,GORAB,MED12L,AFF2,KHDRBS3,PHYHIPL,ZMAT1,ERAP1,GCNT2,NUDT21,NR3C1,GRM7,BTN2A1,COQ10A,BVES,LINGO1,RNFT2,AGBL5,SMAP1,EID2B,KIAA1755,KCNA1,KCNK1,KIF2A,HECTD2,CTNNA3,NEXMIF,SETD4,P2RX7,NLGN3,PMP22,MBOAT7,TMEM235,MINDY2,PPP2R5C,KANSL1,RAB39A,MASP1,DEF8,PIGG,PTPRG,FAM120C,CEP97,ZNF793,KHDRBS2,ZDHHC14,BSDC1,GAL3ST4,ZYG11B,TTLL7,LGI2,ROBO2,PRR5L,ZNF354C,SBF1,LINC00461,PPP1R9A,NTNG1,FBXO11,SLC11A1,TMCC1,SCN3B,DOP1A,KDM3A,TEX2,KIF1B,CLASP2,ZC4H2,SS18,SULF2,KAZN,TRIM2,RALYL,HIF3A,SLC44A1,ENHO,TIAM1,TMPO,RUSC1,TSC1,LINC00689,VLDLR,CA10,GAL3ST3,NAV3,GOPC,MRPL47,UBE3B,MSRB3" MicroRNA hsa-miR-18a*:mirSVR_highEffct hsa-miR-18a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.25E-50 3.51E-46 1.99E-49 1.83E-48 145 678 "SYN3,ACTN2,NDRG2,ADD2,BRAP,SLC12A5,FAM135A,DPP10,DGKZ,SEMA4G,ARNTL,MARK4,ATM,B3GALT2,BACH1,DCAF5,NRP2,WASF1,CACNA2D1,LDB2,INA,AIFM1,CHGB,SRP14-AS1,NIPBL,WHRN,SLC35F1,CPS1,HAPLN1,TRIM69,SNCAIP,ARHGEF10,MICAL2,CSNK1E,NCAN,GREB1,ARHGAP32,IP6K1,COPS7A,SLC12A6,PHC2,PHF20L1,SUGP2,KMT5B,ABI2,RCSD1,HSPA12B,ACSL4,FER,C2orf88,SORBS1,ATP2C1,B3GAT1,ALDH1L1,BRD8,PRRC2B,GRIA4,RFFL,LINC00839,RNF165,ZBTB49,AP4S1,RABL2A,SLC2A6,PADI2,KLF12,SMAP1,JAK1,CDH20,KCNC1,KCNK2,STXBP5,NCOA7,POC1B,AFF1,MYO9A,ZC3H12B,NF1,CNOT4,NOVA1,NTRK2,PDGFRA,GDAP1L1,CAMKV,PLCB2,PURG,PRRX1,PPP1R1A,PPP3CB,PKIA,HYDIN,MASP1,CNTLN,BDNF-AS,STK32A,PID1,CEP97,RDX,SLC6A15,ARHGEF10L,CCDC82,RAVER2,MRAP2,FBXW7,FAM192A,HOGA1,SOX6,ITSN1,NTNG1,PPP4R3A,SLC6A11,SLC12A2,RCOR3,IFT122,MAPKBP1,UNC80,SON,ENKUR,NECAB1,FGD4,NUDT10,SYP,ASTN2,ANO4,USP32P1,GPR161,TMPO,RIMBP2,PIK3R5,LILRA4,ELP5,FNDC5,DCBLD1,KCNE5,HEPACAM,CADM1,FLRT2,CFAP298,UPF3A,PRDM8,CAB39L,PCBP4,WNK2,RNF170,MSRB3" MicroRNA hsa-miR-224:PITA hsa-miR-224:PITA_TOP PITA 6.44E-50 3.62E-46 2.05E-49 1.89E-48 103 346 "ACLY,RBM10,ADAR,TMEM132B,SLC12A5,GPR158,ANK3,APBA2,USP37,RASL11B,DDX3Y,SLC4A4,BTRC,CAST,C1orf52,REPS2,CDC42,CCPG1,FOXN3,CHN1,QKI,MAP4K4,PCYT1B,IGDCC3,USP6NL,FBXL5,WDR20,DNM1,USP3,CPEB2,DPYSL2,MAMLD1,EDNRA,HIPK3,FRY,EFNA3,EFNB3,MBNL2,KATNAL1,ACSL4,FGF14,AMOTL2,SUCO,FAM49B,NPTN,BRPF3,GK,TCERG1,SPIN1,TNRC6A,GPM6A,CIT,HMGCR,AGFG1,KCNK2,KCNMA1,STMN1,MBNL1,MID1,HS6ST3,MYO5A,NF1,CNTN3,PFKFB3,PIK3C2A,HMGCLL1,PRRX1,SH3KBP1,POU3F2,MED1,RELN,WBP1L,FAM120C,PTX3,OXR1,RADX,ZFHX4,CARF,CASC3,TRA2B,ITSN1,CHD9,RUFY2,MYT1L,SOX11,KDM3A,ZNF423,POGZ,NKAIN2,SEPT3,ARHGEF9,ARHGEF12,PUM2,FRYL,TPM3,FNDC5,FAM155A,SMARCAD1,SLC17A6,RTN4,KAT6A,ZDHHC20,SLC4A10" MicroRNA hsa-miR-1259:PITA hsa-miR-1259:PITA_TOP PITA 6.62E-50 3.72E-46 2.10E-49 1.94E-48 98 312 "SNX30,LRRC7,ALCAM,FAM135A,ARHGAP5,NIPA1,CACNB4,PTBP2,DGKI,SEPT7,FOXN3,CNR1,SLC4A7,PREPL,LRIG1,ATRNL1,DOCK4,FRMPD4,MYEF2,DLG3,DNM1,YAF2,MBNL2,RCAN2,NRN1,AFF2,NBEA,PHYHIPL,NCKAP1,GATM,PCDH17,GHR,PCDH11X,GPR22,FAM19A2,BVES,MAP4K5,HMGB1,SMAP1,C5orf24,KCND2,HECTD2,ARHGAP12,MAP2,MEF2C,RSPO2,NEUROD1,PCDH9,PRTG,PDPK1,GNG2,PIK3R1,PRRX1,IRX1,MED1,MAPK4,PROX1,QRICH1,PTPRB,PTX3,RDX,ZFHX4,SCP2,CASC3,SH3BGR,FNDC3A,SLC1A2,WDR47,SLC6A1,SEPHS1,CPEB4,FAM126B,PDZRN3,KDM3A,LARP4,ERBIN,NECAB1,CAMTA1,EHBP1,SATB2,RALYL,DICER1,ZFPM2,AKTIP,KAT6B,SGK3,AMOT,KCNT2,CADM2,LRP8,PRDM8,TUBA1A,FZD3,HNRNPA3,KLHDC1,SOCS4,SLC4A10,SENP7" MicroRNA hsa-miR-802:TargetScan hsa-miR-802 TargetScan 7.30E-50 4.10E-46 2.32E-49 2.14E-48 94 286 "ABAT,ARID1A,HECW2,KCTD16,APBB2,APC,ATP1B3,MTMR9,DST,CACNA1I,MAP7,C1orf52,DCLK1,FOXN3,CLCN3,KIAA1549L,CLCN4,NMT2,QKI,ARMC8,RTTN,PNPLA8,LIN54,MATR3,JAKMIP2,G3BP2,DOCK2,DPYSL2,DSCAM,RCAN1,DNM1L,EDIL3,MBNL2,ABI2,PAN3,DCTN4,EPHA5,MEX3B,FAM49B,NEURL4,MEGF11,CAB39,RAPGEF6,GLUL,GPR37,GUCY1A2,MIER3,NEGR1,AGFG1,LRRTM3,KCNB1,KLHL23,IPO5,MBNL1,MEF2C,MSI1,MYO9A,PCSK5,PDE4D,CDK14,PLCL1,PPP3CA,BCAS3,PTCH1,PTPRG,GTDC1,PBRM1,MCMBP,ATXN1,CASC3,CPEB3,BTBD7,CPEB4,MBD5,FAIM2,NMNAT2,ERC1,CDK19,EXOC7,NSD1,ARHGEF12,AHCYL2,ITGB3BP,HHIP,DDHD1,RBFOX2,CA10,CSDE1,EVI5,SCG2,GOPC,HNRNPA3,JMJD1C,NETO2" MicroRNA hsa-miR-766:mirSVR_highEffct hsa-miR-766:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.77E-50 4.93E-46 2.79E-49 2.57E-48 153 751 "ACADM,ASIC1,METAP1D,AP2A2,TAOK1,AMPD2,SUGT1P4-STRA6LP-CCDC180,APBB1,NT5C3B,PPFIA3,RGS20,DNAH17,RIPK1,MTMR2,RAB29,CALB2,AIFM1,CDH2,CHGA,RAB33A,DNAJB5,AKAP6,BTF3L4,CSF3R,VAC14-AS1,PLXNA4,FAM169A,GREB1,DCAF4,CYBB,GPRASP1,HP1BP3,DNM1,HS3ST2,DTNA,TOM1,FARSB,PHC2,EFNA3,PHF20L1,PAN3,SEZ6,TLR7,F8,ATP13A4,NOP56,DCTN2,NSG2,NRG3,GABRB1,RAPGEF6,ZNF274,ZNF559,DISC1,TUBA8,SESN1,RND1,GLDC,TNRC6A,GNAS,PSRC1,GPD2,RAPGEF4,GRIA2,PLCD4,BTN2A1,RNFT2,MAP4K5,ATXN2L,HNF4G,IGF1,ZNF678,INSM1,CDH20,KCNJ3,KCNK2,STMN1,C2orf80,ZFYVE27,MBD1,TM6SF1,DDX25,LAYN,RTL5,PCBP3,NUCB2,SNTG1,DUSP26,NLGN3,PLXNB3,POU3F2,MINDY2,PPP1R1A,PRKCG,WBP1L,TMEM104,PSMD13,PTHLH,QDPR,SLC25A48,ZNF493,RET,ZDHHC4,RGS4,ARHGEF10L,SEC61A2,EXD2,NEK11,EPHA10,GLDN,TCP11L1,SALL1,LRFN5,LINC00461,SEC14L1,SH3GL3,SLC1A3,SLC9A5,MYH15,KIF13A,FAM219A,PDZD2,KDM4C,SPTB,LARP4,NKAIN2,INKA2,APOM,CEP68,SEPT3,FGD4,SYNE2,ARHGEF9,FBXW11,VWA3A,GPRIN3,MTMR14,TPM1,TPM3,TMPRSS5,HSPBP1,SLC35A4,BCL2L13,BEST1,SLC47A2,ZNF28,MKRN3,WNK1,CADM2,GDPD5,HPS4,PPP1R3F,CASC15" MicroRNA hsa-miR-508-5p:mirSVR_highEffct hsa-miR-508-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.14E-50 5.14E-46 2.90E-49 2.67E-48 145 680 "KCNH8,SLC25A25,CSMD3,KLHL32,CCDC85A,CC2D2A,FGD2,SUGT1P4-STRA6LP-CCDC180,APBB1,ALS2,TNRC6C,MIER1,RGS20,ATP2A2,ATP2B1,SYNJ1,CAST,LDB2,AIFM1,RAB33A,CNRIP1,SLC35F1,FAM171B,AKAP12,PDE4DIP,GREB1,CYBB,ZFYVE16,DCC,ZEB2,C2CD2L,TMCC2,WDR20,DMD,DTNB,FCF1,KLHL5,EFNA3,EGR3,F8,CLVS1,CEP78,GORAB,KIAA1109,ATP13A4,ANKFY1,HVCN1,CELF1,GABRB1,GAD2,IQGAP2,TUBA8,ARFIP1,FREM1,RAB30,GLS,TNRC6A,GRIA2,GRIA4,PLCD4,GRM5,MFSD2A,MAP4K5,HPS5,HNF4G,SHISA6,NKD1,SCIN,INSM1,C2CD4C,LAMP2,ARHGAP12,COL28A1,BLOC1S2,NEFH,NF1,PCSK1,PDE4B,BEST3,ABCB1,PLP1,PLXNB3,PSAT1,SLC36A4,GRAMD1C,PTK2,TMEM260,RBBP6,RGS7,RIC8B,RPRD1A,EXD2,CARF,ARMH4,FBXW7,BAALC,ACER3,LRFN5,ELMOD1,FUZ,FBXO11,SLA,KANSL3,NAPB,KIF13A,SNRPN,UNC80,UHRF1BP1L,SEPT3,FAM168A,FGD4,ANKRD28,ATP11A,TBL1X,KLHL4,SATB2,GPRIN3,FRYL,FAM200B,DICER1,CRB1,ARL10,MTMR14,BHLHB9,ERCC6L2,TMOD1,TPD52,TPM1,TRIO,TRO,TSN,HSPBP1,AMOT,PLEKHH2,CCDC14,CFAP298,TRIM9,ZNF45,LMAN2L,HPS4,TMEM163,C12orf4,CASC15,TIGD6,SLC4A10" MicroRNA hsa-miR-1250:mirSVR_lowEffct hsa-miR-1250:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.09E-49 6.11E-46 3.45E-49 3.18E-48 127 529 "ACLY,CSMD3,KLHL32,FZD9,AP2A2,RTL9,CC2D2A,PLA2G6,UPRT,ALS2,APOC2,ATP1A1,MYOM1,ADGRB3,NRP2,CFLAR,LDHD,KSR1,ARHGEF7,NAE1,CASTOR3,BSN,CA8,KALRN,TRIM41,AIFM1,DGKI,CDH8,CNR1,BTF3L4,SH2B1,RGS6,MICAL2,NCAN,SOCS5,VAC14-AS1,PHF14,CFAP61,RIMS2,CCDC144A,MYADM,ARMCX4,ZNF804A,ZEB2,FAM107B,DNM2,ATN1,DTNA,DTNB,DNAJB6,PHF20L1,EGFR,COPS4,LRRC17,FDFT1,KAT8,OLFM1,FGF11,SPSB4,FGF13,NELFCD,POMT1,NRG3,GCNT2,GPR37,BTN2A1,MFSD2A,AGBL5,HSF2,IGSF1,SCIN,SCRT2,SFXN5,MAT2A,MKLN1,CTNNA3,MYO7A,NOVA1,LOC100128398,ETFRF1,PCDH8,FTO,FA2H,RELN,WBP1L,SIDT1,PXK,PTPRO,SLC25A48,RGS12,PKNOX2,LRRC55,SMARCE1,ANKRD36,LIMCH1,RIMS1,PALLD,BDP1,BEX1,LRRC4,MPRIP,KLHL7,FNDC9,ANKRD28,CAMTA1,MLST8,EXOC7,ADGRL3,TBCEL,IQCE,RPGRIP1L,RALYL,ITGB3BP,TNFRSF1B,PRRT1,KAT6B,TPM1,TPM2,ZFP37,CELF4,SPIRE1,UPF3A,RNF103,TMEM178A,FIP1L1,PHTF2,JPH3" MicroRNA hsa-miR-502-3p:mirSVR_highEffct hsa-miR-502-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-49 6.20E-46 3.50E-49 3.23E-48 126 521 "ACTN1,NDRG2,KIAA1324,ARHGAP20,OGT,APAF1,GPAM,USP37,ASPH,DDX3Y,BCL7A,DST,JAZF1,CACNB2,PTBP2,SLC25A14,INA,CDC27,ZMYM4,CNN3,RCHY1,HAPLN1,RNF14,CFAP61,ECE2,DCAF8,ZNF337,DAPK1,SIRPA,ZEB2,HP1BP3,RHOBTB1,CCDC3,NR1D2,CPEB2,DRD1,DNAJB6,KCTD3,ELAVL2,F3,FCGR1A,UBE2E3,AGAP3,ATP13A4,JKAMP,NBEA,TACC2,ATP6V1H,STAU2,GABRB3,AHCYL1,ARPP21,DISC1,MSTN,GLI2,PCDH11X,TDRKH,MCHR1,GRIA2,CIT,BVES,RBPJ,KCNN2,CYP27C1,MBD1,TM6SF1,AFDN,JAKMIP3,MYCN,NEFM,NF1,OGDH,CLDN11,PCDH9,PCSK5,PDE3B,GDAP1L1,PMP22,CCDC144B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,PRKCZ,MAPK9,BDNF-AS,PTHLH,ACSM5,SH3TC2,DBX2,SLC6A15,ZFHX4,RPL15,UEVLD,ATP8B4,SATB1,SCN2A,NTNG1,SLITRK3,ST3GAL3,SEPHS1,EPC1,RCOR3,TRERF1,HECW1,KDM4C,PEG10,ZBTB43,NPAS3,SEPT8,PRRC2C,ATP11A,DDHD2,ITGB3BP,HEY1,DDHD1,CADM1,UBE2H,KCNT2,EML6,ZNF189,CSDE1,PCDH15,AMN1,GAN,LAS1L" MicroRNA hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 1.12E-49 6.32E-46 3.56E-49 3.28E-48 101 334 "CPNE2,KCNH8,FMNL2,ADD2,GRAMD1B,PITPNM2,ANXA7,CDK13,NCOA1,NUMB,ATP1A2,NOL4,MTMR3,CACNA1E,CAMK2G,REPS2,CFL2,FADS2,ARMC8,AKAP6,COL9A1,CLOCK,AKAP12,ANKRD44,PHF19,DNAL1,DNAJC6,DLG2,CPEB2,EFNA2,GPR61,ABI2,EGR3,PLXNC1,ENPP6,CEP85L,APC2,EYA1,PHYHIPL,GABRB1,ILDR2,NEK6,ATP8A2,PCDH17,PPARGC1A,OS9,GPR26,CECR2,RAPGEF1,GRIK3,RNF165,RASSF8,MIER3,HES5,KCNA4,LSAMP,MAPT,MBNL1,MITF,NCAM2,NEUROD2,NFIA,NHLH1,OCRL,PCMT1,PDE4D,PDGFRA,PIK3C2A,FTO,PPP2R2C,PPP2R5C,BCAS3,PIGG,FIGN,KLHL11,ROBO1,RORB,FBXW7,RXRA,SATB1,CSRNP3,ATXN1,CPEB3,NTNG1,BTBD7,CXXC4,RIMS1,FAM126B,ARHGAP26,NPAS3,LMO3,GSE1,MMS19,CLASP1,ARHGEF12,DOK6,NR2C2,HEPACAM,CLIP2,NDRG4,CADM2" MicroRNA hsa-miR-1244:PITA hsa-miR-1244:PITA_TOP PITA 1.22E-49 6.84E-46 3.86E-49 3.55E-48 90 262 "KCNH8,GALNT13,ADD3,SORCS1,BCAR3,CNIH2,TMEFF1,CADM3,NOL4,BCL7A,BTRC,CALB1,CALM1,REPS2,DCLK1,QKI,FGFR1OP2,TOX,MAML1,G3BP2,MTX3,WDR20,DYNC1I1,RBM12,SH3GLB1,TENM1,PAN3,GPHN,ERBB4,EYA1,MED12L,FOXM1,HVCN1,KHDRBS3,PHYHIPL,GABRB3,EML4,GPR37,TPPP,GRIA4,MAEL,ZHX1,KLF12,AGFG1,KCNMA1,MBNL1,MEIS2,LAYN,NFIA,NOVA1,SERPINE2,HMGCLL1,PPP2R5E,RAB39A,MAPK4,MAPK8,SNRK,PTN,ZSCAN32,PTPRD,PTPRN,RAD52,EXD2,SCN2A,FAM19A1,PPP1R9A,CPEB3,NTNG1,FBXO11,SLC20A2,SMARCC2,KDM3A,ZNF423,CLASP2,ITPRID2,NXT2,FAM168A,PLCB1,ANKRD28,FBXW11,DDHD1,SSBP2,UBE3A,VLDLR,WNK1,EVI5,PARP6,FXR1,DPF3,SOCS4" MicroRNA hsa-miR-509-5p:PITA hsa-miR-509-5p:PITA_TOP PITA 1.22E-49 6.85E-46 3.86E-49 3.56E-48 95 294 "CSMD2,TAOK1,ZNF687,AMPD2,ANK1,MAP4K3,ALS2,CDC14B,ARHGAP5,NUMB,CAMK2G,CANX,RUNX1T1,ZNF501,DCLK1,SRSF11,DNAJB5,QKI,AKAP6,COL4A5,ZNF521,NCAN,CTNND1,MAML1,MAGI2,G3BP2,DPYSL2,YAF2,TENM1,EPB41,OLFM1,GALC,MSTN,GHR,TNRC6A,MSL3,CIT,IL1RAPL1,ZHX1,BACH2,MIER3,AGFG1,KCNA1,KCND2,KCNMA1,KIF5C,MBNL1,MEIS1,MN1,MDGA1,NCAM1,ZC3H12B,NOS1,GPR137C,GPR85,CCSER2,RETREG1,LRRN3,KANSL1,BCAS3,TMEM260,PTPRZ1,RIPOR1,USP47,FIGN,ZFHX4,SETD5,RYR3,ATXN1,SCN2A,SCN3A,SCAF8,SH3GL2,NLGN1,TET1,RCOR3,RIMS1,FAM126B,WDTC1,SOX11,ZNF423,TAB2,LRRC4,CAMTA1,FBXW11,EHBP1,TRIM2,RPGRIP1L,AZIN2,ZFAND5,SLC30A4,SNX27,WNK3,PDSS2,HNRNPA3" MicroRNA hsa-miR-509-3-5p:PITA hsa-miR-509-3-5p:PITA_TOP PITA 1.22E-49 6.85E-46 3.86E-49 3.56E-48 95 294 "CSMD2,TAOK1,ZNF687,AMPD2,ANK1,MAP4K3,ALS2,CDC14B,ARHGAP5,NUMB,CAMK2G,CANX,RUNX1T1,ZNF501,DCLK1,SRSF11,DNAJB5,QKI,AKAP6,COL4A5,ZNF521,NCAN,CTNND1,MAML1,MAGI2,G3BP2,DPYSL2,YAF2,TENM1,EPB41,OLFM1,GALC,MSTN,GHR,TNRC6A,MSL3,CIT,IL1RAPL1,ZHX1,BACH2,MIER3,AGFG1,KCNA1,KCND2,KCNMA1,KIF5C,MBNL1,MEIS1,MN1,MDGA1,NCAM1,ZC3H12B,NOS1,GPR137C,GPR85,CCSER2,RETREG1,LRRN3,KANSL1,BCAS3,TMEM260,PTPRZ1,RIPOR1,USP47,FIGN,ZFHX4,SETD5,RYR3,ATXN1,SCN2A,SCN3A,SCAF8,SH3GL2,NLGN1,TET1,RCOR3,RIMS1,FAM126B,WDTC1,SOX11,ZNF423,TAB2,LRRC4,CAMTA1,FBXW11,EHBP1,TRIM2,RPGRIP1L,AZIN2,ZFAND5,SLC30A4,SNX27,WNK3,PDSS2,HNRNPA3" MicroRNA hsa-miR-3132:mirSVR_highEffct hsa-miR-3132:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.39E-49 7.79E-46 4.38E-49 4.04E-48 146 691 "RALGAPA1,ADAR,DSCAML1,ADD2,PLEKHH1,DPY19L2P4,MTUS1,AGT,KCTD16,TXNDC16,CARNS1,AMPH,APC,VAT1L,SEMA4G,CAPRIN2,DCAF5,NFS1,CD86,C1orf52,CDH10,CCPG1,CHGB,CHM,CNOT8,DNAJB5,SULT4A1,FAM149A,ZFP28,CPS1,SEC24C,ATRNL1,ERC2,NRSN1,RIMS2,AK5,KIF19,DLG3,DMTF1,DTNA,DYRK1A,DNM1L,HIPK3,FRY,TMEM132E,AASS,EPHA5,RABEPK,MRPL37,TLR7,GMPR2,CACNG3,PPP1R1B,ZNF589,FGR,UBE2E3,SMC2,AP4B1,GAD2,IP6K3,DISC1,TUBGCP4,SRCAP,GLS,LOXL3,GNAS,GPD2,EML4,GRID1,MFSD2A,HMGB1,AGBL5,IDH3B,IL6ST,KCNK1,LIMS1,SYTL4,VWA5A,GPR155,MARK1,LDLRAD3,KCTD6,NFIA,PAX6,DPY19L2P2,PDE1A,NALCN,SEMA5B,SPATA6,FA2H,KANSL1,GRAMD1C,GDPD2,SPDL1,PTPRN,HKR1,ERI2,MORC4,RFX4,RFX5,RPRD1A,SETD5,PNMA8A,ROBO1,SPIN3,TCP11L1,RPS6KA2,LRRK2,KCNIP2,CSRNP3,FAM19A1,SCN8A,CHD9,BCAN,ARHGEF40,TET1,SMARCC2,BDP1,TEX2,ZC3H13,EPB41L3,GANAB,VAMP1,SYT5,KAZN,TBCEL,SIN3B,DMXL2,SATB2,WDR7,FRYL,GALNT17,ICAM5,ERCC6L2,TMPO,TNR,METTL3,SGK3,FAM155A,GORASP1,NDRG4,MEIS3,CA10,EMSY,PRDM10,CAMK1G" MicroRNA hsa-miR-873-5p.2:TargetScan hsa-miR-873-5p.2 TargetScan 2.07E-49 1.16E-45 6.54E-49 6.03E-48 105 364 "CPNE2,CSMD2,ADCY6,KIAA1211,RNF150,ALAD,OGT,ANK3,MARK4,CCDC74A,ASPH,CADM3,BCL7A,FGF17,NIPA1,LURAP1,DIRAS1,BRSK2,DGKI,REPS2,JAM2,NRXN3,LETMD1,RIMS4,PITPNM3,NOS1AP,MYADM,PHF19,MATR3,RIMS3,PHYHIP,IST1,DGKG,SCRN1,MYEF2,KLHL3,DLG3,DYRK1A,CELSR3,EPB41L1,RTN3,EZH1,KIAA1109,FGF1,FHL1,FOXM1,ANKFY1,FAM49B,CELF1,C15orf41,CPLX1,PCDH17,RAPGEF1,KAT7,NCKAP1L,DDX19B,HLF,HNRNPK,NKD1,KCNA1,KCNB1,LIFR,MBD1,CHIC1,MEF2C,MOG,CCDC80,MDGA1,MXI1,NFIX,NOVA1,DDR2,OPHN1,GPR137C,PBX1,PCSK5,FTO,KANSL1,CEP41,DIRAS2,NDUFS7,GON4L,PTAFR,RAD51D,RORB,ATXN1,ELMOD1,HSPA4L,PPP1R9A,MYO18A,FBXO11,HECW1,PEG10,NPAS3,LRRC4,DDHD2,FBXW11,PSD3,GPRIN3,AHCYL2,CADM1,MFF,PARP6,GDPD5,NHSL1" MicroRNA hsa-miR-486-5p:mirSVR_highEffct hsa-miR-486-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.28E-49 1.84E-45 1.04E-48 9.53E-48 116 447 "KCNH8,NCKAP5,KLHL32,BEND6,AK2,FAM135A,MRTFA,SUGT1P4-STRA6LP-CCDC180,MAGEE2,ARHGAP5,DYNLL1,NRP2,CA8,CCNH,CDH18,SRSF11,NRXN3,NIPBL,CNGA3,ARMC8,SLC4A8,DCC,ZEB2,LYPD1,DTNB,DYRK1A,RASGRP1,RBM12,AASS,EIF1,GPHN,FGF13,PRELID3A,CELF1,GPR153,CSPG5,GABRB3,INPP5K,GCNT2,DBF4,FERMT2,PSRC1,RFFL,CIT,TMEM25,NXPH2,FRMD3,MIER3,MYLK2,LRRC25,KCNK2,PIK3AP1,MARK1,MATN2,MEIS1,MXI1,NEUROD1,ALDH1L2,HCN1,PAK3,PIK3R1,ZNF655,PLXNB3,TRHDE,MAPKAP1,POLG,PPM1B,CRLS1,PPP3CB,RAD51D,RBBP6,RFX4,RGS4,NUDT11,NEK11,BAALC,ST6GALNAC6,ZNF331,NLGN1,SLC1A3,BTBD3,MYH15,RCOR3,MBD5,PDZRN3,PDZD2,SOX2,IDI2-AS1,SMOC1,ST5,KANK1,PRRC2C,DNAJC9,SYPL1,WSCD1,PUM2,TEK,SIRT1,SLC44A1,ERCC6L2,R3HDM1,C5orf64,CADM1,UGT8,SLAIN1,PLEKHH2,MTCH1,CCDC14,REEP1,ZSCAN26,SMARCAD1,SLC38A1,SCG2,MRPL47,FXR1,SLC4A10" MicroRNA hsa-miR-190a-5p:TargetScan hsa-miR-190a-5p TargetScan 3.48E-49 1.96E-45 1.10E-48 1.01E-47 73 167 "HECW2,OSBPL6,ANXA7,PARG,LDLRAD4,CACNB2,CACNB4,HAP1,RUNX1T1,CDH2,DCLK1,NRXN3,CLCN3,CNR1,CLOCK,MYEF2,MFAP3L,CEP170,MAGI2,BLOC1S6,DMD,ELAVL4,RCAN2,GPHN,FGF14,MEX3B,NBEA,NRG3,MPP6,GABRB1,C15orf41,CPLX2,PCDH17,GPR26,GUCY1A2,HAS2,BACH2,NEGR1,AGFG1,IGF1,KCNA4,KCNB1,KIF2A,LRP1B,MEF2C,MYO5A,MYO9A,NEUROD1,NFIA,NOVA2,HCN1,P2RY1,PAX6,SDK2,POU3F2,DIRAS2,PTCH1,PTHLH,MARCH1,ROBO2,RIMKLA,HSPA4L,ITSN1,FNDC3A,NLGN1,CXXC4,MBD5,NFASC,DICER1,CSMD1,CA10,NAV3,GAN" MicroRNA hsa-miR-190b:TargetScan hsa-miR-190b TargetScan 3.48E-49 1.96E-45 1.10E-48 1.01E-47 73 167 "HECW2,OSBPL6,ANXA7,PARG,LDLRAD4,CACNB2,CACNB4,HAP1,RUNX1T1,CDH2,DCLK1,NRXN3,CLCN3,CNR1,CLOCK,MYEF2,MFAP3L,CEP170,MAGI2,BLOC1S6,DMD,ELAVL4,RCAN2,GPHN,FGF14,MEX3B,NBEA,NRG3,MPP6,GABRB1,C15orf41,CPLX2,PCDH17,GPR26,GUCY1A2,HAS2,BACH2,NEGR1,AGFG1,IGF1,KCNA4,KCNB1,KIF2A,LRP1B,MEF2C,MYO5A,MYO9A,NEUROD1,NFIA,NOVA2,HCN1,P2RY1,PAX6,SDK2,POU3F2,DIRAS2,PTCH1,PTHLH,MARCH1,ROBO2,RIMKLA,HSPA4L,ITSN1,FNDC3A,NLGN1,CXXC4,MBD5,NFASC,DICER1,CSMD1,CA10,NAV3,GAN" MicroRNA hsa-let-7e:mirSVR_highEffct hsa-let-7e:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.66E-49 2.05E-45 1.15E-48 1.06E-47 158 805 "ARID1A,KLHL32,ERMN,ADRB2,KIAA1324,AMT,MAP4K3,SUGT1P4-STRA6LP-CCDC180,ARHGDIA,ARRB2,DACT3,SLC4A4,ATP2B1,ZNF583,BACH1,GYG2,CACNB2,TRIM41,AIFM1,NDST3,C7orf61,PPT2,COG1,QKI,MAP4K4,NIPBL,SLC25A27,AHCTF1,IGDCC3,MFSD4A,ZNF385A,OSBPL3,FRMPD4,DAPK1,B3GAT3,DLG2,DMD,DPP6,SLC25A18,ABCC5,GOLT1B,E2F5,E2F6,EDN1,SYT15,RASGRP1,FAM13A,APH1A,AASS,EIF4G2,PLEKHO1,LRRC17,RACK1,FCGRT,GORAB,FGF11,FGR,SUCO,SYNCRIP,RGPD5,C2orf88,DOT1L,ZNF512,GABBR1,GABRA2,GALNT15,FAM120B,GALC,C15orf41,GATM,CYP46A1,POLL,CNTRL,ADAMTS8,PRDM5,BTN2A1,RABL2A,RASSF8,DDX19B,VSIG4,AGBL5,SOWAHA,LRRC25,NKD1,IGSF1,NME9,KCNC2,KCNJ11,KCNK1,MDM4,MEIS2,MOBP,RSPO2,NAP1L1,FXYD6,CNOT4,NOVA1,OGG1,GPR85,SERPINE2,XRN1,PRRX1,POLR2F,PKIA,GDPD1,MASP1,PTK2,TMEM255A,RDX,DPF2,ERI2,FIGN,RFX5,RGS3,RGS12,RIC8B,SETD5,C12orf49,ROBO1,ATP8B4,LGR4,MEG3,ST6GALNAC6,CLIP1,MIR124-2HG,FAM19A1,FNIP1,KIF27,FNDC3A,PAAF1,KIF1B,CLASP2,NXT2,ELOVL4,DIP2A,ADHFE1,GANAB,ANKRD28,ACSL6,TCF12,CRB1,TGFBR3,CDH22,MTMR14,FAM124A,TPM2,PDSS1,RICTOR,LYPD6,SMARCAD1,SYNC,PRDM2,STOX2,C12orf4,UBE3B,PHTF2,ZNF248,GAN" MicroRNA hsa-miR-1303:PITA hsa-miR-1303:PITA_TOP PITA 4.05E-49 2.28E-45 1.28E-48 1.18E-47 89 259 "SORCS1,API5,SHTN1,DACT3,BSN,CH25H,LRBA,MAGI1,CHN1,TBPL1,SLC32A1,CNTNAP2,ERC2,PUM1,SCRN1,ELMSAN1,ELMO1,APH1A,EGR3,FGF1,FGF11,FOXO3,TACC2,STAG2,GAD2,DNER,GATM,TCERG1,ZHX1,MIER3,ZNF546,KCNA1,INSYN2,MAG,MATN3,MBD1,NDP,NOVA1,OPCML,PCDH9,ENPP2,PLP1,TRHDE,POU3F2,PPP2R5E,PPP3CA,PTCH1,PTPRD,FAM120C,CEP97,KHDRBS2,RDX,ZYG11B,RIC8B,ZFHX4,SALL1,CSRNP3,ATXN1,LRRTM4,SCN8A,PPM1E,WDR37,FAM81A,ZHX3,ARHGAP26,SRPK2,ITPRID2,LARP4,ZC3H4,PRRC2C,ANKRD28,CAMSAP2,FAM208A,VWC2,TCF4,TCF12,AHCYL2,AKTIP,TJP1,R3HDM1,RBFOX2,AMACR,FAM155A,TOM1L2,ZIC1,SMARCAD1,CADM2,CERS6,SENP7" MicroRNA hsa-miR-4297:mirSVR_highEffct hsa-miR-4297:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.10E-49 2.31E-45 1.29E-48 1.19E-47 134 593 "CPNE2,ZNF608,HECW2,OSBPL8,AK2,PPFIA1,SUGT1P4-STRA6LP-CCDC180,APP,AQP4,AQP6,ARNTL,BARD1,ZNF599,KSR1,DST,CASTOR3,CALB2,THSD7A,CALM1,CAMK2G,TRIM41,INA,CHN2,SUMF2,SLC4A8,SLITRK5,DZIP3,UBXN2A,CTNND2,DOCK4,KIAA0586,ARMCX4,DNAJC6,GSDME,SMG7,RABGAP1L,EXOG,RAB39B,HS3ST4,CPEB2,GNE,EDIL3,CNNM1,SEMA3D,SRRM1,MRPL37,NRN1,SCML2,FER,FGFR1,GABBR1,SYT17,DISC1,RAB30,RAB40B,GRIA2,GRIA4,PLCD4,GRIN1,RNF165,UBE2QL1,PACSIN2,ZNF491,SHISA6,EID2B,MYLK2,RBPJ,KCNC2,KCNJ3,STMN1,SYTL4,SHC3,MEIS1,NRBP2,CTNNA3,MYL3,NDP,CCDC13,DNHD1,GPR137C,PIK3CD,FAM216A,PLCB2,PMP2,POU3F2,SIDT1,PTN,PTPRE,RDX,MORC4,SEC61A2,EXD2,KIAA0895L,ATP8B4,SGSM1,ZNF331,FAM19A1,SEPHS1,SMARCE1,PDZRN3,LMO3,MPRIP,TACC1,ADGRL3,CUX2,SYNE1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,TEK,ARL10,KAT6B,TPM3,C9orf85,RGMB,RFTN2,CADM1,RPL7L1,ZNF709,SF1,ZIC1,ZIC3,TCEAL7,ANKS1B,SPIRE1,SMARCAD1,DNALI1,KCNAB1,DOCK8,TIGD6" MicroRNA hsa-miR-1537:mirSVR_lowEffct hsa-miR-1537:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.42E-49 3.61E-45 2.02E-48 1.86E-47 127 537 "METAP1D,PSMG3-AS1,PNMA8B,PITPNM2,LRRC4C,MIER1,MARK4,ATP2B2,SLC2A11,MTMR9,ADGRB3,BARD1,ARHGEF7,CALB1,RUNX1T1,CLDN10,LDB2,CDC27,LARGE1,CACNA2D2,CHM,NRXN3,FAM19A5,ARMC8,FAM149A,MYRIP,C2CD2,ST18,KIAA0408,KIAA0319,TMCC2,SEC16A,DPH1,ABCC9,EDNRA,CNNM1,SUGP2,VPS13B,ETV1,EZH1,TAOK3,STRADA,FDFT1,KIAA1109,SLC37A3,CAMKK2,STAU2,NCKAP1,ERAP1,DISC1,SRCAP,AHDC1,LUZP2,FERMT2,ATF7,STMN2,BVES,SOX21,GUCY1B1,IGSF21,HMGB1,HSF2,INPP5B,LRRTM3,KTN1,LSS,LYPLAL1,AQP11,MBP,MIA2,MITF,MMP16,MOBP,NAP1L1,NTRK2,OCRL,OXTR,PCDH8,PKD1,PMP22,TRHDE,MAPKAP1,LRP12,ING3,EPB41L4B,FA2H,POU3F2,PPP2R5C,VSTM2L,PTPRE,OXR1,CCDC25,ELP2,RPL15,RPS20,ELMOD1,FHOD3,SLC22A4,SON,SOX2,ZCCHC24,NMNAT2,CAND2,ZNF423,KIF1B,NPAS3,LARP4,NECAB1,ASTN2,WWC1,WDR7,RALYL,DICER1,SIRT1,TIAM1,HEY2,RASD2,TSC1,TUB,RPRM,CLIP2,ZIC2,PRDM2,CSDE1,RNF103,FAM47E,UBE3B" MicroRNA hsa-miR-183-5p.1:TargetScan hsa-miR-183-5p.1 TargetScan 6.54E-49 3.67E-45 2.06E-48 1.89E-47 105 368 "RNF157,OSBPL8,PKP4,GPAM,LRRC4C,NRP2,CDK5R1,CACNA1E,CAMK2D,RUNX1T1,REPS2,NRXN3,CLCN3,QKI,AKAP12,CSNK1G3,PLXNA4,FAM169A,PLCXD3,DOCK4,LIN54,KLHL3,RHOBTB1,SACS,RABGAP1L,CALN1,CPEB2,DTNA,CELSR3,ABI2,GOLGA7,RGS17,MRVI1,MED12L,PCYOX1,ARFGAP2,ATP2C1,CELF1,CAB39,NCKAP1,RAB30,KDM2B,MAP7D2,PRUNE2,EML4,RAPGEF4,NR3C1,PRDM5,BVES,MAP4K5,FRMD5,BACH2,HLF,HTR2A,ICA1,C5orf24,CLVS2,KLHL23,KCNK2,KIF2A,HECTD2,LSAMP,MBNL1,MDM4,LRP1B,MEF2C,HCN1,P2RY1,KCNK10,PDE3A,PDE4D,KCTD15,MED1,PPP2R5C,PRKACB,MAPK4,PTCH1,CEP97,KHDRBS2,RFX3,ROBO2,SCN2A,SCN3A,SCP2,PPM1E,NTNG1,PKNOX2,KIF13A,ARHGAP26,NPAS3,LMO3,DIP2A,KANK1,AJAP1,GSE1,FAM168A,PSD3,RIMBP2,KCTD2,CSMD1,EVI5,CERS6,FRMD6,RNF146,GAN" MicroRNA hsa-miR-425*:mirSVR_lowEffct hsa-miR-425*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.93E-49 3.89E-45 2.18E-48 2.01E-47 122 497 "NCKAP5,GPRIN1,TMEM132B,RNF150,LCNL1,KCTD16,FGD2,PHF12,SUGT1P4-STRA6LP-CCDC180,APC,PPFIA3,PCDHGB4,STX16,BACH1,CACNA1G,CAMK2D,TRIM41,ARHGEF2,ZBED1,CDH2,KCNAB3,LARGE1,RAB33A,MAP4K4,SLC4A8,FEZ1,NOS1AP,TCAF1,DCAF8,ZNF337,MATR3,IST1,DNAJC6,ZEB2,KLHL3,DLG2,OLIG1,DMTF1,ACOT8,TOM1,FAM135B,CACNG7,EIF1,EMX2,KCNMB2,MRPL37,CDKL3,RTN3,ADGRV1,TBC1D16,IP6K2,CAMKK2,GPD2,STON1,GRIA2,ADAMTS13,CLASRP,MFSD2A,MSL1,C5orf24,ITGAM,ITPKA,KCNA1,KTN1,MT3,SCG3,FXYD7,NELL1,ALDH1L2,NFIX,NOS1,NRGN,PALM,PCDHGC3,ZFYVE21,PLXNB3,PURG,PSAT1,VSTM2L,PRKAB2,BCAS3,WDR25,CNTLN,OXR1,SEMA6D,ATXN7,SH3BGR,MAGI3,SLC6A8,SLC12A4,SLC20A2,SPHKAP,SNCA,UNC80,SATB2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,AZIN2,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SYNPO2,TSC1,HEPACAM,MGAT5B,NSD2,SLC30A4,CSDE1,NAV2,FIP1L1,LINC00632,ST7,NLRP3,TTC7A" MicroRNA hsa-miR-324-3p:mirSVR_highEffct hsa-miR-324-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.99E-49 4.49E-45 2.51E-48 2.31E-47 127 538 "GALNT16,SLC12A5,CDC42BPA,PI16,CNIH2,APBB1,CACHD1,PPP4R4,ARRB1,STK33,DNAH17,DPY19L3,SYNJ2,ARHGEF7,CACNA1D,TRIM41,LRBA,LRRFIP1,PPT2,NIPBL,SLC25A27,COX4I1,CRMP1,ABCG1,SEC24C,GREB1,ZSCAN23,ECE2,DCAF8,YTHDC1,C8orf34,ZEB2,MAGI2,DDX46,SV2A,RABGAP1L,DPP6,DSCAM,WDPCP,EDN3,FCF1,KLHL5,FRY,PHF20L1,ELAVL4,BSCL2,SEZ6,EPHB1,DUSP27,SCML2,TOMM40L,ZSCAN30,FDFT1,IP6K2,EFCAB2,WDR83,TRIM16,CGREF1,OGA,STAG2,GABBR1,NEU3,DCLK2,PLCD4,ADAMTS8,AP4S1,RNFT2,WIF1,LINC01102,FAM95B1,SOWAHA,KIF5A,KIF5C,MTR,MXI1,LYRM9,NKX2-2,SETD4,OPHN1,ZNF827,CAMKV,PIK3R1,HMGCLL1,PNMA3,PPP5C,CNTLN,MTMR10,STK32A,ZCWPW1,RGS4,RPRD1A,ZNF532,TMLHE,NEK11,SCN8A,COPZ1,ITSN1,NTNG1,HKDC1,CNKSR2,FAM214B,SLC9A5,SORCS3,HECW1,TEX2,DBNDD2,TSPYL2,TAB2,SS18,GANAB,FGD4,SEMA4A,TBCEL,THRA,TPM3,ELP5,TRPC1,ZMYND8,CADM1,ZBTB14,ZNF711,INTS3,PRDM2,DNALI1,PARP6,WNK2,HNRNPA3" MicroRNA hsa-miR-539-3p:TargetScan hsa-miR-539-3p TargetScan 8.59E-49 4.82E-45 2.70E-48 2.48E-47 98 320 "ARID1A,KLHL32,CCDC85A,GRAMD1B,HACE1,ARHGAP20,ANK3,APBB2,GAS7,CASK,FOXK1,CACNA1B,RUNX1T1,AIFM1,REPS2,FOXN3,KMT2C,NRXN1,ABCG2,CLIP3,ERC2,PLCXD3,HDAC4,CEP170,MAGI2,NTM,CHRDL1,HS3ST4,NR1D2,PDCD6IP,DYRK1A,DNM1L,FAM13A,ELAVL2,CALCRL,EPB41L1,ETV1,DLC1,FGF12,CAMSAP1,FLT1,GABRA4,CPLX2,PPARGC1A,GRID1,GRIK3,NR3C1,KAT7,BVES,BACH2,HPSE2,IL6ST,LSAMP,MEIS1,MEIS2,HS6ST3,MXI1,NFIA,HCN1,PCSK5,PDE4D,FAM98B,FTO,NXPH1,PKIA,PROX1,PTPRD,PEX5,RAD51D,ERI2,FIGN,RNF220,HUNK,KIF21A,CPEB3,PREX2,EPN2,MAPKBP1,PDZD2,KIF21B,RBM26,CLSTN2,FAM168A,C3orf70,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DDHD1,ANKS1B,EVI5,HNRNPA3,CPNE4" MicroRNA hsa-miR-485-3p:TargetScan hsa-miR-485-3p TargetScan 8.59E-49 4.82E-45 2.70E-48 2.48E-47 98 320 "ARID1A,KLHL32,CCDC85A,GRAMD1B,HACE1,ARHGAP20,ANK3,APBB2,GAS7,CASK,FOXK1,CACNA1B,RUNX1T1,AIFM1,REPS2,FOXN3,KMT2C,NRXN1,ABCG2,CLIP3,ERC2,PLCXD3,HDAC4,CEP170,MAGI2,NTM,CHRDL1,HS3ST4,NR1D2,PDCD6IP,DYRK1A,DNM1L,FAM13A,ELAVL2,CALCRL,EPB41L1,ETV1,DLC1,FGF12,CAMSAP1,FLT1,GABRA4,CPLX2,PPARGC1A,GRID1,GRIK3,NR3C1,KAT7,BVES,BACH2,HPSE2,IL6ST,LSAMP,MEIS1,MEIS2,HS6ST3,MXI1,NFIA,HCN1,PCSK5,PDE4D,FAM98B,FTO,NXPH1,PKIA,PROX1,PTPRD,PEX5,RAD51D,ERI2,FIGN,RNF220,HUNK,KIF21A,CPEB3,PREX2,EPN2,MAPKBP1,PDZD2,KIF21B,RBM26,CLSTN2,FAM168A,C3orf70,PCDHAC2,PUM2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DDHD1,ANKS1B,EVI5,HNRNPA3,CPNE4" MicroRNA hsa-miR-1254:mirSVR_highEffct hsa-miR-1254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.08E-48 6.05E-45 3.38E-48 3.11E-47 147 711 "CLK4,EMILIN3,SORCS1,GRAMD1B,MTUS1,C1QTNF3,PHF12,PPFIA1,CNTNAP1,ZFYVE28,ARHGAP5,MARCH3,CAPRIN2,SLC4A4,ZNF582,SLC2A11,KSR1,KALRN,CAMK2D,MAP7,USP6,LARGE1,CASC2,CNOT8,PPT2,DNAJB5,C4orf33,SRP14-AS1,NIPBL,LETMD1,AHCTF1,MFSD4A,CLIP3,CS,RGS6,SEC24C,FAM169A,RASSF2,ZEB2,SV2B,SRGAP3,RPS6KL1,DOCK2,DMTF1,DSCAM,SUGP2,KMT5B,ABI2,TMEM132E,SORBS3,EPHA5,EPHB1,ERBB2,TUBB3,POLR1B,FGF11,FGF13,FGFR1,TMEM107,SMC2,B3GAT1,MSANTD4,MPP6,FYN,GABRA2,SRCAP,PPARGC1A,RUNDC3A,TOX3,ADGRA3,GPD2,RAPGEF1,GRIN2C,LINC01551,AGBL5,CPT1C,HTR5A,IRF8,NKD1,USP54,NME9,CYP27C1,AQP11,PPM1L,GIT1,MYO5A,PABPC1L2A,NF1,NOVA1,DNHD1,NRCAM,ZNF713,PDE3A,BEST3,PFKFB2,SNX10,PCDH18,MAPKAP1,ING3,SEPT4,FAT3,PPP3CB,PIGG,PTAFR,RAD52,NWD1,ZNF493,RASGRF2,ARID4A,FEZF2,KIF7,UEVLD,PRR5L,TCP11L1,KCNIP2,CLIP1,HES6,SOX6,KIF27,ZFP30,ST3GAL3,SMARCD3,SNRPN,UNC80,SON,HECW1,RBM26,ERBIN,ADHFE1,ANO4,CUX2,SYNE1,FRYL,CHST8,MTMR14,FNDC5,TSC1,ANO5,FLRT1,PLEKHH2,MEAF6,BEST1,VSNL1,SF1,FSTL5,CADM2,PIANP" MicroRNA hsa-miR-891b:PITA hsa-miR-891b:PITA_TOP PITA 1.08E-48 6.07E-45 3.39E-48 3.12E-47 90 268 "SLC12A5,PCDH19,OSBPL1A,API5,ATP2B3,SYNJ1,LDLRAD4,BTRC,LDB2,CDC42,NRXN3,BTF3L4,SLC4A7,FAM171B,OSBPL3,RIMS2,TOX,LONRF1,KLHL3,DLG2,DYNC1I1,RBM12,SH3GLB1,EGR3,ETV1,SUCO,FOXO3,PDLIM5,DKK3,TNRC6A,TMEM121B,FAM19A2,MIER3,HMGB1,KCNJ3,KCNJ10,MAP2,NEXMIF,NELL1,NEK1,NFYA,NTRK2,ENPP2,GPR85,PIK3R1,PPP3CB,GRAMD1C,PRPSAP2,SYTL2,SNRK,PTPRD,GTDC1,FBXW7,SOX8,SALL1,ATXN1,SCP2,CHD9,NLGN1,ABLIM3,RUFY2,SLC8A2,CCDC88A,SLC12A2,MYT1L,SOX11,NMNAT2,KIF1B,SS18,ELOVL4,SYT11,SYN2,SYPL1,COBL,CAMSAP2,TCF4,SATB2,TCF12,AKTIP,RIMBP2,KCTD2,KAT6B,SSBP2,TUBB1,FLRT2,ZFAND5,WNK3,CERS6,FXR1,FRMD6" MicroRNA hsa-miR-744:mirSVR_lowEffct hsa-miR-744:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.08E-48 6.09E-45 3.40E-48 3.13E-47 149 729 "ASIC2,ASIC1,CLK4,FAM43B,PLEKHH1,UNC5A,ZNF608,CC2D2A,PITPNM2,AMPD2,SEMA7A,SUGT1P4-STRA6LP-CCDC180,APOC1,PPFIA3,SPTBN4,ARHGDIA,ARRB2,NUMB,CADM3,SYNJ2,CASTOR3,CACNA1E,DDR1,TRIM41,USP2,ARHGEF1,KCNAB3,ASIC3,TAOK2,TMEM59L,FADS2,IQCK,ARMC8,ZNF385A,C2CD2,C1QL2,AATK,MICAL2,CALY,IP6K1,PITPNC1,SGSM2,FAM107B,NYAP1,DNM2,DPH1,DNM1L,TMEM132E,C3orf18,CEND1,EZH1,ZIC4,TUBB4A,FCGR1A,TOMM40L,GTF2IRD2,AMOTL2,SEMA6C,NOP56,FLYWCH1,GPR153,SALL3,INPP5K,ALDH1L1,GFRA2,LYVE1,GPER1,GRIA1,GRIN2D,GRM7,AP4S1,HPSE2,OPALIN,LRRC75A,KCND1,KCNK2,LINC00634,KLC1,MAN2A2,ADAM11,LDLRAD3,FXYD6,RCOR2,NPTX2,NRGN,TBC1D25,OGDH,ZNF827,ZDHHC8,CAMKV,FAM216A,FXYD1,PLXNB3,PILRA,NKAIN4,PPP5C,PRKAB2,MASP1,BCAS3,TMEM260,PYGM,CCDC40,IQSEC3,BSDC1,PRRT2,ARHGEF10L,ARMC5,NEK11,GLDN,SYNDIG1,ATAT1,DRAXIN,ATXN2,TRIM46,MAGI3,BCAN,FAM81A,SLC6A8,NAXD,MAST1,SNCB,WDTC1,SOX3,SOX10,SP2,C11orf87,CAMTA2,ZFR2,SYN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,FBXL16,RELL2,PRRT1,ELP5,DCBLD1,RUSC1,CLEC2L,TOM1L2,KLC2,NT5M,DNALI1,URM1,WNK3" MicroRNA hsa-miR-3117:mirSVR_highEffct hsa-miR-3117:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-48 6.16E-45 3.44E-48 3.16E-47 138 632 "KCNH8,ADD1,ADRB2,SPOP,FAM135A,PPFIA1,APP,SHTN1,TMEFF1,SNAI3-AS1,NRP2,DST,RUNX1T1,ASIC3,CHM,SYNPR,LHX2,CLCN3,ARMC8,SUMF2,COL9A1,SLC4A8,ABI3BP,MFSD4A,HS3ST5,RNF14,ATRNL1,VCAN,SLITRK5,PHF14,GREB1,NRSN1,GPRASP1,EARS2,MAML1,ARMCX4,HP1BP3,EXOG,DYNC1I1,DPH1,PDCD6IP,RGS17,EPHA5,DENND4A,CLVS1,CACNG3,FDFT1,GORAB,FGF12,ANKFY1,SORBS1,AP4B1,GAB1,ZMYND11,IP6K3,DISC1,SULT1C4,PCDH11X,STARD3,ZNF638,LUZP2,GPT2,LNX1,GRID1,GSTT2,IRAK3,MAEL,NXPH2,NEGR1,TCEAL6,HTR5A,LIMS1,VWA5A,HECTD2,NCOA7,ZNF680,BCO1,NAP1L3,NCAM2,NF1,PDE1C,PDGFRA,BEST3,PSAT1,PIGG,TMEM260,QDPR,RAP1GDS1,RASGRF1,ARID4A,SLC6A15,RFX5,CARF,ABCA11P,SEMA6D,SATB1,CSRNP3,LRRTM4,ZFP2,KIF21A,DOCK10,NTNG1,SHC4,ATF7IP,CPEB4,RCOR3,BDP1,KDM4C,COLGALT2,NKAIN2,PLCB1,MMS19,DDHD2,ATMIN,TCF4,CLASP1,SLC44A1,TIAM1,DDHD1,ZFP91,ERCC6L2,TMPO,PDSS1,AMACR,TRPC1,ZMYND8,HEPACAM,OSBP2,BCL2L13,ZNF74,ZNF189,DHX33,PPP1R3F,SLC17A6,PAK5,HNRNPA3,NHSL1,SENP7" MicroRNA hsa-miR-490-3p:mirSVR_highEffct hsa-miR-490-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.10E-48 6.17E-45 3.44E-48 3.17E-47 122 499 "SDE2,ACTN2,DPY19L2P4,OGT,MAP4K3,UPRT,SHTN1,TMEM263,STK33,ZNF583,C5,IL33,CALB2,KALRN,MAP7,CLDN10,KYAT1,CERS5,LRBA,ARHGAP33,MAGI1,KMT2C,CLCN4,TPP1,LY86,NIPBL,CNR1,AHCTF1,ANKRD44,CCDC144A,ZFYVE16,HEPH,FBXL5,SMG7,AK5,RABGAP1L,FSD1L,RBM12,KMT5B,ELAVL2,RGS17,VPS13B,MFSD10,CEP85L,ZNF589,POLR1B,PNMA2,NRG3,DKK3,GABRB1,GABRG2,ZMYND11,NEK6,IGSF5,MSTN,ADAM28,PCDH17,GLS,STMN2,GRIA1,GRIA2,GRM1,UBE2QL1,HTR5A,RBPJ,IL6R,IL11RA,TTYH2,NCOA7,CLEC18A,ZNF680,MSI1,MYO7A,NEK1,CNOT4,CHAMP1,SNTG1,PDE4D,PDGFRA,NALCN,A2ML1,MBOAT7,RAB39A,GRAMD1C,HYDIN,MDGA2,ZSCAN32,OXR1,GTDC1,KIF7,BAALC,ADAL,KCNIP2,ZFP2,ITSN1,SH3GL3,DOCK10,MAGI3,PEX26,PKNOX2,SLC6A7,SHANK2,SMARCE1,ANKRD36,FAM126B,SOX5,SP4,CAND2,ZSCAN29,DIP2A,NUDT10,DNAJC9,SYT1,TMEM136,SLC44A1,TP53BP1,TPD52,ZKSCAN5,UGT8,PRDM2,VPS35L,ADAMTSL3" MicroRNA hsa-miR-33b:PITA hsa-miR-33b:PITA_TOP PITA 1.10E-48 6.18E-45 3.44E-48 3.17E-47 84 231 "SLC25A25,FMNL2,SLC12A5,GPR158,UNC79,CDC42BPA,DPP10,ANK3,B3GALT2,CAMK2G,USP6,LGI1,FOXN3,CHN2,KIAA1549L,MAP4K4,GDA,SEC24C,ST18,ZFYVE16,ZEB2,WDR20,DLG4,RCAN1,CNNM1,EN2,ATP8A1,OLFM1,AFF2,SALL3,MSTN,GHR,PPARGC1A,SPIN1,HTATSF1,GPD2,BACH2,KCNA4,KCNMA1,MARK1,MEF2C,MEIS2,NAP1L2,NFIX,NPY,NOVA1,GPR88,PDGFRA,ENPP2,XRN1,PCDH18,PACSIN1,PPP3CA,PPP3CB,DIRAS2,SLC6A15,FBXW7,SCN8A,CASC3,GALNT10,CPEB3,SLITRK3,WDR47,SOX11,ENKUR,ERC1,SYT11,VPS13A,TCF4,SATB2,WASHC4,RIMBP2,CSMD1,TNS1,TPM3,TRPS1,KCNE5,TBC1D15,DPYSL5,NAV3,WIPF2,SLC17A6,GOPC,SLC4A10" MicroRNA hsa-miR-455-3p:PITA hsa-miR-455-3p:PITA_TOP PITA 1.35E-48 7.57E-45 4.22E-48 3.88E-47 88 256 "KCNH8,FMNL2,NLGN4X,AP2A1,OSBPL8,SEMA6A,PPFIA3,TMEFF1,ATP1B3,NOL4,MAGI1,CACNA2D2,SOCS6,LHX2,KMT2C,NRXN1,CLTC,SLC35F1,PNKD,TENM4,SLITRK5,CHRDL1,DLG4,CDON,DRP2,FRY,RBM12,TMEM35A,ETV1,RTN3,FGFR3,BAIAP2,MEX3B,ARFGAP2,B3GAT1,DKK3,GABRG2,GLDC,FERMT2,GPD2,HAS2,GABARAPL2,SCRT2,KCNA1,KCND1,KCNJ4,PACRG,MYO6,NFIX,NOVA1,PCDH9,PIK3R1,RETREG1,PPP2R5E,PRKAB2,RELN,USP47,PBRM1,SALL1,SLC1A2,SLC1A3,SMTN,SLC8A1,SLC12A2,CDK19,RBM26,SS18,SYN2,ACSL6,TCF4,DMXL2,ARHGEF12,PUM2,FRYL,SIRT1,SLC44A1,HEY1,PRMT8,FNDC5,VSNL1,XPO1,MICU3,EMSY,PARP6,SNX27,SLC17A6,C12orf4,CPNE4" MicroRNA hsa-miR-22:mirSVR_highEffct hsa-miR-22:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.43E-48 8.01E-45 4.46E-48 4.11E-47 139 642 "FMNL2,RNF157,PLEKHH1,GRAMD1B,DPY19L2P4,OSBPL6,FAM135A,AMPH,ARRB1,RGS20,CDK13,ATM,CCDC181,TTLL9,BACH1,SGCE,WASF1,VXN,CERS5,AIFM1,ZMYM4,CHGA,SLIT2,NIPBL,TMEM155,IGLON5,MFSD4A,CSF1R,VCAN,PLCXD3,ARMCX4,MYEF2,C2CD2L,MAGI2,FBXO25,SNAP91,PDCD6IP,EDNRA,PHF20L1,ABI2,VPS13B,EPB41L2,EPHA5,EPHB1,ERCC2,MRPL10,ETV1,RTN3,DNAJC27,RPS6KC1,TOMM40L,SEC23B,TACC2,UFM1,FAM49B,NPTN,ZNF605,STAG2,IP6K3,SYT17,DNER,MYOZ2,GATM,SESN1,KIRREL3,ZNF638,PCLO,GRM5,GUCY1B1,MAEL,ARHGAP36,AGBL5,HNF4G,SMAP1,MSL1,C5orf24,INPP5B,OLFM3,MAT2A,MEIS2,PPM1L,POC1B,CCDC80,NDUFA5,NEFM,NELL2,NF1,NOVA1,PDE1A,DUSP26,GDAP1L1,GPSM2,PLCL1,MAPKAP1,WDR25,PLPPR1,RAB5B,TMEM255A,ERI2,RIC8B,ELP2,NEK11,FBXW7,SPIN3,ACER3,ITSN1,NTNG1,CHD9,ANKRD6,RUFY2,SEPHS1,RAB3GAP1,KDM3A,ZC3H13,KIF1B,NPAS3,NXT2,ADHFE1,PRRC2C,NUDT10,CAMSAP2,SATB2,SYNE1,SIRT1,ITGB3BP,MTMR14,KAT6B,PDSS1,ZKSCAN5,CADM1,CLDND1,GPR158-AS1,ZBTB38,MAP3K12,KCNAB1,CAMK1G,NLRP3,ZNF248,LAS1L" MicroRNA hsa-miR-1204:mirSVR_lowEffct hsa-miR-1204:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.48E-48 8.34E-45 4.64E-48 4.27E-47 131 574 "ASIC2,GPRIN1,UNC5A,AP1B1,CC2D2A,CDC42BPA,DPP10,ANK2,FGD2,APBA2,UPRT,PHYHD1,PPFIA3,CDK10,ASCL1,ATP2B3,TTLL9,ARHGEF7,SLC16A4,CDC27,MAGI1,KMT2C,NMT2,FADS2,LY86,SLC4A8,MYRIP,ENTPD4,PLCH2,HDAC4,INTS1,DBI,ARMCX4,RUSC2,DDX46,RHOBTB1,USP3,SLC29A4,DPP6,ATN1,GNE,EDN3,SUGP2,EPB41,DMTN,CD320,TMEM132C,TUBB3,KAT8,WDR83,SALL3,GATM,ALDH1L1,CRCP,STARD3,KCNMB4,GNAS,DIDO1,ADAMTS13,PACSIN2,HMGCL,ICA1,KNDC1,KCNC1,CAMK2N2,SFXN5,MAP2,MAP6,IL17D,MYT1,HNRNPM,VWA2,TBC1D25,CDK18,PDPK1,DUSP26,GDAP1L1,NALCN,SEMA5B,PLIN1,NECAB2,FSD1,PCDHB17P,LRRN3,SIDT1,GON4L,PIGG,ZNF615,RAD51D,ARID4A,DPF2,GTDC1,ZDHHC4,RORB,NEK11,HSD11B1L,KCNIP3,ITSN1,MAGI3,DHX30,SEPHS1,SLC14A1,NAPB,MAPKBP1,TNIK,TSPYL2,DDN,LRRC4,ST5,STAU1,SEPT3,KLHL7,SYNE2,SYP,ALG1,WSCD1,TPCN2,WDR7,DOCK9,SLC19A3,FRYL,AHCYL2,PMS2CL,SYNPO2,BCL2L13,CCDC136,CCDC14,ZNF70,NDRG4,HPS4,SIGLEC10" MicroRNA hsa-miR-218-1*:mirSVR_highEffct hsa-miR-218-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.55E-48 8.69E-45 4.83E-48 4.45E-47 147 713 "NCKAP5,SYS1,SLC12A5,CEP126,ABCD2,SUGT1P4-STRA6LP-CCDC180,TTLL9,BID,CACNB2,KALRN,PTBP2,CAPN3,SPAG9,ARHGEF2,SEPT7,CDC27,CDH8,LRRFIP1,PLAA,ARMC8,ZFP28,CP,NCOR2,SIPA1L1,PDE4DIP,SLITRK5,APPL1,ZSCAN23,HDAC9,TOX,PHF19,IP6K1,JAKMIP2,MFAP3L,EDIL3,KMT5B,EPHA5,ZNF549,MRPL37,PTK2B,CEP78,FER,FGF1,FGF12,FGFR1,SGIP1,POMT1,GABBR1,BRPF3,TCERG1,TNRC6A,DCLK2,GNAS,WDFY3-AS2,ADGRA3,GRM7,TMEM25,LINC01551,AP4S1,RNFT2,NXPH2,ELOVL5,HTR2A,DOCK7,ZNF678,LRRTM3,NME9,KCND2,KCNN3,KHK,MAP2,KCTD6,THYN1,HCN1,IGSF11,OCRL,CHAMP1,PCSK5,PIRT,GNG2,BEST3,PFKFB3,OLA1,PLCL1,ANKRD16,MINDY2,PPP3CB,PKIA,MAPK9,MAPK10,CNTLN,ZSCAN2,RASGRF2,ZYG11B,RFX2,RIC8B,CCDC82,UEVLD,RTKN,TMEM156,SAFB,SEMA6D,SCN2A,FNIP1,PEAR1,SH3GL3,FERMT1,NLGN1,ZNF365,SHANK2,SLC12A2,SMARCE1,IFT122,UNC80,DOP1A,MYCBP2,IDI2-AS1,ZC3H13,SPART,SRPK2,CLASP2,ADHFE1,KANK1,AJAP1,SYNE2,C12orf76,TACR1,ADGRL3,EHBP1,WDR7,PCDHB9,SLC19A3,ARHGEF12,PUM2,TJP1,ERCC6L2,CDK20,VLDLR,ZIC3,MKRN3,ZNF138,EML6,LRP8,LINC02210,HPS4,ITM2C,CASC15" MicroRNA hsa-miR-1207-3p:PITA hsa-miR-1207-3p:PITA_TOP PITA 1.90E-48 1.07E-44 5.93E-48 5.47E-47 91 276 "FZD9,PCDH19,TAOK1,CNTNAP1,MARK4,DDX3Y,ATP2B3,NOL4,BSN,MAP7,RUNX1T1,FMNL3,ZMYM4,DLGAP2,CACNA2D2,CFL2,NRXN2,CREB5,CHD5,PPP1R16B,ST18,GPRASP1,DCAF8,RIMS3,IST1,CTIF,RUSC2,COPS7A,DLG3,RBM12,EFNB3,MBNL2,ENO2,EPB41L1,DMTN,ANKRD13B,ERBB4,SPEG,BAIAP2,NBEA,MEGF11,BRPF3,SRRM4,SRCAP,TTBK1,TMEM121B,GRIA4,CIT,SCRT2,CLVS2,L1CAM,INSYN2,MAPT,MSI1,MDGA1,MYO6,MYO9A,NEXMIF,NBL1,NFIX,NOVA1,ZNF827,PBX1,PIK3R1,FAT3,RASGEF1B,TMEM255A,ARID4A,BSDC1,SETD5,CYB561D1,SCN2A,SCN3A,PRCD,TNFRSF19,SGK1,NTNG1,NKAIN2,STX1A,SULF2,GANAB,ANKRD28,UNC5D,CUX2,SZT2,TNS2,HEY1,RELL2,TPM3,RGMA,URM1" MicroRNA hsa-miR-760:TargetScan hsa-miR-760 TargetScan 2.16E-48 1.21E-44 6.74E-48 6.21E-47 112 424 "ABAT,EMILIN3,ADARB2,ADCYAP1R1,ADD2,GRAMD1B,MTUS1,KIAA1324,GOLGA7B,C6orf89,ALS2,FAM131A,ARNTL,ATP2B2,BCL2L2,CDK5R1,MTMR2,CACNA1I,CAMK2G,FMNL3,DGKI,REPS2,CDH8,CDR1,GPR37L1,KIAA1549L,COL9A2,MAGED1,NRG2,IGDCC3,NCOR1,SEC24C,CNTNAP2,PUM1,KIAA0513,DGKG,ELMSAN1,FAM107B,DRP2,PHC2,HEYL,GPR61,GOLGA7,EIF5,EIF1,PLEKHO1,EPB41,CDHR1,MRVI1,FGF1,ANKFY1,DCTN2,AKAP3,GPR153,GABRA4,GALC,GFER,RNPS1,GSTM5,IL1RAPL1,KAT7,ATOH8,NXPH3,HMGCR,DOCK7,KCNA6,KCNJ3,LIFR,LSAMP,MATN2,MBNL1,MMP16,MOV10,GIT1,MYO5A,PABPC1L2A,NAP1L1,OPRL1,PAK3,PDE2A,PDPK1,PFKFB3,SDK2,PPP2R5E,PRKAB2,RAD51D,DPF2,GTDC1,NUDT11,ATXN7,SCN2B,SCN8A,PEAR1,GALNT10,AMBRA1,FAM126B,LHFPL4,HECW1,ARHGAP26,DBNDD2,EPB41L3,PHLDB1,CLASP1,PSD3,AP4E1,CBX5,PIK3R5,RBFOX2,FNDC5,CLIP2,EVI5,PIANP" MicroRNA hsa-miR-3183:mirSVR_highEffct hsa-miR-3183:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.29E-48 1.29E-44 7.15E-48 6.58E-47 158 816 "CLK4,CSMD3,BRAP,KIDINS220,SLC24A4,TNRC6C,USP37,SFMBT2,STX16,ADAM23,BARD1,FGF17,ARHGEF7,LINC00906,PTBP2,ZNF501,ZMYM4,CHGA,CNOT8,NRXN1,CLTA,DNAJB5,ARMC8,COX4I1,SEC31B,C2CD2,SH2B1,MICAL2,GALNT9,SOCS5,CCDC144A,GAPVD1,PITPNC1,ZEB2,DDX46,ALKBH8,SNAP91,RABGAP1L,RAB39B,GNE,FAM78B,DNM1L,ABCC9,EDN3,EDNRB,EGFR,KMT5B,EPHB1,ENPP6,ETV1,TLR7,EXTL2,RACK1,PRMT5,ZNF589,CSPG5,DOT1L,NRG3,GABRB1,BRPF3,B4GALNT1,RUNDC3A,BRD8,MAP7D2,ADGRA3,TDRKH,LILRA2,GRIA2,ADAMTS8,CLASRP,RNFT2,MAP4K5,UBE2QL1,HNF4G,IRF8,IGF1,KIAA1755,PLD5,IGSF1,SCIN,KCNN2,LIMS1,PIK3AP1,COL28A1,TAGLN3,MTR,MXI1,NF1,PCBP3,GDAP1L1,ANKRD16,MAPKAP1,RC3H2,EPB41L4B,CRLS1,MAPK4,GRAMD1C,HYDIN,BDNF-AS,PTPRB,SLC25A48,FEZF2,SLC6A15,RGS7,RLBP1,RIC8B,CCDC82,EPHA10,MIR124-2HG,ATXN7,LRRTM4,SMPD3,SUPT20H,CPEB3,CNKSR2,PAAF1,RUFY2,SLC22A4,RCOR3,IFT122,LIMCH1,SNCA,CMTR2,SNRPN,ZCCHC24,SP4,KDM4C,NXT2,AJAP1,PLCB1,CAMTA1,UNC5D,FBXW11,SYNE1,NAT16,TGFBR3,SLC44A1,FBXL16,BHLHB9,RGMB,SYNPO2,METTL3,STXBP4,UBE3A,TOM1L2,VLDLR,WIPF1,XPO1,ZNF74,ANKS1B,PLPPR5,CA10,PRDM2,ADAMTS9,PPP1R3F,PDSS2,CASC15,SLC4A10" MicroRNA hsa-miR-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-48 1.36E-44 7.54E-48 6.95E-47 169 921 "ACTN1,ARID1A,ADAR,FMNL2,ERMN,AP1B1,ANK1,PI16,API5,SHTN1,MIER1,ASPH,ATP6V0A1,SEC11C,HCN2,BMP7,FUBP1,AP1M1,CACNA2D1,CALM1,PTBP2,CAMK2G,CAST,FMNL3,RGN,CDC42,CDH2,LRWD1,CLCN3,CLTC,CNN3,BAG4,CDC42BPB,RBM39,AKAP12,RIMS4,PLXNA4,RIMS2,EDRF1,HDAC4,MATR3,IST1,DBN1,YTHDC1,MYEF2,HP1BP3,KLHL3,ZC3H11A,GSDME,POM121,G3BP2,RABGAP1L,SEC16A,RAB39B,E2F5,EDN1,HIPK3,EGFR,ABI2,GOLGA7,EIF4G1,RGS17,BSCL2,MFSD10,EPB41L2,COQ7,DMTN,RABEPK,SRRM1,IP6K2,SEMA4D,FLNC,ANKFY1,NELFCD,ZBED3,STAMBP,NPTN,FYB1,BRPF3,MTHFD2,GLI2,RAB30,ZNF638,KDM2B,FERMT2,GPD2,NUDT21,EML4,RABL2A,PSIP1,NXPH2,MAN1B1,DDX19B,IGF1,TUBB2B,KCND1,KIF2A,L1CAM,LIFR,LIMS1,PAXBP1,MOBP,MOV10,ERICH3,NBL1,RCOR2,CHAMP1,OXTR,GPR137C,CDK14,ABCB1,PSAT1,EPB41L4B,SYTL2,PTPRD,PLEKHB2,SH3TC2,PRIMA1,C12orf49,WLS,ZNF568,SCN3A,SOX6,TRA2B,COPZ1,FAM102A,MYO18A,FNDC3A,FAM81A,PPP4R3A,SLC8A1,TTC17,TMCC1,USP33,SOX5,TROVE2,LARP4,NXT2,MPRIP,FGD4,SYNE2,SYPL1,FAM208A,TRIM2,SYNE1,HIF3A,SLC44A1,CBX5,TLR4,LRRC8A,TPD52L2,TPM1,TPM2,TPM3,TPM4,WBP2,DOK6,ZNF384,TRPS1,SGK3,UBTF,UGT8,PLEKHH2,TRIM9,AMZ1,FTSJ1,HPS4,HNRNPA3,NETO2" MicroRNA hsa-miR-185-5p:TargetScan hsa-miR-185-5p TargetScan 2.51E-48 1.41E-44 7.82E-48 7.21E-47 89 264 "ASIC1,CSMD2,PTCHD1,PCDH10,APP,PRX,DNAH17,ATP1A3,MTMR9,BCL2L2,BSN,CAMK2D,SCARB1,DGKI,CDC42,KCNAB3,GPR37L1,DLGAP3,ABCG1,RIMS4,NRSN1,ARHGAP32,PHYHIP,DGKB,PITPNC1,HP1BP3,C2CD2L,KLHL3,DLG2,DNM1,CALN1,DRP2,E2F6,GPR61,PLEKHA1,ELAVL3,MTSS1L,ERBB2,CORO2B,ANKFY1,INPP5K,FAXC,GPR75,GPR12,GPR26,KAT7,FAM222A,PADI2,KCNC2,KCND3,KCNN3,LSAMP,MAT2A,MDM4,PPM1L,MSI1,NFIX,PBX1,PILRA,PKIA,PTPRG,DPF2,PRRT2,RIC8B,RORB,MYO18A,FAIM2,NMNAT2,KIF1B,ELOVL4,PHLDB1,FAM168A,CNTN2,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HIF3A,CBX5,FNDC5,CADM1,OSBP2,CA10,EVI5,CAMK1G" MicroRNA "AGCACTT,MIR-520B:MSigDB" "AGCACTT,MIR-520B:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-93:MSigDB" "AGCACTT,MIR-93:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520C:MSigDB" "AGCACTT,MIR-520C:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302A:MSigDB" "AGCACTT,MIR-302A:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302C:MSigDB" "AGCACTT,MIR-302C:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302D:MSigDB" "AGCACTT,MIR-302D:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-302B:MSigDB" "AGCACTT,MIR-302B:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520A:MSigDB" "AGCACTT,MIR-520A:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-526B:MSigDB" "AGCACTT,MIR-526B:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-373:MSigDB" "AGCACTT,MIR-373:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520D:MSigDB" "AGCACTT,MIR-520D:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-520E:MSigDB" "AGCACTT,MIR-520E:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA "AGCACTT,MIR-372:MSigDB" "AGCACTT,MIR-372:MSigDB" MSigDB 2.85E-48 1.60E-44 8.80E-48 8.11E-47 97 317 "MTUS1,OSBPL8,AK2,SPOP,ANK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,CFL2,TAOK2,KMT2C,ZNF385A,C2CD2,CREB5,ARHGEF10,HDAC4,TOX,RASSF2,MAML1,IP6K1,PLEKHM1,MFAP3L,KLHL3,DMTF1,DRD1,E2F5,EDNRB,MBNL2,KMT5B,PAN3,ETV1,DNAJC27,MED12L,SUCO,FLT1,ZMYND11,KLF12,HLF,SCRT2,OLFM3,KCNMA1,NCOA7,MEF2C,MYCN,NEUROD1,NFYA,OPCML,PRRX1,KANSL1,MAPK9,SLC22A23,RALGDS,OXR1,ARID4A,RIC8B,ATXN1,FBXO11,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,MYT1L,IQSEC2,CDK19,NPAS3,LMO3,RGL1,CAMTA1,TAL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,DDHD1,ZFP91,NR2C2,TRPS1,VLDLR,DPYSL5,SYNC,EMSY,RGMA,PRDM8,NELFE,FAM13C,MARCH8,PAK5,CERS6,FAM219B,ST8SIA2" MicroRNA hsa-miR-4254:mirSVR_highEffct hsa-miR-4254:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.12E-48 1.75E-44 9.64E-48 8.88E-47 132 586 "RALGAPA1,KCNH8,SORCS1,BEND6,AP2A2,CARNS1,ZNF687,UPRT,NT5C3B,ARNTL,MARK4,NCOA1,SLC4A4,ATP2B2,CADM3,SYNJ1,CALB2,KALRN,CERS5,LGI1,CHRM1,PLAA,CLCN4,CLTA,NIPBL,AKAP7,LETMD1,SLC4A8,GDA,SNCAIP,CSF2RA,CYBB,FRMPD4,KIAA0586,ZBTB24,EXOG,DMD,DPP6,DNM1L,PHC2,SYT15,GOLGA7,C3orf18,EN2,KCNMB2,ANKRD13B,SRRM1,IGSF6,MRPL10,RCSD1,TUBB3,IP6K2,STAU2,GAD1,ZMYND11,DISC1,DNER,TUBGCP4,SULT1C4,PCDH11X,DCLK2,GNAS,TDRKH,STMN2,GRIK3,LINC01089,GABARAPL2,C2orf72,SOWAHA,LIX1,KIT,KLC1,NCOA7,KCTD6,MOBP,MYO7A,DNHD1,SLC11A2,OPHN1,PAH,PCDH9,PCSK5,PFKFB3,PLCL1,RC3H2,POU6F1,PPM1B,PKIA,VPS13C,WDR25,OCIAD1,TMEM145,CCDC40,DBX2,TRIM68,CARF,RXRG,FHOD3,NUBPL,ZNF365,SLC14A1,ELMO2,SPHKAP,GKAP1,ANKRD36,KDM4B,SON,HECW1,SRPK2,ITPRID2,STX1A,NUDT10,TBCEL,ZFP90,SYNE1,SLC44A1,C5orf64,RGMB,PPIL6,RUSC1,TSN,OSBP2,VLDLR,SLC26A10,CA10,STMN4,STOX2,ADAMTS9,C12orf4,CAMK1G,TIGD6,FXR1" MicroRNA hsa-miR-1208:PITA hsa-miR-1208:PITA_TOP PITA 3.36E-48 1.89E-44 1.04E-47 9.55E-47 95 304 "CSMD3,ADAR,ADD3,PTCHD1,OSBPL8,ALCAM,FAM135A,OGT,MIER1,ASTN1,ATP2B1,FUBP1,CAMK2D,CDH2,CACNA2D2,FOXN3,CHN1,HECTD1,MAP4K4,ARHGEF6,ARMC8,BTF3L4,FAM171B,SOCS5,ERC2,PLCXD3,USP6NL,HDAC4,KCTD8,CHRDL1,GRIN3A,CPEB2,DPYSL2,ABCC5,RBM12,EPB41L1,EPHA5,ZIC4,FGF13,AHCYL1,JPH4,GAP43,PCDH17,GPR22,FRMD3,MIER3,ZNF546,KCND2,KCNK2,LDLRAD3,MEIS1,MXI1,GPR137C,GPR85,ANKRD16,STRN3,FAT3,RELN,PTCH1,ZFHX4,RAVER2,ROBO2,LGR4,SALL1,SEMA6D,ATXN1,TRA2B,PPP1R9A,FNDC3A,SLC1A2,BTBD3,SLC8A3,CCDC88A,CPEB4,SNAP25,MBD5,MYT1L,POGZ,ITPRID2,ARHGEF9,CAMTA1,CAMSAP2,MGRN1,CUX2,RIMBP2,UBE3A,ZIC3,LYPD6,TCEAL7,ZBTB38,CADM2,NAV3,HNRNPA3,FRMD6,ST8SIA2" MicroRNA hsa-miR-519e:mirSVR_highEffct hsa-miR-519e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.74E-48 2.10E-44 1.16E-47 1.06E-46 139 647 "CLK4,NCKAP5,KLHL32,ADCY6,KIAA1324,SMIM17,ARHGAP20,OGT,ANK3,PPFIA2,PPFIA1,LGR5,ASPH,ATP1A2,ADAM23,ST3GAL5,SGCE,CA4,CACNA1D,LRRFIP1,RCBTB2,SRSF11,CHGA,JAM2,COG1,C4orf33,ARMC8,AKAP6,CLOCK,CS,PDE4DIP,CFAP61,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,BLOC1S6,SNAP91,DLG2,NR1D2,ABI1,PDCD6IP,DNM1L,GOLT1B,PHF20L1,MRNIP,DCTN4,VPS13B,EPB41,EPB41L2,ENPP6,EXTL2,WAC,FGFR1,SUCO,HPCAL4,JKAMP,TMEM107,UFM1,STAG2,GABRA3,IQGAP2,KIAA1841,USP19,RND1,RAB30,GLS,GRIA4,NR3C1,SOX21,PSIP1,IGSF21,HSPA1L,HSP90AA1,HTR5A,ZNF678,KCNC2,LMO2,MAT2A,MBD1,ZNF680,MRPL42,ZNF92,MYO6,NCAM1,SFR1,NF1,NOVA1,HCN1,NUMA1,CDK18,PRTG,MTRF1L,RETREG2,BDNF-AS,PXK,PTPRB,PTPRG,FAT4,RASGRF2,SLC6A15,CYB561D1,CSRNP3,HSPA4L,NTNG1,CNKSR2,DZIP1,ANKRD6,NUBPL,BTBD3,DHX30,CMTR2,KIF1B,ITPRID2,SSTR1,NECAB1,SYT1,ANKRD28,CAMTA1,MCF2L,SATB2,TCF12,SYNE1,DOCK9,PUM2,SIK3,HHIP,NPL,ANKRD20A2,WIPF1,P2RY12,SMARCAD1,DHX33,EMSY,DNALI1,LINC02210,UBE3B" MicroRNA hsa-miR-1976:mirSVR_highEffct hsa-miR-1976:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.84E-48 2.16E-44 1.19E-47 1.09E-46 134 604 "ARID1A,SNX32,KIF6,SUGT1P4-STRA6LP-CCDC180,APP,PPP4R4,MARK4,TTLL9,RGS11,CBR1,AIFM1,CDH8,DIS3L,AKAP6,BAG4,CREM,NCOR1,CSF2RA,FEZ1,CSNK1G3,PHACTR3,CTH,RIMS2,CYBB,CENPL,SV2A,DLG2,USP3,KCTD3,GPHN,ECSIT,NRN1,F3,SCML2,GTF2IRD2,SPSB4,POLK,GHDC,GAP43,KIAA1841,TXNL4A,STARD3,LUZP2,LOXL3,PCLO,RAPGEF1,FAM19A2,FRMD5,HSP90AA1,RBPJ,DISP2,GPR62,KCNJ3,PACRG,GPR155,ZNF667-AS1,AQP11,MATN2,SYT9,MDM4,MEIS2,MMP16,CD200,MTR,RSPO2,CCDC13,NFE2L2,PBX1,PRTG,PDE4D,GNG2,HMGCLL1,PRRX1,RETREG2,SEPT4,MED1,LRRC49,PSMD13,ZSCAN32,CCDC40,OXR1,RFX4,SETD5,CARF,TMEM156,LINC00461,GALNT10,FERMT1,CTXN2,PPP4R3A,SLC6A11,MAST1,RCOR3,IFT122,ANKRD36,MBD5,ZSWIM8,ZC3H13,RBM26,MPRIP,KANK1,SULF2,STXBP1,NECAB1,TACC1,PJA1,ROBO3,TBCEL,MGRN1,TCF7L2,NAT16,ARHGAP9,HIF3A,AP4E1,AKTIP,R3HDM1,KAT6B,TPM1,ZMYND8,PPIL6,EIF4ENIF1,FLRT1,USP1,ZNF709,CCDC136,ATP6V0E2,ZNF138,PLPPR5,MEIS3,EMSY,NAV3,FIP1L1,CASC15,CAMK1G" MicroRNA hsa-miR-129-3p:mirSVR_highEffct hsa-miR-129-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.99E-48 2.80E-44 1.54E-47 1.42E-46 125 530 "ACADM,ACLY,XKR4,NDRG2,FMNL2,KIDINS220,KLHL13,HFM1,LRRC7,CACHD1,NAE1,BTK,JAZF1,PTBP2,USP6,TMEM257,DGKI,HECTD1,COL9A1,LETMD1,ABI3BP,COX4I1,RBM39,VAC14-AS1,CTNND1,DOCK4,TOMM20,SPATA2,RHOBTB1,SACS,GOLT1B,E2F5,FAM135B,PHF20L1,RCAN2,RTN3,F5,ZSCAN30,MED12L,POLK,CAP2,NOP56,AKAP3,NPTN,GABRA1,JPH4,DISC1,WASF3,CECR2,GRIK4,GRIN2D,PRDM5,FRMD3,DOCK7,LIX1,DIPK1A,KHK,KIF5A,PAXBP1,HECTD2,PIK3AP1,IL17D,MMP16,MYO9A,NINJ2,GPR137C,GLIPR1L2,PDYN,TRHDE,PKIA,PKN2,GDPD2,MTMR10,SPDL1,ERI2,RFX3,RGS12,SUGCT,CCDC102B,TMEM100,BAALC,TCP11L1,MEG3,RTKN,RYR3,NCBP3,LINC00461,CASC3,FRMPD1,ABLIM3,DHX30,SLC8A3,SLC9A5,RIMS1,SON,BDP1,ATP10B,CLASP2,COLGALT2,SS18,ERBIN,GSE1,SYT4,ANKRD12,CAMSAP2,TMEM136,TCF7,SLC19A3,FRYL,PMS2CL,CRB1,TIAM1,HEY1,TNR,TPD52,TRIO,TRO,RPL7L1,FAM155A,FLRT2,PRDM2,PRDM8,PLSCR4,PHTF2,LAS1L" MicroRNA hsa-miR-513a-5p:PITA hsa-miR-513a-5p:PITA_TOP PITA 5.83E-48 3.27E-44 1.80E-47 1.65E-46 88 260 "ASIC2,CCDC85A,ADD3,SORCS1,USP31,UNC5A,RTL9,LRRC7,LCORL,CDC14B,SYNJ1,CACNA1A,RUNX1T1,ZMYM4,CFL2,SOCS6,QKI,CNR1,CRY2,PPP1R16B,CTNND1,MAGI2,SMG7,SRGAP3,DPYSL2,MAMLD1,CELSR3,ELAVL2,EPS8,ERBB4,EYA1,MEX3B,AGAP2,EVL,USP21,NPTN,TBR1,CHL1,PPARGC1A,PSRC1,GRB10,C1QL4,MAP4K5,KLF12,MIER3,AGFG1,C5orf24,KCND2,MARK1,ADAM11,CHIC1,ERICH3,PCSK2,TMOD2,PDZRN4,POU3F2,WBP1L,SNRK,PEX5,USP47,FAM184A,ALG9,SCG5,PPP1R9A,SH3GL3,PPM1E,SLC1A2,MYCBP2,NPAS3,SS18,ARHGEF9,SYP,SYT1,MTCL1,UNC5D,EHBP1,KIAA0930,TRIM2,HHIP,TRPS1,SSBP2,MAP3K12,EMSY,PDSS2,KAT6A,JMJD1C,RNF146,CBLN2" MicroRNA hsa-miR-2909:mirSVR_highEffct hsa-miR-2909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.07E-48 3.97E-44 2.18E-47 2.01E-46 114 444 "RALGAPA1,NBAT1,KLHL32,ADD2,KIAA1211,RNF150,HECW2,ALCAM,ABCD2,AMPD3,LCORL,ZFYVE28,ADAM23,CACNB2,SYT6,RUNX1T1,LRBA,SRSF11,CASC2,RGS6,CTNND1,RIMS2,FRMPD4,ZEB2,ZBTB24,KLHL3,CHRDL1,DLG2,WDPCP,RASGRP1,EGFR,AASS,MRNIP,EIF1,ERBB2,TUBB4A,DLC1,SLC9B2,SEMA4D,AKAP3,SMC2,SARAF,TBR1,AP4B1,NRG3,MEGF11,GABRA2,GATM,TOX3,ZNF638,DCLK2,LNX1,SOX21,RASSF8,DHX35,HTR2A,KCND1,MAT2A,MBNL1,COL28A1,RSPO2,NRCAM,TBC1D25,PDE3B,PIRT,PDGFRA,GPR85,BEST3,PLP1,SEPT4,EPDR1,VPS13C,SLC22A23,SIDT1,PTPRD,PEX5,ZNF615,NWD1,MSANTD2,RFX5,NUDT11,ATP8B4,ACER3,NCBP3,KANSL3,MYO16,SON,BDP1,TAB2,NKAIN2,UNC5D,FBXW11,VWA3A,ZFP90,WASHC4,NAT16,PCDHB4,PUM2,TEX15,SIK3,TJP1,TLL2,KAT6B,RUSC1,SSBP2,RFTN2,CADM1,BEST1,CELF4,PCDH15,SNX27,CASC15,CBLN2,SOCS4" MicroRNA hsa-miR-4324:mirSVR_highEffct hsa-miR-4324:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.03E-48 4.51E-44 2.47E-47 2.28E-46 139 651 "KCNH8,AS3MT,NDRG2,ADD2,MTUS1,BIN1,APBA2,BCAS1,API5,MIER1,TMEM263,ZFYVE28,ARNTL,ATM,B3GALT2,DOCK11,CACNA1E,CAST,CDH8,MAGI1,CHM,CASC2,PPT2,ABCG2,SULT4A1,ARMC8,COX4I1,IGDCC3,CREM,TENM4,PHF14,CFAP61,DAPK1,DBI,GIT2,PITPNC1,ZEB2,SGSM2,RABGAP1L,RAB39B,DMPK,CPEB2,DMTF1,ECM2,ABCC5,SRRM1,IGSF6,ZNF549,NRN1,SCML2,ATP8A1,TOMM40L,ZNF589,FGF13,SEMA4D,TMEM107,GAB1,SIGLEC8,CPLX1,NEU3,TXNL4A,TCERG1,ZNF638,CBX1,EML4,STMN2,GRIA2,PRDM5,FAM19A2,HNF4G,SMAP1,NKD1,SLC35G1,KCND1,KCNN3,HECTD2,MARK3,MAT2A,CHIC1,MIA2,ERICH3,SLC11A2,CHAMP1,PDE4D,HMGCLL1,POLR2F,DRAM2,MAPK8,APTX,PTK2,TMEM260,OCIAD1,FAM66C,RASGRF1,GTDC1,RGS10,KCTD17,KIF7,ZFHX4,CCDC82,ZC3H14,LGR4,MEG3,ASIC4,SELL,SH3GL2,PPP4R3A,SLC14A1,ANKRD36,SNRPN,UNC80,SOX5,BDP1,GLT8D1,KDM4C,ATP10B,STAC2,VPS13A,CAMSAP2,UNC5D,TBCEL,WASHC4,PCDHB4,MTMR14,TPD52L2,NPL,AMACR,TSN,RFTN2,CADM1,LINC00689,KLC2,ZIC3,TRIM9,PLPPR5,PCDH15,WIPF2,EPM2A,NETO2" MicroRNA hsa-miR-33a:PITA hsa-miR-33a:PITA_TOP PITA 8.07E-48 4.53E-44 2.48E-47 2.29E-46 83 230 "SLC25A25,FMNL2,SLC12A5,GPR158,UNC79,CDC42BPA,DPP10,ANK3,B3GALT2,CAMK2G,USP6,LGI1,FOXN3,CHN2,KIAA1549L,MAP4K4,GDA,SEC24C,ST18,ZFYVE16,ZEB2,WDR20,DLG4,RCAN1,CNNM1,EN2,ATP8A1,OLFM1,AFF2,SALL3,MSTN,GHR,PPARGC1A,SPIN1,HTATSF1,GPD2,BACH2,KCNA4,KCNMA1,MARK1,MEF2C,MEIS2,NFIX,NPY,NOVA1,GPR88,PDGFRA,ENPP2,XRN1,PCDH18,PACSIN1,PPP3CA,PPP3CB,DIRAS2,SLC6A15,FBXW7,SCN8A,CASC3,GALNT10,CPEB3,SLITRK3,WDR47,SOX11,ENKUR,ERC1,SYT11,VPS13A,TCF4,SATB2,WASHC4,RIMBP2,CSMD1,TNS1,TPM3,TRPS1,KCNE5,TBC1D15,DPYSL5,NAV3,WIPF2,SLC17A6,GOPC,SLC4A10" MicroRNA hsa-miR-3131:mirSVR_lowEffct hsa-miR-3131:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.64E-48 4.86E-44 2.66E-47 2.45E-46 120 492 "RALGAPA1,DGCR6,NBAT1,XKR4,ADAR,AP2A2,TBC1D14,ZNF687,MAP4K3,TNRC6C,MADD,SLC4A4,CARMIL3,ADAM15,LINC00847,CACNA1B,CACNA2D1,THSD7A,KALRN,LGI1,TIGD7,CHN2,CLCN3,TJP2,PICK1,FAM149A,AKAP6,CNTNAP2,PNPLA8,DCAF4,ZNF337,NTM,TMCC2,DYRK1A,EDN1,EDNRA,EFNB3,OLIG2,ANKRD13B,RTN3,TUBB3,ATP8A1,NOP56,TMEM175,STAG2,MEGF10,SULT1C4,CRCP,HTATSF1,LILRA2,CECR2,GRIA2,IL1RAPL1,FRMD3,ATXN2L,ACOT7,CPT1C,MYLK2,SOWAHA,SLC35G1,KCNC2,TTYH2,LMO1,AQP11,TM6SF1,MOBP,PTOV1,TAGLN3,PABPC1L2A,NCAM1,NFIX,NTRK3,PCMT1,NLE1,PLXNB3,MAPKAP1,PPP2R5C,RAB39A,PIGG,UHRF1BP1,PTPRB,PTPRG,FEZF2,SLC25A36,ZNF532,CARF,RPE65,SATB1,CSRNP3,FAM19A1,ASRGL1,SH3GL3,ST3GAL3,SEC31A,ZNF430,SLC12A4,CPEB4,LHFPL4,POGZ,STAC2,KANK1,SYN1,SYT4,KAZN,PDLIM2,ANO4,SIN3B,ERCC6L2,TNFRSF1B,RUSC1,TTTY15,UCHL1,PLPPR2,ANKS1B,CSDE1,CIAPIN1,SEMA3B,SLC17A6,UBE3B,DPF3" MicroRNA "GCATTTG,MIR-105:MSigDB" "GCATTTG,MIR-105:MSigDB" MSigDB 9.55E-48 5.37E-44 2.94E-47 2.70E-46 71 163 "OGT,PHF12,NCOA1,ARHGEF7,FOXK1,KALRN,CAMK2G,CDH2,NRXN1,CREB5,SOCS5,SLITRK5,KIAA0408,CCDC3,GOLT1B,ST8SIA3,PHF20L1,EIF4G2,COPS4,PAN3,ETV1,EXTL2,NSRP1,AMOTL2,NBEA,SPECC1,CELF1,GABRB3,GAD1,COPS8,GLDC,GRID1,KLF12,GABARAPL2,HNRNPK,HTR2A,IGF1,LDLRAD3,MEF2C,MXI1,ZDHHC22,PDE1B,GPR85,CDK14,KANSL1,PTPN13,PTPRG,RAD52,ZNF532,MRAP2,FAM19A1,SOX6,TRA2B,FNDC3A,CXXC4,FAIM2,SON,SP4,TEX2,ARHGEF9,SATB2,DICER1,TJP1,TPM3,AMOT,FLRT2,ZIC3,CA10,PRDM2,PRDM8,SSPN" MicroRNA hsa-miR-1470:mirSVR_lowEffct hsa-miR-1470:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-47 5.65E-44 3.09E-47 2.85E-46 116 461 "ACADM,NCKAP5,CSMD2,PLEKHG5,ADORA1,SPOP,ATM,MYOM1,BCL7A,BTK,GYG2,CDK5R2,MMD2,TRIM41,BRSK2,LARGE1,MAGI1,MYL6B,SULT4A1,SEC31B,NCOR1,MICAL2,PHF14,NRSN1,DAPK1,LYPD1,SMG7,SRGAP3,KIF19,DLX1,DNM1,USP3,DNM2,TOM1,APH1A,EGFR,SORBS3,ING4,C3orf18,EMX2,EPB41,SUCO,SEMA6C,FLT1,TMEM107,CGREF1,NRG3,ZMYND11,ARPP21,STMN2,DIDO1,C1QL4,ADAMTS13,GRM5,BVES,RASSF8,NXPH3,AGBL5,KCNB1,MAG,ADAM11,MDFI,LRP1B,SCAMP5,MYO7A,NTRK2,PDE2A,PDE3A,PDE4A,SERPINE2,ZFYVE21,TNPO2,SH3KBP1,BCAS3,WBP1L,PTPRH,RALGDS,FAT4,RIC8B,UEVLD,S100B,SCN2A,SCN8A,FOXRED1,SLC1A6,ARFGAP1,SMARCE1,RCOR3,MBD5,FAM219A,SON,ZSWIM8,SPTB,SRPK2,ITPRID2,SSPO,GANAB,VAMP1,ADGRL3,NSD1,TNS2,TNR,PIK3R5,TPD52L2,PRMT8,UBE2H,USP1,VAV2,WIPF1,GUSBP1,XRCC4,PRTFDC1,SEMA3B,UBE3B,PHTF2,FXR1" MicroRNA hsa-miR-615-3p:Functional MTI Functional MTI miRTarbase 1.24E-47 6.96E-44 3.80E-47 3.50E-46 165 893 "SDE2,ABCF1,RBM10,ACTN1,PLEKHG5,CDC7,PWWP2A,ZNF687,SEMA7A,EP400,USP28,APBA2,ARRB2,CCAR2,ATP2B1,DST,FUBP1,FOXK1,CANX,CBS,SCARB1,ENTPD6,LRBA,LONRF2,CDH2,ARHGAP22,KMT2C,ZFYVE9,CLTC,MAGED1,NCOR1,SEC24C,CHD5,CTNND1,GPSM1,ZFYVE16,MATR3,INTS1,SIRPA,DBN1,FAM107B,SEC16A,DLG3,DNM1,DNM2,ATN1,DNM1L,FAM135B,FAM13A,ASB3,EIF4G1,MTSS1L,EZH1,TUBA1B,CHST15,KIAA1109,SCARA3,FOXO3,APOPT1,PRELID3A,PNMA2,SARAF,SALL3,GART,SRCAP,USP19,TCERG1,RNPS1,GLUL,GNAS,PRRC2B,RAPGEF1,DIDO1,CACFD1,BVES,ARHGAP19,BACH2,MIER3,HMGCR,HNRNPK,CPT1C,IDH3B,IL6ST,TUBB2B,ITGA7,KIF2A,NAT8L,ZFYVE27,MBD1,AFF1,MOV10,MPP2,MXI1,MYO9A,NACA,HNRNPM,NPTX1,NRDC,NTRK3,CHAMP1,OGG1,PFKP,SSH1,PKD1,PLEC,SMOX,LRP12,MBOAT7,TNPO2,POLG,PPP5C,PRKAB2,EPDR1,WBP1L,PSMD13,RAB5B,PLEKHB2,RAD51D,RALGDS,BSDC1,RFX3,KLHL11,MYH14,RAVER2,KIRREL1,RPL15,SOX8,SFPQ,SUPT20H,SHMT2,EPN2,SEPHS1,RADIL,SMARCA4,SMARCC2,KDM4B,FNBP1,NMNAT2,GANAB,RHBDL3,DNAJC9,SYPL1,TAF6,EXOC7,NSD1,PUM2,ATP13A2,AKTIP,TIAM1,TJP1,TMPO,BEX4,CDK20,TPM3,NR2C2,TRPC1,UBC,RPL7L1,NSD2,ZNF711,POLR3H,WNK1,RGMA,TUBA1A,SOCS4" MicroRNA hsa-miR-1200:PITA hsa-miR-1200:PITA_TOP PITA 1.35E-47 7.60E-44 4.15E-47 3.82E-46 101 350 "PWWP2A,HECW2,OSBPL8,ZNF687,TMEM263,DOCK11,BCL2L2,BCL7A,ARHGEF7,MTMR3,CALM1,LDB2,FMNL3,L3MBTL4,SLC4A7,IGDCC3,PLCXD3,CTNND2,FRMPD4,ZFYVE16,TM9SF4,PITPNC1,FAM107B,ARRDC4,PHC2,FAM13A,ABI2,EML1,PAN3,EPB41,NRN1,TOMM40L,SORBS1,SRRM4,WASF3,PCDH17,TTBK1,TNRC6A,KDM2B,LOXL3,EML4,PCLO,KAT7,LINGO1,BACH2,DHX35,SLC35G1,L1CAM,MARK1,CHIC1,MIA2,MYT1,SLC11A2,KSR2,PDE3B,PDE4B,PDE4D,ANKRD16,PKN2,CNNM2,UHRF1BP1,PTK2,FAM120C,FIGN,ZFHX4,ALG9,LGR4,SMPD3,SOX6,KIF21A,SH3GL2,PPM1E,KIF16B,AMBRA1,FBXO11,FAM81A,FAM214B,YPEL4,SMARCE1,SOX11,GLT8D1,CAND2,MYCBP2,ZSCAN29,STAC2,SYP,CAMTA1,CAMSAP2,UNC5D,RPGRIP1L,WASHC4,DOCK9,AHCYL2,TMEM121,AP4E1,RELL2,RBFOX2,TPD52L2,AMOT,ZIC3,WIPF2" MicroRNA hsa-miR-624:PITA hsa-miR-624:PITA_TOP PITA 1.79E-47 1.00E-43 5.48E-47 5.05E-46 90 276 "ABR,PCDH19,OSBPL1A,OSBPL8,DPP10,ATP2B1,BSN,CACNA1A,USP6,ZMYM4,SOCS6,QKI,GDA,TENM4,ERC2,PLCXD3,PUM1,DOCK4,ALKBH8,MAMLD1,ABCC5,ST8SIA3,KMT5B,ELAVL2,TESK2,SEMA4D,NBEA,SORBS1,CELF1,OGA,FYN,MEGF11,GABRB3,CPLX2,GFRA2,PCDH17,NR3C1,NEGR1,IGF1,RBPJ,MBNL1,MPP2,MYCN,NEK1,NTRK3,CHAMP1,OPA1,PDGFRA,CDK14,PLP1,PRRX1,PPP3CA,KANSL1,TMEM255A,ROBO1,ROBO2,AP1AR,SALL1,SEMA6D,ATXN1,SFPQ,ITSN1,CPEB3,ATF7IP,MYT1L,SOX2,FNBP1,SPART,NKAIN2,SS18,TTBK2,SYT11,ANKRD28,MTCL1,EXOC7,ADGRL3,TBL1X,EHBP1,TCF4,SATB2,TRIM2,SYNE1,PUM2,FRYL,FLRT2,ZBTB38,POLR3H,PMEPA1,JMJD1C,VANGL2" MicroRNA hsa-miR-885-3p:mirSVR_lowEffct hsa-miR-885-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-47 1.04E-43 5.68E-47 5.24E-46 153 782 "KDM5D,SLC12A5,ADORA1,UNC5A,AP2A2,DOC2A,PKP4,KCNAB2,UPRT,SLC2A11,DPY19L3,ADAM15,ADGRB2,ARHGEF7,CAMK2A,P2RX6,CDC42,LGI1,CCPG1,CASC2,NDST3,CLU,NIPBL,WHRN,ABI3BP,SMARCAL1,ZNF521,CREM,AATK,MICAL2,PLCH2,PDE4DIP,NRSN1,ST18,LONRF1,ARMCX2,C8orf34,HEPH,COPS7A,DMPK,DYNC1I1,CPEB2,DOCK2,TOM1,KRBA2,TSPAN5,EDN3,EEF1A2,FAM13A,EIF4G2,ELAVL3,ANKRD13B,KAT8,CELF1,SDCBP2,GABBR1,GABRB1,GABRG2,ACSS1,LRRC37A6P,TUBA8,SESN1,C1QL1,GLI2,GNAO1,GNAS,ADGRA3,GP1BB,C1QL4,PLPP7,ATE1,LINC00839,CELF3,DHX35,ATCAY,INSM1,ITGA7,L1CAM,CLEC18A,MBNL1,PPM1L,GIT1,MYO9A,PCBP3,CHAMP1,SNTG1,PAK3,PCDH9,PRTG,GNG2,PFKFB3,PNMA3,C11orf49,PMP22,MAPKAP1,FSD1,PPP1R1A,PPP2R2B,PPP2R5C,PIGG,TMEM260,PEX5,RIPOR1,RALGDS,RASGRF2,ZDHHC14,CRTAC1,RFX4,RNF220,SETD5,SNX22,LGR4,MEG3,TMEM156,FAM192A,SAFB,LINC00461,SMPD3,ASIC4,SEC14L1,TRIM46,SMTN,SLC6A1,ARFGAP1,RCOR3,ANKRD36,LIMCH1,GLT8D1,KDM4C,ZNF423,IQSEC2,CAMTA2,ST5,ADHFE1,EXOC7,TPCN2,SYNE1,HIF3A,LEFTY2,AP4E1,TNS1,RASD2,CDK20,TTC3,SGK3,LAT2,ZNF19,ZNF70,SLC26A10,DNALI1,DOCK8,ST7,SNX14" MicroRNA "CATTTCA,MIR-203:MSigDB" "CATTTCA,MIR-203:MSigDB" MSigDB 2.44E-47 1.37E-43 7.48E-47 6.89E-46 88 264 "ARID1A,NDRG3,FMNL2,ZNF608,PCDH19,OSBPL8,MAP4K3,PHF12,APC,DGKZ,API5,SLC7A14,ARNTL,ATM,SLC4A4,STX16,ATP2B2,BCL7A,SYNJ1,FOXK1,CAPN3,CDH10,ZMYM4,MAGI1,NUMBL,SOCS6,PLAA,CNTFR,PHF19,DGKB,MYEF2,DYRK1A,EDN1,MBNL2,EGR3,EN2,ETV1,FOXG1,NBEA,GABRB3,CAB39,ZMYND11,LRRC37A6P,GLRB,GNAO1,RAPGEF4,ADAMTS6,KLF12,NEGR1,LAMP2,ARHGAP12,SMAD1,MBNL1,MEF2C,NOVA1,PCSK1,PCSK2,PDE4D,GPR85,NXPH1,PPM1B,PRKCB,MAPK9,PTPRG,ZNF532,TMEM100,SLC1A2,YPEL4,SLC12A2,BTBD7,CPEB4,LIMCH1,SP4,NMNAT2,CLASP2,SEPT3,KIAA0930,RPGRIP1L,TCF12,GALNT17,R3HDM1,NR2C2,TRPS1,SGK3,AMOT,SPIRE1,SLC17A6,C12orf4" MicroRNA hsa-miR-580:PITA hsa-miR-580:PITA_TOP PITA 2.49E-47 1.40E-43 7.61E-47 7.01E-46 97 324 "KCNH8,NLGN4X,GPR158,OSBPL1A,LRRC7,DPP10,GPAM,CACHD1,CAMK2A,SEPT7,MAGI1,DLGAP2,FOXN3,CLTB,NIPBL,TBPL1,CLOCK,CSNK1G3,ATRNL1,PUM1,ST18,MAML1,IST1,GUCD1,ALKBH8,RAB39B,PDCD6IP,FRY,KCTD3,TMEM35A,TMEM74,ACSL4,SEMA4D,AFF2,NBEA,ATP6V1H,KIF3A,MAP4K5,KLF12,BACH2,MIER3,AGFG1,HTR2A,KIF5A,MBNL1,MIA2,XRRA1,MRPL42,RSPO2,NCAM1,OPCML,PCSK1,RETREG2,DRAM2,MED1,PPP2R5C,PPP3CA,CEP41,PTK2,PBRM1,ZFHX4,ROBO2,ZC3H14,AP1AR,SATB1,SCN8A,SOX6,CPEB3,SLC6A1,ATF7IP,SPHKAP,TMCC1,SOX5,PEG10,STAU1,RGL1,STAC2,SYPL1,CAMTA1,CAMSAP2,ANO4,TCF4,WASHC4,PSD3,FRYL,DICER1,TIAM1,NR2E1,NR2C2,AMOT,TOM1L2,FMN2,REEP1,SLC17A7,PCBP4,RGS7BP,GOPC" MicroRNA hsa-miR-202*:mirSVR_highEffct hsa-miR-202*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.62E-47 1.47E-43 8.01E-47 7.38E-46 148 738 "ABCF1,ACTN1,KDM5D,KLHL32,ADD2,ERMN,DISP3,C1QTNF3,AMPD3,OGT,PKP4,EPB41L5,ALS2,CACNA1D,INA,LRBA,C4orf33,CNR1,IQCK,SLC4A8,RTTN,GDA,CS,SNCAIP,FEZ1,ARHGEF10,ATRNL1,PLCH2,PHF14,ARHGAP24,DGKB,BRINP1,CEP170,DDX46,ALKBH8,SGSM2,ABI1,DYRK1A,E2F6,SEMA3D,FAM13A,KMT5B,GOLGA7,CALCRL,PAN3,RTN3,ACSL4,CEP78,SLC9B2,FGF12,IQCG,PSD2,STAU2,TBR1,CAB39,GAD1,GDF9,ADAM28,TNRC6A,GPM6B,TDRKH,CECR2,ATP2B1-AS1,MAP4K5,AGBL5,ZDHHC15,HSF2,ZNF181,USP54,HES5,KCNA4,KCNJ3,KCNK1,MATN2,MITF,AFDN,COL28A1,ZNF92,NEK1,SMIM11A,SNTG1,PCSK5,PDCD2,CDK14,PRRX1,MED1,MINDY2,CRLS1,PPP2R5C,CEP41,SNRK,TMEM260,C1orf109,PTPRZ1,TTC13,ZNF493,ZFHX4,PRR5L,ADAL,ATXN7,LRRTM4,STUM,NTNG1,CCDC88A,SPHKAP,PDZD2,MYT1L,KDM3A,KDM4C,RBM26,NFASC,TAB2,TROVE2,ZNF302,EPB41L3,NKAIN2,LRRC4,ERBIN,NEK4,ZC3H4,VPS13A,CAMSAP2,TBCEL,ZEB1,TCF12,TEK,TJP1,NR2E1,HEY2,SYNPO2,RUNDC3B,AMACR,TRPC1,TMEFF2,RPL7L1,AMOT,MICU3,TRIM9,LYPD6,PRDM2,STOX2,ADAMTS9,FIP1L1,SLC17A6,FAM13C,FZD3,VANGL2,IFT88" MicroRNA hsa-miR-191:mirSVR_lowEffct hsa-miR-191:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.82E-47 1.58E-43 8.61E-47 7.93E-46 125 538 "ABR,ASPHD1,SYS1,ADCY8,SLC12A5,KIDINS220,ZNF608,SEMA6A,SYT13,LRCH2,PHF12,CACHD1,MIER1,CASK,EIF4G3,ATP2B2,BBS2,CDK5R1,SCAPER,MYRF,CDK5R2,CALM1,PTBP2,KRIT1,MTMR7,NRXN3,PPT2,NIPBL,CNN3,AKAP5,GDA,EARS2,FBXL5,SACS,SRGAP3,RABGAP1L,FAM107B,GRIN3A,PHC2,FRY,ABI2,CDHR1,RCSD1,GORAB,SEC24B,SLC37A3,PDLIM5,ATP6V1H,ZNF274,SPIN1,GLYR1,RAB30,TOX3,ZNF638,PCLO,GRIK2,GUCY1B1,MAEL,AGBL5,CELF5,IL11RA,BRINP3,OLFM3,TTYH2,LAMP2,LIFR,ARHGAP12,MAP4,MARK3,MEIS1,MSI1,TAGLN3,NELL2,NFIA,NOVA1,DNHD1,NPTX2,CHAMP1,OXTR,PCDH8,TMOD2,PURG,MAPKAP1,TNPO2,PSMD13,ATG16L1,NWD1,ENOX1,RASGRF1,GTDC1,ZNF532,SETD5,PNMA8A,NEK11,GLDN,NCBP3,ZNF331,SCN8A,LINC00461,ITSN1,SHC4,SLA,SLC6A8,SLC12A2,SMARCA4,SOX2,ZCCHC24,KANK1,AJAP1,JMJD6,C3orf70,USP22,ZFPM2,SLC44A1,RBFOX2,TSN,TTTY15,P2RY12,ZIC2,EML6,FAM13C,UBE3B,CERS6,FAM219B,FXR1" MicroRNA hsa-miR-149:mirSVR_highEffct hsa-miR-149:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.94E-47 1.65E-43 8.98E-47 8.27E-46 150 757 "ACADM,ADD1,ADD2,SORCS1,ADORA2A,PCDH19,SRPX,FAM135A,CACHD1,SEMA4G,SLC4A4,SLC2A11,NRP2,GPR146,DDR1,CACNB2,TRIM41,NFS1,CDH2,SOCS6,ASIC3,CASC2,RAB33A,DGCR9,CLTA,TOGARAM2,HINFP,NCOR1,SNCAIP,SEC24C,LONRF1,ARMCX4,MYEF2,KLHL3,RABGAP1L,EXOG,HS3ST2,USP3,DNM1L,EDNRA,FCF1,IRAK4,TNK2,VPS13B,DENND4A,CLVS1,NSRP1,FCGR3A,OLFM1,FLT1,SPECC1,GABRA2,ZNF44,TRAF3IP2,BRPF3,FAM120B,IGSF5,ADAM28,GGT7,STARD3,CBX1,GRIN2C,LINC00839,ARHGAP19,NCKAP1L,SMAP1,ZNF181,KCNJ3,KCNMA1,KHK,KIF2A,ZFYVE27,MAT2A,SRSF12,CCDC80,CTNNA3,RSPO2,NAP1L1,NCAM1,NCAM2,NF1,SLC11A2,NTRK2,NUCB2,OLR1,PAK3,PDGFRA,BEST3,NLE1,PLIN1,PCDHB17P,PSMD13,PXK,PTPRO,FAM120C,RAD51D,MORC4,RGR,ZNF532,ROBO1,RPL15,ATP8B4,YJEFN3,KCNIP1,DGLUCY,CASC3,SH3GL3,SHMT2,CNKSR2,ZNF365,ARHGEF40,NAPB,ELMO2,ZNF667,SORCS3,TSNAXIP1,CLSTN2,ZNF302,ZC4H2,TTBK2,GSE1,POPDC3,EXOC7,ALG1,EHBP1,TCF7,TCF12,FBXL16,BHLHB9,TPM1,CDK20,ELP5,FNDC5,TSN,TSC1,PLEKHH2,CCDC14,WIPF1,SF1,ZNF540,MKRN3,INTS3,PRDM2,PRDM8,PRDM10,CIAPIN1,PCDH15,AMN1,JMJD1C,ZNF248" MicroRNA hsa-miR-363*:mirSVR_highEffct hsa-miR-363*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.63E-47 2.04E-43 1.11E-46 1.02E-45 135 624 "RALGAPA1,SLITRK1,CCDC85A,BEND6,OSBPL1A,ADGRF5,SEMA6A,PCDH10,FAM135A,ANK3,PHF12,FAM131A,PHYHD1,AQP4,MIER1,ALDH4A1,CHID1,MPDZ,NRP2,CACNA1B,LURAP1,KALRN,CAST,BRSK2,AP4M1,CDC42,ZMYM4,CDH18,DLGAP1,CCPG1,DNAJB5,COL9A2,SLC4A7,CPS1,SH2B1,LRRC3B,PDE4DIP,RASGEF1C,HDAC9,TM9SF4,DBN1,DCC,ARMCX2,ZEB2,ELMO1,HS3ST2,ACOT8,DTNA,MAMLD1,EBF1,EDNRA,SGK2,SYT15,RBM12,EGFR,TNK2,EPHB1,ABCA8,ACSL4,DLC1,ZMYND10,FER,FGF12,AMOTL2,POLK,NELFCD,TBR1,ZNF512,ZMYND11,ERAP1,ZNF559,LYVE1,PSRC1,MCHR1,PCLO,DIDO1,GRM1,GRM7,ZNF496,LRRC25,IL11RA,ZNF678,CAMK2N2,INSYN2,VWA5A,MBNL1,LDLRAD3,MDM4,NELL1,CCDC13,NPY,NOVA2,OLR1,ZNF827,ST8SIA5,RC3H2,CNNM2,SYTL2,CCDC40,RAP1GDS1,EXD2,C12orf49,CCDC25,TCP11L1,FNIP1,SLITRK3,ZNF365,SLC6A1,TET1,SORCS3,KIF13A,KDM4C,PBLD,TROVE2,SYNE2,SYN1,SMG6,ANO4,SYNE1,AKNA,USP32P1,HIF3A,SIK3,CRB1,PRRT1,TPM2,TPM3,ZNF384,ELP5,EMSY,MFF,CIAPIN1,SIGLEC10,RNF170,PRRT4" MicroRNA hsa-miR-4329:mirSVR_highEffct hsa-miR-4329:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.93E-47 2.21E-43 1.20E-46 1.11E-45 131 590 "ARID1A,CC2D2A,LRRC7,SMIM17,BIN1,VAT1L,TNRC6C,ARNTL,ZBTB10,NUMB,B3GALT2,SGCE,CACNA1G,CDH8,RCBTB2,CHGB,COL4A5,CDC42BPB,GDA,ARHGEF10,DOCK4,MAML1,DGKB,DGKG,BRINP1,DBI,DNAJC6,ALKBH8,DOCK2,DPYSL2,FCF1,SUGP2,GOLGA7,STARD3NL,RCAN2,ENPP6,PIPOX,RCSD1,EXTL2,FABP7,FGF11,FGFR1,TMEM164,ATP13A4,NELFCD,ZNF605,CGREF1,PHYHIPL,NEURL4,ZMAT1,DKK3,GALNT15,B4GALNT1,SIGLEC8,ZNF559,DISC1,TUBGCP4,ADAM28,GHR,CBX1,MAP7D2,GPR22,IDH3B,FGFBP3,ARHGAP12,CLEC18A,MARK3,MBD1,MBNL1,MBP,MOG,ADAM22,DDX25,CTNNA3,NDP,NTRK3,CHAMP1,BEST3,PDZRN4,PMP2,CDIP1,LRP12,ING3,DRAM2,PPP1R1A,WBP1L,SIDT1,UHRF1BP1,SH3TC2,FAT4,RFX3,RFX5,ZDHHC4,CCDC102B,ASIC4,SEC14L1,ITSN1,MAGI3,AMBRA1,CHD9,FHOD3,PPP4R3A,MBD5,UNC80,BDP1,KDM4C,IDI2-AS1,EPB41L3,GSE1,DMXL2,PCDHB7,FRYL,ITGB3BP,AP4E1,BEX4,KCTD2,SMUG1,SSBP2,TUBB2A,CADM1,USP1,RICTOR,TRIM9,NDRG4,LRP8,MPPE1,NELFE,UBE3B,HNRNPA3,KLHDC1,SOCS4" MicroRNA hsa-miR-199a-5p:PITA hsa-miR-199a-5p:PITA_TOP PITA 3.98E-47 2.24E-43 1.22E-46 1.12E-45 87 259 "RALGAPA1,CCDC85A,ADD3,USP31,SEMA6A,ARHGAP20,ANK3,MAP4K3,ALS2,DDX3Y,SYNJ1,FUBP1,CDH2,LARGE1,CLTC,SEC24C,MYEF2,MAGI2,KLHL3,SACS,DYRK1A,ABCC5,TSPAN5,YAF2,PAN3,SRRM1,ERBB4,FCGRT,KIAA1109,PRKAG2,DCTN2,MEGF10,SRRM4,GCNT2,CSDC2,PPARGC1A,RND1,TOX3,MAP7D2,GPD1,FAM19A2,KLF12,BACH2,HLF,ARHGAP12,ZFYVE27,MAP2,MEIS2,MGAT3,PPM1L,AFDN,MN1,GIT1,PDE4D,PIK3CD,TMEM255A,SH3TC2,FIGN,RORB,CLIP1,ATXN7,SCN3A,ZFP2,PPP1R9A,NTNG1,ST6GAL1,BTBD3,SORCS3,SOX11,SP2,KIF1B,EPB41L3,LARP4,GANAB,CAMSAP2,ANO4,ARHGEF12,SIRT1,SLC44A1,CADM1,XRCC4,RGMA,STOX2,WNK3,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-199b-5p:PITA hsa-miR-199b-5p:PITA_TOP PITA 3.98E-47 2.24E-43 1.22E-46 1.12E-45 87 259 "RALGAPA1,CCDC85A,ADD3,USP31,SEMA6A,ARHGAP20,ANK3,MAP4K3,ALS2,DDX3Y,SYNJ1,FUBP1,CDH2,LARGE1,CLTC,SEC24C,MYEF2,MAGI2,KLHL3,SACS,DYRK1A,ABCC5,TSPAN5,YAF2,PAN3,SRRM1,ERBB4,FCGRT,KIAA1109,PRKAG2,DCTN2,MEGF10,SRRM4,GCNT2,CSDC2,PPARGC1A,RND1,TOX3,MAP7D2,GPD1,FAM19A2,KLF12,BACH2,HLF,ARHGAP12,ZFYVE27,MAP2,MEIS2,MGAT3,PPM1L,AFDN,MN1,GIT1,PDE4D,PIK3CD,TMEM255A,SH3TC2,FIGN,RORB,CLIP1,ATXN7,SCN3A,ZFP2,PPP1R9A,NTNG1,ST6GAL1,BTBD3,SORCS3,SOX11,SP2,KIF1B,EPB41L3,LARP4,GANAB,CAMSAP2,ANO4,ARHGEF12,SIRT1,SLC44A1,CADM1,XRCC4,RGMA,STOX2,WNK3,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-149-3p:Functional MTI Functional MTI miRTarbase 4.29E-47 2.41E-43 1.31E-46 1.20E-45 158 834 "XKR4,ADAR,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,HAP1,CAMK2A,ISPD,CBS,SLC16A4,MYOM2,LONRF2,CDR1,DLGAP3,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,PHYHIP,TOMM20,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,ABI2,RASA4,PLEKHA1,MRNIP,ANKRD13B,IGSF6,WAC,FGFR1,TRMO,PNMA2,KBTBD12,TRAF3IP2,HBS1L,NKX6-2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,SCRG1,AGBL5,ZNF491,SOWAHA,IGF1,DOCK7,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,CCDC80,MSI1,JAKMIP3,NBL1,NDUFA5,NEUROD2,NFIX,NOVA2,SLC11A2,NRGN,TBC1D25,OGDH,OGG1,ZNF713,PDGFRA,GPR173,BEST3,PFKFB3,CDK14,CCSER2,RETREG2,FAT3,PPP2R2B,PTPA,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,RAB5B,CEP97,PLEKHB2,SH3TC2,IQSEC3,PRRT2,MORC4,MYH14,PGBD4,EMID1,HES6,MYO18A,CLSTN1,SLC1A2,PEX26,SMTN,PKNOX2,ZKSCAN3,ZCCHC24,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,HHIP,ARL10,THRA,ERCC6L2,KCTD2,TMPRSS5,SSBP2,RFTN2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,NAV2,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-92a-1*:mirSVR_highEffct hsa-miR-92a-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.29E-47 2.41E-43 1.31E-46 1.20E-45 119 491 "SYN3,FAM135A,AMT,USP28,PPFIA4,PHF12,SEMA4G,DACT3,RGS9,NRP2,CACNA1B,CBLN1,CBR1,MAGI1,UBE2L6,TPP1,IQCK,PCYT1B,AKAP6,GDA,CLIP3,RGS6,SEC24C,DDX46,ALKBH8,USP3,ATN1,DTNA,ECM2,EDN1,EMX2,EPB41,EPHB1,SIRPB1,FCGR3A,IP6K2,RASL10A,B4GALNT1,JPH4,KIAA1841,DNER,TCERG1,LUZP2,DCLK2,GRIA4,NR3C1,GRM7,SOX21,MAEL,HNRNPK,SOWAHA,NKD1,KCNJ11,KCNK2,KCNMA1,HECTD2,MBNL1,LRP1B,MEIS1,MEIS2,KITLG,FXYD6,NFE2L2,NNAT,SMIM11A,PDPK1,ZDHHC8,PLIN1,ANKRD16,PILRA,DRAM2,PRKAB2,TMEM260,EML5,NWD1,HKR1,ZDHHC14,RFX4,FBXW7,ATAT1,TRIM46,ZFP30,ARX,MYO18A,FAM81A,FAM214B,PKNOX2,SPHKAP,NAXD,SMARCE1,RIMS1,PALLD,HECW1,DDN,CLSTN2,SAMSN1,LRRC4,INKA2,SEPT8,TACR1,ADGRL3,FBXW11,ZFP90,FRYL,THBS4,ZNF346,TRPS1,SLC35A4,BEST1,WIPF1,TMEM178A,CIAPIN1,RGS7BP,KAT6A,TMEM63C,FBXO36,CERS6,NETO1,SLC4A10" MicroRNA hsa-miR-129-5p:Functional MTI Functional MTI miRTarbase 4.40E-47 2.47E-43 1.34E-46 1.24E-45 135 625 "AS3MT,GALNT13,ADD3,TEX22,MTA3,PCDH19,KCTD16,TAOK1,SEMA6A,CEP126,USP28,APC,ARSE,MARCH3,NCOA1,SLC2A11,NOL4,BCL7A,BID,CACNG1,CALM1,ISPD,CBS,TBRG4,COL9A2,LETMD1,AKAP5,RTTN,CLOCK,HAPLN1,RNF14,ANKRD44,ABCG1,VCAN,USP6NL,KIAA0408,JAKMIP2,TIAM2,ZC3H11A,DNAH9,ABCC5,EBF1,ST8SIA3,KLHL5,PLEKHO1,EPB41L1,EPS8,ACSL4,TAOK3,UFM1,TMEM151A,BRSK1,GABRB1,FAM184B,HBS1L,ATP8A2,SRCAP,NTNG2,GLUL,POLL,GNAL,PRRC2B,CNDP1,GRM3,RNF165,LINC01551,FAM107A,SLC2A6,HMGB1,HNF4G,ZDHHC15,IGF1,SCIN,IBA57,KCNJ3,CYP27C1,L1CAM,LIMS1,GPR155,MBD1,SESN3,NEUROD2,NPTX1,PDE3A,PDGFRA,PDPK1,ABCB1,ZNF655,SMIM7,STRN3,PPARA,CEP41,CNTLN,MTMR10,NKAIN1,ZNF793,NWD1,ZYG11B,RET,FIGN,GSTCD,ELP2,KCNIP3,SATB1,SCN2B,SLC30A10,SOX6,SH3BP2,NTNG1,MAGI3,FNDC3A,EPN2,LRRC55,EPC1,IGSF9B,RBM26,FGD4,CAMTA1,UNC5D,KIAA0930,SLC44A1,FAM124A,PARD3,KAT6B,ZNF384,RUNDC3B,TRPS1,VLDLR,ZNF708,ZNF154,REEP1,LMAN2L,WIPF2,PAK5,HNRNPA3" MicroRNA hsa-miR-6883-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.62E-47 2.59E-43 1.40E-46 1.29E-45 157 825 "XKR4,ADAR,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,HAP1,CAMK2A,ISPD,CBS,SLC16A4,MYOM2,LONRF2,CDR1,DLGAP3,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,PHYHIP,TOMM20,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,ABI2,RASA4,PLEKHA1,MRNIP,ANKRD13B,IGSF6,WAC,TRMO,PNMA2,KBTBD12,TRAF3IP2,HBS1L,NKX6-2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,SCRG1,AGBL5,ZNF491,SOWAHA,IGF1,DOCK7,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,CCDC80,MSI1,JAKMIP3,NBL1,NDUFA5,NEUROD2,NFIX,NOVA2,SLC11A2,NRGN,TBC1D25,OGDH,OGG1,ZNF713,PDGFRA,GPR173,BEST3,PFKFB3,CDK14,CCSER2,RETREG2,FAT3,PPP2R2B,PTPA,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,RAB5B,CEP97,PLEKHB2,SH3TC2,IQSEC3,PRRT2,MORC4,MYH14,PGBD4,EMID1,HES6,MYO18A,CLSTN1,SLC1A2,PEX26,SMTN,PKNOX2,ZKSCAN3,ZCCHC24,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,HHIP,ARL10,THRA,ERCC6L2,KCTD2,TMPRSS5,SSBP2,RFTN2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,NAV2,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-6785-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.62E-47 2.59E-43 1.40E-46 1.29E-45 157 825 "XKR4,ADAR,ELFN2,RNF157,PLEKHH1,HACE1,TXNDC16,AK2,TRMT9B,PHF12,PPFIA3,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,HAP1,CAMK2A,ISPD,CBS,SLC16A4,MYOM2,LONRF2,CDR1,DLGAP3,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,SLITRK5,UBXN2A,USP6NL,MYADM,GAPVD1,PHYHIP,TOMM20,IP6K1,DNAL1,SPATA2,CHRDL1,DNAH9,SLC29A4,PHC2,TMTC1,ABI2,RASA4,PLEKHA1,MRNIP,ANKRD13B,IGSF6,WAC,TRMO,PNMA2,KBTBD12,TRAF3IP2,HBS1L,NKX6-2,DISC1,AHDC1,CRCP,GLUL,STARD3,GNG4,TPPP,BVES,IRAK3,SCRG1,AGBL5,ZNF491,SOWAHA,IGF1,DOCK7,IBA57,KCNK3,SMAD9,MAT2A,MATN3,PPM1L,CCDC80,MSI1,JAKMIP3,NBL1,NDUFA5,NEUROD2,NFIX,NOVA2,SLC11A2,NRGN,TBC1D25,OGDH,OGG1,ZNF713,PDGFRA,GPR173,BEST3,PFKFB3,CDK14,CCSER2,RETREG2,FAT3,PPP2R2B,PTPA,KANSL1,BDNF-AS,MTMR10,PTPRE,QDPR,RAB5B,CEP97,PLEKHB2,SH3TC2,IQSEC3,PRRT2,MORC4,MYH14,PGBD4,EMID1,HES6,MYO18A,CLSTN1,SLC1A2,PEX26,SMTN,PKNOX2,ZKSCAN3,ZCCHC24,MCF2L2,SSTR1,STX1A,FAM208A,TPCN2,USP22,SLC19A3,HHIP,ARL10,THRA,ERCC6L2,KCTD2,TMPRSS5,SSBP2,RFTN2,RPL7L1,MGAT5B,KLC2,RICTOR,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,NAV2,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-3197:mirSVR_lowEffct hsa-miR-3197:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-47 2.75E-43 1.49E-46 1.37E-45 137 643 "ABCF1,SYS1,ADARB2,GALNT16,ADORA2A,HACE1,WDR35,LTBP4,MRTFA,CNIH2,CDK10,CASK,SPTBN4,MARK4,CAPRIN2,BRINP2,ADAM15,RGS9,BMP7,SYNJ1,CABP7,HAP1,LGI1,PPT2,NGEF,ARHGEF6,IQCK,LETMD1,NCOR2,ARHGEF10,PLCH2,CFAP61,TOX,PHF19,DLG2,DLX1,SHANK1,DPH1,ACOT8,DMTN,SIRPB1,ECSIT,EVL,RASL10A,ATP6V1H,GABRA2,B4GALNT1,DISC1,ATP8A2,LRRC37A6P,CPLX1,GFAP,GFER,KIRREL3,TTBK1,STARD3,GPT2,PSRC1,GPER1,GRM2,LINC00839,ZBTB49,RABL2A,SHISA6,CELF5,GAREM2,KNDC1,KCNN1,L1CAM,MBP,LDLRAD3,MYO7A,CCDC13,NUMA1,ZNF827,PCSK5,PDE4A,PFKFB2,ZFYVE21,CDIP1,NKAIN4,PPP5C,WBP1L,PEX5,TUG1,RASGRF2,PRRT2,RFX2,ARHGEF10L,SEC61A2,RIC8B,CCDC25,RPS6KA2,EMID1,FAM192A,TNFRSF19,SH3BGR,ITSN1,FUZ,NTNG1,SHMT2,SLC6A1,LRRC55,SLC6A8,SLC11A1,SMARCA4,SMARCC2,USP33,MYCBP2,KDM4C,SSPO,MAPK8IP3,SEPT3,SYP,SIN3B,CLASP1,TMEM151B,TNS2,AP4E1,FBXL16,TMEM9,TMPO,DAAM2,STXBP4,KCNE5,UBTF,TOM1L2,KLC2,GUSBP1,LGI4,ZNF138,REEP1,GDPD5,PARP11,PDSS2,UBE3B,LAS1L" MicroRNA "TATTATA,MIR-374:MSigDB" "TATTATA,MIR-374:MSigDB" MSigDB 4.94E-47 2.78E-43 1.50E-46 1.38E-45 88 266 "ABAT,ABR,ACTN1,CSMD2,SLITRK1,PCDH10,FAM135A,MAP4K3,ARHGAP5,ASCL1,NCOA1,NUMB,TMEM108,ATP1A1,LDLRAD4,NOG,NUMBL,QKI,HECTD1,NIPBL,HAPLN1,PLPPR4,NTM,WDR20,DMD,MBNL2,EIF4G2,SEZ6,DENND4A,EYA1,ABCA8,MED12L,UBE2E3,MEX3B,FOXG1,GBX2,PPARGC1A,TCERG1,TNRC6A,GPM6A,STMN2,NR3C1,HLF,BRINP3,MAP2,LRP1B,MEIS1,AFF1,NFIX,NKX2-2,NOVA1,NPTX2,OCRL,PDE4B,PDE4D,PDPK1,ANLN,PPP2R2C,PKIA,RALGDS,BSDC1,RFX4,RORB,ATXN1,SCN2B,SYBU,NLGN1,ARHGEF40,CPEB4,ZCCHC24,SP4,ZNF423,IQSEC2,C11orf87,SRPK2,SYT1,CAMSAP2,ATMIN,TCF12,SYNE1,UBE2H,SF1,SMARCAD1,PMEPA1,GOPC,PAK5,SOCS4,ST8SIA2" MicroRNA "TAATAAT,MIR-126:MSigDB" "TAATAAT,MIR-126:MSigDB" MSigDB 5.15E-47 2.89E-43 1.56E-46 1.44E-45 78 205 "ARID1A,HECW2,TAOK1,ADGRF5,ALCAM,OGT,LRCH2,MARCH3,ATP2B1,ZNF583,ADGRB3,BCL2L2,DDR1,SPAG9,RUNX1T1,NFS1,FOXN3,AHCTF1,CHD1L,LRRC3B,HDAC4,MYEF2,USP3,ATN1,SRRM1,EYA1,ZIC4,AFF2,GABRA5,SRRM4,GHR,PPARGC1A,DCLK2,GRIA2,GRIK1,GRM8,KLF12,HMGB1,NKD1,KCND2,KCNH2,MATN3,MIA2,MID1,MMP16,MYT1,ZC3H12B,NOVA1,NTRK2,PCSK2,ING3,PPP2R5E,PLEKHB2,RFX4,ZFHX4,ZNF354C,SEMA6D,FNDC3A,UHRF1BP1L,CDK19,ERBIN,TCF12,CLASP1,ARHGEF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TRPS1,FLRT2,TBC1D15,ZIC1,PRDM8,SLC4A10" MicroRNA hsa-miR-3064-5p:TargetScan hsa-miR-3064-5p TargetScan 7.21E-47 4.05E-43 2.19E-46 2.02E-45 109 415 "RBM10,NDRG3,ADCYAP1R1,GRAMD1B,LCNL1,GOLGA7B,OGT,C6orf89,ALS2,AMER3,KIAA1614,CAPRIN2,CADM3,KIF1A,BCL2L2,FUBP1,MMD2,DIRAS1,CAMK2G,CCNT1,REPS2,IGFN1,HECTD1,BAG4,CLOCK,C2CD2,CRY2,CSF1,CNTNAP2,CMTM5,FRMPD4,DGKG,IP6K1,JAKMIP2,KLHL3,FAM107B,RPS6KL1,DPYSL2,FARSB,CELSR3,EIF5,ELAVL3,PLEKHO1,EPB41L1,RABEPK,AGAP2,PSD2,CELF1,DKK3,GABBR1,BRPF3,B4GALNT1,MTHFD2,INPP5K,CPLX2,GFRA2,GRIK3,PTPRT,GUCY1A2,RASSF8,NXPH3,KIAA1755,IL6R,KCNB1,KCND3,KCNN3,KIF2A,KIF5C,GIT1,CCDC80,C10orf105,SAMD14,NFIX,NFYA,NNAT,NOVA2,PCSK5,PDE2A,PDE1B,KCTD15,PLEC,CDIP1,CNNM2,MDGA2,RNF220,CYB561D1,RORB,PRR5L,DZIP1,ABLIM3,EPC1,FAIM2,CLSTN2,PHLDB1,FAM168A,CNTN2,RPGRIP1L,NACC2,CBX5,FAM124A,ELP5,CADM1,BCL2L13,PCDH20,INTS3,DNALI1,RGMA,LMAN2L,MSRB3" MicroRNA "GTACTGT,MIR-101:MSigDB" "GTACTGT,MIR-101:MSigDB" MSigDB 7.81E-47 4.39E-43 2.37E-46 2.18E-45 84 242 "ASIC1,ARID1A,ADCY6,SPOP,UNC79,OGT,PPFIA4,PPFIA1,APP,TMEFF1,DDX3Y,KIF1A,CDK5R1,MTMR2,CACNB2,USP6,CBFA2T2,C1orf52,MAGI1,CLCN3,QKI,MYRIP,SOCS5,LONRF1,MAGI2,G3BP2,CPEB2,DYRK1A,ABCC5,PHF20L1,EPB41L1,EYA1,KHDRBS3,DOT1L,STAG2,KAT7,FAM222A,HAS2,NEGR1,ZNF385B,PACRG,MARK1,MBNL1,MYCN,NACA,NEUROD1,NOVA1,PCDH8,PDE4A,PDE4D,GPR85,PLXNB1,PURG,ING3,LRRN3,USP47,REV3L,UBR7,NUDT11,ZFHX4,ZNF532,ROBO2,FBXW7,ATXN1,CPEB3,ABLIM3,BTBD3,SOX11,SRPK2,POGZ,LRRC4,ERBIN,GSE1,CAMTA1,TAL1,FBXW11,PUM2,RASD2,FLRT2,ZNF24,EMSY,MPPE1,ADAMTSL3,ADAMTS10" MicroRNA hsa-miR-4322:mirSVR_highEffct hsa-miR-4322:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.44E-47 4.74E-43 2.56E-46 2.36E-45 116 470 "CLK4,CSMD3,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,ALS2,VAT1L,AQP6,DYNLL1,ATP2B1,LDHD,CACNA1D,CACNB2,RUNX1T1,CLDN10,AIFM1,L3MBTL4,COPB2,RAB33A,COG1,CNR1,NCOR1,SNCAIP,CSF1R,PDE4DIP,ST18,DOCK4,HDAC4,BRINP1,PLEKHM1,CEP170,FBXO25,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,CAP2,PSD2,SLC37A3,ARFGAP2,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,GRIA1,HPS5,PADI2,ZNF546,KCNC2,GPR62,KCNJ4,KCNJ16,KCNN3,PAXBP1,MAOB,MDM4,MEIS2,LAYN,NME4,PDE3A,CAMKV,CRLS1,SAMD9,WBP1L,CNTLN,FAM120C,RAD52,VEPH1,RGS3,RGS4,CSRNP3,SLC1A7,SLC8A3,ATF7IP,TET1,WDTC1,ZSWIM8,ENKUR,KDM4C,LMO3,TAB2,VPS13A,ARC,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,RGS7BP,FAM13C,RNF146,SPATA13" MicroRNA hsa-miR-515-3p:mirSVR_highEffct hsa-miR-515-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.13E-46 6.32E-43 3.41E-46 3.14E-45 140 674 "NCKAP5,ADCY6,ADD1,ZNF608,KIAA1324,SMIM17,ARHGAP20,OGT,ANK3,PPFIA1,ASPH,ATP1A2,ADAM23,SGCE,CA4,CACNA1D,LRRFIP1,RCBTB2,SRSF11,CHGA,JAM2,COG1,IQCK,ARMC8,AKAP6,CPS1,CLOCK,CS,PDE4DIP,CST3,CFAP61,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,BLOC1S6,SNAP91,DLG2,NR1D2,ABI1,PDCD6IP,DNM1L,PHF20L1,MRNIP,DCTN4,EPB41,EPB41L2,ENPP6,DNAJC27,WAC,FGFR1,SUCO,HPCAL4,JKAMP,SORBS1,TMEM107,UFM1,NRG3,GABRA3,IQGAP2,SYT17,KIAA1841,GATM,GGT7,RND1,RAB30,GLS,NR3C1,LINC01551,SOX21,PSIP1,HSP90AA1,HTR5A,ZNF678,KCNC2,KCNJ3,LMO2,MAT2A,MBD1,ZNF680,MRPL42,ZNF92,MYO6,NCAM1,SFR1,NF1,NOVA1,HCN1,NUMA1,TBC1D25,CDK18,PRTG,MTRF1L,RETREG2,BDNF-AS,PXK,PTPRB,PTPRG,FAT4,RASGRF2,SLC6A15,PNMA8A,CYB561D1,CCDC102B,CSRNP3,HSPA4L,CPEB3,NTNG1,DZIP1,ANKRD6,NUBPL,BTBD3,DHX30,RCOR3,CMTR2,KIF1B,ITPRID2,SSTR1,SYT1,ANKRD28,CAMTA1,MCF2L,TCF12,SYNE1,DOCK9,PUM2,SIK3,HHIP,KAT6B,NPL,ANKRD20A2,WIPF1,SMARCAD1,DHX33,DNALI1,LINC02210,UBE3B,DPF3" MicroRNA hsa-miR-1301:PITA hsa-miR-1301:PITA_TOP PITA 1.16E-46 6.50E-43 3.50E-46 3.23E-45 87 262 "ARID1A,NDRG3,USP31,BEND6,DPP10,MAP4K3,CDK13,DDX3Y,ATP2B1,ATP2B3,NOL4,SRSF11,CHN1,NCAN,PHACTR3,PHF19,MAGI2,SMG7,G3BP2,CHRDL1,DLG2,DLG3,HIPK3,TENM1,ENO2,WAC,ATP8A1,TOMM40L,TESK2,OLFM1,SUCO,B3GAT1,MEGF11,GABRB3,PPARGC1A,GPD2,CECR2,CIT,KLF12,BACH2,KLC1,MBNL1,MSI1,MDGA1,NBL1,ZC3H12B,NFIX,NPTX1,HCN1,ZNF827,PDE4D,OLA1,PIK3R1,ROBO2,RASA3,MYO18A,FBXO11,RCOR3,RIMS1,ZCCHC24,HECW1,ERC1,PEG10,CLASP2,ELOVL4,SULF2,C3orf70,CAMTA1,TCF4,SATB2,SZT2,ARHGEF12,TNS2,FRYL,SIRT1,TMOD1,RIMBP2,CSMD1,NR2C2,ZBTB14,TRIM9,POLR3H,PMEPA1,EMSY,SLC17A7,SNX27,HNRNPA3" MicroRNA hsa-let-7d*:mirSVR_lowEffct hsa-let-7d*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-46 1.03E-42 5.56E-46 5.12E-45 106 396 "CPNE2,SLITRK1,ZNF608,CCDC146,TMEFF1,NOL4,DPY19L3,DOCK11,BCL2L2,NAE1,CAMK2D,CANX,CDC42,SRSF11,RAB33A,HECTD1,LETMD1,AKAP5,ATRNL1,PLXNA4,APPL1,PLCXD3,GAPVD1,ZFYVE16,MATR3,YTHDC1,ZEB2,SRGAP3,HS3ST2,ARRDC4,DTNA,E2F5,EGFR,PLEKHA1,EYA1,ARMCX1,SH3YL1,FLT1,TRMO,TACC2,GABRA5,GRIA2,NR3C1,ELOVL5,ACOT7,TCEAL6,DOCK7,RIPPLY2,LIFR,MAP6,SYT9,MDM4,MYO9A,NEUROD1,NF1,NOVA1,LRIT2,NRCAM,OPHN1,PCDH8,PDE2A,PDE3B,CCSER2,XRN1,PCDH18,GDPD1,MASP1,SYTL2,FAT4,RAP1GDS1,OXR1,MSANTD2,REV3L,ZNF532,ZC3H14,PRR5L,SATB1,SH3GL3,KIF16B,DOCK10,SHC4,FNDC3A,ELMO2,SLC22A4,RCOR3,INAVA,FAM219A,PDZD2,TAB2,SSTR2,MAPK8IP3,ZSCAN29,RGL1,SULF2,ATMIN,WASHC4,ZFPM2,TGFBR3,HHIP,TLR4,AMOT,MEAF6,ZIC1,SNX27,TMEM163,FAM47E" MicroRNA hsa-miR-612:PITA hsa-miR-612:PITA_TOP PITA 1.92E-46 1.08E-42 5.81E-46 5.36E-45 79 214 "SDE2,CSMD2,FZD9,NLGN4X,HECW2,APBB2,USP37,BTRC,FOXN3,COL4A5,CSNK1G3,RIMS4,ERC2,ZC3H11A,DLG2,DPYSL2,CNNM1,EGR3,TENM1,DMTN,SRRM1,ATP8A1,AGAP2,GABRA5,CHL1,GABRB3,JPH4,CPLX2,RUNDC3A,TTBK1,PCDH11X,KDM2B,LPAR4,TOX2,KLF12,BACH2,MIER3,IBA57,LRRTM3,KCNB1,KCNK2,MEF2C,MPP2,RSPO2,MDGA1,MYBPC1,PDE4D,GDAP1L1,PIK3R1,ANKRD16,NXPH1,PPP2R2B,PPP3CB,RASGEF1B,FAM120C,MARCH1,ARID4A,RGS4,CASC3,ITSN1,CHD9,WDR37,RIMS1,SNCA,SP2,LHFPL4,SS18,STX1A,WWC1,SATB2,TCF12,PSD3,ITGB3BP,THRA,RBFOX2,SMARCAD1,EMSY,WIPF2,FRMD6" MicroRNA hsa-miR-515-5p:PITA hsa-miR-515-5p:PITA_TOP PITA 2.00E-46 1.12E-42 6.05E-46 5.57E-45 95 317 "GPR158,DGKD,FAM131A,API5,USP37,SHTN1,TMEM263,ZFYVE28,ASCL1,CHRD,NCOA1,DDX3Y,SLC4A4,ATP1B3,DPY19L3,BCL2L2,NRP2,CDK5R1,BSN,CACNA1A,CACNB4,CALM1,QKI,MAP4K4,SLC4A7,ZNF385A,CREB5,PUM1,FRMPD4,TM9SF4,MATR3,HP1BP3,CEP170,ALKBH8,POM121,SNAP91,G3BP2,DLG2,DMD,CPEB2,EFNA3,RBM12,GPR61,ABI2,ELAVL2,PAN3,EMX2,RASGRP2,ETV1,CLVS1,TAOK3,TMEM164,SYNCRIP,TMEM107,MEGF11,CAB39,MSTN,GRIA4,GRM1,ADAMTS6,MAEL,HNF4G,INSM1,KCNA4,KCND2,KIF2A,MSI1,MXI1,PDGFRA,MED1,MINDY2,PTPRD,PTPRE,PEX2,RIPOR1,SLC25A36,SETD5,SCN8A,CASC3,SLITRK3,ST3GAL3,EPN2,PKNOX2,SMARCE1,RIMS1,SNAP25,SP4,NMNAT2,PLCB1,TCF12,TIAM1,RGMB,UBE2H,POLR3H,RGS7BP" MicroRNA hsa-miR-1277:mirSVR_lowEffct hsa-miR-1277:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.06E-46 1.16E-42 6.24E-46 5.74E-45 114 458 "DGCR6,ARID1A,AXIN2,SORCS1,SLC24A4,LGR5,ARHGAP5,ATP2A2,CASTOR3,CACNA1G,ZBED1,SRSF11,TAOK2,NRXN3,SULT4A1,NIPBL,AKAP6,LETMD1,MYRIP,ZFP28,C2CD2,CNTNAP2,KIAA0040,DAPK1,ZEB2,ZBTB24,HEPH,COPS7A,CHRDL1,EXOG,DRP2,MAMLD1,EIF4G2,ANKRD13B,RTN3,FAM198B,TBC1D16,POLK,MEX3B,PCYOX1,GABRA3,NCKAP1,ATP8A2,MMADHC,TOX3,NUDT21,GRB10,GRM1,KIF3A,PTPN5,LINC01102,LRRCC1,INSM1,IPO5,STMN1,ARHGAP12,PTOV1,MYO5A,P2RY13,NASP,OLA1,CDK14,ZDHHC8,ANLN,ZNF655,SLC25A23,PCDH18,MTRF1L,PDZRN4,POU3F2,CRLS1,PPP3CB,CNTLN,PTAFR,PTPRB,ATG16L1,FAT4,ARID4A,SLC25A36,RIC8B,MYH14,RPL15,LGR4,SOX6,GALNT10,SFPQ,SUPT20H,SLC8A3,MAST1,VPS13A,C3orf70,EHBP1,RPGRIP1L,CRB1,GPR161,DAAM2,TP53BP2,RGMB,VLDLR,WIPF1,P2RY12,ZNF17,ZNF24,FSTL5,EML6,ZFAND5,SMARCAD1,SYNC,PRDM8,ADAMTS9,FAM47E,HNRNPA3,PHTF2,FRMD6" MicroRNA "CAGTGTT,MIR-200A:MSigDB" "CAGTGTT,MIR-200A:MSigDB" MSigDB 2.95E-46 1.66E-42 8.90E-46 8.20E-45 91 291 "SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,ATP2A2,NRP2,JAZF1,GPC2,KALRN,SPAG9,SEPT7,EVI5L,FOXN3,PPT2,NRXN1,QKI,CNR1,MYRIP,CDC42BPB,CSNK1G3,CTNND2,KIAA0408,HDAC4,TM9SF4,SNAP91,GRIN3A,ATL1,YAF2,ELAVL2,DLC1,OLFM1,ANKFY1,PHYHIPL,TCERG1,GPM6B,KIF3A,HLF,ACOT7,STXBP5,TTYH2,MBNL1,MMP16,MDGA1,PCDH8,PCDH9,EPN1,TRHDE,PRKACB,PTPRG,PEX5,KHDRBS2,ATAT1,ATXN1,ATXN7,SCN2B,ELMOD1,SFPQ,ITSN1,PPM1E,CHD9,ST3GAL3,SLC6A9,MBD5,SON,MYT1L,SOX5,ZCCHC24,SOX11,SP4,NMNAT2,NFASC,CLASP2,TTBK2,STXBP1,SYT4,CAMSAP2,TCF12,SIRT1,LRRC8A,NR2C2,TSC1,UBE3A,PITPNB,NSD2,XKR7,SNX27,SLC17A6,FRMD6" MicroRNA "CAGTGTT,MIR-141:MSigDB" "CAGTGTT,MIR-141:MSigDB" MSigDB 2.95E-46 1.66E-42 8.90E-46 8.20E-45 91 291 "SEMA6A,AMPD2,OGT,APBB2,TMEFF1,ARNTL,CDK13,ATP2A2,NRP2,JAZF1,GPC2,KALRN,SPAG9,SEPT7,EVI5L,FOXN3,PPT2,NRXN1,QKI,CNR1,MYRIP,CDC42BPB,CSNK1G3,CTNND2,KIAA0408,HDAC4,TM9SF4,SNAP91,GRIN3A,ATL1,YAF2,ELAVL2,DLC1,OLFM1,ANKFY1,PHYHIPL,TCERG1,GPM6B,KIF3A,HLF,ACOT7,STXBP5,TTYH2,MBNL1,MMP16,MDGA1,PCDH8,PCDH9,EPN1,TRHDE,PRKACB,PTPRG,PEX5,KHDRBS2,ATAT1,ATXN1,ATXN7,SCN2B,ELMOD1,SFPQ,ITSN1,PPM1E,CHD9,ST3GAL3,SLC6A9,MBD5,SON,MYT1L,SOX5,ZCCHC24,SOX11,SP4,NMNAT2,NFASC,CLASP2,TTBK2,STXBP1,SYT4,CAMSAP2,TCF12,SIRT1,LRRC8A,NR2C2,TSC1,UBE3A,PITPNB,NSD2,XKR7,SNX27,SLC17A6,FRMD6" MicroRNA hsa-miR-139-5p:PITA hsa-miR-139-5p:PITA_TOP PITA 3.68E-46 2.07E-42 1.11E-45 1.02E-44 95 319 "NDRG2,SLC12A5,TAOK1,LRRC7,ANK1,LRCH2,ZBTB10,ATP2B2,SCAPER,MTMR2,CACNA2D2,ADGRG1,SOCS5,USP6NL,KIAA0408,TOX,ZEB2,MAGI2,SPOCK3,SV2A,DMD,DPP6,ST8SIA3,TSPAN5,MBNL2,EIF4G2,ELAVL2,EMX2,OLFM1,MEX3B,FOXO3,GATM,PPARGC1A,TNRC6A,PCDH11X,LPAR4,GPR37,GRM1,KIF3A,ELOVL5,KCNA1,MAP2,MARK1,MAT2A,MBD1,MBNL1,MEIS2,NAP1L1,NAP1L3,NPTX1,NRCAM,HCN1,PDE3A,PDE4D,PMP22,LRP12,SCHIP1,FAT3,NXPH1,PPP3CB,PBRM1,ZNF532,ATXN1,LRFN5,SCN3A,SCN4B,BTBD3,WDR47,TMEM132D,CPEB4,SMARCA4,TMCC1,SOX1,SOX5,CDK19,ERBIN,SEPT3,NECAB1,UNC5D,TCF4,TCF12,WASHC4,PSD3,FRYL,FBXL16,RBFOX2,CLDND1,ZIC1,TRIM9,NDRG4,ZBTB38,FZD3,RTN4,PAK5,KAT6A" MicroRNA hsa-miR-1263:mirSVR_highEffct hsa-miR-1263:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.72E-46 2.09E-42 1.12E-45 1.03E-44 102 369 "KLHL32,CCDC85A,KCTD16,MAP4K3,API5,ARNTL,CADPS,ZSCAN18,NCOA1,INSYN2B,STX16,SYNJ1,MTMR2,AP1M1,METTL6,CDH8,TIGD7,CHN2,NDST3,CLU,TMEM155,ACBD5,TOGARAM2,ANKRD44,DOCK4,GPRASP1,ZFYVE16,MFAP3L,LYPD1,SNAP91,RAB39B,EFNA3,ELAVL4,EIF1,DUSP27,ANKMY1,FAM198B,GORAB,FER,SPSB4,FGFR1,RGPD5,PHYHIPL,STAG2,GABRA5,MTHFD2,PPARGC1A,GLI2,GLRB,POLL,GRIA2,ADAMTS13,GRM5,VSIG4,ZDHHC15,LRRTM1,JAK1,KCNK1,MAT2A,SRSF12,NEUROD1,ODF2,A2ML1,PLP1,TRHDE,BCAS3,GDPD2,BDNF-AS,C1orf109,CEP97,LGI2,RORB,ACER3,CLIP1,RYR3,PPM1E,FBXO11,SLC1A3,MBD5,UNC80,C11orf87,ZSCAN29,TTBK2,PHLDB1,ARHGEF9,PLCB1,TMEM136,TCEA1,FRYL,TP53BP2,TPM3,ZMYND8,SGK3,LYPD6,ANKS1B,PRDM10,CAB39L,PDSS2,FAM13C,HNRNPA3,CASC15,IFT88" MicroRNA hsa-miR-1306:mirSVR_lowEffct hsa-miR-1306:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.65E-46 3.74E-42 2.00E-45 1.85E-44 114 463 "SERPINA3,ACADM,ADCY2,DSCAML1,PLEKHH1,OSBPL6,WDR35,TXNDC16,ALK,ALS2,FAM131A,PPFIA3,SEMA4G,MADD,CASK,ARNTL,RGS20,JAZF1,AP1M1,CAST,LDB2,CHRNA4,EPS15L1,CLU,CNN3,AKAP7,COL11A2,NCOR2,FEZ2,CSNK1G3,SRGAP3,SGSM2,TMCC2,DLG3,DLX1,CPEB2,SLC12A6,DRD1,E2F5,AASDH,USH1C,EDN1,SUGP2,TENM1,EPB41L2,EPS8,NRN1,GORAB,BAIAP2,TMEM164,AMOTL2,NOP56,KHDRBS3,FYN,ATP8A2,GK,TNRC6A,ZNF782,GPR37,ADAMTS13,ZBTB49,ARHGAP19,VSIG4,HNRNPK,ZNF385B,KCNK2,KCNN1,KIF5C,STXBP5,KTN1,STMN1,LRP1B,NEUROD1,NFIX,NOVA1,NRCAM,NTRK2,IGSF11,OPCML,SSH1,LRP12,OCIAD1,RALGDS,GTDC1,FBXW7,LGR4,ABCA11P,SATB1,SEC14L1,TRIM46,SUPT20H,NTNG1,LIMCH1,ERC1,FGD4,POPDC3,CNTN2,PCDHB3,ARHGAP9,AHCYL2,CYB561A3,TNFRSF1B,TRIO,AMACR,TRPC3,KCNE5,TTC3,FRRS1L,LINC00689,ZBTB14,SLC38A1,SEMA3B,PPP1R3F,JPH3" MicroRNA hsa-miR-455-3p.2:TargetScan hsa-miR-455-3p.2 TargetScan 7.13E-46 4.01E-42 2.15E-45 1.98E-44 84 248 "ABR,CSMD3,ADCY2,RNF150,ANK3,DYNLL1,EIF4G3,BCL7A,DST,FUBP1,CAMK2B,FMNL3,CFL2,CHGA,CLCN3,NIPBL,ARMC8,COL4A5,NRG2,CREB5,LIN54,G3BP2,CHRDL1,RAB39B,HIPK3,EGFR,ABI2,EIF4G1,RCAN2,ATP8A1,B3GAT1,MPP6,CPLX2,CPLX1,GBX2,CYP46A1,GLYR1,GPR75,GRIA1,GRID1,GUCY1A2,AGFG1,NKD1,DIPK1A,KCNC2,KCND2,KCNJ3,KIF5C,HS6ST3,MYO9A,MYT1,NCAM2,NFIA,NOVA2,NPTX1,OCRL,OPCML,FAM216A,POU3F2,PPP3CB,PRRT2,GTDC1,FIGN,KLHDC8A,ROBO2,RORB,RYR3,SATB1,CSRNP3,ATXN1,DRAXIN,FAM19A1,CPEB3,CCDC88A,MYT1L,NFASC,LMO3,PRRC2C,MMS19,FRYL,RPRM,RBFOX3,MAP3K12,LRP8" MicroRNA hsa-miR-1827:PITA hsa-miR-1827:PITA_TOP PITA 7.76E-46 4.36E-42 2.34E-45 2.15E-44 86 261 "SDE2,ASIC1,XKR4,SLC12A5,LRRC7,SEMA6A,ANK1,ANK3,CAPRIN2,EIF4G3,JAZF1,LDLRAD4,CACNA1E,CALB1,THSD7A,CAMK2A,CAMK2B,CAMK2G,FMNL3,REPS2,NRXN2,FAM19A5,MAP4K4,CNN3,PICK1,LETMD1,MYRIP,CTNND1,ELMSAN1,ABCC5,ST8SIA3,CELSR3,SLC43A2,CORO2B,IQGAP2,GPR162,GPD2,PCLO,CELF3,BACH2,IGF1,ZIC5,IBA57,INSM1,KCND2,KTN1,NCOA7,SYT9,CHIC1,PABPC1L2A,NRGN,ZNF827,PBX1,ANKRD16,SCHIP1,RETREG2,POU3F2,FAM120C,RAB5B,SH3TC2,SETD5,CYB561D1,SCP2,ELMOD1,CPEB3,RCOR3,KIF21B,NMNAT2,NCDN,FAM168A,ASTN2,MTCL1,MCF2L,TCF4,KIAA0930,PSD3,TIE1,HEY1,CBX5,NR2E1,TPM3,DOK6,KCNE5,CCDC136,ZIC1,PIANP" MicroRNA hsa-miR-505:PITA hsa-miR-505:PITA_TOP PITA 7.92E-46 4.45E-42 2.38E-45 2.20E-44 83 242 "ABAT,ACTN2,SNX30,TMEM263,ATP2B1,ARHGEF7,BSN,CACNB4,CANX,USP6,C1orf52,SRSF11,FOXN3,CLTB,QKI,MYRIP,CRY2,ERC2,KIAA0408,DOCK4,SPOCK3,CPEB2,E2F5,EYA1,PRKAG2,CELF1,TBR1,GABRG2,CYP46A1,PPARGC1A,SPIN1,GNAO1,GPM6A,GRB10,ADAMTS6,HMGB1,KCNMA1,KIT,LRP1B,MEIS1,MEIS2,MYCN,NEXMIF,HNRNPM,NDP,NOVA1,NPTX1,CDK14,PMP22,LRP12,SCHIP1,RETREG2,POU3F4,MINDY2,PPP3CB,SNRK,PTK2,USP47,SETD5,SOX6,KIF21A,WDR37,EPN2,SLC8A3,MYT1L,SOX5,SP4,ELOVL4,SEPT3,KLHL7,C3orf70,ADGRL3,TRIM2,PUM2,DAAM2,TRPS1,CADM1,PITPNB,SF1,REEP1,SLC38A1,SCG2,SLC4A10" MicroRNA hsa-miR-219-1-3p:mirSVR_highEffct hsa-miR-219-1-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.29E-46 4.66E-42 2.49E-45 2.30E-44 147 749 "SERPINA3,SLITRK1,CCDC85A,OGT,PARG,STK33,ASPH,ATP2B1,JAZF1,CALM1,CANX,AIFM1,CLCN3,FBXO7,CNTN1,RCHY1,ZNF385A,SLC35F1,RNF14,C1QL2,CS,SEC24C,MICAL2,VCAN,CFAP61,CTNND1,CX3CR1,CYBB,RIPOR2,CENPL,KIAA0586,DGKB,ZBTB24,DDX46,RHOBTB1,WDR20,EDN3,PHF20L1,C8orf37,SEZ6,GORAB,SEC24B,POLK,CAP2,ATP2C1,NSG1,FYN,STAG2,MEGF11,GALR1,ERAP1,WASF3,MYOZ2,TUBGCP4,ZNF638,DCLK2,GRB10,GRIA1,PLCD4,FAM19A2,BVES,MAEL,ZHX1,MIER3,IGF1,IL6R,ITGAM,JAK2,KCNMA1,KCNN3,CREG2,KTN1,LAMP2,MBNL1,IL17D,MEIS2,SRSF12,MEST,XRRA1,ZNF680,NCAM1,NF1,OLR1,OXTR,CNTN3,PDE4D,GNG2,TRHDE,PPM1B,PPP3CC,HYDIN,SAMD9,MDGA2,PIGG,PLPPR1,ZIK1,PTPRB,EML5,PTPRE,ZNF493,ZDHHC14,RIC8B,ZFHX4,ROBO1,YY1AP1,SPIN3,LRRK2,ABCA11P,SEMA6D,SLITRK3,CNKSR2,KBTBD4,ZFP1,PDZRN3,PDZD2,SOX2,KIF21B,HECW1,RBM26,NFASC,ITPRID2,ZNF302,SS18,TTBK2,SYT1,ROBO3,MLST8,SLC19A3,FAM200B,ICAM5,TLR4,TPD52,PRMT8,CADM1,CCDC136,ZNF781,XPO1,ZNF708,CELF4,LRP8,FAM47E,SLC17A6,AMN1,CAMK1G,IFT88,LAS1L,FAM198A" MicroRNA hsa-miR-140-3p:PITA hsa-miR-140-3p:PITA_TOP PITA 9.01E-46 5.06E-42 2.71E-45 2.49E-44 96 329 "NDRG3,USP31,GPR158,LRRC7,GPAM,BSN,LDLRAD4,CANX,USP6,ZMYM4,QKI,AKAP5,SLC35F1,NCAN,SOCS5,HDAC4,SIRPA,SRGAP3,DNM1,NR1D2,CPEB2,DRP2,GOLT1B,KMT5B,EGR3,TENM1,PLEKHA1,ANKRD13B,FOXG1,SGIP1,AFF2,STAG2,DNER,AHDC1,PCDH17,SPIN1,PCDH11X,GRM2,WIF1,MIER3,HLF,KCNB1,KCNMA1,KIF5A,MAP2,MEIS2,PABPC1L2A,FXYD6,NFYA,NOVA1,TBC1D25,PCDH8,OLA1,PLP1,PURG,SCHIP1,PACSIN1,KANSL1,RASGEF1B,PKIA,VPS13C,WBP1L,PTCH1,KHDRBS2,ROBO2,FBXW7,SCN3A,PPM1E,RIMS1,SNAP25,SOX11,SP4,CDK19,TAB2,NCDN,ZC3H4,PLCB1,SYN1,TCF4,SATB2,DOCK9,AHCYL2,SIRT1,ZFPM2,TLL2,RBFOX2,TRPS1,USP1,ZBTB38,SYNC,URM1,PDSS2,GOPC,VANGL2,FRMD6,SOCS4" MicroRNA hsa-miR-106a-5p:Functional MTI Functional MTI miRTarbase 1.12E-45 6.31E-42 3.37E-45 3.11E-44 143 714 "ADAR,FMNL2,FZD9,SORCS2,ZNF578,MARCH4,KIF6,SEMA7A,APC,APP,ARHGAP5,CAPRIN2,ATM,ATP1B3,RNF182,MTMR9,BCL2L2,LDHD,MTMR3,NIPA1,FOXK1,MAP7,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,ZNF385A,CPS1,ENTPD4,SOCS5,UBXN2A,DCAF8,KIAA0513,SIRPA,DNAL1,YTHDC1,PLEKHM1,FBXL5,CEP170,RABGAP1L,SLC12A6,DPYSL2,DNAJB6,HIPK3,FEM1B,SH3GLB1,KMT5B,ABI2,EIF4G2,IRAK4,ELAVL2,CERCAM,BSCL2,RTN3,TLR7,KATNAL1,F3,WAC,ACSL4,GTF2IRD2,POLR1B,SUCO,TPK1,TRAF3IP2,SALL3,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,CBX1,LUZP2,FUT10,NR3C1,MFSD2A,FICD,HAS2,HMGB1,KCNB1,KCND3,ARHGAP12,GPR155,SESN3,NBL1,CNOT4,PDPK1,PFKFB2,PFKP,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,MAPK9,SLC22A23,PXK,OCIAD1,RAB5B,CEP97,ZNF532,CYB561D1,TMEM100,ATAT1,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,RPH3A,RUFY2,FAM126B,SON,SP2,SP4,EMC1,SMOC1,STAC2,WWC1,TCF7L2,GPRIN3,ZMAT3,NACC2,CBX5,PARD3,TPM4,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-604:mirSVR_lowEffct hsa-miR-604:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.26E-45 7.08E-42 3.79E-45 3.49E-44 122 531 "EMILIN3,NCKAP5,NBAT1,SYS1,PLEKHG5,GALNT16,SLITRK1,SLC12A5,BEND6,HECW2,ALCAM,PPFIA1,USP37,MIER1,SEMA4G,LINC00173,CAPRIN2,NCOA1,DYNLL1,RIPK1,AP1M1,BSN,CA4,CAMK2G,PRC1,DCLK1,IGDCC3,MFSD4A,SEC31B,NCOR2,PLCH2,PDE4DIP,DZIP3,CTH,RUBCN,ARMCX4,COPS7A,LYPD1,DNM1,RPS6KL1,CPEB2,TMTC1,SORBS3,ING4,EPB41L2,ERCC2,ZNF461,POLK,FOLH1,NBEA,RASL10A,CELF1,ARPP21,SEPT9,RNPS1,CCDC184,GRIA4,GRIK3,ADAMTS13,CIT,CLASRP,MFSD2A,PSIP1,ICA1,MYLK2,IL11RA,NME9,KCNK2,HECTD2,MYT1,NPY,NPTX2,NRGN,PBX1,PCSK5,PFKFB3,A2ML1,PLIN1,PPP3CA,CASTOR1,RAB5B,CCDC40,FAM66C,GTDC1,ZFHX4,S100B,SEMA6D,DRAXIN,SCN8A,TRIM46,FOXRED1,SH3GL3,NTNG1,SHMT2,SMTN,SLC11A1,RCOR3,PDZRN3,PBLD,SS18,SSPO,SYNE2,SYN1,KAZN,CAMTA1,TAL1,SMG6,HIF3A,TK2,TNFRSF1B,R3HDM1,SMUG1,UBE2H,PITPNB,CLIP2,NPDC1,XRCC4,ANKS1B,CA10,RNF170,PIANP,NETO2" MicroRNA hsa-miR-7-5p:TargetScan hsa-miR-7-5p TargetScan 1.86E-45 1.04E-41 5.57E-45 5.13E-44 106 405 "CSMD3,ELFN2,ADD2,RNF150,HECW2,OGT,DGKD,PPFIA3,ARRB1,RASL11B,ATP2B2,CADM3,KSR1,CACNB4,DIRAS1,HAP1,CAMK2D,DLGAP2,FOXN3,CNOT8,IGLON5,CNN3,HS3ST5,CRY2,NCOR1,CLIP3,FAM131B,G3BP2,CALN1,CPEB2,DPYSL2,CACNG7,GPR61,EGFR,ABI2,EGR3,ERBB4,ECSIT,MED12L,HPCAL4,ANKFY1,GABBR1,GABRA1,GGT7,GOLGB1,BTN2A1,COQ10A,KLF12,NKD1,CDH20,KCNA6,KCNB1,MAP4,ADAM11,CCDC80,NFIA,NOVA2,HCN1,CHAMP1,PAX6,PDE4A,PDE4B,PDE4D,PIK3CD,CCSER2,PLEC,MAPKAP1,POU6F1,CRLS1,PKIA,PRKCB,MAPK4,MAPK10,RAB5B,OXR1,ARID4A,ALG9,RIMKLA,SATB1,ATXN1,ATXN7,SCN2B,FAM19A1,KIF16B,AMBRA1,KIF13A,FAM126B,CLASP2,NXT2,GSE1,FAM168A,NECAB1,PLCB1,ANKRD28,ANKRD12,FAM208A,HHIP,PPIL6,LRTM2,CADM1,FLRT2,RBFOX3,GAL3ST3,RGS7BP,RSPRY1,FXR1" MicroRNA hsa-miR-1285:PITA hsa-miR-1285:PITA_TOP PITA 2.14E-45 1.20E-41 6.42E-45 5.91E-44 78 214 "SDE2,CSMD2,FZD9,NLGN4X,HECW2,APBB2,USP37,BTRC,FOXN3,COL4A5,CSNK1G3,RIMS4,ERC2,ZC3H11A,DLG2,DPYSL2,CNNM1,EGR3,TENM1,DMTN,SRRM1,ATP8A1,AGAP2,GABRA5,CHL1,GABRB3,JPH4,CPLX2,RUNDC3A,TTBK1,PCDH11X,KDM2B,LPAR4,TOX2,KLF12,BACH2,MIER3,IBA57,LRRTM3,KCNB1,KCNK2,MEF2C,MPP2,RSPO2,MDGA1,MYBPC1,GDAP1L1,PIK3R1,ANKRD16,FAT3,NXPH1,PPP2R2B,PPP3CB,RASGEF1B,FAM120C,MARCH1,ARID4A,RGS4,CASC3,ITSN1,CHD9,WDR37,RIMS1,SNCA,SP2,LHFPL4,SS18,STX1A,WWC1,SATB2,TCF12,ITGB3BP,THRA,RBFOX2,SMARCAD1,EMSY,WIPF2,FRMD6" MicroRNA hsa-miR-3184:mirSVR_highEffct hsa-miR-3184:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.71E-45 1.52E-41 8.12E-45 7.48E-44 127 577 "TTYH1,ACLY,SYS1,ARID1A,SLC12A5,ERMN,ADRA1B,DPY19L2P4,AP2A1,ZNF608,SPOP,FAM135A,CDK13,ATP6V1G2,ADAM15,BTK,KALRN,USP2,CDC42,CPNE6,PPT2,CLCN4,CLTB,FADS2,SLC25A27,AATK,FEZ1,PDE4DIP,ECE2,DGKB,DBI,SPATA2,HEPH,MAGI2,LYPD1,DDX46,G3BP2,TMCC2,ATN1,DYRK1A,FCF1,EFNA3,YAF2,EGFR,USPL1,EIF1,EPHB1,RAB9B,SIRPB1,EZH1,PTK2B,FGFR3,AGAP3,FOXM1,CGREF1,CHL1,B4GALNT1,LRRC37A6P,RUNDC3A,GLYR1,GLUL,POLL,STON1,RFFL,GRIN2D,GRM1,AP4S1,HSPA1L,INPP5B,KCNC1,MDM4,MN1,MT3,NNAT,SLC11A2,OGDH,PDYN,GPR173,ZNF655,PLTP,EPB41L4B,PPARA,PKIA,MAPK10,BCAS3,SIDT1,CNTLN,TMEM260,PTPRB,PYGM,YY1AP1,ST6GALNAC6,RTKN,TRIM46,SELL,ITSN1,FERMT1,HKDC1,AMBRA1,SLC4A3,SLC14A1,SLC20A2,SLC22A4,KDM4C,ERC1,SPART,C11orf87,ATP10B,RGL1,STXBP1,PLCB1,SMG6,NAT16,OBSL1,USP32P1,RELL2,PRRT1,DCBLD1,RPRM,OSBP2,ZNF177,EML6,DNALI1,LINC02210,HPS4,CASC15,MSRB3" MicroRNA hsa-miR-4259:mirSVR_highEffct hsa-miR-4259:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-45 1.55E-41 8.27E-45 7.62E-44 130 603 "NCKAP5,XKR4,NDRG3,DSCAML1,SNX32,RTL9,KIAA1324,SPOP,MARCH4,ANK3,APC,ALS2,APOC2,TNRC6C,MIER1,SEMA4G,MARK4,NCOA1,ATP2A2,BACH1,NRP2,CACNA1D,CBLN1,USP2,TIGD7,CHN2,RAB28,PPT2,COL4A5,ZFP28,CHD1L,SEC31B,SLITRK5,CTNND1,BOC,MYADM,KATNAL2,DCT,HEPH,MYEF2,HP1BP3,SV2A,DLX1,RAB39B,ATN1,MBNL2,C8orf37,EPB41,ZNF549,CLVS1,ZIC4,CHST15,FDFT1,SPSB4,PRKAG2,CAP2,ZCCHC17,UFM1,STAG2,MEGF10,DISC1,SRCAP,BRD8,ZNF276,TNRC6A,PRLHR,CCDC184,GRIA1,GRIA4,GRID1,RFFL,GRIK2,KAT7,FAM222A,MAEL,HMGCR,TCEAL6,USP54,INSM1,KTN1,INSYN2,PPM1L,TCEAL5,SLCO1C1,OPHN1,P2RX7,PCSK2,JAKMIP1,PLP1,PMP22,TMEM260,PTPRH,TMEM255A,GAL3ST4,ZYG11B,GTDC1,FBXW7,RPS6KA2,KCNIP1,ATXN2,ITSN1,SLN,SOX2,KDM3A,SP2,NPAS3,SAMSN1,EPB41L3,STAU1,SEPT8,ADHFE1,KLHL7,SYN2,ZEB1,SPX,TIAM1,R3HDM1,FLRT2,CCDC14,SF1,FMN2,CELF4,RNF103,PCDH15,SLC17A7,LINC00632,ST7,UBE3B,FXR1,NETO1" MicroRNA hsa-miR-338-3p:TargetScan hsa-miR-338-3p TargetScan 2.90E-45 1.63E-41 8.67E-45 7.98E-44 96 333 "ADORA1,RNF150,ESYT2,MTUS1,KCTD16,KIAA1324,LRRC7,MARCH3,MARK4,N4BP2L1,NOL4,BCL2L2,BSN,CACNA2D1,CACNB4,CAMK2A,CAMK2G,KIAA1549L,COX4I1,SEC31B,AKAP12,HAPLN1,OSBPL3,FAM169A,PPP1R16B,ARHGAP32,DGKB,IP6K1,POM121,DLG2,CDON,ABI2,COPS4,DMTN,AMOTL2,CINP,CHL1,BRPF3,CPLX2,GBX2,RAB30,PCDH11X,GPD2,GRIN1,PTPRT,FRMD3,NCKAP1L,HPSE2,HNF4G,IGF1,INSM1,METTL21A,KCNA4,KCND2,KIF2A,MAP2,MAPT,MBD1,MEF2C,MOG,DBNL,NEUROD1,NFIA,NOVA1,HCN1,PBX1,PIRT,PPM1B,PPP1R1A,PTN,MORC4,ARHGEF10L,SEC61A2,FBXW7,KIAA0895L,HUNK,SALL1,CPEB3,RPH3A,RIMS1,MBD5,MYT1L,MYCBP2,ERC1,LARP4,FAM168A,MMS19,AP4E1,CADM1,FRRS1L,GDPD5,PPP1R3F,C12orf4,RGS7BP,JMJD1C,LAS1L" MicroRNA hsa-miR-532-3p:mirSVR_highEffct hsa-miR-532-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.69E-45 2.07E-41 1.10E-44 1.02E-43 132 622 "KCNH8,ARID1A,ERMN,AP2A2,KIAA1324,ALCAM,VAT1L,PLA2G4C,CAPRIN2,ATP1A2,EIF4G3,ATP2B1,ALDH7A1,CALB1,CAMK2G,CANX,CLDN10,LDB2,CDH2,HECTD1,NIPBL,FAM149A,SUMF2,CHD1L,SEC31B,SEC24C,MICAL2,ERC2,KATNAL2,IST1,ZEB2,SNAP91,CHRDL1,NYAP1,DOCK2,RCAN1,AASDH,PHC2,KLHL5,CELSR3,PHF20L1,APH1A,KMT5B,ABI2,SPEG,WAC,ZIC4,SLC9B2,FER,FOXF2,NPTN,ATP6V1H,CELF1,DKK3,RAPGEF6,GAP43,GART,NEU3,TUBGCP4,CBX1,ADGRA3,GRIA4,PLCD4,CFAP126,C2orf72,ZIC5,KCNK2,C2orf80,SMAD9,MBD1,MBNL1,MIA2,PPM1L,ZNF680,CTNNA3,NEK1,OPHN1,P2RY1,PBX1,PDE4D,GNG2,NLGN3,XRN1,PURG,IRX1,PPP2R5E,PRKACB,MAPK8,PSD,FAM66C,ZCWPW1,CRTAC1,RGS12,CARF,RYR3,DRAXIN,AMBRA1,CNKSR2,ST3GAL3,CTXN2,ABLIM3,SLA,ENKUR,PEG10,SEPT8,ACSBG1,FGD4,COBL,ANKRD12,DDHD2,EHBP1,ZFP90,SZT2,USP32P1,CRB1,ITGB3BP,TMPO,SYNPO2,PRMT8,FNDC5,RPRM,SPIRE1,UPF3A,STMN4,ADAMTS9,PPP1R3F,KCNAB1,PDSS2,GOPC,MSRB3,SLC4A10,FAM198A" MicroRNA hsa-miR-653:PITA hsa-miR-653:PITA_TOP PITA 3.91E-45 2.20E-41 1.17E-44 1.08E-43 92 306 "ARID1A,SLITRK1,ADD3,PCDH19,FAM135A,CDC42BPA,CDK13,ATP2B1,B3GALT2,JAZF1,CAMK2D,KRIT1,C1orf52,REPS2,CDH2,KMT2C,ZFP28,CLOCK,SOCS5,RIMS2,PLEKHM1,SPOCK3,DLG2,MBNL2,RGS17,SRRM1,EPS8,TAOK3,ATP8A1,SEC24B,IP6K2,AGAP2,DACH2,ST6GALNAC3,PHYHIPL,CAB39,SPIN1,GPM6A,GRIA1,CIT,SOX21,MBNL1,PPM1L,NCAM1,ZC3H12B,RCOR2,NEUROD1,NFIA,NOVA1,HCN1,PBX1,KCTD15,SCHIP1,KANSL1,PRKCB,OCIAD1,PTPRZ1,SH3TC2,RDX,ZNF532,ATXN1,SCN2A,SCN3A,CHD9,PPP4R3A,SLC8A1,CCDC88A,TET1,RCOR3,FAM126B,SON,SOX5,SP4,SSTR1,LARP4,POPDC3,TCF4,RPGRIP1L,RALYL,SIRT1,TPM1,UBTF,FLRT2,WIPF1,SF1,ZNF711,LYPD6,EMSY,CADM2,PRDM10,RGS7BP,MSRB3" MicroRNA hsa-miR-340*:mirSVR_lowEffct hsa-miR-340*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.33E-45 2.43E-41 1.29E-44 1.19E-43 152 806 "AS3MT,PLEKHH1,ADORA1,TAOK1,ZNF687,AMPD2,FGD2,PKP4,APAF1,KCNAB2,DDO,PHYHD1,AMER3,PPFIA3,APP,CDC14B,NUMB,ATM,DPY19L3,CARMIL3,KSR1,LINC00906,CALB2,SPAG9,CBS,KYAT1,METTL6,CD81,ZFYVE9,FBXO7,TJP2,ACBD5,CSF1,VAC14-AS1,PHACTR3,GREB1,PUM1,DCAF4,ZFYVE16,LIN54,ZEB2,CNIH3,HP1BP3,SRGAP3,KIF19,SLC29A4,DOCK2,GNE,TOM1,DNAJB6,PHC2,GPR61,RASA4,AASS,EPB41,VPS26C,ABCA8,MEX3B,CINP,USP21,ERGIC3,KBTBD12,ARPP21,IP6K3,SYT17,GHR,TXNL4A,LUZP2,GNG4,PRLHR,DIDO1,GRIA4,RFFL,GRIN1,KIF3A,CLASRP,ZBTB49,RABL2A,CPT1C,CELF5,LIX1,IL11RA,ZNF678,TUBB2B,STMN1,NCOA7,LOC100128239,MAP4,SYT9,MIA2,AFDN,FXYD6,NELL1,SLC11A2,ZNF713,PIK3CD,A2ML1,SIDT1,PTPRE,PEX2,CCDC40,ZNF493,GTDC1,RGS12,SEC61A2,DCUN1D2,MYH14,ALG9,EPHA10,ZNF568,STX1B,ZNF331,S100B,LRFN5,ITSN1,DHX30,SLC6A8,ZNF430,SNRPN,FNBP1,CDK19,ZBTB43,MCF2L2,ZSCAN29,SEPT8,NECAB1,ADAMTS17,CAMTA1,PDLIM2,IQCE,TMEM136,TNS2,HIF3A,ERCC6L2,C5orf64,TPM3,RGMB,ZNF346,TSN,CADM1,FAM181B,KLC2,XRCC4,POLR3H,UPF3A,PRDM2,SEMA3B,SIGLEC10,FIP1L1,CASC15,ADAMTS10,SPATA13" MicroRNA hsa-miR-764:mirSVR_highEffct hsa-miR-764:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.54E-45 2.55E-41 1.36E-44 1.25E-43 124 554 "ASIC2,SLC44A5,KLHL13,AGT,KIAA1324,ALAD,CDK13,NCOA1,N4BP2L1,NOL4,NRP2,KSR1,DST,ARHGEF7,IL33,KALRN,CAST,CCNH,SLC16A4,AIFM1,CD81,CLTC,AKAP6,COX4I1,TRIM69,SNCAIP,NCAN,TCAF1,SRGAP3,DTNA,SGK2,PHF20L1,ELN,MFSD10,COQ7,RCAN2,ANKMY1,WAC,SCML2,TOMM40L,FGFR1,UBE2E3,FAM49B,USP21,CELF1,ZNF512,FYN,MEGF11,GAD2,GATM,GCNT2,SRCAP,LOXL3,PRDM5,CLASRP,METTL21A,KCNN1,KIF5C,LIMS1,NAT8L,MARK1,NINJ2,NOVA1,DNHD1,TBC1D25,IGSF11,SNTG1,PCDH8,PDYN,SLC10A4,FAM216A,PRIMPOL,MAPKAP1,PACSIN1,DRAM2,PPM1B,PTPA,RASGEF1B,MAPK10,SIDT1,ANKHD1,PEX2,PEX5,ENOX1,PRIMA1,SLC25A36,RNASEL,RPRD1A,RORB,BAALC,KIAA0895L,TCP11L1,ATAT1,CLIP1,NCBP3,ITSN1,HKDC1,ABLIM3,DHX30,RUFY2,ELMO2,IFT122,FAIM2,SOX5,BEX1,ZNF302,NUDT10,SYT1,ZEB1,SYNE1,ZFPM2,TJP1,PDSS1,UBE2H,TOM1L2,P2RY12,GPR158-AS1,TMEM237,PRDM2,STOX2,NAV3,DNAH10,JMJD1C,RNF146" MicroRNA hsa-miR-139-3p:mirSVR_lowEffct hsa-miR-139-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.23E-45 2.94E-41 1.56E-44 1.44E-43 114 472 "CSMD2,RNF150,TXNDC16,BIN1,MADD,ZFYVE28,CADPS,ASPH,ASTN1,TMEM108,BLM,GPR146,GPC2,CACNA1B,TRIM41,SYT6,MAP7,CBS,LDB2,ENTPD2,ZBED1,CDC42,SULT4A1,CSF2RA,OLIG1,EDN1,SIDT2,GOLGA7,EPHB1,RASL12,EFEMP1,RACK1,FLT1,SLC37A3,TPK1,RASL10A,DLL3,GAB1,GAD1,GGT7,ZNF638,GP1BB,GRK4,GRIA2,GRIA4,CACFD1,GRM5,PSIP1,ARHGAP36,HNMT,HSD17B1,LRRC25,TMEM240,KIF5A,FGFBP3,LDLRAD3,MEIS1,MSI1,FXYD6,NEUROD1,NPTX1,GPR88,LOC100128398,PIK3R1,FXYD1,RC3H2,FSD1,PPP2R5C,PRKCZ,ZIK1,STRC,NWD1,ZYG11B,DUSP15,ERI2,RFX2,CARF,TMEM100,GLDN,STK32B,SOX8,FERMT1,SHMT2,HKDC1,SLC8A2,SEPHS1,SLC11A1,ANKRD36,UNC80,CLSTN2,STX1A,STXBP1,DMXL2,CUX2,NAT16,PUM2,USP32P1,VWCE,TK2,NPL,PRMT8,SMUG1,TRIO,SSBP2,HIRA,UBTF,OSBP2,NPDC1,POLR3H,EML6,FTSJ1,MPPE1,UBE3B,TMEM63C" MicroRNA hsa-miR-499a-5p:TargetScan hsa-miR-499a-5p TargetScan 5.41E-45 3.04E-41 1.61E-44 1.49E-43 93 314 "ABAT,KCTD16,OSBPL1A,LRCH2,PPFIA2,APC,KIAA1614,CDK13,DDX3Y,MTMR3,CACNB2,PTBP2,CD38,CDC27,CDH2,CFL2,RAB3C,QKI,ACBD5,C2CD2,CNTNAP2,GREB1,FAM131B,SCRN1,DNAL1,DCC,MYEF2,HP1BP3,MTX3,ABI1,DNM1L,EBF1,RBM12,PLXNC1,EIF4G2,EIF5,ELAVL2,ELAVL4,EPB41L2,EPHA5,RRAGB,FOXG1,PCYOX1,CELF1,FUT9,FYN,GABRA1,CHL1,AHCYL1,FAXC,GLYR1,EML4,IL1RAPL1,SCRG1,MSL1,C5orf24,LRRTM1,KCNN3,LIMS1,MEIS1,MMP16,NOVA1,CLDN11,PDE3B,CDK14,PPP3CA,PPP3CB,PRKAB2,PTPRG,RNF220,PBRM1,FBXW7,SATB1,CSRNP3,SCN2B,FNIP1,HSPA4L,CHD9,FNDC3A,RIMS1,CDK19,CAMTA2,POGZ,FAM168A,RALYL,PSD3,LRRC8A,PRR18,REEP1,ANKS1B,LRP8,EVI5,NAV2" MicroRNA hsa-miR-769-5p:mirSVR_highEffct hsa-miR-769-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.56E-45 3.12E-41 1.66E-44 1.53E-43 124 555 "KCNH8,ARID1A,SLITRK1,PTCHD1,FAHD2CP,C1QTNF1,CFLAR,SYNJ1,VSTM2A,CLDN10,LDB2,LGI1,RCBTB2,RGS6,APPL1,IST1,C8orf34,HP1BP3,BLOC1S6,GSDME,HS3ST4,ABCC9,E2F5,FAM135B,CNNM1,FSD1L,SIDT2,KMT5B,CERCAM,DCTN4,EN2,ZIC4,CEP78,FER,SLC37A3,ZMAT1,RAPGEF6,SIGLEC8,DISC1,KIAA1841,NEU3,PCDH11X,GOLGB1,GRIA2,ZNF496,CIT,ZBTB49,ADAMTS6,GPR45,SYNPO,TCEAL6,SMAP1,FAM95B1,NME9,JAK1,KCNK2,KLC1,SMAD1,CLEC18A,LYPLAL1,MBD1,MOBP,MOG,TAGLN3,RTL5,VWA2,DNHD1,NTRK3,NUMA1,OPHN1,P2RY1,PCDH9,PCSK5,BEST3,HERC2P3,DUSP26,GDAP1L1,PLCL1,PLP1,LRP12,POLR2F,CRLS1,GRAMD1C,HYDIN,SAMD9,CYBC1,SYTL2,PXK,TMEM260,SH3TC2,CCDC102B,CNTNAP3,S100B,SGK1,ITSN1,AMBRA1,ANKRD6,ZNF365,SLC1A7,SLC6A1,KANSL3,SLC22A4,ZNF415,ADHFE1,WSCD1,WDR7,USP32P1,HHIP,HEY1,RIMBP2,TPD52,TPM1,TRIO,FNDC5,RUSC1,TSC1,TBC1D15,TCEAL7,SMARCAD1,PCDH15,SLC17A7,EPM2A,RGS7BP,SMIM8" MicroRNA hsa-miR-889:PITA hsa-miR-889:PITA_TOP PITA 5.62E-45 3.16E-41 1.68E-44 1.54E-43 88 280 "ACTN1,PCDH19,CEP126,BCAR3,OGT,UPRT,PPP4R4,NUMB,DDX3Y,CACNB4,REPS2,SOCS6,AKAP5,SLC4A7,C2CD2,OSBPL3,ATRNL1,CTNND2,DCAF8,ZFYVE16,DCC,WDR20,ABI1,DNAJB6,EDIL3,GPHN,ETV1,ZIC4,FGF12,CAMSAP1,DENND2A,NCKAP1,GLS,GLUL,GPR22,MIER3,NEGR1,DHX35,C5orf24,SCRT2,INSM1,ARHGAP12,MAN2A2,MBNL1,MITF,MYCN,NRCAM,OLR1,PCSK1,ZNF655,MAPKAP1,RC3H2,MINDY2,MTMR10,PTPRB,PTPRD,KHDRBS2,UBR7,PCMTD2,MCMBP,SEMA6D,MAGI3,SLC6A1,CCDC88A,SLC12A2,SORCS3,FAM219A,PDZD2,VPS13A,CAMSAP2,FBXW11,TBX15,TCEA1,TCF4,SATB2,CUX2,TRIM2,SYNE1,C18orf54,TRPS1,USP1,VSNL1,ZIC1,ZBTB38,WNK1,PHTF2,NETO2,RNF146" MicroRNA "CACTGTG,MIR-128A:MSigDB" "CACTGTG,MIR-128A:MSigDB" MSigDB 7.30E-45 4.10E-41 2.17E-44 2.00E-43 93 315 "ARID1A,ADCY2,AK2,PITPNM2,APBA2,GPAM,CDC14B,TMEFF1,SPTBN4,CHRD,DPY19L3,CA12,DIRAS1,CANX,FOXN3,SOCS6,HECTD1,NIPBL,ARHGEF6,CNR1,ARMC8,CABP1,LETMD1,ZNF385A,CSF1,RGS6,RIMS3,SPATA2,ELMO1,SV2A,ARRDC4,DMTN,UBE2E3,MEGF11,GAD1,GAD2,ARPP21,RUNDC3A,PTPRT,PTPN5,TMEM25,KAT7,MAP4K5,INSM1,ARHGAP12,MDFI,MPP2,MXI1,ZC3H12B,NEUROD1,NPTX1,NPTX2,NTRK3,ZNF827,KCNK10,PDE3A,PDPK1,PIK3R1,CDIP1,RASGEF1B,DIRAS2,RELN,FAM184A,KLHDC8A,RORB,SYNDIG1,SEMA6D,CASC3,PPM1E,SLC6A1,CCDC88A,WDTC1,SP2,SP4,C11orf87,CLSTN2,SS18,NXT2,MAPK8IP3,ELOVL4,SEPT3,SYT1,SYT4,UNC5D,WASHC4,SIRT1,CBX5,ZNF24,CA10,EVI5,NAV3,KCNAB1,VANGL2" MicroRNA "CACTGTG,MIR-128B:MSigDB" "CACTGTG,MIR-128B:MSigDB" MSigDB 7.30E-45 4.10E-41 2.17E-44 2.00E-43 93 315 "ARID1A,ADCY2,AK2,PITPNM2,APBA2,GPAM,CDC14B,TMEFF1,SPTBN4,CHRD,DPY19L3,CA12,DIRAS1,CANX,FOXN3,SOCS6,HECTD1,NIPBL,ARHGEF6,CNR1,ARMC8,CABP1,LETMD1,ZNF385A,CSF1,RGS6,RIMS3,SPATA2,ELMO1,SV2A,ARRDC4,DMTN,UBE2E3,MEGF11,GAD1,GAD2,ARPP21,RUNDC3A,PTPRT,PTPN5,TMEM25,KAT7,MAP4K5,INSM1,ARHGAP12,MDFI,MPP2,MXI1,ZC3H12B,NEUROD1,NPTX1,NPTX2,NTRK3,ZNF827,KCNK10,PDE3A,PDPK1,PIK3R1,CDIP1,RASGEF1B,DIRAS2,RELN,FAM184A,KLHDC8A,RORB,SYNDIG1,SEMA6D,CASC3,PPM1E,SLC6A1,CCDC88A,WDTC1,SP2,SP4,C11orf87,CLSTN2,SS18,NXT2,MAPK8IP3,ELOVL4,SEPT3,SYT1,SYT4,UNC5D,WASHC4,SIRT1,CBX5,ZNF24,CA10,EVI5,NAV3,KCNAB1,VANGL2" MicroRNA hsa-miR-182*:mirSVR_highEffct hsa-miR-182*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-45 4.22E-41 2.23E-44 2.06E-43 123 548 "ACTN2,ADARB2,KLHL32,SLITRK1,ADCY8,SORCS1,PLEKHH1,KLHL13,CC2D2A,SRPX,CARNS1,GPAM,ATM,EIF4G3,SCAPER,MTMR2,LGI1,TIGD7,CFL2,SYNPR,FAM189A2,ARMC8,SLC4A8,CREM,ENTPD4,CRY2,FEZ2,ATRNL1,PNPLA8,CYBB,FGFR1OP2,LIN54,MATR3,DGKB,DDX46,FAM107B,DTNA,FAM78B,AASDH,OLIG2,RCAN2,RASL12,CLVS1,FAM198B,AMZ2,SCML2,DLC1,SLC9B2,POLK,NELFCD,GABRA1,ILDR2,RAPGEF6,ERAP1,ZNF559,GATM,PCDH17,GHR,TCERG1,GNAO1,RAPGEF4,GRIK4,RNFT2,MAEL,ELOVL5,HNMT,NEGR1,FAM95B1,IL6ST,ZNF678,KIF5A,MAP4,MXI1,LYRM9,NF1,NPPA,NUCB2,OGG1,CNTN3,PIK3CD,RETREG2,TATDN3,PPP3CA,TTC13,OXR1,RADX,UBR7,ZNF532,ATAT1,LINC00461,IL17RB,SH3GL3,FERMT1,SHC4,FNDC3A,CNKSR2,ST3GAL3,SLC12A2,MTERF2,TMCC1,SPART,MPRIP,SYN1,TMEM150C,UNC5D,ZFP90,SYNE1,DOCK9,ZNF384,SYNPO2,TRPC3,PPIL6,TTC3,CADM1,ZNF709,VAV2,KCNT2,SLC30A4,RNF103,SMIM8,HNRNPA3,PHTF2,FRMD6" MicroRNA hsa-miR-4264:mirSVR_highEffct hsa-miR-4264:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.51E-45 4.22E-41 2.23E-44 2.06E-43 123 548 "KCNH8,ACADM,CSMD3,AXIN2,PWWP2A,ABCD2,ALS2,DDO,CACHD1,SHTN1,MIER1,SEMA4G,SPTBN4,ARRB1,DDX3Y,ADAM23,KALRN,ZMYM4,LHX2,TMEM155,CNTN1,IQCK,AKAP6,ACBD5,FAM171B,GDA,SEC24C,ERC2,NRSN1,HDAC9,KATNAL2,TCAF1,ARHGAP24,ZFYVE16,IST1,AIF1L,RUSC2,ZC3H11A,SMG7,G3BP2,FAM135B,EEF1D,OLIG2,ENPP6,SIRPB1,ABCA8,KAT8,CAP2,SGIP1,SMC2,FAM49B,DKK3,GALNT15,DISC1,MYOZ2,GFER,ZNF276,GRM1,GRM3,FAM19A2,ATXN2L,GABARAPL2,MSL1,FAM95B1,IL11RA,KCNK2,KIF2A,PAXBP1,MBNL1,LRP1B,MEIS2,MOG,MSR1,SFR1,IGSF11,OCRL,ZNF713,P2RY1,RETREG1,PCDH18,RETREG2,HYDIN,PTPRG,BSDC1,SLC6A15,TMLHE,ROBO2,YY1AP1,FBXW7,ATP8B4,FAM192A,ATXN7,TRA2B,ITSN1,FHOD3,SPHKAP,SLN,SNRPN,TNIK,ZSCAN29,ELOVL4,TMEM150C,SYT1,TAC1,ACSL6,PCDHB3,PUM2,TJP1,C9orf85,AMACR,TRO,DCBLD1,FAM155A,VLDLR,XRCC4,ZIC3,ZSCAN26,SMARCAD1,EMSY,PRDM2,GOPC,FZD3,NETO1" MicroRNA hsa-miR-1266:mirSVR_highEffct hsa-miR-1266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.52E-45 4.23E-41 2.24E-44 2.06E-43 131 617 "ARID1A,ADD2,BRAP,SORCS1,PTCHD1,AK2,GPRASP2,EPB41L5,BCAS1,CADPS,ASTN1,INSYN2B,EIF4G3,ATP2B1,ATP6V0A1,NRP2,PTBP2,CBS,AIFM1,CDH18,CLTA,CLTC,ARMC8,NCOR1,CLIP3,CS,DCAF8,PHF19,KIAA0513,MATR3,DAPK1,PITPNC1,COPS7A,FBXO25,DTNA,FIS1,SNX29,EDN1,RASA4,IRAK4,OLIG2,SEZ6,EPHB1,ANKMY1,CLVS1,NSRP1,PRMT5,FER,FGF11,IP6K2,NOP56,NELFCD,SMC2,NSG2,MSANTD4,ZNF44,GFAP,ADGRA3,NUDT21,GRM7,PSIP1,NXPH2,GPR45,NKD1,KCNA6,KCNK1,KIT,KLC1,ZFYVE27,MARK3,MBNL1,SYT9,KCTD6,MSI1,MTTP,MYO7A,NINJ2,PAH,PBX1,ETFRF1,PDCD2,PDE1C,NALCN,EPB41L4B,MED1,APTX,CNTLN,TMEM260,NKAIN1,SLC25A48,BSDC1,MSANTD2,SLC25A36,ZFHX4,ARMC5,GSTCD,NEK11,TCP11L1,AMER2,LRRTM4,MYO18A,SHMT2,PPP4R3A,FAM214B,ARHGEF40,TSNAXIP1,HECW1,MPRIP,VPS13A,ANKRD28,CAMSAP2,ANO4,TCF7,TIAM1,NACC2,ERCC6L2,TMOD1,NPL,SYNPO2,TRIO,TSN,TTC3,WIPF1,P2RY12,GUSBP1,PCDH20,ZNF189,ANKS1B,UPF3A,PRDM2,LAS1L" MicroRNA hsa-miR-569:PITA hsa-miR-569:PITA_TOP PITA 7.89E-45 4.43E-41 2.34E-44 2.16E-43 82 242 "ADD3,SEMA6A,APAF1,STX16,KSR1,FUBP1,NIPA1,BTRC,CALM1,RUNX1T1,CDC42,CCPG1,CLCN3,MAP4K4,NSL1,SH2B1,PNPLA8,DOCK4,LONRF1,G3BP2,E2F5,SH3GLB1,LPAR6,ELAVL2,PAN3,ENPP6,EYA1,AFF2,TBR1,STAG2,CHL1,GABRG1,MSTN,PCDH17,GNG4,GRM5,ATXN2L,AGFG1,LRRTM3,KCNA4,KCNK1,MAP4,KITLG,NCAM1,NOVA1,PDE4D,PDGFRA,POLG,RAB39A,FAM120C,PTPRZ1,TMEM255A,PLEKHB2,OXR1,RFX3,RIC8B,TMEM206,SALL1,FNDC3A,SEPHS1,TET1,SMARCA4,PDZD2,SOX5,ERC1,NFASC,SRPK2,CLASP2,ATP11A,TRIM2,AP4E1,SGK3,AMOT,TBC1D15,XPO1,ZBTB38,SMARCAD1,SLC38A1,SNX27,PDSS2,KAT6A,SLC39A12" MicroRNA hsa-miR-518c:mirSVR_lowEffct hsa-miR-518c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.40E-45 4.72E-41 2.49E-44 2.30E-43 137 671 "ACTN2,NDRG3,FMNL2,PLEKHG5,PSMG3-AS1,ADD1,BRAP,RNF150,OLMALINC,LRRC7,ALAD,CNTNAP1,AMER3,APP,ASGR1,FUBP1,JAZF1,THSD7A,KALRN,NGB,CANX,BRSK2,PRC1,CCPG1,SRSF11,SOCS6,NRXN1,QKI,SULT4A1,MAP4K4,ARHGEF6,SLC25A27,SLC4A7,MYRIP,ZNF521,AKAP12,ANKRD44,GAPVD1,TOX,KCTD8,DAPK1,SIRPA,DGCR5,RHOBTB1,SRGAP3,DMPK,SLC29A4,CDON,ABCC5,SGK2,SEMA3D,BSCL2,EIF1,MTSS1L,MRPL37,ETV1,DNAJC27,EXTL1,MED12L,IP6K2,NELFCD,SDCBP2,MEGF11,TUBA8,GFAP,PCLO,GRIA1,GRIK1,LINC00839,AGBL5,HSD17B1,LINC00667,KIF5C,SYTL4,MAP6,MOBP,MPP2,LYRM9,MYO6,NME4,NRGN,OPA1,BEST3,PFKFB2,SSH1,GRAMD1C,PTHLH,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,FBXW7,WLS,FOXRED2,SCN2B,SCN3A,HSPA4L,ARX,SLITRK3,BCAN,SLC6A8,SHANK2,CPEB4,PDZRN3,SON,MYT1L,KDM3A,SEPT8,STAC2,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,ZMAT3,ZNF106,RIMBP2,C5orf64,TPM3,TRIO,TSC1,UCHL1,VLDLR,ZNF74,CELF4,ZFAND5,WNK1,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-4268:mirSVR_highEffct hsa-miR-4268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.20E-45 5.17E-41 2.73E-44 2.52E-43 123 549 "ACADM,CSMD3,ADD2,SORCS1,ADORA3,ADRB2,PPFIA2,SUGT1P4-STRA6LP-CCDC180,APBB1,APP,NCOA1,RASL11B,DCAF5,ARHGEF7,DDR1,KALRN,CAMK2G,ZMYM4,PPT2,TMEM155,FAM149A,SMARCAL1,GDA,SNCAIP,PDE4DIP,DZIP3,CFAP61,BOC,GIT2,COPS7A,MED24,SGSM2,DYRK1A,PHF20L1,KMT5B,PCOLCE2,BSCL2,ANKRD13B,ADGRV1,EFEMP1,PRMT5,KAT8,POMT1,APOPT1,DISC1,AHDC1,GJB1,TXNL4A,STARD3,OS9,GRIA4,CLASRP,FAM19A2,HRH3,HMGB1,AGBL5,HSP90AA1,ZNF181,IGF1,RBPJ,IL6ST,KCNJ3,MBD1,MITF,SESN3,MYCN,NFE2L2,CNOT4,NOVA1,ODF2,OLR1,GLIPR1L2,SNTG1,PDGFRA,HMGCLL1,PDZRN4,TRHDE,PRRX1,SEPT4,CEP41,MASP1,SAMD9,SIDT1,BDNF-AS,TMEM260,PTPRE,ACSM5,RALGDS,EXD2,NEK11,RXRG,MIR124-2HG,SCAF8,KANSL3,SLC15A2,SPHKAP,SMARCE1,RCOR3,PDZD2,SP4,DBNDD2,NPAS3,ZNF302,ZC4H2,PRRC2C,TACC1,CAMTA1,ZEB1,FRYL,AP4E1,GALNT17,ARL10,TIAM1,TPM1,TPM2,AMACR,HSPBP1,RPL7L1,CCDC14,CFAP298,ZBTB38,PCDH15,NAV3" MicroRNA hsa-miR-3165:mirSVR_highEffct hsa-miR-3165:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.00E-44 5.64E-41 2.98E-44 2.74E-43 115 483 "RALGAPA1,OSBPL1A,PHF12,PPFIA2,CACHD1,CDK10,ZBTB10,NCOA1,ADAM23,SYNJ2,GYG2,INA,ZMYM4,CDH18,HECTD1,PNKD,C2CD2,LRRC3B,VCAN,PDE4DIP,GREB1,TOMM20,DCC,ARMCX2,RHOBTB1,NTM,DYRK1A,EGFR,EPHB1,KCNMB2,ERCC2,ADGRV1,ACSL4,FGF12,POLK,NOP56,NBEA,CGREF1,TBR1,AP4B1,GABRA1,FAM120B,ZMYND11,PPARGC1A,TTBK1,GLRB,PSRC1,GPM6B,GPR12,TOX2,LRRC75A,USP54,IL6ST,INPP5B,KCNMA1,INSYN2,SYT9,PPM1L,MTTP,NASP,NCAM2,NELL1,NEK1,NF1,NPY,DNHD1,PIK3C2A,SNX10,FAM216A,SPATA6,POU3F2,PPP2R5E,ANKHD1,GTDC1,RFX5,RGS12,KIRREL1,MRAP2,ZC3H14,TCP11L1,KCNIP2,FNIP1,TRA2B,ITSN1,PKNOX2,SLC8A3,EFHD1,ATF7IP,TET1,MAST1,LIMCH1,SOX5,FNBP1,ERC1,CLSTN2,NEK4,CEP68,FNDC9,SYPL1,SMG6,TCF7,C18orf54,RBFOX2,STXBP4,ZKSCAN5,VLDLR,EMSY,CIAPIN1,SIGLEC10,PARP11,PDSS2,DOCK8,TRAM2-AS1,FRMD6,SLC4A10" MicroRNA hsa-miR-3176:mirSVR_highEffct hsa-miR-3176:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-44 5.67E-41 2.99E-44 2.76E-43 122 541 "NCKAP5,GPRIN1,ADD2,SORCS1,SNX32,KCTD16,UNC79,FAM135A,AMPD3,KIF6,TNRC6C,LINC00173,CDK13,ZSCAN18,NUMB,SLC2A11,DST,JAZF1,IL33,CALB1,USP6,KCNAB3,CDH8,TIGD7,LY86,AKAP7,SLC4A8,MYRIP,ZFP28,SEC31B,FEZ1,CST3,CTNND2,ARMCX4,RABGAP1L,DOCK2,SLC12A6,DPP6,FARSB,PLEKHA1,BSCL2,NRN1,GORAB,GTF2IRD2,FGF14,POLK,POMT1,CGREF1,DOT1L,COPS8,RAB30,PSRC1,MAEL,VSIG4,ZNF181,DISP2,LIMS1,NCOA7,TM6SF1,CTNNA3,NF1,SLC11A2,OCRL,PDE3B,GPR85,PKM,FAM216A,PLIN1,SEPT4,TMEM104,TMEM260,RAD52,ATG16L1,FAT4,MORC4,GTDC1,PBRM1,CARF,UEVLD,MCMBP,GLDN,HSD11B1L,CLIP1,FAM182A,AP1AR,FAM19A1,CTXN2,RUFY2,RIMS1,SON,SP4,NPAS3,TAB2,SSTR2,ERBIN,SYNE2,COBL,SYT4,ADGRL3,PCDHB4,ARHGEF12,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ARL10,TIAM1,NR2E1,R3HDM1,TP53BP1,CADM1,PITPNB,PLEKHH2,GUSBP1,ZIC3,TRIM9,PRDM2,IFT88" MicroRNA hsa-miR-298:PITA hsa-miR-298:PITA_TOP PITA 1.19E-44 6.68E-41 3.53E-44 3.25E-43 86 269 "CSMD3,NDRG3,NDRG2,SEMA6A,ALCAM,ANK1,APBB2,APP,ARHGDIA,ZBTB10,NCOA1,BCL2L2,CA12,HAP1,CAMK2D,SPAG9,SOCS5,RIMS3,SPOCK2,DCTN1,MYEF2,G3BP2,DLG4,HS3ST4,CPEB2,DUSP9,DYRK1A,EIF4G2,ELAVL2,ELAVL3,EN2,RCAN2,ETV1,DNAJC27,FHL1,CSPG5,AHCYL1,WASF3,PCDH17,PPARGC1A,INSM2,RNF165,HRH3,MIER3,KCNA1,KCNC2,CAMK2N2,MEF2C,MN1,MYBPC1,NAP1L1,NCAM1,PDE4B,ANKRD16,TNPO2,MED1,CEP41,RAB5B,RALGDS,SCN2A,SCN3A,FAM19A1,PRCD,FBXO11,PPP4R3A,CCDC88A,LGI3,LHFPL4,TEX2,CDK19,POGZ,ANKRD28,ADGRL3,ZEB1,TCF12,DICER1,ITGB3BP,SF1,SH3GLB2,ZFAND5,SMARCAD1,WNK1,KCNAB1,WIPF2,RGS7BP,NETO2" MicroRNA hsa-miR-512-5p:mirSVR_highEffct hsa-miR-512-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-44 7.84E-41 4.14E-44 3.81E-43 133 638 "PLEKHH1,AP2A2,TAOK1,GPRASP2,INSYN2B,N4BP2L1,NOL4,BCL2L2,ZNF599,DST,CALM1,PTBP2,CAMK2B,SLC25A14,SPAG9,RCBTB2,CHRM1,CNOT8,PLAA,FAM149A,BTF3L4,ZFP28,GDA,VCAN,ERC2,NRSN1,ZSCAN23,EDRF1,CENPL,DBI,HEPH,B3GAT3,KIAA0753,SNAP91,WDR20,CCDC3,DNAJB6,E2F6,SEMA3D,EGFR,KMT5B,TUBD1,MFSD10,F8,FCGR3A,OLFM1,MEX3B,SYNCRIP,UFM1,CELF1,AHCYL1,GALC,LRRC37A6P,DBF4,TOX3,TNRC6A,ZNF638,CNTRL,GRM3,GYG1,HNF4G,HP,HPR,RBPJ,ITGAM,METTL21A,KCND2,IPO5,LAMP2,VWA5A,MAG,MOG,BLOC1S2,NELL2,NTRK2,PCSK1,TRHDE,MAPKAP1,PPM1B,PPP2R5E,MAPK9,VPS13C,PXK,STK32A,PTPRZ1,PEX5,QDPR,PID1,CEP97,FAM66C,DBX2,RADX,PBRM1,SETD5,ROBO2,RPE65,MAP6D1,TRAPPC13,COPZ1,SH3GL3,CHD9,SMARCE1,IFT122,RIMS1,RBM34,SRPK2,DIP2A,SYNE2,AGTPBP1,FBXW11,DMXL2,SLC19A3,HIF3A,ZFPM2,AP4E1,ASXL3,ERCC6L2,SYNPO2,TSC1,HSPBP1,FAM155A,DNAJC12,USP1,XPO1,EMSY,NAV3,FIP1L1,MVB12B,PDSS2,ST7,PHTF2,ADAMTSL3,TIGD6" MicroRNA "TAGCTTT,MIR-9:MSigDB" "TAGCTTT,MIR-9:MSigDB" MSigDB 1.48E-44 8.31E-41 4.38E-44 4.03E-43 79 225 "SORCS1,PCDH19,OSBPL8,PITPNM2,EPB41L5,CASK,ARHGAP5,ARNTL,STX16,JAZF1,CAMK2G,MAP7,KRIT1,ZMYM4,MAGI1,CFL2,QKI,CREB5,CTNND2,DNAJC6,KLHL3,CPEB2,YAF2,PHF20L1,ELAVL2,GPHN,WAC,MSANTD4,GABRA1,GABRB3,ZMYND11,GPM6A,NR3C1,CIT,SOX21,ZHX1,BACH2,NEGR1,AGFG1,INSM1,ZNF385B,LRRTM1,KCNJ3,KCNN2,KLC1,MEF2C,MITF,MMP16,CCSER2,PCDH18,STRN3,LRP12,POU3F2,CEP41,ZFHX4,RIMKLA,ATXN1,FAM19A1,CPEB3,SLITRK3,CPEB4,SORCS3,LMBRD1,SOX2,SOX3,LRRC4,ERBIN,VPS13A,ATP11A,ATMIN,TCEA1,ZFPM2,TLL2,TPD52,TPM1,EIF4ENIF1,ZIC2,FXR1,SOCS4" MicroRNA hsa-miR-611:mirSVR_lowEffct hsa-miR-611:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.59E-44 8.91E-41 4.69E-44 4.32E-43 109 437 "RALGAPA1,NBAT1,XKR4,AP2A2,TBC1D14,MAP4K3,TNRC6C,MADD,ADAM15,LINC00847,CACNA1B,CACNA2D1,THSD7A,KALRN,LGI1,TIGD7,CHN2,CLCN3,TJP2,PICK1,FAM149A,AKAP6,CSF2RA,CNTNAP2,PNPLA8,DCAF4,ZNF337,NTM,TMCC2,DYRK1A,EDN1,EDNRA,EFNB3,EIF1,ANKRD13B,RTN3,ATP8A1,NOP56,TMEM175,STAG2,MEGF10,SULT1C4,HTATSF1,LILRA2,CECR2,GRIA2,FRMD3,ATXN2L,SOWAHA,SLC35G1,TTYH2,LMO1,AQP11,TM6SF1,MOBP,PTOV1,PABPC1L2A,NCAM1,NFIX,NTRK3,PCMT1,NLE1,PLXNB3,MAPKAP1,PPP2R5C,RAB39A,PIGG,UHRF1BP1,PTPRB,PTPRG,C1orf109,RALGDS,FEZF2,SLC25A36,ZNF532,CARF,RPE65,SATB1,FAM19A1,ASRGL1,SH3GL3,ST3GAL3,SEC31A,ZNF430,CPEB4,LHFPL4,POGZ,ZC4H2,STAC2,KANK1,ADAMTS17,SYN1,SYT4,PDLIM2,ANO4,SIN3B,ERCC6L2,HEY2,TNFRSF1B,RUSC1,UCHL1,PLPPR2,ANKS1B,CSDE1,CIAPIN1,SEMA3B,SLC17A6,UBE3B,DPF3" MicroRNA hsa-miR-3151:mirSVR_highEffct hsa-miR-3151:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-44 1.28E-40 6.76E-44 6.22E-43 122 545 "VWA5B2,AXIN2,SNX32,SUGT1P4-STRA6LP-CCDC180,CACHD1,MADD,ARRB1,CHRD,KIF1A,CACNA1G,OSGIN2,HAP1,CAMK2G,NFS1,AIFM1,CD86,ARHGEF2,ARHGAP33,LARGE1,NUMBL,CHGA,CPNE6,NRXN3,KIAA1549L,PNKD,CRMP1,USP6NL,KATNAL2,TCAF1,HS3ST4,DRP2,MAMLD1,USH1C,YAF2,TMEM35A,RTN3,SIRPB1,F5,OLFM1,SPSB4,POMT1,SMC2,APOPT1,ZNF512,ZNF234,SULT1C4,GLI2,MAP7D2,PCSK1N,GPD2,CECR2,STMN2,PLCD4,GRM7,CLASRP,MFSD2A,AP4S1,ATXN2L,IL11RA,KCNA2,KCND2,LINC00634,MAOB,MBD1,MEIS1,MEIS2,JAKMIP3,MYO7A,SLCO1C1,P2RY1,PRKAB2,PKN2,SIDT1,PYGM,RAP1GDS1,GTDC1,RFX4,SEC61A2,KIRREL1,NEK11,STK32B,NCBP3,COPZ1,BCAN,URGCP,PEX26,MBD5,CABCOCO1,KDM4C,ZC4H2,GANAB,SEPT3,VAMP1,FNDC9,SYN1,ARC,MTCL1,CAMTA1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ITGB3BP,TIE1,SEZ6L,TPM4,ZNF346,TRH,ZMYND8,CADM1,UBE3A,PLPPR2,BEST1,LGI4,SLC17A7,FZD3,CAMK1G,NLRP3,MSRB3" MicroRNA hsa-miR-194:PITA hsa-miR-194:PITA_TOP PITA 2.31E-44 1.30E-40 6.84E-44 6.30E-43 86 271 "ACHE,OSBPL8,PITPNM2,APC,ARHGAP5,ZBTB10,STX16,LGI1,CFL2,CHM,KMT2C,CNR1,BTF3L4,BAG4,SLC35F1,RBM39,SOCS5,ST18,ELMSAN1,SNAP91,DMD,HS3ST2,SLC12A6,DYRK1A,EDN1,MBNL2,ELAVL3,PAN3,NRN1,ATP6V1H,STAU2,OGA,TNRC6A,GRB10,GYG1,KLF12,TJAP1,KCND2,STMN1,MAP2,MEIS2,MIA2,KITLG,MITF,NEUROD1,IGSF11,PDE4D,SERPINE2,NXPH1,PPP3CA,TMEM260,PTPRD,FAM120C,PTPRZ1,KHDRBS2,ZFHX4,SETD5,FBXW7,NCBP3,SALL1,SCN2A,NLGN4Y,ITSN1,NTNG1,CHD9,BTBD3,SEPHS1,SLC8A1,TMCC1,SOX3,SOX5,SOX11,PEG10,CDK19,CLASP2,SS18,SEPT8,SYT4,CAMSAP2,EHBP1,AP4E1,KAT6B,TRPS1,TRIM9,PMEPA1,PARP6" MicroRNA hsa-miR-1826:PITA hsa-miR-1826:PITA_TOP PITA 3.24E-44 1.82E-40 9.58E-44 8.83E-43 74 197 "GALNT13,NLGN4X,MTUS1,SEMA6A,AQP4,CDC14B,ZBTB10,DCLK1,SLC35F1,ST18,USP6NL,EDRF1,RASSF2,KCTD8,MAGI2,MTX3,WDR20,DLG2,DLX1,EPB41L2,WAC,TAOK3,FGF13,NBEA,BRSK1,MTHFD2,DNER,PTPRT,BVES,NCKAP1L,NEGR1,SMAP1,LRRCC1,MARK1,MXI1,MYO6,ZC3H12B,NF1,NFYA,CNOT4,NOVA1,OPA1,PDYN,GPSM2,MAPKAP1,SPATA6,GDPD1,TMEM260,REV3L,SLC25A36,ZFHX4,SALL1,SCN2A,SCN3A,CPEB3,DOCK10,MYT1L,SOX11,NPAS3,STAU1,TTBK2,GANAB,NSFL1C,AGTPBP1,TCF4,TRIM2,NACC2,AMOT,ZIC3,TRIM9,CSDE1,SNX27,JMJD1C,SOCS4" MicroRNA hsa-miR-30a-5p:Functional MTI Functional MTI miRTarbase 3.36E-44 1.89E-40 9.93E-44 9.15E-43 143 734 "CDC7,KIDINS220,AP2A1,OSBPL8,AK2,TAOK1,SEMA6A,MARCH4,PCDH10,USP37,ATM,STX16,ATP2A2,DPY19L3,SEC11C,ST3GAL5,CAST,CARS,SEPT7,CDH2,LRRFIP1,CCPG1,HECTD1,SLC4A7,TBPL1,BAG4,PREPL,CREM,CSNK1G3,CTNND1,SACS,MTX3,TOM1,CELSR3,EGFR,MRO,MBNL2,ASB3,DCTN4,EIF1,EPB41,ACSL4,TUBA1B,TUBB3,SCML2,CHST15,SEC24B,FOXG1,USP16,UFM1,CELF1,PNMA2,MSANTD4,HHIPL1,GAB1,TRAF3IP2,IP6K3,NCKAP1,ATP8A2,NFU1,DBF4,TNRC6A,ZNF638,GPD2,EML4,MIER3,ELOVL5,GABARAPL2,HNF4G,DOCK7,JAK1,STMN1,LIFR,LSS,SMAD1,LYPLAL1,MAT2A,MBNL1,MPP2,MTR,HNRNPM,NAP1L1,NCAM1,NEUROD1,NUCB1,OGDH,OPHN1,GNG2,SERPINE2,CAMKV,PIK3CD,PKM,EXOSC10,PTPA,PPP2R5C,PPP3CA,PPP3CB,MAPK8,SAMD9,UHRF1BP1,REV3L,PRRT2,SEC61A2,RNF220,PBRM1,RPRD1A,SETD5,ALG9,PCMTD2,SARS,SBF1,SLC12A2,SLC12A4,BTBD7,TET1,CPEB4,LIMCH1,RBM34,SON,KDM3A,SP4,PEG10,LARP4,STAU1,ZSCAN29,SYPL1,SLC35G2,NACC2,RBFOX2,TRIO,ZMYND8,UBE2H,XPO1,MKRN3,ZFAND5,DHX33,SLC38A1,VPS35L,URM1,PHTF2,ZDHHC20,FXR1,SLC4A10" MicroRNA "ATGCTGC,MIR-107:MSigDB" "ATGCTGC,MIR-107:MSigDB" MSigDB 3.42E-44 1.92E-40 1.01E-43 9.28E-43 75 203 "SLITRK1,AXIN2,UNC5A,AK2,OGT,ANK1,CNTNAP1,MARCH3,ZBTB10,CHRD,ADGRB1,NRP2,CDK5R1,SYNJ1,BTRC,CACNA2D1,SYT6,RUNX1T1,CHRM1,ARMC8,PPP6R2,DLG4,ST8SIA3,TSPAN5,PHF20L1,EIF5,RASL12,AFF2,NSG1,PHYHIPL,GABRG2,CAB39,TMEM121B,CLASRP,ZHX1,BACH2,HLF,AGFG1,KIF5A,MBNL1,LRP1B,ZC3H12B,NF1,NFIA,NOVA1,PDE4B,CDK14,CAMKV,PIK3R1,PACSIN1,LRRN3,SNRK,BSDC1,RET,RGS4,FBXW7,SYNDIG1,KIF21A,CPEB3,FAM81A,LRRC55,SLC8A2,ZHX3,ADGRL3,SATB2,WASHC4,PSD3,DICER1,ZFPM2,TGFBR3,TPD52,NR2C2,ZIC1,SLC26A10,ADAMTSL3" MicroRNA "ATGCTGC,MIR-103:MSigDB" "ATGCTGC,MIR-103:MSigDB" MSigDB 3.42E-44 1.92E-40 1.01E-43 9.28E-43 75 203 "SLITRK1,AXIN2,UNC5A,AK2,OGT,ANK1,CNTNAP1,MARCH3,ZBTB10,CHRD,ADGRB1,NRP2,CDK5R1,SYNJ1,BTRC,CACNA2D1,SYT6,RUNX1T1,CHRM1,ARMC8,PPP6R2,DLG4,ST8SIA3,TSPAN5,PHF20L1,EIF5,RASL12,AFF2,NSG1,PHYHIPL,GABRG2,CAB39,TMEM121B,CLASRP,ZHX1,BACH2,HLF,AGFG1,KIF5A,MBNL1,LRP1B,ZC3H12B,NF1,NFIA,NOVA1,PDE4B,CDK14,CAMKV,PIK3R1,PACSIN1,LRRN3,SNRK,BSDC1,RET,RGS4,FBXW7,SYNDIG1,KIF21A,CPEB3,FAM81A,LRRC55,SLC8A2,ZHX3,ADGRL3,SATB2,WASHC4,PSD3,DICER1,ZFPM2,TGFBR3,TPD52,NR2C2,ZIC1,SLC26A10,ADAMTSL3" MicroRNA hsa-miR-1277:mirSVR_highEffct hsa-miR-1277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.11E-44 2.31E-40 1.21E-43 1.12E-42 110 449 "TKTL1,KIAA1211,PTCHD1,ZNF608,APBA2,SHTN1,CAPRIN2,NUMB,RNF182,BCHE,NRP2,ST3GAL5,DGKI,LRRFIP1,MAGI1,CDO1,CASC2,MAP4K4,CNN3,IGDCC3,CLIP3,MROH8,EDRF1,PABPC5,HP1BP3,BLOC1S6,POM121,USP3,ABCC5,E2F6,EBF1,EDIL3,SNX29,TSPAN5,RASGRP1,OPTN,PHF20L1,PLEKHA1,VPS13B,RACK1,FGF12,FHL1,POMT1,SMC2,ST6GALNAC3,GABRA1,GABRA5,CHL1,GABRB1,NEK6,MYOZ2,CRCP,PCDH11X,LUZP2,RAB40B,GOLGB1,PSIP1,FAM222A,ZHX1,NXPH2,ZNF491,IGSF1,KCND2,HECTD2,MBNL1,MBP,LRP1B,MOBP,MRPL42,ALDH1L2,LRIT2,NRCAM,PAX6,PCDH9,PFKFB2,PIK3CD,CEP41,HYDIN,MDGA2,ANKHD1,PTPRH,PTPRN2,RFX5,RNASEL,PNMA8A,CCDC102B,HOGA1,SCP2,ELMOD1,NLGN4Y,SH3GL2,SORCS3,SMARCE1,RCOR3,ZC4H2,NKAIN2,DDHD2,CAMSAP2,ACSL6,FAM124A,TPD52,TRPS1,PPIL6,OSBP2,MEAF6,PMEPA1,TMEM163,FZD3,KAT6A,RNF170" MicroRNA hsa-miR-1274a:mirSVR_highEffct hsa-miR-1274a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.75E-44 2.67E-40 1.40E-43 1.29E-42 126 583 "METAP1D,CSMD2,KLHL32,BEND6,TXNDC16,ADGRF5,ALS2,CACHD1,SPTBN4,RGS20,ASPH,NCOA1,N4BP2L1,NRP2,BMPR1B,SCAPER,CACNB2,CALB1,LGI1,CASC2,NRXN1,CS,FEZ1,MICAL2,CSNK1G3,ATRNL1,UBXN2A,CTNND1,USP6NL,BLOC1S6,ZC3H11A,G3BP2,HS3ST4,NR1D2,DPYSL2,DRD1,PDCD6IP,FAM135B,SGK2,GPR61,PHF20L1,MBNL2,AASS,EPB41L2,DENND4A,FAM198B,ACSL4,SCML2,TESK2,ZNF589,ANKFY1,OGA,GALR1,ZNF274,MYOZ2,ZNF638,PCLO,GRM8,SOX21,GPR45,ARHGAP36,MIER3,AGBL5,CFAP126,SMAP1,ZNF678,ZNF385B,NME9,KCNB1,GPR62,CLVS2,KCNJ9,KCNN2,CREG2,HECTD2,ARHGAP12,AFDN,NF1,NOVA1,PDCD2,PIK3C2A,FAM216A,MTRF1L,PPM1B,PPP2R2C,PTH1R,TMEM260,ZIK1,EML5,RAD52,GAL3ST4,RGS3,RIC8B,RNASEL,CARF,GSTCD,KIRREL1,ATP8B4,STK32B,ATAT1,LRRTM4,IL17RB,SFPQ,SUPT20H,SLA,SNRPN,KIF1B,SPART,ATP10B,CLSTN2,NXT2,RGL1,SYPL1,TBX15,SATB2,WDR7,SLC44A1,NPL,ANKRD20A2,FAM155A,CELF4,STOX2,TUBA1A,SNX27,FIP1L1,MARCH8" MicroRNA hsa-miR-938:mirSVR_highEffct hsa-miR-938:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.85E-44 2.72E-40 1.43E-43 1.32E-42 107 426 "ACLY,AS3MT,ADAR,FMNL2,ADD2,ADD3,KLHL13,ADGRF5,AMPD3,APAF1,CACHD1,SHTN1,MIER1,PLA2G4C,DDX3Y,ATP2B1,MPDZ,SEC11C,SLC25A14,DGKI,MAGI1,SRSF11,RAB28,MYRIP,CPS1,PNKD,SEC31B,SNCAIP,PDE4DIP,DOCK4,HDAC9,ARHGAP32,TOMM20,ARMCX4,ZEB2,SACS,NR1D2,GOLT1B,FSD1L,ELAVL2,ING4,TAOK3,FHL1,POLK,MEX3B,NOP56,STAMBP,NPTN,STAU2,GABRA1,RAB30,GPM6A,ADAMTS8,ZNF496,RNF165,FRMD3,ZDHHC15,SMAP1,HTR5A,IRF8,IL12A,MARK1,MMP16,FXYD6,SFR1,NEK1,NUMA1,SPATA6,POU3F2,VPS13C,MTMR10,ZSCAN32,ERI2,TMEM100,FBXW7,FAM192A,ATXN2,ATXN7,NTNG1,FHOD3,ARHGEF40,CPEB4,RCOR3,CAND2,MCF2L2,SEPT3,ANKRD12,ADGRL3,EHBP1,SIN3B,ZFP90,TCF7L2,SLC19A3,SIK3,TIAM1,NR2E1,TPD52,TRIO,FAM155A,WIPF1,SMARCAD1,PRDM8,RGS7BP,HNRNPA3,PHTF2,FAM219B,MSRB3" MicroRNA hsa-miR-7106-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-44 3.09E-40 1.62E-43 1.49E-42 148 784 "DPF1,XKR4,ADAR,RNF157,ADD2,PLEKHH1,CASKIN1,SORCS2,TXNDC16,TRMT9B,ANK1,PHF12,AQP6,PRX,ARRB1,DNAH17,ASPA,TTLL9,SYNJ2,CANX,ISPD,CBS,METTL6,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,LETMD1,MFSD4A,CRMP1,CRY2,NCOR2,RGS6,UBXN2A,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,DNAH9,SLC29A4,PHC2,TMTC1,EFNA3,ABI2,RASA4,EIF4G1,PLEKHA1,ING4,MRNIP,EPB41L1,IGSF6,TRMO,CELF1,PNMA2,KBTBD12,BRSK1,TRAF3IP2,DISC1,SRCAP,AHDC1,CRCP,GLYR1,GLUL,STARD3,GNG3,GNG4,PRRC2B,ZNF496,BVES,IRAK3,SCRG1,AGBL5,ZNF491,SHISA6,IGF1,DOCK7,IBA57,KCND1,KCNH2,SMAD9,MAG,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDE4A,PDGFRA,BEST3,PFKFB3,SPATA6,RETREG2,PACSIN1,FAT3,POLR2F,KANSL1,MTMR10,QDPR,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,EMID1,RXRA,FNIP1,HES6,MYO18A,CLSTN1,SLC1A2,RPH3A,TRIM67,ZKSCAN3,ZCCHC24,SP2,MCF2L2,RAP1GAP2,CAMTA2,FAM208A,TPCN2,USP22,SLC19A3,ARL10,THRA,NACC2,ERCC6L2,TPM3,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,EVI5,CIAPIN1,URM1,NAV2,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-3158:mirSVR_highEffct hsa-miR-3158:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.99E-44 3.36E-40 1.76E-43 1.62E-42 135 664 "SYS1,RNF150,DPY19L2P4,HECW2,HFM1,ANK3,AQP6,MARCH3,BRINP2,ATM,N4BP2L1,ADAM23,CANX,LGI1,SRSF11,PPT2,NIPBL,CHD1L,ENTPD4,CLIP3,APPL1,RIMS2,CX3CR1,GPRASP1,ZEB2,ZBTB24,HP1BP3,USP3,DNM1L,WDPCP,FRY,KMT5B,F3,SMC2,USP21,ARFGAP2,CELF1,NRG3,ZNF512,IQGAP2,CYP46A1,GHR,BRD8,TOX3,LNX1,GPD2,TDRKH,GRIA2,PLPP7,GRM7,GRM8,BVES,HPS5,HLF,HNMT,HTR2A,ZIC5,KCNC1,KCNMA1,KIF5C,STXBP5,KTN1,L1CAM,MBD1,MDM4,AFDN,NCF2,NELL1,SLC11A2,GPR88,PAX6,PDE4D,ENPP2,PDYN,A2ML1,KCTD15,PLP1,HMGCLL1,PMP22,RC3H2,SPATA6,SEPT4,EPB41L4B,PKIA,RELN,VPS13C,PTPRE,NWD1,ZNF493,MSANTD2,RFX5,LRRTM4,SFPQ,COPZ1,ITSN1,ARX,FBXO11,FAM214B,SLC6A11,SLC8A3,SLC14A1,SLIT1,CPEB4,SMARCE1,KIF13A,SOX5,NPAS3,NFASC,TAB2,POGZ,ZSCAN29,SEPT8,TMEM150C,MTCL1,MCF2L,ZFP90,NAT16,PCDHB4,SIK3,TK2,FNDC5,BEST1,PCDH20,CA10,ZXDA,EMSY,MFF,DNALI1,RNF103,SNX27,PDSS2,EPM2A,RTN4,IFT88,CPNE4" MicroRNA hsa-miR-4293:mirSVR_highEffct hsa-miR-4293:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.40E-44 3.59E-40 1.88E-43 1.73E-42 117 508 "SDE2,GALNT13,MTUS1,OSBPL8,AK2,SEMA7A,PPFIA1,SHTN1,ZFYVE28,ARHGAP5,RGS20,ARSF,CAPRIN2,ZBTB10,NCOA1,B3GALT2,ADGRB3,BMPR1B,KALRN,MAGI1,CFL2,PPT2,TPP1,HINFP,CLIP3,PDE4DIP,ARHGAP24,BLOC1S6,MED12,DNM2,CPEB2,DMTF1,DPP6,PDCD6IP,DTNA,PHF20L1,EGFR,RGS17,EPHA5,FGF13,PRKAG2,IP6K2,TRAF3IP2,IP6K3,DISC1,TOX3,ADGRA3,RAPGEF4,DIDO1,LINC01551,GUCY1B1,MAEL,HPS5,CLVS2,KCNK2,MAT2A,MATN2,MID1,MYO9A,NFE2L2,NOVA1,DNHD1,SLC11A2,ZNF655,TRHDE,SCHIP1,SEPT4,HYDIN,QRICH1,TMEM260,STK32A,TMEM231,FAM66C,SLC6A15,ERI2,ZNF532,ROBO2,EPHA10,ACER3,ABCA11P,CLIP1,RMI1,ATXN2,SCN8A,ITSN1,CPEB3,SLC1A6,WDR47,KBTBD4,ATF7IP,SORCS3,INTS9,USP33,TNIK,HECW1,TAB2,NKAIN2,ZSCAN29,ELOVL4,DDHD2,DMXL2,TCF12,WASHC4,FRYL,CYB561A3,ZFPM2,CRB1,MTMR14,CSMD1,PITPNB,CFAP298,ZIC3,FMN2,SLC17A7,DOCK8,ADAMTSL3,TRAM2-AS1" MicroRNA hsa-miR-194-5p:TargetScan hsa-miR-194-5p TargetScan 7.36E-44 4.13E-40 2.16E-43 1.99E-42 94 330 "ACHE,C3orf14,NDRG3,PITPNM2,LRRC4C,CASK,ARHGAP5,MYRF,CAMK2G,CDH2,CFL2,KMT2C,QKI,BTF3L4,BAG4,MYRIP,NSL1,CNTNAP2,PLCXD3,ARHGAP24,MATR3,KIAA0087,ELMSAN1,CEP170,DMD,HS3ST2,DUSP9,DYRK1A,EDIL3,MBNL2,PLXNC1,EIF4G2,PAN3,EPHA5,ERBB4,ANKFY1,ATP6V1H,GBX2,PPARGC1A,GJB1,KDM2B,FERMT2,RFFL,GYG1,PLD5,IL6ST,ITPKB,KCND2,KCNJ11,ARHGAP12,LSAMP,MAP2,MEF2C,MEIS2,KITLG,MITF,AFF1,ADAM22,MYO5A,MYO9A,OPCML,PDE4D,GNG2,NXPH1,PPP2R2C,PTPRD,ENOX1,ARID4A,KHDRBS2,REV3L,GTDC1,RFX3,FBXW7,SALL1,SATB1,ELMOD1,HSPA4L,ITSN1,CHD9,BTBD7,IFT122,LIMCH1,FNBP1,CLASP1,NSD1,HHIP,NACC2,CBX5,CADM1,FLRT2,PMEPA1,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-517c:mirSVR_lowEffct hsa-miR-517c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.86E-44 4.42E-40 2.31E-43 2.13E-42 103 397 "OGT,CCDC146,PKP4,KCNAB2,APBB2,DGKZ,TNRC6C,PPFIA3,LGR5,EIF4G3,CFLAR,BSN,CACNB2,KALRN,BRSK2,USP6,CDK11B,ARHGEF2,DGCR9,FAM189A2,HECTD1,GALNT9,DOCK4,MATR3,KCTD8,DAPK1,DNAJC6,JAKMIP2,ZEB2,LYPD1,SV2B,DTNA,DYRK1A,ATL1,C3orf18,EPHA5,ENPP6,CDHR1,RTN3,PTK2B,FLT1,EFCAB2,DACH2,NRG3,GABRA1,DISC1,COPS8,FERMT2,GPR19,LINC00839,RNF165,GPR45,NKD1,SLC35G1,KIF5C,A1BG-AS1,MOBP,SAMD5,P2RY13,NEUROD1,OXTR,PFKFB4,PFKP,SEMA5B,FTO,SLC36A4,POU3F2,PPP2R2C,PRKCZ,EPDR1,MAPK9,PTPRH,PTPRO,PEX5,RASGRF2,ZYG11B,UBR7,RGS12,KCTD17,LGI2,C12orf49,TRIM46,SHC4,SLC12A2,RCOR3,SNRPN,WDTC1,DIP2A,STXBP1,FGD4,WDR7,UGT8,TBC1D15,SLC47A2,CELF4,STOX2,PRDM8,RNF103,ADAMTS9,MPPE1,WNK2,EPM2A,ACTR3B" MicroRNA hsa-miR-1260b:mirSVR_highEffct hsa-miR-1260b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.23E-44 4.62E-40 2.42E-43 2.23E-42 130 621 "NCKAP5,BRAP,AK2,CDC42BPA,PARG,MIER1,CAPRIN2,SLC2A11,CFLAR,SYNJ2,PTBP2,CD86,CDH2,SOCS6,NRXN2,COG1,HECTD1,LETMD1,MYRIP,CHD1L,RNF14,GDA,SIPA1L1,CTNND1,NRSN1,ZFYVE16,ZNF337,TBC1D5,DBI,DBN1,HS3ST2,DSCAM,TMEM35A,EPB41,EPB41L1,SEZ6,RABEPK,STX2,ZNF391,HSPA12B,FCGRT,FER,GTF2IRD2,FGFR1,SUCO,FOXF2,IQCG,SLC37A3,SORBS1,TMEM107,UFM1,NPTN,NSG1,ARPP21,IQGAP2,DISC1,NEU3,SRCAP,SULT1C4,GFAP,MSL3,ZNF638,TDRKH,LPAR4,GRIA4,PLCD4,GRM7,KIF3A,RASSF8,NXPH2,CFAP126,LRRC75A,IL6ST,INPP5B,ITGAV,KCNK2,KCNN3,KIF5A,ASPRV1,PPM1L,CD200,MSRA,NODAL,CLDN11,OXTR,PAK3,PLCL1,GRAMD1C,GON4L,BDNF-AS,PTPRD,RASGRF2,BSDC1,RET,RGS12,TMLHE,ROBO2,ELP2,RTKN,KCNIP1,RXRA,NCBP3,LRRTM4,SCN8A,FNIP1,FOXRED1,KIF21A,ITSN1,AMBRA1,ZNF365,SLC8A3,CPEB4,DBNDD2,RBM26,ADHFE1,AJAP1,NSFL1C,SYNE2,TCF7,TPCN2,SYNE1,TNR,ZNF384,SYNPO2,AMOT,LYPD6,XKR7,PCDH15,C12orf4,RNF146" MicroRNA hsa-miR-3200:mirSVR_highEffct hsa-miR-3200:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.22E-44 5.18E-40 2.71E-43 2.49E-42 102 390 "SYN3,ADD2,SORCS1,DPY19L2P4,AP2A2,USP35,CCDC146,TNRC6C,ATP2B3,ALDH7A1,RUNX1T1,LDB2,C1orf52,CDC27,CDH8,CLCN3,CNGA3,AKAP6,BTF3L4,CSNK1G3,ATRNL1,RIMS2,DOCK4,ZEB2,KIAA0319,MAGI2,DRD1,DYRK1A,ABCC5,DNM1L,AASDH,USPL1,ACSL4,ZIC4,RACK1,POLR1B,RGPD5,FLT1,SGIP1,C2orf88,PDLIM5,MEGF10,GAD2,GAP43,ERAP1,LYVE1,PCDH11X,KDM2B,GPR17,GRM7,MAP4K5,C1orf94,KLF12,TNFAIP8L3,ITGAV,KCND2,INSYN2,MAT2A,MATN2,MITF,CTNNA3,RSPO2,LOC100128398,PCMT1,ZNF655,PLCL1,PURG,PSAT1,PPP3CB,WDR25,ZIK1,ZNF793,OXR1,RGS3,RORB,ABCA11P,ITSN1,CNKSR2,ZNF365,SLC12A2,SMARCE1,RCOR3,ZNF415,KIF1B,ZBTB43,POGZ,RGL1,ADHFE1,SYNE2,DNMBP,CRB1,ITGB3BP,TJP1,C5orf64,CADM1,UBE2H,AGMO,PCDH15,EPM2A,FZD3,HNRNPA3,SLC4A10" MicroRNA hsa-miR-892a:PITA hsa-miR-892a:PITA_TOP PITA 9.39E-44 5.28E-40 2.76E-43 2.54E-42 84 262 "ADCY2,HECW2,AMPH,BTRC,CAST,SEPT7,EVI5L,CLGN,FOXN3,QKI,MAP4K4,AKAP6,BTF3L4,ACBD5,PNKD,RBM39,SLITRK5,LONRF1,CEP170,SMG7,DYNC1I1,CPEB2,DYRK1A,ST8SIA3,EFNB3,KMT5B,NRN1,ZIC4,MEX3B,EVL,AHDC1,GPT2,MAP4K5,MIER3,KCND2,MBNL1,NAP1L3,NF1,NPTX1,OLA1,NLGN3,ANKRD16,LRRN3,PKN2,PTPRG,TMEM255A,RDX,GTDC1,RGS7,NCBP3,SATB1,CSRNP3,ATXN1,ELMOD1,DOCK10,CHD9,R3HDM2,SLC8A1,TET1,CPEB4,RCOR3,SOX5,FNBP1,PEG10,DDN,SRPK2,KANK1,ANKRD12,MTCL1,CAMTA1,ZEB1,RBFOX2,AMOT,FLRT2,XPO1,XRCC4,ZNF711,KCNT2,SYNC,EMSY,NAV3,WNK3,FAM13C,KAT6A" MicroRNA hsa-miR-1913:mirSVR_highEffct hsa-miR-1913:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.02E-43 5.72E-40 2.99E-43 2.75E-42 111 461 "GALNT16,SLC12A5,CDC42BPA,PI16,CNIH2,APBB1,UPRT,CACHD1,PPP4R4,ARRB1,STK33,DNAH17,DPY19L3,ARHGEF7,CACNA1D,TRIM41,LRBA,LRRFIP1,CDH18,SLC25A27,COX4I1,CRMP1,ABCG1,SEC24C,ZSCAN23,DCAF8,IP6K1,YTHDC1,C8orf34,ZEB2,SV2A,DPP6,EDN3,FCF1,FRY,PHF20L1,BSCL2,SEZ6,EPHB1,DUSP27,TOMM40L,ZSCAN30,FDFT1,IP6K2,EFCAB2,WDR83,TRIM16,CGREF1,OGA,STAG2,GABBR1,NEU3,DCLK2,PLCD4,ADAMTS8,AP4S1,RNFT2,WIF1,SOWAHA,KIF5A,KIF5C,KLC1,L1CAM,MTR,MXI1,LYRM9,SETD4,OPHN1,CAMKV,PIK3R1,HMGCLL1,PNMA3,PPP5C,CNTLN,MTMR10,STK32A,ZCWPW1,RGS4,RPRD1A,ZNF532,TMLHE,SCN8A,COPZ1,HKDC1,CNKSR2,FAM214B,SLC9A5,SORCS3,HECW1,DBNDD2,TSPYL2,TAB2,SS18,GANAB,FGD4,SEMA4A,TBCEL,THRA,TPM3,ELP5,TRPC1,ZMYND8,CADM1,ZBTB14,ZNF711,INTS3,PRDM2,DNALI1,PARP6,WNK2,HNRNPA3" MicroRNA hsa-miR-382:PITA hsa-miR-382:PITA_TOP PITA 1.18E-43 6.65E-40 3.47E-43 3.19E-42 86 276 "NDRG2,PWWP2A,BEND6,GPR158,PKP4,GPAM,MIER1,DDX3Y,EIF4G3,ATP2B1,SOCS6,LHX2,KMT2C,CLTC,QKI,CRHBP,SEC24C,TOX,MATR3,YTHDC1,DMD,HIPK3,YAF2,MBNL2,PLEKHA1,EN2,AMOTL2,AFF2,NBEA,CELF1,GABRB3,BRPF3,DHRS4,ZHX1,KLF12,NEGR1,ZIC5,MBNL1,MEST,MID1,RSPO2,NEXMIF,NCAM1,NFIA,OPCML,PCDH9,PRTG,PDE1C,PDPK1,GPR85,LRP12,EPB41L4B,RPE,LGR4,ATXN1,SCN3A,FAM19A1,SGK1,SHC4,BTBD3,SORCS3,WDTC1,SOX5,SMOC1,SSTR1,EPB41L3,SEPT3,SYT1,SYT4,CAMTA1,KLHL4,ANO4,CUX2,DICER1,EIF4ENIF1,UBE2H,UBTF,SLAIN1,BEST1,TMEM237,SMARCAD1,SYNC,NAV3,KCNAB1,SLC17A6,NETO2" MicroRNA hsa-miR-1180:mirSVR_lowEffct hsa-miR-1180:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.20E-43 6.76E-40 3.52E-43 3.25E-42 117 511 "SERPINA3,XKR4,ADD2,BRAP,AK2,LTBP4,CAPRIN2,ATP1A1,LINC00906,CACNB2,CAPN3,VSTM2A,LGI1,CHGA,PLEKHB1,KMT2C,NRXN3,PPT2,IGDCC3,SLC32A1,GDA,CSF1,RGS6,CSF2RA,ATRNL1,PLCH2,CFAP61,DOCK4,DDX46,DMD,OLIG1,DPH1,DYRK1A,EGFR,ELN,EIF1,ENO2,SEZ6,EPHB1,SRRM1,ZNF589,POLK,WDR83,APOPT1,NSG2,JPH4,RAPGEF6,SESN1,GFER,GPR17,STON1,STMN2,LINC00839,MFSD2A,GABARAPL2,AGBL5,HP,SCRT2,KCNA1,KCNA6,KCNH2,KCNK1,MBD1,MDM4,GIT1,NF1,NINJ2,NOS1,OGG1,P2RX7,PFKFB3,SEMA5B,TMIE,PLXNB3,TNPO2,CRLS1,CEP41,MAPK10,ELOVL2,SEC61A2,DGLUCY,SALL1,SCP2,PPM1E,ST3GAL3,CTXN2,RPH3A,RAB3GAP1,SCMH1,MBD5,SOX1,HECW1,ZNF423,MCF2L2,ZSCAN29,CAMTA1,EXOC7,KIAA1107,SMG6,RNF216P1,PMS2CL,SPX,AKTIP,ENHO,ASXL3,ANKRD24,ELP5,ZBTB38,POLR3H,FTSJ1,ZNF213,SYNC,MFF,DNALI1,SEMA3B,URM1,ADAMTS10" MicroRNA hsa-miR-21-5p:TargetScan hsa-miR-21-5p TargetScan 1.28E-43 7.20E-40 3.75E-43 3.46E-42 87 283 "CASKIN1,ABCD2,BCL7A,DST,KRIT1,CNOT8,HECTD1,NIPBL,CNTFR,ACBD5,PHF14,PYGO1,HDAC9,ARHGAP24,SCRN1,AIF1L,FAM107B,EDNRB,ANKRD46,HIPK3,RASGRP1,EFNA2,FAM13A,EGR3,PLEKHA1,PAN3,ARMCX1,SCML2,FOXG1,NBEA,GAB1,GLYR1,PSRC1,RFFL,KLF12,HNRNPK,NEGR1,MSL1,RBPJ,IL6R,IL6ST,IL12A,KCNA1,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,POC1B,NELL2,NFIA,OLR1,KCNK10,PDE3A,BEST3,PIK3R1,FTO,PURG,FAT3,PPP3CA,MAPK10,BCAS3,RDX,PBRM1,RPRD1A,RAVER2,ROBO2,MCMBP,AP1AR,SATB1,CSRNP3,CPEB3,FBXO11,FAM126B,PDZD2,NPAS3,C11orf87,MPRIP,FGD4,ARHGEF12,CADM1,CADM2,RGS7BP,RTN4,KAT6A,NETO2" MicroRNA hsa-miR-125b-1*:mirSVR_lowEffct hsa-miR-125b-1*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.60E-43 8.97E-40 4.67E-43 4.30E-42 100 377 "SDE2,XKR4,OLMALINC,ZNF608,FAM135A,SUGT1P4-STRA6LP-CCDC180,APP,ASCL1,SLC4A4,KIF1A,BID,SCARB1,DGKI,DIS3L,SRSF11,CASC2,FBXO7,QKI,CNR1,GREB1,RIMS2,MYEF2,COPS7A,RABGAP1L,KBTBD11,RPS6KL1,DTNA,KMT5B,SLC43A2,SRARP,STAG2,BRPF3,KIAA1841,MYOZ2,USP19,GNG4,GRIA2,LINC01551,GYG1,HAS2,CELF5,MSL1,ZNF385B,OLFM3,IPO5,PAXBP1,ARHGAP12,MEF2C,POC1B,SFR1,CNOT4,PCDH8,BEST3,PFKFB3,SSH1,RC3H2,TNPO2,MED1,KANSL1,GDPD1,CNTLN,PTPRG,KHDRBS2,RFX3,ZDHHC4,RLBP1,ZFHX4,CARF,YY1AP1,NEK11,SEMA6D,ATXN2,SCN2A,SCP2,SMPD3,NTNG1,CHD9,NLGN1,CLSTN1,ZNF430,RBM34,SPTAN1,KIF1B,ZSCAN29,SEPT3,IQCE,TBL1X,TCF4,ZEB1,NAT16,PPIL6,DCBLD1,PLEKHH2,MEAF6,SYNC,PRDM2,PARP11,UBE3B,NETO1,RNF146" MicroRNA hsa-miR-590-5p:TargetScan hsa-miR-590-5p TargetScan 1.76E-43 9.87E-40 5.14E-43 4.73E-42 87 284 "CASKIN1,ABCD2,BCL7A,DST,KRIT1,CNOT8,HECTD1,NIPBL,CNTFR,ACBD5,PHF14,PYGO1,HDAC9,ARHGAP24,SCRN1,AIF1L,FAM107B,EDNRB,ANKRD46,HIPK3,RASGRP1,EFNA2,FAM13A,EGR3,PLEKHA1,PAN3,ARMCX1,SCML2,FOXG1,NBEA,GAB1,GLYR1,PSRC1,RFFL,KLF12,HNRNPK,NEGR1,MSL1,RBPJ,IL6R,IL6ST,IL12A,KCNA1,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,POC1B,NELL2,NFIA,OLR1,KCNK10,PDE3A,BEST3,PIK3R1,FTO,PURG,FAT3,PPP3CA,MAPK10,BCAS3,RDX,PBRM1,RPRD1A,RAVER2,ROBO2,MCMBP,AP1AR,SATB1,CSRNP3,CPEB3,FBXO11,FAM126B,PDZD2,NPAS3,C11orf87,MPRIP,FGD4,ARHGEF12,CADM1,CADM2,RGS7BP,RTN4,KAT6A,NETO2" MicroRNA hsa-miR-1538:mirSVR_lowEffct hsa-miR-1538:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.00E-43 1.12E-39 5.83E-43 5.37E-42 111 464 "ASPHD1,NBAT1,ADRA1B,AP2A2,DISP3,AMPD2,PI16,PHYHD1,PPFIA3,APP,CDK10,ARNTL,ATP2B2,RGS9,BMP7,DDR1,BRSK2,HIP1R,AIFM1,ARHGEF1,CDC25B,LSMEM2,CLCN4,LY86,CCDC151,MFSD4A,ZNF385A,ARHGEF10,ERC2,PHYHIP,DAPK1,ELMO1,C2CD2L,ZNF582-AS1,DNM2,SHANK1,DPH1,ATN1,TOM1,SGK2,SUGP2,EBI3,ANKRD13B,AMOTL2,FAM49B,PRELID3A,STAU2,BRSK1,STARD10,PPARGC1A,GLS,OS9,GNAS,STON1,CECR2,ADAMTS13,GRIK5,BTN2A1,RNF165,AGBL5,ITPKA,LINC00634,KIT,CAMK2N2,LMO1,CHST6,GIT1,JAKMIP3,NUCB1,CDK18,PLIN1,PLXNB3,PPP2R5C,MAPK3,SIDT1,PSMD13,OCIAD1,RAP1GAP,ZYG11B,DUSP15,ARMC5,RPL15,TCP11L1,PTGR2,YJEFN3,FNIP1,FOXRED1,SLC11A1,SCMH1,SNRPN,FNBP1,PEG10,DBNDD2,SSTR1,ST5,SMG6,CUX2,SPX,TNFRSF1B,PIK3R5,WBP2,SMUG1,OSBP2,KLC2,SF1,UBE3B,CASC15,FAM219B,ADAMTS10,FAM198A,JPH3" MicroRNA hsa-miR-1261:PITA hsa-miR-1261:PITA_TOP PITA 2.01E-43 1.13E-39 5.88E-43 5.41E-42 79 232 "ACTN2,PWWP2A,ZNF608,ALCAM,AQP4,ZBTB10,ATP2B2,CALB1,USP6,SEPT7,CFL2,SOCS6,FRMPD4,ARMCX2,C8orf34,RHOBTB1,RAB39B,CPEB2,EGR3,EIF4G2,PLEKHA1,EML1,ERBB4,TMEM74,ETV1,EYA1,WAC,ZIC4,NBEA,AHCYL1,TOX3,PCLO,PSIP1,MIER3,GABARAPL2,NEGR1,CREG2,TTYH2,MEF2C,MEIS1,MXI1,ZC3H12B,NF1,PCDH9,SNX10,STRN3,PTPRD,PTPRZ1,RGS4,SEMA6D,SATB1,ATXN1,SCAF8,CCDC92,SEPHS1,CCDC88A,TMCC1,UNC5B,SRPK2,ITPRID2,ERBIN,SYT4,TACC1,CUX2,ARHGEF12,FRYL,TRPS1,FNDC5,USP1,NSD2,KCNK12,ZIC1,ZIC2,POLR3H,NAV3,WNK3,FZD3,KAT6A,CBLN2" MicroRNA "GTATTAT,MIR-369-3P:MSigDB" "GTATTAT,MIR-369-3P:MSigDB" MSigDB 2.29E-43 1.29E-39 6.69E-43 6.16E-42 72 190 "AP2A1,PCDH19,FAM135A,BCAS1,CASK,CDH2,NOG,NUMBL,CFL2,DNAJB5,QKI,NIPBL,KCTD8,GIT2,DNAJC6,KLHL3,PLPPR4,WDR20,DMD,YAF2,MBNL2,SEZ6,EYA1,CHST15,MEX3B,FOXG1,AFF2,FYN,GABRB3,GFRA2,GLRB,ADAMTS6,KCNJ3,MAP2,MBNL1,LRP1B,MEIS1,NPTX1,PAX6,PDE4B,PDE4D,GPR85,PPP2R2C,CEP41,PKIA,OXR1,ARID4A,RFX4,ZFHX4,ELMOD1,ST3GAL3,SLC6A1,ZNF423,CDK19,SRPK2,FBXW11,ATMIN,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,SIRT1,ZFPM2,TRPS1,VSNL1,GOPC,PIANP,ST8SIA2" MicroRNA hsa-miR-765:Functional MTI Functional MTI miRTarbase 3.35E-43 1.88E-39 9.77E-43 9.00E-42 96 350 "DPF1,CPNE2,ARID1A,ADD2,CASKIN1,SORCS2,PHF12,PRX,ARHGDIA,ARRB1,BTRC,CANX,CBS,METTL6,TMEM184B,LETMD1,CRMP1,CS,CSF1,RGS6,SLITRK5,KIAA0513,CTIF,DNM2,HEYL,CACNG7,EFNA3,EIF4G1,ING4,EPB41L1,CELF1,BRSK1,SRCAP,STARD3,GNG3,PRRC2B,GRIN2D,ZBTB45,LINGO1,HMX1,NEGR1,KCND1,KCND3,KCNH2,KIF5A,MAT2A,NBL1,NFIX,NTRK3,KSR2,PDE4A,BEST3,PFKFB3,PKM,SMIM7,PLXNB1,SPATA6,PACSIN1,POLG,POLR2F,PPP2R2B,CNNM2,TMEM231,RAB5B,IQSEC3,HES6,RPH3A,TRIM67,SOX11,SP2,UNC5B,PEG10,DBNDD2,RAP1GAP2,CAMTA2,FAM168A,ASTN2,USP22,PSD3,THRA,ZFP91,TPD52L2,TPM3,WBP2,WRN,ZNF17,ZNF70,INTS3,CIAPIN1,URM1,NAV2,ITM2C,PARP11,TMEM63C,ACTR3B,SSPN" MicroRNA hsa-miR-361-5p:PITA hsa-miR-361-5p:PITA_TOP PITA 3.54E-43 1.99E-39 1.03E-42 9.52E-42 84 266 "ADCY2,ADD3,MTUS1,DPP10,PKP4,ZBTB10,CBFA2T2,ZMYM4,MAGI1,CNOT8,KIAA1549L,ARMC8,SLC4A7,ZNF521,CREB5,CTNND1,CTNND2,RIMS3,DBT,ZNF804A,G3BP2,MTX3,EBF1,MBNL2,CALCRL,EPB41,RCAN2,GPHN,RRAGB,AFF2,FUT9,HBS1L,GLRB,GLS,GPM6A,PCLO,GRM1,GYG1,HSP90AA1,IGF1,KCNA1,KCNJ3,KIF5A,GPR155,MAP2,LRP1B,MXI1,NEXMIF,NFIX,CNTN3,PCDH9,PDE3A,PDE4B,PIK3R1,PLP1,PKIA,RELN,ZSCAN32,PLEKHB2,OXR1,LGR4,SCAF8,PPP1R9A,PPM1E,CHD9,SEC31A,RAB3GAP1,MYT1L,SOX11,STAU1,PLCB1,RPGRIP1L,PSD3,AHCYL2,ZFPM2,CSMD1,TRPS1,FLRT2,WNT7A,XRCC4,REEP1,FAM13C,ACTR3B,DPF3" MicroRNA hsa-miR-1179:PITA hsa-miR-1179:PITA_TOP PITA 3.76E-43 2.11E-39 1.10E-42 1.01E-41 82 253 "TMEM132B,CCDC85A,ADD3,SLC12A5,CDC7,RNF150,ZNF608,PCDH19,ANK1,LRCH2,ARHGAP5,ASCL1,WASF1,CACNA2D1,THSD7A,CHGB,B4GALT6,SLIT2,SLC4A7,CS,DZIP3,ERC2,APPL1,HDAC4,DNAJB6,PLEKHA1,CALCRL,TOMM40L,FGF11,KHDRBS3,GABRG2,CAB39,BRPF3,PPARGC1A,GK,GNAO1,GPM6A,RAPGEF1,GRIA2,FAM19A2,RNF165,MIER3,HMGB1,KCNA1,BLOC1S2,NEXMIF,NRCAM,GPR137C,PDYN,MED1,PTCH1,PTPRB,PTPRO,GTDC1,SYNDIG1,ATXN2,ITSN1,CPEB3,MAGI3,TET1,SNAP25,MBD5,MYT1L,CDK19,CLASP2,NKAIN2,PLCB1,CAMTA1,EHBP1,TCF4,FRYL,HHIP,SLC44A1,NR2E1,TSC1,SLAIN1,ZIC1,ZBTB38,PMEPA1,CADM2,WNK3,TMEM63C" MicroRNA hsa-miR-941:mirSVR_lowEffct hsa-miR-941:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.21E-43 2.37E-39 1.23E-42 1.13E-41 129 621 "FGD2,APBA2,FAM131A,APP,MADD,TMEM263,CAPRIN2,STX16,RIPK1,ADAM23,ADAM15,BACH1,MPDZ,HAP1,PTBP2,RGN,AIFM1,CBFA2T2,NRXN2,SLC24A2,MAP4K4,IQCK,COL4A5,COX4I1,MYRIP,HINFP,ARHGEF10,UBXN2A,GREB1,CFAP61,NOS1AP,CYBB,HDAC9,MYADM,KATNAL2,ZFYVE16,TM9SF4,HP1BP3,DNM2,FAM57B,DPP6,ECM2,KRBA2,PHC2,FCF1,TMEM132E,ELN,HSD17B14,EZH1,POLR1B,MEX3B,IP6K2,SORBS1,ZNF605,ERGIC3,GABRB1,FAM184B,FAM120B,ATP8A2,TUBGCP4,GGT7,PPARGC1A,ZNF276,PCDH11X,GNG4,DIPK1C,GRIA1,PLCD4,GRIN2D,BTN2A1,RASSF8,FRMD3,LINC01102,HMGCL,ZNF491,IL11RA,INPP5B,NME9,GATD1,KIF5C,MAP4,IL17D,MOG,MTR,OPHN1,PCSK2,ZNF655,FTO,HMGCLL1,CDIP1,CNNM2,TMEM231,ACSS3,UBR7,RGS12,RLBP1,ABCA11P,ASIC4,SH3BP2,FERMT1,MYO18A,R3HDM2,SLC9A5,MAST1,IFT122,TAB2,ZC4H2,ST5,DIP2A,KIAA1107,SIN3B,WDR7,SYNE1,OBSL1,AKNA,TNS2,ATP13A2,TIAM1,ACTR6,C9orf85,CHST5,OSBP2,FLRT2,SLC13A3,ZIC3,POLR3H,DHX33,LRP8,NUP214" MicroRNA hsa-miR-1260:mirSVR_highEffct hsa-miR-1260:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.11E-43 2.87E-39 1.49E-42 1.37E-41 130 631 "NCKAP5,BRAP,ADORA3,AK2,CDC42BPA,PARG,MIER1,CAPRIN2,ZNF582,SLC2A11,SYNJ2,PTBP2,CD86,CDH2,SOCS6,RAB28,NRXN2,COG1,HECTD1,LETMD1,MYRIP,CHD1L,RNF14,GDA,SIPA1L1,CTNND1,NRSN1,ECE2,ZFYVE16,ZNF337,TBC1D5,DBI,DBN1,HS3ST2,DMTF1,DSCAM,EPB41,EPB41L1,SEZ6,RABEPK,STX2,ZNF391,HSPA12B,FCGRT,FER,GTF2IRD2,FGFR1,SUCO,FOXF2,IQCG,SLC37A3,SORBS1,TMEM107,UFM1,NPTN,NSG1,ARPP21,IQGAP2,DISC1,NEU3,SRCAP,SULT1C4,GFAP,MSL3,ZNF638,TDRKH,LPAR4,PLCD4,GRM7,KIF3A,RASSF8,NXPH2,CFAP126,LRRC75A,IL6ST,INPP5B,ITGAV,KCNK2,KCNN3,ASPRV1,PPM1L,CD200,MSRA,NODAL,CLDN11,OXTR,PAK3,PLCL1,GRAMD1C,GON4L,BDNF-AS,RASGRF2,BSDC1,RET,RGS12,TMLHE,ROBO2,ELP2,RTKN,KCNIP1,RXRA,NCBP3,LRRTM4,FNIP1,FOXRED1,KIF21A,ITSN1,AMBRA1,ZNF365,SLC8A3,CPEB4,DBNDD2,RBM26,ADHFE1,AJAP1,NSFL1C,SYNE2,SATB2,TCF7,TPCN2,SYNE1,TNR,ZNF384,SYNPO2,AMOT,LYPD6,XKR7,PCDH15,C12orf4,RNF146" MicroRNA hsa-miR-3177:mirSVR_lowEffct hsa-miR-3177:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.03E-43 3.39E-39 1.76E-42 1.62E-41 115 502 "ABR,ASIC2,ADD2,SLC12A5,MTA3,AP2A2,GPR158,LRFN1,PPFIA2,GPAM,KIAA1614,ASTN1,NOL4,DOCK11,RGS11,GYG2,CD81,DLGAP1,ARMC8,IFFO1,HINFP,ATRNL1,DBI,PLEKHM1,COPS7A,KIAA0319,SNAP91,TMCC2,CDON,SGK2,IRAK4,ANKRD13B,SLC43A2,NCALD,ANKMY1,EYA1,FGF11,BAIAP2,SORBS1,ZMYND11,ARPP21,SEPT9,GJB1,STARD3,POLL,DCLK2,GPT2,RAPGEF1,LINC01089,FAM107A,UBE2QL1,PTGDR2,JAK1,KCNA6,KCNK1,GATD1,STMN1,NCOA7,SMAD9,SCAMP5,AFDN,N6AMT1,ZC3H12B,NTRK3,PALM,PLCB2,PLXNB3,MAPKAP1,PRKCG,MAPK4,EPDR1,PIGG,PTPRB,PTPRE,RIPOR1,RALGDS,ZYG11B,ZFHX4,TCP11L1,ABCA11P,SCP2,ASIC4,CCDC92,ZNF365,SLC20A2,ATF7IP,GKAP1,FAM219A,SP2,TEX2,TROVE2,SSTR1,EPB41L3,SSPO,CEP68,STXBP1,SYN2,KIAA1107,NEU4,RPGRIP1L,AHCYL2,CYB561A3,GPR161,THRA,TNS1,PRMT8,BCL2L13,PLPPR2,VLDLR,LMF1,NSD2,ZIC3,UPF3A,DPF3,LAS1L" MicroRNA hsa-miR-215:mirSVR_highEffct hsa-miR-215:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.23E-43 3.50E-39 1.81E-42 1.67E-41 124 579 "CSMD3,CDC7,KIDINS220,SLC24A4,ALCAM,FAM135A,LRCH2,USP28,PKP4,AMER3,ARHGAP5,PLA2G4C,CDK13,ZBTB10,ATM,CA8,VXN,RUNX1T1,ZNF501,MTMR7,CDH8,LRRFIP1,DIS3L,CASC2,NDST3,KMT2C,ZFYVE9,NIPBL,ARMC8,CLIP3,GAPVD1,ZEB2,HP1BP3,DDX46,ALKBH8,DNAH9,PHF20L1,ELAVL2,DENND4A,VPS26C,NSRP1,ZIC4,SEC23B,SEMA4D,AFF2,ATP2C1,KHDRBS3,GAD1,HBS1L,GCNT2,INSM2,GPT2,GPR22,LPAR4,PCLO,NR3C1,HNF4G,ITGAV,KCNK1,KCNN2,LIMS1,MDM4,LRP1B,MIA2,SESN3,SCG3,CTNNA3,NDUFA5,NEK1,NF1,NTRK2,NUCB2,PCDH9,MAPK4,BDNF-AS,MTMR10,PTPRZ1,RAB5B,PID1,USP47,NWD1,RIC8B,ATP8B4,ABCA11P,SCN3A,DOCK10,FBXO11,CLSTN1,ZFP1,MYH15,LIMCH1,UNC80,TRERF1,KIF21B,NKAIN2,SYNE2,PLCB1,DDHD2,ADGRL3,VWA3A,RPGRIP1L,WASHC4,PCDHGB7,PCDHB9,DICER1,LEFTY2,ZMAT3,TIAM1,C5orf64,TP53BP2,TPM1,STXBP4,FAM155A,NSD2,ZNF45,ZNF540,EML6,PLPPR5,SMARCAD1,WNK1,PCDH15,FAM47E,SLC17A6,SMIM8" MicroRNA hsa-miR-192:mirSVR_highEffct hsa-miR-192:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.23E-43 3.50E-39 1.81E-42 1.67E-41 124 579 "CSMD3,CDC7,KIDINS220,SLC24A4,ALCAM,FAM135A,LRCH2,USP28,PKP4,AMER3,ARHGAP5,PLA2G4C,CDK13,ZBTB10,ATM,CA8,VXN,RUNX1T1,ZNF501,MTMR7,CDH8,LRRFIP1,DIS3L,CASC2,NDST3,KMT2C,ZFYVE9,NIPBL,ARMC8,CLIP3,GAPVD1,ZEB2,HP1BP3,DDX46,ALKBH8,DNAH9,PHF20L1,ELAVL2,DENND4A,VPS26C,NSRP1,ZIC4,SEC23B,SEMA4D,AFF2,ATP2C1,KHDRBS3,GAD1,HBS1L,GCNT2,INSM2,GPT2,GPR22,LPAR4,PCLO,NR3C1,HNF4G,ITGAV,KCNK1,KCNN2,LIMS1,MDM4,LRP1B,MIA2,SESN3,SCG3,CTNNA3,NDUFA5,NEK1,NF1,NTRK2,NUCB2,PCDH9,MAPK4,BDNF-AS,MTMR10,PTPRZ1,RAB5B,PID1,USP47,NWD1,RIC8B,ATP8B4,ABCA11P,SCN3A,DOCK10,FBXO11,CLSTN1,ZFP1,MYH15,LIMCH1,UNC80,TRERF1,KIF21B,NKAIN2,SYNE2,PLCB1,DDHD2,ADGRL3,VWA3A,RPGRIP1L,WASHC4,PCDHGB7,PCDHB9,DICER1,LEFTY2,ZMAT3,TIAM1,C5orf64,TP53BP2,TPM1,STXBP4,FAM155A,NSD2,ZNF45,ZNF540,EML6,PLPPR5,SMARCAD1,WNK1,PCDH15,FAM47E,SLC17A6,SMIM8" MicroRNA hsa-miR-130b-3p:Functional MTI Functional MTI miRTarbase 7.14E-43 4.01E-39 2.07E-42 1.91E-41 123 571 "NCKAP5,ADAR,ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,MTMR9,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,CRY2,CSF1,UBXN2A,PPP6R2,DCAF8,DAPK1,SPATA2,FBXL5,CEP170,SEC16A,DPYSL2,EDN1,TMTC1,KMT5B,CERCAM,C3orf18,ERBB2,KATNAL1,EZH1,F3,ACSL4,DLC1,FKTN,POLR1B,SEC23B,ANKFY1,CINP,MSANTD4,SALL3,PPARGC1A,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,NR3C1,ATE1,RASSF8,IGF1,ZIC5,ZNF678,KCNB1,SFXN5,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,GPR137C,PDE3B,PDGFRA,PURG,FAT3,PPARA,KANSL1,PIGG,PXK,PTPRG,RAB5B,ZDHHC14,PTGR2,CLIP1,PPP1R9A,SYBU,BTBD3,ATF7IP,EPC1,KIF13A,SON,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,TCF4,SATB2,TCF7L2,ZEB1,TRIM2,DICER1,GPR161,ZMAT3,SLC44A1,THRA,NACC2,RGMB,TRPC3,UBC,SLAIN1,TOM1L2,VLDLR,ZNF711,ZNF24,ZNF154,MFF,LRP8,WIPF2,WNK3,GOPC,FXR1,SOCS4" MicroRNA hsa-miR-370:mirSVR_highEffct hsa-miR-370:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.88E-43 4.43E-39 2.29E-42 2.11E-41 125 589 "TTYH1,ADD3,NLGN4X,CASKIN1,KCTD16,RTL9,ALAD,USP35,PCDH10,ANK3,CNTNAP1,DGKZ,SEMA4G,PPP4R4,PDXK,SLC4A4,N4BP2L1,ADGRB2,DNAJC27-AS1,BID,ARHGEF7,CDC25B,MAGI1,BTF3L4,BAG4,CSF2RA,PDE4DIP,UBXN2A,PHF14,DOCK4,HDAC4,PABPC5,EXOG,USP3,ATL1,EFNB3,PHF20L1,SUGP2,MRO,EPHA5,EPHB1,GPHN,MRPL37,FCGR1A,FDFT1,FER,FGF11,WDR83,ZCCHC17,UFM1,OGA,CAB39,ARPP21,GAP43,GLYR1,ADAMTS13,RASSF8,HPS5,SMAP1,ZNF678,JAK2,KCNJ11,PIK3AP1,MBNL1,MDM4,XRRA1,SCG3,RTL5,NCAM1,NF1,NME4,PBX1,DPY19L2P2,HERC2P3,ZNF655,A2ML1,FAM216A,FXYD1,EXOSC10,ING3,SEPT4,PPM1B,PRKACB,SIDT1,PSMD13,PTPRB,ZSCAN2,RAP1GDS1,DBX2,CARF,EPHA10,UEVLD,ATP8B4,ATAT1,ATXN2,SCP2,ASIC4,SH3GL3,PPM1E,AMBRA1,CDK5RAP2,SMARCD3,MBD5,TAB2,SS18,SULF2,STXBP1,AJAP1,FNDC9,DDHD2,SZT2,AP4E1,AKTIP,BHLHB9,TPM2,DCBLD1,LRTM2,AMOT,CCDC136,TOM1L2,MAP3K12,PRTFDC1,PRDM10,ZNF248,RNF170" MicroRNA "CTTTGCA,MIR-527:MSigDB" "CTTTGCA,MIR-527:MSigDB" MSigDB 7.89E-43 4.43E-39 2.29E-42 2.11E-41 76 217 "ADD2,KLHL13,DPP10,API5,CDK13,CACNA1E,HAP1,CAMK2A,PRC1,DCLK1,LGI1,PUM1,SV2A,SRGAP3,DSCAM,FAM78B,MBNL2,KMT5B,EGR3,PAN3,EPB41L1,NCALD,ACSL4,PTK2B,NBEA,ZCCHC17,NSG1,STAG2,GGT7,TNRC6A,RNF165,SOX21,KLF12,IDH3A,KCNMA1,MBNL1,MEF2C,MYCN,NOVA1,OCRL,OGDH,PAX6,GPR85,PFKFB4,PLEC,EPB41L4B,PPP2R5E,PBRM1,ZNF532,ROBO1,KCNIP2,SALL1,SEMA6D,ATXN1,CHD9,FNDC3A,WDR47,CPEB4,SOX11,KIF1B,RAP1GAP2,NFASC,SRPK2,VPS13A,PLCB1,ATP11A,TACC1,ANKRD12,TBX15,SATB2,TCF12,ZFPM2,ZIC1,PMEPA1,PIANP,SENP7" MicroRNA hsa-miR-525-3p:mirSVR_lowEffct hsa-miR-525-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.97E-43 4.48E-39 2.31E-42 2.13E-41 106 430 "DGCR6,EMILIN3,ADD3,ESYT2,PCDH19,LRRC7,PDZD4,PITPNM2,AMPD2,ANK3,SEMA7A,CDC14B,SNAI3-AS1,NAE1,CACNB2,CACNB4,NGB,VXN,CCKBR,SCARB1,CHGA,CHRM1,IGLON5,CST3,PPP1R16B,ERC2,ARHGAP32,TOX,ZNF337,TBC1D5,LIN54,ARMCX4,PITPNC1,C8orf34,MAGI2,SRGAP3,WDR20,SLC29A4,HIPK3,NRN1,TOMM40L,SUCO,SEMA6C,SEMA4D,PDLIM5,FAM49B,B3GAT1,ILDR2,AHCYL1,ZNF274,IP6K3,EML4,GRB10,GRID1,LINC00839,ZBTB49,ADAMTS6,PADI2,LINC00667,KCNJ10,KIF5A,PAXBP1,MN1,BLOC1S2,MXI1,HNRNPM,CDK18,ANLN,FAM216A,PLCB2,PLIN1,PLXNB3,SDK2,PPP1R1A,PPP2R5C,MAPK4,CNTLN,ZIK1,SLC25A48,PRRT2,CCDC82,KLHDC8A,ROBO1,PRR5L,TCP11L1,RYR3,ARX,URGCP,SEPHS1,SLC11A1,SORCS3,INAVA,KDM4B,ZSWIM8,SSTR1,MPRIP,AJAP1,MLST8,SATB2,ZFPM2,TPM2,TRO,WIPF1,EML6,HNRNPA3,CPNE4" MicroRNA "AAGCAAT,MIR-137:MSigDB" "AAGCAAT,MIR-137:MSigDB" MSigDB 8.45E-43 4.75E-39 2.45E-42 2.26E-41 74 205 "ABHD6,CSMD2,FMNL2,OGT,CADPS,ASPH,STX16,ARHGEF7,CACNA1G,BSN,CDC42,QKI,ZNF385A,RIMS4,ST18,RIMS3,RHOBTB1,SRGAP3,DYRK1A,RBM12,SLC43A2,ERBB4,ZMYND11,C15orf41,PPARGC1A,ATOH8,WIF1,KLF12,BACH2,HLF,SCRT2,KCNA2,MEIS2,MITF,MMP16,MSI1,MYBPC1,NEUROD1,NOVA1,GPR88,PDE4A,PLEC,MED1,PPP3CB,PPP5C,SNRK,NKAIN1,OXR1,MORC4,RFX4,RAVER2,RORB,SATB1,PPM1E,FNDC3A,ST3GAL3,SHANK2,LIMCH1,SON,SOX11,NFASC,PLCB1,SYT1,ANKRD12,RPGRIP1L,THBS4,RELL2,UBE2H,FLRT2,MGAT5B,SPHK2,SYNC,SLC17A6,CBLN2" MicroRNA hsa-miR-204-5p:Functional MTI Functional MTI miRTarbase 8.64E-43 4.85E-39 2.50E-42 2.31E-41 102 399 "AS3MT,XKR4,ADCY5,ADCYAP1R1,ADORA3,MTA3,SORCS2,AK2,SPOP,CACHD1,SEMA4G,ARSE,ASGR1,ATP2B1,BCL2L2,BCL7A,BID,MYRF,LURAP1,CAMK2G,SYT6,CDC42,CDH2,CDH8,SLC22A6,DNAJB5,SEC31B,CREB5,CHD5,PLCXD3,CYBB,ELMSAN1,G3BP2,CHRDL1,FEM1B,SLC43A2,SRARP,AMOTL2,FOXM1,ANKFY1,FAXC,SRCAP,RAB40B,TPPP,NR3C1,PTPRT,HAS2,PADI2,GPR45,BACH2,MIER3,HMX1,HSP90AA1,EID2B,JAK2,LSAMP,MBNL1,MDFI,MEIS1,MEIS2,XRRA1,SAMD5,MX1,NPTX1,NTRK2,PHKG1,KANSL1,MARCH1,RAB5B,CEP97,USP47,ZYG11B,DPF2,GTDC1,RORB,ELP2,TMEM156,ATXN1,ATXN7,ASIC4,GALNT10,MYO18A,BCAN,LRRC55,ZCCHC24,CLUAP1,ZBTB43,SMOC1,LRRC4,IQCE,TCF4,TCF7L2,TCF12,SIRT1,SEZ6L,TMEFF2,PRDM2,CSDE1,WNK3,ZDHHC20,DPF3,GAN" MicroRNA hsa-miR-140-5p:PITA hsa-miR-140-5p:PITA_TOP PITA 1.09E-42 6.11E-39 3.15E-42 2.90E-41 86 283 "SYS1,CSMD3,GALNT16,ADCY6,ZNF608,OSBPL6,OGT,DPP10,ZBTB10,NCOA1,CADM3,BCL2L2,WASF1,FOXN3,CNOT8,CNR1,CNTN1,RBM39,CSNK1G3,ERC2,HDAC4,SCRN1,DLG2,DMTF1,DPYSL2,RBM12,EIF4G2,ELAVL2,EPB41L2,ERBB4,ANKFY1,CELF1,NCKAP1,SRCAP,PPARGC1A,GK,TCERG1,PCDH11X,GPM6A,ADAMTS6,CYP27C1,TTYH2,MARK1,MPP2,PABPC1L2A,NEUROD2,NFE2L2,NFYA,ZNF827,PDGFRA,GPR85,CDK14,STRN3,DRAM2,PROX1,WBP1L,TMEM260,RIC8B,NUDT11,PBRM1,RTN1,SEMA6D,ELMOD1,SUPT20H,HSPA4L,FAM102A,SH3GL2,SOX11,MYCBP2,ERBIN,ST5,SATB2,DICER1,HEY1,TJP1,RIMBP2,R3HDM1,FNDC5,SLAIN1,FLRT2,ZIC3,POLR3H,NAV3,SNX27,WNK2,FXR1" MicroRNA hsa-miR-671-5p:mirSVR_highEffct hsa-miR-671-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-42 6.66E-39 3.44E-42 3.16E-41 126 600 "ESYT2,PTCHD1,KCTD16,CCDC146,PHF12,APC,GPAM,DST,CASTOR3,CAPN3,VXN,CBS,LDB2,CCKBR,AIFM1,C1orf52,LOC730101,CFL2,SYNPR,EPS15L1,ARMC8,SUMF2,MYRIP,HS3ST5,FAM171B,CRY2,SEC24C,ATRNL1,RIMS2,DAPK3,HP1BP3,SACS,SV2A,KBTBD11,EDN1,PHC2,ANKRD46,SGK2,EGFR,KMT5B,NRN1,DLC1,RACK1,SORBS1,PDLIM5,CELF1,MSANTD4,DKK3,FAM120B,DISC1,ADGRA3,GPM6A,GPM6B,MCHR1,GRIN1,CLASRP,MFSD2A,HPS5,HMGCL,HNMT,HPCA,HSD17B1,IGSF1,KCNJ10,KCNK1,KIT,KLC1,CAMK2N2,ASPRV1,MAN2A2,MAOB,MARK1,SYT9,LRP1B,SHC3,MOBP,OMG,PCSK1,SERPINE2,SSH1,ST8SIA5,PLXNB1,EPB41L4B,PPP2R5C,GRAMD1C,SIDT1,CNTLN,PTPRD,CASTOR1,ZSCAN2,RAD52,FAT4,SEC61A2,ROBO2,ATP8B4,LRRK2,ATXN7,IL17RB,GALNT10,ARX,R3HDM2,PAAF1,WDR37,SEPT3,WSCD1,SATB2,SYNE1,USP32P1,CYB561A3,DDHD1,PIK3R5,TTPA,HEPACAM,RPL7L1,VSNL1,SF1,PCDH20,ZNF189,FTSJ1,PLPPR5,STOX2,HPS4,FZD3,NLRP3,TIGD6,FRMD6" MicroRNA hsa-miR-4265:mirSVR_highEffct hsa-miR-4265:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-42 7.09E-39 3.66E-42 3.37E-41 108 448 "CLK4,CSMD3,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,ALS2,VAT1L,AQP6,ATP2B1,LDHD,CACNA1D,CACNB2,RUNX1T1,CLDN10,CERS5,AIFM1,L3MBTL4,COPB2,RAB33A,COG1,CNR1,NCOR1,SNCAIP,CSF1R,PDE4DIP,ST18,DOCK4,HDAC4,BRINP1,PLEKHM1,CEP170,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,SLC37A3,ARFGAP2,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,GPD2,GRIA1,HPS5,PADI2,ZNF546,KCNC2,GPR62,KCNJ4,KCNJ16,KCNN3,PAXBP1,MAOB,MDM4,MEIS2,LAYN,NME4,CAMKV,CRLS1,WBP1L,CNTLN,RAD52,VEPH1,RGS3,RGS4,CSRNP3,SLC1A7,SLC8A3,ATF7IP,TET1,ZSWIM8,ENKUR,KDM4C,LMO3,TAB2,VPS13A,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,FAM13C,RNF146,SPATA13" MicroRNA hsa-miR-214:PITA hsa-miR-214:PITA_TOP PITA 1.46E-42 8.20E-39 4.22E-42 3.89E-41 91 319 "KCNH8,ACLY,UNC5A,INTS2,SEMA6A,MARK4,CHRD,CACNA1I,BSN,LURAP1,FOXN3,NRXN3,QKI,PICK1,COL4A5,TBPL1,MYRIP,IGDCC3,SEC24C,SOCS5,RIMS4,PUM1,RUBCN,KIAA0513,RIMS3,JAKMIP2,MYEF2,SRGAP3,DNAJB6,FAM135B,PHC2,YAF2,EIF4G1,TAOK3,ATP8A1,FHL1,AGAP2,AFF2,FAM49B,BRPF3,NCKAP1,SESN1,AHDC1,PCLO,GRIN1,GRM7,ZIC5,MAP2,CHIC1,MITF,MOV10,GPR85,PLXNB3,RETREG2,KANSL1,TMEM260,PID1,OXR1,DUSP15,SETD5,SPIN3,SALL1,SEMA6D,SCN3A,SCP2,CPEB3,MYO18A,CNKSR2,ANKRD6,ABLIM3,SLC8A1,CPEB4,WDTC1,MYT1L,SOX11,PEG10,MMS19,CAMTA1,DMXL2,SZT2,DOCK9,TRPS1,FNDC5,CADM1,FAM155A,UBE2H,KLC2,ZIC1,SYNC,PPP1R3F,HNRNPA3" MicroRNA hsa-miR-33b*:mirSVR_highEffct hsa-miR-33b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-42 1.26E-38 6.49E-42 5.97E-41 123 577 "CLK4,NCKAP5,ADCY6,KIAA1324,SMIM17,ARHGAP20,OGT,ANK3,EP400,PPFIA1,ATP1A2,ADAM23,SGCE,CA4,CACNA1D,RCBTB2,COG1,TPP1,IQCK,ARMC8,AKAP6,CLOCK,CS,PDE4DIP,CFAP61,USP6NL,DOCK4,HDAC9,GAPVD1,SPOCK2,BRINP1,ARMCX4,ZNF804A,SNAP91,DLG2,NR1D2,ABI1,PDCD6IP,DNM1L,PHF20L1,MRNIP,RGS17,DCTN4,EPB41,SRRM1,WAC,FGFR1,SUCO,HPCAL4,TMEM107,UFM1,STAG2,KIAA1841,RND1,RAB30,GLS,FAM19A2,LINC01551,SOX21,PSIP1,HSPA1L,HSP90AA1,HTR5A,ZNF678,KCNC1,KCNC2,LMO2,MAT2A,MATN3,MBD1,ZNF680,ZNF92,MYO6,NCAM1,SFR1,NF1,NUMA1,PRTG,MTRF1L,RETREG2,PPP3CA,BDNF-AS,PXK,PTPRB,PTPRG,FAT4,RAP1GAP,RASGRF2,SLC6A15,ZYG11B,ZFHX4,CYB561D1,NEK11,RTKN,CSRNP3,HSPA4L,ITSN1,NTNG1,NUBPL,DHX30,CMTR2,USP33,BDP1,ITPRID2,SSTR1,RGL1,KANK1,SYT1,ANKRD28,MCF2L,TCF12,SYNE1,DOCK9,HHIP,NPL,ANKRD20A2,TSC1,WIPF1,SMARCAD1,DHX33,DNALI1,LINC02210,UBE3B" MicroRNA hsa-miR-4296:mirSVR_highEffct hsa-miR-4296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.51E-42 1.41E-38 7.26E-42 6.69E-41 107 443 "CLK4,CSMD3,UNC5A,PTCHD1,AGT,KIAA1324,ZNF687,AMT,FGD2,APC,ALS2,VAT1L,AQP6,ATP2B1,LDHD,CACNA1D,CACNB2,RUNX1T1,CLDN10,AIFM1,L3MBTL4,COPB2,RAB33A,COG1,CNR1,NCOR1,SNCAIP,PDE4DIP,ST18,DOCK4,HDAC4,BRINP1,PLEKHM1,CEP170,RHOBTB1,SPOCK3,EXOG,USP3,DMTF1,EDNRA,TUBD1,FAM198B,CEP78,PPP1R1B,OLFM1,POLK,SLC37A3,ARFGAP2,ZNF605,ABLIM2,MEGF10,TMEM8B,ADAM28,PCDH17,MALT1,BRD8,ZNF276,TNRC6A,MSL3,LOXL3,GRIA1,HPS5,PADI2,ZNF546,KCNC2,GPR62,KCNJ4,KCNJ16,KCNN3,PAXBP1,MAOB,MDM4,MEIS2,LAYN,NME4,CAMKV,CRLS1,WBP1L,CNTLN,RAD52,VEPH1,RGS3,RGS4,CSRNP3,WDR37,SLC1A7,SLC8A3,ATF7IP,TET1,ZSWIM8,ENKUR,KDM4C,LMO3,TAB2,VPS13A,TCF4,OBSL1,TNS2,TIAM1,R3HDM1,PLEKHH2,LGI4,ZSCAN26,FAM13C,RNF146,FAM198A,SPATA13" MicroRNA "GGGACCA,MIR-133B:MSigDB" "GGGACCA,MIR-133B:MSigDB" MSigDB 2.65E-42 1.49E-38 7.66E-42 7.05E-41 71 190 "ASIC2,SLC25A25,OSBPL8,CNTNAP1,ARHGDIA,PCDHGB4,DDX3Y,BACH1,ADGRB1,BCL2L2,NIPA1,CDK5R2,PTBP2,USP6,ARHGEF2,CDC42,CLTC,ZNF385A,SOCS5,KIAA0040,GAPVD1,IP6K1,ELMSAN1,DNM2,DNAJB6,TNK2,ACSL4,FOXG1,RAPGEF6,TTBK1,GRM5,ATOH8,AGBL5,IL6ST,KCNH2,NNAT,NPTX1,NUMA1,PCDHGC3,PFKFB3,ZDHHC8,SEMA5B,RETREG1,CDIP1,PRRX1,PACSIN1,PRRT2,SCN2B,SLC8A3,SOX11,MYCBP2,NFASC,STX1A,GANAB,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ZFP91,USP32P2,CELF4" MicroRNA "GGGACCA,MIR-133A:MSigDB" "GGGACCA,MIR-133A:MSigDB" MSigDB 2.65E-42 1.49E-38 7.66E-42 7.05E-41 71 190 "ASIC2,SLC25A25,OSBPL8,CNTNAP1,ARHGDIA,PCDHGB4,DDX3Y,BACH1,ADGRB1,BCL2L2,NIPA1,CDK5R2,PTBP2,USP6,ARHGEF2,CDC42,CLTC,ZNF385A,SOCS5,KIAA0040,GAPVD1,IP6K1,ELMSAN1,DNM2,DNAJB6,TNK2,ACSL4,FOXG1,RAPGEF6,TTBK1,GRM5,ATOH8,AGBL5,IL6ST,KCNH2,NNAT,NPTX1,NUMA1,PCDHGC3,PFKFB3,ZDHHC8,SEMA5B,RETREG1,CDIP1,PRRX1,PACSIN1,PRRT2,SCN2B,SLC8A3,SOX11,MYCBP2,NFASC,STX1A,GANAB,TRIM2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,ZFP91,USP32P2,CELF4" MicroRNA hsa-miR-1224-3p:mirSVR_highEffct hsa-miR-1224-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-42 1.55E-38 7.97E-42 7.34E-41 111 476 "NCKAP5,NDRG2,CCDC85A,BRAP,CDC7,PDZD4,CDC42BPA,UPRT,VAT1L,MIER1,ADAM23,SYNJ2,PTBP2,CAMK2G,CD86,PLEKHB1,DGCR9,HECTD1,MYRIP,CHD1L,SEC24C,SIPA1L1,ZFYVE16,ZNF337,TBC1D5,SPOCK2,PLEKHM1,RUSC2,HS3ST2,DMTF1,ABI1,ABI2,EPB41,ZNF391,SPEG,PRMT5,SUCO,ANKFY1,TMEM107,ST6GALNAC3,GABRA3,TRAF3IP2,ARPP21,SULT1C4,GFAP,MSL3,TDRKH,CLASRP,ADAMTS6,HNRNPK,USP51,LRRC75A,IL6ST,IL12A,LRRTM3,ITGA7,KCNK2,KCNN3,KIF5A,L1CAM,CAMK2N2,MIA2,CD200,ZNF92,NDUFA5,NODAL,GLIPR1L2,PDE1A,PLCL1,SEPT4,CCDC144B,PRKACB,GRAMD1C,BDNF-AS,STRC,RGS12,TMLHE,ELP2,ABCA11P,LINC00461,FNIP1,TNFRSF19,ASIC4,FOXRED1,ZNF365,RUFY2,SLC8A3,SPHKAP,SMARCC2,MYT1L,DBNDD2,RBM26,LARP4,TTBK2,ADHFE1,NSFL1C,SYNE2,PLCB1,CAMTA1,EHBP1,NAT16,RBFOX2,TMPRSS5,CADM1,SLC35A4,ZNF708,TRIM9,LYPD6,VPS35L,SLC17A6,ZNF30" MicroRNA hsa-miR-550:mirSVR_highEffct hsa-miR-550:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.82E-42 1.59E-38 8.14E-42 7.49E-41 124 587 "ABCF1,ADCY2,ADD2,SORCS1,BEND6,RTL9,OSBPL8,FAM135A,IGDCC4,ARHGAP5,CDK13,ATM,ATP1A2,BCL2L2,CACNA1E,CACNB2,SPAG9,CCNH,MTMR7,CD86,LGI1,DLGAP1,CASC2,PPT2,NGEF,TJP2,ARMC8,AKAP5,AHCTF1,SNCAIP,CX3CR1,DOCK4,DGKB,DAPK1,BRINP1,GIT2,B3GAT3,SV2A,CCDC3,DLX1,PDCD6IP,DYRK1A,YAF2,ELAVL2,RGS17,EMX2,EPHA5,GPHN,WAC,FGF1,SCARA3,STAU2,TBR1,AP4B1,DOT1L,TRAF3IP2,CAB39,INPP5K,GART,RND1,RAB30,GLS,KCNMB4,RAPGEF4,GRIK3,TMEM25,PSIP1,ADAMTS6,IGSF21,C1orf94,TLX1,HTR5A,USP54,IL6ST,KCNJ9,KCNN2,ASPRV1,MAP4,MAT2A,LRP1B,PPM1L,CTNNA3,NCAM1,PDGFRA,NLGN3,TMEM38A,PCDH18,PLXNB3,SCHIP1,FSD1,PPP2R5E,EPDR1,DIRAS2,GON4L,STK32A,FAM66C,GTDC1,PTGR2,ST6GALNAC6,FAM182A,HOGA1,TRIM46,MAGI3,SLITRK3,SLC8A3,RCOR3,RIMS1,ERBIN,ADGRL3,KLHL4,ACSL6,MTMR14,TNR,TPM1,NPL,SYNPO2,TSC1,CADM1,RPL7L1,TRIM9,EML6,LINC00632,NUP214,RNF170" MicroRNA hsa-miR-744*:mirSVR_highEffct hsa-miR-744*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.91E-42 1.64E-38 8.40E-42 7.73E-41 125 596 "KLHL32,ALCAM,PCDH10,MRTFA,AMPH,PPFIA1,SHTN1,ARNTL,CDK13,SYNJ1,KALRN,PTBP2,TRIM41,CAST,CERS5,CD86,LRRFIP1,LOC730101,NDST3,COG1,DNAJB5,AKAP7,ARMC8,RBM39,CSNK1G3,NRSN1,BOC,HDAC9,GPRASP1,TOX,MATR3,DAPK1,ZEB2,DMD,DOCK2,DNM1L,EDN3,GPHN,IGSF6,ZNF391,FABP7,OLFM1,BAIAP2,FOXG1,RASL10A,NPTN,MEGF10,GAD1,C15orf41,DISC1,PPARGC1A,TXNL4A,CRCP,RNPS1,SPIN1,KCNMB4,WDFY3-AS2,GPM6B,CCDC184,STON1,GRIA4,GRM7,PTPN5,VSIG4,HPCA,LRRC75A,IL6ST,LIMS1,MEF2C,ERICH3,GPR173,A2ML1,SNX10,ING3,SPATA6,SAMD9,MDGA2,EML5,CEP97,SLC25A48,DBX2,ZMAT4,ZFHX4,SUGCT,RORB,WLS,SAFB,SEMA6D,FAM19A1,SCP2,HSPA4L,PPM1E,FNDC3A,SLC1A3,RUFY2,NAPB,RCOR3,RIMS1,SNRPN,UNC80,SON,TRERF1,SP4,CAND2,NKAIN2,SS18,TBX15,CRB1,THRA,ERCC6L2,TMOD1,TRO,TMEFF2,RPL7L1,NPDC1,FTSJ1,WNK1,FIP1L1,FAM47E,PARP11,DOCK8,CASC15,ADAMTSL3,SNX14,SSPN" MicroRNA hsa-miR-92b*:mirSVR_lowEffct hsa-miR-92b*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.09E-42 1.74E-38 8.91E-42 8.21E-41 108 452 "ABHD6,GPRIN1,ADD1,ADORA1,UNC5A,SNX32,AK2,MRTFA,DOC2A,PITPNM2,AMPD3,PKP4,BCAS1,CPNE5,ASPH,ADGRB2,DST,CACNA1D,P2RX6,SYNGR3,EVI5L,JAM2,TMEM59L,WHRN,CABP1,NCOR2,MICAL2,ATRNL1,ERC2,ARHGAP32,ARHGAP24,PLEKHM1,SMG7,CHRDL1,TRAPPC9,DNM2,ARRDC4,PHF20L1,MTSS1L,FCGR1A,FCGR1B,EVL,SEMA4D,ARFGAP2,DISC1,GRM1,CLASRP,IL1RAPL1,GSTT2,SLC2A6,HRH3,ATXN2L,MIER3,GABARAPL2,SHISA6,FAM95B1,KCNMA1,LRRC4B,FXYD7,NEUROD2,NKX2-2,CLEC9A,ZDHHC22,PFKFB3,TMIE,SLC25A23,PLTP,PILRA,PACSIN1,FA2H,PTPA,PRKCG,ELOVL2,PYGM,ZNF493,RASGRF1,ZDHHC14,KIRREL1,PCMTD2,MCMBP,FAM192A,ATXN2,SHMT2,BCAN,ST3GAL3,CLSTN1,ARFGAP1,ZSWIM8,TSPYL2,ATP10B,SYP,KAZN,MTCL1,CAMTA1,CNTN2,TBL1X,TCF7L2,RPGRIP1L,SLC19A3,OBSL1,ZFPM2,GALNT17,KCTD2,CSMD1,TMPRSS5,RPRM,VIPR2,PLPP4" MicroRNA hsa-miR-302f:PITA hsa-miR-302f:PITA_TOP PITA 3.39E-42 1.90E-38 9.75E-42 8.98E-41 84 273 "CSMD2,FMNL2,DSCAML1,SLITRK1,ERMN,USP31,HECW2,OSBPL1A,ALCAM,ANK3,ALS2,DDX3Y,STX16,BCL7A,DST,CACNA1E,THSD7A,CAMK2G,LRBA,CFL2,FOXN3,SLC4A7,KIAA0408,FRMPD4,HDAC4,RIMS3,MAGI2,DYNC1I1,ABI1,SUGP2,TENM1,RGS17,AGAP2,SGIP1,C15orf41,AHDC1,TOX3,ADAMTS6,KLF12,NEGR1,SCRT2,KIF5A,PACRG,MYH7,ZC3H12B,NEUROD1,NPTX1,PDE4D,GPR85,GNG2,ZFYVE21,ST8SIA5,PLEC,MAPKAP1,PPP2R2B,SNRK,PTPRZ1,PID1,TTLL7,ROBO2,SATB1,ATXN7,LRRTM4,NLGN1,SLC1A2,SLC6A1,RCOR3,PDZRN3,SOX5,SP2,SRPK2,NECAB1,PRRC2C,ADGRL3,HEY2,KAT6B,NR2C2,UBE2H,CLDND1,SPHK2,SYNC,WNK1,GOPC,CBLN2" MicroRNA hsa-miR-1915*:mirSVR_highEffct hsa-miR-1915*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.75E-42 2.11E-38 1.08E-41 9.93E-41 109 461 "EMILIN3,ADD2,SORCS1,KIAA1211,CCDC146,LCORL,PPFIA1,SHTN1,RGS20,ARSF,BRINP2,CALB2,USP6,CHN1,ZFYVE9,KIAA1549L,HECTD1,CPS1,RBM39,ANKRD44,GDA,ATRNL1,DOCK4,ZFYVE16,DAPK1,IP6K1,HS3ST4,USP3,DTNB,AASDH,WDPCP,TMEM74,EXTL2,RACK1,FGF11,SLC37A3,PDLIM5,GAP43,DISC1,MSL3,LOXL3,GPD1,GRIA2,ADAMTS6,TLX1,USP51,EID2B,IDH3B,IGF1,ZNF678,KCNJ9,KCNN2,KLC1,FGFBP3,MAN2A2,ADAM22,MSR1,HS6ST3,MXI1,SLCO1C1,NNAT,NODAL,CNOT4,LOC100128398,ZNF827,ZDHHC22,ZNF655,PRRX1,MED1,WDR25,ACSS3,ENOX1,RASGRF2,MSANTD2,RLBP1,RNASEL,SETD5,KLHDC8A,ATAT1,FAM19A1,FHOD3,CNKSR2,PAAF1,SMARCE1,ANKRD36,ZNF415,USP33,KIF1B,MCF2L2,NFASC,NKAIN2,ADHFE1,SYT4,CAMTA1,ADGRL3,TCF7,AZIN2,FAM200B,PMS2CL,C18orf54,CHST5,METTL3,ZNF28,PCDH15,MVB12B,UBE3B,TIGD6,MSRB3,IFT88" MicroRNA hsa-miR-193b:mirSVR_highEffct hsa-miR-193b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.93E-42 2.21E-38 1.13E-41 1.04E-40 104 421 "KCTD16,RTL9,HACE1,ALCAM,UPRT,STX16,BTRC,CALB1,THSD7A,CALM1,SPAG9,RUNX1T1,USP6,CDH8,PLAA,TPP1,COL4A5,MICAL2,CTNND2,EARS2,ZC3H11A,WDR20,E2F6,EPHA5,RABEPK,CAP2,HVCN1,ST6GALNAC3,CAB39,RAPGEF6,DISC1,GART,ARFIP1,PPARGC1A,RAB30,GNAO1,PSRC1,ADAMTS13,AGBL5,ZNF181,KCNC2,LAMP2,STMN1,LIMS1,MBD1,MRPL42,MSRA,CTNNA3,MYCN,NF1,NOVA1,GPR137C,PBX1,PDCD2,PDE1A,PPP2R5C,CEP41,MAPK10,DEF8,CNTLN,FAT4,MSANTD2,MORC4,SEC61A2,CARF,GLDN,LRRK2,SCP2,ELMO2,SLC20A2,SNRPN,SON,SPATA7,BDP1,SP4,ERBIN,ST5,SULF2,SEPT3,SLC37A2,C12orf76,CAMTA1,AGTPBP1,DMXL2,TCF7L2,RPGRIP1L,ARHGEF12,USP32P1,R3HDM1,SMUG1,ZMYND8,RUSC1,CADM1,PITPNB,PLEKHH2,CCDC14,ZIC3,LINC02210,LINC00632,NELFE,ADAMTSL3,ZNF248,IFT88,RNF146" MicroRNA hsa-miR-380*:mirSVR_highEffct hsa-miR-380*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.11E-42 2.31E-38 1.18E-41 1.09E-40 97 367 "ACHE,NBAT1,KIAA1211,PTCHD1,KLHL13,KCTD16,C1QTNF3,PHF12,ASCL1,CAPRIN2,ASPH,ASTN1,EIF4G3,BACH1,NRP2,CAMK2D,ISPD,CDC27,GDA,MICAL2,OSBPL3,CSNK1G3,PNPLA8,GRIN3A,ECM2,FAM135B,ELAVL4,EPB41L1,CLVS1,EFEMP1,TESK2,FGF13,POLK,FAM49B,GABRA2,ZMYND11,IGSF5,TCERG1,RAB30,ZNF782,GPM6B,PLCD4,GRIK2,SERP2,GRM1,TLX1,TCEAL6,SMAP1,GAREM2,ITGAV,CREG2,SYTL4,NRBP2,NCF2,SLC11A2,HCN1,NUCB2,ZNF713,PPM1B,PRKACB,MDGA2,CNTLN,DBX2,FIGN,NUDT11,PBRM1,PNMA8A,ATP8B4,LGR4,RTN1,SCN8A,LRRC55,ZNF334,SLC15A2,SLC20A2,SORCS3,ANKRD36,SNRPN,UNC80,KIF21B,NPAS3,STOX1,CEP68,FGD4,SYPL1,VWC2,WDR7,CADM1,UBE3A,CLDND1,GUSBP1,PLPPR5,MFF,KCNAB1,FIP1L1,WNK3,SSPN" MicroRNA hsa-miR-127-5p:PITA hsa-miR-127-5p:PITA_TOP PITA 5.83E-42 3.27E-38 1.67E-41 1.54E-40 80 248 "ACLY,SLITRK1,ADRB2,KLHL13,DDX3Y,STX16,CADM3,CAMK2G,TRIM41,SRSF11,FOXN3,CNR1,ARMC8,GAPVD1,ARHGAP24,ZEB2,G3BP2,DMD,CASP8AP2,DRD1,HIPK3,EFNA3,GPR61,MBNL2,ELAVL2,ENPP6,ETV1,SGIP1,FUT9,OGA,PCDH17,PPARGC1A,RND1,MAP7D2,LOXL3,WIF1,INSM1,KIF5C,MAN2A2,MEIS2,NCAM1,NCAM2,NEFM,NEK1,NEUROD1,CAMKV,PIK3R1,POLG,NXPH1,KANSL1,TMEM104,PTCH1,UHRF1BP1,OCIAD1,OXR1,GTDC1,RGS7,SATB1,CPEB3,DOCK10,SLC8A1,RCOR3,SP4,LHFPL4,TAB2,POGZ,RGL1,C3orf70,ANKRD28,TAC1,CAMSAP2,TCF7,RPGRIP1L,ZFPM2,AMOT,CADM2,RGS7BP,HNRNPA3,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-708:mirSVR_highEffct hsa-miR-708:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.95E-42 3.34E-38 1.71E-41 1.57E-40 141 747 "SDE2,ACADM,ACHE,AS3MT,RNF150,SLC44A5,HACE1,BEGAIN,AMPH,ZFAT,OGT,PPFIA1,PKP4,SEMA4G,ASPA,CACNA1G,C5,PTBP2,CAMK2D,CAST,CLDN10,CD38,ARHGEF2,ZBED1,CDH18,SRSF11,TJP2,CNTFR,CLOCK,PREPL,GDA,SNCAIP,OSBPL3,SUSD5,NCAN,FAM169A,DOCK4,GAPVD1,TMEM170A,GIT2,DCT,C8orf34,MED24,SMG7,SV2B,NTM,DYRK1A,ABCC5,YAF2,EN2,EPHA5,F8,FABP7,CEP78,FGF1,NELFCD,NSG1,AP4B1,GABRA1,GAD2,NEU3,GNG4,GPM6A,PLCD4,GSTT2,GUCY1A2,MAEL,ATXN2L,IGFBP1,KIF5A,MAT2A,LYRM9,MYO9A,FXYD6,NELL1,SLCO1C1,NFE2L2,DNHD1,NTRK3,NUMA1,OLR1,ZNF827,PBX1,SERPINE2,ZNF655,HMGCLL1,MTRF1L,PRKCZ,SAMD9,GON4L,MDGA2,TMEM260,ZIK1,C1orf109,ZNF615,MARCH1,MSANTD2,RDX,NUDT11,RPRD1A,GSTCD,YY1AP1,LRRK2,SCN3A,CASC3,ITSN1,SEC31A,EPN2,PKNOX2,SIRT2,SHANK2,MAST1,SMARCE1,SNAP25,MYO16,TTBK2,RGL1,ADHFE1,DMXL2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,TIE1,TMEM9,TMPO,R3HDM1,ELP5,CCDC14,SLC13A3,ETNPPL,DHX33,PRDM2,PCDH15,PDSS2,KAT6A,JMJD1C" MicroRNA hsa-miR-105*:mirSVR_lowEffct hsa-miR-105*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.87E-42 4.42E-38 2.26E-41 2.08E-40 114 506 "KDM5D,ELFN2,SPOP,AMPD2,APLP1,ASPH,GPR146,CFLAR,BMPR1B,ARHGEF7,CALB1,CAST,BRSK2,CD38,ARHGEF2,CDC42,LRRFIP1,CLTA,NIPBL,ABI3BP,NRG2,CREM,CSNK1G3,CYBB,KATNAL2,LIN54,DAPK1,SCRN1,DDX46,ALKBH8,NTM,DPH1,DPP6,ABCC5,EDNRB,MBNL2,ELAVL3,EIF1,KCNMB2,SRARP,WAC,FCGR1B,HRASLS5,FAM184B,TUBGCP4,SRCAP,ARFIP1,GFER,RAPGEF4,GRM2,GYG1,PACSIN2,KCNK1,KCNN2,SMAD1,MAOB,SHC3,ERICH3,ADAM22,NEK1,OMG,PDE1A,PIRT,PDPK1,PLXNB3,PDZRN4,PMP22,PPARA,GRAMD1C,DEF8,TMEM260,PTPRB,PTPRE,RIC8B,CARF,ROBO2,ACER3,MAP6D1,RXRA,SATB1,ATXN2,CHD9,R3HDM2,NLGN1,KDM4D,NAPB,ANKRD36,WDTC1,FNBP1,ZNF423,NPAS3,GSE1,SYN1,MLST8,ADGRL3,MGRN1,TBX15,EHBP1,WASHC4,WDR7,ARHGEF12,ERCC6L2,TSN,SGK3,FAM155A,UGT8,CCDC14,GUSBP1,ZNF23,MKRN3,EML6,ADAMTS9,URM1,NUP214" MicroRNA hsa-miR-212-5p:TargetScan hsa-miR-212-5p TargetScan 1.04E-41 5.85E-38 2.99E-41 2.75E-40 91 326 "PITPNM2,PKP4,KIAA1614,DDX3Y,BCL2L2,BID,LDHD,LDLRAD4,CACNA1E,DDR1,CALM1,CDC27,CFL2,NIPBL,NRG2,CSNK1E,PPP1R16B,APPL1,MAML1,DLG3,CALN1,RCAN1,HEYL,EGR3,MRVI1,GABBR1,GABRA5,ALDH1L1,RAB30,KDM2B,GPM6B,PLCD4,GRIK3,GRIN1,KAT7,MFSD2A,ATOH8,BACH2,HNF4G,MSL1,RBPJ,LRRTM3,KCNB1,KCNC2,LSAMP,MARK3,MAT2A,MEIS1,GIT1,C10orf105,MXI1,NFIA,IGSF11,OPHN1,GPR137C,PIRT,GNG2,FTO,CDIP1,PRRX1,PROX1,RALGDS,ROBO2,RIMKLA,HUNK,AMER2,DRAXIN,ATXN7,PRCD,FAM81A,LRRC55,FAM126B,IQSEC2,RAP1GAP2,CLASP2,POGZ,LARP4,COBL,CNTN2,FBXW11,NSD1,ARHGEF12,NACC2,CBX5,FNDC5,OSBP2,LYPD6,GDPD5,PIANP,CBLN2,GAN" MicroRNA hsa-miR-1226:mirSVR_highEffct hsa-miR-1226:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-41 5.92E-38 3.02E-41 2.78E-40 125 603 "KCNH8,ACADM,AP2A2,CC2D2A,CEP126,OGT,PPFIA1,SUGT1P4-STRA6LP-CCDC180,PKP4,MARCH3,TTLL9,ADAM15,CAMK2G,CAST,CCKBR,TMEM257,CLCN3,QKI,LETMD1,MFSD4A,LRIG1,APPL1,KATNAL2,DCAF8,TM9SF4,ARMCX4,ZEB2,DDX46,SV2B,WDR20,DNM1,ABI1,MAMLD1,ABCC5,KLHL5,PHF20L1,ELAVL3,DCTN4,FCGR1A,TESK2,KAT8,IP6K2,NOP56,UFM1,ARFGAP2,CELF1,CGREF1,SALL3,NEU3,GLI2,EML4,GRIA2,GRIA4,FAM19A2,ADAMTS6,ACOT7,GABARAPL2,IL11RA,INPP5B,KCNK2,CREG2,SYTL4,MAP4,MAT2A,MBD1,MOG,NCAM1,NDUFA5,NODAL,DNHD1,HCN1,NTRK3,ETFRF1,PCSK5,GNG2,MED1,PRKCG,PRKCZ,PTPRE,RAD51D,ATG16L1,NWD1,ROGDI,RASGRF2,RDX,GAL3ST4,CARF,ROBO1,ELP2,RPL15,FBXW7,GLDN,SCN8A,SFPQ,ITSN1,SH3GL2,NTNG1,FBXO11,ST3GAL3,NUBPL,SLC8A1,NAPB,CPEB4,NAXD,ABTB1,RIMS1,PALLD,SOX5,BDP1,NPAS3,LMO3,ITPRID2,ADHFE1,PRRC2C,OBSL1,AP4E1,TIAM1,AMACR,UGT8,ZIC1,TRIM9,ZNF154,ZSCAN26,SYNC,KAT6A" MicroRNA hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA_TOP PITA 1.25E-41 7.00E-38 3.57E-41 3.29E-40 87 298 "KCNH8,ADD3,PLEKHH1,INTS2,KCTD16,HACE1,TAOK1,BCAR3,ARHGAP20,CNIH2,ZBTB10,NOL4,FUBP1,BTRC,ARHGEF2,REPS2,DCLK1,CFL2,QKI,KLHL3,G3BP2,ATL1,SH3GLB1,ELAVL2,ERBB4,MED12L,PSD2,TACC2,HVCN1,FUT9,OGA,PHYHIPL,IQGAP2,LPAR4,EML4,GPR37,ZHX1,KLF12,KTN1,MBNL1,MEIS2,NAP1L1,NEUROD1,NFIA,NOVA1,PDE4B,PDGFRA,SERPINE2,PLP1,FAT3,NXPH1,PPP2R5E,ZSCAN32,FAM120C,PTPRZ1,RORB,ZC3H14,ELMOD1,PPP1R9A,NTNG1,SLC1A2,WDR47,CCDC88A,SLC20A2,CPEB4,SMARCC2,KDM3A,TAB2,STAU1,PLCB1,SYPL1,TACC1,FBXW11,ZEB1,ARHGEF12,DDHD1,RIMBP2,SGK3,VLDLR,CLDND1,SLC38A1,TMEM178A,NAV3,MVB12B,ADAMTSL3,FXR1,DPF3" MicroRNA hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA_TOP PITA 1.25E-41 7.00E-38 3.57E-41 3.29E-40 87 298 "KCNH8,ADD3,PLEKHH1,INTS2,KCTD16,HACE1,TAOK1,BCAR3,ARHGAP20,CNIH2,ZBTB10,NOL4,FUBP1,BTRC,ARHGEF2,REPS2,DCLK1,CFL2,QKI,KLHL3,G3BP2,ATL1,SH3GLB1,ELAVL2,ERBB4,MED12L,PSD2,TACC2,HVCN1,FUT9,OGA,PHYHIPL,IQGAP2,LPAR4,EML4,GPR37,ZHX1,KLF12,KTN1,MBNL1,MEIS2,NAP1L1,NEUROD1,NFIA,NOVA1,PDE4B,PDGFRA,SERPINE2,PLP1,FAT3,NXPH1,PPP2R5E,ZSCAN32,FAM120C,PTPRZ1,RORB,ZC3H14,ELMOD1,PPP1R9A,NTNG1,SLC1A2,WDR47,CCDC88A,SLC20A2,CPEB4,SMARCC2,KDM3A,TAB2,STAU1,PLCB1,SYPL1,TACC1,FBXW11,ZEB1,ARHGEF12,DDHD1,RIMBP2,SGK3,VLDLR,CLDND1,SLC38A1,TMEM178A,NAV3,MVB12B,ADAMTSL3,FXR1,DPF3" MicroRNA hsa-miR-526b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-41 7.06E-38 3.60E-41 3.31E-40 129 640 "ADAR,FMNL2,FZD9,SORCS2,ZNF578,KIF6,SEMA7A,CAPRIN2,ATP1B3,MTMR9,BCL2L2,LDHD,NIPA1,FOXK1,MAP7,ZBED1,DIS3L,CFL2,EPS15L1,ZFYVE9,QKI,BTF3L4,ZNF385A,CPS1,ENTPD4,SOCS5,UBXN2A,DCAF8,KIAA0513,DNAL1,YTHDC1,PLEKHM1,FBXL5,CEP170,RABGAP1L,SLC12A6,DPYSL2,DNAJB6,FEM1B,SH3GLB1,KMT5B,ABI2,IRAK4,ELAVL2,CERCAM,BSCL2,TLR7,KATNAL1,F3,WAC,ACSL4,GTF2IRD2,POLR1B,SUCO,TPK1,TRAF3IP2,SALL3,C15orf41,KIAA1841,FAXC,SRCAP,SESN1,CRCP,CBX1,LUZP2,FUT10,NR3C1,MFSD2A,FICD,HAS2,HMGB1,KCNB1,KCND3,ARHGAP12,GPR155,SESN3,NBL1,CNOT4,PDPK1,PFKFB2,PFKP,ZFYVE21,TMEM38A,ZNF426,LRP12,PRKACB,PRKCB,SLC22A23,PXK,OCIAD1,RAB5B,CEP97,ZNF532,TMEM100,ATAT1,FOXRED2,ATXN1,DRAXIN,TMEM200C,HSPA4L,RUFY2,FAM126B,SON,SP2,SP4,EMC1,SMOC1,STAC2,WWC1,TCF7L2,GPRIN3,ZMAT3,NACC2,CBX5,PARD3,TPM4,RGMB,NR2C2,UBC,ZNF70,EMSY,CADM2,CSDE1,WIPF2,MPPE1,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 1.38E-41 7.74E-38 3.94E-41 3.63E-40 79 244 "CPNE2,C3orf14,KCTD16,PCDH10,ANK1,ANK3,ANXA7,IGDCC4,DOCK11,BCL2L2,MTMR3,BSN,BTRC,CAMK2B,CAMK2G,LRRFIP1,DLGAP2,NCOR2,RIMS2,HDAC4,GPR61,ELAVL2,ELAVL3,MTSS1L,EPHA5,CEP85L,FLT1,ANKFY1,CHL1,GABRB1,LYVE1,RNF165,IL1RAPL1,BACH2,HNRNPK,ATCAY,IGSF1,KCNA6,KPNA5,INSYN2,SAMD14,NFIX,CNOT4,HCN1,PDE4A,PURG,MED1,MDGA2,ELOVL2,DPF2,FIGN,KCTD17,RPRD1A,RORB,MCMBP,CSRNP3,ATXN2,ATXN7,SCN3A,ITSN1,CCDC88A,MAPKBP1,MBD5,MYT1L,LHFPL4,NPAS3,NFASC,CLASP2,ANKRD12,ARHGEF12,CBX5,CSMD1,KAT6B,NR2C2,CADM1,FLRT2,KLC2,POLR3H,CADM2" MicroRNA hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 1.38E-41 7.74E-38 3.94E-41 3.63E-40 79 244 "CPNE2,C3orf14,KCTD16,PCDH10,ANK1,ANK3,ANXA7,IGDCC4,DOCK11,BCL2L2,MTMR3,BSN,BTRC,CAMK2B,CAMK2G,LRRFIP1,DLGAP2,NCOR2,RIMS2,HDAC4,GPR61,ELAVL2,ELAVL3,MTSS1L,EPHA5,CEP85L,FLT1,ANKFY1,CHL1,GABRB1,LYVE1,RNF165,IL1RAPL1,BACH2,HNRNPK,ATCAY,IGSF1,KCNA6,KPNA5,INSYN2,SAMD14,NFIX,CNOT4,HCN1,PDE4A,PURG,MED1,MDGA2,ELOVL2,DPF2,FIGN,KCTD17,RPRD1A,RORB,MCMBP,CSRNP3,ATXN2,ATXN7,SCN3A,ITSN1,CCDC88A,MAPKBP1,MBD5,MYT1L,LHFPL4,NPAS3,NFASC,CLASP2,ANKRD12,ARHGEF12,CBX5,CSMD1,KAT6B,NR2C2,CADM1,FLRT2,KLC2,POLR3H,CADM2" MicroRNA hsa-miR-186-5p:Functional MTI Functional MTI miRTarbase 1.54E-41 8.63E-38 4.39E-41 4.05E-40 141 753 "TTYH1,SDE2,RBM10,CC2D2A,PCDH10,TRMT9B,KIF6,APC,ARRB1,ATP1B3,ATP2A2,ZNF583,LDHD,CDK5R1,ST3GAL5,FOXK1,CAMK2B,CBR1,LRRFIP1,SRSF11,KMT2C,BTF3L4,AHCTF1,ZNF385A,AKAP12,RIMS4,PUM1,MATR3,RIMS3,DBN1,FBXL5,BLOC1S6,MTX3,DLG3,FEM1B,EEF1D,FRY,GOLGA7,EIF4G2,EIF5,EIF1,VPS13B,MTSS1L,DNAJC27,KATNAL1,NSRP1,ACSL4,DLC1,RACK1,SEC24B,POLR1B,UBE2E3,FOXM1,SPECC1,MSANTD4,STAG2,MTHFD2,SEPT9,USP19,MSL3,GLUL,CBX1,GRIK5,GUCY1B1,MIER3,HSP90AA1,ZIC5,RBPJ,TUBB2B,ITPKB,METTL21A,KIT,SMAD1,MAT2A,MRPL42,CCDC80,NASP,CNOT4,P2RX7,ABCB1,KCTD15,ZNF426,PURG,PSAT1,RETREG2,TNPO2,PPM1B,PRKAB2,VPS13C,QRICH1,PSMD13,PIGG,BDNF-AS,PTPN13,ZNF793,RALGDS,BEND5,ERI2,FIGN,RGR,ACER3,WLS,FAM192A,FOXRED2,ATXN1,FNIP1,KIF21A,SHMT2,AMBRA1,RAB3GAP1,SMARCC2,SON,BDP1,PEG10,SEPT8,SIN3B,ZFP90,TRIM2,NSD1,TEX15,TGFBR3,HHIP,SLC44A1,ZFP91,RBFOX2,RPL7L1,PLEKHH2,SF1,PLPP4,AMZ1,DPYSL5,PROCA1,SPIRE1,WNK1,SLC30A4,MFF,CSDE1,STOX2,PAK5,PHTF2,RNF146" MicroRNA hsa-miR-582-3p:PITA hsa-miR-582-3p:PITA_TOP PITA 1.79E-41 1.01E-37 5.12E-41 4.72E-40 81 258 "ADCY2,RTL9,OSBPL8,ARHGAP5,ASCL1,DCAF5,JAZF1,BTRC,CACNB4,SEPT7,CDH10,ZMYM4,NOG,FOXN3,SYNPR,FAM19A5,CREB5,CTNND2,LONRF1,AIF1L,LYPD1,DPH1,FAM13A,ELAVL3,ATP8A1,CAMSAP1,FOXO3,DACH2,TBR1,BRPF3,PCDH17,TNRC6A,FERMT2,PCLO,CIT,GYG1,MIER3,KIF5C,MAP2,MAPT,MAT2A,NCAM1,PCSK2,PDE4D,PDYN,CDK14,CAMKV,PDZRN4,TTC13,ENOX1,RDX,PBRM1,SPIN3,SCN2A,PPP1R9A,CHD9,NLGN1,SLC6A1,TMCC1,ZCCHC24,NPAS3,CLASP2,RGL1,TBL1X,EHBP1,TCF4,PUM2,FRYL,FBXL16,R3HDM1,TPM4,ZNF384,TRPS1,TSN,WIPF1,KCNT2,SMARCAD1,CA10,CSDE1,NAV3,KAT6A" MicroRNA hsa-miR-185:PITA hsa-miR-185:PITA_TOP PITA 1.96E-41 1.10E-37 5.61E-41 5.17E-40 73 207 "ASIC1,ARID1A,PTCHD1,PCDH19,APP,ARHGAP5,ATP1A3,CARMIL3,ADGRB1,BSN,THSD7A,DGKI,CDC42,LHX2,ZNF385A,CSNK1G3,DGKB,HP1BP3,C2CD2L,KLHL3,SMG7,DLG2,GPR61,ELAVL3,EIF1,RCAN2,AGAP3,NPTN,GAP43,CPLX1,TOX3,TNRC6A,RFFL,KAT7,FAM222A,AGFG1,SCRT2,LRRTM1,KCNN3,KLC1,MAP2,MAP4,MAT2A,MEIS1,MSI1,RTL5,PABPC1L2A,NEUROD2,NFIX,PBX1,PCDH9,CCSER2,FAM184A,SETD5,LRFN5,SMARCC2,SNAP25,FAM219A,SOX5,NMNAT2,HECW1,STAC2,TCF12,THRA,TJP1,SSBP2,NSD2,SF1,REEP1,SLC30A3,CA10,PAK5,KAT6A" MicroRNA hsa-miR-874-3p:TargetScan hsa-miR-874-3p TargetScan 2.31E-41 1.30E-37 6.59E-41 6.07E-40 78 239 "DSCAML1,GRAMD1B,PTCHD1,BEND6,DYNLL1,BCL7A,MTMR3,MYRF,CACNA1E,CACNB2,RUNX1T1,FMNL3,PCYT1B,COL9A2,HAPLN1,CNTNAP2,GREB1,PPP6R2,FRMPD4,IST1,RHOBTB1,EGR3,ELAVL3,PPP1R1B,MED12L,FGF1,DCTN2,ATP2C1,CPLX2,HEPN1,CRCP,GLDC,FICD,RNFT2,IGFBPL1,MBD1,MOG,MXI1,MYO9A,NRCAM,PAK3,PAX6,PBX1,GNG2,PRRX1,POU3F2,PPP5C,PSD,BCAS3,PIGG,PLEKHB2,ATG16L1,RGS4,CYB561D1,ATXN1,CNKSR2,PAAF1,CPEB4,EPC1,LHPP,CLSTN2,AJAP1,EXOC7,SATB2,PSD3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,NR2C2,BCL2L13,RBFOX3,GDPD5,HNRNPA3,MSRB3" MicroRNA hsa-miR-362-3p:TargetScan hsa-miR-362-3p TargetScan 2.48E-41 1.39E-37 7.07E-41 6.52E-40 81 259 "RNF157,PPFIA4,GAS7,NCOA1,BCL7A,BAIAP3,FOXK1,PTBP2,KRIT1,CCNT1,NUMBL,PLAA,IGDCC3,CRMP1,CSNK1G3,CHD5,CTNND1,MYADM,MATR3,DAPK1,CHRDL1,DPYSL2,HIPK3,EIF4G1,MTSS1L,CHST15,ANKFY1,NCKAP1,FAXC,PRUNE2,RNF165,MFSD2A,DDX19B,KLF12,HP,HPR,MSL1,IL6ST,KIF2A,KIF5A,IPO5,L1CAM,MGAT3,OPCML,PCSK2,PDE3A,PDE4D,PFKFB2,OLA1,FAT3,PRKACB,FITM2,CNNM2,PTPRG,C12orf49,RPE,PTGR2,SBF1,CSRNP3,ATXN1,BTBD3,CPEB4,MBD5,PEG10,FAM168A,ATP11A,MLST8,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HHIP,ASXL3,DOK6,RGMB,CADM1,DPYSL5,PMEPA1" MicroRNA hsa-miR-329-3p:TargetScan hsa-miR-329-3p TargetScan 2.48E-41 1.39E-37 7.07E-41 6.52E-40 81 259 "RNF157,PPFIA4,GAS7,NCOA1,BCL7A,BAIAP3,FOXK1,PTBP2,KRIT1,CCNT1,NUMBL,PLAA,IGDCC3,CRMP1,CSNK1G3,CHD5,CTNND1,MYADM,MATR3,DAPK1,CHRDL1,DPYSL2,HIPK3,EIF4G1,MTSS1L,CHST15,ANKFY1,NCKAP1,FAXC,PRUNE2,RNF165,MFSD2A,DDX19B,KLF12,HP,HPR,MSL1,IL6ST,KIF2A,KIF5A,IPO5,L1CAM,MGAT3,OPCML,PCSK2,PDE3A,PDE4D,PFKFB2,OLA1,FAT3,PRKACB,FITM2,CNNM2,PTPRG,C12orf49,RPE,PTGR2,SBF1,CSRNP3,ATXN1,BTBD3,CPEB4,MBD5,PEG10,FAM168A,ATP11A,MLST8,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,HHIP,ASXL3,DOK6,RGMB,CADM1,DPYSL5,PMEPA1" MicroRNA hsa-miR-193a-3p:mirSVR_highEffct hsa-miR-193a-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.63E-41 1.48E-37 7.48E-41 6.89E-40 109 470 "KCTD16,RTL9,HACE1,ALCAM,UPRT,STX16,BTRC,CALB1,THSD7A,CALM1,SPAG9,RUNX1T1,USP6,CDH8,PLAA,TPP1,COL4A5,MICAL2,CTNND2,EARS2,GIT2,ZC3H11A,E2F6,IRAK4,EPHA5,RABEPK,CAP2,HVCN1,ST6GALNAC3,CAB39,RAPGEF6,DISC1,GART,ARFIP1,PPARGC1A,RAB30,CBX1,GNAO1,PSRC1,GPR12,ADAMTS13,AGBL5,ZNF181,KCNC2,LAMP2,STMN1,LIMS1,MRPL42,MSRA,SCG3,MYCN,NF1,NOVA1,GPR137C,PBX1,PDCD2,PDE1A,MED1,PPP2R5C,CEP41,MAPK10,DEF8,CNTLN,FAT4,MSANTD2,MORC4,CARF,GLDN,LRRK2,SCP2,SCG5,CCDC88A,ELMO2,SLC20A2,SNRPN,SON,SPATA7,BDP1,SP4,ERBIN,ST5,SULF2,SEPT3,SLC37A2,C12orf76,CAMTA1,AGTPBP1,DMXL2,TCF7L2,RPGRIP1L,ARHGEF12,USP32P1,R3HDM1,C9orf85,SMUG1,ZMYND8,RUSC1,CADM1,PITPNB,PLEKHH2,CCDC14,ZIC3,LINC02210,LINC00632,NELFE,ADAMTSL3,ZNF248,IFT88,RNF146" MicroRNA hsa-miR-4283:mirSVR_highEffct hsa-miR-4283:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.92E-41 1.64E-37 8.31E-41 7.65E-40 94 352 "TTYH1,ASPHD1,ASIC2,ACHE,BRAP,MTUS1,CC2D2A,USP35,AMPD2,OGT,FGD2,LCORL,DGKZ,MADD,ADAM15,CASTOR3,KALRN,RUNX1T1,ENTPD6,DGKI,KMT2C,ANKRD44,CLIP3,CSNK1E,VAC14-AS1,EARS2,DLG2,DNM1,SLC25A18,EBF1,FCF1,EGFR,F5,CACNG3,SPSB4,IP6K2,FLT1,TMEM8B,SIGLEC8,STARD10,LRRC37A6P,AHDC1,TNRC6A,GLUL,GNG3,GPD2,CECR2,HPCA,CFAP126,ITPKB,MATN2,SYT9,MEIS2,ERICH3,MX1,FXYD6,DNHD1,PBX1,PDE2A,PLXNB1,PILRA,PSD,PTAFR,MSANTD2,FIGN,CARF,NEK11,ST6GALNAC6,TRIM46,ASAP3,ANKRD36,SNCB,SNRPN,MYO16,KIF1B,NFASC,SEPT3,FGD4,SYN1,SYT1,TAL1,RNF216P1,DICER1-AS1,FBXL16,MTMR14,ZNF384,TRPC3,OSBP2,WIPF1,SF1,PCBP1-AS1,SMIM8,CASC15,MSRB3" MicroRNA hsa-miR-650:PITA hsa-miR-650:PITA_TOP PITA 3.05E-41 1.71E-37 8.68E-41 8.00E-40 71 196 "SDE2,ASIC1,NCOA1,KIF1A,SYNJ1,CAMK2G,DLGAP2,CHN2,CPNE6,QKI,PICK1,LETMD1,MYRIP,FAM171B,CREB5,NCOR2,CSNK1G3,RIMS4,CTNND1,SNPH,KLHL3,CELSR3,EGR3,CORO2B,PSD2,OGA,JPH4,GPR162,PCLO,GRIN2D,RNF165,CELF3,ZIC5,IBA57,KCNA1,MITF,NRGN,ZNF827,PBX1,PRTG,PDE1B,PIK3R1,CCSER2,PMP22,RETREG2,RIPOR1,RAB5B,RGS7,CYB561D1,ROBO1,SCP2,FAM102A,FAM214B,WDTC1,KIF21B,SOX11,NCDN,FBXW11,TCF4,AHCYL2,SLC44A1,HEY1,CBX5,R3HDM1,DOK6,NR2C2,TRPC3,KCNE5,UBE3A,PAK5,PIANP" MicroRNA hsa-miR-193a-5p:mirSVR_highEffct hsa-miR-193a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.31E-41 2.98E-37 1.51E-40 1.39E-39 115 524 "KCNH8,ADCY2,DSCAML1,PCDH10,ZNF687,ALS2,RGS20,NUMB,SEC11C,RGS11,BMPR1B,CASTOR3,JAZF1,CACNA1G,KALRN,RUNX1T1,NFS1,DCLK1,ZMYM4,EPS15L1,SLC4A8,CLIP3,CSF1,CSNK1G3,PHACTR3,GREB1,HDAC9,FRMPD4,RHOBTB1,NR1D2,CPEB2,ABCC5,USH1C,PHF20L1,CALCRL,KCNMB2,ERBB2,RCSD1,FGF11,NOP56,DKK3,DISC1,PCDH11X,ZNF638,CBX1,GPM6B,GRM1,ZNF496,RNFT2,MSL1,LRRTM3,OLFM3,KCNN2,SYT9,MDM4,ADAM22,NOVA1,NUCB2,ZNF827,PDE1C,OLA1,CAMKV,FAM218A,HMGCLL1,C19orf57,POU3F2,PROX1,MASP1,RELN,MDGA2,ZSCAN32,PTPRN2,ZSCAN2,ZNF844,RBBP6,HKR1,CARF,RORB,RPE,ABCA11P,LINC00461,ITSN1,SLC22A4,COA1,TTC17,SSPO,SULF2,GANAB,PLCB1,ANO4,ZFP90,RALYL,PCDHAC2,USP32P1,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ASXL3,TMPO,ZNF384,PRMT8,ELP5,TTC3,RPL7L1,GORASP1,UGT8,LMF1,MKRN3,FAM13C,TRAM2-AS1,NETO2,SLC4A10" MicroRNA hsa-miR-501-3p:mirSVR_highEffct hsa-miR-501-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.21E-41 4.05E-37 2.05E-40 1.89E-39 106 450 "ACTN1,KIAA1324,OGT,APAF1,GPAM,USP37,ASPH,BCL7A,DST,JAZF1,CACNB2,PTBP2,SLC25A14,CDC27,ZMYM4,RCHY1,RNF14,CFAP61,DCAF8,DAPK1,SIRPA,ZEB2,CCDC3,NR1D2,DRD1,DNAJB6,KCTD3,ELAVL2,F3,FCGR1A,UBE2E3,AGAP3,ATP13A4,NBEA,ATP6V1H,STAU2,AHCYL1,ARPP21,DISC1,MSTN,GLI2,PCDH11X,TDRKH,PCLO,GRIA2,CIT,CYP27C1,MBD1,TM6SF1,AFDN,JAKMIP3,MYCN,NEFM,NF1,OGDH,CLDN11,PCDH9,PCSK5,PDE3B,GDAP1L1,PMP22,CCDC144B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,PRKCZ,MAPK9,BDNF-AS,PTHLH,ACSM5,SLC6A15,ZFHX4,RPL15,ATP8B4,SATB1,SCN2A,SGK1,NTNG1,SLITRK3,ST3GAL3,SEPHS1,EPC1,RCOR3,TRERF1,HECW1,KDM4C,PEG10,ZBTB43,NPAS3,SEPT8,PRRC2C,ATP11A,DDHD2,ITGB3BP,HEY1,DDHD1,CADM1,UBE2H,KCNT2,EML6,ZNF189,CSDE1,AMN1,GAN,LAS1L" MicroRNA "TACTTGA,MIR-26A:MSigDB" "TACTTGA,MIR-26A:MSigDB" MSigDB 7.43E-41 4.18E-37 2.11E-40 1.94E-39 84 283 "PLEKHH1,SLC24A4,ZNF608,AMPH,EP400,APC,ALS2,USP37,SHTN1,ATM,ATP1A2,SLC4A4,NOL4,KALRN,TMEM184B,AKAP6,SLC4A7,ACBD5,CTNND2,DAPK1,SPOCK2,PITPNC1,C2CD2L,POM121,SACS,G3BP2,USP3,EIF4G2,EIF5,PAN3,CAMSAP1,MEX3B,GABRB3,NEK6,TNRC6A,ADAMTS6,HTR2A,IGF1,KCNK1,SMAD1,MAP2,MARK1,MITF,MMP16,CD200,BLOC1S2,MXI1,PCDH9,PDGFRA,PFKFB3,PLP1,PCDH18,FA2H,SH3KBP1,PPP3CB,SLC22A23,PTPN13,TTC13,RGS4,ZFHX4,RPS6KA2,LGR4,RTN1,SALL1,MRAS,FBXO11,SLC12A2,BTBD7,TMCC1,ZCCHC24,CLASP2,EPB41L3,LARP4,STAC2,VAMP1,PLCB1,PSD3,TRPC3,AMOT,VLDLR,CLDND1,WNK3,PHTF2,VANGL2" MicroRNA "ACATTCC,MIR-206:MSigDB" "ACATTCC,MIR-206:MSigDB" MSigDB 7.43E-41 4.18E-37 2.11E-40 1.94E-39 84 283 "SLC25A25,ADAR,MRTFA,OGT,MAP4K3,DGKZ,BCL7A,SYNJ2,BSN,CDC42,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREM,CREB5,AKAP12,RIMS4,HDAC4,MATR3,DGKG,PLPPR4,DLG4,DMPK,E2F5,EDN1,PHC2,CELSR3,BSCL2,RCAN2,ZIC4,FGF14,IP6K2,SLC37A3,PDLIM5,CPLX2,KDM2B,ADGRA3,GPD2,TPPP,RNF165,BACH2,HMGCR,HNRNPK,SMAP1,IGF1,KTN1,MEIS1,GIT1,ZNF827,TMOD2,CDK14,GDAP1L1,TNPO2,MED1,WBP1L,PTPRG,BSDC1,RIT2,PBRM1,FBXW7,SEMA6D,TRA2B,FNDC3A,SLC8A2,SMARCA4,SNAP25,MAPKBP1,TMCC1,USP33,SP2,SS18,TRIM2,PSD3,PUM2,TGFBR3,SLC44A1,LRRC8A,TPM3,UBE2H,TBC1D15,RICTOR" MicroRNA "TACTTGA,MIR-26B:MSigDB" "TACTTGA,MIR-26B:MSigDB" MSigDB 7.43E-41 4.18E-37 2.11E-40 1.94E-39 84 283 "PLEKHH1,SLC24A4,ZNF608,AMPH,EP400,APC,ALS2,USP37,SHTN1,ATM,ATP1A2,SLC4A4,NOL4,KALRN,TMEM184B,AKAP6,SLC4A7,ACBD5,CTNND2,DAPK1,SPOCK2,PITPNC1,C2CD2L,POM121,SACS,G3BP2,USP3,EIF4G2,EIF5,PAN3,CAMSAP1,MEX3B,GABRB3,NEK6,TNRC6A,ADAMTS6,HTR2A,IGF1,KCNK1,SMAD1,MAP2,MARK1,MITF,MMP16,CD200,BLOC1S2,MXI1,PCDH9,PDGFRA,PFKFB3,PLP1,PCDH18,FA2H,SH3KBP1,PPP3CB,SLC22A23,PTPN13,TTC13,RGS4,ZFHX4,RPS6KA2,LGR4,RTN1,SALL1,MRAS,FBXO11,SLC12A2,BTBD7,TMCC1,ZCCHC24,CLASP2,EPB41L3,LARP4,STAC2,VAMP1,PLCB1,PSD3,TRPC3,AMOT,VLDLR,CLDND1,WNK3,PHTF2,VANGL2" MicroRNA "ACATTCC,MIR-1:MSigDB" "ACATTCC,MIR-1:MSigDB" MSigDB 7.43E-41 4.18E-37 2.11E-40 1.94E-39 84 283 "SLC25A25,ADAR,MRTFA,OGT,MAP4K3,DGKZ,BCL7A,SYNJ2,BSN,CDC42,CLCN3,CLTC,QKI,CNN3,BAG4,SLC35F1,CREM,CREB5,AKAP12,RIMS4,HDAC4,MATR3,DGKG,PLPPR4,DLG4,DMPK,E2F5,EDN1,PHC2,CELSR3,BSCL2,RCAN2,ZIC4,FGF14,IP6K2,SLC37A3,PDLIM5,CPLX2,KDM2B,ADGRA3,GPD2,TPPP,RNF165,BACH2,HMGCR,HNRNPK,SMAP1,IGF1,KTN1,MEIS1,GIT1,ZNF827,TMOD2,CDK14,GDAP1L1,TNPO2,MED1,WBP1L,PTPRG,BSDC1,RIT2,PBRM1,FBXW7,SEMA6D,TRA2B,FNDC3A,SLC8A2,SMARCA4,SNAP25,MAPKBP1,TMCC1,USP33,SP2,SS18,TRIM2,PSD3,PUM2,TGFBR3,SLC44A1,LRRC8A,TPM3,UBE2H,TBC1D15,RICTOR" MicroRNA hsa-miR-670-3p:TargetScan hsa-miR-670-3p TargetScan 7.54E-41 4.23E-37 2.14E-40 1.97E-39 100 402 "ABHD6,C3orf14,NDRG3,ADORA2A,KIF6,ANK3,PKP4,APBB2,MARCH3,MARK4,NCOA1,DCAF5,CAMK2D,FMNL3,CCNT1,MAGI1,CCPG1,NRXN3,NRXN2,FHL5,RTTN,IPCEF1,SDC3,APPL1,CYBB,ARHGAP24,HDAC4,HEYL,DENND4A,NSRP1,PDLIM5,NPTN,MSANTD4,NRG3,GHDC,HIGD1B,ERAP1,KIAA1958,OS9,GPR12,PTPRT,IL1RAPL1,KAT7,LINGO1,CELF3,RASSF8,HMGB1,HNRNPK,RBPJ,IL6ST,LRRTM3,ITGA7,KCND3,KCNK1,KCNN3,KCNQ3,NCOA7,MBNL1,MDM4,MOG,NFIA,ENPP2,PRRX1,FAT3,PRKACB,CEP41,CNNM2,APTX,PXK,PEX2,RAP1GDS1,REV3L,PBRM1,RNASEL,C12orf49,ALG9,RORB,AMER2,CSRNP3,DZIP1,FAIM2,FAM126B,BDP1,ELOVL4,FAM168A,C3orf70,CNTN2,KIAA0930,AHCYL2,FBXL16,CBX5,RBFOX2,RUNDC3B,AMOT,LRP8,RTN4,HNRNPA3,RSPRY1,FXR1,GAN" MicroRNA hsa-miR-15a-5p:Functional MTI Functional MTI miRTarbase 9.50E-41 5.34E-37 2.69E-40 2.48E-39 136 717 "TKTL1,AXIN2,FZD9,USP31,PWWP2A,ADORA3,CASKIN1,HACE1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,APP,CDC14B,CASK,ARHGDIA,ZBTB10,DDX3Y,KIF1A,DOCK11,BCL7A,MTMR3,BTRC,FOXK1,CA8,CANX,RUNX1T1,CCNT1,ENTPD6,CDC27,DLGAP3,CLCN3,CLU,TMEM184B,CNN3,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,DMPK,USP3,CPEB2,DMTF1,PDCD6IP,FCF1,HEYL,SIDT2,PLEKHA1,EN2,ANKRD13B,RAB9B,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,CAMSAP1,RGPD5,MSANTD4,NCKAP1,ZNF559,RNPS1,RAB40B,GNAL,NEGR1,MSL1,RBPJ,DIPK1A,LAMP2,ARHGAP12,CHIC1,SCAMP5,MN1,CCDC80,MYO5A,OCRL,ETFRF1,PCMT1,PDE4D,PIK3R1,PRIMPOL,PSAT1,PPP2R5C,PTPRD,PLEKHB2,RBBP6,RET,RNASEL,ZFHX4,RNH1,TMEM100,SALL1,HSPA4L,CPEB3,ANKRD36,SOX5,TSPYL2,KANK1,GANAB,PRRC2C,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,TGFBR3,CABIN1,TPM2,TPM3,NR2C2,TUBB2A,CADM1,UBE2H,AMOT,VAV2,WIPF1,KLC2,ZBTB16,CSDE1,XKR7,WNK3,RTN4,ACTR3B" MicroRNA "CACTTTG,MIR-520G:MSigDB" "CACTTTG,MIR-520G:MSigDB" MSigDB 1.04E-40 5.83E-37 2.94E-40 2.71E-39 75 224 "CSMD3,APBB2,USP37,MARK4,ATP2B2,ADGRB2,JAZF1,CFL2,SOCS6,DNAJB5,CNR1,PCYT1B,ARMC8,AHCTF1,DCAF8,DBN1,PLEKHM1,MAGI2,DMD,DNM2,DMTF1,DNAJB6,DYRK1A,CELSR3,KMT5B,GOLGA7,EIF4G2,EPHA5,PTK2B,GTF2IRD2,NBEA,MSANTD4,OGA,TCERG1,TNRC6A,GRM7,KLF12,MAT2A,RSPO2,MYCN,NELL1,NHLH1,PRRX1,PPP3CA,MAPK9,PTPN13,RFX4,SALL1,ATXN1,CHD9,FNDC3A,SLC1A2,SLC6A9,NPAS3,ITPRID2,PLCB1,TBL1X,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,ZFP91,TRPS1,FLRT2,VLDLR,NSD2,DPYSL5,SLC30A3,CA10,EMSY" MicroRNA "CACTTTG,MIR-520H:MSigDB" "CACTTTG,MIR-520H:MSigDB" MSigDB 1.04E-40 5.83E-37 2.94E-40 2.71E-39 75 224 "CSMD3,APBB2,USP37,MARK4,ATP2B2,ADGRB2,JAZF1,CFL2,SOCS6,DNAJB5,CNR1,PCYT1B,ARMC8,AHCTF1,DCAF8,DBN1,PLEKHM1,MAGI2,DMD,DNM2,DMTF1,DNAJB6,DYRK1A,CELSR3,KMT5B,GOLGA7,EIF4G2,EPHA5,PTK2B,GTF2IRD2,NBEA,MSANTD4,OGA,TCERG1,TNRC6A,GRM7,KLF12,MAT2A,RSPO2,MYCN,NELL1,NHLH1,PRRX1,PPP3CA,MAPK9,PTPN13,RFX4,SALL1,ATXN1,CHD9,FNDC3A,SLC1A2,SLC6A9,NPAS3,ITPRID2,PLCB1,TBL1X,SATB2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,ZFP91,TRPS1,FLRT2,VLDLR,NSD2,DPYSL5,SLC30A3,CA10,EMSY" MicroRNA hsa-miR-563:mirSVR_highEffct hsa-miR-563:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-40 6.84E-37 3.45E-40 3.17E-39 93 350 "ACHE,NBAT1,KIAA1211,PTCHD1,KLHL13,KCTD16,C1QTNF3,PHF12,ASCL1,CAPRIN2,ASPH,ASTN1,BACH1,CAMK2D,ISPD,ABCG2,GDA,MICAL2,CSNK1G3,SOCS5,PNPLA8,ARHGAP32,LONRF1,ZC3H11A,AK5,ECM2,ELAVL4,EPB41L1,CLVS1,EFEMP1,KAT8,FGF13,POLK,GABRA2,JPH4,IGSF5,TCERG1,RAB30,ZNF782,SERP2,GRM1,RNFT2,ARHGAP36,TLX1,TCEAL6,SMAP1,GAREM2,ITGAV,KCNK2,CREG2,KLC1,SYTL4,NRBP2,SLC11A2,NUCB2,PPM1B,PRKACB,MDGA2,CNTLN,DBX2,RGS4,PBRM1,PNMA8A,ATP8B4,LGR4,RTN1,SCN8A,DZIP1,LRRC55,SLC8A3,ZNF334,SLC15A2,SLC20A2,SORCS3,ANKRD36,SNRPN,UNC80,KIF21B,NPAS3,STOX1,FGD4,VWC2,WDR7,TRIO,UBE3A,CLDND1,GUSBP1,PLPPR5,MFF,KCNAB1,FIP1L1,WNK3,SSPN" MicroRNA hsa-miR-762:mirSVR_highEffct hsa-miR-762:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.29E-40 7.23E-37 3.64E-40 3.35E-39 131 672 "CPNE2,ABCF1,CLK4,NDRG2,SLC12A5,DPY19L2P4,OLMALINC,SPOP,ARHGAP20,CNIH2,PKP4,TNRC6C,PPFIA3,ARNTL,CCDC74A,SLC2A11,DPY19L3,SYNJ1,KALRN,PTBP2,RUNX1T1,P2RX6,ARHGEF2,PLEKHB1,DNAJB5,ZNF385A,CPS1,SH2B1,NCOR1,CLIP3,SEC24C,CSF3R,UBXN2A,PUM1,PHF19,GIT2,SMG7,EXOG,FCF1,EFNA3,EGFR,EPB41L2,CLVS1,ZNF589,SLC9B2,PRKAG2,USP21,CAMKK2,AHCYL1,DISC1,KIAA1841,GCK,GGT7,GLYR1,LOXL3,GNAO1,TDRKH,PRLHR,CECR2,CLASRP,TOX2,ARHGAP36,HPSE2,HMGCL,TLX1,SMAP1,IL6ST,INPP5B,ZNF385B,LRRTM3,IPO5,HECTD2,MEIS1,CD200,MYO7A,NAP1L3,PAH,ZNF655,POLR2F,PPP2R5E,PKN2,WBP1L,TMEM104,PTPRD,RASGRF1,EXD2,CARF,YY1AP1,MAP6D1,KCNIP1,FAM192A,SCG5,SLC1A3,ARHGEF40,SIRT2,SON,SOX10,SP4,ERC1,SPTAN1,IQSEC2,NFASC,ATP10B,ST5,MPRIP,STAC2,ADHFE1,VAMP1,UNC5D,ZFP90,TRIM2,WASHC4,WDR7,NAT16,TF,MTMR14,HEY1,PIK3R5,ZNF346,ZMYND8,HSPBP1,UGT8,OSBP2,BCL2L13,MTCH1,CLDND1,CFAP298,TMEM178A,CAMK1G,ADAMTSL3,JPH3" MicroRNA hsa-miR-3130-5p:mirSVR_highEffct hsa-miR-3130-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-40 7.95E-37 4.00E-40 3.69E-39 115 529 "ASIC1,CSMD3,KIDINS220,PCDH10,KIF6,LGR5,MARK4,ATP2B1,DPY19L3,OSGIN2,CACNG1,SPAG9,TMEM257,DGKI,CDH18,TIGD7,MYL6B,AKAP7,SLC35F1,AKAP12,ANKRD44,CS,PITPNM3,ST18,LIN54,SIRPA,B3GAT3,DNAJB6,ATL1,HIPK3,PHF20L1,COQ7,CDKL3,F5,ZSCAN30,FER,AMOTL2,PDLIM5,CELF1,STAU2,GAD2,KIAA1841,TUBGCP4,ADAM28,GHR,DCLK2,GPD2,GPM6B,PSIP1,HAS2,MIER3,HPSE2,HMGCL,ZNF385B,KCNA2,KCNJ11,STMN1,VWA5A,MARK1,MEIS2,ZNF680,MYCN,MYO9A,FAM218A,CCSER2,DRAM2,PPM1B,PRKACB,PRKCZ,PTCH1,TMEM260,EML5,PPP2R3C,RAD51D,RGS7,MRPS18A,CCDC82,RORB,ELP2,RPE,ARMH4,ACER3,ABCA11P,SCP2,FHOD3,R3HDM2,SLITRK3,CNKSR2,ZKSCAN3,SORCS3,SMARCE1,USP33,TAB2,POGZ,SYNE2,PLCB1,TCF7,PCDHB10,FRYL,CCDC173,CRB1,HHIP,ARL10,HEY1,TPD52,KCNE5,NSD2,GUSBP1,HPS4,NAV3,TMEM163,WNK3,FBXO36,CAMK1G,VANGL2" MicroRNA hsa-miR-524-3p:mirSVR_lowEffct hsa-miR-524-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.52E-40 8.55E-37 4.30E-40 3.96E-39 100 405 "DGCR6,EMILIN3,ADD3,ESYT2,LRRC7,PDZD4,PITPNM2,AMPD2,ANK3,SEMA7A,CDC14B,SNAI3-AS1,NAE1,CACNB2,NGB,VXN,CCKBR,SCARB1,CHGA,CHRM1,IGLON5,PPP1R16B,ERC2,TOX,ZNF337,TBC1D5,LIN54,AIF1L,ARMCX4,PITPNC1,C8orf34,MAGI2,SRGAP3,WDR20,SLC29A4,HIPK3,TOMM40L,SUCO,SEMA6C,SEMA4D,PDLIM5,FAM49B,B3GAT1,ILDR2,AHCYL1,ZNF274,EML4,GRB10,GRID1,LINC00839,ZBTB49,ADAMTS6,LINC00667,KCNJ10,KIF5A,PAXBP1,SYT9,MN1,BLOC1S2,MXI1,HNRNPM,CDK18,ANLN,FAM216A,PLCB2,PLIN1,PLXNB3,SDK2,PPP1R1A,PPP2R5C,MAPK4,ZIK1,C1orf109,SLC25A48,CCDC82,KLHDC8A,ROBO1,TCP11L1,RYR3,ARX,SEPHS1,SLC11A1,SORCS3,INAVA,KDM4B,ZSWIM8,SPART,SSTR1,SS18,MPRIP,AJAP1,MLST8,SATB2,ZFPM2,TPM2,TRO,WIPF1,EML6,HNRNPA3,CPNE4" MicroRNA hsa-miR-4256:mirSVR_highEffct hsa-miR-4256:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-40 8.98E-37 4.52E-40 4.16E-39 117 547 "SDE2,ACADM,AS3MT,CDC7,GRAMD1B,PWWP2A,KIDINS220,CEP126,OGT,MAP4K3,CDK10,TMEM263,ARNTL,ALDH4A1,ATP1A2,STX16,MYOM1,BACH1,DCAF5,PTBP2,SYT6,NOG,CFL2,ABCG2,QKI,ARMC8,COX4I1,HS3ST5,LRIG1,ARHGEF10,PDE4DIP,GREB1,ARHGAP24,GIT2,TIAM2,ZC3H11A,SV2B,WDR20,CHRDL1,DMTF1,ABI1,FSD1L,F8,ZNF461,TESK2,RGPD5,SMC2,APOPT1,STAU2,GABRA2,ACSS1,WASF3,GLS,PCDH11X,INSM2,LNX1,GPM6A,FUT10,GPR37,PRDM5,HPSE2,HSF2,FAM95B1,C5orf24,ZNF385B,OLFM3,MMP16,WDR49,MOG,NDUFA5,NELL2,NTRK2,ZNF713,P2RX7,PCMT1,POU3F2,FSD1,TATDN3,MASP1,PTPRG,PTPRO,PID1,SUSD4,MORC4,ZFHX4,CCDC82,CARF,RORB,RPE,KIAA0895L,ATP8B4,SOX6,MRAS,ST3GAL3,CLSTN1,WDR47,ZKSCAN3,KIF21B,SP4,ATP10B,SS18,ZSCAN29,MCF2L,SYNE1,FRYL,TIAM1,MTMR14,TLL2,ERCC6L2,WIPF1,MICU3,ZNF189,TFIP11,PCDH15,NAV2,EPM2A,IFT88" MicroRNA hsa-miR-487a:PITA hsa-miR-487a:PITA_TOP PITA 1.76E-40 9.86E-37 4.96E-40 4.56E-39 78 245 "CSMD3,HECW2,ARHGAP20,PPP4R4,ASTN1,DDX3Y,CALB2,LDB2,REPS2,ZMYM4,SRSF11,FOXN3,TMEM184B,CNR1,CLOCK,GDA,DOCK4,GAPVD1,FRMPD4,DAPK1,YTHDC1,ZEB2,MAGI2,ZC3H11A,SMG7,SGSM2,PDCD6IP,DYRK1A,HIPK3,FAM13A,ELAVL2,ETV1,CAMSAP1,NPTN,CHL1,GAD2,CPLX2,MMADHC,PPARGC1A,ZNF638,GPM6A,SMAP1,ZIC5,AFDN,HCN1,PDE4D,CDK14,PIK3C2A,PDZRN4,MAPKAP1,EPB41L4B,PPP2R5E,KANSL1,PTCH1,MTMR10,FAM120C,RAB5B,RFX3,RFX5,RNF220,CARF,YPEL4,TMCC1,PDZD2,ARHGAP26,SPART,PLCB1,SYN2,SYT4,TAC1,RPGRIP1L,PUM2,SIRT1,KCNE5,ZNF711,EVI5,FAM13C,SMIM8" MicroRNA hsa-miR-1274b:mirSVR_highEffct hsa-miR-1274b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.01E-40 1.13E-36 5.67E-40 5.22E-39 107 463 "METAP1D,CSMD2,KLHL32,GRAMD1B,KIAA1211,TXNDC16,ADGRF5,CCDC146,UPRT,ALS2,DOCK11,NRP2,MTMR2,CALB1,CASC2,CLTA,CPS1,CS,MICAL2,RIMS2,HP1BP3,CEP170,DRD1,PDCD6IP,DSCAM,FAM135B,YAF2,GPR61,PHF20L1,MBNL2,TUBD1,KCNMB2,F8,ACSL4,ZNF589,CAP2,ANKFY1,SGIP1,GALC,NEK6,GART,WASF3,GATM,STON1,C1QL4,GRIK1,GRM8,RNF165,AP4S1,SOX21,ARHGAP36,AGBL5,HNRNPK,CFAP126,SMAP1,C2orf72,NME9,GPR62,CLVS2,KCNJ9,KLC1,AFDN,NEUROD1,NF1,SLC11A2,PDCD2,SLC10A4,FAM216A,MTRF1L,PURG,MED1,GRAMD1C,CNNM2,MDGA2,PTH1R,PTPRD,EML5,MARCH1,FIGN,RFX4,RIC8B,RNASEL,RPRD1A,ZNF532,CARF,STK32B,ATAT1,LRRTM4,SUPT20H,COPZ1,NTNG1,ZNF667,SNRPN,SOX2,ZBTB43,NPAS3,SPART,NXT2,ARHGEF9,WDR7,SLC44A1,TIAM1,SEZ6L,NPL,ZNF384,CELF4,FIP1L1" MicroRNA hsa-miR-920:mirSVR_highEffct hsa-miR-920:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.02E-40 1.14E-36 5.70E-40 5.25E-39 118 557 "CCDC85A,ADD2,SLC12A5,SLC44A5,GPR158,ADGRF5,ANK3,ALS2,CHID1,BCL2L2,CFLAR,ARHGEF25,CBR1,NIPBL,COL9A2,LETMD1,SLC35F1,CREM,HINFP,SEC24C,MICAL2,RUBCN,CCDC144A,HDAC9,PITPNC1,B3GAT3,CNIH3,RHOBTB1,WDR20,CHRDL1,SEZ6L2,TMEM35A,C8orf37,EIF1,SRRM1,ATP8A1,ZMYND15,FOLR2,HVCN1,CGREF1,DISC1,GART,PRLHR,PLCD4,GRM7,GUCY1B1,GPR45,USP54,ZNF678,KCNK3,STXBP5,NCOA7,ASPRV1,MATN3,CHIC1,CNOT4,NUCB2,NUMA1,GPR88,PDE3A,PDE4B,PDE4D,ZNF655,FAM216A,PLP1,MTRF1L,PPP2R2B,C1orf109,RFX4,RGR,RGS4,RNASEL,NEK11,ADAL,DGLUCY,PEAR1,COPZ1,FERMT1,BTBD3,SPHKAP,TET1,GKAP1,SMARCD3,NMNAT2,TSPYL2,SPART,LARP4,ADHFE1,VAMP1,POPDC3,DMXL2,SZT2,SLC19A3,HIF3A,AP4E1,THRA,MTMR14,ACTR6,TPM1,C9orf85,ZNF384,ZNF346,METTL3,UBE3A,GORASP1,CLDND1,INTS3,GAL3ST3,SLC17A7,FIP1L1,WNK3,EPM2A,DOCK8,ST7,KAT6A,CAMK1G,IFT88,NETO2" MicroRNA hsa-miR-15b-5p:Functional MTI Functional MTI miRTarbase 2.02E-40 1.14E-36 5.70E-40 5.25E-39 140 760 "TKTL1,AXIN2,FZD9,USP31,ADORA3,CASKIN1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,APP,CASK,ARHGDIA,ZBTB10,DDX3Y,ATP2A2,DOCK11,BCL7A,SYNJ1,MTMR3,BTRC,FOXK1,CA8,CANX,RUNX1T1,CCNT1,ENTPD6,CDC27,TBRG4,KMT2C,DLGAP3,CLU,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,DMPK,USP3,CPEB2,DMTF1,FCF1,HEYL,SIDT2,PLEKHA1,EN2,ANKRD13B,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,WAC,ZNF585B,CAMSAP1,MSANTD4,TBR1,NCKAP1,FAXC,RNPS1,RAB40B,GNAL,AP4S1,HNRNPK,NEGR1,MSL1,RBPJ,JAK1,LAMP2,ARHGAP12,CHIC1,SCAMP5,AFDN,CCDC80,MYO5A,HNRNPM,OCRL,ETFRF1,PCMT1,PDE4D,PIK3R1,PSAT1,PPP2R5C,QRICH1,PTPRD,PLEKHB2,RBBP6,ZFHX4,RNH1,TMEM100,SALL1,HSPA4L,CPEB3,DHX30,ANKRD36,MYCBP2,BEX1,TAB2,KANK1,GANAB,STXBP1,PRRC2C,VPS13A,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,TGFBR3,THRA,TPD52,TPM2,TPM3,NR2C2,TUBB2A,UBE2H,AMOT,VAV2,KLC2,ZBTB16,ZFAND5,CSDE1,XKR7,WNK3,PLSCR4,RTN4,UBE3B,NUP214,ACTR3B" MicroRNA hsa-miR-411:mirSVR_highEffct hsa-miR-411:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.22E-40 1.25E-36 6.25E-40 5.76E-39 116 540 "TMCC3,SLC44A5,ALCAM,BCAR3,ABCD2,DPP10,PPFIA2,PPFIA1,MAGEE2,NT5C3B,CACHD1,KIAA1614,WASF1,CALM1,PTBP2,CAST,ZBED1,CDH2,LRRFIP1,CCPG1,CHGB,JAM2,NRXN3,CLTB,SULT4A1,COL4A5,SLC25A27,SLC4A7,MAGED1,ACBD5,PREPL,RNF14,CSNK1E,VCAN,PDE4DIP,APPL1,PUM1,ZSCAN23,TCAF1,FRMPD4,FBXL5,CHRDL1,PDCD6IP,FRY,EIF4G2,TUBB3,ZSCAN30,UBE2E3,ATP2C1,ABLIM2,FYB1,ZMAT1,GABRA2,GCNT2,DBF4,GNAO1,GPD2,CCDC184,EML4,GRM3,KIF3A,HSP90AA1,HTR5A,MSL1,TUBB2B,ZNF680,MRPL42,SLCO1C1,PDCD2,OLA1,ZFYVE21,PPM1B,PPP2R5C,SAMD9,C1orf109,RALGDS,OXR1,RET,EXD2,SPIN3,ABCA11P,ATXN7,LINC00461,FERMT1,ELMO2,EFHD1,GKAP1,MAPKBP1,SP2,SP4,ENKUR,PBLD,CLSTN2,VAMP1,SYT4,DDHD2,DMXL2,SYNE1,PCDHB4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ATP13A2,AKTIP,TPD52,CLHC1,ELFN1,PLPP4,SYNC,WNK3,NHSL1,SLC39A12" MicroRNA hsa-miR-606:PITA hsa-miR-606:PITA_TOP PITA 2.33E-40 1.31E-36 6.56E-40 6.04E-39 86 301 "RALGAPA1,OSBPL1A,LRCH2,USP37,SHTN1,ZBTB10,SLC4A4,JAZF1,VXN,RUNX1T1,REPS2,DLGAP2,KMT2C,DNAJB5,QKI,COL9A1,AKAP5,SLC4A7,ACBD5,CSNK1G3,CNTNAP2,ST18,ARHGAP24,MATR3,DLG3,DMD,CPEB2,DYRK1A,EFNB3,RGS17,EPB41,EYA1,ACSL4,ATP8A1,AFF2,PPARGC1A,GPR34,FAM19A2,TOX2,ZHX1,MIER3,SMAP1,MBNL1,MN1,SCG3,NEXMIF,MYT1,ZC3H12B,NFE2L2,OPCML,NALCN,PIK3R1,HMGCLL1,LRP12,SCHIP1,LRRN3,PTPN13,FAM120C,TMEM255A,OXR1,RIMKLA,SFPQ,HSPA4L,PPM1E,NLGN1,CCDC88A,TRIM67,CPEB4,RCOR3,RIMS1,SOX11,SP4,SRPK2,NKAIN2,CAMTA1,DNMBP,TCF4,RBFOX2,TRPS1,UBE3A,DPYSL5,WNK1,SLC17A6,KLHDC1,SOCS4,SENP7" MicroRNA hsa-miR-143:PITA hsa-miR-143:PITA_TOP PITA 2.41E-40 1.35E-36 6.79E-40 6.25E-39 74 220 "KCNH8,TMEM132B,ADD3,ALS2,NUMB,BSN,CACNA1A,CALM1,LRBA,DCLK1,SRSF11,TAOK2,AKAP6,SLC35F1,CREB5,CSNK1G3,CTNND1,DMTF1,SLC12A6,PAN3,ETV1,FGF1,UBE2E3,SYT3,AHCYL1,CPLX2,GATM,GPD2,RNF165,KAT7,KLF12,MIER3,KCND1,MEF2C,MYO5A,MYO6,NEXMIF,CNOT4,PCMT1,TMOD2,PLIN1,STRN3,LRP12,RETREG2,TNPO2,PPP2R5C,RASGEF1B,MAPK7,PTPRB,KCNIP1,ELMOD1,COPZ1,SCAF8,PPM1E,TET1,LHFPL4,ARHGAP26,LARP4,STXBP1,NUDT10,ANKRD28,ANKRD12,WSCD1,TMEM121,TIAM1,SLC35A4,NSD2,KLC2,MKRN3,ZBTB38,TMEM237,NAV3,WIPF2,PHTF2" MicroRNA hsa-miR-491-3p:PITA hsa-miR-491-3p:PITA_TOP PITA 2.45E-40 1.38E-36 6.90E-40 6.35E-39 84 287 "CCDC85A,ADD3,PTCHD1,HECW2,SEMA6A,ALCAM,C6orf89,NCOA1,B3GALT2,JAZF1,CABP7,CANX,CBFA2T2,LRBA,ZMYM4,FOXN3,SYNPR,RAB33A,AKAP5,DOCK4,DGKB,SPOCK2,SNAP91,DMD,DYNC1I1,NR1D2,CPEB2,ABI1,PDCD6IP,DYRK1A,GOLT1B,EIF4G2,ELAVL2,FGF13,FOXO3,GABRB3,GK,PCDH11X,RAPGEF4,GRIA4,FAM19A2,MAP4K5,AGFG1,C5orf24,NKD1,LRRTM3,KCNA2,KCNC2,MARK1,MBNL1,CHIC1,MEF2C,ZC3H12B,NOVA1,PDE4D,POU3F2,KANSL1,FAM184A,FIGN,ZFHX4,CLIP1,RTN1,FNDC3A,CPEB4,MYT1L,LHFPL4,CDK19,LARP4,PRRC2C,PLCB1,SYN2,MTCL1,WASHC4,PUM2,TEX15,TEK,DICER1,SIRT1,SLC44A1,RBFOX2,TPM3,FMN2,SLC17A6,GOPC" MicroRNA hsa-miR-542-5p:mirSVR_lowEffct hsa-miR-542-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.48E-40 1.40E-36 6.99E-40 6.44E-39 107 464 "TTYH1,ACHE,CLK4,ALCAM,LRFN1,DPP10,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,APAF1,LGR5,CDK10,LINC00173,TMEM108,N4BP2L1,TTLL9,SLC25A14,CBLN1,IGFN1,LY86,SLC4A8,GAL3ST1,MFSD4A,NCAN,MATR3,MAML1,SNAP91,DLG4,DYRK1A,SGK2,RASA4,KCTD3,ECSIT,EZH1,STRADA,FGF14,SEMA4D,EFCAB2,AKAP3,ADGRA1,GABRB3,TRAF3IP2,ILDR2,DISC1,TCERG1,CBX1,INSM2,ADGRA3,ADAMTS8,FAM19A2,RNF165,IL6R,ITGAM,C1orf194,MID1,MYO7A,BEX5,NCAM1,SFR1,PAK3,PDE4B,SLC25A23,PLXNB3,RC3H2,PPP2R5C,SLC22A23,CNTLN,MTMR10,PTPRE,PEX5,CCDC40,RDX,RGS12,CLIP1,TMEM156,CASC3,FBXO11,FAM81A,SLC22A4,SMARCD3,ANKRD36,SNCB,DIP2A,GANAB,ZFR2,ANKRD28,EHBP1,OBSL1,TNS2,FAM200B,SPX,TGFBR3,ICAM5,LRRC8A,DCBLD1,LINC00689,VIPR2,NSD2,ZNF70,ZNF74,SH3GLB2,EMSY,PRDM2,PRDM8,SNX27,DNAH10,UBE3B,NHSL1" MicroRNA hsa-miR-195-5p:Functional MTI Functional MTI miRTarbase 2.49E-40 1.40E-36 7.00E-40 6.45E-39 127 639 "TKTL1,AXIN2,FZD9,USP31,ADORA3,CASKIN1,TBC1D14,TAOK1,TRMT9B,OGT,ARMC12,APP,CASK,ARHGDIA,ZBTB10,DDX3Y,DOCK11,BCL2L2,BCL7A,MTMR3,BTRC,FOXK1,CA8,CANX,RUNX1T1,CCNT1,ENTPD6,CDC27,CDC42,DLGAP3,CLU,TBPL1,BAG4,ZFP28,NCOR2,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,DMPK,USP3,CPEB2,DMTF1,FCF1,HEYL,SIDT2,PLEKHA1,ELN,EN2,ANKRD13B,ZNF391,VPS26C,ANKMY1,KATNAL1,EZH1,ZNF585B,CAMSAP1,MSANTD4,CAB39,NCKAP1,RNPS1,RAB40B,GNAL,NEGR1,MSL1,NKD1,RBPJ,JAK2,LAMP2,ARHGAP12,MBD1,CHIC1,SCAMP5,CCDC80,MYO5A,OCRL,ETFRF1,PCMT1,PDE4D,CAMKV,PIK3R1,PSAT1,PPP2R5C,RASGEF1B,PTPRD,PLEKHB2,RBBP6,RET,ZFHX4,RNH1,TMEM100,SALL1,HSPA4L,KIF21A,CPEB3,ANKRD36,KANK1,GANAB,PRRC2C,DNAJC9,SYPL1,FRYL,CYB561A3,DICER1,ZMAT3,TGFBR3,TPM2,TPM3,NR2C2,TUBB2A,UBE2H,AMOT,VAV2,WNT7A,KLC2,ZBTB16,CSDE1,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-1246:PITA hsa-miR-1246:PITA_TOP PITA 2.55E-40 1.43E-36 7.16E-40 6.60E-39 76 233 "AXIN2,PWWP2A,PCDH19,TAOK1,SEMA6A,USP37,ATP2B1,RNF182,BCL2L2,CALB1,CAMK2G,LDB2,LONRF2,CDH2,NRXN1,QKI,NIPBL,AKAP6,CREB5,PLCXD3,IP6K1,MAGI2,SMG7,DLG3,DYNC1I1,DYRK1A,YAF2,MBNL2,EGR3,SLC43A2,ERBB4,CLVS1,WAC,WASF3,CPLX2,FAXC,MSTN,ARFIP1,SESN1,FERMT2,ADAMTS6,MIER3,C5orf24,KLC1,LSS,CHIC1,ZC3H12B,NTRK2,WBP1L,PTCH1,TMEM255A,RDX,ROBO1,CSRNP3,LRFN5,SCN3A,FNDC3A,SEPHS1,CCDC88A,SLC12A2,FAM126B,SOX2,ZNF423,SRPK2,SYT11,SYN1,TCF4,PSD3,TPD52,CADM1,FAM155A,SLAIN1,ZIC3,SNX27,KCNAB1,FRMD6" MicroRNA hsa-miR-220b:mirSVR_highEffct hsa-miR-220b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.61E-40 1.46E-36 7.32E-40 6.74E-39 125 621 "RBM10,GRAMD1B,ADORA3,RTL9,LRRC7,PLA2G4C,DNAH17,KALRN,LRBA,RCBTB2,RAB28,COL4A5,ABI3BP,HS3ST5,CSF2RA,SEC24C,FEZ2,CSNK1G3,SUSD5,PDE4DIP,SLITRK5,CTNND1,CX3CR1,GPRASP1,DDX46,SMG7,SACS,SV2A,MAMLD1,DNM1L,GOLT1B,GPR61,EGR3,PAN3,GPHN,RASL12,TMEM132C,ST3GAL6,SLC37A3,UFM1,ATP2C1,CELF1,DACH2,NRG3,CHL1,ZMYND11,TUBGCP4,GFAP,KDM2B,GOLGB1,GPD2,CECR2,GRIA2,GRIA4,PLCD4,NR3C1,AP4S1,HNRNPK,OPALIN,SMAP1,MYLK2,SCIN,KCND2,STXBP5,MARK1,IL17D,PPM1L,NKX2-2,CNOT4,PAK3,PBX1,PCSK5,PDE4B,GNG2,ZNF655,PURG,SCHIP1,SEPT4,PPM1B,NKAIN4,PKIA,ZCWPW1,FIGN,RFX4,ARHGEF10L,EXD2,CARF,SNX22,RPL15,SPIN3,KCNIP2,RMI1,ATXN7,CASC3,SUPT20H,PPM1E,WDR47,SLC12A2,SLC12A4,MYO16,SPP1,TSPYL2,POGZ,ZNF302,SMOC1,SULF2,ZC3H4,VPS13A,DNAJC9,SYN2,TPCN2,DOCK9,ARHGAP9,C5orf64,TPM2,UBE3A,P2RY12,ZIC3,TRIM9,PRDM2,MDH1B,GOPC,DOCK8,SSPN,FAM198A" MicroRNA hsa-miR-216b:PITA hsa-miR-216b:PITA_TOP PITA 2.65E-40 1.49E-36 7.44E-40 6.85E-39 91 338 "RALGAPA1,CLK4,SLITRK1,SNX30,PTCHD1,PKP4,NRP2,VXN,RUNX1T1,SYNGR3,CFL2,SOCS6,CRY2,CLIP3,LRIG1,CHD5,FAM131B,DOCK4,MATR3,MAML1,HP1BP3,GUCD1,CPEB2,PDCD6IP,MBNL2,TENM1,ELAVL3,EPB41,SUCO,AFF2,GABRB1,ARFIP1,GPM6A,GPR19,EML4,PCLO,DDX19B,KLF12,HLF,ZIC5,OLFM3,CREG2,INSYN2,MEF2C,MID1,AFF1,NFIA,NFIX,CNTN3,PFKFB3,PMP2,SCHIP1,SDK2,FAT3,PPP3CB,PRKAB2,MAPK9,RELN,PEX5,RBBP6,RDX,RPE,TNFRSF19,SCAF8,SGK1,PPP1R9A,NTNG1,FNDC3A,SLC1A2,SLC1A3,PPP4R3A,SPHKAP,RIMS1,MBD5,TMCC1,FAM126B,SOX5,SOX11,TEX2,ZNF423,SMOC1,EPB41L3,LARP4,ERBIN,TCF4,CUX2,SYNE1,HHIP,VAV2,KCNT2,ADAMTS9" MicroRNA hsa-miR-576-3p:PITA hsa-miR-576-3p:PITA_TOP PITA 2.70E-40 1.52E-36 7.58E-40 6.98E-39 73 214 "ASIC2,ADD3,INTS2,APBB2,ATP2A2,ADGRB3,BCHE,BRSK2,LRBA,CCPG1,QKI,TMEM155,SLC35F1,ERC2,RIMS2,LONRF1,MFAP3L,SMG7,DLG2,SLC12A6,DYRK1A,ELAVL2,PLEKHA1,TMEM35A,STX2,PRKAG2,EFCAB2,STAG2,PPARGC1A,TOX3,KDM2B,STON1,GRIA2,C5orf24,ZIC5,KIF5C,INSYN2,LSS,CHIC1,KITLG,MSI1,NCAM1,P2RY1,PIK3CD,ANKRD16,STRN3,LRP12,PRRX1,NXPH1,PPP2R5E,PPP3CB,ATG16L1,MSANTD2,ZYG11B,LGR4,SGK1,FNDC3A,SLC8A2,SLC8A1,PDZD2,MYT1L,SOX5,SYT11,C3orf70,SYN1,SYPL1,DOCK9,CSMD1,TPD52,ZIC3,REEP1,LRP8,ADAMTSL3" MicroRNA hsa-miR-886-3p:mirSVR_lowEffct hsa-miR-886-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.86E-40 1.61E-36 8.02E-40 7.39E-39 108 473 "ABR,GPRIN1,AXIN2,BEND6,MTA3,GOLGA7B,AMPD2,EP400,AMER3,CDK10,MARK4,ASPH,ATP1A1,CADM3,DPY19L3,SNAI3-AS1,CACNA1D,CALB2,KALRN,HAP1,TRIM41,CBS,METTL6,CBFA2T2,DGKI,DLGAP1,EPS15L1,DNAJB5,TMEM184B,MAP4K4,CABP1,AKAP12,RIMS2,GPSM1,B3GAT3,LYPD1,GUCD1,PLPPR4,SLC29A4,DNM2,DPH1,DPYSL2,DTNB,EDNRB,MBNL2,RABEPK,EXTL1,RACK1,ZNF589,CAP2,ERGIC3,GLYR1,GLS,C1QL4,CLASRP,PTPN5,GSTM5,IGSF21,LRRC25,SCRT2,IL11RA,KCNB1,MBP,MEIS2,MOBP,PTOV1,MTR,NELL1,PCBP3,P2RX7,SDK2,PPARA,PPP2R5C,PRKCG,WBP1L,CCDC40,RAP1GAP,RNH1,ARMC5,RAVER2,TRIM46,FOXRED1,FERMT1,ZNF365,SMTN,SLC11A1,SNRPN,FAM219A,NFASC,ADHFE1,ACSBG1,ZC3H4,VPS13A,ADAMTS17,TPCN2,HIF3A,DICER1-AS1,LEFTY2,FBXL16,ACTR6,C5orf64,TNNT1,PPIL6,RPRM,MEIS3,SEMA3B,LINC00632,ST7" MicroRNA hsa-miR-1236:PITA hsa-miR-1236:PITA_TOP PITA 2.99E-40 1.68E-36 8.37E-40 7.71E-39 77 240 "NLGN4X,SPOP,BSN,CACNA1E,CAMK2A,CAMK2G,FMNL3,CHN2,KMT2C,CLCN3,NRXN1,SH2B1,CRY2,FAM131B,POM121,SRGAP3,DLG3,DLG4,DPH1,PDCD6IP,DYRK1A,EBF1,RBM12,PAN3,CACNG3,TAOK3,DLC1,SUCO,STAG2,CHL1,NCKAP1,PCDH17,IL1RAPL1,KAT7,ADAMTS6,CELF3,ATXN2L,KLF12,ZIC5,BRINP3,KCNN3,PACRG,MAP2,NCAM1,NTRK3,PLP1,ANKRD16,GRAMD1C,BCAS3,FAM120C,FAM184A,FBXW7,ZC3H14,NCBP3,SCN2A,NLGN4Y,PPP1R9A,CPEB3,DOCK10,FBXO11,EPN2,RCOR3,PDZRN3,ERC1,SS18,ARHGEF9,ANKRD28,TCF4,FBXL16,RBFOX2,FAM155A,NSD2,ZIC1,NAV3,WIPF2,SLC17A6,PAK5" MicroRNA hsa-miR-4312:mirSVR_highEffct hsa-miR-4312:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.24E-40 1.82E-36 9.08E-40 8.37E-39 113 516 "KIDINS220,AP2A2,INTS2,ALK,PPFIA1,SUGT1P4-STRA6LP-CCDC180,BCAS1,TNRC6C,MIER1,CACNB4,KALRN,KRIT1,CDC27,IGFBP7-AS1,ARMC8,SLC4A8,CNRIP1,CP,CHD1L,MROH8,ARHGEF10,NCAN,PHF14,CTNND2,NRSN1,TCAF1,PABPC5,CNIH3,BLOC1S6,EXOG,IRAK4,GPHN,CEP85L,FDFT1,FER,APOPT1,KHDRBS3,ADAM28,LYVE1,RUNDC3A,ZNF276,ZNF638,GRIA2,GRIA4,NKD1,LRRCC1,SCIN,ITGAM,METTL21A,OLFM3,CLVS2,KCNJ11,KIT,NCOA7,MAP2,MBD1,RSPO2,NODAL,CNOT4,DNHD1,OXTR,PLXNB3,PRKACB,FITM2,PSMA6,SYTL2,WDR25,CNTLN,PLEKHB2,RET,PBRM1,GSTCD,MCMBP,PAQR6,ABCA11P,WLS,ZNF331,AP1AR,SAFB,SCN3A,NLGN4Y,FERMT1,PAAF1,ZNF365,SLC6A8,ZNF430,SLC8A3,MYH15,RIMS1,SNRPN,KDM4B,KIF1B,TAB2,ERBIN,ADHFE1,PLCB1,TBL1X,ANO4,SLC44A1,TMPO,SYNPO2,RUNDC3B,UBE2H,GORASP1,CELF4,ZNF154,ANKS1B,MAP3K12,FAM13C,DOCK8,PHTF2,NUP214,SLC4A10" MicroRNA hsa-miR-591:mirSVR_highEffct hsa-miR-591:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.44E-40 1.93E-36 9.63E-40 8.87E-39 105 449 "ACADM,NCKAP5,ADAR,SLITRK1,ADGRF5,ALCAM,ASPH,CAMK2D,INA,CD38,CDO1,MS4A7,SYNPR,CNOT8,QKI,ATRNL1,VAC14-AS1,DZIP3,EDRF1,IST1,DGKG,RHOBTB1,ZNF582-AS1,DNAH9,DMTF1,ARRDC4,AASDH,WDPCP,EDN1,EPHA5,SRRM1,ABCA8,CACNG3,TESK2,FGF11,MEX3B,STAMBP,OGA,MEGF11,GABRA2,GCNT2,ADAM28,TXNL4A,PCDH11X,GNAS,GRM3,GRM5,GRM7,GSTM5,MFSD2A,GUCY1B1,MIER3,INSM1,KLHL23,KCNK2,KCNN3,KIT,PAXBP1,ARHGAP12,MBNL1,ADAM22,HCN1,NTRK2,PDE4D,GPR85,CDK14,EPB41L4B,SLC36A4,PPP3CB,RANBP3L,MAPK10,SIDT1,PEX5,SUSD4,ZYG11B,RET,KLHL11,RNASEL,SETD5,LRRK2,SCN3A,PPM1E,FBXO11,ZNF365,SPHKAP,LIMCH1,MBD5,UNC80,ZC3H13,ATP10B,GANAB,ASTN2,ZEB1,PCDHB6,FRYL,FAM200B,PMS2CL,ERCC6L2,SYNPO2,RUNDC3B,TUBB2A,ZNF177,MFF,FXR1,FAM198A" MicroRNA hsa-miR-3186-5p:mirSVR_lowEffct hsa-miR-3186-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-40 2.13E-36 1.06E-39 9.78E-39 99 401 "SYS1,HACE1,WDR35,HFM1,MRTFA,ANK2,CNIH2,PHYHD1,MADD,ARHGDIA,PLA2G4C,ASPH,CCAR2,ADGRB2,MIR9-3HG,CFLAR,SYNJ2,CACNA1D,BRSK2,CBLN1,NRXN3,IGLON5,IQCK,FAM169A,CTH,CFAP61,DCAF4,RUBCN,DAPK1,SIRPA,MAMLD1,ABCC5,EDN3,PHC2,LRRC17,NCALD,CHST15,FCGRT,SUCO,PCYOX1,ERGIC3,FAM120B,GLYR1,GRIA4,GRIK1,GRM1,CLASRP,ATOH8,FRMD5,NEGR1,CELF5,SCIN,KCNN3,MID1,SLC11A2,PDE1A,PFKFB3,ANLN,SNX10,JAKMIP1,PCDHB17P,PRKCG,PSMD13,PIGG,RALGDS,KHDRBS2,RIC8B,LINC00461,TNFRSF19,TRIM46,FOXRED1,SH3GL3,SLC8A3,NAPB,RCOR3,ANKRD36,INAVA,CMTR2,SNRPN,SON,SOX3,KIF21B,IQSEC2,MESP1,STXBP1,FNDC9,CNTN2,KIAA1107,TBCEL,CYB561A3,CDH22,TPM4,TRO,BEST1,SF1,PRDM2,LINC02210,SEMA3B,LAS1L" MicroRNA hsa-miR-500:PITA hsa-miR-500:PITA_TOP PITA 4.31E-40 2.42E-36 1.20E-39 1.11E-38 89 325 "HECW2,PCDH19,CACHD1,ZFYVE28,DDX3Y,SLC4A4,FUBP1,QKI,RCHY1,CREB5,CS,ERC2,RIMS2,RIMS3,DCC,YTHDC1,DDX46,G3BP2,CASP8AP2,RBM12,ELAVL4,PCOLCE2,CALCRL,ERBB4,EYA1,DLC1,FGF12,PRKAG2,DCTN2,ATP6V1H,FUT9,C15orf41,GPM6B,NR3C1,CIT,RNF165,HAS2,MIER3,NEGR1,HES5,LRRTM3,MBNL1,LRP1B,AFDN,HCN1,GPR85,XRN1,SMOX,STRN3,NXPH1,POU3F2,PPP2R5E,PTPRD,TMEM145,RDX,ZMAT4,FIGN,RFX3,ROBO2,LGR4,SATB1,SCN3A,CASC3,PPP1R9A,ST6GAL1,SLC6A1,PKNOX2,CCDC88A,SLC12A2,RCOR3,SOX11,CDK19,LARP4,ERBIN,GSE1,SYN1,TAC3,ANKRD12,SATB2,RPGRIP1L,PSD3,ZNF384,UBE3A,AMOT,ZIC2,MICU3,ZBTB38,SYNC,TMEM178A" MicroRNA hsa-miR-1245:mirSVR_highEffct hsa-miR-1245:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.39E-40 3.03E-36 1.51E-39 1.39E-38 123 607 "CSMD3,KIAA1211,HECW2,PCDH10,ANK3,LCORL,VAT1L,APP,STK33,KSR1,CASTOR3,MTMR2,C5,RAB29,CACNA1D,INA,CDO1,RCBTB2,CLTC,QKI,AKAP7,ARHGEF10,VCAN,ZSCAN23,KIAA0586,ARMCX4,RHOBTB1,RABGAP1L,GOLT1B,SYT15,PHF20L1,AASS,COPS4,EPB41L2,RCAN2,GPHN,PIPOX,ADGRV1,SUCO,SYNCRIP,ATP2C1,MSANTD4,SARAF,TRAF3IP2,HBS1L,BRPF3,KIAA1841,GK,RAB40B,GRB10,GRIA2,DIDO1,SERP2,GRM7,HMGCR,HTR2A,JAK1,METTL21A,VWA5A,MOBP,MOV10,ADAM22,NAP1L2,NAP1L3,NF1,NFE2L2,OCRL,PCSK1,HMGCLL1,PURG,MAPKAP1,WDR25,PIGG,PTHLH,TMEM260,TMEM255A,OXR1,RDX,ZMAT4,RET,RAVER2,ZC3H14,ACER3,RTN1,SATB1,ATXN2,LRFN5,LRRTM4,FNIP1,ITSN1,SH3GL3,CPEB3,FNDC3A,SLC2A5,IFT122,RIMS1,SP4,CLUAP1,KDM4C,LMO3,SEPT3,AJAP1,TMEM150C,TBCEL,ANO4,ITGB3BP,TMPO,TPM3,CADM1,FAM155A,UGT8,VLDLR,GPR158-AS1,EML6,SYNC,PRDM2,CSDE1,ADAMTS9,WNK3,GOPC,FAM13C,RNF170,FRMD6" MicroRNA hsa-miR-1228:mirSVR_highEffct hsa-miR-1228:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.03E-40 3.39E-36 1.69E-39 1.55E-38 111 502 "SYS1,ACTN1,ARID1A,CCDC85A,ADD2,LRRC7,MRTFA,DPP10,PHF12,PKP4,BCAS1,RGS20,ATP1B3,DCAF5,BID,BMP7,JAZF1,CACNA1E,KALRN,TRIM41,SPAG9,CDH10,L3MBTL4,SOCS6,NRXN1,NIPBL,IGDCC3,RNF14,SLC32A1,ABCG1,CSNK1G3,PHF14,EDRF1,TBC1D5,DGKB,SGSM2,DNM1,ARRDC4,RASA4,ING4,TMEM35A,CALCRL,EN2,DENND4A,ZNF549,EYA1,RPS6KC1,FGF12,FOXG1,POMT1,ST6GALNAC3,DKK3,GABRB3,GAD2,C15orf41,DISC1,ATP8A2,ADAM28,TCERG1,OS9,DCLK2,BVES,TMEM179,HPS5,TNFAIP8L3,EID2B,IL11RA,KCNA4,MAT2A,MSRA,THYN1,PAX6,PCDH9,PCMT1,PRTG,PFKFB3,ZNF655,ING3,PRKACB,SLC26A11,VPS13C,ZYG11B,ZFHX4,SPIN3,CLIP1,MIR124-2HG,LRRTM4,SLC2A5,CPEB4,KDM4C,TAB2,SS18,TTBK2,RGL1,SYN2,SYT4,SYNE1,DOCK9,THRA,TJP1,TPM1,TSC1,CADM1,PLEKHH2,USP1,RBFOX3,XRCC4,EMSY,UBE3B,CASC15,JMJD1C" MicroRNA hsa-miR-10a:mirSVR_highEffct hsa-miR-10a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.43E-40 3.61E-36 1.80E-39 1.65E-38 123 608 "KIAA1211,KIDINS220,ALCAM,LTBP4,FAM135A,MRTFA,CCDC146,UPRT,IGDCC4,ALDH7A1,DOCK11,SGCE,NFS1,CCNH,CLTA,CNTFR,CNTN1,ABI3BP,SLC35F1,SEC31B,NCOR2,RIMS2,USP6NL,GAPVD1,HP1BP3,KIAA0753,CEP170,MAGI2,DDX46,DSCAM,EDN3,FCF1,YAF2,PHF20L1,EGFR,ELAVL2,EIF1,EPHA5,SCML2,RACK1,CEP78,CAP2,SYNCRIP,UFM1,ATP6V1H,GAD1,ZMYND11,NEK6,GART,TUBGCP4,GLS,RAPGEF4,C1QL4,GRIK1,RNF165,LINC01551,ZHX1,HMGCR,SMAP1,IGSF1,KCNA6,KCNK2,KLC1,LIMS1,ARHGAP12,EFHB,AFDN,MYO9A,CNOT4,HCN1,SLC10A4,XRN1,FAM216A,HMGCLL1,PURG,LRP12,EPB41L4B,POU3F2,PPP3CB,RAB39A,VPS13C,MDGA2,ELOVL2,ERI2,FIGN,RPRD1A,TMEM206,SPIN3,STK32B,ATXN2,SEC14L1,ITSN1,CCDC88A,SLCO1A2,SPHKAP,ZNF667,RCOR3,SON,PDZD2,SOX1,DOK5,NPAS3,POGZ,NXT2,PRRC2C,DNAJC9,TRIM2,SYNE1,PUM2,FAM200B,TIAM1,TPD52,DCBLD1,CADM1,SLAIN1,ZIC3,ZNF154,ZNF189,PLPPR5,SYNC,SLC30A4,WNK3,PDSS2" MicroRNA hsa-miR-138:PITA hsa-miR-138:PITA_TOP PITA 7.59E-40 4.26E-36 2.12E-39 1.95E-38 80 263 "SYS1,UNC5A,SEMA6A,ANK1,JAZF1,USP6,CNOT8,KMT2C,ZNF385A,SLC35F1,SNCAIP,SOCS5,RIMS3,MAML1,ARMCX2,ZEB2,MYEF2,SMG7,CALN1,DNAJB6,EFNB3,CELSR3,KMT5B,RCAN2,ANKRD13B,CLVS1,ST3GAL6,NBEA,SRRM4,GGT7,PPARGC1A,FERMT2,PCLO,CIT,MIER3,SLC6A17,KCNK3,KCNMA1,MSI1,NEXMIF,PABPC1L2A,NFIX,NPTX1,PDE3A,GPR85,GNG2,CDK14,EPB41L4B,VSTM2L,RELN,UHRF1BP1,PTK2,USP47,MSANTD2,SH3GL2,YPEL4,KBTBD4,CPEB4,RCOR3,SNCB,ERC1,SPTB,CDK19,SEPT8,KANK1,SULF2,NSFL1C,UNC5D,ADGRL3,TBL1X,TCF4,KIAA0930,AHCYL2,SIRT1,TPM4,TRPS1,MEAF6,ZIC1,SLC17A7,JMJD1C" MicroRNA hsa-miR-30c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.62E-40 4.84E-36 2.40E-39 2.21E-38 113 521 "SDE2,CDC7,TAOK1,SEMA6A,MARCH4,PCDH10,ZNF687,USP37,MARK4,ATM,STX16,ATP2A2,DPY19L3,ST3GAL5,CAMK2D,AIFM1,CDC42,CFL2,ARHGEF6,SLC4A7,TBPL1,BAG4,PNKD,PREPL,CREM,NCOR2,CSF1,CSNK1E,GAPVD1,HDAC4,MATR3,ZEB2,POM121,SACS,DPYSL2,FEM1B,CELSR3,MRO,ABI2,ASB3,KCTD3,DCTN4,EPB41,SCML2,DLC1,CHST15,FOXG1,FOXO3,CELF1,MSANTD4,HHIPL1,OGA,GAB1,IP6K3,RNPS1,DBF4,TNRC6A,EML4,MIER3,ELOVL5,HNRNPK,HSP90AA1,JAK1,LIFR,SMAD1,LYPLAL1,MTTP,MTR,MXI1,NAP1L1,OPHN1,CAMKV,PKM,NLE1,MED1,PPP3CB,PRKAB2,MAPK8,UHRF1BP1,REV3L,SEC61A2,RNF220,NUDT11,PBRM1,SETD5,ALG9,PCMTD2,SBF1,TRA2B,BTBD7,CPEB4,ARFGAP1,SMARCE1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,ELOVL4,PLCB1,ARHGEF12,SLC35G2,GZF1,NACC2,ZMYND8,KLC2,XPO1,MKRN3,ZFAND5,CSDE1,RTN4,PHTF2,ZDHHC20" MicroRNA hsa-miR-3941:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.24E-40 5.19E-36 2.58E-39 2.37E-38 102 429 "CSMD2,ADCYAP1R1,ESYT2,TAOK1,ATP2A2,BACH1,BSN,CA8,TBRG4,CFL2,B4GALT6,TBPL1,BAG4,ANKRD44,MYADM,RIMS3,SPOCK2,DBT,MED24,KLHL3,SV2B,EGR3,SORBS3,EIF5,C8orf37,TUBD1,CHST15,SGIP1,ZBED3,MPP6,SYT17,GCK,SRCAP,PPARGC1A,RAPGEF1,DIDO1,PARD3B,CACFD1,NR3C1,IL1RAPL1,HLF,ZIC5,SCIN,IL6ST,ZNF678,KCNA4,KCNB1,KCNJ3,KLHL23,KCNK1,KIF5C,SFXN5,SYTL4,FGFBP3,MOBP,NEXMIF,NAP1L1,TMOD2,PIK3R1,CRLS1,PPP2R5E,SNRK,RDX,ZMAT4,C12orf49,STX1B,SBF1,CSRNP3,SLC12A2,SLC22A4,ZFP1,KIF13A,ZNF415,FAM126B,WDTC1,UNC5B,SS18,AJAP1,NECAB1,GPRIN3,SIK3,HHIP,SLC44A1,DDHD1,BEX4,DOK6,NR2C2,ZNF610,UBE2H,UBTF,UGT8,WNT7A,SF1,NDRG4,CRB2,ZXDA,LRP8,ADAMTS9,WNK3,MVB12B,FAM198A,SPATA13" MicroRNA "ACTGCCT,MIR-34B:MSigDB" "ACTGCCT,MIR-34B:MSigDB" MSigDB 9.81E-40 5.51E-36 2.73E-39 2.52E-38 71 205 "PLEKHG5,ADCY2,TMCC3,ADORA2A,AP1B1,KCTD16,TAOK1,ALCAM,ANK2,CNTNAP1,ATP1B3,JAZF1,WASF1,EVI5L,MAGI1,CACNA2D2,FOXN3,RAB3C,MYRIP,CTNND2,PPP6R2,ST18,TOX,ELMSAN1,ARNT2,RBM12,CELSR3,TENM1,PLEKHA1,SUCO,FAM49B,ARPP21,IQGAP2,GRID1,GRM1,CELF3,ATXN2L,KLF12,SHISA6,ICA1,INSM1,MAN2A2,MAT2A,MITF,MSI1,NEUROD1,NFIX,CNOT4,NPTX1,OCRL,PDGFRA,MAPK4,PTPRG,RDX,ARHGEF10L,RIC8B,ELMOD1,ITSN1,CPEB3,FAM219A,MYCBP2,RAP1GAP2,ANKRD12,MTCL1,TRIM2,TCF12,AHCYL2,RIMBP2,LMAN2L,NAV3,NETO1" MicroRNA hsa-miR-34c-3p:PITA hsa-miR-34c-3p:PITA_TOP PITA 9.91E-40 5.57E-36 2.76E-39 2.54E-38 76 237 "SLC12A5,MTUS1,MARCH4,ATP2B1,CALB1,RUNX1T1,KCNAB3,CFL2,CHM,SYNPR,AKAP6,DOCK4,GAPVD1,RHOBTB1,CPEB2,ABI1,MBNL2,TENM1,ELAVL2,RCAN2,FHL1,SUCO,FAM49B,NPTN,GABRG2,NCKAP1,ARFIP1,PCDH17,GLS,PCDH11X,GPM6A,GRM3,KIF3A,MAP4K5,ZHX1,FRMD3,MIER3,DHX35,KIF2A,MAP2,MARK1,NEXMIF,ZC3H12B,GPR137C,PDE4D,PLCL1,TRHDE,STRN3,KANSL1,PTPRD,PTPRE,ARID4A,RBBP8,RPE,PEAR1,SOX6,MRAS,NTNG1,MAGI3,CHD9,FNDC3A,SLITRK3,SLC8A1,CCDC88A,SNCA,MYT1L,ARHGEF9,SYN2,SYT1,PCDHB3,PUM2,AKTIP,TRPS1,USP1,LAMP5,SLC38A1" MicroRNA hsa-miR-516b:PITA hsa-miR-516b:PITA_TOP PITA 1.09E-39 6.11E-36 3.03E-39 2.79E-38 69 193 "SYS1,ADD3,AMPH,DPP10,ATP2A2,BCL2L2,CACNA2D1,CACNB2,DCLK1,FOXN3,FAM19A5,MAP4K4,IST1,CTIF,B3GAT3,SRGAP3,DMD,CPEB2,PDCD6IP,EFNB3,ABI2,GOLGA7,RGS17,EPHB1,AGAP3,FOXO3,GAD1,GPR162,TOX3,GPM6B,GRIA2,GRIA4,GRIN2D,GRM3,BACH2,ARHGAP12,SYT9,MEIS1,MPP2,GIT1,MYO5A,NEFM,PCDH9,PDGFRA,PDYN,OLA1,NLGN3,PCDH18,PMP22,NCBP3,FAM214B,HECW1,PEG10,POGZ,ELOVL4,GSE1,ADGRL3,TRIM2,SZT2,SLC44A1,RBFOX2,CADM1,CELF4,POLR3H,ZFAND5,EVI5,KAT6A,MSRB3,ST8SIA2" MicroRNA hsa-miR-10a-5p:Functional MTI Functional MTI miRTarbase 1.16E-39 6.52E-36 3.23E-39 2.98E-38 106 463 "ERMN,SLC24A4,INTS2,AMPD2,LRFN1,C6orf89,API5,ZBTB10,ATP1A2,SYNJ1,C5,BTRC,ZNF445,ABCG2,CCDC151,C2CD2,CREB5,CRY2,NCOR2,IPCEF1,CTNND1,USP6NL,CENPL,TMEM170A,MYEF2,MTX3,DLG4,MED12,NR1D2,DPYSL2,FEM1B,EIF1,EPB41L2,ADGRV1,FGFR1,SPECC1,CHL1,SEPT9,MSL3,GNAL,LILRA2,PTPRT,ARHGAP19,SYNPO,HSP90AA1,IGSF1,IL12A,KLHL23,LSS,MBD1,MTR,NAP1L1,NPTX1,SLC11A2,OCRL,PDPK1,XRN1,MED1,MAPK8,RELN,PSMD13,CNTLN,ELOVL2,PTPRG,PLEKHB2,RPRD1A,KLHDC8A,RPL15,NCBP3,FOXRED2,CSRNP3,SFPQ,TRA2B,ZFP30,KIF21A,URGCP,IGSF9B,SON,LHFPL4,CDK19,KANK1,FAM168A,PRRC2C,C12orf76,FAM208A,TRIM2,PUM2,AHCYL2,HHIP,TIAM1,NACC2,TPM4,NR2C2,RUNDC3B,CADM1,UBTF,BCL2L13,MEAF6,CFAP298,ZNF708,LYPD6,ZFAND5,TUBA1A,CAB39L,FAM219B,TTC7A" MicroRNA hsa-miR-1279:PITA hsa-miR-1279:PITA_TOP PITA 1.38E-39 7.78E-36 3.85E-39 3.55E-38 76 238 "SLC12A5,BEND6,NLGN4X,GPR158,HECW2,CADPS,SYNJ1,BTRC,SEPT7,REPS2,CNTN1,PCYT1B,HAPLN1,ATRNL1,RIMS2,ARHGAP24,DAPK1,DDX46,SMG7,SACS,G3BP2,CPEB2,ABI1,FAM135B,MBNL2,EGR3,RGS17,EMX2,ERBB4,PRKAG2,TACC2,GABRB3,GABRG2,GPR162,GFRA1,FERMT2,RAPGEF4,MIER3,ELOVL5,IGF1,KCNA1,MBD1,MGAT3,MYO5A,NCAM2,NEFM,NEFH,NRCAM,NTRK3,CLDN11,CNTN3,PDE4D,PDGFRA,PTK2,TMEM255A,RDX,LGR4,NLGN4Y,WDR37,PALLD,SOX11,PLCB1,SYT1,ANO4,TCF12,DOCK9,AKTIP,SLC44A1,TRPS1,TSC1,CADM1,UBE2H,LYPD6,EMSY,MSRB3,FXR1" MicroRNA hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 1.63E-39 9.13E-36 4.52E-39 4.16E-38 91 345 "KCNH8,ADCYAP1R1,ADD3,CACHD1,KIAA1614,MARCH3,INSYN2B,N4BP2L1,DST,BSN,CACNA1A,CALM1,ARHGEF1,QKI,HECTD1,NRG2,CSNK1G3,SDC3,CTNND1,RIMS3,DAPK1,JAKMIP2,DLG3,RPS6KL1,CPEB2,DOCK2,DTNB,EBF1,PAN3,EPS8,EFS,MRVI1,CORO2B,FGF1,MEX3B,CAMKK2,AHCYL1,ATP8A2,FAXC,ALDH1L1,GHR,GPD2,PTPRT,KAT7,FRMD5,KLF12,HMGCR,HTR2A,MSL1,IL6R,KCNB1,KCNC1,KCND1,LIFR,NCOA7,AFF1,MYO6,NOVA1,NOVA2,KCNK10,PC,PCMT1,PDE3B,PDGFRA,LRP12,RASGEF1B,MAPK4,MAPK7,CNNM2,APTX,QDPR,FIGN,CYB561D1,SCN2B,HSPA4L,SCAF8,PPM1E,ASAP3,ARHGEF40,ARHGAP26,CLASP2,LARP4,PHLDB1,FAM168A,ANKRD12,PSD3,CBX5,FNDC5,KLC2,RICTOR,PHTF2" MicroRNA hsa-miR-942:PITA hsa-miR-942:PITA_TOP PITA 1.82E-39 1.03E-35 5.07E-39 4.67E-38 88 323 "GPR158,SPOP,PITPNM2,ANK1,ATP2A2,NOL4,BTRC,CLCN3,NRXN1,QKI,HECTD1,COL4A5,CRY2,JAKMIP2,ZEB2,WDR20,CDON,CPEB2,EDN3,PHC2,RBM12,PHF20L1,EGR3,PAN3,EPB41L1,NRN1,ZNF589,SEC24B,FGF13,AFF2,AHCYL1,C15orf41,CPLX1,TCERG1,CIT,IL1RAPL1,HLF,AGFG1,HSF2,ZIC5,KCND1,KCNMA1,MAT2A,MSI1,NEXMIF,NCAM1,ZC3H12B,NTRK3,OPCML,PALM,PCDH9,XRN1,PPP2R5E,KANSL1,MAPK10,SNRK,PTPRD,ATXN1,LRRTM4,BTBD3,CPEB4,SMARCA4,SOX11,ZBTB43,CLASP2,MAPK8IP3,NECAB1,PLCB1,SYN1,FBXW11,ATMIN,WSCD1,TCF7L2,ZEB1,THRA,TLL2,HEY2,TNS1,RBFOX2,AMACR,FLRT2,PCDH20,LRP8,HNRNPA3,MSRB3,CBLN2,SLC4A10,SENP7" MicroRNA hsa-miR-633:PITA hsa-miR-633:PITA_TOP PITA 1.92E-39 1.08E-35 5.33E-39 4.91E-38 80 266 "GALNT13,SLC12A5,GPR158,PCDH19,SHTN1,AQP4,MTMR9,NIPA1,CACNA1A,CAMK2G,PRC1,KRIT1,USP6,CIART,B4GALT6,JAM2,CNN3,AKAP6,SLC4A7,AHCTF1,MYRIP,CEP170,G3BP2,CPEB2,ABI1,TENM1,EPB41L2,DLC1,KIAA1109,OLFM1,ATP2C1,CAB39,FAXC,PPARGC1A,GPD2,STON1,GRM1,MIER3,HLF,GABARAPL2,ZIC5,DOCK7,MBNL1,KITLG,NFE2L2,NFIX,NOVA1,GPR137C,XRN1,PCDH18,STRN3,LRP12,DRAM2,MTMR10,PTPRD,ROBO1,RORB,ATXN1,SCN2A,FBXO11,NLGN1,SORCS3,SON,MYT1L,CDK19,NKAIN2,NECAB1,SYT1,ANKRD28,ANKRD12,ACSL6,VWC2,TCF4,DICER1,NR2C2,TRPS1,UBE2H,UBE3A,TMEM237,KAT6A" MicroRNA hsa-miR-142-3p.1:TargetScan hsa-miR-142-3p.1 TargetScan 1.96E-39 1.10E-35 5.45E-39 5.02E-38 81 273 "FMNL2,RNF157,ANK3,MAP4K3,PHF12,APC,CASK,ARNTL,ATP2A2,MTMR9,BACH1,PROM1,ARHGEF2,CFL2,CLTA,QKI,HECTD1,ACBD5,CLOCK,CTNND1,PUM1,COPS7A,NR1D2,CPEB2,ABI2,PAN3,LRRC17,ANKFY1,AFF2,GAB1,GFAP,GHR,GNAS,EML4,DIDO1,NR3C1,IL1RAPL1,KAT7,BACH2,HMGB1,C5orf24,IL6ST,ITGAV,ITPKB,ARHGAP12,MAP2,MARK3,LRP1B,MEF2C,MEIS1,AFF1,MYO5A,P2RY1,GPR137C,PDE4B,EPN1,PPP3CA,PROX1,MARCH1,RAB3A,ATG16L1,RPRD1A,ATXN2,ATXN7,FNDC3A,DHX30,BTBD7,ATF7IP,ERC1,RAP1GAP2,LMO3,PLCB1,PCDHB15,ARHGEF12,GPRIN3,HHIP,RBFOX2,MTCH1,RICTOR,JMJD1C,NHSL1" MicroRNA hsa-miR-297:PITA hsa-miR-297:PITA_TOP PITA 3.29E-39 1.85E-35 9.12E-39 8.40E-38 75 234 "ACLY,SLC12A5,OSBPL8,MAP4K3,API5,NCOA1,EIF4G3,WASF1,LRBA,NRXN1,CREB5,ERC2,PLCXD3,CTNND2,SNAP91,MBNL2,EGR3,ELAVL4,SRRM1,SUCO,PSD2,GABRB3,NCKAP1,SESN1,GK,TCERG1,GRIA2,GRM1,INSM1,XRRA1,NEUROD1,NEUROD2,NRCAM,PCSK2,CDK14,PLP1,STRN3,LRP12,PPP2R5C,GDPD1,QRICH1,FAM120C,RNF220,CLIP1,SCN8A,HSPA4L,FHOD3,R3HDM2,CCDC88A,CAMTA2,NKAIN2,CAMTA1,ANO4,TCF4,TCF12,SYNE1,ARHGEF12,HHIP,CSMD1,KAT6B,TPM1,TRPS1,SSBP2,VLDLR,NSD2,XRCC4,ZIC2,ZBTB38,ZFAND5,SYNC,CA10,EMSY,CADM2,EVI5,KCNAB1" MicroRNA hsa-miR-1909:mirSVR_highEffct hsa-miR-1909:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.31E-39 1.86E-35 9.18E-39 8.46E-38 113 528 "EMILIN3,ADD1,ADD2,PTCHD1,ZNF687,AMPH,LCORL,GPAM,SPTBN4,ASPH,RGS9,CA4,DDR1,TRIM41,P2RX6,CD86,RCBTB2,CBARP,MS4A7,ZFYVE9,PPT2,SLC35F1,ANKRD44,CS,GPSM1,CYBB,PHF19,TOMM20,DAPK3,JAKMIP2,GSDME,PLPPR4,WDPCP,TSPAN5,KLHL5,GPHN,SRRM1,CDHR1,CLVS1,DLC1,FER,FGF1,FGFR1,BAIAP2,IP6K2,USP21,ARFGAP2,SDCBP2,GABRA3,JPH4,TMEM8B,NTNG2,STMN2,GRM2,ELOVL5,ITPKB,KCNC1,MAN2A2,MARK1,MEIS1,PABPC1L2A,FXYD6,NKX2-2,NOS1,P2RY1,PC,PDE1B,ZDHHC8,HERC2P3,SNX10,SMOX,SH3KBP1,KANSL1,MAPK4,SYTL2,PEX5,RAB5B,MYH14,FBXW7,KCNIP1,PEAR1,NTNG1,FHOD3,ST3GAL3,SLC9A5,TMEM132D,DMRTC1,IFT122,SNRPN,WDTC1,BEX1,ZC4H2,SULF2,SEPT3,NSFL1C,ABCC8,TBX15,PCDHAC2,ARHGAP9,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CRB1,AP4E1,R3HDM1,LRTM2,PITPNB,NPDC1,HNRNPA3,ADAMTS10" MicroRNA hsa-miR-223-3p:TargetScan hsa-miR-223-3p TargetScan 3.54E-39 1.99E-35 9.83E-39 9.05E-38 82 282 "ARID1A,PLEKHH1,PKP4,APC,MARCH3,NCOA1,ATP2B1,MTMR2,PTBP2,AIFM1,SCARB1,KMT2C,NRXN3,HDAC4,PHF19,RIMS3,DNAJC6,DOCK2,PHF20L1,ABI2,F3,ARMCX1,FOXO3,ANKFY1,CSPG5,BRPF3,COPS8,GLUL,KCNMB4,CNDP1,GPM6B,GPR22,KLF12,HLF,HNMT,RBPJ,KIAA1755,IL6ST,BRINP3,INPP5B,LMO2,GPR155,MAP4,MBNL1,MEF2C,MMP16,LAYN,NDP,NFIA,NOVA2,OPCML,PAX6,PDE3B,PDE4D,PDPK1,PFKFB3,PIK3C2A,NLE1,LRP12,PRKACB,CEP41,GTDC1,RORB,FBXW7,MCMBP,SCN2A,SCN3A,SCAF8,CPEB3,CLSTN1,ERC1,NFASC,FAM168A,PSD3,C18orf54,CBX5,HEY2,RFTN2,AGMO,LYPD6,KAT6A,NLRP3" MicroRNA hsa-miR-412:mirSVR_highEffct hsa-miR-412:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.27E-39 2.40E-35 1.18E-38 1.09E-37 132 703 "NCKAP5,XKR4,ADD1,CDC7,HECW2,KLHL13,PPFIA1,PKP4,SHTN1,SPTBN4,PDE8B,NCOA1,DPY19L3,TTLL9,BACH1,CFLAR,SYNJ2,KALRN,VSTM2A,SPAG9,TMEM257,CDH10,RAB28,CLU,QKI,ARMC8,SUMF2,LETMD1,ACBD5,MFSD4A,TRIM69,SNCAIP,ATRNL1,PNPLA8,CTH,CFAP61,KATNAL2,ARHGAP24,NTM,RABGAP1L,DNM1L,MBNL2,ELAVL3,MRNIP,STARD3NL,RABEPK,SRRM1,EPS8,FDFT1,FER,CAP2,SEMA4D,NOP56,STAG2,ZNF638,CBX1,POLL,GRIK2,FAM19A2,RNF165,MFSD2A,GUCY1B1,ZHX1,ZNF546,LIX1,KPNA5,STXBP5,ZFYVE27,MAT2A,MDM4,MEIS1,MRPL42,MTR,LYRM9,NAP1L2,NASP,NCAM1,ODF2,OGG1,GDAP1L1,A2ML1,TMEM38A,ING3,SEPT4,CEP41,PRKCZ,HYDIN,PTN,CEP97,GTDC1,ROBO1,RORB,ELP2,LRRK2,SOX6,SFPQ,ASRGL1,NLGN1,SLC1A3,SEPHS1,SORCS3,SMARCE1,PDZRN3,RBM34,WDTC1,KDM4C,NPAS3,TAB2,SSTR2,NKAIN2,SYNE2,KLHL4,TBX15,ATMIN,TPCN2,USP32P1,TEK,TF,DICER1-AS1,ITGB3BP,MTMR14,TMOD1,C5orf64,RFTN2,TST,UGT8,ZNF711,SIGLEC10,PCDH15,DNAH10,CASC15,CERS6" MicroRNA hsa-miR-940:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.60E-39 2.58E-35 1.27E-38 1.17E-37 133 713 "SDE2,ABCF1,AS3MT,NDRG3,RNF157,ADD2,PNMA8B,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ATM,ZNF583,BTRC,FOXK1,ZNF555,PTBP2,ISPD,SLC16A4,MYOM2,CFL2,KMT2C,NRXN3,LETMD1,MFSD4A,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,KIAA0513,PHYHIP,TMEM170A,ELMSAN1,SGSM2,SLC29A4,GNE,SYT15,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,TMEM151A,GABRB1,B4GALNT1,RAPGEF6,SESN1,GLUL,STARD3,ZNF638,FERMT2,GPR26,TUBA1C,ZNF496,KIF3A,BVES,IRAK3,AGBL5,ZNF546,C5orf24,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,NRGN,KSR2,NUCB1,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,ATXN1,IL17RB,SH3BP2,MYO18A,SHMT2,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,FAM168A,ZC3H4,CAMSAP2,FAM208A,USP22,PCDHA6,AHCYL2,ARL10,ERCC6L2,TPM3,TPM4,SSBP2,TUB,USP1,ZNF708,ZNF24,SNX27,MPPE1" MicroRNA hsa-miR-202:PITA hsa-miR-202:PITA_TOP PITA 4.68E-39 2.63E-35 1.29E-38 1.19E-37 73 222 "XKR4,CASKIN1,PCDH19,MRTFA,ZBTB10,BCL7A,SYNJ1,NIPA1,BSN,CACNA1E,FOXN3,CHN2,NDST3,MYRIP,SEC24C,ZC3H11A,CPEB2,DRP2,DUSP9,SEMA3D,YAF2,EFNB3,TENM1,ELAVL3,TMEM35A,STARD3NL,DLC1,IP6K2,GHR,PPARGC1A,TNRC6A,RNF165,HAS2,ARHGAP19,MIER3,NEGR1,SMAP1,KCNK3,KIF2A,MYCN,NAP1L1,GPR137C,PMP22,TRHDE,LRRN3,PKN2,LAMA1,UHRF1BP1,PTPRD,PTPRO,CPEB3,DZIP1,WDR47,CPEB4,SOX11,HECW1,KIF1B,TAB2,STAU1,SULF2,PRRC2C,SYN2,SYT1,TCF4,DICER1,CSMD1,RBFOX2,SLC30A4,ADAMTS9,SNX27,KAT6A,PHTF2,VANGL2" MicroRNA hsa-miR-1253:PITA hsa-miR-1253:PITA_TOP PITA 4.81E-39 2.70E-35 1.33E-38 1.23E-37 81 276 "ACLY,DSCAML1,SORCS1,LRRC7,MTMR9,SYNJ1,BTK,CACNA1E,FMNL3,CHN1,KMT2C,CLCN4,FRMPD4,ZFYVE16,ELMSAN1,DLG2,DLG4,SIDT2,EFNB3,EGR3,EPB41L1,UBE2E3,FOXO3,AHCYL1,JPH4,NEK6,CPLX2,GFRA2,TCERG1,EML4,GRB10,LINGO1,BACH2,LRRC75A,PLD5,KIF5A,MEIS1,MSI1,PABPC1L2A,NFIX,NPTX1,NTRK3,PBX1,PDE1C,OLA1,ANLN,PLP1,DRAM2,MED1,CEP41,PEX2,NKAIN1,RGS4,SETD5,ROBO2,FBXW7,RTN1,SCN8A,PPM1E,R3HDM2,NLGN1,WDR47,WDTC1,SOX11,NPAS3,TTBK2,SYT11,VAMP1,ANKRD28,CAMTA1,ADGRL3,ARHGEF12,RBFOX2,CADM1,NDRG4,TCEAL7,REEP1,SYNC,MAP3K12,TMEM178A,KAT6A" MicroRNA hsa-miR-644:mirSVR_highEffct hsa-miR-644:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.57E-39 3.69E-35 1.82E-38 1.68E-37 118 576 "NLGN4X,NR0B1,LRRC7,CARNS1,PKP4,FAM131A,APP,MIER1,MARCH3,DYNLL1,BCL2L2,BCS1L,DST,CAMK2B,CLDN10,LGI1,CHGB,NRXN3,SLC25A27,MYRIP,ZFP28,CNRIP1,SEC31B,ABCG1,MICAL2,UBXN2A,CTH,DCAF4,CX3CR1,HDAC9,KIAA0586,DLG2,DMTF1,DRD1,DNM1L,PHF20L1,SUGP2,EPB41L2,EPHB1,TMEM74,RTN3,RACK1,TOMM40L,KAT8,FGF1,FOXF2,SYNCRIP,FLNC,RASL10A,TMEM151A,GABRA5,NEK6,TUBGCP4,SRCAP,GLS,LUZP2,ZNF782,PRUNE2,HMGCL,TLX1,CFAP126,C2orf72,KCNC2,IPO5,PAXBP1,MAN2A2,MAT2A,MBD1,NCAM1,NEFH,NF1,DNHD1,NUCB2,GPR88,GLIPR1L2,PDE1C,PDE4D,GNG2,ZDHHC8,MINDY2,PPM1B,MAPK9,DIRAS2,PTPRO,RET,RFX4,SLC25A36,NUDT11,PBRM1,EXD2,KIRREL1,ROBO2,KCNIP1,SCN2A,FERMT1,SHMT2,CCDC92,URGCP,ZNF430,SLC8A3,BTBD7,CLUAP1,NFASC,FGD4,ZFR2,ASTN2,DDHD2,TCF4,TRIM2,WDR7,ERCC6L2,TPM1,TSN,BEST1,ZNF154,SEMA3B,RTN4,PHTF2" MicroRNA hsa-miR-532-5p:PITA hsa-miR-532-5p:PITA_TOP PITA 6.61E-39 3.71E-35 1.83E-38 1.68E-37 73 223 "SLITRK1,PWWP2A,ZNF608,ALS2,CACHD1,CAMK2G,SLC25A14,CAPN3,CAST,CDC42,DCLK1,ZMYM4,DLGAP2,CACNA2D2,FOXN3,ARMC8,SLITRK5,CTNND2,ELAVL2,ATP8A1,SEC24B,SUCO,UBE2E3,NBEA,CHL1,PCDH17,GRIA4,CIT,KLF12,NEGR1,NKD1,IBA57,CLVS2,IPO5,KTN1,MAP2,NDP,HCN1,GPR137C,PCDH9,PCSK1,PDE1C,OLA1,PIK3C2A,PURG,PTPRB,OXR1,RAVER2,ATXN1,PPM1E,CPEB3,CHD9,SLC8A1,BTBD7,CXXC4,PDZD2,LRRC4,ELOVL4,SYT11,VAMP1,SYN2,ANKRD28,TRIM2,WASHC4,RALYL,TLL2,ZFP91,RBFOX2,XPO1,PCDH20,LYPD6,PAK5,HNRNPA3" MicroRNA "GCAAAAA,MIR-129:MSigDB" "GCAAAAA,MIR-129:MSigDB" MSigDB 7.67E-39 4.31E-35 2.12E-38 1.95E-37 65 174 "ACTN1,XKR4,ZNF608,PHF12,APC,ZBTB10,EIF4G3,RUNX1T1,USP6,DLGAP2,NRXN2,NIPBL,SLC25A27,NRG2,ZNF385A,CTNND1,TOX,MATR3,ABCC5,YAF2,EPHB1,ETV1,CACNG2,ACSL4,TAOK3,PDLIM5,GFRA2,GLYR1,GRM7,RNF165,BACH2,HMGB1,HNRNPK,MEIS1,MEIS2,JAKMIP3,PAX6,PIK3R1,PDZRN4,ING3,SH3KBP1,PRKCB,PTPRZ1,OXR1,FIGN,FBXW7,SCN8A,SEC14L1,MYT1L,SOX2,SP4,NKAIN2,SYT1,CAMTA1,ADGRL3,PSD3,NR2C2,TRIO,FNDC5,PITPNB,TBC1D15,CELF4,PMEPA1,STOX2,SLC17A6" MicroRNA hsa-miR-518f:mirSVR_lowEffct hsa-miR-518f:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.76E-39 4.36E-35 2.14E-38 1.97E-37 120 595 "ACTN2,NDRG3,FMNL2,PLEKHG5,PSMG3-AS1,RNF150,OLMALINC,LRRC7,ALAD,CNTNAP1,AMER3,APP,ASGR1,FUBP1,THSD7A,KALRN,NGB,CANX,BRSK2,CCPG1,SRSF11,SOCS6,NRXN1,QKI,SULT4A1,MAP4K4,ARHGEF6,SLC25A27,COL9A1,SLC4A7,MYRIP,ZNF521,AKAP12,ANKRD44,GAPVD1,KCTD8,DAPK1,SIRPA,DGCR5,SRGAP3,DMPK,SLC29A4,CDON,EDN1,SGK2,BSCL2,EIF1,MRPL37,EXTL1,MED12L,IP6K2,NELFCD,SDCBP2,TUBA8,GFAP,PCLO,GRIA1,GRIK1,LINC00839,AGBL5,HSD17B1,LINC00667,SYTL4,MAP6,MOBP,MPP2,LYRM9,RTL5,NME4,NRGN,OPA1,BEST3,PFKFB2,SSH1,GRAMD1C,PTHLH,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,WLS,FOXRED2,SCN2B,SCN3A,HSPA4L,BCAN,SHANK2,CPEB4,IFT122,PDZRN3,SON,MYT1L,KDM3A,SEPT8,STAC2,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,ZMAT3,RIMBP2,C5orf64,TPM3,TRIO,TSC1,UCHL1,CELF4,ZFAND5,WNK1,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-95:mirSVR_lowEffct hsa-miR-95:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-38 5.73E-35 2.82E-38 2.59E-37 92 360 "CLK4,ARID1A,PWWP2A,WDR35,AMPD2,EP400,DGKD,ARRB1,SEC11C,DST,MYRF,CALM1,CANX,VSTM2A,CCPG1,SYNPR,JAM2,NRXN3,NIPBL,CNRIP1,AKAP12,PITPNM3,EDRF1,BOC,ARMCX2,ZEB2,WDR20,SEC16A,DMD,DMTF1,DNAJB6,DYRK1A,MBNL2,ZIC4,TESK2,AGAP3,PRELID3A,TBR1,MPP6,ZNF559,CYP46A1,MMADHC,TDRKH,EML4,GRIA1,GRM8,AP4S1,HAS2,TJAP1,LRRTM3,SLC35G1,KCND2,GLIPR1L2,PDE4A,HMGCLL1,MED1,SH3TC2,RASGRF2,RBBP8,KIAA0895L,TCP11L1,ATAT1,MIR124-2HG,ATXN2,LINC00461,ASIC4,ELMOD1,TRIM46,NAPB,DMRTC1,LIMCH1,SON,WDTC1,CLUAP1,ATP10B,ELOVL4,SLC19A3,PCDHA1,SIK3,SLC44A1,HEY1,AMACR,RUSC1,BCL2L13,NSD2,ZNF708,ZNF154,EMSY,EVI5,SCG2,PCDH15,NAV2" MicroRNA hsa-miR-525-5p:PITA hsa-miR-525-5p:PITA_TOP PITA 1.07E-38 6.01E-35 2.95E-38 2.72E-37 77 251 "FZD9,BSN,CAMK2A,CAMK2G,SEPT7,CDC42,DLGAP2,FOXN3,CLTB,RCHY1,SEC24C,CNTNAP2,ERC2,DCAF8,TOX,SV2A,TMCC2,DLG3,DMD,KMT5B,ELN,AGAP3,ATP6V1H,IQGAP2,GFRA2,CDH20,KCNMA1,SMAD1,MAP2,MEIS1,MEIS2,MID1,NDP,NFIX,NOVA1,SLC11A2,NUMA1,PDE1B,NLGN3,PIK3R1,ANKRD16,TNPO2,PPP2R5E,PSD,TMEM260,BSDC1,UBR7,RGS4,RNF220,SETD5,RTN1,SEMA6D,ATXN1,ATXN7,ZNF821,ASRGL1,SGK1,PPP4R3A,SLC8A1,SCN3B,FNBP1,EPB41L3,FBXW11,EHBP1,SATB2,RPGRIP1L,NSD1,PUM2,THRA,ZFP91,AMOT,CADM2,LRP8,PPP1R3F,SNX27,WIPF2,PAK5" MicroRNA hsa-miR-520a-5p:PITA hsa-miR-520a-5p:PITA_TOP PITA 1.07E-38 6.01E-35 2.95E-38 2.72E-37 77 251 "FZD9,BSN,CAMK2A,CAMK2G,SEPT7,CDC42,DLGAP2,FOXN3,CLTB,RCHY1,SEC24C,CNTNAP2,ERC2,DCAF8,TOX,SV2A,TMCC2,DLG3,DMD,KMT5B,ELN,AGAP3,ATP6V1H,IQGAP2,GFRA2,CDH20,KCNMA1,SMAD1,MAP2,MEIS1,MEIS2,MID1,NDP,NFIX,NOVA1,SLC11A2,NUMA1,PDE1B,NLGN3,PIK3R1,ANKRD16,TNPO2,PPP2R5E,PSD,TMEM260,BSDC1,UBR7,RGS4,RNF220,SETD5,RTN1,SEMA6D,ATXN1,ATXN7,ZNF821,ASRGL1,SGK1,PPP4R3A,SLC8A1,SCN3B,FNBP1,EPB41L3,FBXW11,EHBP1,SATB2,RPGRIP1L,NSD1,PUM2,THRA,ZFP91,AMOT,CADM2,LRP8,PPP1R3F,SNX27,WIPF2,PAK5" MicroRNA hsa-miR-489-3p:TargetScan hsa-miR-489-3p TargetScan 1.09E-38 6.13E-35 3.01E-38 2.77E-37 74 231 "KLHL32,ADCYAP1R1,CDC7,PKP4,DST,CACNA1D,LURAP1,CALM1,LONRF2,CDH8,RAB3C,NRXN3,NIPBL,CLOCK,KATNAL2,MATR3,DCC,DNAJC6,JAKMIP2,MTX3,DLX1,FEM1B,ELAVL4,IGSF6,EYA1,MRVI1,CACNG3,GNAL,GPR22,GRIA4,GRIK2,PRDM5,GUCY1A2,HAS2,FRMD3,HPSE2,C5orf24,KCND3,CLVS2,KCNN2,IPO5,PACRG,MMP16,DBNL,HS6ST3,MXI1,NOVA2,OPCML,PAK3,PAX6,PDE1B,CEP41,MAPK8,PROX1,PEX2,RAB3A,RORB,FBXW7,GLDN,CSRNP3,SCN2A,FNIP1,PPP1R9A,CPEB3,MAGI3,CHD9,HECW1,MYCBP2,LRRC4,NACC2,CBX5,C5orf64,CADM2,FZD3" MicroRNA "ATACTGT,MIR-144:MSigDB" "ATACTGT,MIR-144:MSigDB" MSigDB 1.15E-38 6.45E-35 3.17E-38 2.92E-37 68 193 "ARID1A,SEMA6A,ANK2,ALS2,CACHD1,ATP2B1,ATP2B2,NRP2,CDH2,LHX2,QKI,PPP1R16B,PUM1,ST18,RHOBTB1,SNAP91,DMD,CPEB2,RBM12,EIF4G2,EIF5,CALCRL,EPB41,ACSL4,ZIC4,FOXG1,ST6GALNAC3,GCNT2,CBX1,NR3C1,WIF1,BACH2,HSF2,LIFR,NCOA7,MEIS1,MEIS2,MSI1,MYT1,NFE2L2,PDE4D,PFKFB2,PCDH18,PPARA,PTHLH,RFX4,RIC8B,LGR4,SEMA6D,ATXN1,SMPD3,CPEB3,FNDC3A,CCDC88A,SLC12A2,SORCS3,SON,SP4,CDK19,SS18,FBXW11,RPGRIP1L,TRIO,FMN2,NAV3,KAT6A,PHTF2,SENP7" MicroRNA hsa-miR-634:PITA hsa-miR-634:PITA_TOP PITA 1.18E-38 6.60E-35 3.23E-38 2.98E-37 80 272 "SLITRK1,SNX30,ESYT2,ADRB2,OGT,APP,SLC4A4,ATP2A2,DCAF5,CAMK2A,CAMK2G,NRXN3,KIAA1549L,CREB5,RGS6,LRIG1,OSBPL3,LONRF1,GIT2,ALKBH8,RHOBTB1,SRGAP3,G3BP2,DLG2,ABI1,PDCD6IP,DYRK1A,ABCC5,YAF2,ELAVL2,PLEKHA1,PAN3,EPB41L1,ERBB4,AFF2,SYT3,LOXL3,GPD2,CELF3,HMGCR,KCNK2,KCNMA1,NEUROD1,XRN1,LRP12,EPB41L4B,FAT3,MED1,RASGEF1B,CNTLN,TMEM255A,SETD5,FBXW7,RTN1,SEMA6D,CPEB3,CNKSR2,PPP4R3A,BTBD3,SMTN,SLC8A1,CPEB4,RIMS1,PALLD,SOX11,LMO3,CLASP2,ERBIN,GSE1,ADGRL3,TCF4,PSD3,RBFOX2,TSC1,FAM155A,TBC1D15,SYNC,PRDM2,NAV3,DPF3" MicroRNA hsa-miR-643:PITA hsa-miR-643:PITA_TOP PITA 1.31E-38 7.37E-35 3.61E-38 3.33E-37 73 225 "CCDC85A,NLGN4X,GPR158,HECW2,BCAR3,ANK3,LCORL,GAS7,API5,ARNTL,USP6,NUMBL,RAB33A,NIPBL,CNR1,IGDCC3,PHACTR3,ST18,GAPVD1,TOX,LONRF1,DDX46,USP3,DPYSL2,ABI1,EBF1,HIPK3,YAF2,SH3GLB1,MBNL2,ERBB4,CLVS1,WAC,ZIC4,STAG2,SPIN1,RAB30,GRID1,GRM1,FAM19A2,PSIP1,HMGB1,NEGR1,MAP2,MEIS1,OPCML,CLDN11,PLP1,LRP12,SCHIP1,DIRAS2,TTC13,RORB,SCN3A,FAM19A1,FNIP1,WDR47,TET1,NEK4,FAM208A,SATB2,TRIM2,TCF12,DOCK9,AHCYL2,AP4E1,ZNF106,SLC44A1,KAT6B,TPD52L2,SYNC,SLC38A1,MSRB3" MicroRNA hsa-miR-609:mirSVR_highEffct hsa-miR-609:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-38 8.65E-35 4.24E-38 3.90E-37 102 442 "ACLY,ARID1A,SORCS1,BEND6,LCNL1,GPR158,LGR5,SEMA4G,TMEM263,ATP1A1,N4BP2L1,CARMIL3,ARHGEF7,MTMR2,CCKBR,CBFA2T2,LRBA,ZMYM4,NDST3,NRXN2,TJP2,IGLON5,ABI3BP,CYBB,GPRASP1,ARHGAP32,DNAJC6,DMD,DNM1L,AASS,DCTN4,OLIG2,GPHN,MRVI1,F5,CLVS1,SLC9B2,SPECC1,UFM1,USP21,FYB1,AHDC1,GGTA1P,GNAO1,GRIK2,FAM19A2,ZBTB49,GUCY1A1,RASSF8,HPS5,HNRNPK,TJAP1,PLD5,OLFM3,MAN2A2,NF1,OGG1,PDPK1,CDK14,MTRF1L,PKIA,HYDIN,DIRAS2,MDGA2,PTK2,TMEM145,SLC25A48,BSDC1,RFX4,KCNIP1,ZNF568,SCP2,ITSN1,CTXN2,CCDC88A,SMARCE1,SNRPN,TMCC1,PDZRN3,HECW1,ATP10B,SYT11,MTCL1,DMXL2,FRYL,SIRT1,AKTIP,FAM124A,TPD52,IL34,AMACR,GORASP1,VAV1,BEST1,ZIC2,PLPPR5,GOPC,CASC15,ADAMTSL3,ZNF248,SSPN,CBLN2" MicroRNA hsa-miR-10b:mirSVR_highEffct hsa-miR-10b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.60E-38 8.96E-35 4.39E-38 4.04E-37 116 563 "KIAA1211,ALCAM,LTBP4,CCDC146,UPRT,IGDCC4,DOCK11,SGCE,NFS1,CLTA,CNTFR,CNTN1,ABI3BP,SLC35F1,NCOR2,RIMS2,GAPVD1,HP1BP3,KIAA0753,CEP170,DDX46,DSCAM,E2F5,EDN3,FCF1,YAF2,PHF20L1,EGFR,ELAVL2,EIF1,EPHA5,SCML2,RACK1,CEP78,CAP2,UFM1,GAD1,ZMYND11,NEK6,GART,GLS,RAPGEF4,C1QL4,GRIK1,RNF165,ZHX1,HMGCR,SMAP1,IGSF1,KCNA6,KCNK2,KLC1,LIMS1,ARHGAP12,EFHB,AFDN,MYO9A,CNOT4,HCN1,SLC10A4,XRN1,FAM216A,HMGCLL1,PURG,LRP12,EPB41L4B,POU3F2,TATDN3,PPP3CB,RAB39A,VPS13C,MDGA2,ELOVL2,ZYG11B,ERI2,FIGN,RPRD1A,TMEM206,RPE,STK32B,SCP2,SEC14L1,ZFP30,ITSN1,CCDC88A,SLCO1A2,SPHKAP,ZNF667,SON,PDZD2,SOX1,DOK5,NPAS3,POGZ,NXT2,PRRC2C,TRIM2,SYNE1,PUM2,FAM200B,TIAM1,DCBLD1,CADM1,SLAIN1,ZIC3,LYPD6,ZNF154,FSTL5,ZNF189,PLPPR5,SYNC,SLC30A4,NAV3,WNK3,MVB12B,PDSS2" MicroRNA "ACTTTAT,MIR-142-5P:MSigDB" "ACTTTAT,MIR-142-5P:MSigDB" MSigDB 2.12E-38 1.19E-34 5.83E-38 5.37E-37 80 274 "RALGAPA1,ALCAM,GAS7,ALS2,SLC4A4,ATP2B1,ADGRB3,SYNJ1,CAMK2A,TAOK2,CLCN3,QKI,SLC25A27,C2CD2,FAM131B,SPOCK2,C8orf34,SACS,FAM107B,CPEB2,EGR3,ELAVL2,ELAVL4,ETV1,MED12L,FGF13,SORBS1,BRPF3,LUZP2,GRM7,RNF165,BVES,IGF1,KCNJ3,KIT,LRP1B,KITLG,MKLN1,MYCN,NFE2L2,NTRK3,GPR88,ZFYVE21,RETREG1,HMGCLL1,LRP12,RETREG2,SLC22A23,CEP97,ATG16L1,RBBP8,REV3L,FIGN,RIC8B,RNH1,ROBO1,RTN1,FAM19A1,CPEB3,CHD9,FNDC3A,ARHGEF40,SHANK2,BTBD7,CPEB4,MBD5,SON,SOX5,SP2,CAMTA1,ADGRL3,TCF12,ZFPM2,DDHD1,RGMA,SLC17A7,GOPC,JMJD1C,NETO2,ST8SIA2" MicroRNA "CAGCTTT,MIR-320:MSigDB" "CAGCTTT,MIR-320:MSigDB" MSigDB 2.37E-38 1.33E-34 6.51E-38 6.00E-37 75 240 "UNC5A,PCDH19,OGT,LRCH2,MIER1,CDK13,TMEM108,CACNA1E,TRIM41,CDH2,FOXN3,QKI,CREB5,PPP1R16B,HDAC4,DBN1,ARMCX2,RHOBTB1,CALN1,DSCAM,KMT5B,PLXNC1,PAN3,NSRP1,MEX3B,FAM49B,STAG2,CAB39,DNER,PPARGC1A,NEGR1,SMAP1,ICA1,CDH20,HECTD2,MAT2A,MMP16,MN1,MXI1,PPM1B,PPP2R2C,TMEM255A,SEMA6D,ATXN1,FBXO11,SLITRK3,BTBD3,DHX30,PALLD,SON,LMO3,TROVE2,POGZ,NCDN,MAPK8IP3,TAC3,CAMTA1,CAMSAP2,SATB2,CLASP1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFP91,TPD52L2,TPM3,TSC1,NSD2,XPO1,ZIC3,PAK5" MicroRNA hsa-miR-4304:mirSVR_lowEffct hsa-miR-4304:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.51E-38 1.41E-34 6.89E-38 6.34E-37 106 478 "ASPHD1,KLHL32,CCDC85A,ERMN,KIAA1211,ADRB2,CASKIN1,TBC1D14,CADPS,CDK13,NCOA1,ATP1B3,CACNB4,BRSK2,LDB2,CHN1,NDST3,NRXN3,FAM19A5,MAP4K4,RTTN,CREM,NCOR1,SNCAIP,CSF1,ARHGEF10,CSNK1G3,GREB1,ARHGAP24,ALKBH8,DTNA,EIF4G2,KIAA1109,OLFM1,FHL1,FOXG1,USP16,NRG3,ZMYND11,PPARGC1A,GK,RAPGEF4,NR3C1,ELOVL5,GABARAPL2,C2orf72,LRRC25,ZIC5,SCIN,ITPKA,KCNC1,KCNK1,KCNMA1,STXBP5,LIFR,LIMS1,VWA5A,MEIS2,CPNE9,MXI1,IDNK,NEK1,SLCO1C1,IGSF11,P2RX7,PKD1,GPSM2,PURG,SCHIP1,SEPT4,MBOAT7,KANSL1,QRICH1,PTCH1,PTHLH,USP47,TTLL7,CLIP1,AP1AR,SCN7A,SCN8A,BTBD7,SPHKAP,RIMS1,SNRPN,SON,UHRF1BP1L,KDM4C,ERC1,EPB41L3,NKAIN2,NXT2,MAPK8IP3,DIP2A,KLHL7,KAZN,ERCC6L2,HEY2,TPM1,UGT8,MEAF6,XPO1,XRCC4,MKRN3,CELF4,PHTF2" MicroRNA hsa-miR-199a-3p:TargetScan hsa-miR-199a-3p TargetScan 2.54E-38 1.43E-34 6.97E-38 6.42E-37 91 356 "ADD3,PLEKHH1,KCTD16,HACE1,BCAR3,ARHGAP20,CNIH2,NCOA1,ASTN1,CDK5R1,FUBP1,ARHGEF2,REPS2,CFL2,QKI,ARMC8,COL4A5,RNF14,ANKRD44,CCDC144A,LIN54,KLHL3,G3BP2,DTNA,EBF1,HIPK3,FRY,ELAVL2,ERBB4,CEP85L,MED12L,PSD2,FAM49B,CELF1,FUT9,HHIPL1,PHYHIPL,IQGAP2,GCNT2,PCDH17,GNAS,LPAR4,EML4,CECR2,RAPGEF4,KLF12,HNMT,CELF5,IGF1,KTN1,MBNL1,MEF2C,MEIS2,MMP16,NAP1L1,NFIA,NOVA1,DDR2,PDE4B,PDGFRA,PURG,FAT3,PPM1B,PPP2R5E,MAPK8,MDGA2,PTPRG,PTPRZ1,FIGN,RFX3,RORB,PPP1R9A,CCDC88A,ATF7IP,CPEB4,KDM4B,KDM3A,EMC1,LMO3,PLCB1,FBXW11,ARHGEF12,NACC2,DDHD1,NAV3,PCBP4,MVB12B,ADAMTSL3,FXR1,DPF3,GAN" MicroRNA hsa-miR-199b-3p:TargetScan hsa-miR-199b-3p TargetScan 2.54E-38 1.43E-34 6.97E-38 6.42E-37 91 356 "ADD3,PLEKHH1,KCTD16,HACE1,BCAR3,ARHGAP20,CNIH2,NCOA1,ASTN1,CDK5R1,FUBP1,ARHGEF2,REPS2,CFL2,QKI,ARMC8,COL4A5,RNF14,ANKRD44,CCDC144A,LIN54,KLHL3,G3BP2,DTNA,EBF1,HIPK3,FRY,ELAVL2,ERBB4,CEP85L,MED12L,PSD2,FAM49B,CELF1,FUT9,HHIPL1,PHYHIPL,IQGAP2,GCNT2,PCDH17,GNAS,LPAR4,EML4,CECR2,RAPGEF4,KLF12,HNMT,CELF5,IGF1,KTN1,MBNL1,MEF2C,MEIS2,MMP16,NAP1L1,NFIA,NOVA1,DDR2,PDE4B,PDGFRA,PURG,FAT3,PPM1B,PPP2R5E,MAPK8,MDGA2,PTPRG,PTPRZ1,FIGN,RFX3,RORB,PPP1R9A,CCDC88A,ATF7IP,CPEB4,KDM4B,KDM3A,EMC1,LMO3,PLCB1,FBXW11,ARHGEF12,NACC2,DDHD1,NAV3,PCBP4,MVB12B,ADAMTSL3,FXR1,DPF3,GAN" MicroRNA hsa-miR-3199:mirSVR_highEffct hsa-miR-3199:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-38 1.54E-34 7.53E-38 6.93E-37 107 487 "VWA5B2,SLC12A5,USP35,DPP10,USP37,PPP4R4,ARHGEF7,HAP1,CERS5,USP6,AP4M1,L3MBTL4,CASC2,TAOK2,EPS15L1,CLCN3,STOML1,RAB26,CNGA3,CNTFR,LETMD1,TBPL1,NECTIN3,FEZ1,CST3,PHF14,EDRF1,CCDC144A,RIPOR2,HEPH,FBXO25,ACOT8,ARRDC4,TOM1,SORBS3,VPS13B,RCAN2,CEP85L,CHST15,TOMM40L,ZNF589,NELFCD,ATP2C1,FYB1,SRCAP,GHR,GLI2,EML4,PCLO,C1QL4,ZBTB49,MAEL,SYNPO,FAM95B1,LRRCC1,ZNF678,A1BG-AS1,MAP4,MARK1,MBNL1,MPP2,COMMD5,MSRA,PDCD2,PDE3B,PFKFB2,A2ML1,HYDIN,PROX1,ZSCAN2,RFX2,RGS3,ATAT1,SCN2A,PAAF1,SLC1A7,PPP4R3A,EPN2,SLC8A1,SORCS3,SMARCD3,ANKRD36,SP4,HECW1,NPAS3,SRPK2,CLASP2,ST5,SULF2,SEPT3,VPS13A,TAC1,KIAA1107,SATB2,WDR7,FRYL,HIF3A,MTMR14,TPM3,CADM1,SF1,FMN2,EML6,LRP8,SNX27,PIANP,DPF3" MicroRNA hsa-miR-601:mirSVR_highEffct hsa-miR-601:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.89E-38 1.62E-34 7.92E-38 7.30E-37 94 380 "TMEM132B,SYT13,OGT,ANK2,PPFIA1,SFMBT2,ARNTL,CARMIL3,BCL2L2,RAB29,CBFA2T2,SYNGR3,DGKI,LRBA,CDH18,FAM19A5,CNTN1,SLC4A8,AHCTF1,ACBD5,CSF1,USP3,ECM2,DYRK1A,TENM1,CDHR1,F5,TUBB4A,FGF14,NRG3,TUBGCP4,SRCAP,PPARGC1A,TOX3,GLUL,KDM2B,GRM3,MIER3,HSP90AA1,SMAP1,IDH3B,LRRCC1,NME9,JAK1,KTN1,INSYN2,SYTL4,ARHGAP12,MYT1,SMIM11A,PBX1,CAMKV,CCSER2,NLE1,PRKACB,HYDIN,SNRK,ANKHD1,TMEM260,RAD52,SLC25A36,MCMBP,CSRNP3,IL17RB,SH3BGR,R3HDM2,CNKSR2,NLGN1,ANKRD6,SLC15A2,RCOR3,SNRPN,TROVE2,DNAJC9,DDHD2,FAM208A,ADGRL3,WDR7,SIRT1,TPM3,METTL3,RUSC1,HEPACAM,UGT8,RICTOR,FMN2,ZBTB38,EML6,ANKS1B,CSDE1,PRDM10,ADAMTS9,PAK5,FAM198A" MicroRNA hsa-miR-219-5p:mirSVR_highEffct hsa-miR-219-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.06E-38 1.72E-34 8.39E-38 7.72E-37 106 479 "CPNE2,KCNH8,ADD2,RTL9,MRTFA,PPFIA1,LGR5,SEMA4G,PLA2G4C,NCOA1,RNF182,N4BP2L1,NOL4,ADGRB3,CACNA1E,KALRN,INA,LRBA,LGI1,AKAP6,COL9A1,TOGARAM2,CNRIP1,CP,GREB1,DNAJC6,DDX46,RHOBTB1,CDON,TOM1,KLHL5,EGR3,PAN3,EYA1,ZSCAN30,SLC9B2,HPCAL4,FLT1,ILDR2,GAD2,TUBGCP4,PPARGC1A,TTBK1,GNAS,GRIK2,MIER3,KTN1,PACRG,SCG3,MYO7A,NME4,DNHD1,OCRL,ZNF827,PDGFRA,PURG,PDZRN4,TRHDE,ING3,RAB39A,VPS13C,SNRK,STK32A,PTPRG,MORC4,SETD5,RORB,ELP2,MCMBP,SATB1,SCN7A,LINC00461,HSPA4L,FERMT1,NTNG1,ST3GAL3,ANKRD6,ZNF365,TET1,SORCS3,RIMS1,SOX5,SP4,MCF2L2,SRPK2,TAB2,NUDT10,SYT4,SYT5,MMS19,ADGRL3,ACSL6,SATB2,TGFBR3,TIAM1,TPM1,UBE3A,PLEKHH2,VLDLR,BEST1,NDRG4,SLC30A4,PCDH15,C12orf4,SSPN,SLC4A10" MicroRNA hsa-miR-6808-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-38 1.72E-34 8.39E-38 7.72E-37 127 668 "SDE2,ABCF1,AS3MT,NDRG3,RNF157,ADD2,PNMA8B,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ATM,ZNF583,BTRC,FOXK1,ZNF555,PTBP2,ISPD,SLC16A4,MYOM2,CFL2,NRXN3,LETMD1,MFSD4A,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,KIAA0513,PHYHIP,TMEM170A,ELMSAN1,SGSM2,SLC29A4,GNE,SYT15,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,TMEM151A,GABRB1,B4GALNT1,SESN1,GLUL,STARD3,ZNF638,FERMT2,GPR26,ZNF496,KIF3A,BVES,IRAK3,AGBL5,ZNF546,C5orf24,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,NRGN,NUCB1,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,ATXN1,IL17RB,SH3BP2,MYO18A,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,FAM168A,ZC3H4,CAMSAP2,FAM208A,USP22,PCDHA6,AHCYL2,ARL10,ERCC6L2,TPM3,TPM4,SSBP2,USP1,BCL2L13,ZNF708,SNX27,MPPE1" MicroRNA hsa-miR-211-5p:Functional MTI Functional MTI miRTarbase 3.22E-38 1.81E-34 8.82E-38 8.13E-37 88 334 "AS3MT,XKR4,ADCY5,ADCYAP1R1,ADORA3,MTA3,SORCS2,AK2,SPOP,CACHD1,SEMA4G,ARSE,ASGR1,BCL7A,BID,MYRF,LURAP1,CAMK2G,SYT6,CDH8,SLC22A6,DNAJB5,SEC31B,CREB5,CHD5,PLCXD3,ELMSAN1,G3BP2,CHRDL1,FEM1B,SLC43A2,SRARP,AMOTL2,ANKFY1,FAXC,SRCAP,TPPP,NR3C1,PTPRT,PADI2,GPR45,BACH2,MIER3,HMX1,EID2B,KCNMA1,LSAMP,MBNL1,MDFI,XRRA1,SAMD5,MX1,NPTX1,PDE3A,PHKG1,POU3F2,KANSL1,MARCH1,RAB5B,CEP97,ZYG11B,DPF2,GTDC1,RORB,ELP2,TMEM156,ATXN1,ATXN7,ASIC4,GALNT10,MYO18A,BCAN,LRRC55,ZCCHC24,CLUAP1,ZBTB43,SMOC1,LRRC4,IQCE,SATB2,TCF7L2,TCF12,SEZ6L,TMEFF2,PRDM2,ZDHHC20,DPF3,GAN" MicroRNA hsa-miR-346:mirSVR_highEffct hsa-miR-346:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.55E-38 1.99E-34 9.70E-38 8.94E-37 98 413 "ADD2,PWWP2A,KIAA1211,INTS2,GOLGA7B,SUGT1P4-STRA6LP-CCDC180,PKP4,UPRT,FAM131A,LRRC4C,LGR5,ATP1A2,CADM3,CACNB2,SPAG9,MYOM2,TIGD7,JAM2,DGCR9,WHRN,SUMF2,SMARCAL1,RBM39,SNCAIP,PDE4DIP,RIMS2,ZNF337,DGKB,IP6K1,MYEF2,NTM,SGSM2,EXOG,FARSB,ABCC9,EXTL1,CHST15,TOMM40L,PRKAG2,IP6K3,ATP8A2,ALDH1L1,GRM7,PTPN5,AP4S1,ZNF491,IRF8,ITPKB,LAMP2,NCOA7,MBNL1,SYT9,KCTD6,ERICH3,THYN1,MYO9A,NF1,ALDH1L2,CLDN11,GPR173,SNX10,XRN1,MAPKAP1,SEPT4,NXPH1,PKIA,MDGA2,CNTLN,ZIK1,ZNF615,RDX,RGS4,RNASEL,RPRD1A,NEK11,KCNIP1,SORCS3,KDM4C,ZNF423,KIF1B,RBM26,ZC4H2,ERBIN,ADHFE1,ANO4,USP32P1,RGMB,TRIO,EIF4ENIF1,AMOT,CCDC136,SF1,ZNF177,PCBP1-AS1,PLSCR4,HRASLS,CASC15,ZNF248" MicroRNA "ATATGCA,MIR-448:MSigDB" "ATATGCA,MIR-448:MSigDB" MSigDB 4.72E-38 2.65E-34 1.29E-37 1.19E-36 69 203 "ADD1,UNC5A,HECW2,DOC2A,ANK2,APBB2,ARNTL,PCDHGB4,RNF182,DCAF5,USP6,ARMC8,SOCS5,DAPK1,BRINP1,CPEB2,KLHL5,MBNL2,KCNMB2,GPHN,ETV1,AFF2,NBEA,KBTBD12,GABRB3,GPM6A,GRIK2,BACH2,KCNB1,HECTD2,MEF2C,MYH3,PCDHGC3,PCDH8,PCDH9,KCTD15,ING3,SH3KBP1,PRKAB2,CEP97,ZFHX4,RAVER2,RORB,SH3GL2,NLGN1,SOX11,CDK19,SS18,SYN2,ATP11A,FBXW11,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,DOCK9,SIRT1,VLDLR,RICTOR,GAN" MicroRNA hsa-miR-600:PITA hsa-miR-600:PITA_TOP PITA 4.84E-38 2.72E-34 1.32E-37 1.22E-36 76 249 "GPR158,KLHL13,ALCAM,ANK1,MAP4K3,APBB2,NOL4,SYNJ1,PTBP2,CCK,FMNL3,INA,DLGAP2,CCPG1,EPS15L1,SLITRK5,ZNF804A,MYEF2,MAGI2,DNM2,DYRK1A,KCTD3,ELAVL3,DLC1,FOXG1,AFF2,NBEA,NPTN,C15orf41,ARFIP1,SPIN1,FERMT2,GRIA4,TOX2,NEGR1,IGFBP1,KCND2,STMN1,MAT2A,MSI1,MYO5A,RTL5,ZC3H12B,NOVA1,PCDH8,RETREG1,PPARA,PPP3CA,DIRAS2,PTPRD,ROBO2,TNFRSF19,PPP1R9A,NTNG1,MYT1L,SRPK2,ITPRID2,ST5,SYPL1,EHBP1,TCF4,TCF12,SZT2,TNS1,NR2C2,TRPC1,SGK3,UBE3A,UBTF,UCHL1,EMSY,STOX2,KAT6A,PHTF2,ST8SIA2,SLC4A10" MicroRNA hsa-miR-185-5p:Functional MTI Functional MTI miRTarbase 5.27E-38 2.96E-34 1.44E-37 1.33E-36 91 359 "DPF1,ARID1A,ADD2,CASKIN1,HACE1,TAOK1,PDZD4,KIF6,CACHD1,SFMBT2,IGDCC4,BACH1,CAMK2D,CANX,SCARB1,CDC42,EPS15L1,ARHGEF6,ZNF385A,CSF1,MICAL2,CSNK1E,CNTNAP2,SLITRK5,FRMPD4,TM9SF4,MATR3,IP6K1,SPATA2,ZC3H11A,SMG7,CHRDL1,ABCC5,E2F6,ELAVL3,CORO2B,FGFR1,AMOTL2,AFF2,CAMKK2,CELF1,DENND2A,SRCAP,TNRC6A,MSL3,GLUL,RAPGEF1,KAT7,HSP90AA1,SLC6A17,ZFYVE27,KITLG,C10orf105,PABPC1L2A,ZC3H12B,NEUROD1,NTRK3,GPR137C,PDE4A,PDPK1,PFKFB3,CDK14,PKD1,PKM,PLCD1,PTPA,ANKHD1,RAB5B,PLEKHB2,PRRT2,MORC4,MYH14,HSD11B1L,MRAS,BTBD3,PKNOX2,SLC8A1,CCDC88A,WDTC1,IQSEC2,ARC,SMG6,AHCYL2,HHIP,TMEM9,TMPRSS5,CADM1,SF1,SLC38A1,SIGLEC10,ITM2C" MicroRNA hsa-miR-578:PITA hsa-miR-578:PITA_TOP PITA 6.90E-38 3.87E-34 1.88E-37 1.73E-36 88 337 "KCNH8,ADD3,PCDH19,SPOP,LRCH2,ANK3,AQP4,CDC14B,RGS20,NCOA1,NUMB,DDX3Y,CAMK2G,RUNX1T1,LDB2,CLCN3,NIPBL,CNR1,BAG4,CREB5,KCTD8,ALKBH8,DLG2,DMD,ABI1,HIPK3,ELAVL3,RCAN2,EPHB1,MRVI1,ACSL4,FGF12,FLT1,TACC2,STAG2,ARFIP1,SESN1,PCDH17,PPARGC1A,GPM6A,LPAR4,GRIA2,GRID1,CIT,KCNK2,STXBP5,MEF2C,MEIS2,MITF,AFF1,MXI1,NF1,NPTX1,ZNF827,CDK14,RETREG1,PLP1,PKN2,PID1,TMEM255A,ARID4A,RDX,SETD5,RORB,ATXN1,ITSN1,PPM1E,TRIM67,CPEB4,SON,SOX2,HECW1,RGL1,SYPL1,VWC2,TCF4,DOCK9,AHCYL2,CSMD1,TNS1,TRPS1,SGK3,FLRT2,ZFAND5,SLC38A1,SLC17A6,PDSS2,MSRB3" MicroRNA hsa-miR-451:mirSVR_lowEffct hsa-miR-451:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 7.00E-38 3.93E-34 1.91E-37 1.76E-36 92 368 "PSMG3-AS1,SEMA6A,CACHD1,BCAS1,TNRC6C,DDX3Y,WASF1,CALM1,CBLN1,CBR1,P2RX6,SCARB1,TIGD7,MYRIP,PREPL,ARHGEF10,SIPA1L1,PDE4DIP,SDC3,EDRF1,MATR3,MAML1,IST1,GIT2,DNAL1,YTHDC1,C8orf34,SNAP91,SPOCK3,DMD,ATN1,SEMA3D,PHF20L1,EVL,WDR83,DLL3,ZMAT1,SALL3,NCKAP1,GCNT2,TOX3,LUZP2,STMN2,BACH2,LRRC75A,SOWAHA,KIAA1755,IL6R,KCNA4,KCNK1,KCNMA1,KIF2A,KTN1,LSS,RSPO2,NDUFA5,NF1,OXTR,ENPP2,SERPINE2,ING3,FA2H,MINDY2,PPP2R5C,TMEM231,FAM184A,RPRD1A,CLIP1,DOCK10,SLCO1A2,NPAS3,STOX1,LARP4,MPRIP,PLCB1,ASTN2,WWC1,SATB2,TCF7,ITGB3BP,AP4E1,SLC44A1,TPM3,TSC1,UBE3A,KLC2,XPO1,ANKS1B,UPF3A,DHX33,GAL3ST3,NHSL1" MicroRNA hsa-miR-140-3p.2:TargetScan hsa-miR-140-3p.2 TargetScan 8.08E-38 4.54E-34 2.20E-37 2.03E-36 90 353 "CDC7,PTCHD1,AP2A2,GPR158,PCDH10,ANK2,PHF12,LRRC4C,CCAR2,ATP2A2,ATP2B2,BSN,LDLRAD4,RUNX1T1,CDH18,FHL5,HS3ST5,NSL1,NCAN,PITPNM3,PYGO1,HDAC4,DGKG,IP6K1,DNM1,DRP2,HIPK3,CELSR3,PLXNC1,ELAVL2,EN2,RTN3,MED12L,FGF12,HPCAL4,FOXG1,KHDRBS3,CELF1,NRG3,GAB1,CHL1,GAD2,AHDC1,PCDH17,RAB30,GLUL,GPR12,GRM2,KAT7,MIER3,HLF,KCNB1,KIF2A,KIF5A,CHIC1,MEIS2,KCTD6,MMP16,FXYD6,NFYA,NNAT,NOVA1,PCDH8,PDE3A,OLA1,SCHIP1,PACSIN1,KANSL1,RASGEF1B,PROX1,PTCH1,KHDRBS2,ARMC5,ROBO2,FBXW7,SCN3A,FAM19A1,ATF7IP,DDN,NKAIN2,SATB2,DOCK9,AHCYL2,RBFOX2,RUSC1,GDPD5,MVB12B,GOPC,HNRNPA3,GAN" MicroRNA hsa-miR-489:PITA hsa-miR-489:PITA_TOP PITA 8.14E-38 4.57E-34 2.22E-37 2.04E-36 67 192 "XKR4,CCDC85A,ADD3,KLHL13,PCDH19,TAOK1,LRRC7,SEMA6A,NCOA1,ATP1B3,ATP2B1,ATP2B2,CACNA1D,LURAP1,CLOCK,SEC24C,DNAJC6,MAGI2,G3BP2,GRIN3A,NYAP1,FRY,PCOLCE2,TMEM35A,EMX2,EYA1,CACNG3,CELF1,FUT9,GABRB3,SPIN1,ATF7,SERP2,MIER3,C5orf24,KCNN2,IPO5,PACRG,MAT2A,MITF,HS6ST3,MXI1,MYO5A,NTRK3,PDE1B,PIK3R1,MED1,CEP41,TMEM260,RAP1GDS1,GLDN,SCN2A,PPP1R9A,PPM1E,SHC4,MAGI3,ST3GAL3,CPEB4,SMARCA4,FAM126B,SRPK2,LRRC4,SYP,DICER1,ZMYND8,CADM2,PAK5" MicroRNA hsa-miR-371-3p:mirSVR_lowEffct hsa-miR-371-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.21E-38 4.61E-34 2.24E-37 2.06E-36 102 450 "NCKAP5,KLHL32,PSMG3-AS1,KIAA1211,OGT,USP37,CDK10,CDK13,CAPRIN2,ATM,DPY19L3,ADGRB2,NRP2,AP1M1,PTBP2,TRIM41,SLC25A14,SEPT7,MAGI1,CASC2,COG1,ZNF385A,CS,RGS6,FEZ2,CCDC144A,HDAC9,TOMM20,ZNF804A,KIAA0753,CEP170,SNAP91,DNM1L,PLXNC1,EMX2,GPHN,PIPOX,EYA1,MRVI1,WAC,FCGR1A,CAP2,FLT1,NBEA,CINP,MEGF11,ARPP21,GCNT2,ARFIP1,GLS,SERP2,LINC01551,HNF4G,C9orf129,SMAP1,IDH3B,IGSF1,INPP5B,NAT8L,MYO7A,SFR1,DPY19L2P2,PCDH9,HERC2P3,CAMKV,XRN1,C11orf49,PIGG,OCIAD1,UBR7,ATP8B4,HSD11B1L,CSRNP3,ATXN2,PEAR1,ARX,DHX30,CPEB4,SMARCD3,MBD5,KIF13A,CMTR2,USP33,SOX3,TNIK,UHRF1BP1L,SRPK2,CLASP2,SLC37A2,ROBO3,SYNE1,ARHGEF12,HHIP,DCBLD1,SGK3,UGT8,CCDC14,ZNF711,LYPD6,ZNF213,PRDM2,SENP7" MicroRNA hsa-miR-6893-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.61E-38 4.83E-34 2.34E-37 2.16E-36 126 665 "SDE2,ABCF1,AS3MT,NDRG3,RNF157,ADD2,PNMA8B,SLC24A4,TXNDC16,APAF1,CPNE5,SHROOM2,AQP6,CDC14B,SFMBT2,ASPA,ATM,ZNF583,BTRC,FOXK1,ZNF555,PTBP2,ISPD,SLC16A4,MYOM2,CFL2,NRXN3,LETMD1,MFSD4A,SLC35F1,CS,IPCEF1,UBXN2A,USP6NL,FAM131B,KIAA0513,PHYHIP,TMEM170A,ELMSAN1,SGSM2,SLC29A4,GNE,SYT15,HEYL,EBI3,IRAK4,MRNIP,VPS26C,ZNF585B,PTK2B,FDFT1,VTI1B,ATP13A4,MSANTD4,HHIPL1,TMEM151A,GABRB1,B4GALNT1,SESN1,GLUL,STARD3,ZNF638,FERMT2,GPR26,ZNF496,KIF3A,BVES,IRAK3,AGBL5,ZNF546,C5orf24,KLHL23,SMAD9,MATN3,PPM1L,MXI1,NBL1,CNOT4,SLC11A2,NRGN,NUCB1,TBC1D25,CDK18,PLEC,SMOX,RETREG2,POLR2F,NCR3LG1,MTMR10,TMEM145,ZNF844,QDPR,MSANTD2,GSTCD,SNX22,PTGR2,HSD11B1L,SBF1,ATXN1,IL17RB,SH3BP2,MYO18A,SLC2A5,PEX26,SOX11,IQSEC2,CDK19,LHPP,ZSCAN29,NEK4,FAM168A,ZC3H4,CAMSAP2,FAM208A,USP22,PCDHA6,AHCYL2,ARL10,ERCC6L2,TPM3,TPM4,SSBP2,USP1,ZNF708,SNX27,MPPE1" MicroRNA hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA_TOP PITA 9.08E-38 5.10E-34 2.47E-37 2.28E-36 80 279 "XKR4,PWWP2A,PITPNM2,OGT,ANK3,ATP2B1,N4BP2L1,LDLRAD4,FMNL3,FOXN3,TAOK2,QKI,COL4A5,CPS1,SOCS5,RIMS4,USP6NL,DBT,ELMSAN1,SPOCK3,SRGAP3,G3BP2,SH3GLB1,ELN,ANKRD13B,MEX3B,AGAP3,FOXO3,CAMKK2,GPR37,BACH2,SMAP1,IGF1,ZIC5,MEST,MITF,MYCN,NEXMIF,NFIA,OPCML,CLDN11,ENPP2,PIK3C2A,PIK3R1,PLP1,PURG,PMP22,EPB41L4B,PRKAB2,SNRK,OXR1,REV3L,GTDC1,KIRREL1,KCNIP2,ATXN1,PPM1E,RUFY2,NAPB,TET1,DOP1A,HECW1,PEG10,SPTAN1,CLASP2,STX1A,CAMTA1,CAMSAP2,UNC5D,ARHGEF12,AP4E1,ZFP91,ZNF346,TRPS1,FNDC5,TUBB2A,WIPF1,CSDE1,NAV3,ADAMTS10" MicroRNA hsa-miR-939:mirSVR_highEffct hsa-miR-939:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.48E-38 5.33E-34 2.58E-37 2.38E-36 108 502 "ABCF1,NDRG3,ADCY6,CCDC85A,ADORA3,PTCHD1,ZFAT,PHF12,PKP4,PPFIA3,SEMA4G,TTLL9,ADGRB1,RGS11,BCL2L2,CA4,LURAP1,USP2,CHRM1,PLEKHB1,NDST3,PPT2,MAP4K4,ARMC8,SLC35F1,CSF1,SEC24C,KATNAL2,DCAF8,PLEKHM1,CHRDL1,DYRK1A,FIS1,EDN1,C3orf18,MFSD10,MRVI1,UBE2E3,IP6K2,AGAP3,DCTN2,HVCN1,AK8,USP21,CELF1,FYN,DKK3,JPH4,ARPP21,STARD3,LOXL3,GPD2,FUT10,PLCD4,GRIK5,SERP2,KAT7,PADI2,ATXN2L,ARHGAP36,LRRC25,KCNC2,KIF5A,KLRC2,VWA5A,NCOA7,MAN2A2,DBNL,MTR,NBL1,NTRK3,PIRT,ZNF655,PPP2R2B,MAPK4,PLPPR1,RASGRF2,ZDHHC4,SEC61A2,SETD5,KCNIP2,CLIP1,PRCD,ASIC4,PEAR1,FBXO11,R3HDM2,ST6GAL1,ST3GAL3,CTXN2,PEX26,BTBD7,SMARCD3,UHRF1BP1L,PBLD,NAT16,CYB561A3,THRA,ZFP91,TNNT1,SLC35A4,ZNF70,TMEM198,DNALI1,WNK3,DOCK8,CAMK1G,PIANP" MicroRNA hsa-miR-3139:mirSVR_highEffct hsa-miR-3139:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-37 6.15E-34 2.98E-37 2.74E-36 127 676 "SDE2,ACADM,ACHE,AS3MT,ACTN1,RNF150,SLC44A5,HACE1,BEGAIN,AMPH,ZFAT,OGT,PPFIA1,DDO,SEMA4G,LINC00173,ASPA,CACNA1G,C5,CAMK2D,ZBED1,SRSF11,TJP2,CNTFR,PREPL,GDA,SNCAIP,OSBPL3,SUSD5,NCAN,PDE4DIP,FAM169A,ST18,GAPVD1,TMEM170A,GIT2,MED24,SMG7,SV2B,NTM,DYRK1A,ABCC5,SGK2,EN2,EPHA5,F8,FABP7,FGF1,ZCCHC17,NSG1,DLL3,STAU2,AP4B1,GABRA1,GABRA2,GAD2,ZMYND11,NEU3,GPM6A,GPM6B,GRIA2,PLCD4,ADAMTS13,LINC00839,GSTT2,IGFBP1,KIF5A,MAT2A,MEST,ADAM22,LYRM9,NELL1,SLCO1C1,NFE2L2,DNHD1,BEST3,ZNF655,HMGCLL1,MAPKAP1,GON4L,MDGA2,TMEM260,ZIK1,C1orf109,PEX5,ZNF615,MARCH1,MSANTD2,RDX,PRRT2,NUDT11,RPRD1A,GSTCD,YY1AP1,LRRK2,SCN3A,CASC3,ITSN1,SEC31A,EPN2,PKNOX2,SIRT2,SHANK2,SLC22A4,ZFP1,MAST1,SNAP25,MYO16,CLUAP1,TTBK2,RGL1,ADHFE1,DMXL2,CRB1,TIE1,TMEM9,PLEKHH2,CCDC14,SLC13A3,SF1,DHX33,PRDM2,PCDH15,ST7,KAT6A,JMJD1C,NLRP3" MicroRNA "ATGTTAA,MIR-302C:MSigDB" "ATGTTAA,MIR-302C:MSigDB" MSigDB 1.36E-37 7.62E-34 3.69E-37 3.40E-36 73 232 "ABR,CSMD3,ADD3,SPOP,GPRASP2,LRCH2,NUMB,DDX3Y,NRP2,MAGI1,CREM,CREB5,PHF14,CTNND2,GAPVD1,MATR3,KCTD8,ELMSAN1,SNAP91,DLX1,CPEB2,DNAJB6,EDNRB,PHF20L1,GPHN,FOXG1,ATP2C1,KHDRBS3,ST6GALNAC3,TBR1,GABRA2,GABRB3,GAD1,SALL3,PPARGC1A,LIFR,MBNL1,MEIS2,MYT1,NFIX,PCDH9,PDE4D,POU3F2,PPARA,PPP2R2C,PPP2R5E,PPP5C,PTPRE,KHDRBS2,LRRTM4,BTBD3,USP33,SON,WDTC1,SOX3,ZCCHC24,SOX11,SP4,CDK19,ANKRD12,UNC5D,ADGRL3,TBL1X,SIRT1,ZFPM2,TPD52,USP1,ZIC3,FMN2,PLPPR5,PAK5,FXR1,CBLN2" MicroRNA hsa-miR-216a:PITA hsa-miR-216a:PITA_TOP PITA 1.38E-37 7.73E-34 3.74E-37 3.44E-36 91 363 "ARID1A,TRMT9B,TMEFF1,ZFYVE28,STK33,NCOA1,ATP1B3,JAZF1,CDH2,MAGI1,COL9A1,CTNND2,MATR3,PITPNC1,SPATA2,CNIH3,KLHL3,POM121,DYRK1A,SEMA3D,RBM12,FAM13A,MBNL2,KMT5B,EGR3,COPS4,ELAVL2,TMEM35A,PAN3,EN2,OLIG2,RCAN2,EPHA5,MED12L,AFF2,MEGF11,CPLX2,PCDH17,PPARGC1A,KDM2B,EML4,PTPRT,FAM19A2,ADAMTS6,KLF12,HNF4G,JAK2,KCND2,AFDN,HNRNPM,CNOT4,GPR85,CDK14,ANKRD16,TNPO2,FAT3,TMEM255A,ZYG11B,ATXN1,FNIP1,SMPD3,MAGI3,FAM214B,SLC6A8,CPEB4,RIMS1,KDM4B,SOX5,KIF21B,KDM3A,SP4,ARHGAP26,ELOVL4,ZC3H4,ANKRD28,TAC1,ADGRL3,DMXL2,CUX2,RPGRIP1L,ZFP91,NR2E1,TRPS1,CADM1,TBC1D15,ZIC1,SLC30A4,PMEPA1,NAV3,PDSS2,VANGL2" MicroRNA hsa-miR-654-3p:PITA hsa-miR-654-3p:PITA_TOP PITA 1.45E-37 8.12E-34 3.93E-37 3.62E-36 71 219 "TMEM132B,ZNF608,OSBPL8,TAOK1,BEGAIN,ATP2A2,CADM3,NRP2,SYNJ1,JAZF1,CACNA1I,QKI,RIMS2,ARHGAP24,CTIF,ELMO1,MTX3,SEMA3D,CELSR3,EGR3,FGF14,ANKFY1,AFF2,SORBS1,AHCYL1,CPLX2,PPARGC1A,PCLO,RAPGEF1,PSIP1,KLF12,ZIC5,KCND2,GIT1,NEFM,NPTX1,OPCML,PCDH18,PACSIN1,NXPH1,MED1,QRICH1,ARID4A,RDX,SYNDIG1,HUNK,SCN8A,CPEB3,SLC1A2,SLC6A8,SLC8A2,CPEB4,RCOR3,FAM126B,LRRC4,TBL1X,SATB2,WASHC4,TJP1,HEY2,NR2C2,KCNE5,TUB,SF1,REEP1,CA10,CADM2,SNX27,PDSS2,HNRNPA3,FXR1" MicroRNA hsa-miR-548c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-37 8.53E-34 4.12E-37 3.80E-36 110 522 "SDE2,SPOP,TRMT9B,OGT,PARG,TMEFF1,ZBTB10,EIF4G3,BMPR1B,CACNA1A,CALM1,CANX,CCNT1,CDC27,NDST3,CNN3,HS3ST5,CPS1,CTNND1,USP6NL,HEPH,MYEF2,FBXO25,GUCD1,MTX3,CPEB2,GOLGA7,ELAVL4,DCTN4,EN2,CEP85L,CACNG2,DLC1,FOXO3,NPTN,ST6GALNAC3,MSANTD4,GALC,NCKAP1,FAXC,GPR75,LUZP2,EML4,GRK4,TPPP,ZIC5,ITGAV,METTL21A,KCNB1,KCNN3,LAMP2,PAXBP1,MSANTD3-TMEFF1,MAT2A,MEIS1,MITF,MKLN1,CCDC80,MYBPC1,SLC11A2,NUCB2,SNTG1,OLA1,CCSER2,PSAT1,FAT3,DRAM2,MAPK7,GDPD1,PTCH1,RAB5B,RBBP6,SLC25A36,SETD5,NCBP3,MRAS,TRA2B,SGK1,SH3BP2,CHD9,PEX26,SLC6A8,ATF7IP,IGSF9B,TMCC1,SON,SP4,HECW1,SRPK2,EPB41L3,NXT2,ELOVL4,DIP2A,FAM208A,TJP1,TLL2,TRPS1,ZNF711,ZNF708,ZNF28,LYPD6,DHX33,PRDM2,PRDM10,TRIM16L,NUP214,CERS6,FXR1,GAN,SPATA13" MicroRNA hsa-miR-345:mirSVR_highEffct hsa-miR-345:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.60E-37 8.98E-34 4.34E-37 3.99E-36 112 540 "PLEKHH1,INTS2,ZNF578,PCDH10,PHF12,PPFIA1,UPRT,KSR1,SCAPER,CACNB4,USP6,NUMBL,SRSF11,KMT2C,PPT2,FBXO7,TJP2,NIPBL,TOGARAM2,HS3ST5,CRMP1,MROH8,SEC24C,USP6NL,CYBB,GPRASP1,ZEB2,DDX46,CHRDL1,E2F6,FAM13A,APH1A,KMT5B,ASB3,EPB41L2,EPS8,ADGRV1,SCML2,IP6K2,SORBS1,DLL3,STAU2,GABRA2,GALR1,ATP8A2,ADAM28,GFRA2,RNPS1,ZNF638,LOXL3,FAM19A2,AP4S1,MAEL,HPS5,HMGCL,USP54,IL11RA,OLFM3,KLRC2,NCOA7,PACRG,SMAD1,MDM4,KITLG,MOBP,NFE2L2,NUCB2,OPA1,PDE4B,MAPKAP1,GON4L,GDPD2,STK32A,STRC,FIGN,PBRM1,RAVER2,ELP2,SLC30A10,ASAP3,ST3GAL3,CTXN2,SLC2A5,SLC20A2,MBD5,KDM4C,ATP10B,SSTR2,MLC1,FGD4,ZFR2,NUDT10,SYP,SYT4,ADGRL3,EHBP1,ZEB1,SIK3,TF,HEY2,SSBP2,CADM1,CCDC136,LAT2,ZNF45,MKRN3,PRDM2,PCDH15,C12orf4,RTN4,SMIM8,GAN" MicroRNA hsa-miR-4308:mirSVR_highEffct hsa-miR-4308:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.67E-37 9.40E-34 4.54E-37 4.18E-36 105 479 "ADD3,LRFN2,MTUS1,RTL9,SPOP,OGT,NT5C3B,CAPRIN2,DPY19L3,NRP2,GYG2,CACNB2,KALRN,CLDN10,ZMYM4,LRRFIP1,IGFBP7-AS1,TJP2,NIPBL,ARMC8,SLC4A8,ABI3BP,ACBD5,ANKRD44,CST3,GPRASP1,KIAA0586,DBN1,RHOBTB1,RABGAP1L,DLG2,FAM13A,EGFR,EPB41L2,SRRM1,RCSD1,EXTL2,FAM198B,FGF14,FGFR1,BAIAP2,SPECC1,CELF1,DKK3,TMEM8B,PCDH11X,FERMT2,ATF7,TDRKH,FUT10,RAPGEF4,GRIA4,GRIK3,KAT7,PSIP1,NCKAP1L,SMAP1,SOWAHA,KIF5A,VWA5A,SRSF12,MOBP,NRBP2,SCG3,SLC11A2,NTRK3,PDYN,VPS13C,STRC,RAD51D,ATG16L1,GTDC1,MRPS18A,CARF,PCMTD2,HOGA1,TRA2B,CHD9,SEPHS1,BTBD7,ATF7IP,SOX3,SP4,EMC1,CAND2,NFASC,MPRIP,UNC5D,AGTPBP1,FBXW11,PCDHB3,TK2,RGMB,TRPC1,TSC1,GORASP1,SLC47A2,EMSY,PRDM2,PRDM8,URM1,SLC17A7,PDSS2,MSRB3,SPATA13" MicroRNA hsa-miR-518d-3p:mirSVR_lowEffct hsa-miR-518d-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.92E-37 1.08E-33 5.19E-37 4.78E-36 112 541 "ACTN2,NDRG3,FMNL2,PLEKHG5,PSMG3-AS1,RNF150,OLMALINC,KLHL13,LRRC7,ALAD,CNTNAP1,APP,ARHGAP5,ASGR1,FUBP1,THSD7A,NGB,PRC1,CCPG1,SRSF11,SOCS6,NRXN1,QKI,SULT4A1,MAP4K4,ARHGEF6,SLC25A27,COL9A1,MYRIP,ZNF521,AKAP12,ANKRD44,GDA,CX3CR1,KCTD8,DAPK1,SIRPA,DGCR5,RHOBTB1,SRGAP3,DMPK,SLC29A4,CDON,EDN1,SGK2,SEMA3D,EIF1,EXTL1,IP6K2,FLT1,NELFCD,SDCBP2,NEURL4,TUBA8,GFAP,PCLO,GRIK1,LINC00839,KLF12,AGBL5,HSD17B1,KCNJ11,LMO1,MOBP,MPP2,SCG3,LYRM9,MYO6,RTL5,NME4,NRGN,OPA1,BEST3,PFKFB2,SSH1,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,FIGN,SLC25A36,CCDC25,WLS,FOXRED2,SCN2B,HSPA4L,BCAN,SHANK2,CPEB4,PDZRN3,SON,KDM3A,ADHFE1,AGTPBP1,MGRN1,ZEB1,RIMBP2,C5orf64,TPM3,RGMB,TRIO,TSC1,UCHL1,CELF4,WNK1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-191:mirSVR_highEffct hsa-miR-191:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.01E-37 1.13E-33 5.45E-37 5.02E-36 89 349 "PWWP2A,AP2A2,AP1B1,PITPNM2,ATP2B1,CACNA1B,CACNA1E,LGI1,CCPG1,RAB3C,B4GALT6,JAM2,NCOR1,PHACTR3,LIN54,DAPK1,ZEB2,CNIH3,DPP6,SIDT2,COPS4,DCTN4,EMX2,F5,CEP78,AMOTL2,DACH2,NEURL4,RAPGEF6,GAP43,ATP8A2,PPARGC1A,GPM6B,GRIA4,TJAP1,FGFBP3,MBD1,MDM4,NRCAM,ZNF655,PLCD1,MAGEL2,NXPH1,PPP2R5E,MAPK9,PIGG,PTPRD,RAP1GDS1,RGS3,RGS7,SEC61A2,C12orf49,ROBO1,RPE65,ARMH4,RPS20,SAFB,SATB1,FHOD3,TET1,LIMCH1,RIMS1,CMTR2,NPAS3,ATP10B,MPRIP,ELOVL4,RGL1,NUDT10,COBL,CAMSAP2,TCEA1,SIN3B,SATB2,TCF7L2,ZEB1,PCDHB9,HEY1,TJP1,TPM3,C9orf85,UBE3A,ZNF154,UPF3A,MAP3K12,PARP11,C12orf4,KAT6A,SLC4A10" MicroRNA hsa-miR-501-3p:TargetScan hsa-miR-501-3p TargetScan 2.17E-37 1.22E-33 5.86E-37 5.40E-36 60 153 "CPNE2,ACTN1,NDRG3,ADCY2,OGT,APC,PDE8B,BCL7A,CACNA1E,PTBP2,RUNX1T1,CBFA2T2,DCLK1,DLGAP2,OSBPL3,FAM131B,KIAA0408,KIAA0087,DCC,CPEB2,ABI2,ELAVL2,AHCYL1,ARPP21,PCDH17,RAB30,GRIA1,CIT,PSIP1,KLF12,AGFG1,KCNA1,KCND3,MGAT3,MYCN,OLR1,CLDN11,PDE3B,PPP2R2C,PPP2R5E,RPL15,RIMKLA,AMER2,ATXN1,SCN2A,SCN2B,RPH3A,FAM126B,PDZD2,PEG10,ATP11A,PSD3,ITGB3BP,DOK6,CADM1,EML6,CSDE1,EVI5,FXR1,GAN" MicroRNA hsa-miR-502-3p:TargetScan hsa-miR-502-3p TargetScan 2.17E-37 1.22E-33 5.86E-37 5.40E-36 60 153 "CPNE2,ACTN1,NDRG3,ADCY2,OGT,APC,PDE8B,BCL7A,CACNA1E,PTBP2,RUNX1T1,CBFA2T2,DCLK1,DLGAP2,OSBPL3,FAM131B,KIAA0408,KIAA0087,DCC,CPEB2,ABI2,ELAVL2,AHCYL1,ARPP21,PCDH17,RAB30,GRIA1,CIT,PSIP1,KLF12,AGFG1,KCNA1,KCND3,MGAT3,MYCN,OLR1,CLDN11,PDE3B,PPP2R2C,PPP2R5E,RPL15,RIMKLA,AMER2,ATXN1,SCN2A,SCN2B,RPH3A,FAM126B,PDZD2,PEG10,ATP11A,PSD3,ITGB3BP,DOK6,CADM1,EML6,CSDE1,EVI5,FXR1,GAN" MicroRNA hsa-miR-142-3p:Functional MTI Functional MTI miRTarbase 2.29E-37 1.28E-33 6.18E-37 5.69E-36 94 389 "ZNF608,MTUS1,TAOK1,ALAD,PHF12,PPFIA1,APC,USP37,LGR5,CDC14B,ARNTL,ATP2A2,ATP2B1,MTMR9,BACH1,PROM1,CALM1,SOCS6,CLTA,ABCG2,HECTD1,CNN3,ACBD5,CPS1,CLOCK,CSNK1G3,SOCS5,PUM1,USP6NL,IP6K1,PITPNC1,CPEB2,DNAJB6,ABCC9,GOLT1B,EIF5,DCTN4,STX2,ACSL4,SUCO,SLC37A3,MSANTD4,NCKAP1,FREM1,MALT1,RAB30,GNAS,EML4,KAT7,FICD,HMGB1,C5orf24,IL6ST,ZNF678,ITGAV,KCND3,KIF5A,ARHGAP12,MKLN1,AFF1,NAP1L2,NEFH,STRN3,PPP2R2C,RAB39A,RIPOR1,ATG16L1,PCMTD2,RPE,DOCK10,FNDC3A,PEX26,BTBD7,CLUAP1,TAB2,TROVE2,SS18,DIP2A,NSFL1C,SYPL1,SYT4,TMEM136,PCDHGA10,PCDHGA2,THBS4,ARL10,ZMYND8,MTCH1,NSD2,RICTOR,ZNF24,SIGLEC10,PDSS2,RNF170" MicroRNA hsa-miR-4321:mirSVR_lowEffct hsa-miR-4321:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-37 1.31E-33 6.30E-37 5.80E-36 72 227 "FMNL2,ZFAT,PPFIA1,APBB2,PCDHGB4,ATP2A2,ADGRB3,RGS9,KSR1,CACNA1E,RUNX1T1,ARHGEF10,HDAC9,DAPK1,PITPNC1,POM121,SPOCK3,HS3ST4,EIF1,SYNCRIP,EFCAB2,GABRA2,GABRG2,RAB30,LRRC75A,SCIN,SCRT2,ITGAM,KCNQ3,KLC1,PAXBP1,MAN2A2,SRSF12,NOVA1,DNHD1,PCDHGC3,PRKACB,FAM120C,SLC25A48,SH3TC2,RFX4,KCTD17,ATXN2,ASRGL1,SHMT2,BCAN,CLSTN1,IFT122,USP33,UNC5B,TSPYL2,MAPK8IP3,KAZN,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,KAT6B,TRIO,UBE2H,XRCC4,EML6,NLRP3" MicroRNA hsa-miR-518b:mirSVR_lowEffct hsa-miR-518b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.33E-37 1.31E-33 6.30E-37 5.81E-36 107 498 "ACTN2,NDRG3,PLEKHG5,PSMG3-AS1,RNF150,OLMALINC,KLHL13,LRRC7,CNTNAP1,AMER3,APP,ASGR1,FUBP1,THSD7A,NGB,PRC1,CCPG1,SRSF11,SOCS6,NRXN1,QKI,SULT4A1,MAP4K4,ARHGEF6,SLC4A7,MYRIP,ZNF521,ANKRD44,CX3CR1,DAPK1,SIRPA,DGCR5,RHOBTB1,SRGAP3,ZNF582-AS1,DMPK,SLC29A4,CDON,EDN1,SGK2,SEMA3D,EIF1,EXTL1,IP6K2,NELFCD,SDCBP2,NKX6-2,TUBA8,GFAP,PCLO,GRIA1,GRIK1,LINC00839,AGBL5,HSD17B1,SYTL4,MOBP,SCG3,LYRM9,MYO6,RTL5,NME4,NRGN,OPA1,BEST3,PFKFB2,SSH1,PIK3CD,GRAMD1C,ELOVL2,PTN,SH3TC2,FAT4,OXR1,RADX,SLC25A36,CCDC25,FBXW7,WLS,FOXRED2,MIR124-2HG,SCN2B,BCAN,SHANK2,CPEB4,MAPKBP1,PDZRN3,SON,KDM3A,ADHFE1,AGTPBP1,MGRN1,ZEB1,ZMAT3,RIMBP2,C5orf64,TPM3,TRIO,TSC1,UCHL1,CELF4,WNK1,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-4258:mirSVR_lowEffct hsa-miR-4258:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.40E-37 1.35E-33 6.48E-37 5.97E-36 88 342 "SYS1,ADD2,GOLGA7B,FAM135A,PCDHGB4,EIF4G3,BCL7A,FGF17,ZNF599,NUMBL,PPT2,SLC4A8,MICAL2,CSNK1E,PDE4DIP,GREB1,RUBCN,KATNAL2,SCRN1,DUSP9,DNAJB6,EFNB3,TNK2,ELN,OLIG2,ECSIT,TMEM132C,APOPT1,ARFGAP2,CGREF1,TMEM151A,GABRB1,SIGLEC8,GFER,TNRC6A,ZNF638,HMGCL,ZNF678,INSM1,KCNQ2,LOC100128239,MAT2A,MRPL42,MX1,PABPC1L2A,RCOR2,NNAT,PCDHGC3,NOMO2,PLCL1,BCAS3,SIDT1,GON4L,ACSS3,PRRT2,CARF,SLC6A8,ARFGAP1,ANKRD36,FNBP1,ZSWIM8,KIF1B,ACSBG1,EHBP1,TPCN2,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,SIK3,TPD52L2,VIPR2,NDRG4,CRB2,PCBP4,PARP11,DOCK8,TMEM63C,FRMD6" MicroRNA hsa-miR-6778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-37 1.35E-33 6.48E-37 5.97E-36 127 681 "AS3MT,XKR4,RNF157,ESYT2,MTA3,AK2,ZNF578,TAOK1,CDC14B,SLC7A14,SLC4A4,ATP1B3,ALDH7A1,LDHD,GYG2,CACNA1A,ZBED1,GPR37L1,RAB3C,PLAA,STOML1,IGLON5,COL9A2,RTTN,ENTPD4,HINFP,CSNK1E,SOCS5,KIAA0408,RIPOR2,TMEM170A,RABGAP1L,KRBA2,CNNM1,IRAK4,RGS17,TUBD1,PLEKHO1,EPB41L1,MTSS1L,SLC43A2,MRPL37,TLR7,FDFT1,TESK2,FGFR1,PCYOX1,APOPT1,PDLIM5,CELF1,MSANTD4,KIAA1841,SRCAP,RAB40B,GRK4,KIF3A,RNF165,MFSD2A,HAS2,DDX19B,HMGB1,ATCAY,EID2B,SHISAL1,NKD1,KCNK3,LIMS1,NCOA7,GPR155,MBD1,MOG,P2RX7,PIK3C2A,ZNF655,FAM216A,ZNF426,STRN3,FITM2,GDPD1,PIGG,PTAFR,OCIAD1,ZSCAN2,ZNF844,NWD1,GTDC1,DCUN1D2,C12orf49,PGBD4,PTGR2,FOXRED2,DRAXIN,SCN2B,GALNT10,HSPA4L,ZFP30,PEX26,FAIM2,FAM126B,SP2,CLUAP1,SSTR2,INKA2,MAPK8IP3,DIP2A,STAC2,AJAP1,ZC3H4,WWC1,AGTPBP1,ACSL6,KIAA0930,TMEM151B,GPRIN3,PCDHA6,ZMAT3,ARL10,CBX5,ERCC6L2,PARD3,CFAP298,AGMO,ZNF70,ZBTB16,ZNF225,WIPF2,MPPE1" MicroRNA hsa-miR-513c:PITA hsa-miR-513c:PITA_TOP PITA 2.60E-37 1.46E-33 7.01E-37 6.46E-36 73 234 "SNX30,HECW2,ALCAM,OGT,PPP4R4,CALM1,TRIM41,FOXN3,QKI,MAP4K4,PREPL,RBM39,CSNK1G3,CNTNAP2,SPOCK2,GIT2,HP1BP3,DYNC1I1,SLC12A6,RBM12,ELAVL3,PAN3,EXTL2,CLVS1,HPCAL4,FOXG1,SYNCRIP,NBEA,STAG2,MEGF11,GABRB3,CAB39,CPLX2,PCDH17,TMEM121B,CIT,SYNPO,IDH3A,DOCK7,MBNL1,NEXMIF,NEFM,NEFH,NOVA1,NALCN,XRN1,MINDY2,PPP2R5C,PTPRD,FAM120C,PTX3,ZYG11B,RIT2,SLITRK3,PPP4R3A,SLC6A8,SOX1,KDM4C,ARHGAP26,VAMP1,SYN1,SYPL1,FBXW11,TIAM1,TRPS1,UBE3A,FLRT2,ZIC3,ZNF711,SLC30A4,PHTF2,FXR1,SOCS4" MicroRNA hsa-miR-122*:mirSVR_lowEffct hsa-miR-122*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.63E-37 1.48E-33 7.09E-37 6.53E-36 97 414 "XKR4,ADARB2,SLITRK1,UNC5A,ZNF687,MYH7B,BCAS1,AQP4,ARNTL,ADAM23,ADGRB3,SYNJ2,MMD2,PTBP2,DCLK1,QKI,COX4I1,AHCTF1,FAM131B,YTHDC1,ZNF804A,KIAA0319,DDX46,DTNA,KLHL5,ETV1,ZNF461,GTF2IRD2,WDR83,JKAMP,SMC2,APOPT1,CELF1,GABRB1,GABRG1,FAM184B,TNRC6A,SERP2,HMGCL,HSF2,IFI16,C5orf24,PLD5,ITGAM,KCNA4,KCNA6,KCNJ3,SYTL4,MEF2C,SESN3,MYO9A,DNHD1,OXTR,FXYD1,PDZRN4,STRN3,LRRC49,UHRF1BP1,ARHGEF10L,SLC25A36,PBRM1,TMEM100,EPHA10,ARMH4,NCBP3,FOXRED1,FHOD3,PAAF1,FAM81A,PKNOX2,SLC6A8,SLC14A1,ATF7IP,SMARCA4,MAST1,MBD5,KDM4C,CDK19,VWA3A,ZNF106,TIAM1,ERCC6L2,DAAM2,CSMD1,RUNDC3B,OSBP2,ZNF709,CFAP298,ZBTB16,CADM2,PRTFDC1,DNALI1,PDSS2,FBXO36,ACTR3B,RNF170,LAS1L" MicroRNA hsa-miR-6499-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-37 1.71E-33 8.19E-37 7.55E-36 147 881 "ABCF1,CLK4,XKR4,NDRG3,PLEKHG5,ELFN2,ADCY2,ESYT2,SLC24A4,HECW2,HACE1,TXNDC16,ZNF578,AMER3,AQP6,SFMBT2,ASPA,STX16,DOCK11,ST3GAL5,FOXK1,PTBP2,CBS,CBFA2T2,MYOM2,EVI5L,CDR1,CCPG1,JAM2,NRXN3,PLAA,TPP1,ACBD5,OSBPL3,MYADM,GAPVD1,KIAA0513,TMEM170A,IP6K1,DNAL1,DBT,YTHDC1,HP1BP3,GUCD1,MTX3,DMD,DNAH9,KRBA2,FEM1B,SYT15,HEYL,OPTN,MRO,ABI2,RASA4,MRNIP,TUBD1,COQ7,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,SEC23B,SPECC1,KBTBD12,MSANTD4,TRAF3IP2,DISC1,CRCP,GNG4,CNDP1,LILRA2,GRK4,KIF3A,KAT7,SCRG1,IGF1,DOCK7,IBA57,LIMS1,GPR155,MAT2A,MKLN1,CCDC80,MXI1,OPRL1,OLA1,ZNF655,CCSER2,GPSM2,PLCD1,FAT3,TATDN3,FITM2,MTMR10,PEX2,CEP97,PLEKHB2,RBBP8,ZYG11B,TRIM68,ALG9,PGBD4,SNX22,UEVLD,PTGR2,NCBP3,FNIP1,SLC30A10,HSPA4L,SHC4,MAGI3,BTBD3,ATF7IP,ANKRD36,SCN3B,FNBP1,ERC1,LHPP,ZNF621,MAPK8IP3,ZSCAN29,KLHL7,ALG1,WWC1,VWC2,SATB2,USP22,ZNF106,THRA,BHLHB9,TPM3,PPIL6,SSBP2,USP1,MEAF6,LAT2,AGMO,ZNF74,ZNF154,EVI5,WIPF2,TIGD6,RNF170" MicroRNA hsa-miR-24-1*:mirSVR_highEffct hsa-miR-24-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-37 1.97E-33 9.47E-37 8.72E-36 95 399 "NCKAP5,KLHL32,CDC7,CC2D2A,SMIM17,ARHGAP20,CCDC146,LGR5,ASPH,ZSCAN18,BTK,CALB1,CALM1,ZMYM4,SRSF11,CLCN4,ARMC8,ARHGEF10,NRSN1,CYBB,DOCK4,GAPVD1,TOMM20,G3BP2,RAB39B,DTNB,EMX2,ABCA8,MEX3B,SGIP1,ARPP21,TUBGCP4,TUBA8,GLS,KDM2B,CECR2,GRIA4,PLCD4,ADAMTS6,GUCY1B1,HAS2,IGF1,IGSF1,KCNK2,KIF5C,SYT9,MOBP,MYO9A,NCAM2,VWA2,CHAMP1,OLR1,PCDH9,NXPH1,PPP2R5C,TMEM260,ENOX1,OXR1,SLC6A15,LGR4,DRAXIN,HOGA1,TNFRSF19,SCAF8,FERMT1,SLC1A3,TET1,CPEB4,CDK5RAP2,MYH15,LIMCH1,SNRPN,PDZD2,BDP1,SRPK2,ATP10B,SSTR1,ERBIN,ANKRD28,TCF7L2,TCF12,DOCK9,NSD1,GZF1,BHLHB9,CADM1,WIPF1,NSD2,PORCN,ZNF711,LYPD6,HNRNPA3,PHTF2,RNF170,RNF146" MicroRNA hsa-miR-564:mirSVR_lowEffct hsa-miR-564:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.59E-37 2.01E-33 9.65E-37 8.89E-36 108 509 "SYN3,XKR4,SLC12A5,MTA3,AP2A2,ZNF578,LRFN1,PPFIA2,CNTNAP1,PHYHD1,ARHGDIA,TMEM108,ATP1B3,RGS9,SYNJ2,BAIAP3,TRIM41,DCLK1,DLGAP1,LHX2,NRXN3,CLTA,MAP4K4,NIPBL,CABP1,SMARCAL1,CREB5,GREB1,BRINP1,DBI,ZEB2,HP1BP3,COPS7A,SMG7,TMCC2,HS3ST2,CDON,SRPK3,ANKRD13B,RABEPK,SLC43A2,EYA1,ZIC4,FLT1,FLYWCH1,FAM49B,BRSK1,PRUNE2,STON1,RAPGEF4,GRM2,BTN2A1,HSD17B1,IL11RA,KCNJ11,KCNK1,KLC1,SYT9,MOBP,BLOC1S2,BCO1,N6AMT1,PCDH8,PCDH9,FAM216A,SMOX,C11orf49,MAPKAP1,SDK2,SPATA6,MASP1,PTCH1,TUG1,SLC25A48,RASGRF2,KLHL11,ZFHX4,EXD2,SNX22,EPHA10,SYNDIG1,SOX8,MAPK12,LINC00461,TRIM46,HSPA4L,DZIP1,SLC8A3,EFHD1,LIMCH1,SP2,SSPO,MAPK8IP3,KANK1,TCF7L2,PCDHB6,AHCYL2,NR2E1,WBP2,PRMT8,NUTM2A,RPRM,PLEKHH2,CLIP2,SLC26A10,MEIS3,NUP214,LAS1L" MicroRNA hsa-miR-1225-5p:mirSVR_highEffct hsa-miR-1225-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.59E-37 2.01E-33 9.65E-37 8.89E-36 94 391 "CSMD3,SLITRK1,ADD2,PWWP2A,KIAA1324,FGD2,CCDC146,PKP4,APP,CDC14B,ATP2A2,ATP2B1,MTMR2,NIPA1,IL33,MMD2,CLDN10,ZFP28,DZIP3,TMEM170A,ZBTB24,KLHL3,DDX46,EXOG,DTNB,ABI2,CALCRL,MRPL10,ETV1,FGF11,SEMA4D,UFM1,FAM49B,ERGIC3,STAU2,MSANTD4,MEGF10,SALL3,IQGAP2,C15orf41,GFAP,GLS,PCDH11X,GRIA4,KIF3A,LINC01102,DIPK1A,METTL21A,KCNK1,KCNMA1,INSYN2,MOBP,MRPL42,MYO9A,NFE2L2,NTRK2,OPHN1,GPR137C,PLTP,RC3H2,HYDIN,SAMD9,PTCH1,PTHLH,ELOVL2,PTPRD,FAT4,RAP1GAP,GTDC1,RGR,PBRM1,RNASEL,FAM192A,RMI1,SEMA6D,IL17RB,SUPT20H,ZFP30,BCAN,NLGN1,ABLIM3,UNC80,KDM3A,SPART,STAU1,ADAMTS17,TAL1,DICER1-AS1,UBE2H,BEST1,REEP1,ZNF189,CA10,SMIM8" MicroRNA hsa-miR-196b-5p:TargetScan hsa-miR-196b-5p TargetScan 3.95E-37 2.22E-33 1.06E-36 9.78E-36 79 277 "BRAP,PCDH19,ARHGAP20,LCORL,MAP4K3,GAS7,AQP4,IGDCC4,CASK,CHRD,BACH1,MTMR3,GYG2,CALM1,NRXN1,FAM19A5,PCYT1B,LETMD1,ENTPD4,PPP1R16B,PPP6R2,HDAC9,HP1BP3,BLOC1S6,EBF1,RASGRP1,MBNL2,ABI2,ELAVL4,RGS17,LRRC17,FGF14,GALC,SALL3,C15orf41,FAXC,PRUNE2,PRDM5,FRMD5,DDX19B,HLF,IGF1,RBPJ,SCRT2,LRRTM3,KCNC2,KLHL23,LRRC4B,LRP1B,RSPO2,NAP1L1,NME4,OPCML,PBX1,PDGFRA,PFKFB3,SCHIP1,MAPK8,PTPRG,RDX,ERI2,GTDC1,RAVER2,ATP8B4,FNIP1,CPEB3,PEG10,RAP1GAP2,LARP4,DIP2A,AJAP1,ACSL6,RPGRIP1L,DOK6,NR2C2,FRRS1L,FLRT1,RICTOR,GAN" MicroRNA hsa-miR-196a-5p:TargetScan hsa-miR-196a-5p TargetScan 3.95E-37 2.22E-33 1.06E-36 9.78E-36 79 277 "BRAP,PCDH19,ARHGAP20,LCORL,MAP4K3,GAS7,AQP4,IGDCC4,CASK,CHRD,BACH1,MTMR3,GYG2,CALM1,NRXN1,FAM19A5,PCYT1B,LETMD1,ENTPD4,PPP1R16B,PPP6R2,HDAC9,HP1BP3,BLOC1S6,EBF1,RASGRP1,MBNL2,ABI2,ELAVL4,RGS17,LRRC17,FGF14,GALC,SALL3,C15orf41,FAXC,PRUNE2,PRDM5,FRMD5,DDX19B,HLF,IGF1,RBPJ,SCRT2,LRRTM3,KCNC2,KLHL23,LRRC4B,LRP1B,RSPO2,NAP1L1,NME4,OPCML,PBX1,PDGFRA,PFKFB3,SCHIP1,MAPK8,PTPRG,RDX,ERI2,GTDC1,RAVER2,ATP8B4,FNIP1,CPEB3,PEG10,RAP1GAP2,LARP4,DIP2A,AJAP1,ACSL6,RPGRIP1L,DOK6,NR2C2,FRRS1L,FLRT1,RICTOR,GAN" MicroRNA hsa-miR-498:PITA hsa-miR-498:PITA_TOP PITA 4.15E-37 2.33E-33 1.12E-36 1.03E-35 76 256 "ADAR,MARCH4,NCOA1,ATP2B1,C5,WASF1,CACNA1A,CAMK2G,TMEM257,LETMD1,ZEB2,DLG2,DLG3,CPEB2,DYRK1A,ATL1,PAN3,ERBB4,EYA1,ZIC4,FGF1,PRKAG2,CELF1,GABRB3,GATM,TCERG1,SPIN1,FERMT2,EML4,GRIA2,WIF1,KLF12,BACH2,MIER3,GABARAPL2,DHX35,KCND2,STXBP5,MATN3,LRP1B,MEIS1,KITLG,HCN1,KCNK10,PDE4B,PIK3R1,CCSER2,PURG,PRRX1,PPP2R5C,PPP3CA,SNRK,PTCH1,PBRM1,ITSN1,NLGN1,BTBD3,WDR47,FAM214B,PKNOX2,ABTB1,TMCC1,SOX11,ITPRID2,LARP4,NCDN,ANKRD28,DICER1,RIMBP2,TP53BP2,TSC1,RPRM,FLRT2,CADM2,EVI5,HNRNPA3" MicroRNA hsa-miR-596:mirSVR_highEffct hsa-miR-596:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-37 2.46E-33 1.18E-36 1.08E-35 84 314 "ACADM,PPFIA1,APBA2,SHTN1,ZFYVE28,DDX3Y,SNAI3-AS1,CACNB2,ACBD5,CNRIP1,CREM,GDA,PDE4DIP,ERC2,CYBB,FBXL5,SGSM2,FAM107B,CHRDL1,DNM2,DPYSL2,DTNB,EDN1,ATL1,C3orf18,GMPR2,PCYOX1,ATP13A4,FLT1,C15orf41,GRIA2,PLCD4,ADAMTS13,ADAMTS8,LINC01551,ELOVL5,HMGCR,MSL1,DISP2,LMO2,HECTD2,COL28A1,JAKMIP3,NRBP2,MT3,CTNNA3,NEK1,NTRK2,P2RY1,CNTN3,PDGFRA,PLIN1,SMIM7,HMGCLL1,ING3,PPP3CB,GRAMD1C,CNTLN,PTPRG,RAB3IL1,CARF,ATAT1,SUPT20H,NTNG1,MAGI3,ATF7IP,ANKRD36,SNRPN,SP4,TTBK2,NSFL1C,FAM168A,VPS13A,FRYL,ARL10,BHLHB9,ELP5,WIPF1,ZSCAN26,XKR7,MRPL47,KLHDC1,AP3B2,ST8SIA2" MicroRNA hsa-miR-621:mirSVR_highEffct hsa-miR-621:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-37 2.46E-33 1.18E-36 1.08E-35 95 400 "CLK4,ACTN1,KDM5D,CCDC85A,SEMA6A,ALCAM,ANK2,ANK3,MIER1,CAPRIN2,NUMB,ARHGEF7,CFL2,IGFBP7-AS1,AKAP7,SLC25A27,CP,PREPL,HAPLN1,ANKRD44,CS,DZIP3,GREB1,CCDC144A,MYEF2,HP1BP3,CASP8AP2,SEMA3D,FAM13A,EPHA5,EPHB1,FOXF2,IP6K2,SYNCRIP,AKAP3,PHYHIPL,CAB39,ZMYND11,DNER,GLS,GPD2,SLC2A6,ZHX1,MIER3,HTR2A,RBPJ,JAK2,KCNH2,VWA5A,MRPL42,PABPC1L2A,NF1,PDE4D,GPR85,PFKFB2,PFKFB3,CAMKV,EPB41L4B,VPS13C,ZFHX4,MEG3,RTKN,ZNF568,AP1AR,ATXN7,ELMOD1,TRIM46,SELL,ASRGL1,KIF16B,PAAF1,WDR37,SMARCE1,SNCA,HECW1,VPS13A,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CDH22,TMPO,FAM124A,TP53BP2,TRIO,FNDC5,CLHC1,VSNL1,DOCK8,PAK5,RNF170,SNX14" MicroRNA hsa-miR-149-5p:TargetScan hsa-miR-149-5p TargetScan 5.50E-37 3.09E-33 1.48E-36 1.36E-35 90 361 "ADCYAP1R1,ADD1,AP1B1,PCDH19,LTBP4,CACHD1,KIAA1614,ATP2A2,BCL2L2,NRP2,BID,FUBP1,CACNA1I,CABP7,CCNT1,REPS2,IGFN1,CHRM1,NCOR1,RIMS4,CNTNAP2,FRMPD4,KIAA0087,JAKMIP2,KLHL3,DLG4,RPS6KL1,FARSB,EDNRA,CNNM1,HEYL,EIF5,RGS17,PLEKHO1,EPB41L1,FGF11,AMOTL2,DCTN2,GPR153,B3GAT1,BRPF3,RNPS1,GPT2,KAT7,GUCY1A2,NXPH3,ARHGAP19,NCKAP1L,HMGCR,C2orf72,KCNB1,KCNJ10,KCNN3,KIF2A,KIF5A,GIT1,MSI1,NFIX,NNAT,NOVA2,GPR88,PAK3,PDE1B,PDGFRA,BCAS3,PXK,RAB3IL1,RAD51D,GTDC1,PRIMA1,RNF220,ACER3,MYO18A,ATF7IP,FAM126B,IQSEC2,NCDN,PHLDB1,ARC,C12orf76,HHIP,FBXL16,CBX5,RASD2,ELP5,PLEKHH2,BCL2L13,POLR3H,INTS3,MSRB3" MicroRNA hsa-miR-1202:mirSVR_highEffct hsa-miR-1202:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.61E-37 3.15E-33 1.51E-36 1.39E-35 111 538 "ACADM,SLITRK1,PTCHD1,MAP4K3,GPAM,TMEM263,CAPRIN2,TTLL9,GYG2,CLDN10,LARGE1,NUMBL,NRXN3,SULT4A1,BTF3L4,CREM,PPP6R2,BOC,TOX,DAPK1,SIRPA,ARMCX4,FBXL5,KIAA0753,KIAA0319,ZC3H11A,DDX46,SV2B,RABGAP1L,DMTF1,ECM2,DNAJB6,AASDH,EPB41L2,ADGRV1,TAOK3,SEC24B,FLT1,ATP2C1,SARAF,ZNF234,ERAP1,SULT1C4,SESN1,PCDH17,RND1,COPS8,ZNF638,WDFY3-AS2,FUT10,EML4,RAPGEF4,CLASRP,HTR2A,MSL1,IL6ST,LRRTM3,JAK1,JAK2,KCNK2,KLRC2,PAXBP1,TM6SF1,LYRM9,CDK14,RETREG1,PPP3CA,PRKAB2,PRKCB,MDGA2,PXK,FAT4,RBBP6,ARHGEF10L,ZFHX4,SPIN3,ZC3H14,MCMBP,ABCA11P,RTKN,NTNG1,SYBU,PAAF1,ZNF365,ARHGEF40,ZFP1,SMARCA4,IFT122,DOK5,KIF1B,SSPO,ADHFE1,STXBP1,SYNE2,TMEM150C,PUM2,PCDHA5,HIF3A,LEFTY2,FBXL16,MTMR14,TPM1,SYNPO2,NTSR2,CLHC1,ZNF610,WRN,KCNT2,FTSJ1,LAMP5,FAM219B" MicroRNA hsa-miR-517a:mirSVR_lowEffct hsa-miR-517a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.72E-37 3.78E-33 1.80E-36 1.66E-35 89 354 "ADGRF5,OGT,CCDC146,PKP4,KCNAB2,APBB2,TNRC6C,PPFIA3,LGR5,EIF4G3,BSN,CACNA1D,BRSK2,USP6,CDK11B,ARHGEF2,DGCR9,FAM189A2,GALNT9,DOCK4,MATR3,KCTD8,DAPK1,DNAJC6,JAKMIP2,LYPD1,SV2B,DTNA,RASGRP1,EPHA5,ENPP6,CDHR1,RTN3,PTK2B,FLT1,DACH2,GALNT15,DISC1,FERMT2,GPR19,LINC00839,RNF165,GPR45,NKD1,KIF5C,A1BG-AS1,MOBP,P2RY13,NEUROD1,OXTR,PDE4D,PFKFB4,PFKP,CDK14,SEMA5B,SLC36A4,PPP2R2C,PRKCZ,EPDR1,MAPK9,PTPRH,PEX5,RASGRF2,ZYG11B,UBR7,RGS12,LGI2,C12orf49,TRIM46,SHC4,DHX30,SLC12A2,RCOR3,WDTC1,STAU1,STXBP1,FGD4,WDR7,UGT8,TBC1D15,SLC47A2,CELF4,STOX2,PRDM8,RNF103,MPPE1,WNK2,EPM2A,ACTR3B" MicroRNA hsa-miR-499-5p:PITA hsa-miR-499-5p:PITA_TOP PITA 7.73E-37 4.34E-33 2.07E-36 1.91E-35 71 224 "SDE2,ABAT,OSBPL1A,LRCH2,ZBTB10,CACNB2,PTBP2,CDO1,CFL2,MS4A7,NRXN3,QKI,HECTD1,ACBD5,SLC35F1,RNF14,FAM131B,DCC,ZEB2,MYEF2,USP3,DPP6,RBM12,EPB41L2,SRRM1,TESK2,CHL1,AHCYL1,EML4,MAP4K5,C5orf24,RBPJ,ARHGAP12,MAP2,MEIS1,ZC3H12B,NOVA1,OMG,XRN1,MINDY2,PPP3CA,PTCH1,RET,RNF220,PBRM1,FBXW7,NCBP3,SCN3A,FAM19A1,SOX6,CHD9,TRIM67,SLC12A2,SOX5,SOX11,CDK19,FAM168A,SYT1,EHBP1,AZIN2,RALYL,FLRT2,ZIC3,ZNF711,REEP1,MEIS3,SLC30A4,EVI5,WNK3,RNF146,SLC4A10" MicroRNA hsa-miR-129-3p:PITA hsa-miR-129-3p:PITA_TOP PITA 9.30E-37 5.23E-33 2.49E-36 2.30E-35 73 238 "XKR4,ADD2,KLHL13,AQP4,CACNA1E,USP6,DGKI,DLGAP2,NUMBL,RCBTB2,HECTD1,RCHY1,CREB5,SEC24C,PLCXD3,RIMS3,TOMM20,SPATA2,MYEF2,POM121,RHOBTB1,SACS,DLG2,CALN1,FAM135B,ELAVL3,RCAN2,FGF13,NPTN,AHCYL1,JPH4,GRIN2D,PTPRT,FRMD3,KLF12,NEK1,GPR137C,SEMA5B,PIK3R1,POLG,MED1,PKIA,MAPK3,ELOVL2,RIPOR1,RAB5B,GTDC1,UBR7,ZNF532,ROBO1,TMEM100,SNX22,BAALC,ABLIM3,RIMS1,SCN3B,NMNAT2,ERBIN,SYT4,CAMSAP2,CLASP1,FRYL,TIAM1,HEY1,FNDC5,CADM1,FAM155A,FLRT2,ZBTB38,REEP1,NAV3,PHTF2,VANGL2" MicroRNA "AACTGGA,MIR-145:MSigDB" "AACTGGA,MIR-145:MSigDB" MSigDB 1.07E-36 6.03E-33 2.87E-36 2.65E-35 71 225 "ABR,SLC25A25,CSMD3,ADD3,SEMA6A,SPOP,FAM135A,EPB41L5,CACHD1,ZBTB10,SLC4A4,BSN,MYRF,CFL2,ZFYVE9,QKI,MAP4K4,CABP1,TBPL1,AKAP12,CTNND1,ARHGAP24,TM9SF4,ELMO1,ZC3H11A,SRGAP3,MTX3,DPYSL2,DYRK1A,EFNA3,VPS13B,GPHN,ACSL4,SPSB4,AMOTL2,AFF2,ABLIM2,FAXC,GGT7,KDM2B,C1QL4,BACH2,GABARAPL2,BLOC1S2,MYO5A,NAP1L1,XRN1,PPP3CA,SLC6A15,REV3L,RGS3,RGS7,CCDC25,RTKN,ATXN2,SCN3A,ZFP2,KIF21A,FNDC3A,SLC1A2,CPEB4,SOX11,ZNF423,ARHGAP26,KIF1B,PRRC2C,ANKRD28,TRIM2,PSD3,SNX27,PAK5" MicroRNA hsa-miR-665:TargetScan hsa-miR-665 TargetScan 1.08E-36 6.08E-33 2.90E-36 2.67E-35 89 356 "RNF157,ADCYAP1R1,KIF6,OGT,CNTNAP1,KIAA1614,CCDC74A,CCAR2,CABP7,HAP1,CBFA2T2,CDR1,IGFN1,DLGAP3,NIPBL,RAB26,PCYT1B,COL9A2,GDA,RIMS4,ECE2,DGKG,PLEKHM1,PHC2,CNNM1,HEYL,BSCL2,ELN,ENO2,MTSS1L,ENPP6,CORO2B,FCGRT,FGFR1,AGAP2,NSG2,B4GALNT1,JPH4,ATP8A2,GRIK3,BTN2A1,IL1RAPL1,FICD,FRMD3,HMGB1,KCNB1,KCNN3,ADAM11,DBNL,FXYD7,NNAT,NODAL,NRGN,OPCML,PALM,PDPK1,GNG2,GDAP1L1,RASGEF1B,MAPK4,PTPRB,DPF2,ALG9,DRAXIN,FAM19A1,FAM102A,PPP1R9A,MYO18A,CCDC92,PKNOX2,RADIL,KIF21B,MAPK8IP3,AJAP1,C3orf70,SEMA4A,NSD1,ARHGAP9,CRTC1,CBX5,DDHD1,DOK6,FNDC5,AMOT,LGI4,POLR3H,GDPD5,KAT6A,GAN" MicroRNA hsa-miR-665:mirSVR_highEffct hsa-miR-665:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.15E-36 6.48E-33 3.09E-36 2.84E-35 121 634 "KCNH8,SYS1,KDM5D,NDRG2,SLC12A5,AP2A2,ADGRF5,AMPH,OGT,FGD2,UPRT,ALS2,PPFIA3,CCAR2,CHID1,TTLL9,NRP2,CFLAR,RAB29,CAST,CCK,CDH18,MAGI1,ADGRG1,RCBTB2,NDST3,ABCG2,NIPBL,FAM149A,SLC4A8,TOGARAM2,MYRIP,CHD1L,OSBPL3,PDE4DIP,NRSN1,TM9SF4,HP1BP3,DDX46,SGSM2,EXOG,DYNC1I1,DPH1,DPP6,PDCD6IP,ELN,DUSP27,EXTL2,FCGRT,GORAB,OLFM1,EVL,SEMA4D,SLC37A3,NOP56,WDR83,ZCCHC17,JPH4,GFRA2,GNAO1,GRIA4,PLCD4,SERP2,GRM8,MFSD2A,VSIG4,KCNN2,KCNN3,MDM4,MEIS1,SAMD5,PABPC1L2A,NNAT,NODAL,CNOT4,DNHD1,NUCB2,OXTR,TREM2,PC,PFKFB2,CDK14,GDAP1L1,PLCB2,ING3,RASGEF1B,MAPK9,GDPD2,SPDL1,USP47,RASGRF2,RFX2,RPRD1A,EXD2,MEG3,ZNF331,FAM19A1,CASC3,NTNG1,KANSL3,PKNOX2,IFT122,UNC80,ERC1,CEP68,SULF2,ASTN2,SEMA4A,PJA1,SYNE1,RNF216P1,VWCE,ERCC6L2,SMUG1,DCBLD1,TSC1,DNALI1,TRIM16L,PDSS2,TRAM2-AS1,SLC4A10" MicroRNA hsa-miR-365*:mirSVR_highEffct hsa-miR-365*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-36 7.13E-33 3.39E-36 3.13E-35 101 455 "UNC79,GPAM,ALS2,VAT1L,ARHGAP5,ARNTL,PDE8B,CDK5R1,SYNJ1,CACNA1B,THSD7A,INA,CDO1,PLEKHB1,EPS15L1,PPT2,IQCK,ACBD5,PLCH2,SOCS5,RIMS2,HDAC9,DCAF8,ZFYVE16,PLPPR4,DLG2,ECM2,GOLT1B,EBF1,PHC2,EIF1,CEP85L,ABCA8,FAM198B,TAOK3,C1orf61,CAP2,IP6K2,ANKFY1,CAMKK2,ATP2C1,AHCYL1,GAP43,ZNF559,RND1,PCLO,GRID1,RNF165,MYLK2,KCNJ3,LAMP2,LIMS1,MBNL1,LDLRAD3,BLOC1S2,RTL5,ODF2,OPA1,CNTN3,PDGFRA,TMIE,FTO,C11orf49,PPP2R5E,PRKCZ,HYDIN,SIDT1,ANKHD1,PXK,PTPRE,RET,UBR7,RGS3,EXD2,HSD11B1L,RYR3,R3HDM2,DHX30,SEPHS1,SLCO1A2,RCOR3,SNRPN,IZUMO4,SPART,ATP10B,CLSTN2,POGZ,SLC37A2,DNMBP,ZFP90,ZFP91,WIPF1,P2RY12,ZNF24,ZNF142,MAP3K12,PRTFDC1,STOX2,PHTF2,SLC4A10,FAM198A" MicroRNA hsa-miR-7110-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-36 7.40E-33 3.52E-36 3.24E-35 88 349 "ACTN2,GRAMD1B,NLGN4X,MTA3,SORCS2,SPOP,ARHGDIA,ASCL1,ATP1A3,ATP2B1,PROM1,LDLRAD4,CABP7,CD86,CDH8,GPR37L1,CLU,RIMS4,CST3,PLXNA4,PITPNM3,GAPVD1,LONRF1,SMG7,TMCC2,RCAN1,CELSR3,ELAVL3,EMX2,SLC43A2,NRN1,GABRA1,GABRG2,GALR1,PCDH17,GJB1,GPT2,PARD3B,GRID1,PTGDR2,FRMD3,SHISA6,LSAMP,CD200,DDR2,ZDHHC22,PALM,PDE3A,GDAP1L1,PLCL1,KANSL1,SNRK,PTPRN2,SH3TC2,RDX,ZYG11B,SCN2B,GALNT10,ZFP30,CPEB3,ZFP1,SMARCE1,IGSF9B,LIMCH1,CLUAP1,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,IQCE,TMEM151B,TGFBR3,HHIP,FBXL16,BHLHB9,TNS1,SMUG1,TMPRSS5,TSC1,UBE2H,DPYSL5,CADM2,PRDM10,NAV2,MPPE1,DPF3" MicroRNA hsa-miR-1825:mirSVR_highEffct hsa-miR-1825:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.33E-36 7.47E-33 3.55E-36 3.27E-35 104 481 "ACHE,CLK4,SLC12A5,BEND6,GPR158,ABCD2,PCDH10,MRTFA,UPRT,ARRB1,ASPH,ATP1A2,SEC11C,CACNB2,CDH2,CFL2,CNOT8,CLCN3,ARMC8,BTF3L4,SLC35F1,CTH,GIT2,ARMCX4,ZNF804A,DLG2,DTNA,PHC2,KLHL5,GPR61,PHF20L1,RTN3,EXTL2,FER,CELF1,GALC,KIAA1841,TUBGCP4,WASHC2A,PCDH17,SPIN1,ZNF782,CECR2,PCLO,GRIA4,GRIN2C,HAS2,SCIN,JAK1,KCNJ3,KIT,KLC1,AQP11,POC1B,MITF,CD200,LYRM9,NBL1,NCAM1,NPTX2,NTRK2,GPR88,SNTG1,PDE1C,GPR85,CDK14,NLGN3,PKN2,MAPK10,HYDIN,APTX,MDGA2,EML5,FAM184A,PRRT2,FIGN,RFX3,CARF,ROBO2,ATP8B4,LRRTM4,NTNG1,FNDC3A,SORCS3,SP2,ENKUR,ITPRID2,SS18,ERBIN,KLHL7,VPS13A,FBXW11,TMEM136,SMG6,SZT2,HHIP,TIAM1,UGT8,ZNF17,TMEM237,PLPPR5,KCNAB1,RTN4,JPH3" MicroRNA hsa-miR-502-3p:PITA hsa-miR-502-3p:PITA_TOP PITA 1.41E-36 7.93E-33 3.77E-36 3.47E-35 62 169 "ACTN1,ADCY2,NLGN4X,KLHL13,OGT,CDC14B,BCL7A,JAZF1,PTBP2,DCLK1,ZMYM4,DLGAP2,CHD5,CTNND1,FAM131B,KIAA0408,DGKB,NR1D2,CPEB2,DRD1,DNAJB6,ATL1,ELAVL2,ZIC4,GRIA2,CIT,KLF12,KCNA1,MGAT3,MYCN,NEFM,CLDN11,PCDH9,PDE3B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,FAM120C,ZFHX4,ATXN1,SCN2A,SCN2B,SCN3A,NTNG1,SLC8A2,RIMS1,PDZD2,PEG10,PRRC2C,ATP11A,PSD3,ITGB3BP,TJP1,DOK6,CADM1,UBE2H,TMEM198,CSDE1,ADAMTS9,ST8SIA2,GAN" MicroRNA hsa-miR-558:PITA hsa-miR-558:PITA_TOP PITA 1.45E-36 8.15E-33 3.87E-36 3.57E-35 58 146 "ELFN2,PCDH19,TBC1D14,PDZD4,ANK1,MTMR3,BSN,CABP7,KALRN,FMNL3,KMT2C,HECTD1,DBN1,C2CD2L,ALKBH8,SNAP91,SV2A,G3BP2,DPYSL2,ABCC5,AGAP2,FLNC,SESN1,RAPGEF1,GRIN2D,GRM3,KAT7,ATXN2L,SYNPO,NEGR1,KCNA1,NAT8L,MEIS1,MXI1,MYT1,NRGN,OPHN1,PDE4B,USP47,DPF2,KIF21A,SLC1A3,SEPHS1,SLC8A1,NKAIN2,ANKRD28,SATB2,RPGRIP1L,ZFPM2,ZNF106,HEY2,RIMBP2,RBFOX2,CADM1,ZFAND5,SNX27,KAT6A,SENP7" MicroRNA hsa-miR-590-5p:PITA hsa-miR-590-5p:PITA_TOP PITA 1.83E-36 1.03E-32 4.89E-36 4.50E-35 76 261 "RALGAPA1,PTCHD1,CASKIN1,BCL7A,FUBP1,KRIT1,CFL2,SOCS6,CNOT8,CNTFR,TENM4,ARHGAP24,DLG2,SLC12A6,SNX29,RASGRP1,PLEKHA1,PAN3,KCNMB2,SCML2,ST3GAL6,ANKFY1,NPTN,STAG2,CHL1,GABRG2,MSTN,GRM1,FRMD3,HNRNPK,RBPJ,IL12A,KCNA1,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MYO6,NELL2,PIK3R1,PLP1,PPP3CA,MAPK10,TMEM260,ARID4A,RDX,PBRM1,AP1AR,SATB1,SLC30A10,SOX6,CPEB3,FBXO11,BTBD3,SLC8A3,TET1,PDZD2,SOX2,SOX5,ITPRID2,MPRIP,PHLDB1,PLCB1,CAMTA1,ARHGEF12,TIAM1,SGK3,CADM1,VSNL1,TRIM9,TMEM237,RNF103,WNK3,NETO2" MicroRNA hsa-miR-605:PITA hsa-miR-605:PITA_TOP PITA 1.96E-36 1.10E-32 5.23E-36 4.81E-35 80 290 "ADD3,ADRB2,NLGN4X,TAOK1,FAM135A,OGT,LRCH2,CHRD,BSN,CACNA1A,TRIM41,RUNX1T1,LRBA,CDC42,CDH2,MAGI1,CFL2,B4GALT6,CLOCK,SH2B1,LRIG1,CSNK1G3,SLITRK5,TCAF1,DGKG,ZEB2,SRGAP3,MTX3,NR1D2,MBNL2,EGR3,TMEM132E,PAN3,EPB41L1,F3,MSTN,PCDH17,PCDH11X,LPAR4,ADAMTS6,HNRNPK,NKD1,NEXMIF,MYT1,ZC3H12B,NEUROD1,NFIA,NUMA1,PDE3B,OLA1,LRP12,MED1,PTCH1,PTX3,SH3TC2,ST6GALNAC6,NCBP3,CSRNP3,ATXN1,NLGN4Y,TRIM67,FAM126B,MYT1L,POGZ,ZC4H2,LRRC4,GSE1,ANKRD12,ADGRL3,TCF4,CUX2,SLC44A1,KAT6B,TRPC1,CADM1,EIF4ENIF1,UBE3A,FLRT2,NSD2,RNF146" MicroRNA hsa-miR-501-3p:PITA hsa-miR-501-3p:PITA_TOP PITA 2.11E-36 1.19E-32 5.63E-36 5.18E-35 62 170 "ACTN1,ADCY2,NLGN4X,KLHL13,OGT,CDC14B,BCL7A,JAZF1,PTBP2,DCLK1,ZMYM4,DLGAP2,CHD5,CTNND1,FAM131B,KIAA0408,DGKB,NR1D2,CPEB2,DRD1,DNAJB6,ATL1,ELAVL2,ZIC4,GRIA2,CIT,KLF12,KCNA1,MGAT3,MYCN,NEFM,CLDN11,PCDH9,PDE3B,PPP2R2C,PPP2R5E,PPP3CA,PPP3CC,FAM120C,ZFHX4,ATXN1,SCN2A,SCN2B,SCN3A,NTNG1,SLC8A2,RIMS1,PDZD2,PEG10,PRRC2C,ATP11A,PSD3,ITGB3BP,TJP1,DOK6,CADM1,UBE2H,TMEM198,CSDE1,ADAMTS9,ST8SIA2,GAN" MicroRNA hsa-miR-377*:mirSVR_highEffct hsa-miR-377*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.24E-36 1.26E-32 5.96E-36 5.49E-35 114 573 "SERPINA3,ASIC1,DPY19L2P4,PITPNM2,ANK1,FGD2,GPAM,PHYHD1,MIER1,ARRB2,CAPRIN2,NCOA1,N4BP2L1,TRIM41,VXN,CLDN10,ARHGEF2,CDC42,CDH10,CDH18,SYNPR,RAB33A,ABCG2,FHL5,IQCK,ARMC8,MYRIP,UBXN2A,CYBB,HEPH,MYEF2,RHOBTB1,DNM1,DMTF1,TOM1,DYRK1A,FAM135B,EDNRB,C8orf37,VPS13B,ERBB2,EFS,CDHR1,FAM198B,GORAB,FGF11,SLC37A3,FYN,ZNF234,GHR,ZNF276,CCDC184,RNFT2,ADAMTS6,MSL1,MYLK2,CREG2,CLEC18A,MSR1,CTNNA3,RTL5,NAP1L1,NFE2L2,PBX1,PDE2A,SIDT1,PIGG,CNTLN,PTHLH,ZSCAN32,ZDHHC14,RNASE1,TMLHE,ROBO1,ATP8B4,GLDN,ACER3,TCP11L1,SCN7A,MYO18A,DOCK10,CNKSR2,SEC31A,FAM214B,PKNOX2,ZNF334,TET1,MBD5,MYT1L,NFASC,TAB2,SYN1,SYT1,SLC37A2,SYT4,POPDC3,VWA3A,DOCK9,HIF3A,TIAM1,ERCC6L2,SEZ6L,TRIO,STXBP4,RUSC1,RFTN2,FAM181B,DPYSL5,LAMP5,CA10,TMEM178A,CASC15,TRAM2-AS1,NETO1" MicroRNA hsa-miR-34a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-36 1.35E-32 6.37E-36 5.87E-35 131 735 "AXIN2,ESYT2,AP2A1,AP2A2,ANK3,APAF1,DGKZ,ALS2,PDXK,NCOA1,NUMB,MTMR9,CFLAR,BMP7,MTMR2,AIFM1,SEPT7,ZMYM4,LRRFIP1,EVI5L,MAGI1,FOXN3,CLTB,TJP2,BTF3L4,SLC4A7,CLOCK,CSF1R,CYBB,GAPVD1,PHF19,DAPK1,CTIF,ZEB2,CEP170,G3BP2,CDON,RCAN1,TOM1,DNAJB6,E2F5,RBM12,EIF4G1,MRNIP,EPB41L2,EPHA5,ERBB2,ACSL4,NELFCD,APOPT1,STAG2,ACSS1,POLL,PRRC2B,FUT10,TPPP,GRM7,FICD,GYG1,ATG4C,DDX19B,ATXN2L,KLF12,HMGB1,HNF4G,IL6R,KCNH1,KCNH2,KIF2A,KIT,KLC1,KTN1,L1CAM,STMN1,MAP4,MDM4,MKLN1,MOV10,MYCN,NASP,NEUROD2,CNOT4,OPA1,TREM2,PDGFRA,TMOD2,XRN1,PPARA,MAPK3,UHRF1BP1,QDPR,USP47,FIGN,CARF,MCMBP,COPZ1,CPEB3,SMARCA4,SMARCC2,SON,SOX2,PEG10,SPTAN1,RBM26,POGZ,STX1A,GANAB,ZC3H4,SUPT5H,SYNE2,SYT1,MMS19,CAMTA1,FAM208A,ACSL6,SATB2,TCF7,TPCN2,PUM2,SLC35G2,SIRT1,TP53BP2,TPD52,TPM1,TSN,SSBP2,BCL2L13,RICTOR,RTN4,FXR1,SOCS4" MicroRNA hsa-miR-4266:mirSVR_highEffct hsa-miR-4266:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.69E-36 1.51E-32 7.15E-36 6.59E-35 107 511 "ARID1A,SLC44A5,KCTD16,OSBPL1A,OGT,PHF12,PARG,ADGRB2,KSR1,LURAP1,CANX,RUNX1T1,ZMYM4,CHN2,RAB28,CLTC,COL11A2,ANKRD44,ZSCAN23,CYBB,KATNAL2,TCAF1,ZEB2,FBXL5,CEP170,AK5,GOLT1B,EDNRA,EIF4G2,DNAJC27,MRVI1,NRN1,EFEMP1,FCGRT,ZCCHC17,PDLIM5,DACH2,TBR1,PHYHIPL,GABRB3,GAD1,DISC1,GK,GLS,GLUL,GPM6B,GRIA2,DIDO1,ZNF546,ZIC5,IL11RA,ZNF678,INPP5B,KCNN2,PIK3AP1,MBP,MDM4,XRRA1,ERICH3,COL28A1,MYBPC1,MYO7A,SFR1,GNG2,ZNF655,RETREG1,C11orf49,PPP2R5C,RASGEF1B,PRKACB,PSMA6,MDGA2,TMEM255A,FAT4,LGR4,ABCA11P,SCN2B,LRRTM4,ITSN1,CHD9,R3HDM2,ZNF365,FAM214B,SLC12A2,SLCO1A2,SMARCA4,CLUAP1,KDM4C,CLSTN2,NXT2,TTBK2,C12orf76,TACR1,TBCEL,FBXW11,WDR7,ARHGAP9,TF,HEY1,R3HDM1,RUSC1,TTTY15,FSTL5,ZNF225,RNF103,ST7,ZNF30" MicroRNA hsa-miR-324-5p:mirSVR_highEffct hsa-miR-324-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.69E-36 1.51E-32 7.17E-36 6.60E-35 88 352 "ACADM,SYS1,ADD2,PCDH19,CDC42BPA,MAP4K3,SUGT1P4-STRA6LP-CCDC180,PKP4,API5,APP,MIER1,ATM,FUBP1,CCKBR,TMEM257,DGKI,LGI1,FAM189A2,NIPBL,FHL5,CNTN1,PCYT1B,RTTN,TOGARAM2,CNRIP1,HINFP,SIPA1L1,USP6NL,DOCK4,DBI,RABGAP1L,DMD,DNAH9,PDCD6IP,RCAN1,OPTN,TMEM35A,CEP78,FGF11,DISC1,GRIA2,FAM19A2,ARHGAP36,IDH3A,ZIC5,KCND2,KIF5C,MAT2A,SYT9,MGAT3,MT3,MYO7A,NELL1,CAMKV,CCSER2,PLP1,PPP2R5E,PRKCG,APTX,CNTLN,PTPRD,PTPRE,RAD52,RNASEL,ZNF532,SETD5,EXD2,SATB1,ITSN1,FBXO11,NAPB,RCOR3,RIMS1,TMCC1,SEPT8,SULF2,SEPT3,SLC19A3,CRB1,ARL10,R3HDM1,TMEFF2,GUSBP1,ZNF189,HPS4,RNF170,CBLN2,GAN" MicroRNA hsa-miR-1227:mirSVR_highEffct hsa-miR-1227:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.92E-36 1.64E-32 7.75E-36 7.14E-35 96 417 "TTYH1,NCKAP5,CDC7,KLHL13,ANXA7,CNTNAP1,ALS2,CACHD1,SHTN1,ADAM23,ADAM15,BMPR1B,C5,PTBP2,CLDN10,CDH18,CLGN,QKI,LETMD1,ZNF521,PNKD,SEC31B,RGS6,ERC2,CX3CR1,CYBB,HDAC9,ARHGAP32,ZFYVE16,HEPH,HP1BP3,SNAP91,PHC2,FRY,GOLGA7,EPHA5,EPHB1,GTF2IRD2,PSD2,BRSK1,NEURL4,DKK3,HBS1L,ZMYND11,WASF3,GLRB,DCLK2,GPD2,STMN2,GRIA2,GRM8,KIF3A,CLASRP,NEGR1,HTR2A,NKD1,KCNJ16,ZFYVE27,MBNL1,SRSF12,NF1,NUCB2,P2RX7,PBX1,PCSK1,PDGFRA,POU3F2,PPP2R5C,PPP2R5E,WBP1L,FAM120C,DPF2,RNASEL,CCDC82,GSTCD,KIRREL1,NCBP3,SLC1A3,SEPHS1,RAB3GAP1,SLC15A2,NSFL1C,KLHL7,SYNE2,DOCK9,TEX15,DDHD1,SEZ6L,CHST5,UBE3A,FAM47E,PDSS2,DOCK8,ST7,JMJD1C,TRAM2-AS1" MicroRNA hsa-miR-765:PITA hsa-miR-765:PITA_TOP PITA 2.96E-36 1.66E-32 7.87E-36 7.25E-35 64 183 "ASIC1,ARID1A,UNC5A,SEMA6A,SYNJ1,CACNA1G,BTRC,CAMK2D,CAMK2G,RUNX1T1,FMNL3,DCLK1,FOXN3,CNTFR,AKAP5,ZNF385A,PNKD,CTNND1,GAPVD1,IST1,G3BP2,CHRDL1,DLG3,EFNA3,NRN1,TAOK3,AFF2,TMEM107,C15orf41,CPLX1,AHDC1,GFRA2,GUCY1A2,CELF3,BACH2,KCNA1,KCNJ11,MAT2A,MEIS2,NFIX,NTRK3,OMG,KCTD15,PRRX1,LRRN3,MAPK10,CYB561D1,ATXN2,FAM102A,SLC11A1,SMARCA4,SOX11,SP2,SEPT3,NSFL1C,SYT11,VAMP1,SYN1,TCF4,THRA,LRRC8A,TPM3,CADM1,ZIC2" MicroRNA "CTATGCA,MIR-153:MSigDB" "CTATGCA,MIR-153:MSigDB" MSigDB 3.11E-36 1.75E-32 8.26E-36 7.61E-35 67 202 "XKR4,OSBPL6,ANK1,USP28,APC,APP,SEMA4G,ARHGAP5,CDK13,SLC4A4,BSN,CAMK2G,CANX,MAGI1,DLGAP2,ZFYVE9,CLTC,QKI,CNN3,AKAP6,CREM,MFAP3L,KLHL3,DLX1,DMD,EFNA3,SCML2,TESK2,CAMKK2,DOT1L,PPARGC1A,RNF165,SCRT2,KCNA6,KCND1,MAT2A,KCTD6,TAGLN3,NEUROD1,NFE2L2,PIK3R1,CCSER2,LRP12,PPP3CA,KANSL1,MAPK4,ROBO2,RYR3,SFPQ,SLC1A2,BTBD7,EPC1,SNAP25,SNCA,SOX11,PLCB1,SYT1,CUX2,ZFPM2,HEY2,SGK3,FLRT2,SPHK2,DPYSL5,SLC30A3,PRDM2,NAV2" MicroRNA hsa-miR-378b:mirSVR_highEffct hsa-miR-378b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.23E-36 1.81E-32 8.57E-36 7.89E-35 124 669 "SORCS1,SLC44A5,ARHGAP20,FAM135A,FGD2,DDO,TNRC6C,PLA2G4C,EIF4G3,NOL4,BCL2L2,NRP2,ZNF599,CFLAR,ARHGEF7,IL33,CA4,CALB2,SLC25A14,CDC27,LGI1,TIGD7,KIAA1549L,DNAJB5,C4orf33,AHCTF1,ZFP28,CREM,ARHGEF10,USP6NL,FRMPD4,DCC,GRIN3A,DSCAM,DYRK1A,GOLT1B,HIPK3,RBM12,SH3GLB1,CELSR3,KMT5B,SPEG,FABP7,FCGR1A,FCGR3A,FGF12,ATP5PD,FOXG1,FLT1,C2orf88,CAMKK2,ATP2C1,NSG2,ST6GALNAC3,MPP6,GABRB1,GABRG2,ERAP1,GLS,GNAS,GPT2,TDRKH,GRIA4,GRIN2C,ZNF496,GSTM5,SLC2A6,ZHX1,HMGB1,SMAP1,MYLK2,IL6ST,IL11RA,KIF2A,KIF5C,MAP6,MARK1,CD200,LYRM9,NAP1L3,NCAM1,NDP,NEK1,NEUROD1,NF1,NFE2L2,CHAMP1,LOC100128398,PAK3,CAMKV,C11orf49,TRHDE,PRPSAP2,SIDT1,PTPRD,USP47,BAALC,KCNIP2,KCNIP1,SORCS3,MBD5,IQSEC2,EPB41L3,NEK4,SEPT8,PLCB1,CAMTA1,AGTPBP1,VWA3A,DMXL2,FRYL,TF,ZFPM2,AP4E1,GZF1,PPIL6,GUSBP1,PLPP4,SLC26A10,EML6,ZNF189,EPM2A,CAMK1G,ZNF248" MicroRNA hsa-miR-21:PITA hsa-miR-21:PITA_TOP PITA 3.29E-36 1.85E-32 8.72E-36 8.03E-35 76 263 "PTCHD1,CASKIN1,BCL7A,FUBP1,KRIT1,CFL2,SOCS6,CNOT8,CNTFR,TENM4,ARHGAP24,DLG2,SLC12A6,SNX29,RASGRP1,PLEKHA1,PAN3,KCNMB2,SCML2,ST3GAL6,ANKFY1,NPTN,STAG2,CHL1,GABRG2,MSTN,GRM1,FRMD3,HNRNPK,RBPJ,IL12A,KCNA1,LIFR,MATN2,MBNL1,CHIC1,MEF2C,MEIS1,MYO6,NELL2,PIK3R1,PLP1,PPP3CA,MAPK10,TMEM260,ARID4A,RDX,PBRM1,AP1AR,SATB1,SLC30A10,SOX6,CPEB3,FBXO11,BTBD3,SLC8A3,TET1,PDZD2,SOX2,SOX5,ITPRID2,MPRIP,PHLDB1,PLCB1,CAMTA1,ARHGEF12,ZFPM2,TIAM1,SGK3,CADM1,VSNL1,TRIM9,TMEM237,RNF103,WNK3,NETO2" MicroRNA hsa-miR-659:PITA hsa-miR-659:PITA_TOP PITA 3.32E-36 1.87E-32 8.81E-36 8.12E-35 74 249 "SDE2,SLC12A5,USP31,ANK1,ARHGAP5,NCOA1,ATP2B1,CACNB4,KALRN,CBFA2T2,ARHGEF2,SEPT7,CDC42,CDH8,LGI1,CNN3,CABP1,SLC35F1,NCOR2,RGS6,ARHGEF10,SLITRK5,CTNND1,FRMPD4,DNAJC6,JAKMIP2,MFAP3L,MAGI2,FAM107B,ABI1,CLVS1,SCML2,CEP78,FGF12,HPCAL4,BRPF3,PPARGC1A,LYVE1,PCDH11X,RNF165,NEGR1,MAP2,NFIX,GPR88,PCSK1,PRTG,PIK3C2A,PIK3R1,MINDY2,MAPK9,RELN,SNRK,HUNK,RTKN,SEMA6D,SCN2A,FNIP1,NLGN1,SLC12A2,PALLD,TMCC1,CDK19,SRPK2,FAM208A,UNC5D,TCF4,TCF12,DOCK9,ARHGEF12,SLC30A4,ITM2C,PAK5,FRMD6,DPF3" MicroRNA hsa-miR-592:PITA hsa-miR-592:PITA_TOP PITA 3.56E-36 2.00E-32 9.42E-36 8.68E-35 66 196 "ASIC2,GPR158,ANK3,LRRC4C,ZFYVE28,STX16,ATP2B1,CACNB2,THSD7A,SPAG9,NRXN3,QKI,AKAP6,PLCXD3,LONRF1,MAGI2,G3BP2,DYRK1A,FOXO3,CPLX2,PCDH17,HLF,NEGR1,TCEAL6,C5orf24,KCND2,LRP1B,MOV10,MYCN,NCAM1,NFIA,NOVA1,NPTX1,PCDH9,PDE4D,OLA1,CDK14,PTPRD,FAM120C,SUSD4,GTDC1,WLS,SH3GL3,PPP4R3A,SLC8A1,RCOR3,SNAP25,FAM126B,ZCCHC24,SP2,LMO3,LRRC4,KANK1,PRRC2C,ARHGEF9,ANKRD28,UNC5D,ADGRL3,ACSL6,TIAM1,MTMR14,TJP1,KCNT2,WNK3,HNRNPA3,CERS6" MicroRNA hsa-miR-3147:mirSVR_highEffct hsa-miR-3147:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.64E-36 2.04E-32 9.64E-36 8.88E-35 105 495 "KLHL32,ADORA3,KIDINS220,SLC24A4,RTL9,ZNF687,AMT,PHF12,CNIH2,PKP4,PHYHD1,PPFIA3,BRINP2,MMD2,CACNA1B,CACNA1D,USP2,INA,CLCN3,CRYBB1,CSF1R,CSF2RA,ERC2,KATNAL2,HP1BP3,SV2B,ABI1,KMT5B,VPS13B,EPHB1,RCSD1,FABP7,TBC1D16,PPP1R1B,SLC9B2,CAP2,AKAP3,GABRA1,ERAP1,TMEM8B,LRRC37A6P,GCK,TUBA8,PCDH17,BRD8,TNRC6A,MSL3,CCDC184,GRIK2,GRM7,LINC00839,SLC2A6,MAEL,KCND1,KIF5C,STMN1,MYO7A,MYO9A,P2RY13,IDNK,NF1,NUCB2,P2RX7,PDYN,BEST3,PACSIN1,RAB39A,MASP1,PTK2,PTPRE,SEC61A2,NUDT11,CARF,SNX22,NEK11,EPHA10,FBXW7,ZNF671,PRR5L,ATAT1,SARS,ARX,FAM214B,ELMO2,SPART,ATP10B,ZC4H2,SEPT8,ADHFE1,MTCL1,ZFP90,SIK3,ITGB3BP,LEFTY2,AP4E1,TIAM1,CSMD1,NPL,FLRT2,BCL2L13,MDH1B,PDSS2,UBE3B,FXR1,GAN" MicroRNA hsa-miR-556-3p:PITA hsa-miR-556-3p:PITA_TOP PITA 3.97E-36 2.23E-32 1.05E-35 9.68E-35 65 190 "GPRIN1,FMNL2,CCDC85A,ADRB2,PCDH19,KCTD16,OGT,LRCH2,SLC4A4,STX16,MTMR9,TMEM257,RCBTB2,PLCXD3,CTNND1,HDAC4,ZFYVE16,MATR3,SIRPA,G3BP2,DNAJB6,MBNL2,ERBB4,ACSL4,VTI1B,NPTN,BRPF3,PPARGC1A,EML4,FAM19A2,HLF,HNF4G,AGFG1,IGF1,MEF2C,MEIS2,NFYA,PDGFRA,FAT3,MED1,PPP2R5C,PKIA,PID1,ZFHX4,SEMA6D,SCN2A,SEC14L1,SCAF8,PPP1R9A,CPEB3,SLC12A2,HECW1,STAU1,SEPT8,ADGRL3,FBXW11,EHBP1,TRIM2,AP4E1,NR2C2,TRPS1,KCNE5,CLDND1,ZFAND5,RGS7BP" MicroRNA hsa-miR-328:mirSVR_highEffct hsa-miR-328:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.01E-36 2.81E-32 1.33E-35 1.22E-34 94 403 "NDRG3,PTCHD1,CC2D2A,ZNF578,ADGRF5,OGT,APOC2,PLA2G4C,CHRD,TTLL9,RUNX1T1,INA,RAB28,NRXN3,SLC4A8,CHD1L,HAPLN1,TIAM2,DYNC1I1,FAM78B,FRY,PHF20L1,PLEKHA1,EN2,MRPL10,TESK2,PRKAG2,WDR83,LRRC37A6P,ADAM28,LYVE1,FERMT2,GPM6A,ATOH8,PADI2,VSIG4,AGBL5,IL6ST,KCNH2,KIF2A,LMO2,VWA5A,CLEC18A,LDLRAD3,ERICH3,MTR,FXYD6,NDUFA5,NELL1,NEUROD1,NEUROD2,DNHD1,NUCB2,P2RX7,PCSK5,PDGFRA,DUSP26,PMP2,MED1,PRPSAP2,SNRK,PTHLH,RALGDS,RBBP6,ERI2,MORC4,RGS4,LRRK2,LGR4,LRRTM4,ITSN1,SLITRK3,CTXN2,PAAF1,SLIT1,SOX11,ZNF423,NECAB1,PLCB1,SYT1,COBL,MTCL1,TCF7L2,SYNE1,KAT6B,TNR,SMUG1,HEPACAM,FRRS1L,PLPPR2,ATP6V0E2,PLPPR5,PCDH15,FRMD6" MicroRNA hsa-miR-516a-5p:mirSVR_lowEffct hsa-miR-516a-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.47E-36 3.07E-32 1.45E-35 1.33E-34 106 506 "ASIC1,SYS1,CSMD2,ELFN2,KIAA1211,OLMALINC,INTS2,CC2D2A,ALCAM,AMPD2,PPFIA2,EPB41L5,PPP4R4,MARCH3,PTBP2,CAMK2G,MTMR7,ASIC3,FAM19A5,CNR1,AKAP7,LETMD1,ZFP28,RBM39,OSBPL3,RASGEF1C,CYBB,ZEB2,CNIH3,LYPD1,SV2B,SRGAP3,DNM1,CD99L2,DPH1,CNNM1,FSD1L,KMT5B,SORBS3,IP6K2,NELFCD,UFM1,NRG3,JPH4,C15orf41,ZNF276,GLS,GPD1,TMEM121B,PLCD4,AP4S1,AGFG1,HSF2,CELF5,SCRT2,ZNF678,ITGAM,KTN1,INSYN2,LIMS1,PIK3AP1,MTTP,MYO9A,NF1,OPHN1,CDK18,PDGFRA,DUSP26,TMIE,ZNF655,PKD1,ANKRD16,SH3KBP1,PRKAB2,SIDT1,CNTLN,RAB5B,RGS4,DCUN1D2,TMLHE,RPS6KA2,SCP2,PAAF1,SLC14A1,ELMO2,OGDHL,ANKRD36,INAVA,CMTR2,DOP1A,SOX2,TSNAXIP1,CLUAP1,NPAS3,PLCB1,CRB1,ITGB3BP,LEFTY2,AKTIP,ANO5,RPL7L1,GPR158-AS1,SPIRE1,CIAPIN1,ZNF248,FXR1" MicroRNA hsa-miR-183:PITA hsa-miR-183:PITA_TOP PITA 5.85E-36 3.29E-32 1.55E-35 1.43E-34 76 265 "SLITRK1,OSBPL8,ANK1,PKP4,GPAM,CDK5R1,REPS2,SRSF11,SOCS6,CLCN3,AKAP12,CSNK1G3,SIRPA,ZEB2,KLHL3,RHOBTB1,SACS,YAF2,ABI2,GOLGA7,MRVI1,CLVS1,SUCO,ARFGAP2,SESN1,GLDC,KDM2B,GNG4,EML4,GRIK2,GRM1,MAP4K5,BACH2,HLF,ICA1,SOWAHA,C5orf24,KCND2,KCNK2,KIF2A,MBNL1,MEF2C,PABPC1L2A,NCAM1,KCNK10,PDE4D,MED1,PPP2R5C,MAPK4,SLC25A36,CYB561D1,ROBO2,CLIP1,SMPD3,SOX6,PPM1E,SLITRK3,TET1,LMO3,ERBIN,NCDN,GSE1,TCF4,CUX2,TCF7L2,TCF12,FRYL,ZFPM2,SLC44A1,TIAM1,RIMBP2,CSMD1,TPM1,TPM3,SLAIN1,FRMD6" MicroRNA hsa-miR-135a*:mirSVR_highEffct hsa-miR-135a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.98E-36 3.36E-32 1.58E-35 1.46E-34 124 673 "CC2D2A,ALCAM,LRFN1,ALS2,ARHGAP5,ASCL1,SLC4A4,RNF182,SYNJ2,SGCE,CAMK2G,ARHGEF25,KRIT1,LRRFIP1,MAGI1,PPT2,CLCN3,NIPBL,ARMC8,SLC4A8,ACBD5,MFSD4A,CTH,DOCK4,MYADM,ARHGAP24,KIAA0513,TMEM170A,KIAA0319,CPEB2,EDIL3,TMTC1,PHF20L1,EN2,ECSIT,FOXO3,PDLIM5,TPK1,OGA,GAB1,GABRA1,GABRG2,PPARGC1A,RUNDC3A,GLUL,GNAL,ZNF782,GUCY1A2,PADI2,NXPH2,TCEAL6,MSL1,USP54,IGSF1,IL6R,IL11RA,ZNF678,LRRTM3,KLRC3,LYPLAL1,SYT9,MOBP,NELL2,NEUROD1,DNHD1,DPY19L2P2,GNG2,GDAP1L1,NOMO2,PURG,PMP2,POU3F2,PPP2R2B,CRLS1,KANSL1,HYDIN,PTPRG,RAD51D,RAP1GDS1,RADX,RGS4,RIC8B,RNASEL,ZFHX4,C12orf49,ZNF568,CCDC112,ATXN7,SCN3A,SHC4,CTXN2,ZNF365,WDR47,SLC8A3,ZFP1,SPART,CLSTN2,ITPRID2,ZNF302,PHLDB1,SYT4,C12orf76,AGTPBP1,WDR7,SYNE1,PCDHB9,PCDHB4,MTMR14,TMPO,WBP2,SYNPO2,PRMT8,HIRA,WIPF1,KLC2,GPR158-AS1,REEP1,CSDE1,PRDM10,NAV3,LINC00632,GOPC,NETO2,SLC4A10" MicroRNA hsa-miR-338-3p:PITA hsa-miR-338-3p:PITA_TOP PITA 6.09E-36 3.42E-32 1.61E-35 1.48E-34 69 217 "TMEM132B,SNX30,ESYT2,MTUS1,SEMA6A,MAP4K3,ZBTB10,DDX3Y,ATP2B1,NOL4,DCAF5,CDK5R2,CACNB4,THSD7A,KIAA1549L,CNR1,CNTFR,RGS6,ST18,DGKB,SV2A,SRGAP3,G3BP2,DLG2,ABI1,DNAJB6,FRY,PLEKHA1,PAN3,AFF2,CHL1,CPLX2,EML4,GRIA2,FRMD3,NCKAP1L,BACH2,KCND2,KCNMA1,MAP2,NEUROD1,NOVA1,XRN1,PRKCB,TMEM255A,RGS7,ARHGEF10L,SEC61A2,ZFHX4,FBXW7,CPEB3,SMTN,RIMS1,MBD5,MYT1L,MYCBP2,LMO3,CLASP2,LARP4,PRRC2C,SYN2,TNFRSF1B,TSC1,CADM1,AMOT,TBC1D15,CADM2,RGS7BP,FZD3" MicroRNA hsa-miR-455-3p.1:TargetScan hsa-miR-455-3p.1 TargetScan 6.36E-36 3.57E-32 1.68E-35 1.55E-34 79 287 "FMNL2,ADORA2A,PWWP2A,OSBPL8,LTBP4,PPFIA3,DYNLL1,ATP2B1,BCL2L2,KALRN,RUNX1T1,CCNH,CACNA2D2,LHX2,KMT2C,NRXN1,CLTC,NIPBL,ARMC8,ARHGAP32,EARS2,RIMS3,CHRDL1,DLG3,DLG4,CDON,DRP2,PHC2,HEYL,CELSR3,APH1A,ETV1,PTK2B,ARFGAP2,B3GAT1,ATP8A2,RAB30,GPD2,GRB10,GRIK2,GRIK3,IL1RAPL1,MFSD2A,HAS2,GABARAPL2,RBPJ,SCRT2,KCND1,CLVS2,KCNJ4,KIF5A,MSANTD3-TMEFF1,MPP2,SAMD5,MYO6,PAX6,PDE3B,PIK3R1,PPP2R5E,PRKAB2,GAL3ST4,CYB561D1,ROBO1,SALL1,SCN2B,ARX,NTNG1,CDK19,DIP2A,PUM2,FRYL,FNDC5,RUSC1,RICTOR,INTS3,CSDE1,RTN4,CBLN2,CPNE4" MicroRNA hsa-miR-323b-5p:mirSVR_highEffct hsa-miR-323b-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.95E-36 3.90E-32 1.83E-35 1.69E-34 100 455 "BEND6,PPFIA1,SUGT1P4-STRA6LP-CCDC180,EIF4G3,ALDH7A1,ADAM23,MPDZ,CALB1,PTBP2,CAMK2B,METTL6,AIFM1,SYNGR3,CDC42,TIGD7,SYNPR,RAB33A,DNAJB5,SUMF2,SLC4A8,ST18,ZFYVE16,CEP170,DDX46,WDR20,TMTC1,MBNL2,CALCRL,ERBB2,CEP78,GORAB,FGFR3,TPK1,TUBGCP4,TNRC6A,GNAS,GRIK2,MUM1,NXPH2,INSM1,JAK1,KCNJ16,KCNMA1,KIF5C,LIMS1,ARHGAP12,ZNF667-AS1,MAP6,MARK1,MBNL1,SYT9,MXI1,NDP,NTRK2,OPHN1,SNTG1,PBX1,PLP1,PRIMPOL,MINDY2,APTX,PIGG,PTPRE,MSANTD2,SLC25A36,SETD5,ALG9,ROBO1,ITSN1,NLGN1,CCDC88A,SCMH1,MBD5,LMBRD1,SNRPN,ERC1,DBNDD2,NPAS3,CLASP2,CEP68,NSFL1C,FGD4,SYT1,FBXW11,ZEB1,TCF12,RALYL,ARHGAP9,LRRC8A,SEZ6L,TPM4,AMACR,FMN2,SPIRE1,PCDH15,ST7,UBE3B,KAT6A,FAM219B,NETO1" MicroRNA hsa-miR-150-5p:TargetScan hsa-miR-150-5p TargetScan 7.79E-36 4.38E-32 2.06E-35 1.89E-34 76 266 "METAP1D,PKP4,APC,GPAM,CDK13,MTMR9,N4BP2L1,CDK5R1,DST,CACNA1G,BSN,PTBP2,CAMK2G,CAST,CCNT1,DGKI,REPS2,CFL2,LETMD1,SEC31B,RIMS2,KIAA0087,ELMSAN1,KLHL3,NR1D2,DYRK1A,ABI2,PLXNC1,DENND4A,RCSD1,MRVI1,NBEA,MPP6,DKK3,GAB1,GABRA4,GABRG2,ATP8A2,GPR75,IL1RAPL1,CELF3,NXPH3,IGFBPL1,NEGR1,KCNB1,KCNN3,PIK3AP1,MDM4,MMP16,MDGA1,NEFM,NOVA2,NLGN3,FTO,PLXNB1,CNNM2,PIGG,PTPRB,PRRT2,FIGN,CYB561D1,RORB,RIMKLA,KCNIP1,SBF1,SCP2,ITSN1,CPEB4,SCN3B,PEG10,NFASC,FBXW11,FNDC5,MAP3K12,FAM47E,GAN" MicroRNA hsa-miR-936:PITA hsa-miR-936:PITA_TOP PITA 8.05E-36 4.52E-32 2.12E-35 1.95E-34 75 259 "CSMD3,FAM135A,DPP10,LRRC4C,API5,STX16,SCARB1,CFL2,MAP4K4,CNR1,SLC4A7,RBM39,SLC32A1,DOCK4,FRMPD4,MAML1,ZBTB24,KLHL3,ABI1,DRP2,TSPAN5,SH3GLB1,FAM13A,CALCRL,ETV1,FGF12,CAMSAP1,FAM49B,PHYHIPL,MEGF11,GABRB3,PCDH17,FAM222A,IGF1,KIF5A,SMAD1,MBNL1,AFDN,NEXMIF,NPTX1,GPR137C,GPR85,PIK3C2A,TRHDE,PROX1,PTX3,TMEM255A,SLC25A36,ATXN2,LRRTM4,TRA2B,HSPA4L,CPEB3,MAGI3,ABLIM3,CCDC88A,CPEB4,SORCS3,RBM26,CLASP2,COLGALT2,NKAIN2,ERBIN,SYT1,SYT4,CAMSAP2,TRIM2,SIRT1,HEY2,EMSY,EVI5,NAV3,PAK5,HNRNPA3,ADAMTSL3" MicroRNA hsa-miR-518a-3p:mirSVR_lowEffct hsa-miR-518a-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.31E-36 5.23E-32 2.45E-35 2.26E-34 112 563 "ACTN2,NDRG3,PLEKHG5,PSMG3-AS1,RNF150,OLMALINC,LRRC7,ALAD,CNTNAP1,APP,ARHGAP5,ASGR1,FUBP1,THSD7A,NGB,PRC1,CCPG1,SRSF11,SOCS6,NRXN1,QKI,SULT4A1,MAP4K4,ARHGEF6,SLC25A27,MYRIP,ZNF521,ANKRD44,CX3CR1,KCTD8,DAPK1,SIRPA,DGCR5,SRGAP3,DMPK,SLC29A4,CDON,EDN1,SGK2,SEMA3D,EIF1,MRPL37,EXTL1,IP6K2,NELFCD,SDCBP2,GFAP,PCLO,GRIK1,LINC00839,KLF12,AGBL5,HSD17B1,KCNJ11,LMO1,MOBP,MPP2,LYRM9,MYO6,RTL5,NME4,SLC11A2,NRGN,NTRK2,OPA1,BEST3,PFKFB2,SSH1,MAPKAP1,GRAMD1C,ELOVL2,PXK,PTN,SH3TC2,FAT4,OXR1,RADX,GTDC1,SLC25A36,CCDC25,WLS,FOXRED2,SCN2B,SCN3A,HSPA4L,BCAN,SHANK2,CPEB4,IFT122,MAPKBP1,PDZRN3,SON,KDM3A,ADHFE1,C12orf76,AGTPBP1,MGRN1,ZEB1,RIMBP2,C5orf64,TPM3,RGMB,TRIO,TSC1,UCHL1,CELF4,WNK1,DNALI1,MPPE1,PDSS2,KAT6A,FRMD6" MicroRNA hsa-miR-1184:PITA hsa-miR-1184:PITA_TOP PITA 1.07E-35 5.99E-32 2.81E-35 2.59E-34 72 239 "ARID1A,TAOK1,ANK1,MAP4K3,ARHGAP5,NUMB,ATP2B3,ADGRB3,CABP7,CAMK2G,TPP1,SH2B1,CREB5,FEZ1,NCAN,APPL1,CTNND1,RIMS3,MAML1,LYPD1,CHRDL1,DLG2,TENM1,TOMM40L,OLFM1,GABRB3,CAB39,RND1,GNAO1,CIT,BACH2,AGFG1,KCNN3,MDGA1,NFIX,NPTX1,PDE4D,ENPP2,PIK3R1,PKIA,BCAS3,MTMR10,TMEM260,USP47,BSDC1,DUSP15,TTLL7,ZFHX4,SETD5,SCN3A,SCAF8,CPEB3,SMARCE1,RCOR3,SOX11,HECW1,ERC1,PEG10,CAMTA1,TCF4,SATB2,TNS2,DICER1,HEY2,NSD2,TRIM9,ZFAND5,EMSY,SLC17A7,WNK3,PDSS2,HNRNPA3" MicroRNA "TGCACTG,MIR-148B:MSigDB" "TGCACTG,MIR-148B:MSigDB" MSigDB 1.09E-35 6.12E-32 2.87E-35 2.64E-34 79 289 "ADCY2,PLEKHH1,HECW2,PCDH10,ANK2,MIER1,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,CDK5R1,SYNJ1,CABP7,CAMK2A,CANX,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,ST8SIA3,MED12L,PRKAG2,NEURL4,GAP43,DNER,ARFIP1,PPARGC1A,TNRC6A,KDM2B,GPM6A,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,POU3F2,KANSL1,MDGA2,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,CHD9,FBXO11,BTBD3,EPN2,LRRC55,CPEB4,USP33,SOX11,CDK19,SYT1,ARHGEF12,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,NSD2,KLC2,RICTOR,USP32P2,RGMA,SNX27,JPH3" MicroRNA "TGCACTG,MIR-152:MSigDB" "TGCACTG,MIR-152:MSigDB" MSigDB 1.09E-35 6.12E-32 2.87E-35 2.64E-34 79 289 "ADCY2,PLEKHH1,HECW2,PCDH10,ANK2,MIER1,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,CDK5R1,SYNJ1,CABP7,CAMK2A,CANX,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,ST8SIA3,MED12L,PRKAG2,NEURL4,GAP43,DNER,ARFIP1,PPARGC1A,TNRC6A,KDM2B,GPM6A,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,POU3F2,KANSL1,MDGA2,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,CHD9,FBXO11,BTBD3,EPN2,LRRC55,CPEB4,USP33,SOX11,CDK19,SYT1,ARHGEF12,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,NSD2,KLC2,RICTOR,USP32P2,RGMA,SNX27,JPH3" MicroRNA "TGCACTG,MIR-148A:MSigDB" "TGCACTG,MIR-148A:MSigDB" MSigDB 1.09E-35 6.12E-32 2.87E-35 2.64E-34 79 289 "ADCY2,PLEKHH1,HECW2,PCDH10,ANK2,MIER1,MARCH3,CHRD,NCOA1,ATP2A2,BCL7A,CDK5R1,SYNJ1,CABP7,CAMK2A,CANX,USP6,NOG,CFL2,SRSF11,PLAA,QKI,AKAP7,CLOCK,CSF1,SNPH,ELMO1,WDR20,ST8SIA3,MED12L,PRKAG2,NEURL4,GAP43,DNER,ARFIP1,PPARGC1A,TNRC6A,KDM2B,GPM6A,RNF165,BACH2,AGFG1,STXBP5,MITF,CNOT4,NPTX1,SEPT4,POU3F2,KANSL1,MDGA2,ROBO1,ROBO2,RORB,PRR5L,RXRA,ATXN1,CHD9,FBXO11,BTBD3,EPN2,LRRC55,CPEB4,USP33,SOX11,CDK19,SYT1,ARHGEF12,DICER1,ZFPM2,AP4E1,TRPM2,TRPS1,NSD2,KLC2,RICTOR,USP32P2,RGMA,SNX27,JPH3" MicroRNA hsa-miR-1827:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-35 6.80E-32 3.18E-35 2.93E-34 140 837 "SDE2,ABCF1,AS3MT,XKR4,NDRG3,KLHL32,PLEKHG5,ELFN2,ADD2,SLC24A4,TXNDC16,LTBP4,TRMT9B,APAF1,CPNE5,AQP6,CDC14B,KIAA1614,SFMBT2,ASPA,ATM,ZNF583,DDR1,ZNF555,PTBP2,CANX,BRSK2,ISPD,SLC16A4,C1orf52,CFL2,GPR37L1,NRXN3,LETMD1,AKAP5,MFSD4A,SLC35F1,IPCEF1,USP6NL,SEC14L5,PHF19,KIAA0513,TMEM170A,DNAL1,ELMSAN1,SGSM2,DNAH9,SLC29A4,E2F6,SYT15,HEYL,RASA4,IRAK4,MRNIP,MTSS1L,VPS26C,ANKMY1,ZNF585B,ZNF589,PCYOX1,ATP13A4,TRMO,MSANTD4,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,ZNF638,GNG4,KIF3A,BVES,DDX19B,SCRG1,AGBL5,ZNF546,IBA57,KLHL23,SMAD9,MAP4,MATN3,MDM4,PPM1L,CCDC80,MXI1,NBL1,SLC11A2,NUCB1,PDGFRA,CCSER2,PLEC,PLXNB1,RETREG2,MTMR10,PTPRE,TMEM145,ZNF844,QDPR,PLEKHB2,ZNF793,MSANTD2,SETD5,GSTCD,SNX22,PTGR2,SALL1,SLC30A10,IL17RB,SH3BP2,MYO18A,MAGI3,SLC2A5,LIMS2,ATF7IP,SCN3B,KIF1B,IQSEC2,CDK19,LHPP,ZSCAN29,FAM168A,ACSBG1,ZC3H4,FAM208A,USP22,AKNA,AHCYL2,NACC2,TPM3,PPIL6,SSBP2,TUBB2A,ZNF70,SNX27,MPPE1,PARP11" MicroRNA hsa-miR-103-as:mirSVR_highEffct hsa-miR-103-as:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.25E-35 7.04E-32 3.30E-35 3.04E-34 100 458 "ADORA3,PTCHD1,MTUS1,HACE1,BEGAIN,PHF12,SUGT1P4-STRA6LP-CCDC180,NUMB,ATP1A1,TTLL9,CFLAR,ZNF501,AIFM1,HECTD1,TMEM155,FAM171B,RBM39,CS,RGS6,NRSN1,MAML1,DDX46,ALKBH8,NTM,PDCD6IP,GNE,PHF20L1,KCTD3,RGS17,RTN3,RGPD5,PSD2,NBEA,RASL10A,GART,KIAA1841,GHR,BRD8,CCDC184,CNTRL,GRIA2,GRIA4,RASSF8,HMGCL,IDH3B,DOCK7,KCND2,KCNJ16,KIF2A,SMAD1,ZNF667-AS1,MAT2A,AQP11,NAP1L2,GNG2,PPARA,GRAMD1C,RELN,VPS13C,SNRK,UHRF1BP1,BDNF-AS,ZCWPW1,RDX,SEC61A2,SNX22,NEK11,GLDN,KCNIP2,SAFB,SATB1,TNFRSF19,SHC4,HKDC1,FNDC3A,ST3GAL3,RPH3A,EPC1,SNAP25,UNC80,ITPRID2,ZSCAN29,PRRC2C,CAMTA1,CUX2,TRIM2,RPGRIP1L,MTMR14,TJP1,TMOD1,SEZ6L,TPM2,PRMT8,CADM1,KCNT2,PCDH15,MVB12B,PDSS2,MRPL47,JMJD1C" MicroRNA hsa-miR-125a-5p:PITA hsa-miR-125a-5p:PITA_TOP PITA 1.39E-35 7.82E-32 3.66E-35 3.37E-34 83 320 "ABHD6,LRFN2,MTUS1,USP37,SLC4A4,ADGRB1,MTMR3,NIPA1,BSN,DIRAS1,FMNL3,ARHGEF1,SCARB1,SULT4A1,ZNF385A,HINFP,NCOR2,NCAN,FAM131B,TM9SF4,PHYHIP,IST1,IP6K1,ELMSAN1,RUSC2,ZC3H11A,DTNB,ABCC5,FAM135B,PHC2,CNNM1,EGR3,ANKRD13B,ERBB4,ZNF589,SEMA4D,GGT7,LOXL3,GRB10,SPACA9,MAN1B1,HRH3,HMGCR,SLC6A17,KCNA1,LIFR,ADAM11,MEIS2,MSI1,MYT1,ZC3H12B,NEFM,CHAMP1,CAMKV,RETREG2,DRAM2,PPP2R5C,SH3TC2,KCNIP3,ATXN1,SCN2B,CPEB3,PPP4R3A,ABTB1,SOX11,SPTB,ZSCAN29,SATB2,DICER1,NPL,TRPS1,SLC35A4,KLC2,CRB2,TMEM198,SLC17A7,SNX27,WIPF2,GOPC,VANGL2,MSRB3,SOCS4,SLC4A10" MicroRNA hsa-miR-125b:PITA hsa-miR-125b:PITA_TOP PITA 1.39E-35 7.82E-32 3.66E-35 3.37E-34 83 320 "ABHD6,LRFN2,MTUS1,USP37,SLC4A4,ADGRB1,MTMR3,NIPA1,BSN,DIRAS1,FMNL3,ARHGEF1,SCARB1,SULT4A1,ZNF385A,HINFP,NCOR2,NCAN,FAM131B,TM9SF4,PHYHIP,IST1,IP6K1,ELMSAN1,RUSC2,ZC3H11A,DTNB,ABCC5,FAM135B,PHC2,CNNM1,EGR3,ANKRD13B,ERBB4,ZNF589,SEMA4D,GGT7,LOXL3,GRB10,SPACA9,MAN1B1,HRH3,HMGCR,SLC6A17,KCNA1,LIFR,ADAM11,MEIS2,MSI1,MYT1,ZC3H12B,NEFM,CHAMP1,CAMKV,RETREG2,DRAM2,PPP2R5C,SH3TC2,KCNIP3,ATXN1,SCN2B,CPEB3,PPP4R3A,ABTB1,SOX11,SPTB,ZSCAN29,SATB2,DICER1,NPL,TRPS1,SLC35A4,KLC2,CRB2,TMEM198,SLC17A7,SNX27,WIPF2,GOPC,VANGL2,MSRB3,SOCS4,SLC4A10" MicroRNA hsa-miR-3130-3p:mirSVR_highEffct hsa-miR-3130-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-35 8.80E-32 4.11E-35 3.79E-34 98 442 "XKR4,FMNL2,KIAA1324,C1QTNF3,LRRC7,USP28,SUGT1P4-STRA6LP-CCDC180,PHYHD1,B3GALT2,CACNA1G,CBR1,INA,CD38,RAB33A,QKI,HECTD1,BTF3L4,SLC35F1,FAM171B,TENM4,ECE2,DCAF8,LONRF1,MATR3,ZEB2,PLPPR4,NTM,SGSM2,DYNC1I1,EDN1,ELN,HSD17B14,ZNF549,TMEM74,FCGRT,PRMT5,WDR83,HVCN1,GABRA1,ARPP21,MSTN,CLASRP,GSTT2,WIF1,HMGCL,ZDHHC15,IRF8,LRRTM3,KCNK2,KCNMA1,LAMP2,STMN1,PAXBP1,MEIS1,KCTD6,CCDC13,NELL2,OTOGL,PDCD2,PLCB2,NECAB2,POLG,ZCWPW1,MYH14,ELP2,RPL15,FBXW7,ACER3,ABCA11P,TRA2B,RASA3,ITSN1,SLC1A3,SLC20A2,ATF7IP,SMARCA4,LIMCH1,C11orf87,TAB2,SYN2,CAMSAP2,TCF7L2,PCDHB9,LEFTY2,MTMR14,ERCC6L2,TNR,RUSC1,RPL7L1,BCL2L13,MGAT5B,ZIC3,PROCA1,CA10,CSDE1,PHTF2,RNF170,IFT88" MicroRNA hsa-miR-484:Functional MTI Functional MTI miRTarbase 1.64E-35 9.22E-32 4.31E-35 3.97E-34 145 891 "ABCF1,ACLY,ARID1A,ADAR,AP1B1,AMPD2,APLP1,GPAM,APP,PDXK,ARHGDIA,ATP1A1,ATP1A2,ATP2A2,DST,BSN,CAMK2D,SPAG9,CBR1,CERS5,AIFM1,LONRF2,CDC42,TAOK2,KMT2C,COG1,CLTC,TMEM184B,AKAP7,PREPL,ENTPD4,RBM39,SH2B1,RNF14,NCOR1,ELMSAN1,BLOC1S6,POM121,G3BP2,SEC16A,EXOG,ATN1,FIS1,EFNB3,SUGP2,EIF4G2,TNK2,DCTN4,DMTN,RTN3,WAC,TUBA1B,TOMM40L,MED12L,KIAA1109,SUCO,SEMA4D,GART,TUBGCP4,SRCAP,AHDC1,TNRC6A,MSL3,GLUL,PRRC2B,GPR26,CECR2,GRIA4,ZBTB45,HNRNPK,HSP90AA1,IPO5,STMN1,FGFBP3,GPR155,MAN2A2,MAP4,MAT2A,MEIS1,MPP2,GIT1,MTR,MYO5A,HNRNPM,NASP,NEK1,NME4,SLC11A2,NUCB1,OCRL,TMOD2,PKD1,ZFYVE21,PKM,NLE1,RC3H2,EXOSC10,MBOAT7,POLG,RFX5,C12orf49,ELP2,PTGR2,CASC3,PUF60,FUZ,NUBPL,URGCP,DHX30,KANSL3,SLC6A8,SEPHS1,ATF7IP,ANKRD36,KIF21B,ZSWIM8,CLUAP1,PEG10,ZNF621,DIP2A,GANAB,NSFL1C,JMJD6,SUPT5H,SYNE2,ATP11A,PDLIM2,ZEB1,CBX5,DCBLD1,HSPBP1,TUBB2A,SGK3,CADM1,UBTF,CCDC136,TBC1D15,KLC2,POLR3H,SPIRE1,UPF3A,PMEPA1,SLC38A1,HNRNPA3,NHSL1" MicroRNA hsa-miR-618:PITA hsa-miR-618:PITA_TOP PITA 1.82E-35 1.02E-31 4.78E-35 4.40E-34 76 269 "NLGN4X,CDC42BPA,DPP10,ZBTB10,NOL4,JAZF1,MAP7,USP6,MAGI1,SRSF11,FOXN3,CHM,CLTA,CNN3,BTF3L4,RCHY1,NCOR1,CNTNAP2,HDAC4,SPOCK2,YTHDC1,MAMLD1,SEC24B,FGF13,FGFR3,PHYHIPL,DNER,PCDH11X,GPM6A,LPAR4,GRB10,KLF12,NEGR1,C5orf24,KIF5C,MARK1,MID1,NEXMIF,NFIX,NOVA1,HCN1,OPCML,GPR85,GNG2,LRP12,PACSIN1,TNPO2,MED1,RAP1GDS1,FIGN,ZC3H14,MCMBP,SALL1,ATXN1,SCN2A,SOX6,CPEB3,FHOD3,PPP4R3A,TET1,FNBP1,SOX11,SP4,KDM4C,ZNF423,SYT1,DMXL2,HHIP,TJP1,TPD52,WIPF1,ZNF711,CELF4,PMEPA1,RNF146,SOCS4" MicroRNA hsa-miR-553:mirSVR_highEffct hsa-miR-553:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.91E-35 1.07E-31 5.00E-35 4.60E-34 93 401 "SDE2,NBAT1,SORCS1,OSBPL6,AMPD3,OGT,CDC42BPA,APP,ARNTL,MARCH3,SLC4A4,PTBP2,METTL6,CCNH,SEPT7,CDC42,CDH10,SYNPR,NRXN3,IGFBP7-AS1,HECTD1,FHL5,PCYT1B,SLC4A8,GAL3ST1,DCAF4,TM9SF4,C2CD2L,USP3,DPH1,AASDH,RASGRP1,C8orf37,PAN3,DNAJC27,ZIC4,SCML2,ZSCAN30,AMOTL2,FOXO3,NPTN,NEU3,ARFIP1,GHR,PPARGC1A,TNRC6A,GPM6B,TDRKH,GPR12,KIF3A,ELOVL5,ZNF678,LAMP2,NCOA7,SMAD9,MAOB,JAKMIP3,GPR88,PDE4D,NALCN,MED1,PPP2R2B,SIDT1,SPDL1,TMEM260,PTPRG,PRRT2,GTDC1,CLIP1,AMER2,MIR124-2HG,FNIP1,SH3BGR,SHC4,NLGN1,FAM81A,PPP4R3A,SLIT1,MBD5,NXT2,SYPL1,CUX2,RPRM,FAM181B,VLDLR,NSD2,FMN2,ZNF138,SMARCAD1,CA10,FIP1L1,TMEM163,HNRNPA3" MicroRNA hsa-miR-1228*:mirSVR_lowEffct hsa-miR-1228*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.36E-35 1.32E-31 6.18E-35 5.69E-34 106 514 "ACHE,KLHL32,KIAA1211,KIAA1324,AMPD2,ANK3,SEMA7A,PPFIA4,SUGT1P4-STRA6LP-CCDC180,DGKZ,ASGR1,ATM,SNAI3-AS1,GPC2,USP2,ARHGEF1,CBFA2T2,SYNGR3,CDC27,ASIC3,SYNPR,NRXN3,CLU,AKAP7,SUMF2,SLC35F1,SNCAIP,HDAC4,SEC16A,DMPK,DPH1,CACNG7,ELN,CACNG3,SCML2,RACK1,FGF1,BAIAP2,PRKAG2,POLK,C1orf61,RGPD5,FYN,LRRC37A6P,CPLX1,NTNG2,STARD3,ADAMTS13,GRIN2D,LINC01089,FRMD5,FAM95B1,SOWAHA,ZNF678,KHK,IPO5,JAKMIP3,MT3,MYH6,IGSF11,LOC100128398,ZNF713,PKD1,ZFYVE21,MBOAT7,VSTM2L,BCAS3,RGS3,RGS12,PRIMA1,KCTD17,TMLHE,YY1AP1,RPL15,KCNIP1,NCBP3,SEMA6D,HOGA1,TRIM46,NTNG1,AMBRA1,URGCP,SMTN,LIMS2,SLC6A9,LGI3,SNRPN,SOX10,ZSWIM8,ZC4H2,SSPO,SLC37A2,MLST8,ANO4,NEU4,TPCN2,RELL2,PDSS1,BEST1,LMF1,CLIP2,ATP6V0E2,PCBP4,RTN4,CASC15,FAM219B" MicroRNA hsa-miR-593:PITA hsa-miR-593:PITA_TOP PITA 2.46E-35 1.38E-31 6.43E-35 5.92E-34 67 208 "ELFN2,DSCAML1,ZNF608,PCDH19,DPP10,CNTNAP1,DYNLL1,BCL2L2,NRP2,THSD7A,NOG,HECTD1,SLC25A27,NRG2,ZEB2,SRGAP3,DLG2,DLG3,EGR3,RGS17,PAN3,EYA1,FGF11,AGAP3,FOXO3,USP21,ST6GALNAC3,GABRB3,CPLX2,GPD2,GRID1,PTPN5,CELF3,NKD1,LRRTM1,OLFM3,MEF2C,BLOC1S2,NTRK3,KSR2,ZNF827,CDK18,SETD5,KCNIP1,SCN2A,SCAF8,CHD9,WDR37,WDR47,MBD5,LHFPL4,ERBIN,NCDN,SEMA4A,CAMTA1,TCF4,SATB2,TCF12,FRYL,RBFOX2,SEZ6L,NR2C2,KCNE5,SLAIN1,PITPNB,SYNC,KAT6A" MicroRNA hsa-miR-193b-3p:Functional MTI Functional MTI miRTarbase 2.57E-35 1.44E-31 6.73E-35 6.20E-34 141 853 "ACTN1,ARID1A,ESYT2,HACE1,NT5C3B,PDXK,ATP1A1,STX16,ALDH7A1,BARD1,BLM,C5,BTRC,SPAG9,CBS,KYAT1,ARHGAP33,TJP2,C2CD2,CS,TENM4,PHF19,HP1BP3,KBTBD11,DLX1,DPH1,FARSB,E2F6,TMTC1,ABI2,PLXNC1,ASB3,EIF1,COQ7,EFS,GMPR2,TUBA1B,TUBB3,TAOK3,FGF11,TMEM164,ANKFY1,NSG1,STAG2,KIAA1841,AHDC1,TXNL4A,CBX1,PSRC1,PRRC2B,RAPGEF1,CACFD1,PSIP1,ATOH8,PACSIN2,ARHGAP19,HMGB1,HMGCR,HSPA1L,GAREM2,ITPKA,SLC35G1,KIT,STMN1,NAT8L,ZFYVE27,MAT2A,MRPL42,DBNL,MTR,MYO5A,HNRNPM,NF1,NFIA,NME4,NUCB1,NUCB2,OPHN1,PFKP,EXOSC10,PPP2R5C,CEP41,EPDR1,MAPK8,SNRK,PTPRG,MSANTD2,MORC4,UBR7,MYH14,C12orf49,RTKN,RMI1,CASC3,SFPQ,MYO18A,SHMT2,SEC31A,CLSTN1,ZNF365,DHX30,SEPHS1,ELMO2,EFHD1,EMC1,UNC5B,PEG10,KIF1B,ZBTB43,INKA2,SULF2,SYNE2,DNAJC9,TACC1,TCF7L2,ATP13A2,ZMAT3,TGFBR3,MTMR14,LRRC8A,TNFRSF1B,ZNF384,NEIL2,AMACR,RUSC1,TSC1,RPL7L1,UCHL1,PITPNB,VAV2,NSD2,XPO1,WNK1,RGMA,CIAPIN1,TRIM16L,KAT6A,NUP214,NLRP3,AAAS,RNF146" MicroRNA hsa-miR-18b*:mirSVR_highEffct hsa-miR-18b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-35 1.54E-31 7.15E-35 6.59E-34 87 354 "ACTN2,BRAP,SUGT1P4-STRA6LP-CCDC180,ATM,SLC4A4,BBS2,LINC00906,PTBP2,CRLF1,IGFBP7-AS1,TPP1,ARMC8,RCHY1,C2CD2,OSBPL3,PDE4DIP,GREB1,TMEM170A,DLG2,SLC12A6,KRBA2,SNX29,VPS13B,LRRC17,SLC9B2,IP6K2,JKAMP,MEGF11,BRD8,RAB30,FERMT2,GPD2,LILRA1,GRIA1,GRIA2,GRIA4,GRIN1,GRM5,GRM7,KLF12,ARHGAP12,MAT2A,NOVA1,SLC11A2,NUCB2,NUMA1,P2RY1,CDK14,FAM218A,A2ML1,PRRX1,PRKACB,SYTL2,SNRK,BDNF-AS,ZSCAN32,PTPRG,ARHGEF10L,ROBO2,SPIN3,SGK1,CNKSR2,SLC6A11,SLC9A5,SLC12A2,SLC15A2,SLIT1,CXXC4,USP33,ENKUR,NFASC,CLSTN2,STAU1,TMEM150C,ANKRD12,TBCEL,ZFP90,PMS2CL,DDHD1,RASD2,AMACR,PLPPR2,FSTL5,DNALI1,NAV3,CERS6,FAM198A" MicroRNA hsa-miR-425-5p:TargetScan hsa-miR-425-5p TargetScan 2.93E-35 1.65E-31 7.66E-35 7.06E-34 66 202 "RNF150,AMPH,ANK3,PHF12,ATP1B3,N4BP2L1,CALM1,RUNX1T1,AIFM1,DGKI,CFL2,RAB3C,CLCN4,HECTD1,RNF14,CTNND1,NOS1AP,MATR3,MAML1,DGKG,PITPNC1,ELMSAN1,CDON,CPEB2,DPYSL2,DNAJB6,DYRK1A,FAM135B,HIPK3,ELAVL4,RGS17,DNAJC27,GABRB3,CAB39,ATP8A2,GRM1,IL1RAPL1,ARHGAP36,AGFG1,IGF1,ITPKB,CLVS2,MEF2C,MEIS1,GIT1,NCAM1,PAK3,PCMT1,PDE3B,SDK2,PPP3CA,PTCH1,ANKHD1,PTPRN2,GTDC1,ALG9,EPN2,EPC1,KIF21B,C3orf70,KAT6B,RGMB,PRDM8,CAB39L,HNRNPA3,NETO1" MicroRNA hsa-miR-186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-35 1.74E-31 8.08E-35 7.44E-34 99 454 "SYN3,XKR4,ZNF578,ATM,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,CACNA1A,CACNB2,KALRN,VXN,ZBED1,DIS3L,PLAA,DNAJB5,COL9A2,ENTPD4,CRY2,NCAN,SOCS5,PYGO1,DNAL1,SPATA2,KLHL3,RABGAP1L,DMD,SLC12A6,GNE,IRAK4,C8orf37,MRPL37,TLR7,ECSIT,TBC1D16,GTF2IRD2,FGF1,AMOTL2,IP6K2,ANKFY1,APOPT1,FUT9,TRAF3IP2,KIAA1841,SRCAP,FREM1,CRCP,RAB30,PTPRT,RNF165,MFSD2A,HAS2,HMGB1,OPALIN,ATCAY,NKD1,KCND3,SFXN5,GPR155,PPM1L,OLR1,P2RX7,PAH,KCNK10,TMOD2,PIK3C2A,PLCL1,SMIM7,ZNF426,PTAFR,OCIAD1,ZSCAN2,C12orf49,FOXRED2,DRAXIN,SCN2B,HSPA4L,SH3BP2,SLC8A3,ATF7IP,ZHX3,SP2,POGZ,STAC2,WWC1,KIAA0930,SATB2,GPRIN3,ZMAT3,PARD3,RUNDC3B,TOM1L2,ZNF708,ZNF70,ZBTB16,MPPE1,VANGL2,GAN" MicroRNA hsa-miR-675:mirSVR_lowEffct hsa-miR-675:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.36E-35 1.89E-31 8.79E-35 8.10E-34 94 412 "SLC12A5,TAOK1,MRTFA,SUGT1P4-STRA6LP-CCDC180,ARNTL,MARK4,ATP2B2,LINC00847,CA4,CAMK2B,TRIM41,SYT6,BRSK2,ASIC3,TAOK2,NRXN3,PPT2,FADS2,MAP4K4,IGLON5,CNTFR,LETMD1,ZNF385A,HINFP,MICAL2,RUBCN,HDAC9,DLG4,HS3ST2,SLC29A4,GNE,EPB41L2,SPEG,RACK1,OLFM1,FGF13,SCARA3,AGAP2,SEMA4D,SORBS1,DLL3,BRPF3,SIGLEC8,ATP8A2,STARD10,RNPS1,STARD3,AP4S1,TLX1,IRF8,KCNK1,MYO7A,ALDH1L2,NRGN,NUMA1,CDK18,PKD1,PLIN1,EPN1,PLXNB3,C11orf49,MAPK4,BCAS3,PYGM,GTDC1,UBR7,RGS7,SEC61A2,SNX22,ZNF568,PEAR1,MYO18A,WDR37,SLC6A8,SLC8A3,SLC22A4,CPEB4,MYO16,SSTR1,SSPO,AJAP1,JMJD6,SYN1,PDLIM2,WDR7,PCDHB9,ITGB3BP,PPIL6,SLC35A4,NDRG4,LINC02210,URM1,TMEM163,NUP214" MicroRNA hsa-miR-892c-3p:TargetScan hsa-miR-892c-3p TargetScan 3.59E-35 2.02E-31 9.38E-35 8.64E-34 72 243 "ADARB2,ELFN2,GALNT13,RNF157,ADD3,ANK2,ATP2B1,FUBP1,CACNA2D1,CAMK2G,CANX,DCLK1,CACNA2D2,CHN1,FHL5,BTF3L4,FRMPD4,MATR3,HP1BP3,GRIN3A,DYRK1A,ABI2,ELAVL2,EPB41L1,EPS8,ERBB4,AMOTL2,HPCAL4,MSANTD4,PCDH17,RAB30,GPR22,RAPGEF1,GRM3,PACSIN2,KLF12,AGFG1,IGF1,IL6ST,KCNB1,KCNN3,KIT,NCOA7,NAT8L,LDLRAD3,MEF2C,P2RY1,PDE4D,GPR173,POU6F1,PPP3CB,PKN2,RAD52,SEC61A2,ROBO2,RIMKLA,FBXO11,C11orf87,FGD4,ANKRD28,CNTN2,MGRN1,C5orf64,RGMB,FLRT2,ANKS1B,EVI5,NAV3,C12orf4,RGS7BP,CERS6,MSRB3" MicroRNA hsa-miR-452-5p:TargetScan hsa-miR-452-5p TargetScan 3.59E-35 2.02E-31 9.38E-35 8.64E-34 72 243 "ADARB2,ELFN2,GALNT13,RNF157,ADD3,ANK2,ATP2B1,FUBP1,CACNA2D1,CAMK2G,CANX,DCLK1,CACNA2D2,CHN1,FHL5,BTF3L4,FRMPD4,MATR3,HP1BP3,GRIN3A,DYRK1A,ABI2,ELAVL2,EPB41L1,EPS8,ERBB4,AMOTL2,HPCAL4,MSANTD4,PCDH17,RAB30,GPR22,RAPGEF1,GRM3,PACSIN2,KLF12,AGFG1,IGF1,IL6ST,KCNB1,KCNN3,KIT,NCOA7,NAT8L,LDLRAD3,MEF2C,P2RY1,PDE4D,GPR173,POU6F1,PPP3CB,PKN2,RAD52,SEC61A2,ROBO2,RIMKLA,FBXO11,C11orf87,FGD4,ANKRD28,CNTN2,MGRN1,C5orf64,RGMB,FLRT2,ANKS1B,EVI5,NAV3,C12orf4,RGS7BP,CERS6,MSRB3" MicroRNA hsa-miR-1286:mirSVR_highEffct hsa-miR-1286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.05E-35 2.27E-31 1.06E-34 9.72E-34 107 526 "FAHD2CP,GPR158,KIAA1324,CNIH2,EPB41L5,ALS2,BCAS1,TNRC6C,PLA2G4C,ASPH,CHRD,SLC2A11,CACNA1A,CALB2,KALRN,DGKI,CDH10,DLGAP1,TIGD7,CFL2,RAB3C,DGCR9,NIPBL,CNR1,LETMD1,SEC24C,PDE4DIP,DOCK4,GAPVD1,C8orf34,HP1BP3,DNM1,USP3,DNAJB6,DYRK1A,DNM1L,RBM12,YAF2,KMT5B,ABI2,TMEM132E,ELAVL2,LRRC17,F8,FGF14,SYNCRIP,IQCG,TMEM107,GABRA1,ZMYND11,GAP43,PCDH17,GNAS,TDRKH,PTPN5,MFSD2A,IRAK3,HNRNPK,KCNJ11,KCNK1,GATD1,PIK3AP1,MBD1,MYO9A,PABPC1L2A,TCEAL5,NAP1L2,PCSK5,PIK3C2A,ST8SIA5,SMOX,PLP1,HYDIN,RAD52,ZDHHC14,TRIM68,PRRT2,DCUN1D2,ARMC5,RORB,FAM182A,CASC3,SH3GL3,NTNG1,FBXO11,DHX30,CPEB4,CDK5RAP2,SMARCD3,SON,MYCBP2,ZNF423,PRRC2C,VAMP1,SLC37A2,SYT4,TAL1,CNTN2,WDR7,PCDHB7,TEX15,FAM200B,ARL10,CHST5,SLC35A4,WNK3,DNAH10" MicroRNA hsa-miR-1280:mirSVR_lowEffct hsa-miR-1280:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.28E-35 2.40E-31 1.12E-34 1.03E-33 89 372 "PNMA8B,SEMA7A,PPFIA3,AQP6,MIER1,CDK10,RGS20,CAPRIN2,SLC2A11,ADAM15,KALRN,CH25H,ENTPD6,CDH2,ZMYM4,CCPG1,CHGB,PLAA,NRXN2,CLTA,HECTD1,SLC25A27,NCOR2,CTNND1,HDAC4,DGKG,TOMM20,DGCR5,SPOCK3,DNAH9,DTNB,DNM1L,SGK2,ENPP6,RABEPK,IP6K2,NPTN,MEGF10,ARPP21,GCK,ALDH1L1,KIRREL3,PLCD4,ADAMTS13,RNFT2,FRMD3,USP51,CPT1C,HES5,C2CD4C,KIF5A,MAT2A,MATK,GIT1,STK32C,ZNF92,NFIX,NTRK3,NUCB2,ZDHHC22,ZFYVE21,PCDHB17P,PRPSAP2,PSMD13,TMLHE,RTN1,PRCD,KIF21A,PAAF1,FAM214B,KIF1B,RBM26,STX1A,AJAP1,MLC1,NUDT10,SYPL1,TMEM151B,HIF3A,GALNT17,TNR,UBTF,LMF1,ZBTB14,EML6,MAP3K12,PRDM2,STMN4,RNF146" MicroRNA "GACTGTT,MIR-212:MSigDB" "GACTGTT,MIR-212:MSigDB" MSigDB 4.78E-35 2.68E-31 1.24E-34 1.15E-33 58 154 "OSBPL8,SEMA6A,PCDH10,PHF12,SEMA4G,TMEFF1,FUBP1,PTBP2,LRRFIP1,LARGE1,CFL2,CREB5,ARHGAP32,ELMSAN1,POM121,SRGAP3,DUSP9,PHF20L1,KMT5B,NCALD,OLFM1,MEX3B,FOXO3,C1QL1,CBX1,TJAP1,KCNA6,KCNK2,MMP16,HNRNPM,NFYA,NOVA1,CDK14,MAPKAP1,PPP2R5C,RDX,PRRT2,GTDC1,RFX3,ATXN1,SCN3A,SOX6,BCAN,SLC6A1,LRRC55,SEPHS1,BTBD7,SOX5,SOX11,NMNAT2,MYCBP2,TRIM2,SIRT1,NEIL2,SGK3,NDRG4,CSDE1,FXR1" MicroRNA "GACTGTT,MIR-132:MSigDB" "GACTGTT,MIR-132:MSigDB" MSigDB 4.78E-35 2.68E-31 1.24E-34 1.15E-33 58 154 "OSBPL8,SEMA6A,PCDH10,PHF12,SEMA4G,TMEFF1,FUBP1,PTBP2,LRRFIP1,LARGE1,CFL2,CREB5,ARHGAP32,ELMSAN1,POM121,SRGAP3,DUSP9,PHF20L1,KMT5B,NCALD,OLFM1,MEX3B,FOXO3,C1QL1,CBX1,TJAP1,KCNA6,KCNK2,MMP16,HNRNPM,NFYA,NOVA1,CDK14,MAPKAP1,PPP2R5C,RDX,PRRT2,GTDC1,RFX3,ATXN1,SCN3A,SOX6,BCAN,SLC6A1,LRRC55,SEPHS1,BTBD7,SOX5,SOX11,NMNAT2,MYCBP2,TRIM2,SIRT1,NEIL2,SGK3,NDRG4,CSDE1,FXR1" MicroRNA hsa-miR-661:mirSVR_highEffct hsa-miR-661:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.54E-35 3.11E-31 1.44E-34 1.33E-33 103 492 "ASPHD1,DSCAML1,AP2A2,BCAR3,PCDH10,LCORL,PHF12,APBA2,APC,SEMA4G,RGS20,CAPRIN2,NCOA1,RIPK1,ADAM23,CACNA1D,LDB2,METTL6,CDH8,CHRM1,CLTA,COL9A2,LETMD1,CRYBB1,CSF2RA,SEC24C,MICAL2,GREB1,CFAP61,BOC,ZEB2,KIAA0753,SNAP91,FAM107B,DNM1,MED12,EPHB1,GMPR2,FGF11,SPECC1,USP21,JPH4,TUBGCP4,GFAP,MALT1,COPS8,GPD1,RNF165,CELF5,SOWAHA,IL6ST,ZNF678,KCNB1,KCNJ10,KIF5A,LIMS1,PAXBP1,SMAD1,PIK3AP1,ADAM22,MYH6,NCAM1,PAK3,PDYN,ZNF655,FAM218A,SLC36A4,PPARA,PKN2,DIRAS2,STK32A,RAD51D,RASGRF1,KLHL11,RNF220,RIC8B,RPRD1A,KCNIP2,RXRG,FAM182A,DGLUCY,SCP2,TNFRSF19,TRIM46,BCAN,FAM214B,SLC11A1,RCOR3,BDP1,ATP10B,NKAIN2,CUX2,THRA,ENHO,ZFP91,TMOD1,FAM124A,TNR,TSN,TSC1,RPL7L1,CCDC136,SLC26A10" MicroRNA hsa-miR-4316:mirSVR_highEffct hsa-miR-4316:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.40E-35 3.59E-31 1.67E-34 1.53E-33 96 432 "KIAA1324,TAOK1,LRCH2,LGR5,ARHGDIA,ATM,BACH1,GYG2,CBR1,RAB28,GDA,SNCAIP,MICAL2,NRSN1,BOC,EARS2,TM9SF4,RABGAP1L,SLC29A4,DYRK1A,E2F5,E2F6,TMEM35A,GPHN,PIPOX,EYA1,MRVI1,GTF2IRD2,NOP56,EFCAB2,SORBS1,KHDRBS3,DKK3,ERAP1,PPARGC1A,PRUNE2,PCLO,GRIK3,KAT7,ATOH8,IRF8,GAREM2,RBPJ,LIX1,KCNJ10,FGFBP3,SMAD9,MAOB,MBD1,MBNL1,ZNF862,NELL1,DNHD1,PCBP3,NTRK3,PFKFB2,CAMKV,ZNF655,PLP1,MBOAT7,FSD1,DKFZp779M0652,STK32A,EML5,ZSCAN2,TUG1,FIGN,CCDC82,SETD5,CARF,ZNF568,FAM192A,ATXN2,FNDC3A,EFHD1,MAPKBP1,SNRPN,SON,CAND2,KDM4C,NPAS3,SSTR2,MTCL1,ANO4,HIF3A,CYB561A3,PMS2CL,TIE1,C5orf64,DCBLD1,RICTOR,ZNF45,PLPP4,LRP8,EPM2A,CAMK1G" MicroRNA hsa-miR-1288:mirSVR_highEffct hsa-miR-1288:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.66E-35 3.74E-31 1.73E-34 1.60E-33 85 342 "NDRG3,SLC12A5,PTCHD1,INTS2,KIAA1324,KCNT1,CADPS,CANX,NPIPA1,PPT2,CLCN3,TMEM59L,ARHGEF6,FAM149A,LETMD1,CREM,HAPLN1,ATRNL1,VCAN,CTNND1,NOS1AP,HEPH,ELMO1,KIF19,DTNA,KRBA2,EGFR,PLEKHA1,SIRPB1,FAM198B,CORO2B,CHST15,SLC9B2,OLFM1,FGF13,JKAMP,SORBS1,ATP2C1,MEGF11,FAM120B,LRRC37A6P,TDRKH,GRIK2,ZNF496,IL1RAPL1,GPR45,HNMT,ZNF546,ZNF678,ITGAV,LAMP2,MOBP,BEX5,NEUROD1,PDCD2,PRIMPOL,CRLS1,PROX1,VPS13C,CASTOR1,TMEM231,ARID4A,PBRM1,ATP8B4,CNTNAP3,FBXO11,PAAF1,SLC2A5,SLC8A2,NPAS3,SRPK2,TAB2,SULF2,ANKRD28,ANO4,RNF216P1,HHIP,SYNPO2,TRIM9,SLC30A3,ADAMTS9,PAK5,KAT6A,TIGD6,FXR1" MicroRNA "AAAGGGA,MIR-211:MSigDB" "AAAGGGA,MIR-211:MSigDB" MSigDB 6.69E-35 3.76E-31 1.74E-34 1.60E-33 67 211 "TTYH1,ADCY6,AP2A2,KLHL13,SPOP,ATP2B1,DCAF5,KALRN,USP6,CDC25B,CDC42,CDH2,CCPG1,SOCS6,CHN2,CREB5,GAPVD1,DNM2,DMTF1,DYRK1A,FRY,EFNB3,CELSR3,APH1A,ING4,ELAVL3,RPS6KC1,SGIP1,SLC37A3,NBEA,KHDRBS3,GABRB3,BRPF3,FREM1,PPARGC1A,GPM6A,NR3C1,GRM1,KLF12,SCRT2,STXBP5,NCOA7,MBNL1,KITLG,NOVA1,NPTX1,NTRK2,PCDH9,XRN1,PRRX1,POU3F2,SEC61A2,FBXW7,ZCCHC24,SOX11,ZNF423,SMOC1,SATB2,TCF12,SIRT1,ZFP91,RICTOR,PRDM2,ADAMTS9,SLC17A7,ST7,JPH3" MicroRNA "AAAGGGA,MIR-204:MSigDB" "AAAGGGA,MIR-204:MSigDB" MSigDB 6.69E-35 3.76E-31 1.74E-34 1.60E-33 67 211 "TTYH1,ADCY6,AP2A2,KLHL13,SPOP,ATP2B1,DCAF5,KALRN,USP6,CDC25B,CDC42,CDH2,CCPG1,SOCS6,CHN2,CREB5,GAPVD1,DNM2,DMTF1,DYRK1A,FRY,EFNB3,CELSR3,APH1A,ING4,ELAVL3,RPS6KC1,SGIP1,SLC37A3,NBEA,KHDRBS3,GABRB3,BRPF3,FREM1,PPARGC1A,GPM6A,NR3C1,GRM1,KLF12,SCRT2,STXBP5,NCOA7,MBNL1,KITLG,NOVA1,NPTX1,NTRK2,PCDH9,XRN1,PRRX1,POU3F2,SEC61A2,FBXW7,ZCCHC24,SOX11,ZNF423,SMOC1,SATB2,TCF12,SIRT1,ZFP91,RICTOR,PRDM2,ADAMTS9,SLC17A7,ST7,JPH3" MicroRNA "TTTTGAG,MIR-373:MSigDB" "TTTTGAG,MIR-373:MSigDB" MSigDB 9.30E-35 5.22E-31 2.42E-34 2.23E-33 67 212 "DSCAML1,KLHL13,ALK,PITPNM2,PKP4,TMEFF1,ARHGAP5,SLC4A4,ST3GAL5,CACNA1G,CAPN3,KRIT1,CFL2,ARMC8,IFFO1,CSNK1E,DLG4,DNAJB6,SH3GLB1,PHF20L1,MBNL2,ING4,EN2,WAC,GABRB3,ARFIP1,PPARGC1A,RNPS1,TNRC6A,GRM3,PTPN5,PSIP1,ELOVL5,JAK2,IPO5,MBP,MYCN,TRHDE,EPB41L4B,PPP2R5C,PPP3CA,MDGA2,ELOVL2,ARID4A,KHDRBS2,RIC8B,FBXW7,KCNIP2,TRA2B,PPM1E,PKNOX2,ZCCHC24,SP2,NMNAT2,LARP4,GSE1,SYT4,CLASP1,UBE3A,FLRT2,XPO1,ZIC2,PMEPA1,CSDE1,SLC17A7,GOPC,PHTF2" MicroRNA hsa-miR-6873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.49E-35 5.33E-31 2.46E-34 2.27E-33 91 392 "AS3MT,ACTN2,GRAMD1B,NLGN4X,MTA3,SORCS2,SPOP,ASCL1,PTCH2,ATP1A3,ATP2B1,PROM1,CABP7,CD86,CDH8,GPR37L1,RAB3C,CLU,RIMS4,CST3,PLXNA4,PITPNM3,GAPVD1,SMG7,RCAN1,ELAVL3,EMX2,NRN1,TUBB4A,GABRA1,GABRG2,GALC,GALR1,GATM,FAXC,PCDH17,GJB1,GPR26,PARD3B,GRID1,PTGDR2,FRMD3,LSAMP,MDM4,CD200,NFIX,DDR2,ZDHHC22,PALM,PDE3A,GDAP1L1,PLCL1,KANSL1,SNRK,SH3TC2,RDX,ZYG11B,ATXN1,ATXN7,SCN2B,ZFP30,CPEB3,CHD9,SLC6A8,ZFP1,ZNF667,IGSF9B,LIMCH1,ZNF415,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,MGRN1,TMEM151B,TGFBR3,HHIP,FBXL16,BHLHB9,TNS1,TSC1,UBE2H,ZNF23,CADM2,PRDM10,NAV2,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-370:PITA hsa-miR-370:PITA_TOP PITA 1.08E-34 6.04E-31 2.79E-34 2.57E-33 61 174 "ASIC1,XKR4,PCDH19,RTL9,TAOK1,ANK3,CNIH2,CNTNAP1,USP37,AQP4,CASK,DDX3Y,SLC4A4,B3GALT2,DCAF5,JAZF1,BSN,CANX,MAGI1,SRSF11,MAP4K4,HAPLN1,RIMS4,ARHGEF4,DOCK4,CTIF,SMG7,DRP2,PHC2,EFNB3,PSD2,NTNG2,PCDH11X,PRRC2B,CIT,ADAMTS6,ATXN2L,KLF12,KCNJ11,MBNL1,MYO6,PPP5C,VSTM2L,USP47,RAP1GDS1,STX1B,ATXN1,STUM,FAM102A,ST3GAL3,NFASC,CLASP2,NCDN,EXOC7,DICER1,DCBLD1,CCDC136,POLR3H,PRDM10,NAV3,KAT6A" MicroRNA hsa-miR-622:PITA hsa-miR-622:PITA_TOP PITA 1.18E-34 6.62E-31 3.06E-34 2.82E-33 72 247 "AMPH,API5,ATP1B3,ATP2B1,PTBP2,MAP7,LARGE1,FAM19A5,MAP4K4,APPL1,GAPVD1,IP6K1,ELMSAN1,DLG2,CPEB2,EDNRA,HEYL,ANKRD13B,EYA1,NRN1,ANKFY1,MEGF10,PCDH17,GHR,RUNDC3A,GRIN2D,NR3C1,LINGO1,AGFG1,KCNB1,KCNK2,KIF5C,STMN1,MBNL1,NFYA,CLDN11,ZNF827,PBX1,IRX1,MAPK3,PTK2,TMEM255A,SUSD4,ARID4A,KHDRBS2,RGS7,RNF220,FBXW7,LGR4,SALL1,SATB1,CSRNP3,LRFN5,FNDC3A,FHOD3,CCDC88A,SOX11,ZSWIM8,POGZ,SS18,PLCB1,CAMTA1,UNC5D,RIMBP2,PDSS1,TRPS1,CCDC14,ZBTB14,SMARCAD1,PARP6,SLC17A7,PHTF2" MicroRNA hsa-miR-1289:mirSVR_highEffct hsa-miR-1289:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-34 7.08E-31 3.27E-34 3.01E-33 100 470 "SYS1,HFM1,SPOP,AMT,LCORL,PKP4,NT5C3B,SEMA4G,MADD,ARNTL,BACH1,CFLAR,SCAPER,C5,CA12,LURAP1,CALM1,KALRN,NFS1,ARHGEF2,LGI1,CHM,RAB33A,FBXO7,MFSD4A,ATRNL1,VCAN,CST3,CFAP61,CX3CR1,TMEM170A,DAPK1,BRINP1,DNAH9,SLC25A18,ABCC5,EDN3,PHC2,FCF1,AASS,TMEM35A,KCNMB2,DUSP27,TLR7,KAT8,FER,POLK,WDR83,ILDR2,IQGAP2,DISC1,KIAA1841,PLPP7,MAN1B1,MAT2A,FXYD6,NCAM1,CCDC13,SMIM11A,TREM2,PDGFRA,PDYN,STRN3,SPATA6,PPP2R5E,CEP41,TMEM145,PLEKHB2,SLC25A41,SUSD4,NUDT11,ARMC5,CARF,ELP2,R3HDM2,ST3GAL3,ZNF365,SMARCD3,SNAP25,MBD5,SON,NMNAT2,PEG10,SYT11,FGD4,SYN2,TAC3,DOCK9,CHST5,RUNDC3B,MEIS3,SLC30A4,SLC17A7,PDSS2,DNAH10,MARCH8,FBXO36,CASC15,RSPRY1,ZNF30" MicroRNA hsa-miR-668:mirSVR_highEffct hsa-miR-668:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-34 7.12E-31 3.29E-34 3.03E-33 97 444 "KLHL32,CCDC85A,ADD1,ABCD2,FAM131A,API5,USP37,ARRB2,ASPH,DPY19L3,DST,CALB1,CALB2,CAST,SYNGR3,CDH2,ZMYM4,RCBTB2,DNAJB5,TMEM155,ARMC8,IFFO1,TRIM69,ARHGEF10,DZIP3,PHF14,BOC,DGKG,IP6K1,DDX46,DPP6,E2F6,EDNRB,EML1,EMX2,EPHB1,EFEMP1,CEP78,FGFR1,BRPF3,ERAP1,KIAA1841,SRCAP,GHR,TOX3,GNAO1,TMEM121B,ATXN2L,SYNPO,NEGR1,KCNK2,FGFBP3,GPR155,MEIS1,MT1M,MXI1,NELL1,CCDC13,CNOT4,LOC100128398,PAK3,PCDH9,NALCN,EXOSC10,PRRX1,SDK2,POU3F2,RNASEL,RAVER2,CCDC102B,CCDC112,SLA,LRRC55,ZFP1,SMARCD3,SNCA,SP4,CLUAP1,CDK19,CLASP2,NECAB1,SYNE2,ZEB1,EIF4ENIF1,VGF,TRIM9,LYPD6,ZSCAN26,SMARCAD1,EMSY,DNALI1,HPS4,NAV3,SLC17A7,SMIM8,ACTR3B,SLC4A10" MicroRNA hsa-miR-1975:mirSVR_highEffct hsa-miR-1975:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-34 7.13E-31 3.29E-34 3.03E-33 110 560 "SDE2,NDRG2,FMNL2,AK2,SPOP,UPRT,BCAS1,NUMB,ATP1A1,FUBP1,C5,CACNA1E,ZNF501,CHM,DNAJB5,CNTN1,CP,TRIM69,PNPLA8,CTNND1,HDAC4,DNAJC6,C8orf34,ZEB2,HP1BP3,COPS7A,SNAP91,WDR20,NR1D2,ANKRD46,FRY,PHF20L1,ABI2,RACK1,FOXG1,ATP13A4,SGIP1,DCTN2,JKAMP,GABRB1,WASHC2A,TXNL4A,GNAO1,GRM7,TOX2,NKD1,GAREM2,RIPPLY2,INSM1,CREG2,STXBP5,MAT2A,MOBP,NCAM1,PAK3,PRTG,GPR173,GNG2,A2ML1,PLIN1,POU3F2,EPDR1,WBP1L,TMEM260,STRC,ZNF793,DPF2,RFX5,RNASEL,RPE,SPIN3,CNTNAP3,LGR4,FBXO11,NLGN1,ST3GAL3,SLC6A1,SLC8A1,CCDC88A,SLC14A1,IFT122,RIMS1,HECW1,KDM4C,TEX2,SSTR2,ELOVL4,FAM168A,VAMP1,VPS13A,PLCB1,SYN2,ZEB1,WDR7,SIRT1,TMPO,RIMBP2,PRMT8,STXBP4,TRPC3,PRR18,CADM1,CCDC136,LAT2,CFAP298,ZIC2,ZBTB16,LRP8,UBE3B,CASC15" MicroRNA hsa-miR-132*:mirSVR_lowEffct hsa-miR-132*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.29E-34 7.26E-31 3.35E-34 3.08E-33 95 427 "DPF1,ADAR,CC2D2A,SMIM17,APBA2,UPRT,CADPS,ASGR1,NUMB,ATM,SNAI3-AS1,BID,LDHD,SYNJ2,CACNA1B,P2RX6,UBE2L6,LHX2,CPNE6,NRXN3,RAB26,ENTPD4,GDA,CSNK1E,PLCH2,DCAF4,GUCD1,SGSM2,EXOG,DNM2,CPEB2,SPEG,REEP2,ZIC4,FDFT1,CAP2,NELFCD,WDR83,NSG2,DOT1L,DISC1,ATP8A2,MSTN,RND1,SPIN1,STARD3,FERMT2,GRIA2,PTPN5,MFSD2A,OPALIN,RBPJ,HES5,KIF5A,LYPLAL1,MAT2A,ADAM11,KCTD6,MYH6,VWA2,NUCB2,CDK18,PDE2A,PDGFRA,GDAP1L1,LRP12,PCDHB17P,LRRN3,WBP1L,GON4L,PIGG,RAP1GDS1,ZDHHC14,CCDC25,NEK11,PRR5L,ITSN1,FERMT1,SLC8A3,ARFGAP1,MBD5,SOX11,SSTR1,SS18,STAU1,SYP,CUX2,AKNA,RNF216P1,KCTD2,RGMB,AMACR,PPIL6,KCNE5,HPS4" MicroRNA hsa-miR-488-3p:TargetScan hsa-miR-488-3p TargetScan 1.29E-34 7.27E-31 3.35E-34 3.09E-33 80 306 "KIAA1211,HECW2,APBB2,MARCH3,ATP2B1,RIPK1,CALM1,REPS2,LGI1,RAB3C,ARHGEF6,ARHGAP24,KIAA0087,KLHL3,CHRDL1,EBF1,EPHA5,RAB9B,FGFR3,FAM49B,FUT9,SDCBP2,GABRB3,RAB30,PRRC2B,PRUNE2,RAPGEF4,GRIN2D,PTPRT,RNF165,GUCY1A2,RNFT2,CELF3,HAS2,IGF1,PLD5,DIPK1A,KCNN3,MAT2A,ADAM11,PPM1L,MMP16,SAMD5,NDUFA5,NFIA,PCSK5,PDE3A,NLGN3,PIK3R1,FTO,PCDH18,POLR2F,PKIA,FITM2,APTX,ANKHD1,PRIMA1,CYB561D1,RIMKLA,AP1AR,SARS,CCDC88A,FAM126B,HECW1,MYCBP2,PEG10,ANKRD28,ANKRD12,FAM208A,CBX5,CSMD1,HEPACAM,CADM1,AMOT,PLEKHH2,EML6,PRDM10,RGS7BP,CERS6,RSPRY1" MicroRNA hsa-miR-335:PITA hsa-miR-335:PITA_TOP PITA 1.30E-34 7.29E-31 3.36E-34 3.09E-33 63 187 "ELFN2,CCDC85A,CDC7,SORCS1,PCDH19,SLC4A4,BCL2L2,TMEM257,CHM,NRXN1,OSBPL3,FAM131B,DOCK4,LONRF1,SPOCK2,FAM107B,ABCC5,RBM12,ELAVL3,ERBB4,KDM2B,RAB40B,KAT7,ZHX1,HMGCR,ITPKB,ARHGAP12,MAP2,PCDH9,GNG2,ZDHHC8,STRN3,EPB41L4B,FAT3,NXPH1,POU3F2,PPP2R5C,MAPK10,TMEM260,ZNF532,SALL1,SCN2A,SCN2B,PPM1E,CPEB4,ZSWIM8,NMNAT2,KDM4C,ZC4H2,SYN2,CAMTA1,TCF4,PSD3,TIAM1,RBFOX2,TSC1,RPRM,UBE2H,POLR3H,EVI5,RGS7BP,GOPC,HNRNPA3" MicroRNA hsa-miR-4668-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-34 7.64E-31 3.52E-34 3.24E-33 92 402 "XKR4,AXIN2,SLC24A4,ZNF608,OGT,PHF12,ZBTB10,LDHD,AP1M1,CALM1,USP2,CACNA2D2,GPR37L1,HECTD1,CNN3,RTTN,HS3ST5,HAPLN1,USP6NL,MTX3,DLG4,DPP6,ABCC9,EDIL3,GPR61,BSCL2,DLC1,FECH,FGF12,TMEM164,SALL3,WASF3,PPARGC1A,CRCP,RAB30,TNRC6A,DCLK2,GNG3,FICD,HMGB1,NEGR1,LIX1,KCNB1,STMN1,MAOB,MAT2A,MDM4,MEF2C,NFYA,IGSF11,OCRL,ZNF713,PDE4D,PDGFRA,PDPK1,PKM,EPN1,EPB41L4B,DRAM2,RASGEF1B,RAP1GDS1,ZYG11B,RFX3,SLC25A36,GSTCD,KIAA0895L,ATAT1,ZNF568,NCBP3,SOX6,SH3BP2,SP4,UHRF1BP1L,SPART,TAB2,NXT2,SLC44A1,NACC2,ZFP91,RGMB,TRPS1,TSC1,RFTN2,UBE2H,SLC30A4,PRDM2,NAV2,ITM2C,WIPF2,WNK3,VANGL2,GAN" MicroRNA hsa-miR-2861:mirSVR_highEffct hsa-miR-2861:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-34 7.64E-31 3.52E-34 3.24E-33 92 402 "CPNE2,SERPINA3,SYS1,SORCS1,CC2D2A,SHTN1,PCDHGB4,NUMB,SRSF11,STOML1,SLC25A27,COL9A2,SIRPA,DDX46,HS3ST4,DPP6,EDNRA,SUGP2,COQ7,RASGRP2,RACK1,FCGRT,CAMSAP1,CAP2,PSD2,DPYSL4,ILDR2,SALL3,ALDH1L1,USP19,PPARGC1A,GRIK2,ATE1,LINC00839,COQ10A,MAEL,TCEAL6,KIAA1755,MBNL1,MYH6,MYO7A,NCF2,NME4,NOVA1,DNHD1,TBC1D25,PCDHGC3,PDGFRA,PENK,ANKRD16,EXOSC10,EPDR1,GRAMD1C,WBP1L,PTPRD,RASGRF2,PBRM1,UEVLD,ATAT1,SEC14L1,ITSN1,ZNF365,SLC1A7,SMARCD3,MYH15,SMARCE1,SON,CAND2,KDM4C,DBNDD2,ADHFE1,ABCC8,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,AKNA,TNS2,SIRT1,CDK20,AMACR,REEP1,CASC15" MicroRNA hsa-miR-1228:PITA hsa-miR-1228:PITA_TOP PITA 1.45E-34 8.13E-31 3.74E-34 3.44E-33 62 181 "SDE2,ARID1A,CCDC85A,DPP10,PKP4,DDX3Y,JAZF1,LDLRAD4,USP6,CDH10,DLGAP2,SOCS6,NRXN1,IGDCC3,CLOCK,CREB5,CRY2,SLC32A1,CSNK1G3,SMG7,SRGAP3,RBM12,TMEM35A,EN2,EYA1,FOXG1,C15orf41,ATP8A2,TCERG1,TNRC6A,IL1RAPL1,HRH3,BACH2,ZIC5,ZC3H12B,NFIA,PCSK2,MAPK10,PTPRD,ZFHX4,ATXN1,CASC3,CPEB3,CPEB4,FAM219A,MYT1L,SOX3,NPAS3,TAB2,SS18,TTBK2,RGL1,SYT1,CAMTA1,TJP1,TPM1,TSC1,CADM1,USP1,POLR3H,WIPF2,ST8SIA2" MicroRNA hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 1.50E-34 8.42E-31 3.87E-34 3.57E-33 79 299 "NDRG3,GALNT16,ADCY6,OSBPL6,OGT,DPP10,AQP4,NCOA1,CADM3,BACH1,BCL2L2,NIPA1,NOG,NUMBL,LHX2,RBM39,ERC2,HDAC4,RASSF2,MATR3,SCRN1,KIAA0753,MAGI2,GUCD1,DPYSL2,DTNA,KLHL5,EIF4G2,ELAVL2,CERCAM,EPB41L2,ERBB4,EXTL1,FECH,ANKFY1,CELF1,NCKAP1,PPARGC1A,GLUL,PSRC1,RFFL,IL1RAPL1,ARHGAP19,MIER3,KCND3,LAMP2,MARK1,MPP2,GIT1,PABPC1L2A,NFE2L2,NFYA,PAX6,PDGFRA,GPR85,MAPK4,RIC8B,PBRM1,AMER2,SBF1,HSPA4L,FAM102A,PPP1R9A,MYCBP2,KIF1B,CLSTN2,ATP11A,ANKRD12,ACSL6,SATB2,GPRIN3,GPR161,HEY1,NPL,RGMB,FNDC5,FLRT2,POLR3H,FXR1" MicroRNA hsa-miR-190:PITA hsa-miR-190:PITA_TOP PITA 1.66E-34 9.31E-31 4.28E-34 3.94E-33 58 157 "SLITRK1,ZNF608,KLHL13,TBC1D14,OSBPL6,ADGRB3,SYNJ1,LDLRAD4,SOCS6,NRXN3,CNN3,CREB5,SEC24C,BOC,MYEF2,CEP170,MAGI2,DMD,DRP2,SEMA3D,TENM1,GPHN,TAOK3,MEX3B,NBEA,PHYHIPL,MEGF10,C15orf41,TNRC6A,HAS2,BACH2,NEGR1,KCNA4,MEF2C,NEUROD1,HCN1,PCDH9,XRN1,POU3F2,PPP2R2C,DIRAS2,ROBO2,SGSM1,TRA2B,FNDC3A,NLGN1,MYCBP2,LARP4,KLHL7,ANO4,TCF4,DICER1,CSMD1,CADM1,ZIC3,CELF4,CA10,NAV3" MicroRNA hsa-miR-190b:PITA hsa-miR-190b:PITA_TOP PITA 1.66E-34 9.31E-31 4.28E-34 3.94E-33 58 157 "SLITRK1,ZNF608,KLHL13,TBC1D14,OSBPL6,ADGRB3,SYNJ1,LDLRAD4,SOCS6,NRXN3,CNN3,CREB5,SEC24C,BOC,MYEF2,CEP170,MAGI2,DMD,DRP2,SEMA3D,TENM1,GPHN,TAOK3,MEX3B,NBEA,PHYHIPL,MEGF10,C15orf41,TNRC6A,HAS2,BACH2,NEGR1,KCNA4,MEF2C,NEUROD1,HCN1,PCDH9,XRN1,POU3F2,PPP2R2C,DIRAS2,ROBO2,SGSM1,TRA2B,FNDC3A,NLGN1,MYCBP2,LARP4,KLHL7,ANO4,TCF4,DICER1,CSMD1,CADM1,ZIC3,CELF4,CA10,NAV3" MicroRNA hsa-miR-128-3p:Functional MTI Functional MTI miRTarbase 2.81E-34 1.58E-30 7.26E-34 6.68E-33 106 528 "SDE2,ACADM,ADD1,FZD9,PTCHD1,INTS2,TAOK1,GAS7,GPAM,ARHGAP5,ALDH4A1,RNF182,AZGP1,CANX,HIP1R,CCNT1,INA,KMT2C,ZNF385A,PNKD,CREB5,ABCG1,CSF1,RGS6,PHF14,PYGO1,BOC,LONRF1,LIN54,SEC16A,KBTBD11,NR1D2,EGFR,KMT5B,EIF5,EN2,EPB41L1,EPHB1,DNAJC27,ATP8A1,TOMM40L,POLR1B,SUCO,ANKFY1,NBEA,FAM49B,FYN,HRASLS5,GCNT2,RND1,TPPP,KAT7,MIER3,C2orf72,IGF1,ZIC5,SLC6A17,JAK1,KLHL23,LIFR,ARHGAP12,MKLN1,MPP2,BLOC1S2,MYO9A,NTRK3,PDE3A,PDE3B,PDPK1,PIK3R1,PKD1,PDZRN4,SDK2,RETREG2,RELN,CNNM2,VPS13C,SNRK,ZYG11B,RET,RFX3,ZFHX4,FBXW7,RXRA,CASC3,R3HDM2,CPEB4,ZFP1,WDTC1,SOX2,FNBP1,SOX11,PEG10,SPTAN1,CDK19,TROVE2,ITPRID2,MPRIP,FRYL,SIRT1,TGFBR3,ARL10,HEY2,TUB,WRN,RICTOR" MicroRNA "GTTTGTT,MIR-495:MSigDB" "GTTTGTT,MIR-495:MSigDB" MSigDB 2.88E-34 1.62E-30 7.41E-34 6.83E-33 70 236 "OGT,ARHGAP5,NCOA1,DDX3Y,ATP2B2,ADGRB3,CAMK2G,RUNX1T1,CBFA2T2,SEPT7,LARGE1,SRSF11,LHX2,CNR1,ARMC8,CSNK1E,RIMS4,ST18,NTM,DYRK1A,MBNL2,RGS17,BAIAP2,FOXO3,AFF2,CELF1,STAG2,ATP8A2,TNRC6A,GPM6A,EML4,GRM7,AGBL5,IGF1,MARK3,PDE4D,HMGCLL1,EPB41L4B,PPP3CA,PRRT2,RPRD1A,RORB,SEMA6D,SATB1,SCN8A,SOX6,SGK1,CPEB3,FAM219A,WDTC1,MYT1L,SOX5,SP4,GSE1,WASHC4,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RASD2,UBE3A,RICTOR,ZIC3,USP32P2,EMSY,ST8SIA2,CPNE4" MicroRNA hsa-miR-32-5p:Functional MTI Functional MTI miRTarbase 2.93E-34 1.65E-30 7.55E-34 6.96E-33 110 565 "SLC12A5,GRAMD1B,CASKIN1,OSBPL8,FAM135A,USP28,ATP2A2,CDK5R1,DST,SYNJ1,CDC27,CLTA,TMEM184B,HECTD1,CREB5,APPL1,EDRF1,EARS2,LIN54,SPOCK2,GIT2,DBT,SPATA2,HP1BP3,G3BP2,CPEB2,ARRDC4,MRO,KMT5B,PLEKHA1,RGS17,EIF1,DNAJC27,PRMT5,KIAA1109,SLC37A3,USP21,NPTN,GAA,HBS1L,GLYR1,KIAA1958,PRRC2B,FUT10,LILRA2,TPPP,NR3C1,ZHX1,MIER3,HMGCR,AGBL5,EID2B,C5orf24,ZIC5,RBPJ,IL6ST,ITGAV,LAMP2,PIK3AP1,SESN3,MYO5A,CNOT4,PIK3CD,CCSER2,SNX10,ZFYVE21,XRN1,PURG,TATDN3,UHRF1BP1,MTMR10,REV3L,SLC25A36,SETD5,RPE65,FBXW7,ATXN1,FNIP1,CPEB3,SYBU,ZNF430,ATF7IP,CPEB4,FAM126B,SOX11,TEX2,KIF1B,MCF2L2,PBLD,ITPRID2,ERBIN,TACC1,AGTPBP1,DOCK9,RBFOX2,TRIO,TSC1,SGK3,ZNF17,ZNF24,PMEPA1,ZXDA,MFF,EVI5,XKR7,RNF103,PHTF2,NHSL1,FXR1,GAN" MicroRNA hsa-miR-508-5p:PITA hsa-miR-508-5p:PITA_TOP PITA 3.22E-34 1.81E-30 8.30E-34 7.65E-33 64 196 "SDE2,BCL7A,KSR1,SYNJ1,BSN,SYT6,FOXN3,RAB33A,SLC35F1,CREB5,AKAP12,OSBPL3,CTNND1,HDAC4,SV2A,TMCC2,DLG2,DMD,EGR3,CELF1,FUT9,GLS,TNRC6A,MAP4K5,IGF1,INSM1,KCND1,KIT,ARHGAP12,KITLG,MYO6,NEXMIF,NCAM1,NEFH,SLC11A2,NTRK2,PCSK1,PDE4B,MINDY2,PTK2,TMEM260,SH3TC2,FIGN,RGS7,FBXW7,RTN1,ATXN1,CPEB3,SOX11,TTBK2,FAM168A,VAMP1,ANKRD28,ATP11A,TBL1X,TCF4,SATB2,NSD1,FRYL,RELL2,DOK6,AMOT,ZIC3,ZNF189" MicroRNA hsa-miR-6825-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.81E-34 2.14E-30 9.80E-34 9.03E-33 89 382 "CPNE2,GPRIN1,RNF157,ADD2,AP1B1,CASKIN1,SORCS2,LTBP4,ANK1,PRX,ARRB1,CAMK2A,CANX,CBS,METTL6,EVI5L,JAM2,DLGAP3,CRMP1,CRY2,RGS6,SLITRK5,NOS1AP,PHYHIP,PLEKHM1,ABCC5,EFNA3,EIF4G1,ING4,EPB41L1,ANKRD13B,WAC,CELF1,BRSK1,HBS1L,NKX6-2,SRCAP,PRRC2B,SHISA6,SOWAHA,KCND1,KCNH2,KCNK3,MSI1,NBL1,NDUFA5,NEUROD2,NFIX,SLC11A2,NRGN,OGG1,PDE4A,GPR173,EPN1,SPATA6,PACSIN1,PPP2R2B,PTPA,KANSL1,BDNF-AS,PRRT2,C12orf49,RPS6KA2,EMID1,CLSTN1,SMTN,PKNOX2,FNBP1,LHFPL4,RAP1GAP2,NFASC,CLSTN2,CAMTA2,SSTR1,MAPK8IP3,FAM168A,USP22,SLC19A3,THRA,NACC2,CBX5,KCTD2,UBTF,MGAT5B,KLC2,RICTOR,URM1,NAV2,HNRNPA3" MicroRNA hsa-miR-342-3p:TargetScan hsa-miR-342-3p TargetScan 3.81E-34 2.14E-30 9.80E-34 9.03E-33 69 230 "PPFIA4,APBB2,BSN,CA12,P2RX6,CFL2,RAB3C,PLAA,SEC31B,CSF1,DNAJC6,DNM1,DSCAM,EDNRA,ABI2,FLNC,NBEA,CAMKK2,CELF1,NCKAP1,GFRA1,PCDH17,GPR75,GRIN1,GRIN2D,BTN2A1,KAT7,FAM222A,FRMD3,AGFG1,METTL21A,KCNA4,IPO5,NCOA7,LSAMP,MDM4,AFF1,MSI1,NKX2-2,OPHN1,PDE3B,PDGFRA,CAMKV,NOMO2,PPP2R5E,CNNM2,PTPRN2,FIGN,RFX3,RGS4,PRIMA1,RPRD1A,HUNK,FAM192A,EPN2,BTBD7,EPC1,FAM126B,COLGALT2,LRRC4,MLC1,MMS19,FAM208A,PDLIM2,CUX2,NSD1,CBX5,PLEKHH2,LRP8" MicroRNA hsa-miR-548b-3p:PITA hsa-miR-548b-3p:PITA_TOP PITA 3.81E-34 2.14E-30 9.80E-34 9.03E-33 69 230 "PLEKHG5,SLITRK1,SLC12A5,PCDH19,OSBPL8,SEMA6A,CACHD1,CPNE5,BRINP2,BCL7A,JAZF1,MAP7,LDB2,CERS5,DLGAP2,SOCS6,CLCN4,CREB5,RIMS4,MATR3,CPEB2,GOLT1B,CNNM1,KMT5B,PAN3,STX2,ZIC4,DLC1,FGF13,DCTN2,NBEA,STAU2,NCKAP1,PPARGC1A,RNF165,ADAMTS6,HMGB1,ZIC5,LRRTM3,GPR155,LRP1B,NEUROD2,IGSF11,POLG,MED1,FAM120C,RAB5B,TMEM255A,RFX5,NUDT11,SALL1,LRRTM4,SMPD3,MAGI3,EPN2,RCOR3,RBM26,NPAS3,LARP4,NSFL1C,PLCB1,PUM2,DICER1,NR2E1,TPD52,AMOT,USP1,TOM1L2,SMARCAD1" MicroRNA hsa-miR-376c-3p:TargetScan hsa-miR-376c-3p TargetScan 4.54E-34 2.55E-30 1.17E-33 1.08E-32 64 197 "GRAMD1B,KCTD16,ALCAM,CNIH2,PDE8B,NCOA1,DOCK11,CACNA1G,LDLRAD4,CACNB2,CALB1,PTBP2,CBLN1,LRWD1,NRXN3,PYGO1,RIMS3,ELMSAN1,MFAP3L,EDN1,FRY,EN2,ANKFY1,FAM49B,GABRG2,PCLO,RFFL,GRM5,FRMD3,HNRNPK,NKD1,LSAMP,MEIS2,MMP16,ADAM22,HCN1,OPCML,PROX1,PTPRB,PTPRD,ARID4A,GAL3ST4,RAVER2,ROBO1,RORB,AMER2,SATB1,FAM19A1,CPEB3,NTNG1,ABLIM3,CPEB4,IGSF9B,LIMCH1,RAP1GAP2,LARP4,C3orf70,HHIP,DOK6,RFTN2,RGS7BP,KAT6A,NETO2,NETO1" MicroRNA hsa-miR-24-3p:Functional MTI Functional MTI miRTarbase 4.83E-34 2.71E-30 1.24E-33 1.14E-32 139 855 "XKR4,ADD1,ADD3,PLEKHH1,ESYT2,TBC1D14,TXNDC16,TAOK1,TRMT9B,AMPD2,APAF1,PDXK,CCAR2,EIF4G3,STX16,BCL2L2,BCL7A,BMP7,ARHGEF7,NAE1,GYG2,NIPA1,REPS2,LONRF2,ZBED1,MAGI1,ZFYVE9,AKAP7,AKAP5,TBPL1,CRY2,NCAN,APPL1,GREB1,DCAF4,MATR3,YTHDC1,COPS7A,MED24,GUCD1,SLC29A4,HEYL,MRO,EIF5,TNK2,EPB41,IGSF6,SCML2,POLR1B,FGF11,FGFR3,AMOTL2,PCYOX1,NOP56,CINP,PDLIM5,MSANTD4,GABRB3,TRAF3IP2,NEK6,SESN1,BRD8,CRCP,DBF4,GLYR1,GLUL,POLL,GRK4,KIF3A,BVES,IRAK3,ARHGAP19,NEGR1,AGFG1,HSF2,IGF1,NKD1,KCNJ5,KLHL23,KCNK2,LIMS1,MDM4,SAMD5,MT1M,MXI1,NASP,ZC3H12B,SLC11A2,OLR1,PDPK1,STRN3,MAPK7,APTX,PTAFR,PEX2,HKR1,TTLL7,SETD5,C12orf49,ELP2,FBXW7,DRAXIN,ZFP30,AMBRA1,R3HDM2,NUBPL,CLSTN1,SLC1A2,BTBD3,ZNF430,SEPHS1,ZKSCAN3,INAVA,UHRF1BP1L,BEX1,DDN,ZNF621,POGZ,SS18,ZSCAN29,MMS19,DDHD2,ALG1,SLC19A3,ZNF106,RFTN2,UBC,RPL7L1,UBE3A,ZNF708,ZNF17,ZNF70,ZBTB16,ZXDA,URM1,LINC00632,FBXO36,ZDHHC20,NETO2" MicroRNA hsa-miR-223:PITA hsa-miR-223:PITA_TOP PITA 5.17E-34 2.90E-30 1.33E-33 1.22E-32 69 231 "ARID1A,DSCAML1,PKP4,APC,CAPRIN2,ZBTB10,NCOA1,ATP2B1,MTMR2,BTRC,PTBP2,QKI,SLC35F1,SLITRK5,CTNND1,TOX,PHF19,ELMSAN1,KLHL3,SACS,SRGAP3,MBNL2,F3,OLFM1,FOXO3,CSPG5,GABRB3,BRPF3,SPIN1,GRIA4,HLF,HAPLN2,RBPJ,IL6ST,INPP5B,LMO2,MEF2C,NDP,NEFH,NFIA,OPCML,PCMT1,PDE4D,ANKRD16,LRP12,RANBP3L,PKN2,WBP1L,FAM120C,TMEM255A,FBXW7,ATXN2,SCN2A,SCN3A,SCAF8,CLSTN1,SLC8A1,SOX11,ERC1,NFASC,EPB41L3,SYT1,CAMTA1,TCF4,DOCK9,HEY2,REEP1,FAM13C,PAK5" MicroRNA hsa-miR-7:PITA hsa-miR-7:PITA_TOP PITA 5.17E-34 2.90E-30 1.33E-33 1.22E-32 69 231 "CSMD3,ELFN2,OGT,PPFIA3,CDC14B,SLC4A4,ATP2B2,DIRAS1,SYT6,MAGI1,FOXN3,CNOT8,CNN3,CRY2,CLIP3,NRSN1,FAM131B,BOC,SPATA2,G3BP2,DPYSL2,ABI2,EGR3,ERBB4,ACSL4,PTK2B,FGF13,CAMSAP1,GAD1,GLS,ADAM11,HCN1,CHAMP1,OPCML,PDE4B,PDE4D,CCSER2,ST8SIA5,PLEC,MAPKAP1,STRN3,PRKCB,MAPK4,PTK2,RAB5B,OXR1,ARID4A,SEMA6D,SATB1,ATXN1,SCN2B,R3HDM2,WDR47,SNCA,FAM126B,TAB2,CLASP2,NECAB1,ZC3H4,ANKRD28,ANKRD12,TCF4,TCF12,SZT2,FLRT2,FMN2,ZBTB38,WIPF2,RGS7BP" MicroRNA hsa-miR-542-3p:PITA hsa-miR-542-3p:PITA_TOP PITA 5.35E-34 3.00E-30 1.37E-33 1.26E-32 63 191 "SYS1,GPRIN1,SLC12A5,OSBPL8,ALCAM,ARHGAP5,SLC4A4,LDLRAD4,CALM1,SPAG9,QKI,HECTD1,TBPL1,CREB5,CLIP3,DBT,MAGI2,SMG7,CNNM1,ELAVL2,EPB41L1,ZIC4,SPSB4,AFF2,ZCCHC17,PHYHIPL,PCDH17,PTPRT,KLF12,ZIC5,TUBB2B,KCNA1,INSYN2,NOVA1,CDK14,SERPINE2,NOMO2,ANLN,PIK3R1,CDIP1,STRN3,REV3L,ATXN1,SCN2A,SCN3A,FNDC3A,FHOD3,R3HDM2,SLC12A2,SORCS3,SOX11,ANKRD28,CUX2,TCF12,DOCK9,PSD3,PUM2,CSMD1,TPM1,PCDH20,ZIC1,EMSY,LMAN2L" MicroRNA hsa-miR-614:mirSVR_lowEffct hsa-miR-614:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.79E-34 3.25E-30 1.48E-33 1.37E-32 92 409 "PTCHD1,BIN1,ARRB2,BCL2L2,CASTOR3,INA,MYOM2,LRRFIP1,SRSF11,HAPLN1,ANKRD44,MICAL2,SOCS5,CNTNAP2,KIAA0513,MAML1,SCRN1,ZEB2,COPS7A,DMTF1,EDNRB,PHF20L1,ABI2,IRAK4,C3orf18,EML1,FER,EFCAB2,CELF1,AP4B1,SDCBP2,GABRA1,FAM184B,ALDH1L1,GFER,PCDH11X,ADGRA3,EML4,GRIA2,CLASRP,MAEL,MAN1B1,OPALIN,METTL21A,KTN1,INSYN2,ZFYVE27,SYT9,MEIS2,MITF,XRRA1,PRTG,PDPK1,GPSM2,FXYD1,PDZRN4,PMP22,CNNM2,PTAFR,MTMR10,RALGDS,RASGRF2,RIC8B,PNMA8A,PCMTD2,DRAXIN,ST3GAL3,DZIP1,PEX26,BTBD3,ANKRD36,SNRPN,MYO16,FNBP1,CLUAP1,SYN2,FAM208A,CNTN2,FBXW11,FAM189A1,OBSL1,DICER1-AS1,TLL2,KCTD2,TPD52,ZMYND8,ZKSCAN5,ZBTB14,REEP1,ZFAND5,NUP214,IFT88" MicroRNA hsa-miR-505-3p.2:TargetScan hsa-miR-505-3p.2 TargetScan 5.84E-34 3.28E-30 1.50E-33 1.38E-32 74 267 "ADORA3,GAS7,ARNTL,ATP2B2,CAMK2D,CCNT1,C1orf52,CDC27,CDC42,CLCN3,FAM19A5,NIPBL,IGLON5,ARMC8,GDA,APPL1,CCDC144A,KIAA0408,MRO,PLXNC1,ELAVL2,OLIG2,ENPP6,PIPOX,DNAJC27,NPTN,NSG2,CELF1,NRG3,ARPP21,NCKAP1,CPLX1,GCNT2,ARFIP1,CYP46A1,GHR,RNPS1,GPR75,GNAL,PTPN5,ATOH8,RASSF8,AGFG1,KCNN3,IPO5,CAMK2N2,MBNL1,KITLG,MXI1,PDE4D,PDPK1,NLE1,PLCL1,MAGEL2,PPP2R2C,OCIAD1,GTDC1,FIGN,ROBO1,FAM192A,SALL1,BTBD3,EPN2,FAM126B,ARHGAP26,POGZ,MPRIP,GSE1,ANKRD12,ERCC6L2,CLIP2,LYPD6,FZD3,CPNE4" MicroRNA hsa-miR-374a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.25E-34 3.51E-30 1.60E-33 1.48E-32 76 282 "ABCF1,XKR4,ADD2,ADD3,USP31,GPR158,FAM135A,ATM,STX16,NRP2,ST3GAL5,CA8,SOCS6,ABCG2,HECTD1,SLC25A27,RIPOR2,DBT,PITPNC1,TMTC1,MBNL2,ACSL4,DLC1,POLR1B,SEC23B,ANKFY1,ZBED3,GABRG2,TNRC6A,LUZP2,NR3C1,WIF1,BACH2,MIER3,GABARAPL2,KLRC3,L1CAM,SESN3,CCDC80,MYBPC1,NF1,NFE2L2,OCRL,PDE4B,FAT3,EPDR1,MAPK7,RAB5B,RALGDS,SETD5,RPL38,ATXN1,BTBD3,BTBD7,CPEB4,RBM26,PBLD,STAU1,SYP,TACC1,ANKRD12,CAMSAP2,TRIM2,NSD1,SIK3,DICER1,HHIP,ZNF384,NR2C2,TRPS1,UBE3A,ZFP37,PMEPA1,LRP8,SLC38A1,JMJD1C" MicroRNA hsa-miR-181a-5p:Functional MTI Functional MTI miRTarbase 8.72E-34 4.90E-30 2.23E-33 2.06E-32 108 553 "SLC25A25,TMEM132B,KLRC4,MTUS1,HECW2,HFM1,USP28,MADD,ARRB2,PLA2G4C,CAPRIN2,ATM,ATP2B1,NOL4,MTMR3,AP1M1,ZNF445,NMT2,ABCG2,MAP4K4,PNKD,AKAP12,OSBPL3,SIPA1L1,PUM1,DCAF4,LONRF1,ELMSAN1,ZEB2,G3BP2,MTX3,E2F5,FSD1L,FAM13A,KCTD3,EN2,LRRC17,EPHA5,STX2,EPS8,ATP8A1,IQCG,SLC37A3,STAG2,CHL1,PRRC2B,WIF1,ZDHHC15,IPO5,ARHGAP12,NCOA7,BLOC1S2,FXYD6,PDGFRA,PFKFB2,ZNF426,LRRN3,PPP2R5E,PPP3CA,PROX1,C1orf109,PTPRZ1,ZNF844,PBRM1,MEG3,FAM192A,ATXN7,SCN8A,PPP1R9A,CHD9,FBXO11,BTBD3,CPEB4,ZNF667,ZNF415,TMCC1,SOX5,CLUAP1,UNC5B,SRPK2,TAB2,GANAB,PRRC2C,MTCL1,TCF4,TRIM2,PCDHB6,PCDHAC2,PCDHA7,GPRIN3,PCDHA6,PCDHA5,PCDHA3,SLC35G2,PCDHA2,PCDHA1,SIRT1,TGFBR3,HEY2,KCTD2,TUBB2A,UCHL1,PITPNB,ZNF781,NSD2,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-6797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-33 6.68E-30 3.04E-33 2.80E-32 75 277 "DPF1,ELFN2,ADCY5,RNF157,ADD2,CASKIN1,SORCS2,PHF12,PPFIA3,TTLL9,HAP1,CANX,TMEM184B,BTF3L4,NCOR2,KIAA0513,IP6K1,SPATA2,SEC16A,CHRDL1,SYT15,EPB41L1,DMTN,MTSS1L,RTN3,WAC,FGFR1,DOT1L,HBS1L,SRCAP,GLYR1,STARD3,ZBTB49,ZNF491,SHISA6,SOWAHA,NKD1,STMN1,SESN3,NBL1,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,CDK14,PKM,KCTD15,TNPO2,POLR2F,PPARA,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,PEX26,TRIM67,CAMTA2,STX1A,ASTN2,GPRIN3,HHIP,NACC2,ZFP91,KCTD2,WBP2,TUBB2A,MGAT5B,CLDND1,ZNF70,INTS3,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-1273:mirSVR_lowEffct hsa-miR-1273:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.40E-33 7.85E-30 3.58E-33 3.30E-32 100 483 "CPNE2,AXIN2,PTCHD1,OLMALINC,AP2A2,LTBP4,ARHGDIA,MARK4,ALDH4A1,TTLL9,HAP1,TRIM41,HIP1R,PRC1,EVI5L,RCBTB2,ASIC3,CHM,TPP1,HECTD1,TBPL1,PNKD,MROH8,PPP1R16B,UBXN2A,KIAA0408,HDAC4,IP6K1,PLEKHM1,CEP170,GUCD1,MAMLD1,DYRK1A,ST8SIA3,SEMA3D,ELAVL4,COQ7,ANKMY1,ABCA8,GTF2IRD2,FLYWCH1,TMEM107,CAMKK2,ERGIC3,ABLIM2,GABRB1,GGT5,CRCP,COPS8,STARD3,GRIN2C,FAM107A,MUM1,TJAP1,INPP5B,LRRTM3,C2CD4C,TTYH2,INSYN2,NAT8L,ZNF862,ZC3H12B,NFIA,DNHD1,SLC11A2,SMIM11A,CHAMP1,OPCML,PAX6,GPSM2,PLXNB1,SCHIP1,EPB41L4B,PPM1B,PRKCG,NCR3LG1,MSANTD2,RNASEL,NEK11,ATXN7,LINC00461,SLC30A10,MRAS,FNDC3A,TMCC1,FAM126B,SS18,GANAB,TMEM150C,MTCL1,TBCEL,TPCN2,AZIN2,ARL10,SEZ6L,UBTF,LAT2,ATP6V0E2,ANKS1B,LINC02210" MicroRNA hsa-miR-127-3p:mirSVR_lowEffct hsa-miR-127-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-33 8.14E-30 3.71E-33 3.41E-32 88 380 "DGCR6,DPY19L2P4,AP2A2,SHTN1,ATP2B1,RIPK1,SYNJ2,PTBP2,P2RX6,MYOM2,CDH2,L3MBTL4,MAGI1,DIS3L,ASIC3,KMT2C,CSF3R,DCAF4,BOC,DOCK4,GIT2,TIAM2,SV2A,NTM,SGSM2,ARNT2,FCF1,TLR7,TBC1D16,KAT8,BAIAP2,DACH2,TUBGCP4,COPS8,GLS,PCDH11X,GPD2,GRIA1,GRIA2,SERP2,ARHGAP36,HMGCL,USP54,KCNQ2,PTOV1,NAP1L1,NF1,NRGN,P2RX7,DPY19L2P2,MAPKAP1,SDK2,CEP41,RAB39A,MAPK8,PTPRD,TMEM145,CCDC40,RAD52,FAM66C,RGS12,ZFHX4,LRRTM4,SMPD3,ITSN1,SLITRK3,ZNF667,NPAS3,CLASP2,TACC1,CAMTA1,NAT16,RALYL,FAM189A1,AP4E1,TIAM1,TMOD1,TMPO,RASD2,OSBP2,NPDC1,GUSBP1,MICU3,SLC26A10,ZBTB38,MEIS3,DNALI1,CERS6" MicroRNA hsa-miR-657:PITA hsa-miR-657:PITA_TOP PITA 1.59E-33 8.93E-30 4.07E-33 3.75E-32 60 175 "ASIC2,USP31,INTS2,KIAA1324,OSBPL8,CNTNAP1,CDC14B,SLC4A4,KIF1A,MAGI1,CCPG1,FOXN3,NRXN1,QKI,TBPL1,ERC2,TOX,SRGAP3,CALN1,RTN3,TAOK3,NBEA,GABRG2,ARFIP1,AHDC1,DCLK2,KAT7,BACH2,MAP4,MAPT,MEF2C,PABPC1L2A,NAP1L1,ZC3H12B,HCN1,ZNF827,TNPO2,MED1,PID1,FIGN,CSRNP3,ATXN1,SCN3A,GALNT10,ITSN1,CCDC92,SEPHS1,MYT1L,ZNF423,MAPK8IP3,CAMTA1,KCTD2,TRPS1,VSNL1,ZIC1,EMSY,PPP1R3F,SNX27,KCNAB1,WIPF2" MicroRNA hsa-miR-6731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-33 9.17E-30 4.17E-33 3.84E-32 85 356 "DPF1,CPNE2,ELFN2,HACE1,TAOK1,PDZD4,KIF6,PPFIA4,PPFIA3,CDC14B,SFMBT2,SEMA4G,ASPH,DDX3Y,ADGRB2,HAP1,FMNL3,ARHGEF2,CHRNB2,EPS15L1,CLU,ARHGEF6,SUMF2,BTF3L4,RGS6,MICAL2,KIAA0513,TM9SF4,PHYHIP,SGSM2,CHRDL1,ABCC5,MRO,ING4,ELAVL3,MTSS1L,FGFR1,AMOTL2,AFF2,NCKAP1,GLYR1,GLUL,RAPGEF1,MIER3,SHISA6,IDH3A,SLC6A17,KCNK3,MDFI,PPM1L,SAMD14,PABPC1L2A,ZC3H12B,GPR137C,PDE4A,KCTD15,FTO,SDK2,PACSIN1,PPARA,SLC22A23,PTPRE,NKAIN1,MORC4,RNH1,SETD5,MYH14,SOX6,CCDC88A,ATF7IP,WDTC1,SP2,ERC1,IQSEC2,ZSCAN29,AJAP1,FAM168A,ARC,ASTN2,HHIP,TMPRSS5,TUBB2A,ZNF70,SIGLEC10,ACTR3B" MicroRNA hsa-miR-188-3p:PITA hsa-miR-188-3p:PITA_TOP PITA 1.70E-33 9.55E-30 4.34E-33 4.00E-32 68 228 "ALCAM,CNTNAP1,APP,CHRD,ZNF583,NOL4,THSD7A,PTBP2,CAMK2G,CANX,ZMYM4,LGI1,SLIT2,NRXN2,CLTC,NIPBL,COL4A5,TENM4,KCTD8,C2CD2L,SRGAP3,G3BP2,ABI1,PHC2,NRN1,CLVS1,WAC,SUCO,STAG2,GAB1,GABRA4,GAP43,PCDH17,GLDC,TNRC6A,PCDH11X,GRIA4,KLF12,ZNF181,KCNA1,INSYN2,PPM1L,NEXMIF,ZC3H12B,ZDHHC8,CAMKV,STRN3,IRX1,MED1,MAPK4,PSD,PTPRD,LGR4,NCBP3,ATXN1,RCOR3,ASTN2,ANKRD12,RPGRIP1L,ZNF384,SSBP2,FAM155A,ZNF781,ZNF711,WIPF2,MSRB3,PIANP,ST8SIA2" MicroRNA hsa-miR-216b-5p:TargetScan hsa-miR-216b-5p TargetScan 1.90E-33 1.07E-29 4.84E-33 4.46E-32 73 264 "CLK4,CSMD3,BRAP,PTCHD1,HACE1,PKP4,CASK,RUNX1T1,DGKI,DCLK1,CLGN,CFL2,DNAJB5,NIPBL,NSL1,CRY2,ABCG1,LRIG1,DZIP3,FAM131B,GUCD1,CPEB2,PDCD6IP,EBF1,ABI2,ELAVL3,ENPP6,FGF12,FGFR1,ANKFY1,GABRB1,GAD1,GLRB,GRM5,BTN2A1,FRMD5,KLF12,HLF,HMGB1,HNF4G,NEGR1,CLVS2,KCNJ5,LSAMP,MDM4,SAMD5,HS6ST3,NFIA,NFYA,PAK3,PAX6,SDK2,PRKAB2,IQSEC3,RFX3,RFX4,RXRA,HSPA4L,SCAF8,PPP1R9A,NTNG1,FNDC3A,CPEB4,CXXC4,MBD5,CMTR2,FAM126B,KIF1B,CUX2,C18orf54,HHIP,DDHD1,LRP8" MicroRNA hsa-miR-130a-3p:Functional MTI Functional MTI miRTarbase 1.91E-33 1.08E-29 4.88E-33 4.50E-32 90 398 "ADARB2,TAOK1,ABCD2,PHF12,APP,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,CSF1,DAPK1,CEP170,SEC16A,DNM2,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,SALL3,PPARGC1A,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PDGFRA,PURG,PPARA,PIGG,PXK,PTPRG,RAB5B,PTGR2,CLIP1,ATXN1,BTBD3,ATF7IP,KIF13A,SOX5,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,TAC1,CAMSAP2,ATMIN,SATB2,TCF7L2,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,SLAIN1,ZNF711,ZNF24,ZNF154,MAP3K12,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-1825:PITA hsa-miR-1825:PITA_TOP PITA 2.04E-33 1.15E-29 5.21E-33 4.80E-32 61 182 "PCDH19,CNIH2,MARCH3,MTMR9,ADGRB1,BCL7A,BSN,CACNB2,CDH2,CFL2,CLCN3,CNR1,ARMC8,SLC35F1,PHC2,KLHL5,GPR61,EML1,PAN3,REEP2,HPCAL4,FUT9,WASHC2A,PCDH17,SPIN1,PCLO,KLF12,HLF,C5orf24,KIT,CHIC1,MITF,NUMA1,PDE1C,PDYN,GPR85,CDK14,ANKRD16,PPP2R5E,PKN2,RIPOR1,FIGN,SCN8A,FNDC3A,FAM214B,CPEB4,SP2,SS18,KLHL7,PLCB1,ANKRD12,FBXW11,TCF4,HHIP,TIAM1,UBTF,SF1,TMEM237,STMN4,RTN4,JPH3" MicroRNA hsa-miR-892b:PITA hsa-miR-892b:PITA_TOP PITA 2.24E-33 1.26E-29 5.71E-33 5.26E-32 67 222 "USP31,SPOP,UNC79,DPP10,APP,ASCL1,DDX3Y,LDLRAD4,CACNA1E,CAMK2G,FOXN3,SOCS6,CNN3,SEC24C,ERC2,LONRF1,KLHL3,RAB39B,DPYSL2,MAMLD1,APH1A,ELAVL4,AFF2,CELF1,B4GALNT1,SRRM4,PCDH17,PPARGC1A,PCLO,PTPRT,MAP4K5,ZHX1,ARHGAP19,HMGCR,SMAP1,KIAA1755,KIF5C,SYT9,GIT1,NNAT,SLC11A2,OMG,MED1,MAPK3,WBP1L,RAP1GDS1,ROBO1,TRA2B,NTNG1,PALLD,CDK19,CLASP2,SS18,SYT1,WASHC4,NSD1,FBXL16,TJP1,KCTD2,RBFOX2,TUB,PITPNB,MICU3,CA10,CADM2,MSRB3,RNF146" MicroRNA hsa-miR-133a:PITA hsa-miR-133a:PITA_TOP PITA 2.26E-33 1.27E-29 5.76E-33 5.31E-32 70 243 "SNX30,LRRC7,PITPNM2,PPFIA3,ARHGDIA,CDK13,BCL2L2,JAZF1,NIPA1,CALM1,PTBP2,USP6,DLGAP3,CLTA,QKI,TBPL1,ZNF385A,CREB5,CSNK1G3,RIMS4,MAML1,ZC3H11A,DLG2,PAN3,MED12L,FGF1,DOT1L,SESN1,TTBK1,GPM6A,TMEM121B,RFFL,GRM5,FRMD5,RBPJ,KCNA1,SFXN5,ARHGAP12,MEIS1,MEIS2,NKX2-2,NTRK3,HMGCLL1,TRHDE,CDIP1,SNRK,PTPRD,PTPRO,PTPRZ1,SCN2B,CASC3,SGK1,SH3GL2,NTNG1,ST3GAL3,BTBD3,SLC6A1,SLC8A2,RIMS1,SYT1,ANKRD28,ANKRD12,FBXW11,TCF7,PHF24,PITPNB,ZIC3,CELF4,SCG2,WIPF2" MicroRNA hsa-miR-133b:PITA hsa-miR-133b:PITA_TOP PITA 2.26E-33 1.27E-29 5.76E-33 5.31E-32 70 243 "SNX30,LRRC7,PITPNM2,PPFIA3,ARHGDIA,CDK13,BCL2L2,JAZF1,NIPA1,CALM1,PTBP2,USP6,DLGAP3,CLTA,QKI,TBPL1,ZNF385A,CREB5,CSNK1G3,RIMS4,MAML1,ZC3H11A,DLG2,PAN3,MED12L,FGF1,DOT1L,SESN1,TTBK1,GPM6A,TMEM121B,RFFL,GRM5,FRMD5,RBPJ,KCNA1,SFXN5,ARHGAP12,MEIS1,MEIS2,NKX2-2,NTRK3,HMGCLL1,TRHDE,CDIP1,SNRK,PTPRD,PTPRO,PTPRZ1,SCN2B,CASC3,SGK1,SH3GL2,NTNG1,ST3GAL3,BTBD3,SLC6A1,SLC8A2,RIMS1,SYT1,ANKRD28,ANKRD12,FBXW11,TCF7,PHF24,PITPNB,ZIC3,CELF4,SCG2,WIPF2" MicroRNA hsa-miR-1914*:mirSVR_highEffct hsa-miR-1914*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-33 1.33E-29 6.04E-33 5.56E-32 99 477 "SYS1,ADD1,ADD2,PTCHD1,BEND6,RTL9,ANK2,APLP1,BCAS1,APP,RASL11B,TMEM108,SNAI3-AS1,CBS,SRSF11,LHX2,NRXN3,CNTFR,RCHY1,CLIP3,CSF1,MICAL2,UBXN2A,GAPVD1,SNAP91,DMD,ELAVL2,LRRC17,CDHR1,CLVS1,CACNG3,FCGR1A,FCGRT,STRADA,ABLIM2,GABRA3,B4GALNT1,JPH4,NEU3,PCDH17,MSL3,POLL,GPM6A,GRIA4,GRM1,TMEM25,MSL1,KCNQ3,MEIS1,AFDN,CCDC80,MYO9A,NNAT,NOVA1,LRIT2,SNTG1,CNTN3,CYTL1,EPDR1,GDPD2,PSMD13,RIPOR1,RAB5B,MSANTD2,RDX,UBR7,KLHDC8A,YY1AP1,BAALC,KCNIP3,IL17RB,GALNT10,ZNF365,LRRC55,CCDC88A,SLC20A2,KIF13A,SNRPN,SOX5,BDP1,ATP10B,ZC4H2,SEPT8,CEP68,FAM168A,FAM208A,TBCEL,RPGRIP1L,PUM2,TNS2,ICAM5,STXBP4,CADM1,VGF,WNK1,SLC17A7,TMEM163,CASC15,JMJD1C" MicroRNA hsa-miR-7-5p:Functional MTI Functional MTI miRTarbase 2.45E-33 1.38E-29 6.25E-33 5.75E-32 110 578 "CPNE2,SDE2,ACTN2,PLEKHH1,USP31,OSBPL8,ATP1B3,CFLAR,LDHD,ST3GAL5,AP1M1,ZNF555,HAP1,CAMK2D,CANX,CBS,ENTPD6,CDC25B,PLEKHB1,CNOT8,TPP1,CNN3,ZNF385A,CNTNAP2,MATR3,PITPNC1,SPATA2,SNX29,PHC2,CACNG7,EGFR,C8orf37,MFSD10,ENPP6,MRPL10,DNAJC27,FGF1,PNMA2,GFRA1,CRCP,GLS,TNRC6A,GPR19,RFFL,GRIN2D,FICD,IDH3A,ZIC5,RBPJ,TJAP1,SLC35G1,KCNH2,KCNJ10,GIT1,DBNL,C10orf105,NBL1,NFYA,CHAMP1,PAX6,PDE4D,PIK3CD,ZNF655,PLEC,SLC25A23,PMP2,MINDY2,CRLS1,MAPK9,NCR3LG1,PTK2,RAB3A,ERI2,ALG9,RPL15,GLDN,EMID1,SEMA6D,ATXN1,MRAS,KIF16B,CHD9,ZNF365,SLC6A9,SIRT2,MYH15,ANKRD36,SNCA,FAM126B,SAMSN1,NXT2,ZC3H4,ADAMTS17,NSD1,ARHGEF12,CYB561A3,ZNF106,TLR4,RUSC1,TSN,HSPBP1,PMEPA1,ZXDA,DNALI1,PRDM8,PARP11,RSPRY1,SSPN,FXR1,GAN" MicroRNA hsa-miR-555:mirSVR_highEffct hsa-miR-555:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.59E-33 1.45E-29 6.58E-33 6.07E-32 96 451 "KCNH8,CLK4,TKTL1,UNC5A,KIDINS220,MTUS1,HECW2,CARNS1,PHF12,ASPH,TMEM108,BACH1,BCHE,CALB2,PTBP2,CCKBR,CCPG1,CHN2,CASC2,DNAJB5,MAP4K4,NIPBL,NCOR2,CFAP61,ARHGAP24,DCAF8,ZEB2,MAGI2,ZC3H11A,GRIN3A,ABCC9,RASGRP1,TENM1,PAN3,CEP78,KIAA1109,FGF11,IP6K2,ATP13A4,USP16,DISC1,TXNL4A,GPD2,GRIA4,GRM2,WIF1,IDH3B,RBPJ,KCND2,CREG2,IPO5,NCOA7,MAP2,MRPL42,SESN3,SAMD14,NELL2,NTRK2,CHAMP1,PAK3,NALCN,CCSER2,HMGCLL1,PLTP,FA2H,RASGEF1B,CNNM2,RET,ERI2,RGS3,SEC61A2,EXD2,GSTCD,CSRNP3,BCAN,SLC1A6,LRRC55,SLIT1,SMARCE1,SOX5,ZC3H13,ADHFE1,VWA3A,SATB2,WDR7,GPRIN3,FRYL,AHCYL2,TP53BP2,TPM1,ZNF384,DNAJC12,TRIM9,PARP6,FIP1L1,LINC00632" MicroRNA hsa-miR-874:mirSVR_highEffct hsa-miR-874:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.90E-33 1.63E-29 7.37E-33 6.79E-32 92 417 "NCKAP5,GALNT13,ADD2,SLC12A5,SORCS1,KIAA1324,TXNDC16,CARNS1,PHF12,ALS2,ARNTL,INSYN2B,DYNLL1,N4BP2L1,BARD1,MTMR2,BTRC,CACNB2,KALRN,SPAG9,LDB2,AIFM1,CIART,PLEKHB1,DNAJB5,AKAP7,COL9A2,CPS1,HAPLN1,CNTNAP2,COPS7A,MAGI2,RHOBTB1,GRIN3A,DTNB,C3orf18,TUBD1,GORAB,SPECC1,PHYHIPL,MEGF11,GLDC,PCDH11X,LPAR4,GRIA4,RFFL,GRIK2,GRM7,AP4S1,IGFBPL1,ARHGAP12,MAT2A,MOG,SESN3,MXI1,NRCAM,NUCB2,PAK3,ZNF655,EXOSC10,PPP3CB,PIGG,ZSCAN2,PLEKHB2,ATG16L1,OXR1,RGS4,GSTCD,RORB,ABCA11P,COPZ1,ZFP30,PAAF1,PPP4R3A,YPEL4,CPEB4,RIMS1,UNC80,GSE1,ADGRL3,SATB2,HIF3A,THRA,ELP5,BEST1,TRIM9,PRDM8,DOCK8,PAK5,RSPRY1,MSRB3,DPF3" MicroRNA "CTGAGCC,MIR-24:MSigDB" "CTGAGCC,MIR-24:MSigDB" MSigDB 2.91E-33 1.63E-29 7.39E-33 6.80E-32 66 216 "RNF150,LRFN2,TAOK1,PCDH10,OGT,MARK4,BCL2L2,BSN,HAP1,VXN,HIP1R,RHBDL1,MAGI1,CNTFR,COL11A2,RASSF2,MATR3,KLHL3,SRGAP3,TMCC2,SLC12A6,FAM78B,PHF20L1,SCML2,DLC1,FGFR3,AMOTL2,IP6K2,ARPP21,SESN1,PCDH17,RNF165,SCRT2,INPP5B,KCNK2,SFXN5,MMP16,MXI1,NELL2,NEUROD1,PDGFRA,MBOAT7,MAPK7,PTPRD,RAB5B,TNFRSF19,DHX30,WDTC1,KIF21B,DDN,TAB2,POGZ,NEK4,SYP,SEMA4A,SZT2,ATP13A2,TMEM9,PLPPR2,VAV1,NSD2,SLC26A10,ZXDA,PARP6,GAL3ST3,NAV2" MicroRNA "AAAGACA,MIR-511:MSigDB" "AAAGACA,MIR-511:MSigDB" MSigDB 3.54E-33 1.99E-29 8.99E-33 8.28E-32 62 190 "SLITRK1,ADGRF5,ALCAM,PCDH10,AQP6,SPTBN4,DDX3Y,ATP2B2,CALM1,CDH2,FOXN3,NRXN3,CLTC,QKI,MAP4K4,CREM,C1QL2,ST18,SRGAP3,RPS6KL1,ELAVL3,DCTN4,EYA1,FGF13,CELF1,GAD2,MSTN,GFAP,PCDH17,PPARGC1A,TNRC6A,EML4,HAS2,HLF,KCNMA1,CNOT4,NTRK2,CDK14,NXPH1,MDGA2,KHDRBS2,REV3L,ROBO2,SEMA6D,SCN4B,SORCS3,SMARCE1,ZCCHC24,CDK19,SS18,RGL1,SYT11,CAMTA1,SATB2,TRIM2,FNDC5,UBE2H,CFAP298,PMEPA1,FIP1L1,ADAMTSL3,VANGL2" MicroRNA hsa-miR-18b:PITA hsa-miR-18b:PITA_TOP PITA 3.54E-33 1.99E-29 8.99E-33 8.28E-32 62 190 "ADD3,GPR158,ALCAM,DPP10,CNTNAP1,NCOA1,SYNGR3,CDC42,CCPG1,FOXN3,TBPL1,CLOCK,CLIP3,SOCS5,RIMS2,ST18,DOCK4,PHF19,KIAA0513,ALKBH8,SLC12A6,EPB41L1,ATP8A1,SUCO,OGA,GAB1,WASF3,GLRB,ATXN2L,HLF,HSF2,SOWAHA,IGF1,KCNA1,KIT,INSYN2,MBNL1,MEF2C,MDGA1,PDE4D,PDE1B,GNG2,POU6F1,SNRK,RBBP8,CSRNP3,ATXN1,CCDC88A,IGSF9B,FNBP1,TEX2,BEX1,CDK19,CLASP2,NXT2,TRIM2,PSD3,FRYL,DICER1,DAAM2,TPM3,CADM2" MicroRNA hsa-miR-219-2-3p:PITA hsa-miR-219-2-3p:PITA_TOP PITA 3.54E-33 1.99E-29 8.99E-33 8.28E-32 62 190 "ABAT,CCDC85A,ERMN,HACE1,PTBP2,CAMK2G,MAGI1,CHN2,KMT2C,OSBPL3,APPL1,DOCK4,DBT,G3BP2,MTX3,DSCAM,GPHN,ATP8A1,KIAA1109,ANKFY1,PSD2,NBEA,FUT9,TVP23A,NTNG2,GRIA4,GRM1,MIER3,HNRNPK,HSP90AA1,IGF1,C5orf24,OLFM3,MEIS2,AFF1,MXI1,MYO5A,NFIA,HCN1,FAT3,MAPK8,TMEM260,USP47,KHDRBS2,SCN3A,SCN8A,FNDC3A,NLGN1,BTBD3,SEPHS1,SLC12A2,SNAP25,SSTR2,EPB41L3,ARHGEF9,SYT1,TCF4,RPGRIP1L,UGT8,PMEPA1,GOPC,CBLN2" MicroRNA hsa-miR-18a:PITA hsa-miR-18a:PITA_TOP PITA 3.54E-33 1.99E-29 8.99E-33 8.28E-32 62 190 "ADD3,GPR158,ALCAM,DPP10,CNTNAP1,NCOA1,SYNGR3,CDC42,CCPG1,FOXN3,TBPL1,CLOCK,CLIP3,SOCS5,RIMS2,ST18,DOCK4,PHF19,KIAA0513,ALKBH8,SLC12A6,EPB41L1,ATP8A1,SUCO,OGA,GAB1,WASF3,GLRB,ATXN2L,HLF,HSF2,SOWAHA,IGF1,KCNA1,KIT,INSYN2,MBNL1,MEF2C,MDGA1,PDE4D,PDE1B,GNG2,POU6F1,SNRK,RBBP8,CSRNP3,ATXN1,CCDC88A,IGSF9B,FNBP1,TEX2,BEX1,CDK19,CLASP2,NXT2,TRIM2,PSD3,FRYL,DICER1,DAAM2,TPM3,CADM2" MicroRNA hsa-miR-510:PITA hsa-miR-510:PITA_TOP PITA 3.58E-33 2.01E-29 9.07E-33 8.36E-32 54 141 "LRFN2,GPRASP2,SLC4A4,ATP2B1,C5,CAMK2G,LDB2,REPS2,MAGI1,FOXN3,DNAJB5,CREB5,CLIP3,MATR3,ZC3H11A,DMD,DNAJB6,EDNRA,PHC2,RCAN2,EPHB1,MRVI1,IP6K2,GATM,GFRA1,TTBK1,COQ10A,ARHGAP19,HLF,MAT2A,MBNL1,MYO6,NOVA1,TMOD2,ANKRD16,SDK2,TNPO2,PPP2R5E,RET,RORB,HUNK,FNIP1,ST8SIA1,PPP4R3A,SLC8A1,TRIM67,FAM168A,PUM2,CCDC136,SF1,POLR3H,DNALI1,KAT6A,ST8SIA2" MicroRNA hsa-miR-337-5p:mirSVR_lowEffct hsa-miR-337-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.79E-33 2.13E-29 9.60E-33 8.84E-32 86 368 "AXIN2,RNF150,MTA3,AGT,KCTD16,SPOP,GOLGA7B,CDC42BPA,LCORL,AQP4,BLM,MMD2,CLCN4,HECTD1,IQCK,CNRIP1,CREM,SNCAIP,SUSD5,VCAN,EDRF1,EARS2,PABPC5,PITPNC1,ZEB2,COPS7A,SNAP91,KBTBD11,DLG4,RAB39B,ABCC5,C3orf18,PIPOX,TOMM40L,SMC2,PRELID3A,NEK6,GLS,GRIA4,AP4S1,FAM95B1,C5orf24,RBPJ,NCOA7,MBD1,MEIS2,MID1,MYT1,HNRNPM,NFYA,TBC1D25,PDE1C,PNMA3,MED1,FEZF2,CYB561D1,YY1AP1,SNX22,ABCA11P,KCNIP3,CLIP1,TNFRSF19,COPZ1,ITSN1,KIF16B,ST6GAL1,ENKUR,NPAS3,ITPRID2,ZSCAN29,NECAB1,VPS13A,ATP11A,CAMTA1,FAM208A,ALG1,TPCN2,CLASP1,DICER1,AKTIP,TIMP4,TLR4,TP53BP2,ZBTB14,EML6,ACTR3B" MicroRNA hsa-miR-1249-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.83E-33 2.15E-29 9.71E-33 8.95E-32 74 274 "DPF1,ELFN2,ADCY5,RNF157,ADD2,CASKIN1,SORCS2,PHF12,PPFIA3,TTLL9,HAP1,CANX,TMEM184B,BTF3L4,NCOR2,KIAA0513,IP6K1,SPATA2,SEC16A,CHRDL1,SYT15,EPB41L1,DMTN,MTSS1L,RTN3,WAC,FGFR1,DOT1L,HBS1L,SRCAP,GLYR1,STARD3,ZBTB49,ZNF491,SHISA6,SOWAHA,NKD1,STMN1,SESN3,NBL1,NFIX,NOVA2,TBC1D25,PDE4A,GPR173,CDK14,PKM,TNPO2,POLR2F,PPARA,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,PEX26,TRIM67,CAMTA2,STX1A,ASTN2,GPRIN3,HHIP,NACC2,ZFP91,KCTD2,WBP2,TUBB2A,MGAT5B,CLDND1,ZNF70,INTS3,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-28-5p:mirSVR_highEffct hsa-miR-28-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.85E-33 2.16E-29 9.75E-33 8.98E-32 117 648 "SDE2,ACADM,ACHE,AS3MT,RNF150,SLC44A5,HACE1,BEGAIN,AMPH,ZFAT,OGT,PPFIA1,SEMA4G,ASPA,CACNA1G,PTBP2,CAMK2D,CCKBR,ZBED1,SRSF11,TJP2,CNTFR,PREPL,GDA,SNCAIP,OSBPL3,NCAN,FAM169A,RIMS2,GAPVD1,TMEM170A,GIT2,MED24,SMG7,SV2B,NTM,DLX1,DYRK1A,ABCC5,YAF2,ELAVL2,EN2,LRRC23,EPHA5,FABP7,FGF1,NSG1,DLL3,AP4B1,GAD2,MTHFD2,NEU3,GPD2,GPM6A,GPM6B,GRIA2,PLCD4,ADAMTS13,LINC00839,GSTT2,ATXN2L,HNRNPK,IGFBP1,KIF5A,MAT2A,MEST,NELL1,SLCO1C1,NFE2L2,DNHD1,ZNF655,HMGCLL1,SAMD9,GON4L,MDGA2,PIGG,TMEM260,ZIK1,C1orf109,ZNF615,MARCH1,FAT4,MSANTD2,RDX,NUDT11,RPRD1A,GSTCD,YY1AP1,ARMH4,LRRK2,CASC3,ITSN1,SEC31A,ABLIM3,EPN2,PKNOX2,SIRT2,SHANK2,ZFP1,MAST1,SNAP25,MYO16,TNIK,RGL1,ADHFE1,DMXL2,TMEM9,ELP5,SLC13A3,ANKS1B,DHX33,PRDM2,PCDH15,KAT6A,PHTF2,JMJD1C,NLRP3" MicroRNA hsa-let-7a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.29E-33 2.41E-29 1.09E-32 1.00E-31 116 639 "CDC7,FZD9,MTUS1,ZNF578,USP35,AMPD2,APP,AQP6,IGDCC4,ATP2A2,ATP2B1,ALDH7A1,BACH1,BMPR1B,JAZF1,ZNF555,CAMK2D,METTL6,FMNL3,CDC25B,CFL2,SYNPR,QKI,MAP4K4,NIPBL,CRY2,CS,PDE4DIP,DNAL1,DNAJC6,SMG7,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EGFR,EGR3,EIF4G2,PLEKHO1,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,JPH4,SALL3,DISC1,GATM,NEU3,SESN1,TCERG1,GLUL,POLL,LILRB4,GPM6B,FUT10,CNTRL,RABL2A,ATG4C,HAS2,ATXN2L,HSF2,IL6R,KPNA5,PAXBP1,NAT8L,MDM4,MEIS1,THYN1,MYO9A,NAP1L1,NEFM,NME4,NPTX1,SLC11A2,NUCB2,OPRL1,PIK3R1,PKM,POU3F2,QDPR,USP47,BSDC1,RDX,FIGN,RAVER2,ATXN2,FNIP1,KIF27,COPZ1,SHMT2,FNDC3A,CAND2,PEG10,MCF2L2,TAB2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,DICER1,TGFBR3,CBX5,RBFOX2,TRIO,TUBB2A,SLC35A4,VAV2,ZNF28,SMARCAD1,C12orf4,FAM13C,PHTF2" MicroRNA hsa-miR-1915:mirSVR_highEffct hsa-miR-1915:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.35E-33 2.44E-29 1.10E-32 1.01E-31 95 445 "CLK4,PTCHD1,AP2A2,SNX32,ALAD,AMT,LGR5,CADPS,DACT3,NCOA1,CFLAR,BTK,DDR1,VXN,SPAG9,IGFN1,CNTN1,MYRIP,GDA,CS,OSBPL3,FRMPD4,TBC1D5,IP6K1,SPATA2,DLG2,DNM2,HEYL,RCSD1,FAM198B,TOMM40L,FOXG1,HHIPL1,ARPP21,CRCP,COPS8,MSL3,GRM8,FAM19A2,IL1RAPL1,IRAK3,VSIG4,ZNF678,KCNC2,MGAT3,MID1,DBNL,MYO7A,TBC1D25,PBX1,PDGFRA,SSH1,PLCL1,TATDN3,TMEM260,RFX5,ARMC5,YY1AP1,PRR5L,SYNDIG1,TRAPPC13,ITSN1,HKDC1,FHOD3,SLITRK3,ZNF365,PREX2,SLC12A4,SMARCD3,KIF13A,NKAIN2,VAMP1,SYN1,DNMBP,VWA3A,WSCD1,RPGRIP1L,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,KHDC1,DAAM2,PRRT1,FNDC5,SYNC,PRDM8,LMAN2L,URM1,CASC15,NHSL1" MicroRNA hsa-miR-3141:mirSVR_lowEffct hsa-miR-3141:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.89E-33 2.75E-29 1.24E-32 1.14E-31 99 481 "SYN3,OLMALINC,BEGAIN,AMPD2,LRFN1,SUGT1P4-STRA6LP-CCDC180,CDK5R1,CALB2,TRIM41,RHBDL1,NFS1,ASIC3,EPS15L1,NRXN3,PPT2,MYL6B,NGEF,MAP4K4,IGLON5,ZNF385A,CST3,CTNND1,DBN1,ARMCX4,ELMO1,SMG7,SEZ6L2,PHC2,RASA4,SEZ6,MRPL37,RTN3,TUBB3,TUBB4A,CORO2B,BAIAP2,AKAP3,POMT1,TMEM107,PDLIM5,RASL10A,CAMKK2,DLL3,HHIPL1,NRG3,ATP8A2,ACSS1,GRIN1,GRM7,LINC00839,RNF165,UBE2QL1,ARHGAP19,SHISA6,CELF5,TJAP1,IL11RA,METTL21A,LRRC4B,MAT2A,NRBP2,ZNF862,PCBP3,ZDHHC8,GDAP1L1,NALCN,SMOX,FXYD1,CDIP1,PACSIN1,DIRAS2,CNNM2,BCAS3,SIDT1,ROGDI,TRIM68,RGS12,ATXN2,ASIC4,SCG5,ST3GAL3,FAM81A,PEX26,LGI3,MAST1,RCOR3,MAPKBP1,TBL1X,WDR7,ARHGAP9,GALNT17,TMEM9,NR2E1,LAT2,GUSBP1,MAP3K12,WNK3,ST7,RNF170" MicroRNA hsa-miR-331-5p:PITA hsa-miR-331-5p:PITA_TOP PITA 5.49E-33 3.08E-29 1.39E-32 1.28E-31 54 142 "ASIC1,ARHGAP5,SYNJ1,DLGAP2,IGDCC3,AKAP12,KIAA0408,DCAF8,DBT,JAKMIP2,RUSC2,SRGAP3,RASGRP1,PAN3,EPS8,WAC,FOXG1,USP16,FUT9,PHYHIPL,ARFIP1,GRM1,HAS2,ELOVL5,DHX35,PLD5,INSM1,ITGAV,GPR155,MBNL1,SYT9,SHC3,MEF2C,MYCN,CNOT4,HCN1,PCDH9,PCSK2,RANBP3L,RBBP8,RORB,ATXN1,SOX11,ELOVL4,RPGRIP1L,TCF12,SIRT1,KAT6B,PITPNB,ZIC3,LYPD6,CELF4,RNF103,RNF170" MicroRNA hsa-miR-720:mirSVR_lowEffct hsa-miR-720:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.66E-33 3.18E-29 1.43E-32 1.32E-31 97 464 "DGCR6,GPRIN1,LTBP4,CDK10,CCAR2,ATP1A2,DPY19L3,ADGRB2,SNAI3-AS1,NRP2,ARHGEF7,CASTOR3,MMD2,CACNA1A,CACNA1D,CALB2,BRSK2,SPAG9,USP6,CACNA2D2,LHX2,KMT2C,NRXN3,COL9A2,SLC4A8,CRY2,RGS6,NRSN1,INTS1,SPOCK2,CNIH3,DNM1,RPS6KL1,DPH1,SPEG,CLVS1,RPS6KC1,FCGRT,FGF14,SEPT9,TUBGCP4,USP19,STARD3,WDFY3-AS2,GRIA1,GRM2,ZNF496,KCNJ16,KCNK2,KHK,LAMP2,NCOA7,MN1,PCSK5,KCTD15,PLCD1,ANKRD16,IRX1,PCDHB17P,VSTM2L,PRKCZ,SIDT1,PTK2,PTPRB,SETD5,CCDC25,SCN4B,SH3GL3,ARFGAP1,RIMS1,SCN3B,ZCCHC24,ZSWIM8,ATP10B,PBLD,MAPK8IP3,CAMTA1,USP32P1,SLC44A1,PIK3R5,TPM2,SMUG1,TTC3,SGK3,GORASP1,PLPPR2,ATP6V0E2,SH3GLB2,PRDM2,TMEM178A,NAV2,SNX27,PCBP4,DOCK8,ZNF248,TIGD6,SPATA13" MicroRNA hsa-miR-876-5p:PITA hsa-miR-876-5p:PITA_TOP PITA 5.78E-33 3.25E-29 1.46E-32 1.34E-31 63 198 "ASIC1,XKR4,SLITRK1,AXIN2,PCDH19,TAOK1,SEMA6A,OGT,DPP10,PPFIA3,RNF182,MTMR3,JAZF1,QKI,SNCAIP,GAPVD1,DBN1,MAGI2,MTX3,RCAN1,DYRK1A,ELAVL2,ELAVL3,NRN1,WAC,ZIC4,NPTN,CAMKK2,B3GAT1,FAXC,ARFIP1,SESN1,GK,GLDC,GPM6A,KLF12,NEGR1,KCNMA1,KCNN3,KIFC3,MAT2A,MBNL1,MEF2C,MN1,NAP1L1,NAP1L3,CLDN11,PMP22,MED1,PTPRD,CEP97,RIMKLA,ATXN1,MAGI3,SLC6A1,TMCC1,SOX5,SS18,EHBP1,CUX2,FAM155A,REEP1,SOCS4" MicroRNA hsa-miR-1183:PITA hsa-miR-1183:PITA_TOP PITA 5.78E-33 3.25E-29 1.46E-32 1.34E-31 63 198 "PTCHD1,ZNF608,RTL9,TAOK1,CDC42BPA,ANK3,APC,CADPS,ZBTB10,KALRN,LGI1,SRSF11,QKI,HECTD1,CNN3,CREM,PLCXD3,DNAJC6,DLG2,SEZ6L2,RGS17,SUCO,HPCAL4,SGIP1,STAG2,GABRB3,NCKAP1,MSTN,PCDH17,GHR,PCLO,GRIA2,MAEL,NEGR1,AGFG1,ITGAV,KCNA2,LRP1B,MID1,NELL1,PDE4B,KCTD15,LRRN3,PTCH1,PTPRD,PTPRO,ARID4A,ZYG11B,RORB,ATXN2,TMCC1,SPTB,NKAIN2,TCF4,PSD3,TJP1,DAAM2,TRPS1,OSBP2,FZD3,HNRNPA3,VANGL2,SOCS4" MicroRNA hsa-miR-584:PITA hsa-miR-584:PITA_TOP PITA 5.88E-33 3.30E-29 1.48E-32 1.37E-31 61 185 "OSBPL6,ANK3,USP37,AQP4,CADPS,LDLRAD4,RUNX1T1,B4GALT6,AKAP6,MYRIP,NCOR1,RGS6,PUM1,GAPVD1,DNAJC6,USP3,FAM78B,E2F5,ELAVL2,ERBB4,WAC,ACSL4,MEX3B,TBR1,STAG2,DNER,HSF2,C5orf24,KIF2A,MAP2,MEIS2,SCAMP5,MITF,MXI1,NEXMIF,NF1,HCN1,PCMT1,OLA1,PRRX1,PKN2,TTC13,ZNF493,ZYG11B,REV3L,SETD5,FBXW7,CNKSR2,SLC20A2,RIMS1,PALLD,HECW1,SRPK2,SYT11,FBXW11,DOK6,STXBP4,FLRT2,TBC1D15,ZIC1,ZIC3" MicroRNA hsa-miR-516a-3p:PITA hsa-miR-516a-3p:PITA_TOP PITA 7.01E-33 3.94E-29 1.77E-32 1.63E-31 65 212 "ASIC1,SLITRK1,SORCS1,ATP2B1,LDLRAD4,CACNB4,CDH18,CCPG1,CREB5,RIMS2,FRMPD4,TM9SF4,ZEB2,DPP6,EFNB3,MBNL2,DCTN4,EN2,ETV1,MEX3B,PCDH17,EML4,PCLO,GRIK3,HLF,USP54,KCNN3,MEF2C,NEXMIF,MYT1,NCAM1,OPCML,RASGEF1B,PTPRN2,GTDC1,S100B,SCP2,SH3GL2,SLITRK3,TET1,PEG10,SPTB,KIF1B,PLCB1,SYT1,SYT4,UNC5D,TCF4,SATB2,ZEB1,TCF12,CLASP1,SLC44A1,NR2E1,TNR,TUB,TMEM237,ZNF189,ADAMTS9,NAV3,WIPF2,RGS7BP,KAT6A,ADAMTS10,SOCS4" MicroRNA hsa-miR-365a-3p:TargetScan hsa-miR-365a-3p TargetScan 9.49E-33 5.33E-29 2.39E-32 2.20E-31 75 285 "ADAR,ADCY6,ADD3,PTCHD1,PITPNM2,ANK3,PHF12,PPFIA2,RGS20,ARRB2,RNF182,FOXK1,PTBP2,DLGAP2,BTF3L4,CREB5,NCOR1,CS,DOCK4,GAPVD1,HDAC4,DLG3,NR1D2,DTNA,ELAVL2,RGS17,EPS8,ETV1,EFEMP1,MED12L,FGF1,NCKAP1,MALT1,GPM6A,RAPGEF4,NR3C1,RASSF8,HAPLN2,HMGCR,NKD1,KCNA1,KCNH2,KCNJ3,LAMP2,LRP1B,MEIS1,NFIA,P2RY1,PAX6,PCDH8,PCSK5,PDE4D,PDYN,BEST3,EPN1,KANSL1,PPP5C,GRAMD1C,PLEKHB2,DPF2,REV3L,ROBO1,SALL1,ATXN7,CHD9,EPC1,KDM3A,PEG10,ANKRD28,SATB2,HHIP,CSMD1,NR2C2,RICTOR,FZD3" MicroRNA hsa-miR-365b-3p:TargetScan hsa-miR-365b-3p TargetScan 9.49E-33 5.33E-29 2.39E-32 2.20E-31 75 285 "ADAR,ADCY6,ADD3,PTCHD1,PITPNM2,ANK3,PHF12,PPFIA2,RGS20,ARRB2,RNF182,FOXK1,PTBP2,DLGAP2,BTF3L4,CREB5,NCOR1,CS,DOCK4,GAPVD1,HDAC4,DLG3,NR1D2,DTNA,ELAVL2,RGS17,EPS8,ETV1,EFEMP1,MED12L,FGF1,NCKAP1,MALT1,GPM6A,RAPGEF4,NR3C1,RASSF8,HAPLN2,HMGCR,NKD1,KCNA1,KCNH2,KCNJ3,LAMP2,LRP1B,MEIS1,NFIA,P2RY1,PAX6,PCDH8,PCSK5,PDE4D,PDYN,BEST3,EPN1,KANSL1,PPP5C,GRAMD1C,PLEKHB2,DPF2,REV3L,ROBO1,SALL1,ATXN7,CHD9,EPC1,KDM3A,PEG10,ANKRD28,SATB2,HHIP,CSMD1,NR2C2,RICTOR,FZD3" MicroRNA hsa-miR-8085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.79E-33 5.50E-29 2.47E-32 2.27E-31 84 356 "DPF1,CPNE2,ELFN2,HACE1,TAOK1,PDZD4,KIF6,PPFIA4,PPFIA3,CDC14B,SFMBT2,SEMA4G,ASPH,DDX3Y,ADGRB2,HAP1,FMNL3,ARHGEF2,CHRNB2,EPS15L1,CLU,ARHGEF6,SUMF2,BTF3L4,RGS6,MICAL2,KIAA0513,TM9SF4,PHYHIP,SGSM2,CHRDL1,ABCC5,MRO,ING4,ELAVL3,MTSS1L,FGFR1,AMOTL2,AFF2,NCKAP1,GLYR1,GLUL,RAPGEF1,MIER3,SHISA6,IDH3A,SLC6A17,KCNK3,MDFI,PPM1L,SAMD14,PABPC1L2A,ZC3H12B,GPR137C,PDE4A,KCTD15,FTO,SDK2,PPARA,SLC22A23,PTPRE,NKAIN1,MORC4,RNH1,SETD5,MYH14,SOX6,CCDC88A,ATF7IP,WDTC1,SP2,ERC1,IQSEC2,ZSCAN29,AJAP1,FAM168A,ARC,ASTN2,HHIP,TMPRSS5,TUBB2A,ZNF70,SIGLEC10,ACTR3B" MicroRNA hsa-miR-423-3p:mirSVR_lowEffct hsa-miR-423-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.07E-32 6.01E-29 2.70E-32 2.48E-31 89 398 "SLC12A5,ADRB2,PLA2G6,CARNS1,AMPD2,LRFN1,PHF12,CDK10,ATP1A2,ATP1B3,CADM3,CA8,CCKBR,USP6,CDH8,DLGAP1,CHGA,FEZ2,CFAP61,SIRPA,LYPD1,USP3,DNAH9,CD99L2,CDON,DMTF1,DPYSL2,EDN1,EDNRA,EIF4G1,EPHB1,CD320,ZNF589,PRKAG2,MEX3B,SLC37A3,BRPF3,DISC1,GCNT2,GFAP,ZNF638,LOXL3,PRLHR,GRM7,LINC01551,KCNJ10,LAMP2,LOC100128239,IL17D,GIT1,PTOV1,DNHD1,IGSF11,HERC2P3,FTO,POLR2F,POU6F1,MAPK7,PSMD13,UHRF1BP1,PTK2,STK32A,NKAIN1,ARHGEF10L,MRPS18A,SEC61A2,RNF220,ATAT1,TMEM156,CCDC92,PKNOX2,SLC14A1,ARFGAP1,CDK5RAP2,MAPKBP1,SSPO,NSFL1C,JMJD6,KAZN,DOCK9,SPX,TIAM1,TMPO,VLDLR,KLC2,TMEM237,PRDM2,FIP1L1,PDSS2" MicroRNA hsa-miR-4284:mirSVR_highEffct hsa-miR-4284:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.19E-32 6.69E-29 3.00E-32 2.76E-31 98 477 "RALGAPA1,ACADM,MTUS1,GPR158,CC2D2A,FAM135A,PARG,TNRC6C,STK33,ZNF599,NAE1,CACNA1D,SYT6,SCARB1,SYNPR,NRXN3,SH2B1,CSF1,CSF2RA,MICAL2,ERC2,MAGI2,SGSM2,EXOG,SLC25A18,DNAJB6,AASDH,TMEM35A,CORO2B,SPSB4,AGAP3,FOXM1,GAD1,NEK6,SULT1C4,AHDC1,GNAS,GRIA2,MFSD2A,RABL2A,FAM107A,RNFT2,ADAMTS6,ZNF491,HSP90AA1,FAM95B1,INPP5B,KCNMA1,KLC1,MATN3,COL28A1,NASP,SNTG1,PDE3B,RETREG1,JAKMIP1,ING3,GDPD1,MASP1,SIDT1,GON4L,ELOVL2,PTPRO,TMEM231,ACSS3,RAD52,GAL3ST4,UEVLD,RXRG,FERMT1,MAGI3,FNDC3A,NUBPL,RUFY2,ELMO2,TET1,MYH15,ZC3H13,ZC4H2,ZFR2,SYN2,PCDHB6,SIK3,ATP13A2,NPL,STXBP4,RPL7L1,WIPF1,XPO1,XRCC4,ZNF24,TRIM9,MKRN3,PRDM2,DOCK8,ZNF248,RNF170,IFT88" MicroRNA hsa-miR-411-3p:TargetScan hsa-miR-411-3p TargetScan 1.31E-32 7.36E-29 3.29E-32 3.03E-31 65 214 "C3orf14,RNF150,ALCAM,C6orf89,APBB2,APP,INSYN2B,NOL4,DOCK11,CACNA1E,CDH2,NRXN3,ARMC8,AKAP5,PLCXD3,PYGO1,MATR3,KIAA0087,ELMSAN1,ENPP6,ERBB4,SEC24B,ATP6V1H,MSANTD4,PHYHIPL,JPH4,KDM2B,RAPGEF1,IL1RAPL1,PSIP1,FRMD5,BACH2,KCNB1,KCNN3,CHIC1,MEIS1,MTTP,HCN1,OPCML,P2RY1,KCNK10,GPR173,GNG2,SDK2,PPP2R2C,ANKHD1,PTPRD,GTDC1,RPE,SALL1,SATB1,FAM19A1,HSPA4L,NLGN1,MPRIP,CLASP1,AP4E1,HHIP,CBX5,RGMB,CADM1,FZD3,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-379-3p:TargetScan hsa-miR-379-3p TargetScan 1.31E-32 7.36E-29 3.29E-32 3.03E-31 65 214 "C3orf14,RNF150,ALCAM,C6orf89,APBB2,APP,INSYN2B,NOL4,DOCK11,CACNA1E,CDH2,NRXN3,ARMC8,AKAP5,PLCXD3,PYGO1,MATR3,KIAA0087,ELMSAN1,ENPP6,ERBB4,SEC24B,ATP6V1H,MSANTD4,PHYHIPL,JPH4,KDM2B,RAPGEF1,IL1RAPL1,PSIP1,FRMD5,BACH2,KCNB1,KCNN3,CHIC1,MEIS1,MTTP,HCN1,OPCML,P2RY1,KCNK10,GPR173,GNG2,SDK2,PPP2R2C,ANKHD1,PTPRD,GTDC1,RPE,SALL1,SATB1,FAM19A1,HSPA4L,NLGN1,MPRIP,CLASP1,AP4E1,HHIP,CBX5,RGMB,CADM1,FZD3,JMJD1C,FXR1,NETO1" MicroRNA hsa-miR-6129:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-32 8.11E-29 3.63E-32 3.34E-31 77 302 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,SF1,ZIC2,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-325:mirSVR_highEffct hsa-miR-325:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-32 8.83E-29 3.95E-32 3.64E-31 91 417 "ACADM,KCTD16,TAOK1,USP28,ARNTL,RAB29,KALRN,CDH2,SULT4A1,MAGED1,ACBD5,SEC31B,CSNK1G3,PLXNA4,LIN54,RHOBTB1,DNAH9,DPYSL2,EDN1,SYT15,MBNL2,STX2,SRRM1,WAC,CORO2B,ZSCAN30,EFCAB2,CELF1,STAU2,NRG3,ILDR2,DNER,TUBGCP4,LNX1,TDRKH,CECR2,GRIA4,SOX21,MAEL,HAS2,HNMT,LIX1,KCNN2,STXBP5,MAP2,MARK1,POC1B,ZNF680,NCF2,NDUFA5,LOC100128398,PDE4D,GPR85,BEST3,PFKFB3,ZFYVE21,FAM216A,PMP22,PRKAB2,RAB39A,GRAMD1C,HYDIN,GAL3ST4,RET,GTDC1,TTLL7,TMEM206,LGR4,ATXN2,FAM19A1,ITSN1,FHOD3,ARHGEF40,CDK5RAP2,RIMS1,TMCC1,TNIK,NKAIN2,SYT1,ANKRD28,KLHL4,ANO4,SATB2,PRR18,HIRA,CADM1,RNF103,WNK3,PAK5,ZNF248,RNF146" MicroRNA hsa-miR-3606-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-32 9.29E-29 4.15E-32 3.83E-31 61 188 "FZD9,SPOP,ASCL1,ATP2B1,ZNF582,SLC2A11,BACH1,NIPA1,ZNF555,MAP7,HS3ST5,HDAC4,DCC,EDN3,ENPP6,SGIP1,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,NAP1L1,SNTG1,CCSER2,KANSL1,PRKACB,UHRF1BP1,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,SRPK2,CEP68,TCF7L2,PSD3,DICER1,HHIP,TRPS1,SF1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-409-5p:mirSVR_highEffct hsa-miR-409-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.82E-32 1.02E-28 4.58E-32 4.22E-31 74 280 "KCTD16,CCDC146,LGR5,DPY19L3,TIGD7,SRSF11,CHM,DGCR9,TMEM155,ARHGEF6,LETMD1,ATRNL1,CST3,PUM1,ZFYVE16,DGKG,DNAJC6,SPOCK3,OLIG1,DYRK1A,DNM1L,FSD1L,KMT5B,NCALD,RRAGB,STAU2,ABLIM2,PHYHIPL,STAG2,HBS1L,FREM1,PPARGC1A,WDFY3-AS2,GPM6A,SERP2,LIX1,METTL21A,KCNK1,MOBP,SNTG1,PURG,SPATA6,MINDY2,HYDIN,RELN,ANKHD1,RFX2,NEK11,ATP8B4,ZFP30,FAM214B,KDM4D,SLC12A2,SMARCD3,UNC80,EPB41L3,C12orf76,CAMTA1,SATB2,PCDHB4,FRYL,SLC44A1,NR2E1,TRO,PLEKHH2,TBC1D15,KLC2,ZIC1,ZIC3,FTSJ1,LRP8,KCNAB1,FZD3,NETO2" MicroRNA hsa-miR-4510:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.84E-32 1.03E-28 4.62E-32 4.25E-31 77 303 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,SETD5,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-18b-5p:TargetScan hsa-miR-18b-5p TargetScan 1.85E-32 1.04E-28 4.63E-32 4.26E-31 67 229 "ADD3,KCTD16,ALCAM,DPP10,ANK3,CNTNAP1,NCOA1,INSYN2B,ATM,FUBP1,CDC42,CLCN4,CNR1,NRG2,CLIP3,DOCK4,PHF19,LIN54,PLXNC1,EPB41L1,ERBB2,CEP85L,F3,ATP8A1,FER,FGF1,CAMKK2,GNAS,NR3C1,ATXN2L,HSF2,IGF1,KCNA1,KCNA2,KCND3,KIT,MBNL1,JAKMIP3,MDGA1,PDE4D,PDE1B,CDK14,GPSM2,PRKACB,MAPK4,DIRAS2,RBBP8,GTDC1,ROBO2,RIMKLA,FAM192A,SATB1,CSRNP3,ATXN1,CCDC88A,CDK19,MESP1,NXT2,PSD3,FRYL,DICER1,NACC2,CBX5,DAAM2,CADM2,FZD3,RNF146" MicroRNA hsa-miR-18a-5p:TargetScan hsa-miR-18a-5p TargetScan 1.85E-32 1.04E-28 4.63E-32 4.26E-31 67 229 "ADD3,KCTD16,ALCAM,DPP10,ANK3,CNTNAP1,NCOA1,INSYN2B,ATM,FUBP1,CDC42,CLCN4,CNR1,NRG2,CLIP3,DOCK4,PHF19,LIN54,PLXNC1,EPB41L1,ERBB2,CEP85L,F3,ATP8A1,FER,FGF1,CAMKK2,GNAS,NR3C1,ATXN2L,HSF2,IGF1,KCNA1,KCNA2,KCND3,KIT,MBNL1,JAKMIP3,MDGA1,PDE4D,PDE1B,CDK14,GPSM2,PRKACB,MAPK4,DIRAS2,RBBP8,GTDC1,ROBO2,RIMKLA,FAM192A,SATB1,CSRNP3,ATXN1,CCDC88A,CDK19,MESP1,NXT2,PSD3,FRYL,DICER1,NACC2,CBX5,DAAM2,CADM2,FZD3,RNF146" MicroRNA hsa-miR-361-3p:PITA hsa-miR-361-3p:PITA_TOP PITA 1.99E-32 1.12E-28 5.00E-32 4.60E-31 55 151 "AP2A1,PDZD4,OGT,FAM131A,ATP1A3,BTRC,CACNA2D2,TAOK2,NRXN2,CNTFR,CDC42BPB,SH2B1,FAM131B,ZC3H11A,SV2B,SV2A,DLG2,ABI1,EIF4G1,ELAVL3,ELN,RASGRP2,ANKRD13B,AGAP3,SYT3,DCTN2,CPLX2,BACH2,PACRG,ADAM11,NCAM1,RC3H2,PRRX1,POU3F2,MED1,PPP3CA,FAM120C,USP47,PRRT2,PBRM1,YPEL4,FAM219A,WDTC1,ZSWIM8,TSPYL2,AJAP1,GSE1,SZT2,FBXL16,THRA,RELL2,ZNF384,XPO1,TRIM9,SLC30A3" MicroRNA hsa-miR-6799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-32 1.12E-28 5.01E-32 4.62E-31 119 679 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,DDR1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,PITPNM3,UBXN2A,USP6NL,NOS1AP,MYADM,GAPVD1,KIAA0513,TOMM20,IP6K1,DNAL1,SPATA2,DNAH9,SLC29A4,DUSP9,PHC2,TMTC1,APH1A,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,GLUL,BVES,IRAK3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,IBA57,SLC6A17,SMAD9,MAT2A,MATN3,PPM1L,CCDC80,FXYD6,NBL1,SLC11A2,TBC1D25,ZNF713,PDGFRA,BEST3,PFKFB3,EPN1,RETREG2,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,RTKN,HES6,MYO18A,CLSTN1,SLC1A2,SLC2A5,ZKSCAN3,ZCCHC24,MCF2L2,DDN,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,TUBB2A,RPL7L1,BCL2L13,TSPAN11,KLC2,ZNF708,ZNF17,ZNF28,ZNF70,DPYSL5,EVI5,CIAPIN1,SNX27,PARP11,TMEM63C" MicroRNA hsa-miR-130b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-32 1.41E-28 6.27E-32 5.78E-31 82 344 "AS3MT,GALNT13,NLGN4X,CDC42BPA,USP37,ASCL1,PCDHGB4,PROM1,SPAG9,CD86,LRRFIP1,CRY2,NCOR2,RGS6,RIMS4,CST3,DZIP3,PITPNM3,RIMS3,MAML1,ZC3H11A,CDON,RCAN1,ABI2,ELAVL3,RGS17,EMX2,NRN1,FGF1,HBS1L,RAPGEF6,GALR1,WASF3,SRCAP,SULT1C4,SYNPO,IGF1,ZIC5,GPR155,MID1,CD200,MYBPC1,P2RX7,PDE3A,GDAP1L1,PLCL1,PLP1,PPARA,KANSL1,PRKCB,PIGG,ZSCAN2,ZNF793,TMLHE,ALG9,SPIN3,ACER3,CSRNP3,ATXN7,OGDHL,IGSF9B,EMC1,RBM26,NSFL1C,ANKRD28,EXOC7,PSD3,TGFBR3,HHIP,FBXL16,TNS1,TTC3,FAM181B,TBC1D15,ZBTB38,DPYSL5,MEIS3,SLC30A3,WNK1,NAV2,FRMD6,CBLN2" MicroRNA hsa-miR-876-3p:PITA hsa-miR-876-3p:PITA_TOP PITA 2.67E-32 1.50E-28 6.68E-32 6.15E-31 50 123 "ARID1A,SEMA6A,MTMR3,CALM1,CAMK2G,SYT6,CREB5,FRMPD4,PHYHIP,DLG2,DMD,ABI2,ST3GAL6,BRPF3,PPARGC1A,BRD8,LOXL3,GRIA1,CIT,OLFM3,MEIS1,NEXMIF,GDAP1L1,ANKRD16,MINDY2,PRKCZ,UHRF1BP1,PTPRD,RBBP6,RDX,ZMAT4,LRRTM4,SMPD3,SGK1,PPP1R9A,SMTN,CPEB4,SNAP25,KDM4B,TEX2,POGZ,LRRC4,FAM168A,VAMP1,SYP,PDSS1,UBTF,NAV3,WIPF2,HNRNPA3" MicroRNA hsa-miR-6127:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-32 1.68E-28 7.46E-32 6.87E-31 77 305 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,TPCN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-6133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.98E-32 1.68E-28 7.46E-32 6.87E-31 77 305 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF17,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-3194:mirSVR_highEffct hsa-miR-3194:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.14E-32 1.76E-28 7.84E-32 7.22E-31 86 378 "DGCR6,CSMD3,ADD2,SLC12A5,PWWP2A,SMIM17,SUGT1P4-STRA6LP-CCDC180,GPAM,CASTOR3,CFAP410,KALRN,LARGE1,SYNPR,COG1,CSF2RA,ARHGAP24,ARMCX4,DCT,SNAP91,RAB39B,DNM1,DTNA,AMOTL2,HVCN1,OGA,CAB39,ERAP1,DISC1,PCLO,RFFL,GRM2,SOX21,HP,MSL1,SCIN,KCND2,KIFC3,PAXBP1,ZFYVE27,AQP11,MBNL1,TM6SF1,MOV10,NDP,ZDHHC22,DUSP26,SEMA5B,VSTM2L,PRKAB2,CNTLN,PXK,SLC25A48,RGS12,EPHA10,SPIN3,GLDN,MEG3,ITSN1,KIF16B,HKDC1,FNDC3A,SYBU,ABLIM3,BTBD3,KANSL3,ELMO2,BTBD7,SORCS3,SON,FNBP1,KIF1B,LARP4,CEP68,RGL1,SYN2,ANO4,AZIN2,HIF3A,TEK,DNAH7,DICER1,ZFP91,MEAF6,BEST1,LAMP5,XKR7" MicroRNA hsa-miR-4722-5p:Functional MTI Functional MTI miRTarbase 3.56E-32 2.00E-28 8.90E-32 8.20E-31 110 595 "SDE2,AS3MT,NDRG3,ADAR,ADD2,SLC24A4,CASKIN1,TXNDC16,AMH,PHF12,APAF1,AQP6,CDC14B,SFMBT2,ASPA,ASPH,ATM,ZNF583,BTRC,DDR1,ZNF555,PTBP2,CBS,SLC16A4,CFL2,GPR37L1,NRXN3,CLU,MFSD4A,SLC35F1,CS,IPCEF1,PITPNM3,UBXN2A,RUBCN,MYADM,KIAA0513,TMEM170A,ELMSAN1,BLOC1S6,SLC29A4,GNE,SNX29,SYT15,HEYL,MRNIP,APC2,VPS26C,ZNF585B,KIAA1109,ATP13A4,KBTBD12,MSANTD4,AHDC1,GJB1,CRCP,GPR75,GLUL,ZNF638,KIF3A,BVES,RABL2A,ATOH8,PACSIN2,AGBL5,SHISA6,KCNH2,KCNJ11,KLHL23,KIF5A,SMAD9,MEIS1,PPM1L,MXI1,NFIX,NUCB1,CDK18,PKM,MTRF1L,MTMR10,ZNF844,QDPR,MSANTD2,ALG9,GSTCD,SNX22,PTGR2,HSD11B1L,NCBP3,SEMA6D,IL17RB,SLC2A5,MYH15,IQSEC2,CDK19,FAM168A,FAM208A,MGRN1,SLC19A3,PCDHA6,AHCYL2,HIF3A,TPM3,SSBP2,LRTM2,RPRM,USP1,GDPD5,SNX27,MPPE1" MicroRNA hsa-miR-224-5p:TargetScan hsa-miR-224-5p TargetScan 4.01E-32 2.25E-28 1.00E-31 9.23E-31 79 322 "RBM10,ADCY6,ADD2,ADRA1B,HECW2,KIF6,PPFIA4,PHF12,APBA2,ATP1B3,BCL2L2,NRP2,CAST,C1orf52,CACNA2D2,QKI,PCYT1B,SEC14L5,PYGO1,KIAA0087,ARMCX2,FBXL5,DNM1,DPYSL2,HIPK3,EFNA3,MBNL2,EIF5,CEP85L,CDHR1,PSD2,FAM49B,FUT9,DOT1L,BRPF3,GPM6A,HMGCR,IGFBPL1,HES5,IL6ST,KCNH1,KLHL23,L1CAM,MYO5A,NAP1L1,NFIA,NOVA2,HCN1,OPCML,OPHN1,PDE1C,GPR173,PIK3C2A,MED1,MAPK8,GDPD1,RELN,PTX3,RASGRF2,ERI2,RPRD1A,C12orf49,PCMTD2,ACER3,CASC3,MAGI3,KDM3A,POGZ,ATP11A,ANKRD12,ARHGEF12,CYB561A3,CBX5,C9orf85,FNDC5,CADM1,DPYSL5,DHX33,KAT6A" MicroRNA hsa-miR-511-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.46E-32 2.50E-28 1.11E-31 1.03E-30 71 261 "ADD2,PTCHD1,HACE1,TAOK1,MARCH3,ATP2A2,BACH1,CALM1,SEPT7,CFL2,IGLON5,ACBD5,PPP1R16B,DCAF8,DBT,YTHDC1,DMD,CDON,MBNL2,ABI2,EIF5,EPHA5,KATNAL1,DLC1,FGF14,UBE2E3,AFF2,TRMO,FAXC,MMADHC,CBX1,NR3C1,BVES,ZDHHC15,DOCK7,IL6ST,CLVS2,KCNJ3,KLHL23,KCNQ3,KPNA5,LIFR,SMAD9,LYPLAL1,SYT9,MKLN1,MYO5A,NCAM2,NELL2,NLGN3,CCSER2,PLP1,SDK2,SPATA6,SATB1,CSRNP3,SCP2,FNIP1,KIF13A,SOX5,ZHX3,ARHGEF9,PLCB1,TRIM2,HHIP,TUB,KCNK12,ZNF138,ADAMTS9,KAT6A,SSPN" MicroRNA hsa-miR-24-2*:mirSVR_highEffct hsa-miR-24-2*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.85E-32 2.73E-28 1.21E-31 1.12E-30 82 347 "NCKAP5,CDC7,CC2D2A,SMIM17,ARHGAP20,CCDC146,ASPH,ZSCAN18,BMPR1B,BTK,CALB1,CALM1,USP2,ZMYM4,SRSF11,CLCN4,ARMC8,NRSN1,CYBB,GAPVD1,TOMM20,MAGI2,RAB39B,DTNB,EMX2,MEX3B,SGIP1,ARPP21,TUBA8,GLS,KDM2B,GRIA4,PLCD4,ADAMTS6,GUCY1B1,GYG1,HAS2,IGF1,IGSF1,KCNK2,SYT9,MOBP,MYO9A,NCAM2,VWA2,CHAMP1,OLR1,PCDH9,NXPH1,TMEM260,ENOX1,OXR1,KCNIP1,DRAXIN,HOGA1,TNFRSF19,SCAF8,SLC1A3,CPEB4,CDK5RAP2,SNRPN,PDZD2,BDP1,ENKUR,SRPK2,ATP10B,SSTR1,ERBIN,ANKRD28,TCF7L2,TCF12,DOCK9,NSD1,SLC44A1,GZF1,BHLHB9,CLHC1,PORCN,ZNF711,HNRNPA3,PHTF2,RNF170" MicroRNA hsa-miR-513c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.48E-32 3.08E-28 1.37E-31 1.26E-30 60 185 "FZD9,SPOP,ASCL1,ATP2B1,ZNF582,BACH1,NIPA1,ZNF555,MAP7,HS3ST5,HDAC4,DCC,EDN3,ENPP6,SGIP1,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,NAP1L1,SNTG1,CCSER2,KANSL1,PRKACB,UHRF1BP1,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,SRPK2,CEP68,TCF7L2,PSD3,DICER1,HHIP,TRPS1,SF1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-567:PITA hsa-miR-567:PITA_TOP PITA 5.79E-32 3.25E-28 1.44E-31 1.33E-30 57 166 "ACLY,ABHD6,ARID1A,ALCAM,EIF4G3,B3GALT2,JAZF1,WASF1,LRBA,CDC42,CTNND2,PUM1,SNAP91,DLG2,PDCD6IP,EGR3,EIF4G2,EPB41L2,PSD2,NCKAP1,GK,USP54,KCNMA1,SMAD1,MARK1,MBNL1,CHIC1,XRRA1,NEUROD1,NEUROD2,FAM98B,STRN3,LRP12,GDPD1,QRICH1,OXR1,CLIP1,SCN8A,FNIP1,HSPA4L,CCDC88A,CAMTA2,SS18,PRRC2C,ATP11A,TCF4,SYNE1,ARHGEF12,DICER1,ZBTB38,SYNC,CADM2,EVI5,KCNAB1,PHTF2,ADAMTSL3,FXR1" MicroRNA "AAGCACT,MIR-520F:MSigDB" "AAGCACT,MIR-520F:MSigDB" MSigDB 6.04E-32 3.39E-28 1.51E-31 1.39E-30 65 219 "ABR,MTUS1,OSBPL8,AK2,APP,ATP2B2,MTMR3,JAZF1,MYRF,PRC1,CDC25B,CDH2,CFL2,LETMD1,ZNF385A,CREB5,TOX,RASSF2,EDNRB,TMTC1,MBNL2,KMT5B,PAN3,EMX2,MED12L,FLT1,BACH2,IL6ST,OLFM3,KCNMA1,MEF2C,NOVA1,OCRL,OPCML,PRKACB,SLC22A23,RALGDS,ARID4A,RDX,FIGN,RFX4,RIC8B,FNDC3A,SLITRK3,WDR37,SLC6A9,TET1,IQSEC2,CDK19,LMO3,RGL1,ARHGEF9,FBXW11,ZFPM2,DDHD1,ZFP91,NR2C2,VLDLR,RICTOR,SYNC,RGMA,PRDM8,FAM13C,PAK5,VANGL2" MicroRNA hsa-miR-10a*:mirSVR_highEffct hsa-miR-10a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.33E-32 3.56E-28 1.58E-31 1.45E-30 80 332 "CLK4,FMNL2,SLITRK1,KIAA1324,LRRC7,LCORL,PPFIA1,CNTNAP1,FAM131A,API5,SGCE,CALB1,CAMK2G,KRIT1,CD38,ZMYM4,LGI1,SLC4A7,ABI3BP,HS3ST5,ABCG1,OSBPL3,CTH,DBN1,ARMCX4,ZEB2,DMD,ABCC9,E2F6,EBF1,EDNRA,YAF2,EPB41L2,GPHN,VPS26C,EYA1,ERGIC3,PHYHIPL,MEGF10,ZMYND11,RAPGEF6,LPAR4,RAPGEF4,GRIA2,KIFC3,HECTD2,MARK1,NTRK2,RC3H2,ING3,SPATA6,HYDIN,ZNF615,RADX,SETD5,EXD2,ELP2,CLIP1,MIR124-2HG,ATXN2,DOCK10,SEC31A,PPP4R3A,SLC14A1,MBD5,KDM4C,BEX1,KIF1B,ATP11A,MTCL1,WASHC4,CLASP1,NR2E1,TPD52L2,TSN,TMEFF2,PLEKHH2,RICTOR,PAK5,NETO1" MicroRNA "TCTCTCC,MIR-185:MSigDB" "TCTCTCC,MIR-185:MSigDB" MSigDB 6.41E-32 3.60E-28 1.60E-31 1.47E-30 48 114 "ARID1A,PCDH10,APP,PRX,ATP1A3,CARMIL3,ADGRB1,BSN,CAMK2D,CDC42,MAGI1,FOXN3,CPNE6,ZNF385A,PHYHIP,PITPNC1,C2CD2L,CORO2B,GAP43,KCNN3,MAT2A,NEUROD2,NTRK3,PBX1,PTPRE,RIC8B,ATAT1,LRFN5,KIF1B,NFASC,PHLDB1,SLC37A2,ASTN2,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,THRA,TJP1,SSBP2,SF1,SLC30A3,CA10,PAK5" MicroRNA hsa-miR-30b-5p:Functional MTI Functional MTI miRTarbase 6.93E-32 3.89E-28 1.72E-31 1.59E-30 90 416 "CDC7,AP2A1,TAOK1,SEMA6A,MARCH4,PCDH10,TNRC6C,USP37,ATM,STX16,ATP2A2,DPY19L3,ST3GAL5,NIPBL,SLC4A7,TBPL1,BAG4,PREPL,CREM,CSF1,MATR3,BLOC1S6,SACS,FEM1B,CELSR3,MRO,MBNL2,ASB3,DCTN4,EPB41,SCML2,CHST15,ZNF589,FOXG1,CELF1,MSANTD4,HHIPL1,GAB1,IP6K3,DBF4,TNRC6A,FERMT2,EML4,MIER3,ELOVL5,JAK1,LIFR,SMAD1,LYPLAL1,MBNL1,MTR,NAP1L1,OPHN1,CAMKV,PPP3CB,MAPK8,UHRF1BP1,REV3L,SEC61A2,RNF220,PBRM1,SETD5,ALG9,PCMTD2,ACER3,SBF1,WDR37,BTBD7,CPEB4,TRERF1,BDP1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,ELOVL4,SYPL1,SLC35G2,NACC2,HEY1,RGMB,ZMYND8,XPO1,MKRN3,ZBTB38,ZFAND5,LRP8,PHTF2,ZDHHC20" MicroRNA hsa-miR-4253:mirSVR_highEffct hsa-miR-4253:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.05E-32 3.96E-28 1.75E-31 1.62E-30 97 478 "ADARB2,KLHL32,ERMN,KIAA1211,CARNS1,LTBP4,BEGAIN,PKP4,ALS2,CADPS,STK33,ATP1A2,ATP6V1G2,CFLAR,IL33,CACNA1B,CBS,CLDN10,ARHGAP33,CASC2,PREPL,RGS6,CCDC144A,RIPOR2,ARHGAP24,SPATA2,COPS7A,G3BP2,DNM1,RPS6KL1,KMT5B,EIF4G2,CLVS1,TOMM40L,GORAB,CAP2,GAD2,FAM120B,GCK,TDRKH,GRM7,SLC2A6,FRMD5,ARHGAP36,MIER3,HNF4G,KCNA6,KCNC1,MDM4,MEIS2,CD200,FXYD6,SLCO1C1,NPTX2,NTRK2,NTRK3,PCMT1,PDYN,POLR2F,PPP3CB,CEP41,HYDIN,APTX,MDGA2,PEX5,LGI2,C12orf49,ATP8B4,CSRNP3,AMBRA1,ZNF365,SLC4A3,PEX26,ZSWIM8,UHRF1BP1L,MYCBP2,KDM4C,ZC3H13,ZBTB43,NKAIN2,NUDT10,TACC1,ANO4,SATB2,TIE1,ASXL3,C5orf64,RASD2,TPM2,SMUG1,UBE2H,UGT8,XPO1,ZIC2,ZIC3,TRAM2-AS1,KLHDC1" MicroRNA hsa-miR-4419a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.42E-32 4.17E-28 1.84E-31 1.70E-30 76 301 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-6130:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.42E-32 4.17E-28 1.84E-31 1.70E-30 76 301 "DPF1,ELFN2,RNF157,ADD2,HACE1,SORCS2,AK2,PPFIA3,FOXK1,DDR1,HAP1,FMNL3,ARHGEF6,ZNF385A,NCOR2,PITPNM3,KIAA0513,IST1,IP6K1,SEC16A,CHRDL1,EN2,EPB41L1,FGFR1,GFRA1,GLYR1,STARD3,GSN,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,NBL1,ZC3H12B,NDUFA5,NFIX,NOVA2,TBC1D25,OGDH,PDE4A,GPR173,CDK14,POLR2F,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,MYH14,KIAA0895L,HES6,CLSTN1,RPH3A,CCDC88A,TRIM67,SLC11A1,SP2,IQSEC2,SMOC1,STX1A,ADAMTS17,ASTN2,HHIP,KCTD2,TPM2,TPM3,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF70,SIGLEC10,NAV2,PARP11,ACTR3B" MicroRNA hsa-miR-890:PITA hsa-miR-890:PITA_TOP PITA 7.52E-32 4.22E-28 1.87E-31 1.72E-30 68 241 "RALGAPA1,ESYT2,ANK1,AQP4,ARHGAP5,NCOA1,CALM1,FOXN3,LHX2,NRXN3,SLC35F1,MATR3,PITPNC1,MYEF2,ELMO1,ALKBH8,FAM107B,CPEB2,EFNB3,CELSR3,PLEKHA1,EPB41L2,KATNAL1,CLVS1,ZIC4,GAD2,AHCYL1,B4GALNT1,GAP43,AHDC1,GK,EML4,PCLO,BACH2,MIER3,IDH3A,L1CAM,MBNL1,MN1,MYCN,MYO6,MYT1,ZC3H12B,OPCML,PDE1B,PIK3R1,PURG,MINDY2,PPP2R5C,PTPRB,PTPRD,FAM120C,TRA2B,MAGI3,CHD9,DOK5,RBM26,RGL1,ANKRD28,FBXW11,RBFOX2,TRPS1,OSBP2,NSD2,CELF4,POLR3H,VANGL2,SOCS4" MicroRNA hsa-miR-1539:mirSVR_lowEffct hsa-miR-1539:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.77E-32 4.36E-28 1.93E-31 1.78E-30 85 374 "CDC7,FAHD2CP,CDC42BPA,ANK1,SUGT1P4-STRA6LP-CCDC180,ZFYVE28,ADAM23,ADAM15,DDR1,CDH18,DGCR9,CNRIP1,NCOR2,MICAL2,CCDC144A,TBC1D5,NTM,DMTF1,SYT15,ENO2,WAC,PPP1R1B,IP6K2,NELFCD,RASL10A,NEURL4,STAG2,HRASLS5,GABRB1,FAM120B,GCK,GFAP,GGT5,ZNF638,KCNMB4,GNAS,ADAMTS13,GRIK5,NR3C1,ZBTB45,LINC01551,HMGB1,DISP2,KCNK1,GPR155,MDM4,PPM1L,CTNNA3,MXI1,NNAT,DNHD1,PCBP3,PDGFRA,SEMA5B,PNMA3,SCHIP1,PRKAB2,PRKCG,ZCWPW1,RIC8B,ARMC5,PRCD,SH3BP2,SHMT2,RADIL,SLC8A3,ARFGAP1,UNC80,WDTC1,STAU1,TCF7,PHF24,FAM189A1,CHST5,ZNF346,NTSR2,RUSC1,TSC1,AMOT,LAT2,SLC26A10,SEMA3B,PDSS2,HNRNPA3,NUP214" MicroRNA hsa-miR-4753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.92E-32 4.45E-28 1.96E-31 1.81E-30 78 317 "AS3MT,FAM43B,NLGN4X,MTA3,TAOK1,CDC42BPA,PARG,DGKD,USP37,ASCL1,GPR146,PROM1,CAMK2G,SPAG9,CD86,PNKD,RIMS4,CST3,PITPNM3,ZSCAN23,GAPVD1,RIMS3,MAML1,ZC3H11A,RCAN1,SH3GLB1,ABI2,ELAVL3,RGS17,EMX2,NRN1,FGF1,CELF1,GALR1,WASF3,SULT1C4,GFRA1,PTPRT,NEGR1,IGF1,ZIC5,IL6R,KCNK2,GPR155,CD200,MYBPC1,NOVA2,NPTX1,P2RX7,PDE3A,GDAP1L1,PLCL1,PLP1,PPARA,KANSL1,PRKCB,PTPRN2,ZSCAN2,FIGN,TMLHE,CSRNP3,ATXN1,ATXN7,SGK1,IGSF9B,RBM26,ANKRD28,EXOC7,TGFBR3,HHIP,FBXL16,TNS1,FAM181B,ZBTB38,ZNF195,CADM2,NAV2,CBLN2" MicroRNA hsa-miR-4306:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.24E-32 5.19E-28 2.29E-31 2.11E-30 69 249 "DPF1,ARID1A,ADD2,CASKIN1,HACE1,TAOK1,PDZD4,KIF6,SFMBT2,IGDCC4,BACH1,EPS15L1,ARHGEF6,ZNF385A,CSF1,MICAL2,CSNK1E,CNTNAP2,SLITRK5,TM9SF4,IP6K1,SPATA2,ZC3H11A,CHRDL1,ABCC5,E2F6,ELAVL3,FGFR1,AMOTL2,AFF2,CELF1,SRCAP,TNRC6A,RAPGEF1,KAT7,SLC6A17,ZFYVE27,C10orf105,PABPC1L2A,ZC3H12B,NEUROD1,GPR137C,PDE4A,PFKFB3,CDK14,PKD1,PKM,PLCD1,PTPA,RAB5B,PRRT2,MORC4,MYH14,HSD11B1L,MRAS,BTBD3,PKNOX2,CCDC88A,WDTC1,IQSEC2,AHCYL2,HHIP,TMEM9,TMPRSS5,CADM1,SF1,SLC38A1,SIGLEC10,ITM2C" MicroRNA hsa-miR-645:mirSVR_highEffct hsa-miR-645:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.52E-32 5.35E-28 2.36E-31 2.17E-30 89 409 "KCNH8,TKTL1,PLEKHH1,PTCHD1,ZNF578,ALS2,SFMBT2,DACT3,DPY19L3,NRP2,ARHGEF7,IL33,PTBP2,RUNX1T1,MTMR7,TMEM257,SYNGR3,AP4M1,LRBA,CDH18,IQCK,ARMC8,ZNF521,CP,CREM,PUM1,HDAC9,GIT2,KIAA0319,DLG2,DMD,DNAH9,DYRK1A,SUGP2,RASA4,PAN3,SRRM1,NSRP1,FCGR1A,PHYHIPL,GABRG2,NEK6,NCKAP1,PCDH11X,DCLK2,WDFY3-AS2,HPSE2,LIX1,INPP5B,LRRTM3,KCNK2,KCNN1,MITF,AFDN,MTR,NF1,ODF2,BEST3,SH3KBP1,PPP3CB,MDGA2,ZSCAN32,ZDHHC4,ROBO1,PCMTD2,ACER3,RXRG,DOCK10,ANKRD6,SEPHS1,SLC8A1,SLC15A2,SCMH1,CLUAP1,HECW1,UNC5B,KLHL7,C12orf76,TCF12,CLASP1,FAM200B,TLL2,XPO1,ZBTB38,WNK1,CADM2,STMN4,WIPF2,PARP11" MicroRNA "CACCAGC,MIR-138:MSigDB" "CACCAGC,MIR-138:MSigDB" MSigDB 9.74E-32 5.47E-28 2.41E-31 2.22E-30 62 200 "UNC5A,ANK1,NCOA1,CASTOR3,JAZF1,CACNA1E,CBFA2T2,CNOT8,ZNF385A,SLC35F1,OSBPL3,HDAC4,RIMS3,MYEF2,NTM,CALN1,DSCAM,DNAJB6,EFNB3,KMT5B,RCAN2,CLVS1,BAIAP2,NBEA,ZMYND11,SRRM4,PPARGC1A,GLI2,FERMT2,CIT,KCNMA1,MOV10,MSI1,NFIX,NPTX1,PCSK2,PDE3A,EPB41L4B,VSTM2L,RELN,PTK2,USP47,ST3GAL3,SLC6A8,KBTBD4,CPEB4,SNCB,SPTB,IQSEC2,UNC5D,ADGRL3,KIAA0930,AHCYL2,SIRT1,TPM4,TRPS1,MGAT5B,MEAF6,SLC17A7,KAT6A,ADAMTSL3,JMJD1C" MicroRNA hsa-miR-425:PITA hsa-miR-425:PITA_TOP PITA 9.74E-32 5.47E-28 2.41E-31 2.22E-30 62 200 "ZNF608,KLHL13,AMPH,ANK3,CANX,CFL2,SRSF11,FOXN3,NMT2,ARMC8,WHRN,AKAP5,MYRIP,SEC24C,CTNND1,MAML1,DGKG,ELMSAN1,CPEB2,DYRK1A,GOLT1B,FAM135B,DNAJC27,ATP8A1,AFF2,DKK3,CAB39,CPLX2,PCLO,HLF,ELOVL5,IGF1,ITPKB,KCND1,IPO5,STMN1,LRP1B,MEF2C,GIT1,MYO5A,CNOT4,OCRL,PCMT1,MINDY2,PTCH1,PTPRN2,FIGN,CHD9,PPP4R3A,EPN2,SLC6A1,SNAP25,PDZRN3,TEX2,ZNF423,PRRC2C,SYN2,ATP11A,RPGRIP1L,DICER1,TMEM237,KAT6A" MicroRNA hsa-miR-424-5p:Functional MTI Functional MTI miRTarbase 1.01E-31 5.66E-28 2.49E-31 2.30E-30 96 471 "AXIN2,FZD9,ADORA3,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,APBB2,APP,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,FOXK1,CA8,CANX,RUNX1T1,CCNT1,SOCS6,DLGAP3,CLU,MAGED1,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,SACS,DMPK,DMTF1,FCF1,HEYL,SIDT2,EIF4G2,PLEKHA1,EN2,ZNF391,ANKMY1,ZNF585B,FGFR1,CAMSAP1,MSANTD4,NCKAP1,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,ARHGAP12,CHIC1,CCDC80,MYO5A,NFIA,OCRL,PDE4D,ANLN,PIK3R1,PSAT1,PPP2R5C,PTCH1,ANKHD1,PTPRD,PLEKHB2,RBBP6,ZFHX4,TMEM100,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,ZMAT3,TGFBR3,TPM2,TPM3,TUBB2A,UBE2H,AMOT,VAV2,ZBTB16,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-513a-3p:Functional MTI Functional MTI miRTarbase 1.08E-31 6.06E-28 2.67E-31 2.46E-30 60 187 "FZD9,SPOP,ASCL1,ATP2B1,ZNF582,BACH1,NIPA1,ZNF555,MAP7,HS3ST5,HDAC4,DCC,EDN3,ENPP6,SGIP1,TMEM107,PDLIM5,FYB1,GALC,TPPP,NEGR1,CREG2,KIF5A,LOH12CR2,LIMS1,MBNL1,CHIC1,SRSF12,NACA,NAP1L1,SNTG1,CCSER2,KANSL1,PRKACB,UHRF1BP1,PTPRB,ZMAT4,GTDC1,SETD5,ALG9,RORB,ATP8B4,ZFP30,CPEB3,SLC8A1,PEG10,SRPK2,CEP68,TCF7L2,PSD3,DICER1,HHIP,TRPS1,SF1,ATP6V0E2,ZXDA,CADM2,PRDM10,KCNAB1,JMJD1C" MicroRNA hsa-miR-31*:mirSVR_highEffct hsa-miR-31*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.10E-31 6.16E-28 2.71E-31 2.50E-30 83 359 "RALGAPA1,AS3MT,KIAA1324,VAT1L,LINC00173,MARK4,RIPK1,BACH1,CA8,CA12,KALRN,RUNX1T1,SYNGR3,LRRFIP1,CHN2,CHRM1,ARHGEF10,PLXNA4,PNPLA8,KIF26A,DAPK1,USP3,DLC1,FCGR3A,NSG2,ZNF512,NCKAP1,WASF3,RND1,TCERG1,PCLO,FAM19A2,MAP4K5,GPR62,SMAD1,TM6SF1,LRP1B,MN1,MOV10,ERICH3,MSR1,NFE2L2,GPR88,GPR137C,GNG2,BEST3,PLCL1,EPB41L4B,RAB39A,MASP1,SNRK,ARID4A,GTDC1,RGS7,ADAL,ZNF568,CCDC112,CSRNP3,FNIP1,SH3BGR,ITSN1,SH3GL2,SYBU,SEC31A,SLC6A11,NAPB,DBNDD2,EPB41L3,SSPO,VPS13A,PLCB1,COBL,TCEA1,EHBP1,CRB1,TRPC1,CADM1,UBE2H,UGT8,PCDH20,ZNF711,EMSY,WIPF2" MicroRNA hsa-miR-136:PITA hsa-miR-136:PITA_TOP PITA 1.10E-31 6.19E-28 2.73E-31 2.51E-30 70 257 "SYN3,PWWP2A,MAP4K3,APAF1,CACHD1,USP37,CDC14B,ZFYVE28,ZBTB10,JAZF1,BTRC,KALRN,CAMK2G,CCPG1,CACNA2D2,FOXN3,KMT2C,AKAP5,SLC4A7,SH2B1,RIMS2,CPEB2,APH1A,MBNL2,COPS4,EYA1,MEGF10,SRRM4,GATM,PPARGC1A,TNRC6A,GNG3,GRID1,MIER3,HPCA,ITGAV,KCND1,HS6ST3,NEXMIF,NCAM1,ZC3H12B,NOVA1,PIK3R1,PLP1,STRN3,POU3F2,MINDY2,SNRK,TMEM260,PTPN13,PTPRG,ARID4A,RET,RGS4,RORB,RYR3,LRRTM4,ITSN1,PPP4R3A,CPEB4,RCOR3,NECAB1,ADGRL3,EHBP1,RPGRIP1L,PSD3,VLDLR,ZIC3,SYNC,PRDM8" MicroRNA hsa-miR-485-5p:PITA hsa-miR-485-5p:PITA_TOP PITA 1.22E-31 6.87E-28 3.02E-31 2.78E-30 61 194 "SDE2,TAOK1,LRRC7,OGT,CNIH2,CNTNAP1,SEMA4G,ATP2B2,BSN,MAGI1,QKI,CNTFR,CREB5,FEZ1,ATRNL1,YTHDC1,RUSC2,TMCC2,DPH1,DRP2,PHC2,ELN,EPB41L2,NBEA,GABRB3,PPARGC1A,RND1,GRIN1,RNF165,IBA57,KCNA1,KLC1,CAMK2N2,MDGA1,MYT1,NNAT,NOVA1,NRGN,NTRK3,PDE1B,PLEC,PMP22,MED1,PSD,RNF220,RIC8B,ZFHX4,KIRREL1,CHD9,FAM214B,SOX5,LHFPL4,SYT11,SZT2,ZFP91,ZNF384,SF1,REEP1,CADM2,SNX27,WNK3" MicroRNA hsa-miR-4768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-31 7.92E-28 3.48E-31 3.21E-30 115 653 "SDE2,ARID1A,NDRG3,SLC24A4,TXNDC16,SMIM17,TRMT9B,APAF1,AQP6,CDC14B,SFMBT2,PDXK,ARHGDIA,ASPA,ATM,ZNF583,BTRC,ZNF555,PTBP2,ISPD,CBS,MTMR7,SLC16A4,MYOM2,CCPG1,GPR37L1,NDST3,NRXN3,MFSD4A,SLC35F1,SUSD5,IPCEF1,PITPNM3,CTH,RUBCN,USP6NL,PYGO1,KIAA0513,RASSF2,LONRF1,TMEM170A,ELMSAN1,PLEKHM1,SLC29A4,GNE,SYT15,HEYL,ZNF549,VPS26C,ZNF585B,ZNF589,ATP13A4,KBTBD12,MSANTD4,MTHFD2,GJB1,GPR75,GLUL,ZNF638,LUZP2,GNAS,GNG3,LILRA2,KIF3A,ZBTB49,BVES,AGBL5,KCNH2,KCNJ5,KLHL23,STMN1,SMAD9,CHST6,PPM1L,MMP17,MPP2,MXI1,SFR1,NUCB1,ZNF713,PIK3CD,PLEC,FTO,PACSIN1,PTPA,KANSL1,MTMR10,ZNF844,QDPR,CEP97,ALG9,GSTCD,SNX22,HSD11B1L,IL17RB,PREX2,SLC2A5,CDK19,NEK4,FAM168A,FAM208A,SLC19A3,PSD3,PCDHA6,AHCYL2,TMEM9,TPM3,SSBP2,LRTM2,ZNF610,RPRM,TBC1D15,DNALI1,SNX27,MPPE1" MicroRNA hsa-miR-2114*:mirSVR_highEffct hsa-miR-2114*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.57E-31 8.82E-28 3.88E-31 3.57E-30 91 429 "AXIN2,SORCS1,ZNF578,DPP10,BCAS1,NUMB,ATP2A2,NOL4,BCL7A,CARS,P2RX6,CBFA2T2,CD38,LARGE1,DIS3L,CHRNA4,FAM171B,CS,NCAN,ECE2,DOCK4,ARMCX4,PITPNC1,MYEF2,COPS7A,POM121,DLX1,GRIN3A,HS3ST2,ECM2,APH1A,EGFR,IRAK4,FCGR1A,TBR1,NRG3,MEGF11,GABRA2,RAPGEF6,TMEM8B,GFAP,TNRC6A,TDRKH,LILRA2,ZNF496,ZBTB49,MAEL,MIER3,HMGB1,CELF5,MYLK2,KCNK2,KCNMA1,KCNN2,KLC1,MEF2C,MOBP,RTL5,NDP,NUCB2,PCSK2,CDK18,PLP1,HYDIN,MASP1,APTX,GON4L,QRICH1,ATG16L1,PBRM1,RNASEL,CARF,ATAT1,FAM19A1,CTXN2,ABLIM3,SLC1A3,SLC1A7,ELMO2,LIMCH1,KDM4B,ZSCAN29,VAMP1,PCDHGA11,HEY2,TPM1,TRO,KCNE5,OSBP2,RICTOR,AMN1" MicroRNA hsa-miR-4644:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-31 8.94E-28 3.93E-31 3.62E-30 69 251 "DPF1,ARID1A,ADD2,CASKIN1,HACE1,TAOK1,PDZD4,KIF6,SFMBT2,IGDCC4,BACH1,EPS15L1,ARHGEF6,ZNF385A,CSF1,MICAL2,CSNK1E,CNTNAP2,SLITRK5,TM9SF4,IP6K1,SPATA2,ZC3H11A,CHRDL1,ABCC5,E2F6,ELAVL3,FGFR1,AMOTL2,AFF2,CELF1,SRCAP,TNRC6A,DCLK2,RAPGEF1,SLC6A17,ZFYVE27,C10orf105,PABPC1L2A,ZC3H12B,NEUROD1,GPR137C,PDE4A,PFKFB3,CDK14,PKD1,PKM,PLCD1,PTPA,RAB5B,PRRT2,MORC4,MYH14,HSD11B1L,MRAS,BTBD3,PKNOX2,CCDC88A,WDTC1,IQSEC2,AHCYL2,HHIP,TMEM9,TMPRSS5,CADM1,SF1,SLC38A1,SIGLEC10,ITM2C" MicroRNA hsa-miR-339-3p:mirSVR_lowEffct hsa-miR-339-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-31 9.05E-28 3.98E-31 3.66E-30 86 386 "DGCR6,UNC5A,PCDH19,AMPD3,SUGT1P4-STRA6LP-CCDC180,CPNE5,SLC2A11,N4BP2L1,ADAM15,CA4,THSD7A,PTBP2,CBFA2T2,TAOK2,ARHGAP22,SULT4A1,PICK1,LETMD1,RTTN,MFSD4A,CREM,SNCAIP,CST3,PITPNM3,CTNND2,TOMM20,ZEB2,USP3,TOM1,DUSP9,EPHB1,RACK1,SLC37A3,ARFGAP2,SALL3,RUNDC3A,MSL3,ZNF638,GRM7,CLASRP,FAM222A,VSIG4,ITGA7,KCNMA1,CTNNA3,NCAM1,NUMA1,PFKFB3,PPP1R1A,PRKCZ,DIRAS2,NDUFS7,WBP1L,TMEM260,FAM66C,RBBP8,ERI2,RGS12,RPRD1A,ZNF532,YJEFN3,FAM192A,PAAF1,SLC6A9,SLC14A1,ARFGAP1,TTC17,WDTC1,ZNF423,PBLD,AGTPBP1,MGRN1,PCDHGA11,TMEM151B,GPRIN3,HEY2,DAAM2,RIMBP2,TRIO,CLEC2L,TOM1L2,VIPR2,CLIP2,URM1,FIP1L1,SLC4A10" MicroRNA hsa-miR-377-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.66E-31 9.33E-28 4.10E-31 3.77E-30 71 266 "ARID1A,TMEM132B,ADCYAP1R1,INTS2,KCTD16,GOLGA7B,CADPS,ATM,ALDH7A1,CADM3,JAZF1,CACNA1B,CRLF1,STOML1,CLTC,NRG2,NCAN,CENPL,EDIL3,SNX29,EGR3,SLC43A2,HSPA12B,FOXF2,NBEA,SPECC1,MSANTD4,SESN1,EML4,TPPP,GRID1,NR3C1,FRMD3,HLF,USP51,C2orf72,TJAP1,IBA57,KCNA4,KCNK1,LAMP2,ARHGAP12,FXYD6,ZDHHC22,PDE3A,PFKFB2,DUSP26,PKD1,PROX1,APTX,ZYG11B,ROBO1,HUNK,SCN8A,CPEB3,RAB3GAP1,CPEB4,PDZD2,TRERF1,MYCBP2,SEPT3,SYT5,TAL1,BHLHB9,KCTD2,ZNF610,UBE2H,ZNF781,CRB2,ZNF195,LRP8" MicroRNA hsa-miR-1203:mirSVR_lowEffct hsa-miR-1203:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.78E-31 9.98E-28 4.38E-31 4.03E-30 82 353 "TTYH1,ASIC2,SUGT1P4-STRA6LP-CCDC180,PKP4,PPFIA3,SLC2A11,TTLL9,ARHGEF7,CA4,KALRN,CANX,IGFN1,CHI3L2,ZNF385A,CTNND2,RUBCN,EARS2,DOCK2,FAM57B,RCAN1,USH1C,EDN3,HIPK3,EBI3,ANKRD13B,SLC43A2,SRRM1,POLR1B,CAP2,AGAP3,SEMA4D,WDR83,APOPT1,CGREF1,DOT1L,ZNF274,TUBA8,ADGRA3,CCDC184,TMEM25,ZBTB49,CELF3,ARHGAP19,C2orf72,LRRTM3,KCND1,LAMP2,PACRG,MYO7A,CCDC13,PAX6,GNG2,PURG,PMP22,SDK2,DEF8,RALGDS,ZNF331,MAPK12,HOGA1,SEC14L1,SOX6,NAXD,SLN,RIMS1,WDTC1,SMOC1,AJAP1,MGRN1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,RUSC1,LRP8,LINC00632,FBXO36,CASC15,JPH3" MicroRNA hsa-miR-1275:PITA hsa-miR-1275:PITA_TOP PITA 1.92E-31 1.08E-27 4.72E-31 4.35E-30 51 133 "KCNH8,ARID1A,NDRG3,HECW2,PCDH19,CNTNAP1,SEMA4G,ARNTL,NCOA1,JAZF1,CACNA1A,CACNA2D2,NRXN3,NRXN2,SH2B1,SLC12A6,DPP6,DUSP9,DYRK1A,PHC2,EFNA3,ELAVL3,ANKRD13B,AGAP2,DCTN2,ATF7,GRIN1,CELF3,ATXN2L,IGF1,INSYN2,GIT1,NEUROD2,NFIX,PDE1B,POU3F2,MED1,SETD5,PKNOX2,SLC11A1,CPEB4,SMARCC2,ANKRD28,MTCL1,EHBP1,FBXL16,RIMBP2,TRPS1,SMARCAD1,CA10,URM1" MicroRNA hsa-miR-6749-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-31 1.11E-27 4.85E-31 4.47E-30 86 387 "FAM43B,ADD1,SLC12A5,GRAMD1B,RNF150,SEMA4G,PRX,ATP2B1,ATP2B3,CASTOR3,NIPA1,CA8,CAMK2G,CDH8,SLC22A6,STOML1,RTTN,TENM4,LRIG1,UBXN2A,PLCXD3,RIPOR2,FRMPD4,KIF26A,RUSC2,KIAA0319,TMCC2,EXOG,RCAN1,TMTC1,SLC43A2,TMEM132C,FER,IP6K2,UFM1,GABRG2,GBX2,POLL,GRID1,GRIK3,ADAMTS13,FAM107A,GPR45,BACH2,HMGB1,TLX1,SHISA6,NKD1,KCNJ4,KCNJ11,LSAMP,MAT2A,MID1,MYO5A,NODAL,DDR2,PKD1,PNMA3,TNPO2,PTAFR,NCR3LG1,RAB5B,GSTCD,HSD11B1L,SLIT1,SMARCE1,PALLD,ZHX3,CLUAP1,NSFL1C,TMEM178B,EXOC7,NSD1,ZMAT3,THRA,NACC2,TMPRSS5,GORASP1,ZBTB16,TMEM198,SLC30A3,PMEPA1,SIGLEC10,FAM13C,GAN,JPH3" MicroRNA hsa-miR-6809-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-31 1.11E-27 4.88E-31 4.50E-30 78 321 "FAM43B,RNF157,NLGN4X,MTA3,MARCH4,PARG,DGKD,USP37,ASCL1,PTCH2,GPR146,CAMK2G,CD86,CDH8,RAB3C,PNKD,CST3,PITPNM3,ZSCAN23,GAPVD1,MAML1,C2CD2L,CDON,EDN3,SH3GLB1,ABI2,ELAVL3,RGS17,EMX2,TUBB4A,CELF1,GABRA1,GALC,WASF3,GATM,SULT1C4,GFRA1,GPR26,PTPRT,TLX1,NEGR1,IL6R,KCNK2,GPR155,MYBPC1,NFIX,NOVA2,NPTX1,P2RX7,GDAP1L1,PLCL1,PKIA,PRKCB,SNRK,PTPRN2,ZSCAN2,FIGN,TMLHE,CSRNP3,ATXN1,SGK1,CPEB3,CHD9,ZNF667,IGSF9B,ZNF415,RBM26,TROVE2,HHIP,FBXL16,TNS1,SGK3,ZNF23,DHX33,CADM2,PRDM10,NAV2,MPPE1" MicroRNA hsa-miR-154:PITA hsa-miR-154:PITA_TOP PITA 2.34E-31 1.31E-27 5.75E-31 5.29E-30 61 196 "USP31,INTS2,MTUS1,OSBPL8,ANK3,LCORL,TMEM108,ATP2B1,CAMK2G,FOXN3,NRXN3,SLC35F1,SOCS5,MAGI2,ABI1,DYRK1A,E2F5,RBM12,RTN3,WAC,GABRG2,B4GALNT1,SRRM4,GATM,LUZP2,STON1,GRM7,KAT7,NEGR1,SOWAHA,C5orf24,MEF2C,NAP1L1,NFIA,CNOT4,NTRK2,PRRX1,MED1,MINDY2,GDPD1,RAB5B,TMEM255A,ARID4A,GTDC1,SALL1,FNIP1,PPM1E,CPEB3,SLC1A2,PPP4R3A,PKNOX2,SP4,SYT4,CUX2,TCF12,FBXL16,TIAM1,CLDND1,CADM2,EVI5,FXR1" MicroRNA hsa-miR-6890-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-31 1.37E-27 6.02E-31 5.54E-30 95 467 "CLK4,XKR4,ADCY5,MTA3,PHF12,CDC14B,KIAA1614,PRX,INSYN2B,SLC2A11,BMP7,FOXK1,CFAP410,DIRAS1,CAMK2G,MAP7,DIS3L,RTTN,RNF14,HINFP,OSBPL3,UBXN2A,FGFR1OP2,ZBTB24,SLC12A6,KRBA2,IRAK4,MRNIP,RGS17,TUBD1,PLEKHO1,SLC43A2,IGSF6,SRARP,TESK2,FGFR1,SEC23B,PCYOX1,APOPT1,PDLIM5,MSANTD4,NCKAP1,MYOZ2,DBF4,GLUL,KDM2B,RAB40B,LILRA2,RFFL,DDX19B,HMGB1,SCRG1,ZNF546,NKD1,IL6R,IBA57,CYP27C1,LIMS1,ARHGAP12,GPR155,MOG,SAMD5,ZDHHC8,ZNF655,A2ML1,STRN3,EXOSC10,FITM2,APTX,MTMR10,OCIAD1,NWD1,PGBD4,UEVLD,DRAXIN,PEX26,ZNF430,ATF7IP,SMARCC2,BDP1,ZNF621,INKA2,KLHL7,ALG1,WWC1,ACSL6,TPCN2,PCDHA6,ZNF106,ARL10,ERCC6L2,ZNF384,FNDC5,LINC00632,FXR1" MicroRNA hsa-miR-409-3p:TargetScan hsa-miR-409-3p TargetScan 2.58E-31 1.45E-27 6.34E-31 5.84E-30 66 231 "CLK4,KIAA1211,KCTD16,C1QTNF1,FAM135A,AQP4,NRP2,MMD2,CALM1,MAP7,MTMR7,AIFM1,CFL2,LHX2,FHL5,PYGO1,MATR3,KIAA0087,DPP6,RBM12,GPR61,ABI2,EGR3,PLXNC1,ETV1,MED12L,IQCG,ANKFY1,GAB1,SALL3,PCDH17,GHR,GNAL,LNX1,NUDT21,RAPGEF4,KLF12,BACH2,HNRNPK,PLD5,KCNH1,LIMS1,MAPT,MDM4,NFIX,GPR85,GPSM2,FAM216A,SCHIP1,NXPH1,KANSL1,CEP41,RAB39A,PTPRG,RDX,DPF2,RORB,BTBD7,SCN3B,FAM168A,NECAB1,MFF,PARP6,MSRB3,FXR1,CPNE4" MicroRNA hsa-miR-1281:mirSVR_lowEffct hsa-miR-1281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.66E-31 1.49E-27 6.52E-31 6.01E-30 111 618 "SYN3,ACADM,KIDINS220,MAP4K3,MYH7B,APBA2,RGS20,ASGR1,MARK4,TMEM108,ADGRB1,RGS11,KSR1,DST,CASTOR3,TRIM41,VXN,CDC42,EVI5L,CCPG1,CASC2,JAM2,PPT2,FADS2,SLC25A27,SUMF2,MFSD4A,CSF3R,ATRNL1,RUBCN,ZFYVE16,INTS1,RUSC2,RHOBTB1,DLG2,DNM1,DMPK,PHF20L1,TUBD1,IGSF6,SPEG,CEP78,FKTN,APOPT1,PDLIM5,CSPG5,GAD1,GGT5,ZNF276,TNRC6A,GNAO1,GNAS,GP1BB,GRIA2,SERP2,RNF165,C2orf72,KIAA1755,SCIN,SCRT2,SLC6A17,LINC00634,KLC1,SFXN5,MAOB,ADAM11,CD200,NCAM2,SMIM11A,P2RX7,PCSK5,A2ML1,ANKRD16,GON4L,ZYG11B,ERI2,RFX3,RFX4,ST6GALNAC6,ASIC4,TRIM46,SLA,SLC1A7,CDK5RAP2,ANKRD36,UNC80,KIF21B,ZNF423,TSPYL2,STAU1,DIP2A,SYNE2,ARHGEF9,FNDC9,SYP,EXOC7,ANO4,SYNE1,AKNA,TIAM1,PIK3R5,NPL,C9orf85,CHST5,RUSC1,RPRM,NPDC1,TRIM9,FIP1L1,IFT88,JPH3" MicroRNA hsa-miR-135b*:mirSVR_highEffct hsa-miR-135b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-31 1.59E-27 6.96E-31 6.41E-30 92 441 "KCNH8,ADD2,ERMN,CC2D2A,ALCAM,ANK2,KCNAB2,CDK10,PPP4R4,DACT3,CA12,CAMK2B,USP2,INA,CDC27,FADS2,ABCG2,CNRIP1,NCOR1,MYEF2,FBXL5,PLPPR4,RAB39B,CPEB2,DPYSL2,FCF1,RASGRP1,EMX2,EPHB1,IGSF6,DNAJC27,SIRPB1,SUCO,GABRA2,GLYR1,MAP7D2,OS9,WDFY3-AS2,STMN2,GRIK1,COQ10A,SMAP1,MSL1,ZNF546,LIX1,KCND1,LIMS1,ARHGAP12,SMAD9,SYT9,ZNF680,NAP1L1,P2RY13,NPTX2,DDR2,PFKFB4,HMGCLL1,PURG,C19orf57,BDNF-AS,MARCH1,ZNF493,PBRM1,CCDC82,ROBO1,CSRNP3,LRFN5,FAM19A1,COPZ1,KIF16B,ZNF365,CCDC88A,SMARCD3,PDZRN3,NMNAT2,NEK4,KANK1,CAMTA1,CNTN2,WASHC4,TEK,ITGB3BP,ZNF610,PLEKHH2,ZIC3,ZNF708,ZNF28,ZNF138,PARP11,HNRNPA3,CASC15,ADAMTS10" MicroRNA hsa-miR-30e-5p:Functional MTI Functional MTI miRTarbase 2.87E-31 1.61E-27 7.04E-31 6.49E-30 81 347 "CDC7,TAOK1,SEMA6A,MARCH4,PCDH10,USP37,MIER1,ATM,STX16,ATP2A2,DPY19L3,ST3GAL5,CANX,SOCS6,SLC4A7,TBPL1,BAG4,PREPL,CREM,ZEB2,SACS,TRAPPC9,CELSR3,MRO,MBNL2,ASB3,DCTN4,VPS13B,EPB41,SCML2,CHST15,FOXG1,CELF1,MSANTD4,HHIPL1,GAB1,IP6K3,MTHFD2,DBF4,TNRC6A,EML4,MIER3,ELOVL5,HSP90AA1,JAK1,LIFR,LYPLAL1,MBNL1,MTTP,MTR,NAP1L1,OPHN1,PPP3CB,MAPK8,PSMA6,UHRF1BP1,MSANTD2,REV3L,SEC61A2,RNF220,PBRM1,SETD5,ALG9,PCMTD2,SBF1,BTBD7,CPEB4,LIMCH1,KDM3A,SP4,PEG10,STAU1,ZSCAN29,SLC35G2,NACC2,ZMYND8,XPO1,MKRN3,ZFAND5,PHTF2,ZDHHC20" MicroRNA hsa-miR-521:mirSVR_lowEffct hsa-miR-521:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.90E-31 1.63E-27 7.12E-31 6.56E-30 84 372 "PLEKHG5,AXIN2,USP31,ZFAT,INSYN2B,TTLL9,DDR1,CAMK2D,TMEM59L,AKAP6,SMARCAL1,ENTPD4,CRMP1,HAPLN1,SLC32A1,SNCAIP,OSBPL3,NRSN1,USP6NL,ARHGAP24,DAPK1,SPOCK2,LYPD1,KBTBD11,DLG3,DPP6,ECM2,SIDT2,MRPL37,GTF2IRD2,FGF13,PDLIM5,FAM49B,NPTN,CELF1,FYB1,CAB39,GHR,GLI2,KIAA1958,GNAS,PLPP7,AP4S1,SLC2A6,TMEM179,DDX19B,HMGCL,AGBL5,TLX1,IRF8,IL6ST,INSYN2,MID1,MOBP,MYO6,NEFH,NUCB2,A2ML1,NLE1,PACSIN1,POU6F1,ELOVL2,ZIK1,PTPRD,PTPRE,CASTOR1,PPP4R3A,BTBD3,SLC12A2,UNC80,RBM34,CLSTN2,PDLIM2,ACSL6,TCF4,VWCE,METTL3,UGT8,POLR3H,MEIS3,PRDM2,MVB12B,CASC15,TRAM2-AS1" MicroRNA hsa-miR-146b-5p:PITA hsa-miR-146b-5p:PITA_TOP PITA 3.53E-31 1.98E-27 8.64E-31 7.96E-30 57 171 "ESYT2,GPR158,AMPH,CASK,MARK4,NUMB,SYNJ1,JAZF1,RUNX1T1,CCK,DLGAP2,DLGAP1,RCHY1,APPL1,TOX,USP3,ABCC5,EIF4G2,ERBB4,SCML2,SARAF,TDRKH,EML4,PCLO,GRID1,CELF3,KLF12,LRRTM3,KCNMA1,MAPT,MARK1,SESN3,MYO5A,ZC3H12B,NOVA1,KCTD15,MED1,TMEM255A,USP47,RIC8B,ZNF532,SNX22,WDR47,SCN3B,PEG10,NPAS3,CLASP2,SYT1,RPGRIP1L,FRYL,HEY2,CADM1,ZIC1,TRIM9,POLR3H,CADM2,PCBP4" MicroRNA hsa-miR-146a:PITA hsa-miR-146a:PITA_TOP PITA 3.53E-31 1.98E-27 8.64E-31 7.96E-30 57 171 "ESYT2,GPR158,AMPH,CASK,MARK4,NUMB,SYNJ1,JAZF1,RUNX1T1,CCK,DLGAP2,DLGAP1,RCHY1,APPL1,TOX,USP3,ABCC5,EIF4G2,ERBB4,SCML2,SARAF,TDRKH,EML4,PCLO,GRID1,CELF3,KLF12,LRRTM3,KCNMA1,MAPT,MARK1,SESN3,MYO5A,ZC3H12B,NOVA1,KCTD15,MED1,TMEM255A,USP47,RIC8B,ZNF532,SNX22,WDR47,SCN3B,PEG10,NPAS3,CLASP2,SYT1,RPGRIP1L,FRYL,HEY2,CADM1,ZIC1,TRIM9,POLR3H,CADM2,PCBP4" MicroRNA hsa-miR-1197:TargetScan hsa-miR-1197 TargetScan 3.53E-31 1.98E-27 8.64E-31 7.96E-30 57 171 "ADD3,PTCHD1,AK2,MADD,PDE8B,CCAR2,ATP1B3,ATP2B2,CACNA1A,CBFA2T2,REPS2,KIAA1549L,CREM,CHD5,PLCXD3,MTX3,HS3ST2,FARSB,ABI2,EIF5,EPB41L1,EXTL1,PCYOX1,ARFGAP2,CAMKK2,CELF1,GHDC,NCKAP1,PPARGC1A,LYVE1,GRIK3,PTPN5,PAXBP1,MAT2A,MBD1,MMP16,DBNL,MYO6,NFIX,OPCML,PAX6,FAM216A,MAPK10,GTDC1,CYB561D1,KIAA0895L,SCN2A,CLSTN1,CCDC88A,BTBD7,NMNAT2,LHFPL4,GZF1,DAAM2,RBFOX2,FTSJ1,CA10" MicroRNA hsa-miR-431*:mirSVR_lowEffct hsa-miR-431*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.56E-31 2.00E-27 8.72E-31 8.04E-30 84 373 "TTYH1,ADAR,KIDINS220,SLC44A5,ALAD,LTBP4,MRTFA,AMPD2,CACHD1,LGR5,MARK4,BCL2L2,CACNA1D,VXN,RHBDL1,CCNH,ENTPD6,CDK11B,ADGRG1,ASIC3,FADS2,RCHY1,ANKRD44,SNCAIP,FAM131B,MFAP3L,SV2B,GRIN3A,TOM1,YAF2,ABI2,SORBS3,ELN,NCALD,PRMT5,APOPT1,BRSK1,GABRA2,IQGAP2,DISC1,GPR162,GLS,MSL3,NUDT21,CECR2,ATXN2L,HNF4G,HSF2,SCIN,MBD1,MBNL1,NDUFA5,NHLH1,SH3KBP1,PSMD13,TMEM260,PTPRE,ACSS3,RAP1GAP,RFX2,RFX4,C12orf49,RAVER2,LRRK2,ATAT1,SCP2,SEC14L1,NTNG1,ST3GAL3,SUPT5H,FNDC9,SLC37A2,TACC1,ARHGAP9,SIK3,ACTR6,DAAM2,GUSBP1,LGI4,ZIC1,DHX33,EVI5,ZNF248,LAS1L" MicroRNA hsa-miR-150-5p:Functional MTI Functional MTI miRTarbase 3.77E-31 2.12E-27 9.24E-31 8.51E-30 102 534 "AS3MT,XKR4,RNF157,PWWP2A,PTCHD1,ZNF578,PHF12,CDC14B,ARRB2,ARSE,ATP1B3,ATP2B1,ZNF582,MTMR9,LDHD,FOXK1,VXN,CAST,ZBED1,DIS3L,PLAA,COL9A2,ENTPD4,CSNK1E,SOCS5,DNAL1,RABGAP1L,GNE,TOM1,IRAK4,C8orf37,MTSS1L,SLC43A2,MRPL37,TLR7,TBC1D16,TUBB4A,AMOTL2,IP6K2,ANKFY1,APOPT1,TRAF3IP2,RAPGEF6,KIAA1841,FAXC,SRCAP,CRCP,KIF3A,RNF165,MFSD2A,HAS2,HMGB1,ATCAY,NKD1,SLC35G1,METTL21A,KCNK3,MBD1,NFYA,P2RX7,PAK3,TMOD2,PIK3C2A,SMIM7,ZNF426,CNNM2,OCIAD1,ZSCAN2,ZNF844,C12orf49,PGBD4,FOXRED2,DRAXIN,SCN2B,HSPA4L,KANSL3,ZCCHC24,BDP1,ZHX3,SP2,STAC2,KLHL7,WWC1,AGTPBP1,ACSL6,KIAA0930,ZEB1,GPRIN3,ZMAT3,CBX5,PARD3,SYNPO2,SMUG1,RUNDC3B,TRPS1,TSPAN11,LAT2,ZNF708,ZNF70,DPYSL5,MPPE1,GAN" MicroRNA hsa-miR-485-5p:TargetScan hsa-miR-485-5p TargetScan 3.93E-31 2.21E-27 9.61E-31 8.85E-30 77 316 "ADCYAP1R1,BEND6,LRRC7,AMPD3,OGT,CDC42BPA,PPFIA4,CNTNAP1,CCAR2,KSR1,BSN,CAMK2A,LRRFIP1,DLGAP2,LSMEM2,KIAA1549L,ATRNL1,PLXNA4,SDC3,ECE2,ELMSAN1,DNM1,DPH1,DRP2,PLXNC1,RASL10A,CELF1,GABRB3,GGT7,PPARGC1A,GRIN1,PTPRT,ATOH8,CELF3,FRMD5,DDX19B,DISP2,KCNJ11,KCNK3,CAMK2N2,AFF1,DBNL,MDGA1,HS6ST3,MXI1,NOVA1,KCNK10,PDE3A,PLEC,FSD1,POU6F1,MED1,NKAIN4,MAPK4,BCAS3,PTAFR,CYB561D1,PEAR1,CHD9,PEX26,NMNAT2,PEG10,DDN,MAPK8IP3,AJAP1,MMS19,ARHGAP9,HIF3A,FAM124A,MGAT5B,LYPD6,REEP1,CADM2,LRP8,NELFE,PARP11,JMJD1C" MicroRNA "ATGTAGC,MIR-222:MSigDB" "ATGTAGC,MIR-222:MSigDB" MSigDB 4.04E-31 2.27E-27 9.89E-31 9.11E-30 50 129 "RALGAPA1,ARID1A,AXIN2,LRFN2,OGT,SHTN1,ATP1A1,KSR1,QKI,ZNF385A,TOX,RIMS3,DYRK1A,FAM13A,PPARGC1A,FERMT2,AGFG1,CLVS2,KLC1,LIFR,HECTD2,ADAM11,MEIS1,NOVA1,HMGCLL1,KANSL1,MAPK10,ANKHD1,KHDRBS2,SEMA6D,ATXN1,KIF16B,FNDC3A,SYBU,SHANK2,SNCB,TMCC1,CDK19,POGZ,C3orf70,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,TRPS1" MicroRNA "ATGTAGC,MIR-221:MSigDB" "ATGTAGC,MIR-221:MSigDB" MSigDB 4.04E-31 2.27E-27 9.89E-31 9.11E-30 50 129 "RALGAPA1,ARID1A,AXIN2,LRFN2,OGT,SHTN1,ATP1A1,KSR1,QKI,ZNF385A,TOX,RIMS3,DYRK1A,FAM13A,PPARGC1A,FERMT2,AGFG1,CLVS2,KLC1,LIFR,HECTD2,ADAM11,MEIS1,NOVA1,HMGCLL1,KANSL1,MAPK10,ANKHD1,KHDRBS2,SEMA6D,ATXN1,KIF16B,FNDC3A,SYBU,SHANK2,SNCB,TMCC1,CDK19,POGZ,C3orf70,TCF12,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFPM2,TRPS1" MicroRNA hsa-miR-302c-3p:Functional MTI Functional MTI miRTarbase 4.43E-31 2.49E-27 1.08E-30 9.97E-30 99 507 "RNF157,FZD9,SORCS2,OSBPL8,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,CAMK2A,PRC1,ZBED1,DIS3L,CLCN3,IFFO1,IGDCC3,ZNF385A,ENTPD4,SOCS5,UBXN2A,GREB1,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,FEM1B,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,MSANTD4,TRAF3IP2,KIAA1841,SRCAP,MALT1,CRCP,CECR2,GRB10,MFSD2A,HAS2,PTGDR2,HMGB1,IL6ST,KCNB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,LRP12,PRKACB,SLC22A23,OCIAD1,RAD51D,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,TPD52,RGMB,NR2C2,ZNF70,CADM2,WIPF2,MPPE1" MicroRNA hsa-miR-1295:mirSVR_lowEffct hsa-miR-1295:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.64E-31 2.61E-27 1.13E-30 1.04E-29 71 270 "KIDINS220,KLHL13,SMIM17,MRTFA,AMPD2,DDX3Y,DPY19L3,CACNA1D,SLC25A14,MS4A7,MYRIP,DCAF8,ARMCX2,ZEB2,RHOBTB1,DLG2,CDON,DTNB,MAMLD1,ABCC5,EPHB1,DNAJC27,ATP8A1,FCGR1B,TOMM40L,TESK2,CAP2,CHL1,DISC1,GNAS,LPAR4,STMN2,C1QL4,IL6ST,KCNN1,ARHGAP12,MEIS2,TCEAL5,NAP1L3,NNAT,TBC1D25,FTO,STRN3,FAT3,MASP1,QRICH1,PTPRN2,ACSS3,VEPH1,PBRM1,ROBO1,KIAA0895L,CCDC112,CSRNP3,ASIC4,NTNG1,FNDC3A,BCAN,PPP4R3A,SEPHS1,RAB3GAP1,MAST1,SMARCC2,PDZD2,ZSWIM8,SP4,KAZN,DOCK9,MTMR14,PLPP4,ZNF213" MicroRNA hsa-miR-1205:PITA hsa-miR-1205:PITA_TOP PITA 4.74E-31 2.67E-27 1.16E-30 1.07E-29 65 226 "ASIC1,ADCY6,CCDC85A,AMPH,SLC4A4,KIF1A,CACNA1A,HAP1,CAMK2G,RUNX1T1,KMT2C,CNTFR,SNPH,SMG7,SRGAP3,G3BP2,CALN1,TMEM132E,TENM1,GPHN,BRSK1,ARFIP1,TNRC6A,RAPGEF1,ADAMTS8,KCND2,KCNMA1,MBD1,MEF2C,MSI1,MYO7A,PABPC1L2A,CNOT4,CCSER2,RETREG1,TMEM260,RIPOR1,ARID4A,SEMA6D,SATB1,ATXN1,SCN2A,PRCD,SH3GL2,BTBD3,WDTC1,MYT1L,SOX11,NMNAT2,LRRC4,MAPK8IP3,ASTN2,MCF2L,FBXW11,RPGRIP1L,AZIN2,ARHGEF12,FRYL,TPM3,PCDH20,LAMP5,ZFAND5,SLC30A4,GDPD5,WNK3" MicroRNA hsa-miR-1300:PITA hsa-miR-1300:PITA_TOP PITA 5.11E-31 2.87E-27 1.25E-30 1.15E-29 72 278 "GPR158,TAOK1,LRRC7,PITPNM2,LCORL,PPFIA4,API5,CADPS,MTMR9,ADGRB3,BCL7A,TMEM257,MAGI1,CACNA2D2,CLTC,HECTD1,HOMER3,SEC24C,CTNND2,ZFYVE16,ELMSAN1,SMG7,DLG4,DMD,DYNC1I1,SIDT2,EGR3,ATP8A1,FGF13,UBE2E3,AFF2,FUT9,ARFIP1,GHR,RND1,TCERG1,GPM6A,EML4,BACH2,PLD5,KIF5A,AQP11,MPP2,NBL1,CNOT4,GPR137C,CAMKV,PLP1,TNPO2,PPP2R5E,RELN,PTCH1,FIGN,RGS4,ZFHX4,NCBP3,NLGN1,FAM81A,WDR47,KDM3A,PEG10,CAMTA1,TCF4,RPGRIP1L,TCF12,CADM1,TCEAL7,REEP1,SYNC,WIPF2,FZD3,HNRNPA3" MicroRNA hsa-miR-4286:mirSVR_highEffct hsa-miR-4286:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.33E-31 2.99E-27 1.30E-30 1.20E-29 86 392 "RALGAPA1,XKR4,ADCY6,ADD1,PWWP2A,SPTBN4,ATP1A3,SLC4A4,PRMT9,GPC2,CALB2,PTBP2,MTMR7,LRBA,ENTPD4,SEC24C,ST18,NOS1AP,FGFR1OP2,HS3ST4,PDCD6IP,DTNA,ELAVL2,EPS8,DENND4A,ABCA8,FAM198B,EFEMP1,TOMM40L,ARFGAP2,GABBR1,GABRA3,TRAF3IP2,TMEM8B,RND1,TNRC6A,CBX1,GRID1,MAEL,MSL1,DISP2,KCNC1,KCND1,KCND3,MAN2A2,MBNL1,RSPO2,NFE2L2,NPTX2,PDE4A,STRN3,TMEM104,WDR25,BDNF-AS,RGS3,SEC61A2,RPRD1A,ROBO1,RORB,PCMTD2,ADAL,WLS,ITSN1,HKDC1,PPP4R3A,DMRTC1,SMARCE1,SNCA,SOX3,KIF1B,LRRC4,TACR1,MCF2L,ADGRL3,TBX15,KHDC1,C5orf64,TTTY15,HEPACAM,SLC35A4,LGI4,FSTL5,SH3GLB2,SMIM8,CASC15,MSRB3" MicroRNA hsa-miR-1272:PITA hsa-miR-1272:PITA_TOP PITA 6.50E-31 3.65E-27 1.58E-30 1.46E-29 64 220 "RALGAPA1,SLC24A4,APAF1,ARNTL,ATP2B1,JAZF1,NIPA1,MAGI1,CCPG1,FOXN3,NMT2,CNR1,AKAP6,DGKB,DNAJC6,DLG3,SLC12A6,KCTD3,HPCAL4,AFF2,HBS1L,TNRC6A,EML4,PCLO,ADAMTS6,NCKAP1L,NEGR1,SMAP1,STXBP5,MXI1,NOVA1,CDK14,STRN3,MED1,PTPRD,PEX5,OXR1,PBRM1,AP1AR,ATXN1,TNFRSF19,AMBRA1,CHD9,SLITRK3,SLC8A2,CCDC88A,SP4,PEG10,CLASP2,ST5,RHBDL3,POPDC3,ATP11A,CAMSAP2,TCF4,TCF7,RIMBP2,LRP8,STMN4,PRDM10,WNK3,RTN4,PAK5,FRMD6" MicroRNA hsa-miR-147:PITA hsa-miR-147:PITA_TOP PITA 6.85E-31 3.85E-27 1.67E-30 1.54E-29 54 154 "SLITRK1,NLGN4X,ANK1,ANK3,MAP4K3,APP,ATP1A1,CACNA1A,CALM1,LDB2,AKAP6,CABP1,CREB5,SPOCK2,ZEB2,SMG7,DMTF1,KMT5B,ELN,EVL,TMEM151A,AHCYL1,BRPF3,RND1,KDM2B,GPD1,GRIN2D,NR3C1,HSF2,ZIC5,L1CAM,NCAM1,NEUROD2,NF1,NFIA,ZNF827,PDPK1,PLP1,TNPO2,MINDY2,PRIMA1,ROBO2,SLC1A2,PPP4R3A,TET1,STXBP1,CAMTA1,TCF4,SLC44A1,THRA,NR2C2,CADM1,FLRT2,ADAMTS10" MicroRNA "CAGCACT,MIR-512-3P:MSigDB" "CAGCACT,MIR-512-3P:MSigDB" MSigDB 7.12E-31 4.00E-27 1.74E-30 1.60E-29 53 148 "SPOP,PCDH10,PITPNM2,PPFIA2,ATP2B2,PTBP2,CCKBR,USP6,FOXN3,KMT2C,QKI,ARHGEF10,PLEKHM1,KLHL3,SGSM2,MBNL2,ETV1,OGA,GRM7,PTPRT,HLF,MAT2A,MBNL1,SEMA5B,TRHDE,PRRX1,RETREG2,PPP2R5E,PPP3CA,USP47,ACER3,SYNDIG1,ATXN1,ATXN7,NTNG1,MYT1L,IZUMO4,CDK19,CAMTA1,TAL1,TRIM2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ZFP91,ZNF24,STMN4,MARCH8,KAT6A" MicroRNA hsa-miR-4279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.37E-31 5.27E-27 2.28E-30 2.10E-29 97 493 "AS3MT,FAM43B,RNF157,GRAMD1B,ZNF578,CDC14B,SLC7A14,KIAA1614,SEMA4G,DNAH17,SLC4A4,ALDH7A1,FOXK1,IGLON5,HINFP,RGS6,CSNK1E,KIAA0408,FRMPD4,G3BP2,RABGAP1L,USP3,WDPCP,CNNM1,HEYL,OPTN,MRO,MRNIP,RGS17,EMX2,PLEKHO1,EPHB1,SLC43A2,FKTN,FDFT1,FOXO3,AFF2,CELF1,TMEM151A,FAXC,PCDH17,CRCP,KIAA1958,CNDP1,GPR26,GRK4,KIF3A,RNF165,IL1RAPL1,ZDHHC15,NEGR1,EID2B,C2CD4C,KCNJ11,KPNA5,LAMP2,LIMS1,NCOA7,LSAMP,AFF1,NPTX2,FAM216A,POU6F1,EPDR1,APTX,PTPRB,TMEM231,ZNF844,NWD1,GTDC1,PGBD4,FAM192A,SCN2B,STUM,ZFP30,PEX26,PALLD,CLUAP1,UHRF1BP1L,UNC5B,AGTPBP1,TPCN2,PCDHA6,ZNF106,ARL10,TLR4,ERCC6L2,TNS1,TMPRSS5,AGMO,ZNF70,PMEPA1,STMN4,LMAN2L,WIPF2,MPPE1,GAN" MicroRNA hsa-miR-125a-3p:PITA hsa-miR-125a-3p:PITA_TOP PITA 1.01E-30 5.65E-27 2.45E-30 2.26E-29 57 174 "ADD3,KLHL13,SYNJ1,LDLRAD4,LDB2,DGKI,CFL2,BTF3L4,SIPA1L1,RIMS4,ARHGAP24,DGKG,HP1BP3,G3BP2,DPYSL2,EVL,NPTN,FYN,MEGF11,GATM,GNG3,PRRC2B,PRDM5,ELOVL5,KCNA1,KIF2A,MBD1,LRP1B,MEF2C,MITF,NF1,CNOT4,PCDH8,CCSER2,PKIA,MSANTD2,RGS4,SGK1,NLGN1,FAM214B,SLC8A1,RAB3GAP1,MYT1L,LMO3,EPB41L3,GANAB,ZC3H4,EXOC7,SZT2,MTMR14,TRPS1,FAM155A,AMOT,BEST1,MAP3K12,CADM2,FXR1" MicroRNA hsa-miR-662:mirSVR_lowEffct hsa-miR-662:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.01E-30 5.67E-27 2.46E-30 2.26E-29 92 448 "RNF157,MTA3,ALAD,MRTFA,SUGT1P4-STRA6LP-CCDC180,APBA2,SLC2A11,ADAM23,ADAM15,BCL2L2,SYNJ2,CACNB2,CALB2,USP6,RAB33A,TPP1,SLC4A8,ARHGEF10,CNTNAP2,NOS1AP,KATNAL2,KIF26A,DCTN1,MFAP3L,RABGAP1L,DMPK,EBI3,TUBB3,ATP8A1,CAMSAP1,ATP13A4,FLT1,DCTN2,WDR83,KHDRBS3,LRRC37A6P,CPLX2,ARFIP1,ADAM28,GGT7,GNAS,FAM107A,FAM222A,NXPH2,HES5,KCNMA1,KLC1,MBP,CHIC1,PPM1L,MOBP,GIT1,NOS1,NTRK2,OGDH,ZDHHC22,PIK3CD,PIK3R1,ZFYVE21,PNMA3,SDK2,SEPT4,TNPO2,POU6F1,LRRN3,WBP1L,BDNF-AS,RGS12,MEG3,SCP2,TRIM46,ZFP30,AMBRA1,ST3GAL3,EPN2,SLC6A8,SON,IDI2-AS1,KIF1B,C11orf87,COLGALT2,NKAIN2,TAL1,TNS1,TRIO,UBE3A,MGAT5B,BEST1,SPIRE1,MEIS3,MVB12B,JPH3" MicroRNA hsa-miR-6779-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-30 5.72E-27 2.48E-30 2.28E-29 115 667 "XKR4,ADAR,PLEKHH1,TXNDC16,AK2,TRMT9B,PHF12,AQP6,ARRB2,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,ANKRD13B,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,PRRC2B,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA hsa-miR-383:PITA hsa-miR-383:PITA_TOP PITA 1.04E-30 5.82E-27 2.52E-30 2.32E-29 51 137 "GALNT13,SORCS1,MTUS1,OGT,ZBTB10,CACNB4,DCLK1,FOXN3,PLCXD3,BLOC1S6,SACS,SV2B,EDN1,ELAVL2,ELN,PAN3,TAOK3,CSPG5,GABRB3,NCKAP1,PCDH17,GLS,MEF2C,NCAM1,ZC3H12B,NEUROD1,NNAT,CNOT4,NRGN,PIK3R1,RETREG1,MAPKAP1,STRN3,NXPH1,TMEM260,PTPRE,UBR7,SOX6,PPP1R9A,SHMT2,AMBRA1,SLC1A2,FAM126B,SOX5,CDK19,RBM26,TCF4,FRYL,DICER1,TRPS1,FNDC5" MicroRNA hsa-miR-648:PITA hsa-miR-648:PITA_TOP PITA 1.17E-30 6.57E-27 2.84E-30 2.62E-29 56 168 "CSMD3,BCAR3,MAP4K3,BCL7A,CALM1,PTBP2,EVI5L,HECTD1,SLC35F1,CTNND1,PUM1,FRMPD4,HDAC4,RIMS3,SV2A,CPEB2,ZIC4,DLC1,TACC2,FUT9,CAB39,GPD1,GPM6A,GRIA2,BACH2,NEGR1,PLD5,USP54,ARHGAP12,MARK1,MAT2A,MBNL1,MEIS1,AFDN,NCAM1,GPR88,PRRX1,RAB5B,ROBO2,SCN2A,ARX,CPEB4,MBD5,DDN,POGZ,ANO4,TBX15,SATB2,ARHGEF12,LRRC8A,FLRT2,TMEM237,EMSY,PDSS2,JMJD1C,PIANP" MicroRNA hsa-miR-636:PITA hsa-miR-636:PITA_TOP PITA 1.18E-30 6.64E-27 2.87E-30 2.65E-29 58 181 "ABR,ACTN1,RTL9,OSBPL8,SEMA6A,ANK1,SHTN1,NUMB,DPY19L3,VSTM2A,DCLK1,LGI1,HAPLN1,PUM1,USP6NL,GAPVD1,RIMS3,DNAJB6,DYRK1A,MBNL2,PAN3,EMX2,EPB41L1,RTN3,NRN1,GRIK2,RNF165,TMEM25,FAM222A,ATXN2L,BACH2,LIFR,NOVA1,OPCML,PCDH9,LRP12,PKN2,QRICH1,TMEM260,ZYG11B,AMER2,FAM214B,RIMS1,SOX5,CEP68,PLCB1,SYT1,TBX15,TCF4,DOCK9,FRYL,HEY2,TNS1,TPD52,TUB,TRIM9,KAT6A,MSRB3" MicroRNA hsa-miR-5006-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-30 7.43E-27 3.21E-30 2.96E-29 69 259 "AS3MT,XKR4,ADCYAP1R1,MTA3,SORCS2,AK2,SPOP,CACHD1,SEMA4G,ASGR1,BCL7A,BID,CACNA1G,MYRF,LURAP1,CAMK2G,SYT6,DNAJB5,RGS6,IPCEF1,CHD5,PHF19,CHRDL1,RCAN1,FEM1B,CELSR3,AMOTL2,SRCAP,GLUL,TPPP,NR3C1,PTPRT,PADI2,NEGR1,EID2B,LSAMP,MDFI,NFIA,NOVA2,NPTX1,GLIPR1L2,PHKG1,KANSL1,MARCH1,SH3TC2,ZYG11B,DPF2,RORB,ELP2,TMEM156,ATXN1,ASIC4,MYO18A,BCAN,BTBD3,LRRC55,SLC11A1,ZCCHC24,ZBTB43,SMOC1,ACSBG1,TCF7L2,SEZ6L,TMEFF2,TOM1L2,ZNF177,VANGL2,ZDHHC20,DPF3" MicroRNA hsa-miR-598:mirSVR_highEffct hsa-miR-598:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-30 7.43E-27 3.21E-30 2.96E-29 69 259 "ASPHD1,KDM5D,ARID1A,ADD1,SLC44A5,CCDC146,ATP2A2,ZMYM4,CHGB,CASC2,NDST3,AKAP7,SLC4A8,ZFP28,CNRIP1,NECTIN3,CNTNAP2,USP6NL,TOX,ZEB2,GPR61,CLVS1,CEP78,MED12L,GABRB1,C15orf41,ALDH1L1,TOX3,GPM6B,ZNF678,KCND2,CYP27C1,MAP6,MITF,MN1,GPR137C,HMGCLL1,SLC26A11,SIDT1,PTPRZ1,OXR1,ZDHHC14,RFX4,CCDC82,FBXW7,SH3GL3,KIF16B,NLGN1,IFT122,SNCA,SNRPN,SPTB,VPS13A,MCF2L,CRB1,TIAM1,RBFOX2,ZMYND8,PPIL6,DCBLD1,RUSC1,TSN,FAM181B,PLEKHH2,SPIRE1,WNK1,CADM2,SCG2,MSRB3" MicroRNA hsa-miR-574-3p:mirSVR_lowEffct hsa-miR-574-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.35E-30 7.58E-27 3.28E-30 3.02E-29 80 346 "AP2A1,SUGT1P4-STRA6LP-CCDC180,KCNAB2,MADD,SLC2A11,DPY19L3,MPDZ,DCAF5,BMPR1B,SYNJ2,CAMK2G,REPS2,TIGD7,TAOK2,COL9A1,SMARCAL1,CHD1L,VCAN,ERC2,ARHGEF4,TOMM20,DNM1,DNM2,DPP6,DPYSL2,FRY,EGFR,RCAN2,SPEG,FHL1,POLK,SUCO,MEX3B,FOXF2,PRELID3A,ARFIP1,GFRA2,CSDC2,SPIN1,GPD2,SOX21,BTBD17,C5orf24,MAP2,KITLG,MMP16,LAYN,NCAM1,NDUFA5,PDE2A,PIK3R1,PMP22,MINDY2,PRKAR1B,PRKCB,PRKCZ,WBP1L,RASGRF1,ARHGEF10L,DCUN1D2,CCDC25,SBF1,NAXD,SNRPN,ADAMTS17,TCF4,ZEB1,TPCN2,SYNE1,NAT16,CDK20,TRH,CLHC1,TUBB1,NSD2,SPIRE1,PCBP4,UBE3B,SMIM8,DPF3" MicroRNA hsa-miR-375:Functional MTI Functional MTI miRTarbase 1.40E-30 7.85E-27 3.39E-30 3.12E-29 95 477 "USP31,OSBPL8,SPOP,DGKD,ARHGDIA,NUMB,INSYN2B,EIF4G3,BSN,SPAG9,ZBED1,CDC42,CRLF1,CFL2,CHGB,RAB28,CNN3,AKAP7,SEC24C,SNPH,KIAA0513,TBC1D5,RIMS3,TMEM170A,DLG4,ANKRD46,SYT15,PHF20L1,ABI2,ELAVL2,ELAVL4,GPHN,ERBB2,RRAGB,F3,ACSL4,SYNCRIP,NELFCD,CAB39,AHCYL1,C15orf41,SESN1,NUDT21,RAPGEF1,TMEM25,PSIP1,ATOH8,RASSF8,HSP90AA1,RBPJ,DISP2,JAK2,KCNQ2,KHK,NCOA7,AQP11,POC1B,MYCN,NCAM1,IDNK,ODF2,OPA1,NLE1,MAPKAP1,MINDY2,MAPK3,TMEM145,PPP2R3C,RBBP8,YY1AP1,DGLUCY,CCDC88A,GKAP1,FAM126B,SON,SOX2,NXT2,NSFL1C,KLHL7,WWC1,AGTPBP1,IQCE,RPGRIP1L,TCF12,FAM200B,THRA,HEY1,ZFP91,TNS1,TRPS1,UBE3A,USP1,ZNF540,PHTF2,NETO2" MicroRNA hsa-miR-514:PITA hsa-miR-514:PITA_TOP PITA 1.42E-30 7.97E-27 3.44E-30 3.17E-29 57 175 "C6orf89,NCOA1,REPS2,TAOK2,NRXN3,BTF3L4,MYRIP,ERC2,NR1D2,FSD1L,SH3GLB1,EIF1,EPS8,TAOK3,PRKAG2,SUCO,SYNCRIP,ARFGAP2,TNRC6A,INSM2,LPAR4,TPPP,GRIA2,NR3C1,LRRTM3,KCNB1,NCOA7,SESN3,NEXMIF,TMEM260,PTPRG,PTPRZ1,RAB3A,RFX3,BAALC,ZC3H14,RTN1,SCN2A,SCN3A,FNDC3A,SON,SULF2,SYT11,ARHGEF9,TAC1,TCF4,TRIM2,TCF12,PCDHB6,DDHD1,AMACR,CADM1,EIF4ENIF1,ZIC1,NAV3,HNRNPA3,NETO2" MicroRNA hsa-miR-647:PITA hsa-miR-647:PITA_TOP PITA 1.42E-30 7.97E-27 3.44E-30 3.17E-29 57 175 "ARID1A,SPOP,ALCAM,ASCL1,NCOA1,DDX3Y,CADM3,ADGRB1,KALRN,CAMK2G,DCLK1,ZNF521,IGDCC3,SH2B1,PDE4DIP,FRMPD4,LYPD1,CPEB2,DPYSL2,FAM78B,PHC2,EGR3,TMEM35A,DNAJC27,CLVS1,ATP8A2,TNRC6A,GRIA2,RNF165,HPCA,KPNA5,INSYN2,GIT1,NFIX,NOVA1,ZNF827,CDIP1,PRRX1,MED1,WBP1L,PTPRB,DUSP15,GTDC1,ZFHX4,ELMO2,SOX11,POGZ,SS18,STX1A,C3orf70,TBX15,R3HDM1,TRPS1,CADM1,PITPNB,CA10,PIANP" MicroRNA hsa-miR-492:mirSVR_highEffct hsa-miR-492:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.50E-30 8.44E-27 3.64E-30 3.35E-29 74 298 "RALGAPA1,ASIC2,ADORA2A,KCTD16,MYH7B,KCNAB2,ATP6V1G2,KALRN,CD38,DGKI,NDST3,TMEM155,HINFP,CTNND2,CCDC144A,RIPOR2,TOX,ARMCX4,MAGI2,ZC3H11A,NTM,G3BP2,MAMLD1,DYRK1A,C8orf37,EPHA5,ZCCHC17,GABRA2,GABRB1,DISC1,USP19,PCDH11X,DCLK2,GNAL,LPAR4,MFSD2A,KCNB1,MAT2A,MATN3,ADAM11,PPM1L,MTTP,LAYN,NDUFA5,SMIM11A,IGSF11,SH3KBP1,PIGG,TMEM260,SLC25A48,ZYG11B,YY1AP1,SPIN3,ATP8B4,CSRNP3,SUPT20H,TRA2B,NTNG1,ST3GAL3,ZNF365,SMARCE1,SP4,FCHO1,NEK4,TMEM150C,SYN2,WDR7,AP4E1,SLC44A1,TNS1,VSNL1,TFIP11,RNF103,FIP1L1" MicroRNA hsa-miR-376a-3p:TargetScan hsa-miR-376a-3p TargetScan 1.54E-30 8.67E-27 3.74E-30 3.44E-29 61 202 "DSCAML1,BEND6,ABCD2,PITPNM2,ANK2,DCAF5,CDK5R1,AIFM1,BAG4,FAM131B,CCDC144A,PYGO1,HDAC9,IP6K1,JAKMIP2,COPS7A,GRIN3A,ABI2,EML1,EN2,FGFR1,POLK,KHDRBS3,GAB1,PCDH17,FERMT2,GPR22,GRIK2,GRIK3,GRM5,IL1RAPL1,HAS2,KLF12,HES5,METTL21A,CLVS2,LAYN,HCN1,PAX6,PIK3R1,LRP12,EXOSC10,MED1,PRKACB,PTHLH,GAL3ST4,ARMC5,HUNK,AMER2,SATB1,CHD9,FBXO11,MBD5,FAM126B,CDK19,CLASP2,CUX2,DDHD1,CABIN1,ELP5,PPP1R3F" MicroRNA hsa-miR-376b-3p:TargetScan hsa-miR-376b-3p TargetScan 1.54E-30 8.67E-27 3.74E-30 3.44E-29 61 202 "DSCAML1,BEND6,ABCD2,PITPNM2,ANK2,DCAF5,CDK5R1,AIFM1,BAG4,FAM131B,CCDC144A,PYGO1,HDAC9,IP6K1,JAKMIP2,COPS7A,GRIN3A,ABI2,EML1,EN2,FGFR1,POLK,KHDRBS3,GAB1,PCDH17,FERMT2,GPR22,GRIK2,GRIK3,GRM5,IL1RAPL1,HAS2,KLF12,HES5,METTL21A,CLVS2,LAYN,HCN1,PAX6,PIK3R1,LRP12,EXOSC10,MED1,PRKACB,PTHLH,GAL3ST4,ARMC5,HUNK,AMER2,SATB1,CHD9,FBXO11,MBD5,FAM126B,CDK19,CLASP2,CUX2,DDHD1,CABIN1,ELP5,PPP1R3F" MicroRNA hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-30 1.07E-26 4.59E-30 4.23E-29 77 323 "SERPINA3,AS3MT,ACTN2,GRAMD1B,NLGN4X,MTA3,SORCS2,SPOP,ASCL1,ATP1A3,ATP2B1,PROM1,CABP7,CD86,CDH8,GPR37L1,CLU,CST3,PLXNA4,PITPNM3,KIAA0408,GAPVD1,SMG7,RCAN1,ELAVL3,EMX2,NRN1,GABRA1,GABRG2,GALR1,PCDH17,GJB1,GPR26,PARD3B,GRID1,PTGDR2,FRMD3,LSAMP,CD200,DDR2,ZDHHC22,PALM,PDE3A,GDAP1L1,PLCL1,CRLS1,KANSL1,SNRK,RDX,ZYG11B,SCN2B,ZFP30,CPEB3,ZFP1,IGSF9B,LIMCH1,SS18,DIP2A,SEPT3,ARHGEF9,ANKRD28,EXOC7,MGRN1,TMEM151B,TGFBR3,HHIP,FBXL16,BHLHB9,TNS1,TSC1,UBE2H,ZNF708,CADM2,PRDM10,NAV2,MPPE1,DPF3" MicroRNA hsa-let-7e-5p:Functional MTI Functional MTI miRTarbase 1.95E-30 1.10E-26 4.72E-30 4.35E-29 109 612 "ARID1A,FZD9,MTUS1,ZNF578,AMPD2,USP37,AQP6,IGDCC4,SLC2A11,BACH1,JAZF1,BTRC,SPAG9,RUNX1T1,FMNL3,CDH18,CLTC,CRY2,APPL1,DCAF8,MATR3,DNAL1,ELMSAN1,MTX3,ARNT2,DNAH9,SHANK1,DTNB,E2F6,EDN1,ANKRD46,SUGP2,EIF4G2,EN2,PLEKHO1,KATNAL1,TUBA1B,TUBB4A,TOMM40L,TRMO,TMEM107,PDLIM5,CELF1,SALL3,DISC1,GATM,GLUL,POLL,GPM6B,FUT10,RABL2A,ARHGAP19,ATXN2L,HMGB1,IGF1,IL6R,KPNA5,NAT8L,MDM4,THYN1,MYCN,NAP1L1,NF1,NME4,SLC11A2,NUCB2,OPRL1,PSMA6,UHRF1BP1,PTK2,QDPR,USP47,BSDC1,RDX,FIGN,C12orf49,SALL1,ATXN2,KIF27,CHD9,FNDC3A,DZIP1,SLC12A4,SCMH1,RCOR3,PEG10,MCF2L2,FNDC9,SYT1,TCF4,KIAA0930,SLC19A3,PSD3,NSD1,AHCYL2,TGFBR3,MTMR14,CBX5,LRRC8A,RBFOX2,TUBB2A,UBE2H,ZNF28,ZFAND5,SMARCAD1,C12orf4,FAM219B,JMJD1C,SPATA13" MicroRNA hsa-miR-122*:mirSVR_highEffct hsa-miR-122*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.06E-30 1.16E-26 4.99E-30 4.59E-29 64 224 "ACADM,PPFIA2,CDC14B,KALRN,RUNX1T1,CERS5,CHM,ARMC8,COL11A2,CHD1L,HAPLN1,SOCS5,ARMCX4,C8orf34,FBXO25,SPOCK3,NTM,ARRDC4,AASS,LRRC17,CAMKK2,CAB39,MSTN,PCDH11X,LUZP2,NUDT21,GRIA2,HMGB1,KCNK2,KTN1,LMO1,MAT2A,SYT9,POC1B,BLOC1S2,BCO1,NELL1,TBC1D25,GPR88,KCTD15,GPSM2,MED1,TMEM255A,USP47,SLC6A15,SETD5,ROBO2,RIMS1,SNAP25,TNIK,BDP1,TSPYL2,RBM26,TROVE2,ELOVL4,SYP,RPGRIP1L,DCBLD1,RICTOR,PCDH20,ZBTB14,LYPD6,SCG2,TRIM16L" MicroRNA hsa-miR-4292:mirSVR_highEffct hsa-miR-4292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.08E-30 1.17E-26 5.03E-30 4.63E-29 86 399 "SLC12A5,FAHD2CP,MTUS1,PKP4,N4BP2L1,CARMIL3,DST,CERS5,CIART,LSMEM2,TMEM59L,CNTFR,CLIP3,SNCAIP,NCAN,CX3CR1,ARHGAP24,TM9SF4,TBC1D5,ARMCX4,ZEB2,RHOBTB1,RABGAP1L,CHRDL1,SLC29A4,DRD1,ACOT8,SNX29,PHF20L1,DCTN4,EPS8,ERBB2,EYA1,ZNF589,FGF1,IQCG,NBEA,TACC2,AK8,HHIPL1,GABRB1,TMEM8B,GHR,GLDC,RAPGEF4,KAT7,MAEL,ARHGAP36,KNDC1,KCNH2,STXBP5,MAT2A,SYT9,MYL3,TREM2,SEMA5B,SEPT4,POU3F2,PPP2R5C,PPP3CB,MAPK10,SLC26A11,PTPRE,RAP1GAP,RORB,RPE,SH3BGR,EPN2,WDR47,LRRC55,CCDC88A,SOX5,SS18,TBX15,RPGRIP1L,DAAM2,SEZ6L,RPL7L1,UGT8,OSBP2,PLPP4,SLC26A10,XKR7,ADAMTS9,ST7,CASC15" MicroRNA hsa-miR-4755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-30 1.24E-26 5.34E-30 4.92E-29 69 261 "AS3MT,XKR4,ADCYAP1R1,MTA3,SORCS2,AK2,SPOP,CACHD1,SEMA4G,ASGR1,BCL7A,BID,CACNA1G,MYRF,LURAP1,CAMK2G,SYT6,DNAJB5,RGS6,IPCEF1,CHD5,PHF19,CHRDL1,RCAN1,FEM1B,CELSR3,AMOTL2,SRCAP,GLUL,TPPP,NR3C1,PTPRT,PADI2,NEGR1,EID2B,LSAMP,MDFI,NFIA,NOVA2,NPTX1,GLIPR1L2,PHKG1,KANSL1,MARCH1,SH3TC2,ZYG11B,DPF2,RORB,ELP2,TMEM156,ATXN1,ASIC4,MYO18A,BCAN,BTBD3,LRRC55,SLC11A1,ZCCHC24,ZBTB43,SMOC1,ACSBG1,TCF7L2,SEZ6L,TMEFF2,TOM1L2,ZNF177,VANGL2,ZDHHC20,DPF3" MicroRNA hsa-miR-223-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-30 1.25E-26 5.37E-30 4.95E-29 72 284 "ADD2,NLGN4X,HACE1,TAOK1,PCDH10,ARRB1,ATP2A2,THSD7A,RUNX1T1,SEPT7,CFL2,IGLON5,ACBD5,PPP1R16B,DBT,JAKMIP2,SV2B,DMD,MBNL2,ABI2,EPHA5,KATNAL1,FGF14,UBE2E3,MSANTD4,C15orf41,MMADHC,GLI2,CBX1,BVES,ZDHHC15,IGF1,DOCK7,IL6ST,KCNJ3,KLHL23,KCNQ3,LIFR,SMAD9,CHIC1,MKLN1,MYO5A,NEXMIF,NCAM2,NELL2,GPR173,ZNF655,CCSER2,PLP1,SPATA6,PROX1,RGS4,FBXW7,SATB1,CSRNP3,FNIP1,SMTN,SOX5,ZHX3,NECAB1,ARHGEF9,PLCB1,ALG1,MGRN1,TRIM2,TMEM151B,HHIP,LRTM2,KCNK12,ADAMTS9,KAT6A,SSPN" MicroRNA hsa-miR-98-5p:Non-Functional MTI Non-Functional MTI miRTarbase 2.24E-30 1.26E-26 5.39E-30 4.97E-29 126 786 "ABCF1,ACADM,ARID1A,FZD9,MTUS1,AK2,ZNF578,SPARCL1,CDC42BPA,AQP6,IGDCC4,ARRB1,ZBTB10,BACH1,FMNL3,ADGRG1,PPT2,CRY2,LRIG1,CTNND1,DOCK4,GAPVD1,DNAL1,ZBTB24,MED24,POM121,SACS,MTX3,USP3,DNAH9,ECM2,DUSP9,ABCC5,E2F5,E2F6,EDN1,ANKRD46,MBNL2,EIF4G2,PLEKHO1,GMPR2,TUBB4A,TOMM40L,SEC24B,TMEM164,IP6K2,NELFCD,TRMO,PDLIM5,CELF1,OGA,TRAF3IP2,SALL3,DISC1,GATM,GCNT2,PPARGC1A,TCERG1,DBF4,RAB30,POLL,FUT10,GPR37,RAPGEF4,DIDO1,BTN2A1,RABL2A,IFI16,IGF1,IL6R,DIPK1A,KPNA5,LIFR,NAT8L,MDM4,MEIS1,MITF,THYN1,NAP1L1,CNOT4,SLC11A2,NUCB2,OLR1,OPRL1,NLE1,SCHIP1,QDPR,USP47,RDX,FIGN,LGR4,ATXN2,KIF27,FNDC3A,SEC31A,BTBD3,COA1,SMARCA4,PEG10,MCF2L2,TAB2,ST5,PRRC2C,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,DICER1,TGFBR3,CBX5,TNS1,RBFOX2,SMUG1,PDSS1,TUBB2A,ZNF28,ZNF74,ZFAND5,SMARCAD1,SCG2,NAV2,C12orf4,FZD3,SOCS4" MicroRNA hsa-miR-626:PITA hsa-miR-626:PITA_TOP PITA 2.35E-30 1.32E-26 5.66E-30 5.22E-29 51 139 "SEMA6A,SPOP,SHTN1,STK33,HAP1,MAGI1,TPP1,CNR1,COL4A5,RBM39,TENM4,OSBPL3,CEP170,MAGI2,ZC3H11A,DLG2,PAN3,GPHN,CAMKK2,ARFIP1,ZHX1,BACH2,KIF2A,MBNL1,MEIS2,MITF,HCN1,GNG2,MAPK3,RAB5B,NUDT11,ZC3H14,PPM1E,SEPHS1,SHANK2,TMCC1,ZCCHC24,SOX11,ZSWIM8,HECW1,LRRC4,NCDN,C3orf70,PLCB1,SYT1,SLAIN1,OSBP2,SF1,ZBTB14,ZBTB38,PDSS2" MicroRNA hsa-miR-7977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-30 1.52E-26 6.51E-30 6.00E-29 114 664 "NCKAP5,PLEKHH1,SLC24A4,HECW2,TXNDC16,ZNF578,TRMT9B,SEMA7A,APAF1,CPNE5,AQP6,ZNF582,SYNJ2,ISPD,CBS,SLC16A4,CBFA2T2,REPS2,LONRF2,NDST3,ZFYVE9,AKAP5,PPP1R16B,APPL1,GREB1,ZSCAN23,NOS1AP,MYADM,DNAL1,ELMSAN1,MRO,PLEKHA1,IGSF6,ZNF585B,SCML2,ZNF589,FGFR1,ANKFY1,NSG1,PNMA2,TRAF3IP2,MTHFD2,GNG4,GRK4,KIF3A,BVES,RNFT2,IRAK3,NEGR1,RAB41,ZNF546,IGF1,DOCK7,IBA57,METTL21A,KCNJ5,KLHL23,KIF5A,FGFBP3,MATN3,PPM1L,SAMD5,ZC3H12B,OLR1,SNTG1,FTO,ZNF426,STRN3,FAT3,APTX,RAB5B,CEP97,ZMAT4,PRRT2,C12orf49,ALG9,ELP2,RTKN,NCBP3,CSRNP3,ZFP30,SH3BP2,R3HDM2,CLSTN1,SLC1A2,SLC2A5,SEPHS1,ZKSCAN3,INAVA,FAIM2,UHRF1BP1L,MCF2L2,SRPK2,SS18,MPRIP,ZSCAN29,AKNA,CYB561A3,MTMR14,CBX5,ERCC6L2,TPM3,RFTN2,TUBB2A,RPL7L1,ZNF708,ZNF17,ZNF154,EVI5,SNX27,WIPF2,FBXO36,ZDHHC20,GAN" MicroRNA "TTTGCAG,MIR-518A-2:MSigDB" "TTTGCAG,MIR-518A-2:MSigDB" MSigDB 2.74E-30 1.54E-26 6.59E-30 6.07E-29 60 197 "DSCAML1,OSBPL8,ANK2,EIF4G3,DCAF5,USP6,CBFA2T2,KMT2C,QKI,HECTD1,NCOR1,HDAC4,DAPK1,IP6K1,PLEKHM1,FBXL5,PLPPR4,CPEB2,FAM78B,DYRK1A,FAM135B,EGR3,EPB41L1,AFF2,SORBS1,ZMAT1,STAG2,HMGB1,AGFG1,LAMP2,MEIS1,MEIS2,NOVA1,EPB41L4B,PACSIN1,LRRN3,PRKAB2,CNNM2,PLEKHB2,PBRM1,DOCK10,CHD9,CPEB4,SPART,SRPK2,LARP4,PLCB1,ANKRD28,ATP11A,TACC1,CAMTA1,SATB2,TCF12,R3HDM1,AMACR,SF1,ZIC1,CA10,PMEPA1,SENP7" MicroRNA hsa-miR-873:PITA hsa-miR-873:PITA_TOP PITA 2.74E-30 1.54E-26 6.61E-30 6.09E-29 64 225 "NLGN4X,ZNF608,RTL9,FAM135A,MAP4K3,MARK4,ATP2B1,BCL7A,BMP7,CACNA1I,NOG,FOXN3,ACBD5,TM9SF4,MATR3,MYEF2,DMD,YAF2,EGR3,RGS17,PAN3,RTN3,MEX3B,TACC2,NPTN,OGA,FAXC,ARFIP1,AHDC1,PADI2,HRH3,ATXN2L,HNRNPK,KLC1,RSPO2,HNRNPM,NEUROD1,PCSK5,TMOD2,ZNF655,PLP1,FAT3,DPF2,PBRM1,ZNF532,KCNIP3,NLGN4Y,POGZ,LARP4,ELOVL4,KANK1,SULF2,SYN1,SYN2,PJA1,CAMTA1,SMG6,PSD3,TPM4,CADM1,USP1,ZIC2,CA10,CERS6" MicroRNA "GGCAGCT,MIR-22:MSigDB" "GGCAGCT,MIR-22:MSigDB" MSigDB 2.85E-30 1.60E-26 6.85E-30 6.31E-29 63 218 "EMILIN3,ADRA1B,PDZD4,BIN1,DPP10,USP37,ARRB1,WASF1,CABP7,KALRN,BRSK2,DGKI,FOXN3,ZFYVE9,DNAJB5,CSF1R,RIMS4,HDAC4,IP6K1,CTIF,SNAP91,SV2A,DSCAM,PHF20L1,EMX2,FAM49B,STAG2,MTHFD2,NR3C1,AGBL5,SMAP1,MAT2A,MBP,ADAM11,LDLRAD3,MIR4697HG,NFYA,NTRK2,KCNK10,PIK3CD,PPARA,SNRK,RAB5B,DPF2,RIC8B,FBXW7,RYR1,CHD9,SLC1A3,DHX30,SEPHS1,SLC9A5,EPC1,WDTC1,KDM3A,SATB2,ARHGEF12,SIRT1,ZFP91,HEY2,AMOT,CLDND1,MAP3K12" MicroRNA hsa-miR-23a*:mirSVR_highEffct hsa-miR-23a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.05E-30 1.71E-26 7.34E-30 6.76E-29 86 401 "ASIC2,ACLY,PLEKHH1,C1QTNF3,CNTNAP1,MARCH3,RASL11B,CCAR2,ATP1A2,BACH1,LINC00847,KSR1,CA4,ARHGEF2,CDC42,IGLON5,CNTN1,SMARCAL1,CLIP3,CSF2RA,MICAL2,ERC2,UBXN2A,NRSN1,TM9SF4,SIRPA,KIAA0753,SGSM2,EXOG,ECM2,EPHA5,FGF11,PSD2,NELFCD,CGREF1,OGA,HRASLS5,DISC1,PPARGC1A,GNAS,WDFY3-AS2,GPER1,AP4S1,PADI2,FRMD5,HNF4G,INSM1,KCNJ9,MBD1,MBNL1,MEIS1,KCTD6,SCAMP5,NTRK3,PDYN,PIK3C2A,PLXNB3,SLC26A11,WDR25,PYGM,PLEKHB2,FAT4,KHDRBS2,CCDC102B,KCNIP3,KCNIP1,RUFY2,SLC6A1,ZNF430,SLC9A5,SLC11A1,ATF7IP,RCOR3,PALLD,PDZRN3,SP2,JMJD6,SYN1,ENHO,TLR4,ERCC6L2,C5orf64,ZNF225,PCDH15,SLC17A7,WNK3" MicroRNA hsa-miR-18a-3p:Functional MTI Functional MTI miRTarbase 3.13E-30 1.76E-26 7.54E-30 6.94E-29 80 350 "DPF1,ACLY,ARID1A,TEX22,AP1B1,PPFIA1,CACHD1,SEMA4G,PRX,ATM,BCS1L,ARHGEF7,BSN,DIS3L,CLU,FADS2,NIPBL,TOGARAM2,CPS1,CRY2,CTIF,DBN1,YTHDC1,MED24,USP3,BSCL2,MRPL37,CD320,F3,SEC24B,FGF11,SEC23B,IP6K2,ATP2C1,CELF1,NEURL4,GART,KIAA1841,FAXC,SRCAP,GFER,TXNL4A,GNAS,GPD1,MFSD2A,FAM107A,GPR45,ATXN2L,ACOT7,HMGB1,AGFG1,LIMS1,MBD1,MDGA1,HNRNPM,PDE4A,CAMKV,PKM,KCTD15,PIGG,PTPRN,KLHL11,FNIP1,HSPA4L,ST6GAL1,KBTBD4,MAPKBP1,NCDN,STAC2,PHLDB1,EXOC7,WWC1,KIAA0930,PCDHGC5,WDR7,RPL7L1,UBTF,WNK1,ITM2C,RNF170" MicroRNA hsa-miR-196b:PITA hsa-miR-196b:PITA_TOP PITA 3.73E-30 2.10E-26 8.97E-30 8.27E-29 60 198 "USP31,PCDH19,DOC2A,LCORL,MAP4K3,GAS7,CASK,CHRD,CALM1,PTBP2,FAM19A5,PCYT1B,SLC4A7,TBPL1,RGS6,ATRNL1,PPP1R16B,PPP6R2,BLOC1S6,SNAP91,RASGRP1,MBNL2,EPB41L2,GALC,C15orf41,TOX3,CNTRL,DDX19B,SCRT2,LRRC4B,SYT9,LRP1B,RSPO2,NAP1L1,OPCML,PDGFRA,SCHIP1,MINDY2,RDX,ATP8B4,ATXN1,FNIP1,WDR37,SLC8A2,TRERF1,SOX11,PEG10,RBM26,RAP1GAP2,LARP4,MTCL1,ACSL6,PUM2,DICER1,NR2C2,TRPC3,TSC1,VSNL1,SOCS4,GAN" MicroRNA hsa-miR-196a:PITA hsa-miR-196a:PITA_TOP PITA 3.73E-30 2.10E-26 8.97E-30 8.27E-29 60 198 "USP31,PCDH19,DOC2A,LCORL,MAP4K3,GAS7,CASK,CHRD,CALM1,PTBP2,FAM19A5,PCYT1B,SLC4A7,TBPL1,RGS6,ATRNL1,PPP1R16B,PPP6R2,BLOC1S6,SNAP91,RASGRP1,MBNL2,EPB41L2,GALC,C15orf41,TOX3,CNTRL,DDX19B,SCRT2,LRRC4B,SYT9,LRP1B,RSPO2,NAP1L1,OPCML,PDGFRA,SCHIP1,MINDY2,RDX,ATP8B4,ATXN1,FNIP1,WDR37,SLC8A2,TRERF1,SOX11,PEG10,RBM26,RAP1GAP2,LARP4,MTCL1,ACSL6,PUM2,DICER1,NR2C2,TRPC3,TSC1,VSNL1,SOCS4,GAN" MicroRNA hsa-miR-181a*:mirSVR_lowEffct hsa-miR-181a*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.82E-30 2.15E-26 9.18E-30 8.45E-29 75 310 "GALNT13,SORCS2,ARHGAP20,MRTFA,CDC14B,TMEM263,ARHGDIA,ARNTL,BMP7,CABP7,CALM1,VSTM2A,MS4A7,COL9A2,GREB1,KCTD8,INTS1,DGKB,DGCR5,SRGAP3,EXOG,OLIG1,ABCC9,FRY,ABI2,SRARP,CORO2B,GORAB,AFF2,FLYWCH1,CELF1,TBR1,GABBR1,HBS1L,DISC1,GNAS,STON1,MCHR1,ADAMTS13,SMAP1,KCNA1,KCNN3,LIG4,SMAD1,ZFYVE27,NEFM,NF1,SLC11A2,RETREG2,TNPO2,MED1,CCDC144B,RIT2,RIC8B,ROBO2,SEC14L1,ST3GAL3,SLC1A7,SEPHS1,RAB3GAP1,CPEB4,CDK5RAP2,ANKRD36,JMJD6,TACC1,TAL1,SATB2,AZIN2,HHIP,SYNPO2,TRPC1,OSBP2,VLDLR,ACTR3B,FAM219B" MicroRNA hsa-miR-29c*:mirSVR_lowEffct hsa-miR-29c*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.50E-30 2.53E-26 1.08E-29 9.94E-29 65 234 "CPNE2,ADD1,SORCS1,SYT13,CACNA1D,CAPN3,KMT2C,SLC25A27,BTF3L4,CSF2RA,RIMS2,YTHDC1,MAGI2,SGSM2,DOCK2,FAM135B,PHC2,FAM13A,RGS17,ZNF589,KHDRBS3,CGREF1,KDM2B,ATF7,OPALIN,INSM1,KCNJ5,KCNMA1,KTN1,MAP4,MEIS2,PAK3,PCDH9,MAGEL2,PPP2R5C,NKAIN4,MASP1,SIDT1,PTAFR,PTPRB,NKAIN1,RASGRF2,EXD2,CCDC102B,NEK11,TNFRSF19,SEC14L1,ITSN1,PPM1E,SHANK2,CPEB4,ZNF423,SPTAN1,SEPT3,MLC1,MLST8,EXOC7,SATB2,CLASP1,WDR7,FAM189A1,AHCYL2,TPM1,USP1,PIANP" MicroRNA hsa-miR-373-3p:Functional MTI Functional MTI miRTarbase 4.77E-30 2.68E-26 1.15E-29 1.06E-28 100 531 "FZD9,SORCS2,ZNF578,TAOK1,MARCH4,KIF6,TMEM263,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,PRC1,ZBED1,DIS3L,CFL2,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,PHC2,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,ANKRD13B,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CSDC2,CRCP,CECR2,GRB10,MFSD2A,HAS2,ZHX1,HMGB1,JAK1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,GPSM2,SLC25A23,ZNF426,PRKACB,FITM2,SLC22A23,OCIAD1,RAD52,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,CDK19,STAC2,WWC1,SATB2,PSD3,GPRIN3,SIRT1,LEFTY2,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1,DPF3" MicroRNA hsa-miR-142-3p:PITA hsa-miR-142-3p:PITA_TOP PITA 5.08E-30 2.86E-26 1.22E-29 1.12E-28 60 199 "FMNL2,TAOK1,ANK3,APC,ARNTL,ZBTB10,ATP2A2,INA,ARHGEF2,CFL2,SOCS6,CLTA,HECTD1,RCHY1,SH2B1,CTNND1,PUM1,USP6NL,CPEB2,ACSL4,SUCO,AFF2,GAB1,GHR,EML4,KAT7,BACH2,HMGB1,C5orf24,ITGAV,MAP2,AFF1,GPR137C,PDE4B,STRN3,FAT3,ATG16L1,SCN2A,SCAF8,SGK1,FNDC3A,WDR37,SLC1A3,ATF7IP,SOX5,SOX11,TEX2,RAP1GAP2,TAB2,SS18,STAU1,PLCB1,SYPL1,TBL1X,ZMYND8,XPO1,ZIC3,SLC38A1,NAV3,PDSS2" MicroRNA hsa-miR-1911*:mirSVR_highEffct hsa-miR-1911*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.90E-30 3.31E-26 1.42E-29 1.30E-28 92 458 "ZNF608,ALCAM,ZNF687,AMPD3,AMT,MAGEE2,GPAM,IGDCC4,BCHE,KSR1,C5,CA8,CACNB2,KALRN,HIP1R,CCNH,P2RX6,CD81,PLEKHB1,QKI,ARMC8,CLIP3,ATRNL1,CFAP61,RUBCN,DTNA,PHC2,PHF20L1,EPHB1,ST3GAL6,TOMM40L,STRADA,MED12L,CAP2,DCTN2,ERGIC3,CELF1,ZMYND11,GALC,GATM,STARD3,GPD2,GPR12,PCLO,GRIK2,ZNF496,MAP4K5,FRMD3,HMGB1,BTBD17,ZNF546,ZNF678,KCNJ11,MAG,MAN2A2,MDM4,KCTD6,SNTG1,PBX1,A2ML1,MBOAT7,VPS13C,PTX3,RBBP6,ZYG11B,RGS4,TTLL7,ZFHX4,SUGCT,MCMBP,TCP11L1,TMEM156,AP1AR,SCN8A,TRIM46,NUBPL,KANSL3,RAB3GAP1,TNIK,ERBIN,STAU1,PHLDB1,NSFL1C,KLHL4,DMXL2,SYNE1,SLC44A1,TRPC3,FNDC5,CLHC1,PRTFDC1,CSDE1" MicroRNA hsa-miR-342-3p:Functional MTI Functional MTI miRTarbase 6.02E-30 3.38E-26 1.44E-29 1.33E-28 74 304 "KCTD16,BMP7,CANX,CRLF1,LETMD1,NCAN,PLXNA4,HDAC9,LONRF1,TM9SF4,EEF1A2,HIPK3,EGR3,ASB3,EPB41,WAC,POLR1B,GART,CBX1,GRID1,KIF3A,FAM107A,FRMD3,USP51,IDH3B,C2orf72,TJAP1,KCNK1,LSAMP,SHC3,PPM1L,MXI1,ZC3H12B,ZDHHC22,KCTD15,MTRF1L,STRN3,PSAT1,APTX,PTPRN2,FIGN,RFX3,RGS4,TMLHE,RPL15,HUNK,ATXN7,GALNT10,CPEB3,CHD9,ZNF430,SEPHS1,CPEB4,MAPKBP1,KIF13A,TRERF1,LHFPL4,ERC1,NFASC,TAB2,ZSCAN29,DNAJC9,SYT5,TACC1,TAL1,TIAM1,BHLHB9,RFTN2,ZNF610,UBE2H,UBTF,CRB2,ZDHHC20,NETO2" MicroRNA hsa-miR-4301:mirSVR_highEffct hsa-miR-4301:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.18E-30 3.47E-26 1.48E-29 1.36E-28 85 396 "CPNE2,ERMN,AP2A2,BCAR3,CNIH2,PPFIA1,CAPRIN2,ALDH7A1,DPY19L3,FUBP1,PRMT9,RUNX1T1,MAGI1,CFL2,SUMF2,ANKRD44,APPL1,GREB1,CTNND1,DDX46,RCAN1,DTNA,EFS,ZNF549,FER,POLR1B,FHL1,SGIP1,TPK1,ZNF605,STAG2,GABRA3,WASF3,CRCP,FERMT2,GRIA2,GRIN2C,GRM1,GRM7,AP4S1,HNMT,MSL1,C2orf72,JAK1,KCNC1,SMAD1,MBNL1,MIA2,CTNNA3,NDP,NFE2L2,PDE1C,XRN1,GPSM2,POLG,HYDIN,VPS13C,CNTLN,PTPRD,SLC6A15,FIGN,ELP2,CCDC102B,NEK11,MEG3,CCDC88A,SLC9A5,MAPKBP1,UNC80,USP33,NPAS3,ZNF302,NSFL1C,TBX15,ZFP90,METTL3,AMACR,SGK3,UGT8,PLEKHH2,ZNF45,EML6,PCDH15,KCNAB1,SLC4A10" MicroRNA hsa-miR-454-3p:Functional MTI Functional MTI miRTarbase 6.18E-30 3.47E-26 1.48E-29 1.36E-28 85 396 "ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,DAPK1,CEP170,SEC16A,MED12,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,MRPL37,ACSL4,DLC1,FKTN,POLR1B,SEC23B,FLNC,CINP,MSANTD4,SALL3,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PXK,PTPRG,RAB5B,UBR7,PTGR2,CLIP1,BTBD3,ATF7IP,TET1,KIF13A,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,SATB2,TCF7L2,SIK3,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,ZNF711,ZNF24,ZNF154,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-23b*:mirSVR_highEffct hsa-miR-23b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.51E-30 3.66E-26 1.56E-29 1.44E-28 86 405 "ASIC2,ACLY,PLEKHH1,ADRA1D,C1QTNF3,CNTNAP1,MARCH3,CCAR2,ATP1A2,BACH1,LINC00847,KSR1,CA4,ARHGEF2,CDC42,CNTN1,SMARCAL1,CLIP3,CSF2RA,MICAL2,ERC2,UBXN2A,NRSN1,ECE2,SIRPA,KIAA0753,SGSM2,EXOG,ECM2,EPHA5,ERBB2,CHST15,PSD2,NELFCD,CGREF1,OGA,HRASLS5,DISC1,PPARGC1A,GNAS,WDFY3-AS2,GPER1,KAT7,AP4S1,PADI2,FRMD5,ZNF678,INSM1,KCNJ9,MBD1,MBNL1,KCTD6,SCAMP5,NDUFA5,NTRK3,PDYN,PIK3C2A,PLXNB3,SLC26A11,WDR25,PYGM,PLEKHB2,FAT4,KHDRBS2,ZMAT4,KCNIP3,KCNIP1,RUFY2,SLC6A1,ZNF430,SLC9A5,SLC11A1,ATF7IP,RCOR3,PDZRN3,SP2,JMJD6,SYN1,ENHO,TLR4,ERCC6L2,C5orf64,ZNF225,HPS4,PCDH15,SLC17A7" MicroRNA hsa-miR-767-3p:PITA hsa-miR-767-3p:PITA_TOP PITA 6.96E-30 3.91E-26 1.67E-29 1.53E-28 62 214 "KCNH8,USP31,RTL9,SPOP,ALCAM,CNIH2,CHRD,ATP2B1,BCL2L2,THSD7A,DLGAP2,CNR1,ST18,DOCK4,TOX,DNAJC6,TIAM2,FBXL5,C2CD2L,GRIN3A,NR1D2,RBM12,EIF5,TMEM35A,CLVS1,PCYOX1,TACC2,STAU2,CECR2,PCLO,FAM19A2,MIER3,HTR2A,C5orf24,KCNA4,KIF2A,MAP2,SYT9,AFF1,MN1,PTOV1,NEFH,GPR85,MAPK9,SNRK,PTCH1,TMEM255A,SLC6A15,SCN8A,DOCK10,CPEB4,FAIM2,MYT1L,HECW1,LARP4,PRRC2C,SYT1,ANKRD28,CAMTA1,ARHGEF12,TNS2,POLR3H" MicroRNA hsa-miR-5698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.23E-30 4.06E-26 1.73E-29 1.59E-28 96 496 "ABCF1,CLK4,XKR4,ADCY2,RNF157,ESYT2,HACE1,SORCS2,TAOK1,ANK1,PPFIA3,PRX,DOCK11,CAMK2A,ISPD,METTL6,DLGAP3,TMEM184B,AKAP5,CRMP1,DBT,PLEKHM1,GNE,KRBA2,HEYL,OPTN,EFNA3,EIF4G1,TUBD1,ANKRD13B,WAC,SEC23B,AFF2,SPECC1,CELF1,MSANTD4,PRRC2B,CNDP1,KAT7,IBA57,KCNH2,LIMS1,GPR155,CHST6,MKLN1,NDUFA5,NEUROD2,NRGN,OLA1,ZNF655,CCSER2,PKM,GPSM2,SPATA6,PTPA,DIRAS2,BDNF-AS,ZYG11B,PRRT2,SETD5,MYH14,PGBD4,SNX22,UEVLD,EMID1,NCBP3,HSPA4L,PEX26,SMTN,PKNOX2,ANKRD36,FNBP1,ERC1,RAP1GAP2,NFASC,MAPK8IP3,MPRIP,KLHL7,ALG1,WWC1,VWC2,USP22,ZNF106,HHIP,THRA,RPRM,UBTF,MGAT5B,MEAF6,CLIP2,RICTOR,AGMO,ZNF74,ZNF154,TIGD6,RNF170" MicroRNA hsa-miR-616:PITA hsa-miR-616:PITA_TOP PITA 7.73E-30 4.34E-26 1.85E-29 1.70E-28 50 136 "ABHD6,ADD1,AXIN2,PTCHD1,TAOK1,TMEFF1,ZFYVE28,BSN,CHGB,PLCXD3,RIMS2,FAM131B,YTHDC1,CEP170,WDR20,EPB41L2,EPHB1,FAM49B,NPTN,ZNF512,GK,GPM6A,STON1,FAM19A2,ADAMTS6,BACH2,MIER3,SYNPO,MAT2A,MBNL1,MEIS1,NFIA,PDE4D,PMP22,MAPK10,CCDC112,SGK1,MYO18A,DZIP1,MYT1L,RBM26,SS18,ARHGEF9,PLCB1,TAC1,TRIM2,RPGRIP1L,TJP1,FNDC5,STMN4" MicroRNA hsa-miR-4768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.28E-30 4.65E-26 1.98E-29 1.82E-28 78 338 "RNF157,NLGN4X,SPOP,MARCH4,DGKD,USP37,ASCL1,PTCH2,ATP1A3,CABP7,CD86,CDH8,RAB3C,CST3,PITPNM3,ZSCAN23,MAML1,C2CD2L,EDN3,ELAVL3,EMX2,TUBB4A,CELF1,GABRA1,GALC,GATM,FAXC,SULT1C4,PCDH17,GJB1,GPR26,FRMD3,TLX1,NEGR1,IL6R,LSAMP,GPR155,CD200,MYBPC1,NFIX,NPTX1,P2RX7,GDAP1L1,PLCL1,PKIA,SNRK,PTPRN2,ZSCAN2,RDX,FIGN,ACER3,ATXN1,ATXN7,CPEB3,CHD9,SLC6A8,ZNF667,IGSF9B,ZNF415,RBM26,TROVE2,DIP2A,ANKRD28,EXOC7,MGRN1,HHIP,FBXL16,TNS1,TSC1,SGK3,ZNF23,DHX33,CADM2,PRDM10,NAV2,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-324-3p:Functional MTI Functional MTI miRTarbase 8.28E-30 4.65E-26 1.98E-29 1.82E-28 78 338 "ACLY,RBM10,ARID1A,AP2A1,PITPNM2,LRFN1,PPFIA1,STX16,SYNJ2,FUBP1,CACNA1I,MAGI1,FADS2,TOGARAM2,CPS1,APPL1,CTNND1,PUM1,YTHDC1,MED24,G3BP2,ARRDC4,EBI3,BSCL2,MRPL37,NSRP1,RACK1,SEC24B,SEC23B,PNMA2,KIAA1841,FAXC,SRCAP,KDM2B,GNAS,PRRC2B,MFSD2A,FAM107A,GPR45,ATXN2L,ACOT7,HMGB1,HSP90AA1,MAP4,MAT2A,MBD1,MDGA1,MYO6,KCNK10,ZDHHC8,CAMKV,PKM,CDIP1,PIGG,PLEKHB2,KLHL11,SBF1,ATXN1,FOXRED1,HSPA4L,CDK5RAP2,SON,CLUAP1,ARHGAP26,RBM26,POGZ,MPRIP,STAC2,GSE1,SUPT5H,PRRC2C,WWC1,KIAA0930,NACC2,TJP1,UBC,ZNF23,UBE3B" MicroRNA hsa-miR-6833-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.28E-30 4.65E-26 1.98E-29 1.82E-28 78 338 "RNF157,NLGN4X,SPOP,MARCH4,DGKD,USP37,ASCL1,PTCH2,ATP1A3,CABP7,CD86,CDH8,RAB3C,CST3,PITPNM3,ZSCAN23,MAML1,C2CD2L,EDN3,ELAVL3,EMX2,TUBB4A,CELF1,GABRA1,GALC,GATM,FAXC,SULT1C4,PCDH17,GJB1,GPR26,FRMD3,TLX1,NEGR1,IL6R,LSAMP,GPR155,CD200,MYBPC1,NFIX,NPTX1,P2RX7,GDAP1L1,PLCL1,PKIA,SNRK,PTPRN2,ZSCAN2,RDX,FIGN,ACER3,ATXN1,ATXN7,CPEB3,CHD9,SLC6A8,ZNF667,IGSF9B,ZNF415,RBM26,TROVE2,DIP2A,ANKRD28,EXOC7,MGRN1,HHIP,FBXL16,TNS1,TSC1,SGK3,ZNF23,DHX33,CADM2,PRDM10,NAV2,MPPE1,HNRNPA3,DPF3" MicroRNA hsa-miR-497-5p:Functional MTI Functional MTI miRTarbase 8.34E-30 4.69E-26 1.99E-29 1.83E-28 92 460 "AXIN2,FZD9,ADORA3,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,APP,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,BTRC,FOXK1,CA8,CANX,RUNX1T1,CCNT1,DLGAP3,CLU,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,DMPK,DMTF1,FCF1,HEYL,SIDT2,PLEKHA1,EN2,ZNF391,ANKMY1,ZNF585B,CAMSAP1,MSANTD4,NCKAP1,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,ARHGAP12,CHIC1,CCDC80,MYO5A,OCRL,PDE4D,ANLN,PIK3R1,PSAT1,PPP2R5C,PTPRD,PLEKHB2,RBBP6,ZFHX4,TMEM100,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,TCEA1,DICER1,ZMAT3,TGFBR3,TPM1,TPM2,TPM3,TUBB2A,UBE2H,AMOT,VAV2,WNT7A,ZBTB16,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-146a-5p:TargetScan hsa-miR-146a-5p TargetScan 9.02E-30 5.07E-26 2.15E-29 1.98E-28 59 194 "ESYT2,PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP2,QKI,CNTFR,ARMC8,FAM169A,APPL1,RIMS2,IST1,DGKG,DNAL1,CDON,RCAN1,EDNRB,HIPK3,HEYL,EIF4G2,ERBB4,RCSD1,CAMSAP1,CELF1,GPR75,KDM2B,GRID1,CELF3,IGSF1,KCND3,MAPT,MARK1,MMP16,LAYN,MYO5A,MYO6,MYT1,NOVA1,KCNK10,KCTD15,POU3F2,MED1,ERI2,RNASEL,ROBO1,ACER3,GALNT10,HSPA4L,KBTBD4,SCN3B,FAM208A,NSD1,FRYL,DDHD1,RFTN2,POLR3H" MicroRNA hsa-miR-146b-5p:TargetScan hsa-miR-146b-5p TargetScan 9.02E-30 5.07E-26 2.15E-29 1.98E-28 59 194 "ESYT2,PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP2,QKI,CNTFR,ARMC8,FAM169A,APPL1,RIMS2,IST1,DGKG,DNAL1,CDON,RCAN1,EDNRB,HIPK3,HEYL,EIF4G2,ERBB4,RCSD1,CAMSAP1,CELF1,GPR75,KDM2B,GRID1,CELF3,IGSF1,KCND3,MAPT,MARK1,MMP16,LAYN,MYO5A,MYO6,MYT1,NOVA1,KCNK10,KCTD15,POU3F2,MED1,ERI2,RNASEL,ROBO1,ACER3,GALNT10,HSPA4L,KBTBD4,SCN3B,FAM208A,NSD1,FRYL,DDHD1,RFTN2,POLR3H" MicroRNA hsa-miR-1248:PITA hsa-miR-1248:PITA_TOP PITA 1.02E-29 5.71E-26 2.42E-29 2.23E-28 65 237 "TMEM263,BCL2L2,JAZF1,LDLRAD4,CAMK2G,CD81,SOCS6,CLCN3,NIPBL,CSNK1G3,CNTNAP2,CTNND1,RIMS2,FGFR1OP2,GAPVD1,BRINP1,ELMSAN1,DLG2,CPEB2,PDCD6IP,FAM135B,ELAVL2,EML1,EPB41L1,ENPP6,EYA1,DLC1,AGAP3,PRELID3A,AHCYL1,PCDH17,ADAMTS6,KTN1,ADAM11,MEF2C,MYO5A,NOVA1,ZNF827,PDE1B,GPR85,NXPH1,MED1,PROX1,BSDC1,ZYG11B,RFX3,FBXW7,NCBP3,NLGN4Y,FAM214B,FAM126B,SOX11,HECW1,MYCBP2,SSTR1,ZSCAN29,PRRC2C,TBL1X,TIAM1,TRPS1,CADM1,TMEM237,NAV3,PDSS2,ST8SIA2" MicroRNA hsa-miR-379:mirSVR_highEffct hsa-miR-379:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.03E-29 5.81E-26 2.47E-29 2.27E-28 84 390 "SDE2,HECW2,OSBPL6,CC2D2A,LRRC7,OGT,PKP4,CAPRIN2,TMEM108,ATP1A2,ZNF582,MTMR2,MAGI1,CNOT8,FAM149A,IGDCC3,DOCK4,C8orf34,RABGAP1L,DPP6,ABI1,E2F6,EDN1,FRY,EIF4G2,ETV1,PIPOX,CACNG3,UBE2E3,SLC37A3,GABRB1,GALNT15,PCDH17,RAB30,STARD3,FUT10,RAPGEF4,GRM8,LINC01551,MAP4K5,HMGB1,SMAP1,IDH3A,GAREM2,IL6ST,NME9,KCNK2,KIF5A,VWA5A,KCTD6,ERICH3,MRPL42,MSR1,DNHD1,SMIM11A,OXTR,MTRF1L,MINDY2,PTK2,PEX5,NUDT11,RNASEL,MRAP2,LRRK2,HSPA4L,FNDC3A,SLITRK3,ZNF365,SLC1A3,CCDC88A,TEX2,CDK19,TTBK2,SYPL1,MMS19,SEMA4A,ADGRL3,BEX4,MTCH1,MEAF6,SYNC,EMSY,ADAMTS9,TRAM2-AS1" MicroRNA hsa-miR-1257:PITA hsa-miR-1257:PITA_TOP PITA 1.06E-29 5.93E-26 2.52E-29 2.32E-28 57 181 "ARID1A,ERMN,UNC5A,GPAM,CADPS,DACT3,CANX,SPAG9,USP6,DLGAP2,FOXN3,NRXN3,CLTC,QKI,BTF3L4,CREM,TENM4,ST18,FRMPD4,DNAJC6,SMG7,FAM13A,PAN3,CACNG3,MSTN,RND1,CIT,SMAP1,ZIC5,KCNA1,IPO5,SFXN5,MXI1,MYO6,PCMT1,PIK3C2A,PTPRD,FAM120C,DPF2,REV3L,SEMA6D,CSRNP3,PPM1E,CPEB3,NLGN1,CCDC88A,PDZD2,MYCBP2,LMO3,POGZ,SEPT8,DMXL2,CBX5,TBC1D15,WIPF1,EMSY,HNRNPA3" MicroRNA hsa-miR-371a-5p:TargetScan hsa-miR-371a-5p TargetScan 1.08E-29 6.06E-26 2.57E-29 2.37E-28 70 275 "RNF150,HACE1,PKP4,ATP1A2,ATP2B2,FOXK1,PTBP2,CAMK2G,KRIT1,C1orf52,CFL2,DLGAP3,COL9A1,BTF3L4,AATK,CCDC144A,DGKG,SCRN1,DNAL1,FAM107B,DLG4,DNAH9,FARSB,GOLGA7,CALCRL,RCAN2,ETV1,RTN3,CELF1,PCDH17,MALT1,GPR75,PRRC2B,GPD2,KAT7,BVES,SCRG1,NEGR1,MMP16,MN1,CTNNA3,MYCN,NEUROD1,NOVA2,PAH,PAK3,PBX1,PCDH8,FTO,EPN1,APTX,GTDC1,RPS6KA2,CSRNP3,SCN2A,R3HDM2,PKNOX2,CPEB4,KDM3A,MYCBP2,CLSTN2,GSE1,NECAB1,GPRIN3,FRRS1L,ANKS1B,CADM2,HNRNPA3,MSRB3,NETO1" MicroRNA "TCCAGAG,MIR-518C:MSigDB" "TCCAGAG,MIR-518C:MSigDB" MSigDB 1.15E-29 6.45E-26 2.73E-29 2.52E-28 51 143 "PCDH19,ANK2,PRX,PCDHGB4,ATP2A2,CAMK2G,CDC42,NRXN2,TMEM184B,NCOR2,PUM1,GOLGA7,TNK2,MED12L,GAD1,ZMYND11,MSTN,RND1,TCERG1,BACH2,MEIS2,MKLN1,NFIX,PCDHGC3,PCDH9,SDK2,ING3,SEPT4,CCDC144B,GTDC1,SMPD3,CUX2,RPGRIP1L,TCF12,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RICTOR,SLC30A4,PARP6,ST8SIA2" MicroRNA hsa-miR-24:PITA hsa-miR-24:PITA_TOP PITA 1.19E-29 6.66E-26 2.82E-29 2.60E-28 63 223 "ADCY6,LRFN2,TAOK1,OGT,APBB2,ATP2B1,BCL2L2,RHBDL1,MAGI1,CNTFR,SNCAIP,RIMS2,RUBCN,MATR3,KLHL3,DLG2,SLC12A6,FAM78B,APH1A,EGR3,KCNMB2,SCML2,DLC1,FCGRT,AMOTL2,AFF2,GAP43,SESN1,SPIN1,MCHR1,TMEM121B,RNF165,USP54,SCRT2,INPP5B,KCNK2,SFXN5,CHIC1,MEIS2,GIT1,MXI1,NEFM,NEUROD1,NEUROD2,NPTX1,PTPRD,RAB5B,GTDC1,RAVER2,TNFRSF19,WDTC1,POGZ,NEK4,SYP,SEMA4A,SMG6,ACSL6,SZT2,TIAM1,MTMR14,FAM155A,MEIS3,ZXDA" MicroRNA hsa-miR-4300:mirSVR_highEffct hsa-miR-4300:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-29 6.75E-26 2.86E-29 2.63E-28 88 426 "CCDC85A,SLC44A5,ADGRF5,LRFN1,PPFIA4,ARHGEF25,CBR1,NIPBL,COL9A2,CREM,NCOR1,SEC24C,RUBCN,CCDC144A,CNIH3,RHOBTB1,CHRDL1,GPR61,C8orf37,SRRM1,NRN1,ATP8A1,ZMYND15,FOLR2,HVCN1,DISC1,KIAA1841,PRLHR,SERP2,GRM7,GUCY1B1,GPR45,USP54,ZNF678,KCNK3,STXBP5,NCOA7,ASPRV1,CHIC1,CNOT4,NUCB2,NUMA1,GPR88,PDE3A,PDE4D,ZNF655,A2ML1,PLP1,MTRF1L,PPP2R2B,SLC6A15,RFX4,RGR,RNASEL,CARF,NEK11,PEAR1,COPZ1,BTBD3,SPHKAP,TET1,GKAP1,SORCS3,NMNAT2,SPART,ATP10B,LARP4,ADHFE1,VAMP1,POPDC3,DMXL2,HIF3A,AP4E1,THRA,MTMR14,C9orf85,ZNF384,METTL3,GORASP1,CLDND1,SLC17A7,WNK3,EPM2A,DOCK8,KAT6A,CAMK1G,IFT88,NETO2" MicroRNA hsa-miR-30b-3p:Functional MTI Functional MTI miRTarbase 1.62E-29 9.09E-26 3.85E-29 3.54E-28 113 667 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,RNPS1,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,CXXC4,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA hsa-miR-4789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-29 1.05E-25 4.44E-29 4.09E-28 72 293 "ADCYAP1R1,TAOK1,STX16,ATP2A2,BACH1,CA8,TBRG4,B4GALT6,COL9A1,BAG4,ANKRD44,PLXNA4,SPOCK2,MED24,CPEB2,EGR3,CERCAM,TUBD1,ACSL4,TUBA1B,SYNCRIP,FLT1,SGIP1,ZBED3,MPP6,GCK,MMADHC,PPARGC1A,COPS8,GLI2,PARD3B,HLF,C5orf24,SCIN,KCNA4,KLHL23,KCNK1,KIF5C,SYTL4,ZNF827,TMOD2,PIK3R1,PURG,SNRK,SH3TC2,NCBP3,CSRNP3,RAB3GAP1,SLC22A4,ZFP1,SNCB,ZNF415,WDTC1,AJAP1,NSFL1C,SIK3,HHIP,SLC44A1,BHLHB9,BEX4,RGMB,NR2C2,ZNF610,UBE2H,UGT8,NDRG4,SLC30A4,MFF,LRP8,ADAMTS9,MVB12B,FAM198A" MicroRNA hsa-miR-92b-3p:Functional MTI Functional MTI miRTarbase 1.87E-29 1.05E-25 4.44E-29 4.09E-28 117 709 "ABR,RBM10,SLC12A5,GRAMD1B,AP2A2,AP1B1,CASKIN1,FAM135A,USP28,ZSCAN18,ATP2A2,DOCK11,CDK5R1,SYNJ1,CDC27,FOXN3,CLTA,TMEM184B,HECTD1,APPL1,EDRF1,PHF19,EARS2,SPOCK2,GIT2,DBT,HP1BP3,POM121,G3BP2,CPEB2,MRO,KMT5B,PLEKHA1,EIF1,DENND4A,DNAJC27,PRMT5,KIAA1109,CAMSAP1,MEX3B,SLC37A3,NPTN,DKK3,GAA,BRD8,GLYR1,KIAA1958,PRRC2B,FUT10,LILRA2,TPPP,CIT,HMGCR,AGBL5,EID2B,C5orf24,ZIC5,RBPJ,IL6ST,ITGAV,LAMP2,PIK3AP1,MBNL1,SESN3,MYO5A,CNOT4,PFKFB4,PIK3CD,CCSER2,SNX10,ZFYVE21,XRN1,PURG,TNPO2,TATDN3,UHRF1BP1,MTMR10,REV3L,SLC25A36,SETD5,TCP11L1,ATXN1,FNIP1,SFPQ,CPEB3,ZNF430,ATF7IP,CPEB4,SMARCC2,FAM126B,SOX11,KDM3A,UNC5B,KIF1B,MCF2L2,PBLD,ITPRID2,SUPT5H,MMS19,TACC1,DOCK9,NACC2,RBFOX2,TRIO,TSC1,SGK3,ZNF17,ZNF24,PMEPA1,MFF,CSDE1,EVI5,XKR7,RNF103,PHTF2,FXR1,GAN" MicroRNA "CTCAGGG,MIR-125A:MSigDB" "CTCAGGG,MIR-125A:MSigDB" MSigDB 1.88E-29 1.06E-25 4.46E-29 4.11E-28 73 301 "ABR,ASIC1,ABHD6,ADD2,LRFN2,MTUS1,USP37,MADD,SLC4A4,ADGRB1,MTMR3,NIPA1,BSN,DIRAS1,SCARB1,DNAJB5,ZNF385A,ENTPD4,NCOR2,FAM131B,PHYHIP,IST1,IP6K1,ELMSAN1,DCTN1,ABCC5,PHC2,CNNM1,SEMA4D,BRPF3,GGT7,GRB10,ATOH8,MAN1B1,LIFR,MAP6,ADAM11,MEIS2,MSI1,MYT1,RETREG2,DRAM2,PPP2R5C,MASP1,DPF2,RET,EMID1,ATXN1,SCN2B,CASC3,CPEB3,MYO18A,ST6GAL1,SLC8A2,ABTB1,SOX11,SPTB,IQSEC2,SYN2,SATB2,DICER1,AP4E1,TRPS1,SLC35A4,KLC2,CRB2,CSDE1,XKR7,SLC17A7,GOPC,VANGL2,SOCS4,SLC4A10" MicroRNA "CTCAGGG,MIR-125B:MSigDB" "CTCAGGG,MIR-125B:MSigDB" MSigDB 1.88E-29 1.06E-25 4.46E-29 4.11E-28 73 301 "ABR,ASIC1,ABHD6,ADD2,LRFN2,MTUS1,USP37,MADD,SLC4A4,ADGRB1,MTMR3,NIPA1,BSN,DIRAS1,SCARB1,DNAJB5,ZNF385A,ENTPD4,NCOR2,FAM131B,PHYHIP,IST1,IP6K1,ELMSAN1,DCTN1,ABCC5,PHC2,CNNM1,SEMA4D,BRPF3,GGT7,GRB10,ATOH8,MAN1B1,LIFR,MAP6,ADAM11,MEIS2,MSI1,MYT1,RETREG2,DRAM2,PPP2R5C,MASP1,DPF2,RET,EMID1,ATXN1,SCN2B,CASC3,CPEB3,MYO18A,ST6GAL1,SLC8A2,ABTB1,SOX11,SPTB,IQSEC2,SYN2,SATB2,DICER1,AP4E1,TRPS1,SLC35A4,KLC2,CRB2,CSDE1,XKR7,SLC17A7,GOPC,VANGL2,SOCS4,SLC4A10" MicroRNA hsa-miR-27a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-29 1.16E-25 4.89E-29 4.50E-28 88 429 "SLC25A25,ADAR,ADD1,FZD9,TAOK1,SEMA6A,SEMA7A,APBB2,APC,GPAM,ARNTL,ZBTB10,RNF182,DPY19L3,CDC27,SOCS6,KMT2C,CNN3,PNKD,RGS6,CTNND1,LONRF1,LIN54,ELMO1,C2CD2L,SEC16A,NR1D2,ATN1,PHC2,FEM1B,EGFR,KMT5B,EIF5,EN2,DNAJC27,TOMM40L,GTF2IRD2,AMOTL2,SUCO,FAM49B,CELF1,OGA,CAB39,ZNF638,GPT2,NUDT21,MIER3,HMGCR,IGF1,DIPK1A,SLC6A17,LAMP2,LIFR,MKLN1,MYO9A,MYT1,NF1,NFE2L2,OLR1,RETREG2,BDNF-AS,ALG9,FBXW7,RXRA,SEMA6D,COPZ1,FNDC3A,SLC6A8,CPEB4,ZFP1,WDTC1,SP4,ERC1,PEG10,TROVE2,MPRIP,STAU1,GSE1,NSD1,FRYL,TGFBR3,ZNF106,ZNF384,TTC3,WNK1,CAB39L,AP3B2,SPATA13" MicroRNA hsa-miR-1273h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-29 1.21E-25 5.13E-29 4.72E-28 112 659 "XKR4,ADAR,ADCY5,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA "ATACCTC,MIR-202:MSigDB" "ATACCTC,MIR-202:MSigDB" MSigDB 2.19E-29 1.23E-25 5.19E-29 4.78E-28 55 170 "XKR4,PCDH19,ZBTB10,BCL7A,DST,CACNA1E,FOXN3,CHN2,NDST3,ARMC8,MYRIP,CREM,SEC24C,KIAA0040,ZC3H11A,SRGAP3,CPEB2,DUSP9,EFNB3,ELAVL3,STARD3NL,DLC1,IP6K2,GAD1,GHR,PPARGC1A,RNF165,HAS2,SMAP1,LAMP2,HECTD2,MYCN,NAP1L1,XRN1,PURG,LRRN3,LAMA1,ATG16L1,CPEB3,SHANK2,CPEB4,SOX11,HECW1,KIF1B,TAB2,SYT1,KIAA0930,DICER1,CSMD1,RBFOX2,SLC30A4,ADAMTS9,SNX27,KAT6A,VANGL2" MicroRNA hsa-miR-220c:PITA hsa-miR-220c:PITA_TOP PITA 2.30E-29 1.29E-25 5.46E-29 5.03E-28 60 204 "ASIC2,ARID1A,SLITRK1,LRRC7,CDC14B,SEMA4G,ATP2A2,CACNA1A,CAMK2G,CFL2,SOCS6,CRY2,NCOR2,CHD5,SLITRK5,PUM1,PHYHIP,HP1BP3,RUSC2,NR1D2,CPEB2,EDIL3,APH1A,PAN3,AGAP3,GAP43,CPLX2,GJB1,GNAO1,ADAMTS6,MIER3,C5orf24,ARHGAP12,CHIC1,PABPC1L2A,NOVA2,PBX1,PCSK2,PLP1,PTCH1,PEX5,PLEKHB2,RBBP6,RIC8B,ZFHX4,FAM19A1,SCG5,PPM1E,RIMS1,SNAP25,SOX5,ZHX3,POGZ,SS18,ARHGEF9,FBXW11,AHCYL2,PMEPA1,MAP3K12,KAT6A" MicroRNA hsa-miR-933:mirSVR_lowEffct hsa-miR-933:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.37E-29 1.33E-25 5.62E-29 5.18E-28 82 377 "PWWP2A,PTCHD1,AP2A2,CC2D2A,PLA2G6,ZNF687,PDZD4,AMPD2,APAF1,GPAM,CDK10,ZFYVE28,ARNTL,ATP2B3,BBS2,BCL2L2,CBLN1,CBR1,P2RX6,SLC22A6,ARHGEF6,COL11A2,ABI3BP,TBPL1,PDE4DIP,GREB1,ECE2,SPOCK3,SLC29A4,F3,ARFGAP2,TBR1,TVP23A,STAG2,GNAS,PCLO,GRIK2,GRIN2D,GRM2,AGBL5,RAB41,AQP11,XRRA1,HNRNPM,NINJ2,CNOT4,OCRL,A2ML1,FAM216A,PRKACB,MAPK4,BCAS3,ARID4A,RNF220,ZFHX4,YY1AP1,PCMTD2,ST6GALNAC6,FAM102A,WDR37,PEX26,RAB3GAP1,SHANK2,SMARCD3,IGSF9B,KIF1B,ATP10B,ARHGEF9,TAC3,TIAM1,ZFP91,TMOD1,PIK3R5,C9orf85,FNDC5,FAM155A,PLPPR2,UBE3B,FBXO36,NUP214,JMJD1C,PIANP" MicroRNA hsa-miR-1914:mirSVR_highEffct hsa-miR-1914:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.90E-29 1.63E-25 6.87E-29 6.33E-28 90 449 "NDRG3,ADCY6,DPY19L2P4,ABCD2,AMPD3,OGT,LCORL,RGS20,LINC00173,CAPRIN2,ZBTB10,CACNB4,CARS,CCKBR,ENTPD6,CNGA3,CNR1,ENTPD4,CS,RIMS2,ST18,BOC,DCAF8,FRMPD4,ECM2,E2F5,AASS,EMX2,EPS8,PIPOX,FGFR1,AMOTL2,ATP2C1,TRAF3IP2,GAD2,ERAP1,GHR,HPGDS,KIAA1958,CECR2,GRIA2,GRM7,KLF12,DOCK7,INPP5B,KCNN2,MAN2A2,MAOB,MDM4,ZNF680,ZNF92,PABPC1L2A,NCAM1,NELL2,SNTG1,PAK3,PCDH8,DUSP26,PLXNB3,RELN,PSMD13,ZMAT4,GTDC1,CCDC82,KLHDC8A,GSTCD,LRRK2,ATXN7,ITSN1,ST6GAL1,SLC1A3,RUFY2,SLC6A1,ZNF430,SEPHS1,BTBD7,MYO16,SATB2,SLC19A3,AP4E1,ANKRD24,TPM3,SGK3,PITPNB,NPDC1,ZNF138,UPF3A,PRDM2,KAT6A,SMIM8" MicroRNA hsa-miR-4779:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.92E-29 1.64E-25 6.90E-29 6.36E-28 71 287 "DPF1,XKR4,ADD2,MTUS1,SORCS2,TRMT9B,PHF12,SEMA4G,ARRB1,CANX,CACNA2D2,TMEM184B,KIAA0513,PLEKHM1,SEC16A,CHRDL1,TNK2,EN2,EPB41L1,MTSS1L,KATNAL1,AMOTL2,BRSK1,GJB1,CRCP,GLYR1,GRIN2D,ZBTB49,HMX1,SHISA6,NKD1,STMN1,PPM1L,MPP2,SAMD14,NBL1,ZC3H12B,NDUFA5,NELL2,NOVA2,OGDH,PDE4A,FTO,TNPO2,POLR2F,PPARA,PPP2R2B,TMEM231,IQSEC3,ALG9,HES6,SLC6A1,TRIM67,SLIT1,KIF21B,UNC5B,CAMTA2,FAM168A,ASTN2,HHIP,NACC2,ASXL3,TPM3,BCL2L13,INTS3,URM1,NAV2,ITM2C,PARP11,ACTR3B,SSPN" MicroRNA hsa-let-7e*:mirSVR_lowEffct hsa-let-7e*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.92E-29 1.64E-25 6.91E-29 6.36E-28 67 256 "RALGAPA1,ZNF608,ANK3,CACHD1,MIR9-3HG,DST,NAE1,ISPD,PRC1,B4GALT6,ZFP28,SLC35F1,ATRNL1,CEP170,CASP8AP2,DNAJB6,ABCC5,DNM1L,EDNRA,EGFR,EYA1,ARMCX1,ABCA8,SH3YL1,CORO2B,ANKFY1,FOLH1,TRMO,GABRA5,IQGAP2,GATM,ZNF638,PCLO,GRB10,GRIA2,ELOVL5,CFAP126,LRRCC1,INSM1,METTL21A,MDM4,MOBP,MYO9A,NEK1,NOVA1,LRIT2,KCTD15,KANSL1,PRKACB,GRAMD1C,ZSCAN2,UBR7,ACER3,ATAT1,SATB1,PPM1E,HKDC1,FNDC3A,TBL1X,ATMIN,KCNE5,VIPR2,GUSBP1,XRCC4,ZNF24,DPYSL5,ZNF248" MicroRNA hsa-miR-3924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-29 1.66E-25 6.98E-29 6.43E-28 65 241 "TMEM132B,ZNF608,HACE1,PCDH10,APP,CCDC74A,BACH1,CA12,SLC24A2,KIAA0408,DOCK4,MYADM,DCAF8,SV2B,YAF2,MBNL2,ABI2,CERCAM,SCML2,ZBED3,FYN,GABRG1,GCK,SESN1,BVES,C5orf24,ZIC5,DOCK7,IL6ST,KCNJ3,KLHL23,KCNK1,L1CAM,MDM4,MKLN1,MMP16,NCAM2,NELL2,NFIA,OPCML,PIK3R1,PLP1,PPP1R1A,PROX1,CNNM2,PTPRD,RAB5B,RIC8B,PGBD4,CSRNP3,BTBD3,SEPHS1,SLC8A1,SOX5,PRRC2C,SYPL1,TMEM178B,TBCEL,AHCYL2,HHIP,BEX4,CSMD1,MAP3K12,ADAMTS9,NETO2" MicroRNA hsa-miR-376b:PITA hsa-miR-376b:PITA_TOP PITA 3.10E-29 1.74E-25 7.32E-29 6.74E-28 60 205 "DSCAML1,NLGN4X,OSBPL8,PITPNM2,ARHGAP5,SLC4A4,ATP2A2,ATP2B1,DCAF5,SLC25A14,SEPT7,QKI,NIPBL,SLC4A7,CSNK1G3,FAM131B,COPS7A,SRGAP3,WDR20,ARNT2,GRIN3A,SIDT2,EML1,EN2,KHDRBS3,PCDH17,FERMT2,GRIK2,GRIK5,HCN1,PDE4B,LRP12,MED1,ELOVL2,SLC6A15,ROBO1,SALL1,PPM1E,SHC4,CHD9,FBXO11,SLC6A1,TET1,MBD5,CDK19,ITPRID2,LARP4,SYT4,CUX2,TIAM1,TJP1,WIPF1,ZIC3,CELF4,SCG2,NAV3,PPP1R3F,SLC17A6,PAK5,SLC4A10" MicroRNA hsa-miR-376a:PITA hsa-miR-376a:PITA_TOP PITA 3.10E-29 1.74E-25 7.32E-29 6.74E-28 60 205 "DSCAML1,NLGN4X,OSBPL8,PITPNM2,ARHGAP5,SLC4A4,ATP2A2,ATP2B1,DCAF5,SLC25A14,SEPT7,QKI,NIPBL,SLC4A7,CSNK1G3,FAM131B,COPS7A,SRGAP3,WDR20,ARNT2,GRIN3A,SIDT2,EML1,EN2,KHDRBS3,PCDH17,FERMT2,GRIK2,GRIK5,HCN1,PDE4B,LRP12,MED1,ELOVL2,SLC6A15,ROBO1,SALL1,PPM1E,SHC4,CHD9,FBXO11,SLC6A1,TET1,MBD5,CDK19,ITPRID2,LARP4,SYT4,CUX2,TIAM1,TJP1,WIPF1,ZIC3,CELF4,SCG2,NAV3,PPP1R3F,SLC17A6,PAK5,SLC4A10" MicroRNA hsa-miR-205:PITA hsa-miR-205:PITA_TOP PITA 3.58E-29 2.01E-25 8.45E-29 7.79E-28 70 280 "PTCHD1,HACE1,PI16,TMEM263,NCOA1,SLC4A4,CANX,CFL2,CHN1,B4GALT6,CLTC,QKI,ELMSAN1,MAGI2,SMG7,DLG2,CPEB2,PHC2,CNNM1,RBM12,ABI2,CALCRL,EPB41,EPB41L1,ERBB4,RTN3,ACSL4,SORBS1,ST6GALNAC3,PHYHIPL,JPH4,GPM6A,GRIA4,KLF12,SYT9,CHIC1,KITLG,HCN1,TBC1D25,CLDN11,PDE3B,MED1,TMEM260,OCIAD1,LRRK2,HUNK,CLIP1,CPEB3,MAGI3,BTBD3,TET1,CXXC4,KDM4B,SP4,CDK19,SS18,PLCB1,CAMSAP2,WWC1,MGRN1,SATB2,CUX2,TP53BP2,RBFOX2,TRPS1,CADM1,FAM155A,AMOT,ADAMTS9,SNX27" MicroRNA hsa-let-7c-5p:Functional MTI Functional MTI miRTarbase 4.00E-29 2.24E-25 9.43E-29 8.68E-28 97 516 "FZD9,MTUS1,ZNF578,CDC42BPA,MAP4K3,CACHD1,AQP6,IGDCC4,NUMB,ATP2A2,BACH1,FMNL3,QKI,TMEM184B,ARMC8,CREM,CRY2,IP6K1,DNAL1,DNAJC6,MTX3,DNAH9,E2F5,E2F6,EDN1,ANKRD46,EIF4G2,EN2,PLEKHO1,TUBB4A,TOMM40L,FOXO3,TRMO,PDLIM5,CELF1,DOT1L,SALL3,DISC1,GATM,SRCAP,COPS8,POLL,FUT10,NUDT21,RABL2A,C5orf24,HES5,IL6R,KPNA5,NAT8L,CHST6,MDM4,MEF2C,THYN1,MYO9A,NAP1L1,NME4,NPTX1,SLC11A2,NUCB2,OPRL1,PPP2R5E,CNNM2,PTK2,QDPR,RAB5B,USP47,BSDC1,RDX,FIGN,SAFB,ATXN2,KIF27,FNDC3A,R3HDM2,SLC12A2,PEG10,KIF1B,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,DICER1,SIRT1,TGFBR3,CBX5,BHLHB9,RBFOX2,TUBB2A,SLC35A4,RICTOR,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-4323:mirSVR_highEffct hsa-miR-4323:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.14E-29 2.32E-25 9.76E-29 8.99E-28 86 415 "ADD1,SORCS1,PPFIA1,SUGT1P4-STRA6LP-CCDC180,MAGEE2,AQP6,KSR1,NAE1,DDR1,CAMK2G,LARGE1,MAGI1,TMEM155,CSF1R,PDE4DIP,FAM169A,SLITRK5,CMTM5,CTH,RIMS2,ST18,USP6NL,C2CD2L,SLC25A18,PHC2,RASGRP1,ELAVL4,VPS13B,TLR7,ECSIT,SH3YL1,SCML2,FGFR1,ATP13A4,ATP2C1,GAD1,NEU3,TNRC6A,INSM2,STON1,GRIA1,GRIA2,GRM7,HPS5,NKD1,SYT9,MEIS1,AFDN,ERICH3,FXYD6,CHAMP1,PCDH9,NALCN,PLIN1,RELN,TMEM260,PTPRB,PRRT2,GTDC1,RNF220,RORB,DGLUCY,HOGA1,KBTBD4,EPC1,SNRPN,UHRF1BP1L,KDM4C,TAB2,ATP10B,ZSCAN29,SEPT8,ADAMTS17,COBL,CAMTA1,ANO4,OBSL1,TPM2,RPL7L1,UBTF,FLRT2,PRDM2,CIAPIN1,PCDH15,EPM2A,FBXO36" MicroRNA hsa-miR-1178:PITA hsa-miR-1178:PITA_TOP PITA 4.29E-29 2.41E-25 1.01E-28 9.33E-28 55 172 "RTL9,API5,BSN,SPAG9,ZNF385A,CLOCK,CRY2,DOCK4,C2CD2L,MAGI2,G3BP2,GRIN3A,NR1D2,CPEB2,EGR3,EIF5,NCALD,NRN1,PSD2,TACC2,NPTN,STAU2,GABRA5,GLS,GPM6A,NUDT21,TMEM121B,PCLO,MIER3,MARK1,MAT2A,SYT9,MOBP,NFIA,HCN1,GPR85,POU3F2,MED1,PPP3CB,MAPK9,ZMAT4,RIC8B,ATXN1,SNCA,SON,HECW1,TNS2,RIMBP2,TPM3,PMEPA1,EVI5,NAV3,PAK5,HNRNPA3,MSRB3" MicroRNA hsa-miR-361-3p:mirSVR_highEffct hsa-miR-361-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.38E-29 2.46E-25 1.03E-28 9.51E-28 78 346 "PWWP2A,AP2A1,FAM135A,OGT,CCAR2,DCAF5,BLM,DDR1,PTBP2,CAMK2B,ENTPD6,ZBED5,TPP1,DNAJB5,TOMM20,DLX1,HS3ST4,DMPK,ABI1,FAM135B,KLHL5,EFNB3,TMEM132E,TMEM35A,EPB41,POMT1,DLL3,JPH4,TMEM8B,GNAS,ZBTB49,WIF1,RASSF8,KCNA2,KCNJ4,KCNK1,KCNMA1,KIF5C,PIK3AP1,MAOB,MRPL42,MSR1,NCAM1,PCDH9,PDE1C,PDE1B,PLP1,RC3H2,LRP12,POU3F2,MED1,USP47,SLC6A15,PRRT2,MORC4,CARF,PNMA8A,MEG3,SH3GL3,NUBPL,SLC1A6,SLC6A9,YPEL4,SLC12A4,IFT122,TSPYL2,AJAP1,NAT16,AP4E1,TGFBR3,TJP1,ZNF384,UBE2H,UGT8,TRIM9,EMSY,HPS4,NHSL1" MicroRNA "GTGCAAT,MIR-32:MSigDB" "GTGCAAT,MIR-32:MSigDB" MSigDB 4.64E-29 2.61E-25 1.09E-28 1.01E-27 71 289 "CSMD3,DSCAML1,SLC12A5,FAM135A,OGT,DPP10,USP28,DDX3Y,ATP2A2,HCN2,SYNJ1,CACNA1I,BSN,KALRN,CDH10,DLGAP2,TMEM184B,SLC32A1,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,FOXG1,TACC2,IQGAP2,GAP43,GLYR1,PCDH11X,ITGAV,PIK3AP1,MARK1,SESN3,P2RY13,NFIA,NFIX,NOVA1,NPTX1,KCNK10,NOMO2,CEP41,PTPRO,BSDC1,REV3L,RGS3,ROBO2,FBXW7,SYNDIG1,SCN3A,FAM19A1,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,HHIP,TRIO,TSC1,FMN2,SLC17A6,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-367:MSigDB" "GTGCAAT,MIR-367:MSigDB" MSigDB 4.64E-29 2.61E-25 1.09E-28 1.01E-27 71 289 "CSMD3,DSCAML1,SLC12A5,FAM135A,OGT,DPP10,USP28,DDX3Y,ATP2A2,HCN2,SYNJ1,CACNA1I,BSN,KALRN,CDH10,DLGAP2,TMEM184B,SLC32A1,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,FOXG1,TACC2,IQGAP2,GAP43,GLYR1,PCDH11X,ITGAV,PIK3AP1,MARK1,SESN3,P2RY13,NFIA,NFIX,NOVA1,NPTX1,KCNK10,NOMO2,CEP41,PTPRO,BSDC1,REV3L,RGS3,ROBO2,FBXW7,SYNDIG1,SCN3A,FAM19A1,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,HHIP,TRIO,TSC1,FMN2,SLC17A6,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-25:MSigDB" "GTGCAAT,MIR-25:MSigDB" MSigDB 4.64E-29 2.61E-25 1.09E-28 1.01E-27 71 289 "CSMD3,DSCAML1,SLC12A5,FAM135A,OGT,DPP10,USP28,DDX3Y,ATP2A2,HCN2,SYNJ1,CACNA1I,BSN,KALRN,CDH10,DLGAP2,TMEM184B,SLC32A1,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,FOXG1,TACC2,IQGAP2,GAP43,GLYR1,PCDH11X,ITGAV,PIK3AP1,MARK1,SESN3,P2RY13,NFIA,NFIX,NOVA1,NPTX1,KCNK10,NOMO2,CEP41,PTPRO,BSDC1,REV3L,RGS3,ROBO2,FBXW7,SYNDIG1,SCN3A,FAM19A1,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,HHIP,TRIO,TSC1,FMN2,SLC17A6,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-363:MSigDB" "GTGCAAT,MIR-363:MSigDB" MSigDB 4.64E-29 2.61E-25 1.09E-28 1.01E-27 71 289 "CSMD3,DSCAML1,SLC12A5,FAM135A,OGT,DPP10,USP28,DDX3Y,ATP2A2,HCN2,SYNJ1,CACNA1I,BSN,KALRN,CDH10,DLGAP2,TMEM184B,SLC32A1,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,FOXG1,TACC2,IQGAP2,GAP43,GLYR1,PCDH11X,ITGAV,PIK3AP1,MARK1,SESN3,P2RY13,NFIA,NFIX,NOVA1,NPTX1,KCNK10,NOMO2,CEP41,PTPRO,BSDC1,REV3L,RGS3,ROBO2,FBXW7,SYNDIG1,SCN3A,FAM19A1,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,HHIP,TRIO,TSC1,FMN2,SLC17A6,PHTF2,ADAMTSL3,FXR1" MicroRNA "GTGCAAT,MIR-92:MSigDB" "GTGCAAT,MIR-92:MSigDB" MSigDB 4.64E-29 2.61E-25 1.09E-28 1.01E-27 71 289 "CSMD3,DSCAML1,SLC12A5,FAM135A,OGT,DPP10,USP28,DDX3Y,ATP2A2,HCN2,SYNJ1,CACNA1I,BSN,KALRN,CDH10,DLGAP2,TMEM184B,SLC32A1,SOCS5,PITPNC1,CPEB2,ARRDC4,FRY,KMT5B,PLEKHA1,RGS17,POLK,FOXG1,TACC2,IQGAP2,GAP43,GLYR1,PCDH11X,ITGAV,PIK3AP1,MARK1,SESN3,P2RY13,NFIA,NFIX,NOVA1,NPTX1,KCNK10,NOMO2,CEP41,PTPRO,BSDC1,REV3L,RGS3,ROBO2,FBXW7,SYNDIG1,SCN3A,FAM19A1,CPEB3,MYO18A,CPEB4,SOX11,MYCBP2,ITPRID2,ELOVL4,SYN2,DOCK9,HHIP,TRIO,TSC1,FMN2,SLC17A6,PHTF2,ADAMTSL3,FXR1" MicroRNA hsa-miR-638:mirSVR_lowEffct hsa-miR-638:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.70E-29 2.64E-25 1.11E-28 1.02E-27 84 398 "ADD1,ADORA2A,ALS2,LGR5,CAPRIN2,ATP2B1,RNF182,ADAM15,CFLAR,LINC00906,MMD2,KCNAB3,NOG,UBE2L6,CPNE6,IGLON5,CNTFR,PNKD,RBM39,ANKRD44,DCAF4,ARHGAP24,JAKMIP2,EXOG,SLC29A4,DNM2,FARSB,FCF1,APH1A,EGR3,ELAVL4,DCTN4,FGF11,CGREF1,TVP23A,BRPF3,GAP43,GLS,NUDT21,CLASRP,AP4S1,MIER3,HLF,KIF5A,MEIS2,SRSF12,FXYD7,CNOT4,PCDH18,MAPKAP1,PRKAB2,RAB3IL1,USP47,PRRT2,RGS7,ZFHX4,RERGL,ATAT1,CCDC92,ZFP1,INTS9,RCOR3,CLUAP1,KDM4C,CDK19,NFASC,SSPO,PJA1,CAMTA1,MLST8,HIF3A,RNF175,HEY2,TNFRSF1B,NUTM2A,CCDC136,LMF1,ZIC3,ZNF711,MICU3,FMN2,INTS3,DNAH10,NUP214" MicroRNA hsa-miR-665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.72E-29 2.65E-25 1.11E-28 1.02E-27 119 737 "ABCF1,AS3MT,NDRG3,SLC24A4,HACE1,TXNDC16,TRMT9B,APAF1,AQP6,CDC14B,SFMBT2,ATM,ZNF583,ZNF555,CBS,MTMR7,SLC16A4,EVI5L,CCPG1,SOCS6,NDST3,NRXN3,SUMF2,ACBD5,MFSD4A,SLC35F1,IPCEF1,PYGO1,MYADM,KIAA0513,TMEM170A,ELMSAN1,PLEKHM1,HP1BP3,SGSM2,MTX3,DNAH9,SLC29A4,DNM2,SYT15,HEYL,TMTC1,MRO,RASA4,IRAK4,ELAVL2,MRNIP,VPS26C,ANKMY1,ZNF585B,ZNF589,FOXO3,ATP13A4,MSANTD4,SESN1,CRCP,GPR75,GLUL,ZNF638,GNG3,GNG4,KIF3A,BVES,AGBL5,IGF1,DOCK7,KLHL23,SMAD9,MATN3,SHC3,PPM1L,MPP2,SLC11A2,NRGN,NUCB1,TNPO2,FAT3,PPP2R2B,NCR3LG1,MTMR10,TMEM145,QDPR,CEP97,PLEKHB2,MSANTD2,RGS12,GSTCD,PTGR2,NCBP3,SLC30A10,SH3BP2,MAGI3,SLC2A5,SLC6A1,PKNOX2,SEPHS1,ATF7IP,KIF21B,CDK19,MCF2L2,LHPP,ZSCAN29,ACSBG1,FAM208A,SLC19A3,AKNA,PCDHA6,AHCYL2,ARL10,TMEM9,TPM3,FRRS1L,USP1,LAT2,ZNF17,INTS3,DNALI1,EVI5,SNX27" MicroRNA hsa-miR-873-5p.1:TargetScan hsa-miR-873-5p.1 TargetScan 5.22E-29 2.93E-25 1.23E-28 1.13E-27 68 266 "ABAT,HECW2,ALAD,APC,APP,MARK4,ATP2B1,BCL7A,BMP7,CACNA1I,CBFA2T2,DLGAP3,NRXN3,DNAJB5,COL9A2,GPRASP1,FRMPD4,MATR3,JAKMIP2,PLEKHM1,MYEF2,ABI2,RGS17,RTN3,HPCAL4,JKAMP,NPTN,GABRB1,ERAP1,FAXC,GOLGB1,PADI2,HMGCR,HNRNPK,PPM1L,MN1,SAMD14,HNRNPM,CLDN11,PCSK5,PDE4D,MED1,GDPD1,PIGG,RASGRF1,DPF2,KLHL11,MCMBP,HUNK,KCNIP3,FAM192A,PRCD,HSPA4L,EPC1,SCN3B,C3orf70,ALG1,PSD3,DAAM2,CADM1,EML6,DNALI1,GDPD5,HNRNPA3,CERS6,PIANP,FXR1,NETO1" MicroRNA hsa-miR-1256:PITA hsa-miR-1256:PITA_TOP PITA 5.28E-29 2.97E-25 1.24E-28 1.14E-27 51 147 "PCDH19,LRRC7,ALCAM,OGT,DPP10,CNTNAP1,CAPRIN2,BCL7A,SYNJ1,CPNE6,CNR1,CNTFR,CTNND2,FRMPD4,HDAC4,SRGAP3,E2F5,EIF1,EYA1,CAB39,RFFL,NR3C1,FRMD3,AGFG1,ZIC5,MAT2A,NEXMIF,ZC3H12B,NFIX,PCDH9,PDGFRA,PDZRN4,TMEM255A,RGS7,NUDT11,RXRA,SALL1,SGK1,SMARCE1,KDM4B,TAB2,STAC2,SYNE2,ANKRD28,DMXL2,NR2E1,CSMD1,TUB,FLRT2,HNRNPA3,PHTF2" MicroRNA hsa-miR-323-5p:mirSVR_highEffct hsa-miR-323-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.43E-29 3.05E-25 1.27E-28 1.17E-27 83 390 "DGCR6,ABCF1,ADD2,PLEKHH1,CC2D2A,LTBP4,DGKD,ATP1B3,ATP2B1,ALDH7A1,NOL4,TTLL9,BBS2,CBFA2T2,SEPT7,CDH8,NRXN3,PPT2,NIPBL,IGLON5,CNR1,SLC4A8,SMARCAL1,KIF26A,PITPNC1,RHOBTB1,USP3,DPH1,WDPCP,PHC2,KMT5B,DCTN4,VPS13B,SEZ6,EPHA5,ANKRD13B,FOXF2,FYB1,GLRB,GPM6B,CIT,MIER3,ELOVL5,KCNK2,MAOB,MEIS1,MMP16,CCDC80,NELL1,SNTG1,PDPK1,KANSL1,WBP1L,ENOX1,RBBP6,PNMA8A,ROBO1,ABCA11P,ATAT1,ZNF331,SGK1,FERMT1,NLGN1,FAM81A,SNRPN,TAB2,CLASP2,ZSCAN29,RGL1,SEMA4A,DMXL2,PCDHB4,CRB1,THRA,MTMR14,TK2,TNR,PIK3R5,C9orf85,TRO,SLC13A3,SSPN,PRRT4" MicroRNA hsa-miR-103a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 5.78E-29 3.24E-25 1.36E-28 1.25E-27 90 453 "SYS1,AXIN2,ADORA3,AP2A1,SEMA6A,OGT,STK33,ZBTB10,NUMB,DOCK11,DST,SYNJ1,MTMR3,CA12,RUNX1T1,CCNT1,TBPL1,OSBPL3,CSNK1G3,VCAN,PPP1R16B,PHF19,RIMS3,TMEM170A,DAPK1,YTHDC1,JAKMIP2,G3BP2,DMPK,CPEB2,DMTF1,GOLT1B,FCF1,YAF2,PLEKHA1,EN2,KATNAL1,ZNF585B,CAMSAP1,ANKFY1,CAMKK2,GABRB1,CAB39,GPD1,EML4,ZHX1,AGFG1,IDH3A,KIF5A,LAMP2,MAP4,MDM4,ZNF680,MYBPC1,MYCN,MYO5A,NFIA,PDE4D,ENPP2,PIK3R1,PPP2R5C,PRKAB2,CNNM2,TMEM255A,RBBP6,EXD2,TMEM100,FBXW7,CLIP1,SALL1,CPEB3,SLC6A9,EPC1,SMARCE1,TMCC1,SON,DNAJC9,CYB561A3,DICER1,TGFBR3,NACC2,TJP1,TPD52,SLC35A4,AMOT,ZBTB38,DHX33,ITM2C,PLSCR4,GOPC" MicroRNA hsa-miR-3689c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.51E-29 3.65E-25 1.53E-28 1.40E-27 111 657 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA hsa-miR-3689a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.51E-29 3.65E-25 1.53E-28 1.40E-27 111 657 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA hsa-miR-3689b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.51E-29 3.65E-25 1.53E-28 1.40E-27 111 657 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA hsa-miR-1468-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.66E-29 3.74E-25 1.56E-28 1.44E-27 68 267 "ADARB2,SPOP,FAM135A,CDC42BPA,STX16,DST,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,KIAA0513,DBN1,SPATA2,G3BP2,TMTC1,RCAN2,TAOK3,MED12L,CAMSAP1,ZMYND11,MALT1,RAB30,FUT10,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,PSAT1,PPP2R5E,PRKACB,MAPK8,NWD1,KLHL11,RAVER2,SGK1,PEX26,SLC6A8,KIF13A,SPART,POGZ,DIP2A,ARC,SYPL1,DICER1,ZMAT3,TLR4,TUBB2A,RPL7L1,ZNF24,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-4278:mirSVR_highEffct hsa-miR-4278:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.97E-29 3.91E-25 1.63E-28 1.50E-27 74 315 "ABCF1,ASIC2,GALNT16,WDR35,DISP3,KIF6,USP28,CHID1,SLC2A11,ALDH7A1,C5,CAPN3,DGKI,DCLK1,SRSF11,CHN1,SLC25A27,TRIM69,KATNAL2,DCAF8,ELMSAN1,PHF20L1,ABI2,TNK2,EPHB1,EFS,AGAP3,ABLIM2,TRAF3IP2,TTBK1,RND1,DBF4,INSM2,ATP2B1-AS1,GRIA1,RBPJ,USP54,MOBP,MXI1,NDUFA5,NELL1,STRN3,EPB41L4B,RANBP3L,VPS13C,RLBP1,TCP11L1,FAM182A,CSRNP3,LINC00461,FBXO11,SLC1A3,INAVA,DOP1A,LMO3,RGL1,FGD4,SUPT5H,SYNE2,SYT4,ITGB3BP,ELP5,STXBP4,BEST1,VSNL1,SF1,KCNT2,MKRN3,SYNC,PRDM2,PCBP4,MVB12B,LAS1L,JPH3" MicroRNA "CCTGTGA,MIR-513:MSigDB" "CCTGTGA,MIR-513:MSigDB" MSigDB 7.03E-29 3.95E-25 1.64E-28 1.51E-27 46 118 "ACHE,ADD3,MTUS1,OGT,CDC14B,PRX,PDXK,RUNX1T1,QKI,CRY2,CNTNAP2,PPP1R16B,CTNND1,SRGAP3,DMPK,DPYSL2,ELAVL2,EYA1,FGFR1,BAIAP2,AGAP2,AGAP3,EVL,USP21,TBR1,FREM1,PPARGC1A,C1QL4,MAP4K5,KCND3,NTRK2,MAPK7,TMEM260,SH3GL3,PPM1E,NPAS3,ARHGEF9,SYP,SZT2,TIE1,NSD2,RICTOR,CA10,MAP3K12,NAV2,KAT6A" MicroRNA hsa-miR-146b-3p:mirSVR_highEffct hsa-miR-146b-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.85E-29 4.41E-25 1.84E-28 1.69E-27 91 464 "NCKAP5,PTCHD1,ANXA7,DGKD,ALS2,DYNLL1,STX16,TTLL9,MTMR2,KALRN,CAMK2G,ISPD,PLEKHB1,CASC2,CPS1,SNCAIP,NRSN1,FRMPD4,COPS7A,GSDME,DYNC1I1,DNM1L,YAF2,SUGP2,TUBD1,KCNMB2,GORAB,ATP13A4,SGIP1,JKAMP,GABRG2,GALC,GK,GPR12,GRIK2,AP4S1,SCIN,IL6ST,KCNJ9,MAT2A,AQP11,MBNL1,LDLRAD3,LRP1B,MEF2C,AFDN,MMP16,SESN3,NF1,NRCAM,DDR2,NUCB2,IGSF11,PAK3,CYTL1,TMIE,PPP1R1A,TMEM260,ZSCAN2,CEP97,OXR1,RFX4,RGS4,CARF,GSTCD,LRFN5,TNFRSF19,COPZ1,NTNG1,PAAF1,ZNF365,PPP4R3A,CPEB4,RIMS1,SON,SEPT8,ADHFE1,PLCB1,ADGRL3,HIF3A,TF,SLC44A1,RUNDC3B,TMEFF2,OSBP2,WRN,ETNPPL,SMARCAD1,UPF3A,NAV2,PAK5" MicroRNA hsa-miR-301b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 8.59E-29 4.82E-25 2.01E-28 1.85E-27 81 375 "ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,DAPK1,CEP170,SEC16A,DPYSL2,EDN1,TMTC1,EGFR,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,SALL3,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PXK,PTPRG,RAB5B,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,SATB2,TCF7L2,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,ZNF711,ZNF24,ZBTB16,ZNF154,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-4290:mirSVR_highEffct hsa-miR-4290:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.11E-29 5.12E-25 2.13E-28 1.96E-27 82 384 "VWA5B2,SERPINA3,PTCHD1,BCAS1,NUMB,ATP1A2,CFLAR,C5,CAMK2G,CERS5,CD86,LOC730101,LARGE1,IGFN1,LSMEM2,ZFYVE9,PICK1,PHACTR3,FRMPD4,KIAA0586,IP6K1,KIAA0319,DDX46,NYAP1,PHF20L1,EGR3,PLEKHA1,ADGRV1,NSRP1,FER,CAMSAP1,CAP2,MEGF10,GABRB1,SESN1,COPS8,OS9,STMN2,AP4S1,GPR45,SYNPO,OPALIN,IDH3B,SYT9,MDM4,LRP1B,MEF2C,MYO9A,NELL1,CNTN3,CAMKV,ZNF655,A2ML1,PLXNB3,PPP3CB,TMEM260,NKAIN1,ACSS3,ZCWPW1,SLC6A15,RPE,NEK11,SCN8A,ASAP3,USP33,ZCCHC24,KDM4C,ZNF423,SEPT3,VPS13A,PLCB1,TACC1,CAMTA1,UNC5D,ZEB1,TPM2,PRMT8,HEPACAM,CAB39L,C12orf4,PIANP,JPH3" MicroRNA hsa-miR-6780a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.73E-29 5.47E-25 2.27E-28 2.10E-27 111 660 "XKR4,ADAR,PLEKHH1,TXNDC16,TRMT9B,PHF12,AQP6,DNAH17,ASPA,TTLL9,SYNJ2,FOXK1,ISPD,SLC16A4,MYOM2,LONRF2,CDR1,SUMF2,BTF3L4,MFSD4A,CRY2,NCOR2,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,TOMM20,IP6K1,DNAL1,SPATA2,SLC29A4,PHC2,TMTC1,MRO,ABI2,RASA4,PLEKHA1,MRNIP,IGSF6,ANKFY1,TRMO,PNMA2,KBTBD12,TRAF3IP2,DISC1,AHDC1,CRCP,TNRC6A,GLUL,GNG4,KAT7,BVES,IRAK3,MIER3,SCRG1,AGBL5,ZNF491,IGF1,DOCK7,TJAP1,IBA57,SMAD9,MAT2A,MATN3,PPM1L,NBL1,SLC11A2,ZNF713,PDGFRA,BEST3,PFKFB3,FTO,FAT3,KANSL1,MTMR10,QDPR,RAB5B,CEP97,PLEKHB2,IQSEC3,KLHDC8A,PGBD4,FNIP1,HES6,SOX6,MYO18A,CLSTN1,SLC1A2,ZKSCAN3,ZCCHC24,MCF2L2,ZSCAN29,FAM208A,TPCN2,SLC19A3,ARL10,ERCC6L2,SSBP2,RFTN2,RPL7L1,KLC2,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,CIAPIN1,SNX27,TMEM63C" MicroRNA "GTCTTCC,MIR-7:MSigDB" "GTCTTCC,MIR-7:MSigDB" MSigDB 9.90E-29 5.56E-25 2.31E-28 2.13E-27 52 155 "CSMD3,OGT,PPFIA3,SLC4A4,ATP2B2,DIRAS1,FOXN3,CNOT8,CNN3,CRY2,BOC,SPATA2,G3BP2,DYRK1A,EGR3,ERBB4,ACSL4,HPCAL4,ANKFY1,GABBR1,KLF12,MAP4,ADAM11,SCAMP5,CHAMP1,PAX6,PDE4D,PIK3CD,CCSER2,PLEC,MAPKAP1,STRN3,PRKCB,MAPK4,PTK2,OXR1,ARID4A,SEMA6D,SATB1,ATXN1,SCN2B,AMBRA1,WDR47,SLC6A9,SLC8A3,SHANK2,CLASP2,ANKRD12,TCF12,LRRC8A,FLRT2,GAL3ST3" MicroRNA hsa-miR-4459:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-28 5.65E-25 2.35E-28 2.16E-27 114 691 "ABCF1,ADD2,SLC24A4,CASKIN1,HACE1,TXNDC16,SMIM17,PHF12,APAF1,PDXK,ASPH,ATM,ZNF583,BTRC,FOXK1,DDR1,ISPD,CBS,MYOM2,EVI5L,CDR1,CACNA2D2,JAM2,NDST3,NRXN3,ACBD5,NCOR2,SUSD5,CTH,USP6NL,MYADM,GAPVD1,KIAA0513,RASSF2,LONRF1,TMEM170A,ELMSAN1,HP1BP3,MTX3,DNAH9,DNM2,MRO,ZNF549,ANKMY1,ZNF585B,KBTBD12,NCKAP1,MTHFD2,SESN1,GPR75,GLUL,LUZP2,GNAS,GNG4,LILRA2,KIF3A,ZBTB49,RABL2A,ATOH8,AGBL5,SHISA6,IGF1,KCNJ5,KIF5A,STMN1,CHST6,MDM4,PPM1L,MMP17,MPP2,SFR1,NFIX,NUCB1,ZNF713,PIK3CD,CCSER2,PLEC,PACSIN1,TNPO2,FAT3,PPARA,PPP2R2B,NCR3LG1,MTMR10,ZNF844,RAB5B,CEP97,RBBP8,MSANTD2,RGS12,PTGR2,FNIP1,SLC30A10,STUM,MAGI3,PREX2,SLC2A5,ATF7IP,KIF21B,FNBP1,MCF2L2,NEK4,ACSBG1,PSD3,AHCYL2,HIF3A,TPM3,SSBP2,RFTN2,ZNF610,LAT2,ZNF17,ZFAND5,INTS3" MicroRNA hsa-miR-660-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-28 5.85E-25 2.43E-28 2.24E-27 81 376 "RNF157,ADD1,SLC4A4,ATP2B3,GPR146,NIPA1,RAB3C,SLC22A6,STOML1,IGLON5,RTTN,LRIG1,PDE4DIP,DBN1,ZBTB24,RUSC2,C2CD2L,RABGAP1L,RASA4,RGS17,TUBD1,TMEM132C,CHST15,FKTN,NCKAP1,PCDH17,GJB1,KIAA1958,CNDP1,GPR26,GRID1,NR3C1,GRM1,GPR45,HMGB1,SCRG1,TLX1,ZDHHC15,C2CD4C,METTL21A,KCNJ11,VWA5A,LSAMP,GPR155,MAT2A,AFF1,MOG,SAMD5,JAKMIP3,ALDH1L2,HMGCLL1,MTRF1L,KANSL1,FITM2,APTX,PTAFR,ZSCAN2,GTDC1,CYB561D1,RXRA,STX1B,PEX26,SLIT1,BDP1,TMEM178B,FAM208A,ALG1,AGTPBP1,LEFTY2,ZNF106,ARL10,PARD3,SSBP2,RPL7L1,LAT2,DPYSL5,ZNF195,LMAN2L,SIGLEC10,FAM13C,RNF170" MicroRNA hsa-miR-30d-5p:Functional MTI Functional MTI miRTarbase 1.18E-28 6.63E-25 2.75E-28 2.53E-27 80 368 "CDC7,TAOK1,SEMA6A,MARCH4,PCDH10,USP37,ATM,ATP1A1,STX16,ATP2A2,DPY19L3,ST3GAL5,MAP4K4,SLC4A7,TBPL1,BAG4,PREPL,CREM,EDRF1,COPS7A,SACS,FEM1B,CELSR3,MRO,ASB3,DCTN4,EPB41,SCML2,CHST15,FKTN,FOXG1,CELF1,MSANTD4,HHIPL1,GAB1,IP6K3,MTHFD2,DBF4,TNRC6A,EML4,MIER3,ELOVL5,JAK1,LIFR,LIMS1,SMAD1,LYPLAL1,MTR,NAP1L1,OPHN1,PPP3CB,MAPK8,UHRF1BP1,REV3L,SEC61A2,RNF220,PBRM1,SETD5,ALG9,PCMTD2,SBF1,FNIP1,PPP4R3A,BTBD7,CPEB4,KDM3A,SP4,PEG10,STAU1,ZSCAN29,AZIN2,SLC35G2,NACC2,ZMYND8,XPO1,MKRN3,POLR3H,ZFAND5,PHTF2,ZDHHC20" MicroRNA hsa-miR-193a-3p:PITA hsa-miR-193a-3p:PITA_TOP PITA 1.20E-28 6.74E-25 2.80E-28 2.58E-27 50 143 "KCNH8,UPRT,STX16,BCL2L2,CALB1,CALM1,RUNX1T1,KIAA1549L,CTNND2,FAM131B,ZC3H11A,DYRK1A,RBM12,EN2,ETV1,FGF1,ANKFY1,ST6GALNAC3,BRPF3,GNAO1,KIT,CAMK2N2,STMN1,MYCN,NEXMIF,NOVA1,PCSK2,CAMKV,CCSER2,PPP2R5C,MSANTD2,ATXN1,CLSTN1,YPEL4,SLC20A2,ZHX3,HECW1,ERBIN,ST5,CAMTA1,AGTPBP1,TCF4,DMXL2,ARHGEF12,LRRC8A,R3HDM1,CADM1,ZIC3,NAV3,RNF146" MicroRNA hsa-miR-1911:mirSVR_highEffct hsa-miR-1911:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.45E-28 8.17E-25 3.39E-28 3.12E-27 71 294 "CSMD3,GALNT13,AP2A2,CC2D2A,ALCAM,UNC79,LCORL,ASPH,SEC11C,CAST,METTL6,CDC27,B4GALT6,CNR1,COL4A5,AKAP12,CYBB,HDAC9,ZNF804A,GSDME,RHOBTB1,PLPPR4,SV2B,ABCC9,RABEPK,NSRP1,DLC1,SMC2,DACH2,HRASLS5,GABRB1,IQGAP2,GRIA4,GRIK4,MAEL,NXPH2,GPR45,MIER3,VSIG4,LINC00667,KCNN2,SYTL4,MEF2C,NUCB2,PAK3,PPP2R5E,RPRD1A,CARF,ATP8B4,LRRK2,SLC30A10,SH3BGR,CHD9,CNKSR2,DZIP1,ZNF365,SON,KDM3A,ENKUR,DBNDD2,SRPK2,TAB2,TCF12,FRYL,THRA,RIMBP2,FNDC5,EMSY,KCNAB1,MPPE1,FZD3" MicroRNA hsa-miR-1182:PITA hsa-miR-1182:PITA_TOP PITA 1.68E-28 9.44E-25 3.91E-28 3.61E-27 46 120 "KCNH8,ASIC1,SYS1,ARID1A,PCDH19,API5,CACNA2D1,CAMK2G,DCLK1,SEC24C,ERC2,FRMPD4,SRGAP3,DMTN,KCNMB2,TAOK3,USP21,PCDH11X,RNF165,ADAMTS6,CELF3,ZHX1,KLF12,NKD1,ZIC5,MEF2C,OLA1,CDK14,PPP3CB,KANSL1,MAPK10,RELN,RBBP6,RGS4,STX1B,SST,SYP,SYPL1,ANO4,KAT6B,EIF4ENIF1,MKRN3,SLC38A1,WNK3,KAT6A,ADAMTS10" MicroRNA hsa-miR-1265:PITA hsa-miR-1265:PITA_TOP PITA 1.98E-28 1.11E-24 4.62E-28 4.25E-27 54 170 "ABAT,ASIC1,XKR4,NCOA1,ATP2B1,KMT2C,TMEM155,NRG2,TENM4,RIMS4,CNTNAP2,FRMPD4,ELMSAN1,CPEB2,DPYSL2,ATN1,EMX2,ADAMTS6,KLF12,MIER3,ZIC5,BRINP3,KCNMA1,ADAM11,SHC3,MYCN,NF1,NOVA1,PDE3A,GPR85,PMP22,PPP2R5E,KANSL1,CNNM2,SNX22,NCBP3,ITSN1,SH3GL3,CHD9,NLGN1,CPEB4,SOX5,ERC1,CLASP2,LARP4,LRRC4,STXBP1,PLCB1,SYT1,WSCD1,FRYL,TPM3,FLRT2,GOPC" MicroRNA hsa-miR-3613-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-28 1.27E-24 5.24E-28 4.83E-27 95 508 "PTCHD1,SLC24A4,EIF4G3,ZNF582,CANX,MAP7,CD38,CFL2,GPR37L1,HECTD1,BTF3L4,TBPL1,HINFP,ATRNL1,PHF14,USP6NL,RASSF2,TMEM170A,ELMSAN1,HEPH,FBXO25,GUCD1,SGSM2,MTX3,DLG4,HIPK3,FCF1,TMTC1,CERCAM,C8orf37,ZNF549,FGF12,SPECC1,CELF1,WASF3,MALT1,FUT10,NUDT21,GRB10,RFFL,BVES,FRMD3,ZNF678,KCNB1,KCNN3,ARHGAP12,DBNL,SESN3,CTNNA3,NFYA,CNOT4,IGSF11,OLR1,PAK3,PDE3A,GPR85,PDZRN4,SLC36A4,FAT3,MAPK8,GDPD1,BSDC1,KLHL11,KLHDC8A,GSTCD,ZNF568,NCBP3,TRA2B,SH3BP2,PPP4R3A,BTBD3,SLC14A1,IGSF9B,KIF13A,FAM126B,FNBP1,UHRF1BP1L,POGZ,MPRIP,ADAMTS17,TCF7L2,CLASP1,DICER1,ZMAT3,HHIP,KCTD2,TUBB2A,UBE3A,ZNF28,NDRG4,ADAMTS9,KCNAB1,WIPF2,WNK3,DPF3" MicroRNA "TGTGTGA,MIR-377:MSigDB" "TGTGTGA,MIR-377:MSigDB" MSigDB 2.37E-28 1.33E-24 5.50E-28 5.07E-27 56 184 "ARID1A,PCDH10,NT5C3B,MIER1,PRX,MADD,MARCH3,NCOA1,RNF182,JAZF1,CACNA2D2,FOXN3,QKI,ARMC8,PUM1,HDAC9,DNAJC6,C2CD2L,CDON,EDNRB,DMTN,CAP2,FLNC,NBEA,GLYR1,CCDC184,RNF165,ATXN2L,NEGR1,KCNMA1,IPO5,CAMK2N2,MMP16,NKX2-2,SLC11A2,PRTG,PDGFRA,GPR85,LRP12,PTPRN,ZDHHC14,RET,ATXN1,ATXN7,SLC6A8,NAPB,BTBD7,CPEB4,SRPK2,ITPRID2,PLCB1,CAMTA1,RPGRIP1L,AMACR,NSD2,RICTOR" MicroRNA hsa-miR-1278:PITA hsa-miR-1278:PITA_TOP PITA 2.37E-28 1.33E-24 5.50E-28 5.07E-27 56 184 "KLHL13,TAOK1,PITPNM2,PPFIA4,EIF4G3,DPY19L3,RUNX1T1,TMEM257,KIAA1549L,SH2B1,ST18,KIAA0408,MYEF2,G3BP2,DYRK1A,EDIL3,ST8SIA3,YAF2,ELN,GPHN,EYA1,FOXO3,TACC2,FUT9,ATP8A2,RNPS1,PRRC2B,GRIA2,GUCY1A1,AGFG1,LRRTM3,KCNA1,IPO5,MAP4,MN1,NAP1L3,NEFM,OLA1,SCHIP1,TTC13,ZNF532,ROBO1,RTN1,SEMA6D,DOCK10,PKNOX2,SMARCA4,ERBIN,PRRC2C,SYT4,TCF12,HHIP,AKTIP,TBC1D15,GOPC,TIGD6" MicroRNA "CATGTAA,MIR-496:MSigDB" "CATGTAA,MIR-496:MSigDB" MSigDB 2.41E-28 1.35E-24 5.59E-28 5.15E-27 53 164 "KCNH8,ESYT2,HACE1,SEMA6A,DPP10,ASCL1,DDX3Y,DPY19L3,BACH1,NIPA1,CANX,LDB2,B4GALT6,QKI,LRIG1,CNTNAP2,SLITRK5,PHF14,TOX,DMD,YAF2,OLFM1,NBEA,KHDRBS3,NSG2,GRIA2,BACH2,LAMP2,HECTD2,MAP2,MAT2A,MEF2C,MEIS2,NEUROD1,PDE3A,PURG,NXPH1,LRRN3,MAPK9,PTHLH,RNF220,SLC25A36,ROBO1,ZNF331,SEMA6D,CPEB4,MYT1L,CLASP2,CAMTA1,SATB2,ZIC1,PRDM10,NAV3" MicroRNA hsa-miR-485-5p:Non-Functional MTI (Weak) Non-Functional MTI (Weak) miRTarbase 2.53E-28 1.42E-24 5.89E-28 5.43E-27 100 557 "ABCF1,AS3MT,NDRG3,PNMA8B,SLC24A4,TXNDC16,CEP126,KIF6,LRFN1,CDC42BPA,AQP6,ARHGDIA,ATM,ZNF583,SYNJ2,CCNT1,SLC16A4,NRXN3,CLU,SUMF2,MFSD4A,SLC35F1,CRY2,IPCEF1,RIMS4,UBXN2A,KIAA0408,MYADM,KIAA0513,TMEM170A,ELMSAN1,DNAH9,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,ZNF589,ATP13A4,DOT1L,PPARGC1A,CRCP,GPR75,GLUL,ZNF638,GPT2,KIF3A,BVES,ATOH8,AGBL5,IGF1,KLHL23,KIF5C,SMAD9,MATN3,MDM4,PPM1L,SLC11A2,PCSK1,PSD,APTX,MTMR10,TMEM145,QDPR,PLEKHB2,KLHDC8A,GSTCD,PTGR2,AMBRA1,SLC2A5,SEPHS1,SLIT1,WDTC1,CDK19,MCF2L2,RAP1GAP2,DDN,LHPP,SYNE2,FAM208A,TPCN2,USP22,SLC19A3,AKNA,PCDHA6,HIF3A,ARL10,TPM3,SSBP2,XPO1,WNK1,EVI5,URM1,SNX27,MPPE1" MicroRNA "ACACTGG,MIR-199B:MSigDB" "ACACTGG,MIR-199B:MSigDB" MSigDB 2.54E-28 1.43E-24 5.89E-28 5.43E-27 50 145 "RALGAPA1,ARID1A,PLEKHH1,ANK2,ALS2,PRX,DDX3Y,ATP2B2,FUBP1,MYRF,BTRC,DDR1,LARGE1,DNAJB5,CREM,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,EPB41L1,ERBB4,ZNF44,GCNT2,CSDC2,PPARGC1A,GRB10,KLF12,HLF,ARHGAP12,GIT1,RSPO2,PDE4D,PPM1B,RORB,ATXN7,NTNG1,ST6GAL1,WDTC1,KIF1B,LARP4,GANAB,SIRT1,ZFP91,ZNF17,RGMA,WNK3,ADAMTSL3" MicroRNA "ACACTGG,MIR-199A:MSigDB" "ACACTGG,MIR-199A:MSigDB" MSigDB 2.54E-28 1.43E-24 5.89E-28 5.43E-27 50 145 "RALGAPA1,ARID1A,PLEKHH1,ANK2,ALS2,PRX,DDX3Y,ATP2B2,FUBP1,MYRF,BTRC,DDR1,LARGE1,DNAJB5,CREM,MYEF2,KLHL3,SACS,ABCC5,TSPAN5,YAF2,PAN3,EPB41L1,ERBB4,ZNF44,GCNT2,CSDC2,PPARGC1A,GRB10,KLF12,HLF,ARHGAP12,GIT1,RSPO2,PDE4D,PPM1B,RORB,ATXN7,NTNG1,ST6GAL1,WDTC1,KIF1B,LARP4,GANAB,SIRT1,ZFP91,ZNF17,RGMA,WNK3,ADAMTSL3" MicroRNA hsa-miR-1207-5p:PITA hsa-miR-1207-5p:PITA_TOP PITA 2.76E-28 1.55E-24 6.39E-28 5.89E-27 54 171 "CNTNAP1,CACNA2D1,PLEKHB1,KMT2C,DLGAP3,AKAP5,ACBD5,ZNF385A,PNKD,G3BP2,CPEB2,ABCC5,CELSR3,APH1A,TMEM132E,PPP1R1B,HPCAL4,SYT3,CPLX2,ATF7,STMN2,IGF1,CAMK2N2,NRGN,PBX1,RETREG2,EPB41L4B,TNPO2,MED1,FAM120C,TMEM145,GTDC1,SETD5,FBXW7,SCN2B,YPEL4,SORCS3,TMCC1,NCDN,MAPK8IP3,VAMP1,SYP,ASTN2,CLASP1,PUM2,CBX5,TRPS1,TUB,ZIC3,GAL3ST3,NAV3,SLC17A7,VANGL2,ADAMTS10" MicroRNA "CCTGCTG,MIR-214:MSigDB" "CCTGCTG,MIR-214:MSigDB" MSigDB 2.87E-28 1.61E-24 6.67E-28 6.14E-27 61 220 "ACLY,SORCS1,ADORA2A,DGKZ,MARK4,JAZF1,CACNA1I,NRXN3,QKI,IGDCC3,CRY2,CSF1,SEC24C,RIMS4,RIMS3,MYEF2,SRGAP3,DNAJB6,PHC2,YAF2,EIF4G1,EZH1,AFF2,ARPP21,PCDH17,GRIN1,GRM7,SHISA6,KIFC3,PIK3AP1,MAPT,MID1,MOBP,MOG,NBL1,GPR85,RETREG2,SEPT4,OXR1,DUSP15,ARMC5,SALL1,MYO18A,ABLIM3,CPEB4,WDTC1,ZHX3,IQSEC2,RAP1GAP2,CAMTA1,CLASP1,DOCK9,TRPM2,TRPS1,FNDC5,KLC2,PCDH20,ZIC1,RGMA,PARP6,PIANP" MicroRNA hsa-miR-3666:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-28 1.63E-24 6.72E-28 6.19E-27 79 364 "ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,DAPK1,CEP170,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,SALL3,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PXK,PTPRG,RAB5B,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,SATB2,TCF7L2,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,ZNF711,ZNF24,ZNF154,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-6873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-28 1.82E-24 7.51E-28 6.92E-27 59 206 "RNF157,AK2,MTMR3,DDR1,CALM1,HAP1,FMNL3,CHRNB2,ARHGEF6,ENTPD4,PITPNM3,IST1,IP6K1,CHRDL1,TRAPPC9,MAMLD1,ST8SIA3,EIF4G1,EN2,HSPA12B,GFRA1,GLYR1,GNG3,TDRKH,SHISAL1,NKD1,SLC6A17,MAG,SAMD14,ZC3H12B,NPTX1,OGDH,ZNF827,CDK14,KCTD15,MTRF1L,TNPO2,PTPA,SLC22A23,NKAIN1,RAB5B,PRRT2,MYH14,MYO18A,RPH3A,CCDC88A,SLC11A1,SP2,ERC1,IQSEC2,ADAMTS17,TPM3,WBP2,TMPRSS5,VSNL1,ZIC2,ZNF70,PMEPA1,SIGLEC10" MicroRNA "TGCAAAC,MIR-452:MSigDB" "TGCAAAC,MIR-452:MSigDB" MSigDB 3.80E-28 2.14E-24 8.81E-28 8.11E-27 43 105 "SYN3,SORCS1,UNC5A,DOC2A,ANK1,LRCH2,ANK3,CHRD,ATP2B2,NRP2,CACNB2,SEPT7,DBT,DMD,ATL1,EPHB1,KCNMB2,SGIP1,AFF2,ATP2C1,GGT7,RNF165,STMN1,MBNL1,MMP16,NKX2-2,PCDH8,PCDH9,SEPT4,PPP2R5E,CNTLN,SALL1,SCN8A,CHD9,TRIM67,KIF1B,IQSEC2,NKAIN2,RPGRIP1L,DOCK9,TRPS1,ZIC1,MFF" MicroRNA hsa-miR-200c-3p:Functional MTI Functional MTI miRTarbase 4.08E-28 2.29E-24 9.44E-28 8.69E-27 60 214 "NLGN4X,TXNDC16,CDC14B,ARHGDIA,STX16,JAZF1,SEPT7,NOG,CFL2,QKI,BAG4,PHF14,RASSF2,ZEB2,MAMLD1,DNAJB6,EDNRA,ABI2,ELAVL2,ACSL4,TUBB3,DLC1,FLT1,CELF1,CAB39,SESN1,MALT1,RASSF8,TJAP1,LRP1B,NCAM1,NTRK2,PDPK1,PKD1,PRKCZ,MAPK7,UHRF1BP1,PTPN13,PTPRD,PTPRZ1,ZFHX4,WDR37,SLC1A2,ELMO2,RCOR3,MBD5,KIF13A,ZNF621,ERBIN,CAMSAP2,TCF7L2,ZEB1,USP22,PSD3,SIRT1,ZFPM2,ZMAT3,TRPS1,TUBB2A,WIPF1" MicroRNA hsa-miR-1237:PITA hsa-miR-1237:PITA_TOP PITA 4.08E-28 2.29E-24 9.44E-28 8.69E-27 60 214 "ESYT2,BCAR3,AMPH,APBB1,ASTN1,SLC4A4,EIF4G3,GPC2,SLC25A14,NRXN3,NIPBL,SLC4A7,AHCTF1,ZNF385A,CREB5,TENM4,FRMPD4,KIAA0513,SPATA2,ZEB2,SMG7,G3BP2,MED12L,UBE2E3,STAG2,GFRA1,TCERG1,SPIN1,PCLO,GRB10,GRIK2,PTPRT,HLF,KCNA1,KIFC3,ARHGAP12,MAT2A,PTPRD,FAM120C,FIGN,RFX2,ZFHX4,RAVER2,RYR3,CPEB4,ZCCHC24,ZNF423,NKAIN2,LRRC4,PHLDB1,ANKRD28,GZF1,TNS1,ZIC2,WNK3,PAK5,KAT6A,HNRNPA3,FXR1,JPH3" MicroRNA "GTGCAAA,MIR-507:MSigDB" "GTGCAAA,MIR-507:MSigDB" MSigDB 4.13E-28 2.32E-24 9.57E-28 8.81E-27 47 128 "SORCS1,SLC24A4,PCDH19,UNC79,NCOA1,ATP2B2,SLC4A7,LONRF1,DLG3,DYRK1A,KMT5B,EIF4G2,RGS17,STAG2,GRIK2,BACH2,AGFG1,KCND2,KCNJ3,MARK3,MBNL1,MEIS1,NELL2,NEUROD1,NKX2-2,PAX6,PCDH9,MDGA2,USP47,REV3L,PBRM1,FBXW7,SEMA6D,SCN3A,CHD9,DHX30,TET1,CPEB4,HECW1,IQSEC2,ANKRD12,ADGRL3,ANO4,THRA,MEAF6,ZIC1,FMN2" MicroRNA hsa-miR-4295:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.27E-28 2.40E-24 9.87E-28 9.09E-27 79 366 "ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,DAPK1,CEP170,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,SALL3,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PXK,PTPRG,RAB5B,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,SATB2,TCF7L2,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,ZNF711,ZNF24,ZNF154,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-532-3p:TargetScan hsa-miR-532-3p TargetScan 4.46E-28 2.50E-24 1.03E-27 9.50E-27 64 244 "ADCYAP1R1,MTA3,PDZD4,BCAS1,APP,EIF4G3,ATP2B1,CADM3,BSN,MAP7,P2RX6,DGKI,CDH2,NRXN2,HECTD1,NIPBL,LETMD1,SEC31B,CSF1,IPCEF1,KIAA0087,CTIF,DRP2,CELSR3,ABI2,ELAVL3,ETV1,HPCAL4,NPTN,GABRA4,ATP8A2,GFRA1,PPARGC1A,CBX1,PTPRT,IL1RAPL1,NXPH3,NEGR1,LRRTM3,KCND3,MBD1,MDM4,PPM1L,MMP16,NFIX,NPTX1,CAMKV,PIGG,BSDC1,DPF2,CYB561D1,PRCD,MYO18A,AMBRA1,LRRC55,SCN3B,NMNAT2,PEG10,NFASC,GPRIN3,C5orf64,GDPD5,MSRB3,PIANP" MicroRNA hsa-miR-876-5p:TargetScan hsa-miR-876-5p TargetScan 4.47E-28 2.51E-24 1.03E-27 9.51E-27 62 229 "ADARB2,AXIN2,HACE1,OGT,ANK1,PARG,ARNTL,DST,FUBP1,MTMR3,CDC27,CHM,QKI,NIPBL,COL9A2,LIN54,DBN1,PLEKHM1,MAGI2,MTX3,DYRK1A,ABI2,RGS17,EN2,DNAJC27,ANKFY1,NPTN,CAMKK2,GABRB1,FAXC,GLYR1,CELF3,NEGR1,C2orf72,IL6R,KCNN3,MAP4,MBNL1,PPM1L,MN1,NAP1L1,PAK3,PAX6,PDE3B,GPR173,POU6F1,MED1,CNNM2,PTPRD,CEP97,KLHDC8A,RORB,RIMKLA,RXRA,ATXN1,HKDC1,ATF7IP,PDZD2,ERC1,CUX2,NSD1,GPRIN3" MicroRNA hsa-miR-433-3p:TargetScan hsa-miR-433-3p TargetScan 5.13E-28 2.88E-24 1.19E-27 1.09E-26 63 237 "INTS2,HECW2,MIER1,ATP6V0A1,AIFM1,CDC27,FOXN3,CLCN3,NMT2,CLTC,QKI,NSL1,CCDC144A,PYGO1,HP1BP3,MTX3,ABCC9,FSD1L,RBM12,GPR61,ENPP6,ERBB4,EXTL2,KATNAL1,CELF1,CHL1,ILDR2,HBS1L,NCKAP1,ALDH1L1,PPARGC1A,FERMT2,NEGR1,HTR5A,IGFBP1,CLVS2,KPNA5,LRRC4B,MN1,MXI1,HCN1,GPR137C,MED1,PRKCB,MAPK8,CEP97,PBRM1,RPRD1A,CCDC82,FBXW7,CLIP1,CHD9,NUBPL,EPN2,CMTR2,ANKRD12,FAM208A,NSD1,ANO5,PLEKHH2,RBFOX3,GDPD5,GAN" MicroRNA "ATGTTTC,MIR-494:MSigDB" "ATGTTTC,MIR-494:MSigDB" MSigDB 5.29E-28 2.97E-24 1.22E-27 1.13E-26 50 147 "DSCAML1,OSBPL6,OGT,API5,SHTN1,ARHGAP5,ARNTL,CAMK2D,CANX,CLTA,DBN1,DMD,EGR3,EIF5,NBEA,TACC2,NSG2,GABRA5,PPARGC1A,GRIK2,ADAMTS6,HAS2,ELOVL5,LMO1,LRP1B,ZC3H12B,NEUROD1,NOVA1,PCSK1,PRTG,ING3,POU3F2,ANKHD1,TMEM255A,CHD9,FBXO11,SMARCE1,MBD5,SON,SP4,STAC2,SYNE2,TAC1,TACC1,SZT2,ARHGEF12,TRPS1,ZIC2,CERS6,ADAMTSL3" MicroRNA hsa-miR-6511a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.34E-28 3.00E-24 1.23E-27 1.14E-26 94 504 "SDE2,ABCF1,XKR4,PLEKHG5,ELFN2,PNMA8B,HECW2,TRMT9B,SHROOM2,ARHGDIA,DNAH17,ATM,BSN,DDR1,CANX,ISPD,CBFA2T2,DLGAP3,NRXN3,AKAP5,UBXN2A,PHF19,TMEM170A,DNAL1,EBI3,RASA4,MRNIP,MTSS1L,IGSF6,ANKMY1,KATNAL1,ZNF589,VTI1B,TRMO,TMEM151A,GABRB1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,FERMT2,KIF3A,KAT7,DDX19B,SCRG1,ZNF546,RBPJ,IBA57,COMMD5,CCDC80,NBL1,CNOT4,NUCB1,PDGFRA,CCSER2,PLXNB1,RETREG2,POLR2F,QDPR,RAB5B,PLEKHB2,ZNF793,ATXN1,SCN2B,SLC30A10,IL17RB,CPEB3,MYO18A,MAGI3,ATF7IP,SCN3B,KIF1B,ZSCAN29,NEK4,ACSBG1,SLC37A2,CAMSAP2,FAM208A,SATB2,NACC2,RBFOX2,TPM3,PPIL6,UBTF,ZNF708,ZNF70,AMZ1,DPYSL5,EVI5,SNX27" MicroRNA hsa-miR-504:mirSVR_highEffct hsa-miR-504:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.46E-28 3.07E-24 1.26E-27 1.16E-26 80 376 "CLK4,NBAT1,KLHL32,ZNF608,TAOK1,ALCAM,PCDH10,CDK10,CFLAR,IL33,LURAP1,KALRN,SLC5A11,CDC27,CBARP,DNAJB5,SUMF2,ANKRD44,FEZ1,UBXN2A,RUSC2,CEP170,NTM,DPYSL2,MBNL2,COPS4,TMEM74,DLC1,CAP2,SEMA4D,CELF1,DKK3,CHL1,ZMYND11,GART,PCDH17,LYVE1,STARD3,ZNF638,GPR12,GRM3,SMAP1,SOWAHA,KCNK2,KLC1,INSYN2,FGFBP3,BLOC1S2,MYO7A,MYO9A,CNOT4,ODF2,ZDHHC22,SLC10A4,ANLN,TMEM38A,NLE1,PLCB2,PLCL1,FTO,MINDY2,RAB39A,PKN2,CYBC1,GON4L,SH3TC2,MCMBP,COPZ1,ASAP3,BTBD7,MYT1L,NXT2,ASTN2,ZMAT3,TSC1,OSBP2,FSTL5,HPS4,GAL3ST3,ADAMTSL3" MicroRNA hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 5.96E-28 3.35E-24 1.38E-27 1.27E-26 83 403 "RNF150,NLGN4X,NME5,ALCAM,TRMT9B,APBA2,APBB1,APBB2,CPNE5,STX16,MYOM1,CCKBR,CLCN3,SUMF2,SLC32A1,CSF1,CYBB,MTX3,DLG2,CALN1,SLC25A18,FRY,EPB41,ENPP6,SYNCRIP,IQCG,SARAF,NEURL4,TUBA8,GDF9,GFRA1,TNRC6A,EML4,ADAMTS6,HMGB1,IGFBPL1,ZDHHC15,HSP90AA1,ZIC5,IGSF1,CDH20,KCNJ16,KCNQ2,MATN3,SESN3,CNOT4,NPTX1,PROX1,MTMR10,KHDRBS2,RFX3,GSTCD,CCDC92,FAM81A,BTBD3,YPEL4,BTBD7,MAST1,USP33,SOX11,CLUAP1,CDK19,ATP10B,LARP4,INKA2,SYNE2,TACC1,FBXW11,TCF7L2,SYNE1,DICER1,AP4E1,HEY2,PDSS1,UGT8,OSBP2,TOM1L2,PLPP4,CA10,RGMA,RTN4,FXR1,CPNE4" MicroRNA hsa-miR-27b-3p:Functional MTI Functional MTI miRTarbase 5.98E-28 3.36E-24 1.38E-27 1.27E-26 85 421 "DPF1,SLC25A25,ADAR,ADD1,FZD9,KIAA1211,OSBPL6,TAOK1,SEMA6A,GPAM,ARNTL,MTMR3,HIP1R,SPAG9,CCNT1,SOCS6,KMT2C,CNN3,PNKD,RGS6,CTNND1,LONRF1,LIN54,ELMO1,C2CD2L,ZC3H11A,SEC16A,NR1D2,ATN1,EDNRA,PHC2,FEM1B,TMTC1,EGFR,EIF5,EML1,EN2,TOMM40L,GTF2IRD2,SUCO,CELF1,OGA,CAB39,ZMYND11,SRCAP,NUDT21,RAPGEF1,MIER3,SLC6A17,LIFR,PAXBP1,NF1,NFE2L2,OLR1,RETREG2,MAPK9,BDNF-AS,RET,ALG9,SEMA6D,COPZ1,FNDC3A,CPEB4,ZFP1,WDTC1,ERC1,PEG10,KIF1B,TROVE2,POGZ,MPRIP,GSE1,NSD1,FRYL,TGFBR3,ZNF106,ZNF384,RGMB,TTC3,ZNF45,WNK1,MFF,CAB39L,AP3B2,SPATA13" MicroRNA hsa-miR-3163:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.00E-28 3.37E-24 1.38E-27 1.27E-26 76 342 "SDE2,XKR4,ADD2,ZNF608,WDR35,TXNDC16,SPOP,USP28,NUMB,ZNF582,NRP2,CALM1,RUNX1T1,BTF3L4,NECTIN3,OSBPL3,ATRNL1,USP6NL,CENPL,MTX3,CDON,CPEB2,ELAVL4,MRVI1,CACNG2,ACSL4,SCML2,DLC1,PNMA2,MSANTD4,GABRB3,NCKAP1,GCK,TCERG1,COPS8,RNPS1,TNRC6A,PRRC2B,USP51,ZIC5,SCIN,STMN1,CHIC1,ZNF680,MYBPC1,IGSF11,PFKP,ST8SIA5,PPP2R5E,MAPK8,PTPRD,REV3L,GTDC1,KLHL11,TMLHE,ACER3,CLIP1,CHD9,BTBD3,SLC6A8,SON,TROVE2,AJAP1,ZC3H4,PRRC2C,ARC,TBCEL,TBL1X,TPCN2,RBFOX2,TPM3,RGMB,TUBB2A,MEAF6,WIPF2,GAN" MicroRNA hsa-miR-608:PITA hsa-miR-608:PITA_TOP PITA 6.11E-28 3.43E-24 1.41E-27 1.30E-26 48 135 "ASIC1,PITPNM2,CNIH2,SEMA4G,CADM3,SYNJ1,CABP7,ZMYM4,DLGAP3,CABP1,ZNF385A,SH2B1,CLIP3,RAB39B,DMPK,EBF1,EIF4G1,ELAVL3,ANKRD13B,SLC43A2,NRN1,PPP1R1B,AGAP3,SRCAP,SMAP1,LRRTM1,CAMK2N2,GIT1,MDGA1,NEXMIF,NFIX,PDE1B,PSD,TMEM255A,GTDC1,NCBP3,SCN2B,YPEL4,SNAP25,PALLD,NPAS3,GANAB,VAMP1,SYP,RPGRIP1L,CBX5,PARP6,RTN4" MicroRNA hsa-miR-486-5p:PITA hsa-miR-486-5p:PITA_TOP PITA 6.19E-28 3.48E-24 1.43E-27 1.31E-26 47 129 "KCNH8,ARID1A,SLC12A5,SORCS1,MRTFA,ARHGAP5,DYNLL1,LYPD1,G3BP2,GRIN3A,DYNC1I1,RBM12,ELAVL2,FGF13,CSPG5,GABRB3,CIT,MIER3,MYLK2,IGF1,KCNA1,CYP27C1,MARK1,HCN1,PIK3R1,TRHDE,FAT3,PPP3CB,RGS4,ST6GALNAC6,ATXN1,NLGN1,RCOR3,PDZRN3,SMOC1,LRRC4,ST5,PRRC2C,TCF4,PUM2,KAT6B,NR2C2,CADM1,FLRT2,NSD2,SMARCAD1,HNRNPA3" MicroRNA hsa-miR-4649-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-28 3.51E-24 1.44E-27 1.32E-26 94 505 "SDE2,ABCF1,AS3MT,ARID1A,XKR4,NDRG3,SLC24A4,TXNDC16,APAF1,AQP6,CDC14B,SFMBT2,ASPA,ATM,ZNF583,ZNF555,PTBP2,SLC16A4,GPR37L1,NRXN3,AKAP5,MFSD4A,SLC35F1,CRY2,IPCEF1,GREB1,SEC14L5,KIAA0408,KIAA0513,LONRF1,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,GNE,E2F6,SYT15,HEYL,RASA4,IRAK4,MRNIP,VPS26C,ZNF585B,TOMM40L,ZNF589,ATP13A4,MSANTD4,GPR75,GLUL,ZNF638,KIF3A,BVES,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,BLOC1S2,SLC11A2,NUCB1,NUCB2,MTMR10,TMEM145,ZNF844,QDPR,PLEKHB2,GSTCD,SNX22,PTGR2,SALL1,IL17RB,SH3BP2,SLC2A5,SEPHS1,PEG10,KIF1B,CDK19,DDN,LHPP,ZSCAN29,FAM208A,AKNA,PCDHA6,AHCYL2,ARL10,TPM3,SSBP2,TUBB2A,USP1,EVI5,SNX27,MPPE1" MicroRNA hsa-miR-221-3p:Functional MTI Functional MTI miRTarbase 6.26E-28 3.52E-24 1.44E-27 1.33E-26 79 368 "ARID1A,TMEM132B,ADD1,BRAP,AP2A1,USP28,PHF12,APAF1,DDX3Y,EIF4G3,ATP2A2,CDC27,HECTD1,CNRIP1,RBM39,TOMM20,ZEB2,ELAVL2,MTSS1L,ERBB4,FOXO3,EVL,SMC2,STAMBP,RNPS1,GLYR1,TUBA1C,GRB10,FICD,ADAMTS6,KIT,STMN1,LIMS1,HECTD2,MAT2A,MBNL1,NFYA,PIK3R1,PKM,POLG,POU3F2,MAPK10,SLC25A36,RPL15,ATXN1,ZFP30,KIF16B,SLC6A9,SEPHS1,ZFP1,TMCC1,SOX11,ERC1,PEG10,POGZ,ANKRD28,IQCE,SLC19A3,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,SIRT1,TIAM1,ASXL3,RUNDC3B,TRPC3,TRPS1,TSN,TUB,UBC,AMOT,SF1,CIAPIN1,NHSL1" MicroRNA hsa-miR-27a*:mirSVR_highEffct hsa-miR-27a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.00E-28 3.93E-24 1.61E-27 1.48E-26 86 431 "DPY19L2P4,ZNF608,HECW2,HFM1,FAM135A,ANXA7,BCAS1,SEMA4G,ATM,RNF182,DCAF5,DST,CANX,LARGE1,CNR1,CNTFR,ENTPD4,CLIP3,CSF3R,CX3CR1,ZEB2,HP1BP3,COPS7A,CEP170,PDCD6IP,DNM1L,EIF5,TENM1,TMEM35A,SRRM1,TMEM74,PRMT5,FOXG1,NELFCD,C2orf88,USP21,DLL3,HEPN1,MSL3,KDM2B,ADGRA3,GRM7,BTN2A1,LINC00839,HLF,INPP5B,ITPKB,KCNJ16,STXBP5,L1CAM,LAMP2,NFIA,SLC11A2,CLDN11,MED1,HYDIN,MASP1,BCAS3,VPS13C,PTK2,ENOX1,RPRD1A,CARF,SNX22,ATXN2,ITSN1,SMTN,SLC8A3,SLC11A1,SLIT1,SOX1,KIF21B,ZC3H13,TAB2,SEPT3,SYT11,KLHL4,PCDHB4,ASXL3,PCDH20,EMSY,DNALI1,SNX27,RGS7BP,IFT88,CPNE4" MicroRNA hsa-miR-6838-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-28 3.93E-24 1.61E-27 1.48E-26 86 431 "AXIN2,FZD9,ADORA3,CASKIN1,TAOK1,TRMT9B,OGT,ARMC12,APP,CASK,ARHGDIA,ZBTB10,DOCK11,MTMR3,FOXK1,CA8,CANX,RUNX1T1,CCNT1,DLGAP3,CLU,TBPL1,BAG4,ZFP28,CSNK1E,OSBPL3,SOCS5,RUBCN,ARHGAP32,PHF19,RASSF2,RIMS3,PHYHIP,YTHDC1,DMPK,DMTF1,FCF1,HEYL,SIDT2,PLEKHA1,EN2,ZNF391,ANKMY1,ZNF585B,CAMSAP1,MSANTD4,NCKAP1,RNPS1,GNAL,NEGR1,MSL1,RBPJ,LAMP2,ARHGAP12,CHIC1,CCDC80,MYO5A,OCRL,PDE4D,PIK3R1,PSAT1,PPP2R5C,PTPRD,PLEKHB2,RBBP6,ZFHX4,TMEM100,SALL1,HSPA4L,CPEB3,ANKRD36,KANK1,SYPL1,ZMAT3,TGFBR3,TPM2,TPM3,TUBB2A,UBE2H,AMOT,VAV2,ZBTB16,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-770-5p:PITA hsa-miR-770-5p:PITA_TOP PITA 8.98E-28 5.04E-24 2.06E-27 1.90E-26 48 136 "CCDC85A,OGT,ANK3,ARHGAP5,EIF4G3,CABP7,NMT2,CNR1,BTF3L4,SLITRK5,IST1,SACS,G3BP2,TMCC2,CPEB2,SLC12A6,MBNL2,RCAN2,EPHB1,RRAGB,GRIA2,KCNJ11,KCNK1,STMN1,ARHGAP12,MARK1,MYO6,NCAM2,NTRK2,STRN3,NXPH1,UHRF1BP1,FAM120C,PTX3,RAP1GDS1,GTDC1,FIGN,CPEB3,MAGI3,SOX2,SP4,NMNAT2,ELOVL4,SZT2,TMEM178A,SCG2,SLC17A6,GOPC" MicroRNA hsa-miR-595:PITA hsa-miR-595:PITA_TOP PITA 9.31E-28 5.23E-24 2.14E-27 1.97E-26 60 217 "CSMD3,PCDH19,OSBPL8,CEP126,BCAR3,MAP4K3,ZBTB10,ATP2B1,CALM1,REPS2,LGI1,NRXN3,HECTD1,PUM1,HDAC4,MYEF2,CPEB2,DYRK1A,RBM12,WAC,ACSL4,ZIC4,TAOK3,MED12L,FOXF2,SYNCRIP,FUT9,BRPF3,NCKAP1,GRIA2,IGF1,PLD5,MAT2A,CHIC1,AFDN,NCAM1,NFIA,GPR88,GPR85,CDK14,PRRX1,FAM120C,RAP1GAP,GTDC1,RGS7,ATXN1,CPEB3,CPEB4,SORCS3,MBD5,PDZD2,SATB2,TPM1,PITPNB,FLRT2,MKRN3,TMEM237,EMSY,PDSS2,RNF146" MicroRNA hsa-miR-324-3p:PITA hsa-miR-324-3p:PITA_TOP PITA 1.00E-27 5.63E-24 2.30E-27 2.12E-26 54 175 "CSMD2,SORCS1,ADRA1B,LRFN1,CNIH2,BSN,FMNL3,FOXN3,KMT2C,SLC25A27,ZNF385A,SH2B1,SEC24C,RIMS4,FAM131B,YTHDC1,C2CD2L,G3BP2,PHC2,EFNA3,ELAVL3,RASGRP2,ANKRD13B,AGAP2,SEMA6C,STAG2,SRRM4,RND1,TNRC6A,SOWAHA,KIF5C,MDGA1,PBX1,OLA1,PIK3R1,RAB5B,ZNF532,KIRREL1,ATXN1,SHC4,FAM214B,SORCS3,WDTC1,ERC1,GANAB,AJAP1,GSE1,ATP11A,CAMTA1,THRA,CADM1,SPHK2,PARP6,WNK2" MicroRNA hsa-miR-198:PITA hsa-miR-198:PITA_TOP PITA 1.09E-27 6.11E-24 2.50E-27 2.30E-26 50 149 "ATP1A3,ADGRB3,JAZF1,BSN,CAMK2G,FOXN3,NRXN1,CREB5,SEC24C,SLITRK5,ERC2,DNAJC6,SRGAP3,DLG3,DLG4,DPP6,FAM135B,APH1A,MBNL2,AGAP3,ARFGAP2,JPH4,KDM2B,RAPGEF4,KLF12,KCND1,CHIC1,MEIS1,CNOT4,DDR2,PBX1,RETREG1,LRRN3,PRKAB2,PSD,DBX2,FIGN,RIMKLA,ATXN7,ZNF821,SH3GL3,PKNOX2,SLC8A1,SCMH1,CDK19,POGZ,FBXW11,TCEA1,PUM2,SOCS4" MicroRNA hsa-miR-208b:mirSVR_highEffct hsa-miR-208b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.09E-27 6.13E-24 2.50E-27 2.31E-26 56 189 "FAM131A,TMEM108,BLM,SYNJ1,PRC1,CDO1,CHN2,QKI,MAP4K4,IQCK,HS3ST5,ZNF804A,CPEB2,EDNRB,KCTD3,MED12L,FOXG1,ANKFY1,GABRA2,SALL3,DISC1,CBX1,GNAS,GRIA2,GRIA4,RNF165,WIF1,HNMT,CELF5,MAOB,GPR88,TRHDE,PPP2R5C,PEX2,USP47,RGS7,RIC8B,PNMA8A,ROBO2,FBXW7,TCP11L1,RYR3,SCG5,CHD9,RCOR3,TTC17,ARHGEF9,SATB2,ZEB1,DOCK9,RALYL,ERCC6L2,CADM1,MICU3,PCDH15,PHTF2" MicroRNA hsa-miR-6849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-27 6.31E-24 2.58E-27 2.37E-26 116 731 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,DOCK11,AP1M1,ISPD,CBS,CCNT1,SLC16A4,NRXN3,SUSD5,PPP1R16B,UBXN2A,CTH,GREB1,USP6NL,RASSF2,TMEM170A,DNAL1,YTHDC1,MTX3,CALN1,TOM1,EBI3,MRO,ABI2,APC2,ANKMY1,ZNF589,ANKFY1,TRMO,CELF1,GABRA4,ZNF44,B4GALNT1,ZNF234,FAXC,SRCAP,CRCP,GPR75,GLUL,LUZP2,LILRA2,RAPGEF1,NR3C1,DDX19B,AGBL5,ATCAY,DOCK7,KIF5A,LAMP2,MAG,CHST6,MMP17,CCDC80,LAYN,ZC3H12B,SFR1,SLC11A2,SNTG1,CCSER2,MTRF1L,STK32A,PTPRB,TMEM145,PEX2,ZNF844,RAB5B,CEP97,KLHL11,KLHDC8A,SNX22,NCBP3,ZNF331,FOXRED2,CSRNP3,HOGA1,IL17RB,HSPA4L,MAGI3,URGCP,PREX2,SEPHS1,RADIL,ANKRD36,FAM126B,EMC1,MCF2L2,SRPK2,SSTR2,INKA2,NEK4,SYT11,C3orf70,SLC37A2,AHCYL2,PPIL6,SSBP2,TMEFF2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,ZBTB16,WNK1,TRIM16L,PIANP,AP3B2,GAN" MicroRNA hsa-miR-548d-3p:Functional MTI Functional MTI miRTarbase 1.37E-27 7.69E-24 3.14E-27 2.89E-26 70 296 "ARID1A,TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,CDK5R1,MTMR3,FMNL3,CDC27,NRXN1,ATRNL1,FAM169A,PHF19,TOMM20,PITPNC1,EDIL3,HIPK3,YAF2,CELSR3,MRO,ERBB2,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,MDM4,THYN1,MYBPC1,MYO6,KCNK10,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,NWD1,ARID4A,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,LRRC55,ATF7IP,SNCB,FAM126B,KIF1B,FAM208A,ALG1,CLASP1,HHIP,ARL10,TJP1,TP53BP2,TRPC3,SF1,MKRN3,GAL3ST3,NAV2" MicroRNA hsa-miR-299-5p:PITA hsa-miR-299-5p:PITA_TOP PITA 1.75E-27 9.80E-24 4.00E-27 3.68E-26 53 170 "ABR,CSMD3,KLHL13,ALCAM,ARHGAP5,STX16,CDK5R1,BTRC,FOXN3,SULT4A1,SLC4A7,CS,SOCS5,HDAC4,LONRF1,G3BP2,CPEB2,HIPK3,ELN,WAC,FOXG1,TBR1,PHYHIPL,MEGF10,CAB39,IQGAP2,AHDC1,GFRA2,KLF12,DHX35,ZIC5,USP54,MAT2A,KITLG,HCN1,PCDH8,PFKFB2,NLGN3,RFX5,ROBO1,SCN2A,SGK1,CHD9,CCDC88A,SOX11,CLSTN2,POGZ,PLCB1,CAMSAP2,PUM2,NR2C2,NAV3,KCNAB1" MicroRNA hsa-miR-149:PITA hsa-miR-149:PITA_TOP PITA 1.75E-27 9.80E-24 4.00E-27 3.68E-26 53 170 "PCDH19,SPOP,CACHD1,SEMA4G,SLC4A4,ADGRB2,BCL2L2,SOCS6,B4GALT6,CREB5,NCOR1,SNCAIP,SEC24C,RIMS4,CNTNAP2,LONRF1,KLHL3,DLG3,DLG4,EDNRA,CNNM1,EIF5,TENM1,OLFM1,FOXO3,AFF2,BRPF3,KAT7,FAM222A,ARHGAP19,KCNK2,CHIC1,MITF,GIT1,MSI1,NFIX,NNAT,SLC11A2,MED1,RNF220,TNFRSF19,BTBD3,SNCB,KIF1B,NCDN,PHLDB1,TCF12,FBXL16,VLDLR,SF1,POLR3H,PDSS2,MSRB3" MicroRNA hsa-miR-193b:PITA hsa-miR-193b:PITA_TOP PITA 1.75E-27 9.85E-24 4.02E-27 3.70E-26 49 144 "KCNH8,UPRT,STX16,BCL2L2,CALB1,CALM1,RUNX1T1,KIAA1549L,CTNND2,FAM131B,ZC3H11A,DYRK1A,RBM12,EN2,ETV1,FGF1,ANKFY1,ST6GALNAC3,BRPF3,GNAO1,CAMK2N2,STMN1,MYCN,NEXMIF,NOVA1,PCSK2,CAMKV,CCSER2,PPP2R5C,MSANTD2,ATXN1,CLSTN1,YPEL4,SLC20A2,ZHX3,HECW1,ERBIN,ST5,CAMTA1,AGTPBP1,TCF4,DMXL2,ARHGEF12,LRRC8A,R3HDM1,CADM1,ZIC3,NAV3,RNF146" MicroRNA hsa-miR-1249:mirSVR_lowEffct hsa-miR-1249:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.90E-27 1.07E-23 4.36E-27 4.01E-26 72 314 "DGCR6,SLC12A5,ADGRF5,ANK3,CDK13,MARCH3,KALRN,CBLN1,P2RX6,L3MBTL4,MAGI1,RAB28,MAP4K4,COX4I1,SMARCAL1,SLC32A1,RGS6,ARHGEF10,DOCK4,HDAC9,TIAM2,SACS,DNM1L,E2F5,PHC2,FRY,EFNB3,PHF20L1,CEND1,FCGR1A,GORAB,MEX3B,AGAP2,NOP56,AKAP3,KHDRBS3,NSG2,SEPT9,DCLK2,GRIA4,SPACA9,GRIK4,GRIN1,FRMD3,HNRNPK,IL12A,KCNJ3,KHK,LINC00634,FGFBP3,MSI1,PABPC1L2A,SFR1,CNOT4,PKIA,PIGG,RGS3,CSRNP3,LINC00461,NUBPL,CXXC4,IFT122,SOX2,CLSTN2,CAMSAP2,TMEM136,TCF7L2,THRA,TNR,FAM155A,OSBP2,FMN2" MicroRNA hsa-miR-567:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-27 1.11E-23 4.53E-27 4.17E-26 56 191 "TMEM132B,HACE1,SORCS2,TAOK1,APP,CFL2,IGLON5,MYADM,DCAF8,SV2B,DMD,MBNL2,ABI2,CERCAM,EPHA5,KATNAL1,UBE2E3,JKAMP,GABRG1,GATM,SESN1,MMADHC,CBX1,BVES,ZDHHC15,IGF1,DOCK7,KCNJ3,KCNQ3,SYT9,MKLN1,MYO5A,NELL2,NEUROD2,OPCML,PLP1,SDK2,SPATA6,PROX1,OXR1,RIC8B,PGBD4,SATB1,CSRNP3,PEX26,SMTN,PEG10,KIF1B,NECAB1,ARHGEF9,PLCB1,HHIP,CSMD1,KCNK12,ADAMTS9,SSPN" MicroRNA hsa-miR-4281:mirSVR_lowEffct hsa-miR-4281:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.07E-27 1.16E-23 4.74E-27 4.36E-26 83 410 "GALNT16,PNMA8B,SLC24A4,LRRC7,LRFN1,SEC11C,RGS9,BCL2L2,MIR9-3HG,PTBP2,RHBDL1,CBR1,P2RX6,CDH18,EPS15L1,SOCS5,IST1,SGSM2,DNM1,TOM1,DNAJB6,SEZ6L2,TSPAN5,APH1A,SEZ6,ERBB2,SPEG,DNAJC27,FER,ATP13A4,ZNF276,STARD3,GNG3,GPM6A,CECR2,GRIA1,GRM5,HPSE2,AGBL5,LIX1,MAN2A2,MARK1,MAT2A,MBD1,MBNL1,TM6SF1,MEIS1,STK32C,SMIM11A,SETD4,TMIE,MAPK3,MAPK4,MAPK9,RALGDS,YJEFN3,NCBP3,SMPD3,PPP4R3A,SMTN,SLC11A1,CPEB4,ZNF667,SNCA,CMTR2,MYO16,CAND2,SPTB,TSPYL2,SSTR1,TRIM2,TNS2,KHDC1,TK2,CDK20,PPIL6,PLPPR2,VAV2,CELF4,MEIS3,SLC30A3,STMN4,CBLN2" MicroRNA hsa-miR-3144-5p:mirSVR_highEffct hsa-miR-3144-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.35E-27 1.32E-23 5.37E-27 4.94E-26 72 315 "SYS1,LRCH2,PHF12,SUGT1P4-STRA6LP-CCDC180,PKP4,BCAS1,CAPRIN2,CAMK2G,ARHGEF25,CBR1,CBS,CERS5,MAGI1,SH2B1,SEC24C,DCAF8,FRMPD4,DCTN1,C2CD2L,EPHB1,ZNF589,FGF11,STAU2,GABBR1,GABRB1,DISC1,SESN1,HEPN1,AIFM3,CNDP1,B4GALNT4,GUCY1A2,MAEL,FAM95B1,INSM1,MOBP,BLOC1S2,NRBP2,MTR,MYCN,LAYN,NPR2,NRGN,PDPK1,GNG2,MAPKAP1,SEPT4,DEF8,RGS12,FAM182A,AMER2,SCN3A,ITSN1,SH3GL3,CNKSR2,SLC1A7,SLC6A8,ARHGEF40,PEG10,CDK19,LMO3,STOX1,STAU1,TTBK2,UNC5D,CLASP1,TPM1,AMACR,FNDC5,TTC3,AMOT,VAV1" MicroRNA hsa-miR-1304-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.61E-27 1.47E-23 5.96E-27 5.49E-26 95 524 "CLK4,TMEM132B,TEX22,MTA3,PHF12,CDC14B,KIAA1614,BMP7,FOXK1,DIRAS1,MAP7,ZBED1,CDH8,DIS3L,RTTN,RNF14,HINFP,UBXN2A,SEC14L5,FGFR1OP2,DBN1,DBT,ZBTB24,KRBA2,HEYL,IRAK4,MRNIP,RGS17,TUBD1,PLEKHO1,COQ7,SLC43A2,IGSF6,SRARP,TESK2,FGFR1,SEC23B,APOPT1,MSANTD4,NCKAP1,MYOZ2,DBF4,KDM2B,RAB40B,CNDP1,LILRA2,RFFL,ATOH8,DDX19B,HMGB1,SCRG1,ZNF546,NKD1,IL6R,IBA57,CYP27C1,LIMS1,GPR155,MOG,SAMD5,ZDHHC22,ZDHHC8,ZNF655,A2ML1,ZNF426,STRN3,EXOSC10,FITM2,APTX,PIGG,MTMR10,ELP2,UEVLD,DRAXIN,PEX26,ZNF430,ATF7IP,BDP1,INKA2,KLHL7,SLC37A2,ALG1,WWC1,ACSL6,TPCN2,PCDHA6,ZNF106,FBXL16,ARL10,FAM124A,ZNF384,FNDC5,ZNF708,LMAN2L,LINC00632" MicroRNA "CTTGTAT,MIR-381:MSigDB" "CTTGTAT,MIR-381:MSigDB" MSigDB 2.66E-27 1.49E-23 6.07E-27 5.59E-26 56 192 "EIF4G3,CARMIL3,KALRN,NRXN1,QKI,OSBPL3,MBNL2,KCTD3,EIF4G2,PAN3,EIF1,EPB41,EPB41L1,SRRM1,RRAGB,DLC1,FOXF2,SYNCRIP,NBEA,GAD1,ZMYND11,ARPP21,C15orf41,GFRA1,GRM1,GRM8,PSIP1,KLF12,MAP4,MEIS2,MITF,NFIA,KCTD15,PURG,PMP22,KANSL1,SNRK,ZNF532,SEMA6D,SATB1,SCAF8,SLC6A8,SHANK2,BTBD7,KIF1B,IQSEC2,LRRC4,ANKRD12,ANO4,ZFPM2,R3HDM1,UBE3A,TBC1D15,VSNL1,NAV3,ST8SIA2" MicroRNA hsa-miR-548aw:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-27 1.55E-23 6.30E-27 5.81E-26 66 267 "ADARB2,SPOP,GAS7,STX16,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,KIAA0513,DBN1,G3BP2,TMTC1,RCAN2,EPHB1,TAOK3,MED12L,CAMSAP1,ZMYND11,MALT1,RAB30,PRRC2B,DIPK1C,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,PPP2R5E,PRKACB,MAPK8,NWD1,RAVER2,FOXRED2,SGK1,PEX26,SLC6A8,ATF7IP,KIF13A,SPART,POGZ,DIP2A,ARC,UNC5D,DICER1,TUBB2A,ZBTB38,ZNF154,SLC30A4,ZXDA,MFF,STOX2,ITM2C,WNK3,HNRNPA3,FXR1" MicroRNA hsa-miR-519c-3p:Functional MTI Functional MTI miRTarbase 2.91E-27 1.64E-23 6.64E-27 6.12E-26 76 350 "ADAR,ADARB2,TAOK1,SEMA7A,CAPRIN2,NIPA1,MAP7,CFL2,EPS15L1,ZFYVE9,CLCN3,ABCG2,QKI,BTF3L4,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,ELAVL2,CERCAM,C3orf18,KATNAL1,F3,ACSL4,FKTN,POLR1B,SEC23B,CELF1,SALL3,GRB10,FICD,KCNB1,ARHGAP12,MBNL1,SESN3,NBL1,CNOT4,DDR2,PPARA,PXK,RAB5B,CEP97,PLEKHB2,RBBP6,UEVLD,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,SMOC1,CAMSAP2,ATMIN,SATB2,TCF7L2,PSD3,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,CSDE1,WIPF2,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-361-5p:TargetScan hsa-miR-361-5p TargetScan 3.01E-27 1.69E-23 6.88E-27 6.33E-26 59 214 "ADCY2,BEND6,MTUS1,ARHGAP20,DPP10,PKP4,CAMK2D,BRSK2,CBFA2T2,CFL2,B4GALT6,KIAA1549L,RCHY1,ERC2,CTNND1,MTX3,CALCRL,EPB41,RCAN2,GPHN,ERBB4,RRAGB,FOXM1,ANKFY1,FUT9,GPR75,PRUNE2,GPR22,HMGCR,HSP90AA1,KCNJ3,KCNN1,KIF5A,GPR155,MAP2,MDM4,MXI1,NFIA,ALDH1L2,NFIX,PBX1,PDE4B,PIK3R1,PKIA,PTPRG,GTDC1,EXD2,ALG9,SCAF8,RAB3GAP1,BDP1,FNBP1,CDK19,AJAP1,KLHL7,ARHGEF12,CSMD1,LYPD6,PARP11" MicroRNA hsa-miR-554:mirSVR_highEffct hsa-miR-554:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.53E-27 1.98E-23 8.06E-27 7.42E-26 76 351 "CLK4,SLC12A5,KIDINS220,AP1B1,GPR158,ABCD2,AMPD3,LRFN1,CDC42BPA,TMEM263,TTLL9,DST,CACNB2,THSD7A,MTMR7,CHM,TPP1,BTF3L4,FEZ1,CTNND1,HEPH,MAGI2,G3BP2,ABI1,EIF1,RCSD1,TOMM40L,ZNF589,ATP13A4,PDLIM5,DACH2,PPARGC1A,RND1,GLUL,KDM2B,ADAMTS8,PSIP1,SLC2A6,HSF2,RBPJ,IL6ST,INPP5B,KCNJ3,MYO9A,GPR85,PIK3R1,MINDY2,PTK2,RALGDS,FAT4,RGS12,SCN2A,TNFRSF19,ZFP30,CNKSR2,NLGN1,SEC31A,PREX2,LRRC55,ARHGEF40,CCDC88A,SMARCE1,RCOR3,KIF13A,SNRPN,PALLD,TEX2,NXT2,STAU1,UNC5D,RALYL,FAM200B,ACTR6,TMPO,ADAMTS9,URM1" MicroRNA hsa-miR-337-3p:PITA hsa-miR-337-3p:PITA_TOP PITA 3.56E-27 2.00E-23 8.12E-27 7.48E-26 56 193 "SORCS1,OSBPL8,ALCAM,APP,ZBTB10,WASF1,THSD7A,CAMK2G,AKAP5,ACBD5,SLC35F1,RBM39,APPL1,CTNND2,PUM1,FRMPD4,KCTD8,ABI1,E2F5,TENM1,EML1,ERBB4,NRN1,PSD2,PCDH11X,HLF,C5orf24,JAK2,KIF5C,LDLRAD3,MEF2C,MEIS2,NCAM1,CNOT4,NTRK3,PTPRN2,TTC13,ARID4A,ZFHX4,RORB,ATXN1,CPEB3,NTNG1,CCDC88A,SP4,LARP4,PRRC2C,SYN2,SYT1,CAMTA1,TCF4,EIF4ENIF1,TMEM237,SLC17A6,FXR1,FRMD6" MicroRNA hsa-miR-943:PITA hsa-miR-943:PITA_TOP PITA 5.16E-27 2.90E-23 1.18E-26 1.08E-25 51 160 "ASIC2,AMPH,NUMB,JAZF1,CALM1,CLTA,IQCK,CSNK1G3,ARHGEF4,CTIF,ARMCX2,CEP170,DLG2,CPEB2,HPCAL4,BRPF3,MSTN,RNPS1,TDRKH,SPACA9,MAEL,ELOVL5,HNRNPK,NEGR1,ZIC5,OLFM3,STXBP5,MBNL1,MBP,MYCN,NFIA,NOVA1,NRCAM,PDPK1,ENOX1,RDX,RGS7,RPL15,SCN2A,CPEB3,MAGI3,SLC1A2,BTBD7,FAM219A,KDM4C,ZNF384,TRPC1,TRIM9,SLC38A1,HNRNPA3,FRMD6" MicroRNA hsa-miR-147b:mirSVR_lowEffct hsa-miR-147b:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.42E-27 3.05E-23 1.24E-26 1.14E-25 74 336 "FAHD2CP,GPR158,PHYHD1,RGS9,ARHGEF7,BAIAP3,MMD2,VXN,CHGA,CASC2,TJP2,C4orf33,RAB26,SLC25A27,SH2B1,TENM4,PLXNA4,INTS1,TOMM20,ARRDC4,EPB41L1,MTSS1L,ANKRD13B,TOMM40L,FGFR1,IP6K2,SEMA4D,TVP23A,IP6K3,GHDC,ATP8A2,IGSF5,PPARGC1A,GLI2,GRM3,CIT,BTN2A1,TJAP1,MEIS1,MT3,PAX6,FTO,PMP22,PPP2R2C,WDR25,TMEM260,EML5,USP47,SUSD4,SLC6A15,GTDC1,RNH1,RPE65,ACER3,WLS,ZNF331,SCN8A,PRCD,SLC12A4,LGI3,MAPKBP1,SNRPN,SOX15,ZSCAN29,SYT5,SLC44A1,BHLHB9,DCBLD1,KCNE5,TMPRSS5,NSD2,SLC13A3,TRIM9,DOCK8" MicroRNA hsa-miR-615-3p:mirSVR_lowEffct hsa-miR-615-3p:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.80E-27 3.26E-23 1.32E-26 1.22E-25 71 311 "KCNH8,ZNF687,TMEFF1,RGS20,ASCL1,ASGR1,CACNB2,PTBP2,BRSK2,ASIC3,CASC2,RAB3C,SH2B1,NCOR2,RGS6,DCAF8,CHRDL1,DLG2,ATN1,EDN3,ELN,SPEG,RASL12,FLT1,TMEM107,ARFGAP2,LRRC37A6P,HEPN1,SPIN1,RABL2A,ADAMTS6,FRMD3,HTR2A,FAM95B1,SCIN,RTL5,NME4,DNHD1,NRGN,FAM216A,PLXNB3,POLR2F,PCDHB17P,VSTM2L,PRKCG,PRKCZ,BCAS3,SIDT1,FAM66C,DBX2,PRRT2,UBR7,CARF,BCAN,ABLIM3,SLC8A2,SLC20A2,KIF21B,IDI2-AS1,RGL1,AJAP1,DICER1-AS1,PIK3R5,TRO,CLIP2,SLC26A10,ZNF213,SEMA3B,TRIM16L,DOCK8,JPH3" MicroRNA hsa-miR-526b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-27 3.54E-23 1.43E-26 1.32E-25 63 247 "FAM43B,OGT,APBB2,LGR5,SEMA4G,ARSE,AP1M1,C1orf52,CDC25B,DLGAP2,CDR1,ZFYVE9,CLOCK,SUSD5,APPL1,SH3GLB1,ELAVL4,EPHB1,ST3GAL6,FGF1,SYNCRIP,SGIP1,FAM49B,STAMBP,CAB39,HBS1L,KIAA1841,GPR75,FUT10,GPR26,TPPP,KLHL23,LIFR,LOH12CR2,TM6SF1,XRRA1,CCDC80,TMOD2,PXK,ENOX1,ARMH4,AMER2,SLC30A10,ST6GAL1,RAB3GAP1,CXXC4,RCOR3,CDK19,FGD4,ASTN2,MGRN1,ACSL6,ZMAT3,HHIP,ARL10,TLR4,TRPS1,MEAF6,ZNF24,CADM2,KCNAB1,C12orf4,NETO2" MicroRNA hsa-let-7d*:mirSVR_highEffct hsa-let-7d*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.35E-27 3.57E-23 1.45E-26 1.33E-25 56 195 "CLK4,CDC7,BEND6,API5,DGKI,AKAP6,ARHGEF10,ERC2,TBC1D5,KIAA0753,RCAN1,MBNL2,ABI2,ABCA8,ANKFY1,UFM1,CAMKK2,NRG3,PHYHIPL,C15orf41,GLS,GNAO1,ZNF782,GUCY1B1,RASSF8,MIER3,SCRG1,HMGCR,LRRCC1,KCNC2,MAP4,MYCN,GPR88,PRTG,EPB41L4B,TATDN3,KANSL1,PRKACB,PTPRD,RAD52,FAM184A,RASGRF1,MRAP2,ZNF331,RADIL,NKAIN2,NXT2,SYN2,UNC5D,TCF7L2,TMPO,GUSBP1,KCNT2,PLPPR5,PARP11,RGS7BP" MicroRNA hsa-miR-1910-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.46E-27 3.63E-23 1.47E-26 1.35E-25 92 501 "SDE2,ABCF1,XKR4,PLEKHG5,ELFN2,PNMA8B,HECW2,TRMT9B,SHROOM2,ARHGDIA,DNAH17,ATM,BSN,DDR1,CANX,ISPD,CBFA2T2,DLGAP3,NRXN3,AKAP5,UBXN2A,PHF19,TMEM170A,DNAL1,EBI3,RASA4,MRNIP,MTSS1L,IGSF6,ANKMY1,KATNAL1,ZNF589,VTI1B,TRMO,TMEM151A,GABRB1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,FERMT2,KIF3A,KAT7,DDX19B,SCRG1,ZNF546,RBPJ,IBA57,COMMD5,CCDC80,NBL1,CNOT4,NUCB1,PDGFRA,CCSER2,PLXNB1,RETREG2,POLR2F,QDPR,RAB5B,PLEKHB2,ZNF793,ATXN1,SLC30A10,IL17RB,CPEB3,MYO18A,MAGI3,ATF7IP,SCN3B,KIF1B,ZSCAN29,NEK4,ACSBG1,SLC37A2,CAMSAP2,FAM208A,SATB2,NACC2,RBFOX2,TPM3,PPIL6,ZNF708,ZNF70,AMZ1,DPYSL5,EVI5,SNX27" MicroRNA "CAGCAGG,MIR-370:MSigDB" "CAGCAGG,MIR-370:MSigDB" MSigDB 7.32E-27 4.11E-23 1.66E-26 1.53E-25 49 148 "ABR,XKR4,MTUS1,TAOK1,PCDH10,OGT,ANK3,CNTNAP1,USP37,AQP4,CASK,CHRD,DDX3Y,SLC4A4,JAZF1,CACNG1,USP6,SRSF11,IFFO1,HDAC4,CTIF,GRIN3A,DSCAM,YAF2,PHF20L1,NCALD,PSD2,GABBR1,ZMYND11,CIT,KLF12,ZC3H12B,ING3,PPM1B,VSTM2L,RAP1GDS1,RGS3,PBRM1,STX1B,ATXN1,ST3GAL3,PKNOX2,IQSEC2,NFASC,NCDN,TPM4,KLC2,PARP6,PRDM10" MicroRNA hsa-miR-760:PITA hsa-miR-760:PITA_TOP PITA 7.43E-27 4.18E-23 1.69E-26 1.56E-25 58 210 "ANK1,LCORL,ARNTL,ATP2B1,ADGRB1,BCL2L2,CAMK2G,CANX,FMNL3,TMEM257,TAOK2,TJP2,SEC24C,RIMS4,PUM1,KIAA0513,WDR20,FAM107B,DLG3,CPEB2,HEYL,GOLGA7,RAB9B,SRRM1,CACNG3,FGF1,AKAP3,AHDC1,RND1,GRIN1,IL1RAPL1,MFSD2A,KCNMA1,MBNL1,MEIS2,GIT1,PABPC1L2A,SLC11A2,NTRK2,ZNF827,PRKAB2,FAM120C,GTDC1,SGK1,SHMT2,WDR37,SLC6A1,CCDC88A,SMARCE1,SNCB,HECW1,EPB41L3,STAC2,SMG6,TPM3,ZBTB38,DPYSL5,ST8SIA2" MicroRNA hsa-miR-4284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.81E-27 4.39E-23 1.77E-26 1.63E-25 106 642 "PLEKHH1,ESYT2,TBC1D14,TXNDC16,TAOK1,APAF1,CDC14B,KIAA1614,BMP7,NIPA1,FOXK1,MAP7,REPS2,DIS3L,ZFYVE9,AKAP5,CRY2,HINFP,APPL1,GREB1,FGFR1OP2,YTHDC1,GUCD1,KRBA2,HEYL,MRO,EIF5,TUBD1,PLEKHO1,EPB41,SLC43A2,IGSF6,SRARP,SCML2,POLR1B,FGFR1,AMOTL2,PCYOX1,CINP,APOPT1,PDLIM5,MSANTD4,GABRB3,TRAF3IP2,NCKAP1,CRCP,DBF4,RAB40B,GRK4,KIF3A,BVES,IRAK3,DDX19B,HMGB1,NEGR1,IGF1,IL6R,KCNJ5,KCNK2,LIMS1,MDM4,SAMD5,ZC3H12B,OLR1,PDPK1,ZNF655,STRN3,EXOSC10,APTX,PTAFR,MTMR10,PEX2,NWD1,C12orf49,ELP2,SNX22,DRAXIN,ZFP30,SH3BP2,R3HDM2,SLC1A2,ZNF430,SEPHS1,ZKSCAN3,INAVA,UHRF1BP1L,ZNF621,POGZ,SS18,ZSCAN29,KLHL7,ACSL6,TPCN2,SLC19A3,PCDHA6,ZNF106,ARL10,ZNF384,RFTN2,ZNF708,ZNF17,ZBTB16,LINC00632,FBXO36,ZDHHC20,NETO2" MicroRNA hsa-miR-891a:mirSVR_lowEffct hsa-miR-891a:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 8.05E-27 4.52E-23 1.83E-26 1.68E-25 74 338 "ADCY6,PWWP2A,KIAA1324,SEMA6A,GPRASP2,CNTNAP1,MIER1,RGS20,SYNJ1,CACNB4,VSTM2A,LOC730101,CCPG1,RAB28,PPT2,CNR1,LETMD1,IFFO1,NCOR2,TRIM69,MICAL2,PDE4DIP,ARMCX4,DUSP9,TSPAN5,SYT15,PHF20L1,SUGP2,EIF4G2,EIF5,ELAVL3,ELAVL4,F5,RACK1,CHST15,FGF1,CAMSAP1,FOXF2,C2orf88,EFCAB2,PDLIM5,TBR1,IP6K3,TCERG1,TOX3,ZNF638,LNX1,RNF165,HAS2,HMGCL,KCND2,A1BG-AS1,TM6SF1,HCN1,A2ML1,PPARA,PPP3CA,RANBP3L,CYBC1,RGS4,EPHA10,MCMBP,COPZ1,NTNG1,WDR47,SEPT8,CEP68,ARHGEF9,CRB1,CSMD1,LGI4,PCDH15,CAB39L,CAMK1G" MicroRNA hsa-miR-939:PITA hsa-miR-939:PITA_TOP PITA 8.70E-27 4.89E-23 1.98E-26 1.82E-25 39 90 "CSMD2,NDRG3,CASKIN1,CNIH2,SEMA4G,CADM3,ADGRB1,BCL2L2,CACNA1A,DCLK1,TAOK2,NRXN2,SLC35F1,DYRK1A,PHC2,ELN,ANKRD13B,AGAP3,USP21,CPLX2,GRIA1,GRIN2D,KAT7,KLF12,LRRC75A,CAMK2N2,MN1,GIT1,MSI1,ZNF827,PDE1B,MED1,PEAR1,SLC11A1,WDTC1,NFASC,NCDN,TCF7,SZT2" MicroRNA hsa-miR-335-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.44E-27 5.30E-23 2.14E-26 1.97E-25 70 305 "XKR4,RNF150,PCDH19,MARCH4,CADPS,CACNA1A,CACNA1E,C1orf52,FOXN3,ENTPD4,ANKRD44,VCAN,APPL1,PUM1,RIMS2,FAM107B,DYRK1A,TMTC1,YAF2,TENM1,RTN3,ZIC4,TAOK3,CAMSAP1,FOXF2,TMEM107,GALR1,NCKAP1,FAXC,SULT1C4,GFRA1,KCNMB4,GNAL,PRRC2B,ADAMTS8,RNF165,NEGR1,IL6R,KCND3,KCNN3,MBNL1,NFIA,NUCB1,GLIPR1L2,PAX6,PCSK2,ZNF426,SH3KBP1,POU3F2,PPARA,MDGA2,SH3TC2,BSDC1,ZMAT4,GTDC1,ACER3,SLC30A10,FAM126B,ZCCHC24,AJAP1,FGD4,FAM208A,KLHL4,CLDND1,ZNF24,KCNT2,ZNF225,SLC38A1,STMN4,NAV2" MicroRNA hsa-miR-623:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.57E-27 5.38E-23 2.17E-26 2.00E-25 62 241 "AS3MT,XKR4,ADCYAP1R1,SORCS2,AK2,SPOP,CACHD1,AQP6,ASGR1,BCL7A,BID,MYRF,CACNA1A,LURAP1,CAMK2G,SYT6,SLC16A4,DNAJB5,IPCEF1,CHD5,SPATA2,G3BP2,CHRDL1,FEM1B,AMOTL2,SRCAP,LILRA2,TPPP,NR3C1,PTPRT,KIF3A,PADI2,TLX1,EID2B,KLHL23,LSAMP,MDFI,MEIS1,NPTX1,PHKG1,KANSL1,MARCH1,SH3TC2,ZYG11B,DPF2,RORB,ELP2,TMEM156,ASIC4,MYO18A,BCAN,LRRC55,ZCCHC24,ZBTB43,SMOC1,ACSBG1,PRRC2C,TCF7L2,SEZ6L,TMEFF2,ZDHHC20,DPF3" MicroRNA hsa-miR-193b-3p:TargetScan hsa-miR-193b-3p TargetScan 9.75E-27 5.48E-23 2.21E-26 2.04E-25 58 211 "ANK3,BCL2L2,GPR146,DST,FUBP1,DDR1,CALB1,CALM1,RUNX1T1,KIAA1549L,SEC31B,CLOCK,FAM131B,CTIF,DBN1,DYRK1A,E2F6,ABI2,PLXNC1,EN2,ERBB4,ETV1,ANKFY1,PPARGC1A,GNAO1,CECR2,RFFL,ATOH8,ARHGAP19,KIT,LAMP2,MMP16,MYCN,NOVA1,PAK3,PPP2R5C,MAPK10,CNNM2,FAT4,MSANTD2,RFX3,LGR4,CSRNP3,ATXN1,CLSTN1,CXXC4,FAIM2,RGL1,GSE1,ARHGEF12,LRRC8A,DAAM2,DOK6,CADM1,BEST1,GDPD5,NAV3,ADAMTSL3" MicroRNA hsa-miR-193a-3p:TargetScan hsa-miR-193a-3p TargetScan 9.75E-27 5.48E-23 2.21E-26 2.04E-25 58 211 "ANK3,BCL2L2,GPR146,DST,FUBP1,DDR1,CALB1,CALM1,RUNX1T1,KIAA1549L,SEC31B,CLOCK,FAM131B,CTIF,DBN1,DYRK1A,E2F6,ABI2,PLXNC1,EN2,ERBB4,ETV1,ANKFY1,PPARGC1A,GNAO1,CECR2,RFFL,ATOH8,ARHGAP19,KIT,LAMP2,MMP16,MYCN,NOVA1,PAK3,PPP2R5C,MAPK10,CNNM2,FAT4,MSANTD2,RFX3,LGR4,CSRNP3,ATXN1,CLSTN1,CXXC4,FAIM2,RGL1,GSE1,ARHGEF12,LRRC8A,DAAM2,DOK6,CADM1,BEST1,GDPD5,NAV3,ADAMTSL3" MicroRNA hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 1.13E-26 6.36E-23 2.56E-26 2.36E-25 87 457 "SDE2,TMCC3,MTA3,ZNF608,OGT,EP400,ATM,ATP1A1,ATP2B1,BID,CFLAR,DST,ARHGEF1,BAG4,ACBD5,RBM39,PDE4DIP,KIAA0408,SCRN1,GIT2,ZBTB24,RHOBTB1,SACS,RABGAP1L,USP3,CPEB2,DYRK1A,EIF4G2,EIF5,ELAVL2,RGS17,DCTN4,TBC1D16,ST3GAL6,FKTN,FER,FOXO3,PNMA2,FAXC,MALT1,TNRC6A,MSL3,KIF3A,ZBTB45,EID2B,IGF1,SMAD1,MAT2A,ZNF680,BLOC1S2,PDE4B,OLA1,CAMKV,PIK3C2A,ZNF426,MTRF1L,PSAT1,RETREG2,PTPN13,NWD1,SLC25A36,ARMH4,SARS,LRRTM4,SFPQ,CPEB3,FBXO11,SEC31A,PPP4R3A,BTBD3,CPEB4,TMCC1,FAM126B,EPB41L3,DIP2A,DNMBP,ALG1,AGTPBP1,ASXL3,AMACR,SSBP2,TUB,UBE2H,SLC35A4,UBTF,WNK1,VANGL2" MicroRNA hsa-miR-320a:Functional MTI Functional MTI miRTarbase 1.18E-26 6.65E-23 2.68E-26 2.47E-25 100 584 "ADD1,UNC5A,TBC1D14,AK2,MARCH4,SEMA7A,EP400,TNRC6C,AQP4,ATP1A1,BTRC,CANX,ARHGEF2,KMT2C,ABCG2,DNAJB5,CHD1L,C2CD2,NCOR1,NOS1AP,EARS2,ZEB2,MED24,POM121,MED12,DPYSL2,TMTC1,EIF4G1,USPL1,EPB41,TUBA1B,PRMT5,SYNCRIP,FOXM1,SORBS1,USP16,GART,SRCAP,TNRC6A,GLUL,GNAS,GPT2,PSRC1,NUDT21,ZNF496,HMGB1,RBPJ,TJAP1,KITLG,MYO6,OCRL,OPA1,PKM,POLR2F,WBP1L,ANKHD1,SALL1,SBF1,ATXN1,HES6,SEC14L1,HSPA4L,FAM102A,CPEB3,SLC6A8,ATF7IP,SMARCC2,ERC1,ARHGAP26,TSPYL2,NXT2,MAPK8IP3,NSFL1C,ZC3H4,PRRC2C,TAC1,TAL1,SATB2,USP22,ARL10,CBX5,TMPO,R3HDM1,CABIN1,TPD52,SMUG1,PDSS1,TSC1,TUB,VAV2,SF1,ZFP37,ZIC2,ZFAND5,SMARCAD1,INTS3,WNK1,CSDE1,RNF103,RTN4" MicroRNA hsa-miR-101-3p:Functional MTI Functional MTI miRTarbase 1.22E-26 6.85E-23 2.76E-26 2.54E-25 80 393 "ARID1A,CDC7,TRMT9B,LRCH2,GPAM,APP,ATM,STX16,BTRC,INA,CBFA2T2,C1orf52,CD81,CPS1,SPATA2,ZEB2,BLOC1S6,ZC3H11A,RAB39B,MBNL2,GOLGA7,EIF4G2,ELAVL2,PLEKHA1,ELAVL3,MTSS1L,EYA1,ANKFY1,STAMBP,NCKAP1,DIDO1,GRIK3,DDX19B,KLF12,ZDHHC15,HSP90AA1,DIPK1A,JAK2,KLHL23,STMN1,LIFR,MBNL1,MEIS1,MITF,MKLN1,MRPL42,MYCN,MYO9A,PABPC1L2A,NACA,NAP1L1,SLC11A2,CHAMP1,ZNF827,PAK3,PIK3CD,PPP2R5E,QDPR,PGBD4,FBXW7,RMI1,ATXN1,FBXO11,FNDC3A,TRERF1,ITPRID2,NXT2,ZEB1,DICER1,TGFBR3,TSN,CADM1,RPL7L1,WNT7A,SPIRE1,WNK1,MPPE1,RTN4,FRMD6,GAN" MicroRNA hsa-miR-519a-3p:Functional MTI Functional MTI miRTarbase 1.27E-26 7.15E-23 2.88E-26 2.65E-25 75 349 "ADAR,ADARB2,TAOK1,SEMA7A,CAPRIN2,NIPA1,MAP7,CFL2,EPS15L1,ZFYVE9,CLCN3,QKI,BTF3L4,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,ELAVL2,CERCAM,C3orf18,KATNAL1,F3,ACSL4,FKTN,POLR1B,SEC23B,FOXF2,CELF1,SALL3,GRB10,FICD,KCNB1,ARHGAP12,MBNL1,SESN3,NBL1,CNOT4,DDR2,PXK,RAB5B,CEP97,PLEKHB2,RBBP6,UEVLD,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,SMOC1,CAMSAP2,ATMIN,SATB2,TCF7L2,PSD3,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,CSDE1,WIPF2,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-1468:mirSVR_highEffct hsa-miR-1468:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-26 7.84E-23 3.16E-26 2.91E-25 77 367 "NBAT1,ADD3,SORCS1,CEP126,AMPD3,LCORL,CALB1,CAMK2D,CAMK2G,ZNF501,LRRFIP1,CFL2,CLCN3,TBPL1,UBXN2A,CTH,EDRF1,TCAF1,KIAA0753,SV2A,DMTF1,DTNA,DNM1L,EDNRB,ATL1,FCF1,MBNL2,OLIG2,ABCA8,ATP8A1,MEX3B,ZMYND15,NOP56,NELFCD,C2orf88,TVP23A,ZNF512,GLS,HTATSF1,PTPN5,IGFBPL1,ZNF678,LAMP2,VWA5A,SRSF12,SCG3,NCAM1,OPA1,PIK3CD,JAKMIP1,NXPH1,PTN,TMEM255A,TRIM68,PRRT2,RGS7,TMEM206,SPIN3,MCMBP,SOX8,ITSN1,SYBU,NLGN1,ST3GAL3,FAM81A,SOX2,ADAMTS17,TCEA1,C5orf64,NEIL2,PLEKHH2,USP1,MEAF6,WIPF1,TRIM9,FTSJ1,ZDHHC20" MicroRNA hsa-miR-7160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-26 8.06E-23 3.24E-26 2.99E-25 90 487 "TTYH1,ABCF1,AS3MT,NDRG3,TXNDC16,APAF1,AQP6,CDC14B,SFMBT2,ATM,ZNF583,ZNF555,PTBP2,FMNL3,SLC16A4,CBFA2T2,GPR37L1,NRXN3,SUMF2,MFSD4A,SLC35F1,IPCEF1,KIAA0408,KIAA0513,IST1,TMEM170A,TOMM20,ELMSAN1,SV2B,SGSM2,DNAH9,SLC29A4,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,EIF1,VPS26C,ZNF585B,ZNF589,ATP13A4,MSANTD4,CRCP,GPR75,GLUL,ZNF638,KIF3A,BVES,AGBL5,IGF1,KLHL23,SMAD9,MATN3,PPM1L,SLC11A2,EPB41L4B,MTMR10,TMEM145,QDPR,RAB5B,PLEKHB2,ALG9,GSTCD,PTGR2,SH3BP2,SLC2A5,PEX26,EPN2,SEPHS1,WDTC1,CDK19,MCF2L2,LHPP,ZSCAN29,FAM208A,SLC19A3,AKNA,PCDHA6,ARL10,TPM3,SSBP2,USP1,EVI5,SNX27,ITM2C,WIPF2,MPPE1,ZDHHC20" MicroRNA "CTACTGT,MIR-199A:MSigDB" "CTACTGT,MIR-199A:MSigDB" MSigDB 1.49E-26 8.39E-23 3.38E-26 3.11E-25 52 170 "PLEKHH1,ARHGAP20,DPP10,ANK2,PHF12,LRRC4C,ASCL1,SLC4A4,NRP2,BRSK2,DGKI,CDC42,QKI,ARHGAP24,DLG3,TSPAN5,CALCRL,KCNMB2,ETV1,FGF12,SEMA6C,PSD2,TACC2,GABRA4,ZNF638,GPM6A,EML4,PTPN5,FAM222A,ZHX1,KCNK1,LIFR,HECTD2,MAP6,MBNL1,MEIS2,NFE2L2,NOVA1,PDGFRA,NXPH1,PPP2R5E,PTX3,BTBD7,CPEB4,SORCS3,KDM3A,TAB2,CAMTA1,CDH22,VLDLR,ADAMTSL3,FXR1" MicroRNA hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA_TOP PITA 1.56E-26 8.78E-23 3.53E-26 3.25E-25 62 243 "OGT,PKP4,DDX3Y,ATP1A2,NOL4,FOXK1,PTBP2,CAMK2G,USP6,COL9A1,BTF3L4,CS,AATK,SOCS5,ST18,DGKG,SCRN1,SMG7,G3BP2,MBNL2,COPS4,EPB41L2,RCAN2,SRRM1,FOXO3,AFF2,HBS1L,PCDH17,PRRC2B,GPD2,FAM19A2,SOX21,CELF5,SMAP1,MEIS1,MYCN,ZC3H12B,NEUROD1,PCDH8,PDE1C,EPN1,NUDT11,SCN2A,ITSN1,R3HDM2,WDR37,PPP4R3A,CPEB4,TMCC1,SOX2,MYCBP2,SRPK2,SSTR2,PLCB1,SYN2,PSD3,PUM2,CSMD1,CSDE1,NAV3,MSRB3,RNF146" MicroRNA hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 1.57E-26 8.81E-23 3.54E-26 3.26E-25 84 431 "ACLY,GPRIN1,PLEKHG5,APC,BACH1,BCL2L2,BMPR1B,MTMR3,FMNL3,SLC16A4,LONRF2,ZNF385A,NCOR2,RIMS4,MATR3,IP6K1,MYEF2,CEP170,RASGRP1,SUGP2,EGFR,EIF5,ERBB2,CD320,C2orf88,TACC2,SMC2,NPTN,DKK3,GABRB3,HBS1L,ZMYND11,ACSS1,MUM1,MAN1B1,HNRNPK,NEGR1,IL6R,JAK2,SLC35G1,LIFR,LSS,PTOV1,NRDC,NTRK3,OPRL1,PIK3CD,PKM,HMGCLL1,MTRF1L,STRN3,PSAT1,DRAM2,MED1,PTH1R,C1orf109,HKR1,UBR7,RNH1,ATXN1,CASC3,COPZ1,R3HDM2,BTBD3,ABTB1,EMC1,GANAB,EXOC7,FAM208A,TMEM136,PCDHGB2,CRTC1,TMEM9,HSPBP1,SLC35A4,BCL2L13,KLC2,ZNF177,DHX33,WNK1,STOX2,SMIM8,TMEM63C,FXR1" MicroRNA hsa-miR-504-5p.1:TargetScan hsa-miR-504-5p.1 TargetScan 1.58E-26 8.88E-23 3.57E-26 3.29E-25 54 184 "CPNE2,GRAMD1B,PCDH19,KCTD16,ANK3,ANXA7,BCL2L2,PTBP2,RUNX1T1,FMNL3,LRRFIP1,DLGAP2,NIPBL,IGLON5,CNTFR,ARMC8,NCOR2,PLXNA4,RIMS3,GRIN3A,ELAVL4,RCAN2,EYA1,HPCAL4,FLT1,ATP8A2,MMADHC,KCNMB4,ATCAY,KCNJ11,KCNK3,KPNA5,SAMD14,NOVA2,HCN1,PKD1,FTO,RPRD1A,CYB561D1,RORB,EPHA10,RPL15,CSRNP3,MAPKBP1,LHFPL4,ANKRD12,CNTN2,KIAA0930,NSD1,ASXL3,RBFOX2,NR2C2,BEST1,KLC2" MicroRNA hsa-miR-3653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-26 9.08E-23 3.65E-26 3.36E-25 104 627 "AS3MT,TMEM132B,ELFN2,RNF157,TAOK1,CDC14B,SLC7A14,KIAA1614,ATM,SLC4A4,ALDH7A1,BCL2L2,CACNB2,STOML1,CREM,ENTPD4,HINFP,CSNK1E,RIMS4,KIAA0408,MYADM,DNAL1,RABGAP1L,WDPCP,CNNM1,MRNIP,RGS17,PLEKHO1,SLC43A2,FKTN,FDFT1,FOXO3,AFF2,TMEM151A,NCKAP1,SRCAP,CRCP,KIAA1958,CNDP1,GRK4,KIF3A,RNF165,HAS2,DDX19B,HMGB1,ZDHHC15,ATCAY,EID2B,C2orf72,METTL21A,KCNN1,KCNN3,NCOA7,MAN2A2,CHST6,P2RX7,TMOD2,PIK3C2A,EPDR1,APTX,PIGG,ZSCAN2,TMEM231,ZNF844,NWD1,GTDC1,DCUN1D2,PGBD4,UEVLD,FAM192A,SCN2B,HSPA4L,ZFP30,NUBPL,PEX26,ZNF430,ZNF667,ANKRD36,FAM126B,CLUAP1,ZBTB43,SSTR2,MPRIP,STAC2,AGTPBP1,SATB2,TPCN2,PCDHA6,ZNF34,ZNF106,ARL10,ERCC6L2,SGK3,USP1,MEAF6,AGMO,ZNF70,ZBTB16,LMAN2L,WIPF2,MPPE1,PHTF2,SSPN,GAN" MicroRNA hsa-miR-6758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-26 9.57E-23 3.84E-26 3.54E-25 64 259 "ADD2,CASKIN1,HACE1,SORCS2,TAOK1,TRMT9B,CDC42BPA,SFMBT2,IGDCC4,BACH1,BCL7A,ZFYVE9,ARHGEF6,MICAL2,PDE4DIP,SEC14L5,TM9SF4,IP6K1,DNAL1,CHRDL1,MAMLD1,E2F6,APH1A,ABI2,EPB41L1,PCYOX1,AFF2,HHIPL1,GAP43,SRCAP,TNRC6A,B4GALNT4,GRID1,RABL2A,SHISAL1,SLC6A17,MAG,HS6ST3,ZC3H12B,NFIX,KSR2,ZNF827,PDE4A,PFKFB3,CDK14,PKM,PTPRB,NKAIN1,RAB5B,FIGN,PTGR2,STX1B,NCBP3,AMBRA1,SEPHS1,PALLD,WDTC1,SEPT8,NSD1,TUBB2A,ZNF70,SIGLEC10,NAV2,PIANP" MicroRNA hsa-miR-301a-3p:Functional MTI Functional MTI miRTarbase 1.74E-26 9.75E-23 3.91E-26 3.61E-25 80 395 "ADARB2,TAOK1,ABCD2,PHF12,CAPRIN2,STX16,NIPA1,MAP7,CFL2,ZFYVE9,CLCN3,TPP1,QKI,BTF3L4,ACBD5,LONRF1,DAPK1,CEP170,SEC16A,DPYSL2,EDN1,TMTC1,CERCAM,C3orf18,ACSL4,DLC1,FKTN,POLR1B,SEC23B,CINP,MSANTD4,SALL3,GPR75,TNRC6A,PRUNE2,LILRA2,GRB10,ZIC5,ZNF678,KCNB1,ARHGAP12,MBNL1,CHIC1,CNOT4,NPTX1,PURG,PIGG,PXK,PTPRG,RAB5B,PTGR2,CLIP1,BTBD3,ATF7IP,KIF13A,CDK19,SPART,TROVE2,POGZ,SMOC1,SSTR2,ERBIN,CAMSAP2,ATMIN,SATB2,TCF7L2,DICER1,GPR161,ZMAT3,THRA,NACC2,TRPC3,UBC,ZNF711,ZNF24,ZNF154,MFF,WIPF2,WNK3,FXR1" MicroRNA hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 1.83E-26 1.03E-22 4.12E-26 3.79E-25 87 460 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,MBNL2,ABI2,IRAK4,ELAVL2,BSCL2,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,LEFTY2,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,TRPS1,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 1.83E-26 1.03E-22 4.12E-26 3.79E-25 87 460 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,HDAC4,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,EGFR,ABI2,IRAK4,ELAVL2,BSCL2,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,NFIA,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-122-5p:Functional MTI Functional MTI miRTarbase 2.24E-26 1.26E-22 5.05E-26 4.65E-25 102 609 "ABCF1,CLK4,XKR4,ADCY2,RNF157,ESYT2,HECW2,KIF6,ANK2,EP400,USP28,ANXA7,CPNE5,ATP1A2,DOCK11,BCL2L2,WASF1,ISPD,SPAG9,NUMBL,FBXO7,CNN3,AKAP5,ENTPD4,CS,PHF14,PYGO1,IST1,DBT,KRBA2,OPTN,EGFR,TUBD1,TMEM74,KATNAL1,SEC23B,CINP,SPECC1,STAU2,GPR75,TNRC6A,GLUL,CNDP1,LILRA2,KAT7,IBA57,LIMS1,GPR155,MDM4,MKLN1,NASP,NCAM1,NODAL,SLC11A2,OLR1,PFKFB2,OLA1,NLGN3,NALCN,ZNF655,PKM,GPSM2,PMP22,PIGG,ZYG11B,PGBD4,SNX22,PTGR2,NCBP3,SCN4B,GALNT10,HSPA4L,FAM102A,SLITRK3,SLC15A2,ANKRD36,SOX2,NMNAT2,ERC1,PEG10,CDK19,SSTR2,NCDN,MPRIP,KLHL7,ALG1,WWC1,TMEM136,VWC2,GPR161,ZNF106,SLC44A1,TPD52L2,UBTF,OSBP2,MEAF6,ZNF74,ZNF154,PARP11,TIGD6,RNF170,CPNE4" MicroRNA hsa-miR-4635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-26 1.35E-22 5.41E-26 4.98E-25 73 335 "FAM43B,TMCC3,KIAA1211,ANK1,PARG,TNRC6C,SEMA4G,AP1M1,CACNB2,CANX,DGKI,DLGAP2,CLCN3,ABCG2,CLOCK,PHF14,PITPNC1,MYEF2,KLHL3,CALN1,SH3GLB1,ELAVL4,RGS17,NCALD,FER,POLR1B,FAXC,CRCP,FUT10,TPPP,ATCAY,KCNN3,CREG2,LIFR,TM6SF1,CCDC80,MTR,CLDN11,PCDH9,TMOD2,HMGCLL1,MAPK9,PTAFR,NCR3LG1,KLHL11,ZNF568,AMER2,ATXN7,FNDC3A,NUBPL,CPEB4,NAXD,CXXC4,RCOR3,ANKRD36,FNBP1,KIF1B,SSTR2,ERBIN,SULF2,KLHL7,TMEM136,PCDHA6,ZNF106,CBX5,HEY2,TPM3,ZKSCAN5,MEAF6,ZNF225,MPPE1,C12orf4,GAN" MicroRNA hsa-miR-490-5p:PITA hsa-miR-490-5p:PITA_TOP PITA 2.43E-26 1.36E-22 5.46E-26 5.03E-25 48 145 "TAOK1,MARCH4,FAM135A,USP37,SYNJ1,TMEM257,CDH2,CNOT8,CREB5,ATRNL1,PLCXD3,TOX,CTIF,SRGAP3,DPP6,EGR3,PRKAG2,AFF2,MSTN,TOX3,FERMT2,GRIA2,MIER3,ZIC5,KIAA1755,KCNA1,MAT2A,CHIC1,NTRK2,CCSER2,WBP1L,TMEM260,PTPRD,ROBO1,LRFN5,FAM102A,FNDC3A,BTBD3,CCDC88A,SOX2,ZNF423,ARHGAP26,SYT11,SZT2,TRPS1,ZIC1,SNX27,FRMD6" MicroRNA hsa-miR-433:PITA hsa-miR-433:PITA_TOP PITA 2.54E-26 1.43E-22 5.71E-26 5.26E-25 62 245 "XKR4,CSMD3,INTS2,HECW2,PCDH19,ZBTB10,BTRC,USP6,MAGI1,FOXN3,NMT2,QKI,HP1BP3,CEP170,SACS,WDR20,RAB39B,ABI1,RBM12,YAF2,COPS4,ERBB4,ETV1,PRKAG2,ST6GALNAC3,OGA,STAG2,HBS1L,PPARGC1A,PCDH11X,FERMT2,EML4,KLF12,NEGR1,IGFBP1,KCNMA1,SESN3,MXI1,GPR137C,NXPH1,MED1,PPP3CB,MAPK9,MTMR10,TTC13,RAP1GDS1,PBRM1,FBXW7,CLIP1,CSRNP3,CHD9,EPN2,PDZRN3,VPS13A,ANKRD12,CAMTA1,FAM208A,TRIM2,TJP1,TSC1,PLEKHH2,STMN4" MicroRNA hsa-miR-519b-3p:Functional MTI Functional MTI miRTarbase 2.58E-26 1.45E-22 5.79E-26 5.33E-25 74 344 "ADAR,ADARB2,TAOK1,SEMA7A,CAPRIN2,NIPA1,MAP7,CFL2,EPS15L1,ZFYVE9,CLCN3,QKI,BTF3L4,UBXN2A,FBXL5,SEC16A,NR1D2,DPYSL2,DNAJB6,FEM1B,TMTC1,APH1A,ELAVL2,CERCAM,C3orf18,KATNAL1,F3,ACSL4,FKTN,POLR1B,SEC23B,CELF1,SALL3,GRB10,FICD,KCNB1,ARHGAP12,MBNL1,SESN3,NBL1,CNOT4,DDR2,PXK,RAB5B,CEP97,PLEKHB2,RBBP6,UEVLD,ATAT1,TMEM200C,MAPKBP1,KIF13A,POGZ,SMOC1,CAMSAP2,ATMIN,SATB2,TCF7L2,PSD3,DICER1,ARL10,NACC2,NR2C2,UBC,UBTF,ZNF70,EMSY,MFF,CSDE1,WIPF2,WNK3,PHTF2,ZDHHC20,NETO2" MicroRNA hsa-miR-150:PITA hsa-miR-150:PITA_TOP PITA 2.61E-26 1.46E-22 5.85E-26 5.39E-25 56 200 "APC,CACNA1G,BSN,CAST,ZMYM4,RIMS2,ELMSAN1,C2CD2L,KLHL3,POM121,NR1D2,DYRK1A,KMT5B,PLXNC1,KCTD3,EIF5,EPB41,TESK2,CAMSAP1,NBEA,GABRG2,PPARGC1A,GLDC,TNRC6A,RNF165,NEGR1,KCNN3,IPO5,NFIX,NKX2-2,NRCAM,NLGN3,SEMA5B,FTO,MAPK9,PTCH1,PTPRB,PRRT2,SETD5,RORB,PPM1E,CPEB4,TMCC1,SOX11,ERC1,RAP1GAP2,LRRC4,FBXW11,ZEB1,TRPS1,ZNF189,MAP3K12,HRASLS,KAT6A,PHTF2,RNF146" MicroRNA hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA_TOP PITA 2.62E-26 1.47E-22 5.89E-26 5.42E-25 51 165 "ADD1,MAP4K3,SHTN1,JAZF1,FOXN3,QKI,TOX,SNAP91,DLG3,NR1D2,CPEB2,ABI1,EIF4G2,KIAA1109,MEX3B,ANKFY1,PCDH11X,ATF7,PSIP1,BACH2,MIER3,HMGB1,TUBB2B,KTN1,MBNL1,MEF2C,NEUROD1,PCDH9,CDK14,MED1,KANSL1,OXR1,RET,ZFHX4,SCN2A,LRRTM4,CPEB3,FAM81A,TET1,ERBIN,SYPL1,TCF4,SATB2,SLC44A1,ZFP91,HEY2,PLEKHH2,ZNF24,GOPC,PAK5,HNRNPA3" MicroRNA hsa-miR-6856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-26 1.49E-22 5.95E-26 5.48E-25 63 253 "ADD2,CASKIN1,HACE1,SORCS2,TAOK1,TRMT9B,CDC42BPA,SFMBT2,IGDCC4,BACH1,BCL7A,ZFYVE9,ARHGEF6,MICAL2,PDE4DIP,SEC14L5,TM9SF4,IP6K1,DNAL1,CHRDL1,MAMLD1,E2F6,ABI2,EPB41L1,PCYOX1,AFF2,HHIPL1,GAP43,SRCAP,TNRC6A,B4GALNT4,GRID1,RABL2A,SHISAL1,SLC6A17,MAG,HS6ST3,ZC3H12B,NFIX,KSR2,ZNF827,PDE4A,PFKFB3,CDK14,PKM,PTPRB,NKAIN1,RAB5B,FIGN,PTGR2,STX1B,NCBP3,AMBRA1,SEPHS1,PALLD,WDTC1,SEPT8,NSD1,TUBB2A,ZNF70,SIGLEC10,NAV2,PIANP" MicroRNA hsa-miR-1321:PITA hsa-miR-1321:PITA_TOP PITA 3.43E-26 1.93E-22 7.71E-26 7.10E-25 56 201 "ASIC1,KLHL13,CADM3,CAMK2G,RUNX1T1,DLGAP2,NRXN2,PICK1,CREB5,MICAL2,AIF1L,DBN1,DLG3,DNM1,SEZ6L2,GPR61,ELAVL3,NRN1,AGAP2,JPH4,RND1,GRIK2,RNF165,LRRTM1,NAT8L,MAT2A,NFIX,NOVA2,OMG,PENK,PURG,PMP22,PRRX1,RETREG2,MED1,PTK2,PTPRO,RAP1GDS1,PRRT2,RTKN,ATXN2,COPZ1,WDR47,FAM214B,SOX11,SS18,CBX5,TPM3,SSBP2,UBE3A,AMOT,MEIS3,RNF103,SNX27,KCNAB1,KAT6A" MicroRNA hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 3.71E-26 2.08E-22 8.32E-26 7.66E-25 86 455 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,APP,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,ABI2,EIF4G1,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,SIRT1,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-628-3p:PITA hsa-miR-628-3p:PITA_TOP PITA 4.56E-26 2.56E-22 1.02E-25 9.42E-25 50 160 "PCDH19,AMPD3,SYNJ1,BTK,JAZF1,PTBP2,SEPT7,MAP4K4,BTF3L4,SLC35F1,GAPVD1,FRMPD4,DLG2,DYNC1I1,FRY,FSD1L,YAF2,PAN3,AFF2,PCDH17,GPM6A,EML4,KLF12,MIER3,HLF,NEGR1,ZIC5,PACRG,MID1,HS6ST3,NEXMIF,PCDH9,EPB41L4B,PPP3CA,PPP3CB,PBRM1,ATXN1,SLC8A1,TET1,SPTB,NKAIN2,SYT4,TCF7,HHIP,RIMBP2,RBFOX2,TRPS1,HEPACAM,FAM155A,PAK5" MicroRNA "CCCAGAG,MIR-326:MSigDB" "CCCAGAG,MIR-326:MSigDB" MSigDB 4.85E-26 2.73E-22 1.09E-25 1.00E-24 48 147 "RALGAPA1,OGT,ATP2B2,CACNA1E,DLGAP2,WHRN,CSNK1G3,RIMS4,KIAA0513,COPS7A,NCALD,CORO2B,ANKFY1,BRPF3,ARPP21,GGT7,HPGDS,GNAO1,DIDO1,ADAMTS6,LRRTM1,PALM,KCTD15,PURG,PPP3CB,PKIA,BSDC1,DUSP15,KCNIP2,SEMA6D,ATXN1,ITSN1,PPM1E,FNDC3A,ST3GAL3,BTBD3,EPN2,SLC8A2,INAVA,SNCB,FAIM2,TCF4,AHCYL2,CDH22,VLDLR,NAV3,PPP1R3F,ST8SIA2" MicroRNA hsa-miR-3193:mirSVR_lowEffct hsa-miR-3193:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.96E-26 3.35E-22 1.34E-25 1.23E-24 79 393 "RALGAPA1,NCKAP5,SLITRK1,NLGN4X,AP1B1,C1QTNF3,ALAD,NCOA1,B3GALT2,NRP2,LINC00906,METTL6,P2RX6,CD38,ZBED1,CHM,CPNE6,SUMF2,AHCTF1,ZNF521,SLC35F1,RASGEF1C,PLCXD3,CTH,FAM131B,RIPOR2,HDAC4,SIRPA,COPS7A,NTM,DLG4,OLIG1,CD99L2,SLC29A4,DTNA,PHF20L1,APH1A,SRRM1,FCGR1A,NELFCD,TUBA8,GGT7,MSL3,GPR12,ARHGAP19,GAREM2,KNDC1,IPO5,MT3,MYO7A,NINJ2,NME4,KCNK10,POU3F2,PPP1R1A,PPP2R2C,NDUFS7,SNRK,NKAIN1,FAM66C,ROGDI,RASGRF2,RNF220,RNASE1,EPHA10,MEG3,WLS,SARS,ANKRD6,NMNAT2,NFASC,SYT11,UNC5D,BHLHB9,ZIC1,NDRG4,ZNF138,FAM219B,RNF170" MicroRNA hsa-miR-10b-5p:Functional MTI Functional MTI miRTarbase 6.62E-26 3.72E-22 1.48E-25 1.37E-24 71 323 "ACLY,ADRA1B,SLC24A4,TXNDC16,C6orf89,ANXA7,API5,STK33,NRP2,USP6,ZNF445,CRY2,NCOR2,IPCEF1,USP6NL,CENPL,TMEM170A,MTX3,DLX1,USP3,AASDH,FEM1B,FAM13A,MBNL2,EIF1,TUBA1B,ZMYND11,GK,MSL3,LILRA2,PTPRT,SYNPO,IGSF1,OLFM3,LSS,MBNL1,NAP1L1,NF1,NPTX1,SLC11A2,PAX6,PIK3CD,PPARA,PPP3CB,PSMD13,DPF2,KLHDC8A,NCBP3,FOXRED2,CSRNP3,TRA2B,KIF21A,URGCP,SCMH1,SON,SYT11,PRRC2C,DDHD2,FAM208A,ZEB1,TRIM2,AHCYL2,HHIP,TIAM1,CSMD1,TPM1,TPM4,NR2C2,RUNDC3B,CADM1,ZNF708" MicroRNA "ACAACTT,MIR-382:MSigDB" "ACAACTT,MIR-382:MSigDB" MSigDB 7.35E-26 4.13E-22 1.65E-25 1.52E-24 34 69 "NDRG2,MTUS1,AQP6,DDX3Y,EIF4G3,ATP2B1,BACH1,CLTC,SEC24C,MATR3,MBNL2,EN2,NSRP1,AMOTL2,NEGR1,MBNL1,MMP16,NFIA,P2RX7,PDPK1,PPP3CC,RPE,SGK1,BTBD7,SORCS3,SYT1,CAMTA1,ZNF106,UBE2H,PLPPR2,SMARCAD1,SYNC,HPS4,SLC17A6" MicroRNA hsa-miR-1193:TargetScan hsa-miR-1193 TargetScan 7.55E-26 4.24E-22 1.69E-25 1.56E-24 60 234 "ESYT2,LRFN1,CASK,ATP1A2,ATP6V0A1,BCL7A,CACNA2D1,DIRAS1,P2RX6,CBFA2T2,REPS2,LRRFIP1,KIAA1549L,CRY2,MATR3,IP6K1,ELMSAN1,DNAJC6,CEP170,GNE,ABI2,EGR3,RGS17,PLEKHO1,EZH1,BRPF3,GPD1,GPR26,NXPH3,NEGR1,AGFG1,MSL1,IGF1,KCNB1,LSAMP,GPR155,MMP16,NHLH1,NOVA1,NOVA2,HCN1,PBX1,PDE3B,PRKACB,RAB5B,ACER3,MYO18A,MBD5,KIF21B,AJAP1,MMS19,KLHL4,AHCYL2,HIF3A,AP4E1,HHIP,FBXL16,CBX5,DAAM2,HNRNPA3" MicroRNA hsa-miR-758:PITA hsa-miR-758:PITA_TOP PITA 7.86E-26 4.41E-22 1.76E-25 1.62E-24 49 155 "ABAT,INTS2,CDC42BPA,MAP4K3,DDX3Y,ATP2B2,BMP7,RUNX1T1,MAGI1,QKI,MAP4K4,APPL1,DLG2,RASGRP1,CLVS1,SPSB4,NBEA,APOPT1,TVP23A,SRRM4,BACH2,HLF,MEIS2,NEUROD1,PLP1,ANKRD16,STRN3,POU3F2,RELN,SYTL2,OXR1,SLC6A15,ZC3H14,ATXN1,CPEB4,STXBP1,UNC5D,CUX2,PUM2,ZFPM2,TIAM1,CADM1,ZBTB38,REEP1,EMSY,CSDE1,RNF103,FRMD6,SLC4A10" MicroRNA hsa-miR-375:TargetScan hsa-miR-375 TargetScan 8.02E-26 4.50E-22 1.79E-25 1.65E-24 58 219 "ASCL1,EIF4G3,DPY19L3,CDK5R1,DST,LDLRAD4,CAST,KCNAB3,KIAA1549L,QKI,PLXNA4,MATR3,KLHL3,DLG3,ABI2,ELAVL2,ELAVL3,ELAVL4,EIF1,EPB41L2,PIPOX,NBEA,GALNT15,C15orf41,GRIK2,GRM5,RASSF8,HAS2,KLF12,BACH2,MIER3,RBPJ,INSM1,JAK2,KCNJ3,MBNL1,MEIS1,MSI1,MXI1,MYO9A,NFIA,NFIX,PAX6,PDE3A,PDE4D,PDPK1,PACSIN1,CEP41,ANKHD1,GTDC1,RORB,AP1AR,ATXN1,ATXN7,SCN2B,ERC1,ARHGEF12,CADM1" MicroRNA hsa-miR-208a-3p:TargetScan hsa-miR-208a-3p TargetScan 8.65E-26 4.86E-22 1.93E-25 1.78E-24 50 162 "KCTD16,OSBPL1A,LRCH2,APC,DDX3Y,MTMR3,PTBP2,CDC27,CDH2,CFL2,RAB3C,QKI,HDAC4,SCRN1,HP1BP3,MTX3,ABI1,EBF1,EIF4G2,EIF5,ELAVL2,ELAVL4,EPHA5,FOXG1,GABRA1,AHCYL1,FAXC,GLYR1,EML4,IL1RAPL1,LRRTM1,KCNN3,MEIS1,MMP16,NOVA1,CDK14,PPP3CB,PTPRG,SATB1,SCN2B,FNIP1,CHD9,FNDC3A,CNKSR2,RIMS1,POGZ,LRRC8A,REEP1,ANKS1B,NAV2" MicroRNA hsa-miR-208b-3p:TargetScan hsa-miR-208b-3p TargetScan 8.65E-26 4.86E-22 1.93E-25 1.78E-24 50 162 "KCTD16,OSBPL1A,LRCH2,APC,DDX3Y,MTMR3,PTBP2,CDC27,CDH2,CFL2,RAB3C,QKI,HDAC4,SCRN1,HP1BP3,MTX3,ABI1,EBF1,EIF4G2,EIF5,ELAVL2,ELAVL4,EPHA5,FOXG1,GABRA1,AHCYL1,FAXC,GLYR1,EML4,IL1RAPL1,LRRTM1,KCNN3,MEIS1,MMP16,NOVA1,CDK14,PPP3CB,PTPRG,SATB1,SCN2B,FNIP1,CHD9,FNDC3A,CNKSR2,RIMS1,POGZ,LRRC8A,REEP1,ANKS1B,NAV2" MicroRNA hsa-miR-6760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.91E-26 5.00E-22 1.99E-25 1.83E-24 59 227 "DPF1,ELFN2,KIF6,PPFIA3,SEMA4G,FOXK1,HAP1,CANX,ARHGEF6,RGS6,MICAL2,KIAA0513,TM9SF4,IP6K1,ELMSAN1,CHRDL1,FGFR1,ANKFY1,GFRA1,GLYR1,IDH3A,SLC6A17,MDFI,SAMD14,NBL1,ZC3H12B,NDUFA5,PDE4A,GPR173,KCTD15,PTPA,SLC22A23,NKAIN1,RAB5B,MORC4,RNH1,MYH14,RTKN,CCDC88A,SLC11A1,WDTC1,SP2,ERC1,NEK4,ADAMTS17,ASTN2,FBXW11,ZNF34,HHIP,TPM2,WBP2,TMPRSS5,TUBB2A,ZIC2,ZNF70,GDPD5,SIGLEC10,ACTR3B,FAM198A" MicroRNA hsa-miR-519e:PITA hsa-miR-519e:PITA_TOP PITA 9.38E-26 5.27E-22 2.09E-25 1.93E-24 52 176 "ARHGAP20,ANK3,DDX3Y,CACNA1D,QKI,SLC35F1,CLOCK,CS,DOCK4,ALKBH8,DLG2,NR1D2,PDCD6IP,DYRK1A,EPB41,WAC,CAB39,RAB30,TOX2,KCNA1,KCNJ11,KCNK2,MAT2A,MYO5A,MYO6,RETREG2,PPP2R5E,RIPOR1,SLC6A15,CYB561D1,ATXN1,PEAR1,HSPA4L,YPEL4,SOX11,ITPRID2,SSTR1,SYT1,SYNE1,ARHGEF12,FRYL,DICER1,HHIP,RBFOX2,CADM1,LYPD6,DPYSL5,ZFAND5,SMARCAD1,RTN4,KAT6A,DPF3" MicroRNA hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 9.54E-26 5.36E-22 2.13E-25 1.96E-24 86 461 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,MBNL2,ABI2,IRAK4,ELAVL2,BSCL2,ERBB4,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,TRPS1,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-203a-3p:Functional MTI Functional MTI miRTarbase 9.89E-26 5.56E-22 2.21E-25 2.03E-24 69 308 "ARID1A,FMNL2,SLC12A5,CASK,MARCH3,ASPA,DDX3Y,ATM,BCL2L2,BCL7A,FOXK1,FOXN3,SOCS6,TJP2,HECTD1,CLOCK,UBXN2A,KIAA0408,ZEB2,FBXL5,DNAJB6,EDNRA,SEMA3D,SH3GLB1,MRO,RGS17,EN2,ANKRD13B,NCALD,VPS26C,DLC1,POLR1B,ZBED3,GABRB1,GNAS,RAPGEF1,CIT,WIF1,HTR2A,KIF2A,LIFR,LOH12CR2,SMAD9,MBNL1,NFYA,PAX6,PSAT1,PRKACB,MAPK8,MAPK9,FBXW7,PEAR1,CPEB4,CXXC4,KIF13A,SON,FAM208A,TBCEL,TCF4,SATB2,ZEB1,SLC44A1,NR2C2,TRPS1,ZNF24,DHX33,CADM2,NETO2,SPATA13" MicroRNA hsa-miR-423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-25 6.27E-22 2.49E-25 2.29E-24 73 343 "GPRIN1,PNMA8B,AK2,IGDCC4,ARHGDIA,ARRB2,ASPH,KIF1A,MTMR3,FOXK1,TRIM41,USP6,CD81,ARHGEF2,EVI5L,SRSF11,TMEM184B,SLITRK5,NOS1AP,ARHGAP32,SPATA2,COPS7A,RPS6KL1,ATN1,ABCC5,EIF1,EPB41,ANKRD13B,BRSK1,NKX6-2,SEPT9,AHDC1,GJB1,GLUL,POLL,PRRC2B,TDRKH,B4GALNT4,GRID1,RNF165,KCNK3,MDM4,MMP17,NFIX,OLR1,PDPK1,PFKFB3,ZNF655,PKM,KCTD15,EPN1,MTRF1L,SALL1,COPZ1,CLSTN1,SLC2A5,LIMS2,TEX2,NFASC,TAB2,MAPK8IP3,SEPT8,DIP2A,AJAP1,PLCB1,NSD1,KCTD2,WBP2,RPL7L1,POLR3H,CSDE1,URM1,WIPF2" MicroRNA hsa-miR-369-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-25 6.67E-22 2.65E-25 2.44E-24 50 163 "ABCF1,XKR4,ADD2,ADD3,CDC14B,STX16,NRP2,CA8,ABCG2,QKI,NIPBL,SLC25A27,BAG4,PITPNC1,TMTC1,MBNL2,ACSL4,ZBED3,TNRC6A,LUZP2,NR3C1,BACH2,MIER3,KLRC3,LSAMP,CCDC80,MYBPC1,NAP1L2,OCRL,PKM,EPDR1,MAPK7,ZFHX4,ATXN1,BTBD3,ZNF621,SYP,TACC1,CAMSAP2,TRIM2,SIK3,ZMAT3,HHIP,TRPS1,TUBB2A,UBE3A,TBC1D15,SPIRE1,PMEPA1,SLC38A1" MicroRNA hsa-miR-520e:Functional MTI Functional MTI miRTarbase 1.21E-25 6.79E-22 2.69E-25 2.48E-24 85 453 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,MAP4K4,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,EGFR,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-541:mirSVR_highEffct hsa-miR-541:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.26E-25 7.08E-22 2.81E-25 2.59E-24 88 482 "ASIC1,NDRG3,SLITRK1,ALCAM,PHF12,CNIH2,ATP2B1,ADAM23,AZGP1,SYNJ1,SCAPER,RAB29,TMEM257,LARGE1,PPT2,FHL5,COL4A5,SLC4A8,CLIP3,TRIM69,GAPVD1,ZBTB24,ELMO1,DNAJB6,FCF1,EGFR,TMEM35A,EPB41L2,SEZ6,MRPL37,RTN3,TOMM40L,PPP1R1B,SORBS1,SPECC1,RASL10A,JPH4,C1QL1,GLYR1,GNAL,LOXL3,GPR17,LINC00839,CLASRP,TOX2,MAN1B1,CFAP126,HSPA1L,INPP5B,ZNF385B,MAG,MBD1,RCOR2,NNAT,NODAL,CNOT4,NTRK2,PBX1,GNG2,CAMKV,SEPT4,BCAS3,HKR1,RGS12,ATXN2,ASIC4,KIF21A,ATF7IP,ARFGAP1,SMARCE1,SNRPN,SMOC1,ST5,PHLDB1,GANAB,SEPT3,KLHL7,ZFR2,ARC,TCF7L2,PCDHB9,TPM2,TRH,OSBP2,BEST1,TRIM9,LRP8,NAV3" MicroRNA hsa-miR-515-3p:PITA hsa-miR-515-3p:PITA_TOP PITA 1.26E-25 7.10E-22 2.81E-25 2.59E-24 52 177 "ARHGAP20,ANK3,DDX3Y,CACNA1D,QKI,SLC35F1,CLOCK,CS,DOCK4,ALKBH8,DLG2,NR1D2,PDCD6IP,DYRK1A,EPB41,WAC,CAB39,RAB30,TOX2,KCNA1,KCNJ11,KCNK2,MAT2A,MYO5A,MYO6,RETREG2,PPP2R5E,RIPOR1,SLC6A15,CYB561D1,ATXN1,PEAR1,HSPA4L,YPEL4,SOX11,ITPRID2,SSTR1,SYT1,SYNE1,ARHGEF12,FRYL,DICER1,HHIP,RBFOX2,CADM1,LYPD6,DPYSL5,ZFAND5,SMARCAD1,RTN4,KAT6A,DPF3" MicroRNA hsa-miR-490-3p:PITA hsa-miR-490-3p:PITA_TOP PITA 1.31E-25 7.38E-22 2.92E-25 2.69E-24 46 137 "RALGAPA1,MAP4K3,SHTN1,TMEM263,MAP7,CERS5,ARHGAP33,FOXN3,KMT2C,MAP4K4,CNR1,AHCTF1,ERC2,DBN1,SMG7,RBM12,EVL,ERGIC3,CAB39,GFRA2,PCDH17,BACH2,C5orf24,RBPJ,SCRT2,IBA57,KCNA1,MID1,MSI1,NCAM1,NEUROD2,CNOT4,MED1,TMEM104,OXR1,GTDC1,SCN4B,DOCK10,CHD9,SLC1A3,FAM219A,SOX11,SYT1,TP53BP1,NR2C2,AMOT" MicroRNA hsa-miR-520h:Functional MTI Functional MTI miRTarbase 1.37E-25 7.68E-22 3.04E-25 2.80E-24 80 407 "XKR4,PLEKHH1,ZNF578,SMIM17,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CFL2,ABCG2,ZNF385A,ENTPD4,DCAF8,DNAL1,PLEKHM1,RABGAP1L,RAB39B,DMD,SLC12A6,DNAJB6,ST8SIA3,HIPK3,CELSR3,IRAK4,ELAVL2,PLEKHA1,RGS17,COQ7,TLR7,SCML2,GTF2IRD2,SEMA4D,MSANTD4,TRAF3IP2,SYT17,KIAA1841,SRCAP,TNRC6A,PRUNE2,MFSD2A,FICD,HAS2,HMGB1,NKD1,METTL21A,KCND3,GPR155,MAPT,P2RX7,KCNK10,PIK3C2A,ZNF426,PPP2R5E,PROX1,OCIAD1,PEX2,KLHL11,C12orf49,FOXRED2,DRAXIN,HSPA4L,ATF7IP,SP2,CEP68,STAC2,WWC1,SATB2,GPRIN3,ZMAT3,CBX5,TMPO,PARD3,VLDLR,NSD2,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-6884-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-25 8.10E-22 3.21E-25 2.95E-24 92 522 "ABCF1,AS3MT,NDRG3,PNMA8B,SLC24A4,TXNDC16,CEP126,KIF6,LRFN1,AQP6,ARHGDIA,ATM,ZNF583,SYNJ2,BTRC,CCNT1,SLC16A4,NRXN3,CLU,SUMF2,MFSD4A,SLC35F1,CRY2,IPCEF1,RIMS4,UBXN2A,KIAA0408,MYADM,KIAA0513,TMEM170A,ELMSAN1,DNAH9,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,ZNF589,ATP13A4,CRCP,GPR75,GLUL,ZNF638,GPT2,KIF3A,BVES,ATOH8,AGBL5,IGF1,KLHL23,SMAD9,MATN3,MDM4,PPM1L,SLC11A2,PSD,APTX,MTMR10,TMEM145,QDPR,PLEKHB2,KLHDC8A,GSTCD,PTGR2,AMBRA1,SLC2A5,SEPHS1,SLIT1,WDTC1,CDK19,MCF2L2,RAP1GAP2,DDN,LHPP,FAM208A,TPCN2,SLC19A3,AKNA,PCDHA6,ARL10,TPM3,SSBP2,WNK1,EVI5,URM1,SNX27,MPPE1" MicroRNA hsa-miR-455-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-25 8.76E-22 3.46E-25 3.19E-24 117 784 "ABCF1,NDRG3,PLEKHG5,SLC24A4,AP1B1,HECW2,HACE1,ZNF578,USP37,APP,AQP6,CDC14B,ASPA,STX16,ZNF583,DOCK11,BACH1,BCL7A,FOXK1,PTBP2,CBS,CBFA2T2,MYOM2,CDR1,CCPG1,JAM2,NRXN3,PLAA,TPP1,ACBD5,PLCXD3,MYADM,GAPVD1,RIMS3,TMEM170A,DNAL1,HP1BP3,GUCD1,MTX3,DNAH9,MRO,RASA4,EIF4G1,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,BAIAP2,TRMO,NPTN,KBTBD12,MTHFD2,DISC1,KIAA1841,CRCP,GLUL,GNG4,LILRA2,RFFL,KIF3A,MIER3,SCRG1,IGF1,IBA57,MOBP,MPP2,CCDC80,MXI1,NASP,NUCB1,KCNK10,PDGFRA,PFKP,CCSER2,TNPO2,FAT3,TATDN3,NDUFS7,NCR3LG1,MTMR10,CEP97,ZNF793,RBBP8,ALG9,PTGR2,NCBP3,ATXN1,FNIP1,SLC30A10,SHC4,MAGI3,CLSTN1,SLC1A2,ATF7IP,SCN3B,SON,KIF21B,FNBP1,LHPP,MGRN1,ZEB1,USP22,BHLHB9,TPM3,WBP2,PPIL6,SSBP2,RFTN2,USP1,LAT2,PLPP4,EVI5,JPH3" MicroRNA hsa-miR-486-3p:PITA hsa-miR-486-3p:PITA_TOP PITA 1.62E-25 9.12E-22 3.61E-25 3.32E-24 50 164 "OGT,CNIH2,FAM131A,MARK4,CHRD,BSN,KMT2C,NRXN2,CNTFR,CLIP3,RIMS4,SRGAP3,G3BP2,CPEB2,EIF4G1,ZIC4,TESK2,BAIAP2,AGAP3,FLNC,SYT3,AHDC1,TTBK1,LOXL3,ATF7,GRIN1,CIT,KLF12,ITPKB,CAMK2N2,MAPT,NEFH,NFIX,EPB41L4B,SH3KBP1,PKIA,RNF220,YPEL4,SOX10,GSE1,PLCB1,SYP,TCF7,TCF12,RELL2,FNDC5,SSBP2,RPRM,TMEM178A,SLC17A7" MicroRNA hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 1.77E-25 9.96E-22 3.94E-25 3.63E-24 86 465 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,TAC1,WWC1,SATB2,PSD3,GPRIN3,LEFTY2,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,SLAIN1,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-188-5p:PITA hsa-miR-188-5p:PITA_TOP PITA 2.08E-25 1.17E-21 4.62E-25 4.26E-24 54 193 "ASIC1,GPR158,ZNF578,OGT,TMEM263,BCL7A,CACNA1A,KMT2C,NIPBL,PCYT1B,ACBD5,TCAF1,HDAC4,MTX3,SLC12A6,NBEA,PCDH11X,TPPP,KAT7,ADAMTS6,FRMD5,KLF12,NKD1,INSM1,MBNL1,MEF2C,MGAT3,MXI1,ZC3H12B,PCDH9,PDE3B,PTX3,USP47,ZFHX4,FBXW7,ATXN1,FNIP1,KIF16B,FBXO11,TRIM67,SLC12A2,TET1,EPC1,MYT1L,LMO3,LARP4,LRRC4,ERBIN,ANKRD12,CAMTA1,ZFP91,RBFOX2,NSD2,SOCS4" MicroRNA hsa-miR-548f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-25 1.18E-21 4.65E-25 4.28E-24 63 262 "ADARB2,SPOP,STX16,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,UBXN2A,KIAA0513,DBN1,G3BP2,TMTC1,RCAN2,TAOK3,MED12L,CAMSAP1,ZMYND11,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,LAMP2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,MAPK8,CNNM2,NWD1,RAVER2,SGK1,PEX26,LRRC55,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-483-3p:PITA hsa-miR-483-3p:PITA_TOP PITA 2.26E-25 1.27E-21 5.02E-25 4.62E-24 41 108 "ADCY6,OGT,APBA2,BCL7A,CAMK2G,FMNL3,QKI,MFAP3L,FAM13A,PAN3,DLC1,FGF12,TACC2,GHR,SPIN1,RAPGEF1,BACH2,IGF1,CAMK2N2,MAP2,NTRK3,ODF2,PCMT1,TNPO2,MED1,RASGEF1B,SATB1,FNIP1,CPEB3,AMBRA1,SLC1A3,SLC6A8,YPEL4,RCOR3,FAM126B,EXOC7,WWC1,R3HDM1,UBTF,XPO1,CSDE1" MicroRNA hsa-miR-4698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.57E-25 1.44E-21 5.69E-25 5.24E-24 57 216 "XKR4,ALAD,SPOP,APP,KIAA1614,ZMYM4,EVI5L,DLGAP3,PLAA,BTF3L4,TOGARAM2,TENM4,CENPL,SPATA2,G3BP2,GNE,EDIL3,FEM1B,EIF5,TENM1,ELAVL2,DCTN4,MRPL37,MED12L,CELF1,ZMYND11,RAPGEF6,FUT10,NUDT21,HAS2,ZNF181,KPNA5,CHST6,OLR1,GPR137C,PAK3,PDE1A,CCSER2,ZNF426,RFX3,KLHL11,SETD5,FBXW7,BDP1,SOX11,PEG10,ZC3H13,TAB2,NECAB1,SYPL1,TCF7L2,SLC19A3,ZMAT3,TLR4,TBC1D15,ZNF708,ZXDA" MicroRNA hsa-miR-548x-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-25 1.47E-21 5.80E-25 5.34E-24 63 263 "ADARB2,SPOP,STX16,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,UBXN2A,KIAA0513,DBN1,G3BP2,TMTC1,RCAN2,TAOK3,MED12L,CAMSAP1,ZMYND11,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,LAMP2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,MAPK8,CNNM2,NWD1,RAVER2,SGK1,PEX26,LRRC55,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-548aj-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-25 1.47E-21 5.80E-25 5.34E-24 63 263 "ADARB2,SPOP,STX16,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,UBXN2A,KIAA0513,DBN1,G3BP2,TMTC1,RCAN2,TAOK3,MED12L,CAMSAP1,ZMYND11,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,LAMP2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,MAPK8,CNNM2,NWD1,RAVER2,SGK1,PEX26,LRRC55,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-548g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-25 1.47E-21 5.80E-25 5.34E-24 63 263 "ADARB2,SPOP,STX16,NIPA1,CALM1,PTBP2,EVI5L,CFL2,QKI,BTF3L4,ACBD5,UBXN2A,KIAA0513,DBN1,G3BP2,TMTC1,RCAN2,TAOK3,MED12L,CAMSAP1,ZMYND11,MTHFD2,MALT1,RAB30,GRB10,ELOVL5,AGFG1,ZNF678,CLVS2,LAMP2,ARHGAP12,MBNL1,CHIC1,ZNF680,CCDC80,NFYA,CNOT4,GPR137C,PPP2R5E,PRKACB,MAPK8,CNNM2,NWD1,RAVER2,SGK1,PEX26,LRRC55,SLC6A8,KIF13A,CDK19,SPART,POGZ,DIP2A,ARC,DICER1,TUBB2A,ZNF154,ZXDA,MFF,STOX2,ITM2C,WNK3,FXR1" MicroRNA hsa-miR-1202:PITA hsa-miR-1202:PITA_TOP PITA 2.86E-25 1.60E-21 6.32E-25 5.82E-24 49 159 "SLITRK1,SNX30,PDZD4,MAP4K3,DDX3Y,BCL7A,JAZF1,FMNL3,TAOK2,NDST3,BTF3L4,ARHGEF4,PPP6R2,TOX,RIMS3,POM121,DMTF1,DNAJB6,PHC2,ETV1,TAOK3,PCDH17,RND1,GLS,DCLK2,EML4,MYO5A,PDE1B,CDK14,RETREG1,PRKCB,PTCH1,ZFHX4,NTNG1,FNDC3A,SLC1A2,BTBD3,CPEB4,RGL1,GSE1,PUM2,RELL2,RIMBP2,CSMD1,TPM3,MEAF6,TMEM237,LAMP5,HNRNPA3" MicroRNA hsa-miR-628-5p:PITA hsa-miR-628-5p:PITA_TOP PITA 2.86E-25 1.60E-21 6.32E-25 5.82E-24 49 159 "ARID1A,SLITRK1,RTL9,ANK3,CASK,ATP2B1,BLM,CACNB2,PTBP2,CAMK2G,CDH10,QKI,RIMS2,PLEKHM1,G3BP2,GOLT1B,NBEA,OGA,PHYHIPL,GABRA4,GPD1,GRIN1,HMGCR,KTN1,MAT2A,MEF2C,MEIS1,MEIS2,MYO5A,MYO6,NFIA,PRTG,PDPK1,NALCN,PLP1,MED1,PPP5C,SCN2A,SCN3A,RCOR3,SP2,NKAIN2,TCF4,TRIM2,AP4E1,SMARCAD1,TMEM178A,SNX27,HNRNPA3" MicroRNA hsa-miR-1226:PITA hsa-miR-1226:PITA_TOP PITA 3.04E-25 1.71E-21 6.73E-25 6.20E-24 52 180 "KCNH8,OGT,BCL7A,HAP1,CAMK2G,CDC42,MAP4K4,CREB5,AATK,LRIG1,OSBPL3,ALKBH8,DLG2,DPH1,ABI1,GPR61,ELAVL3,ELN,DCTN4,ERBB4,AFF2,SYT3,LOXL3,MCHR1,ACOT7,SLC6A17,KCNMA1,MAT2A,MBD1,NPTX1,FAT3,MED1,TMEM255A,CYB561D1,ROBO1,FBXW7,SOX6,CASC3,FAM102A,FBXO11,SMTN,CPEB4,RIMS1,PALLD,SOX5,SOX11,LMO3,ERBIN,SEPT3,PRRC2C,THRA,SYNC" MicroRNA hsa-miR-518e:mirSVR_lowEffct hsa-miR-518e:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.29E-25 1.85E-21 7.27E-25 6.69E-24 79 403 "DGCR6,NCKAP5,NDRG3,PSMG3-AS1,ADCY5,BRAP,RNF150,ZNF578,LRRC7,PPFIA1,PHYHD1,PPFIA3,LINC00173,BACH1,BTRC,CACNB2,THSD7A,TRIM41,CASC2,NRXN1,MAP4K4,MYRIP,ZNF385A,SLC32A1,ABCG1,SOCS5,EARS2,SPOCK2,CTIF,SPATA2,USP3,DNM2,CELSR3,EPHB1,SLC9B2,FLNC,TUBA8,GGTA1P,ZNF276,TNRC6A,ZNF638,PCLO,RAPGEF4,MAEL,ATXN2L,TLX1,AGFG1,MOBP,RTL5,ZC3H12B,NEFH,NME4,PFKFB4,CCSER2,PLIN1,ING3,POU6F1,SIDT1,MTMR10,SH3TC2,RBBP8,CCDC25,FOXRED2,ZNF365,SMTN,CPEB4,RBM34,MGRN1,AKNA,TTTY15,TUBB1,P2RY12,LGI4,PARP11,PDSS2,DOCK8,KAT6A,TTC7A,FRMD6" MicroRNA hsa-let-7d-5p:Functional MTI Functional MTI miRTarbase 3.40E-25 1.91E-21 7.51E-25 6.92E-24 78 394 "FZD9,MTUS1,ZNF578,FAM135A,APP,AQP6,IGDCC4,NCOA1,BACH1,FMNL3,CRY2,TOMM20,DNAL1,SPATA2,ZEB2,ZBTB24,MTX3,DNAH9,ARRDC4,GOLT1B,E2F6,EDN1,ANKRD46,RBM12,EIF4G2,PLEKHO1,KATNAL1,TUBB4A,DLC1,TOMM40L,TRMO,PDLIM5,CELF1,SALL3,DISC1,GATM,TNRC6A,POLL,FUT10,RABL2A,IL6R,KPNA5,PAXBP1,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,RFX5,ATXN2,KIF27,FNDC3A,ERC1,PEG10,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,DICER1,TGFBR3,CBX5,RBFOX2,TPD52L2,TST,TUBB2A,SLC35A4,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-299-3p:PITA hsa-miR-299-3p:PITA_TOP PITA 3.45E-25 1.94E-21 7.62E-25 7.02E-24 41 109 "SLC25A25,RTL9,OSBPL8,SEMA6A,ANK1,MADD,ZBTB10,CACNB2,RUNX1T1,CDC42,DLGAP3,TMEM155,SLC35F1,CLIP3,DOCK4,IP6K1,DLG2,APH1A,TMEM35A,GRIN2D,KAT7,HMGB1,IGF1,ITGAV,KCNMA1,GIT1,MSI1,OPCML,GNG2,PRRX1,SGSM1,CSRNP3,CHD9,FAM126B,MYT1L,SOX5,SP4,MTCL1,TCF4,UBE2H,RNF146" MicroRNA hsa-miR-629:PITA hsa-miR-629:PITA_TOP PITA 3.60E-25 2.02E-21 7.96E-25 7.33E-24 48 153 "ERMN,FZD9,SNX30,KLHL13,OSBPL8,SEMA6A,CNTNAP1,ARHGAP5,CADPS,BTRC,LETMD1,CS,AIF1L,KIAA0753,CPEB2,EIF1,AMOTL2,UBE2E3,AGAP3,GABRB3,GAD2,C15orf41,PCDH17,CSDC2,RNPS1,SPIN1,PCLO,GRIN2D,KAT7,SMAP1,IGF1,USP54,NCAM1,MED1,MAPK10,ATXN1,FAM102A,BTBD3,WDR47,SOX5,SOX11,HECW1,CLSTN2,ELOVL4,TCF4,WBP2,LAMP5,FZD3" MicroRNA hsa-miR-3667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.63E-25 2.04E-21 8.02E-25 7.39E-24 58 225 "XKR4,ASGR1,DDR1,LURAP1,CDH8,LRRFIP1,B4GALT6,NRXN3,DNAJB5,CREB5,TENM4,PDE4DIP,PITPNM3,PLCXD3,RASSF2,RIMS3,IP6K1,USP3,OPTN,PLEKHO1,ERBB2,ANKMY1,REEP2,HHIPL1,SRRM4,LYVE1,TXNL4A,TCERG1,FAM107A,PADI2,ELOVL5,HMGCR,KCNJ4,KIF5A,MDFI,MEIS1,MN1,C10orf105,MYO5A,PKD1,POLG,PRKCB,BCAS3,MSANTD2,GTDC1,KIRREL1,ASIC4,ZFP30,SLIT1,PALLD,NSFL1C,ACSBG1,TMEM151B,NSD1,AHCYL2,DAAM2,TNR,WIPF2" MicroRNA hsa-miR-1233:mirSVR_highEffct hsa-miR-1233:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.79E-25 2.13E-21 8.36E-25 7.70E-24 71 332 "FMNL2,ADD2,AXIN2,PLEKHH1,ADRB2,CC2D2A,NCOA1,SLC4A4,SYNJ2,SPAG9,LDB2,FEZ1,SPOCK2,MYEF2,DLG2,DTNA,ECM2,E2F5,PHF20L1,LRRC17,KCNMB2,DUSP27,PRMT5,FGF13,POLK,CAP2,AKAP3,HRASLS5,PCLO,PRDM5,PSIP1,ZNF491,HSD17B1,STXBP5,SYTL4,MYO9A,SFR1,NEK1,NTRK2,PCSK5,TMEM38A,GDPD2,RGS12,RNASE1,SUGCT,GSTCD,ROBO1,ATAT1,RTKN,CNKSR2,CTXN2,SLC14A1,ELMO2,SOX5,POGZ,GANAB,VPS13A,COBL,MTCL1,KLHL4,VWA3A,CRB1,MTMR14,TPM3,SYNPO2,RPL7L1,LYPD6,MEIS3,HPS4,NAV2,LAS1L" MicroRNA hsa-miR-520g-3p:Functional MTI Functional MTI miRTarbase 3.89E-25 2.18E-21 8.57E-25 7.90E-24 79 404 "XKR4,PLEKHH1,ZNF578,SMIM17,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CFL2,ZNF385A,ENTPD4,DCAF8,DNAL1,PLEKHM1,RABGAP1L,RAB39B,DMD,SLC12A6,DNAJB6,ST8SIA3,HIPK3,CELSR3,IRAK4,ELAVL2,PLEKHA1,RGS17,COQ7,TLR7,SCML2,GTF2IRD2,SEMA4D,MSANTD4,TRAF3IP2,SYT17,KIAA1841,SRCAP,TNRC6A,PRUNE2,MFSD2A,FICD,HAS2,HMGB1,NKD1,METTL21A,KCND3,GPR155,MAPT,P2RX7,KCNK10,PIK3C2A,ZNF426,PPP2R5E,PROX1,OCIAD1,PEX2,KLHL11,C12orf49,FOXRED2,DRAXIN,HSPA4L,ATF7IP,SP2,CEP68,STAC2,WWC1,SATB2,GPRIN3,ZMAT3,CBX5,TMPO,PARD3,VLDLR,NSD2,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-660:PITA hsa-miR-660:PITA_TOP PITA 4.09E-25 2.30E-21 9.03E-25 8.31E-24 50 167 "ABAT,UNC79,PKP4,APP,STX16,LDLRAD4,MAGI1,ARHGEF6,TOX,DGKB,G3BP2,DYRK1A,RBM12,ERBB4,NBEA,PPARGC1A,CIT,KIF3A,IL1RAPL1,BVES,MIER3,INSYN2,LIFR,MEF2C,MEIS1,NAP1L1,NPTX1,NRCAM,OPCML,PCDH9,PCSK2,SH3TC2,RAP1GDS1,RFX3,ZNF532,SEMA6D,SCN2A,SCN3A,SCN4B,SFPQ,TBX15,TCF4,SATB2,ARHGEF12,CADM1,FAM155A,VAV2,WNK3,CBLN2,SENP7" MicroRNA hsa-miR-562:PITA hsa-miR-562:PITA_TOP PITA 4.09E-25 2.30E-21 9.03E-25 8.31E-24 50 167 "ZNF608,PCDH19,ARHGAP20,AMPD3,SEMA7A,ZBTB10,NCOA1,ATP2A2,NOL4,ZMYM4,NRXN1,DNAJB5,HECTD1,AKAP5,FRMPD4,MATR3,ELMSAN1,MEX3B,SYNCRIP,GAB1,GHR,PPARGC1A,KCNMB4,PSIP1,IGF1,KIF5C,CHIC1,PCSK2,PPP2R5C,RELN,PTPRG,SH3TC2,RDX,FIGN,TMEM100,PPM1E,SLC12A2,MYO16,SOX3,SOX5,ZBTB43,CLASP2,NKAIN2,NECAB1,PRRC2C,TRIM2,TPM1,UBE3A,SLC17A6,SMIM8" MicroRNA hsa-miR-450b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.29E-25 2.41E-21 9.44E-25 8.70E-24 55 203 "ARID1A,KCTD16,SEMA6A,GAS7,MIER1,SLC7A14,BACH1,BCL7A,BID,CALM1,SCARB1,COL9A2,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,SPATA2,TIAM2,GUCD1,ST8SIA3,EDN1,STARD3NL,EPHB1,SLC43A2,WAC,ACSL4,SCML2,FER,HBS1L,SALL3,PRRC2B,HMGB1,RBPJ,LIMS1,SESN3,OCRL,P2RY1,PLIN1,STRN3,MAPK8,ACSS3,NWD1,ACER3,KCNIP3,SATB1,SLC30A10,PEX26,LRRC55,SOX2,UNC5D,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-654-5p:mirSVR_highEffct hsa-miR-654-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.43E-25 2.49E-21 9.76E-25 8.99E-24 86 471 "ASIC1,NDRG3,SLITRK1,PHF12,CNIH2,ATP2B1,ADAM23,AZGP1,SYNJ1,SCAPER,RAB29,TMEM257,LARGE1,SYNPR,PPT2,FHL5,COL4A5,SLC4A7,SLC4A8,CLIP3,TRIM69,GAPVD1,ZBTB24,ELMO1,ECM2,DNAJB6,FCF1,EFNA3,EGFR,SEZ6,MRPL37,RTN3,TOMM40L,PPP1R1B,SPECC1,RASL10A,JPH4,C1QL1,GLYR1,LOXL3,GPR17,LINC00839,CLASRP,TOX2,MAN1B1,CFAP126,IDH3B,INPP5B,ZNF385B,MAG,MBD1,RCOR2,NNAT,NODAL,CNOT4,NTRK2,PBX1,PFKFB2,CAMKV,BCAS3,HKR1,RGS12,RPL15,DGLUCY,ATXN2,SCN2A,ASIC4,KIF21A,ATF7IP,ARFGAP1,SMARCE1,SNRPN,SMOC1,ST5,PHLDB1,SEPT3,KLHL7,ARC,TCF7L2,PCDHB9,TPM2,OSBP2,BEST1,TRIM9,SLC30A3,LRP8" MicroRNA "GGGCATT,MIR-365:MSigDB" "GGGCATT,MIR-365:MSigDB" MSigDB 4.81E-25 2.70E-21 1.06E-24 9.76E-24 40 104 "ADD3,PHF12,API5,ARRB2,SYNJ1,KALRN,CREB5,SOCS5,HDAC9,HDAC4,TIAM2,SRGAP3,G3BP2,RBM12,ETV1,EFEMP1,RAPGEF4,ADAMTS6,HMGCR,KCNH2,LAMP2,ARHGAP12,PAX6,TRHDE,ING3,PPP5C,GRAMD1C,SNRK,REV3L,SGK1,WDR37,SLC8A2,USP33,ANKRD28,SATB2,HHIP,TLL2,SGK3,RICTOR,FMN2" MicroRNA hsa-miR-6832-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.87E-25 2.74E-21 1.07E-24 9.87E-24 69 316 "ADCY5,ADCYAP1R1,ADORA3,MTA3,AK2,USP37,SEMA4G,ARSE,BID,MYRF,SYT6,BRSK2,CBS,CDH8,ZNF445,SRSF11,SLC22A6,SEC31B,CREB5,IPCEF1,CHD5,PLCXD3,ELMSAN1,CHRDL1,PHF20L1,STARD3NL,SLC43A2,FOXO3,ANKFY1,GALC,WASF3,FAXC,SRCAP,SULT1C4,KCNMB4,TPPP,PTPRT,GPR45,DDX19B,BACH2,MIER3,KCNB1,LSAMP,MBNL1,XRRA1,SAMD5,NPTX1,OLA1,PPP3CC,ZSCAN2,MARCH1,CEP97,GTDC1,ELP2,UEVLD,TMEM156,ATXN1,ATXN7,GALNT10,MYO18A,LRRC55,ZCCHC24,CLUAP1,SMOC1,LRRC4,TCF7L2,SLC38A1,SIGLEC10,WNK3" MicroRNA hsa-miR-566:mirSVR_lowEffct hsa-miR-566:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.87E-25 2.74E-21 1.07E-24 9.87E-24 69 316 "ABAT,EMILIN3,PLEKHG5,ADCY6,LCNL1,DISP3,MARCH4,ANK3,CDC14B,MARCH3,CHID1,CADM3,CFAP410,PRC1,CBARP,CHGA,ARHGAP22,DLGAP3,WHRN,CABP1,GIT2,DGCR5,DNAH9,DTNB,EDN1,EEF1A2,TMEM132E,SORBS3,FGF1,FHL1,SDCBP2,ILDR2,ERAP1,SPIN1,STARD3,RFFL,SPACA9,GRIN1,CACFD1,CELF5,KCNJ11,MAG,MBNL1,TM6SF1,MPP2,SFR1,CDK18,PDE4D,NECAB2,RBBP8,ARHGEF10L,DCUN1D2,CCDC25,HSD11B1L,ST6GALNAC6,SUPT20H,SMARCE1,ANKRD36,KIF13A,KDM4C,TAB2,KANK1,SEPT3,CNTN2,LEFTY2,TPM4,LINC02210,SIGLEC10,FAM47E" MicroRNA hsa-miR-183-5p:Functional MTI Functional MTI miRTarbase 4.93E-25 2.77E-21 1.08E-24 9.98E-24 73 351 "ABCF1,SLC25A25,SLC24A4,MTUS1,MRTFA,ZFAT,API5,ARHGDIA,STK33,TMEM108,BTRC,SOCS6,NIPBL,BAG4,AKAP12,CS,PITPNM3,PHF14,ARHGAP32,DBT,PLEKHM1,GUCD1,RACK1,SUCO,ARFGAP2,CELF1,DKK3,USP19,GPR75,GLUL,FUT10,NR3C1,HSP90AA1,C5orf24,ITPKB,KLHL23,KIF2A,KIF5C,MDM4,HNRNPM,NEUROD2,PFKFB3,KCTD15,RC3H2,PTPA,PSMD13,PIGG,ZIK1,RAB5B,PLEKHB2,RALGDS,REV3L,ZFHX4,PPP4R3A,ANKRD36,RBM34,MYCBP2,ERC1,ZNF621,SSTR2,ERBIN,MPRIP,ZC3H4,SIN3B,ZEB1,USP22,TRO,TUBB1,RPL7L1,MEAF6,ZNF24,WNK1,RTN4" MicroRNA hsa-miR-326:PITA hsa-miR-326:PITA_TOP PITA 5.12E-25 2.88E-21 1.13E-24 1.04E-23 53 189 "RALGAPA1,SDE2,CASKIN1,ATP2B2,BCL2L2,DLGAP2,WHRN,CRY2,CSNK1G3,RIMS4,KIAA0513,FAM107B,DPYSL2,EBF1,EGR3,FGF11,ARFGAP2,GAB1,BRPF3,GGT7,GNAO1,GPD2,ADAMTS6,CELF3,MIER3,ZIC5,LRRTM1,SYT9,PABPC1L2A,NFIX,PALM,KCTD15,PPP3CB,PRKAB2,PKIA,UHRF1BP1,FAM120C,BSDC1,KCNIP2,ATXN1,SEC14L1,ITSN1,MAGI3,FNDC3A,BTBD3,EPN2,SLC8A2,SNCB,ERBIN,TCF4,AHCYL2,VLDLR,PPP1R3F" MicroRNA hsa-miR-330-5p:PITA hsa-miR-330-5p:PITA_TOP PITA 5.12E-25 2.88E-21 1.13E-24 1.04E-23 53 189 "RALGAPA1,SDE2,CASKIN1,ATP2B2,BCL2L2,DLGAP2,WHRN,CRY2,CSNK1G3,RIMS4,KIAA0513,FAM107B,DPYSL2,EBF1,EGR3,FGF11,ARFGAP2,GAB1,BRPF3,GGT7,GNAO1,GPD2,ADAMTS6,CELF3,MIER3,ZIC5,LRRTM1,SYT9,PABPC1L2A,NFIX,PALM,KCTD15,PPP3CB,PRKAB2,PKIA,UHRF1BP1,FAM120C,BSDC1,KCNIP2,ATXN1,SEC14L1,ITSN1,MAGI3,FNDC3A,BTBD3,EPN2,SLC8A2,SNCB,ERBIN,TCF4,AHCYL2,VLDLR,PPP1R3F" MicroRNA hsa-miR-542-3p:TargetScan hsa-miR-542-3p TargetScan 5.20E-25 2.92E-21 1.14E-24 1.05E-23 62 258 "C3orf14,GPRIN1,ALCAM,DPP10,APBB2,MARCH3,BMP7,MAP7,RUNX1T1,C1orf52,NRXN3,RCHY1,C2CD2,NCOR1,DBT,MAGI2,DDX46,CDON,HIPK3,CNNM1,EIF5,ELAVL2,EIF1,EPB41L1,MRVI1,F8,FGF12,MEGF11,NCKAP1,ATP8A2,PCDH17,GRM5,PTPRT,GUCY1A2,NXPH2,KLF12,KCNH1,KLHL23,LSAMP,MID1,MMP16,DBNL,SAMD14,NOVA1,PAK3,PDE4D,CDK14,NOMO2,CDIP1,ROBO1,CSRNP3,PRCD,ASRGL1,FHOD3,R3HDM2,KDM3A,COLGALT2,CUX2,PSD3,PUM2,CBX5,MFF" MicroRNA hsa-miR-887:mirSVR_lowEffct hsa-miR-887:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.23E-25 2.94E-21 1.15E-24 1.06E-23 70 325 "PWWP2A,RNF150,ALCAM,AMPD2,CASK,ASCL1,CAPRIN2,RASL11B,ATP2B2,DST,ZNF501,RGN,NRXN3,CNGA3,IGLON5,BTF3L4,CP,ARHGEF10,VCAN,SPATA2,DCTN1,MAGI2,POM121,GRIN3A,DMTF1,MAMLD1,DNAJB6,EDNRB,HIPK3,C3orf18,ETV1,ATP8A1,GORAB,KHDRBS3,SARAF,GAD2,C15orf41,TNRC6A,TDRKH,GRIA2,ADAMTS13,SERP2,BTN2A1,UBE2QL1,MBNL1,MYO9A,NNAT,CLDN11,PDE4D,FXYD1,PRIMPOL,MAGEL2,PPM1B,PIGG,PLPPR1,PTPRN2,RAP1GAP,UBR7,RGS3,SGSM1,RPS6KA2,LRRK2,FAM19A1,TNFRSF19,CLUAP1,ZEB1,OBSL1,SIRT1,ZNF346,AMACR" MicroRNA hsa-miR-4469:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-25 3.06E-21 1.19E-24 1.10E-23 68 308 "TMEM132B,SLC12A5,ARRB1,ARSE,ATP2B1,BACH1,CA8,CCNT1,CDH8,STOML1,QKI,TOGARAM2,PITPNM3,UBXN2A,PLCXD3,CYBB,FRMPD4,PHF19,TMEM170A,SPATA2,RUSC2,SMG7,TMCC2,ST8SIA3,HEYL,EMX2,SRARP,FER,TACC2,GABRG2,GJB1,GPR75,ZNF638,KIAA1958,GRID1,SHISA6,KCNQ3,LSAMP,MDFI,NODAL,KSR2,OLR1,ZDHHC22,TNPO2,PPP1R1A,MTMR10,PTPRG,GTDC1,ASIC4,SHANK2,CLUAP1,LRRC4,DIP2A,ACSBG1,ARC,TMEM178B,IQCE,TMEM151B,NSD1,ZMAT3,KCNK12,ZBTB16,AMZ1,ZNF225,SLC30A3,URM1,GAN,JPH3" MicroRNA hsa-miR-1294:PITA hsa-miR-1294:PITA_TOP PITA 5.56E-25 3.12E-21 1.22E-24 1.12E-23 51 175 "ADRB2,PITPNM2,SEMA4G,BCL2L2,REPS2,CDH10,CFL2,ARMC8,ZNF385A,RGS6,SEC24C,SPOCK3,DMD,EDN1,EGR3,STARD3NL,EIF1,TMEM121B,CNTRL,LINGO1,ADAMTS6,HAS2,DDX19B,KLF12,MAT2A,CHIC1,GIT1,MXI1,NEFM,PDE4D,PRRX1,PTPRD,FAM120C,KHDRBS2,MSANTD2,RDX,KCTD17,SCN4B,SEC14L1,ARX,AMBRA1,ZCCHC24,SULF2,ANKRD28,SYT4,SATB2,TRIM2,RBFOX2,TBC1D15,SF1,VANGL2" MicroRNA hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 5.56E-25 3.12E-21 1.22E-24 1.12E-23 51 175 "APBB2,IGDCC4,ATP2B1,BACH1,NRP2,CACNB4,CAMK2G,CAPN3,CSF1,PLXNA4,GREB1,FGF14,ATP2C1,NSG2,CHL1,GFRA1,IL1RAPL1,KLF12,NKD1,IL6ST,CLVS2,MEIS1,ADAM22,NAP1L1,NDP,HCN1,GPR137C,KCNK10,PCSK1,PDE3A,MED1,PTPRG,GTDC1,KLHL11,RAVER2,CPEB3,CHD9,EPC1,MBD5,PDZD2,BDP1,NPAS3,C11orf87,ELOVL4,KLHL7,KAZN,DDHD1,BHLHB9,KCNK12,HNRNPA3,GAN" MicroRNA hsa-miR-548bb-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.56E-25 3.69E-21 1.44E-24 1.32E-23 66 292 "ARID1A,TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,CDK5R1,MTMR3,FMNL3,CDC27,NRXN1,ATRNL1,FAM169A,PHF19,TOMM20,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,MDM4,THYN1,MYBPC1,MYO6,KCNK10,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,ARID4A,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,LRRC55,ATF7IP,SNCB,FAM126B,KIF1B,FAM208A,ALG1,CLASP1,HHIP,ARL10,TJP1,TRPC3,SF1,MKRN3,GAL3ST3,NAV2" MicroRNA hsa-miR-548z:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.56E-25 3.69E-21 1.44E-24 1.32E-23 66 292 "ARID1A,TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,CDK5R1,MTMR3,FMNL3,CDC27,NRXN1,ATRNL1,FAM169A,PHF19,TOMM20,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,MDM4,THYN1,MYBPC1,MYO6,KCNK10,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,ARID4A,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,LRRC55,ATF7IP,SNCB,FAM126B,KIF1B,FAM208A,ALG1,CLASP1,HHIP,ARL10,TJP1,TRPC3,SF1,MKRN3,GAL3ST3,NAV2" MicroRNA hsa-miR-548h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.56E-25 3.69E-21 1.44E-24 1.32E-23 66 292 "ARID1A,TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,CDK5R1,MTMR3,FMNL3,CDC27,NRXN1,ATRNL1,FAM169A,PHF19,TOMM20,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,MDM4,THYN1,MYBPC1,MYO6,KCNK10,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,ARID4A,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,LRRC55,ATF7IP,SNCB,FAM126B,KIF1B,FAM208A,ALG1,CLASP1,HHIP,ARL10,TJP1,TRPC3,SF1,MKRN3,GAL3ST3,NAV2" MicroRNA hsa-miR-454*:mirSVR_highEffct hsa-miR-454*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.63E-25 3.73E-21 1.45E-24 1.34E-23 68 309 "CSMD2,GRAMD1B,RTL9,TAOK1,FGD2,CACHD1,NUMB,ATP2B1,DPY19L3,CACNB2,LURAP1,CABP7,VSTM2A,SRSF11,MAP4K4,MYRIP,GREB1,NRSN1,DOCK4,GPRASP1,RIPOR2,HDAC4,DDX46,RHOBTB1,CHRDL1,ARRDC4,EDN1,EML1,EPB41L2,RAB9B,ATP2C1,FAM120B,GDF9,KIRREL3,CBX1,DIDO1,PLCD4,HSF2,NME9,POC1B,MSR1,MXI1,PABPC1L2A,NF1,HCN1,GPR137C,RETREG1,PPM1B,STK32A,C1orf109,PEX5,TMEM255A,RAVER2,ZNF331,CXXC4,TMCC1,SP4,SPTAN1,TAB2,ATP10B,FAM168A,SYNE2,PUM2,GPRIN3,TMPO,PIK3R5,TPD52L2,ATP6V0E2" MicroRNA hsa-miR-297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.76E-25 3.80E-21 1.48E-24 1.36E-23 53 190 "TMEM132B,HACE1,TAOK1,APP,CFL2,IGLON5,MYADM,DCAF8,SV2B,DMD,MBNL2,ABI2,CERCAM,EPHA5,KATNAL1,UBE2E3,GABRG1,GATM,SESN1,MMADHC,CBX1,BVES,ZDHHC15,IGF1,DOCK7,KCNJ3,KCNQ3,SYT9,MKLN1,MYO5A,NELL2,NEUROD2,OPCML,PLP1,SDK2,SPATA6,PROX1,RIC8B,PGBD4,SATB1,CSRNP3,PEX26,SMTN,NECAB1,ARHGEF9,PLCB1,HHIP,CSMD1,KCNK12,ZNF711,ZNF195,ADAMTS9,SSPN" MicroRNA "AGGGCAG,MIR-18A:MSigDB" "AGGGCAG,MIR-18A:MSigDB" MSigDB 7.01E-25 3.94E-21 1.53E-24 1.41E-23 44 129 "ARID1A,OGT,SEMA4G,STOML1,QKI,PHC2,MBNL2,PAN3,DLC1,STRADA,JPH4,CPLX2,TTBK1,CRCP,ATF7,CIT,ZFYVE27,MAPT,MAT2A,ZC3H12B,PAK3,PFKFB4,CAMKV,PSD,PBRM1,SMPD3,IL17RB,URGCP,SLC8A2,MAPKBP1,MAPK8IP3,TACC1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,LRRC8A,HIRA,EIF4ENIF1,SNX27,ST8SIA2" MicroRNA hsa-miR-202-5p:TargetScan hsa-miR-202-5p TargetScan 7.25E-25 4.07E-21 1.59E-24 1.46E-23 55 205 "ACTN1,BEND6,OGT,PKP4,APP,DST,MYRF,RUNX1T1,CBFA2T2,CS,CSF1,CTNND2,KIAA0408,GIT2,JAKMIP2,PLEKHA1,PAN3,EPB41,SCARA3,AHCYL1,IL1RAPL1,KLF12,HLF,MSL1,HES5,LSAMP,GPR155,MATN2,LDLRAD3,MEIS2,DDR2,CDK14,MED1,PPP5C,PTPRG,MARCH1,KHDRBS2,RGS3,AP1AR,ATXN2,SCN2B,CPEB3,EPC1,KDM3A,FAM189A1,PSD3,CBX5,RBFOX2,PRMT8,AMOT,FRRS1L,JMJD1C,MSRB3,FXR1,GAN" MicroRNA hsa-miR-520b:Functional MTI Functional MTI miRTarbase 7.27E-25 4.08E-21 1.59E-24 1.46E-23 84 455 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,EGFR,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-548ac:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.05E-25 4.52E-21 1.76E-24 1.62E-23 66 293 "ARID1A,TMCC3,KIAA1324,TRMT9B,AMPD3,PHF12,ARNTL,CDK5R1,MTMR3,FMNL3,CDC27,NRXN1,ATRNL1,FAM169A,PHF19,TOMM20,EDIL3,HIPK3,YAF2,CELSR3,MRO,SYNCRIP,SEMA4D,UFM1,CELF1,GABRB3,GATM,FRMD5,NEGR1,RBPJ,ZNF678,MDM4,THYN1,MYBPC1,MYO6,KCNK10,PDE4D,STRN3,PSAT1,KANSL1,PKIA,PTPRB,PTPRG,ARID4A,TMLHE,EXD2,PCMTD2,SALL1,TRA2B,BTBD3,LRRC55,ATF7IP,SNCB,FAM126B,KIF1B,FAM208A,ALG1,CLASP1,HHIP,ARL10,TJP1,TRPC3,SF1,MKRN3,GAL3ST3,NAV2" MicroRNA hsa-miR-649:PITA hsa-miR-649:PITA_TOP PITA 8.21E-25 4.61E-21 1.79E-24 1.65E-23 56 213 "ALCAM,NCOA1,CAMK2G,TMEM257,KIAA1549L,CS,CHD5,RIMS2,GAPVD1,SNAP91,CHRDL1,DMTF1,PDCD6IP,YAF2,ELAVL3,DCTN4,EIF1,EMX2,EPB41L2,JKAMP,SORBS1,STAG2,SESN1,PCDH17,PPARGC1A,KIAA1958,CECR2,GRIA1,GRIK2,BACH2,MYLK2,ZIC5,MEIS2,KITLG,MID1,FAT3,RNF220,ACER3,SCN2A,SOX6,PPM1E,WDR37,PPP4R3A,CCDC88A,TET1,POGZ,LARP4,CAMSAP2,TCF4,PUM2,AHCYL2,CADM1,PCDH20,NAV3,KAT6A,CPNE4" MicroRNA hsa-miR-5193:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.71E-25 4.89E-21 1.90E-24 1.75E-23 65 285 "SLC12A5,PRX,ATP2B3,NIPA1,CACNB2,DIS3L,SLC22A6,IGLON5,RTTN,LRIG1,PDE4DIP,CTIF,DBN1,RUSC2,TMCC2,RASA4,TMEM132C,CHST15,TMEM151A,PCDH17,KIAA1958,RAPGEF1,GRID1,GRIK3,NR3C1,GRM1,GPR45,HMGB1,TLX1,SHISA6,NKD1,C2CD4C,KCNJ11,KCNN1,KIFC3,CYP27C1,VWA5A,MAT2A,AFF1,C10orf105,NKX2-2,HMGCLL1,EXOSC10,KANSL1,PIGG,PTAFR,PRRT2,KLHL11,PEX26,PKNOX2,SLIT1,SMARCE1,BDP1,TMEM178B,FAM208A,TCF7L2,CRTC1,LEFTY2,LAT2,ZBTB16,AMZ1,DPYSL5,ZNF195,FAM13C,GAN" MicroRNA hsa-miR-28-5p:PITA hsa-miR-28-5p:PITA_TOP PITA 9.42E-25 5.29E-21 2.06E-24 1.89E-23 48 156 "PDZD4,AMPH,ANK1,SEMA4G,CACNA1G,LDLRAD4,CABP7,FMNL3,DCLK1,CDH18,CNTFR,SH2B1,GDA,GAPVD1,DPP6,SH3GLB1,EFNB3,EN2,EPHB1,FOXO3,SYT3,ZNF512,CHL1,SESN1,GPM6A,GRIA4,RNF165,HNRNPK,MAT2A,NCAM1,NFE2L2,NNAT,OPHN1,HMGCLL1,TMEM260,RDX,ATXN1,SMARCC2,IGSF9B,SPTB,SYT11,SYN2,TRPS1,PRDM2,SNX27,WIPF2,KAT6A,JMJD1C" MicroRNA hsa-miR-496:PITA hsa-miR-496:PITA_TOP PITA 1.01E-24 5.67E-21 2.20E-24 2.03E-23 50 170 "MTUS1,BCAR3,NCOA1,EIF4G3,WASF1,CALB1,CD86,CDH2,ZMYM4,FOXN3,NRXN2,QKI,ARHGEF6,SRGAP3,DNM1,GPR34,GRM5,KCNA6,MBNL1,SAMD5,NEUROD1,NOVA1,HCN1,OPHN1,LRP12,GTDC1,ATXN1,SCN3A,CPEB3,NLGN1,SEPHS1,ELMO2,CPEB4,TMCC1,MYT1L,NPAS3,SS18,ELOVL4,PLCB1,ANKRD12,FBXW11,DOCK9,SLC44A1,ERCC6L2,TRPS1,TMEFF2,FLRT2,TOM1L2,PRTFDC1,FRMD6" MicroRNA hsa-miR-6875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-24 5.69E-21 2.21E-24 2.03E-23 62 261 "RALGAPA1,FMNL2,SPOP,CACHD1,TNRC6C,ARSE,CDK13,ASCL1,ATP1A2,CDH8,NUMBL,BAG4,TENM4,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,SH3GLB1,ABI2,ELAVL3,STARD3NL,COQ7,DLC1,GORAB,GABRB1,FAXC,PCDH17,GRIK3,HAS2,NCKAP1L,NEGR1,SHISA6,SYTL4,LSAMP,SRSF12,CD200,NODAL,NOVA2,FAM98B,PLCL1,PNMA3,PRKCB,SH3TC2,TMLHE,TRAPPC13,CSRNP3,SMOC1,SSTR2,MAPK8IP3,MPRIP,DIP2A,ADAMTS17,TBL1X,ACSL6,ASXL3,FNDC5,RPL7L1,UGT8,JMJD1C,ZDHHC20" MicroRNA hsa-miR-631:mirSVR_highEffct hsa-miR-631:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.05E-24 5.88E-21 2.28E-24 2.10E-23 79 410 "ASIC2,ADCY6,SLC12A5,PHF12,PKP4,GPAM,MIER1,ATP2B2,SLC2A11,BACH1,RUNX1T1,MTMR7,MAGI1,CDO1,TPP1,AKAP7,COX4I1,SEC31B,HINFP,ANKRD44,SNCAIP,VCAN,ECE2,ZC3H11A,DDX46,DYRK1A,TMTC1,FAM13A,MRNIP,ANKRD13B,F3,ZNF461,EVL,C2orf88,TVP23A,GABRG1,ZNF274,INPP5K,TCERG1,GLUL,RFFL,C1orf94,HMGCL,KCNA1,KCNC2,STMN1,MAN2A2,MAT2A,NELL1,EPDR1,HYDIN,PTPRE,SLC25A48,RET,SLC25A36,ACER3,DGLUCY,LINC00461,AMBRA1,EPN2,KANSL3,SLC11A1,SLC12A2,ZFP1,SORCS3,BDP1,NXT2,NEK4,ACSBG1,SYNE1,MTMR14,RASD2,SYNPO2,HEPACAM,UGT8,CELF4,STMN4,RNF103,SCG2" MicroRNA hsa-miR-491-5p:TargetScan hsa-miR-491-5p TargetScan 1.05E-24 5.91E-21 2.29E-24 2.11E-23 46 143 "CSMD2,GRAMD1B,LRFN1,KIAA1614,BCL2L2,HAP1,P2RX6,CFL2,DLGAP3,FADS2,DNAJB5,NRG2,CTIF,C2CD2L,DMPK,HIPK3,EFNA3,APH1A,ELAVL3,ELAVL4,KAT8,IL1RAPL1,KAT7,CELF3,PADI2,LRRC4B,MN1,MOG,NOVA2,PDE1B,PDGFRA,NLE1,RORB,CSRNP3,FAM126B,KDM4B,MYT1L,FNBP1,PEG10,NFASC,MAPK8IP3,ARHGAP9,DDHD1,RGMB,CLIP2,PORCN" MicroRNA hsa-miR-573:PITA hsa-miR-573:PITA_TOP PITA 1.06E-24 5.94E-21 2.30E-24 2.12E-23 56 214 "GPR158,PKP4,SPAG9,CDH2,CDH10,FOXN3,KMT2C,CLTC,QKI,DPH1,MBNL2,PAN3,ZIC4,CHL1,IL1RAPL1,GUCY1A1,DDX19B,KLF12,MIER3,SMAP1,IGF1,KCNN2,KIT,HCN1,PKN2,PROX1,PTPRD,FAM120C,PID1,TMEM255A,ALG9,ATP8B4,SEMA6D,SCN2A,SLITRK3,SEPHS1,CPEB4,FAM126B,SOX5,KIF1B,ERBIN,GSE1,NECAB1,SYT1,CAMSAP2,UNC5D,SATB2,HEY2,KAT6B,FAM155A,POLR3H,PRDM10,WNK3,HNRNPA3,JMJD1C,RNF146" MicroRNA hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-24 6.07E-21 2.36E-24 2.17E-23 83 448 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA "GAGCTGG,MIR-337:MSigDB" "GAGCTGG,MIR-337:MSigDB" MSigDB 1.19E-24 6.69E-21 2.59E-24 2.39E-23 47 150 "ABCF1,KCNH8,SLC12A5,SEMA6A,GPRASP2,DGKZ,CHRD,CAMK2G,USP6,DGKI,DNAJB5,IFFO1,SEC24C,FAM131B,B3GAT3,DSCAM,ZMYND11,USP19,GLYR1,GPD1,RNF165,PACSIN2,ATXN2L,KLF12,ACOT7,LRRC75A,KCND1,MAT2A,GIT1,OPCML,ZNF827,CAMKV,MDGA2,UBR7,ROM1,SLC1A2,IQSEC2,NFASC,POGZ,LRRC4,VAMP1,PSD3,THRA,NSD2,PARP6,PPP1R3F,SNX27" MicroRNA hsa-miR-4659b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-24 6.89E-21 2.67E-24 2.46E-23 58 230 "RALGAPA1,SPOP,TNRC6C,ARSE,CDK13,ASCL1,CALM1,CDH8,TENM4,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,SH3GLB1,ABI2,TENM1,STARD3NL,COQ7,DLC1,GORAB,TMEM151A,GABRB1,FAXC,PCDH17,GRIK3,HAS2,NEGR1,SYTL4,LSAMP,SRSF12,CD200,SAMD5,NOVA2,NPTX2,FAM98B,PLCL1,PRKCB,SH3TC2,TMLHE,TRAPPC13,SEMA6D,CSRNP3,BDP1,SSTR2,MPRIP,DIP2A,FAM208A,TBL1X,ACSL6,ASXL3,TLR4,TNS1,FNDC5,RPL7L1,UGT8,ZDHHC20" MicroRNA hsa-miR-4659a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-24 6.89E-21 2.67E-24 2.46E-23 58 230 "RALGAPA1,SPOP,TNRC6C,ARSE,CDK13,ASCL1,CALM1,CDH8,TENM4,SUSD5,SOCS5,PLCXD3,DOCK4,MATR3,FEM1B,SH3GLB1,ABI2,TENM1,STARD3NL,COQ7,DLC1,GORAB,TMEM151A,GABRB1,FAXC,PCDH17,GRIK3,HAS2,NEGR1,SYTL4,LSAMP,SRSF12,CD200,SAMD5,NOVA2,NPTX2,FAM98B,PLCL1,PRKCB,SH3TC2,TMLHE,TRAPPC13,SEMA6D,CSRNP3,BDP1,SSTR2,MPRIP,DIP2A,FAM208A,TBL1X,ACSL6,ASXL3,TLR4,TNS1,FNDC5,RPL7L1,UGT8,ZDHHC20" MicroRNA hsa-miR-4533:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-24 6.89E-21 2.67E-24 2.46E-23 58 230 "ARID1A,HECW2,TAOK1,LTBP4,TRMT9B,CDC14B,PDXK,DPY19L3,TTLL9,BCL7A,FOXK1,RUNX1T1,CBFA2T2,ZNF385A,CRY2,DCAF4,FAM131B,DBN1,PHC2,EN2,GCK,TNRC6A,PRRC2B,GSN,TNFAIP8L3,ZFYVE27,PABPC1L2A,NOVA2,CDK14,PKM,ZNF426,PACSIN1,IQSEC3,PRRT2,SETD5,MYH14,DRAXIN,SGK1,SHMT2,AMBRA1,R3HDM2,PEX26,WDTC1,IQSEC2,CDK19,SS18,MAPK8IP3,MPRIP,TMEM9,ASXL3,TPD52L2,TPM3,WBP2,TUBB2A,WRN,ZNF708,CIAPIN1,ITM2C" MicroRNA hsa-miR-455-5p:PITA hsa-miR-455-5p:PITA_TOP PITA 1.25E-24 7.03E-21 2.72E-24 2.51E-23 45 137 "ACTN1,ADD3,UNC5A,INTS2,OSBPL1A,SEMA4G,CDK13,ATP2B3,DCAF5,CACNB4,THSD7A,SLITRK5,ERC2,PLCXD3,CTNND1,DOCK4,MFAP3L,USP3,DTNB,EDN1,PLXNC1,FGF13,CAB39,FRMD5,IBA57,ARHGAP12,NEXMIF,PDGFRA,GPR85,CDK14,NXPH1,KANSL1,EPDR1,ATG16L1,RGS4,STX1B,CPEB3,SOX11,SATB2,WDR7,DOCK9,CDH22,TJP1,TRPS1,ZIC3" MicroRNA hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 1.26E-24 7.09E-21 2.74E-24 2.53E-23 83 449 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-3680-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-24 7.44E-21 2.88E-24 2.65E-23 51 178 "ARID1A,KCTD16,SEMA6A,BACH1,BCL7A,BID,CALM1,COL9A2,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,MED24,GUCD1,ST8SIA3,EDN1,STARD3NL,SLC43A2,WAC,ACSL4,SCML2,FER,HBS1L,PRRC2B,HMGB1,RBPJ,LIMS1,CHIC1,SESN3,P2RY1,PDE3A,PLIN1,STRN3,MAPK8,ACSS3,NWD1,ACER3,KCNIP3,SATB1,SLC30A10,PEX26,LRRC55,TMCC1,SEPT8,UNC5D,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-383-5p.1:TargetScan hsa-miR-383-5p.1 TargetScan 1.36E-24 7.62E-21 2.95E-24 2.71E-23 50 171 "KCTD16,PPFIA2,APP,ATP2B3,MAP7,C1orf52,QKI,HDAC9,DNAL1,BLOC1S6,ELAVL2,CALCRL,PAN3,ERBB4,FECH,GAB1,RAPGEF6,NCKAP1,PCDH17,KIRREL3,CELF3,AGFG1,PLD5,KCNB1,KIF5C,HS6ST3,NEUROD1,NNAT,CNOT4,PAX6,FAT3,NXPH1,PTPRE,GTDC1,FIGN,GSTCD,RORB,GLDN,PPP1R9A,EPN2,CDK19,MPRIP,ROBO3,ARHGEF12,FRYL,HIF3A,ITGB3BP,RBFOX2,PPIL6,EPM2A" MicroRNA hsa-miR-329:PITA hsa-miR-329:PITA_TOP PITA 1.36E-24 7.64E-21 2.95E-24 2.72E-23 56 215 "DDX3Y,BCL7A,BTRC,PTBP2,KRIT1,SOCS6,B4GALT6,CLTB,IGDCC3,RBM39,CREB5,CRMP1,CRY2,CSNK1G3,CHD5,ERC2,DAPK1,IP6K1,ALKBH8,SRGAP3,CHRDL1,RBM12,EIF4G1,ERBB4,ADAM28,EML4,RNF165,KLF12,KCNMA1,MAP2,MGAT3,MYT1,OPCML,PDE4D,OLA1,CAMKV,ZFHX4,RPE,ATXN1,BTBD3,CPEB4,FAM219A,NPAS3,EPB41L3,SYT1,SYT4,CAMTA1,TAL1,RIMBP2,TRPC1,CADM1,CLDND1,TMEM237,NAV3,WIPF2,VANGL2" MicroRNA hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA_TOP PITA 1.36E-24 7.64E-21 2.95E-24 2.72E-23 56 215 "DDX3Y,BCL7A,BTRC,PTBP2,KRIT1,SOCS6,B4GALT6,CLTB,IGDCC3,RBM39,CREB5,CRMP1,CRY2,CSNK1G3,CHD5,ERC2,DAPK1,IP6K1,ALKBH8,SRGAP3,CHRDL1,RBM12,EIF4G1,ERBB4,ADAM28,EML4,RNF165,KLF12,KCNMA1,MAP2,MGAT3,MYT1,OPCML,PDE4D,OLA1,CAMKV,ZFHX4,RPE,ATXN1,BTBD3,CPEB4,FAM219A,NPAS3,EPB41L3,SYT1,SYT4,CAMTA1,TAL1,RIMBP2,TRPC1,CADM1,CLDND1,TMEM237,NAV3,WIPF2,VANGL2" MicroRNA hsa-miR-337-5p:mirSVR_highEffct hsa-miR-337-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-24 7.75E-21 2.99E-24 2.76E-23 54 200 "ZFAT,ARNTL,SLC25A14,ZNF501,TIGD7,CLTA,CNN3,COL11A2,CTH,HDAC9,HEPH,NR1D2,CPEB2,SUGP2,RPS6KC1,KAT8,ZMYND11,ERAP1,CBX1,LNX1,GPD2,GRIN2D,GRM5,AGBL5,SHISA6,SLC35G1,GATD1,SESN3,NAP1L1,NELL2,PRTG,PPP2R5C,PPP3CA,PIGG,PTPRO,PPP2R3C,ZYG11B,LINC00461,SGK1,SH3BGR,SYBU,NLGN1,PAAF1,SLC15A2,SLCO1A2,KIF1B,SLC44A1,TJP1,CCDC14,ZBTB38,ZNF195,WNK1,AMN1,KAT6A" MicroRNA hsa-miR-4446-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-24 8.75E-21 3.38E-24 3.11E-23 58 231 "ACTN2,ADCYAP1R1,RNF150,MTA3,SPOP,SEMA4G,BCL7A,DCAF5,CACNA1G,CACNA2D1,SYT6,DNAJB5,RGS6,CHD5,PHF19,TBC1D5,DMD,RCAN1,KLHL5,CELSR3,FAM13A,TBC1D16,AMOTL2,GABRB1,SRCAP,GLUL,KCNMB4,GPR26,TPPP,NR3C1,IL1RAPL1,NEGR1,RBPJ,CCDC80,NFIA,NOVA2,GLIPR1L2,PTPRE,MARCH1,ZYG11B,RORB,ATXN1,KIF21A,BTBD3,SEPHS1,SLC11A1,ZCCHC24,ZBTB43,NPAS3,SMOC1,ACSBG1,TNS1,TMEFF2,TOM1L2,ZNF177,SLC38A1,VANGL2,DPF3" MicroRNA "CAATGCA,MIR-33:MSigDB" "CAATGCA,MIR-33:MSigDB" MSigDB 1.69E-24 9.50E-21 3.66E-24 3.38E-23 37 90 "SLC25A25,SLC12A5,OGT,B3GALT2,CAMK2G,USP6,LGI1,CHN2,MAP4K4,SEC24C,ST18,CNNM1,EN2,OLFM1,SALL3,PPARGC1A,ICA1,KCNMA1,MEIS2,MMP16,NFIX,NPY,GPR88,PDGFRA,CDK14,SNRK,MDGA2,FBXW7,SCN8A,CASC3,SLITRK3,SHANK2,SOX11,SATB2,USP32P2,DPYSL5,PARP6" MicroRNA hsa-miR-208a:mirSVR_highEffct hsa-miR-208a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.76E-24 9.90E-21 3.82E-24 3.52E-23 51 179 "TMEM108,BLM,SYNJ1,PRC1,CDO1,QKI,MAP4K4,IQCK,SLC4A7,HS3ST5,ZNF804A,DDX46,PLPPR4,CPEB2,EDNRB,KCTD3,MED12L,FOXG1,ANKFY1,DISC1,CBX1,GNAS,GRIA2,GRIA4,RNF165,WIF1,HNMT,CELF5,MAOB,GPR88,TRHDE,PPP2R5C,PEX2,USP47,RGS7,RIC8B,PNMA8A,TCP11L1,RYR3,SCG5,CHD9,RCOR3,TTC17,ARHGEF9,SATB2,ZEB1,DOCK9,RALYL,ERCC6L2,CADM1,MICU3" MicroRNA hsa-miR-517a:mirSVR_highEffct hsa-miR-517a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.80E-24 1.01E-20 3.89E-24 3.58E-23 54 201 "FMNL2,ELFN2,SLITRK1,SNX32,ALCAM,MIER1,LURAP1,B4GALT6,ABI3BP,ZNF521,CS,GAPVD1,KIF26A,DBN1,SMG7,SACS,NR1D2,EGFR,ELAVL2,KCNMB2,DLC1,PRMT5,POLR1B,ARFIP1,AHDC1,GGT7,GHR,HPGDS,LINC01551,HPS5,MSL1,LRRTM3,JAK2,OLFM3,STMN1,ERICH3,NFIA,NUDT11,SYNDIG1,SLCO1A2,SMARCE1,MBD5,TMCC1,TAB2,TMEM150C,WWC1,DOCK9,AP4E1,SLC44A1,TJP1,TNS1,USP1,EML6,CBLN2" MicroRNA hsa-miR-219-5p:PITA hsa-miR-219-5p:PITA_TOP PITA 1.82E-24 1.02E-20 3.94E-24 3.63E-23 50 172 "KCNH8,FMNL2,PITPNM2,SEMA4G,NCOA1,NOL4,CAMK2G,AKAP6,CNRIP1,AKAP12,DNAJC6,RHOBTB1,CDON,CPEB2,GPR61,EGR3,EYA1,ILDR2,PCDH17,PPARGC1A,TTBK1,MIER3,MEF2C,OCRL,ZNF827,PDE4D,PDGFRA,PURG,PDZRN4,TRHDE,SNRK,FAM120C,RORB,RXRA,CSRNP3,SOX6,HSPA4L,CPEB3,NTNG1,SLC8A2,RIMS1,SOX5,ZCCHC24,SP4,ARHGAP26,KIF1B,SYT5,TACC1,NR2C2,UBE3A" MicroRNA hsa-miR-340-5p:Functional MTI Functional MTI miRTarbase 2.03E-24 1.14E-20 4.39E-24 4.04E-23 71 341 "OSBPL1A,WDR35,CC2D2A,USP28,TMEM263,CAPRIN2,ATP1A1,CALM1,SLC24A2,ABCG2,QKI,CRY2,RIMS4,APPL1,UBXN2A,GREB1,PUM1,NTM,MTX3,FEM1B,CERCAM,ELAVL4,C8orf37,RCAN2,TUBB3,SCML2,DLC1,KIAA1109,FOXO3,CAB39,C15orf41,LYVE1,ATXN2L,TLX1,ZIC5,SLC35G1,KCNK1,LIFR,LIMS1,HECTD2,ARHGAP12,MAT2A,KCTD6,MITF,MKLN1,IGSF11,PDE4D,PDZRN4,SNRK,PTPRD,PEX2,RAB5B,REV3L,FIGN,TMLHE,MCMBP,ACER3,CLIP1,ATXN1,SLC6A8,SON,SOX2,SYPL1,PUM2,KAT6B,TNS1,AMOT,ZXDA,SLC38A1,CSDE1,GAN" MicroRNA hsa-miR-1245:PITA hsa-miR-1245:PITA_TOP PITA 2.06E-24 1.16E-20 4.46E-24 4.10E-23 44 132 "CSMD3,LCORL,APP,INA,CLTC,OSBPL3,DUSP9,RBM12,PHF20L1,RCAN2,FECH,SUCO,AFF2,BRPF3,PCDH17,NUDT21,GRB10,LINGO1,KCNA1,KCNK2,NEXMIF,ZC3H12B,NPTX1,OCRL,TMEM260,FAM120C,TMEM255A,USP47,RDX,ATXN2,NLGN1,SLC1A2,RCOR3,TMCC1,SP4,GSE1,R3HDM1,CADM1,SYNC,EMSY,CSDE1,WIPF2,WNK3,SOCS4" MicroRNA hsa-miR-339-5p:mirSVR_highEffct hsa-miR-339-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.07E-24 1.17E-20 4.48E-24 4.13E-23 89 511 "NCKAP5,PLEKHH1,PTCHD1,OGT,PPFIA1,PPFIA3,SFMBT2,CCAR2,CHID1,ZNF599,CFLAR,IL33,LURAP1,NFS1,ARHGEF2,LARGE1,NRXN3,NRXN1,SUMF2,MFSD4A,COPS7A,MAGI2,NTM,RABGAP1L,DNAJB6,ABCC9,FAM135B,EMX2,EPHB1,RACK1,SORBS1,UFM1,CELF1,ZNF559,LYVE1,POLL,CNDP1,GPD2,TDRKH,PCLO,GRIK1,GRIK4,GRM3,FAM19A2,ZNF385B,INSYN2,NNAT,NOVA1,NUCB2,PDCD2,CDK14,FAM216A,PLXNB3,NXPH1,PPP3CB,GON4L,ELOVL2,TMEM260,RAB3IL1,CEP97,GAL3ST4,UBR7,CARF,KIRREL1,UEVLD,SUPT20H,ITSN1,SLA,URGCP,ARHGEF40,SLC11A1,SLC15A2,UNC80,SOX1,VPS13A,DDHD2,FRYL,MTMR14,DAAM2,NPL,METTL3,UBE3A,ZBTB14,PLPPR5,GDPD5,STOX2,HPS4,FAM219B,SLC4A10" MicroRNA hsa-miR-340*:mirSVR_highEffct hsa-miR-340*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.40E-24 1.35E-20 5.19E-24 4.78E-23 75 378 "PLEKHG5,ANK3,PPFIA1,APLP1,CACHD1,CAPRIN2,BACH1,GYG2,CALM1,SLC16A4,P2RX6,CD38,NOG,PPT2,IFFO1,MFSD4A,CHD1L,SLC35F1,CSF2RA,MICAL2,TMEM170A,GUCD1,FCF1,SYT15,IRAK4,STX2,ZNF549,F3,RACK1,CAP2,PDLIM5,TRIM16,GALNT15,SIGLEC8,COPS8,SPACA9,GRM1,ATXN2L,INPP5B,IPO5,MDM4,PLXNB3,RETREG2,PRKCG,ZSCAN2,RAD52,RADX,TRIM68,RFX4,SNX22,RPL15,GLDN,ACER3,MAPK12,FAM19A1,ZFP30,SH3GL3,R3HDM2,PAAF1,SLC6A1,RADIL,SLC12A2,ANKRD36,PDZRN3,RBM34,ZSWIM8,ERC1,SPTAN1,PCDHB9,DICER1-AS1,PPIL6,VIPR2,WIPF1,DNALI1,TRIM16L" MicroRNA hsa-let-7i*:mirSVR_lowEffct hsa-let-7i*:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.44E-24 1.37E-20 5.26E-24 4.85E-23 65 290 "INTS2,SUGT1P4-STRA6LP-CCDC180,ATP2A2,CDK5R1,ARHGEF7,CBLN1,CDH10,DCLK1,CCDC151,ARHGEF6,TCAF1,ARHGAP24,TOX,SPOCK2,ZEB2,SPOCK3,OLIG1,EGR3,EPB41L2,FGFR1,C2orf88,CELF1,TBR1,FAM120B,LRRC37A6P,GLI2,GRM7,ADAMTS6,ARHGAP19,TCEAL6,RBPJ,MEIS1,HNRNPM,ZC3H12B,NF1,NKX2-2,GLIPR1L2,PCSK5,PDPK1,PRRX1,ING3,PTHLH,USP47,CCDC40,BSDC1,ZYG11B,SEC61A2,MEG3,LINC00461,SLITRK3,ST3GAL3,SMTN,PKNOX2,SEPHS1,RAB3GAP1,MBD5,UNC80,ATP10B,ZC4H2,HIF3A,CRB1,TTC3,FAM155A,ZIC1,DPYSL5" MicroRNA hsa-miR-632:PITA hsa-miR-632:PITA_TOP PITA 2.48E-24 1.40E-20 5.36E-24 4.94E-23 45 139 "PTCHD1,FAM131A,AQP4,CADM3,KMT2C,KIAA1549L,TPP1,QKI,MAP4K4,RIMS2,SNPH,DYRK1A,EPB41L1,SORBS1,GABRB3,PPARGC1A,GNAO1,RAPGEF1,PTPN5,KCND2,MBNL1,MYO5A,NPTX1,NLGN3,ANKRD16,NXPH1,PKN2,SNRK,RDX,SLC25A36,SLC1A2,SLC6A8,CPEB4,SORCS3,SP4,PEG10,NKAIN2,NCDN,FBXW11,HEY2,RBFOX2,OSBP2,SF1,ZIC1,PCBP4" MicroRNA "ACTGTAG,MIR-139:MSigDB" "ACTGTAG,MIR-139:MSigDB" MSigDB 2.52E-24 1.42E-20 5.45E-24 5.02E-23 42 120 "TAOK1,PCDH10,LRCH2,ANK2,ZBTB10,ATP2B2,CDC42,CACNA2D2,DMD,TSPAN5,EIF4G2,STAU2,FREM1,PPARGC1A,GRM1,HMGCR,MAP2,MAT2A,MEIS2,NPTX1,PDE3A,PDE4A,PMP22,SCHIP1,NXPH1,PPP3CB,ZNF532,ATXN1,LRFN5,WDR47,CPEB4,SMARCA4,TMCC1,SOX1,SOX5,CDK19,TROVE2,TCF12,WASHC4,FBXL16,NDRG4,PAK5" MicroRNA hsa-miR-149-5p:Functional MTI Functional MTI miRTarbase 2.64E-24 1.48E-20 5.69E-24 5.24E-23 77 397 "ACLY,CLK4,TBC1D14,OSBPL8,ARRB2,CCAR2,KIF1A,BID,NIPA1,FOXK1,CBS,LRRFIP1,ARHGAP22,COG1,ZNF385A,LRIG1,CSNK1E,PPP6R2,MATR3,DBN1,ELMSAN1,ATN1,EEF1D,EIF5,DCTN4,PLEKHO1,DMTN,FDFT1,FGFR1,AGAP3,FOXM1,DCTN2,GFER,ZNF276,RNPS1,TOX3,GLUL,IBA57,MID1,GIT1,NACA,NFIX,NPTX1,PBX1,PDE1B,FAM98B,FAM216A,KANSL1,PTAFR,RBBP6,RGS12,LGI2,RAVER2,RPL15,SBF1,PEX26,DHX30,CDK5RAP2,ZSWIM8,RAP1GAP2,ZNF621,SUPT5H,PRRC2C,SATB2,OBSL1,NSD1,FBXL16,LRRC8A,KCTD2,ZNF346,ZNF610,MICAL1,SPHK2,TMEM237,WNK1,NUP214,FXR1" MicroRNA hsa-miR-3135:mirSVR_highEffct hsa-miR-3135:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-24 1.60E-20 6.13E-24 5.64E-23 63 274 "ADD3,NLGN4X,AMPH,DDX3Y,SLC4A4,MTMR7,C1orf52,SLC4A8,HS3ST5,PNKD,MATR3,HP1BP3,SV2B,DOCK2,RGS17,DUSP27,NBEA,FYB1,DKK3,TUBA8,LNX1,ADGRA3,PLCD4,GRID1,HTR5A,FAM95B1,RAB41,IL6R,SYT9,SLCO1C1,DNHD1,MAPKAP1,EPB41L4B,GON4L,SNRK,MTMR10,GTDC1,SLC25A36,TMLHE,FBXW7,TRAPPC13,SCN8A,NLGN4Y,DHX30,FAM126B,KDM3A,DDHD2,CAMTA1,UNC5D,TMEM136,TCF7L2,ZEB1,PUM2,GPRIN3,TK2,CADM1,SLC35A4,FLRT1,CFAP298,ZBTB14,ZNF189,PIANP,CPNE4" MicroRNA hsa-miR-575:PITA hsa-miR-575:PITA_TOP PITA 2.88E-24 1.62E-20 6.21E-24 5.72E-23 52 188 "CSMD3,PCDH19,ANK3,TMEM263,CHRD,SLC4A4,ATP2B1,CACNA2D1,PTBP2,LRBA,SLC35F1,CREB5,SLITRK5,TOX,DBN1,SACS,DNM1L,PHC2,EFNB3,EIF5,EPHB1,FGF1,PRKAG2,GPD1,TMEM121B,PCLO,GRIA2,NEGR1,KCNA1,KCND1,KCND2,MAP2,PDE1C,PDE1B,NXPH1,LRRN3,RGS3,SCN2B,FAM19A1,SCAF8,CHD9,FAM81A,ADAMTS17,FBXW11,PUM2,FNDC5,ZBTB38,CADM2,PCBP4,WNK3,HNRNPA3,ACTR3B" MicroRNA hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 3.15E-24 1.77E-20 6.79E-24 6.25E-23 83 455 "FZD9,SORCS2,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BACH1,BCL2L2,LDHD,FOXK1,ZBED1,DIS3L,CLCN3,IFFO1,ZNF385A,ENTPD4,SOCS5,UBXN2A,KIAA0513,DNAL1,PLEKHM1,RABGAP1L,NR1D2,SLC12A6,DPYSL2,SH3GLB1,APH1A,ABI2,IRAK4,ELAVL2,BSCL2,TLR7,GTF2IRD2,SUCO,SEC23B,TRAF3IP2,KIAA1841,SRCAP,CRCP,CECR2,GRB10,MFSD2A,HAS2,HMGB1,KCND3,GPR155,MBNL1,DDR2,PDPK1,PFKP,TMEM38A,ZNF426,PRKACB,SLC22A23,OCIAD1,RBBP6,ZNF532,C12orf49,TMEM100,FOXRED2,SBF1,DRAXIN,HSPA4L,KIF13A,SON,SP2,EMC1,STAC2,WWC1,SATB2,PSD3,GPRIN3,ZMAT3,ARL10,CBX5,PARD3,RGMB,NR2C2,ZNF70,CADM2,MPPE1" MicroRNA hsa-miR-107:Functional MTI Functional MTI miRTarbase 3.29E-24 1.85E-20 7.09E-24 6.53E-23 66 300 "ADD2,AXIN2,ADORA3,SEMA6A,OGT,ZBTB10,NUMB,DOCK11,DST,MTMR3,RUNX1T1,CCNT1,CDC42,CHGA,CHRM1,TBPL1,CLOCK,CSNK1G3,VCAN,PPP1R16B,RIMS3,TMEM170A,DAPK1,YTHDC1,COPS7A,GUCD1,G3BP2,DMPK,FCF1,YAF2,PLEKHA1,EN2,ZNF585B,TUBA1B,ANKFY1,GABRB1,CAB39,EML4,IDH3A,JAK1,MDM4,ZNF680,MYBPC1,NF1,NFIA,PCSK5,ENPP2,PIK3R1,PPP2R5C,CNNM2,RBBP6,ZDHHC4,FBXW7,CLIP1,SALL1,SH3GL2,CPEB3,SMARCE1,GANAB,DICER1,TGFBR3,NACC2,TJP1,AMOT,ZBTB38,DHX33" MicroRNA hsa-miR-934:PITA hsa-miR-934:PITA_TOP PITA 3.29E-24 1.85E-20 7.09E-24 6.53E-23 38 97 "ALCAM,ATP2A2,RUNX1T1,DCLK1,MAGI1,KMT2C,SLC35F1,CEP170,DLG3,EML1,EPB41L1,GPHN,WAC,ACSL4,FOXO3,AFF2,GK,NEGR1,AGFG1,KCNA1,KCND2,KCNMA1,INSYN2,NOVA1,LRRN3,KANSL1,FAM120C,OXR1,MSANTD2,SLC1A2,RCOR3,ZCCHC24,SYT4,TRIM2,ZBTB14,ZFAND5,EVI5,WNK3" MicroRNA hsa-miR-1291:mirSVR_highEffct hsa-miR-1291:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-24 1.94E-20 7.45E-24 6.86E-23 74 371 "GALNT13,MTUS1,OGT,PLA2G4C,ADAM23,SYNJ1,CACNA1G,SYT6,RAB28,DNAJB5,SEC24C,NRSN1,GIT2,DBN1,DCC,NYAP1,DYNC1I1,YAF2,TESK2,SLC9B2,SPSB4,SGIP1,ARPP21,ZNF638,INSM2,GPM6A,GRIA2,LINGO1,ATXN2L,VSIG4,ELOVL5,ZDHHC15,CPT1C,OPALIN,SCIN,LRRTM3,ITGA7,VWA5A,NF1,VWA2,SLC11A2,NUCB2,PNMA3,SCHIP1,PILRA,MED1,PTAFR,TMEM260,RALGDS,ERI2,CARF,GSTCD,EPHA10,LRRK2,LGR4,NTNG1,ZNF365,FAM214B,TMEM132D,ATF7IP,SLC22A4,ABTB1,OGDHL,UNC80,SON,SYNE1,TF,TIAM1,ERCC6L2,RGMB,RPL7L1,FRRS1L,EMSY,PDSS2" MicroRNA hsa-miR-216a-5p:TargetScan hsa-miR-216a-5p TargetScan 3.72E-24 2.09E-20 8.01E-24 7.37E-23 62 267 "CLK4,ARID1A,CSMD3,PTCHD1,GOLGA7B,LRRC4C,NCOA1,DST,CDH2,L3MBTL4,PLAA,NIPBL,COL9A1,APPL1,PHF14,CTH,MAGI2,KLHL3,PDCD6IP,DTNA,ELAVL2,OLIG2,EPHA5,FDFT1,ANKFY1,PNMA2,GABRA1,GFRA1,MSL3,PARD3B,RFFL,PTPRT,IL1RAPL1,KLF12,HLF,HMGB1,HNF4G,C5orf24,JAK2,CLVS2,MITF,MMP16,CDK14,MARCH1,NTNG1,NLGN1,CPEB4,EPC1,CXXC4,RIMS1,KIF21B,KDM3A,ERC1,ARHGAP26,CUX2,BHLHB9,CADM1,FRRS1L,CADM2,LRP8,NAV3,RGS7BP" MicroRNA hsa-miR-517c:mirSVR_highEffct hsa-miR-517c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.89E-24 2.18E-20 8.37E-24 7.71E-23 61 259 "FMNL2,ELFN2,SLITRK1,SNX32,KCTD16,ADGRF5,ALCAM,MIER1,CDK5R1,LURAP1,DGKI,B4GALT6,QKI,ABI3BP,ZNF521,GAPVD1,KIF26A,LONRF1,DBN1,SMG7,NR1D2,RASGRP1,EGFR,ELAVL2,KCNMB2,PRMT5,POLR1B,ARFIP1,AHDC1,GGT7,GHR,HPGDS,GRIA2,GRIA4,MSL1,LRRTM3,ITPKB,JAK2,OLFM3,STMN1,ERICH3,NFIA,CDK14,NUDT11,SYNDIG1,SLCO1A2,SMARCE1,MBD5,TMCC1,TAB2,CEP68,TMEM150C,WWC1,AP4E1,SLC44A1,TJP1,TNS1,USP1,EML6,CASC15,CBLN2" MicroRNA "GACAATC,MIR-219:MSigDB" "GACAATC,MIR-219:MSigDB" MSigDB 4.15E-24 2.33E-20 8.92E-24 8.21E-23 44 134 "KCNH8,FMNL2,ADD2,RTL9,MRTFA,SEMA4G,NCOA1,CAMK2G,PHF19,DNAJC6,CPEB2,EGR3,EYA1,NEK6,PCDH17,PPARGC1A,TTBK1,MAPT,ZC3H12B,OCRL,ZNF827,PDE4D,PDGFRA,PURG,PDZRN4,TRHDE,ING3,SNRK,RORB,SOX6,ITSN1,CPEB3,NTNG1,BTBD7,ZCCHC24,SP4,KIF1B,MCF2L2,GSE1,SYT5,TACC1,NR2C2,UBE3A,SLC30A4" MicroRNA hsa-miR-484:PITA hsa-miR-484:PITA_TOP PITA 4.25E-24 2.39E-20 9.14E-24 8.42E-23 47 154 "PCDH19,ANK1,SEMA4G,FMNL3,CBARP,CNTFR,SEC24C,RIMS2,RHOBTB1,DLG2,DPP6,DPYSL2,PHC2,EGR3,EIF4G2,RASGRP2,RTN3,FGF1,FHL1,UBE2E3,GAP43,SPIN1,GRB10,MAP4K5,KLF12,ZIC5,MAP2,GIT1,NFIA,RETREG1,CEP41,TMEM260,PTPRE,BSDC1,RET,PRRT2,GTDC1,CYB561D1,SLC6A1,SLC20A2,SOX5,MYCBP2,TBL1X,THRA,TRPS1,ZIC1,TMEM237" MicroRNA "CTCTGGA,MIR-525:MSigDB" "CTCTGGA,MIR-525:MSigDB" MSigDB 4.86E-24 2.73E-20 1.05E-23 9.62E-23 45 141 "FZD9,PCDH19,OGT,BCL7A,BSN,CAMK2A,CAMK2G,CAPN3,SEPT7,STOML1,CLTB,QKI,NCOR2,TMCC2,RBM12,GFRA2,CDH20,MEIS2,NOVA1,SLC11A2,NUMA1,ZNF655,HMGCLL1,MAPKAP1,TNPO2,PPP2R5E,MDGA2,ATG16L1,RNF220,SEMA6D,ATXN1,ARHGEF40,SON,FNBP1,POGZ,SMOC1,SATB2,NSD1,PUM2,ZFP91,TPM3,WNT7A,PPP1R3F,SNX27,PAK5" MicroRNA "CTCTGGA,MIR-520A:MSigDB" "CTCTGGA,MIR-520A:MSigDB" MSigDB 4.86E-24 2.73E-20 1.05E-23 9.62E-23 45 141 "FZD9,PCDH19,OGT,BCL7A,BSN,CAMK2A,CAMK2G,CAPN3,SEPT7,STOML1,CLTB,QKI,NCOR2,TMCC2,RBM12,GFRA2,CDH20,MEIS2,NOVA1,SLC11A2,NUMA1,ZNF655,HMGCLL1,MAPKAP1,TNPO2,PPP2R5E,MDGA2,ATG16L1,RNF220,SEMA6D,ATXN1,ARHGEF40,SON,FNBP1,POGZ,SMOC1,SATB2,NSD1,PUM2,ZFP91,TPM3,WNT7A,PPP1R3F,SNX27,PAK5" MicroRNA hsa-miR-6780a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.95E-24 2.78E-20 1.06E-23 9.79E-23 52 190 "SLC25A25,TNRC6C,APP,SLC7A14,LDLRAD4,RUNX1T1,REPS2,LRRFIP1,SLC22A6,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,IP6K1,TMCC2,DPYSL2,NCALD,ANKMY1,REEP2,TAOK3,SCML2,CELF1,HHIPL1,ZNF638,GRIK3,GRM8,PTGDR2,CLVS2,SYTL4,MBNL1,GDAP1L1,PKM,POLG,PRKCB,ZNF844,BSDC1,ELP2,ASIC4,ZFP30,SLC6A8,SEPT8,ACSBG1,VPS13A,TGFBR3,RBFOX2,UGT8,ZNF154,AMZ1,UPF3A,WNK1,FRMD6" MicroRNA hsa-miR-1537:mirSVR_highEffct hsa-miR-1537:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.01E-24 2.81E-20 1.08E-23 9.90E-23 71 346 "ADCY8,BRAP,PWWP2A,AMPH,TNRC6C,USP37,SHTN1,DDX3Y,TTLL9,BCHE,BMP7,ARHGEF2,QKI,HS3ST5,MICAL2,RIPOR2,KIAA0586,GIT2,SNAP91,SPOCK3,DPYSL2,DTNA,YAF2,EIF1,TUBB3,FGF13,EVL,SORBS1,CHL1,CAB39,GCNT2,ARFIP1,ZNF638,GNAO1,GRM1,UBE2QL1,IL6R,ZNF678,KLC1,SMAD1,LRP1B,NDUFA5,PCSK5,PPM1B,DBX2,SLC6A15,RPRD1A,NLGN4Y,SGK1,DOCK10,WDR47,PDZRN3,LMO3,ATP10B,POGZ,ADHFE1,ADGRL3,ITGB3BP,AKTIP,RIMBP2,ELP5,TRO,PITPNB,WIPF1,KLC2,ANKS1B,UPF3A,EMSY,ITM2C,PDSS2,PHTF2" MicroRNA hsa-miR-1274a:PITA hsa-miR-1274a:PITA_TOP PITA 5.43E-24 3.05E-20 1.17E-23 1.07E-22 46 148 "SNX30,MTMR3,BSN,CACNB2,NRXN1,FEZ1,CSNK1G3,G3BP2,NR1D2,FAM135B,EMX2,SCML2,PCDH17,RFFL,FAM19A2,ADAMTS6,BACH2,MIER3,HNRNPK,SMAP1,KCNA1,GPR62,KCNN2,ARHGAP12,NNAT,NOVA1,PRTG,CDK14,MED1,CNNM2,TMEM260,PTPRD,ATP8B4,SCN3A,LRRTM4,COPZ1,MYT1L,RGL1,TBL1X,SATB2,SLC44A1,TRPC3,UBE3A,TMEM237,SNX27,SLC4A10" MicroRNA hsa-miR-1269:PITA hsa-miR-1269:PITA_TOP PITA 5.71E-24 3.20E-20 1.22E-23 1.13E-22 41 116 "SLITRK1,BACH1,LGI1,QKI,AHCTF1,ZNF385A,CLOCK,CREB5,YTHDC1,DYRK1A,EMX2,OLFM1,NPTN,CAB39,AHCYL1,PCDH17,RAPGEF4,GRIK2,IL1RAPL1,ZHX1,NEUROD1,PDE4D,C11orf49,PMP22,RAP1GDS1,FBXO11,SNAP25,SPTB,EPB41L3,NSFL1C,NECAB1,ANKRD28,ANO4,TCF4,TCF12,ZFPM2,RIMBP2,TMEM237,WNK1,NAV3,SLC4A10" MicroRNA hsa-miR-1243:PITA hsa-miR-1243:PITA_TOP PITA 5.81E-24 3.26E-20 1.24E-23 1.15E-22 47 155 "ARID1A,ZNF608,MARCH3,SLC4A4,CDC42,CLCN4,FAM19A5,DNAJB5,AKAP7,CREB5,ERC2,IST1,DNAJC6,MAGI2,RAB39B,MBNL2,EGR3,RGS17,ERBB4,EYA1,SUCO,OGA,PPARGC1A,TOX3,GRIA2,IGF1,NAP1L3,NEUROD1,CNOT4,OPCML,PCDH9,NLGN3,SEMA5B,HMGCLL1,VSTM2L,FEZF2,RXRA,SALL1,PEG10,ZC3H4,ANKRD28,HHIP,WBP2,TMEM237,WNK3,RGS7BP,SOCS4" MicroRNA hsa-miR-3650:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-24 3.26E-20 1.24E-23 1.15E-22 47 155 "XKR4,PTCHD1,CARNS1,MARCH4,BCAS1,FOXK1,CCNT1,KIAA1549L,TMEM184B,IGLON5,AKAP5,SLC35F1,PYGO1,DCAF8,DBT,TMEM130,PLEKHA1,EN2,COQ7,ATP13A4,ZBED3,HHIPL1,GLI2,DIPK1C,AP4S1,MAP2,PPM1L,MYO5A,SPATA6,PRKCB,MAPK10,RAB5B,SLC25A36,PGBD4,SGK1,RPH3A,SLC2A5,KIF13A,LHPP,ZC3H4,FAM208A,TMEM151B,NR2E1,TPD52,PORCN,KCNK12,ZDHHC20" MicroRNA "TGTATGA,MIR-485-3P:MSigDB" "TGTATGA,MIR-485-3P:MSigDB" MSigDB 5.85E-24 3.29E-20 1.25E-23 1.16E-22 44 135 "ARID1A,ARHGAP20,ANK3,API5,PPP4R4,FOXK1,RUNX1T1,ZMYM4,NRXN1,TMEM184B,CNR1,GDA,SNPH,HDAC4,DAPK1,MAGI2,DYRK1A,YAF2,UBE2E3,ZMAT1,GAD2,CPLX2,PPARGC1A,GPM6A,STMN2,GRID1,NR3C1,KCNMA1,MEIS2,PDE4D,PURG,NXPH1,RBBP6,RFX3,RNF220,KIF21A,SOX11,GANAB,C3orf70,SYPL1,TBX15,PUM2,SIRT1,ZIC2" MicroRNA hsa-miR-184:mirSVR_highEffct hsa-miR-184:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.95E-24 3.34E-20 1.27E-23 1.17E-22 56 221 "KIAA1211,KIDINS220,KCTD16,PLA2G6,PCDH10,SUGT1P4-STRA6LP-CCDC180,EPB41L5,MIER1,MARCH3,CCAR2,CAMK2B,TRIM41,VXN,TAOK2,CNGA3,ANKRD44,ARHGEF10,ARHGAP24,BLOC1S6,DPP6,DTNA,SIDT2,ELN,EPB41L2,NRN1,ZNF589,FGF14,SCARA3,WDR83,AKAP3,UFM1,GABRB1,B4GALNT1,MAT2A,MBP,NRCAM,PDE4B,HMGCLL1,PLTP,APTX,WDR25,RNASEL,MEG3,NTNG1,SLA,SLC11A1,ADHFE1,SULF2,TMEM150C,SYPL1,CUX2,ZFPM2,LRRC8A,SF1,FMN2,MEIS3" MicroRNA hsa-miR-623:PITA hsa-miR-623:PITA_TOP PITA 6.83E-24 3.84E-20 1.46E-23 1.35E-22 43 129 "CCDC85A,GPR158,CNTNAP1,DDX3Y,SLC4A4,CACNA1A,CALM1,DCLK1,TAOK2,HAPLN1,RIMS4,EBF1,CELSR3,EIF1,NCALD,RND1,GPR19,CIT,RNF165,ADAMTS6,NKD1,CYP27C1,MBNL1,MEIS1,MEIS2,NTRK3,GPR85,PIK3R1,PTPRD,PRRT2,ATXN1,ZNF821,NLGN1,SLC12A2,EPC1,UNC5B,SEPT3,TRIM2,TCF12,RBFOX2,ZNF384,MVB12B,CERS6" MicroRNA hsa-miR-147a:Functional MTI Functional MTI miRTarbase 7.47E-24 4.20E-20 1.60E-23 1.47E-22 46 149 "SEMA6A,CARNS1,CACNA1A,RUNX1T1,SLC22A6,TMEM184B,IGLON5,CLOCK,CREB5,NCAN,PPP1R16B,DCAF8,JAKMIP2,TMEM130,BLOC1S6,DMD,DMTF1,EN2,EPHA5,MRPL37,FGF14,CAMKK2,GFRA1,CBX1,PRRC2B,IL1RAPL1,NKD1,KCNB1,IPO5,MAP2,MITF,HS6ST3,NOS1,ZNF655,PLP1,SDK2,TTLL7,SATB1,NCDN,ZEB1,HIF3A,VSNL1,PORCN,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-517b:mirSVR_highEffct hsa-miR-517b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.06E-24 4.53E-20 1.72E-23 1.59E-22 48 163 "FMNL2,SNX32,CASC2,NRXN1,ABI3BP,AHCTF1,ERC2,BOC,MATR3,DNAJC6,GSDME,EGFR,CLVS1,CORO2B,ATP2C1,ZNF559,DISC1,HPGDS,GLRB,GPD2,GRIK2,MSL1,LRRTM3,OLFM3,KCNJ16,ERICH3,NEUROD1,PFKP,PPP2R5C,VPS13C,PTHLH,PTPRD,PTX3,RASGRF2,C12orf49,SHC4,SLCO1A2,SMARCE1,TMEM150C,TBX15,TSC1,FAM181B,TMEM198,WNK1,PRDM8,LINC00632,MPPE1,CPNE4" MicroRNA hsa-miR-6788-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-24 4.67E-20 1.78E-23 1.64E-22 89 521 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,DDX3Y,SYNJ2,ISPD,SLC16A4,MYOM2,CHRNB2,EPS15L1,SUMF2,BTF3L4,MFSD4A,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,ABI2,PLEKHA1,MRNIP,MTSS1L,IGSF6,ANKFY1,PNMA2,TRAF3IP2,NCKAP1,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,DOCK7,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,FTO,SDK2,RETREG2,FAT3,PPARA,MTMR10,PTPRE,RAB5B,CEP97,PLEKHB2,SETD5,KLHDC8A,SOX6,MYO18A,CLSTN1,SLC1A2,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,AJAP1,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RFTN2,RPRM,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,SNX27" MicroRNA hsa-miR-151-3p:PITA hsa-miR-151-3p:PITA_TOP PITA 8.53E-24 4.79E-20 1.82E-23 1.68E-22 39 105 "PPFIA2,SPAG9,ARMC8,RGS6,SOCS5,SRGAP3,MBNL2,EIF4G2,DLC1,ZMAT1,CHL1,GHR,PCLO,GRB10,GRM3,PSIP1,KLF12,MIER3,BRINP3,LRRTM1,PKN2,RYR3,TRA2B,HSPA4L,YPEL4,CLASP2,LARP4,LRRC4,VAMP1,ZFPM2,TRPS1,TBC1D15,ZFAND5,SMARCAD1,SYNC,NAV3,WIPF2,FXR1,NETO2" MicroRNA "GTGACTT,MIR-224:MSigDB" "GTGACTT,MIR-224:MSigDB" MSigDB 1.03E-23 5.76E-20 2.19E-23 2.02E-22 46 150 "SLC12A5,APBA2,API5,USP37,DDX3Y,SLC4A4,ATP1B3,CAST,CDC42,FOXN3,QKI,CREB5,DNM1,CPEB2,DPYSL2,EFNA3,MBNL2,ACSL4,AMOTL2,FAM49B,BRPF3,TCERG1,CIT,HMGCR,HES5,KCNMA1,STMN1,PAXBP1,MBNL1,PDGFRA,ZNF655,PTX3,ZFHX4,CASC3,TRA2B,ITSN1,KDM3A,ZNF423,SEPT3,SYP,ARHGEF12,PUM2,FNDC5,TRIM9,SMARCAD1,ZDHHC20" MicroRNA hsa-miR-532-3p:PITA hsa-miR-532-3p:PITA_TOP PITA 1.07E-23 6.03E-20 2.29E-23 2.11E-22 47 157 "ADCY6,ALCAM,CNTNAP1,APP,EIF4G3,ATP2B1,CAMK2G,CANX,CDH2,NRXN2,HECTD1,NIPBL,CRY2,G3BP2,WDR20,DMTF1,DYRK1A,PHC2,GPR61,KMT5B,ELAVL3,ETV1,WAC,ZIC4,NPTN,GABRA4,GAP43,PPARGC1A,ZIC5,PPM1L,NEXMIF,NFIX,NPTX1,PDE4D,CAMKV,IRX1,MAPK4,PSD,BSDC1,AMBRA1,NMNAT2,ANKRD12,EHBP1,ZNF384,EMSY,STMN4,MSRB3" MicroRNA hsa-miR-6868-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-23 6.86E-20 2.61E-23 2.40E-22 51 186 "RALGAPA1,XKR4,FMNL2,GALNT13,RNF157,ADD1,SPOP,CDC42BPA,SFMBT2,DDR1,LURAP1,LRRFIP1,B4GALT6,PLCXD3,TM9SF4,RIMS3,CPEB2,OPTN,RGS17,EMX2,EPHB1,ERBB2,ST3GAL6,ZMAT1,LYVE1,TCERG1,DIPK1C,NUDT21,NR3C1,HMGB1,HMGCR,NEGR1,KIF5A,LSAMP,MYO5A,RASGEF1B,PRKCB,SPDL1,SH3TC2,MSANTD2,KCNIP3,LRRTM4,ASIC4,ZFP30,EXOC7,KLHL4,SZT2,AHCYL2,TNS1,TPD52L2,SLC38A1" MicroRNA hsa-miR-100:mirSVR_lowEffct hsa-miR-100:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.25E-23 7.02E-20 2.67E-23 2.46E-22 53 201 "TAOK1,ZFAT,ARNTL,SYNJ1,SCAPER,MTMR3,MTMR2,LURAP1,KALRN,HINFP,UBXN2A,EDRF1,HDAC4,DBI,PLPPR4,NTM,PHF20L1,IRAK4,CAP2,NOP56,MEGF10,ALDH1L1,ADAM28,HNF4G,C2orf72,DOCK7,INSM1,LSS,MOG,MYO7A,BEST3,PURG,ING3,RAB39A,PRKCZ,EPDR1,PTPRN2,TTLL7,FBXO11,SLC8A2,SLC14A1,BTBD7,MYO16,KDM4C,TSPYL2,ST5,ANKRD28,SYNE1,TMPO,VLDLR,BEST1,GAL3ST3,URM1" MicroRNA hsa-miR-1262:PITA hsa-miR-1262:PITA_TOP PITA 1.38E-23 7.72E-20 2.93E-23 2.70E-22 43 131 "RTL9,SEMA4G,ATP2B3,SYNJ1,NRXN3,TOX,PLEKHM1,MAGI2,DPH1,MBNL2,EFEMP1,FGF13,MEX3B,AFF2,GNAS,PCLO,GRIN2D,GRM7,RNF165,HLF,ITGAV,MAT2A,NEXMIF,TCEAL5,NEUROD2,ZNF827,PCSK1,PLP1,PKIA,SNX22,ATXN1,SMPD3,TET1,TJP1,RBFOX2,FNDC5,USP1,BEST1,SF1,ZIC1,ZIC3,SYNC,NETO2" MicroRNA hsa-miR-1302:PITA hsa-miR-1302:PITA_TOP PITA 1.40E-23 7.88E-20 2.99E-23 2.75E-22 46 151 "NDRG2,FMNL2,TRMT9B,MARK4,SLC4A4,ATP2B2,CAMK2G,FMNL3,USP6,AKAP6,SLC35F1,DCAF8,C2CD2L,PTK2B,IQGAP2,TNRC6A,IL1RAPL1,MIER3,C5orf24,STMN1,KITLG,MDGA1,NEUROD2,NNAT,CNOT4,RETREG2,MED1,UHRF1BP1,FAM120C,FBXW7,LGR4,ATXN1,SCN4B,FBXO11,SLITRK3,RIMS1,ANKFN1,LHFPL4,ERC1,CDK19,TAB2,ACSL6,TRPS1,UBE3A,VSNL1,MAP3K12" MicroRNA hsa-miR-4455:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-23 8.16E-20 3.10E-23 2.85E-22 48 165 "PTCHD1,MARCH4,ARHGDIA,MARCH3,FOXK1,RAB3C,KIAA1549L,NCAN,PPP1R16B,PYGO1,DBT,DNAJC6,JAKMIP2,DMD,CDON,PLEKHA1,EN2,KATNAL1,FGF14,ZBED3,FAXC,GLI2,CBX1,DIPK1C,KCNQ3,MPP2,DBNL,MYO5A,PRKCB,MAPK10,SH3TC2,PRRT2,TTLL7,SETD5,PGBD4,RPH3A,NMNAT2,KIF1B,CAMTA2,ZC3H4,CUX2,ZEB1,TMEM151B,NACC2,NR2E1,TNR,PORCN,ZDHHC20" MicroRNA "GTGCCAT,MIR-183:MSigDB" "GTGCCAT,MIR-183:MSigDB" MSigDB 1.45E-23 8.16E-20 3.10E-23 2.85E-22 48 165 "SLITRK1,OSBPL8,OGT,PKP4,CHRD,CDK5R1,CFL2,SRSF11,CLCN3,QKI,CSNK1G3,KLHL3,RHOBTB1,SACS,CELSR3,ARFGAP2,EML4,NR3C1,BACH2,KCNK2,HECTD2,MBNL1,MEF2C,KCNK10,PDE4D,ING3,PPP2R5C,SLC22A23,USP47,RALGDS,SEMA6D,SMPD3,SOX6,PPM1E,SLITRK3,TET1,SNCB,LMO3,GSE1,TCF12,ZFPM2,SLC44A1,TMPO,RIMBP2,TPM1,TPM3,TUB,FRMD6" MicroRNA hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 1.45E-23 8.16E-20 3.10E-23 2.85E-22 48 165 "GOLGA7B,ALS2,ARNTL,MAP7,RUNX1T1,NUMBL,KMT2C,AHCTF1,CLOCK,CSF1,CSNK1G3,RIMS4,ERC2,IST1,CHRDL1,FAM135B,RBM12,ERGIC3,GABRB1,GABRB3,GFRA2,PCDH17,RNPS1,GRM5,BACH2,SCRT2,KCND3,MAP2,MSI1,NEUROD2,POU3F2,MDGA2,GTDC1,PBRM1,RPRD1A,ACER3,SCN4B,ITSN1,PEX26,MBD5,DIP2A,COBL,NR2C2,CADM1,BCL2L13,CLIP2,GAL3ST3,HNRNPA3" MicroRNA hsa-miR-548s:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-23 8.74E-20 3.31E-23 3.05E-22 79 427 "KIAA1324,GOLGA7B,C6orf89,GPAM,PDXK,ATP1A2,BACH1,CBS,CCNT1,RAB3C,AKAP6,LRIG1,CSNK1E,CTH,GREB1,MYADM,FGFR1OP2,KIAA0586,DBT,YTHDC1,BLOC1S6,RABGAP1L,SIDT2,MRO,COQ7,ZNF549,POLR1B,TRMO,GATM,CRCP,GLUL,LUZP2,ADAMTS8,DDX19B,HLF,ATCAY,ZNF678,CYP27C1,MAG,MAPT,MYO6,PABPC1L2A,SFR1,SLC11A2,TNPO2,MAPK8,PTPRB,MRPS18A,SNX22,SGSM1,PTGR2,RTKN,FOXRED2,HOGA1,MAGI3,URGCP,PREX2,PEX26,FAM126B,SOX5,KIF1B,DDN,LHPP,SSTR2,NEK4,SYT11,ALG1,WWC1,AGTPBP1,TBCEL,USP22,ZMAT3,TPM3,ZNF610,VLDLR,TBC1D15,ZNF70,RGMA,GAN" MicroRNA hsa-miR-599:PITA hsa-miR-599:PITA_TOP PITA 1.61E-23 9.04E-20 3.43E-23 3.16E-22 44 138 "SORCS1,GPR158,OGT,LRRC4C,SLC4A4,STX16,USP6,CNTFR,CEP170,DYRK1A,ANKRD13B,TAOK3,AGAP2,FOXO3,BRSK1,C15orf41,KDM2B,IGF1,C5orf24,RBPJ,MXI1,NEUROD2,NFIA,PDE3A,PDE4B,PDE4D,PTPRD,FAM120C,BSDC1,SOX11,SP4,CLASP2,SEPT3,ARHGEF9,UNC5D,SATB2,TCF12,TRPS1,FLRT2,SNX27,KAT6A,HNRNPA3,CERS6,JMJD1C" MicroRNA hsa-miR-590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-23 9.97E-20 3.78E-23 3.48E-22 75 390 "APC,KIAA1614,STX16,BACH1,CACNG1,PTBP2,CDC27,SLC24A2,LETMD1,BAG4,UBXN2A,USP6NL,YTHDC1,ZEB2,MYEF2,FARSB,SEMA3D,KMT5B,RASA4,PLEKHA1,C8orf37,EPB41L1,RAB9B,RTN3,WAC,AMOTL2,FOXG1,SEC23B,PCYOX1,FAM49B,MSANTD4,DKK3,NCKAP1,MALT1,ZNF276,RNPS1,PCDH11X,CBX1,GRIK4,NR3C1,MIER3,HNRNPK,IL6ST,ITPKB,LIMS1,MBNL1,CHIC1,TM6SF1,SESN3,MXI1,NUCB1,OLR1,PAH,SH3KBP1,MAPK8,SETD5,RPL15,FBXW7,FAM161B,ATXN1,TRA2B,SLC8A1,AGTPBP1,KIAA0930,ZEB1,KAT6B,TRPS1,SSBP2,ZFP37,WNK1,XKR7,LINC00632,PHTF2,JMJD1C,SSPN" MicroRNA "ATGAAGG,MIR-205:MSigDB" "ATGAAGG,MIR-205:MSigDB" MSigDB 1.79E-23 1.01E-19 3.81E-23 3.51E-22 45 145 "CANX,MAGI1,CHN1,B4GALT6,CLTC,QKI,CDC42BPB,DLG2,CPEB2,PHC2,EPB41,RTN3,SORBS1,ST6GALNAC3,PHYHIPL,JPH4,LRRC37A6P,GPM6A,KLF12,ACOT7,CLDN11,PDE3B,SEPT4,MED1,TMEM260,LRRK2,BTBD3,LIMS2,SCMH1,SP4,KIF1B,CDK19,GANAB,SEPT3,PLCB1,CAMSAP2,MGRN1,DMXL2,SATB2,NACC2,TRPM2,TRPS1,AMOT,ADAMTS9,SNX27" MicroRNA hsa-miR-197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-23 1.03E-19 3.89E-23 3.59E-22 77 409 "SERPINA3,ADAR,TAOK1,TRMT9B,CDK10,ARSE,ATP1A1,ATP1A2,ATP2A2,FOXN3,CPNE6,RAB28,AKAP6,CSNK1E,GAPVD1,KIAA0586,MAML1,DBT,SPATA2,MED24,DPH1,GNE,WDPCP,HIPK3,PIPOX,DLC1,FOXO3,TRMO,MPP6,HBS1L,ZNF274,SRCAP,GGT7,KIAA1958,GOLGB1,GPR26,PTPRT,GSTM5,RNFT2,DDX19B,IDH3B,KLC1,KPNA5,MSI1,MYO6,ZDHHC22,MINDY2,ZNF793,ZYG11B,C12orf49,RAVER2,SNX22,UEVLD,FBXW7,SH3BP2,NUBPL,PDZRN3,SOX11,CLUAP1,KIF1B,SPART,ZNF302,SS18,NEK4,FGD4,ZFR2,ATP11A,ALG1,AGTPBP1,CYB561A3,CBX5,ZNF384,ZNF708,ZNF70,WNK1,MSRB3,GAN" MicroRNA hsa-miR-197:PITA hsa-miR-197:PITA_TOP PITA 1.91E-23 1.07E-19 4.06E-23 3.74E-22 46 152 "RBM10,USP31,UNC5A,PCDH19,SEMA6A,CBLN1,SLC32A1,CTNND1,MTX3,GRIN3A,DNM1,DYRK1A,EBF1,EYA1,TAOK3,AGAP2,STAG2,CECR2,GRIA2,SMAP1,KCNA1,KCND2,STXBP5,MBNL1,NKX2-2,HCN1,PDGFRA,TMEM145,FBXW7,PPM1E,NLGN1,CCDC88A,SLC20A2,RIMS1,SOX11,PEG10,SS18,SYN1,TAL1,DOCK9,UBE3A,PITPNB,MEAF6,ZIC3,FZD3,PIANP" MicroRNA hsa-miR-4419b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-23 1.09E-19 4.11E-23 3.78E-22 86 497 "ABCF1,NDRG3,TXNDC16,KIF6,APAF1,AQP6,CDC14B,ATM,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,MFSD4A,SLC35F1,CLOCK,IPCEF1,UBXN2A,KIAA0513,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,KIF3A,AGBL5,IGF1,PLD5,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,PLEKHB2,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,WDTC1,CDK19,MCF2L2,LHPP,VAMP1,FAM208A,SLC19A3,AKNA,PCDHA6,TPM3,SSBP2,EVI5,URM1,SNX27,MPPE1" MicroRNA hsa-miR-6881-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-23 1.10E-19 4.14E-23 3.81E-22 56 226 "SLC25A25,GRAMD1B,TNRC6C,APP,SLC7A14,ATP2B3,LDLRAD4,RUNX1T1,LRRFIP1,DIS3L,SLC22A6,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,IP6K1,SPATA2,SMG7,TMCC2,DPYSL2,RCAN1,ANKMY1,REEP2,SCML2,HHIPL1,RAPGEF6,ZNF638,RAPGEF1,GRIK3,GRM8,PTGDR2,HMGB1,CYP27C1,SYTL4,MBNL1,NUCB1,GNG2,GDAP1L1,POLG,PRKCB,PIGG,ZNF844,ELP2,ASIC4,ZFP30,MYO18A,SLC6A8,SEPT8,ACSBG1,VPS13A,TGFBR3,RBFOX2,UGT8,AMZ1,FRMD6" MicroRNA hsa-miR-518c:mirSVR_highEffct hsa-miR-518c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.98E-23 1.11E-19 4.21E-23 3.87E-22 62 275 "TTYH1,TKTL1,AXIN2,LRFN2,ZNF608,PCDH19,ANK1,PPFIA1,CASK,CFAP410,LGI1,CHGA,PPT2,AKAP6,SMARCAL1,ACBD5,SOCS5,DRD1,DTNA,EDN1,ANKRD13B,GMPR2,ACSL4,GORAB,FHL1,TACC2,NSG2,SYT17,KDM2B,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,RTL5,ZC3H12B,NDUFA5,ZNF827,SH3KBP1,PPP3CB,APTX,TMEM255A,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,TBCEL,NSD1,TGFBR3,HEY2,KAT6B,TPD52L2,TSN,PLEKHH2,KCNK12,EMSY,PRDM2,PRTFDC1,TUBA1A,PARP11" MicroRNA hsa-miR-425*:mirSVR_highEffct hsa-miR-425*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.09E-23 1.17E-19 4.43E-23 4.08E-22 51 188 "ADRB2,LRCH2,EPB41L5,LINC00173,TTLL9,BTK,BRSK2,EPS15L1,NRXN2,ARMC8,COL9A1,SEC31B,CLIP3,UBXN2A,DOCK4,HS3ST2,DTNA,ANKRD46,KLHL5,GPHN,FDFT1,IGSF5,CBX1,GABARAPL2,KCND1,MYO9A,NCAM1,NUCB2,PCSK1,PFKFB4,GDAP1L1,SMIM7,C11orf49,SCHIP1,MED1,MTMR10,FAM192A,DRAXIN,NUBPL,ZNF365,MAST1,SOX5,ZCCHC24,NPAS3,TAB2,SEPT8,TACR1,TMEFF2,ZNF138,TRAM2-AS1,NETO1" MicroRNA hsa-miR-551a:mirSVR_lowEffct hsa-miR-551a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 2.21E-23 1.24E-19 4.69E-23 4.32E-22 63 284 "KDM5D,CSMD2,DPP10,DACT3,CACNA1B,CACNA1D,RUNX1T1,P2RX6,NEURL1,ZBED1,JAM2,PPT2,COL4A5,PNKD,APPL1,CENPL,MFAP3L,CCDC3,KBTBD11,MAMLD1,HIPK3,ABI2,GOLGA7,VPS13B,ERBB2,ERBB4,ANKMY1,ZSCAN30,FGFR1,POMT1,DISC1,ADAM28,LNX1,CNDP1,SYNPO,FAAP20,IRF8,DOCK7,SFXN5,MBP,MEIS1,SCG3,OGG1,PDE4B,ING3,PPP2R2B,GTDC1,ABCA11P,KCNIP3,CLSTN1,FAM81A,SNRPN,KDM4B,ZC3H13,ARHGEF9,COBL,TMEM136,SYNE1,ZIC3,RNF103,EPM2A,FBXO36,KLHDC1" MicroRNA hsa-miR-3929:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-23 1.25E-19 4.71E-23 4.34E-22 86 498 "ABCF1,NDRG3,TXNDC16,KIF6,APAF1,AQP6,CDC14B,ATM,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,MFSD4A,SLC35F1,CLOCK,IPCEF1,UBXN2A,KIAA0513,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,KIF3A,AGBL5,IGF1,PLD5,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,PLEKHB2,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,WDTC1,CDK19,MCF2L2,LHPP,VAMP1,FAM208A,SLC19A3,AKNA,PCDHA6,TPM3,SSBP2,EVI5,URM1,SNX27,MPPE1" MicroRNA hsa-miR-4478:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-23 1.25E-19 4.71E-23 4.34E-22 86 498 "ABCF1,NDRG3,TXNDC16,KIF6,APAF1,AQP6,CDC14B,ATM,ZNF583,ZNF555,PTBP2,SLC16A4,CBFA2T2,NRXN3,AKAP6,SUMF2,MFSD4A,SLC35F1,CLOCK,IPCEF1,UBXN2A,KIAA0513,TMEM170A,ELMSAN1,SGSM2,DNAH9,SLC29A4,GNE,SYT15,HEYL,TMTC1,RASA4,IRAK4,PLEKHA1,MRNIP,VPS26C,ZNF585B,FKTN,ZNF589,ATP13A4,TRMO,ZBED3,CRCP,GPR75,GLUL,ZNF638,KIF3A,AGBL5,IGF1,PLD5,KLHL23,SMAD9,MATN3,PPM1L,N6AMT1,NFYA,SLC11A2,PAX6,ZDHHC8,APTX,MTMR10,TMEM145,QDPR,PLEKHB2,GSTCD,PTGR2,AMBRA1,SLC2A5,PEX26,EPN2,SEPHS1,WDTC1,CDK19,MCF2L2,LHPP,VAMP1,FAM208A,SLC19A3,AKNA,PCDHA6,TPM3,SSBP2,EVI5,URM1,SNX27,MPPE1" MicroRNA hsa-miR-548ah-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-23 1.33E-19 5.02E-23 4.62E-22 67 319 "ADAR,FMNL2,FZD9,SEMA7A,CAPRIN2,NIPA1,FOXK1,SRSF11,EPS15L1,ZFYVE9,BTF3L4,RTTN,CPS1,APPL1,UBXN2A,DCAF8,KIAA0513,FBXL5,RAB39B,HIPK3,FEM1B,FCF1,SH3GLB1,KMT5B,ELAVL2,CERCAM,F3,MSANTD4,C15orf41,FAXC,SESN1,CRCP,CBX1,LUZP2,FUT10,GRB10,NR3C1,RBPJ,KCNB1,STMN1,MDM4,KCNK10,PFKFB3,PFKP,ZFYVE21,LRP12,SH3KBP1,PRKCB,SLC22A23,PXK,PEX2,RAB5B,CEP97,ATXN1,TMEM200C,RUFY2,FAM126B,SP4,TAF6,SATB2,NACC2,TPM4,RGMB,EMSY,ADAMTS9,ITM2C,WNK3" MicroRNA hsa-miR-924:PITA hsa-miR-924:PITA_TOP PITA 2.47E-23 1.39E-19 5.22E-23 4.81E-22 45 146 "DSCAML1,SPOP,CDC42BPA,API5,CDC14B,BSN,NRXN1,CREB5,NCOR2,TENM4,DOCK4,FRMPD4,NYAP1,DSCAM,GOLT1B,EBF1,RBM12,APH1A,RGS17,FOXO3,GUCY1A2,ZIC5,MAP2,MEIS2,ZC3H12B,NDP,HCN1,PDE3A,SERPINE2,PIK3R1,PMP22,RGS4,SEMA6D,FAM19A1,FAM214B,SOX11,ARHGAP26,POPDC3,CUX2,TMEM121,CADM1,SLAIN1,FLRT2,ZIC3,CELF4" MicroRNA hsa-miR-642:PITA hsa-miR-642:PITA_TOP PITA 2.60E-23 1.46E-19 5.50E-23 5.06E-22 48 167 "CSMD3,PCDH19,CAPRIN2,ATP2B1,INA,CDH2,CLCN3,LRIG1,ZEB2,DYRK1A,EBF1,EMX2,EPHB1,ERBB4,FGF1,ARFGAP2,MEGF11,AHCYL1,PCDH17,PPARGC1A,RND1,GPD2,NEGR1,AGFG1,BRINP3,LRRTM3,KIF5A,LSS,PDGFRA,PIK3R1,EPB41L4B,PPP3CA,TMEM260,ZFHX4,ITSN1,FAM214B,FAM126B,SOX5,KDM4C,SS18,ERBIN,NCDN,SEPT3,AP4E1,LRRC8A,TNS1,ZFAND5,WNK3" MicroRNA "ACTGAAA,MIR-30E-3P:MSigDB" "ACTGAAA,MIR-30E-3P:MSigDB" MSigDB 2.72E-23 1.53E-19 5.75E-23 5.29E-22 51 189 "OSBPL6,APC,ATP1A1,CANX,RUNX1T1,CCKBR,USP6,ZFYVE9,QKI,CSNK1E,CSNK1G3,IPCEF1,DSCAM,SH3GLB1,EIF1,ERBB4,DNAJC27,ZIC4,MED12L,DBF4,NR3C1,PSIP1,NEGR1,LRRTM1,MARK1,MEF2C,NRCAM,PRRX1,PPP2R5E,RAD51D,ARID4A,DBX2,RGS7,PBRM1,ROBO1,FBXW7,RYR3,ATXN1,SH3GL3,SLITRK3,MYT1L,NKAIN2,AHCYL2,AP4E1,NR2C2,FNDC5,HIRA,USP1,RICTOR,USP32P2,FXR1" MicroRNA "ACTGAAA,MIR-30A-3P:MSigDB" "ACTGAAA,MIR-30A-3P:MSigDB" MSigDB 2.72E-23 1.53E-19 5.75E-23 5.29E-22 51 189 "OSBPL6,APC,ATP1A1,CANX,RUNX1T1,CCKBR,USP6,ZFYVE9,QKI,CSNK1E,CSNK1G3,IPCEF1,DSCAM,SH3GLB1,EIF1,ERBB4,DNAJC27,ZIC4,MED12L,DBF4,NR3C1,PSIP1,NEGR1,LRRTM1,MARK1,MEF2C,NRCAM,PRRX1,PPP2R5E,RAD51D,ARID4A,DBX2,RGS7,PBRM1,ROBO1,FBXW7,RYR3,ATXN1,SH3GL3,SLITRK3,MYT1L,NKAIN2,AHCYL2,AP4E1,NR2C2,FNDC5,HIRA,USP1,RICTOR,USP32P2,FXR1" MicroRNA hsa-miR-3609:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-23 1.60E-19 6.03E-23 5.55E-22 67 320 "ADAR,FMNL2,FZD9,SEMA7A,CAPRIN2,NIPA1,FOXK1,SRSF11,EPS15L1,ZFYVE9,BTF3L4,RTTN,CPS1,APPL1,UBXN2A,DCAF8,KIAA0513,FBXL5,RAB39B,HIPK3,FEM1B,FCF1,SH3GLB1,KMT5B,ELAVL2,CERCAM,F3,MSANTD4,C15orf41,FAXC,SESN1,CRCP,CBX1,LUZP2,FUT10,GRB10,NR3C1,RBPJ,KCNB1,STMN1,MDM4,KCNK10,PFKFB3,PFKP,ZFYVE21,LRP12,SH3KBP1,PRKCB,SLC22A23,PXK,PEX2,RAB5B,CEP97,ATXN1,TMEM200C,RUFY2,FAM126B,SP4,TAF6,SATB2,NACC2,TPM4,RGMB,EMSY,ADAMTS9,ITM2C,WNK3" MicroRNA hsa-miR-30c-1-3p:Functional MTI Functional MTI miRTarbase 3.21E-23 1.80E-19 6.78E-23 6.25E-22 89 531 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,DDX3Y,SYNJ2,ISPD,SLC16A4,MYOM2,CHRNB2,EPS15L1,SUMF2,BTF3L4,MFSD4A,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,ABI2,PLEKHA1,MRNIP,MTSS1L,IGSF6,ANKFY1,PNMA2,TRAF3IP2,NCKAP1,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,DOCK7,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,FTO,SDK2,RETREG2,FAT3,PPARA,MTMR10,PTPRE,RAB5B,CEP97,PLEKHB2,SETD5,KLHDC8A,SOX6,MYO18A,CLSTN1,SLC1A2,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,AJAP1,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RFTN2,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,FTSJ1,TFIP11,EVI5,SNX27" MicroRNA hsa-miR-365:PITA hsa-miR-365:PITA_TOP PITA 3.46E-23 1.94E-19 7.30E-23 6.73E-22 48 168 "PTCHD1,SPOP,ANK3,CACHD1,API5,RGS20,ARRB2,DYNLL1,SYNJ1,NMT2,CREB5,SOCS5,DOCK4,HDAC4,TIAM2,G3BP2,EDNRA,EFNA3,RBM12,ETV1,EFEMP1,CAP2,MEGF10,RAPGEF4,ADAMTS6,KIF5C,KLC1,ARHGAP12,MARK1,MPP2,NFIX,PDYN,TRHDE,POLG,SNRK,PLEKHB2,REV3L,KIRREL1,SGK1,WDR37,SORCS3,ANKRD28,UNC5D,SATB2,HHIP,TLL2,SGK3,FMN2" MicroRNA hsa-miR-708:PITA hsa-miR-708:PITA_TOP PITA 3.53E-23 1.98E-19 7.45E-23 6.86E-22 46 154 "PDZD4,AMPH,ANK1,SEMA4G,CACNA1G,LDLRAD4,CABP7,FMNL3,DCLK1,CDH18,CNTFR,SH2B1,GDA,GAPVD1,SH3GLB1,EFNB3,EN2,EPHB1,FOXO3,SYT3,ZNF512,CHL1,SESN1,GPM6A,GRIA4,HNRNPK,MAT2A,NCAM1,NFE2L2,NNAT,OPHN1,HMGCLL1,TMEM260,RDX,ATXN1,SMARCC2,IGSF9B,SPTB,SYT11,SYN2,TRPS1,PRDM2,SNX27,WIPF2,KAT6A,JMJD1C" MicroRNA hsa-miR-3662:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.68E-23 2.06E-19 7.76E-23 7.15E-22 59 253 "FZD9,ZNF578,APP,CDC25B,SRSF11,TOGARAM2,SPATA2,CEP170,G3BP2,SRARP,MRVI1,ACSL4,MED12L,UBE2E3,SEMA4D,NPTN,CELF1,MSANTD4,SALL3,NCKAP1,MMADHC,RNPS1,TNRC6A,NUDT21,ZNF181,ZIC5,STMN1,MDM4,ZNF680,MYBPC1,MYO5A,NFIA,OPHN1,GPR137C,CCSER2,PSAT1,EPB41L4B,MAPK8,SH3TC2,RFX3,KLHL11,CLIP1,SEMA6D,SGK1,BTBD3,SLC6A8,TMCC1,SOX11,ITPRID2,SLC35G2,ZMAT3,NACC2,UGT8,MFF,JMJD1C,ZDHHC20,FXR1,NETO2,GAN" MicroRNA hsa-miR-30c-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.61E-23 2.59E-19 9.74E-23 8.97E-22 90 544 "XKR4,PLEKHH1,TXNDC16,PPFIA4,AQP6,CDC14B,DNAH17,DDX3Y,SYNJ2,ISPD,SLC16A4,MYOM2,CHRNB2,EPS15L1,SUMF2,BTF3L4,MFSD4A,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,DNAL1,SGSM2,DNAH9,SLC29A4,TMTC1,MRO,ABI2,PLEKHA1,MRNIP,MTSS1L,IGSF6,RACK1,ANKFY1,PNMA2,TRAF3IP2,NCKAP1,CRCP,TNRC6A,GLUL,GNG4,IRAK3,MIER3,IGF1,DOCK7,TJAP1,KCNK3,SMAD9,MATN3,PPM1L,SLC11A2,ZNF713,GPR137C,FTO,SDK2,RETREG2,FAT3,PPARA,MTMR10,PTPRE,RAB5B,CEP97,PLEKHB2,SETD5,KLHDC8A,SOX6,MYO18A,CLSTN1,SLC1A2,ATF7IP,ZKSCAN3,MCF2L2,ZSCAN29,AJAP1,FAM208A,SLC19A3,PCDHA6,ARL10,ERCC6L2,RFTN2,RPL7L1,PITPNB,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,SNX27" MicroRNA hsa-let-7i*:mirSVR_highEffct hsa-let-7i*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.77E-23 2.68E-19 1.01E-22 9.27E-22 46 155 "SEMA6A,ZFYVE28,CADPS,DST,CALB2,VSTM2A,LRBA,AHCTF1,ZNF521,ERC2,CTNND1,CCDC144A,ADGRV1,FOXG1,ST6GALNAC3,ABLIM2,PHYHIPL,STAG2,CNDP1,GRIA2,GRIA4,HTR2A,KCNN3,HECTD2,MOG,CNOT4,SNTG1,DPY19L2P2,SLC10A4,CDK14,NALCN,EXOSC10,TMEM260,GTDC1,MRAP2,ST6GALNAC6,SCN2A,STOX1,ADHFE1,DICER1,C5orf64,C9orf85,UGT8,CIAPIN1,WNK3,RTN4" MicroRNA hsa-miR-191*:mirSVR_highEffct hsa-miR-191*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.88E-23 2.74E-19 1.03E-22 9.48E-22 57 238 "ATP2B3,DST,ARHGEF7,KALRN,SMARCAL1,CHD1L,DZIP3,DCAF4,GAPVD1,MAML1,GSDME,RABGAP1L,CHRDL1,PHF20L1,SRRM1,WAC,FER,SEMA6C,SGIP1,GPD2,GPR17,RNF165,HMGB1,KCNJ3,KIF5A,KLC1,MYT1,DNHD1,NPPA,SLC11A2,OGG1,PDYN,MAPK8,PSMD13,OCIAD1,ZFHX4,MEG3,PPP4R3A,RCOR3,LIMCH1,FNBP1,KLHL7,SYN2,DDHD2,CAMTA1,ZEB1,WASHC4,ZFP91,TSN,AMOT,TOM1L2,RICTOR,UPF3A,PCBP4,HNRNPA3,PHTF2,ZNF248" MicroRNA "TCTGGAC,MIR-198:MSigDB" "TCTGGAC,MIR-198:MSigDB" MSigDB 5.47E-23 3.07E-19 1.15E-22 1.06E-21 34 81 "ARID1A,PCDH19,PHF12,BCL7A,BSN,CAPN3,NRXN1,STOML1,QKI,CNR1,SLC25A27,LETMD1,CREB5,NCOR2,SLITRK5,APH1A,JPH4,GLYR1,KDM2B,BTN2A1,TOX2,KCND1,MSR1,NNAT,PBX1,ATG16L1,FIGN,RIMKLA,ZNF821,POGZ,SMOC1,TCEA1,PUM2,NR2C2" MicroRNA hsa-miR-335-5p:TargetScan hsa-miR-335-5p TargetScan 5.92E-23 3.33E-19 1.25E-22 1.15E-21 54 215 "NCKAP5,ELFN2,CDK13,BCL2L2,BSN,CERS5,ARHGEF2,GPR37L1,RAB3C,NRXN1,CLOCK,OSBPL3,FAM131B,ARHGAP32,FAM107B,RBM12,PLEKHO1,ERBB4,CORO2B,HPCAL4,CAMKK2,GABRB1,GLYR1,GPR75,KDM2B,KAT7,GUCY1A2,NXPH2,KLF12,ITPKB,LSAMP,MAOB,FAT3,MAPK10,FITM2,CNNM2,APTX,PTPRB,ERI2,RPE,KDM4C,FAM168A,PSD3,ITGB3BP,RBFOX2,DOK6,RPRM,POLR3H,EVI5,PRDM10,RGS7BP,FZD3,NETO2,GAN" MicroRNA hsa-miR-551b:mirSVR_lowEffct hsa-miR-551b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 5.99E-23 3.36E-19 1.26E-22 1.16E-21 61 272 "KDM5D,CSMD2,DPP10,CACNA1B,CACNA1D,RUNX1T1,P2RX6,NEURL1,JAM2,PPT2,COL4A5,PNKD,APPL1,CENPL,MFAP3L,CCDC3,KBTBD11,HIPK3,PHF20L1,ABI2,GOLGA7,VPS13B,ERBB2,ERBB4,ANKMY1,FGFR1,DISC1,ADAM28,LNX1,CNDP1,FAAP20,DOCK7,SFXN5,MBP,ADAM11,MEIS1,SCG3,NUMA1,OGG1,ING3,PPP2R2B,RAD51D,GTDC1,ABCA11P,KCNIP3,COPZ1,FAM81A,SNRPN,KDM4B,ZC3H13,LHPP,CEP68,GSE1,ARHGEF9,TMEM136,ZFP91,ZIC3,RNF103,EPM2A,FBXO36,KLHDC1" MicroRNA "TAATGTG,MIR-323:MSigDB" "TAATGTG,MIR-323:MSigDB" MSigDB 6.30E-23 3.54E-19 1.33E-22 1.22E-21 45 149 "ARHGAP20,FAM135A,PKP4,NT5C3B,PPP4R4,SLC4A4,CLCN3,MAP4K4,TBPL1,CSNK1G3,FEM1B,EGR3,PTK2B,SPSB4,SUCO,ARFIP1,PPARGC1A,TNRC6A,GPM6A,ADAMTS6,ZHX1,KCNJ3,NFIX,PCDH9,ANKHD1,DPF2,REV3L,SEMA6D,SATB1,CPEB4,NKAIN2,LRRC4,SEPT3,FGD4,CAMTA1,ANO4,RPGRIP1L,CLASP1,TMOD1,TMPO,WBP2,NSD2,ZIC1,SMARCAD1,PAK5" MicroRNA hsa-miR-874:PITA hsa-miR-874:PITA_TOP PITA 6.30E-23 3.54E-19 1.33E-22 1.22E-21 45 149 "XKR4,DSCAML1,SLC12A5,SORCS1,DYNLL1,FMNL3,NMT2,CABP1,CNTNAP2,RHOBTB1,DTNB,EGR3,EML1,PPP1R1B,MEGF11,GLDC,C5orf24,INPP5B,ARHGAP12,MAT2A,MXI1,NRCAM,POU3F2,PPP5C,PLEKHB2,ATG16L1,RAP1GAP,OXR1,ATXN1,PPP4R3A,CPEB4,RIMS1,SPTB,ST5,MAPK8IP3,AJAP1,ADGRL3,TBL1X,SATB2,PSD3,THRA,NR2C2,TRPS1,SNX27,MSRB3" MicroRNA hsa-miR-6845-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.50E-23 3.65E-19 1.37E-22 1.26E-21 60 264 "PWWP2A,MTA3,SEMA7A,ARHGDIA,PTCH2,ATP1A3,ATP2B1,BCL2L2,NIPA1,LDLRAD4,RUNX1T1,FMNL3,CDH8,CBARP,RAB3C,CSNK1G3,PITPNM3,UBXN2A,CYBB,GAPVD1,SMG7,EMX2,SLC43A2,TUBB4A,GALC,DISC1,GATM,FAXC,GJB1,GPT2,C2CD4C,KCNJ11,LSAMP,NFIX,NFYA,PALM,EPN1,SNRK,ATXN7,ASIC4,FAM214B,ZFP1,ZNF667,ZNF415,CLUAP1,UNC5B,LRRC4,MPRIP,DIP2A,USP22,SZT2,CRTC1,SMUG1,TMPRSS5,ZNF23,ZNF138,PMEPA1,STMN4,HNRNPA3,JPH3" MicroRNA hsa-miR-4739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.22E-23 4.05E-19 1.52E-22 1.40E-21 63 290 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,GNG3,ZNF496,SLC6A17,MAG,MAT2A,NBL1,NFIX,TBC1D25,OGDH,CDK14,RETREG2,POLR2F,PTPA,SH3TC2,MORC4,MYH14,RTKN,HES6,CLSTN1,RPH3A,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,HHIP,THRA,NACC2,TPM3,PPIL6,TMPRSS5,TUBB2A,BCL2L13,TSPAN11,ZNF70,NAV2,PARP11,TMEM63C,FAM198A" MicroRNA hsa-miR-296-3p:PITA hsa-miR-296-3p:PITA_TOP PITA 8.41E-23 4.72E-19 1.77E-22 1.63E-21 36 93 "FMNL2,ERMN,CADPS,ATP2A2,JAZF1,FOXN3,SOCS6,NRXN3,CREB5,DCAF8,JAKMIP2,DLG2,CALN1,PAN3,AGAP2,STAG2,TCERG1,GRM3,KLF12,KITLG,SERPINE2,PLP1,ANKRD16,STRN3,PTCH1,RBBP6,MSANTD2,FBXW7,SEMA6D,ERC1,POGZ,NKAIN2,SYN1,TCF7,TCF12,TBC1D15" MicroRNA hsa-miR-652:mirSVR_lowEffct hsa-miR-652:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.00E-22 5.62E-19 2.10E-22 1.94E-21 66 318 "BEND6,SUGT1P4-STRA6LP-CCDC180,PKP4,KIAA1614,ADGRB2,NRP2,SLC16A4,LRBA,ARHGEF6,CDC42BPB,NCOR2,ARHGEF10,SACS,TOM1,SGK2,ELN,DCTN4,SEZ6,EFS,PIPOX,DLC1,GABRB3,GALC,RAB40B,GNAS,LINC00839,FAAP20,KCNJ11,MAN2A2,MATN2,MATN3,TM6SF1,MPP2,FXYD6,VWA2,LOC100128398,PDPK1,PRRX1,PRKCZ,PLEKHB2,FAM66C,ZNF793,ATG16L1,OXR1,SEC61A2,SCN8A,ITSN1,FERMT1,ST3GAL3,FAM81A,RPH3A,SLC11A1,MTERF2,SLIT1,ZFP1,RCOR3,MYO16,KIF21B,KDM4C,TCF12,TTTY15,SLAIN1,VLDLR,ZFAND5,MAP3K12,JPH3" MicroRNA hsa-miR-3186-3p:mirSVR_lowEffct hsa-miR-3186-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.06E-22 5.96E-19 2.23E-22 2.05E-21 48 172 "ARID1A,FZD9,AP2A2,AMPH,APBB1,RGS20,TRIM41,ASIC3,CHRNB2,FAM149A,BTF3L4,IGDCC3,PITPNC1,ZNF582-AS1,DLG3,SLC29A4,DNM1L,ANKRD13B,SPEG,BAIAP2,FHL1,TPK1,DACH2,ADGRA1,ADAMTS13,ZBTB49,CPT1C,SYT9,GIT1,NNAT,WBP1L,IQSEC3,RNF220,DRAXIN,ITSN1,ST3GAL3,SLC6A1,MAST1,CAMTA2,SSPO,PJA1,WDR7,VWCE,DICER1-AS1,C9orf85,CIAPIN1,C12orf4,DOCK8" MicroRNA hsa-miR-518e:mirSVR_highEffct hsa-miR-518e:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.06E-22 5.96E-19 2.23E-22 2.05E-21 48 172 "TTYH1,ZNF608,STK33,PCDHGB4,BARD1,JAZF1,SGCE,CFAP410,CCPG1,ARHGAP22,COL9A1,ZNF521,CSNK1G3,FHL1,IP6K2,TACC2,NSG2,MEGF11,SULT1C4,SYTL4,KITLG,PC,PCDHGC3,BEST3,PPP3CB,SON,KDM4C,TROVE2,KLHL7,MLC1,PLCB1,MCF2L,AGTPBP1,WSCD1,PCDHGC5,PCDHGB7,PCDHGB6,PCDHGB2,PCDHGB1,PCDHGA11,PCDHGA10,PCDHGA9,PCDHGA6,PCDHGA4,PCDHGA3,PCDHGA2,PCDHGA1,RIMBP2" MicroRNA hsa-miR-505-3p.1:TargetScan hsa-miR-505-3p.1 TargetScan 1.20E-22 6.75E-19 2.52E-22 2.33E-21 54 218 "ABAT,ACTN2,HECW2,APBB2,MIER1,PDXK,CACNA1E,CACNB4,CANX,MAP7,C1orf52,NUMBL,FOXN3,MAGED1,NRG2,CCDC144A,KIAA0408,CPEB2,DNM1L,ANKFY1,MSANTD4,GABRB1,GABRG1,ATP8A2,CYP46A1,GLYR1,FUT10,HMGB1,NEGR1,C2orf72,IL6ST,KIT,LRP1B,MEIS1,MEIS2,MYCN,HNRNPM,NOVA1,OPA1,SCHIP1,CNNM2,CEP97,RFX4,KCNIP2,FAM192A,EPN2,EPC1,FAM126B,MYT1L,ELOVL4,C3orf70,CBX5,RFTN2,CADM1" MicroRNA hsa-miR-1291:PITA hsa-miR-1291:PITA_TOP PITA 1.26E-22 7.10E-19 2.65E-22 2.44E-21 42 131 "MTUS1,LRFN1,USP37,CADM3,ADGRB1,DCAF5,HAP1,SYT6,SH2B1,PHYHIP,DBN1,C2CD2L,DYNC1I1,TNK2,AGAP3,SGIP1,BRSK1,BRPF3,GRIN1,ATXN2L,ELOVL5,LRRC75A,KCNN3,MEF2C,MDGA1,CAMKV,SDK2,MED1,TMEM260,PTPRD,LGR4,MAGI3,FAM214B,SLC8A1,TSPYL2,EXOC7,TAL1,FBXW11,TIAM1,RELL2,RBFOX2,VANGL2" MicroRNA hsa-miR-4282:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-22 7.23E-19 2.70E-22 2.49E-21 63 293 "RALGAPA1,SDE2,XKR4,SPOP,SFMBT2,ATP2B1,ZNF582,CACNG1,CDC27,CCPG1,CLCN3,QKI,FEZ2,ATRNL1,HDAC4,DBN1,ELMSAN1,CPEB2,EDN3,MRNIP,C8orf37,DCTN4,ENPP6,SRRM1,NPTN,COPS8,NR3C1,KIF3A,FAM107A,CHIC1,NFYA,NRCAM,GPR137C,PDE4D,PDZRN4,KANSL1,MAPK8,UHRF1BP1,PTPRG,ZYG11B,REV3L,GTDC1,KLHL11,RORB,UEVLD,TRA2B,MAGI3,EPN2,SLC8A1,EPC1,SON,SP4,SRPK2,TROVE2,NECAB1,DICER1,ZMAT3,TPD52,TPM3,FMN2,ZXDA,PRDM10,KCNAB1" MicroRNA hsa-miR-711:mirSVR_highEffct hsa-miR-711:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.30E-22 7.30E-19 2.73E-22 2.51E-21 74 393 "KCNH8,ACLY,SLITRK1,AK2,ALK,LRCH2,FGD2,ZBTB10,TTLL9,CACNA1D,LURAP1,CARS,LRBA,ARHGAP33,COL4A5,CNRIP1,ANKRD44,CTNND1,GPSM1,ECE2,CYBB,DCC,HP1BP3,DDX46,AASDH,DMTN,LRRC17,FGF14,TMEM164,B3GAT1,RAB30,ZNF638,CECR2,PCLO,GRIA2,GRIA4,ZNF496,GUCY1A2,HTR5A,DOCK7,IL11RA,KCNN2,PIK3AP1,NOVA1,PPP2R2B,PTPA,SIDT1,PIGG,PEX5,CEP97,MORC4,RNF220,ELP2,TCP11L1,TRIM46,ITSN1,CNKSR2,RUFY2,EFHD1,SNRPN,GANAB,SYT1,CAMTA1,WWC1,SPX,TMOD1,SYNPO2,PRMT8,AMACR,UGT8,ATP6V0E2,POLR3H,GDPD5,TMEM163" MicroRNA hsa-miR-887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-22 7.62E-19 2.84E-22 2.62E-21 82 471 "XKR4,PLEKHH1,TXNDC16,AQP6,DNAH17,SYNJ2,ISPD,SLC16A4,MYOM2,SUMF2,MFSD4A,CLOCK,PPP1R16B,UBXN2A,CTNND1,USP6NL,MYADM,GAPVD1,DNAL1,DNAH9,SLC29A4,TMTC1,MRO,ABI2,PLEKHA1,MRNIP,IGSF6,ANKFY1,PNMA2,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,GRIK2,IRAK3,MIER3,IGF1,DOCK7,TJAP1,SMAD9,MATN3,MDM4,PPM1L,SLC11A2,OCRL,ZNF713,FTO,RETREG2,FAT3,CNTLN,MTMR10,RAB5B,CEP97,PLEKHB2,KLHDC8A,SOX6,GALNT10,MYO18A,CLSTN1,SLC1A2,SLC6A9,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ZFP91,ERCC6L2,RFTN2,RPL7L1,ZNF708,ZNF17,ZNF70,DPYSL5,TFIP11,EVI5,SIGLEC10,SNX27,ZDHHC20" MicroRNA hsa-miR-574-5p:PITA hsa-miR-574-5p:PITA_TOP PITA 1.40E-22 7.86E-19 2.93E-22 2.70E-21 38 106 "ANK1,ATP1A1,ADGRB2,PTBP2,FOXN3,CNR1,CTNND2,G3BP2,NRN1,FOXO3,GAB1,AHCYL1,ZHX1,NEGR1,HSF2,MARK1,ERICH3,MDGA1,NCAM1,NEUROD2,SEMA5B,TNPO2,CEP41,FNIP1,ARX,SLC4A3,SNAP25,SOX2,SP4,ANO4,HHIP,RIMBP2,FLRT2,NSD2,SH3GLB2,PRDM8,ADAMTS10,PIANP" MicroRNA hsa-miR-507:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-22 8.26E-19 3.08E-22 2.84E-21 50 188 "ARID1A,KCTD16,SEMA6A,BACH1,BCL7A,BID,JAZF1,CALM1,COL9A2,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,GUCD1,ST8SIA3,EDN1,STARD3NL,SLC43A2,WAC,ACSL4,SCML2,FER,HBS1L,PRRC2B,BACH2,HMGB1,RBPJ,LIMS1,SESN3,P2RY1,PLIN1,STRN3,MAPK8,ACSS3,NWD1,ACER3,KCNIP3,SATB1,SLC30A10,PEX26,LRRC55,SLC8A1,EMC1,UNC5D,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-557:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-22 8.26E-19 3.08E-22 2.84E-21 50 188 "ARID1A,KCTD16,SEMA6A,BACH1,BCL7A,BID,JAZF1,CALM1,COL9A2,CLOCK,VCAN,USP6NL,KIAA0408,PITPNC1,TIAM2,GUCD1,ST8SIA3,EDN1,STARD3NL,SLC43A2,WAC,ACSL4,SCML2,FER,HBS1L,PRRC2B,BACH2,HMGB1,RBPJ,LIMS1,SESN3,P2RY1,PLIN1,STRN3,MAPK8,ACSS3,NWD1,ACER3,KCNIP3,SATB1,SLC30A10,PEX26,LRRC55,SLC8A1,EMC1,UNC5D,UBTF,ZNF154,REEP1,HNRNPA3" MicroRNA hsa-miR-331-3p:PITA hsa-miR-331-3p:PITA_TOP PITA 1.51E-22 8.48E-19 3.16E-22 2.91E-21 41 125 "DPF1,CSMD2,XKR4,UNC5A,TRMT9B,SEMA4G,TAOK2,MYRIP,RIMS4,ELMSAN1,PHC2,EGR3,ELN,ANKRD13B,NRN1,PTK2B,SCML2,NBEA,TNRC6A,PLPP7,ATOH8,CAMK2N2,MEIS1,MEIS2,MSI1,MDGA1,NEUROD2,CLDN11,PTPRD,C1orf109,RAB5B,RIC8B,WLS,FAM214B,PKNOX2,YPEL4,FAM126B,STAC2,ADGRL3,POLR3H,PRDM8" MicroRNA hsa-miR-7111-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-22 8.52E-19 3.18E-22 2.93E-21 54 219 "SERPINA3,SLC25A25,ADCY6,TNRC6C,APP,LDLRAD4,RUNX1T1,LRRFIP1,SLC22A6,CLTC,TMEM184B,IGLON5,PITPNM3,PLCXD3,KIAA0408,IP6K1,SMG7,TMCC2,DPYSL2,ANKMY1,REEP2,SCML2,AMOTL2,HHIPL1,ZNF638,GRIK3,GRM8,PTGDR2,KCNN3,SYTL4,MBNL1,GDAP1L1,POLG,POU6F1,KANSL1,ZNF844,C12orf49,ELP2,ASIC4,ZFP30,SLC6A8,SMARCE1,ERC1,SEPT8,ACSBG1,VPS13A,TMEM178B,CRTC1,TGFBR3,RBFOX2,UGT8,AMZ1,DPYSL5,FRMD6" MicroRNA hsa-miR-1973:mirSVR_lowEffct hsa-miR-1973:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.61E-22 9.02E-19 3.36E-22 3.09E-21 59 260 "ABR,ACTN1,KLHL32,RNF157,AXIN2,ESYT2,ADGRF5,KCNT1,NCOA1,CADM3,BMP7,ARHGEF2,ZNF521,ST18,FGFR1OP2,MATR3,DBN1,CDON,DNM1L,EPHA5,ZNF589,PRKAG2,FOXM1,ZNF512,HBS1L,DISC1,ATP8A2,OLFM3,KIF2A,ZFYVE27,IL17D,MSR1,MYT1,PCSK5,PDPK1,PFKP,CDK14,PLPPR1,PTPRG,ROBO2,PCMTD2,ITSN1,FNDC3A,ZNF365,RCOR3,SOX2,DBNDD2,LMO3,SSTR2,CEP68,CRB1,GZF1,RPRM,FLRT1,PRTFDC1,PRDM8,URM1,PHTF2,FXR1" MicroRNA hsa-miR-4713-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-22 9.21E-19 3.43E-22 3.16E-21 51 196 "PWWP2A,PTCHD1,PHF12,ARSE,ASPA,ATP2B1,ZNF582,BACH1,FOXK1,CBS,NEURL1,CDH8,PITPNM3,SPATA2,PHF20L1,EPB41L1,TUBB4A,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,NCKAP1,FAXC,ZNF638,KIAA1958,AP4S1,PADI2,KCNQ3,STMN1,LSAMP,MBNL1,NFYA,ZDHHC22,PAK3,GNG2,SDK2,ZNF844,SLIT1,ZFP1,ZNF415,ZCCHC24,ACSL6,SMUG1,RUNDC3B,SSBP2,TSPAN11,ZNF781,ZNF138,DPYSL5,URM1,GAN" MicroRNA hsa-miR-4311:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-22 9.21E-19 3.43E-22 3.16E-21 51 196 "ADCYAP1R1,TRMT9B,CDC42BPA,APP,CALM1,CDC27,AKAP6,TM9SF4,SPATA2,PLEKHM1,FAM107B,CHRDL1,ZNF391,WAC,SGIP1,SARAF,HRASLS5,SYT17,WASF3,SRCAP,PPARGC1A,RNPS1,DCLK2,CECR2,GRB10,PTPRT,SYNPO,PLD5,MAG,MEIS1,NFIA,CNOT4,GPR137C,ZNF827,GPR173,PDZRN4,PTPRN2,CEP97,MORC4,CCDC88A,SON,TAB2,SLC19A3,SLC44A1,KAT6B,TPD52,TUBB2A,WRN,ZIC2,SIGLEC10,ZNF248" MicroRNA hsa-miR-496.2:TargetScan hsa-miR-496.2 TargetScan 1.76E-22 9.91E-19 3.69E-22 3.40E-21 42 132 "ERMN,DPP10,MIER1,ATP2B2,BACH1,REPS2,CNTNAP2,PYGO1,ELMSAN1,DNAJB6,EPB41L1,EPB41L2,SEC23B,MSANTD4,GAB1,GBX2,GFRA1,GPR26,GRID1,GRIK2,FAM19A2,LRRTM3,PAXBP1,LRP1B,PCSK1,PDE4D,PFKFB3,GPSM2,RAD51D,RGS4,AP1AR,CSRNP3,SEC14L1,HSPA4L,ITSN1,DHX30,LMO3,LARP4,ITGB3BP,NACC2,CBX5,DAAM2" MicroRNA hsa-miR-4756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-22 9.94E-19 3.70E-22 3.41E-21 62 286 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,GNG3,ZNF496,SLC6A17,MAG,MAT2A,NBL1,NFIX,TBC1D25,OGDH,CDK14,RETREG2,POLR2F,PTPA,SH3TC2,MORC4,MYH14,RTKN,HES6,CLSTN1,RPH3A,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,HHIP,THRA,NACC2,TPM3,PPIL6,TMPRSS5,TUBB2A,BCL2L13,TSPAN11,ZNF70,NAV2,PARP11,FAM198A" MicroRNA hsa-miR-1225-3p:mirSVR_highEffct hsa-miR-1225-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.77E-22 9.94E-19 3.70E-22 3.41E-21 62 286 "KCNH8,C1QTNF3,APAF1,MAGEE2,SPTBN4,NAE1,SCAPER,RUNX1T1,CBR1,CACNA2D2,PPT2,ABCG1,SEC24C,PDE4DIP,ECE2,CYBB,DNM1,TOM1,SGK2,ERBB2,TLR7,ECSIT,FHL1,NELFCD,AKAP3,TMEM107,GABBR1,GAD1,DISC1,GPR162,TCERG1,MCHR1,CLASRP,PSIP1,C1orf94,MSL1,GPR62,ZFYVE27,SYT9,CCDC80,NEFM,NOVA1,SNTG1,PCDH9,PDE1B,PTN,SLC6A15,ARHGEF10L,RNF220,CCDC25,RORB,MEG3,ITSN1,ST3GAL3,SLC15A2,SLIT1,TSPYL2,FGD4,WDR7,USP32P1,BEX4,NDRG4" MicroRNA hsa-miR-4722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-22 1.00E-18 3.72E-22 3.43E-21 81 463 "AS3MT,RNF157,ADD1,ESYT2,SORCS2,ABCD2,CDC14B,SLC7A14,ARSE,SLC4A4,ALDH7A1,LDLRAD4,QKI,CREM,RNF14,HINFP,CSNK1E,KIAA0408,DNAL1,RABGAP1L,KBTBD11,EXOG,CD99L2,CNNM1,MRNIP,RGS17,EMX2,PLEKHO1,SLC43A2,FKTN,FDFT1,VTI1B,FOXO3,PDLIM5,TMEM151A,CRCP,CNDP1,GRK4,RAPGEF1,KIF3A,RNF165,HMGB1,ZDHHC15,EID2B,IL6R,KCNQ3,NCOA7,LSAMP,MAN2A2,ALDH1L2,NOVA2,PBX1,CAMKV,MTRF1L,TNPO2,APTX,TMEM231,ZNF844,GTDC1,PGBD4,RXRA,SCN2B,ZFP30,PEX26,SLIT1,ZNF667,CLUAP1,ARHGAP26,AGTPBP1,SIN3B,ZNF106,GALNT17,ARL10,ERCC6L2,RPL7L1,CFAP298,AGMO,ZNF70,LMAN2L,WIPF2,MPPE1" MicroRNA hsa-miR-1287:PITA hsa-miR-1287:PITA_TOP PITA 1.94E-22 1.09E-18 4.05E-22 3.73E-21 39 113 "XKR4,SLC7A14,NOL4,CA8,CACNB4,FMNL3,ZMYM4,CHN1,QKI,ZNF385A,PREPL,LYPD1,DLG4,MBNL2,SPEG,GABRB3,GPM6A,GRIA4,PSIP1,KIAA1755,PLD5,SYT9,CNOT4,PMP22,MAPK10,OCIAD1,RIC8B,SH3GL2,FBXO11,SLC8A1,SOX11,ERC1,TMOD1,TPM3,HEPACAM,ZFAND5,NAV3,PAK5,KAT6A" MicroRNA hsa-miR-580-3p:Functional MTI Functional MTI miRTarbase 1.96E-22 1.10E-18 4.08E-22 3.76E-21 43 139 "RNF157,AK2,SEMA7A,TNRC6C,MIER1,BACH1,AKAP5,TBPL1,CLOCK,RNF14,ST18,RUBCN,TOMM20,CTIF,GUCD1,SRARP,AMOTL2,PCYOX1,FAM49B,HRASLS5,CAB39,GPR75,HTR2A,ZNF678,LAMA2,MBNL1,XRRA1,TNPO2,PRKAB2,SLC25A36,SETD5,ARMH4,ACER3,FAM161B,FNBP1,ZNF621,POGZ,ACSL6,ZMAT3,TPD52L2,BCL2L13,MTCH1,WIPF2" MicroRNA hsa-miR-6880-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.03E-22 1.14E-18 4.23E-22 3.90E-21 65 313 "ABCF1,RNF157,PNMA8B,HACE1,TAOK1,PDZD4,PHF12,PTBP2,CBS,CFL2,NRXN3,BTF3L4,CSNK1E,GAPVD1,KIAA0513,SIRPA,DNAL1,HP1BP3,SGSM2,GNE,DUSP9,DYRK1A,MRO,EN2,MTSS1L,MRPL10,FGFR1,NEURL4,MTHFD2,CSDC2,GLYR1,PRRC2B,CECR2,HMX1,IGF1,PPM1L,MKLN1,MXI1,PABPC1L2A,PKM,PLCD1,PLEC,FXYD1,PLXNB1,PACSIN1,TNPO2,FAT3,NCR3LG1,MTMR10,PGBD4,FAM161B,NCBP3,STUM,PEG10,DBNDD2,CDK19,ASTN2,AGTPBP1,HIF3A,NACC2,LAT2,ZNF17,SLC38A1,EVI5,PARP11" MicroRNA hsa-miR-23b-3p:Functional MTI Functional MTI miRTarbase 2.06E-22 1.16E-18 4.29E-22 3.95E-21 66 322 "ABCF1,ADD3,USP31,NLGN4X,SORCS2,ZNF578,ATP1A1,BCS1L,SOCS6,CLTA,HAPLN1,VCAN,DOCK4,TMEM170A,G3BP2,PDCD6IP,FSD1L,EN2,DMTN,PTK2B,RACK1,CELF1,AP4B1,MPP6,ARFIP1,ADAM28,TNRC6A,HNRNPK,ZIC5,JAK1,MAP4,BLOC1S2,SNTG1,PIK3R1,ZNF426,CRLS1,KANSL1,PRKACB,ZIK1,RAB5B,ACSS3,BSDC1,SLC6A15,CYB561D1,PCMTD2,SEMA6D,SBF1,FNIP1,CPEB3,ATF7IP,CLUAP1,EMC1,TAB2,ERBIN,GANAB,DNMBP,ZEB1,NSD1,SIRT1,TPM3,RPL7L1,XPO1,ZNF138,DHX33,CSDE1,JMJD1C" MicroRNA hsa-miR-432:PITA hsa-miR-432:PITA_TOP PITA 2.08E-22 1.17E-18 4.32E-22 3.98E-21 46 160 "UNC5A,PWWP2A,PTCHD1,EIF4G3,VSTM2A,FOXN3,NRXN3,SLC35F1,SOCS5,ARHGEF4,PITPNC1,ALKBH8,RHOBTB1,CPEB2,ABI1,DNAJB6,OPTN,EFNB3,GOLGA7,EPB41,ERBB4,GHR,GK,TCERG1,EML4,PCLO,GRIA2,FAM222A,CHIC1,NEUROD1,PDE1B,PMP22,STRN3,TMEM260,RASGRF1,FBXW7,SCP2,CCDC88A,FAM126B,SOX2,RBM26,SYN1,AHCYL2,TRPC3,TUB,NSD2" MicroRNA hsa-miR-621:PITA hsa-miR-621:PITA_TOP PITA 2.09E-22 1.17E-18 4.35E-22 4.00E-21 37 101 "ACTN1,CCDC85A,NLGN4X,PCDH19,ANK3,SYT6,DCLK1,CFL2,FOXN3,NRXN1,HP1BP3,ANKRD13B,AKAP3,CAB39,DNER,GLS,GPD2,ZHX1,MIER3,MEF2C,KITLG,NEXMIF,ZC3H12B,GPR85,PFKFB3,CAMKV,PTPRD,RDX,ZFHX4,ELMOD1,NLGN4Y,WDR37,SLC12A2,HECW1,FGD4,ZNF346,PAK5" MicroRNA hsa-miR-299-5p:TargetScan hsa-miR-299-5p TargetScan 2.10E-22 1.18E-18 4.38E-22 4.03E-21 51 197 "ABR,BRAP,RNF150,MIER1,CASK,CCAR2,ATP2B2,MTMR9,DST,BTRC,NSL1,CLOCK,CS,HDAC4,CTIF,DLG3,CPEB2,FAM135B,EDNRB,HIPK3,PLXNC1,ELN,DCTN4,IQCG,IQGAP2,CECR2,RASSF8,C9orf129,RBPJ,KCNC2,MAT2A,HCN1,PCDH8,PCSK2,CCSER2,PROX1,GTDC1,RFX5,RNF220,ROBO1,RORB,RIMKLA,SCN2A,KDM4B,DDHD2,EXOC7,NSD1,PUM2,NR2C2,NAV3,MARCH8" MicroRNA hsa-miR-3180-3p:mirSVR_highEffct hsa-miR-3180-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.13E-22 1.20E-18 4.43E-22 4.08E-21 41 126 "SLITRK1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,ZSCAN18,SEC11C,DDR1,RUNX1T1,INA,DLGAP3,KIAA1549L,CLTA,CABP1,SLITRK5,CYBB,GTF2IRD2,PSD2,FAM107A,MEIS1,NKX2-2,NPTX2,ZNF827,NALCN,EXOSC10,VSTM2L,RFX4,RNF220,ST3GAL3,LGI3,SLC22A4,SMARCC2,TNIK,KAZN,PRRT1,FNDC5,NSD2,ATP6V0E2,ANKS1B,DHX33,CASC15,ADAMTS10,JPH3" MicroRNA hsa-miR-1321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-22 1.21E-18 4.47E-22 4.12E-21 62 287 "ELFN2,RNF157,HACE1,SORCS2,AK2,DDR1,LETMD1,NCOR2,RGS6,IPCEF1,PITPNM3,IP6K1,SEC16A,CHRDL1,SLC29A4,DUSP9,APH1A,SCML2,ANKFY1,GLYR1,STARD3,GNG3,ZNF496,SLC6A17,MAG,MAT2A,NBL1,NFIX,TBC1D25,OGDH,CDK14,RETREG2,POLR2F,PTPA,SH3TC2,MORC4,MYH14,RTKN,HES6,CLSTN1,RPH3A,TRIM67,SP2,IQSEC2,DDN,NEK4,STX1A,CLASP1,ZNF34,HHIP,THRA,NACC2,TPM3,PPIL6,TMPRSS5,TUBB2A,BCL2L13,TSPAN11,ZNF70,NAV2,PARP11,FAM198A" MicroRNA hsa-miR-4287:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-22 1.24E-18 4.59E-22 4.23E-21 60 270 "FAM43B,XKR4,ADCY5,ADCY6,MTA3,AK2,OGT,SEMA4G,ARSE,BACH1,CCNT1,CDH8,SLC22A6,QKI,LRIG1,PITPNM3,PLCXD3,CYBB,SPATA2,SMG7,EMX2,SLC43A2,SRARP,TACC2,TMEM151A,DKK3,SRRM4,FAXC,GJB1,ZNF638,RAPGEF1,GRID1,RFFL,GPR45,BACH2,MIER3,TLX1,SHISA6,KCNQ3,LSAMP,MBNL1,MDFI,MYO5A,GPR137C,ZDHHC22,MTMR10,PTPRG,RAB5B,GTDC1,ATXN7,CLUAP1,LRRC4,DIP2A,TMEM178B,IQCE,RUNDC3B,ZBTB16,TMEM198,RNF146,GAN" MicroRNA hsa-miR-6727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-22 1.33E-18 4.92E-22 4.53E-21 81 465 "AS3MT,RNF157,ADD1,ESYT2,SORCS2,ABCD2,CDC14B,SLC7A14,ARSE,SLC4A4,ALDH7A1,LDLRAD4,QKI,CREM,RNF14,HINFP,CSNK1E,KIAA0408,DNAL1,RABGAP1L,KBTBD11,EXOG,CD99L2,CNNM1,MRNIP,RGS17,EMX2,PLEKHO1,SLC43A2,FKTN,FDFT1,VTI1B,FOXO3,PDLIM5,TMEM151A,CRCP,CNDP1,GRK4,RAPGEF1,KIF3A,RNF165,HMGB1,ZDHHC15,EID2B,IL6R,KCNQ3,NCOA7,LSAMP,MAN2A2,ALDH1L2,NOVA2,PBX1,CAMKV,MTRF1L,TNPO2,APTX,TMEM231,ZNF844,GTDC1,PGBD4,RXRA,SCN2B,ZFP30,PEX26,SLIT1,ZNF667,CLUAP1,ARHGAP26,AGTPBP1,SIN3B,ZNF106,GALNT17,ARL10,ERCC6L2,RPL7L1,CFAP298,AGMO,ZNF70,LMAN2L,WIPF2,MPPE1" MicroRNA hsa-miR-5196-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-22 1.33E-18 4.93E-22 4.54E-21 64 305 "ELFN2,TRMT9B,ARHGDIA,ARRB2,TTLL9,BCL7A,FOXK1,MYOM2,ZNF385A,CRY2,RGS6,PPP1R16B,PLEKHM1,APH1A,MRO,ASB3,ZMYND11,MTHFD2,GFER,TNRC6A,LILRA2,RAPGEF1,GSN,NXPH3,TNFAIP8L3,SHISA6,C5orf24,MAT2A,PABPC1L2A,NFIX,OLR1,PDE3A,CDK14,PKM,KCTD15,NLE1,FXYD1,TNPO2,IQSEC3,PRRT2,ERI2,SETD5,MYH14,SEMA6D,SBF1,DRAXIN,SHMT2,PEX26,SLC6A9,WDTC1,MPRIP,AHCYL2,NACC2,ASXL3,BHLHB9,TPD52L2,TPM3,WBP2,TUBB2A,INTS3,URM1,ITM2C,WNK2,ZDHHC20" MicroRNA hsa-miR-4747-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-22 1.33E-18 4.93E-22 4.54E-21 64 305 "ELFN2,TRMT9B,ARHGDIA,ARRB2,TTLL9,BCL7A,FOXK1,MYOM2,ZNF385A,CRY2,RGS6,PPP1R16B,PLEKHM1,APH1A,MRO,ASB3,ZMYND11,MTHFD2,GFER,TNRC6A,LILRA2,RAPGEF1,GSN,NXPH3,TNFAIP8L3,SHISA6,C5orf24,MAT2A,PABPC1L2A,NFIX,OLR1,PDE3A,CDK14,PKM,KCTD15,NLE1,FXYD1,TNPO2,IQSEC3,PRRT2,ERI2,SETD5,MYH14,SEMA6D,SBF1,DRAXIN,SHMT2,PEX26,SLC6A9,WDTC1,MPRIP,AHCYL2,NACC2,ASXL3,BHLHB9,TPD52L2,TPM3,WBP2,TUBB2A,INTS3,URM1,ITM2C,WNK2,ZDHHC20" MicroRNA hsa-let-7f-5p:Functional MTI Functional MTI miRTarbase 2.44E-22 1.37E-18 5.06E-22 4.66E-21 74 397 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,CAPRIN2,ATP2A2,ALDH7A1,BACH1,CALM1,FMNL3,USP2,CNOT8,ARMC8,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ATL1,ANKRD46,EIF4G2,PLEKHO1,MTSS1L,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,GALC,SALL3,DISC1,GATM,COPS8,MSL3,GLUL,POLL,FUT10,RABL2A,ATXN2L,IL6R,KPNA5,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,KLK6,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,TAB2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,TGFBR3,CBX5,RBFOX2,TUBB2A,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-552:PITA hsa-miR-552:PITA_TOP PITA 2.45E-22 1.38E-18 5.09E-22 4.69E-21 50 190 "SPOP,API5,SYNJ1,LDLRAD4,CACNA1D,FMNL3,DGKI,DLGAP1,DLGAP3,QKI,BTF3L4,DCC,HP1BP3,ZC3H11A,POM121,CELSR3,EMX2,MRVI1,USP21,NPTN,INSM2,PRRC2B,ATF7,INPP5B,KIF5C,NEXMIF,NF1,NOVA1,NPTX1,OPCML,PACSIN1,POU3F2,MAPK10,SNRK,RAB5B,SGK1,FNDC3A,NLGN1,SLC8A3,LRRC4,GANAB,SYT1,ATP11A,CAMTA1,KIAA0930,WDR7,TRPS1,AMOT,VLDLR,WIPF2" MicroRNA hsa-miR-346:TargetScan hsa-miR-346 TargetScan 2.81E-22 1.58E-18 5.84E-22 5.38E-21 44 147 "PTCHD1,GOLGA7B,PDZD4,FAM131A,LRRC4C,CADM3,MTMR3,CACNA1I,MMD2,NRG2,PPP1R16B,RIMS2,ECE2,CCDC144A,LIN54,KLHL3,CALN1,EPB41L1,NCKAP1,KIAA1958,PRRC2B,RAPGEF1,GRIN1,RNF165,PTPN5,MFSD2A,C2orf72,KIF5C,NCOA7,MBNL1,MYO5A,NODAL,PURG,RDX,CYB561D1,ATP8B4,RIMKLA,ARHGEF40,PEG10,KIF1B,NCDN,AJAP1,NACC2,PPIL6" MicroRNA hsa-miR-3150b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-22 1.69E-18 6.22E-22 5.73E-21 55 230 "CPNE2,ARID1A,RNF157,ADD2,CASKIN1,PHF12,APBB2,CACNA1B,HAP1,METTL6,ARHGEF2,CRMP1,MICAL2,SLITRK5,CTIF,SEC16A,DNM2,EIF4G1,ING4,BSCL2,EIF1,EN2,EPB41L1,MRVI1,AFF2,PDLIM5,CELF1,SRCAP,PRRC2B,ZBTB45,IDH3A,METTL21A,KCND1,MPP2,PABPC1L2A,PFKFB3,SPATA6,TNPO2,BDNF-AS,SH3TC2,NCBP3,HES6,RPH3A,SLC8A1,TRIM67,WDTC1,UNC5B,PEG10,CAMTA2,ASTN2,PSD3,ZFP91,TUBB2A,SF1,ZNF70" MicroRNA hsa-miR-6734-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-22 1.70E-18 6.27E-22 5.78E-21 54 222 "AS3MT,AK2,ASGR1,DDR1,LURAP1,LRRFIP1,NUMBL,B4GALT6,SLC22A6,CREB5,CRY2,PDE4DIP,PLCXD3,CYBB,RIMS3,G3BP2,TMCC2,USP3,OPTN,ERBB2,ANKMY1,REEP2,CELF1,HHIPL1,TMEM151A,DKK3,SRRM4,WASF3,LYVE1,TCERG1,PADI2,HMGCR,MDFI,MN1,MYO5A,POLG,PRKCB,BCAS3,MSANTD2,DPF2,ELP2,ASIC4,ZFP30,PKNOX2,SLIT1,PALLD,INKA2,ZSCAN29,NSFL1C,TMEM151B,AHCYL2,DAAM2,TNR,WIPF2" MicroRNA hsa-miR-143-5p:Functional MTI Functional MTI miRTarbase 3.08E-22 1.73E-18 6.39E-22 5.89E-21 73 389 "ABCF1,CLK4,XKR4,ADCY2,ESYT2,DOCK11,ST3GAL5,BSN,AKAP5,TBPL1,DBT,YTHDC1,BLOC1S6,G3BP2,DYRK1A,KRBA2,SYT15,HEYL,OPTN,TUBD1,ENPP6,SEC23B,AFF2,SPECC1,MSANTD4,TRAF3IP2,TNRC6A,CNDP1,GRK4,KAT7,FICD,IBA57,LIMS1,GPR155,MAT2A,MKLN1,AFF1,SESN3,OLA1,ZNF655,GPSM2,FITM2,PEX2,PLEKHB2,ZYG11B,PGBD4,SNX22,NCBP3,HSPA4L,PEX26,ANKRD36,ERC1,NPAS3,ZNF621,MAPK8IP3,ZSCAN29,KLHL7,ALG1,WWC1,MGRN1,VWC2,ZNF106,THRA,MEAF6,AGMO,ZNF74,ZNF138,ZNF154,WIPF2,TIGD6,RNF170,NETO2,RNF146" MicroRNA hsa-miR-193a-5p:TargetScan hsa-miR-193a-5p TargetScan 3.15E-22 1.77E-18 6.52E-22 6.00E-21 48 176 "KCNH8,ASIC2,DSCAML1,GRAMD1B,PCDH10,MARCH3,DACT3,RUNX1T1,CNTFR,CCDC144A,FRMPD4,RASSF2,FGF14,MEX3B,GBX2,MMADHC,GRIK3,IL1RAPL1,KCNH1,ASPRV1,MEIS1,MMP16,MYO5A,NOVA1,PBX1,OLA1,CDK14,PPP5C,EPDR1,PROX1,RBBP6,RPE,KIAA0895L,ITSN1,BDP1,MPRIP,GANAB,CNTN2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,ELP5,LAMP5,NETO2" MicroRNA hsa-miR-708-5p:TargetScan hsa-miR-708-5p TargetScan 3.44E-22 1.93E-18 7.13E-22 6.57E-21 47 169 "CPNE2,ACHE,AS3MT,RNF150,PDZD4,BEGAIN,KIAA1614,MTMR3,BSN,CABP7,FMNL3,FOXN3,CNTFR,PITPNM3,GAPVD1,RIMS3,DCC,E2F6,EFNB3,EN2,FOXO3,DKK3,GABRA3,CHL1,GPM6A,MUM1,HNRNPK,C2orf72,KCND3,KCNH1,KCNN3,MDGA1,NFE2L2,NNAT,GPR88,OPHN1,GON4L,RPRD1A,ALG9,ATXN1,CPEB3,IQSEC2,MMS19,CBX5,GDPD5,LMAN2L,PIANP" MicroRNA hsa-miR-28-5p:TargetScan hsa-miR-28-5p TargetScan 3.44E-22 1.93E-18 7.13E-22 6.57E-21 47 169 "CPNE2,ACHE,AS3MT,RNF150,PDZD4,BEGAIN,KIAA1614,MTMR3,BSN,CABP7,FMNL3,FOXN3,CNTFR,PITPNM3,GAPVD1,RIMS3,DCC,E2F6,EFNB3,EN2,FOXO3,DKK3,GABRA3,CHL1,GPM6A,MUM1,HNRNPK,C2orf72,KCND3,KCNH1,KCNN3,MDGA1,NFE2L2,NNAT,GPR88,OPHN1,GON4L,RPRD1A,ALG9,ATXN1,CPEB3,IQSEC2,MMS19,CBX5,GDPD5,LMAN2L,PIANP" MicroRNA hsa-miR-154-3p:TargetScan hsa-miR-154-3p TargetScan 3.54E-22 1.99E-18 7.32E-22 6.74E-21 40 121 "ASIC1,CSMD3,HECW2,ARHGAP20,APC,MARCH3,MTMR3,FOXK1,RUNX1T1,REPS2,FOXN3,ABCG2,CNR1,DOCK4,MAGI2,DYRK1A,RASGRP1,FAM13A,ELAVL2,CAMSAP1,PPARGC1A,GPM6A,GPR26,KLF12,GPR155,MEIS1,JAKMIP3,HCN1,PDE4D,MTMR10,RNF220,RPRD1A,HUNK,AP1AR,MBD5,PDZD2,ARHGAP26,PUM2,ANKS1B,EVI5" MicroRNA hsa-miR-487a-3p:TargetScan hsa-miR-487a-3p TargetScan 3.54E-22 1.99E-18 7.32E-22 6.74E-21 40 121 "ASIC1,CSMD3,HECW2,ARHGAP20,APC,MARCH3,MTMR3,FOXK1,RUNX1T1,REPS2,FOXN3,ABCG2,CNR1,DOCK4,MAGI2,DYRK1A,RASGRP1,FAM13A,ELAVL2,CAMSAP1,PPARGC1A,GPM6A,GPR26,KLF12,GPR155,MEIS1,JAKMIP3,HCN1,PDE4D,MTMR10,RNF220,RPRD1A,HUNK,AP1AR,MBD5,PDZD2,ARHGAP26,PUM2,ANKS1B,EVI5" MicroRNA hsa-miR-214*:mirSVR_highEffct hsa-miR-214*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.61E-22 2.03E-18 7.46E-22 6.87E-21 73 390 "DPF1,ABAT,KLHL32,ADCY6,BEND6,DPY19L2P4,RTL9,OSBPL6,AK2,SPOP,SYNJ2,PTBP2,CDC27,TJP2,SUMF2,MYRIP,PHF14,BLOC1S6,USP3,EBF1,EDN3,PHF20L1,APH1A,AASS,TMEM74,EYA1,WAC,RPS6KC1,ZIC4,SPECC1,ARFGAP2,TMEM8B,SESN1,TDRKH,PACSIN2,NCKAP1L,KCNN3,CREG2,CYP27C1,L1CAM,MBNL1,MOBP,MOG,MRPL42,OGG1,P2RX7,CDK18,GPR173,RETREG1,PLP1,SH3KBP1,PKN2,STRC,RPRD1A,CCDC82,CCDC102B,RPE65,SLC30A10,FERMT1,RCOR3,TNIK,TAB2,CEP68,WSCD1,SLC44A1,ARL10,TNR,SMUG1,ZKSCAN5,CELF4,SPIRE1,PRTFDC1,LAS1L" MicroRNA hsa-miR-588:PITA hsa-miR-588:PITA_TOP PITA 3.67E-22 2.06E-18 7.60E-22 7.00E-21 43 141 "KCNH8,XKR4,USP37,DDX3Y,ATP2B1,NIPA1,CABP7,CNR1,ZC3H11A,DPH1,DYRK1A,EFNB3,EMX2,BRPF3,GHR,TNRC6A,ADAMTS6,KLF12,DOCK7,JAK1,MAP2,GPR137C,PDE3B,HMGCLL1,PPP2R5C,PKN2,PTPRO,FBXW7,SEMA6D,CCDC92,RIMS1,SOX5,MYCBP2,CLSTN2,POGZ,LARP4,DMXL2,TRPS1,UBE2H,ZIC3,STMN4,SLC17A7,SNX27" MicroRNA hsa-miR-4784:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-22 2.10E-18 7.74E-22 7.13E-21 55 231 "CPNE2,ARID1A,RNF157,ADD2,CASKIN1,PHF12,APBB2,CACNA1B,HAP1,METTL6,ARHGEF2,CRMP1,MICAL2,SLITRK5,CTIF,SEC16A,DNM2,EIF4G1,ING4,BSCL2,EIF1,EN2,EPB41L1,MRVI1,AFF2,PDLIM5,CELF1,SRCAP,PRRC2B,ZBTB45,IDH3A,METTL21A,KCND1,MPP2,PABPC1L2A,PFKFB3,SPATA6,TNPO2,BDNF-AS,SH3TC2,NCBP3,HES6,RPH3A,SLC8A1,TRIM67,WDTC1,UNC5B,PEG10,CAMTA2,ASTN2,PSD3,ZFP91,TUBB2A,SF1,ZNF70" MicroRNA hsa-miR-4691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-22 2.10E-18 7.74E-22 7.13E-21 55 231 "ELFN2,ADD1,GRAMD1B,RNF150,PRX,ATP2B3,BMPR1B,CA8,CDH8,SLC22A6,RTTN,C2CD2,TENM4,LRIG1,PLCXD3,RCAN1,TMTC1,CELSR3,SLC43A2,TBC1D16,TMEM132C,FER,UFM1,GABRG2,GBX2,GRID1,GRIK3,FAM107A,HMGB1,C2CD4C,ITPKB,KCNJ4,KIFC3,LSAMP,MAT2A,MID1,MYO5A,NODAL,DDR2,PKD1,PNMA3,KLHL11,HSD11B1L,SLIT1,SMARCE1,NSFL1C,TMEM178B,EXOC7,TMEM151B,NSD1,TNS1,GORASP1,CRB2,SIGLEC10,FAM13C" MicroRNA hsa-miR-572:mirSVR_lowEffct hsa-miR-572:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.90E-22 2.19E-18 8.06E-22 7.42E-21 69 353 "UNC5A,CC2D2A,PITPNM2,FGD2,CNIH2,CARMIL3,BCL2L2,USP6,CD38,CHGA,DNAJB5,MAP4K4,SUMF2,LETMD1,CTH,RUBCN,CYBB,PHYHIP,DGKG,DMPK,OLIG1,TOM1,SGK2,GOLGA7,ELN,ENO2,EPHB1,STX2,EXTL1,TUBB3,GORAB,SUCO,ZCCHC17,NSG2,STARD3,INSM2,MUM1,LRRCC1,MAPT,MBD1,DNHD1,ING3,POLR2F,PRKCG,NDUFS7,PIGG,PTPRN2,RORB,ATAT1,KIF16B,ABLIM3,SLC8A3,CDK5RAP3,MYO16,WDTC1,BDP1,VAMP1,EXOC7,TPCN2,PCDHA5,CDH22,TIAM1,TPM1,FAM155A,NSD2,PRDM2,URM1,FIP1L1,PCBP4" MicroRNA hsa-miR-6792-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-22 2.62E-18 9.64E-22 8.88E-21 55 232 "ELFN2,ADD1,GRAMD1B,RNF150,PRX,ATP2B3,BMPR1B,CA8,CDH8,SLC22A6,RTTN,C2CD2,TENM4,LRIG1,PLCXD3,RCAN1,TMTC1,CELSR3,SLC43A2,TBC1D16,TMEM132C,FER,UFM1,GABRG2,GBX2,GRID1,GRIK3,FAM107A,HMGB1,C2CD4C,ITPKB,KCNJ4,KIFC3,LSAMP,MAT2A,MID1,MYO5A,NODAL,DDR2,PKD1,PNMA3,KLHL11,HSD11B1L,SLIT1,SMARCE1,NSFL1C,TMEM178B,EXOC7,TMEM151B,NSD1,TNS1,GORASP1,CRB2,SIGLEC10,FAM13C" MicroRNA hsa-miR-487b:mirSVR_lowEffct hsa-miR-487b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-22 2.70E-18 9.92E-22 9.14E-21 63 300 "KCNH8,KDM5D,ADARB2,AXIN2,SLC12A5,LTBP4,CPNE5,PPP4R4,DDX3Y,RNF182,DPY19L3,CACNA1G,CACNB4,CALB2,KYAT1,ZBED5,COG1,QKI,SRP14-AS1,SLC4A7,ZNF521,CFAP61,DOCK4,HDAC4,ZEB2,MAGI2,FABP7,FER,FGFR1,SEMA4D,WDR83,PCDH11X,ZNF638,GRM7,RNF165,FAM107A,ZNF667-AS1,NASP,PPP3CB,BCAS3,PEX5,PCMTD2,ATF7IP,SNCA,MBD5,SOX3,KIF1B,NPAS3,SYNE2,WDR7,PCDHGA11,CYB561A3,AP4E1,SLC44A1,TNS1,RFTN2,FLRT1,PLEKHH2,NSD2,FSTL5,PRDM8,PHTF2,FBXO36" MicroRNA hsa-miR-215-5p:TargetScan hsa-miR-215-5p TargetScan 4.86E-22 2.73E-18 1.00E-21 9.24E-21 46 163 "PTCHD1,ALCAM,DPP10,PKP4,DST,CACNA1I,RUNX1T1,NIPBL,IGDCC3,CREB5,ANKRD44,CTH,GAPVD1,DBT,DCC,ALKBH8,CDON,KRBA2,EIF1,PLEKHO1,FAXC,PCDH17,GPR22,LPAR4,RFFL,PTPRT,ARHGAP19,ARHGAP36,IL6ST,CLVS2,KCNK1,KCNK3,LIMS1,MMP16,MYO9A,FTO,PRKACB,APTX,CLSTN1,CPEB4,KIF1B,RAP1GAP2,NKAIN2,DICER1,RICTOR,PHTF2" MicroRNA hsa-miR-192-5p:TargetScan hsa-miR-192-5p TargetScan 4.86E-22 2.73E-18 1.00E-21 9.24E-21 46 163 "PTCHD1,ALCAM,DPP10,PKP4,DST,CACNA1I,RUNX1T1,NIPBL,IGDCC3,CREB5,ANKRD44,CTH,GAPVD1,DBT,DCC,ALKBH8,CDON,KRBA2,EIF1,PLEKHO1,FAXC,PCDH17,GPR22,LPAR4,RFFL,PTPRT,ARHGAP19,ARHGAP36,IL6ST,CLVS2,KCNK1,KCNK3,LIMS1,MMP16,MYO9A,FTO,PRKACB,APTX,CLSTN1,CPEB4,KIF1B,RAP1GAP2,NKAIN2,DICER1,RICTOR,PHTF2" MicroRNA hsa-miR-6513-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-22 2.77E-18 1.02E-21 9.36E-21 73 392 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,MYOM2,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,ABI2,PLEKHA1,MRNIP,IGSF6,ANKFY1,PNMA2,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,GRIK2,IRAK3,IGF1,STMN1,MATN3,CHST6,MDM4,PPM1L,CCDC80,SLC11A2,OCRL,ZNF713,FTO,RETREG2,FAT3,MINDY2,CNTLN,MTMR10,RAB5B,CEP97,SOX6,GALNT10,CLSTN1,SLC1A2,LRRC55,SLC6A9,SEPHS1,ZKSCAN3,FAM126B,MCF2L2,STAU1,ZSCAN29,FAM208A,SLC19A3,NSD1,PCDHA6,ZFP91,ERCC6L2,RFTN2,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20" MicroRNA hsa-miR-6770-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.95E-22 3.34E-18 1.23E-21 1.13E-20 54 225 "TRMT9B,SEMA7A,CDC14B,IGDCC4,FOXK1,ZNF445,LETMD1,AKAP5,RNF14,SLITRK5,KIAA0040,ZC3H11A,CHRDL1,EGR3,ING4,MTSS1L,SLC43A2,SRARP,MRVI1,FAM49B,TRAF3IP2,CRCP,LRRC75A,IDH3A,MAP2,SYT9,SCAMP5,SAMD14,PABPC1L2A,TNPO2,UHRF1BP1,NWD1,ARMH4,KCNIP2,FOXRED2,LIMS2,MAPK8IP3,STX1A,ASTN2,FBXW11,ZNF34,HHIP,ARL10,ZFP91,RBFOX2,TPD52L2,TPM2,TUBB2A,CADM1,MEAF6,SIGLEC10,URM1,ITM2C,WIPF2" MicroRNA hsa-miR-6516-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.09E-22 3.42E-18 1.25E-21 1.16E-20 98 650 "ABCF1,NDRG3,PLEKHG5,SLC24A4,HECW2,HACE1,ZNF578,SEMA6A,AQP6,CDC14B,ASPA,DOCK11,BACH1,BCL7A,FOXK1,PTBP2,CBS,CBFA2T2,MYOM2,CDR1,CCPG1,JAM2,NRXN3,PLAA,TPP1,ACBD5,CPS1,CSNK1G3,PLCXD3,MYADM,GAPVD1,KIAA0513,TMEM170A,DNAL1,PITPNC1,HP1BP3,GUCD1,MTX3,DNAH9,MRO,RASA4,MRNIP,SLC43A2,STX2,ZNF549,ANKMY1,KATNAL1,ZNF585B,SCML2,FECH,TRMO,KBTBD12,CAB39,DISC1,CRCP,GLUL,GNG4,LILRA2,RFFL,KIF3A,RNF165,MIER3,SCRG1,IGF1,IBA57,CCDC80,MXI1,NUCB1,CCSER2,FAT3,TATDN3,NCR3LG1,MTMR10,CEP97,ZNF793,RBBP8,ALG9,ACER3,PTGR2,NCBP3,FNIP1,SLC30A10,SHC4,MAGI3,ATF7IP,SCN3B,FNBP1,LHPP,USP22,BHLHB9,TPM3,PPIL6,SSBP2,RFTN2,USP1,LAT2,EVI5,GAN" MicroRNA hsa-miR-1185:PITA hsa-miR-1185:PITA_TOP PITA 6.83E-22 3.84E-18 1.41E-21 1.30E-20 37 104 "USP37,ATP2B1,CA8,KRIT1,CRY2,HINFP,TENM4,MFAP3L,CEP170,MAGI2,TMCC2,DPH1,DYRK1A,EFNA3,YAF2,FGF14,FOXM1,GABRB3,ADAMTS6,BACH2,IL6ST,MAT2A,FXYD6,RETREG2,OXR1,KCNIP2,SH3GL2,SLC12A2,PEG10,CLASP2,NKAIN2,SEPT8,PRRC2C,TCF12,TRPS1,TUB,WNK3" MicroRNA hsa-miR-526a:PITA hsa-miR-526a:PITA_TOP PITA 7.06E-22 3.97E-18 1.45E-21 1.34E-20 40 123 "RALGAPA1,CLK4,SORCS1,CNTNAP1,NCOA1,ADGRB3,BCL2L2,BTRC,CALM1,NRXN3,NRXN2,AKAP6,DPP6,HIPK3,STAU2,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,CREG2,MN1,ZC3H12B,NRCAM,ARID4A,ROBO2,SNX22,SCN3A,PPP1R9A,NMNAT2,SS18,ANKRD28,CAMSAP2,RPGRIP1L,PUM2,TP53BP2,TPM3,TRIM9,PAK5" MicroRNA hsa-miR-518d-5p:PITA hsa-miR-518d-5p:PITA_TOP PITA 7.06E-22 3.97E-18 1.45E-21 1.34E-20 40 123 "RALGAPA1,CLK4,SORCS1,CNTNAP1,NCOA1,ADGRB3,BCL2L2,BTRC,CALM1,NRXN3,NRXN2,AKAP6,DPP6,HIPK3,STAU2,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,CREG2,MN1,ZC3H12B,NRCAM,ARID4A,ROBO2,SNX22,SCN3A,PPP1R9A,NMNAT2,SS18,ANKRD28,CAMSAP2,RPGRIP1L,PUM2,TP53BP2,TPM3,TRIM9,PAK5" MicroRNA hsa-miR-519c-5p:PITA hsa-miR-519c-5p:PITA_TOP PITA 7.06E-22 3.97E-18 1.45E-21 1.34E-20 40 123 "RALGAPA1,CLK4,SORCS1,CNTNAP1,NCOA1,ADGRB3,BCL2L2,BTRC,CALM1,NRXN3,NRXN2,AKAP6,DPP6,HIPK3,STAU2,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,CREG2,MN1,ZC3H12B,NRCAM,ARID4A,ROBO2,SNX22,SCN3A,PPP1R9A,NMNAT2,SS18,ANKRD28,CAMSAP2,RPGRIP1L,PUM2,TP53BP2,TPM3,TRIM9,PAK5" MicroRNA hsa-miR-519b-5p:PITA hsa-miR-519b-5p:PITA_TOP PITA 7.06E-22 3.97E-18 1.45E-21 1.34E-20 40 123 "RALGAPA1,CLK4,SORCS1,CNTNAP1,NCOA1,ADGRB3,BCL2L2,BTRC,CALM1,NRXN3,NRXN2,AKAP6,DPP6,HIPK3,STAU2,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,CREG2,MN1,ZC3H12B,NRCAM,ARID4A,ROBO2,SNX22,SCN3A,PPP1R9A,NMNAT2,SS18,ANKRD28,CAMSAP2,RPGRIP1L,PUM2,TP53BP2,TPM3,TRIM9,PAK5" MicroRNA hsa-miR-520c-5p:PITA hsa-miR-520c-5p:PITA_TOP PITA 7.06E-22 3.97E-18 1.45E-21 1.34E-20 40 123 "RALGAPA1,CLK4,SORCS1,CNTNAP1,NCOA1,ADGRB3,BCL2L2,BTRC,CALM1,NRXN3,NRXN2,AKAP6,DPP6,HIPK3,STAU2,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,CREG2,MN1,ZC3H12B,NRCAM,ARID4A,ROBO2,SNX22,SCN3A,PPP1R9A,NMNAT2,SS18,ANKRD28,CAMSAP2,RPGRIP1L,PUM2,TP53BP2,TPM3,TRIM9,PAK5" MicroRNA hsa-miR-1296:mirSVR_highEffct hsa-miR-1296:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.23E-22 4.06E-18 1.49E-21 1.37E-20 55 234 "BRAP,INTS2,MTUS1,CC2D2A,ZFYVE28,ASPH,BCL2L2,LRBA,STOML1,ZNF521,CFAP61,CTNND1,DCAF8,DPYSL2,ECM2,ANKRD46,RACK1,TOMM40L,TESK2,FGFR1,UFM1,ERGIC3,GABRA2,TUBGCP4,SLC2A6,AGBL5,MBNL1,BLOC1S2,NRCAM,TBC1D25,PIRT,PDGFRA,GNG2,CAMKV,MDGA2,USP47,DBX2,SLC6A15,RNASE1,PBRM1,GSTCD,SPIN3,CNTNAP3,SFPQ,NTNG1,SLC15A2,RCOR3,SYN1,SYN2,DDHD2,WASHC4,RASD2,TPM1,CADM1,CSDE1" MicroRNA "ACTACCT,MIR-196B:MSigDB" "ACTACCT,MIR-196B:MSigDB" MSigDB 8.11E-22 4.56E-18 1.67E-21 1.53E-20 41 130 "PCDH19,DOC2A,MAP4K3,GAS7,AQP4,IGDCC4,CASK,CHRD,BACH1,PCYT1B,PPP1R16B,PPP6R2,BLOC1S6,LRRC17,ZMYND11,DDX19B,SCRT2,ZNF385B,SYT9,LRP1B,RSPO2,NAP1L1,NME4,OPCML,PDGFRA,ZNF655,SCHIP1,RDX,WDR37,SLC8A2,TRERF1,SOX11,LARP4,ACSL6,DICER1,NR2C2,VSNL1,RICTOR,PARP6,SOCS4,GAN" MicroRNA "ACTACCT,MIR-196A:MSigDB" "ACTACCT,MIR-196A:MSigDB" MSigDB 8.11E-22 4.56E-18 1.67E-21 1.53E-20 41 130 "PCDH19,DOC2A,MAP4K3,GAS7,AQP4,IGDCC4,CASK,CHRD,BACH1,PCYT1B,PPP1R16B,PPP6R2,BLOC1S6,LRRC17,ZMYND11,DDX19B,SCRT2,ZNF385B,SYT9,LRP1B,RSPO2,NAP1L1,NME4,OPCML,PDGFRA,ZNF655,SCHIP1,RDX,WDR37,SLC8A2,TRERF1,SOX11,LARP4,ACSL6,DICER1,NR2C2,VSNL1,RICTOR,PARP6,SOCS4,GAN" MicroRNA hsa-miR-637:PITA hsa-miR-637:PITA_TOP PITA 8.86E-22 4.97E-18 1.82E-21 1.67E-20 42 137 "PITPNM2,CNIH2,CNTNAP1,NCOA1,CACNA1A,CABP7,CACNA2D2,NRXN3,NRXN2,CNTFR,CLIP3,PPP1R16B,RUSC2,SLC12A6,DUSP9,PHC2,DMTN,ANKRD13B,AGAP3,USP21,CPLX2,PPARGC1A,PLPP7,GRIN1,ATXN2L,MAPT,NEUROD2,NFIX,FAM120C,RAB5B,RNF220,SBF1,FUZ,CPEB4,NCDN,STAC2,RALYL,NSD1,FBXL16,RELL2,RBFOX2,SMARCAD1" MicroRNA hsa-miR-4685-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.86E-22 5.54E-18 2.02E-21 1.86E-20 59 269 "FAM43B,XKR4,ADCY5,ADCY6,MTA3,AK2,SEMA4G,ARSE,BACH1,CCNT1,CDH8,SLC22A6,QKI,LRIG1,PITPNM3,PLCXD3,CYBB,SPATA2,SMG7,EMX2,SLC43A2,SRARP,TACC2,TMEM151A,DKK3,SRRM4,FAXC,GJB1,ZNF638,RAPGEF1,GRID1,RFFL,GPR45,BACH2,MIER3,TLX1,SHISA6,KCNQ3,LSAMP,MBNL1,MDFI,MYO5A,GPR137C,ZDHHC22,MTMR10,PTPRG,RAB5B,GTDC1,ATXN7,CLUAP1,LRRC4,DIP2A,TMEM178B,IQCE,RUNDC3B,ZBTB16,TMEM198,RNF146,GAN" MicroRNA hsa-miR-122:PITA hsa-miR-122:PITA_TOP PITA 1.00E-21 5.63E-18 2.06E-21 1.89E-20 37 105 "SORCS1,ADGRB2,CACNB4,CANX,CS,CTNND2,IST1,SPOCK2,G3BP2,DLG2,DLG4,FOXO3,TNRC6A,GPM6B,BACH2,NEGR1,MARK1,MEIS2,ERICH3,NCAM1,OCRL,ZNF827,NLGN3,TNPO2,PTPRB,PPM1E,ARX,SLC4A3,RIMS1,FAM219A,SOX11,TCF4,DICER1,HHIP,PMEPA1,MAP3K12,ADAMTS10" MicroRNA hsa-miR-10a:PITA hsa-miR-10a:PITA_TOP PITA 1.02E-21 5.70E-18 2.08E-21 1.92E-20 47 173 "TMEM132B,ZNF608,KCTD16,DOCK11,BTRC,CAMK2G,MAGI1,NCOR2,RIMS2,ELAVL2,AGAP3,ANKFY1,CHL1,TMEM121B,RNF165,IL1RAPL1,BACH2,HNRNPK,SMAP1,INSYN2,ARHGAP12,NFIX,CNOT4,HCN1,XRN1,PLP1,PURG,MED1,TMEM260,DPF2,FIGN,KCTD17,ITSN1,MBD5,MYT1L,LHFPL4,UNC5D,TRIM2,TIAM1,CSMD1,KAT6B,TRPC1,CADM1,FLRT2,POLR3H,SLC30A4,WNK3" MicroRNA hsa-miR-10b:PITA hsa-miR-10b:PITA_TOP PITA 1.02E-21 5.70E-18 2.08E-21 1.92E-20 47 173 "TMEM132B,ZNF608,KCTD16,DOCK11,BTRC,CAMK2G,MAGI1,NCOR2,RIMS2,ELAVL2,AGAP3,ANKFY1,CHL1,TMEM121B,RNF165,IL1RAPL1,BACH2,HNRNPK,SMAP1,INSYN2,ARHGAP12,NFIX,CNOT4,HCN1,XRN1,PLP1,PURG,MED1,TMEM260,DPF2,FIGN,KCTD17,ITSN1,MBD5,MYT1L,LHFPL4,UNC5D,TRIM2,TIAM1,CSMD1,KAT6B,TRPC1,CADM1,FLRT2,POLR3H,SLC30A4,WNK3" MicroRNA hsa-miR-556-5p:PITA hsa-miR-556-5p:PITA_TOP PITA 1.12E-21 6.31E-18 2.30E-21 2.12E-20 41 131 "RUNX1T1,QKI,TENM4,RIMS4,DOCK4,MAGI2,DNAJB6,ELAVL2,PAN3,ATP8A1,KLF12,MN1,MXI1,NEXMIF,MYT1,ZNF827,STRN3,MAPK3,TMEM260,RDX,RNF220,NUDT11,RXRA,ITSN1,CPEB3,ST3GAL3,SLC4A3,BTBD3,FAM126B,SOX11,TBL1X,RPGRIP1L,TCF12,FRYL,DICER1,SLC44A1,TIAM1,RBFOX2,TUB,MEAF6,WNK3" MicroRNA hsa-miR-1298:mirSVR_highEffct hsa-miR-1298:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.16E-21 6.50E-18 2.37E-21 2.18E-20 54 228 "LRRC7,SRPX,BCAR3,EPB41L5,PLA2G4C,BMP7,CD38,ARMC8,BAG4,MYRIP,GDA,ERC2,COPS7A,DDX46,PDCD6IP,RGPD5,AP4B1,GABRB1,GABRG1,DNER,GHR,STARD3,GRIA2,MFSD2A,DHX35,LRRCC1,LRRTM3,SYTL4,MAP4,MXI1,HNRNPM,NCAM1,PCDH9,ZNF655,ANKRD16,PDZRN4,GRAMD1C,WDR25,CNTLN,ARID4A,RXRA,ITSN1,FHOD3,ZNF365,YPEL4,ZNF667,ANKRD36,SNAP25,NMNAT2,POGZ,KAZN,ZFPM2,NAV3,CASC15" MicroRNA hsa-miR-3913-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-21 6.52E-18 2.38E-21 2.19E-20 70 369 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,MYOM2,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,ABI2,PLEKHA1,MRNIP,IGSF6,ANKFY1,PNMA2,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,GRIK2,IRAK3,IGF1,STMN1,MATN3,MDM4,PPM1L,CCDC80,SLC11A2,OCRL,ZNF713,FTO,RETREG2,FAT3,CNTLN,MTMR10,RAB5B,CEP97,FBXW7,SOX6,GALNT10,CLSTN1,SLC1A2,SLC6A9,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ZFP91,ERCC6L2,RFTN2,RPL7L1,ZNF708,ZNF17,ZNF70,SYNC,EVI5,SIGLEC10,ZDHHC20,GAN" MicroRNA hsa-miR-99a:mirSVR_lowEffct hsa-miR-99a:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 1.18E-21 6.62E-18 2.41E-21 2.22E-20 52 212 "SLC12A5,ZFAT,ARNTL,SYNJ1,MTMR3,MTMR2,LURAP1,UBXN2A,EDRF1,DBI,ALKBH8,PLPPR4,NTM,SUGP2,EPB41L1,CAP2,IP6K2,NOP56,MEGF10,ERAP1,ALDH1L1,ADAM28,C2orf72,DOCK7,INSM1,MOG,MYO7A,PCSK1,BEST3,PURG,ING3,PRKCZ,HYDIN,PTPRN2,TTLL7,CYB561D1,ATP8B4,DOCK10,FBXO11,SLC8A2,SLC14A1,MYO16,MYT1L,KDM4C,TSPYL2,ST5,ANKRD28,UBE3A,VLDLR,BEST1,GAL3ST3,URM1" MicroRNA hsa-miR-6742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-21 6.74E-18 2.45E-21 2.26E-20 63 305 "AS3MT,TXNDC16,AQP6,PRX,SLC4A4,ZNF555,CBS,DIS3L,BTF3L4,COL9A2,CSNK1E,SOCS5,PITPNM3,ZBTB24,RABGAP1L,MTX3,FEM1B,RGS17,SLC43A2,IGSF6,AMOTL2,NCKAP1,KDM2B,CNDP1,LILRA2,SCRG1,KCNK1,MOG,SAMD5,PIK3R1,MTRF1L,TNPO2,FITM2,APTX,STK32A,ZSCAN2,CEP97,PRRT2,GTDC1,STX1B,FAM192A,IL17RB,MAGI3,BDP1,CLUAP1,MCF2L2,SSTR2,NCDN,FAM168A,C3orf70,ALG1,ARL10,CBX5,PARD3,SSBP2,ZNF610,USP1,KLC2,ZBTB16,SLC30A4,LMAN2L,RNF170,GAN" MicroRNA hsa-miR-296-5p:TargetScan hsa-miR-296-5p TargetScan 1.21E-21 6.80E-18 2.48E-21 2.28E-20 42 138 "LRFN1,PPFIA3,ARRB1,CCAR2,CADM3,GPC2,BSN,DDR1,DIRAS1,NUMBL,DLGAP3,IGLON5,CNR1,CNTFR,NRG2,SEC31B,CLIP3,RIMS4,CTIF,DBN1,PHC2,HEYL,MFSD10,FGFR1,GABRB1,INPP5K,CYP46A1,POLL,RNF165,PTPN5,KCNA6,NEUROD2,NOVA2,KCTD15,EPN1,CNNM2,RAD51D,DPF2,PRRT2,ELMO2,NSD1,ADAMTS10" MicroRNA hsa-miR-6077:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-21 7.24E-18 2.63E-21 2.43E-20 60 279 "RNF157,PHF12,ARRB2,LDHD,CANX,TMEM184B,CRY2,CNTNAP2,IST1,SNX29,C8orf37,EN2,MTSS1L,ENPP6,AMOTL2,PNMA2,BRSK1,CRCP,GLYR1,TNRC6A,PRRC2B,GRIN2D,FICD,LINGO1,MIER3,NKD1,ZIC5,RBPJ,TJAP1,SLC35G1,KCNJ10,EPN1,SLC25A23,TNPO2,MINDY2,RAB3A,FIGN,ATXN1,CLSTN1,COA1,MYH15,ANKRD36,UNC5B,ZC3H4,ASTN2,NSD1,ARHGEF12,HIF3A,ZNF106,NACC2,TLR4,ZFP91,TPM3,WRN,ZXDA,DNALI1,WIPF2,SSPN,FXR1,GAN" MicroRNA hsa-miR-5692b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-21 7.43E-18 2.70E-21 2.49E-20 47 174 "ABCF1,XKR4,ADD2,ADD3,TAOK1,STX16,NRP2,FOXK1,CA8,ABCG2,SLC25A27,BTF3L4,PITPNC1,TMTC1,ACSL4,ZBED3,MPP6,TNRC6A,LUZP2,NR3C1,BACH2,MIER3,ZIC5,KLRC3,AFF1,CCDC80,MYBPC1,OCRL,EPDR1,MAPK7,ENOX1,UBR7,ATXN1,HSPA4L,BTBD3,SYP,TACC1,DDHD2,CAMSAP2,TRIM2,SIK3,HHIP,TRPS1,UBE3A,ZFP37,PMEPA1,SLC38A1" MicroRNA hsa-miR-5692c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-21 7.43E-18 2.70E-21 2.49E-20 47 174 "ABCF1,XKR4,ADD2,ADD3,TAOK1,STX16,NRP2,FOXK1,CA8,ABCG2,SLC25A27,BTF3L4,PITPNC1,TMTC1,ACSL4,ZBED3,MPP6,TNRC6A,LUZP2,NR3C1,BACH2,MIER3,ZIC5,KLRC3,AFF1,CCDC80,MYBPC1,OCRL,EPDR1,MAPK7,ENOX1,UBR7,ATXN1,HSPA4L,BTBD3,SYP,TACC1,DDHD2,CAMSAP2,TRIM2,SIK3,HHIP,TRPS1,UBE3A,ZFP37,PMEPA1,SLC38A1" MicroRNA hsa-miR-136-5p:TargetScan hsa-miR-136-5p TargetScan 1.34E-21 7.52E-18 2.73E-21 2.52E-20 58 262 "ELFN2,ADCYAP1R1,PWWP2A,KCTD16,ALS2,DOCK11,ADAM23,DGKI,CCPG1,CACNA2D2,FHL5,OSBPL3,PLCXD3,ARHGEF4,KATNAL2,RABGAP1L,DLG3,CPEB2,COPS4,PLEKHO1,MRVI1,AGAP2,PPARGC1A,GNAS,GNG3,CNDP1,GPR26,GRID1,C5orf24,PLD5,CREG2,LIFR,NOVA2,KCNK10,PAX6,PBX1,PLXNB1,FAT3,OCIAD1,RDX,RET,ERI2,RGS4,RPRD1A,RIMKLA,NUBPL,LRRC55,CPEB4,KDM3A,PEG10,NPAS3,GANAB,MGRN1,RPGRIP1L,PSD3,HHIP,GDPD5,RGS7BP" MicroRNA hsa-miR-3122:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-21 7.64E-18 2.78E-21 2.56E-20 70 370 "XKR4,PLEKHH1,TXNDC16,DNAH17,SYNJ2,ISPD,MYOM2,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,MRO,ABI2,PLEKHA1,MRNIP,IGSF6,ANKFY1,PNMA2,MSANTD4,TRAF3IP2,CRCP,TNRC6A,GNG4,GRIK2,IRAK3,IGF1,STMN1,MATN3,MDM4,PPM1L,CCDC80,SLC11A2,OCRL,ZNF713,FTO,RETREG2,FAT3,CNTLN,MTMR10,RAB5B,CEP97,FBXW7,SOX6,GALNT10,CLSTN1,SLC1A2,SLC6A9,SEPHS1,ZKSCAN3,MCF2L2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,ZFP91,ERCC6L2,RFTN2,RPL7L1,ZNF708,ZNF17,ZNF70,SYNC,EVI5,SIGLEC10,ZDHHC20,GAN" MicroRNA hsa-miR-886-5p:mirSVR_lowEffct hsa-miR-886-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.45E-21 8.16E-18 2.96E-21 2.73E-20 69 361 "TTYH1,ASPHD1,ARNTL,LINC00173,ADAM15,ADGRB1,CA12,CALM1,VSTM2A,TJP2,LETMD1,RASGEF1C,MYADM,POM121,SGSM2,DMPK,DPH1,EGR3,C3orf18,OLIG2,RASL12,TUBB4A,RACK1,FCGRT,SMC2,TPK1,TBR1,SIGLEC8,USP19,TCERG1,GLI2,GNAO1,GNG3,GRIN1,MAN1B1,HSD17B1,SCRT2,KCNA6,GPR62,MT3,MYT1,FXYD7,NKX2-2,LOC100128398,SLC26A11,CNNM2,BCAS3,GDPD2,RGS12,KCTD17,ASIC4,SLC30A10,CPEB3,SLC2A5,SLC6A1,SLC6A9,CLSTN2,ZC4H2,ACSBG1,PCDHB9,HIF3A,DICER1-AS1,THBS4,SEZ6L,METTL3,TSN,TSC1,LAT2,CASC15" MicroRNA hsa-miR-5692a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-21 9.20E-18 3.34E-21 3.08E-20 61 289 "ARID1A,WDR35,TXNDC16,FOXK1,ZNF555,MAP7,PRC1,CD38,STOML1,DYRK1A,FEM1B,PLEKHO1,RTN3,ZNF585B,DOT1L,GABRA3,ZNF559,SRRM4,RAPGEF1,ATXN2L,HLF,ZIC5,JAK2,LRP1B,NAP1L1,GPR137C,PDE3A,TMOD2,LRP12,PSAT1,SH3KBP1,PPARA,PKN2,PLEKHB2,SH3TC2,ENOX1,RBBP6,SLC25A36,TMLHE,ACER3,TMEM156,CSRNP3,ATXN1,SGK1,SON,HECW1,ZBTB43,ZNF621,DDHD2,TBCEL,ZMAT3,ACTR6,TPD52,UBE3A,MEAF6,ZNF711,SMARCAD1,ZXDA,WIPF2,HNRNPA3,NETO1" MicroRNA hsa-miR-1976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-21 1.13E-17 4.11E-21 3.78E-20 83 501 "AS3MT,RNF157,ESYT2,CDC14B,SLC7A14,KIAA1614,SLC4A4,ALDH7A1,BCL2L2,GPR146,RAB3C,RTTN,BAG4,CREM,ENTPD4,HINFP,CSNK1E,RIMS4,KIAA0408,CTIF,DNAL1,RABGAP1L,WDPCP,CNNM1,MRNIP,RGS17,PLEKHO1,SLC43A2,TMEM132C,FKTN,FDFT1,FOXO3,AFF2,TMEM151A,CRCP,KIAA1958,CNDP1,GRK4,KIF3A,RNF165,HMGB1,ZDHHC15,EID2B,NCOA7,LSAMP,ALDH1L2,HMGCLL1,MTRF1L,EPDR1,APTX,ZSCAN2,TMEM231,ZNF844,NWD1,GTDC1,CYB561D1,PGBD4,UEVLD,RXRA,FAM192A,SCN2B,HSPA4L,ZFP30,PEX26,ZNF667,CLUAP1,MPRIP,AGTPBP1,SATB2,TPCN2,PCDHA6,ZNF106,ARL10,ERCC6L2,USP1,MEAF6,AGMO,ZNF70,ZBTB16,LMAN2L,WIPF2,MPPE1,SSPN" MicroRNA hsa-miR-627-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-21 1.15E-17 4.19E-21 3.86E-20 63 308 "RALGAPA1,ADCYAP1R1,RNF150,SPOP,ABCD2,GPAM,ASCL1,RASL11B,SYT6,DLGAP2,VCAN,PLCXD3,ZSCAN23,YTHDC1,BLOC1S6,TMTC1,EIF1,EPHB1,REEP2,HHIPL1,GABRA1,GABRG2,FAXC,GCK,CRCP,PRRC2B,NUDT21,HAS2,SLC6A17,SLC35G1,MID1,NCAM2,NEUROD1,NOVA2,P2RX7,OLA1,EPB41L4B,PRKCB,ZSCAN2,TMEM100,UEVLD,ATXN1,FNIP1,SH3BP2,CHD9,IGSF9B,RBM26,EPB41L3,LRRC4,EXOC7,DDHD1,TNS1,TUBB2A,ZNF610,UBE2H,DHX33,SLC30A4,CADM2,NAV2,FAM13C,PAK5,PHTF2,JMJD1C" MicroRNA hsa-miR-518f:mirSVR_highEffct hsa-miR-518f:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.11E-21 1.18E-17 4.29E-21 3.95E-20 55 239 "TTYH1,TKTL1,AXIN2,LRFN2,ZNF608,PCDH19,ANK1,PPFIA1,CASK,CFAP410,LGI1,CHGA,AKAP6,SMARCAL1,ACBD5,SOCS5,DTNA,ANKRD13B,GMPR2,ACSL4,GORAB,FHL1,TACC2,NSG2,SYT17,KDM2B,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,ZC3H12B,NDUFA5,ZNF827,PPP3CB,APTX,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,TBCEL,NSD1,TGFBR3,HEY2,KAT6B,TPD52L2,TSN,PLEKHH2,KCNK12,EMSY,PRDM2,PRTFDC1,PARP11" MicroRNA hsa-miR-491-5p:PITA hsa-miR-491-5p:PITA_TOP PITA 2.13E-21 1.20E-17 4.34E-21 4.00E-20 37 107 "ARID1A,ZBTB10,ADGRB1,BCL2L2,CFL2,NRXN2,ZNF385A,SEC24C,C2CD2L,MAGI2,SRGAP3,DMPK,EFNA3,APH1A,EGR3,TMEM35A,AGAP3,GAP43,SRCAP,TNRC6A,IL1RAPL1,KAT7,MIER3,KCND3,MAT2A,MEIS2,MN1,GIT1,PDE1B,PDGFRA,FAM126B,MYT1L,KIF21B,STAC2,SYN1,CAMTA1,TCF7" MicroRNA hsa-miR-450a-1-3p:Functional MTI Functional MTI miRTarbase 2.15E-21 1.21E-17 4.38E-21 4.04E-20 72 392 "XKR4,PLEKHH1,TXNDC16,DNAH17,LDHD,SYNJ2,ISPD,MYOM2,SUMF2,CLOCK,PPP1R16B,USP6NL,GAPVD1,DNAL1,DNAH9,SLC29A4,GPR61,MRO,ABI2,PLEKHA1,MRNIP,IGSF6,ANKFY1,PNMA2,MSANTD4,TRAF3IP2,CRCP,GNG4,GRIK2,IRAK3,IGF1,MATN3,MDM4,PPM1L,CCDC80,SLC11A2,OCRL,ZNF713,PDE3A,FTO,RETREG2,FAT3,PRKAB2,CNTLN,MTMR10,RAB5B,CEP97,SETD5,SOX6,GALNT10,CLSTN1,SLC1A2,SLC6A9,SEPHS1,ZKSCAN3,MCF2L2,TAB2,ZSCAN29,FAM208A,SLC19A3,PCDHA6,NACC2,ZFP91,ERCC6L2,UBC,RPL7L1,ZNF708,ZNF17,ZNF70,EVI5,SIGLEC10,ZDHHC20" MicroRNA hsa-miR-125a-5p:mirSVR_highEffct hsa-miR-125a-5p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.17E-21 1.22E-17 4.42E-21 4.07E-20 80 471 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,CNIH2,SHTN1,ARNTL,CDK13,ASPH,ZBTB10,ATM,USP2,P2RX6,AIFM1,SULT4A1,LY86,SLC4A8,HINFP,MICAL2,KIAA0586,IST1,ZEB2,RABGAP1L,SRRM1,SPEG,SEMA4D,CGREF1,OGA,KIAA1841,RABL2A,AGBL5,MSL1,ZNF546,KCNB1,KCNK2,KCNMA1,KCNN2,KLRC2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,PAK3,C11orf49,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,SEC61A2,TMLHE,ATP8B4,COPZ1,BCAN,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,SEPT8,DIP2A,VWA3A,C18orf54,MTMR14,TLR4,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,STMN4,EPM2A,TIGD6,IFT88,SLC4A10" MicroRNA "GTGTTGA,MIR-505:MSigDB" "GTGTTGA,MIR-505:MSigDB" MSigDB 2.26E-21 1.27E-17 4.59E-21 4.23E-20 36 101 "ALS2,TMEM263,ARNTL,DDX3Y,ATP2B1,ATP2B2,CAMK2D,CANX,USP6,FAM19A5,GDA,KIAA0408,NTM,ELAVL2,CELF1,ZMYND11,CYP46A1,CAMK2N2,MBNL1,MXI1,MYCN,PCDH9,PDE4D,PDPK1,GPR85,PMP22,STRN3,USP47,FIGN,EPN2,SLC12A2,SON,ARHGAP26,TTBK2,ZIC2,USP32P2" MicroRNA hsa-miR-331-3p:mirSVR_highEffct hsa-miR-331-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-21 1.55E-17 5.59E-21 5.15E-20 60 283 "AS3MT,CSMD3,GALNT13,FAHD2CP,MTUS1,SPOP,SEMA7A,RGS9,NRP2,KALRN,CD38,ZMYM4,GPRASP1,GAPVD1,EARS2,TBC1D5,DRD1,ELN,NRN1,RPS6KC1,SCML2,FCGR3A,BAIAP2,NELFCD,NBEA,OGA,GAD1,IP6K3,DISC1,NEU3,ATF7,COQ10A,USP54,LIX1,KIF5A,MEIS1,THYN1,MYO7A,ZC3H12B,PDE1C,GNG2,SMIM7,TUG1,STRC,RIC8B,RPE,ABCA11P,WLS,KIF16B,ANKRD6,RAB3GAP1,SLC8A3,TMEM132D,TRERF1,C18orf54,SLC13A3,TRIM9,FTSJ1,PRDM8,ADAMTSL3" MicroRNA hsa-miR-1304:PITA hsa-miR-1304:PITA_TOP PITA 2.92E-21 1.64E-17 5.94E-21 5.47E-20 41 134 "KIAA1324,LRRC7,OGT,CAPRIN2,SLC4A4,CACNA1D,CHM,B4GALT6,CLTA,CREB5,CLIP3,TOMM20,ZEB2,SLC12A6,EPB41L2,BACH2,MEIS2,AFF1,ZC3H12B,CCSER2,SH3KBP1,POU3F2,WBP1L,SYTL2,RAB5B,USP47,SATB1,ATXN7,CPEB3,BCAN,SOX5,ZHX3,DICER1,TIE1,NR2E1,TRPS1,TSC1,NAV3,SLC17A6,GOPC,MSRB3" MicroRNA "GTTATAT,MIR-410:MSigDB" "GTTATAT,MIR-410:MSigDB" MSigDB 3.25E-21 1.83E-17 6.61E-21 6.09E-20 34 90 "FMNL2,CASK,NUMB,ATP2B2,NRXN3,FAM19A5,QKI,CREB5,ST18,DPYSL2,YAF2,PHF20L1,MSTN,GRIA2,NR3C1,MAP4K5,HMGB1,ITPKB,LAMP2,SCAMP5,NTRK2,PCDH8,ATG16L1,RDX,CPEB3,CPEB4,SOX1,SP4,C11orf87,SYN2,ANKRD12,DOCK9,TMEFF2,KAT6A" MicroRNA hsa-miR-663b:mirSVR_highEffct hsa-miR-663b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.32E-21 1.86E-17 6.74E-21 6.21E-20 60 284 "CSMD2,GALNT13,ADD2,NR0B1,OSBPL6,ALAD,AMPD2,MYH7B,SLC2A11,RGS9,DST,CACNA1G,CERS5,EPS15L1,MAP4K4,COL9A1,SLC4A8,CSF3R,ATRNL1,PHF19,IP6K1,EDNRB,FCF1,EFNB3,MRPL10,NRN1,ACSL4,ATP8A2,ADAM28,FREM1,BRD8,GRIA2,GSN,NCKAP1L,RBPJ,KNDC1,OLFM3,MN1,ERICH3,GIT1,FXYD6,PDGFRA,KLK6,SIDT1,RFX5,RPL15,TMEM156,MIR124-2HG,FAM214B,SEPHS1,EMC1,PEG10,ZSCAN29,TACR1,FAM208A,LEFTY2,GZF1,TPD52,ZNF23,FIP1L1" MicroRNA hsa-miR-5096:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.49E-21 1.96E-17 7.08E-21 6.52E-20 62 302 "SERPINA3,XKR4,ADCYAP1R1,PCDH19,TAOK1,TRMT9B,C6orf89,API5,ARSE,CADPS,ATP1A2,ZNF445,FOXN3,AKAP6,SEC31B,ANKRD44,CSNK1E,LONRF1,KIAA0586,DBT,JAKMIP2,GNE,WDPCP,ZIC4,FOXF2,TRMO,MPP6,TRAF3IP2,MYOZ2,TNRC6A,PRRC2B,PTPRT,RNF165,DDX19B,IL6R,SLC6A17,POU3F2,MINDY2,ZNF793,ZYG11B,C12orf49,PGBD4,UEVLD,PTGR2,FNIP1,SH3BP2,ZCCHC24,CLUAP1,KIF1B,FGD4,ALG1,AGTPBP1,SATB2,ZNF384,MEAF6,CLDND1,ZNF708,ZNF70,SLC38A1,PHTF2,MSRB3,GAN" MicroRNA hsa-miR-502-5p:PITA hsa-miR-502-5p:PITA_TOP PITA 3.71E-21 2.09E-17 7.54E-21 6.94E-20 40 128 "OGT,CARMIL3,LDLRAD4,RBM39,NCOR2,RIMS4,DAPK1,SMG7,SRGAP3,EIF4G2,ELAVL3,PAN3,AKAP3,DOT1L,RAB30,BACH2,MIER3,KITLG,HS6ST3,MXI1,NEUROD2,NFIA,CNOT4,ZNF827,PLP1,MED1,PTCH1,PTPRE,FAM120C,FIGN,CASC3,SRPK2,NUDT10,SYT4,ANKRD12,TCF4,SIRT1,RIMBP2,ZNF384,HNRNPA3" MicroRNA hsa-miR-331-3p:Functional MTI Functional MTI miRTarbase 4.12E-21 2.31E-17 8.35E-21 7.69E-20 73 406 "ARID1A,AP2A2,ZNF608,APBB1,DGKZ,STX16,NRP2,CAMK2G,SLC25A14,CLDN10,ARHGEF1,NEURL1,TAOK2,QKI,PLCH2,CTNND1,EARS2,TOMM20,FBXL5,SEC16A,TOM1,ABI2,EIF4G2,EN2,EPB41L2,ERBB2,WAC,SCML2,APOPT1,USP21,ZNF512,GFER,GGT7,GNAS,PRRC2B,GPR26,PTPRT,MIER3,TJAP1,ITPKB,MAP4,MARK3,HNRNPM,NELL2,OPRL1,PDPK1,TNPO2,DEF8,PTPN13,RDX,CARF,HES6,SFPQ,SH3BP2,AMBRA1,SEC31A,SPTAN1,SPTB,SS18,NCDN,GSE1,FAM168A,ZC3H4,EXOC7,SMG6,TMEM151B,SIRT1,VAV2,KLC2,POLR3H,WNK1,STOX2,NUP214" MicroRNA hsa-miR-200b-3p:Functional MTI Functional MTI miRTarbase 4.12E-21 2.31E-17 8.35E-21 7.69E-20 48 186 "NLGN4X,TXNDC16,CDC14B,ARHGDIA,STX16,SEPT7,QKI,BAG4,PHF14,RASSF2,MATR3,ZEB2,MAMLD1,DNAJB6,ABI2,ACSL4,DLC1,FOXG1,FLT1,CELF1,CAB39,WASF3,SESN1,MALT1,FERMT2,RASSF8,TJAP1,PDPK1,PKD1,MAPK7,UHRF1BP1,PTPRD,OXR1,ZFHX4,WDR37,ELMO2,MBD5,KIF13A,ZNF621,ERBIN,CAMSAP2,TCF7L2,ZEB1,PSD3,ZFPM2,ZMAT3,TUBB2A,HNRNPA3" MicroRNA hsa-miR-196a-5p:Functional MTI Functional MTI miRTarbase 4.17E-21 2.34E-17 8.45E-21 7.79E-20 62 303 "BRAP,MTUS1,FAM135A,ANXA7,APP,IGDCC4,ATP1A1,BACH1,BCS1L,NRP2,RAB29,CALM1,CANX,FMNL3,KMT2C,NRXN1,SPATA2,ZBTB24,MED12,TRAPPC9,DCTN4,KATNAL1,REEP2,TUBA1B,FKTN,SARAF,SALL3,USP19,MSL3,GLUL,PRUNE2,GRIK4,ITGAV,SLC35G1,KPNA5,IPO5,MAP4,SYT9,MPP2,NAP1L1,MTRF1L,ATG16L1,RDX,RFX5,ARMH4,LGR4,SBF1,KIF27,TRA2B,HSPA4L,SH3GL3,CPEB3,RUFY2,SLC6A8,PALLD,MYCBP2,TAB2,KLHL7,TGFBR3,TRPC3,SMARCAD1,C12orf4" MicroRNA hsa-miR-210:mirSVR_highEffct hsa-miR-210:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.40E-21 2.47E-17 8.91E-21 8.21E-20 49 194 "CC2D2A,NOL4,ADGRB3,ST3GAL5,RUNX1T1,CDH18,CHN1,CNRIP1,IP6K1,GIT2,DLX1,NR1D2,EFNA3,ABCA8,TAOK3,CORO2B,TOMM40L,C2orf88,AIFM3,DIDO1,PRDM5,ARHGAP36,HMGB1,SLC35G1,KCNK1,KCNK2,KLC1,IPO5,STMN1,MARK1,NEFM,SEMA5B,FAM218A,TTC13,RNASEL,CARF,WLS,ZFP2,ST3GAL3,SLC6A1,SLC8A3,ATF7IP,SMARCA4,FGD4,USP32P1,ZFP91,DCBLD1,CIAPIN1,MPPE1" MicroRNA "AGGCACT,MIR-515-3P:MSigDB" "AGGCACT,MIR-515-3P:MSigDB" MSigDB 4.51E-21 2.53E-17 9.13E-21 8.41E-20 33 85 "OGT,CACNA1D,FMNL3,QKI,CLOCK,CS,DYRK1A,DCTN4,EPB41,JPH4,LRRC37A6P,PCDH17,XRN1,MDGA2,PTPRG,RIPOR1,SLC6A15,CYB561D1,SEMA6D,HOGA1,BTBD3,YPEL4,SOX11,C11orf87,ITPRID2,SYT1,SYNE1,ARHGEF12,TRIM9,DPYSL5,LRP8,KAT6A,GAN" MicroRNA hsa-miR-4796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-21 2.70E-17 9.74E-21 8.97E-20 60 286 "ADAR,FMNL2,PLEKHH1,FZD9,SEMA7A,CAPRIN2,NIPA1,EPS15L1,ZFYVE9,BTF3L4,CPS1,UBXN2A,CTNND1,PHF19,KIAA0513,FBXL5,SH3GLB1,KMT5B,EIF5,ELAVL2,CERCAM,F3,HHIPL1,SYT17,C15orf41,FAXC,SESN1,TNRC6A,CBX1,LUZP2,PRUNE2,FUT10,NR3C1,SOWAHA,METTL21A,KCNB1,KCNN1,MAPT,PFKP,ZFYVE21,LRP12,PRKCB,SLC22A23,PXK,RAB5B,CEP97,RAP1GDS1,ATXN1,TMEM200C,RUFY2,TRIM67,FAM126B,SP4,NACC2,TPM4,RGMB,TUBB2A,EMSY,WNK3,NETO2" MicroRNA hsa-miR-182-5p:Non-Functional MTI Non-Functional MTI miRTarbase 4.82E-21 2.71E-17 9.75E-21 8.98E-20 47 179 "ADCY6,BARD1,SLC25A14,FMNL3,CLOCK,CREB5,PITPNM3,NTM,RBM12,PCOLCE2,TUBD1,NRN1,TUBA1B,FOXF2,FOXO3,USP16,STAG2,CHL1,GABRB1,ATP8A2,MALT1,TNRC6A,NR3C1,PPM1L,MITF,CTNNA3,NPTX1,PCDH8,PFKFB3,PIK3C2A,RAB5B,RAD17,SEC61A2,FBXW7,CASC3,SLC11A1,SMARCD3,ANKRD36,LRRC4,SIN3B,SATB2,TIAM1,TP53BP1,CADM1,RPL7L1,TCEAL7,EVI5" MicroRNA hsa-miR-1236-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.85E-21 2.72E-17 9.81E-21 9.03E-20 55 243 "SLC25A25,GRAMD1B,SPOP,PRX,ATP2B3,GPR146,DIS3L,SLC22A6,CLTC,PNKD,SH2B1,TENM4,PITPNM3,UBXN2A,PLCXD3,GAPVD1,CENPL,C2CD2L,RCAN1,ABI2,EPB41,ZNF391,TBC1D16,TMEM175,CELF1,NSG1,GABRG2,ZNF638,GPR26,PTGDR2,HMGB1,IBA57,MYBPC1,NODAL,NOVA2,NPTX1,KSR2,TMOD2,KCTD15,PLCL1,PKIA,CNNM2,PTPRN2,TMEM156,ATXN1,EPN2,LIMCH1,VAMP1,TMEM178B,KLHL4,ZEB1,KAT6B,XPO1,PRDM10,NUP214" MicroRNA hsa-miR-6829-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.87E-21 2.74E-17 9.86E-21 9.08E-20 64 322 "MTA3,SLC4A4,GYG2,CACNA1A,RAB3C,IGLON5,RTTN,KIAA0408,TMEM170A,ZBTB24,C2CD2L,RABGAP1L,TMCC2,KRBA2,CNNM1,RGS17,TUBD1,REEP2,FKTN,TESK2,PDLIM5,MSANTD4,TMEM151A,NCKAP1,GGT7,RAB40B,CNDP1,RAPGEF1,DDX19B,HMGB1,ZDHHC15,NKD1,METTL21A,LIMS1,GPR155,MOG,NKX2-2,MTRF1L,EXOSC10,FITM2,APTX,PIGG,PTAFR,ZSCAN2,PRRT2,MRPS18A,KLHL11,GALNT10,PEX26,PKNOX2,SLC6A8,FAIM2,CLUAP1,AJAP1,AGTPBP1,PCDHA6,ZNF106,ARL10,ERCC6L2,PARD3,SSBP2,AGMO,LMAN2L,GAN" MicroRNA hsa-miR-6791-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.87E-21 2.74E-17 9.86E-21 9.08E-20 64 322 "MTA3,SLC4A4,GYG2,CACNA1A,RAB3C,IGLON5,RTTN,KIAA0408,TMEM170A,ZBTB24,C2CD2L,RABGAP1L,TMCC2,KRBA2,CNNM1,RGS17,TUBD1,REEP2,FKTN,TESK2,PDLIM5,MSANTD4,TMEM151A,NCKAP1,GGT7,RAB40B,CNDP1,RAPGEF1,DDX19B,HMGB1,ZDHHC15,NKD1,METTL21A,LIMS1,GPR155,MOG,NKX2-2,MTRF1L,EXOSC10,FITM2,APTX,PIGG,PTAFR,ZSCAN2,PRRT2,MRPS18A,KLHL11,GALNT10,PEX26,PKNOX2,SLC6A8,FAIM2,CLUAP1,AJAP1,AGTPBP1,PCDHA6,ZNF106,ARL10,ERCC6L2,PARD3,SSBP2,AGMO,LMAN2L,GAN" MicroRNA hsa-miR-508-3p:PITA hsa-miR-508-3p:PITA_TOP PITA 5.53E-21 3.11E-17 1.12E-20 1.03E-19 42 143 "CPNE2,FMNL2,SORCS1,CDC14B,NCOA1,NUMB,BSN,CACNB2,SEPT7,CFL2,CNN3,ABI3BP,PLCXD3,CEP170,DLG2,PCOLCE2,NCALD,PHYHIPL,MSTN,CECR2,GRIA2,MITF,NEUROD2,PCMT1,PDE4D,PIK3R1,TRHDE,LRP12,MINDY2,SATB1,SCN2A,CPEB3,ABLIM3,PPP4R3A,LMO3,SRPK2,CLASP1,SYNE1,ARHGEF12,TSC1,RNF103,PHTF2" MicroRNA hsa-miR-658:mirSVR_highEffct hsa-miR-658:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.76E-21 3.24E-17 1.17E-20 1.07E-19 50 203 "KIDINS220,ZNF578,SUGT1P4-STRA6LP-CCDC180,CNTNAP1,MARCH3,CAPRIN2,KIAA1549L,NRXN2,TPP1,CNTFR,TMEM132C,ATP6V1H,PLCD4,RNF165,PTPN5,AGBL5,MSL1,TJAP1,LINC00634,MT3,NF1,NUMA1,RETREG1,APTX,DPF2,UEVLD,RPS20,CCDC92,YPEL4,UNC80,CLASP2,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,DICER1,TMOD1,SEZ6L,TRIO,ZMYND8,DCBLD1,PRR18,FLRT1,SF1,PPP1R3F,UBE3B,CASC15" MicroRNA hsa-miR-3202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.38E-21 3.58E-17 1.29E-20 1.19E-19 58 270 "ARID1A,ELFN2,HECW2,TAOK1,SEMA4G,PDXK,ARRB2,DPY19L3,RUNX1T1,CBFA2T2,ZNF385A,DCAF4,FAM131B,IP6K1,SPATA2,APH1A,MRO,GCK,PRRC2B,RAPGEF1,ZNF496,NXPH3,TNFAIP8L3,C5orf24,MAG,ZFYVE27,PABPC1L2A,NFIX,GPR173,PKM,KCTD15,FXYD1,PACSIN1,PTPA,SETD5,SGK1,SH3BP2,AMBRA1,R3HDM2,PEX26,TRIM67,IQSEC2,CDK19,SS18,MAPK8IP3,FAM168A,USP22,AHCYL2,TMEM9,NACC2,WBP2,TMPRSS5,UBTF,ZNF708,INTS3,CIAPIN1,URM1,NAV2" MicroRNA hsa-miR-486-5p:TargetScan hsa-miR-486-5p TargetScan 6.40E-21 3.59E-17 1.29E-20 1.19E-19 39 123 "NCKAP5,MTA3,HECW2,MARCH4,ARHGAP5,DYNLL1,CLDN10,ARMC8,PLXNA4,GAPVD1,ELMSAN1,GRIN3A,RBM12,CELSR3,ELAVL2,EPB41L1,GPR153,CSPG5,GABRB3,INPP5K,RFFL,GUCY1A2,MYLK2,IGF1,KCNQ3,MARK1,NFYA,HCN1,PDE4A,PIK3R1,FAT3,PPP3CB,CNKSR2,BTBD3,PRRC2C,C5orf64,NR2C2,CADM1,FLRT2" MicroRNA hsa-miR-939-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.70E-21 3.76E-17 1.35E-20 1.25E-19 76 439 "AS3MT,SLC24A4,HACE1,PRX,ARSE,SLC4A4,CBS,SLC16A4,ZNF445,DIS3L,BTF3L4,NRG2,CSNK1E,SUSD5,UBXN2A,GAPVD1,CENPL,ZBTB24,RUSC2,RABGAP1L,MTX3,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,ANKFY1,TRMO,FUT9,NCKAP1,CRCP,GPR75,KDM2B,CNDP1,LILRA2,DDX19B,SCRG1,DOCK7,ITPKB,KCNK1,KCNN3,MOG,SAMD5,SLC11A2,PIK3R1,MTRF1L,TATDN3,FITM2,APTX,PEX2,ZSCAN2,GTDC1,KLHL11,KLHDC8A,STX1B,ZNF331,FAM192A,BDP1,CLUAP1,EMC1,ADAMTS17,ALG1,AGTPBP1,AHCYL2,ARL10,CBX5,PARD3,PPIL6,SSBP2,UBC,TBC1D15,KLC2,ZBTB16,TRIM16L,RNF170" MicroRNA hsa-miR-1197:PITA hsa-miR-1197:PITA_TOP PITA 6.73E-21 3.78E-17 1.36E-20 1.25E-19 48 188 "XKR4,ADD3,UNC5A,DDX3Y,DPY19L3,FOXN3,QKI,CREB5,SOCS5,RBM12,PRKAG2,AFF2,GABRG2,PPARGC1A,TNRC6A,GPD1,TMEM25,IL1RAPL1,FRMD3,IBA57,TUBB2B,MAT2A,MEIS2,NFIX,NTRK3,OPCML,PCMT1,MAPK10,TMEM260,PTPRO,GTDC1,SLC25A36,SCN2A,CLSTN1,CCDC88A,SP4,LHFPL4,TEX2,CDK19,CLASP2,NKAIN2,PLCB1,DAAM2,KAT6B,EIF4ENIF1,SCG2,CERS6,SENP7" MicroRNA hsa-miR-429:Functional MTI Functional MTI miRTarbase 7.20E-21 4.05E-17 1.45E-20 1.34E-19 43 151 "NLGN4X,TXNDC16,CDC14B,ARHGDIA,STX16,SEPT7,QKI,BAG4,PHF14,RASSF2,ZEB2,MAMLD1,DNAJB6,ABI2,ACSL4,DLC1,CELF1,CAB39,WASF3,SESN1,MALT1,RASSF8,TJAP1,PDPK1,PKD1,MAPK7,UHRF1BP1,PTPRD,ZFHX4,WDR37,ELMO2,MBD5,KIF13A,SOX2,ZNF621,ERBIN,CAMSAP2,TCF7L2,ZEB1,PSD3,ZFPM2,ZMAT3,TUBB2A" MicroRNA hsa-miR-571:PITA hsa-miR-571:PITA_TOP PITA 7.46E-21 4.19E-17 1.50E-20 1.39E-19 34 92 "DSCAML1,APLP1,ARHGAP5,ATP2B1,CALM1,DBN1,ERBB4,DOT1L,KCNMA1,KTN1,MAP2,MAT2A,NLGN3,LAMA1,RAB5B,OXR1,GTDC1,ZFHX4,ROBO2,RTKN,KCNIP1,KIF21B,HECW1,RAP1GAP2,LARP4,CAMSAP2,FAM208A,TCF4,RPGRIP1L,SLC44A1,SF1,FMN2,DPYSL5,ST7" MicroRNA hsa-miR-1273e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.58E-21 4.26E-17 1.53E-20 1.41E-19 78 460 "ABCF1,NDRG3,HACE1,SORCS2,OSBPL8,ANK1,LCORL,APAF1,TNRC6C,AQP6,IGDCC4,ASTN1,ATM,PTBP2,CBS,SLC16A4,SUMF2,IFFO1,ACBD5,CTNND1,DCAF4,MYADM,KIAA0513,SCRN1,DNAL1,HP1BP3,DNAH9,HEYL,MRO,RASA4,ANKMY1,FAM198B,ZNF585B,DLC1,ZNF589,GABRA3,NCKAP1,GNG4,NUDT21,KIF3A,ZNF491,CCDC80,MXI1,NCAM2,NUCB1,FAT3,PPP2R5E,PRKACB,ZNF844,CEP97,RBBP8,SEC61A2,KLHDC8A,ALG9,ROBO1,ELP2,SNX22,ZNF354C,TRAPPC13,PEAR1,SEPHS1,SLC8A1,SCN3B,MCF2L2,TAB2,ACSBG1,ANKRD12,TAL1,AHCYL2,HHIP,RASD2,ZKSCAN5,CADM1,TBC1D15,LAT2,ZNF74,CADM2,PARP11" MicroRNA hsa-miR-2467-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.85E-21 4.97E-17 1.78E-20 1.64E-19 76 441 "ABCF1,NDRG3,PLEKHG5,HECW2,TRMT9B,KIAA1614,IGDCC4,ATM,ATP1B3,SYNJ2,FMNL3,CCNT1,CBFA2T2,MYOM2,NUMBL,EPS15L1,NRXN3,CLU,DCC,ABCC5,APH1A,RASA4,MRNIP,MTSS1L,ANKMY1,KATNAL1,AMOTL2,MTHFD2,SRCAP,SESN1,AHDC1,CRCP,COPS8,TNRC6A,GNG4,TPPP,KIF3A,KAT7,ATOH8,PADI2,DDX19B,SCRG1,ZNF546,RBPJ,IBA57,ZNF678,KCNH1,IPO5,CCDC80,NUCB1,OGDH,NLE1,RETREG2,TMEM104,SH3TC2,MYH14,GSTCD,KIAA0895L,IL17RB,FAM102A,MAGI3,PEX26,ATF7IP,SCN3B,SON,ACSBG1,SLC37A2,IQCE,NACC2,BHLHB9,TPM3,WBP2,ZNF70,CIAPIN1,SNX27,GAN" MicroRNA hsa-miR-614:mirSVR_highEffct hsa-miR-614:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.13E-21 5.13E-17 1.84E-20 1.70E-19 50 205 "ACADM,ADD3,CC2D2A,OGT,EPB41L5,PHYHD1,TMEFF1,CCKBR,QKI,NRG2,CNRIP1,SEC24C,CTNND2,DCAF4,FBXO25,WDR20,FCF1,MRPL37,TOMM40L,PPP1R1B,FGF13,LUZP2,NCOA7,MAT2A,MYT1,NCAM2,GPR85,PFKFB3,ING3,SUSD4,RBBP6,NUDT11,TCP11L1,DGLUCY,FAM19A1,MTERF2,CPEB4,TNIK,FNDC9,PLCB1,SYP,DMXL2,MTMR14,SMARCAD1,EMSY,CSDE1,PDSS2,RGS7BP,NETO1,SLC4A10" MicroRNA hsa-miR-766-3p:Non-Functional MTI Non-Functional MTI miRTarbase 9.54E-21 5.36E-17 1.92E-20 1.77E-19 92 609 "XKR4,SLC24A4,HACE1,KIAA1324,TXNDC16,TNRC6C,AQP6,CDC14B,ARSE,ZNF555,CBS,SLC16A4,SOCS6,NRXN3,SUSD5,UBXN2A,FAM131B,CENPL,TMEM170A,DNAL1,MED24,TMCC2,MTX3,NR1D2,ABCC5,EBI3,EPB41,EZH1,ANKFY1,TRMO,RAPGEF6,ZNF234,CRCP,GPR75,RAPGEF1,DDX19B,AGBL5,CELF5,SOWAHA,DOCK7,KIAA1755,ZNF678,CREG2,CHST6,MID1,CCDC80,ZC3H12B,SLC11A2,CCSER2,PKM,MTRF1L,TATDN3,STK32A,TMEM145,KLHL11,KLHDC8A,ALG9,ELP2,ATAT1,NCBP3,ZNF331,IL17RB,MAGI3,SEPHS1,RADIL,ZNF667,SNAP25,FAM126B,EMC1,MCF2L2,SSTR2,INKA2,APOM,C3orf70,DNMBP,TMEM151B,ARL10,PARD3,SMUG1,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,TBC1D15,ZNF138,SLC30A4,TRIM16L,WNK2,GAN,SPATA13" MicroRNA "ACCATTT,MIR-522:MSigDB" "ACCATTT,MIR-522:MSigDB" MSigDB 9.56E-21 5.37E-17 1.92E-20 1.77E-19 43 152 "CASKIN1,LRCH2,ARHGAP5,CAPN3,EVI5L,CNTFR,ARMCX2,MYEF2,ZC3H11A,DYRK1A,APH1A,ETV1,SUCO,SYNCRIP,CSPG5,PHYHIPL,KDM2B,GNAO1,GPM6B,HNRNPK,TLX1,DOCK7,MBNL1,LRP1B,HNRNPM,ZC3H12B,NFE2L2,ING3,TNPO2,ZNF532,SALL1,FAM19A1,PPM1E,WDTC1,SP4,NMNAT2,MYCBP2,LMO3,RPGRIP1L,ZNF384,UBE3A,CSDE1,WNK3" MicroRNA hsa-miR-378:PITA hsa-miR-378:PITA_TOP PITA 9.63E-21 5.41E-17 1.94E-20 1.79E-19 40 131 "CAPRIN2,BCL2L2,KSR1,FMNL3,LGI1,AHCTF1,CLOCK,FRMPD4,HDAC4,CALN1,DSCAM,DYRK1A,HIPK3,CELSR3,MED12L,FOXG1,GABRG2,CAB39,GPT2,GRIK2,IL1RAPL1,ZHX1,KIF2A,NEUROD1,NTRK3,PDE4D,PDE1B,VSTM2L,RAP1GDS1,SPIN3,SLC6A1,ZCCHC24,EPB41L3,NSFL1C,SYN2,ANO4,DMXL2,TCF12,ZFPM2,VANGL2" MicroRNA hsa-miR-422a:PITA hsa-miR-422a:PITA_TOP PITA 9.63E-21 5.41E-17 1.94E-20 1.79E-19 40 131 "CAPRIN2,BCL2L2,KSR1,FMNL3,LGI1,AHCTF1,CLOCK,FRMPD4,HDAC4,CALN1,DSCAM,DYRK1A,HIPK3,CELSR3,MED12L,FOXG1,GABRG2,CAB39,GPT2,GRIK2,IL1RAPL1,ZHX1,KIF2A,NEUROD1,NTRK3,PDE4D,PDE1B,VSTM2L,RAP1GDS1,SPIN3,SLC6A1,ZCCHC24,EPB41L3,NSFL1C,SYN2,ANO4,DMXL2,TCF12,ZFPM2,VANGL2" MicroRNA "GAGCCAG,MIR-149:MSigDB" "GAGCCAG,MIR-149:MSigDB" MSigDB 9.98E-21 5.61E-17 2.01E-20 1.85E-19 41 138 "ACLY,ARID1A,ADD1,PCDH19,SEMA4G,ATP2A2,ADGRB1,BCL2L2,SEC24C,RIMS4,LONRF1,KLHL3,DLG4,FAM57B,BAIAP2,AMOTL2,AFF2,B3GAT1,BRPF3,CBX1,KAT7,ICA1,GIT1,MIR4697HG,SLC11A2,NTRK3,PAK3,PDGFRA,ZMAT4,TNFRSF19,SLC6A8,SNCB,IQSEC2,NCDN,PHLDB1,TCF12,FBXL16,VLDLR,SF1,POLR3H,NAV2" MicroRNA hsa-miR-758-3p:TargetScan hsa-miR-758-3p TargetScan 1.02E-20 5.74E-17 2.05E-20 1.89E-19 47 182 "C3orf14,ADD1,RNF150,MAP4K3,CDK13,DACT3,ATP2B2,BMP7,LURAP1,MAP7,REPS2,CFL2,HIPK3,FAM13A,GPR61,ENPP6,GAD2,GFAP,GPR37,GRIK3,RASSF8,DDX19B,ARHGAP36,BACH2,HLF,IL6ST,FGFBP3,MEIS2,MMP16,PAX6,PLCL1,PPP2R2C,PKIA,RELN,GTDC1,GALNT10,HSPA4L,CPEB4,ERC1,CDK19,ADAMTS17,CUX2,PUM2,CBX5,CADM1,FRRS1L,RBFOX3" MicroRNA hsa-miR-549:PITA hsa-miR-549:PITA_TOP PITA 1.05E-20 5.91E-17 2.11E-20 1.95E-19 45 167 "SLC25A25,USP31,NLGN4X,PCDH19,GAS7,ARHGAP5,ZBTB10,LDLRAD4,MAP7,ERC2,KIAA0513,HP1BP3,DLG2,HS3ST4,DMTF1,PDCD6IP,PAN3,ATP8A2,SOX21,MIER3,HMGB1,LIFR,MARK1,MYO5A,PCSK2,CDK14,POU3F2,FBXW7,WLS,SLC30A10,CASC3,SCAF8,SGK1,CPEB3,CHD9,SOX11,SP4,PEG10,SRPK2,POGZ,ATP11A,ZFP91,SMARCAD1,HNRNPA3,VANGL2" MicroRNA hsa-miR-5088-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-20 5.91E-17 2.11E-20 1.95E-19 45 167 "FAM43B,ADCYAP1R1,SORCS2,SPOP,LURAP1,CAMK2G,NEURL1,NUMBL,DNAJB5,LRIG1,PLCXD3,G3BP2,FEM1B,TMTC1,ELAVL3,AMOTL2,TMEM151A,DKK3,WASF3,GPD1,NR3C1,PADI2,EID2B,KCNJ9,MDFI,C10orf105,MYO5A,NPTX2,GPR137C,PDE1B,KANSL1,ZYG11B,DPF2,TMLHE,ELP2,ASIC4,MAPK8IP3,VWCE,RUNDC3B,MEAF6,ZBTB16,TMEM198,CERS6,DPF3,RNF146" MicroRNA hsa-miR-154-5p:TargetScan hsa-miR-154-5p TargetScan 1.09E-20 6.11E-17 2.19E-20 2.01E-19 38 118 "BRAP,MTUS1,CDK13,CAMK2G,DCLK1,FOXN3,CHM,NRXN3,CLTC,GDA,DNAL1,DRP2,DYRK1A,E2F5,LYVE1,LUZP2,KAT7,GUCY1A2,KCNA2,CDH20,MAP4,MYO6,NAP1L1,CNOT4,PCSK5,RAB5B,RIMKLA,SALL1,CSRNP3,FNIP1,CPEB3,PKNOX2,GPRIN3,FBXL16,CADM2,EVI5,FXR1,GAN" MicroRNA "ATTACAT,MIR-380-3P:MSigDB" "ATTACAT,MIR-380-3P:MSigDB" MSigDB 1.10E-20 6.17E-17 2.21E-20 2.03E-19 35 99 "PCDH19,APAF1,APP,NRXN1,DYRK1A,EIF4G2,EPB41L1,FGF12,STAG2,C15orf41,TPPP,IL1RAPL1,ATXN2L,BRINP3,LRRTM3,ITGAV,MBNL1,MEF2C,KITLG,CNOT4,KCNK10,PRKCB,SLC6A15,FIGN,FNDC3A,CPEB4,SNAP25,SP4,ZNF423,LARP4,KLHL4,ZFPM2,TRPS1,FLRT2,PHTF2" MicroRNA "CCAGGGG,MIR-331:MSigDB" "CCAGGGG,MIR-331:MSigDB" MSigDB 1.12E-20 6.28E-17 2.24E-20 2.07E-19 34 93 "AP2A1,SEMA6A,NRP2,KSR1,USP2,TAOK2,DNAJB5,RIMS4,ELMSAN1,FAM78B,PHC2,EGR3,ANKRD13B,BAIAP2,NBEA,GABBR1,CPLX2,GGT7,PLPP7,ATOH8,ATXN2L,MEIS1,MEIS2,NEUROD2,KCTD15,C1orf109,RAB5B,RIC8B,YPEL4,EXOC7,RELL2,NSD2,POLR3H,PRDM8" MicroRNA "AACTGAC,MIR-223:MSigDB" "AACTGAC,MIR-223:MSigDB" MSigDB 1.12E-20 6.28E-17 2.24E-20 2.07E-19 34 93 "PLEKHH1,ALCAM,ZBTB10,ATP2B1,PTBP2,QKI,SLC35F1,SACS,SRGAP3,PHF20L1,F3,OLFM1,FOXO3,RBPJ,IL6ST,INPP5B,STMN1,LMO2,MEF2C,MMP16,NFIA,PDE4D,PDPK1,ANKRD16,MINDY2,WBP1L,FBXW7,SCN3A,SCAF8,SLC8A1,SON,SOX11,EPB41L3,UBTF" MicroRNA hsa-miR-512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-20 6.72E-17 2.40E-20 2.21E-19 62 309 "RNF157,OSBPL8,ZNF578,TAOK1,KIF6,CAPRIN2,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,PRC1,ZBED1,DIS3L,SOCS5,UBXN2A,DNAL1,PLEKHM1,RABGAP1L,SLC12A6,FEM1B,ABI2,IRAK4,BSCL2,TLR7,GTF2IRD2,SEC23B,TRAF3IP2,KIAA1841,SRCAP,MALT1,CRCP,MFSD2A,HAS2,HMGB1,ZNF491,IL6ST,KCNB1,KCND3,GPR155,PFKP,ZNF426,LRP12,OCIAD1,C12orf49,FOXRED2,SBF1,DRAXIN,HSPA4L,SLC8A1,SP2,EMC1,STAC2,WWC1,GPRIN3,ZMAT3,CBX5,PARD3,TPD52,CADM2,WIPF2,MPPE1" MicroRNA hsa-miR-5582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-20 7.51E-17 2.68E-20 2.47E-19 55 248 "XKR4,TMCC3,SORCS1,PTCHD1,ZNF608,PHF12,APP,CDC14B,ARNTL,ZBTB10,ATP2A2,ZNF583,MTMR9,ZNF555,CALM1,CLCN3,CLOCK,RIMS4,CHRDL1,ABI2,STARD3NL,ZNF585B,SUCO,SYNCRIP,APOPT1,UFM1,GABRB1,GABRB3,RNPS1,NUDT21,GRK4,GRIK4,FRMD5,SCIN,IL6R,KLRC3,DDR2,PDE3A,PDGFRA,TNPO2,PKN2,GRAMD1C,DIRAS2,PTPRB,PTPRG,ZYG11B,SETD5,TMLHE,CLUAP1,SMOC1,ZNF106,TJP1,ZIC2,EML6,WNK1" MicroRNA hsa-miR-3175:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-20 7.64E-17 2.73E-20 2.51E-19 58 274 "CPNE2,AP1B1,CASKIN1,HACE1,TAOK1,PDZD4,ARRB1,ASPH,ADGRB2,DIRAS1,CBS,METTL6,ARHGEF2,CLU,RGS6,PHYHIP,PLEKHM1,SEC16A,ABCC5,ING4,ELAVL3,AMOTL2,AFF2,HBS1L,SRCAP,RAPGEF1,SHISA6,SOWAHA,C5orf24,PPM1L,MSI1,SAMD14,PABPC1L2A,NBL1,NDUFA5,GPR173,CCSER2,PLIN1,TNPO2,PTPA,PTPRE,PRRT2,C12orf49,RPS6KA2,CLIP1,CLSTN1,LHFPL4,IQSEC2,CLSTN2,CAMTA2,FAM168A,SLC19A3,HHIP,CBX5,KCTD2,TMPRSS5,UBTF,HNRNPA3" MicroRNA hsa-miR-28-3p:PITA hsa-miR-28-3p:PITA_TOP PITA 1.37E-20 7.68E-17 2.74E-20 2.52E-19 45 168 "ZNF608,CACHD1,PPP4R4,DACT3,CDC42,TAOK2,AHCTF1,CTNND2,LONRF1,MAGI2,G3BP2,DYRK1A,ACSL4,EFEMP1,FOXO3,NPTN,RNF165,ELOVL5,HMGCR,SMAP1,ARHGAP12,NFIX,GPR85,CCSER2,PPP2R5C,UHRF1BP1,USP47,SEMA6D,FNDC3A,ST6GAL1,CNKSR2,SNAP25,ZCCHC24,CDK19,SS18,STAU1,TRIM2,AHCYL2,AKTIP,ZFP91,HEY2,TRPC3,TSC1,ZIC3,GOPC" MicroRNA hsa-miR-630:PITA hsa-miR-630:PITA_TOP PITA 1.43E-20 8.03E-17 2.86E-20 2.64E-19 49 199 "GPR158,LRCH2,ANK3,MAP4K3,APBA2,CADPS,ATP1A1,CDH2,CFL2,QKI,TMEM184B,ANKRD44,ARHGAP24,KLHL3,ELAVL2,FOXG1,BRPF3,SALL3,PCLO,GRIA2,IL1RAPL1,WIF1,KLF12,BACH2,MIER3,HMGCR,ITGAV,KCND2,STXBP5,MEIS2,PCDH9,PDGFRA,PID1,OXR1,RASGRF1,SLC25A36,ATXN1,CHD9,SLITRK3,CPEB4,NPAS3,LMO3,PLCB1,EHBP1,RBFOX2,FLRT2,SLC38A1,PAK5,PHTF2" MicroRNA "GCTTGAA,MIR-498:MSigDB" "GCTTGAA,MIR-498:MSigDB" MSigDB 1.47E-20 8.28E-17 2.95E-20 2.72E-19 36 106 "NCOA1,ATP2B1,C5,CAMK2G,TMEM257,ZIC4,CELF1,FERMT2,EML4,GRIA2,PACSIN2,KLF12,BACH2,AGBL5,DHX35,KCND2,STXBP5,LRP1B,MEIS1,NAP1L3,PDE4B,PIK3R1,PURG,EPB41L4B,PPP3CA,SNRK,ITSN1,FAM214B,PKNOX2,ABTB1,SOX11,ANKRD28,PSD3,DICER1,FLRT2,ST8SIA2" MicroRNA "AGGAAGC,MIR-516-3P:MSigDB" "AGGAAGC,MIR-516-3P:MSigDB" MSigDB 1.47E-20 8.28E-17 2.95E-20 2.72E-19 36 106 "ASIC1,SLITRK1,SORCS1,MTUS1,OGT,CCPG1,CREB5,RIMS2,FAM131B,TM9SF4,PITPNC1,EFNB3,DCTN4,EN2,BAIAP2,GFRA2,HEPN1,GPM6B,CCDC184,ZNF385B,NCAM1,PDE4A,POU3F4,POU6F1,GTDC1,S100B,SLITRK3,SPTB,PLCB1,SYT1,SATB2,TCF12,TNR,OSBP2,ADAMTS9,SOCS4" MicroRNA "GAGACTG,MIR-452:MSigDB" "GAGACTG,MIR-452:MSigDB" MSigDB 1.62E-20 9.12E-17 3.25E-20 2.99E-19 33 88 "AXIN2,OGT,DPP10,DYNLL1,DOCK11,BCL2L2,DCLK1,CCPG1,SLC25A27,DYRK1A,ABCC5,SH3GLB1,SYNCRIP,FOXO3,CELF1,PCDH17,CBX1,ITPKA,MEIS1,OCRL,SLC25A23,PLXNB1,PRRX1,EPB41L4B,NXPH1,BCAS3,GTDC1,FBXO11,SLC6A9,TCF4,TCF12,ZIC1,SNX27" MicroRNA hsa-miR-766:PITA hsa-miR-766:PITA_TOP PITA 1.67E-20 9.37E-17 3.34E-20 3.07E-19 43 154 "SDE2,ASIC1,TMEM132B,TAOK1,LRFN1,CADM3,HAP1,CDH2,DNAJB5,CREB5,OSBPL3,RIMS4,B3GAT3,DLG2,PAN3,SESN1,TNRC6A,GRIA2,MAP4K5,IGF1,IBA57,INSM1,KCND1,ZNF827,MINDY2,PPP3CB,PRKCG,FAM120C,MORC4,SLC1A2,FAM219A,SOX11,LARP4,NCDN,SYNE2,VAMP1,PLCB1,TCF4,RBFOX2,TPM3,ZIC3,CADM2,PPP1R3F" MicroRNA hsa-miR-2276-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-20 9.88E-17 3.52E-20 3.24E-19 48 192 "MARCH4,ARRB1,ATP2B1,CDH8,GPR37L1,STOML1,PNKD,CRY2,RGS6,PITPNM3,UBXN2A,PLCXD3,MYADM,FRMPD4,PHF19,TMEM170A,RUSC2,ST8SIA3,HEYL,OPTN,EMX2,ZNF391,FER,DKK3,MTHFD2,GPR75,GLUL,ZNF638,GRID1,SHISA6,KCNJ9,NODAL,KSR2,OLR1,ZDHHC22,PTPRG,ASIC4,GALNT10,CLUAP1,INKA2,TMEM151B,THRA,PRMT8,KCNK12,SLC30A3,VANGL2,FRMD6,JPH3" MicroRNA hsa-miR-651:PITA hsa-miR-651:PITA_TOP PITA 1.77E-20 9.96E-17 3.54E-20 3.26E-19 45 169 "RALGAPA1,SLITRK1,SEMA6A,ASCL1,SLC4A4,DCAF5,SRSF11,CNTN1,PLCXD3,PUM1,MAGI2,DPYSL2,ELAVL2,SUCO,SESN1,GFRA1,GPR34,FAM19A2,BACH2,IGF1,ZIC5,KCNC2,KCNMA1,LAMP2,NRCAM,PCSK2,PMP22,TRHDE,PPP3CB,MTMR10,SCP2,SLITRK3,CPEB4,CLASP2,CBX5,TSC1,UBE2H,ZBTB38,RNF103,ADAMTS9,NAV3,RGS7BP,FZD3,PAK5,SLC4A10" MicroRNA hsa-miR-125b:mirSVR_highEffct hsa-miR-125b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.77E-20 9.96E-17 3.54E-20 3.26E-19 75 436 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,CNIH2,SHTN1,ARNTL,CDK13,ASPH,ATM,USP2,P2RX6,AIFM1,SULT4A1,LY86,SLC4A8,HINFP,MICAL2,KIAA0586,IST1,ZEB2,RABGAP1L,SPEG,SEMA4D,CGREF1,KIAA1841,RAB30,RABL2A,AGBL5,MSL1,ZNF546,KCNMA1,KCNN2,KLRC2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,PAK3,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,SEC61A2,TMLHE,ATP8B4,COPZ1,BCAN,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,DIP2A,VWA3A,C18orf54,MTMR14,TLR4,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,STMN4,SEMA3B,EPM2A,TIGD6,IFT88,SLC4A10" MicroRNA hsa-miR-134:PITA hsa-miR-134:PITA_TOP PITA 1.79E-20 1.00E-16 3.57E-20 3.29E-19 40 133 "ASIC1,AMPH,NUMB,SLC4A4,ZNF385A,SH2B1,CSNK1G3,ARHGEF4,ARMCX2,CEP170,DLG2,CPEB2,DSCAM,PAN3,BRPF3,SRRM4,MSTN,GNAO1,PRRC2B,EML4,KAT7,HAS2,MAT2A,MBNL1,MYCN,NRCAM,SCN2A,MAGI3,MYT1L,KIF1B,MTCL1,ADGRL3,PSD3,KAT6B,SSBP2,ZNF711,TRIM9,SMARCAD1,SLC30A4,HNRNPA3" MicroRNA hsa-miR-410-3p:Functional MTI Functional MTI miRTarbase 1.99E-20 1.12E-16 3.97E-20 3.66E-19 55 250 "ABCF1,ADD2,ZNF608,MIER1,CA8,SLC24A2,SLC25A27,NSL1,USP6NL,DGKG,CPEB2,MBNL2,CERCAM,RGS17,ACSL4,KIAA1109,POLR1B,ZBED3,TCERG1,COPS8,TPPP,GRID1,BACH2,IGFBP1,SCIN,ITPKB,KLHL23,CCDC80,MYBPC1,NTRK3,OCRL,XRN1,PPP2R5E,ACER3,ZFP30,SLC8A1,ZHX3,AJAP1,PRRC2C,SYP,TRIM2,SIK3,HHIP,HEY1,TPD52,DOK6,RGMB,OSBP2,MEAF6,PMEPA1,MAP3K12,ZXDA,CADM2,CSDE1,STOX2" MicroRNA "ACAGGGT,MIR-10A:MSigDB" "ACAGGGT,MIR-10A:MSigDB" MSigDB 2.12E-20 1.19E-16 4.22E-20 3.89E-19 38 120 "ZNF608,KCTD16,DOCK11,NRP2,MTMR3,BTRC,CAMK2G,NCOR2,ELAVL2,ELAVL3,FLT1,ANKFY1,ZMYND11,TMEM121B,GRM3,RNF165,IL1RAPL1,BACH2,HNRNPK,SMAP1,IGSF1,KCNA6,ARHGAP12,NFIX,PURG,CDIP1,MDGA2,FIGN,KCTD17,RPRD1A,ITSN1,MAPKBP1,SON,NFASC,TRIM2,TMOD1,CSMD1,WNK3" MicroRNA "ACAGGGT,MIR-10B:MSigDB" "ACAGGGT,MIR-10B:MSigDB" MSigDB 2.12E-20 1.19E-16 4.22E-20 3.89E-19 38 120 "ZNF608,KCTD16,DOCK11,NRP2,MTMR3,BTRC,CAMK2G,NCOR2,ELAVL2,ELAVL3,FLT1,ANKFY1,ZMYND11,TMEM121B,GRM3,RNF165,IL1RAPL1,BACH2,HNRNPK,SMAP1,IGSF1,KCNA6,ARHGAP12,NFIX,PURG,CDIP1,MDGA2,FIGN,KCTD17,RPRD1A,ITSN1,MAPKBP1,SON,NFASC,TRIM2,TMOD1,CSMD1,WNK3" MicroRNA hsa-miR-374b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-20 1.35E-16 4.79E-20 4.41E-19 53 234 "ABCF1,XKR4,ADD2,ADD3,GPR158,STX16,NRP2,CA8,SOCS6,NRXN3,ABCG2,SLC25A27,PITPNC1,TMTC1,MBNL2,ACSL4,DLC1,POLR1B,SEC23B,ANKFY1,ZBED3,GABRG2,TNRC6A,LUZP2,NR3C1,BACH2,MIER3,KLRC3,L1CAM,SESN3,CCDC80,MYBPC1,SLC11A2,OCRL,FAT3,EPDR1,MAPK7,ATXN1,BTBD3,SON,STAU1,SYP,TACC1,CAMSAP2,TRIM2,SIK3,HHIP,NR2C2,TRPS1,UBE3A,ZFP37,PMEPA1,SLC38A1" MicroRNA "TCATCTC,MIR-143:MSigDB" "TCATCTC,MIR-143:MSigDB" MSigDB 2.43E-20 1.36E-16 4.83E-20 4.45E-19 40 134 "KCNH8,ADD3,UNC5A,MARCH3,BSN,NEURL1,SRSF11,TAOK2,QKI,AKAP6,CREB5,CSNK1G3,CTNND1,DTNB,PHF20L1,FGF1,UBE2E3,SYT3,AHCYL1,RNF165,MYO6,CNOT4,NTRK2,PC,STRN3,LRP12,SEPT4,MAPK7,SIDT1,ELMOD1,SCAF8,PPM1E,LARP4,SEPT3,PSD3,TPM3,TUBA3FP,KLC2,PHTF2,NETO1" MicroRNA hsa-miR-188-5p:TargetScan hsa-miR-188-5p TargetScan 2.60E-20 1.46E-16 5.19E-20 4.78E-19 44 163 "MAGI1,KMT2C,NIPBL,IGLON5,PCYT1B,HDAC9,DCC,ELMSAN1,GUCD1,NTM,NBEA,NRG3,NEK6,GUCY1A2,FRMD5,KLF12,AGFG1,NKD1,IL6ST,SCRT2,LRRTM3,CDH20,CLVS2,MEF2C,MGAT3,MXI1,PDE4A,RAD51D,ROBO2,FBXW7,RIMKLA,ATXN7,FNIP1,HSPA4L,ABLIM3,KIF1B,NPAS3,ANKRD12,FAM208A,ASXL3,RBFOX2,RICTOR,EVI5,RNF170" MicroRNA hsa-miR-455-5p:TargetScan hsa-miR-455-5p TargetScan 2.71E-20 1.52E-16 5.40E-20 4.97E-19 47 186 "C3orf14,ARID1A,GALNT13,ADD3,KCTD16,PHF12,CDK13,DCAF5,LDLRAD4,CACNB4,CAST,FOXN3,NRXN1,NMT2,CLOCK,RIMS4,PLCXD3,CTNND1,FRMPD4,MFAP3L,DYRK1A,EBF1,ABI2,PLXNC1,EPHA5,ERBB4,INPP5K,KIF3A,RNF165,FICD,HAS2,FRMD5,KLHL23,LAYN,PDGFRA,CDK14,NXPH1,FIGN,CPEB3,R3HDM2,EPN2,CPEB4,KIF1B,NPAS3,CLSTN2,DOCK9,CDH22" MicroRNA hsa-miR-539-5p:Functional MTI Functional MTI miRTarbase 2.81E-20 1.58E-16 5.59E-20 5.15E-19 50 210 "RNF157,SPOP,TNRC6C,SFMBT2,DDX3Y,BACH1,CALM1,CDC27,CLCN3,HS3ST5,OSBPL3,SIPA1L1,PDE4DIP,RUBCN,CTIF,DPYSL2,ELAVL2,MSANTD4,HRASLS5,CAB39,WASF3,RNPS1,IL1RAPL1,MSL1,IGF1,LAMA2,XRRA1,SESN3,CCDC80,ADAM22,C10orf105,CNOT4,NUCB2,OPHN1,GPR137C,ZIK1,PTPRN2,SETD5,FAM161B,TRA2B,KIF21A,SOX11,ACSL6,TCF7L2,ZEB1,ZMAT3,BCL2L13,MTCH1,SF1,DNALI1" MicroRNA hsa-miR-6867-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-20 1.58E-16 5.59E-20 5.15E-19 50 210 "ASPA,ZNF582,BACH1,CBS,CCNT1,CDH8,QKI,PITPNM3,CYBB,SPATA2,SMG7,PHF20L1,EMX2,EPB41L1,SRARP,TACC2,RAPGEF6,NCKAP1,SRRM4,GJB1,ZNF638,KIAA1958,GRID1,RFFL,PADI2,SHISA6,KCNQ3,STMN1,LSAMP,MBNL1,ZDHHC22,GNG2,SDK2,MTMR10,PTPRG,ZFP1,ZNF415,ZCCHC24,CLUAP1,LRRC4,DIP2A,ACSBG1,TMEM178B,ACSL6,RUNDC3B,SSBP2,TSPAN11,ZNF781,ZNF138,URM1" MicroRNA hsa-miR-6747-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.86E-20 1.61E-16 5.70E-20 5.25E-19 81 501 "AS3MT,RNF157,ADD1,RNF150,ESYT2,TAOK1,ABCD2,CDC14B,SLC7A14,ARSE,SLC4A4,CACNA1A,STOML1,QKI,RTTN,CREM,HINFP,CSNK1E,PITPNM3,KIAA0408,DNAL1,RABGAP1L,KBTBD11,CNNM1,MRNIP,RGS17,PLEKHO1,SLC43A2,TLR7,FKTN,FDFT1,FOXO3,PDLIM5,TMEM151A,FAXC,CRCP,RAB40B,CNDP1,GRK4,PTPRT,KIF3A,RNF165,HMGB1,ZDHHC15,ATCAY,EID2B,IL6R,NCOA7,LSAMP,CHST6,ALDH1L2,PBX1,MTRF1L,APTX,TMEM231,ZNF844,NWD1,GTDC1,DCUN1D2,PGBD4,RXRA,SCN2B,ZFP30,PEX26,ZNF667,CLUAP1,ARHGAP26,AGTPBP1,GPRIN3,ZNF106,ARL10,ERCC6L2,PARD3,TPM4,RPL7L1,AGMO,ZNF70,LMAN2L,WIPF2,MPPE1,VANGL2" MicroRNA hsa-miR-3926:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.89E-20 1.62E-16 5.74E-20 5.29E-19 61 305 "PLEKHH1,KIAA1324,GOLGA7B,SEMA7A,GPAM,PDXK,BACH1,CBS,CCNT1,RAB3C,LRIG1,CTH,GREB1,YTHDC1,CEP170,SIDT2,MRO,COQ7,ZNF549,POLR1B,GATM,GLUL,LUZP2,ADAMTS8,RNF165,HLF,ZNF678,MAG,MAPT,SAMD5,PABPC1L2A,SFR1,SLC11A2,STRN3,TNPO2,MAPK8,PTPRB,CEP97,MRPS18A,SNX22,RTKN,FOXRED2,HOGA1,MAGI3,URGCP,PREX2,SOX5,DDN,NEK4,SYT11,TBCEL,USP22,ZMAT3,TPM3,ZNF610,VLDLR,TBC1D15,ZNF17,ZNF70,TMEM237,RGMA" MicroRNA hsa-miR-3942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.28E-20 1.84E-16 6.52E-20 6.00E-19 40 135 "SDE2,BARD1,VXN,MATR3,FAM107B,SH3GLB1,KATNAL1,CAMSAP1,SUCO,UFM1,SRRM4,COPS8,TNRC6A,GNAL,ZBTB49,BACH2,KIAA1755,KCNN3,CREG2,KCTD6,SESN3,NUCB1,OLR1,PCSK1,PDPK1,EPB41L4B,MINDY2,BDNF-AS,SH3TC2,CCDC25,SGK1,ZFP30,NBPF1,TRIM67,FAM126B,TROVE2,NEK4,FGD4,KCTD2,ATP6V0E2" MicroRNA hsa-miR-3148:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.29E-20 1.85E-16 6.53E-20 6.02E-19 54 244 "AXIN2,MTA3,ZBTB10,CALM1,CDC25B,CDC27,HAPLN1,APPL1,CTNND1,KIAA0513,LONRF1,SPATA2,ABCC9,PLEKHA1,EN2,TUBA1B,DLC1,TMEM164,GABRB1,MALT1,CRCP,GPR75,TNRC6A,PRUNE2,DIPK1C,STMN1,MDM4,SESN3,ADAM22,NASP,NCAM1,PDE4D,ZYG11B,PRRT2,SLC25A36,SOX6,CPEB3,BCAN,SLC6A8,SLC8A1,LIMCH1,TAB2,NXT2,ZMAT3,NACC2,ZFP91,RBFOX2,TPM3,TPM4,ZKSCAN5,LYPD6,SLC38A1,ITM2C,RTN4" MicroRNA hsa-miR-411-5p.2:TargetScan hsa-miR-411-5p.2 TargetScan 3.39E-20 1.91E-16 6.74E-20 6.21E-19 35 102 "GALNT13,MTA3,CACHD1,ARHGAP5,LDLRAD4,RUNX1T1,CDH2,DCLK1,RAB3C,AKAP5,CTNND1,CCDC144A,EBF1,EGFR,MBNL2,ERBB4,CAMKK2,CELF1,RAPGEF6,IQGAP2,GK,HLF,LIFR,MATN3,GPR173,LRP12,DCHS2,CSRNP3,FNIP1,PPP1R9A,CPEB4,NKAIN2,DAAM2,CLIP2,ELFN1" MicroRNA hsa-miR-1247:mirSVR_lowEffct hsa-miR-1247:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 3.43E-20 1.93E-16 6.81E-20 6.27E-19 61 306 "AP2A2,DISP3,SHROOM2,CAPRIN2,SNAI3-AS1,NRP2,TRIM41,BRSK2,CBS,CD81,CHRNA4,ANKRD35,PHACTR3,DCAF4,KIF26A,DNM2,TENM1,RASL12,REEP2,WAC,TAOK3,CAP2,AGAP2,RASL10A,PRELID3A,BRSK1,FAM120B,RND1,GRIA1,ADAMTS13,GRIN1,HTR5A,RTL5,PDE2A,CDIP1,RGS12,STX1B,ZNF331,WDR37,EPN2,SLC6A7,SLC20A2,CPEB4,SNRPN,DOP1A,LRRC4,AJAP1,TMEM150C,ADGRL3,ZNF346,PRMT8,NEIL2,TTTY15,HSPBP1,KLC2,ZNF708,NDRG4,MEIS3,RNF103,SEMA3B,EPM2A" MicroRNA hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 3.48E-20 1.95E-16 6.91E-20 6.36E-19 60 297 "FAM43B,ARID1A,ADORA3,ANXA7,CACHD1,ADGRB2,CBS,SCARB1,ZBED1,IGDCC3,CS,PUM1,KIAA0408,MYADM,DNAL1,DBT,RUSC2,TOM1,DYRK1A,USPL1,SRRM1,TUBA1B,RACK1,ATP5PD,USP16,ARFGAP2,ZMYND11,TMEM8B,PCDH11X,TUBA1C,ATXN2L,ELOVL5,ZIC5,IPO5,CHIC1,MKLN1,NEUROD2,NFIX,OPRL1,PALM,PKD1,PMS2,DEF8,RAD51D,ARHGEF10L,TMCC1,TRERF1,SEPT8,GANAB,TCF7L2,CRTC1,WBP2,STXBP4,UGT8,MGAT5B,NSD2,POLR3H,AMZ1,TUBA1A,ITM2C" MicroRNA hsa-let-7i-5p:Functional MTI Functional MTI miRTarbase 3.59E-20 2.02E-16 7.13E-20 6.57E-19 64 334 "FZD9,MTUS1,ZNF578,EP400,AQP6,IGDCC4,ASCL1,BACH1,FMNL3,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,PLEKHO1,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,SALL3,DISC1,GATM,COPS8,POLL,FUT10,RABL2A,IGF1,IL6R,KPNA5,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,PIK3C2A,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,TGFBR3,CBX5,TLR4,RBFOX2,TUBB2A,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-1224-5p:PITA hsa-miR-1224-5p:PITA_TOP PITA 4.06E-20 2.28E-16 8.05E-20 7.41E-19 38 122 "MAP4K3,DDX3Y,THSD7A,TRIM41,RUNX1T1,FMNL3,DCLK1,CRY2,SV2A,GRIN3A,DYRK1A,RBM12,CPLX2,GPD1,ATF7,ZHX1,GABARAPL2,USP54,KCNA1,CHIC1,KITLG,NOVA1,PCMT1,MAPK10,GTDC1,SATB1,SCP2,ITSN1,NFASC,ZFP91,TRPS1,FNDC5,TUBB2A,EIF4ENIF1,UCHL1,DPF3,RNF146,SENP7" MicroRNA hsa-miR-3196:mirSVR_highEffct hsa-miR-3196:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.06E-20 2.28E-16 8.05E-20 7.41E-19 38 122 "SLITRK1,SUGT1P4-STRA6LP-CCDC180,PPFIA3,ZSCAN18,SEC11C,DDR1,INA,DLGAP3,KIAA1549L,CLTA,CABP1,CYBB,GTF2IRD2,PSD2,ARHGAP36,MEIS1,NKX2-2,NPTX2,ZNF827,NALCN,EXOSC10,RFX4,ST3GAL3,LGI3,SLC22A4,SMARCC2,TNIK,KAZN,TAF6,PRRT1,TRH,FNDC5,NSD2,ATP6V0E2,ANKS1B,DHX33,CASC15,ADAMTS10" MicroRNA hsa-miR-581:PITA hsa-miR-581:PITA_TOP PITA 4.11E-20 2.31E-16 8.14E-20 7.50E-19 42 150 "SORCS1,LRRC7,DPP10,MAP4K3,APP,STX16,LDLRAD4,CACNA1A,VSTM2A,DLGAP2,NRXN3,ARHGEF6,AKAP6,TENM4,USP6NL,DSCAM,DYRK1A,FAM135B,TENM1,RCAN2,FOXO3,TMEM151A,GABRB3,PCDH17,STON1,AGFG1,KCNA1,KITLG,NFIX,PCDH9,DIRAS2,PTPRD,LGR4,SUPT20H,FBXO11,SON,SOX11,SP4,PEG10,CDK19,FLRT2,CERS6" MicroRNA hsa-miR-4731-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.85E-20 2.73E-16 9.62E-20 8.86E-19 68 374 "ADD1,PNMA8B,ZNF578,TAOK1,AMH,KIF6,PPFIA4,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,METTL6,NEURL1,DIS3L,PLAA,CLU,BTF3L4,IGDCC3,RGS6,SOCS5,UBXN2A,MYADM,DNAL1,RABGAP1L,SLC12A6,ABI2,IRAK4,MRPL37,TLR7,TUBB4A,GTF2IRD2,ZBED3,TRAF3IP2,KIAA1841,CRCP,GRIK3,MFSD2A,HAS2,HMGB1,ZNF491,KCND3,KCNH2,CYP27C1,GPR155,MBD1,CHST6,PKM,SPATA6,OCIAD1,RAB5B,C12orf49,FOXRED2,SBF1,DRAXIN,GALNT10,HSPA4L,SP2,EMC1,RAP1GAP2,WWC1,GPRIN3,ZMAT3,THRA,CBX5,PARD3,ZNF708,MPPE1" MicroRNA hsa-miR-509-3p:PITA hsa-miR-509-3p:PITA_TOP PITA 4.89E-20 2.75E-16 9.68E-20 8.91E-19 35 103 "GPR158,SYNJ1,MTMR3,CACNB4,CAMK2A,NR1D2,NRN1,TAOK3,GAB1,AHCYL1,GNAO1,GPD2,INSM1,LRRTM1,KCNMA1,MAT2A,ENPP2,PLP1,PPP2R5C,PKIA,PTPN13,USP47,WLS,RXRA,ATXN1,ATXN7,SCN2B,SFPQ,PPP1R9A,NECAB1,ATP11A,SMG6,CSMD1,ZIC3,WNK1" MicroRNA "GGTGTGT,MIR-329:MSigDB" "GGTGTGT,MIR-329:MSigDB" MSigDB 4.89E-20 2.75E-16 9.68E-20 8.91E-19 35 103 "BCL7A,PTBP2,KRIT1,CLTB,CRMP1,CSNK1G3,DAPK1,SRGAP3,SUGP2,EIF4G1,RNF165,KLF12,IL6ST,MEF2C,RTL5,MYT1,PDE4D,ZNF655,PRKACB,SLC22A23,ZFHX4,RXRG,ATXN1,CLSTN1,FAM219A,NFASC,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,CLDND1,NAV3" MicroRNA hsa-miR-920:PITA hsa-miR-920:PITA_TOP PITA 4.89E-20 2.75E-16 9.68E-20 8.91E-19 35 103 "ASIC1,SEMA4G,ADGRB1,BCL2L2,CACNA1A,CALB2,TAOK2,NIPBL,RHOBTB1,ELN,ANKRD13B,SRRM1,AGAP3,GAB1,TTBK1,RAPGEF1,GRIN2D,KAT7,BACH2,CNOT4,NUMA1,NLGN3,ANKRD16,MED1,SH3TC2,ATXN1,MYO18A,SLC1A3,TET1,GKAP1,SP2,TCF7,THRA,ZNF384,KAT6A" MicroRNA hsa-miR-640:PITA hsa-miR-640:PITA_TOP PITA 4.90E-20 2.75E-16 9.70E-20 8.94E-19 45 173 "ZNF608,INTS2,GPRASP2,ATP2B1,JAZF1,FOXN3,CLTC,CNR1,ABI3BP,TIAM2,EIF5,EXTL2,DLC1,AFF2,OGA,PCLO,STMN2,GRIK2,CDH20,MBNL1,KITLG,NELL1,NOVA1,PRRX1,PKN2,ARID4A,PBRM1,ATXN7,SCP2,SH3GL2,TMCC1,FAM126B,SOX5,POGZ,CAMTA1,WSCD1,SATB2,DICER1,ZFP91,TPM3,VLDLR,PCDH20,NAV3,FZD3,HNRNPA3" MicroRNA hsa-miR-501-5p:Functional MTI Functional MTI miRTarbase 4.94E-20 2.77E-16 9.77E-20 9.00E-19 43 158 "SLC25A25,MTUS1,TAOK1,TRMT9B,ASGR1,SCARB1,LONRF2,HINFP,RGS6,PPP1R16B,C2CD2L,NTM,FSD1L,ZNF585B,GORAB,ST6GALNAC3,HHIPL1,BRPF3,MTHFD2,FAXC,OS9,PRRC2B,GPM6B,RNF165,HAS2,HSP90AA1,NKD1,KCNN3,PLIN1,PXK,ZMAT4,PGBD4,SLC1A2,SLC8A1,MYT1L,C11orf87,ELOVL4,TACC1,SIK3,NR2C2,FRRS1L,NELFE,VANGL2" MicroRNA hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 5.27E-20 2.96E-16 1.04E-19 9.61E-19 55 255 "EMILIN3,OSBPL8,ALK,CNTNAP1,TNRC6C,PRX,PLA2G4C,UBXN2A,ARHGAP32,CALN1,NR1D2,FRY,PHF20L1,EGFR,IRAK4,FABP7,ACSL4,RACK1,POLK,B3GAT1,CHL1,NCKAP1,GK,EML4,TJAP1,KCNJ9,STMN1,LIFR,LIG4,NAP1L1,CCSER2,FAT3,MTMR10,RAB5B,SH3TC2,FAT4,KLHL11,SETD5,GSTCD,YY1AP1,LGR4,SOX6,DOCK10,FAM81A,SOX5,SAMSN1,STAU1,ANKRD28,CAMSAP2,CRTC1,SIRT1,ZNF711,PARP11,RTN4,FXR1" MicroRNA hsa-miR-1263:PITA hsa-miR-1263:PITA_TOP PITA 5.33E-20 2.99E-16 1.05E-19 9.71E-19 34 97 "ADRA1B,MAP4K3,ARHGAP5,CADPS,NCOA1,STX16,BCL7A,CACNA1A,CREB5,PLCXD3,LYPD1,SNAP91,EFNA3,YAF2,MTHFD2,LRRTM1,KCNJ10,MAT2A,MID1,NEUROD1,PCDH9,MAPK10,PPM1E,FBXO11,RUFY2,PHLDB1,PRRC2C,ARHGEF9,NSD1,DICER1,TP53BP2,BEST1,TRIM9,HNRNPA3" MicroRNA hsa-miR-629-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.62E-20 3.16E-16 1.11E-19 1.02E-18 48 197 "GPR158,TNRC6C,SEMA4G,ASPA,ATP1B3,BACH1,CBS,NEURL1,CDH8,RGS6,PITPNM3,SPATA2,PHF20L1,EMX2,EPB41L1,RAPGEF6,NCKAP1,ZNF638,KIAA1958,RABL2A,PADI2,NEGR1,CELF5,KCNQ3,STMN1,LSAMP,MBNL1,ZDHHC22,GNG2,ZNF426,SDK2,EPDR1,PTPRB,SLIT1,ZFP1,ZCCHC24,UHRF1BP1L,GANAB,ACSL6,RUNDC3B,SSBP2,BCL2L13,TSPAN11,ZNF781,ZNF138,URM1,WNK2,ZNF248" MicroRNA hsa-miR-620:PITA hsa-miR-620:PITA_TOP PITA 5.68E-20 3.19E-16 1.12E-19 1.03E-18 44 166 "HECW2,SEMA6A,OGT,MARK4,LRBA,LGI1,LHX2,SLC35F1,RIMS4,IST1,HS3ST4,CPEB2,DYRK1A,EDIL3,PHC2,APH1A,MBNL2,RGS17,ELN,KHDRBS3,PCLO,CIT,KIAA1755,MEF2C,KITLG,SCAMP5,CNTN3,OLA1,HMGCLL1,EPB41L4B,NXPH1,GTDC1,HECW1,LMO3,STAU1,RGL1,PLCB1,UNC5D,WWC1,TBX15,DICER1,TJP1,RIMBP2,ST8SIA2" MicroRNA hsa-miR-1270:PITA hsa-miR-1270:PITA_TOP PITA 5.68E-20 3.19E-16 1.12E-19 1.03E-18 44 166 "HECW2,SEMA6A,OGT,MARK4,LRBA,LGI1,LHX2,SLC35F1,RIMS4,IST1,HS3ST4,CPEB2,DYRK1A,EDIL3,PHC2,APH1A,MBNL2,RGS17,ELN,KHDRBS3,PCLO,CIT,KIAA1755,MEF2C,KITLG,SCAMP5,CNTN3,OLA1,HMGCLL1,EPB41L4B,NXPH1,GTDC1,HECW1,LMO3,STAU1,RGL1,PLCB1,UNC5D,WWC1,TBX15,DICER1,TJP1,RIMBP2,ST8SIA2" MicroRNA hsa-miR-768-5p:PITA hsa-miR-768-5p:PITA_TOP PITA 5.88E-20 3.31E-16 1.16E-19 1.07E-18 39 130 "LRFN1,SYNJ1,VXN,SRSF11,FOXN3,CLCN4,CNTFR,FAM171B,YTHDC1,CHRDL1,FAM57B,PHC2,EPB41,LYVE1,GK,EML4,FICD,GUCY1A2,KLF12,ZIC5,KITLG,MITF,MYBPC1,NRCAM,NTRK3,PDE1B,PLCL1,PMP22,PTK2,RAB5B,DPF2,ZFHX4,WLS,SYT1,WASHC4,FRYL,TRPC3,SMARCAD1,KAT6A" MicroRNA hsa-miR-921:PITA hsa-miR-921:PITA_TOP PITA 6.06E-20 3.40E-16 1.20E-19 1.10E-18 36 110 "ADD3,ADRB2,RTL9,MAP4K3,ADGRB3,CACNA2D2,FOXN3,KMT2C,BTF3L4,LRRC3B,NRSN1,TMEM121B,ADAMTS6,HAS2,MIER3,HSF2,CHIC1,MEIS2,POU3F2,KANSL1,TMEM260,NCBP3,SOX6,CCDC88A,SNCA,FAM219A,ZCCHC24,CDK19,LMO3,NKAIN2,ADGRL3,RBFOX2,NR2C2,CADM1,HNRNPA3,VANGL2" MicroRNA hsa-miR-450a:mirSVR_highEffct hsa-miR-450a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.51E-20 3.66E-16 1.29E-19 1.18E-18 62 319 "GALNT16,KIAA1211,ZNF608,SNX32,KIAA1324,VAT1L,TTLL9,RAB33A,AKAP7,RTTN,MYRIP,SLC35F1,CPS1,RIPOR2,DGKB,HEPH,PLPPR4,EGFR,KMT5B,ELAVL2,EPHB1,F8,ST3GAL6,SMC2,ADGRA3,GPM6A,GRM7,LINC01551,LIX1,CYP27C1,KTN1,PAXBP1,MATN3,MEIS1,MITF,MMP16,COL28A1,CTNNA3,PAK3,PCSK1,KANSL1,PTN,ZNF615,CRTAC1,ATP8B4,RPS20,FNIP1,ST3GAL3,ZNF365,BTBD3,ZNF667,UNC80,SAMSN1,AJAP1,PCDHGB7,DCBLD1,SLAIN1,CLDND1,ELFN1,ZBTB16,SMARCAD1,TRAM2-AS1" MicroRNA "GCACCTT,MIR-18A:MSigDB" "GCACCTT,MIR-18A:MSigDB" MSigDB 7.01E-20 3.94E-16 1.38E-19 1.27E-18 35 104 "ADD3,ALCAM,DPP10,NCOA1,CDC42,SOCS5,PHF19,PHF20L1,EPB41L1,SUCO,GAB1,GLRB,ADAMTS13,NR3C1,ATXN2L,HSF2,IGF1,KIT,MDGA1,PACSIN1,PRKACB,FAM192A,ATXN1,CCDC88A,SON,FNBP1,TEX2,CDK19,C11orf87,CLASP2,MESP1,CAMSAP2,TRIM2,PSD3,PARP6" MicroRNA "GCACCTT,MIR-18B:MSigDB" "GCACCTT,MIR-18B:MSigDB" MSigDB 7.01E-20 3.94E-16 1.38E-19 1.27E-18 35 104 "ADD3,ALCAM,DPP10,NCOA1,CDC42,SOCS5,PHF19,PHF20L1,EPB41L1,SUCO,GAB1,GLRB,ADAMTS13,NR3C1,ATXN2L,HSF2,IGF1,KIT,MDGA1,PACSIN1,PRKACB,FAM192A,ATXN1,CCDC88A,SON,FNBP1,TEX2,CDK19,C11orf87,CLASP2,MESP1,CAMSAP2,TRIM2,PSD3,PARP6" MicroRNA hsa-miR-670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.06E-20 3.97E-16 1.39E-19 1.28E-18 48 198 "C3orf14,XKR4,SLC25A25,GRAMD1B,C1QTNF3,TNRC6C,APP,SLC7A14,ATP2B3,LDHD,LDLRAD4,RUNX1T1,LONRF2,SLC22A6,IGDCC3,PDE4DIP,PLCXD3,TOMM20,USP3,DPYSL2,EDN1,TMTC1,C8orf37,ERBB2,MRPL37,SCML2,GABRA5,TXNL4A,GRID1,GRIK3,PTGDR2,HMGB1,MAT2A,MBNL1,MID1,ZNF844,ELP2,NLGN1,SLC2A5,SLIT1,ACSL6,AHCYL2,TGFBR3,ZNF138,TFIP11,FAM13C,JMJD1C,FRMD6" MicroRNA hsa-miR-512-5p:PITA hsa-miR-512-5p:PITA_TOP PITA 7.12E-20 4.00E-16 1.40E-19 1.29E-18 42 152 "TAOK1,BCL2L2,LURAP1,SPAG9,FMNL3,DLGAP2,CHRM1,GDA,CNTNAP2,KIAA0753,SMG7,SNAP91,MTX3,DMD,DYRK1A,ABI2,EMX2,PCDH17,GRIN1,GRM3,KCNA6,KCND2,MAP2,MN1,NEXMIF,NFIX,PCSK1,PIK3R1,RASGEF1B,DBX2,COPZ1,CHD9,RIMS1,SRPK2,SYT4,FBXW11,TCF4,ZFPM2,FAM155A,WIPF2,PDSS2,PHTF2" MicroRNA hsa-miR-526b:PITA hsa-miR-526b:PITA_TOP PITA 7.12E-20 4.00E-16 1.40E-19 1.29E-18 42 152 "MTUS1,ZBTB10,SLC4A4,MTMR9,CACNA1D,CLIP3,KIAA0408,FRMPD4,ALKBH8,POM121,CPEB2,DMTN,EPHB1,NRN1,DLC1,OGA,GABRG2,DNER,TDRKH,ZHX1,FRMD3,IGF1,C5orf24,KTN1,MAP2,MKLN1,GPR137C,ZNF827,XRN1,STRN3,RELN,SLC6A15,ZFHX4,ROBO1,RIMKLA,PPP1R9A,ARX,ACSL6,HHIP,ZFP91,PRDM10,SOCS4" MicroRNA hsa-miR-483-3p.2:TargetScan hsa-miR-483-3p.2 TargetScan 7.66E-20 4.30E-16 1.51E-19 1.39E-18 38 124 "OGT,KSR1,CAMK2G,CANX,FMNL3,CCNT1,AIFM1,RCHY1,ACBD5,NRG2,IP6K1,DCT,MFAP3L,PHF20L1,ERBB4,ANKFY1,ATP2C1,GABBR1,ATP8A2,PRUNE2,IGF1,CAMK2N2,MDM4,MITF,AFF1,MED1,RAB5B,RPE,EPHA10,ACER3,SATB1,FAM126B,KIF21B,CLSTN2,GANAB,EXOC7,HHIP,GAN" MicroRNA "ACACTAC,MIR-142-3P:MSigDB" "ACACTAC,MIR-142-3P:MSigDB" MSigDB 7.66E-20 4.30E-16 1.51E-19 1.39E-18 38 124 "FMNL2,TAOK1,ANK3,PPFIA1,APC,ARNTL,ATP2A2,BACH1,CFL2,CLTA,HECTD1,PUM1,COPS7A,CPEB2,ACSL4,SUCO,AFF2,EML4,KAT7,PSIP1,BACH2,HMGB1,ITGAV,AFF1,PDE4B,STRN3,ATG16L1,SGK1,FNDC3A,BTBD7,ATF7IP,SOX11,TAB2,STAU1,SYPL1,TRPS1,RICTOR,XPO1" MicroRNA hsa-miR-525-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.95E-20 4.47E-16 1.56E-19 1.44E-18 40 138 "PCDH19,TAOK1,SEMA7A,APBB2,ZNF582,CDC25B,NRXN3,CLU,BTF3L4,C2CD2L,RASGRP1,REEP2,FOXO3,AFF2,CELF1,ZNF274,GPM6B,KCNH1,MPP2,ZNF827,ZNF426,PPP2R5E,PRKCB,MDGA2,SETD5,ELP2,RXRA,NCBP3,HES6,SGK1,PEX26,ATF7IP,SON,ARHGAP26,TACC1,AGMO,CSDE1,CIAPIN1,URM1,NELFE" MicroRNA hsa-miR-1206:PITA hsa-miR-1206:PITA_TOP PITA 8.05E-20 4.52E-16 1.58E-19 1.46E-18 45 175 "TAOK1,ALCAM,USP37,SHTN1,TMEFF1,ARHGAP5,USP6,DGKI,KCNAB3,CDH10,QKI,SOCS5,ST18,FRMPD4,CDON,CPEB2,TENM1,USPL1,SEC24B,PRKAG2,CAMKK2,GATM,PPARGC1A,HTATSF1,BRINP3,ITGAV,KCNB1,KCND2,LRP1B,KITLG,MITF,NOVA1,GPR88,PIK3C2A,PPP3CA,FIGN,ATXN2,SCN3A,FNIP1,SOX6,ANKRD12,CAMTA1,CAMSAP2,TCF4,FRYL" MicroRNA hsa-miR-650:Functional MTI Functional MTI miRTarbase 8.16E-20 4.59E-16 1.61E-19 1.48E-18 73 427 "ABCF1,NDRG2,PLEKHG5,ADD2,PNMA8B,TRMT9B,KIF6,CPNE5,ARHGDIA,ATM,DDR1,CANX,CLU,LETMD1,CRY2,NCOR2,IPCEF1,RASSF2,LIN54,TMEM170A,DNAL1,SGSM2,SEC16A,RASA4,ING4,MRNIP,ANKMY1,KATNAL1,MRVI1,TRMO,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,KIF3A,DDX19B,SCRG1,IBA57,KLHL23,SAMD5,CCDC80,NBL1,NUCB1,PDGFRA,TMOD2,PLEC,PLXNB1,RETREG2,ZNF793,SETD5,NCBP3,SLC30A10,FAM102A,MAGI3,TRIM67,ATF7IP,ERC1,PEG10,IQSEC2,ZSCAN29,ACSBG1,USP22,PPIL6,SSBP2,ZNF70,INTS3" MicroRNA hsa-miR-296-3p:Functional MTI Functional MTI miRTarbase 9.34E-20 5.25E-16 1.84E-19 1.69E-18 55 258 "ARID1A,MTA3,PITPNM2,SHROOM2,CA8,SEPT7,CDC25B,ZBED1,SLC22A6,SMARCAL1,PUM1,CX3CR1,PYGO1,DCAF8,ADGRV1,TUBA1B,RACK1,SEC24B,FGFR1,TRMO,SRCAP,CRCP,TCERG1,GLUL,PRRC2B,CCDC184,TUBA1C,KCNH1,LSAMP,MPP2,PKM,FAT3,POLG,PPP1R1A,MAPK7,ZNF844,ZFHX4,FBXW7,ATAT1,SATB1,SBF1,ITSN1,FAM102A,ZNF667,ZNF621,DICER1,FBXL16,TSC2,UBC,ZNF781,ZNF138,ITM2C,KAT6A,SSPN,GAN" MicroRNA hsa-miR-330-3p:Functional MTI Functional MTI miRTarbase 1.01E-19 5.68E-16 1.99E-19 1.83E-18 41 146 "RNF150,MTA3,BCAS1,CDC42,SLIT2,CLTB,SPATA2,CASP8AP2,EFNA3,RASA4,TOMM40L,CELF1,GUCY1A2,SYNPO,NEGR1,DHX35,TJAP1,METTL21A,ARHGAP12,MSI1,BLOC1S2,NTRK3,PCMT1,PFKFB3,PKM,CRLS1,PLEKHB2,ROBO1,SH3GL2,FAM126B,SP4,NXT2,KIAA0930,SLC19A3,TGFBR3,THRA,LRRC8A,RIMBP2,PRMT8,ZBTB16,URM1" MicroRNA hsa-miR-9-5p:Functional MTI Functional MTI miRTarbase 1.02E-19 5.70E-16 1.99E-19 1.84E-18 65 350 "TTYH1,TAOK1,ALCAM,APBB2,KIF1A,NIPA1,CA8,SPAG9,MAP7,PLEKHB1,SUMF2,TBPL1,NCOR2,ARHGEF10,SOCS5,HDAC4,MTX3,ATL1,OPTN,EN2,TESK2,FOXO3,ANKFY1,NBEA,ZBED3,CAMKK2,MTHFD2,RASSF8,LRRTM1,JAK1,STMN1,MDM4,MN1,MSR1,NF1,NKX2-2,NTRK3,PRTG,PRRX1,PPARA,PTX3,ZMAT4,PCMTD2,ATXN7,FERMT1,SLC2A5,CPEB4,FNBP1,NMNAT2,EMC1,KIF1B,POGZ,STAU1,SYNE2,SYPL1,TAL1,SYNE1,SLC19A3,DICER1,SIRT1,ITGB3BP,NR2E1,RBFOX2,SLC30A4,RNF146" MicroRNA hsa-miR-1254:PITA hsa-miR-1254:PITA_TOP PITA 1.08E-19 6.05E-16 2.11E-19 1.95E-18 39 132 "PCDH19,ANK1,CAPRIN2,ATP2B2,CADM3,HAP1,CCPG1,NIPBL,AHCTF1,SLC35F1,FRMPD4,IP6K1,SORBS3,TMEM35A,ZIC4,TOX3,SCAMP5,PABPC1L2A,NOVA1,PKM,FAT3,PPP3CB,ARID4A,FEZF2,CLIP1,STX1B,SCN2B,MYO18A,HECW1,GSE1,MTCL1,SATB2,ENHO,MEAF6,SF1,ZIC1,MEIS3,URM1,FZD3" MicroRNA hsa-miR-651-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-19 6.68E-16 2.33E-19 2.15E-18 51 225 "OSBPL6,OGT,PDXK,IGDCC4,ATP2A2,FOXK1,BTF3L4,CREB5,CRY2,SOCS5,CTNND1,PUM1,DCAF8,LONRF1,SPATA2,CHRDL1,SEZ6,TVP23A,CAB39,PRRC2B,EML4,C5orf24,TTYH2,SYT9,MKLN1,SESN3,CCDC80,NCAM1,PDPK1,PTPRB,ZYG11B,AMER2,SOX6,LGI3,COA1,TMCC1,IQSEC2,TAB2,SEPT3,SLC44A1,RBFOX2,TPM4,UBC,AMOT,CLDND1,SF1,ZXDA,CSDE1,XKR7,ITM2C,SPATA13" MicroRNA hsa-miR-942-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.38E-19 7.77E-16 2.72E-19 2.50E-18 48 201 "FAM43B,GALNT13,ADD1,NLGN4X,SPOP,ANK1,ASCL1,ATP1A3,GPR146,CABP7,IGLON5,GAPVD1,FRMPD4,RASSF2,G3BP2,CDON,ELAVL3,RGS17,EMX2,COQ7,TMEM151A,DKK3,NCKAP1,WASF3,FAXC,GFRA1,PCDH17,GJB1,ZNF638,RAPGEF1,PTGDR2,IBA57,LSAMP,MDM4,CD200,PDE3A,GNG2,SNRK,TMLHE,CSRNP3,ATXN1,ANKRD28,EXOC7,MGRN1,ACSL6,TLR4,TNS1,DPF3" MicroRNA hsa-miR-93-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-19 7.90E-16 2.76E-19 2.54E-18 56 269 "ABR,ACLY,ACTN1,ALS2,ATP1A1,CANX,CBR1,LRBA,CDC42,KMT2C,KIAA1549L,PLXNA4,DCAF8,TOMM20,SV2B,HEYL,EEF1D,ELAVL3,ENO2,DMTN,MTSS1L,TESK2,FER,RGPD5,FYN,ZNF44,SRCAP,GPR162,CRCP,DIDO1,GRIK3,CIT,MYCN,NASP,NEUROD1,PDYN,SLC25A23,PSMD13,NCBP3,SCN7A,PEAR1,PUF60,DHX30,KANSL3,ARFGAP1,SPTAN1,GANAB,SUPT5H,TIAM1,PARD3,TPD52L2,TRIO,RUNDC3B,EIF4ENIF1,SLC35A4,WNK1" MicroRNA hsa-miR-328:PITA hsa-miR-328:PITA_TOP PITA 1.43E-19 8.01E-16 2.80E-19 2.58E-18 38 126 "ASIC1,USP37,HAP1,RUNX1T1,CABP1,SH2B1,FAM131B,DYNC1I1,EN2,TESK2,MEX3B,BRPF3,GPM6A,ATXN2L,LRRC75A,C5orf24,KIF2A,MN1,ZC3H12B,CLDN11,PDE4B,SDK2,MED1,SNRK,UHRF1BP1,GTDC1,LGR4,LRRTM4,SLITRK3,ST3GAL3,FAM214B,SLC8A1,WDTC1,SOX11,ZNF423,PLCB1,UNC5D,WIPF2" MicroRNA hsa-miR-661:PITA hsa-miR-661:PITA_TOP PITA 1.59E-19 8.94E-16 3.12E-19 2.87E-18 42 155 "SDE2,UNC5A,PITPNM2,APBA2,SEMA4G,MARK4,NCOA1,FMNL3,EVI5L,TAOK2,NRXN2,ZNF385A,RIMS4,ARHGEF4,DCAF8,RUSC2,DRP2,PHC2,EEF1A2,ELAVL3,USP21,TPPP3,PPARGC1A,TTBK1,RNF165,KLF12,BACH2,SYNPO,LRRC75A,MSI1,NEFH,NUMA1,ZNF827,DPF2,STX1B,FAM214B,RIMS1,LRRC4,CUX2,ZFP91,KLC2,SNX27" MicroRNA hsa-miR-662:mirSVR_highEffct hsa-miR-662:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-19 9.86E-16 3.44E-19 3.17E-18 41 148 "KCNH8,ADORA1,APP,CDK5R1,CLDN10,METTL6,SLITRK5,CYBB,HEPH,PARD6A,NYAP1,ZNF461,EFCAB2,ZNF605,KDM2B,LPAR4,GRIK4,NR3C1,LINC00839,MAEL,AGBL5,TLX1,LYRM9,PRIMPOL,NDUFS7,RDX,ZMAT4,ZNF532,ARMH4,SGK1,ITSN1,NTNG1,TEX2,BEX1,TMEM150C,TBX15,SIN3B,PRMT8,ANKRD20A2,RICTOR,DHX33" MicroRNA hsa-miR-6736-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-19 9.97E-16 3.48E-19 3.20E-18 53 244 "CLK4,PNMA8B,MTA3,STX16,MTMR3,CBS,NDST3,RTTN,TENM4,UBXN2A,ZBTB24,ELMO1,MRNIP,RGS17,IGSF6,RAPGEF6,MYOZ2,KDM2B,LILRA2,RAPGEF1,RFFL,PTPRT,KAT7,SCRG1,GPR155,MOG,SAMD5,JAKMIP3,CDK18,A2ML1,FITM2,ZNF793,PGBD4,SEMA6D,ATXN1,SLC1A7,PEX26,TRIM67,ATF7IP,LHFPL4,C11orf87,ZNF621,POGZ,SSTR2,ALG1,WWC1,AGTPBP1,SLC19A3,LEFTY2,CBX5,TMPRSS5,UPF3A,WIPF2" MicroRNA hsa-miR-718:mirSVR_lowEffct hsa-miR-718:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.84E-19 1.03E-15 3.59E-19 3.31E-18 61 316 "CC2D2A,FAM131A,PPFIA3,ARNTL,LINC00173,MARK4,CHID1,CDK5R2,USP6,CTH,DNM2,OPTN,EPB41L1,EFS,TBC1D16,GORAB,SLC9B2,NELFCD,TMEM107,APOPT1,TRAF3IP2,ZNF638,GPT2,STMN2,GRB10,LINC00839,AGBL5,LRRCC1,KIFC3,MEIS2,CDK18,TMIE,PLCB2,MAPKAP1,MED1,ZYG11B,RET,ATAT1,LRFN5,SCP2,SLC12A4,UNC80,LHFPL4,SS18,SYP,TBCEL,SMG6,TCF7,WDR7,USP32P1,FBXL16,KCTD2,TPM1,C9orf85,UBTF,VLDLR,SLC26A10,EML6,UPF3A,LRP8,MSRB3" MicroRNA hsa-miR-520a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-19 1.06E-15 3.68E-19 3.39E-18 40 141 "PCDH19,TAOK1,SEMA7A,APBB2,ZNF582,CDC25B,NRXN3,CLU,BTF3L4,C2CD2L,RASGRP1,REEP2,FOXO3,AFF2,CELF1,ZNF274,GPM6B,KCNH1,MPP2,ZNF827,ZNF426,PPP2R5E,PRKCB,MDGA2,SETD5,ELP2,RXRA,NCBP3,HES6,SGK1,PEX26,ATF7IP,SON,ARHGAP26,TACC1,AGMO,CSDE1,CIAPIN1,URM1,NELFE" MicroRNA hsa-miR-18a-5p:Functional MTI Functional MTI miRTarbase 1.97E-19 1.11E-15 3.86E-19 3.56E-18 55 262 "ABR,AS3MT,RNF157,PTCHD1,TAOK1,ATM,ATP1A1,ADAM15,CA12,CANX,LARGE1,TBPL1,DCAF4,DCAF8,LIN54,MATR3,TOMM20,KLHL3,F3,WAC,ZNF585B,RACK1,SEC24B,DCTN2,NBEA,MSL3,GNAS,NR3C1,BVES,AGFG1,HSF2,RBPJ,ZNF678,MBD1,MID1,PCDH9,PDE4D,PSAT1,FAM120C,CSRNP3,SON,CDK19,SYPL1,DICER1,CRB1,THRA,DAAM2,ZMYND8,UBC,RICTOR,ZNF711,ZNF708,ZFAND5,ITM2C,RNF146" MicroRNA hsa-miR-6721-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-19 1.12E-15 3.89E-19 3.58E-18 52 236 "PLEKHG5,ELFN2,CASKIN1,AMH,PHF12,KIAA1614,DPY19L3,HCN2,BSN,CAMK2A,BRSK2,NUMBL,CACNA2D2,MYADM,TM9SF4,IP6K1,DNAL1,DNAJC6,FAM13A,WAC,CELF1,CPLX1,AHDC1,GFER,GJB1,CRCP,B4GALNT4,MAP4,PPM1L,HS6ST3,FXYD6,ZC3H12B,NUMA1,PDE4A,PIK3R1,PKD1,PACSIN1,POLR2F,SARS,STUM,PEX26,TMCC1,SSTR1,PUM2,NACC2,CBX5,TPD52,RGMB,TMPRSS5,TMEM237,ITM2C,GAN" MicroRNA hsa-miR-384:PITA hsa-miR-384:PITA_TOP PITA 2.07E-19 1.16E-15 4.05E-19 3.73E-18 42 156 "PCDH19,TAOK1,PPP4R4,CAMK2G,FOXN3,KMT2C,SLC35F1,ABCG1,RIMS4,MFAP3L,POM121,SRGAP3,ST8SIA3,MBNL2,TENM1,RCAN2,UBE2E3,GFRA2,GGT7,CD200,MPP2,NCAM1,PDE4D,GPR85,CDK14,STRN3,PTN,ZNF532,CLIP1,FBXO11,SLC8A1,KBTBD4,RIMS1,NKAIN2,ERBIN,TCF4,R3HDM1,TSC1,CADM1,SLAIN1,ZNF189,SNX27" MicroRNA hsa-miR-4789-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-19 1.28E-15 4.46E-19 4.11E-18 54 254 "MTA3,ST3GAL5,C1orf52,CD81,TBRG4,COPB2,B4GALT6,KIAA1549L,SLC24A2,TBPL1,ANKRD44,MYADM,DGKG,DBT,PITPNC1,SV2B,CPEB2,CERCAM,ZBED3,MPP6,GABRG1,BRPF3,GCK,MMADHC,COPS8,SCIN,IL6ST,KCNA4,KLHL23,KCNK1,NCOA7,MYBPC1,NEXMIF,NDUFA5,OPHN1,PIK3R1,KANSL1,PKN2,SNRK,CSRNP3,SLC12A2,FAM126B,WDTC1,DIP2A,AJAP1,GPRIN3,SIK3,HHIP,BEX4,CSMD1,NR2C2,WNK1,LRP8,MVB12B" MicroRNA hsa-miR-181b-5p:Functional MTI Functional MTI miRTarbase 2.38E-19 1.34E-15 4.65E-19 4.28E-18 67 375 "SLC25A25,MTUS1,HECW2,OSBPL8,HFM1,ARRB2,CAPRIN2,BRINP2,ATM,ATP2B1,NMT2,PNKD,SEC24C,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,G3BP2,MTX3,FSD1L,FAM13A,ELN,EN2,STX2,EPS8,FGFR1,IQCG,GRIA2,DIDO1,HMGB1,ZDHHC15,IPO5,NCOA7,BLOC1S2,NFIA,NRDC,PPP2R5E,ZNF844,PBRM1,RPRD1A,MEG3,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,CPEB4,ZNF667,ZNF415,TMCC1,SPP1,UNC5B,RAP1GAP2,GANAB,KLHL7,PRRC2C,SLC35G2,SIRT1,DDHD1,TUBB2A,VSNL1,ZNF781,NSD2,ZNF23,SPIRE1,EMSY" MicroRNA "GGCACTT,MIR-519E:MSigDB" "GGCACTT,MIR-519E:MSigDB" MSigDB 2.53E-19 1.42E-15 4.94E-19 4.55E-18 37 121 "CDK10,SEMA4G,MARK4,DDX3Y,QKI,PCYT1B,ZNF385A,CLOCK,SPATA2,EFNB3,WAC,ZIC4,SCML2,NBEA,OGA,OPCML,XRN1,RETREG2,PTPRD,PTPRG,RAB5B,ARID4A,ZFHX4,FAM102A,YPEL4,BTBD7,SON,SOX11,ITPRID2,TBL1X,SYNE1,ARHGEF12,ZFP91,DPYSL5,KAT6A,ST8SIA2,GAN" MicroRNA hsa-miR-665:PITA hsa-miR-665:PITA_TOP PITA 2.55E-19 1.43E-15 4.98E-19 4.59E-18 49 212 "SDE2,AMPH,OGT,CCAR2,SYNJ1,CACNA1G,NIPBL,RIMS4,CTNND1,TM9SF4,HP1BP3,WDR20,DYNC1I1,EFNA3,RCAN2,ANKRD13B,EXTL2,CORO2B,TOMM40L,FCGRT,AGAP3,EVL,GABRB3,BRPF3,PCDH17,TTBK1,GNAO1,IBA57,KCNB1,KCNN3,LMO1,NCAM1,NNAT,NRGN,PALM,GNG2,RASGEF1B,KIRREL1,FAM19A1,KIF21B,AJAP1,SYN1,SMG6,DOK6,FNDC5,AMOT,SF1,POLR3H,KAT6A" MicroRNA hsa-miR-491-5p:Functional MTI Functional MTI miRTarbase 2.55E-19 1.44E-15 4.99E-19 4.59E-18 44 172 "CPNE2,AP1B1,CASKIN1,TRMT9B,AMPD3,ARRB1,ARRB2,DIRAS1,PYGO1,PHYHIP,PLEKHM1,ABCC5,APH1A,EGFR,MRO,ING4,ELN,SEPT9,SESN1,MIER3,SHISA6,SOWAHA,MAP4,GIT1,GPR173,PFKFB2,PKM,PLEC,SLC25A23,SDK2,KIAA0895L,SBF1,ATXN2,BTBD3,SMTN,KDM4B,PEG10,CAMTA2,SLC19A3,NACC2,KCTD2,UBTF,ZNF708,ZNF138" MicroRNA hsa-miR-597:PITA hsa-miR-597:PITA_TOP PITA 2.60E-19 1.46E-15 5.07E-19 4.67E-18 39 135 "ASIC2,GPR158,ARHGAP20,CACNB2,NRXN3,QKI,RCHY1,PLCXD3,G3BP2,FOXO3,B4GALNT1,GPM6A,GRIK1,NEGR1,KCND2,LIFR,PTOV1,NCAM1,ZC3H12B,CNOT4,MED1,USP47,SEMA6D,SCN2A,SGK1,CPEB3,FHOD3,SLITRK3,FAM126B,MYT1L,SOX11,SP4,GANAB,WDR7,PUM2,KAT6B,RPRM,SLAIN1,TMEM237" MicroRNA hsa-miR-6826-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.69E-19 1.51E-15 5.25E-19 4.83E-18 42 157 "ACTN2,ASGR1,ASPA,ATP1A2,DCAF5,NIPA1,NUMBL,PNKD,TENM4,CYBB,KLHL5,ABI2,STARD3NL,WAC,CELF1,SEPT9,GBX2,KCNMB4,GPR26,GRID1,FAM107A,PADI2,SHISA6,HSP90AA1,KCNJ10,MDFI,CTNNA3,DDR2,RDX,GTDC1,SETD5,ZFP1,ZHX3,NSFL1C,TMEM151B,THRA,C5orf64,ZNF24,URM1,PPP1R3F,ITM2C,NETO1" MicroRNA hsa-miR-4319:mirSVR_highEffct hsa-miR-4319:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.75E-19 1.54E-15 5.36E-19 4.94E-18 73 436 "KCNH8,ASPHD1,ABHD6,NCKAP5,ADD2,CNIH2,SHTN1,ARNTL,CDK13,ASPH,ATM,USP2,P2RX6,AIFM1,SULT4A1,LY86,SLC4A8,HINFP,MICAL2,IST1,ZEB2,RABGAP1L,SPEG,SEMA4D,CGREF1,KIAA1841,LOXL3,RABL2A,AGBL5,MSL1,ZNF546,KCNMA1,KCNN2,KLRC2,LIG4,MBD1,MEIS2,MYT1,CHAMP1,PAK3,EXOSC10,DRAM2,MASP1,TMEM260,RASGRF1,RASGRF2,SLC6A15,SEC61A2,TMLHE,COPZ1,BCAN,ABLIM3,PPP4R3A,CDK5RAP2,ZSCAN29,DIP2A,VWA3A,C18orf54,MTMR14,NPL,RGMB,TRIO,SLC35A4,KLC2,TRIM9,ZNF177,EMSY,STMN4,SEMA3B,EPM2A,TIGD6,IFT88,SLC4A10" MicroRNA hsa-miR-342-5p:mirSVR_highEffct hsa-miR-342-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.79E-19 1.57E-15 5.44E-19 5.01E-18 64 347 "ACLY,PDZD4,SPTBN4,CCAR2,KSR1,CASTOR3,MTMR2,DDR1,PLEKHB1,DGCR9,DNAJB5,CNTFR,WHRN,SEC24C,KLHL3,SNAP91,DPH1,DTNA,PHF20L1,HSPA12B,ACSL4,ZIC4,GTF2IRD2,FGF11,SUCO,GABRB1,SIGLEC8,PPARGC1A,GNG3,GPD2,FAM222A,SLC35G1,KCNK2,MMP16,MN1,OCRL,PBX1,PRKCG,PTPRH,PTPRN2,TMEM255A,OXR1,RDX,SEC61A2,MEG3,ATAT1,KCNIP2,CPEB3,PAAF1,KBTBD4,SLC12A4,ATF7IP,KIF13A,NFASC,STXBP1,AJAP1,FGD4,MLST8,WDR7,OBSL1,TNS2,GAL3ST3,FAM47E,UBE3B" MicroRNA hsa-miR-378a-5p:Functional MTI Functional MTI miRTarbase 2.82E-19 1.58E-15 5.50E-19 5.06E-18 68 386 "SLC25A25,TMEM132B,TAOK1,TNRC6C,ASTN1,ATM,CACNB2,STOML1,DNAJB5,ENTPD4,MYADM,FGFR1OP2,TCAF1,DBT,RABGAP1L,AP4B1,SIGLEC8,SRCAP,PPARGC1A,HAS2,DDX19B,ATCAY,C2orf72,PLD5,KCNN1,KCNN3,MAN2A2,CHST6,PTOV1,C10orf105,NODAL,P2RX7,TMOD2,PIK3C2A,GPSM2,ING3,POLR2F,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,UEVLD,HSPA4L,NUBPL,ZNF430,SLC15A2,ANKRD36,CMTR2,FAM126B,CLUAP1,ZBTB43,SSTR2,MAPK8IP3,STAC2,KLHL7,ARC,CYB561A3,ZMAT3,ZNF34,SGK3,UGT8,USP1,MEAF6,ZNF708,SSPN,GAN" MicroRNA hsa-miR-339-5p:TargetScan hsa-miR-339-5p TargetScan 3.28E-19 1.85E-15 6.40E-19 5.89E-18 40 143 "PLEKHH1,PDZD4,CDK13,NRP2,MTMR3,HAP1,RUNX1T1,NRXN1,PPP6R2,CTIF,JAKMIP2,DLG3,ERBB4,FHL1,FLT1,BRSK1,PCDH17,LYVE1,PRUNE2,ARHGAP36,HNRNPK,KCND3,GPR62,LDLRAD3,SCAMP5,MDGA1,NNAT,NOVA1,PDE4D,PFKFB3,CDK14,PURG,MED1,CNNM2,ELOVL2,RORB,COPZ1,KIF1B,NFASC,DAAM2" MicroRNA hsa-miR-6124:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-19 1.91E-15 6.64E-19 6.11E-18 45 181 "MTA3,CASKIN1,PDXK,USP2,HAPLN1,CRY2,CTNND1,PYGO1,KIAA0513,RAB39B,ABCC9,TUBA1B,AMOTL2,CELF1,GABRB1,MALT1,CRCP,TNRC6A,GNG3,PRUNE2,DIPK1C,GRIN2D,PACSIN2,KCND3,MAOB,CCDC80,ADAM22,NASP,SH3TC2,PRRT2,CPEB3,BCAN,SLC6A8,SLC8A1,DIP2A,ZMAT3,TPM3,ZKSCAN5,UBTF,VAV2,SF1,LYPD6,SLC38A1,CSDE1,XKR7" MicroRNA hsa-miR-5693:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-19 1.93E-15 6.68E-19 6.15E-18 65 358 "ABCF1,CLK4,AS3MT,XKR4,TXNDC16,SLC7A14,DOCK11,FOXK1,BTF3L4,GREB1,IP6K1,YTHDC1,GNE,KRBA2,TUBD1,POLR1B,SEC23B,MSANTD4,CNDP1,GRK4,KAT7,SHISA6,IBA57,LIMS1,GPR155,MAP4,LYPLAL1,NEUROD2,ZNF713,OLA1,A2ML1,GPSM2,APTX,PEX2,PLEKHB2,SH3TC2,RAP1GDS1,ZYG11B,ERI2,C12orf49,ELP2,SNX22,UEVLD,NCBP3,HSPA4L,SH3BP2,R3HDM2,PEX26,SLC8A1,ANKRD36,BDP1,ZNF621,ZSCAN29,KLHL7,ALG1,WWC1,ZNF34,ZNF106,MEAF6,LAT2,ZNF708,EVI5,WIPF2,RNF170,AP3B2" MicroRNA hsa-miR-1298-5p:TargetScan hsa-miR-1298-5p TargetScan 3.45E-19 1.94E-15 6.71E-19 6.18E-18 37 122 "C3orf14,BEND6,OSBPL6,APC,ATP2B2,BMP7,CACNA1I,BTRC,CFL2,KIAA1549L,BTF3L4,IGDCC3,CNTNAP2,FAM131B,CYBB,RAB39B,ABI2,GABRB3,FAM184B,B4GALNT4,KLF12,AGFG1,LRRTM3,CHIC1,MITF,NCAM1,PDE4D,GNG2,PPP2R2C,CNNM2,RXRA,ANKRD12,KAZN,NR2C2,RGS7BP,CERS6,FXR1" MicroRNA hsa-miR-362-5p:PITA hsa-miR-362-5p:PITA_TOP PITA 3.47E-19 1.95E-15 6.75E-19 6.21E-18 39 136 "SYS1,ZBTB10,NOL4,NIPA1,NRXN3,RBM39,CREB5,RIMS4,CASP8AP2,APH1A,TMEM132E,ERBB4,MRVI1,CORO2B,RAPGEF6,C15orf41,MIER3,HSP90AA1,GPR88,PLP1,STRN3,PRKACB,PTPRD,PTPRE,CEP97,REV3L,SLC25A36,RMI1,SATB1,LRRTM4,CASC3,ST6GAL1,CPEB4,NUDT10,SYN1,SATB2,ARHGEF12,TRPS1,SYNC" MicroRNA "AGCATTA,MIR-155:MSigDB" "AGCATTA,MIR-155:MSigDB" MSigDB 3.53E-19 1.98E-15 6.87E-19 6.33E-18 38 129 "FAM135A,ATP2B1,BACH1,QKI,CSF1R,BOC,HDAC4,TOMM20,G3BP2,DYNC1I1,C3orf18,CAB39,GPM6B,PSIP1,KCNN3,LRP1B,MEIS1,NFIX,NOVA1,PCDH9,GPR85,STRN3,PKIA,WBP1L,SATB1,FBXO11,SLA,SMARCA4,SOX1,SOX11,TAB2,SYPL1,CAMTA1,TRIM2,C5orf64,SGK3,ZIC3,SCG2" MicroRNA "ATGTCAC,MIR-489:MSigDB" "ATGTCAC,MIR-489:MSigDB" MSigDB 4.01E-19 2.25E-15 7.79E-19 7.18E-18 31 84 "PCDH10,NCOA1,DDX3Y,ATP2B3,BMP7,BRSK2,CLOCK,RBM12,CELF1,GPD1,ADAMTS13,BACH2,LRRC75A,IPO5,NOVA1,NTRK3,PDE4D,PURG,POU3F2,OXR1,RBBP6,BAALC,HUNK,SCN3A,SGK1,SP4,UNC5D,WASHC4,NSD1,XPO1,ST8SIA2" MicroRNA hsa-miR-6134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-19 2.60E-15 8.99E-19 8.28E-18 65 360 "ABCF1,ARID1A,HACE1,FOXK1,PTBP2,CBS,CFL2,SUMF2,ACBD5,CRY2,PITPNM3,RUBCN,GAPVD1,KIAA0513,DNAL1,PLEKHM1,HP1BP3,TMTC1,MRO,ABI2,FGFR1,NEURL4,MTHFD2,CSDC2,CRCP,SHISA6,IGF1,MAOB,PABPC1L2A,FXYD6,TBC1D25,NLE1,FTO,EPN1,RETREG2,FAT3,DIRAS2,NCR3LG1,MTMR10,RAB5B,CEP97,PLEKHB2,RAP1GDS1,C12orf49,PGBD4,FAM161B,NCBP3,AMBRA1,EPN2,SP2,AGTPBP1,CRTC1,WBP2,TUBB2A,BCL2L13,LAT2,PORCN,ZNF17,ZNF28,EVI5,CIAPIN1,WIPF2,PARP11,ZDHHC20,SSPN" MicroRNA hsa-miR-1286:PITA hsa-miR-1286:PITA_TOP PITA 4.70E-19 2.64E-15 9.12E-19 8.40E-18 37 123 "CSMD2,GAS7,FAM131A,MARCH3,CFL2,QKI,SEC24C,DOCK4,DLG2,RBM12,TMEM132E,ELAVL2,GAP43,PCDH17,GNG3,GRIN1,KLF12,BACH2,HNRNPK,KCNMA1,CHIC1,MEF2C,NFIX,TRHDE,PRRT2,RORB,SCP2,CPEB3,FBXO11,WDR37,ZNF423,NFASC,ST5,VAMP1,CNTN2,EHBP1,WNK3" MicroRNA hsa-miR-1258:PITA hsa-miR-1258:PITA_TOP PITA 4.75E-19 2.67E-15 9.22E-19 8.49E-18 38 130 "SLC25A25,OSBPL8,ASCL1,ATP2B3,ARMC8,RIMS3,KCTD8,ELMSAN1,DYRK1A,EMX2,ZIC4,FGF12,FOXO3,DNER,PPARGC1A,GPT2,ADAMTS6,ZIC5,LAMP2,MBP,NEXMIF,PCSK2,GNG2,PMP22,PPP2R5E,GTDC1,ZFHX4,KIF21A,ABLIM3,SP4,SYT1,TCF12,R3HDM1,UBE2H,WIPF2,MVB12B,PAK5,SLC4A10" MicroRNA hsa-miR-1267:PITA hsa-miR-1267:PITA_TOP PITA 5.13E-19 2.88E-15 9.95E-19 9.17E-18 41 152 "HECW2,PCDH19,APC,SHROOM2,PPP4R4,ATP1B3,ATP2B1,JAZF1,CAMK2D,RUNX1T1,C1orf52,CSNK1G3,SOCS5,USP6NL,PLEKHM1,CHRDL1,EFNB3,ATP8A1,AGAP2,AFF2,PPARGC1A,GRIA1,SOX21,KCNA1,PABPC1L2A,PTPRD,SLC25A36,SCN2A,PPP4R3A,SP4,NKAIN2,SYN2,TBL1X,TCF7L2,DICER1,FLRT2,MKRN3,LYPD6,MAP3K12,MFF,PRDM10" MicroRNA hsa-miR-642a-5p:Functional MTI Functional MTI miRTarbase 5.41E-19 3.04E-15 1.05E-18 9.66E-18 50 224 "MTA3,ARRB1,ATP2B1,CDH8,GPR37L1,SLC22A6,STOML1,CRY2,TENM4,RGS6,PITPNM3,UBXN2A,PLCXD3,MYADM,FRMPD4,PHF19,TMEM170A,RUSC2,ST8SIA3,HEYL,EMX2,ZNF391,FER,DKK3,GPR75,GLUL,ZNF638,GRID1,XRRA1,MYO5A,NEXMIF,NODAL,KSR2,OLR1,ZDHHC22,GLIPR1L2,PTPRG,GTDC1,ASIC4,GALNT10,WDR37,CLUAP1,ZSCAN29,TMEM151B,DOK6,KCNK12,SLC30A3,VANGL2,FRMD6,JPH3" MicroRNA hsa-miR-140-3p:Functional MTI Functional MTI miRTarbase 5.41E-19 3.04E-15 1.05E-18 9.66E-18 50 224 "SLC24A4,KSR1,FOXK1,CD38,CRY2,KIAA0040,GAPVD1,PITPNC1,POM121,CHRDL1,MAMLD1,EPB41,TUBA1B,ATP8A1,FDFT1,PCYOX1,GGT7,NUDT21,NCKAP1L,KIF5A,LAMP2,MOBP,MYO6,NFYA,PLCL1,PSAT1,TNPO2,MAPK8,NWD1,RPRD1A,SETD5,CLIP1,ATXN1,DRAXIN,STUM,KIF21A,SLC2A5,ZNF423,NFASC,SS18,DNAJC9,ANKRD12,THRA,CADM1,UBTF,PITPNB,TBC1D15,CLDND1,SLC30A3,SPATA13" MicroRNA hsa-miR-585:mirSVR_lowEffct hsa-miR-585:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.43E-19 3.05E-15 1.05E-18 9.70E-18 45 183 "FAM43B,GPRIN1,SORCS1,HACE1,CC2D2A,PITPNM2,UPRT,KALRN,ANKRD44,CSF1R,LYPD1,PHC2,CELSR3,EMX2,CEND1,ZNF589,FGF11,FLYWCH1,NSG2,GPR12,GRM7,VSIG4,SYNPO,KCNJ9,KCNJ10,OPRL1,MTRF1L,PPP2R5C,SLC25A36,STK32B,ATXN2,HOGA1,FAM214B,CDK5RAP2,DBNDD2,SLC37A2,KLHL4,TRIO,LINC00689,GUSBP1,LYPD6,EML6,ZFAND5,RTN4,UBE3B" MicroRNA hsa-miR-574-3p:mirSVR_highEffct hsa-miR-574-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.68E-19 3.19E-15 1.10E-18 1.02E-17 40 145 "ATP2A2,MYOM1,CBR1,CLTC,FAM19A5,SLC4A8,HINFP,USP6NL,FBXL5,GORAB,DKK3,GALC,GRIA4,INSM1,KCNK1,KLC1,MN1,GIT1,COL28A1,NODAL,STRN3,SNRK,USP47,FAM66C,RFX3,RGS3,RPRD1A,CCDC82,RXRA,MIR124-2HG,NTNG1,HKDC1,TMCC1,FAM219A,SP2,TAB2,SYNE2,ATMIN,WASHC4,FIP1L1" MicroRNA hsa-miR-377-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-19 3.20E-15 1.10E-18 1.02E-17 85 569 "ABCF1,NDRG3,PLEKHG5,SLC24A4,HECW2,HACE1,ZNF578,TRMT9B,AQP6,CDC14B,EIF4G3,DOCK11,PTBP2,CBS,CBFA2T2,MYOM2,ARHGEF2,CDR1,CCPG1,JAM2,NRXN3,ZNF385A,USP6NL,GAPVD1,KIAA0513,TBC1D5,DNAL1,DBT,HP1BP3,MTX3,DNAH9,MRO,RASA4,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,FAM198B,ZNF585B,SCML2,FECH,KBTBD12,DISC1,CRCP,GNAS,GNG4,LILRA2,KIF3A,KAT7,SCRG1,IGF1,TJAP1,IBA57,CCDC80,MXI1,NUCB1,PPP3CC,NCR3LG1,CEP97,RBBP8,ALG9,GSTCD,PTGR2,NCBP3,FNIP1,MAGI3,ATF7IP,CPEB4,SCN3B,FNBP1,CDK19,TAB2,ACSBG1,FAM208A,TPCN2,DICER1,BHLHB9,TPM3,RFTN2,LAT2,CLDND1,ZNF17,ZNF70,EVI5" MicroRNA hsa-miR-619:PITA hsa-miR-619:PITA_TOP PITA 6.34E-19 3.56E-15 1.23E-18 1.13E-17 43 168 "RALGAPA1,ADCY6,OGT,TMEM263,RUNX1T1,CERS5,FOXN3,TMEM184B,CNR1,AHCTF1,FAM131B,FRMPD4,CPEB2,PHC2,RBM12,EGR3,EPB41,FGF13,FOXG1,EVL,CAB39,SMAP1,RBPJ,SYT9,MID1,SAMD5,MSI1,PCDH9,PDE3B,PDE1B,MAPK9,PTPRD,AMBRA1,CHD9,SOX11,TAL1,ARHGEF12,TGFBR3,TMEM237,CA10,STMN4,GAL3ST3,WIPF2" MicroRNA hsa-miR-625:PITA hsa-miR-625:PITA_TOP PITA 6.36E-19 3.57E-15 1.23E-18 1.14E-17 38 131 "CSMD2,ARID1A,HECW2,PCDH19,FUBP1,JAZF1,CACNA2D2,CLTC,ZNF385A,CLIP3,PHYHIP,SLC12A6,DUSP9,KMT5B,ATXN2L,HNRNPK,IGF1,SCAMP5,NEUROD2,NFIX,POU3F2,PPP2R2C,TMEM260,UBR7,SETD5,FBXW7,ATXN1,CPEB4,SMARCC2,ANKFN1,SOX2,MTCL1,TRIM2,TRPS1,AMOT,CELF4,CA10,CSDE1" MicroRNA "ATGCAGT,MIR-217:MSigDB" "ATGCAGT,MIR-217:MSigDB" MSigDB 6.66E-19 3.74E-15 1.29E-18 1.19E-17 34 104 "OGT,VAT1L,ADGRB3,CAPN3,DLGAP2,CHN2,NIPBL,ST18,MYEF2,DYRK1A,YAF2,TACC2,STAG2,LRRC37A6P,PCDH17,GPM6A,KLF12,NEUROD1,NFIA,NOVA1,SEPT4,POLG,ARMH4,FBXO11,SLITRK3,SOX11,ELOVL4,STX1A,TACC1,FBXW11,SIRT1,TBC1D15,RICTOR,SENP7" MicroRNA hsa-miR-548n:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-19 3.90E-15 1.34E-18 1.24E-17 54 260 "SLC12A5,PTCHD1,MTUS1,MARCH4,FAM135A,PTBP2,TOGARAM2,NECTIN3,PYGO1,YTHDC1,RAB39B,DPYSL2,EFNA2,KATNAL1,SUCO,ZMAT1,SALL3,MTHFD2,CRCP,TNRC6A,PRRC2B,GPR26,GRM5,MAP4K5,SOWAHA,ZNF678,TTYH2,TM6SF1,PFKFB2,ZFYVE21,PSAT1,SLC25A36,C12orf49,MCMBP,CLIP1,SOX6,TRA2B,LRRC55,SON,PEG10,KIF1B,SMOC1,CAMSAP2,RBFOX2,TRPS1,RPL7L1,MTCH1,VSNL1,ZNF154,DHX33,PPP1R3F,WNK3,PAK5,JMJD1C" MicroRNA hsa-miR-5589-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.19E-19 4.04E-15 1.39E-18 1.28E-17 62 334 "ZNF578,TAOK1,CEP126,KIF6,PPFIA4,ARHGDIA,ATP1B3,MTMR9,BCL2L2,LDHD,FOXK1,DIS3L,PLAA,BTF3L4,IGDCC3,SOCS5,UBXN2A,DNAL1,RABGAP1L,SLC12A6,ABI2,IRAK4,MRPL37,TLR7,GTF2IRD2,ZBED3,TRAF3IP2,KIAA1841,CRCP,RNPS1,GRIK3,MFSD2A,HAS2,HMGB1,ZNF491,KCND3,CYP27C1,GPR155,MBD1,CHST6,CCDC80,SPATA6,OCIAD1,PEX2,RAB5B,C12orf49,FOXRED2,SBF1,DRAXIN,GALNT10,HSPA4L,SP2,EMC1,WWC1,GPRIN3,ZMAT3,CBX5,PARD3,NSD2,ZNF708,TRIM16L,MPPE1" MicroRNA hsa-miR-1234:mirSVR_lowEffct hsa-miR-1234:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.33E-19 4.12E-15 1.42E-18 1.31E-17 71 423 "ASPHD1,PPFIA1,PPFIA3,CDK10,ATP6V0A1,CCKBR,SRSF11,CHGA,SRP14-AS1,SIRPA,RHOBTB1,EDN3,OPTN,CELSR3,APH1A,EIF1,ATP8A1,OLFM1,SLC37A3,ERGIC3,BRSK1,BRPF3,USP19,PPARGC1A,TNRC6A,LOXL3,GPD1,TDRKH,GPR17,ADAMTS13,ATE1,MAEL,PTGDR2,AGBL5,LRRC75A,KCNK1,LIMS1,MTR,OGG1,PKD1,NLE1,PLXNB3,NKAIN4,MAPK4,CCDC82,CCDC102B,TCP11L1,LRRK2,PAQR6,MEG3,TRAPPC13,SH3GL2,FRMPD1,CHD9,SEPHS1,SCMH1,INAVA,TNIK,CAND2,SEPT8,GSE1,SEMA4A,TMPO,KCNE5,TSN,ZKSCAN5,SGK3,OSBP2,SLC30A3,SEMA3B,CASC15" MicroRNA hsa-miR-1293:PITA hsa-miR-1293:PITA_TOP PITA 7.89E-19 4.43E-15 1.52E-18 1.40E-17 29 74 "ELFN2,RTL9,SEMA6A,SEMA4G,VSTM2A,NOG,CNR1,SRGAP3,EIF4G1,PPARGC1A,KCNMA1,MEIS1,MEIS2,NEXMIF,CNOT4,SH3KBP1,PSD,GTDC1,ZFHX4,ROBO2,NCBP3,SLITRK3,PALLD,TAB2,CLASP2,GANAB,VAMP1,POLR3H,PARP6" MicroRNA hsa-miR-1273g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-19 4.43E-15 1.52E-18 1.40E-17 79 507 "XKR4,PNMA8B,GRAMD1B,SLC24A4,HACE1,TXNDC16,PHF12,AMER3,AQP6,CDC14B,PRX,ZNF555,CAMK2G,SLC16A4,CBFA2T2,NRXN3,COL9A2,HINFP,SUSD5,UBXN2A,NOS1AP,MYADM,TMEM170A,DNAL1,HP1BP3,MTX3,MRNIP,EPB41,KATNAL1,ATP13A4,FUT9,ZNF234,FAXC,GPR75,KIAA1958,RFFL,KIF3A,MFSD2A,DDX19B,MIER3,DOCK7,KCNN3,CHST6,CCDC80,ZC3H12B,SLC11A2,MINDY2,PPP3CB,UHRF1BP1,STK32A,OCIAD1,TMEM145,ZNF844,TRIM68,KLHL11,KLHDC8A,ALG9,ATAT1,ATXN2,MAGI3,KANSL3,SEPHS1,EMC1,MCF2L2,LHPP,SSTR2,TMEM151B,ARL10,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,PLPP4,ZNF138,WNK1,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-6787-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.10E-19 4.55E-15 1.56E-18 1.44E-17 53 252 "CLK4,AS3MT,MTA3,TAOK1,STX16,DOCK11,RTTN,ENTPD4,PLXNA4,UBXN2A,FBXL5,HEYL,GPR61,MRO,MRNIP,COQ7,IGSF6,TMEM151A,DOT1L,MYOZ2,GPR75,KDM2B,LILRA2,RAPGEF1,RFFL,KAT7,ZNF546,GPR155,MOG,SAMD5,A2ML1,FITM2,CEP97,ZNF793,PGBD4,PTGR2,PEX26,SLC15A2,ATF7IP,ERC1,ZNF621,SSTR2,TMEM178B,ALG1,WWC1,AGTPBP1,SLC19A3,SMUG1,MGAT5B,MEAF6,DPYSL5,URM1,MPPE1" MicroRNA hsa-miR-589:PITA hsa-miR-589:PITA_TOP PITA 8.34E-19 4.68E-15 1.61E-18 1.48E-17 36 118 "GPR158,PCDH19,SEMA6A,SPOP,GPRASP2,SYNJ1,CAMK2A,ZMYM4,MAGI1,AKAP6,RGS6,PLCXD3,GAPVD1,DSCAM,ELAVL3,MED12L,NBEA,NPTN,TNRC6A,KAT7,MAP2,MAT2A,MYO6,MYT1,NEFM,PURG,PRKAB2,PKN2,SOX11,PEG10,SSTR1,SYN1,UNC5D,SZT2,TMEM237,WNK3" MicroRNA hsa-miR-3612:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.38E-19 4.71E-15 1.62E-18 1.49E-17 71 424 "ABCF1,PLEKHG5,ADD2,PNMA8B,TRMT9B,KIF6,CPNE5,ARHGDIA,ATM,DDR1,CANX,CLU,LETMD1,CRY2,NCOR2,IPCEF1,RASSF2,LIN54,TMEM170A,DNAL1,SGSM2,SEC16A,RASA4,MRNIP,ANKMY1,KATNAL1,MRVI1,TRMO,HHIPL1,NEURL4,B4GALNT1,MTHFD2,SESN1,AHDC1,CSDC2,CRCP,GLUL,KIAA1958,GNG4,KIF3A,DDX19B,SCRG1,IBA57,KLHL23,SAMD5,CCDC80,NBL1,NUCB1,PDGFRA,TMOD2,PLEC,PLXNB1,RETREG2,ZNF793,SETD5,NCBP3,SLC30A10,FAM102A,MAGI3,TRIM67,ATF7IP,ERC1,PEG10,IQSEC2,ZSCAN29,ACSBG1,USP22,PPIL6,SSBP2,ZNF70,INTS3" MicroRNA hsa-miR-125a-5p:Functional MTI Functional MTI miRTarbase 8.40E-19 4.72E-15 1.62E-18 1.49E-17 55 270 "PLEKHG5,MTUS1,KIF6,OGT,ZBTB10,PRC1,LONRF2,ZNF385A,PREPL,CREB5,HDAC4,IP6K1,ZEB2,GUCD1,NR1D2,EDN1,EGFR,ERBB2,TACC2,SMC2,MUM1,NEGR1,JAK2,SLC35G1,LIFR,ARHGAP12,MAT2A,NTRK3,OPRL1,PC,PDPK1,HMGCLL1,TNPO2,PPP2R5E,MAPK8,MASP1,UBR7,EMID1,MEG3,ATXN1,COPZ1,FERMT1,PEG10,DIP2A,TMEM136,PCDHGB2,PUM2,TPM4,TRPS1,XPO1,ZNF177,DHX33,STOX2,WNK3,TMEM63C" MicroRNA hsa-miR-3184-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.60E-19 4.83E-15 1.66E-18 1.53E-17 45 185 "GPRIN1,PNMA8B,AK2,ARRB2,ASPH,FOXK1,TRIM41,ARHGEF2,EVI5L,TMEM184B,SLITRK5,NOS1AP,SPATA2,RPS6KL1,ABCC5,EIF1,ANKRD13B,BRSK1,NKX6-2,SEPT9,AHDC1,GJB1,POLL,PRRC2B,B4GALNT4,GRID1,RNF165,KCNK3,MDM4,MMP17,NFIX,OLR1,PFKFB3,MTRF1L,SLC2A5,LIMS2,NFASC,TAB2,MAPK8IP3,SEPT8,AJAP1,NSD1,RPL7L1,URM1,WIPF2" MicroRNA hsa-miR-668:PITA hsa-miR-668:PITA_TOP PITA 8.93E-19 5.02E-15 1.72E-18 1.59E-17 31 86 "USP37,CACNA1A,CAMK2G,DNAJB5,ARMC8,GOLGA7,EML1,EMX2,EPB41,BRPF3,TOX3,GNAO1,PRRC2B,ATXN2L,NEGR1,IGF1,MAPT,KITLG,CNOT4,PCDH9,PDE3B,POU3F2,MED1,SP4,CDK19,CLASP2,NCDN,TPD52,POLR3H,SMARCAD1,NAV3" MicroRNA "GGCCAGT,MIR-193A:MSigDB" "GGCCAGT,MIR-193A:MSigDB" MSigDB 8.93E-19 5.02E-15 1.72E-18 1.59E-17 31 86 "KCNH8,CDK10,STX16,CALB1,CAPN3,RUNX1T1,TAOK2,ZC3H11A,DYRK1A,E2F6,EN2,ERBB4,ETV1,ANKFY1,KIT,LAMP2,CAMK2N2,STMN1,MKLN1,MMP16,MYCN,NOVA1,PPP2R5C,SON,SPATA7,ZHX3,CAMTA1,ARHGEF12,LRRC8A,ZIC3,NAV3" MicroRNA "GGCCAGT,MIR-193B:MSigDB" "GGCCAGT,MIR-193B:MSigDB" MSigDB 8.93E-19 5.02E-15 1.72E-18 1.59E-17 31 86 "KCNH8,CDK10,STX16,CALB1,CAPN3,RUNX1T1,TAOK2,ZC3H11A,DYRK1A,E2F6,EN2,ERBB4,ETV1,ANKFY1,KIT,LAMP2,CAMK2N2,STMN1,MKLN1,MMP16,MYCN,NOVA1,PPP2R5C,SON,SPATA7,ZHX3,CAMTA1,ARHGEF12,LRRC8A,ZIC3,NAV3" MicroRNA hsa-miR-591:PITA hsa-miR-591:PITA_TOP PITA 9.38E-19 5.27E-15 1.81E-18 1.66E-17 34 105 "CASK,ATP2B1,ATP2B2,SYNPR,MAP4K4,ZNF385A,DTNB,EGR3,ETV1,CACNG3,TESK2,MEX3B,MEGF11,GRM3,MIER3,NEGR1,INSM1,KCNK2,ARHGAP12,HCN1,GPR85,EPB41L4B,PPP3CB,MAPK10,SNRK,PEX5,ITSN1,PPM1E,ERC1,GANAB,TCF4,NSD1,TJP1,TUBB2A" MicroRNA hsa-miR-6818-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.61E-19 5.40E-15 1.85E-18 1.70E-17 42 162 "SORCS2,SEMA6A,RUNX1T1,CCNT1,SLC22A6,NRXN1,CLOCK,NCAN,PPP1R16B,ST18,JAKMIP2,BLOC1S6,DMD,EN2,EPHA5,KATNAL1,FGF14,TRMO,CAMKK2,GFRA1,GLYR1,CBX1,SYNPO,KCNB1,CLVS2,IPO5,MITF,HS6ST3,OXTR,KCNK10,ZNF655,PLP1,PPP3CB,SH3TC2,TTLL7,SATB1,MGRN1,ZEB1,TNR,DOK6,VSNL1,PORCN" MicroRNA hsa-miR-2681-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.73E-19 5.47E-15 1.87E-18 1.73E-17 40 147 "ARID1A,ADARB2,HFM1,IGDCC3,GPRASP1,DCAF8,YTHDC1,G3BP2,EBF1,ABI2,ASB3,ELAVL3,RAB9B,FDFT1,JKAMP,HHIPL1,PRRC2B,NUDT21,ZHX1,RBPJ,IBA57,KCNN3,NEUROD1,SNTG1,PROX1,ENOX1,ACER3,RXRA,CNKSR2,NPAS3,MPRIP,ARHGAP9,SLC44A1,SGK3,VLDLR,CELF4,DHX33,KAT6A,JMJD1C,FXR1" MicroRNA hsa-miR-508-5p:Functional MTI Functional MTI miRTarbase 9.78E-19 5.49E-15 1.88E-18 1.73E-17 76 477 "XKR4,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,ARSE,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,C2CD2L,KLHL3,MTX3,FSD1L,EBI3,EPB41,ANKFY1,TRMO,ZNF234,CRCP,GPR75,RAPGEF1,KIF3A,MFSD2A,FICD,DDX19B,AGBL5,DOCK7,KCNH1,KCNN3,CHST6,CCDC80,ZC3H12B,SLC11A2,PAX6,ABCB1,CCSER2,MTRF1L,PSAT1,TNPO2,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ALG9,ATAT1,ZNF331,HES6,IL17RB,MAGI3,SEPHS1,FNBP1,EMC1,MCF2L2,C3orf70,TMEM178B,ARL10,TNR,PPIL6,SSBP2,ZNF610,UBC,USP1,TBC1D15,PLPP4,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-1251:mirSVR_highEffct hsa-miR-1251:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.95E-19 5.59E-15 1.91E-18 1.76E-17 69 405 "KCNH8,GRAMD1B,KIDINS220,MTUS1,GPR158,UPRT,PPP4R4,SYNJ2,NAE1,VXN,TMEM257,CASC2,CNOT8,LHX2,SLC35F1,KATNAL2,ARHGAP24,KIAA0586,MFAP3L,HS3ST4,LRRC17,DUSP27,TUBB3,KAT8,ZNF589,UBE2E3,POMT1,SPECC1,ERGIC3,DOT1L,GHDC,MTHFD2,LRRC37A6P,SULT1C4,PPARGC1A,BRD8,PCDH11X,GYG1,RASSF8,AGBL5,ICA1,KCNA2,KCNB1,KCNK2,STMN1,MYO9A,NAP1L1,NPTX2,NUCB2,PDGFRA,RETREG1,SNRK,C1orf109,RYR3,PEX26,TACR1,KAZN,WWC1,WDR7,CYB561A3,ERCC6L2,TPD52,AMOT,ZNF74,NAV3,PDSS2,IFT88,NETO1,RNF146" MicroRNA hsa-miR-382-3p:TargetScan hsa-miR-382-3p TargetScan 1.06E-18 5.96E-15 2.04E-18 1.88E-17 46 194 "CSMD3,PTCHD1,BEND6,OGT,APBB2,APP,JAZF1,BTRC,CA12,CCNT1,AIFM1,DNAJC6,PLEKHM1,EGR3,KCTD3,FOXO3,FUT9,AHCYL1,FAXC,NFU1,GPR75,GRM5,ARHGAP19,LRRTM3,KCNH1,KCNN3,GPR155,HS6ST3,MXI1,MYO9A,NFYA,NOVA1,PAX6,PBX1,PDPK1,FTO,OCIAD1,RBBP6,NLGN1,CMTR2,FAM126B,LMO3,ACSBG1,R3HDM1,NETO2,CPNE4" MicroRNA hsa-miR-6852-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-18 6.74E-15 2.31E-18 2.13E-17 50 228 "AS3MT,ARHGDIA,SLC4A4,CBS,DIS3L,BTF3L4,CSNK1E,PLXNA4,ZBTB24,KLHL3,RABGAP1L,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,NCKAP1,KDM2B,CNDP1,LILRA2,GPR26,SCRG1,KCNK1,CHST6,MOG,SAMD5,OLR1,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,BDP1,FNBP1,CLUAP1,LHFPL4,ALG1,AGTPBP1,CLASP1,ARL10,CBX5,PARD3,SSBP2,KLC2,ZBTB16,RNF170" MicroRNA hsa-miR-409-5p:PITA hsa-miR-409-5p:PITA_TOP PITA 1.24E-18 6.96E-15 2.38E-18 2.19E-17 32 93 "KCTD16,OSBPL8,ARHGAP5,DPY19L3,SYNJ1,PUM1,DBT,DNAJC6,KMT5B,RRAGB,STAU2,PHYHIPL,STAG2,PPARGC1A,GPM6A,ADAMTS6,KLF12,KCNA1,KCNK1,USP47,LGI2,FAM214B,EPB41L3,RPGRIP1L,SLC44A1,TRPC1,TRPS1,VLDLR,KLC2,ZIC1,ZIC3,LRP8" MicroRNA hsa-miR-6504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-18 7.25E-15 2.48E-18 2.28E-17 65 367 "CLK4,NLGN4X,TAOK1,ALAD,APP,ATM,SLC2A11,BACH1,LDHD,CD81,PLAA,LETMD1,CSNK1E,UBXN2A,USP6NL,ZC3H11A,RABGAP1L,SLC12A6,ABI2,EIF4G2,MRNIP,TUBA1B,CEP78,GTF2IRD2,ZNF44,TRAF3IP2,TXNL4A,DIDO1,KIF3A,ZDHHC15,NKD1,ZIC5,IL6R,METTL21A,KCND3,CYP27C1,SFXN5,MBD1,CHST6,SESN3,MYCN,PABPC1L2A,NAP1L1,ZNF426,MINDY2,PPP2R5E,OCIAD1,SETD5,C12orf49,FOXRED2,HSPA4L,SLC12A2,TMCC1,FAM126B,SP2,TROVE2,INKA2,DIP2A,ZMAT3,CBX5,PARD3,RPL7L1,ZNF70,MPPE1,FXR1" MicroRNA hsa-miR-1229:PITA hsa-miR-1229:PITA_TOP PITA 1.31E-18 7.38E-15 2.52E-18 2.32E-17 34 106 "APC,ASCL1,ATP2B2,CADM3,RUNX1T1,DLG2,EIF4G2,AFF2,GABRG2,GRIA2,RNF165,KLF12,CELF5,C5orf24,ITGAV,KCNA1,MATN2,CNOT4,PDE4D,PDGFRA,ZFHX4,RTN1,PPM1E,ZNF430,SLC12A2,RIMS1,SNCA,SOX5,ZCCHC24,CADM1,UBE3A,PRDM8,WNK3,SOCS4" MicroRNA hsa-miR-548am-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-18 7.62E-15 2.60E-18 2.40E-17 57 291 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548ah-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-18 7.62E-15 2.60E-18 2.40E-17 57 291 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-412:PITA hsa-miR-412:PITA_TOP PITA 1.40E-18 7.88E-15 2.69E-18 2.48E-17 39 141 "FMNL2,HECW2,SEMA6A,PKP4,NCOA1,BTRC,FMNL3,CDH10,QKI,CREB5,SLITRK5,ELMSAN1,SMG7,DYRK1A,APH1A,MBNL2,TAOK3,STAG2,SPIN1,GPD2,RNF165,SLC6A17,NEUROD2,ZNF827,SNRK,ROBO1,SATB1,SOX6,NLGN1,WDTC1,KIF21B,PEG10,NKAIN2,ERBIN,EXOC7,TMEM237,POLR3H,CSDE1,ST8SIA2" MicroRNA hsa-miR-4793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-18 8.21E-15 2.80E-18 2.58E-17 70 418 "XKR4,SLC24A4,HACE1,KIAA1324,WDR35,TXNDC16,AK2,PHF12,AMER3,AQP6,CDC14B,ZNF555,SLC16A4,ZNF445,NRXN3,COL9A2,CRY2,SUSD5,SOCS5,UBXN2A,TMEM170A,DNAL1,HP1BP3,MTX3,EPB41,KATNAL1,ATP13A4,ANKFY1,FUT9,ZNF234,DBF4,GPR75,KIAA1958,NR3C1,KIF3A,MFSD2A,DOCK7,KCNN3,CHST6,CCDC80,PABPC1L2A,ZC3H12B,SLC11A2,GPR137C,STK32A,TMEM145,ZNF844,KLHL11,ALG9,ATAT1,IL17RB,MAGI3,SEPHS1,ANKRD36,ZHX3,EMC1,MCF2L2,C3orf70,TCF7L2,ARL10,PPIL6,SSBP2,ZNF610,UBC,USP1,PLPP4,SLC30A4,TRIM16L,HNRNPA3,GAN" MicroRNA "AACATTC,MIR-409-3P:MSigDB" "AACATTC,MIR-409-3P:MSigDB" MSigDB 1.50E-18 8.44E-15 2.88E-18 2.65E-17 38 134 "NDRG3,OGT,SRSF11,QKI,NIPBL,CLOCK,CREB5,AKAP12,CTNND1,HDAC4,TOX,MATR3,MTX3,EDN1,IP6K2,MSTN,GPD2,FICD,BACH2,HNRNPK,IGF1,KCNMA1,GPR88,PCDH9,PDE4B,CDK14,GDAP1L1,SCHIP1,RIC8B,PBRM1,SEMA6D,SOX6,USP33,ELOVL4,PUM2,TGFBR3,TPM3,TBC1D15" MicroRNA hsa-miR-6851-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-18 8.68E-15 2.96E-18 2.73E-17 62 339 "ABCF1,HACE1,ANK1,ASPH,DOCK11,FOXK1,DDR1,PTBP2,CBS,ACBD5,PITPNM3,NOS1AP,GAPVD1,KIAA0513,SIRPA,DNAL1,HP1BP3,DUSP9,APH1A,MRO,FGFR1,LILRA2,SHISA6,IGF1,SLC6A17,MXI1,NAP1L1,FXYD6,TBC1D25,PKM,SMOX,EPN1,FAT3,PPARA,CNNM2,NCR3LG1,MTMR10,CEP97,PLEKHB2,RAP1GDS1,PGBD4,NCBP3,AMBRA1,SLC2A5,EPN2,KIF13A,SOX11,UNC5B,CDK19,DDN,AGTPBP1,SLC19A3,WBP2,SSBP2,BCL2L13,LAT2,ZNF17,SMARCAD1,EVI5,CIAPIN1,PARP11,SSPN" MicroRNA hsa-miR-6739-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-18 8.76E-15 2.99E-18 2.75E-17 47 204 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,GPR61,BSCL2,WAC,PRRC2B,NEGR1,KCNB1,MAOB,SESN3,JAKMIP3,OCRL,ZNF827,PDGFRA,EPN1,TNPO2,POU3F2,WBP1L,BDNF-AS,RAB3A,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,RPH3A,PEX26,YPEL4,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,ZFP91,NR2E1,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-6892-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-18 8.76E-15 2.99E-18 2.75E-17 47 204 "ACTN2,ARRB1,ATP2B1,ZBED1,CDH8,GPR37L1,STOML1,CRY2,RGS6,PITPNM3,UBXN2A,PLCXD3,CYBB,MYADM,FRMPD4,PHF19,TMEM170A,RUSC2,ST8SIA3,HIPK3,HEYL,EMX2,ZNF391,FER,DKK3,GPR75,GLUL,ZNF638,GRID1,SHISA6,C2CD4C,NODAL,KSR2,OLR1,ZDHHC22,PFKFB3,PTPRG,ASIC4,GALNT10,CLUAP1,TMEM151B,KCNK12,DPYSL5,SLC30A3,VANGL2,FRMD6,JPH3" MicroRNA hsa-miR-548j-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-18 9.00E-15 3.07E-18 2.83E-17 57 292 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-596:PITA hsa-miR-596:PITA_TOP PITA 1.79E-18 1.00E-14 3.42E-18 3.15E-17 32 94 "GPR158,SEMA6A,CNIH2,DDX3Y,BCL2L2,JAZF1,TRIM41,CANX,CBARP,PHACTR3,ERC2,FBXL5,SMG7,CHRDL1,DPYSL2,DTNB,EGR3,AGAP3,ELOVL5,NEGR1,MYLK2,HMGCLL1,RAB3IL1,FAM102A,SOX10,SP4,NCDN,ZFP91,TRIM9,CELF4,NAV3,ST8SIA2" MicroRNA hsa-miR-423-5p:TargetScan hsa-miR-423-5p TargetScan 1.86E-18 1.04E-14 3.55E-18 3.27E-17 41 157 "ACHE,PITPNM2,MARK4,CADM3,AZGP1,FMNL3,NUMBL,DLGAP3,NRXN2,RIMS4,KLHL3,EFNA3,ELAVL3,ERBB2,PCYOX1,AGAP2,GLYR1,RFFL,GRM1,RNF165,KAT7,NFIX,NNAT,NUCB1,PAK3,PDE1B,PKIA,BCAS3,RAB5B,GAL3ST4,AMBRA1,NMNAT2,MPRIP,FAM168A,PLCB1,CNTN2,FBXL16,CBX5,DAAM2,RPRM,KLC2" MicroRNA hsa-miR-548aq-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-18 1.06E-14 3.62E-18 3.33E-17 57 293 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548aj-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-18 1.06E-14 3.62E-18 3.33E-17 57 293 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548ae-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-18 1.06E-14 3.62E-18 3.33E-17 57 293 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-548x-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-18 1.06E-14 3.62E-18 3.33E-17 57 293 "ARID1A,TMCC3,ZNF608,KIAA1324,TRMT9B,AMPD3,PHF12,CDC14B,ARNTL,ZBTB10,ZNF583,MTMR3,RIMS4,PLXNA4,PHF19,CELSR3,MRO,SYNCRIP,SEMA4D,APOPT1,UFM1,GABRB3,GATM,FAXC,NUDT21,GRIK4,FRMD5,HMGB1,IL6R,MEF2C,CTNNA3,MYBPC1,MYO6,KCNK10,PDGFRA,PSAT1,PPP2R5E,KANSL1,PKIA,PKN2,PTPRB,PTPRG,ZYG11B,TMLHE,EXD2,BTBD3,ATF7IP,SNCB,FAM126B,KIF1B,ALG1,TGFBR3,HHIP,TJP1,ZIC2,MKRN3,NHSL1" MicroRNA hsa-miR-1306-5p:TargetScan hsa-miR-1306-5p TargetScan 1.93E-18 1.08E-14 3.68E-18 3.39E-17 47 205 "ABCF1,NDRG2,GOLGA7B,APC,KIAA1614,ATP1A2,MTMR9,BCL2L2,BCL7A,DDR1,LDB2,FMNL3,GPR37L1,CTH,KLHL3,FAM57B,RCAN1,ABI2,ELAVL3,EIF1,APC2,RCSD1,INSM2,BTN2A1,KCND3,MEIS1,MOBP,KCNK10,PDE4A,PFKFB3,GDAP1L1,PLXNB1,PPP5C,PTAFR,PBRM1,RIMKLA,MYT1L,RAP1GAP2,COLGALT2,ARL10,CBX5,HEY2,RASD2,FRRS1L,CAB39L,RGS7BP,PIANP" MicroRNA hsa-miR-1322:PITA hsa-miR-1322:PITA_TOP PITA 1.99E-18 1.12E-14 3.80E-18 3.50E-17 38 135 "XKR4,HECW2,LRCH2,ARNTL,CACNA2D1,CDC42,CLTC,HS3ST4,GOLGA7,COPS4,TOMM40L,SORBS1,GPM6A,GRIK2,KLF12,BACH2,KCND1,KIF5A,CHIC1,MEIS1,MYO5A,PDE1C,OXR1,SATB1,CSRNP3,PEG10,CDK19,PLCB1,SYPL1,CAMTA1,UNC5D,TCF7,SLC44A1,FAM155A,PCDH20,TMEM237,CADM2,HRASLS" MicroRNA hsa-miR-1260:PITA hsa-miR-1260:PITA_TOP PITA 2.01E-18 1.13E-14 3.83E-18 3.53E-17 42 165 "ADCY6,CDC42BPA,ATP2B1,PTBP2,CDH2,SOCS6,NRXN2,HECTD1,ZNF385A,CRY2,PLCXD3,ALKBH8,SRGAP3,DLG2,DYRK1A,GPR61,ELAVL3,EPB41L1,ETV1,SUCO,NPTN,GAB1,GABRA4,PPARGC1A,HNRNPK,NEXMIF,NFIX,NUMA1,CAMKV,FAM120C,RXRA,NCBP3,AMBRA1,CPEB4,NMNAT2,CDK19,VAMP1,ZIC1,EMSY,STMN4,FXR1,RNF146" MicroRNA hsa-miR-331-3p:TargetScan hsa-miR-331-3p TargetScan 2.01E-18 1.13E-14 3.83E-18 3.53E-17 42 165 "CSMD2,RNF150,AP2A1,CASK,ARRB1,NRP2,KSR1,HAP1,DLGAP3,DNAJB5,IGLON5,MYRIP,RIMS4,ECE2,ELMSAN1,FAM135B,PHC2,ELN,PLEKHO1,ANKRD13B,FGF11,CPLX2,GPR26,GRIK3,ATOH8,LRRC4B,CHIC1,MEIS1,MEIS2,MSI1,MDGA1,NEUROD2,NOVA2,PTPRD,C1orf109,RAB5B,RIC8B,CASC3,ANKRD6,EXOC7,FAM208A,POLR3H" MicroRNA hsa-miR-6887-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-18 1.20E-14 4.07E-18 3.75E-17 44 181 "ACTN2,SLC12A5,PNMA8B,AK2,LRFN1,ARRB1,ASPA,GPR146,NIPA1,FOXK1,PNKD,SH2B1,CYBB,PHF19,KIF26A,EPB41L1,DKK3,SEPT9,GBX2,FAM107A,PADI2,SHISA6,METTL21A,KCNJ10,CYP27C1,CTNNA3,VWA2,RDX,GTDC1,SETD5,ZFP1,SMARCE1,ZHX3,INKA2,NSFL1C,TMEM151B,THRA,C5orf64,TNS1,RPRM,MGAT5B,ZNF24,URM1,PPP1R3F" MicroRNA hsa-miR-4772-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-18 1.29E-14 4.39E-18 4.05E-17 61 332 "MTA3,GPR158,SPOP,USP37,KIAA1614,BMP7,GYG2,FOXK1,MAP7,DIS3L,RTTN,HINFP,FGFR1OP2,MATR3,KRBA2,HEYL,IRAK4,MRNIP,IGSF6,SRARP,MED12L,FGFR1,SEC23B,APOPT1,DBF4,KDM2B,RAB40B,CNDP1,LILRA2,RFFL,DDX19B,HMGB1,ZNF546,IBA57,METTL21A,GPR155,MAPT,MOG,PDGFRA,ZNF655,A2ML1,EXOSC10,FITM2,SNRK,MTMR10,NWD1,PGBD4,PEX26,ZNF430,ATF7IP,MAPKBP1,SP2,ZNF621,INKA2,KLHL7,ALG1,PCDHA6,ZNF106,ZNF384,SSBP2,LINC00632" MicroRNA hsa-miR-6733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-18 1.42E-14 4.81E-18 4.43E-17 46 198 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,GPR61,BSCL2,WAC,PRRC2B,NEGR1,KCNB1,MAOB,SESN3,JAKMIP3,OCRL,ZNF827,PDGFRA,EPN1,TNPO2,POU3F2,WBP1L,BDNF-AS,RAB3A,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,RPH3A,PEX26,YPEL4,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,ZFP91,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-3153:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-18 1.42E-14 4.81E-18 4.43E-17 46 198 "OGT,CCAR2,LDHD,AP1M1,ZBED1,CACNA2D2,RTTN,DPP6,GPR61,BSCL2,WAC,PRRC2B,NEGR1,KCNB1,MAOB,SESN3,JAKMIP3,OCRL,ZNF827,PDGFRA,EPN1,TNPO2,POU3F2,WBP1L,BDNF-AS,RAB3A,SH3TC2,RAP1GDS1,SLC25A36,C12orf49,KIAA0895L,NCBP3,RPH3A,PEX26,YPEL4,COA1,POGZ,SSTR1,NXT2,IQCE,ARL10,NACC2,ZFP91,RGMB,MGAT5B,GAN" MicroRNA hsa-miR-6821-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-18 1.55E-14 5.24E-18 4.83E-17 56 286 "AS3MT,TAOK1,PHF12,MTMR9,CACNB2,VXN,STOML1,ENTPD4,MYADM,DBT,BLOC1S6,CHRDL1,RGS17,SEC24B,BRPF3,SRCAP,GPR26,HAS2,DDX19B,HMGB1,ATCAY,C2orf72,IL6R,KCNN1,KCNN3,MAN2A2,MBNL1,CHST6,P2RX7,TMOD2,PIK3C2A,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,UEVLD,HSPA4L,NUBPL,ZNF430,SLC15A2,ANKRD36,FAM126B,CLUAP1,KIF1B,ZBTB43,SSTR2,STAC2,KLHL7,ZNF34,USP1,MEAF6,ZNF708,GAN,SPATA13" MicroRNA hsa-miR-1231:PITA hsa-miR-1231:PITA_TOP PITA 2.77E-18 1.56E-14 5.27E-18 4.86E-17 40 151 "ACTN1,AMPH,GPAM,JAZF1,BTRC,REPS2,NRXN3,QKI,GAPVD1,FRMPD4,IP6K1,CTIF,EFNB3,ANKRD13B,FGF14,PSIP1,SYNPO,KCNA1,MEIS2,GIT1,NEFM,NOVA1,NTRK2,GPR88,PACSIN1,QRICH1,FAM120C,HUNK,NTNG1,SLC6A1,RCOR3,SOX11,SMG6,TIAM1,SLAIN1,WIPF1,SF1,CELF4,MSRB3,SOCS4" MicroRNA hsa-miR-25-3p:Functional MTI Functional MTI miRTarbase 2.86E-18 1.61E-14 5.44E-18 5.01E-17 79 518 "SLC12A5,CASKIN1,USP28,ATP2A2,CDK5R1,SYNPR,CLTA,TMEM184B,SLC4A7,SNPH,DCTN1,HP1BP3,ATN1,DNM1L,MRO,EIF4G2,PLEKHA1,EIF1,ERBB2,DENND4A,NRN1,PRMT5,FECH,KIAA1109,SEMA4D,MPP6,ACSS1,TUBGCP4,KIAA1958,PRRC2B,LILRA2,TPPP,RAPGEF1,AGBL5,HSP90AA1,SMAP1,EID2B,C5orf24,ZIC5,RBPJ,IL6ST,MBD1,SESN3,CNOT4,ZDHHC8,PIK3CD,CCSER2,ZFYVE21,KCTD15,PURG,TNPO2,TATDN3,UHRF1BP1,MTMR10,PEX5,REV3L,RGS3,SLC25A36,ROBO1,FBXW7,FNIP1,CPEB3,SLC12A4,BTBD7,ATF7IP,CPEB4,FNBP1,SOX11,MCF2L2,ITPRID2,STXBP1,ANKRD24,CABIN1,RBFOX2,ZNF346,ZNF24,PMEPA1,MFF,XKR7" MicroRNA hsa-miR-345:PITA hsa-miR-345:PITA_TOP PITA 3.11E-18 1.75E-14 5.92E-18 5.45E-17 33 102 "BSN,USP6,KMT2C,RAB39B,RBM12,KMT5B,EPS8,SORBS1,GABRA4,CELF3,USP54,OLFM3,SMAD1,KITLG,MYO5A,SLC11A2,PDE4B,MED1,FAM120C,RIPOR1,FIGN,PBRM1,PPM1E,CPEB3,FAM214B,SSTR2,SYT4,FBXW11,TCF4,HEY2,TRPS1,SSBP2,FRMD6" MicroRNA hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA_TOP PITA 3.25E-18 1.83E-14 6.18E-18 5.69E-17 42 167 "SDE2,TMEFF1,DDX3Y,SPAG9,CDC42,DLGAP2,CFL2,CNR1,CLOCK,CTNND2,DSCAM,EGR3,ERBB4,ZIC4,NBEA,CAMKK2,PCDH17,TNRC6A,TDRKH,GRIN1,IPO5,NCOA7,MEIS1,MSI1,NKX2-2,PDE4D,WBP1L,FAM120C,RIC8B,SOX6,NAPB,ZCCHC24,LARP4,TTBK2,SYT4,TCF12,FRYL,SIRT1,TIAM1,TSN,CADM1,SMARCAD1" MicroRNA hsa-miR-122-5p:TargetScan hsa-miR-122-5p TargetScan 3.25E-18 1.83E-14 6.18E-18 5.69E-17 42 167 "NDRG3,CANX,CDC42BPB,CRY2,CS,CTNND2,ECE2,ARHGAP32,G3BP2,DLG2,PLEKHO1,ERBB4,CD320,FGF1,FOXO3,ATP6V1H,IGSF5,BACH2,NEGR1,MBNL1,MEIS2,GIT1,MYO9A,DDR2,PAK3,PKM,MASP1,PTPRB,PLEKHB2,RIMKLA,SATB1,RIMS1,PEG10,NPAS3,RAP1GAP2,HIF3A,DICER1,HHIP,BEST1,MICU3,CADM2,RGMA" MicroRNA hsa-miR-510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.25E-18 1.83E-14 6.18E-18 5.69E-17 42 167 "FAM43B,SLC24A4,MARCH3,COPB2,SRSF11,MFSD4A,C2CD2,LIN54,ELAVL4,SYNCRIP,SGIP1,GPR75,GRM5,SHISAL1,IL6R,KCNJ4,ARHGAP12,MAT2A,TM6SF1,PAX6,PSAT1,MINDY2,PPP2R5E,CEP97,SH3TC2,SETD5,FBXW7,CSRNP3,CPEB4,INAVA,SON,FNBP1,MCF2L2,AJAP1,C3orf70,ATMIN,ZFP91,RUNDC3B,TRPS1,ZNF610,UBC,SPATA13" MicroRNA hsa-miR-615-5p:mirSVR_highEffct hsa-miR-615-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.43E-18 1.93E-14 6.51E-18 6.00E-17 60 325 "SYN3,SYS1,AMH,DDR1,TBRG4,PLEKHB1,RAB33A,LETMD1,ABI3BP,SMARCAL1,CLIP3,CS,SNCAIP,DNAJC6,MYEF2,DMPK,DMTF1,CELSR3,ELN,HSPA12B,TUBB4A,SUCO,SYT3,APOPT1,USP19,LILRB4,GRIK5,ADAMTS8,MAN1B1,NKD1,ZNF678,ITGA7,CAMK2N2,LRP1B,MEIS2,STK32C,MT1M,NCAM1,PDGFRA,TMEM38A,PLTP,PPP5C,PRKCZ,MAPK10,MASP1,PEX5,RGS4,PKNOX2,ZSCAN29,CEP68,C12orf76,SATB2,RNF216P1,ITGB3BP,CDH22,TPM3,STXBP4,HSPBP1,MEIS3,PRDM8" MicroRNA hsa-miR-891a:mirSVR_highEffct hsa-miR-891a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-18 1.94E-14 6.57E-18 6.05E-17 38 137 "NCKAP5,XKR4,TAOK1,ADGRF5,CHID1,RGS9,AP1M1,MTMR7,CHM,SYNPR,DAPK1,HS3ST2,MBNL2,FGFR1,SGIP1,SLC37A3,NOP56,NSG2,ST6GALNAC3,OGA,KIAA1958,SOX21,NPTX2,TMEM260,OCIAD1,RGS7,EXD2,CARF,DHX30,MYT1L,DIP2A,VAMP1,TMPO,FAM155A,PLEKHH2,FMN2,ADAMTS9,SLC4A10" MicroRNA hsa-miR-3135b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.47E-18 1.95E-14 6.59E-18 6.07E-17 67 394 "ABCF1,AS3MT,XKR4,ADCY2,RNF157,ESYT2,ISPD,ENTPD4,CSF1,DBT,KRBA2,E2F6,HEYL,OPTN,BSCL2,TUBD1,SEC23B,CINP,SPECC1,PNMA2,SRCAP,GPR75,PRRC2B,CNDP1,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,ZFYVE27,MKLN1,MMP17,MYCN,ZNF713,GPR137C,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,ZYG11B,ROBO1,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,ANKRD36,ERC1,SSTR2,MPRIP,APOM,KLHL7,ALG1,VWC2,GPRIN3,GPR161,ZNF34,MEAF6,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2" MicroRNA hsa-miR-4775:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-18 2.05E-14 6.93E-18 6.38E-17 57 297 "SYT13,USP37,SLC7A14,KIAA1614,CACNG1,PTBP2,SLC24A2,LETMD1,RIMS4,MYADM,CEP170,FARSB,RASA4,C8orf37,EPB41L1,RAB9B,NCALD,RTN3,WAC,AMOTL2,SEC23B,PCYOX1,SGIP1,DKK3,NCKAP1,PPARGC1A,MALT1,ZNF276,PCDH11X,KIAA1958,PRRC2B,GRIK4,KLF12,PAXBP1,GPR155,MBNL1,TM6SF1,MXI1,NUCB1,PLCL1,SH3KBP1,MAPK8,FAM161B,SLC8A1,PALLD,GSE1,AGTPBP1,KIAA0930,SSBP2,TUB,NSD2,ZFP37,KCNT2,WNK1,LINC00632,ZDHHC20,SSPN" MicroRNA "CAGCCTC,MIR-485-5P:MSigDB" "CAGCCTC,MIR-485-5P:MSigDB" MSigDB 3.69E-18 2.07E-14 7.01E-18 6.45E-17 37 130 "SYN3,LRRC7,SEMA4G,CCAR2,TAOK2,NGEF,QKI,CNTFR,ARHGAP32,NBEA,GABRB3,PPARGC1A,TTBK1,GRIN1,RNF165,KCNA6,KCNJ11,TTYH2,CAMK2N2,MDGA1,NOVA1,NUCB1,CDK18,PLEC,POU6F1,CHD9,ELMO2,ANKFN1,TMCC1,WDTC1,SOX5,SPTB,ZFP91,SF1,HPS4,WNK3,NELFE" MicroRNA hsa-miR-181d-5p:Functional MTI Functional MTI miRTarbase 3.84E-18 2.16E-14 7.28E-18 6.71E-17 56 288 "SLC25A25,MTUS1,HECW2,HFM1,MARCH4,ARRB2,CAPRIN2,ATM,ATP2B1,NMT2,PNKD,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,G3BP2,MTX3,FSD1L,FAM13A,EN2,STX2,EPS8,IQCG,GAB1,MALT1,DHRS4,HMGB1,ZDHHC15,IPO5,NCOA7,BLOC1S2,NRDC,PPP2R5E,ZNF844,PBRM1,MEG3,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,CPEB4,ZNF667,ZNF415,TMCC1,UNC5B,PRRC2C,MGRN1,SLC35G2,TUBB2A,ZNF781,NSD2,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-3689d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-18 2.20E-14 7.42E-18 6.83E-17 63 355 "ABCF1,HACE1,ANK1,ASPH,DOCK11,FOXK1,DDR1,PTBP2,CBS,ACBD5,PITPNM3,NOS1AP,GAPVD1,KIAA0513,SIRPA,DNAL1,HP1BP3,DUSP9,APH1A,MRO,COQ7,FGFR1,LILRA2,SHISA6,IGF1,SLC6A17,MXI1,NAP1L1,FXYD6,TBC1D25,PKM,SMOX,EPN1,FAT3,PPARA,CNNM2,NCR3LG1,MTMR10,CEP97,PLEKHB2,RAP1GDS1,PGBD4,NCBP3,AMBRA1,SLC2A5,EPN2,KIF13A,SOX11,UNC5B,CDK19,DDN,AGTPBP1,SLC19A3,WBP2,SSBP2,BCL2L13,LAT2,ZNF17,SMARCAD1,EVI5,CIAPIN1,PARP11,SSPN" MicroRNA hsa-miR-744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-18 2.24E-14 7.56E-18 6.96E-17 71 436 "DPF1,PLEKHG5,AP2A2,GPRASP2,PRX,PDXK,ARHGAP5,ARHGDIA,MARCH3,ZSCAN18,CACNA1A,ARHGEF2,CDC25B,MICAL2,CHD5,MATR3,IP6K1,SEC16A,NR1D2,FARSB,PHC2,EEF1A2,EIF4G1,SORBS3,EN2,MTSS1L,TUBA1B,RACK1,FGFR1,HPCAL4,FOXO3,TMEM175,USP21,DISC1,GART,SRCAP,GFER,TDRKH,DIDO1,ATXN2L,NKD1,TJAP1,STMN1,LIMS1,LDLRAD3,NEUROD2,NFIX,NRGN,PDE4A,PDPK1,EPN1,MAPK7,PXK,PTGR2,FOXRED2,SALL1,SBF1,WDR37,ATF7IP,ZCCHC24,INKA2,SYPL1,ATP11A,MGRN1,ATMIN,TIAM1,WBP2,TSC2,TUB,INTS3,TUBA1A" MicroRNA hsa-miR-616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-18 2.26E-14 7.62E-18 7.02E-17 65 375 "TMEM132B,SLC24A4,TXNDC16,MAP7,ZBED1,ZNF445,GPR37L1,NRXN1,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,RABGAP1L,MTX3,FEM1B,ELAVL2,PLEKHA1,ELAVL4,C8orf37,COQ7,FAXC,SRCAP,RNPS1,TNRC6A,FUT10,RFFL,PTGDR2,DDX19B,ARHGAP12,CHST6,MITF,DBNL,OLR1,PIK3C2A,CCSER2,ZNF426,MAPK8,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,UNC80,FNBP1,SP4,KIF1B,ADAMTS17,TMEM136,TCF7L2,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,AMOT,TOM1L2,VLDLR,TBC1D15,ZNF24,WIPF2" MicroRNA hsa-miR-483-3p:Functional MTI Functional MTI miRTarbase 4.22E-18 2.37E-14 7.99E-18 7.36E-17 43 176 "ADCY6,KCTD16,PHF12,ATP2B1,DPY19L3,CAMK2G,C2CD2,SUSD5,KIAA0408,FRMPD4,DBN1,RCAN1,RASA4,DLC1,SLC37A3,SMC2,ZNF274,RAPGEF1,HPR,IGF1,TJAP1,FGFBP3,KSR2,GPR137C,BEST3,ZNF426,RAB5B,RASGRF1,GTDC1,BTBD3,PALLD,ZHX3,UNC5B,EXOC7,USP22,TMEM151B,PARD3,RUNDC3B,PLEKHH2,AGMO,CRB2,DPYSL5,DHX33" MicroRNA hsa-miR-378a-3p:TargetScan hsa-miR-378a-3p TargetScan 4.99E-18 2.80E-14 9.45E-18 8.70E-17 41 161 "ADD2,PTCHD1,CDC42BPA,C6orf89,ALS2,EIF4G3,BCL2L2,KSR1,MROH8,RIMS4,FRMPD4,CALN1,DSCAM,DYRK1A,ABI2,MED12L,FOXG1,CAMKK2,AP4B1,GRIK3,PTPRT,GSTM5,IL1RAPL1,IGF1,IL6ST,KCND1,KIF2A,NEUROD1,NOVA2,PDE1B,PDPK1,PEX2,RASGRF1,AP1AR,CSRNP3,IQSEC2,NSFL1C,PSD3,ARL10,CBX5,LAS1L" MicroRNA hsa-miR-4321:mirSVR_highEffct hsa-miR-4321:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-18 2.97E-14 1.00E-17 9.21E-17 27 67 "PTCHD1,RTL9,PDXK,MTMR2,CFAP61,ARMCX4,FAM57B,DYRK1A,STAU2,FYB1,GALNT15,DISC1,GHR,TXNL4A,DIDO1,MARK1,PCDH18,RORB,RPL15,MEG3,RAB3GAP1,TET1,STOX1,MTCL1,TBX15,WDR7,TRO" MicroRNA hsa-miR-181c-5p:Functional MTI Functional MTI miRTarbase 6.28E-18 3.53E-14 1.19E-17 1.10E-16 56 291 "SLC25A25,NDRG2,MTUS1,HECW2,HFM1,ARRB2,CAPRIN2,ATM,ATP2B1,NMT2,PNKD,OSBPL3,SIPA1L1,DCAF4,LONRF1,ELMSAN1,G3BP2,MTX3,DPYSL2,FSD1L,FAM13A,EN2,STX2,EPS8,IQCG,ZDHHC15,KIT,IPO5,NCOA7,BLOC1S2,PPP2R5E,ZNF844,UBR7,PBRM1,FAM192A,ATXN7,SCN8A,CHD9,FBXO11,BTBD3,CPEB4,ZNF667,ZNF415,TMCC1,UNC5B,PRRC2C,TRIM2,SLC35G2,SIRT1,TUB,TUBB2A,ZNF781,NSD2,ZNF23,SPIRE1,EMSY" MicroRNA hsa-miR-224-5p:Functional MTI Functional MTI miRTarbase 6.47E-18 3.63E-14 1.22E-17 1.13E-16 37 132 "SLC12A5,API5,SLC7A14,VXN,LONRF2,CDC42,QKI,USP6NL,SEC14L5,TOMM20,DPYSL2,EDNRA,HIPK3,FEM1B,CACNG7,EFNA3,COQ7,RAB9B,F3,ZNF585B,GORAB,NPTN,TNRC6A,ADAP1,RASSF8,HSP90AA1,MITF,PTX3,C12orf49,RPL15,FRYL,ITGB3BP,KCTD2,TPD52,TOM1L2,WRN,XPO1" MicroRNA hsa-miR-6790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.59E-18 3.70E-14 1.25E-17 1.15E-16 55 282 "AS3MT,TAOK1,PHF12,MTMR9,FOXK1,CACNB2,VXN,STOML1,ENTPD4,MYADM,DBT,BLOC1S6,CHRDL1,SEC24B,SRCAP,GPR26,HAS2,DDX19B,HMGB1,ATCAY,C2orf72,IL6R,KCNN1,KCNN3,MAN2A2,MBNL1,CHST6,AFF1,P2RX7,TMOD2,PIK3C2A,PIGG,NCR3LG1,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,UEVLD,HSPA4L,NUBPL,ZNF430,SLC15A2,ANKRD36,FAM126B,CLUAP1,KIF1B,ZBTB43,SSTR2,STAC2,KLHL7,ZNF34,USP1,MEAF6,ZNF708,GAN" MicroRNA hsa-miR-324-5p:TargetScan hsa-miR-324-5p TargetScan 6.64E-18 3.73E-14 1.26E-17 1.16E-16 34 111 "HECW2,PCDH19,CDC42BPA,APP,LDLRAD4,CCNT1,CLCN4,NIPBL,PCYT1B,NRG2,NCAN,KIAA0513,DBN1,DLG4,RCAN1,C3orf18,FYN,GGT7,GRIK3,FAM19A2,ARHGAP36,CHIC1,MGAT3,PBX1,CAMKV,GON4L,PTPRD,LGI2,FBXO11,NAPB,KAZN,RBFOX2,HNRNPA3,GAN" MicroRNA hsa-miR-4500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.82E-18 4.95E-14 1.67E-17 1.54E-16 58 312 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,FMNL3,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,PLEKHO1,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,SALL3,DISC1,GATM,POLL,FUT10,RABL2A,IL6R,KPNA5,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,TGFBR3,CBX5,RBFOX2,TUBB2A,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-4458:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.82E-18 4.95E-14 1.67E-17 1.54E-16 58 312 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,FMNL3,CRY2,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,PLEKHO1,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,SALL3,DISC1,GATM,POLL,FUT10,RABL2A,IL6R,KPNA5,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,TGFBR3,CBX5,RBFOX2,TUBB2A,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-let-7g-5p:Functional MTI Functional MTI miRTarbase 8.85E-18 4.97E-14 1.67E-17 1.54E-16 61 341 "FZD9,MTUS1,ZNF578,AQP6,IGDCC4,BACH1,DDR1,FMNL3,CRY2,DCAF8,DNAL1,MTX3,DNAH9,E2F6,EDN1,ANKRD46,EIF4G2,PLEKHO1,TUBB4A,TOMM40L,TRMO,PDLIM5,CELF1,SALL3,DISC1,GATM,POLL,FUT10,RABL2A,HMGB1,IL6R,KPNA5,NAT8L,MDM4,THYN1,NAP1L1,SLC11A2,NUCB2,OPRL1,QDPR,USP47,RDX,FIGN,ATXN2,KIF27,FNDC3A,PEG10,MCF2L2,FNDC9,SYT1,KIAA0930,SLC19A3,NSD1,AHCYL2,TGFBR3,CBX5,RBFOX2,TUBB2A,ZNF28,SMARCAD1,C12orf4" MicroRNA hsa-miR-382-5p:TargetScan hsa-miR-382-5p TargetScan 8.86E-18 4.98E-14 1.67E-17 1.54E-16 39 148 "GALNT13,GPR158,CASKIN1,CDK13,BACH1,P2RX6,JAM2,CLTC,HIPK3,PLXNC1,ELAVL4,EN2,AMOTL2,GABRA4,GABRB3,FAM184B,IL1RAPL1,SCRG1,HNMT,NEGR1,METTL21A,KCNQ3,LSAMP,GPR155,MBNL1,MMP16,SAMD5,PDPK1,LRP12,RASGRF1,RPE,CPEB3,BTBD3,BTBD7,ARHGEF12,DICER1,HHIP,NAV3,GAN" MicroRNA hsa-miR-7151-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.88E-18 4.99E-14 1.68E-17 1.54E-16 67 401 "CLK4,ESYT2,TAOK1,ATM,ATP1B3,SLC2A11,LDHD,ZMYM4,DIS3L,PLAA,BTF3L4,LETMD1,RNF14,SOCS5,KBTBD11,SLC12A6,ABI2,EIF4G2,IRAK4,MRNIP,TUBD1,COQ7,SLC43A2,TUBA1B,CEP78,FDFT1,GTF2IRD2,ZNF44,GABRB1,TRAF3IP2,TXNL4A,RNPS1,KIF3A,ZNF491,NKD1,IL6R,SLC6A17,METTL21A,CYP27C1,LAMP2,MAT2A,MBD1,CHST6,ZNF426,MINDY2,OCIAD1,SETD5,C12orf49,FOXRED2,HSPA4L,SGK1,FAM126B,SP2,CLUAP1,ZNF621,PBLD,DIP2A,ZMAT3,CBX5,PARD3,TPM4,RPL7L1,CFAP298,ZNF70,SIGLEC10,MPPE1,AP3B2" MicroRNA hsa-miR-373-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.27E-18 5.21E-14 1.75E-17 1.61E-16 64 371 "TMEM132B,SLC24A4,TXNDC16,MAP7,ZBED1,ZNF445,GPR37L1,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,RABGAP1L,MTX3,FEM1B,ELAVL2,PLEKHA1,ELAVL4,C8orf37,COQ7,FAXC,SRCAP,RNPS1,TNRC6A,FUT10,RFFL,PTGDR2,DDX19B,ARHGAP12,CHST6,MITF,DBNL,OLR1,PIK3C2A,CCSER2,ZNF426,MAPK8,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,UNC80,FNBP1,SP4,KIF1B,ADAMTS17,TMEM136,TCF7L2,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,AMOT,TOM1L2,VLDLR,TBC1D15,ZNF24,WIPF2" MicroRNA hsa-miR-1273c:mirSVR_lowEffct hsa-miR-1273c:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.84E-18 5.53E-14 1.86E-17 1.71E-16 53 266 "ZNF578,SEMA6A,PITPNM2,PHF12,VAT1L,SHROOM2,MARCH3,CACNB4,CALM1,TBPL1,PDE4DIP,PHF14,CX3CR1,HDAC4,GIT2,DCC,ABCC5,TMTC1,EIF4G2,PAN3,PSD2,GFRA2,PPARGC1A,ZNF276,AP4S1,INSYN2,LMO2,MEF2C,PAH,PCDH9,OLA1,SLC36A4,PPM1B,ACSM5,ROBO1,SALL1,ATXN7,LINC00461,FNDC3A,RAP1GAP2,SSTR1,MTCL1,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1,XPO1,NAV3,SOCS4,CPNE4" MicroRNA hsa-miR-5001-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-17 5.65E-14 1.90E-17 1.75E-16 44 188 "XKR4,MTA3,TAOK1,SLC7A14,ARSE,GYG2,IGLON5,TOGARAM2,NRG2,CPS1,PITPNM3,KIAA0408,BOC,YTHDC1,KRBA2,EDN1,RGS17,EPB41,SRARP,MSANTD4,GJB1,NXPH3,GPR45,NKD1,KCNJ9,KPNA5,LIMS1,GPR155,MOG,MDGA1,FITM2,STK32A,PNMA8A,STUM,HSPA4L,SP2,ZNF621,WWC1,GPRIN3,PCDHA6,ARL10,ERCC6L2,PARD3,AGMO" MicroRNA hsa-miR-548ap-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-17 5.84E-14 1.96E-17 1.80E-16 43 180 "XKR4,SLC24A4,TNRC6C,CDK5R1,CDC27,ZNF385A,PHF19,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,DKK3,GABRA4,NCKAP1,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,CTNNA3,OPHN1,GPR85,PPP2R2B,PTPA,NWD1,ROBO1,SALL1,TRA2B,BTBD3,SMTN,SON,AJAP1,PSD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA hsa-miR-548t-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-17 5.84E-14 1.96E-17 1.80E-16 43 180 "XKR4,SLC24A4,TNRC6C,CDK5R1,CDC27,ZNF385A,PHF19,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,DKK3,GABRA4,NCKAP1,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,CTNNA3,OPHN1,GPR85,PPP2R2B,PTPA,NWD1,ROBO1,SALL1,TRA2B,BTBD3,SMTN,SON,AJAP1,PSD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA "AGGAGTG,MIR-483:MSigDB" "AGGAGTG,MIR-483:MSigDB" MSigDB 1.06E-17 5.97E-14 2.00E-17 1.85E-16 26 63 "OGT,CAMK2G,USP6,QKI,PHACTR3,PHF20L1,RCAN2,FHL1,IGF1,CAMK2N2,MAP2,NTRK3,ODF2,MED1,SATB1,CPEB3,AMBRA1,PKNOX2,SLC6A8,SON,TMOD1,R3HDM1,SYNPO2,NSD2,XPO1,USP32P2" MicroRNA hsa-miR-371b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-17 5.98E-14 2.01E-17 1.85E-16 64 372 "TMEM132B,SLC24A4,TXNDC16,MAP7,ZBED1,ZNF445,GPR37L1,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,RABGAP1L,MTX3,FEM1B,ELAVL2,PLEKHA1,ELAVL4,C8orf37,COQ7,FAXC,SRCAP,RNPS1,TNRC6A,FUT10,RFFL,PTGDR2,DDX19B,ARHGAP12,CHST6,MITF,DBNL,OLR1,PIK3C2A,CCSER2,ZNF426,MAPK8,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,UNC80,FNBP1,SP4,KIF1B,ADAMTS17,TMEM136,TCF7L2,SLC19A3,VWCE,ZMAT3,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,AMOT,TOM1L2,VLDLR,TBC1D15,ZNF24,WIPF2" MicroRNA hsa-miR-4313:mirSVR_highEffct hsa-miR-4313:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-17 6.00E-14 2.01E-17 1.85E-16 48 222 "CARNS1,DPP10,PHF12,PPP4R4,ZFYVE28,RNF182,BRSK2,LRRFIP1,AKAP6,SLC25A27,BTF3L4,APPL1,RIPOR2,LONRF1,ZEB2,DNM1,DUSP9,ABCC5,EGR3,SRRM1,F8,EFCAB2,NBEA,FREM1,USP54,MEIS1,MT3,FXYD6,NASP,VWA2,PLP1,PRKCZ,PTPRE,ENOX1,COPZ1,RUFY2,ZSWIM8,TSPYL2,POGZ,DIP2A,TACC1,TBX15,CUX2,WDR7,TIAM1,TLR4,ZNF384,CAMK1G" MicroRNA hsa-miR-766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-17 6.35E-14 2.13E-17 1.96E-16 49 231 "RNF157,HACE1,SORCS2,PHF12,DGKD,ARHGDIA,BTRC,CBS,EVI5L,BTF3L4,CS,CSF1,PHC2,CACNG7,EN2,MTSS1L,TMEM164,GLYR1,STARD3,CECR2,ZNF496,ZBTB45,LINGO1,HMX1,NEGR1,SHISA6,MAG,NOVA2,KSR2,PKM,SMIM7,PLXNB1,PACSIN1,POLG,RAB5B,EMID1,SOX11,PEG10,DBNDD2,FAM168A,ASTN2,HIF3A,NACC2,TPD52L2,WBP2,WRN,ZNF17,NAV2,WIPF2" MicroRNA hsa-miR-8063:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-17 6.60E-14 2.21E-17 2.04E-16 45 197 "XKR4,ADCYAP1R1,ALAD,SPOP,CDC42BPA,KIAA1614,DST,JAZF1,ZMYM4,BTF3L4,TENM4,CENPL,RCAN1,EDIL3,EDN3,FEM1B,ELAVL2,DCTN4,CEP85L,AMOTL2,BRPF3,NUDT21,PRDM5,RNF165,HAS2,KIT,ARHGAP12,MAPT,PAK3,PDE1A,CCSER2,ZNF426,SETD5,CNKSR2,BDP1,PEG10,TAB2,LRRC4,DIP2A,NECAB1,TACC1,TCF7L2,SLC19A3,WNK1,SPATA13" MicroRNA hsa-miR-548aa:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-17 7.28E-14 2.44E-17 2.25E-16 43 181 "XKR4,SLC24A4,TNRC6C,CDK5R1,CDC27,ZNF385A,PHF19,PITPNC1,E2F6,EDIL3,TMTC1,AFF2,DKK3,GABRA4,NCKAP1,MIER3,ZNF678,ITPKB,KCNB1,MAT2A,SAMD5,THYN1,CTNNA3,OPHN1,GPR85,PPP2R2B,PTPA,NWD1,ROBO1,SALL1,TRA2B,BTBD3,SMTN,SON,AJAP1,PSD3,TMEM237,SLC30A3,SLC30A4,MFF,CADM2,DNALI1,GAL3ST3" MicroRNA hsa-miR-602:mirSVR_highEffct hsa-miR-602:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.31E-17 7.37E-14 2.47E-17 2.27E-16 38 142 "ARID1A,ALCAM,PCDH10,PITPNM2,ZBTB10,SLC25A14,ZMYM4,NOG,CASC2,KIAA1549L,DYRK1A,KMT5B,RASGRP2,WAC,FOXG1,FOXF2,MID1,MMP16,MSR1,NELL1,NRCAM,NUCB2,NUMA1,GPR85,GNG2,PURG,CNNM2,TMEM260,ARHGEF10L,SLC12A4,NAPB,SNAP25,KDM4C,SMOC1,RGL1,DNMBP,RGMA,KCNAB1" MicroRNA hsa-miR-1225-5p:PITA hsa-miR-1225-5p:PITA_TOP PITA 1.37E-17 7.67E-14 2.57E-17 2.36E-16 30 87 "CSMD3,SLITRK1,KIAA1324,DOC2A,CDC14B,ATP2B1,BCL2L2,CERS5,KLHL3,DCTN4,ETV1,FGF11,SEMA4D,FAM49B,MEGF10,GABRB3,IQGAP2,GRIA4,KCNA1,KCNK1,KCNMA1,L1CAM,INSYN2,ELOVL2,PTPRD,RAB5B,GTDC1,SEMA6D,ADAMTS17,TAL1" MicroRNA hsa-miR-518d-3p:mirSVR_highEffct hsa-miR-518d-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.62E-17 9.07E-14 3.03E-17 2.79E-16 43 182 "TTYH1,LRFN2,ZNF608,CASK,ARHGEF7,CFAP410,LGI1,CHGA,SMARCAL1,SOCS5,DTNA,EDN3,ANKRD13B,ACSL4,GORAB,FHL1,TACC2,NSG2,SYT17,CCDC184,ZHX1,LAMP2,MEIS2,KITLG,ZC3H12B,NDUFA5,ZNF827,EXOSC10,PPP3CB,RBBP8,ZDHHC14,ZFHX4,FBXO11,PLCB1,MCF2L,NSD1,TGFBR3,PRMT8,TSN,PLEKHH2,KCNK12,PRDM2,PARP11" MicroRNA hsa-miR-6086:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-17 9.65E-14 3.23E-17 2.97E-16 80 545 "ABCF1,NDRG3,PLEKHG5,SLC24A4,HECW2,HACE1,ZNF578,TRMT9B,AQP6,CDC14B,DOCK11,PTBP2,CBS,CBFA2T2,MYOM2,ARHGEF2,CDR1,CCPG1,JAM2,NRXN3,ZNF385A,GAPVD1,KIAA0513,TBC1D5,DNAL1,DBT,HP1BP3,MTX3,DNAH9,MRO,RASA4,MRNIP,STX2,ZNF549,ANKMY1,KATNAL1,FAM198B,ZNF585B,SCML2,FECH,KBTBD12,DISC1,CRCP,GNG4,LILRA2,KIF3A,KAT7,SCRG1,IGF1,TJAP1,IBA57,CCDC80,MXI1,NUCB1,PPP3CC,NCR3LG1,CEP97,RBBP8,ALG9,GSTCD,PTGR2,NCBP3,FNIP1,MAGI3,ATF7IP,SCN3B,FNBP1,CDK19,TAB2,ACSBG1,FAM208A,TPCN2,BHLHB9,TPM3,RFTN2,LAT2,CLDND1,ZNF17,ZNF70,EVI5" MicroRNA hsa-miR-431:PITA hsa-miR-431:PITA_TOP PITA 1.73E-17 9.69E-14 3.24E-17 2.98E-16 31 94 "ABCD2,API5,APP,ATP2B1,DPY19L3,KALRN,CANX,SOCS6,NRXN3,CLTC,SMG7,DYRK1A,HIPK3,FGF12,C1orf94,KLF12,NRCAM,HCN1,CDK14,DIRAS2,PTPRZ1,SH3TC2,SCG5,CPEB3,CPEB4,SON,CAMTA1,ZFP91,LYPD6,LAMP5,RNF103" MicroRNA hsa-miR-1207-5p:Functional MTI Functional MTI miRTarbase 1.76E-17 9.90E-14 3.31E-17 3.05E-16 55 288 "ELFN2,RNF157,PNMA8B,CPNE5,HCN2,CDK5R1,BRSK2,LONRF2,CSF1,PITPNM3,FAM131B,KIAA0513,TM9SF4,TOMM20,IP6K1,HEYL,IRAK4,WAC,TUBB4A,CELF1,TMEM151A,CPLX1,AHDC1,GFER,GJB1,FUT10,CACFD1,ZNF496,ZNF546,C5orf24,KCNK3,MAP4,PPM1L,TBC1D25,PDE3A,PKD1,PACSIN1,POLR2F,NCR3LG1,TMEM145,AMER2,SARS,MYH15,SOX11,SP2,LHPP,SSTR1,USP22,PUM2,NACC2,CBX5,TMPRSS5,DPYSL5,ITM2C,GAN" MicroRNA hsa-miR-671-3p:mirSVR_lowEffct hsa-miR-671-3p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.94E-17 1.09E-13 3.64E-17 3.35E-16 53 270 "DPF1,METAP1D,XKR4,LTBP4,VAT1L,TTLL9,KSR1,EPS15L1,SMARCAL1,ZFP28,DMTF1,DPYSL2,EDN1,EFNB3,PHF20L1,SUGP2,USPL1,EN2,FGF1,CAP2,FLT1,TACC2,HHIPL1,CRCP,GRB10,GRIA4,PTPN5,MAN1B1,C9orf129,KCNMA1,KIT,CHIC1,NTRK2,GPR88,TMEM260,TRAPPC13,ATXN7,FOXRED1,SYBU,SLC11A1,KDM4C,ZSCAN29,ADHFE1,FAM208A,WSCD1,TPCN2,ASXL3,VIPR2,FMN2,SLC26A10,LINC00632,MVB12B,UBE3B" MicroRNA hsa-miR-1227:PITA hsa-miR-1227:PITA_TOP PITA 1.97E-17 1.11E-13 3.70E-17 3.40E-16 30 88 "BSN,USP6,CDH2,QKI,ZNF521,PNKD,CREB5,ERC2,B3GAT3,HP1BP3,SNAP91,NR1D2,PHC2,FRY,GLRB,MCHR1,BACH2,NEGR1,IBA57,KCNMA1,MBNL1,ZC3H12B,POU3F2,SETD5,DOCK9,CSMD1,TRPS1,EIF4ENIF1,UBE3A,ST8SIA2" MicroRNA hsa-miR-3652:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-17 1.13E-13 3.78E-17 3.48E-16 66 397 "ABCF1,AS3MT,XKR4,ADAR,ADCY2,RNF157,ESYT2,ARHGDIA,ISPD,NEURL1,DBT,HEYL,OPTN,ABI2,TUBD1,COQ7,SEC23B,CINP,ZBED3,SPECC1,CELF1,GPR75,CNDP1,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,MKLN1,MMP17,ZNF713,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,PEX2,RAB5B,ZYG11B,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,MAGI3,ANKRD36,ERC1,SSTR2,MAPK8IP3,MPRIP,KLHL7,VWC2,GPR161,ZNF34,ZNF106,MEAF6,ZNF24,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2,GAN" MicroRNA hsa-miR-4430:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-17 1.13E-13 3.78E-17 3.48E-16 66 397 "ABCF1,AS3MT,XKR4,ADAR,ADCY2,RNF157,ESYT2,ARHGDIA,ISPD,NEURL1,DBT,HEYL,OPTN,ABI2,TUBD1,COQ7,SEC23B,CINP,ZBED3,SPECC1,CELF1,GPR75,CNDP1,LILRA2,KAT7,NKD1,IBA57,LIMS1,GPR155,MKLN1,MMP17,ZNF713,OLA1,ZNF655,PKM,GPSM2,SMOX,PIGG,PEX2,RAB5B,ZYG11B,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,MAGI3,ANKRD36,ERC1,SSTR2,MAPK8IP3,MPRIP,KLHL7,VWC2,GPR161,ZNF34,ZNF106,MEAF6,ZNF24,ZNF74,ZNF154,INTS3,TIGD6,RNF170,AP3B2,GAN" MicroRNA hsa-miR-383-5p.2:TargetScan hsa-miR-383-5p.2 TargetScan 2.07E-17 1.16E-13 3.87E-17 3.56E-16 41 167 "HECW2,PCDH19,DPP10,LRRC4C,BCL2L2,NRP2,RUNX1T1,FOXN3,PLCXD3,JAKMIP2,HIPK3,GPR61,PAN3,GPHN,FECH,NCKAP1,PPARGC1A,GRIA2,GRM5,AGFG1,NKD1,MAP2,NNAT,PAK3,PBX1,KANSL1,MAPK10,GSTCD,RORB,SATB1,NTNG1,KIF1B,CDK19,DIP2A,ANKRD28,ITGB3BP,GZF1,CBX5,FRRS1L,RGS7BP,MSRB3" MicroRNA hsa-miR-877-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.37E-17 1.33E-13 4.44E-17 4.09E-16 49 235 "DGKD,ARHGDIA,BCL2L2,MTMR3,USP2,LRRFIP1,SYNPR,TPP1,STOML1,FBXO7,TMEM184B,ARHGEF6,BTF3L4,LETMD1,SEC24C,INTS1,SEC16A,SORBS3,VPS26C,HSPA12B,TUBA1B,RACK1,AMOTL2,CAMSAP1,AFF2,CELF1,CAB39,CRCP,GLUL,CECR2,GRB10,TUBB2B,AFF1,NACA,CHAMP1,MAPK8,PROX1,CASC3,TET1,USP33,STAU1,THRA,MTMR14,ZFP91,UBC,UCHL1,ZBTB38,NELFE,C12orf4" MicroRNA hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA_TOP PITA 2.44E-17 1.37E-13 4.56E-17 4.20E-16 31 95 "ARID1A,PCDH19,MAP4K3,APP,ADGRB1,CANX,NIPBL,PCYT1B,SEC24C,EGR3,GGT7,FAM19A2,ZIC5,KCND2,MGAT3,SCAMP5,NEUROD2,NTRK3,PBX1,CAMKV,PRKCG,FBXO11,TMCC1,ZHX3,SEPT3,TCF4,PUM2,FBXL16,RIMBP2,RBFOX2,GAN" MicroRNA hsa-miR-1266:PITA hsa-miR-1266:PITA_TOP PITA 2.50E-17 1.41E-13 4.68E-17 4.31E-16 37 137 "KCNH8,CSMD2,ARID1A,SORCS1,LRFN2,CNIH2,CHRD,EIF4G3,BCL2L2,CLTC,NCOR1,CLIP3,MATR3,EDNRA,PCOLCE2,AMOTL2,IP6K2,TTBK1,PTPRT,CELF3,MBNL1,MSI1,NNAT,CAMKV,TNPO2,MED1,ZFHX4,PPP4R3A,FAM214B,ANKRD28,CAMTA1,CAMSAP2,PUM2,TIAM1,ERCC6L2,MEIS3,PARP6" MicroRNA "AGGTGCA,MIR-500:MSigDB" "AGGTGCA,MIR-500:MSigDB" MSigDB 2.83E-17 1.59E-13 5.29E-17 4.87E-16 30 89 "SORCS1,OGT,CHRD,NCOA1,DDX3Y,SLC4A7,SEC24C,MATR3,PLPPR4,DLG3,DRD1,ATL1,CELSR3,ING4,DCTN4,EPB41L1,FOXG1,NBEA,GABRB3,GPM6A,CIT,HLF,LRRTM3,KCNK10,PPP2R5E,PPP3CC,FIGN,FBXW7,CA10,ADAMTSL3" MicroRNA "ATAAGCT,MIR-21:MSigDB" "ATAAGCT,MIR-21:MSigDB" MSigDB 3.04E-17 1.71E-13 5.69E-17 5.24E-16 34 116 "ARID1A,CASKIN1,FUBP1,KRIT1,CNTFR,ACBD5,PHF14,ARHGAP24,RASGRP1,PLEKHA1,PAN3,SCML2,STAG2,PCDH17,PSRC1,HNRNPK,MATN2,MBNL1,PIK3R1,ING3,PPARA,PPP3CA,PBRM1,AP1AR,SATB1,SOX6,CPEB3,FBXO11,BTBD3,SOX2,SOX5,ITPRID2,MPRIP,RNF103" MicroRNA hsa-miR-769-5p:PITA hsa-miR-769-5p:PITA_TOP PITA 3.12E-17 1.75E-13 5.83E-17 5.37E-16 29 83 "ARID1A,SLITRK1,ZFYVE16,ELMSAN1,ABI1,ZIC4,PSD2,TBR1,WASF3,CIT,KAT7,SYNPO,KCNMA1,SCAMP5,RTL5,PABPC1L2A,LRP12,TNPO2,TMEM260,KIRREL1,AMBRA1,WDR37,SLC12A4,VAMP1,SYP,TBL1X,PSD3,TPD52,RGS7BP" MicroRNA hsa-miR-671-5p:PITA hsa-miR-671-5p:PITA_TOP PITA 3.63E-17 2.04E-13 6.78E-17 6.25E-16 36 131 "CPNE2,CSMD2,SORCS1,PPFIA3,HCN2,CFL2,DLGAP3,CREB5,IST1,CALN1,FAM57B,PHC2,EEF1A2,CELSR3,DLC1,GGT7,GPM6A,MARK1,ADAM11,SAMD5,ST8SIA5,CDIP1,PACSIN1,PPP2R5C,PTPRD,ROBO2,SLC1A2,BTBD3,SPTB,CAMTA1,TBX15,WSCD1,SATB2,FNDC5,VSNL1,FZD3" MicroRNA hsa-miR-5095:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-17 2.17E-13 7.22E-17 6.65E-16 66 402 "CLK4,ESYT2,TAOK1,ATM,ATP1B3,SLC2A11,LDHD,ZMYM4,DIS3L,PLAA,BTF3L4,LETMD1,RNF14,SOCS5,KBTBD11,SLC12A6,ABI2,EIF4G2,IRAK4,MRNIP,TUBD1,SLC43A2,TUBA1B,CEP78,FDFT1,GTF2IRD2,ZNF44,GABRB1,TRAF3IP2,TXNL4A,RNPS1,KIF3A,ZNF491,NKD1,IL6R,SLC6A17,METTL21A,CYP27C1,LAMP2,MAT2A,MBD1,CHST6,ZNF426,MINDY2,OCIAD1,SETD5,C12orf49,FOXRED2,HSPA4L,SGK1,FAM126B,SP2,CLUAP1,ZNF621,PBLD,DIP2A,ZMAT3,CBX5,PARD3,TPM4,RPL7L1,CFAP298,ZNF70,SIGLEC10,MPPE1,AP3B2" MicroRNA hsa-miR-29a-3p:Functional MTI Functional MTI miRTarbase 3.94E-17 2.21E-13 7.35E-17 6.77E-16 52 265 "CDC7,BCL7A,FMNL3,CDC42,QKI,ELMSAN1,FEM1B,RASGRP1,SH3GLB1,GOLGA7,ELN,SYNCRIP,FOXO3,DOT1L,GLUL,HMGCR,IGF1,GAREM2,LAMA2,LIMS1,MYCN,HNRNPM,NASP,NFIA,ENPP2,GPR85,PIK3R1,KCTD15,TRIM68,RET,GTDC1,RNASEL,ROBO1,GLDN,S100B,SARS,SLC30A10,SGK1,CPEB3,SEC31A,TET1,CPEB4,MAPKBP1,SP2,HECW1,DICER1,ZFP91,TUBB2A,CCDC14,TMEM237,ADAMTS9,NAV3" MicroRNA hsa-miR-9500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-17 2.25E-13 7.47E-17 6.88E-16 45 203 "ELFN2,OGT,ARHGDIA,ARRB2,TTLL9,BCL7A,LDHD,HAP1,USP2,TM9SF4,ABI2,HSPA12B,GTF2IRD2,CAMKK2,GFER,CRCP,RAPGEF1,GSN,NXPH3,SHISA6,SOWAHA,C5orf24,NKD1,PABPC1L2A,NFIX,NPTX2,CLDN11,KCTD15,NLE1,PACSIN1,NCR3LG1,RAB3A,RAB5B,PRRT2,SLC25A36,MYH14,PEX26,NACC2,TPD52L2,TPM3,WBP2,TUBB2A,MEAF6,INTS3,URM1" MicroRNA hsa-miR-544a:TargetScan hsa-miR-544a TargetScan 4.00E-17 2.25E-13 7.47E-17 6.88E-16 42 178 "KCNH8,FMNL2,AQP4,PTBP2,CAMK2B,RUNX1T1,KRIT1,CDC27,CDH8,DLGAP3,LETMD1,PITPNM3,GAPVD1,JAKMIP2,G3BP2,E2F5,IRAK4,FLT1,GAB1,RAPGEF6,GFRA1,GPT2,LNX1,KIF2A,BLOC1S2,CTNNA3,NF1,NPTX1,NTRK2,PLP1,ARID4A,ATXN2,ATXN7,SCN2A,CCDC88A,CPEB4,ANKRD12,FAM208A,RPGRIP1L,HHIP,DOK6,HNRNPA3" MicroRNA hsa-miR-4326:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.72E-17 2.65E-13 8.81E-17 8.12E-16 27 72 "C3orf14,C1QTNF3,ARHGDIA,ARSE,CCNT1,LONRF2,CLTC,TMEM184B,RTTN,IGDCC3,SMG7,G3BP2,FEM1B,ERBB2,FER,SIGLEC8,NFYA,OGDH,SLC25A36,HSD11B1L,SLC2A5,VPS13A,MLST8,ZNF34,HEY2,TNS1,RBFOX2" MicroRNA hsa-miR-409-5p:TargetScan hsa-miR-409-5p TargetScan 4.79E-17 2.69E-13 8.93E-17 8.23E-16 31 97 "ABAT,ADCY6,GALNT13,ANK3,DPY19L3,DCAF5,AIF1L,DNAJC6,CELSR3,EIF1,RASL12,MMADHC,PPARGC1A,PCLO,KLF12,LRRTM3,KCNA1,KCNB1,KCND3,PPM1L,PEG10,ARHGAP26,KIF1B,CAMTA1,C5orf64,LRTM2,KLC2,LRP8,PIANP,NETO2,CBLN2" MicroRNA hsa-miR-619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.10E-17 2.87E-13 9.51E-17 8.76E-16 68 425 "ZNF578,TAOK1,KIF6,MTMR9,BCL2L2,LDHD,AP1M1,FOXK1,PLAA,COL9A2,CRY2,RGS6,CSNK1E,PPP1R16B,UBXN2A,DNAL1,RABGAP1L,SLC12A6,ABI2,IRAK4,MRPL37,VPS26C,TLR7,CEP78,GTF2IRD2,FOXO3,TRAF3IP2,MTHFD2,KIAA1841,TXNL4A,CRCP,POLL,KIF3A,BVES,MFSD2A,HMGB1,ZDHHC15,NEGR1,ATCAY,IL6R,KCND3,CYP27C1,GPR155,MBD1,CHST6,MINDY2,OCIAD1,C12orf49,PGBD4,FOXRED2,HSPA4L,PEX26,FAM126B,SP2,EMC1,AJAP1,ACSBG1,WWC1,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,ZNF70,ZBTB38,MPPE1" MicroRNA hsa-miR-4755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.35E-17 3.00E-13 9.97E-17 9.18E-16 55 295 "APAF1,ARHGDIA,ATP1A2,NOL4,CBS,NUMBL,ZFYVE9,AKAP6,CSNK1E,UBXN2A,GREB1,MYADM,DBT,RABGAP1L,EXOG,POLR1B,TRMO,CRCP,GRK4,KIF3A,CELF3,IRAK3,DDX19B,TJAP1,CYP27C1,MAN2A2,MYO6,CAMKV,PIK3R1,TNPO2,PPARA,MINDY2,ZNF793,SGSM1,RPS6KA2,PTGR2,PEAR1,SH3BP2,R3HDM2,PEX26,EPN2,TRIM67,FAM126B,KIF21B,KIF1B,SSTR2,SEPT8,ALG1,SIN3B,RBFOX2,UBTF,ZNF28,ZNF70,NETO2,GAN" MicroRNA hsa-miR-423-5p:PITA hsa-miR-423-5p:PITA_TOP PITA 5.45E-17 3.06E-13 1.02E-16 9.36E-16 34 118 "ASIC1,ACHE,ZNF608,CADM3,ADGRB1,HAP1,CDC42,ZNF385A,RIMS4,PUM1,LYPD1,SRGAP3,G3BP2,EFNA3,EGR3,ANKRD13B,AGAP2,AGAP3,AHDC1,RNF165,BACH2,NFIX,NPTX1,NTRK3,PDE1B,EPB41L4B,PKIA,TMEM260,SMARCC2,MYT1L,ERC1,PLCB1,SYP,SMG6" MicroRNA hsa-miR-431-5p:TargetScan hsa-miR-431-5p TargetScan 5.51E-17 3.09E-13 1.03E-16 9.45E-16 33 111 "PTCHD1,ATP2B1,DPY19L3,DST,AIFM1,NRXN3,COG1,CLTC,BTF3L4,NRG2,AKAP12,HIPK3,EPB41L1,NSG2,BRPF3,RNFT2,C1orf94,KLF12,MEIS1,HCN1,CDK14,CCSER2,DIRAS2,MDGA2,RAB5B,ALG9,ARHGEF40,CCDC88A,HHIP,PPIL6,LYPD6,LAMP5,NETO1" MicroRNA hsa-miR-4667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-17 3.27E-13 1.08E-16 9.98E-16 50 249 "SLC12A5,ARRB1,ARSE,GPR146,BTK,CACNB2,CDH8,SLC22A6,STOML1,TOGARAM2,TENM4,PHF19,TMEM170A,CTIF,SMG7,EMX2,SRARP,ANKMY1,PDLIM5,GABRG2,RAB30,KIAA1958,MAP4K5,GPR45,KIFC3,CYP27C1,LSAMP,MDFI,MYO5A,NEXMIF,GTDC1,CYB561D1,RXRA,STX1B,WDR37,BTBD3,SHANK2,SMARCE1,MAPKBP1,ZSCAN29,NSFL1C,SZT2,NSD1,CRTC1,KCNK12,ZBTB16,AMZ1,ZNF225,URM1,JPH3" MicroRNA hsa-miR-3124-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.95E-17 3.34E-13 1.11E-16 1.02E-15 45 205 "SLC25A25,FMNL2,KCTD16,SPOP,CDC42BPA,GAS7,PRX,ATP1A1,RUNX1T1,ZBED1,LRRFIP1,TOMM20,EPHB1,SLC43A2,CEP85L,CDHR1,MRVI1,CEP78,UFM1,PPARGC1A,GRID1,PTGDR2,HMGCR,LSAMP,MBNL1,MYO5A,GLIPR1L2,ZNF426,PIGG,RAVER2,SPIN3,TCP11L1,ATXN7,SCN2B,SP4,SMOC1,TMEM136,SLC19A3,AHCYL2,ZFP91,C5orf64,RUNDC3B,RICTOR,ZNF138,FRMD6" MicroRNA hsa-miR-6720-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-17 3.61E-13 1.20E-16 1.10E-15 77 524 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,ARSE,GPR146,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,MTX3,EBI3,IRAK4,EPB41,ANKFY1,TRMO,ZNF234,FAXC,CRCP,GPR75,GPT2,RAPGEF1,PARD3B,NR3C1,DDX19B,AGBL5,DOCK7,SLC6A17,CHST6,CCDC80,ZC3H12B,NODAL,SLC11A2,MTRF1L,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ZNF331,SALL1,IL17RB,SGK1,MAGI3,SEPHS1,RADIL,FAM126B,EMC1,MCF2L2,SSTR2,C3orf70,ZFP91,PPIL6,SSBP2,TMEFF2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,WNK1,SLC30A4,XKR7,TRIM16L,PIANP,GAN" MicroRNA hsa-miR-371a-5p:Functional MTI Functional MTI miRTarbase 6.48E-17 3.64E-13 1.21E-16 1.11E-15 60 345 "TMEM132B,SLC24A4,TXNDC16,CPNE5,MAP7,ZBED1,ZNF445,STOML1,ARHGEF6,SEC14L5,PYGO1,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,RABGAP1L,FEM1B,ELAVL2,PLEKHA1,ELAVL4,C8orf37,COQ7,FAXC,SRCAP,TNRC6A,FUT10,HAS2,DDX19B,HSP90AA1,ZNF678,CHST6,MITF,DBNL,MYCN,OLR1,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,SOX2,SP4,KIF1B,ADAMTS17,TMEM136,SLC19A3,VWCE,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,SF1,ZNF24,WIPF2" MicroRNA hsa-miR-645:PITA hsa-miR-645:PITA_TOP PITA 6.55E-17 3.68E-13 1.22E-16 1.12E-15 29 85 "DPY19L3,SYNGR3,QKI,ZNF521,CREB5,SEC24C,PUM1,DYRK1A,PHYHIPL,NCKAP1,GRB10,FRMD5,MIER3,LRRTM3,KCNK2,GPR155,MEF2C,MITF,PPP3CB,PPM1E,SEPHS1,SLC8A1,SOX11,ZSWIM8,HECW1,TCF12,ZFP91,XPO1,WNK1" MicroRNA hsa-miR-938:PITA hsa-miR-938:PITA_TOP PITA 6.66E-17 3.74E-13 1.24E-16 1.14E-15 31 98 "KLHL13,APAF1,SHTN1,USP6,DGKI,NUMBL,RCHY1,PNKD,CREB5,TOMM20,SACS,ELAVL3,AFF2,NPTN,AHCYL1,GPM6A,RFFL,FRMD3,KIF2A,NUMA1,RIPOR1,TMEM100,NTNG1,SOX11,TRIM2,TIAM1,FNDC5,FAM155A,PRDM8,PHTF2,VANGL2" MicroRNA hsa-miR-1343-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.73E-17 3.78E-13 1.25E-16 1.15E-15 47 223 "AS3MT,PRX,ARHGDIA,SLC4A4,CBS,CCNT1,DIS3L,BTF3L4,CSNK1E,ZBTB24,RABGAP1L,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,UFM1,NCKAP1,KDM2B,CNDP1,LILRA2,SCRG1,KCNK1,KPNA5,MOG,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,AMBRA1,BDP1,ALG1,AGTPBP1,ARL10,CBX5,PARD3,WBP2,SSBP2,KLC2,ZBTB16,RNF170" MicroRNA hsa-miR-6783-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.73E-17 3.78E-13 1.25E-16 1.15E-15 47 223 "AS3MT,PRX,ARHGDIA,SLC4A4,CBS,CCNT1,DIS3L,BTF3L4,CSNK1E,ZBTB24,RABGAP1L,FEM1B,RGS17,TUBD1,SLC43A2,IGSF6,AMOTL2,UFM1,NCKAP1,KDM2B,CNDP1,LILRA2,SCRG1,KCNK1,KPNA5,MOG,SAMD5,PIK3R1,MTRF1L,FITM2,APTX,ZSCAN2,GTDC1,STX1B,FAM192A,AMBRA1,BDP1,ALG1,AGTPBP1,ARL10,CBX5,PARD3,WBP2,SSBP2,KLC2,ZBTB16,RNF170" MicroRNA hsa-miR-7111-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.75E-17 3.79E-13 1.25E-16 1.16E-15 51 259 "RNF157,HACE1,SORCS2,TAOK1,ANK1,PPFIA3,PRX,CAMK2A,METTL6,DLGAP3,TMEM184B,CRMP1,PLEKHM1,PHC2,EFNA3,EIF4G1,ANKRD13B,WAC,AFF2,CELF1,PRRC2B,KCNH2,CHST6,NDUFA5,NEUROD2,NOVA2,NRGN,CCSER2,PKM,SPATA6,PTPA,DIRAS2,BDNF-AS,PRRT2,SETD5,MYH14,EMID1,SMTN,PKNOX2,FNBP1,ERC1,RAP1GAP2,NFASC,USP22,HHIP,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-1292:mirSVR_highEffct hsa-miR-1292:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.82E-17 3.83E-13 1.27E-16 1.17E-15 35 126 "XKR4,STX16,DST,CDH18,CHN2,NRXN3,CNTN1,PDE4DIP,ST18,EDRF1,PITPNC1,ZNF582-AS1,ADGRV1,GAD2,TUBGCP4,KCNMA1,MTTP,LYRM9,NNAT,PCSK2,HYDIN,TMEM104,ERI2,SETD5,ITSN1,CPEB3,ZNF365,SLC11A1,EFHD1,SNRPN,KIF1B,MPRIP,TK2,ZNF23,CAB39L" MicroRNA hsa-miR-219a-2-3p:TargetScan hsa-miR-219a-2-3p TargetScan 7.03E-17 3.95E-13 1.31E-16 1.20E-15 37 141 "ABAT,ERMN,HACE1,PDE8B,DST,LDB2,DGKI,LETMD1,ARHGEF10,ERBB4,ATP8A1,ANKFY1,PSD2,GAB1,RAPGEF6,IQGAP2,GLYR1,MIER3,HNRNPK,IGF1,SCRT2,MEF2C,MXI1,MYO5A,NOVA2,GPR173,MAPK8,KHDRBS2,KLHL11,SATB1,FAM208A,RPGRIP1L,DOK6,KCNK12,PMEPA1,CERS6,GAN" MicroRNA hsa-miR-134-5p:TargetScan hsa-miR-134-5p TargetScan 9.05E-17 5.08E-13 1.68E-16 1.55E-15 37 142 "ELFN2,EPB41L5,CDK13,NIPA1,CDR1,CPS1,RIMS2,JAKMIP2,CDON,DRP2,ABI2,PLXNC1,CEP85L,MRVI1,GABRB1,MTHFD2,GBX2,GNAO1,GRIK2,GRIK3,KAT7,HAS2,HPSE2,HNMT,IDH3A,MAT2A,MBNL1,PAK3,CEP41,RIMKLA,IQSEC2,FAM168A,ADAMTS17,CNTN2,PSD3,KCNK12,PIANP" MicroRNA hsa-miR-617:PITA hsa-miR-617:PITA_TOP PITA 9.23E-17 5.19E-13 1.71E-16 1.58E-15 31 99 "SYN3,SOCS6,SOCS5,PLCXD3,FRMPD4,G3BP2,NCALD,SORBS1,CHL1,ERAP1,TCERG1,RAB30,ARHGAP12,ZC3H12B,PIK3R1,RETREG2,EPB41L4B,TNPO2,PDZD2,SOX1,SOX11,CDK19,STXBP1,UNC5D,ZNF106,FBXL16,TIAM1,ZFP91,SLC38A1,MVB12B,PAK5" MicroRNA hsa-miR-604:mirSVR_highEffct hsa-miR-604:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.23E-17 5.19E-13 1.71E-16 1.58E-15 31 99 "ABHD6,ALDH4A1,ATP2A2,ARHGEF7,ENTPD6,NIPBL,SMARCAL1,ZNF521,PNKD,CDC42BPB,CFAP61,HDAC4,PLEKHA1,TAOK3,SPECC1,SULT1C4,GRB10,GRIK5,LINC01551,AP4S1,NOVA1,PAK3,ANKRD16,MED1,ATAT1,SEPT3,TPM1,NTSR2,LGI4,TMEM198,SEMA3B" MicroRNA hsa-miR-3179:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.45E-17 5.31E-13 1.75E-16 1.61E-15 42 182 "TRMT9B,OGT,APAF1,HCN2,CA8,ZNF385A,FRMPD4,IP6K1,SPATA2,DUSP9,MRO,POLL,RAPGEF1,ZNF496,NXPH3,TNFAIP8L3,ZFYVE27,MAT2A,SAMD14,PABPC1L2A,CLDN11,PKM,KCTD15,FXYD1,EPB41L4B,PTPA,SH3TC2,SETD5,SH3BP2,SP2,FAM168A,USP22,ZNF34,NACC2,TMPRSS5,UBTF,MEAF6,INTS3,CIAPIN1,URM1,NAV2,GAN" MicroRNA hsa-miR-142-5p:Functional MTI Functional MTI miRTarbase 9.74E-17 5.47E-13 1.81E-16 1.66E-15 47 225 "CC2D2A,SEMA7A,CAPRIN2,CALM1,SLC24A2,RIMS4,UBXN2A,FAM107B,CERCAM,RCAN2,DLC1,FOXO3,C15orf41,LUZP2,FUT10,KIF3A,BACH2,MAT2A,MKLN1,NFE2L2,PDE4D,PFKP,ZFYVE21,PDZRN4,PRKCB,SLC22A23,PEX2,CEP97,FIGN,ALG9,ROBO1,ACER3,ATXN1,FAM126B,SON,ZBTB43,SMOC1,ANKRD28,ZEB1,SIRT1,TNS1,RGMB,SMUG1,UBE2H,ZNF711,SLC38A1,STOX2" MicroRNA "ACATATC,MIR-190:MSigDB" "ACATATC,MIR-190:MSigDB" MSigDB 1.09E-16 6.10E-13 2.01E-16 1.85E-15 24 57 "SLITRK1,TBC1D14,SYNJ1,CLOCK,DMD,PHF20L1,GPHN,MEX3B,TNRC6A,HAS2,BACH2,MYO5A,NEUROD1,PAX6,PCDH9,PTHLH,NLGN1,NFASC,ANO4,TCF4,TRPS1,ZIC3,CELF4,NAV3" MicroRNA hsa-miR-421:Functional MTI Functional MTI miRTarbase 1.19E-16 6.66E-13 2.20E-16 2.02E-15 48 235 "TNRC6C,ATM,BTRC,ARHGAP22,NIPBL,RAB26,NSL1,RIMS4,E2F6,EIF4G2,DNAJC27,AMZ2,TUBA1B,MTHFD2,PPARGC1A,MSL3,KCNMB4,NR3C1,ATXN2L,NEGR1,HSP90AA1,IGF1,GAREM2,ZNF678,KCNN3,LIMS1,PAXBP1,MYBPC1,NPTX1,PDPK1,POLG,MAPK8,RGR,FBXO11,TET1,SLIT1,NCDN,SYT4,TAF9,TCF7L2,FBXL16,RGMB,ZMYND8,TUBB2A,ZXDA,PARP11,ZNF30,SENP7" MicroRNA hsa-miR-3646:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-16 6.74E-13 2.22E-16 2.05E-15 44 200 "APP,STX16,MAP7,TOGARAM2,OSBPL3,SPATA2,CEP170,G3BP2,E2F6,SEMA3D,SH3GLB1,NPTN,CELF1,GABRB1,TUBGCP4,COPS8,TNRC6A,NUDT21,RAPGEF1,CIT,FICD,MYBPC1,CLDN11,PDE4D,PSAT1,SH3TC2,ERI2,RFX3,ATAT1,TRA2B,HSPA4L,SGK1,BDP1,ITPRID2,DDHD2,ZMAT3,ZNF34,SLC44A1,UGT8,MFF,CSDE1,ZDHHC20,FXR1,NETO2" MicroRNA hsa-miR-483-5p:mirSVR_highEffct hsa-miR-483-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.23E-16 6.92E-13 2.28E-16 2.10E-15 41 175 "SLC12A5,ALCAM,MAGEE2,GPAM,ARHGDIA,DACT3,MYOM2,CLCN3,SUMF2,DOCK4,TCAF1,DAPK1,KIF19,ARNT2,DLX1,SLC25A18,SLC43A2,MRPL37,RRAGB,ADGRV1,FDFT1,TMEM107,LRRC37A6P,GPT2,DIDO1,DNHD1,A2ML1,RC3H2,MAPK3,NCBP3,ASRGL1,ANKRD6,ATF7IP,RCOR3,IQSEC2,IQCE,SATB2,PCDHB9,ATP13A2,TIAM1,RUSC1" MicroRNA "ACTGCAG,MIR-17-3P:MSigDB" "ACTGCAG,MIR-17-3P:MSigDB" MSigDB 1.27E-16 7.15E-13 2.36E-16 2.17E-15 31 100 "SLITRK1,SORCS2,OGT,SHTN1,CAMK2D,ARMC8,TM9SF4,EIF4G1,OLFM1,NR3C1,KAT7,KCNMA1,MAP4,MEIS1,RTL5,CNOT4,NRDC,NTRK2,KANSL1,NKAIN1,GTDC1,ZFHX4,ITSN1,USP33,SOX11,ZNF423,ZIC3,FSTL5,CSDE1,PARP6,SNX27" MicroRNA hsa-miR-4252:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-16 8.22E-13 2.71E-16 2.49E-15 70 455 "CLK4,ELFN2,SLC24A4,HECW2,HACE1,TBC1D14,TXNDC16,TAOK1,PHF12,AMER3,AQP6,CDC14B,ZNF555,SLC16A4,CBFA2T2,NRXN3,COL9A2,UBXN2A,TMEM170A,DNAL1,MTX3,MRNIP,EPB41,ATP13A4,CELF1,ZNF234,FAXC,GPR75,TNRC6A,KIF3A,MFSD2A,DDX19B,HMGB1,ZNF491,ZNF546,DOCK7,IL6ST,IBA57,CHST6,ZC3H12B,MINDY2,STK32A,TMEM145,ZNF844,RAB5B,TRIM68,ALG9,FBXW7,ATAT1,MAGI3,FNBP1,EMC1,LHPP,SSTR2,C3orf70,USP22,ARL10,CBX5,RUNDC3B,PPIL6,SSBP2,TMEFF2,ZNF610,RPL7L1,LAT2,ZNF70,PLPP4,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-1224-5p:TargetScan hsa-miR-1224-5p TargetScan 1.57E-16 8.82E-13 2.90E-16 2.67E-15 38 152 "C3orf14,ELFN2,ADORA1,PTCHD1,RUNX1T1,PRC1,FMNL3,RIMS4,PLCXD3,GRIN3A,DYRK1A,FGF1,FGFR1,ANKFY1,NCKAP1,MMADHC,GPD1,AGFG1,KCNK3,IPO5,CHIC1,MMP16,CCDC80,BLOC1S2,NOVA1,GPR137C,PKD1,MAPK4,MAPK10,PRRT2,GTDC1,FIGN,RPE,SATB1,ITSN1,KIF21B,CBX5,PRRT4" MicroRNA hsa-miR-4763-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-16 8.99E-13 2.96E-16 2.73E-15 53 283 "ELFN2,RNF157,PNMA8B,CPNE5,HCN2,BRSK2,LONRF2,PITPNM3,FAM131B,KIAA0513,TM9SF4,TOMM20,IP6K1,HEYL,IRAK4,WAC,TUBB4A,CELF1,TMEM151A,CPLX1,AHDC1,GFER,GJB1,FUT10,CACFD1,ZNF496,ZNF546,C5orf24,KCNK3,MAP4,PPM1L,TBC1D25,PDE3A,PKD1,PACSIN1,POLR2F,NCR3LG1,TMEM145,AMER2,SARS,MYH15,SOX11,SP2,LHPP,SSTR1,USP22,PUM2,NACC2,CBX5,TMPRSS5,DPYSL5,ITM2C,GAN" MicroRNA hsa-miR-3181:mirSVR_lowEffct hsa-miR-3181:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.63E-16 9.16E-13 3.01E-16 2.78E-15 56 312 "ADORA2A,ADRA1D,SPOP,PITPNM2,AMPD2,SEMA7A,ASCL1,CCAR2,ATP2A2,RGS11,RGS9,PPT2,ZNF521,SNCAIP,ELMSAN1,RABGAP1L,RASGRP2,TUBB3,GLI2,RAB30,GLS,WIF1,IDH3A,KCNK2,L1CAM,CAMK2N2,NOVA2,PCBP3,SETD4,SNTG1,NLGN3,NLE1,PURG,POLR2F,NKAIN4,FAM66C,UBR7,STK32B,CLSTN1,RCOR3,SP2,KDM4C,UNC5B,MTCL1,TPCN2,WDR7,AKNA,FBXL16,TLL2,FLRT2,PLPPR2,P2RY12,SF1,SLC26A10,MEIS3,FBXO36" MicroRNA hsa-miR-5089-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-16 9.21E-13 3.03E-16 2.79E-15 62 372 "ZNF578,TAOK1,KIF6,MTMR9,BCL2L2,LDHD,FOXK1,PLAA,NRG2,CLOCK,CRY2,CSNK1E,PPP1R16B,UBXN2A,RABGAP1L,SLC12A6,ABI2,IRAK4,EPB41L1,TLR7,GTF2IRD2,FOXO3,TRAF3IP2,KIAA1841,TXNL4A,CRCP,GRIK2,KIF3A,MFSD2A,HMGB1,ZDHHC15,ATCAY,METTL21A,KCND3,CYP27C1,STMN1,GPR155,MBD1,CHST6,MINDY2,OCIAD1,FOXRED2,GALNT10,HSPA4L,PEX26,LRRC55,FAM126B,SP2,EMC1,STAU1,ALG1,WWC1,CLASP1,NSD1,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,MPPE1" MicroRNA hsa-miR-99a*:mirSVR_highEffct hsa-miR-99a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.78E-16 1.00E-12 3.29E-16 3.03E-15 33 115 "TTLL9,ARHGEF7,RUNX1T1,AKAP7,CREM,FEZ2,HS3ST2,FCF1,WAC,MEX3B,EFCAB2,OGA,ZNF276,TCERG1,NCKAP1L,KCNQ3,MYBPC1,PKN2,TMEM255A,RBBP6,ZYG11B,CNTNAP3,ATXN7,CNKSR2,SLC1A7,SORCS3,ZC3H4,TCF7L2,TIAM1,TMPO,DCBLD1,WIPF1,PRTFDC1" MicroRNA hsa-miR-4743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-16 1.02E-12 3.34E-16 3.08E-15 32 108 "ARID1A,MIER1,SFMBT2,RASL11B,NIPA1,FOXN3,LRIG1,PLCXD3,TMEM130,DPP6,DNAJB6,RASGRP1,EIF4G2,MRNIP,TAOK3,FOXG1,SYNCRIP,GABRA1,FAXC,GRIK4,KLF12,KSR2,GLIPR1L2,PDE3A,PKIA,TTLL7,SOX1,BDP1,EMC1,SZT2,WNK1,SLC38A1" MicroRNA hsa-miR-7847-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-16 1.06E-12 3.49E-16 3.21E-15 56 313 "ABCF1,ADCY5,PNMA8B,HACE1,PTBP2,CBS,BTF3L4,CSF1,GAPVD1,KIAA0513,SIRPA,DNAL1,HP1BP3,ZC3H11A,SGSM2,MRO,DMTN,FGFR1,CAMKK2,NEURL4,CSDC2,LILRA2,HMX1,SHISA6,IGF1,MAP2,MAT2A,SESN3,MXI1,KSR2,GPR137C,TMOD2,PKM,PLEC,PLXNB1,PACSIN1,NCR3LG1,RAP1GDS1,PGBD4,KIAA0895L,NCBP3,MYO18A,KIF13A,SOX11,PEG10,DBNDD2,CDK19,AGTPBP1,ATMIN,WBP2,TRPC3,LAT2,WRN,ZNF17,EVI5,PARP11" MicroRNA hsa-miR-6769b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-16 1.07E-12 3.50E-16 3.22E-15 45 211 "SERPINA3,ACTN2,XKR4,ADCY6,SORCS2,ARHGDIA,ATP2B1,LDLRAD4,CDH8,GPR37L1,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,SMG7,TMCC2,ABI2,ZNF391,ANKMY1,AMOTL2,GRID1,PTGDR2,SHISA6,KCNN3,PAK3,GDAP1L1,POU6F1,KANSL1,C12orf49,ASIC4,GALNT10,SMARCE1,CLUAP1,ERC1,ACSBG1,TMEM178B,TMEM151B,CRTC1,TGFBR3,TMPRSS5,DPYSL5,FRMD6" MicroRNA hsa-miR-6512-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-16 1.07E-12 3.51E-16 3.24E-15 76 523 "XKR4,ADD1,SLC24A4,HACE1,KIAA1324,TXNDC16,AQP6,CDC14B,ARSE,GPR146,ZNF555,CBS,SLC16A4,NRXN3,SUSD5,UBXN2A,CENPL,TMEM170A,DNAL1,MTX3,EBI3,IRAK4,ANKFY1,TRMO,ZNF234,FAXC,CRCP,GPR75,GPT2,RAPGEF1,PARD3B,NR3C1,DDX19B,AGBL5,DOCK7,SLC6A17,CHST6,CCDC80,ZC3H12B,NODAL,SLC11A2,MTRF1L,TATDN3,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ZNF331,SALL1,IL17RB,SGK1,MAGI3,SEPHS1,RADIL,FAM126B,EMC1,MCF2L2,SSTR2,C3orf70,ZFP91,PPIL6,SSBP2,TMEFF2,ZNF610,UBC,RPL7L1,USP1,MGAT5B,TBC1D15,WNK1,SLC30A4,XKR7,TRIM16L,PIANP,GAN" MicroRNA hsa-miR-3183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-16 1.29E-12 4.22E-16 3.89E-15 45 212 "SERPINA3,ACTN2,XKR4,ADCY6,SORCS2,ARHGDIA,ATP2B1,LDLRAD4,CDH8,GPR37L1,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,SMG7,TMCC2,ABI2,ZNF391,ANKMY1,AMOTL2,GRID1,PTGDR2,SHISA6,KCNN3,PAK3,GDAP1L1,POU6F1,KANSL1,C12orf49,ASIC4,GALNT10,SMARCE1,CLUAP1,ERC1,ACSBG1,TMEM178B,TMEM151B,CRTC1,TGFBR3,TMPRSS5,DPYSL5,FRMD6" MicroRNA hsa-miR-4723-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-16 1.29E-12 4.22E-16 3.89E-15 45 212 "SERPINA3,ACTN2,XKR4,ADCY6,SORCS2,ARHGDIA,ATP2B1,LDLRAD4,CDH8,GPR37L1,IGLON5,PITPNM3,UBXN2A,PLCXD3,CYBB,KIAA0408,TMEM170A,SMG7,TMCC2,ABI2,ZNF391,ANKMY1,AMOTL2,GRID1,PTGDR2,SHISA6,KCNN3,PAK3,GDAP1L1,POU6F1,KANSL1,C12orf49,ASIC4,GALNT10,SMARCE1,CLUAP1,ERC1,ACSBG1,TMEM178B,TMEM151B,CRTC1,TGFBR3,TMPRSS5,DPYSL5,FRMD6" MicroRNA hsa-miR-3178:mirSVR_lowEffct hsa-miR-3178:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.34E-16 1.31E-12 4.31E-16 3.97E-15 41 178 "AP1B1,AMH,LRFN1,AQP6,ARHGDIG,ASGR1,MARK4,EVI5L,COX4I1,CREM,SPATA2,DMPK,EEF1A2,CACNG7,EPHB1,ANKRD13B,ZNF391,BAIAP2,POLK,AGAP3,ZNF274,TTBK1,MUM1,TLX1,HES5,INSM1,MSI1,NNAT,FXYD1,MAPK4,RIPOR1,NKAIN1,RAB3IL1,MAPK12,RASA3,DHX30,MCF2L2,CAMTA2,IQCE,FBXL16,NEIL2" MicroRNA hsa-miR-518a-3p:mirSVR_highEffct hsa-miR-518a-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.42E-16 1.36E-12 4.46E-16 4.11E-15 43 195 "TTYH1,LRFN2,ZNF608,CASK,ARHGEF7,CFAP410,LGI1,SMARCAL1,SOCS5,DTNA,EDN3,ANKRD13B,ACSL4,FGFR1,FHL1,TACC2,NSG2,SYT17,CCDC184,ZHX1,LAMP2,KITLG,ZC3H12B,NDUFA5,ZNF827,EXOSC10,PPP3CB,RBBP8,ZDHHC14,ZFHX4,FBXO11,FNDC3A,PLCB1,MCF2L,TBCEL,NSD1,TGFBR3,GZF1,TSN,PLEKHH2,KCNK12,PRDM2,PARP11" MicroRNA hsa-miR-1305:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-16 1.36E-12 4.46E-16 4.11E-15 43 195 "RNF150,TNRC6C,CALM1,RIMS4,TMTC1,FSD1L,SLC37A3,MSANTD4,NCKAP1,FAXC,GFRA1,KCNMB4,IGF1,ZNF678,KCNB1,KPNA5,NPTX1,SH3KBP1,PPARA,SH3TC2,BSDC1,GTDC1,LRRTM4,FNDC3A,SLC8A1,TET1,IGSF9B,CLUAP1,EPB41L3,FAM208A,TCF7L2,ARL10,ASXL3,LRRC8A,TUBB2A,UBE2H,VLDLR,ZNF24,KCNT2,ZNF225,SLC30A4,ZXDA,PRDM10" MicroRNA hsa-miR-4719:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-16 1.41E-12 4.62E-16 4.26E-15 38 154 "BACH1,KIAA1549L,LIN54,DCC,CPEB2,PLXNC1,SRARP,PNMA2,NEU3,KIAA1958,GRM5,KAT7,USP51,MSI1,MYO6,NPTX1,OLR1,PDGFRA,CCSER2,PDZRN4,MAGEL2,FAT3,OCIAD1,HUNK,NCBP3,FNIP1,PPP4R3A,SLC12A2,PEG10,ZBTB43,NECAB1,DNAJC9,SYT4,TAL1,LRRC8A,TUBB2A,HNRNPA3,SSPN" MicroRNA hsa-miR-548e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-16 1.47E-12 4.82E-16 4.44E-15 44 204 "ADORA3,ARMC12,NCOA1,KSR1,RUNX1T1,TBPL1,OSBPL3,PUM1,PHF19,MYEF2,DPYSL2,DNAJB6,EIF1,KATNAL1,IQCG,NCKAP1,IQGAP2,SESN1,TNRC6A,GPM6A,PCLO,CREG2,MAT2A,ZNF680,SESN3,NFYA,GPR85,PSAT1,SDK2,PACSIN1,TTLL7,CSRNP3,CPEB3,SLC6A1,SON,SOX3,ZHX3,FAM168A,SYPL1,AGTPBP1,RBFOX2,TUBB2A,AMOT,ZXDA" MicroRNA hsa-miR-1238:mirSVR_highEffct hsa-miR-1238:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.76E-16 1.55E-12 5.08E-16 4.68E-15 45 213 "SLITRK1,API5,ARNTL,ATM,ADAM23,IL33,MAGI1,JAM2,LHX2,AKAP7,RGS6,CSNK1G3,GAPVD1,BRINP1,GIT2,JAKMIP2,EXOG,ELAVL4,EIF1,EPHB1,ZIC4,SEMA6C,SMC2,NSG1,DISC1,MSTN,GNAS,CIT,LINC01551,CELF3,ZNF92,NFIX,ENPP2,CARF,ARMH4,URGCP,SLC8A1,SORCS3,ANKRD36,RIMS1,C11orf87,WDR7,RGMB,PRMT8,TUBB1" MicroRNA hsa-miR-3192-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-16 1.56E-12 5.09E-16 4.69E-15 52 277 "TRMT9B,CDC14B,ASPA,AP1M1,FOXK1,CDR1,CHRNB2,EPS15L1,BTF3L4,COL9A2,MFSD4A,RGS6,GAPVD1,SGSM2,SYT15,RASA4,MRNIP,MTSS1L,VPS26C,TRMO,KBTBD12,MTHFD2,DISC1,CRCP,GLUL,POLL,KAT7,BVES,DDX19B,SCRG1,ZNF491,NEGR1,ATCAY,IBA57,MAT2A,NBL1,BEST3,PKD1,PTPA,QDPR,IQSEC3,PGBD4,FBXW7,HES6,PEX26,ATF7IP,ZCCHC24,AJAP1,SSBP2,VAV2,ZBTB38,TMEM63C" MicroRNA hsa-miR-23a-3p:Functional MTI Functional MTI miRTarbase 2.78E-16 1.56E-12 5.10E-16 4.70E-15 49 249 "ADD3,NLGN4X,ZNF578,APAF1,ZBTB10,HIP1R,SOCS6,HAPLN1,DOCK4,TMEM170A,PDCD6IP,FSD1L,EN2,FOXM1,FOXO3,CELF1,MPP6,NEK6,ADAM28,PPARGC1A,TXNL4A,GLS,TNRC6A,KLF12,HSP90AA1,IL6R,MEF2C,SNTG1,CAMKV,PIK3R1,PKM,ZNF426,CRLS1,PPP2R5E,ZIK1,ACSS3,BSDC1,SLC6A15,ATAT1,SEMA6D,FNIP1,PEX26,ERBIN,TPM3,TSC1,RPL7L1,ZNF138,CSDE1,JMJD1C" MicroRNA hsa-miR-1248:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.15E-16 1.77E-12 5.79E-16 5.33E-15 39 163 "RALGAPA1,XKR4,FMNL2,RNF157,ADD1,NLGN4X,SPOP,SFMBT2,B4GALT6,PLCXD3,TM9SF4,SCRN1,IP6K1,CPEB2,OPTN,MRO,EMX2,EPHB1,ST3GAL6,ZMAT1,GFRA1,DIPK1C,HMGB1,NEGR1,NPTX2,NUCB1,PDE1B,RASGEF1B,PRKCB,ZYG11B,KCNIP3,BTBD7,MAPK8IP3,EXOC7,SZT2,TNS1,TPD52L2,MEAF6,RNF146" MicroRNA "TCCAGAT,MIR-516-5P:MSigDB" "TCCAGAT,MIR-516-5P:MSigDB" MSigDB 3.25E-16 1.83E-12 5.97E-16 5.50E-15 31 103 "GPRASP2,MIER1,NCOA1,ATP2A2,BCL7A,SPAG9,NUMBL,CSF1,DBN1,SRGAP3,RBM12,RASGRP2,EPHB1,SEMA4D,STAG2,GNAS,NR3C1,ADAMTS6,NCOA7,MMP16,ACER3,KCNIP2,ATXN1,FHOD3,IQSEC2,TAB2,ARHGEF12,LRRC8A,NSD2,SNX27,PHTF2" MicroRNA hsa-miR-496.1:TargetScan hsa-miR-496.1 TargetScan 3.27E-16 1.84E-12 6.01E-16 5.53E-15 32 110 "ATP2A2,CD86,CDH2,MS4A7,ARHGEF6,PLCXD3,CALCRL,EPB41L1,ANKFY1,GABRB1,PTPRT,KLF12,MBNL1,SAMD5,NOVA1,PBX1,PDE3A,FTO,LRP12,PRKACB,PTPRB,RFX3,CSRNP3,ATXN1,ELMO2,LIMCH1,MYT1L,HECW1,NPAS3,GPRIN3,FLRT2,PARP6" MicroRNA hsa-miR-325:PITA hsa-miR-325:PITA_TOP PITA 3.34E-16 1.87E-12 6.12E-16 5.64E-15 25 65 "CDH2,ACBD5,EDN1,CELF1,STAU2,DNER,GPM6A,TPPP,GRIA4,GPR85,CCSER2,TTLL7,RORB,FAM19A1,SLC1A2,RIMS1,TMCC1,SOX5,CDK19,SYT1,ANKRD28,ARHGEF12,RIMBP2,WNK1,WNK3" MicroRNA hsa-miR-383-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-16 2.05E-12 6.69E-16 6.16E-15 66 420 "XKR4,PLEKHH1,TRMT9B,STX16,SYNJ2,REPS2,LONRF2,AKAP5,USP6NL,DNAL1,SLC29A4,MRO,ABI2,PLEKHA1,ING4,IGSF6,TMEM164,ANKFY1,PNMA2,CACFD1,BVES,IRAK3,MATN3,PPM1L,ZC3H12B,OLR1,ZNF713,PDPK1,GPSM2,STRN3,FAT3,APTX,MTMR10,RAB5B,CEP97,ZMAT4,C12orf49,ELP2,R3HDM2,CLSTN1,SLC1A2,SLC2A5,SEPHS1,INAVA,MCF2L2,SS18,ZSCAN29,NEK4,SLC37A2,FAM208A,CLASP1,TJP1,CBX5,ERCC6L2,TUBB2A,RPL7L1,ZNF708,ZNF17,ZNF45,DHX33,EVI5,STOX2,URM1,WIPF2,FBXO36,ZDHHC20" MicroRNA hsa-miR-7703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-16 2.09E-12 6.82E-16 6.28E-15 71 474 "XKR4,SLC12A5,SLC24A4,HACE1,KIAA1324,TXNDC16,PHF12,AMER3,AQP6,CDC14B,CDK5R1,JAZF1,ZNF555,SLC16A4,ZNF445,NRXN3,COL9A2,CLOCK,SUSD5,UBXN2A,TMEM170A,DNAL1,HP1BP3,MTX3,MRO,EPB41,ATP13A4,ANKFY1,TRMO,FUT9,ZNF234,COPS8,GPR75,KIAA1958,KIF3A,MFSD2A,AGBL5,DOCK7,KCNN3,CHST6,CCDC80,PABPC1L2A,ZC3H12B,SLC11A2,ZFYVE21,TATDN3,MAPK8,STK32A,TMEM145,ZNF844,KLHL11,KLHDC8A,ALG9,ATAT1,IL17RB,MAGI3,SEPHS1,FAM126B,EMC1,MCF2L2,C3orf70,ARL10,PPIL6,SSBP2,ZNF610,UBC,USP1,TBC1D15,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-4668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.78E-16 2.13E-12 6.94E-16 6.39E-15 40 172 "SPOP,TRMT9B,USP28,ASGR1,BMPR1B,CCNT1,QKI,HS3ST5,CENPL,FBXO25,GUCD1,RCAN1,EDN3,FSD1L,EIF4G2,CEP85L,TMEM164,AMOTL2,IP6K2,ST6GALNAC3,BRPF3,FAXC,CRCP,GPR75,GPR22,RNF165,HAS2,USP51,MEIS1,ST8SIA5,CLIP1,FNDC3A,SLC8A1,IGSF9B,ARC,TACC1,CBX5,PITPNB,LYPD6,PRDM2" MicroRNA "GGGATGC,MIR-324-5P:MSigDB" "GGGATGC,MIR-324-5P:MSigDB" MSigDB 3.83E-16 2.15E-12 7.02E-16 6.46E-15 22 49 "ARID1A,MAP4K3,APP,ADGRB1,NIPBL,ING4,GGT7,BACH2,KCND2,NTRK3,PBX1,CAMKV,SEPT4,PRKCG,FBXO11,TMCC1,ZHX3,SEPT3,THRA,ZFP91,NSD2,GAN" MicroRNA hsa-miR-214-3p:Functional MTI Functional MTI miRTarbase 3.84E-16 2.16E-12 7.03E-16 6.48E-15 44 206 "ELFN2,CASKIN1,SFMBT2,PDXK,ZBTB10,BCL2L2,LDLRAD4,QKI,TBPL1,CS,NCAN,SOCS5,RUBCN,DAPK1,HEYL,ING4,FGFR1,SEMA4D,FAM49B,NPTN,DKK3,MTHFD2,GNAL,MEF2C,PPM1L,KCTD15,PLXNB1,MAPK8,CNNM2,RAB5B,SCN4B,ABLIM3,CPEB4,ERC1,KIF1B,DOCK9,TPM3,TRPS1,LRTM2,CADM1,RPL7L1,BCL2L13,VAV2,GDPD5" MicroRNA hsa-miR-646:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-16 2.18E-12 7.11E-16 6.55E-15 49 251 "TAOK1,TRMT9B,CASK,MTMR3,FOXK1,CA8,CANX,CCNT1,DLGAP3,TMEM184B,BAG4,CSNK1E,SOCS5,KIAA0408,YTHDC1,POM121,DMTF1,FEM1B,PLEKHA1,DLC1,PCYOX1,NPTN,ELOVL5,IRF8,MYO5A,OCRL,OLR1,PCMT1,PIK3R1,PSAT1,PPP2R5C,CNNM2,PTPRD,ZFHX4,SETD5,TMEM100,SALL1,ZFP30,FNDC3A,MPRIP,KANK1,GPRIN3,ZMAT3,ZNF106,DHX33,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-6745:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.00E-16 2.25E-12 7.32E-16 6.75E-15 42 189 "PNMA8B,TAOK1,PDZD4,BCL7A,ZNF445,CSNK1E,GAPVD1,PHF19,RASSF2,SIRPA,SGSM2,GNE,ABI2,PLEKHA1,ZNF549,MRPL10,ECSIT,RNPS1,GNG4,CECR2,GRIN2D,HMX1,NFIX,NUCB1,PKM,PLCD1,PLEC,RETREG2,PACSIN1,RAB5B,CEP97,PRRT2,SETD5,MYH14,GALNT10,MAGI3,TPCN2,TPM3,SSBP2,UBTF,SLC38A1,EVI5" MicroRNA hsa-miR-933:mirSVR_highEffct hsa-miR-933:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.21E-16 2.37E-12 7.71E-16 7.10E-15 30 97 "PHYHD1,CFLAR,CAMK2G,MAGI1,PPT2,MAP4K4,LETMD1,ZNF521,CCDC144A,TCAF1,KIF19,RCAN2,SUCO,CELF1,GRIA2,LINC00839,TMEM25,IRAK3,CDK14,HERC2P3,MRAP2,RPE65,SCN3A,IFT122,SP4,KDM4C,COBL,PPIL6,DCBLD1,FLRT2" MicroRNA hsa-miR-1250:mirSVR_highEffct hsa-miR-1250:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.33E-16 2.43E-12 7.93E-16 7.30E-15 35 133 "ACTN1,SLC12A5,GPR158,GPAM,LGI1,MAGI1,TIGD7,CHN1,JAM2,SLC35F1,VCAN,SLITRK5,KIAA0753,KLHL5,SRRM1,FCGRT,CAMSAP1,GLS,LOXL3,GAREM2,MRPL42,PAK3,TMEM260,RFX4,TCP11L1,ATXN7,WDTC1,SS18,RELL2,TPD52,LGI4,ZNF17,REEP1,RGS7BP,ADAMTSL3" MicroRNA hsa-miR-4652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-16 2.46E-12 8.00E-16 7.37E-15 32 111 "ARID1A,SPOP,TNRC6C,MIER1,SFMBT2,RASL11B,NIPA1,FOXN3,LRIG1,TMEM130,DPP6,DNAJB6,RASGRP1,EIF4G2,MRNIP,TAOK3,FOXG1,SYNCRIP,FAXC,GRIK4,NR3C1,KLF12,NCAM2,KSR2,GLIPR1L2,PDE3A,PKIA,TTLL7,SOX1,BDP1,WNK1,SLC38A1" MicroRNA hsa-miR-504:PITA hsa-miR-504:PITA_TOP PITA 4.41E-16 2.48E-12 8.06E-16 7.43E-15 31 104 "ZNF608,CANX,FMNL3,CNTFR,RCHY1,ERC2,IP6K1,PLEKHA1,EPHB1,CHL1,PCDH17,RND1,PRRC2B,TMEM121B,IL1RAPL1,ATXN2L,BACH2,KCNK2,INSYN2,NFIX,CNOT4,PDPK1,MINDY2,PKN2,SMPD3,COPZ1,SNCA,MYT1L,LRRC8A,RBFOX2,TSC1" MicroRNA hsa-miR-1229-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-16 2.60E-12 8.47E-16 7.81E-15 44 207 "ACLY,FMNL2,ZNF687,ALS2,FOXK1,LRBA,LETMD1,CTNND1,TM9SF4,AIF1L,JAKMIP2,ABCC5,EIF4G2,SORBS3,EML1,EPB41L2,TUBA1B,MAD2L2,CELF1,AHCYL1,NEU3,SRCAP,ACOT7,HNRNPK,SCAMP5,MPP2,ZDHHC22,KCTD15,PBRM1,C12orf49,HUNK,SAFB,SFPQ,ERC1,SUPT5H,DNAJC9,RPGRIP1L,PITPNB,ZNF781,ZNF195,PMEPA1,CSDE1,HNRNPA3,NETO2" MicroRNA hsa-miR-99b:mirSVR_lowEffct hsa-miR-99b:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 4.68E-16 2.63E-12 8.56E-16 7.88E-15 40 173 "ZFAT,CPNE5,ARNTL,BMPR1B,MTMR3,CA4,LURAP1,NIPBL,EDRF1,DBI,PLPPR4,EPB41L1,CAP2,NOP56,SESN1,ADAM28,DOCK7,INSM1,KCNJ11,LSS,MOG,MYO7A,BEST3,PURG,ING3,PRKCZ,EPDR1,PTPRN2,TTLL7,FBXO11,SLC8A2,SLC14A1,MYO16,KDM4C,TSPYL2,ST5,ANKRD28,DNMBP,UBE3A,VLDLR" MicroRNA hsa-miR-369-5p:mirSVR_lowEffct hsa-miR-369-5p:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 4.81E-16 2.70E-12 8.78E-16 8.09E-15 45 216 "ANK3,SPTBN4,SGCE,SLC25A14,SYT6,VSTM2A,ZFP28,GIT2,ZEB2,ELAVL4,CALCRL,ZSCAN30,ATP13A4,TMEM107,GABRA2,GPD2,PCLO,AP4S1,KIF5C,SFR1,NOS1,HCN1,NLE1,MAPK9,PTPRE,RGS7,KLHL11,ACER3,ATAT1,NCBP3,SALL1,SCN4B,LINC00461,HKDC1,DZIP1,SLC14A1,SOX2,COBL,TBX15,RALYL,TIAM1,HIRA,FLRT1,HPS4,JMJD1C" MicroRNA hsa-miR-6828-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.94E-16 2.77E-12 9.02E-16 8.31E-15 37 149 "SLC24A4,OGT,USP37,ATP1B3,BCL7A,FMNL3,MYOM2,PPP1R16B,PHF19,EPB41,ZNF391,ZNF585B,DLC1,FOXO3,TMEM151A,ZMYND11,NCKAP1,CYP46A1,ZNF678,MITF,PLXNB1,PACSIN1,SETD5,ZNF331,R3HDM2,TMCC1,WDTC1,SYPL1,TAF6,TRIM2,BHLHB9,SMUG1,TUBB2A,BCL2L13,MEAF6,FBXO36,SPATA13" MicroRNA hsa-miR-939-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.29E-16 2.97E-12 9.67E-16 8.91E-15 43 199 "CPNE2,AP1B1,CASKIN1,AMPD2,ARMC12,ARRB1,ASPH,DIRAS1,CBS,TMEM184B,RGS6,PHYHIP,PLEKHM1,ABCC5,ING4,AMOTL2,HBS1L,SRCAP,TNFAIP8L3,HMX1,SHISA6,SOWAHA,KIF5A,MSI1,NBL1,GPR173,PTPA,C12orf49,RPS6KA2,SH3BP2,CLSTN1,LHFPL4,ERC1,NFASC,CLSTN2,CAMTA2,SEPT8,FAM168A,SLC19A3,CBX5,RPRM,UBTF,HNRNPA3" MicroRNA hsa-miR-605-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.58E-16 3.13E-12 1.02E-15 9.38E-15 35 134 "SDE2,TMCC3,RNF157,HECW2,ARRB1,BTRC,FOXK1,CANX,CBFA2T2,CD81,AKAP5,CTNND1,FAM131B,BLOC1S6,PHC2,MTSS1L,MALT1,STARD3,ZNF496,IRAK3,NLE1,PMP22,TNPO2,TMEM104,RAB5B,SBF1,IL17RB,SMARCE1,MAPKBP1,ZSCAN29,SATB2,USP22,ZNF106,ZNF74,URM1" MicroRNA hsa-miR-6128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.78E-16 3.25E-12 1.05E-15 9.71E-15 30 98 "BEND6,NLGN4X,ATP1B3,CANX,CLCN3,TMEM184B,RIMS4,DCAF4,SNX29,ABI2,BSCL2,EPB41,COQ7,TMEM151A,CRCP,GNAS,NUDT21,CYP27C1,C1orf109,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,AGTPBP1,TMPO,PPIL6,SSBP2,NDRG4,SLC30A4" MicroRNA hsa-miR-362-5p:TargetScan hsa-miR-362-5p TargetScan 6.01E-16 3.38E-12 1.10E-15 1.01E-14 36 142 "ABR,ADCYAP1R1,NOL4,CDK5R1,DST,NRXN3,RIMS4,ABI2,ERBB4,MRVI1,CORO2B,RAPGEF6,NCKAP1,LOXL3,KCNN3,KIF2A,PAK3,FAM216A,PLP1,PLXNB1,CDIP1,MED1,EPDR1,PROX1,PTPRD,GTDC1,HUNK,RMI1,CPEB4,PEG10,ADHFE1,ATMIN,ARHGEF12,FAM47E,HNRNPA3,GAN" MicroRNA hsa-miR-4723-5p:Functional MTI Functional MTI miRTarbase 6.37E-16 3.58E-12 1.16E-15 1.07E-14 49 254 "RNF157,HACE1,SORCS2,TAOK1,ANK1,PPFIA3,PRX,CAMK2A,METTL6,DLGAP3,TMEM184B,CRMP1,PLEKHM1,EFNA3,EIF4G1,ANKRD13B,WAC,AFF2,CELF1,PRRC2B,KCNH2,CHST6,NDUFA5,NEUROD2,NRGN,CCSER2,PKM,SPATA6,PTPA,DIRAS2,BDNF-AS,PRRT2,SETD5,MYH14,EMID1,SMTN,PKNOX2,FNBP1,ERC1,RAP1GAP2,NFASC,USP22,HHIP,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-625-5p:Functional MTI Functional MTI miRTarbase 6.95E-16 3.91E-12 1.27E-15 1.17E-14 46 227 "ADAR,TAOK1,ANK1,ARHGDIA,CALM1,CAMK2A,METTL6,DLGAP3,TMEM184B,PLEKHM1,DUSP9,EFNA3,GPR61,ANKRD13B,MTHFD2,GLUL,PRRC2B,NXPH3,KCNH2,CHST6,MDM4,SESN3,NFIX,NTRK3,BEST3,PKM,ZNF426,SPATA6,TNPO2,PTPA,DIRAS2,BDNF-AS,IQSEC3,MYH14,SHMT2,PKNOX2,WDTC1,SOX2,FNBP1,RAP1GAP2,ZNF34,TUBB2A,UBTF,CLIP2,RICTOR,ITM2C" MicroRNA hsa-miR-5690:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.95E-16 3.91E-12 1.27E-15 1.17E-14 46 227 "AS3MT,SLC24A4,TXNDC16,APAF1,AQP6,CDC14B,ZNF583,CANX,SLC16A4,CBFA2T2,NRXN3,ENTPD4,IPCEF1,UBXN2A,MYADM,ELMSAN1,FBXL5,MAGI2,GNE,MRNIP,ZNF585B,ZNF589,SMC2,DOT1L,GPR75,PRRC2B,BVES,AGBL5,IBA57,KCNJ5,KLHL23,FGFBP3,NUCB1,TTC13,SLC25A36,NCBP3,DRAXIN,SEPHS1,INKA2,KIAA1107,TRIM2,AKNA,TPM3,ZNF154,ACTR3B,RNF146" MicroRNA hsa-miR-610:PITA hsa-miR-610:PITA_TOP PITA 7.17E-16 4.03E-12 1.31E-15 1.20E-14 33 120 "SEMA4G,BCL2L2,MTMR3,KIAA1549L,FAM19A5,COL4A5,MAGI2,DMD,EBF1,PLEKHA1,PAN3,SRRM1,GAB1,CIT,ELOVL5,JAK1,PTPRD,RNF220,ROBO2,SGK1,PPM1E,BTBD3,SLC8A1,TET1,PALLD,NKAIN2,STXBP1,NECAB1,ANKRD12,ZNF384,SLAIN1,RGS7BP,HNRNPA3" MicroRNA "GCTCTTG,MIR-335:MSigDB" "GCTCTTG,MIR-335:MSigDB" MSigDB 7.23E-16 4.06E-12 1.32E-15 1.21E-14 27 79 "SORCS1,CERS5,NRXN1,FAM131B,LONRF1,FAM107B,ABCC5,PHF20L1,GLYR1,KDM2B,KAT7,ZHX1,ARHGAP12,MAP2,PCDH9,ZDHHC8,EPB41L4B,POU6F1,BSDC1,ZSWIM8,KDM4C,SYN2,PSD3,RPRM,UBE2H,VAV2,POLR3H" MicroRNA hsa-miR-363-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.25E-16 4.07E-12 1.32E-15 1.22E-14 42 192 "PNMA8B,TAOK1,PDZD4,BCL7A,ZNF445,CSNK1E,GAPVD1,PHF19,RASSF2,SIRPA,SGSM2,GNE,ABI2,PLEKHA1,ZNF549,MRPL10,ECSIT,RNPS1,GNG4,CECR2,GRIN2D,HMX1,NFIX,NUCB1,PKM,PLCD1,PLEC,RETREG2,PACSIN1,RAB5B,CEP97,PRRT2,SETD5,MYH14,GALNT10,MAGI3,TPCN2,TPM3,SSBP2,UBTF,SLC38A1,EVI5" MicroRNA hsa-miR-222-3p:Functional MTI Functional MTI miRTarbase 7.26E-16 4.08E-12 1.32E-15 1.22E-14 63 394 "RBM10,ARID1A,AP1B1,APP,FUBP1,CANX,CAST,NFS1,CDC27,ZFYVE9,ABCG2,QKI,MROH8,SEC24C,ZFYVE16,DBN1,ZEB2,POM121,SV2A,TOM1,PLXNC1,EPB41L2,FOXO3,SMC2,ZMYND11,TCERG1,RNPS1,GRB10,FICD,HSP90AA1,KIF5C,KIT,IPO5,STMN1,MAT2A,KITLG,DBNL,CDK18,OLA1,PKM,NLE1,EXOSC10,UBR7,SLC25A36,YY1AP1,CASC3,ZFP30,ZFP1,SMARCA4,TMCC1,FAM126B,SON,RAP1GAP2,SS18,GANAB,SLC19A3,DICER1,TP53BP2,TRPS1,ZNF708,ZFAND5,STOX2,CIAPIN1" MicroRNA hsa-miR-3927-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.06E-16 4.53E-12 1.47E-15 1.35E-14 41 184 "MTUS1,ZNF578,FAM135A,AQP6,DYNLL1,ALDH4A1,CRY2,CTNND1,MTX3,DNAH9,MAMLD1,E2F6,EDN1,SH3GLB1,EIF4G2,MRNIP,DISC1,GATM,POLL,RABL2A,SLC35G1,KPNA5,NAT8L,MDM4,SLC11A2,BEST3,QDPR,FIGN,ARMH4,CSRNP3,HSPA4L,MAPKBP1,NSD1,AHCYL2,CBX5,TUBB2A,ZNF28,SMARCAD1,CSDE1,C12orf4,FXR1" MicroRNA hsa-miR-6836-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.11E-16 4.55E-12 1.48E-15 1.36E-14 44 210 "MTA3,GYG2,CACNA1A,RAB3C,IGLON5,RTTN,KIAA0408,TMEM170A,KIAA0319,RABGAP1L,DYRK1A,KRBA2,CNNM1,RGS17,TESK2,FLYWCH1,PDLIM5,MSANTD4,RAB40B,NXPH3,DDX19B,NKD1,KCNK1,LIMS1,GPR155,MOG,NUCB1,FITM2,PIGG,STX1B,GALNT10,PEX26,LRRC55,FAIM2,TROVE2,AJAP1,FGD4,AGTPBP1,PCDHA6,ARL10,ERCC6L2,FAM124A,PARD3,AGMO" MicroRNA hsa-miR-6870-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-16 4.96E-12 1.61E-15 1.48E-14 49 256 "RNF157,HACE1,SORCS2,TAOK1,ANK1,PPFIA3,PRX,CAMK2A,METTL6,DLGAP3,TMEM184B,CRMP1,PLEKHM1,EFNA3,EIF4G1,ANKRD13B,WAC,AFF2,CELF1,PRRC2B,KCNH2,CHST6,NDUFA5,NEUROD2,NRGN,CCSER2,PKM,SPATA6,PTPA,DIRAS2,BDNF-AS,PRRT2,SETD5,MYH14,EMID1,SMTN,PKNOX2,FNBP1,ERC1,RAP1GAP2,NFASC,USP22,HHIP,THRA,RPRM,UBTF,MGAT5B,CLIP2,RICTOR" MicroRNA hsa-miR-6766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.30E-16 5.22E-12 1.69E-15 1.56E-14 48 247 "TAOK1,IGDCC4,BCL7A,CCNT1,ZNF445,CACNA2D2,DLGAP3,ZNF385A,CSNK1E,PHF19,IP6K1,SIRPA,PLEKHM1,E2F6,ABI2,PLEKHA1,ANKRD13B,DOT1L,AHDC1,RNPS1,TNRC6A,PRRC2B,SOWAHA,KCNK3,MDFI,MPP2,ZC3H12B,NFIX,NKX2-2,NUCB1,PKM,EPN1,SPATA6,PPARA,RAB5B,CEP97,PRRT2,SETD5,KLHDC8A,ATXN2,MAGI3,UNC5B,TPCN2,TPM3,UBTF,ZNF708,SLC38A1,GAN" MicroRNA hsa-miR-136*:mirSVR_highEffct hsa-miR-136*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.37E-16 5.26E-12 1.70E-15 1.57E-14 39 168 "KLHL32,UNC79,LINC00173,BACH1,KALRN,CANX,CAST,INA,SRSF11,AKAP12,DDX46,DLG2,HS3ST2,DYRK1A,SIRPB1,SEC24B,OLFM1,PSD2,ZMYND11,GNAS,B4GALNT4,PCLO,STMN2,HAS2,UBE2QL1,KCNJ3,MBD1,MIA2,CNTLN,DBX2,TMEM100,SCG5,NTNG1,SLC14A1,SNRPN,ADHFE1,MTCL1,ZBTB16,NUP214" MicroRNA hsa-miR-873-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.69E-16 5.44E-12 1.76E-15 1.62E-14 50 266 "ABCF1,ADAR,SLC24A4,SORCS2,ZBTB10,WASF1,DDR1,GPR37L1,CLU,PPP1R16B,CTNND1,IST1,BLOC1S6,SNX29,EN2,KIAA1109,POLR1B,TACC2,HHIPL1,GJB1,GPR75,RABL2A,PACSIN2,SHISA6,ITPKB,KCNH2,KIF5A,LAMP2,MEIS1,TBC1D25,ABCB1,PKM,SMIM7,MTRF1L,PPP2R5E,ALG9,SGK1,SH3BP2,SLC2A5,SP2,ZNF423,ZSCAN29,KANK1,CAMSAP2,MGRN1,ARL10,NACC2,RGMB,VAV2,GDPD5" MicroRNA hsa-miR-937:mirSVR_lowEffct hsa-miR-937:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 9.76E-16 5.48E-12 1.77E-15 1.63E-14 38 160 "SLC12A5,SUGT1P4-STRA6LP-CCDC180,GPR146,LHX2,CRMP1,CTIF,POM121,SLC29A4,SLC43A2,ZIC4,FCGR3A,TOMM40L,SEMA6C,TXNL4A,STMN2,GRIA1,PACSIN2,HSP90AA1,DISP2,KIF5C,MITF,MT3,CCDC13,NOS1,POU3F4,SLC22A23,SLC30A10,ARFGAP1,SNCB,KDM4C,KAZN,NPDC1,ZFP41,POLR3H,STOX2,TMEM178A,SEMA3B,CASC15" MicroRNA hsa-miR-675:mirSVR_highEffct hsa-miR-675:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.01E-15 5.69E-12 1.84E-15 1.69E-14 29 93 "ADGRB2,SYNJ2,CASTOR3,L3MBTL4,NOG,SUMF2,HP1BP3,EPHB1,SRRM1,TUBB4A,KBTBD12,ZNF274,KCNN1,NNAT,SIDT1,WDR25,NKAIN1,ATAT1,NCBP3,DGLUCY,SCN8A,KDM4C,FBXL16,ELP5,TRIO,ZBTB16,RNF103,SEMA3B,CASC15" MicroRNA hsa-miR-193a-5p:PITA hsa-miR-193a-5p:PITA_TOP PITA 1.01E-15 5.69E-12 1.84E-15 1.69E-14 29 93 "KCNH8,DSCAML1,PCDH19,RUNX1T1,DCLK1,ZMYM4,CNTNAP2,FRMPD4,NR1D2,CPEB2,CELSR3,KCNMB2,MAP2,MYO5A,NOVA1,ZNF827,PDE1C,OLA1,CDK14,RELN,ZSCAN32,RBBP6,RGS4,ITSN1,SYT11,ANO4,MKRN3,LAMP5,SLC4A10" MicroRNA hsa-miR-877:PITA hsa-miR-877:PITA_TOP PITA 1.02E-15 5.75E-12 1.86E-15 1.71E-14 32 114 "PCDH19,AMPH,ATP2B1,NEURL1,NMT2,RCHY1,ERC2,TMCC2,DYRK1A,FSD1L,ATP8A1,FOXM1,STAMBP,OGA,AHCYL1,MAP4K5,FRMD3,BRINP3,MN1,ZNF827,PTCH1,TTC13,REV3L,SCN3A,NLGN4Y,LMBRD1,SP4,NMNAT2,PEG10,PRRC2C,NAV3,PHTF2" MicroRNA "TCTATGA,MIR-376A:MSigDB" "TCTATGA,MIR-376A:MSigDB" MSigDB 1.04E-15 5.84E-12 1.88E-15 1.74E-14 27 80 "DSCAML1,ANK2,DCAF5,CAPN3,USP6,SEPT7,NIPBL,CSNK1G3,FAM131B,COPS7A,GRIN3A,SIDT2,KHDRBS3,ZMYND11,FERMT2,GRIK2,GRIK5,HES5,KCNIP2,FBXO11,SLC6A1,MBD5,LARP4,CUX2,ZIC3,CELF4,SLC4A10" MicroRNA "TCTATGA,MIR-376B:MSigDB" "TCTATGA,MIR-376B:MSigDB" MSigDB 1.04E-15 5.84E-12 1.88E-15 1.74E-14 27 80 "DSCAML1,ANK2,DCAF5,CAPN3,USP6,SEPT7,NIPBL,CSNK1G3,FAM131B,COPS7A,GRIN3A,SIDT2,KHDRBS3,ZMYND11,FERMT2,GRIK2,GRIK5,HES5,KCNIP2,FBXO11,SLC6A1,MBD5,LARP4,CUX2,ZIC3,CELF4,SLC4A10" MicroRNA hsa-miR-3131:mirSVR_highEffct hsa-miR-3131:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.07E-15 6.02E-12 1.94E-15 1.79E-14 30 100 "DDX3Y,DNM1L,APH1A,EIF1,CLVS1,SEMA6C,CELF1,DACH2,STARD3,FERMT2,ELOVL5,SMAP1,KIFC3,NLGN3,MTRF1L,TTC13,GTDC1,EXD2,C11orf87,SMOC1,VAMP1,MTCL1,RPGRIP1L,SYNE1,TLR4,RIMBP2,C9orf85,TRPS1,OSBP2,SHD" MicroRNA "CTGTTAC,MIR-194:MSigDB" "CTGTTAC,MIR-194:MSigDB" MSigDB 1.07E-15 6.02E-12 1.94E-15 1.79E-14 30 100 "PITPNM2,ARHGAP5,STX16,MYRF,LRRFIP1,LGI1,QKI,ST18,ELMSAN1,DMD,HS3ST2,DUSP9,MBNL2,PAN3,GABRB3,GYG1,KLF12,TJAP1,MEIS2,PFKFB2,ZFHX4,FBXW7,ITSN1,CHD9,SEPHS1,BTBD7,CDK19,EHBP1,TRPS1,TRIM9" MicroRNA hsa-miR-4643:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-15 6.06E-12 1.96E-15 1.80E-14 40 177 "ADCY2,KCTD16,TAOK1,TNRC6C,CADPS,STX16,CADM3,BACH1,LONRF2,ZFYVE9,BAG4,CRY2,SPOCK2,CPEB2,CERCAM,TUBA1B,MTHFD2,COPS8,GLI2,PADI2,HLF,C5orf24,KLHL23,SYTL4,ZNF827,PIK3R1,PURG,PNMA8A,STX1B,STUM,ZNF415,INKA2,NSFL1C,SYT5,SIK3,HHIP,NR2C2,UBE2H,RTN4,SPATA13" MicroRNA hsa-miR-4524a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-15 6.73E-12 2.17E-15 2.00E-14 55 316 "ABCF1,AS3MT,TEX22,AP1B1,SFMBT2,ARHGDIA,ARSE,ATP1A2,FOXK1,LONRF2,CCPG1,TBRG4,IFFO1,RTTN,SEC14L5,TMEM170A,SPATA2,SGSM2,DNAH9,ST8SIA3,RGS17,TUBD1,SCARA3,PCYOX1,FAM184B,SRRM4,MYOZ2,SRCAP,PPARGC1A,CRCP,OS9,FUT10,SCRG1,ZDHHC15,SCIN,IBA57,MBD1,MOG,NPTX1,GPR173,SMIM7,MINDY2,KANSL1,PKIA,MTMR10,ZYG11B,FIGN,ALG9,USP22,TMEM9,TBC1D15,ZNF74,LYPD6,ZNF177,TMEM198" MicroRNA hsa-miR-6831-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-15 6.75E-12 2.18E-15 2.00E-14 41 186 "MTUS1,ZNF578,FAM135A,AQP6,DYNLL1,ALDH4A1,CRY2,CTNND1,MTX3,DNAH9,MAMLD1,E2F6,EDN1,SH3GLB1,EIF4G2,MRNIP,DISC1,GATM,POLL,RABL2A,SLC35G1,KPNA5,NAT8L,MDM4,SLC11A2,BEST3,QDPR,FIGN,ARMH4,CSRNP3,HSPA4L,MAPKBP1,NSD1,AHCYL2,CBX5,TUBB2A,ZNF28,SMARCAD1,CSDE1,C12orf4,FXR1" MicroRNA hsa-miR-922:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-15 6.82E-12 2.20E-15 2.03E-14 38 161 "ELFN2,FZD9,TRMT9B,MIER1,PDXK,ZBTB10,ATP1B3,CLU,ZFP28,RUBCN,G3BP2,HEYL,GOLGA7,EN2,ATP13A4,FAM49B,NPTN,NCKAP1,MTHFD2,SRRM4,TNRC6A,GRID1,RNFT2,IDH3A,MID1,KCTD15,KIAA0895L,COPZ1,CPEB3,CPEB4,TMEM136,AP4E1,WBP2,UBE2H,CCDC14,ZNF154,GDPD5,XKR7" MicroRNA hsa-miR-215-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-15 6.87E-12 2.21E-15 2.04E-14 33 122 "ADCY2,TEX22,USP37,SFMBT2,ZBTB10,COL9A1,ZSCAN23,DBT,GNE,OPTN,TENM1,TUBD1,FAXC,TPPP,KAT7,KLF12,GPSM2,STRN3,PIGG,MTMR10,ZYG11B,HSPA4L,BDP1,SEPT3,KLHL7,KIAA0930,AP4E1,ZNF34,ZNF106,PITPNB,ZNF74,SPIRE1,SLC38A1" MicroRNA "TGAGATT,MIR-216:MSigDB" "TGAGATT,MIR-216:MSigDB" MSigDB 1.45E-15 8.15E-12 2.62E-15 2.42E-14 30 101 "ARID1A,NCOA1,DCLK1,MATR3,POM121,DRD1,MBNL2,EGR3,ELAVL2,GABRA1,MSL3,EML4,PTPRT,ADAMTS6,JAK2,MMP16,HNRNPM,GPR85,ANKRD16,TNPO2,PPM1B,CPEB4,KDM3A,SP4,ADGRL3,CUX2,RPGRIP1L,ZFP91,VANGL2,NETO1" MicroRNA hsa-miR-487b:mirSVR_highEffct hsa-miR-487b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.51E-15 8.48E-12 2.73E-15 2.51E-14 38 162 "NLGN4X,AMPH,MAP4K3,APP,KALRN,RAB3C,NDST3,KMT2C,RAB28,NGEF,AKAP6,SLC25A27,SNAP91,HS3ST2,DNM1L,GPHN,ARMCX1,STAG2,GRIA2,DIDO1,GRIA4,GRM3,SMAP1,ITPKB,ZNF655,PPM1B,RDX,RPS6KA2,CLIP1,ITSN1,MAGI3,BTBD7,SLC22A4,KAT6B,ZMYND8,ZIC1,CADM2,PAK5" MicroRNA hsa-miR-5582-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-15 8.48E-12 2.73E-15 2.51E-14 38 162 "SDE2,SLC7A14,QKI,CLOCK,C2CD2,CRY2,IPCEF1,SEC14L5,SEC16A,DNAH9,E2F6,POLR1B,ZBED3,B4GALNT4,NR3C1,KAT7,ZNF678,NCAM2,NFIX,KSR2,ATAT1,SBF1,SH3BP2,R3HDM2,BTBD3,SLC8A1,RAB3GAP1,UNC5B,INKA2,NECAB1,SYPL1,TBX15,GALNT17,NSD2,WRN,CLDND1,SIGLEC10,MVB12B" MicroRNA hsa-miR-6832-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-15 8.70E-12 2.80E-15 2.58E-14 50 269 "RNF157,CASKIN1,TAOK1,C6orf89,API5,ATP1A2,BACH1,AKAP6,COL9A2,BAG4,HINFP,SEC14L5,PYGO1,KIAA0513,KIAA0586,GNE,WDPCP,C8orf37,EPB41L1,EPS8,ST6GALNAC3,TRAF3IP2,MYOZ2,ZNF276,POLL,DDX19B,HSP90AA1,KPNA5,GPR155,LAYN,KSR2,PAK3,MINDY2,GDPD1,ZIK1,ZNF793,NWD1,ZYG11B,PRIMA1,ZNF621,ALG1,NSD1,GPRIN3,TPM3,ZNF384,SSBP2,NSD2,ZNF708,ZNF70,ZNF138" MicroRNA hsa-miR-548az-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-15 8.70E-12 2.80E-15 2.58E-14 50 269 "SLC12A5,PTBP2,SRSF11,QKI,TOGARAM2,CLOCK,SOCS5,PYGO1,YTHDC1,CEP170,DPYSL2,EFNA2,KATNAL1,WAC,ACSL4,DLC1,SUCO,TPK1,ZMAT1,SALL3,TNRC6A,PRRC2B,GPM6A,GRB10,MAP4K5,SOWAHA,STMN1,ARHGAP12,TM6SF1,SESN3,CNOT4,PFKFB2,PFKFB3,ST8SIA5,SH3KBP1,SLC25A36,C12orf49,MCMBP,ATAT1,SON,SMOC1,DHX33,CADM2,CSDE1,ADAMTS9,PPP1R3F,ITM2C,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-548t-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-15 8.70E-12 2.80E-15 2.58E-14 50 269 "SLC12A5,PTBP2,SRSF11,QKI,TOGARAM2,CLOCK,SOCS5,PYGO1,YTHDC1,CEP170,DPYSL2,EFNA2,KATNAL1,WAC,ACSL4,DLC1,SUCO,TPK1,ZMAT1,SALL3,TNRC6A,PRRC2B,GPM6A,GRB10,MAP4K5,SOWAHA,STMN1,ARHGAP12,TM6SF1,SESN3,CNOT4,PFKFB2,PFKFB3,ST8SIA5,SH3KBP1,SLC25A36,C12orf49,MCMBP,ATAT1,SON,SMOC1,DHX33,CADM2,CSDE1,ADAMTS9,PPP1R3F,ITM2C,PHTF2,JMJD1C,NETO2" MicroRNA hsa-miR-372-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-15 8.88E-12 2.85E-15 2.63E-14 56 328 "TMEM132B,SLC24A4,TXNDC16,CDK13,MAP7,ZBED1,ZNF445,STOML1,SEC14L5,MYADM,GAPVD1,CENPL,GUCD1,SGSM2,RABGAP1L,FEM1B,ELAVL2,PLEKHA1,ELAVL4,C8orf37,COQ7,RAB9B,FAXC,SRCAP,TNRC6A,FUT10,HAS2,PTGDR2,DDX19B,CHST6,MITF,DBNL,OLR1,PIK3C2A,CCSER2,ZNF426,PTPRN2,DCUN1D2,KLHDC8A,SGSM1,FNBP1,SP4,KIF1B,ADAMTS17,TMEM136,SLC19A3,VWCE,ZNF34,TMPO,RIMBP2,TRPS1,TUBB2A,TOM1L2,VLDLR,ZNF24,WIPF2" MicroRNA hsa-miR-5197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-15 1.05E-11 3.38E-15 3.11E-14 38 163 "AK2,SEMA7A,ARMC12,MIER1,SFMBT2,HAP1,CDC27,GPR37L1,C4orf33,ARHGEF6,VCAN,RIMS3,TOMM20,FAM107B,TNRC6A,RNF165,RABL2A,NAT8L,MOG,COMMD5,GPR173,PACSIN1,PTPA,RAB5B,FIGN,SLC25A36,RPH3A,BTBD3,ERBIN,MAPK8IP3,SATB2,AHCYL2,ZFP91,TPD52L2,RPRM,WRN,WIPF2,FRMD6" MicroRNA hsa-miR-5003-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-15 1.07E-11 3.43E-15 3.16E-14 35 139 "RNF150,NLGN4X,OSBPL1A,ABCD2,USP28,USP37,CSNK1G3,VCAN,MAML1,PITPNC1,EBF1,FEM1B,SARAF,HHIPL1,GABRB1,HBS1L,SYT17,NUDT21,HAS2,CLVS2,KCNN3,L1CAM,LIFR,NEUROD1,GLIPR1L2,STRN3,NWD1,ZFHX4,CCDC25,LRRC55,ZBTB43,SGK3,ZNF610,WRN,ZBTB38" MicroRNA hsa-miR-23b-5p:Functional MTI Functional MTI miRTarbase 1.94E-15 1.09E-11 3.50E-15 3.22E-14 37 155 "AS3MT,SLC4A4,DDR1,ZNF385A,CSNK1E,ZBTB24,RABGAP1L,RGS17,TUBD1,FOXO3,NCKAP1,CNDP1,SCRG1,SLC35G1,CAMK2N2,LIMS1,PPM1L,MOG,SAMD5,FITM2,PRODH,APTX,ZSCAN2,GTDC1,ALG9,PGBD4,HSD11B1L,AMBRA1,WDR37,PEX26,SP2,AGTPBP1,ARL10,SSBP2,LMAN2L,NAV2,LINC00632" MicroRNA hsa-miR-23a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.94E-15 1.09E-11 3.50E-15 3.22E-14 37 155 "AS3MT,APAF1,SLC4A4,DDR1,ZNF385A,CSNK1E,ZBTB24,RABGAP1L,RGS17,TUBD1,FOXO3,NCKAP1,CNDP1,SCRG1,SLC35G1,CAMK2N2,LIMS1,PPM1L,MOG,SAMD5,FITM2,APTX,ZSCAN2,GTDC1,ALG9,PGBD4,HSD11B1L,AMBRA1,WDR37,PEX26,SP2,AGTPBP1,ARL10,SSBP2,LMAN2L,NAV2,LINC00632" MicroRNA hsa-miR-4671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-15 1.10E-11 3.52E-15 3.25E-14 30 102 "ADD1,ABCD2,PHF12,CAPRIN2,CLCN3,TPP1,ACBD5,DAPK1,CEP170,DLC1,SEC23B,FLT1,MSANTD4,MALT1,PRUNE2,ZIC5,ZNF678,PURG,PTPRG,UEVLD,CLIP1,CDK19,SPART,TROVE2,ZMAT3,THRA,TRPC3,ZNF24,ZNF154,WIPF2" MicroRNA hsa-miR-6809-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-15 1.10E-11 3.52E-15 3.25E-14 30 102 "PHF12,CCNT1,PUM1,LIN54,DNM2,E2F6,PHC2,TACC2,CRCP,PRRC2B,LILRA2,RAPGEF1,HMGB1,RBPJ,ZNF678,PPM1L,GPR137C,PSD,ZIK1,RAB5B,SETD5,MCMBP,FNDC9,CLASP1,NSD1,SLC44A1,RPL7L1,UBTF,CLDND1,DPYSL5" MicroRNA hsa-miR-3685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-15 1.10E-11 3.52E-15 3.25E-14 30 102 "ADD2,GAS7,MARK4,ATP1A1,SYT6,RUNX1T1,LONRF2,CNN3,CREB5,EN2,EPB41,COQ7,CDHR1,MRVI1,SMC2,SRRM4,GPR155,SESN3,NFIX,KANSL1,MARCH1,KIRREL1,SCN2B,ZFP30,ST6GAL1,TCF7L2,TPM1,TRPS1,RICTOR,WNK1" MicroRNA hsa-miR-493:PITA hsa-miR-493:PITA_TOP PITA 2.11E-15 1.18E-11 3.79E-15 3.49E-14 27 82 "RTL9,CADPS,DDX3Y,ATP1B3,ATP2B1,ADGRB3,SRSF11,SLC35F1,DLG3,EIF4G2,TMEM35A,TESK2,TBR1,CPLX1,RAB30,TNRC6A,KDM2B,SOX21,NCKAP1L,IGF1,KCNMA1,ZNF827,GNG2,SETD5,MCMBP,RCOR3,PAK5" MicroRNA hsa-miR-5680:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-15 1.22E-11 3.89E-15 3.59E-14 41 189 "DDX3Y,ARHGEF7,CSNK1E,UBXN2A,CTNND1,TMEM170A,FBXL5,DYRK1A,EIF4G2,TENM1,DLC1,SYNCRIP,ZBED3,STAMBP,CAB39,WASF3,ADAP1,IL6R,NCOA7,MAT2A,MBNL1,CCDC80,OPHN1,PRKAB2,PTPRN2,ERI2,FIGN,MYH14,CSRNP3,BTBD3,SLC6A8,KIF13A,SEPT8,ATP11A,TCEA1,SATB2,TPD52,TUBB2A,VLDLR,ZNF711,SMARCAD1" MicroRNA hsa-miR-25*:mirSVR_highEffct hsa-miR-25*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.28E-15 1.28E-11 4.10E-15 3.78E-14 34 132 "LRFN2,AMPD2,SUGT1P4-STRA6LP-CCDC180,MARCH3,CST3,DPH1,SRRM1,ZNF589,CAP2,RASL10A,ATP6V1H,GHR,NRBP2,NCAM2,PAK3,APTX,BSDC1,RGS3,KCTD17,TMLHE,UEVLD,RPS20,KANSL3,KDM4C,FAM168A,ACSBG1,PRRT1,SEZ6L,SSBP2,ANKS1B,PRTFDC1,PPP1R3F,ST7,CBLN2" MicroRNA hsa-miR-513a-5p:Functional MTI Functional MTI miRTarbase 2.37E-15 1.33E-11 4.27E-15 3.93E-14 43 207 "SLC25A25,ADD1,AK2,GPAM,IGDCC4,ARNTL,PNKD,CRY2,RGS6,CTNND1,LONRF1,LIN54,NR1D2,DUSP9,MAMLD1,EN2,TOMM40L,GTF2IRD2,SUCO,NPTN,CELF1,NUDT21,MIER3,SLC6A17,LIFR,MITF,MKLN1,HS6ST3,OLR1,BDNF-AS,ALG9,SEMA6D,COPZ1,FNDC3A,ERC1,PEG10,GSE1,TGFBR3,ZNF106,ZNF384,ZBTB38,AP3B2,SPATA13" MicroRNA hsa-miR-676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-15 1.42E-11 4.53E-15 4.18E-14 31 110 "TAOK1,PARG,TNRC6C,IPCEF1,UBXN2A,RABGAP1L,EDIL3,FCF1,SCML2,PCYOX1,C10orf105,MXI1,MYBPC1,NPTX1,FAM98B,CCSER2,POLG,PTPRN2,ZNF793,RAP1GDS1,ZDHHC14,GALNT10,LIMCH1,PEG10,DIP2A,TBL1X,ASXL3,FNDC5,PITPNB,PRDM10,PHTF2" MicroRNA hsa-miR-1973:mirSVR_highEffct hsa-miR-1973:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.52E-15 1.42E-11 4.53E-15 4.18E-14 31 110 "SLC24A4,BCAS1,BARD1,LRRFIP1,CASC2,CLU,VCAN,DAPK3,MAGI2,USP3,MBNL2,FLNC,GLI2,GPD2,GRIA4,TNFAIP8L3,LDLRAD3,MEIS2,MIA2,LAYN,PCDH9,EPDR1,PSMD13,LRRK2,HOGA1,SHC4,TBX15,CDH22,PRMT8,ZMYND8,TMEM198" MicroRNA hsa-miR-346:PITA hsa-miR-346:PITA_TOP PITA 2.58E-15 1.45E-11 4.64E-15 4.27E-14 25 70 "FAM131A,CADM3,RBM39,RIMS2,DGKG,MYEF2,DLG2,PRRC2B,GRM7,PTPN5,ADAMTS6,KIF5C,MBNL1,NXPH1,PKIA,RDX,SLC25A36,SORCS3,PEG10,NCDN,AJAP1,CCDC136,SF1,ZIC1,HRASLS" MicroRNA hsa-miR-4476:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-15 1.55E-11 4.97E-15 4.57E-14 42 199 "SDE2,ELFN2,TAOK1,SEMA4G,ALDH4A1,CNN3,IFFO1,IP6K1,DBN1,SPATA2,PHC2,EN2,F3,AMOTL2,SUCO,STARD3,PRRC2B,ZNF496,TNFAIP8L3,KCNJ10,MAG,ZFYVE27,BLOC1S2,PABPC1L2A,NOVA2,ZNF426,PACSIN1,PTPA,RAB5B,TRIM67,SMARCE1,FAM168A,SYPL1,USP22,NACC2,WBP2,RGMB,TMPRSS5,UBTF,TSPAN11,WRN,NAV2" MicroRNA hsa-miR-6876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-15 1.55E-11 4.97E-15 4.57E-14 42 199 "SDE2,ELFN2,TAOK1,SEMA4G,ALDH4A1,CNN3,IFFO1,IP6K1,DBN1,SPATA2,PHC2,EN2,F3,AMOTL2,SUCO,STARD3,PRRC2B,ZNF496,TNFAIP8L3,KCNJ10,MAG,ZFYVE27,BLOC1S2,PABPC1L2A,NOVA2,ZNF426,PACSIN1,PTPA,RAB5B,TRIM67,SMARCE1,FAM168A,SYPL1,USP22,NACC2,WBP2,RGMB,TMPRSS5,UBTF,TSPAN11,WRN,NAV2" MicroRNA hsa-miR-7158-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-15 1.69E-11 5.41E-15 4.98E-14 37 157 "KIAA1211,PHF12,SEMA4G,CACNB2,ABCG2,TMEM184B,PNKD,ANKRD44,PYGO1,GAPVD1,GNE,CRCP,COPS8,ATCAY,KCNN3,CREG2,PDE4D,TMOD2,BEST3,SLC36A4,PRKACB,PIGG,NCR3LG1,SEC61A2,HSPA4L,SH3BP2,NUBPL,PEX26,ANKRD36,ERC1,SSTR2,STAC2,KLHL7,SLC19A3,ZNF708,ZFAND5,GAN" MicroRNA "AAAGGAT,MIR-501:MSigDB" "AAAGGAT,MIR-501:MSigDB" MSigDB 3.03E-15 1.70E-11 5.44E-15 5.01E-14 32 118 "PCDH19,ALS2,CACHD1,SYNJ1,QKI,SLITRK5,ELAVL4,ZIC4,ATP6V1H,GRB10,HAS2,HES5,KCND2,PIK3AP1,MEF2C,NFIX,PLP1,PLXNB1,PPP2R5E,RDX,RET,ROBO2,SCN3A,SEPHS1,SOX11,NFASC,RGL1,CAMTA1,SATB2,CUX2,RPGRIP1L,SYNC" MicroRNA hsa-miR-8064:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-15 1.71E-11 5.47E-15 5.04E-14 35 141 "SLC25A25,TNRC6C,CADPS,CADM3,RAB3C,TBPL1,CRY2,IPCEF1,DNAL1,FGFR3,TRAF3IP2,PPARGC1A,GRIK3,FRMD3,BACH2,C5orf24,MBNL1,MPP2,MDGA1,NDUFA5,GTDC1,ATAT1,STX1B,SCN8A,WDR37,EMC1,UNC5B,INKA2,SYT1,NACC2,BHLHB9,TPM1,UBE2H,UBTF,MFF" MicroRNA hsa-miR-4537:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-15 1.79E-11 5.70E-15 5.25E-14 54 313 "PLEKHG5,HACE1,TXNDC16,TRMT9B,AQP6,ASPA,ATM,FOXK1,CBS,MYOM2,ADGRG1,LETMD1,TMEM170A,MTX3,WDR20,MRO,MRNIP,EPB41,EPB41L1,SCML2,CEP78,FECH,TRMO,ZNF44,NCKAP1,DISC1,CRCP,GPR75,LILRA2,KIF3A,DDX19B,DOCK7,LAMP2,CHST6,MXI1,CCSER2,MTMR10,CEP97,TRIM68,PTGR2,ATAT1,DRAXIN,SLC30A10,SCN3B,EMC1,RAP1GAP2,LHPP,PBLD,USP22,TPM3,PPIL6,SSBP2,LAT2,ZNF70" MicroRNA hsa-miR-4271:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-15 1.82E-11 5.81E-15 5.35E-14 46 236 "TRMT9B,KIF6,OGT,ARRB2,BTRC,TPP1,ZNF385A,PLEKHM1,DUSP9,APH1A,MRO,RTN3,GLUL,GPR26,CECR2,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,OLR1,PFKFB2,CDK14,PKM,FXYD1,EPB41L4B,TNPO2,WBP1L,IQSEC3,MYH14,KIAA0895L,SBF1,DRAXIN,COPZ1,SHMT2,PKNOX2,WDTC1,UNC5B,POGZ,MPRIP,AHCYL2,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-4421:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-15 1.84E-11 5.85E-15 5.39E-14 39 174 "SLC24A4,DPY19L3,CBS,FMNL3,CCNT1,ZNF445,PITPNM3,USP6NL,CENPL,TM9SF4,TMEM170A,C2CD2L,UFM1,SIGLEC8,POLL,GRIK3,HPR,ATCAY,MAP4,MEIS1,JAKMIP3,N6AMT1,SLC11A2,PALM,KLHDC8A,NCBP3,SCN2B,TRA2B,URGCP,SLC15A2,ACSBG1,FAM208A,SZT2,PCDHA6,HHIP,TPM3,ZNF708,SIGLEC10,WIPF2" MicroRNA hsa-miR-5699-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-15 1.84E-11 5.85E-15 5.39E-14 39 174 "SLC24A4,DPY19L3,CBS,FMNL3,CCNT1,ZNF445,PITPNM3,USP6NL,CENPL,TM9SF4,TMEM170A,C2CD2L,UFM1,SIGLEC8,POLL,GRIK3,HPR,ATCAY,MAP4,MEIS1,JAKMIP3,N6AMT1,SLC11A2,PALM,KLHDC8A,NCBP3,SCN2B,TRA2B,URGCP,SLC15A2,ACSBG1,FAM208A,SZT2,PCDHA6,HHIP,TPM3,ZNF708,SIGLEC10,WIPF2" MicroRNA hsa-miR-29c*:mirSVR_highEffct hsa-miR-29c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.51E-15 1.97E-11 6.29E-15 5.80E-14 30 104 "ERMN,CAPRIN2,CHN2,ABCG2,C8orf37,ENPP6,ADGRV1,GPD2,RABL2A,KCNC1,MEIS1,MYCN,ZNF862,CDK18,PPP2R5E,BDNF-AS,OCIAD1,TMEM255A,ATP8B4,CNKSR2,CCDC92,USP33,KANK1,SYNE1,MTMR14,INTS3,URM1,FIP1L1,MVB12B,CAMK1G" MicroRNA hsa-miR-219-1-3p:PITA hsa-miR-219-1-3p:PITA_TOP PITA 3.53E-15 1.99E-11 6.33E-15 5.83E-14 29 97 "ELFN2,SLITRK1,ATP2B1,JAZF1,DCLK1,NRXN3,ZNF385A,CREB5,RHOBTB1,STAG2,WASF3,RNF165,ZHX1,KCNN3,KTN1,MBNL1,LRP1B,AFF1,NF1,NFYA,CNTN3,RAB5B,HECW1,ITPRID2,SS18,ARHGEF9,SYT1,CADM1,WIPF2" MicroRNA hsa-miR-5192:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.72E-15 2.09E-11 6.65E-15 6.13E-14 34 134 "PDZD4,PPFIA4,CDC14B,BACH1,CSF1,CSNK1E,IP6K1,SPATA2,ZC3H11A,E2F6,VPS26C,FGFR1,BVES,ZFYVE27,C10orf105,NEUROD1,GPR137C,PKD1,PKM,PLCD1,NKAIN1,RAB5B,MYH14,HSD11B1L,NCBP3,MRAS,SHMT2,BTBD3,PKNOX2,IQSEC2,AHCYL2,TMPRSS5,SLC38A1,ITM2C" MicroRNA hsa-miR-6756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.26E-15 2.39E-11 7.62E-15 7.02E-14 47 247 "TAOK1,IGDCC4,BCL7A,CCNT1,ZNF445,CACNA2D2,DLGAP3,ZNF385A,CSNK1E,PHF19,IP6K1,SIRPA,PLEKHM1,ABI2,PLEKHA1,ANKRD13B,DOT1L,AHDC1,RNPS1,TNRC6A,PRRC2B,SOWAHA,KCNK3,MDFI,MPP2,ZC3H12B,NFIX,NKX2-2,NUCB1,PKM,EPN1,SPATA6,PPARA,RAB5B,CEP97,PRRT2,SETD5,KLHDC8A,ATXN2,MAGI3,UNC5B,TPCN2,TPM3,UBTF,ZNF708,SLC38A1,GAN" MicroRNA hsa-miR-1343-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-15 2.61E-11 8.31E-15 7.65E-14 41 193 "CPNE2,AP1B1,CASKIN1,ARMC12,ARRB1,ASPH,DIRAS1,CBS,TMEM184B,RGS6,PHYHIP,PLEKHM1,ABCC5,ING4,AMOTL2,HBS1L,SRCAP,TNFAIP8L3,HMX1,SHISA6,SOWAHA,KIF5A,MSI1,NBL1,GPR173,PTPA,C12orf49,RPS6KA2,CLSTN1,LHFPL4,ERC1,NFASC,CLSTN2,CAMTA2,SEPT8,FAM168A,SLC19A3,CBX5,RPRM,UBTF,HNRNPA3" MicroRNA hsa-miR-6887-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-15 2.65E-11 8.45E-15 7.78E-14 34 135 "HACE1,TRMT9B,PRX,ARHGDIA,BCL7A,CALM1,NEURL1,DLGAP3,ZNF385A,PYGO1,PHYHIP,ERBB2,MTHFD2,GCK,GFER,NXPH3,NRGN,BEST3,PLEC,ZNF426,SDK2,NCR3LG1,BDNF-AS,PRRT2,HSD11B1L,SMTN,SON,NMNAT2,NFASC,USP22,RBFOX2,TUBB2A,RPRM,MGAT5B" MicroRNA hsa-miR-544a:Functional MTI Functional MTI miRTarbase 4.82E-15 2.71E-11 8.61E-15 7.93E-14 36 151 "WDR35,CC2D2A,SPOP,SLC7A14,STX16,CAPN3,DLGAP2,ADGRG1,CLTC,DCAF8,TMEM170A,DCC,EPB41,MTSS1L,NCKAP1,GOLGB1,NR3C1,ATOH8,GPR45,PPM1L,NEUROD1,GPR137C,PDGFRA,DUSP26,PIK3C2A,RFX3,FNDC3A,SMARCE1,STXBP1,ASTN2,SYT5,PCDHAC2,FBXL16,TMOD1,SF1,INTS3" MicroRNA hsa-miR-296-5p:mirSVR_highEffct hsa-miR-296-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.83E-15 2.71E-11 8.63E-15 7.95E-14 44 220 "PTCHD1,LRFN1,CDC14B,CCAR2,BCL2L2,CACNG1,P2RX6,KCNAB3,NUMBL,SYNPR,CNTFR,SUMF2,SMG7,NYAP1,PHC2,RBM12,YAF2,CELSR3,TAOK3,TOMM40L,KAT8,MAD2L2,TMEM151A,TXNL4A,RAB30,MAP7D2,PSIP1,HMGCL,KCNQ2,PCSK5,GPR173,ZDHHC8,EPN1,PPP1R1A,NTNG1,SHC4,CDK5RAP3,SPHKAP,SOX10,LMO3,OBSL1,AKNA,SLC26A10,PLPPR5" MicroRNA hsa-miR-412-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.85E-15 2.73E-11 8.67E-15 7.99E-14 35 143 "OSBPL8,DGKD,CDH2,STOML1,PNKD,SUSD5,DOCK4,GAPVD1,CENPL,CALN1,NR1D2,EEF1A2,STARD3NL,SRARP,DLC1,CELF1,DOT1L,GUCY1A1,KPNA5,SYTL4,TMOD2,PKD1,MYH14,SCN8A,CPEB4,SON,ZC3H13,CYB561A3,CDH22,TMOD1,ZNF138,ZNF195,INTS3,CSDE1,TUBA1A" MicroRNA "AATGGAG,MIR-136:MSigDB" "AATGGAG,MIR-136:MSigDB" MSigDB 5.53E-15 3.11E-11 9.88E-15 9.10E-14 25 72 "SORCS1,USP37,JAZF1,KALRN,PLCXD3,CPEB2,DYRK1A,SGIP1,PPARGC1A,GNG3,GRID1,ICA1,KCND1,SYTL4,NPR2,SNRK,PTPRG,RAD51D,RGS4,PBRM1,RADIL,KDM3A,SEPT3,RPGRIP1L,ZIC3" MicroRNA hsa-miR-1908:mirSVR_highEffct hsa-miR-1908:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.74E-15 3.23E-11 1.03E-14 9.44E-14 37 160 "ADAR,PPFIA1,SUGT1P4-STRA6LP-CCDC180,SPTBN4,STK33,KALRN,NRXN3,SUMF2,PLCH2,CCDC144A,SMG7,DYRK1A,ELN,EPB41L1,SEZ6,GTF2IRD2,MAD2L2,AKAP3,TVP23A,SIGLEC8,C15orf41,C1QL1,GLDC,LOXL3,OPALIN,MIA2,PABPC1L2A,PEX26,SIRT2,SMARCD3,ANO4,PRRT1,PIK3R5,PPIL6,PDIA2,SLC17A7,WNK3" MicroRNA hsa-miR-361-5p:Functional MTI Functional MTI miRTarbase 5.74E-15 3.23E-11 1.03E-14 9.44E-14 37 160 "RALGAPA1,ACLY,ZBTB10,BACH1,VXN,KIAA1549L,FGFR1OP2,DCTN1,COPS7A,G3BP2,ABI2,JKAMP,MSANTD4,ZMYND11,TNRC6A,HSF2,HSP90AA1,KCNJ3,MDM4,AFF1,ZNF92,OGDH,PDE3A,PLCL1,SEMA6D,HSPA4L,SGK1,SON,LHFPL4,USP22,ZMAT3,TP53BP1,WBP2,MTCH1,ZNF154,TFIP11,WIPF2" MicroRNA hsa-miR-136-5p:Functional MTI Functional MTI miRTarbase 5.74E-15 3.23E-11 1.03E-14 9.44E-14 37 160 "ADCYAP1R1,GPR158,MADD,EIF4G3,DST,CACNA1D,NIPBL,BTF3L4,NRG2,C2CD2,SEC14L5,GAPVD1,TMEM170A,G3BP2,FSD1L,ABI2,SLC37A3,STAG2,GABRG2,DISC1,GNAS,PCLO,RABL2A,IFI16,ATXN1,FNIP1,NUBPL,FAM214B,SNAP25,ZNF621,ITPRID2,GANAB,ABCC8,DDHD1,RBFOX2,RPL7L1,SLC38A1" MicroRNA hsa-miR-5590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-15 3.26E-11 1.04E-14 9.54E-14 43 212 "CC2D2A,SEMA7A,CAPRIN2,CALM1,SLC24A2,RIMS4,UBXN2A,FAM107B,CERCAM,RCAN2,DLC1,FOXO3,C15orf41,LUZP2,FUT10,KIF3A,MAT2A,MKLN1,PDE4D,PFKP,ZFYVE21,PDZRN4,PRKCB,SLC22A23,PEX2,CEP97,FIGN,ALG9,ROBO1,ACER3,ATXN1,FAM126B,SON,ZBTB43,SMOC1,ANKRD28,TNS1,RGMB,SMUG1,UBE2H,ZNF711,SLC38A1,STOX2" MicroRNA hsa-miR-6506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.84E-15 3.28E-11 1.04E-14 9.59E-14 61 390 "ZNF578,TAOK1,KIF6,MTMR9,BCL2L2,LDHD,AP1M1,FOXK1,PLAA,COL9A2,CRY2,RGS6,CSNK1E,PPP1R16B,UBXN2A,DNAL1,RABGAP1L,SLC12A6,ABI2,IRAK4,MRPL37,VPS26C,TLR7,GTF2IRD2,FOXO3,TRAF3IP2,MTHFD2,KIAA1841,TXNL4A,CRCP,POLL,KIF3A,BVES,MFSD2A,HMGB1,ZDHHC15,NEGR1,ATCAY,KCND3,CYP27C1,GPR155,MBD1,OCIAD1,C12orf49,FOXRED2,HSPA4L,PEX26,SP2,EMC1,AJAP1,ACSBG1,WWC1,GPRIN3,ZMAT3,CBX5,PARD3,RPL7L1,WRN,ZNF708,ZBTB38,MPPE1" MicroRNA hsa-miR-4716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.96E-15 3.35E-11 1.06E-14 9.79E-14 39 177 "TRMT9B,ATP1A2,SEPT7,AKAP6,BTF3L4,CSNK1E,KIAA0408,FGFR1OP2,KIAA0586,DBN1,CPEB2,GNE,DYRK1A,WDPCP,SRARP,TRMO,CELF1,ZNF274,CYP27C1,ADAM22,MYO6,TMOD2,PTAFR,UEVLD,NUBPL,PEX26,FAM126B,CLUAP1,KIF1B,ZNF621,SSTR2,ZFR2,ALG1,AGTPBP1,SGK3,ZNF70,SLC38A1,MSRB3,GAN" MicroRNA hsa-miR-6795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-15 3.37E-11 1.07E-14 9.84E-14 34 136 "HACE1,TRMT9B,PRX,ARHGDIA,BCL7A,CALM1,NEURL1,DLGAP3,ZNF385A,PYGO1,PHYHIP,ERBB2,MTHFD2,GCK,GFER,NXPH3,NRGN,BEST3,PLEC,ZNF426,SDK2,NCR3LG1,BDNF-AS,PRRT2,HSD11B1L,SMTN,SON,NMNAT2,NFASC,USP22,RBFOX2,TUBB2A,RPRM,MGAT5B" MicroRNA hsa-miR-191-5p:TargetScan hsa-miR-191-5p TargetScan 6.24E-15 3.50E-11 1.11E-14 1.02E-13 20 44 "PITPNM2,CASK,ATP2B2,PITPNM3,LIN54,CALN1,PHC2,EMX2,NEURL4,GAP43,GLYR1,NFIA,NRCAM,PLCD1,RFX3,SATB1,AJAP1,SATB2,LRRC8A,JPH3" MicroRNA "ATAGGAA,MIR-202:MSigDB" "ATAGGAA,MIR-202:MSigDB" MSigDB 6.43E-15 3.61E-11 1.15E-14 1.05E-13 29 99 "ACTN1,SORCS1,CNN3,BAG4,KIAA0408,SNAP91,YAF2,PLEKHA1,SUCO,MEX3B,KLF12,HLF,LDLRAD3,MED1,PPP5C,TTC13,RAD52,KHDRBS2,ROBO2,ATXN1,SCN2B,SFPQ,CPEB3,CCDC88A,ERBIN,TCF12,SSBP2,STOX2,VANGL2" MicroRNA hsa-miR-516a-5p:mirSVR_highEffct hsa-miR-516a-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.43E-15 3.61E-11 1.15E-14 1.05E-13 40 186 "XKR4,RGS9,ST3GAL5,WHRN,CPS1,VCAN,DDX46,OLIG1,SRRM1,STAU2,BRPF3,SALL3,CRCP,GRIA2,FAM222A,ELOVL5,AGBL5,LRP1B,SRSF12,STK32C,MXI1,MYBPC1,NTRK3,EXOSC10,DCHS2,PTPRE,ZSCAN2,ARID4A,FEZF2,FIGN,ARMH4,EFHD1,SNCB,KIF1B,FAM200B,ASXL3,SEZ6L,METTL3,PRMT8,TSC1" MicroRNA hsa-miR-6783-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.43E-15 3.61E-11 1.15E-14 1.05E-13 40 186 "ELFN2,TRMT9B,KIF6,PPFIA3,ARRB2,CBS,METTL6,ZNF385A,SIRPA,TMCC2,HEYL,APH1A,MRO,IRAK4,RTN3,ZNF496,DDX19B,KCND1,ZFYVE27,MAT2A,JAKMIP3,OGG1,OLR1,PDE4D,CDK14,EPB41L4B,TNPO2,TMEM145,RAB3A,HKR1,PKNOX2,COA1,ZNF423,SPART,TAB2,MPRIP,ASXL3,TNS1,UBTF,BCL2L13" MicroRNA hsa-miR-607:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.57E-15 3.69E-11 1.17E-14 1.08E-13 45 231 "CACNA1A,CREB5,TMEM170A,YTHDC1,ANKRD46,TMTC1,YAF2,ELAVL4,ZNF549,SCML2,IQCG,PDLIM5,WASF3,TCERG1,TNRC6A,NUDT21,CIT,NACA,NASP,KSR2,PDE3A,FAM98B,SH3KBP1,PPARA,RAD52,SH3TC2,BSDC1,SALL1,CSRNP3,FAM19A1,ATF7IP,CPEB4,IGSF9B,FAM126B,CLUAP1,PEG10,PRRC2C,FAM208A,LRRC8A,FNDC5,RPL7L1,VLDLR,ZNF225,SLC38A1,PRDM10" MicroRNA hsa-miR-1253:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.75E-15 3.79E-11 1.20E-14 1.11E-13 41 195 "SEMA7A,ARMC12,BTK,CANX,CDC27,ZNF445,ARHGEF6,LETMD1,AKAP5,RNF14,KIAA0040,KIAA0513,CHRDL1,SLC43A2,SRARP,MRVI1,FAM49B,TRAF3IP2,CECR2,GRB10,LRRC75A,KCNH2,SYT9,GPR173,TNPO2,PTPA,FIGN,SLC25A36,SETD5,ARMH4,KCNIP2,FOXRED2,BTBD3,ASTN2,RBFOX2,TPD52L2,TUBB2A,RPRM,URM1,ITM2C,WIPF2" MicroRNA hsa-miR-4257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.09E-15 3.98E-11 1.26E-14 1.16E-13 60 381 "ABCF1,NDRG3,PLEKHG5,HECW2,CARNS1,TRMT9B,ATP1B3,MTMR3,FOXK1,DDR1,DIRAS1,FMNL3,CBFA2T2,MYOM2,CCPG1,EPS15L1,NRXN3,POM121,ST8SIA3,ANKRD46,RASA4,MRNIP,SLC43A2,ANKMY1,KATNAL1,TUBB4A,TMEM151A,MTHFD2,GATM,CSDC2,CRCP,GNG4,KIF3A,KAT7,DDX19B,SCRG1,HSP90AA1,ZNF546,IBA57,KCNH1,NAT8L,CCDC80,NUCB1,TMOD2,PLEC,ALG9,GSTCD,GALNT10,FAM102A,MYO18A,MAGI3,SLC8A3,ATF7IP,SCN3B,NEK4,ACSBG1,NACC2,BHLHB9,TPM3,ZNF70" MicroRNA "GGCACAT,MIR-455:MSigDB" "GGCACAT,MIR-455:MSigDB" MSigDB 7.46E-15 4.19E-11 1.33E-14 1.22E-13 22 55 "ADD3,RTL9,SEMA4G,CDK13,DCAF5,CACNB4,RIMS4,SLITRK5,PLCXD3,USP3,EDN1,GABRB3,HES5,CDK14,RFX4,STX1B,SOX6,SPHKAP,SOX11,DOCK9,TJP1,ZIC3" MicroRNA hsa-miR-3916:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.78E-15 4.37E-11 1.38E-14 1.27E-13 40 187 "CPNE2,CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,BTF3L4,CTNND1,PYGO1,PHF19,IP6K1,DBN1,PLEKHM1,DNM2,AMOTL2,AFF2,CELF1,GAP43,CECR2,HSP90AA1,IDH3A,MID1,CCDC80,PABPC1L2A,DDR2,FIGN,ELP2,PRR5L,TRIM67,COA1,SON,DIP2A,SATB2,HIF3A,ZFP91,TUBB2A,WRN,ITM2C,WIPF2,C12orf4" MicroRNA hsa-miR-196a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.27E-15 4.64E-11 1.47E-14 1.35E-13 42 205 "ARID1A,XKR4,SLC24A4,HACE1,ARSE,ATP1B3,MTMR3,SUSD5,UBXN2A,GAPVD1,CENPL,MTX3,EIF4G2,EPB41,ZNF549,ZNF234,ATP8A2,CRCP,GPR75,NR3C1,LINGO1,DDX19B,DOCK7,SLC11A2,OLR1,TATDN3,PEX2,ZNF844,KLHL11,KLHDC8A,SEC31A,KANSL3,SLC11A1,SMARCE1,EMC1,IQSEC2,ADAMTS17,AHCYL2,RPL7L1,TBC1D15,TRIM16L,TIGD6" MicroRNA hsa-miR-498:Functional MTI Functional MTI miRTarbase 8.28E-15 4.65E-11 1.47E-14 1.35E-13 54 320 "AS3MT,RNF157,SLC7A14,KIAA1614,SLC4A4,ATP2B1,NRXN1,CSNK1E,PLXNA4,CNNM1,MRNIP,RGS17,EPB41L1,ERBB2,FDFT1,FOXO3,SLC37A3,NCKAP1,FAXC,CRCP,CNDP1,RNF165,ZNF491,NKD1,ITPKB,NCOA7,GPR155,MATN3,MID1,MOG,SAMD5,PCSK1,FAM216A,FITM2,ZNF844,NWD1,GALNT10,SFPQ,FNDC3A,PEX26,ZNF667,CLUAP1,EPB41L3,WWC1,PCDHA6,DICER1,ZNF106,ASXL3,RBFOX2,UBE2H,AGMO,ZXDA,LMAN2L,WIPF2" MicroRNA hsa-miR-635:PITA hsa-miR-635:PITA_TOP PITA 8.62E-15 4.84E-11 1.53E-14 1.41E-13 29 100 "GPRIN1,PPFIA3,DCAF5,RCBTB2,FOXN3,QKI,PCYT1B,ZNF385A,FAM131B,KLHL3,DLG2,DLG4,APH1A,RRAGB,FOXG1,BRSK1,ATF7,PIK3R1,PPP3CA,PROX1,FAM120C,SGSM1,RTN1,SOX11,PEG10,NKAIN2,VAMP1,SYT1,MAP3K12" MicroRNA hsa-miR-521:mirSVR_highEffct hsa-miR-521:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.84E-15 4.96E-11 1.57E-14 1.44E-13 39 179 "KDM5D,PDE8B,ZSCAN18,DST,TPP1,PREPL,PDE4DIP,NOS1AP,KIAA0753,EBF1,PLEKHA1,ARMCX1,TMEM107,DOT1L,OGA,GALNT15,NEU3,ARFIP1,TNRC6A,PCDH11X,GPD2,GRIA4,GRIK2,FAM222A,HLF,KCNMA1,MYT1,NELL1,NF1,OTOGL,RGR,FAM19A1,MAST1,SORCS3,CLASP2,FNDC9,TCF7L2,CSMD1,NETO1" MicroRNA hsa-miR-151-5p:mirSVR_highEffct hsa-miR-151-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.24E-15 5.19E-11 1.64E-14 1.51E-13 33 130 "RALGAPA1,CDC7,KIDINS220,SLC44A5,FAM131A,CACHD1,NRP2,CACNA1G,KALRN,PTBP2,LGI1,SYNPR,IST1,APH1A,ELAVL3,RGS17,EPHB1,SRRM1,ERAP1,ZNF638,NME9,KCNJ10,KCNK1,MEST,PCMT1,VSTM2L,PRODH,RASGRF2,RNF220,SNAP25,DNMBP,SEZ6L,CCDC14" MicroRNA hsa-miR-4433a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.68E-15 5.44E-11 1.72E-14 1.58E-13 59 373 "SLC24A4,TXNDC16,SMIM17,AMH,APAF1,PDXK,ZNF583,BTRC,ISPD,MYOM2,NDST3,NRXN3,CS,SUSD5,CTH,USP6NL,GAPVD1,KIAA0513,RASSF2,LONRF1,TMEM170A,ELMSAN1,ZNF549,ZNF585B,FAM120B,MTHFD2,GPR75,GLUL,LUZP2,GNAS,LILRA2,ZBTB49,KCNJ5,STMN1,CHST6,PPM1L,MMP17,MPP2,SFR1,NUCB1,ZNF713,PIK3CD,CCSER2,PLEC,PACSIN1,MTMR10,ZNF844,CEP97,MSANTD2,SEMA6D,PREX2,SLC2A5,NEK4,MGRN1,PSD3,AHCYL2,SSBP2,ZNF610,ZFAND5" MicroRNA hsa-miR-500b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.88E-15 5.55E-11 1.75E-14 1.61E-13 42 206 "ADCY2,ARMC12,BARD1,ZBED1,RTTN,PYGO1,DBT,OPTN,C3orf18,FGF1,MSANTD4,GPR75,KAT7,SLC2A6,DDX19B,ZNF491,HNRNPK,CCDC80,NOVA2,PCSK2,TMOD2,ZDHHC8,KCTD15,GPSM2,STRN3,PIGG,PTCH1,MTMR10,ZYG11B,PGBD4,HSPA4L,IGSF9B,ERC1,SMOC1,KLHL7,KIAA0930,ZNF34,WRN,ZNF74,MVB12B,TIGD6,AP3B2" MicroRNA hsa-miR-1252-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-14 6.05E-11 1.91E-14 1.76E-13 37 163 "TRMT9B,PDXK,BCL7A,FOXK1,CANX,CNGA3,CRY2,LONRF1,CHRDL1,PHC2,EIF1,PRRC2B,TNFAIP8L3,MAN2A2,ZFYVE27,SYT9,MKLN1,CCDC80,MYCN,NUMA1,ZNF827,SNX10,UHRF1BP1,FIGN,UBR7,SETD5,SGK1,LGI3,IQSEC2,MPRIP,TAF6,HIF3A,WBP2,WRN,XKR7,ITM2C,SPATA13" MicroRNA hsa-miR-210-3p:Functional MTI Functional MTI miRTarbase 1.10E-14 6.17E-11 1.95E-14 1.79E-13 32 123 "APC,CDK10,BTK,THSD7A,RUNX1T1,FOXN3,HECTD1,NIPBL,CSNK1E,GIT2,CPEB2,CASP8AP2,EFNA3,TBC1D16,AIFM3,CBX1,HSD17B1,DOCK7,KCNB1,STMN1,MITF,MDGA1,NCAM1,NPTX1,KCNK10,PKIA,RAD52,GTDC1,CHD9,CLASP2,MGRN1,HIF3A" MicroRNA "TCTGATA,MIR-361:MSigDB" "TCTGATA,MIR-361:MSigDB" MSigDB 1.11E-14 6.24E-11 1.97E-14 1.81E-13 27 87 "ADCY2,ADD3,DPP10,CAMK2D,MAGI1,QKI,ARMC8,CTNND2,NTM,CALCRL,GPHN,RRAGB,AFF2,LRP1B,MXI1,PCDH9,PDE4B,ZNF655,PLP1,PEX5,LGR4,SCAF8,SLC1A3,SON,STAU1,ZFPM2,WNT7A" MicroRNA hsa-miR-384:Non-Functional MTI Non-Functional MTI miRTarbase 1.15E-14 6.46E-11 2.04E-14 1.88E-13 29 101 "ADD2,GAS7,ATP1A1,RUNX1T1,LONRF2,CNN3,CREB5,EN2,COQ7,CDHR1,MRVI1,SRRM4,FREM1,GPR155,SESN3,NFIX,NTRK3,KANSL1,MARCH1,FBXW7,SCN2B,ZFP30,ST6GAL1,TCF7L2,ZNF34,C5orf64,TRPS1,RICTOR,WNK1" MicroRNA hsa-miR-497-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-14 6.46E-11 2.04E-14 1.88E-13 29 101 "ADARB2,BACH1,FOXK1,CDC27,ABCG2,PITPNC1,DPP6,MAMLD1,TMTC1,EFNA3,KIAA1109,GABRB3,PRRC2B,HSP90AA1,SHISAL1,DIPK1A,THYN1,OPHN1,MAPK8,NWD1,ELP2,TMEM200C,TRA2B,SLC1A2,NFASC,GANAB,SLC30A3,SLC30A4,NETO1" MicroRNA "AAACCAC,MIR-140:MSigDB" "AAACCAC,MIR-140:MSigDB" MSigDB 1.15E-14 6.46E-11 2.04E-14 1.88E-13 29 101 "GALNT16,ZNF608,OGT,ANK2,API5,ZBTB10,DDX3Y,BACH1,BCL2L2,SYT6,USP6,CSNK1G3,HDAC4,PHYHIP,DSCAM,PHF20L1,EPHB1,LOXL3,NR3C1,CIT,KCND2,TTYH2,GIT1,PDGFRA,MDGA2,PRIMA1,LRRC4,R3HDM1,NAV3" MicroRNA hsa-miR-4473:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-14 6.57E-11 2.07E-14 1.91E-13 22 56 "RNF157,ADD1,OSBPL8,CAPRIN2,PRC1,CLCN3,CEP170,FEM1B,FLT1,MALT1,IL6ST,KCNB1,PURG,LRP12,UEVLD,CLIP1,SPART,ZMAT3,THRA,TPD52,ZNF154,WIPF2" MicroRNA "ATAACCT,MIR-154:MSigDB" "ATAACCT,MIR-154:MSigDB" MSigDB 1.17E-14 6.57E-11 2.07E-14 1.91E-13 22 56 "MTUS1,OSBPL8,OGT,ATP2B1,CAMK2G,FOXN3,SOCS5,FGFR1OP2,DYRK1A,E2F5,WAC,GRM7,KAT7,MAP4,CNOT4,RAB5B,SALL1,PPM1E,PKNOX2,TCF12,FBXL16,EVI5" MicroRNA hsa-miR-220b:PITA hsa-miR-220b:PITA_TOP PITA 1.20E-14 6.72E-11 2.11E-14 1.95E-13 35 147 "RBM10,ATP2B1,CAMK2G,LRBA,DCLK1,CTNND1,EGR3,TENM1,CHL1,RND1,KDM2B,CECR2,KCNA1,KCND2,MARK1,GIT1,PABPC1L2A,NKX2-2,PDE4B,ANKRD16,PPP3CA,PKIA,C1orf109,CYB561D1,PPM1E,WDR47,MYO16,SOX11,ERBIN,ZC3H4,CLASP1,DOCK9,UBE3A,ZIC3,FXR1" MicroRNA hsa-miR-181a*:mirSVR_highEffct hsa-miR-181a*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-14 6.72E-11 2.11E-14 1.95E-13 35 147 "OSBPL8,TNRC6C,APP,MIER1,ATM,CACNB2,CALB2,THSD7A,LOC730101,MAGI1,CFL2,KIF26A,ARMCX4,RHOBTB1,ATP13A4,MYOZ2,GLS,GPD1,HMGCL,KCNK2,KCNN2,RTL5,PRKCZ,GRAMD1C,RGS3,ROBO1,ABCA11P,SCN2A,SCN8A,SLC20A2,SMARCE1,KIF13A,TRERF1,TNR,SMUG1" MicroRNA "GACAGGG,MIR-339:MSigDB" "GACAGGG,MIR-339:MSigDB" MSigDB 1.28E-14 7.17E-11 2.26E-14 2.08E-13 23 62 "HAP1,NRXN1,PPP6R2,CTIF,C3orf18,EMX2,FHL1,FLT1,ABLIM2,GRM3,ATXN2L,HNRNPK,KCNMA1,NNAT,NOVA1,CDK14,CDIP1,NXPH1,NFASC,THRA,TRPC3,UBE3A,SLC4A10" MicroRNA hsa-miR-3133:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-14 7.68E-11 2.42E-14 2.23E-13 40 190 "TTYH1,SDE2,TMCC3,CC2D2A,TAOK1,TRMT9B,KIF6,ATM,ATP2A2,LDHD,FAM169A,RIMS3,MFAP3L,BLOC1S6,RCAN1,ABCC9,FRY,GJB1,GPR26,HAS2,HSP90AA1,ZIC5,RBPJ,LAMA2,MAT2A,NEXMIF,KCTD15,ZNF426,FIGN,RGR,ACER3,MYO16,SON,BDP1,SEPT8,SLC44A1,RBFOX2,SEZ6L,SF1,RNF146" MicroRNA hsa-miR-4701-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-14 7.81E-11 2.46E-14 2.26E-13 46 245 "TAOK1,GOLGA7B,KIF6,C6orf89,SLC7A14,PDXK,ATP1A2,RAB3C,AKAP6,LRIG1,CSNK1E,MYADM,FGFR1OP2,KIAA0586,BLOC1S6,RABGAP1L,SIDT2,COQ7,CEP78,TRMO,CRCP,COPS8,IL1RAPL1,SLC2A6,DDX19B,ATCAY,ZNF678,CYP27C1,MYO6,FBXW7,SGSM1,PTGR2,SATB1,PEX26,FAM126B,KIF21B,CLUAP1,KIF1B,LHPP,ALG1,WWC1,AGTPBP1,ZNF70,URM1,AP3B2,GAN" MicroRNA hsa-miR-3140-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-14 7.91E-11 2.49E-14 2.29E-13 32 124 "AS3MT,MTUS1,PCDH19,ARRB1,CCDC74A,IGDCC3,LRIG1,GPRASP1,MRO,ERBB2,FOXF2,HBS1L,SRCAP,PCDH17,PRRC2B,GRIK3,MIER3,RBPJ,MKLN1,NPTX1,MTRF1L,ZSCAN2,ZDHHC14,C12orf49,ROBO1,PEX26,LIMCH1,SON,RBM26,ZMYND8,FNDC5,ZNF711" MicroRNA hsa-miR-4776-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-14 7.98E-11 2.51E-14 2.31E-13 30 109 "SERPINA3,ADD3,KIF6,MARCH3,NOL4,CD38,BAG4,PITPNM3,CTNND1,DBN1,EBF1,BRPF3,ZNF274,GPR26,ZNF546,NTRK3,PDE3A,GDPD1,NWD1,RNASEL,SALL1,SCP2,SNAP25,TRPS1,VLDLR,ZNF28,ZNF138,PRDM10,PAK5,FXR1" MicroRNA hsa-miR-548as-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-14 8.24E-11 2.59E-14 2.38E-13 38 173 "XKR4,SLC24A4,TNRC6C,NRXN1,ZNF385A,ATRNL1,CTH,E2F6,AFF2,BRPF3,NCKAP1,MTHFD2,PRRC2B,NUDT21,CACFD1,MIER3,NEGR1,ITPKB,JAK2,MAT2A,MDM4,SAMD5,CTNNA3,NDUFA5,ARID4A,ROBO1,PCMTD2,BCAN,SLC1A2,ATF7IP,SON,SOX3,NPAS3,AJAP1,CLASP1,SF1,CADM2,WNK3" MicroRNA "GAGCCTG,MIR-484:MSigDB" "GAGCCTG,MIR-484:MSigDB" MSigDB 1.53E-14 8.59E-11 2.70E-14 2.48E-13 29 102 "PCDH19,SEMA4G,GAPVD1,DPYSL2,PHC2,FAM13A,EZH1,FGF1,SCARA3,GRB10,KLF12,ZIC5,NFIA,RETREG1,CEP41,PRKCB,PTPRE,ZYG11B,PRRT2,GTDC1,YJEFN3,SLC6A1,ZNF667,MYCBP2,KIAA0930,TRPS1,PLEKHH2,NSD2,ZIC1" MicroRNA hsa-miR-106b*:mirSVR_highEffct hsa-miR-106b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.53E-14 8.59E-11 2.70E-14 2.48E-13 29 102 "SYNJ2,FHL5,OSBPL3,CFAP61,FBXL5,IQCG,JKAMP,DOT1L,COPS8,TNRC6A,GRIA4,AP4S1,RNFT2,INSYN2,ZNF827,FAM218A,FEZF2,FAM19A1,SH3GL3,AJAP1,PRRC2C,TCF4,SLC44A1,TIAM1,ZMYND8,PLPP4,STOX2,TMEM178A,TRAM2-AS1" MicroRNA hsa-miR-8084:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-14 8.83E-11 2.77E-14 2.55E-13 28 95 "CDC14B,STX16,NIPA1,QKI,BAG4,ABI2,C8orf37,ACSL4,CELF1,SALL3,SESN1,FERMT2,NUDT21,HMGB1,MYBPC1,OPHN1,GPR137C,PKD1,MAPK7,GDPD1,ZFHX4,ROBO2,MBD5,ZNF621,CAMSAP2,PSD3,ZMAT3,TUBB2A" MicroRNA hsa-miR-6859-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-14 8.85E-11 2.78E-14 2.56E-13 39 182 "CPNE2,CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,BTF3L4,PYGO1,PHF19,IP6K1,DBN1,PLEKHM1,DNM2,AMOTL2,AFF2,CELF1,GAP43,CECR2,HSP90AA1,IDH3A,MID1,CCDC80,PABPC1L2A,DDR2,FIGN,ELP2,PRR5L,TRIM67,COA1,SON,DIP2A,SATB2,HIF3A,ZFP91,TUBB2A,WRN,ITM2C,WIPF2,C12orf4" MicroRNA hsa-miR-298:Functional MTI Functional MTI miRTarbase 1.62E-14 9.11E-11 2.86E-14 2.63E-13 37 165 "XKR4,ADD1,ESYT2,AK2,PHF12,APP,MIER1,ARHGDIA,ZBTB10,ST3GAL5,HAP1,AKAP5,DNAL1,DCC,G3BP2,DYRK1A,ENPP6,ZNF589,GABRB3,SRRM4,GLUL,GRB10,RNF165,COMMD5,PDGFRA,CCSER2,QDPR,PLEKHB2,SLC8A3,WDTC1,TMEM178B,NSD1,TMPRSS5,UBTF,USP1,ZNF138,CSDE1" MicroRNA hsa-miR-4435:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-14 9.14E-11 2.86E-14 2.64E-13 46 246 "GOLGA7B,C6orf89,APAF1,PDXK,ARHGDIA,ATP1A2,RAB3C,AKAP6,LRIG1,CSNK1E,SOCS5,MYADM,KIAA0513,KIAA0586,DBT,BLOC1S6,RABGAP1L,SIDT2,COQ7,TRMO,CRCP,DDX19B,ATCAY,ZNF678,CYP27C1,MPP2,MYO6,MINDY2,ZNF793,SGSM1,PTGR2,PEX26,FAM126B,UNC5B,KIF1B,LHPP,SSTR2,DIP2A,ALG1,WWC1,AGTPBP1,TCF7L2,WBP2,ZNF384,ZNF70,GAN" MicroRNA hsa-miR-216b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-14 9.23E-11 2.89E-14 2.67E-13 31 117 "ABCF1,ANK3,TNRC6C,ATP2A2,JAZF1,CDH2,CRY2,IPCEF1,CENPL,MED24,SACS,SNX29,HSPA12B,HRASLS5,SEPT9,KIF5C,MXI1,NEXMIF,ZDHHC22,MTRF1L,ZYG11B,ATAT1,DRAXIN,GALNT10,EMC1,GALNT17,ZNF610,UBE2H,UBTF,ZNF781,DHX33" MicroRNA hsa-miR-3190-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.67E-14 9.39E-11 2.94E-14 2.71E-13 50 285 "KIAA1324,APAF1,GPAM,CBS,CCNT1,CTH,GREB1,KIAA0513,DBT,YTHDC1,MRO,ABI2,ZNF549,GLUL,LUZP2,FICD,MAG,SAMD5,PABPC1L2A,SFR1,SLC11A2,OPHN1,TNPO2,MINDY2,PTPA,MAPK8,PTPRB,ZNF793,SNX22,RTKN,FOXRED2,HOGA1,MAGI3,SLC1A2,URGCP,PREX2,UNC5B,NEK4,SYT11,TCF7L2,USP22,ZMAT3,TPM3,ZNF384,ZNF610,TBC1D15,ZNF708,ZNF70,RGMA,URM1" MicroRNA hsa-miR-1909*:mirSVR_highEffct hsa-miR-1909*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.69E-14 9.47E-11 2.97E-14 2.73E-13 51 295 "SDE2,NCKAP5,SMIM17,ZNF687,APC,MMD2,CA4,KALRN,CDO1,RCBTB2,CASC2,SRP14-AS1,SLITRK5,USP6NL,HDAC9,BRINP1,ABI1,DCTN4,GMPR2,C2orf88,CAB39,RAPGEF6,KIAA1841,RAB30,GLS,WDFY3-AS2,PTGDR2,LRRC75A,MATN2,MEF2C,ERICH3,ADAM22,FSD1,SAMD9,ATG16L1,CCDC82,SEMA6D,PEAR1,NTNG1,CNKSR2,NUBPL,DHX30,CDK5RAP3,CAND2,ATP10B,SYNE2,ARHGEF9,ADGRL3,TCF12,DICER1,LRRC8A" MicroRNA hsa-miR-663:mirSVR_highEffct hsa-miR-663:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-14 9.86E-11 3.09E-14 2.84E-13 36 157 "ADAR,PPFIA1,SUGT1P4-STRA6LP-CCDC180,SPTBN4,STK33,MMD2,KALRN,NRXN3,SUMF2,PLCH2,CCDC144A,DYRK1A,ELN,EPB41L1,SEZ6,GTF2IRD2,MAD2L2,AKAP3,TVP23A,SIGLEC8,C1QL1,LOXL3,MIA2,PABPC1L2A,FEZF2,PEX26,SIRT2,SMARCD3,ANO4,PRRT1,PIK3R5,PPIL6,PDIA2,PLPPR2,SLC17A7,WNK3" MicroRNA hsa-miR-4267:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-14 9.86E-11 3.09E-14 2.84E-13 36 157 "NCKAP5,SLC25A25,ZNF578,ABCD2,SEMA7A,GYG2,CBS,LRRFIP1,NDST3,ARHGAP22,PLXNA4,ELMO1,ABI2,EPB41,PDLIM5,RAPGEF6,PARD3B,SLC6A17,ZFYVE27,CCSER2,MTRF1L,ALG9,FAIM2,INKA2,APOM,KIAA0930,CYB561A3,LEFTY2,CBX5,TMPRSS5,CLDND1,XKR7,SNX27,WIPF2,WNK2,RNF146" MicroRNA hsa-miR-1282:mirSVR_highEffct hsa-miR-1282:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.76E-14 9.86E-11 3.09E-14 2.84E-13 36 157 "INTS2,C1QTNF3,TNRC6C,TMEM263,ARHGEF7,CACNA1G,CA4,AKAP5,ARHGAP32,MAML1,COQ7,RCAN2,LRRC17,EYA1,FGF14,SMC2,ZNF385B,MSRA,MYBPC1,NF1,JAKMIP1,PLIN1,RASGRF2,NEK11,PEAR1,CHD9,SLC2A5,SNRPN,SOX2,KDM4C,UNC5B,ASTN2,HIF3A,ITGB3BP,TMPO,FMN2" MicroRNA "GGGGCCC,MIR-296:MSigDB" "GGGGCCC,MIR-296:MSigDB" MSigDB 1.84E-14 1.03E-10 3.23E-14 2.98E-13 24 69 "UNC5A,PPFIA3,ARRB1,GPC2,TRIM41,LARGE1,NOG,NUMBL,CNTFR,CTIF,DBN1,TAOK3,CPLX2,PTPN5,SOX21,EPN1,KCTD17,SOX10,SOX11,IQSEC2,TRPM2,PLPPR5,SLC30A3,PARP6" MicroRNA hsa-miR-3124:mirSVR_lowEffct hsa-miR-3124:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.86E-14 1.04E-10 3.27E-14 3.01E-13 30 110 "ACTN1,KCTD16,CDC14B,MARK4,CARMIL3,SNAI3-AS1,NGB,NMT2,CS,CSF1,SLC29A4,MBNL2,SLC37A3,DISC1,KDM2B,GRIK5,GRIN1,TOX2,TUBB2B,KHK,PSAT1,GON4L,GLDN,NUBPL,NAXD,NKAIN2,MCF2L,MTCH1,CELF4,DNALI1" MicroRNA hsa-miR-561-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-14 1.07E-10 3.34E-14 3.07E-13 34 141 "GALNT13,NR0B1,TAOK1,PCDH10,CADPS,CNN3,USP6NL,LONRF1,DMD,TMTC1,SH3GLB1,CELSR3,RCAN2,FUT10,NEGR1,RBPJ,LIX1,CHIC1,SESN3,ZNF713,PTCH1,ROBO1,FNDC3A,CPEB4,SON,TROVE2,SYPL1,ANKRD28,CRB1,RUNDC3B,VLDLR,ZNF138,PMEPA1,FXR1" MicroRNA hsa-miR-431*:mirSVR_highEffct hsa-miR-431*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.91E-14 1.07E-10 3.34E-14 3.08E-13 39 183 "ASIC2,SLITRK1,AP2A2,PPFIA1,PKP4,SYNJ2,JAZF1,SMARCAL1,MYADM,TCAF1,FRMPD4,INTS1,EGFR,VPS13B,FHL1,RGPD5,GABBR1,DIDO1,KHK,MMP16,SCG3,P2RY13,NF1,HMGCLL1,APTX,RDX,EXD2,DRAXIN,ELMOD1,ARHGEF40,STXBP1,CRB1,FBXL16,HEY1,ELP5,RFTN2,HIRA,SGK3,PRDM10" MicroRNA hsa-miR-3125:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-14 1.07E-10 3.34E-14 3.08E-13 39 183 "CPNE2,CASKIN1,C1QTNF1,SFMBT2,IGDCC4,BCL7A,BTF3L4,PYGO1,PHF19,IP6K1,DBN1,PLEKHM1,DNM2,AMOTL2,AFF2,CELF1,GAP43,CECR2,HSP90AA1,IDH3A,MID1,CCDC80,PABPC1L2A,DDR2,FIGN,ELP2,PRR5L,TRIM67,COA1,SON,DIP2A,SATB2,HIF3A,ZFP91,TUBB2A,WRN,ITM2C,WIPF2,C12orf4" MicroRNA hsa-miR-3185:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-14 1.12E-10 3.48E-14 3.21E-13 37 166 "TRMT9B,NCOA1,ATP2A2,ARHGEF7,CANX,CLCN3,CNGA3,VCAN,CTNND1,RIMS3,CHRDL1,NR1D2,GLUL,NEGR1,ZIC5,NAT8L,MOG,NELL2,OPHN1,PFKFB3,PACSIN1,MINDY2,MSANTD2,ALG9,ITPRID2,MPRIP,SATB2,AHCYL2,HIF3A,SLC44A1,ARL10,TPD52L2,WRN,SF1,PRDM10,ZDHHC20,FXR1" MicroRNA hsa-miR-518b:mirSVR_highEffct hsa-miR-518b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.99E-14 1.12E-10 3.48E-14 3.21E-13 37 166 "TTYH1,LRFN2,ZNF608,CFAP410,LGI1,CHGA,PPT2,SMARCAL1,SOCS5,ANKRD13B,ACSL4,FGFR1,FHL1,TACC2,NSG2,SYT17,CCDC184,ZHX1,MEIS2,KITLG,ZC3H12B,NDUFA5,ZNF827,PPP3CB,TMEM255A,RBBP8,ZDHHC14,FBXO11,MCF2L,NSD1,TGFBR3,HEY2,TSN,PLEKHH2,KCNK12,PRDM2,PARP11" MicroRNA hsa-miR-5580-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-14 1.12E-10 3.49E-14 3.21E-13 42 210 "ABCF1,FMNL2,TBRG4,CFL2,DAPK1,YAF2,ABI2,CERCAM,RCAN2,TRMO,ZBED3,FYN,GABRG1,GCK,MMADHC,NR3C1,IGFBP1,KCNB1,KLHL23,KCNK1,L1CAM,NEXMIF,NLGN3,PIK3R1,PTPRB,SH3TC2,GTDC1,ZNF532,CSRNP3,FAM19A1,ZFP30,CNKSR2,SEPHS1,SLC12A2,FAM126B,SOX5,HHIP,BEX4,KCNK12,ZBTB16,MFF,EVI5" MicroRNA "AGCTCCT,MIR-28:MSigDB" "AGCTCCT,MIR-28:MSigDB" MSigDB 2.09E-14 1.17E-10 3.66E-14 3.37E-13 27 89 "DPF1,ACHE,ARID1A,NDRG2,UNC5A,PDZD4,AMPH,CABP7,FOXN3,QKI,CNTFR,CSF1,NTM,DYRK1A,EN2,EPHB1,ZNF512,GPM6A,RNF165,HNRNPK,MAT2A,ZC3H12B,NNAT,ATXN1,IQSEC2,TRPS1,KAT6A" MicroRNA hsa-miR-6763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-14 1.22E-10 3.80E-14 3.50E-13 38 175 "CPNE2,AP1B1,CASKIN1,ARRB1,CACNB2,DIRAS1,CBS,TPP1,RGS6,PHYHIP,PLEKHM1,ABCC5,ING4,HBS1L,SRCAP,TNRC6A,SHISA6,SOWAHA,SCIN,MSI1,NBL1,GPR173,PTPA,C12orf49,RPS6KA2,DRAXIN,CLSTN1,LHFPL4,UNC5B,CLSTN2,CAMTA2,FAM168A,SLC19A3,CBX5,KCTD2,UBTF,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-3150a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-14 1.22E-10 3.80E-14 3.50E-13 38 175 "CPNE2,AP1B1,CASKIN1,ARRB1,CACNB2,DIRAS1,CBS,TPP1,RGS6,PHYHIP,PLEKHM1,ABCC5,ING4,HBS1L,SRCAP,TNRC6A,SHISA6,SOWAHA,SCIN,MSI1,NBL1,GPR173,PTPA,C12orf49,RPS6KA2,DRAXIN,CLSTN1,LHFPL4,UNC5B,CLSTN2,CAMTA2,FAM168A,SLC19A3,CBX5,KCTD2,UBTF,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.22E-14 1.25E-10 3.89E-14 3.58E-13 46 248 "NLGN4X,MTA3,DDO,ZNF582,THSD7A,CBR1,CCNT1,CDH2,RTTN,TOGARAM2,UBXN2A,ZEB2,FEM1B,EPHB1,TAOK3,FOXG1,PDLIM5,ZNF274,COPS8,GPR26,EID2B,RBPJ,KCNB1,MBNL1,SAMD5,PKM,SMIM7,POU3F2,CEP41,GDPD1,SNRK,MDGA2,ACSS3,RNASEL,EXD2,CARF,GSTCD,CCDC25,ACER3,TRAPPC13,MAGI3,SON,CLUAP1,NPAS3,TROVE2,RICTOR" MicroRNA hsa-miR-504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.32E-14 1.30E-10 4.06E-14 3.74E-13 60 391 "ABCF1,CLK4,XKR4,ADCY2,RNF157,ESYT2,KIF6,DOCK11,ISPD,AKAP5,DBT,KRBA2,HEYL,OPTN,TUBD1,SEC23B,CINP,SPECC1,GPR75,GLUL,CNDP1,LILRA2,GRB10,KAT7,SHISAL1,IBA57,LIMS1,GPR155,MKLN1,NASP,OLA1,ZNF655,PKM,GPSM2,PIGG,ZYG11B,PGBD4,SNX22,PTGR2,NCBP3,HSPA4L,SLITRK3,ANKRD36,ERC1,CDK19,SSTR2,MAPK8IP3,MPRIP,KLHL7,ALG1,WWC1,FBXW11,VWC2,GPR161,ZNF106,MEAF6,ZNF74,ZNF154,TIGD6,RNF170" MicroRNA hsa-miR-6858-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.38E-14 1.34E-10 4.16E-14 3.83E-13 34 142 "XKR4,API5,NEURL1,STOML1,NCOR2,UBXN2A,G3BP2,TOM1,APC2,ANKMY1,CELF1,TRAF3IP2,MYOZ2,CYP46A1,LYVE1,CRCP,GRK4,MKLN1,NODAL,STRN3,MAGEL2,FAT3,UEVLD,KCNIP2,NCBP3,FAM192A,DIP2A,AKNA,RBFOX2,TPD52L2,USP1,DHX33,WIPF2,MSRB3" MicroRNA hsa-miR-1274b:PITA hsa-miR-1274b:PITA_TOP PITA 2.43E-14 1.36E-10 4.25E-14 3.91E-13 37 167 "BRINP2,DOCK11,NRXN1,CNTNAP2,RIMS2,G3BP2,FAM135B,ANKFY1,SGIP1,GATM,GK,IL1RAPL1,BACH2,HNRNPK,SMAP1,GPR62,NEUROD1,NFIX,PRTG,PLP1,PURG,RETREG2,MED1,CNNM2,PTPRD,FIGN,ZNF532,SCN3A,LRRTM4,PPP4R3A,LHFPL4,UNC5D,TBL1X,SLC44A1,TIAM1,RBFOX2,VANGL2" MicroRNA hsa-miR-548p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-14 1.60E-10 4.98E-14 4.59E-13 35 151 "FAM135A,DST,MAP7,HINFP,UBXN2A,DCAF8,SPATA2,TMTC1,MTHFD2,NKD1,IL6ST,KCNN3,LAMP2,PABPC1L2A,GPR137C,GPR85,LRP12,SPATA6,SLC36A4,CNNM2,PXK,KLHL11,CSRNP3,ATF7IP,PEG10,CDK19,SYPL1,CLASP1,ZMAT3,CBX5,DDHD1,ZFP91,TUBB2A,RPL7L1,NDRG4" MicroRNA hsa-miR-3180-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.97E-14 1.67E-10 5.19E-14 4.78E-13 34 143 "SEMA7A,APBB2,ZNF582,UBXN2A,PLEKHM1,RASGRP1,REEP2,CEP78,AFF2,CELF1,ZNF274,GPM6B,PARD3B,SLC6A17,XRRA1,ZNF827,ZNF426,MTRF1L,PRKCB,MDGA2,UBR7,SETD5,ELP2,RXRA,SGK1,SON,CLSTN2,ANKRD28,ZFP91,ZNF384,CSDE1,XKR7,URM1,NELFE" MicroRNA "TTGGAGA,MIR-515-5P:MSigDB" "TTGGAGA,MIR-515-5P:MSigDB" MSigDB 3.00E-14 1.69E-10 5.24E-14 4.83E-13 33 135 "ARID1A,TMEM263,NCOA1,DDX3Y,SLC4A4,BSN,OSBPL3,PUM1,POM121,G3BP2,CPEB2,EFNA3,YAF2,EMX2,ETV1,GABBR1,CAB39,MAEL,KCND2,MSI1,OPHN1,PDGFRA,SCN8A,ITSN1,EPN2,SNAP25,SP4,CLSTN2,TACC1,AHCYL2,ZFP91,UBE2H,NSD2" MicroRNA "TTGGAGA,MIR-519E:MSigDB" "TTGGAGA,MIR-519E:MSigDB" MSigDB 3.00E-14 1.69E-10 5.24E-14 4.83E-13 33 135 "ARID1A,TMEM263,NCOA1,DDX3Y,SLC4A4,BSN,OSBPL3,PUM1,POM121,G3BP2,CPEB2,EFNA3,YAF2,EMX2,ETV1,GABBR1,CAB39,MAEL,KCND2,MSI1,OPHN1,PDGFRA,SCN8A,ITSN1,EPN2,SNAP25,SP4,CLSTN2,TACC1,AHCYL2,ZFP91,UBE2H,NSD2" MicroRNA hsa-miR-379:PITA hsa-miR-379:PITA_TOP PITA 3.29E-14 1.85E-10 5.74E-14 5.28E-13 25 77 "HECW2,MTMR2,MAGI1,IGDCC3,EDN1,EIF4G2,ERBB4,UBE2E3,PCDH17,RAB30,CACFD1,MAP4K5,IDH3A,KCNK2,KIF5A,NAP1L1,MINDY2,RET,HSPA4L,CCDC88A,CDK19,MMS19,ADGRL3,TCF4,SYNC" MicroRNA hsa-miR-125a-3p:Functional MTI Functional MTI miRTarbase 3.29E-14 1.85E-10 5.75E-14 5.30E-13 52 310 "TMEM132B,PNMA8B,TXNDC16,AK2,TAOK1,ARRB1,ARRB2,CACNB2,CFL2,STOML1,BTF3L4,FAM131B,DPYSL2,GNE,BSCL2,WAC,IP6K2,FYN,FAXC,GLUL,POLL,GNAS,CECR2,MFSD2A,DDX19B,ATCAY,C2orf72,ZIC5,KCNN1,KCNN3,GIT1,P2RX7,TMOD2,PFKFB2,PIK3C2A,PIGG,NWD1,PRRT2,DCUN1D2,HUNK,HSPA4L,SGK1,ZNF430,SLC15A2,CLUAP1,ZBTB43,STAC2,TPM2,ZNF708,ZNF74,DPYSL5,FXR1" MicroRNA hsa-miR-503-5p:TargetScan hsa-miR-503-5p TargetScan 3.32E-14 1.87E-10 5.80E-14 5.34E-13 42 213 "ACHE,ARHGAP20,PPFIA3,CCAR2,CDK5R1,CACNA1I,BSN,BTRC,FOXK1,CAST,AIFM1,HECTD1,KLHL3,POM121,FAM57B,EIF4G1,ANKRD13B,RAB9B,GHR,NCKAP1L,C2orf72,NKD1,KIF5A,KIF5C,AQP11,MYO5A,NFYA,OCRL,KCNK10,PIK3C2A,ANLN,PIK3R1,EPB41L4B,PPP3CB,RASGEF1B,CNNM2,CYB561D1,HSPA4L,NMNAT2,CBX5,RICTOR,GAN" MicroRNA hsa-miR-4485-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-14 1.87E-10 5.82E-14 5.36E-13 39 186 "CLK4,FOXK1,CACNA1A,ZNF385A,ZBTB24,HEYL,TUBD1,SLC43A2,FGFR1,PCYOX1,NCKAP1,MYOZ2,CRCP,CNDP1,KIF3A,HMGB1,ATCAY,ZNF655,FAM216A,STRN3,EXOSC10,APTX,PTAFR,MTMR10,ZSCAN2,ZNF844,NWD1,PGBD4,SEPHS1,ATF7IP,CLUAP1,DIP2A,AGTPBP1,ACSL6,ZMAT3,ZNF384,SSBP2,LINC00632,JMJD1C" MicroRNA hsa-miR-28-5p:Functional MTI Functional MTI miRTarbase 3.51E-14 1.97E-10 6.13E-14 5.65E-13 29 105 "PLEKHG5,CNN3,CS,NOS1AP,CTIF,E2F6,NRN1,TUBB4A,PCYOX1,AHDC1,PRRC2B,RNF165,IGF1,KCNH2,RETREG2,KLHL11,DRAXIN,MYH15,IQSEC2,FAM168A,ZNF106,THRA,ZFP91,IL34,TPM4,TUBB2A,PRDM2,AAAS,PIANP" MicroRNA hsa-miR-1308:PITA hsa-miR-1308:PITA_TOP PITA 3.51E-14 1.97E-10 6.13E-14 5.65E-13 29 105 "SLITRK1,OSBPL8,TMEFF1,MARK4,ZEB2,PLEKHM1,MAGI2,ALKBH8,CPEB2,DPYSL2,EFNB3,DCTN4,ACSL4,ZIC4,PPARGC1A,RAB30,KLF12,KITLG,MITF,TCEAL5,NLGN3,ZSCAN32,TMEM255A,ELMOD1,ADAMTS17,TAL1,NR2E1,LRP8,SLC17A6" MicroRNA hsa-miR-361-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-14 2.08E-10 6.44E-14 5.94E-13 34 144 "MARCH4,LRFN1,LGR5,ARHGDIA,ARRB2,BCL2L2,SH2B1,LRIG1,VCAN,TBC1D5,IP6K1,DMPK,ATN1,FAM135B,MRPL37,APC2,IP6K2,SEMA4D,GPD1,LSAMP,MAOB,NFYA,VWA2,KSR2,ATXN1,NPAS3,SMOC1,GSE1,ZC3H4,ALG1,CADM1,ZBTB16,CIAPIN1,VANGL2" MicroRNA hsa-miR-1237-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-14 2.08E-10 6.44E-14 5.94E-13 34 144 "RALGAPA1,XKR4,FMNL2,GALNT13,RNF157,ADD1,NLGN4X,SPOP,SFMBT2,B4GALT6,PLCXD3,TM9SF4,CPEB2,OPTN,EMX2,EPHB1,ST3GAL6,ZMAT1,DIPK1C,NR3C1,HMGB1,NEGR1,IBA57,KCNN3,MDGA1,PDE3A,RASGEF1B,KCNIP3,ZNF430,EXOC7,SZT2,ZNF106,TNS1,TPD52L2" MicroRNA hsa-miR-223-3p:Functional MTI Functional MTI miRTarbase 3.76E-14 2.11E-10 6.55E-14 6.04E-13 28 98 "ATM,PTBP2,SCARB1,CDC27,TOX,PHF19,F3,FABP7,FOXO3,IL6ST,STMN1,LMO2,MEF2C,SESN3,NFIA,NFIX,NOVA2,PAX6,ABCB1,MTRF1L,FBXW7,ZNF365,NMNAT2,EPB41L3,PRRC2C,TAL1,ZEB1,NLRP3" MicroRNA hsa-miR-4724-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.76E-14 2.11E-10 6.55E-14 6.04E-13 28 98 "HFM1,ABCD2,CASK,ATP1B3,STX16,ZNF555,ABCG2,NRG2,PYGO1,SPATA2,YTHDC1,G3BP2,MAMLD1,DNAJB6,RASSF8,HSP90AA1,ZIC5,STMN1,ZNF680,BEST3,PRKACB,SEC61A2,MCMBP,SLC30A10,GPRIN3,SLC35G2,TPM3,ZNF17" MicroRNA hsa-miR-7113-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.04E-14 2.27E-10 7.03E-14 6.48E-13 41 205 "RNF150,BACH1,NIPA1,CACNA1A,CCNT1,CDH8,QKI,AKAP5,RTTN,PITPNM3,CYBB,SPATA2,SMG7,IRAK4,EMX2,SRARP,TACC2,UFM1,CELF1,SRRM4,GJB1,ZNF638,GRID1,RFFL,SHISA6,KCNH1,KCNJ11,KCNQ3,LSAMP,MBNL1,NOVA2,ZDHHC22,BEST3,MTMR10,PTPRG,PEX26,CLUAP1,LRRC4,DIP2A,TMEM178B,IQCE" MicroRNA hsa-miR-328-3p:TargetScan hsa-miR-328-3p TargetScan 4.34E-14 2.44E-10 7.56E-14 6.96E-13 35 153 "ASIC1,GRAMD1B,KIAA1614,FUBP1,HAP1,FMNL3,RAB3C,NRG2,CTIF,DYNC1I1,HEYL,EN2,EPB41L1,CACNG2,HPCAL4,ANKFY1,GBX2,LYVE1,NR3C1,MFSD2A,PADI2,NXPH3,KIF2A,MMP16,MN1,MXI1,SDK2,GTDC1,LGR4,SCN2B,FAM214B,CCDC88A,RAP1GAP2,KAT6B,POLR3H" MicroRNA hsa-miR-31-5p:Functional MTI Functional MTI miRTarbase 4.43E-14 2.49E-10 7.71E-14 7.10E-13 43 224 "ARID1A,PHF12,DACT3,NUMB,ATP2A2,JAZF1,CCNT1,MAP4K4,RHOBTB1,DMD,MED12,RASA4,MTSS1L,FOXO3,NOP56,WASF3,GLI2,PCSK1N,PRRC2B,LILRA2,GYG1,ZNF678,STMN1,PPM1L,AFF1,MMP16,ZIK1,RAB5B,RDX,RET,MCMBP,ZNF331,SLC1A2,MPRIP,SATB2,AKNA,TIAM1,TMEM9,RPL7L1,DPYSL5,EMSY,PARP11,FZD3" MicroRNA hsa-miR-6840-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.55E-14 2.55E-10 7.91E-14 7.28E-13 65 452 "ABCF1,SLC12A5,PTCHD1,MTA3,HACE1,APAF1,CPNE5,AQP6,ATM,FOXK1,CBS,CCPG1,GPR37L1,SUMF2,RTTN,ACBD5,ZNF385A,RNF14,PYGO1,MYADM,FGFR1OP2,IP6K1,HP1BP3,MTX3,DNAH9,DNM2,CNNM1,HEYL,MRO,ANKMY1,ZNF589,MSANTD4,BRPF3,KIAA1958,GNG3,GNG4,KIF3A,BACH2,AGBL5,IGF1,NKD1,IL6R,NFIX,NRGN,FAM216A,TNPO2,FAT3,NCR3LG1,ZNF844,CEP97,MSANTD2,RGS12,CSRNP3,SLC30A10,MAGI3,TRIM67,ATF7IP,ACSBG1,VAMP1,ACSL6,AHCYL2,ERCC6L2,TSPAN11,LAT2,INTS3" MicroRNA hsa-miR-4448:Functional MTI Functional MTI miRTarbase 4.60E-14 2.58E-10 8.00E-14 7.37E-13 25 78 "RNF157,TBC1D14,ZBED1,TBPL1,CSNK1E,PLEKHO1,DNAJC27,AMOTL2,SRRM4,POLL,GRID1,HMX1,HMGCLL1,TNPO2,ZNF568,SLC6A8,CCDC88A,TRIM67,PDZD2,POGZ,SEPT8,PRRC2C,STXBP4,WNK1,WIPF2" MicroRNA hsa-miR-411-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.65E-14 2.61E-10 8.08E-14 7.44E-13 42 215 "TAOK1,ABCD2,C6orf89,API5,ATP1A2,WASF1,CDH2,AKAP6,COL9A2,HINFP,CSNK1E,KIAA0586,GNE,WDPCP,EIF4G2,PLEKHA1,C8orf37,EPB41L1,GABRB1,TRAF3IP2,GALR1,MYOZ2,ZNF276,GRM3,DDX19B,KPNA5,GPR155,PAK3,GDAP1L1,MINDY2,ZNF793,NWD1,ZYG11B,FAM161B,ZNF621,ATMIN,KIAA0930,TRIM2,GPRIN3,SSBP2,ZNF708,WNK3" MicroRNA hsa-miR-216b-5p:Functional MTI Functional MTI miRTarbase 4.72E-14 2.65E-10 8.21E-14 7.56E-13 33 137 "AS3MT,FZD9,PDZD4,CDC42BPA,APAF1,ZNF583,ZBED1,SOCS6,UBXN2A,CENPL,TM9SF4,RIMS3,MRNIP,C8orf37,FOXM1,KLF12,NKD1,ZIC5,SMAD1,MID1,P2RX7,PRKAB2,SP4,DNAJC9,TMEM178B,SLC19A3,TPM3,SSBP2,WRN,ZBTB38,ZFAND5,MPPE1,NUP214" MicroRNA hsa-miR-4524b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.87E-14 2.73E-10 8.46E-14 7.79E-13 44 234 "TEX22,AP1B1,ARHGDIA,ARSE,ALDH4A1,ATP1A2,FOXK1,TMEM184B,RNF14,SEC14L5,RCAN1,RASGRP1,GABRB1,FAM184B,ZNF274,MYOZ2,GCK,CSDC2,PPARGC1A,PTPRT,SCRG1,NEGR1,IDH3A,KIT,P2RX7,PLXNB1,MINDY2,KANSL1,RAB3A,ZYG11B,RTKN,RMI1,FOXRED2,BDP1,SPART,EPB41L3,ACSL6,USP22,NACC2,VAV2,TBC1D15,ZNF74,DPYSL5,URM1" MicroRNA hsa-miR-450b-3p:PITA hsa-miR-450b-3p:PITA_TOP PITA 5.05E-14 2.84E-10 8.78E-14 8.08E-13 26 85 "ATP2B1,CLDN10,USP6,DLGAP3,FRMPD4,MYEF2,HP1BP3,DLG2,APH1A,GAP43,STARD10,FAM19A2,CELF3,HLF,MEIS2,MKLN1,NOVA1,NPTX1,PBRM1,CCDC92,WDR47,SMARCE1,SOX2,LARP4,HEY2,INTS3" MicroRNA hsa-miR-875-5p:PITA hsa-miR-875-5p:PITA_TOP PITA 5.27E-14 2.96E-10 9.15E-14 8.43E-13 30 114 "ESYT2,PPP4R4,DDX3Y,NIPA1,BTF3L4,CLOCK,TRIM69,CPEB2,DYRK1A,EYA1,TAOK3,STAG2,NEGR1,AQP11,PDE4D,RETREG1,SEMA6D,NLGN4Y,PPM1E,SP2,SRPK2,ITPRID2,VAMP1,SYPL1,TCF4,SATB2,TCF12,SYNE1,KAT6A,PHTF2" MicroRNA hsa-miR-1245a:Functional MTI Functional MTI miRTarbase 5.27E-14 2.96E-10 9.15E-14 8.43E-13 30 114 "AS3MT,GOLGA7B,SFMBT2,ARSE,PDE4DIP,MYADM,SIRPA,SUCO,APOPT1,MSANTD4,SRCAP,GRB10,RASSF8,HAS2,MAN2A2,LYPLAL1,CHST6,MYO5A,OCRL,ZNF426,GSTCD,ROBO1,CSRNP3,ANKRD36,CLUAP1,ZNF34,RICTOR,WIPF2,MPPE1,TMEM63C" MicroRNA hsa-miR-6864-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.37E-14 3.02E-10 9.31E-14 8.58E-13 53 324 "AS3MT,CC2D2A,TAOK1,TRMT9B,APP,PDXK,ISPD,CBS,TBRG4,COL9A2,LETMD1,IFFO1,RTTN,SOCS5,USP6NL,GAPVD1,ST8SIA3,MRO,EGR3,DCTN4,ZNF549,PCYOX1,GABRB1,SIGLEC8,KIAA1841,FAXC,SRCAP,OS9,LINC01551,DDX19B,ZDHHC15,C5orf24,SCIN,IBA57,KCNN3,MBD1,MOG,OLR1,CCSER2,SMIM7,STRN3,CNTLN,MTMR10,KLHL11,ZNF331,SEPHS1,RAB3GAP1,ARHGAP26,ERBIN,AHCYL2,VSNL1,LYPD6,PHTF2" MicroRNA hsa-miR-3672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.37E-14 3.02E-10 9.31E-14 8.58E-13 53 324 "AS3MT,CC2D2A,TAOK1,TRMT9B,APP,PDXK,ISPD,CBS,TBRG4,COL9A2,LETMD1,IFFO1,RTTN,SOCS5,USP6NL,GAPVD1,ST8SIA3,MRO,EGR3,DCTN4,ZNF549,PCYOX1,GABRB1,SIGLEC8,KIAA1841,FAXC,SRCAP,OS9,LINC01551,DDX19B,ZDHHC15,C5orf24,SCIN,IBA57,KCNN3,MBD1,MOG,OLR1,CCSER2,SMIM7,STRN3,CNTLN,MTMR10,KLHL11,ZNF331,SEPHS1,RAB3GAP1,ARHGAP26,ERBIN,AHCYL2,VSNL1,LYPD6,PHTF2" MicroRNA hsa-miR-543:Functional MTI Functional MTI miRTarbase 6.01E-14 3.38E-10 1.04E-13 9.60E-13 29 107 "ADD1,AMPD3,ATM,EIF4G3,BACH1,CLTC,SOCS5,RUBCN,MATR3,FAM13A,EN2,EPS8,NCOA7,MDM4,MN1,PTK2,SPDL1,STX1B,MYO18A,SHC4,FBXO11,FNDC3A,SYNE2,ADAMTS17,MTCL1,SIRT1,ZNF711,EML6,CSDE1" MicroRNA "GTGGTGA,MIR-197:MSigDB" "GTGGTGA,MIR-197:MSigDB" MSigDB 6.13E-14 3.44E-10 1.06E-13 9.78E-13 23 66 "PCDH19,ANK2,BCL7A,RAB28,SLC32A1,CTNND1,DNM1,PHF20L1,AGAP2,GRIA2,GRIN1,KCND2,ZNF827,MAPK4,TTLL7,FBXW7,KCNIP2,PPM1E,NLGN1,TAL1,ADGRL3,ZIC3,PIANP" MicroRNA "CTAGGAA,MIR-384:MSigDB" "CTAGGAA,MIR-384:MSigDB" MSigDB 6.35E-14 3.57E-10 1.10E-13 1.01E-12 22 60 "PCDH19,HFM1,AQP4,CHRD,FOXN3,SLC35F1,RIMS4,RIMS2,POM121,SRGAP3,UBE2E3,ATP2C1,GFRA2,GPM6B,CD200,NCAM1,PRKACB,SYTL2,PTN,FBXO11,ERBIN,NAV2" MicroRNA hsa-miR-203b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.46E-14 3.63E-10 1.12E-13 1.03E-12 37 172 "KIAA1211,PHF12,SEMA4G,CACNB2,PNKD,SEC24C,SOCS5,GAPVD1,GNE,CRCP,ATCAY,KCNN3,CREG2,MDM4,SLC11A2,TMOD2,SLC36A4,PIGG,NCR3LG1,ERI2,FNIP1,HSPA4L,SH3BP2,NUBPL,PEX26,ANKRD36,ERC1,SSTR2,STAC2,KLHL7,SLC19A3,DDHD1,RBFOX2,ZNF708,PRDM2,MPPE1,GAN" MicroRNA hsa-miR-411:PITA hsa-miR-411:PITA_TOP PITA 6.60E-14 3.71E-10 1.14E-13 1.05E-12 28 100 "DPP10,PPFIA2,WASF1,CACNB4,CDH2,CCPG1,KIAA1549L,MAP4K4,SLC4A7,PUM1,FRMPD4,FBXL5,KLHL3,EIF4G2,CAMSAP1,GRM3,CD200,GKAP1,SOX11,SP2,SP4,VAMP1,SYT4,TRPS1,ZFAND5,NAV3,WNK3,HNRNPA3" MicroRNA hsa-miR-631:PITA hsa-miR-631:PITA_TOP PITA 6.60E-14 3.71E-10 1.14E-13 1.05E-12 28 100 "ADCY6,NCOA1,RUNX1T1,ZNF385A,ERC2,FAM131B,DYRK1A,CNNM1,DMTN,PSD2,LPAR4,RNF165,C1orf94,STMN1,MAT2A,MBNL1,ZC3H12B,KCNIP2,ATXN1,AMBRA1,EPN2,SLC12A2,NCDN,CLASP1,THRA,TMEM237,SMARCAD1,STMN4" MicroRNA hsa-miR-1260b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-14 3.79E-10 1.17E-13 1.08E-12 48 275 "RNF150,MTA3,OSBPL1A,APBB2,AMER3,APP,DDX3Y,BACH1,CACNA1A,PRC1,CD81,GAPVD1,RIPOR2,TOMM20,IP6K1,ABI2,EIF4G1,SORBS3,ELAVL3,TNK2,MRPL37,GABRB1,KIF3A,HNRNPK,MN1,CD200,OGG1,RETREG1,PKM,PSAT1,CNNM2,GSTCD,RPE,SPIN3,SCP2,STUM,KIF21A,DHX30,KANSL3,SMARCE1,ZCCHC24,CLUAP1,SMOC1,JMJD6,UGT8,MTCH1,HNRNPA3,GAN" MicroRNA hsa-miR-3161:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-14 3.81E-10 1.18E-13 1.08E-12 30 115 "SPOP,GAS7,CBR1,QKI,UBXN2A,CTNND1,TOMM20,RASGRP1,CACNG7,ABI2,EIF4G2,ZBED3,NUDT21,IL1RAPL1,ELOVL5,MBNL1,PAX6,ENOX1,ZFHX4,SLC8A1,DIP2A,TPCN2,DOK6,NR2C2,TOM1L2,VLDLR,VSNL1,STOX2,WIPF2,NETO2" MicroRNA hsa-miR-769-3p:PITA hsa-miR-769-3p:PITA_TOP PITA 6.89E-14 3.87E-10 1.19E-13 1.10E-12 26 86 "ATP2B1,CLDN10,USP6,DLGAP3,FRMPD4,MYEF2,HP1BP3,DLG2,APH1A,GAP43,STARD10,FAM19A2,CELF3,HLF,MEIS2,MKLN1,NOVA1,NPTX1,PBRM1,CCDC92,WDR47,SMARCE1,SOX2,LARP4,HEY2,INTS3" MicroRNA hsa-miR-1301-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.89E-14 3.87E-10 1.19E-13 1.10E-12 40 199 "ADD2,SEMA6A,USP28,DST,SYNJ2,CCNH,CHN1,NCOR1,CSNK1G3,PHF19,MAGI2,YAF2,FAM13A,MRPL10,FECH,CELF1,CAB39,TXNL4A,GLUL,KIAA1958,ATXN2L,NAT8L,MBNL1,ZNF680,NBL1,PKM,CDIP1,ACER3,CPEB3,CDK5RAP2,SON,ZCCHC24,TMPO,TP53BP2,WBP2,RUNDC3B,RFTN2,BCL2L13,POLR3H,WIPF2" MicroRNA hsa-miR-644a:Functional MTI Functional MTI miRTarbase 6.93E-14 3.89E-10 1.20E-13 1.10E-12 27 93 "ELFN2,CARNS1,LDHD,CACNA1A,SLC22A6,TMEM184B,IGLON5,ENTPD4,CREB5,DCAF8,TMEM130,DMTF1,C8orf37,MRPL37,CAMKK2,PRRC2B,IL1RAPL1,NKD1,MAP2,MPP2,NOS1,SDK2,SATB1,NCDN,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-451:mirSVR_highEffct hsa-miR-451:mirSVR_conserved_highEffect-0.5 MicroRNA.org 7.18E-14 4.03E-10 1.24E-13 1.14E-12 43 227 "BEND6,CC2D2A,CDC14B,DCAF5,B4GALT6,RRAGB,SGIP1,NPTN,CAB39,SESN1,GK,MSL3,KDM2B,MCHR1,ZBTB49,TCEAL6,RBPJ,ZNF678,MBP,MOBP,DPY19L2P2,MAGEL2,POU3F2,PTPRE,DBX2,SETD5,SGK1,SORCS3,MYO16,CAND2,ZNF423,KIF1B,KLHL7,SYNE2,ADGRL3,CUX2,AKTIP,TK2,ZIC3,TCEAL7,ZNF184,CA10,EMSY" MicroRNA hsa-miR-214-5p:TargetScan hsa-miR-214-5p TargetScan 7.37E-14 4.14E-10 1.27E-13 1.17E-12 33 139 "PWWP2A,HECW2,IGDCC4,MTMR3,HAP1,CDC27,CFL2,ARMC8,CRY2,FAM169A,CTIF,CNNM1,IQCG,EFCAB2,GBX2,GFRA1,RAB30,KCNMB4,KLF12,KIAA1755,MBNL1,AFF1,DBNL,NELL2,PDE3B,PDGFRA,GPR173,CEP41,RORB,HSPA4L,CNTN2,CBX5,DPYSL5" MicroRNA hsa-miR-6858-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.46E-14 4.19E-10 1.29E-13 1.19E-12 32 131 "AK2,APBB2,CACNA1B,GAPVD1,CTIF,SEC16A,BSCL2,EIF1,EN2,ANKRD13B,MRVI1,SYNCRIP,PDLIM5,PRRC2B,METTL21A,PDE3A,ZNF426,TNPO2,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,WDTC1,NMNAT2,PEG10,ZC3H4,ZMAT3,TNS1,RASD2,SF1,WIPF2" MicroRNA hsa-miR-4443:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.82E-14 4.39E-10 1.35E-13 1.24E-12 29 108 "PLEKHG5,PNMA8B,CASKIN1,KIF6,CLU,NCOR2,CS,RASSF2,SGSM2,RTN3,DOT1L,NEURL4,CSDC2,NEGR1,KLHL23,SAMD5,TMOD2,PLEC,POLG,RAB5B,SETD5,NCBP3,TRIM67,PEG10,ZSCAN29,SSBP2,TUBB2A,SMARCAD1,INTS3" MicroRNA hsa-miR-517b:PITA hsa-miR-517b:PITA_TOP PITA 7.84E-14 4.40E-10 1.35E-13 1.25E-12 20 49 "CPNE2,CAMK2G,NRXN1,ERC2,MATR3,ZEB2,KATNAL1,GLRB,ATF7,LRRTM3,OLFM3,MEIS2,MITF,SMPD3,SHC4,TBX15,TSC1,TMEM198,PRDM8,MPPE1" MicroRNA hsa-miR-4781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-14 4.48E-10 1.38E-13 1.27E-12 41 209 "SDE2,TRMT9B,ATP1A2,DCAF5,AKAP6,BAG4,CSNK1E,SEC14L5,FGFR1OP2,PHF19,KIAA0586,YTHDC1,BLOC1S6,RABGAP1L,TRMO,DOT1L,ZNF546,CREG2,CYP27C1,LAYN,MYO6,NUCB1,PAK3,MINDY2,OXR1,SGSM1,NUBPL,PEX26,FAM126B,KIF1B,ZNF621,SSTR2,STAU1,ALG1,AGTPBP1,TMPO,SGK3,ZNF70,ZNF154,AP3B2,GAN" MicroRNA hsa-miR-205-5p:Functional MTI Functional MTI miRTarbase 8.14E-14 4.57E-10 1.40E-13 1.29E-12 38 182 "ABCF1,SLC25A25,KCTD16,PHF12,B4GALT6,RGS6,ZEB2,GUCD1,E2F5,PHC2,KLHL5,ERBB2,RTN3,ZNF585B,ACSL4,SARAF,GNAS,NUDT21,HMGB1,SHISA6,EID2B,KCNJ10,SMAD1,AFF1,MED1,SPDL1,LRRK2,CLIP1,LRRTM4,CPEB3,BDP1,VAMP1,DMXL2,SATB2,ZEB1,AMOT,SLC38A1,JMJD1C" MicroRNA hsa-miR-6756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.14E-14 4.57E-10 1.40E-13 1.29E-12 38 182 "ASGR1,DCAF5,CBS,NUMBL,TENM4,PLCXD3,CYBB,FGFR1OP2,IP6K1,KIAA0319,CALN1,KLHL5,PHF20L1,STARD3NL,CDHR1,REEP2,WAC,UFM1,CELF1,GALC,KCNMB4,HSP90AA1,METTL21A,STMN1,LSAMP,MDFI,MYO5A,NASP,DDR2,POU6F1,GTDC1,TMLHE,KIRREL1,SHANK2,MAPK8IP3,LAT2,PMEPA1,CERS6" MicroRNA hsa-miR-105*:mirSVR_highEffct hsa-miR-105*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.71E-14 4.89E-10 1.50E-13 1.38E-12 30 116 "SYN3,CLK4,B3GALT2,NRP2,CHGA,CNTFR,CFAP61,SRRM1,SYNCRIP,NELFCD,GNAS,GRIN2D,GRM7,GUCY1B1,MYCN,NEFH,NELL1,ZDHHC8,HERC2P3,HYDIN,UHRF1BP1,ZSCAN32,RFX4,NTNG1,RPGRIP1L,TTC3,RPRM,VLDLR,PRTFDC1,CERS6" MicroRNA hsa-miR-545-3p:Non-Functional MTI Non-Functional MTI miRTarbase 8.87E-14 4.98E-10 1.53E-13 1.41E-12 36 165 "DST,ACBD5,CSNK1G3,VCAN,UBXN2A,PLEKHM1,FAM13A,PLEKHA1,EN2,ANKMY1,MSANTD4,BRPF3,DISC1,NEGR1,DHX35,RBPJ,ARHGAP12,MDM4,CCDC80,GPR137C,PSAT1,PLEKHB2,ZFHX4,SETD5,RPL15,PEX26,SYP,SYPL1,ZMAT3,MTMR14,ZFP91,TPM3,TUBB2A,RPL7L1,NDRG4,FXR1" MicroRNA hsa-miR-6507-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.37E-14 5.26E-10 1.61E-13 1.49E-12 32 132 "NLGN4X,HECW2,SEMA4G,ZBTB10,CDK5R1,PRC1,ARHGEF4,MTX3,FAM107B,EIF4G2,ACSL4,FER,CAMSAP1,ZMAT1,NXPH2,MIER3,ZIC5,LIMS1,NCAM2,NELL2,SNX10,XRN1,ZNF426,PURG,RAB5B,SETD5,ACER3,CSRNP3,SGK1,AGTPBP1,HHIP,ACTR6" MicroRNA hsa-miR-2116-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.87E-14 5.54E-10 1.70E-13 1.57E-12 35 157 "GRAMD1B,PWWP2A,PTCHD1,PHF12,AMER3,ARSE,ATP2B1,ZNF582,CASTOR3,FOXK1,CAMK2G,EXOG,HIPK3,TUBB4A,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,SRRM4,FAXC,GPR26,GRK4,AP4S1,NFYA,PAK3,GDPD1,ZNF844,ZCCHC24,UHRF1BP1L,ACSL6,SMUG1,RUNDC3B,TSPAN11,DPYSL5,GAN" MicroRNA hsa-miR-764:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.98E-14 5.60E-10 1.72E-13 1.58E-12 46 258 "PLEKHG5,TMEM132B,TAOK1,ARRB1,FOXK1,CACNB2,STOML1,FAM131B,YTHDC1,GNE,BSCL2,WAC,FAXC,POLL,MFSD2A,DDX19B,ATCAY,RAB41,C2orf72,ZIC5,KCNN1,KCNN3,P2RX7,GPR137C,TMOD2,PIK3C2A,PKM,PIGG,NWD1,PRRT2,DCUN1D2,KLHDC8A,HUNK,HSPA4L,ZNF430,SLC15A2,INAVA,CLUAP1,ZBTB43,ZNF621,STAC2,CYB561A3,ZNF708,XKR7,FXR1,AP3B2" MicroRNA hsa-miR-875-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-13 5.70E-10 1.75E-13 1.61E-12 29 109 "BEND6,MTA3,ATP1B3,CANX,ISPD,CLCN3,TMEM184B,DCAF4,EPB41,CELF1,TMEM151A,ZNF44,GNAS,NUDT21,CYP27C1,PLEC,PPP3CB,C1orf109,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,TBCEL,TMPO,SSBP2,ZKSCAN5,NDRG4,SLC30A4" MicroRNA hsa-miR-532-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-13 5.93E-10 1.82E-13 1.67E-12 42 220 "PWWP2A,PTCHD1,PHF12,APP,ARSE,ATP2B1,ZNF582,FOXK1,CACNA1A,CAMK2G,CRY2,FGFR1OP2,RIPOR2,CELSR3,ABI2,ELAVL3,TUBB4A,AMOTL2,ANKFY1,TRAF3IP2,RAPGEF6,FAXC,POLL,GNAS,HAS2,CD200,NFYA,PAK3,PNMA3,PTAFR,ZNF844,SH3TC2,GSTCD,SCMH1,ZCCHC24,CLUAP1,ACSL6,SMUG1,RUNDC3B,TSPAN11,DPYSL5,GAN" MicroRNA hsa-miR-582-5p:Functional MTI Functional MTI miRTarbase 1.07E-13 6.03E-10 1.85E-13 1.70E-12 34 149 "TRMT9B,CAPRIN2,CD81,PDE4DIP,ZC3H11A,EIF4G2,ELAVL3,FLT1,NCKAP1,TNRC6A,DIDO1,DDX19B,ZDHHC15,HSP90AA1,ZNF678,KCNB1,KCNC1,MYCN,PABPC1L2A,NAP1L1,SLC11A2,PAK3,PIK3CD,PPP2R5E,QDPR,PGBD4,LRRK2,DICER1,TGFBR3,TPM4,TSN,RPL7L1,CFAP298,GAN" MicroRNA hsa-miR-548az-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-13 6.05E-10 1.85E-13 1.71E-12 36 166 "XKR4,PTCHD1,PHF12,APP,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CFL2,CLOCK,ENTPD4,ABI2,STARD3NL,SCML2,SUCO,RNPS1,GRK4,HMGB1,SCIN,KLRC3,DDR2,TNPO2,CRLS1,KANSL1,GRAMD1C,DIRAS2,TMLHE,CLUAP1,TUBB2A,PITPNB,EML6,SMARCAD1,WNK1,NHSL1" MicroRNA hsa-miR-486-3p:Functional MTI Functional MTI miRTarbase 1.16E-13 6.49E-10 1.99E-13 1.83E-12 40 202 "NDRG3,ELFN2,CASKIN1,TXNDC16,AMH,OGT,PHF12,BCL7A,HCN2,CAMK2A,BRSK2,CACNA2D2,PLXNA4,MYADM,IP6K1,SPATA2,DNAJC6,MRNIP,ERBB2,WAC,AHDC1,GFER,CRCP,POLL,B4GALNT4,ELOVL5,MAP4,MDM4,HS6ST3,PKD1,POLR2F,RXRA,SARS,COPZ1,TMCC1,NSD1,NACC2,TMPRSS5,TUBB2A,CIAPIN1" MicroRNA hsa-miR-1470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-13 6.60E-10 2.02E-13 1.86E-12 39 193 "PNMA8B,ARRB1,ARSE,CDH8,SLC22A6,TOGARAM2,TENM4,PLCXD3,PHF19,KIF26A,TMEM170A,SMG7,WDPCP,EMX2,SRARP,PDLIM5,GABRG2,RAB30,KIAA1958,NKD1,METTL21A,LSAMP,MDFI,MYO5A,NEXMIF,GTDC1,WDR37,BTBD3,SHANK2,INKA2,ZSCAN29,NSD1,CRTC1,KCNK12,ZBTB16,AMZ1,ZNF225,URM1,JPH3" MicroRNA hsa-miR-4304:mirSVR_highEffct hsa-miR-4304:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.22E-13 6.86E-10 2.10E-13 1.93E-12 25 81 "FAM135A,PITPNM2,CDK10,ARHGEF7,TIGD7,RAB33A,SLC4A8,KBTBD11,DNM1,DNM2,KMT5B,ANKMY1,CEP78,COPS8,RAB30,GRIK2,GRM7,NEFH,PCMT1,SEC61A2,ACER3,TCF7L2,KAT6B,STXBP4,VLDLR" MicroRNA hsa-miR-3911:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-13 6.91E-10 2.11E-13 1.95E-12 27 95 "ADCY5,CARNS1,CACNA1A,SLC22A6,TMEM184B,IGLON5,CREB5,ST18,DCAF8,TMEM130,DMTF1,MRPL37,WAC,CAMKK2,GPT2,IL1RAPL1,NKD1,MAP2,MAT2A,NOS1,SDK2,SATB1,NCDN,TPM4,ZNF28,ELFN1,DPYSL5" MicroRNA hsa-miR-1307-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-13 6.93E-10 2.12E-13 1.95E-12 44 240 "CDC14B,KIAA1614,FOXK1,MAP7,DIS3L,ZNF385A,HINFP,GNE,KRBA2,HEYL,OPTN,TUBD1,SLC43A2,MRPL37,SRARP,FGFR1,APOPT1,MSANTD4,NEK6,RAB40B,DDX19B,HMGB1,DOCK7,IL6R,LIMS1,ZNF655,EXOSC10,APTX,PTAFR,MTMR10,PNMA8A,SNX22,PEX26,ZNF430,SHANK2,ERC1,ZBTB43,DIP2A,KLHL7,ACSL6,VWC2,TPCN2,PCDHA6,GPR161" MicroRNA "CTCTAGA,MIR-526A:MSigDB" "CTCTAGA,MIR-526A:MSigDB" MSigDB 1.24E-13 6.99E-10 2.14E-13 1.97E-12 20 50 "SORCS1,ANK2,ADGRB3,BCL2L2,CS,FHL1,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,ZC3H12B,PIK3CD,ING3,KCNIP2,SS18,KLHL7,PUM2,SLC4A10" MicroRNA "CTCTAGA,MIR-526C:MSigDB" "CTCTAGA,MIR-526C:MSigDB" MSigDB 1.24E-13 6.99E-10 2.14E-13 1.97E-12 20 50 "SORCS1,ANK2,ADGRB3,BCL2L2,CS,FHL1,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,ZC3H12B,PIK3CD,ING3,KCNIP2,SS18,KLHL7,PUM2,SLC4A10" MicroRNA "CTCTAGA,MIR-518F:MSigDB" "CTCTAGA,MIR-518F:MSigDB" MSigDB 1.24E-13 6.99E-10 2.14E-13 1.97E-12 20 50 "SORCS1,ANK2,ADGRB3,BCL2L2,CS,FHL1,TBR1,JPH4,IL1RAPL1,KLF12,TJAP1,BRINP3,ZC3H12B,PIK3CD,ING3,KCNIP2,SS18,KLHL7,PUM2,SLC4A10" MicroRNA hsa-miR-4467:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.28E-13 7.18E-10 2.19E-13 2.02E-12 23 68 "PRX,PDXK,DNAH17,BRSK2,GPR37L1,CBARP,ELMSAN1,EIF4G1,MTSS1L,CPLX1,MSI1,NEUROD2,PKD1,FXYD1,PEG10,SSTR1,MAPK8IP3,ARC,WSCD1,CLASP1,FBXL16,NSD2,CELF4" MicroRNA hsa-miR-6878-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-13 7.27E-10 2.22E-13 2.04E-12 45 250 "PPFIA4,CDC14B,DDX3Y,CANX,FMNL3,CHRNB2,EPS15L1,SUMF2,BTF3L4,IP6K1,ELMSAN1,SGSM2,SEC16A,MRO,MTSS1L,NCKAP1,GLUL,MIER3,KCNK3,SAMD14,NDUFA5,GPR137C,GPR173,CCSER2,FTO,PLIN1,SDK2,TNPO2,PPARA,PTPA,PTPRE,RAB5B,SETD5,SOX6,SEPHS1,ATF7IP,CLSTN2,ZSCAN29,AJAP1,FBXW11,ZNF34,TPM2,WBP2,UBTF,HNRNPA3" MicroRNA hsa-miR-4692:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-13 7.71E-10 2.35E-13 2.17E-12 37 176 "ARHGDIA,DNAH17,ATP1B3,BTRC,ISPD,EVI5L,CS,PHYHIP,IGSF6,TMEM132C,PTK2B,FDFT1,SESN1,IRAK3,TNFAIP8L3,ZIC5,KCNJ11,NBL1,NRGN,TBC1D25,CDK18,RETREG2,QDPR,HSD11B1L,RMI1,SBF1,MYO18A,PEX26,TRIM67,NEK4,SLC37A2,FAM208A,TPM4,TRPS1,TSN,RPL7L1,AMZ1" MicroRNA hsa-miR-6804-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-13 8.28E-10 2.53E-13 2.33E-12 31 126 "PLEKHG5,TXNDC16,ARRB1,ASTN1,CANX,CDC25B,CACNA2D2,EPS15L1,SYT15,EN2,DOT1L,SEPT9,TNRC6A,GNAS,GRIN2D,NFIX,PKM,PLCD1,PLEC,RETREG2,TNPO2,PPP2R2B,PKIA,MORC4,GALNT10,SMTN,STX1A,TMEM151B,TPD52,SLC38A1,ACTR3B" MicroRNA hsa-miR-503-5p:Functional MTI Functional MTI miRTarbase 1.50E-13 8.42E-10 2.57E-13 2.37E-12 45 251 "TAOK1,TRMT9B,ANK3,CASK,DNAH17,MTMR3,FOXK1,CA8,CANX,CCNT1,LRWD1,DLGAP3,CLTC,SOCS5,TOMM20,YTHDC1,ELMSAN1,SEC16A,DMTF1,PLEKHA1,MRPL10,FGFR1,HNRNPK,MYO5A,OCRL,ANLN,PIK3R1,PSAT1,PPP2R5C,CNNM2,PTPRD,ZFHX4,TMEM100,RPL15,FBXW7,KIAA0895L,SALL1,SBF1,KANK1,DDHD2,ZMAT3,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-6780b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-13 8.84E-10 2.70E-13 2.48E-12 43 232 "TRMT9B,KIF6,ARRB2,TPP1,ZNF385A,PLEKHM1,DUSP9,APH1A,MRO,RTN3,GLUL,GPR26,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,OLR1,PFKFB2,CDK14,PKM,FXYD1,EPB41L4B,TNPO2,WBP1L,IQSEC3,MYH14,KIAA0895L,SBF1,DRAXIN,COPZ1,SHMT2,PKNOX2,WDTC1,UNC5B,POGZ,MPRIP,AHCYL2,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-4725-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-13 8.84E-10 2.70E-13 2.48E-12 43 232 "TRMT9B,KIF6,ARRB2,TPP1,ZNF385A,PLEKHM1,DUSP9,APH1A,MRO,RTN3,GLUL,GPR26,NXPH3,MIER3,SCIN,ZFYVE27,MAT2A,OLR1,PFKFB2,CDK14,PKM,FXYD1,EPB41L4B,TNPO2,WBP1L,IQSEC3,MYH14,KIAA0895L,SBF1,DRAXIN,COPZ1,SHMT2,PKNOX2,WDTC1,UNC5B,POGZ,MPRIP,AHCYL2,ASXL3,TUBB2A,BCL2L13,ZNF708,ITM2C" MicroRNA hsa-miR-6795-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-13 9.15E-10 2.79E-13 2.57E-12 27 96 "ACTN2,ASPA,ATP1A2,HCN2,NIPA1,PNKD,CYBB,SEPT9,GBX2,FAM107A,PADI2,SHISA6,KCNJ10,CTNNA3,RDX,GTDC1,SETD5,ZFP1,SMARCE1,ZHX3,NSFL1C,TMEM151B,THRA,C5orf64,ZNF24,URM1,PPP1R3F" MicroRNA hsa-miR-608:Functional MTI Functional MTI miRTarbase 1.67E-13 9.35E-10 2.85E-13 2.62E-12 39 195 "PNMA8B,KIAA1614,ARHGDIA,CDC42,CRLF1,DLGAP3,ZNF385A,IP6K1,PLEKHM1,SGSM2,ELN,MTSS1L,ANKRD13B,ANKFY1,GLI2,POLL,PRRC2B,CECR2,KCNK3,MDM4,MPP2,ZC3H12B,NKX2-2,OGDH,PKM,PLEC,EPN1,SPATA6,PACSIN1,PPARA,MAPK10,MYH14,KLHDC8A,FOXRED2,ATXN2,UNC5B,SEPT8,TPM3,UBTF" MicroRNA hsa-miR-6739-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.67E-13 9.39E-10 2.86E-13 2.64E-12 25 82 "SPOP,ARHGDIA,INSYN2B,C1orf52,USP6NL,YTHDC1,ST8SIA3,YAF2,ELAVL2,SEZ6,ERBB2,STAMBP,TNRC6A,ATOH8,NCKAP1L,IGF1,KSR2,PDE1B,SON,SOX1,DNAJC9,FAM200B,TNS1,TRPS1,UBE3A" MicroRNA hsa-miR-1299:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-13 9.55E-10 2.91E-13 2.68E-12 26 89 "BEND6,ATP1B3,DPY19L3,MYRF,CANX,CLCN3,TMEM184B,DCAF4,EPB41,TMEM151A,GNAS,NUDT21,CYP27C1,PRRX1,C1orf109,MYO18A,AMBRA1,R3HDM2,FAIM2,IQSEC2,ZC3H4,NACC2,TMPO,SSBP2,NDRG4,SLC30A4" MicroRNA hsa-miR-4514:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-13 1.11E-09 3.39E-13 3.12E-12 37 178 "ARHGDIA,DNAH17,ATP1B3,BTRC,ISPD,EVI5L,CS,PHYHIP,IGSF6,TMEM132C,PTK2B,FDFT1,SESN1,IRAK3,TNFAIP8L3,ZIC5,KCNJ11,NBL1,NRGN,TBC1D25,CDK18,RETREG2,QDPR,HSD11B1L,RMI1,SBF1,MYO18A,PEX26,TRIM67,NEK4,SLC37A2,FAM208A,TPM4,TRPS1,TSN,RPL7L1,AMZ1" MicroRNA hsa-miR-6083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.98E-13 1.11E-09 3.39E-13 3.12E-12 37 178 "GRAMD1B,NLGN4X,ZNF608,HACE1,SLC24A2,C4orf33,QKI,TBPL1,HINFP,MYADM,DGKG,PITPNC1,CDON,FARSB,FEM1B,NPTN,MSANTD4,PPARGC1A,TNRC6A,BACH2,DOCK7,LIFR,FGFBP3,CCDC80,PRIMA1,WDTC1,MYCBP2,PRRC2C,SYP,TMEM178B,AGTPBP1,SIK3,NR2C2,CADM1,ZBTB16,MAP3K12,ZXDA" MicroRNA hsa-miR-759:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-13 1.13E-09 3.42E-13 3.15E-12 38 187 "SLC24A4,KIAA1324,CAPRIN2,VXN,CCPG1,EPS15L1,COL9A2,SEC24C,FAM107B,E2F6,EDN1,C8orf37,RABEPK,ZNF549,KATNAL1,ATP13A4,ZNF234,GNAL,DDX19B,DOCK7,ZNF678,KCNN3,OLR1,GPR137C,STK32A,FOXRED2,SATB1,IL17RB,MAGI3,AMBRA1,SLC8A3,FAM126B,EMC1,TROVE2,GSE1,AP4E1,AMACR,TUBB2A" MicroRNA hsa-miR-630:Functional MTI Functional MTI miRTarbase 2.13E-13 1.20E-09 3.64E-13 3.35E-12 24 76 "BCL2L2,FOXK1,CPS1,JAKMIP2,MRO,EIF5,PLEKHA1,STARD3NL,DCTN4,FOXM1,LILRA2,GPR26,PTPRT,IL6R,LSAMP,CD200,PDGFRA,ATXN1,DIP2A,TLR4,RBFOX2,VLDLR,ZNF70,PAK5" MicroRNA hsa-miR-125b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-13 1.22E-09 3.70E-13 3.41E-12 29 112 "CSMD2,TXNDC16,ANK1,TNRC6C,ZNF555,DLGAP3,TOGARAM2,GREB1,NOS1AP,TM9SF4,TMTC1,PLEKHA1,JKAMP,MSANTD4,SESN1,SYTL4,ZNF713,NDUFS7,PTAFR,GTDC1,SBF1,CSRNP3,POGZ,DIP2A,ACSBG1,IQCE,USP22,NSD1,SLC38A1" MicroRNA hsa-miR-8079:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-13 1.22E-09 3.70E-13 3.41E-12 29 112 "AS3MT,GOLGA7B,SFMBT2,ARSE,PDE4DIP,MYADM,SUCO,APOPT1,MSANTD4,SRCAP,GRB10,RASSF8,HAS2,MAN2A2,LYPLAL1,CHST6,MYO5A,OCRL,ZNF426,GSTCD,ROBO1,CSRNP3,ANKRD36,CLUAP1,ZNF34,RICTOR,WIPF2,MPPE1,TMEM63C" MicroRNA hsa-miR-3919:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-13 1.22E-09 3.72E-13 3.42E-12 35 161 "INTS2,MTUS1,BCAS1,CDC14B,ARHGEF7,CLDN10,KIAA0513,G3BP2,TUBB4A,SGIP1,CELF1,MSANTD4,ATP8A2,COPS8,TNRC6A,GPM6B,KIAA1755,CREG2,SYT9,OPHN1,PDPK1,NLE1,RNASEL,SGK1,ZFP30,FAM126B,SON,PDZD2,MAPK8IP3,STX1A,TCF7L2,NACC2,MEAF6,SF1,WIPF2" MicroRNA hsa-miR-21-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-13 1.28E-09 3.89E-13 3.58E-12 25 83 "ZNF608,KIF6,GPAM,ARNTL,CALM1,CDC42,ELMO1,SH3GLB1,KMT5B,CELF1,ZNF546,L1CAM,SMAD1,MAT2A,NCAM2,GPR137C,UHRF1BP1,ZNF793,SALL1,SGK1,SON,SOX11,CLASP1,SF1,CERS6" MicroRNA hsa-miR-127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-13 1.29E-09 3.92E-13 3.61E-12 30 120 "ARID1A,DGKD,DST,SYNJ2,FOXK1,DGKI,SRSF11,FBXO7,SH3GLB1,ZBED3,NSG2,PCLO,NR3C1,MBP,SYT9,PCDH9,PKD1,SNX10,PLEC,POLG,KANSL1,ROGDI,KLHL11,RUFY2,SPP1,USP22,AMOT,MEAF6,ZNF225,STOX2" MicroRNA hsa-miR-4451:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-13 1.31E-09 3.97E-13 3.66E-12 31 128 "ZNF578,AQP6,SLC2A11,BACH1,BTF3L4,DNAL1,MTX3,DNAH9,MAMLD1,EIF1,TUBD1,EPS8,DISC1,POLL,TDRKH,DDX19B,MDM4,SLC11A2,MTRF1L,GDPD1,QDPR,ZYG11B,ARMH4,MAPKBP1,NSD1,TPD52,TPM3,TUBB2A,ZNF28,CSDE1,C12orf4" MicroRNA hsa-miR-33a-5p:Functional MTI Functional MTI miRTarbase 2.38E-13 1.34E-09 4.05E-13 3.73E-12 37 179 "RNF157,KCTD16,OSBPL6,SEMA7A,ZNF583,CRY2,CSNK1G3,SOCS5,TMEM170A,EDN1,EN2,RTN3,ACSL4,FER,VTI1B,HBS1L,MIER3,KCNK1,CNOT4,GPR137C,PSAT1,PPARA,PRKCB,MAPK8,PTHLH,BSDC1,PPP1R9A,ATF7IP,ZNF415,PALLD,ERBIN,SATB2,LRRC8A,TNS1,RUNDC3B,REEP1,RTN4" MicroRNA hsa-miR-7515:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-13 1.37E-09 4.15E-13 3.82E-12 34 153 "ELFN2,AK2,SEMA4G,ARRB2,HCN2,DCAF5,CA8,FRMPD4,DUSP9,APH1A,ING4,PRRC2B,RAPGEF1,NXPH3,MIER3,IDH3A,MAT2A,MDM4,SCAMP5,PABPC1L2A,CLDN11,EPB41L4B,PACSIN1,PTPA,PRRT2,ANKRD36,SP2,STX1A,ARL10,ZFP91,TPM2,WBP2,MEAF6,URM1" MicroRNA hsa-miR-4638-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.61E-13 1.47E-09 4.44E-13 4.09E-12 44 245 "KIDINS220,CDC14B,KIAA1614,FOXK1,MAP7,DIS3L,HINFP,FGFR1OP2,GNE,KRBA2,HEYL,OPTN,TUBD1,SLC43A2,MRPL37,SRARP,FGFR1,APOPT1,MSANTD4,RAB40B,DDX19B,HMGB1,IL6R,KCND3,LIMS1,ZNF655,EXOSC10,APTX,MTMR10,NWD1,PNMA8A,SNX22,PEX26,ZNF430,ERC1,ZBTB43,DIP2A,KLHL7,ACSL6,VWC2,TPCN2,PCDHA6,GPR161,ARL10" MicroRNA hsa-miR-548au-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-13 1.59E-09 4.81E-13 4.43E-12 27 98 "RNF150,PDXK,ATP1B3,ZNF582,BTRC,ZMYM4,FOXN3,PHF19,PITPNC1,ELMSAN1,APOPT1,MALT1,FICD,DDX19B,KCNJ11,MDM4,MKLN1,NWD1,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,TSN,TUBB2A,BCL2L13" MicroRNA hsa-miR-4801:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-13 1.59E-09 4.81E-13 4.43E-12 27 98 "ADCYAP1R1,LDHD,CACNA2D1,RAB3C,QKI,ACBD5,KIAA0513,FBXL5,CPEB2,NEU3,SESN1,DIDO1,ZIC5,ZNF678,SFXN5,THYN1,MYO6,NDUFA5,OLR1,P2RY1,PPP2R5E,ROBO2,SBF1,AJAP1,TJP1,TPM2,GAN" MicroRNA hsa-miR-7641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-13 1.59E-09 4.81E-13 4.43E-12 32 137 "ARID1A,PWWP2A,TAOK1,GOLGA7B,SLC7A14,DOCK11,AKAP6,RTTN,HINFP,SOCS5,PYGO1,CEP170,DRP2,GNE,KRBA2,HEYL,COQ7,IGSF6,UFM1,MYOZ2,IGF1,IL6R,MTMR10,UEVLD,SCN7A,HSPA4L,CHD9,DIP2A,ARL10,TMEFF2,USP1,SLC30A4" MicroRNA hsa-miR-6515-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.84E-13 1.60E-09 4.84E-13 4.45E-12 38 189 "GRAMD1B,SPOP,DGKD,GPR146,STOML1,PNKD,PITPNM3,UBXN2A,PLCXD3,GAPVD1,CENPL,C2CD2L,FCF1,ZNF391,SCML2,TMEM175,CELF1,NSG1,DKK3,GABRG2,PTGDR2,HMGB1,IBA57,MYBPC1,NOVA2,NPTX1,KSR2,PKIA,PTPRN2,ATXN1,EPN2,LIMCH1,PEG10,TMEM178B,CYB561A3,TRPC3,PRDM10,NUP214" MicroRNA hsa-miR-323-5p:PITA hsa-miR-323-5p:PITA_TOP PITA 2.95E-13 1.65E-09 5.01E-13 4.61E-12 24 77 "ELFN2,SPOP,DGKD,ATP1B3,CDH8,CNR1,CLIP3,GPR61,PSD2,KLF12,MIER3,MYLK2,NNAT,PSD,DPF2,ATXN1,SOX6,CLASP2,GANAB,SEMA4A,UNC5D,MTMR14,WIPF1,NAV3" MicroRNA hsa-miR-191:PITA hsa-miR-191:PITA_TOP PITA 2.95E-13 1.65E-09 5.01E-13 4.61E-12 24 77 "PITPNM2,ATP2B2,B4GALT6,PHC2,FRY,SIDT2,EMX2,GAP43,IL1RAPL1,MSI1,NPTX2,NRCAM,TMOD2,ZNF532,SAFB,SATB1,TET1,RIMS1,ZCCHC24,ELOVL4,HEY1,TJP1,DDHD1,MAP3K12" MicroRNA hsa-miR-151a-3p:TargetScan hsa-miR-151a-3p TargetScan 2.95E-13 1.65E-09 5.01E-13 4.61E-12 24 77 "ATM,ATP2A2,PLXNA4,PPP1R16B,ELMO1,CALN1,EFNA3,DLC1,CHL1,GABRB1,GHR,KLF12,PDE3A,FTO,CEP41,PKIA,FIGN,NPAS3,CLASP2,HHIP,NPL,NAV3,FXR1,GAN" MicroRNA hsa-miR-4270:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-13 1.66E-09 5.01E-13 4.61E-12 41 217 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ABI2,ERBB2,SCML2,GABRA5,RAPGEF1,ZNF496,SLC6A17,MDFI,COMMD5,NBL1,TBC1D25,PCSK2,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CAMSAP2,CLASP1,THRA,NACC2,TPD52L2,PPIL6,TMPRSS5,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA hsa-miR-6807-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.22E-13 1.81E-09 5.47E-13 5.04E-12 74 577 "ABCF1,SYN3,CLK4,NDRG3,SLC24A4,HECW2,AK2,TAOK1,KIF6,PHF12,AMER3,ATP1B3,DOCK11,RGS11,BCL2L2,FOXK1,CBFA2T2,CDR1,DIS3L,GPR37L1,JAM2,NRXN3,ACBD5,NCOR2,PPP1R16B,GAPVD1,DBT,RABGAP1L,MTX3,MRNIP,ZNF549,ANKMY1,KATNAL1,ZNF585B,CEP78,MSANTD4,FAXC,COPS8,GPR75,GNG4,ZBTB49,DDX19B,HMGB1,ZNF491,NKD1,IL6R,INPP5B,CLVS2,CYP27C1,ZNF680,CCDC80,NFIX,TBC1D25,PIK3CD,TMEM38A,FTO,TATDN3,MSANTD2,PGBD4,MAGI3,ATF7IP,FAM126B,CLUAP1,EMC1,SSTR2,INKA2,TAL1,AHCYL2,VWCE,ZFP91,ZNF70,EVI5,MPPE1,AP3B2" MicroRNA hsa-miR-6741-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-13 1.89E-09 5.72E-13 5.27E-12 43 237 "XKR4,CDC14B,KIAA1614,FOXK1,MAP7,CDH8,DIS3L,PCYT1B,HINFP,PITPNM3,FGFR1OP2,SMG7,GNE,KRBA2,HEYL,OPTN,EMX2,TUBD1,SLC43A2,SRARP,FGFR1,APOPT1,MSANTD4,RAB40B,GPT2,DDX19B,HMGB1,SHISA6,IL6R,LIMS1,ZNF655,EXOSC10,APTX,MTMR10,NWD1,PNMA8A,SNX22,DIP2A,KLHL7,ACSL6,TPCN2,PCDHA6,ARL10" MicroRNA hsa-miR-6754-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-13 1.94E-09 5.86E-13 5.40E-12 41 218 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ABI2,ERBB2,SCML2,GABRA5,RAPGEF1,ZNF496,SLC6A17,MDFI,COMMD5,NBL1,TBC1D25,PCSK2,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CAMSAP2,CLASP1,THRA,NACC2,TPD52L2,PPIL6,TMPRSS5,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA hsa-miR-3934-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-13 2.00E-09 6.05E-13 5.57E-12 47 277 "TMEM132B,TAOK1,PHF12,ARRB1,FOXK1,CACNB2,STOML1,SOCS5,FAM131B,GNE,MRNIP,BSCL2,WAC,TUBA1B,ZNF44,FAXC,POLL,KIF3A,MFSD2A,DDX19B,ATCAY,C2orf72,ZIC5,KCNN1,KCNN3,NRGN,P2RX7,TMOD2,PIK3C2A,PIGG,NWD1,PRRT2,DCUN1D2,KLHDC8A,HUNK,FOXRED2,HSPA4L,ZNF430,SLC15A2,CLUAP1,ZBTB43,DIP2A,STAC2,GPRIN3,ZNF708,MPPE1,FXR1" MicroRNA hsa-miR-503:mirSVR_highEffct hsa-miR-503:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.62E-13 2.04E-09 6.15E-13 5.66E-12 34 155 "ACHE,ANK3,MARK4,KSR1,TMEM155,FEZ1,DCAF8,E2F5,TSPAN5,FCGR1A,STRADA,DACH2,SDCBP2,RNF165,FRMD3,KCND3,PAXBP1,MSR1,MYO7A,NDP,RBBP6,TMEM100,SEC14L1,KIF21A,UNC80,ZNF423,DBNDD2,SEPT3,DDHD2,TCF7L2,TPM1,RICTOR,MKRN3,TTC7A" MicroRNA hsa-miR-99b*:mirSVR_highEffct hsa-miR-99b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.65E-13 2.05E-09 6.18E-13 5.69E-12 31 130 "KCTD16,TTLL9,ARHGEF7,RUNX1T1,CREM,FEZ2,HS3ST2,MED12,MEX3B,EFCAB2,MSANTD4,OGA,ZNF276,TCERG1,NCKAP1L,SMAP1,KCNQ3,MYBPC1,PKN2,TMEM255A,RBBP6,ZYG11B,ATXN7,CNKSR2,SLC1A7,ZC3H4,TCF7L2,TIAM1,TMPO,DCBLD1,PRTFDC1" MicroRNA hsa-miR-133a-3p:Functional MTI Functional MTI miRTarbase 3.65E-13 2.05E-09 6.18E-13 5.69E-12 31 130 "SNX30,HCN2,CDK5R1,CDC42,ZFP28,HAPLN1,IP6K1,EGFR,ERBB2,PDLIM5,RFFL,IGF1,RBPJ,IBA57,ITPKB,KCNH2,SESN3,PDE1A,PKM,FAM120C,ZMAT4,PRRT2,RGS3,EMID1,MEG3,BCAN,NCDN,ZEB1,TPM1,TPM3,NR2C2" MicroRNA hsa-miR-1913:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-13 2.05E-09 6.18E-13 5.69E-12 31 130 "LRFN1,TOGARAM2,CPS1,YTHDC1,G3BP2,BSCL2,MRPL37,SEC24B,SEC23B,KIAA1841,FAXC,SRCAP,MFSD2A,FAM107A,GPR45,HMGB1,MAP4,MBD1,MDGA1,KCNK10,ZDHHC8,CAMKV,PIGG,KLHL11,ATXN1,HSPA4L,STAC2,GSE1,WWC1,KIAA0930,NACC2" MicroRNA hsa-miR-4731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-13 2.08E-09 6.26E-13 5.77E-12 27 99 "ADCYAP1R1,LDHD,CACNA2D1,RAB3C,QKI,ACBD5,KIAA0513,FBXL5,CPEB2,NEU3,SESN1,DIDO1,ZIC5,ZNF678,SFXN5,THYN1,MYO6,NDUFA5,OLR1,P2RY1,PPP2R5E,ROBO2,SBF1,AJAP1,TJP1,TPM2,GAN" MicroRNA hsa-miR-145-5p:Functional MTI Functional MTI miRTarbase 3.91E-13 2.20E-09 6.63E-13 6.10E-12 43 238 "NDRG2,ADD3,SMIM17,MYRF,THSD7A,CDH2,ZNF445,ZFYVE9,UBXN2A,CTNND1,PLEKHM1,NR1D2,APH1A,EGFR,ERBB4,EID2B,ZNF678,MEST,SAMD5,CCDC80,MYO5A,MYO6,ZNF426,PNMA3,PSAT1,PPP3CA,TUG1,UBR7,ALG9,ROBO2,RTKN,CSRNP3,KIF21A,CPEB4,SOX2,SOX11,CLSTN2,ANKRD28,UNC5D,MTMR14,TNR,TPM3,PRDM2" MicroRNA hsa-miR-411-5p.1:TargetScan hsa-miR-411-5p.1 TargetScan 4.02E-13 2.26E-09 6.81E-13 6.27E-12 26 92 "ADORA1,CACNB4,RUNX1T1,CCNT1,CDH2,RAB3C,KIAA1549L,AKAP5,PUM1,FBXL5,KLHL3,EIF4G2,ERBB4,CAMSAP1,CAMKK2,LNX1,CD200,LRP12,RORB,FNIP1,IL17RB,PREX2,EPC1,CLIP2,ELFN1,NAV3" MicroRNA hsa-miR-6796-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-13 2.26E-09 6.81E-13 6.27E-12 26 92 "XKR4,CDC14B,SLC7A14,RUNX1T1,KIAA0408,KIAA0319,ABI2,FGFR3,ZBED3,MSANTD4,GSTM5,LIMS1,MAP4,MMP16,PAX6,EPB41L4B,AMBRA1,MBD5,ZNF621,ITPRID2,WWC1,ARL10,ERCC6L2,PARD3,CCDC14,WIPF2" MicroRNA hsa-miR-4441:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.04E-13 2.27E-09 6.84E-13 6.30E-12 41 219 "OGT,ARHGDIA,IPCEF1,TM9SF4,IP6K1,SPATA2,ELMSAN1,SV2B,DUSP9,ABI2,ERBB2,SCML2,GABRA5,RAPGEF1,ZNF496,SLC6A17,MDFI,COMMD5,NBL1,TBC1D25,PCSK2,PKD1,KCTD15,SLC25A23,RETREG2,RNH1,SOX11,ERC1,DDN,CAMSAP2,CLASP1,THRA,NACC2,TPD52L2,PPIL6,TMPRSS5,BCL2L13,TSPAN11,SLC30A3,GDPD5,RNF146" MicroRNA hsa-miR-769-5p:Non-Functional MTI Non-Functional MTI miRTarbase 4.33E-13 2.43E-09 7.32E-13 6.74E-12 42 229 "KIAA1211,PDXK,BACH1,LRBA,LRWD1,TAOK2,USP6NL,LONRF1,INTS1,MRO,PLEKHA1,SCML2,SCARA3,FAM49B,GART,KIAA1841,TCERG1,PRUNE2,ATF7,ZNF678,PABPC1L2A,NELL2,ZDHHC8,PKM,PEX2,CEP97,KLHL11,ZC3H14,SCP2,MAGI3,URGCP,PEX26,RAB3GAP1,FAM126B,ZSCAN29,GSE1,SLC37A2,ATP11A,AHCYL2,RGMB,SPIRE1,PARP6" MicroRNA hsa-miR-493-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-13 2.53E-09 7.62E-13 7.02E-12 29 115 "PWWP2A,USP28,ARHGAP5,HIP1R,MAP7,USP2,TBRG4,SOCS5,TBC1D5,WAC,SARAF,GRIK3,ZDHHC15,L1CAM,OLR1,PCSK1,PDPK1,CDK14,C12orf49,FNIP1,TRA2B,RPH3A,SP4,PRRC2C,SYT4,AGTPBP1,TRIM2,SLC44A1,EVI5" MicroRNA hsa-miR-4762-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-13 2.53E-09 7.62E-13 7.02E-12 29 115 "ADD2,CFL2,FOXN3,OSBPL3,CST3,KIAA0513,RUSC2,SH3GLB1,C3orf18,CAMSAP1,MALT1,RAB30,POLL,L1CAM,ARHGAP12,LSAMP,NPTX2,NUCB1,KANSL1,PEX2,PGBD4,FNBP1,KIF1B,FAM181B,NSD2,ZNF74,REEP1,WNK3,FXR1" MicroRNA hsa-miR-146b-3p:PITA hsa-miR-146b-3p:PITA_TOP PITA 4.51E-13 2.53E-09 7.62E-13 7.02E-12 29 115 "DYNLL1,ADGRB1,HAP1,FMNL3,CNTNAP2,DBN1,DYNC1I1,PPP1R1B,SGIP1,BRSK1,GK,LINGO1,MAT2A,NRCAM,RETREG2,NXPH1,TMEM260,OXR1,PPP4R3A,CPEB4,RIMS1,DDN,ST5,ADGRL3,THRA,ZFP91,RBFOX2,NAV3,VANGL2" MicroRNA hsa-miR-6794-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.68E-13 2.63E-09 7.91E-13 7.28E-12 35 165 "RNF157,SORCS2,EVI5L,DUSP9,EIF4G1,EPB41L1,WAC,AFF2,CELF1,GLUL,MDM4,MPP2,SESN3,NBL1,NDUFA5,NEUROD2,CCSER2,TNPO2,PTPA,BDNF-AS,IQSEC3,PRRT2,SETD5,EMID1,SARS,SHMT2,SON,WDTC1,NMNAT2,ERC1,SSTR1,ZNF34,HHIP,THRA,ITM2C" MicroRNA hsa-miR-548f-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.68E-13 2.63E-09 7.91E-13 7.28E-12 35 165 "XKR4,PTCHD1,PHF12,APP,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,ABI2,STARD3NL,SCML2,SUCO,RNPS1,GRK4,HMGB1,SCIN,KLRC3,DDR2,TNPO2,CRLS1,KANSL1,GRAMD1C,DIRAS2,TMLHE,CLUAP1,TUBB2A,PITPNB,EML6,SMARCAD1,WNK1,NHSL1" MicroRNA hsa-miR-4651:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.76E-13 2.68E-09 8.04E-13 7.41E-12 38 192 "PNMA8B,KIAA1614,ARHGDIA,CRLF1,DLGAP3,ZNF385A,IP6K1,PLEKHM1,SGSM2,ELN,MTSS1L,ANKRD13B,ANKFY1,GLI2,POLL,PRRC2B,CECR2,KCNK3,MDM4,MPP2,ZC3H12B,NKX2-2,OGDH,PKM,PLEC,EPN1,SPATA6,PACSIN1,PPARA,MAPK10,MYH14,KLHDC8A,FOXRED2,ATXN2,UNC5B,SEPT8,TPM3,UBTF" MicroRNA hsa-miR-30e-3p:Functional MTI Functional MTI miRTarbase 4.83E-13 2.71E-09 8.15E-13 7.50E-12 36 174 "CDK13,CACNA1E,ENTPD4,MAML1,YTHDC1,FAM107B,DYRK1A,EIF1,CAMSAP1,NPTN,GABRA2,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,MDM4,KCTD6,NUCB1,PCSK2,SERPINE2,EPB41L4B,PPP2R2B,SH3TC2,CCDC25,SCP2,GALNT10,CLSTN1,SLC1A2,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2,FAM47E" MicroRNA hsa-miR-34c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.83E-13 2.71E-09 8.15E-13 7.50E-12 36 174 "PDXK,ZMYM4,EVI5L,FOXN3,PHF19,CTIF,MRNIP,APOPT1,GABRA3,POLL,GRM7,FICD,DDX19B,HSP90AA1,IL6R,MAP4,MAPT,MDM4,MKLN1,GIT1,MYCN,NEUROD2,CNOT4,PDGFRA,COPZ1,CPEB3,SNCA,SOX2,PEG10,SATB2,TPCN2,SLC35G2,TJP1,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-1909-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.85E-13 2.72E-09 8.18E-13 7.54E-12 37 183 "ELFN2,RNF157,SEMA7A,HCN2,CANX,HEYL,IRAK4,WAC,TUBB4A,DLC1,PDLIM5,CELF1,TMEM151A,GFER,C5orf24,KCNK3,MSI1,PKD1,PLEC,SLC25A23,PACSIN1,TNPO2,POLR2F,NCR3LG1,TMEM145,RAB5B,SARS,HES6,SP2,NFASC,MPRIP,CLASP1,ASXL3,ZFP91,GDPD5,ITM2C,HNRNPA3" MicroRNA hsa-miR-137:Non-Functional MTI Non-Functional MTI miRTarbase 4.91E-13 2.76E-09 8.28E-13 7.63E-12 33 148 "SERPINA3,FMNL2,USP28,BMP7,FOXK1,CDC42,DCLK1,DBN1,ZNF804A,ZC3H11A,CALN1,E2F6,EGFR,EIF1,COQ7,NR3C1,KLF12,ZDHHC15,ZNF678,KIT,SFXN5,MITF,MSI1,MED1,SNRK,RASGRF1,FNIP1,LIMCH1,ITPRID2,RFTN2,ZNF24,LYPD6,XKR7" MicroRNA hsa-miR-548d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.41E-13 3.04E-09 9.12E-13 8.40E-12 39 202 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,PPARA,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,ZMYND8,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-611:mirSVR_highEffct hsa-miR-611:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.54E-13 3.11E-09 9.33E-13 8.60E-12 24 79 "DDX3Y,CARMIL3,DNM1L,APH1A,CLVS1,SEMA6C,CELF1,DACH2,STARD3,ELOVL5,SMAP1,PCSK5,NLGN3,MTRF1L,TTC13,GTDC1,C11orf87,VAMP1,MTCL1,RIMBP2,C9orf85,TRPS1,OSBP2,SHD" MicroRNA hsa-miR-548ar-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-13 3.17E-09 9.51E-13 8.76E-12 35 166 "XKR4,PTCHD1,PHF12,APP,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,ABI2,STARD3NL,SCML2,SUCO,RNPS1,GRK4,HMGB1,SCIN,KLRC3,DDR2,TNPO2,CRLS1,KANSL1,GRAMD1C,DIRAS2,TMLHE,CLUAP1,TUBB2A,PITPNB,EML6,SMARCAD1,WNK1,NHSL1" MicroRNA hsa-miR-548e-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.64E-13 3.17E-09 9.51E-13 8.76E-12 35 166 "XKR4,PTCHD1,PHF12,APP,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,ABI2,STARD3NL,SCML2,SUCO,RNPS1,GRK4,HMGB1,SCIN,KLRC3,DDR2,TNPO2,CRLS1,KANSL1,GRAMD1C,DIRAS2,TMLHE,CLUAP1,TUBB2A,PITPNB,EML6,SMARCAD1,WNK1,NHSL1" MicroRNA hsa-miR-4483:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.65E-13 3.18E-09 9.52E-13 8.77E-12 31 132 "TAOK1,ARHGDIA,BCL7A,ZNF445,CSNK1E,PHF19,SIRPA,ABI2,PLEKHA1,ELN,MTSS1L,ANKFY1,CRCP,RNPS1,NFIX,NUCB1,OGDH,PLEC,PACSIN1,SKOR1,RAB5B,CEP97,PRRT2,SETD5,C12orf49,RMI1,MAGI3,TPCN2,TPM3,UBTF,SLC38A1" MicroRNA hsa-miR-3529-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.72E-13 3.21E-09 9.63E-13 8.87E-12 29 116 "CDC14B,MTMR9,SPAG9,FAM169A,SPATA2,MTX3,RAB39B,DNAJB6,FCF1,GABRA4,WASF3,FREM1,IBA57,ZNF678,MDM4,MKLN1,NCAM2,FIGN,FBXW7,SEMA6D,HSPA4L,SON,SOX5,MPRIP,SYPL1,TMEM136,TPCN2,GORASP1,SPATA13" MicroRNA hsa-miR-4292:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-13 3.26E-09 9.76E-13 8.99E-12 30 124 "NIPA1,ZNF445,CHRNB2,EPS15L1,UBXN2A,IP6K1,EIF5,IRAK4,ANKMY1,CELF1,SEPT9,GPR26,ITPKB,MAT2A,BEST3,PKD1,TNPO2,MTMR10,IQSEC3,PRRT2,RIMKLA,HES6,PEX26,NCDN,DIP2A,FAM168A,EXOC7,VAV2,XKR7,KAT6A" MicroRNA hsa-miR-615-5p:PITA hsa-miR-615-5p:PITA_TOP PITA 6.08E-13 3.42E-09 1.02E-12 9.43E-12 22 66 "SEMA6A,CDK5R2,CABP1,CLIP3,RGS6,RIMS4,DNAJC6,DMPK,APH1A,AGAP2,SYT3,GGT7,SCRT2,CAMK2N2,MEF2C,MEIS2,NCAM1,NFIX,PPP2R5C,PPP5C,MAPK10,FBXL16" MicroRNA hsa-miR-576-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-13 3.52E-09 1.05E-12 9.69E-12 27 101 "FZD9,ABCD2,KIAA1614,PTBP2,CRY2,SUCO,ANKFY1,PNMA2,SARAF,NCKAP1,GCK,ZHX1,HNF4G,NEGR1,IGF1,MBNL1,KITLG,NEUROD1,NPTX2,PKM,FAM216A,TET1,SOX1,AGTPBP1,RGMB,KAT6A,DPF3" MicroRNA hsa-miR-644:PITA hsa-miR-644:PITA_TOP PITA 6.26E-13 3.52E-09 1.05E-12 9.69E-12 27 101 "NLGN4X,ATP1A1,BCL2L2,MICAL2,DLG2,DMTF1,EPB41L2,SYNCRIP,FOXO3,TMEM151A,BRPF3,TNRC6A,GRIN2D,SMAP1,NEFH,NF1,GPR88,GNG2,MINDY2,ROBO2,ATXN1,SCN2A,STAC2,TCF4,TPM1,NR2C2,NAV3" MicroRNA hsa-miR-636:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-13 3.52E-09 1.05E-12 9.69E-12 27 101 "ELFN2,RNF157,SORCS2,OSBPL8,CCDC74A,IFFO1,DCAF4,KIAA0513,BLOC1S6,FAM198B,SRRM4,TMEM25,HECTD2,LRP12,PRKACB,CNNM2,RAD51D,SLC25A36,ROBO1,GLDN,ZNF354C,SARS,SATB1,MPRIP,TPD52,RPL7L1,HNRNPA3" MicroRNA hsa-miR-1224-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.26E-13 3.52E-09 1.05E-12 9.70E-12 45 261 "AS3MT,MTA3,AMER3,CACNA1A,CACNA1E,ZBED1,GAPVD1,RIPOR2,TOMM20,RABGAP1L,ABCC5,ABI2,SORBS3,ELAVL3,TNK2,MRPL37,FABP7,ANKFY1,ST6GALNAC3,GABRB1,FAXC,SRCAP,KIF3A,HAS2,ATCAY,KCNJ4,MAN2A2,CD200,TMOD2,PIK3C2A,ZNF426,PSAT1,KLHL11,GSTCD,KIF21A,FAM126B,ZCCHC24,CLUAP1,STAC2,TCF12,NSD1,ZNF34,ZNF708,MVB12B,HNRNPA3" MicroRNA hsa-miR-4716-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.79E-13 3.82E-09 1.14E-12 1.05E-11 35 167 "RNF157,SORCS2,EVI5L,DUSP9,EIF4G1,EPB41L1,WAC,AFF2,CELF1,GLUL,MDM4,MPP2,SESN3,NBL1,NDUFA5,NEUROD2,CCSER2,TNPO2,PTPA,BDNF-AS,IQSEC3,PRRT2,SETD5,EMID1,SARS,SHMT2,SON,WDTC1,NMNAT2,ERC1,SSTR1,ZNF34,HHIP,THRA,ITM2C" MicroRNA hsa-miR-8072:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-13 3.92E-09 1.17E-12 1.08E-11 20 54 "PDZD4,PRX,DNAH17,CACNA1B,BRSK2,CBARP,ELMSAN1,MTSS1L,CPLX1,MSI1,FXYD1,NMNAT2,PEG10,MAPK8IP3,ARC,WSCD1,CLASP1,VGF,CLIP2,CELF4" MicroRNA hsa-miR-3960:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-13 3.92E-09 1.17E-12 1.08E-11 20 54 "PDZD4,PRX,DNAH17,CACNA1B,BRSK2,CBARP,ELMSAN1,MTSS1L,CPLX1,MSI1,FXYD1,NMNAT2,PEG10,MAPK8IP3,ARC,WSCD1,CLASP1,VGF,CLIP2,CELF4" MicroRNA hsa-miR-299-3p:TargetScan hsa-miR-299-3p TargetScan 6.99E-13 3.93E-09 1.17E-12 1.08E-11 26 94 "ADD1,GRAMD1B,MARCH3,RUNX1T1,AIFM1,DLGAP3,IGLON5,KIAA0087,PLEKHO1,CACNG2,PRAM1,KAT7,IGF1,KNDC1,ITGAV,PAXBP1,GIT1,MSI1,GNG2,CSRNP3,ATXN2,HECW1,CAMTA2,AJAP1,EXOC7,MAP3K12" MicroRNA hsa-miR-6748-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.08E-13 3.98E-09 1.19E-12 1.09E-11 23 73 "DPY19L3,FMNL3,CCNT1,PITPNM3,TM9SF4,C2CD2L,TOM1,SORBS3,POLL,GRIK3,SYNPO,HPR,MAP4,MEIS1,JAKMIP3,N6AMT1,PALM,SCN2B,SMARCC2,ACSBG1,PCDHA6,SIGLEC10,WIPF2" MicroRNA hsa-miR-668-3p:TargetScan hsa-miR-668-3p TargetScan 7.26E-13 4.08E-09 1.22E-12 1.12E-11 30 125 "KCTD16,CDK13,MTMR3,MMD2,CAMK2G,CANX,CDH2,DNAJB5,FHL5,RCHY1,KBTBD11,PHF20L1,EMX2,FAXC,KLF12,NEGR1,IL6ST,ITPKB,MAPT,KITLG,NFYA,CNOT4,PAX6,PDE3B,PRRX1,MED1,PTPRG,SCN2B,ACSBG1,FGD4" MicroRNA hsa-miR-200a-3p:Functional MTI Functional MTI miRTarbase 7.32E-13 4.11E-09 1.23E-12 1.13E-11 33 150 "OGT,SPAG9,SEPT7,KIAA1549L,QKI,RASSF2,ZEB2,G3BP2,EGFR,ELAVL2,DLC1,CELF1,WASF3,MALT1,RAB30,KLF12,HMGB1,IPO5,MDM4,PCDH8,PTPRD,WDR37,ELMO2,ZNF621,TROVE2,ERBIN,SEPT8,ZEB1,DICER1,ZFPM2,ZMAT3,CLDND1,MFF" MicroRNA "GGCAGTG,MIR-324-3P:MSigDB" "GGCAGTG,MIR-324-3P:MSigDB" MSigDB 7.46E-13 4.19E-09 1.25E-12 1.15E-11 25 87 "SORCS1,PHF12,CHRD,CDC27,FOXN3,RIMS3,SRGAP3,G3BP2,DMTF1,EDNRA,EIF4G1,ING4,CIT,MBP,MEIS1,GIT1,SEMA5B,ZNF655,PRKACB,PBRM1,SFPQ,SHC4,ST3GAL3,SHANK2,FXR1" MicroRNA hsa-miR-4434:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-13 4.21E-09 1.26E-12 1.16E-11 39 204 "TRMT9B,CDC14B,CANX,FMNL3,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,EN2,KIAA1958,GRK4,BACH2,IDH3A,KCND1,KCNH2,MAP2,CCDC80,SAMD14,GPR137C,GPR173,SPATA6,TNPO2,PTPA,UHRF1BP1,SLC25A36,CLSTN2,ASTN2,FBXW11,AHCYL2,ZNF34,ZFP91,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-5703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-13 4.21E-09 1.26E-12 1.16E-11 39 204 "TRMT9B,CDC14B,CANX,FMNL3,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,EN2,KIAA1958,GRK4,BACH2,IDH3A,KCND1,KCNH2,MAP2,CCDC80,SAMD14,GPR137C,GPR173,SPATA6,TNPO2,PTPA,UHRF1BP1,SLC25A36,CLSTN2,ASTN2,FBXW11,AHCYL2,ZNF34,ZFP91,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-4273:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.53E-13 4.23E-09 1.26E-12 1.16E-11 24 80 "SPOP,FOXK1,C1orf52,BTF3L4,USP6NL,TOMM20,YTHDC1,ST8SIA3,YAF2,SH3GLB1,SEZ6,ERBB2,CACNG2,STAMBP,TUBGCP4,TNRC6A,ATOH8,NCKAP1L,IGF1,PDE1B,ZNF793,SOX1,DNAJC9,TRPS1" MicroRNA hsa-miR-3187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.89E-13 4.43E-09 1.32E-12 1.22E-11 42 233 "CARNS1,GOLGA7B,C6orf89,PDXK,ATP1A2,RAB3C,AKAP6,LRIG1,CSNK1E,MYADM,FGFR1OP2,KIAA0586,DBT,BLOC1S6,RABGAP1L,SIDT2,ABI2,COQ7,TRMO,CRCP,DDX19B,ATCAY,ZNF678,CYP27C1,DBNL,MYO6,OPHN1,PKM,SGSM1,PTGR2,RMI1,PEX26,FAM126B,KIF1B,LHPP,SSTR2,ALG1,WWC1,AGTPBP1,TUBB2A,ZNF70,GAN" MicroRNA hsa-miR-4516:Functional MTI Functional MTI miRTarbase 8.80E-13 4.94E-09 1.47E-12 1.36E-11 39 205 "TRMT9B,CDC14B,CANX,FMNL3,CCNT1,NSL1,CRMP1,SIPA1L1,PDE4DIP,UBXN2A,DUSP9,PHC2,ING4,EN2,KIAA1958,GRK4,BACH2,IDH3A,KCND1,KCNH2,MAP2,CCDC80,SAMD14,GPR137C,GPR173,SPATA6,TNPO2,PTPA,UHRF1BP1,SLC25A36,CLSTN2,ASTN2,FBXW11,AHCYL2,ZNF34,ZFP91,TPM2,RPRM,ZFAND5" MicroRNA hsa-miR-220a:mirSVR_highEffct hsa-miR-220a:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.13E-13 5.13E-09 1.53E-12 1.41E-11 29 118 "CSMD2,KLHL32,PWWP2A,CACNA1D,CACNA1E,DDR1,CACNA2D1,CACNA2D2,DNM1,ZNF589,GLI2,GNAO1,ZBTB49,IL6ST,OLFM3,KCNC1,ZFYVE27,PRKCZ,PSMD13,PTPRN2,KANSL3,CPEB4,KIF1B,NXT2,COBL,TPCN2,C9orf85,TRIO,KAT6A" MicroRNA hsa-miR-5093:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.13E-13 5.13E-09 1.53E-12 1.41E-11 29 118 "OGT,APP,WASF1,CANX,ISPD,CBS,KIAA0408,SUCO,GPT2,ZIC5,TJAP1,AFF1,GPR137C,LRP12,EPB41L4B,TNPO2,PPP3CB,CNNM2,C1orf109,PGBD4,ATXN7,HSPA4L,LHPP,ZSCAN29,TBCEL,ZNF34,WNT7A,ZNF28,HNRNPA3" MicroRNA hsa-miR-661:Functional MTI Functional MTI miRTarbase 9.15E-13 5.14E-09 1.53E-12 1.41E-11 63 459 "CLK4,SLC24A4,HACE1,TXNDC16,KIF6,AQP6,ARHGDIA,ZNF555,SLC16A4,SUSD5,SOCS5,UBXN2A,GAPVD1,CENPL,RUSC2,KLHL3,SGSM2,MTX3,EIF5,MTSS1L,PCYOX1,ATP13A4,ANKFY1,TRMO,GPR153,FUT9,STARD10,CRCP,GPR75,NXPH3,DDX19B,KCNN3,CHST6,MDM4,NKX2-2,SLC11A2,OLR1,TATDN3,STK32A,PEX2,CEP97,KLHL11,ZNF331,IL17RB,MAGI3,EMC1,LHFPL4,MCF2L2,SSTR2,INKA2,ADAMTS17,C3orf70,AHCYL2,PARD3,PPIL6,SSBP2,ZNF610,UBC,RPL7L1,USP1,TBC1D15,TRIM16L,GAN" MicroRNA hsa-miR-215:PITA hsa-miR-215:PITA_TOP PITA 9.16E-13 5.15E-09 1.53E-12 1.41E-11 26 95 "SDE2,CSMD3,PCDH19,ALCAM,PKP4,NIPBL,CREB5,DBT,ZEB2,CDON,DYRK1A,KHDRBS3,SPIN1,GPR22,LPAR4,ARHGAP19,PCDH9,SCN3A,NKAIN2,ADGRL3,WASHC4,DICER1,CADM1,FAM155A,SMARCAD1,WNK1" MicroRNA hsa-miR-192:PITA hsa-miR-192:PITA_TOP PITA 9.16E-13 5.15E-09 1.53E-12 1.41E-11 26 95 "SDE2,CSMD3,PCDH19,ALCAM,PKP4,NIPBL,CREB5,DBT,ZEB2,CDON,DYRK1A,KHDRBS3,SPIN1,GPR22,LPAR4,ARHGAP19,PCDH9,SCN3A,NKAIN2,ADGRL3,WASHC4,DICER1,CADM1,FAM155A,SMARCAD1,WNK1" MicroRNA hsa-miR-548a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-13 5.50E-09 1.64E-12 1.51E-11 35 169 "XKR4,PTCHD1,PHF12,APP,ARNTL,ATP2A2,LDHD,ZNF555,CALM1,ISPD,CLOCK,ENTPD4,ABI2,STARD3NL,SCML2,SUCO,RNPS1,GRK4,HMGB1,SCIN,KLRC3,DDR2,TNPO2,CRLS1,KANSL1,GRAMD1C,DIRAS2,TMLHE,CLUAP1,TUBB2A,PITPNB,EML6,SMARCAD1,WNK1,NHSL1" MicroRNA hsa-miR-1273f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.87E-13 5.54E-09 1.65E-12 1.52E-11 48 295 "SLC25A25,TMEM132B,MTA3,SEMA7A,C6orf89,CACNG1,CDC25B,COL9A2,KIAA0586,JAKMIP2,FARSB,PLEKHA1,C8orf37,EPB41L1,EPS8,C1orf61,TRAF3IP2,NCKAP1,FAXC,GLUL,POLL,PRRC2B,KCNJ3,GPR155,NOS1,PAK3,ZNF426,PPP2R5E,GDPD1,CEP97,ELP2,PTGR2,HSD11B1L,SCN2B,ELMOD1,FAM102A,NUBPL,FAM126B,CLUAP1,ALG1,KIAA0930,TPM3,SSBP2,TUBB2A,RPL7L1,LAT2,ZNF708,STOX2" MicroRNA hsa-miR-588:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-12 5.72E-09 1.70E-12 1.57E-11 41 225 "TAOK1,GOLGA7B,C6orf89,PDXK,ATP1A2,RAB3C,AKAP6,LRIG1,CSNK1E,MYADM,FGFR1OP2,KIAA0586,DBT,BLOC1S6,RABGAP1L,SIDT2,COQ7,TRMO,CRCP,IL1RAPL1,DDX19B,ATCAY,ZNF678,CYP27C1,MYO6,FBXW7,SGSM1,PTGR2,SATB1,PEX26,FAM126B,KIF21B,KIF1B,LHPP,SSTR2,ALG1,WWC1,AGTPBP1,ZNF70,URM1,GAN" MicroRNA hsa-miR-202-3p:Functional MTI Functional MTI miRTarbase 1.03E-12 5.80E-09 1.73E-12 1.59E-11 39 206 "SDE2,FZD9,ANK1,IGDCC4,BACH1,ARHGAP22,E2F6,EDN1,PLEKHO1,TOMM40L,CELF1,SALL3,POLL,FUT10,HAS2,MIER3,IL6R,MDM4,THYN1,MYCN,NAP1L1,NUCB2,OPRL1,USP47,RDX,FIGN,ATXN2,SOX6,FNDC3A,PEG10,MCF2L2,TROVE2,FNDC9,SYT1,KIAA0930,SLC19A3,TGFBR3,CBX5,RBFOX2" MicroRNA hsa-miR-520f-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-12 5.87E-09 1.74E-12 1.61E-11 27 103 "RNF157,SORCS2,OSBPL8,CAPRIN2,BACH1,CAMK2A,PRC1,IFFO1,IGDCC3,ZNF385A,GREB1,KIAA0513,FEM1B,MSANTD4,MALT1,PTGDR2,IL6ST,KCNB1,LRP12,PRKACB,SLC22A23,RAD51D,SON,TPD52,RGMB,NR2C2,WIPF2" MicroRNA hsa-miR-1293:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-12 6.03E-09 1.79E-12 1.65E-11 31 135 "TAOK1,ARHGDIA,BCL7A,ZNF445,CSNK1E,PHF19,SIRPA,ABI2,PLEKHA1,ELN,MTSS1L,ANKFY1,CRCP,RNPS1,NFIX,NUCB1,OGDH,PLEC,PACSIN1,SKOR1,RAB5B,CEP97,PRRT2,SETD5,C12orf49,RMI1,MAGI3,TPCN2,TPM3,UBTF,SLC38A1" MicroRNA hsa-miR-6791-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-12 6.34E-09 1.88E-12 1.74E-11 30 127 "NIPA1,ZNF445,CHRNB2,EPS15L1,UBXN2A,IP6K1,EIF5,IRAK4,ANKMY1,CELF1,SEPT9,GPR26,ITPKB,MAT2A,BEST3,PKD1,TNPO2,MTMR10,IQSEC3,PRRT2,RIMKLA,HES6,PEX26,NCDN,DIP2A,FAM168A,EXOC7,VAV2,XKR7,KAT6A" MicroRNA hsa-miR-126-5p:Functional MTI Functional MTI miRTarbase 1.15E-12 6.45E-09 1.92E-12 1.77E-11 29 119 "SEMA7A,SRSF11,CSNK1G3,LIN54,SLC12A6,FOXO3,FYB1,GABRA4,GATM,GRIK5,NR3C1,IL6R,MYCN,NPTX1,SNX10,PSAT1,MAPK8,SETD5,TMEM100,CSRNP3,SMARCC2,SON,MYCBP2,KIF1B,CBX5,NR2C2,UGT8,WNK1,ZXDA" MicroRNA hsa-miR-425-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-12 6.80E-09 2.02E-12 1.86E-11 32 144 "TAOK1,ZBTB10,INSYN2B,LDHD,BTK,CDC25B,FOXN3,CLU,QKI,ZC3H11A,EXOG,DPYSL2,FRY,FGFR3,SYNCRIP,HSP90AA1,IGSF1,STMN1,OCRL,PNMA8A,PPP4R3A,RUFY2,ZHX3,DICER1,BHLHB9,BEX4,RUSC1,RPL7L1,PLSCR4,KAT6A,CERS6,GAN" MicroRNA hsa-miR-6500-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-12 7.32E-09 2.17E-12 2.00E-11 40 217 "SERPINA3,AS3MT,BRAP,SLC12A5,HACE1,SFMBT2,PDXK,ZNF583,ISPD,FOXN3,SUSD5,USP6NL,DCC,SGSM2,GNE,CELSR3,MRNIP,PNMA2,KBTBD12,SEPT9,GPR75,ADAP1,KAT7,GUCY1A2,SCRG1,SLC11A2,CCSER2,BDNF-AS,ZNF844,CEP97,SLC25A36,MYO18A,KANSL3,CDK19,AKNA,PCDHA6,GALNT17,BHLHB9,EVI5,JMJD1C" MicroRNA hsa-miR-1911-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-12 7.54E-09 2.24E-12 2.06E-11 23 75 "DNAH17,ATP1A1,MICAL2,NCAN,DBT,PHC2,PRRC2B,GPR26,HMGB1,KCNH1,NUMA1,PALM,PDE4A,SEPT4,PTPA,QDPR,ALG9,TMEM156,TRIM67,ZFR2,ZNF106,TMEM237,GAN" MicroRNA "AGGGCCA,MIR-328:MSigDB" "AGGGCCA,MIR-328:MSigDB" MSigDB 1.34E-12 7.54E-09 2.24E-12 2.06E-11 23 75 "USP37,PRX,NRP2,HAP1,DYNC1I1,TESK2,AFF2,GPM6A,NR3C1,ATXN2L,VSIG4,LRRC75A,ZC3H12B,SNRK,LGR4,SCN2B,SLITRK3,ST3GAL3,WDTC1,SOX11,ZNF423,SEPT3,PLCB1" MicroRNA hsa-miR-4707-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-12 7.54E-09 2.24E-12 2.06E-11 27 104 "XKR4,ATP1B3,LDHD,ZMYM4,DIS3L,ENTPD4,PITPNM3,MYADM,DNAL1,MRPL37,SEC23B,KIAA1841,MFSD2A,DDX19B,HMGB1,METTL21A,MBD1,GDPD1,HSPA4L,SEPT8,KLHL7,WWC1,KIAA0930,SZT2,THRA,DAAM2,DPYSL5" MicroRNA hsa-miR-6847-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-12 7.74E-09 2.30E-12 2.11E-11 34 162 "INTS2,CARNS1,ATP1B3,MTMR3,DDR1,DIRAS1,PHF19,DCC,PLEKHM1,POM121,ST8SIA3,ANKRD46,MTSS1L,TUBB4A,AMOTL2,TMEM151A,HSP90AA1,IDH3A,NKD1,NAT8L,MPP2,TMOD2,PLEC,PPP2R5E,ELP2,GALNT10,MYO18A,SLC8A1,SLC8A3,NEK4,SLC37A2,TPM3,CIAPIN1,GAN" MicroRNA hsa-miR-5189-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-12 8.09E-09 2.40E-12 2.21E-11 44 257 "SLC24A4,HACE1,KIAA1614,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,WASF3,CRCP,GPR75,B4GALNT4,GRM1,DDX19B,DOCK7,MYBPC1,SLC11A2,OLR1,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,MAGI3,EMC1,AHCYL2,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-1185-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-12 8.10E-09 2.40E-12 2.21E-11 29 120 "ZNF608,PITPNM2,VAT1L,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,BRPF3,EML4,GRIK3,NCOA7,MBNL1,SESN3,KCNK10,PCSK1,PFKFB2,TMEM104,ROBO1,PKNOX2,KIF13A,DIP2A,GPRIN3,FBXL16,TMOD1,USP1,WNK1" MicroRNA hsa-miR-500a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-12 8.31E-09 2.46E-12 2.27E-11 32 145 "APP,DNAH17,CCNT1,RGS6,FSD1L,POLR1B,ST6GALNAC3,GABRG2,MTHFD2,PRRC2B,GPM6B,RNF165,HAS2,ZIC5,SLC35G1,MBNL1,MYO5A,PXK,PLEKHB2,GSTCD,PGBD4,SLC1A2,SLC8A1,TACC1,SIK3,NR2C2,AMOT,FRRS1L,KCNT2,LYPD6,VANGL2,ZDHHC20" MicroRNA hsa-miR-6773-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-12 8.31E-09 2.46E-12 2.27E-11 32 145 "ADCY2,TEX22,SFMBT2,DPY19L3,COL9A1,ZSCAN23,DBT,OPTN,TUBD1,FAXC,GPR26,TPPP,GRIK3,KAT7,KLF12,MAP4,GPSM2,STRN3,PIGG,MTMR10,ZYG11B,HSPA4L,BDP1,ERC1,SEPT3,KLHL7,KIAA0930,AP4E1,ZNF34,ZNF106,ZNF74,SLC38A1" MicroRNA "GGTGAAG,MIR-412:MSigDB" "GGTGAAG,MIR-412:MSigDB" MSigDB 1.55E-12 8.69E-09 2.57E-12 2.37E-11 20 56 "FMNL2,ANK2,PKP4,PRX,CDK5R1,BSN,BTRC,RAB28,ARMC8,ELMSAN1,TAOK3,DLC1,FOXO3,FAM222A,SATB1,SOX6,WDTC1,IQSEC2,NKAIN2,CSDE1" MicroRNA hsa-miR-4695-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-12 8.94E-09 2.65E-12 2.44E-11 33 154 "ARID1A,PWWP2A,SLC7A14,DOCK11,AKAP6,RTTN,HINFP,PYGO1,DRP2,GNE,KRBA2,HEYL,COQ7,IGSF6,MYOZ2,GPR75,SCRG1,IL6R,GPR155,MOG,SAMD5,FITM2,MTMR10,PGBD4,UEVLD,SCN7A,HSPA4L,CXXC4,MYO16,SSTR2,DIP2A,ARL10,USP1" MicroRNA hsa-miR-3614-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-12 8.95E-09 2.65E-12 2.44E-11 41 228 "SERPINA3,AS3MT,BRAP,SLC12A5,HACE1,SFMBT2,PDXK,ZNF583,ISPD,FOXN3,MICAL2,SUSD5,USP6NL,SGSM2,CALN1,GNE,CELSR3,MRNIP,PNMA2,KBTBD12,GAP43,SEPT9,GPR75,ADAP1,CECR2,KAT7,GUCY1A2,SCRG1,SLC11A2,CCSER2,PRKCB,BDNF-AS,ZNF844,CEP97,MYO18A,CDK19,AKNA,PCDHA6,BHLHB9,EVI5,JMJD1C" MicroRNA hsa-miR-6776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-12 9.00E-09 2.66E-12 2.45E-11 37 190 "TXNDC16,PDZD4,NIPA1,FOXK1,ZNF555,COL9A2,SOCS5,UBXN2A,MTX3,ZBED3,RNPS1,GRK4,MPP2,CCDC80,TNPO2,STK32A,PEX2,RAB5B,CEP97,PRRT2,KCNIP3,IL17RB,MAGI3,AMBRA1,MYH15,MBD5,MCF2L2,SSTR2,ZSCAN29,C3orf70,TPM3,SSBP2,USP1,DHX33,SLC30A4,TRIM16L,GAN" MicroRNA hsa-miR-4465:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-12 9.00E-09 2.66E-12 2.45E-11 37 190 "SDE2,MTA3,ZNF608,ATP2B1,ACBD5,PDE4DIP,KIAA0408,ZBTB24,SACS,RABGAP1L,RGS17,FKTN,FAXC,TNRC6A,KIF3A,ZBTB45,EID2B,MAT2A,BLOC1S2,ZNF426,PSAT1,NWD1,SLC25A36,ARMH4,LRRTM4,SFPQ,FAM126B,EPB41L3,DIP2A,ALG1,AGTPBP1,ASXL3,SSBP2,TUB,UBE2H,WNK1,VANGL2" MicroRNA hsa-miR-6860:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-12 9.28E-09 2.74E-12 2.53E-11 44 258 "SLC24A4,HACE1,KIAA1614,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,WASF3,CRCP,GPR75,GRM1,DDX19B,DOCK7,MAP4,MYBPC1,SLC11A2,OLR1,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,MAGI3,EMC1,AHCYL2,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-6722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-12 9.31E-09 2.75E-12 2.53E-11 36 181 "ELFN2,RNF157,SEMA7A,HCN2,CANX,HEYL,IRAK4,WAC,TUBB4A,DLC1,PDLIM5,CELF1,TMEM151A,GFER,C5orf24,KCNK3,MSI1,PKD1,PLEC,SLC25A23,PACSIN1,TNPO2,POLR2F,NCR3LG1,TMEM145,RAB5B,SARS,HES6,SP2,NFASC,CLASP1,ASXL3,ZFP91,GDPD5,ITM2C,HNRNPA3" MicroRNA hsa-miR-5697:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-12 9.42E-09 2.78E-12 2.56E-11 35 172 "SDE2,ZNF608,CDC14B,ATP2B1,CCNT1,ACBD5,NOS1AP,KIAA0408,SACS,PLEKHA1,RGS17,SLC43A2,FAXC,TXNL4A,TNRC6A,KIF3A,ZBTB45,LIFR,MAT2A,BLOC1S2,ZNF426,PTAFR,SLC25A36,PGBD4,ARMH4,SFPQ,FAM126B,TROVE2,EPB41L3,DIP2A,ALG1,WWC1,UBE2H,WNK1,VANGL2" MicroRNA hsa-miR-548j-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-12 1.00E-08 2.96E-12 2.73E-11 38 200 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,TNS1,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-12 1.00E-08 2.96E-12 2.73E-11 38 200 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154,IFT88" MicroRNA hsa-miR-3127-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-12 1.12E-08 3.30E-12 3.04E-11 34 164 "ASGR1,DCAF5,CBS,NUMBL,TENM4,CYBB,FGFR1OP2,IP6K1,KIAA0319,CALN1,KLHL5,PHF20L1,STARD3NL,CDHR1,REEP2,WAC,CELF1,GALC,KCNMB4,HSP90AA1,METTL21A,STMN1,LSAMP,MDFI,NASP,POU6F1,GTDC1,TMLHE,KIRREL1,SHANK2,MAPK8IP3,LAT2,PMEPA1,CERS6" MicroRNA "GTATGAT,MIR-154:MSigDB" "GTATGAT,MIR-154:MSigDB" MSigDB 2.03E-12 1.14E-08 3.36E-12 3.10E-11 21 63 "ARID1A,CSMD3,PPP4R4,ZMYM4,TMEM184B,CNR1,IFFO1,GDA,MAGI2,DYRK1A,ETV1,GAD2,GALC,GPM6A,KCNMA1,PDE4D,RBBP6,RFX3,RNF220,PUM2,SIRT1" MicroRNA "GTATGAT,MIR-487:MSigDB" "GTATGAT,MIR-487:MSigDB" MSigDB 2.03E-12 1.14E-08 3.36E-12 3.10E-11 21 63 "ARID1A,CSMD3,PPP4R4,ZMYM4,TMEM184B,CNR1,IFFO1,GDA,MAGI2,DYRK1A,ETV1,GAD2,GALC,GPM6A,KCNMA1,PDE4D,RBBP6,RFX3,RNF220,PUM2,SIRT1" MicroRNA hsa-miR-96-5p:Functional MTI Functional MTI miRTarbase 2.09E-12 1.18E-08 3.47E-12 3.19E-11 38 201 "SLC25A25,ADCY6,TAOK1,ALK,JAZF1,NIPA1,SCARB1,ARHGEF2,BAG4,PITPNM3,APPL1,PHF19,CDON,EIF4G1,TUBD1,PRMT5,FOXO3,GABRB1,ATP8A2,MALT1,TNRC6A,MITF,NPTX1,PFKFB3,PMS2,MED1,RAB5B,ATXN1,ANKRD36,SOX5,CAMTA1,SIN3B,ZEB1,TMPO,SGK3,RPL7L1,SLAIN1,EVI5" MicroRNA hsa-miR-552-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-12 1.21E-08 3.57E-12 3.28E-11 30 130 "INTS2,HACE1,MTMR9,CLOCK,VCAN,ELMSAN1,ANKRD46,SH3GLB1,EPS8,GABRB1,WASF3,EML4,KCNB1,CLVS2,LSAMP,MBNL1,XRRA1,NFYA,OGDH,CCSER2,PLCL1,TNPO2,CRLS1,CEP97,ZYG11B,SHC4,CUX2,SEZ6L,CADM1,SYNC" MicroRNA hsa-miR-423-3p:mirSVR_highEffct hsa-miR-423-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.25E-12 1.27E-08 3.73E-12 3.44E-11 29 122 "LINC00847,CAMK2A,CNOT8,NDST3,CREM,CMTM5,RHOBTB1,DTNA,FRY,KAT8,POLK,DKK3,MFSD2A,AP4S1,HNMT,KCNN3,MEIS1,NCAM1,SLC11A2,EPB41L4B,SLC6A15,FIGN,MIR124-2HG,SMARCE1,WDTC1,SYT1,MLST8,PRRT1,ATP6V0E2" MicroRNA hsa-miR-664a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-12 1.28E-08 3.76E-12 3.46E-11 25 91 "ARID1A,ADCYAP1R1,KIAA1211,CDK13,CALM1,NIPBL,EDN1,EN2,GPR26,PTPRT,HLF,ZNF678,SLC35G1,MAGEL2,MAPK8,TMLHE,MEG3,CHD9,ZNF667,ZNF415,VLDLR,WNT7A,ZNF23,SIGLEC10,NAV2" MicroRNA hsa-miR-1234-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.32E-12 1.30E-08 3.84E-12 3.54E-11 33 156 "ATP1B3,ZBED1,STOML1,ENTPD4,DNAL1,GNE,IRAK4,MRPL37,TLR7,APOPT1,FUT9,KIAA1841,GBX2,SRCAP,TDRKH,MFSD2A,HAS2,ATCAY,METTL21A,MBD1,PKD1,GDPD1,OCIAD1,NWD1,DCUN1D2,SETD5,ZNF430,SP2,ZBTB43,KIAA0930,ZMAT3,ZNF610,MEAF6" MicroRNA hsa-miR-4666a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-12 1.37E-08 4.05E-12 3.73E-11 24 84 "GPR158,TNRC6C,BACH1,JAZF1,ISPD,PLXNA4,LIN54,CERCAM,ENPP6,MMADHC,GRIK3,ZDHHC15,C2orf72,KLHL23,KCNK1,P2RY1,FAM98B,PROX1,GDPD1,UHRF1BP1,RPH3A,SEPHS1,UNC5B,TUBB2A" MicroRNA hsa-miR-548i:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-12 1.38E-08 4.06E-12 3.74E-11 38 202 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,TTC13,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-8060:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-12 1.40E-08 4.11E-12 3.79E-11 23 77 "USP37,CA8,CCNT1,LONRF2,BAG4,CPS1,EDIL3,EDN1,TENM1,PLEKHA1,EIF1,NEURL4,LIFR,FTO,MAPK8,PEX2,SH3TC2,ATXN1,NBPF1,LGI3,TAF6,RBFOX2,PITPNB" MicroRNA hsa-miR-4684-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-12 1.41E-08 4.15E-12 3.83E-11 47 292 "ADD1,PTCHD1,KIAA1324,TAOK1,MARCH4,ANK1,MARK4,NUMB,MYOM2,CRY2,CTH,USP6NL,KIAA0513,TMEM170A,FBXO25,MRO,RCSD1,DKK3,NCKAP1,GRK4,AGBL5,SAMD5,CCDC80,PAK3,FAT3,PKIA,PTPRB,RAB5B,C12orf49,RORB,NCBP3,TRA2B,MAGI3,PEX26,SMARCE1,TROVE2,EPB41L3,SYT11,FAM208A,ALG1,HHIP,SLC44A1,TPM3,TBC1D15,ZNF708,ZNF70,DHX33" MicroRNA hsa-miR-3679-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-12 1.50E-08 4.40E-12 4.05E-11 32 148 "ACTN2,AK2,TAOK1,LGR5,DCAF5,ZNF385A,HINFP,TBC1D5,KLHL5,FAM13A,WAC,IP6K2,SEMA4D,ST6GALNAC3,DKK3,GABRA1,SRRM4,GPR26,IL1RAPL1,MDFI,MITF,CD200,TMOD2,PKIA,PTPRE,NPAS3,INKA2,NSFL1C,ALG1,TNS1,DOK6,SLC38A1" MicroRNA hsa-miR-6768-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-12 1.50E-08 4.40E-12 4.05E-11 32 148 "SEMA4G,ARHGDIA,CCAR2,ZNF583,CD81,SLC24A2,CREB5,NOS1AP,RASSF2,PITPNC1,WAC,TESK2,SPECC1,FAM120B,GRID1,NR3C1,IL1RAPL1,NXPH2,SESN3,NAP1L1,NOS1,PLCL1,PKN2,CNNM2,ZMAT4,ZNF532,UNC5B,NACC2,TPM3,MTCH1,DHX33,MVB12B" MicroRNA hsa-miR-550:PITA hsa-miR-550:PITA_TOP PITA 2.80E-12 1.57E-08 4.62E-12 4.25E-11 27 107 "OSBPL8,CDK13,ADGRB1,AHCTF1,TM9SF4,CTIF,SV2A,DYRK1A,YAF2,EGR3,EMX2,MRVI1,CAB39,RAB30,ADAMTS6,IBA57,MAT2A,PDGFRA,STRN3,PPP2R5E,RIPOR1,GTDC1,SOX11,ARHGEF12,LYPD6,DPYSL5,DPF3" MicroRNA hsa-miR-7107-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-12 1.57E-08 4.62E-12 4.25E-11 33 157 "ATP1B3,ZBED1,STOML1,ENTPD4,DNAL1,GNE,IRAK4,MRPL37,TLR7,APOPT1,FUT9,KIAA1841,GBX2,SRCAP,TDRKH,MFSD2A,HAS2,ATCAY,METTL21A,MBD1,PKD1,GDPD1,OCIAD1,NWD1,DCUN1D2,SETD5,ZNF430,SP2,ZBTB43,KIAA0930,ZMAT3,ZNF610,MEAF6" MicroRNA "AAGTCCA,MIR-422B:MSigDB" "AAGTCCA,MIR-422B:MSigDB" MSigDB 2.88E-12 1.62E-08 4.75E-12 4.37E-11 21 64 "CALN1,DSCAM,EDN1,EN2,ZIC4,FOXG1,PTPRT,FRMD5,STXBP5,HECTD2,NTRK3,PPP3CA,SOX6,DHX30,UHRF1BP1L,IQSEC2,NEK4,SYN2,CUX2,NSD1,NSD2" MicroRNA "AAGTCCA,MIR-422A:MSigDB" "AAGTCCA,MIR-422A:MSigDB" MSigDB 2.88E-12 1.62E-08 4.75E-12 4.37E-11 21 64 "CALN1,DSCAM,EDN1,EN2,ZIC4,FOXG1,PTPRT,FRMD5,STXBP5,HECTD2,NTRK3,PPP3CA,SOX6,DHX30,UHRF1BP1L,IQSEC2,NEK4,SYN2,CUX2,NSD1,NSD2" MicroRNA hsa-miR-4477a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.99E-12 1.68E-08 4.93E-12 4.54E-11 31 140 "BRAP,BBOX1,SEMA7A,FOXN3,DLGAP3,BTF3L4,FEZ2,PHF19,FEM1B,ELAVL2,PLEKHA1,ACSL4,SCML2,MTHFD2,GRB10,MIER3,ZIC5,LIMS1,PDPK1,PSAT1,GDPD1,RPL15,UEVLD,CLIP1,SLC6A8,SMOC1,DOCK9,CBX5,UGT8,WNK1,GAL3ST3" MicroRNA hsa-miR-1297:Functional MTI Functional MTI miRTarbase 3.08E-12 1.73E-08 5.08E-12 4.68E-11 37 194 "SDE2,MTA3,ZNF608,ATP2B1,ACBD5,PDE4DIP,KIAA0408,ZBTB24,SACS,RABGAP1L,RGS17,FKTN,FAXC,TNRC6A,KIF3A,ZBTB45,EID2B,MAT2A,BLOC1S2,ZNF426,PSAT1,NWD1,SLC25A36,ARMH4,LRRTM4,SFPQ,FAM126B,EPB41L3,DIP2A,ALG1,AGTPBP1,ASXL3,SSBP2,TUB,UBE2H,WNK1,VANGL2" MicroRNA hsa-miR-3714:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.21E-12 1.80E-08 5.29E-12 4.88E-11 40 223 "SDE2,RNF157,HECW2,ZNF582,BTRC,FOXK1,CBFA2T2,MYOM2,CFL2,DLGAP3,QKI,HAPLN1,CTNND1,FAM131B,MRNIP,AMOTL2,MALT1,STARD3,ZNF496,C5orf24,RBPJ,COMMD5,NFIX,NLE1,SMOX,NCR3LG1,RAB5B,SBF1,IL17RB,CPEB3,TROVE2,ZSCAN29,NEK4,SATB2,ERCC6L2,RBFOX2,TOM1L2,DPYSL5,EVI5,URM1" MicroRNA hsa-miR-885-3p:mirSVR_highEffct hsa-miR-885-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.23E-12 1.81E-08 5.31E-12 4.89E-11 32 149 "ARID1A,KIAA1324,SUGT1P4-STRA6LP-CCDC180,INSYN2B,CACNB2,AHCTF1,RGS6,DYRK1A,EBI3,EGFR,GOLGA7,VPS26C,CAP2,MYLK2,ZNF827,GPR173,PPP3CB,BCAS3,WBP1L,SIDT1,CCDC40,SEC61A2,RAVER2,STK32B,SCMH1,MYO16,ZSWIM8,AGTPBP1,SEZ6L,TPM1,PRMT8,MEIS3" MicroRNA hsa-miR-554:PITA hsa-miR-554:PITA_TOP PITA 3.25E-12 1.83E-08 5.35E-12 4.93E-11 22 71 "LRFN1,BTRC,CACNB2,QKI,BTF3L4,MAGI2,SMG7,SV2A,G3BP2,ABI1,EFNA3,YAF2,EIF1,TAOK3,HSF2,MITF,PIK3R1,KCTD15,PALLD,TEX2,NXT2,TMEM237" MicroRNA "AGTCTTA,MIR-499:MSigDB" "AGTCTTA,MIR-499:MSigDB" MSigDB 3.25E-12 1.83E-08 5.35E-12 4.93E-11 22 71 "LRCH2,ZBTB10,PTBP2,CFL2,QKI,FAM131B,MYEF2,TESK2,EML4,ARHGAP12,NOVA1,ENPP2,ZNF655,PPP3CA,RNF220,RIC8B,SOX6,SOX5,SOX11,AZIN2,RALYL,NAV2" MicroRNA hsa-miR-601:PITA hsa-miR-601:PITA_TOP PITA 3.30E-12 1.85E-08 5.43E-12 5.00E-11 20 58 "TMEM132B,ADGRB1,BCL2L2,SYNGR3,ZNF385A,DYRK1A,PCDH11X,KDM2B,CIT,IL1RAPL1,MIER3,SNRK,SH3TC2,FIGN,MCMBP,R3HDM2,SOX11,SIRT1,FMN2,ZBTB38" MicroRNA hsa-miR-559:Functional MTI Functional MTI miRTarbase 3.36E-12 1.89E-08 5.53E-12 5.09E-11 38 204 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,ERBB2,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA "CAGGGTC,MIR-504:MSigDB" "CAGGGTC,MIR-504:MSigDB" MSigDB 3.36E-12 1.89E-08 5.53E-12 5.09E-11 23 78 "ZNF608,PCDH10,OGT,CHRD,CAMK2G,USP2,CNTFR,CEP170,NTM,SUGP2,EPB41,BAIAP2,ZMYND11,PCDH17,TMEM121B,GRM3,IL1RAPL1,BACH2,NFIX,CDIP1,MCMBP,SMPD3,VANGL2" MicroRNA hsa-miR-4695-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.38E-12 1.90E-08 5.55E-12 5.12E-11 54 370 "ABCF1,ADD2,SLC24A4,MTUS1,CDC14B,ARHGDIA,ATM,ZNF583,BTRC,DDR1,CANX,NDST3,NRXN3,SUMF2,LETMD1,MYADM,KIAA0513,LIN54,TMEM170A,ELMSAN1,TNK2,ANKMY1,MRVI1,ZNF585B,HHIPL1,SESN1,GPR75,GNG4,KIF3A,ATOH8,PPM1L,NBL1,ZC3H12B,NELL2,NUCB1,FTO,PLXNB1,POLR2F,MTMR10,BSDC1,RFX2,ALG9,SLC30A10,STUM,FAM102A,MAGI3,SLC2A5,ATF7IP,SLIT1,UNC5B,FAM168A,ACSBG1,SLC37A2,TPM3" MicroRNA hsa-miR-4793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-12 2.05E-08 5.99E-12 5.52E-11 31 141 "SLC25A25,TAOK1,SMIM17,BSN,MAP7,KIAA1549L,BAG4,IGSF6,PCDH17,GNAS,HMGB1,IL6R,MAPT,CHIC1,PIK3R1,KCTD15,ZMAT4,ALG9,STX1B,SEMA6D,PEAR1,BCAN,SLC1A7,BDP1,FNBP1,ELOVL4,DAAM2,MGAT5B,ZNF70,ZNF195,WIPF2" MicroRNA hsa-miR-1288:PITA hsa-miR-1288:PITA_TOP PITA 4.05E-12 2.27E-08 6.65E-12 6.13E-11 21 65 "USP37,CAMK2G,CANX,CLCN3,OLFM1,FGF13,TBR1,GRIK2,IL1RAPL1,NEUROD1,GPR137C,PROX1,ARID4A,ZNF821,FBXO11,NMNAT2,ANKRD28,ANO4,SZT2,WNK1,KAT6A" MicroRNA "ATCTTGC,MIR-31:MSigDB" "ATCTTGC,MIR-31:MSigDB" MSigDB 4.05E-12 2.27E-08 6.65E-12 6.13E-11 21 65 "CADPS,NUMB,ELMSAN1,G3BP2,TMEM35A,WAC,ADAM28,GRM7,BACH2,NNAT,IGSF11,STRN3,PTPRE,ARID4A,SNX22,MPRIP,PLCB1,TACC1,FNDC5,SLC17A6,FZD3" MicroRNA hsa-miR-1255b:PITA hsa-miR-1255b:PITA_TOP PITA 4.29E-12 2.41E-08 7.04E-12 6.48E-11 24 86 "TAOK1,SPOP,CNTNAP1,GPAM,NCOA1,CAMK2G,RUNX1T1,MYRIP,RIMS3,MFAP3L,FOXO3,BACH2,C5orf24,LRRTM3,MAP2,PPP3CA,NLGN1,SLC6A1,CAMTA1,RPGRIP1L,FNDC5,CELF4,REEP1,RNF146" MicroRNA hsa-miR-1255a:PITA hsa-miR-1255a:PITA_TOP PITA 4.29E-12 2.41E-08 7.04E-12 6.48E-11 24 86 "TAOK1,SPOP,CNTNAP1,GPAM,NCOA1,CAMK2G,RUNX1T1,MYRIP,RIMS3,MFAP3L,FOXO3,BACH2,C5orf24,LRRTM3,MAP2,PPP3CA,NLGN1,SLC6A1,CAMTA1,RPGRIP1L,FNDC5,CELF4,REEP1,RNF146" MicroRNA hsa-miR-3187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.33E-12 2.43E-08 7.11E-12 6.55E-11 43 255 "SLC24A4,HACE1,KIAA1614,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,WASF3,CRCP,GPR75,GRM1,DDX19B,DOCK7,MYBPC1,SLC11A2,OLR1,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,MAGI3,EMC1,AHCYL2,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-8055:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-12 2.53E-08 7.40E-12 6.81E-11 49 318 "AS3MT,ADCYAP1R1,MTA3,TAOK1,CEP126,ISPD,CBS,CD86,TBRG4,AKAP5,RTTN,RNF14,USP6NL,LONRF1,JAKMIP2,CELSR3,SRARP,PCYOX1,SRCAP,TNRC6A,GLUL,LINC01551,ZDHHC15,SCIN,IBA57,CLVS2,MBD1,MKLN1,MOG,TBC1D25,PDE3A,SMIM7,ZNF426,STRN3,CNTLN,MTMR10,MSANTD2,SETD5,ELP2,SCN2B,ELMOD1,PDZD2,TMEM136,KIAA0930,TNS1,ZNF708,ZXDA,LMAN2L,PHTF2" MicroRNA hsa-miR-611:PITA hsa-miR-611:PITA_TOP PITA 4.51E-12 2.53E-08 7.40E-12 6.81E-11 13 22 "XKR4,DDX3Y,PICK1,APH1A,EIF4G1,SEMA6C,NFIX,GTDC1,LHFPL4,VAMP1,SYN1,RIMBP2,TRPS1" MicroRNA hsa-miR-3942-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-12 2.54E-08 7.40E-12 6.82E-11 23 79 "NUMB,TBPL1,BAG4,ACBD5,CPEB2,RBM12,YAF2,EN2,SESN1,TNRC6A,C5orf24,IL6ST,RBBP6,FIGN,SETD5,TMEM100,KCNIP3,MPRIP,ACSBG1,RGMB,RPL7L1,VSNL1,GAN" MicroRNA hsa-miR-7156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-12 2.54E-08 7.40E-12 6.82E-11 23 79 "SPOP,FOXK1,C1orf52,BTF3L4,USP6NL,YTHDC1,ST8SIA3,YAF2,SH3GLB1,SEZ6,ERBB2,CACNG2,STAMBP,TUBGCP4,TNRC6A,ATOH8,NCKAP1L,IGF1,PDE1B,ZNF793,SOX1,DNAJC9,TRPS1" MicroRNA hsa-miR-30d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.84E-12 2.72E-08 7.94E-12 7.31E-11 33 160 "CDK13,CACNA1E,ENTPD4,MAML1,YTHDC1,FAM107B,DYRK1A,EIF1,CAMSAP1,NPTN,GABRA2,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,MDM4,KCTD6,NUCB1,PCSK2,CAMKV,EPB41L4B,SH3TC2,CCDC25,SCP2,GALNT10,SLC1A2,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2" MicroRNA hsa-miR-4530:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-12 2.77E-08 8.08E-12 7.45E-11 30 134 "MIER1,SFMBT2,GPR146,LDLRAD4,NCOR2,CSNK1E,NCAN,FAM131B,DMPK,FGFR1,GRID1,FAM107A,RNFT2,MID1,PTCH1,PRRT2,ALG9,ATAT1,SALL1,SCN4B,ZFP30,MPRIP,ZNF34,ZFP91,WBP2,LRTM2,RPL7L1,BCL2L13,CCDC14,ZNF154" MicroRNA hsa-miR-4290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.01E-12 2.82E-08 8.21E-12 7.56E-11 25 94 "TMEM132B,CS,TENM4,RGS6,CTIF,WDPCP,APC2,ANKMY1,F3,CSDC2,CRCP,PRRC2B,GPR26,GPR45,HPR,KCNH1,MMP17,KCTD15,CYB561D1,MAPKBP1,ZCCHC24,NFASC,BCL2L13,MTCH1,KCNK12" MicroRNA hsa-miR-1250-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.33E-12 3.00E-08 8.73E-12 8.04E-11 38 207 "NLGN4X,DDO,TMEFF1,CALM1,CBR1,CCNT1,C1orf52,TOGARAM2,APPL1,FEM1B,EPHB1,TBC1D16,TAOK3,SLC37A3,PDLIM5,ZNF274,COPS8,GPR26,KCNB1,MSANTD3-TMEFF1,SMIM7,MDGA2,SPDL1,ACSS3,RNASEL,GSTCD,CCDC25,ACER3,SALL1,NBPF1,PALLD,TROVE2,ALG1,ARHGEF12,LRRC8A,TNR,ATP6V0E2,PRDM10" MicroRNA hsa-miR-8068:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.48E-12 3.08E-08 8.97E-12 8.26E-11 26 102 "ARHGDIA,BAG4,NCAN,KIAA0408,JAKMIP2,DMD,EIF1,ENPP6,FGF14,JKAMP,GABRB1,SALL3,SESN3,HS6ST3,NEUROD2,OPCML,PDPK1,NCR3LG1,MARCH1,SH3TC2,SEMA6D,SEPHS1,PARD3,TNS1,VSNL1,ZNF74" MicroRNA hsa-miR-3663-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.59E-12 3.14E-08 9.15E-12 8.43E-11 39 217 "TMEM132B,NFS1,STOML1,TMEM184B,CSNK1G3,SEC14L5,MYADM,FGFR1OP2,KIAA0586,RABGAP1L,RPS6KL1,RCSD1,ZNF461,CRCP,GRID1,DDX19B,ATCAY,KCNN3,CYP27C1,MAN2A2,MYO5A,MYO6,NUCB1,SEPT4,POLR2F,PTAFR,DCUN1D2,KLHDC8A,SGSM1,NUBPL,ANKRD36,FAM126B,KIF1B,SSTR2,ZNF34,THRA,SGK3,ZNF70,DHX33" MicroRNA hsa-miR-328-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.60E-12 3.15E-08 9.17E-12 8.45E-11 28 118 "SLC12A5,CASKIN1,TXNDC16,TRMT9B,PHF12,PRX,ARHGDIA,BCL7A,NEURL1,CACNA2D2,ZNF385A,PYGO1,ERBB2,WAC,MTHFD2,GFER,CRCP,NFIX,PLEC,SDK2,HSD11B1L,SMTN,NMNAT2,USP22,RBFOX2,UBTF,MGAT5B,VGF" MicroRNA hsa-miR-6793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.68E-12 3.19E-08 9.29E-12 8.56E-11 32 152 "PLEKHG5,LRFN1,LGR5,CACNA1A,LURAP1,ELMO1,RTN3,RASL10A,NEURL4,DKK3,SRRM4,GLI2,ZNF638,RAB40B,GPD1,GSTM5,ARHGAP19,SLC6A17,MDGA1,KSR2,OPRL1,KCNK10,SKOR1,ZNF793,RBBP6,GTDC1,WLS,RAP1GAP2,SMOC1,ADAMTS17,DOK6,FAM181B" MicroRNA hsa-miR-3152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.03E-12 3.39E-08 9.86E-12 9.08E-11 23 80 "MTA3,CYBB,KIAA0319,DYRK1A,ABI2,GOLGA7,FLYWCH1,NXPH3,DDX19B,SOWAHA,KCNK1,NUCB1,POU3F2,RAB5B,STX1B,PEX26,LRRC55,FAIM2,TROVE2,AJAP1,FGD4,FAM124A,VLDLR" MicroRNA hsa-miR-188-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.04E-12 3.39E-08 9.87E-12 9.09E-11 30 135 "RNF150,MTA3,OSBPL1A,PHF12,AMER3,BACH1,IP6K1,MRPL37,GABRB1,RAPGEF6,GNAS,KIF3A,HAS2,MN1,PNMA3,SDK2,CNNM2,PTAFR,PEX2,ATG16L1,SPIN3,STUM,KIF21A,KANSL3,ZCCHC24,SMOC1,WBP2,ZNF711,GDPD5,GAN" MicroRNA hsa-miR-875-5p:TargetScan hsa-miR-875-5p TargetScan 6.07E-12 3.41E-08 9.92E-12 9.14E-11 22 73 "METAP1D,CASKIN1,LDLRAD4,RUNX1T1,CLOCK,EGFR,ELAVL4,EYA1,CECR2,GRID1,NEGR1,AQP11,NFIA,PDE4D,FTO,PACSIN1,IQSEC3,PPM1E,PEG10,FAM208A,SATB2,HNRNPA3" MicroRNA "ACACTCC,MIR-122A:MSigDB" "ACACTCC,MIR-122A:MSigDB" MSigDB 6.07E-12 3.41E-08 9.92E-12 9.14E-11 22 73 "SORCS1,ADGRB2,CDC42BPB,CS,G3BP2,DLG4,CD320,GALC,TNRC6A,BACH2,NEGR1,MARK1,MEIS2,GIT1,NTRK2,ZNF827,PAK3,MASP1,SLC4A3,FAM219A,DICER1,MICU3" MicroRNA hsa-miR-612:Non-Functional MTI Non-Functional MTI miRTarbase 6.46E-12 3.63E-08 1.06E-11 9.72E-11 43 258 "SLC24A4,HACE1,KIAA1614,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,WASF3,CRCP,GPR75,GRM1,DDX19B,DOCK7,MYBPC1,SLC11A2,OLR1,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,MAGI3,EMC1,AHCYL2,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA hsa-miR-513b-5p:Functional MTI Functional MTI miRTarbase 6.54E-12 3.67E-08 1.07E-11 9.83E-11 31 144 "TXNDC16,ANK1,ZNF583,ZNF555,DLGAP3,TOGARAM2,GREB1,NOS1AP,TM9SF4,DCC,GRM5,SYTL4,ZNF713,MAGEL2,NCR3LG1,OCIAD1,CSRNP3,SH3BP2,POGZ,DIP2A,ACSBG1,ANKRD28,SYT4,IQCE,NSD1,RPL7L1,TFIP11,SLC38A1,HNRNPA3,PHTF2,FXR1" MicroRNA hsa-miR-4689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.59E-12 3.70E-08 1.08E-11 9.90E-11 29 127 "APBB2,CACNA1B,GAPVD1,CTIF,SEC16A,BSCL2,EIF1,EN2,MRVI1,SYNCRIP,PDLIM5,METTL21A,PDE3A,ZNF426,TNPO2,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,WDTC1,NMNAT2,PEG10,ZC3H4,ZMAT3,TNS1,RASD2,SF1,WIPF2" MicroRNA hsa-miR-302a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.59E-12 3.70E-08 1.08E-11 9.90E-11 29 127 "KLRC4,CDC14B,LONRF2,CDR1,NRXN1,QKI,CPS1,FEZ2,USP6NL,SACS,G3BP2,FEM1B,SUCO,CBX1,IGF1,SLC35G1,CREG2,NEK1,DDR2,PIK3R1,PSAT1,ZMAT4,ELP2,AP1AR,FAM126B,HHIP,ZNF70,WNK1,SLC30A4" MicroRNA hsa-miR-548c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548aq-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ae-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548w:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ar-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ab:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548bb-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548au-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ad-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548as-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548h-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548y:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ap-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548o-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ay-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548ak:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-548am-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.80E-12 3.82E-08 1.10E-11 1.02E-10 37 199 "SDE2,PTCHD1,FAM135A,BACH1,FOXK1,PTBP2,NECTIN3,FRY,CELSR3,KATNAL1,POLR1B,SYNCRIP,MSANTD4,MTHFD2,GRM5,KIF3A,HSP90AA1,IL6ST,KLRC3,TM6SF1,MKLN1,CCDC80,PKD1,KLHL11,ALG9,CLIP1,TRA2B,LRRC55,PEG10,ZBTB43,NACC2,RPL7L1,UBE2H,VLDLR,ZNF711,ZBTB38,ZNF154" MicroRNA hsa-miR-7-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-12 3.84E-08 1.11E-11 1.02E-10 34 171 "NLGN4X,MTMR9,DGKI,KIAA1549L,DGKB,MYEF2,CPEB2,MAMLD1,TUBGCP4,COPS8,PCLO,HSP90AA1,C5orf24,KCNB1,LIFR,LYPLAL1,MDM4,OCRL,PAK3,PCMT1,EPB41L4B,TNPO2,PPM1B,CRLS1,ZNF354C,TAB2,KIAA1107,ARL10,SF1,WNK1,EVI5,ADAMTS9,HNRNPA3,SPATA13" MicroRNA hsa-miR-4650-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.13E-12 4.00E-08 1.16E-11 1.06E-10 27 111 "PLEKHG5,MTUS1,DYNLL1,SLC2A11,CRY2,DNAL1,E2F6,SH3GLB1,EIF4G2,TUBD1,EPS8,POLL,TDRKH,RABL2A,DDX19B,IL6ST,NAT8L,MDM4,MTRF1L,GDPD1,ZYG11B,FIGN,CSRNP3,AHCYL2,TPD52,SMARCAD1,FXR1" MicroRNA hsa-miR-409-3p:Functional MTI Functional MTI miRTarbase 7.13E-12 4.00E-08 1.16E-11 1.06E-10 27 111 "XKR4,C1QTNF3,DCAF5,MTMR7,FOXN3,CTNND1,GUCD1,CAMSAP1,STAG2,GAB1,GCK,MALT1,TNRC6A,GNAL,DIDO1,SESN3,CCDC80,MINDY2,RDX,RNASEL,ZFHX4,CPEB4,KDM4C,ZEB1,ZMAT3,TMPO,CSDE1" MicroRNA hsa-miR-6844:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.13E-12 4.00E-08 1.16E-11 1.06E-10 27 111 "RNF150,TNRC6C,ARNTL,CA8,CACNA1B,IP6K1,DYRK1A,YAF2,ZNF585B,FLT1,HBS1L,MTHFD2,PDE3A,PDPK1,PLCL1,PLP1,PRRX1,PKIA,ROBO2,TRAPPC13,ALG1,ZFP91,UBE2H,MEAF6,ZNF781,RNF146,GAN" MicroRNA hsa-miR-599:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.13E-12 4.00E-08 1.16E-11 1.06E-10 27 111 "SPOP,GAS7,ARSE,CBR1,UBXN2A,CTNND1,TOMM20,RASGRP1,CACNG7,ABI2,EIF4G2,IL1RAPL1,ELOVL5,PAX6,PLCL1,ENOX1,ZFHX4,SLC8A1,ATF7IP,SATB2,DOK6,NR2C2,VSNL1,STOX2,WIPF2,NETO2,GAN" MicroRNA hsa-miR-720:mirSVR_highEffct hsa-miR-720:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.13E-12 4.00E-08 1.16E-11 1.06E-10 27 111 "ADCY6,HECTD1,ABI3BP,CS,FEZ1,GOLGA7,FOXG1,KHDRBS3,GALR1,PRLHR,ADAMTS13,GRM1,RBPJ,DNHD1,BCAS3,RASGRF1,RNASE1,KLHDC8A,ROM1,SNX22,ST3GAL3,TSPYL2,SST,WDR7,ARL10,PRMT8,NHSL1" MicroRNA hsa-miR-141-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.37E-12 4.14E-08 1.19E-11 1.10E-10 30 136 "MTA3,SORCS2,WDR35,SMIM17,BID,SPAG9,ZFYVE9,TOGARAM2,TM9SF4,SIRPA,TMEM132C,GABRA1,WASF3,GBX2,ZNF638,ARHGAP19,ATXN2L,HMGB1,HSP90AA1,MYO5A,EPB41L4B,MSANTD2,AP1AR,ATXN2,KANSL3,SLIT1,DOK6,WNK1,FRMD6,GAN" MicroRNA hsa-miR-1285-3p:Functional MTI Functional MTI miRTarbase 7.37E-12 4.14E-08 1.19E-11 1.10E-10 43 259 "SLC24A4,HACE1,KIAA1614,ARSE,DPY19L3,ZNF445,SUSD5,UBXN2A,GAPVD1,RIPOR2,CENPL,MTX3,ZNF549,UFM1,CELF1,WASF3,CRCP,GPR75,GRM1,DDX19B,DOCK7,MYBPC1,SLC11A2,OLR1,PIK3R1,PKM,STRN3,PPP1R1A,TATDN3,BCAS3,PEX2,ZNF844,KLHL11,KLHDC8A,ZNF331,STUM,MAGI3,EMC1,AHCYL2,RPL7L1,TBC1D15,ZNF154,TRIM16L" MicroRNA "GTGTGAG,MIR-342:MSigDB" "GTGTGAG,MIR-342:MSigDB" MSigDB 7.84E-12 4.40E-08 1.27E-11 1.17E-10 21 67 "DDX3Y,CTNND1,PLPPR4,ZIC4,NBEA,CAMKK2,CCDC184,GRIN1,ATXN2L,MEIS1,MSI1,PDGFRA,KLK6,PTPRN,SOX6,SLC6A8,BTBD7,TAB2,SEPT3,NSD2,RICTOR" MicroRNA hsa-miR-141-3p:Functional MTI Functional MTI miRTarbase 7.91E-12 4.45E-08 1.28E-11 1.18E-10 31 145 "OGT,SEPT7,KIAA1549L,QKI,MAP4K4,CLOCK,RASSF2,ZEB2,ELAVL2,ELAVL4,CELF1,MALT1,KLF12,IPO5,MDM4,PPARA,MAPK9,PTPRD,SFPQ,WDR37,ELMO2,TET1,ZNF621,TROVE2,ERBIN,SEPT8,ZEB1,ZFPM2,ZMAT3,TIAM1,CLDND1" MicroRNA hsa-miR-4703-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.02E-12 4.50E-08 1.30E-11 1.20E-10 23 81 "NUMB,TBPL1,BAG4,ACBD5,CPEB2,RBM12,YAF2,EN2,SESN1,TNRC6A,C5orf24,IL6ST,RBBP6,FIGN,SETD5,TMEM100,KCNIP3,MPRIP,ACSBG1,RGMB,RPL7L1,VSNL1,GAN" MicroRNA hsa-miR-6087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.06E-12 4.53E-08 1.30E-11 1.20E-10 44 270 "PLEKHG5,ELFN2,TXNDC16,TRMT9B,PDXK,ASPA,FOXK1,CDR1,JAM2,PLAA,NCOR2,MICAL2,MYADM,KIAA0513,PHYHIP,SLC29A4,ABCC5,ECSIT,FECH,KBTBD12,NCKAP1,GCK,GNG4,KAT7,IGF1,MDM4,ZNF713,PIK3CD,A2ML1,PACSIN1,RBBP8,C12orf49,PTGR2,FNIP1,SEPHS1,FNBP1,PEG10,MCF2L2,CLASP1,TPM3,SSBP2,USP1,ZNF708,EVI5" MicroRNA hsa-miR-3065-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.11E-12 4.55E-08 1.31E-11 1.21E-10 29 128 "MTMR9,SPATA2,MYEF2,RAB39B,FCF1,ZNF585B,PNMA2,GABRA4,WASF3,TUBGCP4,IGF1,ZNF678,ITPKB,ARHGAP12,MDM4,CTNNA3,NCAM2,POLG,SNRK,PEX2,PRRT2,SEC31A,TET1,SOX1,SYPL1,SYT4,TMEM136,RPL7L1,SPATA13" MicroRNA hsa-miR-1247-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-12 4.60E-08 1.32E-11 1.22E-10 51 345 "PLEKHG5,RNF157,SLC24A4,LRFN1,ANK1,CDC14B,SLC7A14,KIAA1614,SFMBT2,PLAA,KIAA0408,KIAA0513,TMEM170A,DNAL1,SLC43A2,STX2,ECSIT,ZNF585B,FKTN,PDLIM5,BRSK1,NCKAP1,CRCP,GPR75,RFFL,HMGB1,LIMS1,MDM4,NEUROD2,PBX1,CCSER2,MTMR10,ZNF793,NWD1,RBBP8,ALG9,SNX22,RPS6KA2,PTGR2,ZFP30,SLC2A5,MCF2L2,LHPP,INKA2,TPCN2,ZNF106,SSBP2,USP1,ZNF70,EVI5,PARP11" MicroRNA hsa-miR-4710:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.21E-12 4.61E-08 1.33E-11 1.22E-10 32 154 "PNMA8B,TXNDC16,AK2,ARRB2,CFL2,PPP1R16B,NOS1AP,SEC16A,DNAH9,EDN1,EN2,ANKFY1,PDLIM5,SEPT9,POLL,SHISAL1,NOS1,TNPO2,MORC4,KCNIP3,SCN4B,EPN2,SP2,EMC1,AJAP1,ACSBG1,TPM2,SF1,ZNF70,WIPF2,ACTR3B,GAN" MicroRNA hsa-miR-22-3p:Functional MTI Functional MTI miRTarbase 8.27E-12 4.64E-08 1.34E-11 1.23E-10 33 163 "ACLY,NCOA1,BMP7,BMPR1B,FUBP1,FOXK1,RBM39,CSF1R,HDAC4,ERBB2,NR3C1,HMGB1,C5orf24,IBA57,MYO6,DNHD1,NTRK2,PIK3C2A,PPARA,PEX5,RAB5B,CHD9,TACC1,TMEM178B,WWC1,TCF7,SIRT1,TIAM1,TPD52L2,ELP5,VSNL1,HNRNPA3,NUP214" MicroRNA hsa-miR-3622b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.66E-12 4.86E-08 1.40E-11 1.29E-10 28 120 "SLC2A11,BACH1,CCNT1,MYOM2,CCPG1,DNAJB5,SEC14L5,NOS1AP,DNAH9,ABCC5,MRNIP,COQ7,SCML2,SEC24B,FOXO3,MSANTD4,CPLX2,RBPJ,MMP17,SFR1,PIK3CD,PRKACB,MAPK9,ZFP30,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-4487:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.67E-12 4.87E-08 1.40E-11 1.29E-10 39 220 "ZNF578,TRMT9B,AMH,GAS7,USP37,FOXK1,CCPG1,UBXN2A,DNAL1,HP1BP3,E2F6,ST8SIA3,STX2,FGFR1,RNPS1,HSF2,PLEC,FAT3,ALG9,CCDC25,MAP6D1,FNIP1,PEX26,MYH15,SMARCE1,IGSF9B,LHFPL4,ERC1,NFASC,LHPP,APOM,ACSBG1,FGD4,CYB561A3,THRA,TMEM9,PPIL6,USP1,PIANP" MicroRNA hsa-miR-188-5p:Non-Functional MTI Non-Functional MTI miRTarbase 8.94E-12 5.02E-08 1.44E-11 1.33E-10 27 112 "ADORA3,SPOP,AQP6,CACNA1A,VXN,SLC16A4,SEC31B,ELMSAN1,G3BP2,ABCC5,TMTC1,PLEKHA1,WASF3,KIF3A,ITGA7,KLHL23,MBNL1,C10orf105,PCDH9,CEP97,GTDC1,UBR7,ATXN1,GALNT10,MEAF6,PRDM2,KAT6A" MicroRNA hsa-miR-6895-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.18E-12 5.16E-08 1.48E-11 1.37E-10 35 182 "SPAG9,FMNL3,CBARP,USP6NL,TMEM170A,C2CD2L,RCAN1,UFM1,NCKAP1,DISC1,GRID1,SYTL4,LSAMP,DDR2,PALM,PDE3A,BSDC1,RDX,NCBP3,SCN2B,TRA2B,ZFP30,FAM214B,UNC5B,MCF2L2,LRRC4,DIP2A,TAL1,FAM208A,SZT2,HHIP,TPM3,ZNF708,NAV2,PLSCR4" MicroRNA hsa-miR-5585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.61E-12 5.40E-08 1.55E-11 1.43E-10 24 89 "TAOK1,SLC7A14,SLC4A4,ALDH7A1,FAM169A,PHF14,LONRF1,KMT5B,FER,DOT1L,PPARGC1A,LUZP2,NUDT21,RBPJ,DOCK7,SMAD9,HMGCLL1,KANSL1,FIGN,ATP8B4,SCN2B,RCOR3,SULF2,VSNL1" MicroRNA hsa-miR-339-5p:PITA hsa-miR-339-5p:PITA_TOP PITA 1.06E-11 5.96E-08 1.71E-11 1.58E-10 23 82 "CCAR2,HAP1,NRXN1,MAGI2,EMX2,AGAP3,BRSK1,SRRM4,HNRNPK,INSYN2,NNAT,NOVA1,CDK14,NXPH1,TMEM260,USP47,IGSF9B,THRA,ZFP91,TRPC3,UBE3A,TMEM237,SLC4A10" MicroRNA hsa-miR-4666b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-11 6.07E-08 1.74E-11 1.60E-10 21 68 "NLGN4X,TNRC6C,SLC7A14,FOXN3,NIPBL,VCAN,PLXNA4,C8orf37,EIF1,TBC1D16,PCSK2,PDE3A,PLP1,UEVLD,MGRN1,C5orf64,TNR,SSBP2,ZNF711,ZNF24,ZNF154" MicroRNA hsa-miR-3591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-11 6.07E-08 1.74E-11 1.60E-10 21 68 "KIF6,GPAM,ARNTL,CALM1,CDC42,ELMO1,SH3GLB1,CELF1,ZNF546,SMAD1,NCAM2,GPR137C,UHRF1BP1,ZNF793,SALL1,SGK1,SON,SOX11,CLASP1,SF1,CERS6" MicroRNA "GTACAGG,MIR-486:MSigDB" "GTACAGG,MIR-486:MSigDB" MSigDB 1.10E-11 6.19E-08 1.78E-11 1.64E-10 19 55 "SLC12A5,SORCS1,ARHGAP5,DYNLL1,ARMC8,DCC,SRGAP3,G3BP2,ELAVL2,FGF13,GABRB3,MARK1,PIK3R1,PPP3CB,RBBP6,PDZRN3,SMOC1,ST5,PUM2" MicroRNA hsa-miR-3177-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-11 6.23E-08 1.79E-11 1.65E-10 22 75 "ARID1A,TAOK1,DCAF8,TMEM130,DNAJB6,ABI2,AFF2,TACC2,GABRB3,GRIK3,KAT7,HMGB1,ZDHHC15,DOCK7,IL6ST,SLITRK3,RPH3A,KIF13A,SP4,ARHGEF9,SATB2,TUB" MicroRNA hsa-miR-374a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-11 6.23E-08 1.79E-11 1.65E-10 22 75 "AXIN2,GPR158,ZBTB10,MTMR9,FOXN3,ABI2,ELAVL3,C8orf37,SMC2,HSP90AA1,KCNJ3,PLCL1,SEMA6D,CSRNP3,SGK1,SMTN,SOX5,ZMAT3,ZNF106,ZNF154,TFIP11,PARP11" MicroRNA hsa-miR-4438:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-11 6.34E-08 1.82E-11 1.68E-10 49 326 "CLK4,ESYT2,MARCH3,ATM,ATP1B3,SLC2A11,ZMYM4,DIS3L,LETMD1,RNF14,SLC12A6,ABI2,EIF4G2,TUBD1,SLC43A2,CEP78,FDFT1,SPECC1,GABRB1,TRAF3IP2,TXNL4A,ZNF491,NKD1,IL6R,METTL21A,CYP27C1,LAMP2,CHST6,NODAL,ZNF426,MINDY2,OCIAD1,SETD5,HSPA4L,FAM126B,SP2,CLUAP1,ZNF621,PBLD,SYPL1,CBX5,PARD3,TPM4,RPL7L1,CFAP298,ZNF70,PMEPA1,SIGLEC10,AP3B2" MicroRNA hsa-miR-4673:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-11 6.48E-08 1.86E-11 1.71E-10 31 147 "LTBP4,APAF1,DNAH17,DDR1,NUMBL,NCAN,ANKMY1,TOMM40L,POLR1B,C15orf41,FUT10,GPR26,GRK4,RNF165,IRAK3,HMGB1,KCNH1,KCNJ11,CREG2,CDK18,QDPR,ELP2,PEAR1,SH3BP2,R3HDM2,PEX26,TRIM67,ARC,SLC37A2,RFTN2,AMZ1" MicroRNA hsa-miR-7-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.27E-11 7.13E-08 2.04E-11 1.88E-10 35 184 "NLGN4X,MTMR9,DGKI,KIAA1549L,DGKB,MYEF2,CPEB2,MAMLD1,EGFR,TUBGCP4,COPS8,PCLO,HSP90AA1,C5orf24,KCNB1,LIFR,LYPLAL1,MDM4,OCRL,PAK3,PCMT1,EPB41L4B,TNPO2,PPM1B,CRLS1,ZNF354C,TAB2,KIAA1107,ARL10,SF1,WNK1,EVI5,ADAMTS9,HNRNPA3,SPATA13" MicroRNA hsa-miR-6891-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-11 7.44E-08 2.13E-11 1.96E-10 30 139 "ARID1A,XKR4,SORCS2,ZNF578,TRMT9B,CDC14B,CANX,LIN54,CHRDL1,CACNG7,EN2,GJB1,MPP2,NBL1,NDUFA5,NOVA2,TMEM231,BSDC1,RUFY2,FAM168A,ASTN2,HHIP,NACC2,ASXL3,TPD52L2,TPM3,BCL2L13,WRN,ITM2C,SSPN" MicroRNA hsa-miR-4269:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-11 7.44E-08 2.13E-11 1.96E-10 30 139 "APAF1,BTK,FOXK1,NUMBL,DNAH9,TUBD1,IGSF6,TMEM132C,FDFT1,POLR1B,GABRB1,TXNL4A,B4GALNT4,ZIC5,KCNH1,CCDC80,NOS1,RMI1,SBF1,SH3BP2,R3HDM2,RUFY2,UNC5B,INKA2,GALNT17,TRPS1,TSN,RPL7L1,SIGLEC10,MVB12B" MicroRNA hsa-miR-505-3p:Functional MTI Functional MTI miRTarbase 1.33E-11 7.49E-08 2.14E-11 1.98E-10 39 223 "TMEM132B,LTBP4,TNRC6C,BTRC,CANX,PRC1,ZNF445,CSF1,SOCS5,RIMS4,PDE4DIP,FIS1,ANKRD13B,TUBB3,STAMBP,PNMA2,KCNMB4,PRRC2B,FUT10,NEGR1,IGF1,KCNH1,LIMS1,MYBPC1,NPTX1,POLG,SALL1,TET1,SOX11,SYT4,TAF9,TCF7L2,FBXL16,C5orf64,TP53BP1,TPD52,TUBB2A,PRDM10,HNRNPA3" MicroRNA hsa-miR-1289:PITA hsa-miR-1289:PITA_TOP PITA 1.37E-11 7.67E-08 2.20E-11 2.02E-10 25 98 "ANK1,CALM1,ZNF385A,PHC2,APH1A,TMEM35A,TTBK1,PLPP7,KCNA1,PDYN,XRN1,KCTD15,STRN3,ATXN7,SCN2A,FAM19A1,SCP2,FUZ,SOX11,CLASP2,DOCK9,AHCYL2,CADM1,ZIC2,GDPD5" MicroRNA hsa-miR-1224-3p:PITA hsa-miR-1224-3p:PITA_TOP PITA 1.41E-11 7.93E-08 2.27E-11 2.09E-10 26 106 "ADCY6,CDC42BPA,CABP7,PTBP2,NRXN3,HECTD1,CRY2,PPP1R16B,ALKBH8,ABCC5,SUCO,TTBK1,GRIN2D,KLF12,MPP2,PDPK1,TNPO2,FNIP1,PPP1R9A,BTBD3,VAMP1,ATP11A,CAMTA1,STMN4,WIPF2,SLC17A6" MicroRNA hsa-let-7g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-11 7.93E-08 2.27E-11 2.09E-10 26 106 "ARID1A,USP28,APP,MAP7,MAGED1,ABI2,WAC,DLC1,FYN,GABRB3,KAT7,BACH2,HMGB1,DOCK7,KCNB1,NFIX,OLR1,ZFYVE21,TRA2B,FNDC3A,PRRC2C,TMEM136,SLC44A1,ARL10,CADM1,URM1" MicroRNA hsa-miR-29c-3p:Functional MTI Functional MTI miRTarbase 1.47E-11 8.24E-08 2.36E-11 2.17E-10 42 254 "TXNDC16,ZBTB10,NUMB,FMNL3,CDC42,CREB5,CTNND1,ELMSAN1,FEM1B,SH3GLB1,GOLGA7,DOT1L,MTHFD2,RAB30,BACH2,HMGCR,IGFBP1,LIMS1,MYCN,NASP,ENPP2,KCTD15,PURG,PRKAB2,GTDC1,GLDN,SLC30A10,SGK1,SEC31A,MAPKBP1,FAM126B,HECW1,CEP68,C12orf76,MMS19,DICER1,SIRT1,TIAM1,ZFP91,TUBB2A,ZNF45,TMEM237" MicroRNA hsa-miR-1324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-11 8.37E-08 2.39E-11 2.20E-10 29 131 "SDE2,ADAR,NLGN4X,SLC24A4,FOXK1,CALM1,PRC1,TMEM184B,COL9A1,IP6K1,SPATA2,TACC2,ZNF274,MTHFD2,CSDC2,RNPS1,FERMT2,MUM1,BACH2,HSF2,AFF1,KSR2,P2RX7,PDE4D,PLXNB1,SLC1A2,NBPF1,SLIT1,URM1" MicroRNA hsa-miR-4677-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-11 9.06E-08 2.59E-11 2.39E-10 24 91 "SPOP,TNRC6C,C1orf52,USP6NL,YTHDC1,RCAN1,GOLT1B,ST8SIA3,YAF2,SEZ6,ERBB2,STAMBP,TNRC6A,ATOH8,NCKAP1L,XRRA1,NCAM2,PDE3A,PDE1B,SH3TC2,RAB3GAP1,SOX1,DNAJC9,TRPS1" MicroRNA hsa-miR-576-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-11 9.06E-08 2.59E-11 2.39E-10 24 91 "PHF12,SRSF11,LETMD1,HINFP,BLOC1S6,RABGAP1L,DLC1,SCARA3,FUT9,MTHFD2,AGFG1,KPNA5,SESN3,SDK2,PPP2R5E,ATXN1,SGK1,FAM102A,NAXD,ZFP91,TRPC3,ZNF708,ZNF24,STOX2" MicroRNA hsa-miR-3622a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-11 9.17E-08 2.62E-11 2.41E-10 28 123 "SLC2A11,BACH1,CCNT1,MYOM2,CCPG1,DNAJB5,SEC14L5,NOS1AP,DNAH9,ABCC5,MRNIP,COQ7,SCML2,SEC24B,FOXO3,MSANTD4,CPLX2,RBPJ,MMP17,SFR1,PIK3CD,PRKACB,MAPK9,ZFP30,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-573:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-11 9.17E-08 2.62E-11 2.41E-10 28 123 "ADARB2,DYNLL1,CANX,CLCN3,C3orf18,DMTN,FKTN,FGFR1,FICD,MARK1,SYT9,MTR,MYO5A,GPR137C,SLC25A23,PKN2,PLEKHB2,FNDC3A,ANKRD6,CPEB4,ARHGAP26,DDN,CAMSAP2,TBCEL,ZNF106,KAT6B,ZKSCAN5,PITPNB" MicroRNA "GTCAGGA,MIR-378:MSigDB" "GTCAGGA,MIR-378:MSigDB" MSigDB 1.72E-11 9.65E-08 2.76E-11 2.54E-10 18 50 "ABR,OGT,ATP2B2,FOXN3,CAMKK2,SHC3,NF1,NFIX,LRP12,CEP41,ROBO2,CCDC88A,KBTBD4,C3orf70,CRB1,TOM1L2,NSD2,VANGL2" MicroRNA hsa-miR-99a:mirSVR_highEffct hsa-miR-99a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.73E-11 9.74E-08 2.78E-11 2.56E-10 27 115 "KMT2C,NIPBL,CNTFR,SLC35F1,HS3ST2,SLC29A4,FGFR3,NKX6-2,KIAA1841,TUBGCP4,MIER3,KCNK2,MBNL1,CLDN11,PPP3CA,EPDR1,ERI2,RAVER2,AP1AR,CCDC88A,CAND2,PRRC2C,TCF7,SLC44A1,ZNF19,LMAN2L,WNK3" MicroRNA hsa-miR-3182:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-11 1.03E-07 2.93E-11 2.70E-10 23 84 "SPOP,TNRC6C,CASTOR3,AP1M1,NIPA1,CLCN3,RGS6,PLCXD3,RUSC2,SLC43A2,ZNF391,MRVI1,NR3C1,KCNN3,PDE3A,EPB41L4B,SEMA6D,SMARCE1,FAM126B,BDP1,FAM208A,SZT2,TPD52L2" MicroRNA hsa-miR-1207-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-11 1.03E-07 2.93E-11 2.70E-10 23 84 "ZNF578,CDC42,ARHGAP22,ENTPD4,CRY2,CSNK1E,PPP1R16B,KIAA0408,YTHDC1,REEP2,PCYOX1,ZFYVE27,NBL1,NLE1,ZMAT4,SETD5,ZFP30,GPRIN3,ZNF106,SMUG1,XKR7,URM1,MPPE1" MicroRNA hsa-miR-6072:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-11 1.03E-07 2.93E-11 2.70E-10 23 84 "C3orf14,CFAP410,CLTC,IGDCC3,ERBB2,MRPL37,ANKMY1,GCK,PCDH17,HMGB1,KCNN1,CTNNA3,HMGCLL1,TNPO2,NCR3LG1,PEX2,STX1B,TMEM178B,TNFRSF1B,VLDLR,DHX33,URM1,GAN" MicroRNA hsa-miR-1273:mirSVR_highEffct hsa-miR-1273:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.87E-11 1.05E-07 3.00E-11 2.76E-10 36 196 "LRRC7,CNIH2,SFMBT2,CACNB2,ARHGEF6,ERC2,ZEB2,ABCC5,SUGP2,PAN3,ZNF678,KCNJ16,ZNF667-AS1,MEF2C,MEIS1,NF1,NRCAM,PDE4B,XRN1,SIDT1,FIGN,RNF220,NUDT11,PBRM1,SLN,MYO16,TNIK,SOX10,DOK5,DDN,NCDN,DIP2A,CAMTA1,SLC44A1,HEY1,CPNE4" MicroRNA hsa-miR-6746-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-11 1.10E-07 3.14E-11 2.90E-10 37 206 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,APAF1,CDC14B,SFMBT2,ATM,ADGRB2,FMNL3,IPCEF1,TMEM170A,DNAL1,MRNIP,EN2,VPS26C,ZNF585B,ZNF589,MTHFD2,GJB1,BVES,NFIX,PDGFRA,QDPR,ALG9,GSTCD,PTGR2,SEPHS1,ARC,ASTN2,FAM208A,AKNA,CBX5,TPM3,TBC1D15,ZNF28" MicroRNA hsa-miR-1201:PITA hsa-miR-1201:PITA_TOP PITA 1.98E-11 1.11E-07 3.17E-11 2.92E-10 22 77 "ATP1A1,CD81,GAPVD1,FRMPD4,NYAP1,TENM1,UFM1,CAB39,ZNF638,CLVS2,MBNL1,MEIS1,TRHDE,SCHIP1,POU3F2,TEX2,ELOVL4,TTBK2,ZC3H4,SATB2,ZFPM2,ZIC1" MicroRNA hsa-miR-3619-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-11 1.12E-07 3.20E-11 2.95E-10 31 150 "ELFN2,CASKIN1,SFMBT2,PDXK,ZBTB10,LDLRAD4,TBPL1,CS,NCAN,SOCS5,RUBCN,HEYL,FGFR1,FAM49B,NPTN,DKK3,MTHFD2,GNAL,PPM1L,KCTD15,CNNM2,SCN4B,CPEB4,ERC1,GANAB,TPM3,LRTM2,RPL7L1,BCL2L13,VAV2,GDPD5" MicroRNA hsa-miR-7109-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-11 1.13E-07 3.21E-11 2.96E-10 28 124 "TRMT9B,PRX,ARHGDIA,BCL7A,METTL6,NEURL1,CLU,ZNF385A,CRMP1,PYGO1,EIF4G1,ERBB2,CELF1,MTHFD2,GFER,PRRC2B,PLEC,SDK2,SPATA6,DIRAS2,HSD11B1L,ZFP30,SMTN,NMNAT2,USP22,RBFOX2,MGAT5B,MEAF6" MicroRNA hsa-miR-32-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-11 1.13E-07 3.21E-11 2.96E-10 28 124 "CC2D2A,USP37,KIAA1614,FAM169A,MYADM,NCALD,MED12L,CELF1,PPARGC1A,KIAA1958,KIF3A,C5orf24,RBPJ,PAXBP1,NCOA7,GPSM2,FAT3,WDR37,BTBD3,SMTN,NAXD,PEG10,TCF7L2,VLDLR,WNK1,MAP3K12,HNRNPA3,ZDHHC20" MicroRNA hsa-miR-3668:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-11 1.13E-07 3.22E-11 2.96E-10 21 70 "BACH1,SRSF11,CLCN3,ACBD5,ANKRD46,ZNF391,MTHFD2,SESN1,TNRC6A,NUDT21,ZNF678,CCDC80,MYO5A,PRKAB2,ZIK1,FIGN,PRIMA1,CSRNP3,CHD9,BTBD3,HNRNPA3" MicroRNA hsa-miR-6131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.03E-11 1.14E-07 3.25E-11 2.99E-10 39 226 "TMEM132B,CCAR2,TMEM184B,BAG4,SEC14L5,MYADM,FGFR1OP2,PLEKHM1,RABGAP1L,DNAJB6,FEM1B,FAXC,CRCP,FERMT2,GRID1,NR3C1,DDX19B,KCNN3,CYP27C1,MAN2A2,MYO5A,MYO6,NEUROD1,NUCB1,ZNF426,ZMAT4,C12orf49,SGSM1,NUBPL,ANKRD36,FAM126B,KIF1B,ZBTB43,SSTR2,CYB561A3,ZNF34,SGK3,ZNF70,PIANP" MicroRNA hsa-miR-18b-5p:Functional MTI Functional MTI miRTarbase 2.15E-11 1.21E-07 3.44E-11 3.16E-10 27 116 "AS3MT,RNF157,PTCHD1,TAOK1,ATM,CA12,TBPL1,DCAF4,DCAF8,LIN54,TOMM20,KLHL3,F3,WAC,ZNF585B,NCKAP1,GNAS,AGFG1,IGF1,ZNF678,MBD1,PCDH9,PDE4D,PSAT1,CRB1,ITM2C,RNF146" MicroRNA hsa-miR-6747-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-11 1.21E-07 3.44E-11 3.16E-10 27 116 "MARCH4,ANK1,ARHGDIA,CRLF1,ZNF385A,PYGO1,IP6K1,DBT,PLEKHM1,ELN,GLI2,PRRC2B,GRIN2D,MDM4,MPP2,MYO5A,EPN1,SPATA6,MAPK10,SETD5,KLHDC8A,FOXRED2,ATXN2,CAMTA2,UBTF,RICTOR,ZDHHC20" MicroRNA hsa-miR-3978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-11 1.21E-07 3.44E-11 3.16E-10 27 116 "AK2,FOXK1,HAPLN1,CTNND1,DCAF8,KIAA0513,TMEM170A,ABCC9,EGR3,C8orf37,SUCO,SYNCRIP,GNAS,CECR2,PLD5,NASP,GPR137C,PDPK1,PLEC,PSAT1,PGBD4,ATXN7,CPEB3,BCAN,SLC8A1,TUBB2A,HNRNPA3" MicroRNA hsa-miR-1268:mirSVR_highEffct hsa-miR-1268:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.21E-11 1.24E-07 3.53E-11 3.25E-10 29 133 "CSMD3,UNC5A,CDK10,CDK5R2,LETMD1,TRIM69,FRMPD4,MYEF2,DDX46,TMCC2,SEMA3D,CGREF1,STMN2,GRM7,FAM107A,KCNA2,KIT,LMO2,A2ML1,TMEM260,ARHGEF10L,RNF220,TCP11L1,ITSN1,FAM214B,NKAIN2,MAPK8IP3,SEPT3,PRMT8" MicroRNA hsa-miR-4693-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.23E-11 1.25E-07 3.55E-11 3.27E-10 26 108 "KLHL32,PPFIA4,TMEM184B,CSF1,ARHGEF4,MRO,BVES,SYNPO,NKD1,SLC35G1,ZFYVE27,CHIC1,SAMD5,NUCB2,PFKFB2,OLA1,PTPA,UHRF1BP1,NKAIN1,RAB5B,MYH14,NCBP3,TMCC1,TMEM136,SLC19A3,TMPRSS5" MicroRNA hsa-miR-466:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-11 1.30E-07 3.69E-11 3.40E-10 33 169 "TAOK1,STX16,BACH1,BAG4,CPEB2,SORBS3,CERCAM,TUBA1B,SYT17,COPS8,GLI2,DIDO1,NR3C1,C5orf24,ZNF678,KLHL23,KIF5C,SFXN5,SYTL4,NEXMIF,NAP1L1,ZNF827,PIK3R1,PURG,PPP2R5E,PROX1,C12orf49,ZNF415,NSFL1C,SIK3,HHIP,NR2C2,UBTF" MicroRNA hsa-miR-492:PITA hsa-miR-492:PITA_TOP PITA 2.39E-11 1.34E-07 3.81E-11 3.51E-10 23 85 "RALGAPA1,SEMA4G,NCOA1,ARHGEF4,DBN1,C2CD2L,G3BP2,DYRK1A,ZCCHC17,RNF165,MAT2A,NPTX1,IGSF11,KCTD15,ROBO2,CSRNP3,TRA2B,CPEB3,NCDN,SYN2,SLC44A1,THRA,SMARCAD1" MicroRNA hsa-miR-3194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.39E-11 1.34E-07 3.81E-11 3.51E-10 23 85 "SFMBT2,PRX,LDLRAD4,NEURL1,STOML1,TMEM184B,G3BP2,KBTBD11,TOM1,APC2,ANKMY1,CELF1,LYVE1,STARD3,ATCAY,NODAL,PRRT2,KCNIP2,FAM192A,ZBTB43,DIP2A,AJAP1,MEAF6" MicroRNA hsa-miR-5580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-11 1.42E-07 4.03E-11 3.72E-10 18 51 "ADAR,C6orf89,USP37,BACH1,ADGRB2,ARHGAP22,CSF1,MICAL2,RAB30,FICD,ADAM22,NFIX,NPTX1,MINDY2,ZNF793,PTGR2,MAPK8IP3,ZNF708" MicroRNA hsa-miR-3664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-11 1.43E-07 4.04E-11 3.72E-10 36 198 "TEX22,ESYT2,ZNF555,COL9A2,IGDCC3,GAPVD1,DBT,SGSM2,DCTN4,TUBD1,COQ7,ZNF549,KATNAL1,CNDP1,LILRA2,KAT7,NKD1,KLHL23,MOG,ZNF713,OLA1,CAMKV,PPP2R5C,BCAS3,PIGG,ZYG11B,ELP2,NCBP3,IL17RB,HSPA4L,ANKRD36,DIP2A,ADAMTS17,ZNF106,WRN,RNF170" MicroRNA "GCAAGGA,MIR-502:MSigDB" "GCAAGGA,MIR-502:MSigDB" MSigDB 2.61E-11 1.47E-07 4.16E-11 3.83E-10 20 64 "OGT,RIMS4,DAPK1,KLHL3,SRGAP3,ING4,PAN3,TESK2,SGIP1,AKAP3,DOT1L,ZMAT1,RAB30,KITLG,MID1,MXI1,PDPK1,PLP1,ZFP91,RIMBP2" MicroRNA hsa-miR-609:PITA hsa-miR-609:PITA_TOP PITA 2.61E-11 1.47E-07 4.16E-11 3.83E-10 20 64 "ARID1A,NRXN2,ZNF385A,TMEM164,TMEM107,USP21,TTBK1,GRIK2,KLF12,MEF2C,PDPK1,TMEM145,KIRREL1,CCDC88A,TMCC1,PDZRN3,NCDN,SIRT1,AMACR,ZIC2" MicroRNA hsa-miR-604:PITA hsa-miR-604:PITA_TOP PITA 2.65E-11 1.49E-07 4.22E-11 3.89E-10 14 29 "BSN,CAMK2G,DCLK1,ZNF521,RIMS4,TAOK3,GRIA4,GRIK5,CAMK2N2,MSI1,MED1,ARX,PITPNB,PIANP" MicroRNA hsa-miR-3925-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.66E-11 1.50E-07 4.24E-11 3.90E-10 27 117 "PHF12,IGDCC4,CLDN10,BAG4,BLOC1S6,G3BP2,SLC37A3,CELF1,ST6GALNAC3,ATP8A2,GFRA1,CRCP,TNRC6A,GPM6B,GRIK2,PLD5,CNOT4,ZIK1,NWD1,MORC4,RNASEL,ELP2,RUFY2,NR2E1,PRMT8,TSN,SPIRE1" MicroRNA hsa-miR-6830-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-11 1.50E-07 4.24E-11 3.91E-10 24 93 "TTYH1,TNRC6C,BAG4,PITPNM3,DPP6,FRY,PHF20L1,ELAVL3,GATM,PCDH17,KAT7,RASSF8,NEGR1,KIAA1755,KCNN3,CD200,KSR2,GLIPR1L2,SNX10,NAXD,SMOC1,TNR,ZNF711,PMEPA1" MicroRNA "ATGCTGG,MIR-338:MSigDB" "ATGCTGG,MIR-338:MSigDB" MSigDB 2.78E-11 1.56E-07 4.43E-11 4.08E-10 26 109 "ESYT2,SEMA6A,MAP4K3,ZBTB10,ATP2B1,N4BP2L1,SRGAP3,FRY,KCND2,KCNMA1,MYCN,NOVA1,SEPT4,TMEM255A,ARHGEF10L,ZFHX4,FBXW7,SEMA6D,CPEB3,SMTN,MYCBP2,CLASP2,LARP4,SYN2,AP4E1,TBC1D15" MicroRNA hsa-miR-4302:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-11 1.58E-07 4.48E-11 4.13E-10 30 143 "ELFN2,SLC24A4,SFMBT2,LDHD,EVI5L,SEC16A,ABI2,ELN,C8orf37,CELF1,GCK,MAT2A,POLR2F,ZNF844,QDPR,SLC25A36,KIAA0895L,ATXN1,SGK1,SLC2A5,PEX26,ZFP1,CXXC4,ZNF415,ITPRID2,PRRC2C,DDHD1,CCDC14,ZNF24,ZNF195" MicroRNA hsa-miR-3121-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-11 1.58E-07 4.48E-11 4.13E-10 30 143 "SDE2,WDR35,DPY19L3,CPS1,TENM4,PDE4DIP,DGKB,FEM1B,SH3GLB1,ELAVL4,SYNCRIP,ST6GALNAC3,FUT9,GABRB1,GPR75,TNRC6A,RASSF8,AGFG1,ZIC5,KITLG,TMEM231,ALG9,NCBP3,PPP1R9A,ATP11A,TAL1,CAMSAP2,TPD52,TUBB2A,RPL7L1" MicroRNA hsa-miR-5584-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.82E-11 1.58E-07 4.48E-11 4.13E-10 30 143 "RNF157,OGT,PHF12,APP,LDHD,CTNND1,TM9SF4,ST8SIA3,WAC,GTF2IRD2,CAMKK2,GABRA5,TNRC6A,GNG3,STMN1,SCAMP5,NPTX2,ZNF827,TNPO2,CNNM2,SLC25A36,LHPP,SSTR1,ZSCAN29,ARL10,UBE2H,MGAT5B,URM1,ITM2C,HNRNPA3" MicroRNA hsa-miR-4795-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.86E-11 1.61E-07 4.55E-11 4.19E-10 31 152 "ADARB2,AK2,TAOK1,PHF12,DYNLL1,DIRAS1,NRXN3,PHC2,EFNA3,C3orf18,DMTN,FKTN,FOXO3,LILRA2,FICD,SYT9,MYO5A,SLC25A23,ZNF426,PKN2,PLEKHB2,SCN2B,CPEB4,DDN,CAMSAP2,TBCEL,ZNF106,KAT6B,UBTF,PITPNB,FXR1" MicroRNA hsa-miR-6752-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-11 1.69E-07 4.78E-11 4.41E-10 28 126 "RNF150,SORCS2,SEMA4G,LDLRAD4,CACNA1A,AKAP5,RTTN,CRY2,G3BP2,FAXC,SRCAP,TXNL4A,RAB40B,GPD1,FAM107A,KCNQ3,MAN2A2,NFIX,KCNK10,CAMKV,KCTD15,DPF2,GALNT10,TMEM151B,GALNT17,DAAM2,TPM4,VANGL2" MicroRNA hsa-miR-1238-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-11 1.83E-07 5.17E-11 4.76E-10 29 135 "GRAMD1B,TNRC6C,APP,SLC7A14,ATP2B3,LDLRAD4,RUNX1T1,SLC22A6,PLCXD3,DPYSL2,TMTC1,SLC43A2,SCML2,GABRA5,GRID1,GRIK3,PTGDR2,MAT2A,MBNL1,MID1,NFYA,ZNF844,ELP2,NLGN1,SLIT1,TGFBR3,TFIP11,FAM13C,FRMD6" MicroRNA hsa-miR-100:mirSVR_highEffct hsa-miR-100:mirSVR_conserved_highEffect-0.5 MicroRNA.org 3.29E-11 1.85E-07 5.22E-11 4.81E-10 27 118 "CACNA1D,NIPBL,NCOR2,MYEF2,HS3ST2,SLC29A4,EML1,FGFR3,NKX6-2,TUBGCP4,RNF165,MIER3,KCNK2,MBNL1,CLDN11,PPP3CA,SIDT1,RAD51D,ERI2,RAVER2,AP1AR,CAND2,PRRC2C,SLC44A1,ZNF19,DHX33,WNK3" MicroRNA hsa-miR-6866-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-11 1.92E-07 5.41E-11 4.98E-10 24 94 "ADORA3,SPOP,AQP6,CACNA1A,VXN,SLC16A4,SEC31B,ELMSAN1,G3BP2,TMTC1,PLEKHA1,WASF3,KIF3A,KLHL23,MBNL1,C10orf105,CEP97,GTDC1,UBR7,ATXN1,GALNT10,MEAF6,PRDM2,KAT6A" MicroRNA hsa-miR-6888-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.42E-11 1.92E-07 5.42E-11 5.00E-10 31 153 "CDC14B,SFMBT2,ARSE,ZNF555,LRIG1,PITPNM3,PLCXD3,GAPVD1,RASSF2,SGSM2,KATNAL1,GABRA1,TRAF3IP2,FAXC,KLF12,SYTL4,LSAMP,KSR2,OLR1,GLIPR1L2,PDE3A,IL17RB,NAXD,BDP1,EMC1,ADAMTS17,EXOC7,SZT2,SLC38A1,NAV2,ZDHHC20" MicroRNA hsa-miR-4268:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.47E-11 1.95E-07 5.50E-11 5.06E-10 22 79 "RNF157,TBC1D14,NDST3,CSNK1E,RUSC2,KIAA0319,PLEKHO1,AMOTL2,RAPGEF6,SRRM4,POLL,HMX1,TLX1,HMGCLL1,TNPO2,TRIM67,TMEM178B,LEFTY2,CBX5,CCDC14,UPF3A,WNK1" MicroRNA hsa-miR-144-3p:Functional MTI Functional MTI miRTarbase 3.52E-11 1.98E-07 5.58E-11 5.14E-10 37 210 "ARID1A,TAOK1,APP,STX16,CPS1,SPATA2,ZEB2,ZC3H11A,RAB39B,GOLGA7,ACSL4,STAMBP,DIDO1,GRIK3,NR3C1,DIPK1A,LIFR,MBNL1,MKLN1,MYCN,MYO5A,NFE2L2,ZNF827,TUG1,OXR1,FBXW7,ATXN1,FNDC3A,ATF7IP,ANKRD12,ZEB1,TGFBR3,CADM1,RPL7L1,WNT7A,WRN,WNK1" MicroRNA hsa-miR-423-3p:Functional MTI Functional MTI miRTarbase 3.52E-11 1.98E-07 5.58E-11 5.14E-10 39 230 "KIDINS220,APP,SFMBT2,KIF1A,LURAP1,ARHGEF2,FADS2,SH2B1,APPL1,PUM1,LYPD1,DDX46,POM121,REEP2,SCML2,CEP78,GLDC,ZFYVE27,NPTX2,SLC11A2,PKM,MAPK3,MRPS18A,SETD5,ROBO1,MCMBP,RXRA,ATXN7,SHMT2,ARFGAP1,LARP4,ZC3H4,SZT2,NACC2,TRPM2,TBC1D15,NSD2,POLR3H,WNK1" MicroRNA hsa-let-7a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.52E-11 1.98E-07 5.58E-11 5.14E-10 25 102 "ARID1A,USP28,APP,MAP7,ABI2,WAC,DLC1,FYN,GABRB3,KAT7,BACH2,HMGB1,DOCK7,KCNB1,NFIX,OLR1,ZFYVE21,TRA2B,FNDC3A,PRRC2C,TMEM136,SLC44A1,ARL10,CADM1,URM1" MicroRNA hsa-miR-524-3p:mirSVR_highEffct hsa-miR-524-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.68E-11 2.07E-07 5.83E-11 5.37E-10 28 127 "NUMB,MICAL2,ARHGAP32,GOLT1B,EBF1,FCGRT,ATP2C1,CRCP,COPS8,AGBL5,AQP11,MTR,NTRK3,GPR88,MAPKAP1,RASGRF2,PRRT2,GTDC1,SEC61A2,KIAA0895L,HSD11B1L,SH3BGR,SLIT1,ZC3H13,DDN,ADGRL3,MTMR14,CSDE1" MicroRNA hsa-miR-5010-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-11 2.23E-07 6.29E-11 5.80E-10 32 163 "TNRC6C,CACNG1,CCPG1,COL9A2,ACBD5,CLOCK,CSNK1G3,NCAN,JAKMIP2,ZC3H11A,DMD,EPHA5,FGF14,DOT1L,CBX1,AP4S1,SCRT2,IPO5,HECTD2,MAOB,CCDC80,HS6ST3,PDPK1,PLP1,REV3L,CLIP1,ATXN1,MPRIP,ASTN2,ZEB1,VSNL1,PORCN" MicroRNA hsa-miR-4496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.05E-11 2.27E-07 6.41E-11 5.90E-10 27 119 "AXIN2,NUMB,ABCG2,CRY2,SOCS5,SEC14L5,KIAA0408,SEZ6,HSPA12B,DLC1,CELF1,TVP23A,KIF3A,TJAP1,MKLN1,NFIA,AMER2,SEMA6D,LGI3,IQSEC2,DDN,NFASC,DIP2A,SYPL1,TPM4,RTN4,SPATA13" MicroRNA hsa-miR-4645-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.07E-11 2.29E-07 6.44E-11 5.93E-10 30 145 "LTBP4,APAF1,DNAH17,DDR1,NUMBL,NCAN,ANKMY1,TOMM40L,POLR1B,C15orf41,FUT10,GPR26,GRK4,RNF165,IRAK3,HMGB1,KCNH1,KCNJ11,CREG2,QDPR,ELP2,PEAR1,SH3BP2,R3HDM2,PEX26,TRIM67,ARC,SLC37A2,RFTN2,AMZ1" MicroRNA hsa-miR-4786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-11 2.42E-07 6.83E-11 6.29E-10 26 111 "SFMBT2,ATP2A2,DGKI,COL9A2,HEPH,TOM1,FSD1L,CACNG7,ZNF391,FOXO3,ATP13A4,CYP46A1,GPER1,MAOB,ZNF426,LGR4,KCNIP2,NCBP3,R3HDM2,MPRIP,SEPT3,SYT11,ANKRD24,TPM3,ZNF225,FBXO36" MicroRNA hsa-miR-3149:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.45E-11 2.50E-07 7.05E-11 6.49E-10 33 173 "ARID1A,RNF150,ZMYM4,PUM1,HDAC4,EIF5,C8orf37,EPB41L1,PDLIM5,ZNF276,PTPRT,SLC2A6,DDX19B,MIER3,HNF4G,NEUROD2,OPCML,PAK3,PLCL1,GDPD1,NWD1,ZYG11B,FIGN,FAM161B,RUFY2,TMCC1,ZEB1,GPRIN3,FAM200B,SSBP2,ZNF711,ZNF195,LINC00632" MicroRNA hsa-miR-342-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-11 2.52E-07 7.08E-11 6.52E-10 28 128 "CRLF1,ZNF385A,MICAL2,IP6K1,PLEKHM1,ELN,RNPS1,GLI2,PRRC2B,MDM4,MPP2,EPN1,SPATA6,MAPK10,PTPRG,RIPOR1,KIF7,KLHDC8A,ROBO2,MCMBP,FOXRED2,ATXN2,SMARCA4,NMNAT2,PRRC2C,ANKRD12,UBTF,VANGL2" MicroRNA hsa-miR-95-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-11 2.52E-07 7.08E-11 6.52E-10 28 128 "WDR35,TNRC6C,ARHGDIA,PTBP2,SPAG9,DGKB,YTHDC1,CPEB2,AASDH,EN2,SUCO,NCKAP1,MMADHC,CRCP,GLI2,RAPGEF1,USP51,OCRL,P2RY1,TMEM200C,MRAS,LIMCH1,FAM126B,ZBTB43,SYT11,PSD3,RPL7L1,ZNF711" MicroRNA hsa-miR-6515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.48E-11 2.52E-07 7.08E-11 6.52E-10 28 128 "ADCY5,CASKIN1,KIF6,BTF3L4,CS,RASSF2,SPATA2,DMTN,RTN3,FGFR1,DOT1L,SRCAP,NEGR1,SESN3,NFIX,PKM,POLG,RAB5B,SETD5,KIAA0895L,AMBRA1,GPRIN3,NACC2,ZFP91,WBP2,TUBB2A,CLDND1,SMARCAD1" MicroRNA "GTGTCAA,MIR-514:MSigDB" "GTGTCAA,MIR-514:MSigDB" MSigDB 4.51E-11 2.54E-07 7.14E-11 6.57E-10 19 59 "TAOK2,NRXN3,ARFGAP2,NR3C1,GRM8,NCOA7,PTPRG,RAB3A,BAALC,SCN3A,SYT11,ARHGEF9,TAL1,TRIM2,TCF12,EIF4ENIF1,ZIC1,NAV3,ST8SIA2" MicroRNA "TTGGGAG,MIR-150:MSigDB" "TTGGGAG,MIR-150:MSigDB" MSigDB 4.55E-11 2.56E-07 7.19E-11 6.62E-10 22 80 "PKP4,IFFO1,MYADM,C2CD2L,KLHL3,POM121,DYRK1A,PLXNC1,TESK2,GABRG2,GLDC,ICA1,IGF1,KCNN3,PRRT2,ATAT1,TMCC1,FBXW11,TRPS1,ZNF189,MAP3K12,NAV2" MicroRNA hsa-miR-1296-5p:Functional MTI Functional MTI miRTarbase 4.97E-11 2.79E-07 7.85E-11 7.23E-10 27 120 "BRAP,MTUS1,TXNDC16,BCL2L2,APPL1,DCTN1,ERBB2,ZNF549,TOMM40L,RNPS1,NUDT21,CECR2,UBE2QL1,IPO5,LIFR,TBC1D25,POLR2F,SH3TC2,ZMAT4,RTKN,SFPQ,NFASC,MPRIP,GANAB,TMPO,ANKRD24,AAAS" MicroRNA hsa-miR-518a-3p:PITA hsa-miR-518a-3p:PITA_TOP PITA 5.48E-11 3.08E-07 8.65E-11 7.96E-10 16 41 "PLEKHG5,ZNF608,NRXN1,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,WNK1,SOCS4" MicroRNA hsa-miR-518c:PITA hsa-miR-518c:PITA_TOP PITA 5.48E-11 3.08E-07 8.65E-11 7.96E-10 16 41 "PLEKHG5,ZNF608,NRXN1,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,WNK1,SOCS4" MicroRNA hsa-miR-518b:PITA hsa-miR-518b:PITA_TOP PITA 5.48E-11 3.08E-07 8.65E-11 7.96E-10 16 41 "PLEKHG5,ZNF608,NRXN1,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,WNK1,SOCS4" MicroRNA hsa-miR-518f:PITA hsa-miR-518f:PITA_TOP PITA 5.48E-11 3.08E-07 8.65E-11 7.96E-10 16 41 "PLEKHG5,ZNF608,NRXN1,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,WNK1,SOCS4" MicroRNA hsa-miR-518d-3p:PITA hsa-miR-518d-3p:PITA_TOP PITA 5.48E-11 3.08E-07 8.65E-11 7.96E-10 16 41 "PLEKHG5,ZNF608,NRXN1,SOCS5,AGAP3,ZHX1,NEXMIF,ZNF827,RBBP8,MCF2L,TSN,PLEKHH2,KCNK12,CELF4,WNK1,SOCS4" MicroRNA hsa-miR-4735-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.51E-11 3.10E-07 8.69E-11 8.01E-10 24 96 "AS3MT,RNF157,PTCHD1,TAOK1,ATM,CA12,TBPL1,DCAF4,DCAF8,LIN54,TOMM20,KLHL3,F3,ZNF585B,GNAS,AGFG1,ZNF678,MBD1,PCDH9,PDE4D,PSAT1,CRB1,ITM2C,RNF146" MicroRNA hsa-miR-708-5p:Functional MTI Functional MTI miRTarbase 5.55E-11 3.12E-07 8.75E-11 8.06E-10 25 104 "PLEKHG5,KMT2C,CNTFR,NOS1AP,CTIF,ZEB2,TUBB4A,PCYOX1,AHDC1,PRRC2B,RNF165,KCNH2,NNAT,NRCAM,KLHL11,DRAXIN,SEC14L1,MYH15,IQSEC2,FAM168A,THRA,ZFP91,TUBB2A,PRDM2,PIANP" MicroRNA hsa-miR-6743-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.55E-11 3.12E-07 8.75E-11 8.06E-10 25 104 "GPRIN1,ELFN2,SYT13,OGT,PHF12,ARHGDIA,CAMK2A,NOS1AP,SPATA2,AHDC1,CRCP,POLL,B4GALNT4,MDM4,HS6ST3,PKD1,MTRF1L,TMCC1,NSD1,PUM2,TMPRSS5,TUBB2A,RPL7L1,URM1,WIPF2" MicroRNA hsa-miR-6879-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-11 3.22E-07 9.02E-11 8.31E-10 29 138 "XKR4,ATP1B3,BSN,NUMBL,TM9SF4,CTIF,DNM2,SH3GLB1,AMOTL2,SRCAP,GJB1,KCNH1,PPM1L,NEUROD2,NLE1,PACSIN1,C1orf109,SH3TC2,ZMAT4,SLC6A9,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,TMPRSS5,PMEPA1,GAN" MicroRNA hsa-miR-4756-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-11 3.22E-07 9.02E-11 8.31E-10 29 138 "INTS2,BCAS1,CLDN10,PLAA,DNAH9,DNAJB6,TUBB4A,TRMO,HHIPL1,CRCP,COPS8,TNRC6A,KIAA1958,KAT7,KIAA1755,IBA57,CREG2,SYT9,OPHN1,PDPK1,NLE1,KANSL1,RNASEL,SGK1,ZFP30,PEX26,FAM126B,PDZD2,MEAF6" MicroRNA hsa-miR-6835-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-11 3.22E-07 9.02E-11 8.31E-10 29 138 "KIAA0408,DCAF8,ELMSAN1,EFNA3,F3,CELF1,CIT,ELOVL5,SYNPO,METTL21A,CCDC80,NEUROD1,NFYA,PDE4D,PDPK1,PLEC,CRLS1,KLHL11,ROBO1,SEC31A,FAM126B,HECW1,NXT2,KIAA0930,USP22,TPD52,ZXDA,URM1,NAV2" MicroRNA hsa-miR-494-3p:Functional MTI Functional MTI miRTarbase 5.73E-11 3.22E-07 9.02E-11 8.31E-10 29 138 "ELFN2,ARHGAP5,ARNTL,CNR1,EN2,SYNCRIP,NPTN,PRRC2B,CREG2,ARHGAP12,TM6SF1,MDM4,MINDY2,CEP97,ZNF532,TMLHE,ATXN1,SLC8A1,FNBP1,ITPRID2,SS18,AJAP1,TMEM178B,ZEB1,TMEFF2,ZNF24,EVI5,HNRNPA3,SPATA13" MicroRNA hsa-miR-6715b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.73E-11 3.22E-07 9.02E-11 8.31E-10 29 138 "APAF1,FOXK1,NUMBL,DNAH9,TUBD1,IGSF6,TMEM132C,FDFT1,POLR1B,GABRB1,TXNL4A,B4GALNT4,ZIC5,KCNH1,CCDC80,NOS1,RMI1,SBF1,SH3BP2,R3HDM2,RUFY2,UNC5B,INKA2,GALNT17,TRPS1,TSN,RPL7L1,SIGLEC10,MVB12B" MicroRNA hsa-miR-3120-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.75E-11 3.23E-07 9.05E-11 8.34E-10 31 156 "CDC14B,ARSE,ZNF555,PITPNM3,PLCXD3,GAPVD1,RASSF2,SGSM2,KATNAL1,GABRA1,TRAF3IP2,POLL,SYTL4,LSAMP,MDM4,N6AMT1,KSR2,OLR1,GLIPR1L2,PDE3A,PTPA,IL17RB,URGCP,RUFY2,NAXD,BDP1,EMC1,ADAMTS17,EXOC7,NAV2,ZDHHC20" MicroRNA hsa-miR-3190-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.75E-11 3.23E-07 9.05E-11 8.34E-10 31 156 "ARID1A,ADCY2,TAOK1,PDXK,ALDH4A1,DPY19L3,LDHD,CANX,SRSF11,ACBD5,KIAA0040,FAM131B,C8orf37,WAC,CRCP,GPT2,GRIN2D,FICD,ZIC5,KCNJ10,PACSIN1,PPP2R5C,ZNF621,TRIM2,NSD1,ZNF106,SMUG1,BCL2L13,ZXDA,SSPN,NETO2" MicroRNA hsa-miR-3681-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-11 3.26E-07 9.12E-11 8.40E-10 40 244 "SDE2,ADD1,FZD9,TAOK1,GPAM,CANX,CCNT1,ZNF385A,PNKD,CREB5,RGS6,LONRF1,LIN54,SEC16A,KBTBD11,NR1D2,EIF5,EN2,TOMM40L,POLR1B,SUCO,TPPP,KAT7,SLC6A17,LIFR,MKLN1,PDE3A,PKD1,SDK2,RETREG2,ZYG11B,R3HDM2,ZFP1,WDTC1,PEG10,TROVE2,MPRIP,FRYL,TGFBR3,WRN" MicroRNA hsa-miR-216a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.80E-11 3.26E-07 9.12E-11 8.40E-10 40 244 "SDE2,ADD1,FZD9,TAOK1,GPAM,CANX,CCNT1,ZNF385A,PNKD,CREB5,RGS6,LONRF1,LIN54,SEC16A,KBTBD11,NR1D2,EIF5,EN2,TOMM40L,POLR1B,SUCO,TPPP,KAT7,SLC6A17,LIFR,MKLN1,PDE3A,PKD1,SDK2,RETREG2,ZYG11B,R3HDM2,ZFP1,WDTC1,PEG10,TROVE2,MPRIP,FRYL,TGFBR3,WRN" MicroRNA hsa-miR-30a-3p:Functional MTI Functional MTI miRTarbase 5.96E-11 3.35E-07 9.36E-11 8.62E-10 35 194 "CDK13,CACNA1E,ENTPD4,MAML1,YTHDC1,FAM107B,DYRK1A,EIF1,CAMSAP1,NPTN,GABRA2,MTHFD2,SULT1C4,COPS8,GNAL,KCNN3,STMN1,MDM4,KCTD6,NAP1L1,NUCB1,PCSK2,EPB41L4B,SH3TC2,CCDC25,SCP2,GALNT10,CLSTN1,SLC1A2,NBPF1,FAM126B,STAU1,TUBB2A,ATP6V0E2,TUBA1A" MicroRNA hsa-miR-7162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-11 3.45E-07 9.64E-11 8.88E-10 33 175 "ARID1A,APAF1,CCNT1,MYOM2,SUMF2,GREB1,LONRF1,TMTC1,IRAK4,TOMM40L,CELF1,CRCP,LUZP2,LILRA2,MDM4,MMP17,BLOC1S2,THYN1,SFR1,NUCB2,OPRL1,PIK3CD,ALG9,ATXN2,PEG10,KIF1B,MCF2L2,NEK4,SYT1,SLC19A3,TUBB2A,WIPF2,ZDHHC20" MicroRNA hsa-miR-490-3p:Functional MTI Functional MTI miRTarbase 6.20E-11 3.48E-07 9.73E-11 8.96E-10 37 214 "XKR4,TRMT9B,CDC14B,ASPA,MTMR3,FOXK1,CBFA2T2,MYOM2,LONRF2,CDR1,COL9A2,GREB1,SYT15,RASA4,IRAK4,MRNIP,ZNF549,RCSD1,TRMO,ERGIC3,KBTBD12,CAB39,DISC1,LILRA2,DDX19B,SCRG1,RBPJ,IBA57,PPM1L,MYO5A,QDPR,PGBD4,CDK19,NFASC,FAM208A,CLASP1,BHLHB9" MicroRNA hsa-miR-6771-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.27E-11 3.52E-07 9.84E-11 9.06E-10 41 255 "KIAA1324,SEMA4G,DOCK11,MYOM2,ATRNL1,PITPNM3,CTH,KIAA0513,CEP170,E2F6,MRO,ANKMY1,BRPF3,NCKAP1,GLUL,KIAA1958,LUZP2,PRRC2B,GRK4,CACFD1,AGBL5,IGF1,KCNJ4,SAMD5,CCDC80,SLC11A2,BEST3,FAT3,PTPRB,RAB5B,ARID4A,C12orf49,RORB,HOGA1,MAGI3,IQSEC2,SYPL1,ALG1,ERCC6L2,TBC1D15,SF1" MicroRNA "TATCTGG,MIR-488:MSigDB" "TATCTGG,MIR-488:MSigDB" MSigDB 6.29E-11 3.53E-07 9.88E-11 9.10E-10 19 60 "PCDH19,MIER1,TMEM263,CDK13,NCOA1,ATP1A1,NRXN3,CNN3,CREM,RCAN2,CAB39,LIFR,PDE4D,FBXW7,CPEB3,SATB2,RPGRIP1L,ZFP91,NAV3" MicroRNA hsa-miR-2355-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.29E-11 3.53E-07 9.88E-11 9.10E-10 19 60 "SERPINA3,RNF157,ATP2B3,CA12,CHD5,UBXN2A,E2F6,CELF1,GABRB1,NR3C1,IL6ST,KCNJ10,SHC3,SEPT4,CSRNP3,ZMAT3,NR2E1,VLDLR,MVB12B" MicroRNA hsa-miR-2355-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.59E-11 3.70E-07 1.03E-10 9.52E-10 34 185 "RALGAPA1,TAOK1,GYG2,CACNA1A,LURAP1,HINFP,CTNND1,CCDC144A,RIMS3,SIRPA,FAM13A,APH1A,UFM1,ST6GALNAC3,NEURL4,DKK3,ZNF638,ARHGAP19,BACH2,POU6F1,PPP2R5E,GTDC1,PTGR2,ZFP30,NAXD,ZFP1,ANKRD36,ZNF415,CLUAP1,INKA2,ADAMTS17,TBX15,DOK6,ZNF138" MicroRNA hsa-miR-1307:mirSVR_lowEffct hsa-miR-1307:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 6.59E-11 3.70E-07 1.03E-10 9.52E-10 34 185 "AMPD2,SUGT1P4-STRA6LP-CCDC180,ATP2B3,CALB2,CABP1,CSNK1G3,RASSF2,TM9SF4,TOMM40L,NSG2,DCLK2,GNAO1,STON1,GPER1,GRIA1,GRIA2,RNFT2,AGBL5,NRGN,NUCB2,SMIM7,PLXNB3,C11orf49,PPP3CB,NDUFS7,WBP1L,SOX2,C11orf87,AJAP1,ADGRL3,TMPO,PIK3R5,SLC38A1,STMN4" MicroRNA hsa-miR-6734-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-11 3.71E-07 1.04E-10 9.54E-10 28 130 "ELFN2,PNMA8B,OGT,ARRB2,ASPH,ASTN1,FOXK1,ARHGEF2,EVI5L,NOS1AP,RPS6KL1,ABCC5,EIF1,SEPT9,GSN,RNF165,MMP17,NDUFA5,OLR1,PTPRE,SLC2A5,TAB2,SMOC1,SEPT8,AJAP1,CBX5,TPD52,RPL7L1" MicroRNA hsa-miR-1251:PITA hsa-miR-1251:PITA_TOP PITA 6.66E-11 3.74E-07 1.04E-10 9.61E-10 23 89 "SDE2,FMNL2,GPR158,APBB2,SLC25A14,VXN,TMEM257,CBARP,LHX2,CTNND1,MAML1,RNF165,GYG1,CELF3,KLF12,HLF,IGF1,FAM120C,ENHO,TPD52,TPM3,TMEM237,NAV3" MicroRNA hsa-miR-587:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.93E-11 3.89E-07 1.09E-10 1.00E-09 25 105 "AK2,ZBTB10,RUNX1T1,SEPT7,CDH2,HDAC4,CEP170,RCAN1,LYVE1,EML4,AFF1,ZDHHC22,NCR3LG1,ZDHHC14,MSANTD2,CSRNP3,DDHD2,TBCEL,USP22,C5orf64,NR2C2,RUNDC3B,VSNL1,DHX33,JMJD1C" MicroRNA hsa-miR-889-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.93E-11 3.89E-07 1.09E-10 1.00E-09 25 105 "FMNL2,MARCH3,ABCG2,UBXN2A,USP6NL,PYGO1,DCC,YTHDC1,CDON,KLHL5,KMT5B,SCML2,HSP90AA1,ZNF678,KCNN3,MKLN1,AFF1,OLR1,HSPA4L,TCEA1,DOCK9,RGMB,TRPS1,SLC38A1,JMJD1C" MicroRNA hsa-miR-4688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.93E-11 3.89E-07 1.09E-10 1.00E-09 25 105 "GPRIN1,ELFN2,SYT13,OGT,PHF12,ARHGDIA,ATP1B3,CAMK2A,NOS1AP,SPATA2,AHDC1,CRCP,POLL,B4GALNT4,MDM4,HS6ST3,PKD1,MTRF1L,TMCC1,NSD1,TMPRSS5,TUBB2A,RPL7L1,URM1,WIPF2" MicroRNA hsa-miR-511-5p:Functional MTI Functional MTI miRTarbase 6.93E-11 3.89E-07 1.09E-10 1.00E-09 25 105 "TTYH1,TNRC6C,CA8,BAG4,PITPNM3,DPP6,FEM1B,FRY,ELAVL3,SRRM4,KAT7,RASSF8,KIAA1755,KCNN3,CD200,SESN3,KSR2,GLIPR1L2,PGBD4,NAXD,KIF1B,SRPK2,PCDHA6,ZNF711,PMEPA1" MicroRNA hsa-miR-3197:mirSVR_highEffct hsa-miR-3197:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.95E-11 3.91E-07 1.09E-10 1.00E-09 30 148 "FAM135A,NUMB,ADGRB2,CBLN1,CLCN3,FAM19A5,CNTNAP2,DGKG,SGSM2,SIDT2,DUSP27,STRADA,PSD2,FAM120B,CYP46A1,SLC35G1,MAN2A2,SYT9,GDAP1L1,ZSCAN2,KCTD17,RNF220,LINC00461,SMARCD3,DBNDD2,HIF3A,AMACR,TRIM9,WNK3,NLRP3" MicroRNA hsa-miR-6728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.97E-11 3.92E-07 1.09E-10 1.01E-09 24 97 "TBPL1,PITPNM3,KIAA0408,C2CD2L,SV2B,EDN3,ELAVL3,FKTN,FGF1,UFM1,RFFL,GRIK3,GSN,NKD1,NCOA7,PAX6,PLCL1,PKIA,UEVLD,SNAP25,GPRIN3,TSC1,UBE2H,UPF3A" MicroRNA hsa-miR-6848-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-11 3.96E-07 1.10E-10 1.02E-09 38 225 "TMEM132B,NLGN4X,ATP1B3,MTMR3,STOML1,MYADM,FGFR1OP2,BLOC1S6,SV2B,RABGAP1L,NR1D2,MTSS1L,MRPL37,RCSD1,ZNF585B,CELF1,FAXC,GRID1,DDX19B,ATCAY,MAN2A2,MYO5A,MYO6,NUCB1,PCSK2,SKOR1,ZSCAN2,ZMAT4,DCUN1D2,KLHDC8A,SGSM1,FAM126B,KIF1B,ERBIN,ZNF34,TPM3,SGK3,MSRB3" MicroRNA hsa-miR-6843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.04E-11 3.96E-07 1.10E-10 1.02E-09 38 225 "TMEM132B,NLGN4X,ATP1B3,MTMR3,STOML1,MYADM,FGFR1OP2,BLOC1S6,SV2B,RABGAP1L,NR1D2,MTSS1L,MRPL37,RCSD1,ZNF585B,CELF1,FAXC,GRID1,DDX19B,ATCAY,MAN2A2,MYO5A,MYO6,NUCB1,PCSK2,SKOR1,ZSCAN2,ZMAT4,DCUN1D2,KLHDC8A,SGSM1,FAM126B,KIF1B,ERBIN,ZNF34,TPM3,SGK3,MSRB3" MicroRNA hsa-miR-4797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.12E-11 4.00E-07 1.11E-10 1.03E-09 37 215 "ABCF1,NLGN4X,SLC24A4,HACE1,KIAA1324,TBRG4,COL9A2,RTTN,DBT,DNAH9,DNAJB6,E2F6,TMEM35A,ZNF549,ZNF234,SRCAP,KAT7,DDX19B,ZDHHC15,DOCK7,SCIN,IBA57,KCNN3,MBD1,MOG,NFIX,OLR1,MTMR10,STK32A,RDX,SATB1,IL17RB,EMC1,TROVE2,AGTPBP1,SLC44A1,PPIL6" MicroRNA hsa-miR-944:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.44E-11 4.18E-07 1.16E-10 1.07E-09 27 122 "FMNL2,SLC24A4,GPR158,HECW2,APP,ATP2A2,BACH1,FOXK1,CDC27,SRSF11,DPYSL2,DNAJB6,KIAA1109,GATM,SNRK,SPDL1,SETD5,CHD9,BTBD3,LIMCH1,BDP1,ZMAT3,TLL2,UBE3A,WNK1,EVI5,FXR1" MicroRNA hsa-miR-1298-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.60E-11 4.27E-07 1.19E-10 1.09E-09 18 54 "AK2,KIAA1614,EDN1,KLHL5,EN2,ACSL4,TMEM107,GPR45,SYNPO,SHISA6,PALLD,TCF7L2,NR2E1,TSC1,ZNF70,SIGLEC10,NAV2,FXR1" MicroRNA hsa-miR-4672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.00E-11 4.49E-07 1.25E-10 1.15E-09 28 131 "ESYT2,CD81,SLC24A2,BAG4,CREB5,PITPNC1,SORBS3,WAC,TESK2,SYT17,DIDO1,NR3C1,ZIC5,ZNF678,KIF5C,SFXN5,SESN3,NEXMIF,NAP1L1,PPP2R5E,PKN2,CNNM2,ZNF532,C12orf49,ZNF415,NR2C2,UBTF,DHX33" MicroRNA hsa-miR-2276-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.08E-11 4.54E-07 1.26E-10 1.16E-09 31 158 "XKR4,SPOP,CDC14B,ARSE,DLGAP3,RNF14,MATR3,HEYL,MRO,TUBD1,SLC43A2,MED12L,MSANTD4,MYOZ2,CRCP,SCRG1,LIMS1,MAPT,PDGFRA,STRN3,APTX,PTAFR,ZSCAN2,UEVLD,BCAN,DIP2A,WWC1,ACSL6,TPCN2,ARL10,ERCC6L2" MicroRNA hsa-miR-652:mirSVR_highEffct hsa-miR-652:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.51E-11 4.78E-07 1.33E-10 1.22E-09 23 90 "KLHL32,ALCAM,TRIM41,LGI1,AKAP6,PDE4DIP,NRSN1,TOX,DTNA,KRBA2,PHC2,SRRM1,NPTN,TNRC6A,GNAO1,ITGA7,KCNB1,KCNK2,FOXRED1,UNC80,SS18,MPPE1,DNAH10" MicroRNA hsa-miR-548ay-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-11 4.78E-07 1.33E-10 1.22E-09 23 90 "XKR4,SLC24A4,TNRC6C,FOXK1,FMNL3,ZNF385A,TOMM20,E2F6,AFF2,NCKAP1,MIER3,IL6R,ITPKB,MAT2A,SAMD5,CTNNA3,STRN3,ROBO1,LRRC55,SON,AJAP1,FAM208A,CADM2" MicroRNA hsa-miR-548at-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.51E-11 4.78E-07 1.33E-10 1.22E-09 23 90 "XKR4,SLC24A4,TNRC6C,FOXK1,FMNL3,ZNF385A,TOMM20,E2F6,AFF2,NCKAP1,MIER3,IL6R,ITPKB,MAT2A,SAMD5,CTNNA3,STRN3,ROBO1,LRRC55,SON,AJAP1,FAM208A,CADM2" MicroRNA hsa-miR-132*:mirSVR_highEffct hsa-miR-132*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 8.64E-11 4.85E-07 1.35E-10 1.24E-09 25 106 "SYS1,FAM131A,CAST,DGKI,SRSF11,SRP14-AS1,DPH1,YAF2,GOLGA7,FAM198B,MALT1,GNAO1,GPD2,NF1,PCDH9,PCSK5,POLR2F,KANSL3,SNAP25,TPCN2,WDR7,PMS2CL,PIK3R5,TRPS1,ADAMTSL3" MicroRNA hsa-miR-3591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.79E-11 4.94E-07 1.37E-10 1.26E-09 24 98 "USP37,CDC14B,CLCN3,CSNK1G3,ZC3H11A,CPEB2,DNAJB6,FARSB,GOLT1B,MSANTD4,FREM1,RAB30,MBNL1,PURG,ROBO1,UEVLD,TRA2B,SLC6A8,ZNF621,TROVE2,ZMAT3,NSD2,ZXDA,WIPF2" MicroRNA hsa-miR-4646-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.99E-11 5.05E-07 1.40E-10 1.29E-09 20 68 "SLC12A5,MTUS1,CA12,CHD5,PITPNM3,UBXN2A,CELSR3,CELF1,NR3C1,METTL21A,KCNJ10,SHC3,ZDHHC22,SEPT4,RDX,CSRNP3,GALNT10,SHANK2,NR2E1,VLDLR" MicroRNA hsa-miR-1226-3p:Functional MTI Functional MTI miRTarbase 9.20E-11 5.17E-07 1.44E-10 1.32E-09 38 227 "RBM10,NDRG3,ADAR,ATP2A2,PLXNA4,LONRF1,TM9SF4,ELMO1,SACS,EPB41L1,ERCC2,TBC1D16,TUBB4A,DLC1,RACK1,FGFR1,GPR26,GRIK3,TMEM25,FAM107A,HSP90AA1,SHISAL1,LIMS1,NDUFA5,NDUFS7,ZDHHC4,PBRM1,CNTNAP3,ATXN2,TRIM67,ZNF106,CABIN1,USP1,ZNF781,ZNF154,ZNF195,CSDE1,ZNF248" MicroRNA hsa-miR-7157-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.55E-11 5.37E-07 1.49E-10 1.37E-09 31 159 "FMNL2,SLC24A4,KIF6,ZNF582,MTMR3,ISPD,PLXNA4,RIMS3,MAML1,YTHDC1,DMPK,FEM1B,SH3GLB1,GPR61,PLEKHA1,SCML2,CELF1,CAB39,ZNF680,GTDC1,SALL1,ZKSCAN3,PEG10,TGFBR3,KCTD2,RFTN2,AMOT,MGAT5B,WRN,DHX33,SPATA13" MicroRNA hsa-miR-4310:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.55E-11 5.37E-07 1.49E-10 1.37E-09 31 159 "FMNL2,SLC24A4,KIF6,ZNF582,MTMR3,ISPD,PLXNA4,RIMS3,MAML1,YTHDC1,DMPK,FEM1B,SH3GLB1,GPR61,PLEKHA1,SCML2,CELF1,CAB39,ZNF680,GTDC1,SALL1,ZKSCAN3,PEG10,TGFBR3,KCTD2,RFTN2,AMOT,MGAT5B,WRN,DHX33,SPATA13" MicroRNA hsa-miR-196b-5p:Functional MTI Functional MTI miRTarbase 9.86E-11 5.54E-07 1.54E-10 1.42E-09 30 150 "BRAP,MTUS1,BCAR3,FAM135A,IGDCC4,BACH1,CDK5R1,CALM1,FMNL3,LHX2,DCTN4,RACK1,SARAF,SALL3,PRUNE2,SLC35G1,PAXBP1,MAT2A,MEIS1,NAP1L1,PBX1,BEST3,PPARA,RDX,SLC6A15,ARMH4,KIF27,HSPA4L,TGFBR3,TRPC3" MicroRNA hsa-miR-6777-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-10 5.63E-07 1.56E-10 1.44E-09 22 83 "GPRIN1,CASKIN1,LTBP4,PDZD4,CLU,TMEM184B,ZNF385A,SEC16A,TBR1,NKX6-2,WASF3,HMX1,SHISA6,PABPC1L2A,SLC11A2,PLIN1,EPN1,TNPO2,EMID1,CLIP1,SBF1,MAPK8IP3" MicroRNA hsa-miR-6889-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-10 5.63E-07 1.56E-10 1.44E-09 22 83 "GPRIN1,CASKIN1,LTBP4,PDZD4,CLU,TMEM184B,ZNF385A,SEC16A,TBR1,NKX6-2,WASF3,HMX1,SHISA6,PABPC1L2A,SLC11A2,PLIN1,EPN1,TNPO2,EMID1,CLIP1,SBF1,MAPK8IP3" MicroRNA hsa-miR-6854-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-10 5.63E-07 1.56E-10 1.44E-09 22 83 "CDR1,SEC24C,PPP1R16B,KLHL3,CAMKK2,PCDH17,C5orf24,NKD1,SLC35G1,CYP27C1,GPSM2,PLEC,FITM2,PTGR2,NCBP3,RMI1,KIF21B,KLHL7,CAMSAP2,RBFOX2,PRDM2,CSDE1" MicroRNA hsa-miR-143-3p:Functional MTI Functional MTI miRTarbase 1.05E-10 5.90E-07 1.64E-10 1.51E-09 38 228 "ABAT,SLC25A25,MTA3,OSBPL8,CDC25B,BTF3L4,CTNND1,DBT,JAKMIP2,DTNB,PLEKHA1,C1orf61,NCKAP1,FAXC,GLUL,PRRC2B,KAT7,MIER3,KCNJ3,CREG2,MYO6,NOS1,NUCB1,PDGFRA,PIK3R1,ZNF426,PPP2R5E,MAPK7,ELP2,SCN2B,ELMOD1,FAM102A,NUBPL,KIAA0930,NR2C2,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-620:Functional MTI Functional MTI miRTarbase 1.07E-10 6.03E-07 1.67E-10 1.54E-09 25 107 "TEX22,SLC24A4,PDE4DIP,UBXN2A,TMEM170A,SPATA2,DYRK1A,FARSB,ABI2,TUBD1,FAM184B,PRRC2B,CNDP1,BACH2,SHISA6,KLHL23,C10orf105,NEUROD1,OLA1,FAT3,RAB5B,AHCYL2,SIK3,TUBB2A,ITM2C" MicroRNA hsa-miR-3607-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-10 6.21E-07 1.72E-10 1.58E-09 24 99 "ABCD2,MARCH4,ARNTL,STX16,NIPA1,FOXN3,NRXN1,QKI,BTF3L4,FAM107B,EIF4G2,ELAVL2,PLEKHA1,SCML2,CELF1,GRIK4,MIER3,OPHN1,PBRM1,CHD9,CPEB4,CLSTN2,EVI5,ZDHHC20" MicroRNA hsa-miR-579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-10 6.33E-07 1.75E-10 1.61E-09 31 160 "BRAP,KIAA1211,APP,CDK13,CALM1,APPL1,TENM1,EN2,EPHB1,CAMKK2,FUT9,KIAA1841,GPR26,ADAMTS8,INSYN1,MAGEL2,PKIA,MDGA2,ACSS3,RNASEL,SETD5,TMLHE,CCDC25,FBXW7,ACER3,ZNF331,TRAPPC13,TROVE2,PRDM10,NAV2,TMEM63C" MicroRNA hsa-miR-4472:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-10 6.43E-07 1.78E-10 1.64E-09 33 179 "TRMT9B,AMPD3,BCL7A,CAMK2A,CBARP,DLGAP3,TMEM184B,ZNF385A,PYGO1,PLEKHM1,EFNA3,MRNIP,ELN,ANKRD13B,DOT1L,MTHFD2,GFER,PRRC2B,TJAP1,MAP4,PKM,NLE1,PLEC,SMOX,SLC25A23,SDK2,SPATA6,ATXN2,SMTN,PKNOX2,PEG10,NACC2,RICTOR" MicroRNA hsa-miR-4447:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-10 6.43E-07 1.78E-10 1.64E-09 33 179 "TRMT9B,AMPD3,BCL7A,CAMK2A,CBARP,DLGAP3,TMEM184B,ZNF385A,PYGO1,PLEKHM1,EFNA3,MRNIP,ELN,ANKRD13B,DOT1L,MTHFD2,GFER,PRRC2B,TJAP1,MAP4,PKM,NLE1,PLEC,SMOX,SLC25A23,SDK2,SPATA6,ATXN2,SMTN,PKNOX2,PEG10,NACC2,RICTOR" MicroRNA hsa-miR-4632-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-10 6.54E-07 1.81E-10 1.67E-09 28 133 "XKR4,ATP1B3,BSN,NUMBL,TM9SF4,CTIF,DNM2,SH3GLB1,AMOTL2,SRCAP,GJB1,KCNH1,PPM1L,NEUROD2,PACSIN1,C1orf109,SH3TC2,ZMAT4,SLC6A9,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,TMPRSS5,PMEPA1,GAN" MicroRNA hsa-miR-4646-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-10 6.54E-07 1.81E-10 1.67E-09 28 133 "MYOM2,COL9A2,RGS6,ASB3,VPS26C,AMOTL2,MTHFD2,CRCP,GLUL,POLL,LILRA2,BVES,NEGR1,ATCAY,KCNK1,KCTD15,KIAA0895L,PEX26,UNC5B,NFASC,NXT2,AJAP1,FGD4,HIF3A,CBX5,BHLHB9,ZBTB38,XKR7" MicroRNA hsa-miR-7843-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-10 6.54E-07 1.81E-10 1.67E-09 28 133 "XKR4,ATP1B3,BSN,NUMBL,TM9SF4,CTIF,DNM2,SH3GLB1,AMOTL2,SRCAP,GJB1,KCNH1,PPM1L,NEUROD2,PACSIN1,C1orf109,SH3TC2,ZMAT4,SLC6A9,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,TMPRSS5,PMEPA1,GAN" MicroRNA "CCAGGTT,MIR-490:MSigDB" "CCAGGTT,MIR-490:MSigDB" MSigDB 1.20E-10 6.71E-07 1.86E-10 1.71E-09 19 62 "OGT,ARHGAP33,AHCTF1,GGT7,SCRT2,MSI1,MDGA2,OXR1,GTDC1,PBRM1,SCN4B,SLC1A3,FAM219A,SOX11,CAMTA1,SZT2,NR2C2,SLC35A4,GAL3ST3" MicroRNA hsa-miR-296-5p:PITA hsa-miR-296-5p:PITA_TOP PITA 1.21E-10 6.77E-07 1.87E-10 1.72E-09 20 69 "UNC5A,LRFN1,PPFIA3,CCAR2,GPC2,CNTFR,CLIP3,CTIF,SMG7,MED12,DMTN,TAOK3,AHDC1,RNF165,NEUROD2,CYB561D1,SOX11,SLC30A3,PCBP4,ADAMTS10" MicroRNA hsa-miR-4790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-10 7.27E-07 2.01E-10 1.85E-09 22 84 "XKR4,AKAP5,SLC35F1,SV2B,ERBB2,ZNF585B,ATP13A4,STAMBP,GABRB1,NXPH2,PPM1L,NCAM2,SMIM7,PSAT1,SARS,DRAXIN,SLC2A5,MBD5,SPART,FAM208A,VSNL1,C12orf4" MicroRNA hsa-miR-6758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-10 7.47E-07 2.06E-10 1.90E-09 25 108 "ADCYAP1R1,NLGN4X,MTA3,KIAA1614,FOXK1,MAP7,CLTC,LETMD1,FEM1B,ANKMY1,CACNG2,GABRA1,GCK,PARD3B,UBE2QL1,IBA57,MDM4,PAK3,CAMKV,SMIM7,POU6F1,RDX,SETD5,PEG10,TPM3" MicroRNA hsa-miR-4281:mirSVR_highEffct hsa-miR-4281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.38E-10 7.77E-07 2.15E-10 1.98E-09 24 100 "PKP4,PHF19,SLC29A4,ABCC9,FCF1,NELFCD,AP4B1,HBS1L,TNRC6A,GPD2,ADAMTS13,BEST3,HERC2P3,ZFYVE21,RETREG2,MASP1,SIDT1,RFX4,SCN8A,PAAF1,HECW1,MYCBP2,SEPT8,PRMT8" MicroRNA hsa-miR-4468:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-10 7.80E-07 2.15E-10 1.98E-09 30 152 "XKR4,AK2,DOCK11,ST3GAL5,FMNL3,LRWD1,PLAA,UBXN2A,G3BP2,DNAH9,E2F6,FCF1,EFNA3,ZNF585B,CAMSAP1,MSANTD4,ATP8A2,CRCP,TNRC6A,PRRC2B,RBPJ,IBA57,LRRC4B,OGDH,PLEKHB2,ATXN1,ZNF106,WBP2,DHX33,GAN" MicroRNA hsa-miR-761:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-10 7.80E-07 2.15E-10 1.98E-09 30 152 "ELFN2,CASKIN1,SFMBT2,PDXK,ZBTB10,LDLRAD4,TBPL1,CS,NCAN,SOCS5,RUBCN,HEYL,FGFR1,FAM49B,NPTN,DKK3,MTHFD2,GNAL,PPM1L,KCTD15,CNNM2,SCN4B,CPEB4,ERC1,TPM3,LRTM2,RPL7L1,BCL2L13,VAV2,GDPD5" MicroRNA hsa-miR-6738-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-10 7.87E-07 2.17E-10 2.00E-09 28 134 "PNMA8B,ARRB2,ASPH,MTMR3,FOXK1,ARHGEF2,EVI5L,NOS1AP,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,DMTN,SEPT9,RNF165,MMP17,NFIX,OGDH,OLR1,HSD11B1L,SLC2A5,RAP1GAP2,TAB2,CAMTA2,SEPT8,AJAP1,RPL7L1" MicroRNA hsa-miR-3160-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-10 8.32E-07 2.29E-10 2.11E-09 21 77 "ATP1A1,ATP1A2,SH2B1,EMX2,CDHR1,AMOTL2,SRRM4,RFFL,HMGCR,MAT2A,CCSER2,SNX10,FNDC3A,ZFP1,MPRIP,NACC2,RGMB,NEIL2,RICTOR,WNK2,ZDHHC20" MicroRNA hsa-miR-4286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-10 8.46E-07 2.33E-10 2.15E-09 26 117 "TAOK1,ATP1A3,KSR1,CASTOR3,CACNA1E,DIRAS1,RIMS3,IP6K1,SIRPA,EPB41L1,SEMA4D,ATP13A4,ANKFY1,NSG2,ST6GALNAC3,SLC6A17,XRRA1,NFYA,SEC61A2,CLIP1,SLC37A2,TBX15,TMEM151B,NSD1,RIMBP2,ZNF781" MicroRNA hsa-miR-1185-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-10 8.46E-07 2.33E-10 2.15E-09 26 117 "ZNF608,VAT1L,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,BRPF3,EML4,GRIK3,NCOA7,MBNL1,SESN3,KCNK10,PCSK1,PFKFB2,TMEM104,KIF13A,DIP2A,GPRIN3,FBXL16,TMOD1,USP1,WNK1" MicroRNA "TCCCCAC,MIR-491:MSigDB" "TCCCCAC,MIR-491:MSigDB" MSigDB 1.51E-10 8.48E-07 2.34E-10 2.15E-09 18 56 "SEMA4G,DNAJB5,PUM1,C2CD2L,PLPPR4,DMPK,APH1A,GPD1,IL1RAPL1,KAT7,ATXN2L,ITPKA,MEIS2,MN1,PDGFRA,MAPKAP1,SEMA6D,TCF7" MicroRNA hsa-miR-664b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-10 8.78E-07 2.42E-10 2.23E-09 31 162 "BRAP,KIAA1211,APP,CDK13,CALM1,APPL1,TENM1,EN2,EPHB1,CAMKK2,FUT9,KIAA1841,GPR26,ADAMTS8,INSYN1,MAGEL2,PKIA,MDGA2,ACSS3,RNASEL,SETD5,TMLHE,CCDC25,FBXW7,ACER3,ZNF331,TRAPPC13,TROVE2,PRDM10,NAV2,TMEM63C" MicroRNA hsa-miR-639:mirSVR_highEffct hsa-miR-639:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-10 8.78E-07 2.42E-10 2.23E-09 31 162 "TKTL1,NLGN4X,LRFN1,SEMA7A,BCL7A,DDR1,CDC42,RTTN,MICAL2,CNIH3,BLOC1S6,ZNF585B,TBR1,ZNF276,GRIA4,ZBTB49,HNRNPK,MAP4,DNHD1,ODF2,CRLS1,KANSL1,TMEM260,ZNF532,ATXN7,NUBPL,SMARCE1,WDTC1,SOX3,TAB2,ZEB1" MicroRNA hsa-miR-3191:mirSVR_highEffct hsa-miR-3191:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.62E-10 9.12E-07 2.51E-10 2.31E-09 27 126 "VWA5B2,ABR,SLC12A5,PCDH10,TTLL9,CNIH3,E2F5,EPB41L1,TBC1D16,BRSK1,B4GALNT1,LRRC37A6P,LOXL3,PRDM5,KCNJ3,MAN2A2,GPR137C,PLP1,PROX1,KIF16B,SMARCD3,ADHFE1,TRPM2,FAM155A,SPHK2,CELF4,SLC17A7" MicroRNA hsa-miR-5695:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-10 9.12E-07 2.51E-10 2.31E-09 27 126 "ATP1B3,CACNA1A,SLC24A2,FGFR1OP2,FRMPD4,SEC16A,TMTC1,CELSR3,F3,CAB39,PTGDR2,BACH2,KNDC1,IL6R,KCNB1,MYO5A,NPTX1,CDK18,PDE1A,CYB561D1,PCMTD2,ATXN7,NFASC,NSD1,SLC44A1,SGK3,ZNF248" MicroRNA hsa-miR-6891-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-10 9.34E-07 2.57E-10 2.37E-09 22 85 "C3orf14,CFAP410,CLTC,IGDCC3,ERBB2,MRPL37,GCK,PCDH17,HMGB1,KCNN1,CTNNA3,HMGCLL1,TNPO2,NCR3LG1,PEX2,STX1B,TMEM178B,TNFRSF1B,VLDLR,DHX33,URM1,GAN" MicroRNA hsa-miR-6735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-10 9.45E-07 2.60E-10 2.39E-09 28 135 "XKR4,ATP1B3,BSN,NUMBL,TM9SF4,CTIF,DNM2,SH3GLB1,AMOTL2,SRCAP,GJB1,KCNH1,PPM1L,NEUROD2,PACSIN1,C1orf109,SH3TC2,ZMAT4,SLC6A9,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,TMPRSS5,PMEPA1,GAN" MicroRNA hsa-miR-5194:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-10 9.45E-07 2.60E-10 2.39E-09 28 135 "PNMA8B,ARRB2,ASPH,MTMR3,FOXK1,ARHGEF2,EVI5L,NOS1AP,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,DMTN,SEPT9,RNF165,MMP17,NFIX,OGDH,OLR1,HSD11B1L,SLC2A5,RAP1GAP2,TAB2,CAMTA2,SEPT8,AJAP1,RPL7L1" MicroRNA hsa-miR-548l:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-10 9.57E-07 2.63E-10 2.42E-09 32 172 "SORCS2,BACH1,FOXK1,CPS1,RAB39B,ELAVL2,KATNAL1,SGIP1,MTHFD2,GPR26,KIF3A,HSP90AA1,IL6ST,ZNF678,KLRC3,CHST6,MKLN1,PPP2R5E,REV3L,ALG9,ZNF354C,ATF7IP,KIF1B,ZBTB43,ATMIN,PCDHA6,ARL10,NACC2,RBFOX2,UBE2H,ZNF711,PAK5" MicroRNA hsa-miR-6818-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-10 9.57E-07 2.63E-10 2.42E-09 32 172 "SPAG9,FMNL3,SOCS6,BAG4,USP6NL,TMEM170A,C2CD2L,HEYL,UFM1,NCKAP1,SYTL4,LSAMP,PALM,PDE3A,SMIM7,PIGG,CNTLN,BSDC1,NCBP3,TRA2B,FAM214B,MCF2L2,DIP2A,FAM208A,SZT2,HHIP,TPM3,VLDLR,ZNF708,LMAN2L,NAV2,PLSCR4" MicroRNA hsa-miR-655-3p:Functional MTI Functional MTI miRTarbase 1.73E-10 9.71E-07 2.67E-10 2.46E-09 24 101 "CAPRIN2,NRP2,CANX,MAGI2,HIPK3,TMTC1,GPR26,DIPK1A,MID1,SESN3,PRRX1,SATB1,TRIM67,TROVE2,EXOC7,CAMSAP2,ZEB1,TRIM2,PSD3,TRPS1,ZNF610,TBC1D15,SPIRE1,ZDHHC20" MicroRNA hsa-let-7c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-10 9.71E-07 2.67E-10 2.46E-09 24 101 "USP28,DDX3Y,JAZF1,CALM1,MAP7,NIPBL,BAG4,DNAJB6,STARD3NL,WAC,TACC2,IL6R,MMP16,OLR1,PKN2,PSD,FIGN,SEC14L1,TRA2B,FAM126B,NECAB1,PRRC2C,SLC44A1,CSMD1" MicroRNA hsa-miR-602:PITA hsa-miR-602:PITA_TOP PITA 1.81E-10 1.02E-06 2.79E-10 2.57E-09 15 38 "ARID1A,ZBTB10,SYT6,KIAA1549L,TENM4,DPP6,RASGRP2,WAC,TAOK3,FOXG1,CHL1,MID1,NELL1,NRCAM,GPR85" MicroRNA hsa-miR-517c:PITA hsa-miR-517c:PITA_TOP PITA 1.92E-10 1.08E-06 2.95E-10 2.72E-09 16 44 "SLITRK1,EIF4G3,BSN,CACNA1A,ZNF521,DBN1,LYPD1,SMG7,PTK2B,LRRTM3,OLFM3,ZYG11B,TMCC1,USP1,MPPE1,CBLN2" MicroRNA hsa-miR-517a:PITA hsa-miR-517a:PITA_TOP PITA 1.92E-10 1.08E-06 2.95E-10 2.72E-09 16 44 "SLITRK1,EIF4G3,BSN,CACNA1A,ZNF521,DBN1,LYPD1,SMG7,PTK2B,LRRTM3,OLFM3,ZYG11B,TMCC1,USP1,MPPE1,CBLN2" MicroRNA hsa-miR-7108-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-10 1.08E-06 2.97E-10 2.74E-09 21 78 "MARCH4,LRFN1,MARK4,LDHD,FOXK1,CBARP,TOGARAM2,ZNF385A,NCOR2,PITPNM3,EPB41L1,NCKAP1,KIAA1958,KIFC3,XRRA1,MSR1,AJAP1,SZT2,NAT16,DAAM2,SSBP2" MicroRNA hsa-miR-212-3p:Functional MTI Functional MTI miRTarbase 2.20E-10 1.23E-06 3.38E-10 3.11E-09 23 94 "DPF1,ACHE,TNRC6C,ABCG2,UBXN2A,CALN1,PHF20L1,IRAK4,ACSL4,EML4,TJAP1,LIFR,PTCH1,RAB5B,SH3TC2,SETD5,SOX11,CRTC1,TJP1,SGK3,ZNF711,PARP11,FXR1" MicroRNA hsa-miR-3616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-10 1.26E-06 3.45E-10 3.18E-09 26 119 "ADARB2,DYNLL1,CANX,CLCN3,C3orf18,DMTN,FKTN,FICD,MARK1,SYT9,MTR,MYO5A,GPR137C,SLC25A23,PKN2,PLEKHB2,FNDC3A,ANKRD6,CPEB4,DDN,CAMSAP2,TBCEL,ZNF106,KAT6B,ZKSCAN5,PITPNB" MicroRNA hsa-miR-4436b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-10 1.36E-06 3.72E-10 3.42E-09 28 137 "XKR4,ATP1B3,BSN,NUMBL,TM9SF4,CTIF,DNM2,SH3GLB1,AMOTL2,SRCAP,GJB1,KCNH1,PPM1L,NEUROD2,PACSIN1,C1orf109,SH3TC2,ZMAT4,SLC6A9,SSTR1,PUM2,NACC2,CBX5,RGMB,SMUG1,TMPRSS5,PMEPA1,GAN" MicroRNA hsa-miR-370-3p:Functional MTI Functional MTI miRTarbase 2.49E-10 1.40E-06 3.82E-10 3.52E-09 25 111 "SFMBT2,SEMA4G,GPR146,DST,CACNA1A,CANX,CDC27,RAB3C,BAG4,WDPCP,IRAK4,FOXM1,AFF2,SRCAP,KIAA1958,KCNN1,NF1,KCTD15,HMGCLL1,SPATA6,CYB561D1,SCN7A,PEAR1,NFASC,DHX33" MicroRNA hsa-miR-382-5p:Functional MTI Functional MTI miRTarbase 2.49E-10 1.40E-06 3.82E-10 3.52E-09 25 111 "SYT13,SYNJ2,CALM1,CLTC,RBM39,KLHL3,G3BP2,DRD1,YAF2,COPS4,PNMA2,MTHFD2,KIF5C,NEXMIF,NFIA,PFKFB2,ATXN1,FNIP1,SLC6A8,MTCL1,DICER1,ZKSCAN5,XPO1,PLSCR4,NETO2" MicroRNA hsa-miR-1251-5p:TargetScan hsa-miR-1251-5p TargetScan 2.50E-10 1.41E-06 3.85E-10 3.55E-09 21 79 "BRAP,GRAMD1B,ANK1,APBB2,FMNL3,ERBB4,MTHFD2,RNF165,CELF3,HLF,IGF1,KIF5A,MMP16,NOVA2,PKIA,PROX1,GTDC1,FIGN,CBX5,AMOT,NETO1" MicroRNA hsa-miR-6513-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-10 1.42E-06 3.89E-10 3.58E-09 31 165 "AS3MT,TPP1,ENTPD4,ANKRD44,PDE4DIP,MYADM,ZBTB24,RABGAP1L,PLEKHO1,WAC,FKTN,ATP13A4,APOPT1,SRCAP,KIF3A,HAS2,EID2B,STMN1,MAN2A2,CHST6,ZNF426,NWD1,GSTCD,PGBD4,ANKRD36,CLUAP1,ZC3H4,AGTPBP1,ZMAT3,ZNF34,SSBP2" MicroRNA hsa-miR-676-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-10 1.43E-06 3.91E-10 3.61E-09 17 51 "SERPINA3,RNF157,ATP2B3,UBXN2A,CCDC144A,E2F6,GABRB1,IL6ST,KCNJ10,SEPT4,RPL15,ARMH4,ZMAT3,RPL7L1,VLDLR,ZNF24,MVB12B" MicroRNA "CCCACAT,MIR-299-3P:MSigDB" "CCCACAT,MIR-299-3P:MSigDB" MSigDB 2.55E-10 1.43E-06 3.91E-10 3.61E-09 17 51 "ADD1,RUNX1T1,CDC42,TMEM35A,RABEPK,AGBL5,ITGAV,KCNMA1,GIT1,SP4,IQSEC2,PDLIM2,TCF4,UBE2H,PLEKHH2,PARP6,XKR7" MicroRNA hsa-miR-139-3p:mirSVR_highEffct hsa-miR-139-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-10 1.50E-06 4.10E-10 3.78E-09 24 103 "MARCH4,PRC1,NIPBL,PPP6R2,IP6K1,EGFR,OLFM1,SMC2,INPP5K,GJB1,NDP,SMIM11A,OGG1,CDK14,DUSP26,PLP1,FUZ,CAMTA2,TRIM2,TMOD1,ELP5,RUSC1,RPL7L1,URM1" MicroRNA hsa-miR-583:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-10 1.52E-06 4.15E-10 3.82E-09 30 156 "SDE2,ARID1A,CC2D2A,ZNF578,APP,CCAR2,CALM1,AKAP6,ENTPD4,DBN1,PLEKHM1,CHRDL1,TRAPPC9,WAC,SARAF,FAXC,PTPRT,NKD1,KITLG,GPR137C,PDZRN4,TNPO2,KIF27,CCDC88A,SON,SPART,TAB2,DIP2A,PUM2,CBX5" MicroRNA hsa-miR-4778-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-10 1.52E-06 4.15E-10 3.82E-09 32 175 "RALGAPA1,FMNL2,SPOP,CACHD1,ASCL1,ATP1A2,VXN,NUMBL,SOCS5,PLCXD3,RABGAP1L,ST8SIA3,ABI2,TENM1,RABEPK,DLC1,TMEM151A,GABRB1,GABRG2,FAXC,GRIK3,HMGB1,SHISA6,SRSF12,NODAL,NPTX2,PLCL1,POLG,PRKCB,AP1AR,BDP1,MAPK8IP3" MicroRNA hsa-miR-4494:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-10 1.55E-06 4.23E-10 3.90E-09 23 95 "ARNTL,DOCK11,COL9A2,C2CD2,KIAA0586,ZC3H11A,EN2,VPS13B,PTPRT,RNFT2,SHISA6,KCTD6,PTPA,PTAFR,ATP8B4,RTKN,FNDC3A,AGTPBP1,PUM2,KCTD2,VSNL1,TFIP11,MPPE1" MicroRNA hsa-miR-6073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.76E-10 1.55E-06 4.23E-10 3.90E-09 23 95 "PHF12,APP,ARNTL,ASPH,FOXN3,CLTA,HECTD1,ACBD5,IP6K1,MTX3,DCTN4,MALT1,GNAS,IL6ST,ZNF678,KIF5A,TTYH2,AFF1,RDX,KIF27,PEX26,TAB2,ZNF24" MicroRNA "CTCAAGA,MIR-526B:MSigDB" "CTCAAGA,MIR-526B:MSigDB" MSigDB 2.81E-10 1.58E-06 4.31E-10 3.97E-09 20 72 "MTUS1,HECW2,OGT,ARRB1,CAPN3,CPEB2,FGF1,DNER,PCDH17,ICA1,MKLN1,ZNF827,CCSER2,STRN3,RGS12,ZFHX4,ROBO1,ARX,HHIP,ZFP91" MicroRNA hsa-miR-3154:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-10 1.59E-06 4.34E-10 3.99E-09 29 147 "MTUS1,TRMT9B,OGT,DCAF5,TMEM184B,CTNND1,ZC3H11A,ING4,CRCP,POLL,MIER3,IDH3A,MDM4,SCAMP5,MKLN1,SAMD14,PABPC1L2A,TMEM104,NWD1,PRRT2,ANKRD36,STX1A,USP22,ZNF34,ARL10,ZFP91,TPM2,MEAF6,URM1" MicroRNA hsa-miR-6079:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-10 1.60E-06 4.37E-10 4.03E-09 27 129 "OGT,ATP1B3,FMNL3,PREPL,CNTNAP2,EPB41,ZNF391,ZNF585B,FOXO3,TMEM151A,GCK,CYP46A1,CRCP,ZNF678,SGK1,R3HDM2,PEX26,ANKRD36,LIMCH1,SS18,TRIM2,HEY2,SMUG1,BCL2L13,ZNF708,FBXO36,SPATA13" MicroRNA hsa-miR-7154-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-10 1.63E-06 4.45E-10 4.10E-09 18 58 "BBS2,CA8,LONRF2,CPS1,EDIL3,EDN1,TENM1,PLEKHA1,MBNL1,MAPK8,SH3TC2,ATXN1,CHD9,NBPF1,ERBIN,KLHL4,RBFOX2,PRDM2" MicroRNA "GTTAAAG,MIR-302B:MSigDB" "GTTAAAG,MIR-302B:MSigDB" MSigDB 2.97E-10 1.67E-06 4.55E-10 4.20E-09 19 65 "ALCAM,ANK2,ARNTL,SYNJ1,NRXN3,CTNND2,CPEB2,ATP2C1,STAG2,GAD1,KCNMA1,PCDH9,PDGFRA,PRRX1,ING3,POU3F2,ROBO2,ATXN1,ST8SIA2" MicroRNA hsa-miR-3908:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.97E-10 1.67E-06 4.55E-10 4.20E-09 19 65 "TAOK1,APP,CASK,FOXK1,CPEB2,FAM13A,SESN1,C5orf24,IL6ST,METTL21A,FIGN,KCNIP3,HSPA4L,ACSBG1,CBX5,RGMB,ZBTB16,DHX33,GAN" MicroRNA hsa-miR-92a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-10 1.76E-06 4.79E-10 4.41E-09 39 247 "CPNE2,AP1B1,CASKIN1,ARRB1,BCL7A,DIRAS1,CAMK2A,DLGAP3,IP6K1,PLEKHM1,APH1A,MRNIP,ANKRD13B,DOT1L,MTHFD2,GFER,RNPS1,GLI2,PRRC2B,SHISA6,SOWAHA,KCNN3,NFIX,NKX2-2,TBC1D25,GPR173,PKM,NLE1,EPN1,SPATA6,FOXRED2,PEX26,PKNOX2,SLIT1,SPART,ARC,CLASP1,KCTD2,RICTOR" MicroRNA hsa-miR-671-5p:Functional MTI Functional MTI miRTarbase 3.18E-10 1.79E-06 4.87E-10 4.49E-09 30 157 "CPNE2,KIF6,OGT,ATP1B3,ATP2A2,FMNL3,CDR1,EPB41,ZNF391,RTN3,ZNF585B,FOXM1,FOXO3,USP21,TMEM151A,CYP46A1,ZNF678,MAOB,NACA,R3HDM2,PKNOX2,SSPO,SEPT3,SATB2,TRIM2,SMUG1,TSN,BCL2L13,FBXO36,SPATA13" MicroRNA hsa-miR-8076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-10 1.82E-06 4.95E-10 4.56E-09 21 80 "GRAMD1B,BACH1,RUNX1T1,CCNT1,CDC25B,DNAL1,G3BP2,MSANTD4,MPP6,BVES,HSF2,PTPRD,RAB5B,SATB1,ATXN1,TROVE2,MPRIP,ZC3H4,ARL10,ZFP91,SLC38A1" MicroRNA hsa-miR-519e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.26E-10 1.83E-06 4.99E-10 4.59E-09 33 186 "GPR158,TNRC6C,ATP1B3,CACNA1A,SLC24A2,BTF3L4,NRG2,FAM131B,FGFR1OP2,FRMPD4,NR1D2,CELF1,DKK3,CAB39,GPD1,RABL2A,PTGDR2,CELF5,IL6R,MYO5A,PDE1A,PRKAB2,CYB561D1,PCMTD2,ATXN1,ATXN7,SNAP25,ZNF621,GANAB,SGK3,ZNF138,WNK2,ZNF248" MicroRNA hsa-miR-3165:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-10 1.92E-06 5.24E-10 4.83E-09 27 130 "TAOK1,MYOM2,NRXN3,USP6NL,GAPVD1,RASSF2,TOMM20,SIRPA,DUSP9,DYRK1A,ABI2,ZNF549,MRPL10,MTHFD2,LUZP2,GNG4,PPM1L,MKLN1,PLXNB1,PACSIN1,TNPO2,RAB5B,CEP97,STUM,PEG10,SSBP2,EVI5" MicroRNA hsa-miR-6879-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-10 1.93E-06 5.25E-10 4.84E-09 28 139 "ADCY2,LRFN1,RTTN,DBT,OPTN,ABI2,TUBD1,COQ7,GPR75,GPR26,KAT7,MAP4,GPSM2,STRN3,PIGG,MTMR10,ZYG11B,PGBD4,HSPA4L,SLC22A4,ERC1,KLHL7,KIAA0930,ZNF34,ZNF106,ZNF781,ZNF74,TIGD6" MicroRNA hsa-miR-4262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-10 1.93E-06 5.25E-10 4.84E-09 28 139 "SLC25A25,HFM1,CAPRIN2,ATM,PNKD,DCAF4,FAM13A,EN2,EPS8,IQCG,ZDHHC15,NCOA7,PPP2R5E,ZNF844,ATXN7,SCN8A,CHD9,ZNF667,ZNF415,TMCC1,SPP1,UNC5B,SLC35G2,TUBB2A,ZNF781,NSD2,ZNF23,SPIRE1" MicroRNA hsa-miR-2115-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.44E-10 1.93E-06 5.26E-10 4.85E-09 22 88 "RALGAPA1,ZBTB10,BACH1,VXN,FCF1,ELN,JKAMP,MSANTD4,PCDH11X,HSF2,HSP90AA1,KCNJ3,AFF1,TCEAL5,PDE3A,HSPA4L,ZNF621,SATB2,ZMAT3,MTCH1,ZBTB38,WIPF2" MicroRNA hsa-miR-6716-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.45E-10 1.94E-06 5.28E-10 4.86E-09 23 96 "TPP1,PPP1R16B,USP6NL,SV2B,HEYL,IRAK4,AMOTL2,NEURL4,CECR2,DDX19B,KCNK1,GLIPR1L2,CNTLN,TMEM145,GTDC1,MYH14,NMNAT2,FGD4,MTMR14,CBX5,WBP2,UBC,UBTF" MicroRNA hsa-miR-552-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.46E-10 1.94E-06 5.28E-10 4.87E-09 31 167 "PNMA8B,TXNDC16,AK2,TAOK1,PHF12,TTLL9,DIRAS1,RUNX1T1,CD81,PLAA,BTF3L4,SOCS5,IRAK4,MRNIP,ERBB2,TUBA1B,ZNF44,GABRB3,KIF3A,GPR137C,PFKFB2,PKM,C12orf49,FOXRED2,HSPA4L,SGK1,DIP2A,ARL10,NACC2,MPPE1,AP3B2" MicroRNA "AGTTCTC,MIR-146B:MSigDB" "AGTTCTC,MIR-146B:MSigDB" MSigDB 3.60E-10 2.02E-06 5.51E-10 5.07E-09 17 52 "PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP1,USP3,PHF20L1,KDM2B,MMP16,NOVA1,KCTD15,ZNF532,SNX22,SYT1,POLR3H" MicroRNA "AGTTCTC,MIR-146A:MSigDB" "AGTTCTC,MIR-146A:MSigDB" MSigDB 3.60E-10 2.02E-06 5.51E-10 5.07E-09 17 52 "PRX,CASK,NUMB,NRP2,JAZF1,RUNX1T1,DLGAP1,USP3,PHF20L1,KDM2B,MMP16,NOVA1,KCTD15,ZNF532,SNX22,SYT1,POLR3H" MicroRNA hsa-miR-3922-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.69E-10 2.07E-06 5.63E-10 5.19E-09 20 73 "ADCY2,ADCY5,INTS2,SLC24A2,SUMF2,LETMD1,SCML2,SLC37A3,TACC2,IBA57,KSR2,SDK2,PPP3CC,PSD,KIF21B,TMEM178B,TAL1,NSD1,NR2E1,ZNF70" MicroRNA hsa-miR-4639-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.76E-10 2.11E-06 5.75E-10 5.29E-09 33 187 "TEX22,MTA3,PHF12,RGS6,LONRF1,DBT,TMCC2,COQ7,SRARP,GABRG2,CNDP1,KAT7,ATOH8,ZDHHC15,NKD1,PABPC1L2A,SH3TC2,C12orf49,ELP2,CHD9,ZFP1,ANKRD36,ZC3H13,SS18,INKA2,KLHL4,FBXL16,BHLHB9,SMUG1,UBE2H,ZNF708,PMEPA1,GAN" MicroRNA hsa-miR-3156-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-10 2.24E-06 6.09E-10 5.61E-09 26 122 "RNF150,MTA3,OSBPL1A,PHF12,AMER3,BACH1,CAMK2G,FGFR1OP2,IP6K1,CELSR3,MRPL37,GABRB1,POLL,KIF3A,MN1,CNNM2,PTAFR,SH3TC2,SPIN3,STUM,KIF21A,KANSL3,ZCCHC24,SMOC1,DPYSL5,GAN" MicroRNA hsa-miR-6885-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.08E-10 2.29E-06 6.22E-10 5.73E-09 24 105 "SLC12A5,TXNDC16,TRMT9B,PRX,ARHGDIA,BCL7A,NEURL1,ZNF385A,PYGO1,ERBB2,WAC,MTHFD2,GFER,NFIX,PLEC,SDK2,HSD11B1L,SMTN,NMNAT2,USP22,RBFOX2,UBTF,MGAT5B,VGF" MicroRNA "ACCAATC,MIR-509:MSigDB" "ACCAATC,MIR-509:MSigDB" MSigDB 4.14E-10 2.33E-06 6.31E-10 5.82E-09 16 46 "MMD2,GAD1,MEIS1,OLR1,ENPP2,PLP1,USP47,SOX2,PRRC2C,PCDHAC2,PCDHA7,PCDHA6,PCDHA5,PCDHA3,PCDHA2,PCDHA1" MicroRNA hsa-miR-4774-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.14E-10 2.33E-06 6.31E-10 5.82E-09 16 46 "LONRF2,SLC24A2,PHF19,RBPJ,KIT,LIMS1,MAT2A,ZNF426,PTPRE,ZNF793,C12orf49,SMARCE1,TPD52,ZNF781,WNK1,MPPE1" MicroRNA hsa-miR-6894-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.34E-10 2.44E-06 6.62E-10 6.10E-09 33 188 "ADAR,ANK1,APAF1,ARHGDIA,SUMF2,CS,CSF1,TOMM20,TMTC1,GLYR1,ZBTB45,HMX1,NEGR1,KIF5A,MAT2A,KSR2,PKM,SMIM7,PLXNB1,PACSIN1,POLG,PPP2R5E,MTMR10,RAB5B,MSANTD2,KLHDC8A,SOX11,PEG10,DBNDD2,AHCYL2,WBP2,WRN,ZNF17" MicroRNA hsa-miR-212-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-10 2.46E-06 6.68E-10 6.15E-09 30 159 "ZNF578,MTMR9,CACNA1A,CCNT1,RAB3C,COL9A2,FRMPD4,DNAL1,RAB30,GNAS,HMGB1,NASP,NFIX,PIK3C2A,ZNF426,C12orf49,ZNF568,STX1B,DRAXIN,HSPA4L,TRIM67,CLUAP1,POGZ,TMEM178B,WWC1,GPRIN3,ZNF34,NACC2,TJP1,ZNF70" MicroRNA hsa-miR-873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.38E-10 2.46E-06 6.68E-10 6.15E-09 30 159 "CC2D2A,TRMT9B,COL9A2,SOCS5,GAPVD1,HEPH,MTX3,ABCC5,EGR3,DCTN4,ZNF549,ZBED3,GABRB1,SIGLEC8,FAXC,SESN1,DDX19B,KCNN3,NUCB1,OLR1,GPR173,CCSER2,STK32A,ZNF331,SEPHS1,ERBIN,USP22,RPL7L1,VSNL1,PHTF2" MicroRNA hsa-miR-29b-3p:Functional MTI Functional MTI miRTarbase 4.65E-10 2.61E-06 7.08E-10 6.52E-09 40 261 "AQP4,FMNL3,CDC42,COL4A5,HDAC4,ELMSAN1,HP1BP3,FEM1B,SH3GLB1,GOLGA7,RACK1,DOT1L,CECR2,CIT,HMGCR,LAMA2,LIMS1,MYCN,NASP,PDGFRA,ENPP2,PIK3R1,KCTD15,GTDC1,GLDN,S100B,SLC30A10,SFPQ,SCAF8,SGK1,SEC31A,TET1,MAPKBP1,HECW1,KIF1B,ZFP91,TPD52L2,RUNDC3B,TUBB2A,TMEM237" MicroRNA hsa-miR-4659b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-10 2.70E-06 7.32E-10 6.75E-09 20 74 "SERPINA3,CD38,PITPNM3,BOC,DBN1,EBF1,BRPF3,ZNF274,GPR26,RAB41,FAM98B,GDPD1,NWD1,SALL1,SEPHS1,BTBD7,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-4659a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-10 2.70E-06 7.32E-10 6.75E-09 20 74 "SERPINA3,CD38,PITPNM3,BOC,DBN1,EBF1,BRPF3,ZNF274,GPR26,RAB41,FAM98B,GDPD1,NWD1,SALL1,SEPHS1,BTBD7,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-4795-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.82E-10 2.71E-06 7.33E-10 6.75E-09 26 123 "CNRIP1,CSNK1G3,SLC12A6,FOXO3,FYB1,GABRA4,TNRC6A,ZNF638,GRIK5,NR3C1,IL6R,MYCN,NPTX1,SNX10,MAPK8,SETD5,TMEM100,CSRNP3,ATXN1,SON,MYCBP2,KIF1B,CBX5,NR2C2,WNK1,ZXDA" MicroRNA hsa-miR-1914-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.85E-10 2.73E-06 7.39E-10 6.80E-09 28 141 "PNMA8B,ARRB2,ASPH,MTMR3,FOXK1,ARHGEF2,EVI5L,NOS1AP,IP6K1,SPATA2,RPS6KL1,ABCC5,EIF1,DMTN,SEPT9,RNF165,MMP17,NFIX,OGDH,OLR1,HSD11B1L,SLC2A5,RAP1GAP2,TAB2,CAMTA2,SEPT8,AJAP1,RPL7L1" MicroRNA hsa-miR-515-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.01E-10 2.81E-06 7.62E-10 7.02E-09 33 189 "GPR158,TNRC6C,ATP1B3,CACNA1A,SLC24A2,BTF3L4,NRG2,FAM131B,FGFR1OP2,FRMPD4,NR1D2,CELF1,DKK3,CAB39,GPD1,RABL2A,PTGDR2,CELF5,IL6R,MYO5A,PDE1A,PRKAB2,CYB561D1,PCMTD2,ATXN1,ATXN7,SNAP25,ZNF621,GANAB,SGK3,ZNF138,WNK2,ZNF248" MicroRNA "ATCATGA,MIR-433:MSigDB" "ATCATGA,MIR-433:MSigDB" MSigDB 5.02E-10 2.82E-06 7.64E-10 7.03E-09 24 106 "CSMD3,MIER1,FOXN3,NMT2,HP1BP3,CEP170,WDR20,ARRDC4,PHF20L1,PPARGC1A,PCDH11X,PTPRT,JAK2,KCNMA1,MARK3,MXI1,TTC13,KCNIP2,KIF16B,SLA,EPN2,PDZRN3,ANKRD12,STMN4" MicroRNA hsa-miR-6742-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-10 3.01E-06 8.15E-10 7.51E-09 23 98 "TRMT9B,AMPD3,TMEM184B,PYGO1,IP6K1,ELN,RNPS1,IBA57,MAP4,NFIX,TBC1D25,PLEC,EPN1,SLC25A23,SDK2,FOXRED2,ATXN2,PEX26,SMTN,PEG10,ARC,NACC2,UBTF" MicroRNA hsa-miR-196b*:mirSVR_highEffct hsa-miR-196b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.36E-10 3.01E-06 8.15E-10 7.51E-09 23 98 "FAHD2CP,UPRT,ASPH,ERC2,ELAVL4,ZIC4,NELFCD,FAM120B,PCDH17,COPS8,LINC01551,IL11RA,NRCAM,MAPK9,PTPRE,SEC61A2,DZIP1,PAAF1,SCMH1,SOX3,C12orf76,GZF1,XPO1" MicroRNA hsa-miR-375:mirSVR_highEffct hsa-miR-375:mirSVR_conserved_highEffect-0.5 MicroRNA.org 5.47E-10 3.07E-06 8.32E-10 7.66E-09 31 170 "BEND6,LRFN1,OGT,APBB2,EIF4G3,RAB33A,CNN3,PNPLA8,SH3GLB1,ELAVL4,VPS13B,GPHN,CACNG2,SYNCRIP,STAMBP,OGA,GGTA1P,RBPJ,P2RX7,PCSK5,WBP1L,OXR1,ROBO2,FUZ,TET1,UHRF1BP1L,NPAS3,CLASP2,ZFPM2,TRIM9,XKR7" MicroRNA hsa-miR-4802-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.48E-10 3.08E-06 8.33E-10 7.68E-09 22 90 "ANK1,DOCK11,BACH1,RUNX1T1,CCNT1,HECTD1,NCOR2,DNAL1,SPATA2,ZBTB45,HSF2,KCND3,NAP1L1,SMIM7,CNNM2,RAB5B,CEP97,SLITRK3,PEG10,ZSCAN29,ZC3H4,ZFP91" MicroRNA hsa-miR-525-3p:mirSVR_highEffct hsa-miR-525-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.80E-10 3.26E-06 8.81E-10 8.12E-09 26 124 "PCDH10,AMPD3,API5,NUMB,QKI,MICAL2,GOLT1B,EBF1,FCGRT,ATP2C1,COPS8,AQP11,NF1,NTRK3,GPR88,GTDC1,KIAA0895L,HSD11B1L,SH3BGR,ITSN1,SLIT1,ZC3H13,DDN,ADGRL3,MTMR14,CSDE1" MicroRNA hsa-miR-3925-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.87E-10 3.30E-06 8.91E-10 8.21E-09 27 133 "NCKAP5,TNRC6C,SOCS6,TENM4,FAM131B,TMCC2,NR1D2,CELF5,SOWAHA,KIAA1755,SCRT2,ZNF678,CREG2,A2ML1,ELP2,NCBP3,RADIL,ZNF667,SNAP25,INKA2,APOM,NSFL1C,TMEM151B,PLPP4,ZNF138,WNK2,SPATA13" MicroRNA hsa-miR-3195:mirSVR_lowEffct hsa-miR-3195:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 5.87E-10 3.30E-06 8.91E-10 8.21E-09 27 133 "PPFIA3,ASGR1,KSR1,COG1,SULT4A1,MAGI2,BRPF3,STARD3,DCLK2,GP1BB,CLASRP,CELF5,IL11RA,GIT1,ZNF862,CDK18,PFKFB4,NECAB2,RFX2,NTNG1,SLC11A1,NAXD,ADHFE1,HIF3A,STMN4,CASC15,JPH3" MicroRNA hsa-miR-663:PITA hsa-miR-663:PITA_TOP PITA 5.98E-10 3.36E-06 9.08E-10 8.36E-09 16 47 "DPF1,CSMD2,SLITRK1,SLC12A5,ZNF385A,GRIN2D,CAMK2N2,MAPT,MDGA1,NFIX,PPP5C,BTBD3,NCDN,C3orf70,SZT2,AMACR" MicroRNA "CAGTCAC,MIR-134:MSigDB" "CAGTCAC,MIR-134:MSigDB" MSigDB 5.98E-10 3.36E-06 9.08E-10 8.36E-09 16 47 "ASIC1,CSNK1G3,CPEB2,ILDR2,TTBK1,GNAO1,KAT7,MAT2A,MBNL1,MYCN,OPCML,MTCL1,ADGRL3,PSD3,ZFPM2,SMARCAD1" MicroRNA hsa-miR-1275:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.00E-10 3.37E-06 9.11E-10 8.39E-09 30 161 "TAOK1,ANK1,ARHGDIA,CAMK2A,METTL6,DLGAP3,CLU,TMEM184B,PLEKHM1,EFNA3,ANKRD13B,PRRC2B,KCNH2,CHST6,NFIX,PKM,SPATA6,PTPA,DIRAS2,MYH14,HSD11B1L,ZFP30,PKNOX2,FNBP1,NMNAT2,RAP1GAP2,UBTF,MEAF6,CLIP2,RICTOR" MicroRNA hsa-miR-1237-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-10 3.46E-06 9.34E-10 8.60E-09 24 107 "SLC12A5,BCL7A,EVI5L,CBARP,CLU,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NEUROD2,NFIX,NRGN,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA hsa-miR-924:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-10 3.46E-06 9.34E-10 8.60E-09 24 107 "VXN,ISPD,TBRG4,BTF3L4,RTTN,PPP1R16B,ST18,DBT,APH1A,C1orf61,SRCAP,PLD5,MOG,PIK3R1,KANSL1,PTPRB,ZYG11B,ELMOD1,HSPA4L,SHMT2,ST6GAL1,SEPHS1,FAM126B,TMEM136" MicroRNA hsa-miR-453:PITA hsa-miR-453:PITA_TOP PITA 6.25E-10 3.51E-06 9.47E-10 8.72E-09 20 75 "PTBP2,CAMK2B,DNAJB5,ST18,DLG2,CALCRL,PAN3,INSM1,MXI1,NDP,PLP1,FAM120C,SOX6,ERC1,NPAS3,FBXW11,TCF12,RALYL,LRRC8A,FMN2" MicroRNA hsa-miR-363-3p:Functional MTI Functional MTI miRTarbase 6.36E-10 3.57E-06 9.64E-10 8.88E-09 47 342 "SLC12A5,CASKIN1,USP28,ADAM15,CDK5R1,CLTA,TMEM184B,HP1BP3,MRO,PLEKHA1,EIF1,KIAA1109,GAP43,KIAA1958,PRRC2B,LILRA2,TPPP,AGBL5,EID2B,C5orf24,ZIC5,RBPJ,IL6ST,SESN3,CNOT4,PIK3CD,CCSER2,ZFYVE21,PURG,TATDN3,UHRF1BP1,MTMR10,REV3L,SLC25A36,FBXW7,FNIP1,CPEB3,ATF7IP,CPEB4,SOX11,MCF2L2,ITPRID2,RBFOX2,ZNF24,PMEPA1,MFF,XKR7" MicroRNA hsa-miR-3658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.46E-10 3.63E-06 9.79E-10 9.02E-09 29 152 "TAOK1,ZBTB10,LDLRAD4,LIN54,TOMM20,SCRN1,ABI2,EIF4G2,TENM1,WAC,ACSL4,MIER3,LIFR,ARHGAP12,NCAM2,PIK3R1,EPB41L4B,GDPD1,ZNF844,CEP97,SETD5,BTBD7,TMCC1,ITPRID2,LEFTY2,TLR4,UGT8,MPPE1,FZD3" MicroRNA hsa-miR-1257:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.70E-10 3.76E-06 1.02E-09 9.35E-09 25 116 "ABCD2,CDC14B,SPAG9,FOXN3,AKAP6,SLC35F1,EIF5,ZNF585B,ATP13A4,CRCP,CLVS2,LYPLAL1,ST8SIA5,ZNF844,GTDC1,ELP2,MCMBP,ZFP1,ZNF415,SPART,SYPL1,TNR,VSNL1,ZNF138,ZNF195" MicroRNA hsa-miR-5195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.78E-10 3.81E-06 1.03E-09 9.45E-09 21 83 "SMIM17,THSD7A,ZNF445,ZFYVE9,UBXN2A,PLEKHM1,NR1D2,EID2B,ZNF678,ZNF426,PNMA3,PSAT1,UBR7,ALG9,CSRNP3,CLSTN2,ANKRD28,UNC5D,TNR,TPM3,PRDM2" MicroRNA hsa-miR-126:mirSVR_lowEffct hsa-miR-126:mirSVR_conserved_lowEffect-0.1-0.5 MicroRNA.org 6.89E-10 3.87E-06 1.04E-09 9.60E-09 22 91 "ARNTL,SRSF11,CHN2,SLC32A1,ARMCX1,FAM198B,ERAP1,TNRC6A,GRIA2,GRIA4,GRM3,PCDH9,PEX5,RORB,CCDC102B,GALNT10,PPP4R3A,PDZRN3,SOX2,TP53BP2,TSC1,ADAMTS9" MicroRNA hsa-miR-4480:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.97E-10 3.92E-06 1.06E-09 9.72E-09 26 125 "NDRG3,ADCYAP1R1,GPAM,ZBTB10,RGS6,RASSF2,ZNF391,ATP13A4,GATM,CIT,AFF1,SDK2,MAPK8,C1orf109,TMEM231,ACSS3,SLC25A36,RNASEL,KCNIP2,SNAP25,DDN,STAC2,TCEA1,ANKRD24,FXR1,NETO2" MicroRNA hsa-miR-548at-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.97E-10 3.92E-06 1.06E-09 9.72E-09 26 125 "TAOK1,ZBTB10,DDX3Y,PTBP2,DNAL1,RCAN2,POLR1B,FUT10,MAP4K5,MAT2A,MMP16,CEP97,ROBO1,SON,TROVE2,ANKRD28,FAM208A,SIRT1,NACC2,CBX5,RFTN2,NSD2,ZNF70,ZNF138,DHX33,PMEPA1" MicroRNA hsa-miR-6730-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-10 3.92E-06 1.06E-09 9.72E-09 19 68 "CCNT1,PPP1R16B,NOS1AP,KIAA0408,MTX3,RPS6KL1,ERBB2,SMC2,PLD5,METTL21A,LSAMP,CHIC1,MPP2,ALDH1L2,PKD1,OXR1,TMEM200C,SMOC1,TMEM151B" MicroRNA hsa-miR-3139:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-10 3.92E-06 1.06E-09 9.72E-09 19 68 "PLEKHG5,NOS1AP,CTIF,TUBB4A,PCYOX1,AHDC1,PRRC2B,RNF165,KCNH2,KLHL11,DRAXIN,MYH15,IQSEC2,FAM168A,THRA,ZFP91,TUBB2A,PRDM2,PIANP" MicroRNA hsa-miR-4313:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.98E-10 3.92E-06 1.06E-09 9.72E-09 19 68 "PLEKHG5,SLC12A5,KIF6,LRFN1,HCN2,NCOR2,G3BP2,MUM1,ITPKB,XRRA1,NODAL,PDE4A,ZDHHC8,PIGG,AJAP1,GSE1,TOM1L2,VANGL2,PIANP" MicroRNA hsa-miR-505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.00E-10 3.93E-06 1.06E-09 9.74E-09 27 134 "LTBP4,CCAR2,CAMK2A,RUNX1T1,NRXN3,TMEM184B,ATN1,APC2,TBC1D16,TUBA1B,GTF2IRD2,NSG2,MAP7D2,GPER1,TNFAIP8L3,PLD5,CHST6,OCRL,POLR2F,PTPA,PEAR1,TRIM67,KDM4B,SATB2,TMEM9,ZFP91,CIAPIN1" MicroRNA hsa-miR-216a-5p:Functional MTI Functional MTI miRTarbase 7.01E-10 3.94E-06 1.06E-09 9.75E-09 30 162 "CLK4,AS3MT,MTA3,APAF1,CDC42,CPS1,UBXN2A,MRNIP,COQ7,SEC23B,ZNF638,KDM2B,RFFL,JAK2,PPM1L,MITF,A2ML1,SMIM7,CNNM2,ZNF793,ATF7IP,SP4,ELOVL4,TMEM178B,ALG1,WWC1,SLC19A3,PSD3,SIRT1,TUBB2A" MicroRNA hsa-miR-4665-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-10 3.94E-06 1.06E-09 9.75E-09 30 162 "TAOK1,ANK1,ARHGDIA,CAMK2A,METTL6,DLGAP3,CLU,TMEM184B,PLEKHM1,EFNA3,ANKRD13B,PRRC2B,KCNH2,CHST6,NFIX,PKM,SPATA6,PTPA,DIRAS2,MYH14,HSD11B1L,ZFP30,PKNOX2,FNBP1,NMNAT2,RAP1GAP2,UBTF,MEAF6,CLIP2,RICTOR" MicroRNA hsa-miR-367-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-10 3.94E-06 1.06E-09 9.75E-09 30 162 "ABCF1,AS3MT,ESYT2,ISPD,ZFYVE9,AKAP5,YAF2,MRNIP,COQ7,RTN3,SYNCRIP,LILRA2,GPR45,SCIN,IBA57,GPR155,MKLN1,ZNF713,PDE3A,OLA1,RAVER2,ELP2,RYR3,HSPA4L,ZFP30,PEX26,ANKRD36,FAM126B,ZNF154,RNF170" MicroRNA hsa-miR-1228-3p:Functional MTI Functional MTI miRTarbase 7.20E-10 4.04E-06 1.09E-09 1.00E-08 39 254 "PLEKHG5,APAF1,ATP1B3,BCL2L2,CA8,PLAA,STOML1,HP1BP3,EDIL3,SORBS3,EPB41,SLC43A2,MRPL10,TLR7,CEP78,POLR1B,FOXF2,FOXO3,MSANTD4,ZNF274,GRIK3,KIF3A,FAM107A,ITPKB,PPM1L,AFF1,JAKMIP3,ZC3H12B,APTX,PTPRN2,NWD1,DCUN1D2,ATXN1,SEPHS1,SCN3B,CLUAP1,NFASC,ZSCAN29,RFTN2" MicroRNA hsa-miR-3973:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.59E-10 4.26E-06 1.15E-09 1.05E-08 29 153 "SDE2,SMIM17,PLEKHM1,DMD,HIPK3,FRY,CELSR3,ELAVL2,PLEKHA1,RGS17,COQ7,SCML2,SEMA4D,MSANTD4,CHST6,CCDC80,PPP2R5E,PROX1,KLHL11,ZNF354C,ATF7IP,CEP68,ATMIN,ARL10,TMPO,VLDLR,NSD2,ZBTB38,FXR1" MicroRNA hsa-miR-7854-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.59E-10 4.26E-06 1.15E-09 1.05E-08 29 153 "ARID1A,ASPH,CBS,CFL2,SUMF2,NOS1AP,DUSP9,TMTC1,APH1A,FGFR1,CELF1,PNMA2,NEURL4,CRCP,SLC6A17,DIRAS2,PTPRB,C12orf49,FAM102A,MAPKBP1,SOX11,SP2,DDN,NACC2,SSBP2,TUBB2A,PORCN,WIPF2,ZDHHC20" MicroRNA hsa-miR-2113:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.59E-10 4.26E-06 1.15E-09 1.05E-08 29 153 "CACNG1,BTF3L4,COL9A2,CLOCK,ZC3H11A,DMD,DYRK1A,AFF2,DOT1L,SALL3,SRRM4,SRCAP,CBX1,SCRT2,HECTD2,MITF,KSR2,PKIA,CNNM2,REV3L,CLIP1,ATXN1,MPRIP,ASTN2,ALG1,ZEB1,VSNL1,PORCN,SLC38A1" MicroRNA hsa-miR-4662a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.59E-10 4.26E-06 1.15E-09 1.05E-08 29 153 "TAOK1,C6orf89,VAT1L,API5,ZBTB10,DST,OSBPL3,UBXN2A,MTX3,FEM1B,ZIC4,TRAF3IP2,CRCP,GPR26,GRK4,SLC2A6,HCN1,OLA1,FAT3,ZYG11B,UEVLD,NCBP3,WDR37,SPART,ALG1,AKNA,ZNF70,DHX33,MSRB3" MicroRNA hsa-miR-874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.07E-10 4.54E-06 1.22E-09 1.12E-08 20 76 "TRMT9B,ANK1,BCL2L2,TOM1,MTSS1L,CEP78,TMEM151A,CYP27C1,NFIX,PDE4A,TNPO2,KCNIP3,SLC8A3,TRIM67,CLUAP1,MAPK8IP3,VAMP1,MGAT5B,INTS3,VANGL2" MicroRNA hsa-miR-4303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.22E-10 4.62E-06 1.24E-09 1.14E-08 23 100 "ARID1A,CST3,GREB1,TOMM20,SLC43A2,MRVI1,CAMSAP1,CELF1,HTR2A,BLOC1S2,NFIX,NPTX2,NUCB1,GPR173,PGBD4,SEMA6D,CSRNP3,FAM126B,KIF1B,NSD1,TUBB2A,ZNF74,ZXDA" MicroRNA hsa-miR-5683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.22E-10 4.62E-06 1.24E-09 1.14E-08 23 100 "ZNF608,RUNX1T1,HINFP,BLOC1S6,DLC1,SCARA3,MTHFD2,EML4,ELOVL5,DOCK7,KCNN3,PDE3B,PDPK1,KANSL1,RDX,RGR,KIF21A,ADAMTS17,SYT1,TCEA1,CBX5,USP1,MEAF6" MicroRNA hsa-miR-2110:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.33E-10 4.68E-06 1.25E-09 1.15E-08 27 135 "CACNB2,USP2,TPP1,NCOR2,MRO,HBS1L,SRCAP,GPR26,NXPH3,MIER3,SCIN,MSI1,NBL1,PFKFB2,FXYD1,EPB41L4B,WBP1L,KIAA0895L,SBF1,DRAXIN,COPZ1,UNC5B,POGZ,FAM168A,CBX5,ZNF708,CIAPIN1" MicroRNA hsa-miR-3173-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.33E-10 4.68E-06 1.25E-09 1.15E-08 27 135 "ARID1A,XKR4,SORCS2,ZNF578,TRMT9B,CDC14B,LIN54,CHRDL1,CACNG7,EN2,GJB1,NDUFA5,NOVA2,TMEM231,BSDC1,RUFY2,FAM168A,ASTN2,HHIP,NACC2,ASXL3,TPD52L2,TPM3,BCL2L13,WRN,ITM2C,SSPN" MicroRNA hsa-miR-7154-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.33E-10 4.68E-06 1.25E-09 1.15E-08 27 135 "CASKIN1,ARHGDIA,LDB2,CS,CSF1,EFNA3,GFRA1,ZBTB45,HMX1,NEGR1,KSR2,PKM,SMIM7,PLXNB1,PACSIN1,POLG,RAB5B,CLSTN1,SOX11,PEG10,DBNDD2,THRA,ERCC6L2,WBP2,WRN,KLC2,ZNF17" MicroRNA hsa-miR-493-3p:TargetScan hsa-miR-493-3p TargetScan 8.37E-10 4.70E-06 1.26E-09 1.16E-08 26 126 "KIAA1211,FUBP1,P2RX6,CDC27,QKI,COL9A2,FRMPD4,EARS2,JAKMIP2,DLG3,EPS8,MRVI1,CPLX1,RAB30,NCKAP1L,HTR2A,KCNJ9,KCNK10,PDE4D,GNG2,MDGA2,RORB,NFASC,ELP5,FAM219B,RSPRY1" MicroRNA hsa-miR-133b:Functional MTI Functional MTI miRTarbase 8.61E-10 4.83E-06 1.30E-09 1.19E-08 21 84 "CDK13,BCL2L2,HCN2,CDK5R1,PTBP2,CDC42,ZFP28,HAPLN1,EGFR,FGFR1,ITPKB,KCNH2,SESN3,PDE1A,PKM,ZMAT4,EMID1,SGK1,SIRT1,TPM3,NUP214" MicroRNA hsa-miR-627:PITA hsa-miR-627:PITA_TOP PITA 9.49E-10 5.33E-06 1.43E-09 1.32E-08 28 145 "DSCAML1,CACHD1,MTMR3,BSN,RUNX1T1,REPS2,NRXN1,AKAP7,TENM4,FRMPD4,NYAP1,CALN1,GOLT1B,RBM12,EFNB3,APH1A,RGS17,SRRM4,SOX21,ZC3H12B,NOVA1,KSR2,SEPT4,KANSL1,PPP4R3A,FAM214B,SOX11,RNF146" MicroRNA hsa-miR-339-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.52E-10 5.35E-06 1.43E-09 1.32E-08 37 235 "SLC24A4,KIF6,ZNF445,USP6NL,CENPL,TMEM170A,G3BP2,RCAN1,UFM1,BRSK1,RAPGEF1,GRIK4,GPR45,SYNPO,KCNH1,KCNJ11,MAP4,NOVA1,SLC11A2,KLHDC8A,NCBP3,TRA2B,AMBRA1,URGCP,SLC11A1,SOX11,SULF2,FGD4,FAM208A,SZT2,HHIP,CBX5,KCTD2,TPM3,NSD2,ZNF708,FAM219B" MicroRNA hsa-miR-885-3p:PITA hsa-miR-885-3p:PITA_TOP PITA 9.69E-10 5.44E-06 1.46E-09 1.34E-08 17 55 "DOC2A,MARK4,FMNL3,RIMS4,IP6K1,DYRK1A,CELF3,L1CAM,ZNF827,PPP3CB,SEC61A2,RAVER2,SMPD3,SMTN,ST5,TCF7,TNS1" MicroRNA hsa-miR-5589-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.80E-10 5.51E-06 1.47E-09 1.36E-08 25 118 "USP28,SLC7A14,FOXK1,CALM1,RASSF2,STARD3NL,KIAA1109,ZBED3,TPPP,EID2B,IL6ST,KCNB1,SESN3,HS6ST3,NPTX1,PROX1,PLEKHB2,NCBP3,CPEB4,SIN3B,NACC2,ZNF138,MFF,MVB12B,PHTF2" MicroRNA hsa-miR-4662a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-09 5.84E-06 1.56E-09 1.44E-08 20 77 "CALM1,CLTA,AMOTL2,FAXC,IGF1,KPNA5,NFIA,CCSER2,PURG,PPP2R5E,PXK,ZNF793,CNKSR2,ZBTB43,ERBIN,VAMP1,HHIP,NR2E1,TUBB2A,SPIRE1" MicroRNA hsa-miR-380-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-09 5.84E-06 1.56E-09 1.44E-08 20 77 "TNRC6C,CCDC74A,ANKRD44,FSD1L,EIF5,TUBD1,RAB9B,SCML2,MMADHC,C5orf24,SH3TC2,ALG9,PGBD4,FBXW7,SYPL1,TRPS1,ZFP37,FAM182B,HNRNPA3,NETO2" MicroRNA hsa-miR-3671:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-09 5.85E-06 1.57E-09 1.44E-08 29 155 "TXNDC16,CACNA1A,CREB5,ANKRD46,YAF2,COQ7,IQCG,MPP6,WASF3,SRCAP,TCERG1,TNRC6A,SNTG1,PDE3A,FAM98B,PPARA,RAD52,SH3TC2,TMLHE,FAM19A1,FAM126B,CLUAP1,PEG10,PRRC2C,FAM208A,FNDC5,ZNF225,SLC38A1,PRDM10" MicroRNA hsa-miR-744-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-09 6.04E-06 1.61E-09 1.49E-08 37 236 "AS3MT,TMEM132B,ESYT2,SLC7A14,ISPD,AKAP5,CSNK1G3,SEC14L5,KIAA0408,KLHL5,MRNIP,COQ7,DLC1,GLUL,LILRA2,GPR45,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,NUCB1,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,PEX26,FAM126B,PSD3,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA hsa-miR-4532:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-09 6.28E-06 1.68E-09 1.55E-08 28 146 "GPRIN1,RNF157,TXNDC16,LRFN1,CPNE5,CDC14B,SLC7A14,KIAA1614,KIAA0408,PHYHIP,SGSM2,SLC43A2,ECSIT,FKTN,PDLIM5,CRCP,RFFL,HMGB1,LIMS1,NEUROD2,NWD1,RGS12,RXRA,ZFP30,INKA2,TPCN2,AHCYL2,ZNF106" MicroRNA hsa-miR-3678-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-09 6.30E-06 1.68E-09 1.55E-08 24 110 "IGDCC4,EPS15L1,CLU,CLTA,CPS1,DCC,APH1A,SLC43A2,GABRB3,COPS8,TNRC6A,RNF165,ATOH8,PADI2,ZNF678,IPO5,TMEM104,SH3TC2,SLC25A36,GSTCD,SON,IQCE,PMEPA1,GAN" MicroRNA hsa-miR-100-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-09 6.30E-06 1.68E-09 1.55E-08 24 110 "ASPA,STX16,SRSF11,CNN3,CNRIP1,NECTIN3,TENM4,PLCXD3,KATNAL1,FOXO3,GABRB1,IL1RAPL1,SYT9,THYN1,PURG,PACSIN1,FAM161B,SGK1,SON,SOX3,ZHX3,SYPL1,BCL2L13,VLDLR" MicroRNA hsa-miR-302d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-09 6.30E-06 1.68E-09 1.55E-08 24 110 "USP37,APP,TMEFF1,CLOCK,MYADM,SCRN1,SPATA2,JAKMIP2,TBC1D16,FGF1,AMOTL2,GPR75,TNRC6A,HMGB1,DIPK1A,MSANTD3-TMEFF1,LSAMP,OLA1,ZNF793,FNDC3A,BTBD7,EML6,DHX33,PMEPA1" MicroRNA hsa-miR-6165:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-09 6.59E-06 1.76E-09 1.62E-08 27 137 "GRAMD1B,SFMBT2,ASPH,ZBTB10,CS,NCAN,PPP1R16B,UBXN2A,RUBCN,IST1,HEYL,DCTN4,POLR1B,ATOH8,KIF5A,PPM1L,CNNM2,ALG9,NCBP3,SEMA6D,ZC3H4,SLC19A3,HIF3A,NACC2,LRTM2,RPRM,VAV2" MicroRNA hsa-miR-211-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.18E-09 6.64E-06 1.77E-09 1.63E-08 25 119 "OGT,ARHGDIA,FMNL3,SV2B,ABI2,ERBB2,GABRA5,RAPGEF1,IGF1,LRRC4B,COMMD5,NUMA1,PCSK2,RETREG2,SLC6A1,DDN,SLC37A2,ATP11A,CAMSAP2,TMEM151B,PUM2,TPD52L2,PPIL6,SLC30A3,RNF146" MicroRNA hsa-miR-193a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.20E-09 6.72E-06 1.79E-09 1.65E-08 26 128 "AK2,E2F6,SEMA3D,ABI2,ASB3,COQ7,ERBB2,ERBB4,ANKFY1,KIAA1841,CACFD1,HMGB1,NF1,OPHN1,PPP2R5C,MAPK8,PTK2,MSANTD2,RTKN,ELMO2,TCF7L2,ZMAT3,TNFRSF1B,ZNF384,RGMA,RNF146" MicroRNA hsa-miR-4280:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-09 6.74E-06 1.80E-09 1.66E-08 19 70 "USP37,ARNTL,BACH1,EVI5L,HECTD1,CSNK1G3,UBXN2A,GAPVD1,DNAJB6,EIF5,SCML2,GNAS,KAT7,MAPK8,PEX26,SP4,TROVE2,VLDLR,ZNF24" MicroRNA hsa-miR-550a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-09 6.79E-06 1.81E-09 1.67E-08 16 49 "FEM1B,TUBD1,SYNCRIP,HSP90AA1,C2orf72,EFHB,MOG,SLC11A2,POLR2F,PKIA,MAPK3,ZYG11B,ZNF621,TPM3,HPS4,URM1" MicroRNA "GGTAACC,MIR-409-5P:MSigDB" "GGTAACC,MIR-409-5P:MSigDB" MSigDB 1.22E-09 6.83E-06 1.82E-09 1.68E-08 13 31 "CAMK2G,DYRK1A,KMT5B,RASL12,STAG2,GPM6A,KLF12,PURG,KIF1B,TRPS1,ZIC1,ZIC3,TRIM9" MicroRNA hsa-miR-3193:mirSVR_highEffct hsa-miR-3193:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.32E-09 7.38E-06 1.97E-09 1.81E-08 28 147 "KCNAB2,SEMA4G,BID,CACNB2,CBR1,BTF3L4,SNCAIP,CSF2RA,ARHGAP24,DDX46,PAN3,ARPP21,EML4,ADAMTS6,SMAP1,CTNNA3,TBC1D25,PLXNB3,MED1,UEVLD,LGR4,ABCA11P,CDK5RAP2,KDM4B,PEG10,AKTIP,LRTM2,ZBTB16" MicroRNA hsa-miR-6857-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-09 7.65E-06 2.04E-09 1.88E-08 24 111 "ELFN2,CBARP,MICAL2,KIAA0040,DBN1,ZC3H11A,MTX3,MRNIP,FGF1,TDRKH,RNF165,DDR2,NUCB1,PDE4D,KCTD15,ATP8B4,FAM126B,ZNF621,SMOC1,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-4423-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-09 8.77E-06 2.33E-09 2.15E-08 19 71 "SDE2,CLOCK,IP6K1,VTI1B,ZBED3,GABRB1,FERMT2,NR3C1,NCAM2,CNNM2,ATAT1,ATXN1,SLC8A1,TBX15,FRRS1L,OSBP2,NSD2,WRN,CLDND1" MicroRNA hsa-miR-4645-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-09 8.77E-06 2.33E-09 2.15E-08 19 71 "MARCH4,ARRB2,SPATA2,PLEKHM1,G3BP2,RPS6KL1,HIPK3,RASGRP1,AMOTL2,TMEM151A,B4GALNT1,SRCAP,MYO5A,ZNF354C,RMI1,TMEM151B,ZFP91,SLC30A4,WNK3" MicroRNA hsa-miR-6823-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-09 8.77E-06 2.33E-09 2.15E-08 19 71 "HECW2,LONRF2,SPATA2,C2CD2L,TMCC2,FAM135B,MTSS1L,FABP7,CELF1,TDRKH,KAT7,NEGR1,PLD5,NCR3LG1,ATXN2,ASIC4,PKNOX2,PEG10,WNK1" MicroRNA hsa-miR-566:mirSVR_highEffct hsa-miR-566:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.56E-09 8.77E-06 2.33E-09 2.15E-08 19 71 "ADAM15,CAMK2G,IGFBP7-AS1,EIF1,DLC1,GABRB3,SESN1,INSM2,LOXL3,PLCD4,GIT1,PIGG,PEG10,CAMTA2,UGT8,OSBP2,TRIM9,MPPE1,SSPN" MicroRNA hsa-miR-4738-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-09 9.27E-06 2.47E-09 2.27E-08 24 112 "FAM43B,FZD9,NUMB,SRSF11,MFSD4A,C2CD2,SEC14L5,GFRA1,PTPRT,FICD,IL6R,SH3TC2,IL17RB,MBD5,MCF2L2,DDN,NEK4,KLHL7,C3orf70,DDHD2,TLR4,FMN2,ZFAND5,MFF" MicroRNA hsa-miR-548m:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-09 9.30E-06 2.48E-09 2.28E-08 22 95 "PCDH19,TNRC6C,CA12,LONRF2,CLCN3,CTNND1,PCDH17,RNPS1,PRUNE2,FUT10,BLOC1S2,OPHN1,PCDH9,CNTLN,PXK,CSRNP3,TAB2,MPRIP,SYT4,RPRM,SLC38A1,HNRNPA3" MicroRNA hsa-miR-99b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-09 9.52E-06 2.53E-09 2.33E-08 16 50 "GRAMD1B,PUM1,KIAA0319,ABI2,GSTM5,MAP4,MMP16,PPP5C,ZNF793,KIRREL1,DZIP1,ZNF621,AGTPBP1,CCDC14,WIPF1,WIPF2" MicroRNA hsa-miR-4251:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-09 9.57E-06 2.55E-09 2.35E-08 25 121 "KLHL32,PLEKHG5,MIER1,BACH1,MICAL2,KIAA0040,SLC43A2,MRVI1,AMOTL2,PRRC2B,LRRC75A,HTR2A,NUCB1,GPR173,KCTD15,PRKAB2,KCNIP2,CSRNP3,ZNF621,TMEM136,PRMT8,TUBB2A,ZNF45,ZNF74,URM1" MicroRNA hsa-miR-202-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-09 9.67E-06 2.57E-09 2.37E-08 21 87 "ZNF578,GAS7,RUNX1T1,LONRF2,CNN3,USP3,COQ7,COPS8,ZDHHC15,IBA57,SESN3,PKN2,MARCH1,ZFP30,PRRC2C,ATP11A,TRPS1,RICTOR,FAM13C,FXR1,JPH3" MicroRNA hsa-miR-4258:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.72E-09 9.67E-06 2.57E-09 2.37E-08 21 87 "MARCH4,DIRAS1,ZMYM4,NUMBL,CBARP,ZNF385A,TUBD1,EPB41L1,SLC43A2,FDFT1,NCKAP1,GFER,KIAA1958,KIFC3,MAT2A,RXRA,SEPT8,STAC2,WWC1,SSBP2,SF1" MicroRNA hsa-miR-1251-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-09 9.75E-06 2.59E-09 2.39E-08 18 64 "BCL7A,FOXK1,CAMK2A,RTTN,PPP1R16B,SPATA2,CHRDL1,ANKMY1,AMOTL2,MSANTD4,GABRB1,SRCAP,OCRL,C1orf109,RDX,NLGN1,ASTN2,SMARCAD1" MicroRNA hsa-miR-4697-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-09 1.05E-05 2.79E-09 2.57E-08 23 104 "SLC12A5,BCL7A,EVI5L,CBARP,CLU,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NEUROD2,NFIX,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA hsa-miR-449b-5p:Functional MTI Functional MTI miRTarbase 1.93E-09 1.09E-05 2.88E-09 2.66E-08 27 140 "PDXK,ZMYM4,EVI5L,FOXN3,PHF19,CTIF,MRNIP,APOPT1,POLL,FICD,DDX19B,MAP4,MDM4,MKLN1,MYCN,NEUROD2,CNOT4,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,SIRT1,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-449c-5p:Functional MTI Functional MTI miRTarbase 2.00E-09 1.12E-05 2.97E-09 2.74E-08 24 113 "PNMA8B,SHROOM2,ZNF582,BTRC,EVI5L,UBXN2A,EBI3,VTI1B,TMEM151A,NEURL4,GABRB1,MALT1,FERMT2,ZNF546,KCND3,KCNJ11,MAP4,CNOT4,POLR2F,ATXN1,TROVE2,ZSCAN29,CAMSAP2,ZNF708" MicroRNA hsa-miR-302b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.00E-09 1.12E-05 2.97E-09 2.74E-08 24 113 "USP37,APP,TMEFF1,CLOCK,MYADM,SCRN1,SPATA2,JAKMIP2,TBC1D16,FGF1,AMOTL2,GPR75,TNRC6A,HMGB1,DIPK1A,MSANTD3-TMEFF1,LSAMP,OLA1,ZNF793,FNDC3A,BTBD7,EML6,DHX33,PMEPA1" MicroRNA hsa-miR-4524a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-09 1.13E-05 3.00E-09 2.76E-08 32 189 "TAOK1,TRMT9B,CASK,MTMR3,FOXK1,CA8,CANX,CCNT1,DLGAP3,SOCS5,YTHDC1,DMTF1,PLEKHA1,MYO5A,OCRL,PIK3R1,PSAT1,PPP2R5C,MAPK8,CNNM2,PTPRD,ZFHX4,TMEM100,ZC3H14,SALL1,ATXN2,KANK1,ZMAT3,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-4524b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-09 1.13E-05 3.00E-09 2.76E-08 32 189 "TAOK1,TRMT9B,CASK,MTMR3,FOXK1,CA8,CANX,CCNT1,DLGAP3,SOCS5,YTHDC1,DMTF1,PLEKHA1,MYO5A,OCRL,PIK3R1,PSAT1,PPP2R5C,MAPK8,CNNM2,PTPRD,ZFHX4,TMEM100,ZC3H14,SALL1,ATXN2,KANK1,ZMAT3,XKR7,WNK3,RTN4,ACTR3B" MicroRNA hsa-miR-204-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-09 1.13E-05 3.00E-09 2.77E-08 26 131 "MYOM2,COL9A2,RGS6,ASB3,VPS26C,AMOTL2,MTHFD2,CRCP,GLUL,POLL,LILRA2,BVES,NEGR1,ATCAY,KCNK1,KCTD15,KIAA0895L,PEX26,NFASC,NXT2,AJAP1,FGD4,CBX5,BHLHB9,ZBTB38,XKR7" MicroRNA hsa-miR-496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-09 1.15E-05 3.04E-09 2.80E-08 25 122 "KIF6,BACH1,CD86,DLGAP3,CPS1,ST18,SGIP1,SMC2,NR3C1,ZIC5,SFXN5,SESN3,NPTX1,SNX10,ZNF426,MAPK8,NKAIN1,ZNF793,SH3TC2,TMLHE,PEX26,TMCC1,MYCBP2,TACC1,ZFAND5" MicroRNA hsa-miR-367-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-09 1.15E-05 3.05E-09 2.81E-08 45 331 "SLC12A5,CASKIN1,USP28,CDK5R1,CLTA,TMEM184B,HP1BP3,MRO,PLEKHA1,EIF1,KIAA1109,KIAA1958,PRRC2B,LILRA2,TPPP,AGBL5,EID2B,C5orf24,ZIC5,RBPJ,IL6ST,SESN3,CNOT4,PIK3CD,CCSER2,ZFYVE21,PURG,TATDN3,UHRF1BP1,MTMR10,REV3L,SLC25A36,FBXW7,FNIP1,CPEB3,ATF7IP,CPEB4,SOX11,MCF2L2,ITPRID2,RBFOX2,ZNF24,PMEPA1,MFF,XKR7" MicroRNA hsa-miR-578:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-09 1.19E-05 3.15E-09 2.90E-08 28 150 "TAOK1,SPAG9,DLGAP2,VCAN,SOCS5,G3BP2,FEM1B,ELAVL4,EPHB1,ACSL4,DLC1,TPPP,KCNJ10,KLHL23,LOH12CR2,TM6SF1,TMOD2,OLA1,PXK,TMEM100,GALNT10,CXXC4,MGRN1,ZMAT3,DOK6,CADM2,SLC38A1,KCNAB1" MicroRNA hsa-miR-493-3p:Functional MTI Functional MTI miRTarbase 2.15E-09 1.21E-05 3.20E-09 2.95E-08 21 88 "ARHGAP5,KIF1A,BTRC,CALM1,SRSF11,PDE4DIP,SMG7,SH3GLB1,SLC43A2,CELF1,NXPH3,ZNF678,KCNJ4,LIFR,MAP2,MXI1,PEX2,MYCBP2,SSBP2,VLDLR,CSDE1" MicroRNA hsa-miR-6757-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-09 1.21E-05 3.21E-09 2.95E-08 20 80 "ESYT2,OGT,ATP1B3,DPY19L3,C1orf52,KIAA1549L,IP6K1,HP1BP3,CPEB2,WAC,STAMBP,CELF1,SRRM4,GRIK3,STMN1,ZNF793,ZNF621,TBCEL,ZNF781,DHX33" MicroRNA hsa-miR-519d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-09 1.28E-05 3.38E-09 3.12E-08 27 141 "NCOA1,ATP1B3,CACNA1A,REPS2,SLC24A2,MYADM,FGFR1OP2,FRMPD4,RCAN1,CAB39,GFER,PTGDR2,IL6R,C2CD4C,MN1,MYO5A,NFIA,PDE1A,TMOD2,KLHL11,CYB561D1,RORB,PCMTD2,ATXN7,INKA2,SGK3,ZNF248" MicroRNA hsa-miR-4488:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-09 1.28E-05 3.39E-09 3.12E-08 23 105 "SLC12A5,BCL7A,EVI5L,CBARP,CLU,ZNF385A,CS,SPATA2,MRNIP,EIF1,TJAP1,MSI1,NEUROD2,NFIX,SMOX,FXYD1,POLR2F,SARS,SBF1,STX1A,WSCD1,NACC2,VGF" MicroRNA hsa-miR-671-3p:mirSVR_highEffct hsa-miR-671-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.29E-09 1.29E-05 3.40E-09 3.13E-08 18 65 "ASPHD1,CLK4,UPRT,CACHD1,SEC11C,GOLGA7,FGF11,NOP56,GNAO1,GRM7,LRRTM3,MTRF1L,RASGRF1,ARMC5,CUX2,TEK,MAP3K12,DOCK8" MicroRNA hsa-miR-6861-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-09 1.29E-05 3.40E-09 3.13E-08 18 65 "CC2D2A,AQP6,NIPA1,UBXN2A,FEM1B,EGR3,C8orf37,LYVE1,MPP2,TNPO2,KCNIP3,AMBRA1,MYH15,MBD5,FAM168A,TPM3,ZNF610,DHX33" MicroRNA hsa-miR-187:mirSVR_highEffct hsa-miR-187:mirSVR_conserved_highEffect-0.5 MicroRNA.org 2.30E-09 1.29E-05 3.42E-09 3.15E-08 32 190 "NDRG3,LRFN1,ARNTL,ARRB1,CCDC74A,NIPBL,CNRIP1,HIPK3,TESK2,DKK3,GAD1,GBX2,PPARGC1A,GLS,GRIA2,CLASRP,C1orf94,MAN1B1,NME9,SMAD1,MDM4,THYN1,TREM2,BDNF-AS,RAB5B,SLC6A1,NAXD,WDTC1,RBM26,FAM168A,TJP1,RICTOR" MicroRNA hsa-miR-1281:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-09 1.31E-05 3.46E-09 3.19E-08 31 180 "ATP1A2,PLAA,IGLON5,ZBTB24,TUBD1,SLC43A2,FGFR1,PCYOX1,NCKAP1,CRCP,CNDP1,GRM1,KIF3A,HMGB1,ZNF655,FAM216A,STRN3,EXOSC10,APTX,PTAFR,ZSCAN2,ZNF844,NWD1,PRRT2,CLUAP1,INKA2,DIP2A,AGTPBP1,ACSL6,SSBP2,DPYSL5" MicroRNA hsa-miR-574-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.36E-09 1.32E-05 3.50E-09 3.22E-08 12 27 "USP31,CLTC,IGLON5,EGFR,CPLX2,MUM1,C2orf72,KCNK10,RXRA,PDZD2,LHFPL4,TMEM178B" MicroRNA hsa-miR-514b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.41E-09 1.35E-05 3.57E-09 3.29E-08 24 114 "SDE2,PHF12,PROM1,ZBED1,CHRNB2,KIAA1549L,FEM1B,ELAVL2,PLEKHA1,ELAVL4,RGS17,COQ7,MSANTD4,TNRC6A,PTGDR2,CCSER2,MAGEL2,PEX26,SLC6A8,VWCE,TMPO,RIMBP2,TBC1D15,WRN" MicroRNA hsa-miR-1202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-09 1.36E-05 3.60E-09 3.32E-08 17 58 "ADD3,SFMBT2,NOL4,LDLRAD4,CBS,TMEM184B,BAG4,CTNND1,KBTBD11,KIAA1958,PIK3R1,ZBTB43,MEAF6,ZNF28,LAMP5,CSDE1,PAK5" MicroRNA hsa-miR-34b-5p:Functional MTI Functional MTI miRTarbase 2.44E-09 1.37E-05 3.62E-09 3.33E-08 25 123 "AXIN2,PNMA8B,SHROOM2,ZNF582,BTRC,EVI5L,UBXN2A,EBI3,VTI1B,TMEM151A,NEURL4,GABRB1,MALT1,FERMT2,ZNF546,KCNJ11,MAP4,MYCN,CNOT4,POLR2F,ATXN1,TROVE2,ZSCAN29,CAMSAP2,ZNF708" MicroRNA hsa-miR-6893-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-09 1.42E-05 3.74E-09 3.44E-08 22 97 "SFMBT2,SEMA4G,GPR146,DST,CACNA1A,CANX,CDC27,RAB3C,BAG4,WDPCP,IRAK4,AFF2,SRCAP,KIAA1958,KCNN1,KCTD15,HMGCLL1,CYB561D1,SCN7A,PEAR1,NFASC,DHX33" MicroRNA hsa-miR-1303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.54E-09 1.43E-05 3.77E-09 3.47E-08 33 201 "TAOK1,API5,IGDCC4,AKAP6,TBPL1,CPS1,HINFP,RUBCN,GNE,WDPCP,NEU3,ZNF276,GRIK2,PLD5,USP54,IL6ST,LAYN,MYO5A,NUCB1,FAT3,DEF8,ZNF793,ZYG11B,FBXW7,SLC30A10,ZFP30,FNDC3A,FHOD3,ATF7IP,SON,ZNF384,ZNF708,MSRB3" MicroRNA hsa-miR-449a:Functional MTI Functional MTI miRTarbase 2.61E-09 1.46E-05 3.86E-09 3.56E-08 29 161 "PKP4,PDXK,ZMYM4,EVI5L,FOXN3,CREB5,PHF19,CTIF,MRNIP,APOPT1,POLL,FICD,DDX19B,MAP4,MDM4,MKLN1,MYCN,NEUROD2,CNOT4,COPZ1,CPEB3,PEG10,SATB2,TPCN2,SLC35G2,SIRT1,TSN,SSBP2,BCL2L13" MicroRNA hsa-miR-518a-5p:Functional MTI Functional MTI miRTarbase 2.61E-09 1.46E-05 3.86E-09 3.56E-08 29 161 "GAS7,KIAA0513,EPHB1,ACSL4,TNRC6A,PRRC2B,PRUNE2,DIPK1C,MAPT,KITLG,CCDC80,PIK3C2A,KCTD15,PLEC,CRLS1,RAVER2,FOXRED2,PEX26,ATF7IP,UNC5D,ATMIN,ZMAT3,NACC2,TRPC3,TUBB2A,ZBTB38,SLC30A4,ZXDA,HNRNPA3" MicroRNA hsa-miR-205-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-09 1.50E-05 3.96E-09 3.65E-08 27 142 "SORCS2,GPAM,BCL7A,MAP7,EXOG,SH3GLB1,RCAN2,IGSF6,KATNAL1,CACNG2,PDLIM5,NPTN,GABRA2,SRRM4,TNRC6A,LUZP2,CREG2,SESN3,CNNM2,BDNF-AS,FAM19A1,ATF7IP,TET1,TROVE2,SYT11,KCTD2,ZNF45" MicroRNA hsa-miR-1203:mirSVR_highEffct hsa-miR-1203:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.73E-09 1.53E-05 4.04E-09 3.72E-08 20 81 "KCNH8,CASKIN1,TAOK1,USP3,DMTF1,TNK2,TOMM40L,NELFCD,GLI2,CLASRP,STK32C,SEPT4,SIDT1,YY1AP1,SYNDIG1,PAAF1,ADHFE1,SYNE2,TBX15,SPIRE1" MicroRNA hsa-miR-6811-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.77E-09 1.56E-05 4.10E-09 3.78E-08 23 106 "BSN,CANX,TMEM184B,ZNF385A,UBXN2A,PITPNC1,SNX29,ADAM28,GJB1,RABL2A,HAS2,TNFAIP8L3,RBPJ,GPR155,MEIS1,ZDHHC14,RUFY2,NFASC,GPRIN3,ZNF708,ZNF17,XKR7,HNRNPA3" MicroRNA hsa-miR-1270:Functional MTI Functional MTI miRTarbase 2.77E-09 1.56E-05 4.10E-09 3.78E-08 23 106 "FZD9,TEX22,SLC24A4,PDE4DIP,UBXN2A,TMEM170A,DYRK1A,FARSB,TUBD1,FAM184B,PRRC2B,CNDP1,BACH2,SHISA6,C10orf105,NEUROD1,OLA1,FAT3,RAB5B,AHCYL2,SIK3,TUBB2A,ITM2C" MicroRNA hsa-miR-585:mirSVR_highEffct hsa-miR-585:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-09 1.68E-05 4.43E-09 4.08E-08 18 66 "ARID1A,CDC25B,RUSC2,SNAP91,STAU2,ZNF512,TTBK1,KCNMA1,MAT2A,MITF,SLCO1C1,PBX1,CEP41,RAVER2,FBXO11,NUDT10,DNMBP,PUM2" MicroRNA hsa-miR-3622a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-09 1.68E-05 4.43E-09 4.08E-08 18 66 "SDE2,APAF1,FMNL3,CLOCK,ZBED3,GABRB1,TXNL4A,NR3C1,NCAM2,NOS1,TMEM104,ATAT1,SLC8A1,SS18,TBX15,RPL7L1,NSD2,WRN" MicroRNA hsa-miR-1260a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-09 1.70E-05 4.47E-09 4.12E-08 29 162 "RNF150,MTA3,OSBPL1A,AMER3,BACH1,CACNA1A,GAPVD1,RIPOR2,TOMM20,IP6K1,ABI2,SORBS3,ELAVL3,TNK2,MRPL37,GABRB1,KIF3A,MN1,CD200,PSAT1,CNNM2,GSTCD,SPIN3,STUM,KIF21A,KANSL3,ZCCHC24,CLUAP1,GAN" MicroRNA hsa-miR-652-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-09 1.70E-05 4.47E-09 4.12E-08 29 162 "MTA3,PHF12,KIF1A,DOCK11,CARS,CBS,KMT2C,QKI,CNN3,POM121,SLC12A6,TUBA1B,AGAP3,TMEM107,TNRC6A,KDM2B,EML4,HMGB1,CHST6,UHRF1BP1,MRAS,ATF7IP,RAP1GAP2,ZEB1,GPR161,EIF4ENIF1,LAT2,GDPD5,GAN" MicroRNA hsa-miR-99a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-09 1.73E-05 4.54E-09 4.18E-08 13 33 "GRAMD1B,CLTC,PUM1,KIAA0319,ABI2,GSTM5,MAP4,MMP16,ZNF621,AGTPBP1,CCDC14,WIPF1,WIPF2" MicroRNA hsa-miR-4324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-09 1.73E-05 4.55E-09 4.19E-08 30 172 "PLEKHG5,ELFN2,RNF157,MIER1,ASTN1,BACH1,CDC25B,TMEM184B,ZNF385A,CPS1,MICAL2,NCKAP1,SIGLEC8,ZNF638,HMGB1,ZDHHC15,SLC35G1,METTL21A,CHIC1,P2RX7,ZNF426,COPZ1,PEX26,TMEM136,ZNF106,RPL7L1,ZNF177,TMEM198,STOX2,LMAN2L" MicroRNA hsa-miR-6088:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-09 1.73E-05 4.55E-09 4.19E-08 30 172 "ABAT,SLC25A25,MTA3,CDC25B,BTF3L4,DBT,JAKMIP2,PLEKHA1,C1orf61,NCKAP1,FAXC,GLUL,PRRC2B,KAT7,MIER3,KCNJ3,CREG2,NOS1,NUCB1,ZNF426,PPP2R5E,ELP2,SCN2B,ELMOD1,FAM102A,NUBPL,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-4770:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-09 1.73E-05 4.55E-09 4.19E-08 30 172 "ABAT,SLC25A25,MTA3,CDC25B,BTF3L4,DBT,JAKMIP2,PLEKHA1,C1orf61,NCKAP1,FAXC,GLUL,PRRC2B,KAT7,MIER3,KCNJ3,CREG2,NOS1,NUCB1,ZNF426,PPP2R5E,ELP2,SCN2B,ELMOD1,FAM102A,NUBPL,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-6837-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-09 1.74E-05 4.57E-09 4.21E-08 22 98 "KCTD16,TAOK1,PHF12,GAS7,DGKD,STOML1,CLTA,PNKD,SUSD5,DOCK4,CENPL,NR1D2,STARD3NL,SRARP,CELF1,SYTL4,SCN8A,ZC3H13,SATB2,CYB561A3,ZNF138,ZNF195" MicroRNA hsa-miR-105-5p:Functional MTI Functional MTI miRTarbase 3.36E-09 1.89E-05 4.96E-09 4.57E-08 23 107 "ZBTB10,NCOA1,KIAA1549L,BTF3L4,CREB5,DCC,BLOC1S6,ANKRD46,ABI2,PLXNC1,RAB9B,ZIC4,COPS8,NPTX1,PDGFRA,EPB41L4B,PEG10,TJP1,TUBB2A,TOM1L2,ZNF225,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-4517:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-09 1.89E-05 4.96E-09 4.57E-08 23 107 "ABCF1,ADD2,OSBPL3,YTHDC1,MTX3,RASGRP1,KLHL5,FRY,RBM12,SCML2,FICD,BACH2,ARHGAP12,MKLN1,OLA1,CLIP1,CSMD1,TUBB2A,USP1,ZNF28,ZBTB38,ZFAND5,SLC38A1" MicroRNA hsa-miR-6511b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-09 1.89E-05 4.96E-09 4.57E-08 23 107 "BSN,CANX,TMEM184B,ZNF385A,UBXN2A,PITPNC1,SNX29,ADAM28,GJB1,RABL2A,HAS2,TNFAIP8L3,RBPJ,GPR155,MEIS1,ZDHHC14,RUFY2,NFASC,GPRIN3,ZNF708,ZNF17,XKR7,HNRNPA3" MicroRNA hsa-miR-4525:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.36E-09 1.89E-05 4.96E-09 4.57E-08 28 153 "TAOK1,ANK1,ARHGDIA,CAMK2A,METTL6,DLGAP3,TMEM184B,PLEKHM1,EFNA3,ANKRD13B,PRRC2B,KCNH2,CHST6,MPP2,NFIX,PKM,SPATA6,PTPA,DIRAS2,NCR3LG1,MYH14,SARS,PKNOX2,FNBP1,RAP1GAP2,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-2277:mirSVR_highEffct hsa-miR-2277:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.46E-09 1.94E-05 5.11E-09 4.70E-08 25 125 "ANK2,CFLAR,BRSK2,GREB1,NRSN1,EDRF1,SMG7,DPP6,RCAN1,DNM1L,WDPCP,PAN3,ARFGAP2,GUCY1A2,HSD17B1,IDNK,PAK3,PPP3CB,CDK5RAP2,MTCL1,FBXW11,SLC44A1,NPL,C9orf85,SNX14" MicroRNA hsa-miR-5696:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.50E-09 1.97E-05 5.16E-09 4.75E-08 29 163 "BRAP,KIAA1211,APP,CDK13,CALM1,APPL1,TENM1,EN2,EPHB1,FUT9,KIAA1841,GPR26,ADAMTS8,INSYN1,KCNK2,KCTD15,MAGEL2,PKIA,MDGA2,RNASEL,TMLHE,CCDC25,ACER3,ZNF331,TRAPPC13,CSRNP3,TROVE2,ZFP37,NAV2" MicroRNA hsa-miR-551b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.68E-09 2.07E-05 5.42E-09 4.99E-08 27 144 "HFM1,APP,ASPA,ZBTB10,ZMYM4,BTF3L4,DGKB,MYEF2,MTX3,RGS17,C8orf37,ZNF391,LYVE1,EML4,ARHGAP12,MITF,OPHN1,PPM1B,AMER2,FNDC3A,SON,EPB41L3,DIP2A,BHLHB9,ZNF711,EVI5,CERS6" MicroRNA hsa-miR-483-3p.1:TargetScan hsa-miR-483-3p.1 TargetScan 3.79E-09 2.13E-05 5.58E-09 5.14E-08 22 99 "CNIH2,MTMR3,GPC2,FRMPD4,DBN1,RCAN2,GAP43,MDM4,AFF1,NRGN,POLR2F,ROBO2,RPE,ATXN1,MYO18A,PEG10,IQSEC2,EXOC7,CDK20,FRRS1L,PMEPA1,HNRNPA3" MicroRNA hsa-miR-760:Functional MTI Functional MTI miRTarbase 3.91E-09 2.20E-05 5.76E-09 5.30E-08 32 194 "PDXK,CCAR2,ATP1B3,MAGED1,AKAP12,PUM1,PDCD6IP,GOLGA7,SRRM1,RTN3,TUBA1B,TOMM40L,FDFT1,ANKFY1,TUBA1C,TPPP,ATXN2L,HSP90AA1,KPNA5,NPTX1,SMOX,WBP1L,RAB5B,SGSM1,SLC8A1,SON,FBXL16,TRPS1,UBTF,PMEPA1,WNK2,UBE3B" MicroRNA hsa-miR-5010-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-09 2.20E-05 5.76E-09 5.31E-08 28 154 "TAOK1,ANK1,ARHGDIA,CAMK2A,METTL6,DLGAP3,TMEM184B,PLEKHM1,EFNA3,ANKRD13B,PRRC2B,KCNH2,CHST6,MPP2,NFIX,PKM,SPATA6,PTPA,DIRAS2,NCR3LG1,MYH14,SARS,PKNOX2,FNBP1,RAP1GAP2,UBTF,CLIP2,RICTOR" MicroRNA hsa-miR-1234:PITA hsa-miR-1234:PITA_TOP PITA 3.93E-09 2.21E-05 5.79E-09 5.33E-08 12 28 "EVI5L,APH1A,ELAVL3,LOXL3,LMO1,MSI1,SCN8A,SH3GL2,NCDN,ZC3H4,SLC30A3,SEMA3B" MicroRNA hsa-miR-4696:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.94E-09 2.21E-05 5.80E-09 5.34E-08 26 135 "MIER1,ARSE,CALM1,DLGAP3,PUM1,TMEM170A,DCC,SEC23B,TRMO,CRCP,GPR75,KCNB1,CHST6,NPTX1,SLC11A2,NDUFS7,PLEKHB2,KLHDC8A,PEX26,MPRIP,SATB2,CRTC1,TPM4,SSBP2,TBC1D15,C12orf4" MicroRNA hsa-miR-193b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.97E-09 2.23E-05 5.85E-09 5.39E-08 34 215 "ADD1,TAOK1,TRMT9B,C6orf89,API5,BMP7,CACNG1,DIS3L,AKAP6,COL9A2,SOCS5,KIAA0586,GNE,WDPCP,PDLIM5,TNRC6A,POLL,ZNF491,RBPJ,STMN1,GPR155,PAK3,SDK2,GDPD1,ZNF793,C12orf49,PTGR2,PUM2,ZNF384,ZNF708,ZNF24,ZNF138,MSRB3,GAN" MicroRNA hsa-miR-3665:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.08E-09 2.29E-05 6.00E-09 5.53E-08 30 174 "CASKIN1,FOXK1,CAMK2A,MYOM2,USP6NL,TOMM20,PITPNC1,DPYSL2,ENPP6,PTK2B,FGFR1,GNAS,CECR2,SLC2A6,TNFAIP8L3,SHISA6,GPR155,MATN3,NRGN,FXYD1,FAT3,POLR2F,SEPHS1,MAPKBP1,ZFR2,GPRIN3,KCTD2,TPM2,DPYSL5,XKR7" MicroRNA hsa-miR-3123:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.11E-09 2.31E-05 6.05E-09 5.57E-08 25 126 "BCAS1,IGDCC4,CALM1,BAG4,TM9SF4,BLOC1S6,RASA4,AMOTL2,SLC37A3,ST6GALNAC3,CRCP,COPS8,TNRC6A,GRIK2,PLD5,ZC3H12B,ZIK1,NWD1,TBCEL,AKNA,AHCYL2,NR2E1,SPIRE1,PARP11,FRMD6" MicroRNA hsa-miR-4439:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.13E-09 2.32E-05 6.07E-09 5.59E-08 21 91 "ELFN2,FEZ2,KIAA0040,DBN1,MTX3,MRNIP,FGF1,DDR2,PDE4D,KCTD15,ST8SIA5,FAM126B,ZNF621,SMOC1,MPRIP,SULF2,ZNF106,DAAM2,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-3136-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.13E-09 2.32E-05 6.07E-09 5.59E-08 21 91 "ELFN2,FEZ2,KIAA0040,DBN1,MTX3,MRNIP,FGF1,DDR2,PDE4D,KCTD15,ST8SIA5,FAM126B,ZNF621,SMOC1,MPRIP,SULF2,ZNF106,DAAM2,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-1224-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.13E-09 2.32E-05 6.07E-09 5.59E-08 21 91 "APBB2,ZBTB10,CACNA1B,GAPVD1,ABI2,SCML2,SYNCRIP,ANKFY1,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,SLIT1,NMNAT2,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-449b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-09 2.34E-05 6.12E-09 5.64E-08 24 117 "ADAR,BCL2L2,CRY2,OSBPL3,HEPH,DLG4,ANKMY1,SPECC1,STAG2,SRRM4,GPER1,MFSD2A,MSL1,IL6ST,KANSL1,PTCH1,LGR4,WDR37,INKA2,SYT5,TMEM151B,CBX5,RBFOX2,UBE2H" MicroRNA hsa-miR-6830-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-09 2.39E-05 6.25E-09 5.75E-08 19 75 "ARID1A,SLC24A4,FOXK1,IGDCC3,PLXNA4,ZNF391,NEU3,RAPGEF1,ZNF496,ITPKB,MITF,SESN3,PTPRB,TMEM231,AMER2,TMCC1,AGTPBP1,SLC44A1,CLDND1" MicroRNA hsa-miR-2114-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.25E-09 2.39E-05 6.25E-09 5.75E-08 19 75 "HECW2,LONRF2,SPATA2,C2CD2L,TMCC2,FAM135B,MTSS1L,FABP7,CELF1,TDRKH,KAT7,HAS2,NEGR1,PLD5,NCR3LG1,ATXN2,PKNOX2,PEG10,WNK1" MicroRNA hsa-miR-4680-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-09 2.42E-05 6.32E-09 5.82E-08 27 145 "ADCY2,CACNB2,C2CD2,TACC2,RNF165,ATCAY,KCNN3,CREG2,EFHB,TBC1D25,PDPK1,TMOD2,CCSER2,PPP2R5C,PIGG,NCR3LG1,ZIK1,HSPA4L,NUBPL,PEX26,ANKRD36,SSTR2,STAC2,KLHL7,SLC19A3,ZNF708,GAN" MicroRNA hsa-miR-891a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.55E-09 2.55E-05 6.67E-09 6.15E-08 28 155 "CLK4,ARID1A,XKR4,ARHGDIA,LDHD,SYNJ2,CFAP410,ENTPD4,AMOTL2,SEC23B,PARD3B,IBA57,ZNF678,GPR155,MYCN,OGDH,A2ML1,GPSM2,APTX,PLEKHB2,PEX26,ANKRD36,KLHL7,ALG1,WWC1,ZNF34,THRA,MEAF6" MicroRNA hsa-miR-6765-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.63E-09 2.60E-05 6.80E-09 6.27E-08 26 136 "SLC2A11,BACH1,CCNT1,MYOM2,CCPG1,SEC14L5,DNAH9,EIF4G1,MRNIP,COQ7,MRPL10,CEP78,MSANTD4,ZNF274,CPLX2,RBPJ,MMP17,SFR1,PIK3CD,MAPK9,ZCCHC24,CLUAP1,ZBTB43,NEK4,ZNF708,URM1" MicroRNA hsa-miR-1262:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-09 2.62E-05 6.85E-09 6.31E-08 29 165 "TXNDC16,TAOK1,CDC14B,ZNF555,COL9A2,SOCS5,SIRPA,MTX3,EIF5,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,IL17RB,UNC5B,MCF2L2,SSTR2,C3orf70,NACC2,SSBP2,USP1,SF1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-5197-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-09 2.62E-05 6.85E-09 6.31E-08 29 165 "SDE2,SLC24A4,TXNDC16,ASPA,TOMM20,DBT,PLEKHA1,POLR1B,SUCO,GPR75,KDM2B,LILRA2,IL1RAPL1,HLF,IL6R,MBNL1,AFF1,NPTX2,POU3F2,PIGG,TMEM145,NWD1,MCMBP,AMER2,LRRC55,PEG10,SSTR2,SLC35G2,VLDLR" MicroRNA hsa-miR-1296:PITA hsa-miR-1296:PITA_TOP PITA 4.68E-09 2.63E-05 6.86E-09 6.32E-08 14 40 "PTCHD1,INTS2,ADGRB1,CAMK2G,ZNF521,DCAF8,TESK2,TMEM255A,SLC6A15,SFPQ,SYN1,WASHC4,CADM1,CSDE1" MicroRNA hsa-miR-3201:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.68E-09 2.63E-05 6.86E-09 6.32E-08 14 40 "CA8,CDC25B,CLCN3,ELAVL2,CELF1,KCNMB4,GRIK2,BACH2,PRRX1,PTPRD,CEP97,MBD5,PCDHA6,PARD3" MicroRNA hsa-miR-1298:PITA hsa-miR-1298:PITA_TOP PITA 4.74E-09 2.66E-05 6.95E-09 6.40E-08 13 34 "ATP2B2,BMP7,BAG4,SRGAP3,PDCD6IP,DNER,TTBK1,LRRTM3,MXI1,NCAM1,ARID4A,YPEL4,TRPS1" MicroRNA hsa-miR-5571-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.07E-09 2.85E-05 7.42E-09 6.84E-08 34 217 "SDE2,AS3MT,ZNF578,PARG,GPAM,KIAA1614,ATP1B3,ALDH7A1,CAMK2G,CLOCK,HINFP,MRNIP,CRCP,HNRNPK,KCNK2,KPNA5,L1CAM,NCOA7,AFF1,FAM216A,SPATA6,ZNF844,PGBD4,SGK1,PEX26,TET1,ZFP1,SMARCE1,ZNF415,ASTN2,PCDHA6,DDHD1,REEP1,ZNF195" MicroRNA hsa-miR-5583-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.09E-09 2.86E-05 7.46E-09 6.87E-08 21 92 "ABCF1,ADD2,BRAP,BBOX1,CCNT1,CDC27,DNAL1,YTHDC1,RASGRP1,KLHL5,MBNL2,BACH2,MBNL1,MKLN1,OLA1,PTPRD,ARL10,CSMD1,ZNF28,ZBTB38,SLC38A1" MicroRNA hsa-miR-379-5p:TargetScan hsa-miR-379-5p TargetScan 5.09E-09 2.86E-05 7.46E-09 6.87E-08 21 92 "HECW2,ARRB1,MTMR2,PITPNM3,JAKMIP2,EDN1,EIF4G2,KATNAL1,PCDH17,RAB30,CACFD1,FICD,KNDC1,KCTD6,HCN1,FIGN,CYB561D1,KIAA0895L,PEG10,LGI4,MRPL47" MicroRNA hsa-miR-6738-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-09 3.02E-05 7.88E-09 7.26E-08 20 84 "WDR35,SLC7A14,DLGAP2,TOGARAM2,CPS1,BOC,DCAF8,TMEM170A,DCC,YTHDC1,EDN1,EPB41,GPR45,PPM1L,MDGA1,NEUROD1,RFX3,ASTN2,SF1,AGMO" MicroRNA hsa-miR-1295b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-09 3.02E-05 7.88E-09 7.26E-08 20 84 "KIAA1614,DGKG,FKTN,ZBED3,NEU3,GCK,CTNNA3,XRN1,TMEM38A,FAT3,RAB5B,RBBP6,CSRNP3,IGSF9B,EMC1,MAPK8IP3,CAMSAP2,DOCK9,WRN,CADM2" MicroRNA hsa-miR-379-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-09 3.02E-05 7.88E-09 7.26E-08 20 84 "CCDC74A,ATP1B3,JAZF1,ATRNL1,FSD1L,TUBD1,SCML2,MMADHC,C5orf24,SH3TC2,ALG9,PGBD4,FBXW7,FNIP1,SYPL1,TJP1,FAM182B,ACTR3B,FXR1,NETO2" MicroRNA hsa-miR-4778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.40E-09 3.03E-05 7.90E-09 7.28E-08 19 76 "GRAMD1B,BTF3L4,CPS1,SOCS5,JAKMIP2,RAB39B,GABRA1,IL6ST,LSAMP,NCAM2,GTDC1,TMEM100,CSRNP3,TET1,EPC1,ZHX3,EMC1,ZBTB38,CADM2" MicroRNA hsa-miR-134-5p:Functional MTI Functional MTI miRTarbase 5.63E-09 3.16E-05 8.23E-09 7.58E-08 22 101 "FMNL2,ELFN2,USP37,CA12,KIAA0040,MAGI2,RCAN1,MRNIP,ERBB2,FOXM1,TRMO,TJAP1,IL6ST,POLR2F,PEX26,FAM126B,ZNF621,SMOC1,PUM2,ZNF106,KAT6B,UPF3A" MicroRNA hsa-miR-7853-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.63E-09 3.16E-05 8.23E-09 7.58E-08 22 101 "ZBTB10,NCOA1,KIAA1549L,BTF3L4,CREB5,DCC,BLOC1S6,ANKRD46,ABI2,PLXNC1,RAB9B,ZIC4,COPS8,NPTX1,PDGFRA,EPB41L4B,PEG10,TUBB2A,TOM1L2,ZNF225,CIAPIN1,HNRNPA3" MicroRNA hsa-miR-595:Functional MTI Functional MTI miRTarbase 5.63E-09 3.16E-05 8.23E-09 7.58E-08 22 101 "ELFN2,PCDH10,MTMR3,CALM1,ENTPD4,KLHL3,PARD6A,WAC,ATP13A4,C15orf41,FICD,HMGB1,BLOC1S2,PFKP,ST8SIA5,SLC25A23,PGBD4,ATXN1,URGCP,MPRIP,ZFP91,TMPO" MicroRNA "TCTGATC,MIR-383:MSigDB" "TCTGATC,MIR-383:MSigDB" MSigDB 5.69E-09 3.20E-05 8.32E-09 7.66E-08 15 47 "SORCS1,DCLK1,FOXN3,BLOC1S6,TAOK3,GABRB3,PCDH17,SLC2A6,NEUROD1,MAPKAP1,STRN3,NXPH1,SHMT2,SOX5,IDI2-AS1" MicroRNA "CCACACA,MIR-147:MSigDB" "CCACACA,MIR-147:MSigDB" MSigDB 5.70E-09 3.20E-05 8.33E-09 7.67E-08 17 61 "ACLY,ANK1,ATP1A1,CREB5,DLG4,AHCYL1,GRID1,NR3C1,MYLK2,ZNF827,PCMT1,PDPK1,PLP1,RGS3,ROBO2,CAMTA1,SLC44A1" MicroRNA hsa-miR-3120-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.76E-09 3.24E-05 8.42E-09 7.76E-08 25 128 "APP,MYRF,HS3ST5,RBM12,STARD3NL,DKK3,DHX35,METTL21A,LIFR,SHC3,GPR137C,PDE4D,PRKACB,TRERF1,MPRIP,SYP,DNMBP,TMEM136,CRTC1,ASXL3,TUBB2A,RPL7L1,TBC1D15,NDRG4,SLC30A4" MicroRNA hsa-miR-1264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-09 3.32E-05 8.62E-09 7.94E-08 23 110 "KIAA1211,SEMA7A,TNRC6C,ZNF555,QKI,EDIL3,RGS17,DCTN4,POLR1B,IP6K2,ZBED3,GATM,KLF12,CHIC1,MYO6,PCDH9,PDE1A,RFX3,EXD2,ANKRD6,SMOC1,HEY2,FXR1" MicroRNA hsa-miR-2682-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.90E-09 3.32E-05 8.62E-09 7.94E-08 23 110 "PNMA8B,SHROOM2,ZNF582,BTRC,EVI5L,UBXN2A,EBI3,VTI1B,TMEM151A,NEURL4,GABRB1,MALT1,FERMT2,ZNF546,KCNJ11,MAP4,CNOT4,POLR2F,ATXN1,TROVE2,ZSCAN29,CAMSAP2,ZNF708" MicroRNA hsa-miR-1295:mirSVR_highEffct hsa-miR-1295:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.99E-09 3.36E-05 8.73E-09 8.04E-08 16 54 "ABHD6,PPFIA1,ZNF583,CBS,RAB28,EGR3,GAP43,MATN2,MBD1,MTR,EPB41L4B,RBBP6,LRFN5,FHOD3,TRO,WNK1" MicroRNA hsa-miR-617:Non-Functional MTI Non-Functional MTI miRTarbase 5.99E-09 3.36E-05 8.73E-09 8.04E-08 16 54 "TMEM132B,HECW2,CCPG1,MRPL37,GRIK3,INSYN1,KCNJ10,THYN1,NTRK3,PBX1,MYH15,LIMCH1,NECAB1,ATP11A,CBX5,URM1" MicroRNA hsa-miR-208a-3p:Functional MTI Functional MTI miRTarbase 5.99E-09 3.36E-05 8.73E-09 8.04E-08 16 54 "AXIN2,CACNB2,QKI,LIN54,DGKG,CPEB2,CELF1,IQGAP2,ARHGAP12,MAPK10,ZNF844,SOX6,ASAP3,AMBRA1,FGD4,TUBB2A" MicroRNA hsa-miR-5186:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.02E-09 3.38E-05 8.78E-09 8.08E-08 37 251 "FOXK1,CBS,CDC25B,UBXN2A,GAPVD1,KIAA0513,TOMM20,DNAL1,HP1BP3,ATP13A4,TRMO,ZNF234,DISC1,KIAA1958,LILRA2,NR3C1,MFSD2A,NKD1,DOCK7,IBA57,CHST6,BLOC1S2,CCSER2,FAT3,CNNM2,MTMR10,RBBP8,CSRNP3,EMC1,LHPP,PBLD,HHIP,BHLHB9,PPIL6,RFTN2,TUBB2A,XKR7" MicroRNA hsa-miR-586:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.27E-09 3.52E-05 9.13E-09 8.41E-08 21 93 "THSD7A,CALM1,C1orf52,RBM12,TLR7,ACSL4,FOXG1,ZBED3,MMADHC,COPS8,LILRA2,GRIK3,ZIC5,ZNF678,GPR173,PLP1,OXR1,DICER1,TNS1,RPL7L1,KCNK12" MicroRNA hsa-miR-3934-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.27E-09 3.52E-05 9.13E-09 8.41E-08 21 93 "ABCF1,TBPL1,PPP1R16B,FBXL5,ABI2,TNRC6A,POLL,ZIC5,GPR155,PPM1L,CCDC80,MYO5A,RDX,C12orf49,RMI1,CLSTN1,ANKRD36,DDN,CAMSAP2,RPL7L1,PLSCR4" MicroRNA hsa-miR-4729:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.39E-09 3.59E-05 9.31E-09 8.57E-08 26 138 "KIAA1211,KCTD16,USP28,ARHGDIA,CALM1,MYADM,DBN1,SYNCRIP,SMC2,KIAA1841,NUDT21,ADAMTS8,IL6ST,KCNK2,LIMS1,FGFBP3,KCTD15,TMLHE,ZNF331,CSRNP3,ATXN1,GPRIN3,TNS1,RBFOX2,ZFP37,ZNF138" MicroRNA hsa-miR-1250:PITA hsa-miR-1250:PITA_TOP PITA 6.39E-09 3.59E-05 9.32E-09 8.58E-08 12 29 "ATP1A1,BSN,FMNL3,CHN1,CAMSAP1,GRIN1,IL1RAPL1,ZNF827,PTPRO,SS18,REEP1,PHTF2" MicroRNA hsa-miR-501-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.52E-09 3.66E-05 9.49E-09 8.74E-08 18 69 "NLGN4X,CA12,CDC27,ELAVL2,TOMM40L,MTHFD2,SESN1,AGBL5,IBA57,MSI1,PLEKHB2,PEG10,ZBTB43,SSTR1,PLCB1,UBE2H,LINC00632,FAM219B" MicroRNA hsa-miR-541-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.71E-09 3.77E-05 9.76E-09 8.99E-08 20 85 "TAOK1,OGT,CAPRIN2,LDHD,ARHGEF7,CTNND1,ELMSAN1,G3BP2,ELAVL2,C8orf37,CELF1,DOT1L,RAPGEF1,KCNA6,ZNF426,TGFBR3,AKTIP,TUBB2A,UBE3A,PRDM2" MicroRNA hsa-miR-6769a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.83E-09 3.84E-05 9.94E-09 9.15E-08 19 77 "XKR4,TEX22,BCL2L2,LONRF2,SIRPA,REEP2,MSANTD4,OPALIN,METTL21A,STMN1,MMP17,NEXMIF,VWA2,PPP3CB,STX1B,SCN7A,SLC8A3,RPL7L1,DPYSL5" MicroRNA hsa-miR-888-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.83E-09 3.84E-05 9.94E-09 9.15E-08 19 77 "CDK13,FOXN3,CNN3,ARHGEF6,G3BP2,SLC12A6,GNE,CELSR3,ABI2,RAB9B,RNPS1,RFFL,KIF3A,SMIM11A,MAPK8,PROX1,LIMCH1,UNC80,TBC1D15" MicroRNA hsa-miR-3616-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-09 3.84E-05 9.94E-09 9.16E-08 22 102 "XKR4,ADCY5,OGT,NUMBL,CBARP,TM9SF4,PHYHIP,E2F6,CHST15,SRCAP,ARHGAP12,PPM1L,SESN3,NEUROD2,TNPO2,SLC6A9,SSTR1,PUM2,CBX5,TMPRSS5,PMEPA1,GAN" MicroRNA hsa-miR-6805-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-09 3.84E-05 9.94E-09 9.16E-08 22 102 "NDRG3,CASKIN1,EVI5L,ZNF385A,SPATA2,ABCC5,EIF1,AHDC1,RAPGEF1,MMP17,MSI1,NEUROD2,PDE4A,FXYD1,PTPA,SHMT2,SON,NMNAT2,ERC1,THRA,MGAT5B,CIAPIN1" MicroRNA hsa-miR-6748-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.06E-09 3.97E-05 1.03E-08 9.46E-08 24 120 "IGDCC4,BCL7A,DIRAS1,SLC22A6,CSNK1E,PHF19,ABI2,TNRC6A,TNFAIP8L3,MPP2,NFIX,NUCB1,RETREG2,RAB5B,CEP97,SETD5,CLIP1,SOX5,UNC5B,TPCN2,UBTF,ZNF28,SLC38A1,NAV2" MicroRNA hsa-miR-935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.06E-09 3.97E-05 1.03E-08 9.46E-08 24 120 "RNF150,ATP1B3,CANX,TBPL1,PITPNC1,SMG7,MTX3,ABCC5,ASB3,F3,FLT1,NBEA,CAB39,PKM,FITM2,NWD1,PCMTD2,TMEM200C,SLC12A2,ITPRID2,SUPT5H,LMF1,SF1,ZFP37" MicroRNA hsa-miR-527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.07E-09 3.97E-05 1.03E-08 9.46E-08 28 158 "GAS7,KIAA0513,EPHB1,ACSL4,TNRC6A,PRRC2B,PRUNE2,DIPK1C,MAPT,KITLG,CCDC80,KCTD15,PLEC,CRLS1,RAVER2,FOXRED2,PEX26,ATF7IP,UNC5D,ATMIN,ZMAT3,NACC2,TRPC3,TUBB2A,ZBTB38,SLC30A4,ZXDA,HNRNPA3" MicroRNA hsa-miR-744:PITA hsa-miR-744:PITA_TOP PITA 7.19E-09 4.04E-05 1.05E-08 9.63E-08 13 35 "CSMD2,UNC5A,ZNF385A,IP6K1,PHC2,ZIC4,GRIN2D,CAMK2N2,NFIX,ZNF827,PPP5C,TCF7,SZT2" MicroRNA hsa-miR-7851-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.40E-09 4.16E-05 1.08E-08 9.91E-08 32 199 "XKR4,TRMT9B,CDC14B,ASPA,FOXK1,MYOM2,CDR1,COL9A2,NRG2,SYT15,RASA4,IRAK4,MRNIP,TRMO,KBTBD12,DISC1,LILRA2,KAT7,DDX19B,SCRG1,IBA57,LIMS1,QDPR,PGBD4,ZCCHC24,NFASC,PRRC2C,FAM208A,CLASP1,BHLHB9,SSBP2,ZNF154" MicroRNA hsa-miR-561-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.48E-09 4.20E-05 1.09E-08 1.00E-07 17 62 "ARID1A,ADAR,BRAP,SLC24A4,FOXK1,SUMF2,IGDCC3,PLXNA4,FGFR1,SLC37A3,RAPGEF1,ITPKB,SESN3,PTPRB,TMEM231,TAL1,NR2E1" MicroRNA hsa-miR-3972:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.04E-09 4.52E-05 1.17E-08 1.08E-07 16 55 "ADD3,SFMBT2,NOL4,LDLRAD4,CBS,TMEM184B,BAG4,CTNND1,KBTBD11,KIAA1958,PIK3R1,ZBTB43,MEAF6,ZNF28,CSDE1,PAK5" MicroRNA hsa-miR-6089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.07E-09 4.53E-05 1.17E-08 1.08E-07 30 179 "SLC24A4,TXNDC16,PDZD4,TRMT9B,KIAA1614,DNAH17,HCN2,ISPD,EVI5L,GREB1,USP6NL,DNAL1,ABI2,ANKRD13B,STX2,PNMA2,GNG4,KIF3A,ZNF491,CCDC80,NFIX,NKX2-2,NUCB1,ZNF713,NLE1,RETREG2,PPARA,CEP97,KCNIP3,UHRF1BP1L" MicroRNA hsa-miR-570-3p:Functional MTI Functional MTI miRTarbase 8.07E-09 4.53E-05 1.17E-08 1.08E-07 30 179 "KLRC4,MTA3,IGDCC4,FOXK1,CANX,ISPD,BAG4,MYADM,BLOC1S6,SCML2,CELF1,SRRM4,TNRC6A,FUT10,GRB10,IL6R,KCNB1,ADAM22,NASP,SETD5,SGK1,SMTN,SLIT1,CXXC4,SOX3,CLUAP1,HHIP,DDHD1,TPM3,SLC38A1" MicroRNA hsa-miR-641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.28E-09 4.65E-05 1.20E-08 1.11E-07 22 103 "SDE2,KLHL32,AXIN2,ANK1,THSD7A,CANX,LIN54,GOLT1B,DLC1,IQGAP2,P2RY1,MAPK10,FIGN,NBPF1,ANKRD36,LIMCH1,SNAP25,POGZ,FGD4,SLC35G2,ZNF106,CLDND1" MicroRNA hsa-miR-3976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.32E-09 4.67E-05 1.21E-08 1.11E-07 20 86 "ARSE,BCL7A,CACNG1,PDE4DIP,TMEM170A,DBT,BLOC1S6,ABI2,DLC1,EFCAB2,SPECC1,ATOH8,NKAIN1,SLC6A8,SEPHS1,ANKRD36,SEPT8,AHCYL2,NR2E1,SPIRE1" MicroRNA hsa-miR-7852-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.36E-09 4.69E-05 1.21E-08 1.12E-07 18 70 "FZD9,PCDH10,CLTA,ANKRD46,GORAB,SESN1,TNRC6A,NUDT21,IL6ST,ZNF678,KIF5A,MYO5A,RDX,FIGN,PRIMA1,MCMBP,BTBD3,CADM1" MicroRNA hsa-miR-4726-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.39E-09 4.71E-05 1.22E-08 1.12E-07 32 200 "SLC12A5,PTCHD1,MTA3,GOLGA7B,DYNLL1,FOXK1,DIRAS1,TMEM184B,RTTN,RNF14,FGFR1OP2,IP6K1,CNNM1,HEYL,APH1A,MSANTD4,KIAA1958,KIF3A,BACH2,NKD1,IL6R,THYN1,FAM216A,PTPRB,ZNF844,RGS12,SHMT2,ACSL6,CYB561A3,ERCC6L2,TSPAN11,SLC38A1" MicroRNA hsa-miR-4329:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.49E-09 4.77E-05 1.23E-08 1.13E-07 23 112 "KLHL32,CC2D2A,TRMT9B,LONRF2,MICAL2,SLC43A2,MRVI1,GABRB1,SIGLEC8,HTR2A,NUCB1,GPR173,PRKAB2,CEP97,CSRNP3,SLC37A2,PRMT8,TBC1D15,ZNF45,ZNF74,ZNF177,TMEM198,PHTF2" MicroRNA hsa-miR-541:PITA hsa-miR-541:PITA_TOP PITA 8.60E-09 4.83E-05 1.25E-08 1.15E-07 19 78 "CADM3,TMEM257,KCNAB3,FOXN3,CABP1,ZNF385A,CLIP3,JPH4,TNRC6A,GRIN2D,CNOT4,PRRX1,FAM120C,SLC1A2,SMTN,SMARCE1,SMOC1,ST5,KIAA0930" MicroRNA hsa-miR-3943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.60E-09 4.83E-05 1.25E-08 1.15E-07 19 78 "TEX22,KIF6,BCL2L2,HCN2,NEURL1,KIF26A,SIRPA,NSG2,MUM1,HSP90AA1,METTL21A,STMN1,NEXMIF,NODAL,NSD1,RPL7L1,TOM1L2,GDPD5,PIANP" MicroRNA hsa-miR-4735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.21E-09 5.17E-05 1.33E-08 1.23E-07 30 180 "TMEM132B,FZD9,KIAA1614,CACNG1,PTBP2,LETMD1,NSL1,CRY2,DBT,FARSB,C8orf37,EPB41L1,WAC,SRRM4,MALT1,ZNF276,MXI1,NUCB1,GPR137C,PDE3B,FAM216A,PLCL1,FAM161B,TET1,AGTPBP1,KIAA0930,CBX5,SSBP2,LINC00632,HNRNPA3" MicroRNA hsa-miR-374c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.39E-09 5.28E-05 1.36E-08 1.25E-07 21 95 "CAPRIN2,NRP2,CANX,HIPK3,TMTC1,GPR26,DIPK1A,MID1,SESN3,SATB1,TRIM67,TROVE2,EXOC7,CAMSAP2,TRIM2,PSD3,TRPS1,ZNF610,TBC1D15,SPIRE1,ZDHHC20" MicroRNA hsa-miR-130a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.44E-09 5.30E-05 1.37E-08 1.26E-07 25 131 "ADD3,NLGN4X,ZNF578,HAPLN1,DOCK4,TMEM170A,FSD1L,EN2,CELF1,MPP6,ADAM28,TNRC6A,SNTG1,ZNF426,CRLS1,ZIK1,ACSS3,BSDC1,SEMA6D,FNIP1,ERBIN,TPM3,RPL7L1,ZNF138,JMJD1C" MicroRNA hsa-miR-3171:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.68E-09 5.44E-05 1.40E-08 1.29E-07 14 42 "ESYT2,PHF12,ATP1B3,ATP2A2,SRSF11,COL4A5,ANKRD44,SYT9,MMP16,CCDC80,PDE3A,CHD9,ZHX3,FRYL" MicroRNA hsa-miR-4314:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-08 5.62E-05 1.45E-08 1.33E-07 22 104 "AP1M1,NIPA1,COL9A2,UBXN2A,RIPOR2,IP6K1,RASA4,VPS26C,MTHFD2,CRCP,GLUL,POLL,BVES,NEGR1,ATCAY,MPP2,KCNIP3,PEX26,MBD5,AJAP1,ZBTB38,DHX33" MicroRNA hsa-miR-147b:mirSVR_highEffct hsa-miR-147b:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.00E-08 5.62E-05 1.45E-08 1.33E-07 22 104 "ADAM15,BTK,CBFA2T2,FBXL5,DTNB,AIFM3,RAPGEF4,KCNN2,BDNF-AS,RGS7,KIF7,RORB,ZFP2,SEC14L1,FAM102A,CLSTN1,SEPHS1,KIF13A,C11orf87,KAT6B,WIPF1,NDRG4" MicroRNA hsa-miR-151-5p:PITA hsa-miR-151-5p:PITA_TOP PITA 1.02E-08 5.71E-05 1.47E-08 1.35E-07 12 30 "RALGAPA1,SLC12A5,NRP2,RIMS4,ELAVL3,RGS17,AGAP3,NTRK2,ARX,IGSF9B,SNAP25,NMNAT2" MicroRNA hsa-miR-22-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-08 5.78E-05 1.49E-08 1.37E-07 20 87 "TNRC6C,C1orf52,UBXN2A,YTHDC1,SEC16A,RCAN1,GOLT1B,YAF2,ERBB2,AFF2,STAMBP,NCKAP1L,XRRA1,NCAM2,PDE3A,PNMA3,SH3TC2,RAB3GAP1,FAM208A,TNS1" MicroRNA hsa-miR-4505:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-08 5.90E-05 1.52E-08 1.40E-07 30 181 "ADAR,PNMA8B,CEP126,ARHGDIA,FOXK1,METTL6,NEURL1,CLU,RGS6,MYADM,ANKRD13B,CELF1,GRM1,IRAK3,IBA57,KCNH2,MMP17,PKM,PTPA,PEX2,RAB5B,KLHDC8A,ELP2,KIAA0895L,MAGI3,SLIT1,RAP1GAP2,MAPK8IP3,ZNF24,TMEM63C" MicroRNA hsa-miR-5590-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-08 5.99E-05 1.54E-08 1.42E-07 18 71 "SERPINA3,CD38,PITPNM3,DBN1,EBF1,WAC,BRPF3,ZNF274,GPR26,NR3C1,HSP90AA1,GDPD1,NWD1,SALL1,TRPS1,VLDLR,ZNF138,PRDM10" MicroRNA hsa-miR-634:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-08 5.99E-05 1.54E-08 1.42E-07 18 71 "SYT6,FEZ2,CSNK1E,PLEKHM1,CALN1,ABCC5,PLEKHA1,F5,FGFR1,GRIK3,FAM107A,C2orf72,KCNN1,ZNF34,WBP2,ZNF154,DHX33,ZNF248" MicroRNA hsa-miR-218-2-3p:Functional MTI Functional MTI miRTarbase 1.07E-08 5.99E-05 1.54E-08 1.42E-07 18 71 "TMEM263,CDC27,USP6NL,E2F5,DCTN4,RABEPK,STAMBP,SESN3,ZDHHC22,OLA1,ZNF655,SETD5,ROBO1,ZNF415,SON,ZC4H2,STAU1,ZNF195" MicroRNA "AAGGGAT,MIR-188:MSigDB" "AAGGGAT,MIR-188:MSigDB" MSigDB 1.07E-08 5.99E-05 1.54E-08 1.42E-07 18 71 "USP28,CHRD,CDC25B,NTM,NBEA,KLF12,MBNL1,MEF2C,KITLG,PCDH9,PDE4A,FBXW7,ATXN1,FBXO11,SLC12A2,ZFP91,NSD2,RICTOR" MicroRNA "CAGGTCC,MIR-492:MSigDB" "CAGGTCC,MIR-492:MSigDB" MSigDB 1.07E-08 6.03E-05 1.55E-08 1.43E-07 16 56 "NCOA1,DBN1,DYRK1A,RNF165,SCRT2,MAT2A,NPTX1,PFKFB2,SCN2B,TRA2B,CPEB3,AMBRA1,NCDN,CYB561A3,SLC44A1,SMARCAD1" MicroRNA hsa-miR-1245b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-08 6.06E-05 1.56E-08 1.43E-07 19 79 "ESYT2,C6orf89,FOXN3,PHF19,MATR3,DOCK7,KCNN3,SESN3,NUCB1,PDPK1,EPB41L4B,RGR,SARS,KIF21A,ZMAT3,RPL7L1,MEAF6,ZNF24,ZNF154" MicroRNA hsa-miR-4736:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-08 6.06E-05 1.56E-08 1.43E-07 29 171 "FOXK1,CAMK2A,MYOM2,LONRF2,CFL2,LETMD1,PITPNM3,USP6NL,KIAA0513,TOMM20,MRNIP,PTK2B,CELF1,FUT10,TNFAIP8L3,MATN3,SLC11A2,NRGN,PDE3A,FAT3,POLR2F,AMER2,ATXN1,STUM,PEX26,MYH15,TMCC1,ZSCAN29,DPYSL5" MicroRNA hsa-miR-208b-3p:Functional MTI Functional MTI miRTarbase 1.08E-08 6.09E-05 1.56E-08 1.44E-07 15 49 "AXIN2,CACNB2,QKI,LIN54,DGKG,CPEB2,CELF1,IQGAP2,ARHGAP12,MAPK10,ZNF844,ASAP3,AMBRA1,FGD4,TUBB2A" MicroRNA hsa-miR-1273c:mirSVR_highEffct hsa-miR-1273c:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.11E-08 6.23E-05 1.60E-08 1.47E-07 25 132 "CSMD2,DPY19L2P4,RTL9,OGT,SHTN1,BLM,CACNB2,NUMBL,CACNA2D2,OLIG1,SEMA3D,EGFR,RBPJ,LRRTM3,PDGFRA,RFX2,STK32B,MEG3,SMPD3,ST3GAL3,SMARCA4,UNC5D,CRB1,TCEAL7,RGS7BP" MicroRNA hsa-miR-23c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-08 6.23E-05 1.60E-08 1.47E-07 25 132 "ADD3,NLGN4X,ZNF578,HAPLN1,DOCK4,TMEM170A,FSD1L,EN2,CELF1,MPP6,ADAM28,TNRC6A,SNTG1,ZNF426,CRLS1,ZIK1,ACSS3,BSDC1,SEMA6D,FNIP1,ERBIN,TPM3,RPL7L1,ZNF138,JMJD1C" MicroRNA hsa-miR-5787:Functional MTI Functional MTI miRTarbase 1.20E-08 6.73E-05 1.73E-08 1.59E-07 30 182 "ADAR,PNMA8B,CEP126,ARHGDIA,FOXK1,METTL6,NEURL1,CLU,RGS6,MYADM,ANKRD13B,CELF1,GRM1,IRAK3,IBA57,KCNH2,MMP17,PKM,PTPA,PEX2,RAB5B,KLHDC8A,ELP2,KIAA0895L,MAGI3,SLIT1,RAP1GAP2,MAPK8IP3,ZNF24,TMEM63C" MicroRNA hsa-miR-941:mirSVR_highEffct hsa-miR-941:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-08 6.76E-05 1.74E-08 1.60E-07 22 105 "TAOK1,MTMR9,CACNA1G,CLCN3,CNN3,CSNK1E,NCAN,TNRC6A,TMEM25,VSIG4,MN1,SMIM11A,VPS13C,STK32A,RGS10,ZFHX4,ITSN1,RGL1,CRB1,NSD2,CASC15,IFT88" MicroRNA hsa-miR-744:mirSVR_highEffct hsa-miR-744:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.20E-08 6.76E-05 1.74E-08 1.60E-07 22 105 "PTCHD1,BIN1,STK33,LINC00906,CD86,EDNRA,PHC2,ELN,FCGRT,C1QL1,RNF165,NBL1,CDK18,PENK,NALCN,RGS3,SLC1A7,IQSEC2,ANO4,TCF7,TIE1,CADM1" MicroRNA hsa-miR-513c-5p:Functional MTI Functional MTI miRTarbase 1.21E-08 6.80E-05 1.74E-08 1.61E-07 23 114 "SDE2,PHF12,PROM1,ZBED1,KIAA1549L,FEM1B,ELAVL2,PLEKHA1,ELAVL4,RGS17,COQ7,MSANTD4,TNRC6A,PTGDR2,CCSER2,MAGEL2,PEX26,SLC6A8,VWCE,TMPO,RIMBP2,TBC1D15,WRN" MicroRNA hsa-miR-6801-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-08 6.80E-05 1.74E-08 1.61E-07 23 114 "SLC24A4,TRMT9B,KIF6,ARHGDIA,EPS15L1,TMEM184B,HAPLN1,TMEM170A,TUBB4A,ANKFY1,HHIPL1,KPNA5,SESN3,NLE1,SH3TC2,C12orf49,MYO18A,NUBPL,ZNF621,FAM168A,TPM3,SGK3,MEAF6" MicroRNA hsa-miR-6847-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-08 6.94E-05 1.78E-08 1.64E-07 27 152 "PLEKHH1,ARHGDIA,NIPA1,CCPG1,ZFYVE9,AKAP5,PITPNM3,GREB1,DNAL1,SPECC1,CELF1,TRAF3IP2,GNAS,MUM1,IGF1,KCNJ5,OPHN1,PEX2,SH3BP2,CNKSR2,INAVA,RPL7L1,ZNF711,ZNF17,SLC38A1,FBXO36,NUP214" MicroRNA hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA_TOP PITA 1.35E-08 7.57E-05 1.94E-08 1.79E-07 19 80 "CADM3,TMEM257,KCNAB3,FOXN3,CABP1,ZNF385A,CLIP3,JPH4,TNRC6A,GRIN2D,CNOT4,PRRX1,FAM120C,SLC1A2,SMTN,SMARCE1,SMOC1,ST5,KIAA0930" MicroRNA hsa-miR-3660:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-08 7.61E-05 1.95E-08 1.80E-07 18 72 "SLC25A25,INTS2,TRIM41,CCNT1,PPP1R16B,PLEKHM1,RPS6KL1,AMOTL2,B4GALNT1,SESN1,LSAMP,CHIC1,NODAL,GPSM2,PRKACB,TMEM200C,TMEM151B,UPF3A" MicroRNA hsa-miR-6885-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-08 7.78E-05 1.99E-08 1.83E-07 26 143 "AS3MT,ADCY6,PWWP2A,MTUS1,PCDH19,ARSE,NCOA1,PTBP2,LETMD1,KLHL5,CDHR1,HBS1L,NTNG2,CD200,NCAM2,NPTX1,PDGFRA,ZSCAN2,ROBO1,ATXN1,NTNG1,LRRC55,SEPHS1,ANKRD28,CADM1,UBE2H" MicroRNA hsa-miR-2278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-08 7.80E-05 2.00E-08 1.84E-07 24 124 "AXIN2,GRAMD1B,FZD9,DNAH17,ZBTB10,FMNL3,ARHGAP32,EFNA3,DLC1,ATP8A2,ATOH8,SHISA6,MSL1,MN1,OGDH,PAK3,PACSIN1,RNH1,EPN2,ANKRD36,AJAP1,TPM3,UBE2H,WIPF2" MicroRNA hsa-miR-4691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-08 7.80E-05 2.00E-08 1.84E-07 24 124 "SDE2,SORCS2,PCDHGB4,SLC2A11,BCL2L2,CTNND1,TMTC1,MRO,ANKMY1,GABRB3,LYVE1,GLYR1,MFSD2A,PTCH1,TTC13,RDX,HUNK,ZFP30,YPEL4,DIP2A,SYT5,TMEFF2,UBE2H,ZNF711" MicroRNA hsa-miR-6883-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.42E-08 7.99E-05 2.04E-08 1.88E-07 16 57 "AK2,LDHD,CACNA1G,RCAN1,CELSR3,PLEKHA1,WASF3,NUDT21,KCNJ10,NFIA,DDR2,BCAS3,ZNF793,ATXN1,NECAB1,AP3B2" MicroRNA hsa-miR-6736-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-08 8.07E-05 2.06E-08 1.90E-07 28 163 "TXNDC16,TAOK1,CDC14B,ZNF555,COL9A2,SOCS5,SIRPA,MTX3,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,IL17RB,UNC5B,MCF2L2,SSTR2,C3orf70,NACC2,SSBP2,USP1,SF1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-4701-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-08 8.07E-05 2.06E-08 1.90E-07 28 163 "TXNDC16,TAOK1,CDC14B,ZNF555,COL9A2,SOCS5,SIRPA,MTX3,RNPS1,RNF165,KIT,RETREG2,PPP2R5E,STK32A,PRRT2,KCNIP3,IL17RB,UNC5B,MCF2L2,SSTR2,C3orf70,NACC2,SSBP2,USP1,SF1,ZNF28,SLC30A4,GAN" MicroRNA hsa-miR-564:mirSVR_highEffct hsa-miR-564:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.44E-08 8.10E-05 2.07E-08 1.91E-07 23 115 "EP400,LGR5,PHC2,NOP56,NEK6,CLASRP,LINC01102,MAOB,NRGN,STRN3,TMEM260,RGS10,RIC8B,EPB41L3,CAMTA1,CUX2,PCDHA2,SIK3,ZIC2,ZIC3,ZSCAN26,SLC17A7,TMEM63C" MicroRNA hsa-miR-580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-08 8.75E-05 2.24E-08 2.06E-07 20 89 "TAOK1,LRCH2,ARHGEF7,CBS,ZFYVE9,CRY2,TOMM20,DNAL1,CACNG7,ACSL4,MED12L,NEU3,ZNF181,KCTD6,SON,ZBTB43,POGZ,TNR,DHX33,KAT6A" MicroRNA hsa-miR-877-5p:TargetScan hsa-miR-877-5p TargetScan 1.56E-08 8.75E-05 2.24E-08 2.06E-07 20 89 "BEND6,KIF6,ATP2B1,DPY19L3,CLTC,NCOR1,CSNK1G3,FSD1L,FOXM1,ANKFY1,CYP46A1,IL1RAPL1,KAT7,FRMD3,ARHGAP19,PBRM1,SCN3A,NMNAT2,KIAA0930,RFTN2" MicroRNA hsa-miR-744-5p:TargetScan hsa-miR-744-5p TargetScan 1.58E-08 8.88E-05 2.27E-08 2.09E-07 12 31 "CSMD2,PLEKHG5,BIN1,KCNAB3,FAM57B,EGR3,GRIN2D,HPSE2,DBNL,NFIX,NRGN,PPP5C" MicroRNA hsa-miR-302c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-08 9.03E-05 2.31E-08 2.13E-07 26 144 "INTS2,MAP4K4,VCAN,GAPVD1,MATR3,SH3GLB1,FAM13A,GABRB1,MTHFD2,WASF3,TNRC6A,ZNF638,EML4,PLCL1,TNPO2,CRLS1,CEP97,ZYG11B,SATB1,MYO18A,SHC4,FNDC3A,CADM1,UBE2H,ZBTB38,EML6" MicroRNA hsa-miR-138-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.64E-08 9.19E-05 2.35E-08 2.16E-07 24 125 "CCAR2,CDH2,IGLON5,BAG4,ZEB2,PLEKHM1,DNAJB6,FEM1B,CELF1,ZMYND11,FERMT2,GRID1,NR3C1,PPM1L,NEUROD1,ZNF426,RELN,PTK2,RGS12,C12orf49,YPEL4,SIRT1,MEAF6,KCNK12" MicroRNA hsa-miR-8066:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-08 9.48E-05 2.42E-08 2.23E-07 21 98 "NLGN4X,SLC7A14,CA8,COPB2,UBXN2A,SV2B,MTX3,EIF5,BSCL2,KIF3A,CCDC80,DDR2,PDE3A,USP47,UBR7,SLC25A36,SATB1,NPAS3,SYPL1,WBP2,TRPS1" MicroRNA hsa-miR-4526:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-08 9.62E-05 2.45E-08 2.26E-07 18 73 "SLC25A25,INTS2,TRIM41,CCNT1,PPP1R16B,PLEKHM1,RPS6KL1,AMOTL2,B4GALNT1,SESN1,LSAMP,CHIC1,NODAL,GPSM2,PRKACB,TMEM200C,TMEM151B,UPF3A" MicroRNA hsa-miR-615-3p:mirSVR_highEffct hsa-miR-615-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.71E-08 9.62E-05 2.45E-08 2.26E-07 18 73 "SUGT1P4-STRA6LP-CCDC180,APOC1,BBS2,SCARB1,SLC32A1,PTK2B,NELFCD,NRG3,MAP7D2,CLASRP,RASSF8,PPARA,RNF220,SEC14L1,ITSN1,SMARCE1,RCOR3,CFAP298" MicroRNA hsa-miR-1470:mirSVR_highEffct hsa-miR-1470:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-08 9.62E-05 2.45E-08 2.26E-07 18 73 "GALNT16,KSR1,DDR1,CDH18,DLG2,DPP6,GPR61,RAB30,C2orf72,ZNF678,KCNJ3,KLC1,LOC100128239,NTNG1,SIRT2,KDM4C,PEG10,CLIP2" MicroRNA hsa-miR-5586-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-08 9.90E-05 2.52E-08 2.33E-07 30 185 "SLC24A4,KIAA1324,CLU,COL9A2,SOCS5,GREB1,TMEM170A,WDR20,RABEPK,ZNF549,GABRB1,TRAF3IP2,ZNF234,DDX19B,DOCK7,ZNF678,KCNN3,ZFYVE27,COMMD5,NUCB2,OLR1,GPR137C,STK32A,NKAIN1,RAB5B,ZNF331,IL17RB,MAGI3,EMC1,GSE1" MicroRNA hsa-miR-500b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-08 1.05E-04 2.68E-08 2.47E-07 16 58 "MTUS1,ASGR1,ZBTB10,CCNT1,LONRF2,SPATA2,NTM,ZNF585B,HHIPL1,FAXC,OS9,HSP90AA1,SLC35G1,KCNN3,RICTOR,LYPD6" MicroRNA hsa-miR-3675-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-08 1.07E-04 2.72E-08 2.51E-07 27 155 "FZD9,PTCHD1,KIAA1324,PDZD4,MARK4,MYOM2,CTH,KIAA0513,FBXO25,NCKAP1,SAMD5,CCDC80,TBC1D25,FAT3,PTPRB,RORB,SNX22,SCN7A,MAGI3,EPB41L3,SYT11,DNAJC9,ALG1,CRTC1,SLC44A1,ZNF70,URM1" MicroRNA hsa-miR-28-3p:TargetScan hsa-miR-28-3p TargetScan 1.91E-08 1.07E-04 2.73E-08 2.52E-07 20 90 "RNF182,CACNA1G,FHL5,LETMD1,KIAA0408,MATR3,DTNA,EFEMP1,FOXO3,LUZP2,MEIS1,DDR2,GPR85,RAD51D,ATXN7,AHCYL2,BHLHB9,GOPC,CERS6,GAN" MicroRNA hsa-miR-192-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-08 1.08E-04 2.75E-08 2.54E-07 24 126 "KIF6,SLC7A14,NRXN3,CSNK1G3,IST1,ABI2,EMX2,CELF1,CAB39,NR3C1,ZNF546,KCNQ3,LSAMP,NTRK3,PDE3A,KANSL1,SNRK,RNASEL,SCP2,MRAS,SNAP25,FBXW11,ARL10,FXR1" MicroRNA hsa-miR-628-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-08 1.12E-04 2.85E-08 2.63E-07 15 51 "TTYH1,ARID1A,TRIM41,RTTN,KIAA0408,TOMM20,PLEKHM1,SEMA3D,IRAK4,CRCP,MAOB,MBNL1,PDGFRA,CHD9,NELFE" MicroRNA hsa-miR-1296-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-08 1.15E-04 2.92E-08 2.69E-07 21 99 "ARRB2,UBXN2A,PHYHIP,IP6K1,TOM1,EFNA3,ING4,SESN1,MIER3,TJAP1,IBA57,PFKFB2,PKM,SMOX,KIAA0895L,SBF1,SCN2B,COPZ1,BTBD3,SLC19A3,UBTF" MicroRNA hsa-miR-448:Functional MTI Functional MTI miRTarbase 2.04E-08 1.15E-04 2.92E-08 2.69E-07 21 99 "ARID1A,THSD7A,TBPL1,USP6NL,DAPK1,ACSL4,MMADHC,COPS8,KDM2B,GRIK3,P2RY1,PIK3R1,PURG,CEP97,SETD5,SATB1,HSPA4L,ZBTB43,SS18,SEPT8,FXR1" MicroRNA hsa-miR-7856-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-08 1.17E-04 2.97E-08 2.73E-07 25 136 "SDE2,OSBPL6,TAOK1,ZBTB10,LDLRAD4,MYADM,LIN54,IP6K1,GORAB,BRPF3,COMMD5,PCMT1,PIK3R1,CEP97,RBBP6,GTDC1,EXD2,TMCC1,MYT1L,ITPRID2,SEPT3,CRB1,LEFTY2,TPD52,FZD3" MicroRNA hsa-miR-886-5p:mirSVR_highEffct hsa-miR-886-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.10E-08 1.18E-04 3.00E-08 2.76E-07 17 66 "CACNA2D1,MTMR7,IQCK,DNAH9,SYT3,CAMKK2,NSG1,GAREM2,KCTD6,NTRK2,MTMR10,ATAT1,TRIM46,ITSN1,CCDC92,TUBB1,ATP6V0E2" MicroRNA hsa-miR-1233-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-08 1.19E-04 3.03E-08 2.79E-07 31 197 "PHF12,LONRF2,SUMF2,CRY2,FAM131B,DCAF8,TOMM20,IP6K1,E2F6,PHC2,TMTC1,EFNA3,ABI2,AHDC1,IRAK3,NEGR1,KCNK3,NRGN,PDGFRA,PFKFB3,PMP22,PPARA,KLHDC8A,MRAS,SLC11A1,CAMTA2,RPRM,UBTF,KLC2,CIAPIN1,WNK2" MicroRNA hsa-miR-8082:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-08 1.19E-04 3.03E-08 2.79E-07 31 197 "ANK1,SEMA7A,DOCK11,CAMK2A,CTNND1,SPATA2,EPS8,TUBA1B,TRAF3IP2,FAXC,TNRC6A,GLUL,RAB40B,KCND3,GPR155,OLA1,ZNF426,CEP97,SLC25A36,ELP2,HSD11B1L,SCN2B,ELMOD1,HSPA4L,NUBPL,FAM126B,NFASC,KIAA0930,RPL7L1,ZNF708,KAT6A" MicroRNA hsa-miR-6870-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-08 1.21E-04 3.08E-08 2.84E-07 18 74 "BEND6,G3BP2,EIF5,ANKMY1,PCDH17,ZNF638,HMGB1,TBC1D25,HMGCLL1,TNPO2,KANSL1,CNNM2,SH3TC2,TMEM100,SMARCE1,ELOVL4,ZNF195,SIGLEC10" MicroRNA hsa-miR-499b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-08 1.21E-04 3.08E-08 2.84E-07 18 74 "SERPINA3,HECW2,COL9A2,C2CD2,ABCC5,EN2,VPS13B,MRPL37,SESN1,PTPRT,FRMD5,SHISA6,HSP90AA1,KCTD6,FNDC3A,AGTPBP1,KCTD2,TFIP11" MicroRNA hsa-miR-1197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-08 1.21E-04 3.08E-08 2.84E-07 18 74 "TEX22,ATP1B3,KALRN,NOS1AP,LONRF1,PLEKHM1,ZNF391,ANKFY1,ZSCAN2,SETD5,ATAT1,GALNT10,SLIT1,AJAP1,TRIM2,SLC44A1,UBTF,UGT8" MicroRNA hsa-miR-593-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.16E-08 1.22E-04 3.09E-08 2.85E-07 28 166 "SPAG9,FMNL3,USP6NL,TMEM170A,C2CD2L,ERBB2,UFM1,NCKAP1,SCIN,SYTL4,LSAMP,PALM,PDE3A,STRN3,BSDC1,NCBP3,TRA2B,FAM214B,MCF2L2,DIP2A,FAM208A,KIAA0930,SZT2,HHIP,TPM3,ZNF708,NAV2,PLSCR4" MicroRNA hsa-miR-4495:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-08 1.27E-04 3.22E-08 2.97E-07 24 127 "APP,CCDC74A,ZBTB10,ATP2A2,FOXK1,FSD1L,EIF5,TUBD1,SCML2,MMADHC,C5orf24,MYBPC1,SH3TC2,SEC61A2,ALG9,PGBD4,UEVLD,FBXW7,BDP1,SYPL1,XPO1,FAM182B,PHTF2,NETO2" MicroRNA hsa-miR-3692-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.26E-08 1.27E-04 3.22E-08 2.97E-07 24 127 "SORCS2,FOXK1,THSD7A,QKI,TOGARAM2,NOS1AP,GAPVD1,TIAM2,CALN1,CPEB2,FDFT1,APOPT1,ZNF496,NCKAP1L,LIFR,MYO6,PLCL1,PRKACB,RXRA,ANKRD12,TPCN2,CADM1,ZNF138,ZXDA" MicroRNA hsa-miR-4791:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-08 1.28E-04 3.26E-08 3.00E-07 13 38 "CA8,CDC25B,ELAVL2,CELF1,KCNMB4,GRIK2,BACH2,PRRX1,PTPRD,CEP97,MBD5,PCDHA6,PARD3" MicroRNA hsa-miR-4766-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-08 1.28E-04 3.26E-08 3.00E-07 13 38 "MAP7,SPATA2,CPEB2,SESN1,PTPRT,C5orf24,IL6ST,FIGN,KCNIP3,ACSBG1,CLASP1,RGMB,GAN" MicroRNA hsa-miR-720:PITA hsa-miR-720:PITA_TOP PITA 2.29E-08 1.29E-04 3.26E-08 3.00E-07 10 21 "CACNA1A,KMT2C,HECTD1,FOXG1,AGAP2,MSI1,KCTD15,ANKRD16,SST,SLC44A1" MicroRNA hsa-miR-2052:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.33E-08 1.31E-04 3.32E-08 3.06E-07 20 91 "CACNB2,LONRF1,DMD,CELSR3,TNRC6A,CBX1,RASSF8,IL6R,MAT2A,MDM4,ZSCAN2,FBXW7,CHD9,PEX26,ZEB1,FAM200B,ZNF384,STXBP4,ZNF28,ZXDA" MicroRNA hsa-miR-1233:PITA hsa-miR-1233:PITA_TOP PITA 2.33E-08 1.31E-04 3.32E-08 3.06E-07 20 91 "FMNL2,AXIN2,SEMA4G,FMNL3,ARHGEF1,DLGAP2,CREB5,MYEF2,ABCC5,PHC2,FGF13,AHCYL1,AGFG1,NEK1,PIK3R1,ROBO1,SMPD3,CASC3,FAM214B,ZFP91" MicroRNA hsa-miR-210:PITA hsa-miR-210:PITA_TOP PITA 2.41E-08 1.36E-04 3.44E-08 3.17E-07 12 32 "ELFN2,SEMA6A,EFNA3,RCAN2,MDGA1,NCAM1,NEUROD2,NPTX1,ZNF827,SEMA5B,SLC8A3,CAMTA1" MicroRNA hsa-miR-4428:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-08 1.36E-04 3.44E-08 3.17E-07 25 137 "TTLL9,TOGARAM2,ZNF385A,CNTNAP2,SLITRK5,EN2,WAC,MSL1,C2CD4C,ITPKB,MID1,MOG,PABPC1L2A,CDK14,PRRT2,RFX3,MYH14,SHMT2,RUFY2,LGI3,ZFP1,FAM168A,TPM3,CADM1,SF1" MicroRNA hsa-miR-3937:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-08 1.37E-04 3.48E-08 3.21E-07 16 59 "LTBP4,ARHGDIA,CD81,TMEM184B,IGDCC3,ZNF385A,NCOR2,PHYHIP,ABI2,B4GALNT4,IRAK3,SEPT4,ZNF532,KCNIP3,CLSTN1,CBX5" MicroRNA hsa-miR-1179:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-08 1.37E-04 3.48E-08 3.21E-07 16 59 "HACE1,TOGARAM2,CREB5,LIN54,MAML1,DMPK,PLEKHA1,FOXO3,NR3C1,HMGB1,NEGR1,BLOC1S2,NFIX,PCSK1,SDK2,DIP2A" MicroRNA hsa-miR-1236-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-08 1.37E-04 3.48E-08 3.21E-07 16 59 "ARHGDIA,INSYN2B,ADGRG1,IST1,RPS6KL1,SLC6A17,ZFYVE21,PTPA,RBBP8,ZFP1,GSE1,CAMSAP2,USP22,TUBB2A,UPF3A,TMEM63C" MicroRNA hsa-miR-4690-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.46E-08 1.38E-04 3.50E-08 3.22E-07 21 100 "ALDH4A1,KALRN,NEURL1,CS,DYRK1A,HEYL,EBI3,LYVE1,NCKAP1L,METTL21A,MMP17,VWA2,PDE2A,ZDHHC8,PIK3CD,PRRT2,IGSF9B,PBLD,KIAA0930,TPM3,ZBTB16" MicroRNA hsa-miR-4753-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.48E-08 1.39E-04 3.52E-08 3.24E-07 22 109 "SDE2,ADARB2,ADCY5,ZFYVE9,CRY2,LRIG1,CEP170,EIF5,WAC,TACC2,SLC35G1,KCNN3,OCRL,PAK3,SDK2,SLC25A36,R3HDM2,INAVA,TCF7L2,NSD1,VAV2,NETO2" MicroRNA hsa-miR-6501-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.52E-08 1.41E-04 3.58E-08 3.29E-07 27 157 "AXIN2,GRAMD1B,NLGN4X,KIF6,BARD1,DDR1,USP2,ARHGAP32,TMEM170A,E2F5,ATP8A2,CRCP,GPR75,TNRC6A,IPO5,MN1,SLC11A2,KLHDC8A,CCDC25,SLC1A7,PEX26,PDZD2,TROVE2,AGTPBP1,TMEM9,SSBP2,TBC1D15" MicroRNA hsa-miR-6836-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-08 1.49E-04 3.76E-08 3.46E-07 24 128 "PNMA8B,SEMA7A,CPNE5,LDLRAD4,CANX,BRSK2,FAM131B,DLC1,PDLIM5,CPLX1,CACFD1,MAP4,MSI1,PKD1,PACSIN1,RAB5B,SALL1,HES6,PEX26,NFASC,CLASP1,MEAF6,GDPD5,HNRNPA3" MicroRNA hsa-miR-6132:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.65E-08 1.49E-04 3.76E-08 3.46E-07 24 128 "PNMA8B,SEMA7A,CPNE5,LDLRAD4,CANX,BRSK2,FAM131B,DLC1,PDLIM5,CPLX1,CACFD1,MAP4,MSI1,PKD1,PACSIN1,RAB5B,SALL1,HES6,PEX26,NFASC,CLASP1,MEAF6,GDPD5,HNRNPA3" MicroRNA hsa-miR-95:mirSVR_highEffct hsa-miR-95:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.65E-08 1.49E-04 3.76E-08 3.46E-07 24 128 "SLC12A5,PPP4R4,CACNA1E,RGS6,HDAC9,ADGRV1,FAM184B,GCNT2,HTR5A,KNDC1,MID1,GPR88,PURG,PRKACB,QDPR,ZYG11B,GTDC1,DOCK10,INKA2,TPM3,C9orf85,DCBLD1,TTC3,PDSS2" MicroRNA hsa-miR-181b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-08 1.51E-04 3.80E-08 3.50E-07 17 67 "ADARB2,INSYN2B,SLC2A11,LONRF2,SRSF11,CLTA,QKI,NSL1,ELMSAN1,ZIC4,GABRB1,GLUL,CNDP1,SLC37A2,TLR4,FAM124A,RPL7L1" MicroRNA hsa-miR-181b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-08 1.51E-04 3.80E-08 3.50E-07 17 67 "ADARB2,INSYN2B,SLC2A11,LONRF2,SRSF11,CLTA,QKI,NSL1,ELMSAN1,ZIC4,GABRB1,GLUL,CNDP1,NFASC,SLC37A2,FAM124A,RPL7L1" MicroRNA hsa-miR-4423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-08 1.56E-04 3.95E-08 3.64E-07 32 210 "AS3MT,TMEM132B,ESYT2,ISPD,AKAP5,CSNK1G3,SEC14L5,MRNIP,COQ7,LILRA2,GPR45,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,NUCB1,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,PEX26,FAM126B,PSD3,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA hsa-miR-25-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.78E-08 1.56E-04 3.95E-08 3.64E-07 32 210 "TRMT9B,ASPA,FOXK1,CACNA1B,CDR1,JAM2,PLAA,CLU,NCOR2,MICAL2,PHYHIP,ELAVL3,FECH,KBTBD12,NCKAP1,MDM4,NFIX,PIK3CD,FXYD1,PRKCZ,RBBP8,PTGR2,FNIP1,LIMS2,FNBP1,MCF2L2,FBXL16,TPM3,SSBP2,RFTN2,USP1,TBC1D15" MicroRNA hsa-miR-3194-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.81E-08 1.58E-04 3.98E-08 3.67E-07 25 138 "AS3MT,ISPD,TBRG4,TBPL1,KIAA0408,DBT,GOLGA7,ELAVL2,MSANTD4,GSN,KPNA5,LIMS1,GPR155,MKLN1,PAX6,SEPT4,ELMOD1,HSPA4L,KLHL7,ARL10,ERCC6L2,PARD3,ZNF74,ZNF154,WNK2" MicroRNA hsa-miR-326:Functional MTI Functional MTI miRTarbase 2.81E-08 1.58E-04 3.98E-08 3.67E-07 25 138 "SORCS2,BMP7,CLU,SEZ6,SRRM1,ERBB2,FGF1,MTHFD2,BVES,ATXN2L,MAT2A,PDE3A,PDE1B,PKM,PTPA,BCAS3,VPS13C,STUM,MYH15,PSD3,FBXL16,SSBP2,ZNF154,CSDE1,JMJD1C" MicroRNA hsa-miR-6769b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-08 1.59E-04 4.01E-08 3.69E-07 28 168 "PNMA8B,TAOK1,BCL7A,DIRAS1,PITPNM3,CELSR3,APH1A,ABI2,GLI2,SOWAHA,METTL21A,MDFI,MPP2,NFIX,NUCB1,GPR173,RETREG2,RAB5B,CEP97,FOXRED2,ATXN2,SLIT1,UNC5B,SPART,CLASP1,RICTOR,ZNF708,ZNF28" MicroRNA hsa-miR-1281:mirSVR_highEffct hsa-miR-1281:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.84E-08 1.59E-04 4.02E-08 3.70E-07 20 92 "ASPHD1,VSTM2A,LDB2,AIFM1,CDH18,SEC24C,DNM1L,SYNCRIP,TMEM25,KCNK2,MSRA,FAM216A,SIDT1,PTPRD,HSD11B1L,ST3GAL3,SPTB,AMACR,DCBLD1,UPF3A" MicroRNA hsa-miR-4457:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-08 1.66E-04 4.18E-08 3.85E-07 22 110 "SLC25A25,TXNDC16,ANK1,ZNF555,DLGAP3,TOGARAM2,GREB1,NOS1AP,TM9SF4,SYTL4,ZNF713,P2RY1,PDE4D,PCMTD2,CSRNP3,POGZ,DIP2A,ACSBG1,IQCE,NSD1,SLC38A1,GAN" MicroRNA hsa-miR-3617-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.96E-08 1.66E-04 4.19E-08 3.86E-07 21 101 "SDE2,KLHL32,AXIN2,ANK1,THSD7A,CANX,LIN54,GOLT1B,DLC1,IQGAP2,P2RY1,MAPK10,FIGN,NBPF1,ANKRD36,LIMCH1,POGZ,FGD4,SLC35G2,ZNF106,CLDND1" MicroRNA hsa-miR-4762-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-08 1.74E-04 4.39E-08 4.04E-07 24 129 "TMEM132B,INTS2,ZBTB10,BTRC,CACNA1A,ZBED1,CEP170,WASF3,ARHGAP19,MITF,PAK3,ENPP2,FAM98B,OLA1,PLCB2,PKIA,CNNM2,SCP2,BTBD3,FAM126B,FNDC5,PRDM10,CERS6,JMJD1C" MicroRNA hsa-miR-1227-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-08 1.75E-04 4.42E-08 4.07E-07 32 211 "XKR4,AMER3,CBS,MYOM2,NRXN3,HINFP,RASSF2,DNAL1,SPATA2,MTX3,ATP13A4,SLC2A6,DDX19B,IBA57,CHST6,MDM4,ZC3H12B,RBBP8,TRIM68,MAGI3,BTBD3,SEPHS1,ATF7IP,IGSF9B,EMC1,SSTR2,USP22,PPIL6,SSBP2,RPL7L1,UGT8,SLC30A4" MicroRNA hsa-miR-6501-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-08 1.75E-04 4.42E-08 4.07E-07 32 211 "AS3MT,TMEM132B,ESYT2,ISPD,AKAP5,CSNK1G3,SEC14L5,MRNIP,COQ7,CELF1,LILRA2,GPR45,ZNF546,SCIN,IBA57,CREG2,MKLN1,LAYN,NUCB1,ZNF713,OLA1,ELP2,SNX22,HSPA4L,ZFP30,FAM126B,PSD3,GPR161,ZNF708,ZNF154,RNF170,AP3B2" MicroRNA hsa-miR-516b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-08 1.78E-04 4.47E-08 4.12E-07 19 84 "DPY19L3,MYRF,CANX,CLCN3,DCAF4,TMEM151A,GNAS,PLD5,IL6ST,KLHL23,NASP,NFIX,PRRX1,C1orf109,NCBP3,MYO18A,ZC3H4,NACC2,CLDND1" MicroRNA hsa-miR-3166:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.16E-08 1.78E-04 4.47E-08 4.12E-07 19 84 "SLC24A4,IGDCC4,ARHGDIA,PRC1,COL9A1,PREPL,PLXNA4,PHF19,IP6K1,ABCC5,CSDC2,FERMT2,PCLO,CYP27C1,AFF1,PLXNB1,CEP97,COPZ1,VSNL1" MicroRNA hsa-miR-663b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-08 1.79E-04 4.50E-08 4.14E-07 16 60 "ELFN2,CARNS1,ANK1,FOXK1,SOCS5,EEF1A2,HRASLS5,IL1RAPL1,MPP2,MRPS18A,BTBD3,KIF21B,DDN,SEPT8,ZC3H4,TBCEL" MicroRNA hsa-miR-4642:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.18E-08 1.79E-04 4.50E-08 4.14E-07 16 60 "ARID1A,ARHGEF7,CFAP410,CACNA2D1,CCNT1,GNAS,PARD3B,KAT7,EID2B,KCNJ11,MYCN,OLA1,CNNM2,DPF2,STX1B,TMPO" MicroRNA hsa-miR-6771-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-08 1.81E-04 4.56E-08 4.20E-07 28 169 "ABCF1,AS3MT,NDRG3,SLC24A4,TXNDC16,APAF1,ATM,ADGRB2,IPCEF1,TMEM170A,RASA4,MRNIP,VPS26C,ZNF589,MTHFD2,GNAS,BVES,QDPR,GSTCD,PTGR2,SEPHS1,FAM208A,AKNA,CBX5,TPM3,TBC1D15,ZNF28,TFIP11" MicroRNA hsa-miR-1288-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-08 1.84E-04 4.62E-08 4.26E-07 13 39 "ESYT2,CREM,E2F6,FLYWCH1,CAB39,RNF165,LINC01551,KCNH2,NFIX,OPHN1,PCSK2,KCTD15,WIPF1" MicroRNA hsa-miR-6794-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.31E-08 1.86E-04 4.68E-08 4.31E-07 27 159 "TEX22,PHF12,CDK13,C2CD2,RGS6,SUSD5,DBT,TMCC2,COQ7,SRARP,SLC37A3,CNDP1,KAT7,ZDHHC15,NKD1,GPR137C,PPP2R5E,ELP2,CHD9,ANKRD36,UNC5B,ZC3H13,INKA2,KLHL4,TMEM151B,FBXL16,ZNF708" MicroRNA hsa-miR-7152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-08 1.88E-04 4.72E-08 4.34E-07 23 120 "ADD1,TNRC6C,PRX,THSD7A,LRRFIP1,PITPNM3,TM9SF4,IRAK4,DLC1,UFM1,PDLIM5,LILRA2,KPNA5,MEIS1,MTRF1L,RCOR3,SP4,CLSTN2,GANAB,ACSBG1,VAMP1,EXOC7,ZNF138" MicroRNA hsa-miR-4694-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-08 1.88E-04 4.72E-08 4.34E-07 23 120 "OGT,LDHD,WASF1,FOXK1,DLGAP3,CPS1,PYGO1,FEM1B,RTN3,SCML2,SYNCRIP,MSANTD4,MAT2A,MBNL1,PCSK2,PKM,REV3L,SLC6A8,ZSCAN29,TLR4,LRRC8A,TPD52,FXR1" MicroRNA hsa-miR-1279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-08 1.90E-04 4.77E-08 4.39E-07 18 76 "ATM,DBT,EDN1,ANKRD46,WAC,NR3C1,FRMD3,SESN3,ZFYVE21,PURG,C12orf49,AJAP1,SYPL1,VLDLR,CLDND1,LYPD6,WNK1,MFF" MicroRNA hsa-miR-155-3p:Functional MTI Functional MTI miRTarbase 3.40E-08 1.91E-04 4.80E-08 4.42E-07 17 68 "ATP1A1,SYT6,CREB5,EPB41,ERBB2,CDHR1,MRVI1,IRAK3,SHC3,MYO6,NFIX,GTDC1,KIRREL1,FBXW7,TCF7L2,SIRT1,TPM1" MicroRNA hsa-miR-5706:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-08 1.91E-04 4.80E-08 4.42E-07 17 68 "DPY19L3,MYRF,CANX,CLCN3,DCAF4,TMEM151A,GNAS,IL6ST,PRRX1,SEPT4,TNPO2,C1orf109,MYO18A,ZNF621,ZC3H4,NACC2,SLC30A4" MicroRNA hsa-miR-4782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-08 1.91E-04 4.80E-08 4.42E-07 17 68 "DPY19L3,MYRF,CANX,CLCN3,DCAF4,TMEM151A,GNAS,IL6ST,PRRX1,SEPT4,TNPO2,C1orf109,MYO18A,ZNF621,ZC3H4,NACC2,SLC30A4" MicroRNA hsa-miR-208b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.50E-08 1.97E-04 4.94E-08 4.55E-07 22 111 "PCDH19,CDH2,LRIG1,SOCS5,SYNCRIP,UFM1,SRRM4,MSTN,SLC2A6,RBPJ,SLC35G1,MTRF1L,PTAFR,CEP97,ATP8B4,KIF21A,SNAP25,SON,HEY2,LRRC8A,JMJD1C,ZDHHC20" MicroRNA hsa-miR-1184:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.50E-08 1.97E-04 4.94E-08 4.55E-07 22 111 "PHF12,NUMB,STX16,TMEM184B,TMEM170A,DCC,ZBTB24,TMEM132C,GLUL,ATOH8,IDH3A,IL6R,IBA57,ENPP2,DRAXIN,SMARCE1,BDP1,DICER1,WBP2,UBE2H,SF1,SLC30A3" MicroRNA hsa-miR-6857-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.55E-08 1.99E-04 5.00E-08 4.61E-07 21 102 "PPFIA4,ARRB2,CACNB2,TPP1,KLHL3,APH1A,HBS1L,SRCAP,TNRC6A,SCIN,KCNN3,MSI1,NBL1,SLC25A23,DRAXIN,COPZ1,UNC5B,FAM168A,CBX5,LAT2,CIAPIN1" MicroRNA hsa-miR-1247:PITA hsa-miR-1247:PITA_TOP PITA 3.61E-08 2.03E-04 5.09E-08 4.69E-07 9 17 "WAC,TAOK3,BRSK1,TNRC6A,ATXN1,IGSF9B,MYCBP2,LRRC4,POLR3H" MicroRNA hsa-miR-572:PITA hsa-miR-572:PITA_TOP PITA 3.61E-08 2.03E-04 5.09E-08 4.69E-07 9 17 "PITPNM2,BCL2L2,VSTM2A,DGKG,PPARGC1A,NCAM1,NFIX,TMEM260,FAM155A" MicroRNA hsa-miR-575:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-08 2.03E-04 5.09E-08 4.69E-07 24 130 "API5,ATP2A2,NEURL1,UBXN2A,DBN1,RACK1,TRAF3IP2,MYOZ2,CRCP,GRK4,CHST6,MKLN1,ZNF680,FAT3,POLR2F,UEVLD,KCNIP2,NCBP3,AKNA,RBFOX2,USP1,MEAF6,DHX33,MSRB3" MicroRNA hsa-miR-3915:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-08 2.03E-04 5.09E-08 4.69E-07 24 130 "ELFN2,APBB2,ASTN1,ALDH4A1,CACNA1B,FMNL3,GAPVD1,RAB39B,SYNCRIP,KIF3A,MIER3,ZFYVE27,PDE3A,ZNF426,C1orf109,SH3TC2,OXR1,KLHL11,ELP2,NMNAT2,ZC3H4,ZMAT3,TNS1,RASD2" MicroRNA hsa-miR-4676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-08 2.03E-04 5.09E-08 4.69E-07 24 130 "API5,ATP2A2,NEURL1,UBXN2A,DBN1,RACK1,TRAF3IP2,MYOZ2,CRCP,GRK4,CHST6,MKLN1,ZNF680,FAT3,POLR2F,UEVLD,KCNIP2,NCBP3,AKNA,RBFOX2,USP1,MEAF6,DHX33,MSRB3" MicroRNA hsa-miR-451b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.83E-08 2.15E-04 5.40E-08 4.97E-07 26 150 "ARMC12,TPP1,AKAP12,PUM1,ST18,TMEM170A,TRMO,CRCP,GPR75,MSL1,CREG2,LAMP2,LIFR,CHST6,ADAM22,SLC11A2,PLEKHB2,KLHDC8A,PEX26,IQCE,CRTC1,ZMAT3,SMUG1,SSBP2,TBC1D15,VANGL2" MicroRNA hsa-miR-640:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.85E-08 2.16E-04 5.41E-08 4.99E-07 31 202 "AS3MT,BRAP,ZNF578,TAOK1,CACNB2,STOML1,EIF5,APOPT1,HAS2,ATCAY,C2orf72,MAN2A2,CHST6,P2RX7,TMOD2,ZNF426,ZSCAN2,NWD1,DCUN1D2,KLHDC8A,NUBPL,ZNF430,SLC15A2,ANKRD36,TMCC1,CLUAP1,ZBTB43,ZNF34,USP1,ZNF708,MPPE1" MicroRNA hsa-miR-589-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-08 2.18E-04 5.46E-08 5.03E-07 19 85 "RASL11B,LRIG1,EPS8,SCML2,FGF1,DOT1L,BDNF-AS,ZNF844,SETD5,RPL15,SEMA6D,DHX30,NPAS3,ZNF621,TBL1X,DAAM2,TRPC3,UBTF,ZNF189" MicroRNA hsa-miR-886-3p:mirSVR_highEffct hsa-miR-886-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.88E-08 2.18E-04 5.46E-08 5.03E-07 19 85 "TTLL9,LDB2,HS3ST5,SH2B1,CCDC144A,DAPK1,ANKRD13B,CHST15,USP19,ZNF276,TJAP1,KCNK1,NLGN3,KCTD17,NUBPL,MPRIP,ANO4,THRA,PRDM2" MicroRNA hsa-miR-3151-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-08 2.18E-04 5.46E-08 5.03E-07 19 85 "TRMT9B,AMPD3,CACNA2D2,TMEM184B,PYGO1,TOM1,ELN,MAP4,NKX2-2,PLEC,SLC25A23,SDK2,KIAA0895L,ATXN2,SCN2B,COPZ1,SMTN,PEG10,NACC2" MicroRNA hsa-miR-339-3p:PITA hsa-miR-339-3p:PITA_TOP PITA 4.00E-08 2.25E-04 5.63E-08 5.19E-07 10 22 "RNF150,ADGRB1,PNKD,RGS6,SALL3,SCRT2,ARX,DDN,RIMBP2,BEST1" MicroRNA hsa-miR-6509-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.11E-08 2.31E-04 5.77E-08 5.32E-07 16 61 "FAM135A,PTBP2,CCNT1,FOXN3,TMEM170A,CELF1,IL6R,SLC35G1,MYCN,NAP1L1,SNX10,PPP1R1A,CNNM2,BTBD3,AP4E1,RICTOR" MicroRNA hsa-miR-103b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.11E-08 2.31E-04 5.77E-08 5.32E-07 16 61 "FOXK1,CA12,CRY2,LIN54,DMTF1,SPECC1,GSN,MSL1,PPM1L,GPSM2,ZYG11B,GLDN,NCBP3,SPART,KLHL7,RPL7L1" MicroRNA "TACAATC,MIR-508:MSigDB" "TACAATC,MIR-508:MSigDB" MSigDB 4.11E-08 2.31E-04 5.77E-08 5.32E-07 16 61 "CPNE2,SORCS1,NUMB,SEPT7,PHYHIPL,MSTN,GRIA2,GRM8,MITF,SATB1,ABLIM3,LMO3,CLASP1,ARHGEF12,RNF103,PHTF2" MicroRNA hsa-miR-376a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.15E-08 2.33E-04 5.83E-08 5.37E-07 22 112 "MYRF,FOXK1,INA,SRSF11,BTF3L4,RIMS2,YAF2,AMOTL2,FOXG1,GNAS,ATG4C,KCND3,KIF5C,CYP27C1,SHC3,PFKFB2,PIK3R1,ZNF426,ZNF844,ZNF667,SLC35G2,ZNF781" MicroRNA hsa-miR-5007-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.15E-08 2.33E-04 5.83E-08 5.37E-07 22 112 "ABCF1,VXN,TBRG4,TMEM184B,RTTN,SEC14L5,DBT,DNAH9,RGS17,COQ7,C1orf61,SPECC1,SRCAP,SCIN,IBA57,MBD1,MOG,C10orf105,PIK3R1,MTMR10,TMEM136,SATB2" MicroRNA hsa-miR-432-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-08 2.34E-04 5.84E-08 5.38E-07 20 94 "ADAR,CASKIN1,OGT,ATM,DST,PDE4DIP,DNAJB6,STAMBP,GNAS,PCLO,C10orf105,NUCB2,KIF21A,KDM4C,UNC5B,ADAMTS17,RBFOX2,ANO5,TUBB2A,CSDE1" MicroRNA hsa-miR-8081:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.16E-08 2.34E-04 5.84E-08 5.38E-07 20 94 "OGT,DNAH17,CD86,USP6NL,LONRF1,ANKRD46,CELSR3,SRARP,STAG2,RNF165,PLD5,SHMT2,ST6GAL1,SEPHS1,TMCC1,PDZD2,ERBIN,FAM168A,CYB561A3,JMJD1C" MicroRNA hsa-miR-3622b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-08 2.35E-04 5.87E-08 5.41E-07 28 171 "SDE2,SLC24A4,TXNDC16,ASPA,LDHD,CCNT1,KIAA1549L,RTTN,GNE,KRBA2,EGFR,ENPP6,ERBB2,MTHFD2,GNAS,CNDP1,AGBL5,GPR137C,OLA1,KCTD15,TMEM145,ZYG11B,FAM102A,KANK1,RFTN2,MGAT5B,ZNF70,ZNF189" MicroRNA hsa-miR-638:mirSVR_highEffct hsa-miR-638:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.20E-08 2.36E-04 5.89E-08 5.42E-07 18 77 "CPNE2,NCKAP5,ADGRF5,DACT3,NIPBL,SNCAIP,SPEG,STARD10,FUT10,KCNB1,MYO7A,WDR47,SNCB,SOX2,WDR7,AP4E1,PLPP4,ZNF195" MicroRNA hsa-miR-4733-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-08 2.38E-04 5.94E-08 5.47E-07 21 103 "DNAH17,ATP2A2,FMNL3,CDC25B,EVI5L,NCAN,DBT,DLC1,PRUNE2,GPR26,DDX19B,HMGB1,SEPT4,NDUFS7,SEC31A,TRIM67,ZNF106,ZNF781,ZNF154,TMEM237,ZNF195" MicroRNA hsa-miR-1286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-08 2.38E-04 5.94E-08 5.47E-07 21 103 "ADAR,BSN,DDR1,CLU,NCAN,BLOC1S6,SNX29,EN2,KIAA1109,GJB1,RABL2A,PACSIN2,SHISA6,KCNH2,MEIS1,FXYD6,PKM,SMOX,MTRF1L,MGRN1,GDPD5" MicroRNA hsa-miR-6777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-08 2.38E-04 5.94E-08 5.47E-07 21 103 "OSBPL1A,ZNF578,BCL2L2,VCAN,IP6K1,SIRPA,RCAN2,TBR1,GABRG2,HPR,NFYA,SMIM11A,PKD1,SH3TC2,SPIN3,EXOC7,PLEKHH2,AGMO,SPIRE1,PMEPA1,PPP1R3F" MicroRNA hsa-miR-6792-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-08 2.38E-04 5.94E-08 5.47E-07 21 103 "SPOP,VAT1L,SLC25A27,IP6K1,ELMSAN1,FEM1B,EN2,GABRA5,GNAL,NEGR1,LIMS1,SESN3,MYCN,PXK,ATXN1,HSPA4L,MYT1L,PARD3,TPD52,ITM2C,C12orf4" MicroRNA hsa-miR-329-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.24E-08 2.38E-04 5.94E-08 5.47E-07 21 103 "CA12,EPS15L1,CHD5,TBC1D5,ERBB2,DOT1L,FAXC,GNAL,ELOVL5,PLD5,P2RY1,GLIPR1L2,PDPK1,CNNM2,CNTLN,PEX26,ZNF384,FRRS1L,WRN,EMSY,SLC38A1" MicroRNA hsa-miR-4679:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-08 2.42E-04 6.03E-08 5.55E-07 17 69 "SDC3,DBN1,CHRDL1,RASGRP1,APC2,TOMM40L,ATP13A4,ADAP1,KLF12,HSP90AA1,MDM4,TTLL7,SEPHS1,SMOC1,KLHL7,TPD52L2,RPL7L1" MicroRNA hsa-miR-3064-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-08 2.42E-04 6.03E-08 5.55E-07 17 69 "ELFN2,PHF12,MARCH3,CD99L2,AASDH,TMTC1,POLR1B,TPK1,CELF1,RBPJ,MTR,CAMKV,PLCL1,SH3TC2,SLIT1,ZNF138,SPATA13" MicroRNA hsa-miR-627-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-08 2.42E-04 6.03E-08 5.55E-07 17 69 "OGT,BTF3L4,PPP1R16B,ST18,ANKRD46,APH1A,RNF165,PLD5,KANSL1,PTPRB,SHMT2,ST6GAL1,SEPHS1,KDM3A,FAM168A,CYB561A3,JMJD1C" MicroRNA hsa-miR-4531:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.37E-08 2.46E-04 6.12E-08 5.64E-07 25 141 "TEX22,CCNT1,NSL1,SIPA1L1,PDE4DIP,UBXN2A,TMEM170A,DUSP9,PHC2,TUBD1,FAM184B,KIAA1958,CNDP1,GRK4,BACH2,MAP2,CCDC80,C10orf105,NEUROD1,GPR137C,UHRF1BP1,SLC25A36,AHCYL2,ZFAND5,ITM2C" MicroRNA "GTAAGAT,MIR-200A:MSigDB" "GTAAGAT,MIR-200A:MSigDB" MSigDB 4.68E-08 2.63E-04 6.55E-08 6.03E-07 15 54 "QKI,IPCEF1,DYRK1A,DLC1,FGF13,NSG2,ARPP21,HMGB1,NFIA,NOVA1,PAX6,SGK1,UBE3A,NSD2,GAN" MicroRNA hsa-miR-4650-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-08 2.66E-04 6.64E-08 6.11E-07 19 86 "CSMD2,RNF157,DDR1,IP6K1,YTHDC1,ELMSAN1,PHC2,DNAJC27,NCKAP1,MTHFD2,GGT7,FUT10,TJAP1,PKM,SMOC1,NSFL1C,ZC3H4,CBX5,RBFOX2" MicroRNA hsa-miR-3653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.91E-08 2.76E-04 6.87E-08 6.32E-07 24 132 "TAOK1,ZBTB10,BAG4,TOMM20,ABI2,EIF4G2,TENM1,WAC,ACSL4,MIER3,LIFR,NCAM2,GDPD1,ZIK1,CEP97,ZYG11B,SETD5,TRAPPC13,BTBD7,PEG10,HHIP,UGT8,MPPE1,FZD3" MicroRNA hsa-miR-3162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-08 2.77E-04 6.89E-08 6.35E-07 14 47 "TAOK1,PHF12,MARK4,CACNA1G,CELSR3,TBR1,GPD1,KCNJ10,LSAMP,SDK2,ZNF793,PALLD,ERCC6L2,ZBTB16" MicroRNA hsa-miR-6769a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.96E-08 2.78E-04 6.93E-08 6.39E-07 27 162 "PNMA8B,TAOK1,BCL7A,DIRAS1,PITPNM3,CELSR3,APH1A,ABI2,GLI2,METTL21A,MDFI,MPP2,NFIX,NUCB1,GPR173,RETREG2,RAB5B,CEP97,FOXRED2,ATXN2,SLIT1,UNC5B,SPART,CLASP1,RICTOR,ZNF708,ZNF28" MicroRNA hsa-miR-338-3p:Functional MTI Functional MTI miRTarbase 5.05E-08 2.84E-04 7.07E-08 6.51E-07 25 142 "MIER1,ZNF582,GPR146,ISPD,CDH2,FAM131B,KIAA0513,ZEB2,TOM1,PLEKHA1,SCML2,SCARA3,GRIK3,MID1,NOVA1,BEST3,PKM,ALG9,ATAT1,SALL1,PREX2,ZKSCAN3,ZFP91,RFTN2,CCDC14" MicroRNA hsa-miR-6768-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-08 2.84E-04 7.07E-08 6.51E-07 21 104 "ADARB2,TAOK1,GOLGA7B,ZFYVE9,CLCN3,CRY2,RUBCN,CEP170,CDON,WAC,ZMYND11,KCNN3,JAKMIP3,OCRL,P2RY1,SLC25A36,INAVA,CAMSAP2,TCF7L2,RBFOX2,CADM1" MicroRNA hsa-miR-6827-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-08 2.84E-04 7.07E-08 6.51E-07 21 104 "ELFN2,AP1B1,HCN2,ADGRG1,TMEM184B,E2F6,EN2,EPB41L1,MTSS1L,ANKFY1,TNFAIP8L3,HMX1,NEGR1,NPTX2,PKD1,PTPA,RPS6KA2,PEAR1,CAMTA2,RPRM,VAV2" MicroRNA hsa-miR-509-3-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-08 2.84E-04 7.07E-08 6.51E-07 21 104 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,FOXM1,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,RAB5B,DRAXIN,RUFY2,BDP1,TCF7L2" MicroRNA hsa-miR-1225-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-08 2.84E-04 7.07E-08 6.51E-07 26 152 "ELFN2,KIF6,HCN2,GPR37L1,TMEM184B,KIAA0513,TOMM20,DMPK,ELAVL3,ZNF585B,NSG2,GPR75,MUM1,METTL21A,FTO,MSANTD2,RPS6KA2,RTKN,STX1B,CSRNP3,SCN4B,TAL1,SZT2,ARHGEF12,AHCYL2,TMEM63C" MicroRNA hsa-miR-6085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.20E-08 2.92E-04 7.25E-08 6.68E-07 18 78 "AP1B1,METTL6,TMEM184B,NCOR2,ANKRD13B,STAMBP,GJB1,PRRC2B,GRID1,KCNH2,PKD1,PKM,KCTD15,MTRF1L,PTPA,RAP1GAP2,SF1,INTS3" MicroRNA hsa-miR-4717-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.20E-08 2.92E-04 7.25E-08 6.68E-07 18 78 "ZNF578,HAPLN1,HIPK3,EN2,ZBED3,SPECC1,TPK1,SEPT9,ADAM28,QDPR,BSDC1,PNMA8A,STUM,ALG1,NACC2,TPM3,WRN,ZDHHC20" MicroRNA hsa-miR-6869-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.39E-08 3.03E-04 7.53E-08 6.93E-07 23 123 "CD86,CLTA,RNF14,UBXN2A,KIAA0513,SRARP,SGIP1,STAG2,ZDHHC15,METTL21A,SESN3,RAB5B,SH3TC2,RPRD1A,PEX26,PALLD,TMCC1,THRA,TUBB2A,RPL7L1,ZFP37,ZNF708,LMAN2L" MicroRNA hsa-miR-4534:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-08 3.05E-04 7.59E-08 6.99E-07 31 205 "ANK1,SEMA7A,DOCK11,CAMK2A,CTNND1,SPATA2,EPS8,TUBA1B,TRAF3IP2,FAXC,TNRC6A,GLUL,RAB40B,KCND3,GPR155,OLA1,PKM,ZNF426,CEP97,SLC25A36,ELP2,HSD11B1L,SCN2B,ELMOD1,HSPA4L,NUBPL,FAM126B,KIAA0930,RPL7L1,ZNF708,KAT6A" MicroRNA hsa-miR-495-3p:Functional MTI Functional MTI miRTarbase 5.74E-08 3.23E-04 8.01E-08 7.38E-07 29 184 "MTA3,TMEFF1,MTMR9,KIAA1549L,BTF3L4,MYADM,DGKB,DLC1,HSP90AA1,C5orf24,IL6R,MSANTD3-TMEFF1,MEIS1,NCAM2,OCRL,PCMT1,ABCB1,TNPO2,CRLS1,PRRT2,ZNF354C,TRIM67,TAB2,SMOC1,LRRC4,MPRIP,ARL10,SF1,ADAMTS9" MicroRNA hsa-miR-572:mirSVR_highEffct hsa-miR-572:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.78E-08 3.25E-04 8.06E-08 7.42E-07 19 87 "PPFIA3,ARHGEF7,VSTM2A,TAOK2,BRD8,CCDC184,GRIA1,GRM1,CLASRP,ATXN2L,NCAM1,SNTG1,TMEM260,ATXN7,SMTN,SEPT8,DOCK9,SLC26A10,ANKS1B" MicroRNA hsa-miR-199a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.79E-08 3.25E-04 8.07E-08 7.43E-07 22 114 "QKI,COL4A5,LIN54,BLOC1S6,RGS17,ZNF585B,FLT1,GNAS,FICD,ZHX1,IGF1,CCDC80,PKM,MTRF1L,MAPK8,MAPK9,ATF7IP,TAB2,ZNF106,ZNF384,RGMB,WNK2" MicroRNA hsa-miR-4307:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.79E-08 3.25E-04 8.07E-08 7.43E-07 22 114 "CACNA1A,MYADM,DBN1,JAKMIP2,FEM1B,JKAMP,FYB1,GABRB1,TNRC6A,KCNMB4,IL1RAPL1,IBA57,NELL2,NEUROD2,OPCML,GDPD1,PEX26,PEG10,POGZ,RPL7L1,ZNF28,GAL3ST3" MicroRNA hsa-miR-483-5p:Functional MTI Functional MTI miRTarbase 5.83E-08 3.28E-04 8.13E-08 7.49E-07 25 143 "TAOK1,ALCAM,TRMT9B,API5,CBS,AKAP6,IGDCC3,HINFP,GNE,WDPCP,GFRA1,ZNF276,LAYN,NFIX,NUCB1,PDGFRA,MAPK3,ZNF793,ZYG11B,PRRT2,PEX26,TROVE2,ZNF384,ZNF708,ZNF70" MicroRNA hsa-miR-338-5p:Non-Functional MTI Non-Functional MTI miRTarbase 6.03E-08 3.38E-04 8.39E-08 7.73E-07 21 105 "XKR4,CAPRIN2,PTBP2,MATR3,GOLT1B,ABI2,GOLGA7,RCAN2,EFEMP1,CRCP,USP51,FIGN,TRA2B,NECAB1,CSMD1,UBE2H,VLDLR,TBC1D15,ZFP37,SMARCAD1,RTN4" MicroRNA hsa-miR-3691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.03E-08 3.38E-04 8.39E-08 7.73E-07 21 105 "ZBTB10,RGS6,DCAF8,ELMSAN1,SEC16A,EDIL3,CELSR3,EIF1,ANKFY1,TXNL4A,ATXN2L,KCNK3,AFF1,CCDC80,PDE1A,GTDC1,ATXN2,MPRIP,STAC2,TNS1,LAT2" MicroRNA hsa-miR-890:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.03E-08 3.38E-04 8.39E-08 7.73E-07 21 105 "AQP6,SLC16A4,FOXN3,CLU,UBXN2A,MYADM,CALN1,ABCC9,TMTC1,ZNF391,ZNF585B,GAP43,CECR2,SMAD9,PRKCB,KLHDC8A,LIMCH1,MCF2L2,SLC19A3,HPS4,SNX27" MicroRNA hsa-miR-3129-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-08 3.45E-04 8.54E-08 7.86E-07 15 55 "ARID1A,FZD9,JAZF1,NSL1,CLOCK,PYGO1,CHRDL1,ABI2,CAMSAP1,EPDR1,RBBP6,PBRM1,GSTCD,SYT4,SMARCAD1" MicroRNA hsa-miR-656-3p:Functional MTI Functional MTI miRTarbase 6.31E-08 3.54E-04 8.78E-08 8.09E-07 23 124 "BRAP,KIAA0408,SPATA2,KATNAL1,SYNCRIP,FYB1,BACH2,HSP90AA1,L1CAM,CCDC80,PDPK1,CCSER2,PEX2,FBXW7,FAM19A1,RAB3GAP1,AJAP1,TMEM178B,SIK3,HHIP,NR2C2,ZNF138,ZXDA" MicroRNA hsa-miR-4528:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.41E-08 3.60E-04 8.92E-08 8.22E-07 18 79 "MTA3,WDR35,PUM1,MFAP3L,KIAA1109,MSANTD4,GABRA4,TNRC6A,NR3C1,BVES,NEGR1,ZNF426,KANSL1,PBRM1,FNBP1,SOX11,TACC1,CLDND1" MicroRNA "ACAACCT,MIR-453:MSigDB" "ACAACCT,MIR-453:MSigDB" MSigDB 6.45E-08 3.62E-04 8.97E-08 8.26E-07 13 41 "CDK10,CDK13,NCOA1,FAM135B,PCDH8,FBXW7,ITSN1,PKNOX2,BTBD7,MBD5,TAL1,SNX27,LAS1L" MicroRNA hsa-miR-6855-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.72E-08 3.77E-04 9.34E-08 8.60E-07 25 144 "ADD1,C6orf89,BMP7,CACNG1,DIS3L,COL9A2,MICAL2,SOCS5,KIAA0586,PDLIM5,GLI2,TNRC6A,POLL,PRRC2B,ZNF491,GPR155,MDM4,PAK3,MAPK10,GDPD1,C12orf49,PTGR2,CLUAP1,PUM2,ZNF24" MicroRNA hsa-miR-663a:Functional MTI Functional MTI miRTarbase 6.72E-08 3.77E-04 9.34E-08 8.60E-07 25 144 "DPF1,PTCHD1,PDZD4,APC,PRX,ARHGDIA,EVI5L,ZNF385A,MICAL2,MYADM,EEF1A2,MTSS1L,NEUROD2,NRGN,PIK3CD,PACSIN1,C12orf49,PTGR2,SBF1,SLC1A2,PEX26,WBP2,VGF,ZNF154,NAV2" MicroRNA hsa-miR-3170:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.72E-08 3.77E-04 9.34E-08 8.60E-07 25 144 "ADD1,C6orf89,BMP7,CACNG1,DIS3L,COL9A2,MICAL2,SOCS5,KIAA0586,PDLIM5,GLI2,TNRC6A,POLL,PRRC2B,ZNF491,GPR155,MDM4,PAK3,MAPK10,GDPD1,C12orf49,PTGR2,CLUAP1,PUM2,ZNF24" MicroRNA hsa-miR-6806-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-08 3.78E-04 9.35E-08 8.62E-07 16 63 "SRSF11,SH3GLB1,ZBED3,NSG2,NR3C1,TLX1,SOWAHA,SYT9,SNX10,POLG,KANSL1,AMBRA1,RUFY2,RBFOX2,AMOT,MEAF6" MicroRNA hsa-miR-362-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-08 3.78E-04 9.35E-08 8.62E-07 16 63 "MTUS1,ASGR1,ZBTB10,CCNT1,LONRF2,SPATA2,NTM,ZNF585B,HHIPL1,FAXC,OS9,HSP90AA1,SLC35G1,KCNN3,RICTOR,LYPD6" MicroRNA hsa-miR-331-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-08 3.78E-04 9.35E-08 8.62E-07 16 63 "FAM135A,TNRC6C,E2F6,CELF1,IL6R,SLC35G1,LIFR,MDM4,MYCN,NAP1L1,SNX10,PPP1R1A,WLS,SAFB,BTBD3,AP4E1" MicroRNA hsa-miR-3928-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-08 3.78E-04 9.35E-08 8.62E-07 16 63 "SRSF11,SH3GLB1,ZBED3,NSG2,NR3C1,TLX1,SOWAHA,SYT9,SNX10,POLG,KANSL1,AMBRA1,RUFY2,RBFOX2,AMOT,MEAF6" MicroRNA hsa-miR-4639-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.74E-08 3.78E-04 9.35E-08 8.62E-07 16 63 "FZD9,CALM1,ELAVL2,UBE2E3,ZBED3,MAP4K5,ZNF678,KCNB1,PDPK1,PSAT1,FBXW7,SGK1,SLC6A8,NACC2,WNK1,SLC38A1" MicroRNA hsa-miR-124-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.78E-08 3.81E-04 9.41E-08 8.67E-07 17 71 "ACHE,TAOK1,SDC3,PLEKHA1,EN2,SUCO,UBE2E3,FOXG1,MAOB,PSAT1,SH3TC2,REV3L,RPH3A,ASTN2,NR2E1,LMAN2L,NELFE" MicroRNA hsa-miR-6801-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.94E-04 9.73E-08 8.96E-07 19 88 "XKR4,TRIM41,CLDN10,TOM1,MRO,ABI2,WAC,RAB40B,GPR26,MIER3,MAN2A2,NELL2,NFIX,NODAL,OPRL1,SCN7A,TMEM151B,NACC2,STOX2" MicroRNA hsa-miR-6810-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.94E-04 9.73E-08 8.96E-07 19 88 "XKR4,TRIM41,CLDN10,TOM1,MRO,ABI2,WAC,RAB40B,GPR26,MIER3,MAN2A2,NELL2,NFIX,NODAL,OPRL1,SCN7A,TMEM151B,NACC2,STOX2" MicroRNA hsa-miR-4513:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.94E-04 9.73E-08 8.96E-07 19 88 "ELFN2,KIAA0040,DBN1,MTX3,E2F6,MRNIP,FGF1,GRM3,DDR2,PDE4D,KCTD15,FAM126B,ZNF621,SMOC1,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-6855-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.94E-04 9.73E-08 8.96E-07 19 88 "ELFN2,KIAA0040,DBN1,MTX3,E2F6,MRNIP,FGF1,GRM3,DDR2,PDE4D,KCTD15,FAM126B,ZNF621,SMOC1,MPRIP,ZNF106,KAT6B,UPF3A,CADM2" MicroRNA hsa-miR-4272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-08 3.94E-04 9.73E-08 8.96E-07 19 88 "ADAR,ZNF608,ALAD,ACBD5,YTHDC1,FCF1,YAF2,ELAVL2,PLEKHA1,TNRC6A,NEGR1,IL6ST,PLCL1,PPP2R5E,SYT4,FBXL16,RBFOX2,ZNF28,WNK1" MicroRNA hsa-miR-637:Functional MTI Functional MTI miRTarbase 7.16E-08 4.02E-04 9.92E-08 9.14E-07 21 106 "TAOK1,PRX,ARHGDIA,BMP7,METTL6,NEURL1,ZNF385A,IP6K1,RASA4,KCNH2,CHST6,PKM,SBF1,GALNT10,CLSTN1,FNBP1,UNC5B,RAP1GAP2,USP22,CLASP1,RBFOX2" MicroRNA hsa-miR-769-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.34E-08 4.12E-04 1.02E-07 9.36E-07 27 165 "ACLY,EMILIN3,AP1B1,CD81,CLOCK,INTS1,POM121,PHF20L1,FUT10,GRIK2,STMN1,CHST6,MXI1,NME4,GPR137C,PLEC,MINDY2,GALNT10,LRRC55,FAM126B,PEG10,STAU1,NSD1,TIAM1,UBC,RPL7L1,ZFAND5" MicroRNA hsa-miR-378a-3p:Functional MTI Functional MTI miRTarbase 7.34E-08 4.12E-04 1.02E-07 9.36E-07 27 165 "ESYT2,DPY19L3,KSR1,MYRF,IGDCC3,E2F5,HIPK3,DCTN4,MRPL37,RTN3,ACSL4,CAB39,RNPS1,HSP90AA1,NME4,OCRL,CHAMP1,VPS13C,SLC22A23,FOXRED2,CASC3,TRA2B,SEC31A,STXBP1,ZBTB14,CELF4,WNK1" MicroRNA hsa-miR-3160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.54E-08 4.23E-04 1.04E-07 9.61E-07 30 197 "ZNF578,TRMT9B,FOXK1,CCPG1,ADGRG1,UBXN2A,NOS1AP,DNAL1,HP1BP3,EIF1,STX2,TUBB4A,FGFR1,RNPS1,CECR2,PLEC,FAT3,CEP97,ALG9,FNIP1,PEX26,SMARCE1,IQSEC2,LHPP,ACSBG1,FGD4,TMEM136,TPM4,TUBB2A,USP1" MicroRNA hsa-miR-1267:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.61E-08 4.28E-04 1.05E-07 9.71E-07 26 155 "ABCF1,AS3MT,ESYT2,ISPD,AKAP5,MRNIP,COQ7,SYNCRIP,LILRA2,SCIN,IBA57,GPR155,MKLN1,ZNF713,PDE3A,OLA1,RAVER2,ELP2,HSPA4L,ZFP30,PEX26,CPEB4,ANKRD36,ERC1,ZNF154,RNF170" MicroRNA hsa-miR-1304-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.66E-08 4.30E-04 1.06E-07 9.76E-07 24 135 "KLHL32,CEP126,LTBP4,CACNA1B,CCNT1,C1orf52,NRXN3,RIMS4,ABCC5,PCYOX1,GSN,KIF3A,ZNF491,KCND3,MMP17,PDE3A,A2ML1,MSANTD2,SLC2A5,NMNAT2,FAM208A,CBX5,TNS1,URM1" MicroRNA hsa-miR-6814-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.87E-08 4.42E-04 1.09E-07 1.00E-06 28 176 "AS3MT,RNF157,CDC14B,CACNA2D1,CSNK1E,UBXN2A,SH3GLB1,SLC43A2,ANKFY1,TRAF3IP2,KIF3A,RBPJ,SLC35G1,KCNH2,KCNK3,MBD1,CCDC80,PDE3A,EPB41L4B,PGBD4,SPIN3,ASAP3,TMCC1,KIF21B,MPRIP,KLHL7,ACSL6,LAT2" MicroRNA hsa-miR-26b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-08 4.49E-04 1.10E-07 1.02E-06 15 56 "SERPINA3,FOXK1,RCAN1,FEM1B,CACNG2,RNFT2,KCND3,LIFR,NCAM2,CRLS1,NCR3LG1,ZNF793,KCNIP3,PITPNB,SNX27" MicroRNA hsa-miR-3914:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-08 4.49E-04 1.10E-07 1.02E-06 15 56 "SLC24A4,CDC42,TMEM170A,DBN1,PLEKHM1,ZNF461,ADAM28,ARHGAP19,ITPKB,KIF5A,LAMP2,GPR137C,PKD1,SLC2A5,GAN" MicroRNA hsa-miR-555:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-08 4.49E-04 1.10E-07 1.02E-06 15 56 "CC2D2A,AQP6,CAPRIN2,CDR1,TVP23A,ZNF678,TTYH2,NAP1L1,KANSL1,ZFP30,AMBRA1,SON,SOX5,FAM168A,ZNF610" MicroRNA hsa-miR-4490:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-08 4.49E-04 1.10E-07 1.02E-06 15 56 "LONRF2,SLC24A2,BAG4,PHF19,KIT,MAT2A,EPDR1,PTPRE,C12orf49,SEMA6D,SMARCE1,TPD52,WBP2,NR2C2,WNK1" MicroRNA hsa-miR-5583-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-08 4.49E-04 1.10E-07 1.02E-06 15 56 "ARID1A,FZD9,JAZF1,NSL1,CLOCK,PYGO1,CHRDL1,ABI2,CAMSAP1,EPDR1,RBBP6,PBRM1,GSTCD,SYT4,SMARCAD1" MicroRNA hsa-miR-3607-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.46E-08 4.75E-04 1.17E-07 1.08E-06 17 72 "ABCF1,FMNL2,FOXK1,TMEM184B,PLEKHA1,ZNF585B,MED12L,IL6ST,SESN3,PPP2R5C,MCMBP,SOX5,PLCB1,SIN3B,DICER1,TNFRSF1B,ZNF24" MicroRNA hsa-miR-5100:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.46E-08 4.75E-04 1.17E-07 1.08E-06 17 72 "C1QTNF3,MATR3,EIF5,KATNAL1,SUCO,UFM1,CAMKK2,TNRC6A,ZBTB49,KCNN3,SESN3,PCSK1,EPB41L4B,MINDY2,SH3TC2,FGD4,SPATA13" MicroRNA hsa-miR-3174:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.48E-08 4.76E-04 1.17E-07 1.08E-06 21 107 "ASPH,CBR1,FOXN3,KIAA0040,MYADM,KIAA0513,MTX3,HMGB1,SCRG1,ZFYVE21,PLEC,KANSL1,NKAIN1,SH3TC2,RBBP8,RDX,TRA2B,SLC6A8,THRA,RBFOX2,TPM1" MicroRNA hsa-miR-6754-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.48E-08 4.76E-04 1.17E-07 1.08E-06 21 107 "DGKD,STOML1,PNKD,SUSD5,DOCK4,GAPVD1,CENPL,CALN1,NR1D2,STARD3NL,SRARP,DLC1,CELF1,KPNA5,SYTL4,TMOD2,SCN8A,ZC3H13,CYB561A3,ZNF138,ZNF195" MicroRNA hsa-miR-4711-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-08 4.78E-04 1.17E-07 1.08E-06 19 89 "PTCHD1,IGLON5,ST18,CHRDL1,FEM1B,KATNAL1,EFCAB2,CELF1,MMADHC,AP4S1,IGF1,KCNN3,MBNL1,SYT9,MITF,OLR1,NLGN3,ARHGEF9,ZDHHC20" MicroRNA hsa-miR-4670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-08 4.78E-04 1.17E-07 1.08E-06 19 89 "MTA3,INTS2,PTBP2,CANX,KIAA0513,MTHFD2,ATXN2L,NAT8L,BLOC1S2,SPATA6,MINDY2,TRA2B,FNDC3A,CPEB4,GPRIN3,ZKSCAN5,CLDND1,TFIP11,ZDHHC20" MicroRNA hsa-miR-5047:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.50E-08 4.78E-04 1.17E-07 1.08E-06 19 89 "SEMA6A,DST,CSNK1G3,PHF19,MAGI2,YAF2,FAM13A,CAB39,GLUL,KIAA1958,MBNL1,ZNF680,NBL1,ACER3,CPEB3,WBP2,RUNDC3B,RFTN2,WIPF2" MicroRNA hsa-miR-8065:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.56E-08 4.81E-04 1.18E-07 1.09E-06 16 64 "TAOK1,SLC22A6,SPATA2,DLC1,AMOTL2,TJAP1,BLOC1S2,PKD1,ZSCAN2,RAB5B,SETD5,SMARCE1,MAPK8IP3,TUBB2A,ZNF781,PRDM2" MicroRNA hsa-miR-1252-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.70E-08 4.88E-04 1.20E-07 1.11E-06 26 156 "STX16,TOGARAM2,OSBPL3,E2F6,MRVI1,CELF1,SALL3,TUBGCP4,COPS8,TNRC6A,GNAS,NUDT21,CIT,TJAP1,LIFR,MDM4,ZNF680,MYBPC1,NPTX1,CLDN11,CCSER2,EPB41L4B,TRA2B,SOX11,TUBB2A,CSDE1" MicroRNA hsa-miR-6514-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.88E-08 4.99E-04 1.23E-07 1.13E-06 25 146 "SEMA7A,BACH1,RUNX1T1,CCNT1,HECTD1,DNAL1,TRAF3IP2,GLUL,RAB40B,HSF2,GPR155,ZNF426,RAB5B,ELP2,SCN2B,ELMOD1,HSPA4L,SLITRK3,NUBPL,FAM126B,PEG10,ZC3H4,KIAA0930,ZFP91,ZNF708" MicroRNA hsa-miR-6877-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.39E-08 5.28E-04 1.30E-07 1.19E-06 22 117 "AP1M1,RIPOR2,ABI2,MRNIP,RGS17,FGF1,CELF1,DKK3,FAXC,SRCAP,NEGR1,PAK3,ZNF426,ZNF667,SNAP25,PEG10,ERBIN,KLHL7,VAMP1,TMEM151B,WNK1,CBLN2" MicroRNA hsa-miR-3944-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.39E-08 5.28E-04 1.30E-07 1.19E-06 22 117 "ST3GAL5,BSN,TBPL1,SPATA2,MAGI2,BLOC1S6,G3BP2,DYRK1A,ENPP6,AFF2,TNRC6A,MAT2A,MDM4,AFF1,MYBPC1,NBL1,RBBP6,CLIP1,NPAS3,MGRN1,NACC2,ZNF138" MicroRNA hsa-miR-4433b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.65E-08 5.42E-04 1.33E-07 1.23E-06 18 81 "SLC12A5,MTUS1,CA12,BRSK2,PITPNM3,SORBS3,NR3C1,SYNPO,KCNJ10,ZDHHC22,RDX,MAP6D1,GALNT10,SHANK2,SZT2,WBP2,VLDLR,ZNF24" MicroRNA hsa-miR-127-3p:mirSVR_highEffct hsa-miR-127-3p:mirSVR_conserved_highEffect-0.5 MicroRNA.org 9.65E-08 5.42E-04 1.33E-07 1.23E-06 18 81 "SYN3,ATP1A2,SEPT7,JAM2,GDA,EPHB1,AGAP3,AP4B1,ZNF496,TLX1,KCNK2,PKN2,MAPK4,BCAS3,PSMD13,SCN8A,FGD4,P2RY12" MicroRNA hsa-miR-5681a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-07 5.74E-04 1.41E-07 1.30E-06 24 137 "ARID1A,PHF12,FOXK1,TUBD1,SEMA4D,FUT10,C5orf24,TJAP1,SCAMP5,POU3F2,PXK,MSANTD2,INAVA,POGZ,ZSCAN29,ZMAT3,TPM3,RGMB,TUBB2A,UBC,MGAT5B,ZNF138,PRDM2,ITM2C" MicroRNA hsa-miR-6780b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-07 5.77E-04 1.41E-07 1.30E-06 19 90 "AQP6,CACNA1A,SLC16A4,SOCS5,SPATA2,WAC,LILRA2,KIF3A,TLX1,KLHL23,MEIS1,PHKG1,SH3TC2,MYO18A,BCAN,ZBTB43,PRRC2C,TMEFF2,ZDHHC20" MicroRNA hsa-miR-4662b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "SLC24A4,KIAA1614,ASPH,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,MAOB,CHST6,PPARA,TTLL7,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-4426:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "SLC24A4,KIAA1614,ASPH,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,MAOB,CHST6,PPARA,TTLL7,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-4647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "SLC24A4,KIAA1614,ASPH,DOCK11,LETMD1,CS,PYGO1,SCRN1,ZNF549,ZNF585B,FICD,KCNH2,MAOB,CHST6,PPARA,TTLL7,SLC25A36,ITPRID2,ZNF708,RTN4" MicroRNA hsa-miR-5685:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "ALDH4A1,KALRN,NEURL1,CS,DYRK1A,HEYL,EBI3,LYVE1,NCKAP1L,METTL21A,MMP17,VWA2,PDE2A,ZDHHC8,PIK3CD,PRRT2,IGSF9B,KIAA0930,TPM3,ZBTB16" MicroRNA hsa-let-7f-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "ZNF608,BACH1,C1orf52,COPB2,MYADM,RAB39B,GOLGA7,GABRG1,BRPF3,EML4,GRIK3,NCOA7,MBNL1,SESN3,KCNK10,KIF13A,DIP2A,GPRIN3,USP1,WNK1" MicroRNA hsa-miR-670-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-07 5.82E-04 1.42E-07 1.31E-06 20 99 "SEMA4G,ZNF385A,G3BP2,RCAN1,EIF5,TACC2,SEPT9,GRIK4,GPR45,NEGR1,SLC35G1,KCTD15,HMGCLL1,PROX1,DPF2,UBR7,GALNT10,TOM1L2,ZNF177,DHX33" MicroRNA hsa-miR-663b:PITA hsa-miR-663b:PITA_TOP PITA 1.08E-07 6.08E-04 1.49E-07 1.37E-06 16 65 "ASIC1,ADGRB1,SH2B1,EFNB3,NRN1,ACSL4,LRRC75A,MN1,GIT1,PDPK1,USP47,GTDC1,ATXN1,FAM214B,PUM2,TMEM198" MicroRNA hsa-miR-4420:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-07 6.08E-04 1.49E-07 1.37E-06 16 65 "ADARB2,INSYN2B,SLC2A11,LONRF2,SRSF11,CLTA,QKI,NSL1,ELMSAN1,ZIC4,GABRB1,GLUL,CNDP1,SLC37A2,FAM124A,RPL7L1" MicroRNA hsa-miR-3938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-07 6.08E-04 1.49E-07 1.37E-06 16 65 "OSBPL1A,AK2,LDHD,MYRF,CCDC144A,CEP78,GPR45,EID2B,ZNF793,SH3TC2,MYO18A,BCAN,ZCCHC24,TCF7L2,SEZ6L,NETO1" MicroRNA hsa-miR-545-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-07 6.18E-04 1.51E-07 1.39E-06 22 118 "APP,BAG4,LRIG1,GABRA2,KIF3A,ZIC5,ZNF678,DIPK1A,MID1,NAP1L1,NUCB1,ZNF426,CNTLN,SH3TC2,MCMBP,STX1B,PEG10,ITPRID2,FGD4,SLC44A1,MKRN3,WNK3" MicroRNA hsa-miR-887:PITA hsa-miR-887:PITA_TOP PITA 1.11E-07 6.21E-04 1.52E-07 1.40E-06 10 24 "ADD3,RNF150,ASTN1,ATP2B2,CCPG1,MAGI2,GAP43,NPTX1,SAFB,SCN8A" MicroRNA hsa-miR-4328:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.16E-07 6.50E-04 1.59E-07 1.46E-06 23 128 "GPAM,ZFYVE9,LONRF1,EDIL3,EDN1,ELAVL3,EIF1,RACK1,FOXO3,NPTN,IL6ST,CCDC80,PCSK2,PDE3A,PLCL1,TNPO2,FBXW7,CPEB3,NMNAT2,MPRIP,UNC5D,PPIL6,MEAF6" MicroRNA hsa-miR-4445-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.58E-04 1.61E-07 1.48E-06 14 50 "GREB1,PUM1,SEZ6,RAB30,RASSF8,NCKAP1L,HECTD2,MBNL1,MDM4,HS6ST3,PCMT1,ROBO1,ERC1,SATB2" MicroRNA hsa-miR-3141:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.58E-04 1.61E-07 1.48E-06 14 50 "ELFN2,BAIAP3,BRSK2,ELAVL3,MTSS1L,CPLX1,HMX1,JAKMIP3,NFIX,NRGN,OGDH,PEX26,ARC,FBXL16" MicroRNA hsa-miR-200c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-07 6.58E-04 1.61E-07 1.48E-06 14 50 "FEM1B,TUBD1,SYNCRIP,HSP90AA1,C2orf72,EFHB,MOG,SLC11A2,POLR2F,PKIA,ZYG11B,ZNF621,TPM3,HPS4" MicroRNA hsa-miR-100-5p:TargetScan hsa-miR-100-5p TargetScan 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "MTMR3,NIPBL,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,RAVER2,AP1AR,SATB1" MicroRNA hsa-miR-4724-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "ADD1,EIF4G3,DCAF8,TM9SF4,DPYSL2,ZNF589,KCNN3,KIF5C,ACER3,RXRA,RUFY2,ARHGAP9,HPS4" MicroRNA "CCTGAGT,MIR-510:MSigDB" "CCTGAGT,MIR-510:MSigDB" MSigDB 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "LRFN2,CAMK2G,ING4,EPHB1,IP6K2,GGT7,HLF,NOVA1,ZNF655,PPP2R5E,RORB,SF1,ST8SIA2" MicroRNA hsa-miR-99b-5p:TargetScan hsa-miR-99b-5p TargetScan 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "MTMR3,NIPBL,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,RAVER2,AP1AR,SATB1" MicroRNA hsa-miR-133a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "CCAR2,BAG4,PLEKHM1,DNAJB6,FEM1B,EGFR,FERMT2,GRID1,NR3C1,NEUROD1,ZNF426,C12orf49,MPPE1" MicroRNA hsa-miR-99a-5p:TargetScan hsa-miR-99a-5p TargetScan 1.22E-07 6.84E-04 1.67E-07 1.54E-06 13 43 "MTMR3,NIPBL,HS3ST2,FGFR3,INSM1,MBNL1,NTRK3,CLDN11,PPP3CA,EPDR1,RAVER2,AP1AR,SATB1" MicroRNA hsa-miR-6878-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-07 6.84E-04 1.67E-07 1.54E-06 27 169 "ZNF578,CEP126,TMEM263,ZNF582,MTMR9,FOXN3,COL9A2,TNRC6A,ZNF638,GNAL,HAS2,HMGB1,C2orf72,PIK3C2A,ZNF426,C12orf49,ZNF568,FOXRED2,DRAXIN,HSPA4L,CLUAP1,VAMP1,GPRIN3,ZNF34,CBX5,BCL2L13,ZNF70" MicroRNA hsa-miR-450a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-07 6.93E-04 1.69E-07 1.56E-06 20 100 "CACNB2,TPP1,HBS1L,SRCAP,GLI2,TNRC6A,PRRC2B,SCIN,MDM4,MSI1,NBL1,MAPK10,DRAXIN,COPZ1,NMNAT2,UNC5B,FAM168A,CBX5,MEAF6,CIAPIN1" MicroRNA hsa-miR-7850-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-07 6.93E-04 1.69E-07 1.56E-06 20 100 "TTYH1,ABAT,TEX22,OGT,UBXN2A,EN2,FAM184B,SRRM4,CNDP1,RNF165,ZIC5,KCNB1,MTRF1L,NKAIN1,GSTCD,MYO18A,FNDC3A,PARD3,ZNF384,PRDM10" MicroRNA "GCGCTTT,MIR-518D:MSigDB" "GCGCTTT,MIR-518D:MSigDB" MSigDB 1.25E-07 7.02E-04 1.71E-07 1.57E-06 9 19 "ZNF608,NRXN1,NSG2,SCRT2,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA "GCGCTTT,MIR-518C:MSigDB" "GCGCTTT,MIR-518C:MSigDB" MSigDB 1.25E-07 7.02E-04 1.71E-07 1.57E-06 9 19 "ZNF608,NRXN1,NSG2,SCRT2,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA hsa-miR-3684:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-07 7.02E-04 1.71E-07 1.57E-06 9 19 "QKI,POM121,PRRC2B,IFI16,KITLG,BTBD3,EXOC7,PUM2,CFAP298" MicroRNA "GCGCTTT,MIR-518B:MSigDB" "GCGCTTT,MIR-518B:MSigDB" MSigDB 1.25E-07 7.02E-04 1.71E-07 1.57E-06 9 19 "ZNF608,NRXN1,NSG2,SCRT2,SOX11,MCF2L,TSN,KCNK12,CELF4" MicroRNA hsa-miR-6819-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-07 7.22E-04 1.76E-07 1.62E-06 22 119 "AP1M1,RIPOR2,ABI2,MRNIP,RGS17,FGF1,CELF1,DKK3,FAXC,SRCAP,NEGR1,PAK3,ZNF426,ZNF667,SNAP25,PEG10,ERBIN,KLHL7,VAMP1,TMEM151B,WNK1,CBLN2" MicroRNA hsa-miR-502-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "NLGN4X,CA12,CDC27,ELAVL2,TOMM40L,DCTN2,MTHFD2,SESN1,AGBL5,IBA57,MSI1,PLEKHB2,PEG10,ZBTB43,SSTR1,PLCB1,LINC00632" MicroRNA hsa-miR-648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "SFMBT2,CALM1,EVI5L,RAB3C,SEC16A,EDN1,KATNAL1,MSANTD4,MALT1,HMGB1,XRRA1,QDPR,SGK1,MPRIP,MGRN1,ZFP91,ZNF138" MicroRNA hsa-miR-4682:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "RNF157,CPS1,PPP1R16B,SPATA2,RNF165,FICD,HMGB1,CLVS2,P2RX7,PDE4D,GRAMD1C,SLC25A36,SEMA6D,CHD9,FAM126B,ACSL6,NSD1" MicroRNA hsa-miR-5701:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "PHF12,DDO,SLC7A14,FOXK1,RUNX1T1,CDC27,KLHL3,ST8SIA3,TCERG1,LIX1,KCNJ10,MAT2A,ADAM22,PDE1B,DICER1,HEY2,ZNF711" MicroRNA hsa-miR-568:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "SLC7A14,ARRB1,ATP2A2,RUNX1T1,PUM1,EIF5,KATNAL1,MTHFD2,SRRM4,GCK,MIER3,C5orf24,JAK2,CLVS2,RUFY2,MPRIP,ACTR6" MicroRNA hsa-miR-502-5p:Functional MTI Functional MTI miRTarbase 1.30E-07 7.30E-04 1.78E-07 1.64E-06 17 74 "TNRC6C,CALM1,RAB3C,TPP1,TOMM20,KMT5B,ABI2,GJB1,HAS2,SHISA6,SHISAL1,NFYA,PRR5L,ATXN7,TRIM67,NACC2,SSPN" MicroRNA hsa-miR-148a-3p:Functional MTI Functional MTI miRTarbase 1.32E-07 7.41E-04 1.80E-07 1.66E-06 31 213 "ALCAM,TRMT9B,APC,STX16,MTMR9,CCKBR,CDC25B,QKI,DYRK1A,PAN3,NEURL4,TNRC6A,MSL3,RASSF8,HMGB1,HSP90AA1,ZIC5,SESN3,ZNF92,CNOT4,NPTX1,KANSL1,BTBD3,WDTC1,MYCBP2,CDK19,INKA2,DICER1,VAV2,PLPP4,FXR1" MicroRNA hsa-miR-34b-3p:Functional MTI Functional MTI miRTarbase 1.33E-07 7.46E-04 1.81E-07 1.67E-06 30 202 "AS3MT,SFMBT2,ZNF583,CDR1,KIAA1549L,IPCEF1,DNAL1,SGSM2,GNE,RBM12,MRNIP,SRARP,KBTBD12,GPR75,IL6R,SMAD9,MYCN,ABCB1,CEP97,CHD9,SEPHS1,SNCA,SOX2,CDK19,NXT2,USP22,AKNA,PCDHA6,ZBTB38,LMAN2L" MicroRNA hsa-miR-647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-07 7.46E-04 1.81E-07 1.67E-06 15 58 "SLC25A25,ANK2,NCOA1,CACNA1A,C1orf52,NIPBL,SV2B,MRVI1,SRRM4,ADAP1,NFIX,ZNF426,MAGI3,SLC1A7,ZNF610" MicroRNA "AGTCAGC,MIR-345:MSigDB" "AGTCAGC,MIR-345:MSigDB" MSigDB 1.33E-07 7.46E-04 1.81E-07 1.67E-06 15 58 "VAT1L,ATP2B3,CACNB2,CPEB2,EPS8,OGA,NFIA,PFKFB2,NXPH1,SCMH1,KIF1B,PRRC2C,SSBP2,UBE2H,SOCS4" MicroRNA hsa-miR-548k:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-07 7.50E-04 1.82E-07 1.68E-06 25 149 "MARCH4,BACH1,FOXK1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,KIF3A,HSP90AA1,IL6ST,KLRC3,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,CAMSAP2,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-8054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-07 7.50E-04 1.82E-07 1.68E-06 25 149 "MARCH4,BACH1,FOXK1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,KIF3A,HSP90AA1,IL6ST,KLRC3,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,CAMSAP2,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-548av-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-07 7.50E-04 1.82E-07 1.68E-06 25 149 "MARCH4,BACH1,FOXK1,CPS1,PYGO1,KATNAL1,MTHFD2,CRCP,KIF3A,HSP90AA1,IL6ST,KLRC3,MKLN1,ZFYVE21,REV3L,C12orf49,ALG9,ZBTB43,CEP68,CAMSAP2,NACC2,UBE2H,VSNL1,ZNF711,WNK3" MicroRNA hsa-miR-1249:mirSVR_highEffct hsa-miR-1249:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.36E-07 7.65E-04 1.85E-07 1.71E-06 16 66 "CDK10,CACNB2,RGN,KATNAL2,SGK2,HRASLS5,CACFD1,ING3,POU3F2,SCN8A,SNCA,SULF2,ICAM5,PRDM8,PHTF2,SLC4A10" MicroRNA hsa-miR-3152-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-07 7.65E-04 1.85E-07 1.71E-06 16 66 "CD81,CLU,PPP1R16B,DNAJB6,TRAF3IP2,CRCP,FICD,HMGB1,ZNF678,KCNN3,LAMP2,SESN3,DDR2,MAPK10,SETD5,ASTN2" MicroRNA hsa-miR-208a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-07 7.82E-04 1.90E-07 1.75E-06 21 110 "PCDH19,CDH2,LRIG1,SOCS5,SYNCRIP,UFM1,SRRM4,SLC2A6,RBPJ,SLC35G1,MTRF1L,PTAFR,CEP97,ATP8B4,KIF21A,SNAP25,SON,HEY2,LRRC8A,JMJD1C,ZDHHC20" MicroRNA hsa-miR-222-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-07 8.05E-04 1.95E-07 1.80E-06 18 83 "ADD1,COL4A5,ENTPD4,BLOC1S6,RGS17,ZNF585B,GABRA2,KITLG,GNG2,MTRF1L,CNTLN,RFX3,TAB2,STAU1,ZNF384,RGMB,MKRN3,WNK2" MicroRNA hsa-miR-339-3p:mirSVR_highEffct hsa-miR-339-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.43E-07 8.05E-04 1.95E-07 1.80E-06 18 83 "UNC79,CFLAR,PNKD,PDE4DIP,TMCC2,DNM1,IP6K2,CRCP,NR3C1,FAM19A2,NF1,GDAP1L1,SEC61A2,ARX,DDN,ADHFE1,VWA3A,PRMT8" MicroRNA hsa-miR-4418:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-07 8.23E-04 1.99E-07 1.84E-06 20 101 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,RAB5B,DRAXIN,RUFY2,BDP1,TCF7L2" MicroRNA hsa-miR-1471:mirSVR_lowEffct hsa-miR-1471:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.47E-07 8.23E-04 1.99E-07 1.84E-06 20 101 "METAP1D,CSF2RA,RHOBTB1,DLX1,SLC29A4,TOM1,EGFR,C3orf18,SRRM1,NRG3,SERP2,CACFD1,IGF1,KCNK1,KCNN3,MYO7A,FAM66C,ZSWIM8,PDLIM2,TSC1" MicroRNA hsa-miR-33b-5p:Functional MTI Functional MTI miRTarbase 1.47E-07 8.23E-04 1.99E-07 1.84E-06 20 101 "RNF157,KCTD16,SEMA7A,ZNF583,SOCS5,TMEM170A,EDN1,RTN3,ACSL4,FER,HBS1L,CNOT4,PSAT1,MAPK8,ATF7IP,ZNF415,PALLD,ZEB1,TNS1,REEP1" MicroRNA hsa-miR-6778-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-07 8.28E-04 2.00E-07 1.85E-06 29 192 "PHF12,LONRF2,SUMF2,CRY2,FAM131B,DCAF8,TOMM20,IP6K1,E2F6,PHC2,TMTC1,EFNA3,ABI2,AHDC1,NEGR1,KCNK3,NRGN,PDGFRA,PFKFB3,PMP22,PPARA,KLHDC8A,MRAS,SLC11A1,CAMTA2,RPRM,KLC2,CIAPIN1,WNK2" MicroRNA hsa-miR-346:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-07 8.34E-04 2.02E-07 1.86E-06 19 92 "CFLAR,BTK,CACNA1A,BSCL2,EZH1,PRMT5,FOXF2,GGT5,FAM107A,IL11RA,AFDN,SETD4,PDPK1,SBF1,STUM,ZCCHC24,USP22,HNRNPA3,GJC2" MicroRNA hsa-miR-4699-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.48E-07 8.34E-04 2.02E-07 1.86E-06 19 92 "GPR158,ABCD2,CSNK1G3,GOLT1B,HEYL,PRRC2B,NR3C1,ELOVL5,HMGB1,DOCK7,LOH12CR2,PTPRB,BTBD3,SLC8A1,SYT1,AGTPBP1,TRPS1,ZBTB16,FXR1" MicroRNA hsa-miR-1323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-07 8.42E-04 2.04E-07 1.88E-06 22 120 "ADCYAP1R1,MTMR9,ELMO1,MAMLD1,PLEKHA1,ZNF585B,CAMSAP1,EML4,HSP90AA1,SCIN,OPHN1,EPB41L4B,CRLS1,SGSM1,FNIP1,ATF7IP,UNC80,PEG10,ZMAT3,TUBB2A,PITPNB,MFF" MicroRNA hsa-miR-4294:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-07 8.75E-04 2.12E-07 1.95E-06 27 171 "MTA3,SEMA7A,APAF1,ISPD,AKAP5,RNF14,DNAL1,BSCL2,CAMKK2,CNDP1,LINC01551,C5orf24,NFIX,ZNF426,STRN3,ELP2,SCN2B,ELMOD1,HSPA4L,ZFP30,NUBPL,FAM126B,KIAA0930,ZNF106,TPM3,SF1,ZNF708" MicroRNA hsa-miR-571:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-07 9.00E-04 2.18E-07 2.00E-06 17 75 "MARCH4,CLU,CNTNAP2,PUM1,USP6NL,CELSR3,RABEPK,GLUL,FICD,HMGB1,NKAIN1,RAB5B,HSD11B1L,AMBRA1,TUBB2A,SF1,PMEPA1" MicroRNA hsa-miR-106a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-07 9.10E-04 2.20E-07 2.03E-06 28 182 "TRMT9B,SLC7A14,CANX,SCARB1,SPATA2,TIAM2,G3BP2,FKTN,CINP,GPR75,LILRA2,KAT7,HMGB1,MKLN1,SESN3,PDE3A,PLIN1,PIGG,ZNF532,PTGR2,SALL1,CDK19,SSTR2,DICER1,GPR161,RBFOX2,UBC,MFF" MicroRNA hsa-miR-26a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-07 9.53E-04 2.30E-07 2.12E-06 15 59 "INTS2,CEP126,ZBTB10,FER,AFF2,GABRB1,GABRG2,HBS1L,SYT17,SHISA6,FGFBP3,PKN2,FAM192A,CSRNP3,HNRNPA3" MicroRNA hsa-miR-488-5p:Functional MTI Functional MTI miRTarbase 1.70E-07 9.53E-04 2.30E-07 2.12E-06 15 59 "PHF19,SPATA2,RASGRP1,ELAVL4,TUBB4A,AFF2,IL6ST,KCTD15,ZNF426,PRKCB,NDUFS7,RXRA,CRB2,CSDE1,NELFE" MicroRNA hsa-miR-2277-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-07 9.53E-04 2.30E-07 2.12E-06 15 59 "SLC12A5,PRC1,TBPL1,CRY2,ING4,ANKMY1,CELF1,ATOH8,NODAL,PKD1,PRKACB,CNNM2,MGRN1,TLL2,UPF3A" MicroRNA hsa-miR-584-5p:Functional MTI Functional MTI miRTarbase 1.70E-07 9.57E-04 2.31E-07 2.13E-06 16 67 "TMEM263,USP6NL,TMEM170A,E2F5,DCTN4,STAMBP,FYN,SESN3,ZDHHC22,OLA1,ZNF655,SETD5,ZNF415,SON,CLDND1,ZNF195" MicroRNA hsa-miR-5008-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-07 9.75E-04 2.35E-07 2.17E-06 20 102 "GPRIN1,SLC24A4,TRMT9B,BTRC,CBARP,GREB1,SLC43A2,TMEM151A,RAB30,KIF3A,ZNF491,NUCB1,IQSEC3,BSDC1,KCNIP3,SLC8A3,MAPK8IP3,RPL7L1,INTS3,VANGL2" MicroRNA hsa-miR-4285:mirSVR_lowEffct hsa-miR-4285:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.74E-07 9.75E-04 2.35E-07 2.17E-06 20 102 "PTBP2,MFSD4A,DAPK3,BAIAP2,DISC1,COPS8,GRIA1,NUCB2,CEP41,MRPS18A,RPL15,SELL,ST3GAL3,SMARCA4,ACSBG1,ZC3H4,PDSS1,HIRA,ANKS1B,RGMA" MicroRNA hsa-miR-3118:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.74E-07 9.77E-04 2.36E-07 2.17E-06 18 84 "FMNL2,ELFN2,USP37,CA12,KIAA0040,RCAN1,MRNIP,TRMO,TJAP1,IL6ST,POLR2F,PEX26,FAM126B,ZNF621,SMOC1,ZNF106,KAT6B,UPF3A" MicroRNA hsa-miR-1180:mirSVR_highEffct hsa-miR-1180:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.74E-07 9.78E-04 2.36E-07 2.17E-06 25 151 "LRRC7,PARG,TNRC6C,TTLL9,ARHGEF7,SCAPER,CNIH3,FRY,HPCAL4,DACH2,AP4B1,MUM1,ZNF678,PCDH9,PCSK5,PDE3B,PPP2R5E,KANSL1,RASGRF2,BDP1,NUDT10,TPCN2,SEZ6L,PRDM2,ST7" MicroRNA hsa-miR-488-3p:Functional MTI Functional MTI miRTarbase 1.79E-07 1.01E-03 2.43E-07 2.24E-06 23 131 "ARID1A,BAG4,FAM169A,PITPNC1,SGIP1,FAXC,FUT10,GPR26,HAS2,TJAP1,PAX6,PXK,NAXD,INAVA,ZNF621,ERBIN,PCDHA6,ZMAT3,CBX5,TPM3,TUBB2A,UBC,PRDM2" MicroRNA hsa-miR-208a:PITA hsa-miR-208a:PITA_TOP PITA 1.81E-07 1.02E-03 2.45E-07 2.25E-06 11 31 "SYNJ1,IQCK,HDAC4,CPEB2,KLF12,MIER3,PPP2R5C,RYR3,CHD9,ARHGEF9,CADM1" MicroRNA hsa-miR-208b:PITA hsa-miR-208b:PITA_TOP PITA 1.81E-07 1.02E-03 2.45E-07 2.25E-06 11 31 "SYNJ1,IQCK,HDAC4,CPEB2,KLF12,MIER3,PPP2R5C,RYR3,CHD9,ARHGEF9,CADM1" MicroRNA hsa-miR-1238:PITA hsa-miR-1238:PITA_TOP PITA 1.81E-07 1.02E-03 2.45E-07 2.25E-06 11 31 "SLITRK1,APBB2,API5,ATP2B2,SYNJ1,LHX2,CSNK1G3,JAKMIP2,ZIC4,IL1RAPL1,CELF3" MicroRNA hsa-miR-383-5p:Functional MTI Functional MTI miRTarbase 1.92E-07 1.08E-03 2.60E-07 2.39E-06 21 112 "DIRAS1,ANKRD44,MRNIP,WAC,SUCO,SMC2,NCKAP1,GLUL,PCDH11X,ZIC5,SLC11A2,SLC22A23,SH3TC2,PEAR1,SFPQ,CLUAP1,TPM3,WBP2,TSN,ZFP37,GDPD5" MicroRNA hsa-miR-5006-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-07 1.10E-03 2.66E-07 2.45E-06 17 76 "ADD3,NOL4,CBS,BAG4,EXOG,KIAA1958,CAMKV,PIK3R1,TNPO2,PPARA,RPS6KA2,KIF21B,ZBTB43,SIN3B,ZNF28,CSDE1,PAK5" MicroRNA hsa-miR-106b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-07 1.10E-03 2.66E-07 2.45E-06 17 76 "MTMR3,CACNA1E,CBS,KMT2C,PLEKHM1,DPH1,CHST15,ZNF638,HNRNPK,LRP1B,NFE2L2,PCMT1,NUBPL,KDM4B,WNK1,PRDM2,UBE3B" MicroRNA "CTCCAAG,MIR-432:MSigDB" "CTCCAAG,MIR-432:MSigDB" MSigDB 1.97E-07 1.10E-03 2.66E-07 2.45E-06 17 76 "CAPN3,VXN,PITPNC1,CPEB2,STRADA,PDLIM5,EML4,GRIA2,PDE4A,PDE1B,PMP22,ANKRD28,PSD3,ZFP91,TRPC3,NSD2,TRIM9" MicroRNA hsa-miR-4777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.01E-07 1.13E-03 2.72E-07 2.50E-06 14 52 "FOXN3,BTF3L4,KIAA0408,FAM13A,FAXC,MALT1,KIAA1958,TLX1,LIMS1,POLR2F,ARMH4,WDR37,ITPRID2,EXOC7" MicroRNA hsa-miR-4742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.03E-07 1.14E-03 2.74E-07 2.52E-06 22 122 "GRAMD1B,SLC2A11,KLHL3,DCTN4,COQ7,SGIP1,SMC2,SRRM4,LILRA2,NEGR1,LSAMP,KANSL1,PRKCB,TMLHE,EPC1,UNC80,MYCBP2,FGD4,FAM208A,TLR4,CLDND1,ZFAND5" MicroRNA hsa-miR-3121-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.03E-07 1.14E-03 2.74E-07 2.52E-06 22 122 "KCTD16,SCARB1,BAG4,TOGARAM2,UBXN2A,RASSF2,ZNF585B,MAP4K5,CD200,SAMD5,GPR137C,PAX6,PDPK1,ZMAT4,SETD5,BTBD3,SLC6A8,UHRF1BP1L,ARHGAP26,NR2E1,HEY2,WIPF2" MicroRNA hsa-miR-509-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-07 1.15E-03 2.77E-07 2.55E-06 20 103 "ESYT2,PHF12,NUMB,SRSF11,ZBTB24,MTX3,TCERG1,GLUL,PADI2,BACH2,IL6R,IBA57,KCNH2,CYP27C1,MTRF1L,RAB5B,DRAXIN,RUFY2,BDP1,TCF7L2" MicroRNA hsa-miR-548v:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-07 1.15E-03 2.77E-07 2.55E-06 20 103 "RNF150,CDK5R1,CDC27,PITPNC1,STAMBP,RNPS1,TNRC6A,FICD,KCND3,TTC13,NWD1,SLC25A36,SETD5,STUM,ZFP1,TMCC1,TCF12,SLC19A3,CFAP298,CIAPIN1" MicroRNA hsa-miR-6784-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-07 1.18E-03 2.84E-07 2.61E-06 18 85 "RUNX1T1,JAKMIP2,C3orf18,AMOTL2,CELF1,GABRB3,GJB1,ELOVL5,HNRNPK,ZDHHC22,TMOD2,C12orf49,HUNK,AHCYL2,ZMAT3,ZNF781,ZNF195,MVB12B" MicroRNA hsa-miR-3119:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-07 1.18E-03 2.84E-07 2.61E-06 18 85 "ACTN2,CEP126,USP37,MARCH3,DST,THSD7A,ARHGAP32,AMOTL2,ZMAT1,NOVA2,NPTX1,DDR2,PDE3B,ATXN1,BTBD3,RBM26,CLASP1,LRP8" MicroRNA hsa-miR-4319:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-07 1.18E-03 2.84E-07 2.61E-06 18 85 "PLEKHG5,LONRF2,ZNF385A,TACC2,SMC2,CELF1,MUM1,NEGR1,SLC35G1,OPRL1,HMGCLL1,UBR7,COPZ1,TMEM136,ZNF177,DHX33,STOX2,TMEM63C" MicroRNA hsa-miR-653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-07 1.19E-03 2.87E-07 2.64E-06 16 68 "INSYN2B,SLC2A11,LONRF2,SRSF11,CLTA,NSL1,DBN1,ZIC4,GABRB1,GLUL,CNDP1,OPHN1,SEC31A,SEPHS1,KIAA0930,RPL7L1" MicroRNA hsa-miR-2861:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-07 1.19E-03 2.87E-07 2.64E-06 16 68 "GRAMD1B,APAF1,MYRF,CLU,NRG2,EGFR,MTSS1L,REEP2,NEU3,NKX2-2,BCAS3,MRPS18A,SHMT2,MAPK8IP3,ANKRD24,PARD3" MicroRNA hsa-miR-6733-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-07 1.19E-03 2.87E-07 2.64E-06 16 68 "KBTBD11,FEM1B,GCK,MKLN1,NUCB1,OPRL1,SLC25A36,KIAA0895L,ATXN1,SLC2A5,CXXC4,ITPRID2,PRRC2C,SATB2,CCDC14,ZNF24" MicroRNA hsa-miR-4715-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-07 1.26E-03 3.03E-07 2.79E-06 21 113 "ELFN2,SLC7A14,MARCH3,RNF14,HINFP,SPATA2,AASDH,TMTC1,CELF1,SLC2A6,RBPJ,MAN2A2,MTR,NOVA2,CAMKV,SH3TC2,ATF7IP,IGSF9B,RPL7L1,CFAP298,ZNF138" MicroRNA hsa-miR-3928-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-07 1.32E-03 3.17E-07 2.92E-06 22 123 "ELFN2,ASTN1,ALDH4A1,STX16,FMNL3,PLEKHM1,RAB39B,SYNCRIP,PTPRT,KIF3A,MIER3,SHISA6,ZFYVE27,DDR2,PDE3A,OXR1,KLHL11,DICER1,ZMAT3,RASD2,WRN,GAN" MicroRNA hsa-let-7a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.35E-07 1.32E-03 3.17E-07 2.92E-06 22 123 "SPAG9,C1orf52,MYOM2,COPB2,ARMC8,CS,MYADM,SEMA4D,GABRG1,BRPF3,ZNF181,ZNF546,NCOA7,MBNL1,SETD4,OCIAD1,CNKSR2,RUFY2,DIP2A,GPRIN3,WNK1,SENP7" MicroRNA hsa-miR-4493:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-07 1.35E-03 3.24E-07 2.98E-06 17 77 "TMCC3,ARHGDIA,CANX,CD81,AKAP5,IRAK3,PMP22,R3HDM2,MAPKBP1,SS18,MAPK8IP3,SATB2,VAV2,ZNF708,ZNF74,WNK2,NETO2" MicroRNA hsa-miR-548b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-07 1.35E-03 3.24E-07 2.98E-06 17 77 "ISPD,PRC1,CLCN3,KIAA0513,SPATA2,RCAN1,NBEA,PRRC2B,GPR26,GRIK4,AFF1,SALL1,SATB1,MYO16,VAMP1,TST,TFIP11" MicroRNA hsa-miR-4761-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-07 1.35E-03 3.24E-07 2.98E-06 17 77 "ABCF1,AS3MT,BRAP,ATP1B3,ARHGEF4,MRO,ANKFY1,FREM1,GNAL,MBD1,MDM4,CCSER2,RAB5B,TMCC1,SMOC1,TBL1X,FXR1" MicroRNA hsa-miR-523:mirSVR_lowEffct hsa-miR-523:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 2.53E-07 1.42E-03 3.40E-07 3.13E-06 19 95 "GRAMD1B,CAMK2A,KMT2C,SNX29,ADGRV1,ECSIT,IP6K2,GHR,MYT1,NELL2,PCSK5,PIK3CD,GPSM2,IRX1,ATAT1,RASA3,ST3GAL3,SLCO1A2,SNRPN" MicroRNA hsa-miR-4773:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.42E-03 3.40E-07 3.13E-06 19 95 "PHF12,MICAL2,SEC16A,FGF1,AFF2,CELF1,PTPRT,MDFI,MORC4,SETD5,ALG9,FNIP1,SNCB,GSE1,TMPRSS5,TUBB2A,GORASP1,FXR1,RNF146" MicroRNA hsa-miR-20b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.42E-03 3.40E-07 3.13E-06 19 95 "PTCHD1,SLC24A4,TXNDC16,PHF12,APAF1,MIER1,RASL11B,SLC16A4,HECTD1,AKAP12,SOCS5,DNAJB6,MTHFD2,IL6ST,N6AMT1,NPTX2,KSR2,TMEM178B,CBX5" MicroRNA hsa-miR-548g-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.42E-03 3.40E-07 3.13E-06 19 95 "BAG4,E2F6,STARD3NL,SCML2,SUCO,GFRA1,PACSIN2,ELOVL5,MXI1,DDR2,KANSL1,OCIAD1,ATXN1,GSE1,TMEM136,TLR4,PITPNB,ZFAND5,NHSL1" MicroRNA hsa-miR-3620-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.42E-03 3.40E-07 3.13E-06 19 95 "LRFN1,C6orf89,API5,APP,ZNF445,MTX3,AMOTL2,FOXF2,SMC2,FAXC,SRCAP,ELOVL5,SYNPO,KCNN3,PDE4A,PKD1,CLASP1,ZMAT3,GALNT17" MicroRNA hsa-miR-4714-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-07 1.42E-03 3.41E-07 3.14E-06 18 86 "ATP1A2,SEC31B,UBXN2A,SV2B,RABGAP1L,MRNIP,ENPP6,FOXO3,CRCP,NR3C1,LRRC75A,MBNL1,GPR137C,PLCL1,DRAXIN,LRRC55,BDP1,GAN" MicroRNA hsa-miR-432-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-07 1.48E-03 3.54E-07 3.26E-06 16 69 "FOXK1,ABI2,MRPL10,SRRM4,PCDH11X,GNAS,RAPGEF1,NXPH3,NUCB2,PKM,C1orf109,NKAIN1,POGZ,TMEM178B,RBFOX2,TSN" MicroRNA hsa-miR-520f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-07 1.48E-03 3.54E-07 3.26E-06 16 69 "ADD1,SORCS2,EFNA2,MRNIP,DKK3,DDR2,SPATA6,PLEKHB2,ZYG11B,SMARCE1,ZC3H13,CRTC1,DHX33,PPP1R3F,PLSCR4,NUP214" MicroRNA hsa-miR-6882-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-07 1.48E-03 3.54E-07 3.26E-06 16 69 "DST,TMEM170A,KLHL3,ELAVL3,MRVI1,TESK2,FER,SEPT9,RAPGEF1,ADAMTS8,MAP4,NFIX,PBX1,PDYN,KCTD15,NCBP3" MicroRNA hsa-miR-221-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-07 1.51E-03 3.60E-07 3.32E-06 24 144 "SMIM17,PDXK,ARHGDIA,DNAH17,BCL2L2,MTMR3,CCNT1,UFM1,ZNF234,HAS2,IL6R,KCNJ11,SEPT4,PTAFR,RPL15,SGSM1,RIMKLA,SLC1A7,KANSL3,SLC8A3,FNBP1,UNC5B,PRRC2C,ZNF70" MicroRNA hsa-miR-548an:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.72E-07 1.53E-03 3.66E-07 3.37E-06 22 124 "ZNF582,BTRC,CLCN3,HAPLN1,CDON,AMOTL2,ZMYND11,GSN,KAT7,C5orf24,AFF1,P2RY1,PSAT1,NCR3LG1,CPEB3,SYPL1,SATB2,RBFOX2,CADM1,TOM1L2,CLDND1,EVI5" MicroRNA hsa-miR-891a:PITA hsa-miR-891a:PITA_TOP PITA 2.73E-07 1.53E-03 3.66E-07 3.38E-06 10 26 "XKR4,TAOK1,CNR1,DAPK1,MBNL2,ELAVL3,SOX21,USP47,WDR47,MYT1L" MicroRNA hsa-miR-3074-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-07 1.60E-03 3.82E-07 3.52E-06 20 105 "ADD1,ABCD2,TNRC6C,PRX,ARSE,THSD7A,CDC27,LRRFIP1,IRAK4,DLC1,UFM1,PDLIM5,LILRA2,KPNA5,PBX1,MTRF1L,SP4,GANAB,EXOC7,ZNF138" MicroRNA hsa-miR-6505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-07 1.65E-03 3.93E-07 3.62E-06 17 78 "BBOX1,WASF1,SRSF11,RABEPK,STAMBP,BVES,KCNB1,MYBPC1,NCAM2,OPHN1,RETREG2,PPP2R5C,REV3L,PCMTD2,FNDC3A,STOX2,KAT6A" MicroRNA hsa-miR-3920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-07 1.65E-03 3.94E-07 3.63E-06 13 46 "XKR4,FOXN3,PUM1,SH3GLB1,FOXF2,RAB30,POLL,KCNN3,PPP3CB,ZCCHC24,DHX33,WNK3,DPF3" MicroRNA hsa-miR-6862-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-07 1.71E-03 4.08E-07 3.76E-06 18 87 "RUNX1T1,JAKMIP2,C3orf18,AMOTL2,CELF1,GABRB3,GJB1,ELOVL5,HNRNPK,ZDHHC22,TMOD2,C12orf49,HUNK,AHCYL2,ZMAT3,ZNF781,ZNF195,MVB12B" MicroRNA hsa-miR-8071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-07 1.71E-03 4.08E-07 3.76E-06 18 87 "TAOK1,NRXN3,TMEM184B,SIRPA,DUSP9,DYRK1A,MRPL10,ECSIT,MTHFD2,PPM1L,MKLN1,PLXNB1,PACSIN1,TNPO2,MYH14,GALNT10,STUM,PEG10" MicroRNA hsa-miR-3688-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-07 1.71E-03 4.09E-07 3.77E-06 21 115 "AK2,APP,FOXK1,RUNX1T1,CDC25B,CTNND1,G3BP2,EGR3,TUBA1B,SYNCRIP,ZBED3,DIPK1C,BVES,SAMD5,LRP12,ATXN1,HSPA4L,SLC6A8,ARL10,ZNF28,SLC38A1" MicroRNA hsa-miR-6510-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.05E-07 1.71E-03 4.09E-07 3.77E-06 21 115 "ARHGDIA,LDLRAD4,ABCC5,ELAVL3,DCTN4,FAM49B,RAPGEF1,PABPC1L2A,KCTD15,PACSIN1,SALL1,WDTC1,ERC1,ZC3H4,ASXL3,TPM3,TPM4,WBP2,BCL2L13,MEAF6,ITM2C" MicroRNA hsa-miR-320b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-07 1.72E-03 4.10E-07 3.78E-06 24 145 "ACLY,ADD1,SEMA7A,PHF12,TNRC6C,C2CD2,ATN1,EPB41,SYNCRIP,SRCAP,GLUL,GNAS,RBPJ,MKLN1,MAPK3,RTKN,HSPA4L,ATF7IP,ERC1,TAL1,SATB2,ARL10,TPD52,RNF103" MicroRNA hsa-miR-376a-5p:Functional MTI Functional MTI miRTarbase 3.26E-07 1.83E-03 4.36E-07 4.02E-06 16 70 "CDK13,COPB2,SRSF11,CLTC,FCF1,NUCB2,ZYG11B,ALG9,CHD9,SMARCE1,SOX11,SYNE2,USP22,DICER1,CSDE1,SPATA13" MicroRNA hsa-miR-5588-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-07 1.88E-03 4.48E-07 4.13E-06 20 106 "NCKAP5,PTCHD1,SLC24A4,TXNDC16,SEMA7A,APAF1,SLC16A4,ADGRG1,MTHFD2,BVES,RAB41,KLHL23,FGFBP3,MAOB,NDUFS7,ALG9,STAC2,CYB561A3,VWCE,CBX5" MicroRNA hsa-miR-6810-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-07 1.88E-03 4.48E-07 4.13E-06 20 106 "CACNB2,TPP1,TBPL1,HBS1L,SEPT9,SRCAP,SESN1,TNRC6A,TLX1,SCIN,MSI1,NBL1,PKM,POLR2F,DRAXIN,COPZ1,UNC5B,FAM168A,CBX5,CIAPIN1" MicroRNA hsa-miR-487a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-07 1.88E-03 4.48E-07 4.13E-06 14 54 "CLTC,ABCG2,MAGI2,MMP16,PIK3R1,KANSL1,FIGN,MCMBP,CPEB4,MYCBP2,SYPL1,INTS3,PMEPA1,ACTR3B" MicroRNA hsa-miR-7160-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-07 1.88E-03 4.48E-07 4.13E-06 14 54 "TXNDC16,LDLRAD4,APPL1,TOMM40L,CYP46A1,CSDC2,GNG3,CACFD1,NFIX,SFPQ,STX1A,GANAB,ANKRD24,NETO2" MicroRNA hsa-miR-4674:Functional MTI Functional MTI miRTarbase 3.35E-07 1.88E-03 4.48E-07 4.13E-06 14 54 "ARHGDIA,IPCEF1,RIPOR2,RUSC2,ZMAT1,ITPKB,NPTX1,HKR1,SETD5,DRAXIN,SLC6A8,BDP1,CLUAP1,TUBB2A" MicroRNA hsa-miR-1273g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.43E-07 1.93E-03 4.59E-07 4.23E-06 15 62 "BCL7A,CACNA1A,PTBP2,CD38,CREB5,RUBCN,DOCK4,RAB30,XRRA1,NWD1,GANAB,ZNF28,CIAPIN1,WIPF2,FXR1" MicroRNA hsa-miR-190b:Functional MTI Functional MTI miRTarbase 3.43E-07 1.93E-03 4.59E-07 4.23E-06 15 62 "ADCYAP1R1,ZNF608,SDC3,STAMBP,MSANTD4,HBS1L,RAB30,TNRC6A,KCNMB4,ADAMTS8,IGF1,IL6ST,TRA2B,BCL2L13,CSDE1" MicroRNA hsa-miR-374b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-07 2.00E-03 4.76E-07 4.38E-06 19 97 "TAOK1,SOCS5,CPEB2,FEM1B,TNRC6A,MBNL1,MKLN1,MAPK8,PTPRD,TMEM100,ZC3H14,SALL1,ATXN2,ZC3H13,KANK1,ACSBG1,ZMAT3,XKR7,PRDM10" MicroRNA hsa-miR-5584-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-07 2.00E-03 4.76E-07 4.38E-06 17 79 "C1orf52,SUSD5,UBXN2A,MTX3,SH3GLB1,AFF2,MTHFD2,FUT10,DOCK7,LSAMP,CCDC80,PNMA3,SLC30A10,MYO18A,SMOC1,ACSL6,TNS1" MicroRNA hsa-miR-6511b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-07 2.00E-03 4.76E-07 4.38E-06 17 79 "RUNX1T1,JAKMIP2,RCAN2,CELF1,MPP6,GABRA4,GGT7,ADAMTS13,HNRNPK,ZDHHC22,C12orf49,SNX22,HUNK,AJAP1,ZNF781,ZNF195,CERS6" MicroRNA hsa-miR-3129-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-07 2.00E-03 4.76E-07 4.38E-06 17 79 "QKI,COL4A5,LIN54,BLOC1S6,RGS17,ZNF585B,GNAS,FICD,CCDC80,PKM,MTRF1L,ATF7IP,TAB2,ZNF106,ZNF384,RGMB,WNK2" MicroRNA hsa-miR-658:PITA hsa-miR-658:PITA_TOP PITA 3.63E-07 2.04E-03 4.85E-07 4.46E-06 9 21 "LRFN1,CNTNAP1,CABP1,PPP1R16B,EEF1A2,SEMA6C,SCRT2,NRGN,DCBLD1" MicroRNA hsa-miR-1234:mirSVR_highEffct hsa-miR-1234:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.64E-07 2.05E-03 4.87E-07 4.48E-06 18 88 "SHTN1,RGS9,ENTPD4,CRMP1,PTK2B,MASP1,RPL15,ARMH4,SCN8A,TNFRSF19,FUZ,BTBD3,TTC17,WDTC1,ZC3H4,SYT4,EMSY,MPPE1" MicroRNA hsa-miR-548ao-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-07 2.05E-03 4.87E-07 4.48E-06 18 88 "JAZF1,CCNT1,BAG4,DBN1,MTX3,TAOK3,ZBED3,CRCP,MIER3,STMN1,MTR,PDE3A,OLA1,CSRNP3,HECW1,HHIP,SF1,CSDE1" MicroRNA hsa-miR-431-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.74E-07 2.10E-03 5.00E-07 4.60E-06 25 157 "CANX,ISPD,C1orf52,TBRG4,SOCS6,TBPL1,RTTN,SDC3,DBT,EFCAB2,ZBED3,FYN,SIGLEC8,SRRM4,SRCAP,GPR155,SESN3,ELMOD1,HSPA4L,FAM126B,KIF1B,KLHL7,FGD4,ACSL6,PCDHA6" MicroRNA hsa-miR-100:PITA hsa-miR-100:PITA_TOP PITA 3.76E-07 2.11E-03 5.02E-07 4.62E-06 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-99b:PITA hsa-miR-99b:PITA_TOP PITA 3.76E-07 2.11E-03 5.02E-07 4.62E-06 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-99a:PITA hsa-miR-99a:PITA_TOP PITA 3.76E-07 2.11E-03 5.02E-07 4.62E-06 11 33 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,CLDN11,PPP3CA,AP1AR,ST5,ANKRD28,SLC44A1" MicroRNA hsa-miR-8062:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.92E-07 2.20E-03 5.23E-07 4.81E-06 20 107 "MTA3,RTTN,RABGAP1L,PLEKHO1,FKTN,MSANTD4,FERMT2,KIF3A,RASSF8,EID2B,LYPLAL1,OCRL,NWD1,ROBO1,CSRNP3,SP2,AGTPBP1,SSBP2,RICTOR,WIPF2" MicroRNA hsa-miR-892b:Functional MTI Functional MTI miRTarbase 4.01E-07 2.25E-03 5.34E-07 4.92E-06 16 71 "TBC1D14,LDHD,CACNA1E,SEC24C,ABI2,KIAA1841,GRM5,MAPK8,MSANTD2,FNBP1,TCF7L2,NSD1,ZMAT3,ZNF384,ZNF24,RGMA" MicroRNA hsa-miR-4503:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-07 2.25E-03 5.34E-07 4.92E-06 16 71 "SPOP,VAT1L,CLTB,SLC25A27,IP6K1,GABRA5,LIMS1,SAMD5,SESN3,MYCN,PXK,ATXN1,MYT1L,PARD3,TPD52,C12orf4" MicroRNA hsa-miR-6512-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-07 2.25E-03 5.34E-07 4.92E-06 16 71 "ARID1A,TNRC6C,LDHD,ELMSAN1,SACS,ENPP6,KATNAL1,GUCY1A2,SAMD5,GPR137C,FIGN,HEY2,TRPS1,CADM1,ZNF711,ZNF189" MicroRNA hsa-miR-26a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-07 2.25E-03 5.34E-07 4.92E-06 16 71 "INTS2,CEP126,APAF1,ZBTB10,ACSL4,AFF2,GABRB1,GABRG2,SYT17,SHISA6,FGFBP3,PKN2,FAM192A,CSRNP3,TCF7L2,HNRNPA3" MicroRNA hsa-miR-184:PITA hsa-miR-184:PITA_TOP PITA 4.14E-07 2.32E-03 5.51E-07 5.08E-06 10 27 "EPB41L5,ADGRB2,TRIM41,SMG7,SIDT2,NTNG1,EPB41L3,MTCL1,ZFPM2,SF1" MicroRNA "TTCCGTT,MIR-191:MSigDB" "TTCCGTT,MIR-191:MSigDB" MSigDB 4.14E-07 2.32E-03 5.51E-07 5.08E-06 10 27 "ATP2B2,PHC2,NEURL4,GAP43,NRCAM,TMOD2,PLCD1,ZCCHC24,TJP1,MAP3K12" MicroRNA hsa-miR-4481:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-07 2.35E-03 5.57E-07 5.13E-06 22 127 "DNAH17,SEC24C,ZC3H11A,EFNA3,ING4,PNMA2,GLUL,MIER3,TJAP1,IBA57,PFKFB2,PKM,MRPS18A,KIAA0895L,NCBP3,SBF1,PEX26,TPCN2,SLC19A3,NSD1,RPRM,UBTF" MicroRNA hsa-miR-29a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-07 2.36E-03 5.59E-07 5.15E-06 19 98 "FOXN3,SLC24A2,HINFP,PUM1,HDAC9,SH3GLB1,RAB30,POLL,PTPRT,HLF,KCNN3,FAM98B,PPP3CB,NWD1,ZCCHC24,GANAB,DHX33,WNK3,DPF3" MicroRNA hsa-miR-4664-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-07 2.36E-03 5.59E-07 5.15E-06 19 98 "CRLF1,ZNF385A,MICAL2,IP6K1,PLEKHM1,ELN,GLI2,PRRC2B,MDM4,MPP2,EPN1,SPATA6,MAPK10,KLHDC8A,FOXRED2,ATXN2,NMNAT2,UBTF,VANGL2" MicroRNA hsa-miR-4291:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.20E-07 2.36E-03 5.59E-07 5.15E-06 19 98 "ELFN2,PDXK,RUBCN,MAML1,FEM1B,HEYL,FAM13A,EN2,FAM49B,NPTN,MTHFD2,DISC1,KCTD15,CPEB4,SLC37A2,TUBB2A,RPL7L1,ZNF45,GDPD5" MicroRNA hsa-miR-6772-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-07 2.41E-03 5.70E-07 5.25E-06 14 55 "RNF157,TBC1D14,NCOA1,CSNK1E,PLEKHO1,AMOTL2,SRRM4,POLL,HMX1,MN1,HMGCLL1,TNPO2,PRRC2C,WNK1" MicroRNA hsa-miR-5011-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-07 2.41E-03 5.70E-07 5.25E-06 14 55 "NLGN4X,SLC7A14,FOXN3,VCAN,PLXNA4,DNAL1,EIF1,CELF1,PCSK2,PDE3A,MPRIP,SSBP2,ZNF154,DHX33" MicroRNA hsa-miR-154-5p:Non-Functional MTI Non-Functional MTI miRTarbase 4.29E-07 2.41E-03 5.71E-07 5.26E-06 15 63 "FZD9,DNAL1,ZEB2,E2F5,WAC,SESN1,CIT,ZNF678,SNRK,RAB5B,SLC25A36,ZFP30,DICER1,CLDND1,ZXDA" MicroRNA hsa-miR-548o-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.77E-07 2.68E-03 6.35E-07 5.85E-06 21 118 "ADCYAP1R1,MTMR9,ELMO1,MAMLD1,PLEKHA1,ZNF585B,CAMSAP1,EML4,SCIN,OPHN1,EPB41L4B,CRLS1,SGSM1,FNIP1,ATF7IP,UNC80,PEG10,ZMAT3,TUBB2A,PITPNB,MFF" MicroRNA hsa-miR-4745-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.81E-07 2.70E-03 6.39E-07 5.89E-06 22 128 "DNAH17,SEC24C,ZC3H11A,EFNA3,ING4,PNMA2,GLUL,MIER3,TJAP1,IBA57,PFKFB2,PKM,MRPS18A,KIAA0895L,NCBP3,SBF1,PEX26,TPCN2,SLC19A3,NSD1,RPRM,UBTF" MicroRNA hsa-miR-4453:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.91E-07 2.76E-03 6.52E-07 6.01E-06 16 72 "SORCS2,PDXK,MTMR9,CALM1,CBS,FMNL3,EPB41,F3,PDLIM5,FAM98B,RAB5B,PGBD4,FBXO11,AJAP1,TUBB2A,XPO1" MicroRNA hsa-miR-4538:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.91E-07 2.76E-03 6.52E-07 6.01E-06 16 72 "SORCS2,PDXK,MTMR9,CALM1,CBS,FMNL3,EPB41,F3,PDLIM5,FAM98B,RAB5B,PGBD4,FBXO11,AJAP1,TUBB2A,XPO1" MicroRNA hsa-miR-542-5p:mirSVR_highEffct hsa-miR-542-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.95E-07 2.78E-03 6.58E-07 6.06E-06 19 99 "ARHGEF1,PPT2,SULT4A1,ZEB2,FDFT1,KBTBD12,TBR1,CLASRP,KCNJ11,MATK,FXYD7,ADHFE1,SYN1,RNF216P1,MTMR14,HSPBP1,AMOT,BEST1,NETO1" MicroRNA hsa-miR-2114-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.95E-07 2.78E-03 6.58E-07 6.06E-06 19 99 "ADCYAP1R1,PTCHD1,SLC24A4,TXNDC16,SEMA6A,APAF1,LDLRAD4,SLC16A4,ADGRG1,CELSR3,ANKFY1,MTHFD2,SRCAP,BVES,KLHL23,FGFBP3,MAOB,CBX5,WBP2" MicroRNA hsa-miR-548ax:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.18E-07 2.91E-03 6.88E-07 6.34E-06 18 90 "JAZF1,CCNT1,BAG4,DBN1,MTX3,TAOK3,ZBED3,CRCP,MIER3,STMN1,MTR,PDE3A,OLA1,CSRNP3,HECW1,HHIP,SF1,CSDE1" MicroRNA hsa-miR-633:Functional MTI Functional MTI miRTarbase 5.19E-07 2.92E-03 6.89E-07 6.35E-06 17 81 "SDE2,CACNG1,PRC1,CNN3,PREPL,CEP170,SH3GLB1,DLC1,ANKFY1,MMADHC,DDR2,LRP12,MAGI3,NAXD,SON,KANK1,ZDHHC20" MicroRNA hsa-miR-337-3p:Functional MTI Functional MTI miRTarbase 5.19E-07 2.92E-03 6.89E-07 6.35E-06 17 81 "MTA3,GAS7,RUNX1T1,CNN3,USP3,COQ7,ZDHHC15,IBA57,SESN3,BEST3,PKN2,MARCH1,ZFP30,ATP11A,TRPS1,RICTOR,FXR1" MicroRNA hsa-miR-103a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.19E-07 2.92E-03 6.89E-07 6.35E-06 17 81 "GPR146,MTMR7,RAB3C,ZNF585B,TMEM151A,GJB1,PTPRT,PTGDR2,IDH3B,LIFR,LSAMP,NODAL,PDE3A,MTRF1L,SLC22A23,CYB561D1,SNAP25" MicroRNA hsa-miR-190a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 5.34E-07 3.00E-03 7.08E-07 6.52E-06 15 64 "ADCYAP1R1,ZNF608,SDC3,STAMBP,MSANTD4,HBS1L,RAB30,TNRC6A,KCNMB4,ADAMTS8,IGF1,IL6ST,TRA2B,BCL2L13,CSDE1" MicroRNA hsa-miR-888-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.34E-07 3.00E-03 7.08E-07 6.52E-06 15 64 "INTS2,NOS1AP,KIAA0408,MTX3,ERBB2,AMOTL2,SESN1,RNPS1,GNAS,FICD,PKD1,SMOC1,DDHD1,UPF3A,CADM2" MicroRNA hsa-miR-544b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-07 3.06E-03 7.21E-07 6.64E-06 29 204 "ELFN2,RNF157,ASTN1,CCNT1,MYOM2,CDC25B,CPS1,SCML2,NCKAP1,SIGLEC8,LUZP2,LILRA2,HMGB1,ZDHHC15,METTL21A,CHIC1,MDM4,MMP17,SFR1,OPRL1,P2RX7,PIK3CD,ATXN2,PEX26,NEK4,ZNF106,TUBB2A,RPL7L1,LMAN2L" MicroRNA hsa-miR-3145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.45E-07 3.06E-03 7.22E-07 6.65E-06 14 56 "TAOK1,BTF3L4,TRAF3IP2,ELOVL5,NEGR1,L1CAM,ZNF680,ZYG11B,ATF7IP,SYP,PCDHA6,NDRG4,ZBTB16,GAN" MicroRNA hsa-miR-3200-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.45E-07 3.06E-03 7.22E-07 6.65E-06 14 56 "KLHL32,PPP1R16B,LONRF1,SPATA2,TNRC6A,CHIC1,NUCB2,GRAMD1C,SLC25A36,KANSL3,DDHD2,ZNF45,TFIP11,ZXDA" MicroRNA hsa-miR-302f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.52E-07 3.10E-03 7.32E-07 6.74E-06 31 227 "ABCF1,APAF1,ATM,PTBP2,SUMF2,PLCXD3,KIAA0513,DNAL1,HP1BP3,SEMA3D,RASA4,ZNF585B,ZNF589,NCKAP1,C5orf24,RBPJ,MXI1,PDE4D,ZNF844,ZDHHC14,ALG9,SNX22,ATXN1,MCF2L2,FGD4,PRRC2C,ZMAT3,ZNF154,WNK1,ZXDA,PARP11" MicroRNA hsa-miR-4308:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.83E-07 3.27E-03 7.72E-07 7.11E-06 19 100 "NIPA1,UBXN2A,IP6K1,ABCC5,ABI2,EIF5,IRAK4,ANKMY1,NSG2,CELF1,SEPT9,NCKAP1L,BEST3,MTMR10,RIMKLA,PEX26,DIP2A,EXOC7,KAT6A" MicroRNA hsa-miR-411-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-07 3.37E-03 7.93E-07 7.30E-06 16 73 "CCDC74A,ATP1B3,FSD1L,TUBD1,SCML2,MMADHC,C5orf24,SH3TC2,ALG9,PGBD4,FBXW7,SYPL1,TJP1,FAM182B,FXR1,NETO2" MicroRNA hsa-miR-7109-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-07 3.37E-03 7.93E-07 7.30E-06 16 73 "IGDCC4,CFL2,MRO,FGF1,TMEM179,SAMD5,PAK3,PKN2,UEVLD,SLC6A8,SMARCC2,TMEM151B,ZNF225,URM1,WIPF2,CBLN2" MicroRNA hsa-miR-8070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-07 3.37E-03 7.93E-07 7.30E-06 16 73 "INTS2,ATM,CD81,COPB2,DBN1,TOMM40L,TNRC6A,ADAP1,ZNF181,PROX1,UHRF1BP1,RNASEL,CLIP1,SON,TPCN2,PORCN" MicroRNA hsa-miR-4289:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-07 3.37E-03 7.93E-07 7.30E-06 16 73 "SEMA6A,MARCH4,LDHD,DLGAP3,C8orf37,GFRA1,UBE2QL1,HLF,PAX6,SMIM7,SALL1,CPEB4,SON,ZMAT3,ZNF106,MEAF6" MicroRNA hsa-miR-5591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-07 3.46E-03 8.14E-07 7.50E-06 18 91 "ELFN2,ADGRG1,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,PTPA,LHFPL4,ERC1,NFASC,CAMTA2,APOM,TPD52L2,PPIL6,RPRM,VAV2" MicroRNA hsa-miR-6715b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-07 3.46E-03 8.14E-07 7.50E-06 18 91 "CPNE5,ZBTB10,YTHDC1,KLHL3,FEM1B,FCF1,TNRC6A,CIT,PTGDR2,SLC35G1,MXI1,KSR2,PTPRN2,CSRNP3,TRA2B,ASXL3,TPM3,SF1" MicroRNA hsa-miR-6726-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-07 3.46E-03 8.14E-07 7.50E-06 18 91 "ELFN2,ADGRG1,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,PTPA,LHFPL4,ERC1,NFASC,CAMTA2,APOM,TPD52L2,PPIL6,RPRM,VAV2" MicroRNA hsa-miR-920:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.16E-07 3.46E-03 8.14E-07 7.50E-06 18 91 "ELFN2,ADGRG1,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,PTPA,LHFPL4,ERC1,NFASC,CAMTA2,APOM,TPD52L2,PPIL6,RPRM,VAV2" MicroRNA hsa-miR-6871-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.22E-07 3.49E-03 8.22E-07 7.57E-06 20 110 "ADAR,ELFN2,DDX3Y,BACH1,BTRC,NCOR2,SPATA2,SPECC1,NCKAP1,KCNB1,NPTX2,GPR137C,SDK2,KANSL1,PTPRE,SETD5,KIAA0895L,PEX26,TPCN2,UBTF" MicroRNA hsa-miR-6875-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.22E-07 3.49E-03 8.22E-07 7.57E-06 20 110 "ELFN2,ZNF385A,ENTPD4,TRAPPC9,DNM2,EIF4G1,MTSS1L,HBS1L,GSN,NDUFA5,TNPO2,NCR3LG1,MORC4,MYO18A,CAMTA2,SMOC1,NACC2,TPM2,TUBB2A,PMEPA1" MicroRNA hsa-miR-642a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-07 3.51E-03 8.24E-07 7.59E-06 17 82 "CACNA1B,CDC25B,FOXN3,KIAA0408,MTX3,EXOG,SYNCRIP,SGIP1,HMGB1,MPP2,PDE4D,OXR1,PNMA8A,NCBP3,PPP4R3A,USP22,BHLHB9" MicroRNA hsa-miR-199b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-07 3.51E-03 8.24E-07 7.59E-06 17 82 "QKI,COL4A5,LIN54,BLOC1S6,RGS17,ZNF585B,GNAS,FICD,CCDC80,PKM,MTRF1L,ATF7IP,TAB2,ZNF106,ZNF384,RGMB,WNK2" MicroRNA hsa-miR-642b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-07 3.51E-03 8.24E-07 7.59E-06 17 82 "CACNA1B,CDC25B,FOXN3,KIAA0408,MTX3,EXOG,SYNCRIP,SGIP1,HMGB1,MPP2,PDE4D,OXR1,PNMA8A,NCBP3,PPP4R3A,USP22,BHLHB9" MicroRNA hsa-miR-6798-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.38E-07 3.58E-03 8.42E-07 7.75E-06 21 120 "NDRG3,RNF157,PNMA8B,SYT13,KIF6,NCOR2,EIF4G1,WAC,CELF1,GFER,RAPGEF1,HMGB1,SESN3,TNPO2,NCR3LG1,MYH14,SARS,NFASC,ZFP91,UBTF,ITM2C" MicroRNA "GCTGAGT,MIR-512-5P:MSigDB" "GCTGAGT,MIR-512-5P:MSigDB" MSigDB 6.57E-07 3.69E-03 8.67E-07 7.98E-06 13 49 "DLGAP2,CHRM1,PLEKHM1,EMX2,SOX21,KCNA6,NFIX,PIK3R1,PRIMA1,COPZ1,CHD9,SRPK2,FBXW11" MicroRNA hsa-miR-598:PITA hsa-miR-598:PITA_TOP PITA 6.57E-07 3.69E-03 8.67E-07 7.98E-06 13 49 "ARID1A,B3GALT2,CALM1,CHD5,ZEB2,TOX3,MN1,PTPRZ1,ZDHHC14,SNCA,WDR7,TIAM1,ZFP91" MicroRNA "GTAAACC,MIR-299-5P:MSigDB" "GTAAACC,MIR-299-5P:MSigDB" MSigDB 6.57E-07 3.69E-03 8.67E-07 7.98E-06 13 49 "ABR,PHF12,CS,HDAC4,CPEB2,FOXG1,CAB39,MAT2A,MDGA2,ROBO1,SGK1,PUM2,NAV3" MicroRNA hsa-miR-4450:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-07 3.72E-03 8.73E-07 8.04E-06 15 65 "PPFIA4,ARRB2,CACNB2,KLHL3,TMCC2,APH1A,DLC1,KCNN3,SLC25A23,BTBD3,MPRIP,ACSBG1,CLIP2,LAT2,CIAPIN1" MicroRNA hsa-miR-4318:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-07 3.72E-03 8.73E-07 8.04E-06 15 65 "SDE2,ADCY2,BRAP,TRMT9B,LONRF2,PYGO1,AP4S1,RBPJ,LIMS1,MBNL1,MMP16,TNPO2,PEX2,ALG9,ELP2" MicroRNA hsa-miR-6764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.70E-07 3.76E-03 8.83E-07 8.13E-06 31 229 "NDRG3,PTCHD1,MTA3,MARCH4,FOXK1,TMEM184B,RTTN,RNF14,FGFR1OP2,IP6K1,ELMSAN1,GNE,CNNM1,HEYL,EIF4G1,CELF1,NSG1,MSANTD4,GJB1,CRCP,KIAA1958,KIF3A,BACH2,NKD1,IL6R,FAM216A,ZNF844,RGS12,ACSL6,ERCC6L2,TSPAN11" MicroRNA hsa-miR-548u:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-07 3.84E-03 9.01E-07 8.29E-06 19 101 "ZNF608,TRMT9B,SFMBT2,LDHD,CACNB2,BAG4,CNTNAP2,KATNAL1,PACSIN2,HMGB1,ZNF678,AFF1,MN1,PROX1,TCP11L1,YPEL4,EPB41L3,TSC1,CLDND1" MicroRNA hsa-miR-6781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-07 3.84E-03 9.01E-07 8.29E-06 19 101 "RNF150,ARSE,AP1M1,ELMSAN1,DYRK1A,FLYWCH1,DKK3,FAXC,NXPH3,KCNJ9,ATXN2,LRRC55,ZNF621,VAMP1,TMEM151B,CBX5,WNK1,LINC00632,HNRNPA3" MicroRNA hsa-miR-1206:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-07 3.84E-03 9.01E-07 8.29E-06 19 101 "SORCS2,TAOK1,CDC14B,TOGARAM2,RNF14,KIAA0408,PLEKHA1,C8orf37,FOXG1,CRCP,SAMD14,MYBPC1,GPR137C,ZSCAN2,ATXN1,ACSL6,NR2E1,UBE3A,NSD2" MicroRNA hsa-miR-6812-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-07 3.84E-03 9.01E-07 8.29E-06 19 101 "CRLF1,ZNF385A,MICAL2,IP6K1,PLEKHM1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MDM4,MPP2,EPN1,SPATA6,MAPK10,KLHDC8A,FOXRED2,ATXN2,UBTF" MicroRNA hsa-miR-2682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.84E-07 3.84E-03 9.01E-07 8.29E-06 19 101 "RNF150,ARSE,AP1M1,ELMSAN1,DYRK1A,FLYWCH1,DKK3,FAXC,NXPH3,KCNJ9,ATXN2,LRRC55,ZNF621,VAMP1,TMEM151B,CBX5,WNK1,LINC00632,HNRNPA3" MicroRNA "AGCGCTT,MIR-518E:MSigDB" "AGCGCTT,MIR-518E:MSigDB" MSigDB 6.86E-07 3.85E-03 9.03E-07 8.32E-06 8 17 "ZNF608,CAPN3,NRXN1,ZNF385A,EGR3,NSG2,SON,MCF2L" MicroRNA hsa-miR-1537-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.86E-07 3.85E-03 9.03E-07 8.32E-06 8 17 "FOXK1,FMNL3,PLEKHM1,IL6R,INPP5B,SLC11A2,NUCB1,ZDHHC20" MicroRNA "AGCGCTT,MIR-518F:MSigDB" "AGCGCTT,MIR-518F:MSigDB" MSigDB 6.86E-07 3.85E-03 9.03E-07 8.32E-06 8 17 "ZNF608,CAPN3,NRXN1,ZNF385A,EGR3,NSG2,SON,MCF2L" MicroRNA "AGCGCTT,MIR-518A:MSigDB" "AGCGCTT,MIR-518A:MSigDB" MSigDB 6.86E-07 3.85E-03 9.03E-07 8.32E-06 8 17 "ZNF608,CAPN3,NRXN1,ZNF385A,EGR3,NSG2,SON,MCF2L" MicroRNA hsa-miR-581:Functional MTI Functional MTI miRTarbase 6.88E-07 3.87E-03 9.05E-07 8.34E-06 14 57 "SPAG9,RUNX1T1,SLC22A6,PPP1R16B,SPATA2,G3BP2,TACC2,KNDC1,SESN3,NTRK2,PURG,SATB1,DICER1,HNRNPA3" MicroRNA hsa-miR-891b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-07 3.87E-03 9.05E-07 8.34E-06 14 57 "MTX3,SYNCRIP,HHIPL1,CNDP1,HMGB1,IBA57,PTPRD,SALL1,PEX26,DIP2A,TCF7L2,ZNF106,CSDE1,WNK3" MicroRNA hsa-miR-17-3p:Functional MTI Functional MTI miRTarbase 6.99E-07 3.93E-03 9.19E-07 8.46E-06 26 173 "TXNDC16,SFMBT2,DNAH17,STX16,MYRF,FOXK1,P2RX6,IP6K1,DCC,OPTN,SRCAP,ATOH8,MDM4,NACA,ENPP2,PKM,GPSM2,PLCD1,ELOVL2,TRIM68,SMARCE1,ZNF423,HIRA,UBE2H,XPO1,SF1" MicroRNA hsa-miR-4766-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.25E-07 4.07E-03 9.52E-07 8.77E-06 22 131 "SEMA7A,RTTN,AKAP12,RAB39B,KATNAL1,POLR1B,FAXC,ZNF680,THYN1,CEP97,SH3TC2,ALG9,SLC8A1,SON,SOX5,ITPRID2,DDHD2,ZMAT3,RUNDC3B,PLEKHH2,CADM2,WIPF2" MicroRNA hsa-miR-4763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.29E-07 4.09E-03 9.57E-07 8.82E-06 16 74 "TAOK1,USP37,ARHGDIA,ARSE,CFAP410,RNF14,IP6K1,VTI1B,GJB1,CRCP,RAPGEF1,ATCAY,HSPA4L,SIN3B,GPRIN3,CFAP298" MicroRNA hsa-miR-125b-1*:mirSVR_highEffct hsa-miR-125b-1*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 7.29E-07 4.09E-03 9.57E-07 8.82E-06 16 74 "NDRG2,TXNDC16,BCAS1,CNTN1,USP6NL,MATR3,GAP43,DNER,SRCAP,RASSF8,NCOA7,MARK1,NF1,PIRT,MDGA2,RPH3A" MicroRNA hsa-miR-4300:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.29E-07 4.10E-03 9.58E-07 8.82E-06 18 92 "ELFN2,ADGRG1,E2F6,ANKFY1,NEGR1,NBL1,NPTX2,PKD1,PTPA,LHFPL4,ERC1,NFASC,CAMTA2,APOM,TPD52L2,PPIL6,RPRM,VAV2" MicroRNA hsa-miR-4780:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.29E-07 4.10E-03 9.58E-07 8.82E-06 18 92 "AQP6,CACNA1A,SLC16A4,SPATA2,LILRA2,KIF3A,TLX1,KLHL23,MEIS1,PHKG1,SH3TC2,MYO18A,BCAN,ZBTB43,PRRC2C,TAL1,TMEFF2,ZDHHC20" MicroRNA hsa-miR-3157-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.35E-07 4.13E-03 9.65E-07 8.89E-06 21 121 "SDE2,SORCS2,PCDHGB4,SLC2A11,HINFP,EXOG,DYRK1A,WDPCP,TMTC1,MRO,LYVE1,POLL,DIDO1,PTAFR,RDX,HUNK,ZFP30,SNAP25,DIP2A,ZNF711,GAN" MicroRNA hsa-miR-3655:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.36E-07 4.14E-03 9.66E-07 8.90E-06 12 42 "XKR4,SOCS5,FEM1B,HEYL,GPR75,KCNJ10,PIGG,PTGR2,GALNT10,WDR37,FAIM2,ZNF28" MicroRNA hsa-miR-218-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.36E-07 4.14E-03 9.66E-07 8.90E-06 12 42 "PCDHGB4,MAP7,CD38,PHF19,IRAK4,FER,P2RX7,PIK3C2A,PIK3R1,ZNF426,RPL15,KLHL7" MicroRNA hsa-miR-6728-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.48E-07 4.20E-03 9.81E-07 9.04E-06 17 83 "BACH1,CDC25B,CLOCK,SEC24C,DCAF8,DNAL1,GLUL,PRRC2B,GRIK2,STMN1,CHST6,MINDY2,STX1B,GALNT10,LRRC55,STAU1,NSD1" MicroRNA hsa-miR-135b-5p:Functional MTI Functional MTI miRTarbase 7.48E-07 4.20E-03 9.81E-07 9.04E-06 17 83 "KIF6,APC,CDR1,HEYL,AMOTL2,KIAA1958,MBNL1,MEF2C,MID1,TNPO2,PPP2R5C,PEX2,TTLL7,PPM1E,ARC,SLC19A3,EVI5" MicroRNA hsa-miR-558:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-07 4.29E-03 1.00E-06 9.23E-06 28 196 "ELFN2,ZNF578,TRMT9B,FOXK1,CCPG1,EPS15L1,AATK,UBXN2A,DNAL1,HP1BP3,FAM13A,STX2,FGFR1,RNPS1,GSN,PLEC,FAT3,CEP97,ALG9,FNIP1,HES6,PEX26,SMARCE1,LHPP,ACSBG1,FGD4,TPD52L2,USP1" MicroRNA hsa-miR-4786-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.70E-07 4.33E-03 1.01E-06 9.30E-06 34 266 "GRAMD1B,SMIM17,APP,PDXK,DOCK11,CCNT1,NRXN3,CTH,USP6NL,KIAA0513,YTHDC1,PLEKHM1,MRO,SCARA3,AFF2,KIAA1841,LUZP2,MAG,MMP17,SFR1,ZDHHC8,PIK3CD,CCSER2,BDNF-AS,PEX2,CEP97,KLHL11,MAGI3,URGCP,PEX26,RAB3GAP1,SLC37A2,AHCYL2,TBC1D15" MicroRNA hsa-miR-4708-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.92E-07 4.45E-03 1.04E-06 9.56E-06 23 142 "MTA3,CDC25B,JAKMIP2,PLEKHA1,C1orf61,NCKAP1,FAXC,GLUL,SHISA6,KCNJ3,NOS1,ZNF426,PPP2R5E,ELP2,SCN2B,ELMOD1,FAM102A,NUBPL,TAB2,KIAA0930,TUBB2A,ZNF708,STOX2" MicroRNA hsa-miR-6737-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.01E-07 4.50E-03 1.05E-06 9.66E-06 19 102 "CRLF1,ZNF385A,MICAL2,IP6K1,PLEKHM1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MDM4,MPP2,EPN1,SPATA6,MAPK10,KLHDC8A,FOXRED2,ATXN2,UBTF" MicroRNA hsa-miR-657:Functional MTI Functional MTI miRTarbase 8.01E-07 4.50E-03 1.05E-06 9.66E-06 19 102 "TBPL1,PITPNC1,DPYSL2,ENPP6,CELF1,SLC2A6,GPR155,ATXN1,SCN4B,PEX26,SEPHS1,MAPKBP1,TMCC1,ZSCAN29,GPRIN3,KCTD2,TPD52L2,EMSY,XKR7" MicroRNA hsa-miR-3614-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.16E-07 4.59E-03 1.07E-06 9.85E-06 15 66 "ADD1,PDE4DIP,PPP1R16B,FAM131B,CDON,TXNL4A,LIFR,CHST6,NPTX2,NUCB1,GPR137C,PDE3A,BDP1,ANKRD28,TPM3" MicroRNA hsa-miR-7108-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.16E-07 4.59E-03 1.07E-06 9.85E-06 15 66 "ELFN2,CARNS1,CFAP410,CRY2,SOCS5,IL1RAPL1,SCRT2,ZNF678,MPP2,ALDH1L2,MRPS18A,ZNF331,KIF21B,DDN,TBCEL" MicroRNA hsa-miR-3065-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.38E-07 4.71E-03 1.10E-06 1.01E-05 20 112 "STX16,CDC25B,TOGARAM2,PPP1R16B,RIMS2,ING4,C2orf72,KCNN1,ENPP2,GPSM2,CEP97,MAPKBP1,ZC3H4,SLC37A2,CLASP1,CBX5,TUBB2A,ZNF45,TMEM237,URM1" MicroRNA hsa-miR-5694:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.45E-07 4.75E-03 1.11E-06 1.02E-05 21 122 "HECW2,HACE1,AQP6,CBR1,CBFA2T2,ZNF385A,TMEM170A,MRNIP,PCDH11X,MSL1,SLC11A2,FAT3,STK32A,ZNF844,SH3TC2,FBXW7,SFPQ,FAM208A,ZNF610,RPL7L1,ZFP37" MicroRNA hsa-miR-553:PITA hsa-miR-553:PITA_TOP PITA 8.47E-07 4.76E-03 1.11E-06 1.02E-05 13 50 "SLC12A5,ARHGAP5,C2CD2L,ZIC4,FOXO3,PPP2R2B,AMER2,UNC5D,CUX2,NR2C2,RPRM,ZBTB14,PHTF2" MicroRNA hsa-miR-4803:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.62E-07 4.84E-03 1.13E-06 1.04E-05 18 93 "GOLGA7B,EPS15L1,BAG4,CEP170,SV2B,EFHB,NAP1L1,PRKAB2,MAPK7,ZYG11B,SLC25A36,SGK1,SS18,TMEM178B,TLL2,TUBB2A,UBE2H,ZNF711" MicroRNA hsa-miR-3143:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.62E-07 4.84E-03 1.13E-06 1.04E-05 18 93 "ADD1,AMPD3,BACH1,GAPVD1,MATR3,FAM13A,SESN3,SPDL1,ZYG11B,STX1B,SATB1,SHC4,FNDC3A,UBE2H,ZNF711,ZBTB38,EML6,CSDE1" MicroRNA "CAAGGAT,MIR-362:MSigDB" "CAAGGAT,MIR-362:MSigDB" MSigDB 8.65E-07 4.86E-03 1.13E-06 1.04E-05 14 58 "NOL4,CDK5R1,CAPN3,RIMS4,SPATA2,SGIP1,RAPGEF6,KCNMA1,PLP1,STRN3,LRRTM4,CPEB4,TCEA1,PSD3" MicroRNA hsa-miR-34c-3p:Functional MTI Functional MTI miRTarbase 8.65E-07 4.86E-03 1.13E-06 1.04E-05 14 58 "ADARB2,AXIN2,OGT,PHF12,INSYN2B,FOXN3,PLCXD3,RABGAP1L,ANKFY1,FYN,NCKAP1,SCRG1,PPM1L,KIAA0930" MicroRNA hsa-miR-4720-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.83E-07 4.96E-03 1.15E-06 1.06E-05 16 75 "DMTF1,AFF2,CELF1,KLF12,TJAP1,IL6ST,MAP4,KLHL11,GLDN,COPZ1,RUFY2,TRIM67,SON,RAP1GAP2,ZMAT3,RASD2" MicroRNA hsa-miR-489-3p:Functional MTI Functional MTI miRTarbase 8.83E-07 4.96E-03 1.15E-06 1.06E-05 16 75 "KIAA0040,FEM1B,FRY,IQCG,ZBED3,NCKAP1,ADAM28,SPIN1,GNAL,PROX1,PXK,FNIP1,GSE1,RPL7L1,SF1,CADM2" MicroRNA hsa-miR-1915-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.90E-07 5.00E-03 1.16E-06 1.07E-05 31 232 "NDRG3,PTCHD1,MTA3,MARCH4,FOXK1,TMEM184B,RTTN,RNF14,FGFR1OP2,IP6K1,ELMSAN1,GNE,CNNM1,HEYL,EIF4G1,CELF1,NSG1,MSANTD4,GJB1,CRCP,KIAA1958,KIF3A,BACH2,NKD1,IL6R,FAM216A,ZNF844,RGS12,ACSL6,ERCC6L2,TSPAN11" MicroRNA hsa-miR-6074:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.94E-07 5.02E-03 1.17E-06 1.08E-05 17 84 "ADCYAP1R1,PTCH2,NUMB,EDN1,FCF1,YAF2,IL6ST,KCNK1,STMN1,PRKCB,BDP1,SS18,TBCEL,RBFOX2,ZNF28,CADM2,SLC38A1" MicroRNA hsa-miR-376b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 8.94E-07 5.02E-03 1.17E-06 1.08E-05 17 84 "MYRF,FOXK1,BTF3L4,RIMS2,YAF2,AMOTL2,FOXG1,GNAS,ATG4C,KCND3,CYP27C1,SHC3,ZNF426,ZNF844,ZNF667,SLC35G2,ZNF781" MicroRNA "TACGGGT,MIR-100:MSigDB" "TACGGGT,MIR-100:MSigDB" MSigDB 9.19E-07 5.16E-03 1.20E-06 1.11E-05 9 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,RAVER2,AP1AR,SLC44A1" MicroRNA "TACGGGT,MIR-99A:MSigDB" "TACGGGT,MIR-99A:MSigDB" MSigDB 9.19E-07 5.16E-03 1.20E-06 1.11E-05 9 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,RAVER2,AP1AR,SLC44A1" MicroRNA "TACGGGT,MIR-99B:MSigDB" "TACGGGT,MIR-99B:MSigDB" MSigDB 9.19E-07 5.16E-03 1.20E-06 1.11E-05 9 23 "MTMR3,HS3ST2,FGFR3,INSM1,MBNL1,EPDR1,RAVER2,AP1AR,SLC44A1" MicroRNA hsa-miR-6819-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.35E-07 5.25E-03 1.22E-06 1.12E-05 19 103 "CRLF1,ZNF385A,MICAL2,IP6K1,PLEKHM1,ELN,PDLIM5,GLI2,TNRC6A,PRRC2B,MDM4,MPP2,EPN1,SPATA6,MAPK10,KLHDC8A,FOXRED2,ATXN2,UBTF" MicroRNA hsa-miR-7161-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.35E-07 5.25E-03 1.22E-06 1.12E-05 19 103 "ZNF608,TRMT9B,SFMBT2,LDHD,CACNB2,BAG4,CNTNAP2,KATNAL1,PACSIN2,HMGB1,ZNF678,AFF1,MN1,PROX1,TCP11L1,YPEL4,EPB41L3,TSC1,CLDND1" MicroRNA hsa-miR-4315:mirSVR_highEffct hsa-miR-4315:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 9.46E-07 5.32E-03 1.23E-06 1.14E-05 24 154 "SUGT1P4-STRA6LP-CCDC180,ASPH,PTBP2,RUNX1T1,CCPG1,CLOCK,DDX46,EDN3,PRELID3A,MSTN,GPD2,SHISA6,TMEM240,SLC35G1,PRIMPOL,ITSN1,SH3GL3,RGL1,ADGRL3,AP4E1,TP53BP2,SSBP2,VPS35L,PLSCR4" MicroRNA hsa-miR-767-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.66E-07 5.43E-03 1.26E-06 1.16E-05 27 187 "CDC27,BTF3L4,GAPVD1,ELMSAN1,HP1BP3,SH3GLB1,FKTN,FUT9,DOT1L,KIAA1958,AGBL5,MYCN,NASP,ENPP2,STRN3,NWD1,KLHL11,FNIP1,SLITRK3,RUFY2,LRRC55,PEG10,MCF2L2,ZFP91,TRPS1,TUBB2A,LINC00632" MicroRNA hsa-miR-330-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.71E-07 5.46E-03 1.27E-06 1.17E-05 21 123 "SORCS2,ARHGDIA,ARRB2,BMP7,MYRF,CLU,SEZ6,IP6K3,MTHFD2,BVES,PDE3A,PDE4B,PDE1B,PKM,BCAS3,STX1B,STUM,MYH15,FBXL16,SSBP2,ZNF154" MicroRNA hsa-miR-542-3p:Functional MTI Functional MTI miRTarbase 9.78E-07 5.49E-03 1.27E-06 1.17E-05 26 176 "SLC12A5,KIAA1324,CDC14B,BMP7,FOXK1,CACNA1B,ZNF555,COL9A2,TBPL1,KIAA0408,GFRA1,IGFBP1,MDM4,NRGN,PIK3R1,STK32A,TMEM145,ATXN1,IL17RB,MCF2L2,MGRN1,SSBP2,USP1,SLC30A4,PRDM2,CSDE1" MicroRNA hsa-miR-486-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-06 5.63E-03 1.31E-06 1.20E-05 15 67 "MARCH4,ARHGAP5,NRP2,CLDN10,BTF3L4,G3BP2,DCTN4,CIT,ZIC5,PIK3R1,RCOR3,SP4,CADM1,CCDC14,ZDHHC20" MicroRNA hsa-miR-374c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-06 5.69E-03 1.32E-06 1.22E-05 11 36 "FAM135A,CREB5,HLF,HMGB1,MDM4,MYCN,SALL1,KLHL7,CAMSAP2,TUB,FMN2" MicroRNA hsa-miR-24-1-5p:Functional MTI Functional MTI miRTarbase 1.01E-06 5.69E-03 1.32E-06 1.22E-05 11 36 "SLITRK1,PNKD,ABI2,FOXM1,ELOVL5,NFIX,TMEM231,SP2,TPM4,DHX33,WNK1" MicroRNA hsa-miR-135a-5p:Functional MTI Functional MTI miRTarbase 1.02E-06 5.70E-03 1.32E-06 1.22E-05 18 94 "KIF6,APC,CDR1,HEYL,EGFR,AMOTL2,KIAA1958,JAK2,MBNL1,TNPO2,PTK2,PTPRD,PEX2,TTLL7,PPM1E,ARC,SLC19A3,VLDLR" MicroRNA hsa-miR-1469:mirSVR_lowEffct hsa-miR-1469:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 1.02E-06 5.72E-03 1.33E-06 1.22E-05 23 144 "ADARB2,SUGT1P4-STRA6LP-CCDC180,CALB2,MICAL2,LYPD1,DTNB,DNM1L,TSPAN5,POLK,GABRB1,FUT10,GRIA2,HAPLN2,SMAP1,TNPO2,NKAIN4,PRKCG,WDR25,MGRN1,TPCN2,TNS2,PIK3R5,TBC1D15" MicroRNA hsa-miR-1306-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.04E-06 5.86E-03 1.36E-06 1.25E-05 28 199 "RNF157,SORCS2,ATM,RNF14,MED12L,CPLX2,GJB1,CRCP,PCDH11X,SCRG1,METTL21A,KCND3,KCNN1,SAMD5,JAKMIP3,ALDH1L2,TMOD2,A2ML1,TNPO2,FITM2,RIMKLA,MAPKBP1,SMOC1,INKA2,KLHL7,ALG1,ZBTB16,RNF170" MicroRNA hsa-miR-4297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-06 5.98E-03 1.38E-06 1.28E-05 17 85 "THSD7A,NRG2,PITPNM3,SCRN1,IP6K1,SRARP,TXNL4A,PTPRT,LSAMP,CHST6,POU3F2,NWD1,KIAA0895L,STUM,MGRN1,TPM3,JMJD1C" MicroRNA hsa-miR-6753-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-06 5.98E-03 1.38E-06 1.28E-05 17 85 "PHF12,ATP1A1,FMNL3,IPCEF1,SCML2,DLC1,BRSK1,PRRC2B,DDX19B,HMGB1,KCNH1,TTYH2,MDFI,NUMA1,PALM,ALG9,MPPE1" MicroRNA hsa-miR-379-5p:Functional MTI Functional MTI miRTarbase 1.06E-06 5.98E-03 1.38E-06 1.28E-05 17 85 "ALDH4A1,SLC2A11,MICAL2,DNAL1,EDN1,TUBD1,EPS8,POLL,TDRKH,DDX19B,MDM4,BEST3,MTRF1L,GDPD1,PTK2,ZYG11B,TPD52" MicroRNA hsa-miR-6842-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-06 5.98E-03 1.38E-06 1.28E-05 17 85 "ADAR,ARHGDIA,CACNA1A,NEURL1,C1orf52,NIPBL,SV2B,MRVI1,CELF1,ADAP1,IBA57,MMP17,PEX2,RAB5B,MAGI3,MAPK8IP3,ZNF24" MicroRNA hsa-miR-3977:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-06 5.99E-03 1.39E-06 1.28E-05 16 76 "ZNF578,ARSE,PRC1,MTMR7,CNRIP1,BLOC1S6,WDPCP,LILRA2,ZBTB49,KPNA5,LSAMP,RFX3,ERBIN,ZNF610,UBE2H,URM1" MicroRNA hsa-miR-7849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-06 5.99E-03 1.39E-06 1.28E-05 16 76 "TMTC1,ASB3,FDFT1,ZNF589,SEMA4D,JKAMP,PNMA2,DIPK1C,ZNF546,NEUROD1,PDE3A,PKIA,ACSS3,SON,TSN,WNK1" MicroRNA hsa-miR-3074-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-06 6.07E-03 1.41E-06 1.29E-05 14 59 "RALGAPA1,VXN,MYADM,NPTN,MSANTD4,KCNMB4,LYPLAL1,MDM4,AFF1,PAK3,HSPA4L,NECAB1,ANKRD28,MTCH1" MicroRNA hsa-miR-199a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.09E-06 6.12E-03 1.42E-06 1.30E-05 25 166 "MAP4K3,DDR1,CDH2,CLTC,EDN1,ERBB2,RND1,DDX19B,ARHGAP12,XRRA1,PDE4D,TMOD2,PIK3CD,A2ML1,POLR2F,ZNF844,SLC8A1,ZFP1,SNAP25,ZNF415,SIRT1,DDHD1,PLPP4,ZNF195,WNK1" MicroRNA hsa-miR-365a-3p:Functional MTI Functional MTI miRTarbase 1.11E-06 6.26E-03 1.45E-06 1.33E-05 21 124 "ADCYAP1R1,PCDH10,SLC7A14,BTF3L4,AKAP12,CS,ABI2,POLR1B,COMMD5,PAX6,PPP2R5E,KANSL1,SNRK,CYB561D1,PCMTD2,MCMBP,SGK1,ANKRD12,USP22,ZXDA,TRIM16L" MicroRNA hsa-miR-7974:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-06 6.89E-03 1.59E-06 1.47E-05 15 68 "SYNJ2,CACNA1A,C1orf52,NDST3,AKAP6,KIAA0040,PHF19,B4GALNT4,ADAP1,KCNIP3,PEX26,UNC80,FNBP1,PEG10,THRA" MicroRNA hsa-miR-5581-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-06 7.10E-03 1.64E-06 1.51E-05 17 86 "THSD7A,NRG2,PITPNM3,SCRN1,IP6K1,SRARP,TXNL4A,PTPRT,LSAMP,CHST6,POU3F2,NWD1,KIAA0895L,STUM,MGRN1,TPM3,JMJD1C" MicroRNA hsa-miR-770-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-06 7.10E-03 1.64E-06 1.51E-05 17 86 "ARHGAP5,CS,RIMS3,GOLGA7,ERCC2,MDM4,ADAM22,ZNF426,FBXW7,MEG3,BTBD3,ZNF667,RCOR3,ATP11A,DDHD1,ZNF23,ZNF138" MicroRNA hsa-miR-4301:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-06 7.10E-03 1.64E-06 1.51E-05 17 86 "OSBPL1A,PHF12,BACH1,CAMK2G,FGFR1OP2,CELSR3,SEMA4D,POLL,NFYA,CNNM2,PTAFR,SH3TC2,SPIN3,KANSL3,TBX15,DPYSL5,GAN" MicroRNA hsa-miR-139-5p:Functional MTI Functional MTI miRTarbase 1.27E-06 7.12E-03 1.65E-06 1.52E-05 19 105 "PDE4DIP,USP6NL,ARHGAP32,STAMBP,TNRC6A,HSP90AA1,KCND3,KSR2,PDE4D,NCR3LG1,CHD9,SMARCA4,ADAMTS17,SYT5,TCF12,TPD52,CFAP298,CIAPIN1,SPATA13" MicroRNA hsa-miR-3186-5p:mirSVR_highEffct hsa-miR-3186-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.27E-06 7.12E-03 1.65E-06 1.52E-05 19 105 "TKTL1,CAPRIN2,VSTM2A,SOCS5,EDIL3,APH1A,UBE2E3,GABRB1,ARPP21,BTN2A1,MYLK2,NME4,KIAA0895L,ARX,SLC15A2,NAXD,CEP68,EML6,PCDH15" MicroRNA "TAGGTCA,MIR-192:MSigDB" "TAGGTCA,MIR-192:MSigDB" MSigDB 1.28E-06 7.18E-03 1.66E-06 1.53E-05 12 44 "PCDH19,ALCAM,PKP4,LRRFIP1,NIPBL,DBT,DYRK1A,LPAR4,LARP4,ADGRL3,TCF7,RICTOR" MicroRNA "TAGGTCA,MIR-215:MSigDB" "TAGGTCA,MIR-215:MSigDB" MSigDB 1.28E-06 7.18E-03 1.66E-06 1.53E-05 12 44 "PCDH19,ALCAM,PKP4,LRRFIP1,NIPBL,DBT,DYRK1A,LPAR4,LARP4,ADGRL3,TCF7,RICTOR" MicroRNA hsa-miR-522-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.29E-06 7.26E-03 1.68E-06 1.54E-05 20 115 "APP,LDHD,EVI5L,CPS1,DYRK1A,FEM1B,DCTN4,SRARP,RTN3,SCML2,PCSK2,CCSER2,TNPO2,FAT3,FIGN,SOX2,LHPP,TPD52,DHX33,NETO2" MicroRNA hsa-miR-3192-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-06 7.55E-03 1.74E-06 1.60E-05 14 60 "ADD2,CFL2,FOXN3,OSBPL3,RUSC2,SH3GLB1,MALT1,RAB30,POLL,L1CAM,ARHGAP12,REEP1,WNK3,FXR1" MicroRNA hsa-miR-3164:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-06 7.55E-03 1.74E-06 1.60E-05 14 60 "FMNL2,ELFN2,USP37,CA12,APPL1,TRMO,TJAP1,IL6ST,FAT3,POLR2F,PEX26,ZFP1,LIMCH1,ZXDA" MicroRNA hsa-miR-892a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-06 7.55E-03 1.74E-06 1.60E-05 14 60 "SDE2,KATNAL1,ZIC4,DIPK1C,AP4S1,RBPJ,IL6ST,KLHL23,LIMS1,MBNL1,MMP16,ALG9,ELP2,TPM1" MicroRNA hsa-miR-658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-06 7.67E-03 1.77E-06 1.63E-05 25 168 "SLC24A4,FOXK1,CDR1,JAM2,NCOR2,ELAVL3,ZNF549,FECH,KBTBD12,NCKAP1,PRRC2B,MDM4,PIK3CD,FXYD1,RBBP8,PTGR2,FNIP1,LIMS2,FNBP1,MCF2L2,FBXL16,NACC2,TPM3,RFTN2,TBC1D15" MicroRNA hsa-miR-4684-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-06 7.74E-03 1.78E-06 1.64E-05 13 52 "TRMT9B,SLC7A14,FOXN3,ZFYVE9,G3BP2,YAF2,RTN3,KAT7,PDE3A,RAVER2,TPM4,TUBB2A,SLC30A4" MicroRNA "AGTCTAG,MIR-151:MSigDB" "AGTCTAG,MIR-151:MSigDB" MSigDB 1.40E-06 7.89E-03 1.82E-06 1.67E-05 9 24 "RTL9,CACNB4,LSMEM2,NTM,HPCAL4,KLF12,BRINP3,NELL1,CAMTA1" MicroRNA hsa-miR-3178:mirSVR_highEffct hsa-miR-3178:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.40E-06 7.89E-03 1.82E-06 1.67E-05 9 24 "SORBS3,NRN1,TUBB3,STAU2,HSD17B1,CELF5,CDK18,KCNE5,SF1" MicroRNA hsa-miR-639:PITA hsa-miR-639:PITA_TOP PITA 1.40E-06 7.89E-03 1.82E-06 1.67E-05 9 24 "LYPD1,GPR61,AGAP2,TBR1,KCND1,LSS,MSI1,NRGN,KANSL1" MicroRNA hsa-miR-19b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-06 8.27E-03 1.90E-06 1.75E-05 19 106 "ARID1A,CACNB2,CD38,DMD,EDN1,CBX1,RASSF8,MDM4,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,ZNF384,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-6507-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-06 8.27E-03 1.90E-06 1.75E-05 19 106 "SEMA6A,SEMA7A,CDC25B,DCAF8,FAM107B,FEM1B,EFNA2,RAB41,IL6ST,NEK1,RASGEF1B,PROX1,MCMBP,NAXD,SPART,SMOC1,FAM208A,CLASP1,SMUG1" MicroRNA hsa-miR-6865-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.47E-06 8.27E-03 1.90E-06 1.75E-05 19 106 "MARCH4,LRFN1,C6orf89,API5,CACNB2,ZNF445,STOML1,AMOTL2,SMC2,STAG2,ELOVL5,KCNN3,KIFC3,PFKFB3,STX1B,UHRF1BP1L,TMEM151B,ZMAT3,SLC44A1" MicroRNA hsa-let-7b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.36E-03 1.92E-06 1.77E-05 20 116 "SPAG9,C1orf52,MYOM2,COPB2,MYADM,SEMA4D,GABRG1,BRPF3,LRRC75A,ZNF181,ZNF546,NCOA7,MBNL1,OCIAD1,CNKSR2,RUFY2,DIP2A,SYT4,GPRIN3,WNK1" MicroRNA hsa-miR-1178-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.39E-03 1.93E-06 1.78E-05 15 69 "ABCF1,SFMBT2,CCPG1,PLXNA4,ABI2,GPR155,PPP3CB,MAPK9,RDX,UEVLD,HUNK,ANKRD36,ZMAT3,RPL7L1,PLSCR4" MicroRNA hsa-miR-1273h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.39E-03 1.93E-06 1.78E-05 15 69 "ARHGDIA,CLTA,COL9A1,CPS1,PHF19,ABCC5,SLC43A2,GABRB3,RNF165,CYP27C1,AFF1,SLC25A36,VSNL1,PMEPA1,GAN" MicroRNA hsa-miR-3128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-06 8.39E-03 1.93E-06 1.78E-05 15 69 "MTMR3,CCNT1,CDC27,GOLGA7,ZNF234,PRRC2B,PADI2,PDE3A,DPF2,SEC31A,KANSL3,SLC6A8,KIAA0930,DPYSL5,FAM182B" MicroRNA hsa-miR-6781-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.50E-06 8.41E-03 1.93E-06 1.78E-05 17 87 "TXNDC16,DIRAS1,APPL1,NKX6-2,SEPT9,GRK4,TPPP,NEUROD2,NFIX,POU3F2,NCBP3,ZKSCAN3,SP2,MPRIP,STX1A,BHLHB9,TMEM63C" MicroRNA hsa-miR-3145-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-06 8.64E-03 1.98E-06 1.83E-05 16 78 "CBS,COL9A2,C2CD2L,FSD1L,CRCP,RAPGEF1,BACH2,KCNB1,NFIA,NPTX1,PAX6,TMOD2,CCSER2,FNBP1,TNR,AGMO" MicroRNA hsa-miR-6511a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-06 8.64E-03 1.98E-06 1.83E-05 16 78 "RUNX1T1,JAKMIP2,RCAN2,CELF1,MPP6,GABRA4,GGT7,ADAMTS13,HNRNPK,ZDHHC22,C12orf49,SNX22,HUNK,AJAP1,ZNF781,ZNF195" MicroRNA hsa-miR-7156-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-06 8.88E-03 2.04E-06 1.88E-05 22 137 "SEMA6A,PHF12,DST,CSNK1G3,ZBTB24,C8orf37,TMEM132C,CAB39,IL6R,IBA57,ZNF680,MYBPC1,OPHN1,GPR137C,ACER3,DRAXIN,CPEB3,BDP1,MPRIP,RFTN2,UBE2H,WIPF2" MicroRNA hsa-miR-563:PITA hsa-miR-563:PITA_TOP PITA 1.66E-06 9.34E-03 2.14E-06 1.97E-05 12 45 "PTCHD1,KLHL13,MICAL2,FGF13,TCERG1,PBRM1,RTN1,VWC2,TRIM2,UBE3A,MFF,WNK3" MicroRNA hsa-miR-27a-5p:Functional MTI Functional MTI miRTarbase 1.66E-06 9.34E-03 2.14E-06 1.97E-05 12 45 "ADD1,DIRAS1,EGFR,UFM1,ZMAT1,POLL,MXI1,NPTX1,PPARA,SPIN3,SNAP25,TUBB2A" MicroRNA hsa-miR-6787-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-06 9.34E-03 2.15E-06 1.98E-05 21 127 "DPF1,PTCHD1,PDZD4,PRX,ARHGDIA,EVI5L,ZNF385A,MICAL2,MYADM,MTSS1L,NEUROD2,NRGN,PACSIN1,C12orf49,PTGR2,SBF1,SLC1A2,PEX26,WBP2,VGF,ZNF154" MicroRNA hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-06 9.35E-03 2.15E-06 1.98E-05 14 61 "TAOK1,C6orf89,FOXK1,SIRPA,SCARA3,RNF165,MAPT,MYBPC1,PEX2,PRRT2,CLIP1,SARS,NACC2,SF1" MicroRNA hsa-miR-6820-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-06 9.35E-03 2.15E-06 1.98E-05 14 61 "FMNL2,ELFN2,USP37,CA12,APPL1,TRMO,TJAP1,IL6ST,FAT3,POLR2F,PEX26,ZFP1,LIMCH1,ZXDA" MicroRNA hsa-miR-5688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.70E-06 9.57E-03 2.20E-06 2.02E-05 25 170 "TMEFF1,MTMR9,KIAA1549L,BTF3L4,MYADM,DGKB,DLC1,HSP90AA1,C5orf24,IL6R,MSANTD3-TMEFF1,NCAM2,OCRL,PCMT1,TNPO2,CRLS1,PRRT2,ZNF354C,TRIM67,TAB2,LRRC4,MPRIP,ARL10,SF1,ADAMTS9" MicroRNA hsa-miR-1272:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-06 9.94E-03 2.28E-06 2.10E-05 17 88 "ATP1B3,TOGARAM2,PPP1R16B,CACNG7,TUBA1B,MMADHC,KIAA1958,MDM4,MYBPC1,OPHN1,GPR137C,KANSL1,CNNM2,CSRNP3,ALG1,TCEA1,RTN4" MicroRNA hsa-miR-1283:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.77E-06 9.94E-03 2.28E-06 2.10E-05 17 88 "CANX,CDC27,ENPP6,FREM1,TCERG1,RNPS1,FICD,MARK1,GPR137C,PCMT1,BEST3,PKIA,PTPRB,CLASP1,SLC44A1,FRRS1L,SPATA13" MicroRNA hsa-miR-8052:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-06 1.01E-02 2.31E-06 2.12E-05 22 138 "ESYT2,ATP1B3,ZMYM4,CBARP,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,WASF3,TDRKH,KCNK3,NUCB1,PCSK2,TNPO2,IGSF9B,SON,ARHGAP26,TPM3,LAT2,CFAP298" MicroRNA hsa-miR-3199:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.79E-06 1.01E-02 2.31E-06 2.12E-05 22 138 "ESYT2,ATP1B3,ZMYM4,CBARP,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,WASF3,TDRKH,KCNK3,NUCB1,PCSK2,TNPO2,IGSF9B,SON,ARHGAP26,TPM3,LAT2,CFAP298" MicroRNA hsa-miR-518e:PITA hsa-miR-518e:PITA_TOP PITA 1.80E-06 1.01E-02 2.32E-06 2.14E-05 10 31 "ZNF608,NRXN1,ZNF521,ZNF385A,SLC32A1,SOCS5,EGR3,SCRT2,NEXMIF,MCF2L" MicroRNA hsa-miR-3619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.80E-06 1.01E-02 2.32E-06 2.14E-05 10 31 "ADD1,OGT,BSN,GUCY1A2,C2orf72,IL6R,SHC3,PDE2A,MTMR10,WIPF2" MicroRNA hsa-miR-654-3p:Functional MTI Functional MTI miRTarbase 1.81E-06 1.02E-02 2.33E-06 2.15E-05 15 70 "ZNF578,PTBP2,KIAA1549L,BTF3L4,SDC3,EXOG,FOXG1,GABRG1,KCNK10,PDPK1,PKIA,BSDC1,ZMAT3,ZNF610,PMEPA1" MicroRNA hsa-miR-4504:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-06 1.02E-02 2.33E-06 2.15E-05 15 70 "FOXK1,CACNA1B,TBPL1,SOCS5,KIAA0408,RABGAP1L,FOXG1,GFRA1,KIT,FOXRED2,ATXN1,TPCN2,ZNF708,PRDM2,CSDE1" MicroRNA hsa-miR-31-3p:Functional MTI Functional MTI miRTarbase 1.81E-06 1.02E-02 2.33E-06 2.15E-05 15 70 "BACH1,FBXL5,GABRB1,NUCB1,PAX6,PDE4D,EPB41L4B,PPP2R5C,PLEKHB2,NLGN1,PUM2,DICER1,RPL7L1,RICTOR,SLC38A1" MicroRNA hsa-miR-6752-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-06 1.05E-02 2.40E-06 2.21E-05 23 149 "ANK1,ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIK2,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,TPM3,RICTOR,ZDHHC20" MicroRNA hsa-miR-7110-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-06 1.05E-02 2.40E-06 2.21E-05 23 149 "ANK1,ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIK2,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,TPM3,RICTOR,ZDHHC20" MicroRNA hsa-miR-6842-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-06 1.05E-02 2.40E-06 2.21E-05 23 149 "ANK1,ARHGDIA,PYGO1,DBT,SGSM2,MTSS1L,DOT1L,GRIK2,GRIN2D,KCNK3,MYO5A,ZC3H12B,PKM,NLE1,PLEC,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,TPM3,RICTOR,ZDHHC20" MicroRNA hsa-miR-550b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-06 1.07E-02 2.44E-06 2.24E-05 21 128 "CLK4,XKR4,PTBP2,CBS,DNAL1,DYRK1A,ATP13A4,SCRG1,KNDC1,IBA57,KCNJ11,CHST6,MDM4,RAD51D,RBBP8,ATF7IP,SOX11,TMEM151B,PPIL6,SSBP2,ZNF70" MicroRNA hsa-miR-1276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-06 1.07E-02 2.45E-06 2.25E-05 24 160 "INTS2,APP,CALM1,SLC16A4,AKAP6,PLEKHM1,CHRDL1,DPP6,STARD3NL,TUBD1,WAC,TRMO,SARAF,PTPRT,LAMP2,MAT2A,GPR137C,PDZRN4,SON,TAB2,TBL1X,TPM3,WIPF2,VANGL2" MicroRNA hsa-miR-4432:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-06 1.07E-02 2.46E-06 2.26E-05 18 98 "TMEM170A,KATNAL1,TRMO,CELF1,CRCP,GPR75,SOWAHA,KNDC1,ZNF678,KPNA5,ARHGAP12,CHST6,PROX1,ZNF844,TMEM178B,TMEM9,PITPNB,TBC1D15" MicroRNA "CGCTGCT,MIR-503:MSigDB" "CGCTGCT,MIR-503:MSigDB" MSigDB 1.95E-06 1.09E-02 2.50E-06 2.30E-05 8 19 "ACHE,PPFIA3,BSN,USP2,IP6K1,EIF4G1,ING4,ZNF423" MicroRNA hsa-miR-127-3p:TargetScan hsa-miR-127-3p TargetScan 1.95E-06 1.09E-02 2.50E-06 2.30E-05 8 19 "ATP2B2,FMNL3,RIMS4,MTSS1L,MAPK4,BCAS3,CYB561D1,LAS1L" MicroRNA hsa-miR-6761-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.97E-06 1.11E-02 2.53E-06 2.33E-05 19 108 "KLHL32,ARHGDIA,TMEM184B,SLC43A2,MRVI1,SRRM4,HTR2A,SLC35G1,NUCB1,GPR173,PRKAB2,ATP8B4,CSRNP3,COPZ1,TMCC1,ASTN2,PRMT8,ZNF45,ZNF74" MicroRNA hsa-miR-4502:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-06 1.15E-02 2.63E-06 2.42E-05 14 62 "FZD9,INTS2,MTMR9,ANKRD44,RUSC2,CHST15,SYNCRIP,SMC2,KPNA5,MMP16,PDE4D,TMEM200C,MBD5,ZNF708" MicroRNA hsa-miR-2467-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-06 1.17E-02 2.67E-06 2.46E-05 17 89 "SLC24A4,TAOK1,CEP126,ARHGDIA,CCNT1,CRY2,RIMS4,KIAA0408,TPPP,SETD5,C12orf49,CLSTN1,WDTC1,DDN,ARC,WNK1,URM1" MicroRNA hsa-miR-1204:PITA hsa-miR-1204:PITA_TOP PITA 2.10E-06 1.18E-02 2.69E-06 2.48E-05 9 25 "ASIC1,ADGRB1,CFL2,KMT2C,RND1,GRIN2D,MAP2,PDPK1,GTDC1" MicroRNA hsa-miR-1200:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-06 1.20E-02 2.73E-06 2.52E-05 24 161 "ELFN2,RNF157,TNRC6C,ASTN1,CDC25B,DNAJB5,CPS1,FGFR1OP2,NCKAP1,SIGLEC8,HMGB1,ZDHHC15,METTL21A,CHIC1,C10orf105,NODAL,P2RX7,PEX26,MAPK8IP3,ZMAT3,ZNF106,RPL7L1,UGT8,LMAN2L" MicroRNA hsa-miR-342-5p:PITA hsa-miR-342-5p:PITA_TOP PITA 2.15E-06 1.21E-02 2.75E-06 2.53E-05 12 46 "PDZD4,CNIH2,CCAR2,SNAP91,DLG4,ZIC4,PPARGC1A,GRIN1,NFIX,TMEM255A,CPEB3,FAM214B" MicroRNA hsa-miR-5004-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.23E-02 2.80E-06 2.58E-05 13 54 "GREB1,PUM1,SRRM4,HLF,MAOB,C1orf109,NKAIN1,GSTCD,TMEM100,PGBD4,UHRF1BP1L,TBX15,PARD3" MicroRNA hsa-miR-3677-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.23E-02 2.80E-06 2.58E-05 13 54 "TAOK1,FOXK1,IP6K1,CELF1,GATM,HMGB1,MAPT,SMOX,PTPA,KANK1,ZC3H4,DDHD2,FBXO36" MicroRNA hsa-miR-556-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.23E-02 2.80E-06 2.58E-05 13 54 "ALAD,TRMT9B,SRSF11,UBXN2A,USP6NL,G3BP2,SALL3,COPS8,ZIC5,MYCN,SETD5,NR2C2,CLDND1" MicroRNA hsa-miR-3141:mirSVR_highEffct hsa-miR-3141:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.19E-06 1.23E-02 2.80E-06 2.58E-05 16 80 "MTMR7,VAC14-AS1,SGK2,EPHB1,MED12L,CCDC184,GRM2,IL6ST,MBD1,LDLRAD3,PCSK5,MEG3,SLC6A9,ANKRD36,SPTAN1,CBLN2" MicroRNA hsa-miR-4433a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.19E-06 1.23E-02 2.81E-06 2.58E-05 15 71 "SLC12A5,MTUS1,MYADM,TOMM20,SORBS3,TNK2,SYNPO,SLC6A17,PSAT1,NDUFS7,MAP6D1,SHANK2,WBP2,VLDLR,ZNF24" MicroRNA hsa-miR-29b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.25E-06 1.26E-02 2.88E-06 2.65E-05 20 119 "SDE2,SORCS2,MARCH4,CDK13,DYNLL1,STX16,CREB5,PLEKHM1,DLC1,TCERG1,LSAMP,GPR155,KITLG,SH3BP2,ZNF415,GANAB,NACC2,TPM3,ZNF195,ZNF248" MicroRNA hsa-miR-19a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-06 1.28E-02 2.91E-06 2.68E-05 19 109 "ARID1A,CACNB2,CD38,DMD,EDN1,CBX1,RASSF8,MDM4,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,ZNF384,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-4425:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.45E-06 1.38E-02 3.13E-06 2.89E-05 17 90 "XKR4,LDHD,CTNND1,DNAL1,DNAJC6,ST8SIA3,GPR61,TJAP1,PDE3A,MINDY2,FBXW7,FAM126B,STAU1,SULF2,NSD1,DPYSL5,GAN" MicroRNA hsa-miR-604:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.46E-06 1.38E-02 3.14E-06 2.89E-05 11 39 "GPRIN1,SLC25A25,NCOA1,NIPBL,SV2B,MRVI1,SRRM4,MSI1,NFIX,SLC1A7,ZNF610" MicroRNA hsa-miR-424-3p:Functional MTI Functional MTI miRTarbase 2.51E-06 1.41E-02 3.20E-06 2.95E-05 10 32 "APP,WAC,GABRB3,MAT2A,PDE4D,RGR,ALG1,ZFP91,TRIM16L,NETO2" MicroRNA hsa-miR-4474-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-06 1.41E-02 3.21E-06 2.96E-05 14 63 "BRAP,CFAP410,CRY2,SOCS5,LIN54,DMTF1,PRRC2B,RBPJ,SCRT2,ZNF678,ALDH1L2,NOVA2,MRPS18A,ZNF331" MicroRNA hsa-miR-4486:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.58E-06 1.45E-02 3.30E-06 3.04E-05 22 141 "SLC16A4,CLU,RIPOR2,HP1BP3,ANKFY1,TRMO,UFM1,FUT9,MSANTD4,IRAK3,KCNN3,CHST6,MYBPC1,PKM,PPP1R1A,BCAS3,ELP2,STUM,ARL10,PPIL6,UBC,ZNF154" MicroRNA hsa-miR-6834-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.59E-06 1.45E-02 3.31E-06 3.05E-05 18 100 "ELFN2,OGT,ASTN1,ARHGEF2,ZNF385A,ABCC5,GSN,MMP17,NDUFA5,NCR3LG1,MORC4,SLC2A5,SMOC1,SEPT8,CBX5,TPD52,TPM2,TUBB2A" MicroRNA hsa-miR-382-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.60E-06 1.46E-02 3.32E-06 3.06E-05 16 81 "XKR4,CALM1,HP1BP3,C8orf37,ENO2,APOPT1,TNRC6A,PRUNE2,MAP2,MYO6,PRRX1,CPEB4,CDK19,TGFBR3,MEAF6,SPATA13" MicroRNA hsa-miR-1226-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.60E-06 1.46E-02 3.32E-06 3.06E-05 16 81 "ELFN2,OGT,ASTN1,ARHGEF2,CBARP,PHYHIP,ABCC5,CHST15,GSN,ARHGAP12,MMP17,SLC2A5,SMOC1,SEPT8,CBX5,TPD52" MicroRNA hsa-miR-3909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.60E-06 1.46E-02 3.32E-06 3.06E-05 16 81 "SERPINA3,ATP2B3,UBXN2A,PLEKHM1,GCK,NR3C1,PTPRT,ZNF678,KCNJ10,PKM,C11orf49,ZMAT3,TNFRSF1B,ZNF154,PMEPA1,MVB12B" MicroRNA hsa-miR-34a-3p:Functional MTI Functional MTI miRTarbase 2.60E-06 1.46E-02 3.32E-06 3.06E-05 16 81 "SDE2,AXIN2,AK2,NCOR1,NCOR2,PPP1R16B,SH3GLB1,MTHFD2,LYVE1,MMP17,PDE4B,CPEB4,SIRT1,RPL7L1,ZNF711,URM1" MicroRNA hsa-miR-3126-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-06 1.47E-02 3.34E-06 3.08E-05 19 110 "ELFN2,ZNF385A,ENTPD4,TRAPPC9,EIF4G1,MTSS1L,HBS1L,GSN,NDUFA5,TNPO2,NCR3LG1,MORC4,MYO18A,CAMTA2,SMOC1,NACC2,TPM2,TUBB2A,PMEPA1" MicroRNA hsa-miR-8089:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-06 1.47E-02 3.34E-06 3.08E-05 19 110 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,GPR26,TLX1,KCNN3,WBP1L,C12orf49,CLSTN1,LHFPL4,UNC5B,SSTR1,LAT2" MicroRNA hsa-miR-3692-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-06 1.48E-02 3.36E-06 3.10E-05 15 72 "BAG4,MICAL2,DCAF8,SV2B,ELAVL3,FER,ZBED3,PNMA2,GRIK3,FICD,ADAM22,MYCN,NEUROD1,C12orf49,NCBP3" MicroRNA hsa-miR-4727-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.64E-06 1.48E-02 3.36E-06 3.10E-05 15 72 "SLC7A14,REPS2,TOGARAM2,CPS1,BOC,YTHDC1,EDN1,EDN3,EPB41,CELF1,GPR45,ZNF546,MDGA1,PLCL1,AGMO" MicroRNA hsa-miR-1225-3p:PITA hsa-miR-1225-3p:PITA_TOP PITA 2.64E-06 1.48E-02 3.36E-06 3.10E-05 15 72 "PITPNM2,SH2B1,DUSP9,ELAVL3,GABRB3,CPLX2,TNRC6A,NEFM,CAMKV,RNF220,RORB,MYO18A,MYT1L,TEX2,AMACR" MicroRNA hsa-miR-184:Functional MTI Functional MTI miRTarbase 2.73E-06 1.53E-02 3.48E-06 3.21E-05 13 55 "GPRIN1,ARHGDIA,TPP1,CSF1,TM9SF4,LIFR,PKM,TNPO2,PTPA,PRKCB,ZFPM2,LRRC8A,KLC2" MicroRNA hsa-miR-582-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.73E-06 1.53E-02 3.48E-06 3.21E-05 13 55 "AXIN2,NFS1,ENTPD4,FER,DKK3,GRM5,KCNC1,MPP2,WBP1L,LRRK2,SCN4B,ARL10,GAN" MicroRNA hsa-miR-642b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.75E-06 1.54E-02 3.50E-06 3.23E-05 12 47 "XKR4,SORCS2,CACNA1A,ZNF385A,NEURL4,SLC35G1,NPTX1,PSAT1,DPF2,WDR37,ALG1,ZDHHC20" MicroRNA hsa-miR-146b-5p:Functional MTI Functional MTI miRTarbase 2.93E-06 1.65E-02 3.73E-06 3.44E-05 20 121 "PLEKHG5,NSL1,MICAL2,EGFR,ERBB4,MRPL10,GPM6B,KIT,MMP16,MPP2,MYO6,NOVA1,PDGFRA,KCTD15,ELP2,RUFY2,NSFL1C,TMEM136,TLR4,TMPRSS5" MicroRNA hsa-miR-4452:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-06 1.65E-02 3.73E-06 3.44E-05 20 121 "OSBPL8,ZNF578,PROM1,GABRB1,RAPGEF1,IBA57,LAMA2,PDPK1,PPP2R5E,SH3TC2,ZFP1,ZNF415,BDP1,PEG10,TMEM136,HEY2,KCNT2,ZNF195,TFIP11,XKR7" MicroRNA hsa-miR-1205:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-06 1.69E-02 3.82E-06 3.52E-05 18 101 "STX16,DCC,DLC1,ATOH8,KCNH2,MSI1,ENPP2,PKM,MTRF1L,RAB5B,HES6,RUFY2,SMARCE1,CLASP1,KCTD2,UBE2H,SF1,GDPD5" MicroRNA hsa-miR-4792:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-06 1.69E-02 3.82E-06 3.52E-05 18 101 "SYN3,PPP1R16B,DNAH9,FGFR1,ANKFY1,GPR75,POLL,SHISAL1,NOS1,PLEC,C12orf49,SCN4B,EPN2,EMC1,ACSBG1,NACC2,ZNF70,GAN" MicroRNA hsa-let-7e*:mirSVR_highEffct hsa-let-7e*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.00E-06 1.69E-02 3.82E-06 3.52E-05 18 101 "ADD1,MAGEE2,ZNF521,ARHGAP24,MAGI2,HS3ST2,AASDH,PLEKHA1,SYNCRIP,HNMT,CREG2,NF1,FERMT1,SPHKAP,MAST1,FRYL,TMEM163,GAN" MicroRNA hsa-miR-6823-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.01E-06 1.69E-02 3.83E-06 3.53E-05 19 111 "ARID1A,ARSE,ATP1A2,DLC1,MYOZ2,TNRC6A,GRK4,ZHX1,PPM1L,MINDY2,ZYG11B,UEVLD,FBXW7,RMI1,GALNT10,MAPKBP1,PCDHA6,ZNF74,ITM2C" MicroRNA hsa-miR-605-5p:Functional MTI Functional MTI miRTarbase 3.01E-06 1.69E-02 3.83E-06 3.53E-05 19 111 "SPOP,ABCD2,CACNA1A,CACNA1E,BTF3L4,IP6K1,RCAN1,AASDH,EDN3,CAP2,KIAA1958,GPM6B,ZNF678,SFXN5,SULF2,NR2C2,PRDM2,RTN4,GAN" MicroRNA hsa-miR-4708-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-06 1.72E-02 3.90E-06 3.59E-05 14 64 "ARID1A,INTS2,PUM1,MATR3,DNM2,SCML2,TACC2,RBPJ,PSD,SCN2B,CAMTA2,SATB2,CLASP1,NSD1" MicroRNA hsa-miR-3156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-06 1.72E-02 3.90E-06 3.59E-05 14 64 "PROM1,CANX,CD86,RABGAP1L,RBM12,LILRA2,ATXN2L,ZIC5,PCSK1,SLC37A2,ITGB3BP,SLC44A1,ARL10,VANGL2" MicroRNA hsa-miR-4804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-06 1.72E-02 3.90E-06 3.59E-05 14 64 "AFF2,CELF1,KLF12,IL6ST,KLHL11,RPRD1A,GSTCD,GLDN,COPZ1,TRIM67,SON,RAP1GAP2,ZMAT3,RASD2" MicroRNA hsa-miR-4705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-06 1.72E-02 3.90E-06 3.59E-05 14 64 "BMPR1B,ZNF555,ZMYM4,DBT,VPS13B,MTSS1L,SRARP,MIER3,USP51,IBA57,NLGN1,KANSL3,DICER1,AMACR" MicroRNA hsa-miR-569:Functional MTI Functional MTI miRTarbase 3.07E-06 1.72E-02 3.90E-06 3.59E-05 14 64 "EIF5,NCALD,TUBA1B,HLF,SESN3,MYBPC1,NAP1L1,DDR2,GPSM2,FITM2,UBR7,SLC25A36,NAXD,ZNF711" MicroRNA hsa-miR-181a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-06 1.73E-02 3.91E-06 3.60E-05 16 82 "ARID1A,PNMA8B,GRAMD1B,TAOK1,ATP1A3,ABCG2,NOS1AP,NSG2,MIER3,THYN1,PPP3CB,PSD,SEC61A2,ATXN2,ZNF138,WNK1" MicroRNA hsa-miR-936:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-06 1.73E-02 3.91E-06 3.60E-05 16 82 "COL4A5,RIMS3,BLOC1S6,RGS17,ZNF391,ZNF585B,MBNL1,CCDC80,MTRF1L,TMEM104,CLIP1,TAB2,ZFP91,ZNF384,RGMB,WNK2" MicroRNA hsa-miR-4470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.08E-06 1.73E-02 3.91E-06 3.60E-05 16 82 "DPY19L3,CDC27,BTF3L4,CTH,PLEKHA1,FUT10,MDM4,CTNNA3,MYBPC1,NPTX1,RAP1GDS1,REV3L,LRRC55,RGMB,TRPC3,EVI5" MicroRNA hsa-miR-1254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.15E-06 1.77E-02 4.00E-06 3.68E-05 21 132 "CLK4,HECW2,KIF6,APBB2,CDC14B,CLU,KLHL3,PHC2,ERBB2,ANKMY1,PCYOX1,GPR153,NXPH3,C2orf72,OLR1,PKM,RBBP6,INKA2,MAPK8IP3,ANKRD24,PARD3" MicroRNA hsa-miR-194-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.15E-06 1.77E-02 4.00E-06 3.68E-05 21 132 "SLC7A14,ARRB2,ARHGEF2,CSNK1E,IP6K1,KBTBD12,SHISA6,LYPLAL1,SH3TC2,RAP1GDS1,ERI2,NCBP3,BTBD3,SNAP25,BDP1,MAPK8IP3,BHLHB9,LAT2,EVI5,PRDM10,SPATA13" MicroRNA hsa-miR-485-3p:Functional MTI Functional MTI miRTarbase 3.17E-06 1.78E-02 4.02E-06 3.70E-05 15 73 "ARID1A,DST,CLTC,RCAN2,TESK2,NBEA,SRCAP,PPARGC1A,MKLN1,NTRK3,KANSL1,PBRM1,SS18,TCF7L2,INTS3" MicroRNA hsa-miR-548ag:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.17E-06 1.78E-02 4.02E-06 3.70E-05 15 73 "CALM1,PTBP2,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PCMT1,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-6884-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.17E-06 1.78E-02 4.02E-06 3.70E-05 15 73 "TAOK1,ATP2A2,MTMR3,TOGARAM2,HIPK3,IDH3B,MYO5A,BEST3,RGR,TRIM67,CLUAP1,NR2E1,TNFRSF1B,NR2C2,ZIC2" MicroRNA hsa-miR-3664-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-06 1.82E-02 4.10E-06 3.78E-05 25 176 "ARID1A,SLC24A4,CDC14B,ZNF583,MAP7,GPR37L1,NDST3,NRXN3,PPP1R16B,YTHDC1,ELMSAN1,SV2B,ZNF585B,CAMKK2,GPR75,GNAS,KCNJ5,PPM1L,NUCB1,PCSK2,PLEC,PPP2R5E,MTMR10,SLC2A5,PSD3" MicroRNA hsa-miR-6851-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.23E-06 1.82E-02 4.10E-06 3.78E-05 11 40 "TMEM132B,SLC24A4,KALRN,ARHGEF2,WASF3,RAB30,VWA5A,MINDY2,PPP3CC,BSDC1,INKA2" MicroRNA hsa-miR-3116:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-06 1.88E-02 4.23E-06 3.90E-05 20 122 "CLK4,HECW2,KIF6,APBB2,CDC14B,CLU,KLHL3,PHC2,ERBB2,ANKMY1,PCYOX1,GPR153,NXPH3,C2orf72,OLR1,PKM,INKA2,MAPK8IP3,ANKRD24,PARD3" MicroRNA hsa-miR-6081:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.34E-06 1.88E-02 4.23E-06 3.90E-05 20 122 "CASKIN1,AK2,ASPH,ENTPD4,PHYHIP,IST1,E2F6,HEYL,PRRC2B,CECR2,KIF5A,LRRC4B,KCNIP3,HIF3A,NACC2,TPM3,RPRM,VAV2,TMEM63C,GAN" MicroRNA hsa-miR-506-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-06 1.88E-02 4.25E-06 3.92E-05 17 92 "LDHD,LONRF1,EN2,ENPP6,DNAJC27,LILRA2,RAPGEF1,SHISA6,KCNN1,STMN1,CHST6,MPP2,NPTX1,DDR2,GPR137C,TPM3,SLC38A1" MicroRNA "TAGAACC,MIR-182:MSigDB" "TAGAACC,MIR-182:MSigDB" MSigDB 3.43E-06 1.93E-02 4.35E-06 4.01E-05 10 33 "BCL2L2,CREM,FAM107B,FAM78B,RBM12,TBR1,AMZ2P1,ZNF532,CNTN2,DOCK9" MicroRNA hsa-miR-3158-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.47E-06 1.95E-02 4.40E-06 4.05E-05 18 102 "ADD1,ESYT2,PHF12,NCOA1,STX16,DCC,APH1A,CHST15,ATOH8,PADI2,CYP27C1,ENPP2,SMARCE1,TMEM178B,UBE2H,VSNL1,SF1,WNK3" MicroRNA hsa-miR-711:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.50E-06 1.96E-02 4.43E-06 4.08E-05 12 48 "TTYH1,ZNF385A,NCAN,FGFR1OP2,DNM2,MRPL10,ECSIT,GPR26,AGBL5,HMX1,SYT1,CYB561A3" MicroRNA hsa-miR-4317:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.50E-06 1.96E-02 4.43E-06 4.08E-05 12 48 "ELFN2,MRO,GPR22,MIER3,EID2B,SESN3,CAMKV,PIK3R1,PNMA8A,ZNF415,RBM26,SLC38A1" MicroRNA hsa-miR-371-3p:mirSVR_highEffct hsa-miR-371-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.64E-06 2.04E-02 4.60E-06 4.24E-05 16 83 "ARHGAP20,SGCE,CA4,CACNA1B,CDO1,TPK1,MALT1,GRIA4,IL6ST,KCNMA1,CDK18,FAT4,SNX22,MYT1L,MCF2L,PDLIM2" MicroRNA hsa-miR-3529-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-06 2.04E-02 4.60E-06 4.24E-05 16 83 "ALDH4A1,SLC2A11,MICAL2,DNAL1,EDN1,TUBD1,EPS8,POLL,TDRKH,DDX19B,MDM4,BEST3,MTRF1L,GDPD1,ZYG11B,TPD52" MicroRNA hsa-miR-6729-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-06 2.04E-02 4.60E-06 4.24E-05 16 83 "CASTOR3,CLDN10,IGDCC3,SEC31B,G3BP2,TOM1,ANKMY1,CACNG2,ATP13A4,NELL2,OPRL1,HMGCLL1,SDK2,WDR37,STAC2,C5orf64" MicroRNA hsa-miR-6895-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-06 2.04E-02 4.60E-06 4.24E-05 16 83 "TXNDC16,C6orf89,PRX,RGS6,APPL1,PHYHIP,TOMM40L,POLR1B,POU3F2,TMEM231,SFPQ,SH3BP2,R3HDM2,AHCYL2,ANKRD24,ITM2C" MicroRNA hsa-miR-937-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-06 2.04E-02 4.60E-06 4.24E-05 16 83 "OGT,UBXN2A,SLC12A6,ANKRD46,RNF165,SCRG1,PLD5,HSPA4L,SHMT2,ST6GAL1,SEPHS1,SPART,FAM168A,CYB561A3,TPD52L2,JMJD1C" MicroRNA hsa-miR-514a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-06 2.09E-02 4.71E-06 4.34E-05 14 65 "IGDCC3,TUBD1,MSANTD4,BVES,KLHL23,MOG,NF1,CAMKV,BCAS3,ZYG11B,NCBP3,R3HDM2,UHRF1BP1L,DIP2A" MicroRNA hsa-miR-8080:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-06 2.09E-02 4.71E-06 4.34E-05 14 65 "TEX22,AK2,MYRF,CD81,BAG4,CACNG2,SEC23B,GCK,GSN,RAB5B,IQSEC3,PRRT2,NACC2,WIPF2" MicroRNA hsa-miR-3659:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-06 2.09E-02 4.71E-06 4.34E-05 14 65 "FOXN3,CLU,TMEM184B,LONRF1,IST1,KATNAL1,ATP13A4,MDM4,PKM,PLEC,FAM126B,MGRN1,NSD1,LRTM2" MicroRNA hsa-miR-6071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-06 2.09E-02 4.71E-06 4.34E-05 14 65 "DCAF8,SV2B,HIPK3,ELAVL3,COQ7,FER,GRIK3,MYCN,NEUROD1,RFX3,NCBP3,ASTN2,TPM1,ZBTB38" MicroRNA hsa-miR-198:Functional MTI Functional MTI miRTarbase 3.79E-06 2.13E-02 4.78E-06 4.40E-05 15 74 "PCDH19,LTBP4,FOXK1,CCNT1,FGFR1,PRRC2B,FUT10,DIDO1,MPP2,NNAT,NTRK3,PBX1,PROX1,ATF7IP,KIAA0930" MicroRNA hsa-miR-203a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.79E-06 2.13E-02 4.78E-06 4.40E-05 15 74 "BRAP,BCL7A,CACNA1A,PTBP2,CD38,CREB5,DOCK4,KCNJ10,XRRA1,ZNF426,NWD1,GANAB,ZNF28,CIAPIN1,WIPF2" MicroRNA hsa-miR-6813-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.79E-06 2.13E-02 4.78E-06 4.40E-05 15 74 "AP1B1,TMEM184B,NCOR2,ANKRD13B,STAMBP,GJB1,PRRC2B,GRID1,PKD1,PKM,KCTD15,MTRF1L,PTPA,SF1,INTS3" MicroRNA hsa-miR-194-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-06 2.20E-02 4.94E-06 4.55E-05 17 93 "AQP6,CDH2,BTF3L4,DNAL1,EIF4G2,FOXM1,SRCAP,HNF4G,TJAP1,ZC3H12B,PTPN13,SETD5,ITSN1,PEX26,SOX5,TJP1,FXR1" MicroRNA hsa-miR-5587-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-06 2.20E-02 4.94E-06 4.55E-05 17 93 "TRMT9B,LRCH2,CDK5R1,RAB3C,HAPLN1,SRARP,CELF1,HBS1L,SEPT9,SESN3,PDE1A,RAD51D,C12orf49,NUBPL,ZBTB43,ZNF621,SGK3" MicroRNA hsa-miR-7162-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-06 2.20E-02 4.94E-06 4.55E-05 17 93 "ABAT,ASTN1,LURAP1,LRRFIP1,LETMD1,TM9SF4,FKTN,LILRA2,RFFL,SHISAL1,NCOA7,GDAP1L1,PSAT1,HSPA4L,SMARCE1,ZFP91,GORASP1" MicroRNA hsa-miR-6730-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-06 2.20E-02 4.94E-06 4.55E-05 17 93 "ARID1A,RNF157,FZD9,CRY2,SRARP,FUT10,TJAP1,PLD5,NUCB1,ZNF827,PKM,PXK,INAVA,ZMAT3,TPM3,UBC,PRDM2" MicroRNA hsa-miR-19b-1-5p:Functional MTI Functional MTI miRTarbase 3.96E-06 2.22E-02 4.99E-06 4.60E-05 19 113 "ARID1A,CACNB2,CD38,DMD,EDN1,CBX1,RASSF8,MDM4,P2RY1,GDPD1,ZSCAN2,FAM161B,SNAP25,ZEB1,FAM200B,ZNF384,STXBP4,ZNF28,ZNF138" MicroRNA hsa-miR-4667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.01E-06 2.25E-02 5.06E-06 4.66E-05 18 103 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,GPR26,TLX1,KCNN3,WBP1L,C12orf49,CLSTN1,LHFPL4,UNC5B,LAT2" MicroRNA hsa-miR-555:PITA hsa-miR-555:PITA_TOP PITA 4.19E-06 2.35E-02 5.28E-06 4.87E-05 13 57 "MAP4K4,NCOR2,PAN3,FOXO3,IPO5,FA2H,SOX5,SATB2,TCF7,FRYL,AHCYL2,TJP1,TPM1" MicroRNA hsa-miR-1302:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.19E-06 2.35E-02 5.28E-06 4.87E-05 13 57 "ARRB2,PPP1R16B,DNAL1,EIF5,METTL21A,STMN1,PKM,FBXW7,PEX26,TPM3,SYNC,SIGLEC10,GAN" MicroRNA hsa-miR-3686:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.28E-06 2.41E-02 5.40E-06 4.97E-05 16 84 "GRAMD1B,MIER1,RASL11B,NIPA1,FOXN3,BTF3L4,SOCS5,DNAJB6,EIF4G2,MRVI1,GRIK4,NPTX2,PBRM1,CHD9,TET1,EPC1" MicroRNA hsa-miR-1972:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.32E-06 2.42E-02 5.44E-06 5.01E-05 20 124 "CSMD2,SLC25A25,RNF157,LTBP4,SHROOM2,YTHDC1,DNAJC27,POLR1B,NCKAP1,RNF165,NUMA1,KCTD15,C11orf49,C12orf49,SH3BP2,R3HDM2,EPN2,ZNF621,SLC37A2,TMEM237" MicroRNA hsa-miR-376a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-06 2.48E-02 5.56E-06 5.12E-05 12 49 "BACH1,SRSF11,BAG4,TUBD1,RAB30,PCDH11X,NUDT21,KPNA5,CLIP1,CHD9,SMARCE1,CBX5" MicroRNA hsa-miR-4275:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-06 2.53E-02 5.68E-06 5.23E-05 14 66 "CDC27,LIN54,EIF4G2,ZNF391,FOXO3,HMGB1,PABPC1L2A,STRN3,UHRF1BP1,SPDL1,RAB5B,LRRC55,EPB41L3,ARL10" MicroRNA hsa-miR-2116-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-06 2.53E-02 5.68E-06 5.23E-05 14 66 "TNRC6C,C1orf52,YTHDC1,RCAN1,GOLT1B,YAF2,ERBB2,STAMBP,NCKAP1L,XRRA1,NCAM2,PDE3A,SH3TC2,RAB3GAP1" MicroRNA hsa-miR-92b*:mirSVR_highEffct hsa-miR-92b*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.51E-06 2.53E-02 5.68E-06 5.23E-05 15 75 "ACHE,PCDH10,SUGT1P4-STRA6LP-CCDC180,TPP1,B4GALNT1,POU3F2,TMEM206,NTNG1,SMARCE1,IFT122,TMEM150C,TPCN2,PRMT8,SPHK2,CASC15" MicroRNA hsa-miR-1290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.51E-06 2.53E-02 5.68E-06 5.23E-05 15 75 "ADD2,TAOK1,BCL7A,CLOCK,PYGO1,TOMM20,MAOB,P2RY1,ATXN1,LRRC55,MPRIP,STAU1,ACSBG1,TPM4,MPPE1" MicroRNA hsa-miR-224-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-06 2.54E-02 5.69E-06 5.24E-05 19 114 "APP,LDHD,EVI5L,CPS1,DYRK1A,FEM1B,DCTN4,SRARP,RTN3,SCML2,PCSK2,CCSER2,TNPO2,FAT3,FIGN,LHPP,TPD52,DHX33,NETO2" MicroRNA hsa-miR-98-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-06 2.54E-02 5.69E-06 5.24E-05 19 114 "SPAG9,C1orf52,MYOM2,COPB2,MYADM,E2F5,SEMA4D,GABRG1,BRPF3,ZNF181,ZNF546,NCOA7,MBNL1,OCIAD1,CNKSR2,RUFY2,DIP2A,GPRIN3,WNK1" MicroRNA hsa-let-7f-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-06 2.54E-02 5.69E-06 5.24E-05 19 114 "SPAG9,C1orf52,MYOM2,COPB2,MYADM,SEMA4D,GABRG1,BRPF3,ZNF181,ZNF546,NCOA7,MBNL1,HNRNPM,OCIAD1,CNKSR2,RUFY2,DIP2A,GPRIN3,WNK1" MicroRNA hsa-miR-1908-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.54E-06 2.55E-02 5.71E-06 5.26E-05 21 135 "DPF1,PTCHD1,PDZD4,PRX,ARHGDIA,EVI5L,ZNF385A,MICAL2,MYADM,MTSS1L,NEUROD2,NRGN,PACSIN1,C12orf49,PTGR2,SBF1,SLC1A2,PEX26,WBP2,VGF,ZNF154" MicroRNA hsa-miR-8087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.55E-06 2.56E-02 5.72E-06 5.27E-05 17 94 "LDHD,CACNB2,CNTNAP2,STARD3NL,TLR7,C1orf61,CELF1,PACSIN2,KCNJ10,KPNA5,ARHGAP12,TCP11L1,PEX26,TMEM178B,TSC1,ZNF138,ZBTB38" MicroRNA hsa-miR-4263:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.55E-06 2.56E-02 5.72E-06 5.27E-05 17 94 "FZD9,ABCD2,SFMBT2,PTBP2,CRY2,SUCO,SARAF,GATM,GCK,ZHX1,HNF4G,NEGR1,KITLG,NEUROD1,PKM,TET1,RGMB" MicroRNA hsa-miR-542-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-06 2.61E-02 5.83E-06 5.37E-05 10 34 "ZNF385A,SEC16A,GRIN3A,EGFR,TBR1,WASF3,TNPO2,EMID1,MPRIP,SH3GLB2" MicroRNA hsa-miR-3654:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-06 2.61E-02 5.83E-06 5.37E-05 10 34 "ESYT2,NLGN4X,TMEM184B,HIPK3,SAMD5,SESN3,KSR2,PTPA,MSANTD2,GPRIN3" MicroRNA hsa-miR-33a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.64E-06 2.61E-02 5.83E-06 5.37E-05 22 146 "XKR4,C1QTNF3,CACNA1A,CLTA,KIAA0408,MATR3,CEP170,GUCD1,CPEB2,CAMSAP1,FYB1,MALT1,TNRC6A,GNAL,DIDO1,SESN3,FIGN,RHBDL3,TCF12,ZMAT3,METTL3,RPL7L1" MicroRNA hsa-miR-4285:mirSVR_highEffct hsa-miR-4285:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.79E-06 2.69E-02 6.01E-06 5.53E-05 8 21 "RTL9,KCNAB3,OLIG1,SYT3,GLI2,SLC2A6,PTPRE,PPIL6" MicroRNA hsa-miR-139-3p:PITA hsa-miR-139-3p:PITA_TOP PITA 4.79E-06 2.69E-02 6.01E-06 5.53E-05 8 21 "GRM5,MSI1,PLP1,SOX8,FUZ,CAMTA2,TMOD1,POLR3H" MicroRNA hsa-miR-6890-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.89E-06 2.75E-02 6.14E-06 5.66E-05 20 125 "C6orf89,CPNE5,CACNG1,COL9A2,TBPL1,KIAA0586,POLL,GRIK2,KCNH1,GPR155,MDM4,MPP2,PAK3,ZNF426,GDPD1,C12orf49,PTGR2,CLUAP1,PUM2,ZNF24" MicroRNA hsa-miR-7159-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.03E-06 2.82E-02 6.31E-06 5.81E-05 16 85 "TNRC6C,RIMS4,ZNF585B,PNMA2,KCNMB4,NEGR1,IGF1,ZNF678,MYBPC1,NPTX1,POLG,TET1,SOX1,SYT4,TCF7L2,FBXL16" MicroRNA hsa-miR-148a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.03E-06 2.82E-02 6.31E-06 5.81E-05 16 85 "CACNA1A,C1orf52,COL9A2,CST3,BOC,MTX3,SH3GLB1,GPR61,RCAN2,APC2,SCML2,AFF2,FUT10,CCDC80,PDPK1,TNS1" MicroRNA hsa-miR-4463:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.03E-06 2.82E-02 6.31E-06 5.81E-05 16 85 "CC2D2A,DOCK11,KIAA0586,PLEKHM1,EGR3,GRM3,GPR173,SPATA6,PTPA,PTAFR,RTKN,SLC6A9,YPEL4,SEPT8,WNK3,FXR1" MicroRNA hsa-miR-1183:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.03E-06 2.82E-02 6.31E-06 5.81E-05 16 85 "ZNF608,HECTD1,IST1,FAM107B,PLEKHA1,TMEM164,SGIP1,NPTN,CELF1,HMGB1,DDR2,PDPK1,HSPA4L,ZHX3,ERBIN,AMACR" MicroRNA hsa-miR-6782-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-06 2.89E-02 6.46E-06 5.95E-05 13 58 "MTX3,DPYSL2,CELSR3,TNRC6A,KCNN3,ADAM22,PFKFB3,UBR7,ACER3,RXRA,RUFY2,SLC6A8,HPS4" MicroRNA hsa-miR-6797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-06 2.89E-02 6.46E-06 5.95E-05 13 58 "ZNF445,FBXL5,STARD3NL,EIF1,NEURL4,TNRC6A,BACH2,PDE3A,FNDC9,SSBP2,KCNK12,WNK1,WNK3" MicroRNA hsa-miR-370-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-06 2.89E-02 6.46E-06 5.95E-05 13 58 "ABCF1,DIRAS1,FOXN3,CRY2,ELMSAN1,MAP2,SMOX,RPS6KA2,WDTC1,KLHL4,CBX5,ZNF154,URM1" MicroRNA hsa-miR-4772-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.15E-06 2.89E-02 6.46E-06 5.95E-05 13 58 "KIF6,WAC,SUCO,SMC2,NCKAP1,GLUL,SLC22A23,PRRT2,ALG9,PEAR1,CLUAP1,WBP2,TSN" MicroRNA hsa-miR-887:mirSVR_highEffct hsa-miR-887:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-06 2.97E-02 6.62E-06 6.09E-05 17 95 "ADD3,ASTN1,CALM1,CCPG1,NCOR2,NELFCD,TRAF3IP2,GAP43,GCNT2,GATD1,MDM4,PTPRO,SAFB,SCN8A,PREX2,P2RY12,HNRNPA3" MicroRNA hsa-miR-195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-06 2.97E-02 6.62E-06 6.09E-05 17 95 "BID,CBS,CCNT1,CLCN3,CLTC,ABCG2,ACBD5,PREPL,SH3GLB1,UBE2E3,RBBP6,ERBIN,TUBB2A,CCDC14,TBC1D15,VSNL1,CADM2" MicroRNA hsa-miR-139-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.31E-06 2.98E-02 6.65E-06 6.13E-05 18 105 "TEX22,NLGN4X,TMEM170A,DNAL1,TUBD1,SLC43A2,ZNF585B,ZNF589,FAM184B,GFRA1,CNDP1,NFIX,PDGFRA,SMIM7,PKIA,SETD5,USP22,SSBP2" MicroRNA hsa-miR-9-3p:Functional MTI Functional MTI miRTarbase 5.31E-06 2.98E-02 6.65E-06 6.13E-05 18 105 "B4GALT6,C2CD2,KIAA0408,DMD,EPB41L1,ATP13A4,SRCAP,ELOVL5,RBPJ,P2RX7,ABCB1,PPARA,MAPK3,TUG1,KLHL11,SLC25A36,HSPA4L,TPD52" MicroRNA hsa-miR-6852-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-06 3.01E-02 6.70E-06 6.17E-05 15 76 "SERPINA3,ATP2B3,UBXN2A,GCK,NR3C1,PTPRT,ZNF678,KCNJ10,PKM,C11orf49,ZMAT3,TNFRSF1B,ZNF154,PMEPA1,MVB12B" MicroRNA hsa-miR-653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-06 3.01E-02 6.70E-06 6.17E-05 15 76 "AK2,DCAF5,BAG4,AASS,LUZP2,IL6R,SMAD9,PAX6,CLIP1,ANKRD6,SEPHS1,DOK6,TSN,TUB,UBC" MicroRNA hsa-miR-4254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-06 3.01E-02 6.70E-06 6.17E-05 15 76 "CLU,RIMS4,UBXN2A,ABCC5,PHC2,EFNA3,ANKMY1,NSG2,CRCP,HMX1,PKM,STX1B,AGTPBP1,WBP2,WIPF2" MicroRNA hsa-miR-4732-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-06 3.01E-02 6.70E-06 6.17E-05 15 76 "RGS11,ZNF385A,TACC2,SMC2,NCKAP1,NEGR1,SLC35G1,CYP27C1,MAT2A,DDR2,KSR2,HMGCLL1,UBR7,ZNF177,DHX33" MicroRNA hsa-miR-6817-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.36E-06 3.01E-02 6.70E-06 6.17E-05 15 76 "SLC7A14,ARSE,REPS2,QKI,BOC,EDN1,EDN3,EPB41,CELF1,RAPGEF1,ZNF546,PLCL1,RXRA,TMEM136,ZNF106" MicroRNA hsa-miR-10a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-06 3.05E-02 6.79E-06 6.26E-05 14 67 "ACLY,BTRC,CDC27,CDR1,DBN1,IRAK4,RGS17,HBS1L,IGF1,RCOR3,NR2C2,UBE2H,ZNF24,ZBTB38" MicroRNA hsa-miR-27b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-06 3.05E-02 6.79E-06 6.26E-05 14 67 "ADCYAP1R1,SLC24A4,TAOK1,TRMT9B,CDH2,SV2B,UFM1,SNX10,PRR5L,KIF27,TRA2B,FBXO11,TRPS1,PHTF2" MicroRNA hsa-miR-499a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-06 3.05E-02 6.79E-06 6.26E-05 14 67 "PLEKHG5,CAPRIN2,CACNA1B,LIN54,DNAH9,MAMLD1,FEM1B,SRRM1,LIFR,NAT8L,MDM4,MEF2C,FXYD6,FIGN" MicroRNA hsa-miR-4678:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.44E-06 3.05E-02 6.79E-06 6.26E-05 14 67 "PITPNC1,E2F6,PLEKHA1,FREM1,GRB10,IL6R,LIFR,MDM4,PPP1R1A,WLS,BTBD3,TAB2,SYT1,RPRM" MicroRNA hsa-miR-1298-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 12 50 "ZNF385A,PHF19,UFM1,CRCP,GLUL,GRID1,MAT2A,MYBPC1,PPP1R1A,PTPRE,PEX26,TMPO" MicroRNA hsa-miR-3689b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 12 50 "SDC3,ZBED3,CELF1,ZNF181,MDM4,CLIP1,CSRNP3,FAM126B,SMOC1,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-3689e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 12 50 "SDC3,ZBED3,CELF1,ZNF181,MDM4,CLIP1,CSRNP3,FAM126B,SMOC1,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-3689a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 12 50 "SDC3,ZBED3,CELF1,ZNF181,MDM4,CLIP1,CSRNP3,FAM126B,SMOC1,TPCN2,BCL2L13,HNRNPA3" MicroRNA hsa-miR-4709-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 20 126 "ABAT,ANK1,USP37,APP,PTCH2,AP1M1,CPS1,PLXNA4,DCAF8,ST8SIA3,C1orf61,RAPGEF1,GRID1,MDM4,CNNM2,ZSCAN2,MSANTD2,WRN,ZNF138,STOX2" MicroRNA hsa-miR-562:Functional MTI Functional MTI miRTarbase 5.54E-06 3.11E-02 6.92E-06 6.37E-05 20 126 "CDC14B,CCNT1,FOXN3,CREM,EIF4G2,RGS17,SLC43A2,EYA1,TRMO,ZBED3,TXNL4A,KIF3A,KAT7,FICD,PDE3B,PSAT1,PTAFR,PGBD4,SOX6,WWC1" MicroRNA hsa-miR-7113-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-06 3.27E-02 7.26E-06 6.69E-05 22 148 "C6orf89,BCL7A,FMNL3,TMEM184B,IPCEF1,ELMSAN1,KLHL3,SCML2,GRK4,MDFI,NFIX,NUMA1,RNH1,HES6,MAPKBP1,NFASC,TMEM178B,SIN3B,TMEM151B,PCDHA6,TSPAN11,MPPE1" MicroRNA hsa-miR-6811-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.93E-06 3.33E-02 7.39E-06 6.81E-05 25 182 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,ZFYVE9,AKAP5,GREB1,DNAL1,YTHDC1,TRAF3IP2,RAB30,IGF1,KCNJ5,ZC3H12B,PEX2,NCBP3,SH3BP2,INAVA,UNC5B,SMOC1,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA hsa-miR-4700-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.10E-06 3.43E-02 7.60E-06 7.00E-05 18 106 "PPFIA4,BMP7,CBS,USP2,ZNF385A,RGS6,IP6K1,KLHL3,RASA4,GPR26,TLX1,KCNN3,WBP1L,C12orf49,CLSTN1,LHFPL4,UNC5B,LAT2" MicroRNA hsa-miR-548av-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-06 3.44E-02 7.62E-06 7.02E-05 17 96 "USP37,NUMB,BAG4,DNAL1,E2F6,FOXO3,PACSIN2,ELOVL5,HMGB1,PDYN,CRLS1,KANSL1,RAB5B,GSE1,TMEM136,SMARCAD1,MFF" MicroRNA hsa-miR-892c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-06 3.44E-02 7.62E-06 7.02E-05 17 96 "TAOK1,CDC25B,SEMA3D,EN2,EPS8,LILRA2,SHISA6,KCNN1,KCNN3,STMN1,NPTX1,DDR2,PCSK1,RFX3,ZNF189,SMARCAD1,SLC38A1" MicroRNA hsa-miR-6871-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.12E-06 3.44E-02 7.62E-06 7.02E-05 17 96 "DDR1,DIRAS1,TOGARAM2,FEM1B,SH3GLB1,GOLGA7,SYNPO,NASP,PDPK1,GLDN,SLC30A10,SGK1,ZC3H4,SLC37A2,CLASP1,ZNF45,GAN" MicroRNA hsa-miR-1269a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.20E-06 3.48E-02 7.73E-06 7.12E-05 10 35 "ESYT2,E2F6,EN2,CAB39,RNF165,OPHN1,KCTD15,FITM2,SOX6,MYO18A" MicroRNA hsa-miR-6744-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-06 3.49E-02 7.73E-06 7.12E-05 24 171 "ZNF578,ARHGDIA,MTMR9,COL9A2,ELMSAN1,TESK2,GPD1,HAS2,HMGB1,PAK3,PIK3C2A,ZNF426,C12orf49,ZNF568,FOXRED2,DRAXIN,HSPA4L,CLUAP1,VAMP1,GPRIN3,ZNF34,CBX5,ZNF70,HNRNPA3" MicroRNA hsa-miR-4757-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.21E-06 3.49E-02 7.73E-06 7.12E-05 24 171 "ZNF578,ARHGDIA,MTMR9,COL9A2,ELMSAN1,TESK2,GPD1,HAS2,HMGB1,PAK3,PIK3C2A,ZNF426,C12orf49,ZNF568,FOXRED2,DRAXIN,HSPA4L,CLUAP1,VAMP1,GPRIN3,ZNF34,CBX5,ZNF70,HNRNPA3" MicroRNA hsa-miR-6076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-06 3.54E-02 7.84E-06 7.22E-05 13 59 "ZNF445,FBXL5,STARD3NL,EIF1,NEURL4,TNRC6A,BACH2,PDE3A,FNDC9,SSBP2,KCNK12,WNK1,WNK3" MicroRNA hsa-miR-1910-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-06 3.54E-02 7.84E-06 7.22E-05 13 59 "USP37,DNAH17,ZNF583,TNK2,MTHFD2,PRRC2B,NASP,KCNK10,ATXN1,SLC1A2,KIF21B,TMEM151B,JPH3" MicroRNA hsa-miR-6828-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.30E-06 3.54E-02 7.84E-06 7.22E-05 13 59 "CACNA1A,DCAF8,HIPK3,COQ7,GSN,NEUROD1,RFX3,UEVLD,ASTN2,GPRIN3,TPM1,VLDLR,ZBTB38" MicroRNA hsa-miR-8073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-06 3.63E-02 8.04E-06 7.41E-05 21 138 "SMIM17,PDXK,ARHGDIA,DNAH17,BCL2L2,MTMR3,CCNT1,UFM1,ZNF234,HAS2,KCNJ11,SEPT4,PTAFR,RIMKLA,SLC1A7,KANSL3,SLC8A3,FNBP1,UNC5B,PRRC2C,ZNF70" MicroRNA hsa-miR-3656:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.53E-06 3.67E-02 8.12E-06 7.48E-05 14 68 "LTBP4,REPS2,GAPVD1,RASSF2,GNG4,KAT7,HMX1,KCNK3,ADAMTS17,SSBP2,ZNF708,ZNF154,PRDM2,EVI5" MicroRNA hsa-miR-802:Functional MTI Functional MTI miRTarbase 6.53E-06 3.67E-02 8.12E-06 7.48E-05 14 68 "KIAA1549L,COL4A5,BTF3L4,FRY,RTN3,SYNCRIP,TJAP1,STX1B,TJP1,RPL7L1,SF1,ZNF711,ZNF708,PHTF2" MicroRNA hsa-miR-6744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.53E-06 3.67E-02 8.12E-06 7.48E-05 14 68 "GAS7,CDC25B,CPS1,PLXNA4,ST18,DNAL1,ING4,FAM120B,RAPGEF1,GPR137C,C1orf109,NKAIN1,FAM102A,NMNAT2" MicroRNA hsa-miR-613:Functional MTI Functional MTI miRTarbase 6.88E-06 3.86E-02 8.55E-06 7.87E-05 16 87 "ANK1,CLCN3,RIMS4,MATR3,MYEF2,ABI2,BSCL2,COQ7,ZBED3,STAMBP,FYB1,NUDT21,DDX19B,FNDC3A,FGD4,WBP2" MicroRNA hsa-miR-1278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.91E-06 3.88E-02 8.59E-06 7.91E-05 12 51 "RTTN,PYGO1,IST1,PLEKHA1,TMEM164,SARAF,RNPS1,GRIK3,HSP90AA1,BCAS3,SETD5,SEMA6D" MicroRNA hsa-miR-4666a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.99E-06 3.93E-02 8.68E-06 7.99E-05 18 107 "ARID1A,SPAG9,MYOM2,COPB2,TMTC1,RCAN2,SEMA4D,BRPF3,DIPK1C,ZNF181,ZNF546,MBNL1,OCIAD1,CNKSR2,RUFY2,SON,TNS1,WNK1" MicroRNA hsa-miR-2909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.99E-06 3.93E-02 8.68E-06 7.99E-05 11 43 "TXNDC16,SLC22A6,APPL1,RASA4,TOMM40L,UBE2QL1,SH3TC2,ZMAT4,RTKN,NFASC,NEK4" MicroRNA "GCAAGAC,MIR-431:MSigDB" "GCAAGAC,MIR-431:MSigDB" MSigDB 6.99E-06 3.93E-02 8.68E-06 7.99E-05 11 43 "BTF3L4,NRG2,CEP170,EPB41L1,LRRC37A6P,NRCAM,DHX30,CAMTA1,TBX15,LAMP5,NETO1" MicroRNA hsa-miR-365a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.08E-06 3.98E-02 8.79E-06 8.09E-05 20 128 "ESYT2,ATP1B3,ENTPD6,ZMYM4,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,RAPGEF1,GRIK3,KCNK3,NUCB1,IGSF9B,ARHGAP26,ATP11A,TPM3,LAT2,CFAP298" MicroRNA hsa-miR-6864-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-06 4.21E-02 9.29E-06 8.56E-05 15 78 "TMCC3,HCN2,CA8,CD81,FRMPD4,DUSP9,RAPGEF1,LIFR,MAT2A,CCDC80,CLDN11,EPB41L4B,PTPA,SP2,MEAF6" MicroRNA hsa-miR-183-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.61E-06 4.27E-02 9.44E-06 8.70E-05 19 118 "OSBPL8,PROM1,CLCN3,CHST15,GABRB1,NEGR1,IBA57,LAMA2,N6AMT1,SH3TC2,BDP1,FNBP1,TMEM136,HEY2,KCNT2,ZNF138,TFIP11,XKR7,ADAMTS9" MicroRNA hsa-miR-6779-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.67E-06 4.31E-02 9.52E-06 8.77E-05 13 60 "EPS15L1,GAPVD1,TBC1D5,EPB41,NCKAP1L,KCNJ11,DDR2,KCNK10,TNPO2,TMEM136,SZT2,TPM3,TMEM63C" MicroRNA hsa-miR-6872-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.98E-06 4.48E-02 9.90E-06 9.12E-05 20 129 "RAB3C,RNF14,HINFP,DNAJB6,TBC1D16,FKTN,PCYOX1,PDLIM5,TRAF3IP2,NKD1,TNPO2,ZDHHC14,ZYG11B,PEX26,IGSF9B,SLC37A2,GPRIN3,BCL2L13,CFAP298,LINC00632" MicroRNA hsa-miR-4683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.99E-06 4.49E-02 9.91E-06 9.13E-05 18 108 "SLC24A4,SMIM17,UBXN2A,DYRK1A,FARSB,GLUL,PRRC2B,SHISA6,OLA1,FAT3,RAB5B,HES6,SLC8A1,MYH15,SIK3,SSBP2,TUBB2A,GDPD5" MicroRNA hsa-miR-504-5p:Functional MTI Functional MTI miRTarbase 7.99E-06 4.49E-02 9.91E-06 9.13E-05 18 108 "ZNF445,CNOT8,CRY2,DRD1,NSG2,KBTBD12,MAT2A,P2RY13,PDE4A,PKD1,PSAT1,PRRT2,CSRNP3,ZC3H4,TRIM2,CLASP1,TPM4,NR2C2" MicroRNA hsa-miR-6765-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.15E-06 4.58E-02 1.01E-05 9.31E-05 17 98 "KLHL32,CEP126,LTBP4,CCNT1,C1orf52,RIMS4,PCYOX1,KIF3A,KAT7,ZNF491,IGF1,A2ML1,MSANTD2,SEPHS1,FAM208A,EVI5,URM1" MicroRNA hsa-miR-337-5p:PITA hsa-miR-337-5p:PITA_TOP PITA 8.20E-06 4.60E-02 1.02E-05 9.36E-05 10 36 "ARNTL,MARK4,CPEB2,SESN3,SNX22,SGK1,NLGN1,SLC44A1,ZBTB38,WNK1" MicroRNA hsa-miR-7705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.58E-06 4.82E-02 1.06E-05 9.78E-05 12 52 "SOCS5,KLHL3,GUCY1A2,INSYN1,CYP27C1,GPSM2,CEP97,NCBP3,KIF21A,KLHL7,ZMAT3,CSDE1" MicroRNA hsa-miR-3162-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.58E-06 4.82E-02 1.06E-05 9.78E-05 12 52 "RGS6,CTNND1,TM9SF4,RASA4,GOLGA7,ANKFY1,NR3C1,SLC25A36,RTKN,NEK4,ZNF34,FAM198A" MicroRNA hsa-miR-6505-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.58E-06 4.82E-02 1.06E-05 9.78E-05 12 52 "TMEM132B,ARNTL,CCPG1,HIPK3,INSYN1,KCTD6,THYN1,PBX1,MYH15,LIMCH1,NECAB1,CBX5" MicroRNA hsa-miR-4663:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.81E-06 4.95E-02 1.09E-05 1.01E-04 15 79 "TTYH1,RGS11,KMT2C,UBXN2A,KIAA0408,IST1,TOMM20,SV2B,EPB41L4B,MTMR10,QDPR,PLEKHB2,CHD9,PEX26,VAMP1" MicroRNA hsa-miR-3688-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.81E-06 4.95E-02 1.09E-05 1.01E-04 15 79 "ARID1A,PHF12,LDHD,SYNJ2,CFAP410,BTF3L4,ENTPD4,CELF1,PARD3B,ZNF678,MYCN,RAP1GDS1,THRA,RGMB,TIGD6" MicroRNA hsa-miR-451:PITA hsa-miR-451:PITA_TOP PITA 8.89E-06 4.99E-02 1.10E-05 1.01E-04 11 44 "DDX3Y,MAML1,EVL,CAB39,POU3F2,MINDY2,SETD5,MPRIP,AKTIP,ZIC3,EMSY" MicroRNA hsa-miR-1915-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.30E-06 5.22E-02 1.15E-05 1.06E-04 13 61 "TNRC6C,CALM1,NRXN3,TPP1,TOMM20,ABI2,CRCP,TLX1,SHISA6,MAPT,TRIM67,ZBTB43,UBE2H" MicroRNA hsa-miR-4298:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.30E-06 5.22E-02 1.15E-05 1.06E-04 13 61 "ARRB2,PPP1R16B,DNAL1,EIF5,METTL21A,STMN1,PKM,FBXW7,PEX26,TPM3,SYNC,SIGLEC10,GAN" MicroRNA hsa-miR-675-5p:Functional MTI Functional MTI miRTarbase 9.31E-06 5.23E-02 1.15E-05 1.06E-04 14 70 "ESYT2,FOXK1,REPS2,DIS3L,AKAP5,MICAL2,HDAC4,CALN1,ATP8A2,MITF,NUMA1,FITM2,INAVA,NMNAT2" MicroRNA hsa-miR-548ba:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-06 5.23E-02 1.15E-05 1.06E-04 14 70 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PCMT1,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-615-5p:Functional MTI Functional MTI miRTarbase 9.31E-06 5.23E-02 1.15E-05 1.06E-04 14 70 "ELFN2,CPNE5,IP6K1,FLYWCH1,KCNH1,COMMD5,NFIX,TBC1D25,ZNF426,HSD11B1L,RAP1GAP2,ARC,AGTPBP1,THRA" MicroRNA hsa-miR-5000-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-06 5.23E-02 1.15E-05 1.06E-04 14 70 "ADAR,KALRN,C1orf52,PREPL,ANKRD46,EIF5,SALL3,TCERG1,TNRC6A,PRRC2B,ZNF678,MYH14,BTBD3,SLC8A3" MicroRNA hsa-miR-6126:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.31E-06 5.23E-02 1.15E-05 1.06E-04 14 70 "TMCC3,ARRB1,CANX,CD81,AKAP5,IRAK3,LIFR,CCDC80,CLDN11,PMP22,MAPKBP1,SATB2,MEAF6,ZNF74" MicroRNA hsa-miR-5691:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-05 5.68E-02 1.25E-05 1.15E-04 20 131 "AS3MT,ISPD,TBRG4,DBT,ZC3H11A,GOLGA7,ELAVL2,CDHR1,GSN,GPR155,MKLN1,CD200,SEPT4,ELMOD1,HSPA4L,KLHL7,ADAMTS17,ZNF74,LYPD6,ZNF154" MicroRNA hsa-miR-217:Functional MTI Functional MTI miRTarbase 1.03E-05 5.81E-02 1.28E-05 1.18E-04 15 80 "INSYN2B,ZNF583,SRSF11,HINFP,OSBPL3,DNAL1,MTX3,FOXO3,TCERG1,BACH2,ROBO1,HSPA4L,TCF7L2,SIRT1,FXR1" MicroRNA hsa-miR-593-5p:Functional MTI Functional MTI miRTarbase 1.03E-05 5.81E-02 1.28E-05 1.18E-04 15 80 "ADCY5,SLC24A4,CDC25B,PITPNM3,CELF1,PRUNE2,NR3C1,RIMKLA,RUFY2,ANKRD36,MPRIP,PRRC2C,TRPS1,RPL7L1,MFF" MicroRNA hsa-miR-614:PITA hsa-miR-614:PITA_TOP PITA 1.05E-05 5.88E-02 1.29E-05 1.19E-04 7 17 "GAS7,NRG2,EML4,SCRT2,CPEB4,PLCB1,TCF4" MicroRNA hsa-miR-1280:PITA hsa-miR-1280:PITA_TOP PITA 1.05E-05 5.88E-02 1.29E-05 1.19E-04 7 17 "NRXN2,CTNND1,DLG2,FXYD7,NFIX,CAMKV,CDK19" MicroRNA hsa-miR-483-5p:PITA hsa-miR-483-5p:PITA_TOP PITA 1.05E-05 5.91E-02 1.30E-05 1.20E-04 8 23 "NDRG2,SLC12A5,ALCAM,CPNE5,RNF165,NFIX,MAPK3,SOX11" MicroRNA hsa-miR-4427:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "UBXN2A,ERBB2,RASSF8,ZNF491,TLX1,N6AMT1,PEX2,TMEM100,MCMBP,FNBP1,PSD3,SMUG1" MicroRNA hsa-miR-5681b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "API5,FOXK1,DLGAP3,TMEM184B,NCKAP1,MIER3,ZNF426,ZNF793,CNKSR2,TAB2,NSD2,MPPE1" MicroRNA hsa-miR-4765:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "SEMA4G,ARHGDIA,ADGRG1,IST1,RPS6KL1,SLC6A17,ZFYVE21,PMP22,RBBP8,CAMSAP2,TUBB2A,TMEM63C" MicroRNA "CCATCCA,MIR-432:MSigDB" "CCATCCA,MIR-432:MSigDB" MSigDB 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "HECW2,PCDH10,SPTBN4,DYNLL1,CALN1,GPM6A,NTRK3,PPM1E,CHD9,SOX2,CAMTA1,SZT2" MicroRNA hsa-miR-3682-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "ZBTB10,ATP1B3,SRSF11,FEZ2,ZSCAN23,FEM1B,MRVI1,PRRC2B,HMGCR,KCNA4,LAT2,PAK5" MicroRNA hsa-miR-515-3p:Functional MTI Functional MTI miRTarbase 1.06E-05 5.94E-02 1.30E-05 1.20E-04 12 53 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,WAC,FLT1,PTPRT,AFF1,ADAM22,ZC3H12B,UEVLD" MicroRNA hsa-miR-520d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-05 6.04E-02 1.32E-05 1.22E-04 23 165 "MTA3,ST3GAL5,COPB2,GUCD1,SV2B,EDN1,STARD3NL,CACNG2,TACC2,GABRB3,RNPS1,NR3C1,ZIC5,PFKP,PDZRN4,PSD,RNASEL,ROBO1,ZNF415,FAM126B,NXT2,TMEM178B,SMARCAD1" MicroRNA hsa-miR-3180:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-05 6.05E-02 1.33E-05 1.22E-04 17 100 "DPF1,AMH,FOXK1,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,NEUROD2,NRGN,OLR1,FXYD1,SBF1,MAPK8IP3,WSCD1,TPM3" MicroRNA hsa-miR-3180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-05 6.05E-02 1.33E-05 1.22E-04 17 100 "DPF1,AMH,FOXK1,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,NEUROD2,NRGN,OLR1,FXYD1,SBF1,MAPK8IP3,WSCD1,TPM3" MicroRNA hsa-miR-16-1-3p:Functional MTI Functional MTI miRTarbase 1.08E-05 6.05E-02 1.33E-05 1.22E-04 17 100 "FOXN3,CPS1,MATR3,GOLGA7,FABP7,ACSL4,TRMO,KITLG,MKLN1,GNG2,PKN2,ATXN1,ATF7IP,STAU1,CBX5,ZNF70,RNF146" MicroRNA hsa-miR-7855-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-05 6.06E-02 1.33E-05 1.22E-04 16 90 "CLU,PPP1R16B,DNAH9,ANKFY1,POLL,SHISAL1,NOS1,KANSL1,SLC25A36,C12orf49,SCN4B,EPN2,EMC1,ACSBG1,ZNF70,GAN" MicroRNA hsa-miR-548ai:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.11E-05 6.21E-02 1.36E-05 1.25E-04 14 71 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PCMT1,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-3181:mirSVR_highEffct hsa-miR-3181:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.12E-05 6.31E-02 1.38E-05 1.27E-04 13 62 "UNC5A,SUGT1P4-STRA6LP-CCDC180,CDC14B,ARHGEF7,CPS1,PREPL,RASA4,FCGRT,EXOSC10,MASP1,PTPRE,FAM192A,HEPACAM" MicroRNA hsa-miR-3126-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-05 6.31E-02 1.38E-05 1.27E-04 11 45 "CDC27,PHF19,DBT,GRID1,MAT2A,PPP1R1A,PTPRE,DPF2,PEX26,SLC6A8,TMPO" MicroRNA hsa-miR-4727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-05 6.31E-02 1.38E-05 1.27E-04 11 45 "UBXN2A,ZC3H11A,FARSB,GATM,RAB30,HMGB1,PKM,SMOX,ZNF621,DDHD2,ZXDA" MicroRNA hsa-miR-328-3p:Functional MTI Functional MTI miRTarbase 1.14E-05 6.37E-02 1.40E-05 1.29E-04 20 132 "TMEM132B,APP,DYNLL1,ARHGEF25,ARHGEF2,ABCG2,POM121,TCERG1,HMGB1,HNRNPK,KCNH2,VWA5A,MAP4,MMP16,PKM,TRIM67,SMARCE1,INKA2,UBTF,NUP214" MicroRNA hsa-miR-6805-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-05 6.37E-02 1.40E-05 1.29E-04 20 132 "AS3MT,ISPD,TBRG4,DBT,ZC3H11A,GOLGA7,ELAVL2,CDHR1,GSN,GPR155,MKLN1,CD200,SEPT4,ELMOD1,HSPA4L,KLHL7,ADAMTS17,ZNF74,LYPD6,ZNF154" MicroRNA hsa-miR-487b:PITA hsa-miR-487b:PITA_TOP PITA 1.17E-05 6.55E-02 1.43E-05 1.32E-04 9 30 "SDE2,SNAP91,GRM3,RNF165,CLIP1,ITSN1,KAT6B,ZIC1,PAK5" MicroRNA hsa-miR-199b-5p:Functional MTI Functional MTI miRTarbase 1.18E-05 6.64E-02 1.45E-05 1.34E-04 18 111 "DDR1,ERBB2,GRB10,DDX19B,KIT,XRRA1,TMOD2,A2ML1,POLR2F,ZNF844,SLC8A1,ZFP1,SNAP25,ZNF415,SIRT1,DDHD1,PLPP4,ZNF195" MicroRNA hsa-miR-638:PITA hsa-miR-638:PITA_TOP PITA 1.19E-05 6.65E-02 1.46E-05 1.34E-04 6 12 "SPEG,STARD10,MIER3,WDR47,SOX2,CELF4" MicroRNA hsa-miR-551b:PITA hsa-miR-551b:PITA_TOP PITA 1.19E-05 6.65E-02 1.46E-05 1.34E-04 6 12 "NEURL1,CTIF,ERBB4,PTK2,TMEM255A,PJA1" MicroRNA hsa-miR-551a:PITA hsa-miR-551a:PITA_TOP PITA 1.19E-05 6.65E-02 1.46E-05 1.34E-04 6 12 "NEURL1,CTIF,ERBB4,PTK2,TMEM255A,PJA1" MicroRNA hsa-miR-541-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-05 6.68E-02 1.46E-05 1.34E-04 23 166 "CACNA1E,PHF19,ELMSAN1,APH1A,ERBB2,ANKFY1,CRCP,GLI2,METTL21A,FXYD6,ZC3H12B,NFIX,GPR173,FXYD1,FOXRED2,TRIM67,SLIT1,SPART,TMEM178B,CLASP1,CRTC1,RICTOR,ITM2C" MicroRNA hsa-miR-433-3p:Functional MTI Functional MTI miRTarbase 1.21E-05 6.80E-02 1.49E-05 1.37E-04 15 81 "MTMR9,BBS2,LONRF2,ENTPD4,EDN1,PLEKHA1,MBNL1,MDM4,MAPK8,ATXN1,CHD9,NUBPL,FAM126B,ERBIN,KLHL4" MicroRNA hsa-miR-1204:mirSVR_highEffct hsa-miR-1204:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.21E-05 6.80E-02 1.49E-05 1.37E-04 15 81 "SLC12A5,CFL2,TM9SF4,SEZ6L2,RACK1,RND1,CLASRP,FAM95B1,DNHD1,PDE3A,SLC25A23,PTPRG,ELMO2,EML6,UBE3B" MicroRNA hsa-miR-6846-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-05 6.94E-02 1.52E-05 1.40E-04 17 101 "BCL7A,CBARP,CLU,CS,ABCC5,MRNIP,RAPGEF1,TJAP1,PDE4A,SMOX,POLR2F,SARS,SBF1,STX1A,THRA,NACC2,WBP2" MicroRNA hsa-miR-6816-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-05 6.94E-02 1.52E-05 1.40E-04 17 101 "DPF1,AMH,FOXK1,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,NEUROD2,NRGN,OLR1,FXYD1,SBF1,MAPK8IP3,WSCD1,TPM3" MicroRNA hsa-miR-6848-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-05 6.94E-02 1.52E-05 1.40E-04 17 101 "BCL7A,CBARP,CLU,CS,ABCC5,MRNIP,RAPGEF1,TJAP1,PDE4A,SMOX,POLR2F,SARS,SBF1,STX1A,THRA,NACC2,WBP2" MicroRNA hsa-miR-6514-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.24E-05 6.96E-02 1.52E-05 1.40E-04 24 178 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,ZFYVE9,AKAP5,GREB1,DNAL1,YTHDC1,TRAF3IP2,IGF1,KCNJ5,OLR1,PEX2,RAB5B,NCBP3,SH3BP2,INAVA,UNC5B,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA hsa-miR-206:Functional MTI Functional MTI miRTarbase 1.25E-05 7.00E-02 1.53E-05 1.41E-04 19 122 "ANK1,CLCN3,RIMS4,HDAC4,MATR3,MYEF2,ABI2,BSCL2,COQ7,ZBED3,STAMBP,FYB1,GPD2,NUDT21,DDX19B,FNDC3A,FGD4,TAC1,WBP2" MicroRNA hsa-miR-4742-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-05 7.01E-02 1.53E-05 1.41E-04 16 91 "NCAN,EIF4G2,IGSF6,TMEM132C,FDFT1,C15orf41,HMGB1,ZIC5,RBPJ,GPR137C,PSAT1,SETD5,RMI1,TRPS1,TSN,RPL7L1" MicroRNA hsa-miR-4774-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-05 7.29E-02 1.59E-05 1.46E-04 12 54 "PNKD,CYBB,ABI2,GOLGA7,SOWAHA,POU3F2,RAB5B,PEX26,LRRC55,FGD4,FAM124A,VLDLR" MicroRNA hsa-miR-570-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-05 7.35E-02 1.60E-05 1.48E-04 14 72 "CALM1,CLCN3,MRO,PLEKHA1,PCDH17,PRUNE2,ELOVL5,PCDH9,PCMT1,PEX2,FBXW7,MCMBP,ZNF138,SLC38A1" MicroRNA hsa-miR-5002-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-05 7.35E-02 1.60E-05 1.48E-04 14 72 "HECTD1,ZFP28,SUCO,TNRC6A,PRRC2B,GRIK2,NEGR1,SCIN,GPR155,MKLN1,MAPK10,NXT2,PCDHA6,SMARCAD1" MicroRNA hsa-miR-7843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.31E-05 7.35E-02 1.60E-05 1.48E-04 14 72 "SFMBT2,FOXK1,DGKI,COL9A2,TOM1,ZNF391,ATP13A4,PCDH9,PDE3A,KLHL11,ANKRD24,TPM3,ZNF225,STOX2" MicroRNA hsa-miR-6776-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-05 7.58E-02 1.65E-05 1.52E-04 13 63 "ADARB2,SLC24A4,QKI,KIAA0040,ANKRD46,HIPK3,TMTC1,SRCAP,SHISAL1,METTL21A,KCNB1,GPR155,SLC1A2" MicroRNA hsa-miR-758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-05 7.58E-02 1.65E-05 1.52E-04 13 63 "TMEM263,USP6NL,E2F5,DCTN4,STAMBP,SESN3,ZDHHC22,OLA1,ZNF655,SETD5,ZNF415,SON,ZNF195" MicroRNA hsa-miR-3117-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.39E-05 7.80E-02 1.70E-05 1.57E-04 10 38 "SPOP,ABCD2,CREM,LONRF1,SMAD1,RAB5B,TCF7L2,TRIM2,UBTF,UGT8" MicroRNA hsa-miR-4747-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-05 7.91E-02 1.72E-05 1.59E-04 11 46 "GPRIN1,ATM,RGS6,WASF3,ZBTB45,IBA57,XRN1,FAT3,RAB5B,RBBP6,PTGR2" MicroRNA hsa-miR-219a-5p:Functional MTI Functional MTI miRTarbase 1.41E-05 7.91E-02 1.72E-05 1.59E-04 11 46 "CAMK2G,PUM1,EGFR,RAB30,RASSF8,MBNL1,MDM4,PCMT1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-4769-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-05 7.93E-02 1.73E-05 1.59E-04 15 82 "SLC7A14,ARSE,REPS2,QKI,BOC,EDN1,EDN3,EPB41,CELF1,RAPGEF1,ZNF546,PLCL1,RXRA,TMEM136,ZNF106" MicroRNA hsa-miR-323a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-05 7.93E-02 1.73E-05 1.59E-04 15 82 "ALCAM,ATP1B3,NDST3,ENTPD4,SIRPA,MTSS1L,ANKFY1,PLEC,MTRF1L,SKOR1,RBBP6,PRRT2,EMC1,PEG10,CRB1" MicroRNA hsa-miR-20a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-05 8.09E-02 1.76E-05 1.62E-04 16 92 "USP28,ZNF583,BID,CDC42,DLGAP2,RTTN,HINFP,CSNK1G3,YTHDC1,NCKAP1,NF1,PKIA,RPL15,STX1B,UGT8,FXR1" MicroRNA hsa-miR-4330:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-05 8.09E-02 1.76E-05 1.62E-04 16 92 "ESYT2,INTS2,C1QTNF3,BCAS1,MATR3,CAMKK2,SESN1,IL6R,MBNL1,TBL1X,TPM3,RPL7L1,ZNF24,ZXDA,MVB12B,RTN4" MicroRNA hsa-miR-6800-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-05 8.67E-02 1.89E-05 1.74E-04 14 73 "SORCS2,ENTPD4,CSNK1G3,KIAA0408,CHRDL1,PDLIM5,FAXC,NR3C1,RAB5B,TRIM67,MAPKBP1,TMPRSS5,MVB12B,SPATA13" MicroRNA hsa-miR-1247:mirSVR_highEffct hsa-miR-1247:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.54E-05 8.67E-02 1.89E-05 1.74E-04 14 73 "ADAM15,CS,WDR83,CLASRP,IRAK3,HP,HPR,MDM4,NPTX2,PEX5,SEMA6D,SLC1A7,SOX15,MYCBP2" MicroRNA hsa-miR-3167:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.54E-05 8.67E-02 1.89E-05 1.74E-04 14 73 "TAOK1,ABCG2,PYGO1,TOMM20,EPB41L1,SRRM4,CBX1,MAOB,MAT2A,P2RX7,P2RY1,ATXN1,ALG1,TPM4" MicroRNA hsa-miR-451a:Functional MTI Functional MTI miRTarbase 1.57E-05 8.81E-02 1.92E-05 1.76E-04 9 31 "CAB39,IL6R,OXTR,ABCB1,PKD1,ZDHHC14,CUX2,TSC1,UBE2H" MicroRNA hsa-miR-8056:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-05 8.81E-02 1.92E-05 1.76E-04 9 31 "CA8,CD86,NRXN1,ST18,TOMM20,PPM1L,ATXN1,HEY2,TPM4" MicroRNA hsa-miR-5094:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.89E-02 1.93E-05 1.78E-04 12 55 "ABCD2,MATR3,NEURL4,TNRC6A,LYPLAL1,PLCL1,SLC22A23,ERI2,SLC25A36,PCMTD2,KIAA0895L,EVI5" MicroRNA hsa-miR-767-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.89E-02 1.93E-05 1.78E-04 12 55 "CACNA1A,FBXL5,RCAN1,HIPK3,GSN,PPM1L,MMP16,CCDC80,UEVLD,GPRIN3,VLDLR,NUP214" MicroRNA hsa-miR-7112-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.58E-05 8.89E-02 1.93E-05 1.78E-04 12 55 "ELFN2,EVI5L,PUM1,CPLX1,TPPP,C2orf72,MDM4,MN1,NUMA1,ZNF713,SP2,BCL2L13" MicroRNA hsa-miR-3196:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.61E-05 9.06E-02 1.97E-05 1.81E-04 17 103 "DPF1,AMH,FOXK1,CBARP,ZNF385A,SLITRK5,SPATA2,KCNK3,MSI1,NEUROD2,NRGN,OLR1,FXYD1,SBF1,MAPK8IP3,WSCD1,TPM3" MicroRNA hsa-miR-499a-5p:Functional MTI Functional MTI miRTarbase 1.62E-05 9.07E-02 1.97E-05 1.81E-04 13 64 "AXIN2,LIN54,DGKG,CELF1,IQGAP2,KPNA5,ARHGAP12,MAPK10,ZNF844,SOX6,ASAP3,FGD4,TMEM178B" MicroRNA hsa-miR-3936:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-05 9.07E-02 1.97E-05 1.81E-04 13 64 "NIPBL,IP6K1,POLL,CECR2,FRMD5,ZNF678,MAT2A,SH3TC2,TMCC1,ZCCHC24,AP4E1,KLC2,GAN" MicroRNA hsa-miR-3127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-05 9.07E-02 1.97E-05 1.81E-04 13 64 "PRX,SEC16A,ABI2,DMTN,ERBB2,TNRC6A,RAPGEF1,KPNA5,SLC22A23,MYH14,RMI1,GALNT10,SLC30A3" MicroRNA hsa-miR-1292:PITA hsa-miR-1292:PITA_TOP PITA 1.64E-05 9.19E-02 2.00E-05 1.84E-04 7 18 "STX16,CAMK2B,IP6K1,SLC12A6,NCAM1,CPEB3,SLC11A1" MicroRNA hsa-miR-187-3p:TargetScan hsa-miR-187-3p TargetScan 1.64E-05 9.19E-02 2.00E-05 1.84E-04 7 18 "ACHE,LRFN1,NIPBL,NRG2,CRMP1,HIPK3,GTDC1" MicroRNA hsa-miR-4437:Functional MTI Functional MTI miRTarbase 1.64E-05 9.23E-02 2.00E-05 1.84E-04 15 83 "CPNE5,ARHGDIA,RIPOR2,PLEKHM1,RUSC2,AMOTL2,NEGR1,ITPKB,HKR1,SETD5,DRAXIN,SLC6A8,BDP1,CLUAP1,SF1" MicroRNA hsa-miR-3130-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-05 9.23E-02 2.00E-05 1.84E-04 15 83 "WDR35,AK2,DST,BTF3L4,CRY2,SV2B,FUT9,FAXC,NR3C1,DDX19B,ZNF491,GPR137C,SLITRK3,ZHX3,LHPP" MicroRNA hsa-miR-4482-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-05 9.32E-02 2.02E-05 1.86E-04 16 93 "KIAA0319,DDX46,KLHL5,RCAN2,GABRB1,TNRC6A,IBA57,MBNL1,CCSER2,TRAPPC13,SALL1,MYO18A,KIF13A,CAMSAP2,KIAA0930,TRPC3" MicroRNA hsa-miR-516b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-05 9.32E-02 2.02E-05 1.86E-04 16 93 "ABAT,ASTN1,LURAP1,LRRFIP1,TM9SF4,FKTN,LILRA2,RFFL,SHISAL1,NCOA7,GDAP1L1,PSAT1,HSPA4L,SMARCE1,ZFP91,GORASP1" MicroRNA hsa-miR-3682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.86E-02 2.14E-05 1.97E-04 11 47 "ARSE,CACNG7,SMC2,DOCK7,KCNK2,ZNF680,CNNM2,WLS,TMEM200C,KIF21A,TCEA1" MicroRNA hsa-miR-4638-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.86E-02 2.14E-05 1.97E-04 11 47 "APBB2,CDC14B,DPY19L3,MYRF,TMEM184B,IGDCC3,STX1B,C11orf87,CRTC1,TGFBR3,CELF4" MicroRNA hsa-miR-4460:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.76E-05 9.86E-02 2.14E-05 1.97E-04 11 47 "DST,SIRPA,ZC3H11A,GATM,RAB30,HMGB1,SMOX,CNKSR2,ZNF621,DDHD2,ZXDA" MicroRNA hsa-miR-512-5p:Functional MTI Functional MTI miRTarbase 1.78E-05 1.00E-01 2.17E-05 2.00E-04 20 136 "ELFN2,OGT,CDC14B,ZNF583,BCL2L2,CBFA2T2,GPR37L1,NRXN3,ELMSAN1,CEND1,ZNF585B,DOT1L,GPR75,IBA57,KCNJ5,MAT2A,VWA2,NUCB1,MTMR10,SLC2A5" MicroRNA hsa-miR-7150:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.78E-05 1.00E-01 2.17E-05 2.00E-04 20 136 "LONRF2,ZMYM4,PITPNM3,PHF19,KIAA0513,TOMM20,CD99L2,TUBD1,APOPT1,GABRB1,MALT1,TNRC6A,FUT10,DDX19B,NFIX,PDE3A,AMER2,MYH15,SATB2,DPYSL5" MicroRNA hsa-miR-4461:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-05 1.02E-01 2.21E-05 2.03E-04 14 74 "SEMA7A,APP,NCOA1,CLOCK,GUCD1,GOLT1B,MRO,ZNF589,ZNF678,CHIC1,ZNF426,RPRD1A,ZFP91,VSNL1" MicroRNA hsa-miR-518c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-05 1.02E-01 2.21E-05 2.03E-04 14 74 "CLU,TMEM184B,IGDCC3,SEZ6,KLHL23,PDE3A,PDE1B,SEPT4,NCBP3,R3HDM2,ZNF621,FBXL16,SSBP2,CLDND1" MicroRNA hsa-miR-6812-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-05 1.02E-01 2.21E-05 2.03E-04 14 74 "ABCF1,AKAP5,CRY2,RNF14,GNE,FECH,TRAF3IP2,GPR75,KIAA1958,LINC01551,MTMR10,GPR161,ZNF34,ZNF74" MicroRNA hsa-miR-3191-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-05 1.07E-01 2.32E-05 2.13E-04 16 94 "RNF157,CLU,RASSF2,C2CD2L,EDN3,SEZ6,TLX1,SYTL4,P2RX7,PDE3A,PDE1B,PDPK1,ZFP1,ZNF415,FBXL16,SSBP2" MicroRNA hsa-miR-4266:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-05 1.07E-01 2.32E-05 2.13E-04 16 94 "MTUS1,TOGARAM2,TNK2,KATNAL1,CHIC1,ZC3H12B,NELL2,OLR1,PDE4D,FTO,POLR2F,ALG9,SLIT1,UNC5B,FAM168A,FGD4" MicroRNA hsa-miR-4511:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.91E-05 1.07E-01 2.32E-05 2.13E-04 15 84 "TMCC3,TAOK1,MIER1,ISPD,KIAA0513,ABCC9,RTN3,GFER,GJB1,GLUL,GRIK4,HAS2,LAMA2,AFF1,BDP1" MicroRNA hsa-miR-5581-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-05 1.08E-01 2.33E-05 2.15E-04 12 56 "SEPT7,SIPA1L1,DNAJB6,GRIK3,HAS2,NKD1,ADAM22,TNPO2,ZDHHC14,MSANTD2,NSD1,WIPF2" MicroRNA hsa-miR-146b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-05 1.08E-01 2.33E-05 2.15E-04 12 56 "CPS1,FAM107A,MAT2A,CAMKV,ATXN1,TRIM67,CPEB4,GANAB,SZT2,TPM3,GDPD5,XKR7" MicroRNA hsa-miR-365b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.99E-05 1.12E-01 2.42E-05 2.23E-04 19 126 "ESYT2,ATP1B3,ZMYM4,RNF14,HINFP,DNAL1,TUBD1,SLC43A2,FKTN,RAPGEF1,GRIK3,KCNK3,NUCB1,IGSF9B,ARHGAP26,ATP11A,TPM3,LAT2,CFAP298" MicroRNA hsa-miR-574-3p:PITA hsa-miR-574-3p:PITA_TOP PITA 2.08E-05 1.17E-01 2.53E-05 2.33E-04 9 32 "ATP2A2,DCAF5,NIPA1,CLTC,FBXL5,FHL1,STRN3,RXRA,WASHC4" MicroRNA hsa-miR-181c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.08E-05 1.17E-01 2.53E-05 2.33E-04 9 32 "G3BP2,HIPK3,TMEM175,TBR1,ADAMTS13,KCNN3,GPR137C,RAB5B,TPM3" MicroRNA hsa-miR-4536-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-05 1.18E-01 2.55E-05 2.35E-04 6 13 "ISPD,DBN1,PFKP,STX1B,NACC2,USP1" MicroRNA hsa-miR-5007-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 14 75 "WDR35,ATM,ANKRD46,WAC,FRMD3,OPHN1,SALL1,AJAP1,KLHL4,BHLHB9,UBE3A,VLDLR,ZNF711,WNK1" MicroRNA hsa-miR-452-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 14 75 "BEND6,HACE1,TXNDC16,BAG4,DPYSL2,HEYL,DOT1L,GFRA1,SEMA6D,TMCC1,ZNF621,TCF4,CLASP1,WNK1" MicroRNA hsa-miR-29b-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 14 75 "PNKD,AKAP12,PLEKHM1,ATP8A2,GPR155,MAT2A,KITLG,MMP16,NEUROD1,EPB41L4B,RUFY2,ZNF430,SNAP25,STMN4" MicroRNA hsa-miR-3178:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 14 75 "SLC12A5,PTCHD1,TRMT9B,AMH,AQP6,NCOR2,CPLX1,BVES,IRAK3,MDM4,FXYD1,ZNF426,ELP2,ZKSCAN3" MicroRNA hsa-miR-7844-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 14 75 "OSBPL1A,EIF5,SEMA4D,SLC35G1,MEF2C,OPHN1,GPR137C,PDZRN4,PTPRG,PBRM1,CSRNP3,SOX11,ASXL3,ZIC2" MicroRNA hsa-miR-524-5p:Functional MTI Functional MTI miRTarbase 2.13E-05 1.20E-01 2.58E-05 2.38E-04 23 172 "MTA3,ST3GAL5,COPB2,GUCD1,SV2B,EDN1,STARD3NL,CACNG2,TACC2,GABRB3,RNPS1,NR3C1,ZIC5,PFKP,PDZRN4,PSD,RNASEL,ROBO1,ZNF415,FAM126B,NXT2,TMEM178B,SMARCAD1" MicroRNA hsa-miR-4687-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-05 1.22E-01 2.63E-05 2.42E-04 11 48 "FOXK1,CACNA1A,C1orf52,NDST3,AKAP6,B4GALNT4,ADAP1,ZNF793,KCNIP3,UNC80,FNBP1" MicroRNA hsa-miR-2681-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.17E-05 1.22E-01 2.63E-05 2.42E-04 11 48 "TBPL1,SYNCRIP,SMC2,ZNF678,OLA1,OCIAD1,GTDC1,PGBD4,DRAXIN,BDP1,ZNF28" MicroRNA hsa-miR-516a-3p:Functional MTI Functional MTI miRTarbase 2.19E-05 1.23E-01 2.65E-05 2.44E-04 16 95 "ABAT,ASTN1,LURAP1,LRRFIP1,TM9SF4,FKTN,LILRA2,RFFL,SHISAL1,NCOA7,GDAP1L1,PSAT1,HSPA4L,SMARCE1,ZFP91,GORASP1" MicroRNA hsa-miR-16-2-3p:Functional MTI Functional MTI miRTarbase 2.21E-05 1.24E-01 2.67E-05 2.46E-04 15 85 "BID,CBS,CCNT1,CLCN3,ABCG2,ACBD5,PREPL,SH3GLB1,UBE2E3,RBBP6,ERBIN,TUBB2A,CCDC14,TBC1D15,VSNL1" MicroRNA hsa-miR-10b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.21E-05 1.24E-01 2.67E-05 2.46E-04 15 85 "SEMA4G,ZBTB10,MATR3,EIF5,ELAVL4,DNAJC27,SUCO,ZBTB49,NOVA2,PCSK1,SH3TC2,SALL1,SEMA6D,CLSTN2,FGD4" MicroRNA hsa-miR-4515:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-05 1.28E-01 2.75E-05 2.53E-04 10 40 "ESYT2,LDB2,E2F6,CAB39,WASF3,RNF165,NUCB1,OPHN1,KCTD15,TPM3" MicroRNA hsa-miR-5187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-05 1.29E-01 2.76E-05 2.55E-04 13 66 "BACH1,CDC25B,SEC24C,DCAF8,DNAL1,SPATA2,ING4,GLUL,PRRC2B,NCR3LG1,STX1B,SARS,ZFP91" MicroRNA hsa-miR-15b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-05 1.29E-01 2.76E-05 2.55E-04 13 66 "ABCD2,CACNA1B,BACH2,ZC3H12B,RETREG2,CNTLN,GTDC1,KIAA0895L,MCMBP,CSRNP3,ITPRID2,ZNF708,ZNF28" MicroRNA hsa-miR-4704-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-05 1.29E-01 2.76E-05 2.55E-04 13 66 "AK2,BAG4,TPK1,MDM4,DDR2,PKD1,GPSM2,PNMA3,PTPRE,NCBP3,USP22,DHX33,FXR1" MicroRNA hsa-miR-1208:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-05 1.29E-01 2.76E-05 2.55E-04 13 66 "TMEM132B,ABCD2,ZIC4,DOT1L,FYN,GABRB1,NUMA1,OPHN1,SALL1,HSPA4L,FAM126B,ZNF621,AMACR" MicroRNA hsa-miR-5088-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-05 1.29E-01 2.76E-05 2.55E-04 13 66 "MARCH4,CPNE5,ARHGDIA,CABP7,PLEKHM1,SEC16A,AMOTL2,SEMA4D,NEGR1,KPNA5,NLGN1,NFASC,MEAF6" MicroRNA hsa-miR-718:mirSVR_highEffct hsa-miR-718:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.32E-05 1.31E-01 2.81E-05 2.59E-04 12 57 "BCAS1,CALB2,CBLN1,PPT2,GDA,FRY,TMEM35A,NSG2,COPS8,AFDN,MAPK9,ITSN1" MicroRNA hsa-miR-2117:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.32E-05 1.31E-01 2.81E-05 2.59E-04 12 57 "FOXK1,BTF3L4,SH3GLB1,SEZ6,CACNG2,TUBGCP4,TNRC6A,PDE1B,PDPK1,ZNF793,DNAJC9,NAV2" MicroRNA hsa-miR-3155a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.47E-05 1.39E-01 2.99E-05 2.75E-04 18 117 "ABCF1,ATP1A2,BSN,PREPL,EXOG,TOMM40L,GPR26,GPR155,MAT2A,C12orf49,ELP2,NUBPL,ATF7IP,ANKRD36,CLUAP1,ZNF621,SGK3,PMEPA1" MicroRNA hsa-miR-3155b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.47E-05 1.39E-01 2.99E-05 2.75E-04 18 117 "ABCF1,ATP1A2,BSN,PREPL,EXOG,TOMM40L,GPR26,GPR155,MAT2A,C12orf49,ELP2,NUBPL,ATF7IP,ANKRD36,CLUAP1,ZNF621,SGK3,PMEPA1" MicroRNA hsa-miR-4648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-05 1.40E-01 3.01E-05 2.77E-04 14 76 "LONRF2,PPP1R16B,DCAF8,E2F6,ABI2,NEGR1,NRGN,NUCB1,PKM,PMP22,CAMTA2,TPM3,LAT2,WNK2" MicroRNA hsa-miR-8077:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.49E-05 1.40E-01 3.01E-05 2.77E-04 14 76 "TTYH1,KIF6,ADGRG1,KIAA0408,IST1,TOMM20,SV2B,FGFR1,PKM,EPB41L4B,QDPR,CHD9,IQSEC2,TUBB2A" MicroRNA hsa-miR-181c*:mirSVR_highEffct hsa-miR-181c*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.50E-05 1.40E-01 3.02E-05 2.78E-04 16 96 "DACT3,ATM,MTMR9,THSD7A,CFL2,LRRC3B,EMX2,PPARGC1A,PTPN5,LIG4,SMAD1,RTL5,SCN7A,PPP4R3A,OSBP2,RICTOR" MicroRNA hsa-miR-3921:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-05 1.43E-01 3.08E-05 2.83E-04 15 86 "PPP1R16B,ERBB2,TOMM40L,TACC2,TLX1,CLVS2,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ACSL6,ARL10,PRMT8,ZNF708" MicroRNA hsa-miR-3188:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-05 1.43E-01 3.08E-05 2.83E-04 15 86 "ABAT,SLC24A4,CEP126,ARHGDIA,MTMR3,CCNT1,CRY2,RIMS4,KIAA0408,SRCAP,SETD5,WDTC1,DDN,WNK1,URM1" MicroRNA hsa-miR-4320:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-05 1.50E-01 3.22E-05 2.97E-04 11 49 "TAOK1,NRXN1,CRY2,HLF,MPP2,UHRF1BP1L,ZNF621,TBX15,CLASP1,WIPF2,MPPE1" MicroRNA hsa-miR-6762-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-05 1.50E-01 3.22E-05 2.97E-04 11 49 "NCOA1,NIPBL,SV2B,MRVI1,SRRM4,GPT2,CREG2,MAP4,NFIX,SLC1A7,ZNF610" MicroRNA hsa-miR-3689f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-05 1.50E-01 3.22E-05 2.97E-04 11 49 "SDC3,ZBED3,CELF1,ZNF181,MDM4,CLIP1,CSRNP3,FAM126B,SMOC1,TPCN2,BCL2L13" MicroRNA hsa-miR-4693-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-05 1.50E-01 3.22E-05 2.97E-04 11 49 "SDE2,HEYL,AP4S1,RBPJ,LIMS1,MBNL1,MMP16,ALG9,ELP2,TMEM200C,CLASP1" MicroRNA hsa-miR-3177:mirSVR_highEffct hsa-miR-3177:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.69E-05 1.51E-01 3.24E-05 2.98E-04 17 107 "ATP1B3,LY86,VCAN,CFAP61,PRELID3A,TRAF3IP2,FAM120B,ZIC5,NELL1,PCDH9,FIGN,TTC17,MBD5,SYN1,PCDHA2,ZIC2,CAMK1G" MicroRNA hsa-miR-539-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-05 1.52E-01 3.26E-05 3.00E-04 13 67 "ARID1A,DST,CANX,CLTC,RCAN2,TESK2,SRCAP,MKLN1,KANSL1,SS18,TCF7L2,INTS3,ACTR3B" MicroRNA hsa-miR-134-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-05 1.52E-01 3.26E-05 3.00E-04 13 67 "TRMT9B,FOXK1,LONRF2,PYGO1,ABI2,POLL,NOVA2,PPP2R5C,SHMT2,PEX26,ARC,WNK1,WNK2" MicroRNA hsa-miR-6755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.74E-05 1.54E-01 3.30E-05 3.04E-04 9 33 "SOCS6,WDPCP,HSP90AA1,RDX,SLC22A4,KIF1B,POGZ,WNK1,PMEPA1" MicroRNA hsa-miR-7702:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.74E-05 1.54E-01 3.30E-05 3.04E-04 9 33 "ELMSAN1,EFNA3,PTPRT,RXRA,FOXRED2,ELOVL4,STXBP4,ZBTB38,FXR1" MicroRNA hsa-miR-8058:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.74E-05 1.54E-01 3.30E-05 3.04E-04 9 33 "LRWD1,E2F6,HIPK3,EN2,RNF165,OPHN1,FITM2,MYO18A,SLC30A4" MicroRNA hsa-miR-577:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.79E-05 1.57E-01 3.36E-05 3.10E-04 19 129 "SEMA7A,CNN3,AKAP12,ATRNL1,SMG7,WAC,MMADHC,TNRC6A,NUDT21,IGSF1,ZFYVE21,KCTD15,PXK,SH3TC2,SLC25A36,PGBD4,TAL1,SF1,EVI5" MicroRNA hsa-miR-4536-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.36E-05 3.10E-04 12 58 "FMNL2,OSBPL8,UBXN2A,SIRPA,ZC3H11A,TENM1,DDX19B,MTRF1L,RAB5B,ATXN1,PRRC2C,ITGB3BP" MicroRNA hsa-miR-4454:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.80E-05 1.57E-01 3.36E-05 3.10E-04 12 58 "ATM,MTMR9,ENTPD4,MYADM,GNE,CRCP,ATCAY,KCNN1,PIK3C2A,GDPD1,UGT8,MEAF6" MicroRNA hsa-miR-4782-3p:Functional MTI Functional MTI miRTarbase 2.87E-05 1.61E-01 3.45E-05 3.18E-04 10 41 "PUM1,ZEB2,RAB30,RASSF8,MBNL1,MDM4,PCMT1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-509-3p:Functional MTI Functional MTI miRTarbase 2.87E-05 1.61E-01 3.45E-05 3.18E-04 10 41 "ARHGEF7,SDC3,NR1D2,NTRK3,FITM2,UHRF1BP1,RAD51D,RGR,CBX5,TNR" MicroRNA hsa-miR-4704-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.87E-05 1.61E-01 3.45E-05 3.18E-04 10 41 "FMNL2,CAMK2G,PUM1,MAGI2,EIF1,ADAM22,SOX5,PEG10,CSMD1,MKRN3" MicroRNA hsa-miR-5572:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-05 1.63E-01 3.49E-05 3.21E-04 14 77 "CACNB2,MICAL2,PDLIM5,HBS1L,GLI2,TNRC6A,PRRC2B,SCIN,MDM4,MSI1,MAPK10,DRAXIN,NMNAT2,MEAF6" MicroRNA hsa-miR-4260:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-05 1.63E-01 3.49E-05 3.21E-04 14 77 "CACNB2,DNAJC6,HBS1L,GLI2,TNRC6A,PRRC2B,ELOVL5,SCIN,MDM4,MSI1,MAPK10,DRAXIN,NMNAT2,MEAF6" MicroRNA hsa-miR-874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-05 1.63E-01 3.49E-05 3.21E-04 14 77 "ATP2A2,RGS6,CRCP,FAM107A,GPR45,HPR,MAPT,CAMKV,OCIAD1,ATXN1,TRIM67,CPEB4,GDPD5,XKR7" MicroRNA hsa-miR-6078:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-05 1.64E-01 3.52E-05 3.24E-04 8 26 "FOXK1,ZNF638,LUZP2,ATOH8,METTL21A,CYP27C1,MDM4,TMEM198" MicroRNA hsa-miR-375:PITA hsa-miR-375:PITA_TOP PITA 2.93E-05 1.64E-01 3.52E-05 3.24E-04 8 26 "PLEKHH1,DPYSL2,ELAVL4,SYNCRIP,ATF7,NFIX,WBP1L,ROBO2" MicroRNA hsa-miR-4653-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-05 1.65E-01 3.53E-05 3.25E-04 15 87 "PPP1R16B,ERBB2,TOMM40L,TACC2,TLX1,CLVS2,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,ACSL6,ARL10,PRMT8,ZNF708" MicroRNA hsa-miR-365b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.94E-05 1.65E-01 3.53E-05 3.25E-04 15 87 "ADCYAP1R1,PCDH10,SLC7A14,BTF3L4,AKAP12,CS,ABI2,POLR1B,COMMD5,KANSL1,SNRK,CYB561D1,PCMTD2,SGK1,ZXDA" MicroRNA hsa-miR-214-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-05 1.74E-01 3.72E-05 3.42E-04 24 188 "ADCY5,PLEKHH1,STX16,SYNJ2,CBS,ZFYVE9,AKAP5,GREB1,DNAL1,YTHDC1,TOM1,TRAF3IP2,GBX2,IGF1,KCNJ5,PEX2,NCBP3,SMARCC2,INAVA,UNC5B,RPL7L1,ZNF17,ZNF154,FBXO36" MicroRNA hsa-miR-6732-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-05 1.75E-01 3.74E-05 3.44E-04 19 130 "PLEKHG5,CBS,USP6NL,TMEM170A,NSG2,LILRA2,MAT2A,KSR2,NCBP3,FOXRED2,TRA2B,URGCP,SON,FAM208A,AHCYL2,HHIP,CADM1,ZNF708,HPS4" MicroRNA hsa-miR-4309:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.12E-05 1.75E-01 3.75E-05 3.45E-04 18 119 "SEMA7A,DNAL1,DNAJB6,CAMKK2,GLUL,ZNF426,PXK,ELP2,ATXN1,SCN2B,ELMOD1,HSPA4L,NUBPL,FAM126B,CDK19,KIAA0930,ZNF384,ZNF708" MicroRNA hsa-miR-1181:PITA hsa-miR-1181:PITA_TOP PITA 3.14E-05 1.76E-01 3.77E-05 3.47E-04 4 5 "PPFIA3,NRXN2,CTIF,NEUROD2" MicroRNA hsa-miR-128-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.19E-05 1.79E-01 3.83E-05 3.53E-04 13 68 "PLEKHG5,GRAMD1B,TOM1,DOT1L,NKX6-2,SEPT9,NEUROD2,NFIX,NKX2-2,LIMS2,MPRIP,STX1A,DNMBP" MicroRNA hsa-miR-921:Functional MTI Functional MTI miRTarbase 3.19E-05 1.79E-01 3.83E-05 3.53E-04 13 68 "ASPH,CBR1,FOXN3,BAG4,MTX3,OCRL,ZFYVE21,KANSL1,RDX,ROBO1,TRA2B,SLC6A8,RBFOX2" MicroRNA hsa-miR-6824-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-05 1.84E-01 3.92E-05 3.61E-04 11 50 "ELFN2,MTA3,METTL6,TMCC2,KCND1,OGG1,PKD1,TNPO2,HKR1,SETD5,ZNF423" MicroRNA hsa-miR-549a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-05 1.84E-01 3.92E-05 3.61E-04 11 50 "TAOK1,COPB2,IQGAP2,GLUL,KIT,ATXN1,NBPF1,MPRIP,TPCN2,RPL7L1,ZNF708" MicroRNA hsa-miR-6841-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.27E-05 1.84E-01 3.92E-05 3.61E-04 11 50 "TNRC6C,CALM1,TPP1,TOMM20,ABI2,TNFAIP8L3,SHISA6,MEIS1,OCIAD1,TRIM67,SS18" MicroRNA hsa-miR-454-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-05 1.88E-01 4.01E-05 3.69E-04 12 59 "AK2,ASGR1,LDHD,RCAN1,PLEKHA1,NUDT21,HSF2,KCNJ10,DDR2,ATXN1,TMPO,AP3B2" MicroRNA hsa-miR-649:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.35E-05 1.88E-01 4.01E-05 3.69E-04 12 59 "SLC2A11,CCNT1,YTHDC1,YAF2,LILRA2,HNRNPK,ZIC5,MYO5A,SLC2A5,SOX1,PUM2,ARL10" MicroRNA hsa-miR-4654:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.37E-05 1.90E-01 4.04E-05 3.72E-04 14 78 "LONRF2,NRG2,SEC24C,DCAF8,E2F6,ABI2,GLUL,NEGR1,METTL21A,NRGN,PMP22,CAMTA2,CLASP1,WNK2" MicroRNA "CGCAAAA,MIR-450:MSigDB" "CGCAAAA,MIR-450:MSigDB" MSigDB 3.51E-05 1.97E-01 4.20E-05 3.87E-04 5 9 "NRXN2,ZNF385A,DSCAM,MEIS2,SOX2" MicroRNA hsa-miR-6069:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.59E-05 2.02E-01 4.30E-05 3.96E-04 10 42 "LDHD,COL9A2,CRY2,EBI3,FGF1,FOXO3,TMEM151A,FAM107A,MRAS,INTS3" MicroRNA hsa-miR-4462:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-05 2.05E-01 4.36E-05 4.02E-04 7 20 "PPFIA3,BAIAP3,OCRL,PKD1,LIMCH1,ERC1,MPRIP" MicroRNA hsa-miR-1180:PITA hsa-miR-1180:PITA_TOP PITA 3.65E-05 2.05E-01 4.36E-05 4.02E-04 7 20 "IGDCC3,HPCAL4,TNPO2,PPP2R5E,KANSL1,CEP41,HECW1" MicroRNA hsa-miR-6840-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.65E-05 2.05E-01 4.36E-05 4.02E-04 7 20 "GPRIN1,ANK1,CACNA1E,IL1RAPL1,PFKFB3,MGRN1,ICAM5" MicroRNA hsa-miR-3611:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-05 2.08E-01 4.42E-05 4.07E-04 16 99 "CDC14B,CA8,SPAG9,CCNT1,CNGA3,COL9A2,NR1D2,GOLT1B,MRO,CELF1,PDE4D,SLC25A23,PPP2R5C,ALG9,SALL1,STOX2" MicroRNA hsa-miR-455-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-05 2.08E-01 4.42E-05 4.07E-04 16 99 "RUNX1T1,QKI,RASSF2,TMEM170A,DYRK1A,CAMSAP1,PIK3R1,PTPRB,ZNF354C,SEPHS1,IGSF9B,SOX11,ARC,MGRN1,ZNF138,ZFAND5" MicroRNA hsa-miR-3974:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-05 2.11E-01 4.48E-05 4.13E-04 13 69 "ABCF1,TXNDC16,BTRC,SRSF11,CRY2,PHF19,TUBB4A,CRCP,NXPH3,MAP2,ZNF713,KANSL1,HUNK" MicroRNA hsa-miR-6774-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-05 2.11E-01 4.48E-05 4.13E-04 13 69 "SEMA7A,ARHGDIA,CACNA2D2,SUMF2,ELAVL3,EPB41,CELF1,CRCP,CNNM2,DRAXIN,SLC30A10,ZKSCAN3,LINC00632" MicroRNA hsa-miR-7106-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-05 2.11E-01 4.48E-05 4.13E-04 13 69 "TAOK1,C6orf89,CACNA1A,AKAP5,ZNF385A,HIPK3,KSR2,BEST3,FIGN,KANSL3,ARC,NACC2,TMEFF2" MicroRNA hsa-miR-1233-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-05 2.17E-01 4.62E-05 4.25E-04 19 132 "KIF6,GPR37L1,EPS15L1,RGS6,TOMM20,E2F5,ZNF585B,GPR75,MUM1,KCNH1,KCNJ11,FTO,MSANTD2,CSRNP3,SCN4B,ZCCHC24,TAL1,AHCYL2,TMEM63C" MicroRNA hsa-miR-500a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-05 2.17E-01 4.62E-05 4.25E-04 19 132 "DST,FADS2,HP1BP3,ELAVL2,FYN,SIGLEC8,MTHFD2,KIAA1958,PRRC2B,LILRA2,AGBL5,IBA57,PIK3CD,STRN3,NWD1,KLHL11,LRRC55,ZBTB43,MCF2L2" MicroRNA hsa-miR-151a-5p:Functional MTI Functional MTI miRTarbase 3.91E-05 2.20E-01 4.67E-05 4.30E-04 14 79 "ARHGDIA,BCL7A,CRMP1,PLEKHM1,E2F6,EIF4G2,ZNF512,GPER1,IL1RAPL1,OGDH,RFX2,SLC6A1,CAMTA2,SPIRE1" MicroRNA hsa-miR-6888-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.91E-05 2.20E-01 4.67E-05 4.30E-04 21 155 "SMIM17,PDZD4,TTLL9,TOGARAM2,NOS1AP,GAPVD1,WAC,MDFI,PDE4D,CEP97,SH3TC2,HSD11B1L,HES6,SLC8A1,MYH15,MCF2L2,FAM168A,TMEM136,SLC19A3,BHLHB9,SSBP2" MicroRNA hsa-miR-3198:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.92E-05 2.20E-01 4.68E-05 4.31E-04 18 121 "SEMA7A,DNAL1,DNAJB6,CAMKK2,GLUL,ZNF426,PXK,ELP2,ATXN1,SCN2B,ELMOD1,HSPA4L,NUBPL,FAM126B,CDK19,KIAA0930,ZNF384,ZNF708" MicroRNA hsa-miR-145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-05 2.24E-01 4.76E-05 4.39E-04 12 60 "CADM3,TMCC2,C8orf37,POLL,GUCY1A2,MMP16,NTRK2,ACER3,TRA2B,CLSTN2,TPM1,JMJD1C" MicroRNA hsa-miR-6722-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-05 2.24E-01 4.76E-05 4.39E-04 12 60 "ABCF1,MTA3,TTLL9,SYNJ2,MSANTD4,KDM2B,GRID1,APTX,FAM102A,ATF7IP,MAP3K12,RNF170" MicroRNA hsa-miR-6807-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.99E-05 2.24E-01 4.76E-05 4.39E-04 12 60 "INSYN2B,ZNF583,SRSF11,HINFP,OSBPL3,DNAL1,MTX3,TCERG1,BACH2,HSPA4L,TCF7L2,FXR1" MicroRNA hsa-miR-4714-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.40E-05 2.47E-01 5.24E-05 4.83E-04 13 70 "ADCY2,IGDCC3,TUBD1,TACC2,ZNF678,KLHL23,MOG,CAMKV,BCAS3,ZYG11B,NCBP3,DIP2A,ACSL6" MicroRNA hsa-miR-4748:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-05 2.49E-01 5.28E-05 4.87E-04 15 90 "MTUS1,KIF6,CHD5,ENPP6,ERBB2,HBS1L,GLI2,SLC2A6,ELOVL5,GLIPR1L2,CNNM2,MARCH1,SEPHS1,TNS1,WRN" MicroRNA hsa-miR-5700:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-05 2.49E-01 5.28E-05 4.87E-04 15 90 "FZD9,TNRC6C,KIAA1549L,PHF19,ZBED3,KIAA1841,ZIC5,ZNF678,PURG,TROVE2,FNDC9,TMEM136,TJP1,TNS1,ZNF711" MicroRNA hsa-miR-7155-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-05 2.49E-01 5.28E-05 4.87E-04 15 90 "ADD1,BMP7,CRLF1,DIS3L,ZNF385A,SOCS5,IP6K1,PLEKHM1,RASA4,TUBB4A,ZNF491,SPATA6,KLHDC8A,CLSTN1,UNC5B" MicroRNA hsa-miR-376c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-05 2.51E-01 5.32E-05 4.90E-04 10 43 "CA8,CD86,NRXN1,ST18,MKLN1,CEP97,PCDHA6,FRYL,HEY2,TPM4" MicroRNA hsa-miR-376b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-05 2.51E-01 5.32E-05 4.90E-04 10 43 "CA8,CD86,NRXN1,ST18,MKLN1,CEP97,PCDHA6,FRYL,HEY2,TPM4" MicroRNA hsa-miR-3649:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-05 2.51E-01 5.32E-05 4.90E-04 10 43 "FMNL3,ENTPD4,MRPL10,PCYOX1,ANKFY1,HMX1,MTMR10,MYO18A,CYB561A3,XKR7" MicroRNA "TCTAGAG,MIR-517:MSigDB" "TCTAGAG,MIR-517:MSigDB" MSigDB 4.47E-05 2.51E-01 5.32E-05 4.90E-04 10 43 "BCL2L2,MAGED1,CS,FEZ2,MSTN,BRINP3,KCND2,ING3,TNPO2,SNAP25" MicroRNA hsa-miR-4660:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.54E-01 5.38E-05 4.95E-04 14 80 "PHF19,MAGI2,FAM13A,GLUL,KIAA1958,MBNL1,NBL1,RETREG2,ACER3,SLC1A7,TRIM67,WBP2,RUNDC3B,ACTR3B" MicroRNA hsa-miR-6504-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.54E-01 5.38E-05 4.95E-04 14 80 "ARHGDIA,NEURL1,SRRM4,IBA57,NFIX,PDE1B,NWD1,SLC1A7,SEPHS1,FNBP1,MAPK8IP3,FBXL16,ZNF610,ZNF24" MicroRNA hsa-miR-151a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.52E-05 2.54E-01 5.38E-05 4.95E-04 14 80 "PUM1,ZBTB24,EFNA3,CECR2,GRM3,NTRK3,SEPT8,AZIN2,CABIN1,STXBP4,ZNF711,ZBTB38,WNK3,FXR1" MicroRNA hsa-miR-4769-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.52E-05 2.54E-01 5.38E-05 4.95E-04 14 80 "LONRF2,NRG2,SEC24C,DCAF8,E2F6,ABI2,GLUL,NEGR1,METTL21A,NRGN,PMP22,CAMTA2,CLASP1,WNK2" MicroRNA hsa-miR-4256:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.57E-05 2.57E-01 5.44E-05 5.01E-04 9 35 "CCPG1,GPER1,NR3C1,KCNN1,SYTL4,LSAMP,KIF1B,CBX5,NSD2" MicroRNA hsa-miR-3681-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-05 2.66E-01 5.64E-05 5.19E-04 12 61 "FARSB,PNMA2,MALT1,NXPH3,PACSIN2,CEP97,ATXN1,ZNF621,TRIM2,PCDHA6,FRYL,ZXDA" MicroRNA hsa-miR-4501:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-05 2.66E-01 5.64E-05 5.19E-04 12 61 "FMNL2,INTS2,USP37,FOXK1,E2F6,EIF5,KATNAL1,IL6ST,PPM1L,PROX1,PEX26,SIN3B" MicroRNA hsa-miR-6815-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-05 2.66E-01 5.64E-05 5.19E-04 12 61 "CACNA1E,LURAP1,ZNF445,TM9SF4,LIN54,GRM5,RBPJ,NODAL,MTRF1L,SEPT4,TNPO2,ZNF331" MicroRNA hsa-miR-320e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-05 2.66E-01 5.64E-05 5.19E-04 12 61 "SEMA7A,CCNT1,TUBB4A,SRCAP,ZNF491,CCDC80,PABPC1L2A,SOX11,ARL10,MEAF6,ZNF70,ITM2C" MicroRNA hsa-miR-6849-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.74E-05 2.66E-01 5.64E-05 5.19E-04 12 61 "FARSB,PNMA2,MALT1,NXPH3,PACSIN2,CEP97,ATXN1,ZNF621,TRIM2,PCDHA6,FRYL,ZXDA" MicroRNA hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 4.75E-05 2.67E-01 5.65E-05 5.20E-04 16 101 "GALNT16,BRAP,DST,HDAC4,SIRPA,ZC3H11A,GALC,RAB30,MYO6,PAX6,PDGFRA,ZNF426,MEG3,CNKSR2,SOX2,FXR1" MicroRNA hsa-miR-519e-3p:Functional MTI Functional MTI miRTarbase 4.82E-05 2.71E-01 5.72E-05 5.27E-04 11 52 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,WAC,FLT1,AFF1,ADAM22,ZC3H12B,UEVLD" MicroRNA hsa-miR-3617-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.82E-05 2.71E-01 5.72E-05 5.27E-04 11 52 "SH3GLB1,FAM49B,NPTN,MTHFD2,SEMA6D,CPEB4,ANKRD28,KIAA0930,WRN,GDPD5,URM1" MicroRNA hsa-miR-889-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.82E-05 2.71E-01 5.72E-05 5.27E-04 11 52 "SLC25A25,ADAR,KIF6,NCOA1,NDST3,KIAA1958,MBNL1,PEX2,KCNIP3,UNC80,ARC" MicroRNA hsa-miR-185-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.90E-05 2.75E-01 5.81E-05 5.36E-04 17 112 "USP37,RGS6,ABCC5,ANKRD13B,PRRC2B,RAPGEF1,PKM,PTPA,RAB5B,KIAA0895L,SBF1,SCN2B,PEX26,THRA,WBP2,INTS3,TMEM63C" MicroRNA hsa-miR-452-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-05 2.84E-01 6.00E-05 5.53E-04 15 91 "CDC14B,PDE4DIP,SEC24B,SGIP1,GALR1,PCDH17,HMGB1,SH3TC2,ATXN7,LIMCH1,NSFL1C,FAM181B,ZBTB16,STMN4,ZDHHC20" MicroRNA hsa-miR-6833-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.06E-05 2.84E-01 6.00E-05 5.53E-04 15 91 "ADCY2,LDHD,SRSF11,KIAA0040,ZC3H11A,C8orf37,WAC,CRCP,GPT2,KCNJ10,PPP2R5C,MYO18A,ZNF106,HEY2,BCL2L13" MicroRNA hsa-miR-299-3p:Functional MTI Functional MTI miRTarbase 5.13E-05 2.88E-01 6.09E-05 5.61E-04 13 71 "DNAL1,E2F6,NEGR1,IGF1,MYCN,PMP22,ATXN2,SMTN,PEG10,ITGB3BP,TNFRSF1B,BCL2L13,NAV2" MicroRNA hsa-miR-369-5p:mirSVR_highEffct hsa-miR-369-5p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.21E-05 2.93E-01 6.18E-05 5.69E-04 14 81 "UPRT,OSGIN2,DIS3L,FAM171B,ABCG1,ARHGAP24,YTHDC1,DTNB,FAM198B,ATP2C1,FAAP20,WBP1L,ROBO3,FAM155A" MicroRNA hsa-miR-3064-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.21E-05 2.93E-01 6.18E-05 5.69E-04 14 81 "ARHGDIA,NEURL1,SRRM4,IBA57,NFIX,PDE1B,NWD1,SLC1A7,SEPHS1,FNBP1,MAPK8IP3,FBXL16,ZNF610,ZNF24" MicroRNA hsa-miR-345-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.21E-05 2.93E-01 6.18E-05 5.69E-04 14 81 "KIF6,ZNF385A,TOM1,WAC,TACC2,NEGR1,SLC35G1,LSAMP,PDPK1,HMGCLL1,UBR7,FNBP1,ZNF177,DHX33" MicroRNA hsa-miR-1247-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-05 2.94E-01 6.20E-05 5.71E-04 7 21 "CBARP,RIMS3,WAC,TESK2,HPR,ATXN1,KLC2" MicroRNA hsa-miR-4285:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-05 2.94E-01 6.20E-05 5.71E-04 7 21 "SLC12A5,FOXK1,BRSK2,ZNF385A,ECSIT,SLC6A1,SSTR1" MicroRNA hsa-miR-933:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.23E-05 2.94E-01 6.20E-05 5.71E-04 7 21 "APAF1,BCAS1,TBC1D16,UBE2E3,AFF2,KIF3A,SOX5" MicroRNA hsa-miR-4649-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-05 3.02E-01 6.37E-05 5.86E-04 16 102 "SLC16A4,CBARP,HP1BP3,ANKFY1,TRMO,FUT9,RNPS1,KCNN3,CHST6,PDE4A,ALG9,ATAT1,AP4E1,ARL10,PPIL6,UBC" MicroRNA hsa-miR-1255a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-05 3.02E-01 6.37E-05 5.86E-04 16 102 "TAOK1,GAS7,CPS1,ST18,SPATA2,C8orf37,RAPGEF1,KAT7,GPR137C,NCR3LG1,C1orf109,NKAIN1,FAM102A,NMNAT2,TROVE2,ZFP91" MicroRNA hsa-miR-1255b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-05 3.02E-01 6.37E-05 5.86E-04 16 102 "TAOK1,GAS7,CPS1,ST18,SPATA2,C8orf37,RAPGEF1,KAT7,GPR137C,NCR3LG1,C1orf109,NKAIN1,FAM102A,NMNAT2,TROVE2,ZFP91" MicroRNA hsa-miR-655-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.46E-05 3.07E-01 6.46E-05 5.95E-04 18 124 "NRXN3,ZNF385A,SEC14L5,TBC1D5,DBT,FAM198B,NCKAP1,DDX19B,TJAP1,NAP1L1,SLC11A2,PIK3CD,PACSIN1,PPP3CC,QDPR,PGBD4,TAB2,CLDND1" MicroRNA hsa-miR-1294:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.50E-05 3.09E-01 6.50E-05 5.99E-04 17 113 "CFL2,ZNF385A,EDN1,BSCL2,POLL,KIF3A,NUCB2,OLR1,DIRAS2,RDX,TTLL7,C12orf49,SP2,KIAA0930,CBX5,RBFOX2,MEAF6" MicroRNA hsa-miR-4278:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.52E-05 3.10E-01 6.53E-05 6.02E-04 10 44 "MTA3,EVI5L,PKD1,PTPA,SETD5,SHMT2,SON,NMNAT2,ERC1,THRA" MicroRNA hsa-miR-3147:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.61E-05 3.15E-01 6.64E-05 6.11E-04 12 62 "XKR4,LDHD,CTIF,DNAJC6,ST8SIA3,GPR61,PDE3A,MINDY2,FAM126B,STAU1,SULF2,NSD1" MicroRNA hsa-miR-7704:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.81E-05 3.26E-01 6.87E-05 6.33E-04 11 53 "CPNE5,IP6K1,PLEKHM1,TUBB4A,FLYWCH1,KCNH1,COMMD5,TBC1D25,ZNF426,RGS12,ARC" MicroRNA hsa-miR-1269b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-05 3.27E-01 6.88E-05 6.34E-04 9 36 "ESYT2,E2F6,EN2,CAB39,RNF165,OPHN1,KCTD15,FITM2,MYO18A" MicroRNA hsa-miR-4529-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-05 3.27E-01 6.88E-05 6.34E-04 9 36 "TTYH1,ABAT,E2F6,EN2,RNF165,ZIC5,OPHN1,FITM2,MYO18A" MicroRNA hsa-miR-4632-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-05 3.27E-01 6.88E-05 6.34E-04 9 36 "PLEKHG5,FOXK1,CCPG1,KMT2C,APC2,RASL10A,BRSK1,RADIL,SZT2" MicroRNA hsa-miR-4740-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-05 3.27E-01 6.88E-05 6.34E-04 9 36 "ESYT2,CBARP,MICAL2,E2F6,CAB39,TDRKH,RNF165,OPHN1,KCTD15" MicroRNA hsa-miR-5000-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-05 3.36E-01 7.06E-05 6.50E-04 13 72 "LDHD,KALRN,ARHGAP22,MICAL2,ENPP6,HMGB1,KCNN1,GPR137C,PKM,SMOX,ZC3H4,SLC44A1,WBP2" MicroRNA hsa-miR-128-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-05 3.36E-01 7.06E-05 6.50E-04 13 72 "PLEKHG5,GRAMD1B,TOM1,DOT1L,NKX6-2,SEPT9,NEUROD2,NFIX,NKX2-2,LIMS2,MPRIP,STX1A,DNMBP" MicroRNA hsa-miR-876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-05 3.36E-01 7.06E-05 6.50E-04 13 72 "TAOK1,ABCG2,PYGO1,TOMM20,EPB41L1,CBX1,MAOB,MAT2A,P2RX7,P2RY1,ATXN1,ALG1,TPM4" MicroRNA hsa-miR-4436a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-05 3.36E-01 7.06E-05 6.50E-04 13 72 "LDHD,KALRN,ARHGAP22,MICAL2,ENPP6,HMGB1,KCNN1,GPR137C,PKM,SMOX,ZC3H4,SLC44A1,WBP2" MicroRNA hsa-miR-4323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.99E-05 3.37E-01 7.08E-05 6.52E-04 14 82 "TEX22,BCL2L2,TMEM184B,CS,SIRPA,ABCC5,ELAVL3,STMN1,NEXMIF,NRGN,RTKN,PKNOX2,RPL7L1,WIPF2" MicroRNA hsa-miR-6729-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.07E-05 3.41E-01 7.16E-05 6.60E-04 16 103 "SLC16A4,CBARP,HP1BP3,ANKFY1,TRMO,FUT9,RNPS1,KCNN3,CHST6,PDE4A,ALG9,ATAT1,AP4E1,ARL10,PPIL6,UBC" MicroRNA hsa-miR-5196-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.08E-05 3.41E-01 7.17E-05 6.60E-04 18 125 "TAOK1,NIPA1,CFAP410,KIAA1549L,KIF26A,PCDH17,GNAS,GRID1,GRM1,HMGB1,ZMAT4,ALG9,SEMA6D,BDP1,ERC1,ELOVL4,DAAM2,ZNF195" MicroRNA hsa-miR-3922-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.55E-05 3.68E-01 7.73E-05 7.12E-04 15 93 "GPAM,DBT,ST8SIA3,COQ7,CELF1,ZNF274,RAB30,FICD,HAS2,PKM,TNPO2,PTPA,SLC1A2,SP4,USP22" MicroRNA hsa-miR-3690:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-05 3.72E-01 7.80E-05 7.18E-04 12 63 "APBB2,RIMS4,EFNA3,ANKMY1,CAB39,CRCP,HMX1,C2orf72,STX1B,AGTPBP1,TGFBR3,WIPF2" MicroRNA hsa-miR-6853-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-05 3.72E-01 7.80E-05 7.18E-04 12 63 "BRAP,SORCS2,TAOK1,C1orf52,PLEKHA1,FOXG1,SAMD14,ZNF426,CCDC25,TROVE2,NR2E1,UBE3A" MicroRNA hsa-miR-6894-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-05 3.72E-01 7.80E-05 7.18E-04 12 63 "TAOK1,USP37,PRX,ARSE,IP6K1,CTIF,GJB1,RAPGEF1,OLR1,RAB5B,HSPA4L,GPRIN3" MicroRNA hsa-miR-499b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-05 3.72E-01 7.80E-05 7.18E-04 12 63 "PLEKHG5,CAPRIN2,CACNA1B,LIN54,DNAH9,MAMLD1,FEM1B,SRRM1,NAT8L,MDM4,FXYD6,FIGN" MicroRNA hsa-miR-510-5p:Functional MTI Functional MTI miRTarbase 6.75E-05 3.79E-01 7.96E-05 7.33E-04 20 149 "SLC24A4,CDC14B,ZNF583,CBFA2T2,GPR37L1,NRXN3,NCOR2,ELMSAN1,ZNF585B,GPR75,BVES,IBA57,KCNJ5,MAT2A,NUCB1,PPP2R5E,MTMR10,ELP2,SLC2A5,SPIRE1" MicroRNA hsa-miR-3197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.78E-05 3.81E-01 7.99E-05 7.36E-04 10 45 "STOML1,NCOR2,DUSP9,GPR75,KAT7,IGF1,A2ML1,SEPHS1,SLC37A2,EVI5" MicroRNA hsa-miR-6889-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-05 3.86E-01 8.10E-05 7.46E-04 14 83 "CLK4,AMER3,KBTBD11,CELF1,B4GALNT4,KCNJ11,HSPA4L,AJAP1,USP22,TMEM151B,DICER1,ZNF70,SLC30A4,GDPD5" MicroRNA hsa-miR-5087:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.88E-05 3.86E-01 8.10E-05 7.46E-04 14 83 "CACNA1A,FEM1B,ENPP6,DLC1,ATP8A2,SLC2A6,ALDH1L2,NCR3LG1,MARCH1,SEPHS1,TNS1,VSNL1,ZNF781,HNRNPA3" MicroRNA hsa-miR-4491:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-05 3.90E-01 8.16E-05 7.52E-04 13 73 "CA8,LRWD1,SRSF11,CRCP,SESN3,MYCN,GPR137C,SMTN,PEG10,ATMIN,ITGB3BP,TRPC3,BCL2L13" MicroRNA hsa-miR-4657:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-05 3.90E-01 8.16E-05 7.52E-04 13 73 "CA8,LRWD1,SRSF11,CRCP,SESN3,MYCN,GPR137C,SMTN,PEG10,ATMIN,ITGB3BP,TRPC3,BCL2L13" MicroRNA hsa-miR-4712-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.94E-05 3.90E-01 8.16E-05 7.52E-04 13 73 "OSBPL3,IST1,ELAVL2,MSANTD4,MMP16,SESN3,OGDH,OLA1,PPP2R5E,TRIM67,ZFP91,RPL7L1,PMEPA1" MicroRNA hsa-miR-371b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.91E-01 8.18E-05 7.54E-04 11 54 "ADD1,SRARP,FLT1,AFF1,XRRA1,ADAM22,ZC3H12B,TMEM231,UEVLD,ATXN1,TPM3" MicroRNA hsa-miR-3157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.91E-01 8.18E-05 7.54E-04 11 54 "TEX22,ATP2A2,RGS6,CRCP,GPD1,GPR45,HPR,MAPT,XRRA1,OCIAD1,TRIM67" MicroRNA hsa-miR-33b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.91E-01 8.18E-05 7.54E-04 11 54 "ADD1,STX16,CLOCK,YTHDC1,HSPA12B,WAC,FLT1,AFF1,ADAM22,ZC3H12B,UEVLD" MicroRNA hsa-miR-6799-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.91E-01 8.18E-05 7.54E-04 11 54 "ARHGEF2,CPS1,FAM107A,KCNK10,CAMKV,ATXN1,TRIM67,CPEB4,GDPD5,XKR7,VANGL2" MicroRNA hsa-miR-3173-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.96E-05 3.91E-01 8.18E-05 7.54E-04 11 54 "ARHGEF2,CPS1,FAM107A,KCNK10,CAMKV,ATXN1,TRIM67,CPEB4,GDPD5,XKR7,VANGL2" MicroRNA hsa-miR-4738-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.02E-05 3.94E-01 8.25E-05 7.60E-04 8 29 "CPNE5,NIPBL,TMEM164,GNG4,GPT2,SAMD5,FTO,SGK1" MicroRNA hsa-miR-127-3p:Functional MTI Functional MTI miRTarbase 7.02E-05 3.94E-01 8.25E-05 7.60E-04 8 29 "USP35,SEPT7,NBEA,KCNA6,MAPK4,SEC31A,RGMA,ACTR3B" MicroRNA "CACGTTT,MIR-302A:MSigDB" "CACGTTT,MIR-302A:MSigDB" MSigDB 7.02E-05 3.94E-01 8.25E-05 7.60E-04 8 29 "DOC2A,PUM1,FAM131B,NBEA,LRRC8A,SSBP2,DPYSL5,CPNE4" MicroRNA hsa-miR-662:PITA hsa-miR-662:PITA_TOP PITA 7.33E-05 4.12E-01 8.62E-05 7.94E-04 7 22 "APP,BCL2L2,CNTNAP2,CHIC1,ZNF532,SGK1,TNS1" MicroRNA hsa-miR-4999-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.35E-05 4.13E-01 8.63E-05 7.95E-04 9 37 "MARCH4,SRSF11,DNAJB6,HIPK3,ZNF589,SUCO,SOWAHA,INKA2,SNX27" MicroRNA hsa-miR-4436b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.44E-05 4.18E-01 8.73E-05 8.04E-04 15 94 "GRAMD1B,MAP7,VCAN,NOS1AP,TIAM2,CALN1,HEYL,RCAN2,MIER3,HPR,SESN3,SETD5,ATXN2,TUBB2A,PPP1R3F" MicroRNA hsa-miR-6740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.77E-05 4.36E-01 9.12E-05 8.40E-04 12 64 "FOXK1,CA8,VXN,PITPNM3,FEM1B,ABI2,PGBD4,BDP1,SRPK2,ERBIN,ACSBG1,EXOC7" MicroRNA hsa-miR-4733-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.87E-05 4.42E-01 9.24E-05 8.51E-04 14 84 "SLC24A4,PYGO1,SPATA2,YTHDC1,HEYL,RAB30,SHC3,MYO5A,OLR1,SCP2,PEX26,TMCC1,ZNF621,VANGL2" MicroRNA hsa-miR-4677-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.03E-05 4.51E-01 9.42E-05 8.67E-04 13 74 "SDC3,CHRDL1,RASGRP1,APC2,TOMM40L,KLF12,HSP90AA1,TTLL7,FNBP1,SEPT8,KLHL7,CBX5,TPD52L2" MicroRNA hsa-miR-6796-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.03E-05 4.51E-01 9.42E-05 8.67E-04 13 74 "TRMT9B,AMPD3,TMEM184B,PYGO1,ELN,MAP4,PLEC,SLC25A23,SDK2,ATXN2,SMTN,PEG10,NACC2" MicroRNA hsa-miR-296-5p:Functional MTI Functional MTI miRTarbase 8.03E-05 4.51E-01 9.42E-05 8.67E-04 13 74 "TRIM41,SUMF2,TOGARAM2,TOM1,ELAVL3,MTSS1L,FGFR1,ADAMTS13,ZDHHC15,NFIX,ZDHHC8,S100B,VAMP1" MicroRNA hsa-miR-6720-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.27E-05 4.65E-01 9.70E-05 8.93E-04 10 46 "SLC24A4,TXNDC16,RNF14,MRNIP,TUBD1,ATOH8,METTL21A,MAPK8IP3,CBX5,CFAP298" MicroRNA hsa-miR-1256:Non-Functional MTI Non-Functional MTI miRTarbase 8.27E-05 4.65E-01 9.70E-05 8.93E-04 10 46 "OGT,ARHGEF7,CHD5,EID2B,ZIC5,POU3F2,TRIM68,SALL1,SLC6A8,SMARCE1" MicroRNA hsa-miR-99b:mirSVR_highEffct hsa-miR-99b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 8.27E-05 4.65E-01 9.70E-05 8.93E-04 10 46 "CYBB,SLC29A4,EML1,FGFR3,TUBGCP4,MIER3,MBNL1,CAND2,PRRC2C,SLC44A1" MicroRNA hsa-miR-3137:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-05 4.66E-01 9.73E-05 8.96E-04 11 55 "MIER1,RASL11B,AKAP12,SOCS5,FAM131B,DNAJB6,ZIC5,IL6ST,NPTX2,KSR2,TMEM178B" MicroRNA hsa-miR-3680-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-05 4.66E-01 9.73E-05 8.96E-04 11 55 "ZNF578,ZNF589,MPP6,ELOVL5,USP51,SHISA6,SYTL4,SESN3,TMOD2,USP22,AGMO" MicroRNA hsa-miR-135b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-05 4.66E-01 9.73E-05 8.96E-04 11 55 "ARID1A,EVI5L,TOGARAM2,KCND1,NPTX2,GPR137C,SETD5,SON,ZNF423,THRA,ZNF138" MicroRNA hsa-miR-635:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.30E-05 4.66E-01 9.73E-05 8.96E-04 11 55 "SEMA7A,ARHGDIA,SUMF2,ELAVL3,EPB41,CELF1,CNNM2,DRAXIN,SLC30A10,ZKSCAN3,LINC00632" MicroRNA hsa-miR-6782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.42E-05 4.73E-01 9.86E-05 9.08E-04 15 95 "PNMA8B,MTA3,MARCH4,IP6K1,DMTN,POLL,CECR2,OGDH,PLEC,SETD5,MYH14,SP2,CAMTA2,SEPT8,USP22" MicroRNA "TGCACGA,MIR-517A:MSigDB" "TGCACGA,MIR-517A:MSigDB" MSigDB 8.61E-05 4.84E-01 1.01E-04 9.28E-04 6 16 "SLITRK1,BSN,DBN1,PTK2B,TMCC1,CBLN2" MicroRNA hsa-miR-147b:PITA hsa-miR-147b:PITA_TOP PITA 8.61E-05 4.84E-01 1.01E-04 9.28E-04 6 16 "PPARGC1A,CELF3,CAMK2N2,RGS7,SLC44A1,NDRG4" MicroRNA "TGCACGA,MIR-517C:MSigDB" "TGCACGA,MIR-517C:MSigDB" MSigDB 8.61E-05 4.84E-01 1.01E-04 9.28E-04 6 16 "SLITRK1,BSN,DBN1,PTK2B,TMCC1,CBLN2" MicroRNA hsa-miR-3176:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.64E-05 4.85E-01 1.01E-04 9.31E-04 16 106 "GPAM,DBT,BLOC1S6,ST8SIA3,COQ7,CELF1,ZNF274,RAB30,FICD,HAS2,PKM,TNPO2,PTPA,SLC1A2,SP4,USP22" MicroRNA hsa-miR-153-3p:Functional MTI Functional MTI miRTarbase 8.99E-05 5.05E-01 1.05E-04 9.68E-04 14 85 "ARID1A,USP28,USP6NL,ZEB2,HMGB1,NFE2L2,P2RY1,SATB1,SNCA,ZBTB43,SS18,SEPT8,RPL7L1,FXR1" MicroRNA hsa-miR-523:PITA hsa-miR-523:PITA_TOP PITA 9.04E-05 5.08E-01 1.06E-04 9.73E-04 4 6 "CTNND2,ZIC4,MYT1,SF1" MicroRNA hsa-miR-551b-3p:TargetScan hsa-miR-551b-3p TargetScan 9.04E-05 5.08E-01 1.06E-04 9.73E-04 4 6 "CTIF,HEYL,ERBB4,MEF2C" MicroRNA hsa-miR-551a:TargetScan hsa-miR-551a TargetScan 9.04E-05 5.08E-01 1.06E-04 9.73E-04 4 6 "CTIF,HEYL,ERBB4,MEF2C" MicroRNA hsa-miR-1295:PITA hsa-miR-1295:PITA_TOP PITA 9.04E-05 5.08E-01 1.06E-04 9.73E-04 4 6 "EGR3,TCEAL5,FAT3,SOX6" MicroRNA hsa-miR-301b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-05 5.11E-01 1.06E-04 9.78E-04 12 65 "NDRG2,ERBB2,TLX1,SYTL4,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,TMEM151B,ARL10,ZNF708" MicroRNA hsa-miR-651-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-05 5.11E-01 1.06E-04 9.78E-04 12 65 "CNN3,KIAA0408,SPATA2,ANKRD46,HSPA12B,ADAM28,CHIC1,MDM4,ZC3H12B,OLR1,TCF7L2,TUBB2A" MicroRNA hsa-miR-5687:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.15E-05 5.14E-01 1.07E-04 9.84E-04 8 30 "MAP4K4,CRCP,KIF3A,GPSM2,PRKAB2,FNIP1,GSE1,RNF146" MicroRNA hsa-miR-564:PITA hsa-miR-564:PITA_TOP PITA 9.20E-05 5.17E-01 1.07E-04 9.89E-04 9 38 "SDE2,PPFIA3,CABP1,PHC2,PTCH1,SP2,ZIC2,ZIC3,TMEM63C" MicroRNA hsa-miR-6766-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.20E-05 5.17E-01 1.07E-04 9.89E-04 9 38 "PUM1,RAB30,RASSF8,MBNL1,MDM4,PCMT1,ROBO1,SATB2,CLIP2" MicroRNA hsa-miR-5702:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-05 5.20E-01 1.08E-04 9.96E-04 13 75 "OGT,CD81,UBXN2A,SLC12A6,ANKRD46,BSCL2,SCRG1,NKD1,KCNN1,HSPA4L,SPART,FAM168A,TPD52L2" MicroRNA hsa-miR-323a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.26E-05 5.20E-01 1.08E-04 9.96E-04 13 75 "SDE2,NLGN4X,SEMA7A,CANX,CBR1,SOCS5,F5,STMN1,SESN3,GPSM2,FNDC3A,TRPS1,ZXDA" MicroRNA hsa-miR-146a-5p:Functional MTI Functional MTI miRTarbase 9.82E-05 5.52E-01 1.15E-04 1.06E-03 24 202 "PLEKHG5,OSBPL1A,NUMB,NSL1,MICAL2,EGFR,ERBB4,MRPL10,COPS8,KDM2B,GPM6B,L1CAM,MPP2,MYO6,NOS1,KCTD15,ROBO1,ELP2,RUFY2,SOX2,SPP1,TMEM136,TLR4,TMPRSS5" MicroRNA hsa-miR-4676-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.86E-05 5.54E-01 1.15E-04 1.06E-03 11 56 "BEND6,HACE1,TXNDC16,HEYL,DOT1L,GFRA1,SEMA6D,TMCC1,ZNF621,CLASP1,WNK1" MicroRNA hsa-miR-3613-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-04 5.64E-01 1.17E-04 1.08E-03 10 47 "ARID1A,XKR4,MTX3,VPS13B,KATNAL1,SARAF,NTNG2,NCR3LG1,NTNG1,NHSL1" MicroRNA hsa-miR-5684:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-04 5.64E-01 1.17E-04 1.08E-03 10 47 "SIRPA,SACS,ATP13A4,PLD5,KIT,AFF1,ZYG11B,PEG10,TMEM178B,TRPC3" MicroRNA hsa-miR-7112-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-04 5.64E-01 1.17E-04 1.08E-03 10 47 "INSYN2B,LONRF2,KIAA1549L,COL9A2,ANKFY1,ZNF274,NUMA1,USP47,SALL1,DAAM2" MicroRNA hsa-miR-3691-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-04 5.64E-01 1.17E-04 1.08E-03 10 47 "CA8,CD86,NRXN1,ST18,MRPL10,CSPG5,NXPH3,PACSIN2,HEY2,TPM4" MicroRNA hsa-miR-6886-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-04 5.96E-01 1.24E-04 1.14E-03 12 66 "ATP2A2,CRY2,SOCS5,GAPVD1,TXNL4A,FAM107A,MAPT,NPTX2,SNRK,OCIAD1,BSDC1,INKA2" MicroRNA hsa-miR-8059:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-04 5.96E-01 1.24E-04 1.14E-03 12 66 "ABI2,VPS26C,GTF2IRD2,TACC2,PHKG1,KCTD15,PRKAB2,SCN4B,COPZ1,NFASC,TAB2,TUBB2A" MicroRNA hsa-miR-4471:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.06E-04 5.96E-01 1.24E-04 1.14E-03 12 66 "ABI2,VPS26C,GTF2IRD2,TACC2,PHKG1,KCTD15,PRKAB2,SCN4B,COPZ1,NFASC,TAB2,TUBB2A" MicroRNA hsa-miR-3605-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-04 6.09E-01 1.26E-04 1.16E-03 16 108 "ADAR,ANK1,GAPVD1,TOMM20,SYNCRIP,KCND3,KIF5A,NUCB2,GPR137C,ZNF426,PPP2R5E,MTMR10,C1orf109,MRAS,PEG10,TPM1" MicroRNA hsa-miR-3674:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.08E-04 6.09E-01 1.26E-04 1.16E-03 16 108 "RNF157,ARNTL,MTMR9,BAG4,TOGARAM2,SEC14L5,IP6K1,MTX3,SLC2A6,HSP90AA1,LAYN,GPR137C,BTBD3,PUM2,NSD2,ZNF138" MicroRNA hsa-miR-3151-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-04 6.42E-01 1.33E-04 1.22E-03 9 39 "ELFN2,ADD2,CFL2,OSBPL3,NOS1AP,ARHGAP12,HUNK,RPL7L1,UGT8" MicroRNA hsa-miR-378c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-04 6.42E-01 1.33E-04 1.22E-03 9 39 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,SEC31A,ANO4,CELF4" MicroRNA hsa-miR-6731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.14E-04 6.42E-01 1.33E-04 1.22E-03 9 39 "INTS2,OSBPL1A,CCDC144A,SIRPA,GABRB1,GABRG2,SYT17,SHISA6,HNRNPA3" MicroRNA "GGCAGAC,MIR-346:MSigDB" "GGCAGAC,MIR-346:MSigDB" MSigDB 1.14E-04 6.42E-01 1.33E-04 1.22E-03 9 39 "OGT,CALN1,AFF2,GRM7,LRRTM1,MBNL1,KCTD15,CCDC136,SF1" MicroRNA hsa-miR-892c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.17E-04 6.55E-01 1.36E-04 1.25E-03 11 57 "BEND6,HACE1,TXNDC16,HEYL,DOT1L,GFRA1,SEMA6D,TMCC1,ZNF621,CLASP1,WNK1" MicroRNA hsa-miR-126-3p:Functional MTI Functional MTI miRTarbase 1.17E-04 6.55E-01 1.36E-04 1.25E-03 11 57 "PITPNC1,TOM1,FOXO3,PIK3R1,RGS3,SOX2,TCF4,TEK,SIRT1,CADM1,EVI5" MicroRNA hsa-miR-423-3p:TargetScan hsa-miR-423-3p TargetScan 1.18E-04 6.63E-01 1.37E-04 1.27E-03 5 11 "CINP,GBX2,MYO9A,ARFGAP1,KCTD2" MicroRNA "AACGGTT,MIR-451:MSigDB" "AACGGTT,MIR-451:MSigDB" MSigDB 1.18E-04 6.63E-01 1.37E-04 1.27E-03 5 11 "OGT,FMNL3,CAB39,MINDY2,EMSY" MicroRNA hsa-miR-4640-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-04 6.80E-01 1.41E-04 1.30E-03 10 48 "PNMA8B,GOLGA7B,ARRB1,FOXK1,CYBB,PHF19,CHST15,KIRREL1,SCN2B,NFASC" MicroRNA hsa-miR-6859-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.21E-04 6.80E-01 1.41E-04 1.30E-03 10 48 "GPRIN1,ARRB1,DNAJB5,CYBB,FGFR1OP2,MFAP3L,FAM120B,ZDHHC8,SF1,XKR7" MicroRNA hsa-miR-4653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-04 6.92E-01 1.43E-04 1.32E-03 12 67 "ARHGDIA,EIF1,TRAF3IP2,GLUL,RAB40B,MAT2A,PXK,FAM161B,ATXN1,AGTPBP1,ZNF384,TRPC3" MicroRNA hsa-miR-129-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-04 6.92E-01 1.43E-04 1.32E-03 12 67 "NUMBL,DNAJB5,RGS6,GAPVD1,DUSP9,E2F5,NPTN,CACFD1,KCNB1,NPTX2,DDR2,PDCD2" MicroRNA hsa-miR-450a:PITA hsa-miR-450a:PITA_TOP PITA 1.27E-04 7.16E-01 1.48E-04 1.36E-03 6 17 "ZNF608,GPR158,KMT5B,MEIS1,MEIS2,KANSL1" MicroRNA "ATGCACG,MIR-517B:MSigDB" "ATGCACG,MIR-517B:MSigDB" MSigDB 1.27E-04 7.16E-01 1.48E-04 1.36E-03 6 17 "CABP7,CAMK2G,NRXN1,MEIS2,TBX15,PRDM8" MicroRNA hsa-miR-886-3p:PITA hsa-miR-886-3p:PITA_TOP PITA 1.27E-04 7.16E-01 1.48E-04 1.36E-03 6 17 "SDE2,GOLGA7B,MARK4,NFIX,NLGN3,THRA" MicroRNA hsa-miR-6090:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.32E-04 7.42E-01 1.53E-04 1.41E-03 14 88 "ELFN2,FMNL3,ADGRG1,E2F6,ANKFY1,PRRC2B,NEGR1,NPTX2,PKD1,PTPA,CAMTA2,SEPT8,RPRM,VAV2" MicroRNA hsa-miR-6732-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-04 7.63E-01 1.58E-04 1.45E-03 15 99 "ANK1,EVI5L,GRIN2D,KCNK3,PKM,PTPA,KANSL1,SHMT2,SON,NMNAT2,ERC1,THRA,ZFP91,TPM3,RICTOR" MicroRNA hsa-miR-521:Functional MTI Functional MTI miRTarbase 1.36E-04 7.65E-01 1.58E-04 1.46E-03 7 24 "IPCEF1,PLEKHM1,INPP5B,KANSL1,CARF,LRRC55,RHBDL3" MicroRNA hsa-miR-99a-5p:Functional MTI Functional MTI miRTarbase 1.37E-04 7.70E-01 1.59E-04 1.47E-03 18 133 "ATP1A1,DOCK11,MTMR3,FAM171B,PUM1,DDX46,MED12,FGFR3,TPPP3,NFU1,GNAL,N6AMT1,RAVER2,FOXRED2,DDHD1,RUNDC3B,RPL7L1,SPIRE1" MicroRNA hsa-miR-491-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.37E-04 7.72E-01 1.59E-04 1.47E-03 11 58 "PTCH2,CDC27,RAB3C,ST6GALNAC3,GRM8,ZNF678,KCNJ10,MBNL1,ABCB1,ATXN1,CPEB4" MicroRNA hsa-miR-191-5p:Functional MTI Functional MTI miRTarbase 1.40E-04 7.87E-01 1.62E-04 1.50E-03 13 78 "USP37,SPATA2,GOLGA7,EMX2,MTSS1L,ACSS1,TJAP1,MDM4,HNRNPM,TNPO2,DCUN1D2,SATB1,LRRC8A" MicroRNA hsa-miR-4732-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.40E-04 7.87E-01 1.62E-04 1.50E-03 13 78 "RNF157,SEC14L5,ST6GALNAC3,HSP90AA1,LAYN,KSR2,ZIK1,PRIMA1,ALG1,DOK6,TUBB2A,NSD2,ZNF138" MicroRNA hsa-miR-4508:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.41E-04 7.91E-01 1.63E-04 1.50E-03 9 40 "AMH,PRX,ARHGDIA,BRSK2,RGS6,IRAK3,ZNF426,PEX26,TMEM63C" MicroRNA hsa-miR-6813-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-04 8.02E-01 1.66E-04 1.52E-03 12 68 "EIF4G3,DCAF8,DNAJB6,ITPKB,ARHGAP12,MAN2A2,PIK3C2A,C12orf49,CLUAP1,AJAP1,ZNF34,ZNF70" MicroRNA hsa-miR-301a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.43E-04 8.02E-01 1.66E-04 1.52E-03 12 68 "NDRG2,ERBB2,TLX1,SYTL4,P2RX7,PRKAB2,SH3TC2,ZFP1,ZNF415,TMEM151B,ARL10,ZNF708" MicroRNA hsa-miR-1284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-04 8.15E-01 1.68E-04 1.55E-03 10 49 "MTA3,SPAG9,NFS1,KIAA1549L,RCAN2,PRRC2B,INPP5B,KCNK10,PKN2,KIF13A" MicroRNA hsa-miR-4703-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-04 8.15E-01 1.68E-04 1.55E-03 10 49 "BACH1,DNAL1,ANKRD46,GORAB,GABRB3,TCERG1,AP4S1,HSP90AA1,SCP2,CADM1" MicroRNA hsa-miR-4464:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.49E-04 8.39E-01 1.73E-04 1.59E-03 14 89 "MTUS1,KIF6,CHD5,ENPP6,ERBB2,GLI2,SLC2A6,ELOVL5,GLIPR1L2,CNNM2,MARCH1,SEPHS1,TNS1,WRN" MicroRNA hsa-miR-24-2-5p:Functional MTI Functional MTI miRTarbase 1.50E-04 8.43E-01 1.74E-04 1.60E-03 8 32 "PNKD,ABI2,ELOVL5,NFIX,TMEM231,SP2,TPM4,DHX33" MicroRNA hsa-miR-210-3p:TargetScan hsa-miR-210-3p TargetScan 1.50E-04 8.43E-01 1.74E-04 1.60E-03 8 32 "ELFN2,CPEB2,EFNA3,SCARA3,MEX3B,NFIX,CDIP1,HIF3A" MicroRNA hsa-miR-6803-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-04 8.46E-01 1.74E-04 1.61E-03 16 111 "ARHGDIA,BCL7A,CLU,ZNF385A,DBT,DOT1L,GRIK2,NLE1,DIRAS2,HSD11B1L,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,MEAF6" MicroRNA hsa-miR-152-3p:Functional MTI Functional MTI miRTarbase 1.53E-04 8.60E-01 1.77E-04 1.63E-03 20 158 "ALCAM,TRMT9B,STX16,CCKBR,CLOCK,CSF1,FGFR3,NEURL4,TNRC6A,HSP90AA1,ZIC5,SESN3,CNOT4,NPTX1,BTBD3,CDK19,INKA2,DICER1,PLPP4,FXR1" MicroRNA hsa-miR-2053:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.60E-04 8.99E-01 1.85E-04 1.70E-03 13 79 "XKR4,G3BP2,SEMA3D,EIF5,STARD3NL,NCALD,TUBA1B,SARAF,HLF,KCNN3,SESN3,DDR2,NAXD" MicroRNA hsa-miR-320d:Functional MTI Functional MTI miRTarbase 1.60E-04 8.99E-01 1.85E-04 1.70E-03 13 79 "ADD1,SEMA7A,TNRC6C,C2CD2,SYNCRIP,SRCAP,RBPJ,HSPA4L,TAL1,ARL10,RBFOX2,TPD52,SLC38A1" MicroRNA hsa-miR-5004-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.27E-01 1.91E-04 1.76E-03 12 69 "PLEKHM1,SCML2,ANKFY1,ELP2,GALNT10,SLIT1,AJAP1,ZC3H4,THRA,ERCC6L2,TNS1,ZNF74" MicroRNA hsa-miR-219a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.27E-01 1.91E-04 1.76E-03 12 69 "ZNF385A,CTNND1,USP6NL,CELSR3,FICD,HMGB1,PLD5,IL6R,SESN3,NKAIN1,MTMR14,PMEPA1" MicroRNA hsa-miR-513b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.27E-01 1.91E-04 1.76E-03 12 69 "PHF12,ATP1B3,ARHGEF4,DPP6,RCAN2,SESN3,PXK,PTPRB,NSD1,WBP2,TOM1L2,JMJD1C" MicroRNA hsa-miR-3606-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.27E-01 1.91E-04 1.76E-03 12 69 "APP,CBR1,BAG4,DCTN4,OCRL,KANSL1,ROBO1,KIF27,TRA2B,SLC6A8,AHCYL2,ZDHHC20" MicroRNA hsa-miR-6804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-04 9.27E-01 1.91E-04 1.76E-03 12 69 "PTCHD1,DST,CFAP410,PPP1R16B,ELAVL2,SIGLEC8,MTHFD2,PRRC2B,AGBL5,IBA57,GLDN,ZBTB43" MicroRNA hsa-miR-4422:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-04 9.41E-01 1.93E-04 1.78E-03 16 112 "MTA3,KIAA0408,DCAF8,F3,ELOVL5,NEGR1,CCDC80,BLOC1S2,PDE4D,PDPK1,SDK2,SNRK,KLHL11,SEC31A,SON,HECW1" MicroRNA hsa-miR-4477b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-04 9.48E-01 1.95E-04 1.80E-03 14 90 "SDE2,TEX22,OSBPL6,TAOK1,CAPRIN2,MYADM,ELMSAN1,CAB39,COMMD5,PCMT1,RUFY2,SEPT3,CRB1,TPM4" MicroRNA hsa-miR-6509-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-04 9.48E-01 1.95E-04 1.80E-03 14 90 "PNMA8B,GRAMD1B,NOS1AP,TIAM2,CALN1,RCAN2,MIER3,SESN3,PPP3CB,ATXN2,TUBB2A,ZNF138,WNK1,PPP1R3F" MicroRNA hsa-miR-1306:mirSVR_highEffct hsa-miR-1306:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.71E-04 9.59E-01 1.97E-04 1.82E-03 15 101 "AIF1L,FAM198B,SMC2,MSTN,BRD8,GRM7,IDH3B,MOBP,PCSK5,CEP41,ASRGL1,SLA,ADGRL3,TPCN2,TIAM1" MicroRNA hsa-miR-503-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.73E-01 2.00E-04 1.84E-03 10 50 "BRAP,ZFYVE9,TMEM184B,CSNK1G3,ZC3H11A,EGR3,C8orf37,LYVE1,L1CAM,NSD2" MicroRNA hsa-miR-8075:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.73E-01 2.00E-04 1.84E-03 10 50 "CANX,RNF165,MBNL1,PDGFRA,PDYN,FAM98B,PFKP,SCN7A,PEAR1,TOM1L2" MicroRNA hsa-miR-5571-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.73E-01 2.00E-04 1.84E-03 10 50 "RGS6,TNK2,FREM1,NELL2,KANSL1,FITM2,SCN2B,CLUAP1,ADAMTS17,ZNF34" MicroRNA hsa-miR-660-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.73E-04 9.73E-01 2.00E-04 1.84E-03 10 50 "EIF1,ATP13A4,ZHX1,XRRA1,NAP1L1,PCSK2,TMLHE,ARHGEF12,XKR7,WNK3" MicroRNA hsa-miR-5739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.81E-04 1.00E+00 2.09E-04 1.92E-03 7 25 "CACNA1B,SCARB1,EPS15L1,MICAL2,TNRC6A,CHIC1,GPR173" MicroRNA hsa-miR-8057:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-04 1.00E+00 2.10E-04 1.93E-03 20 160 "XKR4,ESYT2,AKAP5,AKAP12,CRY2,GOLGA7,PCYOX1,PDLIM5,CRCP,DBF4,LIMS1,SMOX,ZYG11B,ZNF430,SLC8A1,POGZ,ZNF106,FBXL16,TRPS1,LINC00632" MicroRNA hsa-miR-3975:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-04 1.00E+00 2.10E-04 1.94E-03 13 80 "SLC24A4,CEP126,ARHGDIA,CCNT1,ZNF385A,CRY2,RIMS4,KIAA0408,PRRC2B,WDTC1,DDN,WNK1,URM1" MicroRNA hsa-miR-381-3p:Functional MTI Functional MTI miRTarbase 1.83E-04 1.00E+00 2.10E-04 1.94E-03 18 136 "SPAG9,MYOM2,COPB2,CLTC,HDAC4,SEMA4D,BRPF3,ZNF181,ZNF546,MBNL1,MID1,SLC36A4,PRKCB,OCIAD1,CNKSR2,RUFY2,SLC6A8,WNK1" MicroRNA "CTACTAG,MIR-325:MSigDB" "CTACTAG,MIR-325:MSigDB" MSigDB 1.83E-04 1.00E+00 2.11E-04 1.94E-03 6 18 "CELF1,TMEM206,FAM19A1,TMCC1,ANKRD28,RIMBP2" MicroRNA hsa-miR-652:PITA hsa-miR-652:PITA_TOP PITA 1.83E-04 1.00E+00 2.11E-04 1.94E-03 6 18 "AKAP6,NPTN,GABRB3,TNRC6A,KCNK2,ZFAND5" MicroRNA hsa-miR-1281:PITA hsa-miR-1281:PITA_TOP PITA 1.83E-04 1.00E+00 2.11E-04 1.94E-03 6 18 "CABP1,AGAP3,TNRC6A,SCRT2,PRKCG,PTPRD" MicroRNA hsa-miR-7976:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-04 1.00E+00 2.17E-04 2.00E-03 11 60 "CPS1,FAM107A,DDR2,CAMKV,ATXN1,TRIM67,CPEB4,TMEM136,GDPD5,XKR7,TMEM63C" MicroRNA hsa-miR-5009-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.89E-04 1.00E+00 2.18E-04 2.01E-03 8 33 "LRWD1,E2F6,HIPK3,EN2,RNF165,OPHN1,FITM2,MYO18A" MicroRNA hsa-miR-503:PITA hsa-miR-503:PITA_TOP PITA 1.90E-04 1.00E+00 2.19E-04 2.01E-03 12 70 "CSMD3,ANK3,CNTNAP1,PPFIA3,NOL4,BSN,EIF4G1,IGF1,MAPK3,ZNF423,CSMD1,CELF4" MicroRNA hsa-miR-876-3p:Functional MTI Functional MTI miRTarbase 1.90E-04 1.00E+00 2.19E-04 2.01E-03 12 70 "ARID1A,NDST3,ENTPD4,RUBCN,SIRPA,ELN,MDM4,MTRF1L,RBBP6,ROBO1,EMC1,PEG10" MicroRNA hsa-miR-138-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.90E-04 1.00E+00 2.19E-04 2.02E-03 14 91 "SERPINA3,PHF12,KIAA1549L,NOS1AP,DDX46,KBTBD11,RCAN2,TNRC6A,MBNL1,PPM1L,CCSER2,TRAPPC13,VPS13A,RPL7L1" MicroRNA "AGCGCAG,MIR-191:MSigDB" "AGCGCAG,MIR-191:MSigDB" MSigDB 1.94E-04 1.00E+00 2.23E-04 2.06E-03 5 12 "OGT,CHRD,MAGI1,EGR3,HMGB1" MicroRNA hsa-miR-886-5p:PITA hsa-miR-886-5p:PITA_TOP PITA 1.94E-04 1.00E+00 2.23E-04 2.06E-03 5 12 "FOXN3,DMPK,EGR3,CAMKK2,TBR1" MicroRNA "TCCGTCC,MIR-184:MSigDB" "TCCGTCC,MIR-184:MSigDB" MSigDB 1.94E-04 1.00E+00 2.23E-04 2.06E-03 5 12 "EPB41L5,ATXN2L,PRKCB,SLC6A9,SF1" MicroRNA hsa-miR-4740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-04 1.00E+00 2.25E-04 2.07E-03 17 125 "AS3MT,RNF157,ESYT2,AP1B1,PTBP2,HINFP,KIAA0408,DNAL1,RABGAP1L,TUBD1,EPB41L1,FDFT1,PCYOX1,KIAA1958,EID2B,CFAP298,GAN" MicroRNA hsa-miR-6759-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-04 1.00E+00 2.36E-04 2.18E-03 10 51 "ATM,PNKD,RABGAP1L,SEC23B,DDR2,CLDN11,PFKFB3,MINDY2,KLHL4,EML6" MicroRNA hsa-miR-596:Functional MTI Functional MTI miRTarbase 2.06E-04 1.00E+00 2.36E-04 2.18E-03 10 51 "TXNDC16,CANX,FBXL5,CALN1,VTI1B,ATP13A4,POLL,TRIM68,RXRA,INKA2" MicroRNA hsa-miR-345-5p:Functional MTI Functional MTI miRTarbase 2.06E-04 1.00E+00 2.36E-04 2.18E-03 10 51 "CCPG1,E2F6,RNFT2,METTL21A,NTRK3,KCTD15,NWD1,ZNF667,ZNF106,CBX5" MicroRNA hsa-miR-550b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.06E-04 1.00E+00 2.36E-04 2.18E-03 10 51 "NLGN4X,RUNX1T1,TUBD1,RAPGEF1,PPM1L,MOG,ZYG11B,DIP2A,DDHD1,URM1" MicroRNA hsa-miR-4717-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.07E-04 1.00E+00 2.38E-04 2.19E-03 13 81 "ADCY5,SHROOM2,WAC,CTNNA3,KCTD15,C11orf49,FAT3,PALLD,MAPK8IP3,TMEM178B,TCF7L2,NSD1,CADM2" MicroRNA hsa-miR-151b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.10E-04 1.00E+00 2.41E-04 2.22E-03 9 42 "ARHGDIA,BCL7A,CRMP1,PLEKHM1,GPER1,OGDH,RFX2,SLC6A1,CAMTA2" MicroRNA hsa-miR-4519:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-04 1.00E+00 2.46E-04 2.26E-03 14 92 "ELFN2,CASK,CSNK1E,OSBPL3,SOCS5,IP6K1,FEM1B,GNAS,CHIC1,ZNF680,SESN3,BDNF-AS,ZC3H14,ATXN2" MicroRNA hsa-miR-1289:Functional MTI Functional MTI miRTarbase 2.16E-04 1.00E+00 2.48E-04 2.28E-03 17 126 "TAOK1,AMH,SEMA7A,RGS6,DNAL1,CAMKK2,MPP2,ZNF426,ELP2,SCN2B,ELMOD1,HSPA4L,NUBPL,FAM126B,KIAA0930,ZNF708,SLC30A3" MicroRNA hsa-miR-5586-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-04 1.00E+00 2.50E-04 2.31E-03 12 71 "ABCD2,MIER1,PLEKHO1,TOMM40L,TMEM164,C15orf41,FAXC,NR3C1,ZFYVE27,NODAL,PPP2R5E,CCDC14" MicroRNA hsa-miR-129-2-3p:Functional MTI Functional MTI miRTarbase 2.18E-04 1.00E+00 2.50E-04 2.31E-03 12 71 "BCL2L2,NUMBL,DNAJB5,RGS6,GAPVD1,DUSP9,E2F5,NPTN,CACFD1,KCNB1,NPTX2,DDR2" MicroRNA hsa-miR-4760-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.18E-04 1.00E+00 2.50E-04 2.31E-03 12 71 "BARD1,CALM1,NIPBL,HIPK3,SLC35G1,KCNQ3,LIFR,PDE4D,MAGEL2,SYT4,TPD52,VANGL2" MicroRNA hsa-miR-1228*:mirSVR_highEffct hsa-miR-1228*:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.18E-04 1.00E+00 2.50E-04 2.31E-03 12 71 "AP2A2,AGT,CACNA1B,DDR1,SEZ6L2,CLEC18A,CNNM2,CASTOR1,SLC11A1,SORCS3,C11orf87,KLC2" MicroRNA hsa-miR-938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.20E-04 1.00E+00 2.52E-04 2.32E-03 11 61 "ATP2A2,NUMBL,CRY2,RGS6,SOCS5,NPTN,TXNL4A,FAM107A,MAPT,SNRK,OCIAD1" MicroRNA hsa-miR-126-3p.2:TargetScan hsa-miR-126-3p.2 TargetScan 2.37E-04 1.00E+00 2.71E-04 2.50E-03 7 26 "ANKRD44,PLXNA4,PDE4A,PIK3R1,CPEB4,PSD3,ADAMTS9" MicroRNA hsa-miR-3186-3p:mirSVR_highEffct hsa-miR-3186-3p:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.37E-04 1.00E+00 2.71E-04 2.50E-03 8 34 "CAP2,CELF1,FERMT2,GRIK2,PTOV1,SNRPN,PMS2CL,RGMA" MicroRNA hsa-miR-4259:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-04 1.00E+00 2.79E-04 2.57E-03 10 52 "CLU,CTNND1,SIRPA,DNAL1,SRCAP,TNRC6A,AP4S1,HSD11B1L,FAM168A,SF1" MicroRNA hsa-miR-1273d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.43E-04 1.00E+00 2.79E-04 2.57E-03 10 52 "ATP1B3,ELMSAN1,EIF1,DIPK1A,SLC6A17,SNX22,SON,SYT11,SEZ6L,VAV2" MicroRNA hsa-miR-3191-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-04 1.00E+00 2.86E-04 2.63E-03 12 72 "HCN2,DLGAP3,TPP1,TBPL1,SEPT9,GCK,SESN1,TLX1,PKM,POLR2F,SBF1,SIN3B" MicroRNA hsa-miR-6802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-04 1.00E+00 2.86E-04 2.63E-03 12 72 "C6orf89,API5,BARD1,ZNF445,GAPVD1,SRARP,GABRB3,GJB1,OLA1,SEC61A2,FAM126B,SP2" MicroRNA hsa-miR-1265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-04 1.00E+00 2.86E-04 2.63E-03 12 72 "PLEKHG5,TAOK1,CD81,WDPCP,ANKRD46,KIF5A,GPR137C,PDE3A,PPP2R5E,SETD5,MRAS,TUBB2A" MicroRNA hsa-miR-6750-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-04 1.00E+00 2.86E-04 2.63E-03 12 72 "PHF12,LDHD,TM9SF4,GTF2IRD2,CAMKK2,NPTX1,NPTX2,NRGN,SLC25A36,SMOC1,TUBB2A,MPPE1" MicroRNA hsa-miR-6822-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.50E-04 1.00E+00 2.86E-04 2.63E-03 12 72 "PHF12,LDHD,TM9SF4,GTF2IRD2,CAMKK2,NPTX1,NPTX2,NRGN,SLC25A36,SMOC1,TUBB2A,MPPE1" MicroRNA hsa-miR-591:Functional MTI Functional MTI miRTarbase 2.53E-04 1.00E+00 2.90E-04 2.67E-03 9 43 "ADD1,BSN,ZFYVE9,AASS,KATNAL1,KLHL23,ASTN2,ZEB1,ZMAT3" MicroRNA hsa-miR-3907:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-04 1.00E+00 2.90E-04 2.67E-03 9 43 "RNF157,CDC25B,TBPL1,CSNK1E,KLHL11,HUNK,AMER2,ZNF74,SSPN" MicroRNA hsa-miR-4752:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-04 1.00E+00 2.91E-04 2.68E-03 11 62 "LDHD,CA8,CD86,NRXN1,ST18,ZC3H11A,C8orf37,MYO18A,ZNF106,HEY2,TPM4" MicroRNA hsa-miR-629-5p:Functional MTI Functional MTI miRTarbase 2.55E-04 1.00E+00 2.91E-04 2.68E-03 11 62 "CFLAR,CSNK1E,RASSF8,NFYA,MTRF1L,PTPRB,RTKN,NCDN,ZEB1,AKTIP,PARD3" MicroRNA hsa-miR-4258:mirSVR_highEffct hsa-miR-4258:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.55E-04 1.00E+00 2.91E-04 2.68E-03 11 62 "NDRG2,ADAM15,CBR1,ARMCX4,NELFCD,AP4B1,NCKAP1L,MTR,NEUROD2,NEU4,WIPF1" MicroRNA hsa-miR-4665-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.56E-04 1.00E+00 2.92E-04 2.69E-03 6 19 "EPB41,PLD5,NRGN,OCIAD1,ZMAT3,MEAF6" MicroRNA hsa-miR-923:PITA hsa-miR-923:PITA_TOP PITA 2.56E-04 1.00E+00 2.92E-04 2.69E-03 6 19 "FMNL2,TRMT9B,SMG7,PPARGC1A,ROBO1,SYN2" MicroRNA hsa-miR-2392:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.63E-04 1.00E+00 3.01E-04 2.77E-03 18 140 "XKR4,ADAR,PLEKHG5,TAOK1,ANK1,PPP1R16B,TOMM20,BLOC1S6,WDPCP,ANKRD46,TRAF3IP2,TJAP1,KCND3,MTMR10,SETD5,MRAS,TUBB2A,MSRB3" MicroRNA hsa-miR-4799-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-04 1.00E+00 3.08E-04 2.84E-03 14 94 "ZBTB10,ZNF555,KIAA0408,ARHGAP32,TMEM170A,SARAF,DKK3,GCK,HNF4G,KITLG,PLEKHB2,FAM126B,TBCEL,TJP1" MicroRNA hsa-miR-4518:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.70E-04 1.00E+00 3.08E-04 2.84E-03 14 94 "ARID1A,MAP7,NCOR2,YTHDC1,SV2B,GABRA5,GPR75,PCSK2,KCTD15,PLEC,SMARCE1,DDN,CAMSAP2,PSD3" MicroRNA hsa-miR-3189-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-04 1.00E+00 3.26E-04 3.00E-03 12 73 "ARHGEF25,CCNT1,RAB3C,FRMPD4,DNAL1,CELF1,ZNF568,STX1B,SLC30A10,POGZ,TMEM178B,NACC2" MicroRNA hsa-miR-4539:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-04 1.00E+00 3.26E-04 3.00E-03 12 73 "ADCY2,CCAR2,ABCG2,TMEM184B,PYGO1,SPATA2,BEST3,PRKACB,SEC61A2,SLC30A10,KANSL3,ZC4H2" MicroRNA hsa-miR-7114-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-04 1.00E+00 3.26E-04 3.00E-03 12 73 "ADCY2,FOXK1,CD86,NRXN1,KIAA0040,KCNJ10,NOVA2,PPP2R5C,SHMT2,ARC,WNK1,WNK2" MicroRNA hsa-miR-4725-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.85E-04 1.00E+00 3.26E-04 3.00E-03 12 73 "CENPL,ANKMY1,TMEM164,SLC11A2,PDPK1,SH3TC2,PRRT2,KLHDC8A,COPZ1,SEPT3,ZC3H4,SZT2" MicroRNA hsa-miR-1322:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.87E-04 1.00E+00 3.27E-04 3.01E-03 10 53 "ATP1B3,PPP1R16B,GOLGA7,TUBA1B,MMADHC,NUDT21,KANSL1,C1orf109,ALG1,KCNK12" MicroRNA hsa-miR-616-3p:Functional MTI Functional MTI miRTarbase 2.87E-04 1.00E+00 3.27E-04 3.01E-03 10 53 "CARNS1,BBOX1,USP37,SFMBT2,CAPRIN2,DLGAP3,MRO,MIER3,CNNM2,RBM26" MicroRNA hsa-miR-4506:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.87E-04 1.00E+00 3.27E-04 3.01E-03 10 53 "ASPH,CSNK1E,USP6NL,ERBB2,MYBPC1,SLC25A36,MYH14,KIAA0895L,SARS,SEMA6D" MicroRNA hsa-miR-7152-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-04 1.00E+00 3.34E-04 3.08E-03 8 35 "TMEM184B,IP6K1,RPS6KL1,FEM1B,ZNF461,SEPT4,THRA,PIANP" MicroRNA hsa-miR-4694-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-04 1.00E+00 3.34E-04 3.08E-03 8 35 "MARCH4,LDHD,DNAJB6,ABI2,C8orf37,RTN3,PALLD,POGZ" MicroRNA hsa-miR-4520-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.93E-04 1.00E+00 3.34E-04 3.08E-03 8 35 "TTYH1,ABAT,CALN1,EN2,RNF165,ZIC5,RAB5B,MYO18A" MicroRNA hsa-miR-4312:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "CREM,CRCP,ADAMTS8,MAPT,P2RX7,GPR137C,ZNF426,HSPA4L,ZFP1,GPRIN3,VLDLR" MicroRNA hsa-miR-4760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "CDK13,FCF1,RAB40B,RBPJ,KCNK2,SH3TC2,ZYG11B,NAXD,SOX11,USP22,ZNF74" MicroRNA hsa-miR-6866-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "WDR35,ARHGDIA,BCL2L2,MTMR3,MAP7,STOML1,HSPA12B,CRCP,GPT2,UHRF1BP1L,TUBB2A" MicroRNA hsa-miR-5585-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "JAZF1,CCNT1,BAG4,DBN1,F5,MIER3,STMN1,MTR,PDE3A,OLA1,HECW1" MicroRNA hsa-miR-606:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "SDE2,USP37,EPS8,LAMP2,SMAD9,SESN3,PIGG,MYCBP2,SYT11,TMEM178B,WNK1" MicroRNA hsa-miR-8061:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "CDK13,FCF1,RAB40B,RBPJ,KCNK2,SH3TC2,ZYG11B,NAXD,SOX11,USP22,ZNF74" MicroRNA hsa-miR-219a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.95E-04 1.00E+00 3.35E-04 3.09E-03 11 63 "TPP1,DCC,BLOC1S6,G3BP2,WAC,KIAA1109,HSP90AA1,SESN3,PEX26,PEG10,ZMAT3" MicroRNA hsa-miR-4261:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-04 1.00E+00 3.41E-04 3.14E-03 13 84 "ELFN2,G3BP2,SEZ6,WAC,CELF1,TVP23A,PDPK1,NCBP3,LIMCH1,TMPO,NDRG4,HNRNPA3,SPATA13" MicroRNA hsa-miR-4446-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-04 1.00E+00 3.41E-04 3.14E-03 13 84 "FOXK1,CABP7,DRP2,AMOTL2,CELF1,PRRC2B,KCNH2,MAP4,PLCD1,PTPA,NLGN1,PEX26,NFASC" MicroRNA hsa-miR-1271-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-04 1.00E+00 3.41E-04 3.14E-03 13 84 "SLC25A25,PITPNM3,TUBD1,GABRB1,ATP8A2,MALT1,TNRC6A,NPTX1,PFKFB3,ANKRD36,SIN3B,RPL7L1,EVI5" MicroRNA hsa-miR-550a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-04 1.00E+00 3.43E-04 3.16E-03 14 95 "CLK4,STX16,CBS,YTHDC1,DYRK1A,HSPA12B,KCNJ11,CPEB4,SOX11,UNC5B,TMEM151B,ZNF70,ZNF154,WNK1" MicroRNA hsa-miR-1266-5p:Functional MTI Functional MTI miRTarbase 3.02E-04 1.00E+00 3.43E-04 3.16E-03 14 95 "ARID1A,MAP7,NCOR2,YTHDC1,SV2B,GABRA5,GPR75,PCSK2,KCTD15,PLEC,SMARCE1,DDN,CAMSAP2,PSD3" MicroRNA hsa-miR-6082:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-04 1.00E+00 3.43E-04 3.16E-03 5 13 "ARHGAP32,DCTN4,PFKP,ZFP30,BTBD3" MicroRNA hsa-miR-29c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.02E-04 1.00E+00 3.43E-04 3.16E-03 5 13 "BTF3L4,PPP2R5C,CPEB4,GSE1,USP22" MicroRNA hsa-miR-5579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-04 1.00E+00 3.46E-04 3.18E-03 9 44 "FMNL3,NUMBL,TMEM170A,FAM98B,PURG,RAB5B,ATF7IP,PRRC2C,JMJD1C" MicroRNA hsa-miR-875-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-04 1.00E+00 3.46E-04 3.18E-03 9 44 "BTF3L4,TOGARAM2,ELMSAN1,EGFR,MALT1,MYBPC1,OXR1,ITPRID2,SLC44A1" MicroRNA "GTAGGCA,MIR-189:MSigDB" "GTAGGCA,MIR-189:MSigDB" MSigDB 3.06E-04 1.00E+00 3.47E-04 3.20E-03 7 27 "SLITRK1,ARHGEF2,GPHN,PPP2R5C,BTBD3,SRPK2,KCNAB1" MicroRNA hsa-miR-300:Functional MTI Functional MTI miRTarbase 3.08E-04 1.00E+00 3.50E-04 3.22E-03 16 118 "SPAG9,MYOM2,COPB2,SEMA4D,BRPF3,ZNF181,ZNF546,MBNL1,MID1,SLC36A4,PRKCB,OCIAD1,CNKSR2,RUFY2,SLC6A8,WNK1" MicroRNA hsa-miR-6516-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.38E-04 1.00E+00 3.84E-04 3.53E-03 13 85 "ABCF1,ATP1B3,BACH1,CACNA1A,TOGARAM2,NRG2,TENM1,C8orf37,MED12L,SESN3,MYBPC1,GPR137C,MKRN3" MicroRNA hsa-miR-514b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-04 1.00E+00 3.86E-04 3.55E-03 11 64 "ZNF582,ABCC9,FEM1B,ANKMY1,TMEM151A,KCNB1,MDM4,ROBO2,CBX5,TLL2,NR2E1" MicroRNA hsa-miR-6790-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-04 1.00E+00 3.86E-04 3.55E-03 11 64 "DNAH17,FOXN3,TMEM184B,LONRF1,KATNAL1,PLEC,CAMSAP2,MGRN1,NSD1,TPM4,LRTM2" MicroRNA hsa-miR-1225-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-04 1.00E+00 4.09E-04 3.77E-03 8 36 "ASPH,CDR1,ZFYVE9,SEMA4D,ZNF678,SEMA6D,SON,DHX33" MicroRNA hsa-miR-6831-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-04 1.00E+00 4.09E-04 3.77E-03 8 36 "NLGN4X,ZBTB10,SLC35G1,METTL21A,C12orf49,DDHD2,KAT6B,TPM1" MicroRNA hsa-miR-144-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-04 1.00E+00 4.09E-04 3.77E-03 8 36 "ADARB2,TAOK1,MDM4,PCSK2,TMEM200C,ACSBG1,SYNPO2,KCNAB1" MicroRNA hsa-miR-4633-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-04 1.00E+00 4.09E-04 3.77E-03 8 36 "CFL2,RAB3C,MRNIP,KCNJ10,BEST3,CCSER2,PIGG,CPEB4" MicroRNA hsa-miR-1231:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.63E-04 1.00E+00 4.12E-04 3.79E-03 9 45 "CACNA1A,FOXF2,POLL,THYN1,PTPA,AMBRA1,RUFY2,FAIM2,SOX5" MicroRNA hsa-miR-4675:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.69E-04 1.00E+00 4.19E-04 3.86E-03 12 75 "FOXK1,PHF19,DBN1,ABCC5,CELF1,KBTBD12,PKM,PTPA,PRRT2,SBF1,PEX26,THRA" MicroRNA hsa-miR-4424:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.69E-04 1.00E+00 4.19E-04 3.86E-03 12 75 "HACE1,SLC7A14,STARD3NL,HMGB1,SLC35G1,MYBPC1,GRAMD1C,SLC30A10,FAM126B,TRPS1,RPL7L1,USP1" MicroRNA hsa-miR-1273a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.80E-04 1.00E+00 4.30E-04 3.96E-03 13 86 "NRXN3,PLEKHM1,ANKFY1,FUT9,KCNN3,CHST6,ZSCAN2,ALG9,FNBP1,GANAB,ARL10,PPIL6,UBC" MicroRNA hsa-miR-7159-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.80E-04 1.00E+00 4.30E-04 3.96E-03 13 86 "KIAA0319,DDX46,GABRB1,GABRG2,TRAPPC13,SALL1,MYO18A,KIF13A,ERBIN,CAMSAP2,KIAA0930,TRPC3,CERS6" MicroRNA hsa-miR-6774-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-04 1.00E+00 4.40E-04 4.05E-03 4 8 "CCPG1,MRO,DCTN4,KDM2B" MicroRNA hsa-miR-1273:PITA hsa-miR-1273:PITA_TOP PITA 3.90E-04 1.00E+00 4.41E-04 4.07E-03 7 28 "AXIN2,CNIH2,EVI5L,ARHGEF6,ABCC5,PAN3,CPNE4" MicroRNA hsa-miR-514a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.90E-04 1.00E+00 4.42E-04 4.07E-03 11 65 "ZNF582,ABCC9,FEM1B,ANKMY1,TMEM151A,KCNB1,MDM4,ROBO2,CBX5,TLL2,NR2E1" MicroRNA hsa-miR-200b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.92E-04 1.00E+00 4.44E-04 4.09E-03 10 55 "PROM1,CPS1,CS,MDM4,OLA1,ZMAT4,CLIP1,HHIP,ZNF138,PMEPA1" MicroRNA hsa-miR-4264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-04 1.00E+00 4.73E-04 4.36E-03 14 98 "PHF12,USP37,ZNF583,COL4A5,GABRG1,KCNK10,PKN2,FITM2,ZNF844,RAP1GDS1,CXXC4,KIF21B,ZNF24,ZNF195" MicroRNA hsa-miR-1193:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.18E-04 1.00E+00 4.73E-04 4.36E-03 14 98 "ABCF1,XKR4,DIRAS1,CRY2,TOMM20,BLOC1S6,ABI2,MRPL10,MAP2,ZSCAN2,CHD9,WDTC1,POGZ,MSRB3" MicroRNA hsa-miR-6724-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 4.88E-04 4.49E-03 9 46 "FOXK1,SUMF2,ELAVL3,ADAMTS13,ZDHHC15,ZDHHC8,ZYG11B,ZKSCAN3,SP2" MicroRNA hsa-miR-6773-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 4.88E-04 4.49E-03 9 46 "FOXK1,SUMF2,ELAVL3,ADAMTS13,ZDHHC15,ZDHHC8,ZYG11B,ZKSCAN3,SP2" MicroRNA hsa-miR-3913-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 4.88E-04 4.49E-03 9 46 "PLEKHG5,SEMA4G,ARRB1,FEM1B,FRY,NCKAP1,ADAM28,FICD,CADM2" MicroRNA hsa-miR-3158-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 4.88E-04 4.49E-03 9 46 "BCL7A,CABP7,THSD7A,CHST15,AMOTL2,GDAP1L1,MRPS18A,NLGN1,NFASC" MicroRNA hsa-miR-4474-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.31E-04 1.00E+00 4.88E-04 4.49E-03 9 46 "SLC24A2,PHF14,FRY,CEP85L,DDR2,GPSM2,ITPRID2,KLHL7,SIRT1" MicroRNA hsa-miR-3927-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.40E-04 1.00E+00 4.97E-04 4.58E-03 8 37 "SEMA7A,LONRF2,FOXO3,HSF2,LIFR,SESN3,RICTOR,ZNF708" MicroRNA hsa-miR-1307:mirSVR_highEffct hsa-miR-1307:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.40E-04 1.00E+00 4.97E-04 4.58E-03 8 37 "RBM10,ZNF385A,EIF1,GLI2,CLASRP,TAGLN3,ACER3,SIN3B" MicroRNA hsa-miR-590-5p:Functional MTI Functional MTI miRTarbase 4.47E-04 1.00E+00 5.05E-04 4.65E-03 11 66 "CREB5,TMEM170A,FGF12,FOXO3,CHL1,ZNF678,MBNL1,OLR1,PURG,KANSL3,ATF7IP" MicroRNA hsa-miR-4712-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-04 1.00E+00 5.05E-04 4.65E-03 11 66 "CS,RIMS3,GOLGA7,MDM4,ADAM22,ZNF426,ZNF667,ATP11A,DDHD1,ZNF23,ZNF138" MicroRNA hsa-miR-1285-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.47E-04 1.00E+00 5.05E-04 4.65E-03 11 66 "INTS2,RCAN1,ASB3,SEC23B,SHC3,TMLHE,AGTPBP1,OSBP2,MEAF6,CCDC14,ZDHHC20" MicroRNA hsa-miR-127-3p:PITA hsa-miR-127-3p:PITA_TOP PITA 4.50E-04 1.00E+00 5.08E-04 4.68E-03 5 14 "SEPT7,RIMS4,AGAP3,BCAS3,SCN8A" MicroRNA hsa-miR-675:PITA hsa-miR-675:PITA_TOP PITA 4.50E-04 1.00E+00 5.08E-04 4.68E-03 5 14 "MARK4,ZNF385A,DLG4,SLC29A4,SNX22" MicroRNA hsa-miR-4697-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "FABP7,SLC6A17,SESN3,MTRF1L,SH3TC2,NMNAT2,SPART,ITPRID2,PRRC2C,LAT2" MicroRNA hsa-miR-6719-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "CCNT1,PPP1R16B,RPS6KL1,HSPA12B,NCKAP1,LSAMP,CHIC1,TMEM200C,TMEM151B,CADM2" MicroRNA hsa-miR-7155-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "DYNLL1,ATM,BTRC,FOXK1,CRY2,MSANTD2,SHMT2,BTBD3,ZC3H4,ALG1" MicroRNA hsa-miR-6824-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "CLU,PNKD,SEZ6,ZNF461,PDE3A,PDE1B,FBXL16,THRA,SSBP2,WNK1" MicroRNA hsa-miR-3935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "BACH1,SRSF11,BAG4,AKAP12,BLOC1S6,TNRC6A,PCDH11X,NUDT21,ZNF678,CHD9" MicroRNA hsa-miR-3136-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "DYNLL1,ATM,BTRC,FOXK1,CRY2,MSANTD2,SHMT2,BTBD3,ZC3H4,ALG1" MicroRNA hsa-miR-96-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.56E-04 1.00E+00 5.14E-04 4.73E-03 10 56 "FMNL2,BACH1,TBPL1,NRG2,SYNCRIP,SMC2,ZNF678,OLA1,PGBD4,TNFRSF1B" MicroRNA hsa-miR-654-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.62E-04 1.00E+00 5.21E-04 4.80E-03 19 159 "PHF19,ELMSAN1,APH1A,ANKFY1,CRCP,GLI2,METTL21A,FXYD6,ZC3H12B,NFIX,GPR173,FXYD1,FOXRED2,SLIT1,SPART,CLASP1,CRTC1,RICTOR,ITM2C" MicroRNA hsa-miR-100-5p:Functional MTI Functional MTI miRTarbase 4.69E-04 1.00E+00 5.29E-04 4.87E-03 26 251 "ATM,ATP1A2,ATP1B3,ATP2A2,QKI,NCOR2,YTHDC1,HS3ST2,MED12,FARSB,FGFR3,UBE2E3,FLT1,CAMKK2,HMGB1,MAP4,MKLN1,NFIA,RPL15,ATAT1,KANK1,PRRC2C,DCBLD1,RPL7L1,USP1,NLRP3" MicroRNA hsa-miR-6856-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.73E-04 1.00E+00 5.33E-04 4.91E-03 12 77 "TAOK1,ALDH4A1,LONRF2,AMOTL2,CACFD1,SESN3,NPTX2,NRGN,KCNK10,TNPO2,SYT5,RGMB" MicroRNA hsa-miR-564:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.86E-04 1.00E+00 5.47E-04 5.04E-03 15 111 "XKR4,APAF1,FMNL3,LONRF2,APPL1,SLC43A2,GPR75,GPR155,GPSM2,SMOX,STRN3,SLC1A2,ANKRD36,SSTR2,SS18" MicroRNA hsa-miR-6746-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.91E-04 1.00E+00 5.53E-04 5.10E-03 7 29 "KMT2C,LETMD1,METTL21A,LAMP2,DRAXIN,RADIL,PBLD" MicroRNA hsa-miR-187:PITA hsa-miR-187:PITA_TOP PITA 4.91E-04 1.00E+00 5.53E-04 5.10E-03 7 29 "NDRG3,LRFN1,HIPK3,PAN3,PPARGC1A,MAPK8IP3,FLRT2" MicroRNA hsa-miR-3132:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.11E-04 1.00E+00 5.75E-04 5.30E-03 11 67 "PLEKHG5,TAOK1,APP,BTF3L4,MICAL2,UBXN2A,FEM1B,MDFI,TNPO2,AHCYL2,TPM3" MicroRNA hsa-miR-1280:mirSVR_highEffct hsa-miR-1280:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 5.28E-04 1.00E+00 5.94E-04 5.47E-03 10 57 "PKP4,FEZ2,CST3,GRM3,GRM7,INSYN1,RBPJ,CAMKV,ASRGL1,STAU1" MicroRNA hsa-miR-4509:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-04 1.00E+00 5.94E-04 5.47E-03 10 57 "SLC24A4,TNRC6C,SIRPA,FRY,SARAF,GCK,HMGB1,CLIP1,ZC3H13,TPM4" MicroRNA hsa-miR-6764-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.28E-04 1.00E+00 5.94E-04 5.47E-03 10 57 "CLU,PNKD,SEZ6,ZNF461,PDE3A,PDE1B,FBXL16,THRA,SSBP2,WNK1" MicroRNA hsa-miR-624-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.32E-04 1.00E+00 5.99E-04 5.52E-03 8 38 "BTRC,ADAM22,BEST3,PTPRG,FIGN,UBR7,RMI1,XKR7" MicroRNA hsa-miR-4706:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.33E-04 1.00E+00 5.99E-04 5.52E-03 13 89 "LTBP4,PDZD4,CACNA1A,DIRAS1,CLU,TMEM184B,BTF3L4,DISC1,NFIX,C12orf49,SBF1,PEX26,INKA2" MicroRNA hsa-miR-197-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-04 1.00E+00 6.54E-04 6.02E-03 11 68 "PLEKHG5,TAOK1,APP,BTF3L4,MICAL2,UBXN2A,FEM1B,MDFI,TNPO2,AHCYL2,TPM3" MicroRNA hsa-miR-659-3p:Functional MTI Functional MTI miRTarbase 5.82E-04 1.00E+00 6.54E-04 6.02E-03 11 68 "PCDHGB4,DYNLL1,STX16,MAP7,CD38,PHF19,GPR155,MSR1,RPL15,SH3BP2,KLHL7" MicroRNA hsa-miR-4797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-04 1.00E+00 6.54E-04 6.02E-03 11 68 "SLC7A14,ZNF583,COL4A5,LRIG1,GABRG1,PKN2,FITM2,RAP1GDS1,CXXC4,FGD4,ZNF24" MicroRNA hsa-miR-6868-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.82E-04 1.00E+00 6.54E-04 6.02E-03 11 68 "C6orf89,PDXK,CDC27,GOLGA7,NLE1,DPF2,COPZ1,SLC6A8,SLC8A3,MYH15,FAM182B" MicroRNA hsa-miR-4709-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.95E-04 1.00E+00 6.68E-04 6.15E-03 13 90 "TNRC6C,BTRC,ARHGAP22,KIAA0040,E2F6,WAC,IDH3B,KCNN3,PDPK1,RGR,FBXL16,TRIM16L,PARP11" MicroRNA hsa-miR-1229-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.09E-04 1.00E+00 6.84E-04 6.30E-03 10 58 "TAOK1,APP,CDR1,ZFYVE9,UBXN2A,FEM1B,ZNF678,MDFI,TNPO2,SON" MicroRNA hsa-miR-8069:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.09E-04 1.00E+00 6.84E-04 6.30E-03 10 58 "SDE2,ASPH,CANX,RAB3C,PPP1R16B,ABI2,EN2,GATM,DICER1,RICTOR" MicroRNA hsa-miR-4751:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.09E-04 1.00E+00 6.84E-04 6.30E-03 10 58 "CASKIN1,SCML2,ANKFY1,MDFI,KSR2,ELP2,CLSTN1,SLIT1,ZC3H4,TNS1" MicroRNA hsa-miR-4745-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-04 1.00E+00 6.88E-04 6.34E-03 7 30 "ARHGDIA,LETMD1,BRSK1,ADAMTS13,IBA57,SLC6A1,SEPT8" MicroRNA hsa-miR-1538:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.13E-04 1.00E+00 6.88E-04 6.34E-03 7 30 "ARHGDIA,LETMD1,BRSK1,ADAMTS13,IBA57,SLC6A1,SEPT8" MicroRNA hsa-miR-6503-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-04 1.00E+00 6.92E-04 6.38E-03 6 22 "RPS6KL1,CYP27C1,MAPT,PDPK1,ZMAT4,STUM" MicroRNA hsa-miR-4527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-04 1.00E+00 6.92E-04 6.38E-03 6 22 "RPS6KL1,CYP27C1,MAPT,PDPK1,ZMAT4,STUM" MicroRNA hsa-miR-601:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.17E-04 1.00E+00 6.92E-04 6.38E-03 6 22 "GRAMD1B,NFS1,KLHL3,NR1D2,ZNF585B,TROVE2" MicroRNA hsa-miR-625-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.40E-04 1.00E+00 7.18E-04 6.61E-03 8 39 "BAG4,FKTN,GUCY1A2,IGFBP1,FIGN,IGSF9B,PEG10,USP1" MicroRNA hsa-miR-203b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.40E-04 1.00E+00 7.18E-04 6.61E-03 8 39 "NLGN4X,KIF6,DST,SIRPA,ZC3H11A,RAB30,SH3TC2,CNKSR2" MicroRNA hsa-miR-6718-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.40E-04 1.00E+00 7.18E-04 6.61E-03 8 39 "NLGN4X,KIF6,DST,SIRPA,ZC3H11A,RAB30,SH3TC2,CNKSR2" MicroRNA hsa-miR-3142:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.40E-04 1.00E+00 7.18E-04 6.61E-03 8 39 "SLC24A2,IP6K1,NEU3,CSRNP3,ADAMTS17,CAMSAP2,DOCK9,ZNF74" MicroRNA hsa-miR-6869-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.48E-04 1.00E+00 7.25E-04 6.68E-03 5 15 "PDZD4,LETMD1,FKTN,NFIX,DRAXIN" MicroRNA hsa-miR-1249:PITA hsa-miR-1249:PITA_TOP PITA 6.48E-04 1.00E+00 7.25E-04 6.68E-03 5 15 "NRXN2,HNRNPK,MSI1,POU3F2,VAMP1" MicroRNA hsa-miR-566:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-04 1.00E+00 7.40E-04 6.82E-03 11 69 "SLC24A4,TXNDC16,DOCK11,RNF14,METTL21A,CHST6,MAPK8IP3,CBX5,LAT2,CFAP298,GAN" MicroRNA hsa-miR-6839-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.61E-04 1.00E+00 7.40E-04 6.82E-03 11 69 "LCORL,DCAF5,CSNK1E,DLC1,GPR155,NFYA,MTRF1L,CNNM2,NCDN,PARD3,LINC00632" MicroRNA hsa-miR-3917:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.71E-04 1.00E+00 7.51E-04 6.92E-03 4 9 "CDC27,GUCY1A2,ATOH8,WIPF1" MicroRNA hsa-miR-551a:mirSVR_highEffct hsa-miR-551a:mirSVR_conserved_highEffect-0.5 MicroRNA.org 6.75E-04 1.00E+00 7.55E-04 6.96E-03 12 80 "SLC25A14,RAB33A,LETMD1,NTRK2,SIDT1,PTK2,TMEM255A,NCBP3,NUBPL,PJA1,CRB2,JPH3" MicroRNA hsa-miR-6715a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.75E-04 1.00E+00 7.55E-04 6.96E-03 12 80 "SLC24A4,KIF6,CPNE5,ZBTB10,PTGDR2,KSR2,TRA2B,DNAJC9,TGFBR3,LRRC8A,TPM3,SF1" MicroRNA hsa-miR-4417:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-04 1.00E+00 7.83E-04 7.22E-03 10 59 "ARHGDIA,DIRAS1,NUMBL,PHF19,DNAL1,KBTBD12,POLL,KCNK3,SATB1,SHMT2" MicroRNA hsa-miR-508-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-04 1.00E+00 7.83E-04 7.22E-03 10 59 "PUM1,RGS17,F3,RAB30,RASSF8,MBNL1,MDM4,PCMT1,ROBO1,SATB2" MicroRNA hsa-miR-1244:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-04 1.00E+00 7.83E-04 7.22E-03 10 59 "TAOK1,CDH2,LIN54,DNAL1,TMEM35A,HSP90AA1,RDX,ATF7IP,TRIM2,ZFP37" MicroRNA hsa-miR-4711-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.01E-04 1.00E+00 7.83E-04 7.22E-03 10 59 "INSYN2B,SLC2A11,KIAA1549L,COL9A2,FCF1,ZNF274,USP47,SALL1,FNDC3A,DAAM2" MicroRNA hsa-miR-1181:mirSVR_lowEffct hsa-miR-1181:mirSVR_nonconserved_lowEffect-0.1-0.5 MicroRNA.org 7.36E-04 1.00E+00 8.22E-04 7.58E-03 13 92 "DGCR6,VSTM2A,MAP4K4,MAMLD1,SRRM1,ZBTB49,HPSE2,NEUROD2,SNTG1,ZDHHC8,PPP2R2C,SOX2,FIP1L1" MicroRNA hsa-miR-5699-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-04 1.00E+00 8.37E-04 7.71E-03 11 70 "PLEKHG5,YTHDC1,EIF4G1,ELAVL3,RASL10A,MDGA1,KCNK10,ZDHHC8,PPP3CB,KCNIP3,SLC8A3" MicroRNA hsa-miR-7151-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-04 1.00E+00 8.37E-04 7.71E-03 11 70 "BAG4,HS3ST5,GREB1,RCAN1,DYRK1A,TBR1,SLC6A17,RGR,MBD5,CLUAP1,DDHD1" MicroRNA hsa-miR-4680-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.49E-04 1.00E+00 8.37E-04 7.71E-03 11 70 "ERBB2,TLX1,NEGR1,LSAMP,N6AMT1,PDPK1,PEX2,TMEM100,FNBP1,TROVE2,PSD3" MicroRNA hsa-miR-3618:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.58E-04 1.00E+00 8.46E-04 7.80E-03 7 31 "ARID1A,PDE4DIP,PUM1,KLHL3,FREM1,FAM126B,DDHD1" MicroRNA hsa-miR-182-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-04 1.00E+00 8.54E-04 7.87E-03 8 40 "MYADM,STAMBP,SCIN,KCNJ10,FBXW7,ZC4H2,PSD3,HPS4" MicroRNA hsa-miR-1245b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-04 1.00E+00 8.54E-04 7.87E-03 8 40 "SLC24A2,IP6K1,NEU3,CSRNP3,ADAMTS17,CAMSAP2,DOCK9,ZNF74" MicroRNA hsa-miR-7978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-04 1.00E+00 8.54E-04 7.87E-03 8 40 "IGLON5,DNAJB6,EN2,ZC3H4,ARL10,C5orf64,KCNK12,CSDE1" MicroRNA hsa-miR-219b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.70E-04 1.00E+00 8.59E-04 7.91E-03 22 205 "APAF1,ATM,PTBP2,TPP1,SUMF2,KIAA0513,DNAL1,HP1BP3,RASA4,WAC,ZNF585B,ZNF589,NCKAP1,FAM107A,SESN3,MXI1,ZNF844,SNX22,PEG10,MCF2L2,SSBP2,PARP11" MicroRNA hsa-miR-146a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.77E-04 1.00E+00 8.67E-04 7.99E-03 15 116 "ADCY2,ERBB2,ZNF391,TLX1,ZNF678,P2RX7,PRKAB2,SH3TC2,SLC8A1,ZFP1,ZNF415,ITPRID2,ARL10,PLEKHH2,ZNF708" MicroRNA hsa-miR-187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.00E-04 1.00E+00 8.92E-04 8.22E-03 6 23 "CCPG1,CRMP1,HIPK3,MRO,MAD2L2,INPP5B" MicroRNA hsa-miR-6786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.00E-04 1.00E+00 8.92E-04 8.22E-03 6 23 "MICAL2,ABI2,MRNIP,GNAS,OPRL1,LRRC55" MicroRNA hsa-miR-2115-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.16E-04 1.00E+00 9.10E-04 8.38E-03 13 93 "ARRB2,ZNF445,FAM13A,FKTN,APOPT1,LILRA2,RFFL,ZNF496,SHISAL1,NCOA7,PSAT1,SGK1,NSD1" MicroRNA hsa-miR-3169:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-04 1.00E+00 9.11E-04 8.40E-03 9 50 "SPOP,ABCD2,LDB2,CREM,SCML2,NFIX,RAB5B,TMCC1,TCF7L2" MicroRNA hsa-miR-7153-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-04 1.00E+00 9.11E-04 8.40E-03 9 50 "FOXN3,KLHL3,CALN1,PCYOX1,RNPS1,MYBPC1,OPHN1,FGD4,ZDHHC20" MicroRNA hsa-miR-5187-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-04 1.00E+00 9.11E-04 8.40E-03 9 50 "ABCD2,ERBB2,TLX1,N6AMT1,PEX2,TMEM100,KIAA0895L,FNBP1,PSD3" MicroRNA hsa-miR-6775-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.18E-04 1.00E+00 9.11E-04 8.40E-03 9 50 "TMEM132B,ARHGEF2,CHRNB2,VWA5A,PFKFB3,IQSEC3,INKA2,GANAB,VANGL2" MicroRNA hsa-miR-6751-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.45E-04 1.00E+00 9.42E-04 8.68E-03 14 105 "ARHGDIA,CLU,DBT,DOT1L,GRIK2,NLE1,DIRAS2,HSD11B1L,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,MEAF6" MicroRNA hsa-miR-378g:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.46E-04 1.00E+00 9.42E-04 8.68E-03 12 82 "RIPOR2,RUSC2,UFM1,ITPKB,MYBPC1,PKM,PPP1R1A,BCAS3,STUM,BDP1,CLUAP1,ZNF154" MicroRNA hsa-miR-4479:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.03E-04 1.00E+00 1.01E-03 9.26E-03 5 16 "GPRIN1,SLC12A5,AQP6,CADM1,VGF" MicroRNA hsa-miR-5189-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.04E-04 1.00E+00 1.01E-03 9.27E-03 13 94 "KIF6,SLC2A11,NRXN3,TOGARAM2,PITPNM3,GREB1,KIAA0513,FLT1,KCNJ10,DDR2,ARL10,VLDLR,HPS4" MicroRNA hsa-miR-6800-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "KIAA1324,CCNT1,TMEM170A,ELMSAN1,RABGAP1L,EDN1,ZNF585B,DICER1" MicroRNA hsa-miR-626:Non-Functional MTI Non-Functional MTI miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "BSN,C1orf52,TENM1,KIAA1755,PTPA,RUFY2,FAM214B,ZMAT3" MicroRNA hsa-miR-6784-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "GPRIN1,PNMA8B,CPNE5,NKX6-2,TMEM179,NEUROD2,EPN1,TMEM63C" MicroRNA hsa-miR-6826-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "CLOCK,KPNA5,ZNF680,RAB5B,NSD2,CSDE1,PRDM10,HNRNPA3" MicroRNA hsa-miR-5002-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "ZFYVE9,QKI,PLXNA4,RCAN1,EMID1,KIF21B,FAM124A,WIPF1" MicroRNA hsa-miR-643:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.09E-04 1.00E+00 1.01E-03 9.31E-03 8 41 "BACH1,TBPL1,VCAN,ELAVL4,MPRIP,NACC2,VLDLR,SIGLEC10" MicroRNA hsa-miR-526a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-518d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-520c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-4484:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "APP,PTCH2,CACNA2D2,CLCN3,CDON,ZMYND11,P2RY1,SEPHS1,RBFOX2,CADM1" MicroRNA hsa-miR-519b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-518f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-519a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-519c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-523-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-138-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "AS3MT,FZD9,TAOK1,ZEB2,FEM1B,MRVI1,FREM1,FAM126B,TPM3,PAK5" MicroRNA hsa-miR-518e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.17E-04 1.00E+00 1.02E-03 9.38E-03 10 61 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-4759:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.28E-04 1.00E+00 1.03E-03 9.48E-03 7 32 "SPOP,ABCD2,CREM,KCNK1,RAB5B,TCF7L2,PSD3" MicroRNA hsa-miR-621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.28E-04 1.00E+00 1.03E-03 9.48E-03 7 32 "TRMT9B,TOGARAM2,FOXO3,MYOZ2,MIER3,PABPC1L2A,ACTR3B" MicroRNA hsa-miR-371a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.28E-04 1.00E+00 1.03E-03 9.48E-03 7 32 "ADD1,FLT1,TPK1,AFF1,ADAM22,ZC3H12B,UEVLD" MicroRNA hsa-miR-6881-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.28E-04 1.00E+00 1.03E-03 9.48E-03 7 32 "MICAL2,RNPS1,IBA57,KANSL1,ZFP30,AMBRA1,PEG10" MicroRNA hsa-miR-7161-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.49E-04 1.00E+00 1.05E-03 9.69E-03 9 51 "CANX,RABGAP1L,NUDT21,ATXN2L,MYH15,ITGB3BP,SLC44A1,CADM1,PMEPA1" MicroRNA hsa-miR-3135a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.49E-04 1.00E+00 1.05E-03 9.69E-03 9 51 "PLEKHG5,KIAA1324,DNAL1,DYRK1A,AGBL5,PCMT1,SETD5,SLC2A5,SLC8A1" MicroRNA hsa-miR-423-3p:PITA hsa-miR-423-3p:PITA_TOP PITA 1.02E-03 1.00E+00 1.13E-03 1.04E-02 6 24 "LYPD1,FRY,EPB41L4B,KCTD2,VLDLR,PDSS2" MicroRNA hsa-miR-3621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.02E-03 1.00E+00 1.13E-03 1.04E-02 6 24 "LTBP4,KCNK3,KCNN1,CAMK2N2,SEPT4,ADAMTS17" MicroRNA hsa-miR-522-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-03 1.00E+00 1.16E-03 1.07E-02 10 62 "TAOK1,CALM1,NCAN,MSANTD4,TJAP1,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-376c-3p:Functional MTI Functional MTI miRTarbase 1.05E-03 1.00E+00 1.16E-03 1.07E-02 12 84 "GOLGA7B,ANK1,ATM,DAPK1,PDPK1,CDK14,ATAT1,ANKRD36,SNCB,SP4,VLDLR,RTN4" MicroRNA hsa-miR-187-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-03 1.00E+00 1.16E-03 1.07E-02 12 84 "CANX,CDC27,DMPK,RNPS1,FICD,USP51,GPR85,SLC25A36,ZFP1,TMCC1,SLC19A3,CIAPIN1" MicroRNA hsa-miR-6892-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-03 1.00E+00 1.19E-03 1.10E-02 8 42 "NCKAP5,TAOK1,MYADM,TMCC1,FBXW11,TUBB2A,CADM1,DHX33" MicroRNA hsa-miR-5587-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-03 1.00E+00 1.19E-03 1.10E-02 8 42 "GPRIN1,ANK1,CPNE5,CACNA1E,FRMPD4,PHYHIP,MAP4,RPS6KA2" MicroRNA hsa-miR-553:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-03 1.00E+00 1.19E-03 1.10E-02 4 10 "DST,EMX2,TBC1D16,LSAMP" MicroRNA hsa-miR-600:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-03 1.00E+00 1.21E-03 1.12E-02 9 52 "TRMT9B,SORBS3,SYNCRIP,HLF,HSP90AA1,C2orf72,NEXMIF,P2RY1,GAN" MicroRNA hsa-miR-1268a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-03 1.00E+00 1.21E-03 1.12E-02 9 52 "CAMK2G,CDC25B,EVI5L,NDST3,FRMPD4,EPB41,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-609:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-03 1.00E+00 1.21E-03 1.12E-02 9 52 "ARID1A,FOXK1,ZNF385A,ZBED3,KCND3,MPP2,RAB5B,PRRT2,NACC2" MicroRNA hsa-miR-4327:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.10E-03 1.00E+00 1.22E-03 1.12E-02 13 96 "ASPA,PLAA,PLCXD3,TMEM170A,IRAK4,MTMR10,ZNF793,ROBO1,SLC30A10,NFASC,PPIL6,CADM1,USP1" MicroRNA hsa-miR-320c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-03 1.00E+00 1.24E-03 1.14E-02 14 108 "ADD1,SEMA7A,TNRC6C,C2CD2,SCRN1,SYNCRIP,SRCAP,RBPJ,SEC14L1,HSPA4L,TAL1,PCDHA2,ARL10,TPD52" MicroRNA hsa-miR-3679-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.31E-03 1.21E-02 10 63 "GAPVD1,SYNCRIP,KCNMB4,MAT2A,NUCB2,ZNF426,C1orf109,MRAS,HSPA4L,TPM1" MicroRNA hsa-miR-4658:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-03 1.00E+00 1.31E-03 1.21E-02 10 63 "DNAH17,FOXN3,TMEM184B,LONRF1,KATNAL1,PLEC,CAMSAP2,MGRN1,NSD1,LRTM2" MicroRNA hsa-miR-4741:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.20E-03 1.00E+00 1.33E-03 1.22E-02 11 74 "FOXK1,PHF19,ABCC5,CELF1,KBTBD12,PKM,PTPA,PRRT2,SBF1,PEX26,THRA" MicroRNA hsa-miR-4433b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-03 1.00E+00 1.34E-03 1.24E-02 13 97 "KIF6,CS,GRB10,PACSIN2,HMGB1,CHIC1,OLR1,PLEC,SEMA6D,FBXW11,USP22,CYB561A3,RPL7L1" MicroRNA hsa-miR-450a-5p:Functional MTI Functional MTI miRTarbase 1.23E-03 1.00E+00 1.35E-03 1.25E-02 5 17 "HNRNPK,GPR155,CEP97,FBXW11,WIPF2" MicroRNA hsa-miR-1908-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-03 1.00E+00 1.35E-03 1.25E-02 5 17 "DNAH17,FOXK1,EPB41,PLD5,SLC11A1" MicroRNA hsa-miR-4787-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-03 1.00E+00 1.35E-03 1.25E-02 5 17 "KIAA1614,PTCH2,FUBP1,PROX1,CRTC1" MicroRNA hsa-miR-3667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.26E-03 1.00E+00 1.39E-03 1.28E-02 9 53 "UBXN2A,ANKMY1,SLC11A2,ZNF844,KLHDC8A,ASAP3,SP4,CRTC1,TRPS1" MicroRNA hsa-miR-598-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.29E-03 1.00E+00 1.42E-03 1.31E-02 6 25 "CASP8AP2,TUBD1,SPIN1,TNPO2,BTBD3,ZFP91" MicroRNA hsa-miR-450b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-03 1.00E+00 1.43E-03 1.32E-02 12 86 "CLOCK,FUT10,GRIK2,STMN1,CHST6,GPR137C,MINDY2,GALNT10,LRRC55,FAM126B,STAU1,NSD1" MicroRNA hsa-miR-4522:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-03 1.00E+00 1.48E-03 1.36E-02 13 98 "ZNF555,COL9A2,GAPVD1,SGSM2,DCTN4,ZNF549,KATNAL1,WAC,ZNF678,CHST6,STK32A,PEG10,ADAMTS17" MicroRNA hsa-miR-885-5p:Functional MTI Functional MTI miRTarbase 1.34E-03 1.00E+00 1.48E-03 1.36E-02 10 64 "RUNX1T1,GREB1,CEP170,EIF4G2,C8orf37,HHIPL1,SHC3,NWD1,TBCEL,USP22" MicroRNA hsa-miR-532-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.34E-03 1.00E+00 1.48E-03 1.36E-02 10 64 "THSD7A,RAB3C,TENM4,MRNIP,NKD1,RBPJ,BEST3,CCSER2,PIGG,EPC1" MicroRNA hsa-miR-1182:Functional MTI Functional MTI miRTarbase 1.35E-03 1.00E+00 1.48E-03 1.37E-02 11 75 "ARID1A,TEX22,SEC14L5,KLHL3,RCAN1,ZNF546,RBBP6,FAM214B,BDP1,USP22,PRDM10" MicroRNA hsa-miR-378d:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-03 1.00E+00 1.50E-03 1.38E-02 7 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-378e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-03 1.00E+00 1.50E-03 1.38E-02 7 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-378f:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-03 1.00E+00 1.50E-03 1.38E-02 7 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-378h:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-03 1.00E+00 1.50E-03 1.38E-02 7 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-378i:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.36E-03 1.00E+00 1.50E-03 1.38E-02 7 34 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-6835-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.44E-03 1.00E+00 1.58E-03 1.46E-02 12 87 "DBT,DOT1L,GRIK2,NLE1,KANSL1,GALNT10,ZFP30,NMNAT2,UNC5B,CLASP1,ZFP91,TPM3" MicroRNA hsa-miR-200a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-03 1.00E+00 1.59E-03 1.47E-02 9 54 "CPS1,CS,MDM4,OLA1,ZMAT4,CLIP1,HHIP,ZNF138,PMEPA1" MicroRNA hsa-miR-4686:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-03 1.00E+00 1.59E-03 1.47E-02 9 54 "HDAC4,FER,GJB1,GRIK3,IRF8,MKLN1,MYCN,CEP97,VLDLR" MicroRNA hsa-miR-6806-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.45E-03 1.00E+00 1.59E-03 1.47E-02 9 54 "PNMA8B,ST3GAL5,KIAA1549L,UBXN2A,SESN1,NCAM2,SMOX,POLR2F,FNDC9" MicroRNA hsa-miR-4758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.52E-03 1.00E+00 1.67E-03 1.54E-02 10 65 "YTHDC1,ABCC5,EIF4G1,APC2,PDLIM5,MDGA1,KCNK10,ZDHHC8,PPP3CB,WIPF2" MicroRNA hsa-miR-6837-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.55E-03 1.00E+00 1.70E-03 1.57E-02 15 124 "MARCH4,C6orf89,BAIAP3,KLHL3,CELF1,NSG1,GJB1,GRK4,NFIX,RNH1,HES6,MAPKBP1,TMEM178B,TMEM151B,PCDHA6" MicroRNA hsa-miR-1288-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.59E-03 1.00E+00 1.75E-03 1.61E-02 12 88 "C1QTNF3,IGDCC4,DIRAS1,ISPD,UFM1,CAMKK2,GUCY1A2,ZNF713,MYO18A,NEK4,FAM208A,SPATA13" MicroRNA hsa-miR-3939:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-03 1.00E+00 1.78E-03 1.64E-02 4 11 "CRY2,INKA2,PRMT8,HPS4" MicroRNA hsa-miR-615-3p:TargetScan hsa-miR-615-3p TargetScan 1.62E-03 1.00E+00 1.78E-03 1.64E-02 4 11 "GBX2,MYLK2,MAPT,ARFGAP1" MicroRNA hsa-miR-378b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-03 1.00E+00 1.78E-03 1.64E-02 7 35 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,CAB39,CELF4" MicroRNA hsa-miR-6753-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.62E-03 1.00E+00 1.78E-03 1.64E-02 7 35 "KLHL3,RPS6KL1,CYP27C1,KSR2,PALM,PKIA,ZMAT4" MicroRNA hsa-miR-1199-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.63E-03 1.00E+00 1.79E-03 1.65E-02 5 18 "KIAA1614,DNAH17,FOXK1,ABCC5,SLC11A1" MicroRNA hsa-miR-184:TargetScan hsa-miR-184 TargetScan 1.63E-03 1.00E+00 1.79E-03 1.65E-02 5 18 "EPB41L5,ALDH4A1,NCOR2,DBNL,CRTC1" MicroRNA hsa-miR-4466:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-03 1.00E+00 1.82E-03 1.67E-02 9 55 "ESYT2,FOXK1,DIS3L,AKAP5,MICAL2,NUMA1,FITM2,INAVA,NMNAT2" MicroRNA hsa-miR-592:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-03 1.00E+00 1.82E-03 1.67E-02 9 55 "AKAP12,KIAA0513,FOXO3,SESN3,HS6ST3,BTBD3,NMNAT2,PRRC2C,WRN" MicroRNA hsa-miR-1291:Functional MTI Functional MTI miRTarbase 1.65E-03 1.00E+00 1.82E-03 1.67E-02 9 55 "TMEM132B,ARHGEF2,CHRNB2,VWA5A,PFKFB3,IQSEC3,INKA2,GANAB,VANGL2" MicroRNA hsa-miR-6740-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-03 1.00E+00 1.82E-03 1.67E-02 9 55 "DYNLL1,DLC1,ZMAT1,HBS1L,MALT1,GLI2,ATXN1,SLC6A8,NMNAT2" MicroRNA hsa-miR-610:Functional MTI Functional MTI miRTarbase 1.67E-03 1.00E+00 1.84E-03 1.69E-02 11 77 "BARD1,LONRF2,KMT2C,ABCC5,PLEKHO1,CRCP,KIF5C,ZFP30,PALLD,FNBP1,ZXDA" MicroRNA hsa-miR-4685-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.68E-03 1.00E+00 1.84E-03 1.69E-02 15 125 "MARCH4,C6orf89,BAIAP3,KLHL3,CELF1,NSG1,GJB1,GRK4,NFIX,RNH1,HES6,MAPKBP1,TMEM178B,TMEM151B,PCDHA6" MicroRNA hsa-miR-4652-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-03 1.00E+00 1.87E-03 1.73E-02 10 66 "TBPL1,SEPT9,WASF3,SESN1,TDRKH,TLX1,PKM,POLR2F,SON,USP22" MicroRNA hsa-miR-6767-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.71E-03 1.00E+00 1.88E-03 1.73E-02 8 45 "DNAL1,MPP2,HS6ST3,GPR173,STX1B,WDR37,RPL7L1,ELFN1" MicroRNA hsa-miR-422a:Non-Functional MTI Non-Functional MTI miRTarbase 1.71E-03 1.00E+00 1.88E-03 1.73E-02 8 45 "ESYT2,DPY19L3,MYRF,IGDCC3,HIPK3,FOXG1,CAB39,CELF4" MicroRNA hsa-miR-5190:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.75E-03 1.00E+00 1.92E-03 1.77E-02 12 89 "ABCD2,RCAN1,MRNIP,SESN3,SLC22A23,ERC1,SPART,MPRIP,VWC2,KIAA0930,ZNF154,WIPF2" MicroRNA hsa-miR-4283:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-03 1.00E+00 2.04E-03 1.88E-02 11 78 "AP1B1,ARHGDIA,PUM1,GJB1,GRID1,KCTD15,RAB5B,KIAA0895L,SBF1,SCN2B,SF1" MicroRNA hsa-miR-4429:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.86E-03 1.00E+00 2.04E-03 1.88E-02 11 78 "ADD1,SEMA7A,TNRC6C,C2CD2,SYNCRIP,SRCAP,RBPJ,HSPA4L,TAL1,ARL10,TPD52" MicroRNA hsa-miR-551b:mirSVR_highEffct hsa-miR-551b:mirSVR_conserved_highEffect-0.5 MicroRNA.org 1.86E-03 1.00E+00 2.04E-03 1.88E-02 11 78 "LETMD1,PHF19,NKX2-2,NTRK2,SIDT1,PTK2,TMEM255A,NCBP3,SPART,PJA1,CRB2" MicroRNA hsa-miR-3117-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-03 1.00E+00 2.06E-03 1.90E-02 9 56 "ADARB2,KIAA0408,C8orf37,SMC2,PLD5,KCNB1,STMN1,ZHX3,GAN" MicroRNA hsa-miR-4475:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-03 1.00E+00 2.06E-03 1.90E-02 9 56 "NCKAP5,TAOK1,ARHGEF2,RAPGEF1,ADAMTS8,FBXW11,TUBB2A,CADM1,UBTF" MicroRNA hsa-miR-3663-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-03 1.00E+00 2.06E-03 1.90E-02 9 56 "APBB2,DDR1,DIRAS1,DOT1L,JAKMIP3,KCTD15,SLC6A8,ZFP91,TUBB2A" MicroRNA hsa-miR-675-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.88E-03 1.00E+00 2.06E-03 1.90E-02 9 56 "SMAD1,NEUROD2,OPCML,GPR173,PLP1,PROX1,MGRN1,ZNF711,ZNF195" MicroRNA hsa-miR-619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.92E-03 1.00E+00 2.10E-03 1.93E-02 10 67 "CBFA2T2,LRWD1,CAB39,RBPJ,LIMS1,CDK19,PRRC2C,WBP2,SSBP2,ZNF154" MicroRNA hsa-miR-4681:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-03 1.00E+00 2.11E-03 1.94E-02 7 36 "CCAR2,FOXK1,NEURL4,PRRC2B,MRAS,YPEL4,IQCE" MicroRNA hsa-miR-6775-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.93E-03 1.00E+00 2.11E-03 1.94E-02 7 36 "AMH,PRX,BRSK2,RGS6,MICAL2,NEUROD2,MGAT5B" MicroRNA hsa-miR-4293:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.05E-03 1.00E+00 2.25E-03 2.07E-02 14 115 "DOCK11,MICAL2,ATP13A4,B4GALNT1,TDRKH,AGBL5,MMP17,CCSER2,RAB5B,NCBP3,ATXN2,TUBB2A,ZFAND5,AP3B2" MicroRNA hsa-miR-1469:mirSVR_highEffct hsa-miR-1469:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.12E-03 1.00E+00 2.31E-03 2.13E-02 5 19 "EIF1,DCLK2,IL11RA,GDPD2,FEZF2" MicroRNA hsa-miR-6727-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-03 1.00E+00 2.31E-03 2.13E-02 5 19 "AMH,PRX,BRSK2,RGS6,SEC16A" MicroRNA hsa-miR-1268:PITA hsa-miR-1268:PITA_TOP PITA 2.12E-03 1.00E+00 2.31E-03 2.13E-02 5 19 "SDE2,CAMK2G,SEMA3D,HRH3,ZNF827" MicroRNA hsa-miR-8074:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-03 1.00E+00 2.31E-03 2.13E-02 5 19 "BACH1,TNRC6A,KCTD15,PEX2,ARC" MicroRNA hsa-miR-4304:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-03 1.00E+00 2.31E-03 2.13E-02 5 19 "KIAA1614,LIFR,ATF7IP,AMZ1,URM1" MicroRNA hsa-miR-1271-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-03 1.00E+00 2.32E-03 2.14E-02 12 91 "CLK4,STX16,CBS,YTHDC1,DYRK1A,HSPA12B,KCNJ11,SOX11,UNC5B,TMEM151B,ZNF70,ZNF154" MicroRNA hsa-miR-550a-3-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.12E-03 1.00E+00 2.32E-03 2.14E-02 12 91 "CLK4,STX16,CBS,YTHDC1,DYRK1A,HSPA12B,KCNJ11,SOX11,UNC5B,TMEM151B,ZNF70,ZNF154" MicroRNA hsa-miR-4771:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-03 1.00E+00 2.33E-03 2.15E-02 9 57 "ARHGDIA,COL9A1,PHF19,ABCC5,RNFT2,CYP27C1,AFF1,XRRA1,VSNL1" MicroRNA hsa-miR-3620-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-03 1.00E+00 2.33E-03 2.15E-02 9 57 "IPCEF1,PHF19,KBTBD12,ZMAT1,NPTX1,PKM,DRAXIN,SLC6A8,TUBB2A" MicroRNA hsa-miR-1587:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-03 1.00E+00 2.33E-03 2.15E-02 9 57 "IPCEF1,PHF19,KBTBD12,ZMAT1,NPTX1,PKM,DRAXIN,SLC6A8,TUBB2A" MicroRNA hsa-miR-1255b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-03 1.00E+00 2.33E-03 2.15E-02 9 57 "PLEKHG5,LONRF2,DCC,RFFL,GRIK3,EFHB,VAMP1,EVI5,TMEM163" MicroRNA hsa-miR-4325:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.14E-03 1.00E+00 2.34E-03 2.15E-02 17 154 "SLC12A5,CDK5R1,JAZF1,CLOCK,MICAL2,MRO,DLC1,DBF4,AGBL5,PDE4D,ZFYVE21,TATDN3,MAPK8,FAM126B,TROVE2,PLCB1,HNRNPA3" MicroRNA hsa-miR-4749-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-03 1.00E+00 2.34E-03 2.16E-02 10 68 "FOXK1,MRO,DKK3,METTL21A,CYP27C1,VWA2,NACC2,RPRM,MGAT5B,DPYSL5" MicroRNA hsa-miR-6862-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.15E-03 1.00E+00 2.34E-03 2.16E-02 10 68 "FOXK1,IGDCC3,MICAL2,SPATA2,GRM1,PKM,SLC30A10,CRTC1,MGAT5B,ZNF70" MicroRNA hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 2.15E-03 1.00E+00 2.34E-03 2.16E-02 10 68 "ATM,COPB2,KIAA0040,SYNCRIP,STMN1,MAT2A,PPP2R5E,PXK,GTDC1,CCDC88A" MicroRNA hsa-miR-520g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.28E-03 1.00E+00 2.48E-03 2.29E-02 7 37 "CALM1,EIF4G2,MSANTD4,CECR2,TJAP1,C10orf105,VSNL1" MicroRNA hsa-miR-4728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-03 1.00E+00 2.49E-03 2.30E-02 8 47 "ARMC12,NFS1,BTF3L4,FERMT2,MMP17,FAM98B,AGTPBP1,TOM1L2" MicroRNA hsa-miR-6846-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-03 1.00E+00 2.49E-03 2.30E-02 8 47 "TTYH1,DNAJB5,SH2B1,MFAP3L,FAM120B,GPR26,NFIX,PDE3A" MicroRNA hsa-miR-6760-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-03 1.00E+00 2.49E-03 2.30E-02 11 80 "TMEM132B,ZIC4,FYN,GABRB1,MBNL1,NUMA1,MAP6D1,HSPA4L,AMACR,ZNF24,HPS4" MicroRNA "TCGATGG,MIR-213:MSigDB" "TCGATGG,MIR-213:MSigDB" MSigDB 2.31E-03 1.00E+00 2.51E-03 2.31E-02 3 6 "APP,GANAB,SATB2" MicroRNA "CGGTGTG,MIR-220:MSigDB" "CGGTGTG,MIR-220:MSigDB" MSigDB 2.31E-03 1.00E+00 2.51E-03 2.31E-02 3 6 "SPTBN4,LHX2,NSD2" MicroRNA hsa-miR-652-3p:TargetScan hsa-miR-652-3p TargetScan 2.33E-03 1.00E+00 2.54E-03 2.34E-02 4 12 "NPTN,KCNB1,KCNN3,PRRX1" MicroRNA hsa-miR-4253:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-03 1.00E+00 2.61E-03 2.41E-02 10 69 "FOXK1,IGDCC3,MICAL2,SPATA2,GRM1,PKM,SLC30A10,CRTC1,MGAT5B,ZNF70" MicroRNA hsa-miR-6882-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-03 1.00E+00 2.61E-03 2.41E-02 10 69 "CALM1,USP6NL,FAM107B,SH3GLB1,FOXO3,CHIC1,CLDN11,EXD2,TUBB2A,ZXDA" MicroRNA hsa-miR-4744:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-03 1.00E+00 2.61E-03 2.41E-02 10 69 "SIRPA,FRY,SARAF,GCK,HMGB1,AFF1,GPR137C,ZNF827,ZC3H13,TPM4" MicroRNA hsa-miR-6080:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.40E-03 1.00E+00 2.62E-03 2.41E-02 6 28 "RNF157,MSANTD4,ADAM22,PDE4D,TROVE2,TMEM198" MicroRNA hsa-miR-5689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-03 1.00E+00 2.63E-03 2.43E-02 9 58 "CADM3,ISPD,QKI,SOCS5,SLC12A6,DNAJB6,P2RY1,OLA1,STX1B" MicroRNA hsa-miR-943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.42E-03 1.00E+00 2.63E-03 2.43E-02 9 58 "FEZ2,DBN1,FGF1,ZDHHC15,DDR2,ST8SIA5,SULF2,DAAM2,CADM2" MicroRNA hsa-miR-4276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.55E-03 1.00E+00 2.78E-03 2.56E-02 12 93 "ABCD2,IP6K1,RCAN1,TNRC6A,SESN3,NPTX1,SLC22A23,BTBD3,CDK19,SPART,WIPF2,FXR1" MicroRNA hsa-miR-425-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.85E-03 2.63E-02 8 48 "FOXK1,MTHFD2,PPARGC1A,GNAS,FAM208A,ATMIN,ZNF28,TFIP11" MicroRNA hsa-miR-1268b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.85E-03 2.63E-02 8 48 "CDC25B,EVI5L,NDST3,FRMPD4,EPB41,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-136-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.85E-03 2.63E-02 8 48 "CANX,COPS4,GABRA4,TTLL7,SOX5,SOX11,TGFBR3,PARP11" MicroRNA hsa-miR-6735-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.85E-03 2.63E-02 8 48 "MTHFD2,GBX2,RAB30,TNRC6A,ZNF638,GNAL,FICD,SMOC1" MicroRNA hsa-miR-6874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.62E-03 1.00E+00 2.85E-03 2.63E-02 8 48 "COL9A2,BOC,SH3GLB1,APC2,NPTX2,PEG10,NSD1,NACC2" MicroRNA "CTCTATG,MIR-368:MSigDB" "CTCTATG,MIR-368:MSigDB" MSigDB 2.67E-03 1.00E+00 2.90E-03 2.67E-02 7 38 "CACNA1G,CAPN3,SEPT7,DLX1,MEF2C,RGS4,SATB2" MicroRNA hsa-miR-4750-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-03 1.00E+00 2.90E-03 2.67E-02 7 38 "ARID1A,RGS11,DNAJB5,GPER1,KCNN1,SYTL4,KIF1B" MicroRNA hsa-miR-1539:mirSVR_highEffct hsa-miR-1539:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 2.67E-03 1.00E+00 2.90E-03 2.68E-02 10 70 "MARK4,DLX1,FCGR3A,DKK3,CHL1,STMN2,PACSIN2,KLC1,TNR,NPDC1" MicroRNA hsa-miR-1266-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-03 1.00E+00 2.90E-03 2.68E-02 10 70 "GPR158,CCNT1,LRRFIP1,BAG4,RCAN1,DLC1,KIAA1958,SLC2A5,VAMP1,EXOC7" MicroRNA hsa-miR-1185-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-03 1.00E+00 2.90E-03 2.68E-02 10 70 "GAPVD1,SYNCRIP,KCNMB4,MAT2A,NUCB2,ZNF426,C1orf109,MRAS,HSPA4L,TPM1" MicroRNA hsa-miR-3144-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.67E-03 1.00E+00 2.90E-03 2.68E-02 10 70 "GPRIN1,TRMT9B,TBPL1,SEPT9,SESN1,TLX1,CELF5,NFIX,PKM,POLR2F" MicroRNA hsa-miR-566:PITA hsa-miR-566:PITA_TOP PITA 2.71E-03 1.00E+00 2.94E-03 2.71E-02 5 20 "CABP1,EEF1A2,EIF1,GABRB3,SMG6" MicroRNA hsa-miR-4499:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.79E-03 1.00E+00 3.03E-03 2.79E-02 11 82 "ZC3H11A,ZBED3,SESN1,GRM3,CIT,NUCB1,ATP8B4,SEPT8,VSNL1,WNK3,FXR1" MicroRNA hsa-miR-4492:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-03 1.00E+00 3.07E-03 2.83E-02 14 119 "FOXK1,RGS6,PHF19,ANKRD13B,KBTBD12,PRRC2B,KCNH2,NFIX,PKM,PTPA,KIAA0895L,PEX26,INTS3,TMEM63C" MicroRNA hsa-miR-5001-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-03 1.00E+00 3.07E-03 2.83E-02 14 119 "FOXK1,RGS6,PHF19,ANKRD13B,KBTBD12,PRRC2B,KCNH2,NFIX,PKM,PTPA,KIAA0895L,PEX26,INTS3,TMEM63C" MicroRNA hsa-miR-4498:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-03 1.00E+00 3.07E-03 2.83E-02 14 119 "FOXK1,RGS6,PHF19,ANKRD13B,KBTBD12,PRRC2B,KCNH2,NFIX,PKM,PTPA,KIAA0895L,PEX26,INTS3,TMEM63C" MicroRNA hsa-miR-4726-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.83E-03 1.00E+00 3.07E-03 2.83E-02 14 119 "GRAMD1B,PHYHIP,ZNF585B,CELF3,TJAP1,ZYG11B,ATXN2,HSPA4L,SH3BP2,SLIT1,UBTF,KLC2,ZNF154,ITM2C" MicroRNA hsa-miR-18b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.90E-03 1.00E+00 3.15E-03 2.90E-02 6 29 "TEX22,SLC24A4,GPD1,XRRA1,ZMAT3,WBP2" MicroRNA hsa-miR-622:Functional MTI Functional MTI miRTarbase 2.97E-03 1.00E+00 3.22E-03 2.96E-02 13 107 "BEND6,ZNF578,TENM4,DISC1,KCNN3,SESN3,NCR3LG1,ZNF844,SALL1,SCP2,UNC5B,KLHL7,ZNF195" MicroRNA hsa-miR-4274:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-03 1.00E+00 3.25E-03 2.99E-02 8 49 "CASK,BAG4,NCOR2,SOCS5,GNAS,ZC3H14,ATXN2,ANKRD36" MicroRNA hsa-miR-1178-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-03 1.00E+00 3.25E-03 2.99E-02 8 49 "ZNF578,ARHGAP22,OGG1,PACSIN1,PEG10,CLDND1,DPYSL5,PRDM10" MicroRNA hsa-miR-28-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.00E-03 1.00E+00 3.25E-03 2.99E-02 8 49 "INTS2,PHF12,EIF4G2,ZFYVE21,UHRF1BP1,DRAXIN,COPZ1,TRPS1" MicroRNA hsa-miR-4640-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.06E-03 1.00E+00 3.31E-03 3.05E-02 14 120 "GRAMD1B,PHYHIP,ZNF585B,CELF3,TJAP1,ZYG11B,ATXN2,HSPA4L,SH3BP2,SLIT1,UBTF,KLC2,ZNF154,ITM2C" MicroRNA hsa-miR-556-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-03 1.00E+00 3.32E-03 3.06E-02 9 60 "SLC24A4,TRMT9B,PITPNM3,MTX3,ZBTB49,TROVE2,DDHD1,STXBP4,PHTF2" MicroRNA hsa-miR-7153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-03 1.00E+00 3.32E-03 3.06E-02 11 83 "PLEKHG5,NSL1,MICAL2,MRPL10,GPM6B,MPP2,KCTD15,ELP2,RUFY2,TMEM136,TMPRSS5" MicroRNA hsa-miR-4255:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-03 1.00E+00 3.32E-03 3.06E-02 11 83 "CDC14B,ZNF555,CLTA,CNN3,CPS1,SOCS5,SUCO,RAB30,FICD,MTCH1,NSD2" MicroRNA hsa-miR-4749-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.07E-03 1.00E+00 3.32E-03 3.06E-02 11 83 "LTBP4,PDZD4,CACNA1A,CLU,TMEM184B,DISC1,NFIX,C12orf49,SBF1,PEX26,INKA2" MicroRNA hsa-miR-6876-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.11E-03 1.00E+00 3.37E-03 3.10E-02 7 39 "BSN,C1orf52,TENM1,KIAA1755,PTPA,RUFY2,FAM214B" MicroRNA hsa-miR-517c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-03 1.00E+00 3.50E-03 3.22E-02 4 13 "DBN1,PTK2B,NACC2,USP1" MicroRNA hsa-miR-517a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-03 1.00E+00 3.50E-03 3.22E-02 4 13 "DBN1,PTK2B,NACC2,USP1" MicroRNA hsa-miR-6070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.24E-03 1.00E+00 3.50E-03 3.22E-02 4 13 "SORCS2,EN2,EXOSC10,ALG9" MicroRNA hsa-miR-548ao-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.40E-03 1.00E+00 3.68E-03 3.39E-02 5 21 "FICD,PPP2R5C,ZNF844,ASAP3,GAN" MicroRNA "GTCAACC,MIR-380-5P:MSigDB" "GTCAACC,MIR-380-5P:MSigDB" MSigDB 3.40E-03 1.00E+00 3.68E-03 3.39E-02 5 21 "KLHL13,MICAL2,CREG2,MDGA2,TRIM2" MicroRNA hsa-miR-1292-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-03 1.00E+00 3.69E-03 3.40E-02 8 50 "ABI2,VPS26C,NRGN,PHKG1,KCTD15,PRKAB2,NFASC,TAB2" MicroRNA hsa-miR-4799-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-03 1.00E+00 3.69E-03 3.40E-02 8 50 "CACNA2D1,CDC27,GOLGA7,KCNJ11,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-4781-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-03 1.00E+00 3.69E-03 3.40E-02 8 50 "LTBP4,ATP2A2,CLU,CRMP1,BEST3,SNX22,UNC5B,WSCD1" MicroRNA hsa-miR-597-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.41E-03 1.00E+00 3.69E-03 3.40E-02 8 50 "ANK1,AKAP12,HS6ST3,EPDR1,BTBD3,NMNAT2,PRRC2C,WRN" MicroRNA hsa-miR-524-3p:PITA hsa-miR-524-3p:PITA_TOP PITA 3.47E-03 1.00E+00 3.75E-03 3.45E-02 6 30 "SRGAP3,EBF1,GRIN1,GPR88,DDN,CSDE1" MicroRNA hsa-miR-525-3p:PITA hsa-miR-525-3p:PITA_TOP PITA 3.47E-03 1.00E+00 3.75E-03 3.45E-02 6 30 "SRGAP3,EBF1,GRIN1,GPR88,DDN,CSDE1" MicroRNA hsa-miR-1282:PITA hsa-miR-1282:PITA_TOP PITA 3.47E-03 1.00E+00 3.75E-03 3.45E-02 6 30 "DDX3Y,MAML1,CHD9,UNC5B,TCF4,ZNF384" MicroRNA hsa-miR-708-3p:Functional MTI Functional MTI miRTarbase 3.61E-03 1.00E+00 3.89E-03 3.59E-02 7 40 "KCNJ10,PSAT1,COPZ1,SH3BP2,SEPT8,ASXL3,SGK3" MicroRNA hsa-miR-7975:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-03 1.00E+00 3.89E-03 3.59E-02 7 40 "RNF157,AMPD3,FREM1,KANSL1,SCN2B,GALNT10,ZNF34" MicroRNA hsa-miR-487b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-03 1.00E+00 3.89E-03 3.59E-02 7 40 "TMEM263,PROM1,USP6NL,EN2,ZDHHC22,SLC36A4,FIGN" MicroRNA hsa-miR-4669:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-03 1.00E+00 3.89E-03 3.59E-02 7 40 "MARCH4,FOXK1,EIF5,SESN3,PRRT2,NSD2,STOX2" MicroRNA hsa-miR-5195-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.61E-03 1.00E+00 3.89E-03 3.59E-02 7 40 "SRSF11,CREB5,DBN1,MIER3,MYO5A,ASTN2,SF1" MicroRNA hsa-miR-4802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.70E-03 1.00E+00 3.99E-03 3.68E-02 11 85 "CCNT1,TOGARAM2,MATR3,SEPT9,GRK4,ZBTB45,GPR137C,PURG,MINDY2,STX1B,ZFAND5" MicroRNA hsa-miR-762:Functional MTI Functional MTI miRTarbase 3.83E-03 1.00E+00 4.13E-03 3.80E-02 14 123 "FOXK1,RGS6,PHF19,ANKRD13B,KBTBD12,PRRC2B,KCNH2,NFIX,PKM,PTPA,KIAA0895L,PEX26,INTS3,TMEM63C" MicroRNA hsa-miR-4720-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-03 1.00E+00 4.17E-03 3.84E-02 8 51 "CACNA2D1,CDC27,GOLGA7,KCNJ11,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-5588-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.87E-03 1.00E+00 4.17E-03 3.84E-02 8 51 "CACNA2D1,CDC27,GOLGA7,KCNJ11,PDE3A,DPF2,SLC6A8,FAM182B" MicroRNA hsa-miR-6761-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.88E-03 1.00E+00 4.18E-03 3.85E-02 3 7 "VWA5A,NFIX,TPM1" MicroRNA hsa-miR-151a-5p:TargetScan hsa-miR-151a-5p TargetScan 3.88E-03 1.00E+00 4.18E-03 3.85E-02 3 7 "RALGAPA1,MTX3,IL1RAPL1" MicroRNA hsa-miR-7845-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.95E-03 1.00E+00 4.26E-03 3.92E-02 12 98 "ARHGEF2,TOGARAM2,EIF4G1,ERBB2,HBS1L,RAB30,AGFG1,GPR137C,SLC6A1,SLC37A2,NACC2,UBTF" MicroRNA hsa-miR-6508-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.04E-03 1.00E+00 4.35E-03 4.01E-02 10 74 "ZNF585B,TOMM40L,ZYG11B,ATXN2,SFPQ,HSPA4L,SLIT1,UBTF,KLC2,ZNF154" MicroRNA hsa-miR-937:mirSVR_highEffct hsa-miR-937:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.12E-03 1.00E+00 4.44E-03 4.09E-02 6 31 "DNM1L,SLC9B2,ZNF605,PPP3CB,ITSN1,ANO4" MicroRNA hsa-miR-3657:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-03 1.00E+00 4.48E-03 4.13E-02 7 41 "MARCH4,FOXK1,EIF5,SESN3,UBTF,NSD2,STOX2" MicroRNA hsa-miR-6834-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-03 1.00E+00 4.48E-03 4.13E-02 7 41 "PAX6,C11orf49,ARMH4,CLIP1,PRRC2C,WBP2,ZNF24" MicroRNA hsa-miR-490-5p:Functional MTI Functional MTI miRTarbase 4.17E-03 1.00E+00 4.48E-03 4.13E-02 7 41 "TAOK1,APP,GPR137C,CNNM2,FAM102A,FGD4,ZNF28" MicroRNA hsa-miR-1251-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.17E-03 1.00E+00 4.48E-03 4.13E-02 7 41 "MARCH4,CABP7,SIRPA,DCTN4,ATP13A4,SNRK,TMEM151B" MicroRNA hsa-miR-6743-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.22E-03 1.00E+00 4.54E-03 4.19E-02 5 22 "ADD1,PTBP2,ZNF638,PDYN,PTGR2" MicroRNA hsa-miR-299-5p:Functional MTI Functional MTI miRTarbase 4.29E-03 1.00E+00 4.61E-03 4.25E-02 9 63 "ZBTB10,STX16,PLXNC1,DCTN4,TCERG1,TNRC6A,NEUROD1,ROBO1,SPP1" MicroRNA hsa-miR-1825:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.30E-03 1.00E+00 4.62E-03 4.25E-02 12 99 "TRMT9B,MSANTD4,XRRA1,TMOD2,A2ML1,KCNIP2,SLC8A1,SNAP25,LHPP,INKA2,DDHD1,PLPP4" MicroRNA hsa-miR-542-5p:PITA hsa-miR-542-5p:PITA_TOP PITA 4.35E-03 1.00E+00 4.68E-03 4.31E-02 4 14 "DLG4,DPH1,TBR1,LRRC8A" MicroRNA hsa-miR-371-3p:PITA hsa-miR-371-3p:PITA_TOP PITA 4.35E-03 1.00E+00 4.68E-03 4.31E-02 4 14 "USP37,ZNF385A,ARX,MYT1L" MicroRNA hsa-miR-148b-5p:Functional MTI Functional MTI miRTarbase 4.38E-03 1.00E+00 4.70E-03 4.33E-02 8 52 "COL9A2,BOC,SH3GLB1,APC2,NPTX2,PEG10,NSD1,NACC2" MicroRNA hsa-miR-6751-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-03 1.00E+00 4.76E-03 4.39E-02 11 87 "RGS11,TOMM20,ABI2,CAMSAP1,CELF1,TDRKH,MUM1,NKD1,NFIX,NPTX2,ZXDA" MicroRNA hsa-miR-1538:mirSVR_highEffct hsa-miR-1538:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 4.43E-03 1.00E+00 4.76E-03 4.39E-02 11 87 "EPS15L1,LETMD1,SH2B1,DHRS4,NF1,FSD1,CEP97,ROBO3,TPCN2,MTMR14,RIMBP2" MicroRNA hsa-miR-1914-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.43E-03 1.00E+00 4.76E-03 4.39E-02 11 87 "BSN,CACNA1B,DBN1,FKTN,POLL,KCNJ11,AFF1,SH3KBP1,GLDN,CLSTN2,ZNF138" MicroRNA hsa-miR-2054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.45E-03 1.00E+00 4.78E-03 4.40E-02 10 75 "EIF1,TUBD1,NTNG2,OLR1,MAPK7,SATB1,NTNG1,TRPS1,ZNF138,CSDE1" MicroRNA hsa-miR-4687-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.77E-03 1.00E+00 5.12E-03 4.72E-02 9 64 "MTA3,ADGRB2,GAPVD1,MTHFD2,KCNH1,DDR2,ZCCHC24,AJAP1,TPM3" MicroRNA hsa-miR-6815-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.90E-03 1.00E+00 5.26E-03 4.84E-02 10 76 "C1QTNF1,TMEM170A,ANKFY1,MTRF1L,PLEKHB2,RAP1GDS1,SLC2A5,KIAA0930,WBP2,BCL2L13" MicroRNA hsa-miR-3912-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "ARHGDIA,BSN,MAGI2,CELF1,FUT10,SHC3,CSRNP3,NR2E1" MicroRNA hsa-miR-1180-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "ARID1A,RGS11,MRPL10,HMX1,XRRA1,STX1B,SZT2,CBX5" MicroRNA hsa-miR-638:Functional MTI Functional MTI miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "DACT3,STARD10,FUT10,MIER3,GPR137C,GALNT10,SOX2,SP2" MicroRNA hsa-miR-7114-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "ARID1A,RGS11,MRPL10,HMX1,XRRA1,STX1B,SZT2,CBX5" MicroRNA hsa-miR-6755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "PLEKHG5,ELFN2,ASPH,BTF3L4,GNAS,MDM4,SMOX,AHCYL2" MicroRNA hsa-miR-6839-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "NCKAP1L,PRRX1,SEPT4,TNPO2,MYO18A,ZNF621,SLC30A4,WIPF2" MicroRNA hsa-miR-378j:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "NCKAP1L,PRRX1,SEPT4,TNPO2,MYO18A,ZNF621,SLC30A4,WIPF2" MicroRNA hsa-miR-8083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.93E-03 1.00E+00 5.29E-03 4.87E-02 8 53 "SPOP,ABCD2,TRMT9B,CREM,GPR137C,RAB5B,TCF7L2,NR2C2" MicroRNA hsa-miR-624-3p:Functional MTI Functional MTI miRTarbase 5.05E-03 1.00E+00 5.41E-03 4.99E-02 12 101 "PCDH19,TXNDC16,APAF1,DMPK,IBA57,ZNF713,P2RY1,CCSER2,ALG9,SMOC1,NR2E1,CADM2" MicroRNA hsa-miR-5707:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.18E-03 1.00E+00 5.55E-03 5.11E-02 5 23 "PLEKHG5,NRXN3,ACBD5,MMP17,SH3TC2" MicroRNA hsa-miR-6757-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-03 1.00E+00 5.67E-03 5.23E-02 9 65 "TMEM184B,NCOR2,SPATA2,GOLGA7,ING4,FAM49B,NR3C1,ZNF491,PPARA" MicroRNA hsa-miR-4296:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.30E-03 1.00E+00 5.67E-03 5.23E-02 9 65 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-6865-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.38E-03 1.00E+00 5.76E-03 5.31E-02 10 77 "C1QTNF1,TMEM170A,ANKFY1,MTRF1L,PLEKHB2,RAP1GDS1,SLC2A5,KIAA0930,WBP2,BCL2L13" MicroRNA hsa-miR-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.54E-03 1.00E+00 5.93E-03 5.46E-02 8 54 "SEC14L5,LONRF1,C2CD2L,EGFR,SEPT4,DDHD2,TCF7L2,ZNF138" MicroRNA hsa-miR-5092:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-03 1.00E+00 6.09E-03 5.61E-02 6 33 "DCC,HEYL,GTF2IRD2,CHIC1,SMIM11A,OGG1" MicroRNA hsa-miR-5090:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-03 1.00E+00 6.09E-03 5.61E-02 6 33 "AMH,PRX,BRSK2,RGS6,MICAL2,NEUROD2" MicroRNA hsa-miR-1911-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.69E-03 1.00E+00 6.09E-03 5.61E-02 6 33 "SRARP,STAG2,BEST3,RPRD1A,SEMA6D,CLIP2" MicroRNA hsa-miR-4804-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.70E-03 1.00E+00 6.09E-03 5.61E-02 4 15 "LIFR,TNPO2,PTPA,LRRC8A" MicroRNA hsa-miR-5009-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.86E-03 1.00E+00 6.27E-03 5.77E-02 9 66 "ADD2,ST6GALNAC3,CIT,PTPRB,SH3TC2,RPL15,ST6GAL1,ZMAT3,RUNDC3B" MicroRNA hsa-miR-4322:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.86E-03 1.00E+00 6.27E-03 5.77E-02 9 66 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-4265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.86E-03 1.00E+00 6.27E-03 5.77E-02 9 66 "AMPD3,ARHGDIA,NUMBL,DNAL1,POLL,KCNK3,SDK2,SATB1,SHMT2" MicroRNA hsa-miR-1307:PITA hsa-miR-1307:PITA_TOP PITA 5.98E-03 1.00E+00 6.39E-03 5.89E-02 3 8 "ZNF385A,AGAP3,TNPO2" MicroRNA hsa-miR-3677-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-03 1.00E+00 6.39E-03 5.89E-02 3 8 "ARHGDIA,SEPT9,VAMP1" MicroRNA hsa-miR-4485-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.98E-03 1.00E+00 6.39E-03 5.89E-02 3 8 "GPR37L1,TDRKH,CLIP1" MicroRNA hsa-miR-4777-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.20E-03 1.00E+00 6.62E-03 6.10E-02 8 55 "TAOK1,CALM1,NCAN,SLC35G1,C10orf105,PCSK1,ATP11A,HPS4" MicroRNA hsa-miR-645:Functional MTI Functional MTI miRTarbase 6.23E-03 1.00E+00 6.65E-03 6.12E-02 7 44 "AFF2,FRMD5,PLD5,NFYA,DDR2,TTC13,TMEM178B" MicroRNA hsa-miR-4761-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.23E-03 1.00E+00 6.65E-03 6.12E-02 7 44 "OGT,DNM2,SH3GLB1,SESN3,SH3TC2,ZMAT4,SMUG1" MicroRNA hsa-miR-323b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.23E-03 1.00E+00 6.65E-03 6.12E-02 7 44 "SPAG9,CBS,TMEM184B,BTF3L4,COL9A2,CREB5,UHRF1BP1" MicroRNA hsa-miR-92a-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.24E-03 1.00E+00 6.66E-03 6.13E-02 11 91 "CREB5,IQGAP2,TJAP1,OPHN1,FBXW7,ZFP30,UNC5B,CBX5,DPYSL5,CIAPIN1,GAN" MicroRNA hsa-miR-4734:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.27E-03 1.00E+00 6.69E-03 6.16E-02 5 24 "CACNA1A,SCIN,NFIX,RXRA,INKA2" MicroRNA hsa-miR-523:mirSVR_highEffct hsa-miR-523:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 6.27E-03 1.00E+00 6.69E-03 6.16E-02 5 24 "CTNND2,TMEM107,URGCP,TJP1,SF1" MicroRNA hsa-miR-3184-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-03 1.00E+00 6.90E-03 6.36E-02 9 67 "SDE2,ZNF555,DBT,ZBED3,GATM,EXD2,APOM,SMUG1,ZNF24" MicroRNA hsa-miR-6845-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-03 1.00E+00 6.90E-03 6.36E-02 9 67 "GRAMD1B,SEMA7A,TOM1,DOT1L,TMEM179,TJAP1,NKX2-2,SH3BP2,DNMBP" MicroRNA hsa-miR-6762-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-03 1.00E+00 6.90E-03 6.36E-02 9 67 "GRAMD1B,SEMA7A,TOM1,DOT1L,TMEM179,TJAP1,NKX2-2,SH3BP2,DNMBP" MicroRNA hsa-miR-4699-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.47E-03 1.00E+00 6.90E-03 6.36E-02 9 67 "ASPH,G3BP2,MTX3,DRP2,RBM12,GRID1,PPARA,ATXN1,ZFP91" MicroRNA hsa-miR-7107-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.62E-03 1.00E+00 7.06E-03 6.50E-02 6 34 "KLHL3,RPS6KL1,CYP27C1,KSR2,PALM,ZMAT4" MicroRNA hsa-miR-495-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.77E-03 1.00E+00 7.22E-03 6.65E-02 11 92 "CSMD2,CALM1,RTTN,ACBD5,YAF2,CELF1,MTHFD2,GLUL,CCSER2,CARF,PLSCR4" MicroRNA hsa-miR-584-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.92E-03 1.00E+00 7.37E-03 6.79E-02 8 56 "ZNF582,THSD7A,SMG7,G3BP2,GSN,NOVA2,SETD5,SLC37A2" MicroRNA hsa-miR-3940-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.13E-03 1.00E+00 7.60E-03 7.00E-02 9 68 "LCORL,USP28,DCAF5,PITPNM3,DLC1,NFYA,CNNM2,ATXN2,LINC00632" MicroRNA hsa-miR-191-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.51E-03 1.00E+00 8.00E-03 7.37E-02 5 25 "DPY19L3,MTX3,HMGB1,SSTR2,RPL7L1" MicroRNA hsa-miR-4655-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.51E-03 1.00E+00 8.00E-03 7.37E-02 5 25 "HCN2,PLEKHM1,APOPT1,TMEM179,SLC11A2" MicroRNA hsa-miR-1273c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.51E-03 1.00E+00 8.00E-03 7.37E-02 5 25 "XKR4,NR1D2,GANAB,ARL10,NELFE" MicroRNA hsa-miR-4794:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.63E-03 1.00E+00 8.12E-03 7.48E-02 14 133 "ADAR,SMIM17,BACH1,LDHD,COL9A2,LETMD1,ZNF44,IBA57,PDE1B,NSD1,FBXL16,SSBP2,ZNF610,CFAP298" MicroRNA hsa-miR-664a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.63E-03 1.00E+00 8.12E-03 7.48E-02 14 133 "ADAR,SMIM17,BACH1,LDHD,COL9A2,LETMD1,ZNF44,IBA57,PDE1B,NSD1,FBXL16,SSBP2,ZNF610,CFAP298" MicroRNA hsa-miR-4281:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-03 1.00E+00 8.14E-03 7.50E-02 6 35 "IP6K1,ELAVL3,IBA57,KCNH2,PRRT2,NCDN" MicroRNA hsa-miR-6816-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-03 1.00E+00 8.14E-03 7.50E-02 6 35 "TEX22,DMPK,MAN2A2,NUMA1,POU3F2,WIPF2" MicroRNA hsa-miR-6850-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.65E-03 1.00E+00 8.14E-03 7.50E-02 6 35 "DMPK,EIF1,FUT9,ITPKB,LRRC4B,MDM4" MicroRNA hsa-miR-4700-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.68E-03 1.00E+00 8.17E-03 7.53E-02 10 81 "LDHD,KBTBD11,GTF2IRD2,TACC2,CAB39,KSR2,KANSL1,WNK1,RNF146,SPATA13" MicroRNA hsa-miR-6499-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.70E-03 1.00E+00 8.19E-03 7.54E-02 8 57 "PTCHD1,CASKIN1,TXNDC16,TRMT9B,CPLX1,BVES,MDM4,ZKSCAN3" MicroRNA hsa-miR-6789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-03 1.00E+00 8.34E-03 7.68E-02 9 69 "PNMA8B,DOCK11,BRSK2,ZMYM4,LETMD1,CHST6,NFIX,LAT2,GAN" MicroRNA hsa-miR-4764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.85E-03 1.00E+00 8.34E-03 7.68E-02 9 69 "FOXK1,DLGAP2,LRWD1,SEC24C,FGFR3,FAM49B,NR3C1,AGBL5,GPR137C" MicroRNA hsa-miR-585-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.97E-03 1.00E+00 8.47E-03 7.80E-02 7 46 "TXNDC16,FEM1B,SH3GLB1,GOLGA7,EIF4G2,PFKFB2,SMARCC2" MicroRNA hsa-miR-4316:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.97E-03 1.00E+00 8.47E-03 7.80E-02 12 107 "SLC24A4,TXNDC16,TRMT9B,ARHGDIA,BSCL2,KIF3A,OLR1,TTLL7,KCNIP3,WDTC1,CBX5,MEAF6" MicroRNA hsa-miR-1261:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.54E-03 1.00E+00 9.07E-03 8.36E-02 8 58 "DCAF5,LDHD,ZNF585B,PRKCB,RGR,FRYL,PARD3,C12orf4" MicroRNA hsa-miR-758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.54E-03 1.00E+00 9.07E-03 8.36E-02 8 58 "CHRDL1,TLR7,ZNF181,TJAP1,ATXN1,CNKSR2,TACC1,MEAF6" MicroRNA "GGATCCG,MIR-127:MSigDB" "GGATCCG,MIR-127:MSigDB" MSigDB 8.63E-03 1.00E+00 9.17E-03 8.45E-02 3 9 "SEPT7,RIMS4,BCAS3" MicroRNA hsa-let-7d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.63E-03 1.00E+00 9.17E-03 8.45E-02 3 9 "QKI,CELF1,PDE2A" MicroRNA hsa-miR-6502-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.80E-03 1.00E+00 9.34E-03 8.60E-02 6 36 "FRMD5,SHISA6,SNX10,VPS13A,ADAMTS17,GPRIN3" MicroRNA hsa-miR-1301-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.80E-03 1.00E+00 9.34E-03 8.60E-02 6 36 "FRMD5,SHISA6,SNX10,VPS13A,ADAMTS17,GPRIN3" MicroRNA hsa-miR-210-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.96E-03 1.00E+00 9.51E-03 8.76E-02 7 47 "XKR4,TRIM41,LONRF2,MRO,MSANTD4,SCN7A,NACC2" MicroRNA hsa-miR-7157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.96E-03 1.00E+00 9.51E-03 8.76E-02 7 47 "KBTBD11,CELF1,AP4S1,GLDN,SLIT1,TMEM151B,DICER1" MicroRNA hsa-miR-7158-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.96E-03 1.00E+00 9.51E-03 8.76E-02 7 47 "CFL2,UBXN2A,SUCO,MMP16,ZMAT3,PARD3,CSDE1" MicroRNA hsa-miR-1203:PITA hsa-miR-1203:PITA_TOP PITA 9.16E-03 1.00E+00 9.71E-03 8.95E-02 4 17 "PPFIA3,CAMK2N2,NFIX,SOX11" MicroRNA hsa-miR-887-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.16E-03 1.00E+00 9.71E-03 8.95E-02 4 17 "SPATA2,TDRKH,MDM4,BTBD7" MicroRNA hsa-miR-611:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.16E-03 1.00E+00 9.71E-03 8.95E-02 4 17 "BCL7A,TM9SF4,RFX2,ZNF74" MicroRNA hsa-miR-4656:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.43E-03 1.00E+00 9.99E-03 9.20E-02 9 71 "PHF19,FBXO25,DRP2,KBTBD12,PKM,RAB5B,PEX26,NFASC,PMEPA1" MicroRNA hsa-miR-4743-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.45E-03 1.00E+00 1.00E-02 9.23E-02 8 59 "LINC01551,PLCD1,SLC1A2,PEX26,ARC,USP22,CBX5,ZNF70" MicroRNA hsa-miR-3670:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-02 1.00E+00 1.06E-02 9.80E-02 7 48 "CDR1,SEC24C,PITPNM3,PPP1R16B,KIF21B,SEPT8,STXBP4" MicroRNA hsa-miR-4512:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-02 1.00E+00 1.06E-02 9.80E-02 7 48 "TXNDC16,APPL1,TOMM40L,ARHGAP12,ALG9,SFPQ,ANKRD24" MicroRNA hsa-miR-6737-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-02 1.00E+00 1.06E-02 9.80E-02 7 48 "KBTBD11,CELF1,AP4S1,GLDN,SLIT1,TMEM151B,DICER1" MicroRNA hsa-miR-1227-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-02 1.00E+00 1.06E-02 9.80E-02 7 48 "GRAMD1B,DNAJC6,TOM1,DOT1L,ELOVL5,NKX2-2,DNMBP" MicroRNA hsa-miR-5008-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.00E-02 1.00E+00 1.06E-02 9.80E-02 7 48 "KBTBD11,CELF1,AP4S1,GLDN,SLIT1,TMEM151B,DICER1" MicroRNA hsa-miR-597-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.07E-02 9.81E-02 6 37 "STAMBP,KCNJ10,PRKAB2,ZC4H2,PSD3,NAV2" MicroRNA hsa-miR-668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.01E-02 1.00E+00 1.07E-02 9.81E-02 6 37 "PHF12,TOMM20,MALT1,BTBD3,KLHL4,DHX33" MicroRNA hsa-miR-4721:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.03E-02 1.00E+00 1.09E-02 1.00E-01 9 72 "OGT,ARHGDIA,CBARP,PHYHIP,PLEKHM1,CHST15,ARHGAP12,PLCD1,CBX5" MicroRNA hsa-miR-3150b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-02 1.00E+00 1.11E-02 1.02E-01 5 27 "STX16,SLC35G1,LSAMP,RAB5B,RFX2" MicroRNA hsa-miR-3150a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.05E-02 1.00E+00 1.11E-02 1.02E-01 5 27 "STX16,SLC35G1,LSAMP,RAB5B,RFX2" MicroRNA hsa-miR-1199-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.07E-02 1.00E+00 1.13E-02 1.04E-01 10 85 "RGS11,TOMM20,CAMSAP1,CELF1,TDRKH,MUM1,NKD1,NFIX,NPTX2,ZXDA" MicroRNA hsa-miR-6793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-02 1.00E+00 1.19E-02 1.09E-01 7 49 "SLC22A6,PITPNM3,MPP2,SETD5,ATXN2,SOX5,NAV2" MicroRNA hsa-miR-3661:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-02 1.00E+00 1.19E-02 1.09E-01 7 49 "SFMBT2,LRWD1,SYNCRIP,SYTL4,MAT2A,KITLG,WBP2" MicroRNA hsa-miR-548q:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-02 1.00E+00 1.19E-02 1.09E-01 7 49 "PTBP2,CELF1,ZMYND11,MAPT,C5orf64,MEAF6,ZNF154" MicroRNA hsa-miR-6877-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.12E-02 1.00E+00 1.19E-02 1.09E-01 7 49 "NCBP3,LIMS2,ZKSCAN3,SP2,MPRIP,BHLHB9,TMEM63C" MicroRNA hsa-miR-1277-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-02 1.00E+00 1.20E-02 1.10E-01 4 18 "SPATA2,IL6R,KLHL23,AHCYL2" MicroRNA hsa-miR-933:PITA hsa-miR-933:PITA_TOP PITA 1.13E-02 1.00E+00 1.20E-02 1.10E-01 4 18 "MAP4K4,ZNF521,ZFHX4,POLR3H" MicroRNA hsa-miR-8078:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-02 1.00E+00 1.20E-02 1.10E-01 4 18 "GREB1,WDPCP,CAMKK2,SMUG1" MicroRNA hsa-miR-941:PITA hsa-miR-941:PITA_TOP PITA 1.13E-02 1.00E+00 1.20E-02 1.10E-01 4 18 "TAOK1,GAB1,NFIX,ST5" MicroRNA hsa-miR-6863:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.13E-02 1.00E+00 1.20E-02 1.10E-01 4 18 "MORC4,POGZ,AKNA,ATP6V0E2" MicroRNA hsa-miR-4288:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.11E-01 6 38 "CACNA1A,FOXF2,THYN1,PDPK1,FAIM2,SOX5" MicroRNA hsa-miR-4305:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.11E-01 6 38 "TAOK1,NCAN,FRMD5,KIT,SPART,ATP6V0E2" MicroRNA hsa-miR-219b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.11E-01 6 38 "LTBP4,CANX,SYNCRIP,TVP23A,GNAS,PREX2" MicroRNA hsa-miR-6821-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.11E-01 6 38 "EPB41,MSANTD4,TRAF3IP2,KIF3A,KCNJ5,WIPF2" MicroRNA hsa-miR-487a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.11E-01 6 38 "TMEM263,USP6NL,EN2,ZDHHC22,SLC36A4,FIGN" MicroRNA hsa-miR-3189-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.12E-01 8 61 "YTHDC1,EIF4G1,MDGA1,KCNK10,ZDHHC8,PPP3CB,CLUAP1,RPL7L1" MicroRNA hsa-miR-4529-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.15E-02 1.00E+00 1.21E-02 1.12E-01 8 61 "CARNS1,ABI2,IL6R,OPHN1,RMI1,AGTPBP1,TUBB2A,CADM2" MicroRNA hsa-miR-3186-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.19E-02 1.00E+00 1.25E-02 1.15E-01 3 10 "LRFN1,CACNA1B,TPPP" MicroRNA hsa-miR-122-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.22E-02 1.00E+00 1.29E-02 1.19E-01 9 74 "ACBD5,WDPCP,GRK4,HMGB1,GTDC1,ZFP30,TPCN2,ARL10,ERCC6L2" MicroRNA hsa-miR-6763-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-02 1.00E+00 1.29E-02 1.19E-01 5 28 "CPNE5,FRMPD4,TMEM151A,LSAMP,PTPRE" MicroRNA hsa-miR-521:PITA hsa-miR-521:PITA_TOP PITA 1.23E-02 1.00E+00 1.29E-02 1.19E-01 5 28 "OSBPL3,FAM19A1,MAST1,SOX11,CLASP2" MicroRNA hsa-miR-6786-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.23E-02 1.00E+00 1.29E-02 1.19E-01 5 28 "PNMA8B,AP1B1,GFER,FXYD1,KLC2" MicroRNA hsa-miR-152-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-02 1.00E+00 1.32E-02 1.21E-01 7 50 "IP6K1,STAMBP,KCNJ10,MPP2,C1orf109,ZC4H2,PSD3" MicroRNA hsa-miR-4633-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-02 1.00E+00 1.32E-02 1.21E-01 7 50 "PTPRT,HSF2,MMP17,NBL1,MTMR10,KIF21B,APOM" MicroRNA hsa-miR-6874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-02 1.00E+00 1.32E-02 1.21E-01 7 50 "PTPRT,HSF2,MMP17,MTMR10,MAP6D1,KIF21B,APOM" MicroRNA hsa-miR-6500-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.25E-02 1.00E+00 1.32E-02 1.21E-01 7 50 "PTPRT,HSF2,MMP17,NBL1,MTMR10,KIF21B,APOM" MicroRNA hsa-miR-4661-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-02 1.00E+00 1.36E-02 1.26E-01 6 39 "TAOK1,CLU,ZNF385A,TMTC1,MDM4,ARL10" MicroRNA hsa-miR-1909-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-02 1.00E+00 1.36E-02 1.26E-01 6 39 "CBR1,QKI,GPT2,SH3TC2,SEC31A,FBXW11" MicroRNA hsa-miR-154-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.30E-02 1.00E+00 1.36E-02 1.26E-01 6 39 "MMP16,KANSL1,FIGN,MCMBP,SYPL1,PMEPA1" MicroRNA hsa-miR-3918:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.33E-02 1.00E+00 1.40E-02 1.29E-01 9 75 "C6orf89,PRX,LDLRAD4,SEC16A,DMTN,NSG1,CSDC2,KPNA5,NFIX" MicroRNA hsa-miR-3159:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.35E-02 1.00E+00 1.42E-02 1.30E-01 10 88 "CAPRIN2,CLTA,ZFP28,CTNND1,SACS,C8orf37,SESN3,TMEM38A,MSANTD2,ZNF70" MicroRNA hsa-miR-3131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-02 1.00E+00 1.45E-02 1.33E-01 4 19 "BCL7A,TM9SF4,RFX2,ZNF74" MicroRNA hsa-miR-1263:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-02 1.00E+00 1.45E-02 1.33E-01 4 19 "NR3C1,PRRC2C,DICER1,THRA" MicroRNA hsa-miR-5091:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-02 1.00E+00 1.45E-02 1.33E-01 4 19 "SCARB1,SLC43A2,CHIC1,SSBP2" MicroRNA hsa-miR-3134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.38E-02 1.00E+00 1.45E-02 1.34E-01 8 63 "CTNND1,TUBA1B,TNRC6A,MPP2,OLA1,SLC25A36,POGZ,KAT6A" MicroRNA hsa-miR-631:Functional MTI Functional MTI miRTarbase 1.39E-02 1.00E+00 1.46E-02 1.34E-01 7 51 "SFMBT2,LRWD1,SYNCRIP,SYTL4,MAT2A,KITLG,WBP2" MicroRNA hsa-miR-1181:mirSVR_highEffct hsa-miR-1181:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.42E-02 1.00E+00 1.49E-02 1.38E-01 5 29 "ECSIT,RASSF8,TOX2,SYT9,FLRT1" MicroRNA hsa-miR-128b:Functional MTI Functional MTI miRTarbase 1.43E-02 1.00E+00 1.51E-02 1.39E-01 2 4 "EGFR,AFF1" MicroRNA hsa-miR-412-5p:TargetScan hsa-miR-412-5p TargetScan 1.43E-02 1.00E+00 1.51E-02 1.39E-01 2 4 "PCDH10,FICD" MicroRNA hsa-miR-3144-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-02 1.00E+00 1.53E-02 1.41E-01 6 40 "ATM,TOGARAM2,ELMSAN1,MYBPC1,ZNF713,OXR1" MicroRNA hsa-miR-1243:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-02 1.00E+00 1.53E-02 1.41E-01 6 40 "NLGN4X,SAMD5,SESN3,KSR2,MSANTD2,GPRIN3" MicroRNA hsa-miR-6808-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.46E-02 1.00E+00 1.53E-02 1.41E-01 6 40 "CHRDL1,TJAP1,SH3TC2,ATXN1,CNKSR2,SZT2" MicroRNA hsa-miR-5682:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-02 1.00E+00 1.59E-02 1.46E-01 8 64 "FEM1B,SH3GLB1,GOLGA7,NASP,GLDN,SLC30A10,SGK1,SMARCC2" MicroRNA hsa-miR-4277:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-02 1.00E+00 1.59E-02 1.46E-01 8 64 "UBXN2A,G3BP2,MTHFD2,NOVA2,PNMA3,SETD5,PEG10,ACSL6" MicroRNA hsa-miR-4690-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-02 1.00E+00 1.59E-02 1.46E-01 8 64 "PDXK,FCF1,DCTN4,DKK3,TNPO2,SBF1,EPN2,ZC3H4" MicroRNA hsa-miR-4758-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.51E-02 1.00E+00 1.59E-02 1.46E-01 8 64 "DNAH17,LONRF1,ZC3H11A,PNMA2,PKM,MRPS18A,CAMSAP2,NSD1" MicroRNA hsa-miR-885-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.56E-02 1.00E+00 1.64E-02 1.51E-01 9 77 "BCL7A,EPS15L1,GOLGA7,GABRB1,BRPF3,POLL,CELF3,AFF1,YPEL4" MicroRNA hsa-miR-1204:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-02 1.00E+00 1.65E-02 1.52E-01 3 11 "ANK1,BRPF3,DIP2A" MicroRNA hsa-miR-5705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-02 1.00E+00 1.65E-02 1.52E-01 3 11 "PRRC2B,CHIC1,TFIP11" MicroRNA hsa-miR-517b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-02 1.00E+00 1.65E-02 1.52E-01 3 11 "DBN1,NACC2,USP1" MicroRNA hsa-miR-937-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.57E-02 1.00E+00 1.65E-02 1.52E-01 3 11 "DCAF8,GLUL,CAMK2N2" MicroRNA hsa-miR-632:Functional MTI Functional MTI miRTarbase 1.64E-02 1.00E+00 1.72E-02 1.58E-01 6 41 "CACNA1A,FOXF2,THYN1,PDPK1,FAIM2,SOX5" MicroRNA hsa-miR-1287-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.64E-02 1.00E+00 1.72E-02 1.58E-01 6 41 "SIRPA,ATP13A4,KANSL1,RASGEF1B,TMEM151B,ZNF70" MicroRNA hsa-miR-525-3p:Functional MTI Functional MTI miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "PRX,ARRB1,ZBTB45,HSD11B1L" MicroRNA hsa-miR-6770-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "GPR37L1,EIF4G1,PKD1,NSD2" MicroRNA hsa-miR-585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "CDC25B,TMEM175,MSANTD4,ZNF154" MicroRNA hsa-miR-487b-3p:Functional MTI Functional MTI miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "MAGI2,GRM3,CPEB4,EVI5" MicroRNA hsa-miR-572:Functional MTI Functional MTI miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "ATM,LHFPL4,TMEM151B,WNT7A" MicroRNA hsa-miR-3648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "FOXK1,APC2,FKTN,NFIX" MicroRNA hsa-miR-1471:mirSVR_highEffct hsa-miR-1471:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 1.65E-02 1.00E+00 1.73E-02 1.59E-01 4 20 "CACNA1B,NRSN1,LINC01551,ANO4" MicroRNA hsa-miR-340-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.66E-02 1.00E+00 1.74E-02 1.60E-01 13 132 "ADCYAP1R1,EP400,FOXK1,MRO,NSG1,LUZP2,GRK4,AGBL5,RAB5B,PLEKHB2,C12orf49,PEX26,TAL1" MicroRNA hsa-miR-6510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-02 1.00E+00 1.77E-02 1.63E-01 7 53 "ZNF555,COL9A2,GAPVD1,IP6K1,SGSM2,ZNF331,ADAMTS17" MicroRNA hsa-miR-99b-5p:Functional MTI Functional MTI miRTarbase 1.69E-02 1.00E+00 1.77E-02 1.63E-01 7 53 "CNTNAP2,DYRK1A,ENO2,RAVER2,DDHD2,TRPS1,NPDC1" MicroRNA hsa-miR-3940-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.69E-02 1.00E+00 1.77E-02 1.63E-01 7 53 "CFAP410,NRXN3,ZNF585B,GPR75,NRGN,C12orf49,RXRA" MicroRNA hsa-miR-4507:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.80E-02 1.00E+00 1.88E-02 1.73E-01 8 66 "LCORL,DCAF5,PITPNM3,DLC1,NFYA,CNNM2,ATXN2,LINC00632" MicroRNA hsa-miR-15a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.82E-02 1.00E+00 1.91E-02 1.75E-01 9 79 "RNF157,LTBP4,IGSF6,CTNNA3,RSPO2,SLC1A2,MAPK8IP3,TMEM178B,CADM2" MicroRNA hsa-miR-4497:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-02 1.00E+00 1.92E-02 1.76E-01 6 42 "CBARP,SH2B1,ATP13A4,CAMK2N2,TPM3,UGT8" MicroRNA hsa-miR-4634:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-02 1.00E+00 1.92E-02 1.76E-01 6 42 "RNF157,CDC14B,TUBD1,SNX22,UEVLD,GPR161" MicroRNA hsa-miR-6772-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.83E-02 1.00E+00 1.92E-02 1.76E-01 6 42 "FOXK1,ZBED3,MPP2,RAB5B,PRRT2,NACC2" MicroRNA hsa-miR-6827-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-02 1.00E+00 1.95E-02 1.80E-01 12 120 "ADCYAP1R1,FOXK1,MRO,NSG1,LUZP2,GRK4,AGBL5,RAB5B,PLEKHB2,C12orf49,PEX26,TAL1" MicroRNA hsa-miR-602:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-02 1.00E+00 1.95E-02 1.80E-01 5 31 "TMEM132B,PDZD4,PPFIA3,DNAL1,MYO16" MicroRNA hsa-miR-220a:PITA hsa-miR-220a:PITA_TOP PITA 1.87E-02 1.00E+00 1.95E-02 1.80E-01 5 31 "GPR85,KCTD15,SLC25A36,EPB41L3,FBXW11" MicroRNA hsa-miR-409-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.87E-02 1.00E+00 1.95E-02 1.80E-01 5 31 "PDXK,NBEA,STAG2,RUFY2,VLDLR" MicroRNA hsa-miR-1180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-02 1.00E+00 2.04E-02 1.88E-01 8 67 "EIF1,RACK1,METTL21A,MDM4,KANSL1,FAM200B,HPS4,VPS35L" MicroRNA hsa-miR-1238-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.95E-02 1.00E+00 2.04E-02 1.88E-01 8 67 "DNAH17,LONRF1,ZC3H11A,PNMA2,PKM,MRPS18A,CAMSAP2,NSD1" MicroRNA hsa-miR-548ad-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.96E-02 1.00E+00 2.05E-02 1.88E-01 4 21 "APP,WAC,IQSEC3,NETO2" MicroRNA "GTCTACC,MIR-379:MSigDB" "GTCTACC,MIR-379:MSigDB" MSigDB 1.96E-02 1.00E+00 2.05E-02 1.88E-01 4 21 "EIF4G2,UBE2E3,CACFD1,ADGRL3" MicroRNA hsa-miR-551b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.02E-02 1.00E+00 2.10E-02 1.94E-01 3 12 "MAP4,MCMBP,STX1B" MicroRNA hsa-miR-4456:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-02 1.00E+00 2.13E-02 1.96E-01 7 55 "ENTPD4,TM9SF4,FUT10,PPM1L,YPEL4,CLASP1,C5orf64" MicroRNA hsa-miR-941:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-02 1.00E+00 2.13E-02 1.96E-01 7 55 "PWWP2A,NDST3,ECSIT,ITPKB,NFIX,CLSTN1,TRPS1" MicroRNA hsa-miR-5579-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.04E-02 1.00E+00 2.13E-02 1.96E-01 6 43 "CDC27,DNAL1,KATNAL1,CLDND1,ZNF711,DHX33" MicroRNA hsa-miR-1912:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.11E-02 1.00E+00 2.20E-02 2.03E-01 9 81 "XKR4,CFL2,FGF1,CSDC2,SON,ZSCAN29,ADAMTS17,TPM3,TBC1D15" MicroRNA hsa-miR-3115:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.13E-02 1.00E+00 2.22E-02 2.04E-01 5 32 "BRAP,DDX3Y,BTRC,TBPL1,HKR1" MicroRNA hsa-miR-4767:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-02 1.00E+00 2.33E-02 2.14E-01 7 56 "CASKIN1,TXNDC16,DNAH17,BRSK2,CPLX1,NUMA1,SSTR1" MicroRNA hsa-miR-6759-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.24E-02 1.00E+00 2.33E-02 2.14E-01 7 56 "AMPD3,SLC22A6,ZC3H12B,SDK2,SETD5,SOX5,NAV2" MicroRNA hsa-miR-1246:Functional MTI Functional MTI miRTarbase 2.27E-02 1.00E+00 2.36E-02 2.17E-01 6 44 "AXIN2,TAOK1,PYGO1,DYRK1A,MPP2,PTPRD" MicroRNA hsa-miR-1295b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.27E-02 1.00E+00 2.36E-02 2.18E-01 9 82 "XKR4,CFL2,FGF1,CSDC2,SON,ZSCAN29,ADAMTS17,TPM3,TBC1D15" MicroRNA hsa-miR-942-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.29E-02 1.00E+00 2.39E-02 2.20E-01 8 69 "TAOK1,APBB2,ARHGEF2,CTH,LILRA2,ZBTB45,PURG,STX1B" MicroRNA hsa-miR-1282:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-02 1.00E+00 2.40E-02 2.21E-01 4 22 "NRXN3,ACBD5,CYBB,SH3TC2" MicroRNA hsa-miR-132-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.30E-02 1.00E+00 2.40E-02 2.21E-01 4 22 "GPR153,NFE2L2,DIP2A,RGMB" MicroRNA "GGCGGCA,MIR-371:MSigDB" "GGCGGCA,MIR-371:MSigDB" MSigDB 2.31E-02 1.00E+00 2.40E-02 2.21E-01 2 5 "POM121,ZIC4" MicroRNA hsa-miR-4788:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-02 1.00E+00 2.40E-02 2.21E-01 2 5 "NFIX,SIGLEC10" MicroRNA hsa-miR-523-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.31E-02 1.00E+00 2.40E-02 2.21E-01 2 5 "LTBP4,KIAA0930" MicroRNA hsa-miR-1181:Functional MTI Functional MTI miRTarbase 2.31E-02 1.00E+00 2.40E-02 2.21E-01 2 5 "NKX2-2,SOX2" MicroRNA hsa-miR-6502-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.48E-02 1.00E+00 2.58E-02 2.37E-01 8 70 "SMIM17,APP,MICAL2,NCAN,AFF2,DRAXIN,BTBD3,ZNF70" MicroRNA hsa-miR-492:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-02 1.00E+00 2.60E-02 2.40E-01 6 45 "BID,GDA,GAPVD1,MAT2A,ST6GAL1,DHX33" MicroRNA hsa-miR-618:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-02 1.00E+00 2.60E-02 2.40E-01 6 45 "NR3C1,EFHB,DDR2,PDPK1,ACSL6,NUP214" MicroRNA hsa-miR-3675-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.51E-02 1.00E+00 2.60E-02 2.40E-01 6 45 "TBPL1,IP6K1,GRIK2,ZNF426,DNMBP,PUM2" MicroRNA hsa-miR-5708:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-02 1.00E+00 2.62E-02 2.42E-01 3 13 "BEST3,MTMR10,C12orf49" MicroRNA hsa-miR-3683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.53E-02 1.00E+00 2.62E-02 2.42E-01 3 13 "XKR4,NR1D2,NELFE" MicroRNA hsa-miR-95-3p:Functional MTI Functional MTI miRTarbase 2.53E-02 1.00E+00 2.62E-02 2.42E-01 3 13 "CANX,NXPH3,NSD2" MicroRNA hsa-miR-589-5p:Functional MTI Functional MTI miRTarbase 2.67E-02 1.00E+00 2.78E-02 2.56E-01 8 71 "PLEKHG5,MICAL2,GFRA1,KCTD15,RNASEL,TMEM136,TMPRSS5,TSN" MicroRNA hsa-miR-1306:PITA hsa-miR-1306:PITA_TOP PITA 2.68E-02 1.00E+00 2.78E-02 2.56E-01 4 23 "MSTN,NFIX,CEP41,ERC1" MicroRNA hsa-miR-3713:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-02 1.00E+00 2.78E-02 2.56E-01 4 23 "MSANTD4,C15orf41,C2orf72,TMCC1" MicroRNA hsa-miR-934:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.68E-02 1.00E+00 2.78E-02 2.56E-01 4 23 "KMT2C,FREM1,FAM126B,DDHD1" MicroRNA hsa-miR-1537-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-02 1.00E+00 2.81E-02 2.59E-01 5 34 "NDST3,NRXN1,CELF1,NAP1L1,PRKCB" MicroRNA hsa-miR-4776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-02 1.00E+00 2.81E-02 2.59E-01 5 34 "TTYH1,OGT,AGBL5,C2orf72,MAT2A" MicroRNA hsa-miR-3200-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.71E-02 1.00E+00 2.81E-02 2.59E-01 5 34 "EIF4G3,DCAF8,STX2,ARHGAP12,PSAT1" MicroRNA hsa-miR-433-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-02 1.00E+00 3.14E-02 2.89E-01 5 35 "SLC12A5,HOGA1,PEX26,UHRF1BP1L,ZNF621" MicroRNA hsa-miR-4787-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-02 1.00E+00 3.14E-02 2.89E-01 5 35 "ARHGDIA,MYADM,MTSS1L,PKD1,SNX22" MicroRNA hsa-miR-6861-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.03E-02 1.00E+00 3.14E-02 2.89E-01 5 35 "BRPF3,MAT2A,MYO18A,SIGLEC10,SPATA13" MicroRNA hsa-miR-517-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-02 1.00E+00 3.15E-02 2.90E-01 6 47 "MARCH4,CABP7,FRMD5,KIT,SNRK,TMEM151B" MicroRNA hsa-miR-6802-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.04E-02 1.00E+00 3.15E-02 2.90E-01 6 47 "CCNT1,TMEM170A,RABGAP1L,MTRF1L,SLC2A5,KIAA0930" MicroRNA hsa-miR-6886-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-02 1.00E+00 3.20E-02 2.95E-01 4 24 "FXYD6,TNPO2,ZFR2,ZFP91" MicroRNA hsa-miR-3195:mirSVR_highEffct hsa-miR-3195:mirSVR_nonconserved_highEffect-0.5 MicroRNA.org 3.09E-02 1.00E+00 3.20E-02 2.95E-01 4 24 "GRM7,TRIM46,TIE1,PITPNB" MicroRNA hsa-miR-126-3p.1:TargetScan hsa-miR-126-3p.1 TargetScan 3.09E-02 1.00E+00 3.20E-02 2.95E-01 4 24 "CAMSAP1,SAMD14,PEX5,RGS3" MicroRNA hsa-miR-3923:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-02 1.00E+00 3.20E-02 2.95E-01 4 24 "BTF3L4,RBPJ,MCF2L2,RBFOX2" MicroRNA hsa-miR-4718:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.09E-02 1.00E+00 3.20E-02 2.95E-01 4 24 "PRKCB,PSD,SBF1,URM1" MicroRNA hsa-miR-6084:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-02 1.00E+00 3.20E-02 2.95E-01 3 14 "AP1B1,CNDP1,JMJD1C" MicroRNA hsa-miR-339-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.10E-02 1.00E+00 3.20E-02 2.95E-01 3 14 "PITPNM3,HEYL,WDTC1" MicroRNA hsa-miR-5003-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.13E-02 1.00E+00 3.24E-02 2.98E-01 7 60 "ATP1A3,RAB39B,NPTX1,SEMA6D,CLASP1,ZNF106,TOM1L2" MicroRNA "ACGCACA,MIR-210:MSigDB" "ACGCACA,MIR-210:MSigDB" MSigDB 3.35E-02 1.00E+00 3.46E-02 3.19E-01 2 6 "EFNA3,ZNF827" MicroRNA hsa-miR-135a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.38E-02 1.00E+00 3.49E-02 3.22E-01 5 36 "CA8,SEPT7,RGS6,AMOTL2,ZNF138" MicroRNA hsa-miR-1258:Functional MTI Functional MTI miRTarbase 3.38E-02 1.00E+00 3.49E-02 3.22E-01 5 36 "TXNDC16,ANKRD46,PACSIN1,SETD5,TRIM2" MicroRNA hsa-miR-1287-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.39E-02 1.00E+00 3.50E-02 3.23E-01 7 61 "GAS7,BSCL2,PNMA2,AGBL5,MYCN,GPR137C,ROBO1" MicroRNA hsa-miR-4798-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.54E-02 1.00E+00 3.65E-02 3.37E-01 4 25 "MPP6,ELOVL5,USP51,TMOD2" MicroRNA hsa-miR-6829-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.56E-02 1.00E+00 3.68E-02 3.39E-01 8 75 "PRX,PHF19,KBTBD12,RAPGEF1,MAP4,PKM,PLCD1,WBP2" MicroRNA hsa-miR-6822-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.62E-02 1.00E+00 3.73E-02 3.44E-01 9 89 "AKAP12,GOLGA7,FRMD5,PKM,SMOX,SLC8A1,FBXL16,TRPS1,MEAF6" MicroRNA hsa-miR-5591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.64E-02 1.00E+00 3.76E-02 3.46E-01 6 49 "TBRG4,E2F6,ATP13A4,ZHX1,NAP1L1,SEZ6L" MicroRNA hsa-miR-718:Functional MTI Functional MTI miRTarbase 3.73E-02 1.00E+00 3.85E-02 3.55E-01 3 15 "ADCY5,CNDP1,JMJD1C" MicroRNA hsa-miR-671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.73E-02 1.00E+00 3.85E-02 3.55E-01 3 15 "SORCS2,DIS3L,FAM208A" MicroRNA hsa-miR-516a-5p:PITA hsa-miR-516a-5p:PITA_TOP PITA 3.73E-02 1.00E+00 3.85E-02 3.55E-01 3 15 "FIGN,STX1B,PLCB1" MicroRNA hsa-miR-3651:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-02 1.00E+00 3.87E-02 3.56E-01 5 37 "ZBTB10,STAG2,OLA1,TMEM151B,RPL7L1" MicroRNA hsa-miR-4764-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.75E-02 1.00E+00 3.87E-02 3.56E-01 5 37 "DDO,LRIG1,MED12L,ZNF274,BDP1" MicroRNA hsa-miR-323b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-02 1.00E+00 4.14E-02 3.82E-01 4 26 "PITPNM3,ERBB2,MSR1,UHRF1BP1" MicroRNA hsa-miR-4785:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-02 1.00E+00 4.14E-02 3.82E-01 4 26 "MYADM,SPATA2,LIFR,DBNDD2" MicroRNA hsa-miR-181d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.02E-02 1.00E+00 4.14E-02 3.82E-01 4 26 "HCN2,ING4,TNK2,C2orf72" MicroRNA hsa-miR-1292-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.36E-02 1.00E+00 4.49E-02 4.14E-01 12 136 "SLC24A4,TRMT9B,CDC14B,LETMD1,EPB41,KIF3A,IL6R,TMEM145,ZNF793,ALG9,ATAT1,DRAXIN" MicroRNA hsa-miR-126:mirSVR_highEffct hsa-miR-126:mirSVR_conserved_highEffect-0.5 MicroRNA.org 4.42E-02 1.00E+00 4.56E-02 4.20E-01 3 16 "CFAP61,PPP3CB,CNKSR2" MicroRNA hsa-miR-524-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-02 1.00E+00 4.56E-02 4.20E-01 3 16 "PRX,ZBTB45,HSD11B1L" MicroRNA hsa-miR-6723-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.42E-02 1.00E+00 4.56E-02 4.20E-01 3 16 "ACBD5,FBXO25,KLHL23" MicroRNA hsa-miR-563:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-02 1.00E+00 4.67E-02 4.30E-01 4 27 "PNKD,RUBCN,SPATA2,FNBP1" MicroRNA hsa-miR-4796-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-02 1.00E+00 4.67E-02 4.30E-01 4 27 "PTCHD1,NFS1,CD99L2,INPP5B" MicroRNA hsa-miR-937:PITA hsa-miR-937:PITA_TOP PITA 4.53E-02 1.00E+00 4.67E-02 4.30E-01 2 7 "NEUROD2,POLR3H" MicroRNA hsa-miR-5188:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.53E-02 1.00E+00 4.67E-02 4.30E-01 2 7 "MICAL2,KSR2" MicroRNA hsa-miR-3130-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-02 1.00E+00 4.80E-02 4.42E-01 6 52 "SDE2,DDX19B,NEGR1,CCDC80,ATF7IP,WNK3" MicroRNA hsa-miR-4482-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-02 1.00E+00 4.80E-02 4.42E-01 6 52 "SDE2,DDX19B,NEGR1,CCDC80,ATF7IP,WNK3" MicroRNA hsa-miR-4641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.67E-02 1.00E+00 4.80E-02 4.42E-01 6 52 "BTF3L4,SRARP,FTO,SGK1,STX1A,AJAP1" Drug ctd:D003042 Cocaine CTD 1.60E-49 7.84E-45 7.84E-45 8.92E-44 415 1317 "ABAT,SYN3,CLK4,AS3MT,ACTN2,NDRG2,GALNT16,ADCY2,SLITRK1,ADCY8,PNMA8B,ADORA1,ADORA2A,ADRA1B,KIDINS220,SLC24A4,MTUS1,HECW2,AGT,OSBPL1A,TBC1D14,PLA2G6,C1QTNF1,LRRC7,SPARCL1,SEMA6A,C1QTNF4,ALCAM,KCNT1,SYT13,BEGAIN,AMH,SEMA7A,ANXA7,PPFIA3,APP,CDC14B,SEMA4G,ARHGAP5,ARNTL,RGS20,DYNLL1,ATM,ATP1A1,ATP1A3,SLC4A4,ATP1B3,MYOM1,RIPK1,AZGP1,BACH1,BCHE,RGS9,HCN2,NRP2,BID,CFLAR,LDHD,CDK5R1,ARHGEF7,FUBP1,BTK,CA4,CALM1,KALRN,CAMK2A,CAMK2B,RUNX1T1,CBLN1,LDB2,CCKBR,KRIT1,INA,AIFM1,ARHGEF1,SCARB1,ENTPD2,CD81,LRRFIP1,LARGE1,CHN1,CHRM4,CHRNA4,RAB3C,CHRNB2,CLU,SLC24A2,CLTB,TJP2,TMEM184B,HOMER3,CNR1,WHRN,MAGED1,CLOCK,PREPL,CREM,CRY2,RNF14,SLC32A1,SNCAIP,TENM4,CSF2RA,SIPA1L1,NCAN,PDE4DIP,CALY,APPL1,CTNND2,GPSM1,CYBB,GPRASP1,SNPH,DCAF8,ACY3,AIF1L,JAKMIP2,ELMO1,TIAM2,SNAP91,DLG2,DLG4,GRIN3A,DNM1,HS3ST2,DYNC1I1,DNM2,DPYSL2,DRD1,DRP2,FAM78B,ABCC5,ABCC9,EDN1,EDNRA,EDNRB,EEF1A2,KLHL5,EFNA2,EFNA3,RBM12,EFNB3,APH1A,EGFR,EGR3,BSCL2,ENO2,EPHA5,EPHB1,NCALD,RCSD1,EYA1,NRN1,PTK2B,ST3GAL6,FDFT1,PPP1R1B,OLFM1,FGF12,FGFR1,ATP5PD,HPCAL4,CAP2,AGAP2,SEMA6C,SEMA4D,FLYWCH1,SYT3,CSPG5,ADGRA1,MEGF10,GABBR1,GABRA1,GABRB1,GABRB3,GABRG2,GAD1,GAD2,RAPGEF6,ARPP21,GAP43,CPLX1,TUBA8,GFAP,NFU1,GFRA2,KIRREL3,GJB1,PCSK1N,GNAO1,GPM6A,GPM6B,ATF7,GPER1,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,SPACA9,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,ATE1,GRM1,GRM2,GRM3,GRM5,GRM7,GSN,KIF3A,GUCY1A1,GUCY1B1,GYG1,FRMD5,BACH2,HSP90AA1,HTR2A,IDH3A,ITPKB,JAK1,KCNA2,KCNA6,KCNB1,KCND1,KCND2,KCND3,KCNJ4,KCNJ10,KCNJ11,LAMP2,LSAMP,MAOB,MAP2,MAP6,MARK1,MAT2A,MBD1,MBP,SYT9,MOBP,PTOV1,TAGLN3,MYH6,MYH7,MYO5A,NCF2,NEFM,NEFH,NF1,NFIX,NKX2-2,NOS1,NPY,NPPA,NPTX2,NTRK2,DDR2,GPR88,OPHN1,CLDN11,OXTR,PBX1,PCDHGC3,PCDH8,PCSK2,CDK18,PDPK1,PDYN,PENK,OLA1,ZDHHC8,GDAP1L1,SERPINI1,SEMA5B,PKM,PLEC,PLP1,SLC25A23,NECAB2,RETREG2,SEPT4,POLR2F,PPP2R2B,PPP2R2C,PPP3CA,PPP5C,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,MAPK10,PTK2,PTN,PTPRB,CASTOR1,PEX2,RAB3A,RASGRF1,CRTAC1,DPF2,RGS4,RORB,BAALC,RTKN,CLIP1,STX1B,RYR3,AP1AR,S100B,SATB1,ATXN1,SCN2B,MRAS,SGK1,AMBRA1,R3HDM2,CNKSR2,SYBU,SLC1A2,SLC4A3,DHX30,SMTN,LIMS2,PKNOX2,CCDC88A,SHANK2,SLC14A1,SLC20A2,SORCS3,SNCB,SNCA,FAIM2,SON,KDM3A,ZHX3,SPTAN1,RBM26,TROVE2,SSTR1,SSTR2,ERBIN,MAPK8IP3,SEPT8,STXBP1,SYT11,SUPT5H,PLCB1,SYN1,ARC,SYN2,SYP,SYT1,SYT4,SYT5,TAC1,TACC1,TACR1,SEMA4A,DNMBP,ADGRL3,TCF4,SATB2,SYNE1,PCDHGA1,OBSL1,ARHGAP9,CRTC1,PCDHA2,TF,DICER1,ZFPM2,HHIP,SLC44A1,THRA,ENHO,NACC2,RELL2,TMPO,TNFRSF1B,PRRT1,SEZ6L,TPM3,SYNPO2,FNDC5,SGK3,FAM155A,UBE3A,UBTF,UCHL1,PLPPR2,ZBTB16,ANKS1B,TFIP11,PMEPA1,MFF,PRDM2,SCG2,SEMA3B,SLC17A7,SNX27,KCNAB1,CAB39L,WNK3,SLC17A6,AMN1,CAMK1G,PIANP,NETO2,SLC4A10" Drug ctd:C029790 "2,2',3',4,4',5-hexachlorobiphenyl" CTD 1.67E-35 8.18E-31 4.09E-31 4.65E-30 497 1885 "VWA5B2,SDE2,ABR,ASIC2,ACHE,ACLY,FAM43B,ARID1A,CSMD3,DSCAML1,SLC12A5,SORCS1,USP31,TEX22,SNX32,WDR35,ADGRF5,SEMA6A,C1QTNF4,SPOP,ARHGAP20,AMH,AMPH,BIN1,OGT,CDC42BPA,DPP10,ANK1,ANK3,EP400,PPFIA4,ANXA7,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,ASGR1,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,NUMB,ATM,ATP1A1,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,NOL4,ATP6V1G2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,MAP7,RUNX1T1,PRC1,CCK,SLC5A11,CD38,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN1,CHN2,CHRM1,PLEKHB1,LHX2,SLC22A6,DLGAP3,NRXN3,PLAA,CLTC,HOMER3,SLC25A27,COX4I1,ACBD5,ZNF521,MFSD4A,NSL1,CREM,ENTPD4,SLC32A1,ARHGEF10,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,ARHGEF4,CTNND1,NRSN1,SEC14L5,FRMPD4,MATR3,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,ZEB2,MFAP3L,MAGI2,TMEM130,LYPD1,ALKBH8,SACS,SPOCK3,SV2A,NTM,AK5,SGSM2,DLG2,DLG4,DMD,DNM1,HS3ST2,CDON,DNM2,SHANK1,DSCAM,DTNA,DTNB,EBF1,USH1C,SNX29,SGK2,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,PLXNC1,TMEM132E,EIF5,ELAVL2,PLEKHA1,ENO2,EPB41L1,EPHA5,KCNMB2,EFS,APC2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,F5,RPS6KC1,TUBA1B,PTK2B,ZIC4,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,FGFR3,ATP5PD,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FLT1,NBEA,SMC2,CAMKK2,CELF1,STAU2,PNMA2,KBTBD12,B3GAT1,TBR1,NRG3,GAA,GALNT15,GALR1,ZNF274,DISC1,SRRM4,WASF3,CPLX1,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,GLUL,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,GNAS,PSRC1,PRUNE2,TDRKH,B4GALNT4,GPR37,CECR2,CNTRL,RFFL,GRIN1,GRIN2C,ATE1,GRM5,ZNF496,GSN,RNF165,PTPN5,IL1RAPL1,GSTT2,ZBTB49,BVES,FAM107A,TMEM179,HAS2,NXPH3,HRH3,KLF12,HNF4G,IGFBPL1,CPT1C,DHX35,HSP90AA1,HTR2A,MYLK2,SOWAHA,IGF1,NKD1,DOCK7,KNDC1,DISP2,SCRT2,IL12A,BRINP3,SLC6A17,INSM1,LRRTM3,ITPKA,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,LSS,MAG,MAP6,MBP,IL17D,KITLG,MOBP,MOG,MPP2,CPNE9,ADAM22,MSR1,MDGA1,MYCN,MYT1,HNRNPM,NASP,NCAM1,RCOR2,NEFM,NEFH,NELL2,NFIX,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PC,PCDH9,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,PKM,KCTD15,ST8SIA5,FXYD1,PLP1,PURG,NECAB2,TNPO2,FAT3,POU3F2,PPP2R2B,LRRN3,PTPA,VSTM2L,PRKACB,PRKCG,MAPK3,MAPK9,SLC26A11,DIRAS2,PSD,SYTL2,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRH,PTPRN2,PYGM,TUG1,RAB5B,TMEM255A,ACSS3,SH3TC2,IQSEC3,SUSD4,RET,PRRT2,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,RTN1,STX1B,S100B,DRAXIN,SCN2A,SCN4B,SMPD3,ASIC4,IL17RB,SOX6,KIF27,ITSN1,SH3GL2,PPM1E,ST6GAL1,CCDC92,CLSTN1,SLC1A3,SLC1A6,RUFY2,LRRC55,SLC6A8,SLC8A1,SHANK2,SLCO1A2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,SNAP25,SNCA,FAIM2,UNC80,USP33,KIF21B,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,SPTAN1,KIF1B,SST,NKAIN2,ADHFE1,AJAP1,NECAB1,FGD4,SYNE2,VAMP1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,VWCE,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TIE1,TIMP4,RELL2,ASXL3,TPM1,TPM3,TPM4,DOK6,PRMT8,TTC3,TTPA,CLHC1,NSD2,ETNPPL,KCNK12,ZNF184,DPYSL5,PROCA1,ANKS1B,FTSJ1,RGMA,GDPD5,PRDM8,XKR7,NAV2,SLC17A7,TMEM163,ITM2C,SLC17A6,RGS7BP,FAM13C,HNRNPA3,GJC2,ACTR3B,PIANP,DPF3,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:C496932 panobinostat CTD 2.79E-34 1.37E-29 4.56E-30 5.18E-29 380 1335 "ABAT,ASIC1,AS3MT,EMILIN3,TKTL1,XKR4,SLC25A25,ADCYAP1R1,AXIN2,UNC5A,RNF150,PTCHD1,SORCS2,CC2D2A,C1QTNF4,ALCAM,PCDH10,BEGAIN,USP28,EPB41L5,GAS7,SFMBT2,ARHGAP5,ARRB1,ASCL1,ASTN1,RNF182,NOL4,NRP2,CFLAR,LDHD,BMP7,BMPR1B,DST,JAZF1,CA4,CA8,CA12,CACNA2D1,CACNB2,CALB2,SPAG9,RUNX1T1,CCKBR,SLC16A4,CDH2,CDH8,CDH10,DCLK1,LRRFIP1,CDH18,CLGN,NOG,ADGRG1,CHGA,SYNPR,RAB3C,SLIT2,LHX2,RAB33A,NRXN2,CLU,NGEF,ABCG2,CNTN1,FAM149A,COL9A3,ZNF521,IGDCC3,CNRIP1,C2CD2,AKAP12,HAPLN1,TRIM69,CSF2RA,LRIG1,FEZ1,LRRC3B,PDE4DIP,KIAA0040,CTNND2,DCAF4,BOC,ARHGAP24,TOX,PABPC5,BRINP1,DCC,ZNF804A,C8orf34,MFAP3L,MAGI2,RABGAP1L,ARNT2,KBTBD11,DYNC1I1,CDON,RCAN1,EBF1,ST8SIA3,EDN1,EDNRA,EDNRB,EBI3,PLXNC1,LPAR6,PCOLCE2,LRRC17,RASGRP2,SEZ6,DENND4A,NCALD,CEP85L,TMEM74,ETV1,PIPOX,ADGRV1,DLC1,CHST15,SLC9B2,SPSB4,FGFR3,SYNCRIP,ATP13A4,FLT1,DACH2,CSPG5,FUT9,TVP23A,HRASLS5,GABRB3,DENND2A,GAD1,GAD2,SALL3,GAP43,ERAP1,DNER,FAXC,GBX2,ADAM28,FREM1,GLS,TOX3,MAP7D2,KCNMB4,DCLK2,GNAS,LNX1,PRUNE2,DIPK1C,TDRKH,STON1,GPR37,STMN2,GRIA1,GRIK3,GRM3,PTPN5,IL1RAPL1,KAT7,GUCY1A1,HAS2,IGSF21,TOX2,SCRG1,HNMT,NEGR1,SHISA6,CELF5,MSL1,IDH3A,IFI16,NKD1,KIAA1755,HES5,LIX1,ZNF385B,LRRTM1,METTL21A,OLFM3,KCNC1,KCND2,KCNJ3,KCNK1,KCNN3,KIF5C,KIT,L1CAM,LAMA2,TMEM110-MUSTN1,LAMP2,LIFR,LMO2,SYTL4,FGFBP3,NCOA7,MAP2,MAP6,SHC3,MEF2C,MEIS2,MGAT3,KITLG,CD200,ADAM22,SCG3,RSPO2,MYCN,LAYN,NEXMIF,BEX5,NDP,NEFM,NELL1,NELL2,NF1,NFE2L2,ALDH1L2,CNOT4,NPY,OPCML,ZNF827,KCNK10,PAK3,PAX6,DPY19L2P2,PCDH8,PDE3A,PDE4D,PDGFRA,ENPP2,PDYN,GPR173,TMOD2,OLA1,PFKP,PKM,PLP1,HMGCLL1,PURG,LRP12,PRRX1,FAT3,SH3KBP1,IRX1,PPP1R1A,ZFHX4-AS1,PPP2R2B,LRRN3,PRKCB,MAPK3,MAPK10,PRODH,RELN,SYTL2,SNRK,ELOVL2,STK32A,PTPRN2,PTPRO,PID1,ENOX1,FEZF2,VEPH1,FIGN,RFX3,RFX4,ROBO2,ARMH4,SOX8,WLS,RTN1,RYR3,S100B,AMER2,MIR124-2HG,SEMA6D,CSRNP3,SCN2B,SCN4B,SCN7A,ELMOD1,ZFP2,HSPA4L,PPP1R9A,ARX,FERMT1,FHOD3,CNKSR2,NLGN1,SLC1A3,PKNOX2,LRRC55,SLC6A8,SLIT1,GKAP1,COA1,LIMCH1,RIMS1,SNAP25,KIF13A,SOX2,SOX3,TNIK,SOX10,SOX11,DOK5,NMNAT2,SPP1,CDK19,NFASC,LMO3,CLSTN2,COLGALT2,STOX1,SMOC1,SST,EPB41L3,SOX21-AS1,SULF2,AJAP1,FAM168A,SYT11,ADAMTS17,COBL,SYT4,ASTN2,TAC1,POPDC3,TACC1,CNTN2,ADGRL3,WWC1,ZEB1,SYNE1,DOCK9,SLC19A3,SLC35G2,RNF175,FAM200B,HHIP,HEY2,FAM124A,TRPS1,ZMYND8,FNDC5,SSBP2,RFTN2,TUBB2A,SGK3,RPRM,FAM155A,FRRS1L,UGT8,FLRT2,CCDC136,LMF1,RBFOX3,NSD2,PCDH20,ZIC1,ZIC3,TRIM9,ZBTB16,ANKS1B,SLC30A4,PMEPA1,LRP8,RGMA,TUBA1A,TMEM178A,NAV3,TMEM163,FAM13C,FZD3,KAT6A,PHTF2,ST8SIA2,CPNE4" Drug CID000004376 N-methyl-DL-aspartic acid Stitch 8.54E-34 4.18E-29 1.05E-29 1.19E-28 227 655 "ACHE,ADCY8,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,LRFN2,LRRC7,BEGAIN,AMT,APBA2,APLP1,DDO,APP,CASK,BCHE,CACNA1I,CACNA1G,BSN,CA4,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALB1,CALB2,CALM1,NGB,CAMK2A,CAMK2B,CAMK2D,CAMK2G,RHBDL1,CCK,KRIT1,AIFM1,LRBA,CDH2,MAGI1,DLGAP1,CACNA2D2,ASIC3,CHRM1,CHRNA4,CHRNB2,CNR1,PICK1,AKAP5,NRG2,CREM,SLC32A1,NOS1AP,BOC,ARHGAP32,MATR3,DAPK1,DBI,DBN1,MAGI2,DLG2,DLG3,DLG4,GRIN3A,SHANK1,DRD1,DTNB,CACNG7,EFNB3,EIF4G2,ENO2,DMTN,GPHN,STX2,EPS8,ERBB4,ADGRV1,NRN1,CACNG3,CACNG2,PTK2B,PPP1R1B,BAIAP2,AGAP2,SYT3,FOLH1,CAMKK2,NSG1,B3GAT1,NRG3,FYN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,INPP5K,GFAP,NTNG2,TTBK1,GLRB,GLS,PCSK1N,GNAS,STMN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GUCY1A2,GUCY1B1,HTR2A,KCNA1,KCNA4,KCND2,KCNJ16,CAMK2N2,MAOB,MAP2,MAP4,ADAM22,NCAM1,NOS1,NPY,NPR2,NRGN,NTRK2,NTRK3,OGDH,OPRL1,PAH,PDE2A,PDYN,PENK,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKD1,GPSM2,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK9,PRODH,RELN,PTCH1,PTK2,PTN,RAB3A,RAB5B,ENOX1,RASGRF1,RASGRF2,GLDN,RYR1,RYR3,SALL1,SCN4B,NLGN1,SLC1A2,SLC1A3,RPH3A,SLC1A7,SLC6A9,SHANK2,CPEB4,RIMS1,SCN3B,SOX10,SST,JMJD6,ARC,SYN2,SYP,TAC1,TAC3,TACR1,TPCN2,TIAM1,ICAM5,CABIN1,TRIO,TRPC1,PORCN,SLC30A3,LRP8,SLC17A7,SLC17A6,CAMK1G,NUP214,NETO2,NETO1" Drug ctd:C046012 pentanal CTD 2.68E-31 1.31E-26 2.63E-27 2.99E-26 412 1531 "VWA5B2,ABAT,FAM43B,GALNT16,DSCAML1,TMCC3,ADRB2,SLC24A4,OSBPL6,TXNDC16,PLA2G6,C1QTNF3,SRPX,CEP126,MARCH4,GOLGA7B,PDZD4,BEGAIN,ZFAT,MAGEE2,BCAS1,MIER1,CDK10,SFMBT2,PPP4R4,IGDCC4,ARHGDIG,ARRB1,PLA2G4C,DACT3,TMEM108,ATM,ATP1A3,RNF182,ALDH7A1,CADM3,KIF1A,TTC9B,ADGRB1,RGS9,LMCD1-AS1,CFLAR,BMP7,ARHGEF7,CACNA1G,GPC2,BAIAP3,IL33,LDLRAD4,CFAP410,CA4,LURAP1,CALB2,DIRAS1,CCK,CCKBR,KRIT1,SLC5A11,INA,DCLK1,CRLF1,CHI3L2,PLEKHB1,CASC2,ARHGAP22,LHX2,DLGAP3,RAB33A,NRXN2,SLC24A2,NGEF,RAB26,FAM149A,COL9A2,ZNF521,IGDCC3,CP,CLOCK,CREB5,CRMP1,SLC32A1,CRYM,CSF1R,CSF2RA,FEZ1,GALNT9,CHD5,RIMS4,PDE4DIP,SDC3,CMTM5,ARHGEF4,ARHGAP24,DCAF8,RASSF2,RIMS3,MAML1,DAPK1,AIF1L,KIAA0319,KLHL3,TMEM130,LYPD1,GUCD1,CCDC3,KIF19,ZNF582-AS1,MED12,NR1D2,CPEB2,DUSP9,EEF1A2,RASGRP1,TMTC1,CACNG7,FAM13A,EBI3,MRO,KMT5B,PLXNC1,C8orf37,PAN3,RASGRP2,TMEM74,RRAGB,CEND1,F5,REEP2,PSMA3-AS1,EFEMP1,FKTN,GORAB,GTF2IRD2,HPCAL4,C1orf61,AGAP2,SYT3,EFCAB2,SORBS1,KHDRBS3,ST6GALNAC3,NSG1,TMEM151A,TBR1,FYN,MEGF11,DKK3,GAD1,HBS1L,BRPF3,JPH4,GATM,FAXC,GBX2,GPR162,GFRA1,MALT1,HPGDS,AIFM3,KCNMB4,DCLK2,GNAO1,GOLGB1,STON1,GPR37,TMEM121B,CNTRL,DIDO1,C1QL4,GRIK2,ADAMTS8,CIT,BTN2A1,LINC00839,MFSD2A,LINGO1,ADAMTS6,GUCY1B1,SLC2A6,CELF3,TOX2,PADI2,NXPH3,FRMD5,HMX1,HNMT,HPR,ATCAY,ICA1,IRF8,BTBD17,MSL1,SHISAL1,LRRC25,NKD1,NIM1K,IGSF1,IL6R,TUBB2B,ITGA7,C2CD4C,KCNF1,KCNH2,KCNMA1,KCNN1,CREG2,KIF5C,LINC00634,KLRC3,L1CAM,LRRC4B,CAMK2N2,LMO2,NAT8L,MAPT,MBP,SYT9,CHST6,ADAM11,MGAT3,SCAMP5,XRRA1,MOV10,MX1,LAYN,NEXMIF,MYT1,FXYD7,NAP1L3,RCOR2,NEFM,CCDC13,NEUROD2,NFIA,CNOT4,NOVA2,NPTX1,NRGN,OLR1,OPHN1,ZNF713,P2RY1,ZNF827,ZDHHC22,GLIPR1L2,DPY19L2P2,PCDH9,PDE2A,PDE3A,PDE4D,PDGFRA,PDPK1,GNG2,OLA1,ZDHHC8,DUSP26,SERPINE2,CAMKV,TMEM38A,KCTD15,JAKMIP1,FTO,PLIN1,CDIP1,NECAB2,ING3,SEPT4,FA2H,FSD1,PPARA,PPP2R2B,VSTM2L,RASGEF1B,PRKACB,MAPK8,MAPK10,GRAMD1C,SMIM10L2B,PRPH,GDPD1,LAMA1,CNTLN,PTX3,PEX2,TMEM231,PID1,TMEM255A,FAM66C,FAT4,FAM184A,RAP1GAP,RASGRF2,RADX,SLC6A15,RET,ERI2,FIGN,RNASE1,ZNF532,TMLHE,KLHDC8A,CARF,NEK11,EPHA10,RPS6KA2,MAP6D1,LRRK2,CNTNAP3,MEG3,SOX8,ATAT1,KCNIP3,ATXN1,SCN4B,SCP2,TNFRSF19,ELMOD1,FERMT1,CPEB3,MYO18A,ABLIM3,SLC1A2,ZNF365,FAM81A,LIMS2,SLC6A8,SLC8A2,SLC8A1,RTP5,SLC14A1,EFHD1,BTBD7,SPHKAP,TET1,SLN,MAST1,OGDHL,SORCS3,SNCA,KIF13A,NMNAT2,KDM4C,UNC5B,ZC3H13,DBNDD2,NFASC,SSTR2,ELOVL4,STAC2,SULF2,SEPT3,ARHGEF9,ARC,SYN2,SLC37A2,CAMTA1,NR2F1-AS1,WSCD1,TCF7,CLASP1,NAT16,DOCK9,FAM189A1,OBSL1,ARHGEF12,GPRIN3,PCDHA3,PCDHA1,TF,FBXL16,ENHO,TIAM1,ERCC6L2,BEX4,TNNT1,RASD2,TPM1,NPL,TRO,HIRA,RPRM,LINC00689,VAV1,VGF,LMF1,LAT2,TCEAL7,CELF4,ZNF154,REEP1,DPYSL5,ANKS1B,SLC30A3,PMEPA1,EMSY,PRDM8,NAV3,WNK2,EPM2A,HRASLS,ZNF37BP,TMEM63C,PHTF2,NLRP3,ZNF248,TIGD6,ADAMTS10,PIANP,RNF146,PRRT4,SENP7,JPH3" Drug CID000000611 glutamate Stitch 6.27E-30 3.07E-25 5.12E-26 5.82E-25 288 962 "ABAT,ASIC2,ASIC1,ACHE,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRA1D,SEMA6A,SYT13,APLP1,ALS2,DDO,AQP4,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,RIPK1,BCS1L,CACNA1I,CACNA1G,BSN,CA4,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALB1,CALB2,CALM1,CAMK2B,CAMK2D,CBS,KYAT1,CCK,CCKBR,KRIT1,AIFM1,CD38,LRRFIP1,DLGAP2,CDO1,CACNA2D2,CHI3L2,ASIC3,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,SULT4A1,HOMER3,CNR1,PICK1,SLC4A7,NRG2,CPS1,CREM,SH2B1,SLC32A1,GDA,CS,CALY,PLCXD3,EARS2,ACY3,DAPK3,SV2A,DLG2,DLG4,GRIN3A,SLC25A18,DRD1,DTNB,AASDH,EEF1A2,SGK2,CACNG7,AASS,EIF4G2,OLIG2,ENO2,GPHN,NRN1,CACNG3,CACNG2,PTK2B,PPP1R1B,ACTL6B,AGAP2,FOXM1,FOLH1,CSPG5,B3GAT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,DISC1,INPP5K,GART,CPLX2,DNER,GCK,TUBA8,GFAP,GGT7,GGT5,TCERG1,COPS8,GLRB,GLS,GLUL,PCSK1N,GNAS,GPT2,GPD2,STON1,MCHR1,GRIA1,GRIA2,GRIA4,PLCD4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,ATE1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GSTT2,ATXN2L,HTR2A,ATCAY,IDH3A,IDH3B,IGF1,NKD1,KCNA1,KCNA2,KCNA4,KCND2,KCNJ3,KCNJ10,KCNJ16,KCNMA1,LIG4,PACRG,MAOB,MAP2,MAP4,MAPT,MAT2A,KITLG,MTR,NEFM,NFE2L2,NOS1,NPY,NRGN,HCN1,NTRK2,NTRK3,OGDH,OPRL1,P2RX7,P2RY1,PAH,PC,PDYN,PENK,ABCB1,PKD1,PKM,GPSM2,PLCB2,PLCD1,PLEC,PSAT1,PPP3CA,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK10,PRODH,PRPH,PRPSAP2,RELN,KLK6,APTX,PTK2,RAB3A,RYR1,RYR3,S100B,MAPK12,SCN4B,SGK1,SHMT2,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A9,SLC6A11,IFT122,RIMS1,SNAP25,SCN3B,SOX10,NMNAT2,SPP1,ERC1,BEX1,NPAS3,NFASC,SST,STX1A,PLCB1,SYN1,SYN2,SYP,SYT1,SYT4,TAC1,TAC3,TACR1,MLST8,AZIN2,ACTR6,BHLHB9,ZFP91,CABIN1,NPL,TPM3,TRPC1,TRPC3,TRPM2,SGK3,UBC,VGF,PORCN,SLC13A3,ETNPPL,SLC30A3,SLC38A1,STMN4,SLC17A7,PLD4,SLC17A6,NETO2,JPH3" Drug CID000000813 potassium Stitch 1.26E-27 6.17E-23 8.81E-24 1.00E-22 292 1009 "KCNH8,ASIC2,ASIC1,METAP1D,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,BRAP,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRB2,SLC24A4,AGT,BBOX1,DPP10,ANK3,PHF12,KCNAB2,APOC2,AQP4,PDXK,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,AZGP1,HCN2,NAE1,CACNA1I,CACNA1G,BSN,WASF1,CA4,CACNA1A,CACNA1B,CACNA1D,CACNA1E,DDR1,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,CAMK2B,CAMK2D,CBS,CCK,KRIT1,SLC5A11,INA,CBFA2T2,LRBA,LONRF2,KCNAB3,CACNA2D2,ASIC3,CHM,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,SLC24A2,MYL6B,CLTC,ABCG2,COL4A5,CPS1,SLC32A1,CRYM,CNTNAP2,PLCXD3,CX3CR1,HDAC4,DCT,SACS,SV2B,SV2A,DLG3,DLG4,DMPK,SLC12A6,DPP6,DTNB,ABCC9,EDN1,EDN3,EDNRA,SGK2,CACNG7,RASA4,KCNMB2,F5,CACNG3,CACNG2,PTK2B,SLC9B2,FOXM1,ATP2C1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GALR1,ATP8A2,GART,GCK,MSTN,GFAP,GGT7,GGT5,CRCP,DBF4,GLYR1,GLS,OS9,POLL,KCNMB4,RAPGEF4,PLCD4,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1B1,MAP4K5,GYG1,HBA1,HRH3,TNFAIP8L3,HMGCR,HPCA,MYLK2,IGF1,SCIN,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,KHK,MAT2A,AFDN,MTR,MYL3,MYO5A,FXYD7,NBL1,NODAL,NOS1,NPY,NPPA,NPR2,HCN1,NUCB2,OPRL1,P2RX7,P2RY1,KCNK10,PDE3B,ENPP2,GNG2,PENK,PIK3C2A,PIK3CD,PIK3R1,PKD1,PKM,PLCB2,PLCD1,FXYD1,MBOAT7,POU3F4,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,KLK6,PTCH1,RAB3A,RGS4,RGS7,RIT2,MYH14,RPL15,RPS6KA2,KCNIP3,KCNIP2,KCNIP1,RYR1,RYR3,SCN2A,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,IL17RB,SGK1,SCG5,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A7,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC14A1,NAXD,SNAP25,SCN3B,SST,SSTR2,STX1A,ABCC8,PLCB1,SYN2,TAC1,TAC3,TPCN2,SYNE1,CYB561A3,TF,LEFTY2,PIK3R5,RBFOX2,NPL,TRH,TRPC1,KCNE5,SGK3,KCNK12,KCNT2,WNK1,SLC38A1,SCG2,KCNAB1,WNK3,ST8SIA2" Drug ctd:C410127 PCB 180 CTD 8.11E-27 3.97E-22 4.97E-23 5.65E-22 428 1683 "SERPINA3,ABR,ASIC2,ACTN1,FAM43B,ARID1A,CSMD3,DSCAML1,ADCY5,USP31,TEX22,ADRA1B,ADGRF5,SEMA6A,C1QTNF4,SPOP,ARHGAP20,AMH,OGT,CDC42BPA,DPP10,ANK1,ANK3,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,NUMB,TMEM108,ATM,ATP2B2,ATP2B3,N4BP2L1,NOL4,ATP6V1G2,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,MAP7,RUNX1T1,PRC1,CCK,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN1,CHN2,CHRM1,PLEKHB1,LHX2,SLC22A6,DLGAP3,NRXN3,SLC25A27,COX4I1,MFSD4A,NSL1,CLOCK,ENTPD4,SLC32A1,C1QL2,CSF1,ARHGEF10,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,CTNND1,FRMPD4,HDAC4,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,ZEB2,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,NTM,AK5,SGSM2,DLG2,DLG4,DMD,HS3ST2,CDON,SHANK1,DSCAM,DTNA,DTNB,EBF1,USH1C,SNX29,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,PLXNC1,TMEM132E,ELAVL2,PLEKHA1,ENO2,EPB41L1,EPHA5,KCNMB2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,NSRP1,RPS6KC1,CACNG3,PTK2B,ZIC4,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,FGFR3,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FLT1,SMC2,CAMKK2,CELF1,KBTBD12,B3GAT1,TPPP3,NRG3,GAA,GABRA1,GALNT15,GABRG2,GALR1,ZNF274,DISC1,SRRM4,WASF3,TUBA8,CYP46A1,GFRA2,CSDC2,RUNDC3A,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,PSRC1,PRUNE2,B4GALNT4,GPR37,CECR2,CNTRL,GRIA4,RFFL,GRIN1,GRIN2C,NR3C1,ATE1,GRM3,GRM5,ZNF496,RNF165,IL1RAPL1,GSTT2,ZBTB49,BVES,TMEM179,HAS2,HRH3,KLF12,HNF4G,IGFBPL1,DHX35,HTR2A,MYLK2,SOWAHA,IGF1,NKD1,DOCK7,KNDC1,DISP2,HES5,SCRT2,BRINP3,INSM1,LRRTM3,ITPKA,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,MAP6,IL17D,MOBP,MPP2,CPNE9,ADAM22,MSR1,MDGA1,MYCN,MYT1,NASP,RCOR2,NEFH,NELL2,NFIX,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PCDH9,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,KCTD15,ST8SIA5,FXYD1,PURG,NECAB2,PILRA,FAT3,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRN2,TUG1,RAB5B,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,MYH14,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,DRAXIN,SCN2A,SCN4B,SMPD3,ASIC4,IL17RB,MRAS,SCG5,ITSN1,PPM1E,ST6GAL1,SLC1A6,RUFY2,LRRC55,SLC6A8,SLC8A1,SHANK2,SLCO1A2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,FAIM2,UNC80,KIF21B,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,KIF1B,SST,NKAIN2,ADHFE1,AJAP1,ACSBG1,NECAB1,FGD4,SYNE2,VAMP1,PLCB1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,KLHL4,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,VWCE,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TIE1,TIMP4,RELL2,ASXL3,TLR4,TPM1,TPM3,TPM4,DOK6,CHST5,PRMT8,TTC3,TTPA,CLHC1,NSD2,ETNPPL,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,XKR7,NAV2,SLC17A7,TMEM163,SLC17A6,RGS7BP,FAM13C,GJC2,ACTR3B,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:C042720 mercuric bromide CTD 2.12E-26 1.04E-21 1.16E-22 1.32E-21 303 1077 "ASPHD1,ASIC1,ADCY2,SLITRK1,ADCYAP1R1,SORCS1,BEND6,OSBPL6,SEMA6A,ALCAM,PCDH10,ANK1,USP28,PPFIA4,APBA2,EPB41L5,CACHD1,SHTN1,CDC14B,ARRB1,ZBTB10,ASTN1,CCAR2,KIF1A,BCHE,BMP7,SYNJ2,JAZF1,CA4,CACNB2,CALB1,THSD7A,CAMK2D,CARS,MAP7,RUNX1T1,ARHGEF25,CCKBR,SYNGR3,DGKI,REPS2,CDH10,TIGD7,NOG,SYNPR,JAM2,SLIT2,LHX2,RAB33A,NRXN3,TJP2,ABCG2,MAP4K4,FAM149A,TCEAL2,ZNF521,NSL1,HAPLN1,SNCAIP,CSF2RA,FEZ1,LRRC3B,OSBPL3,NCAN,FAM169A,CTH,CTNND2,BOC,RIPOR2,TOX,IST1,DNAJC6,ZEB2,ZBTB24,MFAP3L,SNAP91,CHRDL1,CPEB2,GNE,DTNA,EBF1,EDN1,EDNRB,KLHL5,EFNA2,PLXNC1,TMEM132E,LINC-PINT,LPAR6,SEZ6,EPHB1,NCALD,CEP85L,TMEM74,F3,F5,FAM198B,DLC1,ATP8A1,FECH,SPSB4,FLNC,FLT1,GPR153,CSPG5,MEGF10,GABRA5,GABRB3,JPH4,SALL3,ERAP1,WASF3,SESN1,ADAM28,FREM1,PCDH17,LYVE1,COPS8,GLS,DCLK2,GNAS,LNX1,PRUNE2,GPM6A,GPM6B,DIPK1C,GPR37,ATP2B1-AS1,NR3C1,PRDM5,FAM19A2,FAM222A,UBE2QL1,IGSF21,HRH3,FRMD3,HNMT,SHISA6,CELF5,IDH3A,IFI16,SHISAL1,ZIC5,DOCK7,KNDC1,SCIN,HES5,LIX1,IL6R,ZNF385B,OLFM3,KCNK1,KCNQ2,LAMP2,LIFR,SFXN5,LMO1,NCOA7,LSAMP,CLEC18A,MAP4,MAP6,SYT9,SHC3,KITLG,MITF,MMP16,BCO1,RSPO2,LAYN,NEXMIF,NCAM1,NDP,NEFM,NEFH,NF1,NFE2L2,ALDH1L2,CNOT4,NPY,NPTX1,DDR2,CLDN11,KCNK10,PAX6,PCDH8,PCDH9,PCSK1,PDE3A,PDE4B,PDE4D,SLC10A4,TMOD2,PFKP,GDAP1L1,SERPINI1,RETREG1,PCDH18,POU3F2,PPP1R1A,PPP2R2B,PRKCB,EPDR1,MAPK10,GRAMD1C,RELN,VPS13C,STK32A,PTX3,PEX2,PYGM,TMEM231,ZNF493,RASGRF2,FEZF2,SLC6A15,RET,REV3L,RFX2,RFX4,RGS7,PRIMA1,KLHDC8A,CNTNAP3,AMER2,MIR124-2HG,SCN2A,TNFRSF19,ELMOD1,SOX6,GALNT10,HSPA4L,SGK1,ARX,FHOD3,CNKSR2,SYBU,SLC1A2,PKNOX2,SLC6A8,TMEM132D,COA1,LIMCH1,SNCA,PALLD,SOX1,SOX2,TNIK,LHFPL4,SPP1,CDK19,NFASC,LMO3,COLGALT2,STOX1,SMOC1,SST,EPB41L3,SOX21-AS1,SULF2,AJAP1,ARHGEF9,C3orf70,TMEM150C,TAC1,TACC1,ROBO3,CNTN2,IQCE,KLHL4,NR2F1-AS1,SATB2,TRIM2,SYNE1,DOCK9,SLC35G2,HIF3A,DICER1-AS1,ZMAT3,FAM124A,PIK3R5,RGMB,RUNDC3B,NEIL2,TRPS1,FNDC5,TSC2,SGK3,RPRM,UCHL1,CCDC136,RBFOX3,PCDH20,ZBTB16,CADM2,RGMA,TUBA1A,TMEM163,CAB39L,FAM13C,DOCK8,KAT6A,MSRB3" Drug ctd:C009407 "2,5,2',5'-tetrachlorobiphenyl" CTD 1.66E-25 8.12E-21 8.12E-22 9.24E-21 425 1691 "ABR,ASIC2,ACHE,FAM43B,ARID1A,CSMD3,DSCAML1,ADCY5,USP31,TEX22,ADRA1B,ADGRF5,SEMA6A,C1QTNF4,SPOP,ARHGAP20,AMH,OGT,CDC42BPA,DPP10,ANK1,ANK3,EP400,PPFIA4,CNIH2,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,NUMB,ATM,ATP2B2,ATP2B3,N4BP2L1,NOL4,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,MAP7,RUNX1T1,PRC1,CCK,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,UBE2L6,CHN2,CHRM1,PLEKHB1,LHX2,SLC22A6,NRXN3,SLC25A27,COX4I1,MFSD4A,NSL1,CLOCK,ENTPD4,SLC32A1,C1QL2,RGS6,FEZ2,ARHGEF10,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,ARHGEF4,CTNND1,FRMPD4,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,ZEB2,MFAP3L,MAGI2,TMEM130,LYPD1,ALKBH8,SACS,SPOCK3,NTM,SGSM2,DLG2,DLG4,DMD,HS3ST2,CDON,DNM2,SHANK1,DSCAM,DTNA,DTNB,EBF1,USH1C,SNX29,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,PLXNC1,TMEM132E,ELAVL2,PLEKHA1,ENO2,EPHA5,KCNMB2,APC2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,NSRP1,RPS6KC1,PTK2B,ZIC4,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,ATP5PD,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FLT1,SMC2,CAMKK2,CELF1,KBTBD12,B3GAT1,NRG3,GAA,GABRA1,GALNT15,GABRG2,GALR1,ZNF274,DISC1,SRRM4,WASF3,CPLX1,TUBA8,CYP46A1,GFRA2,CSDC2,RUNDC3A,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,PSRC1,PRUNE2,PRLHR,B4GALNT4,GPR37,CECR2,CNTRL,RFFL,GRIN2C,NR3C1,GRM3,GRM5,ZNF496,RNF165,PTPN5,IL1RAPL1,GSTT2,ZBTB49,BVES,TMEM179,HAS2,HRH3,KLF12,HNF4G,IGFBPL1,DHX35,HTR2A,MYLK2,SOWAHA,NKD1,DOCK7,KNDC1,DISP2,SCRT2,IL12A,BRINP3,INSM1,LRRTM3,ITPKA,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,KIFC3,LSS,MAP6,IL17D,MOBP,MPP2,CPNE9,ADAM22,MSR1,MDGA1,MYCN,MYT1,NASP,RCOR2,NEFH,NELL2,NFIX,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PCDH9,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,KCTD15,ST8SIA5,SMOX,FXYD1,PURG,NECAB2,FAT3,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRN2,TUG1,RAB5B,TMEM255A,ACSS3,SH3TC2,IQSEC3,SUSD4,RET,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,MYH14,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,RYR1,DRAXIN,SCN2A,SCN4B,SMPD3,ASIC4,IL17RB,MRAS,ITSN1,PPM1E,ST6GAL1,SLC1A6,RUFY2,LRRC55,SLC8A1,SHANK2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,FAIM2,UNC80,SPATA7,KIF21B,FNBP1,SOX11,DOK5,NMNAT2,TEX2,ARHGAP26,KIF1B,EPB41L3,NKAIN2,ADHFE1,AJAP1,NECAB1,FGD4,SYNE2,VAMP1,PLCB1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,AP4E1,AKTIP,CDH22,GALNT17,MTMR14,TIE1,TMEM9,TIMP4,RELL2,ASXL3,TPM1,TPM3,TPM4,DOK6,PRMT8,TTC3,TTPA,CLHC1,NSD2,ETNPPL,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,XKR7,NAV2,SLC17A7,TMEM163,SLC17A6,RGS7BP,FAM13C,KAT6A,HNRNPA3,GJC2,ACTR3B,DPF3,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:D020245 p-Chloromercuribenzoic Acid CTD 6.43E-25 3.15E-20 2.87E-21 3.26E-20 263 909 "TTYH1,ASPHD1,ASIC1,SLITRK1,ADCYAP1R1,PLEKHH1,BEND6,SEMA6A,PCDH10,CDC42BPA,ANK1,USP28,PPFIA1,CACHD1,SHTN1,CDC14B,ARRB1,CCDC74A,TMEM108,NOL4,KIF1A,SNAI3-AS1,BCHE,ZNF599,JAZF1,CA4,CACNB2,LURAP1,CALB1,THSD7A,CAMK2D,CARS,MAP7,DGKI,REPS2,NOG,SYNPR,RAB3C,SLIT2,LHX2,RAB33A,NRXN3,CLU,TPP1,ABCG2,FAM149A,SLC4A8,TCEAL2,ZNF521,IGDCC3,NSL1,CREM,HAPLN1,SNCAIP,FEZ1,LRRC3B,NCAN,FAM169A,CTH,CTNND2,ZSCAN23,PYGO1,SPOCK2,ZEB2,MFAP3L,MED24,RABGAP1L,CHRDL1,CALN1,CPEB2,EBF1,KLHL5,PHF20L1,EGFR,PLXNC1,LINC-PINT,TMEM35A,SEZ6,EPHB1,NCALD,CEP85L,TMEM74,F5,ATP8A1,FDFT1,FECH,SYNCRIP,TMEM107,STAMBP,GABRA5,GABRB3,JPH4,SALL3,ERAP1,STARD10,IGSF5,ADAM28,GFRA1,GLS,RAB40B,LNX1,GPM6B,GRM3,PRDM5,IL1RAPL1,GUCY1A2,WIF1,ZHX1,HRH3,FRMD3,ATXN2L,MIER3,HSPA1L,CELF5,EID2B,SHISAL1,ZIC5,DOCK7,PLD5,HES5,LIX1,ZNF385B,OLFM3,KCNJ3,KIF5C,LIFR,SFXN5,LMO1,NCOA7,MAP6,MATK,SYT9,EFHB,MKLN1,BCO1,MT1M,RSPO2,LAYN,NEXMIF,NCAM1,NDP,NEFM,NELL2,NF1,NFE2L2,NPTX1,DDR2,KCNK10,PAX6,PCDH8,PCSK1,SLC10A4,PFKFB2,PIK3C2A,SLC25A23,PCDH18,HMGCLL1,PRRX1,ING3,FAT3,POU3F2,PPP2R2B,PRKCB,EPDR1,GRAMD1C,VPS13C,PXK,PTN,STK32A,PTX3,TMEM231,MARCH1,FEZF2,RET,REV3L,RFX2,RFX4,RGS7,PRIMA1,KLHDC8A,ROBO2,RORB,ARMH4,SPIN3,CNTNAP3,MIR124-2HG,SARS,LRRTM4,SCN7A,SCN8A,TNFRSF19,SOX6,GALNT10,HSPA4L,ARX,CHD9,FHOD3,CNKSR2,BCAN,SLC1A2,DHX30,PKNOX2,LRRC55,SLC6A8,ARHGEF40,TMEM132D,COA1,SMARCE1,PALLD,FAM219A,PDZD2,SOX1,SOX2,SOX5,CLUAP1,SPP1,NFASC,LMO3,COLGALT2,ITPRID2,STOX1,SMOC1,SST,SOX21-AS1,AJAP1,ZFR2,ARHGEF9,C3orf70,EXOC7,CNTN2,NR2F1-AS1,WSCD1,SATB2,SYNE1,PCDHB7,OBSL1,SLC35G2,HIF3A,ZFPM2,ARL10,CBX5,FAM124A,RGMB,RUNDC3B,TRO,TSC2,RPRM,FAM155A,UCHL1,CCDC136,VGF,LMF1,RBFOX3,ZIC1,ZBTB16,SPIRE1,RGMA,TUBA1A,TMEM178A,TMEM163,PCBP4,KAT6A,MSRB3" Drug CID000000119 gamma-aminobutyric acid Stitch 1.39E-24 6.82E-20 5.68E-21 6.47E-20 164 474 "ABAT,ACHE,SLC12A5,ADORA1,ADORA2A,ADORA3,AGT,SEMA6A,AMPH,APOC2,PDXK,ARSE,ASCL1,ALDH7A1,KIF1A,BCS1L,CACNA1I,CACNA1G,BSN,CA4,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALB1,CALB2,HAP1,CCK,CCKBR,CACNA2D2,SOCS6,CHRM1,SYNPR,CHRNA4,CHRNB2,CLCN3,CLCN4,SULT4A1,CNR1,COL4A5,SLC32A1,CX3CR1,DBI,SV2A,DLX1,DMPK,MED12,DRD1,DTNA,EEF1A2,CACNG7,MRO,KCNMB2,GPHN,ERBB4,CACNG2,ZMYND10,PPP1R1B,B3GAT1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GATM,GFAP,GLRB,GLS,GLUL,CNDP1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GABARAPL2,HTR2A,IDH3A,KCNA1,KCNC2,KCNJ3,KCNK3,KCNMA1,MAOB,MAP2,MAPT,MGAT3,NOS1,NPY,NPPA,NTRK2,OGDH,OPRL1,PC,PDYN,PENK,PKD1,GPSM2,PRODH,RELN,APTX,PTCH1,SLC6A15,RGS12,RIT2,RIC8B,RYR1,RYR3,SCN4B,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A9,SLC6A11,SLC12A2,SNAP25,SST,STX1A,VPS13A,SYN1,SYN2,SYP,TAC1,TAC3,TACR1,MLST8,ZEB1,AZIN2,TPM3,TRH,PORCN,ETNPPL,SLC38A1,STMN4,SCG2,SLC17A7,WNK3,SLC17A6" Drug ctd:C081766 "2,4,4'-trichlorobiphenyl" CTD 1.70E-24 8.34E-20 6.41E-21 7.30E-20 371 1437 "ABR,ASIC2,FAM43B,ARID1A,CSMD3,DSCAML1,USP31,TEX22,ADGRF5,SEMA6A,C1QTNF4,SPOP,AMH,OGT,CDC42BPA,DPP10,ANK1,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,ATM,ATP2B2,ATP2B3,NOL4,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,MAP7,PRC1,CCK,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,CHN2,CHRM1,PLEKHB1,SLC22A6,NRXN3,SLC25A27,COX4I1,MFSD4A,NSL1,ENTPD4,SLC32A1,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,CTNND1,FRMPD4,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,NTM,SGSM2,DLG2,DLG4,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,USH1C,SNX29,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,PLXNC1,TMEM132E,ELAVL2,PLEKHA1,ENO2,EPHA5,KCNMB2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,ZIC4,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FOXO3,FLT1,SMC2,CAMKK2,CELF1,KBTBD12,B3GAT1,NRG3,GAA,GABRA1,GALNT15,GABRG2,GALR1,ZNF274,DISC1,SRRM4,WASF3,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,PSRC1,PRUNE2,B4GALNT4,GPR37,CECR2,CNTRL,RFFL,GRIN2C,NR3C1,GRM5,ZNF496,RNF165,IL1RAPL1,GSTT2,ZBTB49,BVES,TMEM179,HAS2,HRH3,KLF12,HNF4G,IGFBPL1,MYLK2,SOWAHA,NKD1,DOCK7,KNDC1,DISP2,SCRT2,BRINP3,INSM1,LRRTM3,ITPKA,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,MAP6,IL17D,MOBP,CPNE9,ADAM22,MSR1,MDGA1,MYCN,MYT1,NASP,RCOR2,NEFH,NELL2,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PCDH9,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,KCTD15,ST8SIA5,FXYD1,NECAB2,FAT3,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRN2,TUG1,RAB5B,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,DRAXIN,SCN2A,SCN4B,SMPD3,ASIC4,IL17RB,ITSN1,PPM1E,ST6GAL1,SLC1A6,RUFY2,LRRC55,SLC8A1,SHANK2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,FAIM2,UNC80,KIF21B,FNBP1,SOX11,NMNAT2,TEX2,ARHGAP26,KIF1B,NKAIN2,ADHFE1,AJAP1,NECAB1,FGD4,SYNE2,VAMP1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,MTMR14,TIE1,TIMP4,RELL2,ASXL3,TPM3,TPM4,DOK6,PRMT8,TTC3,TTPA,CLHC1,NSD2,ETNPPL,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,XKR7,NAV2,TMEM163,SLC17A6,RGS7BP,FAM13C,ACTR3B,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:C009828 "2,4,5,2',5'-pentachlorobiphenyl" CTD 4.76E-23 2.33E-18 1.67E-19 1.90E-18 372 1467 "ABR,ASIC2,FAM43B,ARID1A,CSMD3,DSCAML1,USP31,TEX22,ADGRF5,SEMA6A,C1QTNF4,SPOP,AMH,OGT,CDC42BPA,DPP10,ANK1,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,ATM,ATP2B2,ATP2B3,NOL4,DOCK11,AZGP1,BARD1,RGS9,ARHGEF7,GPC2,CA8,CA12,LURAP1,CALB1,CALB2,KALRN,CAMK2A,CAMK2B,MAP7,PRC1,CCK,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,CHN2,CHRM1,PLEKHB1,SLC22A6,NRXN3,SLC25A27,COX4I1,MFSD4A,NSL1,ENTPD4,SLC32A1,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,CTNND1,FRMPD4,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,NTM,SGSM2,DLG2,DLG4,DMD,HS3ST2,CDON,SHANK1,DTNA,DTNB,EBF1,USH1C,SNX29,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,PLXNC1,TMEM132E,ELAVL2,PLEKHA1,ENO2,EPHA5,KCNMB2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,ZIC4,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FOXO3,FLT1,SMC2,CAMKK2,CELF1,KBTBD12,B3GAT1,NRG3,GAA,GALNT15,GALR1,ZNF274,DISC1,SRRM4,WASF3,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,PSRC1,PRUNE2,B4GALNT4,GPR37,CECR2,CNTRL,RFFL,GRIN2C,NR3C1,GRM5,ZNF496,RNF165,IL1RAPL1,GSTT2,ZBTB49,BVES,TMEM179,HAS2,HRH3,KLF12,HNF4G,IGFBPL1,HSD17B1,MYLK2,SOWAHA,NKD1,DOCK7,KNDC1,DISP2,SCRT2,BRINP3,INSM1,LRRTM3,ITPKA,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,MAP6,IL17D,MOBP,CPNE9,ADAM22,MSR1,MDGA1,MYCN,MYT1,NASP,RCOR2,NEFH,NELL2,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PCDH9,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,KCTD15,ST8SIA5,FXYD1,NECAB2,FAT3,PPP2R2B,LRRN3,VSTM2L,MAPK3,DIRAS2,PSD,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRN2,TUG1,RAB5B,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,RYR1,DRAXIN,SCN2A,SCN4B,SMPD3,ASIC4,IL17RB,ITSN1,PPM1E,ST6GAL1,SLC1A6,RUFY2,LRRC55,SLC8A1,SHANK2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,FAIM2,UNC80,KIF21B,FNBP1,SOX11,NMNAT2,TEX2,ARHGAP26,KIF1B,NKAIN2,ADHFE1,AJAP1,NECAB1,FGD4,SYNE2,VAMP1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,MTMR14,TIE1,TIMP4,RELL2,ASXL3,TLR4,TPM3,TPM4,DOK6,PRMT8,TTC3,TTPA,CLHC1,NSD2,ETNPPL,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,XKR7,NAV2,TMEM163,SLC17A6,RGS7BP,FAM13C,ACTR3B,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:C015001 arsenite CTD 1.83E-21 8.97E-17 5.98E-18 6.81E-17 418 1732 "KCNH8,SYN3,ASIC2,AS3MT,ACTN2,KDM5D,NDRG2,ADCY8,AXIN2,SLC12A5,ERMN,RNF150,ADRA1B,ADRB2,SLC24A4,ZNF608,GPR158,NR0B1,TAOK1,ALAD,SEMA6A,CDC42BPA,ANK2,CNTNAP1,MAGEE2,DGKZ,DGKD,PHYHD1,CACHD1,API5,RGS20,CADPS,ZSCAN18,PCDHGB4,RASL11B,DDX3Y,ATP2B1,ZNF582,ZNF583,BACH1,RGS9,CDK5R1,ST3GAL5,FUBP1,CACNA1D,DDR1,CACNB2,CALM1,KALRN,SYT6,SPAG9,CBLN1,CLDN10,CCK,USP2,INA,AIFM1,CD86,DGKI,CDC25B,CDH2,CDH8,LRRFIP1,LGI1,CDO1,CCPG1,CIART,CHRM1,RAB3C,JAM2,LHX2,NRXN2,TJP2,CNTN1,CABP1,COL9A2,IFFO1,RTTN,MYRIP,ZFP28,FAM171B,CRHBP,SLC32A1,ANKRD44,NCOR2,FEZ1,VCAN,PDE4DIP,SLITRK5,PPP1R16B,ERC2,PLCXD3,CTH,NRSN1,CCDC144A,TOX,RASSF2,LONRF1,MAML1,DAPK1,BRINP1,SIRPA,DNAJC6,ELMO1,MAGI2,KLHL3,GSDME,SNAP91,FAM107B,DLX1,GRIN3A,DMD,DMPK,DNAH9,CALN1,DYNC1I1,DOCK2,DTNA,FAM78B,KRBA2,EBF1,ST8SIA3,EDN1,EEF1A2,SEMA3D,TMTC1,EFNA2,EGFR,EGR3,PLXNC1,EIF4G1,ELAVL2,OLIG2,ENO2,EPB41L1,LRRC17,SEZ6,EPHA5,EPHB1,ERCC2,ANKMY1,CD320,NRN1,ARMCX1,WAC,DLC1,RACK1,CHST15,ZMYND10,SPSB4,FGF12,BAIAP2,CAMSAP1,FOXF2,SYNCRIP,SEMA6C,FOXO3,SEMA4D,SGIP1,FOLH1,NBEA,ERGIC3,DACH2,GABRA4,GABRG2,GAD2,ACSS1,GART,CPLX2,GBX2,GCNT2,PCDH17,GHR,C1QL1,LOXL3,GNAO1,GNAS,GNG4,GPT2,LNX1,GPD2,PRLHR,GPR37,TMEM121B,STMN2,GRIA2,GRIA4,GRIK3,GRIN1,NR3C1,GRM1,GRM7,ZNF496,CIT,CLASRP,FAM19A2,FAM107A,MUM1,IRAK3,HAS2,FRMD3,KLF12,HNMT,ZDHHC15,IGF1,NKD1,RBPJ,IL12A,BRINP3,RIPPLY2,INSM1,LRRTM1,ITGA7,ITGAV,KCNA1,KCNC1,KCNK2,KCNN2,KCNQ2,LAMA2,STMN1,LIFR,VWA5A,MARK1,AQP11,TM6SF1,SHC3,MEIS2,MEST,SCAMP5,MMP17,PTOV1,TAGLN3,RSPO2,MYCN,LAYN,MYT1,NAP1L2,NCAM2,NCF2,NEFM,NELL1,NEUROD1,NFE2L2,ALDH1L2,NKX2-2,NPY,NOVA1,NPTX2,CLEC9A,NTRK3,ODF2,OGG1,OPCML,CLDN11,OXTR,P2RY1,SNTG1,PAK3,PAX6,PCDH8,PCDH9,PCSK1,PCSK2,PDGFRA,PDPK1,PENK,CDK14,SERPINE2,PIK3R1,GPSM2,ST8SIA5,PLXNB3,SPATA6,NXPH1,POU3F4,IRX1,MIR124-2,PKIA,SKOR1,PRKCB,PKN2,MAPK3,MAPK7,MAPK8,MAPK9,MAPK10,PROX1,PRPH,RELN,LAMA1,PTCH1,PTHLH,ELOVL2,ZIK1,PTPRE,PTPRG,PTPRZ1,PTX3,PYGM,TMEM255A,ACSS3,RAP1GAP,RASGRF2,DBX2,FEZF2,RGS3,RIT2,RNF220,PNMA8A,RORB,TMEM100,EPHA10,RPL38,SYNDIG1,SALL1,SEMA6D,LRFN5,SCN2B,SCN7A,FNIP1,SFPQ,HSPA4L,NLGN4Y,SH3GL3,ARX,SLITRK3,BCAN,TRIM67,ZNF334,NAPB,ZNF667,GKAP1,SORCS3,SNAP25,SNCB,MAPKBP1,SNCA,PDZRN3,SOX2,SOX3,TNIK,SOX5,SOX11,DOK5,NMNAT2,ENKUR,DBNDD2,LMO3,SRPK2,SMOC1,SST,SSTR1,MAPK8IP3,PLCB1,SYT1,TAC1,TACR1,ANKRD12,TAL1,TBCEL,ANO4,TBX15,PCDHGB7,PCDHGB6,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,PCDHB7,PCDHB6,PCDHAC2,PCDHA3,TF,SIRT1,CHST8,THBS4,GALNT17,TIAM1,ICAM5,TLR4,ZFP91,NR2E1,TMPO,TNFRSF1B,PARD3,TNNT1,PIK3R5,TPD52L2,PDSS1,TRO,TMEFF2,RPRM,UCHL1,UGT8,FLRT2,MGAT5B,VLDLR,VSNL1,ZNF781,ZIC1,KCNT2,NDRG4,LYPD6,TCEAL7,CELF4,ZNF154,LAMP5,CA10,PRTFDC1,STMN4,PRDM8,VPS35L,SLC17A6,DOCK8,FRMD6,NETO1,ST8SIA2" Drug ctd:C038939 enzacamene CTD 2.31E-21 1.13E-16 6.90E-18 7.85E-17 67 130 "ABAT,ACTN1,UNC5A,CASK,NCOA1,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CAMK2B,SYT6,CACNA2D2,DLGAP3,NRXN1,NRXN2,DCC,MAGI2,CHRDL1,DLG4,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,CACNG2,FGFR1,FYN,GABRA4,GABRB1,GLS,STMN2,GRIA2,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,IL1RAPL1,NXPH3,NF1,NRCAM,NTRK2,NTRK3,CNTN3,RELN,MDGA2,ROBO1,STX1B,HES6,NLGN1,SLC1A2,SLC1A3,SLC1A6,SHANK2,SLIT1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug CID000020382 tetradotoxin Stitch 2.39E-21 1.17E-16 6.90E-18 7.85E-17 146 428 "ASIC1,ACHE,ADCYAP1R1,SLC12A5,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,KIDINS220,ANK3,PHF12,ATP1A1,ATP1A2,ATP1A3,ATP1B3,BCHE,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALB1,CCK,CCKBR,INA,P2RX6,ASIC3,CHRM1,CHRNA4,CHRNB2,CNR1,COX4I1,BOC,BLOC1S6,DMPK,DRD1,EDN1,EDN3,EDNRA,EDNRB,KCNMB2,PTK2B,FOXM1,B3GAT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,NKX6-2,GALR1,INPP5K,CRCP,GLRB,POLL,KCNMB4,LPAR4,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1B1,HRH3,HTR2A,HTR5A,KCNA1,KCNA2,KCNA4,KCNA6,KCND2,KCND3,KCNK3,KCNMA1,KCNN1,KCNN3,MTR,P2RY13,NOS1,NPY,NPPA,NPR2,HCN1,OPRL1,P2RX7,P2RY1,PDCD2,ENPP2,PDYN,PENK,GPSM2,PRKCB,PRKCG,PKN2,PRKCZ,EPDR1,PTCH1,RIT2,S100B,SCN2A,SCN3A,SCN4B,SCN7A,SCN8A,SCNN1D,ASIC4,SLC6A1,SLC6A11,SCN3B,SST,SYN2,SYP,TAC1,TAC3,TACR1,AKTIP,TRH,NTSR2,VIPR2,P2RY12,ST8SIA2" Drug ctd:C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester CTD 4.22E-21 2.07E-16 1.15E-17 1.31E-16 231 810 "SERPINA3,AS3MT,CCDC85A,AXIN2,GRAMD1B,ADORA1,ADRB2,ZNF608,PCDH19,OSBPL1A,NME5,OSBPL6,SORCS2,C1QTNF1,C1QTNF3,ALAD,SEMA6A,BCAR3,ARHGAP20,ANK3,LCORL,APBB2,ALS2,SFMBT2,PRX,ARNTL,CAPRIN2,DACT3,RASL11B,ATP1B3,ATP6V0A1,DOCK11,ADAM23,NRP2,GPR146,BMPR1B,ST3GAL5,CACNA1G,BSN,IL33,CAMK2G,VSTM2A,CH25H,CBR1,USP2,MTMR7,P2RX6,CD86,CD38,DCLK1,ADGRG1,CBARP,SYNPR,FAM189A2,PCYT1B,SLC4A7,ZFP28,NECTIN3,ANKRD44,NCOR1,SNCAIP,CSF1,MICAL2,VCAN,SOCS5,PLXNA4,CTH,HDAC9,GPRASP1,RASSF2,DAPK1,SPOCK2,PITPNC1,ELMO1,MFAP3L,RUSC2,MED24,LYPD1,GSDME,SV2A,TMCC2,KBTBD11,DLG2,DLX1,DYNC1I1,CDON,CPEB2,SLC12A6,DUSP9,EDN1,SEMA3D,EFNA2,KMT5B,EGR3,SORBS3,RGS17,ECSIT,HSPA12B,TBC1D16,ST3GAL6,FER,OLFM1,FGFR1,MEX3B,FLT1,PDLIM5,NSG2,GPR153,STAU2,MEGF10,GAB1,GALNT15,RAPGEF6,MTHFD2,CSDC2,GGT5,GHR,MALT1,GLUL,AIFM3,TDRKH,GPR19,NR3C1,SLC2A6,MAP4K5,NXPH3,HLF,IGF1,NKD1,GAREM2,DISP2,IL6R,JAK1,KCNH1,KCNK2,KTN1,HECTD2,FGFBP3,GPR155,MBP,SRSF12,PPM1L,AFDN,MMP17,MPP2,RSPO2,MYCN,MYO7A,RTL5,NBL1,NFE2L2,DDR2,PAK3,SERPINI1,KCTD15,PLCL1,PCDH18,NXPH1,PPP2R2B,PPP3CC,PKIA,DIRAS2,MASP1,PTPRB,PTPRZ1,PTX3,PEX2,FAT4,FIGN,TTLL7,SEC61A2,KLHDC8A,CLIP1,ATXN1,TNFRSF19,SMPD3,GALNT10,HSPA4L,DOCK10,MAGI3,ST8SIA1,SLC1A2,SLC1A3,SMTN,SLC6A9,SLC12A2,SLC14A1,SLC22A4,SNCA,MBD5,PDZD2,TNIK,SOX11,NMNAT2,CAND2,HECW1,ITPRID2,SMOC1,EPB41L3,LRRC4,SYNE2,RHBDL3,VPS13A,PLCB1,COBL,TAC1,WWC1,TPCN2,PSD3,FRYL,ZFPM2,TIAM1,CBX5,TNFRSF1B,NPL,TRPS1,SSBP2,AMOT,PLEKHH2,VGF,VLDLR,NSD2,CLDND1,TMEM237,DPYSL5,ADAMTS9,PCBP4,FBXO36,TTC7A,NETO2,SPATA13" Drug ctd:D006220 Haloperidol CTD 4.49E-21 2.20E-16 1.16E-17 1.32E-16 125 344 "DPF1,SERPINA3,ADCY5,AXIN2,ADORA2A,AP2A2,OSBPL8,ATP1A1,ATP1A3,ATP1B3,RGS9,CACNA1A,CAMK2A,CAMK2B,CAMK2D,CCK,CDC42,DCLK1,NUMBL,CHN1,CHRM4,RAB28,CLTA,CLTB,ABCG2,QKI,CRHBP,NCAN,CST3,DRD1,DRP2,EDN1,RASGRP1,ERBB2,ERBB4,PPP1R1B,HPCAL4,SYT3,CAMKK2,FYN,GABRA1,CHL1,GABRB3,GAD1,GAD2,GLUL,PCSK1N,GNAS,MCHR1,RAPGEF4,GRIA1,GRIA2,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,HMGCR,HTR2A,KCNA1,KCNH2,KLC1,MAG,MAOB,MAP2,MBP,MOG,NPY,NPPA,NPTX2,OPRL1,CLDN11,PDE4A,PDE1B,PENK,PFKP,ABCB1,SERPINI1,PKM,PLP1,PPM1B,PPP1R1A,PPP3CA,PPP5C,PRKACB,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,RELN,WBP1L,RASGRF1,RGS4,RORB,KCNIP3,STX1B,RXRG,SGK1,SLC1A2,SLC1A3,RIMS1,SNAP25,TNIK,STX1A,SYT11,VAMP1,ARC,SYN2,SYPL1,SYT4,TAC1,TRIM2,TF,THRA,UGT8,VLDLR,VSNL1,MAP3K12,KCNAB1,SLC17A6,RTN4" Drug ctd:C013418 bromfenacoum CTD 2.73E-20 1.34E-15 6.64E-17 7.55E-16 193 645 "ABAT,ACLY,SLC25A25,ADD1,ERMN,CASKIN1,AGT,SORCS2,ALCAM,ANK3,SEMA7A,PKP4,ANXA7,CNTNAP1,APBB1,APC,GAS7,ATP1A3,ATP2A2,ATP2B2,ALDH7A1,ATP6V0A1,DST,BSN,WASF1,CACNA2D1,CALB1,CALB2,CALM1,CANX,CAST,CBS,INA,AIFM1,LGI1,CPNE6,HECTD1,HOMER3,CNN3,PICK1,CNTN1,HAPLN1,SLC32A1,CS,ARHGEF10,VCAN,FAM169A,PNPLA8,CTNND1,CTNND2,RIMS2,FAM131B,SNPH,MATR3,SCRN1,SPOCK2,DBI,DNAJC6,HP1BP3,MTX3,FAM107B,SEC16A,DLG4,ABI1,PDCD6IP,FIS1,EEF1D,RBM12,SUGP2,C8orf37,EIF1,EPB41L1,MTSS1L,RTN3,FABP7,RACK1,BAIAP2,VTI1B,SGIP1,SPECC1,PDLIM5,ARFGAP2,ATP2C1,PRELID3A,ABLIM2,ZNF512,GAB1,CAB39,GAD2,HBS1L,GAP43,ALDH1L1,GFAP,TCERG1,RNPS1,GLDC,MAP7D2,TDRKH,NUDT21,STMN2,TPPP,RAPGEF1,DIDO1,GRIA4,PSIP1,PADI2,ATXN2L,HNRNPK,AGFG1,IDH3A,SLC6A17,ITPKB,KIF5C,KLC1,VWA5A,MAOB,MAP4,MAP6,MOG,DBNL,CTNNA3,NACA,NAP1L1,NEFH,NOS1,OPA1,OPHN1,PALM,PDE4D,OLA1,PLCD1,PLXNB1,RELN,CNNM2,UHRF1BP1,ATG16L1,RAP1GAP,ROGDI,ZYG11B,RNH1,MYH14,ELP2,SGSM1,MAP6D1,RTN1,NCBP3,FAM192A,ATXN2,SFPQ,HSPA4L,KIF21A,PPP1R9A,SH3GL2,CPEB3,SHMT2,CCDC92,SLC1A3,EPN2,SLC8A2,SLC12A2,NAPB,NAXD,LIMCH1,SNCB,TNIK,SPTAN1,MPRIP,STXBP1,MLC1,SYN1,SYT1,KAZN,CAMSAP2,CNTN2,CRTC1,AHCYL2,SIK3,TJP1,TNR,TST,HEPACAM,FRRS1L,OSBP2,CCDC136,TOM1L2,VSNL1,SPHK2,FIP1L1,C12orf4,RTN4,NHSL1,FXR1,SLC4A10" Drug ctd:C014024 "2,4,5,2',4',5'-hexachlorobiphenyl" CTD 2.84E-20 1.39E-15 6.64E-17 7.55E-16 433 1835 "ABR,ASIC2,TKTL1,FAM43B,ARID1A,CSMD3,DSCAML1,AXIN2,FZD9,USP31,TEX22,PLA2G6,ADGRF5,SEMA6A,C1QTNF4,SPOP,ALCAM,AMH,OGT,CDC42BPA,DPP10,ANK1,EP400,PPFIA4,KCNAB2,EPB41L5,GAS7,ALS2,AMER3,PPFIA3,APP,PRX,PDXK,CADPS,ASPA,CCDC74A,ASPH,PTCH2,ZBTB10,ATM,ATP2B2,ATP2B3,NOL4,DOCK11,AZGP1,BARD1,RGS9,LDHD,ARHGEF7,AP1M1,GPC2,IL33,CA8,CA12,LURAP1,CALB1,CALB2,CALM1,KALRN,CAMK2A,CAMK2B,MAP7,PRC1,CLDN10,CCK,NEURL1,LRBA,CDC25B,CDH8,CDH18,L3MBTL4,MAGI1,CRLF1,CHN2,CHRM1,PLEKHB1,SLC22A6,NRXN3,SLC25A27,COX4I1,MFSD4A,NSL1,CLOCK,ENTPD4,AKAP12,SLC32A1,CSF1,MICAL2,IPCEF1,PLCH2,PDE4DIP,CNTNAP2,CST3,CALY,PLCXD3,GREB1,CTNND1,CYBB,FRMPD4,PHYHIP,DGKG,DAPK1,DBN1,DNAJC6,MFAP3L,TMEM130,LYPD1,SACS,SPOCK3,NTM,SGSM2,DLG2,DLG4,DMD,HS3ST2,CDON,SHANK1,CASP8AP2,DTNA,DTNB,DUSP9,EBF1,USH1C,SNX29,RASGRP1,FRY,CACNG7,EFNA3,CELSR3,PHF20L1,EGFR,PLXNC1,TMEM132E,ELAVL2,PLEKHA1,ENO2,EPHA5,KCNMB2,ETV1,DNAJC27,SIRPB1,CD320,MRVI1,RPS6KC1,PTK2B,ZIC4,TUBB3,SCML2,FCGR1A,CHST15,ZSCAN30,PPP1R1B,FGF1,FGF12,FGF14,MEX3B,HPCAL4,CAP2,AGAP2,ZMYND15,FOXM1,FOXO3,FLT1,SMC2,CAMKK2,CELF1,KBTBD12,B3GAT1,NRG3,GAA,GAB1,GABRA1,GALNT15,GABRG2,GALR1,ZNF274,DISC1,SRRM4,WASF3,TUBA8,CYP46A1,GFRA2,CSDC2,BRD8,DBF4,SPIN1,GLI2,GPR75,GLS,TOX3,GLUL,PCDH11X,MAP7D2,INSM2,PCSK1N,GNAL,PSRC1,GPD2,PRUNE2,B4GALNT4,GPR37,CECR2,CNTRL,RFFL,GRIN2C,NR3C1,GRM3,GRM5,ZNF496,RNF165,IL1RAPL1,GSTT2,ZBTB49,BVES,TMEM179,HAS2,HRH3,KLF12,HMGCR,HNF4G,IGFBPL1,HSD17B1,IRF8,MYLK2,SOWAHA,IGF1,NKD1,DOCK7,KNDC1,DISP2,HES5,SCRT2,BRINP3,INSM1,LRRTM3,ITGA7,ITPKA,JAK1,KCND2,KCND3,KCNMA1,KCNQ2,KIF5A,STMN1,LIFR,MAOB,MAP6,MDFI,IL17D,MEIS1,SCAMP5,MOBP,CPNE9,ADAM22,MSR1,MT1M,MDGA1,MX1,MYCN,MYT1,NASP,RCOR2,NEFH,NELL2,NFIA,NFYA,NHLH1,NME4,NOVA1,NPTX1,DDR2,KSR2,GPR88,OMG,OPCML,GPR137C,SNTG1,PBX1,PCDH9,CDK18,PRTG,PDE1C,PDE4B,PDGFRA,ENPP2,PENK,PFKP,ABCB1,NALCN,TMEM38A,KCTD15,ST8SIA5,FXYD1,PSAT1,NECAB2,FAT3,PPARA,PPP2R2B,LRRN3,VSTM2L,MAPK3,MAPK8,DIRAS2,PSD,SNRK,CNTLN,PLPPR1,UHRF1BP1,SPDL1,PTPRD,PTPRN2,PEX2,TUG1,RAB5B,TMEM255A,ACSS3,IQSEC3,SUSD4,RET,ERI2,RFX5,TTLL7,RIT2,PBRM1,ZFHX4,KIRREL1,ROBO2,MRAP2,PLPPR3,HUNK,ST6GALNAC6,STX1B,DRAXIN,SCN2A,SCN4B,TNFRSF19,SMPD3,ASIC4,IL17RB,SCG5,ITSN1,PPM1E,HKDC1,ST6GAL1,ABLIM3,SLC1A3,SLC1A6,RUFY2,LRRC55,SLC8A1,SLC8A3,SHANK2,ARFGAP1,OGDHL,RCOR3,IGSF9B,RIMS1,FAIM2,UNC80,KIF21B,FNBP1,SOX11,NMNAT2,SPP1,TEX2,UNC5B,ARHGAP26,KIF1B,MESP1,SST,NKAIN2,ADHFE1,AJAP1,NECAB1,FGD4,SYNE2,VAMP1,SYP,TAC1,POPDC3,ANKRD12,MCF2L,PDLIM2,CNTN2,ACSL6,SATB2,ZEB1,RALYL,PSD3,GPRIN3,FRYL,AP4E1,CDH22,GALNT17,THRA,MTMR14,TIE1,TIMP4,RELL2,TJP1,ASXL3,TLR4,TPM3,TPM4,DOK6,PRMT8,TTC3,TTPA,TUB,CLHC1,NSD2,SLC13A3,ETNPPL,KCNK12,ZNF184,PROCA1,ANKS1B,FTSJ1,GDPD5,PRDM8,XKR7,TUBA1A,NAV2,TMEM163,SLC17A6,RGS7BP,FAM13C,ACTR3B,AP3B2,ST8SIA2,SLC4A10,SPATA13,JPH3" Drug ctd:D007649 Ketamine CTD 6.81E-20 3.34E-15 1.52E-16 1.73E-15 226 803 "NDRG2,GALNT16,CCDC85A,ADCY8,ADD2,SORCS1,PTCHD1,AGT,TMEFF1,SPTBN4,ARHGAP5,ASCL1,BRINP2,RASL11B,ATP1A1,ATP1A2,ATP1A3,NOL4,ATP6V0A1,DOCK11,ADGRB2,RGS9,BCS1L,FUBP1,SCAPER,C1QC,MMD2,CA4,CALB2,CABP7,HAP1,USP2,INA,P2RX6,CD38,CCPG1,GPR37L1,CHRM1,PLEKHB1,ZBED5,CLU,FAM189A2,RAB26,CNR1,ACBD5,HS3ST5,NECTIN3,SLC32A1,ABCG1,VCAN,SOCS5,PHACTR3,CMTM5,PHF14,PLCXD3,CYBB,EARS2,RASSF2,PHYHIP,C2CD2L,DNM1,DMTF1,FEM1B,EFNA2,ENO2,ERBB4,TMEM74,EZH1,CACNG2,FDFT1,PPP1R1B,FGFR3,BAIAP2,PRKAG2,SCARA3,ATP13A4,GABRA5,GABRG2,GAD1,FAM120B,NKX6-2,FAXC,CYP46A1,SESN1,GFAP,RUNDC3A,CRCP,GLUL,ZNF638,CBX1,GPR22,TUBA1C,PLCD4,GRIK5,GRIN1,GRIN2C,GRM3,MFSD2A,GUCY1B1,SLC2A6,MUM1,HRH3,HMGCR,IGFBPL1,HPCA,CFAP126,IGFBP1,HES5,IL12A,DIPK1A,ITPKA,JAK2,KCNC2,KTN1,PIK3AP1,MAP6,MAPT,MATK,MBP,EFHB,MOG,COMMD5,TAGLN3,MYCN,FXYD7,SLCO1C1,NPY,NOVA2,NRGN,NTRK2,CLDN11,TREM2,PCSK2,ENPP2,GPR85,CDK14,ABCB1,GDAP1L1,PKD1,PLCL1,SMOX,PLP1,HMGCLL1,ASPDH,SEPT4,FAT3,POLG,POLR2F,POU3F2,CRLS1,PRKCG,MAPK3,MAPK7,SYTL2,PLPPR1,PTK2,PTPRH,PTPRN,PYGM,FAT4,RASGRF1,RBBP6,RBBP8,CRTAC1,TTLL7,ZFHX4,RTKN,YJEFN3,KCNIP2,RXRG,S100B,SCN4B,FAM19A1,HES6,ASIC4,SFPQ,MRAS,SLC1A2,SLC2A5,WDR47,LRRC55,MTERF2,SLC20A2,CXXC4,CABCOCO1,SOX11,CAND2,HECW1,SSTR1,ST5,NCDN,ACSBG1,KLHL7,VPS13A,TAC3,KAZN,SATB2,TF,ICAM5,TLR4,TMPO,TNNT1,RASD2,TPM1,TPM4,METTL3,TRH,ZMYND8,TMEFF2,CLEC2L,PDIA2,MICAL1,WRN,LGI4,POLR3H,LAMP5,INTS3,NAV3,SLC17A7,ITM2C,PLD4,PAK5,JMJD1C,SLC39A12,KLHDC1,SENP7" Drug ctd:C118580 octylmethoxycinnamate CTD 8.01E-20 3.92E-15 1.71E-16 1.94E-15 68 140 "ABAT,ACTN1,UNC5A,CASK,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CAMK2B,SYT6,CACNA2D2,DLGAP3,NRXN1,NRXN2,DCC,MAGI2,CHRDL1,DLG4,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,CACNG2,FGFR1,FYN,GABRA4,GABRB1,GLS,STMN2,GRIA2,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,IL1RAPL1,NXPH3,IGF1,NF1,NRCAM,NTRK2,NTRK3,OGG1,CNTN3,RELN,MDGA2,ROBO1,STX1B,HES6,NLGN1,SLC1A2,SLC1A3,SLC1A6,SHANK2,SLIT1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug ctd:C030370 "2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone" CTD 1.47E-19 7.22E-15 2.94E-16 3.35E-15 116 320 "RALGAPA1,NDRG2,BBOX1,BIN1,ANK2,APP,CASK,MARK4,ATP1B3,MYRF,CALM1,CBR1,CDC42,CHGA,PLEKHB1,NRXN1,NRXN2,CLU,TPP1,CLTB,QKI,CNTN1,COL9A2,RBM39,LRIG1,CNTNAP2,SLITRK5,CTNND2,DOCK4,MATR3,DBI,YTHDC1,SV2A,SEZ6L2,EEF1D,APH1A,GOLGA7,EPB41L1,TUBA1B,TUBB3,TUBB4A,EFEMP1,PRKAG2,EVL,CSPG5,GABRA4,GAD2,AHCYL1,GATM,GFAP,GLUL,PRUNE2,GPR37,TUBA1C,STMN2,GSTM5,GUCY1B1,HBA1,SCRG1,HNRNPK,HPCA,HSP90AA1,IDH3B,TUBB2B,KCNQ2,KIF5C,MAG,MEF2C,CD200,MRPL42,NEFM,NOVA1,NTRK2,NTRK3,OPCML,PAK3,PCDH8,PCDH9,PFKFB3,SERPINI1,PPP2R5E,PRKACB,PRKCB,PTN,QDPR,RALGDS,CHD9,RPH3A,SNAP25,SNCA,DOK5,SPP1,KIF1B,LMO3,CLASP2,ITPRID2,EPB41L3,MAPK8IP3,SEPT8,PLCB1,SYPL1,SYT1,TAC1,CAMSAP2,TF,HEY1,RBFOX2,TPD52,TUBB2A,UBC,UCHL1,CLIP2,ETNPPL,ZIC1,ZBTB16,RTN4" Drug ctd:D013759 Dronabinol CTD 1.50E-19 7.36E-15 2.94E-16 3.35E-15 247 908 "ACTN2,TMCC3,ADORA2A,HECW2,CASKIN1,KCTD16,TAOK1,SPARCL1,ALCAM,ALK,PPFIA2,APBB1,BCAS1,SHROOM2,AQP4,CDC14B,SPTBN4,ARHGDIA,ASGR1,ASPA,KIF1A,BCL2L2,IL33,CA8,CALB1,CALB2,HAP1,CAMK2A,CAMK2B,CARS,HIP1R,SPAG9,CBLN1,CCK,RGN,NEURL1,CDC42,LRRFIP1,LGI1,UBE2L6,COPB2,FOXN3,PLEKHB1,RAB3C,KMT2C,CPNE6,NRXN3,NRXN1,MYL6B,LY86,CNR1,SLC4A7,MFSD4A,CRMP1,AATK,FAM169A,CMTM5,CENPL,DCC,NTM,AK5,RABGAP1L,SEC16A,DLG4,OLIG1,USP3,NR1D2,DRD1,ST8SIA3,WDPCP,EDNRA,PHF20L1,EGR3,EIF4G1,EIF5,COPS4,DCTN4,ERBB4,EFS,SPEG,RTN3,NRN1,FABP7,ACSL4,TUBB4A,FGF1,OLFM1,HPCAL4,CAP2,FOXM1,NSG2,NSG1,ADGRA1,FYN,GABRG2,GALC,ARPP21,MTHFD2,GCK,GCNT2,SESN1,GFAP,CSDC2,CBX1,DCLK2,GNAO1,GPT2,GOLGB1,TUBA1C,GRIA1,PLCD4,GRIK1,GRIK3,GRM5,FAM107A,GUCY1A1,SLC2A6,NXPH3,HNRNPK,HPCA,HP,OPALIN,HSPA1L,HSP90AA1,SOWAHA,IGF1,IGSF1,IL12A,ITPKA,KCNA1,KCNMA1,L1CAM,LIG4,MAOB,MAP2,MAP6,MAT2A,MBP,SYT9,MOBP,TAGLN3,MYH3,FXYD7,NCAM1,NEFH,NEUROD2,NOS1,SLC11A2,NTRK2,DDR2,NUCB2,GPR88,OPCML,OPRL1,CLDN11,PAK3,PDYN,PENK,ABCB1,SERPINE2,PKM,PLP1,FA2H,PPARA,PPP2R5C,PPP3CB,PKN2,MAPK3,MAPK8,MAPK9,KLK6,CNNM2,VPS13C,LAMA1,PTN,PTPRE,PTPRN,RALGDS,RASGRF1,VEPH1,SLC6A15,CRTAC1,ZYG11B,SLC25A36,YY1AP1,KCNIP3,KCNIP2,RXRA,RYR1,S100B,SARS,ATXN1,SCN8A,FNIP1,PUF60,SGK1,NTNG1,SHMT2,SEC31A,ABLIM3,RPH3A,SLC6A1,SLC6A7,SLC6A9,NAPB,SLC15A2,EFHD1,CPEB4,MAST1,FAM126B,SOX15,ZC3H13,CDK19,SEPT8,PHLDB1,SYT11,MLC1,PRRC2C,ARC,TAC1,ANKRD12,DNMBP,PDLIM2,ACSL6,SYNE1,PCDHA1,TF,DNAH7,TPD52,TPD52L2,TRPC1,TTC3,PRR18,TMEFF2,UBC,UGT8,CCDC136,ZIC1,NDRG4,TFIP11,PMEPA1,SCG2,SNX27,TMEM163,SLC17A6,RTN4,GJC2" Drug 4770_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.68E-19 1.31E-14 5.04E-16 5.74E-15 78 177 "DPF1,ADD3,NME5,APC,MARK4,N4BP2L1,ST3GAL5,CACNA1G,BAIAP3,CDK5R2,BTRC,CDH18,CLGN,PDE4DIP,SEC14L5,KIAA0513,RIMS3,CTIF,ARMCX2,DNAJC6,SRGAP3,TMCC2,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,STX2,TUBB4A,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,PCLO,KCND3,KIF5C,MPP2,MXI1,NOVA2,NPTX1,SERPINI1,PIK3CD,PRPH,LRRC49,RAB3A,TTLL7,NUDT11,SATB1,SH3GL3,FRMPD1,ASAP3,ST6GAL1,SYBU,WDR47,PKNOX2,CCDC88A,SMARCD3,ZCCHC24,KIF21B,SOX15,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,EXOC7,HEY1,TNS1,RUNDC3B,DNAJC12,BEST1,NDRG4,SLC30A3,SLC17A7,PLSCR4" Drug ctd:D000726 Androgen Antagonists CTD 3.65E-19 1.79E-14 6.63E-16 7.54E-15 46 75 "ACTN1,CASK,CACNA1I,CACNA1G,BSN,CACNA1D,CACNA2D1,CACNB2,CAMK2B,SYT6,CACNA2D2,DLGAP3,NRXN1,NRXN2,DCC,MAGI2,DLG4,SHANK1,ERBB2,ERBB4,GABRA4,GABRB1,GLS,GRIA2,GRIA4,GRIK2,GRIN1,GRIN2D,IL1RAPL1,NF1,NRCAM,NTRK2,NTRK3,CNTN3,RELN,MDGA2,ROBO1,HES6,NLGN1,SLC1A3,SLC1A6,SHANK2,STXBP1,TSC2,VLDLR,SLC17A7" Drug CID000161645 oriens Stitch 4.99E-19 2.44E-14 8.73E-16 9.93E-15 71 154 "ACHE,ACTN1,ADORA1,ADORA2A,CA4,CALB1,CALB2,CCK,CHRM1,SYNPR,CHRNA4,SLC32A1,NCAN,PDCD6IP,DPYSL4,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GAP43,GFAP,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,SYNPO,KCNA6,KCNC1,KCNC2,KCNJ9,KCNK3,KCNQ3,LSAMP,MAP2,NPY,NTRK2,NTRK3,PENK,PRKCG,RELN,PTPRZ1,RAB3A,RGS7,BCAN,SLC6A1,SLC8A2,SNAP25,SST,SYN1,ARC,SYN2,SYP,HHIP,VSNL1,SLC17A7,NUP214" Drug ctd:D008694 Methamphetamine CTD 6.80E-19 3.33E-14 1.15E-15 1.31E-14 345 1407 "RALGAPA1,ARID1A,SLC25A25,NDRG3,PLEKHG5,ADCY6,ADD2,ADORA1,ADORA2A,ADORA3,ADRA1B,AP1B1,ADGRF5,SRPX,CARNS1,LTBP4,AMPD3,BIN1,EP400,DGKZ,CDK10,PDXK,ARHGDIA,ARRB2,ATP1A1,ATP2A2,ATP6V0A1,MYOM1,TTLL9,ADAM15,BARD1,BCL2L2,BID,PROM1,LDHD,DST,SYNJ2,BAIAP3,CA4,CACNA2D1,CACNB4,LURAP1,CALB2,SPAG9,ARHGEF25,CBR1,CCK,P2RX6,ARHGEF1,ARHGEF2,LRRFIP1,LARGE1,MAGI1,DIS3L,ASIC3,TAOK2,NDST3,ABCG2,FAM19A5,DNAJB5,CNR1,PICK1,CNTFR,C2CD2,CREM,ANKRD44,NCOR2,GDA,CRYM,CS,CSF1,ARHGEF10,PDE4DIP,PUM1,RIMS2,PPP6R2,GPSM1,CX3CR1,CYBB,HDAC9,RIPOR2,ZFYVE16,LIN54,IST1,DGKG,IP6K1,LYPD1,ZC3H11A,AK5,ARNT2,DMD,DNM1,HS3ST4,DMPK,FAM57B,DPYSL2,DRD1,USH1C,RASGRP1,SIDT2,EBI3,RASA4,EIF4G2,RGS17,SRPK3,PCOLCE2,USPL1,PLEKHO1,ENO2,MFSD10,EPB41L1,RASGRP2,ENPP6,SRRM1,NCALD,SPEG,HSPA12B,F3,FABP7,SH3YL1,TUBA1B,STRADA,PPP1R1B,FGFR3,ATP5PD,FLNC,FLT1,SYT3,TACC2,SORBS1,FYN,GABRA1,GABRG2,GAD2,NKX6-2,GAP43,MTHFD2,SYT17,CPLX2,CPLX1,WASHC2A,GFAP,GFRA2,C1QL1,PPARGC1A,RAB30,GLS,TNRC6A,ZNF638,CBX1,POLL,GOLGB1,PRUNE2,GPR17,GPR19,GRIA1,GRIA2,SPACA9,GRIN1,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,PTPN5,NXPH3,ATXN2L,BACH2,SCRG1,GABARAPL2,AGBL5,HPCA,HSP90AA1,HTR2A,IDH3A,KNDC1,TJAP1,HES5,SCRT2,DIPK1A,RIPPLY2,KCNB1,CLVS2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,LAMP2,STMN1,PIK3AP1,MAOB,MAP2,MAP4,MAPT,MBP,SYT9,MIA2,MN1,MOV10,COL28A1,NRBP2,MT3,TAGLN3,LYRM9,MYH6,MYH7,MYO7A,MYT1,NDUFA5,IDNK,NFE2L2,NOS1,NPY,NPTX2,OGG1,OPRL1,OXTR,TREM2,PCMT1,PCSK1,PDE2A,PDE4B,PDE4D,PDE1B,PDGFRA,PDYN,PENK,PFKFB2,ABCB1,PHKG1,PIK3R1,XRN1,PKM,PLCD1,PLEC,SMOX,ANKRD16,PSAT1,PILRA,PACSIN1,MINDY2,PPP3CA,PPP3CB,PRODH,GON4L,SNRK,PTH1R,RAD52,RGS4,RPL15,PRR5L,LGR4,CLIP1,SBF1,SEC14L1,SGK1,PPP1R9A,SH3GL2,CPEB3,MYO18A,FUZ,SLC1A2,SLC1A3,SLC4A3,SLC2A5,LIMS2,SLC6A8,SLC6A9,SIRT2,TRIM67,LGI3,ZFP1,OGDHL,SORCS3,SMARCD3,SNCB,SNCA,PALLD,FAM126B,SPTAN1,CAMTA2,ITPRID2,THSD1,SSTR2,MAPK8IP3,MPRIP,PHLDB1,SEPT3,AJAP1,NECAB1,JMJD6,SUPT5H,PRRC2C,ARC,SYN2,SYP,ASTN2,TAC1,EXOC7,ALG1,CNTN2,ACSL6,TCF4,NEU4,SYNE1,PSD3,OBSL1,TNS2,ARHGAP9,DICER1,ZMAT3,TIE1,TK2,CSMD1,PARD3,CABIN1,TNS1,PIK3R5,ZMYND8,TUBB2A,SGK3,UBC,UCHL1,PLPPR2,VGF,MICAL1,VLDLR,ZIC2,SLC26A10,ZNF142,ZNF189,DPYSL5,ANKS1B,PMEPA1,EMSY,PRDM2,ADAMTS9,SCG2,SNX27,CAB39L,PCBP4,MPPE1,KAT6A,SLC39A12" Drug ctd:C038091 butylparaben CTD 2.89E-18 1.42E-13 4.72E-15 5.37E-14 71 158 "ABAT,ACTN1,UNC5A,CASK,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CAMK2B,SYT6,CACNA2D2,DLGAP3,NRXN1,NRXN2,DCC,MAGI2,CHRDL1,DLG4,GRIN3A,SHANK1,DPP6,ERBB2,ERBB4,CACNG2,FGFR1,FYN,GABRA4,GABRB1,GLS,GPER1,STMN2,GRIA2,GRIA4,GRIK2,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,IL1RAPL1,NXPH3,NF1,NRCAM,NTRK2,NTRK3,CNTN3,PLIN1,MAPK3,RELN,MDGA2,ROBO1,STX1B,HES6,NLGN1,SLC1A2,SLC1A3,SLC1A6,SHANK2,SLIT1,SPP1,UNC5B,STXBP1,SYP,TSC2,VLDLR,SLC17A7" Drug ctd:D019422 Dietary Sucrose CTD 1.92E-17 9.40E-13 3.03E-14 3.45E-13 248 946 "TTYH1,ACLY,NCKAP5,ADCY2,SLITRK1,CCDC85A,ADD2,CDC7,ERMN,GRAMD1B,USP31,UNC5A,RNF150,PTCHD1,LRFN2,SNX32,BBOX1,ARMC12,PPFIA4,CPNE5,DNAH17,BRINP2,ATP6V1G2,BARD1,HCN2,CACNA1G,MMD2,CA4,CACNA1E,DIRAS1,KALRN,HAP1,CAMK2A,CAMK2B,CAMK2D,CH25H,P2RX6,DGKI,SLIT2,RAB33A,FADS2,SULT4A1,IGLON5,CNR1,COL11A2,NRG2,MFSD4A,FAM171B,CRHBP,HAPLN1,CRYBB1,AATK,TENM4,CSF1R,CSF3R,RIMS4,CST3,SLC45A1,FAM131B,NOS1AP,TOX,DBI,GSDME,ARNT2,GRIN3A,HS3ST2,CALN1,SHANK1,SLC25A18,EBF1,EFNA2,RGS17,SRPK3,HSD17B14,ENPP6,NCALD,APC2,RCSD1,CACNG2,TMEM132C,ACSL4,PPP1R1B,OLFM1,FGF11,SCARA3,PSD2,EFCAB2,SPECC1,TRIM16,PRELID3A,NSG2,DACH2,DLL3,B3GAT1,GABBR1,GABRA5,FAM184B,MTHFD2,GCK,GDF9,GPR162,CYP46A1,PCDH17,PPARGC1A,GLI2,RAB30,AIFM3,GNAO1,LILRB4,STON1,GPR26,STMN2,PLCD4,SERP2,GRIN1,GRM1,PTPRT,RNF165,HAS2,GPR45,HRH3,IGFBPL1,CELF5,ATCAY,BTBD17,IGF1,IGFBP1,LRRC25,NIM1K,PLD5,IGSF1,ITPKB,CDH20,KCNA6,KCNC2,KCNF1,KCNJ4,KCNJ9,KCNK2,KCNMA1,KCNQ2,KCNQ3,KPNA5,SYTL4,SCAMP5,MMP17,MPP2,JAKMIP3,MT3,HS6ST3,MYH3,MYH7,MYT1,RCOR2,NEFM,NELL1,NFE2L2,NINJ2,NPY,NPPA,NPTX2,NRCAM,HCN1,NTRK2,OLR1,OXTR,PCDH8,PDE1B,PIRT,PDGFRA,SLC10A4,PFKFB3,PFKFB4,PGAM2,GDAP1L1,PLIN1,PLP1,EPB41L4B,POU3F4,PPARA,MAPK4,LAMA1,GDPD2,TMEM104,PTPRZ1,MARCH1,FAT4,DBX2,RGS7,RAVER2,PNMA8A,ELMOD1,SELL,GALNT10,PPP1R9A,SHC4,CCDC92,ST8SIA1,ANKRD6,RPH3A,PEX26,SLC6A7,SLC6A11,KDM4D,SLC8A1,RADIL,BTBD7,LGI3,SORCS3,FAIM2,SCN3B,SOX10,LHFPL4,NFASC,FCHO1,MLC1,SYP,MCF2L,ADGRL3,PCDHGA1,PCDHB9,PCDHB4,HIF3A,SIRT1,CHST8,GPR161,HEY1,TIMP4,TLL2,PRRT1,TNR,TMPRSS5,FAM155A,OSBP2,BEST1,TSPAN11,RBFOX3,KCNK12,ZIC2,TRIM9,SLC26A10,LMAN2L,CAMK1G,VANGL2,SLC39A12,CBLN2,PRRT4,SPATA13" Drug 2268_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.67E-17 1.80E-12 5.62E-14 6.40E-13 74 175 "DPF1,ADD3,NME5,ALCAM,MARK4,BMP7,ST3GAL5,GYG2,USP2,CLGN,DNAJB5,PDE4DIP,KIAA0513,RIMS3,CTIF,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,RASGRP2,TUBB4A,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,GLS,STON1,GPR37,PCLO,KIF5C,MAP2,MITF,NAP1L3,PCBP3,TMOD2,SERPINE2,SERPINI1,PIK3CD,PKIA,PRPH,LRRC49,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,ZNF365,ARHGEF40,TNIK,ZCCHC24,KIF21B,PEG10,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,WSCD1,DMXL2,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C,AP3B2" Drug 994_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.83E-17 2.86E-12 8.66E-14 9.85E-13 78 191 "ASPHD1,NDRG2,APP,PPP4R4,ARRB1,CDK13,PDE8B,MARK4,MTMR3,RAB29,CACNA1D,CAMK2B,KYAT1,SCARB1,CLGN,FOXN3,AKAP12,ARHGEF10,PDE4DIP,RASSF2,DBN1,ARMCX2,G3BP2,SLC12A6,DTNA,OPTN,EFNB3,ENO2,VPS26C,ZNF589,FGF12,GPR153,CSPG5,FYB1,GALC,DISC1,GRB10,SPACA9,MAP4K5,KCNH2,KIF5C,LIG4,LMO2,LYRM9,CNOT4,NPR2,PALM,PDE4A,SLC25A23,PLTP,GRAMD1C,SAMD9,PTCH1,CEP97,FAM184A,CARF,RASA3,PEX26,SLC6A8,BTBD7,SLC22A4,LIMCH1,WDTC1,ZCCHC24,SPTAN1,TROVE2,TTBK2,PLCB1,ZNF34,KCTD2,TNNT1,TPM1,TRPC1,VGF,MAP3K12,GDPD5,MVB12B,RNF170" Drug 4821_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.82E-17 3.83E-12 1.13E-13 1.28E-12 74 177 "ADD3,NME5,CDC14B,ST3GAL5,SCAPER,CACNA1G,BAIAP3,CDK5R2,USP2,CDH18,CLGN,AKAP7,NECTIN3,CPS1,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TMCC2,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,PTK2B,TUBB4A,DPYSL4,FYN,CYP46A1,GLS,STON1,PCLO,RNFT2,KIF5C,VWA5A,MXI1,NAP1L3,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PLCD1,PRPH,SH3GL3,ASAP3,ST6GAL1,SYBU,WDR47,FAM214B,PKNOX2,ARHGEF40,CCDC88A,ZCCHC24,KIF21B,SOX15,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,RPGRIP1L,TGFBR3,HEY1,NPL,RUNDC3B,DNAJC12,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug CID000005070 riluzole Stitch 1.01E-16 4.93E-12 1.41E-13 1.60E-12 73 174 "ASIC1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,ASIC3,NRG2,GRIN3A,CACNG7,CACNG2,NRG3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GFAP,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNA4,KCNC1,KCND3,KCNK1,KCNK2,KCNK3,KCNN1,KCNN3,MAP2,NOS1,KCNK10,PKD1,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC1A2,SLC1A3,SCN3B,NFASC,ZFP91,VGF,STMN4,SLC17A7" Drug 3873_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-16 7.16E-12 1.99E-13 2.26E-12 73 175 "ABHD6,ADD3,NME5,ALCAM,SRPX,APLP1,ADGRB2,BMP7,ST3GAL5,GYG2,RAB29,SYNGR3,CLGN,LHX2,CLCN4,WHRN,AKAP12,PDE4DIP,RIMS3,ARMCX2,OPTN,EFNA3,EFNB3,ENO2,RASGRP2,TUBB4A,FYN,STON1,GPR37,SYNPO,KCNB1,KIF5C,VWA5A,MPP2,MXI1,PCBP3,TMOD2,SERPINI1,PIK3CD,RETREG1,LRP12,GRAMD1C,PRPH,LRRC49,PTPRH,FAM184A,TTLL7,SH3GL3,ASAP3,CPEB3,ST6GAL1,ARHGEF40,TNIK,ZCCHC24,NMNAT2,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,SYNE1,TGFBR3,HEY1,BEX4,RUNDC3B,UCHL1,DNAJC12,ZNF45,REEP1,SLC30A3,SLC17A7,ITM2C" Drug ctd:D008044 Linuron CTD 1.58E-16 7.72E-12 2.09E-13 2.37E-12 60 129 "ACTN1,LRRC7,DOC2A,DPP10,APAF1,BMPR1B,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CAMK2B,CAMK2G,CD81,MYOM2,CHGA,DLGAP3,NRXN1,NRXN2,DCC,MAGI2,DLG4,DPP6,CACNG7,EGFR,ERBB2,ERBB4,CACNG2,FYN,GABRA4,GABRB1,GLS,STMN2,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,IL1RAPL1,IGF1,NF1,NRCAM,NTRK2,RELN,MDGA2,ROBO1,RXRA,HES6,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,UNC5B,STXBP1,SYP,TSC1,TSC2,CADM1" Drug CID000001727 4-AP Stitch 2.82E-16 1.38E-11 3.64E-13 4.14E-12 94 258 "ACHE,ADORA1,ADORA2A,ADORA3,PHF12,KCNAB2,ATP1A2,ATP1A3,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALB2,KCNAB3,ASIC3,CHRM1,EDN1,EPB41,KCNMB2,HSPA12B,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAP43,KCNMB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1B1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MTR,MYBPC1,NOS1,NPR2,KCNK10,PRKCB,PRKCG,RAB3A,KCNIP3,KCNIP2,SCN4B,HSPA4L,SCN3B,SYN1,SYN2,SYP,TRH,UBTF,KCNAB1,ST8SIA2" Drug 3993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.05E-16 1.50E-11 3.84E-13 4.37E-12 73 177 "ABAT,ABHD6,ADRB2,MTUS1,SHROOM2,CDC14B,ARNTL,MARCH3,BRINP2,ST3GAL5,HIP1R,CBFA2T2,WHRN,ABCG1,FEZ1,PDE4DIP,CTH,RIPOR2,KIAA0513,DNAJC6,PLPPR4,SRGAP3,EFNA3,RGS17,RASGRP2,TAOK3,ATP8A1,TESK2,BAIAP2,DPYSL4,NBEA,SORBS1,PNMA2,FYN,CYP46A1,PCDH17,RND1,GLS,STON1,GUCY1B1,DIPK1A,ITGA7,KCNH2,KIF5C,MEF2C,TAGLN3,PCDH9,PDGFRA,ENPP2,SERPINI1,RETREG1,PRPH,PTCH1,RGS4,SH3GL3,ASAP3,WDR47,KDM4B,TNIK,ZCCHC24,ARHGAP26,CEP68,RGL1,SYT11,VAMP1,SYT1,COBL,TNS1,DNAJC12,TRIM9,SLC30A3,WNK1,PLSCR4" Drug 4349_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.38E-16 1.66E-11 4.15E-13 4.72E-12 74 181 "ADD3,NME5,ALCAM,MARK4,N4BP2L1,ST3GAL5,RAB29,USP2,CLGN,CLCN4,AKAP12,RIMS3,ARMCX2,DNAJC6,ST8SIA3,TSPAN5,OPTN,EFNB3,RASGRP2,STX2,TUBB4A,HPCAL4,DPYSL4,FYN,STON1,NXPH3,KIF5C,VWA5A,MX1,MXI1,MYCN,NAP1L3,PDE1C,PDE4A,TMOD2,PGAM2,SERPINE2,SERPINI1,PIK3CD,RETREG1,PLCD1,PRPH,LRRC49,PTCH1,FAM184A,TTLL7,SH3GL3,PPM1E,ASAP3,CPEB3,ZNF365,FAM214B,ARHGEF40,CCDC88A,TNIK,ZCCHC24,KIF21B,SSTR2,ELOVL4,RGL1,STXBP1,TRIM2,RALYL,HEY1,ICAM5,TNS1,RUNDC3B,SSBP2,UCHL1,DNAJC12,ZIC3,REEP1,SLC30A3,SLC17A7" Drug CID000001207 MK-801 Stitch 4.06E-16 1.99E-11 4.85E-13 5.52E-12 103 296 "ACHE,ADORA1,ADORA2A,ADORA3,RGS20,CA4,CACNA1D,CACNA2D1,CACNB2,CALB1,CALB2,NGB,CAMK2B,CAMK2D,CCK,CHRM1,CHRNA4,CHRNB2,CNR1,CREM,CTNND2,DBI,DLG4,GRIN3A,DRD1,DTNB,EEF1A2,EIF4G2,RGS17,OLIG2,ENO2,DMTN,ERBB4,PPP1R1B,FOXM1,FOLH1,B3GAT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,DISC1,GFAP,GLRB,GNAL,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,HBA1,HTR2A,MAP2,KITLG,NCAM1,NF1,NOS1,NPY,NTRK2,OPRL1,PDE2A,PDE4B,PDYN,PENK,ZDHHC8,PPP3CA,PPP3CC,PRKCG,MAPK3,PRODH,PTCH1,PTN,S100B,SLC1A2,SLC1A3,SOX10,NPAS3,DDN,SST,ARC,TAC1,TACR1,NTSR2" Drug ctd:D000447 Aldehydes CTD 4.40E-16 2.16E-11 5.14E-13 5.85E-12 197 720 "VWA5B2,ABAT,FAM43B,GALNT16,DSCAML1,ADRB2,OSBPL6,SRPX,MARCH4,GOLGA7B,PDZD4,CNIH2,CDK10,KIAA1614,SFMBT2,PPP4R4,ARRB1,DACT3,TMEM108,RNF182,TTC9B,ADGRB1,RGS9,BMP7,BAIAP3,CA4,DIRAS1,CCK,SLC5A11,INA,DCLK1,CRLF1,ARHGAP22,NRXN2,NGEF,CP,CRYM,CSF1R,CSF2RA,FEZ1,CHD5,RIMS4,PDE4DIP,ARHGEF4,RIMS3,AIF1L,KIAA0319,LYPD1,CCDC3,ARRDC4,EEF1A2,TMTC1,FAM13A,EBI3,MRO,PLXNC1,TMEM74,CEND1,F5,REEP2,EFEMP1,GTF2IRD2,HPCAL4,C1orf61,AGAP2,EFCAB2,SORBS1,NSG1,TMEM151A,FYN,GAD1,BRPF3,JPH4,GBX2,ALDH1L1,GFRA1,KCNMB4,GNAO1,C1QL4,CIT,LINC00839,LINGO1,GUCY1B1,SLC2A6,TOX2,PADI2,FRMD5,HMX1,ATCAY,ICA1,BTBD17,NKD1,NIM1K,IGSF1,ITGA7,KCNH2,KCNN1,KIF5C,KLRC3,L1CAM,LMO2,NAT8L,MAPT,SYT9,CHST6,ADAM11,LAYN,FXYD7,NAP1L3,RCOR2,NEFM,NEUROD2,NOVA2,NPTX1,SLC11A2,OLR1,ZDHHC22,PDE2A,DUSP26,SERPINE2,CAMKV,TMEM38A,KCTD15,JAKMIP1,PLIN1,CDIP1,NECAB2,ING3,SEPT4,FA2H,GRAMD1C,SMIM10L2B,PRPH,GDPD1,LAMA1,PTX3,PID1,TMEM255A,FAM184A,RAP1GAP,RASGRF2,RADX,SLC6A15,RET,KLHDC8A,EPHA10,RPS6KA2,MEG3,SOX8,SCN4B,TNFRSF19,ELMOD1,ABLIM3,SLC1A2,ZNF365,LIMS2,SLC6A8,SLC8A2,EFHD1,SLN,MAST1,OGDHL,SNCA,UNC5B,NFASC,SSTR2,ELOVL4,STAC2,SEPT3,ARC,SYN2,CAMTA1,WSCD1,TCF7,OBSL1,PCDHA3,PCDHA1,TF,ENHO,TIAM1,BEX4,TPM1,NPL,TRO,VAV1,VGF,LMF1,LAT2,CELF4,DPYSL5,SLC30A3,PMEPA1,PRDM8,HRASLS,TMEM63C,ADAMTS10,PRRT4" Drug 5017_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.83E-16 2.37E-11 5.51E-13 6.27E-12 74 182 "ABHD6,ADD3,LTBP4,APLP1,DNAH17,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,WHRN,RIMS3,ARMCX2,DNAJC6,TMCC2,FRY,OPTN,EFNA3,EFNB3,TBC1D16,TUBB4A,CORO2B,ATP8A1,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,AHDC1,GLS,STON1,KCNH2,KIF5C,MAP2,MITF,MPP2,MXI1,NEK1,NPY,NRGN,PDE4A,SERPINI1,PIK3CD,PRPH,PTCH1,RAB3A,RPS6KA2,SH3BGR,SH3GL3,ASAP3,WDR47,FAM214B,CCDC88A,TNIK,ZCCHC24,KIF21B,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,SMG6,TRIM2,TGFBR3,HEY1,RUNDC3B,TRPC3,DNAJC12,SLC30A3,GDPD5,SLC17A7,PLSCR4" Drug CID000003816 NSC759587 Stitch 6.07E-16 2.97E-11 6.76E-13 7.69E-12 137 444 "ABAT,ACHE,ADAR,ADORA1,ADORA2A,ADORA3,AMH,GAS7,APP,ATP2B2,BCL2L2,BCS1L,BSN,CA4,CACNA1D,CACNA2D1,CACNB2,CALB1,CALB2,CCK,SCARB1,CHRM1,CPNE6,CLU,CNR1,PICK1,DLG2,DLG4,DRD1,EEF1A2,OPTN,EIF4G2,ENO2,EPB41L1,GPHN,NCALD,NRN1,CACNG2,PTK2B,AGAP2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GFAP,GFRA1,GGT7,GGT5,GLRB,GLUL,GPR37,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GSTM5,IL1RAPL1,GSTT2,IGFBP1,ITPKA,KCNA1,KCND2,PACRG,MAP2,KITLG,MSR1,MT3,NOS1,NPY,NRGN,NUCB1,OLR1,OMG,PDYN,PENK,SERPINI1,GPSM2,PRKCB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK10,PTPRZ1,ENOX1,GSTCD,FBXW7,S100B,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SLC8A2,SNAP25,SOX10,SPTAN1,SST,SYN2,SYP,SYT1,SYT4,TAC1,TAC3,TACR1,MLST8,HEY1,TNFRSF1B,TRH,SGK3,PORCN,SLC30A3,PRDM2,SCG2,SLC17A7,SLC17A6,NETO2" Drug ctd:D004390 Chlorpyrifos CTD 7.25E-16 3.56E-11 7.90E-13 8.99E-12 247 968 "ASIC1,ACHE,SLITRK1,AXIN2,FZD9,ADRA1D,ADRB2,AP1B1,AGT,ALCAM,ALK,AMPD3,LRFN1,CDC42BPA,SEMA7A,APAF1,APOC1,SEMA4G,PPP4R4,TMEFF1,ARRB1,ATM,ALDH7A1,MTMR9,BCHE,FGF17,AP1M1,CAMK2A,CAMK2B,SYT6,CCK,USP2,CD86,SCARB1,CD81,DLGAP2,FOXN3,CHGA,CHGB,CHRM1,CHRM4,SYNPR,CHRNB2,SLIT2,CLCN3,SLC24A2,ABCG2,ABI3BP,RBM39,CRHBP,GDA,CLIP3,CHD5,CST3,DZIP3,TCAF1,MATR3,RIMS3,DNAL1,SPATA2,FAM107B,DLG2,DLG4,GRIN3A,DRD1,DTNB,DNM1L,ST8SIA3,EDNRB,RASGRP1,FRY,EGFR,EIF5,ELAVL4,EPHA5,TUBA1B,TUBB3,FKTN,TESK2,FGF1,FGF11,PRKAG2,NOP56,CINP,CGREF1,STAG2,DKK3,GAP43,GFAP,GFRA2,GGT7,RND1,TXNL4A,GLRB,PCLO,GRB10,GRIA1,GRIA2,GRIA4,GRID1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRM2,GRM5,GRM7,GSTM5,GSTT2,HMGB1,HNRNPK,HP,NEGR1,HSP90AA1,HTR2A,HTR5A,IGF1,IGFBP1,KIT,L1CAM,MAG,MAP2,SYT9,EFHB,MEF2C,MEIS2,MOBP,MOG,SCG3,MX1,MYCN,MYO5A,MYO7A,FXYD7,NCAM1,NEFM,NEFH,NEUROD1,NFE2L2,NFIX,CNOT4,NPY,NPTX2,NRCAM,NTRK2,NTRK3,IGSF11,OPRL1,OXTR,PAK3,PCSK2,PDE1C,PDE3B,PDYN,GPR85,PENK,TMOD2,PFKFB3,PFKFB4,ABCB1,PCDH18,ING3,SH3KBP1,POU3F2,MED1,MINDY2,LRRN3,PPP3CA,PRKAB2,RASGEF1B,PRKCB,MAPK3,MAPK8,HYDIN,RELN,PTK2,PYGM,KHDRBS2,RET,ROBO2,BAALC,FAM192A,S100B,DGLUCY,SCP2,SGK1,SLC1A2,SLC1A3,SLC1A6,FAM81A,SLC1A7,SLC6A8,SLC12A2,EFHD1,SLIT1,SNCA,USP33,SOX3,HECW1,MYCBP2,BEX1,SRPK2,SST,SSTR2,ERBIN,TTBK2,ADHFE1,SULF2,ARC,SYP,TAC1,CNTN2,TCF4,ZEB1,PCDHA6,ZNF106,AKTIP,CDH22,TJP1,TK2,TLR4,ZFP91,LRRC8A,BEX4,TNR,RBFOX2,ZNF346,TSN,UBC,AMOT,VLDLR,RBFOX3,LAT2,ZIC1,ZBTB16,SLC30A3,SLC38A1,CSDE1,CIAPIN1,SEMA3B,FZD3,RTN4,NLRP3,VANGL2,ZDHHC20,SENP7" Drug ctd:D010862 Pilocarpine CTD 7.58E-16 3.72E-11 8.08E-13 9.19E-12 100 286 "ASIC2,ASIC1,ACHE,SLC12A5,ADORA1,ADORA2A,ADRA1B,ALAD,SPARCL1,ANK3,APLP1,AQP4,PDXK,ATP2A2,BCHE,CACNA1A,CACNA1B,CACNA1D,CALB2,CDH2,CHRM1,CHRM4,SLIT2,CNN3,CNR1,AKAP5,SLC32A1,DMD,DPYSL2,DRD1,ABCC5,EFNA3,EGFR,EGR3,EPHA5,PTK2B,GABRA1,GABRA4,GABRA5,GABRG2,GAD1,GAD2,ZNF274,GAP43,GRIA1,GRIA2,GRIK1,GRIK2,GRIK5,GRIN1,GRM1,GRM2,GRM3,GRM5,GRM8,PTPN5,KCNMA1,KCNN1,KCNN2,KCNN3,LAMP2,MEF2C,NOS1,NPY,NOVA1,NOVA2,NPTX2,HCN1,NTRK2,NTRK3,OGG1,P2RX7,PCSK1,ABCB1,POLG,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,PTK2,PTPRZ1,QDPR,RET,S100B,SCN2B,SCN8A,SLC6A1,SLC6A11,SLC12A2,SSTR1,SSTR2,SYP,TAC1,SIRT1,TJP1,TNR,TRH,VGF,SLC17A7" Drug ctd:C069837 fullerene C60 CTD 1.20E-15 5.89E-11 1.25E-12 1.43E-11 350 1501 "VWA5B2,SERPINA3,ASIC1,ACHE,GPRIN1,XKR4,GALNT16,SLITRK1,ADD1,AXIN2,PLEKHH1,ADORA1,PWWP2A,ADRA1D,ADRA1B,SLC24A4,AP2A1,AP1B1,HECW2,PLA2G6,C1QTNF1,PCDH10,AMPD2,LRFN1,OGT,SEMA7A,FGD2,PPFIA2,APBA2,GAS7,CACHD1,PRX,ARNTL,ARSE,ASGR1,MARCH3,DNAH17,PTCH2,ALDH4A1,ATP1B3,ATP6V0A1,RGS11,GPR146,ARHGEF7,C1QC,AP1M1,CACNA1I,CACNA1G,BSN,IL33,MMD2,CACNA1D,CACNA1E,CALB2,KALRN,CANX,HIP1R,USP2,CBFA2T2,MYOM2,CDC25B,DCLK1,ARHGAP33,CRLF1,CHRM1,CHRM4,ZFYVE9,FAM189A2,DNAJB5,QKI,WHRN,IFFO1,AHCTF1,NRG2,CDC42BPB,C2CD2,SH2B1,CRY2,CRYBB1,NCOR1,GDA,CLIP3,CRYM,TENM4,CSF1R,SUSD5,PDE4DIP,SDC3,CALY,ARHGEF4,NRSN1,GPSM1,KIF26A,DGKB,DCTN1,C2CD2L,MED24,RHOBTB1,NTM,SGSM2,TMCC2,SLC29A4,NR1D2,CDON,SLC12A6,CASP8AP2,DTNB,TOM1,DUSP9,DNM1L,EDN3,PHC2,EEF1A2,TMTC1,EFNA3,EFNB3,KMT5B,RGS17,ELN,EML1,PAN3,DMTN,RASGRP2,APC2,TMEM74,PIPOX,TLR7,HSPA12B,ARMCX1,CLVS1,CHST15,BAIAP2,AGAP3,FOXO3,FLT1,AKAP3,FAM49B,TRIM16,GPR153,NSG1,B3GAT1,ABLIM2,AHCYL1,FAM120B,GHDC,TMEM8B,CPLX2,GBX2,SRCAP,GPR162,PCDH17,PPARGC1A,GJB1,MSL3,GNAL,PRRC2B,GP1BB,B4GALNT4,GPR22,STMN2,GRB10,GRIK1,GRIN1,GRIN2D,ATE1,CIT,GSTM5,ZBTB49,MFSD2A,MUM1,PTGDR2,MAN1B1,ATXN2L,ELOVL5,HMGCL,CFAP126,HSPA1L,CELF5,IDH3B,MYLK2,IGF1,IGFBP1,HES5,ITGA7,ITGAM,KCNN3,KIFC3,KLRC2,IPO5,TTYH2,MAP6,AQP11,MBP,BCO1,MYH3,MYO7A,NELL2,NEUROD2,NFIX,NINJ2,CNOT4,NPY,NPPA,NRGN,NTRK3,NUCB1,OGG1,OLR1,OPCML,PAK3,PAX6,CDK18,PDE4D,PDE1B,GNG2,CYTL1,CDK14,PGAM2,NLGN3,PIK3CD,XRN1,PLP1,PLTP,PURG,PDZRN4,RETREG2,MBOAT7,IRX1,PPP5C,PRKACB,PKIA,PRKAR1B,PROX1,MASP1,BCAS3,DEF8,STK32A,RIPOR1,RAB3A,RAB3IL1,SH3TC2,ATG16L1,RASGRF1,VEPH1,DUSP15,PRRT2,RFX3,RGS3,RGS12,TTLL7,SETD5,KIRREL1,RYR3,S100B,FOXRED2,SEMA6D,HOGA1,ASIC4,SEC14L1,SOX6,MRAS,TRA2B,COPZ1,RASA3,SH3BP2,ITSN1,SH3GL3,ST6GAL1,SYBU,ST3GAL3,SLC2A5,EPN2,SMTN,KANSL3,SLC6A8,YPEL4,SLC8A1,SLC14A1,SCMH1,SLC20A2,SLC22A4,SLN,SMARCA4,OGDHL,SNAP25,FAIM2,PDZD2,ZCCHC24,LHFPL4,SPP1,KDM4C,DBNDD2,ZBTB43,LMO3,TAB2,THSD1,SSTR2,MAPK8IP3,TTBK2,STAC2,ADHFE1,SEPT3,FAM168A,KLHL7,MLC1,PLCB1,SYN1,TACR1,MCF2L,TAL1,UNC5D,WSCD1,TCF4,SATB2,WASHC4,SYNE1,TMEM151B,PCDHB3,AKNA,ARHGEF12,HIF3A,CCDC173,ATP13A2,THBS4,MTMR14,TIE1,RELL2,BHLHB9,ZFP91,TNS1,CHST5,SMUG1,LRRC24,TRIO,NTSR2,UBTF,OSBP2,CCDC136,WNT7A,PORCN,ATP6V0E2,ZNF142,ZBTB38,ZBTB16,MEIS3,SLC17A6,MVB12B,CAMK1G,VANGL2,AAAS" Drug 5460_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.27E-15 6.21E-11 1.29E-12 1.47E-11 78 200 "ACTN2,AMT,APC,PPP4R4,RGS20,PLA2G4C,CADM3,BAIAP3,ADGRG1,CHRNB2,STOML1,SULT4A1,LY86,CRMP1,ARHGEF4,CTIF,TRAPPC9,ATN1,EGFR,ING4,ELN,C3orf18,ERCC2,IGSF6,RRAGB,OLFM1,HPCAL4,NSG1,SEPT9,NEU3,GDF9,GFER,C1QL1,GLS,GNAO1,GRK4,RAPGEF1,GRIA1,HRH3,VSIG4,KCNB1,KCNQ3,MAP4,MAPT,MEF2C,MGAT3,ADAM22,TAGLN3,MYCN,ZNF862,NEUROD1,NOVA2,PIK3CD,PLP1,PRKAR1B,MAPK10,RELN,RFX2,RGS12,ZFHX4,TCP11L1,FAM214B,SLC11A1,SNCA,ZCCHC24,ZNF423,ARHGAP26,SPTAN1,ATP10B,ACSBG1,JMJD6,ARC,DICER1,UCHL1,XRCC4,MKRN3,ZNF154,SSPN" Drug ctd:C035988 procymidone CTD 1.78E-15 8.72E-11 1.76E-12 2.01E-11 66 156 "ACTN1,LRRC7,DOC2A,DPP10,ATP2A2,NRP2,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CAMK2B,CAMK2G,CD81,CHGA,ASIC3,DLGAP3,NRXN1,NRXN2,CLU,NCAN,DBI,DCC,MAGI2,DLG4,DPP6,DRD1,CACNG7,EGFR,ERBB2,ERBB4,CACNG2,FYN,GABRA4,GABRB1,GLS,STMN2,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,IL1RAPL1,MBP,NF1,NFIX,NRCAM,NTRK2,PDCD2,RELN,MDGA2,ROBO1,RXRA,HES6,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,UNC5B,STXBP1,SYP,TSC2,CADM1,TUBA1A" Drug CID000005657 NSC7524 Stitch 1.80E-15 8.82E-11 1.76E-12 2.01E-11 73 182 "ASIC1,ACHE,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CBS,CCK,CACNA2D2,ASIC3,CHRM1,CHRNA4,CHRNB2,DBI,DMPK,CACNG7,CACNG2,PTK2B,B3GAT1,GAD2,NKX6-2,MSTN,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,CIT,NODAL,NPY,NPPA,PDE1C,PDE1B,ENPP2,PDYN,PENK,PKD1,RYR1,RYR3,SCN2A,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC6A1,SLC6A11,PALLD,SCN3B,SST,SYN1,SYN2,TACR1,TRH,ST8SIA2" Drug 6671_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.94E-15 9.50E-11 1.86E-12 2.12E-11 74 186 "RALGAPA1,ABAT,APAF1,ADGRB2,ST3GAL5,CDK5R2,CA12,HAP1,USP2,CHN2,DNAJB5,CREB5,ABCG1,VCAN,PDE4DIP,CNTNAP2,CTH,KIAA0513,DNAJC6,JAKMIP2,PLPPR4,SRGAP3,DSCAM,EDN1,EFNA3,RGS17,ETV1,CEND1,CACNG3,ATP8A1,SORBS1,PDLIM5,FYN,NEU3,PCDH17,RND1,GLS,FERMT2,GSN,GUCY1B1,DIPK1A,ITGA7,KCNN2,KIF5C,LIFR,VWA5A,MAP2,KITLG,ADAM22,TAGLN3,PDGFRA,PENK,SERPINI1,RETREG1,TNPO2,PRPH,PID1,ENOX1,RGS4,FBXW7,SH3GL3,TNIK,ARHGAP26,ELOVL4,RGL1,SYT1,COBL,R3HDM1,TNS1,LILRA4,RUNDC3B,SSBP2,DNAJC12,SLC17A7" Drug ctd:C009618 "O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate" CTD 3.56E-15 1.75E-10 3.36E-12 3.82E-11 80 211 "SYN3,ACHE,SEMA6A,ALK,DOC2A,ANK3,APLP1,APOC1,PPFIA3,ATP2B2,BCHE,NRP2,BID,CACNA1B,SLC25A14,INA,NOG,CPNE6,NRXN1,NRXN2,CNR1,CNTFR,RIMS4,PLXNA4,ERC2,NOS1AP,TOMM20,DCTN1,DLG4,DPYSL2,FIS1,SEMA3D,SH3GLB1,EFNB3,TENM1,ELAVL3,EPHB1,ACSL4,FGF11,FGF14,ATP5PD,FOXG1,SEMA4D,CSPG5,SDCBP2,GAP43,GRM2,CPT1C,IL12A,MYH6,NCAM1,NDUFA5,NEFM,NEFH,NF1,NKX2-2,OPHN1,ABCB1,NLGN3,SEMA5B,RELN,RET,ARX,NLGN1,ZNF423,SPTB,NFASC,VPS13A,SYN1,SYN2,SYT1,SEMA4A,CNTN2,TF,TNR,PPIL6,AMOT,WNT7A,DPYSL5,MFF" Drug 3087_UP Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.02E-15 1.97E-10 3.72E-12 4.23E-11 75 192 "SYN3,AMH,BIN1,CDC42BPA,AQP4,ARRB1,DNAH17,CACNA1G,INA,NEURL1,RAB33A,CLU,CREM,HAPLN1,CRYBB1,NCOR2,ABCG1,MICAL2,SIPA1L1,USP6NL,EDRF1,DOCK4,CTIF,DLG3,CDON,EDIL3,SGK2,EFNB3,C3orf18,EPHB1,FGFR1,BAIAP2,C1orf61,PDLIM5,ALDH1L1,GNG4,GPM6B,GRIA1,GRM7,PADI2,KCNJ3,KCNJ5,KIF5C,MAP4,MOBP,MYCN,NEFM,NEUROD1,KCNK10,PCDH9,PDE4B,GPR173,MTRF1L,PLXNB1,MARCH1,PID1,TMEM255A,TTLL7,PNMA8A,ROM1,FRMPD1,SLC8A1,ARHGEF40,SLC11A1,PALLD,IZUMO4,RAP1GAP2,SYN2,SZT2,PSD3,CHST8,TNS1,PCBP4,NUP214,SSPN" Drug 6454_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.12E-15 3.00E-10 5.45E-12 6.20E-11 71 178 "DPF1,ADD3,NME5,APLP1,ST3GAL5,SGCE,CACNA1I,RAB29,CDK5R2,CLGN,WHRN,COL9A3,AKAP12,PDE4DIP,DOCK4,KIAA0513,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,STX2,SPEG,TUBB4A,C1orf61,DPYSL4,SORBS1,FYN,CYP46A1,RAB40B,STON1,ITGA7,KIF5C,MPP2,MXI1,CDK14,SERPINE2,SERPINI1,PIK3CD,SLC25A23,PRPH,PTCH1,RPS6KA2,SH3GL3,PPM1E,WDR47,ARHGEF40,LIMCH1,TNIK,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,POPDC3,WSCD1,TRIM2,HEY1,BEX4,TNS1,RUNDC3B,DNAJC12,NDRG4,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 4388_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.12E-15 3.00E-10 5.45E-12 6.20E-11 71 178 "DPF1,KIAA1324,MARK4,BMP7,ST3GAL5,BAIAP3,CDK5R2,CDH18,CLGN,WHRN,AKAP12,CRYM,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TMCC2,TSPAN5,EFNA3,EFNB3,FAM13A,RASGRP2,STX2,TUBB4A,ATP8A1,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,KIF5C,VWA5A,MAP2,MPP2,NAP1L3,PDE4A,SERPINI1,PIK3CD,PRPH,PTAFR,GAL3ST4,RPS6KA2,SATB1,SH3GL3,ASAP3,WDR47,FAM214B,PKNOX2,SLC6A8,ARHGEF40,LIMCH1,ZCCHC24,KIF21B,NMNAT2,ARHGAP26,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TGFBR3,HEY1,RUNDC3B,DNAJC12,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug CID000002284 baclofen Stitch 1.02E-14 4.98E-10 8.90E-12 1.01E-10 74 191 "ABAT,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ATP1A3,SGCE,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CCK,CACNA2D2,CNR1,SLC32A1,DRD1,CACNG7,EIF4G2,GPHN,CACNG2,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRK4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IGF1,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,MAP4,NPY,NPPA,OPRL1,PKD1,RYR1,RYR3,SLC6A1,SLC6A11,SST,JMJD6,TACR1,MLST8,TRH,DPYSL5" Drug ctd:D003024 Clozapine CTD 1.20E-14 5.87E-10 1.03E-11 1.17E-10 122 392 "DPF1,SERPINA3,ADCY5,AXIN2,ADORA2A,AGT,OSBPL8,CDK5R1,CACNA1A,CAMK2A,CAMK2B,CAMK2D,CCK,CCKBR,DCLK1,NUMBL,CHGA,CHN1,CHRM1,CLTA,CLTB,ABCG2,CLOCK,CRHBP,ABCG1,NCAN,CST3,DRD1,DRP2,EGR3,ERBB2,ERBB4,PPP1R1B,HPCAL4,NPTN,CAMKK2,ABLIM2,GABBR1,GABRA1,CHL1,GABRB3,GAD1,GAD2,DISC1,CPLX2,GFAP,NTNG2,PCSK1N,GNAS,RAPGEF4,GRIA1,GRIA2,GRIK2,GRIK5,GRIN1,GRIN2C,NR3C1,HMGCR,HTR2A,IGF1,JAK2,KCNA1,KCNH2,KCNK2,LSS,MAOB,MBP,MOBP,NFE2L2,NPY,NPTX2,PDE4A,PDE4B,PDE1B,PENK,PFKP,ABCB1,SERPINE2,PKM,PLP1,PPM1B,PPP1R1A,PPP3CA,PPP5C,PRKACB,PRKCB,PRKCZ,MAPK3,MAPK9,RELN,WBP1L,RASGRF1,RGS4,RGS7,RORB,KCNIP3,STX1B,RXRG,SGK1,SLC1A2,SNAP25,TNIK,SPP1,SST,STX1A,STXBP1,SYT11,VAMP1,ARHGEF9,PLCB1,ARC,SYN2,SYT4,SYT5,TAC1,TRIM2,THRA,VSNL1,MAP3K12,SLC17A7,SLC17A6,RTN4" Drug ctd:D004397 Fonofos CTD 1.37E-14 6.73E-10 1.16E-11 1.32E-10 191 714 "ADCY2,ADCY8,FZD9,ADRB2,SLC44A5,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,APP,LGR5,CDK10,ASPH,ZNF583,CADM3,KIF1A,ADAM23,NRP2,CD38,CDH8,LARGE1,ZNF445,UBE2L6,RAB3C,JAM2,CLCN4,TMEM59L,NGEF,LY86,MYRIP,NRG2,CRMP1,ATRNL1,CNTNAP2,ERC2,CTNND2,SIRPA,DCC,ARMCX2,FBXO25,SV2B,SV2A,AK5,HS3ST2,CALN1,DRD1,RGS17,BSCL2,EPB41L1,EPS8,ZNF549,CDHR1,NRN1,ZNF585B,FABP7,FGF12,AFF2,HHIPL1,FYB1,PHYHIPL,MEGF10,GABRA2,GAD1,GALR1,ZNF559,SYT17,NTNG2,LNX1,GPM6A,MCHR1,GRIA4,GRIK3,GRIN2C,GRM2,GRM7,PTPRT,GSTM5,SOX21,GUCY1A2,MAEL,PADI2,GPR45,FRMD5,HLF,ZNF491,USP51,IRF8,LAMA2,LIG4,MATK,MATN3,MBP,MN1,JAKMIP3,MT3,MYCN,FXYD7,NCAM1,NEFM,NELL1,NEUROD2,NPTX2,NTRK3,NUCB1,PENK,CYTL1,GDAP1L1,PIK3CD,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RAP1GAP,RASGRF1,BEND5,KHDRBS2,RET,FIGN,RFX4,ZDHHC4,ZNF671,RIMKLA,HUNK,CCDC112,SALL1,ATXN1,SCP2,HES6,SEC14L1,GALNT10,SH3GL2,FERMT1,ST6GAL1,SLITRK3,DZIP1,ZNF365,SLC8A3,TMEM132D,ELMO2,SPHKAP,INAVA,SNRPN,SOX2,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,FNDC9,SYP,ASTN2,PCDHGB7,NAT16,TMEM121,HHIP,TIE1,TIMP4,PRRT1,LILRA4,IL34,TRH,RUNDC3B,TMEFF2,FLRT2,VLDLR,KCNK12,ZIC1,ZIC3,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PRDM2,PLD4,DNAH10,SSPN,NETO1" Drug 7324_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.58E-14 7.74E-10 1.31E-11 1.49E-10 70 177 "ABHD6,ADD3,NME5,MARK4,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,STX2,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KIF3A,PADI2,KIF5C,MITF,MPP2,MXI1,SERPINE2,SERPINI1,PIK3CD,PKIA,PRPH,PTCH1,RAB3A,SH3BGR,SH3GL3,PPM1E,SYBU,WDR47,FAM214B,PKNOX2,LIMCH1,ZCCHC24,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,GDPD5,NAV2,SLC17A7,ITM2C" Drug 6276_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.68E-14 8.22E-10 1.37E-11 1.56E-10 71 181 "ABHD6,ADD3,NME5,APAF1,MARK4,BMP7,ST3GAL5,SCAPER,CACNA1G,RAB29,CLGN,CACNA2D2,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,MBNL2,STX2,TUBB4A,BAIAP2,DPYSL4,GPR153,FYN,CYP46A1,RAB40B,STON1,RNFT2,PADI2,INPP5B,KIF5C,MPP2,MXI1,PCDH9,PDE4A,SERPINE2,SERPINI1,PIK3CD,RETREG1,PKIA,PRPH,MYH14,RPS6KA2,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,CCDC88A,ZCCHC24,THSD1,MAPK8IP3,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,KIAA0930,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,NDRG4,REEP1,SLC30A3,SLC17A7" Drug 2234_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.72E-14 1.33E-09 2.19E-11 2.49E-10 75 198 "DPF1,SYN3,ASIC1,TKTL1,AP2A2,NME5,ALCAM,MRTFA,AMPD3,BIN1,CDC42BPA,APOC1,ASCL1,CCDC181,N4BP2L1,SYNJ1,SCAPER,SEPT7,CHM,RAB33A,SULT4A1,BAG4,SNCAIP,CSF1,RIPOR2,HDAC4,TBC1D5,SRGAP3,EDN1,HIPK3,HEYL,FHL1,PRELID3A,OGA,RND1,GPER1,ADAMTS8,GRM3,SOX21,IL11RA,KCNMA1,SMAD1,MGAT3,MOBP,NPPA,PENK,PLCD1,PACSIN1,C19orf57,PPARA,PPP2R2B,CEP41,GRAMD1C,PROX1,RELN,RAD52,KCTD17,SALL1,ASIC4,ZNF821,SH3BP2,SLC1A7,PKNOX2,EMC1,ATP11A,TBCEL,TCF4,TEK,AP4E1,THRA,ICAM5,TNS1,SEZ6L,TPM2,MVB12B" Drug 2152_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.61E-14 1.77E-09 2.85E-11 3.25E-10 74 195 "C3orf14,ACTN2,ANK3,FGD2,DDO,APOC1,CDC14B,RASL11B,SLC4A4,PROM1,CA12,MAGI1,B4GALT6,ABCG2,FAM149A,ARHGEF10,NCAN,RIMS2,EDRF1,NOS1AP,ARHGAP24,SEMA3D,ELAVL4,C3orf18,ERBB2,ETV1,TUBB4A,DLC1,FGFR1,GPR153,ZNF44,GABRB1,GALC,ATP8A2,ALDH1L1,PCDH17,GNAL,STON1,STMN2,GRM7,ITIH2,KCNH2,MAP4,CD200,NPR2,NTRK2,PBX1,MTRF1L,SYTL2,ACSM5,SUSD4,ENOX1,ZFHX4,NEK11,SEMA6D,SCN3A,STUM,SLC1A3,SLC14A1,KIF13A,ZHX3,SSTR2,DIP2A,CAMSAP2,SYNE1,TEX15,TGFBR3,TK2,RUNDC3B,FAM155A,SLC30A3,FZD3,PAK5,SSPN" Drug 3614_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.70E-14 1.81E-09 2.88E-11 3.28E-10 75 199 "GRAMD1B,PLA2G6,C1QTNF1,SYT13,MRTFA,AMPD3,AMPH,BIN1,APAF1,MARK4,ATP1A2,ATP2B2,ST3GAL5,CFAP410,CACNA1A,CACNA1D,CACNA2D1,CALB2,USP2,CLCN4,HOMER3,TCEAL2,HDAC9,RASSF2,RIMS3,HEPH,SPOCK3,SV2A,SRGAP3,DNAH9,EFNB3,STX2,APC2,FGF12,FHL1,NSG1,HBS1L,ALDH1L1,LILRA2,GRM1,KLF12,HTR2A,INPP5B,LSS,ZNF862,NF1,NOVA2,SNTG1,PALM,PKN2,PTAFR,ELOVL2,RAB3IL1,CCDC40,RAD52,C1orf54,RASA3,SLC6A9,SLC11A1,SHANK2,NMNAT2,IZUMO4,SPTAN1,POGZ,PHLDB1,POPDC3,TAC3,ROBO3,HIF3A,TIMP4,SPHK2,ZNF154,PRDM10,NUP214,TIGD6" Drug ctd:D015655 1-Methyl-4-phenylpyridinium CTD 3.81E-14 1.87E-09 2.91E-11 3.32E-10 373 1659 "CPNE2,ABR,ASPHD1,ACADM,ACHE,AS3MT,ELFN2,SLITRK1,ADORA1,ADORA2A,SLC24A4,AP1B1,AGT,OSBPL1A,ALAD,ALCAM,KCNT1,GPRASP2,SYT13,AMH,AMPD2,CNTNAP1,APC,VAT1L,AQP4,SFMBT2,PDXK,ZBTB10,NCOA1,ATP1B3,ATP2B1,ATP2B2,ALDH7A1,B3GALT2,ADGRB2,ADGRB3,BCL2L2,HCN2,BCS1L,FGF17,PROM1,FUBP1,LDLRAD4,CA4,DIRAS1,CALM1,NGB,SLC25A14,SYT6,VSTM2A,CARS,RUNX1T1,CBS,KYAT1,AIFM1,CD86,ARHGEF2,SEPT7,CDC27,CDC42,CDH2,CDH10,DCLK1,CDH18,LARGE1,MAGI1,CDO1,CDR1,TBRG4,CLGN,COPB2,CHGA,CHN2,SYNPR,ZBED5,SLC22A6,NRXN3,TPP1,FAM19A5,MAP4K4,CNTFR,FAM149A,SLC25A27,COL9A2,COX4I1,CP,FAM171B,RBM39,CREB5,SLC32A1,CS,LRIG1,VCAN,PLXNA4,SLITRK5,CTH,CFAP61,CTNND1,CYBB,MATR3,RIMS3,PHYHIP,SPOCK2,AIF1L,SIRPA,DBN1,JAKMIP2,ZNF804A,TIAM2,MAGI2,LYPD1,SPOCK3,G3BP2,KIF19,CHRDL1,DLG4,RAB39B,HS3ST2,SLC29A4,ARRDC4,FARSB,ABCC5,DNM1L,EBF1,EDIL3,EEF1A2,SEMA3D,TMTC1,TMEM132E,ELAVL3,ELAVL4,HSD17B14,EN2,MTSS1L,SEZ6,EPS8,MRPL10,TBC1D16,ACSL4,TUBA1B,TUBB3,TUBB4A,RACK1,FCGRT,FDFT1,OLFM1,FGF11,FGF13,AMOTL2,ATP5PD,PCYOX1,SYNCRIP,FLNC,NOP56,SYT3,SORBS1,TPPP3,DKK3,GAA,ARPP21,GALR1,SALL3,MTHFD2,STARD10,GART,DNER,SRCAP,GFAP,NFU1,PCDH17,PPARGC1A,RND1,RAB30,PCDH11X,GPT2,GPR19,NUDT21,GPR37,GRB10,GRIA2,C1QL4,RFFL,GRIN2D,NR3C1,GRM7,GYG1,FAM222A,UBE2QL1,IGSF21,PADI2,NXPH2,ELOVL5,SYNPO,HMGCL,NEGR1,HSPA1L,SHISAL1,SOWAHA,IGF1,TMEM240,SLC6A17,ITGAM,KCND2,KCNJ4,KCNJ5,KCNJ11,KCNK3,KIF5C,TTYH2,LAMP2,LSAMP,GPR155,MAOB,MAPT,LRP1B,MMP16,MMP17,CPNE9,FXYD7,HNRNPM,NASP,NCAM2,NEFM,NELL2,NEUROD2,NFE2L2,ALDH1L2,NHLH1,NNAT,NOVA1,NPTX2,NRGN,DDR2,OGDH,OPRL1,KCNK10,PCDH9,CDK18,PDCD2,PENK,TMOD2,GDAP1L1,PKD1,PKM,PLCB2,PLXNB1,PSAT1,ING3,SH3KBP1,POU3F2,DRAM2,IRX1,PPP1R1A,PPP2R2B,LRRN3,MAPK3,EPDR1,MAPK7,MAPK8,MAPK9,MAPK10,PSD,SLC22A23,PLPPR1,UHRF1BP1,NCR3LG1,PTN,PTPRH,PTPRN,PTPRO,MARCH1,RAB5B,C1orf54,FAT4,RBBP6,SLC6A15,RET,FIGN,RNH1,KLHDC8A,FBXW7,RPL38,LRRK2,MEG3,SOX8,TUNAR,WLS,KCNIP1,RYR1,MAPK12,SARS,CSRNP3,SCN3A,FNIP1,SFPQ,TRA2B,SHMT2,R3HDM2,CCDC92,SLC6A9,SLC9A5,SLC12A4,EFHD1,TET1,NAXD,SMARCC2,SMARCE1,SNCB,SNCA,FAIM2,SNRPN,KDM3A,SPP1,UNC5B,SPTAN1,NFASC,LMO3,CLSTN2,COLGALT2,SST,NKAIN2,STAC2,SUPT5H,PRRC2C,ABCC8,SYNE2,ANKRD28,C12orf76,ROBO3,MLST8,UNC5D,KLHL4,WSCD1,KIAA0930,CUX2,TCF7L2,PCDHB4,AKNA,ATP13A2,SIRT1,CHST8,NACC2,ICAM5,ASXL3,TLR4,ANKRD24,TNFRSF1B,TNS1,RBFOX2,RASD2,TPM1,TRH,TMEFF2,PDIA2,FLRT2,FAM181B,VGF,RBFOX3,XPO1,SLC47A2,PCDH20,ZNF708,KCNT2,ELFN1,CRB2,SHD,TMEM178A,SCG2,HRASLS,FAM13C,RTN4,HNRNPA3,FXR1" Drug CID000000806 "D-myo-inositol-1,4,5-triphosphate" Stitch 4.73E-14 2.32E-09 3.57E-11 4.06E-10 159 569 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1B,AGT,ANK2,ANK3,ANXA7,DGKZ,DGKD,ARRB1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BTK,CACNA1I,CACNA1G,CA8,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,HAP1,CAMK2B,CAMK2D,CANX,CCK,CCKBR,KRIT1,CD38,DGKI,LRBA,CACNA2D2,CHGA,CHGB,CHRM1,MYL6B,HOMER3,CABP1,PLCXD3,DGKB,DGKG,IP6K1,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,CACNG7,EGFR,RASA4,EIF4G2,EN2,EPB41L1,ERBB4,MRVI1,CACNG3,CACNG2,ST3GAL6,PPP1R1B,FGF1,ACTL6B,IP6K2,FOXM1,ATP2C1,B3GAT1,FYN,AHCYL1,IP6K3,MTHFD2,INPP5K,GPR75,ADAP1,PLCD4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,ACOT7,HTR2A,MYLK2,INPP1,ITPKA,ITPKB,KCNMA1,MATK,MYL3,P2RY13,NEUROD1,NPPA,OCRL,OXTR,P2RY1,PDGFRA,PIK3C2A,PKD1,PLCB2,PLCD1,PLCL1,EPN1,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTAFR,PYGM,QDPR,RAB3A,RGS3,RGS4,GSTCD,RYR1,RYR3,MAPK12,RASA3,FNDC3A,SLA,SLC8A3,SPTB,PLCB1,TAC3,TACR1,TPCN2,ACTR6,CABIN1,TRH,TRO,TRPC1,TRPC3,VIPR2,PLPPR5,PLD4" Drug 4768_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.61E-14 2.75E-09 4.17E-11 4.74E-10 69 177 "DPF1,ADD3,ADRB2,NME5,APAF1,MARK4,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,NECTIN3,AKAP12,PDE4DIP,DZIP3,ARMCX2,DNAJC6,TMCC2,OPTN,EFNA3,EFNB3,FAM13A,ENO2,RASGRP2,TUBB4A,FHL1,HPCAL4,DPYSL4,FYN,CYP46A1,RND1,GLS,STON1,KIF5C,MEF2C,MPP2,NAP1L3,TMOD2,SERPINE2,SERPINI1,PIK3CD,PLCD1,GRAMD1C,PRPH,RADX,NUDT11,SH3GL3,ASAP3,FAM214B,TNIK,ZCCHC24,KIF21B,PEG10,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,TNS1,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug ctd:C012568 terbufos CTD 5.77E-14 2.83E-09 4.22E-11 4.80E-10 191 724 "ADCY2,ADCY8,FZD9,ADRB2,SLC44A5,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,APP,LGR5,CDK10,ASPH,ZNF583,CADM3,KIF1A,ADAM23,NRP2,CD38,CDH8,LARGE1,ZNF445,UBE2L6,RAB3C,JAM2,CLCN4,TMEM59L,NGEF,LY86,MYRIP,NRG2,CRMP1,ATRNL1,CNTNAP2,ERC2,CTNND2,SIRPA,DCC,ARMCX2,FBXO25,SV2B,SV2A,AK5,HS3ST2,CALN1,DRD1,RGS17,BSCL2,EPB41L1,EPS8,ZNF549,CDHR1,NRN1,ZNF585B,FABP7,FGF12,AFF2,HHIPL1,FYB1,PHYHIPL,MEGF10,GABRA2,GAD1,GALR1,ZNF559,SYT17,NTNG2,LNX1,GPM6A,MCHR1,GRIA4,GRIK3,GRIN2C,GRM2,GRM7,PTPRT,GSTM5,SOX21,GUCY1A2,MAEL,PADI2,GPR45,FRMD5,HLF,ZNF491,USP51,IRF8,LAMA2,LIG4,MATK,MATN3,MBP,MN1,JAKMIP3,MT3,MYCN,FXYD7,NCAM1,NEFM,NELL1,NEUROD2,NPTX2,NTRK3,NUCB1,PENK,CYTL1,GDAP1L1,PIK3CD,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RAP1GAP,RASGRF1,BEND5,KHDRBS2,RET,FIGN,RFX4,ZDHHC4,ZNF671,RIMKLA,HUNK,CCDC112,SALL1,ATXN1,SCP2,HES6,SEC14L1,GALNT10,SH3GL2,FERMT1,ST6GAL1,SLITRK3,DZIP1,ZNF365,SLC8A3,TMEM132D,ELMO2,SPHKAP,INAVA,SNRPN,SOX2,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,FNDC9,SYP,ASTN2,PCDHGB7,NAT16,TMEM121,HHIP,TIE1,TIMP4,PRRT1,LILRA4,IL34,TRH,RUNDC3B,TMEFF2,FLRT2,VLDLR,KCNK12,ZIC1,ZIC3,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PRDM2,PLD4,DNAH10,SSPN,NETO1" Drug 2881_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.89E-14 2.88E-09 4.24E-11 4.83E-10 70 181 "ABHD6,NME5,SEMA6A,ALCAM,SRPX,APAF1,ARNTL,MARK4,ST3GAL5,RAB29,CLGN,UBE2L6,DNAJB5,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,MAGI2,OPTN,EFNA3,EFNB3,MBNL2,RASGRP2,STX2,TUBB4A,DPYSL4,SORBS1,FYN,RUNDC3A,STON1,TPPP,KCNH2,KIF5C,VWA5A,MAP2,MITF,MXI1,TMOD2,CDK14,SERPINE2,SERPINI1,PIK3CD,PRPH,LRRC49,PTCH1,TTLL7,SH3GL3,ASAP3,ZNF365,ARHGEF40,LIMCH1,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,WSCD1,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug ctd:D005419 Flavonoids CTD 6.01E-14 2.95E-09 4.27E-11 4.86E-10 274 1142 "ACADM,ASIC1,ACLY,ADARB2,ADCY2,ADCY6,ADCYAP1R1,ADD3,ADORA2A,ADRA1D,AGT,SYT13,AMPD3,PPFIA4,APAF1,GAS7,BCAS1,AQP6,ARNTL,ARRB2,ASPA,ATP1A3,SLC4A4,ATP2B3,AZGP1,BARD1,BBS2,BCHE,SYNJ1,SYNJ2,CACNA1E,DDR1,CACNA2D1,CACNG1,KALRN,CAPN3,SYT6,HIP1R,RGN,P2RX6,SCARB1,CD38,ENTPD2,CD81,SEPT7,CDH10,DCLK1,COPB2,CHGB,CHN1,CHN2,SYNPR,RAB28,SLC24A2,TPP1,NGEF,TJP2,ABCG2,RAB26,SLC4A7,CDC42BPB,HAPLN1,SLC32A1,CRYBB1,GDA,FEZ1,SIPA1L1,GALNT9,CST3,CYBB,MATR3,RIMS3,DGKB,BRINP1,DBN1,DBT,SPATA2,DCTN1,CEP170,SV2A,ARNT2,DNM1,OLIG1,NR1D2,CDON,ABI1,DRP2,ATN1,PDCD6IP,GNE,E2F5,ST8SIA3,OPTN,CELSR3,EIF5,TNK2,SEZ6,STX2,SPEG,CDKL3,RRAGB,CACNG3,CACNG2,PTK2B,POLR1B,BAIAP2,FOXG1,EVL,FLT1,PDLIM5,NPTN,CGREF1,ST6GALNAC3,DLL3,SARAF,DKK3,GABRG1,NEU3,MSTN,ARFIP1,PPARGC1A,GK,CRCP,GLS,GNAO1,GNAS,GPD2,ADAP1,GRIA1,PLCD4,GSTT2,GUCY1A2,WIF1,NXPH3,PACSIN2,HNMT,NEGR1,IDH3A,IDH3B,IGF1,HES5,ITGA7,ITGAM,KCNB1,KCNH2,KCNJ4,KCNJ11,KCNJ16,KCNN2,KCNN3,KLRC2,KLC1,LMO1,MAG,MAOB,MAT2A,MOBP,CD200,CCDC80,BCO1,SCG3,DDX25,MYH6,MYH7,MYO5A,FXYD6,NCAM1,NEFM,NELL1,NFIA,NINJ2,NNAT,NRCAM,NRGN,NTRK2,NUCB2,SETD4,ODF2,GPR88,OPA1,OPCML,CLDN11,OXTR,KCNK10,PC,PCSK5,PDE1A,PHKG1,NLGN3,PKD1,PLCD1,NECAB2,SPATA6,POLR2F,POU3F2,PPP1R1A,PPP2R2C,PPP3CA,PPP3CB,PRKCB,MAPK10,PRPH,KLK6,PTAFR,PTCH1,PTK2,PTPRO,PEX2,QDPR,CRTAC1,RGS3,RGS4,RPL15,KCNIP2,RTN1,ZNF354C,STX1B,SCN3A,SCN7A,SMPD3,SELL,SH3GL2,ST6GAL1,NLGN1,SEC31A,SLC6A9,SLC12A2,SLC20A2,RIMS1,SNAP25,SNCB,SNCA,LMBRD1,SNRPN,PDZD2,SOX11,CAND2,SPP1,DDN,SAMSN1,SSTR2,MPRIP,STX1A,SEPT3,NECAB1,ABCC8,SYN2,SYT5,MLST8,TCF4,TCF7,TF,ZMAT3,TGFBR3,THBS4,THRA,TJP1,TLR4,ZNF384,TRPC1,TST,UBC,UCHL1,UGT8,VIPR2,VSNL1,P2RY12,CLIP2,KCNK12,DPYSL5,CSDE1,SCG2,RTN4,NUP214" Drug CID000000681 dopamine Stitch 6.42E-14 3.15E-09 4.49E-11 5.11E-10 189 715 "ABAT,DGCR6,ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,OSBPL6,OSBPL8,AMT,PDXK,ATP1A3,ALDH7A1,RGS9,BSN,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CALB1,CALB2,CALM1,NGB,CBS,CCK,CCKBR,CBFA2T2,NOG,CHRM1,CHRNA4,CHRNB2,HOMER3,CNR1,COX4I1,CREM,CSNK1E,CALY,HDAC4,GSDME,SLC29A4,DRD1,EEF1A2,EN2,ENO2,ZMYND10,PPP1R1B,OLFM1,FGF14,ACTL6B,FOXM1,FYN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,ARPP21,INPP5K,SULT1C4,GFAP,GFRA1,GNAL,LOXL3,GNAS,PRLHR,GPR37,GRK4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,LINGO1,GUCY1A2,GUCY1B1,HBA1,HRH3,TNFAIP8L3,HLF,HTR2A,HTR5A,IGF1,IL12A,KCNA6,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,PACRG,MAOB,BEX5,NDUFA5,NOS1,NPY,NPPA,NPR2,OGG1,OPRL1,PAH,PDE3B,PDYN,PENK,FXYD1,PPP2R2C,PTPA,PPP2R5E,PRKCB,PRKCG,PKN2,PRKCZ,NDUFS7,PTX3,PPP2R3C,QDPR,RAB3A,SLC6A15,RET,RGS4,RGS10,LRRK2,CLIP1,ZNF354C,RYR1,RYR3,SAFB,MAPK12,SLC1A2,SLC1A3,SLC6A1,SLC6A11,RIMS1,SNAP25,SNCB,SNCA,SOX10,NPAS3,SST,SSTR1,SSTR2,ADHFE1,STX1A,SUPT5H,SYN1,SYN2,SYP,SYT1,TAC1,TACR1,MLST8,CUX2,ACTR6,NR2C2,TRH,NTSR2,HIRA,UCHL1,CLIP2,PORCN,SCG2,SLC17A7,SLC17A6,NELFE" Drug 5572_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.39E-14 3.62E-09 5.10E-11 5.80E-10 68 174 "DPF1,ADD3,NME5,KIAA1324,ST3GAL5,GYG2,USP2,CDH18,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,FAM13A,STX2,TUBB4A,HPCAL4,IQCG,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KIF5C,VWA5A,MXI1,NAP1L3,NEK1,TMOD2,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,SH3GL3,PPM1E,ASAP3,WDR47,CCDC88A,SLC9A5,TNIK,ZCCHC24,KIF21B,PEG10,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 4436_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.03E-13 5.02E-09 6.97E-11 7.94E-10 68 175 "ABAT,ABHD6,APAF1,CDC14B,ARNTL,BRINP2,ST3GAL5,HAP1,USP2,CHN2,ABCG1,LRIG1,PDE4DIP,ERC2,CTH,KIAA0513,RIMS3,DNAJC6,JAKMIP2,PLPPR4,EDN1,FRY,AASS,RGS17,PTK2B,TAOK3,BAIAP2,DPYSL4,FYB1,FYN,GAB1,GLS,STON1,TPPP,ITGA7,KCNH2,KIF5C,LIFR,VWA5A,MAP2,MAPT,ODF2,PCDH9,PDGFRA,SERPINI1,SYTL2,PTAFR,PTCH1,ENOX1,RGS4,RPS6KA2,SH3GL3,SLC15A2,KDM4B,FNBP1,BEX1,THSD1,ELOVL4,CEP68,RGL1,SYT11,SYT1,KIAA0930,CDK20,CHST5,SSBP2,CADM1,DNAJC12" Drug ctd:D007608 Kainic Acid CTD 1.20E-13 5.89E-09 7.96E-11 9.06E-10 73 195 "DGCR6,ADRA1B,APAF1,MPDZ,NRP2,CALB1,KALRN,CCK,AIFM1,CDC42,CHGB,ABCG2,QKI,CNR1,PICK1,CNRIP1,GRIN3A,EN2,FGFR1,SEMA4D,GABRB1,GABRB3,GAD1,GAD2,GAP43,GCNT2,GFAP,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,HPCA,IL12A,ITGAM,JAK2,KCNC2,KCNQ2,LMO1,MAP2,MT3,MYO9A,NCAM1,NFE2L2,NOS1,NPY,SLC11A2,HCN1,NTRK2,PAK3,PDYN,PENK,ABCB1,FXYD1,MAPK3,SNRK,SFPQ,SLC1A2,SLC8A3,ATF7IP,SPTAN1,SST,ARC,TAC1,SIRT1,TRH,UCHL1" Drug 3546_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.22E-13 5.97E-09 7.96E-11 9.06E-10 74 199 "ADCY2,BRAP,SEMA6A,MRTFA,ATP1A3,SCAPER,GYG2,CACNA1I,CA4,KALRN,CAST,RCBTB2,FOXN3,SLIT2,PLCH2,CNTNAP2,CTIF,MAGI2,DUSP9,EDNRB,HIPK3,C3orf18,RASGRP2,FOXG1,GPR153,GAB1,GABRA2,CHL1,ERAP1,TMEM8B,DISC1,GNAO1,GNG3,GPM6A,GPM6B,ATF7,TDRKH,LILRA2,GPR37,KCND3,KCNJ5,KIFC3,LAMA2,SMAD1,MARK1,BCO1,MSR1,NF1,NPY,NOVA2,NTRK3,OLR1,PLCD1,TMEM255A,RYR1,ZNF821,SH3BP2,RPH3A,PKNOX2,SORCS3,KDM4B,WDTC1,TSNAXIP1,ZSWIM8,SPTAN1,AJAP1,WSCD1,TCF7L2,PCDHA2,CHST5,AMACR,PDIA2,SLC30A3,ADAMTS9" Drug 2689_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.22E-13 5.97E-09 7.96E-11 9.06E-10 74 199 "ABAT,C3orf14,MTUS1,ADGRF5,SYT13,ANK3,SEMA4G,CASK,ATP1A3,CADM3,KSR1,FUBP1,CALB2,BRSK2,MAP7,NEURL1,CDH10,GPR37L1,NDST3,NMT2,DNAJB5,CABP1,COL9A3,CREM,NCOR2,ARHGEF10,SUSD5,SIPA1L1,PDE4DIP,GREB1,USP6NL,DRP2,RCAN1,ST8SIA3,HIPK3,SRPK3,F5,FER,C1orf61,SIGLEC8,GRIK2,ADAMTS8,GRIN2C,RASSF8,KCNN1,AFF1,MOBP,ADAM22,NEFM,SNTG1,PHKG1,PPP1R1A,RASGRF1,SUGCT,HKDC1,RPH3A,SLC11A1,SNAP25,ARC,SYT5,KIAA1107,PHF24,CRB1,TIAM1,TRPC3,TRPS1,UBE3A,FLRT1,VSNL1,KCNK12,EVI5,STMN4,HRASLS,JPH3" Drug CID000000923 sodium Stitch 1.27E-13 6.21E-09 8.17E-11 9.30E-10 234 944 "ASIC2,ASIC1,METAP1D,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,SLC12A5,SLC24A4,AGT,ANK2,ANK3,PHF12,KCNAB2,SLC7A14,PDXK,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ALDH7A1,BCHE,HCN2,BLM,NAE1,CA4,CA12,CACNA1D,CACNA2D1,CACNB2,CALM1,KYAT1,CCK,KRIT1,SLC5A11,INA,P2RX6,ENTPD2,LRBA,ASIC3,CHN1,CHRNA4,CHRNB2,SLC22A6,CLCN3,SLC24A2,SLC4A7,SLC4A8,CP,SLC32A1,CRYM,CNTNAP2,PYGO1,DCT,DCTN1,BLOC1S6,SACS,DLG3,DMPK,SLC29A4,SLC12A6,DTNB,EDN1,EDN3,SGK2,KCNMB2,SLC43A2,ERBB2,PIPOX,F3,PTK2B,SCML2,SLC9B2,ACTL6B,ATP6V1H,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,NKX6-2,ATP8A2,GART,DNER,GATM,GCK,DHRS4,GLS,POLL,PCSK1N,KCNMB4,LNX1,MCHR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,NR3C1,CIT,KAT7,GYG1,HMGCR,IGF1,IL12A,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCND2,KCND3,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,LIG4,MTR,FXYD7,NBL1,NPPA,HCN1,OGDH,P2RX7,ENPP2,PKD1,PKM,PLCB2,FXYD1,EPN1,HMGCLL1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,SLC26A11,GDPD1,PTPRB,PTPRG,RDX,SLC6A15,RPL15,UEVLD,GLDN,RYR1,RYR3,ATXN1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,ASRGL1,SGK1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC2A5,SLC6A1,SLC6A7,SLC6A9,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC11A1,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLCO1A2,SLC22A4,RIMS1,SCN3B,HECW1,SPP1,PEG10,SST,TAC1,ATP11A,TACR1,TJP1,ACTR6,NPL,TPM3,NR2C2,TRPC1,TRPC3,TRPM2,SGK3,UBE2H,SLC13A3,KCNT2,WNK1,SLC38A1,SLC17A7,KCNAB1,WNK3,SLC17A6,ST8SIA2" Drug CID000002910 cyclothiazide Stitch 1.49E-13 7.31E-09 9.38E-11 1.07E-09 48 103 "RIPK1,CA4,CACNA1A,CACNA2D1,CACNG1,SLC22A6,SLC24A2,NCAN,CACNG3,CACNG2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GFAP,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNMA1,MBP,PTPRZ1,SLC1A2,SLC1A3,SLC1A6,SLC8A2,TAC3,UBC,SLC17A7" Drug CID005183170 AC1NPPZW Stitch 1.49E-13 7.31E-09 9.38E-11 1.07E-09 48 103 "ASIC2,ASIC1,AMH,ANK2,ANK3,SLC2A11,CACNA1D,INA,ASIC3,COL4A5,NTM,ABI1,ABI2,SPEG,ACSL4,FGF14,FOLH1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCND2,KCND3,KCNJ3,KCNJ10,KCNK2,KCNK3,MX1,NEUROD1,HCN1,ENPP2,SERPINE2,GLDN,KCNIP2,SCN2A,SCN4B,ASIC4,BCAN,SCN3B,ZEB1,NPL,TRPC1,UGT8,PCDH15,NAV3,NAV2" Drug CID000003446 gabapentin Stitch 1.78E-13 8.72E-09 1.10E-10 1.26E-09 66 169 "ABAT,ASIC1,ADORA1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,SLC5A11,CACNA2D2,ASIC3,GRIN3A,CACNG7,CACNG3,CACNG2,FOXG1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GPT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,ATXN2L,KCNH2,MEIS1,MEST,PDYN,PENK,ABCB1,PKD1,PSAT1,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC6A1,SLC6A11,SCN3B,TPCN2,ETNPPL" Drug 6650_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.19E-13 1.07E-08 1.34E-10 1.52E-09 73 197 "DPF1,RALGAPA1,ADRA1D,SYT13,BEGAIN,ANK2,APAF1,APBB1,CDC14B,PPP4R4,ASCL1,ZSCAN18,ADGRB2,MPDZ,BMPR1B,CACNG1,KALRN,CBFA2T2,CDH10,DNAJB5,ABCG1,RIMS2,EDRF1,TOX,DAPK3,DBT,RUSC2,DSCAM,ING4,IGSF6,DLC1,OLFM1,FLT1,GAB1,NEU3,GNAO1,SPACA9,GRM7,ITIH2,KCNJ5,KCNQ3,SMAD9,AFF1,DDX25,NEFM,NRCAM,PENK,RETREG1,C19orf57,MAPK10,PTAFR,ZSCAN2,CCDC40,KCTD17,FBXW7,SLA,SLC11A1,SLC15A2,SNCA,KIF21B,HECW1,ARHGAP26,MCF2L2,SPART,ATP10B,SYN2,COBL,TACR1,LAT2,ZNF74,SPHK2,EVI5,STMN4" Drug ctd:D007657 Ketone Bodies CTD 2.23E-13 1.09E-08 1.35E-10 1.53E-09 147 522 "ACADM,ARID1A,PLEKHG5,ADCY2,GRAMD1B,AP2A2,ANK3,PKP4,APLP1,DGKZ,GPAM,APP,SPTBN4,ZBTB10,NCOA1,ATP1A1,ATP1A2,ATP2A2,ATP6V0A1,TTC9B,BMP7,CDK5R1,CACNA1D,CAMK2A,CAMK2B,SYT6,CARS,ARHGEF25,CERS5,MTMR7,SYNGR3,PLAA,CLCN3,CLTC,FBXO7,CNN3,MAGED1,MYRIP,AKAP12,CRMP1,CRY2,CALY,NOS1AP,TOMM20,DNM1,DNM1L,FIS1,EDNRA,ANKRD46,KCTD3,EIF5,MRNIP,CEND1,AMZ2,FDFT1,FGF14,ATP5PD,EVL,FAM49B,GABRA4,ZMYND11,ARPP21,ACSS1,CPLX2,GFRA1,RNPS1,ZNF638,FERMT2,GRIA2,GRIK4,PTPN5,KAT7,GYG1,PADI2,ELOVL5,ACOT7,CELF5,IGFBP1,KCNJ9,KCNN2,STXBP5,MAP4,MBP,PTOV1,SCG3,NASP,NPTX1,NRGN,OPRL1,P2RX7,PCSK2,OLA1,PFKP,SERPINI1,PLCD1,CDIP1,LRP12,SCHIP1,SEPT4,POLR2F,PPP1R1A,PPP2R2B,PPP3CA,PKIA,PSD,PTPRN2,RGS7,ZNF354C,STX1B,RXRG,SARS,SCP2,SCG5,BCAN,KBTBD4,CDK5RAP2,RIMS1,TNIK,MYCBP2,CLASP2,FCHO1,SYT11,JMJD6,SUPT5H,SYT5,TAC3,TCF4,PUM2,RIMBP2,R3HDM1,CABIN1,TP53BP1,TRPC1,CADM1,RPL7L1,UCHL1,MTCH1,MEAF6,VSNL1,CLDND1,ATP6V0E2,PLPP4,TMEM178A,SLC17A6,RTN4,HNRNPA3,RNF146" Drug CID000001248 AC1L1B1W Stitch 2.43E-13 1.19E-08 1.45E-10 1.65E-09 42 84 "ABAT,SLC12A5,ADORA1,CACNA1D,SULT4A1,DCTN1,BLOC1S6,DTNA,LRRC23,GPHN,CSPG5,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,MAP4K5,KCNC2,RIT2,SALL1,SLC6A1,SLC6A11,SLC12A2,ARC,ZEB1" Drug ctd:C523799 MRK 003 CTD 2.82E-13 1.38E-08 1.65E-10 1.88E-09 199 775 "ACTN1,AXIN2,GRAMD1B,ADORA3,SLC44A5,BBOX1,CDC42BPA,EPB41L5,GPAM,APP,CPNE5,SHROOM2,TMEFF1,RGS20,ASCL1,B3GALT2,ADAM15,BCL7A,ST3GAL5,WASF1,IL33,CACNB2,CAST,CH25H,CD86,CDH2,CDH10,CHN1,ARHGAP22,NGEF,FAM189A2,CNN3,CNR1,AKAP7,FAM149A,CDC42BPB,CREB5,ABCG1,RGS6,LRIG1,SOCS5,PLXNA4,PITPNM3,CTH,ARHGEF4,SCRN1,ARMCX4,ARMCX2,CEP170,SACS,RABGAP1L,FAM107B,KBTBD11,DMD,DSCAM,HEYL,EBI3,ELAVL4,EMX2,EPB41,EPHA5,EPS8,ERBB2,SIRPB1,FAM198B,TBC1D16,EFEMP1,FCGR1A,FCGRT,OLFM1,FGF13,MEX3B,FLNC,FOLR2,SORBS1,SPECC1,TRIM16,RASL10A,DLL3,MEGF11,MEGF10,GAP43,CPLX1,GATM,PPARGC1A,RUNDC3A,NTNG2,KCNMB4,FERMT2,GPT2,LILRB4,GPD2,PRUNE2,GPM6B,SPACA9,SERP2,GSN,RNF165,TMEM25,FRMD5,FRMD3,BACH2,VSIG4,ZDHHC15,CPT1C,IFI16,ZIC5,RBPJ,HES5,IL6R,KCND2,KCNK2,KCNMA1,KCNQ2,KIF5C,KIFC3,INSYN2,LMO2,KITLG,STK32C,MSR1,MSRA,NRBP2,MYCN,MYO6,IDNK,NEFM,TREM2,PBX1,PC,PDGFRA,SMOX,PCDH18,PLXNB1,PMP22,LRP12,PRRX1,EPB41L4B,PILRA,PPP2R2B,PKIA,SYTL2,PTN,ZIK1,RAB3IL1,ACSS3,BEND5,RGS4,RGS7,LGI2,ROBO1,FBXW7,ZNF671,S100B,FHOD3,SLC2A5,SLC12A2,ELMO2,SLC20A2,TET1,CXXC4,SORCS3,SNAP25,SNCA,PDZRN3,SOX11,SPP1,MIR100HG,PHLDB1,MCF2L,ACSL6,TRIM2,PCDHGB2,PCDHB7,CHST8,CRB1,TGFBR3,CDH22,HEY1,TIMP4,HEY2,NPL,RGMB,TST,UCHL1,CLIP2,ZNF23,EMX2OS,NDRG4,TCEAL7,CELF4,LAMP5,NAV3,RGS7BP,DOCK8,NLRP3,NHSL1,SSPN,SPATA13" Drug ctd:D013849 Thimerosal CTD 2.83E-13 1.39E-08 1.65E-10 1.88E-09 282 1198 "CLK4,FMNL2,OLMALINC,OSBPL8,TAOK1,C1QTNF3,LRRC7,SEMA6A,C1QTNF4,CEP126,FAM135A,PITPNM2,ANK2,EP400,LCORL,PPFIA4,APC,EPB41L5,LGR5,ARHGAP5,MARK4,DACT3,ATM,CADM3,KIF1A,DOCK11,ADGRB2,SNAI3-AS1,DST,RAB29,PTBP2,SYT6,SPAG9,CCNT1,AIFM1,CD86,SYNGR3,CD81,CDC27,CDH8,TBRG4,NOG,CHN2,PLEKHB1,CLU,TPP1,FBXO7,FADS2,HECTD1,NIPBL,IGLON5,FAM149A,ANKRD35,COL9A2,COX4I1,TCEAL2,BAG4,IGDCC3,CPS1,PREPL,C2CD2,ANKRD44,CS,SNCAIP,ARHGEF10,CNTNAP2,ARHGEF4,DCAF4,DOCK4,FGFR1OP2,GAPVD1,HDAC4,GIT2,SIRPA,DBN1,DCC,SPATA2,HEPH,ELMO1,RUSC2,MAGI2,KLHL3,CPEB2,SEZ6L2,EDNRB,EEF1A2,PHF20L1,MBNL2,PLXNC1,EIF4G1,SORBS3,ENO2,EPB41L1,STX2,SRRM1,ERCC2,CDHR1,MRPL10,ADGRV1,MRVI1,FABP7,TBC1D16,ACSL4,KAT8,FER,FGF11,SYNCRIP,SPECC1,USP16,STAG2,GABRA1,HBS1L,SEPT9,CRCP,RAB30,GLS,HTATSF1,GNAL,GNG4,TDRKH,GPR22,PCLO,PARD3B,GRIK2,GRIK5,GRIN1,MAP4K5,RASSF8,TOX2,KLF12,MIER3,HMGB1,AGBL5,USP51,NEGR1,AGFG1,HSF2,HSPA1L,IFI16,IGF1,C5orf24,GAREM2,RBPJ,ST7-AS1,TMEM240,KHK,TTYH2,LIMS1,SYTL4,HECTD2,FGFBP3,LSS,MAP4,MID1,MKLN1,MMP16,WDR49,PTOV1,MT3,MTR,MYO5A,MYO6,MYO9A,FXYD6,NASP,NCAM1,NDUFA5,SFR1,RCOR2,NEFH,NF1,NME4,NRDC,NTRK3,PC,PCSK2,TMOD2,PFKFB2,PFKFB4,PFKP,CDK14,PIK3C2A,ZNF655,SMOX,SLC25A23,MAGEL2,ING3,MBOAT7,PACSIN1,PRKAB2,MAPK3,MAPK8,MAPK9,BCAS3,GON4L,UHRF1BP1,PTK2,OCIAD1,EML5,MARCH1,PRIMA1,CCDC82,MRAP2,PRR5L,RIMKLA,PLPPR3,SOX8,RYR3,TRAPPC13,ATXN1,SFPQ,HSPA4L,CPEB3,CHD9,PREX2,RUFY2,SLC8A1,RAB3GAP1,SLC12A2,ATF7IP,SLC22A4,TET1,EPC1,SMARCC2,RIMS1,SNAP25,KDM4B,SON,TRERF1,KIF21B,BDP1,SP4,HECW1,ERC1,RBM26,NPAS3,CLASP2,ITPRID2,LARP4,NKAIN2,PRRC2C,SYNE2,ARC,TAF9,ADGRL3,TBL1X,ANO4,EHBP1,OBSL1,ARHGEF12,HIF3A,DICER1-AS1,CBX5,PRRT1,TP53BP1,TPD52,TPM4,NR2C2,CA14,TUBB2A,TMEFF2,LINC00645,UGT8,USP1,LMF1,RBFOX3,TRIM9,MKRN3,WNK1,CA10,CADM2,PRDM2,SLC38A1,EVI5,NAV3,PDSS2,HRASLS,KAT6A,PHTF2,JMJD1C,SENP7,JPH3" Drug 5763_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-13 1.44E-08 1.67E-10 1.90E-09 73 198 "ADCYAP1R1,AMPD3,SEMA7A,APAF1,APBB1,BCAS1,PRX,BRINP2,CFAP410,CALB2,CAMK2B,DLGAP2,NRXN2,RAB26,WHRN,NRG2,MICAL2,PHF14,ARHGEF4,MFAP3L,C2CD2L,DTNA,ABCC9,CELSR3,ING4,DENND4A,TUBB4A,CAMSAP1,FOXG1,C1orf61,PDLIM5,POLL,ATXN2L,ELOVL5,TJAP1,ITIH2,KCNN1,KHK,LAMA2,LMO2,VWA5A,MEF2C,TAGLN3,NDUFA5,P2RX7,PGAM2,PIK3R1,CEP41,MAPK10,PTN,ZSCAN32,PTPRN2,MARCH1,ENOX1,RFX2,SYNDIG1,STUM,SUPT20H,PPP4R3A,SORCS3,SCN3B,TAL1,PCDHGA10,SLC44A1,DAAM2,TPM1,RPRM,UCHL1,FLRT2,NDRG4,SPHK2,SEMA3B,SLC17A7" Drug 4101_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-13 1.44E-08 1.67E-10 1.90E-09 73 198 "ABAT,ADCY2,AGT,APOC1,APP,AQP4,PRX,ARHGDIG,BRINP2,SLC4A4,RGS11,SCAPER,BAIAP3,CA4,CACNA2D1,RUNX1T1,CCK,SLC16A4,CHI3L2,CLCN4,AKAP6,CABP1,CSF1,RGS6,LRIG1,MICAL2,SUSD5,NOS1AP,RIPOR2,FRMPD4,C2CD2L,TRAPPC9,DRP2,DSCAM,DYRK1A,EPB41,ERBB4,F5,SIGLEC8,GFER,GPR75,POLL,PRUNE2,SOX21,ADAM11,MSR1,MT1M,MYO7A,NPY,NTRK3,DDR2,PDE2A,SPATA6,POU3F2,PTH1R,PTPRN2,RGR,PBRM1,TMEM206,FOXRED2,ST8SIA1,MYT1L,SOX2,ARHGAP26,ATP10B,SST,MAPK8IP3,SYT5,CRTC1,AMACR,LAT2,PRDM2,KCNAB1" Drug CID000004873 K-Cl Stitch 3.31E-13 1.62E-08 1.86E-10 2.12E-09 156 567 "KCNH8,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,SLC12A5,ADORA1,ADRA1D,ADRA1B,ADRB2,AGT,AMPD2,AMPD3,MYH7B,AQP6,MARK4,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,KSR1,CA8,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALB1,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,ENTPD2,CHGB,CHRM1,MYL6B,SULT4A1,CREM,CRYM,CS,CSNK1E,CSNK1G3,EARS2,ZEB2,GSDME,DMPK,SLC12A6,DTNB,AASDH,EDN1,EDN3,EDNRA,EDNRB,PTK2B,ACTL6B,POLK,FOXM1,ATP2C1,GART,GCK,MSTN,SESN1,KCNMB4,GRIK1,GRIK4,NR3C1,GRM2,GSN,GUCY1A2,GUCY1B1,HMGCR,HSF2,HTR2A,IDH3A,MYLK2,KCNJ3,KCNJ4,KCNJ5,KCNK2,KCNK3,KCNMA1,MARK3,AQP11,SYT9,AFDN,MTR,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NBL1,NODAL,NOS1,NPY,NPPA,NPR2,KSR2,P2RY1,KCNK10,PDYN,PENK,PKM,POLG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,REV3L,RIT2,RNASE1,MYH14,RYR1,RYR3,SAFB,MAPK12,ARX,MYO18A,SMTN,SLC12A2,SLC12A4,SNAP25,PEG10,SST,SYN2,TAC1,TACR1,SMG6,ZEB1,TIMP4,ACTR6,TPM1,NPL,TPM2,TPM3,TPM4,TRH,WIPF1,SPHK2,SCG2,WIPF2,PLD4,FZD3" Drug 4237_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.40E-13 1.67E-08 1.90E-10 2.16E-09 66 171 "ABAT,ADRB2,NME5,EPB41L5,ARNTL,MARCH3,MARK4,BRINP2,NOL4,ST3GAL5,CACNG1,HAP1,HIP1R,CHRNB2,ABCG1,PDE4DIP,CNTNAP2,CTH,PLPPR4,EFNA3,RGS17,TBC1D16,PTK2B,TESK2,BAIAP2,DPYSL4,NBEA,FYN,CYP46A1,PCDH17,RND1,GLS,STON1,GUCY1B1,BACH2,DIPK1A,ITGA7,KIF5C,VWA5A,MAP2,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINE2,SERPINI1,PIK3CD,PRPH,ENOX1,RGS4,SH3GL3,WDR47,SLC15A2,TNIK,THSD1,ELOVL4,RGL1,SYT11,SYT1,COBL,TMOD1,RUNDC3B,SSBP2,DNAJC12,TRIM9,PLSCR4" Drug ctd:C487081 belinostat CTD 3.89E-13 1.91E-08 2.07E-10 2.35E-09 179 679 "CPNE2,RNF150,CEP126,PCDH10,AMPD3,USP28,EPB41L5,APOC1,SFMBT2,PPP4R4,ARRB1,ASGR1,ASTN1,NOL4,BMPR1B,SYNJ2,JAZF1,RAB29,CA4,CALB1,RUNX1T1,CCKBR,DGKI,CDC25B,CDH18,LGI1,NOG,ADGRG1,RCBTB2,CHGA,RAB3C,SLIT2,LHX2,RAB33A,KIAA1549L,NRXN2,CLU,NGEF,C4orf33,CNTN1,HAPLN1,NCAN,KIAA0040,ARHGEF4,ARHGAP24,DCC,C8orf34,MAGI2,RABGAP1L,ARNT2,DUSP9,EDN1,EDNRA,EDNRB,PLXNC1,LPAR6,EIF4G2,LRRC17,SEZ6,NCALD,CEP85L,PIPOX,EZH1,TAOK3,CHST15,SLC9B2,FLT1,EFCAB2,PNMA2,FUT9,GABRB3,GAD1,GAP43,DNER,GFRA1,FREM1,MAP7D2,MCHR1,STMN2,GRIK1,FAM19A2,PTPN5,FAM222A,WIF1,TOX2,NXPH2,NEGR1,IDH3A,IFI16,SHISAL1,IGF1,PLD5,HES5,INPP1,LRRTM1,OLFM3,KCNJ3,LIFR,DPP10-AS1,LMO2,MAP6,IL17D,SHC3,SESN3,SCG3,NEXMIF,BEX5,NDP,IDNK,NELL2,NPY,NTRK3,NUCB2,CNTN3,PCDH8,NLGN3,GDAP1L1,SERPINI1,SNX10,IRX1,ZFHX4-AS1,LRRN3,EPDR1,RELN,ELOVL2,STK32A,PTX3,VEPH1,PRIMA1,ROBO2,GLDN,HUNK,SOX8,RTN1,MIR124-2HG,SEMA6D,ELMOD1,IL17RB,SOX6,DOCK10,HKDC1,CNKSR2,SLC1A3,LRRC55,SLIT1,LIMCH1,SNAP25,TNIK,DOK5,KDM4C,PEG10,LMO3,COLGALT2,SMOC1,SST,EPB41L3,COBL,TACC1,ADGRL3,ZEB1,AKNA,CRB1,SPX,ZMAT3,GALNT17,HEY2,SGK3,FRRS1L,UGT8,RBFOX3,ZIC3,ZBTB38,ANKS1B,TUBA1A,SEMA3B,NAV3,SSPN,NETO2,CPNE4" Drug 4008_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.93E-13 1.93E-08 2.07E-10 2.35E-09 73 199 "ADD2,PLA2G6,PPP4R4,CADM3,ADAM23,ADGRB2,CFLAR,BMP7,SCAPER,BTRC,NEURL1,CDC42,MAGI1,NRXN3,NRG2,RGS6,DTNA,ABCC9,USH1C,HIPK3,SEMA3D,EFNB3,ING4,RGS17,EPHA5,FGF14,CAMSAP1,HPCAL4,AGAP2,PRELID3A,ATP8A2,GPM6B,CACFD1,GSTM5,ELOVL5,ICA1,IRF8,IL6ST,IL12A,KCNC1,MAPT,MARK1,MMP16,LYRM9,CNOT4,NOVA2,PCBP3,NLE1,POU6F1,PTCH1,PTN,PTPRN2,BEND5,RGS4,GSTCD,TMEM206,RPS20,KCNIP2,ZNF821,SNCB,SNCA,ZSWIM8,SPTAN1,CDK19,PHLDB1,COBL,ZEB1,TEX15,FLRT2,VGF,LAT2,WNK1,PARP6" Drug 4826_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.93E-13 1.93E-08 2.07E-10 2.35E-09 73 199 "MRTFA,TRMT9B,BIN1,EPB41L5,GAS7,SPTBN4,RGS20,CDK13,MARK4,ATM,GYG2,CACNB2,HAP1,KRIT1,CD86,CLGN,SOCS6,QKI,NRG2,RIMS2,DCAF4,DAPK1,SPOCK2,GSDME,EDN1,CDKL3,PIPOX,ANKMY1,RRAGB,F5,TUBB4A,AGAP2,AFF2,HBS1L,ERAP1,MALT1,LYVE1,RND1,GPER1,NR3C1,ICA1,JAK2,KCNB1,MGAT3,TAGLN3,NCAM2,NOS1,CNOT4,NPTX1,LRP12,PPP5C,PROX1,RELN,C1orf54,SLC25A36,SLN,KIF13A,PDZD2,ZC3H13,RBM26,THSD1,NXT2,MAPK8IP3,ARC,WSCD1,TCF7L2,RPGRIP1L,TEX15,CABIN1,TNS1,TRPC1,TUBB1,WNK1" Drug 3809_UP Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.93E-13 1.93E-08 2.07E-10 2.35E-09 73 199 "ADD2,SPARCL1,LTBP4,TRMT9B,APAF1,GAS7,ADGRB2,RGN,ABCG2,NRG2,PLCH2,ERC2,RIMS3,BRINP1,DCT,SMG7,TRAPPC9,DTNB,VPS13B,EZH1,REEP2,ABCA8,CAMSAP1,SEMA4D,FLT1,NSG1,ATP8A2,MYOZ2,ALDH1L1,POLL,LILRA2,ADAMTS6,PADI2,HSD17B1,KCNB1,MAG,MATK,MGAT3,MOBP,MYT1,NOVA2,NTRK2,P2RY1,PDE4A,GPR85,PLP1,POU6F1,PRKAR1B,PTCH1,ZMAT4,RGS12,SH3BP2,CNKSR2,SLC1A2,SLC2A5,SLC14A1,SLCO1A2,SLN,SOX2,IQSEC2,INKA2,ACSBG1,VPS13A,PCDHGA1,TK2,TMOD1,CHST5,HIRA,CADM1,AMOT,OSBP2,SLC30A4,SLC17A7" Drug 6524_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.93E-13 1.93E-08 2.07E-10 2.35E-09 73 199 "ACTN2,NME5,AK2,BEGAIN,AMPD3,CNTNAP1,GAS7,PLA2G4C,ADAM23,FGF17,NRP2,CA4,CACNB2,CAMK2G,USP2,ARHGEF1,CLGN,PLEKHB1,COL9A3,IFFO1,MAML1,SLC12A6,RCAN1,DTNA,HIPK3,EFNA3,EFNB3,ERCC2,NRN1,TUBB4A,CORO2B,OLFM1,FHL1,TBR1,GALC,GAP43,ERAP1,ALDH1L1,TDRKH,GSTM5,SOX21,RASSF8,HRH3,KLF12,HLF,HNMT,HTR2A,KCNH2,KPNA5,MAP4,MAPT,MSI1,MYH7,NDUFA5,NLE1,LRRN3,RNASE1,SBF1,CNKSR2,URGCP,SLN,SNCA,COLGALT2,TAL1,PSD3,HIF3A,SLC44A1,CABIN1,ZMYND8,AMOT,WIPF1,WNT7A,XRCC4" Drug 3510_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.98E-13 2.44E-08 2.54E-10 2.89E-09 68 180 "DPF1,ABHD6,ADD3,NME5,KIAA1324,ALCAM,APLP1,SEMA4G,MARK4,ST3GAL5,CBFA2T2,CLGN,PDE4DIP,NOS1AP,KIAA0513,CTIF,ARMCX2,TMCC2,EFNA3,EFNB3,MBNL2,RASGRP2,KIAA1109,DPYSL4,FYN,ERAP1,CYP46A1,STON1,TJAP1,KIF5C,MITF,MPP2,BCO1,ZNF862,NAP1L3,SERPINI1,PIK3CD,LRP12,PKIA,PRPH,PTPRH,RAB3A,FAM184A,NUDT11,SH3GL3,PPM1E,ASAP3,SYBU,FAM214B,ARHGEF40,CCDC88A,LIMCH1,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,OBSL1,HEY1,BEX4,TRIO,RUNDC3B,SSBP2,DNAJC12,REEP1,ITM2C" Drug 7236_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.98E-13 2.44E-08 2.54E-10 2.89E-09 68 180 "ADD3,NME5,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CLGN,AKAP12,CRY2,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,OPTN,EFNA3,EFNB3,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,TDRKH,STON1,KIF5C,MAP2,MITF,MPP2,MXI1,NEK1,SERPINI1,PIK3CD,PMP22,PKIA,GRAMD1C,PRPH,PTCH1,TTLL7,SH3BGR,SH3GL3,ASAP3,SYBU,WDR47,FAM214B,CCDC88A,SMARCD3,ZCCHC24,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,TMOD1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 5484_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.98E-13 2.44E-08 2.54E-10 2.89E-09 68 180 "ADD3,NME5,APAF1,CDC14B,SEMA4G,MARK4,ST3GAL5,BAIAP3,CDH18,CLGN,DOCK4,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,FAM13A,MBNL2,RASGRP2,STX2,CDKL3,PTK2B,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,COPS8,GLS,RAB40B,STON1,KIF5C,MXI1,NAP1L3,PDE4A,SERPINI1,PIK3CD,PRPH,PTCH1,RAB3A,PID1,TTLL7,NUDT11,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,ZCCHC24,KIF21B,SOX15,ZBTB43,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,KIAA0930,TRIM2,RPGRIP1L,GPR161,HEY1,RUNDC3B,DNAJC12,EVI5,SLC17A7" Drug 3643_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.08E-13 2.49E-08 2.57E-10 2.92E-09 69 184 "AGT,NME5,MRTFA,MARK4,RGS9,ST3GAL5,GYG2,BAIAP3,CDK5R2,CLGN,CLCN4,PDE4DIP,RIMS3,SPOCK2,ARMCX2,DNAJC6,FRY,EFNA3,EFNB3,FAM13A,MBNL2,AASS,RASGRP2,TUBB4A,DPYSL4,SORBS1,FYN,CPLX2,CYP46A1,GFER,RND1,GLI2,GLS,STON1,KCNB1,KIF5A,KIF5C,MEF2C,MN1,NAP1L3,PAH,TMOD2,SERPINI1,PIK3CD,PLTP,PRPH,PTAFR,RAB3A,ENOX1,SATB1,SH3GL3,ASAP3,SMTN,PKNOX2,KIF21B,SST,MAPK8IP3,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,SYNE1,GPR161,HEY1,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 5625_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.42E-13 3.15E-08 3.21E-10 3.65E-09 66 173 "DPF1,ADD3,ADRB2,NME5,APLP1,MARK4,ST3GAL5,BAIAP3,CDK5R2,USP2,CDH18,CLGN,WHRN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,FAM13A,SPEG,TUBB4A,HPCAL4,DPYSL4,FYN,CYP46A1,RND1,GLS,STON1,KIF5C,MEF2C,MPP2,MXI1,NAP1L3,SERPINE2,SERPINI1,PIK3CD,SEPT4,PRPH,PTCH1,RPS6KA2,SH3GL3,PPM1E,ASAP3,CPEB3,WDR47,FAM214B,PKNOX2,CCDC88A,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 3189_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.00E-13 3.43E-08 3.31E-10 3.77E-09 72 197 "ACTN2,ALK,AMT,ANK2,GAS7,DDO,ARHGDIG,ASCL1,ASTN1,ATP2B3,CA12,HAP1,RUNX1T1,CLDN10,SLC24A2,FAM131B,RIPOR2,JAKMIP2,DTNA,DUSP9,ING4,TNK2,CALCRL,ETV1,FABP7,ACSL4,AGAP2,PDLIM5,KHDRBS3,ADAM28,PCDH17,GLS,TOX3,GNAL,GNAO1,TDRKH,GRIK2,GRIN2C,GRM8,ICA1,KCNMA1,KPNA5,VWA5A,MARK1,LRP1B,MOBP,BCO1,MYCN,MYH7,MYO7A,NHLH1,NOVA2,TRHDE,PACSIN1,RALGDS,C1orf54,FAT4,RGS12,SCN8A,TRIM46,SH3BP2,SLC6A9,SHANK2,SLCO1A2,KDM4B,SAMSN1,MAPK8IP3,PLCB1,SYNE1,FAM189A1,SLC19A3,ARHGEF12" Drug 5641_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.00E-13 3.43E-08 3.31E-10 3.77E-09 72 197 "ASIC1,ADRA1D,MRTFA,APAF1,CDC14B,ADAM23,KSR1,HAP1,CLCN4,CLTB,WHRN,SNPH,CTIF,DSCAM,EFNB3,TNK2,TUBB4A,FGF1,FGF13,FGFR1,FGFR3,FHL1,FOLR2,CAMKK2,SIGLEC8,GFER,C1QL1,LYVE1,RUNDC3A,PRUNE2,GPM6B,GRIK1,GRIK2,GRIK5,GRM7,ATXN2L,ITGA7,KCNB1,KCNH2,MAN2A2,MAOB,MOBP,ADAM22,ZNF862,NCAM1,NPY,OMG,PCSK2,GPR85,PFKFB2,FXYD1,DCHS2,RELN,ZSCAN2,ZDHHC14,MYH14,FRMPD1,SHANK2,KIF13A,FAIM2,SOX2,EMC1,SPP1,BEX1,SYN2,ZEB1,RPGRIP1L,TRPM2,SPHK2,SLC30A3,KCNAB1,PAK5" Drug 4438_UP 2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.00E-13 3.43E-08 3.31E-10 3.77E-09 72 197 "ACTN2,ADCY6,AMH,PPFIA4,KCNAB2,ARRB1,PTCH2,N4BP2L1,KSR1,ST3GAL5,FUBP1,CDK5R2,CD86,SYNGR3,CACNA2D2,CHN2,TPP1,DNAJB5,AKAP5,CRYM,FEZ1,EDRF1,DGKG,BRINP1,DCT,MAGI2,SPOCK3,DTNA,ELAVL3,MRNIP,ETV1,FGF1,FOLR2,PDLIM5,FYN,GAB1,CHL1,MSL3,GNAO1,GPR17,STON1,CACFD1,IRF8,ITGA7,KCNH2,KIF5C,KIFC3,MYCN,OLR1,OPCML,CDK18,PDE4A,RETREG1,EPN1,SPATA6,PROX1,VPS13C,C1orf54,RNASEL,PRR5L,ZFP2,SUPT20H,BCAN,LIMS2,RBM34,ATP10B,ELOVL4,SYT1,TCF4,PCDHA6,SLC44A1,CDK20" Drug 6614_UP Apramycin [37321-09-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.00E-13 3.43E-08 3.31E-10 3.77E-09 72 197 "ADCY6,ADD2,ADORA1,ANK1,EPB41L5,AQP4,BRINP2,CCDC181,ATP2B2,ATP2B3,ADGRB3,BMPR1B,ENTPD2,NEURL1,DGKI,ARHGAP33,CRLF1,IFFO1,CHD5,CTNND2,ECE2,SPOCK3,DNAH9,NCALD,NRN1,DLC1,AGAP2,EFCAB2,OGA,SRCAP,PRUNE2,GRIA1,GRM1,ATXN2L,ICA1,C2orf72,IGFBP1,KCNB1,KCND2,VWA5A,MAP2,AFDN,MMP16,SLCO1C1,NRCAM,PALM,PLCB2,EPN1,SPATA6,PPP2R2B,PROX1,PTCH1,ZSCAN32,RAB3IL1,KCNIP2,KCNIP1,SLA,PEX26,SLC11A1,ZNF334,SOX10,DOK5,IZUMO4,ARC,TACR1,TCF4,CHST8,TRO,CA14,OSBP2,SLC13A3,KCNAB1" Drug 5704_UP Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.00E-13 3.43E-08 3.31E-10 3.77E-09 72 197 "ASIC1,ACTN2,SYT13,BEGAIN,BIN1,CDC14B,ARHGDIG,ASCL1,SYNJ1,CACNA1G,CALB2,CAMK2B,ZFYVE9,CLCN4,SNCAIP,RGS6,PDE4DIP,MAGI2,SV2A,DMPK,HS3ST2,DSCAM,DTNA,EFNB3,MRNIP,ETV1,FGF13,AFF2,GPR153,GABRA1,GABRA2,RUNDC3A,TDRKH,PCLO,RAPGEF4,GRIK1,IGFBP1,TJAP1,IL11RA,KCNH2,KCNJ16,MDFI,MGAT3,AFDN,ADAM22,PDE1C,PHKG1,PIK3CD,NLE1,PLCD1,SPATA6,RAB3A,RASGRF1,RGS12,CPEB3,KANSL3,MAPKBP1,SOX15,ARHGAP26,TROVE2,MAPK8IP3,SYN2,SYT5,TAL1,PSD3,PCDHA2,PARD3,VLDLR,LAT2,ADAMTS9,SEMA3B,SLC17A7" Drug ctd:D010278 Parathion CTD 7.03E-13 3.44E-08 3.31E-10 3.77E-09 207 822 "ACHE,ADCY2,ADCY8,ADD3,FZD9,ADRB2,SLC44A5,SEMA6A,ALCAM,ALK,AMPH,CDC42BPA,DDO,APP,LGR5,CDK10,ASPH,ZNF583,CADM3,KIF1A,ADAM23,BCHE,NRP2,CCK,CD38,CDH8,LARGE1,ZNF445,UBE2L6,RAB3C,JAM2,CLCN4,TMEM59L,NGEF,LY86,MYRIP,NRG2,CRMP1,ATRNL1,CNTNAP2,ERC2,CTNND2,SIRPA,DCC,ARMCX2,FBXO25,SV2B,SV2A,AK5,HS3ST2,CALN1,DRD1,EGFR,RGS17,BSCL2,EPB41L1,EPS8,ZNF549,CDHR1,NRN1,ZNF585B,FABP7,FGF12,AFF2,HHIPL1,FYB1,PHYHIPL,MEGF10,GABRA2,GAD1,GALR1,ZNF559,SYT17,NTNG2,LNX1,GPM6A,MCHR1,GRIA4,GRIK3,GRIN1,GRIN2C,NR3C1,GRM2,GRM7,PTPRT,GSTM5,GSTT2,SOX21,GUCY1A2,MAEL,PADI2,GPR45,FRMD5,HLF,ZNF491,USP51,HTR2A,IRF8,KIT,LAMA2,LIG4,MATK,MATN3,MBP,CHST6,MN1,JAKMIP3,MT3,MYCN,FXYD7,NCAM1,NEFM,NEFH,NELL1,NEUROD2,NPTX2,NTRK3,NUCB1,PENK,CYTL1,ABCB1,GDAP1L1,PIK3CD,PIK3R1,PLCB2,JAKMIP1,TRHDE,PPP1R1A,HYDIN,DIRAS2,MASP1,PTPN13,PTPRG,PTPRO,PTX3,RAP1GAP,RASGRF1,BEND5,KHDRBS2,RET,FIGN,RFX4,ZDHHC4,ZNF671,RIMKLA,HUNK,CCDC112,SALL1,ATXN1,SCP2,HES6,SEC14L1,GALNT10,SH3GL2,FERMT1,ST6GAL1,SLITRK3,DZIP1,ZNF365,SLC8A3,TMEM132D,ELMO2,SPHKAP,INAVA,SNRPN,SOX2,CLSTN2,CAMTA2,SST,SSTR2,MPRIP,STAC2,FNDC9,SYP,ASTN2,TAC1,PCDHGB7,NAT16,TMEM121,HHIP,TIE1,TIMP4,PRRT1,LILRA4,IL34,CHST5,TRH,TRIO,RUNDC3B,TMEFF2,FLRT2,VLDLR,KCNK12,ZIC1,ZIC3,ZNF19,ZNF23,MICU3,TRIM9,ZNF154,FSTL5,DPYSL5,PRDM2,PLD4,DNAH10,SSPN,NETO1" Drug ctd:C045362 prochloraz CTD 8.49E-13 4.16E-08 3.96E-10 4.51E-09 89 268 "ACTN1,LRRC7,SRPX,DOC2A,DPP10,ASTN1,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CAMK2B,CAMK2G,CBR1,CD81,CHGA,DLGAP3,NRXN1,NRXN2,NMT2,ABCG2,CRHBP,CSNK1E,DCC,MAGI2,KLHL3,DLG4,DYNC1I1,DPP6,KLHL5,CACNG7,EGFR,ERBB2,ERBB4,CACNG2,FYN,GABRA4,GABRB1,PPARGC1A,GLS,FUT10,STMN2,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,IL1RAPL1,AGBL5,HSD17B1,IGF1,JAK1,LSS,ERICH3,N6AMT1,NF1,OTOGL,NRCAM,NTRK2,ABCB1,GDAP1L1,TNPO2,RELN,MDGA2,ACSS3,ENOX1,RET,ZFHX4,ROBO1,RXRA,HES6,NLGN1,SLC1A2,SLC1A6,SLC6A11,SHANK2,SLC12A2,SLIT1,IFT122,UNC5B,MPRIP,STXBP1,SYP,TMEM121,TSC2,CADM1,RGMA,IFT88" Drug 4139_DN Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.33E-13 4.57E-08 4.23E-10 4.82E-09 72 198 "DPF1,ACTN2,ADORA1,MRTFA,TRMT9B,AMPH,APBA2,PPP4R4,ARSE,ADAM23,RGS9,CFLAR,KSR1,CACNA1I,LDLRAD4,CFAP410,CAMK2B,RUNX1T1,SLC16A4,SCARB1,PICK1,AKAP7,GREB1,NOS1AP,DBT,HS3ST2,EFNB3,EGFR,ELN,STX2,KIAA1109,CAMSAP1,FHL1,HPCAL4,C1orf61,SORBS1,GAP43,ALDH1L1,POLL,LPAR4,PCLO,GRM7,HAS2,HLF,HMGB1,ITIH2,KCNB1,KCND3,MAP4,TAGLN3,NELL2,NEUROD1,SERPINI1,PLCD1,PTPRO,RAB3IL1,ZMAT4,ZFHX4,SEMA6D,ASAP3,SLC9A5,BTBD7,PLCB1,TBCEL,PCDHGB6,PSD3,PCDHA5,RIMBP2,VIPR2,XRCC4,NUP214,DPF3" Drug 6843_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.33E-13 4.57E-08 4.23E-10 4.82E-09 72 198 "SEMA6A,SEMA7A,APLP1,APOC1,LGR5,MARK4,SCAPER,CACNA1I,BAIAP3,CACNB4,HAP1,ARHGEF1,ADGRG1,TAOK2,VAX2,CNN3,PICK1,CPS1,NCOR2,ARHGEF10,CHD5,CNTNAP2,DCAF4,MAML1,DGKG,RABGAP1L,DYRK1A,SORBS3,ACSL4,ZNF589,KIAA1109,FHL1,C1orf61,FYN,SRCAP,GFER,GRIN1,GRM1,GRM8,AP4S1,RASSF8,KCNMA1,KCNQ3,MID1,NPTX2,SNTG1,ENPP2,POU3F4,MINDY2,PRKAR1B,MAPK7,CEP97,TCP11L1,EMID1,RYR1,SELL,RASA3,ASAP3,CCDC88A,SLCO1A2,ZCCHC24,TSNAXIP1,CLSTN2,AJAP1,MLC1,ZFR2,VAMP1,WSCD1,UGT8,VLDLR,SPHK2,NT5M" Drug 1490_UP Diflunisal [22494-42-4]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.33E-13 4.57E-08 4.23E-10 4.82E-09 72 198 "NME5,C1QTNF3,SPARCL1,MRTFA,BIN1,CDC42BPA,KCNAB2,CDC14B,PLA2G4C,ALDH4A1,ALDH7A1,CFLAR,KSR1,SCAPER,BTRC,CDH8,SLC24A2,AKAP7,RIMS2,GPRASP1,ARHGAP24,KBTBD11,MBNL2,CEND1,PTK2B,ZNF589,FGFR1,BAIAP2,HPCAL4,PDLIM5,OGA,TRAF3IP2,SEPT9,SRCAP,PCDH17,C1QL1,PRUNE2,HNMT,INPP5B,ITIH2,LMO2,MBD1,MEF2C,MSI1,ZNF862,NPTX2,NUCB1,SETD4,PIK3CD,NLE1,PLCD1,PRODH,PTHLH,FRMPD1,ASAP3,BCAN,SLC1A7,PEX26,FAM214B,SLC11A1,SNCA,DOK5,ANKRD12,WSCD1,PCDHGA10,CRTC1,CHST8,THBS4,TMOD1,PIK3R5,TPD52,VIPR2" Drug ctd:D000431 Ethanol CTD 9.61E-13 4.71E-08 4.32E-10 4.92E-09 359 1620 "ABAT,ACADM,ACHE,ACLY,AS3MT,ADCY2,ADCY5,ADCY6,ADCY8,TMCC3,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AP1B1,AGT,ALAD,AMPD3,AMPH,BIN1,PPFIA4,APAF1,GPAM,BCAS1,APP,AQP4,ARHGAP5,ARHGDIA,ARRB1,ARRB2,ASGR1,RASL11B,ATM,ATP1B3,ATP2B1,ATP2B2,ALDH7A1,AZGP1,MPDZ,CFLAR,BMP7,IL33,MMD2,CA4,CA8,CACNA2D1,CALB1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,RHBDL1,CBLN1,CBS,KYAT1,CCK,RGN,MTMR7,P2RX6,AIFM1,SCARB1,CDK11B,CDC25B,CDC42,NRXN3,CLU,FADS2,ABCG2,RAB26,CNN3,CNR1,SLC4A8,GAL3ST1,COX4I1,ZNF521,CPS1,CREM,SH2B1,SLC32A1,ABCG1,CRYM,CS,GALNT9,PDE4DIP,ERC2,CMTM5,CTH,CYBB,HDAC4,DAPK3,DBN1,NTM,AK5,FAM107B,DLG4,GRIN3A,MED12,CDON,DNM2,SLC25A18,DRD1,ATN1,DTNA,ST8SIA3,SNX29,EDN1,EDNRB,EEF1D,EGFR,EGR3,HSD17B14,PLEKHO1,MFSD10,RASGRP2,GPHN,NCALD,NRN1,F3,CLVS1,FABP7,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,RACK1,FCGRT,FDFT1,PPP1R1B,FGF1,ATP5PD,FOXO3,FLNC,FLT1,ZNF605,ADGRA1,FYN,GABRA1,GABRA2,GABRA3,GABRA4,GABRB1,GABRB3,GABRG2,TRAF3IP2,ILDR2,GAD1,ARPP21,GAP43,ALDH1L1,GCNT2,GFAP,GFRA1,CSDC2,GHR,PPARGC1A,DHRS4,GLDC,GLRB,GLUL,GNAL,GNAO1,GNG3,GPD1,GPD2,TUBA1C,GRIA1,GRIA2,GRIA4,PLCD4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,ADAMTS8,GRIN2C,GRIN2D,NR3C1,GRM1,GRM3,GRM5,GRM7,GRM8,FAM107A,SLC2A6,NXPH3,PACSIN2,ELOVL5,HMGB1,HMGCR,HNRNPK,HPCA,OPALIN,HSD17B1,HSF2,HSPA1L,HSP90AA1,SMAP1,IDH3A,SOWAHA,IGF1,IGFBP1,IGSF1,IL6R,IL12A,TUBB2B,JAK1,KCNA1,KCNC2,KCNH2,KCNJ3,KCNMA1,KIFC3,L1CAM,LAMP2,LSS,MAP2,MAT2A,MATN3,MBP,SYT9,CHIC1,MT3,SCG3,MTTP,MTR,MYH3,MYL3,FXYD7,NAP1L1,NCF2,NDUFA5,NEFH,NFE2L2,NFIX,NME4,NOS1,NPY,NPPA,SLC11A2,NRCAM,GPR88,OGDH,OGG1,OPCML,PDE3B,PDE4A,PDE4B,PDE4D,ENPP2,PDYN,PENK,PFKFB4,SERPINE2,PIK3R1,PLCD1,PLCL1,PMP22,PSAT1,PMS2,POLR2F,PPARA,PPP3CA,PPP3CB,PPP3CC,PRKACB,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,MAPK9,PTCH1,PTHLH,ELOVL2,STK32A,CASTOR1,PTPRO,NKAIN1,RAD17,RET,PCMTD2,RXRA,STX1B,RXRG,S100B,SAFB,MAPK12,SCP2,SGK1,NTNG1,WDR37,ABLIM3,SLC1A2,SLC1A3,SLC1A6,RPH3A,SLC6A7,SLC6A9,SLC8A3,SIRT2,EFHD1,SLC20A2,TET1,OGDHL,SNAP25,SNCA,MYT1L,KDM3A,SPP1,ZC3H13,DDN,LHPP,SSTR1,SEPT8,PHLDB1,STX1A,STXBP1,NSFL1C,VAMP1,DNAJC9,ARC,SYP,TAC1,TAF6,PDLIM2,AGTPBP1,SYNE1,TF,SIRT1,HHIP,TJP1,DDHD1,TLR4,CDK20,TRH,PRR18,CADM1,UCHL1,DNAJC12,CCDC136,VLDLR,RBFOX3,ZIC1,FMN2,ZBTB16,DPYSL5,SLC30A3,TUBA1A,SLC17A7,TMEM163,SLC17A6,FZD3,GJC2" Drug 3243_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.19E-12 5.85E-08 5.31E-10 6.05E-09 66 175 "ADD3,NME5,SEMA6A,BMP7,ST3GAL5,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,RASGRP2,STX2,TUBB4A,HPCAL4,DPYSL4,FYN,CYP46A1,RND1,RAB40B,STON1,DIPK1A,KIF5C,VWA5A,MITF,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PLCD1,PMP22,PKIA,PRPH,LRRC49,SH3GL3,PPM1E,ASAP3,SYBU,ZNF365,WDR47,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,ZEB1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,REEP1,NAV2,SLC17A7,ITM2C" Drug 4485_UP Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-12 6.07E-08 5.42E-10 6.17E-09 72 199 "ADD2,ADGRF5,APAF1,APBB2,EPB41L5,PRX,BMP7,FUBP1,GYG2,KALRN,LHX2,STOML1,CLTB,FAM189A2,CNTFR,COL9A2,TCEAL2,HAPLN1,CSF1,FRMPD4,SMG7,DMD,ATN1,DTNB,ABCC9,EDIL3,CELSR3,TENM1,ETV1,ARMCX1,DLC1,KAT8,KIAA1109,DPYSL4,NSG1,ZNF44,ZNF276,GLS,GNAL,PRUNE2,RAPGEF1,GRIK5,GUCY1A2,KLF12,HLF,MAN2A2,ADAM22,NPPA,PFKFB2,EPN1,MAPK7,ZSCAN32,RET,RGS4,MYH14,SCN2A,SCN8A,CNKSR2,SLC1A7,SHANK2,RIMS1,SPTAN1,LHPP,TNS1,ZMYND8,VAV1,VGF,SPHK2,ZBTB38,ZNF225,HPS4,JPH3" Drug 5906_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-12 6.07E-08 5.42E-10 6.17E-09 72 199 "ADCY2,AP2A2,AMPD3,APBB2,APOC1,MARK4,CADM3,HAP1,CCKBR,SEPT7,LHX2,SULT4A1,CNTN1,RIMS2,RASSF2,RIMS3,DAPK3,ING4,ELAVL3,RASGRP2,MTSS1L,CACNG3,ATP8A1,FCGRT,FGF13,FGR,AGAP2,GAP43,CPLX2,AHDC1,C1QL1,RND1,GRM1,SHISAL1,TJAP1,KCNH2,KCNJ4,LAMA2,MAOB,MID1,ZNF862,CNOT4,NOVA1,OPCML,KCNK10,PIK3CD,MAPK7,SAMD9,ENOX1,RFX2,MYH14,PNMA8A,KCNIP2,SLC1A7,CXXC4,TNIK,ZCCHC24,NMNAT2,ZC3H13,ATP10B,COLGALT2,SAMSN1,PHLDB1,AJAP1,DOCK9,TMEM151B,HEY1,TMPRSS5,OSBP2,SLC17A7,MVB12B,EPM2A" Drug CID000002207 2-amino-4-phosphonobutyric acid Stitch 1.51E-12 7.41E-08 6.55E-10 7.46E-09 43 91 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,BCS1L,BSN,WASF1,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CARS,SLC32A1,EEF1A2,GLRB,GRK4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,GPSM2,RYR1,SLC6A1,SPP1,SYN1,SYN2,SYT1,TSN,SLC30A3" Drug 2639_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.64E-12 8.05E-08 7.04E-10 8.01E-09 67 180 "ABHD6,ARID1A,ADD3,ALCAM,MARK4,ALDH4A1,ST3GAL5,CLGN,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,TMCC2,GNE,TSPAN5,FRY,EFNB3,MBNL2,TUBB4A,ATP8A1,DPYSL4,FYN,ALDH1L1,CYP46A1,RND1,GLS,STON1,GPR37,KCNA1,KCNN2,KIF5C,MITF,MXI1,PCDH9,SERPINI1,PIK3CD,RETREG1,PLXNB1,PKIA,PRPH,RAB3A,RPS6KA2,SH3GL3,PPM1E,ZNF365,WDR47,FAM214B,ZCCHC24,SPTAN1,NPAS3,ELOVL4,CEP68,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C,SMIM8" Drug 6934_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-12 8.12E-08 7.04E-10 8.01E-09 71 196 "SEMA6A,LTBP4,ALDH7A1,BMP7,SCAPER,RAB29,SYNGR3,ARHGEF10,GREB1,GAPVD1,BRINP1,DBN1,ARMCX2,CDON,GNE,OPTN,EFNA3,SUGP2,EML1,EPB41L2,F8,ARMCX1,EFEMP1,FGFR1,GPR153,FYN,SYT17,MALT1,RUNDC3A,GPR37,ELOVL5,INPP1,KCNH2,KIF5C,KPNA5,MATK,MEIS1,MPP2,PDE4A,PHKG1,PLTP,POLG,MAPK7,MAPK8,PTPRE,ZDHHC14,SEC61A2,MAPK12,SEC14L1,SUPT20H,ZFP30,SYBU,ANKRD6,SLC6A8,SNCA,KDM4B,WDTC1,ZHX3,IQSEC2,ELOVL4,STX1A,PLCB1,SIK3,TMPO,PLPPR2,VLDLR,REEP1,EMSY,KCNAB1,WIPF2,RNF170" Drug 5206_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.67E-12 8.16E-08 7.04E-10 8.01E-09 70 192 "NME5,SRPX,APC,APLP1,PPFIA3,PDXK,MARK4,ASPH,BMP7,ST3GAL5,GYG2,RAB29,HAP1,ARHGEF1,SYNGR3,CLGN,LHX2,SULT4A1,ABCG1,FAM169A,SDC3,DBN1,ARMCX2,EFNA3,EFNB3,EML1,ENO2,REEP2,ZNF589,KIAA1109,FGF12,FYN,GAD1,RUNDC3A,STON1,GRB10,GSN,KCNH2,KCNN2,KIF5C,MPP2,ADAM22,PCDH8,TMOD2,SERPINE2,PTCH1,RAB3A,RALGDS,C1orf54,SEC61A2,ZNF821,ASAP3,ZNF365,FAM214B,ARHGEF40,WDTC1,TNIK,ZCCHC24,NMNAT2,ELOVL4,FAM168A,WSCD1,BEX4,PARD3,UCHL1,DNAJC12,VLDLR,LAT2,NDRG4,MAP3K12" Drug CID000005114 3-(1H-pyrrole-2-carboxylate Stitch 1.72E-12 8.41E-08 7.18E-10 8.17E-09 80 233 "SLC24A4,AK2,ANK2,APP,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,CANX,CCK,KRIT1,CD38,LRBA,CHRM1,SLC24A2,HOMER3,AKAP6,CABP1,AKAP5,MYEF2,DMD,EDN1,EDN3,EDNRA,SPSB4,SCARA3,CAMKK2,ATP2C1,GCNT2,KCNMB4,RAPGEF4,GRIA1,GRIA2,GRIA4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1B1,SCRT2,KCND2,KCND3,KCNH2,KCNMA1,KCNN3,MAG,MYBPC1,MYH6,NPPA,NPR2,CAMKV,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,QDPR,RYR1,RYR3,SLC8A2,SLC8A1,SNAP25,WDTC1,CABIN1,TRPM2,CAMK1G,NUP214" Drug ctd:D002737 Chloroprene CTD 2.04E-12 9.99E-08 8.47E-10 9.63E-09 308 1355 "SLC25A25,FMNL2,KLHL32,CCDC85A,ADD3,PWWP2A,MTUS1,PCDH19,NME5,BCAR3,AMPD2,AMPD3,CDC42BPA,SEMA7A,APBB2,EPB41L5,DGKZ,APOC2,SHROOM2,ARHGAP5,ARNTL,ASGR1,MARCH3,STK33,SLC4A4,ATP2B2,MTMR9,NRP2,PROM1,IL33,CACNA1D,CH25H,SPAG9,RUNX1T1,CBR1,KRIT1,USP2,CD38,CDH2,LARGE1,ZNF445,CDO1,LRWD1,NOG,UBE2L6,SRSF11,CBARP,RAB3C,JAM2,NRXN1,FAM189A2,ABCG2,HECTD1,MAP4K4,LY86,CCDC151,CNR1,ARMC8,MYRIP,ZNF521,ZFP28,MFSD4A,NECTIN3,PNKD,RBM39,AKAP12,NCOR1,CRYM,CSF3R,LRRC3B,MICAL2,IPCEF1,DZIP3,PHF14,CTH,PUM1,CYBB,DOCK4,HDAC9,KATNAL2,GAPVD1,RIPOR2,DGKG,DAPK1,PITPNC1,ARMCX2,ZEB2,RHOBTB1,SV2B,NR1D2,CPEB2,CASP8AP2,ABI1,DTNA,EBF1,WDPCP,EDNRB,HIPK3,RASGRP1,KLHL5,TMTC1,RBM12,FAM13A,PHF20L1,EGFR,EGR3,KCTD3,EIF4G1,EIF5,PLEKHA1,SRPK3,ELN,CALCRL,EPB41,LRRC23,NCALD,ETV1,RASL12,F3,F5,TMEM132C,DLC1,FCGR1A,ZMYND10,BAIAP2,FGR,MEX3B,HPCAL4,FOXF2,IQCG,FOXO3,EVL,SEMA4D,FLT1,SORBS1,TMEM107,AK8,CAMKK2,ST6GALNAC3,FYB1,SDCBP2,GALNT15,MTHFD2,GFRA2,PCDH17,PPARGC1A,LYVE1,RND1,GLUL,ZNF638,GNAS,GPT2,PSRC1,LILRB4,GPD2,GPR34,EML4,RAPGEF4,PRDM5,FAM107A,GUCY1A1,GYG1,TOX2,LRRC75A,IRF8,IFI16,IGF1,KNDC1,IL12A,TUBB2B,ITGAM,ITIH2,KCNA6,KCNK1,LMO2,PIK3AP1,MAT2A,MBD1,MEF2C,KITLG,MN1,MYCN,NEK1,NFIA,NFIX,NRCAM,DDR2,PCSK1,PCSK5,GNG2,PFKFB3,ABCB1,SERPINE2,PIK3CD,CCSER2,GPSM2,PCDH18,PRRX1,PILRA,SH3KBP1,MED1,MINDY2,LRRN3,PRKCB,MAPK8,PRODH,GDPD1,MASP1,SAMD9,GDPD2,QRICH1,PTHLH,PTPRD,PTPRE,PTPRO,MARCH1,FAT4,ARID4A,RBBP6,SLC6A15,RGS4,TTLL7,PBRM1,ZFHX4,SETD5,ROBO2,ZC3H14,PRR5L,MEG3,KCNIP3,CLIP1,SATB1,ATXN7,SCN3A,TNFRSF19,ELMOD1,SELL,SFPQ,SLA,SLC1A3,PREX2,PKNOX2,RADIL,EFHD1,TET1,SMARCA4,LIMCH1,FAM126B,PDZRN3,SCN3B,SOX2,TNIK,KIF21B,TSNAXIP1,SOX11,SPP1,ZC3H13,SRPK2,TROVE2,POGZ,SAMSN1,ANKRD12,DDHD2,MCF2L,ADGRL3,TMEM136,WSCD1,TCF4,WASHC4,SZT2,ARHGAP9,HIF3A,HHIP,CDH22,ARL10,THRA,TIAM1,TIMP4,ZFP91,ERCC6L2,ZNF346,SYNPO2,PRMT8,TRIO,TRPS1,TTC3,UBE2H,UBE3A,UCHL1,VAV1,TSPAN11,RBFOX3,WNT7A,CFAP52,ZBTB16,EMSY,MFF,DNALI1,PRDM8,TMEM178A,MDH1B,NAV2,SNX27,PLD4,KAT6A,FBXO36,ZDHHC20,ST8SIA2" Drug 6423_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-12 1.08E-07 8.97E-10 1.02E-08 71 197 "ARID1A,NLGN4X,TRMT9B,APOC1,ARNTL,N4BP2L1,PROM1,SYNJ2,SCAPER,BAIAP3,CA4,CACNB2,CALB1,RCBTB2,RAB33A,PLAA,AKAP7,FAM149A,CHD1L,IPCEF1,RIMS2,EDRF1,SHANK1,DTNA,EDNRB,SEMA3D,F5,ANKFY1,AFF2,GABRA5,GABRB1,ATP8A2,GPM6A,ATF7,GRM3,GUCY1A2,KLF12,SCRG1,HTR2A,IL11RA,KCNJ3,MMP16,CD200,NEUROD1,PCDH9,CDK14,PRRX1,MAPK8,PTCH1,PTX3,C1orf54,RGS4,ATXN7,SCN3A,SH3GL2,FRMPD1,ZCCHC24,EMC1,NPAS3,ATP10B,JMJD6,CUX2,TRIM2,PCDHGB6,SEZ6L,ZMYND8,LAT2,SLC30A3,ADAMTS9,PLSCR4,PHTF2" Drug 3195_UP Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.20E-12 1.08E-07 8.97E-10 1.02E-08 71 197 "FZD9,ALCAM,FAM135A,APAF1,APC,APP,ARHGDIG,AZGP1,CFAP410,KCNAB3,DLGAP2,B4GALT6,COL9A3,CNTNAP2,NOS1AP,PHYHIP,CNIH3,MFAP3L,RUSC2,DTNA,DUSP9,ST8SIA3,EDNRA,C3orf18,NCALD,DLC1,FLT1,FYN,GABRA5,PCDH17,GLYR1,TOX3,GRM3,GPR45,VWA5A,SMAD1,MATN3,AFF1,MMP17,MOBP,CD200,MYT1,PALM,PDE4D,ENPP2,PLCB2,CDIP1,POU3F2,CCDC40,RFX2,RIT2,ZFHX4,OGDHL,SNAP25,MYT1L,SP4,DDN,ARC,SYN2,ADGRL3,HIF3A,TGFBR3,DAAM2,VGF,XRCC4,ZNF45,PRDM2,GDPD5,SCG2,NUP214,SSPN" Drug 989_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.23E-12 1.09E-07 9.01E-10 1.03E-08 69 189 "CDC14B,KIF1A,ST3GAL5,SCAPER,GYG2,SGCE,RAB29,KYAT1,SYNGR3,CRLF1,ADGRG1,FOXN3,WHRN,ABCG1,PDE4DIP,RASSF2,RIMS3,DBN1,ARMCX2,OPTN,EFNA3,EFNB3,EGFR,SORBS3,ENO2,DPYSL4,GPR153,CSPG5,FYN,ZNF44,HBS1L,SYT17,ATF7,STON1,SLC2A6,KCNH2,KCNN1,KIF5C,LMO2,MAPT,ZNF862,NPTX1,PALM,PDE4A,PIK3CD,MAPK8,PRPH,CNNM2,PTCH1,RALGDS,FAM184A,ZDHHC14,RPS6KA2,RPS20,ZNF821,ASAP3,LIMCH1,ZCCHC24,MAPK8IP3,STXBP1,TRIM2,PCDHA5,BEX4,CABIN1,DNAJC12,VGF,MICAL1,REEP1,MAP3K12" Drug CID000000892 myo-inositol Stitch 2.45E-12 1.20E-07 9.82E-10 1.12E-08 203 812 "ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,AMPH,DGKZ,DGKD,NT5C3B,ARRB1,ARRB2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,SYNJ1,SYNJ2,BTK,MTMR3,MTMR2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,CAMK2D,SPAG9,CCK,CCKBR,SLC5A11,P2RX6,ARHGEF1,CD38,DGKI,LRBA,CACNA2D2,CHGB,CHRM1,PLEKHB1,CHRNA4,CLTC,HOMER3,CSF1,RGS6,CALY,PLCXD3,DGKB,DGKG,IP6K1,PITPNC1,SNAP91,DNM1,DNM2,DNM1L,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,RASA4,LPAR6,BSCL2,EPB41L1,ERBB2,ERBB4,CACNG2,PTK2B,FCGR1A,FCGR3A,FGF1,FGFR1,IP6K2,AGAP2,FOXM1,FOXO3,PSD2,ATP2C1,B3GAT1,FYN,GAA,GAB1,GALR1,IP6K3,IQGAP2,GFRA1,GNAL,GNAO1,GNAS,GNG3,ADAP1,LPAR4,MCHR1,GRB10,PLCD4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GSN,SLC2A6,GPR45,HRH3,HTR2A,MYLK2,IGF1,INPP1,ITPKA,ITPKB,LIG4,MATK,MBP,KITLG,MMP17,P2RY13,NF1,NPY,OCRL,OPCML,OXTR,P2RX7,P2RY1,PDE3B,PDGFRA,PDPK1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,PLCD1,PLCL1,POLR2F,PPP1R1A,CRLS1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTAFR,PTHLH,PTH1R,RGS3,RGS4,RGS7,RGS10,RPL38,RYR1,RYR3,MAPK12,SMPD3,RASA3,SLA,TEX2,SS18,PLCB1,TAC1,TAC3,ATP11A,TACR1,TBL1X,TCF4,PIK3R5,TRH,PDSS1,TRPC1,TRPC3,NTSR2,TSC1,PITPNB,FLRT2,VAV1,VIPR2,P2RY12,RICTOR,ETNPPL,PLPPR5,PLD4" Drug 4343_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.90E-12 1.42E-07 1.15E-09 1.31E-08 71 198 "ASPHD1,ACTN2,FAM135A,APAF1,CDC14B,CDK10,PPP4R4,ASPH,RASL11B,CADM3,N4BP2L1,BCL7A,CACNA1I,CFAP410,STOML1,AKAP6,CYBB,MAML1,RABGAP1L,DSCAM,EDN1,LRRC17,KCNMB2,CAMSAP1,FLT1,DPYSL4,DENND2A,GAD2,HBS1L,ERAP1,GPM6B,GPR19,SOX21,PADI2,AGFG1,HTR2A,ICA1,KIF5C,TM6SF1,MMP16,NELL2,NOVA2,NPPA,NPR2,NTRK2,NUMA1,PBX1,PDGFRA,PIK3R1,STRN3,POU3F4,MAPK8,CCDC40,RGS4,KIRREL1,TMEM206,SH3BP2,CPEB3,ZNF334,ZNF667,SP4,HECW1,IQSEC2,RBM26,THRA,TUBB1,SF1,WNK1,NT5M,KCNAB1,KAT6A" Drug 5207_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.90E-12 1.42E-07 1.15E-09 1.31E-08 71 198 "KIDINS220,NME5,APC,PPFIA3,APP,AQP4,MARK4,N4BP2L1,BCL2L2,CFLAR,KSR1,GYG2,CACNA1I,BAIAP3,USP2,ARHGAP33,NCOR2,CNTNAP2,SDC3,PHF14,PARD6A,ATN1,SIDT2,EFNB3,EGR3,ELAVL3,EN2,EPHB1,CAMSAP1,TRMO,GAP43,ADAMTS13,GRM7,GRM8,GSTM5,GUCY1A1,KCNB1,KCNN1,MAOB,NOS1,NOVA2,NTRK2,OPCML,PFKFB2,MAPK8,SNRK,PTHLH,RAB3IL1,ZCWPW1,RGS12,RNASE1,TMEM206,SYNDIG1,BCAN,PEX26,CXXC4,SNAP25,SOX3,SOX10,ZC3H13,MAPK8IP3,RGL1,PHLDB1,PLCB1,ARC,SYN2,ATP11A,ARHGEF12,TPM2,CHST5,SSPN" Drug 5693_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.95E-12 1.44E-07 1.16E-09 1.31E-08 66 178 "ADD3,NME5,ST3GAL5,SGCE,BAIAP3,CLGN,AKAP12,PDE4DIP,DOCK4,RIMS3,ARMCX2,DNAJC6,MAGI2,EFNA3,EFNB3,FAM13A,STX2,TUBB4A,ATP8A1,FHL1,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,TDRKH,STON1,RNFT2,KIF5C,VWA5A,MXI1,NAP1L3,SERPINI1,PIK3CD,RETREG1,GRAMD1C,PRPH,RAB3A,NUDT11,RPS6KA2,SH3BGR,SH3GL3,WDR47,FAM214B,PKNOX2,OGDHL,SOX15,PEG10,THSD1,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 2514_UP Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.82E-12 1.87E-07 1.45E-09 1.65E-08 71 199 "ADD2,AGT,ANK3,CNTNAP1,APAF1,CDC14B,B3GALT2,FGF17,BMP7,CA12,HIP1R,ARHGAP33,SOCS6,NRG2,ATRNL1,DCAF4,RUSC2,OPTN,ING4,SRPK3,COQ7,FAM198B,ST3GAL6,FER,FHL1,FOXG1,AGAP2,PDLIM5,OGA,GAB1,GABRA4,ZNF44,GABRA5,SIGLEC8,CSDC2,GNAS,GPR19,PCLO,GRIK4,GRM8,GSN,FAM107A,PADI2,HRH3,KCNN1,MMP16,TAGLN3,NCAM1,NF1,P2RY1,POU3F4,PRKAR1B,PTAFR,PTPN13,MARCH1,KCTD17,TMEM206,SH3BGR,ASAP3,IZUMO4,ACSBG1,TAL1,WWC1,WSCD1,PCDHA5,TEX15,TMOD1,TMPRSS5,FAM155A,LMF1,SLC17A7" Drug 3226_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.82E-12 1.87E-07 1.45E-09 1.65E-08 71 199 "SYN3,ABHD6,ARID1A,SEMA6A,SEMA7A,PPFIA3,SEMA4G,PRX,ATP6V0A1,BMP7,ST3GAL5,BTRC,CA4,SLC16A4,ARHGEF1,CHM,CNTN1,SNCAIP,SIPA1L1,CYBB,DCAF8,MFAP3L,EXOG,RCAN1,EGFR,PLXNC1,ING4,RASGRP2,FHL1,C1orf61,IQCG,PRELID3A,HBS1L,SIGLEC8,GFER,RND1,ADAMTS13,INPP5B,ITGA7,KCND1,KCNN1,MATN3,NTRK2,PDE1C,LRP12,MBOAT7,PTHLH,ATG16L1,RGS12,ZFHX4,SUGCT,KLHDC8A,ASAP3,PEX26,SLC6A8,BTBD7,SLC22A4,TSNAXIP1,HECW1,SAMSN1,ACSBG1,SMG6,ICAM5,HEY2,TNS1,TPM3,LAT2,SLC30A3,DNALI1,MVB12B,FAM13C" Drug 2201_UP Foliosidine [2520-38-9]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.82E-12 1.87E-07 1.45E-09 1.65E-08 71 199 "ARID1A,BCAR3,BEGAIN,TRMT9B,BMP7,HAP1,REPS2,CDH2,KCNAB3,CHN2,ZFYVE9,SLC24A2,ARMC8,SLC4A8,PDE4DIP,RIMS2,EDRF1,CTIF,SMG7,DSCAM,EFNB3,SORBS3,ST3GAL6,CAMSAP1,FLNC,FLT1,EFCAB2,DLL3,GABRA4,TRAF3IP2,ZMYND11,INPP5K,ADAM28,RUNDC3A,GRM1,GRM7,TJAP1,KCNJ5,KHK,MYCN,NNAT,OPRL1,SLC25A23,MASP1,BCAS3,FAM120C,SUGCT,FBXW7,SLC1A7,PKNOX2,SNCA,TMCC1,SS18,ACSBG1,ADGRL3,SYNE1,HIF3A,BHLHB9,TMOD1,PARD3,TNNT1,TPM2,RPRM,VAV2,SH3GLB2,ZNF225,SLC17A7,KCNAB1,PAK5,KAT6A,NLRP3" Drug 4193_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.82E-12 1.87E-07 1.45E-09 1.65E-08 71 199 "NME5,N4BP2L1,NRP2,SCAPER,HAP1,CDC42,LARGE1,MAGI1,ABCG2,HOMER3,CNTN1,PCYT1B,IFFO1,CNTNAP2,CTNND2,DMD,ST8SIA3,SIDT2,ING4,TNK2,CORO2B,ZNF589,KIAA1109,FGFR1,IQCG,FLT1,PDLIM5,GAB1,ZMYND11,MSTN,PCDH17,TDRKH,GRM1,GSTM5,PTGDR2,KCNJ3,LAMA2,SHC3,NF1,NTRK3,PDE2A,PDGFRA,PLPPR1,ELOVL2,ZSCAN32,ACSS3,SH3TC2,ENOX1,STUM,SUPT20H,ST8SIA1,DZIP1,PREX2,SNCA,RBM34,TNIK,KIF21B,ZC3H13,BEX1,TROVE2,INKA2,ACSBG1,RPGRIP1L,CHST8,TK2,DAAM2,TNS1,TUBB1,VAV2,SLC17A7,FZD3" Drug 5977_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-12 1.90E-07 1.45E-09 1.65E-08 70 195 "ALAD,SHROOM2,ADGRB2,ST3GAL5,SYNJ2,CACNA1I,BTRC,SYNGR3,ARHGAP33,RAB28,CLCN4,DNAJB5,ABI3BP,ABCG1,PDE4DIP,CNTNAP2,EXOG,DSCAM,DTNA,EDIL3,HIPK3,FCF1,SEMA3D,MBNL2,EIF5,RGS17,ERCC2,EFEMP1,DLC1,ATP8A1,C1orf61,FLT1,GAD1,POLL,TDRKH,GPR37,CNTRL,GRM1,PADI2,IGFBP1,KCND3,LSS,MMP16,NFYA,PCDH9,PDGFRA,RETREG1,MAPK7,TMEM104,CARF,GSTCD,NEK11,ST6GAL1,BTBD7,WDTC1,SPTB,LHPP,SYT1,ASTN2,OBSL1,ZFPM2,TMOD1,TMPO,R3HDM1,TRPC1,LAT2,SPHK2,NAV3,MVB12B,GAN" Drug 2504_UP Skimmianine [83-95-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.89E-12 1.90E-07 1.45E-09 1.65E-08 70 195 "ACHE,ADCY2,ALK,BIN1,SEMA7A,APBB2,EPB41L5,SEMA4G,PDE8B,ATP1A3,AZGP1,FUBP1,BAIAP3,CDK5R2,BTRC,CACNG1,CBFA2T2,DLGAP1,EPS15L1,RAB33A,ABCG2,NCOR2,RGS6,RIMS2,HS3ST2,ST8SIA3,EDN3,EDNRA,AASS,DLC1,SORBS1,ZNF44,DENND2A,GAD1,GAD2,ARPP21,GLI2,GLYR1,GRIA4,KCNJ3,KCNJ4,MAG,MOBP,TAGLN3,MYO6,NOS1,KCNK10,ABCB1,PKIA,TCP11L1,KCNIP2,LIMS2,SLC6A1,SHANK2,SLCO1A2,SLN,PDZRN3,SOX2,SOX11,SPTB,CLSTN2,MAPK8IP3,PLCB1,TRIM2,TEX15,PRMT8,FAM155A,KCNK12,ZIC3,ZBTB16" Drug 5903_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.96E-12 1.94E-07 1.46E-09 1.66E-08 66 179 "DPF1,ADD3,NME5,SEMA6A,APAF1,BAIAP3,CDK5R2,CDH18,CLGN,WHRN,AKAP12,CRYM,PDE4DIP,SEC14L5,ARMCX2,DNAJC6,FRY,FAM13A,TUBB4A,DLC1,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,GLS,RAB40B,TDRKH,STON1,KCNB1,VWA5A,MAP2,MXI1,NAP1L3,PCDH9,ENPP2,TMOD2,SERPINI1,PIK3CD,RETREG1,MAPK8,PRPH,RAB3A,RADX,NUDT11,RPS6KA2,SH3GL3,WDR47,PKNOX2,ZCCHC24,KIF21B,SOX15,ARHGAP26,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,SYN1,ZEB1,HEY1,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 6709_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.96E-12 1.94E-07 1.46E-09 1.66E-08 68 187 "ABAT,ADRB2,CDC14B,ARNTL,MARCH3,ST3GAL5,SCAPER,USP2,CHN2,ABCG1,PDE4DIP,CTH,DNAJC6,JAKMIP2,MFAP3L,C2CD2L,PLPPR4,FAM13A,RGS17,RASGRP2,TAOK3,ATP8A1,DPYSL4,NBEA,SORBS1,FYN,CYP46A1,PCDH17,GLS,STON1,GPR22,GRIK2,ICA1,DIPK1A,INPP5B,KIF5C,LIFR,VWA5A,MXI1,PCDH9,PDGFRA,ENPP2,SERPINE2,SERPINI1,RETREG1,ENOX1,RGS4,RPS6KA2,SH3GL3,FRMPD1,KDM4B,BEX1,ELOVL4,CEP68,RGL1,ACSBG1,SYT11,VAMP1,SYT1,COBL,TAL1,TGFBR3,TRH,SSBP2,DNAJC12,TRIM9,SLC17A7,GAN" Drug 4006_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.03E-12 2.46E-07 1.84E-09 2.09E-08 71 200 "NR0B1,BEGAIN,BIN1,SEMA7A,APBB2,APC,PPP4R4,CDK13,ADAM23,NRP2,BMP7,MAP7,CLDN10,CBFA2T2,CACNA2D2,CNTN1,ARMC8,IFFO1,CREM,ENTPD4,SEC14L5,SPOCK2,MFAP3L,EXOG,DTNA,HIPK3,SIDT2,TENM1,EPHB1,ZNF391,ZNF589,OGA,DKK3,GAP43,SIGLEC8,GRIK5,HPSE2,IL6ST,JAK2,MDM4,KITLG,MMP16,CNOT4,NPY,NLE1,PLCD1,SPATA6,C1orf54,BEND5,CARF,RTN1,ASAP3,FUZ,OGDHL,SNCA,SPTB,ATP11A,SEMA4A,MCF2L,ADGRL3,KLHL4,TEX15,CHST8,R3HDM1,CDK20,TRPC1,VGF,VIPR2,WNK1,PHTF2,AP3B2" Drug 3564_UP Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.12E-12 2.51E-07 1.86E-09 2.12E-08 70 196 "ASIC1,ARID1A,ADORA1,SEMA7A,KCNAB2,EPB41L5,CFLAR,CA4,CACNA1D,CACNA2D1,CACNG1,ARHGAP33,CLGN,FOXN3,CRMP1,OSBPL3,PLCH2,RIMS2,CDON,EDNRB,EFNB3,EGFR,MBNL2,TENM1,VPS26C,NRN1,ABCA8,CAMSAP1,AFF2,NSG1,GNG3,GPER1,GRM1,IL11RA,ITGA7,KCNB1,KHK,LMO1,ADAM22,MYO7A,NF1,NTRK2,OPRL1,PDE4B,EPN1,PRKAR1B,PRODH,PTPRN2,ZNF493,NUDT11,PNMA8A,SEMA6D,CPEB3,CNKSR2,SNCA,SPP1,ARHGAP26,CDK19,AJAP1,ARC,CUX2,CHST8,GPR161,NR2E1,RBFOX2,TRPC1,WIPF1,KLC2,NT5M,KCNAB1" Drug 3332_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.20E-12 2.55E-07 1.86E-09 2.12E-08 69 192 "ADRA1B,NME5,ALK,AMPH,AMT,MARK4,ST3GAL5,BAIAP3,CFAP410,CACNG1,CCKBR,USP2,CDH18,CHI3L2,TMEM59L,PICK1,CRYM,PDE4DIP,CNTNAP2,DOCK4,TMCC2,CDON,EDIL3,ST8SIA3,REEP2,PTK2B,TUBB4A,FGFR3,FHL1,C1orf61,DPYSL4,FYN,GAB1,GABRA2,CYP46A1,RND1,TDRKH,GRIK1,GRM2,TJAP1,ITGAM,KCND3,MPP2,OMG,PDE4A,SERPINI1,PIK3CD,PRPH,ZDHHC14,ZFHX4,RASA3,SH3GL3,ASAP3,PKNOX2,WDTC1,ZCCHC24,KIF21B,TSNAXIP1,RGL1,ACSBG1,SYT11,ABCC8,OBSL1,HEY1,FAM155A,DNAJC12,ZIC3,SLC17A7,EPM2A" Drug 3979_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.23E-12 2.56E-07 1.86E-09 2.12E-08 64 172 "DPF1,ADD3,ADRB2,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CDK5R2,CDH18,CLGN,STOML1,WHRN,AKAP12,CRYM,PDE4DIP,KIAA0513,ARMCX2,EFNB3,FAM13A,AASS,TUBB4A,FGFR1,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,STON1,KCNB1,KIF5C,VWA5A,MAP2,MPP2,NAP1L3,TMOD2,SERPINI1,PIK3CD,PRPH,RADX,GAL3ST4,NUDT11,SH3GL3,ASAP3,PKNOX2,ARHGEF40,TNIK,ZCCHC24,KIF21B,SOX15,NMNAT2,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,HEY1,RUNDC3B,DNAJC12,ZNF225,SLC30A3,SLC17A7" Drug 5441_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.28E-12 2.59E-07 1.86E-09 2.12E-08 65 176 "DPF1,ADD3,NME5,ST3GAL5,BAIAP3,CDK5R2,USP2,CDH18,CLGN,CRYM,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,TMCC2,SLC12A6,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,STX2,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,GLS,RAB40B,STON1,KIF5C,VWA5A,MXI1,NAP1L3,TMOD2,SERPINE2,SERPINI1,PIK3CD,MAPK10,PRPH,RAB3A,TTLL7,SMPD3,SH3GL3,WDR47,FAM214B,PKNOX2,TNIK,ZCCHC24,ARHGAP26,THSD1,RGL1,STXBP1,ACSBG1,SYT11,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 992_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 5.28E-12 2.59E-07 1.86E-09 2.12E-08 65 176 "ADD3,NME5,ARNTL,ST3GAL5,SCAPER,BAIAP3,CLGN,AKAP12,PDE4DIP,DOCK4,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,EDNRA,OPTN,EFNA3,EFNB3,STX2,DPYSL4,FYN,RND1,GLS,RAB40B,TDRKH,STON1,KIF5C,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,PIK3CD,PKIA,PRPH,RPS6KA2,SH3BGR,SH3GL3,PPM1E,SYBU,WDR47,FAM214B,SLC6A8,SLC22A4,ZCCHC24,KIF21B,TSPYL2,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TACC1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,DNAJC12,ZNF45,REEP1,NAV2,SLC17A7" Drug 5046_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.74E-12 3.30E-07 2.33E-09 2.65E-08 70 197 "ASPHD1,ACTN2,SEMA6A,AMPD3,KCNAB2,BMPR1B,CACNA1I,BTRC,HAP1,MTMR7,CD86,NEURL1,CACNA2D2,CHRNB2,STOML1,DNAJB5,RAB26,WHRN,COL9A2,SPOCK2,EDNRA,EDNRB,CNNM1,SIDT2,COQ7,LRRC17,NCALD,SPEG,PTK2B,FGF1,HPCAL4,PRELID3A,SYT17,GLYR1,GPR22,GRIK5,GRM1,NXPH3,ICA1,KCNN1,KIF5C,MARK1,MATN3,MOBP,MX1,P2RY13,NPTX1,PDE3B,PIK3CD,PPARA,LRRN3,PRKAR1B,PRPH,RGS12,FBXW7,TCP11L1,SH3BP2,ASAP3,SLC15A2,SYT11,PLCB1,SYT5,SMG6,DOCK9,HIF3A,CHST8,TNS1,REEP1,PARP6,HRASLS" Drug 5563_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-12 3.30E-07 2.33E-09 2.65E-08 70 197 "ADD2,C1QTNF1,FAM135A,TRMT9B,BIN1,DNAH17,BRINP2,ATP2A2,CACNA1I,LDLRAD4,HAP1,CACNA2D2,EPS15L1,MYRIP,CNTNAP2,PHYHIP,KBTBD11,DRD1,ATN1,EDNRA,DMTN,EFS,CEND1,ST3GAL6,FGF1,FGFR3,GABRA2,GABRA5,GLYR1,GLS,ATF7,NR3C1,GRM8,KIT,KPNA5,AFDN,TAGLN3,LYRM9,MYO7A,NF1,NNAT,NTRK2,NTRK3,PDE1C,CAMKV,NLE1,LRP12,PTH1R,ZNF493,ZMAT4,SEMA6D,SELL,CPEB3,ST8SIA1,SLC11A1,SNAP25,SNCA,ZNF415,HECW1,ZNF423,CDK19,SPART,ATP10B,SAMSN1,POPDC3,TCF7,TRPM2,UBE3A,VIPR2,WIPF1" Drug 3875_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-12 3.30E-07 2.33E-09 2.65E-08 70 197 "ABHD6,NDRG2,ADCY2,ADORA2A,TRMT9B,BIN1,CNTNAP1,PRX,ATM,NRP2,CACNA1I,CACNA1D,CAMK2B,CDH10,CDH18,RCBTB2,TAOK2,SULT4A1,LY86,CNTFR,NOS1AP,DAPK1,SPOCK2,ETV1,GAB1,GAD2,DISC1,ALDH1L1,ADAM28,GLYR1,MSL3,ADAMTS13,KLF12,HLF,AFDN,ADAM22,BCO1,NCF2,NF1,NNAT,CNOT4,OMG,CLDN11,CDK14,SERPINI1,PLTP,STRN3,MINDY2,ELOVL2,RGS10,KCNIP1,CLIP1,CSRNP3,SH3GL3,BCAN,KDM4B,SOX2,TNIK,SPP1,CDK19,POGZ,MAPK8IP3,ATP11A,TBL1X,DMXL2,DOCK9,DNAH7,ZNF45,KCNAB1,SSPN" Drug CID000013296 4-ethylsulfonylnaphthalene-1-sulfonamide Stitch 6.87E-12 3.37E-07 2.35E-09 2.68E-08 51 123 "KIDINS220,ASCL1,CHRD,HCN2,BSN,CALB1,CALB2,RGN,NOG,CNTFR,AKAP5,CRMP1,MED24,PARD6A,TRAPPC9,EDN1,EDN3,EDNRA,EDNRB,ELAVL3,ENO2,FOXO3,DPYSL4,B3GAT1,GFAP,GFRA1,GFRA2,GNAS,GRM7,GRM8,ACOT7,IL11RA,LIFR,SMAD1,NOS1,NPY,HCN1,NTRK2,NTRK3,PRPH,RET,SCN2A,SLC15A2,SOX10,SST,SYP,TNFRSF1B,TNS1,TRPC1,UCHL1,SLC17A6" Drug 7453_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.07E-12 3.46E-07 2.39E-09 2.72E-08 66 181 "ADD3,NME5,ALAD,MARK4,BMP7,ST3GAL5,RAB29,CLGN,WHRN,AKAP12,KIAA0513,RIMS3,ARMCX2,DNAJC6,EFNA3,EFNB3,MRNIP,STX2,TUBB4A,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RAB40B,STON1,INPP5B,KIF5C,MAP4,MPP2,MXI1,NAP1L3,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,PLCD1,PKIA,GRAMD1C,PRPH,PTAFR,RAB3A,RPS6KA2,SH3BGR,SH3GL3,WDR47,FAM214B,ZCCHC24,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TACC1,KIAA0930,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7" Drug 4954_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.07E-12 3.47E-07 2.39E-09 2.72E-08 65 177 "ADD3,NME5,APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,SRGAP3,TMCC2,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,STX2,DPYSL4,FYN,CYP46A1,RND1,RAB40B,STON1,KIF5C,MAP2,MXI1,NAP1L3,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PRPH,PTCH1,TTLL7,RPS6KA2,SH3GL3,WDR47,PKNOX2,ARHGEF40,ZCCHC24,ZBTB43,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,TGFBR3,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C,PLSCR4" Drug CID000005202 serotonin Stitch 7.46E-12 3.66E-07 2.50E-09 2.85E-08 149 554 "ACHE,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,AMT,APAF1,APOC2,API5,APP,PDXK,ATM,ATP1A1,ATP1A2,ATP1A3,ATP1B3,MPDZ,CACNA1I,CACNA2D1,CACNB4,CALB1,CALB2,CAPN3,CCK,CHGA,CHGB,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,CNR1,SLC32A1,PLCXD3,SLC29A4,DRD1,EDN1,GPR61,EN2,ENO2,DMTN,STX2,SIRPB1,RPS6KC1,ZMYND10,PRMT5,PPP1R1B,ACTL6B,B3GAT1,GABRA1,GABRA4,GABRB3,GAD1,GAD2,GALR1,INPP5K,GFAP,CBX1,LOXL3,PLCD4,GRIK1,GRIN1,NR3C1,GRM2,GRM3,CIT,HPS5,HRH3,HLF,HP,HPR,HTR2A,HTR5A,IGF1,KCNA6,GPR62,KCNH2,KCNJ3,KCNJ5,MAOB,NDP,NPY,NUCB1,NUCB2,OPRL1,P2RY1,PAH,PDPK1,PDYN,PENK,PLCB2,PLCD1,POLR2F,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,QDPR,RAB3A,FEZF2,SLC6A15,RGS7,GLDN,RPS6KA2,S100B,MAPK12,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,EFHD1,RIMS1,SNAP25,SOX10,NPAS3,SST,ADHFE1,STX1A,JMJD6,SUPT5H,PLCB1,SYP,SYT1,TAC1,TAC3,TACR1,TF,GPR161,ACTR6,PRMT8,TRH,P2RY12,PORCN,SLC17A7,PLD4,SLC17A6" Drug 4071_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.83E-12 4.33E-07 2.87E-09 3.26E-08 70 198 "SYN3,ADCY6,NR0B1,PLA2G6,DOC2A,APC,CDC14B,PRX,DDX3Y,SLC2A11,BCHE,RGS11,BMP7,SCAPER,GYG2,CDK5R2,CAMK2B,ARHGEF2,NRXN3,VAX2,NRG2,CSF1R,LRIG1,RIMS2,SEC14L5,DMPK,TRAPPC9,DTNA,SEMA3D,NCALD,FABP7,CAMSAP1,AGAP2,PRELID3A,DKK3,DISC1,PCDH17,POLL,TPPP,CACFD1,GSTM5,ADAM22,NF1,NTRK2,PLCD1,PTCH1,PTN,PTPRD,GAL3ST4,RNASE1,PBRM1,GSTCD,TMEM206,SLA,PKNOX2,ZNF334,SLC20A2,SLCO1A2,ARHGAP26,SPTB,RBM26,ARC,SYT5,MCF2L,TF,GPR161,TNS1,CHST5,NSD2,JPH3" Drug 5076_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.83E-12 4.33E-07 2.87E-09 3.26E-08 70 198 "ASPHD1,ASIC1,ACTN2,AMPD3,AMT,SEMA7A,APOC1,SEMA4G,MARK4,ADAM23,ADGRB2,MTMR3,CACNA1I,CACNA1G,CACNA1A,CAPN3,RUNX1T1,SLC16A4,CDH10,KIAA1549L,CLCN4,WHRN,AKAP5,SH2B1,HAPLN1,VCAN,RIMS2,FAM131B,TOX,HEPH,ST8SIA3,EIF4G2,COQ7,MTSS1L,KAT8,FAM49B,PCDH17,CSDC2,CACFD1,GRM7,KCNA4,MAN2A2,MATN3,ADAM22,NF1,NOVA1,PPARA,LRRN3,MAPK10,WDR25,PTH1R,PTPRB,PID1,RGS7,DOCK10,SLA,PKNOX2,SLC11A1,OGDHL,ZHX3,DDN,SPART,ATP10B,PHLDB1,KIAA1107,AP4E1,SLC44A1,CHST5,SEMA3B,KCNAB1" Drug 3583_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-12 4.33E-07 2.87E-09 3.26E-08 70 198 "SYN3,ADORA1,SEMA6A,BIN1,SEMA7A,KCNAB2,CACNA1I,BAIAP3,CACNG1,CAMK2B,CBFA2T2,CDH10,CHRNA4,TAOK2,HOMER3,FAM149A,SNCAIP,PDE4DIP,HDAC9,SPOCK2,CTIF,SV2A,DRD1,EFNA3,AASS,EIF4G2,ELAVL3,ABCA8,FGFR3,B3GAT1,DISC1,GLI2,GPM6A,LPAR4,ITPKA,KCNJ4,VWA5A,SMAD1,MGAT3,SAMD14,NF1,DDR2,OPCML,TREM2,PDE1C,EPN1,PDZRN4,PMP2,POU3F2,SNRK,PTCH1,PTN,ZSCAN2,RGS3,RGS12,RPS6KA2,SCN2B,ASIC4,ZNF821,RPH3A,PKNOX2,SNCA,PEG10,CLSTN2,OBSL1,HEY2,TRPM2,TUBB1,BEST1,GDPD5" Drug 3371_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-12 4.33E-07 2.87E-09 3.26E-08 70 198 "RALGAPA1,SYN3,ASIC1,TKTL1,ADORA3,PLA2G6,LTBP4,MRTFA,APAF1,GYG2,BAIAP3,CACNG1,CAMK2B,CDH2,SULT4A1,AKAP6,PLCH2,CTIF,SRGAP3,EDNRB,IGSF6,APC2,PIPOX,F5,FOXG1,FLNC,SORBS1,ERAP1,NEU3,LYVE1,GNAO1,GPM6A,ATF7,GPER1,NR3C1,TJAP1,IL6ST,ITIH2,ITPKB,KCNB1,KCND3,KIF5A,TAGLN3,MX1,PENK,PIK3CD,CEP41,PROX1,SAMD9,WDR25,PTAFR,PTPRB,SLC6A15,SH3GL3,SLCO1A2,SLN,SORCS3,FAIM2,KDM4B,SOX10,HECW1,SPP1,PEG10,MAPK8IP3,KIAA1107,HEY1,HEY2,SLC30A3,SLC17A7,KCNAB1" Drug 4428_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.83E-12 4.33E-07 2.87E-09 3.26E-08 70 198 "ACTN2,NDRG2,BEGAIN,PDE8B,ATP2B2,KIF1A,CDK5R2,LDLRAD4,CACNA1A,CAMK2A,CAMK2B,NEURL1,SEPT7,CHRNB2,RAB33A,SUSD5,PDE4DIP,CTNND2,EDRF1,SNPH,CDON,EDN3,RASGRP2,FABP7,CORO2B,DLC1,PDLIM5,DISC1,SRCAP,LYVE1,RND1,GLI2,GRIK2,CACFD1,ADAMTS8,HPSE2,ICA1,IRF8,IL6R,LAMA2,NELL2,NF1,EPN1,POU6F1,PPP5C,CEP41,MAPK7,MAPK8,PTPRN2,ACSS3,SUSD4,RASGRF1,RGS10,RGS12,HKDC1,CNKSR2,CXXC4,PDZRN3,SOX10,ZNF423,TACR1,MCF2L,KLHL4,OBSL1,SLC44A1,BHLHB9,TRO,ZMYND8,VAV2,WNK1" Drug 4125_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.03E-12 4.43E-07 2.89E-09 3.29E-08 69 194 "ASPHD1,NDRG2,ADD2,ALCAM,AMPD3,ANK1,GAS7,CDC14B,PPP4R4,CACNA1I,CD86,CDO1,CLCN4,SULT4A1,ARHGEF6,CRY2,SNCAIP,MICAL2,DAPK3,SPOCK2,DCC,ARMCX2,PLXNC1,OLIG2,LRRC17,PTK2B,FGFR3,SIGLEC8,GFAP,ATXN2L,ICA1,KCNJ5,KCNMA1,KCNN1,SMAD1,MAP2,MAPT,AFDN,MN1,MOBP,CD200,ADAM22,MX1,NEFM,NNAT,NOVA1,OMG,OPCML,GPR85,CEP41,PRKAR1B,ZSCAN2,RAB3IL1,RGS10,SALL1,SH3BP2,LIMCH1,KIF13A,ATP10B,VAMP1,TAC3,KIAA1107,TMOD1,TRPC1,FLRT1,WNT7A,SLC17A7,HRASLS,SSPN" Drug 4082_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.03E-12 4.43E-07 2.89E-09 3.29E-08 69 194 "DPF1,ACTN2,ADORA1,PLA2G6,C1QTNF3,LTBP4,SEMA7A,PKP4,ADGRB2,SCAPER,CA12,CAMK2B,RUNX1T1,SCARB1,RAB33A,CLCN4,SLC24A2,STOML1,CNTN1,FAM149A,IFFO1,ARHGEF4,DAPK1,JAKMIP2,RABGAP1L,SHANK1,SEMA3D,NCALD,PTK2B,FGFR1,PRELID3A,DISC1,ATP8A2,ADAM28,PCDH17,GNAL,GPR22,GRM3,ATXN2L,KLF12,IGF1,SCIN,KCNH2,KITLG,MOBP,CD200,NF1,PCBP3,PBX1,PCDH9,PDE3B,CEP41,ELOVL2,CRTAC1,RET,RGS12,GSTCD,KCNIP1,ZNF334,SLC14A1,SLCO1A2,KIF13A,TNIK,SPTB,MCF2L2,DMXL2,TNS1,CADM1,DPF3" Drug 6932_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.40E-12 4.61E-07 2.99E-09 3.40E-08 66 182 "ASPHD1,ABHD6,ADD3,ARNTL,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,STOML1,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,TUBB4A,BAIAP2,DPYSL4,PDLIM5,FYN,CYP46A1,GLS,RAB40B,STON1,KIF3A,ACOT7,HSF2,KIF5C,MEIS1,MPP2,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,RETREG1,PMP22,PKIA,PRPH,RAB3A,RGS10,SH3BGR,SH3GL3,WDR47,SLC6A8,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,GDPD5,NAV2,SLC17A7" Drug 5065_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 9.44E-12 4.63E-07 2.99E-09 3.40E-08 65 178 "ADRB2,MTUS1,APAF1,SHROOM2,CDC14B,ARNTL,MARK4,NRP2,ST3GAL5,HIP1R,USP2,WHRN,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,PLPPR4,SRGAP3,SIDT2,RGS17,PTK2B,TAOK3,TESK2,BAIAP2,DPYSL4,FYN,RND1,GLS,STON1,TPPP,DIPK1A,ITGA7,KCNB1,KCNH2,KIF5C,LIFR,MAP2,MAPT,MMP16,ADAM22,NTRK2,PCDH9,PDGFRA,PDPK1,SERPINI1,RETREG1,PRPH,PTCH1,PID1,ENOX1,RGS4,FBXW7,SH3GL3,ASAP3,KDM4B,DOP1A,TNIK,ARHGAP26,ELOVL4,RGL1,SYT1,COBL,DNAJC12,SLC17A7" Drug ctd:D015124 8-Bromo Cyclic Adenosine Monophosphate CTD 9.73E-12 4.77E-07 3.06E-09 3.48E-08 177 693 "AGT,ADGRF5,ABCD2,OGT,MYH7B,APAF1,APC,N4BP2L1,DOCK11,CFLAR,CABP7,CARS,RUNX1T1,AIFM1,SCARB1,ARHGEF2,REPS2,CLGN,ADGRG1,CHN1,NGEF,FAM19A5,SULT4A1,CNR1,AKAP7,WHRN,NECTIN3,CRHBP,ABCG1,PHACTR3,ARHGEF4,RIPOR2,DGKB,SPOCK2,BRINP1,ARMCX4,PITPNC1,CNIH3,LYPD1,RHOBTB1,CCDC3,GRIN3A,CALN1,NR1D2,CDON,KLHL5,EGFR,HSD17B14,LRRC17,STX2,ETV1,ST3GAL6,FDFT1,FGF13,FOXO3,TACC2,DACH2,ABLIM2,GABRA4,GABRG1,GALR1,NEK6,IQGAP2,GAP43,ERAP1,DNER,GCK,GFAP,KIRREL3,GK,STARD3,INSM2,GPR22,GPR37,GRB10,GRIA1,ADAMTS8,NR3C1,LINGO1,ADAMTS6,WIF1,HAS2,PTGDR2,HLF,SCRG1,HNF4G,HPCA,HSD17B1,HSP90AA1,IGF1,IGFBP1,ITPKB,KCNC2,KCND2,KIF5C,KLRC2,KLRC3,LSS,MAPT,SYT9,MIA2,MMP16,SESN3,CCDC80,NAP1L2,NCF2,NPPA,NRCAM,OMG,PCSK1,PDE1A,PDE2A,PDE3A,GNG2,PENK,SERPINI1,SMOX,PSAT1,PPARA,MAPK3,MAPK10,PTHLH,PTK2,PTPRE,PTPRZ1,PID1,ENOX1,SLC25A36,ROBO2,RORB,LGR4,RXRG,RYR3,TNFRSF19,MRAS,NLGN4Y,SGK1,SLC6A9,LIMCH1,SNCA,PDZRN3,SOX5,DOK5,SPP1,UNC5B,PEG10,LMO3,SMOC1,NUDT10,PLCB1,TAC1,MCF2L,CUX2,TRIM2,SYNE1,PCDHB4,SIRT1,CDH22,THRA,HEY2,TMOD1,TPM1,ANKRD20A2,CADM1,FAM155A,OSBP2,VGF,VLDLR,LAT2,ETNPPL,SF1,PCDH20,PMEPA1,CADM2,SCG2,NAV3,MSRB3" Drug CID000005413 tetraethylammonium Stitch 1.02E-11 4.99E-07 3.18E-09 3.62E-08 79 236 "ASIC1,ACHE,PHF12,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CACNA1D,CACNA2D1,CACNB2,INA,LRBA,ASIC3,CHRM1,SLC22A6,NRXN2,CPS1,DMPK,SLC29A4,EDN1,SGK2,KCNMB2,ABCA8,PTK2B,TPK1,KCNMB4,GUCY1A2,GUCY1B1,HRH3,IGF1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MTR,MYBPC1,NOS1,NPR2,KCNK10,ABCB1,PKD1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,SCN4B,SLC15A2,SLC22A4,SCN3B,NCDN,TAC1,SLC19A3,SGK3,UBTF,KCNAB1" Drug 4098_UP Furazolidone [67-45-8]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-11 5.81E-07 3.63E-09 4.13E-08 69 195 "AGT,NR0B1,BBOX1,BEGAIN,APC,GAS7,ASCL1,ATP1A2,ATP2B3,N4BP2L1,ADGRB1,FGF17,BAIAP3,CAMK2B,SLC16A4,CDH10,ARHGAP33,NRXN3,CSF1,CTNND2,NOS1AP,PHYHIP,C2CD2L,DYRK1A,HEYL,SRPK3,RASGRP2,ANKMY1,FAM198B,ATP8A2,GRIN1,GUCY1A2,HNMT,HPCA,HTR5A,KCNJ10,MAN2A2,MAPT,MMP16,MYO7A,NPTX1,NTRK3,PALM,PBX1,ST8SIA5,PPP1R1A,MARCH1,CCDC40,KHDRBS2,RNASE1,SCN2B,NTNG1,RPH3A,PKNOX2,RIMS1,SOX2,HECW1,RBM26,TACR1,KLHL4,HIF3A,TF,SPX,THRA,CHST5,TRPC3,CADM1,UBE3A,FAM13C" Drug 6507_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-11 5.81E-07 3.63E-09 4.13E-08 69 195 "ASIC1,AGT,AK2,PLA2G6,PPP4R4,MARK4,SLC4A4,KSR1,LDLRAD4,CFAP410,CA4,USP2,ARHGEF1,SCARB1,PLEKHB1,LHX2,DNAJB5,HOMER3,CABP1,CYBB,CTIF,KBTBD11,RCAN1,DTNA,PLXNC1,TENM1,VPS26C,DLC1,DCTN2,PCDH17,RUNDC3A,GNAL,GPER1,GRM8,GSTM5,KCNMA1,KIF5A,MATK,MBD1,ADAM22,RETREG1,PLCD1,NECAB2,POU3F2,LRRN3,PPP5C,GON4L,WDR25,ELOVL2,RGS3,SBF1,PPP1R9A,PREX2,ARHGEF40,SNCA,BEX1,DDN,ST5,MAPK8IP3,ARC,ADGRL3,IQCE,TRIM2,DOCK9,PCDHA5,TNS1,SLC13A3,XRCC4,ADAMTS9" Drug 6065_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-11 5.81E-07 3.63E-09 4.13E-08 69 195 "LTBP4,MRTFA,APLP1,PRX,ARHGDIG,PLA2G4C,RGS11,BAIAP3,CDH2,CDO1,CLCN4,CSF1,PHF14,RIPOR2,ATN1,CAMSAP1,FOLR2,PDLIM5,GPR153,ATP8A2,ALDH1L1,SRCAP,C1QL1,RAB30,ADAMTS13,GRIK5,NR3C1,GRM7,ATXN2L,HPSE2,C2orf72,KCNB1,KIFC3,MATK,MEF2C,MMP16,MYO7A,ZNF862,P2RY1,SNTG1,CDK18,PDE4D,PACSIN1,TNPO2,PPP5C,MAPK8,VPS13C,PTAFR,ZNF493,RASGRF1,TRIM68,RGS12,RPS6KA2,SATB1,SLC2A5,PKNOX2,LIMCH1,RIMS1,TNIK,SPTAN1,SPTB,SPART,EPB41L3,INKA2,HEY2,R3HDM1,VIPR2,LAT2,SSPN" Drug 3791_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.26E-11 6.17E-07 3.82E-09 4.34E-08 63 171 "ABAT,ABHD6,MTUS1,APAF1,CDC14B,ARNTL,ADGRB2,ST3GAL5,CDK5R2,SYNGR3,NRXN3,ABCG1,PDE4DIP,CTH,PLPPR4,EFNA3,RGS17,TUBB4A,TAOK3,BAIAP2,DPYSL4,SORBS1,PNMA2,FYN,PCDH17,RND1,STON1,TPPP,GUCY1B1,KCNH2,KIF5C,LIFR,MAPT,KITLG,MMP16,MMP17,TAGLN3,FXYD7,NPTX2,PCDH9,PDE2A,PDGFRA,ENPP2,SERPINI1,FXYD1,SYTL2,ENOX1,RGS4,FBXW7,ASAP3,SNCB,TNIK,THSD1,ELOVL4,RGL1,SYT11,SYT1,COBL,OBSL1,SSBP2,DNAJC12,TRIM9,SLC30A3" Drug 2835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.26E-11 6.18E-07 3.82E-09 4.34E-08 64 175 "DPF1,ADD3,NME5,ALCAM,ST3GAL5,SPAG9,CLGN,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TMCC2,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,RASGRP2,TUBB4A,DPYSL4,FYN,CYP46A1,RND1,TDRKH,STON1,KIF3A,MITF,MPP2,NAP1L3,PCDH9,TMOD2,SERPINE2,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,LRRC49,SH3BGR,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,ZCCHC24,KIF21B,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,ZEB1,TRIM2,TGFBR3,HEY1,RUNDC3B,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug ctd:C044887 beta-methylcholine CTD 1.35E-11 6.62E-07 4.06E-09 4.62E-08 360 1657 "ABCF1,ABR,ACADM,ASIC1,GPRIN1,NDRG3,ADAR,ADCY6,GALNT13,ADD3,CDC7,SORCS1,UNC5A,RNF150,AP1B1,INTS2,MTUS1,OSBPL1A,TBC1D14,SEMA6A,SPOP,KCNT1,GPRASP2,BEGAIN,AMH,LRCH2,PKP4,APAF1,UPRT,GPAM,FAM131A,MIER1,ASCL1,DACT3,NUMB,RASL11B,DYNLL1,ATM,ATP1A1,ATP1B3,NOL4,ATP6V0A1,KIF1A,BBS2,ARHGEF7,CASTOR3,MTMR3,NIPA1,BSN,CAMK2G,KRIT1,DCLK1,DIS3L,CHGA,CHGB,CHM,SLIT2,IQCK,IFFO1,TBPL1,SMARCAL1,NSL1,PREPL,RNF14,HINFP,CSF2RA,FEZ1,ARHGEF10,CSNK1G3,RIMS4,CNTNAP2,PHF14,NRSN1,GPSM1,MYADM,CENPL,MATR3,RIMS3,INTS1,IP6K1,DBT,ARMCX2,TIAM2,HP1BP3,PARD6A,SV2A,SGSM2,ARNT2,KBTBD11,DLG4,GNE,DNAJB6,ABCC5,DNM1L,SEZ6L2,ANKRD46,RBM12,EFNB3,CELSR3,PHF20L1,SUGP2,MBNL2,KMT5B,ASB3,EIF4G1,EIF4G2,COPS4,TNK2,EIF1,LRRC17,GPHN,RABEPK,NCALD,MRPL10,CEND1,EXTL2,GMPR2,FKTN,STRADA,PRMT5,CAMSAP1,HPCAL4,CAP2,IP6K2,SYNCRIP,FOXO3,SEMA4D,ANKFY1,DPYSL4,ZCCHC17,TACC2,POMT1,USP21,NPTN,ARFGAP2,NSG1,MPP6,OGA,FYN,PHYHIPL,BRPF3,FAM120B,ZNF234,ZNF274,MTHFD2,ZNF559,GART,WASF3,GPR162,GFRA2,RUNDC3A,MSL3,CBX1,INSM2,PSRC1,RAPGEF1,PLPP7,GRIN1,BTN2A1,RNF165,GUCY1A1,GYG1,CELF3,MAN1B1,AGBL5,HNRNPK,HSP90AA1,ICA1,LRRCC1,PLD5,IL11RA,KCNMA1,KCNQ2,GATD1,KIF2A,MAP2,MAPT,LYPLAL1,MARK3,MEIS2,KCTD6,MRPL42,MYCN,MYT1,NAP1L1,NBL1,NCAM1,NELL1,NEK1,NFE2L2,CNOT4,SLC11A2,NRCAM,NRDC,DDR2,NUMA1,OPRL1,ETFRF1,PCMT1,PDCD2,PDPK1,SLC10A4,CYTL1,PFKFB3,PFKFB4,PFKP,NOMO2,ANLN,ZFYVE21,XRN1,PCDH18,PLXNB1,STRN3,ING3,FSD1,PPM1B,PPP2R2C,LRRN3,CRLS1,PPP3CB,PPP3CC,CEP41,PKIA,PRKCZ,MAPK3,SLC26A11,PROX1,APTX,GON4L,SPDL1,EML5,PEX5,RIPOR1,TTC13,PPP2R3C,ATG16L1,RAP1GDS1,RBBP6,RBBP8,RDX,RGS4,RGS12,RPRD1A,CCDC25,RORB,ELP2,RPE,TMEM100,RTN1,RMI1,FOXRED2,SBF1,SCN2A,TNFRSF19,TRIM46,SUPT20H,PUF60,ITSN1,FUZ,PAAF1,CLSTN1,URGCP,NBPF1,EPN2,DHX30,SLC6A8,BTBD7,ARFGAP1,MAST1,CDK5RAP2,SNAP25,SNCA,USP33,SON,SOX11,SP2,NMNAT2,TEX2,RAP1GAP2,LMO3,TROVE2,ZNF302,LARP4,MAPK8IP3,PHLDB1,SULF2,NSFL1C,KLHL7,SYT11,SUPT5H,SYNE2,VAMP1,SYT4,POPDC3,PJA1,CAMTA1,EXOC7,EHBP1,ZFP90,TRIM2,TCF12,SLC35G2,SIRT1,ZNF106,SLC44A1,FBXL16,HEY1,ACTR6,TMOD1,KCTD2,TP53BP2,TPD52L2,CDK20,TPM3,TPM4,SYNPO2,METTL3,TRIO,TRO,FNDC5,SSBP2,TUB,UBC,EIF4ENIF1,UBE2H,SLC35A4,UBTF,DNAJC12,USP1,CCDC136,CCDC14,VSNL1,CLIP2,CLDND1,XPO1,SF1,ZNF32,NDRG4,ZNF142,POLR3H,FSTL5,ZNF189,SPIRE1,PLPPR5,TFIP11,PMEPA1,STOX2,PRDM8,LMAN2L,TUBA1A,CIAPIN1,ITM2C,PCBP4,MVB12B,ST7,JMJD1C,ZNF248,FXR1,ST8SIA2,JPH3" Drug 3833_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.51E-11 7.38E-07 4.50E-09 5.12E-08 70 200 "NDRG2,ADCY2,APBB2,RGS20,ASPH,BRINP2,ATP2B2,RGS11,GYG2,CACNA1I,BAIAP3,USP2,SLC16A4,CBFA2T2,CDO1,CLGN,CHRNB2,FADS2,QKI,SNCAIP,CSF1,PHF14,RASSF2,TMCC2,DYRK1A,EFNB3,ELAVL3,EN2,ERCC2,CEND1,FGF13,FGFR1,CAMSAP1,AGAP2,PDLIM5,CAMKK2,SRCAP,RUNDC3A,ATF7,PTGDR2,IRF8,TJAP1,ITIH2,JAK2,KCNJ5,VWA5A,MMP16,ADAM22,NEUROD1,NF1,PDE3B,TMOD2,PTHLH,NKAIN1,PID1,ZNF493,KCNIP1,SELL,PPP1R9A,CPEB3,FBXO11,SLC2A5,SLC11A1,RBM34,HECW1,ZC3H13,ARC,SZT2,SPHK2,EMSY" Drug 413_UP trichostatin A; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 1.55E-11 7.60E-07 4.60E-09 5.24E-08 69 196 "ADD3,APOC1,ARNTL,ARRB1,PLA2G4C,ALDH4A1,ATP1A2,BMP7,MTMR3,RAB29,BTRC,CAMK2A,CLTB,IFFO1,ARHGEF4,DTNB,ABCC9,OPTN,EFNB3,MBNL2,ENO2,OLFM1,FHL1,DPYSL4,FYN,CYP46A1,USP19,GLS,RAB40B,ATF7,GRIA4,GRIN1,BTN2A1,RNFT2,HMX1,KIF5C,MITF,FXYD6,DDR2,OPCML,PDE4A,SERPINI1,MAPK8,PRPH,PTCH1,RAB3A,GAL3ST4,RGS3,TMEM206,ATXN1,PPM1E,SLC1A2,ZNF365,SLC9A5,SMARCD3,DOP1A,TNIK,ZCCHC24,ZSWIM8,ZNF423,ACSBG1,TRIM2,TF,CDH22,AMOT,DNAJC12,WIPF1,CLIP2,ZNF184" Drug ctd:D014638 Vanadates CTD 1.64E-11 8.02E-07 4.83E-09 5.50E-08 294 1303 "CPNE2,NCKAP5,KDM5D,ZNF608,OSBPL6,SRPX,ARHGAP20,PCDH10,FAM135A,ALK,GPRASP2,SEMA7A,CNIH2,APBA2,APBB2,NT5C3B,CACHD1,PPP4R4,CASK,STK33,ZBTB10,DDX3Y,SLC4A4,RNF182,ADGRB2,BBS2,NRP2,CDK5R1,ST3GAL5,JAZF1,GYG2,C5,NIPA1,GPC2,CA4,CA12,CAMK2B,CAMK2D,VXN,CAST,KYAT1,LDB2,CDH10,CDH18,CIART,ADGRG1,CHN1,ABCG2,COL4A5,ABI3BP,ZNF385A,LRIG1,FEZ1,SUSD5,SIPA1L1,CTNND1,PYGO1,DOCK4,HDAC9,GAPVD1,TOX,RASSF2,PLEKHM1,MYEF2,MED24,NTM,CCDC3,ARNT2,CDON,CPEB2,DPYSL2,RCAN1,MAMLD1,E2F5,EDIL3,TSPAN5,ATL1,CNNM1,RASGRP1,FAM13A,AASS,EPB41,SLC43A2,EPS8,CEP85L,ETV1,EYA1,EZH1,NSRP1,TAOK3,SCML2,CORO2B,CHST15,FKTN,MED12L,PRKAG2,SEMA4D,FLT1,POMT1,SMC2,PDLIM5,GABRA3,ERAP1,DNER,GCK,GLDC,GLUL,STARD3,KIAA1958,MAP7D2,KCNMB4,GNAL,GNG4,GPT2,GPD1,TDRKH,CNTRL,PARD3B,KIF3A,IRAK3,TOX2,KLF12,BACH2,HLF,NEGR1,ZNF678,KCNK2,KCNMA1,KHK,KIF5C,KIFC3,KIT,L1CAM,STMN1,MARK1,MEIS1,KITLG,MID1,MMP16,CD200,MSR1,NCAM1,NCAM2,ZC3H12B,NCF2,NFIA,NME4,NOVA1,NPR2,OLR1,OPHN1,GPR137C,ZNF827,PAX6,PBX1,PRTG,PDE1C,ENPP2,PDPK1,GNG2,TMOD2,PFKFB3,FAM98B,ABCB1,SERPINE2,PIK3R1,SNX10,XRN1,NLE1,FTO,PLP1,PLTP,PSAT1,MED1,PRKAB2,PKIA,PRKCZ,MAPK3,SYTL2,LAMA1,ELOVL2,PTK2,EML5,PTPRE,PTPRG,RIPOR1,ZNF844,PID1,RAD17,SH3TC2,ZNF493,OXR1,RASGRF1,FIGN,RGS4,TTLL7,KLHL11,LGI2,RAVER2,ZNF671,RPS6KA2,LGR4,MEG3,RTKN,STX1B,CCDC112,TMEM156,RMI1,ATXN1,CASC3,GALNT10,ASRGL1,PPP1R9A,PPM1E,FERMT1,CHD9,CCDC92,ANKRD6,ABLIM3,ZNF365,SLC2A5,EPN2,FAM214B,ZNF430,SLC8A1,SLC12A4,GKAP1,CDK5RAP2,SMARCE1,SNAP25,SNCA,KIF13A,TNIK,MCF2L2,NFASC,STOX1,THSD1,SSTR1,ZC4H2,RGL1,FGD4,VPS13A,SLC37A2,DNMBP,KIAA1107,ANO4,TCF4,SATB2,ZFP90,PCDHB15,PSD3,TF,TGFBR3,ZNF34,FBXL16,TK2,ERCC6L2,FAM124A,PIK3R5,TPD52,TUBA3FP,TRPC3,TSC1,TST,TUB,DNAJC12,SLAIN1,VLDLR,LMF1,PORCN,XRCC4,ZNF708,FMN2,PLPP4,ZNF138,SYNC,PMEPA1,STOX2,TUBA1A,SEMA3B,NAV3,URM1,CAB39L,PCBP4,MVB12B,PLSCR4,RGS7BP,FZD3,CAMK1G,RSPRY1,SSPN,NETO2,DPF3,GAN" Drug 2247_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.67E-11 8.17E-07 4.90E-09 5.57E-08 65 180 "DPF1,ABHD6,ADD3,NME5,MARK4,ST3GAL5,BAIAP3,CDH18,CLGN,WHRN,PDE4DIP,DOCK4,KIAA0513,ARMCX2,DNAJC6,TSPAN5,EFNA3,EFNB3,FAM13A,RASGRP2,TUBB4A,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,RAB40B,STON1,RNFT2,SYNPO,NAP1L3,PCDH9,TMOD2,SERPINI1,PIK3CD,PLCD1,GRAMD1C,PRPH,PTAFR,PTCH1,SATB1,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,RUNDC3B,TRPM2,SSBP2,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 5217_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.68E-11 8.25E-07 4.91E-09 5.59E-08 63 172 "ADD3,NME5,ST3GAL5,BAIAP3,USP2,SLC16A4,CDH18,CLGN,CRY2,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TMCC2,OPTN,EFNA3,EFNB3,MBNL2,TUBB4A,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,KCNN2,KIF5C,VWA5A,MAP2,MXI1,NAP1L3,NEK1,PCDH9,SERPINI1,PIK3CD,GRAMD1C,PRPH,GAL3ST4,SH3GL3,ASAP3,WDR47,FAM214B,PKNOX2,TNIK,ZCCHC24,KIF21B,SPTAN1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug CID000003559 haloperidol Stitch 1.75E-11 8.57E-07 5.07E-09 5.77E-08 114 394 "ABAT,ADCY2,ADCY5,SLITRK1,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,AGT,OSBPL8,KCNAB2,CACNA1A,CACNA1B,CACNA1E,CALM1,CBR1,CCK,KCNAB3,CHRM1,CNR1,COL11A2,DYNC1I1,DRD1,DTNA,RASL12,HSPA12B,ZMYND10,PPP1R1B,BAIAP2,FOXG1,FOXM1,TRIM16,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GAP43,DISC1,NTNG2,TCERG1,LOXL3,MCHR1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PACSIN2,HTR2A,HTR5A,KCNA1,KCNA2,KCNA4,KCNH1,KCNH2,MAOB,KITLG,NOS1,NPY,NPPA,OPRL1,PAH,PDE4B,PDE1B,PDPK1,PDYN,PENK,ABCB1,PACSIN1,PTPA,PPP3CC,PKN2,PTPRD,QDPR,FOXRED1,SLC1A2,SLC1A3,SOX10,NPAS3,SST,ABCC8,VPS13A,SYP,SYT5,TAC1,TAC3,MLST8,TRH,NTSR2,SLC17A7,KCNAB1,NETO1" Drug 3820_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "ASIC1,NLGN4X,AGT,ADGRF5,AMPH,AQP4,CDK10,ATP2B2,RUNX1T1,RAB33A,SLC24A2,STOML1,SULT4A1,NCOR2,INTS1,DLG4,TRAPPC9,DTNB,EFNA3,SRPK3,ELN,EIF1,LRRC17,MTSS1L,IGSF6,ATP8A1,FGFR1,FGFR3,FOXG1,AGAP2,SORBS1,PDLIM5,ZNF44,CPLX2,RND1,PRUNE2,TPPP,GRM7,HTR5A,KCND3,VWA5A,MSI1,BCO1,NCAM2,NF1,NPPA,PCBP3,PDE2A,RETREG1,TMEM255A,KHDRBS2,RGS10,RGS12,RIT2,CNKSR2,SLN,SORCS3,RIMS1,NPAS3,MAPK8IP3,ACSBG1,COBL,PCDHGA1,PCDHA5,TK2,TPM1,TUBB1,SLC13A3,SLC17A7" Drug 4631_DN Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "PDE8B,ATP2B2,ALDH7A1,CADM3,ADGRB2,BAIAP3,BTRC,CACNA1A,MAP7,CBFA2T2,SCARB1,CDH10,LARGE1,CNOT8,NMT2,AKAP7,CREM,CTNND2,MFAP3L,SMG7,ATN1,DTNB,HEYL,MTSS1L,SPEG,FOXG1,ZNF44,ZMYND11,SIGLEC8,GCNT2,CACFD1,SOX21,ICA1,DIPK1A,KCNF1,LIG4,MAPT,NEUROD1,NF1,OPCML,PPARA,PTPRB,PEX5,TMEM231,RAB3IL1,ATG16L1,KHDRBS2,RGR,FBXW7,SBF1,SH3BP2,FRMPD1,SLA,SLC1A7,FAM214B,SLC14A1,RBM34,TSNAXIP1,DIP2A,SYT11,ADGRL3,IQCE,CRTC1,THRA,TIMP4,TK2,TNS1,XRCC4,SPHK2" Drug 6674_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "DPF1,ACHE,PLA2G6,ADGRF5,AMT,EPB41L5,BCAS1,DDX3Y,ATP2B3,N4BP2L1,AZGP1,CALB2,SCARB1,CHRNB2,ZFYVE9,DNAJB5,SULT4A1,TCEAL2,SUSD5,PDE4DIP,CNTNAP2,SPOCK2,BRINP1,TRAPPC9,DYRK1A,EDN1,ING4,CEND1,F5,AGAP2,CSDC2,RUNDC3A,POLL,SCRG1,KCNB1,KCNN1,MDM4,AFDN,NCAM1,NCAM2,NF1,NOVA2,NRCAM,NTRK2,PFKFB2,MED1,PPP2R2B,LRRN3,PRPH,DCHS2,PTAFR,CCDC40,GAL3ST4,FOXRED2,SH3BP2,FRMPD1,SLC1A7,ZNF334,HECW1,PHLDB1,ADGRL3,SMG6,PHF24,ARHGEF12,DAAM2,RIMBP2,VAV2,NT5M,PARP6" Drug 4226_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "ARID1A,ADORA3,NME5,C1QTNF3,ANK3,PKP4,APP,GYG2,CACNB2,NEURL1,REPS2,MAGI1,FOXN3,QKI,SULT4A1,CNTFR,IFFO1,FEZ1,ERC2,PHF14,SRGAP3,SGSM2,CHRDL1,DYNC1I1,EDIL3,ETV1,AGAP2,ERAP1,SYT17,ATP8A2,PCDH17,GNAL,GPR17,ATXN2L,VSIG4,TJAP1,MAP2,MOBP,MSR1,LYRM9,OLR1,CLDN11,PDE3B,NECAB2,CEP41,PTN,PTPRN2,MARCH1,ENOX1,RGS4,KCNIP1,ASAP3,NTNG1,FBXO11,ZNF334,LIMCH1,TNIK,NFASC,SYN2,MCF2L,WWC1,TBCEL,DOCK9,THBS4,ICAM5,CA14,LAT2,KCNAB1,EPM2A" Drug 2327_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "ASPHD1,AP2A2,MRTFA,BIN1,CDC42BPA,APOC1,RGS20,CDK13,SLC2A11,SCAPER,GYG2,BAIAP3,SCARB1,ARHGEF2,SLIT2,RAB33A,LY86,WHRN,CRMP1,NCOR2,DZIP3,SDC3,RIMS2,NOS1AP,HP1BP3,C3orf18,EFS,VPS26C,F3,ACSL4,ZNF589,FOXG1,GABRA2,ADAM28,USP19,MSL3,GRIK5,TJAP1,ITPKB,MMP16,MOBP,LYRM9,ZNF862,CNOT4,NPR2,CDK18,PDE3B,GPR85,CDK14,RETREG1,SLC25A23,LRRN3,PRKAR1B,MAPK8,ELOVL2,ZSCAN2,RAB3A,RAD52,FRMPD1,BTBD7,ZCCHC24,MAPK8IP3,WSCD1,TCF7L2,THRA,TK2,XRCC4,GDPD5,KCNAB1" Drug 4121_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "ALK,GAS7,CDC14B,ASPH,BRINP2,CCDC181,ATP2B2,CFLAR,CHI3L2,CHRNB2,FADS2,WHRN,PDE4DIP,SDC3,NOS1AP,NTM,DMPK,CDON,ATN1,GPR153,FYN,GAB1,GABRA2,GFAP,GFER,RND1,POLL,GNAL,LPAR4,ATXN2L,HTR2A,SHISAL1,ITGA7,KCNN1,MMP16,MYT1,OPCML,CDK18,CAMKV,PLCD1,PPP1R1A,MAPK7,SNRK,RAB3IL1,RGS10,KLHL11,MYH14,RPS6KA2,EMID1,SYNDIG1,SCN8A,SH3BP2,DOCK10,SLC2A5,SMTN,PKNOX2,SMARCD3,NMNAT2,ZBTB43,LMO3,AJAP1,JMJD6,TPM1,TPM2,TRO,SLC30A3,NT5M,SSPN,JPH3" Drug 5747_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.02E-11 9.91E-07 5.63E-09 6.41E-08 69 197 "TRMT9B,PRX,SLC2A11,N4BP2L1,CACNA1I,BTRC,HAP1,CACNA2D2,CHRNA4,ABCG2,COL9A3,CSF1R,MICAL2,PHF14,ARHGAP24,SRGAP3,ARNT2,ATN1,EDN1,EDN3,PLXNC1,ELN,DMTN,ZNF549,CDKL3,OLFM1,FOXG1,C1orf61,ZNF44,SYT17,ATP8A2,INPP5K,POLL,PRUNE2,GPR17,PADI2,ICA1,SCIN,ITIH2,KCNJ5,LSS,MATN3,LYRM9,NDUFA5,NTRK2,PBX1,POLG,POU6F1,MINDY2,PPP2R2B,DCHS2,ACSS3,RALGDS,ZCWPW1,RNASEL,NEK11,LRRTM4,FRMPD1,ST6GAL1,PKNOX2,SLC9A5,KIF13A,IQSEC2,ATP10B,NACAD,ACSBG1,OBSL1,TRPC1,GAN" Drug CID000005917 pentylenetetrazol Stitch 2.19E-11 1.07E-06 6.05E-09 6.89E-08 52 130 "ABAT,ACLY,ADORA1,ADORA2A,ADORA3,CA4,CACNA2D1,TOX,DBI,SV2B,EXOG,STX2,ADGRV1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GALR1,GFAP,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM3,GRM5,HRH3,KCNA1,KCNN2,MEST,NPY,OGDH,PDYN,PENK,SLC36A4,PTCH1,SLC6A1,SST,SYN1,SYN2,MLST8,ZEB1" Drug 4710_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.23E-11 1.09E-06 6.05E-09 6.89E-08 64 177 "DPF1,ADD3,NME5,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,PDE4DIP,ARMCX2,DNAJC6,EFNA3,EFNB3,FAM13A,RASGRP2,TUBB4A,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLYR1,GLS,RAB40B,STON1,KCNH2,KIF5C,VWA5A,MAP2,MXI1,NAP1L3,NEK1,SERPINE2,SERPINI1,PIK3CD,PRPH,RAB3A,TTLL7,SH3GL3,SYBU,WDR47,CCDC88A,SMARCD3,LIMCH1,TNIK,ZCCHC24,SOX15,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 5945_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.23E-11 1.09E-06 6.05E-09 6.89E-08 64 177 "ADRB2,NME5,BIN1,MARK4,BMP7,BAIAP3,SPAG9,CLGN,WHRN,PDE4DIP,CTH,SEC14L5,ARMCX2,OPTN,EFNA3,FAM13A,TUBB4A,ATP8A1,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KIF5C,VWA5A,MMP17,NAP1L3,PCDH9,ENPP2,SERPINI1,PIK3CD,PLCD1,PRPH,TTLL7,RPS6KA2,SMPD3,SH3GL3,ASAP3,WDR47,PKNOX2,ZCCHC24,KIF21B,PEG10,SPTAN1,ELOVL4,RGL1,STX1A,STXBP1,ACSBG1,SYT11,VAMP1,ZEB1,HEY1,RUNDC3B,SSBP2,DNAJC12,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug 4112_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.25E-11 1.10E-06 6.05E-09 6.89E-08 63 173 "ADD3,ADRB2,NME5,MARK4,ST3GAL5,BAIAP3,USP2,CLGN,WHRN,AKAP12,PDE4DIP,ARMCX2,DNAJC6,TSPAN5,FRY,OPTN,EFNA3,EFNB3,FAM13A,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,KIF5C,VWA5A,MAP2,MEF2C,MXI1,NAP1L3,NEK1,PCDH9,SERPINI1,PIK3CD,GRAMD1C,PRPH,RADX,SH3GL3,ASAP3,WDR47,PKNOX2,CCDC88A,LIMCH1,TNIK,ZCCHC24,KIF21B,SOX15,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,HEY1,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 5594_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.25E-11 1.10E-06 6.05E-09 6.89E-08 63 173 "ADD3,ADRB2,NME5,APAF1,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,SRGAP3,EFNB3,FAM13A,STX2,ACSL4,TUBB4A,BAIAP2,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,RAB40B,STON1,KIF5C,VWA5A,MAP2,NAP1L3,NEK1,PCDH9,ENPP2,TMOD2,SERPINI1,PIK3CD,GRAMD1C,PRPH,RADX,SH3GL3,WDR47,PKNOX2,TNIK,ZCCHC24,KIF21B,ARHGAP26,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 3868_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.25E-11 1.10E-06 6.05E-09 6.89E-08 62 169 "ABHD6,ADD3,ADRB2,NME5,APLP1,ST3GAL5,BAIAP3,CDH18,CLGN,WHRN,PDE4DIP,ARMCX2,DNAJC6,TMCC2,EFNB3,FAM13A,RASGRP2,TUBB4A,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,GSN,KIF5C,VWA5A,LSS,MEF2C,MPP2,NAP1L3,NEK1,TMOD2,SERPINI1,PIK3CD,GRAMD1C,PRPH,PTAFR,RPS6KA2,SH3GL3,ASAP3,WDR47,FAM214B,TNIK,ZCCHC24,KIF21B,PEG10,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 6033_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "MRTFA,BIN1,PPFIA4,APLP1,PLA2G4C,CDK13,SLC4A4,ADAM23,CACNG1,CHI3L2,TAOK2,SULT4A1,WHRN,TCEAL2,NRG2,ARHGEF10,CNTNAP2,DOCK4,DGKG,CNIH3,RUSC2,DMPK,DTNB,RCAN2,RASGRP2,CEND1,ZNF589,HPCAL4,NSG1,FYB1,GCNT2,GJB1,GPD1,ATF7,C2orf72,MAP4,MEF2C,BCO1,TAGLN3,MYL3,NOVA2,NTRK3,KCNK10,GPR85,CDK14,SAMD9,PTX3,ZNF493,RGS4,RGS12,MYH14,PNMA8A,SCN8A,RASA3,SLC1A2,SLC1A7,SNCA,HECW1,INKA2,TBCEL,CUX2,TNS1,TRPM2,VIPR2,MICAL1,LAT2,MKRN3,SPHK2,PRDM2" Drug 2279_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "ADRB2,APC,SLC2A11,N4BP2L1,BAIAP3,CBFA2T2,NEURL1,CDO1,CLCN4,WHRN,CABP1,TCEAL2,CRMP1,PLCH2,DMPK,CDON,ATN1,ST8SIA3,MBNL2,EIF4G2,TENM1,VPS13B,RASGRP2,MTSS1L,EPHB1,KCNMB2,STX2,ERBB2,TUBB4A,KIAA1109,DLL3,OGA,FYN,SEPT9,C1QL1,GPER1,TJAP1,ITIH2,KCND3,KCNJ5,MAOB,MBP,PCBP3,PFKFB2,PLP1,POU3F4,MINDY2,SAMD9,PTPRN2,CCDC40,ENOX1,SLC1A2,SLC2A5,SOX2,ZHX3,THSD1,PHLDB1,TAC3,ROBO3,PCDHGA1,PSD3,THBS4,TNS1,TPM2,TRPC1,TUBB1,VAV2,ADAMTS9,SLC17A7" Drug 3810_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "MTUS1,AMPH,AMT,APAF1,APC,CDC14B,PRX,PDE8B,ATP1A2,ATP2B2,SLC2A11,N4BP2L1,PROM1,BMP7,CDK5R2,LDLRAD4,RUNX1T1,USP2,PLCH2,TOX,KIAA0319,DNAH9,MBNL2,ERBB2,EZH1,SEMA4D,DPYSL4,CPLX2,ALDH1L1,SRCAP,GPR75,GRM7,HPSE2,KCNH2,KCNJ5,MGAT3,AFDN,MOBP,NF1,NOVA1,NPTX1,NTRK2,PDE3B,LRRN3,PRKAR1B,SAMD9,PTAFR,KHDRBS2,RNASE1,RNASEL,FOXRED2,SH3BP2,SLC2A5,SHANK2,SLN,PDZRN3,SOX10,IZUMO4,INKA2,MAPK8IP3,MCF2L,TK2,RIMBP2,TNFRSF1B,TPM2,RUNDC3B,TUB,PARP6,HRASLS" Drug 7381_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "AMPD3,AMPH,CDC42BPA,APC,CDC14B,DNAH17,CFLAR,LDLRAD4,CALB2,CAMK2B,NEURL1,ADGRG1,CPS1,VCAN,DBT,RUSC2,DPH1,DTNA,DUSP9,ST8SIA3,FCF1,ING4,FGFR1,BAIAP2,CAMSAP1,SEMA4D,FYB1,ALDH1L1,GLYR1,GLRB,GNAO1,KCNF1,MAG,MMP16,MYO7A,NOS1,OGG1,CLDN11,PALM,GPR85,PLCD1,PMP2,PRKAR1B,TMEM104,PTHLH,TMEM231,ZNF671,PAQR6,MAPK12,TRA2B,FUZ,KANSL3,SMARCD3,RBM34,KDM4C,MAPK8IP3,PHLDB1,PLCB1,TCF4,TRIM2,SLC44A1,CABIN1,AMACR,VIPR2,WNT7A,ZNF711,UBE3B,TIGD6,SSPN" Drug 4839_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "NR0B1,PLA2G6,BIN1,APBB2,PDE8B,ADAM23,BAIAP3,RHBDL1,CDH2,CLGN,FOXN3,B4GALT6,CLCN4,ENTPD4,SNCAIP,NCAN,CTH,DCAF4,CYBB,RASSF2,TBC1D5,TMCC2,ATN1,RCAN1,SIDT2,EN2,VPS26C,KIAA1109,C1orf61,AGAP2,DCTN2,GPER1,PCLO,SPACA9,ATXN2L,TJAP1,JAK2,KCNH2,KCNJ3,KHK,ADAM22,BCO1,MSR1,MYT1,PLCD1,MBOAT7,MAPK7,PLPPR1,SYNDIG1,SALL1,ST6GAL1,CNKSR2,FAIM2,TSNAXIP1,SOX10,ZSWIM8,HECW1,CLSTN2,SS18,ACSBG1,SZT2,PCDHGA10,PCDHA6,CDK20,XRCC4,PRDM2,NT5M,ITM2C,HRASLS" Drug 4358_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "NDRG2,ADORA1,AGT,PLA2G6,LTBP4,FAM135A,TRMT9B,SEMA7A,APBA2,GAS7,AZGP1,ADGRB2,CDH8,CHN2,COL9A3,MYRIP,CRMP1,CHD5,DUSP9,SGK2,AASS,LPAR6,EPB41,EPHB1,KCNMB2,ERBB4,SPEG,APC2,CSPG5,GABRG2,ERAP1,GATM,ALDH1L1,GLI2,LILRB4,NR3C1,ATXN2L,HLF,SCRG1,KCND2,KCND3,KPNA5,MAN2A2,MSR1,TAGLN3,NPTX2,PCSK5,ENPP2,CAMKV,PLCD1,PLTP,PLXNB1,LRRN3,ENOX1,ZNF493,TMEM206,RPH3A,SLC1A7,PEG10,ZNF423,WSCD1,SYNE1,DOCK9,DNAH7,ICAM5,TNS1,UCHL1,LAT2,KCNAB1" Drug 5087_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-11 1.29E-06 6.82E-09 7.76E-08 69 198 "RALGAPA1,TRMT9B,PPP4R4,PDE8B,DNAH17,ASTN1,SLC4A4,SLC2A11,N4BP2L1,GYG2,LDLRAD4,FOXN3,VAX2,RAB26,CREB5,ARHGEF10,CNTNAP2,DTNA,ST8SIA3,EFS,CACNG2,FGF1,AGAP2,SORBS1,PDLIM5,GAD2,ERAP1,SEPT9,GLI2,GPM6A,GPM6B,SOX21,GUCY1A2,BACH2,ELOVL5,ICA1,IL6R,DIPK1A,KCND3,AFF1,MYH7,NOVA2,NRCAM,PALM,PDGFRA,MAPK8,GRAMD1C,TMEM231,RAD52,SH3TC2,C1orf54,KHDRBS2,KCTD17,IL17RB,AMBRA1,ST6GAL1,SHANK2,TMCC1,SOX2,ZBTB43,INKA2,MCF2L,TCF7,SYNE1,TRPC3,VSNL1,SPHK2,KCNAB1,NUP214" Drug 1020_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.71E-11 1.33E-06 7.00E-09 7.96E-08 68 194 "ASIC1,NDRG2,KCNAB2,FAM131A,ARNTL,CDK13,CAPRIN2,BMP7,ST3GAL5,SCAPER,GYG2,RAB29,KYAT1,ARHGEF2,PDE4DIP,ARMCX2,ZNF804A,SIDT2,EFNA3,EFNB3,EGFR,FHL1,DPYSL4,GPR153,FYN,DISC1,GNG4,FERMT2,STON1,KCNH2,KIF5C,L1CAM,MAPT,MPP2,BCO1,ZNF862,PRPH,PTCH1,ELOVL2,RIPOR1,RALGDS,FAM184A,RPS6KA2,EMID1,ZNF821,PPM1E,ASAP3,ANKRD6,ZNF365,SLC22A4,LIMCH1,KIF13A,ZCCHC24,MAPK8IP3,ELOVL4,STXBP1,COBL,ATP11A,PCDHA6,TMEM121,ZNF34,BHLHB9,RUNDC3B,TRPC1,DNAJC12,NDRG4,REEP1,MAP3K12" Drug 6609_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.98E-11 1.46E-06 7.66E-09 8.71E-08 63 174 "ABAT,ADRB2,SYT13,AMH,APAF1,EPB41L5,ARNTL,ATP1A3,NOL4,ST3GAL5,NRXN3,ENTPD4,ABCG1,VCAN,PDE4DIP,CNTNAP2,CTH,KIAA0513,DNAJC6,PLPPR4,CHRDL1,EFNA3,CEND1,TAOK3,DLC1,BAIAP2,CAMSAP1,SORBS1,FYN,GAD2,RND1,GLS,GSN,DIPK1A,KIF5C,LIFR,KITLG,PDGFRA,SERPINI1,RETREG1,PROX1,PRPH,SYTL2,PID1,ENOX1,RGS4,RGS7,FBXW7,SH3GL3,ASAP3,DOP1A,DOK5,THSD1,ELOVL4,RGL1,SYT11,VAMP1,SYT1,COBL,RUNDC3B,DNAJC12,KCNAB1,DPF3" Drug 1014_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 3.00E-11 1.47E-06 7.66E-09 8.71E-08 62 170 "ADD3,ARNTL,ST3GAL5,SCAPER,BAIAP3,SPAG9,CLGN,AKAP12,PDE4DIP,DOCK4,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,EFNB3,MBNL2,STX2,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,TDRKH,STON1,GRM8,PADI2,KIF5C,LSS,MITF,MPP2,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,SGK1,SH3BGR,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,NPL,RUNDC3B,DNAJC12,SLC17A7" Drug CID000003413 forskolin from Coleus forskohlii Stitch 3.06E-11 1.50E-06 7.76E-09 8.83E-08 238 1014 "ASIC1,ACHE,ACLY,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,NR0B1,AQP6,ARNTL,PDE8B,NCOA1,SLC4A4,SLC2A11,ALDH7A1,RGS9,HCN2,BMPR1B,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,MAP7,CCK,KRIT1,USP2,LRBA,CHGA,CHGB,ASIC3,CHRM1,CHRNA4,CHRNB2,CLCN3,CLU,MYL6B,CNR1,AKAP7,AKAP6,AKAP5,CREM,CRHBP,CREB5,HAPLN1,CSF1,PPP1R16B,CALY,PLCXD3,GPSM1,ARHGAP32,DAPK3,DCT,DRD1,EDN1,EDN3,EDNRA,EDNRB,EGFR,RGS17,CALCRL,TUBD1,EPHA5,ERBB2,PTK2B,TUBB3,TUBB4A,PPP1R1B,FGF1,ACTL6B,FGFR1,FGFR3,FOXM1,CAMKK2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GALC,GALR1,GAP43,CPLX2,GCK,TUBA8,MSTN,GDF9,SESN1,GFAP,PPARGC1A,CRCP,GNAO1,GNAS,PRLHR,MCHR1,GRK4,TUBA1C,RAPGEF4,GRIA1,PLCD4,GRIK1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,GUCY1A2,GUCY1B1,HRH3,TNFAIP8L3,HMGCR,HP,HPR,HTR2A,HTR5A,MYLK2,IGF1,IGFBP1,TUBB2B,KCND2,KCNJ3,AQP11,MBP,MITF,MMP16,MYH6,MYL3,MYO6,P2RY13,NF1,NODAL,NOS1,NPY,NPPA,NPR2,NUMA1,OPRL1,OXTR,P2RY1,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PDYN,PENK,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,MBOAT7,PTPA,PPP3CC,PRKACB,PKIA,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTCH1,PTHLH,PTH1R,RAP1GAP,RET,RGS4,RGS7,RGS10,RIT2,RYR1,RYR3,MAPK12,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,FNDC3A,SLC12A2,SLC14A1,SCN3B,SST,SSTR1,SSTR2,PLCB1,SYT4,TAC1,ALG1,TBL1X,AZIN2,LEFTY2,TK2,ACTR6,ZFP91,PIK3R5,CDK20,TRH,TTPA,TUBB2A,TUBB1,VGF,VIPR2,VSNL1,P2RY12,SLC38A1,TUBA1A,SCG2,PLD4" Drug ctd:D003561 Cytarabine CTD 3.07E-11 1.51E-06 7.76E-09 8.83E-08 156 598 "TTYH1,NDRG2,MTUS1,DISP3,BCAR3,CNIH2,RGS20,MARCH3,ADGRB3,BID,GYG2,CA12,CALB1,CALB2,PRC1,CCKBR,INA,LRBA,MAGI1,CHN1,JAM2,SLIT2,PPT2,CNR1,CNTFR,COL9A1,SLC4A8,C2CD2,HAPLN1,LRIG1,SLITRK5,ST18,MYADM,RASSF2,AIF1L,DBN1,SNAP91,PARD6A,SRGAP3,NTM,EXOG,ATN1,EDN1,ATL1,BSCL2,NCALD,FABP7,TUBB3,ST3GAL6,FLNC,SGIP1,TPK1,ST6GALNAC3,SARAF,MPP6,FYN,PHYHIPL,MEGF10,GAP43,GCNT2,GHR,GLS,TNRC6A,PSRC1,GPM6A,GPR19,STON1,GPER1,CNTRL,GRIA2,SOX21,GUCY1A1,CELF3,HAS2,HES5,KCNN2,MAP2,MATN2,LRP1B,MEIS1,SCAMP5,RSPO2,NELL2,NPY,NOVA1,DDR2,OLR1,PAX6,PCSK5,PDE1A,PDE4B,PDE1B,PFKP,ABCB1,SEMA5B,PLCB2,PLP1,PLTP,PMP22,LRRN3,PKIA,PRKCZ,PRPH,RELN,KLK6,SYTL2,PTH1R,PTPRZ1,RAB5B,RGS4,ZFHX4,GSTCD,ATP8B4,ST6GALNAC6,RTN1,CCDC112,LRFN5,SEC14L1,GALNT10,NTNG1,SLITRK3,SLA,EFHD1,SLN,LIMCH1,SNCA,RBM34,SOX3,SPATA7,ZNF423,RGL1,PRRC2C,TAC1,TAC3,ROBO3,TCF12,PSD3,TEK,ZFPM2,TGFBR3,TK2,RGMB,TST,FLRT2,WIPF1,GUSBP1,PCDH20,TCEAL7,STMN4,PRDM8,ADAMTS9,NAV2,CAB39L,ITM2C,SLC17A6,HNRNPA3" Drug CID000002376 AC1Q3ZOL Stitch 3.15E-11 1.54E-06 7.91E-09 9.00E-08 83 258 "ABAT,SLC12A5,ADORA1,ADORA2A,ADORA3,APOC2,BCS1L,CACNA1D,CACNA2D1,CACNB2,CALB1,CCK,SOCS6,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,CNR1,SLC32A1,BOC,DBI,DMPK,MED12,DRD1,DTNA,EEF1A2,GPHN,STX2,ADGRV1,ACTL6B,CSPG5,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNN3,MEST,NOS1,NPY,OPRL1,PDYN,PENK,PTCH1,RIT2,GLDN,SLC6A1,SLC6A11,SLC12A2,SST,JMJD6,TAC1,MLST8,ZEB1,ACTR6,TRH,PORCN,PRDM2,SLC17A6" Drug CID006857345 AC1OAGFB Stitch 3.28E-11 1.61E-06 8.21E-09 9.34E-08 144 540 "ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,AP2A1,AP2A2,SPOP,AMPD3,AMPH,BIN1,DGKZ,DGKD,SPTBN4,ARHGDIA,PLA2G4C,HCN2,SYNJ1,SYNJ2,BTK,CALM1,HIP1R,CCK,DGKI,REPS2,CDC42,ASIC3,CHRM1,EPS15L1,CLTA,CLTC,AKAP5,SDC3,PLCXD3,DGKB,DGKG,GIT2,SNAP91,DLG4,DNM1,DNM2,DNM1L,EDN1,EDN3,RASGRP1,EGFR,RASA4,BSCL2,EPB41,EPB41L1,EPB41L2,RASGRP2,ERBB4,ACTL6B,BAIAP2,AGAP2,AGAP3,SDCBP2,GAB1,GAP43,WASF3,MALT1,GNAL,GNAS,GNG3,GRK4,RAPGEF4,PLCD4,GSN,NXPH2,IGF1,SCIN,KCNA1,KCNA2,KCNA4,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK3,KCNQ2,KCNQ3,SYTL4,MATK,GIT1,OCRL,KCNK10,PDGFRA,PDPK1,TMOD2,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,EPN1,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,SYTL2,PTK2,RASGRF1,RDX,GSTCD,KCNIP1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,RASA3,SH3GL2,ASAP3,SLA,RPH3A,SLC8A1,ARFGAP1,SCN3B,FNBP1,SPTAN1,SPTB,NSFL1C,ABCC8,PLCB1,SYT1,MLST8,EXOC7,TBL1X,ICAM5,ACTR6,TMOD1,TRH,TRPC1,TRPC3,TUB,UBC,VAV1,PLPPR5,PLD4" Drug 5104_UP Flumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.41E-11 1.67E-06 8.33E-09 9.47E-08 69 199 "DPF1,ADCY2,ADORA1,NR0B1,APBB1,APC,BCAS1,PRX,ALDH4A1,CADM3,ADAM23,BMP7,MTMR3,MYRF,ADGRG1,FOXN3,LHX2,NRXN2,IFFO1,HAPLN1,NCOR2,CTNND2,CTIF,MFAP3L,AK5,RASGRP2,PTK2B,SORBS1,GAB1,ZNF44,GAP43,DISC1,LILRA2,GPR19,LPAR4,GRIK2,CACFD1,ICA1,IGFBP1,ITGA7,KCNN2,KCNQ3,MGAT3,MOBP,MX1,GPR85,RETREG1,ZSCAN2,KHDRBS2,GAL3ST4,RGS12,KCTD17,RNASEL,PNMA8A,ZNF821,RASA3,ST6GAL1,SLC2A5,SORCS3,SNCA,KDM4B,ZBTB43,MAPK8IP3,MLC1,TK2,TNS1,TPM1,VIPR2,MPPE1" Drug 3701_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.41E-11 1.67E-06 8.33E-09 9.47E-08 69 199 "ARID1A,ADORA1,AGT,ALK,DOC2A,BIN1,APOC1,RASL11B,ADGRB2,LARGE1,TAOK2,STOML1,CNTFR,TCEAL2,TENM4,KIAA0586,MAML1,RABGAP1L,DMPK,CDON,ATN1,EDIL3,SGK2,PLXNC1,EIF4G2,ELAVL3,LRRC23,ETV1,FGF1,FYB1,GAD2,NEU3,SRCAP,POLL,GNG3,GPR19,HSD17B1,IRF8,ITIH2,KIT,SMAD1,MAP2,MAPT,MARK1,SCAMP5,ADAM22,TAGLN3,NF1,CNOT4,OPCML,CEP41,WDR25,PTPRB,FAM120C,RGS10,RGS12,TCP11L1,SBF1,MRAS,SMARCD3,ZHX3,DDN,ASTN2,MCF2L,HIF3A,AP4E1,CADM1,RPRM,KLC2" Drug 4064_DN Corticosterone [50-22-6]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.41E-11 1.67E-06 8.33E-09 9.47E-08 69 199 "RALGAPA1,TRMT9B,AMH,AMPD3,AQP4,PPP4R4,ASTN1,ATP2A2,ALDH7A1,SYNJ2,CACNA1I,BAIAP3,CBFA2T2,LHX2,DNAJB5,CNTFR,AKAP5,NCOR2,ARHGEF10,DZIP3,GPRASP1,CTIF,BRINP1,DLG3,EFNA3,FAM13A,SUGP2,PLXNC1,AASS,IRAK4,LRRC23,MTSS1L,ST3GAL6,FGF1,FGFR1,CINP,GAB1,SEPT9,C1QL1,GNAL,GPM6A,TDRKH,HSF2,KCNMA1,MAPT,MATN3,MGAT3,AFF1,NOVA2,NUMA1,PLCD1,EPN1,PTPRB,FAM120C,RGS7,ARHGEF10L,SEC61A2,PPP4R3A,SLN,IQSEC2,MCF2L,TIAM1,TK2,R3HDM1,ZMYND8,VGF,ZNF74,REEP1,HPS4" Drug 4297_DN Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.41E-11 1.67E-06 8.33E-09 9.47E-08 69 199 "LTBP4,MRTFA,OGT,APC,RASL11B,MYRF,CFAP410,CACNA1A,CAMK2B,CHM,PLEKHB1,B4GALT6,WHRN,CPS1,PDE4DIP,DZIP3,MAML1,C2CD2L,PLPPR4,TRAPPC9,ATN1,RCAN1,DTNA,HIPK3,EPB41L1,DMTN,NCALD,FGFR1,ANKFY1,ERAP1,SYT17,SRCAP,GPD2,SOX21,DHX35,HSF2,ICA1,KCNB1,LIG4,ADAM22,ZNF862,NF1,OCRL,OPCML,PALM,PLXNB1,CEP41,GRAMD1C,RAB3IL1,RALGDS,PREX2,BTBD7,KIF13A,WDTC1,ZHX3,ZBTB43,TROVE2,THSD1,PHLDB1,SMG6,SYNE1,TNS2,CABIN1,ZMYND8,VIPR2,ZBTB14,SPHK2,MAP3K12,EMSY" Drug 7446_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.41E-11 1.67E-06 8.33E-09 9.47E-08 69 199 "ADD2,ADRA1D,SEMA6A,BIN1,ALDH4A1,SLC4A4,MPDZ,KSR1,MTMR3,BTRC,FOXN3,STOML1,CREM,ABCG1,SEC14L5,MFAP3L,RABGAP1L,OPTN,MRNIP,HSD17B14,OGA,SRCAP,GLS,GPER1,GPR37,ADAMTS13,GRM1,ITIH2,KCNN1,MAP4,MID1,MMP16,NEFM,NF1,NOS1,NOVA2,PALM,PDE4B,PPP5C,PRKCB,MAPK7,MAPK8,GDPD2,RIPOR1,ZSCAN2,RYR3,ZNF821,SLC1A7,SHANK2,ZKSCAN3,SMARCD3,SNCA,WDTC1,TSNAXIP1,IZUMO4,HECW1,ZC3H13,INKA2,ELOVL4,PHLDB1,VPS13A,CRTC1,KCTD2,SEZ6L,VAV1,VSNL1,TFIP11,STMN4,KCNAB1" Drug ctd:C029297 vinylidene chloride CTD 3.88E-11 1.90E-06 9.41E-09 1.07E-07 326 1485 "SERPINA3,ABAT,KCNH8,SYN3,NDRG2,RNF157,ADD2,ADD3,CDC7,KIDINS220,HECW2,OSBPL1A,OSBPL6,ADGRF5,C1QTNF4,CEP126,CDC42BPA,ANK2,ANK3,APAF1,APOC1,CACHD1,APOC2,AQP4,AQP6,IGDCC4,ARRB2,ASPA,NCOA1,ALDH4A1,ATP2B2,ATP6V0A1,BCL7A,CFLAR,PROM1,BMPR1B,ST3GAL5,SYNJ2,C1QC,CA4,CA8,CACNB4,CALB1,CAMK2D,VSTM2A,PRC1,CLDN10,LDB2,ENTPD2,MYOM2,REPS2,CDC25B,LRRFIP1,LARGE1,CDO1,FOXN3,PLEKHB1,MS4A7,CHRNA4,SLIT2,SLC22A6,NGEF,FBXO7,FADS2,MAP4K4,LY86,CNTN1,SLC4A7,GAL3ST1,CP,SLC35F1,PNKD,AKAP12,GDA,CSF1,LRIG1,ATRNL1,IPCEF1,SIPA1L1,PPP1R16B,ERC2,UBXN2A,CTH,CYBB,TCAF1,ACY3,DGKG,SIRPA,DBT,DNAJC6,MFAP3L,CEP170,SACS,KBTBD11,DUSP9,EBF1,SNX29,ATL1,SGK2,RASGRP1,TMTC1,FRY,OPTN,SH3GLB1,AASS,PLEKHO1,ENO2,RCAN2,DMTN,GPHN,DENND4A,IGSF6,ETV1,F3,FABP7,SH3YL1,TUBA1B,TAOK3,EFEMP1,DLC1,FCGR1A,CHST15,FCGRT,FGF1,FGFR1,FGR,FOXM1,FLT1,NOP56,NBEA,SMC2,HVCN1,FAM49B,TPK1,CELF1,FUT9,FYB1,DENND2A,GALC,NEK6,MTHFD2,SYT17,ACSS1,GATM,ALDH1L1,GFRA1,FREM1,GHR,PPARGC1A,GK,HPGDS,GLDC,DBF4,GLS,GLUL,AIFM3,RAB40B,LNX1,PSRC1,ADGRA3,CNDP1,GPM6A,GPR34,PCLO,TPPP,MFSD2A,FAM107A,HBA1,KLF12,BACH2,HLF,HMGCL,HP,AGFG1,IGF1,IGFBP1,IL11RA,INPP5B,ITGAM,KCNC2,KCNJ10,KCNJ16,KCNK1,KHK,L1CAM,LIFR,SFXN5,MAOB,MAP2,MAP4,MARK1,AQP11,MEIS2,MGAT3,KITLG,MN1,SESN3,MSRA,MTTP,MYO7A,NFIA,ALDH1L2,NFIX,VWA2,NPR2,P2RX7,TREM2,PDE1A,PDE4D,PDGFRA,PFKFB3,PFKFB4,PFKP,PGAM2,ANLN,SNX10,PLCL1,PLEC,SMOX,PLXNB1,SEPT4,EPB41L4B,IRX1,PPARA,PPP1R1A,PPP2R2B,RANBP3L,PRKCB,PRKCZ,GDPD1,MASP1,SLC22A23,PTH1R,ELOVL2,SPDL1,PTPN13,PTPRB,PTPRE,PTPRO,QDPR,RAP1GAP,OXR1,RASGRF2,BEND5,VEPH1,SLC6A15,RGS4,RGS10,NUDT11,ZFHX4,RNH1,LGI2,SUGCT,PRR5L,STK32B,LRRK2,LGR4,PTGR2,ATXN1,SCN4B,SCP2,ASRGL1,RASA3,SH3BP2,PPP1R9A,DOCK10,SHMT2,ST8SIA1,ANKRD6,NUBPL,CLSTN1,SLA,SLC8A1,SLC11A1,SLC12A4,SLC15A2,EFHD1,SLC22A4,LIMCH1,TNIK,UNC5B,BEX1,IQSEC2,DDN,PBLD,EPB41L3,APOM,SEPT8,RGL1,ADHFE1,KANK1,SULF2,MTCL1,MCF2L,TBCEL,PSD3,NSD1,TEK,ZMAT3,TMPO,BEX4,TNFRSF1B,TNS1,TP53BP2,TPM4,AMACR,TRPC1,PPIL6,CA14,CADM1,DNAJC12,MICAL1,P2RY12,NPDC1,SLC13A3,LMAN2L,SEMA3B,NAV3,PLD4,FAM13C,DOCK8,PHTF2,FBXO36,ZDHHC20,SSPN,CPNE4" Drug 6993_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.90E-11 1.91E-06 9.41E-09 1.07E-07 64 179 "ABHD6,ADD3,ADRB2,NME5,MARK4,BMP7,ST3GAL5,BAIAP3,SPAG9,CLGN,AKAP12,CRY2,PDE4DIP,CTH,KIAA0513,ARMCX2,DNAJC6,SIDT2,OPTN,EFNA3,EFNB3,ENO2,F3,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,STON1,RNFT2,PADI2,KIF5C,MAP4,MAPT,MITF,NAP1L3,PCDH9,SERPINI1,PIK3CD,PLCD1,PRPH,SH3GL3,SYBU,WDR47,CCDC88A,SMARCD3,ZCCHC24,KIF21B,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7" Drug ctd:D012834 Silver CTD 4.14E-11 2.03E-06 9.96E-09 1.13E-07 412 1958 "TTYH1,ABAT,ADAR,FMNL2,DSCAML1,RNF157,USP31,ADORA2A,UNC5A,ADORA3,NLGN4X,SLC24A4,AP2A1,AGT,SEMA6A,ALCAM,BCAR3,CARNS1,PCDH10,DOC2A,AMPD3,ANK2,LCORL,PARG,EPB41L5,PHYHD1,BCAS1,APP,SHTN1,SEMA4G,MADD,TMEFF1,ARHGAP5,ARNTL,PLA2G4C,ASCL1,RASL11B,DDX3Y,DYNLL1,ATP1A2,RIPK1,BCL2L2,BID,CFLAR,PROM1,KSR1,C5,RAB29,CACNA1A,CACNA1B,CACNA2D1,THSD7A,PTBP2,NGB,CBR1,AIFM1,SCARB1,SYNGR3,LONRF2,ZNF445,UBE2L6,FOXN3,SOCS6,CHM,RAB3C,JAM2,SLIT2,NRXN2,CLU,FAM189A2,CNR1,WHRN,COL4A5,MYRIP,ZNF521,IGDCC3,CP,NECTIN3,CREB5,AKAP12,CRY2,GDA,TENM4,VCAN,SOCS5,SLITRK5,UBXN2A,CTNND1,ST18,HDAC9,RIPOR2,PHF19,CENPL,ACY3,MATR3,DGKG,DNAJC6,ZNF804A,ZEB2,HEPH,LYPD1,SNAP91,PARD6A,SV2B,SRGAP3,CHRDL1,DLG4,EXOG,OLIG1,HS3ST2,CDON,DNM2,CPEB2,SLC25A18,RCAN1,ARRDC4,E2F5,USH1C,EEF1D,CACNG7,SH3GLB1,EFNB3,MBNL2,RASA4,AASS,ELN,EMX2,HSD17B14,TUBD1,RCAN2,LRRC17,MTSS1L,RABEPK,RAB9B,EPS8,ERCC2,RCSD1,EXTL1,EYA1,MRVI1,REEP2,WAC,ZIC4,FCGR1A,FKTN,SLC9B2,PRKAG2,POLK,MEX3B,CAP2,AGAP2,EVL,ATP13A4,FLT1,SYT3,AKAP3,ZBED3,USP16,UFM1,TRIM16,PRELID3A,DOT1L,FYN,MEGF10,GAB1,GABRG2,IQGAP2,SYT17,WASF3,MSTN,CYP46A1,GFRA1,RUNDC3A,RND1,SPIN1,GLI2,GLS,LOXL3,GPM6B,LPAR4,CNTRL,GRIA2,SERP2,ADAMTS8,CIT,TMEM25,RNFT2,HAS2,TOX2,MAN1B1,HRH3,SCRG1,HMX1,USP51,IFI16,IGF1,LRRCC1,INPP1,INSM1,ITGAV,SLC35G1,KCNN2,KIF5C,LAMP2,LIMS1,LMO2,NCOA7,LSS,MAG,NAT8L,MAOB,MAP2,MAPT,MAT2A,LRP1B,SHC3,MEF2C,MEST,KITLG,SCAMP5,PPM1L,MMP16,MN1,MOV10,MSRA,MT1M,MT3,MTTP,MX1,MYCN,LAYN,P2RY13,NBL1,NCF2,NDP,NFE2L2,NFIX,NME4,NOS1,NPR2,NRGN,P2RX7,PAX6,PDE1A,PDE1C,PDE2A,PDE4A,PDE4B,PDGFRA,PDPK1,GPR173,GPR85,SERPINI1,SEMA5B,PIK3C2A,PIK3R1,XRN1,TMEM38A,SMOX,PLTP,PNMA3,SH3KBP1,POU3F2,PPP1R1A,NKAIN4,PRKCZ,MAPK3,MAPK8,MAPK9,SLC22A23,GDPD2,TMEM104,QRICH1,PTHLH,PTK2,PTN,PTPRE,FAM120C,RAB5B,PID1,IQSEC3,FAT4,ZCWPW1,RASGRF1,FEZF2,RDX,SLC6A15,ZMAT4,RFX4,RNASE1,ZFHX4,MCMBP,RIMKLA,FAM161B,PAQR6,SOX8,RXRA,SEMA6D,ATXN7,SCN3A,PEAR1,TRIM46,SELL,ASAP3,FHOD3,ST6GAL1,CCDC92,URGCP,PREX2,PPP4R3A,PKNOX2,SLC8A2,RADIL,SLC11A1,SHANK2,SCMH1,ELMO2,BTBD7,ATF7IP,SLC22A4,SNAP25,SNCA,PDZRN3,SOX1,MYT1L,SOX2,SOX3,ENKUR,SPP1,NPAS3,ATP10B,ITPRID2,SST,NXT2,MAPK8IP3,ELOVL4,RGL1,KANK1,STXBP1,GSE1,ACSBG1,ABCC8,SYN1,SYN2,SYP,TAC1,TAC3,TACC1,DNMBP,ADGRL3,WWC1,TCF7L2,ZEB1,TCF12,SYNE1,TMEM151B,PSD3,TNS2,ARHGAP9,CCDC173,VWCE,TF,ZFPM2,AKTIP,CDH22,SLC44A1,TMOD1,TNR,TPD52L2,TPM1,IL34,TRIO,AMACR,TRPC1,TRPS1,SSBP2,RFTN2,TTPA,CLHC1,UCHL1,FLRT2,WIPF1,KLC2,LGI4,ZIC1,ZIC2,ZIC3,MKRN3,LYPD6,POLR3H,DPYSL5,PLPPR5,PMEPA1,RGMA,PRDM8,RNF103,ADAMTS9,SIGLEC10,SLC17A7,PPP1R3F,FZD3,RTN4,CAMK1G,ADAMTSL3,PIANP,NETO2,NETO1,RNF146,SOCS4,ST8SIA2,GAN,PRRT4" Drug CID000000764 guanine Stitch 4.23E-11 2.07E-06 1.01E-08 1.15E-07 216 903 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,NME5,AMPD2,AMPD3,OGT,PKP4,CNTNAP1,APC,ALS2,MADD,CASK,ARHGDIA,ARRB1,ARRB2,PDE8B,ALDH7A1,CACNA1E,DIRAS1,NGB,TRIM41,ARHGEF25,CCK,CCKBR,P2RX6,ARHGEF1,CD38,LRBA,ARHGEF2,CDC42,MAGI1,IGFN1,CHN1,CHRM1,RAB3C,NGEF,ARHGEF6,GDA,RGS6,ARHGEF10,RASGEF1C,PLCXD3,CTNND1,GPSM1,DOCK4,ARHGAP24,GIT2,SLC29A4,DOCK2,DRD1,ABI1,GNE,E2F5,USH1C,EDN3,EDNRB,EEF1A2,RASGRP1,OPTN,RASA4,LPAR6,BSCL2,TUBD1,RASGRP2,EPS8,RRAGB,GMPR2,TUBB3,TUBB4A,POLK,AGAP2,AGAP3,RASL10A,GAA,RAPGEF6,GALR1,IQGAP2,GART,GATM,TUBA8,DHRS4,RND1,POLL,GNAL,GNAO1,GNAS,GNG3,GNG4,LPAR4,MCHR1,TUBA1C,RAPGEF4,GRB10,RAPGEF1,GRIA1,GRIA2,GRIA4,PLCD4,GRID1,RFFL,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,RABL2A,GABARAPL2,TUBB2B,GIT1,N6AMT1,P2RY13,NCF2,NEUROD1,NF1,NFE2L2,NNAT,NME4,NPY,OGG1,OPRL1,P2RX7,P2RY1,PAK3,PDE2A,GNG2,PENK,GPSM2,PLCB2,PLCD1,PMP2,RASGEF1B,PRKACB,MAPK3,MAPK8,MAPK9,MAPK10,DIRAS2,MASP1,PSMA6,RAB3A,RAB5B,RALGDS,RASGRF1,RASGRF2,RGS4,RGS7,RGS12,ARHGEF10L,RIT2,RNASE1,RIC8B,RNH1,RTKN,FNIP1,SELL,MRAS,SUPT20H,RASA3,SHMT2,PREX2,RAB3GAP1,ARFGAP1,ZKSCAN3,NMNAT2,MYCBP2,MCF2L2,SST,SSTR1,SSTR2,RGL1,ARHGEF9,NUDT10,PLCB1,MLST8,MCF2L,EXOC7,TBL1X,DOCK9,ARHGEF12,SIRT1,TMEM121,TIAM1,TK2,BHLHB9,SMUG1,TRIO,NEIL2,TSC1,TSC2,TUBB2A,TUBB1,UGT8,VAV1,VAV2,VIPR2,P2RY12,SLC26A10,PRTFDC1,TUBA1A,PLD4" Drug 5683_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-11 2.17E-06 1.04E-08 1.18E-07 69 200 "NDRG2,AP2A2,PLA2G6,C1QTNF3,DOC2A,APBA2,SGCE,CACNA1I,CDK5R2,CACNG1,KALRN,HAP1,FOXN3,CHRNA4,LY86,WHRN,CRHBP,SUSD5,IPCEF1,CHD5,NCAN,CNTNAP2,ARHGEF4,RIMS2,TRAPPC9,EGFR,MRNIP,NRN1,FYB1,SRCAP,GNAL,GPER1,GRK4,GRIA1,GRM1,SOX21,C2orf72,KCNH2,KCNMA1,ADAM11,MOBP,NTRK3,PCDH9,ENPP2,PLCL1,EPN1,PLP1,SEPT4,MINDY2,PRKCB,ZNF493,TRIM68,KCTD17,TTLL7,CCDC102B,SELL,HKDC1,SNCA,SYT5,DOCK9,HIF3A,TEX15,TIMP4,NTSR2,BEST1,CLIP2,SPHK2,ADAMTS9,SEMA3B" Drug 4837_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.42E-11 2.17E-06 1.04E-08 1.18E-07 69 200 "ADORA3,AP2A2,KIAA1324,APC,APP,AQP4,ADGRB1,KSR1,CALB2,HAP1,ADGRG1,FOXN3,FAM149A,CABP1,IFFO1,HAPLN1,AATK,OSBPL3,NCAN,SNPH,DYNC1I1,ATN1,DSCAM,USH1C,EDN1,LRRC23,RASGRP2,PIPOX,PTK2B,C1orf61,FYB1,HBS1L,GNAL,GPD1,NR3C1,WIF1,HRH3,ATXN2L,ITGA7,ITIH2,KCNJ5,KHK,KPNA5,MEF2C,TAGLN3,NCAM1,NPTX1,NTRK3,OPCML,ENPP2,SERPINI1,CAMKV,PPP2R2B,LRRN3,CNTLN,RGS12,FNDC3A,IGSF9B,SNAP25,KDM4B,SCN3B,PEG10,IQSEC2,ACSBG1,SYT5,WSCD1,PCDHGA10,PSD3,NDRG4" Drug 7480_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-11 2.17E-06 1.04E-08 1.18E-07 69 200 "KDM5D,SEMA6A,GAS7,FAM131A,PPP4R4,CDK13,MARK4,ALDH4A1,MTMR3,CFAP410,CALB2,CAMK2G,SYNGR3,CHRNB2,TAOK2,CREM,MICAL2,DZIP3,TBC1D5,MFAP3L,MED24,EXOG,DNM1,CNNM1,MRNIP,EPB41L1,EZH1,ACSL4,SRCAP,USP19,GLYR1,RAB30,GRIN2C,RNFT2,TJAP1,MAP4,MDM4,MEIS1,MIA2,NELL2,NF1,NOVA1,NUMA1,SERPINI1,PLCD1,PRKAR1B,PRPH,PTAFR,RIPOR1,CEP97,CCDC25,RPS6KA2,SLC1A7,WDTC1,SPTAN1,STX1A,IQCE,KIAA0930,SZT2,CRTC1,PLPPR2,XRCC4,ZNF45,NDRG4,TFIP11,SEMA3B,NAV2,UBE3B,NUP214" Drug 6771_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-11 2.17E-06 1.04E-08 1.18E-07 69 200 "SYN3,MRTFA,APBA2,MARK4,ALDH4A1,ADAM23,CFLAR,LDLRAD4,HAP1,ARHGEF1,NEURL1,CHGB,CHN2,CHRNB2,CLCN4,STOML1,GREB1,NOS1AP,DMPK,TRAPPC9,GNE,EFNB3,CELSR3,SUGP2,TNK2,VPS13B,TUBB4A,FGFR1,FHL1,C1orf61,GAP43,SIGLEC8,GLYR1,PRUNE2,GPER1,STMN2,CACFD1,KLF12,IL6R,KCNJ5,KIT,MAP4,MBD1,MMP16,NCF2,NRGN,PALM,PDE1C,PDE4A,PENK,MTRF1L,PLXNB1,NECAB2,TNPO2,POU3F4,C1orf54,RYR1,ASIC4,AMBRA1,SLC14A1,SLN,SOX2,ARHGEF9,SLC44A1,TMOD1,TNS1,PLPPR2,NT5M,SSPN" Drug 3261_UP Lysergol [602-85-7]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.59E-11 2.25E-06 1.07E-08 1.21E-07 68 196 "ABHD6,C1QTNF3,TRMT9B,PPP4R4,RGS20,ARRB2,SLC4A4,ALDH7A1,CFLAR,CACNA1I,BTRC,CFAP410,CA12,KYAT1,CNTFR,AATK,ATRNL1,RIMS2,SEC14L5,BRINP1,MFAP3L,DMPK,HIPK3,VPS13B,DMTN,LRRC23,CDHR1,CEND1,F5,FGFR1,C1orf61,GAB1,GAD1,ATP8A2,GLYR1,GLS,GPER1,ICA1,IL12A,KCNH2,MAOB,MDM4,MID1,GIT1,NF1,NNAT,NUMA1,OGG1,SERPINE2,RETREG1,STRN3,NECAB2,PRKACB,MAPK10,PRPH,RAD51D,GAL3ST4,ZFHX4,ITSN1,PREX2,TSPYL2,SPART,CAMTA2,SLC19A3,TMOD1,GDPD5,TIGD6,RNF146" Drug 4490_UP Piretanide [55837-27-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.59E-11 2.25E-06 1.07E-08 1.21E-07 68 196 "KIDINS220,MTUS1,AK2,BEGAIN,APAF1,EPB41L5,BCAS1,CDK13,ATM,ATP2B2,CADM3,ADAM23,BMPR1B,GYG2,CACNG1,CBS,CHRNB2,TAOK2,ABCG2,DNAJB5,HOMER3,COL9A3,NCOR2,NOS1AP,CTIF,SMG7,EXOG,DMPK,ETV1,PTK2B,FOXG1,AGAP2,FYN,GABRA5,LYVE1,GPM6A,ATF7,ITIH2,KCNN1,LSS,SMAD1,NEFM,NF1,NPR2,OMG,CDK18,GPR85,PFKFB4,PIK3R1,NLE1,SPATA6,PPP2R2B,PKN2,MAPK7,SNRK,EMID1,RPS20,SCN2A,DZIP1,SHANK2,TNIK,HECW1,NPAS3,SEMA4A,MCF2L,SLC13A3,KCNAB1,GAN" Drug ctd:C006703 benzo(b)fluoranthene CTD 4.93E-11 2.42E-06 1.14E-08 1.30E-07 340 1564 "SERPINA3,NCKAP5,PLEKHG5,ADCY5,ADCYAP1R1,ADD3,ERMN,ADORA3,NME5,SORCS2,ADGRF5,SEMA6A,ARHGAP20,GOLGA7B,BIN1,ANK3,SEMA7A,LCORL,ANXA7,CPNE5,LGR5,PPP4R4,ARNTL,ASGR1,ASPA,MARK4,ASPH,NUMB,ATP2A2,ADAM15,BARD1,BCHE,RGS9,GPR146,C5,MMD2,CA8,THSD7A,HAP1,NGB,CAMK2G,PRC1,USP2,CD38,ENTPD2,CIART,MS4A7,RAB3C,ARHGAP22,CLTB,ABCG2,MAP4K4,HOMER3,AKAP7,ABI3BP,CP,NSL1,NECTIN3,CLOCK,CREM,ANKRD44,GDA,AATK,CSF1,CSF2RA,FEZ2,MICAL2,OSBPL3,RASGEF1C,CTH,GREB1,DCAF4,CX3CR1,NOS1AP,MYADM,FGFR1OP2,PHF19,KCTD8,BRINP1,DBI,DCC,ELMSAN1,GSDME,OLIG1,SLC29A4,DYNC1I1,NR1D2,FAM57B,ARRDC4,ABCC5,EDIL3,EDNRB,SYT15,KLHL5,TMTC1,FAM13A,EGFR,KMT5B,RASA4,AASS,LPAR6,SRPK3,BSCL2,EML1,EPB41,DMTN,RCSD1,ADGRV1,F3,REEP2,ABCA8,FAM198B,TUBA1B,PTK2B,FGF1,FGFR3,POLK,HPCAL4,ZMYND15,SMC2,APOPT1,TRIM16,TPK1,NSG2,CGREF1,NSG1,STAU2,PNMA2,AP4B1,OGA,SDCBP2,GAA,GALNT15,GAP43,SRRM4,CPLX2,MYOZ2,GCK,GPR162,PCDH17,LYVE1,GJB1,RND1,GLDC,SPIN1,TOX3,AIFM3,HTATSF1,PSRC1,ADGRA3,GPD1,CCDC184,STON1,STMN2,GRB10,DIDO1,PLCD4,SERP2,GRIN2C,PTPN5,TMEM25,BVES,MFSD2A,FAM107A,SLC2A6,ATOH8,NXPH3,HLF,HMGB1,HMGCR,CFAP126,CPT1C,HSP90AA1,CELF5,HTR2A,ICA1,IFI16,IGF1,IGFBP1,NKD1,DISP2,TUBB2B,ITGA7,KCNB1,KCNH1,KIT,STMN1,LIG4,LSS,ZFYVE27,MAT2A,LDLRAD3,TM6SF1,MDM4,MEST,KITLG,PPM1L,CD200,BLOC1S2,MSR1,THYN1,DDX25,LAYN,NEXMIF,P2RY13,NNAT,PCBP3,NRCAM,NRDC,NRGN,P2RX7,TREM2,PBX1,PDE2A,PDE4A,TMOD2,CYTL1,PFKFB3,PGAM2,ABCB1,ANLN,PLCD1,PLEC,PLIN1,PLXNB1,PMP22,PPP2R2C,MAPK10,SLC26A11,LAMA1,GDPD2,MTMR10,PTPRB,PTPRG,TTC13,TUG1,TMEM255A,RAP1GAP,SUSD4,VEPH1,FIGN,RGS12,TTLL7,LGI2,ROBO2,TMEM206,GLDN,RIMKLA,EMID1,MEG3,HUNK,RTKN,NCBP3,SCN7A,PEAR1,SELL,SHC4,HKDC1,MAGI3,FHOD3,R3HDM2,DZIP1,ZNF365,EPN2,RUFY2,FAM214B,SLC8A1,ARHGEF40,SLC12A4,ARFGAP1,SLN,MAST1,PALLD,FAM126B,SCN3B,TRERF1,SOX11,SPP1,UNC5B,ZNF423,TAB2,CLSTN2,THSD1,INKA2,SEPT8,SULF2,SEPT3,STXBP1,SYNE2,PLCB1,SYN2,SYT1,COBL,ANKRD12,KAZN,TAF6,EHBP1,TCF7L2,TCF12,SZT2,PCDHGA9,PCDHB10,NSD1,PCDHAC2,GPRIN3,SLC35G2,AHCYL2,TF,ZMAT3,CDH22,THRA,TIAM1,TIE1,HEY1,TNS1,RASD2,ZNF346,ZMYND8,CA14,LRTM2,TUBB2A,TMEFF2,AMOT,UCHL1,RBFOX3,FMN2,SLC26A10,REEP1,PROCA1,PARP6,GDPD5,TMEM178A,HPS4,RGS7BP,FAM13C,TTC7A,SSPN,AAAS,PIANP,CPNE4" Drug ctd:D004113 Succimer CTD 5.01E-11 2.46E-06 1.15E-08 1.31E-07 287 1278 "CPNE2,ACHE,NDRG2,ADD3,CDC7,GRAMD1B,AGT,ALAD,ALCAM,BBOX1,AMPD3,CDC42BPA,ANK3,SEMA7A,FGD2,APOC2,PPFIA3,USP37,SEMA4G,CASK,CADPS,PDE8B,ASPH,PTCH2,ATP2B1,N4BP2L1,BCL7A,NRP2,BLM,CFLAR,FUBP1,SCAPER,JAZF1,OSGIN2,CACNA1A,CACNA1B,CAMK2D,CANX,CAPN3,CAST,SPAG9,USP2,SLC16A4,CD86,CBFA2T2,CDH10,ZNF445,CDO1,UBE2L6,CHN1,LHX2,NRXN3,CLU,CLTA,CLTC,HECTD1,ARHGEF6,SLC4A7,CP,NECTIN3,RBM39,ANKRD44,GDA,ABCG1,CSF1,FEZ1,MICAL2,PDE4DIP,CST3,DZIP3,SDC3,CTH,RIMS2,ST18,CX3CR1,CYBB,HDAC9,ZFYVE16,RASSF2,TBC1D5,ACY3,MATR3,AIF1L,ZNF804A,ZEB2,MFAP3L,CEP170,MAGI2,ZC3H11A,DDX46,ALKBH8,SACS,MTX3,KBTBD11,DMPK,NR1D2,CASP8AP2,PDCD6IP,RCAN1,ARRDC4,EDIL3,WDPCP,EEF1D,SH3GLB1,PHF20L1,EGFR,MBNL2,EGR3,ENO2,EPB41L2,ERBB4,IGSF6,ANKMY1,TLR7,F3,FAM198B,ACSL4,PRAM1,ATP8A1,ST3GAL6,FCGR3A,SLC9B2,FGF1,SYNCRIP,ZMYND15,SMC2,USP16,PDLIM5,FAM49B,TRIM16,ZNF605,MPP6,FYN,NCKAP1,ERAP1,ALDH1L1,SESN1,ADAM28,MALT1,BRD8,HPGDS,ZNF638,GNG4,GPD2,MCHR1,NR3C1,GSN,KAT7,GUCY1B1,RASSF8,TOX2,PADI2,IFI16,IGF1,IGFBP1,NKD1,SCIN,IL6R,IL6ST,ITGAM,ITGAV,JAK2,KIFC3,KIT,STXBP5,LIG4,LIMS1,SYTL4,LSS,PACRG,SMAD9,GPR155,AQP11,LDLRAD3,MEF2C,MID1,MOV10,LAYN,NFE2L2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,SETD4,PDE1A,PDE4B,ENPP2,GPR85,ABCB1,SERPINI1,PIK3R1,ZFYVE21,SLC25A23,STRN3,RC3H2,PILRA,MINDY2,TATDN3,PRKCB,MAPK8,PXK,SPDL1,ZIK1,TUG1,USP47,RBBP6,RBBP8,ZDHHC14,REV3L,RNASE1,NUDT11,ZFHX4,MYH14,RPS6KA2,HUNK,RTN1,ATXN1,SFPQ,DOCK10,CHD9,ST6GAL1,LIMS2,ZNF430,SLC8A1,CCDC88A,SLC11A1,SLC20A2,SLC22A4,FAM126B,KIF21B,SPP1,KDM4C,ZC3H13,ZBTB43,RBM26,SRPK2,TROVE2,SMOC1,STAC2,SULF2,FGD4,SYN1,ANKRD12,SEMA4A,TCF4,TRIM2,TCF12,NSD1,SIK3,TF,AKTIP,SLC44A1,DDHD1,TLR4,ZFP91,TMPO,TNFRSF1B,PRRT1,NR2C2,PDSS1,STXBP4,TRPS1,ZMYND8,RFTN2,TTC3,USP1,MGAT5B,VLDLR,WIPF1,SLC13A3,AGMO,AMZ1,PMEPA1,PRDM2,EVI5,NAV2,FIP1L1,FAM13C,RTN4,HNRNPA3,JMJD1C,NLRP3,TTC7A,ADAMTS10,SPATA13,SENP7" Drug CID000004587 AC1NFC6P Stitch 5.10E-11 2.50E-06 1.17E-08 1.33E-07 56 148 "PCDH10,ASCL1,MYOM1,FGF17,GPC2,CBS,MYOM2,CDH8,GAL3ST1,PLCXD3,OLIG1,DRD1,EN2,OLIG2,FGFR1,GALC,NCKAP1,GFAP,PLCD4,TOX2,HMGCR,MAG,MBP,MOBP,MSRA,MYH3,MYT1,NCAM1,NPTX2,NTRK3,IGSF11,PAX6,PCDHGC3,PDGFRA,PENK,PLCB2,PLCD1,PLP1,PMP2,PCMTD2,HES6,BCAN,SPP1,PLCB1,TCF7,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,HIF3A,TNR,HEPACAM,PCDH20,MSRB3" Drug 4072_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.13E-11 2.51E-06 1.17E-08 1.33E-07 64 180 "DPF1,ABAT,ADRB2,MTUS1,SHROOM2,ARNTL,BRINP2,NOL4,ST3GAL5,CDK5R2,HIP1R,USP2,SYNGR3,CHN2,ABCG1,SUSD5,PDE4DIP,CTH,PLPPR4,SRGAP3,EFNA3,RGS17,TUBB4A,TAOK3,TESK2,FGFR3,BAIAP2,DPYSL4,SORBS1,CYP46A1,PCDH17,RND1,STON1,GUCY1B1,DIPK1A,VWA5A,MMP16,TAGLN3,NTRK2,PCDH9,PDGFRA,ENPP2,SERPINI1,PTCH1,ENOX1,RFX2,RGS4,RPS6KA2,SH3GL3,ASAP3,TNIK,ZCCHC24,ARHGAP26,ELOVL4,CEP68,RGL1,SYT11,SYT1,COBL,SSBP2,DNAJC12,SLC30A3,PLSCR4,DPF3" Drug 5496_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-11 2.91E-06 1.34E-08 1.52E-07 68 197 "SYN3,CNTNAP1,APC,FAM131A,ATP2A2,ALDH7A1,AZGP1,MTMR2,HAP1,RCBTB2,FOXN3,SULT4A1,PICK1,CNTN1,EDRF1,CTIF,BRINP1,MED12,HIPK3,PLXNC1,HSD17B14,LRRC17,RASGRP2,APC2,EZH1,FER,KIAA1109,CAMSAP1,ANKFY1,SORBS1,PRELID3A,GCNT2,COPS8,GPM6B,GPR22,NR3C1,KCNJ5,VWA5A,LSS,GIT1,LYRM9,NPR2,NRGN,P2RY1,LRP12,PPARA,PTPRO,RAD52,ATG16L1,PNMA8A,ZNF821,COA1,SOX2,HECW1,ZC4H2,ST5,INKA2,SYT5,ATP11A,MCF2L,SMG6,RPGRIP1L,PHF24,PIK3R5,TRPM2,EMSY,NT5M,KCNAB1" Drug 3639_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-11 2.91E-06 1.34E-08 1.52E-07 68 197 "ADORA1,SEMA6A,MARK4,ASTN1,CADM3,CFAP410,KALRN,CAMK2B,CAMK2G,USP2,CDH2,CPS1,CRMP1,NCOR2,AATK,SPOCK2,SRGAP3,EDN1,SGK2,ELAVL2,KCNMB2,KIAA1109,CAMKK2,GABRG2,GAD2,ADAM28,RND1,GNAO1,GNG3,GPM6A,GRIK1,KLF12,SYNPO,TJAP1,INPP5B,KCNH2,KIF5A,ADAM22,NELL2,NF1,NFYA,NUMA1,PNMA3,TNPO2,C19orf57,PTAFR,PTH1R,RGS12,SH3GL3,SLA,KDM4D,SHANK2,TSNAXIP1,SOX10,HECW1,IQSEC2,ZBTB43,TAC3,HIF3A,HEY2,TMOD1,TRO,UBE3A,VIPR2,LAT2,KCNK12,NT5M,SLC17A7" Drug 2186_UP Evoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.94E-11 2.91E-06 1.34E-08 1.52E-07 68 197 "NR0B1,PLA2G6,ANK3,LGR5,FGF17,KSR1,BMP7,C5,CAMK2A,NEURL1,GPR37L1,ASIC3,CHM,STOML1,TCEAL2,CREM,CSF1,SIPA1L1,PDE4DIP,SPOCK2,PARD6A,SPOCK3,ABCC9,OPTN,SORBS3,ELN,VPS13B,PRELID3A,GABRA2,MYOZ2,CSDC2,C1QL1,PCSK1N,GRK4,RASSF8,PTGDR2,KCND3,MOBP,CD200,MSI1,ADAM22,MYCN,NEUROD1,DUSP26,SLC25A23,MAPK7,WDR25,PEX5,GAL3ST4,FRMPD1,SLC1A7,SHANK2,SOX10,HECW1,ATP10B,VAMP1,ATP11A,TCF4,DOCK9,RALYL,SLC19A3,ARHGEF12,FLRT1,SEMA3B,SLC17A7,PLSCR4,PAK5,CAMK1G" Drug 4430_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.37E-11 3.12E-06 1.42E-08 1.61E-07 66 189 "ADD2,GRAMD1B,BEGAIN,SEMA7A,BCAS1,DDX3Y,SLC2A11,BACH1,BTRC,HAP1,RUNX1T1,CBS,LDB2,CLU,DNAJB5,CRY2,PLCH2,CTH,EDRF1,GIT2,DSCAM,DTNA,EDN1,SEMA3D,ABCA8,ATP8A1,OLFM1,CAP2,GAD2,ERAP1,GSTM5,SYNPO,KCNN2,LSS,MMP16,CD200,MYBPC1,NF1,NPY,NPTX2,OXTR,PALM,PDE4B,PDGFRA,PURG,PRKAR1B,PTAFR,PTCH1,MARCH1,RASGRF1,RGS12,RNASEL,KCNIP1,FOXRED2,SCN8A,HSPA4L,NTNG1,HKDC1,SLC11A1,RBM34,PDZD2,HECW1,NCDN,AJAP1,ZMYND8,PARP11" Drug 2904_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.37E-11 3.12E-06 1.42E-08 1.61E-07 66 189 "ABHD6,NDRG2,BIN1,APBB2,ARHGAP5,ST3GAL5,SGCE,HIP1R,MAP7,INA,CDO1,CLGN,CLCN4,RAB26,CREM,NCOR2,ABCG1,FEZ1,DOCK4,RIMS3,DNAJC6,MAGI2,DLG4,MAMLD1,SIDT2,FAM13A,MRNIP,ETV1,FGFR1,FHL1,GPR19,STON1,DIPK1A,KIF5C,MYO6,ZNF862,NCAM1,NEK1,PCDH9,TMOD2,SERPINI1,PLCD1,SLC25A23,PMP22,POU6F1,TMEM255A,FAM184A,TTLL7,MYH14,PRR5L,ASRGL1,ANKRD6,SLC1A3,SNCA,PALLD,TNIK,ELOVL4,RGL1,STXBP1,CAMSAP2,ZEB1,TPM1,CLIP2,SLC13A3,SH3GLB2,FZD3" Drug 5935_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.56E-11 3.21E-06 1.45E-08 1.65E-07 65 185 "ADD3,ADRB2,BAIAP3,CDK5R2,CACNB2,CDH18,CLGN,CLCN3,DNAJB5,PDE4DIP,SEC14L5,KIAA0319,SRGAP3,TMCC2,FRY,EFNA3,FAM13A,TUBB4A,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,TDRKH,PCLO,RNFT2,ITGA7,KIF5C,VWA5A,NAP1L3,PCDH9,ENPP2,SERPINI1,PIK3CD,RETREG1,PRPH,RADX,TTLL7,RPS6KA2,SMPD3,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,OGDHL,ZCCHC24,KIF21B,SOX15,ZHX3,PEG10,ARHGAP26,SPTB,RGL1,ACSBG1,SYT11,VAMP1,ZEB1,HEY1,RUNDC3B,DNAJC12,CLIP2,SLC17A7" Drug 1535_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.73E-11 3.30E-06 1.48E-08 1.68E-07 64 181 "ADD3,NME5,KIAA1324,PPP4R4,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,RASGRP2,STX2,TUBB4A,BAIAP2,DPYSL4,FYN,INPP5K,CYP46A1,RND1,RAB40B,STON1,KIF5C,MXI1,PCDH9,PDE4A,SERPINI1,PIK3CD,PKIA,PRPH,RAB3A,RPS6KA2,SGK1,SH3GL3,PPM1E,ASAP3,SYBU,ZNF365,WDR47,FAM214B,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,ZEB1,TRIM2,HEY1,BEX4,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 1471_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.73E-11 3.30E-06 1.48E-08 1.68E-07 64 181 "ALCAM,SRPX,MARK4,BMP7,ST3GAL5,RAB29,BAIAP3,HAP1,CAMK2B,CLGN,KIAA0513,ARMCX2,DNAJC6,EFNA3,EFNB3,MBNL2,EXTL2,F3,HPCAL4,IQCG,DPYSL4,FYN,CYP46A1,GLS,RAB40B,STON1,KIF5C,MXI1,ZNF862,NEK1,PCDH9,PDE4A,SERPINE2,SERPINI1,PIK3CD,RETREG1,PLCD1,GRAMD1C,PRPH,RAB3A,SH3BGR,SH3GL3,ASAP3,SYBU,ZNF365,WDR47,FAM214B,LIMCH1,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,UBE2H,DNAJC12,SLC30A3,SLC17A7" Drug CID000004497 nimodipine Stitch 6.77E-11 3.32E-06 1.48E-08 1.69E-07 55 145 "ACHE,BRAP,APLP1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CACNA2D2,ABCG2,APPL1,EDN1,EDN3,CACNG7,CACNG3,CACNG2,PTK2B,ZMYND10,ATP2C1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,RAPGEF4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PENK,CDK14,ABCB1,PKD1,QDPR,RYR1,RYR3,CASC3,TPCN2,TRH" Drug 6493_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.87E-11 3.37E-06 1.50E-08 1.70E-07 63 177 "ADD3,NME5,ARHGDIG,MARK4,ST3GAL5,CACNA1G,BAIAP3,CLGN,DOCK4,KIAA0513,ARMCX2,DNAJC6,EFNA3,EFNB3,FAM13A,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RUNDC3A,RND1,GLS,RAB40B,STON1,PADI2,DIPK1A,KCNN2,KIF5C,VWA5A,MXI1,NAP1L3,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,GAL3ST4,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,SYBU,WDR47,FAM214B,PKNOX2,CCDC88A,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,ZEB1,TRIM2,HEY1,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 981_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.99E-11 3.43E-06 1.52E-08 1.73E-07 62 173 "ADD3,ALAD,ARNTL,MARK4,ST3GAL5,SCAPER,BAIAP3,BTRC,CBFA2T2,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,EFNB3,MBNL2,TUBB4A,TAOK3,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,RNFT2,PADI2,ACOT7,KIF5C,MITF,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,PKIA,PRPH,LRRC49,RAB3A,SH3BGR,SH3GL3,PPM1E,WDR47,SLC6A8,SLC22A4,ZCCHC24,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,NPL,RUNDC3B,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 3671_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.67E-11 3.76E-06 1.63E-08 1.86E-07 68 198 "ADD2,ANK2,PPFIA4,PDE8B,ATP1A2,SLC4A4,DLGAP2,ARHGAP22,STOML1,AKAP6,IFFO1,AKAP12,GREB1,RIMS3,PHYHIP,DAPK3,HEPH,MFAP3L,DYRK1A,EDN1,SORBS3,ZNF589,KIAA1109,CAMSAP1,SIGLEC8,NEU3,ALDH1L1,GLS,GNAL,ADAMTS8,PADI2,PTGDR2,C2orf72,INPP5B,KCNJ9,MOBP,MYO7A,NF1,PDGFRA,PFKFB2,CAMKV,MTRF1L,STRN3,PPP2R2B,C1orf54,ZMAT4,RFX2,RGS12,SUGCT,EMID1,KCNIP1,SLA,SLC1A7,SLCO1A2,SCN3B,SOX2,SPTB,VAMP1,TCF7,TNS1,SEZ6L,TRIO,VIPR2,SPHK2,STMN4,KCNAB1,MVB12B,AP3B2" Drug 5387_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.67E-11 3.76E-06 1.63E-08 1.86E-07 68 198 "ASIC1,MRTFA,OGT,APOC1,PLA2G4C,ATM,N4BP2L1,KSR1,BAIAP3,CA4,CAMK2B,CBFA2T2,CACNA2D2,ADGRG1,DNAJB5,SULT4A1,AKAP7,CPS1,AATK,CSF1,TOX,TMCC2,ATN1,EFNB3,EGR3,ELN,C3orf18,KIAA1109,FHL1,FOXG1,SORBS1,TRAF3IP2,GATM,GLYR1,CACFD1,GRM1,KCNN1,LMO1,MSR1,MYO7A,NEUROD1,NOS1,PC,PLCD1,TNPO2,POLG,MAPK7,PTN,CCDC40,TTLL7,RPS6KA2,RASA3,FRMPD1,FBXO11,SLC8A1,SMARCD3,PDZD2,DOK5,BEX1,ZEB1,ZNF34,TIMP4,TMOD1,SYNC,WNK1,NT5M,ADAMTSL3,SENP7" Drug 4093_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.67E-11 3.76E-06 1.63E-08 1.86E-07 68 198 "ADD2,AP2A2,ADGRF5,AQP4,ASTN1,SYNJ1,ST3GAL5,SYNJ2,IL33,CACNA1A,PLEKHB1,ARHGAP22,RAB28,ZFYVE9,DNAJB5,RAB26,AKAP7,ENTPD4,AATK,CSF1,ARHGAP32,DAPK3,CTIF,BRINP1,MFAP3L,RUSC2,SMG7,EXOG,EDN1,EFNA3,PLEKHO1,MTSS1L,ZNF549,ETV1,FGFR1,DLL3,GAB1,ZNF44,TRAF3IP2,GLYR1,GNAL,GPR19,GRM1,SYNPO,HNMT,KIF5C,MOBP,MPP2,SERPINI1,SPATA6,PPARA,PRPH,SAMD9,RAP1GAP,GSTCD,RPS20,SELL,DZIP1,ZNF415,SPTAN1,MCF2L,TRIM2,TK2,TRIO,HIRA,WIPF1,XRCC4,EMSY" Drug 3053_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.67E-11 3.76E-06 1.63E-08 1.86E-07 68 198 "ABAT,NDRG2,MTUS1,SYT13,CDC42BPA,ANK3,DDO,CDC14B,PLA2G4C,ALDH4A1,NRP2,THSD7A,USP2,SYNGR3,SEPT7,REPS2,CDO1,NDST3,LHX2,SULT4A1,CNR1,CNTFR,COL9A3,CSF1,CHD5,PDE4DIP,MAGI2,TRAPPC9,ABCC9,HEYL,CALCRL,EPHB1,STX2,PTK2B,HPCAL4,SIGLEC8,MYOZ2,KCNMB4,GPR19,PTGDR2,SHISAL1,IL6ST,KCNF1,KCNJ5,NEUROD2,NRCAM,PCSK2,PLEC,FSD1,MAPK7,PTHLH,PTPRN2,ZMAT4,RGS12,ZFHX4,SLC1A2,EPN2,PKNOX2,TNIK,PEG10,TBCEL,WSCD1,PCDHGB6,ATP13A2,TK2,TMOD1,TRIO,FZD3" Drug 5511_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.80E-11 4.31E-06 1.87E-08 2.12E-07 64 182 "ABHD6,ADD3,NME5,CDC14B,ST3GAL5,GYG2,CDH18,CLGN,AKAP12,PDE4DIP,RIMS3,ARMCX2,DNAJC6,TSPAN5,EFNA3,EFNB3,FAM13A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,ICA1,KIF5C,VWA5A,MITF,MXI1,NAP1L3,SERPINI1,PIK3CD,SLC25A23,PRPH,RAB3A,GAL3ST4,ROBO1,RPS6KA2,SH3GL3,SYBU,SMTN,WDR47,FAM214B,PKNOX2,CCDC88A,TNIK,ZCCHC24,KIF21B,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,ZKSCAN5,DNAJC12,SLC30A3,EVI5" Drug 5231_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.21E-11 4.51E-06 1.95E-08 2.21E-07 62 174 "ADD3,NME5,MARK4,ST3GAL5,BAIAP3,SLC16A4,CDH18,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,EFNA3,EFNB3,FAM13A,MBNL2,TUBB4A,BAIAP2,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,GRB10,KIF3A,KIF5C,VWA5A,MXI1,NAP1L3,NEK1,PCDH9,ENPP2,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,RADX,SH3GL3,WDR47,FAM214B,PKNOX2,ZCCHC24,SPTAN1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,HEY1,NPL,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7,ITM2C,PLSCR4" Drug CID000448294 AC1L9LT0 Stitch 9.73E-11 4.77E-06 2.03E-08 2.30E-07 49 123 "ANK1,ANK2,ANK3,APC,ALS2,CASK,RIPK1,MPDZ,BTRC,LARGE1,MAGI1,DLGAP1,TJP2,PICK1,ARHGEF4,PARD6A,DLG2,DLG3,DLG4,EPB41,APC2,CACNG2,MPP6,SDCBP2,NKX6-2,GRIA1,GRIA2,GRIN2C,GRIN2D,KCNA4,KCNJ16,LMO2,CTNNA3,NFE2L2,PCSK2,PTPN13,MAPK12,SEC14L1,MAGI3,SLC15A2,SLC22A4,FBXW11,ARHGEF12,CRB1,TJP1,NEIL2,UBC,CADM1,UBE3A" Drug 4115_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "SYN3,ACTN2,ALCAM,LTBP4,ALK,SYT13,ANK1,AQP4,ASPH,SYNJ1,SYNJ2,CACNA1G,CBFA2T2,CRLF1,SLIT2,CLCN4,FADS2,WHRN,PLCH2,VCAN,DAPK1,ATN1,MRNIP,ZNF391,SPEG,KIAA1109,DCTN2,GABRA2,SIGLEC8,RND1,ICA1,KCNN1,VWA5A,MMP17,ADAM22,MX1,MYO7A,OMG,PDE4D,GPR85,RETREG1,PMP2,POU3F2,PPP5C,PRKAR1B,PRKCB,CNTLN,RAB3A,RAB3IL1,CCDC40,RGS10,RNASE1,RNASEL,RYR1,PPP1R9A,DOCK10,ARHGEF40,SLC11A1,ARHGAP26,AJAP1,EXOC7,SZT2,LILRA4,RUNDC3B,UGT8,MKRN3,SLC17A7,SSPN" Drug 3557_UP Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "NDRG2,AMPH,APBA2,ALDH4A1,ATP1A3,N4BP2L1,BACH1,ARHGAP33,GPR37L1,CHRNA4,ATRNL1,PDE4DIP,CNTNAP2,SPOCK2,CTIF,EDNRB,CNNM1,EFNA3,TENM1,C3orf18,KCNMB2,ERCC2,FHL1,SEMA4D,FLNC,CAMKK2,GPR153,FYB1,DKK3,GAD1,RND1,GPER1,GPR37,ELOVL5,MAOB,MAP2,MID1,GIT1,MYO7A,NF1,NOVA2,NPPA,NTRK2,NTRK3,PC,PMP2,LRRN3,RELN,PLPPR1,FAM120C,C1orf54,KHDRBS2,RGS12,RLBP1,EMID1,RTN1,SEMA6D,FAM214B,SLN,UNC5B,ATP10B,SYT11,WSCD1,SZT2,TNS1,PIK3R5,CHST5,SSPN" Drug 4777_UP Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "RALGAPA1,AP2A2,BEGAIN,AMPD3,PPP4R4,MARK4,CADM3,CFLAR,BTRC,CACNG1,SCARB1,ARHGEF2,ADGRG1,CHN2,CLCN4,FADS2,CNTN1,COL9A3,CRMP1,GIT2,DBN1,DMPK,FRY,EFNA3,DENND4A,SPEG,NRN1,ACSL4,FER,BAIAP2,FHL1,SORBS1,GPR153,GNAS,GPER1,ADAMTS13,GRIN1,GRM7,AP4S1,IL6ST,KCNH2,KCNJ5,VWA5A,CD200,ADAM22,NF1,OPCML,PDE3B,SERPINI1,CDIP1,FBXW7,TCP11L1,ASAP3,SLA,SLC2A5,SLC11A1,SMARCD3,SNCA,KDM4B,WDTC1,SYT11,TCF4,TRIM2,SLC19A3,CRTC1,TGFBR3,CHST5,PARP11" Drug 5048_UP Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "ASIC1,AK2,MRTFA,APAF1,APC,GAS7,APOC1,CDK10,SEMA4G,PPP4R4,MADD,CDK13,BRINP2,BMP7,ASIC3,RAB26,IQCK,DBT,SRGAP3,ELN,COQ7,SPEG,PTK2B,FGF1,FGFR1,FAM49B,GAB1,SYT17,GNG4,ATF7,GPER1,GRIK5,GRM8,KLF12,KCNN1,MATN3,KITLG,NEUROD1,NF1,OCRL,PDE4B,RETREG1,TNPO2,PPP5C,GRAMD1C,PTPRH,PID1,RAD52,SCN3A,IL17RB,DOCK10,PKNOX2,ZHX3,IZUMO4,ARHGAP26,ATP10B,ACSBG1,PLCB1,COBL,SZT2,DOCK9,DNAH7,SLC44A1,TMOD1,MKRN3,WNK1,KCNAB1,MVB12B" Drug 5772_UP Oxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "RALGAPA1,SYN3,ADORA2A,NME5,BEGAIN,EPB41L5,ADGRB3,RGS9,CACNA1D,CALB2,MTMR7,CD86,PLAA,CLCN4,HOMER3,COL9A2,ABCG1,RIMS2,RIMS3,DGKG,RABGAP1L,ARNT2,ECM2,DYRK1A,FRY,ING4,NCALD,APC2,EZH1,FGF1,FGF12,OGA,MYOZ2,GNAO1,GPR17,GRK4,NXPH3,ATXN2L,KCND3,KIFC3,LMO2,MAN2A2,MSR1,MYCN,NRCAM,OPRL1,PTCH1,PTPRB,RASA3,PPM1E,FRMPD1,HKDC1,DZIP1,SLC8A1,SLC11A1,SLC14A1,KIF13A,SP4,SPP1,SPTAN1,SEMA4A,DICER1,THBS4,SLC44A1,TLR4,TPM3,RPRM,ZIC3" Drug 5731_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.87E-11 4.84E-06 2.03E-08 2.30E-07 68 199 "KLRC4,SPARCL1,APBB1,APBB2,APC,NRP2,ST3GAL5,BTK,GYG2,SLC16A4,SCARB1,TMEM59L,HOMER3,ABCG1,CSF1R,PHF14,CX3CR1,PYGO1,RABGAP1L,HS3ST2,HIPK3,FGF12,DCTN2,GABRA2,SIGLEC8,SYT17,ALDH1L1,SRCAP,GFER,GPM6A,GRIK5,SOX21,HSD17B1,HTR2A,ITGA7,KCND3,KCNJ4,KCNMA1,LMO1,OPCML,PCSK2,PDE2A,PRKAR1B,PTAFR,PLPPR1,CCDC40,RFX2,PRR5L,ASIC4,SELL,SLC1A7,ARHGEF40,WDTC1,IZUMO4,SPTAN1,SYN2,MCF2L,TCF4,PCDHGA10,FAM189A1,TNS1,TMPRSS5,TUBB1,CADM1,RPRM,ZIC3,KCNAB1,FAM13C" Drug 3034_UP Capsaicin [404-86-4]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.03E-10 5.05E-06 2.09E-08 2.37E-07 67 195 "ABHD6,SEMA6A,ANK2,APBA2,DDO,PPP4R4,ALDH4A1,RUNX1T1,USP2,REPS2,CHRNA4,NRXN2,CLTB,ABCG2,WHRN,HAPLN1,SUSD5,ZNF337,BRINP1,DCC,ARNT2,HIPK3,HEYL,ELAVL4,EPB41,CEND1,TUBB4A,DLC1,AFF2,B3GAT1,TBR1,FYB1,GABRA3,GAP43,MSTN,PCDH17,RUNDC3A,ZNF276,GNAO1,GRM1,GUCY1A1,HLF,SYNPO,SCIN,KCNC1,KCNF1,KCNJ3,MAG,OPCML,PDGFRA,FSD1,POU6F1,PPP1R1A,BCAS3,PTPRB,MYH14,FERMT1,ASAP3,SLCO1A2,ARHGAP26,PHF24,CRTC1,AHCYL2,ATP13A2,TRPC1,VAV2,HRASLS" Drug 3201_DN Lidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-10 5.05E-06 2.09E-08 2.37E-07 67 195 "SEMA6A,CDC42BPA,ALDH4A1,SLC4A4,ATP2A2,ATP6V0A1,KIF1A,CFAP410,USP2,CDH10,CACNA2D2,PLEKHB1,TAOK2,QKI,NECTIN3,SH2B1,ARHGEF4,PPP6R2,EDRF1,CYBB,CTIF,SPOCK3,KBTBD11,ERCC2,DENND4A,APC2,FGFR1,ZNF44,GABRG2,ERAP1,COPS8,LPAR4,GRB10,NR3C1,RASSF8,IL6R,INPP5B,KCNH2,MATK,GIT1,NNAT,CAMKV,RETREG1,POLG,RELN,PTPRO,ZSCAN2,RGS12,CARF,NEK11,EMID1,WLS,FOXRED2,FNDC3A,ANKRD6,WDTC1,EMC1,ACSBG1,KAZN,NSD1,THRA,TMOD1,TRPC1,VIPR2,HPS4,UBE3B,SMIM8" Drug 5277_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.03E-10 5.05E-06 2.09E-08 2.37E-07 67 195 "ABHD6,NME5,AK2,SRPX,LTBP4,APC,GAS7,PDE8B,GYG2,BTRC,KYAT1,SYNGR3,ARHGEF2,FOXN3,LHX2,HOMER3,CNTNAP2,GREB1,ARHGEF4,NOS1AP,RASSF2,EXOG,EDNRA,EGFR,ING4,HSD17B14,DMTN,FGF12,GPR153,INPP5K,GPR19,PCLO,ICA1,IL6ST,KIF5A,LMO2,MPP2,ZNF862,GPR85,PRODH,RAB3IL1,RAD52,RALGDS,GTDC1,RGS3,RGS10,RGS12,ARHGEF10L,ZFHX4,PPP1R9A,ANKRD6,SLC6A8,SLC9A5,MAPKBP1,WDTC1,ZCCHC24,TROVE2,ARC,MCF2L,RPGRIP1L,PLPPR2,VAV1,ZNF23,REEP1,GDPD5,MPPE1,EPM2A" Drug ctd:C005556 propionaldehyde CTD 1.04E-10 5.09E-06 2.10E-08 2.38E-07 414 1982 "VWA5B2,ABAT,FAM43B,PLEKHG5,ELFN2,GALNT16,DSCAML1,ADORA2A,UNC5A,RNF150,ADRB2,SLC44A5,ZNF608,KLHL13,AGT,NR0B1,KIAA1324,OSBPL6,SRPX,CARNS1,MARCH4,GOLGA7B,PDZD4,AMPD3,AMPH,LRFN1,LRCH2,PI16,CCDC146,PPFIA4,CNIH2,DDO,SHROOM2,CDK10,SFMBT2,PPP4R4,PDXK,IGDCC4,ZFYVE28,ARRB1,LINC00173,ASGR1,MARCH3,STK33,DACT3,PTCH2,TMEM108,ALDH4A1,ATP1A2,RNF182,KIF1A,TTC9B,ADGRB1,BARD1,RGS9,BLM,GPR146,BMP7,ST3GAL5,CACNA1I,CACNA1G,BAIAP3,CA4,CACNA1B,DIRAS1,CAPN3,PRC1,CCK,SLC5A11,INA,DCLK1,EVI5L,TIGD7,CRLF1,CACNA2D2,GPR37L1,PLEKHB1,MS4A7,ARHGAP22,KIAA1549L,CLCN4,NRXN2,NGEF,FAM189A2,RAB26,CCDC151,CABP1,GAL3ST1,MFSD4A,CP,CRYM,CSF1R,CSF2RA,FEZ1,CHD5,RIMS4,PDE4DIP,PPP1R16B,ARHGEF4,SLC45A1,CTNND2,DOCK4,PHF19,RASSF2,RIMS3,SPOCK2,AIF1L,CNIH3,KIAA0319,TMEM130,LYPD1,CCDC3,KIF19,DMD,NR1D2,EDN3,EEF1A2,RASGRP1,TMTC1,FRY,CACNG7,EFNB3,FAM13A,EBI3,MRO,AASS,ENO2,RASGRP2,SLC43A2,ZNF549,TMEM74,CEND1,ADGRV1,MRVI1,F5,REEP2,ZNF585B,EFEMP1,CEP78,GTF2IRD2,FGF13,TMEM164,HPCAL4,C1orf61,AGAP2,FOXM1,AFF2,FLYWCH1,EFCAB2,SORBS1,SMC2,PDLIM5,NSG1,TMEM151A,FYN,MEGF11,DKK3,GAD1,BRPF3,JPH4,DISC1,CPLX2,DNER,GBX2,ALDH1L1,SULT1C4,SESN1,GFRA1,KIRREL3,GJB1,GLDC,KCNMB4,GNAO1,PSRC1,STON1,CECR2,ATP2B1-AS1,C1QL4,PLPP7,GRIN2C,CIT,LINC00839,LINGO1,ADAMTS6,GUCY1B1,SLC2A6,TOX2,PADI2,NXPH3,FRMD5,SYNPO,HMX1,HPCA,CPT1C,CELF5,ATCAY,ICA1,BTBD17,IGFBP1,NKD1,IGSF1,ITGA7,ITIH2,KCNH2,KCNMA1,KCNN1,KCNN3,KIF5C,L1CAM,TTYH2,LAMA2,STMN1,INSYN2,LMO2,FGFBP3,GPR155,NAT8L,MAP6,MAPT,SYT9,CHST6,ADAM11,MKLN1,COL28A1,SESN3,MSRA,MYBPC1,LAYN,MYT1,FXYD7,NAP1L3,RCOR2,NEFM,NEFH,NEUROD2,NOS1,NOVA2,NPTX1,NPTX2,KSR2,OLR1,ZDHHC22,PAX6,PDE2A,PDGFRA,GPR173,ZDHHC8,DUSP26,SERPINE2,NALCN,CAMKV,ANLN,RETREG1,TMEM38A,KCTD15,ST8SIA5,JAKMIP1,PLIN1,PLXNB3,CDIP1,SDK2,NECAB2,ING3,SEPT4,PACSIN1,FA2H,SKOR1,MAPK4,GRAMD1C,SMIM10L2B,PRPH,GDPD1,SAMD9,SYTL2,LAMA1,PTPRN,PTX3,RAB3A,PID1,TMEM255A,C1orf54,SLC25A41,FAM184A,RAP1GAP,ENOX1,RASGRF2,RADX,SLC6A15,CRTAC1,RET,SUGCT,KLHDC8A,SNX22,EPHA10,ARMH4,ZNF671,RPS6KA2,PLPPR3,MEG3,SOX8,WLS,ZNF568,SCN4B,TNFRSF19,SMPD3,ELMOD1,ZFP2,TMEM200C,PEAR1,TRIM46,GALNT10,STUM,ARX,SHC4,HKDC1,FHOD3,ST3GAL3,ABLIM3,SLC1A2,ZNF365,LIMS2,SLC6A8,SLC8A2,YPEL4,SHANK2,SLC14A1,EFHD1,SLN,MAST1,OGDHL,SNCA,MBD5,SNRPN,PALLD,TNIK,NMNAT2,IDI2-AS1,UNC5B,TSPYL2,NFASC,C11orf87,THSD1,SSTR2,ELOVL4,STAC2,SULF2,SEPT3,SYT11,ADAMTS17,ARC,SYN2,COBL,ASTN2,KAZN,CAMTA1,UNC5D,WSCD1,NEU4,TCF7,PCDHGB1,PCDHB10,PCDHB6,OBSL1,PCDHA3,PCDHA1,VWCE,TF,DNAH7,CRB1,ITGB3BP,ENHO,TIAM1,NACC2,HEY1,ICAM5,TMPO,BEX4,TNR,PIK3R5,LILRA4,TPM1,NPL,LRRC24,TRO,FNDC5,ZNF709,VAV1,VGF,LMF1,LAT2,SLC13A3,CFAP52,NDRG4,CELF4,DPYSL5,SLC30A3,PMEPA1,CADM2,RGMA,LINC02210,PRDM8,SCG2,NAV3,HRASLS,DNAH10,TMEM63C,CASC15,ADAMTSL3,NLRP3,VANGL2,ADAMTS10,PIANP,PRRT4,JPH3" Drug CID000002520 verapamil Stitch 1.04E-10 5.12E-06 2.10E-08 2.39E-07 132 490 "ABCF1,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,ALAD,ABCD2,MYH7B,KCNAB2,APOC1,APOC2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,KRIT1,CACNA2D2,ASIC3,CHRM1,CHRNA4,CHRNB2,CLCN3,ABCG2,COL4A5,ABCG1,BOC,ABCC5,ABCC9,EDN1,EDN3,EDNRA,CACNG7,EGFR,KCNMB2,ABCA8,CACNG3,CACNG2,PTK2B,ATP2C1,GCNT2,MSTN,KCNMB4,MAP4K5,HPSE2,HTR2A,IGF1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,MYH3,MYH6,MYH7,MYO5A,MYO6,NODAL,NOS1,NPPA,KCNK10,ABCB1,PIK3C2A,PKD1,PRKCB,PRKCG,PKN2,PRKCZ,RNH1,MYH14,RYR1,RYR3,AP1AR,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,MYO18A,SLCO1A2,SLC22A4,SCN3B,SPP1,SST,APOM,TPCN2,LEFTY2,TRH,KCNE5,KCNT2,KCNAB1" Drug 4184_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.18E-10 5.78E-06 2.36E-08 2.69E-07 63 179 "ABAT,ADRB2,MTUS1,APAF1,EPB41L5,SHROOM2,CDC14B,ARNTL,MARCH3,NOL4,ST3GAL5,SYNGR3,PREPL,ABCG1,FEZ1,PDE4DIP,CTH,DNAJC6,PLPPR4,RGS17,PTK2B,TAOK3,TESK2,BAIAP2,DPYSL4,NBEA,PNMA2,FYN,PCDH17,RND1,STON1,GUCY1B1,BACH2,DIPK1A,KCNJ5,KIF5C,LIFR,VWA5A,TAGLN3,PCDH9,PDGFRA,SERPINI1,RETREG1,PRPH,PTCH1,PTN,ENOX1,RGS4,RPS6KA2,RPS20,SH3GL3,DOP1A,TNIK,THSD1,ELOVL4,CEP68,RGL1,SYT11,SYT1,COBL,TNS1,DNAJC12,SLC30A3" Drug CID000002551 carbachol Stitch 1.20E-10 5.88E-06 2.38E-08 2.71E-07 172 688 "ACHE,ACLY,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,AMH,MYH7B,APOC2,APP,SLC4A4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,BCHE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,CAMK2D,CCK,CCKBR,KRIT1,LRBA,CACNA2D2,CHRM1,CHRNA4,CHRNB2,MYL6B,CNR1,PLCXD3,MYEF2,DMPK,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,BSCL2,KCNMB2,ERBB4,RPS6KC1,CACNG3,CACNG2,PTK2B,ACTL6B,FOXM1,ATP2C1,B3GAT1,FYN,GALR1,INPP5K,GCNT2,KCNMB4,GNAL,GNAO1,GNAS,GNG3,PLCD4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,IRAK3,PTGDR2,HRH3,HNMT,MYLK2,KCNC1,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNMA1,KCNN1,KCNN3,MATK,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,NOS1,NPY,NPPA,NPR2,OGDH,P2RY1,PDE1A,PDE2A,PDE3A,PDE3B,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,PLCD1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,EPDR1,MAPK7,MAPK8,MAPK9,MAPK10,RGS3,RGS7,RIT2,RIC8B,RNH1,MYH14,RPS6KA2,RYR1,RYR3,MAPK12,MYO18A,SLA,SLC6A7,SNCA,ERC1,PEG10,SST,MLC1,PLCB1,TAC1,TAC3,TACR1,TBL1X,TPCN2,ACTR6,PIK3R5,TRH,TRPC1,TRPC3,TRPM2,VIPR2,PORCN,ZIC3,PRDM2,HPS4,PLD4" Drug 3428_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.21E-10 5.93E-06 2.38E-08 2.71E-07 62 175 "ADD3,NME5,SRPX,ARNTL,BMP7,ST3GAL5,CLGN,UBE2L6,CRYM,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,DPYSL4,FYN,CYP46A1,RND1,RAB40B,STON1,RNFT2,KIF5C,MITF,MPP2,MXI1,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,LRRC49,RAB3A,SH3GL3,PPM1E,WDR47,PKNOX2,ZCCHC24,KIF21B,SPTAN1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,REEP1,SLC17A7,ITM2C" Drug 909_UP HC toxin from Helminthosporium carbonum; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.21E-10 5.93E-06 2.38E-08 2.71E-07 62 175 "ADD3,ALCAM,PPFIA3,ARNTL,BMP7,ST3GAL5,BAIAP3,CLGN,UBE2L6,AKAP12,KIAA0513,ARMCX2,DNAJC6,TSPAN5,EFNA3,EFNB3,MBNL2,RASGRP2,TUBB4A,FHL1,DPYSL4,FYN,GLS,STON1,GPR37,RNFT2,KIF5C,MITF,MPP2,MXI1,NEK1,PDE4A,PIK3CD,PMP22,PKIA,PRPH,LRRC49,PTCH1,RAB3A,GSTCD,SH3BGR,SH3GL3,PPM1E,LIMCH1,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,HEY1,BEX4,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 4153_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.21E-10 5.93E-06 2.38E-08 2.71E-07 62 175 "ADRB2,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,CRYM,PDE4DIP,KIAA0513,ARMCX2,TSPAN5,EFNB3,FAM13A,RASGRP2,TUBB4A,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,C1QL1,RND1,STON1,KCNH2,KIF5C,MAP2,MEF2C,NAP1L3,PAH,PDE4A,ABCB1,SERPINI1,PIK3CD,PRPH,RAB3A,RADX,TTLL7,NUDT11,SH3GL3,ASAP3,ST6GAL1,WDR47,PKNOX2,CCDC88A,ZCCHC24,SOX15,NMNAT2,PEG10,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,HEY1,TNS1,RUNDC3B,DNAJC12,CLIP2,SLC30A3,SLC17A7,ITM2C" Drug 4995_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.27E-10 6.22E-06 2.47E-08 2.81E-07 68 200 "ADCY6,ADD2,BIN1,ANK3,CDC14B,PDE8B,MARK4,ALDH4A1,SCAPER,GYG2,SGCE,BAIAP3,LDLRAD4,KYAT1,CCKBR,FOXN3,CHN2,CHRNB2,CNTN1,CSF1,ARHGEF4,SV2A,DRD1,ATN1,DYRK1A,EDN1,SORBS3,LRRC23,DLC1,OLFM1,FGF13,FGFR1,FHL1,AGAP2,GAB1,PCDH17,GPR75,GLS,GNAS,GPM6B,GPER1,GRK4,ADAMTS13,ICA1,VWA5A,MID1,KCNK10,CAMKV,MAPK8,FAT4,ZNF493,KHDRBS2,TTLL7,SBF1,SH3BP2,WDTC1,INKA2,KIAA1107,CRTC1,HIF3A,TEX15,PARD3,TPM2,TRPC1,VAV2,ZFP37,SEMA3B,MVB12B" Drug 2633_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.27E-10 6.22E-06 2.47E-08 2.81E-07 68 200 "ASIC1,AP2A2,AGT,NME5,MRTFA,ANK1,APBA2,APLP1,APOC1,MARK4,SLC4A4,AZGP1,ADGRB1,CACNA1I,CA4,ARHGEF1,TAOK2,NRG2,CREB5,ARHGEF10,PDE4DIP,MFAP3L,DMPK,HS3ST2,HEYL,FRY,SIDT2,EIF4G2,ELAVL3,HSD17B14,PIPOX,TUBB4A,ZNF589,FGFR1,C1orf61,GAD1,CPLX2,C1QL1,RND1,RAB30,GPR75,TDRKH,STON1,GRM8,INPP5B,MAPT,KITLG,MSR1,NOS1,NOVA2,OMG,PENK,PIK3CD,C19orf57,GON4L,ATG16L1,SH3BP2,ZNF365,SMARCD3,SPTAN1,PSD3,TK2,VSNL1,ZFP37,ZNF154,ADAMTS9,SMIM8,TIGD6" Drug 4639_DN Felbinac [5728-52-9]; Down 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.27E-10 6.22E-06 2.47E-08 2.81E-07 68 200 "DDO,APOC1,CDC14B,SEMA4G,ASPH,ALDH4A1,STX16,KIF1A,SYNJ2,SCARB1,PLEKHB1,TAOK2,ABCG2,DNAJB5,SLC4A8,TCEAL2,CSF1R,SDC3,TBC1D5,BRINP1,MFAP3L,FCF1,MBNL2,IRAK4,ETV1,RRAGB,IQCG,AFF2,LYVE1,GLYR1,MSL3,GPR17,GRM8,INPP5B,LIG4,MAPT,NDUFA5,NOVA1,NUMA1,OPCML,PALM,PLCD1,PRKAB2,GRAMD1C,SAMD9,GON4L,BEND5,KHDRBS2,FOXRED2,SCN2B,ZNF821,FRMPD1,SLA,CCDC88A,BTBD7,SMARCD3,SS18,SYT1,ADGRL3,DOCK9,TK2,RIMBP2,TRIO,CADM1,NSD2,XRCC4,UPF3A,SCG2" Drug 5097_UP Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.33E-10 6.50E-06 2.53E-08 2.88E-07 67 196 "ASIC1,NDRG2,APC,ARHGDIG,BRINP2,CACNA2D2,FOXN3,CHN2,RAB33A,TCEAL2,ENTPD4,CHD5,VCAN,CTNND2,DCC,TOM1,DYRK1A,USH1C,EDNRA,SIDT2,AASS,FABP7,CORO2B,KIAA1109,EFCAB2,SORBS1,PDLIM5,ZNF44,DISC1,GPR17,LPAR4,GRIK5,GRM7,KIFC3,MMP16,MYO7A,NDUFA5,NF1,NOS1,NOVA1,PALM,PDE2A,PDE4D,PFKFB2,RETREG1,PPP5C,SNRK,PTPRB,FAM120C,RASGRF1,GAL3ST4,KCTD17,RXRA,ZNF821,FRMPD1,ASAP3,DZIP1,KANSL3,ZNF667,PDZRN3,SPTAN1,ZBTB43,CABIN1,TNS1,VIPR2,MVB12B,GAN" Drug 4419_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-10 6.50E-06 2.53E-08 2.88E-07 67 196 "SYN3,ASIC1,ACTN2,ADORA1,LTBP4,BEGAIN,AMH,KCNAB2,CDC14B,ARHGDIG,ASCL1,BTK,CACNA2D1,SLC16A4,CD86,CDO1,CLCN4,STOML1,SULT4A1,PCYT1B,VCAN,CTH,BRINP1,DBT,EFNB3,MBNL2,C3orf18,KIAA1109,OLFM1,TBR1,GABRA2,LYVE1,GLS,GPER1,SPACA9,JAK2,KCNJ5,KIFC3,MN1,MX1,MYT1,NPPA,NPR2,PFKFB2,PRKCB,PTPRB,ZNF493,RGS12,MYH14,SBF1,ZNF821,SLC1A2,SLC2A5,KANSL3,SLC11A1,SLN,COA1,SMARCD3,ATP10B,POPDC3,TACR1,HIF3A,HEY2,UCHL1,WIPF1,STMN4,ITM2C" Drug 3789_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.33E-10 6.50E-06 2.53E-08 2.88E-07 67 196 "LTBP4,AMH,CDC14B,CDK13,CADM3,ADGRB2,NRP2,MTMR3,CACNA1I,LDLRAD4,CACNA1D,CH25H,SYNGR3,ADGRG1,NTM,DLG4,ATN1,ELAVL4,ELN,CEND1,EZH1,FABP7,TUBB4A,FGFR3,ATP8A2,ALDH1L1,GFRA1,CSDC2,GLYR1,PRUNE2,ATF7,LILRA2,GRM1,GRM2,GRM7,GSTM5,HSD17B1,IGF1,KCNB1,VWA5A,SMAD1,MMP16,NF1,NPTX1,OPCML,P2RX7,CDK18,EPN1,NECAB2,PRKAR1B,PTPRD,STUM,SH3BP2,SLA,SLC11A1,SLCO1A2,KIF13A,FAIM2,ACSBG1,TACR1,TMOD1,CADM1,SLC13A3,SPHK2,ADAMTS9,SEMA3B,GJC2" Drug 3720_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.33E-10 6.50E-06 2.53E-08 2.88E-07 67 196 "ADCY2,PLA2G6,LTBP4,ALK,SEMA7A,PPP4R4,ZSCAN18,ZBTB10,RASL11B,NRP2,BMP7,BAIAP3,HAP1,SLC16A4,CDH8,CDO1,HAPLN1,NOS1AP,DGKG,MFAP3L,ECM2,EDNRA,IRAK4,KAT8,GAD2,ALDH1L1,PCDH17,GPD2,GPR17,HLF,SHISAL1,MATN3,NF1,NFYA,NPTX1,CLDN11,TREM2,PALM,PCDH9,CDK18,PDE4B,PFKFB2,PFKFB4,PLCB2,SPATA6,PROX1,PTN,FAM184A,ENOX1,RGS4,RNASE1,EMID1,AP1AR,SAFB,TRIM46,RASA3,SLC2A5,PKNOX2,NPAS3,ATP10B,INKA2,FAM168A,CADM1,FLRT2,SPHK2,REEP1,PARP6" Drug 3826_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.33E-10 6.50E-06 2.53E-08 2.88E-07 67 196 "TTYH1,ACTN2,NDRG2,SLC12A5,ADORA1,ALAD,LTBP4,APBB1,ASTN1,ADGRB2,CDO1,NRXN3,STOML1,RAB26,CREB5,ABCG1,CNTNAP2,CTNND2,TOX,DTNB,ELN,EPHB1,CEND1,EZH1,KAT8,BAIAP2,CAMSAP1,SEMA4D,AFF2,GAB1,ZNF44,POLL,GRM1,GRM2,KHK,KITLG,AFDN,MMP17,OMG,OPCML,PDE2A,GPR85,LRRN3,ZMAT4,RGS12,PNMA8A,EMID1,CSRNP3,PKNOX2,SLC11A1,ZNF667,SNAP25,ARHGAP26,ACSBG1,ATP11A,ADGRL3,TBCEL,DMXL2,DOCK9,OBSL1,PCDHA5,HIF3A,HEY2,TUBB1,LAT2,SLC17A7,KCNAB1" Drug 1634_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.38E-10 6.78E-06 2.62E-08 2.98E-07 66 192 "ASPHD1,ABHD6,NDRG2,SRPX,APAF1,APC,ST3GAL5,GYG2,RAB29,CLGN,CACNA2D2,DNAJB5,ABCG1,RASSF2,DBN1,ARMCX2,DNAJC6,LYPD1,EFNB3,SORBS3,ANKMY1,EXTL2,REEP2,ARMCX1,GPR153,FYN,GPM6B,TDRKH,GPR37,RASSF8,KIF5C,MPP2,MXI1,NPTX1,PALM,PDE4A,RETREG1,CNNM2,PTCH1,RAB3A,RNASEL,SBF1,SEC14L1,SH3GL3,ASAP3,FNDC3A,ZNF365,SLC2A5,ARHGEF40,SLC22A4,SNCA,WDTC1,ZCCHC24,STX1A,STXBP1,PLCB1,MTCL1,TRIM2,RBFOX2,TRPC1,VGF,MICAL1,NDRG4,REEP1,SLC30A3,PCBP4" Drug 4442_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.38E-10 6.78E-06 2.62E-08 2.98E-07 66 192 "GRAMD1B,BEGAIN,AQP4,KIF1A,KSR1,KALRN,HAP1,CAMK2B,CAMK2G,CBS,CACNA2D2,CLU,WHRN,CABP1,CRY2,OSBPL3,CTH,EDRF1,CTIF,GIT2,SV2B,RABGAP1L,EDN1,CELSR3,ST3GAL6,OLFM1,HPCAL4,FOXG1,SORBS1,GAB1,GFER,PCDH17,GLYR1,GRIN1,SYNPO,KCNH2,LIFR,SHC3,MMP16,NEUROD1,NPY,OXTR,PDE4B,PNMA3,POU6F1,CEP41,PTCH1,PTN,ACSS3,RET,RGS4,RNASEL,TCP11L1,HSPA4L,HKDC1,NLGN1,ZNF334,PDZD2,MYT1L,CRTC1,TEX15,TPM3,CHST5,TRO,OSBP2,REEP1" Drug 2208_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.44E-10 7.05E-06 2.71E-08 3.09E-07 65 188 "ABHD6,NDRG2,MTUS1,BIN1,CDC42BPA,APBB2,ST3GAL5,CFAP410,HIP1R,NEURL1,LHX2,AKAP6,CPS1,ABCG1,PDE4DIP,EDRF1,DOCK4,RIMS3,CTIF,DNAJC6,DCT,MAMLD1,VPS13B,ERBB2,ETV1,F5,ATP8A1,DLL3,GATM,STON1,PCLO,GRM1,ITGA7,KIF5A,KIF5C,NCAM1,NRCAM,PLCL1,PNMA3,PMP22,PPP2R2B,CRTAC1,WLS,SLC1A3,SNCA,PALLD,TNIK,ZSWIM8,PEG10,STXBP1,TCF4,RPGRIP1L,TEX15,ATP13A2,TMOD1,TNNT1,RBFOX2,TPM1,RUNDC3B,RPRM,BEST1,KLC2,TRIM9,STMN4,FZD3" Drug 4344_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.54E-10 7.54E-06 2.89E-08 3.29E-07 63 180 "DPF1,ABAT,ADRB2,APAF1,EPB41L5,BRINP2,NOL4,ST3GAL5,HIP1R,USP2,NRXN3,ABCG1,PDE4DIP,RIMS3,DNAJC6,PLPPR4,RGS17,F3,TAOK3,FGFR1,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,DIPK1A,KCNH2,KIF5C,MAP2,MAPT,MMP16,PALM,PCDH9,PDGFRA,SERPINI1,PIK3CD,RETREG1,GRAMD1C,PRPH,TMEM104,PTCH1,ENOX1,RGS4,MYH14,FBXW7,SH3GL3,ASAP3,KDM4B,TNIK,HECW1,ARHGAP26,NFASC,THSD1,ELOVL4,RGL1,SYT11,SYT1,RUNDC3B,DNAJC12,LAT2,TRIM9,EVI5,SLC17A7" Drug 5775_UP Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.71E-10 8.36E-06 3.14E-08 3.57E-07 67 197 "ADORA1,ADRA1D,BEGAIN,TRMT9B,APAF1,BCAS1,LGR5,ADAM23,BMP7,MYRF,CD86,CHN2,B4GALT6,SRGAP3,DPP6,DSCAM,DTNA,EDN3,ING4,ELAVL3,TNK2,COQ7,KCNMB2,FGF1,SEMA4D,OGA,GABRA2,SYT17,NEU3,SRCAP,GNG3,GPR17,STON1,MCHR1,GRIA4,SPACA9,SOX21,NXPH3,SHISAL1,KCND3,KCNH2,MDM4,ADAM22,NRCAM,PDE3B,EPN1,PNMA3,PPP2R2B,CEP41,MAPK3,PRODH,PID1,ENOX1,KCTD17,RNASE1,PRR5L,OGDHL,RIMS1,SOX2,DOK5,EMC1,CUX2,TEX15,SEZ6L,STMN4,PRDM10,HRASLS" Drug 5605_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.71E-10 8.36E-06 3.14E-08 3.57E-07 67 197 "DPF1,ASIC1,ADCY2,ADRA1D,AMPH,BIN1,ANK1,ATP2B3,KSR1,CA4,BRSK2,ADGRG1,CHN2,CNTN1,AATK,CSF1,SPOCK2,CTIF,DBN1,TOM1,SIDT2,EFNB3,RASGRP2,REEP2,FABP7,CACNG3,DLC1,FHL1,FYN,PCDH17,POLL,GRIN2C,GRM7,KLF12,KCNB1,VWA5A,MAP2,MGAT3,NCAM1,NOVA2,NUMA1,PFKFB2,CDK14,SERPINI1,MAPK7,KHDRBS2,MYH14,TCP11L1,EMID1,KCNIP1,LRRTM4,ZNF821,MRAS,SLC11A1,ZNF334,SOX10,SPTB,SYP,WSCD1,OBSL1,CRB1,DAAM2,LILRA4,VGF,SLC30A3,KCNAB1,FAM13C" Drug 6653_UP Bezafibrate [41859-67-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.71E-10 8.36E-06 3.14E-08 3.57E-07 67 197 "ASPHD1,ASIC1,ADD2,FAM135A,APBB2,ASCL1,CFLAR,FUBP1,BAIAP3,CA4,CACNA1A,SCARB1,NCOR2,PDE4DIP,CNTNAP2,AK5,DTNB,DUSP9,USH1C,SNX29,SEMA3D,EFNB3,ING4,TNK2,IGSF6,ETV1,F5,REEP2,OLFM1,FLT1,AFF2,OGA,FYB1,GCK,SRCAP,STMN2,ITGA7,KCNB1,KCNJ5,MAP2,CD200,ADAM22,NELL2,OGG1,PALM,GPR85,PFKFB2,DUSP26,RETREG1,NLE1,TMEM231,CCDC40,RGR,KIRREL1,FBXW7,SCN2A,SCN2B,FRMPD1,SNCA,PHLDB1,SYT5,HIF3A,R3HDM1,PARD3,PRDM2,KCNAB1,DPF3" Drug 5252_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.71E-10 8.36E-06 3.14E-08 3.57E-07 67 197 "ASIC1,MARK4,ATM,CADM3,ADAM23,MTMR3,CAMK2B,CHRNB2,AKAP5,CREM,SDC3,ARHGEF4,DAPK1,CTIF,DTNA,HEYL,EFNB3,EGR3,MTSS1L,F5,ZIC4,ATP8A1,OLFM1,CAMSAP1,SCARA3,FUT9,GABRA2,GAD2,DISC1,SRCAP,POLL,GNAO1,PRUNE2,GRB10,GRIK1,GRM1,GSTM5,KLF12,SYNPO,KCNN1,VWA5A,MID1,MOBP,ADAM22,MX1,SERPINI1,PLTP,PTAFR,RIPOR1,C1orf54,NLGN1,SLC1A7,PKNOX2,ZNF415,KIF21B,ZHX3,ZSWIM8,ERC1,ZNF423,SPTB,ZBTB43,TSPYL2,INKA2,SYT11,DMXL2,UGT8,LAT2" Drug 6642_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.71E-10 8.36E-06 3.14E-08 3.57E-07 67 197 "NDRG2,ADORA3,APBB2,CDC14B,CDK10,KIF1A,BMP7,LARGE1,DLGAP1,CHRNA4,IFFO1,TCEAL2,NCOR2,CSF1,RGS6,EDRF1,RIMS3,ARNT2,DMPK,DYRK1A,EFNB3,MRNIP,EFS,OLFM1,AFF2,ERGIC3,NSG1,GAP43,NEU3,RUNDC3A,TOX3,POLL,GNAO1,SPACA9,CELF3,VSIG4,HNF4G,KCND3,KCNJ5,PACRG,AFDN,MOBP,NCAM1,ENPP2,RETREG1,PPP1R1A,LRRN3,PKN2,MAPK8,ZSCAN2,ACSS3,RASGRF1,ZFP2,TRIM46,SLA,SNCA,COLGALT2,LILRA4,TRPC1,TMPRSS5,CADM1,VIPR2,SLC26A10,REEP1,SLC30A4,NT5M,DNALI1" Drug 4464_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-10 9.11E-06 3.41E-08 3.88E-07 65 189 "ASIC1,ACTN2,APBB1,APC,ARRB1,ADGRB2,ST3GAL5,GYG2,CFAP410,SYNGR3,CRLF1,CHN2,RAB33A,DNAJB5,WHRN,AKAP5,NCOR2,ABCG1,VCAN,PDE4DIP,EDRF1,FAM131B,RIMS3,MAGI2,EDN1,LRRC23,REEP2,TUBB4A,SCARA3,FYN,C1QL1,GLI2,TDRKH,STON1,GPR37,ITGA7,KCNH2,KIF5C,LIFR,OXTR,PALM,PDGFRA,PIK3R1,GRAMD1C,PRPH,PTCH1,RGS4,SH3GL3,FRMPD1,ASAP3,ARHGEF40,ELOVL4,ARC,SYT1,COBL,KLHL4,TCF4,SZT2,OBSL1,TGFBR3,THRA,TNS1,CDK20,NDRG4,ZNF225" Drug 5987_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.00E-10 9.81E-06 3.66E-08 4.17E-07 63 181 "DPF1,ADD3,NME5,MARK4,BMP7,ST3GAL5,BAIAP3,CACNB4,USP2,CDH18,CLGN,DNAJB5,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNA3,EFNB3,VPS13B,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,GLS,RAB40B,STON1,PCLO,KIF5C,VWA5A,MXI1,NAP1L3,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,PPP2R2B,GRAMD1C,PRPH,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,ZCCHC24,KIF21B,TSNAXIP1,THSD1,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,RUNDC3B,DNAJC12,GDPD5,SLC17A7,ITM2C" Drug CID000005514 T2755 Stitch 2.05E-10 1.00E-05 3.73E-08 4.24E-07 34 71 "ABAT,ASIC1,CA4,CA12,CACNA2D1,ASIC3,SLC32A1,GABRA1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KCNH2,NPY,PPARA,PTCH1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,CA14" Drug 3462_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.07E-10 1.01E-05 3.74E-08 4.26E-07 62 177 "ADD3,NME5,ALCAM,ST3GAL5,BAIAP3,CLGN,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,RNFT2,DIPK1A,KIF5C,MITF,ZNF862,NEK1,PCDH9,TMOD2,SERPINE2,SERPINI1,PIK3CD,PMP22,PRPH,RAB3A,ROBO1,RPS6KA2,SH3BGR,SH3GL3,PPM1E,ASAP3,WDR47,FAM214B,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,ZNF45,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 4632_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.17E-10 1.07E-05 3.74E-08 4.26E-07 60 169 "ABAT,ADCY6,ADRB2,MTUS1,NME5,ARNTL,ST3GAL5,FOXN3,WHRN,ABCG1,PDE4DIP,CTH,DNAJC6,C2CD2L,PLPPR4,EFNA3,RGS17,TAOK3,TESK2,FGFR1,BAIAP2,SORBS1,FYN,RND1,GLS,STON1,GUCY1B1,BACH2,KIF5C,LIFR,MEF2C,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINI1,RETREG1,PMP2,PRPH,PTCH1,RAB3A,ENOX1,RGS4,RTN1,FAM102A,SH3GL3,KDM4B,TNIK,BEX1,ARHGAP26,THSD1,ELOVL4,RGL1,PHLDB1,SYT11,SYT1,COBL,SSBP2,DNAJC12,PLSCR4" Drug 4464_DN 2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "RALGAPA1,MRTFA,CDC42BPA,ANK3,APAF1,PPP4R4,ASPH,ATP1A3,SCAPER,CACNA1I,CACNB2,CHRNB2,SLC22A6,SLC24A2,CSF1,MICAL2,EDRF1,MFAP3L,DMPK,EGFR,ING4,MRNIP,FGF12,HPCAL4,PDLIM5,GAB1,HBS1L,NEU3,GNG4,SPACA9,GRM1,PADI2,ARHGAP19,ATXN2L,KCNMA1,KCNQ3,VWA5A,KITLG,NF1,NFIX,CNOT4,NRCAM,PDE4D,PENK,PLCB2,POU3F2,LRRN3,PPP5C,PRKAR1B,PTPRB,TMEM231,KCTD17,MRAS,BCAN,SLA,PPP4R3A,SMARCD3,UNC5B,VAMP1,TBCEL,TRPC1,ZNF24,NT5M,EVI5,KAT6A,PHTF2,GAN" Drug 4346_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ALCAM,SEMA7A,CNTNAP1,GAS7,N4BP2L1,KALRN,CDH8,COL9A3,ARHGEF10,SRGAP3,ATN1,DUSP9,ELAVL3,EFS,SORBS1,CHL1,GABRG2,GAP43,CPLX2,SRCAP,GFER,ATF7,GPER1,TPPP,GRM2,GRM3,CELF3,IRAK3,KCND3,LMO1,MOBP,CD200,SLCO1C1,NOVA2,OPCML,KCNK10,PFKFB2,PURG,CEP41,MASP1,RELN,VPS13C,PTPRB,RASGRF1,RGS12,SLC30A10,SH3BP2,BTBD7,HECW1,ZC3H13,SPART,ZC4H2,POPDC3,TBCEL,SYNE1,SLC35G2,DNAH7,TNS1,VIPR2,WIPF1,LAT2,ZNF154,SLC30A3,EMSY,SLC17A7,PLSCR4,FAM13C" Drug 3196_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ADORA1,KIAA1324,ALCAM,APAF1,APP,ARHGDIG,ASTN1,DDX3Y,ATP1A2,SYNJ2,HAP1,ARHGAP33,CHN2,B4GALT6,EPS15L1,NMT2,IFFO1,MICAL2,IPCEF1,VCAN,PDE4DIP,RIMS3,MFAP3L,DUSP9,USH1C,FEM1B,ETV1,F5,REEP2,FOXG1,PDLIM5,FYB1,PCDH17,RND1,GLYR1,GNAO1,GPM6A,GPM6B,GRIN1,GRIN2D,GRM3,GSTM5,JAK2,KCNJ5,VWA5A,LSS,MAPT,AFDN,ADAM22,MSR1,SLCO1C1,CLDN11,PPP5C,RPS6KA2,SLC4A3,FAM214B,SHANK2,SLCO1A2,ZNF423,PLCB1,EXOC7,ADGRL3,SLC35G2,WIPF1,XRCC4,ZIC3,SLC30A4" Drug 6627_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ADCY2,ALK,TRMT9B,KCNAB2,CCDC181,ATP1A2,ATP1A3,CADM3,ADAM23,GYG2,BAIAP3,NMT2,CNTFR,CSF1,PDE4DIP,PHYHIP,SMG7,DTNA,DYRK1A,EDIL3,EDNRA,AASS,MTSS1L,EZH1,FGF1,FGFR1,FLT1,B3GAT1,GALC,ERAP1,ZNF276,GLI2,GNAL,GNAO1,LPAR4,GPER1,GRIK2,SPACA9,IRAK3,ELOVL5,KCNB1,KCND3,KCNN1,VWA5A,MAPT,TM6SF1,NF1,NNAT,NOVA1,PIK3R1,PLXNB1,PPP2R2B,PROX1,RAB3IL1,EMID1,SEMA6D,SCN2B,FRMPD1,ASAP3,NTNG1,NACAD,TACR1,SLC44A1,TPM1,RUNDC3B,VIPR2,JPH3" Drug 4253_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "TTYH1,SEMA6A,LTBP4,SEMA7A,APBB1,AQP4,PPP4R4,ASCL1,ZSCAN18,N4BP2L1,BACH1,SYNJ1,CDK5R2,CFAP410,CACNG1,CBS,FOXN3,ARHGAP22,AATK,CNTNAP2,CTNND2,CTIF,MAGI2,DYRK1A,EFNA3,TENM1,ELAVL3,COQ7,EPHB1,CAMSAP1,DCTN2,FYB1,NEU3,KLF12,IGFBP1,IL6ST,KCNJ3,KIT,MYH6,NCAM1,SLCO1C1,NPTX1,NRCAM,NTRK3,PCDH9,PCSK2,PHKG1,FXYD1,MAPK3,MAPK8,PTHLH,RGS10,SELL,SH3BP2,SPP1,SPTB,DDN,ARHGEF9,CRTC1,AP4E1,SEZ6L,TUBB1,KCNK12,SLC17A7,HRASLS,KAT6A,DPF3" Drug 6698_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ADD2,ADGRF5,MRTFA,PPFIA4,APBB2,APC,BCAS1,ADAM23,BMPR1B,GYG2,CACNA1I,BTRC,CANX,BRSK2,RAB28,CLCN4,CLTB,PCYT1B,SLC4A8,HAPLN1,CRY2,CNTNAP2,PHF14,CTNND2,DAPK3,RUSC2,SRGAP3,DYRK1A,EDIL3,EDN1,EPB41,RASGRP2,ETV1,ST3GAL6,ZNF589,EFCAB2,RND1,GLYR1,GPR75,STMN2,GRM8,SOX21,KLF12,ITGA7,MDM4,ADAM22,NELL2,NEUROD1,OMG,PFKFB2,PPP1R1A,LRRN3,TCP11L1,SH3BP2,DZIP1,PKNOX2,RIMS1,TNIK,ZSWIM8,EMC1,SPTB,ARHGEF9,PCDHA5,TIMP4,TRPC3,MVB12B,CAMK1G" Drug 2714_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ACTN2,PLA2G6,CDC42BPA,GAS7,MYOM1,FGF17,BTRC,CFAP410,THSD7A,SCARB1,DLGAP2,CHN1,B4GALT6,TAOK2,SEC14L5,GPRASP1,KIAA0513,DAPK1,SPOCK2,MAMLD1,HIPK3,EFNA3,DMTN,RASGRP2,TBC1D16,OLFM1,BAIAP2,DCTN2,PRELID3A,NCKAP1,SIGLEC8,PCDH17,RUNDC3A,GLRB,CACFD1,MBP,MGAT3,SCAMP5,MYO6,NELL2,PDE1C,TMOD2,PRKAR1B,KLK6,PTPRN2,SUSD4,RGS4,MYH14,ZNF365,LIMS2,SLC12A4,TNIK,DOK5,ZHX3,KLHL4,CUX2,PCDHA6,SLC35G2,TGFBR3,TMOD1,PRMT8,TMPRSS5,VAV2,BEST1,SPHK2,SLC17A7,CAB39L" Drug 2312_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "KIDINS220,NME5,MRTFA,KCNAB2,ATP6V0A1,MTMR3,GYG2,USP2,ADGRG1,CLCN4,AKAP7,ABI3BP,VCAN,CNTNAP2,RIMS3,SPOCK2,HIPK3,ING4,VPS13B,RRAGB,EXTL1,ZNF589,FGF12,FGF13,GCK,GDF9,GLS,GNAL,TDRKH,IRAK3,KLF12,SHISAL1,C2orf72,ITGA7,ITPKA,KCNB1,KCNJ5,LSS,MID1,MMP17,NPR2,PDE4B,PFKFB2,SERPINE2,PLTP,MAPK8,PTPRO,CCDC40,KCTD17,TTLL7,ASAP3,SLC6A8,CXXC4,SMARCC2,SPTB,SPART,CLSTN2,MAPK8IP3,ARC,SLC35G2,HIF3A,TPM3,TRIO,UGT8,FLRT2,SLC17A7,TIGD6" Drug 3638_UP Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ASIC1,AK2,ALK,MRTFA,CDC14B,ASCL1,ATP2B2,CADM3,AZGP1,CAMK2B,SCARB1,CDH18,ZFYVE9,CLCN4,ARMC8,NCOR2,AATK,CSF1R,DNAJC6,KLHL3,CDON,DRD1,EDN1,EFNB3,ELAVL2,EN2,F5,REEP2,KIAA1109,GABRA5,HBS1L,GAP43,RND1,GPM6A,INPP5B,KCND3,KCNJ3,KCNN1,KIF5A,LIG4,MGAT3,MIA2,MN1,ZNF862,NELL2,NF1,OMG,KCNK10,PLTP,MTRF1L,CEP41,RAD52,RNASE1,RXRA,RYR1,S100B,ASAP3,NLGN1,SLC1A7,PKNOX2,EMC1,PHLDB1,AJAP1,SYN2,DMXL2,OBSL1,SPHK2" Drug 4764_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "RALGAPA1,ASIC1,BEGAIN,AMPD3,SEMA7A,PDE8B,CDC42,CHI3L2,ASIC3,AKAP7,CRMP1,AATK,CSF1,ARHGEF10,VCAN,CTIF,C2CD2L,SPOCK3,TMCC2,SGK2,ERCC2,PTK2B,FGF13,FHL1,C1orf61,CSPG5,ZNF44,GAP43,DISC1,C1QL1,RUNDC3A,RAB30,GNG3,TDRKH,NR3C1,TJAP1,IL6R,KCNH2,KCNMA1,KIT,MAOB,NTRK2,PLCD1,PLTP,CDIP1,MAPK8,ELOVL2,NKAIN1,RGS12,TCP11L1,EMID1,ASAP3,SMARCD3,PDZD2,KIF21B,ARHGAP26,ATP10B,MAPK8IP3,POPDC3,TBL1X,TCF7L2,CRTC1,TK2,DAAM2,UGT8,VAV2,SYNC" Drug 6645_UP Glipizide [29094-61-9]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ASPHD1,APBB2,ATP2B2,KSR1,CLDN10,ENTPD2,LARGE1,DLGAP2,CHN2,JAM2,NCOR2,CSF1R,RIMS2,CTIF,BRINP1,MFAP3L,SRGAP3,DUSP9,ING4,RASGRP2,F5,DLC1,ST3GAL6,OLFM1,ERAP1,GNG3,GPR19,GRIK1,ICA1,SHISAL1,IL11RA,KCNJ5,KIT,PACRG,ADAM11,MGAT3,MMP16,ADAM22,NOVA2,PDE4B,PDGFRA,GPR85,PENK,PGAM2,MTRF1L,RIPOR1,TMEM231,C1orf54,RAP1GAP,RGS7,FRMPD1,SLA,SLC1A7,SLC2A5,PKNOX2,ZNF334,CXXC4,SNAP25,SNCA,SYT5,TACR1,ADGRL3,PCDHGB6,SZT2,DAAM2,SPHK2,DPF3" Drug 5916_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ASPHD1,ADORA2A,ADRB2,NME5,ALK,CDC42BPA,APAF1,APC,GAS7,ASCL1,BRINP2,SLC4A4,CD86,RAB33A,STOML1,CSF1,FAM169A,RIMS3,ARMCX2,MFAP3L,PARD6A,DTNA,ELAVL3,SRPK3,CEND1,DLC1,FYN,SRCAP,GLS,PCLO,SPACA9,IL6R,KCNJ5,KCNMA1,KHK,MAP4,MID1,MMP16,MOBP,MYO7A,ZNF862,NF1,PCBP3,PDE1C,PDE3B,WDR25,RGS3,TCP11L1,RPS6KA2,ZNF365,SLC4A3,SLC2A5,ARHGEF40,SLC11A1,COA1,LIMCH1,RBM34,ZCCHC24,DICER1,CHST8,TGFBR3,TMOD1,TMPO,TNS1,CA14,XRCC4,SSPN" Drug 6499_UP Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "PLA2G6,SEMA6A,ALK,APBA2,AQP4,ARHGDIG,ATP2B2,BACH1,SLC16A4,DGKI,TAOK2,ZFYVE9,STOML1,HOMER3,CPS1,RASSF2,DCT,ELMO1,SPOCK3,ATN1,RCAN1,DTNA,EFNB3,EGR3,CACNG2,CAMSAP1,ANKFY1,DCTN2,FAM49B,TXNL4A,GPR75,MSL3,GNAL,GPER1,GRB10,PTGDR2,KLF12,IGF1,ITIH2,KCNJ5,KCNN1,MATK,MBD1,MMP16,MSI1,MYH7,MYT1,GPR88,PCSK2,PPP5C,PROX1,RAB3IL1,ATG16L1,RGS3,GSTCD,PREX2,SLC20A2,ARHGAP26,STX1A,TRIM2,PCDHGA10,SLC44A1,TLR4,CABIN1,HIRA,WIPF1,PLSCR4" Drug 3781_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "NDRG2,ALK,AMPH,KCNAB2,GAS7,PDE8B,ATP1A2,BMP7,GYG2,CFAP410,KALRN,CACNA2D2,CHI3L2,CLCN4,CNTFR,ABCG1,LRIG1,PYGO1,ARHGAP24,CTIF,SPOCK3,ATN1,HIPK3,MBNL2,IRAK4,ING4,EZH1,ABCA8,FAM198B,FABP7,GPR17,GRIA4,GRIN1,GRM7,KCNN1,KIFC3,MARK1,MDM4,MGAT3,MMP16,ADAM22,NOS1,NPPA,NPTX1,NTRK2,NTRK3,PDE4B,PIK3CD,PMP2,RAB3IL1,PNMA8A,KCNIP2,RXRA,STUM,RASA3,CPEB3,SNCA,NFASC,PHLDB1,SYT11,VAMP1,COBL,SEMA4A,PCDHA5,VAV2,PRDM2,MVB12B" Drug 4333_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.18E-10 1.07E-05 3.74E-08 4.26E-07 67 198 "ACTN2,ADD2,ASPH,BMP7,CA12,CACNB2,FAM189A2,CNTNAP2,DAPK3,CTIF,SMG7,SEMA3D,TNK2,SRPK3,STX2,PRELID3A,B3GAT1,ADAM28,FERMT2,GPM6A,GPM6B,HLF,AGFG1,IL6ST,ITGA7,KCNJ5,KCNMA1,KIF5A,KIF5C,TM6SF1,MDM4,NOVA2,NPTX1,NTRK2,NUMA1,OPRL1,PAK3,PBX1,PIK3R1,STRN3,PRRX1,MED1,PPP2R2B,PRKAB2,MAPK7,MAPK8,RET,RGS4,SLC25A36,KIRREL1,TMEM206,NEK11,SEC14L1,STUM,CPEB3,DOCK10,SLC15A2,CXXC4,SOX2,EHBP1,THRA,TMPO,CADM1,FLRT2,SF1,NT5M,KAT6A" Drug 3641_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-10 1.12E-05 3.90E-08 4.44E-07 66 194 "MRTFA,BIN1,GAS7,APOC1,MARK4,CA4,USP2,ARHGEF2,CHRNA4,WHRN,CRMP1,MICAL2,CNIH3,SPOCK3,HS3ST2,CDON,EDN1,SGK2,EFNB3,HSD17B14,CDKL3,EYA1,CAMKK2,FYB1,ZNF44,GABRG2,SEPT9,GPM6A,GRIK5,GRM1,PTPRT,KCND3,KCNN1,LAMA2,ZNF862,NF1,KCNK10,TREM2,PCDH9,RETREG1,PLCD1,NECAB2,ELOVL2,MARCH1,RYR1,ASIC4,ASAP3,DZIP1,SLC11A1,SHANK2,TSNAXIP1,NMNAT2,LMO3,ATP10B,SSTR2,ADGRL3,WSCD1,HIF3A,TK2,TRPC3,OSBP2,PLPPR2,VAV2,VSNL1,KCNAB1,HRASLS" Drug 3900_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-10 1.12E-05 3.90E-08 4.44E-07 66 194 "LTBP4,ASPH,SLC2A11,SCAPER,CACNA1I,LDLRAD4,CDC42,RCBTB2,CHI3L2,CHN2,TPP1,NMT2,WHRN,RCHY1,CRMP1,DYRK1A,C3orf18,SPEG,CEND1,PTK2B,TUBB4A,DLC1,OLFM1,FGFR3,SEMA4D,FLNC,CSPG5,GAD1,INPP5K,GLYR1,GPER1,PCLO,SYNPO,TJAP1,KCNN2,KIT,LMO1,MAPT,MIA2,MX1,MYO9A,ZNF862,PCBP3,RETREG1,NECAB2,MINDY2,ZNF493,TTLL7,ZFP2,ZNF821,ASAP3,SLC1A2,SLC6A9,UNC5B,ATP10B,COLGALT2,MAPK8IP3,TBCEL,SYNE1,UBE3A,VLDLR,SPHK2,PRDM10,SLC17A7,KCNAB1,SSPN" Drug 2700_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.40E-10 1.18E-05 4.06E-08 4.62E-07 65 190 "C3orf14,AMH,BIN1,ANK3,APBB2,DNAH17,ASPH,B3GALT2,RGS11,CACNA1G,CACNB4,BRSK2,HIP1R,USP2,LHX2,DNAJB5,RAB26,FAM149A,COL9A3,NRG2,PDE4DIP,DZIP3,NOS1AP,RIMS3,EGFR,MBNL2,AASS,SORBS3,GABRA3,SIGLEC8,GNAO1,GPD1,STON1,GUCY1B1,RASSF8,IFI16,IGSF1,KCNC1,KCND3,KCNJ5,PACRG,MAPT,MOBP,NCAM1,RGS4,SUGCT,CNKSR2,KANSL3,ZNF415,ATP10B,RGL1,SYT5,TRIM2,FAM189A1,GPR161,TIAM1,TK2,LILRA4,TPM1,AMACR,TRO,OSBP2,MAP3K12,DNALI1,EVI5" Drug CID000002821 CNQX Stitch 2.64E-10 1.30E-05 4.47E-08 5.08E-07 49 126 "HCN2,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CHRM1,CHRNA4,SLC24A2,HAPLN1,EIF4G2,CACNG2,PPP1R1B,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,GLRB,KCNMB4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,MAP4,HCN1,NUCB1,PDYN,PENK,PTCH1,ENOX1,SLC8A2,SOX10,TAC1,TACR1,NTSR2" Drug 6085_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.77E-10 1.36E-05 4.59E-08 5.23E-07 61 174 "ADD3,NME5,APLP1,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,FAM13A,RASGRP2,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,RAB40B,STON1,PCLO,KCNH2,KIF5C,MPP2,MXI1,NEK1,SERPINE2,SERPINI1,PIK3CD,PRPH,RAB3A,RPS6KA2,SH3GL3,PPM1E,ASAP3,ST6GAL1,WDR47,ARHGEF40,ZCCHC24,KIF21B,PEG10,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,GPR161,HEY1,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 5260_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.77E-10 1.36E-05 4.59E-08 5.23E-07 61 174 "ADD3,MARK4,BMP7,ST3GAL5,BAIAP3,CDH18,CLGN,AKAP12,PDE4DIP,SEC14L5,KIAA0513,RIMS3,ARMCX2,DNAJC6,TMCC2,OPTN,EFNB3,FAM13A,AASS,TUBB4A,ATP8A1,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,STON1,KIF5C,MAP2,MXI1,NAP1L3,NEK1,PCBP3,SERPINI1,PIK3CD,PLCD1,GRAMD1C,PRPH,RAB3A,TTLL7,SH3GL3,ASAP3,WDR47,PKNOX2,ARHGEF40,TNIK,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,HEY1,RUNDC3B,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 2385_UP Cortisone [53-06-5]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "ADCYAP1R1,ADORA1,SYT13,SEMA7A,APBB2,PDXK,SPTBN4,ARRB1,PDE8B,CADM3,ATP6V0A1,NRP2,GYG2,CFAP410,CHRNB2,SULT4A1,AKAP6,CNTNAP2,DCAF4,SEC14L5,RIPOR2,TRAPPC9,DYRK1A,EGFR,LRRC23,MTSS1L,HPCAL4,EFCAB2,PDLIM5,GAA,ERAP1,INPP5K,ALDH1L1,KCNMB4,ATF7,GRM3,BRINP3,ITIH2,KCND3,KIF5C,MOBP,MYCN,NOS1,NOVA2,PFKFB2,MAPK7,MAPK8,PROX1,PTN,CCDC40,ZNF365,SLC1A7,SMTN,PKNOX2,TNIK,DOK5,VAMP1,DNMBP,PDLIM2,KIAA1107,TBCEL,RBFOX2,CLIP2,LAT2,ZNF32,SLC17A6,PLSCR4" Drug 4259_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "RALGAPA1,MTUS1,SHROOM2,CDK13,ASPH,SLC4A4,ST3GAL5,ARHGEF7,MAP7,SCARB1,CDC42,CHN2,CNOT8,DNAJB5,QKI,ENTPD4,PDE4DIP,TBC1D5,CNIH3,PLPPR4,PARD6A,DLG3,DPH1,RGS17,VPS13B,COQ7,ETV1,RRAGB,FER,SORBS1,PNMA2,DENND2A,GLI2,GLYR1,KCNMB4,CNTRL,SHISAL1,DIPK1A,INPP5B,JAK2,TM6SF1,NDP,PAK3,RETREG1,RC3H2,PTCH1,PTN,ZSCAN32,PTPRN2,RAD51D,GTDC1,RGS10,GSTCD,CSRNP3,FBXO11,FNDC3A,SLC1A3,MAPK8IP3,PLCB1,KIAA1107,ARHGEF12,ZNF34,SSBP2,VGF,WIPF1,NSD2,KCNAB1" Drug 4213_UP Austricine [10180-88-8]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "TTYH1,ASIC2,FAM135A,BIN1,APC,CDK13,ATP1A3,N4BP2L1,KSR1,SCAPER,CACNA1A,CACNG1,HAP1,LDB2,SCARB1,ADGRG1,RAB33A,HOMER3,FAM149A,IFFO1,NCOR2,ABCG1,DCC,TRAPPC9,EFNB3,ELAVL3,SPEG,FLT1,PDLIM5,GAB1,SYT17,ATP8A2,ADAM28,USP19,STON1,PTPRT,GPR45,ATXN2L,KLF12,IRF8,BRINP3,MARK1,MMP16,MSI1,CTNNA3,CNOT4,OPRL1,PAK3,PDGFRA,PFKFB2,MTRF1L,PRPH,PTPRH,RASGRF1,PBRM1,CARF,PNMA8A,PKNOX2,SNCA,KIF21B,NACAD,ACSBG1,SMG6,TNS1,SEZ6L,LAT2,MKRN3" Drug 6746_UP Calciferol [50-14-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "ASPHD1,SYN3,ACTN2,AGT,NME5,PLA2G6,LTBP4,ALK,MRTFA,DOC2A,GAS7,DDO,APOC1,CDK13,CCDC181,ADGRB2,CACNG1,CALB2,LARGE1,DLGAP1,TPP1,CRMP1,HAPLN1,PHYHIP,MFAP3L,PLPPR4,ATN1,DTNA,DUSP9,ING4,NCALD,F5,FABP7,CAMSAP1,C1orf61,GAD2,ERAP1,GNAL,GPR17,GRIK1,GRIK2,HTR2A,IL12A,KCND3,LSAMP,MYCN,P2RY13,NEFM,P2RY1,TREM2,POU3F2,TMEM231,C1orf54,ENOX1,IL17RB,RASA3,RIMS1,FAIM2,ZHX3,SPP1,IQSEC2,CEP68,TMEM121,SPX,TLR4,PARP6,SLC17A7" Drug 5790_UP Tropine [120-29-6]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "ASIC1,APAF1,APOC1,ARRB2,DDX3Y,ATP1A3,SLC4A4,ATP2A2,NRP2,KSR1,BAIAP3,BTRC,FOXN3,AKAP5,IFFO1,CSF1,ARHGEF10,RIPOR2,RIMS3,ARMCX2,DSCAM,DTNA,EDIL3,ING4,TNK2,APC2,ETV1,REEP2,SEMA4D,GABRA5,ERAP1,DISC1,HPGDS,GLS,GPER1,SPACA9,PADI2,KCNN2,KHK,KPNA5,LMO2,MAPT,MGAT3,ADAM22,TAGLN3,OMG,PDE2A,PLCD1,TNPO2,PROX1,VPS13C,RGS4,SEC61A2,DZIP1,RPH3A,OGDHL,ZHX3,SP4,ARHGAP26,COBL,SYT5,KAZN,ZEB1,PCDHGA1,SEZ6L,ZNF711,ACTR3B" Drug 4634_DN S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.79E-10 1.37E-05 4.59E-08 5.23E-07 67 199 "TRMT9B,AMH,AMPD3,AMT,ANK3,PPFIA4,SEMA4G,PDE8B,ATP2B2,CACNA1I,BTRC,CFAP410,SYNGR3,LARGE1,B4GALT6,ABCG2,HOMER3,AKAP7,WHRN,CABP1,SLC4A8,NCOR2,CTIF,SMG7,DTNB,FCF1,MBNL2,SORBS3,MTSS1L,EPHA5,NRN1,ST3GAL6,FGFR3,AFF2,ZNF44,TRAF3IP2,SIGLEC8,MSL3,GPR17,CACFD1,ICA1,IL11RA,KCNF1,NDP,NDUFA5,NNAT,PRKAR1B,MAPK7,SAMD9,RIPOR1,RALGDS,FOXRED2,ZNF821,ASAP3,SLC1A7,COA1,TNIK,ST5,NCDN,MAPK8IP3,METTL3,OSBP2,XRCC4,SF1,ZNF711,NT5M,EVI5" Drug 3513_DN Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-10 1.44E-05 4.77E-08 5.42E-07 66 195 "ASPHD1,KIDINS220,AP2A2,BEGAIN,AMT,ANK3,PLA2G4C,MARK4,NCOA1,ALDH4A1,CFAP410,CAMK2G,PLAA,ABCG1,CSF1,GREB1,RIMS3,RUSC2,SIDT2,EFNA3,EIF5,EN2,NCALD,SCML2,ZNF589,SCARA3,FLNC,DPYSL4,OGA,GAB1,B4GALNT1,NR3C1,HNMT,INPP1,JAK2,IPO5,LYRM9,NFYA,PALM,SERPINE2,PRKAR1B,PRODH,LRRC49,WDR25,RAD52,RGS3,RGS12,ARHGEF10L,ROM1,WLS,PEX26,FAM214B,BTBD7,CDK5RAP2,RBM34,NCDN,PHLDB1,EXOC7,SATB2,TMEM121,SLC44A1,TK2,PARD3,CABIN1,UBTF,WIPF1" Drug 3553_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-10 1.44E-05 4.77E-08 5.42E-07 66 195 "C1QTNF1,SPARCL1,BIN1,CDC42BPA,KCNAB2,BCAS1,ALDH4A1,RGS9,MTMR3,CACNA1I,HIP1R,EPS15L1,HOMER3,PICK1,AATK,RGS6,OSBPL3,ARHGEF4,CTIF,BRINP1,SPOCK3,DMPK,OLIG2,FGFR3,GFAP,GLYR1,GNAS,GRM1,GRM2,GUCY1B1,IL6ST,KCNN1,SMAD1,MID1,ADAM22,BCO1,NDUFA5,NF1,NOVA2,OPCML,KCNK10,PDE4B,POU6F1,PTHLH,PTPRB,FAM120C,C1orf54,ZFHX4,SUGCT,RPS6KA2,COA1,SPTAN1,DDN,ATP10B,TROVE2,ACSBG1,DMXL2,DOCK9,TNS2,PCDHA6,AHCYL2,SLC44A1,PIK3R5,DNALI1,NUP214,JPH3" Drug 3812_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-10 1.44E-05 4.77E-08 5.42E-07 66 195 "DPF1,NLGN4X,ADGRF5,LTBP4,APC,ARHGDIG,ATP1A2,ATP2B2,AZGP1,CACNA1I,KALRN,SULT4A1,SUSD5,IPCEF1,PDE4DIP,SMG7,NTM,ATN1,ST8SIA3,EGR3,ERBB4,CEND1,OLFM1,PDLIM5,GFER,GRM1,GRM2,GRM3,GUCY1A2,KLF12,KHK,MMP16,NDP,SLCO1C1,NOVA2,NPTX2,NTRK2,SNTG1,PDE2A,GPR173,SERPINI1,PNMA3,PPP2R2B,PRKAR1B,PROX1,WDR25,RASGRF1,GAL3ST4,RNASEL,SEMA6D,SLITRK3,SLC1A6,SLC2A5,PKNOX2,SLC8A1,SLCO1A2,CXXC4,RIMS1,FAIM2,MCF2L,TRO,CA14,VAV2,ZNF154,PARP6,MVB12B" Drug 4148_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-10 1.44E-05 4.77E-08 5.42E-07 66 195 "ASIC2,LTBP4,BIN1,APOC1,CDK13,BRINP2,ATM,ADAM23,CFLAR,SYNJ2,RUNX1T1,USP2,ADGRG1,RAB33A,STOML1,DBT,RABGAP1L,DMPK,DRD1,SNX29,EDN1,EDNRA,CORO2B,FHL1,NSG1,ZNF44,GLI2,GPR22,GRK4,GRIK5,GUCY1A2,HRH3,KLF12,ICA1,KCNJ5,KIF5C,LMO1,MAP4,MID1,ZNF862,NTRK3,PDE3B,PLP1,PLTP,PPP5C,RAD52,C1orf54,RGS12,RNASE1,ASAP3,SLC11A1,SLN,LIMCH1,PDZD2,SP4,PEG10,NPAS3,MAPK8IP3,PHLDB1,TACR1,R3HDM1,TRIO,AMACR,TTPA,CLIP2,SLC30A3" Drug 5237_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.08E-10 1.51E-05 4.97E-08 5.65E-07 65 191 "DPF1,SPARCL1,SEMA7A,GAS7,APP,CDC14B,MARK4,ATP6V0A1,BMP7,GYG2,FOXN3,TAOK2,LHX2,WHRN,TCEAL2,CRY2,FAM169A,SDC3,RIMS2,RIMS3,DBN1,SMG7,CDON,EFNB3,HSD17B14,RASGRP2,CAMSAP1,SORBS1,GAD1,GAP43,PCDH17,GLYR1,ICA1,IL6R,KIF5C,MAP4,MDFI,TM6SF1,ZNF862,NRGN,NUCB1,PLCD1,MTRF1L,LRP12,PTCH1,RALGDS,FAM184A,RGS12,ZNF821,SH3BP2,PPP1R9A,PEX26,FAM214B,LIMCH1,ZCCHC24,KIF21B,ZSWIM8,RGL1,KIAA1107,WSCD1,TRH,TRPM2,HIRA,ITM2C,TIGD6" Drug 4302_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.08E-10 1.51E-05 4.97E-08 5.65E-07 65 191 "ABAT,ADRB2,ARNTL,MARK4,ALDH4A1,N4BP2L1,NOL4,ADGRB2,ST3GAL5,BAIAP3,HIP1R,WHRN,CRY2,ABCG1,PDE4DIP,CNTNAP2,CTH,RIMS3,PLPPR4,SRGAP3,MRNIP,F3,TBC1D16,TAOK3,BAIAP2,SORBS1,FYN,CYP46A1,RND1,GLS,DIPK1A,KIF5C,VWA5A,LSS,MAP2,GIT1,TAGLN3,NRGN,PDE2A,PDE3B,PDGFRA,SERPINI1,PIK3CD,PPP2R2B,PRPH,RGS4,RPS6KA2,SH3GL2,SH3GL3,DZIP1,DOP1A,SPTAN1,THSD1,ELOVL4,RGL1,SYT11,VAMP1,SYT1,COBL,SMG6,TIAM1,CABIN1,TRIM9,SLC17A7,DPF3" Drug ctd:D010622 Phencyclidine CTD 3.49E-10 1.71E-05 5.61E-08 6.38E-07 38 86 "ADORA2A,CDK5R1,CALM1,CAMK2A,CAMK2B,CCKBR,SCARB1,DRD1,FDFT1,GABBR1,GABRA1,GAD2,GAP43,CPLX2,GFAP,GNAS,GRIA4,GRIN1,HTR2A,KCNH1,KCNJ4,MAOB,MBP,KITLG,MOBP,P2RY1,PLP1,PRKCG,RELN,RGS4,KCNIP3,SGK1,ARHGEF9,SYN2,TAC1,SEMA3B,SLC17A6,RTN4" Drug 5523_UP Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.56E-10 1.75E-05 5.65E-08 6.42E-07 67 200 "RALGAPA1,ACTN2,KIDINS220,KIAA1324,AK2,SYT13,BEGAIN,APBA2,KCNAB2,CDK10,DNAH17,CALB1,RUNX1T1,CBFA2T2,ADGRG1,FOXN3,STOML1,CNTN1,AKAP7,SIPA1L1,PHF14,SNPH,TOX,DBN1,EDNRB,MTSS1L,NCALD,CDKL3,KAT8,OLFM1,FHL1,FYB1,HPGDS,POLL,GNG4,GRM7,ITIH2,KCNH2,IPO5,LAMA2,VWA5A,MAN2A2,MEF2C,DDX25,NDP,OMG,PDE4B,GPR85,PACSIN1,PTX3,ATG16L1,ZDHHC14,TCP11L1,PKNOX2,RAB3GAP1,SLC15A2,ELMO2,HECW1,STX1A,SYT5,MCF2L,TBCEL,PCDHGA10,CABIN1,MICAL1,SLC17A7,FAM13C" Drug 3538_UP Condelphine [7633-69-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.56E-10 1.75E-05 5.65E-08 6.42E-07 67 200 "SLC12A5,TRMT9B,AMPD3,OGT,CNTNAP1,APBB2,CACNA1I,CFAP410,SLC16A4,ARHGAP33,CHRNB2,SLIT2,TPP1,WHRN,ENTPD4,VCAN,CNTNAP2,SDC3,GREB1,CTIF,DCC,MAGI2,SHANK1,EDNRA,C3orf18,KIAA1109,AGAP2,ERAP1,SIGLEC8,MYOZ2,ADAM28,MALT1,RND1,GLS,GPM6B,GRIN1,HLF,HSF2,KCNB1,VWA5A,MAP4,MSR1,PDE3B,PLCD1,POU3F4,MAPK7,GDPD2,TTLL7,MYH14,RYR1,SELL,SH3BP2,CPEB3,ST6GAL1,LIMCH1,ARHGAP26,SPTB,RBM26,INKA2,DMXL2,TNS2,PCDHA5,TRIO,TRO,TRPC1,TUBB1,EPM2A" Drug 3203_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.56E-10 1.75E-05 5.65E-08 6.42E-07 67 200 "SYN3,SLC12A5,AGT,APC,PRX,ASPH,DDX3Y,ATP1A3,NRP2,MTMR3,CACNB4,HIP1R,CDH2,CDH10,ADGRG1,HAPLN1,AATK,SIPA1L1,GPRASP1,TOX,ANKMY1,PTK2B,CORO2B,ANKFY1,SORBS1,HBS1L,GAP43,SIGLEC8,LYVE1,RAB30,RAPGEF1,NR3C1,CELF3,PTGDR2,SYNPO,INPP5B,KCNA1,KCNF1,KCNJ5,MAOB,AFDN,ADAM22,MYT1,CNOT4,NPTX1,NTRK2,MTRF1L,NECAB2,MBOAT7,RPS6KA2,ASIC4,ANKRD6,KDM4D,CAND2,CDK19,ATP10B,ACSBG1,PCDHGA1,HIF3A,AP4E1,THBS4,TK2,TMOD1,TRPC1,FAM13C,NLRP3,JPH3" Drug 3044_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.56E-10 1.75E-05 5.65E-08 6.42E-07 67 200 "ADD2,SEMA6A,DDO,LGR5,AQP4,ARHGDIG,ATP2B2,B3GALT2,MPDZ,BMP7,CACNB4,HAP1,TAOK2,NRXN3,PCYT1B,HAPLN1,SUSD5,PDE4DIP,CTNND2,SNPH,DAPK3,DNAJC6,DCT,MFAP3L,TRAPPC9,DSCAM,EDN3,SRPK3,ELN,VPS13B,EPHB1,ANKMY1,OLFM1,FLT1,SIGLEC8,ALDH1L1,MSTN,ZNF276,PRUNE2,PCLO,HRH3,SCIN,KCNJ3,MAP4,AFDN,MYH3,MYT1,NCAM1,NFIX,PRKAR1B,PTPRN2,RNASE1,MYH14,SLC11A1,SLN,PALLD,SOX10,DBNDD2,ATP10B,ASTN2,TACR1,SLC35G2,ATP13A2,TK2,SEZ6L,VAV2,PMEPA1" Drug CID000005275 SR 95531 Stitch 3.67E-10 1.80E-05 5.77E-08 6.56E-07 30 59 "ABAT,DLG4,EEF1A2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRM1,GRM3,GRM5,KCNN2,KCNN3,OPRL1,P2RY1,PTN,SLC6A1,SLC6A11,SIRT2,TAC1,TRPC1" Drug 7535_DN irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.72E-10 1.82E-05 5.77E-08 6.56E-07 60 171 "GRAMD1B,BCAR3,MAP4K3,CDK13,NCOA1,ATP2B1,ARHGEF7,KRIT1,NIPBL,TENM4,OSBPL3,SIPA1L1,PUM1,KIAA0586,DYRK1A,MBNL2,GPHN,TAOK3,CHST15,SEC24B,SYNCRIP,TACC2,CAB39,MBP,MEF2C,MEIS2,MID1,PDE1C,CCSER2,PKN2,REV3L,ZFHX4,LGR4,ATXN1,ATXN2,SCAF8,ITSN1,CHD9,EPN2,ATF7IP,KDM4B,ERC1,ERBIN,ANKRD12,MTCL1,CAMSAP2,WWC1,EHBP1,TCF4,TCF7L2,ZEB1,TCF12,TIAM1,PARD3,KAT6B,TRIO,TRPS1,UBE3A,NAV2,ZNF248" Drug 3696_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "ACTN2,ADD2,SLC12A5,MTUS1,NME5,SEMA7A,APBB1,CDC14B,CDK10,PTCH2,BRINP2,N4BP2L1,MTMR3,GYG2,MAGI1,CBARP,CHI3L2,VAX2,AKAP7,AATK,RIMS3,MYEF2,MFAP3L,ABCC9,ZNF391,OLFM1,FGR,C1orf61,PDLIM5,CGREF1,GAB1,GAP43,GNAS,GPM6A,GRM1,GRM2,GRM3,NXPH3,IL12A,KPNA5,MYH7,NELL2,PBX1,LRRN3,PTPRN2,PTPRO,ZSCAN2,NKAIN1,RAD51D,RFX2,RGS7,RAVER2,RPH3A,SLC11A1,SLCO1A2,IZUMO4,UNC5B,SYT11,SYN2,KLHL4,ZEB1,CRTC1,TEX15,TPM3,SPHK2,NLRP3" Drug 6074_UP Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "AGT,ADGRF5,SEMA6A,ALK,BEGAIN,PLA2G4C,ATP1A3,ALDH7A1,N4BP2L1,GYG2,BRSK2,RHBDL1,CDH2,CRLF1,NCOR2,CSF1,CNTNAP2,RIPOR2,PARD6A,CDON,LRRC23,ERBB4,IGSF6,PTK2B,SCARA3,DPYSL4,FYB1,FYN,ZNF44,GAP43,LPAR4,NR3C1,GRM1,PTGDR2,KLF12,ITGA7,DDX25,ZNF862,NF1,P2RY1,TREM2,PFKFB2,MTRF1L,SAMD9,NUDT11,MYH14,RPS6KA2,RYR1,ASIC4,SLA,SLC2A5,SLCO1A2,IZUMO4,SPP1,SPTAN1,COLGALT2,RGL1,ACSBG1,SYT5,TACR1,WSCD1,CRTC1,PIK3R5,UCHL1,OSBP2,KCNK12" Drug 4005_UP Suprofen [40828-46-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "ASPHD1,ASIC2,ADD2,SYT13,BIN1,CDC14B,CDK13,SYNJ2,BAIAP3,BTRC,CFAP410,CA12,CACNA1D,CDH8,CSF1R,CALY,SEC14L5,SPOCK3,EDIL3,HIPK3,EFNB3,ETV1,KIAA1109,OLFM1,FGFR1,C1orf61,AGAP2,SORBS1,OGA,GAD2,GATM,SPACA9,CACFD1,IL12A,JAK2,KCNF1,KCNJ5,CNOT4,CLDN11,PCDH9,PDE2A,ENPP2,PFKFB4,NLE1,TNPO2,ELOVL2,BEND5,GAL3ST4,ZMAT4,RFX2,PNMA8A,GSTCD,DOCK10,NTNG1,BCAN,DOK5,ZSWIM8,RBM26,COBL,TAC3,OBSL1,CDK20,VGF,LAT2,WNK1,KCNAB1" Drug 5115_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "ALK,AMPD3,APC,GAS7,APLP1,BRINP2,BCL7A,LDLRAD4,CAST,RUNX1T1,NEURL1,FOXN3,CHRNB2,STOML1,VAX2,ABCG2,DNAJB5,HOMER3,WHRN,EDNRA,HIPK3,SEMA3D,C3orf18,APC2,F5,SORBS1,GAD1,SRCAP,LYVE1,GUCY1B1,ICA1,TJAP1,ITGA7,KCNQ3,MMP16,ADAM22,MSRA,NDUFA5,RETREG1,PLCD1,ZNF426,MINDY2,PKN2,PTPRH,ZSCAN2,TMEM231,RAD52,RGS12,MYH14,NEK11,RPS6KA2,LGR4,SEC14L1,FAM102A,ST6GAL1,CNKSR2,SLC6A9,TMCC1,ARHGAP26,ZBTB43,MAPK8IP3,ARC,SZT2,ARHGEF12,ZFPM2,SPHK2" Drug 4773_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "MRTFA,CDC42BPA,APBB2,CDC14B,ATP1A2,LDLRAD4,BTRC,CACNG1,SCARB1,SLIT2,CLCN4,TPP1,FADS2,CNTN1,WHRN,IFFO1,NOS1AP,PHYHIP,DAPK3,SPOCK2,EFNA3,EGFR,EFS,NRN1,ACSL4,FER,FGF1,FGR,FYB1,ALDH1L1,POLL,GRM1,GRM3,CELF3,NXPH3,ITIH2,KCND3,KCNJ9,KCNMA1,VWA5A,MPP2,ENPP2,PLTP,POU3F4,MAPK7,KHDRBS2,PBRM1,SH3GL3,FRMPD1,CNKSR2,LIMS2,IZUMO4,COLGALT2,EPB41L3,EXOC7,TAL1,WSCD1,HEY1,HEY2,RIMBP2,SEZ6L,CHST5,ZNF711,PRDM2,SCG2,KCNAB1" Drug 5689_UP Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "NDRG2,ADCY6,ADORA1,ADRA1B,C1QTNF3,SPARCL1,NOL4,MTMR3,CACNA1I,MYRF,CACNG1,CALB2,CCKBR,SEPT7,FOXN3,STOML1,RGS6,PDE4DIP,ARHGEF4,RASSF2,DBT,SPOCK3,DPP6,DRP2,EFNB3,EGR3,CDHR1,ETV1,F5,FGFR1,FGR,FOXF2,AGAP2,SORBS1,FYN,HTR2A,KCNJ5,KCNN2,SMAD9,MEF2C,NCAM1,NCF2,NF1,PAK3,PCSK2,PHKG1,EPN1,PLXNB1,TRHDE,MINDY2,GDPD2,CCDC40,RASGRF1,TCP11L1,SYNDIG1,SLC2A5,MAST1,SNCA,TROVE2,SYP,TAL1,ADGRL3,TEK,DICER1,SPHK2,SEMA3B" Drug 3375_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "DPF1,ADCY6,AMPH,BIN1,OGT,KCNAB2,GAS7,ASPH,CBFA2T2,CDH8,CHI3L2,SLIT2,TPP1,SULT4A1,NCOR2,SNCAIP,SEC14L5,TOX,DAPK3,RABGAP1L,ELAVL4,ERCC2,PTK2B,TUBB4A,FHL1,C1orf61,DLL3,FYB1,SRCAP,ADAM28,CSDC2,RUNDC3A,GPER1,PCLO,GRIK5,NR3C1,GSTM5,KCNMA1,KCNN1,MEF2C,MX1,NDUFA5,NELL2,NPR2,PPP5C,CEP41,PRODH,FAT4,RPS6KA2,SH3BP2,SH3GL3,RPH3A,ARHGEF40,SLC11A1,SHANK2,SLN,PEG10,AJAP1,ARC,ZEB1,DICER1,TNS1,VLDLR,ADAMTS9,SCG2,EPM2A" Drug 4508_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.75E-10 1.84E-05 5.77E-08 6.56E-07 66 196 "SYN3,ASIC2,C1QTNF3,LTBP4,AMPD3,SEMA7A,CDK13,NRP2,ST3GAL5,CA8,RUNX1T1,NRXN3,ZFYVE9,STOML1,COL9A3,CSF1,MICAL2,PDE4DIP,ARHGEF4,EDRF1,MAML1,MFAP3L,MAGI2,DMPK,NCALD,FOXG1,FAM49B,GAB1,IQGAP2,GNG3,CNTRL,GRIK1,ICA1,IFI16,ITGA7,KCNH2,MMP16,MX1,FXYD7,NPTX2,GPR85,SPATA6,PROX1,SAMD9,RAD52,FBXW7,TCP11L1,SEMA6D,ZNF821,STUM,FRMPD1,RBM34,SCN3B,DOK5,SOX15,ARHGAP26,LHPP,INKA2,COBL,SEMA4A,CRTC1,TLR4,SEZ6L,ZNF225,KCNAB1,GAN" Drug CID003272523 NBQX Stitch 4.16E-10 2.04E-05 6.38E-08 7.25E-07 39 90 "ADCY8,SLC12A5,CA4,CACNA1D,CACNB2,SLC32A1,SNAP91,DRD1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,GFAP,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,CIT,KCND2,BCO1,NUCB1,PDYN,SLC1A2,SLC1A3,TACR1" Drug CID000003007 amphetamine Stitch 4.47E-10 2.19E-05 6.82E-08 7.76E-07 86 284 "ABR,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA2A,ADRA1D,ADRA1B,ADRB2,CACNA1B,CACNA1E,CACNA2D1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CARS,CCK,CCKBR,CHRM1,CS,CSNK1E,DAPK3,DRD1,DNM1L,EEF1A2,MRO,DMTN,ZMYND10,PPP1R1B,FOXO3,CAMKK2,GAD1,GAD2,GAP43,GLRB,LOXL3,MCHR1,GPR37,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HPS5,HTR2A,MYLK2,PACRG,MAOB,NPY,OPA1,OPRL1,PAH,PDPK1,PDYN,PENK,CAMKV,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,KLK6,SIRT2,SNCB,SNCA,SOX10,SYN2,SYT4,MLST8,ZEB1,TRH,NTSR2,RICTOR,SLC17A7,SLC17A6,CAMK1G" Drug CID000001209 L-quisqualic acid Stitch 4.51E-10 2.21E-05 6.87E-08 7.81E-07 62 180 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,DYNLL1,CHRM1,PLCXD3,EIF4G2,TUBD1,CACNG2,TUBB3,TUBB4A,FOLH1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,TUBA8,GLRB,KCNMB4,TUBA1C,GRIA1,GRIA2,GRIA4,PLCD4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4K5,TUBB2B,MAP4,MBP,NUCB1,OMG,PDYN,PLCB2,PLCD1,ENOX1,PLCB1,TUBB2A,TUBB1,PORCN,TUBA1A" Drug 3994_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "N4BP2L1,BCHE,BMP7,SYNJ1,SCAPER,SLC16A4,CBFA2T2,ARHGAP33,DLGAP2,TPP1,RAB26,AKAP7,RIMS2,EDRF1,MYEF2,DRP2,DUSP9,CELSR3,SUGP2,PLXNC1,IRAK4,ZNF391,PRELID3A,OGA,GALC,ERAP1,NEU3,SRCAP,PCDH17,GNAO1,GRIK2,HTR5A,ICA1,IL12A,KIFC3,KIT,NF1,NPR2,NTRK2,PDE2A,SPATA6,POU6F1,PTPRN2,GAL3ST4,CRTAC1,ROM1,TCP11L1,RPS20,KCNIP1,SEMA6D,CSRNP3,ZNF821,MRAS,SH3BP2,ANKRD6,SOX15,IZUMO4,ACSBG1,VAMP1,COBL,EXOC7,RPGRIP1L,CRTC1,CDK20,VGF,ZNF24" Drug 3737_UP Myosmine [532-12-7]; Up 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "ASPHD1,NDRG2,ADD2,KIDINS220,LTBP4,AMPD3,APAF1,APOC1,PPP4R4,KIF1A,NRP2,CRLF1,CHM,CLCN4,SULT4A1,AKAP5,SLC4A8,IFFO1,PDE4DIP,RIMS2,EDRF1,DCC,MFAP3L,MAGI2,DTNA,FCF1,EFNB3,KAT8,KIAA1109,FOXG1,GAP43,GNAL,GNG3,GPD2,GRIK5,GRM7,SOX21,MAP4K5,TJAP1,KCNJ5,LSS,MMP16,ADAM22,NF1,NNAT,CLDN11,PDE2A,PDGFRA,LRRN3,RAD52,KCNIP1,SEMA6D,SCN8A,TRIM46,ZNF821,FNDC3A,SCN3B,KDM4C,SYT11,SYT5,ZEB1,TMOD1,OSBP2,LAT2,KAT6A,RNF146" Drug 5619_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "SYN3,ASIC1,ADORA3,APAF1,KCNAB2,ARHGDIG,ASCL1,SLC4A4,ATP2B2,ADAM23,CA4,LHX2,DNAJB5,PICK1,HAPLN1,NCOR2,CSF1R,MICAL2,SNPH,SRGAP3,NTM,ATN1,EDNRB,EFNB3,EGR3,ELAVL2,ERCC2,PIPOX,FGF13,SIGLEC8,C1QL1,ATXN2L,KLF12,KCND3,KCNH2,KCNJ4,KIT,VWA5A,NOVA2,PFKFB2,CDK14,MAPK8,MAPK10,C1orf54,RASGRF1,CRTAC1,TTLL7,KCNIP1,KANSL3,SLC9A5,CXXC4,KIF13A,KDM4B,NPAS3,MAPK8IP3,SYN2,SYT5,POPDC3,TACR1,WSCD1,PCDHGA1,SLC19A3,TF,TRPM2,FLRT2,SLC17A7" Drug 4160_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "SYT13,APBA2,GAS7,ATP2B2,KSR1,CACNG1,RUNX1T1,CDC42,CDH2,ADGRG1,TAOK2,CNTNAP2,ARHGEF4,HDAC9,MYEF2,DMPK,DSCAM,FAM13A,EGFR,CALCRL,CORO2B,B3GAT1,TBR1,OGA,GABRA5,SIGLEC8,RUNDC3A,GPR22,LPAR4,GRIK5,GRM1,GRM7,KLF12,ITGA7,MEF2C,ADAM22,BCO1,NCAM1,NEUROD2,GPR85,MAPK7,GDPD2,PTCH1,TMEM255A,RAD52,RGS4,MYH14,TRA2B,ST6GAL1,CNKSR2,DZIP1,KANSL3,PKNOX2,SHANK2,SOX10,MAPK8IP3,WSCD1,TNS2,SLC35G2,DNAH7,TPM3,TRIO,KCNK12,ITM2C,PAK5,PHTF2" Drug 6383_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "NDRG2,SYT13,APC,SEMA4G,NRP2,BAIAP3,CACNA1D,CACNB2,FOXN3,TAOK2,NMT2,CRMP1,CSF1,SDC3,FAM131B,RIPOR2,MFAP3L,C2CD2L,KLHL3,EDNRA,FCF1,MBNL2,HSD17B14,EN2,IGSF6,PTK2B,KIAA1109,FGF1,FYN,GAD2,DISC1,POLL,GNG3,GRIK5,CELF3,TJAP1,KCNMA1,L1CAM,LIFR,AFDN,MMP16,NNAT,CNOT4,PAX6,PFKFB2,POU3F2,GRAMD1C,PTPRD,ZFHX4,MYH14,KCNIP1,SATB1,BCAN,SHANK2,SORCS3,SOX2,TROVE2,INKA2,MAPK8IP3,ARC,SMG6,TRO,WIPF1,LAT2,SLC30A3,NUP214" Drug 4127_UP Sulmazole [73384-60-8]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "ASPHD1,TRMT9B,APAF1,APBB2,GAS7,ASPH,BAIAP3,CLGN,TAOK2,VAX2,ARMC8,WHRN,ABCG1,CSF1,GREB1,DAPK1,DAPK3,NTM,ATN1,DYRK1A,EFNB3,EGR3,TRAF3IP2,NEU3,GSTM5,PTGDR2,KLF12,ICA1,KCNJ3,KCNMA1,KCNN1,MSI1,NF1,NTRK3,OMG,GPR85,RETREG1,PLCD1,MAPK10,PTPRB,ZSCAN2,RAB3IL1,RFX3,RGS12,NUDT11,RPS6KA2,SH3BP2,FBXO11,RPH3A,CXXC4,COA1,SMARCD3,SNCA,RBM34,ATP10B,MAPK8IP3,ACSBG1,EXOC7,ADGRL3,KIAA1107,SYNE1,SLC19A3,TRPC3,VAV2,ZIC3,PARP11" Drug 2237_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "NME5,MRTFA,AMPH,GAS7,RGS20,MARK4,BAIAP3,LDLRAD4,CA4,CAMK2B,RHBDL1,KCNAB3,TAOK2,VCAN,DCAF4,EDN1,SRPK3,RCAN2,ATP8A1,FYB1,ZNF44,GABRG2,GAD2,MSL3,GNG3,HPSE2,IL11RA,ITIH2,ITPKA,KCNMA1,MAN2A2,MATN3,NELL2,NPPA,SLC11A2,PALM,PFKFB2,PLCD1,PACSIN1,C19orf57,PRKCB,MAPK7,TMEM104,RAB3IL1,TTLL7,MYH14,KLHDC8A,RPS6KA2,SEMA6D,SCN8A,SH3BP2,SH3GL3,SLC9A5,KDM4B,SOX10,PEG10,ACSBG1,KAZN,DOCK9,CRTC1,TNS1,LAT2,XRCC4,NT5M,KAT6A,NUP214" Drug 4757_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.79E-10 2.35E-05 7.11E-08 8.09E-07 66 197 "ASIC1,ADORA2A,ALK,AMPH,CDC42BPA,ANK2,MARK4,NRP2,CDH18,CDO1,CHM,RCHY1,CPS1,AATK,CSF1,VCAN,DCT,HIPK3,CORO2B,DLC1,CAMSAP1,FHL1,FOXG1,OGA,GAD2,GPR162,GNG3,RAPGEF1,GRM7,GRM8,PTGDR2,KCNH2,KCNMA1,VWA5A,MMP17,MOBP,MSR1,TAGLN3,MYCN,PFKFB2,PLCD1,TNPO2,PKN2,PROX1,PTCH1,ACSM5,C1orf54,SH3BP2,SH3GL3,BCAN,NLGN1,SLC11A1,ZCCHC24,TSNAXIP1,SPP1,PEG10,ATP10B,TEX15,TGFBR3,TMOD1,WIPF1,ZFP37,ZIC3,SYNC,SLC17A7,PHTF2" Drug 5580_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.85E-10 2.38E-05 7.17E-08 8.16E-07 60 172 "ADD3,NME5,APAF1,ST3GAL5,BAIAP3,CDK5R2,USP2,CDH18,CLGN,PDE4DIP,ARMCX2,DNAJC6,JAKMIP2,SRGAP3,EFNA3,EFNB3,FAM13A,MBNL2,PTK2B,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,PCLO,KIF5C,NAP1L3,NEK1,PCDH9,TMOD2,SERPINI1,PIK3CD,LRP12,PRPH,RPS20,SH3BGR,SH3GL3,ASAP3,CPEB3,WDR47,CCDC88A,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,RUNDC3B,UBE2H,DNAJC12,CLIP2,SLC30A3,SLC17A7" Drug 4151_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.05E-10 2.47E-05 7.41E-08 8.43E-07 65 193 "DPF1,AK2,SEMA6A,ALK,BRINP2,CFLAR,SYNJ2,CACNA1G,CALB1,CALB2,KALRN,CAMK2B,SLC16A4,CLGN,CHRNB2,TAOK2,TPP1,SULT4A1,PLCH2,CNTNAP2,RIMS3,CTIF,SPOCK3,DMTF1,SNX29,EDN1,TENM1,EML1,RASGRP2,SPEG,CSPG5,OGA,GABRG2,GAD1,C1QL1,GRM8,SOX21,HLF,ICA1,KCND3,MYCN,POU3F2,PPP5C,MAPK7,PTPRD,RAB3A,RGS4,RGS12,KLHDC8A,STUM,CNKSR2,TNIK,SOX10,SP4,UNC5B,ATP10B,MAPK8IP3,TAC3,KIAA1107,SLC35G2,R3HDM1,TNS1,SEZ6L,SPHK2,DNALI1" Drug 6789_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.05E-10 2.47E-05 7.41E-08 8.43E-07 65 193 "RALGAPA1,ASPHD1,ASIC1,MRTFA,AMT,APC,PPFIA3,DNAH17,ALDH7A1,ADAM23,CFLAR,MTMR3,BAIAP3,CLGN,CLCN4,FADS2,AKAP5,PDE4DIP,GREB1,PPP6R2,SNPH,EFNA3,MBNL2,ING4,MRNIP,OLIG2,ERCC2,AGAP2,GPR153,NSG1,GAB1,CPLX2,GFER,CNTRL,GRM1,IL6R,KCNJ5,MGAT3,ZNF862,FXYD7,NEUROD1,NF1,NPTX1,NLE1,EPN1,PNMA8A,KCNIP1,SH3BP2,ASAP3,FAM214B,SLN,SNCA,WDTC1,ZNF423,SPTB,MLC1,SYP,DMXL2,CRTC1,CHST8,GPR161,ZNF34,TRPC1,FAM155A,ITM2C" Drug 5922_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.05E-10 2.47E-05 7.41E-08 8.43E-07 65 193 "ASPHD1,MTUS1,LTBP4,CDK10,ADGRB2,SYNJ2,BTRC,MAGI1,TPP1,STOML1,NCOR2,ARHGEF10,PDE4DIP,CNTNAP2,FAM131B,SPOCK2,SMG7,RABGAP1L,CDON,ATN1,TOM1,NCALD,EZH1,KAT8,ZNF589,FGFR1,HPCAL4,ZNF44,GAD2,GAP43,ERAP1,ADAM28,GFRA1,KCNMB4,GNAS,GPER1,GRIK2,PADI2,ATXN2L,KCNN2,NF1,NFYA,NOVA1,CDK18,PDGFRA,GPR85,SPATA6,CNNM2,PTAFR,PTN,ARHGEF10L,GSTCD,RPS6KA2,SALL1,SLC15A2,SLN,NACAD,SYT11,FBXW11,TRIO,CADM1,ZNF225,PRDM2,EVI5,PCBP4" Drug 5675_UP Colchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.31E-10 2.60E-05 7.77E-08 8.84E-07 64 189 "LTBP4,AMPD3,ANK1,CDC14B,CADM3,CACNA1I,WHRN,CRYM,AATK,CSF1,CSNK1E,MAML1,BRINP1,GIT2,SHANK1,ATN1,DSCAM,DTNA,EDN1,EGFR,ENO2,ERBB4,REEP2,ATP8A1,HPCAL4,FYB1,GABRA2,GAD1,SRCAP,RAB30,GNG3,PCLO,RAPGEF1,GRM8,GSN,ATXN2L,SHISAL1,INPP5B,ITIH2,KIF5C,MBP,OMG,PFKFB2,NLE1,STRN3,POU6F1,PTPRE,PTPRN,TCP11L1,TRIM46,EPN2,SLC20A2,OGDHL,MAPKBP1,PALLD,JMJD6,SYP,ADGRL3,CHST5,ADAMTS9,SLC17A7,PLSCR4,HRASLS,CAMK1G" Drug ctd:D005473 Fluoxetine CTD 5.91E-10 2.89E-05 8.57E-08 9.76E-07 96 331 "SERPINA3,ADCY8,ADORA1,AMPD2,ARNTL,ARRB1,ARRB2,PDE8B,ATP2A2,CACNA1G,CCK,DCLK1,CNR1,CLOCK,CRY2,SLC32A1,EFNA2,EFNA3,EFNB3,EGFR,EGR3,OLIG2,NRN1,PTK2B,TUBB3,PPP1R1B,FGF1,BAIAP2,GAD1,GAD2,GAP43,GCK,GFAP,GNAS,GPD1,GRIA1,GRIA2,GRIK2,NR3C1,HAPLN2,HTR2A,HES5,IL12A,ITGAM,ITPKA,KCNA6,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNK2,L1CAM,LSS,SMAD1,MBD1,NCAM1,NEUROD2,NF1,NPY,NPTX2,NRGN,NTRK2,NUCB1,OXTR,KCNK10,PDE4A,PDE4B,PDE4D,PDYN,PENK,SERPINI1,PLCL1,PLEC,PLXNB1,PRKCG,MAPK3,MAPK8,RELN,RGS3,ROBO2,S100B,SGK1,CNKSR2,DDN,STXBP1,PLCB1,SYN1,ARC,SYP,ICAM5,TPM1,VGF,VLDLR,XPO1,SLC30A3,SLC17A7" Drug 5209_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.06E-10 2.97E-05 8.57E-08 9.76E-07 61 177 "DPF1,ADD3,NME5,SEMA6A,MARK4,ASPH,BMP7,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TMCC2,OPTN,EFNA3,EFNB3,RASGRP2,STX2,TUBB4A,DPYSL4,SORBS1,FYN,STON1,GRB10,KIF5C,MAP2,MPP2,MXI1,NAP1L3,PDE4A,TMOD2,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,PTCH1,FAM184A,SH3GL3,ASAP3,WDR47,FAM214B,LIMCH1,TNIK,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC17A7,ITM2C" Drug 3312_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.06E-10 2.97E-05 8.57E-08 9.76E-07 61 177 "NME5,ALCAM,ST3GAL5,BAIAP3,CLGN,DOCK4,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,EFNA3,EFNB3,FAM13A,RASGRP2,TUBB4A,HPCAL4,DPYSL4,SORBS1,OGA,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PLCD1,PMP22,PKIA,GRAMD1C,PRPH,LRRC49,SH3GL3,PPM1E,ASAP3,WDR47,PKNOX2,ARHGEF40,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,RPGRIP1L,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 6255_UP Spironolactone [52-01-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "ADORA2A,ADGRF5,MRTFA,CDC42BPA,ANK3,APC,CDK13,PDE8B,NCOA1,CFLAR,BTRC,CAMK2G,MYOM2,ARHGEF2,CSF1,PDE4DIP,CTH,JAKMIP2,MFAP3L,DTNA,EFNA3,MBNL2,CDHR1,VPS26C,F5,GAB1,POLL,GUCY1A2,HPSE2,HSD17B1,IL6R,MAG,MAP4,AFDN,MYCN,NDUFA5,NF1,SLC11A2,OMG,PLTP,LRP12,POLG,PPP2R2B,MAPK8,FBXW7,RPS6KA2,ANKRD6,SLC6A9,SLC11A1,SLC22A4,SOX10,EMC1,ZNF423,SPTAN1,TSPYL2,SYN2,ATP11A,SEMA4A,EXOC7,NSD1,PCDHA5,SEZ6L,PLPPR2,WIPF1,SYNC,KCNAB1" Drug 3336_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "NDRG2,ALK,PPFIA2,APAF1,ARNTL,CDK13,KSR1,BAIAP3,CFAP410,ARHGEF6,PICK1,AKAP6,TOX,SPOCK2,DRD1,HIPK3,EPHB1,ERCC2,ZNF589,AGAP2,PDLIM5,TBR1,RND1,GNAO1,GPD2,KLF12,ITGAM,KCNQ2,AFF1,MSR1,MYCN,NEK1,OMG,OPRL1,P2RY1,PDE3B,PDE4A,PFKFB4,STRN3,LRP12,PTPRO,TMEM255A,GAL3ST4,KCNIP1,SALL1,SEMA6D,ASAP3,SLC6A9,COA1,LIMCH1,PDZD2,KIF21B,TSNAXIP1,HECW1,UNC5B,ARHGAP26,AJAP1,JMJD6,VAMP1,ATP11A,OBSL1,DNAH7,TNS1,BEST1,VSNL1,SPHK2" Drug 4258_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "SLC12A5,PPFIA4,DDO,AQP4,ARSE,PTCH2,ATP1A2,B3GALT2,NOL4,CACNG1,SLC16A4,ARHGAP33,DLGAP1,GPR37L1,CHGA,NRXN3,TMEM59L,AKAP7,COL9A3,NRG2,RIMS2,NOS1AP,CYBB,BRINP1,DCC,SV2B,HS3ST2,TNK2,EFCAB2,DPYSL4,ARPP21,SIGLEC8,MYOZ2,GRIA1,GRM1,ADAMTS6,HPCA,HTR5A,KCNH1,PACRG,MGAT3,CD200,NF1,NNAT,NRCAM,NTRK2,NTRK3,NUMA1,P2RX7,POU6F1,PTPRN2,RNASEL,RTN1,SCN2B,SCN3A,NFASC,SYT5,SYNE1,PHF24,SEZ6L,TRPC3,VAV2,WIPF1,SLC26A10,PRDM2,NLRP3" Drug 3798_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "PLA2G6,LGR5,CD86,ARHGAP33,CACNA2D2,TPP1,CNTFR,AKAP6,MYRIP,ABCG1,ERC2,TOX,BRINP1,DBT,DCT,RABGAP1L,DMPK,DTNB,EDN3,NRN1,HPCAL4,FYB1,GDF9,RND1,GPD1,PRUNE2,ATF7,LILRA2,GPR17,GRM1,GRM2,GUCY1A2,PTGDR2,KLF12,HSD17B1,IGFBP1,KCNH2,KCNJ5,KCNQ2,MAG,KITLG,MMP17,MOBP,NTRK2,CAMKV,POU3F2,LRRN3,PRPH,ZSCAN32,PTPRB,FAM120C,ZMAT4,RGS10,RGS12,RNASEL,SYNDIG1,SEMA6D,TRIM46,SLC1A6,SCN3B,SPTB,OBSL1,TRH,LAT2,FAM13C,NLRP3" Drug 1466_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "SYN3,AK2,TRMT9B,AMPD3,BIN1,APBB2,BCAS1,ASPH,SLC4A4,ATP6V0A1,CFLAR,ST3GAL5,KALRN,HAP1,CARS,USP2,ARHGEF2,CDC42,CDH10,LY86,CRMP1,SDC3,GPRASP1,RIMS3,PHYHIP,DAPK3,HS3ST2,ATN1,DTNB,DYRK1A,EPHB1,ERCC2,DENND4A,C1orf61,GPR153,DLL3,OGA,GNG3,IL6R,KCNMA1,LMO2,MAOB,MBD1,NF1,SETD4,PFKFB2,PLCD1,PACSIN1,GRAMD1C,PLPPR1,PTHLH,ZFP30,BCAN,MYH15,CDK19,STX1A,EXOC7,RPGRIP1L,TK2,TMOD1,TRIO,ZMYND8,MICAL1,PRDM2,HPS4,ST7" Drug 3509_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "DPF1,ADORA1,AMPD3,CDC42BPA,SEMA7A,APBB2,FAM131A,SEMA4G,ATM,CFLAR,KSR1,MYRF,BTRC,CA4,ARHGEF2,SEPT7,LARGE1,CDO1,ADGRG1,FADS2,ARHGEF6,PDE4DIP,CNTNAP2,SDC3,SNPH,SPOCK2,CTIF,TMCC2,DTNA,EDNRA,COQ7,LRRC17,FGFR1,ZNF44,GAD2,LYVE1,GLYR1,LPAR4,SOX21,ITIH2,KCNJ4,MITF,MSR1,MYO7A,NF1,SLCO1C1,PDE3B,PFKFB2,PPARA,MINDY2,RAB3IL1,C1orf54,TMEM206,PKNOX2,SLC12A4,DOK5,ARHGEF12,CRTC1,HEY2,CHST5,TRPC1,AMOT,UCHL1,FLRT2,KCNAB1,ADAMTSL3" Drug 5062_UP Imidurea [39236-46-9]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "ASPHD1,SYN3,ASIC1,NDRG2,APAF1,ST3GAL5,BTK,BAIAP3,CFAP410,SCARB1,AKAP5,IFFO1,HAPLN1,CTNND2,RIMS3,ZEB2,DTNA,SIDT2,COQ7,ERBB4,ETV1,PRELID3A,CYP46A1,GLYR1,SPACA9,GRIK5,GRM8,IL1RAPL1,KCNJ5,KCNQ3,KIFC3,LIFR,MATK,MATN3,MX1,NOVA2,NPR2,NPTX1,NTRK2,PCDH9,PDGFRA,PIK3CD,RETREG1,PPP2R2B,LRRN3,CEP41,PTPRH,PTPRN2,RGS10,FBXW7,KCNIP1,ZFP2,IL17RB,STUM,HKDC1,SLC2A5,KDM4B,ADGRL3,KLHL4,TNS1,TPM3,CA14,VAV1,VGF,ZNF225,PARP6" Drug 2397_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "SRPX,CDC42BPA,APAF1,APC,ARRB2,MARK4,ASPH,CFLAR,CHM,ZFYVE9,TPP1,AKAP7,CSF1,EDRF1,ZNF337,DAPK3,HEPH,EXOG,HS3ST2,DPH1,ST8SIA3,EDNRA,MBNL2,ING4,EIF1,TUBD1,SPEG,FGFR3,GPR153,GLYR1,PRUNE2,GRIN1,PTGDR2,ICA1,KCND2,MARK1,MEF2C,MYCN,NEK1,PDE4B,PLCD1,PLEC,SLC25A23,MINDY2,MAPK8,MASP1,FAM120C,RAD52,SUSD4,RGS3,ARHGEF10L,RAVER2,SH3BP2,SLC20A2,SNCA,SP4,IQSEC2,NPAS3,TROVE2,SS18,STX1A,CAMSAP2,WWC1,TPM3,TRPS1,EMSY" Drug 6827_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "RALGAPA1,AK2,BCAS1,CAPRIN2,ATM,CDK5R1,SCAPER,CAMK2G,SYNGR3,FOXN3,PLEKHB1,RAB28,AKAP7,NCOR1,ABCG1,FAM169A,RIMS2,RUBCN,JAKMIP2,MED12,DTNA,CELSR3,SORBS3,EIF5,EML1,FGFR1,SMC2,GPR153,INPP5K,TXNL4A,COPS8,GLYR1,POLL,GRB10,NR3C1,RNFT2,ATXN2L,KCNH2,KIF2A,SETD4,PLEC,PPP5C,TMEM104,ZSCAN32,LGR4,PAQR6,RAB3GAP1,SHANK2,BTBD7,COA1,SNCA,DOP1A,SPTAN1,ZBTB43,POGZ,COBL,IQCE,TCF7L2,PSD3,TK2,PARD3,VAV1,VGF,REEP1,EVI5,HPS4" Drug 6139_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.09E-10 2.98E-05 8.57E-08 9.76E-07 66 198 "C1QTNF1,BEGAIN,BIN1,CDC42BPA,ANK2,APBB2,CDC14B,KIF1A,SYNJ2,LARGE1,MAGI1,CHGB,CHN2,CHRM4,LHX2,PDE4DIP,DCAF4,SEC14L5,PLPPR4,SV2A,ABCC9,EFNA3,FAM13A,PLEKHA1,ZIC4,CORO2B,BAIAP2,CAMKK2,KHDRBS3,GPR153,ZMYND11,HPGDS,GLYR1,GPD2,GRM3,CELF3,ICA1,MMP16,MYH6,NEUROD1,SLCO1C1,P2RY1,PDE4D,NECAB2,POU3F2,RGR,CARF,SYNDIG1,KCNIP1,RYR1,FERMT1,SLC1A3,EPN2,SNAP25,TMCC1,SOX15,HECW1,PEG10,ARHGAP26,CLSTN2,WWC1,WSCD1,DOCK9,ATP13A2,PARD3,OSBP2" Drug 1672_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.29E-10 3.08E-05 8.83E-08 1.01E-06 60 173 "DPF1,ADD3,SEMA6A,ALCAM,APLP1,MARK4,ST3GAL5,RAB29,CLGN,KIAA0513,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,STX2,ACSL4,DPYSL4,FYN,CYP46A1,RAB40B,STON1,GPR37,KIF5C,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,PTCH1,FAM184A,GSTCD,SH3GL3,PPM1E,ASAP3,ZNF365,WDR47,SMARCD3,ZCCHC24,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,RPGRIP1L,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,GDPD5,SLC17A7" Drug CID000003331 felbamate Stitch 6.31E-10 3.09E-05 8.84E-08 1.01E-06 33 70 "ABAT,GRIN3A,ADGRV1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,ABCB1,PTCH1" Drug 7347_UP Zardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.44E-10 3.16E-05 8.91E-08 1.01E-06 65 194 "RALGAPA1,ASPHD1,NDRG2,AGT,AMH,MARK4,KSR1,SCAPER,GYG2,B4GALT6,FADS2,HOMER3,WHRN,CREM,CSF1,CSF1R,PDE4DIP,FAM169A,GIT2,PARD6A,ATN1,EFNA3,EFNB3,PHF20L1,ING4,STX2,ERCC2,EZH1,C1orf61,TPK1,ALDH1L1,SRCAP,MALT1,TDRKH,CNTRL,GRIK2,NR3C1,HLF,SYNPO,INPP5B,TM6SF1,MEIS1,MPP2,ADAM22,NF1,SLC11A2,EPN1,MINDY2,ZMAT4,RGS12,RPS6KA2,RYR1,SBF1,FBXO11,EPN2,SLC8A1,SHANK2,SMARCD3,ZCCHC24,WSCD1,PSD3,DICER1,UCHL1,PRDM2,ITM2C" Drug 6741_UP Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.44E-10 3.16E-05 8.91E-08 1.01E-06 65 194 "ADCY6,ADORA3,ADRA1B,GAS7,BCAS1,PPP4R4,BCL2L2,DLGAP1,HOMER3,COL9A2,RIPOR2,SPOCK2,MFAP3L,SMG7,SV2B,EDIL3,HIPK3,COQ7,ETV1,CORO2B,DLC1,FER,FGF1,CAMSAP1,TRMO,SYT17,PRUNE2,HRH3,ELOVL5,IGSF1,KCND3,KCNH1,KIT,ADAM22,MX1,NF1,PCBP3,OPCML,PALM,PDE4A,PDE4D,PPP2R2B,CCDC40,RFX2,RGS12,KCTD17,TCP11L1,IL17RB,RIMS1,SOX3,KIF21B,ZHX3,KAZN,TAL1,TCF4,SZT2,HIF3A,GPR161,TPM3,HIRA,TUBB1,UBE3A,LAT2,EMSY,PARP11" Drug 4424_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.44E-10 3.16E-05 8.91E-08 1.01E-06 65 194 "ALCAM,AMPD3,GAS7,PDE8B,MARK4,CADM3,LDLRAD4,CA4,HAP1,CAMK2B,CLGN,CRLF1,ZFYVE9,SIPA1L1,RIMS2,SEC14L5,RUSC2,RABGAP1L,SLC12A6,ST8SIA3,ING4,DLC1,C1orf61,KHDRBS3,GAB1,SRCAP,GFER,C1QL1,GNAL,PCLO,NR3C1,HSF2,KCNN1,KCNQ3,KIF5C,MIA2,MOBP,ADAM22,MYT1,NDUFA5,NEUROD1,NF1,PIK3CD,MTRF1L,PPARA,MAPK7,MAPK8,MAPK10,MYH14,KCNIP1,ATXN1,ITSN1,FAM214B,KDM4B,PDZD2,ARC,ROBO3,ARHGEF12,TK2,PIK3R5,HIRA,PLPPR2,VIPR2,EMSY,EPM2A" Drug 2998_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.44E-10 3.16E-05 8.91E-08 1.01E-06 65 194 "DPF1,SYN3,ABHD6,GRAMD1B,NR0B1,CDC42BPA,APBB2,RASL11B,CACNA1I,CFAP410,CACNG1,CAMK2B,KCNAB3,CHN2,AKAP6,CSF1,PDE4DIP,KIAA0513,SPOCK2,EDN3,OPTN,EFNA3,EFNB3,ING4,ETV1,EYA1,BAIAP2,KHDRBS3,NSG1,GAB1,GPR162,ADAM28,LILRA2,RAPGEF1,SPACA9,GRIK5,SYNPO,KCNB1,LAMA2,CD200,MYO6,DDR2,OPRL1,OXTR,GPR173,PFKFB4,PLCL1,PILRA,RGS4,EMID1,SLC1A3,SLC1A7,SHANK2,CXXC4,SMARCD3,KDM4B,IZUMO4,KAZN,TBCEL,ZNF34,KCTD2,SSBP2,STMN4,KCNAB1,SSPN" Drug CID000093460 pyraclofos Stitch 6.83E-10 3.35E-05 9.43E-08 1.07E-06 43 106 "KCNH8,ANK2,KCNAB2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,KCNAB3,LARGE1,CACNA2D2,ASIC3,CHRM1,CACNG7,CACNG3,CACNG2,GCK,GK,GYG1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,MYL3,PRKCG,SCN2A,SCN2B,SCN4B,SCN7A,SCN3B,KCNAB1" Drug CID000001764 GTP[S] Stitch 6.89E-10 3.38E-05 9.49E-08 1.08E-06 150 592 "ASIC1,GPRIN1,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1B,ADRB2,AP1B1,AGT,NME5,CNTNAP1,ARHGDIA,ARRB1,ARRB2,STX16,ALDH7A1,RGS9,AP1M1,CACNA1I,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNG1,CALM1,CCK,CCKBR,KRIT1,AIFM1,LRBA,CDC42,CACNA2D2,COPB2,ASIC3,CHRM1,MYL6B,CLTC,CNR1,CALY,PLCXD3,GPSM1,SNAP91,DNM1,DNM2,DRD1,DNM1L,EDN1,CACNG7,BSCL2,RRAGB,CACNG3,CACNG2,ACTL6B,AGAP2,AGAP3,FOXM1,NBEA,ARFGAP2,GALR1,MALT1,RND1,CRCP,RAB40B,GNAL,GNAO1,GNAS,GNG3,GOLGB1,MCHR1,RAPGEF4,PLCD4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GPR45,HRH3,HTR2A,MYLK2,KCNJ3,KCNJ4,KCNJ5,KCNMA1,AFDN,MX1,MYL3,NCF2,NME4,NPY,NPPA,OPRL1,P2RY1,KCNK10,CNTN3,PCMT1,PKD1,GPSM2,PLCB2,PLCD1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MASP1,PTH1R,RAB3A,RAP1GDS1,RGS4,RGS12,RIT2,GSTCD,RTKN,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,BEX1,SST,SSTR1,SSTR2,NSFL1C,MLC1,PLCB1,TACR1,EXOC7,TBL1X,TPCN2,GPRIN3,ACTR6,TRH,TRPC1,PITPNB,VIPR2,PLPPR5,SCG2,PLD4" Drug 4460_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.14E-10 3.50E-05 9.80E-08 1.12E-06 63 186 "ACTN2,ADD2,ADD3,TRMT9B,AMT,APAF1,ZBTB10,ATM,IL33,RAB33A,AKAP6,SLC4A7,FEZ1,PDE4DIP,DZIP3,EDRF1,SMG7,NR1D2,TENM1,ETV1,REEP2,ATP8A1,TESK2,KIAA1109,FOXG1,GAB1,RUNDC3A,RND1,MSL3,STON1,GPR37,SPACA9,GRM7,ATXN2L,HNMT,IL6ST,KCNH2,MAP2,NUMA1,PDE4B,PDE4D,SERPINI1,PKN2,PTCH1,PTN,ZCWPW1,ARID4A,RGS3,CARF,TMEM156,ATXN1,TRIM46,SPATA7,CEP68,MCF2L,TCF4,TCF7L2,PSD3,TEX15,FLRT2,LAT2,ZNF225,PLSCR4" Drug 5061_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ASPHD1,ASIC1,NME5,MRTFA,APAF1,DDO,CDK10,ATP1A3,SLC4A4,CADM3,NRP2,CACNG1,WHRN,RCHY1,CREM,RIMS2,FAM131B,INTS1,SRGAP3,EFNB3,PLXNC1,LRRC17,MTSS1L,CORO2B,FGFR1,SIGLEC8,GFER,RUNDC3A,PRUNE2,KCNF1,LIFR,VWA5A,LSS,MAPT,MIA2,AFDN,MMP16,MOBP,CNOT4,NOVA1,OPRL1,PDE4D,PFKFB2,PMP2,RGS10,RGS12,SCN2B,CNKSR2,SLC1A7,SLC11A1,SLN,SNCA,KIF13A,KDM4B,SOX2,ARHGAP26,ACSBG1,SYN2,SYT5,RALYL,SLC44A1,TMOD1,R3HDM1,KCNK12,WNK1,SEMA3B" Drug 2526_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ACTN2,ALK,BIN1,ANK3,AQP6,CADM3,SYNJ1,CA8,CBFA2T2,CHN2,NRXN2,STOML1,CNTN1,NRG2,SIPA1L1,HS3ST2,DTNB,ABCC9,E2F5,HEYL,ING4,TNK2,HSD17B14,NCALD,CDHR1,KIAA1109,PDLIM5,GAD2,ERAP1,INPP5K,GCNT2,GNG4,GPR22,GRIK5,GRIN1,GRM8,IGF1,KCNC1,KCND3,KCNK1,MPP2,NCAM1,PDE4A,PHKG1,MTRF1L,KLK6,PTPRN2,ROM1,TCP11L1,MAP6D1,LRRTM4,SEC14L1,RASA3,PEX26,SLCO1A2,DOK5,PEG10,SPTAN1,ATP10B,CAMSAP2,TBCEL,TCF7L2,TEK,CHST5,VSNL1,SLC17A6" Drug 2697_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "MTUS1,SPARCL1,SEMA6A,ANK2,ASPH,ZSCAN18,ATP2B2,AZGP1,RGS11,BMP7,HIP1R,ENTPD2,NEURL1,CDH10,CHGA,CHN2,CABP1,AKAP5,NRG2,ARHGEF10,RCAN1,BAIAP2,FOXG1,DLL3,TBR1,GAP43,SIGLEC8,ADAM28,GPR75,LILRA2,GRK4,SPACA9,KCND3,KCNQ2,MN1,PDE4A,PRKAR1B,MAPK10,PRPH,WDR25,ACSM5,CCDC40,RALGDS,RGR,RGS4,NEK11,EMID1,ZFP2,SGK1,CNKSR2,CCDC88A,SPTAN1,PHLDB1,ARC,SYP,RPGRIP1L,PHF24,HIF3A,TGFBR3,TIAM1,TNS1,CHST5,TRO,FAM155A,EVI5,PHTF2" Drug 4491_UP Althiazide [5588-16-9]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "SYT13,APBB2,PPFIA3,CDK13,ADAM23,NRP2,BMP7,FUBP1,KALRN,CD86,CDO1,CHN2,CHRNB2,FAM189A2,NCOR2,LRIG1,EDRF1,PYGO1,MAML1,MFAP3L,DMPK,SHANK1,ATN1,DSCAM,DUSP9,DYRK1A,NCALD,C1orf61,MYOZ2,NEU3,GPR17,KCND3,MYO7A,ZNF862,SLCO1C1,NFIX,NTRK2,PBX1,PCSK1,PDE3B,NLE1,EPN1,MAPK8,VPS13C,PTCH1,ZSCAN32,PTPRB,RGS3,SALL1,DOCK10,DZIP1,RPH3A,SLC1A7,PKNOX2,SLC11A1,ZNF334,IZUMO4,ATP10B,TROVE2,EXOC7,DOCK9,TRIO,VIPR2,SLC17A7,KCNAB1,GAN" Drug 5509_UP Resveratrol [501-36-0]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ADRA1D,BEGAIN,CDC14B,ARHGDIG,PLA2G4C,RASL11B,N4BP2L1,KSR1,ASIC3,CNR1,CNTN1,CSF1R,RIMS3,ARMCX2,EGR3,SORBS3,MTSS1L,SPEG,BAIAP2,FGR,DPYSL4,TPK1,GNAO1,GRIK5,GRIN1,GRM1,DHX35,KCNH2,MBD1,GIT1,MX1,NFYA,PALM,CDK18,PFKFB2,PLEC,POU6F1,PRODH,ELOVL2,ZDHHC14,TTLL7,NEK11,TCP11L1,RPS6KA2,MAP6D1,EMID1,PAQR6,SBF1,RASA3,DOCK10,SMTN,ARHGEF40,KIF13A,ZC3H13,SPTAN1,SYN2,KAZN,MCF2L,TAL1,TK2,CABIN1,TRPC1,NSD2,ZNF45,PRDM2,SEMA3B" Drug 4649_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ADD2,ADORA1,ADORA3,MRTFA,AQP4,ASCL1,PTCH2,ASTN1,SLC2A11,KIF1A,BACH1,KSR1,BAIAP3,CACNA1A,CACNA2D1,CAMK2B,RUNX1T1,SLC16A4,CDH10,CLTB,VAX2,CNTFR,COL9A3,RCHY1,SPOCK2,ELMO1,AK5,EXOG,EDIL3,HEYL,HPCAL4,FLT1,B3GAT1,ERAP1,SIGLEC8,GLI2,KLF12,HTR2A,KCNK2,SMAD9,NOVA2,OGG1,PDGFRA,MTRF1L,CNNM2,WDR25,PTPRN,CCDC40,ENOX1,RGS12,MYH14,GSTCD,SCN2B,MRAS,SH3BP2,SLC6A9,SNAP25,KIF21B,IZUMO4,ATP10B,SSTR2,EXOC7,TAL1,DNAH7,TGFBR3,TNS1" Drug 2203_UP Karakoline [39089-30-0]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "NDRG2,SLC12A5,NR0B1,PLA2G6,DDO,FAM131A,BCAS1,CDC14B,CADM3,BMP7,MTMR3,CACNA1I,CHN2,TPP1,ABCG2,CNTN1,CPS1,PDE4DIP,DAPK3,DNAJC6,HS3ST2,TRAPPC9,MBNL2,SORBS3,CEND1,BAIAP2,FLT1,PRELID3A,POLL,PCLO,GRM1,GRM7,GUCY1A2,HRH3,C2orf72,KCND1,KCNJ5,MEF2C,MX1,NPR2,NTRK2,PFKFB4,MTRF1L,WDR25,PTPRN2,PID1,TTLL7,TMEM100,STUM,CPEB3,EPN2,SLC6A8,MYH15,SNCA,TNIK,DOK5,RPGRIP1L,SYNE1,SLC35G2,TEX15,TPM1,TRPC3,RPRM,UGT8,VAV2,CLIP2" Drug 6622_DN Cefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "NME5,MRTFA,TRMT9B,CDC42BPA,PPFIA4,CDK13,DNAH17,CACNA1A,LARGE1,CHM,TAOK2,RAB28,WHRN,CREB5,CSF1,CNTNAP2,MFAP3L,CDON,FEM1B,SIDT2,SUGP2,TNK2,LRRC23,EZH1,CGREF1,GAB1,ZNF44,GAD1,C1QL1,POLL,LPAR4,GRK4,GRM8,TJAP1,IL6R,IL6ST,INPP5B,KIF5C,MAP4,MAPT,MEIS1,AFDN,POLG,WDR25,PTN,BSDC1,KIRREL1,PAQR6,ZNF821,KDM4D,ZNF667,EMC1,ZBTB43,DDN,SPART,MAPK8IP3,SYT11,SYT1,KLHL4,SZT2,DOCK9,THRA,BHLHB9,TNS1,TRIO,TIGD6" Drug 4494_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ARID1A,ADORA1,APAF1,EPB41L5,PPP4R4,ARRB1,CDK13,ATP1A3,BMP7,ST3GAL5,NEURL1,KCNAB3,CNR1,CSF1,CTH,C2CD2L,MAGI2,DYRK1A,CELSR3,APC2,DLC1,FGF13,C1orf61,FYN,NEU3,RND1,GPM6A,TDRKH,GPR17,GRIK5,DIPK1A,ITIH2,L1CAM,LIFR,LSS,ADAM22,DDX25,SLCO1C1,NPTX2,PDE3B,PDE4A,EPN1,STRN3,PTPRH,ZSCAN2,ZMAT4,RFX2,RNASEL,KCNIP1,FRMPD1,HKDC1,RPH3A,PKNOX2,RBM34,MYT1L,SOX15,ZHX3,TCF4,TRIM2,PCDHA5,AP4E1,SEZ6L,TPM3,LMF1,NAV3,KCNAB1" Drug 5090_UP Bufexamac [2438-72-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "AGT,SEMA6A,ALK,SYT13,TRMT9B,CCDC181,KSR1,ST3GAL5,MTMR3,GYG2,CACNG1,MAP7,CDH8,DLGAP1,CRLF1,AKAP7,SH2B1,ABCG1,AATK,SUSD5,ARHGEF4,DCC,MFAP3L,SRGAP3,ST8SIA3,MTSS1L,AGAP2,EFCAB2,FYN,MSL3,ELOVL5,ICA1,KIF5C,PACRG,MAG,MAPT,MMP16,ADAM22,PALM,PDE4B,RETREG1,PLXNB1,SNRK,PTPRH,ZSCAN2,RGS10,RGS12,EMID1,FRMPD1,NTNG1,SLA,SPTAN1,ZBTB43,NACAD,INKA2,SYT1,AP4E1,TK2,LILRA4,TRPC1,ZMYND8,LAT2,MKRN3,REEP1,PRDM2,GAN" Drug 4071_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "ASPHD1,ADRA1D,KIDINS220,AMH,AMPD3,APOC1,AQP4,PPP4R4,ASTN1,ATP1A3,NOL4,ADAM23,CFAP410,CACNB2,BRSK2,DNAJB5,AKAP7,ARMC8,AKAP5,TCEAL2,NCOR2,CSF1,CNTNAP2,ARHGEF4,RIMS2,PLPPR4,DTNA,ST8SIA3,SIDT2,LRRC23,EPHA5,FGF1,SEMA4D,B3GAT1,ZNF44,SEPT9,SRCAP,LPAR4,GRM1,MEF2C,MGAT3,MPP2,ADAM22,NNAT,CLDN11,P2RY1,SERPINI1,MAPK8,WDR25,ZSCAN32,RGS10,DZIP1,SLC1A6,KANSL3,SLN,ACSBG1,ASTN2,MCF2L,TK2,LILRA4,OSBP2,WIPF1,ZIC3,ZNF32,STMN4,SLC17A7" Drug 5604_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.72E-10 3.79E-05 1.03E-07 1.17E-06 66 199 "NDRG2,FAM135A,APAF1,APOC1,ARHGDIG,SCAPER,GYG2,CFAP410,CA4,USP2,WHRN,COL9A3,NCOR2,AATK,PHF14,RASSF2,BRINP1,DRD1,EDNRA,EFNB3,EIF4G2,RASGRP2,EXTL1,ABCA8,FGF1,FHL1,CAMKK2,GAD1,DISC1,SEPT9,MYOZ2,ALDH1L1,GFAP,GLYR1,PRUNE2,PCLO,GRM1,HTR2A,SHISAL1,BCO1,NNAT,NPPA,ENPP2,PURG,LRP12,POU6F1,MAPK10,DCHS2,PTCH1,MRAS,SLC9A5,RIMS1,ZNF415,PDZRN3,TSNAXIP1,HECW1,SPTB,ACSBG1,VAMP1,PLCB1,ANKRD12,WSCD1,TCF7,TRIM2,TRPM2,SLC17A7" Drug 6066_UP Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-10 4.01E-05 1.08E-07 1.23E-06 65 195 "ADRA1D,BEGAIN,CDC42BPA,DDX3Y,ATP2B2,N4BP2L1,CACNA1I,BAIAP3,CAMK2G,SLC22A6,DNAJB5,SULT4A1,OSBPL3,ATN1,ABCC9,EFNB3,DMTN,LRRC23,RASGRP2,DPYSL4,PDLIM5,TPK1,FUT9,GAB1,GABRA5,RUNDC3A,GNAO1,LILRB4,GRB10,SOX21,ICA1,IGFBP1,ADAM11,ADAM22,NF1,NTRK2,P2RX7,KCNK10,PFKFB2,PTAFR,PTHLH,TRIM68,RGS4,RPS6KA2,SCN8A,ASIC4,STUM,PPP1R9A,DOCK10,SLC2A5,SLC11A1,ZSWIM8,BEX1,SPTAN1,NPAS3,PHLDB1,TAC3,ATP11A,PSD3,CRTC1,TPM2,TRIO,TRO,LAT2,ITM2C" Drug 5976_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.13E-10 4.47E-05 1.21E-07 1.37E-06 63 187 "ABHD6,NME5,KIF1A,BAIAP3,CDK5R2,CDH18,CLGN,NMT2,AKAP12,CRYM,PDE4DIP,ARMCX2,DNAJC6,JAKMIP2,SRGAP3,EFNA3,EFNB3,FAM13A,STX2,ACSL4,TUBB4A,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,TDRKH,STON1,PCLO,ITGA7,VWA5A,NAP1L3,NEK1,PCDH9,PDE4A,ENPP2,SERPINI1,PIK3CD,PLCD1,GRAMD1C,PRPH,RADX,GAL3ST4,RPS6KA2,SMPD3,SH3BGR,SH3GL3,WDR47,CCDC88A,ZCCHC24,KIF21B,ELOVL4,RGL1,ACSBG1,SYT11,RPGRIP1L,HEY1,RUNDC3B,DNAJC12,REEP1,SLC17A7" Drug 2199_UP Myosmine [532-12-7]; Up 200; 27.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "SLC12A5,CNTNAP1,APBB2,ARHGDIG,PLA2G4C,PDE8B,ATP2B2,KSR1,CFAP410,ARHGAP33,ADGRG1,CHRNB2,NMT2,CNN3,CNTFR,PDE4DIP,RIMS2,DCAF4,SMG7,CDON,DSCAM,EDIL3,EDNRA,PLEKHA1,ANKMY1,FECH,FGF12,AGAP2,IQCG,PDLIM5,B3GAT1,SIGLEC8,INPP5K,GFER,GNAO1,PTGDR2,KLF12,KCNJ5,KCNMA1,KIF5A,MAP4,MSR1,PCDH9,PLCD1,EPN1,SLC25A23,EPB41L4B,POU6F1,MAPK8,WDR25,PTPN13,RAD52,MYH14,STUM,PEX26,SLC9A5,WDTC1,STX1A,SYNE1,CRTC1,DICER1,SEZ6L,FLRT2,BEST1,SPHK2,PLSCR4" Drug 2147_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "MTUS1,TRMT9B,CDC42BPA,APC,ARNTL,PTCH2,MAP7,CHN2,SLIT2,LHX2,SULT4A1,PICK1,SMARCAL1,NRG2,CREM,RUSC2,SV2B,TRAPPC9,ATN1,EEF1A2,SIDT2,OPTN,EFNA3,ELAVL3,MRNIP,KIAA1109,FGFR1,BAIAP2,NBEA,GALC,ERAP1,SEPT9,GFER,ZNF276,RND1,GNAO1,GNG3,GPR19,GRM7,GSTM5,IGSF1,KIF2A,NNAT,NUMA1,OCRL,PDE4A,PLCL1,RAB3A,ACSS3,RFX2,SEC61A2,SBF1,CXXC4,SNCA,SPTAN1,SPTB,TSPYL2,MAPK8IP3,ADGRL3,TBCEL,HIF3A,TIAM1,SEZ6L,TRPC1,ZMYND8,FLRT1" Drug 2788_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "KIAA1324,ANK1,DDO,BCAS1,PLA2G4C,ARSE,DNAH17,RASL11B,SLC4A4,CACNA1I,ARHGAP33,ASIC3,TAOK2,RIMS2,SGK2,FRY,CELSR3,DMTN,SPEG,ZNF589,CAMSAP1,DLL3,FYB1,GAB1,GAD2,SIGLEC8,DISC1,GFER,HPGDS,ELOVL5,TJAP1,ITIH2,KCNQ3,VWA5A,MGAT3,ZNF862,NELL2,SNTG1,PDE1C,CDK14,CDIP1,ELOVL2,RAB3A,RAD52,RGS12,RPS6KA2,SYNDIG1,SLC1A7,SLN,KDM4B,TSNAXIP1,EMC1,HECW1,ATP10B,AJAP1,SYN1,PCDHGA10,CABIN1,UGT8,WIPF1,REEP1,CA10,KCNAB1,PARP11,RNF170,DPF3" Drug 3825_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "APAF1,AQP4,ARSE,ASCL1,CCDC181,MYOM1,LDLRAD4,CACNA1D,CAMK2B,DLGAP2,CDO1,CHI3L2,TAOK2,TPP1,RAB26,CABP1,AATK,CNTNAP2,C2CD2L,SV2B,ATN1,DTNA,ABCC9,EPHB1,CEND1,SORBS1,GABRG2,DISC1,ALDH1L1,SRCAP,GFRA1,LYVE1,GRIA4,GRM8,AP4S1,IRAK3,PTGDR2,KLF12,C2orf72,KCNN2,LSS,MIA2,MYT1,NPTX1,NRCAM,NUMA1,SNTG1,GPR85,PGAM2,SPATA6,FSD1,LRRN3,PTN,KLHL11,CNKSR2,SLN,FAIM2,MAPK8IP3,SYN2,ATP11A,SEMA4A,TCF7,PCDHGB6,HIF3A,SEZ6L,TUBB1" Drug 5737_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "APAF1,DDO,ARHGDIG,DDX3Y,BMP7,ST3GAL5,CACNB2,CACNG1,HAP1,SCARB1,HOMER3,COL9A3,CSF1,CSNK1E,CNTNAP2,NOS1AP,TOX,SPOCK2,CTIF,SV2B,HS3ST2,EFNA3,COQ7,CORO2B,FGFR1,FOXG1,TBR1,GABRA2,ZMYND11,ERAP1,SRCAP,GNAL,GNAO1,GPR17,GRK4,HLF,HPSE2,KIF5A,MEF2C,AFF1,CD200,KCNK10,PDE4A,PIK3R1,SPATA6,PRKAR1B,MAPK7,ZCWPW1,RGS4,NEK11,SCN8A,BCAN,SLA,SLC11A1,ZNF334,SPTAN1,LHPP,ATP10B,TCF4,AP4E1,ZNF34,LMF1,PRDM2,STMN4,MVB12B,NUP214" Drug 4447_UP nordihydroguaiaretic acid; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "ANK2,BACH1,PROM1,CA12,CACNA1D,HAP1,CH25H,CBS,CHRNA4,RAB33A,NRXN3,ABCG1,CSF1,DCT,TRAPPC9,EGR3,ELAVL3,FGF1,FYB1,ZNF44,GAD2,GATM,ALDH1L1,CYP46A1,ADAM28,GLI2,GNAO1,TDRKH,LPAR4,CACFD1,IL1RAPL1,KCNB1,KCNN2,LMO1,MARK1,MMP17,MOBP,ADAM22,NELL2,SLCO1C1,NPPA,NPTX1,PFKFB2,CAMKV,PLP1,PLXNB1,PTPRD,FAT4,RGS12,RIT2,SALL1,CNKSR2,KANSL3,PKNOX2,ZNF334,NCDN,AJAP1,ATP11A,TCF7,DOCK9,HIF3A,TRIO,AMACR,TRO,FAM13C,NLRP3" Drug 3131_UP Scopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "SYN3,PLA2G6,SPARCL1,ALK,TRMT9B,AMPH,ANK3,APBB2,AQP4,PPP4R4,CACNA1I,CACNA1D,KALRN,LARGE1,SLC24A2,SULT4A1,CNN3,PICK1,CREM,AATK,PDE4DIP,CTNND2,ARMCX2,SIDT2,ELAVL3,MTSS1L,FGFR1,HPCAL4,FOXG1,DCTN2,GPR153,ALDH1L1,PRUNE2,GPR22,GRIK2,GRIN1,ICA1,SCIN,KCND3,KCNN1,MAP4,ADAM22,NPY,NTRK2,OMG,PFKFB2,CAMKV,PPP2R2B,RELN,ENOX1,TTLL7,ROM1,NEK11,SCN2A,SMTN,LHPP,ACSBG1,WWC1,PSD3,CRTC1,TJP1,DAAM2,FLRT2,LMF1,ZIC3,TFIP11" Drug 1474_UP Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-10 4.79E-05 1.26E-07 1.44E-06 66 200 "TKTL1,C1QTNF3,MRTFA,AMPD3,APLP1,DNAH17,ASPH,BRINP2,ALDH4A1,SLC4A4,CFLAR,CDK5R1,ST3GAL5,SCAPER,GYG2,CACNA1I,NEURL1,ARHGAP33,SULT4A1,WHRN,ARHGEF10,DAPK3,MFAP3L,LRRC23,FGFR1,FOXG1,IQCG,ALDH1L1,GLYR1,GRIK5,HNMT,LSS,MAN2A2,MDM4,MSI1,MYO7A,NELL2,PCBP3,CLDN11,RETREG1,POU3F4,LRRN3,MAPK8,RELN,RAB3A,TMEM255A,RAD52,ZDHHC14,ZNF365,SLC2A5,EMC1,ARHGAP26,SPTAN1,MCF2L,IQCE,SYNE1,CRTC1,HIF3A,CHST8,MICAL1,WIPF1,KCNK12,SLC30A3,KCNAB1,NUP214,SSPN" Drug ctd:C109476 epoxiconazole CTD 1.01E-09 4.95E-05 1.30E-07 1.48E-06 99 348 "ACTN1,PLA2G6,LRRC7,DOC2A,DPP10,ANXA7,ALS2,BID,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CAMK2B,CAMK2G,CARS,RGN,CD81,CHGA,DLGAP3,NRXN1,NRXN2,HECTD1,AHCTF1,NSL1,CHD1L,C2CD2,FEZ2,TM9SF4,SIRPA,DBT,DCC,MAGI2,DDX46,G3BP2,DLG4,DPP6,CACNG7,EGFR,MBNL2,AASS,EIF4G2,ERBB2,ERBB4,PIPOX,F5,CACNG2,FGF1,VTI1B,FYN,GABRA4,GABRB1,GHR,GLS,RAPGEF4,STMN2,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,IL1RAPL1,IGF1,ITIH2,HECTD2,ADAM11,NF1,NRCAM,NTRK2,PC,ABCB1,PPARA,RELN,MDGA2,RBBP8,ROBO1,RXRA,HES6,TNFRSF19,SMPD3,NLGN1,SLC1A2,SLC1A6,RAB3GAP1,SHANK2,SLIT1,SMARCA4,UNC5B,STXBP1,NSFL1C,FAM168A,SYP,ENHO,TSC2,CADM1,SLC13A3,ETNPPL,ITM2C" Drug 4423_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "ARID1A,PLA2G6,MRTFA,GAS7,APLP1,SLC2A11,CADM3,MTMR3,LDLRAD4,CAMK2B,CBFA2T2,FADS2,CNTN1,NECTIN3,CPS1,SEC14L5,RIMS3,CTIF,RABGAP1L,ATN1,RCAN1,HIPK3,EN2,DENND4A,FGFR1,CAMSAP1,FHL1,KHDRBS3,DISC1,SEPT9,ALDH1L1,RUNDC3A,GLYR1,GNAS,IL6ST,ITPKB,KCNN1,KCNN2,NEK1,NEUROD1,SERPINE2,SLC25A23,LRP12,MAPK7,GRAMD1C,RPH3A,PEX26,PKNOX2,WDTC1,EMC1,MAPK8IP3,AJAP1,PLCB1,SZT2,TK2,TMOD1,R3HDM1,TRIO,FAM155A,MICAL1,SPHK2,SYNC,EMSY,SLC17A7,GAN" Drug 3542_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "FZD9,PRX,DNAH17,ATP6V0A1,CFLAR,ST3GAL5,CACNA1D,ARHGEF1,CHRNB2,COL4A5,CSF1R,SDC3,DOCK4,RABGAP1L,DTNA,DUSP9,DYRK1A,EDNRA,SGK2,PLXNC1,DMTN,MTSS1L,FGFR1,IQCG,PDLIM5,GALC,MALT1,GNAO1,ATXN2L,ICA1,MBD1,MID1,AFDN,MYO7A,NDUFA5,NPY,PCBP3,NTRK2,LRP12,SAMD9,VPS13C,ZSCAN2,TCP11L1,RPS6KA2,SALL1,SYBU,SLC4A3,EPN2,FAM214B,SLN,FAIM2,ZCCHC24,THSD1,MAPK8IP3,PLCB1,ASTN2,PCDHA5,TK2,R3HDM1,TPD52,TRIO,TRPM2,CLIP2,XRCC4,DNALI1" Drug 6000_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "ADORA1,AP2A2,ADGRF5,C1QTNF3,SPARCL1,CDC42BPA,APC,PLA2G4C,CACNA1D,INA,SLC16A4,CBFA2T2,CACNA2D2,TMEM59L,DNAJB5,SLC4A7,NECTIN3,TBC1D5,MAGI2,PARD6A,DTNA,EDN1,EGFR,ING4,PRELID3A,FYB1,INPP5K,GLS,PRUNE2,GPER1,HLF,LIG4,PACRG,MAN2A2,MEF2C,AFDN,ADAM22,NTRK2,PDE3B,PENK,MAPK7,RELN,CNTLN,RAB3IL1,SLC6A15,KCTD17,WLS,KCNIP1,ASIC4,RASA3,SH3BP2,ASAP3,PKNOX2,ZCCHC24,ZNF423,VAMP1,PLCB1,POPDC3,SZT2,DOCK9,SLC35G2,DICER1,UCHL1,DNALI1,NUP214" Drug 3029_UP Dimethadione [695-53-4]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "SLC12A5,DDO,AQP4,ASPH,SLC2A11,MPDZ,RGS11,BMP7,CFAP410,KALRN,RUNX1T1,USP2,INA,CHGB,LHX2,RIMS2,DCC,DRD1,EDN3,PLXNC1,ETV1,ANKMY1,F5,TUBB4A,KIAA1109,OLFM1,FGFR3,FHL1,GFER,ZNF276,PCSK1N,MCHR1,PCLO,GRIK1,AP4S1,HPSE2,KCNJ3,KCNMA1,MAPT,MATN2,AFDN,ADAM22,NELL2,OPCML,ABCB1,POU6F1,MAPK7,SLC6A15,SEC61A2,RPS20,SLCO1A2,CXXC4,DOK5,CLSTN2,ARC,WSCD1,PCDHGB6,PHF24,TF,AP4E1,TJP1,TMOD1,KCNK12,PMEPA1,JPH3" Drug 5063_UP Diprophylline [479-18-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "ADORA2A,NME5,SEMA7A,MARK4,ATP1A3,STX16,NRP2,FUBP1,CACNA1I,CACNA1A,HAP1,SYNGR3,RAB28,RAB26,MYRIP,HAPLN1,PDE4DIP,GPRASP1,DTNA,SIDT2,PLXNC1,COQ7,ETV1,CEND1,FGFR1,AGAP2,CGREF1,OGA,GAB1,ALDH1L1,GPR17,GRM7,PTGDR2,TJAP1,LIFR,LSS,MATN3,KITLG,LYRM9,NELL2,SLCO1C1,GPR85,PFKFB4,LRRN3,MAPK10,GRAMD1C,PTH1R,RAB3IL1,KCTD17,GSTCD,IL17RB,RASA3,DOCK10,HECW1,DDN,ATP10B,ASTN2,TBCEL,KLHL4,DOCK9,RPRM,WIPF1,PRDM2,GAN,SENP7" Drug 3604_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "TKTL1,NDRG2,GRAMD1B,SPARCL1,LTBP4,MRTFA,AMPH,APLP1,MARK4,ATP2B2,ADGRB1,INA,CACNA2D2,RCBTB2,TAOK2,MICAL2,DGKG,CTIF,DPP6,EFNB3,TNK2,C3orf18,RASGRP2,PIPOX,F5,FABP7,DCTN2,SORBS1,FYB1,GAD2,MALT1,RUNDC3A,RND1,GNG3,GPER1,PCLO,GRM1,GSTM5,IL11RA,KCND3,MBP,NELL2,OPRL1,PACSIN1,POU3F4,MASP1,PTAFR,ELOVL2,RNASEL,PNMA8A,SYNDIG1,SELL,ASAP3,SHANK2,CAND2,SYN2,POPDC3,TCF4,PCDHGA1,TPM2,UCHL1,NT5M,PRDM10,SCG2,SLC17A7" Drug 2818_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "KIDINS220,NME5,APBB2,APC,GAS7,PPP4R4,CAPRIN2,ALDH4A1,CADM3,MTMR2,GYG2,CACNA1D,HAP1,CAMK2G,CLGN,LHX2,FAM189A2,VAX2,SULT4A1,CSF1,MFAP3L,LYPD1,RCAN1,HIPK3,SORBS3,BAIAP2,STON1,GPR22,EML4,INPP5B,KCNJ3,KHK,LMO2,SMAD1,MIA2,MOBP,MX1,ZNF862,NF1,NTRK2,PIK3CD,LRP12,MINDY2,GON4L,ATG16L1,FAM184A,GTDC1,SUPT20H,BTBD7,CDK19,ZBTB43,PLCB1,KAZN,DMXL2,TCF7L2,SYNE1,CRTC1,CHST8,SLC44A1,TMOD1,HIRA,MICAL1,WIPF1,ZNF74,DNALI1" Drug 4122_DN Boldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "ADORA2A,KIDINS220,AP2A2,AMH,AMPD3,BIN1,SEMA7A,APLP1,MARK4,SCAPER,CAMK2B,ADGRG1,PLEKHB1,TAOK2,TPP1,STOML1,CLTB,CPS1,SH2B1,CYBB,RIMS3,RUSC2,SGK2,EFNB3,CELSR3,VPS26C,ATP8A1,FGFR1,CAMSAP1,KHDRBS3,GPR153,HBS1L,GLYR1,RAB30,GPER1,SPACA9,GRIK5,DHX35,TJAP1,IL6ST,IL11RA,ITIH2,KIF5A,IPO5,LMO2,VWA5A,SERPINI1,PIK3CD,ROM1,CPEB3,FUZ,SLN,WDTC1,SPTAN1,CLSTN2,THSD1,PLCB1,ATP11A,PDLIM2,ARHGEF12,R3HDM1,LAT2,XRCC4,HPS4,NUP214" Drug 2097_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-09 5.09E-05 1.31E-07 1.49E-06 65 196 "NDRG2,KCNAB2,APC,APOC1,PPP4R4,SLC4A4,ATP2A2,ALDH7A1,KIF1A,NRP2,HAP1,SCARB1,SYNGR3,RAB33A,NRXN2,ARMC8,SH2B1,FAM169A,FRMPD4,KIAA0513,ELN,SEMA4D,SORBS1,ZNF44,SIGLEC8,ATP8A2,INPP5K,AHDC1,C1QL1,GLI2,GNG4,ICA1,IL11RA,MAPT,SCAMP5,GIT1,ADAM22,MSR1,PAK3,PIK3R1,SEPT4,POU6F1,RAD52,KCTD17,SELL,STUM,DZIP1,BTBD7,SNCA,KDM4B,EMC1,SPTAN1,DDN,VAMP1,TACR1,CHST8,TIAM1,TLR4,CABIN1,PRMT8,TRPC1,VLDLR,TRIM9,ZNF74,KCNAB1" Drug 5417_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.05E-09 5.15E-05 1.32E-07 1.50E-06 60 175 "ADD3,NME5,ST3GAL5,BAIAP3,CDH18,CLGN,DNAJB5,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TMCC2,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,DPYSL4,SORBS1,FYN,CYP46A1,C1QL1,RND1,GLS,STON1,KIF5C,VWA5A,MITF,MXI1,NAP1L3,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,TTLL7,SH3GL3,ASAP3,WDR47,PKNOX2,SMARCD3,TNIK,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,ZEB1,TRIM2,HEY1,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 4429_UP "ICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.10E-09 5.40E-05 1.38E-07 1.57E-06 64 192 "NDRG2,FAM135A,ANK2,LGR5,CDC14B,KSR1,BMP7,LDLRAD4,KALRN,NEURL1,MAGI1,RAB33A,TPP1,CABP1,IFFO1,LRIG1,FEZ1,SPOCK2,MAGI2,RABGAP1L,DYRK1A,EDN3,SEMA3D,EPHB1,CORO2B,ST3GAL6,FGF1,OLFM1,CAMSAP1,SEPT9,SRCAP,RND1,CACFD1,GRM8,IL1RAPL1,SOX21,PADI2,HPSE2,TJAP1,ITIH2,LMO2,VWA5A,NPTX2,PDGFRA,ENPP2,GPR85,PTAFR,ACSS3,TCP11L1,KCNIP1,SALL1,ZFP2,PKNOX2,SLC11A1,ZNF334,HECW1,ATP10B,NCDN,PHLDB1,PCDHGB6,OBSL1,CRB1,RIMBP2,TPM3" Drug 5882_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.16E-09 5.70E-05 1.45E-07 1.65E-06 63 188 "ABAT,ASPHD1,ADRB2,EPB41L5,PPP4R4,ARNTL,ST3GAL5,BAIAP3,CD86,REPS2,ARHGAP22,WHRN,ABCG1,PDE4DIP,CTH,PLPPR4,EFNA3,RGS17,ATP8A1,SORBS1,PNMA2,FYN,RND1,STON1,GPR37,TPPP,GUCY1B1,KIF5C,KIFC3,LIFR,VWA5A,MAP2,MAPT,MMP16,PCDH9,PDGFRA,SERPINI1,PLCD1,PRPH,TMEM231,ENOX1,RGS4,FBXW7,RPS6KA2,SH3GL3,ASAP3,DZIP1,FAM214B,WDTC1,TNIK,BEX1,ARHGAP26,SPTAN1,THSD1,CEP68,RGL1,SYT11,SYT1,COBL,SSBP2,DNAJC12,TRIM9,PLSCR4" Drug 3177_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.16E-09 5.70E-05 1.45E-07 1.65E-06 63 188 "DPF1,ABHD6,ADD3,SYT13,APLP1,CDC14B,BMP7,ST3GAL5,RAB29,BTRC,CLGN,UBE2L6,FAM149A,CABP1,KIAA0513,ARMCX2,TSPAN5,EFNB3,MBNL2,ACSL4,IQCG,SORBS1,FYN,CYP46A1,STON1,NR3C1,KCNC1,KIF5C,MITF,MPP2,NEK1,SERPINI1,PIK3CD,PMP22,DIRAS2,PRPH,GAL3ST4,TTLL7,RPS6KA2,RPS20,SH3GL3,PPM1E,ASAP3,SYBU,WDR47,ZCCHC24,KIF21B,SPTAN1,ELOVL4,RGL1,STXBP1,ACSBG1,PLCB1,TGFBR3,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,GDPD5,SCG2,SLC17A7" Drug ctd:D058185 Magnetite Nanoparticles CTD 1.20E-09 5.86E-05 1.49E-07 1.69E-06 289 1326 "CPNE2,NDRG2,ADD3,CDC7,GRAMD1B,AGT,ALCAM,BBOX1,AMPD3,CDC42BPA,ANK3,SEMA7A,FGD2,APOC2,PPFIA3,USP37,SEMA4G,CASK,CADPS,PDE8B,ASPH,PTCH2,ATP2B1,N4BP2L1,BCL7A,NRP2,BLM,CFLAR,FUBP1,SCAPER,JAZF1,OSGIN2,CACNA1A,CACNA1B,CAMK2D,CANX,CAPN3,CAST,SPAG9,USP2,SLC16A4,CD86,CBFA2T2,CDK11B,CDH10,ZNF445,CDO1,UBE2L6,CHN1,LHX2,NRXN3,CLU,CLTA,CLTC,HECTD1,ARHGEF6,SLC4A7,CP,NECTIN3,RBM39,ANKRD44,GDA,ABCG1,CSF1,FEZ1,MICAL2,PDE4DIP,CST3,DZIP3,SDC3,CTH,RIMS2,ST18,CX3CR1,CYBB,HDAC9,ZFYVE16,RASSF2,TBC1D5,ACY3,MATR3,AIF1L,ZNF804A,ZEB2,MFAP3L,CEP170,MAGI2,ZC3H11A,DDX46,ALKBH8,SACS,MTX3,KBTBD11,DMPK,NR1D2,CASP8AP2,PDCD6IP,RCAN1,ARRDC4,EDIL3,WDPCP,EEF1D,SH3GLB1,PHF20L1,EGFR,MBNL2,EGR3,ENO2,EPB41L2,ERBB4,IGSF6,ANKMY1,TLR7,F3,FAM198B,ACSL4,PRAM1,ATP8A1,ST3GAL6,FCGR3A,SLC9B2,FGF1,SYNCRIP,ZMYND15,SMC2,USP16,PDLIM5,FAM49B,TRIM16,ZNF605,MPP6,FYN,NCKAP1,ERAP1,ALDH1L1,SESN1,ADAM28,MALT1,BRD8,HPGDS,ZNF638,GNG4,LILRB4,GPD2,MCHR1,NR3C1,GSN,KIF3A,KAT7,GUCY1B1,RASSF8,TOX2,PADI2,IFI16,IGF1,IGFBP1,NKD1,SCIN,IL6R,IL6ST,ITGAM,ITGAV,JAK2,KIFC3,KIT,STXBP5,LIG4,LIMS1,SYTL4,LSS,PACRG,SMAD9,GPR155,AQP11,LDLRAD3,MEF2C,MID1,MOV10,DDX25,LAYN,NFE2L2,NFIX,CNOT4,NPY,NPTX1,SLC11A2,SETD4,PDE1A,PDE4B,ENPP2,GPR85,ABCB1,SERPINI1,PIK3R1,ZFYVE21,SLC25A23,STRN3,RC3H2,PILRA,MINDY2,TATDN3,PRKCB,MAPK8,PXK,SPDL1,ZIK1,TUG1,USP47,RBBP6,RBBP8,ZDHHC14,REV3L,RNASE1,NUDT11,ZFHX4,MYH14,RPS6KA2,HUNK,RTN1,ATXN1,SFPQ,DOCK10,CHD9,ST6GAL1,LIMS2,SLC6A9,ZNF430,SLC8A1,CCDC88A,SLC11A1,SLC20A2,SLC22A4,FAM126B,KIF21B,SPP1,KDM4C,ZC3H13,ZBTB43,RBM26,SRPK2,TROVE2,SMOC1,STAC2,SULF2,FGD4,SYN1,ANKRD12,SEMA4A,TCF4,TRIM2,TCF12,NSD1,SIK3,TF,AKTIP,SLC44A1,DDHD1,TLR4,ZFP91,TMPO,TNFRSF1B,PRRT1,NR2C2,PDSS1,STXBP4,TRPS1,ZMYND8,RFTN2,TTC3,USP1,MGAT5B,VLDLR,WIPF1,AGMO,AMZ1,PMEPA1,PRDM2,EVI5,NAV2,FIP1L1,FAM13C,RTN4,HNRNPA3,JMJD1C,NLRP3,TTC7A,ADAMTS10,SPATA13,SENP7" Drug CID000115114 DCG-IV Stitch 1.21E-09 5.93E-05 1.50E-07 1.71E-06 32 68 "ADORA1,ADORA2A,ADORA3,BSN,CACNA1A,CACNA1B,CACNA1E,CREM,SLC32A1,GAD1,GAD2,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNJ3,MAP4,OGDH,PENK,SLC1A2,SLC1A3,SLC1A6,TSN,SLC30A3,SLC17A6" Drug ctd:D003633 Dichlorodiphenyl Dichloroethylene CTD 1.24E-09 6.06E-05 1.53E-07 1.74E-06 89 303 "ACADM,ACTN1,LRRC7,ALK,DOC2A,AMPD3,DPP10,APAF1,BCL2L2,BID,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CAMK2B,CAMK2G,CD86,CD38,CD81,CDH2,CHGA,DLGAP3,NRXN1,NRXN2,CLU,ABCG2,CLOCK,CREM,DCC,MAGI2,DLG4,CASP8AP2,DPP6,CACNG7,EGFR,ERBB2,ERBB4,CACNG2,RACK1,FOXO3,FOLH1,FYN,GABRA4,GABRB1,GFRA1,PPARGC1A,GJB1,GLS,STMN2,GRIA2,GRIA4,GRIK1,GRIK2,GRIN1,NR3C1,IL1RAPL1,IGF1,KIT,NCF2,NF1,NFE2L2,NRCAM,NTRK2,PDGFRA,ABCB1,MAPK3,RELN,MDGA2,PTCH1,RDX,RET,ROBO1,RXRA,HES6,NLGN1,SLC1A2,SLC1A6,SHANK2,SLIT1,UNC5B,STXBP1,SYP,TF,THRA,TNFRSF1B,TSC2,CADM1" Drug CID000002802 clonazepam Stitch 1.25E-09 6.14E-05 1.55E-07 1.76E-06 36 82 "ABAT,ATP1A3,SGCE,CACNA2D1,CBR1,CCK,PNKD,DBI,ATN1,GPHN,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,LOXL3,KCNQ3,MAOB,CNTN3,FXYD1,PTCH1,ASIC4,ARX,SLC4A3,ARHGEF9,ZEB1,ZNF384,EPM2A" Drug CID000008146 DE gel Stitch 1.29E-09 6.30E-05 1.56E-07 1.78E-06 52 143 "SLC12A5,ADORA1,BSN,CACNA1D,CACNA2D1,CACNB2,CSF2RA,DBN1,DLG4,ACOT8,ACTL6B,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HES5,NOS1,GPSM2,POU3F4,ENOX1,SALL1,NLGN1,TET1,JMJD6,SYP,TAC1,TACR1,ACTR6,NR2E1,PORCN,PRDM2" Drug 3800_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "ADD2,ADORA3,GAS7,LGR5,ARHGDIG,ATP6V0A1,RGS9,CACNA1G,KALRN,USP2,LY86,ABCG1,RGS6,ARHGEF10,RIPOR2,INTS1,SMG7,DLG4,DMPK,DNAH9,TRAPPC9,ABCC9,CAMSAP1,AFF2,FOLR2,PRELID3A,B3GAT1,GFER,GRM8,WIF1,IRAK3,ATXN2L,HLF,VSIG4,ICA1,VWA5A,KITLG,MMP16,MYT1,NCAM1,NDP,NRCAM,NTRK2,NTRK3,P2RX7,PCDH9,GPR85,PPARA,PPP2R2B,GDPD2,ZMAT4,RGS12,CCDC102B,SYNDIG1,FOXRED2,SALL1,CNKSR2,PKNOX2,TMEM151B,PCDHA3,HIF3A,UCHL1,LAT2,SEMA3B,MVB12B" Drug 3524_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "SLC12A5,ADORA1,ADGRF5,PPFIA4,APLP1,FAM131A,ASTN1,CADM3,LDLRAD4,CACNB4,PLEKHB1,ZFYVE9,TMEM59L,ENTPD4,NCOR2,CSF1R,ZNF804A,C2CD2L,RABGAP1L,PLXNC1,TENM1,ING4,TNK2,RASGRP2,CORO2B,ZNF589,TBR1,FYB1,FYN,ALDH1L1,RUNDC3A,GLYR1,GNAS,AP4S1,GUCY1A2,KCND3,KCNMA1,MN1,ZNF862,MYT1,NUCB1,CDK18,MAPK7,FAM120C,RAB3IL1,SYBU,SLA,PKNOX2,SLC11A1,CXXC4,SMARCD3,LIMCH1,ARHGAP26,DOCK9,ARHGEF12,HEY2,SEZ6L,TRPC1,OSBP2,LMF1,WIPF1,DNALI1,SLC17A7,KCNAB1,EPM2A" Drug 4764_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "ALCAM,APLP1,PPFIA3,PLA2G4C,SLC4A4,CFAP410,CA4,NEURL1,TAOK2,QKI,RCHY1,NCOR2,CSF1R,CNTNAP2,USP6NL,TBC1D5,SMG7,SLC12A6,DRD1,RCAN1,DTNA,EFNB3,EGFR,ING4,DMTN,STX2,ST3GAL6,FGFR1,AFF2,GALC,ALDH1L1,GRB10,CACFD1,GRM8,GUCY1A2,RASSF8,ATXN2L,IL6ST,MEF2C,KITLG,ZNF862,NF1,NPTX1,PDPK1,RETREG1,NLE1,STRN3,LRP12,PPP5C,RAB3IL1,RGS10,SLC1A7,ZNF423,ELOVL4,VAMP1,PLCB1,TBCEL,SZT2,SYNE1,TNS1,TRPC1,HIRA,SPHK2,EVI5,TIGD6" Drug 3040_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "PDE8B,ATP2B3,ADGRB1,RGS11,KSR1,BAIAP3,CA4,THSD7A,KALRN,CAMK2A,LARGE1,CHGB,CHI3L2,CSF1,RGS6,ARHGEF10,CHD5,DZIP3,TOX,MFAP3L,MAGI2,AASS,ELAVL4,APC2,NSG1,DOT1L,GABRA5,SIGLEC8,MYOZ2,MSTN,RUNDC3A,GNAL,PRUNE2,GRK4,GRIK2,GUCY1A1,HPSE2,KCNK1,KIT,LAMA2,SMAD9,MPP2,NRCAM,DDR2,OPRL1,PPP1R1A,RELN,CNNM2,BCAS3,PLPPR1,PTPN13,PTPRB,RGS12,NUDT11,NLGN1,SLC11A1,TACR1,DNAH7,BHLHB9,TRPC3,TRPS1,AMOT,LMF1,ZNF711,DNALI1" Drug 5394_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "TTYH1,ADCY2,ADRA1D,SEMA6A,LTBP4,APOC1,RASL11B,ATP2B2,SLC2A11,ST3GAL5,CACNA1I,CACNA1G,CFAP410,CACNA1D,CAMK2B,CAMK2G,CBFA2T2,PCYT1B,COL9A3,CSF1,ARHGEF4,CTIF,ELAVL4,VPS13B,EFS,DLL3,TBR1,FYB1,GLS,PCLO,GSTM5,C2orf72,ITIH2,KCNMA1,LIG4,SMAD1,MID1,AFF1,MSR1,NNAT,NOVA2,PFKFB2,SERPINE2,MAPK7,MAPK8,C1orf54,ZFHX4,RPS6KA2,CPEB3,ABLIM3,SMARCD3,ZHX3,NMNAT2,ZNF423,SAMSN1,RGL1,VAMP1,TACR1,IQCE,ZEB1,DOCK9,LAT2,SPHK2,KCNAB1,SSPN" Drug 2674_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "MTUS1,ALK,BIN1,OGT,APBB2,ALDH4A1,SLC2A11,B3GALT2,CADM3,AZGP1,BMP7,MYRF,MAP7,NRXN2,DNAJB5,RAB26,SUSD5,DZIP3,PPP1R16B,ZNF337,RIMS3,DGKG,DNAJC6,MAMLD1,E2F5,MBNL2,ABI2,LPAR6,LRRC23,FABP7,FHL1,PDLIM5,GABRA2,GAD2,SIGLEC8,MYOZ2,GCNT2,GNAL,STON1,HPSE2,KCND3,MEF2C,AFDN,NCAM1,PCDH9,PMP22,MAPK10,PROX1,CNNM2,CCDC102B,SLC9A5,CXXC4,SOX15,ZC3H13,SPTAN1,STXBP1,TRIM2,TGFBR3,TIAM1,DAAM2,TPM1,TRO,PLPPR2,MAP3K12,EVI5" Drug 5519_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "ABHD6,ADRA1D,KIDINS220,NME5,AK2,ALK,BIN1,CDC42BPA,APBA2,SEMA4G,PLA2G4C,ATP6V0A1,KALRN,SLIT2,CLCN4,TPP1,CNR1,CNTFR,CNTN1,AKAP7,CSF1,SUSD5,EDRF1,ZNF337,RASSF2,TBC1D5,SPOCK2,C2CD2L,SGSM2,DSCAM,DTNA,ST8SIA3,FHL1,TPK1,CAMKK2,GAD2,LYVE1,POLL,GPM6B,GUCY1A2,C2orf72,INPP5B,KCNH2,SAMD14,MYL3,NUCB1,PACSIN1,ZSCAN32,ROBO1,RPS20,RASA3,ANKRD6,COA1,SNCA,ZCCHC24,EMC1,IQSEC2,PHLDB1,STX1A,ROBO3,TK2,MICAL1,ZNF711,MAP3K12,SEMA3B" Drug 4602_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "DPF1,SLC12A5,ADORA2A,C1QTNF3,AMPH,ANK1,PPP4R4,ASCL1,AZGP1,BAIAP3,CACNA2D1,CRLF1,RAB26,NRG2,CSF1,ARHGEF10,CTNND2,TOX,SMG7,SNX29,ELN,APC2,SEMA6C,GABRA3,SIGLEC8,MYOZ2,NEU3,GPR75,POLL,GRIK5,GRM1,VSIG4,KCND3,SMAD1,MYCN,NOS1,PDGFRA,PIK3R1,RETREG1,NLE1,ST8SIA5,SNRK,PTH1R,ELOVL2,RTN1,SELL,MRAS,SLC1A6,SLCO1A2,SNCA,ARHGAP26,CDK19,NPAS3,ATP10B,ELOVL4,ARC,PCDHGA1,RALYL,PCDHA5,TEK,SLC44A1,RUNDC3B,KCNK12,SLC30A4,PRDM2" Drug 5088_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "ACHE,ADORA1,KIDINS220,BBOX1,TRMT9B,APLP1,ARHGDIG,DNAH17,SLC4A4,N4BP2L1,RGS11,HAP1,BRSK2,ENTPD2,DLGAP1,FOXN3,PICK1,WHRN,CSF1,RGS6,MFAP3L,DRP2,DSCAM,ABCC9,EDNRA,SRPK3,PIPOX,CEND1,SCARA3,AGAP2,SORBS1,FYB1,GABRA5,SIGLEC8,GLI2,GPM6B,GRM1,PTGDR2,ICA1,ITIH2,KCNF1,KCNMA1,KIT,MBNL1,AFF1,ZNF862,NF1,PMP2,MASP1,SNRK,PTH1R,RGR,PAQR6,SEMA6D,SLA,SLC4A3,KDM4B,SOX10,KDM4C,MAPK8IP3,TAL1,KIAA1107,SZT2,TK2,TMOD1" Drug 3316_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "NDRG2,APLP1,CDC14B,DNAH17,PTCH2,CFLAR,CAMK2B,CBFA2T2,NEURL1,EPS15L1,RAB33A,STOML1,SULT4A1,LY86,PICK1,CSF1,MAGI2,DRD1,USH1C,EFNB3,EN2,F5,ZNF589,FGF12,FGFR1,AGAP2,TRAF3IP2,GAD2,ALDH1L1,ADAMTS13,CD200,MYH7,ZNF862,NEUROD1,SNTG1,PIK3CD,PPARA,PPP2R2B,GRAMD1C,ELOVL2,PTPRD,CRTAC1,MYH14,KIRREL1,ASAP3,SLC1A7,RIMS1,ARHGAP26,ATP10B,INKA2,AJAP1,SYT5,ROBO3,ARHGEF12,HEY2,CABIN1,PIK3R5,TRIO,TRPC1,TRPM2,KCNK12,XRCC4,DNALI1,SLC17A7,NUP214" Drug 2174_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "DPF1,MTUS1,CDC42BPA,APC,SEMA4G,PRX,DNAH17,CADM3,MPDZ,CFAP410,SYNGR3,ABCG1,AATK,VCAN,RIMS2,CTIF,CDON,DTNB,MBNL2,EGR3,TUBB4A,BAIAP2,AGAP2,TACC2,GPR153,CSDC2,RUNDC3A,ZNF276,GNAO1,STON1,SPACA9,GRM1,GRM7,GSN,AP4S1,KCND1,KCNH1,MAP4,MBP,MMP16,ADAM22,SAMD14,NNAT,ENPP2,PFKFB2,PLCD1,SLC25A23,MAPK7,GRAMD1C,WDR25,FAM120C,NKAIN1,ZMAT4,RGS4,RGS12,FRMPD1,CCDC92,SLN,LHPP,KCTD2,VIPR2,LMF1,XRCC4,KCNAB1,NUP214" Drug 2305_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "NDRG2,FAM135A,TRMT9B,CDC42BPA,SPTBN4,DNAH17,ASPH,ATP6V0A1,BACH1,NRP2,CALB2,CAMK2B,CAMK2G,CDH2,CACNA2D2,CHRNB2,CLCN3,FADS2,AATK,RABGAP1L,EFNB3,LRRC17,NRN1,OLFM1,FGFR1,GFAP,GRM8,CELF3,IRAK3,C2orf72,KCNB1,KCND1,L1CAM,MDM4,MN1,NPTX2,OGG1,PDE4A,SERPINE2,PLCD1,PDZRN4,TNPO2,RELN,PTAFR,CCDC40,RASGRF1,SEC61A2,SBF1,ASAP3,SLC6A9,LIMCH1,SNCA,SOX10,HECW1,SPTB,ZBTB43,TROVE2,MAPK8IP3,KAZN,TNS1,SEZ6L,CLIP2,SLC13A3,DNALI1,NUP214" Drug 3209_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "ADD2,APC,PDXK,CDK13,PDE8B,ATP2B2,MYRF,BTRC,CFAP410,KALRN,DGKI,CDH8,FOXN3,PLAA,WHRN,BAG4,CNTNAP2,DCAF8,TOX,CTIF,ARMCX2,HEPH,TRAPPC9,DTNB,EFNB3,TNK2,ELAVL4,FABP7,FHL1,GABRA1,GRM1,SYNPO,AFDN,NOVA2,NTRK2,CDK14,POU6F1,LRRN3,RIPOR1,RGS12,KCTD17,TCP11L1,SLC6A8,ARHGEF40,SLCO1A2,SMARCC2,SNCA,KIF13A,DOK5,ZSWIM8,ARHGAP26,RBM26,LHPP,ATP10B,SYN2,TAC3,TACR1,EXOC7,DOCK9,OBSL1,VAV2,LAT2,KCNK12,WNK1,PHTF2" Drug 4555_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.31E-09 6.44E-05 1.56E-07 1.78E-06 65 197 "AMT,ANK1,EPB41L5,APOC1,PPP4R4,ASTN1,NRP2,CFLAR,BMP7,ST3GAL5,MTMR3,SLC16A4,CBFA2T2,SCARB1,CHRNB2,CSF1,ARHGEF10,IPCEF1,CTNND2,MAGI2,SV2B,DTNA,ST8SIA3,ING4,GAD1,GAD2,RUNDC3A,GPER1,GRM7,GRM8,BACH2,MAN2A2,AFF1,MMP16,NTRK2,ODF2,PDE4D,PDGFRA,ENPP2,EPN1,POLG,MAPK8,PTAFR,RALGDS,RASGRF1,KHDRBS2,TTLL7,KLHL11,TMEM206,SCN8A,RASA3,FAM102A,SLC2A5,TNIK,ZHX3,RBM26,LHPP,SYT11,ARHGEF9,ADGRL3,TRIM2,GPR161,SSBP2,EVI5,KCNAB1" Drug 2523_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.40E-09 6.85E-05 1.66E-07 1.89E-06 64 193 "NDRG2,BIN1,CDC42BPA,APBB2,PPP4R4,PLA2G4C,ALDH4A1,CCDC181,ST3GAL5,HIP1R,ZFYVE9,KIAA1549L,NMT2,FEZ1,CNTNAP2,DZIP3,RIMS3,DNAJC6,GSDME,USH1C,CNNM1,EFNA3,DMTN,TLR7,REEP2,FER,KIAA1109,FGFR3,GAB1,GAD1,SIGLEC8,GNG4,STON1,RAPGEF1,HAS2,PTGDR2,KLF12,KIF5C,VWA5A,MEF2C,FXYD6,NCAM1,PCDH9,PCSK5,PHKG1,CCSER2,GPSM2,SLC25A23,PKIA,FAM184A,MYH14,EMID1,RPS20,PPM1E,ANKRD6,TMCC1,IZUMO4,SPTAN1,SPTB,RGL1,KIAA1107,DOCK9,TEX15,ICAM5" Drug ctd:C009277 sodium arsenate CTD 1.47E-09 7.19E-05 1.74E-07 1.98E-06 360 1719 "RALGAPA1,CLK4,ACTN1,METAP1D,FMNL2,KLHL32,SNX30,MTUS1,AGT,TAOK1,SPARCL1,ALCAM,AMT,OGT,ANK1,LRCH2,ANK3,SEMA7A,APC,USP37,MIER1,ARHGAP5,CHID1,ATM,SLC4A4,ATP2A2,ATP2B1,MYOM1,BACH1,BCHE,FGF17,NRP2,CFLAR,DST,FUBP1,MTMR2,C1QC,SGCE,NIPA1,CACNA2D1,CACNB2,PTBP2,CAMK2D,CAMK2G,CANX,CARS,SPAG9,NFS1,KYAT1,LDB2,KRIT1,USP2,NEURL1,CDC25B,CDH2,ZMYM4,MAGI1,CDO1,CLGN,CFL2,SRSF11,B4GALT6,JAM2,KMT2C,CLCN3,FADS2,ABCG2,DNAJB5,QKI,HECTD1,NIPBL,CNTFR,AKAP6,SLC25A27,COL11A2,SLC4A7,RCHY1,BAG4,IGDCC3,CPS1,CLOCK,RBM39,RNF14,SLC32A1,ANKRD44,NCOR1,MICAL2,CST3,APPL1,UBXN2A,USP6NL,TBC1D5,MATR3,TOMM20,HP1BP3,ZC3H11A,SACS,SPOCK3,RABGAP1L,CHRDL1,DMD,DMPK,NR1D2,CPEB2,SLC12A6,PDCD6IP,DTNA,DYRK1A,ABCC5,ABCC9,GOLT1B,TSPAN5,EEF1A2,HIPK3,FCF1,TMTC1,SH3GLB1,PHF20L1,EGFR,AASS,EIF5,PLEKHA1,ING4,PAN3,DCTN4,HSD17B14,EPB41,LRRC23,LRRC17,MRVI1,REEP2,ACSL4,ATP8A1,FKTN,PRMT5,KAT8,FGFR1,CAP2,FOXM1,SEMA6C,AFF2,FOLR2,NBEA,ZCCHC17,SORBS1,ZBED3,TRIM16,TPK1,ATP6V1H,OGA,FAM184B,ERAP1,GATM,GCK,GFER,GFRA1,PPARGC1A,MALT1,BRD8,GLDC,GLUL,FERMT2,PRUNE2,GPM6B,GPER1,GRIA1,NR3C1,KIF3A,RNF165,BVES,FAM107A,GUCY1A1,HAS2,MAN1B1,HMGB1,HMGCR,HNF4G,AGFG1,HSF2,SMAP1,IGF1,IL6ST,DIPK1A,ITPKB,JAK1,KCNA1,KCNB1,KCND3,KLHL23,KIF5A,KIT,KLC1,STXBP5,LAMA2,LAMP2,LIFR,LIMS1,PAXBP1,ARHGAP12,LSAMP,LSS,MAP2,MAPT,MAT2A,MBNL1,MBP,CHIC1,MEF2C,MKLN1,MN1,SESN3,MTTP,MYCN,NFIA,NFE2L2,NFIX,NNAT,HCN1,DDR2,NUCB1,PAH,TREM2,PBX1,PC,ETFRF1,PDE4B,PDGFRA,PFKFB3,OLA1,PGAM2,PIK3C2A,PIK3R1,CCSER2,SNX10,XRN1,FTO,PLTP,RC3H2,PSAT1,SCHIP1,MINDY2,PPP2R5C,PRKCB,MAPK3,MAPK8,MAPK9,PRPH,PRPSAP2,GDPD1,ANKHD1,PXK,PTPRB,PYGM,RAB5B,USP47,FAT4,RBBP6,BSDC1,RDX,REV3L,MRPS18A,SLC25A36,SETD5,TMEM206,SARS,SEMA6D,ATXN1,ATXN2,SCN7A,FNIP1,SMPD3,SFPQ,HSPA4L,SGK1,SCG5,KIF21A,PPP1R9A,DOCK10,CHD9,DZIP1,PREX2,PPP4R3A,CCDC88A,SLC15A2,SCMH1,BTBD7,CPEB4,ZKSCAN3,RCOR3,RIMS1,KIF13A,TMCC1,FAM126B,PDZRN3,RBM34,SON,TNIK,FNBP1,ENKUR,MYCBP2,ZNF423,KIF1B,NFASC,TROVE2,ITPRID2,LARP4,SS18,ERBIN,ADHFE1,FAM168A,ARC,SYPL1,POPDC3,TACC1,MGRN1,TCF4,SIN3B,DMXL2,ZEB1,TRIM2,TCF12,NSD1,FRYL,TEX15,AP4E1,HHIP,AKTIP,TNR,PIK3R5,TP53BP1,RBFOX2,TPM1,TPM2,TPM3,NR2C2,SYNPO2,TRIO,TRPS1,DCBLD1,TSN,RPL7L1,PDIA2,RICTOR,ETNPPL,ZNF24,SLC38A1,EVI5,ADAMTS9,CIAPIN1,MDH1B,SNX27,WNK2,RGS7BP,AMN1,DOCK8,ST7,RTN4,ACTR3B,JMJD1C,MSRB3" Drug 4304_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-09 7.26E-05 1.75E-07 1.99E-06 63 189 "ADRA1D,TRMT9B,ARRB1,ALDH4A1,ATP1A3,SYNJ1,KALRN,ADGRG1,NRXN3,WHRN,NCOR2,PLCH2,CTNND2,CYBB,DCAF8,CTIF,ATN1,DSCAM,DTNA,DUSP9,SORBS3,LRRC17,GAB1,SIGLEC8,RUNDC3A,GPM6A,GRIK5,SOX21,ATXN2L,KCNMA1,MAOB,NPTX1,NRGN,NUCB1,PALM,GPR85,PKM,FXYD1,LRRN3,PROX1,GDPD2,PEX5,RAB3A,RFX2,RGS4,SEMA6D,ZFP2,MRAS,ZNF334,SLC15A2,SNCA,WDTC1,SP2,ZSWIM8,IQSEC2,DDN,ATP11A,MCF2L,DOCK9,TMOD1,TRO,TRPC1,NDRG4" Drug CID000000197 AdPK Stitch 1.53E-09 7.47E-05 1.80E-07 2.04E-06 329 1548 "ACLY,CLK4,ACTN1,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,CDC7,ADORA1,ADORA2A,ADORA3,KIDINS220,AP1B1,AGT,NME5,AK2,TAOK1,ALK,MAP4K3,MYH7B,APAF1,APC,DGKZ,DGKD,CDK10,PDXK,CASK,ARRB1,CDK13,STK33,MARK4,DYNLL1,ATM,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,ATP6V0A1,RIPK1,KIF1A,FGF17,BMPR1B,BTK,AP1M1,DDR1,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CCNH,P2RX6,CD38,ENTPD2,DGKI,CDK11B,CDC25B,CDC27,DCLK1,ASIC3,TAOK2,ZFYVE9,MYL6B,CLTA,CLTC,CNTN1,CPS1,ABCG1,CS,CSF1R,CSF3R,CSNK1E,CSNK1G3,ZFYVE16,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DCTN1,AK5,DMD,DMPK,GNE,DYRK1A,DNM1L,ABCC9,E2F5,EDN1,SGK2,HIPK3,EGFR,EIF4G1,EIF5,IRAK4,TNK2,ENO2,DMTN,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,KATNAL1,F3,F5,F8,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,STRADA,TESK2,PPP1R1B,FER,FGF1,ACTL6B,FGFR1,FGFR3,FGR,PRKAG2,ATP5PD,IP6K2,VTI1B,FOXO3,FLT1,DCTN2,AK8,TPK1,ARFGAP2,CAMKK2,ATP6V1H,ATP2C1,CELF1,BRSK1,FYN,GAB1,CAB39,JPH4,NEK6,IP6K3,IQGAP2,MTHFD2,ACSS1,GART,GCK,GGT7,GGT5,MALT1,GK,TTBK1,DBF4,GLS,GLUL,DCLK2,GNAS,GPD2,LPAR4,TUBA1C,RAPGEF1,CIT,GSN,MAP4K5,IRAK3,DDX19B,HMGCR,HSP90AA1,MYLK2,IL11RA,TUBB2B,ITGAM,ITPKA,ITPKB,JAK1,JAK2,KHK,KIF5A,KIT,SMAD1,MARK1,MARK3,MAT2A,MATK,MEF2C,AFDN,STK32C,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,P2RY13,NDUFA5,NEK1,NEUROD1,NME4,NRGN,NTRK2,NTRK3,DDR2,KSR2,NUMA1,OGDH,P2RX7,P2RY1,PAH,PAK3,PC,CDK18,PDE3B,PDE4B,PDE4D,PDGFRA,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,ABCB1,PHKG1,PIK3C2A,PIK3CD,PIK3R1,ZNF655,PKM,PLCB2,PLIN1,PMS2,POLR2F,PTPA,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,PRKCG,PKN2,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRPSAP2,SNRK,PTK2,RAB3A,ACSS3,RAD17,RET,RNASE1,MYH14,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,RPS20,HUNK,MAPK12,CASC3,SGK1,MYO18A,SLCO1A2,MAST1,WDTC1,TNIK,KIF21B,FNBP1,NMNAT2,PEG10,CDK19,SRPK2,MAPK8IP3,NEK4,TTBK2,ABCC8,SYT1,ATP11A,TAF6,MLST8,TAF9,CLASP1,TEK,TIE1,TK2,ACTR6,TLR4,TMOD1,TNNT1,CABIN1,TPM1,CDK20,NPL,TPM2,TPM3,TPM4,TSC1,TSC2,SGK3,TUBB1,UBC,P2RY12,RICTOR,SPHK2,WNK1,MAP3K12,TUBA1A,WNK3,WNK2,PAK5,CAMK1G" Drug 1637_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.57E-09 7.67E-05 1.84E-07 2.09E-06 62 185 "ADD3,NME5,ALCAM,MARK4,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,ARHGEF10,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,GNE,TSPAN5,OPTN,EFNA3,EFNB3,DPYSL4,FYN,GLS,RAB40B,STON1,GPR37,RNFT2,PADI2,KIF5C,MITF,MXI1,NEK1,SERPINE2,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,LRRC49,PTCH1,SH3BGR,SH3GL3,PPM1E,ASAP3,ZNF365,KDM4B,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,ZNF45,REEP1,NAV2,SLC17A7" Drug 5822_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.65E-09 8.09E-05 1.88E-07 2.14E-06 61 181 "ABAT,ABHD6,ADRB2,NME5,CDC14B,ARNTL,ST3GAL5,HIP1R,REPS2,CHN2,CLU,ABCG1,VCAN,CTH,DNAJC6,C2CD2L,PLPPR4,EFNA3,FAM13A,MRNIP,RGS17,TAOK3,TESK2,SEMA4D,DPYSL4,FYN,GLS,GUCY1B1,DIPK1A,KCNF1,KIF5C,LIFR,MAPT,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINE2,SERPINI1,RETREG1,PRPH,PID1,RGS4,FBXW7,SH3GL3,ASAP3,FAM214B,ELMO2,PALLD,ZCCHC24,BEX1,ARHGAP26,THSD1,ELOVL4,RGL1,SYT11,VAMP1,SYT1,UBE2H,DNAJC12,TRIM9" Drug 4374_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ACTN2,ADORA1,KIDINS220,LTBP4,ANK1,CDC14B,ATP2B2,CACNA1D,CAMK2B,GPR37L1,RAB33A,TMEM59L,SULT4A1,ARHGEF4,NOS1AP,SNPH,INTS1,DNAJC6,DNAH9,SGK2,HSD17B14,F5,REEP2,FABP7,DLL3,GABRG2,SIGLEC8,GFER,RUNDC3A,GLI2,GNG4,GRIK2,GRM1,GRM2,GRM8,PTGDR2,IFI16,KCND3,KCNH2,MAG,AFDN,MN1,TAGLN3,MYCN,MYT1,NCAM1,NNAT,RFX2,CARF,EMID1,CNKSR2,DZIP1,IZUMO4,HECW1,CDK19,MAPK8IP3,TACR1,TCF4,ICAM5,R3HDM1,UGT8,LAMP5,DNALI1,PLSCR4,TIGD6" Drug 4375_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "AGT,TRMT9B,FGD2,ASPH,N4BP2L1,AZGP1,SCAPER,CFAP410,KRIT1,CHI3L2,CHN2,QKI,CNTN1,DGKG,SPOCK2,ATN1,DTNA,EDNRA,AASS,ING4,KCNMB2,FOXG1,GCNT2,GPM6B,GRM7,GUCY1A2,HRH3,KLF12,KCNJ5,KCNN1,MGAT3,ADAM22,TAGLN3,MYBPC1,NCAM1,OPCML,PFKFB2,PIK3CD,POU3F4,CEP41,CNTLN,PTHLH,RAD52,RGS4,EMID1,SH3BP2,CPEB3,SLC6A11,CCDC88A,CXXC4,KIF21B,SPART,AJAP1,FAM168A,PLCB1,TBCEL,DOCK9,PCDHA5,RIMBP2,TPM2,VIPR2,SLC30A3,STMN4,KCNAB1,MVB12B" Drug 5495_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "AGT,KIAA1324,PLA2G6,TRMT9B,ASTN1,ATP2A2,N4BP2L1,LDLRAD4,CAMK2B,CD86,CACNA2D2,ABI3BP,CSF1R,MICAL2,PDE4DIP,CNTNAP2,BRINP1,GIT2,MED12,DYRK1A,SGK2,MBNL2,EN2,FGFR1,BAIAP2,CAMKK2,DISC1,CNTRL,GRIN1,CACFD1,GUCY1B1,PADI2,DHX35,IL6ST,KCNB1,KHK,LIG4,SMAD1,MAN2A2,SETD4,PDE3B,STRN3,PACSIN1,PPARA,RALGDS,MYH14,ZNF821,SLC6A9,BTBD7,ZKSCAN3,COA1,TNIK,PEG10,CLSTN2,THSD1,TAC3,ROBO3,TBL1X,KIAA0930,RPGRIP1L,TRPM2,MICAL1,EVI5,SLC17A7,KCNAB1" Drug 6611_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "KIDINS220,LTBP4,SEMA7A,KCNAB2,APC,EPB41L5,GAS7,MPDZ,BMPR1B,BTRC,KALRN,CAMK2B,RUNX1T1,CDH8,CACNA2D2,ARHGAP22,DNAJB5,CRY2,FEZ1,VCAN,RIMS3,ARNT2,DLG3,EDIL3,SNX29,HIPK3,ERCC2,FGFR1,FOXG1,FOLR2,ALDH1L1,RND1,GNG4,GRIK1,ICA1,IGFBP1,KCNJ5,KIFC3,VWA5A,NPR2,OMG,GPR85,PFKFB4,SPATA6,POU6F1,PPARA,WDR25,TMEM231,CARF,SYNDIG1,IL17RB,SELL,SHANK2,DOK5,BEX1,SPTB,CDK19,NPAS3,SPART,COBL,MCF2L,TBCEL,RUNDC3B,AMACR,KCNAB1" Drug 2649_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "SYN3,ADGRF5,TRMT9B,SEMA4G,RGS20,PLA2G4C,ASCL1,ALDH4A1,ATP6V0A1,RGS11,ARHGAP33,SLIT2,FAM149A,RCHY1,PLCH2,RIMS2,DBT,TMCC2,TRAPPC9,DTNB,SIDT2,EFNB3,HSD17B14,RASGRP2,NCALD,NRN1,DLC1,ZNF589,KIAA1109,OLFM1,FGFR1,GABRA2,TRAF3IP2,ALDH1L1,GCNT2,AHDC1,USP19,C1QL1,GNAL,GNAO1,GRB10,ATXN2L,ICA1,KCNJ5,KCNMA1,MDFI,NPTX1,PIK3CD,NLE1,MBOAT7,PPP5C,MAPK8,PRPH,PTN,CCDC40,RGS12,GSTCD,MAPK8IP3,RGL1,TLR4,SEZ6L,VLDLR,DNALI1,GDPD5,ADAMTSL3" Drug 7365_UP Riluzole hydrochloride; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ABHD6,CDC42BPA,KCNAB2,EPB41L5,SHROOM2,MADD,C5,BTRC,PTBP2,SOCS6,QKI,WHRN,AATK,PARD6A,SPOCK3,CHRDL1,EXOG,DPH1,HIPK3,FCF1,PLXNC1,ELN,COQ7,ETV1,RRAGB,TESK2,FGF1,FGF13,TRMO,GLI2,GLRB,CNTRL,IL6ST,IL11RA,LMO2,TM6SF1,TAGLN3,NDP,NOS1,CLDN11,TMEM104,PLPPR1,PTHLH,PTPRN2,RGS4,ARHGEF10L,MYH14,TRAPPC13,FBXO11,ST6GAL1,ANKRD6,WDR37,TNIK,KDM4C,ST5,PHLDB1,PLCB1,AHCYL2,ZNF34,R3HDM1,ZKSCAN5,XRCC4,KCNAB1,EPM2A,DPF3" Drug 6750_UP Hesperetin [520-33-2]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "NR0B1,DDO,AQP4,ADGRB2,CFAP410,CAMK2B,CDC42,KCNAB3,CACNA2D2,CHN2,CABP1,ABCG1,PDE4DIP,FAM131B,TOX,INTS1,DAPK3,SRGAP3,DRP2,EDN3,EDNRB,ELAVL3,NCALD,EFS,F5,ZMYND10,FGFR1,CAMSAP1,FOXG1,ALDH1L1,SRCAP,TOX3,GNAL,GPR17,GRIK1,PTPRT,HNF4G,KCND3,ADAM11,ADAM22,NEFM,NNAT,GPR88,OLR1,PBX1,PDE4D,GPR85,PRKCB,PTH1R,ENOX1,FEZF2,SLA,PREX2,SLC11A1,ZC3H13,DDN,PCDHGB6,FAM189A1,TPM2,RPRM,VLDLR,EMSY,NT5M,SEMA3B,KCNAB1" Drug 5095_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "AGT,TRMT9B,PKP4,APBB2,APOC1,PPP4R4,PDE8B,SLC4A4,N4BP2L1,BAIAP3,CFAP410,CACNG1,MAGI1,CHRNB2,PICK1,RIMS2,RIMS3,CTIF,DRP2,COQ7,MTSS1L,CDKL3,DLC1,FGFR1,AGAP2,EFCAB2,SORBS1,CAMKK2,SIGLEC8,SRCAP,RUNDC3A,GNAO1,GPM6B,GRM8,IL1RAPL1,ITGA7,KCNMA1,P2RX7,PDE3B,PDGFRA,GPR85,PLCD1,TNPO2,PTPRN2,FAM120C,TMEM231,CCDC40,C1orf54,GAL3ST4,RNASEL,RYR1,SLC8A2,DOK5,ZBTB43,CEP68,SYT5,CRTC1,PCDHA5,AP4E1,ZNF34,TK2,TPM3,TRIO,TRO,VIPR2" Drug 2725_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ACTN2,FGD2,APBB2,PLA2G4C,ADGRB1,CACNA1G,LDLRAD4,BTRC,CAMK2B,NEURL1,VAX2,DNAJB5,SULT4A1,CRY2,ABCG1,CRYM,DZIP3,DCAF4,EDRF1,SPOCK2,KLHL3,TMCC2,MAMLD1,PLXNC1,OLIG2,VPS13B,RASGRP2,TUBB4A,DLC1,FGFR1,BAIAP2,GALC,ADAM28,SPACA9,GRM7,HRH3,TJAP1,KIT,SCAMP5,MYO7A,NAP1L2,OMG,OPCML,OPRL1,PFKFB4,PLCD1,CEP41,VPS13C,SYNDIG1,ST6GAL1,SLC1A2,SHANK2,RIMS1,KIF13A,SOX15,CAND2,SYNE2,TEX15,TF,CHST8,TGFBR3,PRMT8,KLC2,ZBTB38,SLC30A3" Drug 2715_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ADD2,AP2A2,ALK,BEGAIN,BIN1,CDC42BPA,PRX,DDX3Y,BMP7,SGCE,CFAP410,CACNA2D1,CDO1,ABCG2,QKI,CRY2,AATK,EDRF1,RIMS3,DAPK3,DBT,CNIH3,KLHL3,SV2B,DLG3,EXOG,DUSP9,EFNA3,PLXNC1,OLIG2,DMTN,OLFM1,FGFR1,AFF2,PRELID3A,CPLX2,NXPH3,ICA1,IL12A,KIFC3,BCO1,NEFM,OPRL1,PDE4D,PLCD1,POU3F4,PPP2R2B,CEP41,VPS13C,PTPRN2,TTLL7,MYH14,MAP6D1,RPS20,SYNDIG1,SLC1A3,PHLDB1,PSD3,TGFBR3,TMOD1,PRMT8,TRPC1,SPHK2,SLC17A6,FZD3" Drug 3612_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "SPARCL1,MRTFA,APC,AQP6,MARK4,PTCH2,ATP2B2,ST3GAL5,GYG2,BTRC,INA,CDC42,CDH2,RCBTB2,ZFYVE9,CSF1,VCAN,RIMS2,CTIF,SRGAP3,HS3ST2,EDN1,SGK2,OLIG2,ETV1,KIAA1109,AFF2,FOLR2,GPR153,NSG1,GAD2,RND1,GRM8,PTGDR2,ITGA7,KCNN1,KIF5A,MEF2C,MGAT3,CD200,ZNF862,NEUROD1,NPR2,NECAB2,POU3F2,CEP41,PTAFR,ELOVL2,C1orf54,TTLL7,RNASE1,RXRA,SLC1A3,MYH15,SNAP25,SOX10,PEG10,ACSBG1,SYN2,SLC44A1,HEY2,TTPA,MKRN3,SPHK2,CA10" Drug 4179_UP Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "SYN3,TKTL1,ALK,ATP1A2,SLC4A4,ATP2B2,ADAM23,BACH1,CACNA1G,BAIAP3,CACNA1A,KALRN,CBFA2T2,CHI3L2,CHRNA4,CLCN4,FAM149A,ARHGEF10,BRINP1,KLHL3,SPOCK3,EDNRA,EN2,KIAA1109,FHL1,FLNC,DCTN2,GABRA2,ZNF44,SEPT9,GNAL,GRM8,GUCY1A2,IRAK3,HLF,SCRG1,IGF1,KCNC1,KCND3,KCNMA1,MID1,MOBP,MYO7A,NCAM1,NOVA2,PDE4A,GPR85,PLXNB1,PPARA,SAMD9,PTPRB,RAD52,KHDRBS2,RNASE1,SATB1,FRMPD1,MAPK8IP3,ACSBG1,TACR1,TEK,ZFPM2,CHST5,TRPC3,VSNL1,WIPF1" Drug 3984_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ACTN2,NDRG2,ADD2,SLC12A5,SEMA7A,PKP4,CDC14B,CDK10,ADAM23,ADAM15,CFLAR,MTMR3,BAIAP3,MAP7,LDB2,CBFA2T2,CNTFR,AKAP7,WHRN,AKAP5,IFFO1,TCEAL2,PDE4DIP,EDRF1,SRGAP3,ATN1,DYRK1A,EDNRA,HIPK3,NRN1,HPCAL4,TRMO,OGA,SRCAP,RND1,STON1,MCHR1,IL12A,KCNN1,DUSP26,PILRA,SUSD4,STK32B,DOCK10,FUZ,PEX26,SLC11A1,ZNF334,ZHX3,SMG6,SZT2,PCDHGA1,CHST8,GPR161,SLC44A1,R3HDM1,TPM1,HIRA,TUBB1,VGF,VIPR2,LAT2,WNK1,NT5M,PHTF2" Drug 6175_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.66E-09 8.13E-05 1.88E-07 2.14E-06 65 198 "ACTN2,ADRA1D,NR0B1,CNTNAP1,APC,CDC14B,SLC4A4,ALDH7A1,CACNA1I,CA4,TAOK2,TMEM59L,CNN3,CNR1,CSNK1E,SIPA1L1,PARD6A,SV2B,TMCC2,DLG3,CDON,ATN1,USH1C,EFNB3,MRNIP,HSD17B14,OLFM1,GPR153,SIGLEC8,GPR162,CSDC2,ZNF276,GPD1,PTGDR2,KCNJ9,MSR1,NPR2,OXTR,GRAMD1C,CNNM2,GDPD2,PTPRN2,RASGRF1,GAL3ST4,MORC4,RGS12,SYNDIG1,KCNIP1,RYR1,SEMA6D,SH3BGR,ASAP3,SOX2,ZC3H13,NPAS3,NFASC,PSD3,SLC35G2,ICAM5,TUB,TUBB1,LMF1,VSNL1,KCNK12,KCNAB1" Drug CID000004624 6-OHDA Stitch 1.71E-09 8.37E-05 1.93E-07 2.20E-06 78 255 "ACHE,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,PRX,BSN,CALB1,CALB2,CCK,CHRM1,DRD1,DYRK1A,DNM1L,EEF1A2,PPP1R1B,GAD1,GAD2,ARPP21,GFAP,GFRA1,LOXL3,MCHR1,GPR37,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM8,HRH3,HTR2A,IL12A,PACRG,MAOB,MAPT,NPY,OPA1,OPRL1,PDE4B,PDYN,PENK,MAPK3,MAPK4,MAPK7,MAPK9,MAPK10,KLK6,RET,FBXW7,MAPK12,HSPA4L,SLC1A2,SIRT2,SNCB,SNCA,SST,SSTR1,SSTR2,SYN1,SYN2,TAC1,MLST8,ZMAT3,TK2,TRH,UBC,PORCN,SLC30A4,SLC17A7,SLC17A6" Drug 4665_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.73E-09 8.50E-05 1.95E-07 2.22E-06 60 177 "DPF1,ABAT,ABHD6,ADRB2,EPB41L5,ARNTL,MARK4,BRINP2,ST3GAL5,USP2,COL9A3,ABCG1,PDE4DIP,CTH,KIAA0513,RIMS3,DNAJC6,PLPPR4,SRGAP3,EFNA3,RGS17,TUBB4A,TAOK3,TESK2,BAIAP2,FYN,RND1,STON1,SPACA9,GUCY1B1,BACH2,DIPK1A,ITGA7,KIF5C,KITLG,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINI1,PRPH,SYTL2,ENOX1,RGS4,FBXW7,SH3GL3,KDM4B,DOP1A,TNIK,SPTAN1,THSD1,ELOVL4,RGL1,SYT11,VAMP1,SYT1,COBL,HIRA,DNAJC12,PLSCR4" Drug 5745_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.73E-09 8.50E-05 1.95E-07 2.22E-06 60 177 "ABAT,ADRB2,ARNTL,MARK4,ALDH4A1,ADGRB2,ST3GAL5,HAP1,USP2,SYNGR3,NRXN3,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,PLPPR4,EFNA3,RGS17,IGSF6,TAOK3,FGFR1,BAIAP2,SORBS1,FYN,RND1,GLS,STON1,DIPK1A,ITGA7,KCNK2,KIF5C,MAPT,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINI1,PIK3CD,PRPH,RGS4,SH3GL3,KDM4B,SOX15,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT11,SYT1,COBL,MCF2L,OBSL1,SSBP2,DNAJC12,TRIM9,SLC30A3,SLC17A7,PLSCR4" Drug 3395_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.73E-09 8.50E-05 1.95E-07 2.22E-06 60 177 "ADD3,NME5,ALCAM,MARK4,ST3GAL5,BAIAP3,CLGN,WHRN,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TMCC2,TSPAN5,EFNA3,EFNB3,FAM13A,AASS,RASGRP2,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,KCNB1,KIF5C,NAP1L3,NEK1,PCDH9,TMOD2,SERPINE2,SERPINI1,PIK3CD,PRPH,PTPRH,RAB3A,NUDT11,RPS6KA2,SH3GL3,PPM1E,ASAP3,PKNOX2,TNIK,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,ZEB1,HEY1,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 3345_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-09 8.66E-05 1.97E-07 2.25E-06 64 194 "BRAP,BIN1,CDC42BPA,CDK13,DNAH17,ATM,ATP6V0A1,CACNB2,CHN2,CHRNB2,FHL5,CRMP1,PDE4DIP,GPRASP1,CNIH3,TMCC2,DYRK1A,ST8SIA3,MTSS1L,SPEG,FAM198B,ATP8A1,ZNF589,FGF12,AGAP2,FLNC,DLL3,GAB1,TMEM8B,PCDH17,GLYR1,GPD2,GPR22,GPER1,GSN,KLF12,ITGAM,KCND3,MAN2A2,MAPT,KITLG,NEUROD1,NF1,PDE3B,STRN3,CEP41,RAD52,KLHDC8A,ROBO1,RPS6KA2,WLS,MRAS,FRMPD1,SLC1A3,SLC15A2,BTBD7,SLN,COA1,LIMCH1,RIMS1,HIF3A,TMOD1,SPHK2,PRDM2" Drug 2546_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-09 8.66E-05 1.97E-07 2.25E-06 64 194 "CDC42BPA,ANK3,ATP1A3,MYOM1,BAIAP3,SLC16A4,CHRNA4,NRXN2,VAX2,DNAJB5,RAB26,ABI3BP,RGS6,DZIP3,ARHGEF4,BRINP1,TMCC2,DRD1,EDN3,AASS,APC2,CEND1,EYA1,ATP8A1,KIAA1109,AFF2,SORBS1,TBR1,SIGLEC8,SEPT9,MYOZ2,GATM,LYVE1,TOX3,GNG4,GRIK2,AP4S1,PADI2,KCNJ5,KCNJ10,ADAM22,KCNK10,PBX1,PPP1R1A,PRKCG,RGS12,SUGCT,SCN2B,ZFP2,CCDC92,SLC11A1,ZNF415,PALLD,PEG10,SYT5,PCDHGB6,PCDHGA10,PHF24,SLC19A3,SPX,TK2,TNS1,WNT7A,JPH3" Drug 2825_UP Probenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-09 8.66E-05 1.97E-07 2.25E-06 64 194 "ARID1A,ADCY6,AP2A2,NME5,C1QTNF3,SEMA6A,AMT,KCNAB2,APBB2,APC,CDC14B,MARK4,ATM,CFLAR,GYG2,LDLRAD4,SYNGR3,RCBTB2,FOXN3,SOCS6,CTH,EXOG,ATN1,GNE,ABCC9,HIPK3,MBNL2,TNK2,EZH1,KIAA1109,FGF13,AFF2,GAB1,MSL3,GPER1,SPACA9,GRM1,GSN,IRF8,MAOB,MEIS2,MID1,MITF,ADAM22,BCO1,NNAT,PCDH9,MAPK10,VPS13C,ASAP3,SLC20A2,SLN,SNCA,SP4,ZBTB43,MAPK8IP3,PSD3,PCDHA6,ZMYND8,UCHL1,PLPPR2,GDPD5,UBE3B,ADAMTSL3" Drug 2721_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.88E-09 9.21E-05 2.09E-07 2.38E-06 63 190 "NDRG2,ADD2,ALK,BEGAIN,AMPH,BIN1,APBB2,MARK4,BCL2L2,SGCE,CACNA2D1,CDO1,CHN2,TAOK2,LHX2,RAB26,CABP1,ABCG1,KIAA0513,RIMS3,DNAJC6,GSDME,MAMLD1,FAM13A,LRRC23,RASGRP2,ETV1,TBC1D16,GABRA4,SIGLEC8,INPP5K,ADAM28,KCNMB4,STON1,PCLO,IFI16,DIPK1A,ITGA7,KIF5C,MEF2C,NCAM1,SERPINI1,PLCD1,PMP22,MAPK7,CNNM2,TMEM255A,MYH14,WLS,SNCA,TNIK,HECW1,RGL1,STXBP1,DNMBP,ATP13A2,TGFBR3,TMOD1,TPM1,SSBP2,KLC2,REEP1,PRDM10" Drug 2202_UP Gossypol [303-45-7]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.99E-09 9.76E-05 2.21E-07 2.52E-06 62 186 "AP2A2,CDC42BPA,APBB2,ATP2B1,CLGN,CHN2,CLCN4,CNTN1,AKAP6,WHRN,SIPA1L1,CTH,RIMS2,RIMS3,CTIF,DSCAM,FAM13A,EGR3,SORBS3,EIF5,PIPOX,REEP2,ST3GAL6,HPCAL4,CAP2,FLT1,FYN,ZNF44,KCND3,MBNL1,NNAT,NPPA,P2RX7,PDGFRA,ENPP2,EPN1,NECAB2,POU6F1,PSD,RPS6KA2,CLIP1,RYR1,ASIC4,ZNF821,PPM1E,RPH3A,EPN2,SMTN,PKNOX2,SLN,SOX10,SPTB,NPAS3,ATP10B,IQCE,PCDHA5,HEY1,FLRT2,FLRT1,BEST1,LMF1,PLSCR4" Drug 3809_DN Ethotoin [86-35-1]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ASPHD1,ADCY2,AMT,ALDH4A1,ATP1A3,NRP2,SCAPER,MTMR3,CACNB2,CBS,SEPT7,ARHGAP33,AKAP7,COL9A2,AKAP5,IFFO1,TCEAL2,EDIL3,HIPK3,CNNM1,ING4,COQ7,NCALD,FGF1,FGFR1,PRELID3A,EML4,CNTRL,GRIK5,ICA1,SHISAL1,SCIN,ITIH2,ITPKA,KCNMA1,KIFC3,KIT,MAP2,MAPT,GIT1,LYRM9,ZNF862,PIK3R1,RETREG1,SPATA6,ELOVL2,PTPRB,ZCWPW1,TTLL7,ROM1,TMEM206,FBXW7,RXRA,NTNG1,ST6GAL1,DZIP1,KDM4B,TSNAXIP1,ZEB1,TNS2,TRIO,TSN,VIPR2,XRCC4,MVB12B" Drug 5920_UP rotenone; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "MTUS1,MRTFA,KCNAB2,GYG2,BAIAP3,BTRC,SYNGR3,MAGI1,CHI3L2,CNOT8,STOML1,TCEAL2,HAPLN1,CSF1R,PDE4DIP,SPOCK2,MFAP3L,RUSC2,SMG7,DLG4,DNM2,DTNB,SGK2,CELSR3,MRNIP,EN2,ST3GAL6,ZMYND10,GNAS,GNG3,LMO1,MAP2,MAPT,ADAM22,MYL3,NF1,NFYA,NPTX1,NTRK2,NUMA1,TREM2,GPR85,SPATA6,CNNM2,RGS4,ARHGEF10L,RNASEL,GSTCD,SLC1A6,SLC1A7,LIMS2,ZNF334,SLN,TMCC1,KDM4B,NPAS3,SYT1,KAZN,TF,TLR4,TRIO,LAMP5,PCBP4,GAN,SENP7" Drug 6690_UP Flucytosine [2022-85-7]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ASPHD1,APAF1,ASTN1,SLC4A4,RGS9,NRP2,KSR1,SCAPER,GYG2,LDLRAD4,CACNG1,KALRN,CANX,MAGI1,CHN2,CLCN4,AKAP5,CSF1R,MICAL2,IPCEF1,VCAN,NOS1AP,DAPK3,CTIF,MFAP3L,C2CD2L,HIPK3,SEMA3D,SIDT2,MBNL2,RASGRP2,EPHA5,ST3GAL6,ZNF589,PDLIM5,SIGLEC8,DISC1,CACFD1,GRM7,GRM8,ATXN2L,ICA1,KCNJ5,MDM4,NEUROD1,NPY,SNTG1,GPR85,PRKCB,MAPK8,PTAFR,ZSCAN32,RNASE1,MYH14,TCP11L1,PKNOX2,SOX3,IZUMO4,INKA2,ARHGEF9,PCDHA5,AP4E1,TMOD1,SEZ6L,FAM13C" Drug 5954_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "RALGAPA1,ABR,ASIC2,AP2A2,NME5,AK2,AMH,SEMA7A,APOC1,CDC14B,PLA2G4C,DNAH17,SLC4A4,ATP2B3,ATP6V0A1,NEURL1,CDH18,ZFYVE9,TPP1,CHD1L,NOS1AP,RIMS3,DAPK3,JAKMIP2,TMCC2,IGSF6,ACSL4,FOXG1,KHDRBS3,GPER1,SPACA9,GRIN1,GRM2,INPP5B,KCND3,KCNN1,MATK,MMP16,ADAM22,MX1,MYO7A,NNAT,P2RY1,PCDH9,RETREG1,NECAB2,MAPK10,PTHLH,GSTCD,SLC11A1,EMC1,SPTB,IQSEC2,NSFL1C,FAM189A1,PSD3,TF,THRA,TMPO,RBFOX2,RUNDC3B,VAV2,SPHK2,NT5M,NUP214" Drug 6024_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ABHD6,AMPD3,AMT,ARSE,ADGRB3,RGS11,NRP2,CACNA1A,CACNA2D1,HAP1,CAMK2B,CDO1,CHRNA4,CNN3,NRG2,DGKG,ELMO1,ATN1,DUSP9,KCNMB2,SPEG,F5,GAB1,ADAM28,RUNDC3A,GNAL,GNAO1,PRUNE2,GPR22,GRK4,GRIN1,GRM8,ITGA7,KIF5A,NEFM,NPPA,PFKFB2,LRP12,POU3F4,PPARA,PPP5C,PTHLH,FAT4,KHDRBS2,RFX2,MYH14,CSRNP3,SELL,RPH3A,SLC1A7,LIMS2,SMARCD3,LIMCH1,MAPK8IP3,WSCD1,PCDHGA10,HEY1,TIMP4,HEY2,R3HDM1,SEZ6L,SPHK2,NT5M,KCNAB1,MVB12B" Drug 2635_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ASIC1,ADORA1,ADORA2A,LTBP4,PPFIA2,AQP4,MARK4,RASL11B,ATP1A3,SLC4A4,SLC2A11,N4BP2L1,ADAM23,SCAPER,MTMR3,CFAP410,CA4,ARHGEF1,ARHGAP33,SOCS6,SLIT2,NRXN1,FADS2,AKAP7,WHRN,LRIG1,PDE4DIP,SPOCK3,RABGAP1L,SIDT2,EFNB3,MTSS1L,NCALD,ZNF589,C1orf61,IQCG,TRAF3IP2,HAS2,IL6R,INPP5B,MSI1,NDUFA5,NOS1,NTRK2,ENPP2,CAMKV,RETREG1,PACSIN1,MAPK8,SAMD9,SLC6A15,RGS10,STUM,SLC2A5,SLC6A8,SOX2,SPTAN1,IQSEC2,NPAS3,CLSTN2,MAPK8IP3,ATP11A,CUX2,PCDHGA1,OBSL1" Drug 4612_UP Capsaicin [404-86-4]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ASPHD1,ACHE,SPARCL1,SEMA7A,CDC14B,BRINP2,CACNA1G,CFAP410,SEPT7,TAOK2,FAM149A,SH2B1,PDE4DIP,ARHGEF4,CTNND2,MFAP3L,C2CD2L,SV2B,DRP2,DTNA,EDN3,EDNRA,EFNA3,EIF5,AGAP2,NSG1,SIGLEC8,MYOZ2,GNAL,GRM1,ELOVL5,IGSF1,IL6ST,KCNJ4,KCNJ5,SMAD1,MATN3,AFDN,MMP16,NEFM,NF1,SLCO1C1,NOS1,SNTG1,ST8SIA5,FA2H,POU3F2,PPP5C,PRKAR1B,PRPH,RGS12,RYR1,RIMS1,IZUMO4,ZNF423,NFASC,CLSTN2,PHLDB1,MCF2L,TPM3,FLRT2,WIPF1,ZIC3,KCNAB1,AP3B2" Drug 2379_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "PLA2G6,CDC42BPA,ARRB2,PDE8B,ASPH,C5,CACNA2D1,USP2,SLC16A4,SLIT2,RCHY1,PDE4DIP,DZIP3,PPP1R16B,SPOCK2,TRAPPC9,DTNA,SEZ6L2,CELSR3,ELAVL2,MRNIP,DLC1,FGF12,CAMSAP1,IQCG,GPR153,GCNT2,ADAM28,RUNDC3A,FERMT2,IL1RAPL1,ATXN2L,MEF2C,TAGLN3,NEUROD1,NF1,SERPINE2,CCSER2,MINDY2,TMEM206,ABLIM3,PEX26,EPN2,LIMS2,FAM214B,SLC11A1,SLC20A2,SNCA,PALLD,TMCC1,ZCCHC24,SOX10,ZSWIM8,KDM4C,PLCB1,ASTN2,TAC3,TBCEL,WSCD1,TCF7L2,CRTC1,HEY2,RBFOX2,SSBP2,BEST1" Drug 3206_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "NDRG2,AK2,GAS7,AQP4,PRX,MARK4,PROM1,CFAP410,CA4,CALB1,CAMK2B,CBFA2T2,CNN3,WHRN,ARHGEF10,SIPA1L1,ARHGEF4,NOS1AP,DCT,MFAP3L,DUSP9,EFNA3,EGFR,TNK2,CEND1,NRN1,SORBS1,GPR153,ZNF44,DENND2A,ERAP1,MSL3,IRF8,MAP4,MAPT,GIT1,KCNK10,PCDH8,CDK14,SLC25A23,PMP2,PTPRO,KLHDC8A,TCP11L1,SEMA6D,ASAP3,PREX2,PKNOX2,SLC6A8,SLC22A4,OGDHL,SNAP25,MYT1L,KIF21B,PHF24,SLC19A3,GPR161,TK2,CABIN1,TRPM2,FAM155A,XRCC4,WNK1,DNALI1,PHTF2" Drug 3790_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "TTYH1,ACTN2,AMH,ARHGDIG,SLC2A11,ADAM23,INA,CDH8,CABP1,ABCG1,RIMS2,SPOCK2,SMG7,DMPK,TRAPPC9,EFNA3,MTSS1L,EFS,DCTN2,CAMKK2,CHL1,ERAP1,RAB30,LILRA2,GRIA4,GRM1,IRAK3,HRH3,HLF,HTR2A,ICA1,KCNF1,KCNH2,KCNN1,KIF5C,LSS,MBP,MOBP,CD200,MSI1,ADAM22,NEFM,NPR2,PCBP3,NTRK2,OMG,P2RX7,GPR85,PRKAR1B,CCDC40,SCN2A,ITSN1,SLC11A1,SLN,FNBP1,SSTR1,TAC3,OBSL1,THRA,TPM2,TRH,CA14,SPHK2,PRDM2,PARP6" Drug 6505_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ADORA2A,SYT13,CADM3,N4BP2L1,FGF17,RUNX1T1,CD86,FOXN3,CHGB,CHN2,PLEKHB1,CHRNA4,HOMER3,WHRN,CABP1,IFFO1,ENTPD4,RGS6,ARHGEF10,SNPH,HP1BP3,GSDME,DMPK,SHANK1,EDNRA,EFNA3,AASS,C3orf18,HSD17B14,ERCC2,NRN1,SORBS1,GLS,ADAMTS13,GRM3,RASSF8,HLF,HPSE2,SYNPO,ITIH2,JAK2,KCNC1,KCND3,PACRG,NDUFA5,NTRK3,MTRF1L,SPATA6,MAPK7,PROX1,RASGRF1,RGS12,SBF1,SLC1A7,SNCA,DDN,JMJD6,PLCB1,AP4E1,SLC44A1,ZKSCAN5,FLRT2,LAT2,WNK1,PLSCR4" Drug 4007_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ACTN2,ADD2,ANK1,APAF1,MADD,BCHE,CFLAR,FUBP1,BTRC,HAP1,CBS,SCARB1,CDC42,PLEKHB1,CLCN4,CNTFR,AKAP5,ENTPD4,CRY2,FEZ1,EDRF1,EDIL3,EPHA5,ETV1,KIAA1109,FGF14,PDLIM5,PRELID3A,GAB1,SPACA9,HSD17B1,TJAP1,IL12A,KIT,MDM4,NPR2,NTRK2,NLE1,PLCD1,SPATA6,POU3F4,CNNM2,PTPRN2,C1orf54,SUSD4,GAL3ST4,RGS4,GSTCD,STUM,TNIK,ZHX3,ZNF423,PHLDB1,VAMP1,COBL,EXOC7,ADGRL3,SLC44A1,R3HDM1,TNS1,SSBP2,UCHL1,ZNF24,WNK1,PARP6" Drug 5680_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ADORA3,AMPD3,FGF17,CALB2,RUNX1T1,SLC16A4,CDH10,FOXN3,CLCN4,DNAJB5,ARHGEF6,NCOR2,ARHGEF4,HDAC9,RIPOR2,BRINP1,DCC,ELMO1,TMCC2,EDNRA,EDNRB,EGFR,RASGRP2,FHL1,C1orf61,DCTN2,GABRA2,GAP43,GFER,PCLO,NR3C1,GSN,IRAK3,KLF12,HNMT,KCND3,KCNH1,KCNJ4,ADAM11,ADAM22,LYRM9,PDE4A,ENPP2,PRKCB,DCHS2,PTX3,RAB3IL1,GAL3ST4,KLHDC8A,ZNF821,SH3BP2,PKNOX2,CXXC4,MAPKBP1,ZC4H2,MLC1,JMJD6,SYT5,TCF4,SYNE1,PHF24,CRTC1,TEX15,PRMT8,ADAMTS9" Drug 3842_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "SEMA6A,ALK,BEGAIN,CDC42BPA,KCNAB2,APOC1,AQP4,SEMA4G,BRINP2,ATP2B2,ST3GAL5,SCAPER,MYRF,CACNA2D1,CAMK2A,INA,CDO1,SLC22A6,ARHGEF6,CPS1,CTIF,RUSC2,ATN1,EFNB3,EGFR,TNK2,SPEG,TUBB4A,AGAP2,TDRKH,GRM3,KLF12,KCNQ3,KIF5A,LMO1,MAP4,MEF2C,MID1,NNAT,PCBP3,NUMA1,OMG,GPR85,STRN3,VPS13C,FAM120C,RAB3A,MRAS,OGDHL,RBM34,ZNF423,AJAP1,SYT11,ARC,POPDC3,ATP11A,WSCD1,ZEB1,SZT2,TNS2,PCDHA6,TEX15,ZIC3,SPHK2,SLC30A3" Drug 3537_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "DPF1,TKTL1,ADGRF5,ALDH4A1,ADAM23,BTRC,CFAP410,CACNA1A,SLIT2,TPP1,FADS2,CSF1R,SIPA1L1,CNTNAP2,PHF14,SPOCK3,SLC12A6,EDNRA,PLXNC1,SORBS3,TENM1,TNK2,SPEG,ST3GAL6,KIAA1109,FOXG1,AGAP2,MALT1,RND1,GNAS,GNG4,LPAR4,ATXN2L,ELOVL5,IFI16,INPP5B,ITIH2,MEIS2,MGAT3,AFF1,NELL2,NEUROD1,PDE1C,PDE3B,PPP5C,PRPH,PTCH1,ZSCAN32,RAB3A,PNMA8A,RPS6KA2,SYBU,SMTN,LIMCH1,SNCA,ZNF415,MAPK8IP3,KIAA1107,TEX15,R3HDM1,LMF1,MKRN3,ITM2C,PHTF2,SENP7" Drug 3883_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-09 1.02E-04 2.24E-07 2.55E-06 65 199 "ADRA1D,SEMA6A,ALCAM,ANK1,AQP4,ASCL1,CHRD,ATM,KSR1,CACNA1I,CAMK2B,CAPN3,CDO1,CHI3L2,ZFYVE9,SNCAIP,FAM169A,CNIH3,MFAP3L,C3orf18,RASGRP2,CAMKK2,GAB1,HPGDS,GLYR1,GLS,POLL,PRUNE2,TDRKH,IL11RA,ITIH2,KCNJ5,L1CAM,MAPT,MATN3,MEF2C,KITLG,MYH7,NNAT,LRP12,NECAB2,MINDY2,PTAFR,PTHLH,PTPRH,ENOX1,ZDHHC14,RFX3,RGS12,KCNIP1,SH3GL3,SLC6A9,ZSWIM8,PEG10,TROVE2,MAPK8IP3,ROBO3,CRTC1,SLC35G2,THBS4,TPM2,TRPM2,ZNF711,MVB12B,JPH3" Drug 3227_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.11E-09 1.03E-04 2.25E-07 2.56E-06 61 182 "ADD3,NME5,CDC14B,BMP7,ST3GAL5,BTRC,CLGN,WHRN,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,TSPAN5,OPTN,EFNA3,EFNB3,TUBB4A,IQCG,DPYSL4,SORBS1,FYN,CYP46A1,RND1,RAB40B,STON1,KIF5C,MXI1,NEK1,SERPINE2,SERPINI1,PIK3CD,PMP22,GRAMD1C,PRPH,RAB3A,GAL3ST4,RPS6KA2,SH3BGR,SH3GL3,PPM1E,ASAP3,WDR47,ZCCHC24,KIF21B,BEX1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,LAT2,ZNF45,SLC30A3,GDPD5,NAV2,SLC17A7" Drug ctd:D009020 Morphine CTD 2.14E-09 1.05E-04 2.29E-07 2.60E-06 119 448 "DSCAML1,ADCY6,ADCY8,TMCC3,ADORA1,ADORA2A,AGT,BCAS1,AQP4,ARRB2,CALB1,CAMK2A,CBLN1,CCK,CCKBR,CD38,SEPT7,NRXN3,ABCG2,CNR1,CREM,RGS6,CMTM5,CYBB,AK5,DLG4,DPYSL2,DRD1,ST8SIA3,EGR3,RGS17,NRN1,TUBB4A,PPP1R1B,FGFR1,ADGRA1,GABRA1,GABRA4,GABRG2,GAD1,GAD2,ARPP21,GCNT2,GFAP,CSDC2,PCSK1N,GNAS,GRIA1,GRIA2,GRIA4,PLCD4,GRIK1,GRIN1,GRIN2C,NR3C1,GRM1,GRM5,FAM107A,HPCA,HP,OPALIN,IDH3B,SOWAHA,IGSF1,IL12A,MAP2,MAPT,SYT9,FXYD7,NCAM1,NEFH,NOS1,NPY,NRCAM,GPR88,OPRL1,PDYN,GNG2,PENK,ABCB1,PLCD1,PRKCB,PRKCG,MAPK3,RELN,RAB3A,RGS4,S100B,ASIC4,SELL,SGK1,DOCK10,NTNG1,RPH3A,SLC6A1,SLC6A7,EFHD1,SNCA,SST,SEPT8,PHLDB1,PLCB1,SYT5,TAC1,TACR1,PDLIM2,CUX2,SYNE1,CDH22,TLR4,BEX4,TRH,PRR18,CCDC136,ZIC1,SLC17A7,TMEM163,SLC17A6,GJC2" Drug 4200_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-09 1.09E-04 2.36E-07 2.68E-06 64 195 "APC,SHROOM2,CDC14B,RASL11B,NRP2,SCAPER,CFAP410,RUNX1T1,CHN2,DNAJB5,HOMER3,ERC2,CTH,DOCK4,SGSM2,DTNA,ECM2,EDIL3,HIPK3,COQ7,EPHB1,PTK2B,ZNF589,IQCG,FLT1,ANKFY1,PDLIM5,CSPG5,PNMA2,GAD2,ZMYND11,DISC1,ADAM28,GNAL,GPR17,GPER1,IGFBP1,IL6ST,LIG4,VWA5A,MARK1,KITLG,NCAM1,NF1,NTRK2,PCDH9,PDE2A,RETREG1,PLCD1,PTHLH,PTN,PTPRG,PTPRN2,SH3TC2,FAT4,RGS3,RGS4,KCNIP1,TNIK,KIAA1107,ARHGEF12,PRDM2,SLC17A7,HRASLS" Drug 3620_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-09 1.09E-04 2.36E-07 2.68E-06 64 195 "APOC1,CDK13,MARK4,PTCH2,FGF17,CAMK2B,BRSK2,USP2,COL9A3,SH2B1,RIMS2,ARHGAP24,CTIF,SMG7,TMCC2,TRAPPC9,DPP6,ECM2,DYRK1A,C3orf18,ERCC2,FGF1,GAP43,CPLX2,ALDH1L1,GRM1,IRAK3,INPP5B,KCNB1,KCNN1,LMO1,VWA5A,MAPT,MDFI,ZNF862,OGG1,SNTG1,PLCB2,PLCD1,C19orf57,POU3F4,CEP41,PTAFR,ACSM5,RAD52,PNMA8A,ASIC4,STUM,RASA3,ASAP3,SLC6A9,SLC9A5,SNAP25,TNIK,NMNAT2,PEG10,ZBTB43,ATP10B,SYT11,VAMP1,SYN2,TRIO,WIPF1,NT5M" Drug 7372_UP Ofloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-09 1.09E-04 2.36E-07 2.68E-06 64 195 "ARID1A,ADCY6,NME5,PPFIA1,MADD,CDK5R1,MTMR3,TAOK2,KIAA1549L,NCOR2,RUSC2,SMG7,RABGAP1L,KBTBD11,DLG4,EXOG,DTNA,DUSP9,MBNL2,IRAK4,MRNIP,PLEKHO1,COQ7,F5,TUBB4A,FER,FGF1,FGFR1,ANKFY1,GAB1,GLRB,MSL3,CNTRL,ARHGAP19,DHX35,TJAP1,IL12A,DIPK1A,ITPKA,KIF5C,NOVA2,CDK14,APTX,PTHLH,RAB3A,RAD52,RGS7,KCTD17,EMID1,TRAPPC13,ST6GAL1,SLC4A3,SPTAN1,IQSEC2,DDN,ST5,SEMA4A,SMG6,ARHGEF12,TMEM121,TLR4,NSD2,UBE3B,KAT6A" Drug 2566_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.23E-09 1.09E-04 2.36E-07 2.68E-06 64 195 "NDRG2,MTUS1,APBB2,ATP6V0A1,ST3GAL5,SGCE,HIP1R,INA,SLC16A4,CLGN,CRLF1,SOCS6,FEZ1,PDE4DIP,SLITRK5,DZIP3,EDRF1,DOCK4,RIMS3,DNAJC6,GSDME,DLG4,RCAN1,FAM13A,ABI2,TNK2,NCALD,RRAGB,CEND1,PTK2B,FHL1,B3GAT1,LYVE1,GPR19,RAPGEF4,GRM1,GSN,PADI2,KLF12,ITGAM,KIF5C,NCAM1,NRCAM,PLCD1,POU6F1,PPP5C,KCTD17,TTLL7,PPM1E,SLC1A3,PALLD,TNIK,CAND2,SPTB,RAP1GAP2,RGL1,PHLDB1,STXBP1,VAMP1,DNMBP,AHCYL2,TMOD1,TPM1,FLRT1" Drug 7377_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-09 1.09E-04 2.36E-07 2.68E-06 64 195 "ABR,ASIC1,ADCY6,AMPD3,SHROOM2,RGS20,MARK4,N4BP2L1,BTRC,CACNG1,PTBP2,KRIT1,CDC42,SOCS6,ZFYVE9,DNAJB5,QKI,CPS1,GIT2,DBT,ARMCX2,SMG7,CHRDL1,DPH1,DTNA,COQ7,ETV1,RRAGB,FGFR1,ANKFY1,ATP2C1,ZNF276,GLRB,CNTRL,SPACA9,SHISAL1,IL6ST,ITPKA,MBP,TAGLN3,RETREG1,PLCD1,ELOVL2,FAT4,ENOX1,CSRNP3,FUZ,DZIP1,TNIK,DOK5,SPTAN1,SS18,SYT1,ASTN2,IQCE,TCF7L2,AHCYL2,METTL3,ZKSCAN5,HIRA,XRCC4,SCG2,UBE3B,RNF146" Drug CID000003763 isoflurane Stitch 2.28E-09 1.12E-04 2.40E-07 2.74E-06 83 279 "ASIC1,AGT,AK2,ALAD,APLP1,APOC2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,CACNA2D1,ASIC3,CHRM1,CHRNA4,CHRNB2,BOC,SNPH,DMD,TRAPPC9,CASP8AP2,ABCC9,EDN1,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MSTN,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HBA1,TNFAIP8L3,KCNA1,KCNK2,KCNK3,KCNMA1,MAG,NBL1,NODAL,NOS1,NPY,KCNK10,PIK3C2A,PRKCG,MAPK3,RYR1,RYR3,MAPK12,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,ARX,SCN3B,DDN,VAMP1,LEFTY2,HEY1,TPM3,NSD2" Drug 2955_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.38E-09 1.17E-04 2.50E-07 2.84E-06 63 191 "ABHD6,ACTN1,ADORA3,MRTFA,TRMT9B,AMPH,BIN1,CDC42BPA,BCAS1,RASL11B,CACNA1G,CAPN3,NMT2,HOMER3,PICK1,ABCG1,DZIP3,SMG7,DLG3,ECM2,CNNM1,EFNA3,CELSR3,C3orf18,FGR,CAMSAP1,AGAP2,EFCAB2,GPR153,ALDH1L1,PCDH17,PCSK1N,PADI2,HNMT,KHK,TAGLN3,MYT1,NNAT,PCBP3,PFKFB2,ST8SIA5,PLCL1,PILRA,PPARA,PPP2R2B,SEC61A2,ZFHX4,SYNDIG1,KCNIP1,NTNG1,EPN2,SMTN,SLC11A1,SPTB,NPAS3,ATP11A,PDLIM2,TMOD1,UBTF,FLRT2,VIPR2,SLC13A3,ZBTB16" Drug ctd:D011188 Potassium CTD 2.52E-09 1.23E-04 2.64E-07 3.00E-06 42 106 "ADORA1,ADRB2,AGT,APP,NGB,CNR1,SLC12A6,ABCC9,EDN1,SGK2,GPD1,GRM1,IGF1,KCNC1,KCND2,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ10,KCNJ11,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,NPY,KCNK10,PDYN,PENK,MAPK3,MAPK8,SGK1,SHANK2,SLC12A4,SST,ABCC8,TAC1,SIRT1,SGK3,NLRP3" Drug 3698_DN Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "C1QTNF3,MRTFA,AMPD3,APAF1,KIF1A,SCAPER,BAIAP3,CAMK2B,CBS,SEPT7,LARGE1,B4GALT6,TAOK2,PLAA,CNTFR,AKAP7,HAPLN1,CNTNAP2,SLITRK5,ARMCX2,DMPK,DSCAM,DTNA,EFNA3,PLXNC1,CORO2B,ATP8A1,FGFR1,PCDH17,SPACA9,KLF12,HSD17B1,KHK,MAN2A2,GIT1,NF1,SPATA6,PRKAR1B,PRPH,CNNM2,PLPPR1,PTPRB,FAM120C,RAB3A,GAL3ST4,RGS10,CSRNP3,SCN8A,ZNF821,MRAS,ASAP3,DZIP1,PREX2,PKNOX2,ARHGEF40,SNCA,ARHGAP26,COLGALT2,ATP11A,MCF2L,CADM1,VAV2,LMF1,LAT2,WNT7A" Drug 5621_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "ACTN2,ALCAM,AMH,SEMA7A,PRX,RGS20,CHRNA4,LHX2,EPS15L1,PICK1,IFFO1,DCT,SMG7,EDNRB,SIDT2,PLXNC1,LPAR6,EPB41,ETV1,FGF13,FHL1,FYB1,GAD1,SIGLEC8,RND1,WIF1,PTGDR2,KCNN1,KIT,VWA5A,MAOB,MYL3,ZNF862,NEFM,NEK1,CNOT4,OPCML,PENK,FAT4,KCNIP1,ASAP3,CPEB3,ST6GAL1,SLA,SLC2A5,CCDC88A,KIF13A,SYT11,VAMP1,SYN2,WSCD1,ZEB1,HIF3A,TMOD1,TRO,UBE3A,AMOT,UCHL1,XRCC4,SF1,SLC30A3,EVI5,GJC2,AP3B2,JPH3" Drug 2278_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "ALCAM,AMPH,SEMA7A,APAF1,LGR5,MARK4,SLC2A11,ATP6V0A1,GYG2,BAIAP3,CFAP410,CBFA2T2,ZFYVE9,WHRN,TCEAL2,CREM,CTIF,DCT,MFAP3L,TMCC2,DRD1,EDIL3,HSD17B14,MTSS1L,DLC1,DCTN2,TBR1,SIGLEC8,LYVE1,GPM6A,GPM6B,GPR22,GPER1,GRK4,GRM8,PTGDR2,HLF,KCNK2,KIF5A,NPPA,PDE4B,PURG,PACSIN1,CEP41,SAMD9,PTHLH,RAD52,C1orf54,RPS6KA2,SYNDIG1,ASIC4,ASAP3,FAM214B,PKNOX2,SLC11A1,SLCO1A2,FAIM2,HECW1,SSTR2,SYP,SLC35G2,TGFBR3,FAM155A,UCHL1,FAM13C" Drug 3735_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "TTYH1,ASPHD1,ADRA1D,ANK3,APAF1,DNAH17,N4BP2L1,ATP6V0A1,NRP2,BMP7,FUBP1,CFAP410,CDO1,RAB28,CLCN4,IQCK,ABCG1,LRIG1,PDE4DIP,EXOG,TRAPPC9,DSCAM,RCAN1,ABCC9,LPAR6,EPHA5,KIAA1109,OLFM1,BAIAP2,FYB1,ALDH1L1,SRCAP,ADAM28,RUNDC3A,GNG3,GPD2,GPR19,MAP4K5,KCNJ5,LAMA2,MMP16,NDP,NFYA,OPCML,PDE4B,PDE4D,MAPK8,RGS4,MYH14,PNMA8A,SUPT20H,FNDC3A,CNKSR2,ARHGEF40,SCN3B,HECW1,PLCB1,ASTN2,ADGRL3,TNS1,UCHL1,PDIA2,LAT2,ZNF24,KCNAB1" Drug 1504_UP Khellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "NDRG2,ADORA1,C1QTNF1,SRPX,LTBP4,AMT,CDC42BPA,PRX,ALDH4A1,FGF17,CFLAR,SCAPER,MTMR2,CACNA1I,HAP1,CAMK2B,CLGN,TAOK2,CLU,NIPBL,RCHY1,NECTIN3,LYPD1,SMG7,DTNA,EDNRA,FEM1B,PLXNC1,EIF5,VPS13B,LRRC23,STX2,ZNF589,FHL1,PDLIM5,GNG3,NR3C1,GUCY1A1,KCNH2,MBD1,SETD4,CDK18,PLCD1,PRKAR1B,MAPK8,ZSCAN32,ZDHHC14,SH3BP2,FRMPD1,PEX26,RAB3GAP1,IQSEC2,SAMSN1,SYN2,CRTC1,THRA,TK2,TMOD1,BEX4,TPD52,CDK20,WIPF1,XRCC4,PRDM2,SLC17A7" Drug 6150_UP Ramipril [87333-19-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "ADORA1,OGT,APBB2,APOC1,ASCL1,ALDH4A1,BMP7,BAIAP3,MAP7,RUNX1T1,CBARP,ASIC3,SLC22A6,CLCN4,SLC24A2,SIPA1L1,SPOCK2,SV2B,SPOCK3,ATN1,DSCAM,CELSR3,ING4,AGAP2,ALDH1L1,GNAL,GPR19,GRIN1,CELF3,SCIN,KCNB1,KCNN1,KIF5C,MBP,MPP2,MYBPC1,NRCAM,NTRK2,PDE4A,FSD1,PPP2R2B,PROX1,LRRC49,PNMA8A,FERMT1,NTNG1,ST6GAL1,SLC1A2,PKNOX2,SLC11A1,SLCO1A2,FAIM2,IZUMO4,CAND2,HECW1,DDN,VAMP1,ADGRL3,WWC1,DMXL2,TEK,DNAH7,KCNE5,UGT8,SH3GLB2" Drug 2558_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.63E-09 1.29E-04 2.71E-07 3.09E-06 65 200 "ACTN2,AMH,CDC42BPA,PKP4,ARHGAP5,ASCL1,ASPH,BACH1,FUBP1,CFAP410,MAP7,INA,CHM,CHN1,CHRNB2,ZFYVE9,CSF1,CSNK1E,VCAN,RUBCN,DGKG,DAPK3,CNIH3,MFAP3L,TMCC2,DTNA,LPAR6,KCNMB2,BAIAP2,AGAP2,CAMKK2,ATP8A2,GPD2,PTGDR2,IGFBP1,TJAP1,LAMA2,MAP4,NEFM,NINJ2,CLDN11,P2RY1,PDE3B,PPARA,PRKCZ,RGS3,ZFHX4,TCP11L1,ZNF821,RASA3,SCG5,PREX2,SLC6A9,SNCA,CAND2,SPART,ATP10B,ARHGEF9,PLCB1,SYT5,AHCYL2,HIRA,FLRT1,XRCC4,NAV2" Drug 7550_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.68E-09 1.31E-04 2.76E-07 3.14E-06 61 183 "ABHD6,ADD3,KIDINS220,ALAD,ARNTL,BMP7,ST3GAL5,BAIAP3,SPAG9,USP2,SYNGR3,NMT2,WHRN,PDE4DIP,KIAA0513,GIT2,DNAJC6,OPTN,EFNA3,EFNB3,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,GPR37,RNFT2,DIPK1A,KIF5C,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,SLC25A23,PKIA,PRPH,PTCH1,QDPR,SH3GL3,PPM1E,SYBU,WDR47,ZCCHC24,SPTAN1,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,DNAJC12,PLPPR2,SLC17A7" Drug ctd:D020849 Raloxifene Hydrochloride CTD 2.70E-09 1.32E-04 2.78E-07 3.16E-06 200 860 "SERPINA3,RBM10,ADCY2,KLRC4,ADORA2A,AGT,ALAD,ALCAM,ANK3,BCAS1,BRINP2,CHRD,NCOA1,DDX3Y,DYNLL1,ATP1A1,STX16,ADGRB2,BMP7,CDK5R1,SYNJ2,CACNA1I,LDLRAD4,MMD2,CA4,CA12,CALB2,CALM1,CD86,ENTPD2,CDH2,CDO1,COPB2,ADGRG1,CLCN4,CLU,CLTB,QKI,NRG2,FAM171B,C2CD2,HAPLN1,NCOR2,ABCG1,AATK,CSF1,LRIG1,MICAL2,OSBPL3,GREB1,RIPOR2,MATR3,PITPNC1,SPOCK3,ARNT2,CDON,TOM1,FIS1,EDN3,EDNRA,PHC2,RASGRP1,EGFR,MBNL2,EGR3,EIF5,EIF1,ENO2,RCAN2,ERBB2,ERBB4,F3,F8,TUBA1B,TAOK3,EFEMP1,OLFM1,AMOTL2,FHL1,CAP2,FLNC,TACC2,FUT9,GABRG1,TRAF3IP2,GAD1,AHCYL1,GDF9,GFRA2,CSDC2,GHR,GLRB,GLUL,CBX1,ADGRA3,GPER1,GRB10,NR3C1,GYG1,HAS2,HBA1,ELOVL5,HMGB1,SYNPO,HTR2A,HTR5A,IGF1,IL12A,JAK2,KLRC2,KLRC3,STMN1,MAN2A2,MID1,MN1,CD200,ADAM22,NBL1,NCF2,NF1,NPR2,PDE3B,PDE4D,PDGFRA,ENPP2,PDYN,PFKFB3,ABCB1,SERPINE2,SSH1,RETREG1,PMP22,PMS2,PRKCZ,MAPK3,PTPN13,PTPRE,PTPRH,PTX3,PEX5,RASGRF1,RBBP8,RET,RGS4,RGS10,ROM1,RPS6KA2,RYR1,SAFB,SALL1,SFPQ,SGK1,SYBU,CLSTN1,ABLIM3,SLC1A2,SLC1A3,CDK5RAP3,ATF7IP,SLIT1,SLN,RCOR3,LIMCH1,SNCA,PALLD,SON,MYT1L,TNIK,ZCCHC24,SPP1,SRPK2,RGL1,STX1A,ANKRD28,TACC1,KAZN,TAF9,DNMBP,WWC1,ZEB1,PCDHGA3,DOCK9,DICER1,HEY2,TMOD1,TMPO,CABIN1,TPM1,SSBP2,SGK3,FLRT1,XPO1,NDRG4,SEMA3B,NAV2,SLC17A7,CERS6,ADAMTSL3,NLRP3,SPATA13" Drug ctd:C008261 lead acetate CTD 2.73E-09 1.34E-04 2.80E-07 3.19E-06 384 1862 "RALGAPA1,DGCR6,KCNH8,SYN3,ACHE,TKTL1,ADCY8,ADORA1,ADRA1D,KIDINS220,AP2A1,OSBPL6,WDR35,DISP3,ALAD,SEMA6A,ALCAM,ANK2,APAF1,APOC2,APP,LGR5,MADD,ARHGDIA,CDK13,ASPH,DDX3Y,CHID1,ALDH7A1,B3GALT2,KIF1A,BCHE,BID,PROM1,CDK5R1,LDLRAD4,CA8,KALRN,CAMK2A,CAMK2D,CAPN3,CARS,SLC5A11,FMNL3,AIFM1,CD86,SCARB1,CDH2,CLGN,CLCN3,CLTC,ABCG2,MAP4K4,AKAP7,COL4A5,COL9A1,COL9A3,COL11A2,SLC4A7,CP,CREB5,SLC32A1,NCOR2,CSF1R,CSF2RA,LRIG1,PDE4DIP,CNTNAP2,UBXN2A,GREB1,USP6NL,CX3CR1,SEC14L5,CYBB,HDAC9,GPRASP1,ARHGAP24,ZFYVE16,EARS2,DAPK1,DBN1,HEPH,HP1BP3,KIF19,DLG4,GRIN3A,OLIG1,CDON,DNM2,DPYSL2,DRD1,ARRDC4,DNAJB6,EDNRB,HEYL,FRY,CELSR3,EGFR,LPAR6,EIF4G2,ELAVL3,ELAVL4,USPL1,LRRC23,EPHA5,EPHB1,ENPP6,ERCC2,IGSF6,CEND1,F5,TBC1D16,ZIC4,ZMYND10,FCGR3A,FCGRT,FGF1,FGFR1,SEC23B,C1orf61,PCYOX1,EVL,EFCAB2,JKAMP,ARFGAP2,ATP6V1H,NSG1,MPP6,FYN,NEURL4,GAA,GABRA1,GAD2,B4GALNT1,NKX6-2,ARPP21,GALR1,ERAP1,MTHFD2,DISC1,GATM,GBX2,GFAP,PPARGC1A,KIRREL3,LYVE1,GK,DBF4,TNRC6A,GLUL,CBX1,LOXL3,GNAO1,LNX1,GPD1,ATF7,EML4,GRB10,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GRM8,GSTT2,GUCY1A1,GUCY1B1,MAP4K5,FRMD3,ACOT7,HMX1,HNF4G,IGFBPL1,TLX1,CFAP126,HSP90AA1,HTR5A,IGF1,IGFBP1,LRRCC1,PLD5,IL6R,IL12A,INPP1,KCNJ4,KCNJ5,KCNJ16,KHK,KIF5A,LAMA2,CAMK2N2,LIG4,SMAD1,SMAD9,MAG,GPR155,MAP2,MAPT,MAT2A,MATK,MBP,LDLRAD3,MEST,MIA2,KITLG,MID1,MITF,CCDC80,BLOC1S2,MT1M,MT3,CTNNA3,MYCN,MYH6,MYL3,MYO6,NCAM1,NCAM2,RCOR2,NEFM,NEFH,NEUROD1,NFIA,NFE2L2,ALDH1L2,NFIX,NFYA,NKX2-2,NOS1,SLC11A2,NTRK2,DDR2,P2RX7,P2RY1,ZNF827,PAX6,PDGFRA,ENPP2,PDPK1,PDYN,BEST3,ZNF655,SNX10,RETREG1,PLP1,PCDH18,ZNF426,ASPDH,SCHIP1,SPATA6,FA2H,PPARA,PPP5C,PRKCB,PRKCG,MAPK3,MAPK4,MAPK8,MAPK9,MAPK10,PRPSAP2,MASP1,RELN,KLK6,LAMA1,SIDT1,MTMR10,PTHLH,SPDL1,PTPRN,PTPRO,PEX2,ACSM5,PYGM,TMEM255A,RET,ERI2,RNASE1,RNASEL,ROBO1,ROBO2,RPE65,UEVLD,GLDN,MAP6D1,KCNIP2,STX1B,RXRG,RYR3,S100B,ATXN1,SCN7A,HES6,SFPQ,SGK1,FERMT1,SHMT2,FNDC3A,SLC1A2,SLC1A3,SLC2A5,SMTN,LIMS2,SLC6A8,SLC6A9,SLC6A11,TRIM67,SLC12A2,BTBD7,SLCO1A2,RIMS1,SNAP25,SNCA,SOX3,TNIK,SP2,LHFPL4,HECW1,MYCBP2,SPP1,KIF1B,NFASC,PBLD,THSD1,EPB41L3,STX1A,KANK1,JMJD6,VAMP1,SYN1,ARC,SYP,SYT1,TPCN2,PCDHGB6,WDR7,SYNE1,PCDHB9,SLC19A3,FRYL,HIF3A,TEX15,TF,ITGB3BP,TGFBR3,TJP1,HEY2,BEX4,ANKRD24,TNFRSF1B,TNNT1,TNS1,RUNDC3B,TRPC1,CA14,TSC1,UBC,UGT8,VGF,VLDLR,LAT2,WNT7A,SLC13A3,PLPP4,EVI5,LMAN2L,CIAPIN1,NAV3,SLC17A7,KCNAB1,PLD4,SLC17A6,RTN4,KAT6A,GJC2,SLC39A12,SSPN" Drug CID000003779 isoproterenol Stitch 2.73E-09 1.34E-04 2.80E-07 3.19E-06 163 669 "ASIC1,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,ALAD,BBOX1,AMPD2,AMPD3,ANK2,MYH7B,AQP4,ARRB1,PDE8B,ATP2A2,ALDH7A1,HCN2,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,CALM1,CAMK2B,CCK,P2RX6,CBFA2T2,CD38,LRBA,CHGA,ASIC3,CHRM1,CHRNA4,CLCN3,CLCN4,MYL6B,AKAP6,MYRIP,CREM,VCAN,DLG4,DMD,DRD1,ABCC9,EDN1,EDN3,EDNRA,LPAR6,TUBD1,KCNMB2,PTK2B,TUBB3,TUBB4A,PPP1R1B,ACTL6B,NRG3,TUBA8,GFAP,CRCP,GNAL,GNAO1,GNAS,LPAR4,GRK4,TUBA1C,GUCY1A2,GUCY1B1,HRH3,TNFAIP8L3,HPSE2,TUBB2B,ITGAM,KCND3,KCNH2,KCNK1,KCNMA1,AFDN,MXI1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,P2RY13,NEUROD1,NOS1,NPY,NPPA,NPR2,P2RX7,P2RY1,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PENK,PIK3C2A,PIK3R1,PLIN1,PPARA,PPP1R1A,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK7,MAPK8,KLK6,PYGM,QDPR,RIC8B,RNH1,MYH14,GLDN,RYR1,RYR3,S100B,MAPK12,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,MYO18A,SLC6A7,SCN3B,SPP1,SST,ABCC8,TAC1,AZIN2,HIF3A,TF,ACTR6,TNNT1,TTPA,TUBB2A,TUBB1,VIPR2,P2RY12,TUBA1A,PCDH15,PLD4" Drug 5947_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "TKTL1,ADCY6,NME5,LTBP4,SYT13,DOC2A,TRMT9B,BIN1,CDC42BPA,ANK1,SEMA4G,PLA2G4C,MARK4,BAIAP3,CACNA1D,CDC42,CDH2,CHRNA4,TAOK2,WHRN,COL9A3,NRG2,SOCS5,RIMS2,EDRF1,DGKB,CTIF,ST8SIA3,EGFR,ING4,SORBS1,GAD1,DISC1,SRCAP,GNG4,SPACA9,CACFD1,PTGDR2,HNMT,ITIH2,KCNJ5,SMAD1,MMP17,NCAM1,RNASEL,NEK11,RASA3,SH3BGR,SLC1A2,SPTAN1,SPTB,MAPK8IP3,STX1A,JMJD6,KAZN,TCF4,TMEM121,TPM3,TRIO,FAM155A,VGF,NT5M,MVB12B,AP3B2" Drug 4963_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "SYN3,ASIC1,NDRG2,FAM131A,GYG2,MYRF,BAIAP3,CD86,CBFA2T2,CDH2,SLC22A6,HOMER3,CPS1,SH2B1,CSF1,RIMS3,DBT,SPOCK3,SIDT2,EIF4G2,SPEG,PIPOX,FABP7,FGFR1,AGAP2,GAB1,GAP43,SIGLEC8,ALDH1L1,GNG4,IRF8,INPP5B,ITIH2,KCNB1,KCND3,KCNN1,KCNQ3,MAP2,MGAT3,MMP16,NOS1,NTRK2,P2RY1,PDE4A,PLXNB1,PACSIN1,PRKAR1B,RFX2,RGS10,KCNIP1,SEMA6D,SCN8A,CNKSR2,SLC2A5,SHANK2,SLCO1A2,SLN,HECW1,TBCEL,WSCD1,ZEB1,AMACR,VIPR2,TIGD6" Drug 4357_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "KLRC4,NLGN4X,AGT,TRMT9B,BIN1,ANK1,APC,APOC1,LGR5,ADGRB1,CALB1,KALRN,INA,ARHGEF2,CBARP,AKAP5,NOS1AP,HDAC9,DAPK1,SPOCK2,CDON,ATN1,SGK2,ELN,SPEG,GAD2,NEU3,TOX3,GPM6A,GPER1,MAOB,MSR1,NTRK3,PALM,PCDH9,PCSK5,PFKFB2,MTRF1L,CDIP1,MINDY2,MAPK8,SAMD9,PTAFR,MARCH1,PID1,RFX2,RGS4,KLHDC8A,SLC2A5,BTBD7,KIF13A,TNIK,ZSWIM8,ZC4H2,MAPK8IP3,TBCEL,WSCD1,DICER1,AMACR,UCHL1,SCG2,KCNAB1,FAM13C,JPH3" Drug 4643_DN Iohexol [66108-95-0]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "MTUS1,AMH,CDC42BPA,APC,DDO,PDE8B,ATP2B2,CADM3,ADAM23,BAIAP3,CDH10,GPR37L1,CABP1,COL9A3,TCEAL2,DTNB,EDN1,HEYL,MRNIP,MTSS1L,ANKMY1,F5,ST3GAL6,GAD1,SIGLEC8,SEPT9,GFER,LYVE1,POLL,GPM6B,GPR17,GRIN1,ICA1,MOBP,ADAM22,NEUROD1,NOVA1,NUMA1,POLG,MAPK7,PTPRB,PEX5,ZSCAN2,RAD52,RGR,RGS12,ZNF821,SUPT20H,SLA,LIMS2,MYH15,SNCA,TSNAXIP1,DDN,FBXW11,THRA,TIAM1,AMACR,TRO,VIPR2,SPHK2,NT5M,EVI5,FAM13C" Drug 5606_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "DPF1,ADORA2A,AMH,ADAM23,KSR1,CACNA1G,INA,CD86,ADGRG1,NRXN3,WHRN,NCOR2,CNTNAP2,RUSC2,OLIG2,SPEG,FGF13,FGFR3,FHL1,GCNT2,LYVE1,POLL,GNAO1,SPACA9,GRM1,KLF12,ITGA7,KCNC1,KCNK2,KHK,KIF5A,MEF2C,MN1,ADAM22,NPPA,NTRK3,NUMA1,PFKFB2,NECAB2,RELN,PTAFR,PTH1R,NKAIN1,BEND5,SUGCT,TMEM206,KCNIP1,FRMPD1,ASAP3,SLCO1A2,KIF13A,PHLDB1,POPDC3,SEMA4A,ADGRL3,TEX15,HEY1,TRPM2,UCHL1,LAT2,XRCC4,SLC30A3,ITM2C,GJC2" Drug 4597_UP Naringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "NR0B1,PLA2G6,TRMT9B,ASCL1,CADM3,ADAM23,MYRF,LDLRAD4,CACNG1,USP2,ARHGEF2,TAOK2,EPS15L1,LY86,CREM,CRY2,PDE4DIP,ARHGEF4,RIMS2,EDRF1,BRINP1,RABGAP1L,ARNT2,EDNRB,ETV1,F5,C1orf61,SEMA4D,EFCAB2,GABRA2,ZNF44,HBS1L,ADAM28,RUNDC3A,TPPP,GUCY1B1,HSD17B1,ITGA7,KCNB1,KCNF1,KIFC3,LIG4,NNAT,PALM,PDE4D,SERPINE2,ZSCAN32,RASGRF1,RGR,RGS10,ZNF821,SH3BGR,NTNG1,WDR37,SLC2A5,SOX15,HECW1,IQSEC2,TK2,TLR4,CADM1,VAV2,ZNF74,GAN" Drug 4347_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "LTBP4,KCNAB2,GAS7,MARK4,PTCH2,KSR1,MYRF,CDK5R2,CFAP410,CACNA2D1,RUNX1T1,CCKBR,SEPT7,KIAA1549L,TPP1,SULT4A1,WHRN,ARHGEF4,RIPOR2,SPOCK2,CTIF,ST8SIA3,ELN,RASGRP2,FHL1,DLL3,FYB1,GLS,PRUNE2,HPSE2,IRF8,ITGA7,KCNB1,KCNH2,KCNJ5,KCNMA1,KCNN1,CD200,ADAM22,TAGLN3,NOVA2,PALM,PAX6,GPR85,PLCD1,PLTP,MTRF1L,CDIP1,POU3F4,MAPK8,PTPRO,KCNIP1,ZNF821,SLC2A5,KDM4B,SOX2,KIF21B,ZNF423,ZC3H13,SYT11,TACR1,SYNE1,HEY1,LAT2" Drug 4424_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "ASIC1,ADCY6,C1QTNF1,SEMA6A,CDC14B,SEMA4G,ARHGDIG,RASL11B,CACNA1I,BAIAP3,CFAP410,CALB2,RUNX1T1,SLC16A4,CHRNA4,CHRNB2,CRMP1,NCOR2,CNTNAP2,PIPOX,TUBB4A,ST3GAL6,SCARA3,FYN,ATP8A2,GRM7,GSN,HTR2A,JAK2,KIFC3,AFDN,ADAM22,MX1,MYO7A,NPPA,SNTG1,PCDH8,PDE1C,ENPP2,C19orf57,CEP41,MAPK8,GDPD2,PTPRN,FEZF2,KCTD17,TMEM206,RPS6KA2,SH3GL3,BCAN,SLC4A3,LIMS2,OGDHL,ZCCHC24,PEG10,TROVE2,ATP11A,KIAA1107,SYNE1,HEY2,UBE3A,XRCC4,SLC30A3,MVB12B" Drug 3517_UP Torsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "ARID1A,ADGRF5,ALK,SEMA7A,APBA2,APBB2,CFLAR,HIP1R,CACNA2D2,KIAA1549L,AKAP6,HINFP,MICAL2,NOS1AP,DAPK1,ARMCX2,SHANK1,DTNA,RCAN2,ZNF589,FGFR1,GABRA5,SIGLEC8,DISC1,GATM,GPM6B,RAPGEF1,GRM7,GSTM5,ICA1,KCNJ5,KCNQ3,MOBP,MSI1,ADAM22,MYO7A,NELL2,PDE3B,PLCD1,SPATA6,PACSIN1,PPP2R2B,PPP5C,PRPH,WDR25,CNTLN,RAB3IL1,FAT4,RGS12,ZFHX4,ST6GAL1,SMARCD3,ZCCHC24,TSNAXIP1,KDM4C,PEG10,ZNF423,VAMP1,WSCD1,TEK,GPR161,UGT8,WIPF1,NUP214" Drug 5673_UP Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "NDRG2,ADRA1D,PLA2G6,C1QTNF3,ABCD2,ALK,FGD2,CACNA1G,CAMK2A,RAB33A,STOML1,QKI,TCEAL2,CREB5,PLCH2,BRINP1,DBT,SRGAP3,DUSP9,EFNB3,ERCC2,NCALD,ZNF589,CAMSAP1,ATP8A2,MSTN,GFAP,LYVE1,GLI2,GNAL,PRUNE2,ATF7,GRIK5,GSN,ATXN2L,IGFBP1,ITIH2,KCND2,MAOB,MGAT3,MN1,MSR1,NCF2,NEUROD1,PCBP3,PLCD1,MTRF1L,PILRA,TRIM68,MYH14,SH3BP2,SNCA,DOP1A,UNC5B,SYT11,KIAA1107,SLC19A3,ARHGEF12,TEX15,ZFPM2,BEST1,ZIC3,MKRN3,NT5M" Drug 4590_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "ACTN1,ARID1A,ADRA1D,ADRB2,ADGRB2,ARHGEF1,ARHGAP33,FOXN3,RAB28,CSF1,CSF1R,HDAC9,TOX,KIAA0513,SIRPA,EXOG,DMPK,CDON,FEM1B,MRNIP,RGS17,SPEG,C1orf61,CINP,FYB1,SYT17,GBX2,TJAP1,INPP5B,KIF5C,LIG4,GIT1,SLC11A2,PDE1C,PFKFB2,GRAMD1C,PROX1,PTX3,BEND5,MYH14,ZNF671,TCP11L1,ATXN1,ZNF821,SCG5,BCAN,SLC14A1,THSD1,MAPK8IP3,VAMP1,MCF2L,TRIM2,SYNE1,OBSL1,CABIN1,TRIO,RUNDC3B,AMACR,VIPR2,LMF1,LAT2,WNT7A,NT5M,HPS4" Drug 4256_DN Tocainide hydrochloride; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "ASPHD1,AMPD3,PPFIA4,KSR1,BAIAP3,CDH10,CRLF1,TPP1,HOMER3,AKAP7,RCHY1,CSF1,ARHGEF10,VCAN,CNTNAP2,EDRF1,ARHGAP24,SPOCK3,DYRK1A,MTSS1L,AFF2,OGA,FYB1,SIGLEC8,ALDH1L1,RUNDC3A,GNG3,LPAR4,GRIK2,GRM1,GRM8,SOX21,HNMT,ITPKA,KCND3,KCNJ5,KCNN1,LMO2,MAPT,AFDN,ADAM22,NDP,PALM,PBX1,PMP2,SPATA6,FA2H,PTPRB,RALGDS,RGS7,IL17RB,ASAP3,KIF13A,VAMP1,TLR4,R3HDM1,ZMYND8,VAV2,SPHK2,REEP1,PARP6,KCNAB1,PARP11,FAM13C" Drug 5574_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.81E-09 1.38E-04 2.80E-07 3.19E-06 64 196 "DPF1,AMT,AQP4,AZGP1,CACNA1I,CBFA2T2,PICK1,WHRN,CRMP1,CSF1R,RIMS2,RASSF2,DAPK1,DMD,SHANK1,DRD1,AASS,SPEG,KIAA1109,DLL3,NEU3,NR3C1,GRM8,GSN,HRH3,SYNPO,KCNJ5,KCNN2,KIFC3,L1CAM,MAPT,AFDN,TAGLN3,NELL2,NNAT,NTRK3,PDE1C,CDK14,PIK3CD,PLCD1,LRP12,MAPK10,DCHS2,PTAFR,ZMAT4,RFX2,KCTD17,FRMPD1,ASAP3,CNKSR2,DZIP1,SLC2A5,SLC8A1,CXXC4,SPTB,ROBO3,KIAA1107,DNAH7,ICAM5,PIK3R5,CHST5,LAT2,XRCC4,MVB12B" Drug 6951_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.83E-09 1.39E-04 2.81E-07 3.20E-06 60 179 "MARK4,BMP7,ST3GAL5,BAIAP3,SPAG9,USP2,DNAJB5,AKAP12,CRYM,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNB3,RASGRP2,STX2,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,TDRKH,STON1,KIF5C,MITF,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,PIK3CD,RETREG1,PRPH,RAB3A,SEC14L1,SH3BGR,SH3GL3,WDR47,SLC6A8,ZCCHC24,KIF21B,SPTAN1,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,SMG6,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7" Drug 5336_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.83E-09 1.39E-04 2.81E-07 3.20E-06 60 179 "ABHD6,ADD3,NME5,ALAD,ALCAM,APLP1,BMP7,ST3GAL5,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TMCC2,TSPAN5,EFNA3,EFNB3,MBNL2,TUBB4A,FHL1,DPYSL4,FYN,CYP46A1,GLS,STON1,KIF5C,MITF,MXI1,NAP1L3,NEK1,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,PTCH1,RAB3A,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,DNAJC12,EVI5,GDPD5,NAV2,SLC17A7,ITM2C" Drug 3746_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.98E-09 1.46E-04 2.95E-07 3.36E-06 59 175 "ABAT,ABHD6,ADRB2,MTUS1,EPB41L5,ARNTL,ST3GAL5,HAP1,USP2,CBFA2T2,ABCG1,PDE4DIP,CNTNAP2,CTH,RIMS3,DNAJC6,PLPPR4,EDN1,EFNA3,MBNL2,RGS17,TUBB4A,TAOK3,BAIAP2,PNMA2,FYN,RND1,STON1,ITGA7,KCNH2,KIF5C,LIFR,VWA5A,MAPT,MMP16,PCDH9,PDE2A,PDGFRA,ENPP2,SERPINI1,PIK3CD,RETREG1,SYTL2,ENOX1,RGS4,SH3GL3,TNIK,NFASC,ELOVL4,CEP68,RGL1,SYT11,SYT1,SSBP2,DNAJC12,TRIM9,SLC17A7,PLSCR4,PHTF2" Drug 2738_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.00E-09 1.47E-04 2.95E-07 3.36E-06 63 192 "ANK3,ASPH,KSR1,CACNB4,DLGAP1,CHN2,PICK1,COL9A3,NCOR2,RIMS2,SPOCK3,SRGAP3,CDON,ABCC9,ST8SIA3,MBNL2,CORO2B,ZNF44,SIGLEC8,SEPT9,GNAS,GRK4,HNMT,HTR5A,KCND3,MAPT,MGAT3,AFDN,ADAM22,MYO6,NEUROD1,OPCML,PDE1C,PPP1R1A,PTPRB,RASGRF1,KHDRBS2,RGS4,SUGCT,NEK11,SCN2B,FRMPD1,FERMT1,NLGN1,SNAP25,ZNF415,SOX2,SSTR2,PLCB1,SYT5,TRIM2,PCDHGB6,THRA,TIAM1,SEZ6L,TRIO,TRO,OSBP2,LMF1,KLC2,KCNK12,SCG2,JPH3" Drug 2183_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.00E-09 1.47E-04 2.95E-07 3.36E-06 63 192 "SYN3,ABHD6,SLC12A5,ADORA3,BIN1,CDC42BPA,APBB2,APP,ARHGDIG,DNAH17,AZGP1,BMP7,LHX2,ZFYVE9,TPP1,CNR1,AKAP6,VCAN,RIPOR2,RIMS3,DSCAM,PHC2,FAM13A,MBNL2,SORBS3,EPHB1,FER,CAMSAP1,FOXG1,FLT1,PDLIM5,NSG1,LILRA2,KLF12,KCNJ5,MEF2C,AFDN,CD200,OPCML,PDE4A,PFKFB2,PLCD1,SLC25A23,MTRF1L,PMP22,LRRN3,PROX1,PTPRN2,RGS3,TTLL7,SEMA6D,ITSN1,SLN,RIMS1,SPTB,TMOD1,RBFOX2,RUNDC3B,FLRT2,BEST1,SLC13A3,ZBTB16,KCNAB1" Drug 6684_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.00E-09 1.47E-04 2.95E-07 3.36E-06 63 192 "KIDINS220,AMH,PPFIA4,GAS7,AQP4,ARHGDIG,ATP1A3,ATP2B2,ADGRB2,NRP2,LDLRAD4,CRLF1,CACNA2D2,CHN2,CLCN4,AKAP5,MICAL2,SUSD5,VCAN,MFAP3L,DTNB,EDN3,EFNA3,TNK2,EFS,TUBB4A,CORO2B,FGFR1,AGAP2,DPYSL4,GAB1,SIGLEC8,GLUL,GPR22,GRM8,SOX21,SHISAL1,KCNB1,KCNC1,LAMA2,SMAD9,MDM4,MSI1,MX1,MYH3,NCAM1,DCHS2,TCP11L1,ANKRD6,PKNOX2,SLC6A9,OGDHL,TNIK,ZHX3,SPTB,DOCK9,RALYL,PCDHA5,TLR4,TMOD1,TNS1,STMN4,SENP7" Drug 6388_UP Orlistat; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.00E-09 1.47E-04 2.95E-07 3.36E-06 63 192 "ARID1A,KIAA1324,MRTFA,AMPD3,APOC1,CDK10,PDE8B,ATM,SYNJ1,BAIAP3,CD86,CBFA2T2,CLTB,COL9A3,CSF1R,PYGO1,DAPK3,SMG7,EXOG,ETV1,EYA1,REEP2,CAMSAP1,DCTN2,DENND2A,SIGLEC8,CPLX2,POLL,GNAS,GRIA4,GRM7,GRM8,IRAK3,ICA1,ITIH2,KCNB1,MAP2,MMP16,MSI1,DDX25,NF1,NPPA,C19orf57,MINDY2,PPP5C,PRKAR1B,PRKCB,RNASE1,ZNF671,PKNOX2,SLC11A1,PDZRN3,UNC5B,MCF2L2,NPAS3,NACAD,SYT11,PLCB1,TRIO,AMACR,HIRA,FLRT2,ZNF154" Drug 2571_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.20E-09 1.57E-04 3.14E-07 3.57E-06 62 188 "ADORA3,AMH,BIN1,APBB2,N4BP2L1,MYRF,CFAP410,CACNA2D1,PTBP2,USP2,CRLF1,ZFYVE9,CLCN4,CRY2,SLITRK5,DZIP3,RUBCN,EDRF1,RIPOR2,MFAP3L,EDNRA,PHC2,EFNA3,FAM13A,EGR3,LPAR6,C3orf18,TBC1D16,PTK2B,FGR,CAP2,GPR153,ZNF276,RND1,GPD1,PCLO,GSN,KLF12,TJAP1,NDUFA5,NEK1,FSD1,CNNM2,MARCH1,RFX2,MYH14,SLA,SLC11A1,IZUMO4,SPTB,TROVE2,SAMSN1,ACSBG1,SYNE2,ARHGEF9,CRTC1,HIF3A,TMOD1,PIK3R5,RBFOX2,ZMYND8,ZBTB16" Drug 4739_UP Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ALCAM,APBA2,APC,APOC1,CDK13,MARK4,RAB33A,NECTIN3,CNTNAP2,DCAF4,TMCC2,DTNB,ELAVL3,KCNMB2,IGSF6,PTK2B,DLC1,DLL3,GAD2,ARPP21,GAP43,GATM,SRCAP,C1QL1,MALT1,GLS,GRK4,ADAMTS13,ICA1,TJAP1,KCNH2,KCNMA1,VWA5A,SMAD1,MAPT,ADAM22,TAGLN3,NF1,OPRL1,KCNK10,PCSK5,ST8SIA5,ENOX1,RGS3,RPS6KA2,SCN8A,RASA3,FUZ,LIMS2,SNAP25,SNCA,ZNF415,PEG10,RBM26,TROVE2,JMJD6,TNS1,TPM1,TRPM2,TTPA,SYNC,SLC30A3,ITM2C,EPM2A" Drug 6776_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "SEMA6A,BIN1,APC,APOC1,PPFIA3,CDK13,MARCH3,ATP6V0A1,SYNJ2,CAMK2B,FOXN3,RAB28,AKAP7,CRY2,ARHGEF10,EDRF1,DNM2,DTNA,CNNM1,SORBS3,ING4,ELAVL3,KIAA1109,FHL1,GPR153,HBS1L,RAB30,HTATSF1,GNG4,GPD2,NR3C1,GSN,KCNJ3,MAPT,LYRM9,SLC25A23,LRP12,FA2H,PEX5,RAD52,ZDHHC14,NEK11,SBF1,ZNF821,SPATA7,ZCCHC24,TSPYL2,LHPP,NXT2,NCDN,PLCB1,ARC,ASTN2,EXOC7,IQCE,TNS2,AHCYL2,UBTF,PLPPR2,SPHK2,REEP1,MAP3K12,SEMA3B,MPPE1" Drug 3511_UP Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ADRA1D,ADRA1B,PLA2G6,AMPD3,DNAH17,LDLRAD4,CFAP410,SEPT7,FOXN3,CHM,TCEAL2,CSF1,NCAN,PHF14,RASSF2,DAPK1,SPOCK2,DBT,SORBS3,FGFR1,FOXG1,FYB1,GALC,GCK,ALDH1L1,GLS,GPM6A,ATF7,GRB10,ICA1,C2orf72,IL6R,KCNB1,KCND3,KCNH1,VWA5A,SMAD1,ADAM22,ZNF862,NOVA2,PCBP3,CLDN11,PDE3B,PACSIN1,GON4L,WDR25,MYH14,SCN8A,ST6GAL1,SLC1A7,PEX26,BTBD7,KDM4B,ZC3H13,ARHGAP26,AJAP1,JMJD6,ATP11A,KIAA1107,TRPC1,WIPF1,ZFP37,ZIC3,MVB12B" Drug 3777_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "MRTFA,APBB1,CDK10,MARCH3,ADAM23,C5,ARHGEF1,SCARB1,NRXN3,HAPLN1,PDE4DIP,EDRF1,RIMS3,DAPK3,ARMCX2,MFAP3L,PLPPR4,ATN1,TOM1,PLXNC1,TUBD1,CDKL3,ETV1,ATP8A1,FOXG1,EFCAB2,PRELID3A,OGA,GAD2,DISC1,ATP8A2,INPP5K,GCNT2,GFER,GPM6B,TDRKH,VWA5A,NELL2,NF1,P2RY1,PAK3,PRKAR1B,SNRK,ACSS3,RAD52,ROGDI,TCP11L1,SH3BP2,ASAP3,DZIP1,SLC4A3,ARHGEF40,THSD1,PHLDB1,ARHGEF9,TCF4,DNAH7,TIAM1,CDK20,SSBP2,SPHK2,SEMA3B,EPM2A,PHTF2" Drug 6367_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "FAM135A,OGT,ANK1,APC,ARRB1,DNAH17,ZSCAN18,SLC4A4,KALRN,CBFA2T2,STOML1,SULT4A1,CNR1,COL9A3,CSF1,CNTNAP2,CALY,RIMS2,SNPH,SPOCK2,HEPH,SPOCK3,SNX29,TENM1,OLIG2,ETV1,KIAA1109,OLFM1,FHL1,C1orf61,GAD1,ADAM28,GLYR1,KCNMB4,NXPH3,HRH3,C2orf72,KCNB1,SAMD14,SNTG1,PIK3CD,MAPK8,MASP1,RELN,FAM120C,KHDRBS2,SEMA6D,NTNG1,RPH3A,SLC2A5,ARHGEF40,SLC11A1,SHANK2,SNCA,NPAS3,PHLDB1,SYT5,PCDHGB6,PSD3,SLC35G2,TNS1,OSBP2,VAV2,LAT2" Drug 5948_DN rotenone; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ASPHD1,ADRA1B,KIDINS220,BEGAIN,GAS7,PPP4R4,DDX3Y,ALDH4A1,PROM1,CHGA,CHN2,LHX2,CREM,CSF1,PDE4DIP,CNTNAP2,CNIH3,MFAP3L,DLG3,ATN1,HIPK3,FCF1,EFNB3,EGFR,EIF5,NRN1,FGF1,CAMSAP1,SCARA3,GAB1,GART,SRCAP,GPM6B,TDRKH,GPR17,CNTRL,KCNN1,KIFC3,MAPT,AFF1,MMP17,P2RY13,OPRL1,CLDN11,PC,CDK14,PTN,PEX5,RAB3IL1,SH3BP2,BTBD7,OGDHL,KIF13A,KDM4B,ZC3H13,ARHGAP26,MAPK8IP3,PCDHGA10,NSD1,TIAM1,R3HDM1,TNS1,CADM1,OSBP2" Drug 2351_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ACTN2,NDRG3,APOC1,MARCH3,ALDH4A1,ATP1A3,NOL4,AZGP1,PROM1,BMP7,CACNA1A,REPS2,IQCK,MYRIP,CPS1,CREM,CRMP1,CSF1,DAPK3,SPOCK2,DCT,SV2A,EFNB3,TNK2,RASGRP2,ST3GAL6,ARPP21,SIGLEC8,WASF3,SRCAP,GNAL,GNG3,GRB10,GRM7,ATXN2L,ZNF862,NDP,NDUFA5,P2RY1,PDE1C,PDE4D,CDIP1,SYTL2,GDPD2,PTAFR,PEX5,ACSM5,TMEM206,FOXRED2,SCN3A,RASA3,NLGN1,ZNF365,KDM4B,SPTAN1,ATP10B,VAMP1,TACR1,DNMBP,SYNE1,DNAH7,THRA,RUNDC3B,SSPN" Drug 3076_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "AMH,CDC42BPA,APBB2,BCAS1,ALDH4A1,BMP7,GYG2,CACNA1I,HAP1,RUNX1T1,INA,CBFA2T2,REPS2,CHN2,CHRNA4,SLIT2,RAB33A,CNTN1,IQCK,ABI3BP,TCEAL2,NCOR2,CSF1,MICAL2,CNTNAP2,CTIF,MFAP3L,DSCAM,DYRK1A,EDIL3,CELSR3,FER,C1orf61,PRELID3A,ALDH1L1,ADAM28,POLL,GNAO1,MAP4,MMP16,MYO6,NPR2,PCBP3,MTRF1L,CEP41,RAD52,TCP11L1,ST6GAL1,SLC14A1,FAIM2,PALLD,WDTC1,HECW1,SPTAN1,SEPT8,ZFR2,SYT5,POPDC3,WSCD1,ICAM5,CHST5,ZKSCAN5,RPRM,ZIC3" Drug 2263_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "AK2,ALCAM,TRMT9B,CDC42BPA,GAS7,CADM3,CACNA1I,BAIAP3,CDH2,KCNAB3,ZFYVE9,CPS1,CSF1R,GREB1,ARHGAP24,DAPK1,DCT,SRGAP3,DTNB,MBNL2,SRPK3,VPS13B,ABCA8,DLC1,FGFR1,OGA,ATP8A2,GLS,ATF7,PCLO,GRIN2C,GRM7,GUCY1A1,KLF12,KIF5A,MOBP,NNAT,NTRK2,MTRF1L,PDZRN4,CDIP1,SAMD9,RAD52,RGS12,KLHL11,SATB1,SH3BP2,PPP1R9A,NLGN1,PKNOX2,SLC14A1,COA1,DOK5,HECW1,NPAS3,MAPK8IP3,JMJD6,TAC3,WSCD1,TEX15,CHST5,FLRT2,ADAMTS9,SMIM8" Drug 2798_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "NDRG2,ADD2,KIAA1324,ALCAM,SEMA7A,APAF1,PDE8B,MARK4,RASL11B,ALDH7A1,CAMK2G,CDO1,ASIC3,RCHY1,TCEAL2,DCAF4,NOS1AP,TRAPPC9,ATN1,DUSP9,HIPK3,DMTN,STX2,FGF12,CAMSAP1,IQCG,PDLIM5,CAMKK2,DLL3,OGA,GAD2,SRCAP,RND1,GLS,MSL3,ICA1,MAP4,MMP16,ADAM22,NELL2,KCNK10,PCDHGC3,SLC25A23,LRP12,RETREG2,RGS4,RGS12,SBF1,RASA3,SH3BP2,PPP1R9A,ASAP3,DOCK10,CDK19,ZBTB43,POPDC3,KIAA1107,TBCEL,WSCD1,PCDHA5,LAT2,STMN4,SEMA3B,KAT6A" Drug 2324_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ADORA1,PLA2G6,ALCAM,TRMT9B,AMH,BIN1,CDC42BPA,APC,RASL11B,ATP2B2,CFLAR,SGCE,CAMK2B,HIP1R,ARHGAP33,LHX2,CRYM,SNCAIP,RIMS2,SEC14L5,TMCC2,ERCC2,OLFM1,FGFR1,FGR,GAB1,SRCAP,RUNDC3A,STON1,NR3C1,PTGDR2,SCRG1,INPP1,KCND3,LSS,MAOB,MGAT3,ADAM22,NEFH,EPN1,MTRF1L,MAPK8,PTPRB,RGR,RGS12,GSTCD,SCN2B,BCAN,SLC2A5,PKNOX2,SORCS3,ZNF423,ZBTB43,INKA2,POPDC3,PSD3,PCDHA5,THBS4,ZMYND8,VIPR2,LAT2,KCNK12,KCNAB1,NUP214" Drug 5069_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "AQP4,PRX,ATP1A3,B3GALT2,CADM3,ADGRB2,RGS9,BAIAP3,LDLRAD4,CFAP410,HAP1,RUNX1T1,CD86,CBARP,CHN2,WHRN,CSF1,BRINP1,DCT,DTNB,AASS,ELAVL3,MTSS1L,FGFR1,AGAP2,TBR1,FYB1,LYVE1,TOX3,GRIN1,GRM7,ATXN2L,IGF1,KCNH2,KCNJ5,PACRG,AFDN,NNAT,NPPA,PDE4B,PDGFRA,RETREG1,PKN2,GRAMD1C,PTPRH,PID1,RASGRF1,KCTD17,TMEM206,FRMPD1,BCAN,SLC15A2,KDM4B,SOX2,PHLDB1,SYP,TBCEL,TPM3,CHST5,VGF,LAT2,ZNF74,PARP6,SEMA3B" Drug 4000_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "RALGAPA1,ADD2,ADORA1,NME5,ALK,AMT,SEMA7A,PPFIA3,MADD,CDK13,ADAM15,FUBP1,BAIAP3,CBFA2T2,SCARB1,TPP1,MYRIP,ENTPD4,CRY2,PDE4DIP,PHF14,SEC14L5,DTNA,HIPK3,SRPK3,EPHA5,SPEG,ETV1,OGA,GAD2,HLF,IL12A,KCNJ3,KHK,KIFC3,MDM4,MMP16,NF1,PURG,PPARA,PKN2,MAPK10,ELOVL2,PTPRN2,BEND5,GAL3ST4,RGS4,RPS20,SH3BP2,SNCA,KIF13A,TNIK,PHLDB1,VAMP1,MCF2L,EXOC7,TNS1,TPM1,TRPC1,ZNF24,WNK1,PARP11,PHTF2,DPF3" Drug 4239_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ACTN2,ADRA1D,PPP4R4,CCDC181,N4BP2L1,ATP6V0A1,ADGRB1,ARHGAP33,TAOK2,ARHGAP22,SLC22A6,ZFYVE9,VAX2,CNTN1,CSF1,CHD5,CNTNAP2,RIMS3,MAML1,DBT,SV2B,SRGAP3,ATN1,NCALD,ETV1,REEP2,PTK2B,DCTN2,GALC,RND1,GNG4,STON1,GRIA1,GRIK5,CACFD1,SCIN,ITIH2,KCNA2,KCNJ3,KIT,VWA5A,SMAD1,ADAM22,MSR1,NPPA,NTRK2,MAPK8,CNNM2,GDPD2,PTPRH,PBRM1,RYR1,LRRTM4,SLCO1A2,TNIK,NFASC,MAPK8IP3,ACSBG1,MLC1,SEMA4A,OBSL1,TNS1,UCHL1,PDIA2" Drug 3621_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "AGT,PPFIA3,ASCL1,MARK4,GYG2,CFAP410,CACNA1D,CDH2,CLCN4,ABI3BP,CREM,AATK,NCAN,RIMS3,SPOCK2,DBT,DCT,ZNF804A,PARD6A,SRGAP3,ATN1,EDN1,EFNB3,FAM13A,RASGRP2,ERCC2,PIPOX,AFF2,GAD2,GPM6A,GRIK1,PTGDR2,IL11RA,KCND3,KCNK2,NPR2,NPTX1,SLC11A2,KCNK10,CDK14,PLCD1,PPARA,PKN2,RASGRF1,KLHL11,SYNDIG1,RYR1,RASA3,FRMPD1,SLC11A1,LIMCH1,CAND2,ACSBG1,SYT11,ARC,ROBO3,TCF7,TRIM2,PCDHGA10,TEX15,ZFPM2,CRB1,TRO,MVB12B" Drug 6015_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "APBA2,APBB2,APOC1,SEMA4G,MARK4,BRINP2,CFLAR,GYG2,CACNA1I,CFAP410,CACNA1D,HAP1,NEURL1,KCNAB3,TAOK2,ZFYVE9,CRMP1,CRY2,PDE4DIP,NOS1AP,HIPK3,SIDT2,TNK2,COQ7,KCNMB2,FHL1,FOXG1,OGA,GAB1,SRCAP,ATF7,NR3C1,GSN,GSTM5,ATXN2L,HPSE2,IRF8,KCND3,KCNJ3,AFDN,NF1,CLDN11,PFKFB2,DUSP26,PLCB2,LRP12,GRAMD1C,PTPRN2,WLS,KIF16B,ST6GAL1,EPN2,SLC6A11,DOK5,UHRF1BP1L,POPDC3,KIAA0930,AP4E1,HEY1,SEZ6L,METTL3,TRPM2,WIPF1,LAMP5" Drug 6091_UP Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "NDRG2,ADORA3,C1QTNF1,ADGRF5,SEMA7A,APOC1,SPTBN4,N4BP2L1,SCAPER,BAIAP3,LDLRAD4,CALB2,CAMK2B,CBARP,CNTNAP2,NOS1AP,DBT,EBI3,HSD17B14,LRRC23,ZNF589,CAMSAP1,FHL1,GABRA2,CSDC2,RUNDC3A,PRUNE2,GPR22,GPER1,GRIK5,HRH3,ATXN2L,ITGA7,KCNH1,KCNH2,LAMA2,LSS,MAP4,KITLG,MN1,ZNF862,PCDH9,PLXNB1,MAPK8,SALL1,ASAP3,SLC2A5,ARHGEF40,KDM4B,SPTAN1,COLGALT2,RGL1,AJAP1,ATP11A,DMXL2,DOCK9,TNS2,TNS1,OSBP2,FLRT1,LAT2,CA10,MVB12B,AP3B2" Drug 4229_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "TTYH1,ABAT,KIDINS220,NR0B1,ARHGDIG,ASCL1,SLC4A4,N4BP2L1,CACNG1,CAMK2B,DLGAP1,CHN2,NRXN2,DNAJB5,CSF1,SUSD5,NOS1AP,DBT,DCC,MFAP3L,SRGAP3,ST8SIA3,EDNRA,LRRC23,EPHB1,PIPOX,CACNG2,EFCAB2,GABRA5,GALR1,SIGLEC8,GNAL,PRUNE2,ADAMTS8,GRM1,HTR5A,ICA1,KCNC1,MAN2A2,ADAM11,ADAM22,MYH7,NCAM1,NEFM,NEUROD1,ABCB1,PHKG1,DCHS2,C1orf54,RGR,KLHDC8A,SCN2B,SLC8A2,DOP1A,HECW1,VAMP1,SYT5,ADGRL3,TIMP4,CADM1,BEST1,PRDM2,CAMK1G,GAN" Drug 3881_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ADRA1D,PLA2G6,C1QTNF1,AMH,CNTNAP1,APAF1,APBA2,KCNAB2,BACH1,ADGRB3,CACNA2D1,CDC42,DCLK1,CHM,CHRNB2,COL9A3,TCEAL2,DTNA,EDNRA,FAM13A,DMTN,KCNMB2,CDHR1,NRN1,DLC1,FGFR3,PDLIM5,CAMKK2,CSPG5,SEPT9,PCDH17,GNAL,PRUNE2,PCLO,ADAMTS13,KLF12,ICA1,TJAP1,NCF2,NFIX,PCBP3,OLR1,CDK14,PIK3CD,CDIP1,TTLL7,KCNIP1,CLIP1,ITSN1,SH3GL3,SLC6A9,ARHGEF40,CXXC4,KDM4B,AJAP1,TCF4,DOCK9,CRTC1,TMOD1,TPM3,TRO,TTPA,SLC30A3,SLC17A7" Drug 3357_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ARID1A,ADORA1,KIDINS220,NME5,AMT,GAS7,CDK13,CACNA1G,CAMK2B,HIP1R,RUNX1T1,CNN3,PICK1,SPOCK2,ATN1,DYRK1A,EDNRA,AASS,ELAVL3,LRRC17,SPEG,F3,OLFM1,FHL1,AFF2,KHDRBS3,HBS1L,LYVE1,GNAS,GRM1,TJAP1,INPP5B,KCNH2,MAG,MEF2C,AFDN,MOBP,CD200,NEUROD1,NFIX,SNTG1,PDE3B,PLTP,C19orf57,SAMD9,PLPPR1,ENOX1,MYH14,CARF,STK32B,SH3BP2,ASAP3,SLC11A1,SLC14A1,SMARCD3,WDTC1,DOK5,CAND2,ARHGAP26,TAC3,WSCD1,TTPA,ITM2C,NLRP3" Drug 5915_UP rotenone; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "ABHD6,KCNAB2,MARK4,CHRD,SLC4A4,ADAM23,BACH1,CACNA2D1,CALB2,HIP1R,ARHGEF2,SEPT7,CLTB,MYRIP,NECTIN3,RABGAP1L,HS3ST2,EFNA3,EFNB3,PLXNC1,ING4,TUBB4A,KIAA1109,FLNC,SORBS1,RND1,RAPGEF1,GRIK5,IL1RAPL1,PTGDR2,TJAP1,KCND3,MAN2A2,MDM4,MYO7A,NNAT,NOS1,NUMA1,CLDN11,PLCD1,MAPK8,MAPK10,RELN,RAB3IL1,TTLL7,RPS6KA2,MRAS,ZKSCAN3,EMC1,SPP1,ATP10B,SEMA4A,TBCEL,RIMBP2,TNS1,TRO,UBE3A,VGF,WIPF1,SYNC,SLC17A7,KCNAB1,UBE3B,SSPN" Drug 3350_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "NDRG2,AP2A2,NME5,APBA2,GAS7,FAM131A,AQP4,ASCL1,SLC2A11,CFAP410,RUNX1T1,CBFA2T2,CDH8,CHRNB2,COL9A3,KLHL3,EFNB3,MBNL2,ERCC2,F3,ZNF589,KIAA1109,FGF12,EFCAB2,GAB1,GABRA2,CPLX2,SRCAP,PCDH17,GPER1,NR3C1,TJAP1,KCNJ4,KCNMA1,KCNQ3,SMAD1,MYT1,KCNK10,PCDH9,CDK18,PDE3B,PIK3CD,EPN1,PLTP,PACSIN1,CNTLN,ZSCAN32,RAB3IL1,TRIM68,KCNIP1,SMPD3,SH3BP2,ASAP3,SLC1A2,SLN,SMARCD3,LIMCH1,ARHGAP26,RBM26,MAPK8IP3,GPR161,TLL2,DAAM2,SPHK2" Drug 5089_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.53E-09 1.73E-04 3.31E-07 3.77E-06 64 197 "CDC42BPA,GAS7,APOC1,AQP4,BRINP2,ALDH4A1,ATP2B2,CACNA1G,LDLRAD4,CA4,CACNA2D1,CACNG1,CAMK2B,USP2,SLC16A4,CD86,KCNAB3,CRLF1,TAOK2,CLTB,COL9A3,AATK,CSF1,CTIF,RASGRP2,CDKL3,FGF1,SIGLEC8,LPAR4,GRM5,ITGA7,KCND3,PACRG,AFDN,NELL2,PFKFB2,LRRN3,PKN2,MAPK7,GRAMD1C,RAD52,ZCWPW1,RGS10,PBRM1,FBXW7,SCN2B,SH3BP2,ST8SIA1,SORCS3,SOX2,HECW1,ASTN2,TACR1,MCF2L,RPGRIP1L,DOCK9,TLL2,WIPF1,ZIC3,SPHK2,TFIP11,SLC30A3,MVB12B,FAM13C" Drug 7407_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.60E-09 1.77E-04 3.37E-07 3.84E-06 60 180 "ADD3,NME5,APLP1,ARNTL,MARK4,ST3GAL5,SCAPER,NECTIN3,AKAP12,DZIP3,KIAA0513,RIMS3,ARMCX2,DNAJC6,ATN1,TSPAN5,EFNB3,PHF20L1,MRNIP,RASGRP2,TESK2,DPYSL4,NBEA,FYN,RAB40B,STON1,RNFT2,KCNH2,KIF5C,MAP2,MPP2,MXI1,PCDH9,SERPINE2,SERPINI1,MBOAT7,PRPH,CNNM2,PTCH1,RAB3A,SH3BGR,SH3GL3,FAM214B,SMARCD3,ZCCHC24,ELOVL4,CEP68,TTBK2,RGL1,STXBP1,ACSBG1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,DNAJC12,MAP3K12,SLC17A7,IFT88" Drug 4477_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-09 1.85E-04 3.52E-07 4.00E-06 63 193 "APAF1,APBB2,CDC14B,ARRB1,ARSE,CDK13,BRINP2,ATM,ATP1A3,NRP2,CFLAR,CBS,ADGRG1,NRXN3,ABCG2,RAB26,HOMER3,WHRN,COL9A3,AKAP5,NCOR2,CSF1,CNIH3,DUSP9,SEMA3D,TENM1,ELN,ZNF391,ETV1,KAT8,C1orf61,FAM49B,ZNF44,SRCAP,GPER1,CNTRL,GRIK5,JAK2,KCNN2,SMAD1,ADAM22,PDE4B,GPR85,EPN1,MINDY2,MAPK7,SNRK,ELOVL2,PTPRB,CCDC40,RFX2,RGS3,KCTD17,ROM1,SLC11A1,DOK5,ZHX3,ACSBG1,EXOC7,TBL1X,TNS1,TRO,KCNAB1" Drug 3715_UP Delcorine; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.78E-09 1.85E-04 3.52E-07 4.00E-06 63 193 "ACTN2,ADD2,ANK1,APBB1,EPB41L5,DNAH17,NRP2,BMP7,CHI3L2,JAM2,TAOK2,AKAP5,CREM,LRIG1,VCAN,DAPK1,SPOCK2,DCT,MAGI2,DMPK,DTNA,FCF1,SEMA3D,MBNL2,NCALD,ZNF549,CDHR1,KAT8,KIAA1109,C1orf61,GAD2,HBS1L,GAP43,GNG3,GPD2,GRM1,SOX21,ATXN2L,KCNJ5,KCNQ3,CD200,ADAM22,SLCO1C1,NNAT,NPTX1,NTRK2,DDR2,OPCML,PDE4D,SEMA6D,RASA3,HKDC1,CNKSR2,SLC1A7,RBM34,SCN3B,ZHX3,ZSWIM8,TRIM2,GPR161,UCHL1,WIPF1,KAT6A" Drug 7341_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.78E-09 1.85E-04 3.52E-07 4.00E-06 63 193 "NDRG3,ADORA2A,FAM131A,BAIAP3,KALRN,ASIC3,CLTB,FADS2,CSF1,CSF1R,PDE4DIP,TBC1D5,GIT2,RABGAP1L,ATN1,DSCAM,MBNL2,ING4,EZH1,ZNF589,CAMSAP1,C1orf61,PRELID3A,GAB1,GAD1,ZMYND11,ERAP1,MALT1,RAB30,STON1,GRB10,RASSF8,HSF2,TJAP1,MEIS2,NOS1,CNOT4,PDE1C,PDE3B,PLXNB1,ZSCAN2,RGS3,SYNDIG1,FOXRED2,SAFB,ZNF821,FUZ,CNKSR2,SLC22A4,WDTC1,ZCCHC24,ERC1,SPTAN1,CDK19,MAPK8IP3,PLCB1,WSCD1,ARHGEF12,TGFBR3,ZNF34,TRPC1,ZNF24,EPM2A" Drug 6820_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.81E-09 1.87E-04 3.53E-07 4.01E-06 59 176 "ADD3,ALAD,APLP1,ST3GAL5,RAB29,CLGN,CLCN4,NECTIN3,AKAP12,PDE4DIP,RIMS3,ARMCX2,DNAJC6,EFNA3,EFNB3,RASGRP2,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,STON1,MXI1,NAP1L3,NEK1,PDE4A,TMOD2,SERPINE2,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,PTCH1,GAL3ST4,RPS6KA2,SH3GL3,ASAP3,CPEB3,SYBU,WDR47,FAM214B,CCDC88A,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 6972_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.81E-09 1.87E-04 3.53E-07 4.01E-06 59 176 "ADD3,NME5,APAF1,MARCH3,BMP7,ST3GAL5,SCAPER,RAB29,CLGN,AKAP12,ARHGEF10,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNA3,EFNB3,MBNL2,STX2,DPYSL4,FYN,GLS,RAB40B,STON1,DIPK1A,INPP5B,KIF5C,MAP4,MAPT,MPP2,MXI1,SERPINI1,PIK3CD,PKIA,PRPH,PTCH1,RAB3A,FBXW7,SH3GL3,ZNF365,WDR47,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,TACC1,MCF2L,TRIM2,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,ZNF45,REEP1,ITM2C" Drug 4565_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.81E-09 1.87E-04 3.53E-07 4.01E-06 59 176 "ABAT,ADRB2,MTUS1,ARNTL,ADGRB2,ST3GAL5,HAP1,HIP1R,USP2,REPS2,CHN2,ABCG1,PDE4DIP,CNTNAP2,CTH,KIAA0513,DNAJC6,PLPPR4,PTK2B,TAOK3,ATP8A1,TESK2,BAIAP2,DPYSL4,SORBS1,PDLIM5,PNMA2,FYN,RND1,GLS,SCIN,DIPK1A,ITGA7,KIF5C,MMP17,TAGLN3,PDGFRA,SERPINI1,RETREG1,PRPH,PTCH1,PTPN13,RGS4,FBXW7,SH3GL2,SH3GL3,TNIK,FNBP1,BEX1,THSD1,RGL1,SYT1,COBL,KIAA0930,TGFBR3,RUNDC3B,DNAJC12,TRIM9,PLSCR4" Drug 7380_UP Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ABAT,CDC42BPA,KCNAB2,EPB41L5,SHROOM2,AQP4,PDE8B,ATP1A3,ATP6V0A1,BTRC,CACNA2D2,DNAJB5,NCOR2,ARHGEF10,SDC3,KIAA0753,DPH1,DRP2,ATN1,EDN1,IRAK4,COQ7,FER,FGF13,ERAP1,ALDH1L1,GNG3,GPM6B,SPACA9,GRM1,HNMT,HSF2,SHISAL1,KCNN1,ADAM11,MGAT3,MOBP,NF1,CLDN11,PLCD1,PPP5C,GDPD2,WDR25,PTCH1,RAB3A,RGR,FBXW7,TRAPPC13,ASAP3,ARHGEF40,SLC20A2,TNIK,POGZ,ST5,PHLDB1,VPS13A,SYT1,ASTN2,DOCK9,RBFOX2,CADM1,KCNAB1,UBE3B,NLRP3" Drug 6025_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "TKTL1,AGT,LTBP4,BIN1,PLA2G4C,PDE8B,N4BP2L1,AZGP1,ADGRB2,CACNA1I,CACNA1G,CFAP410,CAPN3,HIP1R,CBARP,EPS15L1,CPS1,CNTNAP2,RIMS3,RUSC2,SV2A,SRGAP3,SHANK1,ATN1,HSD17B14,ERCC2,PIPOX,CEND1,REEP2,EFCAB2,NSG1,GAP43,ERAP1,GNAS,LILRB4,GPER1,STMN2,KLF12,HLF,ITIH2,AFDN,DDX25,NTRK2,KCNK10,CAMKV,EPN1,POU3F4,LRRN3,PTPRB,FAM120C,KHDRBS2,TMEM206,RYR1,ASIC4,ZFP2,SLC1A7,SLC11A1,COLGALT2,TACR1,AMOT,PRDM10,HRASLS,CAMK1G,NLRP3" Drug 4301_UP Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "SPARCL1,PKP4,APBB1,APBB2,AQP4,AQP6,PTCH2,N4BP2L1,NRP2,CFAP410,SLC16A4,SCARB1,SRSF11,STOML1,DNAJB5,SUSD5,CTNND2,CTIF,ATN1,EDN1,MBNL2,MRNIP,KCNMB2,REEP2,ST3GAL6,FGF12,AGAP2,SORBS1,TBR1,RUNDC3A,GPR17,KLF12,IL6ST,KCNQ3,KIF5A,KIFC3,AFF1,CD200,ADAM22,NEK1,NELL2,PDE4D,CAMKV,EPN1,STRN3,LRP12,POU6F1,DZIP1,SLC15A2,SCN3B,SOX10,NPAS3,TROVE2,SYN2,COBL,TCF4,TK2,TMOD1,TMPO,ZMYND8,FLRT2,LAT2,WNK1,EPM2A" Drug 5663_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ACTN2,ADORA2A,APBA2,PPP4R4,ARHGDIG,HAP1,CAMK2B,CHI3L2,STOML1,CPS1,CNTNAP2,CDON,SHANK1,ATN1,DSCAM,EDNRB,SGK2,DLC1,FGFR1,AFF2,DCTN2,GPR153,GAD2,ERAP1,GPM6A,NR3C1,ICA1,INPP5B,KCND3,KCNH2,KCNMA1,VWA5A,AFDN,MMP16,NF1,CNOT4,NPTX1,P2RY1,PDE1C,PFKFB2,RETREG1,CDIP1,C19orf57,LRRN3,GDPD2,PTX3,CEP97,ZMAT4,SH3BP2,MAPKBP1,PDZD2,ZC3H13,CLSTN2,AJAP1,SLC35G2,TEX15,TLR4,PIK3R5,VLDLR,SLC30A3,NT5M,SLC17A7,MVB12B,SSPN" Drug 601_UP MK-886; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "BRAP,MTUS1,CDC14B,KIAA1614,SEMA4G,HAP1,CD86,SCARB1,PICK1,CNTFR,AATK,ARHGEF10,NCAN,DGKG,C2CD2L,KLHL3,DTNA,DYRK1A,SUGP2,MBNL2,HSD17B14,KCNMB2,SPEG,ZNF589,AGAP2,TRMO,NSG1,SYT17,GSTM5,RNFT2,NCKAP1L,HMX1,KIF2A,STMN1,MMP17,MYH7,NACA,NNAT,NOS1,CNOT4,NPR2,NRGN,SETD4,PDE1C,PHKG1,PLXNB1,MAPK8,RALGDS,SUSD4,GAL3ST4,SCNN1D,SH3BP2,FERMT1,SLA,PREX2,KDM4B,ZCCHC24,CLSTN2,ARHGEF9,EHBP1,CHST8,LMF1,SLC17A7,UBE3B" Drug 2623_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "TRMT9B,AMPH,BIN1,APBA2,GAS7,MARK4,ASPH,ADAM23,GYG2,CA4,CAMK2B,ADGRG1,TAOK2,FADS2,NRG2,CSF1,PDE4DIP,SPOCK2,CTIF,MFAP3L,C2CD2L,GSDME,EXOG,SORBS3,ELAVL4,ELN,C3orf18,HSD17B14,VPS13B,RASGRP2,FAM198B,KIAA1109,GPR153,GABRG2,GCNT2,GLS,GSTM5,INPP5B,ITPKA,KCNK10,PCDHGC3,PTHLH,PTPRN2,FAM120C,RGS10,MYH14,SBF1,SHANK2,SMARCD3,KDM4C,ZC3H13,CLSTN2,ST5,SYT11,SMG6,SYNE1,AP4E1,TUBB1,VAV2,WIPF1,LAT2,ADAMTS9,SEMA3B,NUP214" Drug 4081_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "AMPD3,APC,ALDH4A1,KIF1A,CACNA1I,RAB28,CLCN3,DNAJB5,RAB26,TCEAL2,NRG2,CRMP1,NCOR2,ARHGEF10,VCAN,PDE4DIP,BRINP1,MFAP3L,RUSC2,SPOCK3,CDON,ATN1,CELSR3,EIF4G2,COQ7,MTSS1L,ZNF549,DLC1,ST3GAL6,SCARA3,SEMA4D,GAB1,SEPT9,GPM6B,LPAR4,GRM1,MGAT3,MOBP,NOVA1,NOVA2,SAMD9,ZSCAN2,RXRA,DOCK10,FNDC3A,NLGN1,PPP4R3A,BTBD7,ZNF415,RBM34,IQSEC2,LHPP,ATP11A,ROBO3,PCDHGA10,PCDHA5,TIAM1,CABIN1,ZMYND8,OSBP2,WIPF1,XRCC4,SCG2,TIGD6" Drug 5639_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ADD2,LTBP4,ALK,SYT13,CDC42BPA,ARHGDIG,ADGRB1,BAIAP3,KALRN,HAP1,TAOK2,RAB33A,CNN3,PICK1,NOS1AP,SNPH,SPOCK2,CTIF,DCC,HS3ST2,EFNB3,EGFR,C1orf61,DISC1,NEU3,AHDC1,C1QL1,POLL,PRUNE2,GRIK1,GRIK4,GRM1,HLF,KCNJ5,KCNN2,KIF5A,MEF2C,MID1,ZNF862,NOVA2,NPR2,PFKFB2,CAMKV,PLCD1,PLTP,PURG,RGS7,ASIC4,CNKSR2,FAM214B,PKNOX2,SLC11A1,LIMCH1,ZCCHC24,KIF21B,CLSTN2,MAPK8IP3,RGL1,SYT5,WSCD1,TCF7L2,TRPM2,AMOT,JPH3" Drug 3728_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "DPF1,ACTN2,ADD2,LTBP4,APC,BCAS1,PPP4R4,SYNJ1,HAP1,RUNX1T1,USP2,SYNGR3,CDO1,CHM,TAOK2,CLCN4,TPP1,STOML1,ABCG2,AKAP5,PLCH2,BRINP1,NTM,EXOG,SHANK1,ECM2,ABCC9,FCF1,SEMA3D,EGFR,REEP2,KIAA1109,GNAL,GNG3,PRUNE2,STON1,GRK4,NXPH3,IRF8,MATK,NF1,NOVA2,NTRK2,CLDN11,NLE1,RGS4,MYH14,FNDC3A,SLC1A2,RPH3A,ZNF334,RBM34,KDM4B,KDM4C,NFASC,LHPP,ATP10B,ARC,SLC44A1,CDK20,TRIO,TRO,WNK1,PRDM2" Drug 6503_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ACTN2,LTBP4,APBA2,ATP1A2,ADAM23,CA4,CAMK2G,RUNX1T1,ARHGEF1,DGKI,STOML1,CNTFR,COL9A3,MAML1,SPOCK2,KIAA0319,TMCC2,DTNA,ANKMY1,CAMSAP1,TPK1,ALDH1L1,RUNDC3A,PRRC2B,GPM6B,GPER1,PTPRT,SYNPO,ICA1,ITIH2,ITPKA,KHK,KPNA5,MAP4,NCF2,NEFM,NOS1,NPY,NOVA2,PFKFB2,PLCD1,FSD1,PTPRB,PEX5,RAB3A,RALGDS,RFX3,RGR,ROM1,MRAS,PPP1R9A,FRMPD1,ASAP3,PEG10,ARHGAP26,ATP10B,IQCE,ZNF34,SLC44A1,OSBP2,WIPF1,PRDM2,PLSCR4,NUP214" Drug 3827_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "NDRG2,ADD2,ADGRF5,LTBP4,APAF1,AQP4,PRX,ATP2B2,BMP7,CACNA1A,CACNA1D,HAP1,CAMK2B,RUNX1T1,USP2,CHI3L2,B4GALT6,CNTN1,CTNND2,MAGI2,ABCC9,EDIL3,EDNRA,ING4,LRRC23,IGSF6,ETV1,EZH1,KIAA1109,EFCAB2,GLYR1,RAB30,GPR17,SOX21,PTGDR2,KLF12,JAK2,KCND3,VWA5A,KITLG,AFDN,NF1,GPR88,PDE2A,RETREG1,NECAB2,SPATA6,POU6F1,WDR25,PTAFR,RASGRF1,ZMAT4,RYR1,FOXRED2,SLN,KIF13A,VAMP1,PLCB1,TAL1,TK2,HEY2,BEST1,XRCC4,PARP6" Drug 4225_UP Carcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ACHE,NR0B1,PKP4,GAS7,CDC14B,NRP2,SYNJ2,GYG2,CACNA1I,INA,NEURL1,CHGA,NRXN3,COL9A3,CSF1,FEZ1,PLCH2,NCAN,INTS1,DCT,SRGAP3,EIF4G2,CALCRL,RASGRP2,EFS,CDHR1,BAIAP2,CAMSAP1,SIGLEC8,SYT17,GCK,PCDH17,RAPGEF4,GRIN2C,GSTM5,IL6ST,ITIH2,KCNJ9,MAP2,MOBP,MYL3,PFKFB4,PTPRD,PTPRN2,GAL3ST4,RGS10,PBRM1,MYH14,TCP11L1,NTNG1,ZHX3,ZC3H13,NFASC,PLCB1,ATP11A,PCDHA5,AP4E1,ZNF34,TNS1,ZNF225,KCNAB1,SLC17A6,EPM2A,JPH3" Drug 6722_UP Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "AMPH,PKP4,APC,NRP2,KSR1,SCAPER,CACNA1I,BAIAP3,CALB2,HAP1,CHI3L2,TAOK2,NRXN2,HOMER3,FAM149A,COL9A2,CRMP1,SUSD5,CNTNAP2,CTNND2,MFAP3L,NTM,DOCK2,ATN1,ST8SIA3,SIDT2,PLXNC1,LRRC23,EFS,F5,HBS1L,STON1,GRM8,GPR45,HNMT,INPP5B,ITGA7,KCNF1,LSS,MAN2A2,TM6SF1,MIA2,NEUROD2,SNTG1,PDE3B,PTN,GSTCD,KCNIP1,ZFP30,SH3BP2,FBXO11,SLC11A1,CAND2,ATP10B,PLCB1,SEMA4A,DOCK9,R3HDM1,TNS1,VIPR2,KCNAB1,FAM13C,NLRP3,GAN" Drug 6037_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ALK,TRMT9B,AMPD3,ANK2,CNTNAP1,SLC4A4,ALDH7A1,AZGP1,GYG2,CDH2,CLGN,STOML1,DNAJB5,SULT4A1,WHRN,SNCAIP,CNTNAP2,RIMS2,CYBB,ATN1,ZMYND10,ZNF589,ADAM28,GFER,RUNDC3A,GNAO1,PRUNE2,GPM6B,FAM107A,NXPH3,HPSE2,KCNJ9,KIT,KITLG,AFDN,MOBP,ADAM22,NOVA1,PALM,RETREG1,EPN1,LRP12,LRRN3,KHDRBS2,RGS12,MYH14,CARF,DOCK10,NTNG1,SLC1A7,SMARCD3,WDTC1,SPTB,INKA2,MAPK8IP3,SYP,SEMA4A,WSCD1,ZEB1,DOCK9,HEY2,TPM1,NT5M,ADAMTS9" Drug 7320_UP Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "KCNAB2,APBB2,GAS7,ALDH7A1,MYRF,MYOM2,WHRN,SLC4A7,HAPLN1,ABCG1,CNTNAP2,HDAC9,TOX,SUGP2,MTSS1L,TBC1D16,FGF1,EFCAB2,FYB1,SYT17,STON1,SPACA9,IGF1,SCIN,MIA2,SCAMP5,MYH3,ZNF862,PAK3,PALM,PDGFRA,SLC25A23,PPM1B,MAPK7,APTX,PTN,TMEM231,RAB3A,TCP11L1,PAQR6,SAFB,SCG5,SH3BP2,AMBRA1,ST6GAL1,SLC14A1,ZNF415,SPART,MAPK8IP3,CEP68,JMJD6,TACR1,EXOC7,TCF7L2,CBX5,CABIN1,TNS1,TRPM2,WIPF1,WNT7A,XRCC4,SCG2,SEMA3B,KCNAB1" Drug 6983_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ABHD6,ADORA1,AP2A2,SRPX,MRTFA,APC,EPB41L5,BCAS1,CDK10,PRX,ALDH4A1,CFLAR,SYNJ2,BAIAP3,ARHGEF1,CHRNB2,CLU,AKAP7,NECTIN3,VCAN,DZIP3,EDRF1,GPRASP1,TBC1D5,GIT2,DBN1,DSCAM,PHF20L1,EIF5,ENO2,NCALD,ANKMY1,RRAGB,FECH,FHL1,DPYSL4,GABRA2,GAD1,HBS1L,ERAP1,GLS,POLL,HMGCR,INPP5B,KIF5C,LMO2,MEIS2,AFDN,MMP16,MPP2,PDPK1,FTO,LRP12,RELN,PTPRD,RIPOR1,GTDC1,RGS3,SBF1,PKNOX2,VPS13A,IQCE,ZNF74,MARCH8" Drug 2650_UP Androsterone [53-41-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ASPHD1,KIAA1324,PLA2G6,ALCAM,BEGAIN,DDO,PLA2G4C,MARK4,NUMB,ALDH4A1,BCL2L2,CAMK2B,CAST,ARHGEF1,ARHGAP33,WHRN,CREM,NCOR2,NOS1AP,ARHGAP24,C2CD2L,OPTN,ERBB4,ERCC2,EXTL1,FGFR1,SCARA3,INPP5K,GFER,RND1,PRRC2B,GPM6B,INPP5B,ITPKB,KCNF1,LMO1,MGAT3,BCO1,MX1,NOS1,ENPP2,NLE1,MBOAT7,PPARA,MAPK7,MAPK8,PTAFR,PTN,ZSCAN2,NKAIN1,RAB3A,RGS12,FBXW7,SLC11A1,MAPKBP1,WDTC1,ZCCHC24,SPTAN1,NPAS3,TCF7L2,TNS1,PDIA2,NDRG4,ITM2C" Drug 7519_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "MTUS1,MARCH3,STX16,MPDZ,CFLAR,MAGI1,TAOK2,CLCN3,CLU,DNAJB5,RAB26,NRG2,CHD1L,FAM131B,SPOCK2,DNAJC6,SMG7,EXOG,DMPK,ATN1,FEM1B,MBNL2,VPS26C,FHL1,ANKFY1,EFCAB2,SYT17,DISC1,GLYR1,HTATSF1,CACFD1,GUCY1B1,IL6ST,MBD1,MIA2,MN1,MX1,NDUFA5,NFYA,NUMA1,PALM,SERPINI1,PLXNB1,RAD52,BEND5,REV3L,RGS10,ATXN1,KIF13A,USP33,IQSEC2,ZBTB43,SYNE1,AP4E1,TK2,R3HDM1,TRPC1,ZMYND8,HIRA,LMF1,NSD2,WNT7A,EMSY,PHTF2" Drug 7386_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ABR,MTUS1,PLA2G6,BCAS1,SHROOM2,ATP2A2,ATP2B2,ADAM23,BACH1,CACNA1A,HAPLN1,USP6NL,CTIF,RUSC2,DLG4,FCF1,PLEKHO1,ETV1,RRAGB,CGREF1,SEPT9,POLL,LPAR4,GRIN2C,HSF2,SHISAL1,TJAP1,IL12A,DIPK1A,KCNC1,KCNJ5,MAN2A2,TAGLN3,CNOT4,NOVA1,SLC11A2,FA2H,POU6F1,LRRN3,PPP5C,TMEM231,ARHGEF10L,EMID1,ATXN1,SH3BP2,SLC20A2,ARHGAP26,SPTAN1,DDN,KAZN,SMG6,TCF7L2,PSD3,GPR161,R3HDM1,CABIN1,TRIO,ZKSCAN5,FAM155A,FLRT2,MICAL1,ZNF74,MPPE1,PARP11" Drug 5862_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "APC,ATP2A2,ST3GAL5,CAMK2B,RUNX1T1,RAB26,PCYT1B,ABCG1,RIPOR2,SPOCK2,CNIH3,HSD17B14,MTSS1L,REEP2,ZNF589,FGF1,ANKFY1,SEPT9,GPD2,CNTRL,GRM1,IGF1,TJAP1,ITGA7,KCNB1,KCND3,LIFR,MATN3,CNOT4,OLR1,RETREG1,LRRN3,CEP41,PROX1,PTPRD,PEX5,TMEM231,ACSS3,RAD51D,RAD52,C1orf54,RGS3,RGS4,RGS12,RYR1,ZNF821,ZFP30,SH3BP2,BCAN,NLGN1,SLC1A7,PKNOX2,SLC11A1,TSNAXIP1,SP2,ARHGAP26,SPTB,PCDHGB6,TEX15,TK2,PIK3R5,TPM1,HPS4,KCNAB1" Drug 251_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ASIC1,KDM5D,NME5,ANK2,APP,ASCL1,CADM3,HIP1R,ARHGAP33,B4GALT6,CHRNB2,LHX2,CNTN1,DPP6,SIDT2,EFNB3,EGFR,LPAR6,EIF4G2,COQ7,RCAN2,LRRC23,EPHB1,CDKL3,F3,FGFR1,FGFR3,GAB1,SRCAP,GLRB,LILRA2,GRM8,SOX21,ARHGAP19,IRF8,C2orf72,IGF1,KCNMA1,LAMP2,MAOB,MEIS2,NAP1L2,NELL2,NPTX1,MINDY2,CEP41,VPS13C,PTHLH,C1orf109,ROBO1,ITSN1,IFT122,SNCA,NMNAT2,SPP1,ZC4H2,KLHL7,NPL,PRMT8,UGT8,VSNL1,ZNF23,HPS4,MPPE1" Drug 6165_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "SLC12A5,ADORA1,TRMT9B,ANK3,SEMA7A,CNTNAP1,APBB2,PDE8B,CADM3,BTRC,HAP1,CLGN,CHI3L2,CREM,AATK,CSF1,ARHGEF10,MICAL2,CSNK1E,RIPOR2,RIMS3,DGKG,MFAP3L,TMCC2,DSCAM,OPTN,ELAVL3,F5,TBC1D16,BAIAP2,IQCG,SORBS1,GABRA5,GPR162,MSL3,PCLO,GUCY1A1,KCNB1,KCNJ5,MAP2,NPY,PDE4D,PFKFB2,RETREG1,PLCD1,EPN1,PRKAR1B,RELN,SH3BP2,SLC1A7,KANSL3,SLCO1A2,SNCA,PEG10,ZNF423,LHPP,ARC,SYN2,ZEB1,TMEM151B,PCDHA6,SLC44A1,SEZ6L,TRIO" Drug 1538_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ADORA1,SRPX,MRTFA,BEGAIN,AMPH,APOC1,MARK4,ATM,MTMR3,GYG2,CFAP410,NEURL1,CDO1,ASIC3,STOML1,QKI,HOMER3,ABI3BP,CRMP1,CSF1,DCAF4,ECE2,DOCK4,RIMS3,CTIF,BRINP1,ARMCX2,RABGAP1L,SIDT2,EFNB3,SPEG,DLC1,MSL3,ADAMTS13,IL6ST,KCNH2,MAN2A2,CD200,ADAM22,BCO1,CDK18,PPARA,MAPK7,PTN,BSDC1,EMID1,BTBD7,SLN,COA1,OGDHL,LIMCH1,TTBK2,AJAP1,TCF7L2,TRIM2,PSD3,CRTC1,TK2,TMOD1,HIRA,WIPF1,ZIC3,SLC17A6,EPM2A" Drug 3700_DN Merbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-09 2.17E-04 3.92E-07 4.46E-06 64 198 "ADD2,AGT,APBB1,APBB2,APOC1,SEMA4G,SLC4A4,MYRF,BTRC,CAST,ARHGAP33,CACNA2D2,TAOK2,FAM189A2,HOMER3,CNTN1,NCOR2,VCAN,SLITRK5,ATN1,DTNA,FAM13A,ELAVL3,LRRC23,FGF1,FGFR1,GABRA2,SRCAP,STON1,ICA1,SHISAL1,ITIH2,KCNB1,KCNJ5,KHK,VWA5A,MIA2,ADAM22,MYO7A,NF1,NFYA,NPR2,CLDN11,SNTG1,CEP41,PTN,ACSS3,ENOX1,KCTD17,MYH14,TCP11L1,SCN8A,DZIP1,PKNOX2,KIF13A,SP4,ARHGAP26,SPTB,THSD1,ACSBG1,RPGRIP1L,BHLHB9,RPRM,UBE3B" Drug 3880_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.74E-09 2.32E-04 4.17E-07 4.75E-06 63 194 "ARID1A,NDRG2,ADCY2,ADORA1,ADORA2A,ALCAM,FAM135A,EPB41L5,ASCL1,ASPH,ATM,GYG2,CACNA1I,LDLRAD4,CAMK2B,RHBDL1,CDC42,ZFYVE9,NMT2,CNTN1,FAM149A,CPS1,TMCC2,HS3ST2,DYRK1A,EGR3,ELN,SPEG,FGFR1,ANKFY1,KHDRBS3,DISC1,GFER,ATF7,GRIK5,ITPKA,JAK2,KIT,VWA5A,MAPT,KITLG,ADAM22,NELL2,CLDN11,PCDH9,POU3F4,MINDY2,SNRK,PTAFR,S100B,SLC4A3,SLC11A1,HECW1,ATP10B,ARC,TBCEL,TIMP4,HEY2,HIRA,UBE3A,EMSY,SLC17A7,KCNAB1" Drug 2764_UP Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.74E-09 2.32E-04 4.17E-07 4.75E-06 63 194 "NDRG2,KIDINS220,OSBPL1A,NME5,ANK1,PPFIA3,MARK4,ASPH,ATP2A2,ATP2B2,SYNJ1,ST3GAL5,SYNJ2,SCAPER,CACNA1I,CACNG1,HAP1,ARHGEF1,NEURL1,MYOM2,HOMER3,CSNK1E,DOCK4,RIMS3,DAPK3,PARD6A,KBTBD11,CDON,FAM198B,ACSL4,DLC1,SCARA3,KHDRBS3,GAD2,IL6R,KCNB1,MAPT,MYO7A,NF1,SLCO1C1,MTRF1L,ZDHHC14,GTDC1,RGS3,RYR1,FAM192A,SBF1,ZNF821,RASA3,FBXO11,PKNOX2,SLC6A9,ZCCHC24,CAMTA2,SYNE1,ARHGEF12,TEX15,HEY1,PDIA2,MICAL1,PRDM2,EPM2A,KAT6A" Drug 4260_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.74E-09 2.32E-04 4.17E-07 4.75E-06 63 194 "ABAT,ACHE,SYT13,AMPD3,DDO,ASCL1,SYNJ2,BAIAP3,USP2,ADGRG1,FOXN3,CHI3L2,NRXN3,TMEM59L,DNAJB5,FAM149A,CABP1,COL9A3,RGS6,CNTNAP2,TNK2,DLC1,ATP8A1,AFF2,SORBS1,SIGLEC8,GNAL,GNAO1,RAPGEF1,GRIK5,SOX21,GPR45,ATXN2L,KCNC1,LSAMP,PACRG,MOBP,ADAM22,NEUROD1,NF1,NTRK3,NUMA1,PDE3B,PDE4D,DUSP26,RASGRF1,KHDRBS2,GAL3ST4,ZMAT4,RNASEL,RYR1,RASA3,SLC1A6,SOX2,DDN,INKA2,ATP11A,PCDHA5,TF,TRO,KCNK12,PRDM2,PAK5" Drug 3071_UP Estrone [53-16-7]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.74E-09 2.32E-04 4.17E-07 4.75E-06 63 194 "ABHD6,KIDINS220,SYT13,APC,CDK13,DNAH17,ALDH4A1,BMP7,RUNX1T1,ZFYVE9,DNAJB5,TCEAL2,NRG2,CREM,CRY2,ABCG1,CRYM,SIPA1L1,PDE4DIP,DOCK4,DMD,DSCAM,DYRK1A,EFNA3,C3orf18,LRRC23,ETV1,PTK2B,DLC1,ATP8A1,FGFR1,SEC23B,C1orf61,PDLIM5,ALDH1L1,COPS8,GPM6B,GRK4,WIF1,HNMT,DHX35,TJAP1,MAP4,AFDN,MOBP,TAGLN3,MX1,NTRK2,OMG,OPRL1,PNMA3,CNNM2,PTK2,PTPRN2,FAM120C,ZMAT4,KCTD17,GALNT10,SH3BGR,NTNG1,ARHGAP26,IQSEC2,RAP1GAP2" Drug CID000005631 AC1L1KS5 Stitch 4.80E-09 2.35E-04 4.22E-07 4.80E-06 94 334 "ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,ADRA1B,AGT,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NFS1,CCK,KRIT1,LRBA,CACNA2D2,CHRM1,PLCXD3,BOC,DBI,SNAP91,ATN1,EDN1,EDN3,EDNRA,EDNRB,CACNG7,CACNG2,PPP1R1B,ATP2C1,GNAS,PLCD4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GPR45,PTGDR2,SCIN,KCNK3,MAG,KITLG,NPY,NPPA,OPRL1,OXTR,P2RY1,KCNK10,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,PLCD1,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,PSD,PTHLH,PTH1R,RYR1,RYR3,MAPK12,SLC2A5,SLC14A1,PLCB1,SYT1,TAC1,TAC3,AKTIP,TIAM1,TRH,TRPC3,NTSR2,VAV2,VIPR2,PLPPR5,PLD4" Drug 6784_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.84E-09 2.37E-04 4.24E-07 4.82E-06 59 177 "ADD3,NME5,SEMA6A,BMP7,ST3GAL5,RAB29,BAIAP3,CLGN,DNAJB5,DOCK4,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,ENO2,RASGRP2,STX2,FHL1,DPYSL4,SORBS1,FYN,CYP46A1,STON1,KIF5C,MPP2,MXI1,NAP1L3,NEK1,PDE4A,SERPINI1,PIK3CD,LRP12,GRAMD1C,PRPH,PTCH1,SH3BGR,SH3GL3,ASAP3,WDR47,FAM214B,SMARCD3,TNIK,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,REEP1,ITM2C" Drug 2462_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.84E-09 2.37E-04 4.24E-07 4.82E-06 59 177 "ABAT,OSBPL1A,AK2,C1QTNF3,GAS7,EIF4G3,N4BP2L1,CFLAR,TPP1,FADS2,CPS1,FEZ1,ARHGEF10,IPCEF1,CX3CR1,HDAC4,SIRPA,ZNF804A,ANKRD46,FRY,KMT5B,SH3YL1,CAP2,CAMKK2,GART,GLS,IRAK3,ZNF862,NEK1,OGDH,P2RX7,PDE3B,RETREG1,SLC25A23,PPP2R5C,PPP3CB,PIGG,PTPRE,RAD51D,RBBP6,RPRD1A,RPS6KA2,TMEM156,DGLUCY,ASRGL1,SH3BP2,DOCK10,CEP68,GSE1,FAM208A,KIAA0930,TCF7,CBX5,TNS1,FLRT2,NSD2,TRIM9,NAV3,MPPE1" Drug CID000000191 arabinosyladenine Stitch 5.04E-09 2.47E-04 4.40E-07 5.01E-06 180 762 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,NME5,AK2,AMPD2,AMPD3,APC,NT5C3B,MADD,PDE8B,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,GPC2,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALM1,CAPN3,CARS,CBS,CCK,P2RX6,CD38,ENTPD2,LRBA,CACNA2D2,CHRM1,MYL6B,ABCG2,AKAP6,COL4A5,COL11A2,GAL3ST1,GDA,BOC,EARS2,DBI,AK5,SLC29A4,DPP6,DRD1,FARSB,ABCC9,EDN1,LPAR6,F3,F5,F8,FCGRT,PPP1R1B,ACTL6B,PRKAG2,AK8,ATP2C1,AHCYL1,GART,GCK,SESN1,GNAS,GPD1,GPD2,GPM6A,LPAR4,GRIA2,GRIA4,GRIK1,GRIK2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GUCY1A2,GUCY1A1,GUCY1B1,TNFAIP8L3,ATCAY,ICA1,IDH3A,IDH3B,IL12A,KCNB1,KCNJ3,KCNJ5,KLHL23,KCNMA1,MAT2A,MYBPC1,MYH3,MYH6,MYL3,P2RY13,NF1,NPY,NPPA,NPR2,OPRL1,P2RX7,P2RY1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PKM,POLR2F,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,NDUFS7,PYGM,GAL3ST4,RNASE1,RNASEL,RNH1,ZC3H14,ADAL,RYR1,RYR3,MAPK12,SARS,FNDC3A,SLC6A7,SLCO1A2,TET1,DDN,SST,ABCC8,TAC1,TAC3,ATP11A,AHCYL2,TK2,ACTR6,PIK3R5,RBFOX2,METTL3,UBTF,P2RY12,PLPPR5,GAL3ST3,PLD4" Drug 5308_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.12E-09 2.51E-04 4.47E-07 5.08E-06 58 173 "ADD3,NME5,MARK4,CAPRIN2,BMP7,ST3GAL5,SCAPER,RAB29,BAIAP3,CLGN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,TSPAN5,EFNA3,EFNB3,STX2,DPYSL4,FYN,CYP46A1,RAB40B,STON1,KIF5C,MPP2,MXI1,NAP1L3,NEK1,SERPINE2,SERPINI1,PIK3CD,PRPH,PTCH1,RAB3A,SH3GL3,SYBU,WDR47,PKNOX2,ZCCHC24,KIF21B,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,GDPD5,SLC17A7" Drug CID002733618 Frie Mao 1-43 Stitch 5.35E-09 2.62E-04 4.61E-07 5.24E-06 29 61 "AMPH,BSN,RHBDL1,CLTC,SNAP91,DLG4,STX2,ADGRV1,GRIK1,GRM1,GRM2,GRM5,GRM8,CIT,MAP4,MYO5A,MYO7A,P2RX7,SNTG1,EPN1,PRPH,SNAP25,STX1A,SYN2,SYP,SYT1,TRPC1,SLC17A7,NUP214" Drug 4435_UP retinoic acid; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADRA1D,AGT,NR0B1,BEGAIN,ANK1,GAS7,CDC14B,PDE8B,ASPA,N4BP2L1,KIF1A,GYG2,CACNG1,KALRN,CAMK2B,CDO1,PICK1,CSF1R,PLCH2,C2CD2L,SMG7,SPOCK3,CHRDL1,TRAPPC9,ABCC9,SRPK3,EN2,ZNF391,APC2,REEP2,DCTN2,GATM,SRCAP,GLI2,GPM6B,GPR17,GRIN1,HTR2A,KCNJ4,VWA5A,MOBP,NPY,OMG,GPR85,PURG,PPP5C,PTCH1,PTPRN,PTPRN2,RGS12,MYH14,NEK11,SH3BP2,DOCK10,FAM214B,SLC15A2,RBM34,KLHL4,CHST5,TRIO,TMPRSS5,SLC17A7,KAT6A,GAN" Drug 6459_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ABHD6,NDRG2,ADORA1,BIN1,PPFIA3,AQP4,ATP1A2,ATP2B2,ALDH7A1,BCL2L2,GYG2,LDLRAD4,DLGAP1,ADGRG1,CLCN4,TPP1,STOML1,ARHGEF6,WHRN,COL9A3,AATK,PLCH2,PDE4DIP,CNTNAP2,DCAF4,SPOCK2,DCC,EIF5,ELAVL3,EFS,ATP8A1,C1orf61,AGAP2,SIGLEC8,INPP5K,PCDH17,GUCY1A2,HAS2,HLF,ICA1,IFI16,ITIH2,KCNJ5,KCNMA1,MBD1,MID1,CNOT4,OPCML,PRKAR1B,ELOVL2,RALGDS,RGR,RPS6KA2,S100B,PPP4R3A,PDZD2,IZUMO4,WSCD1,THBS4,TLR4,LAT2,NSD2,ZNF711,PHTF2" Drug 3997_UP Cefotetan [69712-56-7]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADD2,ADRA1D,SPARCL1,CDC42BPA,PPP4R4,PTCH2,CFLAR,SYNJ1,FUBP1,CAMK2B,CD86,CBFA2T2,NEURL1,PLEKHB1,TPP1,LY86,AKAP6,AKAP5,PLCH2,ERC2,RIMS2,DCAF4,EDRF1,TOX,DTNB,DYRK1A,EFNB3,NRN1,ATP8A1,KIAA1109,OLFM1,PRELID3A,DKK3,GPR17,GRM3,ELOVL5,IRF8,IL6ST,ITGA7,MMP16,P2RY13,SLCO1C1,TREM2,PDE2A,NLE1,PPP2R2B,ELOVL2,PTPRN2,BEND5,GAL3ST4,MRAS,SLC1A6,PLCB1,ASTN2,MCF2L,PCDHA5,VIPR2,LAT2,WNK1,MAP3K12,SLC17A7,KCNAB1,PHTF2,DPF3" Drug 2739_UP Iopromide [73334-07-3]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "TTYH1,TRMT9B,CADM3,AZGP1,ADGRB1,KSR1,CACNB4,MAP7,DGKI,CDH2,LARGE1,DLGAP1,DNAJB5,CABP1,NCOR2,PDE4DIP,CTNND2,INTS1,PHYHIP,BRINP1,MFAP3L,HEYL,MBNL2,AASS,FAM198B,TBC1D16,FGFR3,ZNF44,GAD1,GPM6B,GRK4,HPCA,KCND3,MAPT,MBNL1,MID1,AFDN,ADAM22,NTRK2,SEPT4,PPP1R1A,KHDRBS2,SUGCT,SCN2B,SCN8A,MRAS,NLGN1,ZNF415,SOX2,HECW1,SSTR2,PCDHGB6,DOCK9,PHF24,TRIO,AMACR,LMF1,KLC2,XRCC4,SLC26A10,SPHK2,EVI5,SEMA3B,TIGD6" Drug 3512_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADORA1,SEMA7A,FAM131A,CFLAR,BTK,CFAP410,CACNA1D,RUNX1T1,P2RX6,CDC42,EPS15L1,FAM149A,ENTPD4,AATK,CSF1R,GREB1,CDON,DRD1,ATN1,MTSS1L,ZNF589,FGF13,SEMA6C,AFF2,SEPT9,LYVE1,GLYR1,GNG4,GPM6B,GPR22,PCLO,GRM8,AP4S1,KCNJ4,MARK1,AFDN,NEUROD1,OPRL1,ENPP2,PLCD1,STRN3,LRP12,PPP2R2B,PPP5C,RAB3A,RGS12,RASA3,DOCK10,ST6GAL1,LIMS2,SNCA,TSNAXIP1,SPTB,CDK19,MAPK8IP3,ATP11A,KIAA1107,WSCD1,PCDHGA10,THBS4,TRPC3,FLRT2,ZFP37,ZIC3" Drug 4691_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ACTN2,AMPD3,ANK1,GAS7,SLC4A4,ATP2A2,CFLAR,GYG2,CA4,CAMK2G,KRIT1,USP2,SEPT7,QKI,HOMER3,CNTN1,CHD1L,CRMP1,RGS6,FAM169A,RIMS3,ARMCX2,SPOCK3,EXOG,RASGRP2,FGF12,FOXG1,SRCAP,RAB30,PCLO,GRM8,INPP1,KCNJ3,KIT,MAP2,ADAM11,KITLG,MMP16,MYT1,OPCML,PDE4B,PDPK1,SERPINI1,SLC25A23,STRN3,PPP5C,MAPK7,ELOVL2,TTLL7,GSTCD,ROM1,KCNIP1,RASA3,FBXO11,SLC1A7,CCDC88A,SLC11A1,LIMCH1,RBM34,CLSTN2,PHLDB1,POPDC3,RUNDC3B,WNK1" Drug 5505_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ABR,ABHD6,ACTN2,ADD2,TRMT9B,ADGRB1,CACNA1I,CALB1,INA,NEURL1,ASIC3,CLTB,FADS2,AKAP7,CPS1,LRIG1,NOS1AP,GPRASP1,GSDME,SLC12A6,HEYL,PLXNC1,MTSS1L,CDKL3,PIPOX,NRN1,FHL1,ZNF44,HBS1L,LYVE1,GPM6A,GRIK5,GRM2,WIF1,KIF5A,LIG4,MAOB,MAP2,MEF2C,MID1,NCAM1,NF1,NPPA,P2RX7,MTRF1L,LRRN3,MAPK10,RELN,NEK11,PAQR6,KCNIP2,FRMPD1,SYBU,RPH3A,PKNOX2,SHANK2,PDZD2,SPP1,TBCEL,WSCD1,CABIN1,AMOT,ZNF24,ITM2C" Drug 6489_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADD2,MRTFA,APC,GAS7,BRINP2,CCDC181,CADM3,CAMK2G,CHRNA4,TAOK2,HOMER3,PCYT1B,COL9A3,ABI3BP,CSF1,GREB1,TBC1D5,SPOCK2,MFAP3L,EFNA3,EGR3,RASL12,KIAA1109,OLFM1,FGFR1,CAMSAP1,FHL1,DCTN2,EFCAB2,SRCAP,RND1,GPD2,GPER1,GRK4,GRM8,JAK2,KCNF1,VWA5A,MAN2A2,ADAM22,SERPINE2,MTRF1L,RELN,ELOVL2,ATG16L1,GTDC1,SBF1,ASIC4,SGK1,FRMPD1,FNDC3A,SYBU,SLC11A1,MYT1L,ZNF423,ST5,DMXL2,HEY2,TMOD1,TNS1,ZKSCAN5,VGF,WIPF1,SMIM8" Drug 5529_UP Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADCY6,AK2,PLA2G4C,PDE8B,ATP2B2,ATP6V0A1,NRP2,GYG2,CACNA1I,B4GALT6,AKAP7,ATRNL1,EDRF1,DCAF8,MAGI2,TMCC2,SLC12A6,DSCAM,HIPK3,MBNL2,C1orf61,ANKFY1,GABRA4,ADAM28,POLL,GRB10,ADAMTS13,GRM7,GUCY1A2,ATXN2L,KCND3,MAN2A2,MOBP,NF1,KCNK10,SNTG1,PDE4B,GPR85,SLC25A23,LRP12,PRODH,MASP1,GDPD2,ELOVL2,RIPOR1,TMEM231,ATG16L1,C1orf54,ZDHHC14,SH3GL3,FAM214B,SLC11A1,PDZD2,WDTC1,KDM4C,SPTAN1,RBM26,MAPK8IP3,CEP68,STX1A,KIAA1107,DOCK9,ZMYND8,LMF1" Drug 4501_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "DPF1,ADCY2,SLC12A5,PLA2G6,C1QTNF3,ALK,BEGAIN,AMPD3,APAF1,BCAS1,N4BP2L1,NEURL1,CDH8,CDO1,SLC24A2,STOML1,CSF1,SUSD5,PPP6R2,SEC14L5,MAGI2,RABGAP1L,ECM2,ST8SIA3,NCALD,ETV1,C1orf61,TBR1,GABRB3,GAP43,GNG3,SCIN,KCNN1,MAN2A2,KITLG,AFDN,NOVA2,PDE4B,GDPD2,ZSCAN32,PTPRN2,ZSCAN2,ZMAT4,MYH14,CARF,EMID1,RYR1,TRIM46,SLC1A7,SLC2A5,KANSL3,PKNOX2,HECW1,RBM26,LHPP,SEMA4A,KLHL4,PCDHGA10,AP4E1,TNS1,VAV2,LAT2,KCNAB1,MVB12B" Drug 2285_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "TRMT9B,AMH,CDC42BPA,APLP1,MARK4,BRINP2,SLC4A4,ATP2B2,N4BP2L1,NRP2,SCAPER,HIP1R,USP2,KCNAB3,AKAP6,WHRN,CSF1R,VCAN,NOS1AP,ARHGAP24,BRINP1,ATN1,MTSS1L,FOLR2,EFCAB2,FAM49B,OGA,GPR162,GPR75,ATF7,GRM8,GSTM5,KCNC1,KCNMA1,KIFC3,KIT,NDUFA5,NF1,NPPA,OMG,SNTG1,PFKFB2,MAPK8,PTAFR,CRTAC1,TCP11L1,SEMA6D,STUM,SLC2A5,SOX10,ATP10B,MAPK8IP3,JMJD6,ARC,EXOC7,TCF7,PHF24,RALYL,PSD3,TEX15,SEZ6L,TRO,FLRT2,VAV2" Drug 5515_UP Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "DPF1,C1QTNF1,AMH,APBA2,CDC14B,CDK10,SEMA4G,CHRD,ADAM23,SYNJ1,GYG2,CACNB4,CLCN4,CNTFR,WHRN,SIPA1L1,VCAN,CNTNAP2,EDRF1,RIMS3,ARMCX2,SLC12A6,DRD1,ECM2,EDNRB,SIDT2,EFNB3,NRN1,FER,AFF2,EFCAB2,ERGIC3,FYB1,NR3C1,SOX21,KCNC1,KCND3,KCNH2,KCNN1,IPO5,MN1,TAGLN3,ZNF862,CLDN11,PAX6,PDE3B,POLG,PPARA,RELN,ZSCAN32,ATG16L1,RASGRF1,ZDHHC14,SALL1,SH3GL3,CCDC88A,PDZD2,SOX11,HECW1,ARHGAP26,ATP10B,DOCK9,PLPPR2,XRCC4" Drug 4259_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ARID1A,AGT,AQP4,ASCL1,CCDC181,ATP1A2,N4BP2L1,NOL4,CACNA1I,CACNA1G,NGB,NRXN1,FAM149A,CABP1,NRG2,HAPLN1,NCOR2,CSF1,CX3CR1,NOS1AP,DCC,HS3ST2,ABCC9,SRPK3,RASGRP2,F5,AFF2,CSDC2,GNAL,GRIK3,GRM1,PTGDR2,HTR2A,HTR5A,ICA1,KCNH1,PACRG,MBNL1,ADAM11,MGAT3,NF1,NTRK3,OGG1,P2RX7,SUSD4,KHDRBS2,ZMAT4,RGR,SCN2B,SLC1A6,SLCO1A2,SNAP25,SOX15,NFASC,ATP10B,INKA2,SYP,SYT5,TRIM2,DOCK9,THRA,TRH,CAMK1G,GAN" Drug 3552_UP Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ARID1A,ADORA2A,PLA2G6,LTBP4,BIN1,APBA2,KCNAB2,APC,SEMA4G,DDX3Y,CA4,NEURL1,ASIC3,CHN2,TPP1,AATK,CSF1R,ATRNL1,CNTNAP2,GREB1,RIMS2,RIMS3,DGKG,DLG4,EFNB3,EN2,PTK2B,FLNC,AFF2,GAD2,ERAP1,DISC1,GNAO1,ADAMTS13,ELOVL5,KCNH2,KCNN1,KCNQ3,VWA5A,MDFI,MEF2C,MX1,MYO7A,NF1,OPCML,KCNK10,PC,PDE1C,TRHDE,PTN,RGS12,TCP11L1,ABLIM3,PDZD2,ZC3H13,SPTAN1,PLCB1,ROBO3,TBCEL,HEY1,TRPC1,TUBB1,SPHK2,SEMA3B" Drug 7226_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "APBA2,AQP4,ARRB1,ASTN1,ATP1A2,CADM3,FUBP1,SOCS6,ZFYVE9,ARMC8,SDC3,ARHGEF4,EDN1,EFNA3,MBNL2,RASGRP2,EZH1,FAM198B,FGFR3,ALDH1L1,GFER,GLYR1,POLL,GNAO1,GNAS,GNG3,PRUNE2,LILRA2,STON1,GRIK5,PTGDR2,HLF,LMO1,MDFI,KITLG,AFF1,MSI1,P2RY1,PAH,PHKG1,NLE1,PPARA,RELN,BEND5,MRAS,CNKSR2,SLN,CXXC4,SOX2,MLC1,SYN2,WSCD1,RPGRIP1L,PCDHA6,DAAM2,TNS1,TRIO,ZKSCAN5,TUBB1,FAM155A,UBE3A,GDPD5,RNF170,SSPN" Drug 3230_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "SPARCL1,ALCAM,GAS7,DNAH17,ASPH,ATP2A2,ALDH7A1,GYG2,BAIAP3,LDLRAD4,CFAP410,CA4,CACNA1A,SLC16A4,NEURL1,PLAA,CNTNAP2,PHF14,ARHGEF4,NTM,EFNB3,CDKL3,F3,FGF12,IQCG,NEU3,ALDH1L1,GPM6B,GRIK2,SHISAL1,KCNMA1,KCNN1,LSS,MARK1,CNOT4,SNTG1,PLCD1,EPN1,PPARA,PPP5C,PRKCB,MAPK4,MAPK7,PLPPR1,SCN2B,SLC2A5,ARHGEF40,ZNF334,SLC14A1,ZNF415,ARHGAP26,CDK19,PSD3,PCDHA5,TMOD1,DAAM2,TPM2,RUNDC3B,TRO,TRPC1,VAV2,GDPD5,KCNAB1,PHTF2" Drug 6618_UP Protoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ABAT,ARID1A,ADORA1,C1QTNF3,GAS7,SYNJ1,HAP1,CBS,CRLF1,FOXN3,CHRNB2,CLCN4,RCHY1,PLPPR4,SPOCK3,DTNA,EGFR,ING4,ELAVL3,APC2,ETV1,DLC1,KIAA1109,FGF1,FGF12,FGFR1,FLT1,DCTN2,GAD2,ALDH1L1,GPM6A,GSN,GSTM5,ATXN2L,ICA1,SCIN,MEF2C,AFDN,PALM,PDGFRA,ENPP2,PGAM2,PROX1,PRPH,VPS13C,ZSCAN2,C1orf54,RGS4,SUPT20H,ASAP3,PEX26,KIF21B,PHLDB1,TACR1,TAL1,CDK20,RUNDC3B,VGF,LAT2,ZNF24,ZNF74,KCNAB1,EPM2A,NLRP3" Drug 5448_UP Iopanoic acid [96-83-3]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "PLA2G6,ADGRF5,SEMA6A,CNTNAP1,CDC14B,PPP4R4,DDX3Y,SLC4A4,N4BP2L1,SYNJ2,SLC16A4,ADGRG1,CPS1,ATRNL1,GREB1,JAKMIP2,MAGI2,SHANK1,DTNA,EDNRA,EGFR,ING4,TNK2,EPHB1,ZNF589,AGAP2,ERAP1,SIGLEC8,GLS,NR3C1,NXPH3,ICA1,TJAP1,KCNJ3,KCNQ3,KIT,MAP4,MAPT,MGAT3,MID1,PALM,PENK,PLP1,TNPO2,RELN,ZSCAN2,RAD52,ZMAT4,RFX2,RGS4,ZFHX4,RPS6KA2,SH3GL3,ARHGEF40,KDM4B,ZCCHC24,DOK5,CDK19,R3HDM1,TRPM2,ZIC3,SLC30A3,PLSCR4,SSPN" Drug 4400_UP Prednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "APP,SEMA4G,AZGP1,BCL2L2,GYG2,BAIAP3,RUNX1T1,SEPT7,KCNAB3,ASIC3,CNTNAP2,DCAF4,CNIH3,SPOCK3,EDN1,FRY,EFNB3,FAM13A,ELAVL2,LRRC17,CEND1,OLFM1,FGFR1,NEU3,GLRB,GLS,STON1,GRIK1,GRM7,GSTM5,SOX21,LAMA2,LMO1,MID1,ADAM22,MX1,NNAT,NPR2,PDE1C,PIK3CD,PLCD1,PNMA3,CDIP1,TNPO2,LRRN3,CEP41,GDPD2,CRTAC1,RPS6KA2,ZFP2,STUM,CPEB3,SNAP25,CAND2,HECW1,ARHGAP26,CDK19,AJAP1,HEY2,TNS1,CA14,VAV2,ITM2C,GJC2" Drug 6634_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "GAS7,DDO,ASTN1,AZGP1,SYNJ1,SYNGR3,NRXN3,CLCN4,ENTPD4,CNTNAP2,DGKB,DCC,C2CD2L,SMG7,ATN1,EDIL3,HIPK3,ZNF391,PIPOX,FGF1,FGFR1,FOXG1,FLT1,CYP46A1,RUNDC3A,GNAL,GRM7,GRM8,PTGDR2,HRH3,ATXN2L,IGFBP1,ITIH2,VWA5A,KITLG,MMP16,MOBP,CD200,NOVA2,NTRK2,PCDH9,GPR85,PPP1R1A,PRKAR1B,PROX1,PRPH,MASP1,ZSCAN2,GAL3ST4,IL17RB,FRMPD1,ASAP3,CXXC4,OGDHL,SNCA,TNIK,BEX1,COBL,SEZ6L,TPM1,TPM3,TRIO,NT5M,MVB12B" Drug 5085_UP Iodipamide [606-17-7]; Up 200; 3.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "APBB1,CDK13,RASL11B,ATP6V0A1,ST3GAL5,BAIAP3,RUNX1T1,NEURL1,ARHGAP22,CLCN4,CNTN1,AKAP5,MYRIP,CRY2,FAM131B,SEMA3D,EFNB3,MRNIP,COQ7,CEND1,FGF1,DCTN2,SORBS1,FYB1,GAA,ZNF44,DENND2A,SIGLEC8,ATP8A2,GRK4,GRIK2,SPACA9,SYNPO,ITGA7,ADAM22,MX1,NF1,NOVA1,NTRK2,PFKFB4,PRPH,PTCH1,PTPRH,PTPRN2,RIPOR1,TMEM231,RGS10,RPS6KA2,RPS20,ZNF821,SLA,BTBD7,SNCA,KDM4B,MAPK8IP3,DOCK9,ARHGEF12,ZNF34,TRPC1,TRPC3,VIPR2,LAT2,SPHK2,NUP214" Drug 3813_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ADRA1D,AMPD3,CDC42BPA,GAS7,APOC1,ALDH7A1,MYRF,IL33,CFAP410,CDC42,LARGE1,TPP1,HOMER3,IFFO1,TCEAL2,CNTNAP2,MFAP3L,DTNA,HIPK3,DMTN,EPHA5,ETV1,SCML2,FGF1,FYB1,C1QL1,GNAS,GNG3,GRIK5,MUM1,ATXN2L,ICA1,TJAP1,ITIH2,KCNB1,KCNMA1,MAP2,MARK1,ADAM22,TAGLN3,OPRL1,PDE4A,MINDY2,PRKAR1B,MAPK8,TMEM206,RPS6KA2,ZFP30,NTNG1,RPH3A,PREX2,ZNF334,BTBD7,SNCA,MAPK8IP3,KAZN,SMG6,PSD3,CHST8,AP4E1,FLRT2,LMF1,KCNAB1,MVB12B" Drug 3580_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "ASIC1,KCNAB2,APOC1,CHRD,ATP1A3,KSR1,SYNJ2,SCAPER,ARHGEF1,CRLF1,CHN2,HOMER3,CNTFR,COL9A3,RCHY1,TENM4,CHD5,CNTNAP2,RIMS3,SMG7,RCAN1,EFNA3,LRRC23,KAT8,AGAP2,FYN,TMEM8B,GPR75,GPER1,ADAMTS13,TJAP1,KCNB1,KCNN1,SMAD1,MGAT3,AFDN,BCO1,NEUROD1,NF1,NOVA2,OPRL1,PALM,MBOAT7,POLG,MINDY2,PRODH,RELN,SAMD9,ELOVL2,FAM120C,ZNF493,RGS12,TTLL7,SLC9A5,OGDHL,KDM4B,CDK19,SZT2,SYNE1,SLC44A1,TUBB1,CLIP2,GDPD5,SSPN" Drug 5081_UP Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "NDRG2,SLC12A5,ADRA1D,AMPD3,AQP4,ATP1A3,ATP2B2,MYOM1,BMP7,CACNA2D2,GPR37L1,CHRNA4,WHRN,ABCG1,RGS6,VCAN,BRINP1,ATN1,DTNA,ST8SIA3,EDN3,EIF4G2,ANKMY1,SYT17,GFER,LYVE1,GLI2,TOX3,GNG4,HNMT,ICA1,KCND3,PACRG,MAP2,ADAM11,MOBP,NEUROD1,NOVA1,OPCML,PALM,PDE4B,MAPK10,PTPRB,RASGRF1,RGS4,KCTD17,KCNIP2,SH3BP2,BCAN,FAIM2,KDM4C,DDN,ATP10B,VAMP1,KAZN,TAL1,SMG6,DNAH7,SEZ6L,VGF,MKRN3,SLC17A7,FAM13C,CAMK1G" Drug 5534_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.53E-09 2.71E-04 4.61E-07 5.24E-06 64 199 "RALGAPA1,ACTN2,ADRA1D,OGT,APC,GAS7,AQP6,CDC14B,PLA2G4C,AZGP1,SCAPER,MTMR3,CACNA1G,CFAP410,CA4,CACNA1D,CALB1,NEURL1,CDH18,CHI3L2,CRYM,CSF1,LRIG1,SIPA1L1,DCT,SLC12A6,ATN1,PLXNC1,ZNF589,FHL1,SCARA3,B3GAT1,GAB1,HBS1L,GATM,TOX3,GPER1,NR3C1,BTN2A1,HNMT,DHX35,MAN2A2,NF1,PC,STRN3,LRP12,MBOAT7,MAPK7,PTAFR,ELOVL2,RASGRF1,GTDC1,STUM,SCG5,SH3BP2,PKNOX2,KIF21B,SOX15,STX1A,SMG6,OBSL1,CABIN1,TRO,ZKSCAN5" Drug ctd:C030935 benz(a)anthracene CTD 5.72E-09 2.80E-04 4.76E-07 5.41E-06 274 1264 "CLK4,ABHD6,ADD3,ERMN,ADORA1,ADRA1B,PLA2G6,SPOP,ARHGAP20,FAM135A,OGT,ANK3,LCORL,CPNE5,AQP4,CDC14B,PPP4R4,ARNTL,ASGR1,ASPH,ATP2A2,RGS11,RGS9,BMP7,DST,CACNA1I,C5,MMD2,THSD7A,CAMK2G,KYAT1,USP2,CIART,SRSF11,CHRNA4,MAP4K4,AKAP7,ABI3BP,IFFO1,TOGARAM2,CLOCK,RBM39,CRY2,AATK,CSF2RA,OSBPL3,RASGEF1C,PITPNM3,GREB1,DCAF4,MYADM,FGFR1OP2,TCAF1,RIPOR2,PHF19,DCC,ELMSAN1,MTX3,NR1D2,FAM57B,ARRDC4,ABCC5,ABCC9,AASDH,EDN1,EDNRB,SYT15,KLHL5,PHF20L1,EGFR,KMT5B,SRPK3,BSCL2,EML1,EPB41,ERBB2,IGSF6,CEP85L,REEP2,FAM198B,ZMYND10,POLR1B,POLK,ZMYND15,FOLR2,PDLIM5,TPK1,NSG2,STAU2,PNMA2,DOT1L,OGA,GABBR1,GALNT15,INPP5K,CPLX2,ALDH1L1,FREM1,PCDH17,PPARGC1A,MALT1,LYVE1,GJB1,SPIN1,AIFM3,HTATSF1,PSRC1,GPD1,CCDC184,PCLO,CNTRL,GRB10,DIDO1,PLCD4,SERP2,NR3C1,PTPN5,TMEM25,MFSD2A,PSIP1,FAM107A,SLC2A6,NXPH3,KLF12,BACH2,HLF,HMGB1,HNMT,CPT1C,DHX35,CELF5,ICA1,IFI16,ITGA7,KIT,PAXBP1,MAT2A,EFHB,MDM4,SHC3,KITLG,CD200,BLOC1S2,ADAM22,MSR1,NRBP2,THYN1,DDX25,NRCAM,SETD4,P2RX7,ZDHHC22,PAH,PAK3,PBX1,PDE4A,PFKFB2,PFKFB3,ZFYVE21,ANKRD16,PMP22,LRP12,PSAT1,PILRA,PPARA,TATDN3,PRKCB,MAPK10,SLC26A11,GRAMD1C,DIRAS2,PRODH,LAMA1,GON4L,MTMR10,PTN,PTPRB,PTPRG,TUG1,MARCH1,PID1,IQSEC3,RAP1GAP,ARID4A,RBBP6,MORC4,RGS3,RGS12,CCDC82,PRR5L,MEG3,HUNK,NCBP3,SCN4B,SELL,ITSN1,FAM102A,SHC4,HKDC1,MAGI3,DZIP1,ZNF365,RUFY2,SLC8A1,ARHGEF40,SLC15A2,ZKSCAN3,PALLD,SCN3B,SPATA7,KIF21B,GLT8D1,IZUMO4,SPTAN1,RBM26,TAB2,CLSTN2,MESP1,INKA2,MAPK8IP3,SEPT3,NECAB1,SYNE2,PLCB1,COBL,ATP11A,ANKRD12,KAZN,IQCE,VWA3A,EHBP1,TCF7L2,TRIM2,TCF12,SZT2,PCDHGA9,SYNE1,NSD1,PCDHAC2,GPRIN3,SLC35G2,AHCYL2,DNAH7,CHST8,ZMAT3,RASD2,ZNF346,TRPC3,ZMYND8,CA14,LRTM2,TUBB2A,TMEFF2,RPRM,PDIA2,MICAL1,CLDND1,ATP6V0E2,SLC26A10,CRB2,ZBTB38,ZBTB16,REEP1,ZSCAN26,STOX2,SIGLEC10,RGS7BP,DNAH10,FAM13C,GJC2,TTC7A,SSPN,AAAS,CPNE4" Drug DB00142 L-Glutamic Acid Drug Bank 5.74E-09 2.81E-04 4.77E-07 5.42E-06 31 68 "ABAT,EARS2,GRIN3A,SLC25A18,AASS,FOLH1,GAD1,GAD2,GLS,GLUL,GPT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM7,GRM8,PSAT1,SLC1A2,SLC1A3,SLC1A6,SLC1A7" Drug 6626_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ARID1A,ADD1,ADORA3,ADRA1D,C1QTNF1,ALK,EPB41L5,GAS7,ALDH7A1,CFLAR,BAIAP3,RUNX1T1,ARHGAP33,AKAP5,RCHY1,EDRF1,SPOCK2,DTNA,DTNB,EDN1,HIPK3,EGFR,VPS13B,ZNF391,ETV1,DLC1,KIAA1109,FGF1,PRELID3A,ATP8A2,RUNDC3A,GPD2,GSN,KLF12,ELOVL5,ICA1,IL6ST,KIT,MAP4,KITLG,CTNNA3,NEUROD2,PCDH9,PFKFB2,PRPH,ZSCAN2,RALGDS,C1orf54,KCTD17,PNMA8A,SCN8A,SUPT20H,ASAP3,SLC11A1,SLCO1A2,DOK5,MAPK8IP3,PHLDB1,CRTC1,TEX15,CHST5,LAT2,DPF3" Drug 5468_UP Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "NR0B1,BIN1,APC,CDC14B,ALDH7A1,N4BP2L1,CFLAR,USP2,RCBTB2,FOXN3,TAOK2,HAPLN1,DCAF4,HDAC9,GPRASP1,SPOCK2,GIT2,HP1BP3,ST8SIA3,EN2,STX2,F5,KAT8,FER,FGFR1,ERAP1,COPS8,NXPH3,C2orf72,INPP5B,KCNJ5,MMP16,GIT1,NCAM1,NDP,NEK1,NELL2,NNAT,NOVA2,PDE1C,PENK,SERPINE2,PRKAR1B,RPS6KA2,RYR1,ABLIM3,ELMO2,LIMCH1,HECW1,ZC3H13,LHPP,TROVE2,WSCD1,DICER1,DAAM2,CHST5,TRIO,AMACR,ZMYND8,LMF1,ZFP37,ADAMTS9,FAM13C" Drug 3969_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ACTN2,ARID1A,BIN1,APAF1,APOC1,FUBP1,CACNA2D1,CDH18,DLGAP2,GPR37L1,CRMP1,NOS1AP,GSDME,DYRK1A,ING4,ERBB4,ETV1,ANKMY1,KIAA1109,CAMKK2,ALDH1L1,GDF9,POLL,GNAO1,GPER1,PCLO,GRIA4,GRIN1,GRM7,SHISAL1,JAK2,LIFR,KITLG,AFDN,MMP16,MPP2,NTRK2,TREM2,EPN1,PLP1,PNMA3,C19orf57,POU3F4,CEP41,GRAMD1C,ZSCAN2,RPS20,SYNDIG1,KCNIP1,CLIP1,ASAP3,SLC2A5,PKNOX2,SHANK2,PDZD2,SOX10,TAC3,ATP11A,SEMA4A,DOCK9,SEZ6L,CHST5,FLRT2" Drug 6172_UP 17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "SYN3,ALK,SYT13,BIN1,ARSE,SLC4A4,THSD7A,HIP1R,CBFA2T2,COL4A5,FAM169A,SNPH,ARHGAP24,DGKG,SPOCK2,MFAP3L,SV2B,HS3ST2,DSCAM,FAM13A,MBNL2,PLXNC1,MRNIP,VPS13B,REEP2,CAP2,AFF2,GABRG2,SEPT9,PCSK1N,GRIA4,HPSE2,MYO6,P2RY13,SLCO1C1,NOS1,OPRL1,CLDN11,KCNK10,PDE4A,MASP1,LRRC49,PTPRD,PTPRN2,KCTD17,HSPA4L,PPM1E,SLC11A1,SHANK2,SORCS3,CLSTN2,ASTN2,DMXL2,TRIM2,HIF3A,TPM3,TRPC1,ZMYND8,UBE3A,LMF1,SLC13A3,SLC26A10,PLSCR4" Drug 4624_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ADD2,LTBP4,CDC42BPA,SEMA7A,KSR1,GYG2,CACNA1G,CA4,MAP7,EPS15L1,TPP1,WHRN,AATK,VCAN,NOS1AP,C2CD2L,EDNRA,SIDT2,EFNA3,EBI3,OLIG2,DLC1,KAT8,AGAP2,GABRA2,CSDC2,RUNDC3A,GNG4,PRUNE2,GPM6B,RAPGEF4,GRIN1,GRM8,IRAK3,HPSE2,JAK2,KCNC1,PACRG,ADAM11,MMP16,MYO7A,CNOT4,NTRK3,SPATA6,FA2H,SNRK,MARCH1,SEMA6D,ZFP2,SELL,SLC1A6,RIMS1,SNCA,SP2,BEX1,ATP10B,PHLDB1,TACR1,PCDHGA1,PHF24,TMOD1,VGF,ZIC3" Drug 6999_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ASPHD1,ABHD6,NDRG3,MRTFA,NCOA1,BMP7,SCAPER,GYG2,BRSK2,SYNGR3,LHX2,NECTIN3,CRY2,ABCG1,ARHGEF10,DBN1,SGSM2,SEZ6L2,SIDT2,EFNA3,MBNL2,EGR3,ENO2,RASGRP2,FECH,KIAA1109,FHL1,DPYSL4,GAD1,POLL,GNG3,GRM7,RASSF8,ITPKB,MAP4,MAPT,MBD1,MGAT3,MPP2,NRGN,NUMA1,PIK3CD,RETREG1,MTRF1L,FA2H,PRPH,PTCH1,FBXW7,EMID1,ZNF821,FRMPD1,ARHGAP26,MAPK8IP3,ELOVL4,STXBP1,COBL,MTCL1,MCF2L,TMEM121,TIAM1,TPM1,PRMT8,PLPPR2" Drug 4373_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ASPHD1,ALK,MRTFA,BIN1,APP,PDE8B,ATP2A2,MTMR3,GYG2,CACNA1I,CBFA2T2,CDC42,CNTFR,AATK,PHF14,MFAP3L,DRD1,EDNRA,HIPK3,EFNA3,EFNB3,PLXNC1,ING4,TNK2,RASGRP2,OLFM1,FGFR1,SCARA3,AGAP2,ANKFY1,RND1,GLS,GNG4,KHK,MAP2,MID1,GIT1,BCO1,NF1,NPTX1,SERPINE2,PLXNB1,POU3F2,PTAFR,ELOVL2,ATG16L1,FAM184A,TCP11L1,BCAN,DOP1A,TSNAXIP1,SPTAN1,JMJD6,WSCD1,PSD3,PCDHA6,GPR161,TMOD1,DAAM2,TRIO,VAV2,ITM2C,NUP214" Drug 3212_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ABHD6,ARID1A,NDRG2,ANK1,APP,PRX,ATP1A3,SLC2A11,ALDH7A1,BTRC,CACNA1D,CAMK2G,KIAA1549L,BAG4,NRG2,CHD5,PDE4DIP,ARHGEF4,NOS1AP,RIMS3,ARMCX2,DTNB,DYRK1A,EDNRB,EFNA3,EFNB3,PLXNC1,SRPK3,ERCC2,CDKL3,KIAA1109,AFF2,PRELID3A,FYB1,GPER1,GSN,GUCY1A2,KCNK1,KCNN1,MBNL1,ADAM22,TAGLN3,NEFH,NF1,NPR2,NTRK2,CDK18,TCP11L1,RPS6KA2,ASAP3,SLC2A5,PKNOX2,CXXC4,EMC1,SS18,ACSBG1,POPDC3,SMG6,WSCD1,TRIM2,DOCK9,PHTF2,RNF146" Drug 4180_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ABHD6,ADCY6,KIDINS220,LTBP4,SEMA7A,APBA2,GAS7,MARK4,SLC16A4,CDH8,CDH18,CACNA2D2,CLTB,FADS2,WHRN,SH2B1,CRY2,SDC3,SRGAP3,TMCC2,KBTBD11,SLC12A6,ATN1,DYRK1A,EGFR,PLXNC1,ELAVL2,ELN,ERCC2,OLFM1,FHL1,GPR153,GAD1,GAD2,SEPT9,SRCAP,AHDC1,LYVE1,GRIK5,ICA1,TJAP1,INPP5B,KCNH2,MAP4,MMP16,MYT1,NF1,CDK18,PLCD1,SAMD9,RIPOR1,ZSCAN2,SLC1A2,WDTC1,DOK5,TSPYL2,NPAS3,THSD1,STX1A,ARC,TRPM2,WIPF1,SCG2" Drug 2865_UP Resveratrol [501-36-0]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "ASPHD1,ADCY2,ADORA1,ALK,APLP1,PPP4R4,RGS20,PLA2G4C,SCAPER,THSD7A,CDH2,ADGRG1,TPP1,CRMP1,SIPA1L1,ERC2,SPOCK2,ARMCX2,SHANK1,HSD17B14,ERCC2,NCALD,BAIAP2,SEMA4D,FYN,ALDH1L1,SRCAP,RND1,GPER1,PCLO,HLF,HTR2A,ICA1,ITIH2,MGAT3,AFDN,CDK18,SERPINI1,RPS6KA2,EMID1,ZNF821,SLC1A7,FAM214B,PKNOX2,COA1,KDM4B,ZCCHC24,IQSEC2,SPART,VAMP1,CUX2,SZT2,SLC44A1,TK2,DAAM2,FAM155A,VLDLR,LAT2,SLC30A3,ITM2C,PLSCR4,CAMK1G,ADAMTSL3" Drug 3991_UP Carbarsone [121-59-5]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.94E-09 2.91E-04 4.85E-07 5.51E-06 63 195 "PKP4,PPFIA3,PPP4R4,STX16,NRP2,CACNA1I,BTRC,CACNA2D1,CBS,MTMR7,CBFA2T2,CDC42,ENTPD4,HAPLN1,CSF1R,LRIG1,SUSD5,CNTNAP2,SEC14L5,NTM,RABGAP1L,ATN1,DUSP9,EFS,ZNF391,NRN1,ZMYND10,KIAA1109,B3GAT1,HBS1L,MSTN,ADAM28,GRIK2,PADI2,KHK,MAN2A2,TM6SF1,MMP16,ADAM22,NF1,OMG,PCSK5,PDE3B,LRRN3,PKN2,DIRAS2,DOCK10,FUZ,PREX2,SNCA,PDZRN3,RBM26,EXOC7,OBSL1,TNS1,PDIA2,VAV2,VGF,VIPR2,ZNF24,WNK1,PHTF2,DPF3" Drug ctd:D002118 Calcium CTD 6.25E-09 3.06E-04 5.09E-07 5.79E-06 127 495 "ASIC1,ADCY5,SLC12A5,ADRA1D,ADRA1B,ADRB2,PCDH19,AGT,PLA2G6,TAOK1,PARG,APP,ARRB2,ATP1A1,ATP2A2,ATP2B1,CDK5R1,BTK,CACNA1I,CACNA1G,C5,CA4,CACNA1A,CACNA1B,CACNA1D,CACNA1E,DDR1,CACNA2D1,CALB1,CALM1,NGB,CAMK2D,USP2,CD38,CDC42,CACNA2D2,CHRM1,CHRNA4,CHRNB2,NRXN1,SLC24A2,CNR1,PICK1,CP,CDC42BPB,CSNK1G3,CYBB,DMD,NR1D2,DRD1,FIS1,EDN1,EDN3,EDNRA,EGFR,F8,CACNG2,PTK2B,FGF1,FGFR1,CAMKK2,GABBR1,GFAP,GHR,GNAS,GRIA1,GRIA2,GRM1,PTGDR2,HRH3,HPCA,HSP90AA1,HTR2A,IGF1,IL6ST,ITIH2,JAK2,KCNH2,KCNJ11,KCNMA1,KCNN2,KCNN3,STMN1,MYL3,MYO5A,NEFM,NF1,NOS1,NUCB2,OGDH,OXTR,P2RX7,P2RY1,PAX6,ABCB1,PIK3CD,PKD1,POU6F1,PPARA,PRKCB,PRKCG,MAPK3,MAPK4,PTAFR,PTH1R,RALGDS,RGS4,RYR1,RYR3,SLC8A2,SLC8A1,SLC8A3,SNCA,SPP1,SPTAN1,APOM,SYN2,SYT1,TAC1,TACR1,TJP1,TRPC1,TRPC3,TRPM2,UBTF,BEST1,IFT88" Drug 2539_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.38E-09 3.12E-04 5.18E-07 5.90E-06 62 191 "NR0B1,C1QTNF1,C1QTNF3,EPB41L5,ALDH4A1,SLC4A4,FGF17,NRP2,GYG2,BAIAP3,LDLRAD4,MAP7,CD86,B4GALT6,STOML1,FAM149A,CDC42BPB,CREM,TMCC2,SIDT2,PLXNC1,ING4,ZNF44,SIGLEC8,NEU3,LYVE1,GNAL,GRK4,RASSF8,ATXN2L,HTR2A,KCNMA1,MEF2C,ADAM22,MYO6,NINJ2,OPCML,PDE4B,CCSER2,SEPT4,POU6F1,MAPK10,PROX1,ROBO1,EMID1,SYNDIG1,SCN2B,SH3BGR,SH3BP2,ASAP3,SMTN,KANSL3,SPTAN1,TROVE2,MAPK8IP3,ACSBG1,SYT5,DNMBP,RALYL,SEZ6L,WNT7A,ZBTB38" Drug CID000004914 procaine Stitch 6.44E-09 3.15E-04 5.22E-07 5.94E-06 53 153 "ASIC1,ACHE,BCHE,CACNA1I,CACNA1G,WASF1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,ASIC3,CHRM1,CHRNA4,CHRNB2,GRIN3A,CACNG7,TUBD1,CACNG3,CACNG2,TUBB3,TUBB4A,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,TUBA8,TUBA1C,TUBB2B,MYL3,PKD1,PRKCB,PRKCG,PKN2,PRKCZ,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TPCN2,TUBB2A,TUBB1,TUBA1A" Drug 2474_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.83E-09 3.35E-04 5.43E-07 6.18E-06 61 187 "ADD2,MTUS1,SRPX,BIN1,ANK2,APBB2,SEMA4G,ST3GAL5,HIP1R,LHX2,ZFYVE9,DNAJB5,SULT4A1,RAB26,WHRN,CREM,FEZ1,DOCK4,KIAA0513,RIMS3,DNAJC6,OPTN,ABI2,LPAR6,ATP8A1,FER,OLFM1,FGFR1,GABRA4,GATM,ADAM28,RUNDC3A,STON1,PCLO,GRIK5,PADI2,KLF12,HTR2A,ITGAM,KIF5C,MARK1,MEF2C,NCAM1,PCDH9,SERPINI1,PLCL1,PMP22,BEND5,TTLL7,ZFHX4,ANKRD6,TMCC1,UNC5B,INKA2,RGL1,STXBP1,CAMSAP2,ATP13A2,TPM1,LAMP5,FZD3" Drug 3077_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.83E-09 3.35E-04 5.43E-07 6.18E-06 61 187 "ASPHD1,ASIC1,ABHD6,ANK3,APBB2,ARHGAP5,CCDC181,SGCE,HIP1R,CHN2,LHX2,DNAJB5,ABCG1,FEZ1,SUSD5,PDE4DIP,DZIP3,DOCK4,KIAA0513,RIMS3,DNAJC6,GSDME,SV2A,DLG4,EFNA3,PLXNC1,C3orf18,RASGRP2,STX2,ETV1,TLR7,ATP8A1,FGFR1,KIF5C,MAP4,SCAMP5,GIT1,MSI1,MYO6,NCAM1,CNOT4,PCDH9,SERPINI1,PLCL1,SIDT1,TMEM255A,WLS,SATB1,CCDC92,SLC1A3,SNCA,TNIK,PEG10,ZC3H13,RGL1,WWC1,TRIM2,PSD3,TMOD1,MAP3K12,SLC17A7" Drug 3677_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.83E-09 3.35E-04 5.43E-07 6.18E-06 61 187 "SLC12A5,ARRB1,BMP7,MAP7,NEURL1,CRLF1,TAOK2,RAB26,CREM,AKAP12,CSF1,FEZ1,CSNK1E,CTH,CTNND2,EDRF1,PITPNC1,SRGAP3,ARNT2,HS3ST2,PLXNC1,EPHB1,IGSF6,ZNF391,ETV1,RASL12,CAMSAP1,AGAP2,FYB1,SIGLEC8,ATP8A2,CSDC2,GNAL,GPD1,GPM6A,GRIK2,IGFBP1,SCIN,ITPKA,MBNL1,TAGLN3,MYBPC1,NPTX2,PDE4B,PDE4D,PDGFRA,SMOX,FA2H,POU3F4,PPP2R2B,PTHLH,PID1,SLC8A2,SLCO1A2,ATP10B,INKA2,ADGRL3,TBL1X,PCDHA6,SPHK2,SEMA3B" Drug 4005_DN Suprofen [40828-46-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "ASIC1,ADRA1D,C1QTNF1,GAS7,APP,LGR5,CDK10,DNAH17,C5,CACNB2,RAB28,WHRN,COL9A3,SH2B1,CTIF,ATN1,EDNRA,MBNL2,MTSS1L,ETV1,FOXG1,SEMA4D,DLL3,ZNF44,TRAF3IP2,TMEM8B,DISC1,POLL,GRM1,GRM8,ICA1,SHISAL1,MN1,NFYA,CNOT4,PBX1,EPN1,PRPH,SAMD9,RALGDS,ZCWPW1,SUGCT,KIRREL1,SELL,ZNF821,ZFP30,SLC1A7,PPP4R3A,SLC6A9,ZNF667,SMARCD3,TSNAXIP1,IQSEC2,DDN,MAPK8IP3,TCF4,SYNE1,TIAM1,TK2,CABIN1,RPRM,LMF1,SEMA3B,KCNAB1" Drug 6128_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "ADCY2,BCAR3,APBA2,APC,CDK10,ALDH4A1,ADGRB1,RUNX1T1,ABCG2,HOMER3,RIMS3,ING4,SRPK3,ERBB2,EYA1,HPCAL4,C1orf61,AGAP2,NSG1,GABRA2,ZMYND11,SRCAP,KCNMB4,GPD1,GPM6B,STON1,GRIN2C,SOX21,MDFI,SHC3,MID1,MMP16,SAMD14,NRCAM,NTRK2,P2RY1,PNMA3,CNNM2,PSD,BCAS3,TMEM231,RFX2,CARF,RYR1,ZNF365,SLC1A3,FAIM2,PALLD,TMCC1,KDM4B,DOP1A,IZUMO4,TSPYL2,MAPK8IP3,KAZN,WWC1,TCF4,CRTC1,ATP13A2,TJP1,VAV2,LMF1,KCNK12,SH3GLB2" Drug 3840_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "NDRG2,ADORA1,AGT,PLA2G6,ALK,TRMT9B,KCNAB2,AQP4,SEMA4G,CACNA1I,CFAP410,CBFA2T2,CPS1,IPCEF1,RASSF2,KIAA0319,SV2A,TMCC2,TRAPPC9,DRD1,DTNB,EDN1,SGK2,AGAP2,GAB1,SRCAP,HLF,ELOVL5,KCNJ5,KCNK2,CD200,MYH7,NPY,OMG,PCDH8,TMOD2,CDK14,PIK3CD,PLTP,PTCH1,PTPRD,PTPRH,KCNIP1,CPEB3,PKNOX2,SLC9A5,SLN,LIMCH1,RBM34,KDM4B,ZCCHC24,TSNAXIP1,ARHGAP26,SPART,SSTR2,ARC,POPDC3,TK2,UCHL1,PDIA2,FLRT2,VGF,LMF1,PAK5" Drug 3907_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "ARID1A,NDRG2,PLA2G6,MRTFA,BIN1,KCNAB2,CDK13,MARK4,SLC4A4,CA4,CAMK2B,VAX2,WHRN,EDRF1,SLC12A6,ATN1,DTNA,HIPK3,EGFR,MRNIP,ERCC2,FER,FHL1,C1orf61,TRMO,SRCAP,RUNDC3A,GLYR1,LIG4,MAOB,MAP2,MMP17,BCO1,NEK1,NF1,NUMA1,OGG1,PRKCB,PTK2,RAB3A,CEP97,RAD52,MSANTD2,RGS12,SBF1,SLC9A5,SLC15A2,BTBD7,SMARCD3,ARHGAP26,ATP11A,KIAA0930,AP4E1,ZNF34,THRA,TK2,MICAL1,ZIC3,ZNF24,SYNC,ITM2C,UBE3B,SSPN,SENP7" Drug 1524_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "AK2,TRMT9B,APC,APOC1,ATP6V0A1,ADAM23,FGF17,NRP2,CFLAR,SYNJ2,SCAPER,HAP1,CDH8,ARHGAP33,ASIC3,PLAA,HOMER3,WHRN,SLC4A8,CNTNAP2,DOCK4,RASSF2,MFAP3L,RCAN1,FRY,EFNB3,EGFR,SRPK3,ERCC2,FGFR1,ATP2C1,GPR153,HBS1L,ADAMTS13,GRIK5,HNMT,HSF2,KCNK2,VWA5A,MAP4,CD200,MYH6,NF1,NPTX2,SLC25A23,MAPK10,PRODH,PRPH,CEP97,RAD52,SEC61A2,ITSN1,ARHGAP26,ZBTB43,PSD3,CRTC1,HEY1,BEX4,TNS1,TPD52,TRIO,WNK1,MPPE1,KAT6A" Drug 1674_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "DPF1,ADRA1D,AMH,AMPD3,ARHGDIG,MARK4,ATP2A2,CFAP410,CA12,ZMYM4,ADGRG1,SLIT2,RAB28,SLC4A7,SH2B1,ARHGEF4,CDON,COQ7,BAIAP2,SEMA4D,CGREF1,ERAP1,GCNT2,TXNL4A,GNG3,GNG4,SLC2A6,ATXN2L,IL6R,KCND3,KCNJ5,KIF5C,MAP4,MBOAT7,PPP3CC,PRKAR1B,MAPK7,PRPH,ELOVL2,PTN,PLEKHB2,RAD51D,RGS10,RGS12,TCP11L1,SLA,BTBD7,SMARCD3,TSNAXIP1,KDM4C,CEP68,PLCB1,SYN2,SYT5,SMG6,TCF7L2,TRIM2,TRIO,VAV1,LAT2,ZNF45,NDRG4,KCNAB1,PHTF2" Drug 6023_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "SYN3,ACTN2,AMPH,BIN1,APOC1,SLC4A4,CADM3,FUBP1,GYG2,CACNA1I,LDLRAD4,CCKBR,CDH2,CBARP,TAOK2,SH2B1,AATK,VCAN,PDE4DIP,GREB1,SPOCK2,CNIH3,ATN1,DYRK1A,EFNB3,ELAVL3,HSD17B14,KCNMB2,STX2,HPCAL4,KHDRBS3,FYN,GCNT2,HPGDS,GNAO1,GRIK1,NXPH3,TJAP1,KCNMA1,VWA5A,ADAM22,TAGLN3,NOS1,NTRK2,OPCML,PDYN,PLCL1,EPN1,EMID1,ZFP2,HKDC1,SLC1A2,PKNOX2,SLC9A5,RIMS1,ZNF415,WDTC1,SOX2,TNIK,CAND2,BEX1,TBCEL,HEY2,SPHK2" Drug 6753_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "SLC12A5,ADGRF5,EPB41L5,GAS7,SLC4A4,MTMR3,CFAP410,CACNG1,CAMK2A,HIP1R,SYNGR3,ARHGAP33,CACNA2D2,SUSD5,DAPK3,C2CD2L,PLPPR4,SGSM2,DMPK,ATN1,SIDT2,ING4,COQ7,APC2,CEND1,FLT1,AFF2,B3GAT1,GABRA2,GAP43,TMEM8B,SIGLEC8,GLS,GNAL,GPM6A,GPR22,PADI2,IL11RA,KCND3,MSI1,MX1,NOVA2,OGG1,P2RY1,POLG,DCHS2,PTPRN2,TMEM231,RET,ZFP30,SLA,SLC9A5,ZC3H13,BEX1,SPTAN1,CEP68,PCDHGA10,TK2,TPM2,CADM1,PARP6,PARP11,EPM2A,DPF3" Drug 4985_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "DOC2A,EPB41L5,RGS20,MARCH3,MTMR9,CAMK2G,RCBTB2,SLIT2,LHX2,ZFYVE9,NECTIN3,FEZ1,ARHGEF4,RABGAP1L,RCAN1,SORBS3,EIF5,IRAK4,MRNIP,FHL1,ANKFY1,TPK1,INPP5K,GHR,GPR19,PCLO,GRIK5,CACFD1,DHX35,ITPKB,JAK2,KCNJ3,LMO2,VWA5A,MAPT,KITLG,MPP2,GIT1,ZNF862,NAP1L2,NDUFA5,NEK1,PCDH9,PDE4A,PPP2R5C,CEP97,ATG16L1,SUSD4,ROM1,IL17RB,PPP1R9A,ANKRD6,SLC1A7,EPN2,ZCCHC24,ARHGAP26,THSD1,STX1A,SEMA4A,ROBO3,FAM155A,SPHK2,EVI5,EPM2A" Drug 4377_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "RALGAPA1,NME5,LTBP4,DOC2A,BIN1,CDC42BPA,GAS7,APLP1,PPP4R4,CFLAR,SCAPER,SGCE,CACNA1I,LDLRAD4,CALB2,CRLF1,CHRNB2,CNTFR,WHRN,CSF1,HIPK3,ING4,RASGRP2,OLFM1,FGFR3,FOXG1,SEMA4D,TRAF3IP2,HBS1L,DISC1,ALDH1L1,PCDH17,TDRKH,RASSF8,ITIH2,VWA5A,MAP2,TM6SF1,MIA2,MID1,PLXNB1,STRN3,LRP12,PTAFR,RGS10,RGS12,GSTCD,TCP11L1,SEC14L1,SLC9A5,MAPKBP1,TMCC1,JMJD6,PLCB1,ROBO3,SMG6,KIAA0930,ZEB1,CRTC1,THRA,TNS1,RUNDC3B,GDPD5,EPM2A" Drug 3760_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "SYN3,NDRG2,ADCY2,KIDINS220,AP2A2,ANK2,KCNAB2,BRINP2,MYOM1,ADAM23,CALB2,RUNX1T1,SYNGR3,CDH8,CHI3L2,RAB33A,ZFYVE9,AKAP6,CSF1R,GREB1,MFAP3L,SV2B,ARNT2,DTNB,EFNA3,ING4,EPB41,CDKL3,ST3GAL6,SEMA4D,ERAP1,ATP8A2,GNAL,GPR17,GRM8,C2orf72,IL6R,ADAM22,NUMA1,PBX1,GPR173,PLP1,SPATA6,PRKAR1B,PTPRO,TMEM100,RYR1,SALL1,TRIM46,SUPT20H,PREX2,SHANK2,SLC14A1,SNCA,PDZRN3,SS18,SYP,CRTC1,PCDHA5,TNS1,TRPC1,FLRT2,VAV1,ADAMTS9" Drug 3752_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "RALGAPA1,MTUS1,LTBP4,PKP4,BRSK2,SYNGR3,SULT4A1,IFFO1,TCEAL2,ABCG1,FEZ1,CTH,RIMS2,MAML1,DLG4,ATN1,EFNA3,ING4,ELN,NCALD,CDHR1,APC2,ETV1,FABP7,KAT8,KIAA1109,FGFR1,PDLIM5,IQGAP2,RND1,GRM8,ADAMTS6,KCNB1,MAN2A2,MARK1,ADAM22,NEUROD1,SLCO1C1,NTRK3,NUMA1,PCDH9,PDE3B,PDE4A,SERPINI1,MAPK10,MASP1,PTAFR,ZCWPW1,RASGRF1,GAL3ST4,ZMAT4,RGS10,STUM,CPEB3,DZIP1,SLA,PREX2,MAPK8IP3,COBL,ADGRL3,TMOD1,PDIA2,ZNF225,KCNAB1" Drug 3182_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "TKTL1,ADORA3,AGT,ALK,AMPD3,KCNAB2,APLP1,CDC14B,CDK13,N4BP2L1,CDK5R2,CHN2,NRXN2,SULT4A1,RIPOR2,BRINP1,DLG4,ATN1,EDNRB,C3orf18,LRRC17,DLC1,KHDRBS3,NSG1,DISC1,RND1,TDRKH,NR3C1,GRM3,KCNB1,KCND1,KCND3,MATN3,AFF1,ZNF862,MYT1,NF1,PLTP,CDIP1,POU3F2,POU6F1,PTN,RADX,GAL3ST4,MYH14,PRR5L,SCN2B,PKNOX2,SHANK2,MYH15,SOX10,ROBO3,TLL2,PIK3R5,TRIO,TRO,WIPF1,ZIC3,ZNF45,SYNC,NT5M,SCG2,SEMA3B,ITM2C" Drug 2894_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "ASIC1,PLA2G6,ALCAM,CDK13,ASCL1,SLC2A11,GYG2,CA4,CACNB2,HAP1,FOXN3,CHI3L2,CHN2,TENM4,ATRNL1,VCAN,CNTNAP2,JAKMIP2,CNIH3,MAGI2,RABGAP1L,TMCC2,FRY,EGFR,MBNL2,ELAVL3,FOXG1,IQCG,NSG1,SRCAP,RND1,GLS,PRUNE2,GPER1,KCNN2,LMO2,NF1,NPTX2,NUMA1,PDE4B,SLC25A23,LRP12,VPS13C,ZSCAN2,KCTD17,NEK11,SH3BP2,KANSL3,BTBD7,COA1,KDM4C,IQSEC2,MAPK8IP3,ARC,DMXL2,ARHGEF12,R3HDM1,TPM2,RUNDC3B,TRO,XRCC4,NT5M,EVI5,ITM2C" Drug 2272_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.89E-09 3.38E-04 5.43E-07 6.18E-06 64 200 "SYN3,KLRC4,AK2,APC,RHBDL1,CDO1,WHRN,TCEAL2,CPS1,CNTNAP2,RIMS2,HDAC9,SPOCK2,CTIF,DYRK1A,MBNL2,IGSF6,EFS,FGFR1,GAD1,C1QL1,RND1,GLS,PRUNE2,GPM6A,PRDM5,GRM7,RASSF8,PTGDR2,ITGAM,KCNC1,KCNJ5,KCNN1,MEF2C,ADAM22,PFKFB2,CDK14,PIK3CD,POU3F4,MAPK8,RAD52,RGS10,ZFHX4,RYR1,ASAP3,SLC1A2,SLC2A5,PKNOX2,CXXC4,HECW1,ARHGAP26,CDK19,ATP10B,JMJD6,ARC,WSCD1,HIF3A,HEY2,TPM3,VAV2,SLC13A3,NT5M,SLC17A7,KCNAB1" Drug 6179_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.29E-09 3.57E-04 5.65E-07 6.43E-06 60 183 "ADD3,NME5,BIN1,APBB2,CDC14B,ALDH4A1,HIP1R,INA,CHN2,DNAJB5,WHRN,PDE4DIP,KIAA0513,RIMS3,DAPK3,DNAJC6,PARD6A,OPTN,EFNA3,MRNIP,ENO2,LRRC17,TBC1D16,TUBB4A,TESK2,FGFR1,PCYOX1,IQCG,GATM,PCDH17,RND1,GLS,RAB40B,PCLO,PADI2,DIPK1A,KHK,KIF5C,MYO6,NCAM1,PCDH9,SERPINI1,RETREG1,TMEM231,TMEM255A,RPS20,SH3BGR,SMARCD3,PALLD,ZSWIM8,ELOVL4,RGL1,STXBP1,CAMSAP2,TRIM2,RPGRIP1L,WDR7,ATP13A2,HEY1,SLC17A7" Drug 6434_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.29E-09 3.57E-04 5.65E-07 6.43E-06 60 183 "ADD3,MARK4,BMP7,BAIAP3,SPAG9,CLGN,PLEKHB1,DNAJB5,WHRN,AKAP12,PDE4DIP,DOCK4,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,FAM13A,RASGRP2,ACSL4,TUBB4A,DPYSL4,FYN,HBS1L,CYP46A1,GLS,RAB40B,RNFT2,ACOT7,KCNN2,KIF5C,MAP2,NEK1,PCDH9,SERPINI1,PIK3CD,PRPH,RPS6KA2,SH3GL3,ASAP3,WDR47,PKNOX2,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,BEX4,RBFOX2,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 3726_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ACTN2,NDRG2,ADORA1,LTBP4,APAF1,APBB1,ASPH,RASL11B,ALDH4A1,KIF1A,NRP2,BMP7,CACNG1,USP2,CHI3L2,CHRNB2,CLCN4,TPP1,SULT4A1,CNTNAP2,EDRF1,CTIF,DSCAM,EDIL3,FCF1,SEMA3D,EGFR,COQ7,NCALD,CACNG2,FGF1,ARFIP1,ADAM28,GLUL,POLL,GPR19,GRK4,KLF12,MATK,MEF2C,CD200,NF1,SLCO1C1,NPTX1,CLDN11,PDE2A,PDE4B,PDE4D,PTPRN2,CCDC40,RAD51D,RFX2,TRIM46,SH3BP2,SCN3B,TNIK,KIF21B,SPTAN1,MCF2L,AHCYL2,TNS1,PRDM2,PLSCR4" Drug 3695_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "C1QTNF3,ALK,AMPD3,AMT,APBB1,CDK10,PPP4R4,ARRB2,SCAPER,BAIAP3,TAOK2,RAB28,NRXN3,CNTN1,TCEAL2,CREM,SH2B1,CREB5,EDRF1,ATN1,DTNA,EFNA3,IRAK4,LRRC23,CORO2B,SCARA3,GNG4,GPR17,TJAP1,KCNJ5,KCNMA1,KHK,MEIS1,TAGLN3,ZNF862,NDUFA5,OCRL,PDGFRA,FSD1,CEP41,PRPH,PTN,PTPRB,RGS10,SCN8A,IL17RB,PKNOX2,SNCA,DOK5,KDM4C,SS18,ARC,ASTN2,MCF2L,KIAA1107,DNAH7,GPR161,CDK20,METTL3,CADM1,ZBTB14,MPPE1,DPF3" Drug 5736_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "DPF1,NDRG2,TRMT9B,EPB41L5,AQP4,ARRB1,ALDH4A1,N4BP2L1,GYG2,CACNA1I,BAIAP3,CACNG1,CDH8,PLEKHB1,RAB26,ARHGEF6,HAPLN1,CTIF,MFAP3L,SPOCK3,NTM,ING4,ELAVL3,EZH1,NRN1,DLC1,KAT8,FGFR1,FOXG1,NEU3,GPR162,TDRKH,GRM1,GSTM5,IL6ST,INSM1,JAK2,MEF2C,MYH3,ODF2,PBX1,PDE4D,SPATA6,TNPO2,PPP5C,MAPK10,VPS13C,ZSCAN2,TMEM255A,ACSS3,KHDRBS2,CNKSR2,SLC1A7,PREX2,SLC11A1,HECW1,IQSEC2,ATP11A,MCF2L,AMACR,SPHK2,PRDM2,SENP7" Drug 6435_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "LTBP4,FAM131A,APP,PROM1,BAIAP3,CALB1,SCARB1,ARHGEF2,PLEKHB1,RAB33A,DNAJB5,HOMER3,CHD1L,VCAN,SRGAP3,EFNB3,ZIC4,FGFR1,B3GAT1,TMEM8B,ATP8A2,ADAM28,POLL,GPM6A,GRB10,GRM7,ACOT7,HTR2A,L1CAM,MEIS2,CD200,PFKFB2,RELN,PTPRE,PTX3,ENOX1,RPS6KA2,RYR3,SATB1,ATXN7,SCN3A,CXXC4,SNCA,FAIM2,KDM4B,SOX11,DOK5,ATP10B,PHLDB1,TBL1X,SYNE1,RBFOX2,RUNDC3B,ZMYND8,MICAL1,NSD2,SPHK2,ADAMTS9,KCNAB1,SLC17A6,PLSCR4,NUP214,RNF146" Drug 5979_UP PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "MTUS1,BEGAIN,DOC2A,APAF1,ARHGDIG,SLC4A4,CADM3,NRP2,MYRF,BAIAP3,IL33,BTRC,CACNA2D1,CDC42,MAGI1,ADGRG1,HOMER3,PICK1,NCOR2,CSF1,VCAN,CTIF,EDNRA,SGK2,EFNA3,ING4,EPHA5,ETV1,SCML2,C1QL1,GNAL,GPR17,GPR19,STON1,KLF12,HLF,ICA1,TM6SF1,PALM,PBX1,CDK18,PENK,BCAS3,RASGRF1,KCTD17,KIRREL1,FBXW7,EMID1,IL17RB,ASAP3,AMBRA1,SLCO1A2,ZHX3,KDM4C,TROVE2,CRTC1,AHCYL2,TK2,RUNDC3B,TRO,WIPF1,MAP3K12,PCBP4" Drug 5758_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "SEMA7A,APBB1,PRX,ATP1A2,ATP2B2,ST3GAL5,BAIAP3,CAMK2A,BRSK2,SYNGR3,DLGAP2,PLEKHB1,SLC24A2,COL9A3,CREM,ABCG1,CSF1,C2CD2L,SV2A,RABGAP1L,DNAH9,EDNRB,EFNA3,CELSR3,PLXNC1,ZIC4,TUBB4A,CAMSAP1,HPCAL4,FOXG1,SYT17,PRUNE2,GRIK5,KLF12,TJAP1,JAK2,KHK,VWA5A,AFDN,PFKFB2,PLXNB1,C19orf57,LRRN3,ZSCAN32,PTPRD,KHDRBS2,PRR5L,SH3BP2,SLC8A1,SLC11A1,ZC3H13,AJAP1,VAMP1,SEMA4A,TAL1,DOCK9,PCDHA6,SLC44A1,AMACR,RPRM,PRDM2,SLC17A7,PAK5" Drug 3732_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ACTN2,NME5,APAF1,APBB1,APC,GAS7,DNAH17,RASL11B,STX16,NRP2,BAIAP3,CDO1,TAOK2,HAPLN1,EDRF1,MYEF2,EXOG,HS3ST2,DSCAM,SEMA3D,EPHA5,HPCAL4,IQCG,GAD2,ADAM28,GNG3,GPR19,C2orf72,TJAP1,ITPKA,KIFC3,MAN2A2,PCBP3,PALM,PDE4D,PLXNB1,PKN2,PSMD13,CCDC40,RAD52,FAM184A,ZMAT4,CARF,RPS20,ZNF821,NLGN1,ZNF667,SOX2,IQSEC2,INKA2,PLCB1,COBL,TRIM2,TK2,BHLHB9,TMOD1,ZMYND8,CADM1,SLC13A3,ZNF154,KCNAB1,PLSCR4,NUP214" Drug 6647_UP Estrone [53-16-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ASPHD1,MRTFA,KCNAB2,PPP4R4,ARRB1,ZSCAN18,ATM,BACH1,HAP1,SCARB1,CDH10,ADGRG1,CHRNA4,SULT4A1,AKAP6,DCT,MFAP3L,C2CD2L,MAGI2,DSCAM,DTNA,IGSF6,EFS,ETV1,DLC1,OLFM1,B3GAT1,GABRG2,NEU3,RUNDC3A,STMN2,CACFD1,ADAMTS8,KLF12,HSD17B1,ITGA7,KCNB1,LSS,ADAM22,MYO7A,NELL2,NHLH1,NRCAM,P2RX7,PDE4B,EPN1,SPATA6,ZSCAN32,PTPRO,ENOX1,RNASEL,FBXW7,SYNDIG1,SNCA,KIF21B,SP4,SPTB,SYT11,PCDHGA10,HIF3A,R3HDM1,TPM1,ZNF24" Drug 3890_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "DPF1,NLGN4X,PLA2G6,BIN1,N4BP2L1,CACNG1,RUNX1T1,SEPT7,CDC42,CNTN1,SNCAIP,ATRNL1,SNPH,SPOCK2,DCT,DYNC1I1,RCAN1,ELN,KCNMB2,SPEG,CORO2B,DLC1,FOXG1,CAMKK2,CPLX2,PCDH17,CELF3,NXPH3,HRH3,KLF12,IRF8,TJAP1,IL6R,KCNA2,VWA5A,MEF2C,MID1,AFDN,ADAM22,MYT1,NNAT,OMG,PCDH9,PDE4A,EPN1,PDZRN4,CEP41,SAMD9,PTAFR,ELOVL2,GAL3ST4,KCNIP1,SORCS3,IZUMO4,PEG10,ZC3H13,NPAS3,INKA2,MAPK8IP3,ACSBG1,SYT11,SYN2,SLC30A3" Drug 4473_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "MRTFA,ARRB1,ATP1A3,ATP2B3,NRP2,CACNA1G,CD86,TAOK2,EPS15L1,CNTFR,WHRN,NCOR2,CSF1,PDE4DIP,RIMS3,MAML1,MFAP3L,MAGI2,MBNL2,PLXNC1,KCNMB2,ZNF391,REEP2,OLFM1,FYB1,FYN,ADAM28,GLI2,GRK4,GRM8,KLF12,ITIH2,KCNF1,MDFI,ADAM22,MT1M,NOS1,NTRK2,PDE3B,PDE4B,ENPP2,GPR85,EPN1,MAPK7,MAPK8,PTHLH,PTPRH,FAT4,KHDRBS2,SUGCT,TCP11L1,KCNIP1,MRAS,CNKSR2,NLGN1,ZNF334,TSNAXIP1,ZHX3,TK2,TNS1,CDK20,VIPR2,KAT6A" Drug 4434_UP alpha-estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ADORA1,APBB1,AQP6,ZSCAN18,ATP2B3,CADM3,N4BP2L1,KIF1A,HAP1,CBS,CHN2,TAOK2,TPP1,NCOR2,SDC3,SPOCK2,C2CD2L,SPOCK3,DSCAM,DTNA,EDN3,EPHB1,KAT8,BAIAP2,FOXG1,DPYSL4,GAB1,GABRA1,ERAP1,SIGLEC8,ALDH1L1,SRCAP,GPR75,LPAR4,GRIK1,GSTM5,HLF,PDE3B,RETREG1,PURG,POU6F1,FAM120C,RNASEL,KLHDC8A,ASIC4,ZNF821,STUM,PPM1E,NLGN1,SLC1A2,SLC2A5,PKNOX2,SLC6A11,SLCO1A2,INKA2,VPS13A,CRTC1,ZFPM2,CRB1,SLC26A10,ZNF154,SLC17A7,MVB12B" Drug 4443_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ACTN2,SEMA7A,N4BP2L1,CACNA1I,LDLRAD4,CAMK2B,RUNX1T1,CHI3L2,ABCG2,IFFO1,MYRIP,CRY2,ARHGEF10,GREB1,ARHGEF4,EDRF1,GIT2,DCT,SMG7,CHRDL1,ABCC9,EDN1,CELSR3,ABI2,ELN,CDHR1,ZIC4,FGFR1,CAMSAP1,FYB1,FYN,ALDH1L1,PCDH17,RUNDC3A,GLI2,GLYR1,GRM7,SYNPO,ITGA7,KCNH2,LIFR,LMO2,MAP2,AFDN,MYL3,NPPA,OXTR,PDE4A,PLP1,PPP5C,MAPK7,ACSS3,ZMAT4,RGS4,HSPA4L,PDZD2,OBSL1,CRB1,TPM1,TUB,LAT2,NT5M,KCNAB1" Drug 5849_UP Glibenclamide [10238-21-8]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "PKP4,APC,DDO,PPFIA3,ATP1A3,SYNJ1,ST3GAL5,SCAPER,CACNA1A,CHGA,RAB28,VAX2,HAPLN1,CSF1R,PDE4DIP,CNTNAP2,GPRASP1,SPOCK2,SV2B,DTNA,EFNB3,EGFR,DENND4A,ZNF589,TMEM8B,IL12A,KCNF1,KCNJ4,KHK,VWA5A,MDFI,AFDN,NTRK2,PPP2R2B,MAPK7,GRAMD1C,MASP1,RALGDS,C1orf54,SLC6A15,RGS12,ROM1,TCP11L1,KCNIP1,FOXRED2,ASAP3,FNDC3A,SLC1A7,SLN,ZNF667,IFT122,TMCC1,BEX1,THSD1,MCF2L,PCDHGA10,TIAM1,SEZ6L,RUNDC3B,VAV2,REEP1,KCNAB1,TIGD6" Drug 833_UP 5255229; Up 200; 13uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "NDRG2,NR0B1,APP,AQP4,ARHGDIG,SLC2A11,BACH1,SCAPER,MTMR3,GYG2,CFAP410,CACNA1D,SRSF11,RCHY1,CREM,ENTPD4,ABCG1,ATRNL1,CTH,ARHGEF4,RIMS2,PPP6R2,DBT,DLG3,BAIAP2,SYT17,GRK4,CNTRL,GRM8,MAP4K5,GPR45,LYRM9,NDUFA5,CNOT4,PALM,PDE3B,PIK3CD,PRKAR1B,MAPK7,MAPK8,PRPH,ZSCAN2,SUSD4,RNASEL,ROBO1,TCP11L1,SCN2B,ITSN1,FNDC3A,NLGN1,SMTN,BTBD7,DDN,CEP68,PHLDB1,VAMP1,SMG6,AHCYL2,ZNF34,TRIO,VIPR2,EVI5,ZNF248" Drug 4958_UP Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "SYN3,NDRG2,NME5,C1QTNF1,LTBP4,APBA2,APC,FAM131A,PPFIA3,SEMA4G,CDK13,SLC2A11,CADM3,GYG2,BAIAP3,CHI3L2,RAB33A,CSF1R,PLCH2,TMCC2,SIDT2,EIF4G2,ELAVL3,RASGRP2,ZNF589,FGFR1,SEMA4D,ERAP1,MSL3,GNG4,ICA1,KIFC3,MDFI,MOBP,NF1,SLCO1C1,OPCML,KCNK10,PDE3B,PDE4B,PFKFB2,PTPRB,KCTD17,KLHL11,MYH14,RPS6KA2,FRMPD1,FUZ,KANSL3,DOP1A,HECW1,ZC3H13,IQSEC2,CDK19,AJAP1,POPDC3,MCF2L,TRPC1,HIRA,LAT2,KLC2,SPHK2,NLRP3" Drug 3834_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ADORA1,SEMA6A,KCNAB2,SEMA4G,PLA2G4C,LDLRAD4,SLC16A4,CDO1,CHI3L2,NRXN3,FADS2,ARHGEF6,CNTN1,WHRN,TENM4,CTIF,ATN1,EGFR,ING4,ELAVL4,PTK2B,ZIC4,FOXG1,AGAP2,PDLIM5,GAD1,DISC1,SRCAP,ADAM28,CSDC2,C1QL1,PRUNE2,GPER1,ATXN2L,HTR2A,TJAP1,KCNH2,KCNJ4,KCNQ3,KHK,MAOB,TM6SF1,AFF1,MMP17,NOVA1,NOVA2,OMG,TMOD2,FAM120C,CPEB3,ST6GAL1,SLN,RGL1,POPDC3,TBCEL,DMXL2,CUX2,TRIM2,PCDHA5,SLC35G2,TRIO,PDIA2,SLC30A3" Drug 6338_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ASPHD1,ARID1A,NLGN4X,CDC14B,PPP4R4,MADD,CDK13,SLC4A4,STX16,KIF1A,CFLAR,ST3GAL5,CACNA1I,NRXN3,DNAJB5,AKAP7,SH2B1,AATK,CSF1R,CTH,RIPOR2,SIDT2,EFNA3,EGFR,FGF13,FOXG1,C1orf61,DISC1,ATP8A2,ZNF276,GLYR1,GLS,LPAR4,KHK,KIFC3,LIG4,MGAT3,MMP16,NF1,NNAT,NUMA1,CCSER2,RETREG1,STRN3,MINDY2,PRKAR1B,MAPK7,TMEM206,ATXN1,DZIP1,COA1,SMARCD3,IFT122,SNCA,TSNAXIP1,LHPP,PHLDB1,CRTC1,TIMP4,TK2,XRCC4,REEP1,STMN4" Drug 5568_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "DPF1,ADD2,ADRA1B,AGT,AMPD3,BIN1,APBA2,APC,PDXK,DNAH17,RASL11B,SYNJ1,CAMK2B,TCEAL2,CREM,GREB1,DOCK4,KBTBD11,DMPK,EGR3,ELAVL3,OLFM1,FOXG1,DCTN2,CAMKK2,FYN,CPLX2,ALDH1L1,RUNDC3A,GLYR1,GLS,GRM8,JAK2,KCNQ3,MAOB,TM6SF1,MMP16,MYCN,NOVA1,CDK18,PDE4A,PLCD1,VPS13C,PTH1R,ELOVL2,C1orf54,SGK1,SH3GL3,SYBU,SLC1A7,SLC9A5,SLC11A1,SNCA,SAMSN1,TAL1,AP4E1,HEY2,R3HDM1,UBE3A,WIPF1,LAT2,MVB12B,PHTF2" Drug 490_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "ADD2,KIAA1324,C1QTNF1,LTBP4,ALK,ANK2,AZGP1,GYG2,HAP1,CCK,NEURL1,CDH10,CHRNB2,TAOK2,IFFO1,CREM,SLC12A6,ATN1,DSCAM,SGK2,EFNB3,ELAVL4,RGS17,STX2,NCALD,ZNF589,SCARA3,GABRA5,GAD2,GART,RUNDC3A,GRIA4,GRIN1,PTPRT,GSTM5,FAM107A,GUCY1A1,KLF12,HMX1,KCNJ9,STMN1,ADAM22,MSR1,MYL3,NELL2,NNAT,NPPA,NTRK3,PDCD2,GPR173,RAD52,SUSD4,RGS4,ATXN2,SLC15A2,SMARCC2,SMARCD3,OBSL1,TNS2,TNS1,SEZ6L,WIPF1,SLC13A3" Drug 6194_UP genistein; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.43E-09 3.64E-04 5.65E-07 6.43E-06 63 196 "SYN3,C1QTNF3,BIN1,ANK2,AQP6,PLA2G4C,ARSE,CADM3,BTRC,CFAP410,CACNG1,RUNX1T1,CHN2,CREM,AATK,CSF1,MICAL2,SIPA1L1,PDE4DIP,KIAA0513,INTS1,SPOCK3,HS3ST2,EEF1A2,MBNL2,MRNIP,VPS13B,RASGRP2,ERBB2,OLFM1,HPCAL4,AGAP2,NSG1,GAD2,SIGLEC8,MSL3,GPD2,HTR2A,KCNMA1,MOBP,MYH7,NNAT,NRCAM,DUSP26,EPB41L4B,RGS4,RGS12,SLC1A7,SLC11A1,SNCA,IZUMO4,ZC3H13,ST5,JMJD6,TK2,SEZ6L,TRH,LMF1,VSNL1,SLC26A10,PRDM2,MARCH8,JPH3" Drug 7005_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.77E-09 3.81E-04 5.90E-07 6.71E-06 59 179 "ABHD6,ADD3,NME5,BMP7,ST3GAL5,SCAPER,GYG2,BTRC,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TSPAN5,EFNA3,EFNB3,ENO2,CDKL3,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KCNH2,KIF5C,MPP2,MXI1,PCDH9,PDE4A,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,LRRC49,RAB3A,SH3GL3,PPM1E,ASAP3,WDR47,CCDC88A,ZCCHC24,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,AGTPBP1,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,ZNF45,MARCH8" Drug 2794_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.77E-09 3.81E-04 5.90E-07 6.71E-06 59 179 "ABHD6,ADD3,ALCAM,ST3GAL5,BAIAP3,CBFA2T2,CLGN,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,TUBB4A,ATP8A1,HPCAL4,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,KIF5C,VWA5A,MAP2,MXI1,NAP1L3,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,SH3GL3,PPM1E,ZNF365,WDR47,PKNOX2,LIMCH1,ZCCHC24,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,POPDC3,TRIM2,HEY1,RUNDC3B,DNAJC12,ZNF45,REEP1,SLC17A7,ITM2C" Drug CID000000238 laevadosin Stitch 8.11E-09 3.98E-04 6.15E-07 6.99E-06 370 1800 "SYN3,ACLY,CLK4,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,BRAP,CDC7,ADORA1,ADORA2A,ADORA3,KIDINS220,AP1B1,NME5,AK2,TAOK1,ALK,MRTFA,AMPD2,AMPD3,MAP4K3,MYH7B,APAF1,APC,DGKZ,DGKD,CDK10,PDXK,MADD,CASK,ARNTL,ARRB1,CDK13,STK33,MARK4,DYNLL1,ATM,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,ATP6V0A1,RIPK1,KIF1A,BCS1L,FGF17,BMPR1B,NAE1,BTK,AP1M1,DDR1,CACNA2D1,CALM1,NGB,CAMK2A,CAMK2B,CAMK2D,CAMK2G,BRSK2,CARS,CCNH,CCNT1,P2RX6,CD38,ENTPD2,DGKI,CDK11B,LRBA,CDC25B,CDC27,DCLK1,UBE2L6,SRSF11,ASIC3,TAOK2,ZFYVE9,MYL6B,CLTA,CLTC,FADS2,ABCG2,CPS1,CREM,ABCG1,CS,CSF1R,FEZ1,CSNK1E,CSNK1G3,PLCXD3,ZFYVE16,EARS2,DGKB,DGKG,DAPK1,DAPK3,IP6K1,DCTN1,BLOC1S6,AK5,DMD,DMPK,NR1D2,GNE,DYRK1A,FARSB,ABCC5,ABCC9,E2F5,EDN1,SGK2,HIPK3,EGFR,LPAR6,EIF4G1,EIF5,IRAK4,TNK2,ENO2,EPB41,EPHA5,EPHB1,ERBB2,ERBB4,ERCC2,CDKL3,KATNAL1,ACSL4,TUBA1B,PTK2B,TUBB3,TUBB4A,TAOK3,ATP8A1,STRADA,TESK2,PPP1R1B,FER,FGF1,POLR1B,FGFR1,FGFR3,FGR,PRKAG2,POLK,ATP5PD,UBE2E3,IP6K2,VTI1B,FOXO3,FLT1,NELFCD,DCTN2,AK8,TPK1,CAMKK2,ATP6V1H,ATP2C1,BRSK1,FYN,GAB1,CAB39,NEK6,IP6K3,MTHFD2,ACSS1,GART,GCK,GGT7,GGT5,MALT1,GK,TTBK1,DBF4,GLS,GLUL,DCLK2,GNAL,GNAS,CNDP1,GPD2,ATF7,LPAR4,NUDT21,TUBA1C,RAPGEF1,PLCD4,CIT,MAP4K5,IRAK3,HBA1,HMGCR,HSP90AA1,MYLK2,IL11RA,TUBB2B,ITPKA,ITPKB,JAK1,JAK2,KHK,KIT,LIG4,SMAD1,MARK1,MARK3,MATK,MBP,MEF2C,KITLG,AFDN,STK32C,MTR,MYBPC1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,P2RY13,NDUFA5,NEK1,NME4,NOS1,NPY,NRGN,NTRK2,NTRK3,DDR2,KSR2,NUMA1,OGDH,P2RX7,P2RY1,PAK3,PC,CDK18,PDE3B,PDE4B,PDE4D,PDGFRA,PDPK1,PENK,PFKFB2,PFKFB3,PFKFB4,PFKP,CDK14,ABCB1,PHKG1,PIK3C2A,PIK3CD,PIK3R1,PKM,PLCB2,PLCD1,PLIN1,POLG,POLR2F,PRKAB2,PRKACB,CEP41,PKIA,PRKCB,PRKCG,PKN2,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRPSAP2,NDUFS7,PSMA6,SNRK,PSMD13,PTK2,RAB3A,ACSS3,RAD17,RET,REV3L,MYH14,RORB,NEK11,EPHA10,ATP8B4,RPS6KA2,STK32B,LRRK2,RPS20,HUNK,MAPK12,SARS,SELL,FOXRED1,SGK1,MYO18A,SEPHS1,SLCO1A2,MAST1,TNIK,KIF21B,NMNAT2,CDK19,SRPK2,MAPK8IP3,NEK4,TTBK2,ACSBG1,SUPT5H,ABCC8,PLCB1,SYN2,SYT1,ATP11A,TAF6,MLST8,TAF9,CNTN2,SMG6,TCEA1,ACSL6,CLASP1,SLC19A3,TEK,TIE1,TK2,TLR4,TMOD1,TNNT1,CDK20,NPL,TPM3,TPM4,TRPM2,TSC1,TSC2,TTPA,SGK3,TUBB1,UBC,UBE2H,UBTF,P2RY12,RICTOR,SPHK2,POLR3H,WNK1,MAP3K12,PRTFDC1,TUBA1A,WNK3,WNK2,NELFE,PAK5,CAMK1G,ACTR3B" Drug 2777_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.26E-09 4.05E-04 6.25E-07 7.11E-06 58 175 "ADD3,NME5,ALCAM,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,DOCK4,KIAA0513,RIMS3,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,MBNL2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,TDRKH,STON1,KIF5C,MITF,MXI1,NAP1L3,PCDH9,TMOD2,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,RPS6KA2,SH3GL3,PPM1E,WDR47,FAM214B,CCDC88A,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,NPL,RUNDC3B,DNAJC12,ZNF45,SLC30A3,GDPD5,SLC17A7,ITM2C" Drug 5733_UP Syrosingopine [84-36-6]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.57E-09 4.20E-04 6.47E-07 7.36E-06 61 188 "DPF1,ADD2,LTBP4,APAF1,ALDH4A1,ATP2B1,ADGRB2,ST3GAL5,IL33,CACNG1,CALB2,MAP7,CBS,SYNGR3,ARHGEF2,KCNAB3,ARMC8,SLC4A7,AKAP12,AATK,CTH,RIMS3,GIT2,FAM13A,LPAR6,ZNF391,FGFR1,FYN,ARPP21,RND1,STON1,GRB10,GRIK5,ELOVL5,JAK2,KIT,TAGLN3,MXI1,NTRK3,PBX1,PDE3B,PDE4B,PDE4D,STRN3,FA2H,MINDY2,PRPH,PTPRH,RALGDS,SH3BP2,FRMPD1,RBM34,SOX15,ZNF423,SPTAN1,PCDHA6,HEY1,PIK3R5,UBE3A,KCNAB1,SENP7" Drug CID000002834 AC1L1EKQ Stitch 8.62E-09 4.23E-04 6.50E-07 7.40E-06 26 52 "ADCY5,ADCY6,ADCY8,ADRB2,AMT,ALDH7A1,GNAS,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PDE3A,PDE3B,PTK2" Drug 4527_UP Rifabutin [72559-06-9]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-09 4.50E-04 6.69E-07 7.61E-06 60 184 "ABAT,MARCH3,NOL4,RGS9,ST3GAL5,BAIAP3,CA12,CAPN3,HIP1R,CRLF1,CHN2,ABCG1,VCAN,PDE4DIP,DNAJC6,PLPPR4,SRGAP3,ST8SIA3,EFNB3,FAM13A,IRAK4,TAOK3,FGFR1,DPYSL4,PDLIM5,PNMA2,FYN,GAD1,PCDH17,GLS,GPM6B,STON1,SOX21,GUCY1B1,DIPK1A,KIF5C,MAPT,MITF,PDGFRA,SERPINI1,RETREG1,GRAMD1C,PRPH,RGS4,SH3GL3,ASAP3,ST8SIA1,KIF13A,TNIK,BEX1,ARHGAP26,SAMSN1,ELOVL4,CEP68,RGL1,SYT1,COBL,TGFBR3,DNAJC12,PLSCR4" Drug 4347_DN Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ALK,AMPD3,BIN1,APBA2,ATM,CFLAR,SYNJ2,CA12,NEURL1,MAGI1,CHRNB2,STOML1,DNAJB5,TBC1D5,GIT2,MFAP3L,SMG7,RABGAP1L,DLG3,SLC12A6,DTNA,EFNA3,EIF4G2,MRNIP,RRAGB,FAM198B,AGAP2,GPR153,GCNT2,SRCAP,RUNDC3A,GRIK5,KIF2A,MAPT,MDM4,ZNF862,SLC11A2,RETREG2,RGS12,ZFHX4,RASA3,PEX26,EPN2,CXXC4,COA1,SMARCD3,KDM4C,ZBTB43,CLSTN2,PLCB1,ANKRD12,KIAA1107,TBL1X,WSCD1,ZEB1,ARHGEF12,CADM1,ZIC3,ZNF24,WNK1,ITM2C,KAT6A,GAN" Drug 3551_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ACTN2,ADCY6,KIAA1324,ADGRF5,SPARCL1,MRTFA,APBA2,APLP1,SEMA4G,PTCH2,SLC2A11,ARHGAP33,RCBTB2,ASIC3,CHM,ARHGEF6,CNR1,PDE4DIP,CNTNAP2,SNPH,CDON,ATN1,RCAN1,EFNA3,TENM1,ERCC2,VPS26C,F5,FOXG1,FYB1,FYN,GAP43,TMEM8B,GPM6A,GPER1,ADAMTS13,MAN2A2,MEF2C,MN1,NEUROD1,NPPA,PCBP3,CAMKV,PIK3CD,PLP1,LRP12,PPARA,MINDY2,RAB3A,RGS12,MYH14,RPS6KA2,SEMA6D,SH3BP2,FRMPD1,WSCD1,ZEB1,DOCK9,PCDHA3,R3HDM1,VAV2,ZIC3,GDPD5" Drug 4421_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "DPF1,ASIC1,NDRG2,KIDINS220,GAS7,APP,CDC14B,CDK13,ATP2B2,ADAM15,CACNA1D,CACNG1,RHBDL1,ASIC3,SNCAIP,RGS6,DUSP9,TNK2,RASGRP2,F5,ZNF589,KIAA1109,FHL1,GAD1,ALDH1L1,MSL3,GNAS,GNG3,ATF7,GPER1,GRIK5,GRIN1,GUCY1B1,JAK2,KIF5A,VWA5A,MAG,MMP17,MYO7A,NPY,PCBP3,CLDN11,PDE3B,PACSIN1,PPARA,CEP41,MAPK8,C1orf54,SCN8A,RASA3,SLC14A1,SOX2,DOK5,PCDHA5,HIF3A,GPR161,HEY2,TPM3,LAT2,KCNK12,SLC30A3,PARP11,PHTF2" Drug 4097_UP Gelsemine [509-15-9]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "NDRG2,PKP4,APC,APP,SLC2A11,BMP7,MTMR3,CFAP410,HAP1,CAMK2B,NEURL1,LRRFIP1,TAOK2,CLCN4,AKAP6,SUSD5,ARHGEF4,SEC14L5,SPOCK2,C2CD2L,DTNA,EDN3,SEMA3D,RASGRP2,CEND1,C1orf61,AGAP2,GABRB3,DISC1,NEU3,LYVE1,GNAL,GPD1,KLF12,HPSE2,IGF1,KCND3,KCNJ3,ADAM22,NTRK2,ENPP2,PIK3CD,CNNM2,MARCH1,CCDC40,KLHL11,PNMA8A,SEMA6D,ASAP3,PKNOX2,SNCA,SOX2,TNIK,RBM26,NFASC,TACR1,RIMBP2,SEZ6L,TUBB1,CADM1,AMOT,KCNAB1,NUP214" Drug 4760_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ASIC1,AMPD3,PPP4R4,PLA2G4C,PDE8B,ATP2B2,SCAPER,CACNA1G,CFAP410,CACNG1,ASIC3,TCEAL2,ARHGAP24,CTIF,SPOCK3,DMPK,EDN1,FAM13A,PLXNC1,ELAVL3,RASGRP2,PTK2B,SCARA3,FAM49B,SRCAP,GNG3,GPM6B,GRIK1,GRIK4,GRM7,ATXN2L,ICA1,KCND3,KIT,NTRK2,NUMA1,KCNK10,CDIP1,PKN2,MAPK7,PTAFR,PTHLH,ELOVL2,RFX2,MYH14,SH3BGR,ASAP3,PKNOX2,SLC6A9,ZNF334,NPAS3,TROVE2,JMJD6,SYP,ZEB1,TRIM2,CRTC1,PARD3,TPM2,VLDLR,SPHK2,SLC17A7,KCNAB1" Drug 4559_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ARID1A,MRTFA,AQP4,SLC4A4,KSR1,CACNA1I,IL33,B4GALT6,ZFYVE9,CLCN4,LY86,IFFO1,TCEAL2,VCAN,CNTNAP2,CTNND2,C2CD2L,AK5,CDON,ATN1,ST8SIA3,SIDT2,ING4,TNK2,RASGRP2,KIAA1109,FLT1,FYB1,GABRA5,GFER,GLRB,GRM8,GSTM5,JAK2,KCNJ5,MDM4,NPR2,NPTX1,PIK3CD,EPN1,PTPRH,KHDRBS2,TMEM206,CCDC102B,KCNIP2,KCNIP1,ZFP2,MRAS,RASA3,PKNOX2,SLC11A1,SLC12A4,SNCA,TSNAXIP1,NFASC,INKA2,ZEB1,TMOD1,TPM2,TRPC1,PRDM2,EVI5,SENP7" Drug 5054_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "C1QTNF3,APAF1,ATP2B2,MYOM1,ADAM23,ADGRB2,NRP2,ST3GAL5,CACNA1A,BRSK2,KYAT1,LDB2,DNAJB5,LY86,VCAN,PDE4DIP,DBT,MFAP3L,SRGAP3,SGSM2,ARNT2,CDON,EDN1,LRRC23,SPEG,CACNG2,FAM49B,OGA,GLI2,GNAO1,GPR17,GSTM5,GUCY1A2,PTGDR2,HPSE2,C2orf72,ITIH2,KIT,MATN3,KITLG,NCAM1,NUMA1,PDE4A,MAPK4,PID1,GAL3ST4,RNASEL,MYH14,IL17RB,ZNF334,SLN,KDM4B,SOX10,POGZ,PHLDB1,ADGRL3,TBCEL,RPRM,VSNL1,KCNK12,WNK1,PARP6,SLC17A7" Drug 6372_DN 3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "TRMT9B,CDK13,ALDH4A1,ADGRB3,CFLAR,BMPR1B,CACNA1I,MYRF,HAP1,USP2,CHRNB2,RAB28,CLCN4,QKI,AATK,CHD5,PDE4DIP,SMG7,RABGAP1L,EDN1,EGFR,ING4,ELAVL3,TNK2,ETV1,WAC,FGF1,CAMSAP1,ANKFY1,DCTN2,ZNF276,GPD2,GPR17,GPER1,TJAP1,KCNA2,MAPT,MATK,NTRK2,OPCML,PALM,PBX1,PDE2A,GPR85,EPN1,STRN3,LRP12,PACSIN1,KIRREL1,RPS20,SCN8A,SLC1A7,PEX26,RIMS1,WDTC1,ATP11A,TBL1X,CRTC1,ZMYND8,HIRA,LAT2,STMN4,MPPE1" Drug 3666_UP Riluzole hydrochloride; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ACTN2,APC,APP,CDK10,ZSCAN18,ADAM23,NRP2,BMP7,CACNA1I,CACNA1D,DLGAP2,ADGRG1,CNTNAP2,CTNND2,ST18,RIPOR2,RIMS3,MYEF2,MFAP3L,EXOG,RGS17,ELN,CORO2B,FGF12,AGAP2,SEMA4D,GABRB3,GAP43,SEPT9,ALDH1L1,GNAO1,GPER1,GRIA4,GRIK5,ITGA7,KCNJ5,KIFC3,LMO1,MARK1,MMP16,NNAT,NRCAM,PALM,PCSK2,PNMA3,SPATA6,POU3F2,RGS4,RNASE1,MYH14,RAVER2,CNKSR2,PDZRN3,SOX2,UNC5B,ZC3H13,SYT11,PLCB1,ADGRL3,PCDHGA10,TNS1,PRMT8,TRIO" Drug 5411_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ADD2,AP2A2,KIAA1324,PLA2G6,DOC2A,SEMA7A,CNTNAP1,APC,CDC14B,ADAM23,SGCE,CALB1,CDH10,DCLK1,ARHGAP33,CRLF1,LY86,WHRN,ARHGEF4,CYBB,PHYHIP,HEPH,GSDME,HIPK3,EIF4G2,VPS13B,ERCC2,RRAGB,PRELID3A,ADAM28,PCDH17,POLL,GPM6A,BACH2,TJAP1,KIF5A,MITF,MSI1,BCO1,MSR1,MYO7A,PDE3B,PFKFB2,PPARA,PPP5C,ZFHX4,SH3BP2,DOCK10,ST6GAL1,BCAN,PKNOX2,SLC11A1,SHANK2,SMARCD3,SOX2,ZNF423,SAMSN1,TBCEL,FLRT2,ZIC3,SPHK2,KCNAB1,SSPN" Drug 4097_DN Gelsemine [509-15-9]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "AMH,APC,PPP4R4,CDK13,ALDH4A1,ATP1A3,AZGP1,BRSK2,FOXN3,ARHGAP22,RAB28,ZFYVE9,DNAJB5,AKAP7,AKAP5,NCOR2,EDRF1,SPOCK2,MFAP3L,AK5,EDNRB,EIF4G2,IRAK4,LRRC23,MTSS1L,ETV1,ST3GAL6,ZNF589,KIAA1109,B3GAT1,OGA,GAB1,C1QL1,POLL,GRIK5,IL12A,ITIH2,P2RY13,NNAT,CCSER2,PLCD1,PLXNB1,POU6F1,ZSCAN2,SLC6A15,KCTD17,MYH14,ROM1,MRAS,FRMPD1,BCAN,SLC1A6,DOP1A,UNC5B,SPTB,VAMP1,SYP,PCDHGA10,GPR161,TK2,LILRA4,OSBP2,ZNF24" Drug 2188_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ADORA1,TRMT9B,BIN1,CDC42BPA,DDO,PPFIA3,AQP4,CDK13,ASCL1,LDLRAD4,TAOK2,STOML1,AKAP6,ABI3BP,PDE4DIP,SV2A,DSCAM,HEYL,FAM13A,ELAVL3,HSD17B14,EPHB1,ERBB2,FLT1,DLL3,ADAM28,GFER,GPM6B,SPACA9,GUCY1A2,SCRG1,KIF5A,MARK1,NEUROD1,NNAT,NPPA,NTRK2,OPRL1,PFKFB4,PLEC,EPN1,PMP22,POU3F2,PPP2R2B,RELN,RNASE1,STUM,RASA3,FERMT1,SLC1A6,EPN2,PKNOX2,SLC6A8,SLN,TMCC1,WDTC1,ZC3H13,SPTB,LMF1,CLIP2,XRCC4,PLSCR4,JPH3" Drug 2821_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "AK2,ALCAM,APBA2,APOC1,ARRB1,DNAH17,ATM,ALDH7A1,OSGIN2,BAIAP3,INA,CBFA2T2,WHRN,RCHY1,NOS1AP,EXOG,PHC2,STX2,KAT8,ZNF589,FGFR1,ANKFY1,OGA,HBS1L,GCNT2,C1QL1,TDRKH,GPER1,ADAMTS13,HSD17B1,ICA1,KCNQ3,MX1,NDUFA5,PLCD1,LRP12,POLG,CEP41,PRKAR1B,PRODH,SIDT1,PTCH1,RAD52,TRIM68,RXRA,PPP1R9A,CNKSR2,SMARCC2,ZCCHC24,EMC1,NPAS3,SPART,ABCC8,SEMA4A,ROBO3,SZT2,PCDHGA10,TK2,RUNDC3B,LMF1,LAT2,MAP3K12,SEMA3B" Drug 3836_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "SEMA6A,SEMA4G,ASPH,ALDH4A1,SLC2A11,N4BP2L1,ADGRB1,MTMR3,CACNB2,CAMK2B,CBFA2T2,SCARB1,NEURL1,ADGRG1,CHI3L2,CHRNA4,LHX2,ZFYVE9,SULT4A1,CNN3,AKAP5,CRY2,NCOR2,CNTNAP2,PHF14,DAPK3,SPOCK2,RABGAP1L,TRAPPC9,DYRK1A,EFNB3,ERCC2,C1orf61,AGAP2,AFF2,GLYR1,PRUNE2,ATXN2L,IL12A,KCNJ4,MAOB,AFDN,MMP16,SAMD14,NOVA2,PCBP3,NUMA1,GDAP1L1,ZSCAN32,RASGRF1,RASA3,ASAP3,PPP4R3A,KIF13A,PEG10,ZNF423,ZBTB43,INKA2,ARC,PDLIM2,ZEB1,TPM3,NUP214" Drug 7192_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ASIC1,AP2A2,PLA2G6,MRTFA,CDC42BPA,APOC1,CDC14B,ARNTL,ALDH4A1,SLC4A4,CFLAR,SYNJ2,SCAPER,BTRC,CAMK2B,ARHGEF2,CDH10,CHM,LHX2,FAM189A2,IFFO1,NCOR2,LRIG1,MFAP3L,PARD6A,SNX29,COQ7,DENND4A,DLC1,KAT8,OLFM1,BAIAP2,FHL1,TRMO,NEU3,GCNT2,GNAS,EML4,ITPKB,LIG4,MGAT3,LYRM9,NFYA,CDK14,RETREG1,STRN3,PROX1,PRPH,RALGDS,ATG16L1,ZFP30,SH3GL3,SYBU,SLA,PPP4R3A,EMC1,SPART,ELOVL4,TK2,TRPC1,ZNF45,SEMA3B,PHTF2" Drug 6803_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "SLC12A5,AGT,AMPD3,ATP2B2,CACNA1I,CDK5R2,CA4,ADGRG1,STOML1,LY86,NCAN,DAPK3,DBN1,CNIH3,PARD6A,EDNRA,EDNRB,SGK2,TNK2,DMTN,OLFM1,FGFR3,FHL1,HPCAL4,PDLIM5,GPR153,DLL3,TRAF3IP2,SRCAP,GFER,GNAO1,CACFD1,IL6R,ITIH2,KCNN1,MEF2C,NPTX1,SNTG1,LRP12,CNTLN,RAB3A,RAB3IL1,ZMAT4,RGS10,SUGCT,TCP11L1,EMID1,SBF1,MRAS,PPP1R9A,FRMPD1,WDTC1,UNC5B,IQSEC2,INKA2,TCF4,SPX,GPR161,KCNK12,XRCC4,SYNC,EPM2A,FAM13C" Drug 4222_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ASPHD1,PLA2G6,MRTFA,BIN1,ARRB2,PDE8B,ALDH4A1,ST3GAL5,CACNB2,CACNA2D2,LY86,ARMC8,AATK,CSF1R,CTNND2,MFAP3L,PLPPR4,EXOG,DTNA,COQ7,EPHA5,ETV1,TRMO,DENND2A,ZMYND11,KCNMB4,GNAS,SHISAL1,IL11RA,DIPK1A,LMO2,PACRG,MN1,NDP,CNOT4,SLC11A2,CLDN11,PAK3,PPARA,GON4L,PTCH1,LGR4,PAQR6,CSRNP3,IL17RB,DOCK10,FBXO11,ANKRD6,PPP4R3A,SLC11A1,SLN,LIMCH1,KDM4B,THSD1,PLCB1,IQCE,TRIM2,ARHGEF12,ATP13A2,THRA,NSD2,KCNAB1,EPM2A" Drug 6514_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ACTN2,AK2,SYT13,ANK1,SEMA7A,GAS7,PLA2G4C,N4BP2L1,ADAM15,SYNJ2,LDLRAD4,CFAP410,CA4,USP2,FOXN3,ZFYVE9,KIAA1549L,NECTIN3,NCOR2,RGS6,ARHGEF10,VCAN,HP1BP3,RCAN1,DTNA,EDNRA,HEYL,SEMA3D,EFNB3,MBNL2,PLXNC1,RCAN2,TUBB4A,FHL1,TPK1,PRELID3A,GLS,GNAS,LPAR4,GRIK2,HLF,KCNH2,MSI1,MSR1,CAMKV,PPARA,PPP5C,PROX1,PTX3,PBRM1,TMEM206,KCNIP1,SBF1,SCN2B,SLC1A7,CXXC4,PHLDB1,AJAP1,ARC,ZNF34,HEY1,XRCC4,SLC30A3" Drug 3123_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "SPARCL1,CDC42BPA,AQP4,AQP6,RASL11B,MPDZ,BMP7,CACNB2,CACNB4,CAMK2B,CAPN3,CHRM4,COL9A3,SH2B1,CRYM,ATRNL1,USP6NL,EDRF1,SNPH,DAPK3,TMCC2,DLG3,ELAVL4,RCAN2,LRRC23,LRRC17,MTSS1L,ANKMY1,CEND1,CACNG3,OLFM1,GPR153,INPP5K,CPLX2,ALDH1L1,RAPGEF4,GRIK5,ITIH2,AFDN,NTRK2,OMG,PDE1C,CEP41,RELN,RGS10,RGS12,TTLL7,TCP11L1,SEMA6D,ASIC4,PALLD,WDTC1,CDK19,RBM26,ATP10B,PLCB1,CRTC1,TJP1,ICAM5,TNS1,VSNL1,SYNC,PMEPA1" Drug 3704_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ASPHD1,ADD2,ADORA1,RASL11B,BAIAP3,HAP1,CAMK2B,FOXN3,B4GALT6,CHRNB2,FAM189A2,CNTFR,CREB5,HAPLN1,NCOR2,CSNK1E,SLITRK5,SPOCK2,RABGAP1L,CHRDL1,DMPK,DSCAM,DTNA,EDN1,SGK2,FGF1,SEPT9,PCDH17,IL6ST,KCNQ3,VWA5A,SMAD1,MAN2A2,MAPT,ADAM22,TAGLN3,NPPA,NPTX1,OPCML,PDPK1,MAPK10,PLPPR1,PTHLH,PTN,PTPRB,PTPRH,FAM184A,KIRREL1,DZIP1,SLC1A7,RBM34,TSNAXIP1,UNC5B,ACSBG1,KAZN,HIF3A,TK2,TMOD1,RPRM,VGF,REEP1,EVI5,PARP6" Drug 4604_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ALK,ASCL1,SLC4A4,N4BP2L1,KSR1,CACNA1G,CACNA2D1,CAMK2B,RAB26,CNTFR,CABP1,NRG2,VCAN,PDE4DIP,NOS1AP,MFAP3L,C2CD2L,PLPPR4,EDNRA,SGK2,HIPK3,EIF5,EN2,COQ7,EFS,ETV1,C1orf61,SIGLEC8,SYT17,GLS,GNAL,GNG4,GRIN1,ADAMTS8,PTPRT,KCNA2,KCNC1,LSAMP,MSR1,LYRM9,NTRK3,OPCML,P2RX7,RETREG1,POU3F2,PRPH,ENOX1,RIT2,NEK11,CSRNP3,NLGN1,ANKRD6,SLC1A6,SNAP25,ARHGAP26,ARC,TACR1,TMOD1,RPRM,VGF,VIPR2,MVB12B,GJC2" Drug 3188_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "AMPD3,KCNAB2,APOC1,ARHGDIG,CCDC181,ATP2B2,N4BP2L1,AZGP1,RGS9,BTRC,CALB1,HAP1,ARHGEF2,SLIT2,NMT2,HOMER3,CABP1,IFFO1,CTIF,DCT,JAKMIP2,ATN1,DYRK1A,TENM1,FGF12,FHL1,PDLIM5,GAD2,GPM6B,TDRKH,NR3C1,HLF,JAK2,KCNMA1,KCNN1,MAP4,MMP17,GIT1,SLCO1C1,CDK18,PFKFB2,PIK3CD,PLCD1,NECAB2,PPP5C,DCHS2,PBRM1,FBXO11,SLC1A2,SLC6A8,SLC11A1,SLC14A1,OGDHL,SNAP25,KDM4B,SPTAN1,INKA2,SYT5,ROBO3,EXOC7,SZT2,UGT8,GDPD5" Drug 3399_DN Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ARID1A,AK2,LTBP4,APBA2,FAM131A,PPP4R4,PLA2G4C,CDK13,PDE8B,NRP2,GYG2,LDLRAD4,SLC16A4,SEPT7,LHX2,STOML1,CRY2,CSF1,CSNK1E,NOS1AP,KIAA0586,CTIF,CDON,DMTN,CAMSAP1,SCARA3,C1orf61,AGAP2,GAB1,GABRA2,SRCAP,RND1,GRM7,IL6R,KHK,MAP4,MSI1,ADAM22,PALM,PDE1C,CDK14,RAB3IL1,ZDHHC14,ZFHX4,EMID1,ASAP3,FNDC3A,LIMCH1,SOX3,EMC1,TROVE2,EXOC7,TBCEL,SMG6,DMXL2,PSD3,OBSL1,CRTC1,TK2,TMOD1,FAM155A,SPHK2,MAP3K12" Drug 4475_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ASPHD1,ARID1A,ADD2,LTBP4,APBB2,DDX3Y,ADAM23,NRP2,KSR1,KCNAB3,ARHGAP22,NRXN3,STOML1,NCOR2,MICAL2,PLCH2,TOX,RIMS3,ATN1,DTNA,PIPOX,DLC1,SCARA3,C1orf61,AGAP2,FLT1,FOLR2,SORBS1,ERAP1,GJB1,GRK4,GRIA4,GRIK5,CACFD1,GRM1,PTGDR2,KITLG,MYL3,P2RY13,NELL2,NOS1,NPY,PCBP3,TREM2,PIK3CD,PLCB2,EPN1,KHDRBS2,SCN2B,CNKSR2,SLC1A7,SLC11A1,ZSWIM8,HECW1,ZNF423,NFASC,PHLDB1,TAC3,DOCK9,CHST8,VAV1,VAV2,VIPR2" Drug 4418_UP Ethionamide [536-33-4]; Up 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "DPF1,SYN3,ASIC1,AP2A2,PLA2G6,SEMA6A,LTBP4,BIN1,APAF1,KCNAB2,GAS7,DDO,DNAH17,RASL11B,BAIAP3,CALB2,HIP1R,RUNX1T1,SEPT7,CACNA2D2,TAOK2,TPP1,AKAP7,WHRN,NOS1AP,CYBB,RIMS3,SPOCK3,EDN1,EIF4G2,TNK2,ZNF589,FER,KIAA1109,ANKFY1,FYB1,GAD1,GLS,INPP5B,MEF2C,ADAM22,MYL3,ENPP2,PFKFB2,TNPO2,PTAFR,ENOX1,FBXW7,SH3BP2,ARHGEF40,LIMCH1,SNCA,HECW1,CDK19,POPDC3,HEY2,TNS1,TRPC1,DNALI1,ITM2C,MVB12B,FAM13C,PHTF2" Drug 2401_UP Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "ADORA1,MTUS1,C1QTNF1,C1QTNF3,TRMT9B,BCAS1,AQP4,ASPH,ZSCAN18,ALDH4A1,ATP2A2,ATP2B2,ATP2B3,CFAP410,LARGE1,COL9A2,CSNK1E,DCAF4,DOCK4,DBT,GSDME,DMPK,ATN1,DSCAM,FAM13A,EIF1,MTSS1L,TUBB4A,AFF2,GPR153,SIGLEC8,ATXN2L,ITGAM,ITIH2,KCND3,MDM4,SCAMP5,NOS1,NUMA1,OLR1,PDE1B,RC3H2,TNPO2,PPP5C,PRKCZ,MAPK8,KLK6,PTPRD,RGS3,GALNT10,MRAS,SH3BP2,DOCK10,EPN2,FAM214B,IZUMO4,AJAP1,TCF7L2,PSD3,TPM3,FLRT2,ZBTB38,PCBP4" Drug 4199_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.26E-09 4.54E-04 6.69E-07 7.61E-06 63 197 "RALGAPA1,NR0B1,C1QTNF3,AMPH,PPFIA4,PDXK,CADM3,MPDZ,LDLRAD4,SYNGR3,LARGE1,AKAP5,PDE4DIP,CNTNAP2,PYGO1,DBT,SV2B,CDON,DTNA,HIPK3,EFNB3,AASS,TNK2,ETV1,FGF1,FLT1,PDLIM5,GAB1,DISC1,ADAM28,TDRKH,KLF12,BACH2,VWA5A,MMP16,NDP,NTRK2,KCNK10,CAMKV,RETREG1,RC3H2,ELOVL2,PTPRG,RASGRF1,GAL3ST4,KCNIP1,SUPT20H,NTNG1,PKNOX2,SHANK2,LIMCH1,KIF13A,CAND2,BEX1,PBLD,TBCEL,RPGRIP1L,DOCK9,PHF24,PCDHA5,TPM1,LAT2,NSD2" Drug CID000104751 BAPTA Stitch 9.36E-09 4.59E-04 6.76E-07 7.69E-06 91 324 "PLA2G6,PHF12,ARHGDIA,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BID,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALB1,CALB2,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,P2RX6,LRBA,CRLF1,CHRM1,CHRNA4,MYL6B,CNR1,SACS,EDN1,EDNRA,EIF4G2,FABP7,PTK2B,PPP1R1B,CAMKK2,ATP2C1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,KCNMB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR5A,MYLK2,IGF1,KCNMA1,MYL3,NOS1,P2RX7,P2RY1,PLCB2,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,RYR1,RYR3,MAPK12,FNDC3A,SLC6A1,SLC6A11,PLCB1,CABIN1,TRPC1,TRPC3,TRPM2,NTSR2,PLD4,NUP214" Drug 4279_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.98E-09 4.89E-04 7.18E-07 8.17E-06 62 193 "APBB2,CDC14B,ASPH,CCNT1,SRSF11,CHM,CLCN3,ABI3BP,CREB5,CSF1,SMG7,AK5,NR1D2,EGFR,MBNL2,ELAVL2,EPHA5,SEMA4D,PDLIM5,AHCYL1,SPIN1,POLL,BACH2,AGFG1,IL6ST,JAK2,KCNMA1,MMP16,LYRM9,NF1,CNOT4,SLC11A2,NTRK2,NUMA1,SSH1,RETREG1,STRN3,MED1,ACSS3,ATG16L1,SLC25A36,KIRREL1,ATXN7,SEC14L1,PPP1R9A,ASAP3,CCDC88A,KDM4B,WDTC1,SPTAN1,THSD1,ASTN2,TBL1X,TCF7L2,DICER1,TRIO,USP1,SF1,WNK1,SNX27,KCNAB1,KAT6A" Drug 3693_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.98E-09 4.89E-04 7.18E-07 8.17E-06 62 193 "PLA2G6,APBB1,KCNAB2,APP,CDC14B,CDK13,NCOA1,RASL11B,KIF1A,SYNJ1,CAMK2B,FOXN3,CHN2,B4GALT6,TAOK2,PLAA,IQCK,SH2B1,CREB5,PPP6R2,DAPK3,DMPK,CDON,MBNL2,PLXNC1,STX2,FGFR1,CSPG5,OGA,GAD2,SRCAP,HTATSF1,GPM6B,SPACA9,KLF12,ELOVL5,HNMT,HSD17B1,ITIH2,KIFC3,MAN2A2,MAPT,NPR2,ODF2,PCDH9,SERPINI1,PIK3R1,PTN,PTPRB,RAD52,RGS12,NEK11,MRAS,SLN,DOK5,LHPP,ARC,RPGRIP1L,TNS1,AMACR,RPRM,WNK1" Drug CID000004680 papaverine Stitch 1.05E-08 5.12E-04 7.51E-07 8.55E-06 58 176 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,AGT,PDE8B,ALDH7A1,DST,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,CACNA2D2,PLCXD3,EDN1,CACNG7,ENPP6,CACNG2,INPP5K,PLCD4,GUCY1A2,GUCY1B1,HBA1,KCNH2,NOS1,NPR2,ODF2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PKD1,PLCB2,PLCD1,GDPD2,RYR1,RYR3,SMPD3,TET1,PEG10,ABCC8,PLCB1" Drug CID000131938 LY235959 Stitch 1.07E-08 5.24E-04 7.67E-07 8.72E-06 19 31 "CA4,FOXM1,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,FNDC3A,SLC1A2" Drug 2672_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.07E-08 5.26E-04 7.69E-07 8.75E-06 61 189 "C3orf14,MTUS1,APBB2,ARHGAP5,DNAH17,HIP1R,CDH10,CLGN,COL9A3,SIPA1L1,DZIP3,PPP1R16B,DOCK4,ZNF337,RIMS3,DNAJC6,MAGI2,GSDME,PARD6A,MBNL2,LPAR6,SRPK3,EN2,EPS8,TLR7,TBC1D16,FER,PDLIM5,GABRA4,ADAM28,GNAO1,STON1,PCLO,IFI16,KIF5C,MEF2C,NCAM1,PCDH9,SERPINI1,SLC25A23,LRRN3,MAPK7,SIDT1,EMID1,ZNF415,TNIK,CDK19,RGL1,STXBP1,PJA1,CAMSAP2,PSD3,HEY1,SEZ6L,TRO,TRPS1,SSBP2,SLC17A7,FZD3,PHTF2,JPH3" Drug CID000003541 AC1MBZ1C Stitch 1.13E-08 5.53E-04 7.88E-07 8.96E-06 104 387 "ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRB2,PLA2G6,PRX,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,CCK,CCKBR,KRIT1,ARHGEF1,LRBA,CHGB,CHRM1,PCYT1B,AKAP5,CREM,CSNK1E,CALY,MATR3,DMPK,DRD1,EDN1,EDNRA,EDNRB,CALCRL,FOXM1,CAMKK2,ATP2C1,CRCP,GNAS,GPER1,RAPGEF4,GRIA1,GRM8,HRH3,TNFAIP8L3,HSF2,MYLK2,KCNA4,KCNB1,KCNC2,KCND3,MITF,CD200,NOS1,NPY,NPPA,NPR2,PDCD2,PDE1C,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLEC,PRKACB,PKIA,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,PTHLH,PTH1R,RAP1GAP,MAPK12,SLC9A5,SLC12A2,SNAP25,PLCB1,SYT1,TJP1,VGF,VIPR2,VSNL1,SCG2,PLD4,CAMK1G" Drug 7437_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ARID1A,AK2,APBB2,PPFIA3,ARHGDIG,MARCH3,ADAM15,MPDZ,BMP7,SCAPER,SGCE,CFAP410,CA12,NECTIN3,ENTPD4,MICAL2,RIMS2,DCAF4,GIT2,DNAJC6,PARD6A,ATN1,TOM1,HIPK3,MBNL2,IRAK4,COQ7,VPS26C,TESK2,ZNF589,FHL1,PRELID3A,GABRA5,ERAP1,ALDH1L1,MALT1,GNG3,ARHGAP19,IL6ST,KCNF1,KITLG,NF1,SETD4,SLC25A23,PPARA,PRPH,RIPOR1,RAB3IL1,ATG16L1,NEK11,EMID1,WLS,SLC1A7,SCMH1,ARHGAP26,VAMP1,ANKRD12,WSCD1,MICAL1,LMF1,ZBTB14,MAP3K12,PHTF2" Drug 2716_UP Hecogenin [467-55-0]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "C1QTNF1,BEGAIN,APC,MARK4,ZSCAN18,BMP7,CACNA1I,BTRC,SCARB1,SYNGR3,CDO1,SLC24A2,NRG2,CRY2,NCAN,FAM169A,PPP1R16B,PHF14,EDRF1,RIPOR2,KIAA0513,DBT,KLHL3,SV2B,DUSP9,ELAVL3,HSD17B14,OLIG2,KCNMB2,FGFR1,FHL1,PDLIM5,GLYR1,KLF12,MGAT3,CD200,NF1,CNNM2,PTAFR,CCDC40,ENOX1,GAL3ST4,RFX3,PLPPR3,SYNDIG1,RYR1,SEMA6D,CPEB3,ST6GAL1,CNKSR2,EFHD1,TMCC1,DOK5,ZHX3,IZUMO4,SYT5,AHCYL2,TEX15,TMOD1,PRMT8,KCNE5,FLRT1,PLPPR2" Drug 2964_DN Tridihexethyl chloride; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "GRAMD1B,AP2A2,MTUS1,CDC42BPA,APC,ASPH,ADAM23,BCL7A,SYNJ2,SCAPER,CFAP410,CAST,ARHGEF1,CLGN,SOCS6,CHM,HOMER3,PDE4DIP,SLITRK5,PPP6R2,ZFYVE16,SPATA2,RUSC2,DTNA,ABI2,CD320,F8,FHL1,POMT1,CAMKK2,ERAP1,SRCAP,ADAM28,VWA5A,MAP4,SCAMP5,MX1,NEK1,NF1,OGG1,PDE4A,ENPP2,NLE1,PTPA,PTAFR,PTPRN2,CEP97,RAD52,ZCWPW1,ANKRD6,ARFGAP1,KDM4B,IZUMO4,SYT11,VAMP1,ARHGEF9,PJA1,TCF7L2,TNS1,RBFOX2,PLPPR2,EVI5,MARCH8" Drug 4980_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASIC1,AP2A2,AGT,NME5,BIN1,FAM131A,AQP4,ARRB1,SLC2A11,LDLRAD4,CAMK2G,CBFA2T2,ARHGAP33,CHN2,HOMER3,CSF1R,SEC14L5,DMPK,SIDT2,ELAVL2,RASGRP2,ERCC2,FGFR1,FHL1,SCARA3,OGA,GPM6B,NR3C1,GRM8,ICA1,KCNJ5,KIT,VWA5A,MAP2,MEF2C,NCAM1,NELL2,NNAT,NUMA1,KCNK10,RETREG1,CEP41,MAPK7,ZSCAN32,KCNIP1,FAM214B,KDM4B,WDTC1,RGL1,PHLDB1,VAMP1,OBSL1,CRTC1,DNAH7,TMOD1,PARD3,TRIO,FLRT2,WIPF1,ZBTB14,NDRG4,MKRN3,SEMA3B" Drug 3736_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADGRF5,C1QTNF3,MRTFA,TRMT9B,BIN1,CDC14B,ATP1A3,ATP2A2,ADGRB2,SYNGR3,PLEKHB1,STOML1,PICK1,MICAL2,SRGAP3,DMPK,DTNA,LRRC23,PRELID3A,OGA,GAB1,SIGLEC8,ALDH1L1,GLYR1,GPM6A,GRIK5,HSD17B1,ITGA7,KIT,LMO2,MPP2,MT1M,NPR2,NUMA1,GPR85,PFKFB2,PIK3R1,RETREG1,MAPK8,WDR25,PTAFR,PTCH1,PLPPR1,PTPRH,RNASEL,FOXRED2,BTBD7,SNCA,ZNF415,DOK5,SOX15,SPTAN1,COLGALT2,THSD1,MAPK8IP3,PCDHA5,AP4E1,TK2,DAAM2,PIK3R5,REEP1,PARP6,SCG2" Drug 5080_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "AGT,ALK,PPFIA4,KCNAB2,AQP4,ASCL1,CCDC181,CADM3,RGS11,RGS9,CACNG1,CACNA2D2,CHN2,CLTB,WHRN,CABP1,SUSD5,PDE4DIP,RIMS2,TOX,TRAPPC9,DRD1,EDNRB,EFNB3,MTSS1L,PIPOX,AFF2,CAMKK2,CGREF1,GFER,CACFD1,IRAK3,HPSE2,MAN2A2,ADAM11,MDFI,AFDN,ADAM22,MYT1,NEUROD1,P2RY1,PALM,TNPO2,LRRN3,PTPRB,PID1,RGR,RGS4,RGS12,KCTD17,FBXW7,FOXRED2,MRAS,DOCK10,PHLDB1,ACSBG1,SLC44A1,THRA,TNS1,UBE3A,VAV2,SEMA3B,MVB12B" Drug 4650_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ABAT,ACTN2,LTBP4,SYT13,DNAH17,PTCH2,B3GALT2,BMP7,CFAP410,KALRN,USP2,CDH10,LHX2,SULT4A1,FAM149A,CABP1,RGS6,BRINP1,C2CD2L,RABGAP1L,DRP2,ATN1,AASS,ELN,FABP7,NSG1,FYB1,TRAF3IP2,SIGLEC8,GPR75,GRIK3,SPACA9,IRAK3,IGF1,KCND3,KCNF1,KCNH1,ADAM22,MYH7,NRCAM,NTRK3,OLR1,P2RX7,PCSK5,ST8SIA5,SPATA6,POU3F2,CNNM2,RGS12,MYH14,SCN2B,SELL,CNKSR2,KANSL3,SNCA,HECW1,SMG6,THBS4,SLC44A1,TPM2,TRPC3,REEP1,CAMK1G" Drug 7471_UP Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ABR,ADORA1,PLA2G6,SYT13,SLC4A4,CACNA1D,FOXN3,ZFYVE9,PICK1,NCOR2,CSF1,PDE4DIP,NOS1AP,DAPK3,SIDT2,EGR3,MRNIP,ENO2,ACSL4,DLC1,GPR153,SYT17,C1QL1,RAB30,ADAMTS13,RNFT2,PADI2,TJAP1,JAK2,KCNH1,MAP4,AFF1,ADAM22,MYT1,PCDHGC3,PDE1C,PDE3B,PLXNB1,MBOAT7,LRRN3,CEP41,NKAIN1,KHDRBS2,MYH14,TCP11L1,RPS6KA2,IL17RB,SLC20A2,ZCCHC24,KDM4C,STX1A,ROBO3,ZNF34,KCTD2,CDK20,TRH,FAM155A,MICAL1,REEP1,TFIP11,SEMA3B,NAV2,PHTF2" Drug 2332_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "GRAMD1B,AP2A2,MRTFA,BMP7,CDK5R1,ARHGEF7,MTMR3,CA12,CACNG1,HIP1R,CBR1,CD38,CDC42,PLAA,RGS6,VCAN,PPP1R16B,RABGAP1L,SIDT2,ABI2,PLEKHA1,MTSS1L,CELF1,GABRA2,WASF3,MYOZ2,MSL3,LILRA2,GRIK5,ATXN2L,ELOVL5,KCNC1,VWA5A,MYO7A,ZNF862,MYT1,NUMA1,PENK,NLE1,NECAB2,PPP2R5C,RGS3,EMID1,SCN2B,GALNT10,MRAS,EPN2,SLC22A4,ZSWIM8,ZC3H13,SPTAN1,KIF1B,ZC4H2,SYT11,TCF4,TCF7L2,PSD3,RIMBP2,CDK20,PLPPR2,XRCC4,PCBP4,KAT6A" Drug 1532_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "RALGAPA1,ASIC1,DGKD,CDC14B,ARRB1,ALDH7A1,BAIAP3,BTRC,CACNG1,NEURL1,MYOM2,CACNA2D2,ZFYVE9,SLC24A2,NMT2,CNTN1,ENTPD4,NCOR1,CSF1,CNTNAP2,NOS1AP,SPOCK3,EFNB3,TENM1,MTSS1L,PTK2B,FOXG1,DCTN2,GNAL,GPD2,TDRKH,NR3C1,HAS2,KLF12,TJAP1,IL6R,INPP5B,KCNJ4,KHK,KPNA5,MAN2A2,MOBP,TAGLN3,PCDH9,SLC25A23,RAB3IL1,CEP97,SEC61A2,TMEM206,EMID1,FERMT1,WDTC1,ZBTB43,SYT5,POPDC3,WSCD1,CRTC1,TIAM1,TNR,PIK3R5,CHST5,ZFP37,EVI5" Drug 2165_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADD2,CNTNAP1,APAF1,EPB41L5,CDK10,MTMR2,CAMK2B,CAST,CD86,STOML1,PICK1,CREM,SH2B1,AATK,PPP6R2,NOS1AP,ZFYVE16,DBN1,SV2B,EEF1A2,MBNL2,SORBS3,EIF1,LRRC17,CEND1,BAIAP2,PDLIM5,CAMKK2,GALC,INPP5K,ALDH1L1,SRCAP,ADAM28,RND1,GPR19,GRIN1,GSN,PTGDR2,ATXN2L,ITIH2,KHK,MAP4,MBNL1,ZNF862,NUMA1,PDE4A,PRKCZ,WDR25,SYNDIG1,SBF1,STUM,SLC20A2,SPTB,SPART,CAMSAP2,TBCEL,KCTD2,ZMYND8,LMF1,VSNL1,SPHK2,ZBTB16,TIGD6" Drug 4414_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASIC1,LTBP4,AMPD3,ARHGDIG,ASPH,ADGRB3,GYG2,CFAP410,CALB2,CDH2,RAB33A,COL9A3,ST18,GSDME,DOCK2,ECM2,HEYL,EFNB3,EFS,SPEG,PIPOX,F5,ZNF589,OLFM1,C1orf61,AGAP2,GAD1,ATP8A2,NEU3,HPGDS,GLRB,RAPGEF1,ADAMTS13,GRIK5,GRIN1,IRF8,ITGA7,KIFC3,VWA5A,ADAM22,BCO1,MX1,OMG,PALM,PCDHGC3,CDK18,TNPO2,CEP41,PTX3,MARCH1,KHDRBS2,ZMAT4,CPEB3,SLC6A8,SLN,PEG10,AJAP1,POPDC3,LAT2,SLC17A7,ITM2C,MVB12B,DPF3" Drug 4265_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ABAT,SEMA6A,BBOX1,SYT13,PPP4R4,ASCL1,ATP2B2,SYNJ2,CACNA1G,KCNAB3,ADGRG1,NRXN3,DNAJB5,CNTFR,COL9A3,CSF1,PHYHIP,CTIF,C2CD2L,DRP2,EDN3,PIPOX,FAM198B,CORO2B,FGFR3,AFF2,EFCAB2,FYB1,GFER,HPGDS,TOX3,GPD1,PRUNE2,GRIK3,GRIN1,GRM8,ATXN2L,HTR2A,HTR5A,IL6R,KCNC1,KCNF1,MAN2A2,ADAM11,ADAM22,MYH7,NEFM,NF1,SLCO1C1,NPTX1,NTRK3,NUMA1,PCSK5,RASGRF1,FRMPD1,SOX2,INKA2,ACSBG1,SPX,RIMBP2,TRO,XRCC4,DNALI1" Drug 2402_UP Chenodiol [474-25-9]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "C1QTNF1,ANK1,BCAS1,ARRB2,CACNA1I,CAMK2B,NEURL1,NMT2,STOML1,CNTN1,DBT,DLG2,HS3ST2,DSCAM,EEF1A2,EFNA3,SORBS3,MRNIP,F3,AFF2,PDLIM5,INPP5K,POLL,PRUNE2,GPM6B,ICA1,KCNJ5,KHK,LAMA2,LSS,AFDN,SLCO1C1,NINJ2,SLC11A2,PDE4B,PIK3R1,EPN1,MAPK8,ZSCAN32,RGS3,SEMA6D,SBF1,SEC14L1,ASAP3,DOCK10,SLC9A5,ZNF415,ZCCHC24,ZSWIM8,ATP10B,TROVE2,SS18,DNMBP,WSCD1,OBSL1,TEX15,KCTD2,RBFOX2,TPM3,SSBP2,ZBTB14,ZNF225,UBE3B" Drug 2271_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ACTN2,AP2A2,LTBP4,AMPD3,GAS7,MARK4,CACNA1I,RHBDL1,CDH2,ASIC3,DNAJB5,SULT4A1,LY86,TCEAL2,CRMP1,CSF1,ARHGEF10,CDON,MBNL2,ING4,ELN,TUBB4A,SCARA3,DCTN2,EFCAB2,CAMKK2,ERAP1,ADAM28,CSDC2,HPGDS,GNAO1,GPER1,GRM1,GRM7,HTR2A,TJAP1,KCNJ5,MAOB,MAP2,MEF2C,MID1,MX1,CNOT4,NPY,OPCML,PCDH9,LRP12,PAQR6,ASIC4,ZFP2,FRMPD1,FNDC3A,SLC6A9,SLC11A1,COA1,DDN,MAPK8IP3,SLC19A3,CRTC1,UGT8,ZNF45,SPHK2,SLC17A7" Drug 3899_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "NDRG2,ADRA1B,LTBP4,AMPD3,CNTNAP1,ASPH,TAOK2,RAB33A,CNTN1,AKAP5,PLCH2,CYBB,CNIH3,PLPPR4,DLG2,SHANK1,ECM2,SNX29,EDNRA,FRY,C3orf18,KCNMB2,ERCC2,F5,PDLIM5,CAMKK2,GAD1,GPM6A,GRIK5,GUCY1A2,NXPH3,KCND3,KCNH2,LSS,MEF2C,MID1,ADAM22,NNAT,NOVA2,PALM,PLP1,PTAFR,ZSCAN32,RGS12,CARF,STUM,ST6GAL1,SLC6A9,SLC8A2,DOK5,IZUMO4,NCDN,MAPK8IP3,POPDC3,ATP11A,DOCK9,TEX15,DICER1,HEY2,TRPM2,FLRT2,LAT2,SENP7" Drug 4254_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADGRF5,SEMA6A,GAS7,BACH1,BMP7,CACNA1A,CACNB4,CACNG1,RUNX1T1,FOXN3,ASIC3,CHRNB2,COL9A3,ABCG1,CSF1,CSF1R,CNTNAP2,ERC2,PHF14,CTIF,MFAP3L,DTNA,ABCC9,USH1C,IRAK4,LRRC23,APC2,PTK2B,CORO2B,HBS1L,MYOZ2,NEU3,RND1,PRUNE2,GPER1,GRIK5,ITGA7,KCNC1,KCNJ3,KCNQ2,KIT,MYH6,NF1,NHLH1,NRCAM,EPN1,MAPK10,RAD52,PNMA8A,ASIC4,SNCA,SPP1,SPTB,LHPP,ACSBG1,ARHGEF9,ARC,TPM3,CADM1,ZNF24,SH3GLB2,NT5M,KAT6A" Drug 3710_UP Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ALAD,ALK,MRTFA,BEGAIN,ANK2,LGR5,AQP4,PDE8B,ATP2B2,BMP7,BAIAP3,KALRN,HAP1,CD86,ARHGEF2,CHGB,TAOK2,SULT4A1,CNTFR,MYRIP,CRYM,EDRF1,RIMS3,DAPK1,MFAP3L,ARNT2,HS3ST2,ST8SIA3,EDN3,APC2,CACNG2,AGAP2,FYB1,GAB1,SIGLEC8,ALDH1L1,GNAL,GNAO1,GPR17,IRAK3,IRF8,IGFBP1,ITIH2,KCNB1,KCNK2,CD200,ADAM22,CLDN11,P2RX7,PGAM2,PRODH,NKAIN1,RGS4,SEMA6D,RASA3,RPH3A,TMOD1,TRPC1,TUBB1,ZIC3,KCNAB1,FAM13C,NLRP3" Drug 4258_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "MTUS1,PDE8B,ST3GAL5,CBFA2T2,DNAJB5,RAB26,WHRN,CREM,PDE4DIP,CNTNAP2,PPP6R2,ARHGAP24,TBC1D5,CNIH3,KIAA0753,KLHL3,DYNC1I1,RGS17,COQ7,ETV1,ST3GAL6,TESK2,ZNF589,TRMO,SORBS1,GABRA2,POLL,PRRC2B,BACH2,HNMT,SHISAL1,DIPK1A,ITPKB,MX1,NDP,CNOT4,CLDN11,PAK3,PIK3R1,RETREG1,PLCD1,RC3H2,PPARA,GRAMD1C,PRPH,PTPRN2,TMEM231,ENOX1,RXRA,SUPT20H,ZFP30,TNIK,SAMSN1,IQCE,ARHGEF12,TEX15,ZNF34,SMUG1,HIRA,WIPF1,ZNF74,FZD3,PHTF2" Drug 5690_UP Droperidol [548-73-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "SYN3,ASIC1,MRTFA,BEGAIN,DOC2A,CDC42BPA,APBA2,AQP6,CCDC181,SLC4A4,PROM1,CACNG1,KALRN,RUNX1T1,CDH2,NRXN3,CLCN4,CNTFR,PDE4DIP,EGFR,ELAVL2,MRNIP,SCARA3,OGA,CHL1,GABRG2,SRCAP,RAB30,GLRB,TOX3,GRIK5,GRM8,SOX21,KLF12,SHISAL1,KCNC1,KCNK2,KHK,MDFI,CD200,NELL2,NOVA2,P2RY1,PDE1C,PFKFB2,PLCD1,PLXNB1,LRP12,RASGRF1,PRR5L,SYNDIG1,TMEM156,FRMPD1,SLA,KANSL3,SLN,MYH15,RIMS1,ZNF415,SAMSN1,MAPK8IP3,VAMP1,THRA" Drug 2108_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASIC1,SEMA6A,ALK,KCNAB2,APP,LGR5,CACNA1I,CAMK2B,CBFA2T2,SCARB1,CDH8,LARGE1,CHRNA4,ARHGAP22,CRY2,C2CD2L,LRRC23,GAB1,GPR162,GLYR1,TOX3,KCNMB4,GNAL,GNAO1,GPM6A,LPAR4,GRIA1,GRIN1,IGSF1,ITGA7,SMAD1,MDFI,GIT1,MT1M,NEUROD1,NF1,P2RY1,ENPP2,PPARA,LRRN3,PPP5C,PRPH,PTAFR,ZCWPW1,RGS10,SELL,MRAS,DOCK10,ZNF334,SLN,MYH15,SNAP25,WDTC1,ZHX3,SAMSN1,ADGRL3,THRA,VIPR2,WIPF1,NT5M,NUP214,NLRP3,GAN" Drug 5410_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "KIDINS220,PLA2G6,ALK,AQP6,CDC14B,ARHGDIG,ATM,ADAM23,MPDZ,BAIAP3,LDLRAD4,CA12,CACNA1D,CAMK2B,CBFA2T2,CLGN,ARHGAP22,NOS1AP,GSDME,CDON,DSCAM,AASS,SORBS3,FHL1,SIGLEC8,ALDH1L1,GUCY1A2,KLF12,KCNK2,LIG4,SMAD1,MAN2A2,MDFI,CD200,MSR1,NEUROD1,NNAT,NOS1,NOVA2,P2RY1,PDE3B,TMOD2,LRP12,PPP5C,PRKCB,MAPK8,PROX1,PTHLH,SHANK2,SLC22A4,SMARCD3,WDTC1,KIF21B,DOK5,COLGALT2,POPDC3,DOCK9,GPR161,ZNF34,TMOD1,PIK3R5,EVI5,PARP11" Drug 3727_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADGRF5,ANK3,PPFIA3,CDK13,ADGRB2,CACNA1A,CAST,LARGE1,FOXN3,LHX2,CNTNAP2,CTIF,RUSC2,AK5,DMPK,DTNA,ING4,DMTN,WAC,FGF1,FGFR1,PDLIM5,TRAF3IP2,B4GALNT1,SEPT9,HTATSF1,KCNMB4,GNG4,FERMT2,GPM6A,CACFD1,ELOVL5,IL6ST,KCNMA1,MBD1,NFIX,NPR2,CEP41,MAPK8,PTCH1,PLPPR1,FAM120C,RPS20,ZNF821,BTBD7,SLN,SNCA,WDTC1,TSNAXIP1,DOK5,IQSEC2,CEP68,MLC1,SMG6,DOCK9,TEX15,CHST8,TRPC1,VAV2,VIPR2,VLDLR,WNT7A,TIGD6" Drug 2267_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASPHD1,ADGRF5,LTBP4,TRMT9B,CDC42BPA,APC,MYOM1,CFLAR,BAIAP3,CAMK2B,RGN,KCNAB3,RAB33A,WHRN,VCAN,NOS1AP,SPOCK2,CTIF,SPOCK3,RABGAP1L,TMCC2,SHANK1,ATN1,HIPK3,EFNB3,MBNL2,VPS13B,ERCC2,APC2,FGFR1,DLL3,SRCAP,GLS,GNAL,ATF7,GRM8,TJAP1,ITGAM,ITIH2,KCNMA1,MEF2C,MID1,MOBP,NF1,KCNK10,LRP12,MINDY2,MAPK8,SNRK,PTAFR,RFX2,RPS6KA2,SYNDIG1,ASAP3,DOCK10,SOX10,IQSEC2,POPDC3,PCDHA5,DICER1,AMACR,TRPC1,MVB12B" Drug 3548_UP Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADORA2A,NME5,SEMA6A,ANK1,APC,SPTBN4,MARK4,ATP1A3,GYG2,SGCE,CACNA1D,CALB2,CHM,PLEKHB1,CNTFR,FAM149A,SLITRK5,PHF14,DBT,SV2B,SPOCK3,CDON,DYRK1A,EFNA3,CORO2B,ST3GAL6,ZNF589,SEMA4D,GABRA2,TMEM8B,INPP5K,GATM,RND1,GLS,GPD2,ATF7,GPER1,GSTM5,IRAK3,MARK1,MGAT3,MID1,LYRM9,NF1,LRP12,SAMD9,PTN,CRTAC1,RGS12,RPS6KA2,SEMA6D,ITSN1,PKNOX2,SNCA,SPTAN1,ROBO3,WSCD1,TCF4,TNS2,WNK1,SCG2,SEMA3B,KCNAB1" Drug 4486_UP Napelline [5008-52-6]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "AP2A2,SEMA7A,APAF1,PRX,PPP4R4,CDK13,BRINP2,ATM,NRP2,CACNA1I,CACNB2,CACNG1,CAMK2B,CHN2,CHRNB2,STOML1,RCHY1,CSF1,MICAL2,PLCH2,RIMS2,DMPK,EPHA5,IGSF6,APC2,ETV1,DLC1,PDLIM5,ATP8A2,RUNDC3A,RND1,GNG4,TDRKH,GRIK5,ATXN2L,ICA1,TJAP1,SCIN,ITGA7,CNOT4,NOVA2,KCNK10,PIK3CD,NLE1,EPN1,TNPO2,PRKAR1B,ZSCAN32,RPS20,TRIM46,SUPT20H,SLC6A11,RIMS1,TNIK,MLC1,SYT5,ATP11A,SMG6,CUX2,REEP1,SEMA3B,MVB12B,CAMK1G" Drug 2326_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASIC1,ADRA1D,ANK3,PPP4R4,ARHGAP5,ASPH,GYG2,BAIAP3,BTRC,CFAP410,CA4,CA12,RAB33A,SULT4A1,CRMP1,SIPA1L1,CTIF,HP1BP3,ATN1,RCAN1,EDNRB,FEM1B,EFNA3,EFS,ZNF589,KIAA1109,CAMSAP1,AFF2,GABRA2,ALDH1L1,POLL,GRIK5,GRM1,GSN,TJAP1,VWA5A,MAP4,MIA2,MOBP,NF1,GPR85,PFKFB2,PPP2R2B,MAPK7,MAPK8,ELOVL2,RAD52,ZDHHC14,EMID1,SBF1,FRMPD1,PREX2,FAM214B,WDTC1,SYN2,ROBO3,SZT2,DOCK9,CABIN1,PIK3R5,FLRT2,XRCC4,GDPD5" Drug 6496_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "KLRC4,NME5,C1QTNF1,MRTFA,MARK4,CFAP410,CACNA2D1,CAMK2B,DGKI,GPR37L1,HOMER3,CNTFR,ENTPD4,VCAN,NOS1AP,MAML1,SPOCK2,HP1BP3,RUSC2,SRGAP3,RCAN1,DTNA,EDNRA,EGR3,PLXNC1,ERCC2,FABP7,HPCAL4,ANKFY1,SRCAP,TDRKH,SOX21,ITGAM,KCNB1,KCNN2,LSS,MAN2A2,MBD1,ADAM22,NEUROD1,CNOT4,RETREG1,NLE1,PPP5C,PRPH,RELN,SAMD9,ATG16L1,SYNDIG1,PREX2,PKNOX2,SORCS3,SNCA,UNC5B,PEG10,NPAS3,WSCD1,TRIM2,HIF3A,PARD3,LAT2,NSD2,XRCC4" Drug 6201_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "AP2A2,BIN1,OGT,PPFIA4,APBB2,SLC4A4,CDK5R2,CHI3L2,PICK1,CREM,CRYM,RIMS2,BRINP1,SPOCK3,CDON,DSCAM,OPTN,EFNB3,ELAVL2,MRNIP,LRRC17,STX2,TUBB4A,FGF1,FGFR1,C1orf61,AGAP2,NSG1,DLL3,B3GAT1,SIGLEC8,GATM,CSDC2,PCLO,GRIK1,CACFD1,GUCY1A2,KCNJ5,KCNN1,MSI1,ADAM22,MSR1,NCAM1,NOS1,PDE4D,POU3F2,MARCH1,CCDC40,RAD52,EMID1,SYNDIG1,RYR1,SLC1A7,SLC12A4,ZSWIM8,SPTAN1,PCDHGA1,CRB1,TK2,TUBB1,KCNAB1,FAM13C,PAK5" Drug 6726_UP Ioversol [87771-40-2]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ASPHD1,APC,CDC14B,PPP4R4,SLC4A4,FUBP1,BTRC,CAMK2A,SLC16A4,SCARB1,FOXN3,CLCN4,CABP1,VCAN,CTNND2,CYBB,INTS1,SRGAP3,AK5,DTNA,EDIL3,HIPK3,SORBS3,ELN,ETV1,FGF1,EFCAB2,OGA,GPR75,SHISAL1,IGSF1,IL12A,KCNJ5,LAMA2,LMO2,MAG,MMP16,NF1,NTRK2,P2RY1,PALM,GPR85,SPATA6,PPARA,MAPK10,CNNM2,PTPRG,ENOX1,RGS12,CCDC102B,PREX2,SNCA,CEP68,ZFR2,TCF4,PCDHGA10,PCDHA6,CABIN1,TRPC1,XRCC4,EMSY,DPF3,SENP7" Drug 6991_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-08 5.64E-04 7.88E-07 8.96E-06 63 198 "ADRA1D,SRPX,ARHGDIG,SLC2A11,MTMR9,CAMK2G,ARHGAP33,B4GALT6,COL4A5,ENTPD4,C2CD2L,SGSM2,DLG3,MED12,DUSP9,ENO2,LRRC23,ANKMY1,ZNF589,KIAA1109,FHL1,C1orf61,DPYSL4,ALDH1L1,GLYR1,ATXN2L,MAP4,MAPT,MIA2,MID1,ADAM22,NF1,OPCML,RETREG1,PLTP,PLXNB1,MAPK8,SNRK,KHDRBS2,GTDC1,ZFHX4,PAQR6,WLS,SAFB,SH3BP2,SLC22A4,ZKSCAN3,COA1,MAPKBP1,ZNF415,CDK19,ELOVL4,STX1A,VAMP1,WSCD1,TCF7L2,THRA,TMOD1,TPM1,TRPM2,SCG2,SEMA3B,PHTF2" Drug 2949_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.15E-08 5.65E-04 7.88E-07 8.96E-06 60 185 "ABHD6,KIDINS220,APBB2,APC,ST3GAL5,LDLRAD4,HIP1R,LHX2,CLCN3,RAB26,FEZ1,CSNK1E,PDE4DIP,GPRASP1,ZNF337,DNAJC6,KLHL3,GSDME,OPTN,EFNA3,SORBS3,TNK2,MRNIP,ETV1,FHL1,GATM,RAB40B,STON1,GRM7,PADI2,ITGA7,KIF5C,MEF2C,AFDN,ADAM22,NCAM1,NDUFA5,PCDH9,SERPINI1,GPSM2,SIDT1,RIPOR1,PPM1E,SLC1A3,EPN2,SLC9A5,PALLD,TNIK,SPTB,ELOVL4,RGL1,STXBP1,CAMSAP2,PDLIM2,TNS2,ATP13A2,RBFOX2,MAP3K12,GDPD5,FZD3" Drug 6193_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.23E-08 6.05E-04 8.40E-07 9.55E-06 59 181 "ADD3,NME5,APBB2,HIP1R,CHN2,LHX2,NMT2,RAB26,FEZ1,PDE4DIP,DZIP3,KIAA0513,RIMS3,DNAJC6,PARD6A,OPTN,EFNA3,MRNIP,ENO2,TBC1D16,FGFR1,BAIAP2,PCYOX1,RND1,RAB40B,GPR19,STON1,PCLO,KIF3A,DIPK1A,KHK,KIF5C,MYO6,NCAM1,PCDH9,SERPINE2,SERPINI1,RETREG1,PTPN13,TMEM255A,RPS20,SCG5,FAM102A,PPM1E,WDR47,PALLD,ZCCHC24,ZSWIM8,SPTAN1,ELOVL4,RGL1,STXBP1,SYT11,MTCL1,TRIM2,RPGRIP1L,HEY1,RBFOX2,SLC17A7" Drug 3688_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.23E-08 6.05E-04 8.40E-07 9.55E-06 59 181 "DPF1,ABAT,NME5,APP,CDC14B,ARNTL,ADGRB2,ST3GAL5,HIP1R,USP2,CLU,RAB26,ABCG1,FEZ1,PDE4DIP,CNTNAP2,CTH,NOS1AP,RIMS3,C2CD2L,DTNB,EFNA3,AASS,RGS17,TAOK3,BAIAP2,SORBS1,FYN,RND1,STON1,TPPP,GSN,GUCY1B1,DIPK1A,ITGA7,KCNH2,KIF5C,LIFR,MMP16,TAGLN3,PCDH9,SERPINI1,PIK3CD,RETREG1,RGS4,STUM,SH3GL3,SLC15A2,SNCB,TNIK,NFASC,ELOVL4,RGL1,SYT1,OBSL1,TNS1,DNAJC12,TRIM9,SLC17A7" Drug CID004133412 benzyloxyaspartate Stitch 1.24E-08 6.09E-04 8.40E-07 9.55E-06 21 37 "RHBDL1,DLG4,GFAP,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HMGB1,ITGAM,MAP2,PTCH1,SLC1A2,SLC1A3,SLC1A7,SLC6A1,SLC6A11" Drug 4371_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "LTBP4,BIN1,SEMA7A,DDO,ASCL1,ADAM23,RGS9,CAMK2B,CCKBR,SLC16A4,SEPT7,CDH8,CDH18,ZFYVE9,FAM149A,AATK,ARHGEF10,CNTNAP2,RIMS2,INTS1,SPOCK2,DYRK1A,EFNA2,HSD17B14,EPHA5,KCNMB2,FABP7,TUBB4A,GAD2,GPER1,GRM7,KCNC1,KCNJ4,KCNMA1,IPO5,MGAT3,MMP17,MYT1,NF1,PCBP3,OGG1,PIK3CD,MTRF1L,MAPK7,PTPRO,KCTD17,KLHL11,RPS6KA2,SLC11A1,SNAP25,SNCA,KDM4B,ZNF423,STX1A,VAMP1,ATP11A,R3HDM1,HIRA,KCNK12,EMSY,NT5M,PHTF2" Drug 4662_DN Menadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "ALAD,EP400,APBB2,FAM131A,SHROOM2,CDK13,EIF4G3,KRIT1,NIPBL,ABI3BP,SLITRK5,RUBCN,DOCK4,DBT,KLHL3,SMG7,MAMLD1,FCF1,EFNA3,LPAR6,STX2,FGFR1,EML4,IFI16,IL11RA,DIPK1A,SCAMP5,CNOT4,NPR2,PAK3,PIK3R1,SNRK,PID1,GTDC1,DOCK10,NUBPL,WDR37,PDZD2,PEG10,TROVE2,EPB41L3,TTBK2,DIP2A,VAMP1,VPS13A,SYT1,FAM208A,TBL1X,TCF7L2,TMPO,TRIO,TRPC1,SSBP2,HIRA,ZBTB14,NDRG4,SYNC,NAV3,NAV2,MPPE1,FZD3,UBE3B" Drug 7399_UP Methotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "C1QTNF1,SYT13,AMH,APOC1,CDC14B,SLC4A4,FUBP1,CACNA1I,CACNA1A,REPS2,WHRN,SDC3,CTNND2,USP6NL,SPOCK3,EXOG,DRP2,SIDT2,EFNA3,IRAK4,TENM1,LRRC23,ANKMY1,TESK2,FGF13,FGFR1,BAIAP2,DPYSL4,FYB1,GAB1,GNAL,GNG3,GRIN1,PTGDR2,LMO2,LSS,MATN3,MT1M,NF1,CLDN11,PDE4D,PMP2,PROX1,ZSCAN2,RAB5B,RAP1GAP,ZCWPW1,ARHGEF10L,TRAPPC13,ATXN1,SCN2B,SLA,SLC20A2,RBM34,WDTC1,SPTAN1,PHLDB1,VAMP1,KLHL4,RPRM,KCNK12,PLSCR4" Drug 3811_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "TTYH1,ASIC1,KLRC4,LTBP4,APAF1,GAS7,GYG2,MYRF,CFAP410,CDO1,CHN2,B4GALT6,NRXN3,ZFYVE9,SLC24A2,CRY2,NCOR2,CTNND2,DAPK1,SMG7,ATN1,DSCAM,DYRK1A,EDIL3,ETV1,FABP7,NEU3,SRCAP,GPR17,RAPGEF4,GRIN1,WIF1,HSD17B1,IL6R,LMO1,VWA5A,KITLG,AFDN,NF1,P2RY1,SNTG1,PDE2A,PPP2R2B,ELOVL2,PTPRG,ZMAT4,KLHDC8A,SYNDIG1,ZNF821,CNKSR2,KANSL3,BTBD7,SOX10,NXT2,MAPK8IP3,MLC1,MCF2L,DMXL2,DOCK9,ZMYND8,SPHK2,PRDM10" Drug CID006426631 Rp-cAMPS Stitch 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRB2,ALDH7A1,CACNA1D,CACNA2D1,CACNB2,CALM1,KRIT1,SLC5A11,LRBA,CHRM1,SLC22A6,DRD1,CALCRL,CACNG2,ACTL6B,CAP2,CRCP,RAPGEF4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM8,GUCY1A2,GUCY1B1,HTR5A,IGF1,KCNJ5,KCNK3,MAG,NODAL,NPR2,OXTR,PDCD2,PDE2A,PDE3A,PDE3B,PRKACB,PKIA,PRKCB,PRKCG,MAPK3,PTHLH,PTH1R,WDTC1,ACTR6,VIPR2" Drug 4129_DN Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-08 6.10E-04 8.40E-07 9.55E-06 62 194 "NDRG2,ADORA2A,PLA2G6,MRTFA,AMH,EPB41L5,BRINP2,ATM,FUBP1,CFAP410,ASIC3,CHM,CNTNAP2,EDRF1,RIMS3,SMG7,EFNB3,MBNL2,ING4,ERCC2,ATP8A1,FGFR1,CAMSAP1,DISC1,RAB30,GLS,FERMT2,GPD2,NR3C1,GRM8,RASSF8,IL6ST,INPP5B,KCND3,KIT,MAP4,MAPT,MATK,NF1,NFYA,PLCD1,PLPPR1,PTPRO,TCP11L1,RPS6KA2,FNDC3A,CCDC88A,COA1,SNAP25,SNCA,ZC3H13,THSD1,PLCB1,TBCEL,SMG6,AP4E1,THRA,TMPO,PRDM2,SCG2,KAT6A,PHTF2" Drug CID006436102 NF T Stitch 1.34E-08 6.57E-04 9.04E-07 1.03E-05 61 190 "SERPINA3,ACHE,APBB1,APBB2,APLP1,APOC1,APP,ATP6V0A1,BCHE,CA4,RUNX1T1,CLU,CNR1,CX3CR1,DPYSL2,TUBD1,TUBB3,TUBB4A,FCGRT,FKTN,ARFGAP2,CELF1,GAP43,TUBA8,CYP46A1,GFAP,POLL,TUBA1C,TUBB2B,MAP2,MAPT,MBNL1,NEFM,NEFH,PLCD1,PTPA,KANSL1,PRKCG,MAPK3,MAPK8,MAPK9,RELN,RYR1,SNCB,SNCA,DDN,PLCB1,SYN1,ARC,SYN2,SYP,TTPA,TUBB2A,TUBB1,UBC,ZIC1,LRP8,TUBA1A,HPS4,FXR1,NETO1" Drug ctd:C086401 pentabromodiphenyl ether CTD 1.40E-08 6.85E-04 9.35E-07 1.06E-05 273 1270 "SDE2,ACHE,CLK4,ARID1A,SLC25A25,TMEM132B,CCDC85A,TMCC3,HHATL,ADRB2,BEND6,KLHL13,AGT,KCTD16,C1QTNF1,SPARCL1,C1QTNF4,SRPX,LCORL,GAS7,TNRC6C,SLC7A14,RGS20,PLA2G4C,ZSCAN18,ZBTB10,RASL11B,SLC2A11,ARHGEF7,FUBP1,CACNA1G,RAB29,CA12,CAMK2A,CANX,CH25H,CBS,KYAT1,CCNT1,CD86,DGKI,CDH2,DCLK1,CCPG1,TBRG4,ADGRG1,CHRM1,CHRM4,CHRNA4,CHRNB2,JAM2,NDST3,CNN3,CNTN1,WHRN,BTF3L4,AKAP5,SLC4A8,CRHBP,AKAP12,CRMP1,SLC32A1,ABCG1,CRYM,CS,TENM4,LRRC3B,ERC2,CTH,PHF19,RIMS3,MYEF2,CNIH3,AK5,GRIN3A,DNM1,CALN1,CPEB2,DOCK2,DPYSL2,DTNA,FEM1B,EEF1D,FSD1L,EFNA3,RBM12,FAM13A,GPR61,EGFR,MBNL2,EGR3,EIF4G2,RGS17,ENO2,RCAN2,ABCA8,ZNF585B,FABP7,TUBA1B,TUBB3,CORO2B,TOMM40L,FGF14,ATP5PD,FOXO3,FLNC,DCTN2,UFM1,USP21,TRIM16,SARAF,GABRA2,GAD1,AHCYL1,GAP43,MTHFD2,ZNF559,SRRM4,DNER,GATM,GFAP,GLUL,GPT2,GPD2,GPM6B,GPR22,TUBA1C,RAPGEF4,STMN2,GRIA1,ADAMTS8,GUCY1A1,GUCY1B1,HLF,HNRNPK,HP,SMAP1,IRF8,IGF1,KIAA1755,IL6R,DIPK1A,JAK2,KCNB1,L1CAM,LAMA2,STMN1,INSYN2,LMO2,MAP2,MAPT,MAT2A,AQP11,ADAM22,MX1,NEXMIF,NAP1L2,NASP,NCAM1,NCF2,NDP,NEFM,SLCO1C1,NFIA,ALDH1L2,NPTX1,NRGN,CLDN11,GPR137C,PCDH8,PDE1A,PDE3A,PENK,TMOD2,CYTL1,OLA1,ABCB1,SSH1,RETREG1,XRN1,PKM,PLP1,PCDH18,SMIM7,PDZRN4,PSAT1,SLC36A4,PRKCZ,MAPK3,FITM2,DIRAS2,PROX1,APTX,PTHLH,PXK,PTN,OCIAD1,PTPRO,C1orf54,SLC6A15,RGS4,SEC61A2,RPE65,ARMH4,RPS6KA2,MEG3,MAPK12,SARS,SBF1,CSRNP3,SCN2B,SCN4B,FNIP1,SCG5,KIF21A,FERMT1,SHMT2,SLA,RADIL,CCDC88A,CPEB4,SNCA,SPP1,KIF1B,ZBTB43,RBM26,C11orf87,CLSTN2,TTBK2,RGL1,SEPT3,JMJD6,SYP,TAC1,SYNE1,TEK,DNAH7,C18orf54,TGFBR3,FBXL16,THRA,TLL2,PARD3,KAT6B,TPD52,TPM1,TPM3,TUBB2A,LINC00645,CADM1,AMOT,UCHL1,SLAIN1,PITPNB,ZNF709,BCL2L13,VLDLR,KLC2,GUSBP1,PCDH20,ZNF708,ZNF24,FMN2,DPYSL5,LAMP5,PRDM2,SLC38A1,CSDE1,TUBA1A,HNRNPA3,RNF170,NHSL1,NETO1" Drug 1659_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.41E-08 6.89E-04 9.35E-07 1.06E-05 57 173 "ADD3,NME5,MARK4,ST3GAL5,BAIAP3,CLGN,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNB3,MBNL2,EXTL2,F3,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,TDRKH,STON1,RNFT2,KIF5C,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,MAPK8,PRPH,PTCH1,SH3GL3,PPM1E,WDR47,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,DNAJC12,ZNF45,REEP1,SLC17A7" Drug 2572_DN Ergocryptine-alpha [511-09-1]; Down 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "SYT13,APBB2,SEMA4G,PDE8B,ALDH4A1,SLC4A4,CACNA1I,HIP1R,REPS2,FAM149A,RABGAP1L,NR1D2,CDON,EDNRB,EEF1A2,CELSR3,PCOLCE2,ELN,DMTN,RASGRP2,ATP8A1,KAT8,FHL1,GABRA4,ZNF44,GAD2,SEPT9,WASF3,SRCAP,CRCP,GLS,MSL3,LILRA2,NCKAP1L,MID1,AFDN,MYO7A,NOS1,MAPK7,MASP1,LRRC49,PTAFR,RIPOR1,FAM184A,MRAS,SH3BP2,FAM102A,FRMPD1,CNKSR2,SLC1A7,IQSEC2,DDN,SS18,KAZN,DMXL2,TCF7L2,TNS2,CRTC1,CHST8,TMOD1,TPM1,LMF1,STMN4" Drug 4262_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ABAT,NDRG2,ADORA1,BBOX1,PPFIA4,AQP6,ASCL1,ATP2B2,B3GALT2,MYOM1,KSR1,KALRN,GPR37L1,NDST3,NRXN3,NRG2,CSF1,CNTNAP2,CX3CR1,CTIF,ABCC9,EDNRA,ELN,PIPOX,FGFR3,GFER,CSDC2,TOX3,GRIA2,GRIN1,ADAMTS6,IRAK3,HNMT,HTR5A,KCNH1,MGAT3,ADAM22,NF1,NTRK3,PDE4A,RETREG1,PDZRN4,SEPT4,PPP1R1A,DCHS2,PTPRN2,KHDRBS2,RYR1,SCN2B,SCN3A,ARHGEF40,SOX2,IZUMO4,CDK19,SYT5,LILRA4,TRO,LAT2,ZNF225,PRDM2,NT5M,NLRP3,GAN" Drug 5806_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "BIN1,APC,SLC4A4,NRP2,CFLAR,ST3GAL5,CAMK2B,RUNX1T1,CCK,B4GALT6,CNR1,COL9A2,MYRIP,CPS1,CRMP1,VCAN,PDE4DIP,ARHGAP24,DCAF8,KIAA0513,ARNT2,CDON,EPB41,ERBB2,FGFR1,SEMA4D,FLT1,TRMO,CGREF1,TBR1,GNG3,GNG4,GRM1,KLF12,KCND3,KCNMA1,MAN2A2,MGAT3,GIT1,NEUROD1,CNOT4,PHKG1,PPP2R2B,WDR25,MYH14,PNMA8A,GSTCD,EMID1,FNDC3A,ELMO2,TMCC1,SOX2,CLASP2,SYT11,PHF24,THRA,RIMBP2,TPM1,TRIO,VIPR2,WIPF1,REEP1,MAP3K12" Drug 4188_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "TTYH1,SEMA6A,CADM3,ADGRB3,RGS9,PROM1,BMP7,CACNA2D1,CCK,CCKBR,SLC16A4,NEURL1,DLGAP1,CRLF1,ABCG2,FAM149A,DBT,NTM,ARNT2,DSCAM,EDN3,ELN,ERBB4,CACNG2,AFF2,NSG1,GAB1,GABRA2,GAP43,ERAP1,ADAM28,GLI2,GNAL,PTGDR2,HPSE2,ICA1,ADAM22,OPRL1,PDE4B,MTRF1L,PMP2,PTPRG,RASGRF1,RFX2,RTN1,PKNOX2,BTBD7,SORCS3,SNCA,KIF21B,LMO3,ACSBG1,SYT11,SYP,PCDHGB6,PHF24,THRA,TLR4,SEZ6L,TRPC3,ZMYND8,EVI5,EPM2A" Drug 5094_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "NDRG2,SLC12A5,EPB41L5,APOC1,ASCL1,PDE8B,DNAH17,N4BP2L1,NRP2,FOXN3,RAB33A,TMEM59L,IPCEF1,CTNND2,SPOCK2,C2CD2L,TOM1,HIPK3,AASS,COQ7,KCNMB2,NRN1,FGFR1,SORBS1,DISC1,SEPT9,GPM6B,LPAR4,GRIK5,BACH2,ICA1,TJAP1,AFF1,NEUROD1,CNOT4,PDE4D,PFKFB4,PTPRN2,TMEM231,FAT4,TMEM206,RPS6KA2,PAQR6,RYR1,FOXRED2,SCN3A,CPEB3,ST6GAL1,SLC2A5,SOX10,KDM4C,ZBTB43,DDN,LMO3,OBSL1,TMEM121,SEZ6L,ZMYND8,WNK1,PRDM2,FAM13C,ST7,GAN" Drug 3609_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "MRTFA,GAS7,MARK4,BMPR1B,GYG2,CAMK2B,CDH18,ABI3BP,CPS1,CSF1,GREB1,RIMS3,MAML1,DBT,ELMO1,PARD6A,SRGAP3,HS3ST2,TRAPPC9,DTNB,EDN1,CALCRL,EN2,KIAA1109,NSG1,GAD2,GFAP,GFER,GPER1,GRM1,KLF12,INPP5B,KCNN1,KHK,VWA5A,MAN2A2,TAGLN3,DDX25,ZNF862,PCBP3,OGG1,OPCML,PACSIN1,POU3F4,MAPK7,TMEM231,RAD52,CRTAC1,RYR1,SALL1,SLC30A10,SLA,TSNAXIP1,NPAS3,COLGALT2,ACSBG1,ROBO3,WSCD1,OBSL1,PDIA2,VSNL1,ETNPPL,SPHK2" Drug 4090_UP Myricetin [529-44-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ABAT,ADGRF5,APBB1,APC,CDK13,ATP2B2,KSR1,MTMR3,CACNA1G,CFAP410,CACNB4,CAMK2A,RUNX1T1,ENTPD2,CHGB,NRXN3,AKAP6,CABP1,COL9A3,CSF1R,LRIG1,DRP2,DSCAM,HEYL,EFNB3,SRPK3,FAM198B,SIGLEC8,ADAM28,GRM8,GUCY1A2,HPSE2,KCND3,KCNJ3,LSAMP,MAG,MMP16,NNAT,ENPP2,ABCB1,CCDC40,RNASEL,EMID1,KCNIP1,SCN2B,FRMPD1,ASAP3,ST8SIA1,PKNOX2,SLCO1A2,SORCS3,SNCA,SOX2,DDN,MAPK8IP3,COBL,SYT5,HIF3A,KCNK12,MKRN3,DNALI1,SLC17A7,KCNAB1" Drug 6713_UP Monobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "MTUS1,NR0B1,PKP4,APC,AQP6,ATP1A3,ATP2B2,ADAM23,CACNA1I,IL33,CA12,CACNA1A,MTMR7,CHRNA4,RAB33A,CSF1,FEZ1,PDE4DIP,CTNND2,DAPK3,SPOCK2,CTIF,BRINP1,MFAP3L,SRGAP3,DMD,EDN3,PLXNC1,CALCRL,EPB41,NRN1,FAM198B,FOXG1,SEMA4D,NSG1,PCDH17,GPM6A,GRIK3,HTR5A,KCND3,VWA5A,MOBP,MYH3,NEUROD1,NF1,CNOT4,PC,ACSM5,CRTAC1,TCP11L1,EMID1,ZNF821,ZFP30,NTNG1,FBXO11,RPH3A,ARHGEF40,SOX2,SOX10,SPTB,PLSCR4,NLRP3,GAN" Drug 6819_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ADORA2A,AMPD3,AQP4,SEMA4G,ALDH7A1,SYNJ1,SCAPER,CA4,CLGN,ADGRG1,CHRNA4,KIAA1549L,FADS2,SULT4A1,LY86,NECTIN3,CPS1,PLCH2,VCAN,PDE4DIP,DCAF4,TMCC2,TRAPPC9,DTNB,HIPK3,HEYL,OPTN,EBI3,EGFR,SORBS3,ERCC2,ACSL4,AFF2,SORBS1,PCDH17,GNG3,NR3C1,GRM1,GRM2,GRM8,NXPH3,HNMT,INPP5B,KCNC1,KCNN2,KIFC3,MYO7A,CDK14,PTHLH,RGS12,MYH14,TCP11L1,FNDC3A,PKNOX2,NMNAT2,ARHGAP26,MAPK8IP3,CLASP1,AHCYL2,TMOD1,TPM3,KCNAB1,KAT6A" Drug 5787_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "CDC42BPA,MARCH3,BCL2L2,CDK5R1,SYNJ2,C5,ARHGEF2,SRSF11,SOCS6,RAB28,CPS1,CSF1R,TOX,GIT2,C2CD2L,FEM1B,SORBS3,IRAK4,TNK2,SPEG,F3,BAIAP2,B4GALNT1,SRCAP,PCDH17,RAB40B,GNG4,GPM6B,TJAP1,MAP4,MATN3,TM6SF1,SCAMP5,ZNF862,NACA,POU3F2,PPP5C,RALGDS,PAQR6,CSRNP3,ZNF821,ASAP3,FBXO11,ST6GAL1,FAM214B,CCDC88A,BTBD7,WDTC1,KDM4C,SPTAN1,RAP1GAP2,LHPP,THSD1,ELOVL4,SUPT5H,SYT1,COBL,WSCD1,CHST8,MICAL1,ZBTB14,HPS4,UBE3B" Drug 6686_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "NR0B1,ADGRF5,DOC2A,ANK2,BCAS1,B3GALT2,BMPR1B,CACNA1I,LDLRAD4,KALRN,HIP1R,SLC16A4,DLGAP1,CACNA2D2,TAOK2,NRXN3,CLCN4,HAPLN1,NCOR2,ARHGEF10,MICAL2,MYEF2,EDN1,HEYL,ZNF549,GABRA3,GALR1,ALDH1L1,HPGDS,GPR75,TOX3,LPAR4,GRIN1,GRM1,GRM8,SOX21,ATXN2L,ITIH2,ITPKA,VWA5A,MDM4,KITLG,MOBP,P2RY13,NCAM1,NNAT,NOVA1,NTRK3,NECAB2,EMID1,ZFP30,ST6GAL1,CNKSR2,SLC6A9,SLC9A5,SOX10,INKA2,ACSBG1,COBL,TRPC1,KCNK12,REEP1,KCNAB1" Drug 5944_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "NLGN4X,AK2,ALCAM,LTBP4,ALK,CDC42BPA,GAS7,MARK4,ALDH4A1,CFLAR,BAIAP3,CA4,ASIC3,CHRNB2,RAB33A,CLCN4,COL9A3,NRG2,SH2B1,MICAL2,SOCS5,RIMS2,CTIF,CNIH3,EFNA3,EGFR,MTSS1L,CORO2B,GALC,DISC1,SRCAP,RUNDC3A,SYNPO,HNMT,ICA1,LMO2,SMAD1,MAPT,MEF2C,NFYA,NNAT,PLTP,CEP41,RNASEL,NEK11,FUZ,CNKSR2,EPN2,WDTC1,HECW1,ARHGAP26,SPTAN1,PHLDB1,STX1A,TMEM121,GPR161,FAM155A,MICAL1,VSNL1,ITM2C,MVB12B,EPM2A,SMIM8" Drug 3636_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ALK,MRTFA,AMPD3,APOC1,ARSE,CDK13,BRINP2,GYG2,CACNA1G,CACNB2,CACNG1,DLGAP1,RCBTB2,INTS1,CTIF,TMCC2,HS3ST2,TRAPPC9,CDON,SGK2,EN2,DLC1,KIAA1109,GPR153,CSPG5,HBS1L,ALDH1L1,RND1,GPER1,PCLO,GRM2,KLF12,SYNPO,KCND3,KCNJ5,MAOB,MOBP,MX1,NELL2,NF1,NPY,TREM2,CDK18,PILRA,MAPK7,PTCH1,ELOVL2,C1orf54,TTLL7,SYNDIG1,ASIC4,DOCK10,PKNOX2,SHANK2,PLCB1,SYN2,SPX,TRH,TRIO,TRO,TTPA,ZNF154,SLC30A3" Drug 3707_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "LTBP4,ANK1,RASL11B,KIF1A,PROM1,CACNA1I,CFAP410,CACNG1,CD86,ARHGAP33,NDST3,RAB33A,AKAP6,RIMS2,NOS1AP,FRMPD4,MAGI2,DTNA,ST8SIA3,EGFR,AASS,LRRC17,EPHB1,ETV1,EYA1,FABP7,ZIC4,DKK3,GABRA5,ERAP1,GPD2,GPR19,SOX21,PADI2,IGSF1,KCNJ5,MEF2C,ADAM22,NF1,PFKFB4,PLCB2,STRN3,PRKAR1B,PROX1,PTN,ACSS3,NLGN1,RPH3A,SLC1A7,SLC15A2,LMO3,SSTR1,ACSBG1,KAZN,CUX2,TIAM1,R3HDM1,TNS1,TPM3,PRMT8,CA14,FLRT2,LAT2" Drug 4648_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ASPHD1,ACTN2,SPARCL1,SYT13,ANK1,ASCL1,B3GALT2,KIF1A,ADAM23,ADGRB2,BMPR1B,KALRN,RUNX1T1,SLC16A4,CDH10,GPR37L1,CBARP,PCYT1B,CABP1,CRYBB1,CSF1,DSCAM,DTNA,DYRK1A,ABCC9,EDN3,CELSR3,RASGRP2,MTSS1L,ARMCX1,KIAA1109,FGF1,OLFM1,SIGLEC8,CSDC2,TOX3,SPACA9,ADAMTS8,HLF,ICA1,KCNA2,KCNH1,KCNMA1,LAMA2,LSAMP,ADAM11,MGAT3,MYH7,P2RX7,PPP1R1A,PRPH,PTPRB,RGR,ST6GAL1,SLC8A2,SNAP25,FAIM2,SYNE1,RALYL,TPM3,TRO,LAMP5,SEMA3B" Drug 6631_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ACHE,ADD1,FZD9,KIDINS220,AMPH,SEMA7A,APBB1,GAS7,CDK10,BMP7,KALRN,HAP1,CAST,FOXN3,TPP1,AKAP5,TCEAL2,ENTPD4,RGS6,SV2B,HIPK3,EFNA3,MBNL2,ING4,ELN,FGFR1,GATM,NEU3,PRUNE2,GRIK2,IGFBP1,ITPKA,KCNJ5,AFF1,MMP16,FXYD1,MTRF1L,SPATA6,LRRN3,PRKAR1B,PRPH,ELOVL2,PTPRD,TMEM231,RGS4,KCTD17,PNMA8A,SCN2A,IL17RB,ASAP3,SLA,PPP4R3A,TNIK,DOK5,PHLDB1,TCF4,ICAM5,CDK20,VAV2,ZNF24,WNK1,PRDM2,HRASLS" Drug 2732_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ALK,BEGAIN,PPFIA3,DNAH17,ALDH4A1,CADM3,ADGRB1,BMP7,SGCE,SCARB1,CDO1,CHN2,TAOK2,NMT2,PICK1,PCYT1B,RIMS3,EDNRA,PLXNC1,VPS13B,F5,KAT8,DOT1L,GAB1,GAD2,ATP8A2,INPP5K,GRM2,KIF3A,NXPH3,HRH3,DIPK1A,KHK,KIF5C,CNOT4,PDE4D,PGAM2,POU3F4,PPP5C,CEP41,CNNM2,PTPRN2,RGS12,MYH14,SYNDIG1,RPH3A,SHANK2,SP4,IZUMO4,CAND2,PHLDB1,SYNE2,PSD3,TEX15,ATP13A2,TJP1,TRPC1,FLRT1,VGF,LMF1,VSNL1,ZFP37,SLC17A7" Drug 4359_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "SYT13,SEMA7A,APOC1,ATP2B3,CACNB2,CAMK2B,HIP1R,CDH8,GPR37L1,B4GALT6,TAOK2,SLC22A6,QKI,SULT4A1,CNR1,WHRN,VCAN,RIMS3,HEPH,NTM,AASS,ELAVL3,ELN,RASGRP2,KCNMB2,ERBB2,SPEG,FHL1,FYB1,FYN,ARPP21,SRCAP,GPER1,GRIK2,NR3C1,GRM7,GUCY1B1,LRP1B,SLCO1C1,PCSK1,PCSK2,EPN1,PLP1,CEP41,MAPK7,RELN,PTPRO,RGS12,TTLL7,SLC30A10,SLC2A5,SLC8A1,SLC14A1,PEG10,PHLDB1,ABCC8,EXOC7,TNS1,UGT8,WIPF1,LAT2,SLC13A3,DPF3" Drug 5817_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ADCY6,BRAP,NLGN4X,PLA2G6,BIN1,CDC14B,SEMA4G,SLC4A4,ATP2B2,KIF1A,C5,ADGRG1,CHN2,NMT2,CREB5,HAPLN1,SUSD5,HDAC9,CDON,ST8SIA3,CELSR3,STX2,ETV1,KIAA1109,OGA,FYB1,GABRA5,TRAF3IP2,GLYR1,LPAR4,KCND3,KCNK1,MAP2,MAPT,GIT1,SLC11A2,ODF2,PC,NLE1,PLCD1,POLG,PPP5C,BEND5,MYH14,CCDC25,FBXW7,SBF1,ZNF821,NLGN1,SLC11A1,SLC14A1,ELMO2,FAIM2,TSNAXIP1,MAPK8IP3,ASTN2,TRIM2,TLR4,TPM1,WIPF1,ZNF24,MKRN3,TFIP11" Drug 4338_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.43E-08 7.00E-04 9.35E-07 1.06E-05 63 199 "ADORA3,KIDINS220,NR0B1,ALK,PPP4R4,DDX3Y,BMPR1B,DNAJB5,SULT4A1,SNCAIP,IPCEF1,CNTNAP2,CYBB,MYEF2,TENM1,REEP2,BAIAP2,FOXF2,PDLIM5,GAD2,RUNDC3A,RND1,GPR19,GRIK5,GRM2,GRM8,SOX21,IRF8,ITIH2,KCNB1,MAOB,NOVA2,NPTX2,NTRK2,PIK3R1,NECAB2,TNPO2,PPP2R2B,VPS13C,PTPRE,RAD52,RET,RLBP1,SLC1A6,FAM214B,PKNOX2,SLC15A2,CXXC4,ZSWIM8,SPP1,IQSEC2,NFASC,ATP10B,PLCB1,MCF2L,CRTC1,SLC44A1,SEZ6L,CA14,LAT2,SF1,NT5M,MVB12B" Drug 6891_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.44E-08 7.07E-04 9.43E-07 1.07E-05 60 186 "ABHD6,NME5,MARK4,BMP7,BAIAP3,CBFA2T2,CDH18,CLGN,WHRN,COL4A5,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,OPTN,EFNA3,EFNB3,STX2,F3,ACSL4,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KIF5C,MITF,NEK1,PDE4A,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,SH3GL3,CPEB3,ZNF365,WDR47,FAM214B,ZCCHC24,KIF21B,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,HEY1,R3HDM1,RUNDC3B,DNAJC12,SLC30A3,EVI5,SLC17A7" Drug 1012_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "ASIC1,AK2,AMT,APOC1,MARCH3,CAPRIN2,CFLAR,CA4,KYAT1,KRIT1,ZFYVE9,FAM189A2,SMARCAL1,LRIG1,ATRNL1,CTH,JAKMIP2,LYPD1,DMPK,CNNM1,SIDT2,IRAK4,ZNF589,FGFR1,RND1,COPS8,GPER1,GRB10,MUM1,ICA1,IGF1,KHK,KIF5C,MAPT,MIA2,MPP2,ADAM22,BCO1,LYRM9,CDK18,SLC25A23,PPP2R2B,PPP5C,MAPK8,RIPOR1,RALGDS,FAM184A,ROM1,RPS6KA2,ZNF821,ZFP30,ZSWIM8,ARHGAP26,POPDC3,TRIM2,ZNF34,CABIN1,DNAJC12,VAV1,WIPF1,FTSJ1,MAP3K12" Drug 6761_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "ASPHD1,ASIC2,SLC12A5,MTUS1,C1QTNF3,GAS7,DDO,CCDC181,N4BP2L1,BSN,IL33,CLDN10,CDC42,IFFO1,CRYBB1,FEZ1,VCAN,PHF14,ZBTB24,PLPPR4,SGSM2,ING4,FGFR1,FOXG1,ERAP1,GPM6B,GRIA4,GSTM5,ELOVL5,TM6SF1,ADAM22,LYRM9,NOVA2,NTRK2,P2RY1,PDGFRA,RETREG1,MAGEL2,POU6F1,PTPRN2,TMEM231,MARCH1,TMEM206,MCMBP,FBXO11,ANKRD6,ZHX3,EMC1,BEX1,IQSEC2,MAPK8IP3,ASTN2,TAL1,PCDHGA10,TMOD1,SEZ6L,TPM1,FLRT2,FLRT1,KCNAB1,EPM2A,JPH3" Drug 3942_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "ABHD6,NME5,LTBP4,KCNAB2,ARRB1,BCL2L2,SYNJ1,GYG2,CDC42,CLGN,B4GALT6,DNAJB5,CNTFR,ARMC8,NECTIN3,DZIP3,RIMS2,MFAP3L,EXOG,ATN1,DUSP9,EFNA3,EFNB3,CELSR3,ERBB2,VPS26C,ANKMY1,FGFR3,SYNCRIP,GALC,INPP5K,GLS,GNG3,CNTRL,ADAMTS13,NR3C1,INPP1,KCNH2,KCNN2,ADAM22,BCO1,LYRM9,LRP12,PRPH,PTHLH,RAB3IL1,RGS12,TCP11L1,SIRT2,PDZRN3,ZCCHC24,CDK19,ATP10B,TACC1,IQCE,PCDHA6,BEX4,RBFOX2,TRIO,ZBTB14,ZNF24,MARCH8" Drug 5576_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "ADD2,ADORA2A,C1QTNF1,ABCD2,APC,PRX,ATP2B2,AZGP1,LDLRAD4,CACNG1,USP2,WHRN,SNPH,SPOCK2,CTIF,GSDME,SV2A,DRD1,ATN1,SNX29,EDNRB,ING4,DMTN,CORO2B,FGF1,OGA,GNAS,PRUNE2,ADAMTS13,GRIK5,GRM7,ICA1,KCNJ5,MGAT3,MMP16,MYCN,P2RY13,SNTG1,PAX6,GPR85,PFKFB4,MTRF1L,PRKCB,MAPK7,SAMD9,PTAFR,RFX2,SYNDIG1,SCN8A,SNCA,HECW1,ZNF423,ZC3H13,SPTB,ACSBG1,SYT11,SYN2,SZT2,GPR161,TPM2,FLRT2,SLC17A7" Drug 4016_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "RALGAPA1,ABAT,AP2A2,ALK,ANK2,PPP4R4,RASL11B,SLC4A4,NRP2,CFLAR,SYNJ1,BTRC,LDB2,TPP1,HOMER3,AKAP5,TCEAL2,ENTPD4,CNTNAP2,RIMS3,EDIL3,EDNRA,HIPK3,FCF1,CELSR3,ING4,ERBB4,ETV1,NRN1,ZNF589,C1orf61,NEU3,STON1,ELOVL5,IGFBP1,ITGA7,KCNN1,NEUROD2,CNOT4,SETD4,PMP2,TNPO2,LRRN3,GON4L,ATG16L1,BEND5,STK32B,CPEB3,DZIP1,SLC4A3,OGDHL,ZBTB43,EXOC7,TMPO,R3HDM1,CDK20,TRIO,VGF,ZNF225,PRDM2,PHTF2,DPF3" Drug 2245_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "ACTN2,NDRG2,KIDINS220,LTBP4,AMPD3,BIN1,CDC42BPA,RGS20,PLA2G4C,MARK4,ASPH,CACNA1A,CBFA2T2,CDH10,CHRNB2,LHX2,WHRN,COL9A2,SH2B1,CSF1R,PDE4DIP,MFAP3L,CDON,EFNA3,EIF4G2,CAMSAP1,FHL1,GCNT2,POLL,GPER1,CNTRL,INPP5B,KCNF1,VWA5A,MSI1,ADAM22,NOS1,NTRK2,OPCML,CDK14,PRODH,PEX5,RAB3A,ZCWPW1,ARID4A,TRIM68,RGS12,TCP11L1,FOXRED2,SBF1,CNKSR2,ZCCHC24,EMC1,MAPK8IP3,WSCD1,SLC44A1,TMOD1,WIPF1,GDPD5,HPS4,KAT6A,NUP214" Drug 4696_UP Ofloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-08 7.58E-04 1.00E-06 1.14E-05 62 195 "DPF1,NME5,ALCAM,AMPD3,CDC42BPA,CDK13,BRINP2,SCAPER,CALB2,TAOK2,NRXN3,CREM,CSF1,CNTNAP2,ARHGAP24,ATN1,EDN3,EDNRA,EFNB3,NRN1,KIAA1109,FGFR1,B3GAT1,GLYR1,TOX3,GPM6B,GPER1,GRB10,GSTM5,HLF,INPP5B,KCNC1,IPO5,MID1,MYCN,PDE4B,SLC25A23,PMP2,RAB3IL1,RAD52,RORB,ZFP2,ASAP3,CCDC88A,ZKSCAN3,ZNF415,RBM26,PLCB1,KAZN,WSCD1,DMXL2,TCF7L2,PCDHA5,TGFBR3,THRA,CHST5,TTPA,VAV2,WIPF1,WNK1,PRDM2,SLC17A7" Drug CID000023926 lanthanum Stitch 1.66E-08 8.13E-04 1.07E-06 1.22E-05 48 136 "ADCY2,ADCY5,ADCY6,ADCY8,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,KRIT1,AIFM1,ENTPD2,CACNA2D2,SLC24A2,CABP1,ABI1,CACNG7,CACNG3,CACNG2,PTK2B,ATP2C1,MAP4K5,KCNA1,KCND1,PKD1,MAPK3,MAPK4,MAPK7,GSTCD,RYR1,RYR3,RIMS1,TPCN2,TJP1,TRPC1,TRPC3,NUP214" Drug 2137_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.67E-08 8.19E-04 1.08E-06 1.23E-05 61 191 "MTUS1,BIN1,APBB2,ST3GAL5,SGCE,BTRC,HIP1R,LHX2,DNAJB5,RAB26,ABCG1,PDE4DIP,DOCK4,RIMS3,DNAJC6,SV2A,MAMLD1,MBNL2,ENO2,ETV1,BAIAP2,NBEA,ADAM28,PCDH17,GPR19,STON1,PADI2,TJAP1,DIPK1A,ITGA7,KIF5C,MEF2C,ZNF862,NCAM1,NRGN,NUMA1,PCDH9,PCSK5,SERPINI1,PLCD1,PTPN13,RIPOR1,TMEM255A,ROGDI,CCDC92,ANKRD6,SLC1A3,PALLD,ZCCHC24,SPTAN1,CEP68,RGL1,STXBP1,CAMSAP2,PSD3,OBSL1,ATP13A2,ICAM5,CLIP2,KLC2,MAP3K12" Drug 3975_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.67E-08 8.19E-04 1.08E-06 1.23E-05 61 191 "C1QTNF3,DOC2A,AMPD3,APC,ASPH,ALDH7A1,GYG2,CACNA1D,SLC16A4,CLTB,SLC4A8,CRMP1,CSF1,ARHGEF4,MAML1,DRD1,ATN1,EDN1,HIPK3,EFNB3,VPS13B,CEND1,F5,FECH,FGFR1,FHL1,AGAP2,CGREF1,GPR153,DLL3,SRCAP,TXNL4A,RAB30,GPR37,GRIK5,ITIH2,ITPKB,KCNJ5,KCNMA1,KCNQ3,KIT,SMAD1,KITLG,NF1,CNOT4,P2RY1,PCDH9,CEP41,PRKCB,MAPK7,SEMA6D,RPH3A,SHANK2,SLN,UHRF1BP1L,TSPYL2,DICER1,HIRA,RPRM,ZIC3,SENP7" Drug CID000120739 G 3012 Stitch 1.70E-08 8.31E-04 1.09E-06 1.24E-05 47 132 "KCNH8,UNC5A,SEMA6A,LRRC4C,SEMA4G,CHRD,NCOA1,AZGP1,SLIT2,PICK1,DCC,EFNA2,EFNA3,EFNB3,PTK2B,SEMA6C,SEMA4D,FYN,GAD1,NTNG2,FERMT2,HMGB1,L1CAM,LAMA2,MATK,NCAM2,NKX2-2,PLXNB1,RELN,PTK2,ROBO1,ROBO2,NTNG1,FNDC3A,SLA,SLC14A1,SLIT1,UNC5B,BEX1,SEMA4A,ROBO3,UNC5D,CNTN2,TRIO,RGMA,SEMA3B,RTN4" Drug CID000003878 lamotrigine Stitch 1.74E-08 8.52E-04 1.12E-06 1.27E-05 43 116 "ABAT,ASIC1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,ASIC3,CACNG7,CACNG3,CACNG2,GABRA1,LOXL3,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3,PTPN5,KCNH2,STMN1,MEST,ABCB1,PKD1,PTCH1,RYR1,RYR3,SCN2A,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TPCN2" Drug 2224_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "MRTFA,BIN1,FAM131A,ALDH7A1,N4BP2L1,ADAM23,ADGRB2,LDLRAD4,BTRC,CACNA2D1,CAMK2B,RHBDL1,CDH2,ASIC3,CHM,QKI,WHRN,ABI3BP,RCHY1,SNCAIP,VCAN,SPOCK2,HP1BP3,HIPK3,MBNL2,KCNMB2,SPEG,DLC1,OLFM1,FGFR3,FHL1,HPCAL4,HPGDS,GNAO1,GNG3,GPM6A,STON1,HTR5A,C2orf72,IL6ST,ITGAM,SMAD1,MAN2A2,MOBP,PCBP3,P2RY1,PACSIN1,TNPO2,PPARA,ELOVL2,ASAP3,ST6GAL1,PPP4R3A,CCDC88A,KIF13A,IZUMO4,ST5,MLC1,AP4E1,SEZ6L,WNK1,DNALI1,SLC17A7" Drug 3878_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "DPF1,NDRG2,ALCAM,BIN1,PPFIA3,PRX,PDE8B,ASPH,SLC2A11,CADM3,SCAPER,MTMR3,CAMK2B,SEPT7,CDH18,SOCS6,CRMP1,TENM4,RASSF2,SPOCK2,SHANK1,FER,FGF1,PDLIM5,GAB1,CSDC2,GLYR1,GNG3,GRIK5,KCNJ5,KCNN1,LMO1,SMAD1,KITLG,PAH,PDE1C,LRP12,MINDY2,LRRN3,MAPK7,GON4L,PTAFR,C1orf54,GAL3ST4,TTLL7,CARF,RPS6KA2,EMID1,ZFP2,RPH3A,EPN2,FAIM2,KDM4B,TSPYL2,TBCEL,CRTC1,DICER1,TMOD1,TNS1,LMF1,KCNK12,SLC17A7,KCNAB1" Drug 2728_UP Butacaine [149-16-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ABAT,NR0B1,PLA2G6,C1QTNF1,AMPH,APBA2,ARSE,ASCL1,ATP1A3,CADM3,ADGRB1,USP2,CDH2,LARGE1,CHN2,ZFYVE9,SV2B,CDON,RASGRP2,CACNG2,TUBB4A,DLC1,NSG1,TBR1,GAD2,HPGDS,GLRB,GRK4,GRIK2,HPSE2,TJAP1,KCNC1,MAPT,MBNL1,TAGLN3,NOS1,PDE1C,CAMKV,PURG,POU3F2,LRRN3,PPP5C,PKIA,MAPK7,PTH1R,RGS4,RGS12,MYH14,RPS20,SLC1A7,FAM214B,ZNF415,PALLD,IZUMO4,SYT5,ROBO3,CHST8,FLRT1,VAV2,LMF1,KLC2,SLC17A7,FAM13C" Drug 5445_UP Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ASIC2,ADD2,AP2A2,ADGRF5,CNTNAP1,APAF1,PPP4R4,RGS20,ASCL1,ATP1A3,SLC2A11,ADGRB3,CACNA1I,CACNA2D1,CD86,SYNGR3,ARHGEF2,ADGRG1,CHM,NCOR2,CSF1R,INTS1,USH1C,EDIL3,HIPK3,EGFR,IRAK4,ING4,ELN,IGSF6,EFS,FAM49B,PRELID3A,ZNF44,ERAP1,ALDH1L1,SRCAP,C1QL1,RND1,GPD1,SPACA9,GUCY1B1,C2orf72,KCND3,KCNJ16,KCNQ3,KIT,LMO1,MAP4,MAPT,MID1,ADAM22,MSR1,NF1,NOVA1,TRHDE,PTAFR,PLPPR1,RAD52,KCTD17,SLC9A5,ZHX3,KCNAB1" Drug 5502_UP Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ABHD6,ALK,CNTNAP1,APC,GAS7,APP,CDC14B,BRINP2,HAP1,INA,CBFA2T2,CDH18,SULT4A1,RCHY1,MED12,HIPK3,STX2,ERCC2,EZH1,ACSL4,FECH,FGF13,AGAP2,PRELID3A,GABRG2,GART,GPD2,PCLO,CNTRL,NR3C1,HNMT,SHISAL1,INPP5B,KCNK1,LIG4,AFF1,ADAM22,MYCN,NFYA,GPR85,PLP1,STRN3,PPP2R2B,PRKAR1B,PTCH1,RPS6KA2,SH3GL3,SLC2A5,PEX26,CAND2,TROVE2,NXT2,ASTN2,KAZN,SEMA4A,EXOC7,DMXL2,RPGRIP1L,TMOD1,LMF1,CLIP2,XRCC4,PCBP4" Drug 6181_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ACTN2,OGT,CNTNAP1,BCAS1,CDK10,ASTN1,SLC2A11,CADM3,MPDZ,BMP7,NGB,SLC16A4,ARHGEF10,NCAN,SMG7,SV2A,SEZ6L2,EFNA3,MRNIP,C3orf18,DMTN,TUBB4A,FGFR3,FHL1,GPR153,ADAM28,PCLO,GRIK2,GRIK5,IL1RAPL1,GUCY1A2,GUCY1B1,CELF3,PTGDR2,HPCA,KCNJ5,KCNK1,KCNN1,MSR1,TAGLN3,SAMD14,MYBPC1,NF1,PDE4D,PROX1,CNNM2,MARCH1,RPS20,ZNF821,SCG5,EPN2,SHANK2,PALLD,KDM4B,TSNAXIP1,PEG10,LHPP,ADGRL3,HIF3A,CRB1,TRIO,TRIM9,PRDM2" Drug 6038_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "AMPD3,AMT,CDC14B,MARK4,ADAM23,CACNB2,SNPH,RUSC2,NTM,ATN1,DTNB,HSD17B14,LRRC23,ERBB2,EFS,AFF2,FUT9,ZNF44,DISC1,ATP8A2,ALDH1L1,GFER,GNG3,GRM8,SOX21,HPSE2,ICA1,C2orf72,TJAP1,IL6ST,KCNN1,MOBP,MYT1,OMG,PCDH9,CDK14,LRRN3,MAPK7,MAPK10,PSD,SNRK,CNTLN,CCDC40,RASGRF1,KHDRBS2,RFX2,RGS12,DZIP1,PKNOX2,SLC11A1,ZSWIM8,COLGALT2,ST5,AJAP1,TACR1,CNTN2,TBCEL,ZEB1,SPX,TPM2,TRO,XRCC4,ZBTB16" Drug 5601_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "NDRG2,AGT,APC,CCDC181,KSR1,BAIAP3,CACNA1D,CAMK2B,CHN2,ZFYVE9,WHRN,CSF1R,GREB1,RASSF2,SPOCK2,DYRK1A,EGFR,EGR3,EFS,DCTN2,PDLIM5,GABRG2,PCLO,SPACA9,GRM8,GUCY1A2,ATXN2L,HPSE2,KCND3,KCNJ5,KCNN1,AFDN,MMP16,ADAM22,NCAM1,PDE1C,LRP12,DCHS2,ELOVL2,KLHDC8A,SYNDIG1,RYR1,CPEB3,SYBU,UNC5B,NPAS3,ATP10B,SAMSN1,ARC,KAZN,TAL1,ADGRL3,TCF4,ZEB1,HEY2,TRH,UCHL1,WIPF1,XRCC4,MKRN3,SCG2,KCNAB1,FAM13C" Drug 2265_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ADGRF5,PRX,CDK13,ASCL1,ATP1A2,ATP2B2,ADGRB1,CACNA1I,CFAP410,RUNX1T1,USP2,CDO1,DLGAP1,CNR1,CRMP1,CSF1,SPOCK2,EXOG,ELN,VPS13B,RASGRP2,NCALD,C1orf61,OGA,GAD1,SEPT9,GNAO1,GPM6A,IRAK3,KCNJ5,MATN3,MEF2C,MMP16,MSR1,MX1,MYCN,NNAT,NPPA,PDE4B,PFKFB2,GDPD2,PTCH1,CCDC40,GAL3ST4,RNASEL,ASAP3,FNDC3A,COA1,SOX2,SOX10,CDK19,COLGALT2,SSTR1,ACSBG1,JMJD6,ATP11A,EXOC7,HIF3A,TEX15,PIK3R5,TRPC1,MICAL1,KAT6A" Drug 4481_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ADRA1D,ALK,APAF1,AQP4,ATP1A3,CACNA1I,BTRC,CFAP410,CACNG1,CALB2,INA,CD86,CNTFR,COL9A3,CSF1,MICAL2,CTIF,BRINP1,MFAP3L,EXOG,DRP2,ATN1,SEMA3D,SIDT2,F5,DLC1,FGFR1,FAM49B,GAB1,ZNF44,KCNF1,MMP17,NCAM2,NELL2,CDK18,DUSP26,RETREG1,PLXNB1,ZSCAN2,NKAIN1,KCTD17,ROM1,ZNF671,MRAS,SH3BP2,FRMPD1,DZIP1,SLA,SLC1A7,SLC12A4,ZHX3,HECW1,SPTB,NPAS3,ASTN2,TACR1,MCF2L,KLHL4,DOCK9,ZFPM2,ZMYND8,REEP1,EPM2A" Drug 4242_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "PKP4,APAF1,APBB1,KCNAB2,APP,PPP4R4,ATP2B2,ATP6V0A1,MTMR3,CACNB2,HAP1,SLC22A6,SULT4A1,TCEAL2,CSF1,LRIG1,NCAN,PDE4DIP,MAML1,DCT,PARD6A,DNAH9,DTNA,IGSF6,PTK2B,DCTN2,ERGIC3,RND1,GRIK5,KLF12,KCND3,KCNN2,TM6SF1,NPTX1,OLR1,PDE3B,FXYD1,PNMA3,CEP41,CNNM2,PTPRB,RAD52,SH3TC2,C1orf54,GAL3ST4,ZMAT4,RNASEL,RAVER2,TCP11L1,RTN1,SELL,PKNOX2,OGDHL,TNIK,SPTB,AJAP1,MCF2L,TAL1,TBCEL,CRTC1,HIRA,KCNAB1,EPM2A" Drug 3689_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ADCY6,ADRA1D,NME5,ATP6V0A1,ADAM23,ADGRB2,CACNA1I,CACNG1,FOXN3,CHN2,LHX2,EPS15L1,NRXN1,LRIG1,SUSD5,PDE4DIP,CNTNAP2,PYGO1,RIMS3,DCT,ATN1,CDKL3,KAT8,KIAA1109,HPCAL4,C1orf61,SEMA4D,DCTN2,GAB1,POLL,GRK4,GRIN1,ITGA7,KCND1,KCNN1,MOBP,ADAM22,ZNF862,NRCAM,TREM2,SMIM7,LRRN3,MAPK7,SUSD4,RASGRF1,SALL1,CPEB3,NLGN1,NFASC,MAPK8IP3,DOCK9,OBSL1,CRTC1,PCDHA5,CRB1,TNFRSF1B,TMPRSS5,UCHL1,VAV1,VIPR2,SPHK2,PRDM2,EPM2A" Drug 5454_UP Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ADD2,BEGAIN,APAF1,PPP4R4,BAIAP3,CACNA2D1,CNTFR,COL9A3,CPS1,NCOR2,ATRNL1,SPOCK2,KLHL3,FEM1B,EFNB3,KCNMB2,ERCC2,CDHR1,OLFM1,CAMSAP1,CHL1,GATM,ADAM28,GFER,RUNDC3A,GLYR1,CACFD1,NR3C1,GRM1,ATXN2L,HLF,KCND3,VWA5A,MDFI,CD200,MYO7A,NF1,NNAT,PFKFB2,LRP12,PTAFR,RAD52,RASGRF1,TTLL7,KLHDC8A,ZNF821,FAM214B,CCDC88A,PDZD2,HECW1,BEX1,ARHGAP26,IQSEC2,ATP10B,MAPK8IP3,ARC,SYT5,ATP11A,DOCK9,R3HDM1,VAV2,WIPF1,KCNAB1" Drug 3765_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "RALGAPA1,ASIC2,ASIC1,C1QTNF3,SPARCL1,AQP4,CDC14B,CDK10,PTCH2,ASTN1,DDX3Y,BTK,LDLRAD4,KALRN,CAMK2B,CH25H,RUNX1T1,CHRNB2,CNTFR,RCHY1,RIMS2,BRINP1,DCT,HEPH,DLG4,EFNB3,ING4,ELAVL3,TNK2,RCAN2,FGFR1,SEMA4D,PDLIM5,GNG4,TPPP,GRIK5,ADAMTS8,GRM2,SOX21,IRF8,C2orf72,IGF1,AFDN,MMP16,MMP17,NEUROD1,SLCO1C1,NOVA2,NUMA1,SPATA6,ROM1,RYR1,MRAS,CNKSR2,SLA,IQSEC2,NFASC,ATP11A,ADGRL3,TMEM151B,PDIA2,EVI5,KCNAB1" Drug 3776_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-08 8.67E-04 1.12E-06 1.27E-05 63 200 "ADORA1,LTBP4,MRTFA,PKP4,APBB2,PDE8B,ASPH,RASL11B,MYOM1,SCAPER,GYG2,SEPT7,PCYT1B,CSF1R,RGS6,LRIG1,PLCH2,SEC14L5,SRGAP3,CDON,DTNA,EDNRA,SEMA3D,EFNA3,ING4,EXTL1,KAT8,FYB1,GATM,GFRA1,RND1,GPM6B,HNMT,C2orf72,KCNJ5,KCNMA1,MARK1,MMP16,MYT1,NPPA,NRCAM,NTRK3,NUMA1,PBX1,PURG,PTAFR,RAD52,RGR,EMID1,SEMA6D,STUM,SH3BP2,CPEB3,CNKSR2,SLC8A1,SLC15A2,SNCA,MAPK8IP3,HEY2,TNS1,WIPF1,MAP3K12,PHTF2" Drug 5884_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "NME5,MRTFA,ASCL1,BMP7,CACNA1G,MAP7,PLEKHB1,ZFYVE9,STOML1,QKI,LY86,RCHY1,PDE4DIP,GPRASP1,TBC1D5,GIT2,HEPH,MFAP3L,RUSC2,EXOG,EDN1,CNNM1,EIF4G2,HSD17B14,FAM198B,SCARA3,FYB1,GABRA2,POLL,GPR19,GRM1,LAMA2,NF1,SLCO1C1,NTRK2,NUCB1,PMP2,POU3F2,MAPK8,SAMD9,ENOX1,RGS10,KCTD17,NEK11,ASAP3,SLC1A7,PKNOX2,ZNF334,ELMO2,TMCC1,SPTAN1,DDN,NCDN,TACR1,EXOC7,PSD3,CABIN1,TNS1,XRCC4,REEP1,PRDM2,DPF3" Drug 5270_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "NDRG2,MRTFA,APBA2,APC,CDK10,ARHGDIG,PDE8B,ASPH,CFAP410,CDH8,ADGRG1,CPS1,PDE4DIP,GIT2,SMG7,EXOG,DNM1,DRD1,DTNA,HIPK3,MBNL2,EPB41L2,COQ7,PIPOX,EZH1,FGFR1,CAMSAP1,GALC,MALT1,GLS,GNG3,GPD2,STON1,GPER1,PCLO,CACFD1,NR3C1,GUCY1A2,IPO5,MAP4,ADAM22,ZNF862,SETD4,P2RY1,PENK,PLEC,MED1,PPP2R2B,MAPK8,RIPOR1,CARF,SH3BGR,CXXC4,SNCA,WDTC1,SOX2,ZCCHC24,ARC,AHCYL2,SLC44A1,ZKSCAN5,KLC2" Drug 3668_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ADGRF5,TRMT9B,GAS7,ATP6V0A1,ADAM23,BMP7,CACNA2D1,NEURL1,DCLK1,CHI3L2,ABCG2,HAPLN1,CTNND2,RIMS3,MYEF2,ECM2,IGSF6,KIAA1109,FGFR1,HPCAL4,TBR1,GAB1,GAP43,TMEM8B,ATP8A2,GFAP,HPGDS,GLI2,GRM8,IL12A,ITGA7,KCNJ5,ADAM22,NRCAM,PDE2A,PDE3B,PIK3CD,LRRN3,ZSCAN2,NKAIN1,CCDC40,RAD52,RGS7,RAVER2,STUM,SH3BP2,CNKSR2,BCAN,SLC15A2,ZHX3,UNC5B,ZC3H13,NFASC,AJAP1,PLCB1,SYT5,ATP11A,TAL1,TNS1,UCHL1,VIPR2,EPM2A" Drug 5533_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ADD2,PLA2G6,AMPH,BIN1,ANK2,GAS7,CDC14B,CCDC181,CNTN1,SH2B1,CSF1,FEZ1,MICAL2,C2CD2L,SNX29,EFNB3,ELAVL4,OLFM1,HBS1L,LYVE1,GLRB,POLL,GRB10,ATXN2L,KLF12,VSIG4,HNMT,ICA1,MAN2A2,MBD1,BCO1,MSR1,ZNF862,NF1,NFYA,NOVA2,NTRK2,PLPPR1,ELOVL2,PTPRD,PTPRZ1,ITSN1,CPEB3,AMBRA1,SMTN,ZKSCAN3,KIF13A,PSD3,CRTC1,TK2,TRPC1,TRPC3,HIRA,MICAL1,SPHK2,FTSJ1,SLC30A3,PRDM2,EVI5,SEMA3B,ADAMTSL3,DPF3" Drug 2687_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "NDRG2,KIDINS220,MTUS1,ALAD,BCAR3,CDC42BPA,PKP4,MPDZ,CACNA1A,QKI,ENTPD4,NCOR2,VCAN,CTH,DYRK1A,CNNM1,SIDT2,MRNIP,VPS26C,FGFR1,CAP2,INPP5K,RUNDC3A,GPD2,GPR22,GRB10,GRM1,MAP4K5,PADI2,ATXN2L,ITGA7,LIG4,VWA5A,MAP4,PDE4A,PIK3CD,PPARA,RAD52,TMEM206,CLIP1,ZFP30,FAM102A,NLGN1,EPN2,SLC6A8,SLC11A1,COA1,UNC5B,ARHGAP26,KANK1,ATP11A,WWC1,TCF7L2,AHCYL2,THBS4,THRA,TPM1,CDK20,TPM3,SSBP2,FLRT2,XRCC4" Drug 4574_DN Bicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ADRA1D,KIDINS220,MTUS1,NME5,MRTFA,KIF1A,CBFA2T2,ARHGAP33,RAB28,TPP1,DNAJB5,PICK1,AKAP7,ARMC8,CSF1,SLITRK5,TOX,CHRDL1,ING4,ELAVL3,MRNIP,BAIAP2,C1orf61,TRMO,PRELID3A,OGA,FYB1,FYN,SRCAP,USP19,GPM6B,GRIK2,SCIN,INPP5B,ITPKA,MDFI,MX1,CNOT4,FA2H,PRKAR1B,MAPK7,PROX1,CNNM2,CNTLN,PTCH1,ELOVL2,RPS6KA2,FNDC3A,BCAN,PEX26,SLC9A5,ELMO2,TNIK,ARHGAP26,ZBTB43,DOCK9,WNT7A,NDRG4,PRDM2,NT5M,EVI5,PHTF2" Drug 5015_DN Benzbromarone [3562-84-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "NME5,SRPX,ARHGDIG,ARRB1,SLC4A4,CANX,B4GALT6,ZFYVE9,CLCN3,STOML1,HOMER3,PDE4DIP,CNTNAP2,FAM169A,DCAF8,CDON,DSCAM,RCAN1,IRAK4,EN2,PLEKHO1,ENO2,STX2,ACSL4,ZNF589,FHL1,ANKFY1,PDLIM5,TXNL4A,RAB30,GNG3,INPP1,JAK2,KCNN2,ADAM22,ZNF862,NF1,RETREG1,LRP12,PTPRE,RAB3A,RAB3IL1,RGS12,RNASEL,FBXW7,SH3BP2,CPEB3,FNDC3A,SLC1A7,ZCCHC24,EMC1,ZBTB43,TCF7L2,TRIM2,PCDHA6,TRPC1,VGF,ZNF45,PRDM2,GDPD5,HPS4,KAT6A" Drug 874_UP (-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ADRA1D,ANK2,APBB2,CDC14B,ASPH,RGS9,GYG2,CAMK2A,TMEM257,COL9A3,RIMS2,MFAP3L,DSCAM,TOM1,DYRK1A,TSPAN5,EFNA3,EGFR,AASS,FYB1,DKK3,DISC1,SEPT9,NEU3,KCND3,KCNJ3,LIG4,NPTX1,NRGN,PCDH9,PIK3CD,SPATA6,MAPK7,PTHLH,PTPRB,RIPOR1,RAB3IL1,RASGRF1,KHDRBS2,RGS10,CARF,EMID1,ATXN7,ASAP3,NLGN1,ZNF365,PPP4R3A,KANSL3,SOX2,SPTAN1,MAPK8IP3,DIP2A,ATP11A,ANKRD12,SYNE1,TGFBR3,VGF,VIPR2,WIPF1,MAP3K12,NT5M,SCG2" Drug 5989_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "APP,ATP2B2,FUBP1,SCAPER,CD86,CDC42,CDH10,CACNA2D2,CHGB,CHM,CHN2,WHRN,DGKG,KLHL3,DMPK,C3orf18,COQ7,MTSS1L,ZNF391,ST3GAL6,GABRA5,GAP43,ATP8A2,GCNT2,GFER,GNAL,GPD2,WIF1,ATXN2L,TJAP1,KCND3,KCNJ5,KCNK2,KIF2A,LAMA2,MEF2C,NEUROD1,NOVA2,OPCML,PCDHGC3,PDE3B,DUSP26,SERPINI1,PLCD1,KCTD17,DCUN1D2,TCP11L1,WLS,ZNF821,SH3BP2,SH3GL3,PKNOX2,SLC6A9,RBM34,KDM4C,PLCB1,DOCK9,PSD3,TNFRSF1B,NTSR2,UBE3A,HRASLS" Drug 4772_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "DPF1,NDRG2,APC,CACNA1G,BAIAP3,LDLRAD4,CFAP410,CACNG1,LDB2,INA,ARHGEF2,CDH10,PLEKHB1,DNAJB5,CNTFR,CPS1,TENM4,OSBPL3,VCAN,PPP6R2,RIMS3,GIT2,DMPK,EFNA3,AASS,C3orf18,HSD17B14,F5,ZNF589,AFF2,FYN,GAB1,GAP43,GFER,GLRB,GRB10,KLF12,HLF,IRF8,KCND3,KCNJ4,KCNJ5,KCNMA1,KCNQ3,NEFM,OMG,CLDN11,PDE4A,RGS12,MYH14,TCP11L1,SH3BP2,TNIK,KDM4C,UNC5B,ARHGAP26,PLCB1,KAZN,HEY2,SLC30A3,KCNAB1,JPH3" Drug 4991_UP Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "AGT,MRTFA,ANK3,KCNAB2,APC,GAS7,PPP4R4,RGS20,PDE8B,ATP2B3,AZGP1,CFAP410,USP2,ARHGEF1,CDH10,CHN2,SULT4A1,WHRN,RUSC2,NTM,ATN1,EDNRA,EDNRB,VPS13B,EFS,FABP7,ST3GAL6,GAD1,SIGLEC8,ALDH1L1,SRCAP,POLL,GNAO1,GNAS,PRUNE2,PRDM5,ITGA7,KCND3,KCNH2,KCNQ3,MSI1,NEUROD1,NOS1,P2RY1,KCNK10,PCSK5,PLXNB1,KHDRBS2,CNKSR2,SYBU,RPH3A,SLC2A5,SLC6A8,COA1,ATP10B,TMEM121,TK2,CDK20,LMF1,WIPF1,MAP3K12,SEMA3B" Drug 2254_UP Etodolac [41340-25-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "SYN3,AMH,AMPD3,GAS7,CDK13,BAIAP3,CACNG1,KCNAB3,RCHY1,IFFO1,CPS1,CREM,NCOR2,VCAN,FAM169A,DAPK1,RUSC2,GSDME,HIPK3,CNNM1,HEYL,PTK2B,OGA,GAB1,ADAM28,GPR75,GLS,GPM6B,GRM1,KLF12,DHX35,C2orf72,ITGAM,ITIH2,KCNJ5,LMO1,MAP2,NEUROD1,CDIP1,LRP12,POU3F4,GON4L,PTCH1,PTPRN2,CCDC40,RAD52,C1orf54,RPS6KA2,RTN1,SCN2B,ZNF821,DOCK10,PKNOX2,COA1,SOX2,CDK19,MAPK8IP3,SMG6,TCF4,TMEM151B,SLC35G2,TUBB1" Drug 6363_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "DPF1,ADCY2,NME5,AMPD3,ANK1,APC,LGR5,ARRB1,PDE8B,SLC4A4,CBFA2T2,SULT4A1,CNR1,CNTN1,FAM149A,AATK,TENM4,CSF1R,CNTNAP2,ARHGAP24,RIMS3,DAPK3,EXOG,SNX29,EDN1,EDNRA,EFS,CORO2B,C1orf61,SORBS1,PDLIM5,KCNMB4,CELF3,NXPH3,PTGDR2,INPP5B,INSM1,MEF2C,SAMD14,MYBPC1,SNTG1,PIK3CD,STRN3,RELN,CNTLN,PTAFR,PTCH1,PTPRB,PTPRN2,FAM120C,DOCK10,RPH3A,SOX10,UNC5B,PEG10,SYT5,PSD3,TK2,CA14,UCHL1,UGT8,LAT2" Drug 4814_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ACTN2,EPB41L5,CDC14B,ARHGDIG,NOL4,ARHGEF2,CHN2,AKAP7,SNCAIP,CSF1R,RGS6,CHD5,CTH,RIMS2,MFAP3L,RUSC2,KBTBD11,C3orf18,EN2,LRRC23,FGF13,FGFR1,DKK3,GABRA2,HBS1L,MALT1,TDRKH,STMN2,GRM7,ATXN2L,VSIG4,HPSE2,IL11RA,KCNJ4,VWA5A,NNAT,NPTX1,NTRK2,SNX10,PLCD1,PPP5C,MAPK7,ZSCAN32,OGDHL,EMC1,SPP1,ZC3H13,ATP10B,THSD1,AJAP1,MLC1,PLCB1,ANKRD12,EXOC7,KIAA1107,TBCEL,PCDHA5,DAAM2,TRIO,AMOT,WIPF1,SLC30A3" Drug 1214_UP 2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ABHD6,ANK3,APC,MARK4,STX16,MPDZ,CA12,CACNG1,CHN2,PLEKHB1,CNOT8,CRY2,NCOR2,SLITRK5,RIMS3,PLEKHO1,PIPOX,FYN,GAD1,IQGAP2,SYT17,GLI2,FERMT2,STON1,DIDO1,GUCY1B1,ICA1,MMP16,ZNF862,NPR2,PBX1,PCDH9,PDGFRA,SPATA6,POLG,WDR25,PTPRB,GAL3ST4,RGS4,UEVLD,ZNF671,SBF1,SUPT20H,PEX26,EPN2,WDTC1,COLGALT2,SAMSN1,NCDN,ELOVL4,PHLDB1,SYT11,SYT1,COBL,ATP11A,SYNE1,GPR161,HEY1,UGT8,XRCC4,WNK1,PLSCR4" Drug 2871_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "RALGAPA1,FZD9,GAS7,MARK4,ATM,ADAM23,AZGP1,CACNA1A,ARHGAP33,ARHGEF6,WHRN,AKAP5,MICAL2,ST8SIA3,EFNB3,PLXNC1,C3orf18,ERCC2,SPEG,OLFM1,BAIAP2,AGAP2,SEMA4D,PDLIM5,FAM49B,SRCAP,GFER,NR3C1,GRM7,GUCY1A2,LMO1,BCO1,NF1,NNAT,NUMA1,PENK,SERPINE2,CDIP1,PBRM1,MYH14,EMID1,SELL,STUM,SH3BP2,FAM214B,LIMCH1,SPTB,SYN2,PCDHGA1,DOCK9,PSD3,TMEM121,GPR161,DAAM2,CHST5,ZMYND8,PDIA2,FLRT2,SLC30A3,EVI5,SSPN,DPF3" Drug 1479_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "ACTN2,PLA2G6,TRMT9B,BIN1,SLC4A4,ATP2B2,CFLAR,CDK5R1,SCAPER,NCOR2,AATK,CSF1,ATRNL1,CTNND2,RIPOR2,DAPK3,EGFR,PLXNC1,CALCRL,DMTN,TUBB4A,FGFR1,HPCAL4,FOXG1,IQCG,ERAP1,GLYR1,GRIK5,CACFD1,TJAP1,IL6R,KCNH2,KCNMA1,LMO2,AFDN,TAGLN3,SETD4,MAPK8,KCNIP1,NLGN1,SLC2A5,CXXC4,MAPKBP1,RBM34,ZCCHC24,EMC1,IQSEC2,POGZ,ASTN2,SYT5,TBCEL,WSCD1,CRTC1,TK2,PIK3R5,CDK20,VIPR2,MICAL1,SLC13A3,KCNK12,ZFP37,JPH3" Drug 7346_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "DPF1,ADRA1D,MRTFA,APBB2,RASL11B,ATM,ATP2A2,CFLAR,SCAPER,ARHGEF2,GPR37L1,B4GALT6,LHX2,LY86,BAG4,PDE4DIP,ARHGEF4,DOCK4,TBC1D5,ARMCX2,PARD6A,RABGAP1L,EXOG,TRAPPC9,EFNA3,EGFR,ING4,COQ7,ERCC2,FER,FGFR3,KHDRBS3,GPR153,SRCAP,RAB30,CACFD1,NR3C1,RASSF8,ATXN2L,KLF12,HSF2,INPP1,IPO5,MAP4,MAPT,NF1,SMIM7,LRP12,MAPK7,PRODH,PRPH,CNNM2,RIPOR1,GTDC1,RGR,ROBO1,SBF1,ZNF821,SYBU,EMC1,SIN3B,WNK1" Drug 5666_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-08 9.40E-04 1.18E-06 1.34E-05 62 196 "RALGAPA1,ARID1A,NDRG2,APOC1,CAST,KCNAB3,FOXN3,ASIC3,CREB5,HAPLN1,CRY2,SNPH,DCC,EFNA3,EGFR,ERCC2,DLC1,ZNF589,FGF1,FGFR1,FHL1,KHDRBS3,OGA,GABRA2,NEU3,GPM6B,TDRKH,LPAR4,GSN,TJAP1,KCNN1,MGAT3,CNOT4,NPTX1,PCSK2,STRN3,LRP12,POU3F2,MINDY2,PTAFR,RASA3,ST6GAL1,PREX2,SLC8A1,SLC11A1,ZNF415,BEX1,CDK19,RGL1,PHLDB1,SYT11,TRIM2,DICER1,HEY1,CHST5,LAT2,ZIC3,ZNF711,GDPD5,ADAMTS9,EPM2A,HRASLS" Drug 3400_DN 2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.08E-08 1.02E-03 1.27E-06 1.45E-05 61 192 "ARID1A,NME5,MRTFA,APBB2,APC,EPB41L5,APLP1,SCAPER,MTMR3,CFAP410,CACNA1D,USP2,ARHGAP33,ADGRG1,STOML1,SLC4A7,PHF14,RIMS3,GIT2,MFAP3L,DTNA,HIPK3,FEM1B,SIDT2,VPS13B,STX2,SPEG,FGFR1,CAMSAP1,AGAP2,GAB1,GLYR1,RAB30,HTATSF1,KCNMB4,GNAS,IL6R,IL6ST,VWA5A,MMP16,ADAM22,NF1,NFYA,PDE3B,SERPINE2,STRN3,POLG,EMID1,SGK1,CPEB3,FAM214B,KDM4C,PLCB1,TBCEL,PSD3,TMOD1,TMPO,TRIO,FAM155A,PLPPR2,WNK1" Drug 2572_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.08E-08 1.02E-03 1.27E-06 1.45E-05 61 192 "KIDINS220,MTUS1,EPB41L5,BMP7,HIP1R,SLC16A4,CD86,CD38,CDC42,CLGN,CHRM4,CREM,CRMP1,SIPA1L1,PDE4DIP,SLITRK5,PPP1R16B,CTNND1,DOCK4,MFAP3L,TMCC2,ING4,COQ7,EPHB1,CEND1,F5,FGFR3,FYB1,GPR19,PADI2,TJAP1,MEF2C,ZNF862,PDE4B,PLCD1,PLEC,MAPK8,MAPK10,PTK2,PTPRB,PTPRN2,MYH14,RXRA,TRAPPC13,ZNF821,DOCK10,SLC2A5,FAM214B,ARHGEF40,SPTAN1,LHPP,ATP10B,EPB41L3,SEPT8,ARHGEF9,CUX2,SZT2,AHCYL2,TPM1,FLRT2,LAT2" Drug 1209_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.08E-08 1.02E-03 1.27E-06 1.45E-05 61 192 "APBB2,ARNTL,MARK4,ST3GAL5,SCAPER,FOXN3,CHN2,RAB28,NMT2,AKAP5,PDE4DIP,SLITRK5,DNAJC6,C2CD2L,PLPPR4,TMCC2,FYN,STON1,GUCY1B1,DIPK1A,ITGA7,MAPT,OPCML,PDGFRA,PFKFB4,PIK3R1,RETREG1,PTAFR,PTCH1,RAB3A,ENOX1,GAL3ST4,RGS4,NUDT11,FBXW7,RXRA,SATB1,RASA3,ITSN1,SH3GL3,SYBU,ZNF365,BTBD7,TNIK,TSNAXIP1,SPTB,ELOVL4,PHLDB1,VPS13A,SYT1,COBL,SMG6,TRIM2,TGFBR3,HEY1,UGT8,DNAJC12,MICAL1,WNK1,FZD3,PHTF2" Drug 6207_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.08E-08 1.02E-03 1.27E-06 1.45E-05 61 192 "ARID1A,CDC42BPA,PPFIA1,APP,MARCH3,CFLAR,MTMR2,CNOT8,CHD1L,NCOR1,ABCG1,FEZ1,CSNK1E,PPP6R2,DCAF8,GIT2,LYPD1,MAMLD1,MRNIP,EPB41L2,FGFR3,CAMKK2,ZNF276,GPR19,NR3C1,BTN2A1,KIF3A,RBPJ,BRINP3,JAK2,KIF2A,MAPT,MIA2,NFYA,LRRC49,RIPOR1,RGS3,MYH14,FOXRED2,MAPK12,SUPT20H,FBXO11,SIRT2,TMCC1,EMC1,ITPRID2,FAM168A,TCF7,TCF7L2,PSD3,CBX5,TMPO,KAT6B,TNNT1,UBTF,VAV1,NSD2,ZBTB38,EVI5,MVB12B,FZD3" Drug 6551_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.08E-08 1.02E-03 1.27E-06 1.45E-05 58 179 "ADRB2,NME5,BMP7,ST3GAL5,SCAPER,BAIAP3,CDH18,CLGN,WHRN,PDE4DIP,DZIP3,RIMS3,ARMCX2,DNAJC6,EFNA3,EFNB3,STX2,CDKL3,ACSL4,TUBB4A,BAIAP2,DPYSL4,FYN,INPP5K,CYP46A1,GLS,STON1,KIF5C,NAP1L3,PCDH9,SERPINI1,PIK3CD,GRAMD1C,PRPH,RAB3A,SH3BGR,SH3GL3,ZNF365,WDR47,PKNOX2,ZCCHC24,KIF21B,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,TACC1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,SLC17A7,ITM2C" Drug CID005126051 AC1NNRU4 Stitch 2.26E-08 1.11E-03 1.38E-06 1.57E-05 22 41 "ADORA1,BSN,CNR1,FOXM1,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,LIMS1,MAP4,PENK,SHANK2,TAC1" Drug ctd:D011189 Potassium Chloride CTD 2.33E-08 1.14E-03 1.39E-06 1.58E-05 43 117 "ACHE,SLC12A5,ATP1A3,CACNA1A,CACNA1B,CACNA2D1,CAMK2D,NRXN3,NRXN2,CNR1,EDN1,EDNRA,EDNRB,PTK2B,FGF1,NPTN,GAP43,PPARGC1A,GNAS,GPD2,RAPGEF4,GRIN2D,NR3C1,GSTT2,IGF1,KCNA1,KCNA4,KCNC1,KCND2,MAPT,NPY,PENK,PKD1,MAPK3,MAPK9,MAPK10,SNAP25,PDZD2,SYN1,SYT5,TAC1,TPM1,SCG2" Drug 6412_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASIC2,ADRA1D,NME5,ADGRF5,BEGAIN,TRMT9B,APBB2,PLA2G4C,MARK4,ATP2B2,PROM1,CAMK2B,LDB2,TPP1,WHRN,RGS6,DCT,EXOG,SNX29,EFNA3,C3orf18,RASGRP2,DLC1,OLFM1,CAMSAP1,AGAP2,PDLIM5,TMEM8B,LPAR4,GPER1,PCLO,NR3C1,ATXN2L,ICA1,C2orf72,ITIH2,MAN2A2,MDFI,MYT1,PCBP3,NTRK2,PALM,PIK3CD,SLC25A23,NECAB2,PPP5C,PKN2,MAPK10,PTAFR,RGS12,RASA3,SLC6A8,SLC6A11,CDK19,SPART,MAPK8IP3,ARC,ATP11A,KIAA0930,AHCYL2,TUBB1,KCNAB1" Drug 6389_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "C1QTNF3,PKP4,APAF1,APOC1,CDK10,PRX,PPP4R4,PDE8B,DNAH17,ADGRB2,BCHE,SYNJ1,CBFA2T2,ARHGEF2,ARHGAP33,COL9A3,SDC3,SPOCK2,GIT2,ELN,PLEKHO1,NCALD,ZNF391,ETV1,CORO2B,SORBS1,PDLIM5,FYB1,SIGLEC8,POLL,GNG4,LILRB4,GRM3,HSF2,ICA1,KCNMA1,KPNA5,MAP2,NF1,PALM,PDE4B,PENK,PTCH1,PTPRE,FAM120C,FAT4,RGS12,CARF,FBXW7,HUNK,SLC2A5,PKNOX2,SLC6A11,SLC11A1,UNC5B,COLGALT2,SLC35G2,AP4E1,TRIO,NDRG4,SLC17A7,EPM2A" Drug 3168_UP Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "BIN1,APP,ARHGDIG,RGS20,ALDH4A1,MTMR3,MYRF,BTRC,CFAP410,HAP1,CAMK2B,ARHGEF2,TPP1,LY86,NOS1AP,PYGO1,BRINP1,NTM,DTNA,DUSP9,EDN3,DLC1,FYB1,SEPT9,ATP8A2,GATM,NEU3,PCDH17,GNAL,GPM6B,GPR17,GRIK4,NR3C1,GRM8,GSN,SOX21,KCND3,KCNQ3,MITF,LRRN3,DCHS2,PTX3,MYH14,SH3GL2,CPEB3,SLC4A3,SLC6A8,SORCS3,SP2,ZC3H13,INKA2,MAPK8IP3,PLCB1,SYT5,ROBO3,SLC19A3,PSD3,AMACR,MKRN3,TFIP11,SCG2,SLC17A7" Drug 3255_UP Metrizamide [31112-62-6]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "NDRG2,NME5,APP,ASPH,ZBTB10,ATP2A2,ALDH7A1,MTMR9,ATP6V0A1,ADAM15,GYG2,CLGN,ENTPD4,RIMS2,RIMS3,SPOCK2,C2CD2L,ATN1,DTNA,DUSP9,FCF1,FRY,MRNIP,SPEG,FGFR1,GLYR1,GPER1,GSTM5,KCNH2,LMO2,MDM4,KITLG,ZNF862,NFYA,NUMA1,PFKFB2,SLC25A23,STRN3,CNNM2,ELOVL2,RAD51D,C1orf54,KCTD17,KLHDC8A,FBXO11,SLC11A1,CDK19,TSPYL2,NXT2,PHLDB1,SYNE1,TK2,TMOD1,TMPO,DAAM2,KCTD2,TRPC1,WIPF1,LAT2,SYNC,PRDM2,NUP214" Drug 7012_DN Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASPHD1,ADD1,APOC1,PPFIA3,CDC14B,ARRB2,CDK13,ZBTB10,MPDZ,CCNT1,TMEM184B,HOMER3,CREM,DCAF8,DAPK3,GIT2,B3GAT3,MED24,SMG7,SGSM2,TRAPPC9,DSCAM,FEM1B,EFNA3,VPS26C,FGFR1,BAIAP2,MPP6,FYN,B4GALNT1,MALT1,COPS8,MSL3,GPR37,DHX35,HSD17B1,IL6ST,KHK,MITF,NFYA,NUMA1,OGG1,SLC25A23,SMIM7,FSD1,SEC14L1,SUPT20H,SYBU,BTBD7,FCHO1,DIP2A,MCF2L,TBL1X,TCF7L2,ARHGEF12,HIRA,UBTF,VAV1,LMF1,FTSJ1,GDPD5,VPS35L" Drug 3719_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "LTBP4,APAF1,CDK10,PRX,DNAH17,ATP2B2,BMP7,GYG2,CDK5R2,KALRN,ZFYVE9,NCOR2,CSF1,NOS1AP,RIMS3,DAPK1,MFAP3L,SV2B,NTM,RABGAP1L,DMD,ATN1,DYRK1A,EPHA5,ETV1,KAT8,KIAA1109,AGAP2,GAD2,GPR19,MAP4K5,NXPH3,MEF2C,ADAM22,MSR1,MYT1,NNAT,NPPA,OPCML,CDK18,PDGFRA,GPR173,NECAB2,PPP2R2B,CEP41,PRKAR1B,PRKCB,CSRNP3,FNDC3A,ZNF334,SLC15A2,NPAS3,INKA2,SYT11,RPGRIP1L,HIF3A,TK2,R3HDM1,TNS1,CDK20,RPRM,LAT2" Drug 2433_UP Felodipine [72509-76-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA1,MTUS1,SEMA6A,BCAS1,PPFIA3,KIF1A,FGF17,BMP7,CACNA2D1,CACNG1,CDH2,CACNA2D2,ZFYVE9,CREM,AATK,SIPA1L1,DZIP3,CTNND1,RIMS2,CNIH3,RABGAP1L,DSCAM,ST8SIA3,SORBS3,ERBB2,TBC1D16,KIAA1109,HPCAL4,GPM6A,PCLO,HTR5A,TJAP1,KCNH1,KCNN1,ADAM22,MX1,MYO6,FXYD6,NFYA,NOVA2,NTRK2,PLP1,MAPK7,PLPPR1,PTHLH,TTLL7,SEC61A2,SUGCT,SYNDIG1,SEMA6D,SH3BGR,SOX15,SEPT8,RPGRIP1L,ATP13A2,TRPC3,FLRT2,FLRT1,LMF1,MKRN3,SLC30A3,NUP214" Drug 5583_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "DPF1,ADRA1B,AMPD3,APC,ATP2A2,CFAP410,CAMK2B,CHN2,CLCN4,CNTN1,CSF1R,PDE4DIP,RIMS2,KBTBD11,DUSP9,SGK2,EFNB3,ING4,ELAVL3,VPS13B,NRN1,ZNF589,FGF13,FGFR3,FHL1,AFF2,PDLIM5,GAD1,SIGLEC8,PCDH17,GLYR1,GNAS,GPR37,GRM1,KCNK2,KCNN2,ADAM22,MSR1,MYO7A,NNAT,PDPK1,PLTP,LRP12,LRRN3,CEP41,ZMAT4,KCTD17,RYR1,DOCK10,ATP10B,SAMSN1,RGL1,PLCB1,MCF2L,DMXL2,TRIM2,SZT2,CRTC1,HEY1,PDIA2,SLC30A3,KCNAB1" Drug 6211_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASPHD1,ABHD6,AP2A2,AMPD3,ANK1,SLC4A4,ALDH7A1,ARHGEF2,CRLF1,ADGRG1,ZFYVE9,PLAA,FADS2,CRY2,NCOR1,DZIP3,DAPK1,GIT2,SPATA2,DSCAM,RCAN1,VPS26C,FGFR1,PDLIM5,OGA,TRAF3IP2,GAD1,HNMT,DHX35,INPP5B,MPP2,NF1,NFYA,PIK3CD,RETREG1,STRN3,PPP5C,PRKAR1B,MAPK8,PRPH,VPS13C,RAB3A,RALGDS,ATG16L1,ZDHHC14,RGS10,RYR1,ZFP30,SYBU,BTBD7,SLC22A4,SPTAN1,ZBTB43,TTBK2,STX1A,SEMA4A,TCF7L2,PSD3,CABIN1,SEMA3B,EPM2A,ST7" Drug 3897_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "DPF1,ALK,TRMT9B,AMPH,CDC42BPA,APAF1,RUNX1T1,CDC42,CHM,CNTN1,WHRN,OSBPL3,ARHGAP24,SPOCK2,DBT,PLXNC1,LRRC17,CEND1,FGFR3,FOXF2,SEMA4D,ANKFY1,PDLIM5,GAD1,GAD2,DISC1,KLF12,HLF,TJAP1,KCNJ5,L1CAM,MATN3,ADAM22,MX1,P2RY13,NOS1,CLDN11,PAH,PDE1C,CDK14,CEP41,PRKCB,ELOVL2,RPS6KA2,SYNDIG1,KCNIP1,ZFP2,SH3GL3,LIMS2,RBM34,SPP1,PEG10,LMO3,TBCEL,PCDHGA10,PCDHA5,DICER1,HEY2,TMOD1,LILRA4,UBE3A,WIPF1" Drug 6011_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA1,AMPH,BIN1,DDO,CDK13,MARK4,BRINP2,CACNA1G,CAMK2B,CDH10,CHRNB2,WHRN,NECTIN3,HAPLN1,PDE4DIP,DCAF4,MAML1,ELMO1,ATN1,DTNB,ST8SIA3,EDNRA,EDNRB,EGFR,VPS13B,GAB1,SRCAP,GFAP,GRK4,HRH3,HNMT,KCND3,KCNN1,MAN2A2,MAPT,MOBP,MYCN,NCAM1,NNAT,PDE3B,CAMKV,RETREG1,MAPK7,GRAMD1C,PTAFR,ZSCAN2,ZDHHC14,SCN2B,RASA3,RPH3A,SLC11A1,SMARCD3,WDTC1,ZCCHC24,UNC5B,ZNF423,KIAA0930,PCDHGA1,PDIA2,PLPPR2,ITM2C,CAMK1G" Drug 6054_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "DPF1,AGT,MRTFA,AMPD3,APBA2,MARK4,RASL11B,ATP2B2,ADGRB3,CACNA1G,CBARP,ARHGEF6,PICK1,AKAP7,WHRN,COL9A3,HAPLN1,RGS6,NCAN,PDE4DIP,SDC3,CTIF,DCC,DPP6,ST8SIA3,EDN3,EDNRA,ZNF589,FGF1,FGFR1,FHL1,GPER1,GRM8,HLF,HPSE2,TJAP1,KCND3,KCNJ4,KIFC3,CD200,MYO7A,NEUROD1,NPPA,NPTX1,P2RY1,PGAM2,PURG,FAM120C,TTLL7,SYNDIG1,ST6GAL1,SLA,SHANK2,ZCCHC24,DOK5,CAND2,HECW1,MAPK8IP3,SMG6,DAAM2,TPM1,PARP11" Drug 3781_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "LTBP4,DOC2A,EPB41L5,GAS7,ALDH7A1,BMP7,BTRC,HAP1,CBS,ARHGEF1,NEURL1,CHM,PLAA,ABCG2,IQCK,HAPLN1,SEC14L5,RIMS3,MFAP3L,SMG7,DLG3,DUSP9,EDNRA,SGK2,ETV1,DCTN2,CGREF1,CSPG5,OGA,GAD2,ICA1,IL11RA,IL12A,KIF5C,ZNF862,NDUFA5,NELL2,NF1,NOVA1,PCDH9,PTPA,PRKAB2,RAD52,GAL3ST4,RGS4,KCTD17,TCP11L1,DZIP1,ZNF334,SLN,UNC5B,ATP10B,COLGALT2,ROBO3,TBCEL,TRIM2,TIMP4,TPM1,VGF,VLDLR,MPPE1,DPF3" Drug 6062_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "NME5,LTBP4,BEGAIN,AMPD3,AMT,GAS7,PLA2G4C,CACNA2D1,ARHGEF6,SNPH,DUSP9,SPEG,F5,REEP2,FGF13,FGFR1,GAP43,LYVE1,STON1,CACFD1,GRIN2C,TJAP1,CD200,MX1,NPY,NOVA2,PALM,TMOD2,PFKFB2,PLCD1,MTRF1L,LRRN3,PLPPR1,ZNF493,RGS12,MYH14,TCP11L1,KCNIP1,SLCO1A2,SNAP25,WDTC1,HECW1,UNC5B,ARHGAP26,SPART,LMO3,ST5,INKA2,ARC,ATP11A,KIAA1107,CRTC1,HIF3A,DNAH7,HEY2,DAAM2,RUNDC3B,PDIA2,VSNL1,STMN4,SCG2,NUP214" Drug 5701_UP Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "APAF1,APC,DDO,APOC1,SEMA4G,ASCL1,ALDH7A1,N4BP2L1,CACNA1I,CACNA1D,TMEM257,NRXN3,CLCN4,IPCEF1,CNTNAP2,RASSF2,DCC,HS3ST2,EDNRA,EFNB3,NRN1,ZNF589,FGFR1,CAMSAP1,AFF2,SORBS1,FYB1,GABRA5,GAD1,GLS,GRIK1,GRIN1,GUCY1A1,KCNJ5,ADAM11,MDFI,MYO7A,PCBP3,P2RX7,PALM,CAMKV,NECAB2,PPP1R1A,LRRN3,PTCH1,PTX3,CEP97,TCP11L1,SH3BP2,FAM214B,SLC11A1,SLN,FAIM2,PEG10,ATP10B,TTBK2,SYN2,TRIM2,PCDHGB6,SYNE1,SLC35G2,DICER1" Drug 4729_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "RALGAPA1,ASIC1,ADCY2,LTBP4,MRTFA,AMPD3,BIN1,APC,APOC1,ARRB2,CDH2,CDO1,CACNA2D2,CNN3,CNTN1,NECTIN3,RGS6,CNTNAP2,ARHGAP24,SPOCK2,RUSC2,DMPK,EML1,RASGRP2,DISC1,NEU3,ALDH1L1,GNAL,PCLO,HPSE2,KCNH2,MAPT,MATK,MATN3,LRP1B,AFDN,MOBP,NF1,CDK14,PLCD1,MAPK7,RELN,PTCH1,ELOVL2,ZSCAN2,RAB3A,RORB,SLC14A1,MYH15,SNCA,KDM4B,ZCCHC24,ZSWIM8,PEG10,ARHGAP26,MAPK8IP3,DAAM2,OSBP2,BCL2L13,KCNK12,SLC30A3,AP3B2" Drug 2522_UP Napelline [5008-52-6]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "TKTL1,APC,DDO,CCDC181,ALDH7A1,RGS11,SYNJ1,CACNA1I,B4GALT6,LHX2,EPS15L1,RAB33A,NRXN1,CLU,NMT2,DNAJB5,TCEAL2,CSF1R,NCAN,DZIP3,ZNF337,BRINP1,B3GAT3,MFAP3L,PLXNC1,DMTN,DLC1,ZMYND10,KIAA1109,AFF2,DENND2A,NEU3,ALDH1L1,LYVE1,GNAL,ATF7,LILRA2,GPR37,KCNK1,KCNN1,TAGLN3,MYO7A,NCAM1,NOS1,NTRK2,EPB41L4B,PRKCZ,PROX1,MARCH1,SCN8A,SEC14L1,ASAP3,NLGN1,SLC1A3,SHANK2,SYT1,EXOC7,DOCK9,TRO,OSBP2,LMF1,PMEPA1" Drug 4629_UP Droperidol [548-73-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ABAT,ASCL1,KSR1,BMP7,SYNJ1,CACNA2D1,CALB2,KALRN,CAMK2B,FOXN3,CHGA,SOCS6,NRXN2,DNAJB5,COL9A2,CRMP1,ARHGEF10,PHYHIP,KIAA0753,PLPPR4,EXOG,EDNRA,CNNM1,PLXNC1,PLEKHO1,RASGRP2,EZH1,DCTN2,PRELID3A,ARPP21,GNAL,GPD1,RAPGEF1,GRM8,BACH2,PACRG,MMP16,NF1,CNOT4,NOVA2,PDE4A,MTRF1L,SCN3A,FUZ,PREX2,ARHGEF40,SNCA,BEX1,ARHGAP26,PHLDB1,COBL,TAL1,TCF4,DOCK9,DNAH7,CADM1,VGF,PRDM2,SCG2,CAMK1G,DPF3,JPH3" Drug 6041_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASIC2,AMPD3,BIN1,LGR5,ASCL1,ALDH7A1,FGF17,CACNA1G,CALB1,KALRN,ADGRG1,DNAJB5,RIMS2,TOX,DYRK1A,AASS,CEND1,TUBB4A,ST3GAL6,FHL1,GAP43,PRUNE2,GRK4,GRM8,GUCY1A1,HAS2,HRH3,HLF,IRF8,IFI16,KCNC1,KCND3,KCNJ5,KCNMA1,AFDN,ADAM22,OPCML,PCDHGC3,PPP1R1A,RELN,SAMD9,PTPRO,FAM120C,FRMPD1,SLC1A7,SNAP25,BEX1,MAPK8IP3,ARC,SYT5,PCDHGB6,FAM189A1,OBSL1,LILRA4,TRPC3,OSBP2,MICAL1,LAT2,PRDM2,SCG2,TIGD6,JPH3" Drug 6273_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "BRAP,AGT,APC,ARHGDIG,SLC4A4,CFLAR,ST3GAL5,SYNJ2,CACNA1D,VAX2,QKI,ARHGEF10,ATRNL1,PDE4DIP,GREB1,ARHGEF4,DMD,DMPK,DRD1,HIPK3,MBNL2,EPB41L1,STX2,ZNF589,PDLIM5,KHDRBS3,FYB1,SRCAP,CACFD1,GRM1,MUM1,INPP5B,ITPKB,MAP4,AFDN,MPP2,NF1,CDK18,PDE3B,RETREG1,PLEC,PPP2R2B,GRAMD1C,ATG16L1,ZCWPW1,KHDRBS2,GSTCD,FBXW7,RPS6KA2,PEX26,NCDN,MAPK8IP3,PHLDB1,ARHGEF9,SEMA4A,RPGRIP1L,CHST5,ZKSCAN5,PLPPR2,GDPD5,HPS4,ST7" Drug 4017_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADD2,AP2A2,BBOX1,ARHGDIG,CDK13,BTRC,CBFA2T2,CHM,CLCN4,TPP1,CNTFR,ENTPD4,HAPLN1,SPOCK2,DTNA,HIPK3,FRY,EPHA5,ETV1,PTK2B,FGFR1,NSG1,SIGLEC8,PCDH17,GPM6B,GPR17,GRIK2,CACFD1,IL12A,INPP5B,MATN3,NPTX1,NUMA1,ENPP2,PLCD1,PPP2R2B,PTPRB,PTPRN2,C1orf54,ARID4A,BEND5,RFX2,RGS12,KLHL11,GSTCD,NEK11,DOCK10,RIMS1,TNIK,SPTAN1,SPTB,SYT5,MCF2L,SLC44A1,TPM3,CHST5,ZNF24,WNK1,KCNAB1,PARP11,PHTF2,DPF3" Drug 5681_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA2A,ANK1,APAF1,ASTN1,CADM3,AZGP1,CFLAR,CACNA1D,CHI3L2,CHRNA4,AATK,IPCEF1,CNTNAP2,RASSF2,SNAP91,SPOCK3,SGK2,TENM1,ERCC2,NRN1,CAMSAP1,FHL1,CSPG5,GABRA2,SIGLEC8,ALDH1L1,NR3C1,GRM8,CELF3,ATXN2L,KCNA2,KCNH2,MATN3,MMP16,ADAM22,MYT1,NOVA1,NPTX1,NTRK2,P2RY1,LRP12,SEPT4,PTPRD,NKAIN1,RGS12,ZFHX4,ZFP2,PPP1R9A,LIMS2,MAPKBP1,PEG10,PSD3,CRB1,HEY1,R3HDM1,PIK3R5,PRMT8,TRPC1,SLC30A3,SLC30A4,PARP11,SSPN" Drug 5741_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "SYN3,PLA2G6,APAF1,LGR5,AQP4,CACNA1A,CACNA2D2,PLEKHB1,TAOK2,NRXN3,RAB26,CNR1,CNTN1,CNTNAP2,PYGO1,RIMS3,DAPK1,MFAP3L,AK5,EXOG,PLXNC1,ERAP1,GPM6A,STON1,GRIN1,GSTM5,AP4S1,VWA5A,SMAD1,ADAM11,AFDN,MMP16,MSR1,LYRM9,NDUFA5,NF1,NTRK3,PALM,PCDH9,EPN1,NEK11,KCNIP1,SEMA6D,SELL,SLC6A8,SLC15A2,OGDHL,TSNAXIP1,SPTAN1,DDN,ACSBG1,PCDHGA10,SYNE1,DOCK9,TNS1,AMACR,RPRM,OSBP2,VAV1,ZBTB14,SLC30A3,SEMA3B" Drug 4160_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASIC1,ADORA1,SEMA7A,CDK10,PDE8B,ASPH,RASL11B,CFAP410,CACNA1D,KYAT1,RCBTB2,ASIC3,SLIT2,NMT2,HOMER3,SLC4A7,SH2B1,CRY2,SNCAIP,RIMS2,DCAF8,MAML1,TMCC2,DNM2,HIPK3,SIDT2,EFNB3,EZH1,ATP8A1,BAIAP2,FHL1,KHDRBS3,GPR153,GNG4,PRRC2B,RNFT2,IGSF1,INPP5B,ITIH2,KCNH2,VWA5A,SMAD1,MAP4,MPP2,NOS1,SETD4,NLE1,PLCD1,LRP12,GRAMD1C,TRIM68,SH3BP2,SLC9A5,SNCA,ZCCHC24,CDK19,ZBTB43,TROVE2,PLCB1,POPDC3,RUNDC3B,TRPM2" Drug 6059_UP Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "SYT13,BIN1,CDC42BPA,ANK1,GAS7,ARHGDIG,ALDH7A1,SCAPER,INA,RAB33A,VCAN,CNTNAP2,SPOCK2,BRINP1,RUSC2,SPOCK3,NTM,HS3ST2,ATN1,DSCAM,HSD17B14,ST3GAL6,FGFR1,GFER,GSN,ICA1,SHISAL1,IGFBP1,TJAP1,ITPKB,KCNJ5,VWA5A,MAOB,TM6SF1,BCO1,NPY,SLC11A2,PCSK5,PFKFB4,POU6F1,LRRN3,PRKCB,PTAFR,PTPRO,ZSCAN2,CARF,S100B,SELL,CPEB3,SLC1A6,PEX26,ARHGAP26,ATP10B,INKA2,PCDHGA10,R3HDM1,TRO,FLRT2,SLC13A3,SLC30A3,MVB12B,JPH3" Drug 4355_DN Homosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA1,ADRA1D,C1QTNF3,AMH,PDE8B,CADM3,ADGRG1,B4GALT6,WHRN,ABI3BP,SDC3,MAML1,SLC12A6,DRD1,MBNL2,EIF4G2,SORBS3,OLFM1,SCARA3,FOXG1,AGAP2,GPR153,DISC1,RUNDC3A,GLYR1,GNAS,HNMT,ITIH2,KHK,KIT,IPO5,MAP4,MID1,ZNF862,NOS1,SERPINI1,RETREG1,PLXNB1,POLG,ATG16L1,TCP11L1,SUPT20H,ASAP3,FNDC3A,PPP4R3A,WDTC1,EMC1,KDM4C,CLSTN2,FAM168A,ATP11A,EXOC7,ZEB1,CRTC1,SLC44A1,HEY2,FLRT2,PLPPR2,MICAL1,NSD2,ZNF24,KAT6A" Drug 5083_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "PLA2G6,ANK1,PPFIA4,CADM3,ADGRB2,NRP2,BAIAP3,CA8,CACNA1A,CACNG1,THSD7A,BRSK2,RUNX1T1,SLC16A4,ENTPD2,DNAJB5,CNTFR,TRAPPC9,SHANK1,ST8SIA3,HEYL,MTSS1L,HPCAL4,AGAP2,AFF2,EFCAB2,ZNF44,GAD2,NEU3,RUNDC3A,MSL3,POLL,GNG4,GRM2,SOX21,PTGDR2,KCNF1,LSS,AFDN,MMP16,ADAM22,MSR1,NELL2,NF1,OPRL1,PID1,RGS12,IL17RB,FRMPD1,SLC6A11,KDM4B,SOX15,HECW1,ZNF423,SPTB,PHLDB1,RALYL,CHST8,LILRA4,ZMYND8,XRCC4,FAM13C" Drug 5280_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASPHD1,NDRG2,ADORA2A,AGT,BIN1,CDC42BPA,APC,SEMA4G,MARK4,ALDH4A1,ADAM15,BCL7A,NRP2,SYNJ2,CFAP410,ARHGEF2,CLGN,ZFYVE9,PICK1,WHRN,SH2B1,CNTNAP2,NOS1AP,TBC1D5,JAKMIP2,MFAP3L,LYPD1,DRD1,DTNA,EDN1,EN2,DMTN,PIPOX,FER,GPR153,GAP43,SRCAP,GLS,GPER1,PCLO,GRB10,BTN2A1,KIF5A,LMO2,MAOB,KITLG,NDUFA5,PENK,GON4L,PLPPR1,PEX5,RAB3IL1,RAD52,RPS6KA2,SBF1,SNCA,ZHX3,RGL1,TBCEL,TRIM2,ZNF34,WBP2" Drug 7037_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASPHD1,NDRG2,CDC42BPA,BCAS1,NUMB,CFLAR,ARHGEF7,CDH10,SIPA1L1,PDE4DIP,DZIP3,CTNND1,EDRF1,DCAF8,ZNF337,RIMS3,PARD6A,MED12,CDON,DTNA,MAMLD1,EFNA3,RBM12,F8,FOXG1,CRCP,GNG4,GRB10,RNFT2,KIF5C,MAPT,ADAM22,NEK1,NFYA,NUMA1,PPP2R2B,TMEM104,NKAIN1,RAD52,ZCWPW1,GTDC1,SH3BP2,ITSN1,FUZ,WDR47,SHANK2,SLC15A2,BTBD7,CDK19,SPART,MAPK8IP3,CEP68,MCF2L,TCF7L2,TMEM121,CHST8,BEX4,UBTF,ZNF142,TFIP11,PRDM2,GAN" Drug 6445_UP Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASPHD1,LGR5,PDE8B,ASPH,C5,CDK5R2,LDLRAD4,CFAP410,CACNA2D1,CAMK2G,SPAG9,ENTPD2,CLGN,CHI3L2,CHRNB2,KIAA1549L,CLCN4,QKI,ARHGEF6,IFFO1,HAPLN1,CSF1R,SDC3,DCAF4,HS3ST2,EDN1,AASS,CORO2B,KIAA1109,AGAP2,DCTN2,SORBS1,SIGLEC8,KLF12,HLF,ITGA7,KCNMA1,MBD1,AFDN,ADAM22,PLCD1,MTRF1L,LRP12,MAPK8,RALGDS,RGS7,SUGCT,TCP11L1,CPEB3,PPP4R3A,SNCA,ZCCHC24,KIF21B,ATP10B,SSTR2,SS18,WSCD1,PARD3,NSD2,ZFP37,ZNF24,ZNF45" Drug 6174_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA1,MTUS1,APAF1,PDE8B,DDX3Y,ATP2B2,PROM1,SYNJ2,BTRC,SLC24A2,CSF1,CSNK1E,PDE4DIP,RIMS2,KIAA0513,ATN1,SNX29,EDNRB,MRNIP,STX2,APC2,REEP2,OLFM1,FGFR1,GAP43,ADAM28,PCSK1N,PCLO,GUCY1A2,PADI2,IGF1,KCNA1,KCNA2,KCNH1,KCNK1,LMO1,MID1,ADAM22,TAGLN3,NELL2,SLCO1C1,NRCAM,RETREG1,EPN1,MINDY2,SYTL2,SEMA6D,SELL,SH3BP2,FAM102A,HECW1,CDK19,LHPP,TROVE2,TACR1,KIAA1107,SLC44A1,TRH,SLC13A3,ZBTB38,SEMA3B,PLSCR4" Drug 6817_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADORA1,AGT,MRTFA,ASPA,ATP2B2,AZGP1,RGS9,LDLRAD4,ARHGEF1,CHRNB2,RAB33A,STOML1,CNTN1,CPS1,OSBPL3,PLCH2,EDRF1,RIMS3,SPOCK3,SV2A,DMPK,EFNB3,ERCC2,ST3GAL6,ZMYND10,FGF13,CAMSAP1,HPCAL4,FYN,GABRG2,GAP43,SRCAP,MSL3,SPACA9,GRM1,GRM3,HLF,HNMT,ICA1,TAGLN3,NOVA2,NPPA,OPCML,C1orf54,TCP11L1,ZNF821,ASAP3,ST6GAL1,FAM214B,SHANK2,KDM4B,KIF21B,IZUMO4,TSPYL2,INKA2,MAPK8IP3,WSCD1,SEZ6L,RUNDC3B,SLC17A7,TIGD6,JPH3" Drug 5953_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ASIC2,ACTN2,NDRG2,ADORA1,ADORA2A,NME5,AK2,PLA2G6,ALCAM,AMH,BRINP2,ATP2B3,CACNA1I,BTRC,DAPK3,CTIF,SLC12A6,DTNA,TOM1,EFNA3,EGFR,EGR3,EIF5,HSD17B14,EN2,LRRC23,IGSF6,SCML2,DLC1,FGF13,INPP5K,RAB30,GNG4,GPR19,GRIN1,KCND3,KCNJ4,KCNN1,KHK,P2RY1,PALM,PLTP,NECAB2,PPP2R2B,PTHLH,PEX5,TCP11L1,RPS6KA2,WLS,SLC1A7,SLC9A5,SLC11A1,SLC22A4,KIF13A,ZHX3,EMC1,PHLDB1,MTCL1,TBCEL,FAM189A1,TF,NT5M" Drug 3311_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "AMPD3,APC,ATM,CCDC181,SLC4A4,CADM3,CFLAR,CACNA1I,CFAP410,CAMK2B,CBFA2T2,RCBTB2,FOXN3,TPP1,QKI,SULT4A1,SLC4A7,HP1BP3,SGK2,HIPK3,EGFR,ETV1,ZNF589,FGF13,POLL,GNG4,NR3C1,GRM8,ATXN2L,HPSE2,IL6ST,KCNMA1,KCNN1,ADAM22,NEFM,CNOT4,MTRF1L,NECAB2,PPARA,MAPK8,GRAMD1C,SAMD9,RAD52,KCTD17,GSTCD,SLC1A2,SLC9A5,FAIM2,WDTC1,SOX3,INKA2,PHLDB1,ARC,ARHGEF12,PCDHA5,ZNF34,THRA,UGT8,XRCC4,NT5M,EVI5,SENP7" Drug 6337_UP Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ACTN2,ADRB2,NME5,PLA2G6,LTBP4,APBB2,SEMA4G,PPP4R4,ALDH4A1,STX16,CFLAR,CFAP410,CD86,SCARB1,CHI3L2,NRXN3,CREM,ENTPD4,SH2B1,EDRF1,GPRASP1,SPOCK2,RCAN1,ST8SIA3,FAM13A,EGFR,ELN,FOXG1,TRAF3IP2,IQGAP2,ERAP1,GLYR1,MSL3,PRUNE2,GPM6A,SPACA9,SOX21,ATXN2L,HSD17B1,SHISAL1,TJAP1,KCNB1,VWA5A,ARHGAP12,MGAT3,MIA2,PDE4D,CDIP1,POLG,PPP5C,PTAFR,GAL3ST4,RNASEL,ROM1,SYNDIG1,RYR1,EXOC7,FAM189A1,CRTC1,PCDHA6,XRCC4,DPF3" Drug 2156_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ADCY2,MTUS1,SEMA6A,ALK,CASK,CADM3,NMT2,SULT4A1,CNTFR,AKAP7,WHRN,CRMP1,ABCG1,MICAL2,SIPA1L1,PDE4DIP,PPP1R16B,RUBCN,DOCK4,ARHGAP32,DNAJC6,C3orf18,EIF1,EPHB1,ZNF549,CAMSAP1,DCTN2,PRELID3A,TMEM8B,CSDC2,LILRA2,PADI2,KLF12,KCND1,MAP4,MEF2C,MIA2,N6AMT1,ZNF862,PDE4B,PMP22,PTPA,RIPOR1,RAB3A,RGS3,RGS4,TTLL7,SLC1A3,SLC20A2,ZC3H13,SPTAN1,SPTB,LHPP,CEP68,SYNE2,CAMSAP2,HIF3A,RUNDC3B,ZMYND8,FLRT2,CLIP2,ZIC3" Drug 2873_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-08 1.16E-03 1.39E-06 1.58E-05 62 197 "ARID1A,NDRG3,ADRA1B,PLA2G6,ALK,AMPH,APLP1,ATP2B2,CACNB2,CACNG1,NEURL1,DLGAP2,EPS15L1,TMEM59L,FADS2,FAM149A,ABCG1,CRYM,SNCAIP,ELMO1,ATN1,DYRK1A,SRCAP,PCDH17,GPR75,ATF7,NR3C1,ITPKA,KCNJ5,AFDN,NELL2,NNAT,NPY,NRGN,KCNK10,PDGFRA,GPR85,PACSIN1,RAD52,ZMAT4,TRIM68,MYH14,EMID1,SLC30A10,RASA3,PPP1R9A,FRMPD1,DOCK10,ST6GAL1,PKNOX2,ARHGEF40,SHANK2,SLN,IGSF9B,SPTB,NCDN,ARC,TMEM121,ZFPM2,EVI5,ITM2C,ADAMTSL3" Drug 3015_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.58E-08 1.26E-03 1.50E-06 1.71E-05 61 193 "CDC42BPA,CDK10,ATP2B3,AZGP1,FGF17,BAIAP3,THSD7A,HIP1R,RUNX1T1,INA,DGKI,CDH10,DLGAP2,TCEAL2,NRG2,PDE4DIP,DBT,SPOCK3,NTM,EXOG,HS3ST2,ST8SIA3,EDN1,EDN3,PLEKHA1,HSD17B14,EFS,FER,C1orf61,AFF2,PRELID3A,GABRA5,GALC,MYOZ2,GPR19,RAPGEF1,ATXN2L,SCIN,KIT,MYCN,MYH3,MYH7,NEFM,CNOT4,NTRK2,PDE4A,PMP2,STRN3,FSD1,PRKAR1B,RAB3IL1,EPN2,SLCO1A2,TAC3,PHF24,TMOD1,FLRT2,WNT7A,ZNF225,NUP214,GAN" Drug 5088_DN Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.58E-08 1.26E-03 1.50E-06 1.71E-05 61 193 "APOC1,ARNTL,MARCH3,ASPH,SLC4A4,ADAM15,CCNT1,CHM,CLCN4,HOMER3,SLC4A7,CREM,VCAN,FAM169A,SLITRK5,EDIL3,FCF1,OPTN,EFNA3,MBNL2,IRAK4,TUBD1,ETV1,VPS26C,RRAGB,KIAA1109,ANKFY1,TRMO,PDLIM5,GAD1,ERAP1,ARFIP1,SPIN1,NUDT21,IL6ST,INPP5B,JAK2,KCNN1,NFYA,CNOT4,NUMA1,CDIP1,STRN3,SAMD9,SYTL2,PTN,RAD51D,ZNF671,CSRNP3,CCDC88A,SLC14A1,SNCA,TNIK,BEX1,SS18,NXT2,VAMP1,TCF4,CABIN1,ZNF24,SMIM8" Drug 6579_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.61E-08 1.28E-03 1.52E-06 1.72E-05 58 180 "ABHD6,APLP1,MARK4,KIF1A,BMP7,ST3GAL5,BAIAP3,WHRN,AKAP12,PDE4DIP,CTH,DOCK4,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNA3,EFNB3,STX2,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,RAB40B,STON1,RNFT2,KIF5C,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,GRAMD1C,PRPH,SH3BGR,SH3GL3,ASAP3,SYBU,WDR47,PKNOX2,ZCCHC24,KIF21B,SPTAN1,THSD1,ELOVL4,RGL1,STX1A,STXBP1,ACSBG1,SYT11,HEY1,RUNDC3B,DNAJC12,REEP1,GDPD5,SLC17A7" Drug CID000000295 "guanosine 3',5'-cyclic monophosphoric acid" Stitch 2.64E-08 1.30E-03 1.54E-06 1.75E-05 141 577 "KCNH8,ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,DOC2A,MYH7B,ARRB1,ARRB2,PDE8B,ATP1A2,ATP1A3,ALDH7A1,RGS9,HCN2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,PRC1,CCK,KRIT1,CD38,LRBA,CACNA2D2,CHGA,CHRM1,SLC22A6,SLC24A2,MYL6B,CNGA3,CRY2,DCC,DMD,DNAH9,SLC25A18,ABCC5,E2F6,EDN1,EDN3,EDNRA,EDNRB,PHC2,CACNG7,KCNMB2,NCALD,MRVI1,EZH1,CACNG2,SCML2,PPP1R1B,ACTL6B,IP6K2,DOT1L,GFER,CRCP,KDM2B,KCNMB4,GRIK1,GRIN2C,GRIN2D,ATE1,GUCY1A2,GUCY1A1,GUCY1B1,HBA1,TNFAIP8L3,HSP90AA1,MYLK2,KCNH2,KCNMA1,KIFC3,MYL3,NBL1,NEUROD2,NOS1,NPPA,NPR2,HCN1,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,CDK14,PHKG1,PKD1,PKM,PLCB2,POLR2F,PPARA,PTPA,PRKACB,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK9,PRPH,RPE65,RYR1,RYR3,MAPK12,SLC6A7,SCMH1,GKAP1,SMARCA4,PEG10,SAMSN1,SEPT3,MLC1,PLCB1,TAC1,TAC3,TBL1X,USP22,ACTR6,TMPO,NTSR2,VSNL1,ZIC3,SCG2" Drug ctd:C020806 tetrabromobisphenol A CTD 2.66E-08 1.30E-03 1.54E-06 1.75E-05 203 900 "ASIC1,ACLY,SLC25A25,NDRG2,ELFN2,ADORA1,ADRA1D,HECW2,OSBPL6,SORCS2,USP35,ALCAM,PCDH10,SEMA7A,APBB1,APP,SHROOM2,ARNTL,RGS20,ASPA,DACT3,CCAR2,ATP2A2,CACNA1G,LDLRAD4,CACNA1A,MAP7,RUNX1T1,CBS,USP2,CD86,REPS2,CBARP,CHM,CHN2,PLEKHB1,MS4A7,CHRNA4,CHRNB2,ABCG2,TBPL1,RASGEF1C,CTH,BOC,HDAC9,HDAC4,DGKG,ZBTB24,ELMO1,RUSC2,C2CD2L,KBTBD11,RAB39B,DPYSL2,ABI1,DNM1L,E2F6,SGK2,FRY,FAM13A,EGFR,SRPK3,STARD3NL,OLIG2,ENO2,LRRC17,ERBB2,TMEM74,DUSP27,FABP7,SH3YL1,TUBA1B,TUBB3,TUBB4A,FCGR1A,CHST15,FCGR3A,FCGRT,FGF1,FGFR3,AMOTL2,CAP2,SORBS1,GPR153,ADGRA1,TVP23A,GAA,GAB1,GABRA1,GABRG2,FAM184B,GCNT2,GFAP,KIRREL3,BRD8,RND1,LILRB4,GPR17,LPAR4,GPER1,EML4,GRIK2,NR3C1,GRM1,ATOH8,AGFG1,HSPA1L,IGF1,GAREM2,KCNA2,KCNB1,KCNH2,VWA5A,FGFBP3,NCOA7,NAT8L,MAP2,MEF2C,MGAT3,MMP17,MOV10,CD200,SAMD5,MYO7A,NCF2,RCOR2,NEFH,NOS1,NRCAM,PDE1B,TMOD2,ABCB1,PLIN1,SLC25A23,PLXNB1,PMP2,PMP22,STRN3,POU3F2,PPARA,MAPK3,MAPK8,MAPK9,SLC26A11,PRPSAP2,MASP1,SYTL2,GDPD2,PTCH1,PTHLH,PTPRN,RAB3IL1,FAT4,KLHL11,SETD5,RORB,RTN1,ZNF354C,RYR1,S100B,FNIP1,ELMOD1,SH3BGR,FAM102A,SMTN,NAPB,CPEB4,ANKRD36,LIMCH1,SNAP25,FAIM2,SOX2,SPP1,ARHGAP26,ZC4H2,ST5,ACSBG1,SYT4,DDHD2,IQCE,TMEM136,AKNA,GPRIN3,THRA,NACC2,TLR4,TMPO,DAAM2,PIK3R5,TPM1,ZNF346,TRH,RPRM,PLEKHH2,VIPR2,VLDLR,PCDH20,ZFP41,NDRG4,SPHK2,RGMA,PLSCR4,KLHDC1" Drug 3973_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "DPF1,C1QTNF1,SEMA6A,BEGAIN,PDE8B,ADAM23,KSR1,GYG2,CACNG1,CDH10,LHX2,TPP1,WHRN,SNCAIP,NOS1AP,DCT,DNAH9,EDNRA,SGK2,HIPK3,SORBS3,PTK2B,FGFR1,GPR75,SPACA9,GRIN1,GRM7,NXPH3,PTGDR2,KLF12,IRF8,MOBP,NEUROD2,NPTX2,NTRK2,PCDH8,PIK3CD,POU6F1,CEP41,MASP1,RFX2,ASIC4,STUM,ST6GAL1,CNKSR2,ZNF334,SNAP25,PDZD2,NMNAT2,LMO3,PHLDB1,ATP11A,TACR1,TCF4,DOCK9,OBSL1,ICAM5,CHST5,PDIA2,MVB12B,DPF3,AP3B2" Drug 3624_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ADORA1,MRTFA,MARK4,BAIAP3,CFAP410,CAMK2B,LRRFIP1,SULT4A1,WHRN,TCEAL2,CRY2,ELMO1,SV2B,SRGAP3,KBTBD11,DPP6,DYRK1A,EDIL3,RASGRP2,PTK2B,KIAA1109,C1orf61,AFF2,FYB1,FYN,HBS1L,GFAP,ADAM28,GPER1,HPSE2,HTR2A,ITGA7,KCND3,LSS,MAP4,MEF2C,NNAT,NPPA,NPTX1,OPCML,PAH,PENK,CDK14,RETREG1,PACSIN1,CEP41,S100B,SLC30A10,SLC8A1,SLC11A1,OGDHL,TSNAXIP1,ACSBG1,ARC,ZEB1,SZT2,TMOD1,TRIO,FLRT2,VIPR2,SPHK2,PRDM2" Drug 6495_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "NLGN4X,AK2,SEMA6A,AMPH,PPP4R4,N4BP2L1,NRP2,NGB,CAMK2B,CDH2,SLC24A2,TPP1,CNTN1,AKAP7,RASSF2,DAPK1,SPOCK2,ARMCX2,DCT,HEPH,HP1BP3,ECM2,USH1C,EPHB1,DLC1,FGFR3,FHL1,AGAP2,DENND2A,SIGLEC8,GSTM5,SOX21,SHISAL1,LSS,MBD1,MDFI,MDM4,MID1,ADAM22,TAGLN3,MYO7A,NTRK3,PALM,SEPT4,PPP5C,PTPRB,KCTD17,NUDT11,TSNAXIP1,SP2,ARHGAP26,ARC,EXOC7,TRIM2,DOCK9,TLR4,TNS1,UGT8,VAV2,WIPF1,XRCC4,STMN4" Drug 2294_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "TKTL1,ADORA2A,MRTFA,BIN1,GAS7,APLP1,PTCH2,CALB2,ARHGAP33,LHX2,KIAA1549L,SLC24A2,FADS2,ARHGEF6,PICK1,RASSF2,SPOCK3,ATN1,ABCC9,LPAR6,CORO2B,TPK1,GPR153,GAB1,GAD2,GPR75,GLS,GNAO1,SOX21,ITGA7,KCND3,IPO5,MDFI,MID1,MOBP,NNAT,NTRK2,CLDN11,PDE4B,PLTP,SAMD9,PTCH1,KHDRBS2,GAL3ST4,KCTD17,NUDT11,SLC6A8,SHANK2,CXXC4,UNC5B,ZC3H13,SPTB,ZBTB43,INKA2,MAPK8IP3,JMJD6,CRTC1,GPR161,TNS1,SEZ6L,TPM3,VIPR2" Drug 5257_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "KLRC4,ATP1A2,KSR1,CACNA1G,CFAP410,RUNX1T1,CDH18,CDO1,SULT4A1,ABI3BP,NCOR2,SNCAIP,INTS1,CTIF,DBT,SPOCK3,MRNIP,KCNMB2,APC2,CEND1,KHDRBS3,FUT9,HBS1L,SIGLEC8,DISC1,ATP8A2,GCNT2,ADAM28,GFER,RUNDC3A,GNAO1,GPER1,ADAMTS13,GRM1,ATXN2L,HLF,KCND3,LSS,TAGLN3,MX1,PFKFB2,PIK3CD,PLTP,PILRA,MINDY2,PRKCB,FAM120C,FAT4,ZMAT4,KLHL11,ZNF821,NLGN1,SLC1A7,SLC11A1,ZNF423,SPTB,RBM26,WSCD1,SZT2,CRTC1,TPM3,FLRT2" Drug 3134_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ACTN1,CDC42BPA,ANK3,SEMA4G,ALDH4A1,CDK5R1,CDK5R2,CACNB2,CAPN3,LHX2,WHRN,CREM,NCOR2,PDE4DIP,CTNND2,RUSC2,SPOCK3,SV2A,LRRC23,EPHB1,ETV1,FGFR1,C1orf61,PDLIM5,GPR153,FYB1,ALDH1L1,POLL,KCNMB4,GPR22,GRM8,PADI2,HTR2A,TJAP1,ITIH2,KCNN1,MAP4,MOBP,TAGLN3,NCAM1,NNAT,PDGFRA,PFKFB2,EPB41L4B,POLG,PTPRN2,TTLL7,FAM102A,SLC1A7,SNCA,ATP10B,TBCEL,CUX2,RPGRIP1L,SZT2,CRTC1,AHCYL2,THRA,TMOD1,VIPR2,ADAMTS9,PAK5" Drug 4236_UP Gabazine [105538-73-6]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ACTN2,NME5,MRTFA,PKP4,MARCH3,BMP7,SYNJ1,LDLRAD4,BTRC,CACNB2,HAP1,RUNX1T1,CHRNA4,ARHGAP22,QKI,HOMER3,HAPLN1,PDE4DIP,CNTNAP2,MAML1,DAPK3,SRGAP3,EXOG,COQ7,EFS,ZNF391,ETV1,PIPOX,PTK2B,FGFR1,DCTN2,DLL3,RAB30,STON1,GRIK5,CACFD1,ATXN2L,HTR2A,MAN2A2,TM6SF1,MMP16,LYRM9,NPTX1,NTRK3,PDE2A,PDE4A,PDPK1,PLXNB1,PPP5C,MAPK10,C1orf54,GAL3ST4,PKNOX2,ZNF334,CXXC4,TNIK,ZC3H13,ADGRL3,AP4E1,ICAM5,LAT2,DPF3" Drug 5047_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ASIC1,ADCY2,PLA2G6,APAF1,APC,MARK4,BMP7,GYG2,CFAP410,ADGRG1,CHN2,KIAA1549L,NMT2,DNAJB5,FAM131B,DAPK1,DUSP9,ABCC9,SEMA3D,SIDT2,COQ7,SPEG,ETV1,ST3GAL6,FGF1,PDLIM5,PRELID3A,GNG3,GPR22,GPER1,GRIK5,GRM7,ATXN2L,IRF8,IL6R,LMO2,MATN3,KITLG,CNOT4,NPTX1,NPTX2,PCBP3,NTRK2,RETREG1,PLCD1,PRKAR1B,PTPRN2,MARCH1,PID1,RAD52,RGS10,RPS20,SH3BP2,KIF13A,KDM4B,ZHX3,PHLDB1,TBCEL,CRTC1,CHST5,CA14,SEMA3B" Drug 3554_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ASPHD1,AMPD2,OGT,APBB2,CDC14B,MARK4,ALDH4A1,C5,RAB29,CA12,CACNB2,AP4M1,VAX2,SULT4A1,NCOR1,PDE4DIP,EDRF1,MAML1,JAKMIP2,DMPK,FCF1,SIDT2,ING4,EML1,ANKMY1,TPK1,GNG4,GPR37,GRB10,NR3C1,KCNF1,LIG4,MAP4,MIA2,LYRM9,PCDH9,PPP3CC,ELOVL2,RAD52,GSTCD,ZNF821,FBXO11,WDR47,SLC6A8,CDK5RAP2,LIMCH1,RBM34,SP2,UHRF1BP1L,CEP68,DIP2A,EXOC7,DNMBP,SMG6,TRIM2,ZMYND8,HIRA,VGF,MICAL1,LMF1,ZBTB14,AAAS" Drug 7227_UP Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "KIAA1324,SYT13,AMPD3,BIN1,APAF1,ARHGDIG,AZGP1,NRP2,CFLAR,SCAPER,CA4,USP2,ARHGEF1,ADGRG1,PLEKHB1,STOML1,RABGAP1L,EFNB3,SORBS3,C3orf18,BAIAP2,ANKFY1,OGA,ERAP1,SRCAP,GNAL,LPAR4,GPR37,SPACA9,GRIK5,GRM8,MAP4,MGAT3,AFDN,MYO7A,ZNF862,NF1,NFYA,CNOT4,NUMA1,LRP12,MINDY2,PPP5C,ELOVL2,PTPRO,ATG16L1,KHDRBS2,GSTCD,KCNIP1,SCN2B,ZFP30,FAM102A,SNCA,ZNF415,PHLDB1,TBL1X,TMEM151B,PSD3,WIPF1,ST7,SSPN,JPH3" Drug 3801_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ASPHD1,ADCY2,ALK,SEMA7A,NRP2,CDC42,ARHGAP33,CACNA2D2,FOXN3,TPP1,ARMC8,CREB5,CNTNAP2,RIMS2,ATN1,ECM2,SUGP2,MRNIP,PLEKHO1,ATP8A1,FGF1,FGFR1,SRCAP,C1QL1,GRIK5,ATXN2L,ICA1,TJAP1,ITGA7,ITIH2,LAMA2,MAP2,MAPT,NUMA1,ODF2,PBX1,PENK,PIK3R1,RAD52,ZCWPW1,ZNF671,RASA3,ST6GAL1,NLGN1,SLC4A3,RPH3A,SHANK2,TSNAXIP1,CAND2,IQSEC2,COLGALT2,THSD1,KAZN,KIAA1107,TBCEL,RPGRIP1L,TNS1,TRIO,VAV2,XRCC4,REEP1,MVB12B" Drug 1522_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "DPF1,ABHD6,ADORA1,CDK13,MARK4,ATP1A3,SLC4A4,SYNJ2,SCAPER,CACNA1A,CACNG1,ARHGAP33,CACNA2D2,FOXN3,GREB1,DCAF4,MAGI2,DRP2,MBNL2,PLXNC1,EIF4G2,VPS13B,ERCC2,DLC1,CAMSAP1,GPR153,C1QL1,MSL3,PRUNE2,KLF12,TJAP1,ITIH2,KCNK2,MOBP,CD200,GIT1,NUMA1,CDK14,PIK3CD,PLCD1,ZSCAN2,RAD52,ZMAT4,EMID1,RYR1,ITSN1,DOCK10,SLC1A7,SLC11A1,BTBD7,SLC22A4,ZCCHC24,PEG10,SPART,VPS13A,POPDC3,TCF4,ZEB1,HIRA,VAV2,VSNL1,EMSY" Drug 2173_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "PRX,ALDH4A1,USP2,NEURL1,REPS2,KCNAB3,CHI3L2,CHM,CPNE6,DNAJB5,EDRF1,DYRK1A,SEZ6L2,MBNL2,VPS13B,RASGRP2,STX2,ETV1,CEND1,FHL1,FLT1,CAMKK2,GAA,GABRA2,FERMT2,MAP4,MAPT,CD200,MSR1,NINJ2,NOVA2,POU3F2,POU6F1,PPARA,CEP41,PKIA,MAPK8,RELN,FAM120C,PID1,RGS12,ZFHX4,FOXRED2,FERMT1,CPEB3,SLC8A2,IQSEC2,CLSTN2,SS18,MAPK8IP3,TAC3,TACR1,CAMSAP2,SIN3B,ZFPM2,TMPRSS5,FLRT1,KLC2,SLC17A7,KCNAB1,PAK5,PHTF2" Drug 4661_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "AGT,NME5,BIN1,APBB2,SYNGR3,PLEKHB1,PLAA,RAB26,CREM,SH2B1,VCAN,CTNND2,ARHGAP32,TOX,KIAA0513,CTIF,KIAA0753,SMG7,EXOG,DTNA,EDN1,EDNRA,EFCAB2,FYB1,ZNF44,GAD1,ERAP1,GLUL,GUCY1B1,TJAP1,KIF2A,KIF5C,MAPT,NDUFA5,CNOT4,LRP12,PPARA,GON4L,TMEM231,RAB3A,RGS10,TTLL7,ROM1,MCMBP,RPS6KA2,ATXN7,SUPT20H,FRMPD1,SLC14A1,TSNAXIP1,KDM4C,UNC5B,SYT11,CRTC1,TIAM1,UBTF,WNT7A,XRCC4,WNK1,KCNAB1,PHTF2,NUP214" Drug 5254_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ARID1A,ADORA1,KIDINS220,LTBP4,N4BP2L1,KSR1,BAIAP3,CACNG1,CD86,ARHGEF1,CLCN4,STOML1,TENM4,CSF1R,VCAN,ARHGEF4,RIMS3,TMCC2,SIDT2,EGR3,EFS,REEP2,CORO2B,ATP8A1,FGFR1,CAMSAP1,AGAP2,SORBS1,PDLIM5,GNAO1,GPER1,KCNMA1,AFDN,NF1,CDK18,PDE1C,ENPP2,TMOD2,RELN,CNNM2,ZDHHC14,RET,KLHDC8A,RPS6KA2,ZFP2,ZNF821,NLGN1,SLC1A7,FAM214B,MYH15,SNCA,ARHGAP26,IQSEC2,SYT11,ARC,DMXL2,DNAH7,TMEM121,CRB1,TK2,ZNF154,PARP11" Drug 5492_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "AGT,ALK,BEGAIN,CDK10,ALDH7A1,AZGP1,CFLAR,MTMR2,CACNB4,HAP1,CDC42,CDH18,CNTNAP2,EDRF1,HP1BP3,DMD,MBNL2,DMTN,LRRC23,OLFM1,BAIAP2,IQCG,GABRA2,GLS,GNAS,GPM6A,SYNPO,IFI16,KCNJ5,KCNN2,SMAD1,MATK,AFF1,AFDN,MSR1,MYT1,NFYA,P2RY1,PLCD1,PLEC,LRP12,PTCH1,FAM120C,CCDC40,ZDHHC14,SCG5,SLC6A8,ELMO2,PDZD2,SOX2,NMNAT2,CLSTN2,AJAP1,EXOC7,SMG6,TMOD1,PARD3,TNS1,SSBP2,TTPA,KCNK12,KCNAB1" Drug 4811_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ACTN2,NME5,PLA2G6,AMPD3,ATP2B3,CACNA1G,BAIAP3,CFAP410,CACNB2,CALB2,RUNX1T1,CBFA2T2,NEURL1,CDH8,CLGN,EPS15L1,ARHGEF6,NECTIN3,CRY2,CTH,DCAF4,SPOCK3,HS3ST2,DRD1,DTNB,SEMA3D,EFNA3,EFNB3,EIF4G2,NRN1,TMEM8B,GPER1,ADAMTS13,NR3C1,GRM1,ICA1,ITIH2,KCNB1,MAOB,NF1,NPTX1,P2RY1,PDE4D,CYTL1,PIK3CD,NLE1,MBOAT7,PTHLH,UEVLD,CPEB3,SLC1A2,PKNOX2,KDM4C,MLC1,PSD3,AP4E1,GPR161,CABIN1,FAM155A,VIPR2,ZNF24,NT5M" Drug 5993_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "SEMA6A,ANK2,ARHGDIG,RGS20,ATP1A3,CADM3,CACNB2,HAP1,CBFA2T2,NEURL1,CACNA2D2,RCBTB2,TCEAL2,MAML1,DAPK3,DCC,CNIH3,VPS13B,COQ7,MTSS1L,KCNMB2,REEP2,ATP8A1,FGF1,FHL1,FYB1,INPP5K,SRCAP,PCDH17,GRIK5,GRM8,RASSF8,KCNJ3,MDM4,MYT1,PDE3B,ENPP2,RETREG1,PPP2R2B,MAPK8,ZSCAN2,EMID1,SEMA6D,RASA3,RPH3A,SLC11A1,SHANK2,SLC12A4,COA1,SMARCD3,LIMCH1,SNCA,KIF21B,INKA2,POPDC3,RPGRIP1L,TRIO,VGF,LAT2,SCG2,KCNAB1,ITM2C" Drug 440_DN "W-13, hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "BRAP,AMT,CDC42BPA,GAS7,DGKD,SHTN1,PDXK,BACH1,SLC25A14,ENTPD6,CDH18,LHX2,NMT2,STOML1,TMEM59L,NIPBL,AATK,ARHGEF10,DZIP3,USP6NL,RIMS3,EXOG,FCF1,RBM12,RGS17,STX2,SCML2,FGFR3,PRKAG2,GAB1,MALT1,RUNDC3A,ATF7,LILRA2,BTN2A1,RNFT2,ARHGAP19,MAPT,ADAM22,MYT1,NACA,NELL2,NPPA,NPR2,ENPP2,PLCD1,POLG,MAPK8,SMARCE1,SON,SPART,SYN1,TACC1,AHCYL2,TNS1,SEZ6L,TRIO,HIRA,PDIA2,WIPF1,MPPE1,EPM2A" Drug 7489_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "NDRG2,ADORA2A,C1QTNF3,SEMA6A,APBB2,APOC1,CDK13,ADGRB1,BMP7,SYNJ2,CDH10,CHN2,ZFYVE9,NMT2,VAX2,CNTN1,WHRN,BAG4,NRG2,PDE4DIP,CTIF,TMCC2,TOM1,EGFR,MBNL2,SORBS3,STX2,KIAA1109,FLNC,GLS,GPR19,RASSF8,HNMT,TJAP1,IL6ST,ITPKB,KCND3,KCNH2,KIT,NF1,CNOT4,PAK3,PIK3CD,PLCD1,SLC25A23,LRRN3,MAPK7,BCAN,SOX15,EMC1,KDM4C,STX1A,ASTN2,WSCD1,PCDHA5,AHCYL2,SLC44A1,TRIO,TUBB1,UCHL1,FLRT2,KCNAB1" Drug 7262_UP Alfadolone acetate [23930-37-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ADCY6,AMPD3,LGR5,ARRB2,CCDC181,RUNX1T1,LRRFIP1,CRLF1,RCBTB2,SOCS6,LHX2,RAB28,NRXN3,DNAJB5,COL9A3,RCHY1,CSF1,ARHGEF10,ARNT2,FAM13A,MTSS1L,KIAA1109,COPS8,TDRKH,GPR37,GRM1,GUCY1B1,MUM1,KLF12,ICA1,SHISAL1,INPP5B,KCND3,MIA2,MITF,MKLN1,NF1,NPTX1,PBX1,PDE4D,PDGFRA,PIK3R1,SLC25A23,PMS2,PRKAB2,RAD52,KCTD17,RPS6KA2,SLC14A1,SPART,SYP,WWC1,ZEB1,ARHGEF12,R3HDM1,PARD3,CABIN1,TNS1,ZMYND8,ZNF189,SCG2,SEMA3B" Drug 4689_UP Riluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "RALGAPA1,AMPD3,KCNAB2,FAM131A,PPP4R4,PLA2G4C,BRINP2,NRP2,CFLAR,BAIAP3,CLCN4,FAM149A,ENTPD4,FAM169A,CTH,GIT2,SIDT2,DMTN,CEND1,KIAA1109,FGFR1,GABRA2,GALC,RND1,GNAS,GRB10,GRIK5,CACFD1,NR3C1,GRM8,C2orf72,JAK2,VWA5A,MID1,MN1,MYO7A,NFYA,NPR2,PALM,PFKFB2,SERPINI1,STRN3,LRP12,LRRN3,RGS10,RGS12,GSTCD,CCDC25,FRMPD1,SMARCD3,SNCA,ZC3H13,ZBTB43,TROVE2,ST5,PCDHA6,PCDHA5,AMACR,ZFP37,PRDM2,NAV2,NLRP3" Drug 5477_UP "Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ADORA1,AP2A2,KIAA1324,ATP1A3,ALDH7A1,CFLAR,CACNA1I,BAIAP3,CFAP410,ARHGAP33,CPS1,TOX,DAPK1,SGK2,HIPK3,ELAVL2,HSD17B14,LRRC23,RASGRP2,ERBB4,ZNF589,FGFR1,BAIAP2,MALT1,GLS,STON1,GRM2,GUCY1B1,LIG4,VWA5A,MMP16,ADAM22,NELL2,NNAT,NPY,MINDY2,PTH1R,ELOVL2,KCTD17,RPS6KA2,KCNIP2,BCAN,SLA,ELMO2,ZKSCAN3,PDZD2,ZCCHC24,IZUMO4,ZC3H13,EPB41L3,SS18,AJAP1,SEMA4A,SYNE1,AP4E1,SEZ6L,CHST5,ZMYND8,ZKSCAN5,PRDM2,EVI5,FAM13C" Drug 6800_UP Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ADCY6,TRMT9B,KCNAB2,PRX,ARRB2,ALDH7A1,CADM3,CFLAR,CACNB4,HIP1R,CBARP,DNAJB5,CNTN1,RGS6,PDE4DIP,DAPK3,SPOCK2,DBN1,ARMCX2,JAKMIP2,VPS13B,OLFM1,FHL1,PDLIM5,FYN,GAB1,GFER,GLI2,GPR19,GRM1,INPP5B,JAK2,KCNJ3,MID1,ZNF862,PAX6,PDE1C,PDE4A,NLE1,PRKAR1B,MAPK8,NLGN1,SLC11A1,SHANK2,SLC12A4,CDK5RAP2,SMARCD3,ZNF415,WDTC1,TROVE2,SYT5,PSD3,THBS4,TNS1,FAM155A,UBE3A,PLPPR2,ZNF711,EVI5,ITM2C,MPPE1,SSPN" Drug 4601_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ABAT,ASPHD1,C1QTNF3,GAS7,DNAH17,ATP2B3,MTMR3,CACNA1I,BTRC,CACNA2D1,KRIT1,ARHGEF2,CLCN4,CPS1,CREM,CRY2,PDE4DIP,SPOCK2,GIT2,C2CD2L,SMG7,PARD6A,ATN1,DSCAM,DTNA,SRPK3,DMTN,MTSS1L,ETV1,REEP2,KIAA1109,TRMO,LYVE1,TDRKH,ATXN2L,ITGA7,VWA5A,MIA2,NPTX1,P2RY1,PDE4B,SPATA6,PKN2,VPS13C,PTPRB,PTPRN2,TMEM231,ACSS3,RGS7,FBXW7,SH3BP2,FBXO11,SLC20A2,SNCA,UNC5B,SS18,SYN2,TIMP4,HIRA,VAV2,MVB12B,DPF3" Drug 2557_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ACTN2,PKP4,PPP4R4,MPDZ,KSR1,MYRF,THSD7A,SLC16A4,CDH2,TAOK2,ZFYVE9,CLCN4,STOML1,HOMER3,CNTN1,COL9A3,ABI3BP,CSNK1E,PDE4DIP,SLITRK5,USP6NL,EDRF1,DGKG,MFAP3L,EDNRA,RASGRP2,RRAGB,OLFM1,DCTN2,MYOZ2,ADAM28,GPD2,PRUNE2,GPM6B,GPR19,GPER1,KLF12,TJAP1,KPNA5,MAPT,MOBP,TAGLN3,NUMA1,PFKFB4,PLEC,PLP1,PKN2,PTK2,RET,RASA3,SLC11A1,SNCA,TNIK,RAP1GAP2,ZC4H2,TRIM2,PSD3,CRTC1,AHCYL2,SLC17A6,CAMK1G,GAN" Drug 6105_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "MRTFA,AMPD3,GAS7,APP,ARHGDIG,PDE8B,DNAH17,NCOA1,CADM3,MTMR3,SGCE,CA4,CACNA1D,CACNA2D2,AKAP7,RCHY1,CSF1R,PDE4DIP,GREB1,EGFR,MBNL2,ING4,LRRC23,FAM198B,BAIAP2,GLYR1,GNAS,GPER1,NR3C1,GRM1,JAK2,IPO5,ADAM22,NF1,GPR85,MAPK8,GRAMD1C,ZSCAN2,ROM1,WLS,SEMA6D,RASA3,FRMPD1,LIMS2,SMARCD3,MAPKBP1,SNCA,KIF13A,ZHX3,IQSEC2,VAMP1,PLCB1,TBCEL,IQCE,DOCK9,TK2,ZKSCAN5,FAM155A,WIPF1,ZIC3,ZNF45,SENP7" Drug 4627_DN Altretamine [654-05-6]; Down 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "TRMT9B,AMPD3,PDE8B,ADGRB2,LDLRAD4,B4GALT6,SLC4A8,DCAF4,SGSM2,TRAPPC9,ATN1,DTNB,FEM1B,MBNL2,MRNIP,MTSS1L,STX2,FOXG1,GCNT2,ARFIP1,ZNF276,GNAL,GPM6B,GPR17,GPR19,GRM1,TJAP1,LIG4,MAPT,MGAT3,NDP,NEK1,NEUROD1,NOVA1,NUMA1,OPCML,PDE1C,PDE4B,SYTL2,PTPRB,FAM120C,ATXN2,ATXN7,ZFP30,FRMPD1,SLN,MYH15,TMCC1,TSNAXIP1,ARHGAP26,SPTAN1,JMJD6,EXOC7,ARHGEF12,CRTC1,THRA,TK2,BHLHB9,RIMBP2,AMACR,CADM1,KCNAB1" Drug 4113_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "SYN3,NDRG2,KLRC4,N4BP2L1,CACNA2D1,CACNG1,CBFA2T2,CDH10,CHRNB2,FAM149A,WHRN,COL9A3,TCEAL2,CRY2,AATK,RIMS2,SPOCK3,ATN1,HIPK3,PLXNC1,RCAN2,EPHB1,PTK2B,GAD1,ARPP21,GFER,RND1,NR3C1,GUCY1A1,PTGDR2,VSIG4,ICA1,LMO1,VWA5A,MSR1,SLCO1C1,NNAT,NPTX1,OGG1,OMG,ENPP2,PFKFB2,CDK14,CEP41,RAB3IL1,KLHDC8A,RPS6KA2,SYNDIG1,SH3BP2,PPP1R9A,DOCK10,SLC2A5,FAM214B,SLC11A1,SMARCD3,LIMCH1,INKA2,KIAA1107,CHST5,ZIC3,SLC17A7,ITM2C" Drug 3175_DN Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ALCAM,APBB2,APC,FAM131A,MARK4,NCOA1,ATP6V0A1,SCAPER,MTMR2,MAGI1,TAOK2,CDC42BPB,AKAP12,CRY2,PDE4DIP,SDC3,GREB1,KBTBD11,TOM1,SORBS3,ENO2,DMTN,ERBB2,FECH,FGFR1,FHL1,GAB1,SYT17,DISC1,MALT1,POLL,GPD2,CNTRL,SPACA9,GRM1,BTN2A1,ITPKB,KCNH2,CAMKV,PMP22,PRKACB,MAPK7,RIPOR1,CEP97,RGS3,ZNF821,SLC1A7,BTBD7,ZHX3,ZBTB43,NCDN,STX1A,MTCL1,TRIM2,DOCK9,ZNF34,RBFOX2,ZKSCAN5,HIRA,REEP1,HPS4,EPM2A" Drug 5770_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "ADD2,SEMA6A,BEGAIN,TRMT9B,EPB41L5,APOC1,RGS11,CFLAR,BMP7,CACNA1I,MYRF,CDK5R2,CDH8,MAGI1,TAOK2,ARHGAP22,PICK1,AKAP5,FRMPD4,SPOCK2,DCT,EDN1,CELSR3,MBNL2,ING4,LRRC23,FGF1,HPCAL4,OGA,ZNF44,LILRA2,LPAR4,GRIN1,GRM1,GUCY1A2,IL12A,KCND1,KCND3,LMO1,LMO2,MATK,ADAM22,TAGLN3,MYT1,PCBP3,MAPK8,MAPK10,VPS13C,RET,ASIC4,ZNF821,SLCO1A2,OGDHL,HECW1,SSTR2,PCDHA6,AP4E1,TLR4,TNS1,TRH,SLC17A7,KCNAB1" Drug 6079_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "DPF1,KIDINS220,BIN1,ANK1,APAF1,GAS7,ASPA,SLC2A11,CHM,SLC24A2,CLTB,WHRN,NCOR2,SEC14L5,ELMO1,ST8SIA3,EFNB3,RASGRP2,APC2,FLNC,GPR153,DLL3,OGA,FYB1,GABRA2,ZNF44,DISC1,SRCAP,LYVE1,GPR22,GRIN1,SOX21,C2orf72,KCND3,KCNH1,KCNH2,KCNN1,LAMA2,LIFR,MAG,MGAT3,CD200,P2RY1,PFKFB2,PPP5C,CEP41,PRKCB,RELN,RYR1,RPH3A,SLC2A5,SLCO1A2,SOX10,DOK5,COLGALT2,CRTC1,TK2,R3HDM1,TUB,LAT2,STMN4,ADAMTS9" Drug 5446_UP Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.93E-08 1.44E-03 1.64E-06 1.86E-05 62 198 "DPF1,RALGAPA1,ASIC2,ADORA1,ADORA2A,KIAA1324,LTBP4,BIN1,APAF1,APC,GAS7,ATP2B2,CACNA1D,HAP1,CAMK2B,USP2,ARHGAP33,CLCN4,TPP1,DCAF4,RIMS3,JAKMIP2,HIPK3,BAIAP2,HPCAL4,FOXG1,NR3C1,GSTM5,PTGDR2,KLF12,HNMT,ITPKB,KCNJ4,KIT,MAP4,MMP16,GIT1,NEFM,PDGFRA,TMOD2,PLTP,GDPD2,RASGRF1,RGS12,KCNIP1,SEMA6D,SELL,CNKSR2,SLC1A2,SLCO1A2,PDZD2,WDTC1,SOX2,DOK5,ZHX3,VAMP1,DMXL2,ZEB1,SLC30A3,WNK1,PLSCR4,NUP214" Drug CID000003538 GYKI 52466 Stitch 3.15E-08 1.54E-03 1.76E-06 2.00E-05 27 58 "CA4,CSF1R,DLG4,ABCC9,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,BCO1,MAPK10,PTCH1,SLC1A2,JMJD6,NUP214" Drug 4546_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "C1QTNF3,MRTFA,AMH,AMT,EPB41L5,GAS7,CDK10,ATP2B2,N4BP2L1,ATP6V0A1,FUBP1,MYRF,KALRN,HAP1,ARHGEF2,ARHGAP33,SLC4A7,NRG2,VCAN,SPOCK2,MFAP3L,RABGAP1L,DLG4,TRAPPC9,EDN1,SIDT2,ELN,RCAN2,ETV1,ZNF589,KIAA1109,AFF2,GAB1,ERAP1,ADAM28,RND1,GLI2,GNG4,PTGDR2,ATXN2L,KLF12,ICA1,KCNJ4,LIFR,LMO2,NF1,PDE4D,PENK,PPARA,CCDC40,RGS12,ASAP3,PKNOX2,SNCA,SYT11,COBL,ADGRL3,TRPC3,VGF,KCNAB1,MVB12B" Drug 6555_DN Prostaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "AMT,ANK3,APOC1,PPFIA3,RGS20,ARRB2,MARCH3,ASPH,MPDZ,CLCN3,KIAA1549L,NCOR2,AATK,MICAL2,CNTNAP2,SPOCK3,RCAN1,FCF1,CNNM1,LRRC23,ZNF589,FGFR1,PDLIM5,CSPG5,TRAF3IP2,B4GALNT1,GCNT2,ARFIP1,HNMT,IL6ST,MT1M,NFIX,NPR2,PPP5C,PTPRN2,RFX5,RGS7,RGS10,TTLL7,RPS6KA2,RXRA,SH3BP2,FNDC3A,SLN,DOP1A,CAND2,BEX1,TROVE2,THSD1,SS18,JMJD6,COBL,ASTN2,TCF7L2,ZNF34,TMOD1,TRPC1,MAP3K12,UBE3B,KAT6A,RNF146" Drug 2965_UP Iopanoic acid [96-83-3]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "MTUS1,PLA2G6,ADGRF5,CDC42BPA,GAS7,MARK4,BMP7,CACNA1I,BAIAP3,LDLRAD4,CACNA1A,NEURL1,CDH8,CDO1,TAOK2,CLCN4,NMT2,HOMER3,SH2B1,CSF1,CSF3R,ARHGEF10,PDE4DIP,PPP1R16B,KIAA0513,ZNF337,DBT,CELSR3,C3orf18,POLL,GSTM5,MAN1B1,KCND1,MAP4,AFDN,CNOT4,NRCAM,CCSER2,PLEC,POU6F1,PTAFR,TCP11L1,EPN2,SLC11A1,BTBD7,WDTC1,TSNAXIP1,SPTAN1,SPART,CLSTN2,PDLIM2,OBSL1,TNS2,CRTC1,TEK,TNS1,CDK20,FLRT1,VIPR2,URM1,MPPE1" Drug 2863_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "RALGAPA1,NDRG2,ADRA1D,BEGAIN,AMPD3,BIN1,KCNAB2,GAS7,BRINP2,ATM,CFLAR,GYG2,CA4,CAMK2B,SLC16A4,CHM,AKAP6,RUSC2,DLG2,DNAH9,EDN1,EGFR,ELN,ERCC2,ANKMY1,REEP2,FGF1,GAB1,SRCAP,RND1,GLS,GPM6B,GPER1,NR3C1,GSTM5,HLF,KCNQ3,ADAM22,NELL2,CNOT4,NPTX2,NUMA1,CDIP1,PPARA,C1orf54,KCTD17,SYNDIG1,BTBD7,LIMCH1,KDM4B,DOP1A,TSNAXIP1,IQSEC2,ABCC8,ARC,TCF7L2,PARD3,TPM3,ZMYND8,KCNAB1,ITM2C" Drug 5752_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "ADD2,APBB1,N4BP2L1,SYNJ1,GYG2,CDK5R2,PLEKHB1,KIAA1549L,TPP1,AKAP12,CRMP1,ABCG1,PHYHIP,DSCAM,DTNA,ECM2,EGFR,PLXNC1,ING4,FGFR1,HPCAL4,SEMA4D,GABRA2,ZNF44,SRCAP,RND1,COPS8,GNAO1,GPM6A,GRIA4,SPACA9,ADAMTS6,HRH3,KCNJ4,KIT,ADAM22,OMG,PDE4D,PPP5C,MAPK10,PTN,ZSCAN32,ACSS3,NEK11,TCP11L1,SEMA6D,SUPT20H,NLGN1,PPP4R3A,SLC11A1,FAIM2,RBM34,SPTB,IQSEC2,SYN2,MCF2L,ZIC3,SLC30A3,NT5M,NAV2,MVB12B" Drug 2789_UP Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "ADORA1,MRTFA,TRMT9B,AMPD3,PLA2G4C,ST3GAL5,BAIAP3,PTBP2,CBFA2T2,TAOK2,WHRN,RCHY1,NECTIN3,TENM4,ATRNL1,RIMS2,HSD17B14,KCNMB2,REEP2,FAM198B,PTK2B,FGF12,FGFR1,DPYSL4,GAB1,HBS1L,ERAP1,RND1,MSL3,GPER1,GRIK5,GSTM5,ICA1,MAP4,MAPT,BCO1,NELL2,PFKFB2,TNPO2,PRKCB,MAPK7,MAPK8,GRAMD1C,PTX3,TRIM68,RNASEL,TCP11L1,SYBU,EPN2,SLC6A8,ZCCHC24,NPAS3,MAPK8IP3,TTBK2,VAMP1,EXOC7,SZT2,CABIN1,ZMYND8,VAV2,KAT6A" Drug 6021_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.19E-08 1.56E-03 1.76E-06 2.01E-05 61 194 "NDRG2,AK2,MRTFA,AMH,CDC42BPA,ARRB1,DNAH17,ATM,ALDH7A1,ADAM23,CFLAR,KSR1,GYG2,ARHGAP33,ADGRG1,FADS2,QKI,CNTNAP2,SDC3,RIMS3,CDON,DRD1,EFNA3,KAT8,IQCG,FAM49B,GAD1,DISC1,GLYR1,GRM8,ITPKB,KCNC1,MITF,NDUFA5,NF1,PDE3B,MINDY2,SAMD9,RAB3IL1,ATG16L1,MRAS,ITSN1,PREX2,EPN2,SLC6A8,BTBD7,CXXC4,COA1,SOX2,TROVE2,EXOC7,PSD3,CRTC1,PCDHA5,TMOD1,VAV1,XRCC4,ZFP37,GDPD5,KCNAB1,SENP7" Drug CID000003838 KN-62 Stitch 3.43E-08 1.68E-03 1.90E-06 2.16E-05 69 230 "ADRA1B,SLC4A4,ALDH7A1,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB2,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,LRBA,CHRM1,MYL6B,CALY,HDAC9,HDAC4,DBI,MYEF2,EDN1,EDNRA,PTK2B,CAMKK2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,MYLK2,ITGAM,JAK1,KCND3,MYL3,NPPA,P2RX7,P2RY1,PDCD2,PENK,CAMKV,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK8,PTK2,RYR3,FNDC3A,SLCO1A2,SNAP25,STAU1,ARC,SYN2,CABIN1,TRH,VIPR2,P2RY12,PLD4,CAMK1G,NUP214" Drug 6979_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.46E-08 1.69E-03 1.90E-06 2.17E-05 60 190 "BIN1,GAS7,BCAS1,BAIAP3,CCKBR,CHM,CRY2,CTNND2,DMPK,DNAJB6,ST8SIA3,MBNL2,EIF5,COQ7,LRRC23,RASGRP2,SPEG,FAM198B,ANKFY1,CNTRL,SPACA9,CACFD1,INPP5B,KCNJ5,KCNK2,MAP4,MBD1,KITLG,NAP1L2,NCAM1,NF1,PALM,PDE3B,PRKCB,KLK6,SAMD9,PTPRN2,FAM184A,PAQR6,HSPA4L,SH3BGR,BCAN,NLGN1,PREX2,UNC5B,CLSTN2,SEMA4A,WSCD1,PCDHA6,TEX15,TPM1,FAM155A,VIPR2,VLDLR,LAT2,WNT7A,XRCC4,ZNF74,SSPN,FXR1" Drug 7145_DN Nocodazole [31430-18-9]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.46E-08 1.69E-03 1.90E-06 2.17E-05 60 190 "APBB2,APP,BCL2L2,SYNJ2,REPS2,TBRG4,RCBTB2,KIAA1549L,AKAP7,TENM4,USP6NL,KIAA0513,KIAA0753,KLHL3,RHOBTB1,DLG3,EGFR,STX2,VPS26C,NBEA,TACC2,FAM49B,GCNT2,GNAS,GUCY1B1,HAS2,ITPKB,TAGLN3,NEK1,PCDH9,PDGFRA,SERPINI1,PIK3R1,CCSER2,PPP2R5C,SYTL2,RAB3A,PID1,ATG16L1,ATXN7,ABLIM3,PEX26,ZKSCAN3,TNIK,SPATA7,CAND2,ARHGAP26,SS18,TTBK2,RGL1,ARHGEF9,SIN3B,TCF7L2,HEY1,SSBP2,NPDC1,XRCC4,ZBTB14,TRIM9,KAT6A" Drug 2375_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.46E-08 1.69E-03 1.90E-06 2.17E-05 60 190 "NDRG2,ADD3,SLC12A5,ADORA1,APBB2,ATP2B2,CADM3,ST3GAL5,MYRF,CFAP410,CAMK2B,CHN2,JAM2,CRMP1,ABCG1,PDE4DIP,DZIP3,PPP1R16B,CTNND1,CX3CR1,RIMS3,DNAJC6,GSDME,EFNA3,EGFR,ENO2,EPB41L1,ETV1,PIPOX,F3,FGFR1,GAB1,GABRA5,INPP5K,GRIN1,SLC2A6,DIPK1A,ITGAM,KIF5C,VWA5A,MEF2C,NCAM1,NF1,NRGN,SERPINI1,PLCD1,PMP22,KCTD17,FAM214B,ZCCHC24,RGL1,STXBP1,DNMBP,CAMSAP2,TPM1,TRH,BEST1,TRIM9,REEP1,EVI5" Drug 1072_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 3.50E-08 1.72E-03 1.92E-06 2.18E-05 57 177 "ADD3,ALAD,ARNTL,ST3GAL5,CBFA2T2,AKAP12,CTH,RUBCN,KIAA0513,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,KIF3A,RNFT2,PADI2,KIF5C,MITF,MXI1,NEK1,PCDH9,SERPINI1,PRPH,PTPN13,SGK1,SH3BGR,SH3GL3,PPM1E,WDR47,KDM4B,ZCCHC24,ZBTB43,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,REEP1,SLC17A7" Drug CID000077802 3-chlorobenzylamine Stitch 3.55E-08 1.74E-03 1.92E-06 2.18E-05 36 91 "SYT13,DOC2A,C5,BSN,CACNA1B,CACNA1E,SYT6,RIMS2,SHANK1,RASA4,SYNCRIP,SYT3,GPR37,KCNMA1,SYTL4,PACRG,SYT9,NCF2,SYTL2,RAB3A,RBBP8,RGS4,RGS10,RASA3,RPH3A,RIMS1,SNAP25,SPP1,ERC1,SS18,STX1A,SYT11,VAMP1,SYT1,SYT4,SYT5" Drug 6876_UP BAS 012416453; Up 200; 38uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "RALGAPA1,MTUS1,PLA2G6,AMT,APAF1,APC,EPB41L5,GAS7,ARHGDIG,BSN,KALRN,CBS,CHM,CHRM4,CLU,CNTFR,MICAL2,ARHGEF4,PYGO1,CYBB,DAPK3,CTIF,DBT,MAGI2,PLPPR4,SPOCK3,HIPK3,ZNF549,ETV1,F3,OLFM1,ZMYND11,DISC1,GART,GCNT2,GLYR1,ICA1,IGF1,MDFI,MSR1,NELL2,NF1,PDE2A,PIK3R1,EPN1,FSD1,MINDY2,SAMD9,SYTL2,PTHLH,RAD52,SCN8A,SELL,PEX26,ELMO2,SNCA,SS18,CEP68,PHLDB1,CUX2,UGT8,ZFP37" Drug 1373_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "SEMA6A,PPFIA1,SLC4A4,CADM3,AZGP1,ADGRB2,CA12,CACNA1A,CALB2,CACNA2D2,CHN2,CHRNB2,CNTFR,PCYT1B,SH2B1,CRMP1,TMCC2,DLG3,SGK2,EFNB3,TNK2,SRPK3,ELN,PIPOX,FCGRT,FGFR1,C1orf61,GAP43,GJB1,GLS,GNAO1,GNG4,SPACA9,CACFD1,GRIN2C,GSTM5,AP4S1,TJAP1,KCNF1,MBP,GIT1,SAMD14,NPPA,OMG,KCNK10,DUSP26,SERPINE2,CAMKV,PACSIN1,PPARA,PPP5C,PTH1R,PTN,RNASE1,LGI2,LIMS2,SLC6A11,PHLDB1,DNAH7,ZMYND8,VGF,VIPR2" Drug 6652_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "KLRC4,ADORA3,ANK2,GAS7,PPP4R4,CDK13,CADM3,AZGP1,KSR1,CACNA1D,DNAJB5,NCOR2,PDE4DIP,BRINP1,MYEF2,MFAP3L,SPOCK3,DTNA,RASGRP2,EPHB1,PIPOX,AFF2,RUNDC3A,LILRB4,AP4S1,SOX21,ATXN2L,KLF12,HPSE2,ICA1,KCNB1,KCND3,MSR1,DDX25,NPY,PDE3B,PDE4B,GPR85,PENK,SPATA6,POU6F1,ENOX1,CRTAC1,PNMA8A,CCDC102B,TCP11L1,RXRA,FRMPD1,SLC6A9,SNCA,ATP10B,INKA2,TAC3,KLHL4,DICER1,SEZ6L,TUB,VAV2,KCNAB1,SLC17A6,FAM13C,NLRP3" Drug 4778_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "KIDINS220,AP2A2,MRTFA,AMPD3,AQP4,PPP4R4,ASCL1,BTRC,CA12,CACNA1A,MTMR7,STOML1,AKAP7,CABP1,NOS1AP,CNIH3,DYNC1I1,EFNA3,CAMSAP1,GAB1,LYVE1,GLI2,GRIK5,KCND3,KCNJ5,KCNMA1,KCNN2,MPP2,NTRK2,DUSP26,PURG,PPP1R1A,PRKAR1B,PTN,C1orf54,EMID1,FNDC3A,SLC1A7,PREX2,SLC2A5,PPP4R3A,SLC6A9,CXXC4,SMARCD3,FAIM2,ZC3H13,TROVE2,NXT2,ADGRL3,TBCEL,IQCE,WSCD1,TRIM2,PCDHA5,SLC35G2,TGFBR3,THBS4,TRPC1,VIPR2,MICAL1,ZFP37,MKRN3" Drug 3633_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "DPF1,ADCY2,ADD2,PLA2G6,ANK1,ARHGDIG,CDK13,ATP2B2,N4BP2L1,CACNA1D,CACNA2D1,CALB2,NGB,INA,TCEAL2,NCOR2,ATRNL1,VCAN,DCT,TMCC2,EDIL3,SPEG,APC2,ABCA8,OLFM1,SCARA3,AFF2,KHDRBS3,DENND2A,GFAP,GNAL,LILRA2,ADAMTS13,NR3C1,GRM1,SOX21,GUCY1B1,TJAP1,ITGA7,KIFC3,LAMA2,MGAT3,CD200,NINJ2,PDE4D,GPR85,NECAB2,POU3F2,RGS4,ZNF671,RASA3,FRMPD1,DZIP1,SLC2A5,PHLDB1,THRA,TNS1,TRO,FLRT2,VIPR2,SPHK2,SLC17A7" Drug 6484_UP Urosiol [128-13-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "AK2,ARHGDIG,ASPH,CCDC181,CADM3,N4BP2L1,RIPK1,SYNJ1,CFAP410,CAMK2G,RUNX1T1,TENM4,DCAF4,PHYHIP,DCC,ARMCX2,HP1BP3,RUSC2,HS3ST2,EFNB3,EFS,ST3GAL6,DCTN2,EFCAB2,GCNT2,LYVE1,ZNF276,POLL,GRK4,PCLO,SLC2A6,HAS2,KLF12,HLF,HSF2,INPP5B,MATK,ADAM22,NDUFA5,NHLH1,CDK14,PPP5C,PRKCB,PTAFR,RAB3IL1,KCTD17,MYH14,RYR1,MRAS,PPP4R3A,ELMO2,SNAP25,SNCA,ACSBG1,ASTN2,TRIM2,PSD3,LMF1,NSD2,SLC30A3,SEMA3B,NUP214" Drug 5766_UP Skimmianine [83-95-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADD2,PKP4,SLC4A4,KIF1A,SCAPER,BTRC,CDH8,CHN2,AKAP6,AKAP5,IFFO1,CSNK1E,SUSD5,ARHGEF4,RIMS3,SPOCK2,DBT,ARMCX2,SV2B,SPOCK3,ATN1,EDIL3,EDNRB,EFNB3,ING4,PRUNE2,GRIK5,GRM3,GRM7,IRF8,MARK1,MOBP,MSR1,TAGLN3,MYT1,OPCML,PDE2A,PFKFB4,SPATA6,TNPO2,CEP41,RGS3,RNASE1,TCP11L1,DZIP1,SLC8A2,OGDHL,RIMS1,TNIK,DOK5,SSTR2,MAPK8IP3,SYN2,ICAM5,PRMT8,LAT2,ZNF24,ZNF45,ADAMTS9,KCNAB1,PAK5,NUP214" Drug 2652_UP Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADD2,ADORA1,AP2A2,AGT,SEMA4G,GYG2,CA4,ARHGAP33,TAOK2,ABI3BP,RASSF2,EDNRB,FRY,PLXNC1,EIF4G2,SORBS3,ELAVL3,ACSL4,PTK2B,ZNF589,KIAA1109,FGFR1,SCARA3,C1orf61,IQCG,SEMA4D,ALDH1L1,GCNT2,GFER,GLS,MUM1,ICA1,KCND3,KCNJ5,ADAM22,SAMD14,NDUFA5,NOS1,NPPA,OPCML,PLEC,PLTP,PPP5C,CCDC40,ATG16L1,ZNF493,RGS10,RGS12,SLC11A1,LIMCH1,SOX2,ARHGAP26,IQSEC2,SPART,MAPK8IP3,JMJD6,PLCB1,SYNE1,PCDHGA1,VAV2,CA10,SENP7" Drug 2095_UP Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "MTUS1,PLA2G6,ALAD,RASL11B,ASTN1,NOL4,BAIAP3,RAB28,CRY2,SLITRK5,ARHGAP24,TOX,CTIF,PLPPR4,SPOCK3,SGK2,FCF1,TENM1,RGS17,STX2,ANKMY1,TUBB4A,B4GALNT1,SEPT9,GLI2,GNG3,PRUNE2,LPAR4,KCNB1,TAGLN3,SLCO1C1,NUMA1,OPCML,FA2H,TMEM104,GAL3ST4,RGS3,RGS10,ATXN7,ZFP30,AMBRA1,OGDHL,ZHX3,LHPP,COLGALT2,SUPT5H,ROBO3,MCF2L,PHF24,CHST8,TK2,SEZ6L,TPM1,TRIO,CADM1,UCHL1,LMF1,KCNK12,SPHK2,NT5M,EVI5,DPF3" Drug 5795_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "RALGAPA1,NDRG2,KLRC4,KIDINS220,LTBP4,AMPH,ANK2,ATP2B3,KIF1A,BMP7,CALB2,CHI3L2,SPOCK2,RABGAP1L,ATN1,ECM2,ST8SIA3,EDNRB,PLXNC1,KCNMB2,EZH1,KIAA1109,AGAP2,GATM,NEU3,RAB30,TDRKH,CNTRL,SPACA9,GRIK5,CACFD1,SOX21,IGF1,KCNB1,KCNH2,KHK,KIF5A,VWA5A,MAP2,MSR1,TAGLN3,MYT1,NECAB2,C19orf57,ACSS3,RFX2,TCP11L1,SLC12A4,SNCA,KIF13A,KDM4B,DOK5,RBM26,SSTR2,SYT5,TAC1,TACR1,PHF24,THRA,ZMYND8,VSNL1,KCNAB1" Drug 5053_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ASPHD1,SEMA6A,ALK,AMT,PPFIA4,CDK10,ADAM23,NRP2,BMP7,CAPN3,BRSK2,MAGI1,CACNA2D2,TAOK2,DNAJB5,WHRN,NOS1AP,FRMPD4,DRD1,EDN1,SIDT2,IGSF6,FGFR1,ERGIC3,GAB1,SIGLEC8,RUNDC3A,KCNB1,KIT,KITLG,MOBP,MYT1,NOVA2,SNTG1,PDE4A,PDE4D,ABCB1,MED1,PROX1,DCHS2,PTPRB,PTPRN2,RAD52,RGS4,RGS10,KCTD17,EMID1,RYR1,IL17RB,SUPT20H,NTNG1,ARHGEF40,KIF21B,UNC5B,DDN,ATP10B,DOCK9,SLC44A1,TLR4,VGF,PARP6,SLC17A7" Drug 6291_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ASIC1,MRTFA,APBB2,PPFIA3,ASCL1,ADAM23,NRP2,SCAPER,CALB2,KALRN,RUNX1T1,ARHGEF2,TAOK2,LHX2,FADS2,SLITRK5,EDIL3,EDNRB,PLXNC1,MRNIP,COQ7,DMTN,EZH1,TBR1,TRAF3IP2,DENND2A,ATP8A2,ZNF276,GRIK5,IL6ST,BRINP3,KIFC3,KPNA5,MT1M,NUMA1,PDE3B,STRN3,SNRK,PTPRE,RAB3IL1,RAD52,ENOX1,ARHGEF10L,NEK11,SEMA6D,ZFP30,SH3BP2,PEX26,CCDC88A,SLC9A5,SLN,KIF13A,DOK5,INKA2,MAPK8IP3,CEP68,PHLDB1,ACSBG1,KIAA1107,TRIO,NT5M,NAV3" Drug 6669_UP Benzbromarone [3562-84-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "RALGAPA1,ABAT,ADORA1,CDK13,PTCH2,RASL11B,SLC2A11,BTRC,CALB2,CBS,CCK,SCARB1,CDH10,LARGE1,TAOK2,EPS15L1,NRXN3,TCEAL2,ENTPD4,ABCG1,CNTNAP2,DAPK3,SPOCK2,MFAP3L,SRGAP3,AK5,EDN1,EDN3,HEYL,APC2,RACK1,FLT1,OGA,TPPP,GRM1,GSN,PTGDR2,KLF12,KIT,VWA5A,MDM4,MGAT3,ADAM22,PDGFRA,PFKFB4,FXYD1,TNPO2,PRPH,PTH1R,ZSCAN2,RGS7,ZNF334,SLN,HECW1,ZC3H13,PCDHGB6,CRTC1,CADM1,SLC17A7,KCNAB1,DPF3,JPH3" Drug 5810_UP Diazoxide [364-98-7]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "AGT,C1QTNF1,SEMA4G,KIF1A,CFLAR,CAMK2B,ABCG2,CNTFR,ARMC8,TCEAL2,GIT2,DBT,DNAH9,DRP2,EGFR,PLEKHO1,ZNF589,FYB1,ZMYND11,SIGLEC8,SYT17,SRCAP,GPER1,EML4,CNTRL,GSTM5,RASSF8,IFI16,DIPK1A,KIF2A,KIF5C,KIT,MAPT,TAGLN3,NEK1,CNOT4,ODF2,P2RY1,PC,RC3H2,RAB3IL1,RAD51D,SH3TC2,CCDC25,PRR5L,RPS6KA2,AMBRA1,FBXO11,FNDC3A,RPH3A,KDM4D,SHANK2,MYH15,TMCC1,KDM4C,BEX1,SYP,SLC19A3,VIPR2,LAT2,ZNF74,HPS4" Drug 5522_UP Phensuximide [86-34-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ABR,ADCY6,ADD2,LTBP4,CDK10,CDK13,AZGP1,GYG2,SGCE,CACNG1,CAMK2B,CDO1,CLCN4,QKI,CRMP1,FEZ1,RIMS2,HS3ST2,DTNA,TNK2,MTSS1L,KCNMB2,FOXG1,C1orf61,HBS1L,TMEM8B,POLL,PCLO,KCNB1,KHK,KIF5A,KPNA5,MAOB,KITLG,ADAM22,NF1,PCBP3,NTRK3,PDE3B,PLCD1,PLXNB1,PPP2R2B,GDPD2,SYNDIG1,ELMO2,ZC3H13,BEX1,SYN2,SYP,KAZN,ROBO3,EXOC7,KIAA1107,TNS2,TNS1,ZMYND8,UBTF,PLPPR2,ZNF24,WNK1,NT5M,SLC17A7" Drug 4399_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ASIC2,ACTN2,KIAA1324,C1QTNF1,CDC14B,ASCL1,ADAM23,BAIAP3,CFAP410,RHBDL1,CLDN10,TPP1,RCHY1,CNTNAP2,TOX,DGKG,DAPK1,DBT,SRGAP3,DTNB,HIPK3,EIF4G2,RASGRP2,IGSF6,KIAA1109,FGFR1,GAP43,GRIK5,GRM2,ITIH2,VWA5A,AFDN,MOBP,MYH6,NF1,NNAT,OGG1,OMG,OPRL1,PDE1C,GPR85,TNPO2,POU3F2,CEP41,MAPK8,RAB3IL1,RASGRF1,RFX2,RPS6KA2,SH3GL3,BCAN,SLC1A2,KANSL3,OGDHL,SMARCD3,IZUMO4,SYT5,ATP11A,ICAM5,TNS1,TRPC3,MVB12B" Drug 4810_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADD2,ADORA2A,NME5,KIAA1324,BIN1,APBA2,AQP4,CADM3,N4BP2L1,BAIAP3,CACNA1A,HAP1,CAPN3,RUNX1T1,NEURL1,CDC42,EPS15L1,TMEM59L,COL9A3,NRG2,NCOR2,VCAN,DCT,ELMO1,C2CD2L,ATN1,DTNB,ST8SIA3,ELAVL2,ELN,DLC1,CAMSAP1,AFF2,FYB1,GAD1,GLI2,GRIA4,GRIN2C,GRM1,JAK2,KCNB1,KCNH1,KCNJ5,LMO1,PACRG,MAG,AFDN,NOVA2,NPTX1,PMP2,PACSIN1,PPP5C,SUGCT,MRAS,CNKSR2,SLC11A1,ZC3H13,IQSEC2,MAPK8IP3,AJAP1,GPR161,OSBP2" Drug 4068_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ACTN2,BEGAIN,CDC14B,PPP4R4,ARRB1,CDK5R2,CFAP410,CA12,CACNA2D1,KALRN,CAMK2B,RUNX1T1,ENTPD2,CLCN4,NRXN2,SULT4A1,PCYT1B,HAPLN1,CHD5,PPP1R16B,HEPH,C2CD2L,DSCAM,USH1C,FRY,ING4,HPCAL4,AGAP2,SORBS1,GAP43,SIGLEC8,ADAM28,CACFD1,GRM7,KCNJ4,KCNJ9,MAG,MOBP,MYO7A,NPY,NPTX1,NTRK2,OLR1,PDE2A,ENPP2,PIK3CD,PRKCB,RYR1,SEMA6D,ASAP3,KANSL3,SLCO1A2,DOK5,ARHGAP26,NFASC,AJAP1,VAMP1,PLCB1,HIF3A,TPM2,TMPRSS5,RPRM" Drug 2464_UP Probenecid [57-66-9]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADORA1,MRTFA,BEGAIN,APBB2,SEMA4G,MPDZ,BMP7,CACNA1I,CA12,THSD7A,CAST,HIP1R,CACNA2D2,CHI3L2,SLIT2,ABCG2,CNN3,ABI3BP,CREM,TMCC2,DTNB,EDN3,EDNRB,ERBB4,CDKL3,AGAP2,TMEM8B,GPR22,PTGDR2,KLF12,KCNJ5,KCNN1,MAP4,MEF2C,NAP1L2,FXYD6,NCAM1,NTRK3,OMG,PDE4D,CCSER2,RELN,PTAFR,PTPRN2,RGS3,MAP6D1,ASIC4,ASAP3,CCDC92,SLC11A1,DOP1A,SOX2,HECW1,LHPP,SYT5,TACR1,IQCE,FAM189A1,TRPC1,SLC13A3,ZNF32,KCNAB1" Drug 5433_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "PLA2G6,C1QTNF1,AMPH,APOC1,RGS20,ASPH,PTCH2,CADM3,CACNA1D,CACNG1,ADGRG1,CHI3L2,CHRNB2,CLCN4,SULT4A1,SLC4A7,GREB1,SPOCK3,DTNA,SIDT2,AASS,AGAP2,KHDRBS3,FYB1,ADAM28,GLS,PRUNE2,MAP4,MSR1,MYO7A,CNOT4,GRAMD1C,ELOVL2,PTPRB,RAB3A,RAD52,FRMPD1,SLC1A7,SLC2A5,FAM214B,SLCO1A2,CDK5RAP2,LIMCH1,PDZRN3,ZCCHC24,ZHX3,IZUMO4,SPTAN1,ATP10B,ZC4H2,ZEB1,SZT2,PSD3,CRTC1,PCDHA5,ZKSCAN5,UBE3A,WIPF1,ZIC3,SLC30A3,NT5M,SLC17A7" Drug 4615_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "RALGAPA1,AK2,ADGRF5,ASCL1,ZSCAN18,BRINP2,ALDH7A1,RUNX1T1,SLC16A4,CDH8,CHGA,CHN2,TAOK2,CLTB,VAX2,PCYT1B,ENTPD4,VCAN,PDE4DIP,CNIH3,ABCC9,PLXNC1,CALCRL,EFS,ZNF549,EZH1,FLT1,DKK3,GALC,ATP8A2,GNAL,PRUNE2,GPR22,SPACA9,GRIK5,HLF,ICA1,LAMA2,NF1,P2RY1,PCSK5,STRN3,SPATA6,MASP1,SNRK,ZMAT4,RGS12,KCTD17,TMEM206,TRAPPC13,NLGN1,ANKRD6,BEX1,ARHGAP26,DDN,PHLDB1,KIAA1107,KLHL4,PCDHGB6,SPX,VGF,KCNK12" Drug 6401_DN F0447-0125; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "TTYH1,ADCY6,AMT,SEMA7A,PKP4,PRX,ATP6V0A1,PROM1,CACNG1,NGB,USP2,RAB26,ABI3BP,TCEAL2,NRG2,CSF1,SDC3,CTNND2,MYEF2,DSCAM,ABCC9,EDNRA,SEMA3D,LPAR6,ETV1,FGFR1,FLT1,CGREF1,FYB1,DENND2A,CSDC2,RUNDC3A,RAB30,GPM6A,GRIK5,GRM1,HAS2,HSD17B1,HTR2A,VWA5A,MATN3,AFDN,MMP16,MN1,CD200,NPR2,PROX1,RGS7,TCP11L1,ASAP3,SLC15A2,SCN3B,SOX10,SP4,NFASC,PHLDB1,CRTC1,TK2,TNS1,ZMYND8,VGF,ZFP37" Drug 3320_UP Nitrofural [59-87-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ABHD6,ADRA1D,BIN1,CDC42BPA,APBA2,APC,APLP1,ATM,BAIAP3,CRLF1,ZFYVE9,STOML1,SULT4A1,ABI3BP,CSF1R,ARHGEF10,CNTNAP2,CTIF,MFAP3L,NTM,LRRC17,FGFR3,FHL1,FLNC,POLL,GNG4,GRM1,GRM7,GRM8,IRAK3,KCNJ5,KCNMA1,AFDN,ADAM22,MYT1,P2RY1,PURG,LRP12,POU3F2,MAPK8,SAMD9,PLPPR1,RAD52,C1orf54,ASIC4,ASAP3,NLGN1,SLC1A7,SLC11A1,CLSTN2,INKA2,PCDHGA10,SYNE1,OBSL1,DAAM2,TRIO,VIPR2,WIPF1,SPHK2,NT5M,TIGD6,JPH3" Drug 6815_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "SYN3,ADORA3,AP2A2,C1QTNF1,MRTFA,BEGAIN,BIN1,ADGRB3,CACNA1I,INA,ARHGAP33,CLGN,NECTIN3,CSF1R,RIMS3,SPOCK2,RABGAP1L,DTNA,EDNRA,EFNB3,MBNL2,C3orf18,VPS13B,ERCC2,FGFR3,AFF2,SORBS1,FAM49B,TPK1,GNG3,GPD2,HNMT,IL6R,ITGAM,KPNA5,MIA2,CD200,ADAM22,MX1,ZNF862,NDP,NDUFA5,NPTX1,CDK14,LRP12,PACSIN1,PRKCB,PLEKHB2,RAD52,ASAP3,PPP4R3A,FAM214B,EFHD1,LIMCH1,ZCCHC24,AJAP1,PLCB1,AGTPBP1,DMXL2,TNS1,OSBP2,NT5M" Drug 3978_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "NME5,MRTFA,DNAH17,MARK4,ASPH,BRINP2,SCAPER,MTMR3,CFAP410,RUNX1T1,CBFA2T2,TAOK2,NMT2,CLTB,CSF1R,GREB1,CYBB,DAPK1,RUSC2,EDNRA,EFNB3,ELAVL2,FGFR1,FGFR3,AFF2,FAM49B,RND1,ADAMTS13,ATXN2L,KCNJ5,KCNMA1,KCNN1,KIF5A,VWA5A,ADAM22,MSR1,MX1,NF1,SLC11A2,PPP2R2B,CEP41,MAPK7,PTPRD,FBXW7,SEMA6D,BCAN,RPH3A,SLC2A5,ZCCHC24,SP4,PEG10,ARHGAP26,ATP10B,PHLDB1,ARC,SYN2,CRTC1,SLC35G2,VIPR2,SPHK2,EMSY,NUP214" Drug 6309_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ARID1A,PDE8B,KIF1A,SCAPER,SCARB1,CDH10,NRXN3,QKI,CNTFR,CRMP1,ARMCX2,DNAJC6,KIAA0753,DMPK,ATN1,EDIL3,EFNA3,TENM1,COQ7,ETV1,RRAGB,ZNF589,PRELID3A,HBS1L,ZMYND11,GPR17,SPACA9,GRIK5,GRIN1,GRM1,HSF2,KHK,KIFC3,MDFI,NF1,CNOT4,NOVA2,OPRL1,PIK3CD,PLCD1,SAMD9,PTCH1,PTPRB,PTPRH,RAB3A,RAB3IL1,RAD52,RALGDS,ENOX1,SUGCT,CCDC88A,KDM4B,DDN,INKA2,PHLDB1,ARHGEF9,KIAA1107,ARHGEF12,CRTC1,PIK3R5,NDRG4,NT5M" Drug 6364_DN CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "TKTL1,ARID1A,ADRA1D,APBB2,CDC14B,CDK13,ASPH,B3GALT2,CADM3,ADGRB2,MYRF,CFAP410,SCARB1,COL9A1,NRG2,CDON,ATN1,HEYL,MBNL2,SORBS3,TNK2,ELAVL4,VPS13B,EXTL1,F5,DLC1,HPCAL4,GAB1,TMEM8B,SIGLEC8,CPLX2,SRCAP,GPM6B,ADAMTS13,GRM8,HLF,KCNA2,KCNN1,MAPT,MMP16,MOBP,NNAT,NOVA2,NTRK2,PROX1,PTHLH,PTPRN,ZMAT4,RGS10,SCN2B,SH3BP2,FRMPD1,SLC1A7,DOK5,EMC1,ARHGAP26,ACSBG1,PLCB1,DOCK9,TRIO,NT5M,STMN4" Drug 7319_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "KCNAB2,APC,SEMA4G,MARK4,ALDH4A1,CADM3,SYNJ2,MYRF,CACNA1A,CACNA2D2,AKAP7,AKAP6,IFFO1,CTNND2,HDAC9,ATN1,DENND4A,EFS,FOXG1,PDLIM5,GAB1,DISC1,RUNDC3A,GLS,ELOVL5,SCIN,DIPK1A,VWA5A,MEIS1,MMP16,NCAM1,NF1,PDE4D,MINDY2,MAPK7,CNNM2,TMEM231,RGS4,RGS10,TTLL7,NEK11,ZNF821,AMBRA1,PEX26,PPP4R3A,SLC6A8,SLC9A5,SLC14A1,TSNAXIP1,IZUMO4,MAPK8IP3,JMJD6,EXOC7,THRA,TIAM1,TK2,TPM2,OSBP2,VIPR2,WIPF1,SPHK2,EMSY" Drug 3544_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADORA2A,KIAA1324,SPARCL1,AMT,APBA2,CDK13,CACNA1D,RUNX1T1,CBFA2T2,LHX2,HOMER3,FAM149A,WHRN,DYNC1I1,CDON,DTNB,EFNA3,EFNB3,PLXNC1,ELAVL3,C3orf18,ERBB4,KIAA1109,FGF1,BAIAP2,AFF2,ZNF44,GAD2,SRCAP,ADAM28,LYVE1,RND1,LPAR4,GRM1,GRM3,AP4S1,KLF12,KCNMA1,PACRG,ADAM22,NEUROD1,NNAT,PAX6,NLE1,PPARA,SAMD9,ENOX1,RGS12,RASA3,RPH3A,COA1,ZNF415,RBM26,CLSTN2,ARC,WSCD1,TNS1,CHST5,AMACR,TRO,UBE3A,KCNAB1" Drug 7494_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.61E-08 1.77E-03 1.92E-06 2.18E-05 62 199 "ADRB2,PLA2G6,APAF1,APC,BRINP2,ALDH4A1,STX16,KYAT1,CHRNA4,HOMER3,NRG2,CSF1,VCAN,KIAA0513,RIMS3,BRINP1,RUSC2,RCAN1,DTNA,CELSR3,EGFR,MBNL2,TENM1,ING4,RGS17,HSD17B14,LRRC23,ANKMY1,ACSL4,FGFR1,ANKFY1,PDLIM5,GPM6B,ICA1,KCND3,KCNN1,KIF5C,MIA2,MX1,NEK1,PFKFB2,MAPK7,PTN,ZSCAN2,PID1,SH3TC2,RGS4,SH3BP2,BTBD7,ZNF667,KDM4C,SEMA4A,SMG6,TCF4,TRIM2,TNS2,SLC35G2,BEX4,FAM155A,PRDM2,EPM2A,PHTF2" Drug 2160_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "MTUS1,AMPH,APAF1,APOC1,APP,CDC14B,SEMA4G,MYOM1,CACNA1I,NEURL1,CLCN4,AKAP7,SEC14L5,RUSC2,DLG3,DSCAM,EGFR,SORBS3,OLIG2,LRRC17,F5,FOXG1,GALC,ERAP1,ALDH1L1,SRCAP,RND1,ATF7,LILRA2,SLC2A6,DHX35,ICA1,IL6ST,KCNB1,MAP4,SCAMP5,NCAM1,SLCO1C1,ODF2,ST8SIA5,PLCD1,PTPA,BCAS3,PTPN13,RIPOR1,NEK11,MAP6D1,GALNT10,SLC1A7,EPN2,KBTBD4,KIF13A,RBM34,ATP10B,MAPK8IP3,TBL1X,KCTD2,RUNDC3B,MKRN3,LAMP5,SLC17A7" Drug 5113_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "MRTFA,TRMT9B,PPFIA4,DDO,ADGRB1,NRP2,CACNG1,BRSK2,RUNX1T1,CSF1R,PLCH2,SPOCK2,MFAP3L,EXOG,DTNA,TOM1,ST8SIA3,HIPK3,COQ7,NRN1,FGF1,SEMA6C,GABRA2,ZNF44,GATM,POLL,LPAR4,SPACA9,HLF,ICA1,TJAP1,ITGA7,ITIH2,KCNJ3,KCNJ4,MAPT,MOBP,MPP2,PDE4B,SNRK,ELOVL2,PTPRN2,ZSCAN2,TMEM231,KHDRBS2,GAL3ST4,RGS12,TCP11L1,RPS6KA2,IL17RB,ZNF821,SLC1A2,SLC4A3,SLC1A7,MAPK8IP3,PCDHGA10,TK2,CDK20,TRH,LAT2,PRDM2" Drug 6696_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ACTN2,LTBP4,ALK,APAF1,APBB1,APC,ADGRB2,BMP7,SYNJ2,SCAPER,ENTPD2,ADGRG1,TAOK2,CLCN4,ARMC8,HAPLN1,CSF1R,VCAN,CTNND2,RIPOR2,JAKMIP2,MFAP3L,DTNA,EDIL3,EDN3,HIPK3,EFNA3,MBNL2,PLXNC1,ING4,EPHA5,ZNF589,FGFR1,FOXG1,GLYR1,GPER1,GRM8,KLF12,IL6R,MDM4,KITLG,NF1,NLE1,ELOVL2,ZSCAN32,RAB3IL1,RAD52,SFPQ,SLC20A2,CXXC4,ZSWIM8,HECW1,TROVE2,COBL,ATP11A,CRB1,UBTF,NSD2,ZNF24,WNK1,GAN" Drug 3901_UP U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ASIC1,NLGN4X,ALK,AMPD3,DDX3Y,CACNA1I,CACNA2D1,CLCN4,NMT2,WHRN,SEC14L5,HEPH,CNIH3,SHANK1,ST8SIA3,SRPK3,ELN,VPS13B,CEND1,DLC1,FGFR1,CAMKK2,GFER,GNAO1,GRIK5,GRM1,SOX21,ITPKA,KCNJ5,KCNN1,KCNN2,KIFC3,MARK1,NELL2,NNAT,CNOT4,PIK3R1,LRP12,NECAB2,MINDY2,PTCH1,ELOVL2,ZSCAN32,TRIM68,RGS12,RPS6KA2,CPEB3,SLC2A5,LIMS2,SLC6A9,SLN,SNCA,KDM4B,CLSTN2,PLCB1,ROBO3,HEY2,TNFRSF1B,PRMT8,HIRA,CAMK1G" Drug 6180_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ADD2,ADRA1D,MTUS1,AGT,C1QTNF3,CDC42BPA,ANK2,APAF1,FAM131A,APP,LDLRAD4,CAPN3,HIP1R,CHM,CHRNB2,TAOK2,RAB33A,NMT2,CPS1,CLOCK,VCAN,CTH,CTIF,RUSC2,GSDME,TRAPPC9,RCAN1,SIDT2,OLIG2,CGREF1,FYN,GAB1,GABRA4,USP19,GNG3,GNG4,CACFD1,BTN2A1,ELOVL5,TJAP1,IL6ST,SMAD1,MAP4,OGG1,P2RX7,P2RY1,SERPINE2,RETREG1,SMOX,SLC25A23,MBOAT7,RPS6KA2,FOXRED2,SLC1A3,TSPYL2,DNMBP,TNNT1,CDK20,SMUG1,VIPR2,NT5M" Drug 4593_UP Ethionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ASPHD1,SEMA6A,AMPD3,APC,NRP2,BMPR1B,MTMR3,LDLRAD4,ARHGEF2,DLGAP1,CBARP,RAB28,STOML1,LY86,CABP1,CREM,CSNK1E,PDE4DIP,CNTNAP2,BRINP1,MFAP3L,RABGAP1L,CHRDL1,ATN1,FCF1,ING4,ETV1,VPS26C,FGF1,FGFR1,GAB1,GNG4,GPM6B,GUCY1B1,HLF,VWA5A,MATN3,AFF1,MYO6,NELL2,PDE4D,PPP5C,PRKAR1B,PTHLH,NEK11,SUPT20H,PPP4R3A,PKNOX2,SLC6A9,SNCA,KIF13A,IQSEC2,COLGALT2,SYNE1,CRTC1,TPM1,WIPF1,SPHK2,SEMA3B,PARP11,FAM13C" Drug 2411_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ABAT,AP2A2,MTUS1,TRMT9B,PKP4,APC,CDK5R1,C5,CLCN3,SLC4A7,VCAN,PPP6R2,ZNF337,TM9SF4,MAGI2,DSCAM,CNNM1,EIF1,CDHR1,DLC1,KIAA1109,FOXG1,AGAP2,PDLIM5,GPR153,GAB1,ERAP1,GATM,RUNDC3A,GLS,GPM6B,ICA1,KCND3,KLC1,MEF2C,SCAMP5,NUMA1,OMG,OPCML,P2RY1,PLCD1,PPARA,RIPOR1,RGS4,RGS12,SYNDIG1,CLIP1,GALNT10,FERMT1,SLC20A2,ZCCHC24,EMC1,SS18,TACR1,PDLIM2,ARHGEF12,AP4E1,R3HDM1,TNS1,MAP3K12,EMSY" Drug 2382_UP Bufexamac [2438-72-4]; Up 200; 18uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "MTUS1,SPARCL1,AMPH,APP,LGR5,PRX,ASPH,CHRD,ALDH4A1,CACNA1G,CALB1,CHRNB2,HOMER3,NRG2,CSF1R,KIAA0753,DSCAM,EIF4G2,ING4,LRRC23,CDKL3,KIAA1109,SCARA3,PDLIM5,KHDRBS3,GPR153,PCDH17,PTGDR2,ATXN2L,ACOT7,ICA1,IL12A,KCNN1,KHK,MDFI,MPP2,OPRL1,CDK14,KCTD15,PMP22,RELN,CNTLN,PTAFR,RGS3,GALNT10,FERMT1,DOCK10,FBXO11,SLC8A1,SLC20A2,SOX10,KDM4C,NPAS3,SS18,STX1A,PDLIM2,TBCEL,FLRT2,MAP3K12,GDPD5,GAN" Drug 5474_UP Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "RALGAPA1,ADD2,ADORA1,ALK,PDE8B,MARK4,CFLAR,LDLRAD4,USP2,HOMER3,RCHY1,CSF1,RABGAP1L,SLC12A6,SGK2,MBNL2,EGR3,TNK2,DMTN,STX2,EZH1,F5,CORO2B,DCTN2,ZNF44,SRCAP,GPM6A,GUCY1B1,C2orf72,LIG4,MAN2A2,NFYA,CDK14,LRP12,RAB3A,RAD52,GAL3ST4,MRAS,ASAP3,SLC1A7,SMTN,RIMS1,PEG10,CLASP2,CLSTN2,RGL1,JMJD6,SEMA4A,ROBO3,EXOC7,KIAA0930,RPGRIP1L,PCDHGA10,TEX15,TK2,ZMYND8,KCNK12,NT5M,DNALI1,KCNAB1,SSPN" Drug 6699_DN Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "RALGAPA1,APBB2,APC,APP,PDE8B,KIF1A,NRP2,ST3GAL5,MYRF,ARHGEF1,NRXN3,IQCK,TCEAL2,BAG4,NCOR2,RUSC2,SPOCK3,RABGAP1L,CNNM1,EGFR,EML1,COQ7,DMTN,MTSS1L,ZNF589,KIAA1109,SORBS1,B4GALNT1,SYT17,GBX2,GFER,GPM6B,TDRKH,LPAR4,GRM1,SCIN,IL6ST,DIPK1A,SCAMP5,NUMA1,GRAMD1C,PTN,TMEM231,FAT4,RGS3,ASAP3,SLC4A3,IQSEC2,DDN,MCF2L,KIAA1107,TCF4,DNAH7,THRA,TK2,TPM2,CADM1,XRCC4,KCNAB1,TIGD6,DPF3" Drug 6834_UP Pindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.93E-08 1.93E-03 2.07E-06 2.35E-05 61 195 "ADORA1,NME5,MRTFA,BEGAIN,KCNAB2,SEMA4G,PPP4R4,CFLAR,FUBP1,BAIAP3,CACNG1,CALB2,HIP1R,USP2,ARHGEF1,CLGN,ADGRG1,DNAJB5,AKAP6,IFFO1,RIMS3,DBN1,DTNA,FAM13A,PLEKHO1,FGFR3,GABRA2,HBS1L,SPACA9,GRM7,CELF3,HNMT,AFDN,MPP2,ADAM22,NF1,PDE1C,PGAM2,EPN1,PLP1,MAPK8,ZSCAN2,MYH14,SLC1A7,SLC11A1,ZCCHC24,ZHX3,THSD1,INKA2,KAZN,HEY2,R3HDM1,CABIN1,TRPM2,FLRT2,VLDLR,SLC13A3,PRDM10,SLC17A7,KCNAB1,ITM2C" Drug CID000196705 alpha-CaM Stitch 4.00E-08 1.96E-03 2.10E-06 2.39E-05 28 62 "LRRC7,ALCAM,MYH7B,CALM1,CAMK2B,CAMK2D,KRIT1,CDH2,CTNND2,DLG4,STX2,CAMKK2,B3GAT1,GAP43,GJB1,MAP2,MAPT,CTNNA3,NRGN,PRKCG,RELN,RDX,SHANK2,DDN,STX1A,SYN2,ZIC1,ZIC2" Drug 7043_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.05E-08 1.99E-03 2.12E-06 2.42E-05 58 182 "ADD3,NME5,APLP1,ARNTL,BMP7,ST3GAL5,BAIAP3,SPAG9,CDH18,CLGN,PDE4DIP,DOCK4,DNAJC6,TMCC2,OPTN,EFNA3,ACSL4,TUBB4A,FHL1,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,RAB40B,TDRKH,STON1,SLC2A6,KIF5C,VWA5A,MITF,PCDH9,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,RPS6KA2,SH3GL3,WDR47,PKNOX2,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,KIAA0930,RPGRIP1L,HEY1,BEX4,NPL,RUNDC3B,DNAJC12,SLC30A3,SLC17A7" Drug 3058_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.28E-08 2.10E-03 2.23E-06 2.54E-05 60 191 "ACTN2,NDRG2,SEMA6A,BIN1,EPB41L5,ASCL1,KALRN,REPS2,CDO1,CLGN,CHN2,LHX2,DNAJB5,RAB26,DZIP3,DOCK4,KIAA0513,RIMS3,DNAJC6,AASS,EPB41,EPHB1,APC2,ETV1,TLR7,TBC1D16,NBEA,SIGLEC8,GATM,ADAM28,GLI2,STON1,RAPGEF4,HNMT,KIF5C,MAPT,NF1,PCDH9,PCSK5,SERPINI1,PLCL1,PMP22,SIDT1,PTHLH,MARCH1,TMEM255A,RASGRF1,WLS,SMARCD3,TNIK,PEG10,ELOVL4,RGL1,CAMSAP2,ATP13A2,KLC2,KCNK12,MAP3K12,SLC17A7,FZD3" Drug 5957_DN valinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.28E-08 2.10E-03 2.23E-06 2.54E-05 60 191 "ALK,AMPD3,APBB2,PDXK,DNAH17,BRINP2,CACNA1I,NEURL1,CDC42,LHX2,TPP1,DNAJB5,WHRN,NCOR2,AATK,CTIF,ZNF804A,TMCC2,SLC12A6,FEM1B,EFNA3,EN2,IGSF6,DLC1,CAMSAP1,FOXG1,IQCG,DPYSL4,KHDRBS3,GART,RND1,TDRKH,GPER1,SPACA9,FICD,KCNJ4,VWA5A,MPP2,MX1,PPP5C,PEX5,RET,RGS12,KCTD17,RNASEL,TCP11L1,RPH3A,SNCA,DOP1A,EMC1,SPTB,IQSEC2,PHLDB1,JMJD6,TACC1,TMEM121,TMOD1,ZIC3,EVI5,NUP214" Drug 7417_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.28E-08 2.10E-03 2.23E-06 2.54E-05 60 191 "ADGRF5,APBB2,EPB41L5,ARNTL,ARRB1,MPDZ,CFLAR,ARHGEF7,SCAPER,MTMR3,USP2,MAGI1,FEZ1,CHD5,DCT,FBXL5,DTNA,PHF20L1,EIF4G2,COQ7,MTSS1L,STX2,ANKMY1,TESK2,FOXG1,SYT17,SRCAP,RUNDC3A,ZNF276,SPACA9,RNFT2,HMGCR,INPP5B,MBD1,AFDN,ADAM22,MYO7A,NF1,MBOAT7,PTHLH,RIPOR1,RALGDS,RGS12,KCTD17,SH3GL3,HKDC1,SLC6A9,IQSEC2,KIAA0930,TRIM2,PSD3,PCDHA5,TEX15,RBFOX2,TRH,ZNF189,MAP3K12,HPS4,NUP214,SSPN" Drug 4451_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.28E-08 2.10E-03 2.23E-06 2.54E-05 60 191 "ACTN2,SLC12A5,GRAMD1B,ADRA1D,TRMT9B,ASPH,SLC2A11,BACH1,KSR1,BMP7,TPP1,EDRF1,RABGAP1L,NR1D2,CELSR3,ING4,ETV1,CACNG2,TESK2,EFCAB2,GAB1,RND1,GNG4,FERMT2,GPM6B,STON1,TJAP1,IL6ST,KCNF1,KCNJ4,SMAD1,MMP16,LYRM9,NUMA1,PDE3B,PDE4B,SERPINI1,LRRN3,MAPK8,SNRK,CCDC40,RASGRF1,CCDC102B,TMEM156,ATXN1,ASIC4,SLC11A1,HECW1,ARHGAP26,CDK19,RBM26,CEP68,TCF7L2,SZT2,DOCK9,TEX15,TK2,ZMYND8,ZNF225,SLC17A7" Drug 4444_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.32E-08 2.12E-03 2.25E-06 2.56E-05 54 165 "ABAT,ADRB2,EPB41L5,ARNTL,ST3GAL5,SYNGR3,CHN2,NRXN3,ABCG1,PDE4DIP,CTH,DNAJC6,JAKMIP2,C2CD2L,PLPPR4,EFNA3,RGS17,F3,TAOK3,BAIAP2,SORBS1,FYN,CYP46A1,RND1,GLS,GUCY1B1,DIPK1A,ITGA7,KCNH2,KIF5C,LIFR,VWA5A,MAP2,MMP16,PCDH9,PDGFRA,SERPINI1,PRPH,SYTL2,ACSS3,ENOX1,RGS4,SH3GL3,KDM4B,DOP1A,THSD1,ELOVL4,CEP68,RGL1,SYT1,SSBP2,CADM1,DNAJC12,SLC30A3" Drug CID000003140 D-N-Q Stitch 4.32E-08 2.12E-03 2.25E-06 2.56E-05 34 84 "ADORA1,EIF4G2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,GLRB,PCSK1N,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NOS1,NUCB1,PDYN,ENOX1,SLC6A1,SYP,MAP3K12" Drug CID000001232 HA-966 Stitch 4.36E-08 2.14E-03 2.27E-06 2.58E-05 21 39 "GPHN,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,JMJD6,MLST8,TPM3,TRH" Drug 873_UP trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.37E-08 2.14E-03 2.27E-06 2.58E-05 57 178 "ABHD6,ADD3,FZD9,ST3GAL5,SCAPER,BAIAP3,CLGN,AKAP12,PDE4DIP,KIAA0513,ARMCX2,DNAJC6,OPTN,EFNA3,RASGRP2,TUBB4A,TAOK3,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,STON1,RNFT2,KIF5C,MITF,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,RAB3A,RPS6KA2,SH3GL3,SYBU,ZNF365,WDR47,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,HEY1,RUNDC3B,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug ctd:D004237 Diuron CTD 4.41E-08 2.16E-03 2.29E-06 2.60E-05 355 1742 "SERPINA3,ACHE,SYS1,ACTN1,TMEM132B,GALNT16,ADCY6,TMCC3,ADD3,AP2A2,AP1B1,KLHL13,AGT,SPARCL1,ALCAM,SRPX,CEP126,ARHGAP20,LTBP4,GPRASP2,AMT,ANK2,PI16,PKP4,ANXA7,APBB2,APP,MARCH3,NCOA1,DYNLL1,ATP1A2,ATP1B3,ATP2A2,ATP2B1,CADM3,DOCK11,SEC11C,CFLAR,PROM1,SCAPER,MTMR2,C1QC,IL33,CA8,CA12,CALM1,HAP1,NGB,CAMK2D,CANX,CAST,SPAG9,ARHGEF25,CBR1,CD86,SCARB1,ENTPD2,DCLK1,LRRFIP1,CDO1,CCPG1,CLGN,CFL2,FOXN3,PLEKHB1,MS4A7,B4GALT6,JAM2,MYL6B,FAM189A2,FADS2,QKI,CNN3,ARHGEF6,COL11A2,ABI3BP,ZNF521,CP,NECTIN3,FAM171B,C2CD2,RBM39,AKAP12,GDA,FEZ2,MICAL2,VCAN,CST3,DZIP3,RIPOR2,ARHGAP24,TOX,SCRN1,SPOCK2,BRINP1,DBN1,YTHDC1,DCT,C2CD2L,ZC3H11A,RABGAP1L,DLG3,DMPK,OLIG1,CPEB2,DPYSL2,DTNB,ECM2,ABCC5,FIS1,EBF1,FEM1B,EEF1D,FRY,LPAR6,EIF4G1,CERCAM,PCOLCE2,EML1,EIF1,ENO2,EPB41L2,LRRC17,RASGRP2,SRRM1,NCALD,MRVI1,EZH1,F3,FAM198B,ACSL4,TAOK3,EFEMP1,STRADA,FGF1,FGFR1,AMOTL2,FHL1,MEX3B,FLT1,FOLR2,TACC2,PDLIM5,RASL10A,ERGIC3,ST6GALNAC3,SARAF,TPPP3,MPP6,FYB1,FYN,ILDR2,RAPGEF6,NCKAP1,GAP43,ACSS1,STARD10,DNER,GCNT2,SESN1,GHR,LYVE1,DHRS4,TCERG1,GLS,TOX3,GLUL,HTATSF1,KCNMB4,LOXL3,FERMT2,CNDP1,GPD1,GPM6A,EML4,GRB10,PLCD4,GSN,GSTM5,GUCY1A1,IRAK3,HAS2,HRH3,CPT1C,HSP90AA1,MSL1,SOWAHA,IGF1,PLD5,IL6ST,IL11RA,ITGA7,KLHL23,KIFC3,KLRC3,KTN1,LAMA2,PIK3AP1,MAOB,MAP2,MATN2,MATN3,KITLG,MITF,AFDN,MMP16,DBNL,COMMD5,CCDC80,NAP1L1,NAP1L2,NBL1,NFE2L2,NFIX,NNAT,NPR2,PCBP3,NTRK2,DDR2,OGDH,CLDN11,PC,PCSK5,PDE2A,PDGFRA,ENPP2,TMOD2,CYTL1,SERPINE2,SERPINI1,ANLN,PIK3R1,RETREG1,PKM,GPSM2,FXYD1,PLTP,PLXNB1,PMP22,PRRX1,MED1,MINDY2,PPP1R1A,PPP2R2B,NKAIN4,PRKACB,PRKCB,GRAMD1C,VPS13C,DEF8,GDPD2,PXK,PTPRO,PTPRZ1,RAB5B,ROGDI,RBBP6,RDX,RGS10,PBRM1,SETD5,RPL38,PRR5L,EMID1,LGR4,RPS20,PAQR6,HUNK,CLIP1,RTN1,S100B,SCP2,SMPD3,SEC14L1,SFPQ,SGK1,SCG5,SH3BGR,SHMT2,ST6GAL1,ANKRD6,SLC1A6,SMTN,LIMS2,SLC6A9,ARHGEF40,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SCMH1,EFHD1,CPEB4,SMARCE1,KIF13A,LMBRD1,ZCCHC24,KDM4C,ZC3H13,KIF1B,SMOC1,KANK1,PRRC2C,COBL,TACC1,SEMA4A,WWC1,TBL1X,DMXL2,ZEB1,TRIM2,SLC35G2,PCDHA1,TEK,TF,ITGB3BP,ZNF106,CDH22,SLC44A1,ZFP91,TMPO,PRRT1,TNS1,TPD52,TPM1,TPM2,TPM4,SYNPO2,TTC3,TUBB2A,CADM1,RPRM,UCHL1,GORASP1,VLDLR,RBFOX3,P2RY12,PORCN,PCDH20,AGMO,WNK1,TUBA1A,ADAMTS9,NAV2,PDSS2,HRASLS,MARCH8,KAT6A,HNRNPA3,PHTF2,ACTR3B,JMJD1C,VANGL2,MSRB3,SSPN" Drug 7367_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "APBB2,SHROOM2,ARHGDIG,SLC4A4,RUNX1T1,CACNA2D2,ADGRG1,CHRNB2,DNAJB5,CNTN1,AKAP6,WHRN,AKAP5,TENM4,EDRF1,SEC14L5,CNNM1,OPTN,ZNF391,ETV1,FGF1,CAMSAP1,SRCAP,ZNF276,GLI2,GLYR1,GRIK5,GRM1,IL12A,MGAT3,ZNF862,NF1,NOVA1,NPR2,OPCML,CLDN11,FAM120C,RAB3A,ZCWPW1,CSRNP3,SCNN1D,SH3BP2,ASAP3,NLGN1,ANKRD6,SLC1A7,SNCA,SOX15,UNC5B,SPTAN1,TROVE2,THSD1,VAMP1,CABIN1,CHST5,TRIO,RUNDC3B,TRPC3,ZMYND8,PRDM2,SCG2,UBE3B" Drug 5497_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "NDRG2,FZD9,BIN1,FAM131A,ARHGDIG,ARSE,CFLAR,GYG2,CACNA1G,CACNG1,ARHGEF1,CDC42,CDH18,RCBTB2,SLC24A2,AKAP6,CPS1,MICAL2,RIMS2,EDRF1,TBC1D5,MAML1,DBN1,LYPD1,GSDME,DMTN,BAIAP2,FHL1,PDLIM5,CNTRL,GRIN1,JAK2,KCNJ3,LIG4,MAN2A2,MSR1,PDE2A,LRP12,PRKCB,SNRK,PTPRO,FAM120C,ATG16L1,CRTAC1,SYNDIG1,SELL,ZNF821,SCG5,SLC2A5,SLN,COA1,DOK5,LMO3,TAC3,SEMA4A,TEX15,TPM2,RUNDC3B,TRPC1,VAV2,ZIC3,PHTF2" Drug 6687_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "ALK,MRTFA,ATP1A3,NRP2,BTRC,CALB2,SCARB1,CHI3L2,TAOK2,RAB28,CLCN4,IFFO1,HAPLN1,MICAL2,TOX,RIMS3,MFAP3L,AK5,ABCC9,TNK2,FAM198B,ATP8A1,ZNF589,FGFR1,ZNF44,GLI2,RAPGEF4,STMN2,GRM8,IL6R,IL6ST,KCNC1,KCND3,KCNJ3,LSS,MDM4,MN1,MOBP,ADAM22,MT1M,NF1,NPTX1,OMG,CAMKV,PPP1R1A,MAPK8,ZSCAN32,PTPRN2,RGS12,KCTD17,KLHDC8A,FRMPD1,DZIP1,SLC11A1,SNAP25,INKA2,TACR1,HIF3A,ZNF225,PRDM2,EVI5,SCG2" Drug 6970_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "SLC12A5,ADRA1D,FAM131A,APOC1,BCAS1,GYG2,CBARP,SOCS6,B4GALT6,CHRNB2,CLU,ENTPD4,FAM169A,DBN1,DCT,MED12,CDON,DRD1,SIDT2,RBM12,PHF20L1,EGR3,EIF4G2,RRAGB,FER,ANKFY1,DPYSL4,GPR153,GABRA2,DISC1,GLS,SPACA9,INPP5B,ITPKB,KPNA5,MAPT,PPARA,MAPK7,WDR25,ZSCAN32,RAD52,GTDC1,GSTCD,RYR1,SBF1,ASAP3,DZIP1,EPN2,SPTAN1,SPART,ROBO3,RPGRIP1L,TK2,TPM1,PLPPR2,VIPR2,ZNF711,REEP1,MAP3K12,EMSY,ITM2C,ST7" Drug 3167_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "DPF1,APLP1,APP,LGR5,PPP4R4,ARHGDIG,ALDH7A1,N4BP2L1,ADGRB1,CFLAR,NEURL1,CDH2,ARHGAP33,ADGRG1,EPS15L1,FAM149A,NCOR2,VCAN,DTNA,DTNB,MBNL2,TENM1,ELN,C3orf18,CORO2B,AGAP2,FLNC,SEPT9,GPM6B,GRIK1,GRM1,GSN,IRAK3,GPR45,VSIG4,IGF1,IL6R,KCNC1,KCNJ5,KPNA5,MSR1,TAGLN3,OPRL1,PCSK5,GPR85,SAMD9,PTPRD,FAM120C,RPH3A,LIMCH1,HECW1,NFASC,ARC,SYN2,PCDHA2,SEZ6L,PRMT8,BEST1,ADAMTS9,SCG2,FAM13C,SSPN" Drug 3779_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "SYN3,ADCY2,APBB2,APC,ATP2B2,CADM3,KIF1A,RGS9,GYG2,CFAP410,CALB2,CH25H,SLC24A2,SULT4A1,AKAP6,NCOR2,ABCG1,RGS6,LRIG1,RIMS2,CX3CR1,INTS1,SPOCK3,EBI3,MRNIP,B3GAT1,GABRB3,GNAL,GNAO1,GRM3,SOX21,IRF8,KCNN1,KCNQ3,VWA5A,CNOT4,NPY,NTRK2,NTRK3,PCDHGC3,PDE4A,GPR85,PLXNB1,MASP1,PTPRH,PTPRO,RAD52,RET,ASAP3,SLA,KANSL3,UNC5B,SPTB,TACR1,DOCK9,OBSL1,TEK,ICAM5,PDIA2,PRDM2,MVB12B,NLRP3" Drug 6032_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "KDM5D,SEMA6A,BIN1,AMT,ANK1,SLC4A4,CADM3,BSN,CALB1,TAOK2,CLCN4,SNCAIP,CHD5,SPOCK2,ATN1,EBI3,HSD17B14,EFS,FGFR1,FGR,AGAP2,AFF2,FYB1,CPLX2,GFER,GNAS,GNG3,GPR37,GRIA4,CACFD1,GRM7,GUCY1A2,HLF,C2orf72,KCNJ5,KCNJ9,CD200,ADAM22,TAGLN3,NCAM1,NOS1,PDE2A,MASP1,RFX2,KCNIP2,ZNF821,ST6GAL1,OGDHL,MYH15,SNCA,CAND2,UNC5B,ARHGAP26,ATP10B,INKA2,RGL1,PCDHGA10,TTPA,PDIA2,CA10,HRASLS,JPH3" Drug 6688_DN Debrisoquin sulfate [581-88-4]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-08 2.18E-03 2.29E-06 2.60E-05 62 200 "CDC42BPA,APP,DNAH17,MARK4,KIF1A,ST3GAL5,STOML1,ABCG2,DNAJB5,TCEAL2,CSF1R,CSNK1E,BRINP1,CHRDL1,SGK2,LRRC23,MTSS1L,AFF2,TRMO,OGA,FYB1,GAD1,GFER,GNG4,GPM6B,TDRKH,GRK4,GRM1,SHISAL1,SCIN,MGAT3,AFF1,MMP16,NUMA1,OPCML,CLDN11,PDE4A,PIK3R1,PPARA,GRAMD1C,PTN,C1orf54,KIRREL1,ROM1,ASAP3,PEX26,RBM34,UNC5B,BEX1,DDN,ATP10B,TROVE2,PLCB1,MCF2L,ADGRL3,TK2,TNS1,TPM2,WIPF1,KLC2,KCNAB1,EPM2A" Drug CID000176265 gacyclidine Stitch 4.54E-08 2.22E-03 2.33E-06 2.65E-05 20 36 "ACHE,BCHE,ENO2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,LAMP2,TRH,RTN4" Drug CID000104962 C6H12NO5P Stitch 4.54E-08 2.22E-03 2.33E-06 2.65E-05 20 36 "ADORA2A,CA4,DRD1,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,APTX" Drug 5669_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "SYN3,PLA2G6,AMPH,APBA2,ADGRB1,CDK5R2,CFAP410,CACNG1,CALB2,CAMK2A,NRXN3,STOML1,DNAJB5,NCOR2,CSF1,VCAN,PDE4DIP,SPOCK3,DMD,DSCAM,EFNB3,TENM1,ETV1,ANKMY1,CEND1,ZNF589,FYB1,GAD2,NEU3,RND1,GRK4,GRM1,GRM8,PTGDR2,KLF12,ICA1,TJAP1,LAMA2,VWA5A,ADAM11,BCO1,MYH7,NAP1L3,NCF2,NEUROD1,NF1,NUMA1,OMG,PCDHGC3,PMP2,GRAMD1C,PTPRB,PTPRD,CEP97,GAL3ST4,SALL1,ZFP2,EPN2,VAMP1,ATP11A,EPM2A" Drug 4524_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "SYN3,ACHE,ADORA1,C1QTNF3,ANK2,CDK13,ZSCAN18,CCDC181,BTRC,CACNG1,THSD7A,CAMK2B,NEURL1,CNTFR,SUSD5,VCAN,CTNND2,MAGI2,RABGAP1L,EDNRB,SGK2,SRPK3,ZNF391,F5,ABCA8,GABRA2,GCNT2,GNAO1,GNG4,GPM6B,GPR19,KCND3,KCNN1,KIF5C,MAPT,MMP16,NF1,PDE4B,PDE4D,PTAFR,PLPPR1,PTPRH,ZMAT4,RGS7,TCP11L1,RASA3,FNDC3A,SLA,ZNF334,SLN,SP4,DDN,TROVE2,ARC,SYT5,TACR1,AHCYL2,VIPR2,XRCC4,PRDM2,KCNAB1" Drug 5831_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ACTN2,CDC14B,CDK13,ALDH7A1,CFLAR,KSR1,ST3GAL5,SCAPER,CFAP410,CAMK2B,B4GALT6,HOMER3,ARMC8,HAPLN1,VCAN,SEC14L5,GIT2,KIAA0753,SRGAP3,PDLIM5,GNG4,GPR17,GRM8,TJAP1,KCND3,KIFC3,ADAM22,LYRM9,SLC11A2,PALM,SERPINI1,PPARA,MINDY2,LRRN3,MAPK8,PTPRE,FAM120C,RAB3IL1,PID1,RAD52,RGS7,RGS10,SBF1,PREX2,EPN2,FAM214B,ELMO2,SNAP25,TMCC1,HECW1,PHLDB1,VAMP1,IQCE,CRTC1,AHCYL2,UBE2H,TFIP11,EVI5,MPPE1,NUP214,DPF3" Drug 4355_UP Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ADORA3,LTBP4,AMPD3,APC,DDX3Y,CFAP410,RUNX1T1,CCK,CDH8,CNTN1,AKAP6,WHRN,AKAP5,TENM4,SPOCK2,CTIF,EXOG,TRAPPC9,DYRK1A,SEMA3D,EGFR,AASS,CDHR1,KIAA1109,FYB1,SEPT9,GPM6A,GPR22,GRM7,KCNB1,KCNJ5,MMP16,MN1,MOBP,TAGLN3,NPTX2,P2RY1,PIK3CD,MINDY2,CEP41,VPS13C,FAT4,KCTD17,RYR1,SLC1A7,SLC11A1,SHANK2,TNIK,ARHGAP26,CDK19,NPAS3,AJAP1,KIAA1107,HIF3A,HEY1,TNS1,WIPF1,LAT2,STMN4,KCNAB1,MVB12B" Drug 5259_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ASIC2,NDRG2,ADORA1,NME5,AMPD3,CDC42BPA,ATP2A2,AZGP1,CDO1,CHN2,CLCN4,NRXN1,SULT4A1,LY86,CRMP1,SNCAIP,DCAF4,AK5,ATN1,ECM2,DYRK1A,ST8SIA3,SUGP2,F5,CORO2B,FOXG1,C1orf61,AFF2,GABRA5,GAD2,RND1,ADAMTS13,GRIK5,GRM1,PTGDR2,MOBP,PLCL1,EPN1,PRKCB,PTHLH,PTN,PID1,ATG16L1,SEMA6D,ASAP3,FAM214B,IZUMO4,TSPYL2,CLSTN2,STX1A,SYT11,JMJD6,VAMP1,SYN2,SYT5,SLC19A3,PIK3R5,FAM155A,LAT2,EVI5,AP3B2" Drug 4111_UP Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ADORA3,AMPD3,GAS7,ARRB1,ASPH,ATP1A2,RCBTB2,SULT4A1,WHRN,TCEAL2,CRY2,AATK,ARMCX2,ATN1,SNX29,EFNA3,EPHB1,CEND1,SCML2,SORBS1,KHDRBS3,SRCAP,CSDC2,C1QL1,GLS,ATF7,ICA1,MSI1,ADAM22,OPCML,PDE3B,PLCD1,C19orf57,CEP41,PRKCB,MAPK7,ZSCAN2,TRIM68,RGS10,PNMA8A,EMID1,STUM,SH3BP2,PPP1R9A,DOCK10,SLC1A3,PKNOX2,LIMCH1,DOP1A,HECW1,CDK19,KIAA1107,PCDHGA10,CDK20,UBE2H,UGT8,ZIC3,SLC17A7,KCNAB1,PARP11,SSPN" Drug 6880_UP BAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ASPHD1,AP2A2,ALCAM,BIN1,ANK3,FAM131A,APP,BAIAP3,CFAP410,FOXN3,CHRNB2,NMT2,QKI,CSNK1E,DZIP3,HS3ST2,DTNA,TOM1,EGFR,PLEKHO1,F3,FGF1,CGREF1,GLYR1,MSL3,POLL,GNG3,MUM1,HNMT,KIF5C,MYO9A,ZNF862,NOS1,TREM2,PIK3R1,PRKACB,ATG16L1,RGS10,MYH14,GSTCD,TCP11L1,PAQR6,SBF1,FBXO11,MAPKBP1,TMCC1,ZCCHC24,ZHX3,SS18,MAPK8IP3,ELOVL4,ARHGEF9,VPS13A,RPGRIP1L,PSD3,ICAM5,TSN,KLC2,SLC30A3,SEMA3B,MPPE1" Drug 3783_DN Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ALK,CDC42BPA,PPP4R4,ADGRB2,BAIAP3,CACNG1,HAP1,NEURL1,CDH10,ABCG2,DNAJB5,RAB26,CPS1,DCAF4,RIMS3,DMPK,HIPK3,CELSR3,SORBS3,TNK2,PLEKHO1,ETV1,F5,HPCAL4,CGREF1,GAD2,SIGLEC8,SRCAP,GSTM5,PTGDR2,ICA1,TJAP1,INPP5B,KCNJ5,LSS,TAGLN3,NELL2,NF1,NPR2,NTRK2,NLE1,PPARA,PRPH,GON4L,SNRK,RIPOR1,ACSS3,RAD52,SUSD4,RFX2,RGS4,NEK11,FAM214B,SLC6A9,ZNF334,OGDHL,DDN,TBCEL,TNS1,VGF,LAT2" Drug 5800_UP Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "NME5,ANK1,ATP1A3,ATP6V0A1,BMP7,SCAPER,MTMR3,BTRC,HAP1,INA,SCARB1,LARGE1,CRLF1,STOML1,HOMER3,AKAP5,ENTPD4,GPRASP1,ARMCX2,DRP2,ATN1,MBNL2,PLXNC1,EZH1,FGF1,GABRA2,NEU3,POLL,GSN,ELOVL5,ITGA7,MAPT,SLC11A2,NRCAM,PDE2A,PDE4D,TMOD2,POU3F4,VPS13C,PTN,PTPRB,NKAIN1,ACSS3,FOXRED2,STUM,RASA3,HKDC1,KANSL3,SHANK2,DOK5,HECW1,SPP1,ZBTB43,INKA2,SYP,TEX15,TEK,ZMYND8,FLRT2,KCNAB1,NLRP3" Drug 6171_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ASPHD1,MTUS1,APBB2,CDC14B,CACNA1I,THSD7A,NEURL1,CHN2,LHX2,CREM,CSF1,FEZ1,PDE4DIP,CTNND2,RIMS3,DNAJC6,DLG3,EEF1A2,OPTN,MBNL2,VPS13B,ETV1,TLR7,EYA1,FER,FGFR1,CAP2,GLRB,GPR19,PCLO,HLF,KIF5C,NCAM1,NELL2,NRCAM,NRGN,OPRL1,SERPINE2,SERPINI1,SIDT1,PTPRN2,TMEM231,RAB3IL1,WLS,GALNT10,SH3BGR,PPM1E,CPEB3,PALLD,KDM4B,TACR1,IQCE,TRIM2,PCDHGA1,PSD3,TPM1,AMACR,TRIM9,PRDM10,KCNAB1,NUP214" Drug 4331_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ACTN2,APAF1,PPP4R4,ASPH,CACNA1I,CFAP410,CD38,NEURL1,CDC27,PLAA,SULT4A1,RIMS2,DAPK1,BRINP1,AK5,RABGAP1L,ABCC9,SNX29,EDNRA,PLXNC1,ELN,ETV1,GPR75,GLS,GPM6A,ADAMTS13,ICA1,IL6ST,KCNJ5,KIF5C,MAP4,TM6SF1,MMP16,NOVA2,TREM2,SNTG1,PAK3,PDE2A,PIK3R1,STRN3,PRKAB2,PKN2,MAPK8,PROX1,RAD52,PBRM1,STUM,RBM34,SP4,IZUMO4,SYN2,RALYL,ICAM5,ZMYND8,CA14,FLRT2,SF1,WNK1,NT5M,SLC17A7,KCNAB1" Drug 5878_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "APC,CDC14B,ARNTL,ALDH4A1,ATP2B3,CFAP410,KALRN,MAP7,CBFA2T2,CDC42,SOCS6,ASIC3,TPP1,MFAP3L,TUBD1,LRRC17,ZNF589,IQCG,SEPT9,ATP8A2,GPR75,POLL,GPM6B,TDRKH,GPR37,GRM3,IL12A,INPP5B,VWA5A,AFDN,ADAM22,MT1M,PLCD1,PTPA,MAPK7,MAPK10,KLK6,CNNM2,CNTLN,ZSCAN32,ZSCAN2,TMEM231,GAL3ST4,RGS7,TCP11L1,DZIP1,SLC1A7,SLC20A2,ZNF667,NMNAT2,ARHGAP26,CLASP2,SAMSN1,COBL,SMG6,TCF4,LMF1,WIPF1,KLC2,REEP1,KCNAB1" Drug 4746_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "DPF1,ADD2,AMPD3,AMPH,ANK1,GAS7,PTCH2,ADAM23,LDLRAD4,CALB2,GPR37L1,NRXN3,AKAP7,NRG2,ARHGEF10,ATRNL1,INTS1,SPOCK3,AASS,C3orf18,MTSS1L,FOXG1,PRELID3A,FYB1,CHL1,GAP43,SRCAP,RUNDC3A,GLS,GNG3,RAPGEF1,GRIN1,GRM1,IRAK3,ITGA7,KCNMA1,MEF2C,MOBP,MSR1,MYH7,KCNK10,PCDH8,MAPK7,MAPK10,PTN,C1orf54,PNMA8A,TCP11L1,KCNIP1,SLA,RPH3A,SLC2A5,LIMS2,LIMCH1,TCF4,TGFBR3,THRA,TPM3,STMN4,SLC17A7,ITM2C" Drug 4360_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ADORA3,ADRA1D,SYT13,OGT,APBB2,GAS7,CALB1,CLDN10,GPR37L1,RCBTB2,JAM2,QKI,SULT4A1,DOCK4,DAPK1,SPOCK2,CTIF,CNIH3,ATN1,ELAVL3,APC2,RASL12,FYN,GNAO1,NXPH3,PTGDR2,HLF,IRF8,KCNB1,KCNH2,VWA5A,MAN2A2,MSI1,PALM,POU6F1,PPARA,CEP41,PNMA8A,SH3BP2,SLA,SLC1A7,RIMS1,ZNF423,ATP10B,MAPK8IP3,SYT11,SYN2,WSCD1,ZEB1,TIMP4,R3HDM1,AMOT,UCHL1,CLIP2,MKRN3,NT5M,SCG2,PAK5,TIGD6,DPF3,AP3B2" Drug 6655_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ADRA1D,AP2A2,FAM135A,MRTFA,SEMA7A,KCNAB2,APBB2,APC,DDX3Y,ATM,ATP2B2,RGS11,CFLAR,CALB2,HIP1R,CHGA,CRY2,ARHGEF10,SV2B,DUSP9,SEMA3D,ING4,EPHB1,STX2,IGSF6,F5,KAT8,POLR1B,FOXG1,C1orf61,AFF2,SORBS1,PDLIM5,B3GAT1,ADAM28,GFRA1,PCDH17,GLI2,GRM7,KLF12,KCNJ5,AFDN,OPRL1,PDE4D,PENK,CDIP1,DCHS2,ZSCAN32,NKAIN1,RASA3,DOCK10,SLA,SLC11A1,SNCA,PCDHA5,TRH,FLRT2,SPHK2,REEP1,WNK1,PRDM2" Drug 3817_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "PLA2G6,SEMA6A,LTBP4,AMPH,ANK3,APAF1,APC,AQP6,ASPA,ADGRB3,CACNA1G,C5,CDK5R2,INA,CHI3L2,NRXN3,ABCG1,SNCAIP,MAGI2,TRAPPC9,ATN1,DTNB,ABCC9,EDIL3,EDNRA,MBNL2,ETV1,PIPOX,CEND1,NRN1,FGFR1,SIGLEC8,SRCAP,CNTRL,GRM2,GRM8,SOX21,CELF3,HLF,C2orf72,KCNN1,VWA5A,KITLG,MOBP,ADAM22,NF1,NPTX1,NRCAM,P2RX7,PDE2A,POU3F2,RGS10,CNKSR2,LIMCH1,MAPK8IP3,CHST8,TMOD1,CADM1,FLRT2,ZNF225,PHTF2" Drug 4324_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ASPHD1,ACHE,ADCY2,AMPH,PKP4,PPP4R4,ADAM15,BAIAP3,CHM,CREM,PDE4DIP,C2CD2L,SMG7,DTNA,DTNB,ECM2,LRRC17,FGF1,FGF12,FOXF2,OGA,TRAF3IP2,SOX21,DHX35,ITGA7,KCNB1,KCNJ5,MGAT3,MOBP,MT1M,NTRK2,NTRK3,OPCML,PAK3,PFKFB4,PROX1,PTAFR,CCDC40,ATG16L1,RASGRF1,RGS4,MYH14,GSTCD,CCDC102B,STUM,RASA3,SH3BP2,ZNF667,RIMS1,SP4,ZBTB43,CEP68,JMJD6,ATP11A,DMXL2,TIMP4,CBX5,TPM3,SF1,NT5M,KCNAB1" Drug 4547_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ACTN2,MRTFA,APBB2,MARK4,PTCH2,BRINP2,SLC4A4,NRP2,ST3GAL5,CAPN3,CBFA2T2,SCARB1,SEPT7,CACNA2D2,CHI3L2,B4GALT6,EPS15L1,SLC4A7,TCEAL2,RGS6,ABCC5,EDN1,SGK2,NRN1,ST3GAL6,ZNF589,FOXG1,SORBS1,GPD2,PRUNE2,ATXN2L,ELOVL5,ICA1,ITIH2,JAK2,KCNN1,KIF5C,LIG4,MDFI,MGAT3,MOBP,NF1,PDE4B,PDE4D,PDGFRA,SPATA6,PTPRN2,MARCH1,KHDRBS2,TMEM206,SLN,ZNF415,PDZD2,BEX1,LHPP,DOCK9,TPM2,VGF,VIPR2,PRDM2,PARP6" Drug 5769_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ASPHD1,GRAMD1B,NME5,ANK2,CDC14B,PRX,KIF1A,ADGRB2,BMP7,BTRC,CA12,CLDN10,SCARB1,MAGI1,HOMER3,WHRN,RIMS3,SPOCK2,HS3ST2,CDON,DTNA,EDN1,MBNL2,TNK2,EPB41,COQ7,ZNF549,ARMCX1,KIAA1109,OLFM1,FOXG1,FAM49B,PADI2,HTR2A,SHISAL1,MAPT,AFDN,MMP16,NEUROD1,PDE2A,PDE4D,GPR85,MAPK8,VPS13C,PTHLH,CCDC40,RAD52,SEC61A2,CARF,PPM1E,DZIP1,SLC12A4,SLC15A2,SP4,VAMP1,PLCB1,DOCK9,RALYL,CDK20,TRO,EVI5" Drug 6607_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "SLC12A5,ALK,APBB1,PRX,N4BP2L1,BACH1,FUBP1,CACNB4,CAMK2B,CDH10,PDE4DIP,ERC2,RIMS2,SPOCK2,MFAP3L,SMG7,SV2B,SGK2,ELN,LRRC17,RASGRP2,DLC1,AGAP2,GABRA2,ERAP1,SIGLEC8,CSDC2,RUNDC3A,POLL,PRUNE2,GRIK5,GUCY1A2,PADI2,ELOVL5,KCNC1,KCNN1,KIF5A,KIT,LAMA2,MAP4,MBNL1,MMP16,PALM,PLXNB1,PTN,PTPRB,KCTD17,KCNIP2,FOXRED2,IL17RB,FRMPD1,ASAP3,SLC6A9,SNCA,SPTAN1,ATP10B,TCF4,SZT2,HIRA,PARP6,KCNAB1" Drug 4372_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.84E-08 2.37E-03 2.43E-06 2.77E-05 61 196 "ADCY2,CDC42BPA,APAF1,ARSE,CHRD,ADGRB3,SCAPER,BAIAP3,SLC16A4,SEPT7,KCNAB3,SULT4A1,CNTN1,PCYT1B,VCAN,ARHGAP24,SPOCK2,ELMO1,KLHL3,EDNRA,SGK2,FRY,EN2,ERBB2,F5,ZNF589,SORBS1,PDLIM5,RASL10A,RUNDC3A,ELOVL5,KCND3,KIF5A,LAMA2,LIFR,MMP17,MYT1,PIK3CD,PLCD1,PURG,CEP41,ZNF493,TRIM68,EMID1,KCNIP1,SLC1A7,SLC6A9,RBM34,IZUMO4,NCDN,TCF4,TCF7,HIF3A,PRMT8,HIRA,WIPF1,EMSY,KCNAB1,PLSCR4,HRASLS,SSPN" Drug 5764_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.03E-08 2.47E-03 2.53E-06 2.87E-05 58 183 "NR0B1,AMH,APBB1,APBB2,APC,GAS7,KIF1A,BMP7,IL33,CACNB2,MAP7,PLEKHB1,WHRN,CREM,AKAP12,CRMP1,PHF14,CTH,RIMS3,PITPNC1,CDKL3,PTK2B,FOXG1,TACC2,SYT17,GDF9,GPM6A,GRM2,ATXN2L,KLF12,ITPKA,KCNN1,NPY,SNTG1,PDE4B,PDE4D,SMOX,PMP22,FA2H,LRRN3,PPP5C,PTHLH,PID1,RBBP6,RGS4,RGS10,NLGN1,PPP4R3A,SLC15A2,IQSEC2,TBCEL,DNAH7,R3HDM1,CHST5,TRPC1,TUBB1,VAV1,GAN" Drug 6736_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.06E-08 2.48E-03 2.54E-06 2.89E-05 55 170 "DPF1,ABAT,ADRB2,NME5,APAF1,EPB41L5,ARNTL,BRINP2,NOL4,ST3GAL5,HIP1R,USP2,REPS2,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,PLPPR4,SRGAP3,EFNA3,RGS17,CEND1,TUBB4A,TAOK3,BAIAP2,SORBS1,OGA,FYN,GLS,GUCY1B1,BACH2,DIPK1A,KIF5C,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,SYTL2,ENOX1,RGS4,SH3GL3,CPEB3,DOP1A,TNIK,THSD1,ELOVL4,RGL1,SYT11,SYT1,COBL,DNAJC12,SLC17A7,PLSCR4" Drug 5238_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.27E-08 2.59E-03 2.64E-06 3.00E-05 60 192 "NME5,APC,ASPH,ATP2B2,USP2,CBFA2T2,SOCS6,LHX2,WHRN,SDC3,GIT2,RUSC2,SPOCK3,CDON,RCAN1,MBNL2,EGR3,VPS13B,DMTN,DLC1,FGFR1,CAMSAP1,FHL1,GAP43,TMEM8B,LYVE1,RUNDC3A,GUCY1A2,JAK2,KCNK2,KPNA5,MAPT,ADAM22,NEUROD1,NF1,NTRK2,SNTG1,SERPINE2,LRP12,TNPO2,SAMD9,PTHLH,ZMAT4,RET,TCP11L1,SGK1,SH3BP2,SYBU,KDM4B,EMC1,INKA2,MAPK8IP3,RGL1,PLCB1,ARC,ROBO3,WWC1,AHCYL2,TPD52,SEMA3B" Drug 1284_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.27E-08 2.59E-03 2.64E-06 3.00E-05 60 192 "ABHD6,BIN1,APBB2,APC,APP,SLC4A4,BCL2L2,ST3GAL5,SCAPER,SGCE,HIP1R,KYAT1,CBFA2T2,CLGN,ZFYVE9,NMT2,FEZ1,PDE4DIP,SLITRK5,DZIP3,DOCK4,RIMS3,DNAJC6,SV2A,TSPAN5,PLXNC1,LPAR6,EPB41L2,EPS8,EXTL2,FGFR1,IFI16,ITGA7,KIF5C,MAP4,MEF2C,NCAM1,SLC25A23,PMP22,SIDT1,SATB1,ITSN1,ANKRD6,ELMO2,ZNF667,PALLD,KDM4B,WDTC1,CEP68,RGL1,STXBP1,ATP11A,DNMBP,CAMSAP2,TCF4,ARHGEF12,ATP13A2,TPD52,TRIM9,EMSY" Drug CID003036959 PDEs Stitch 5.55E-08 2.72E-03 2.78E-06 3.16E-05 42 116 "ADCY5,ADCY6,ADCY8,ADRB2,PDE8B,ALDH7A1,CALM1,KRIT1,LRBA,CHGB,AKAP7,AKAP6,AKAP5,CREM,CREB5,ABCC5,TUBB4A,PPP1R1B,AKAP3,DISC1,GNAS,RAPGEF4,GUCY1A2,GUCY1B1,MAP4,NPPA,NPR2,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,EXOSC10,PRKACB,MAPK7,ZNF106" Drug 3046_UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.74E-08 2.81E-03 2.85E-06 3.24E-05 59 188 "SYT13,ANK2,DNAH17,AZGP1,MPDZ,CACNA1G,CD86,CBFA2T2,CD38,SOCS6,CHN2,COL9A3,NRG2,CREM,AATK,ARHGEF10,SUSD5,SIPA1L1,VCAN,PPP1R16B,NOS1AP,DOCK4,DRD1,DYRK1A,HEYL,ING4,KIAA1109,BAIAP2,TRAF3IP2,GALC,SIGLEC8,RUNDC3A,PCLO,RASSF8,HNMT,KCNC1,MEF2C,MMP16,NDP,NTRK3,OLR1,SMOX,MAPK7,BCAS3,BEND5,RGS12,NUDT11,MYH14,SCN8A,CNKSR2,ZC3H13,CDK19,PLCB1,TACR1,PCDHGA1,RUNDC3B,TRPS1,FLRT2,LMF1" Drug 4616_UP Bisacodyl [603-50-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.74E-08 2.81E-03 2.85E-06 3.24E-05 59 188 "AMPH,KCNAB2,PPP4R4,B3GALT2,KSR1,SYNJ1,CA4,CA8,CDH8,ARHGAP33,DLGAP1,SOCS6,CRMP1,CRYBB1,CTH,RIMS2,DCC,DRP2,DTNA,ABCC9,EDNRA,EN2,EPHB1,AGAP2,SEMA6C,PRELID3A,CHL1,SIGLEC8,GNG4,GPD1,NR3C1,VSIG4,ELOVL5,KCNC1,KCNJ4,MBNL1,MSR1,NF1,PDGFRA,CAMKV,STRN3,RGS12,EMID1,RTN1,SCN2B,CNKSR2,SLA,KANSL3,SNCA,ZBTB43,PHLDB1,ARC,SYT5,ANKRD12,RUNDC3B,VAV2,VGF,VIPR2,ZIC3" Drug 6143_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.74E-08 2.81E-03 2.85E-06 3.24E-05 59 188 "ADD3,BIN1,ANK2,APBB2,SYNJ2,SGCE,CACNB4,HIP1R,MAP7,KYAT1,CDH2,CDO1,CHN2,LHX2,DNAJB5,FEZ1,NCAN,PDE4DIP,ZNF337,RIMS3,DNAJC6,DUSP9,MAMLD1,FAM13A,ETV1,TLR7,FGFR1,BAIAP2,CAP2,GPR153,NSG1,DIPK1A,KIF5C,MPP2,NCAM1,NRCAM,SERPINI1,SIDT1,TTLL7,WLS,SH3BGR,SLC1A3,SNCA,PALLD,DOP1A,TNIK,ZC4H2,STXBP1,WSCD1,ZEB1,TRIM2,ICAM5,TPM1,TRPC3,FLRT2,VAV2,TRIM9,SH3GLB2,ACTR3B" Drug CID000002951 Dantrolene-13C3 Stitch 5.78E-08 2.84E-03 2.85E-06 3.24E-05 49 145 "AGT,AK2,APOC2,ATP2A2,CACNA1I,CACNA1G,CA4,CA8,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CACNA2D2,DMD,HIPK3,CACNG7,CACNG3,CACNG2,CAMKK2,GALR1,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IL12A,MAG,NBL1,NOS1,PIK3C2A,PKD1,PYGM,QDPR,RYR1,RYR3,TPCN2,CA14,RTN4,NUP214" Drug 4415_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "NME5,AMH,AMPD3,BIN1,APBB2,APP,RGS20,PDE8B,MARK4,ASPH,ALDH7A1,CFLAR,LDLRAD4,CBFA2T2,RCBTB2,DNAJB5,PICK1,SH2B1,CRY2,CSF1R,RIMS2,SPOCK2,ZNF804A,RUSC2,HSD17B14,EN2,STX2,ZNF589,FGF12,SRCAP,C1QL1,GLS,POLL,RASSF8,ATXN2L,KHK,KPNA5,MAP4,MIA2,MOBP,MSI1,ZNF862,NFYA,NPR2,MAPK7,FAM120C,NKAIN1,C1orf54,RGS10,RPH3A,RBM34,SPTAN1,MAPK8IP3,ARC,ROBO3,CRTC1,FLRT2,VLDLR,SPHK2,HPS4,SLC17A7" Drug 5905_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SLC12A5,SEMA6A,LTBP4,APLP1,CADM3,N4BP2L1,CACNA1D,INA,CRLF1,SULT4A1,RCHY1,RASSF2,HSD17B14,RASGRP2,CEND1,CACNG3,FCGRT,KIAA1109,FGR,GABRA2,GAP43,CPLX2,RAB30,STON1,GRM1,SHISAL1,KCNJ4,KCNQ3,LSS,BCO1,NCAM1,NTRK3,KCNK10,PALM,PCDHGC3,PLTP,MAPK10,GRAMD1C,RFX2,RFX3,KCTD17,TTLL7,ZFHX4,MYH14,PNMA8A,KCNIP2,SEMA6D,RASA3,SLC1A7,TNIK,NMNAT2,ZNF423,TMEM151B,HEY1,SEZ6L,TRPC1,TMPRSS5,VAV2,KCNK12,SLC17A7,MVB12B" Drug 3063_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SPARCL1,SEMA6A,BIN1,AQP4,CCDC181,ATP2B3,SLC2A11,RGS11,SYNJ2,CDH10,DLGAP1,CHI3L2,JAM2,TAOK2,ZFYVE9,FAM149A,RGS6,PDE4DIP,RIMS2,DCC,DRD1,HEYL,SRPK3,ELN,EPB41,ARMCX1,DLC1,CHST15,PRELID3A,DKK3,GABRA1,ARPP21,SIGLEC8,ADAM28,GFER,ZNF276,GNAL,KCNC1,KCNJ5,MBNL1,NAP1L2,NPPA,PPP1R1A,PTH1R,RASGRF1,RGS7,SLN,PALLD,SPTB,ATP10B,SSTR2,SYP,DOCK9,ATP13A2,TGFBR3,TK2,TRO,TUBB1,FLRT1,VGF,KCNAB1" Drug 5242_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADORA1,KIDINS220,ANK1,CADM3,ADAM23,ADGRB3,KSR1,CACNG1,CLCN4,AKAP7,AKAP6,COL9A3,OSBPL3,SDC3,DCAF4,CTIF,BRINP1,DMPK,SIDT2,EFNB3,TENM1,ELAVL3,TNK2,HSD17B14,MTSS1L,KIAA1109,FOXF2,AFF2,GFER,PCDH17,C1QL1,POLL,GPD2,GRIK5,VSIG4,KCNH2,LSS,KITLG,ADAM22,MYT1,NEFM,CLDN11,TMOD2,PLP1,SAMD9,CCDC40,RASGRF1,KLHL11,S100B,SNAP25,SNCA,ZSWIM8,MAPK8IP3,VAMP1,SYT5,DMXL2,TLL2,HEY2,PIK3R5,CHST5,PLSCR4" Drug 4137_DN Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ASPHD1,NME5,AK2,LTBP4,BIN1,APBA2,APBB2,PDE8B,NCOA1,C5,CACNA1D,EPS15L1,C2CD2,SIPA1L1,HDAC4,TBC1D5,C2CD2L,KBTBD11,DTNA,EFNA3,EGR3,LRRC23,ATP8A1,KAT8,FHL1,GPR19,GRB10,SPACA9,ITIH2,ITPKB,KCND3,KLC1,MAP4,MBD1,MPP2,ADAM22,NEK1,SETD4,RETREG1,TMEM104,ZDHHC14,TCP11L1,SEMA6D,SH3BP2,ITSN1,PPM1E,SHANK2,KDM4B,WDTC1,ZHX3,TROVE2,JMJD6,ATP11A,KAZN,MCF2L,CLASP1,PSD3,AHCYL2,PARD3,WRN,ZIC1" Drug 3062_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "LGR5,ASCL1,ATP2B3,B3GALT2,CACNA1G,USP2,SLC16A4,LARGE1,CHGA,SOCS6,DNAJB5,AKAP6,NRG2,CRYBB1,CHD5,PDE4DIP,BRINP1,ST8SIA3,EDN1,AASS,EPB41,ZNF549,CACNG2,BAIAP2,B3GAT1,GABRA1,GNAL,HNMT,HPCA,SCIN,KCNC1,KCNH1,KCNJ3,KCNMA1,MAPT,MATN2,MYH6,MYT1,PCSK5,PMP2,SEPT4,PPP2R2B,PTPRB,NUDT11,ST8SIA1,SLC6A9,SLC11A1,SOX10,ATP10B,TAC3,TBCEL,TIAM1,RIMBP2,TRIO,TRO,LMF1,VSNL1,KLC2,KCNK12,MAP3K12,DNALI1" Drug 3039_UP Equilin [474-86-2]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ABAT,ASCL1,CCDC181,HAP1,INA,DGKI,CDH10,PLEKHB1,AKAP6,TCEAL2,ARHGEF10,DZIP3,RIMS2,RIPOR2,SNPH,INTS1,BRINP1,DCT,MAGI2,TMCC2,ABCC9,CHST15,OLFM1,CAMKK2,GPR153,GALC,B4GALNT1,TMEM8B,SIGLEC8,MYOZ2,RUNDC3A,GRIK5,GUCY1A1,SCIN,KCND3,AFDN,NOVA2,OPRL1,PDE4D,PRPH,RELN,RAB3IL1,MYH14,SEMA6D,SCN7A,SLC1A3,PKNOX2,SLN,IZUMO4,ZC3H13,ARHGAP26,SPTB,MAPK8IP3,TAC3,DNMBP,TBCEL,TGFBR3,TIAM1,ICAM5,SEZ6L,TRO" Drug 4742_UP Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "RALGAPA1,ASIC1,AP2A2,ALCAM,AMPD3,OGT,APBB2,BCAS1,SLC16A4,CHM,TPP1,HAPLN1,AATK,CSF1,ARHGEF10,SPOCK3,HIPK3,EGFR,APC2,FUT9,OGA,C1QL1,MALT1,GNG3,GRM2,GSN,KLF12,TJAP1,KCND3,MDM4,BCO1,PCBP3,PFKFB2,PPARA,PPP5C,RELN,ELOVL2,ZSCAN32,C1orf54,ZNF493,TRIM68,EMID1,ZNF415,KDM4B,RBM26,SPART,MAPK8IP3,FAM168A,SEMA4A,TBCEL,ZEB1,SZT2,DOCK9,AHCYL2,TMOD1,TNS1,LAT2,ZIC3,ITM2C,PHTF2,NUP214" Drug 5450_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "AMPD3,APBA2,KCNAB2,GAS7,SEMA4G,RGS20,RASL11B,ATP6V0A1,LDLRAD4,CACNA1D,ADGRG1,LY86,CRMP1,CSF1,JAKMIP2,DMD,SLC12A6,ECM2,ING4,EN2,STX2,ERCC2,EFS,CEND1,ZNF589,AGAP2,KHDRBS3,GFER,GNAL,GNG3,GPR22,GRB10,NR3C1,ICA1,INSM1,MAN2A2,MAP4,MAPT,MEF2C,MYO7A,NDP,SLCO1C1,CLDN11,PDE1C,CDK14,CDIP1,PTN,RGS12,RPS6KA2,SEMA6D,ZNF821,PPP1R9A,HKDC1,FAM214B,IQSEC2,SZT2,DICER1,XRCC4,WNK1,SLC17A7,KCNAB1" Drug 1510_UP Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SYN3,KIDINS220,MARK4,SYNJ2,CAMK2B,HIP1R,ARHGEF1,ARHGAP33,SOCS6,LHX2,ZFYVE9,DNAJB5,QKI,CNR1,SNCAIP,SPOCK2,MFAP3L,EFNB3,C3orf18,HSD17B14,NRN1,ZIC4,DLC1,FGF12,NEU3,GLS,GRM3,HRH3,INPP5B,JAK2,MOBP,ADAM22,CDK18,GPR85,PFKFB2,TNPO2,PPP5C,PRPH,RELN,CNTLN,PTPRB,ZSCAN2,RAB3IL1,FAM184A,GAL3ST4,KCTD17,MYH14,CARF,KCNIP1,FRMPD1,PKNOX2,SLN,SOX10,ERC1,INKA2,TBCEL,HEY1,TMOD1,PIK3R5,CDK20,PLSCR4" Drug 2553_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "KIDINS220,NR0B1,C1QTNF1,SRPX,BIN1,B3GALT2,CADM3,CFAP410,CALB1,THSD7A,TMEM257,CLCN4,STOML1,TMEM59L,ABCG2,NRG2,RGS6,CSNK1E,MFAP3L,MAGI2,KLHL3,HS3ST2,EDN3,OPTN,ERBB2,CDKL3,GABRA2,GAD1,GALR1,SIGLEC8,ADAM28,PCDH17,GNAS,GRM1,PRDM5,GUCY1A2,GUCY1B1,KLF12,KCND3,TAGLN3,MYBPC1,NNAT,KCNK10,PLCD1,PPARA,DOCK10,SLC1A3,PKNOX2,IZUMO4,ATP10B,TROVE2,ACSBG1,ARC,SYT1,SYT5,ICAM5,SEZ6L,TRO,FLRT1,KCNK12,KCNAB1" Drug 3117_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ABAT,GRAMD1B,OSBPL1A,ALK,CDC42BPA,ANK3,CCDC181,CACNB2,CAPN3,HIP1R,CHN2,CREM,PDE4DIP,ARHGEF4,ECE2,MFAP3L,CDON,HEYL,VPS13B,ETV1,DLC1,FGFR1,IQCG,GPR153,GAD2,ERAP1,GCNT2,ZNF276,GPD2,GPM6A,ADAMTS13,GRIK5,GUCY1A2,PADI2,KLF12,KCNMA1,KCNN1,KCNN3,CD200,NRCAM,PBX1,PDE1C,POU6F1,PPP2R2B,PRKAR1B,MAPK8,GAL3ST4,ROM1,MRAS,PEX26,CXXC4,SNCA,IZUMO4,RAP1GAP2,TAL1,WWC1,TMOD1,TUBB1,SYNC,SCG2,PAK5" Drug 6622_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ACHE,ADD1,PLA2G6,APAF1,APBB2,BRINP2,ADAM15,FUBP1,RUNX1T1,SOCS6,CHRNB2,JAM2,CTNND2,KIAA0753,DLG3,DTNA,HIPK3,ELAVL3,ZNF589,FGF1,FAM49B,ZNF276,GLYR1,MDFI,KITLG,NPR2,CLDN11,PALM,PBX1,RETREG1,NLE1,SPATA6,TNPO2,PPARA,PPP5C,CEP41,PRPH,CCDC40,RAD51D,RASGRF1,RNASE1,STUM,ASAP3,PKNOX2,SHANK2,TNIK,HECW1,ZC3H13,TSPYL2,CEP68,PHLDB1,TBCEL,TCF4,TEX15,ZFPM2,ICAM5,DAAM2,VAV2,ZNF24,WNK1,PARP6" Drug 5787_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "KIDINS220,PLA2G6,FAM135A,APAF1,BSN,CACNB2,INA,CDH10,FOXN3,CHI3L2,CLCN4,IFFO1,SEC14L5,TOX,SPOCK2,SEMA3D,EGR3,PLXNC1,EZH1,ATP8A1,KIAA1109,SEMA4D,AFF2,GABRA2,GATM,GLYR1,GPM6B,GRIK2,GRM1,CELF3,KCNA2,KCND3,AFF1,NEFH,NPTX2,NTRK2,CNNM2,TMEM104,PTN,PID1,ENOX1,RGS4,KCTD17,SEC61A2,SUPT20H,DZIP1,SLC1A7,SLC8A1,OGDHL,ZNF415,EMC1,SPP1,IQSEC2,NPAS3,HIF3A,TF,BHLHB9,TRO,VAV1,SPHK2,KCNAB1" Drug 2161_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADD2,BEGAIN,BIN1,RASL11B,ALDH4A1,GYG2,CA12,THSD7A,CD86,COL9A2,CREM,SH2B1,CREB5,DAPK3,DBT,GSDME,SPOCK3,ST8SIA3,EDNRA,EEF1A2,EFS,CDKL3,TBC1D16,BAIAP2,SCARA3,TMEM8B,ALDH1L1,ADAM28,GFER,RND1,PCLO,GRIK5,GRM1,PADI2,SCRG1,ITGAM,ITIH2,KIFC3,MAP4,MN1,MSR1,SAMD14,ZNF862,PPP5C,MAPK7,PID1,ZCWPW1,RGS12,KLHL11,ZFHX4,SYNDIG1,SMTN,SPTAN1,LHPP,SYN2,OBSL1,RUNDC3B,ZKSCAN5,FAM155A,UGT8,VAV2" Drug 6583_DN STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "APLP1,APP,ADGRB2,CFLAR,WASF1,FOXN3,CLCN4,CNTN1,ARHGEF10,DCAF8,KLHL3,PHF20L1,SEMA4D,TRMO,ATP2C1,FYN,DENND2A,GAD1,SYT17,GHR,GNG4,CACFD1,HNMT,IFI16,IL6R,KIF5C,NDP,PBX1,CDK18,CCSER2,PTCH1,PTPRN2,SH3TC2,FAT4,MSANTD2,MAPK12,SBF1,ZNF821,ASAP3,FHOD3,SLC4A3,PEX26,ARHGEF40,KBTBD4,RAP1GAP2,THSD1,KAZN,IQCE,TRIM2,SZT2,PSD3,THRA,TIAM1,TK2,TPD52,TPM2,LMF1,XRCC4,SPHK2,EPM2A,ACTR3B" Drug 4142_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "TKTL1,NDRG2,ADORA1,LTBP4,CNTNAP1,APOC1,MARK4,BRINP2,CALB1,RUNX1T1,FADS2,CRMP1,ARHGEF10,VCAN,SDC3,RASSF2,SPOCK3,HS3ST2,ATN1,ING4,PIPOX,CAMSAP1,FOXG1,GAD1,ERAP1,DISC1,GPD2,GPR22,GRB10,KLF12,DHX35,IL6ST,IL11RA,KCNMA1,MAP4,MPP2,ADAM22,TAGLN3,NELL2,NNAT,PRKAB2,MAPK8,PLPPR1,ZMAT4,RPS6KA2,BCAN,SNAP25,ZHX3,IQSEC2,RBM26,THSD1,AJAP1,PRRC2C,ATP11A,EXOC7,TBCEL,SMG6,WSCD1,TNS2,DAAM2,TNS1" Drug 7484_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ARID1A,BEGAIN,APC,APOC1,SLC4A4,BMP7,SYNJ2,MTMR3,CHN2,TAOK2,NRXN2,NMT2,QKI,CREM,ENTPD4,PDE4DIP,INTS1,DNAJC6,CDON,DSCAM,DTNA,DUSP9,E2F5,PDLIM5,GPR153,TXNL4A,GLRB,GNG4,GRB10,ADAMTS13,RNFT2,ATXN2L,IL6R,MAN2A2,MDM4,KITLG,MKLN1,MPP2,BCO1,ZNF862,NTRK2,PDE4A,SLC25A23,SMIM7,MINDY2,MAPK8,PRODH,WDR25,RAB3A,RAD51D,ATG16L1,FBXW7,ANKRD6,SMARCD3,ZHX3,LMO3,FAM168A,PLCB1,TACC1,TNS2,MAP3K12" Drug 1503_UP Metronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SYN3,C1QTNF1,SPARCL1,LTBP4,BIN1,PPFIA3,APP,ARHGDIG,ALDH4A1,SCAPER,LDLRAD4,NFS1,CCNT1,SEPT7,CRLF1,SOCS6,SNCAIP,C2CD2L,DTNA,ING4,LRRC23,NCALD,RRAGB,F3,F5,IQCG,ZNF44,AHDC1,GLYR1,VWA5A,MBD1,NACA,NAP1L2,RETREG1,EPN1,PACSIN1,MAPK8,PRODH,PTCH1,ROM1,KCNIP1,ASAP3,ANKRD6,PEX26,PPP4R3A,OGDHL,MAPKBP1,FNBP1,ELOVL4,ARHGEF9,SEMA4A,MCF2L,TCF7L2,TMEM121,CHST8,TK2,TMOD1,TPM1,MICAL1,MAP3K12,HPS4" Drug 5060_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ALK,AMH,APOC1,ASTN1,ATP1A3,KSR1,CACNG1,CACNA2D2,WHRN,MYRIP,PDE4DIP,TRAPPC9,DUSP9,EDN3,SIDT2,PTK2B,GAB1,ERAP1,SYT17,GFER,PCDH17,GNG4,GPR22,GRIK5,GRM1,GRM7,FAM107A,PTGDR2,IL6R,KCNMA1,VWA5A,MAPT,MATN3,MYCN,NUMA1,LRRN3,PRKAR1B,MAPK7,PTPRB,PTPRH,PID1,RASGRF1,RGS10,FBXW7,TCP11L1,KCNIP2,IL17RB,DOCK10,SLA,SLC2A5,ZC3H13,COBL,TRIM2,SLC44A1,SEZ6L,TPM1,RPRM,VGF,WNT7A,ZNF225,WNK1" Drug 3616_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADD2,LTBP4,TRMT9B,BIN1,ATP2A2,ADAM23,ST3GAL5,CACNA1I,CACNA1D,CDH2,NMT2,SULT4A1,CNR1,WHRN,GREB1,HDAC9,ZNF804A,ELMO1,RABGAP1L,TRAPPC9,ST8SIA3,EFNB3,C3orf18,PTK2B,SEMA6C,NSG1,FYB1,HBS1L,CSDC2,RND1,LILRA2,GRM7,ZNF862,FXYD7,NF1,OGG1,OPRL1,KCNK10,PIK3CD,PLCD1,PLCL1,TNPO2,CEP41,PTCH1,ZMAT4,RGS12,RASA3,CPEB3,DOCK10,PKNOX2,SLC6A9,ARHGEF40,HECW1,CDK19,MCF2L2,EPB41L3,SYN2,RIMBP2,TRIO,TTPA,LAT2" Drug 2324_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "LTBP4,AMPD3,APOC1,CDK13,SLC4A4,CACNA1D,CACNA2D2,SLIT2,BAG4,CREM,SDC3,CTNND2,EDRF1,DOCK4,ATN1,DTNA,TOM1,CNNM1,EIF4G2,HSD17B14,FECH,FHL1,FOXG1,ANKFY1,PRELID3A,B4GALNT1,ERAP1,TXNL4A,MSL3,GNG4,SPACA9,GRM7,KCNN1,KCNN2,KIF2A,VWA5A,TM6SF1,NEK1,NUMA1,RETREG1,PRKAR1B,PRODH,CNNM2,ELOVL2,ROM1,EPN2,SLN,WDTC1,SPTAN1,ELOVL4,PLCB1,SYN2,ATP11A,TCF7L2,ZNF34,THRA,VLDLR,ZNF45,REEP1,EVI5,SSPN" Drug 7321_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADORA2A,NME5,PLA2G6,MRTFA,AMH,APBB2,ARHGDIG,CCDC181,CADM3,CACNA1D,CACNA2D2,ARHGEF6,CTIF,TRAPPC9,CNNM1,ING4,C3orf18,STX2,EZH1,FECH,FER,IQCG,ERAP1,NEU3,RND1,TXNL4A,POLL,GNG3,FERMT2,TDRKH,STON1,CNTRL,CACFD1,ATXN2L,TJAP1,MAP4,KITLG,NF1,GON4L,ELOVL2,RAD51D,RAD52,RPS6KA2,SBF1,AMBRA1,SLC22A4,LIMCH1,SNCA,RBM34,INKA2,PHLDB1,PLCB1,MTCL1,ROBO3,ADGRL3,PSD3,AP4E1,ZKSCAN5,EVI5,ITM2C,NUP214" Drug 5072_DN Pizotifen malate [5189-11-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "GRAMD1B,CDC42BPA,MYRF,FOXN3,TAOK2,LHX2,RAB28,SLC4A8,CREB5,HAPLN1,VCAN,DZIP3,RIMS3,GIT2,CNIH3,KLHL3,PARD6A,AK5,EDIL3,EFNB3,EML1,ETV1,SEMA4D,C1QL1,PRRC2B,CNTRL,GUCY1B1,RASSF8,BACH2,HNMT,SHISAL1,INPP5B,ITPKB,KIF5C,MAPT,NDP,NF1,SETD4,PBX1,PLCD1,MAPK7,SYTL2,PTHLH,ELOVL2,ZSCAN2,RAB3IL1,SH3TC2,CCDC25,FAM192A,ATXN7,DZIP1,SHANK2,SLC14A1,BEX1,SPTAN1,ASTN2,CRTC1,THRA,TK2,VIPR2,NDRG4" Drug 3513_UP Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ALK,MRTFA,BIN1,APBA2,APBB2,BRINP2,SCAPER,BTRC,HAP1,CAMK2B,CACNA2D2,ADGRG1,TAOK2,TPP1,FADS2,FAM149A,ENTPD4,SDC3,EDRF1,NOS1AP,ATN1,DSCAM,DTNA,PLXNC1,SORBS3,TNK2,ERBB2,NRN1,C1orf61,EFCAB2,FAM49B,GAP43,RND1,GNAS,NXPH3,ICA1,KIT,AFDN,BCO1,NELL2,NUCB1,PDE1C,PDE3B,LRP12,MINDY2,MAPK10,SAMD9,SNRK,C1orf54,ARID4A,RPS6KA2,SYBU,ZC3H13,SPTB,ATP10B,COLGALT2,PSD3,HEY2,VIPR2,WIPF1,GDPD5" Drug 3698_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADD2,ALAD,FAM135A,PPFIA4,PTCH2,DDX3Y,ATP1A3,N4BP2L1,ADAM23,KSR1,BMP7,GYG2,CACNA2D1,DCLK1,CHRNB2,VAX2,AKAP5,CHD1L,CSF1,PLCH2,CTIF,SRGAP3,EXOG,DTNA,EDN1,FCF1,OLIG2,MTSS1L,FABP7,ANKFY1,SIGLEC8,GLS,POLL,GRIK2,PTGDR2,HSF2,C2orf72,KCNH2,KIFC3,LAMA2,SMAD1,TAGLN3,NF1,OPRL1,CDK18,PIK3CD,MARCH1,RGS12,KCNIP1,AMBRA1,SLC2A5,FAIM2,SOX10,ARC,PCDHA5,CRB1,GPR161,TK2,TRO,EPM2A,NLRP3" Drug 4066_UP Xylazine [7361-61-7]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "LTBP4,PPFIA4,APP,PRX,ARHGDIG,BCHE,KALRN,RUNX1T1,CD86,TAOK2,TPP1,CSF1R,RGS6,LRIG1,MICAL2,CTNND2,RABGAP1L,ING4,PLEKHO1,NCALD,PIPOX,KAT8,AGAP2,PDLIM5,OGA,HBS1L,DISC1,GPR162,STMN2,SPACA9,CACFD1,GRM7,GSTM5,SCIN,KCNF1,LMO1,AFDN,CD200,TAGLN3,NF1,NTRK2,KCNK10,PLCD1,POU3F2,DCHS2,RFX2,KLHL11,MYH14,ASIC4,ZNF821,RASA3,ZNF334,TACR1,KLHL4,PHF24,HIF3A,TNS1,RPRM,VIPR2,UBE3B,DPF3" Drug 5045_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "PDE8B,CADM3,NRP2,BTRC,LY86,PICK1,WHRN,FEZ1,SPOCK2,SV2B,DMD,DTNA,ST8SIA3,OPTN,EFNB3,ELN,CEND1,REEP2,KAT8,GAD2,DISC1,GFER,GNAO1,PRUNE2,GRM7,IRAK3,ATXN2L,KLF12,ITIH2,KCNB1,MSI1,PDE3B,PDE4B,PDGFRA,PFKFB2,SPATA6,PRKAR1B,MAPK10,GRAMD1C,PROX1,RAD52,RGS10,RGS12,MYH14,TCP11L1,RYR1,FRMPD1,CNKSR2,PREX2,SLC11A1,KDM4B,IZUMO4,ATP10B,PHLDB1,ADGRL3,TBCEL,CRB1,PIK3R5,TPM3,REEP1,WNK1" Drug 3930_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "KCNAB2,DNAH17,MARK4,SLC4A4,SLC2A11,ADAM15,CFLAR,CA4,CACNA1A,HAP1,ARHGEF1,CHM,AKAP7,RCHY1,CRMP1,CSF1,MAGI2,CDON,SLC12A6,ATN1,HSD17B14,VPS13B,CEND1,FECH,FGFR1,GAD2,SRCAP,RUNDC3A,GPER1,GRIK5,IL6ST,INPP5B,ITIH2,ITPKB,KCNN1,KCNQ3,KHK,MAN2A2,MDM4,GIT1,ADAM22,NPY,PDE1C,PFKFB2,MAPK8,NKAIN1,SH3GL3,FNDC3A,ZCCHC24,PEG10,SS18,KAZN,EXOC7,PSD3,TMOD1,CDK20,VIPR2,WIPF1,EMSY,SLC17A7,PHTF2" Drug 4502_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ARID1A,ANK1,APOC1,BCAS1,ATP2B2,CADM3,CFAP410,RUNX1T1,NRXN3,STOML1,COL9A3,TCEAL2,NCOR2,ARHGEF10,MICAL2,PDE4DIP,SEC14L5,MFAP3L,EDNRB,CELSR3,MBNL2,LRRC17,CORO2B,KAT8,FGF1,OLFM1,FGF14,FOXG1,ALDH1L1,GPD1,GUCY1A2,ICA1,IFI16,KCNN1,LAMA2,MAP4,GIT1,MT1M,NPY,NPPA,NPR2,PCBP3,NTRK2,RETREG1,CEP41,PTAFR,PTCH1,ELOVL2,PTPRH,KCTD17,MYH14,ROM1,PRR5L,KCNIP1,DZIP1,RBM34,SOX15,KLHL4,CHST5,WIPF1,LAT2" Drug 6811_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SYN3,AP2A2,PLA2G6,C1QTNF1,ALK,PPP4R4,ALDH4A1,SLC2A11,ALDH7A1,BACH1,SCAPER,SGCE,ARHGEF1,CBFA2T2,ADGRG1,COL9A3,ABI3BP,VCAN,CNTNAP2,DCAF4,USP6NL,SNPH,RIMS3,DBN1,RUSC2,RBM12,FABP7,TUBB4A,KIAA1109,BAIAP2,ADAM28,CSDC2,RND1,SPACA9,HNMT,ITGAM,KCNH1,MAOB,MARK1,MIA2,ZNF862,NPPA,PLCB2,CDIP1,POU3F2,RAD52,KLHDC8A,FBXW7,TCP11L1,RPS20,CLIP1,ZNF821,SH3GL3,SPART,ARHGEF9,POPDC3,CRTC1,TUBB1,FAM155A,WIPF1,SPHK2" Drug 6180_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "SLC12A5,ADORA1,KIDINS220,MTUS1,TRMT9B,APBB2,CDC14B,CDK10,PDE8B,BCL7A,BMP7,BTRC,SLC16A4,TAOK2,CLTB,NRG2,NOS1AP,DGKG,SMG7,SGK2,SORBS3,MRNIP,VPS13B,RASGRP2,PIPOX,EXTL1,GAD2,PCSK1N,GRIN1,PTGDR2,HSD17B1,KCNJ5,MAP2,MID1,AFDN,BCO1,NAP1L2,NELL2,NPPA,NTRK2,OPRL1,PTPRN,ROM1,SEMA6D,SH3BGR,PEX26,SLC8A1,SLCO1A2,RAP1GAP2,EXOC7,TCF4,SYNE1,ATP13A2,CHST8,ICAM5,SEZ6L,HIRA,LMF1,SLC17A7,KCNAB1,SSPN" Drug 4570_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ASPHD1,KIDINS220,NR0B1,C1QTNF3,LTBP4,CDC14B,PDXK,ASCL1,ATP6V0A1,BMP7,IL33,CAMK2B,RUNX1T1,USP2,ARHGEF2,ASIC3,ABCG2,FEZ1,PDE4DIP,CNTNAP2,PHF14,RIMS2,DMPK,EDN3,SGK2,HIPK3,CDKL3,ST3GAL6,OLFM1,SEMA4D,GAB1,ZNF44,GAD1,B4GALNT1,ADAM22,MSR1,PDE4D,GPR85,RETREG1,PPP2R2B,PTPRN2,ACSS3,KHDRBS2,SELL,RASA3,FBXO11,SNAP25,WDTC1,TSNAXIP1,KDM4C,ARHGAP26,RAP1GAP2,PCDHGB6,RALYL,SLC19A3,GPR161,TK2,TMOD1,ZNF74,REEP1,DPF3" Drug 5960_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "PLA2G6,ALK,BEGAIN,AMPH,CDK13,DNAH17,ALDH4A1,ADGRB2,BAIAP3,CDK5R2,PLAA,QKI,DAPK3,SPOCK2,AK5,PLXNC1,LPAR6,TNK2,PIPOX,ZNF44,TRAF3IP2,GNG4,PRDM5,PADI2,PTGDR2,IL11RA,IL12A,KCNJ5,MOBP,NEUROD1,NF1,CDK18,NLE1,POLG,POU3F4,MAPK7,MAPK8,PTPRN2,RAP1GAP,RGS10,RGS12,KLHL11,GSTCD,ROM1,STK32B,SELL,HKDC1,SLC2A5,TSNAXIP1,ZHX3,KDM4C,VAMP1,ATP11A,ZEB1,GPR161,VGF,SLC13A3,ZIC3,KCNAB1,MPPE1,UBE3B" Drug 2783_DN Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "NDRG3,DOC2A,APC,APP,ARNTL,CFLAR,SYNJ1,CA12,CACNB2,DNAJB5,HOMER3,PDE4DIP,CTNND2,MAML1,JAKMIP2,DNM2,DTNA,CNNM1,VPS13B,NCALD,KAT8,KIAA1109,FGFR1,SEMA4D,DISC1,ALDH1L1,MALT1,GLYR1,GNG4,RASSF8,AGBL5,MDM4,KITLG,MMP16,NEK1,NOS1,CNOT4,PLCD1,LRP12,ZSCAN32,RAB3IL1,C1orf54,RGS10,RGS12,RNASEL,MCMBP,ANKRD6,SLC6A8,SMARCD3,RBM34,EMC1,TROVE2,STX1A,KAT6B,CDK20,RUNDC3B,TRPC1,VGF,WNK1,PHTF2,SENP7" Drug 4465_UP "estradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ADRA1D,APAF1,KCNAB2,PTBP2,RUNX1T1,CBS,CHI3L2,CHRNB2,RAB33A,DNAJB5,RAB26,AKAP5,PDE4DIP,APPL1,USP6NL,DBT,SPOCK3,CHRDL1,EXOG,EGFR,LRRC23,ETV1,PNMA2,ZMYND11,GAP43,TMEM8B,PCDH17,LYVE1,GLI2,CACFD1,GUCY1A2,NXPH3,IFI16,ITGA7,LAMA2,NPTX2,PALM,CDK18,PDE4B,PFKFB2,NLE1,LRP12,PTCH1,ELOVL2,PTPRN2,FAT4,SLC25A36,SYNDIG1,SH3BP2,SLC15A2,SLCO1A2,HECW1,EPB41L3,MCF2L,SZT2,DOCK9,CDK20,TPM3,HIRA,FLRT2,ZIC3" Drug 4580_DN Beclomethasone dipropionate [5534-09-8]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "ALK,MRTFA,ARHGDIG,BRINP2,ATP1A3,SYNJ2,CACNA1A,CAMK2B,CDC42,TPP1,STOML1,HOMER3,COL9A3,CRY2,CSF1,CSF1R,ARHGEF4,LYPD1,SGSM2,DPH1,DTNA,CELSR3,MBNL2,ING4,TNK2,MRNIP,HSD17B14,EN2,FGFR1,SCARA3,C1orf61,FYB1,GLRB,GPER1,CNTRL,GRM1,IL6ST,KCNJ4,GIT1,CLDN11,PDE4B,FA2H,GRAMD1C,GON4L,IL17RB,ZNF821,DZIP1,ANKRD6,ARHGAP26,LHPP,MAPK8IP3,PDLIM2,ADGRL3,OBSL1,CRTC1,CHST8,THRA,TIMP4,WNT7A,SPHK2,NT5M" Drug 5668_UP Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "AGT,BEGAIN,APBA2,SEMA4G,ARHGDIG,RGS11,RGS9,CALB2,CDO1,FOXN3,TPP1,FADS2,EDRF1,GIT2,MAGI2,ST8SIA3,EGR3,TENM1,COQ7,ERBB2,NRN1,TUBB4A,FGFR1,FHL1,C1orf61,GABRA2,RUNDC3A,RAB30,PCLO,SPACA9,BTN2A1,GSN,TJAP1,KCNH2,KCNMA1,MAOB,TAGLN3,NF1,CNOT4,P2RY1,RETREG1,LRP12,VPS13C,PTX3,CEP97,RGS12,KCTD17,CCDC102B,SYNDIG1,ZFP2,SH3BP2,SYBU,SNCA,IZUMO4,KIAA1107,DOCK9,CRTC1,TEX15,ZNF34,ANKS1B,SEMA3B" Drug 4631_UP Josamycin [16846-24-5]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "TTYH1,ADCY6,SEMA6A,APBB2,CDK10,ASCL1,ALDH4A1,ATP1A2,KSR1,RUNX1T1,SLC16A4,NEURL1,TAOK2,RAB28,AKAP6,MICAL2,PDE4DIP,C2CD2L,EXOG,DRP2,DTNA,SGK2,SIDT2,COQ7,RASGRP2,ETV1,SIGLEC8,RUNDC3A,GLRB,GPER1,GRK4,GRIA1,SPACA9,TJAP1,ITIH2,KCNMA1,KCNN1,PACRG,AFF1,DDX25,CNOT4,NTRK2,CLDN11,PCSK5,POU3F2,SNRK,RFX2,ROM1,SCN8A,FUZ,ANKRD6,ZKSCAN3,OGDHL,ARHGAP26,TROVE2,PHLDB1,PCDHA5,TMOD1,SEZ6L,TRIO,TRPC3" Drug 4737_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.95E-08 2.92E-03 2.85E-06 3.24E-05 61 197 "RALGAPA1,FZD9,PLA2G6,SPARCL1,AMPD3,CDC42BPA,ASCL1,ATP1A2,BAIAP3,CACNA2D1,CHRNB2,SH2B1,RIMS3,SPOCK2,SPOCK3,ATN1,VPS13B,ERCC2,IGSF6,CEND1,KIAA1109,GABRA5,GAD1,SIGLEC8,ALDH1L1,GNG3,GPER1,TJAP1,KCND3,KIFC3,VWA5A,SMAD1,MATK,MMP16,MOBP,ADAM22,NEUROD1,NFIX,SETD4,OPCML,PDE4B,PFKFB2,PLCD1,PTHLH,ENOX1,RFX2,SUGCT,KLHDC8A,TCP11L1,KANSL3,SPART,CAMTA2,AJAP1,ACSBG1,SYN2,PHF24,TRPC1,VAV2,LAT2,PRDM10,TIGD6" Drug CID000016953 thioflavin T Stitch 6.07E-08 2.98E-03 2.90E-06 3.30E-05 48 141 "SERPINA3,ACHE,APAF1,APC,APLP1,APOC1,APOC2,BCHE,CCKBR,CX3CR1,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HSP90AA1,SMAD1,KITLG,OGG1,PAH,ABCB1,PACSIN1,FSD1,MAPK9,MAPK10,PTX3,QDPR,FBXW7,WLS,SALL1,ATXN7,FOXRED1,NLGN1,SLC1A3,SNCB,DDN,SYP,TTPA,ZIC1,SLC30A3,PRTFDC1,NETO1,JPH3" Drug CID000001650 AC1L1BXF Stitch 6.12E-08 3.00E-03 2.92E-06 3.33E-05 34 85 "DGKZ,DGKD,DGKI,DGKB,DGKG,DLG4,EIF4G2,GFAP,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HMGB1,ITGAM,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,MLC1,PLPPR5,SLC17A7,PLD4" Drug 6901_UP scriptaid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.23E-08 3.05E-03 2.97E-06 3.38E-05 58 184 "APLP1,APP,MARK4,BMP7,RAB29,BAIAP3,AKAP12,PDE4DIP,RIMS3,ARMCX2,DNAJC6,OPTN,EFNA3,MBNL2,STX2,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,STON1,KIF5C,MPP2,MXI1,NEK1,PCDH9,PDE4A,SERPINI1,PIK3CD,PKIA,PRPH,PTCH1,RPS6KA2,SH3BGR,SH3GL3,SYBU,WDR47,FAM214B,PKNOX2,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,NPL,RUNDC3B,RPRM,DNAJC12,ZNF23,SLC17A7,ITM2C" Drug 4458_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.33E-08 3.10E-03 3.02E-06 3.43E-05 55 171 "ABAT,ADRB2,ARNTL,MARK4,BRINP2,ST3GAL5,CHN2,NMT2,STOML1,ABCG1,PDE4DIP,CTH,RIMS3,DNAJC6,JAKMIP2,PLPPR4,EDNRA,EFNA3,TUBB4A,ATP8A1,TESK2,BAIAP2,SORBS1,FYN,CYP46A1,RUNDC3A,RND1,GLS,GUCY1B1,KIF5C,VWA5A,LSS,MAP2,PCDH9,PDGFRA,SERPINI1,RETREG1,PROX1,PRPH,RGS4,SH3GL3,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,ACSBG1,SYT11,SYT1,KAZN,RUNDC3B,CADM1,DNAJC12,SLC30A3,SLC17A7" Drug 4650_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.49E-08 3.18E-03 3.08E-06 3.50E-05 60 193 "NME5,ANK3,FAM131A,APOC1,ASPH,LDLRAD4,CANX,SPAG9,CHM,CNOT8,CLCN4,QKI,BAG4,ENTPD4,SLITRK5,EXOG,EFNA3,ING4,PLEKHO1,DENND4A,SCML2,ZNF589,ANKFY1,EML4,NR3C1,HNMT,SHISAL1,DIPK1A,KIF2A,LIG4,NDP,CNOT4,NPR2,PAK3,PLCD1,SNRK,PTK2,PTN,RALGDS,RGS4,ROM1,CLIP1,TRAPPC13,ZNF821,ZFP30,FUZ,FNDC3A,LIMS2,RAB3GAP1,SMARCD3,WDTC1,TNIK,TAB2,SS18,TCF4,ARHGEF12,TMEM121,BHLHB9,UBTF,WIPF1" Drug 2482_UP Tolazamide [1156-19-0]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.49E-08 3.18E-03 3.08E-06 3.50E-05 60 193 "ABAT,ADORA3,ADGRF5,ALK,ANK3,APP,CDC14B,CDK5R1,CFAP410,CDC42,CDH10,TAOK2,RAB26,PCYT1B,WHRN,CABP1,COL9A3,ABI3BP,SNPH,DAPK3,DNAJC6,ELAVL3,FER,NBEA,KHDRBS3,GATM,GNAL,TDRKH,GRIK5,NCKAP1L,ITIH2,KCNN3,MOBP,TAGLN3,MYO6,NEUROD1,NPTX1,NTRK2,PDE2A,PRKAR1B,MAPK7,PRPH,WDR25,MARCH1,RGS3,TTLL7,TCP11L1,SEMA6D,STUM,CNKSR2,SMTN,LIMS2,SLC11A1,SLN,ARHGAP26,TCF7L2,TRIO,ZBTB38,SLC30A3,STMN4" Drug 6100_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.49E-08 3.18E-03 3.08E-06 3.50E-05 60 193 "RALGAPA1,LTBP4,LGR5,PLA2G4C,ATP1A3,GYG2,BAIAP3,LDLRAD4,CFAP410,CLDN10,CBARP,NRXN1,DNAJB5,WHRN,NCOR2,TENM4,CNTNAP2,RIPOR2,INTS1,OLIG2,LRRC23,RASGRP2,CAMSAP1,GPR153,NSG1,GAB1,ERAP1,ALDH1L1,SRCAP,HPGDS,PRUNE2,LILRA2,STON1,NR3C1,GRM7,GSN,GUCY1A2,ATXN2L,KCNJ9,MMP16,MYH7,NOVA2,PCBP3,NTRK2,CAMKV,RETREG1,PURG,LRRN3,TRIM68,TCP11L1,RPS6KA2,ASAP3,RPH3A,CCDC88A,OGDHL,SNCA,TK2,PIK3R5,TRH,TRPM2" Drug 3866_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.49E-08 3.18E-03 3.08E-06 3.50E-05 60 193 "ADORA2A,DOC2A,APOC1,ARRB1,ALDH4A1,CFLAR,SYNJ1,SYNJ2,CA4,CHM,TAOK2,SLIT2,HOMER3,AKAP7,SDC3,CTNND2,RIMS2,ARHGAP32,DAPK3,NR1D2,DTNA,EIF4G1,FAM198B,KIAA1109,PDLIM5,GFER,GLYR1,HTATSF1,STON1,CLASRP,IGSF1,LSS,MDM4,KITLG,ADAM22,NEK1,NF1,NUMA1,PDE3B,PFKFB2,PIK3R1,SLC25A23,MBOAT7,SNRK,PTHLH,ZSCAN2,ENOX1,CARF,TCP11L1,EMID1,PEX26,BTBD7,ARHGAP26,TBL1X,TCF7L2,TRIO,REEP1,SNX27,PHTF2,RNF146" Drug 5600_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.49E-08 3.18E-03 3.08E-06 3.50E-05 60 193 "NDRG2,ADORA1,AMT,APAF1,SEMA4G,CAPRIN2,RAB29,CACNG1,SYNGR3,CLGN,NCAN,RIMS2,RASSF2,ARMCX2,DMD,DYRK1A,FRY,EFNB3,ELN,KIAA1109,PDLIM5,CSPG5,FYN,GAD1,SRCAP,VWA5A,MAOB,MAPT,MDFI,MYO7A,NF1,CDK18,TMOD2,PIK3CD,LRP12,ASAP3,CPEB3,ARHGEF40,SLCO1A2,LIMCH1,SNCA,TNIK,ZCCHC24,NMNAT2,HECW1,ZNF423,SPTB,SPART,ATP10B,ST5,ELOVL4,DMXL2,TRIM2,RPGRIP1L,BEX4,VGF,MICAL1,LAT2,REEP1,SLC30A3" Drug CID000326807 NSC298883 Stitch 6.53E-08 3.20E-03 3.10E-06 3.52E-05 35 89 "SYNJ1,RHBDL1,CLCN3,MYL6B,CLTC,CRMP1,CSF1R,SNAP91,SV2A,DNM1,DNM2,DNM1L,STX2,PNMA2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HMGB1,MYBPC1,MYL3,MYO5A,NTRK2,P2RX7,RAD17,STX1B,SNAP25,STX1A,SYN1,SYN2,SYP,SYT1,SLC17A7" Drug 6939_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.75E-08 3.31E-03 3.19E-06 3.63E-05 57 180 "APLP1,MARK4,BMP7,ST3GAL5,BAIAP3,CRLF1,WHRN,AKAP12,PDE4DIP,DOCK4,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,TMCC2,OPTN,EFNA3,EFNB3,STX2,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,STON1,KIF5C,MXI1,PCDH9,PDE4A,SERPINI1,PIK3CD,RETREG1,PKIA,PRPH,RAB3A,SH3BGR,SH3GL3,SYBU,WDR47,ZCCHC24,SOX15,SPTAN1,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,AGTPBP1,HEY1,BEX4,RUNDC3B,DNAJC12,GDPD5,NAV2,SLC17A7" Drug 6064_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.75E-08 3.31E-03 3.19E-06 3.63E-05 57 180 "DPF1,ADD3,NME5,APLP1,MARK4,ST3GAL5,CDH18,CLGN,WHRN,AKAP12,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,EFNA3,EFNB3,RASGRP2,TUBB4A,DPYSL4,SORBS1,FYN,CYP46A1,RND1,RAB40B,STON1,KCNB1,MXI1,NAP1L3,NEK1,TMOD2,SERPINI1,PIK3CD,GRAMD1C,PRPH,PTCH1,RPS6KA2,SH3GL3,ASAP3,WDR47,SMARCD3,TNIK,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,DNAJC12,SLC30A3,SLC17A7,ITM2C" Drug 3787_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.75E-08 3.31E-03 3.19E-06 3.63E-05 57 180 "ABAT,ABHD6,ADRB2,ARNTL,BRINP2,ST3GAL5,GYG2,USP2,SYNGR3,WHRN,CREB5,ABCG1,LRIG1,PDE4DIP,CTH,C2CD2L,PLPPR4,SRGAP3,EFNA3,RGS17,PTK2B,TUBB4A,TAOK3,BAIAP2,SORBS1,FYN,RND1,STON1,KCNH2,KIF5C,LIFR,MAPT,MMP16,TAGLN3,PCDH9,PDGFRA,ENPP2,SERPINI1,PIK3CD,RETREG1,RGS4,SNCB,TNIK,THSD1,ELOVL4,CEP68,RGL1,SYT11,SYT1,COBL,OBSL1,RUNDC3B,SSBP2,DNAJC12,TRIM9,SLC30A3,PLSCR4" Drug CID006324636 LY341495 Stitch 7.06E-08 3.46E-03 3.30E-06 3.75E-05 22 43 "ADORA2A,BSN,CNR1,FOLH1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,MAP4,RYR1" Drug ctd:D015034 Zinc Oxide CTD 7.27E-08 3.56E-03 3.30E-06 3.75E-05 87 318 "VWA5B2,ADCYAP1R1,UNC79,APAF1,GPAM,ATP2A2,ATP2B1,KIF1A,ADGRB3,BCHE,CALB1,CDC42,CHGA,CHGB,CHRNA4,RAB3C,NGEF,LY86,RAB26,CREB5,CRYM,SV2B,DLG2,EEF1A2,SEMA3D,SPEG,OLFM1,FGF12,FLT1,CPLX2,GDF1,MSTN,ADAM28,GHR,C1QL1,GRIK1,NR3C1,ELOVL5,IGF1,IL11RA,KIF5C,LSS,MAPT,EFHB,MSR1,TAGLN3,NCAM1,NFE2L2,NPY,NPTX1,PCBP3,NRCAM,OPCML,PCSK2,PDE4B,PENK,FTO,MAPK3,ELOVL2,RET,RGS4,ROBO1,AMER2,SCG5,SH3GL2,CNKSR2,SYBU,LRRC55,SNAP25,ATP10B,SST,INKA2,ELOVL4,SEPT3,SYT1,SYT4,SIRT1,TLR4,RIMBP2,TNR,SEZ6L,LRTM2,NPDC1,NDRG4,FSTL5,MFF,SCG2" Drug 4410_UP Captopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ASIC1,ADORA1,PLA2G6,BIN1,APP,AZGP1,CFAP410,CACNA2D1,CAST,RUNX1T1,CDO1,QKI,CNR1,COL9A3,NRG2,NCOR2,DBT,MFAP3L,C2CD2L,TMCC2,ELAVL2,VPS13B,SPEG,DLC1,ZNF589,GAD1,NEU3,GNG3,GPER1,ADAMTS13,GSTM5,IRF8,NF1,CNOT4,NPTX2,PALM,TNPO2,C19orf57,MED1,PTAFR,TRIM68,RGS10,ZFHX4,FBXW7,SEMA6D,ZFP2,LIMCH1,SPP1,BEX1,CDK19,ATP10B,AJAP1,PLCB1,TAC3,HEY2,UGT8,XRCC4,ITM2C,MVB12B,PHTF2,DPF3" Drug 6104_DN Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ADORA1,AP2A2,TRMT9B,AMPD3,AMPH,PDE8B,CFLAR,BTRC,CA4,CACNA1A,CACNA1D,ARHGEF1,CBFA2T2,ARHGAP33,RCBTB2,NRG2,CRY2,PDE4DIP,CTIF,ARMCX2,MFAP3L,DRD1,SORBS3,IRAK4,ING4,ERCC2,CDKL3,F5,DLC1,FHL1,C1orf61,SEMA4D,GAB1,SRCAP,GLS,PRRC2B,RASSF8,MAP4,MID1,MOBP,MPP2,NUMA1,NECAB2,MAPK7,GRAMD1C,PRPH,ZSCAN32,ROM1,RASA3,SH3BP2,SMTN,SMARCD3,KDM4B,SOX2,ST5,MAPK8IP3,STX1A,TBCEL,TMOD1,EMSY,SSPN" Drug 4009_UP Sulmazole [73384-60-8]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "SYT13,AMH,PPFIA4,PKP4,BCAS1,CDK13,SLC4A4,BAIAP3,BTRC,USP2,CDC42,DLGAP2,ADGRG1,JAM2,NRXN3,AKAP5,CRY2,SUSD5,SPOCK2,SGSM2,ABCC9,ST8SIA3,TNK2,RGS17,ATP8A1,KIAA1109,FGFR1,HPCAL4,EFCAB2,OGA,GAB1,LYVE1,GLYR1,GRIA1,PADI2,ITIH2,KCNJ5,KCNK3,KCNN1,LAMA2,ADAM11,TM6SF1,MTRF1L,PPP2R2B,LRRN3,GAL3ST4,PNMA8A,GSTCD,DZIP1,KANSL3,RBM26,COBL,SYT5,EXOC7,SLC44A1,LAT2,SF1,SLC30A3,KCNAB1,PAK5,DPF3" Drug 3307_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ADORA1,MRTFA,APBA2,CDC14B,RASL11B,ATM,BCL2L2,NRP2,CFLAR,ARHGEF7,CDH10,TAOK2,WHRN,CTIF,DMPK,DTNA,SUGP2,PLXNC1,ING4,STX2,SPEG,ZNF589,FGFR1,FHL1,FOXG1,AGAP2,SORBS1,OGA,DISC1,SEPT9,PRUNE2,PTGDR2,IL6ST,MEF2C,MID1,ADAM22,MX1,NDUFA5,NUMA1,CLDN11,PTAFR,RGS12,KCNIP1,ITSN1,CPEB3,BCAN,SLC1A7,CXXC4,ZBTB43,SAMSN1,SS18,ST5,KAZN,KIAA1107,TBCEL,PCDHGA10,TMOD1,VIPR2,DNALI1,EVI5,DPF3" Drug 1499_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ACTN2,NDRG2,C1QTNF1,BIN1,APBB2,APC,BCAS1,PPP4R4,ALDH4A1,SLC4A4,ADGRB2,CDK5R1,GYG2,BTRC,CAMK2G,ARHGAP33,CACNA2D2,TAOK2,RAB33A,SDC3,GREB1,TMCC2,DTNA,MBNL2,EIF4G2,MRNIP,LRRC23,F3,DLC1,KAT8,FGFR1,IQCG,PCDH17,GLYR1,TJAP1,TAGLN3,NACA,NUMA1,PIK3R1,CCSER2,MBOAT7,POLG,ZFHX4,ROM1,EMID1,FBXO11,PPP4R3A,KIF13A,RBM34,SOX10,HECW1,THSD1,ARC,ASTN2,ATP11A,SIN3B,PRMT8,UCHL1,MICAL1,LAT2,NT5M" Drug 3797_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ACTN2,ADORA3,AGT,LTBP4,APAF1,AQP4,ATP2B2,CADM3,ATP6V0A1,NRP2,BSN,SCARB1,TPP1,CNR1,CABP1,CSF1,CSF1R,IPCEF1,SPOCK2,MAGI2,SRGAP3,ATN1,ABCC9,EDNRA,LRRC23,RASGRP2,PIPOX,ABCA8,C1orf61,ALDH1L1,GLYR1,GRM7,PADI2,PTGDR2,ICA1,IRF8,KCNJ4,PNMA3,POU6F1,PROX1,PTAFR,ZSCAN32,ZMAT4,RET,RGS12,KLHL11,SLC1A6,PKNOX2,BTBD7,SLN,SOX2,SOX10,HECW1,MAPK8IP3,CRB1,TNS1,TPM1,FLRT2,SPHK2,PRDM2,KCNAB1" Drug 4095_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "C1QTNF3,CDC14B,CACNA2D1,CAMK2B,CCKBR,SLC16A4,DGKI,CACNA2D2,NRXN3,CNTN1,NCOR2,CSF1R,IPCEF1,ARHGEF4,RIMS2,ST18,SEC14L5,SPOCK2,C2CD2L,SPOCK3,DTNA,EDNRA,SRPK3,IGSF6,CORO2B,FGF1,TBR1,GABRB3,SRCAP,GPR17,STMN2,GRM7,GUCY1A2,HPSE2,KCNF1,KCNJ5,KCNN1,KITLG,NF1,NPTX1,NTRK2,OLR1,PBX1,PLCD1,PMP2,SPATA6,PPARA,MAPK10,RGS4,TMEM206,KCNIP2,ZNF821,NLGN1,SLCO1A2,CXXC4,FAIM2,KLHL4,PCDHGB6,HIF3A,CHST5,CADM1" Drug 6522_UP Azapropazone [13539-59-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "AQP4,ARRB2,ATP1A2,CA4,CALB2,USP2,SLC16A4,CHGA,CLCN4,DNAJB5,AKAP7,AKAP6,WHRN,TCEAL2,TENM4,CNTNAP2,GREB1,SV2A,RCAN1,DTNA,EDNRA,LRRC23,ST3GAL6,FGF13,CAMSAP1,AGAP2,SORBS1,OGA,ZNF44,ERAP1,GFER,GUCY1B1,SLC2A6,AFDN,NEFH,RETREG1,NLE1,PLCD1,NECAB2,POU3F2,PPP5C,SLC6A15,ZMAT4,RGS3,NUDT11,RPS6KA2,FUZ,SLC11A1,RIMS1,ARHGAP26,PHLDB1,JMJD6,PLCB1,IQCE,SMG6,OBSL1,CRTC1,SLC44A1,R3HDM1,SLC30A3,JPH3" Drug 5383_DN Pralidoxime chloride [51-15-0]; Down 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "RALGAPA1,NME5,C1QTNF3,BRINP2,NUMB,CFLAR,BTRC,CFAP410,CA12,SCARB1,SLIT2,ZFYVE9,ENTPD4,ABCG1,TBC1D5,DAPK3,DBN1,SMG7,FEM1B,EFNA3,SORBS3,OGA,GCNT2,GNG4,PRRC2B,SPACA9,GRIK5,HNMT,IL6ST,KCNH2,IPO5,MDM4,MITF,CNOT4,PRODH,PTHLH,ELOVL2,RAB3A,RGS12,ARHGEF10L,CCDC25,EPN2,SLC20A2,SPTAN1,TROVE2,ST5,INKA2,CEP68,VPS13A,MCF2L,PSD3,CRTC1,AHCYL2,TMEM121,AP4E1,SLC44A1,TK2,PLPPR2,ZBTB14,ZNF45,SMIM8" Drug 4004_UP Boldine [476-70-0]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ADD2,SLC12A5,ANK2,APBB2,DDO,CDK13,B3GALT2,N4BP2L1,FUBP1,CACNA1G,BTRC,CCK,CHN2,NRXN3,IFFO1,SUSD5,RIMS2,MFAP3L,DLG2,DRP2,DTNA,ST8SIA3,EDN3,CORO2B,FGFR1,DCTN2,PRELID3A,FYB1,GABRA3,SIGLEC8,MYOZ2,LYVE1,GNG3,GRIK2,GPR45,HSF2,KCND3,KCNQ3,MAG,MOBP,PCSK5,PDE4B,PENK,MAPK10,PROX1,RFX2,LRRTM4,KANSL3,CXXC4,SOX2,UNC5B,ACSBG1,SYT5,ADGRL3,OBSL1,SLC44A1,TPM1,NPL,VIPR2,CAMK1G,NLRP3" Drug 3576_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ASIC1,ALCAM,APBA2,APC,PPFIA3,PRX,PPP4R4,PDE8B,MARK4,ASPH,LDLRAD4,BTRC,CACNB2,SULT4A1,AKAP7,CRY2,NOS1AP,KIAA0586,JAKMIP2,MFAP3L,FBXL5,DSCAM,EDNRA,PHF20L1,SUGP2,SORBS3,CDKL3,ATP8A1,MALT1,TDRKH,GPR22,RNFT2,ATXN2L,ICA1,KPNA5,MAPT,MBD1,KITLG,SCAMP5,NF1,NPTX1,PACSIN1,MAPK7,CNNM2,GON4L,NEK11,ZCCHC24,ZNF423,SAMSN1,STX1A,IQCE,ZEB1,CRTC1,TGFBR3,THRA,TK2,ZMYND8,LMF1,XRCC4,REEP1,EVI5" Drug 5727_UP Dienestrol [84-17-3]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ALDH4A1,NRP2,SYNJ1,BTRC,CACNA1D,KALRN,CAMK2B,BRSK2,MYOM2,CHRM4,NRXN3,HOMER3,WHRN,DCC,DCT,SPOCK3,SV2A,DLG3,PLXNC1,IGSF6,ZNF549,NRN1,FGF1,EFCAB2,GAB1,ERAP1,SIGLEC8,ALDH1L1,SRCAP,GNG4,RAPGEF1,GRIK2,PADI2,KCNJ5,MDM4,MEF2C,MN1,TAGLN3,LYRM9,MYO7A,NDUFA5,NF1,CNOT4,OPCML,PTHLH,ACSS3,ENOX1,RFX2,RGS10,SMPD3,ZNF821,FNDC3A,RBM34,SPTAN1,VAMP1,TACR1,SEMA4A,TCF4,FLRT2,ZBTB14,MVB12B" Drug 7505_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ABHD6,NDRG2,DOC2A,CDC42BPA,ALDH4A1,N4BP2L1,CFAP410,CDH10,FADS2,CRY2,CTIF,MFAP3L,ATN1,DTNA,HIPK3,FEM1B,EFNA3,EGFR,SPEG,VPS26C,EZH1,ZIC4,SCARA3,GALC,SEPT9,EML4,ITPKA,JAK2,IPO5,MMP16,SLC11A2,NUCB1,CCSER2,PACSIN1,POLG,PPP5C,MAPK7,CARF,TCP11L1,SGK1,ASAP3,SLC1A2,PEX26,SLC15A2,SLN,KDM4B,ZCCHC24,IZUMO4,IQSEC2,MAPK8IP3,ANKRD12,IQCE,TCF7L2,TRIM2,CHST8,TK2,BEX4,CDK20,NSD2,ZNF45,MAP3K12" Drug 5457_UP Naproxen [22204-53-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ACTN2,AGT,APAF1,APC,APOC1,ASPH,KSR1,SYNJ2,MTMR3,SGCE,CACNA1D,CDH2,CLGN,TPP1,SLC4A7,CREM,GREB1,MFAP3L,ING4,RGS17,ELN,EFS,RRAGB,FAM198B,DLC1,FGF13,FGFR1,ERAP1,SIGLEC8,GLS,ADAMTS13,NXPH3,ICA1,MAN2A2,MAP4,MOBP,CLDN11,PDE1C,PENK,POU3F4,MAPK10,BSDC1,RGS4,TCP11L1,SH3BP2,CPEB3,SLC1A7,FAM214B,CDK19,ARC,TACC1,DOCK9,CRTC1,CHST8,DAAM2,CDK20,HIRA,PDIA2,XRCC4,SLC30A3,SSPN" Drug 6289_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ALAD,LTBP4,ALK,CDC42BPA,PPFIA3,PDE8B,ZSCAN18,ALDH4A1,N4BP2L1,NRP2,BTK,SCAPER,CLCN4,RAB26,HOMER3,COL9A2,IFFO1,ABCG1,SUSD5,TBC1D5,EFNA3,EFNB3,ETV1,RRAGB,EZH1,FYB1,TRAF3IP2,DENND2A,GAD1,NCKAP1,LPAR4,GRM1,KLF12,IFI16,INPP5B,ITPKA,KCNJ5,KCNK1,KIFC3,KIT,MX1,NFYA,PDPK1,RGS12,SEC61A2,PBRM1,DZIP1,PKNOX2,KIF13A,DOK5,SOX15,KDM4C,NPAS3,PBLD,TROVE2,TACR1,TIAM1,CDK20,LAT2,ZNF189,HRASLS" Drug 1519_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ASIC1,KIAA1324,MRTFA,CDC42BPA,APBA2,KCNAB2,APBB2,GAS7,ARHGDIG,ALDH4A1,SLC2A11,CADM3,SYNJ2,CACNA2D1,CAMK2B,CBFA2T2,ARHGAP33,CACNA2D2,TPP1,FADS2,BAG4,IPCEF1,CTIF,HSD17B14,RASGRP2,REEP2,HPCAL4,SRCAP,USP19,C1QL1,ADAMTS13,GRM1,GUCY1A1,TJAP1,KCNB1,MAP4,MID1,NEK1,TNPO2,CEP41,GRAMD1C,PRODH,PRPH,CNNM2,RAB3IL1,CEP97,STUM,SLC1A7,PKNOX2,MAPKBP1,TMCC1,DOP1A,KDM4C,ARHGAP26,ZBTB43,ELOVL4,DOCK9,TIAM1,TMOD1,UGT8,ZNF154" Drug 5427_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "DPF1,BIN1,GAS7,APOC1,CDC14B,CDK13,USP2,CBFA2T2,CDH8,CDH18,ADGRG1,SOCS6,CLCN4,SULT4A1,PCYT1B,ARHGEF4,CYBB,MAGI2,ECM2,EDNRA,MBNL2,ERCC2,BAIAP2,FOXG1,GNG3,PCLO,GRM1,NXPH3,KLF12,HLF,KCND3,LIFR,MAP4,GIT1,ADAM22,OPCML,PENK,MBOAT7,PPP2R2B,CEP41,PRKAR1B,PTN,ZCWPW1,FNDC3A,SLC1A7,FAM214B,SLC9A5,WDTC1,ZHX3,HECW1,SPTAN1,CDK19,ARC,SYT5,ZEB1,PCDHGA1,ZNF34,THBS4,TRH,NUP214,DPF3" Drug 5326_UP Ioversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ABHD6,ADRA1D,SEMA6A,EPB41L5,GAS7,PPP4R4,MARK4,CFLAR,ST3GAL5,CFAP410,CAMK2G,NEURL1,CLU,FADS2,NRG2,PDE4DIP,CTH,ARHGEF4,GIT2,SMG7,EFNB3,DMTN,EZH1,OLFM1,FGF12,PDLIM5,GFER,CLASRP,IPO5,MAP4,MEF2C,CD200,MPP2,MSI1,NFYA,NPTX1,PFKFB2,NLE1,CNNM2,SAMD9,NEK11,EMID1,CLIP1,FOXRED2,BCAN,SYBU,PREX2,PEX26,SHANK2,ARHGAP26,IQSEC2,WSCD1,KCTD2,HIRA,FAM155A,NDRG4,SYNC,GDPD5,KCNAB1,SSPN,AP3B2" Drug 2580_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "RALGAPA1,TRMT9B,CDC42BPA,APAF1,APBB2,CDC14B,CDK13,MARK4,NCOA1,KIF1A,BCL7A,CDK5R1,MTMR3,LDLRAD4,CD38,CHN2,TAOK2,RAB33A,HOMER3,AKAP7,FAM149A,BAG4,CREM,SIPA1L1,RUBCN,FCF1,TUBD1,KIAA1109,PDLIM5,CSPG5,GABRA4,GAD2,MSL3,RAB40B,GNG3,DIDO1,ATXN2L,LIG4,SMAD1,MAP4,MEF2C,AFDN,SLC11A2,PIK3R1,CCSER2,SLC25A23,TMEM231,RNASEL,RASA3,SH3BP2,FBXO11,CNKSR2,SLC2A5,SPTAN1,MLC1,ARHGEF9,CRTC1,KCTD2,TPM3,NSD2,PLSCR4" Drug 2281_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "LTBP4,TRMT9B,SEMA7A,ARHGDIG,BRINP2,N4BP2L1,HAP1,BRSK2,TAOK2,CHD5,RIMS2,SPOCK2,CTIF,DCT,SPOCK3,ATN1,ING4,ERCC2,EXTL1,DLC1,CAMSAP1,SCARA3,NEU3,PRUNE2,GPM6A,GPER1,ADAMTS13,GUCY1B1,KLF12,HTR2A,IL11RA,KCNB1,MAP4,MEF2C,NEFM,NNAT,PALM,ENPP2,PDZRN4,CDIP1,PTAFR,PTHLH,SYNDIG1,SEMA6D,ASAP3,CPEB3,SLC1A7,SNAP25,SOX2,ZC4H2,MAPK8IP3,AJAP1,JMJD6,DMXL2,TEX15,CHST8,TLL2,DAAM2,PRMT8,OSBP2,FLRT2" Drug 4102_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "DPF1,NR0B1,TRMT9B,APC,APP,ARHGDIG,RASL11B,N4BP2L1,RGS9,BAIAP3,CAMK2A,CAMK2B,CBLN1,GPR37L1,CHRNA4,NRXN3,STOML1,CSF1R,DBT,DCC,SV2A,SGSM2,DSCAM,DYRK1A,AFF2,TBR1,OGA,DKK3,LYVE1,HPSE2,ICA1,SCIN,KCNN1,AFDN,P2RY13,NEUROD1,NF1,PBX1,PDE2A,ENPP2,PPP1R1A,MARCH1,CCDC40,ARHGEF10L,SCN2B,LRRTM4,MRAS,ASAP3,RPH3A,ARHGAP26,SPTB,MAPK8IP3,ARC,KLHL4,RALYL,AMACR,TRPC3,CADM1,EVI5,KCNAB1,MVB12B" Drug 6019_DN Quinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "KIDINS220,TRMT9B,APBA2,APLP1,FAM131A,NUMB,SLC2A11,ATP6V0A1,MTMR3,CBFA2T2,AP4M1,ARHGAP33,EPS15L1,HOMER3,AKAP7,CREM,ENTPD4,CNTNAP2,GIT2,MFAP3L,CDON,DRD1,TSPAN5,SIDT2,EFNA3,KIAA1109,TRAF3IP2,GLS,MSL3,CNTRL,DIDO1,GRM1,GRM8,ITPKB,KCNJ3,IPO5,MPP2,TAGLN3,NF1,NPR2,MINDY2,GON4L,PTPRE,FAM120C,ATG16L1,RNASEL,NCDN,MAPK8IP3,CEP68,TTBK2,ARC,SATB2,TCF7L2,TRIM2,CRTC1,CHST8,TMOD1,TPM1,VAV1,VIPR2,XRCC4" Drug 6046_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "BIN1,APLP1,CFAP410,CALB1,TAOK2,EPS15L1,TMEM59L,ARHGEF6,AKAP6,CREM,IPCEF1,PHYHIP,KLHL3,EXOG,EIF4G2,MTSS1L,CORO2B,CAMKK2,KHDRBS3,NSG1,FYB1,FYN,C1QL1,GNAO1,PRUNE2,GPR37,GRM7,TJAP1,MAG,MAOB,MAP4,MEF2C,ADAM22,TAGLN3,NOVA2,POU3F4,PPP5C,PKN2,MAPK7,MASP1,RELN,CNTLN,RGS12,SCN2B,MRAS,SLA,FAM214B,SLC12A4,LIMCH1,SNAP25,SNCA,WDTC1,DOK5,IZUMO4,ARHGAP26,SYT11,KIAA1107,PCDHA3,HIF3A,LAT2,SLC13A3" Drug 2550_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "NDRG2,AP2A2,NR0B1,ANK1,ANK3,PKP4,AQP4,ASPH,CACNA1G,HIP1R,RUNX1T1,CDH2,LARGE1,CHRNB2,CTNND2,RIMS2,USP6NL,EDRF1,SNPH,ERBB2,FYB1,ZNF276,GLS,GNAO1,WIF1,PTGDR2,SCRG1,KCNMA1,MAP4,MAPT,SHC3,MN1,MSR1,MYCN,PDE4A,PHKG1,PMP2,PPP5C,PKN2,MAPK8,PTPRN2,KCTD17,SEC61A2,SYNDIG1,SEMA6D,LRRTM4,ZFP2,ZNF821,PKNOX2,SNCA,CAND2,ACSBG1,TAC3,WSCD1,CRTC1,AHCYL2,TGFBR3,FLRT1,LMF1,SLC17A7,SSPN" Drug 4751_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ASIC1,ADORA2A,AMPD3,SEMA7A,APBA2,PPP4R4,CADM3,N4BP2L1,ADGRB3,CACNG1,CDH2,CDH8,ASIC3,MYRIP,NECTIN3,CRMP1,CNTNAP2,RIPOR2,USH1C,EDN1,RCAN2,EXTL1,CACNG3,CACNG2,PTK2B,ZNF589,AFF2,PRELID3A,FYB1,GABRA2,GATM,SRCAP,GRK4,ATXN2L,SYNPO,KCNH1,KCNH2,ADAM22,NTRK2,ENPP2,EPN1,POU3F2,NKAIN1,RFX2,RGS10,RGS12,TCP11L1,EMID1,RYR1,ASAP3,FAM214B,SLN,ZNF415,SOX15,ATP10B,SYT5,VIPR2,SLC13A3,SLC30A3,PRDM2,ITM2C" Drug 3905_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ARID1A,AP2A2,CDC42BPA,EPB41L5,SEMA4G,RGS20,CDK13,NCOA1,ATP2A2,ALDH7A1,BAIAP3,CA12,SCARB1,CDH8,CHM,SULT4A1,CREM,RIMS2,NOS1AP,CTIF,DRD1,DUSP9,MBNL2,PLXNC1,EIF4G2,DLL3,OGA,TMEM8B,DISC1,GCNT2,SRCAP,RAB30,GNAS,GPD2,EML4,KHK,TM6SF1,MMP17,CNOT4,NPPA,NPTX1,PIK3CD,PACSIN1,TNPO2,MAPK8,PTHLH,RGS12,ASAP3,PKNOX2,LIMCH1,SNCA,ZCCHC24,SPTB,CLSTN2,WSCD1,TCF7L2,SLC44A1,DAAM2,TNS1,SYNC,PHTF2" Drug 5075_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "SEMA7A,ARHGDIG,ADGRB2,NRP2,LDLRAD4,CACNA1D,CALB2,RUNX1T1,NEURL1,CHN2,CHRNA4,NRXN3,WHRN,RGS6,CSNK1E,PDE4DIP,MAGI2,RABGAP1L,CDON,DRD1,ATN1,DUSP9,TNK2,MRNIP,MTSS1L,DLC1,FAM49B,SIGLEC8,LYVE1,GPD1,GRIA1,GRIN1,RASSF8,HLF,AFDN,ADAM22,SLCO1C1,NPPA,NRCAM,NUMA1,PALM,RETREG1,GRAMD1C,PROX1,ZSCAN32,RAB3A,PID1,ZMAT4,RGS12,TCP11L1,ST6GAL1,SNCA,ATP10B,MAPK8IP3,DOCK9,THRA,R3HDM1,TRPC3,RPRM,SEMA3B,FAM13C" Drug 6099_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "RALGAPA1,ASIC1,BIN1,ANK2,INA,CDH2,LY86,CNR1,HAPLN1,CHD5,VCAN,CYBB,RASSF2,BRINP1,DBT,JAKMIP2,RABGAP1L,ATN1,SORBS3,TENM1,SRPK3,PTK2B,GAP43,PRUNE2,GPM6A,GPM6B,ATF7,GRK4,PCLO,GRIA1,GRIK5,GRM1,GSTM5,HRH3,IL11RA,KIT,CD200,MYL3,NF1,NTRK2,NTRK3,OMG,SERPINI1,PILRA,PPP5C,CNTLN,PTX3,RPS6KA2,ASIC4,ARHGEF40,SLC11A1,SHANK2,CXXC4,SPTAN1,PHLDB1,VAMP1,TRIM2,TEK,GPR161,TMOD1,CAMK1G" Drug 4976_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ADORA2A,KIDINS220,AP2A2,APC,ST3GAL5,SYNJ2,CAMK2G,FOXN3,SLIT2,TPP1,ABI3BP,RCHY1,SDC3,ARHGEF4,KIAA0586,TOM1,FEM1B,EFNA3,SUGP2,TNK2,MRNIP,DLC1,KAT8,C1orf61,CGREF1,GCNT2,GNG3,PCLO,DIDO1,IGSF1,KCNN2,VWA5A,MID1,MMP16,MSI1,ZNF862,NF1,NPR2,SETD4,PLCD1,MED1,SAMD9,RAD52,ZCWPW1,RGS3,ROM1,SBF1,ZNF821,PPP1R9A,ARHGEF9,SEMA4A,EXOC7,DICER1,TMEM121,CABIN1,FAM155A,UBTF,PLPPR2,PRDM2,EVI5,NUP214" Drug 5002_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ASIC1,KIDINS220,AGT,MRTFA,APBB2,GAS7,BCAS1,RGS20,MARK4,CFLAR,SCAPER,GYG2,CACNA1I,CFAP410,CACNB4,CANX,TAOK2,DNAJB5,CRY2,SIPA1L1,TMCC2,ECM2,HIPK3,HSD17B14,VPS13B,STX2,NRN1,ATP8A1,KAT8,OGA,GABRA2,GAD1,GLYR1,GPR37,NXPH3,MID1,MMP16,OCRL,PACSIN1,PPP5C,PRKAR1B,MAPK7,PTHLH,GTDC1,RPH3A,CCDC88A,TNIK,EMC1,ZC3H13,ATP10B,AJAP1,KAZN,DMXL2,PSD3,TMOD1,PARD3,TRPC1,SLC30A3,SEMA3B,KCNAB1,PHTF2" Drug 7488_UP ST021200; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "KDM5D,LTBP4,APBB2,RGS20,AZGP1,HAP1,FADS2,COL9A3,IFFO1,CHD5,MFAP3L,HP1BP3,RUSC2,DOCK2,DTNB,FEM1B,ING4,FCGRT,GAB1,ZNF44,ATP8A2,ALDH1L1,GNAO1,LPAR4,GPER1,PCLO,FAM107A,PTGDR2,ITIH2,KCNJ5,VWA5A,KITLG,MYT1,NCAM1,NELL2,PDE4D,MAPK8,PTPRD,FAM120C,TCP11L1,KCNIP1,SLC4A3,SLC1A7,FAM214B,CCDC88A,SHANK2,BTBD7,HECW1,SPP1,SPTB,ATP10B,VPS13A,TAC3,TIE1,TK2,CHST5,TRPC1,KCNK12,XRCC4,MVB12B,SSPN" Drug 6036_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "SYN3,ACHE,AGT,C1QTNF1,APOC1,ALDH7A1,BAIAP3,LDLRAD4,P2RX6,ASIC3,SULT4A1,CNR1,SNPH,BRINP1,SPOCK3,CDON,DRD1,EXTL1,F5,FHL1,AGAP2,AFF2,GCNT2,MSL3,GNAO1,LPAR4,STMN2,GRM8,GUCY1A1,HAS2,PTGDR2,HLF,TJAP1,KCNJ5,LAMA2,AFDN,NELL2,PDGFRA,GPR85,PHKG1,SEPT4,POU3F2,PROX1,SAMD9,PTPRB,PTX3,SUGCT,ZFP2,SNCA,IZUMO4,WSCD1,FAM189A1,PCDHA5,SLC35G2,CHST5,TRH,FLRT2,VAV2,MICAL1,ZNF711,KCNAB1" Drug 4498_UP Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ACTN2,AGT,BEGAIN,ATM,CFLAR,BMPR1B,CACNB2,CDH8,EPS15L1,CNTFR,AKAP5,ABCG1,CSF1,RGS6,CNTNAP2,CYBB,GSDME,ECM2,COQ7,DENND4A,NCALD,ZNF549,PIPOX,ARMCX1,FGFR1,SORBS1,GUCY1A2,IRF8,KCNH2,SMAD1,MDM4,MMP16,ADAM22,NEUROD1,NTRK2,ENPP2,PFKFB2,EPN1,CEP41,ELOVL2,PTPRN2,ZSCAN2,RGS4,STUM,DZIP1,SLC1A7,FAM214B,CXXC4,FAIM2,ZHX3,IZUMO4,SPTAN1,THSD1,INKA2,COBL,SEMA4A,KLHL4,TRIM2,VIPR2,SPHK2,KCNAB1" Drug 6723_UP Primidone [125-33-7]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ADCY2,MTUS1,ADGRF5,C1QTNF3,BEGAIN,APC,CDC14B,NOL4,MPDZ,FUBP1,SCAPER,CAMK2B,CDC42,CACNA2D2,SOCS6,TAOK2,NCOR2,PHF14,RIMS2,FAM131B,DAPK3,MFAP3L,ABCC9,ST8SIA3,IGSF6,EFS,CEND1,CAMSAP1,GAB1,MYOZ2,STON1,GRM8,KCNJ5,VWA5A,LSS,MAN2A2,TM6SF1,ADAM22,NELL2,NNAT,NOVA2,RETREG2,SH3TC2,ENOX1,FBXO11,PKNOX2,ARHGEF40,ZSWIM8,BEX1,RGL1,PLCB1,COBL,TAL1,RPGRIP1L,CHST8,TLL2,TRPC3,ZNF24,REEP1,KCNAB1,PARP11" Drug 4606_DN Metyrapone [54-36-4]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "MTUS1,MADD,ADAM15,CAMK2G,B4GALT6,CNOT8,QKI,WHRN,CTNND2,KIAA0513,DBT,RUSC2,SGSM2,ATN1,FEM1B,EIF5,TNK2,MRNIP,EFEMP1,ZNF589,ANKFY1,FYN,DENND2A,TXNL4A,PRRC2B,KIF5C,MITF,NDP,NUMA1,PLCD1,PLEC,RC3H2,PMS2,PPP5C,ZSCAN32,TCP11L1,SAFB,SBF1,ZFP30,AMBRA1,SLC1A7,SMARCA4,WDTC1,TNIK,SS18,EXOC7,IQCE,FBXW11,TCF4,KIAA0930,SZT2,ZNF34,AMACR,TRPM2,UBTF,NSD2,XRCC4,TFIP11,EVI5,HPS4,MVB12B" Drug 3326_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "SYN3,ARID1A,AGT,NME5,KIAA1324,APAF1,GAS7,LDLRAD4,CALB1,USP2,TAOK2,COL9A2,NECTIN3,NCOR2,SPOCK2,USH1C,EDIL3,ELAVL2,ELAVL3,VPS13B,F3,F5,FAM198B,AGAP2,GAD1,ERAP1,ALDH1L1,RUNDC3A,GNAO1,GRM1,KCND3,KCNQ3,MEF2C,KITLG,BCO1,NEK1,PDE3B,PDE4B,LRP12,RFX2,RGS10,ZFHX4,KLHDC8A,GSTCD,SEMA6D,ASAP3,SLC1A2,KANSL3,ARHGEF40,SLC9A5,SNCA,ARHGAP26,SPTB,TBCEL,HEY2,KCTD2,UGT8,WIPF1,SLC13A3,ITM2C,SLC17A6" Drug 4422_UP Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "DPF1,NDRG2,ADRA1D,NR0B1,KIAA1324,SEMA6A,AMPH,CDC14B,RASL11B,BAIAP3,CAMK2B,CCNT1,INA,FADS2,SULT4A1,LY86,WHRN,SNCAIP,VCAN,FAM169A,GREB1,BRINP1,EDNRA,EGR3,GLS,GNG3,ATF7,GPER1,GRM1,KLF12,IL11RA,JAK2,MEF2C,NF1,NPY,OMG,PFKFB4,EPN1,PTHLH,FAT4,ENOX1,RET,RGS4,RGS12,FBXW7,RPS6KA2,SH3GL3,SLN,TROVE2,COLGALT2,THSD1,WSCD1,PCDHGA10,SIK3,HEY1,TNS1,ZMYND8,OSBP2,LAT2,STMN4,ADAMTSL3" Drug 6494_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ARID1A,NDRG2,AP2A2,PPP4R4,ARHGDIG,MARK4,ASPH,N4BP2L1,NRP2,CBFA2T2,TPP1,NCOR2,CSF1R,RIPOR2,ELMO1,RUSC2,DMPK,TRAPPC9,RCAN1,EDN3,NRN1,FABP7,FGFR1,GABRA5,ALDH1L1,SRCAP,GNAL,GPM6B,GPER1,GRB10,GRM8,SOX21,GUCY1A1,HLF,ITGA7,ITIH2,KCNK2,MDFI,MEF2C,MX1,MYCN,OGG1,OMG,PDE1C,SMIM7,PTX3,RFX3,FBXW7,FRMPD1,SLC11A1,HECW1,ATP10B,EPB41L3,ARC,IQCE,PCDHGB6,XRCC4,SLC30A3,ADAMTS9,SEMA3B,JPH3" Drug 6515_DN Trapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "ALCAM,AMH,CDC42BPA,APLP1,FAM131A,BCAS1,PDE8B,DNAH17,MARK4,ALDH4A1,ATM,ALDH7A1,KIF1A,CFLAR,GYG2,CDH8,AATK,FAM169A,SEC14L5,DOCK4,DAPK3,DBT,C2CD2L,DSCAM,SIDT2,SUGP2,PLXNC1,STX2,ERBB2,BAIAP2,GAD1,GPD2,GPR37,GRIK5,ELOVL5,IGSF1,KCNH2,MAP4,ZNF862,NPTX1,NUCB1,RAB3IL1,RAB5B,CEP97,FUZ,NLGN1,SMTN,ZC3H13,NSFL1C,EXOC7,CRTC1,TK2,TMOD1,HIRA,PLPPR2,VGF,ZBTB14,GDPD5,WIPF2,ZNF248,SSPN" Drug 2259_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "DPF1,NLGN4X,AK2,ALCAM,TRMT9B,SEMA7A,APC,AQP6,PRX,ATM,ADGRB3,BMPR1B,GYG2,RHBDL1,SLC16A4,CBFA2T2,CDH2,CHN2,CRMP1,DTNB,EFNB3,MBNL2,VPS13B,STX2,APC2,KIAA1109,FGFR3,DLL3,OGA,ADAM28,GRM8,GSTM5,TJAP1,KCNMA1,KIFC3,PLCB2,CDIP1,LRP12,MINDY2,RELN,SNRK,PTAFR,PTHLH,RFX2,TTLL7,SEMA6D,FRMPD1,ASAP3,DOCK10,ZNF430,SNAP25,ATP10B,ZEB1,PCDHGA1,CRTC1,HEY2,SEZ6L,SLC17A7,MVB12B,NLRP3,SSPN" Drug 5615_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "FZD9,GAS7,ARHGDIG,AZGP1,KALRN,HAP1,HIP1R,EPS15L1,SLC24A2,PICK1,WHRN,CRMP1,HAPLN1,VCAN,CNTNAP2,NOS1AP,SPOCK2,RABGAP1L,EFNB3,PLXNC1,SPEG,REEP2,KIAA1109,TBR1,FYB1,ERAP1,C1QL1,RND1,GLS,PRUNE2,GPM6A,PTGDR2,HTR5A,KCNA2,KCNH2,KCNJ5,KHK,MAG,ADAM22,NF1,OMG,PFKFB2,CDK14,MAPK8,MAPK10,MASP1,SNRK,TRIM68,SEMA6D,ASIC4,ITSN1,CPEB3,SLC11A1,SNCA,ZSWIM8,PHLDB1,ARHGEF12,GPR161,TTPA,UCHL1,DNALI1" Drug 2246_UP Isoniazid [54-85-3]; Up 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "AP2A2,ADGRF5,AMPD3,AMPH,CDC42BPA,SLC4A4,ADAM23,BAIAP3,CALB2,INA,ADGRG1,CBARP,ASIC3,SULT4A1,CRMP1,DCC,DNAH9,EDN3,SEMA3D,MBNL2,ELAVL2,MTSS1L,FOXG1,AGAP2,FYN,ZNF44,SIGLEC8,SRCAP,GFER,CSDC2,GNAL,GNG3,GPM6A,GRM1,IRAK3,KCNMA1,MATN3,MDFI,MYT1,NNAT,TMOD2,LRP12,KLHDC8A,FRMPD1,CPEB3,BCAN,NLGN1,PKNOX2,SLC9A5,CXXC4,NCDN,VAMP1,POPDC3,TAC3,SEZ6L,SLC30A3,NT5M,DNALI1,EPM2A,KAT6A,CAMK1G" Drug 3330_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "AP2A2,NR0B1,C1QTNF1,APOC1,RGS20,RGS11,HAP1,CAMK2B,RUNX1T1,CCK,NEURL1,WHRN,CNTNAP2,RIMS2,SPOCK2,NTM,TRAPPC9,RCAN2,REEP2,FAM198B,AGAP2,AFF2,SORBS1,GAD1,DISC1,RUNDC3A,RND1,TDRKH,IRF8,KCNMA1,KCNQ3,MAOB,ZNF862,NOS1,PCBP3,PLCB2,PLP1,PLTP,LRP12,PLPPR1,KLHL11,WLS,KCNIP1,STUM,ASAP3,ST6GAL1,PKNOX2,SOX3,PEG10,ZNF423,ZC3H13,AJAP1,TAC3,DOCK9,SLC19A3,PSD3,ICAM5,TRPM2,ITM2C,PARP11,DPF3" Drug 3017_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "RALGAPA1,ABHD6,MTUS1,PKP4,PRX,ARHGDIG,ASCL1,RIPK1,RGS11,CACNA1G,MYRF,CACNA2D2,SLC24A2,AKAP6,SNPH,SPOCK3,EXOG,MAMLD1,EGR3,CALCRL,ATP8A1,FER,BAIAP2,GABRA1,GAD1,GAD2,MYOZ2,RAPGEF1,GRIK5,KLF12,HPSE2,IGSF1,SCIN,KHK,LSAMP,MMP16,NTRK2,OPCML,CLDN11,PDE1C,GPR173,EPN1,SLC25A23,MAPK10,PTPN13,ATG16L1,RASGRF1,KCNIP2,SCN8A,LIMS2,SLN,PALLD,TNIK,TRIM2,PHF24,AHCYL2,TPM3,TRPS1,SSBP2,SCG2,ACTR3B" Drug 6779_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-08 3.57E-03 3.30E-06 3.75E-05 61 198 "NDRG2,TRMT9B,KCNAB2,ARHGDIG,RASL11B,CFLAR,CFAP410,CACNB2,CHGA,ZFYVE9,NCOR1,DGKB,ARMCX2,C2CD2L,EFNA3,EFNB3,EGFR,SORBS3,F5,ZIC4,OLFM1,C1orf61,PDLIM5,KHDRBS3,GAP43,CACFD1,IL6R,MAP4,MEIS2,MGAT3,BCO1,PDE1C,SLC25A23,POU6F1,PPARA,MAPK7,PTAFR,PTHLH,ELOVL2,PTN,RIPOR1,ZSCAN2,MRAS,KANSL3,SNCA,KDM4B,ZSWIM8,IQSEC2,PLCB1,TCF7,PSD3,GPR161,TK2,TNS1,FAM155A,UBE3A,FLRT1,VAV2,SYNC,WNK1,EPM2A" Drug CID000005466 AC1Q5UBL Stitch 7.39E-08 3.62E-03 3.34E-06 3.80E-05 49 146 "ABAT,ACHE,ADCY8,ADORA2A,ADRA1B,ADRB2,ALDH7A1,CACNA1B,CACNA2D1,KRIT1,CHN1,CHRM1,SLC32A1,BOC,NR1D2,DRD1,ADGRV1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM8,MEST,MGAT3,OPRL1,PTCH1,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SLC17A7,SLC17A6" Drug CID000065065 N-acetyl-L-aspartate Stitch 7.41E-08 3.63E-03 3.35E-06 3.81E-05 39 105 "FZD9,APLP1,APOC1,ASPA,ATP1A2,CACNA1A,CACNA2D1,CHRNA4,CLU,CNR1,AKAP5,NCAN,CST3,CX3CR1,ACY3,ATN1,GTF2IRD2,FOLH1,GFAP,GRIK1,GRM3,IL12A,LIFR,MAPT,MBP,MOG,MTR,PLP1,SCN3A,IFT122,SPP1,MLC1,SYP,NPL,CLIP2,SLC13A3,ZIC1,GJC2,GAN" Drug CID000006035 bromodeoxyuridine Stitch 7.49E-08 3.67E-03 3.38E-06 3.84E-05 99 376 "ALAD,MAP4K3,AQP4,ASCL1,ATP2A2,BLM,PROM1,CALB1,CALB2,CDH2,TIGD7,QKI,COL11A2,AHCTF1,NTM,DMD,OLIG1,MAMLD1,EGFR,ELAVL3,OLIG2,ENO2,ERBB4,ERCC2,F5,FABP7,FKTN,PPP1R1B,FGF1,ACTL6B,FGFR1,FOXG1,FLT1,AFF2,NELFCD,TBR1,GAB1,CHL1,GAD1,GAD2,GALC,NEU3,MSTN,AHDC1,GFAP,KIRREL3,GJB1,GRIA1,HNRNPK,IGF1,ITGA7,L1CAM,MAP2,MBP,ADAM11,KITLG,PPM1L,MSI1,MYH6,MYO7A,NCAM1,NCAM2,NEUROD1,NODAL,NOS1,NPY,NOVA2,NTRK3,CDK18,PDGFRA,PLCB2,FXYD1,POU3F4,PPP5C,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,GSTCD,RTKN,S100B,SOX2,SPP1,TSPYL2,DDN,SRPK2,SIRT1,TK2,ACTR6,ZFP91,NPDC1,ZIC1,ZIC3,HNRNPA3,SSPN,FXR1" Drug ctd:C029938 nickel sulfate CTD 7.60E-08 3.73E-03 3.42E-06 3.90E-05 330 1610 "SERPINA3,NDRG2,TMCC3,RNF157,ADD3,ADORA2A,ZNF608,INTS2,MTUS1,ALCAM,AMPD3,BIN1,SEMA7A,USP28,CNTNAP1,APBA2,DDO,CACHD1,CDK10,CASK,ARHGAP5,ARRB1,ASGR1,STK33,CAPRIN2,ZBTB10,SLC4A4,ATP1B3,DPY19L3,DOCK11,BACH1,RGS9,NRP2,BID,CFLAR,C1QC,C5,DDR1,CANX,USP2,CD86,ENTPD6,DGKI,REPS2,CDC25B,CDH8,MAGI1,CDO1,ADGRG1,MS4A7,SLIT2,LHX2,ZFYVE9,CLCN4,NMT2,CLTB,IQCK,COL4A5,ABI3BP,CHD1L,ZNF385A,FAM171B,PNKD,CREM,CREB5,CSF3R,FEZ2,IPCEF1,VCAN,PDE4DIP,CTH,RUBCN,MYADM,TOX,DAPK1,SIRPA,ARMCX4,ARMCX2,DCT,LYPD1,RHOBTB1,SACS,CCDC3,ARNT2,CHRDL1,DLX1,DNAH9,SLC29A4,RCAN1,TOM1,MAMLD1,DNAJB6,EDIL3,EDN1,ATL1,CNNM1,RASGRP1,FRY,EFNA3,EBI3,EGFR,AASS,LPAR6,EIF4G1,PLEKHA1,PCOLCE2,ELN,EML1,CALCRL,ENO2,GPHN,RAB9B,EYA1,F3,ARMCX1,ZNF585B,CORO2B,ST3GAL6,CHST15,FECH,FGF1,SEC23B,FOXF2,SEMA4D,FLNC,FLT1,SLC37A3,NOP56,TRIM16,B3GAT1,FYN,ILDR2,GAD1,AHCYL1,GALC,B4GALNT1,IQGAP2,GATM,FAXC,GCNT2,AHDC1,GFRA2,PPARGC1A,KIRREL3,GLRB,GLUL,DCLK2,GNAL,LILRB4,PRUNE2,GPM6B,GPER1,C1QL4,SERP2,NR3C1,GSN,HBA1,HPS5,FRMD5,FRMD3,AGBL5,NEGR1,CPT1C,IRF8,IDH3B,IFI16,SHISAL1,RBPJ,IL12A,INSM1,ITGA7,KCNJ10,KIF5C,KIT,LIFR,NCOA7,MAPT,MATN3,MDFI,MEF2C,MEIS2,MEST,KITLG,MID1,MITF,MMP16,CD200,CCDC80,MX1,NCF2,NFE2L2,ALDH1L2,NOVA1,NPR2,DDR2,NUCB1,OGDH,CLDN11,PBX1,DPY19L2P2,PRTG,PDE3A,PDE4B,PDE4D,SLC10A4,TMOD2,PFKFB3,CDK14,SERPINE2,SNX10,RETREG1,KCTD15,PLEC,PLTP,LRP12,RETREG2,PILRA,CRLS1,PRKAB2,MAPK3,EPDR1,MAPK8,MAPK9,GRAMD1C,SLC22A23,SYTL2,DEF8,ELOVL2,PTPRB,PTPRG,FAM120C,TTC13,ZNF844,TMEM255A,RAP1GDS1,GAL3ST4,TTLL7,ZFHX4,RAVER2,FBXW7,CNTNAP3,RTKN,STX1B,AP1AR,S100B,SEMA6D,SATB1,ATXN1,SFPQ,SGK1,KIF16B,CPEB3,DOCK10,MAGI3,FNDC3A,ANKRD6,FAM81A,BTBD3,SHANK2,ZNF334,NAPB,SNCA,PALLD,PDZD2,TNIK,KDM3A,SPP1,PEG10,ZC3H13,BEX1,MCF2L2,NFASC,ITPRID2,STOX1,SAMSN1,ZC4H2,RGL1,SULF2,GSE1,NSFL1C,JMJD6,VAMP1,TAC3,ATP11A,WWC1,AGTPBP1,TCF4,SATB2,ZEB1,PSD3,ARL10,GZF1,TIAM1,TLR4,TMOD1,BEX4,TNFRSF1B,TNS1,TPD52,NPL,TUBA3FP,TRO,SSBP2,TTPA,ZNF610,PLEKHH2,VAV2,VLDLR,WIPF1,CLIP2,PORCN,RICTOR,ZIC2,PLPP4,LYPD6,ZBTB16,ZNF154,ZNF184,DNALI1,STOX2,SCG2,NAV3,TRIM16L,PLSCR4,FZD3,ADAMTSL3,VANGL2,SNX14,IFT88,GAN" Drug 6916_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.70E-08 3.77E-03 3.46E-06 3.94E-05 58 185 "ABHD6,KIDINS220,ALAD,ARNTL,MARK4,SYNJ1,ST3GAL5,SPAG9,CLGN,PREPL,AKAP12,PDE4DIP,CTH,ARMCX2,DNAJC6,CDKL3,BAIAP2,DPYSL4,NBEA,FYN,CYP46A1,GLS,RAB40B,STON1,KIF3A,KIF5C,NEK1,PCDH9,SERPINI1,PIK3CD,PRPH,PTCH1,PTPN13,SH3BGR,SH3GL3,KIF16B,SYBU,WDR47,SPATA7,ZCCHC24,SPTAN1,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,WDR7,DOCK9,HEY1,ACTR6,BEX4,RUNDC3B,SSBP2,DNAJC12,EVI5,NAV2,SLC17A7" Drug 2330_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.89E-08 3.87E-03 3.55E-06 4.04E-05 55 172 "ADD3,NME5,ALCAM,CDC14B,ARNTL,ST3GAL5,BAIAP3,CLGN,WHRN,SEC14L5,KIAA0513,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNB3,RASGRP2,STX2,ZNF589,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,MITF,NEK1,PCDH9,SERPINE2,SERPINI1,PIK3CD,GRAMD1C,PRPH,SH3GL3,PPM1E,ST6GAL1,PKNOX2,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC30A3,SLC17A7,ITM2C" Drug 3184_DN Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "EP400,APC,ARRB2,MARCH3,CAPRIN2,ATP6V0A1,CFLAR,CFAP410,MAGI1,SOCS6,TAOK2,FAM189A2,ARHGEF6,BAG4,LRIG1,KIAA0586,FBXL5,RABGAP1L,KBTBD11,TOM1,EDNRA,EFNA3,SORBS3,EML1,DMTN,LRRC23,DENND4A,FECH,FGFR1,SEMA4D,CGREF1,GALC,ERAP1,POLL,NR3C1,PADI2,KCNF1,MIA2,NF1,NFYA,NUMA1,PRKAR1B,RAB3A,GTDC1,SLC20A2,THSD1,STX1A,ASTN2,FBXW11,TCF7L2,TRIM2,CABIN1,ZNF384,HIRA,VAV1,VAV2,VIPR2,ZNF45,GDPD5,SSPN" Drug 7493_UP ST021200; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ASPHD1,SYT13,PKP4,CNTNAP1,APBB2,AQP6,CDK10,MARK4,ADAM23,BTRC,CBARP,FOXN3,ZFYVE9,STOML1,RAB26,CYBB,EDIL3,FEM1B,TUBD1,PLEKHO1,LRRC23,BAIAP2,IQCG,SEMA4D,TRMO,CGREF1,RUNDC3A,GRIK5,KLF12,ITIH2,MDFI,CNOT4,ODF2,GPR85,KCTD15,NLE1,CDIP1,RC3H2,PRKCB,CNNM2,PLPPR1,PTPRH,TMEM231,FAT4,KCTD17,OGDHL,WDTC1,TSNAXIP1,ZHX3,COLGALT2,SYP,KAZN,TCF4,TEX15,THRA,TNS1,TRIO,LMF1,MAP3K12,ADAMTSL3" Drug 4575_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ADCY2,PLA2G6,C1QTNF3,TRMT9B,APAF1,PDXK,ARRB2,BACH1,BMP7,FUBP1,CACNA1G,BTRC,SEPT7,REPS2,LARGE1,RAB28,CRY2,CSNK1E,CNTNAP2,ERC2,RABGAP1L,DTNA,REEP2,FGF1,CAMSAP1,GAD2,HBS1L,RUNDC3A,DIPK1A,ITGA7,KCNF1,KCNQ3,SMAD1,MDM4,TAGLN3,MX1,MYT1,NPR2,PALM,CDK18,EPN1,SPATA6,ZSCAN32,CCDC40,RGS10,FOXRED2,SLC1A7,PKNOX2,SLC6A9,ZHX3,IZUMO4,MAPK8IP3,ACSBG1,COBL,TBCEL,OSBP2,LAT2,KCNK12,SLC17A7,PAK5" Drug 3799_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ADORA1,C1QTNF3,LTBP4,TRMT9B,APAF1,CADM3,ADGRB3,RGS9,NRP2,CLDN10,ADGRG1,CHI3L2,CPNE6,ECE2,TOX,DBT,SMG7,DMPK,HS3ST2,SEMA3D,CALCRL,OLFM1,CAMSAP1,PDLIM5,GALC,IQGAP2,GPR162,LYVE1,GJB1,GPR17,STON1,ICA1,KCNN2,ADAM11,KITLG,NCAM2,NPTX1,P2RX7,PALM,PDE4A,C19orf57,POU6F1,RGS3,SH3BP2,CNKSR2,PKNOX2,SLC11A1,KIF21B,ZC3H13,SSTR1,SYT5,SEMA4A,PCDHGB6,CRTC1,DNAH7,ZFPM2,ICAM5,TPM3,CA14,SEMA3B" Drug 2813_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ADORA1,PLA2G6,SEMA6A,MRTFA,APLP1,PPFIA3,PLA2G4C,ATM,ATP2A2,SLC16A4,FOXN3,ASIC3,TAOK2,SLC4A7,RCHY1,ABCG1,ARHGEF10,PHF14,NOS1AP,DNAH9,MBNL2,ENO2,STX2,EZH1,ZNF589,KIAA1109,GAB1,INPP5K,GLS,TDRKH,GSN,ACOT7,VWA5A,MBNL1,KITLG,ADAM22,NDUFA5,NF1,PCDH9,MTRF1L,PKN2,SNRK,WDR25,PTPRO,ARID4A,PPP1R9A,SH3GL3,SLC22A4,SNCA,EMC1,HECW1,FAM168A,SEMA4A,KIAA1107,TBCEL,TRIM2,PCDHGA10,SYNC,EVI5,FIP1L1" Drug 3173_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ASIC1,KCNAB2,CDK13,BTRC,HIP1R,LDB2,SLC16A4,P2RX6,NEURL1,NMT2,HOMER3,PCYT1B,CRMP1,MICAL2,NOS1AP,MYEF2,FRY,C3orf18,LRRC17,NRN1,F5,CORO2B,DLC1,ZMYND10,FHL1,FYB1,CHL1,DISC1,ALDH1L1,ADAM28,GLS,GPM6B,GRM8,GSN,ATXN2L,KCND3,KCNN1,KPNA5,SMAD1,MSR1,DDX25,NPPA,OPRL1,PCDHGC3,PFKFB2,PLCD1,SCN2A,ST6GAL1,BEX1,ATP10B,TROVE2,MLC1,PLCB1,PSD3,R3HDM1,WIPF1,LAT2,PRDM2,NT5M,SLC17A7" Drug 5418_UP Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "NDRG2,LTBP4,ALK,APC,APP,PLA2G4C,ASPH,ST3GAL5,CFAP410,CACNG1,ZFYVE9,FAM189A2,DNAJB5,QKI,SLC4A7,TCEAL2,CPS1,ARHGEF4,DMPK,DTNA,SGK2,DMTN,DENND4A,ETV1,FGFR1,KHDRBS3,PCDH17,RND1,GLS,CNTRL,ATXN2L,ITIH2,ITPKB,KCNJ5,KCNK1,LIG4,BCO1,NOS1,PDE3B,PIK3CD,LRP12,PRKAR1B,MAPK8,PTN,ZFHX4,TCP11L1,ZNF821,STUM,PEX26,SMTN,PKNOX2,RIMS1,PDZD2,EMC1,PLCB1,TBCEL,ZNF34,SYNC,NT5M,TIGD6" Drug 5055_UP Norethindrone [68-22-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "NDRG2,APBB2,APOC1,AQP4,PRX,PPP4R4,PDE8B,BMPR1B,CACNA1I,CAPN3,LDB2,SCARB1,CACNA2D2,CLCN4,IFFO1,CREM,RIMS3,CNIH3,ATN1,DTNB,SEMA3D,EIF4G2,VPS13B,MTSS1L,REEP2,OLFM1,FAM49B,SIGLEC8,GPR17,GRM7,GPR45,KLF12,SHISAL1,KCNJ3,MOBP,MX1,CNOT4,NTRK2,PDE4B,PPARA,MINDY2,LRRN3,PROX1,ELOVL2,ZSCAN32,PID1,RGS10,IL17RB,KIF13A,KDM4B,ZC3H13,PHLDB1,TBCEL,DNAH7,TLR4,RUNDC3B,ZNF74,REEP1,ZNF225,KCNAB1" Drug 3989_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ADD2,ALK,PPP4R4,ARHGDIG,CCDC181,NRP2,SYNJ1,CALB2,ARHGAP33,PLEKHB1,TPP1,CNTFR,IFFO1,TCEAL2,ABCG1,LRIG1,CSNK1E,SUSD5,ARHGEF4,NTM,RABGAP1L,TRAPPC9,ABCC9,SNX29,EDNRA,EFNB3,CELSR3,SORBS3,NRN1,DLC1,FAM49B,GNAO1,GRM7,KCNN3,KIFC3,SLCO1C1,NPY,ENPP2,ST8SIA5,PLCD1,DCHS2,CNNM2,BEND5,RGS12,RNASE1,MYH14,ROM1,MRAS,DOCK10,ZHX3,PHLDB1,ACSBG1,OBSL1,SPX,TUBB1,VAV2,VIPR2,NDRG4,WNK1,VPS35L" Drug 5952_DN radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.97E-08 3.91E-03 3.55E-06 4.04E-05 60 194 "ADRA1B,KIDINS220,BEGAIN,PPP4R4,NCOA1,DDX3Y,NRP2,PROM1,FOXN3,CHGA,SOCS6,LHX2,RAB33A,SH2B1,HAPLN1,NCOR2,AATK,TBC1D5,SPOCK2,G3BP2,RABGAP1L,ATN1,EFNB3,EGFR,EIF4G2,NRN1,CAMSAP1,PRELID3A,C1QL1,GNG4,GPM6B,GPR19,HSD17B1,KCNN1,KIFC3,MEF2C,AFF1,MMP17,ZNF862,P2RY13,SLCO1C1,NFYA,OPRL1,PDE4B,GPR85,PFKFB2,SEMA6D,DZIP1,ARHGEF40,OGDHL,KDM4B,WDTC1,ZC3H13,COBL,PCDHGA10,CRTC1,GPR161,TNS1,OSBP2,VAV2" Drug CID000439587 polyproline Stitch 8.12E-08 3.98E-03 3.61E-06 4.11E-05 82 295 "MTUS1,BIN1,ANXA7,APBB1,APBB2,LRRC4C,APP,ATP1B3,RIPK1,ADAM15,RGS9,CD86,CDC42,CFL2,NGEF,CNR1,WHRN,AKAP5,TRIM69,ARHGEF4,CTNND2,USP6NL,SIRPA,ELMO1,RUSC2,DYNC1I1,ABI1,EGFR,SORBS3,TENM1,TNK2,ELN,EPS8,PPP1R1B,ACTL6B,EVL,PDLIM5,FYN,AHDC1,TXNL4A,TCERG1,RAPGEF1,PTPN5,PACSIN2,HNRNPK,RBPJ,MATK,MYO5A,NCF2,NPY,TREM2,PCSK2,PENK,PLEC,PACSIN1,SH3KBP1,RASGRF2,YY1AP1,SNX22,PTGR2,S100B,FOXRED1,SCG5,SH3BP2,SH3GL2,SH3GL3,SLA,SHANK2,SLC20A2,SNCB,PALLD,SOX5,FNBP1,ACTR6,TMOD1,TP53BP2,WBP2,MICAL1,WIPF1,PLPPR5,SLC17A7,JPH3" Drug CID006419759 K00077 Stitch 8.16E-08 4.00E-03 3.63E-06 4.13E-05 66 221 "SLC12A5,ADORA2A,ADRA1B,DDR1,CALM1,KRIT1,LRBA,CDC25B,CNTFR,AKAP5,NRG2,CRY2,EGFR,ELAVL3,EIF1,ERBB4,PTK2B,PPP1R1B,FGF1,SEMA4D,GFRA1,GFRA2,STMN2,GRIA1,GRIA4,MYLK2,NIM1K,IL6ST,KCNJ3,KCNJ5,LIFR,MBP,MEF2C,HCN1,NTRK2,NTRK3,PDPK1,PIK3C2A,PIK3CD,PIK3R1,PLXNB1,PTPA,PRKACB,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,RET,RTKN,CDK5RAP2,NFASC,TAL1,ZFP91,TNFRSF1B,TPM1,TPM2,TPM3,TPM4,VGF,STMN4" Drug CID000415676 NSC71948 Stitch 8.17E-08 4.00E-03 3.63E-06 4.13E-05 47 138 "ACHE,APAF1,APLP1,APP,CA4,CACNA1A,CACNA1B,CLU,CNR1,HDAC9,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GAP43,MSTN,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSP90AA1,IGF1,MAPT,NEFM,NEFH,OGG1,OPA1,PAH,PENK,ABCB1,PACSIN1,PTX3,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SNCB,SNCA,SST,UBC,PRTFDC1,JPH3" Drug CID000003689 ifenprodil Stitch 8.45E-08 4.14E-03 3.75E-06 4.27E-05 30 71 "ADORA1,ADRA1B,AQP4,DMTN,ADGRV1,FYN,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KCNJ5,KITLG,OPRL1,PDYN,RASGRF1,RASGRF2,UBC" Drug CID000000738 glutamin Stitch 8.68E-08 4.26E-03 3.83E-06 4.36E-05 116 461 "ABAT,ARID1A,APAF1,NCOA1,CFLAR,CACNA1A,CACNA2D1,CALB1,HAP1,RUNX1T1,CBS,KYAT1,CD38,DNAJB5,QKI,CPS1,CREM,NCOR1,NCOR2,CSNK1E,HDAC9,EARS2,MAML1,DCTN1,MYEF2,SNAP91,DLG3,DLG4,ATN1,MAMLD1,DNAJB6,OPTN,EN2,ENO2,HSPA12B,KAT8,PPP1R1B,BAIAP2,AGAP3,FOXO3,AFF2,ST6GALNAC3,GAA,GART,CPLX2,GGT7,GGT5,PPARGC1A,LYVE1,TXNL4A,TCERG1,GLS,GLUL,LNX1,GPR37,GRIK1,NR3C1,GRM1,CIT,KAT7,CELF3,ATXN2L,HSP90AA1,KCNA1,KCNN1,KCNN2,KCNN3,LIG4,PACRG,MAPT,MBNL1,PDE1B,PENK,POLG,POU3F2,PPP2R2B,PRKCG,MAPK3,MAPK8,MAPK9,PRODH,PRPSAP2,PSMA6,PSMD13,RAB3A,RDX,SLC6A15,SEC61A2,ATXN1,ATXN7,SCN4B,SFPQ,ASRGL1,HSPA4L,SH3GL3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SIRT2,SNCA,NMNAT2,ZNF423,BEX1,SYT1,TF,SIRT1,KAT6B,TNR,ZNF384,UBC,UCHL1,SLC38A1,SLC17A7,KAT6A,JPH3" Drug 1971_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 8.70E-08 4.27E-03 3.83E-06 4.36E-05 59 190 "ADD3,APBB2,ARNTL,MARK4,BACH1,WASF1,CAST,HIP1R,LRBA,UBE2L6,PREPL,FEZ1,CX3CR1,RABGAP1L,DPYSL2,EFNA3,FAM13A,ABI2,LPAR6,EXTL2,TESK2,FECH,PDLIM5,FYN,ARFIP1,GLS,IFI16,ITGA7,KIF5C,MEF2C,NEK1,NRGN,NTRK3,SERPINI1,GPSM2,PKN2,PTK2,SPDL1,C1orf54,RAP1GAP,BSDC1,SGK1,ITSN1,CCDC88A,ZCCHC24,SPTAN1,KIF1B,TSPYL2,THSD1,ZC4H2,CEP68,RGL1,STXBP1,ZEB1,AHCYL2,DNAJC12,PLPPR2,ATP6V0E2,ITM2C" Drug 337_DN felodipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ASIC1,KDM5D,BRAP,CDK13,ASCL1,CADM3,FGF17,MTMR2,CACNA1I,RUNX1T1,CHRNB2,NIPBL,AATK,ARHGEF10,OSBPL3,PDE4DIP,GREB1,RIMS3,DCT,FEM1B,VPS13B,RCAN2,EFS,ZMYND10,FGFR1,FOLR2,KHDRBS3,ZNF44,NEU3,ZNF276,HPGDS,NR3C1,NXPH3,ARHGAP19,KCNQ3,MATK,MBD1,MN1,MYO6,MYO7A,NNAT,PLXNB1,TMEM231,C1orf54,LGR4,SATB1,ITSN1,FERMT1,KBTBD4,THSD1,ZC4H2,WASHC4,PCDHA5,CHST8,CDH22,SEZ6L,TUBB1,AMOT,LMF1,SLC13A3,MPPE1" Drug 2822_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ACTN2,SLC12A5,APBA2,KCNAB2,PPFIA3,PDE8B,ASPH,RASL11B,ATM,STX16,SLC2A11,KRIT1,RCBTB2,B4GALT6,RAB28,RCHY1,NCOR2,USP6NL,NOS1AP,RASSF2,SGSM2,DTNA,HSD17B14,DMTN,ZNF589,OGA,ERAP1,GCNT2,RND1,TDRKH,GRM8,VWA5A,ADAM22,NF1,TREM2,CDK18,PDE3B,CCSER2,PLCD1,LRP12,PPP3CC,RPS20,AP1AR,SFPQ,RASA3,SLC1A3,EPN2,EMC1,NPAS3,THSD1,FAM168A,SEMA4A,SZT2,PCDHGA10,CABIN1,ZMYND8,HIRA,PLPPR2,VLDLR,EMSY,HPS4" Drug 5384_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "SYN3,ADRB2,CDC14B,CDK13,PDE8B,BCL2L2,CFLAR,CDK5R1,CACNA1D,CAMK2G,CBFA2T2,AKAP5,NRG2,NCOR2,IPCEF1,SDC3,SPOCK2,NTM,CDON,DRD1,SGK2,EN2,COQ7,RRAGB,FHL1,HPCAL4,SORBS1,PRELID3A,KHDRBS3,SRCAP,USP19,GLS,POLL,GNG3,CNTRL,KLF12,HLF,VSIG4,DHX35,KCNK2,MAP2,MID1,AFDN,CD200,NF1,NOS1,PAH,CDK18,PDE3B,LRP12,LRRN3,PTPRH,TRIM68,FBXO11,PKNOX2,ATP10B,WSCD1,ZEB1,TMOD1,SLC30A3,JPH3" Drug 4159_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ADRA1B,AP2A2,CDC14B,ARHGDIG,CDK13,ADGRB3,KALRN,CAMK2B,CBARP,CHN2,CHRNB2,TAOK2,FADS2,FAM149A,ARHGEF10,MICAL2,VCAN,SV2A,DRD1,ATN1,ST8SIA3,C3orf18,MTSS1L,CORO2B,FAM49B,FYN,SIGLEC8,GATM,RUNDC3A,POLL,GRK4,GRM1,GRM8,GUCY1A2,HAS2,IFI16,IL6R,KCNC1,KCNJ5,KCNN1,MID1,MOBP,PCDH8,GPR85,SPATA6,POU3F4,SAMD9,SNRK,TTLL7,FRMPD1,CNKSR2,SLC11A1,BTBD7,SMARCD3,AJAP1,ADGRL3,SYNE1,THBS4,VAV2,ZNF711,WNK1" Drug 3841_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "SYT13,PLA2G4C,MYRF,LDLRAD4,CACNA1A,CDO1,CHRNB2,CLTB,FADS2,CNR1,CNTN1,PLCH2,RASSF2,CTIF,RUSC2,DRP2,ATN1,DYRK1A,EDN1,EFNB3,AASS,ING4,OLIG2,MTSS1L,PTK2B,DLC1,OLFM1,CAMSAP1,DISC1,GPM6A,GPER1,GSTM5,IRF8,KCNJ5,KHK,LSS,MEF2C,MMP17,MOBP,MSR1,KCNK10,PDZRN4,SPATA6,POU6F1,PRKAR1B,ZFHX4,SELL,ASAP3,KIF13A,KDM4B,ZNF423,SPTB,JMJD6,TBCEL,DOCK9,CRTC1,THRA,DAAM2,FLRT2,SLC30A3,ITM2C" Drug 2994_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ABAT,ABHD6,FZD9,AMPD3,ATP2B3,ALDH7A1,MYOM1,BMP7,CACNA2D1,HIP1R,CDH10,AKAP6,NRG2,NCOR2,CNTNAP2,PITPNM3,NTM,EXOG,TRAPPC9,ST8SIA3,EDN3,CNNM1,EFNB3,SRPK3,STX2,CACNG2,FGFR1,DCTN2,FYB1,GAB1,GABRA5,GPR75,PTGDR2,SCIN,PACRG,MYH3,NELL2,EPN1,BCAS3,LRRC49,PTHLH,RASGRF1,GAL3ST4,RFX2,SH3BGR,ASAP3,CNKSR2,SLC1A7,SLC11A1,PALLD,SOX2,LHPP,ROBO3,PHF24,PCDHA5,ATP13A2,TIAM1,UGT8,PMEPA1,PRDM10,FZD3" Drug 3626_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "MRTFA,AMT,APAF1,N4BP2L1,AZGP1,RGS11,MYRF,LDLRAD4,CACNA1D,CAMK2B,DLGAP2,TCEAL2,CSF1,VCAN,CTIF,DNAJC6,ZNF804A,FAM13A,PLXNC1,TENM1,ERCC2,PIPOX,CAMSAP1,GABRA5,NEU3,GNAL,GRB10,NR3C1,GRM7,HTR2A,INPP5B,ITIH2,KCNH2,LAMA2,MAG,MDFI,TAGLN3,MYT1,NELL2,OPCML,PCDH9,TMOD2,CAMKV,POU3F4,PPARA,CEP41,MASP1,PLPPR1,RAD52,C1orf54,RGS4,EMID1,ZFP2,PDZD2,ACSBG1,POPDC3,IQCE,PCDHGA1,DOCK9,ICAM5,CHST5" Drug 7202_UP Glibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ADD1,KIDINS220,ALK,APOC1,SPTBN4,PLA2G4C,MARK4,CCDC181,ATP2B2,CADM3,KSR1,LDLRAD4,KALRN,CBFA2T2,ARHGEF2,ARHGAP33,STOML1,DNAJB5,LY86,CNTFR,NCOR2,ARHGEF10,CNTNAP2,NOS1AP,TM9SF4,SPOCK3,HS3ST2,RCAN1,DTNA,EDNRA,PLXNC1,EN2,KIAA1109,FGFR3,ANKFY1,FYB1,GABRA1,ITPKB,KCNH2,MAP4,MSI1,SERPINE2,PRKAR1B,MAPK7,MAPK8,RAD52,SLC1A7,SNCA,KDM4C,PHLDB1,TRIM2,PSD3,CHST8,SPX,ZNF34,THRA,AMACR,SYNC,DNALI1,RNF170,SSPN" Drug 2737_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "BBOX1,CDC42BPA,ANK3,ATP1A3,KSR1,KALRN,CDH2,DLGAP1,CHRNA4,ABCG2,DNAJB5,COL9A3,NCOR2,PDE4DIP,ARHGEF4,RIMS2,PHYHIP,BRINP1,SRGAP3,DYRK1A,ST8SIA3,MBNL2,AASS,EPB41,MTSS1L,FHL1,GABRA3,ZNF44,SEPT9,GRK4,GRIN1,GRM8,SOX21,GUCY1A1,HTR5A,KCNC1,KCND3,MGAT3,MMP16,PTPRB,KHDRBS2,RGR,SCN2B,FRMPD1,NLGN1,KANSL3,SLC6A9,SNCA,PALLD,SOX2,ACSBG1,SYT5,TIAM1,RIMBP2,SEZ6L,TRIO,TRO,LMF1,STMN4,FAM13C,TIGD6" Drug 6612_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ACHE,ACTN2,C1QTNF1,LTBP4,EPB41L5,APOC1,ASTN1,BMPR1B,SYNJ1,CACNA2D1,HAP1,SYNGR3,DCLK1,CHRNB2,SLC22A6,RAB33A,CP,CREM,ABCG1,LRIG1,DGKG,DBT,C2CD2L,SMG7,DTNA,EFNA3,IRAK4,SPEG,ZNF589,CPLX2,ZNF276,GRIK5,PADI2,ATXN2L,ITPKA,KCNH2,KIFC3,LMO2,MMP17,NPR2,PALM,PPARA,CEP41,ELOVL2,PTN,PTPRN2,ZSCAN2,MARCH1,ROM1,FBXW7,SYNDIG1,IL17RB,SH3BP2,ASAP3,WDR37,SLC1A7,TMCC1,PHLDB1,ZMYND8,FLRT2,DPF3" Drug 4311_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "DPF1,ADORA3,LTBP4,ANK2,GAS7,ALDH4A1,BMP7,BMPR1B,SYNJ2,LDLRAD4,RUNX1T1,ADGRG1,LHX2,DNAJB5,AKAP5,IFFO1,NCOR2,DMPK,ATN1,SORBS3,TENM1,ELAVL3,ELN,OLFM1,FGF12,FGFR3,FOXF2,AFF2,DCTN2,SEPT9,GPR162,CSDC2,RAB30,PRUNE2,GRM7,ITGA7,NPTX1,NPTX2,NRCAM,PCDH9,CDK18,PFKFB4,SPATA6,TNPO2,PPP2R2B,LRRN3,PRKAR1B,RET,PNMA8A,SCN2B,SLC1A7,HECW1,KLHL4,MICAL1,SLC13A3,XRCC4,ZIC3,ZNF24,LAMP5,HRASLS,NUP214" Drug 3892_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "C1QTNF1,ALCAM,GAS7,CDC14B,DNAH17,CHRD,SLC4A4,ATP2B2,N4BP2L1,GYG2,BSN,CAMK2B,SLC16A4,FOXN3,TPP1,ARHGEF6,TCEAL2,DNAJC6,DTNB,EDIL3,ELAVL3,KCNMB2,F5,B3GAT1,GAB1,GABRA2,SIGLEC8,MSL3,GRIK5,GRIN2C,GUCY1B1,NXPH3,IRF8,TJAP1,KCNJ5,KCNN1,AFDN,FXYD7,NNAT,OPRL1,GDPD2,SNRK,CRTAC1,RGS4,ROM1,EMID1,KCNIP1,HKDC1,PREX2,SLC11A1,NFASC,CLSTN2,MAPK8IP3,DOCK9,CRTC1,ICAM5,PRMT8,VIPR2,ZFP37,STMN4,KCNAB1" Drug 3898_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "NDRG3,KIAA1324,SPARCL1,ALCAM,LTBP4,BEGAIN,CDC14B,RGS20,SLC4A4,NRP2,SCAPER,CFAP410,USP2,RCBTB2,CHM,NMT2,CLTB,CRMP1,DCAF4,MFAP3L,RUSC2,SRGAP3,RABGAP1L,EDNRA,RASGRP2,IGSF6,REEP2,FGFR1,CAMSAP1,PDLIM5,STON1,TJAP1,JAK2,KIT,LMO1,MEF2C,MIA2,PCBP3,PLP1,CEP41,ZSCAN32,NUDT11,CARF,RPS6KA2,KCNIP1,OGDHL,PEG10,CDK19,THSD1,INKA2,MAPK8IP3,ROBO3,SYNE1,DOCK9,HEY2,TMOD1,TRO,UCHL1,FLRT2,LAT2,SLC30A3" Drug 2834_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "NDRG2,SLC12A5,AP2A2,SEMA6A,ALCAM,MRTFA,APBB2,APC,CDC14B,MARK4,SLC2A11,SYNJ1,CBFA2T2,ARHGEF2,SOCS6,LHX2,RAB28,ZFYVE9,PLAA,CLU,NRG2,CRMP1,CSF1,PDE4DIP,RIMS3,DAPK3,SPOCK2,RABGAP1L,DTNA,ING4,ZNF589,FGFR1,EFCAB2,OGA,GAD2,TDRKH,GRM1,ELOVL5,MAOB,MAP4,MEIS2,MITF,ADAM22,ZNF862,PENK,PLTP,PRKAR1B,RELN,PTHLH,PTN,RAB3IL1,RAD52,RAVER2,ASAP3,SNCA,KDM4C,UNC5B,ATP10B,TROVE2,TCF7L2,VAV2" Drug 7146_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ASIC1,ADRA1D,MRTFA,AMPD3,CDC42BPA,SHROOM2,RGS11,IQCK,RCHY1,CREB5,EDRF1,SMG7,EXOG,EMX2,ETV1,F3,TESK2,SCARA3,FYB1,TMEM8B,LYVE1,GPM6B,CNTRL,SYNPO,SCIN,INPP5B,KCNC1,MAPT,NUMA1,PDE4B,PDE4D,PDGFRA,PMP2,FA2H,PPP5C,MAPK7,RAB5B,RALGDS,RGS10,PAQR6,FUZ,AMBRA1,EPN2,SLC9A5,SHANK2,SLC22A4,IFT122,RBM34,WDTC1,DDN,PHLDB1,ATP11A,KAZN,CHST8,TIAM1,TK2,BHLHB9,CABIN1,LAMP5,KCNAB1,TIGD6" Drug 6668_UP Bemegride [64-65-3]; Up 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "AK2,SYT13,CDK13,ATP6V0A1,AZGP1,ADGRB2,RGS11,CFLAR,MYRF,BAIAP3,CACNA2D1,CACNG1,HAP1,HIP1R,RUNX1T1,CACNA2D2,TAOK2,DNAJB5,HOMER3,SH2B1,PDE4DIP,TOX,MYEF2,RABGAP1L,ARNT2,DTNA,DUSP9,EDN1,ETV1,FAM198B,OLFM1,SIGLEC8,GNAO1,AP4S1,KLF12,ITGA7,ITIH2,KCNJ5,KCNQ3,MAP2,ADAM22,MYT1,PENK,RETREG1,PLP1,MED1,LRRN3,PRPH,PSD,RGS7,RASA3,SLC11A1,SNCA,PHLDB1,ACSBG1,MLC1,ASTN2,SZT2,PHF24,R3HDM1,STMN4" Drug 2309_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ALK,CDC42BPA,CDK13,RASL11B,SLC4A4,CFLAR,MTMR3,CACNA1D,RUNX1T1,INA,CBFA2T2,KCNAB3,ARHGAP33,CHRNA4,TAOK2,EPS15L1,SNCAIP,CNTNAP2,ECE2,RASSF2,DUSP9,HIPK3,VPS13B,ERCC2,SPEG,F5,FGR,CSPG5,GABRA5,ERAP1,DISC1,ATP8A2,SRCAP,GFER,GLYR1,ITIH2,LSS,CD200,ADAM22,MSR1,ENPP2,PLCD1,PLTP,PACSIN1,POU3F4,SAMD9,ACSM5,CCDC40,RYR1,STUM,CNKSR2,LIMCH1,SNCA,SP4,ATP10B,TMOD1,DAAM2,OSBP2,DNALI1,AP3B2,JPH3" Drug 3198_UP Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "BEGAIN,BIN1,KCNAB2,GAS7,PLA2G4C,ATP1A3,AZGP1,CFLAR,BTRC,CACNA1D,RUNX1T1,SLIT2,ZFYVE9,NRG2,CREM,IPCEF1,CNTNAP2,PHF14,NOS1AP,SRGAP3,ATN1,EDN1,PLXNC1,ING4,ZNF549,EYA1,ABCA8,CORO2B,ST3GAL6,HBS1L,CSDC2,GPR12,GRM3,GUCY1A2,HLF,INPP5B,AFDN,MSR1,MYCN,ZNF862,NEUROD1,NOVA2,GPR85,PPP1R1A,MAPK7,FAM184A,RGS12,MYH14,SH3BP2,EPN2,SHANK2,SNAP25,PEG10,SPTAN1,CDK19,SYT11,TCF4,TNS1,TRIO,TUBB1,NT5M" Drug 2319_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "C1QTNF3,AMPD3,CDC42BPA,APBB2,PPFIA3,BMP7,SYNJ2,CAMK2G,KYAT1,SLIT2,QKI,FEZ1,CSNK1E,PPP6R2,KBTBD11,SORBS3,DMTN,LRRC23,DENND4A,F3,ACSL4,KIAA1109,BAIAP2,GPR153,RNFT2,ELOVL5,ITPKB,KCNN2,TM6SF1,GIT1,ZNF862,NCAM2,NRGN,PALM,CDK18,PPP2R2B,TMEM104,WDR25,ELOVL2,TMEM231,TRIM68,ROBO1,TCP11L1,SBF1,ZNF821,ANKRD6,CLSTN1,BTBD7,KIF13A,KDM4B,ZCCHC24,ZBTB43,POGZ,PLCB1,TACC1,ZKSCAN5,MICAL1,WIPF1,HPS4,NAV2,KAT6A" Drug 2760_DN Riboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "AP2A2,APBB2,APOC1,PPFIA3,APP,MARCH3,ASPH,BMP7,CA12,KYAT1,CNOT8,ZFYVE9,PDE4DIP,TBC1D5,KIAA0586,MFAP3L,DTNA,MBNL2,MRNIP,EML1,VPS13B,KIAA1109,FGFR1,B4GALNT1,GNG4,CACFD1,NR3C1,INPP5B,KCNH2,KPNA5,MAPT,MPP2,NEK1,ODF2,PC,MBOAT7,CEP97,RAD52,GTDC1,RNASEL,ROM1,SLC22A4,SMARCD3,WDTC1,SOX3,UNC5B,NXT2,STX1A,PLCB1,ASTN2,PCDHA6,ZNF34,TMOD1,CADM1,NSD2,CLDND1,KCNK12,SF1,FTSJ1,PHTF2,SENP7" Drug 4062_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "BEGAIN,CDK13,BRINP2,ATP2B2,BCHE,RGS9,BMP7,TMEM257,CBARP,NRXN3,STOML1,AKAP6,RCHY1,NRG2,NCOR2,CSF1R,CHD5,CNTNAP2,PHYHIP,C2CD2L,AK5,DMD,EDIL3,EDNRA,ZNF391,PTK2B,DLC1,AGAP2,GAD2,DISC1,ATP8A2,CYP46A1,PCDH17,POLL,ATF7,RAPGEF4,ADAMTS8,IRAK3,PTGDR2,ELOVL5,HSD17B1,IGF1,KCNF1,AFDN,NINJ2,PAK3,PDE4D,PFKFB2,RAB3IL1,RGS4,SEMA6D,SCN2B,ASIC4,PKNOX2,SS18,ZFR2,KLHL4,DICER1,CADM1,KCNK12,KCNAB1" Drug 6699_UP Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "GRAMD1B,ADORA3,PLA2G6,AMH,APAF1,APBB2,APC,ARRB2,PTCH2,ATM,BMP7,LDLRAD4,BTRC,KALRN,RUNX1T1,CHN2,HOMER3,COL9A2,AKAP5,ENTPD4,VCAN,PHF14,DAPK1,C2CD2L,LYPD1,SRGAP3,HIPK3,MBNL2,KCNMB2,ETV1,FAM198B,ATP8A1,ERAP1,SIGLEC8,GPER1,ATXN2L,IL12A,LAMA2,MAN2A2,MIA2,LYRM9,NF1,CNOT4,NOVA2,SPATA6,RAD52,RGS12,RPS6KA2,ZFP30,CPEB3,DZIP1,SLA,FAM214B,ACSBG1,PSD3,DICER1,THRA,TIMP4,UGT8,ZNF24,SENP7" Drug 2506_UP Estropipate [7280-37-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "C3orf14,ADCY2,ADORA1,ANK3,LGR5,AQP4,ATP1A3,SGCE,CACNG1,USP2,NRXN2,CNTFR,CABP1,RIMS2,RIMS3,BRINP1,HS3ST2,DRD1,ST8SIA3,ELN,COQ7,DMTN,ERBB4,HPCAL4,GAB1,SIGLEC8,TOX3,GNAO1,GRIA4,GRIN1,ADAMTS8,GRIN2C,RASSF8,KCND3,MAG,MMP16,MYO6,NEUROD1,NRCAM,PHKG1,PRKAR1B,NUDT11,KCNIP2,SCN2B,SEC14L1,ASAP3,CNKSR2,ABLIM3,PEX26,SLC6A9,SLN,SOX10,DOK5,ASTN2,KIAA1107,TCF7L2,AHCYL2,DNAH7,TIAM1,TK2,SENP7" Drug 7391_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ASPHD1,ASIC1,ADCY6,NME5,APC,GAS7,CDC14B,DNAH17,MARK4,ATP1A3,SLC4A4,CDK5R1,BTRC,NCOR2,CSF1R,CTNND2,USP6NL,TBC1D5,CNIH3,DPH1,ATN1,EDNRB,ELN,DENND4A,ETV1,FGF1,FYB1,GFER,ZNF276,GPR75,GRM1,RNFT2,DHX35,TJAP1,ITPKA,RETREG1,POLG,LRRN3,PROX1,CNNM2,TMEM104,WDR25,CCDC40,RAD52,FBXW7,SLC1A7,PPP4R3A,SLC6A9,SNCA,SOX2,TSNAXIP1,SPTAN1,VAMP1,ARHGEF9,GPR161,R3HDM1,CABIN1,VIPR2,REEP1,EVI5,NUP214" Drug 4539_UP Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "MTUS1,FAM135A,APBB1,GAS7,CDK13,ASCL1,BRINP2,NCOA1,SLC4A4,RGS11,NRP2,CACNA1D,SLC16A4,SEPT7,ASIC3,VAX2,LY86,CSF1,IPCEF1,CHD5,EDRF1,DTNB,RGS17,ETV1,KIAA1109,FGF1,FGFR1,FOXG1,DPYSL4,NSG1,FYB1,SRCAP,GPM6B,GRIK5,GRM7,PTGDR2,ATXN2L,KCND3,KIF5C,MAPT,P2RY13,NF1,NOVA2,PDE4D,PURG,MAPK10,PROX1,PTPRB,KHDRBS2,PNMA8A,TMEM206,TCP11L1,SLC2A5,SPTB,SYT5,ZEB1,TMOD1,SSBP2,VGF,STMN4,KCNAB1" Drug 6458_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ABHD6,SEMA6A,APBB2,APP,CDC14B,PLA2G4C,MARK4,ATM,BCL2L2,ST3GAL5,CACNA1I,BTRC,CACNA1A,SEPT7,CNTNAP2,GREB1,HP1BP3,TMCC2,DTNA,EFNA3,RBM12,SORBS3,EPB41L2,SCML2,FHL1,MSL3,NUDT21,HSD17B1,INPP5B,VWA5A,NELL2,NF1,SLC11A2,P2RY1,PC,PIK3CD,PPP5C,ELOVL2,RIPOR1,MYH14,ATXN2,BCAN,ABLIM3,SLC1A7,SMTN,SIRT2,WDTC1,DOK5,EMC1,ARC,TBL1X,AHCYL2,TMOD1,RBFOX2,VAV1,MICAL1,SYNC,MAP3K12,HPS4,SEMA3B,PCBP4" Drug 3169_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "KDM5D,BEGAIN,AMT,APAF1,KCNAB2,ARHGDIG,DDX3Y,ALDH4A1,ATP1A3,GYG2,CACNA1D,CAMK2B,HIP1R,ARHGAP33,FOXN3,CHN2,B4GALT6,TPP1,STOML1,TMEM59L,CPS1,OSBPL3,DOCK4,TMCC2,ATN1,DTNA,EFNB3,PLXNC1,TNK2,ERBB4,OLFM1,FYN,SEPT9,RND1,TDRKH,ICA1,JAK2,NOVA2,NPPA,CDK18,ENPP2,MAPK10,RASGRF1,SELL,PPP1R9A,CCDC88A,SOX10,SP4,IZUMO4,ROBO3,EXOC7,SZT2,PCDHGA1,TEK,HEY2,LILRA4,UGT8,XRCC4,ZNF45,SYNC,NUP214" Drug 4950_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ASIC1,NDRG2,ADRA1D,AGT,AK2,CDK13,ALDH7A1,ADAM23,SGCE,BAIAP3,KALRN,CDH8,HOMER3,PCYT1B,RCHY1,CRMP1,CSF1,RIMS2,MFAP3L,ELAVL2,NRN1,ZNF589,KIAA1109,OLFM1,AGAP2,OGA,GAB1,GAD1,RND1,GLYR1,GNAL,LPAR4,SYNPO,ITIH2,KCNK2,VWA5A,NEUROD1,NOS1,P2RY1,MINDY2,PTHLH,RGS12,KCTD17,KLHDC8A,PNMA8A,RPS6KA2,KCNIP1,CNKSR2,ZNF423,ZBTB43,ATP10B,PHLDB1,PLCB1,POPDC3,PARD3,TRH,TRIO,ZNF711,SPHK2,GDPD5,STMN4" Drug 4427_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ACTN2,SEMA7A,KCNAB2,FAM131A,CDC14B,ASGR1,BRINP2,ATM,BACH1,GYG2,HAP1,SYNGR3,CACNA2D2,AKAP5,NRG2,PDE4DIP,EDRF1,RIMS3,MFAP3L,PLPPR4,SEMA3D,F5,ERAP1,RND1,LILRA2,FAM107A,PADI2,IL6ST,ITGA7,KCNH2,KHK,MMP16,NF1,NPTX1,NRCAM,NTRK3,PCDH9,PDE2A,PIK3R1,PURG,PRKCB,PKN2,PTCH1,SLC25A36,PNMA8A,ASIC4,ZNF334,KDM4B,ZHX3,ZC3H13,NCDN,SYP,MCF2L,KLHL4,TPM3,CA14,HIRA,ZIC3,SPHK2,EVI5,NLRP3" Drug 5794_UP Methazolamide [554-57-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "TTYH1,PPP4R4,ATP6V0A1,KIF1A,BMP7,CACNB2,HAP1,USP2,SCARB1,FOXN3,TPP1,PICK1,WHRN,COL9A2,AKAP5,RIMS2,PYGO1,DCT,HIPK3,EFNB3,PLXNC1,ING4,PLEKHO1,EZH1,CORO2B,KAT8,FLT1,PNMA2,DKK3,SYT17,NEU3,PRUNE2,GRIA4,GRIK5,GRM7,KCNJ3,KCNQ3,AFF1,ADAM22,P2RX7,PTPRB,PID1,ACSS3,CCDC40,TMEM206,RPS6KA2,EMID1,ZNF821,SLA,SLC6A9,SNCA,KDM4B,ZSWIM8,ZBTB43,TACR1,ZMYND8,VAV1,SLC13A3,REEP1,ADAMTS9,KCNAB1" Drug 5975_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "KIDINS220,AP2A2,C1QTNF3,ALK,APBA2,APBB2,GAS7,PPP4R4,CAMK2G,CBFA2T2,BAG4,NCOR2,PDE4DIP,ARHGEF4,USP6NL,RIMS3,MFAP3L,ELAVL2,RASGRP2,CACNG3,PRELID3A,GAD1,GALC,GFAP,GRM1,PTGDR2,INPP5B,ITIH2,KCND3,KCNH2,VWA5A,NPR2,PCBP3,PIK3CD,PACSIN1,POU3F2,MAPK7,RAB3A,RAB3IL1,DCUN1D2,ASIC4,FERMT1,SLC20A2,OGDHL,LIMCH1,DOP1A,EMC1,ZNF423,ST5,MAPK8IP3,JMJD6,WSCD1,KIAA0930,TCF7,DAAM2,PARD3,ZKSCAN5,VAV1,LAMP5,ITM2C,KAT6A" Drug 3032_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ACTN2,SPARCL1,SYT13,PPFIA2,APBA2,PPFIA3,AQP4,ASTN1,RGS11,MYRF,BAIAP3,BRSK2,HIP1R,SEPT7,CHGB,SOCS6,TCEAL2,NCOR2,CNTNAP2,RIMS2,SNPH,DCT,MFAP3L,DMD,SRPK3,NCALD,GABRA1,SIGLEC8,ATP8A2,ALDH1L1,GNG4,GPR37,PCLO,GRIA4,ADAMTS8,AP4S1,HPSE2,SCIN,LAMA2,MX1,MYBPC1,MYCN,OMG,OPCML,OPRL1,MAPK7,PTPN13,PTPRB,SLC6A15,RGS12,MYH14,CCDC92,EPN2,SLC11A1,SOX2,ROBO3,DOCK9,SEZ6L,LMF1,ZBTB16,PLSCR4" Drug 2483_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ACTN2,MRTFA,AMH,BIN1,PKP4,PPFIA3,AQP4,PLA2G4C,MPDZ,BAIAP3,BTRC,NEURL1,SEPT7,CHN2,LHX2,CLCN4,ABI3BP,ENTPD4,CRMP1,DCAF4,MFAP3L,RUSC2,KLHL3,HS3ST2,DTNB,MBNL2,RASGRP2,TBC1D16,KIAA1109,FOXG1,AGAP2,KHDRBS3,DLL3,SEPT9,GATM,GRIN1,FAM107A,SYNPO,HSD17B1,KCNH1,MAP4,LRRN3,GRAMD1C,RAB3IL1,RGS4,CLSTN2,MAPK8IP3,ASTN2,TRIM2,RPGRIP1L,PCDHGA10,PCDHA5,PARD3,TRIO,LMF1,VSNL1,MAP3K12,SLC17A7,KAT6A,SSPN,GAN" Drug 6182_UP nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "APAF1,CCDC181,SLC4A4,CACNA2D1,CACNG1,MAP7,NEURL1,CBARP,ASIC3,CHRNA4,PICK1,NCOR2,MICAL2,DAPK3,NTM,DLG3,TRAPPC9,SEZ6L2,EFNB3,FAM13A,MBNL2,PLXNC1,SORBS3,ELAVL3,MRNIP,VPS13B,STX2,CEND1,OLFM1,FGFR1,BAIAP2,AGAP2,GNAO1,RAPGEF1,GUCY1A2,HTR5A,KCNJ5,KCNJ9,MYH6,NEFM,NF1,SLCO1C1,OPRL1,PDE4D,PFKFB2,PTPRN2,PNMA8A,RASA3,SH3BGR,SH3GL3,FRMPD1,CPEB3,CNKSR2,SLC1A7,PDZD2,ZHX3,ICAM5,RPRM,LMF1,NAV2,JPH3" Drug 2677_UP chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "ADCY2,MRTFA,AMPH,OGT,PPP4R4,CADM3,BTRC,HIP1R,MAP7,CDH10,CHN2,CNN3,FAM149A,WHRN,CPS1,NCOR2,SUSD5,PLCH2,PDE4DIP,USP6NL,EDRF1,MFAP3L,SHANK1,ST8SIA3,EFS,DLC1,AGAP2,PDLIM5,TBR1,GCK,GCNT2,GHR,GNAO1,GNAS,STON1,MCHR1,CACFD1,GRM3,KLF12,BACH2,ITIH2,KCNF1,MMP16,MOBP,NDP,DUSP26,PLCD1,CNNM2,RYR1,SLC11A1,SNAP25,SOX15,INKA2,SYN2,SYT5,CRTC1,PCDHA2,TPM1,TRIO,TRPS1,VSNL1" Drug 2406_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.92E-08 4.37E-03 3.83E-06 4.36E-05 61 199 "PDE8B,ALDH4A1,KCNAB3,ZMYM4,CHGA,CHI3L2,CHRNB2,ZFYVE9,SULT4A1,NCOR2,ABCG1,CTNND1,PHYHIP,ST8SIA3,SEZ6L2,FCF1,OLIG2,MTSS1L,ERBB2,CDKL3,CAP2,ERAP1,GATM,GCNT2,GNG4,FAM107A,ATXN2L,IFI16,KCNJ5,MAG,AFDN,MPP2,MYO7A,NELL2,NPPA,NRCAM,NUMA1,PRKCZ,WDR25,PTK2,PEX5,GAL3ST4,RGS3,GALNT10,KDM4D,SLC20A2,SNCA,KDM4C,PEG10,ATP10B,MAPK8IP3,SYT1,ATP11A,MCF2L,TNS2,CRTC1,PCDHA5,ZNF34,FAM155A,LMF1,XRCC4" Drug 6980_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-08 4.45E-03 3.89E-06 4.42E-05 56 177 "ABHD6,ADD3,NME5,ARNTL,ST3GAL5,SCAPER,SPAG9,CLGN,PDE4DIP,CTH,KIAA0513,ARMCX2,DNAJC6,EFNA3,EFNB3,ENO2,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,DIPK1A,INPP5B,KIF5C,LSS,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,PRPH,LRRC49,SH3GL3,PPM1E,WDR47,CCDC88A,ZCCHC24,SPTAN1,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,HEY1,BEX4,NPL,RUNDC3B,SSBP2,DNAJC12,REEP1,SLC17A7,ITM2C" Drug 1645_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.07E-08 4.45E-03 3.89E-06 4.42E-05 56 177 "ADD3,NME5,ARNTL,MARK4,ST3GAL5,BAIAP3,CLGN,KIAA0513,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,STX2,EXTL2,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,GLS,RAB40B,TDRKH,STON1,RNFT2,KIF5C,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PMP22,PKIA,PRPH,PTCH1,SH3GL3,PPM1E,ASAP3,WDR47,ZCCHC24,KIF21B,ELOVL4,RGL1,STXBP1,ACSBG1,TRIM2,HEY1,BEX4,RUNDC3B,SSBP2,UBE2H,DNAJC12,REEP1,SLC17A7" Drug 7499_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.49E-08 4.65E-03 4.06E-06 4.62E-05 58 186 "ASPHD1,KCNAB2,APLP1,PPFIA3,BMP7,ST3GAL5,BAIAP3,CLGN,PDE4DIP,KIAA0513,DNAJC6,JAKMIP2,OPTN,EFNB3,EIF5,CDKL3,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,RNFT2,SLC2A6,KIF5C,MPP2,NEK1,PCDH9,CDK18,PDE4A,SERPINI1,PIK3CD,PRPH,PTCH1,RAB3A,RPS6KA2,SH3GL3,ASAP3,SYBU,SLC6A8,ZCCHC24,KIF21B,ZBTB43,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TACC1,HEY1,RUNDC3B,CLIP2,SLC30A3,NAV2,SLC17A7" Drug 6051_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.49E-08 4.65E-03 4.06E-06 4.62E-05 58 186 "ASIC1,ALCAM,PDXK,CAPRIN2,ALDH4A1,KIF1A,GYG2,CA12,KYAT1,PLEKHB1,LHX2,RAB26,SH2B1,RASSF2,RIMS3,PARD6A,DPYSL2,EFNA3,STX2,ARMCX1,TBC1D16,TESK2,ZNF589,IQCG,SYT17,SESN1,GLS,RAB40B,GNG4,GRIK5,MAPT,MPP2,SLC25A23,MBOAT7,PKIA,PRKAR1B,RAB5B,RET,RNASEL,SGK1,FAM102A,FAM214B,SHANK2,TMCC1,SPTAN1,VAMP1,ARHGEF9,VPS13A,ASTN2,PSD3,TNS2,TMEM121,ZMAT3,CABIN1,ZMYND8,REEP1,LRP8,MPPE1" Drug 2500_UP Nystatine [1400-61-9]; Up 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "BEGAIN,PKP4,SEMA4G,RASL11B,DDX3Y,ALDH4A1,NRP2,MTMR3,CFAP410,CALB1,SLC16A4,SEPT7,CDO1,EPS15L1,CLU,CRMP1,PDE4DIP,DCAF4,SNPH,CNIH3,MAMLD1,ST8SIA3,HEYL,RASGRP2,FER,PDLIM5,CAMKK2,GPD2,NCKAP1L,ITPKA,AFDN,MOBP,MPP2,NNAT,NTRK2,OMG,PIK3R1,PMP22,RELN,RFX2,PNMA8A,ROM1,HSPA4L,FERMT1,SLCO1A2,SNCA,CAND2,SPP1,ZC3H13,SPTB,MAPK8IP3,PHLDB1,ATP13A2,GPR161,TK2,RBFOX2,CDK20,VIPR2,MKRN3,SSPN" Drug 4232_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ASIC1,NME5,SEMA6A,GAS7,CDK13,ATP2B2,SLC2A11,BMP7,IL33,BTRC,NRXN3,CABP1,HAPLN1,MICAL2,PDE4DIP,RIMS2,CTIF,BRINP1,DBT,SGK2,ZNF391,FGF1,ERGIC3,GAP43,SYT17,TDRKH,CACFD1,ADAMTS8,GRM7,GRM8,AP4S1,ATXN2L,KLF12,ICA1,IL6ST,KIF2A,LSS,ADAM11,NEFM,PDE4D,MAPK8,RET,KLHDC8A,PNMA8A,SCN2B,ZNF334,CDK19,PHLDB1,SYT1,ADGRL3,TBL1X,KLHL4,SZT2,ZNF34,TNS1,CDK20,CADM1,KCNK12,KCNAB1,JPH3" Drug 268_DN genistein; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "CNTNAP1,APOC1,BCAS1,ARNTL,ARSF,CHRD,FGF17,GYG2,CFAP410,CAMK2A,CD86,CDH2,ARHGAP33,TAOK2,COL9A2,CSF1,CHD5,KLHL3,AK5,DRP2,EDIL3,SGK2,EFNB3,LRRC17,EFS,EYA1,CACNG2,GAD2,SEPT9,SRCAP,RUNDC3A,GRIN1,GRM2,RNFT2,NCKAP1L,ATXN2L,C2orf72,TJAP1,KCND3,L1CAM,MBP,MYO7A,MYT1,NCAM1,SEPT4,MASP1,PTPRN,MARCH1,GAL3ST4,EMID1,SLC8A1,SLC11A1,UNC5B,CLSTN2,POGZ,TACR1,CHST8,PLPPR2,VIPR2,SLC13A3" Drug 1884_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "PLA2G6,ALAD,APBB2,APP,PRX,CADM3,KIF1A,CACNA1I,MYRF,CACNA1A,CALB2,CAMK2B,CDH8,CACNA2D2,FOXN3,CHN2,STOML1,CNTFR,SH2B1,CRMP1,NCOR2,KLHL3,EFNB3,SUGP2,SRPK3,ELN,RASGRP2,FGFR1,GAP43,SPACA9,CACFD1,KCNJ3,LAMA2,MBP,GIT1,SAMD14,MYT1,NPPA,OMG,OPRL1,KCNK10,DUSP26,CAMKV,PACSIN1,PPARA,PPP5C,PRKCB,PTH1R,DCUN1D2,SYNDIG1,RXRA,ST6GAL1,BCAN,LIMS2,ZHX3,ZC3H13,PHLDB1,ZMYND8,VGF,WIPF1" Drug 7237_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "FZD9,ADORA1,NME5,AK2,PLA2G6,ANK1,GAS7,MARK4,ATM,KSR1,BTRC,CALB1,USP2,NEURL1,SOCS6,ARMC8,CRY2,CHD5,SDC3,ARHGEF4,GIT2,EXOG,EFNA3,EFNB3,MBNL2,TNK2,DLC1,KAT8,ZNF589,KIAA1109,KHDRBS3,OGA,FYB1,TDRKH,JAK2,KCNC1,KCND3,KIF2A,LIG4,KITLG,MMP16,NF1,OMG,PPP1R1A,GRAMD1C,PROX1,ZSCAN32,RASGRF1,CCDC88A,AJAP1,VAMP1,PLCB1,POPDC3,TCF4,PSD3,TMOD1,HIRA,UBE3A,SPHK2,SSPN" Drug 3478_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "DPF1,NDRG2,SLC4A4,BMP7,GYG2,LDLRAD4,SOCS6,RCHY1,CSF1R,SIPA1L1,ARHGEF4,RIMS2,GPRASP1,DCAF8,DGKG,GIT2,GNE,HIPK3,EGFR,MBNL2,SORBS3,HSD17B14,OLIG2,ACSL4,ZNF589,SCARA3,EFCAB2,TPK1,ERAP1,GPM6A,NR3C1,ELOVL5,INPP5B,MAN2A2,TM6SF1,ADAM22,NF1,NPR2,PDE3B,PLXNB1,PACSIN1,MAPK7,GTDC1,RNASEL,RPS6KA2,PKNOX2,BTBD7,COA1,WDTC1,ZBTB43,SYN2,POPDC3,ROBO3,EXOC7,TBL1X,KIAA0930,SLC44A1,SF1,EMSY,NAV2" Drug 6667_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ADD2,TRMT9B,APAF1,APC,GAS7,ADAM23,LDLRAD4,BTRC,PLEKHB1,CLCN4,ABCG2,RAB26,WHRN,ABCG1,RUSC2,CDON,SGK2,CELSR3,PLEKHO1,LRRC23,EPHA5,VPS26C,FAM49B,PNMA2,FYB1,GNG4,LPAR4,CNTRL,GRIK2,SYNPO,INPP5B,VWA5A,MAPT,TM6SF1,MEIS1,CNOT4,NOVA1,PLXNB1,MAPK7,GRAMD1C,SEC61A2,SUGCT,GSTCD,KIRREL1,TMEM156,SCN8A,SCG5,TSNAXIP1,IQSEC2,TROVE2,NCDN,ASTN2,KIAA1107,AHCYL2,DNAH7,TIAM1,TRIO,XRCC4,TFIP11,NT5M" Drug 4481_DN Amidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ALK,APBB1,PPFIA3,SEMA4G,CDK5R1,SCAPER,BTRC,CCNT1,CBFA2T2,ARHGEF2,ARHGAP33,CHN2,LY86,IQCK,CREM,AATK,SPOCK3,TMCC2,DTNA,CNNM1,EIF5,COQ7,SPEG,SCML2,SEC23B,ATP2C1,CGREF1,C1QL1,POLL,GPR19,MUM1,BACH2,IFI16,SHISAL1,IL11RA,KIF5C,MAPT,MED1,MAPK8,BCAS3,PTHLH,PTPRE,TMEM231,RAB3A,ATG16L1,RGS7,TTLL7,PAQR6,MAPK12,KBTBD4,KDM4C,BEX1,NXT2,SYT1,DICER1,TGFBR3,BEX4,TNS1,TRPC1,ZNF711" Drug 2260_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "FZD9,TRMT9B,CDC42BPA,ASPH,SLC2A11,ADAM15,ADGRB2,CACNG1,CAMK2B,CDC42,FADS2,DNAJB5,CNR1,CRY2,CHD5,CNTNAP2,TBC1D5,MAGI2,NTM,ATN1,EIF4G2,RASGRP2,IGSF6,DLC1,ST3GAL6,ZNF589,FGFR1,FGFR3,NSG1,GAB1,GABRG2,GRM8,KCND3,MID1,MMP17,PFKFB2,PTAFR,CCDC40,TCP11L1,KCNIP1,FNDC3A,SLC11A1,BTBD7,SLCO1A2,SMARCA4,SNAP25,FAIM2,SOX2,IZUMO4,HECW1,PSD3,TEX15,TNS1,TRPC1,UCHL1,OSBP2,PRDM2,NT5M,PRDM10,ITM2C" Drug 4366_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "NDRG2,C1QTNF1,KCNAB2,ASCL1,SYNJ2,CDH2,CHI3L2,TAOK2,TPP1,CNTN1,MICAL2,SPOCK3,EDNRB,SGK2,EGFR,PLXNC1,EN2,KCNMB2,ST3GAL6,DISC1,GFAP,MSL3,GNAO1,GNG4,GPM6B,RASSF8,HRH3,HPSE2,IFI16,KCNC1,KCNH2,KCNK2,MATN3,MYCN,NPY,PCSK1,PGAM2,PIK3CD,CEP41,PTAFR,PTPRZ1,RAD52,RASGRF1,KHDRBS2,GAL3ST4,RFX2,ZC3H13,CDK19,SYT11,SYP,POPDC3,TCF4,TRO,HIRA,FLRT2,WIPF1,LAT2,ETNPPL,SCG2,SLC17A7" Drug 4194_UP Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "NDRG2,BEGAIN,APAF1,PDXK,FUBP1,SCAPER,MYRF,LDB2,CDC42,MAGI1,FOXN3,STOML1,HOMER3,IFFO1,CTH,SPOCK2,NRN1,PTK2B,GALC,DISC1,TDRKH,STON1,GRM2,PTGDR2,HTR2A,KIT,MEF2C,LYRM9,NF1,PCBP3,NTRK2,PDGFRA,ENPP2,GPR85,PFKFB2,POU3F2,LRRN3,PRKAR1B,GAL3ST4,RGS4,RGS7,TMEM206,SEMA6D,STUM,SUPT20H,SH3BP2,DZIP1,SNCA,SP4,SPTB,MCF2L2,SYT11,SYN2,KIAA1107,PCDHGB6,DAAM2,CADM1,LMF1,WIPF1,WNK1" Drug 4167_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "NDRG2,ADRA1D,MRTFA,AMPD3,EPB41L5,GAS7,MARK4,SGCE,CFAP410,CA4,SPAG9,NEURL1,FOXN3,ZFYVE9,PDE4DIP,FAM169A,DCAF4,NOS1AP,TBC1D5,SPOCK2,SRGAP3,DYRK1A,EFNA3,PLXNC1,ELN,VPS13B,ERCC2,KIAA1109,SEPT9,LYVE1,GLYR1,MSL3,CACFD1,INPP5B,KCNN1,LSS,MDM4,KITLG,MPP2,MYT1,NEUROD1,NF1,MBOAT7,PRKCB,RGS10,GSTCD,SH3BP2,ASAP3,RPH3A,PREX2,LIMS2,THSD1,PLCB1,SYT5,CRTC1,CHST8,AP4E1,TGFBR3,TRPM2,KAT6A" Drug 3669_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "MTUS1,NME5,PLA2G6,LTBP4,ARHGDIG,BRINP2,ATP6V0A1,ADAM23,MAP7,CSF1R,CNTNAP2,NOS1AP,ARHGAP24,RIMS3,BRINP1,SPOCK3,ARNT2,EXOG,ATN1,ECM2,ING4,RGS17,KCNMB2,PIPOX,F5,HPCAL4,NSG1,GABRG2,SIGLEC8,RUNDC3A,GNAO1,GPM6B,GRIK2,SOX21,NXPH3,HSF2,ICA1,LYRM9,NELL2,PDE4B,PIK3CD,SMOX,PTHLH,PID1,RORB,SALL1,SLC1A2,SLC1A7,SLCO1A2,LMO3,ATP10B,SYN2,TBL1X,PCDHA5,TPM3,TRPC3,ZMYND8,SLC30A3,KCNAB1,NLRP3" Drug 2132_UP Xylazine [7361-61-7]; Up 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ACTN2,ADORA1,ANK1,CNTNAP1,ARHGDIG,GYG2,CACNA1D,MAP7,CHI3L2,JAM2,AKAP7,SLC4A7,CPS1,RIPOR2,RUSC2,PARD6A,DSCAM,MBNL2,MTSS1L,STX2,F5,HPCAL4,NBEA,ALDH1L1,GFER,RUNDC3A,GPR19,GRM1,KHK,MAP4,MEF2C,MYO7A,NUMA1,PENK,EPB41L4B,PPP2R2B,PTAFR,PLPPR1,RIPOR1,FAT4,GAL3ST4,RAVER2,RYR1,ZNF821,ZNF365,MYH15,VAMP1,CAMSAP2,TBCEL,PSD3,OBSL1,TEX15,TK2,ICAM5,KCTD2,CDK20,RUNDC3B,ZMYND8,UCHL1,ZFP37" Drug 4971_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "NDRG2,SPARCL1,PPFIA3,ARRB1,SLC2A11,ALDH7A1,BTRC,CACNB2,CAST,CCKBR,HOMER3,CNTN1,FAM149A,WHRN,VCAN,GREB1,EDRF1,RIMS3,MFAP3L,SIDT2,ZNF589,FGF1,CAMSAP1,AGAP2,ALDH1L1,GFER,RND1,GLYR1,MSL3,GPM6B,GSTM5,KCNH2,KIT,VWA5A,LSS,MEF2C,NUCB1,RETREG1,NLE1,PLEC,NECAB2,RETREG2,PPP5C,ZFHX4,CARF,WDTC1,HECW1,ZBTB43,ST5,POPDC3,KAZN,WSCD1,TCF7L2,TRIO,ZMYND8,HIRA,ZBTB14,SPHK2,SSPN,SENP7" Drug 6159_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "NDRG2,PLA2G6,C1QTNF3,ALK,CDC42BPA,AQP6,CDK10,ATP6V0A1,ADGRB1,MPDZ,MTMR3,LDLRAD4,HAP1,RUNX1T1,CBFA2T2,CHGA,CHRNB2,CREM,SPOCK2,E2F5,SIDT2,EFNA3,EGR3,SRPK3,RASGRP2,MTSS1L,KCNMB2,ERCC2,FHL1,FLT1,GPR153,GLS,GRM7,IL1RAPL1,SCIN,KCNMA1,KCNN1,MOBP,MSI1,NOS1,NPY,NRCAM,MAPK10,BCAS3,CRTAC1,FRMPD1,SHANK2,CXXC4,KDM4B,ACSBG1,ROBO3,MCF2L,WWC1,WSCD1,CRB1,BEST1,TRIM9,SLC17A7,KCNAB1,PCBP4" Drug 6662_UP Fluspirilen [1841-19-6]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "RALGAPA1,ACTN2,ADORA2A,AK2,PPP4R4,CDK13,PDE8B,ATM,ATP2B2,CFLAR,KALRN,HAP1,SLC16A4,SCARB1,LARGE1,DLGAP2,EPS15L1,CLCN4,SULT4A1,EDRF1,RIPOR2,SPOCK2,MFAP3L,MAGI2,NTM,DLG4,PLEKHO1,EPHB1,ETV1,DLC1,SEMA6C,SORBS1,OGA,PCDH17,GRM3,GSTM5,KCND3,KCNJ5,KCNQ3,ADAM22,MT1M,NCAM1,NPR2,NTRK2,OPRL1,PCSK2,GPR85,PTAFR,TCP11L1,ASIC4,SLC12A4,ZNF334,HECW1,ZC3H13,TACR1,MCF2L,CRTC1,ICAM5,SPHK2,KCNAB1" Drug 7361_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ABHD6,NDRG2,PPP4R4,MARK4,NCOA1,ALDH4A1,ATP2A2,KIF1A,SYNJ2,SCAPER,RAB29,CACNA1D,CACNG1,CCKBR,ARHGEF2,CRLF1,B4GALT6,HOMER3,CNTFR,CSF1R,FEZ1,SIPA1L1,DNAJC6,RABGAP1L,KBTBD11,DSCAM,GNE,TNK2,LRRC23,ZNF589,GNG3,PRUNE2,PADI2,ATXN2L,DHX35,KCNMA1,MATN3,NOS1,NPTX1,PAX6,PC,PRODH,SAMD9,GON4L,RAD52,C1orf54,SBF1,PPM1E,FAM214B,SOX3,ZCCHC24,TROVE2,ARHGEF9,PLCB1,AP4E1,CABIN1,PLPPR2,ZNF74,HPS4,ST7" Drug 5910_DN estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ASPHD1,ABHD6,ADRA1D,PLA2G6,TRMT9B,ANK1,APBB2,PPFIA3,CDK13,BRINP2,CCDC181,ATP2A2,ADAM15,CSF1,FAM131B,DAPK3,CTIF,MFAP3L,SGSM2,CHRDL1,DLG3,ELAVL2,EN2,NCALD,PIPOX,ABCA8,OLFM1,ANKFY1,PRELID3A,FYB1,HBS1L,ERAP1,GLRB,IL6R,MMP16,ADAM22,PCDH9,PDE4A,GPR85,GAL3ST4,RGS12,MRAS,CCDC88A,SNCA,RBM34,WDTC1,TSNAXIP1,SPTB,THSD1,SS18,MAPK8IP3,COBL,EXOC7,DICER1,ICAM5,TRPC3,ZMYND8,VAV2,REEP1,TFIP11" Drug 4263_UP Primaquine diphosphate [63-45-6]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-08 4.79E-03 4.11E-06 4.67E-05 60 195 "ABAT,BBOX1,PPP4R4,ASTN1,B3GALT2,SYNJ2,LDLRAD4,RUNX1T1,CHGA,NDST3,NRXN2,AKAP6,CSF1,EDRF1,CX3CR1,BRINP1,DRP2,ABCC9,EDN3,ERBB4,HPCAL4,EFCAB2,PDLIM5,SIGLEC8,GFER,CSDC2,GRIK3,FAM107A,HTR5A,IGSF1,KCNC1,LSAMP,MOBP,ADAM22,MYT1,NCAM1,NELL2,NTRK3,P2RX7,RETREG1,ST8SIA5,NECAB2,MARCH1,C1orf54,RASGRF1,KHDRBS2,RGS4,RYR3,SLC6A11,IZUMO4,ZBTB43,VAMP1,TF,TK2,TPM2,TRPC3,CADM1,WIPF1,KCNK12,NLRP3" Drug CID000001206 MAMP Stitch 9.82E-08 4.81E-03 4.12E-06 4.69E-05 52 160 "ADCY5,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,ATM,CALM1,CCK,AIFM1,CRY2,CSNK1E,MED12,DPYSL2,DRD1,NCALD,PPP1R1B,FOXM1,GABRG2,GFAP,LOXL3,GRIK1,GRIN2C,GRIN2D,GRM2,GRM5,HRH3,MAOB,MAPT,MTR,NOS1,NPY,OPRL1,PAH,PDE1B,PDYN,PENK,PPP3CC,GSTCD,SLC1A2,SNCA,SOX10,DDN,ADHFE1,SYT4,TACR1,ZEB1,WDR7,ZMAT3,CSMD1,TRH,SLC17A7" Drug 1050_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 9.82E-08 4.81E-03 4.12E-06 4.69E-05 55 173 "ADD3,ALAD,ARNTL,BMP7,ST3GAL5,RAB29,KYAT1,KIAA0513,RIMS3,ARMCX2,DNAJC6,TSPAN5,OPTN,EFNA3,EFNB3,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,FYN,GLS,RAB40B,STON1,RNFT2,PADI2,DIPK1A,KIF5C,MXI1,NEK1,PCDH9,PMP22,PKIA,PRPH,LRRC49,SGK1,SH3BGR,SH3GL3,PPM1E,WDR47,ZCCHC24,ZBTB43,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,RUNDC3B,SSBP2,UBE2H,DNAJC12,NDRG4,REEP1" Drug CID004489307 AC1NB8R3 Stitch 9.94E-08 4.87E-03 4.17E-06 4.74E-05 64 213 "NLGN4X,ATM,CCKBR,NRXN3,NRXN1,CNR1,CST3,EXOG,DYNC1I1,ATN1,EN2,VPS13B,PPP1R1B,FOXG1,AFF2,COQ5,GAA,GABRA4,GABRB3,TCERG1,GRIA1,GRIK1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PACSIN2,HNRNPK,TLX1,HP,HPR,LIG4,LMO2,MAP4,AFF1,MYCN,NOVA1,NOVA2,HCN1,PAH,PDGFRA,PENK,ABCB1,NLGN3,PACSIN1,SH3KBP1,PYGM,ATXN7,FOXRED1,ASRGL1,MRAS,SLC1A2,SLC1A3,BEX1,ARHGEF12,CYB561A3,TTPA,UGT8,ZBTB14,FXR1,JPH3" Drug 6879_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.03E-07 5.06E-03 4.33E-06 4.92E-05 57 182 "ASPHD1,ST3GAL5,BAIAP3,USP2,CLGN,WHRN,DOCK4,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,OPTN,EFNA3,EFNB3,STX2,F3,TUBB4A,BAIAP2,DPYSL4,FYN,CYP46A1,C1QL1,RND1,GLS,RAB40B,STON1,KIF3A,KIF5C,MPP2,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PRPH,LRRC49,RPS6KA2,SH3GL3,WDR47,PKNOX2,ZCCHC24,SOX15,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,TRIM2,HEY1,RUNDC3B,DNAJC12,GDPD5,NAV2,SLC17A7,ITM2C" Drug 1000_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.06E-07 5.20E-03 4.44E-06 5.05E-05 54 169 "ADD3,NME5,ST3GAL5,BAIAP3,CLGN,PDE4DIP,KIAA0513,RIMS3,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,STX2,TUBB4A,BAIAP2,DPYSL4,GPR153,FYN,CYP46A1,RND1,GLS,RAB40B,STON1,KIF5C,MPP2,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,MAPK8,PRPH,PTCH1,RAB3A,RPS6KA2,SH3BGR,SH3GL3,WDR47,ZCCHC24,KIF21B,THSD1,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TRIM2,HEY1,RUNDC3B,SSBP2,DNAJC12,SLC17A7" Drug CID000003019 diazoxide Stitch 1.07E-07 5.25E-03 4.47E-06 5.09E-05 67 227 "KCNAB2,ATP1A1,CA4,CACNA2D1,SLC5A11,CBFA2T2,SLC32A1,ABCC9,TUBD1,KCNMB2,TUBB3,TUBB4A,FOXM1,GART,GCK,GCNT2,TUBA8,KCNMB4,GPT2,GPD2,TUBA1C,GRIA1,GRIA2,GRIA4,GRM3,HMX1,TUBB2B,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNF1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NPPA,KCNK10,PRKCB,PRKCG,RIT2,SST,ABCC8,KCNE5,TUBB2A,TUBB1,KCNT2,MFF,TUBA1A,KCNAB1" Drug 2148_UP Boldine [476-70-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ABAT,MTUS1,BIN1,APAF1,ARNTL,ATP6V0A1,BTRC,MAP7,SLC16A4,SEPT7,CLGN,SOCS6,SULT4A1,CNTFR,CREM,CRMP1,PDE4DIP,TMCC2,SHANK1,EEF1A2,EIF1,OLIG2,TUBB4A,PDLIM5,CAMKK2,ERAP1,ALDH1L1,SRCAP,RUNDC3A,ZNF276,GPR19,GRIK5,AP4S1,PADI2,PTGDR2,IL12A,ITPKA,KIF5C,CD200,ZNF862,NUMA1,SETD4,PENK,LRP12,PPP5C,BCAS3,PTPRN2,SLC9A5,RBM34,SPTAN1,CDK19,SEPT8,CEP68,CAMSAP2,TBCEL,CDK20,ZMYND8,ZFP37,SPHK2,TFIP11,TIGD6" Drug 7046_DN PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "APOC1,APP,MARK4,SLC2A11,ALDH7A1,ATP6V0A1,NRP2,CDK5R1,SCAPER,IL33,MAP7,SCARB1,ARHGEF2,PLEKHB1,CNOT8,TAOK2,NMT2,WHRN,COL9A3,SLC4A7,CSF1,CSNK1E,PDE4DIP,FAM131B,CNIH3,PARD6A,DNM2,DSCAM,EDIL3,COQ7,RRAGB,BAIAP2,GABRA2,GAD1,ERAP1,SYT17,ARFIP1,ATXN2L,KCNMA1,LIFR,PDPK1,ZNF426,SYTL2,ELOVL2,RAD52,RPS20,FAM102A,AMBRA1,SLC1A7,IFT122,TNIK,FCHO1,JMJD6,FBXW11,TCF4,TIAM1,TK2,TNS1,RBFOX2,METTL3,MPPE1" Drug 6613_UP Theobromine [83-67-0]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ADRA1D,ADGRF5,C1QTNF3,MRTFA,KCNAB2,APBB2,GAS7,ATP6V0A1,FUBP1,KALRN,RUNX1T1,ARHGAP33,ADGRG1,CHRNB2,SMG7,CHRDL1,EDNRB,IRAK4,ETV1,ANKMY1,REEP2,FOXG1,GAB1,GALC,GPM6A,RAPGEF4,ADAMTS13,KCNN1,KIFC3,KIT,MOBP,CTNNA3,NOVA2,NPR2,PCDH9,PENK,PROX1,PTPRB,C1orf54,RGS4,FBXW7,IL17RB,ASAP3,CPEB3,SLC11A1,TNIK,KDM4C,SPTB,SYT5,KAZN,TPM2,CHST5,PRMT8,TRIO,RUNDC3B,HIRA,ZNF24,ZNF74,SLC17A7,KCNAB1,NLRP3" Drug 3276_DN Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ALK,MRTFA,GAS7,FAM131A,APOC1,BCAS1,ARRB1,ASPH,CFLAR,CA4,LHX2,FADS2,NECTIN3,GREB1,DCAF4,DAPK3,DSCAM,TOM1,EDNRA,EFNB3,COQ7,C1orf61,PRELID3A,GPR153,HBS1L,DISC1,EML4,TJAP1,IGSF1,INPP5B,KIF2A,MAP4,TM6SF1,GIT1,ADAM22,NPR2,RETREG1,RGS12,RNASEL,RPS6KA2,WLS,KCNIP1,SBF1,RASA3,ANKRD6,SIRT2,BTBD7,EMC1,CLASP2,CLSTN2,PLCB1,ATP11A,SLC44A1,TRIO,TRPC1,PLPPR2,VAV1,WIPF1,KCNAB1,EPM2A,ST7" Drug 3176_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "SYN3,ARID1A,ANK2,APLP1,APP,ARHGDIG,ATP1A3,AZGP1,SLC16A4,NEURL1,DGKI,RAB33A,CLCN4,NRXN1,LY86,CNN3,CNR1,SLC4A8,CNTNAP2,HEPH,KLHL3,DUSP9,ST8SIA3,EDNRB,SGK2,EPB41,CACNG3,ACSL4,AGAP2,FYN,SEPT9,MYOZ2,SRCAP,CSDC2,LILRA2,GRIN1,HAS2,HPCA,KPNA5,MDFI,NOVA2,CLDN11,RERGL,SYNDIG1,SCN2B,ZFP2,SLA,SHANK2,TSNAXIP1,DOK5,SYT11,PLCB1,SYN2,ADGRL3,PCDHGB6,DNAH7,PIK3R5,SEZ6L,OSBP2,LAT2,MKRN3" Drug 5804_DN Lidoflazine [3416-26-0]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "PLA2G6,ANK3,PDE8B,ALDH7A1,CDK5R1,RAB29,CDC42,LARGE1,PLEKHB1,KIAA1549L,AKAP7,SLC4A8,ABI3BP,PDE4DIP,PHF14,DPH1,EIF5,FER,SEPT9,SRCAP,MSL3,TDRKH,GPR19,TJAP1,KIF2A,MAP4,LYRM9,NUMA1,ODF2,PBX1,CCSER2,NLE1,MAPK7,PRPH,SAMD9,APTX,SH3TC2,FAT4,RGS10,ZNF671,RPS6KA2,SUPT20H,AMBRA1,FBXO11,CAND2,SPTAN1,TROVE2,CEP68,PHLDB1,SYN2,MCF2L,KIAA0930,DNAH7,TIAM1,CADM1,UGT8,VIPR2,LMF1,ZNF74,NAV3,KAT6A" Drug 3882_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "BIN1,APAF1,APC,APOC1,CDC14B,PRX,PPP4R4,ADAM23,KSR1,CFAP410,CACNB2,CALB1,CAMK2B,FOXN3,ZFYVE9,WHRN,COL9A3,DCAF4,SNPH,SPOCK2,BRINP1,MFAP3L,RUSC2,DYRK1A,SORBS3,EPHB1,SPEG,CORO2B,DLC1,FGFR3,BAIAP2,OGA,GLYR1,GNAO1,GNG4,KLF12,ITPKA,KCND3,KCNN2,LSS,MEF2C,AFDN,OPCML,PAK3,PDE1C,RETREG1,MAPK7,RAB3IL1,SH3BP2,CPEB3,EMC1,THSD1,NCDN,AJAP1,DICER1,TMPO,TPM2,TTPA,UBE3A,VAV2,SPHK2" Drug 2323_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ADORA1,AP2A2,APC,GAS7,ALDH4A1,ADAM23,ADAM15,AZGP1,CFLAR,BTRC,CFAP410,LDB2,NEURL1,GPR37L1,CLU,VAX2,CPS1,SNCAIP,RIPOR2,DUSP9,DYRK1A,HIPK3,ELN,SPEG,ANKMY1,PTK2B,FGFR1,FHL1,NEU3,SRCAP,GPD1,TDRKH,GRM8,ITIH2,KIT,LSS,NF1,NNAT,NUMA1,PLCD1,C19orf57,PPARA,MAPK8,MAPK10,CCDC40,SLC30A10,SELL,SLC6A8,CCDC88A,SHANK2,SPTB,MAPK8IP3,TAC3,ATP11A,THBS4,TMOD1,TNS1,SEZ6L,CHST5,DNALI1,ADAMTS9" Drug 3398_UP Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "NDRG2,ADCY2,ADORA3,KIDINS220,MRTFA,BEGAIN,KCNAB2,ATP1A2,GYG2,CACNA1I,CAMK2B,CDH8,PLEKHB1,RAB33A,COL9A3,DAPK3,RUSC2,EFNB3,ELAVL3,ERCC2,PIPOX,F5,PTK2B,FGFR1,FHL1,DLL3,GDF9,C1QL1,ATF7,NR3C1,GRM7,GSN,HLF,HPSE2,TJAP1,KCNMA1,MAN2A2,MEF2C,AFDN,MX1,NNAT,NPR2,NTRK3,OMG,PCDH8,GPR85,MAPK8,PTHLH,ZDHHC14,SBF1,ASAP3,HKDC1,ST6GAL1,OGDHL,KDM4B,JMJD6,VAMP1,SZT2,CHST5,TIGD6,SENP7" Drug 4959_DN Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "RBM10,AK2,APC,BCAS1,CDK13,SCAPER,FOXN3,CLCN3,NMT2,QKI,RAB26,SLC4A8,C2CD2L,MAMLD1,EFNA3,SORBS3,MRNIP,ENO2,EZH1,EFEMP1,PRKAG2,DPYSL4,PRELID3A,B4GALNT1,CRCP,CACFD1,MUM1,HSD17B1,JAK2,KIF5C,IPO5,KITLG,NF1,NPR2,PLCD1,PRKAR1B,CNNM2,ELOVL2,SUSD4,ZCWPW1,RNASEL,ATXN2,SMTN,LIMCH1,NCDN,MAPK8IP3,STX1A,ARHGEF9,EXOC7,CAMSAP2,RPGRIP1L,PARD3,TPD52,TRIO,RUNDC3B,UBTF,VAV1,WNK1,MPPE1,ST7,SSPN" Drug 4469_UP Stachydrine hydrochloride; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "AP2A2,AMPD3,GAS7,SLC2A11,RGS11,NRP2,BRSK2,CHN2,EPS15L1,DNAJB5,IFFO1,RIMS2,C2CD2L,KIAA0319,ARNT2,EDNRA,ELN,LRRC23,REEP2,KAT8,FGF1,FGF12,C1orf61,GAB1,SIGLEC8,GLI2,GLS,PRUNE2,TDRKH,ADAMTS13,KLF12,IL6R,ITGA7,KCNN1,CD200,ADAM22,MSR1,PFKFB4,SPATA6,DCHS2,PTPRH,PTPRN2,RGR,RGS3,PRR5L,KCNIP1,SLC2A5,PKNOX2,SLC11A1,SLCO1A2,SOX15,ZHX3,SYT5,SEMA4A,TNS1,PRMT8,VAV1,VIPR2,PRDM10,KCNAB1,PAK5" Drug 4505_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "PLA2G6,BIN1,CDC42BPA,APC,ASPH,SLC4A4,BACH1,SCAPER,CACNA1I,IL33,BTRC,CFAP410,CAST,SYNGR3,PLPPR4,STX2,ETV1,CGREF1,GAB1,GAD1,B4GALNT1,GNG4,TDRKH,GPR37,KLF12,IL6R,IL6ST,KCNJ5,KIF2A,MDM4,MEF2C,ZNF862,NDP,NFIX,NPR2,NUMA1,PIK3R1,POU3F2,PPARA,PLPPR1,FAM120C,CSRNP3,SUPT20H,FBXO11,PPP4R3A,ZNF667,WDTC1,BEX1,ARHGAP26,IQSEC2,TROVE2,COLGALT2,VPS13A,COBL,KAZN,TMPO,R3HDM1,TRPC1,FAM155A,XRCC4,EVI5" Drug 3079_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ADORA1,AMH,CDC42BPA,SEMA7A,CNTNAP1,CDC14B,DNAH17,CA8,CACNA2D1,KALRN,REPS2,CHN2,ABCG1,RIMS2,USP6NL,SPOCK2,RUSC2,AK5,SUGP2,PLEKHA1,ELAVL3,STX2,FGF13,CAMSAP1,CHL1,GAP43,SIGLEC8,CPLX2,MSL3,KCNMB4,GRM7,HNMT,KCNMA1,MAP4,MOBP,GIT1,TAGLN3,PFKFB4,CAMKV,CCSER2,MTRF1L,CEP41,ACSM5,NKAIN1,RPS20,ZNF365,SLC1A3,EPN2,SMTN,CXXC4,SNAP25,RBM34,ZFR2,TAC3,MTCL1,CUX2,RPGRIP1L,SLC19A3,TRPC1,KCNE5,JPH3" Drug 3968_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "DPF1,C1QTNF1,LTBP4,BIN1,ASTN1,CADM3,RUNX1T1,KYAT1,INA,STOML1,WHRN,CRY2,NCOR2,AATK,CSF1,VCAN,HEPH,RCAN1,USH1C,EDIL3,RASGRP2,RASL12,F5,ALDH1L1,PCDH17,ICA1,LSS,MARK1,MMP16,CD200,NCF2,NTRK2,ENPP2,EPN1,NECAB2,PACSIN1,DIRAS2,CNTLN,PTAFR,MARCH1,PNMA8A,ZFP2,STUM,SH3BP2,CNKSR2,ARHGAP26,JMJD6,PCDHGA10,DOCK9,THBS4,HEY2,TMOD1,R3HDM1,TNS1,OSBP2,CLIP2,LAT2,KCNAB1,PCBP4,PAK5,CAMK1G" Drug 6659_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ASPHD1,ACHE,FAM135A,PPFIA4,ARHGDIG,PDE8B,SLC4A4,CACNA1D,RUNX1T1,CHRNA4,DNAJB5,FAM149A,CREM,ARHGEF10,CTNND2,RIMS2,INTS1,DGKG,ZEB2,C2CD2L,MAGI2,AK5,DSCAM,EDN1,EFNB3,TNK2,EPHB1,NRN1,F5,NEU3,C1QL1,GPR75,CACFD1,HPCA,HTR2A,SHISAL1,KCNB1,KCND3,KCNMA1,NRCAM,OPCML,PALM,CDK18,PDE4B,PDGFRA,ACSS3,KHDRBS2,RET,FOXRED2,FRMPD1,ZNF334,SNCA,ZHX3,ACSBG1,MLC1,SYT5,ZFPM2,TRPC1,SLC17A7,KCNAB1,AP3B2" Drug 3328_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ADCY6,ADORA1,GAS7,RGS11,KSR1,TPP1,CPS1,CSF1,RIMS2,SPOCK2,DBT,EFNB3,ERCC2,ZNF589,FHL1,GABRA2,DISC1,GLRB,GNAL,GRK4,GUCY1A2,IRAK3,INPP5B,KCNB1,AFDN,MOBP,TAGLN3,MX1,MYT1,NF1,NTRK2,KCNK10,SNTG1,PALM,PDGFRA,ENPP2,CAMKV,SAMD9,ZDHHC14,TRIM68,ZFHX4,MYH14,RORB,SYNDIG1,ASAP3,SLC1A2,SLC1A7,SNCA,KDM4B,DOK5,ZC3H13,ARHGAP26,MAPK8IP3,HIF3A,CHST5,TRPC3,KCNE5,FAM155A,SLC30A3,SLC17A7,MVB12B" Drug 6839_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "NDRG2,MRTFA,AMPH,GAS7,SEMA4G,ASPH,SLC4A4,SLC2A11,LDLRAD4,CACNA1A,HIP1R,NEURL1,ADGRG1,EPS15L1,TMEM59L,SULT4A1,CTIF,CNIH3,RUSC2,MAGI2,NTM,CDON,EDNRA,HIPK3,MBNL2,COQ7,ERCC2,ZNF44,GABRA5,SIGLEC8,GCNT2,GNAS,LPAR4,PCLO,GUCY1A2,TJAP1,ITPKB,VWA5A,MEF2C,MID1,MOBP,MSI1,ADAM22,ZNF862,CAMKV,LRRN3,RIPOR1,TMEM231,RFX2,MYH14,TCP11L1,ASAP3,WDTC1,ZCCHC24,HECW1,AJAP1,WSCD1,PSD3,AHCYL2,TMOD1,ZKSCAN5" Drug 317_DN N-phenylanthranilic acid; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "AMPH,APBB1,APC,GAS7,ARNTL,ASCL1,ATP6V0A1,ARHGEF7,CD86,CD38,B4GALT6,ARHGEF6,SLC4A7,IFFO1,SH2B1,CSF1,CSNK1E,DMD,DRP2,EDNRA,EFNB3,C3orf18,F3,TBR1,GABRB1,HBS1L,IQGAP2,GLS,GNAO1,GRK4,GRIK1,GRIN1,GRM2,BTN2A1,KCNC1,MBD1,FXYD7,NOVA2,NTRK3,OPRL1,PPP2R2B,MTMR10,RAB3A,SH3TC2,RGS4,SLC9A5,CDK5RAP2,IFT122,TMCC1,ZCCHC24,IZUMO4,SPTAN1,CLSTN2,KAZN,TEK,THRA,FLRT2,XRCC4,REEP1,MPPE1,NUP214" Drug 5626_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "DPF1,PPFIA2,APAF1,APBA2,GAS7,HIP1R,CLDN10,USP2,TAOK2,QKI,CNN3,CPS1,CREM,CSF1,EDNRA,EFNB3,EGFR,EN2,EZH1,REEP2,AGAP2,SORBS1,NSG1,GNAO1,GSTM5,GUCY1B1,SYNPO,ICA1,KCNN1,VWA5A,MDFI,AFDN,MYH6,CNOT4,PCSK2,NECAB2,MAPK10,GON4L,PTAFR,RGS3,RGS12,TTLL7,MYH14,LIMCH1,SNCA,KIF13A,FAIM2,KIF21B,TSNAXIP1,PEG10,ATP10B,RGL1,SYT5,POPDC3,ROBO3,RPGRIP1L,SLC35G2,XRCC4,SPHK2,UPF3A,MVB12B" Drug 5735_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "AP2A2,AGT,SEMA7A,PKP4,APBB2,CDK10,MARK4,PTCH2,ALDH4A1,ST3GAL5,LDB2,CLCN4,ABCG2,HOMER3,WHRN,ST18,DAPK3,SPOCK2,CTIF,BRINP1,DBT,ELMO1,ECM2,HIPK3,PLXNC1,EN2,CDKL3,FGF1,FGF12,ALDH1L1,LILRA2,GPR19,C2orf72,INPP5B,KIT,LMO1,MAPT,MATN3,MX1,NF1,NOVA1,OPCML,PALM,PDE4D,PFKFB2,TNPO2,LRRN3,MAPK10,PTN,RGS10,DZIP1,PKNOX2,SHANK2,ZNF334,WDTC1,ZC3H13,SPTAN1,IQSEC2,SYN2,CDK20,SSBP2" Drug 3081_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.09E-07 5.34E-03 4.47E-06 5.09E-05 61 200 "ABHD6,ANK3,DNAH17,MPDZ,BCL7A,CACNB4,CHI3L2,EPS15L1,RAB26,HOMER3,FAM149A,TCEAL2,NCOR2,ABCG1,AATK,SLITRK5,EDRF1,PHYHIP,KLHL3,SPOCK3,TMCC2,EDIL3,SEZ6L2,EFNB3,CELSR3,C3orf18,EFS,DLC1,C1orf61,ZNF44,HPGDS,PRUNE2,PCLO,GRIK1,KLF12,KIT,MEF2C,AFDN,TAGLN3,MYO6,SLC11A2,PURG,LRRN3,MAPK3,FAM120C,MARCH1,RAB3A,RASGRF1,ZDHHC14,TTLL7,ZFHX4,BAALC,RPH3A,ZC3H13,TK2,TNS1,TUBB1,VIPR2,CLIP2,MAP3K12,KCNAB1" Drug ctd:D008558 Melphalan CTD 1.09E-07 5.34E-03 4.48E-06 5.09E-05 78 278 "MTA3,HECW2,CC2D2A,ALAD,ARHGAP20,CDC14B,RASL11B,ATP2B1,BCHE,DST,LURAP1,KALRN,RUNX1T1,ZNF521,NRG2,CREB5,SOCS5,RIPOR2,ARHGAP24,TOX,DLG3,EBF1,SNX29,EDN1,FRY,EFNA2,EMX2,EPHA5,MEX3B,NOP56,TACC2,PDLIM5,RASL10A,GAB1,DBF4,PRUNE2,FUT10,GRIN2C,MFSD2A,KLF12,IL12A,JAK2,ARHGAP12,KITLG,MITF,JAKMIP3,RSPO2,NFIA,PIK3R1,PPP2R2B,MAPK3,PXK,PTPRG,ATG16L1,FAT4,ENOX1,RADX,REV3L,FIGN,ZFHX4,SEMA6D,SCN8A,TNFRSF19,SGK1,SHANK2,SLC14A1,TET1,TRERF1,SPATA7,RGL1,FGD4,ANKRD28,MTCL1,KIAA1107,PSD3,TLR4,RGMB,FMN2" Drug ctd:C010902 decabromobiphenyl ether CTD 1.09E-07 5.36E-03 4.49E-06 5.11E-05 324 1582 "CPNE2,ACHE,GPRIN1,ADCY5,HHATL,RNF150,OSBPL1A,CC2D2A,PLA2G6,TAOK1,ADGRF5,BBOX1,KCNT1,BEGAIN,CDC42BPA,ANK1,CCDC146,USP28,GPAM,CACHD1,APP,AQP4,ASCL1,ASPA,ASTN1,KIF1A,TTLL9,CARMIL3,ADGRB1,BCHE,BCL2L2,NRP2,BID,GPR146,SYNJ1,CDK5R2,CA12,DDR1,CACNB2,CACNG1,CAMK2A,CAST,CH25H,CARS,CCKBR,METTL6,USP2,RGN,CD86,SCARB1,ENTPD2,MYOM2,CDK11B,CDC25B,KCNAB3,DCLK1,LRRFIP1,SYNPR,CHRNA4,RAB3C,CHRNB2,DLGAP3,NRXN3,CCDC151,CNN3,CNR1,FAM149A,COL11A2,NRG2,IGDCC3,NECTIN3,PNKD,CLOCK,CREM,NCOR1,ABCG1,LRRC3B,VCAN,RASGEF1C,DZIP3,SDC3,KATNAL2,EARS2,TM9SF4,DAPK1,DBT,DCC,DCT,FBXO25,PLPPR4,SGSM2,ARNT2,DLG2,NR1D2,CDON,DRD1,DRP2,FAM78B,EBF1,EDNRA,FRY,EFNA2,KCTD3,EIF4G1,ELAVL2,EML1,OLIG2,RCAN2,EPHB1,KCNMB2,IGSF6,DUSP27,F8,TOMM40L,FECH,SPSB4,FGF14,FGFR1,MEX3B,AGAP2,AGAP3,NOP56,TRIM16,CELF1,TMEM151A,DOT1L,STAG2,GABBR1,ILDR2,ARPP21,GALR1,NCKAP1,GAP43,HIGD1B,ACSS1,STARD10,GBX2,GCNT2,MSTN,PCDH17,LYVE1,GLDC,RAB30,ZNF638,DCLK2,RAB40B,GNG3,ADGRA3,LILRB4,GPD2,GPM6B,GRK4,GRIK3,GRM1,SOX21,PSIP1,GUCY1A2,HLF,HMX1,HNMT,CPT1C,HSD17B1,HSPA1L,HTR2A,IDH3B,IGF1,RBPJ,RIPPLY2,ITGA7,JAK2,KCNA4,KCND3,CLVS2,KCNJ10,KCNMA1,KCNN3,KCNQ3,IPO5,LAMA2,LRRC4B,LSS,MAPT,MARK1,AQP11,AFDN,MOV10,MYH6,MYH7,RCOR2,IDNK,SLCO1C1,NRCAM,OPHN1,CLDN11,P2RY1,PAH,PAX6,PCDH8,PCSK1,PDCD2,PDE1A,PDE3A,PDYN,GPR85,PFKFB2,CDK14,NLGN3,ANLN,A2ML1,ST8SIA5,SLC25A23,ZNF426,PRRX1,SDK2,PILRA,PPP2R5E,PRKAB2,PRKACB,PKN2,MAPK3,MAPK4,MAPK8,PRODH,PTCH1,ELOVL2,PYGM,RIPOR1,PLEKHB2,FAM184A,NWD1,RET,RFX2,RFX4,RFX5,RGS3,CYB561D1,CCDC25,RIMKLA,KCNIP1,RYR1,CCDC112,SCN2B,SCN3A,SCN4B,SCN7A,CASC3,SGK1,SH3BGR,SH3BP2,ITSN1,AMBRA1,ST8SIA1,ABLIM3,SLC4A3,EPN2,SLC6A9,KDM4D,SLC8A1,SMARCA4,MAST1,RCOR3,RIMS1,SNAP25,SNCB,KIF13A,UNC80,SOX2,SPATA7,ZCCHC24,CAND2,MYCBP2,UNC5B,ZNF423,ZBTB43,NFASC,EPB41L3,APOM,STX1A,STXBP1,GSE1,FAM168A,MLC1,SYN1,SYN2,SYP,TAC1,ANKRD12,AGTPBP1,TBL1X,TMEM136,TBX15,CLASP1,TMEM121,SPX,ARL10,THRA,TK2,KCTD2,TNR,RBFOX2,TPM1,TPM2,TPM4,WBP2,TRPC3,SSBP2,TUB,TUBB2A,UBTF,FAM181B,SLC26A10,SPHK2,SPIRE1,SMARCAD1,DNALI1,URM1,NAV2,KCNAB1,PDSS2,HRASLS,KAT6A,HNRNPA3,VANGL2,PRRT4" Drug ctd:D019287 Zinc Sulfate CTD 1.12E-07 5.50E-03 4.60E-06 5.23E-05 170 741 "VWA5B2,C3orf14,MTUS1,ALAD,MARCH4,OGT,APBB1,CADPS,STK33,CHRD,KIF1A,CALM1,CH25H,RGN,AIFM1,SYNGR3,MAGI1,GPR37L1,CHGA,CHGB,NGEF,LY86,RAB26,CNN3,CNTFR,CP,ABCG1,CS,CSF1,FEZ1,SIPA1L1,CHD5,RIMS2,ZSCAN23,DCAF8,MYEF2,MAGI2,DLG2,NR1D2,CDON,DRD1,ABCC9,EDNRB,EEF1A2,SEMA3D,SIDT2,FAM13A,EGFR,MBNL2,APC2,TUBB4A,RACK1,KAT8,FGF1,FOXO3,FLT1,ATP2C1,ERGIC3,PNMA2,TBR1,DOT1L,MEGF11,IQGAP2,GDF1,GGT7,GHR,PPARGC1A,BRD8,GLUL,GNAS,NR3C1,HBA1,TOX2,HMGCR,HSPA1L,HSP90AA1,HTR5A,IGF1,IL6ST,KCNJ5,KIF5C,KLRC3,AFDN,MOG,SESN3,SCG3,TAGLN3,MTTP,MYH7,NCF2,NEFM,NELL2,SLCO1C1,NKX2-2,NODAL,NPTX1,PCBP3,SLC11A2,NRCAM,P2RX7,PALM,CNTN3,PCSK2,PDE4A,PDE4B,PENK,CYTL1,PFKFB2,PFKFB3,NECAB2,PPARA,PPM1B,PKIA,MAPK3,MAPK7,MAPK8,PROX1,PRPSAP2,SNRK,PLPPR1,PXK,PTPRD,PTPRN,RIPOR1,RASGRF1,ZDHHC14,RGS4,RNH1,ROBO1,ROBO2,RPS6KA2,EMID1,RXRA,FNIP1,SMPD3,TRIM46,MRAS,SCG5,CNKSR2,LRRC55,SNAP25,UNC5B,TROVE2,SEPT8,SYT1,SYT4,KAZN,MTCL1,CNTN2,TBL1X,SATB2,DICER1,TLL2,RIMBP2,IL34,TPM4,CADM1,UCHL1,VIPR2,SLC13A3,KCNK12,SLC26A10,SPIRE1,INTS3,SLC30A4,SCG2,WIPF2,WNK2,SPATA13,JPH3" Drug 5940_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.12E-07 5.50E-03 4.60E-06 5.23E-05 56 178 "ABAT,ABHD6,ADRB2,AP2A2,NME5,ARNTL,MARCH3,BRINP2,ST3GAL5,HIP1R,ABCG1,PDE4DIP,CTH,NOS1AP,DNAJC6,C2CD2L,PLPPR4,EFNA3,TBC1D16,TAOK3,BAIAP2,DPYSL4,NBEA,FYN,GLS,STON1,SCIN,DIPK1A,ITGA7,KIF5C,MAP2,MAPT,PCDH9,ENPP2,SERPINI1,PRPH,PTCH1,RGS4,RPS6KA2,SH3GL3,KDM4B,TNIK,BEX1,ARHGAP26,ELOVL4,RGL1,SYT11,VAMP1,ARC,SYT1,ARHGEF12,RUNDC3B,SSBP2,DNAJC12,TRIM9,PLSCR4" Drug CID000003868 "pyrrolidine-2,4-dicarboxylate" Stitch 1.17E-07 5.71E-03 4.76E-06 5.42E-05 27 61 "ADORA2A,BCS1L,SLC32A1,GLUL,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,MAP4,OMG,PRPH,SLC1A2,SLC1A3,SLC6A1,SLC6A11,ABCC8,SLC17A7,SLC17A6" Drug CID000105153 rubidium Stitch 1.17E-07 5.71E-03 4.76E-06 5.42E-05 27 61 "SLC12A5,AGT,ATP1A2,ATP1A3,DDR1,SLC5A11,SLC12A6,GYG1,KCNA4,KCNB1,KCNC1,KCND2,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNMA1,AFDN,NBL1,SLC11A2,P2RX7,SLC12A2,SLC12A4,SLC14A1,WNK1" Drug 4463_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-07 5.72E-03 4.77E-06 5.42E-05 58 187 "ADGRF5,ANK1,APAF1,ASPH,ZBTB10,ATM,CACNA2D2,SRSF11,NMT2,ABCG2,CNR1,SLC4A7,PUM1,EDRF1,SEC14L5,NR1D2,DSCAM,DTNB,ETV1,TESK2,FOXG1,OGA,GAB1,ERAP1,DISC1,GFER,RND1,STON1,LPAR4,GRM2,GSTM5,IL6ST,LAMA2,MAP2,MMP16,NUMA1,OPCML,PDE4B,SERPINI1,PRKAB2,MAPK7,MAPK8,MASP1,MARCH1,ARID4A,RET,ATXN1,CNKSR2,SLC8A2,ZNF334,ARHGAP26,PLCB1,KIAA1107,PCDHGA10,TK2,SF1,WNK1,PLSCR4" Drug CID005486547 YM90K Stitch 1.19E-07 5.85E-03 4.77E-06 5.43E-05 15 23 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,CABIN1" Drug 6873_UP "H-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ACTN1,SLC12A5,NLGN4X,SEMA4G,ARNTL,ALDH7A1,BCHE,HIP1R,CBFA2T2,CRLF1,SOCS6,LHX2,NRXN3,ARMC8,CSF1,RIMS2,ST18,PYGO1,GIT2,RUSC2,MAGI2,SMG7,PLPPR4,CNNM1,CELSR3,MRNIP,F3,AFF2,DISC1,GLYR1,NCKAP1L,ATXN2L,SHISAL1,KCNH2,KCNMA1,KCNQ3,VWA5A,NF1,NOVA1,PDGFRA,PFKFB2,DUSP26,PRKAR1B,MAPK3,ARHGEF10L,KCNIP1,NTNG1,PEX26,FAM214B,RIMS1,VAMP1,PLCB1,TACR1,KIAA1107,CDK20,TRH,VGF,ZNF74,SCG2,GAN" Drug 3971_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "NDRG2,LTBP4,AMPD3,KCNAB2,FAM131A,PPP4R4,MARK4,BCL2L2,MTMR2,CA12,CAMK2B,SLC16A4,CDC42,DNAJB5,CPS1,SH2B1,CSF1,DZIP3,DOCK4,DCAF8,MAML1,MFAP3L,DUSP9,ZNF589,OGA,GAD1,TXNL4A,GPR37,GRIK5,KCNF1,KCNH2,KCNMA1,KCNN2,VWA5A,AFF1,ADAM22,ZNF862,NF1,CNOT4,NPTX1,CLDN11,MINDY2,PRKAR1B,RAD52,TCP11L1,BCAN,WDTC1,PEG10,TROVE2,PLCB1,PSD3,ZNF34,TK2,HIRA,FAM155A,WIPF1,KCNK12,SYNC,MVB12B,SENP7" Drug 5740_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "DPF1,SPARCL1,APBB2,GAS7,AQP4,ADGRB2,BAIAP3,PLEKHB1,STOML1,RAB26,CNR1,RIPOR2,FBXL5,SRGAP3,AK5,ST8SIA3,RGS17,EN2,RASGRP2,PTK2B,KIAA1109,FOXG1,FLT1,TRMO,ZNF44,GATM,LYVE1,COPS8,GPM6A,ATF7,EML4,GRIK5,GRIN1,ATXN2L,LSS,MGAT3,TAGLN3,NPPA,NRCAM,OPCML,SPATA6,CEP41,ZSCAN2,RGS4,EMID1,DOCK10,PPP4R3A,PKNOX2,SOX15,LHPP,SMG6,SYNE1,THRA,TLR4,PIK3R5,AMACR,LMF1,ZBTB14,ZIC3,ZNF711" Drug 6824_UP Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ASIC1,ADORA1,APLP1,AQP4,RASL11B,DDX3Y,ATP2A2,SCAPER,GYG2,CACNG1,CALB1,RCBTB2,FADS2,SULT4A1,WHRN,CSF1,VCAN,PDE4DIP,DBT,RUSC2,ELAVL3,DMTN,FGF1,PDLIM5,GAD1,SIGLEC8,ATF7,GPER1,GRIK5,GRM1,ICA1,KCNMA1,KCNN2,KIT,MX1,NTRK3,PDE4D,ZSCAN2,ZFHX4,RYR1,ST6GAL1,BCAN,CXXC4,SNCA,FAIM2,WDTC1,ZCCHC24,SPTB,MCF2L2,PHLDB1,AJAP1,SYT11,POPDC3,ATP11A,TBCEL,RPGRIP1L,CRTC1,DICER1,FLRT2,WIPF1" Drug 4484_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "AQP4,BMP7,FUBP1,BAIAP3,CFAP410,CDC42,CDH8,TAOK2,RAB33A,STOML1,HOMER3,PCYT1B,HAPLN1,ARHGEF10,MICAL2,PDE4DIP,CTNND2,CTIF,SPOCK3,EXOG,TRAPPC9,DNM2,DOCK2,DTNA,DYRK1A,NCALD,ETV1,PIPOX,ACTL6B,GAB1,ATP8A2,GNG3,LILRB4,ITGA7,KCNH2,SLCO1C1,NPY,OPRL1,PIK3CD,PRRX1,TNPO2,PPP2R2B,PPP2R5C,PRKAR1B,KCNIP1,FBXO11,SLA,SLC1A7,SLC6A11,SLC11A1,SEMA4A,BEX4,PIK3R5,TPM3,VAV1,WIPF1,SLC13A3,SPHK2,KCNAB1,AP3B2" Drug 2491_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "MTUS1,BEGAIN,CNTNAP1,ARHGDIG,ATP2B2,BMP7,CDK5R1,CACNA1G,BTRC,CBFA2T2,CDC42,CDO1,CACNA2D2,TPP1,RAB26,NCOR2,CRYM,CSNK1E,PPP1R16B,DCAF4,KIAA0513,DSCAM,EDNRA,VPS13B,RASGRP2,STX2,CDKL3,AGAP2,CAMKK2,GAD2,HPGDS,GLYR1,GPR22,GRIK5,IL12A,MAPT,AFDN,MMP17,MPP2,ADAM22,MSR1,MX1,NOVA2,CCSER2,PLCL1,GDPD2,MARCH1,PID1,RGS10,SLC1A7,SMTN,DOP1A,SP4,ZC3H13,MAPK8IP3,CUX2,PSD3,RBFOX2,FAM155A,SLC13A3" Drug 2705_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ACTN2,ADORA1,NR0B1,BIN1,OGT,ANK3,DNAH17,PTCH2,DDX3Y,MPDZ,KSR1,CCK,CHRNB2,NRXN3,COL4A5,SIPA1L1,CNTNAP2,PYGO1,DAPK3,DLG3,SORBS3,RASGRP2,EFS,OLFM1,PRELID3A,CSPG5,SIGLEC8,SEPT9,GLS,PRUNE2,RAPGEF1,KCNF1,KCNMA1,MAPT,MBNL1,AFDN,MPP2,MYO7A,NPY,NOVA2,NPPA,PGAM2,PLP1,PPP2R2B,GRAMD1C,GDPD2,GAL3ST4,SYNDIG1,TRIM46,SORCS3,SNAP25,SCN3B,SOX2,PLCB1,PCDHA5,CHST8,MKRN3,SPHK2,SLC17A6,KAT6A" Drug 1517_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ADORA2A,ADRA1D,KIAA1324,ADGRF5,SYT13,APOC1,MARK4,SYNJ1,CACNA1I,CFAP410,CAMK2B,RHBDL1,CACNA2D2,SOCS6,TAOK2,CSF1,CTH,CTIF,ZNF804A,MAGI2,CDON,EFNB3,HSD17B14,KCNMB2,F5,CAMSAP1,HPCAL4,PRELID3A,TMEM8B,DISC1,GATM,MSL3,GRB10,GSN,PTGDR2,HNMT,TJAP1,INPP1,KCNK2,VWA5A,MAP2,MX1,PIK3CD,SLC25A23,PPP5C,ELOVL2,ZSCAN2,RAD52,RAVER2,WLS,SYBU,FAM214B,SLC11A1,ZNF423,INKA2,SEMA4A,SZT2,CDK20,XRCC4,PARP11" Drug 5071_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ASIC1,NME5,BIN1,EPB41L5,SLC4A4,SYNJ1,BTRC,KYAT1,CDC42,FOXN3,SOCS6,TAOK2,QKI,CPS1,CSF1,CNTNAP2,ZNF804A,RUSC2,SPOCK3,KBTBD11,EXOG,FEM1B,MBNL2,IRAK4,ETV1,RRAGB,ZNF589,IQCG,C1QL1,KCNMB4,GPM6B,CNTRL,SHISAL1,IL11RA,KIF5C,LIG4,TM6SF1,ZNF862,NF1,ODF2,PAK3,PDE1C,PPARA,WDR25,PTCH1,GAL3ST4,TTLL7,TRAPPC13,ASAP3,DZIP1,KDM4D,ZNF415,SPTAN1,TK2,CABIN1,SSBP2,OSBP2,TFIP11,NAV3,FZD3" Drug 6039_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "SYN3,C1QTNF1,AMPH,BIN1,GAS7,SLC4A4,CACNA1I,INA,CDH2,CLCN4,HOMER3,CNN3,PICK1,ABI3BP,CHD5,SDC3,SPOCK3,TRAPPC9,EGR3,EIF1,TUBB4A,KHDRBS3,FYB1,GPR162,ADAM28,PCDH17,RUNDC3A,GRIK2,CACFD1,ATXN2L,KCND3,KCNJ4,KCNN1,MBP,MDFI,ADAM22,NEFH,NOVA2,PALM,NECAB2,LRRN3,MASP1,PTPRB,RGS12,MYH14,SYNDIG1,KCNIP2,SCN2B,SORCS3,SNAP25,SNCA,WDTC1,ZCCHC24,CAND2,UNC5B,MAPK8IP3,HEY2,LAT2,CA10,JPH3" Drug 6158_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ASPHD1,ADORA1,ALK,BCAS1,CDK10,CACNA1I,MYRF,HAP1,CHRNA4,NRG2,CHD5,FAM169A,CTIF,DSCAM,E2F5,ST8SIA3,SORBS3,SRPK3,HSD17B14,RCAN2,ERBB4,RASL12,OLFM1,FOXG1,AGAP2,TACC2,TBR1,GAB1,GAD1,GFER,RUNDC3A,RAPGEF1,GRIA4,GRIN1,GRM1,GUCY1B1,PTGDR2,AFDN,MYO7A,MYT1,NELL2,PNMA3,SEPT4,RASGRF1,KHDRBS2,RPS20,ASIC4,FERMT1,SLC1A3,EPN2,SLCO1A2,INKA2,PHLDB1,WWC1,ACSL6,TCF4,DOCK9,SLC19A3,BEST1,SLC17A7" Drug 2726_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ASPHD1,ACTN2,BEGAIN,SLC4A4,BCL2L2,SGCE,CACNA1I,CFAP410,RHBDL1,CDO1,ZFYVE9,CNR1,AKAP6,TCEAL2,CREM,AATK,CSF1,BRINP1,SPOCK3,FGFR1,FHL1,FOXG1,PRELID3A,INPP5K,PCDH17,GPM6B,LILRA2,GUCY1A1,HTR2A,ICA1,TJAP1,KCNH2,MDM4,MGAT3,BCO1,CNOT4,NPPA,PLCD1,CEP41,PKIA,CNNM2,WDR25,PBRM1,PLPPR3,SYNDIG1,FERMT1,CPEB3,NTNG1,SYBU,PKNOX2,SHANK2,TMCC1,SOX15,SSTR2,INKA2,TCF4,PCDHGA10,FLRT1,LMF1,PRDM10" Drug 3986_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "RALGAPA1,LTBP4,DOC2A,BIN1,SEMA7A,APAF1,PPP4R4,DDX3Y,CADM3,ADAM23,CACNA2D1,SCARB1,CHRNB2,SLC22A6,KIAA1549L,AKAP5,IFFO1,TBC1D5,SMG7,EDIL3,HIPK3,PLXNC1,ING4,TNK2,EPHA5,ETV1,HPCAL4,OGA,STON1,GRM2,IL12A,KCNF1,KCNN2,MARK1,ADAM22,NRCAM,CLDN11,PGAM2,PNMA3,PRKAR1B,PTPRD,PTPRN2,ACSS3,BEND5,GSTCD,CSRNP3,PREX2,SLC14A1,OGDHL,SMARCD3,SOX15,ZHX3,HECW1,CRTC1,SLC44A1,TRPC1,HIRA,UCHL1,VGF,VIPR2" Drug 2740_UP Pyrithyldione [77-04-3]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "TRMT9B,DNAH17,ASPH,B3GALT2,AZGP1,RGS9,KSR1,CHRNA4,PLAA,HAPLN1,NCOR2,RGS6,PDE4DIP,BRINP1,MFAP3L,CDON,ST8SIA3,MBNL2,AASS,DLC1,FHL1,ZNF44,SEPT9,GPD1,GRK4,GRIK2,GRM1,GRM8,HPSE2,HTR5A,KCNC1,KCND3,KCNMA1,MAPT,MGAT3,AFDN,MYO6,NCAM1,PMP2,PPP1R1A,PTPRB,SCN2B,MRAS,CCDC92,NLGN1,KANSL3,SLC6A9,ZNF415,SOX2,SYT5,ROBO3,TAL1,TMOD1,LILRA4,TRIO,TRO,LMF1,XRCC4,SLC17A7,FAM13C" Drug 6200_DN "estradiol, USP; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ABHD6,ADD2,MTUS1,BCAR3,ALDH4A1,SCAPER,CAPN3,INA,TAOK2,PLAA,CNTN1,AKAP7,SLC4A7,CREM,ENTPD4,SH2B1,CRY2,SEC14L5,GSDME,SGSM2,SIDT2,CELSR3,FAM13A,C1orf61,GAA,GAB1,SRCAP,GNG4,CACFD1,SOX21,TJAP1,IL6ST,IL11RA,SMAD1,NF1,NUMA1,OGG1,SERPINE2,STRN3,MAPK8,BCAS3,PEX5,GALNT10,URGCP,LIMS2,SLC6A8,DDN,CAMSAP2,KIAA1107,CUX2,TCF7,TMOD1,RBFOX2,ZKSCAN5,LAT2,WNK1,MAP3K12,EVI5,GDPD5,NLRP3" Drug 3070_UP Metyrapone [54-36-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "NR0B1,ALK,TRMT9B,APBB2,PPP4R4,MYOM1,CACNG1,HIP1R,INA,ZFYVE9,CLCN4,C2CD2,CREM,ABCG1,PDE4DIP,ARHGEF4,KIAA0513,SPOCK2,RUSC2,DYRK1A,EFNA3,CEND1,DLC1,OLFM1,FGFR1,BAIAP2,C1orf61,GABRG2,ALDH1L1,GNG4,GPD1,GPM6B,ATF7,GRM8,GUCY1A2,KLF12,TJAP1,MAP4,AFDN,MOBP,ADAM22,NCAM1,SLCO1C1,NPPA,NPTX2,NTRK3,PFKFB4,ST8SIA5,PTPRZ1,RASA3,ST6GAL1,KANSL3,DOK5,SEPT8,STX1A,SYN2,PCDHGB6,TNS2,SPX,NT5M" Drug 4497_DN Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "NME5,APBB1,APOC1,CDK5R1,SYNJ1,SYNJ2,SCAPER,MYRF,IL33,BTRC,SCARB1,RAB28,CLCN4,DNAJB5,LY86,AKAP7,WHRN,SLC4A7,VCAN,GIT2,SIRPA,SPATA2,CNIH3,MFAP3L,DTNA,EGFR,SORBS3,TNK2,PLEKHO1,EPB41L2,SPEG,ATP8A1,KIAA1109,FGFR1,CGREF1,MSL3,GPER1,GUCY1B1,LIG4,LSS,NDUFA5,NFYA,PC,MINDY2,PTHLH,RGS7,PAQR6,SLC20A2,SPTB,NXT2,ASTN2,FBXW11,GPR161,TK2,WNT7A,ZNF711,SEMA3B,FZD3,PHTF2,DPF3" Drug 1713_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "NDRG2,ADD3,APBA2,APBB2,CDK10,INA,ENTPD6,NEURL1,RCBTB2,ZFYVE9,PICK1,CSF1R,OSBPL3,DOCK4,GIT2,SMG7,DNM2,FEM1B,ABI2,BSCL2,PLEKHO1,VPS26C,EZH1,KIAA1109,GFER,PRRC2B,LILRA2,NF1,NFYA,NTRK3,NUCB2,CLDN11,CCSER2,ZFYVE21,NLE1,SMOX,MBOAT7,MINDY2,CCDC40,TCP11L1,PAQR6,SAFB,SATB1,ATXN1,CCDC88A,SLC15A2,ELMO2,INTS9,KDM4C,ARHGEF9,NACC2,KAT6B,TNNT1,TNS1,PIK3R5,PLPPR2,XRCC4,HPS4,NLRP3,RNF170" Drug 6364_UP CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "DPF1,ADORA1,NLGN4X,NME5,KIAA1324,AMPD3,APBA2,ARRB1,PDE8B,DNAH17,ATP1A2,SLC4A4,GYG2,CD38,CLCN4,STOML1,FAM149A,AATK,CSF1,TENM4,CSF1R,RGS6,MICAL2,RIMS2,SEC14L5,DTNB,USH1C,SEMA3D,SPEG,C1orf61,NSG1,SEPT9,GLYR1,KCNMB4,GNAO1,GPM6A,GRM2,KLF12,KCNMA1,KIFC3,FXYD6,TREM2,SNTG1,CDK14,PIK3CD,PLCB2,LRP12,ACSM5,ZFHX4,FNDC3A,SLC11A1,SNCA,IZUMO4,MCF2L2,RGL1,TCF4,CHST5,LAT2,SLC13A3,FAM13C" Drug 3194_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "NDRG2,PRX,PPP4R4,ARHGDIG,ATP2B2,ADAM23,AZGP1,CFAP410,KALRN,RUNX1T1,CD86,CDC42,B4GALT6,RCHY1,IFFO1,CLIP3,RGS6,IPCEF1,SNPH,PHYHIP,CTIF,SHANK1,HIPK3,ING4,TLR7,OLFM1,C1orf61,AFF2,KHDRBS3,DLL3,SEPT9,RUNDC3A,GNAO1,GRIK1,KLF12,KIFC3,VWA5A,CD200,MYT1,NPPA,OMG,PLTP,PSD,RALGDS,TRIM68,RGS4,SLA,PKNOX2,LMO3,INKA2,SYT5,POPDC3,TACR1,KIAA1107,CUX2,SEZ6L,TRH,ZIC3,MKRN3,SEMA3B" Drug 3706_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ADRA1D,AGT,NME5,LTBP4,BEGAIN,PPP4R4,ASPH,ZSCAN18,RASL11B,ALDH4A1,ATP2B3,NRP2,BMP7,SYNJ1,C5,CFAP410,USP2,CHM,CNTFR,CREM,CYBB,SPOCK2,ARNT2,HS3ST2,ECM2,EDIL3,EDN1,EGFR,EPHB1,DLC1,FGFR1,GAP43,GDF9,GNG3,GPR19,LPAR4,GRM2,SOX21,KCNH2,LMO1,LSS,MEF2C,MYBPC1,CLDN11,CDK18,PDGFRA,POU3F2,ELOVL2,PTPRD,RFX2,SYNDIG1,SLC1A2,RPH3A,SLC1A7,ZNF334,CRTC1,TRO,ZMYND8,SPHK2,MVB12B" Drug 4526_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "SLC12A5,AGT,PPFIA4,PPP4R4,BRINP2,ADAM23,NRP2,KSR1,SCAPER,CALB2,CAPN3,USP2,NEURL1,CHI3L2,CLCN4,CABP1,NRG2,CNTNAP2,NOS1AP,DTNA,ELN,FGF1,FGFR1,FLT1,DCTN2,PDLIM5,HBS1L,GAP43,HPGDS,LILRA2,GPR19,GRM8,KLF12,ICA1,KIF5C,LIFR,LSS,MN1,ADAM22,MSR1,NEUROD1,NRCAM,OXTR,SNTG1,PDGFRA,PTPRH,CCDC40,KHDRBS2,RGR,SCN3A,RBM34,ACSBG1,SYT11,ZEB1,THRA,TLR4,TMOD1,TRPC1,VIPR2,KCNK12" Drug 3099_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ABHD6,MTUS1,BIN1,SEMA7A,ARSE,ALDH4A1,SLC4A4,BMP7,CFAP410,INA,CBFA2T2,AKAP6,NCOR2,CRYM,CNTNAP2,DZIP3,DCT,EDIL3,SORBS3,OLIG2,RASGRP2,STX2,NCALD,TUBB4A,DLC1,GAD2,SIGLEC8,ALDH1L1,HNMT,ITIH2,KIF5C,MAP4,MGAT3,SCAMP5,ADAM22,MYBPC1,MYT1,SEPT4,FSD1,CEP41,PRKAR1B,MASP1,FAM120C,TMEM255A,RAD52,FAT4,MYH14,RORB,TCP11L1,ASAP3,ABLIM3,SLC11A1,SLCO1A2,HECW1,NPAS3,TRPC1,XRCC4,MAP3K12,STMN4,KCNAB1" Drug 6667_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "ACHE,PPFIA4,PPP4R4,ARHGDIG,CCDC181,ATP6V0A1,ADGRB2,BTRC,SLC24A2,HOMER3,CNTFR,AKAP6,CRMP1,PDE4DIP,PHF14,SPOCK2,MFAP3L,DTNA,DTNB,EDN3,PLEKHA1,EPHB1,NCALD,ETV1,REEP2,FGF1,FGF12,SORBS1,GAD2,ATP8A2,GPER1,CACFD1,HTR2A,ICA1,KCNC1,KCND3,KCNMA1,LIG4,KITLG,P2RY13,PCDH9,PDE3B,PDE4B,GPR85,LRRN3,PRPH,ZSCAN2,ENOX1,ZMAT4,DOCK10,SNCA,ZHX3,NFASC,NACAD,COBL,DAAM2,CHST5,TRO,ZNF74,SPHK2" Drug 6832_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-07 5.85E-03 4.77E-06 5.43E-05 60 196 "TRMT9B,KCNAB2,AQP4,PPP4R4,ASCL1,ALDH7A1,CACNA1G,CA12,BRSK2,ADGRG1,FAM149A,COL9A3,RCHY1,GREB1,HDAC9,GIT2,DCT,MBNL2,PLXNC1,IGSF6,EXTL1,FABP7,PDLIM5,SEPT9,POLL,ATF7,GRM7,PTGDR2,KCND1,MAN2A2,MDM4,MID1,ZNF862,MYT1,TREM2,SERPINI1,PTAFR,ZSCAN2,CEP97,ZMAT4,MYH14,TCP11L1,SEMA6D,SCN8A,SH3BP2,RPH3A,SLC1A7,SLC2A5,PEX26,FAM214B,SHANK2,ZCCHC24,IZUMO4,ARHGAP26,ATP11A,TNS1,AMACR,VIPR2,NT5M,NUP214" Drug CID000002818 clozapine Stitch 1.22E-07 5.98E-03 4.88E-06 5.55E-05 77 274 "SERPINA3,ADAR,ADRA1D,ADRA1B,ADRB2,OSBPL8,CALM1,AIFM1,CHGA,CHRM1,CHRNA4,CHRNB2,NRG2,CALY,DLG4,DRD1,DTNA,DTNB,OLIG2,ERBB4,EFS,RASL12,NRG3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,DISC1,NTNG2,GNAL,MCHR1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM2,GRM3,GRM5,HRH3,HTR2A,HTR5A,KCND2,NPY,PDE4B,GPR85,PENK,PPP3CA,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,PRODH,SLC1A2,SLC1A3,NPAS3,SYT5,CABIN1,TRIO,NTSR2,SCG2,SLC17A7,SLC17A6,SSPN" Drug 7084_UP MS-275; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.27E-07 6.24E-03 5.08E-06 5.78E-05 57 183 "ABHD6,ADGRF5,ARNTL,ATP2B1,ST3GAL5,IL33,CLU,CREB5,ABCG1,VCAN,CNTNAP2,DOCK4,PLPPR4,ARNT2,EDNRA,RGS17,ATP8A1,FGF1,FGF13,FYB1,GLS,GRB10,GUCY1B1,BACH2,KIF5C,MAP2,MEF2C,MMP16,TAGLN3,PDE4B,PDGFRA,ENPP2,PIK3CD,RETREG1,PMP22,PTHLH,RGS4,RGS7,ATXN1,ST6GAL1,SYBU,TNIK,BEX1,THSD1,CEP68,RGL1,SYT11,SYT1,COBL,ARHGEF12,TGFBR3,DNAJC12,XRCC4,TRIM9,SEMA3B,NAV3,PLSCR4" Drug 4711_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-07 6.41E-03 5.21E-06 5.93E-05 59 192 "NME5,NR0B1,ALK,AMPD2,AMPD3,NRP2,CFLAR,CACNA1A,SEPT7,STOML1,CREM,FEZ1,ATRNL1,SEC14L5,GIT2,GNE,DTNA,EGFR,EGR3,ING4,ENO2,ANKMY1,FHL1,DCTN2,FAM49B,ATP2C1,GRM7,HLF,IL6ST,INPP1,ITGA7,VWA5A,NEUROD2,RETREG1,MTRF1L,PPP5C,RELN,PTX3,RAD52,ROM1,TCP11L1,SYBU,SLC2A5,SLC9A5,SMARCD3,KDM4B,IZUMO4,COLGALT2,AJAP1,VAMP1,CHST8,UBE3A,ZIC3,WNK1,PRDM2,NT5M,SEMA3B,SSPN,AP3B2" Drug 4269_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.31E-07 6.41E-03 5.21E-06 5.93E-05 59 192 "MTUS1,ASPH,ADAM15,CFLAR,SYNJ2,SCAPER,SPAG9,KRIT1,CDC27,SRSF11,NMT2,QKI,TBC1D5,DBT,ZBTB24,RHOBTB1,IRAK4,VPS26C,EFEMP1,GAD1,INPP5K,HNMT,AGFG1,SHISAL1,IL6ST,MAP4,MIA2,NUMA1,OGG1,OPA1,PDE1C,PIK3R1,SNX10,STRN3,PRKAB2,GON4L,PTN,RAD51D,SLC25A36,KIRREL1,SBF1,SEC14L1,TNIK,PBLD,MAPK8IP3,PLCB1,KIAA1107,EHBP1,PSD3,DICER1,BHLHB9,NSD2,SF1,WNK1,PRDM2,EVI5,KCNAB1,UBE3B,FXR1" Drug 3236_UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.31E-07 6.41E-03 5.21E-06 5.93E-05 59 192 "NDRG2,SPARCL1,CDK13,ATP1A3,NRP2,CA4,CLGN,ARHGEF10,VCAN,ARHGEF4,RIMS3,MFAP3L,NTM,EDNRA,EFNB3,EGFR,AASS,TNK2,ARMCX1,FGFR1,IQCG,SORBS1,HBS1L,ALDH1L1,GLYR1,ADAMTS13,HMGCR,VWA5A,LSS,SMAD1,MAN2A2,MATN3,MMP16,GIT1,ADAM22,TAGLN3,ZNF862,NNAT,PCBP3,NUMA1,LRP12,PTAFR,TTLL7,CCDC102B,RPS6KA2,SBF1,CPEB3,SHANK2,ZCCHC24,ARHGAP26,SPTB,TRIM2,PSD3,TPM2,CHST5,FAM155A,FLRT2,NT5M,SENP7" Drug CID003931705 L000369 Stitch 1.37E-07 6.69E-03 5.43E-06 6.18E-05 21 41 "ADORA1,CLTC,DCT,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,P2RY1,PENK,PRKCG,SALL1,TRPC1" Drug CID000001066 quinolinic acid Stitch 1.39E-07 6.79E-03 5.51E-06 6.27E-05 56 179 "ACHE,ADORA2A,APAF1,DDO,PDXK,CALB1,CALB2,CNR1,CNTFR,DYNC1I1,DRD1,ATN1,EN2,PPP1R1B,FGF1,B3GAT1,GAD1,GAD2,ARPP21,GFAP,GFRA1,PPARGC1A,TCERG1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PACSIN2,TNFAIP8L3,HMGCR,IL6ST,LIFR,MAOB,NPY,OGG1,PAH,PDYN,PENK,PACSIN1,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SST,ZFP91,PORCN,JPH3" Drug CID000000187 acetylcholine Stitch 1.40E-07 6.86E-03 5.52E-06 6.28E-05 95 361 "ACHE,ACLY,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,APOC1,APOC2,ATP1A2,ATP1A3,BCHE,CACNA1B,CACNA1E,CALM1,CCK,CD38,CHRM1,CHRNA4,CHRNB2,CNR1,SLC32A1,PLCXD3,SV2A,DMPK,DRD1,EDN1,EDN3,EDNRA,EDNRB,DMTN,CELF1,PNMA2,B3GAT1,GAD1,GAD2,GALR1,CRCP,GLRB,KCNMB4,GRIA1,PLCD4,GRIN2C,GRIN2D,HRH3,HNRNPK,KCNA2,KCNJ3,KCNJ4,KCNJ5,KCNMA1,NOS1,NPY,NOVA2,NPPA,OPRL1,PCMT1,PDYN,PENK,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,KLK6,RAB3A,RIMS1,SNAP25,PEG10,SST,STX1A,STXBP1,ABCC8,VPS13A,PLCB1,SYP,SYT1,TAC1,TAC3,ATP11A,TACR1,SLC44A1,ZFP91,TMPO,TRH,VIPR2,ZIC3" Drug ctd:D059808 Polyphenols CTD 1.42E-07 6.97E-03 5.52E-06 6.28E-05 114 455 "SERPINA3,SYN3,SLC12A5,ADRA1D,GAS7,AQP4,ARRB2,CADPS,ASPA,ATP1A3,HCN2,NRP2,BID,CD81,CDC25B,CDC42,NRXN3,CNGA3,CABP1,SLC25A27,HAPLN1,ABCG1,CRYM,PDE4DIP,ERC2,CX3CR1,NOS1AP,CYBB,RASSF2,DGKB,DBN1,CEP170,CD99L2,CDON,ABCC5,EDN1,TNK2,EPHA5,CDHR1,CEP78,OLFM1,FGR,HPCAL4,POMT1,ERAP1,SYT17,GATM,NEU3,PPARGC1A,GLS,GLUL,MCHR1,GPR26,GRIK1,GRIK5,GRIN1,NR3C1,HAS2,HNMT,HPCA,HSF2,IL12A,KCNA2,KCNA4,KCNQ3,KLC1,MAOB,MARK1,SCAMP5,CD200,MPP2,SCG3,DDX25,MYCN,SLCO1C1,NFE2L2,HCN1,NTRK3,OLR1,OXTR,PDE3B,PDPK1,PFKFB2,PFKFB3,PFKFB4,CAMKV,NECAB2,POU3F2,PTPA,PPP3CB,MAPK3,PRPH,PTCH1,RGS3,RGS7,TMLHE,TNFRSF19,ASIC4,SELL,PPP1R9A,SH3GL2,SIRT2,SHANK2,SEPT3,TACR1,TCF7,SIRT1,TPM3,ZFP37,KCNAB1,SLC17A6,FZD3,GJC2,NUP214" Drug 5596_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.43E-07 7.02E-03 5.52E-06 6.28E-05 58 188 "SYN3,AMT,APAF1,CDK13,DNAH17,CFLAR,LDLRAD4,CACNG1,CAMK2B,CBFA2T2,REPS2,ASIC3,ZFYVE9,CSF1R,VCAN,CNTNAP2,CTH,RASSF2,SGK2,HIPK3,MBNL2,PLXNC1,ING4,C3orf18,MTSS1L,EPHB1,EFS,CORO2B,TMEM8B,GLS,STON1,HAS2,TJAP1,KCNJ5,LMO2,MSR1,LYRM9,NCAM1,SLCO1C1,CNOT4,NTRK2,PENK,SERPINI1,MAPK8,PTN,RAVER2,TCP11L1,CPEB3,KDM4B,KDM4C,SPTB,ATP10B,ZEB1,TEX15,DNAH7,R3HDM1,LAT2,MVB12B" Drug ctd:D008942 Mitoxantrone CTD 1.43E-07 7.02E-03 5.52E-06 6.28E-05 71 247 "C3orf14,ANK2,KCNAB2,ZSCAN18,ATM,ATP1A2,BMP7,CACNA1G,MYOM2,CACNA2D2,CLU,ABCG2,MAGED1,RCHY1,VCAN,CTH,HDAC4,DAPK1,CHRDL1,DMD,ELAVL4,EN2,EPB41L2,ERBB2,EXTL2,FDFT1,FHL1,FOXF2,SORBS1,FYN,AHCYL1,MTHFD2,RND1,GLUL,NR3C1,GUCY1B1,ELOVL5,IDH3A,JAK2,KCNH2,LAMA2,MEST,MXI1,MYH6,MYH7,NEFH,PBX1,PDE4D,ABCB1,SCHIP1,IRX1,SYTL2,PTPRE,PYGM,RBBP8,LGR4,SCN2B,CASC3,FNDC3A,SEC31A,BTBD3,MYCBP2,SPP1,SATB2,TRIM2,ZMAT3,TNNT1,TPD52,TPM1,UCHL1,EVI5" Drug 4702_DN Flurandrenolide [1524-88-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "NDRG3,ADCY6,SEMA6A,PPFIA3,CDK13,MARK4,ATM,KIF1A,CFLAR,CAMK2G,ARHGAP33,CREM,LRIG1,GREB1,DCAF8,DAPK3,DBN1,JAKMIP2,RUSC2,PARD6A,RCAN1,EFNA3,SUGP2,MBNL2,EML1,HSD17B14,COQ7,ZNF589,PDLIM5,TPK1,ERAP1,DISC1,MSL3,POLL,GPD2,DHX35,KCNJ3,LMO2,MITF,LYRM9,NEUROD1,NF1,NFYA,NPTX1,RETREG1,PPP2R5C,GON4L,FBXW7,WLS,SBF1,FNDC3A,SLC15A2,BTBD7,KIF13A,THSD1,MAPK8IP3,RPGRIP1L,ZMYND8,VIPR2,GAN" Drug 1513_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADORA2A,ADRA1D,CNTNAP1,APOC1,CDK13,SLC4A4,SLC2A11,CACNA1I,ARHGEF1,ARHGAP33,CHRNB2,CNN3,SLC4A8,ATRNL1,TOM1,EFNB3,CELSR3,TNK2,ELN,REEP2,FHL1,ERAP1,DISC1,GLYR1,POLL,TDRKH,GRIK5,NR3C1,GSN,HLF,HSF2,ICA1,IL6ST,ITIH2,BCO1,ZNF862,NELL2,NOVA1,OMG,CLDN11,CDK18,PIK3CD,MAPK10,PRPH,PTHLH,RAB3A,MYH14,WLS,RASA3,EPN2,ELMO2,BTBD7,EMC1,SPART,STX1A,SYN2,PSD3,PIK3R5,WIPF1,SCG2" Drug 2667_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABAT,MTUS1,ALK,BEGAIN,PPP4R4,DNAH17,NRP2,BMP7,MTMR3,RUNX1T1,SCARB1,CHRNB2,RAB33A,STOML1,RAB26,DCAF4,DGKG,DBT,MAMLD1,HIPK3,MBNL2,ING4,RASGRP2,ZNF549,F5,FHL1,PDLIM5,GALC,INPP5K,ADAM28,GNAO1,LILRA2,ADAMTS8,LSS,MEF2C,AFDN,NF1,NINJ2,NUMA1,PDE1C,NLE1,PLEC,PTPRN2,TCP11L1,KCNIP2,SLC11A1,SLC14A1,SNAP25,EMC1,PEG10,ST5,DNMBP,TBCEL,TCF7L2,CHST5,ZKSCAN5,SH3GLB2,PRDM10,KCNAB1,PHTF2" Drug 6805_UP Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "FZD9,AGT,GAS7,SLC4A4,ALDH7A1,ADAM23,SCAPER,CACNA1I,CACNA1A,CACNG1,CAMK2B,INA,CD86,CLGN,ADGRG1,SULT4A1,FAM149A,WHRN,CPS1,VCAN,PDE4DIP,ELMO1,CDON,DRD1,ECM2,SGK2,KIAA1109,OLFM1,SORBS1,GAB1,ZNF44,GAD1,PCDH17,GNAL,GNAO1,GRM1,GRM7,ELOVL5,KCNMA1,MYH7,CDK14,PRKAR1B,MAPK10,PTAFR,PTX3,CRTAC1,MYH14,RASA3,FAM214B,CCDC88A,WDTC1,CAND2,PHLDB1,PLCB1,SZT2,TLL2,SEZ6L,TPM2,UCHL1,VIPR2" Drug 5761_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADD2,APBB1,CADM3,NRP2,CALB2,CAMK2B,RUNX1T1,NEURL1,CDH8,CDO1,LHX2,VAX2,HOMER3,WHRN,CRMP1,SEC14L5,SRGAP3,PLXNC1,RGS17,MTSS1L,NRN1,HPCAL4,NSG1,GABRA2,INPP5K,GNAL,ELOVL5,ICA1,SHISAL1,C2orf72,LAMA2,LMO2,MAOB,MBD1,MSR1,TAGLN3,NEUROD1,NPPA,NPTX1,OPCML,PDE4D,RETREG1,SEPT4,PRKCB,PROX1,MASP1,FAT4,CCDC102B,NEK11,FRMPD1,PPP4R3A,DMXL2,TEX15,SLC44A1,ICAM5,TRO,FLRT2,VLDLR,LAT2,SLC17A7" Drug 7239_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADORA1,AK2,C1QTNF3,APOC1,CDC14B,PRX,MARK4,ST3GAL5,CALB2,CAMK2B,CACNA2D2,ASIC3,EPS15L1,STOML1,AKAP7,CPS1,NCOR2,PDE4DIP,SDC3,EDRF1,RIPOR2,EFNA3,CEND1,NRN1,KIAA1109,ANKFY1,GAD2,ALDH1L1,GCNT2,SRCAP,GRM7,ELOVL5,HNMT,KPNA5,LIG4,KITLG,MITF,MSI1,ADAM22,NNAT,CNOT4,PDE3B,PRRX1,MAPK8,KCNIP1,SYBU,FAM214B,WDTC1,ZCCHC24,PHLDB1,JMJD6,ATP11A,TACR1,PCDHGA10,TEX15,TK2,PDIA2,MAP3K12,SSPN,SENP7" Drug 2826_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "RALGAPA1,NDRG2,ADD3,KIAA1324,NRP2,CFLAR,BAIAP3,CACNB2,CAMK2B,CAST,KYAT1,ARHGAP33,FOXN3,TAOK2,PICK1,SIPA1L1,CTNND2,EXOG,TOM1,DUSP9,SIDT2,OPTN,PLXNC1,NCALD,ZNF589,FGFR1,SCARA3,SORBS1,GAB1,GAD1,NEU3,RUNDC3A,GNG4,SPACA9,IPO5,MAOB,MITF,TAGLN3,MYO7A,PCDH9,PDE4D,PFKFB2,PTHLH,RAD52,ROM1,EMID1,SYNDIG1,KCNIP1,RASA3,SH3BP2,PREX2,ARHGEF40,WDTC1,ZCCHC24,TEX15,HEY1,TIMP4,FAM155A,MICAL1,ST7" Drug 4642_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "TRMT9B,APC,DDO,ASTN1,ATP2B2,CADM3,ADGRB2,CACNA1I,BAIAP3,LDLRAD4,BTRC,CAMK2B,GPR37L1,CHI3L2,ABCG2,CABP1,TCEAL2,NRG2,CSF1R,SGSM2,DTNA,DTNB,ST8SIA3,HEYL,ETV1,F5,FGFR3,AFF2,FAM49B,FYN,ZNF44,SIGLEC8,GLS,GRIK2,GRM1,GRM8,IL12A,MGAT3,NEUROD1,PRKAR1B,ELOVL2,PTPRB,KHDRBS2,RGR,RGS10,FOXRED2,SCN2B,FRMPD1,ASAP3,SLC1A7,SLC6A9,SOX2,EMC1,KDM4C,ADGRL3,THRA,CADM1,REEP1,NT5M,SEMA3B" Drug 3048_UP Propofol [2078-54-8]; Up 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ACHE,ANK2,APC,AQP4,RGS20,ATP2B2,CADM3,CFAP410,P2RX6,CDH10,LHX2,CNTFR,TCEAL2,SUSD5,PDE4DIP,SPOCK3,ARNT2,EDN3,CALCRL,RCAN2,CACNG2,BAIAP2,SEPT9,ZNF276,GRIK5,FAM107A,GPR45,HTR2A,SCIN,IL6ST,KCNK1,ADAM11,MYCN,NCAM1,OPRL1,PCDHGC3,PLP1,PTPN13,PTPRN2,RGR,RGS12,KCTD17,MAP6D1,SYNDIG1,CCDC92,PREX2,SLC6A9,TMCC1,IZUMO4,PEG10,DBNDD2,LHPP,TBCEL,PHF24,BHLHB9,SEZ6L,TRIO,VGF,PMEPA1,SLC17A7" Drug 5643_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "PLA2G6,C1QTNF3,DOC2A,AMH,N4BP2L1,ADGRB3,KSR1,FUBP1,CA4,ARHGEF1,RAB33A,CPS1,DZIP3,DCT,MAGI2,DTNA,DTNB,EFNB3,ING4,EFS,CEND1,REEP2,FGF13,FGFR3,FLNC,RUNDC3A,GNAS,PRUNE2,GPM6B,STON1,LPAR4,GRIK2,SPACA9,GRM8,HNMT,SMAD1,AFDN,CD200,MYCN,NF1,NTRK3,NUMA1,PFKFB2,WDR25,PTPRE,ZSCAN2,SMTN,OGDHL,SNCA,CDK19,RBM26,ATP10B,MAPK8IP3,POPDC3,ICAM5,R3HDM1,FLRT2,XRCC4,SLC30A3,PAK5" Drug 6815_DN Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABAT,ADCY6,SLC12A5,ADRA1D,AP2A2,SEMA6A,BIN1,APBB2,CFLAR,SYNJ2,SCAPER,BTRC,CACNB2,TAOK2,QKI,SIPA1L1,PDE4DIP,FAM169A,HDAC4,SLC12A6,EDNRA,SIDT2,ING4,TNK2,LRRC23,EZH1,SCML2,KAT8,FGFR1,IQCG,DPYSL4,GLYR1,MAPT,TM6SF1,NACA,PCDH9,PDE3B,SLC25A23,FSD1,APTX,PEX5,RAB3IL1,RGS10,SH3BP2,SLC1A7,SMTN,SLC9A5,ZKSCAN3,KDM4B,IQSEC2,NCDN,PHLDB1,IQCE,TMEM121,CHST8,CDK20,ZBTB14,ZNF45,WNK1,EMSY" Drug 7217_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "KIDINS220,APBA2,GAS7,PRX,CACNA1I,BAIAP3,CA4,CACNB4,CALB2,CDH2,TAOK2,MYRIP,EXOG,DPP6,ELAVL2,LRRC23,RASGRP2,MTSS1L,DLC1,KIAA1109,BAIAP2,FHL1,C1orf61,TPK1,GLS,GNAL,GNAO1,GNAS,GPR37,PCLO,KCNF1,VWA5A,AFDN,NDUFA5,OPCML,OPRL1,PDE3B,PDE4D,DUSP26,TNPO2,PRKAR1B,PTN,GSTCD,PLPPR3,SYBU,SLA,SLC11A1,LIMCH1,KDM4B,WDTC1,NPAS3,TAC3,R3HDM1,TPD52,AMACR,TRPM2,VAV2,SPHK2,DNALI1,PHTF2" Drug 5099_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "MTUS1,APC,GAS7,ARHGDIG,ARSE,DNAH17,N4BP2L1,CACNG1,REPS2,FOXN3,HOMER3,ENTPD4,CSF1,CTNND2,MYEF2,DTNB,ST8SIA3,EDNRA,HIPK3,LRRC17,EPHA5,PIPOX,CORO2B,B3GAT1,ERAP1,SIGLEC8,ZNF276,GNG3,STON1,GRIK1,GRIK2,ADAMTS13,SOX21,GUCY1A2,BACH2,ICA1,MAN2A2,LYRM9,NDUFA5,NF1,PDGFRA,MINDY2,PPP5C,MAPK7,FAM120C,C1orf54,RGS10,RGS12,RPS6KA2,SH3BP2,KANSL3,ZNF334,SPTAN1,SAMSN1,PHLDB1,ARHGEF12,AMACR,SSBP2,LAT2,NUP214" Drug 4949_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "SLC12A5,NME5,SEMA6A,AMPD3,KCNAB2,FAM131A,SEMA4G,ARHGAP5,CDK5R1,SLC16A4,CLGN,CSF1,CTH,RIMS2,TBC1D5,SIDT2,EGFR,LRRC17,STX2,PTK2B,ZNF589,FGF13,GAD2,GAP43,SRCAP,PCDH17,RUNDC3A,RND1,GLYR1,GPM6B,ICA1,IL6R,KCNJ4,LIG4,ADAM22,RETREG1,PPARA,CEP41,PTHLH,ELOVL2,ZNF493,EMID1,SYNDIG1,CLIP1,AMBRA1,LIMCH1,KDM4B,PDZD2,ZBTB43,RGL1,PHLDB1,AJAP1,TACC1,TCF7L2,ARHGEF12,TMOD1,PARD3,XRCC4,ZBTB14,GDPD5" Drug 2366_UP Ethisterone [434-03-7]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABHD6,ANK1,ANK3,PPP4R4,CAPRIN2,CADM3,KIF1A,MPDZ,FGF17,BMP7,CDK5R1,MAP7,CDH2,NRG2,VCAN,CTNND1,CTNND2,ZFYVE16,ZNF337,NTM,RABGAP1L,TRAPPC9,RCAN1,DYRK1A,ST8SIA3,SEZ6L2,HEYL,SIDT2,EPB41L1,MTSS1L,CACNG2,KIAA1109,ERAP1,SIGLEC8,POLL,GNAL,LPAR4,SCRG1,AFF1,NF1,NNAT,P2RX7,GPR173,FSD1,PPARA,PPP2R5C,PEX5,RALGDS,FOXRED2,MRAS,SLC11A1,KDM4C,VAMP1,EXOC7,SZT2,AHCYL2,TK2,TPM1,SSBP2,VGF" Drug 3996_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "PPFIA4,DDO,SLC4A4,ADGRB2,BMP7,SYNJ1,BAIAP3,CDK5R2,CACNA1D,CACNB4,CALB2,CAPN3,TPP1,CNTFR,IQCK,CABP1,AKAP5,NCOR2,CSF1,CSF1R,PDE4DIP,CNTNAP2,SPOCK2,DCT,SGSM2,ARNT2,TRAPPC9,ST8SIA3,AGAP2,B3GAT1,FYB1,GAB1,ITGA7,KCNJ5,KCNJ9,KCNN1,PACRG,CD200,MSR1,NF1,NOS1,PALM,PHKG1,POU6F1,GDPD2,PTAFR,RASGRF1,SLC6A15,RGS4,FUZ,PKNOX2,SP2,INKA2,ACSBG1,KAZN,RIMBP2,TRO,WNK1,PRDM2,DNALI1" Drug 4702_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ASIC1,NDRG2,SEMA6A,GAS7,PDE8B,BRINP2,ATP1A2,ATP1A3,CACNG1,CACNA2D2,GPR37L1,NRXN3,QKI,HAPLN1,SEC14L5,ST8SIA3,FAM13A,MBNL2,SRPK3,FABP7,KIAA1109,AFF2,GABRA2,ZNF44,GCNT2,CSDC2,GPM6B,GPR37,PCLO,GRIK2,GRIN1,GRM7,GUCY1A2,PTGDR2,INPP1,KCNN1,MID1,AFDN,NF1,CAMKV,MAPK10,MARCH1,ZMAT4,TRIM68,ZFHX4,SCN2B,MRAS,ASAP3,ARHGEF40,ZKSCAN3,IQSEC2,MAPK8IP3,DOCK9,TMOD1,LAT2,WNT7A,ZIC3,PRDM2,PLSCR4,FAM13C" Drug 2466_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "MRTFA,BIN1,CDC42BPA,ANK3,CCDC181,MPDZ,BMP7,GYG2,BAIAP3,CFAP410,CALB2,THSD7A,SEPT7,CDC42,LARGE1,CDO1,LHX2,ZFYVE9,NRG2,NCOR2,ABCG1,SIPA1L1,ARMCX2,SV2B,SORBS3,ELAVL3,DMTN,REEP2,FGF13,B3GAT1,ZNF276,GNAO1,TPPP,GRIK5,GRIN1,HRH3,IL6ST,MAP4,PCSK2,CAMKV,ZDHHC14,ASIC4,SLC11A1,SMARCD3,SNCA,PALLD,HECW1,SPTAN1,SPART,IQCE,SMG6,PCDHGA10,PSD3,TK2,CABIN1,TRPC1,ZNF711,ZNF32,SPHK2,SLC17A6" Drug 610_UP monastrol; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ACTN2,ADCY6,LTBP4,APOC1,PPFIA3,ARNTL,EIF4G3,SGCE,CAMK2B,MAGI1,CHN1,TAOK2,CREM,CRMP1,DZIP3,KIAA0586,RCAN1,TOM1,SGK2,EFNB3,TNK2,LRRC23,KCNMB2,VPS26C,EXTL2,DLC1,OLFM1,SCARA3,FAM49B,NSG1,GLS,KLF12,KIF5A,MAP4,MAPT,MMP16,ADAM22,MYT1,NF1,NOS1,NPTX1,NTRK3,PMS2,PACSIN1,PPM1B,MASP1,PTPRD,PTPRN2,GALNT10,ST6GAL1,LIMS2,SLCO1A2,TSPYL2,SPART,NSFL1C,OBSL1,TF,TRPM2,PDIA2,WNT7A" Drug 5488_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABAT,ADCY2,ADORA2A,SEMA4G,ARHGDIG,MARK4,ADAM23,MTMR2,ARHGAP33,CNTN1,VCAN,EDRF1,DAPK1,BRINP1,CNIH3,SRGAP3,ELN,BAIAP2,ANKFY1,ZNF44,RUNDC3A,GPM6B,STON1,NR3C1,RASSF8,AFF1,NF1,NNAT,NPPA,NUMA1,KCNK10,FAM120C,RAB3A,RNASE1,MYH14,ZNF821,RASA3,SH3BP2,SLN,PEG10,THSD1,ASTN2,TAC3,SEMA4A,MCF2L,SZT2,CHST8,GPR161,TGFBR3,THRA,TMOD1,TNS1,PIK3R5,TRH,ZMYND8,HIRA,LMF1,EVI5,GDPD5,KCNAB1" Drug 2761_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "NME5,PLA2G6,LTBP4,APOC1,BACH1,SYNJ2,MTMR3,CA4,HAP1,USP2,NEURL1,LHX2,STOML1,FADS2,NCOR2,PDE4DIP,RIMS2,RIMS3,ZNF804A,DMPK,SLC12A6,OPTN,MBNL2,STX2,ETV1,ZNF589,KIAA1109,GLS,PRUNE2,GPER1,ADAMTS13,GRM1,IRF8,MAP4,MX1,PCBP3,FA2H,CEP41,SAMD9,ELOVL2,C1orf54,EMID1,RPS20,SATB1,DOCK10,SMTN,ZCCHC24,ARHGAP26,IQSEC2,CRTC1,PCDHA5,HEY2,CABIN1,TPM3,TTPA,FAM155A,VAV2,PRDM2,EPM2A,NUP214" Drug 3544_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "AP2A2,APC,ADAM15,CFLAR,SCARB1,VAX2,ARHGAP32,INTS1,MED12,DSCAM,DTNA,PHC2,MRNIP,ANKFY1,COPS8,FERMT2,NR3C1,RNFT2,HNMT,ICA1,IL6ST,ITPKB,IPO5,MITF,MPP2,OGDH,LRP12,PMS2,MINDY2,PPP5C,TMEM104,RGS10,SEC61A2,SLC25A36,GSTCD,EPN2,SHANK2,ELMO2,WDTC1,ZCCHC24,UHRF1BP1L,SS18,MAPK8IP3,CEP68,AJAP1,SEMA4A,DNMBP,EHBP1,SATB2,TRIM2,AHCYL2,TMPO,RUNDC3B,ZMYND8,HIRA,NSD2,ZBTB14,MAP3K12,MPPE1,AAAS" Drug 5518_UP Carbamazepine [298-46-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABR,ACTN2,C1QTNF1,MRTFA,BIN1,AMT,CDC42BPA,AQP6,PLA2G4C,CFLAR,LDLRAD4,CACNB4,HAP1,MYOM2,KCNAB3,TAOK2,CLCN4,C2CD2,VCAN,SDC3,RIMS2,RASSF2,DGKG,SLC12A6,AASS,FGF13,AGAP2,NSG1,SIGLEC8,GPR162,C1QL1,RUNDC3A,RND1,GPM6B,RASSF8,KCNB1,LAMA2,NF1,ODF2,POU3F4,WDR25,ELOVL2,RALGDS,CCDC25,CCDC102B,RPS6KA2,SYNDIG1,SBF1,ZFP2,PKNOX2,CCDC88A,SLC20A2,KDM4C,PEG10,KIAA0930,PSD3,CRTC1,TK2,VSNL1,PLSCR4" Drug 6821_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ALK,MRTFA,BIN1,EPB41L5,PPP4R4,SYNJ1,NEURL1,ARHGAP33,CLGN,ADGRG1,RAB33A,PLAA,CLCN4,CLTB,COL9A3,NECTIN3,CPS1,MAML1,RUSC2,SV2B,SRGAP3,DRD1,DTNA,ACSL4,ZNF589,FOXG1,SORBS1,RUNDC3A,GNG3,GRIK5,HLF,HNMT,ITGAM,MIA2,MID1,MMP16,ADAM22,MSR1,NEFM,OPCML,PENK,TMOD2,PTAFR,PTHLH,TCP11L1,SEMA6D,ITSN1,ASAP3,SPTB,CAMTA2,MAPK8IP3,ARHGEF9,KIAA0930,DOCK9,BEX4,TPM3,UCHL1,HPS4,ITM2C,KAT6A" Drug 6145_DN Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ASIC1,MTUS1,PKP4,APAF1,NUMB,SLC4A4,SYNJ1,CHM,PLAA,NMT2,IQCK,C2CD2,RBM12,PLXNC1,IRAK4,TNK2,CD320,PDLIM5,FYB1,SEPT9,INPP5K,TXNL4A,RAB40B,GPD2,IPO5,MIA2,ZNF862,NUMA1,PLCB2,SMIM7,PMP22,LRP12,MINDY2,PPP3CC,TMEM231,CEP97,RAD52,RGS10,UEVLD,FOXRED2,SLC2A5,FAM214B,KBTBD4,ZNF667,SNCA,KDM4C,ARHGAP26,SS18,FAM168A,CAMSAP2,SIN3B,TCF7L2,THBS4,SLC44A1,TNS1,RBFOX2,ZKSCAN5,XRCC4,ZBTB38,KCNAB1" Drug 4715_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADCY2,NME5,MRTFA,PDE8B,ATM,SLC4A4,CFLAR,CA4,ARHGEF1,NEURL1,CDH8,MAGI1,TAOK2,RGS6,FAM169A,TBC1D5,MAML1,PHYHIP,SMG7,EFNB3,EGFR,EFS,ATP8A1,FGFR3,CAMSAP1,AFF2,ZNF44,GATM,GLYR1,GRIK5,HLF,HPSE2,IL6ST,MID1,NCAM1,NF1,PMP2,MAPK10,NKAIN1,SUGCT,TCP11L1,MRAS,ASAP3,SMARCD3,SNCA,WDTC1,EMC1,PHLDB1,PLCB1,SYN2,SYP,TCF4,DMXL2,CHST8,ZMYND8,WNK1,SEMA3B,MVB12B,CAMK1G,NUP214" Drug 3085_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABHD6,KIDINS220,BIN1,FGD2,CNTNAP1,APAF1,APC,APOC1,PDE8B,SLC4A4,RUNX1T1,MYOM2,LARGE1,CDR1,RAB33A,ZFYVE9,ABCG1,CRYM,CSNK1E,EDRF1,SPOCK2,DYRK1A,CELSR3,EPB41,EPHB1,PRELID3A,SIGLEC8,ATP8A2,GFER,GNAO1,GNG4,MCHR1,GRM1,GRM7,PADI2,NXPH3,ELOVL5,SCIN,KCNA2,MGAT3,AFDN,SLCO1C1,OMG,POU3F4,PRPH,MASP1,CNNM2,BCAS3,RAD52,ZDHHC14,ASAP3,ZSWIM8,IZUMO4,DDN,ROBO3,TBCEL,TRPC1,VAV2,SLC17A7,KCNAB1" Drug 3692_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "C1QTNF3,MRTFA,AMT,APAF1,SLC4A4,ST3GAL5,SCAPER,MYRF,BAIAP3,BTRC,CAMK2B,PLEKHB1,CLCN3,PICK1,AKAP7,TCEAL2,NCOR2,PHF14,RABGAP1L,DMPK,CDON,DSCAM,IRAK4,MRNIP,SORBS1,GAD2,SRCAP,PCDH17,KCNMB4,GPR17,GPR19,CACFD1,RASSF8,HSD17B1,TJAP1,VWA5A,NDUFA5,PIK3R1,CEP41,RAD52,KCTD17,IL17RB,ASAP3,FNDC3A,PREX2,CCDC88A,SHANK2,RBM34,ZHX3,SPTB,DDN,LHPP,ARC,TK2,R3HDM1,CDK20,RPRM,NT5M,PCBP4,GAN" Drug 4394_UP Levodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ASIC1,ARHGDIG,CDK13,BAIAP3,CACNA1A,HIP1R,P2RX6,CD86,TAOK2,LY86,RIMS2,CTIF,DTNB,DYRK1A,AASS,EIF4G2,ELAVL3,ELN,IGSF6,SPEG,ST3GAL6,KIAA1109,OLFM1,HPCAL4,GABRA2,ADAM28,GPM6B,GRIK5,GRM2,ITGA7,LMO1,MAPT,MGAT3,ADAM22,BCO1,MYCN,NTRK2,P2RY1,SNTG1,GPR85,PMP2,CCDC40,RPS6KA2,SEMA6D,ZFP2,SH3BP2,KANSL3,DOK5,IZUMO4,ARHGAP26,ATP10B,TROVE2,POPDC3,TBCEL,WSCD1,DOCK9,TNS1,WIPF1,LAT2,ADAMTS9" Drug 5804_UP Lidoflazine [3416-26-0]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ASIC1,LTBP4,ALK,BACH1,BTRC,CACNA1D,SYNGR3,MAGI1,FOXN3,CHRNA4,WHRN,COL9A2,AKAP5,ABCG1,FAM131B,SPOCK3,DMPK,EDIL3,RASGRP2,PIPOX,F5,CORO2B,ST3GAL6,HPCAL4,AFF2,GABRA2,ERAP1,SIGLEC8,SRCAP,RUNDC3A,SPACA9,GRIK5,GRM8,ADAMTS6,CELF3,HTR2A,KHK,KIT,VWA5A,AFF1,TAGLN3,NHLH1,NPTX1,GPR85,PENK,PID1,ACSS3,FRMPD1,ARHGEF40,SNCA,SSTR2,DIP2A,ACSBG1,COBL,PCDHA5,THBS4,CHST5,FLRT2,REEP1,STMN4" Drug 6714_UP Hesperidin [520-26-3]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ACTN2,ADGRF5,SPARCL1,SEMA6A,LTBP4,DOC2A,PRX,ATP2B3,N4BP2L1,ADAM23,CACNA1I,BAIAP3,LDLRAD4,CAMK2B,LARGE1,CRLF1,TAOK2,ARHGAP22,NRXN2,CSF1,ERC2,CTNND2,TOX,DYRK1A,EDN3,TNK2,DLC1,ATP8A1,FGFR1,FOXG1,GNAL,STON1,GRIN1,AP4S1,HPCA,ITGA7,KCNC1,VWA5A,SMAD1,ADAM11,ADAM22,NOVA2,PDE3B,RETREG1,PPP1R1A,SLC6A15,CRTAC1,KLHDC8A,PNMA8A,GSTCD,PRR5L,RPS6KA2,STUM,SLC6A9,SOX2,HECW1,TACR1,SEMA4A,TLR4,REEP1" Drug 2357_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "NDRG2,ADRA1D,AP2A2,NR0B1,BIN1,AMT,SHROOM2,ALDH4A1,KIF1A,ADAM23,HIP1R,LARGE1,STOML1,NRG2,SH2B1,VCAN,BRINP1,SPOCK3,DRP2,EDN3,EFNB3,CAMSAP1,AFF2,NSG1,B3GAT1,SEPT9,GFER,GLS,POLL,GPM6B,LILRA2,HPSE2,TJAP1,IGSF1,MYCN,NUMA1,PCDHGC3,PCSK5,LRP12,TMEM104,PTAFR,FAM184A,RGS4,TMEM156,SEC14L1,MRAS,FRMPD1,SLC11A1,SLC15A2,ZBTB43,ZC4H2,RGL1,RPGRIP1L,PHF24,TNS2,CRTC1,PIK3R5,FLRT2,XRCC4,HPS4" Drug 2702_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "NDRG2,APAF1,MADD,CLGN,CLCN4,CSF1,ARHGEF10,CSNK1E,SLITRK5,CTH,CTNND1,DAPK3,SV2B,CNNM1,ABI2,ELN,CORO2B,KAT8,NBEA,ZMYND11,INPP5K,ALDH1L1,ZNF276,GPR22,GRB10,PADI2,ATXN2L,LIG4,MDM4,MYBPC1,MYH3,MYO6,NEUROD1,PDE4A,FSD1,MAPK8,CNNM2,BCAS3,CEP97,RAD52,RGS10,RPS6KA2,GALNT10,CCDC92,ANKRD6,SLC1A3,PREX2,EPN2,IZUMO4,IQSEC2,LHPP,MAPK8IP3,KAT6B,TNS1,CDK20,TPM3,SMUG1,ZMYND8,FLRT2,CLIP2" Drug 4177_DN Gelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADORA2A,ADORA3,BIN1,APC,FAM131A,MARK4,ALDH7A1,NRP2,ARHGEF1,SEPT7,CDH18,CLCN4,CLTB,LY86,WHRN,SNCAIP,GREB1,TMCC2,EXOG,EFNB3,PLXNC1,ELN,VPS13B,IGSF6,DLC1,FHL1,GPR153,SEPT9,ALDH1L1,LYVE1,GRIK5,GSN,KCNMA1,ZNF862,NF1,NUMA1,PENK,SERPINI1,RIPOR1,RNASEL,MAP6D1,SBF1,ZNF821,PEX26,SNCA,IQSEC2,ZBTB43,NPAS3,THSD1,INKA2,ARC,SEMA4A,ZEB1,HEY2,TMOD1,KAT6B,TNS1,XRCC4,SPHK2,SYNC" Drug 3605_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "SYN3,LTBP4,BIN1,APAF1,PPFIA3,MARK4,CACNA1I,CACNA1D,CALB1,CALB2,CAMK2B,RUNX1T1,CLCN4,WHRN,TCEAL2,CSF1,OSBPL3,PLCH2,CTIF,DBT,ELMO1,SGK2,FAM13A,ELAVL2,EN2,PIPOX,AFF2,GFER,ITGAM,KCND3,KCNMA1,KHK,MID1,MSI1,MYT1,NF1,OPCML,P2RY1,PCDHGC3,C19orf57,ELOVL2,RAD52,ZMAT4,KLHL11,ASAP3,PKNOX2,LIMCH1,IZUMO4,ARC,HIF3A,GPR161,ICAM5,TMOD1,TPM2,OSBP2,FLRT1,LAT2,KCNK12,SLC30A3,SCG2" Drug 3351_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ACHE,ADRA1B,NME5,CDC42BPA,ANK1,FAM131A,CDK10,CDK13,RIPK1,BAIAP3,LDLRAD4,ARHGEF1,SCARB1,ARHGEF2,CHM,TAOK2,NECTIN3,ENTPD4,DOCK4,HP1BP3,RUSC2,ATN1,HIPK3,MBNL2,APC2,PTK2B,FGFR1,FGFR3,FHL1,DLL3,GAB1,GAD1,SIGLEC8,GNAL,NR3C1,GRM8,NF1,CDK18,PDE3B,PFKFB2,STRN3,ZSCAN32,PTPRH,C1orf54,MYH14,ASAP3,DHX30,CXXC4,COA1,WDTC1,ZC3H13,DMXL2,TNS2,PCDHA6,TEX15,TNS1,UCHL1,PLPPR2,ZNF45,DNALI1" Drug 2746_UP Tomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADORA2A,ADRB2,KIDINS220,NME5,AK2,BIN1,CDC14B,MARK4,N4BP2L1,KSR1,BAIAP3,CA4,CACNG1,CCKBR,LHX2,AKAP7,RIMS3,TMCC2,PLXNC1,TENM1,DMTN,NRN1,FGF13,SIGLEC8,POLL,GUCY1A1,ATXN2L,IRF8,KCNH2,MAP4,GIT1,MYO7A,NELL2,NF1,NRGN,KCNK10,FAM184A,RNASE1,SLA,SLC8A1,SHANK2,KDM4B,ZCCHC24,HECW1,IQSEC2,NCDN,POPDC3,TACR1,TCF7L2,PCDHGA10,CRTC1,DICER1,CHST8,THBS4,SEZ6L,TPM2,SLC13A3,SYNC,EMSY,KCNAB1" Drug 1109_UP 3-hydroxy-(D/L)-kynurenine; Up 200; 9.2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADD3,APP,MADD,ATP2B1,MTMR9,RIPK1,MPDZ,CFLAR,SYNJ1,SYNJ2,MTMR3,RAB29,CLCN3,ARHGEF10,CTNND2,KIAA0586,DLG3,DTNA,PCOLCE2,RABEPK,STX2,CAMKK2,MPP6,NCKAP1,GSN,PADI2,AGFG1,TJAP1,MARK3,NEK1,PLEC,PPP3CA,PRKACB,PTK2,ZSCAN32,CLIP1,FOXRED2,ATXN1,ASRGL1,URGCP,WDR47,ELMO2,SMARCC2,KDM4B,SPATA7,UHRF1BP1L,TROVE2,CEP68,DNMBP,CAMSAP2,FAM208A,ATP13A2,BEX4,RBFOX2,SSBP2,UBTF,XRCC4,ZBTB38,WIPF2,NUP214" Drug 4504_UP Iopromide [73334-07-3]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "AMPD3,PDXK,BMPR1B,CBS,CD86,ADGRG1,CLCN4,HOMER3,NCOR2,ARHGEF10,PDE4DIP,PHF14,MAML1,ARMCX2,DNAJC6,MFAP3L,DMPK,ST8SIA3,EDNRB,EFNA3,EPHA5,APC2,EZH1,OLFM1,FLT1,DCTN2,TBR1,ZNF44,RND1,CACFD1,SOX21,PADI2,KLF12,IRF8,JAK2,MMP17,GIT1,MT1M,MYL3,MYO7A,NPPA,NPR2,PDE4D,ENPP2,MAPK7,PTPRN2,ZSCAN2,RGS12,RASA3,FBXO11,SMARCA4,TSNAXIP1,FNBP1,ZBTB43,SMG6,ZFPM2,TPM3,MVB12B,EPM2A,PHTF2" Drug 5092_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "MRTFA,ANK1,SEMA7A,ASTN1,CADM3,LDLRAD4,VAX2,CABP1,COL9A3,CRY2,RIMS2,DRD1,DTNA,ABCC9,ST8SIA3,SORBS3,SRPK3,DLC1,FYB1,GAB1,ZNF44,SIGLEC8,LYVE1,STON1,GRIK2,CACFD1,ADAMTS8,GRM2,IRAK3,HLF,HPSE2,HTR2A,ICA1,KIF5A,KIF5C,KIT,MAPT,AFDN,MMP16,MYH3,NOVA1,PFKFB4,PRKCB,PTH1R,TMEM231,RFX2,RNASEL,ROM1,SLC2A5,SOX10,ZHX3,VAMP1,TAL1,TPM1,TRO,VIPR2,LAT2,KCNK12,ADAMTS9,KCNAB1" Drug 3416_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "DPF1,ARID1A,KIDINS220,C1QTNF3,SRPX,CDC42BPA,PKP4,PPP4R4,ALDH4A1,CFLAR,CACNB2,NEURL1,SLIT2,TPP1,FAM189A2,PICK1,COL9A3,MICAL2,SDC3,MAML1,ELN,MTSS1L,SCARA3,DPYSL4,OGA,GAD1,POLL,LPAR4,LAMA2,MAOB,MBD1,MIA2,NF1,NUMA1,PDE3B,SSH1,LRP12,RGS12,ZFHX4,CARF,ASAP3,SMTN,ARHGEF40,SLC9A5,BTBD7,SNCA,ST5,MAPK8IP3,PHLDB1,AJAP1,POPDC3,TACR1,ROBO3,PCDHGA10,TGFBR3,TK2,PARD3,ZKSCAN5,VAV2,ZIC3" Drug 2665_UP "ICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ABHD6,ADCY2,MTUS1,FGD2,SEMA4G,PPP4R4,CADM3,CACNB4,P2RX6,SYNGR3,CHRNB2,CRY2,SIPA1L1,PDE4DIP,DCAF4,SPOCK2,DNAJC6,ATN1,RCAN1,HIPK3,MBNL2,LPAR6,EIF1,OLIG2,FHL1,PDLIM5,GAB1,GALC,GATM,GFRA1,LILRA2,RAPGEF1,GRM7,ATXN2L,IL6ST,KCNQ3,KIF5C,MAP4,MEF2C,MSR1,MX1,PFKFB2,PLCD1,PLEC,PPARA,PTPRH,MYH14,RPS20,SHANK2,TMCC1,RAP1GAP2,CAMTA2,DNMBP,PSD3,CRTC1,CHST8,AP4E1,TRPC1,TRPS1,PHTF2" Drug 2908_UP Nifurtimox [23256-30-6]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ACTN1,ARID1A,NDRG2,PLA2G6,ANK2,ANK3,AQP4,PDE8B,ATP6V0A1,MTMR2,HAP1,CDH10,CDO1,HOMER3,WHRN,MICAL2,CNTNAP2,KLHL3,DMD,ATN1,DYRK1A,SORBS3,EPB41,PDLIM5,ATXN2L,MYO7A,KCNK10,PDE4D,CAMKV,NLE1,TNPO2,FA2H,POU3F4,PPARA,LRRN3,PRKAR1B,PTPN13,RAB3A,RASGRF1,MYH14,FAM102A,ST6GAL1,BTBD7,SMARCD3,ARHGAP26,SPTAN1,SPTB,VAMP1,SYT5,TCF7,TJP1,TMOD1,DAAM2,KCTD2,RBFOX2,CDK20,RUNDC3B,FLRT2,SH3GLB2,PARP11" Drug 7259_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "TRMT9B,AMH,PPFIA3,RAB29,MYRF,KRIT1,CBFA2T2,ZFYVE9,NCOR2,ARHGEF10,CNTNAP2,SLITRK5,TOX,BRINP1,RUSC2,LYPD1,RABGAP1L,ING4,ANKMY1,ATP8A1,TESK2,ERGIC3,SIGLEC8,GLRB,POLL,GNAL,SPACA9,MAN1B1,SCIN,INPP5B,KIF2A,MITF,NOVA1,NUMA1,GON4L,PEX5,RAD52,ZCWPW1,RGS4,RGS10,RGS12,RYR1,SCN8A,SH3BP2,SMARCD3,MYH15,ZSWIM8,SPP1,ZBTB43,SS18,CEP68,ZEB1,TK2,BEX4,R3HDM1,TRIO,EMSY,EPM2A,KAT6A,PHTF2" Drug 2465_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "C3orf14,SLC12A5,AGT,ANK3,BCAS1,DDX3Y,KSR1,BMP7,CDK5R1,GYG2,CDH10,AKAP6,CREM,CRYM,NTM,DMTN,RASGRP2,F5,FER,BAIAP2,GAA,GABRA5,SEPT9,GPR75,GPM6A,GUCY1A2,KLF12,HNMT,HTR2A,MAP4,MDFI,MYT1,NAP1L2,SLCO1C1,NPPA,PFKFB4,PPARA,LRRN3,TMEM104,TCP11L1,GALNT10,NLGN1,RPH3A,SLN,ZC4H2,SYT5,CAMSAP2,PCDHGB6,PHF24,ATP13A2,TIAM1,TRIO,TMPRSS5,FAM155A,CLIP2,WNT7A,KLC2,SLC13A3,KCNAB1,PLSCR4" Drug 3577_UP Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADGRF5,LTBP4,SEMA7A,APC,CDK13,ATP2B3,SYNJ1,SYNJ2,CACNA1I,CFAP410,CACNA1D,FOXN3,ASIC3,CNN3,CPS1,ARHGEF10,DBT,CNIH3,NTM,ST8SIA3,HEYL,ELAVL3,FGFR1,BAIAP2,FHL1,FOXF2,SIGLEC8,RND1,ATF7,SPACA9,GRIN1,GRM1,ELOVL5,KCNN1,KIFC3,LMO1,MMP17,ADAM22,NF1,NTRK2,NTRK3,PLTP,LRRN3,PROX1,PLPPR1,RGS12,TCP11L1,RPS6KA2,RYR1,SALL1,CNKSR2,SLC2A5,KANSL3,SLC9A5,SNCA,ZNF415,INKA2,WSCD1,VIPR2,ADAMTSL3" Drug 5565_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "DPF1,ADCY2,ADORA2A,ADRA1D,AMPD3,AMT,APOC1,CHRD,CCDC181,SCAPER,CACNG1,CAMK2B,CLDN10,WHRN,COL9A3,IFFO1,TCEAL2,RASSF2,SRGAP3,TMCC2,DMPK,DRD1,DTNB,DYRK1A,EDNRA,RASGRP2,ATP8A1,AGAP2,LYVE1,GNAS,STON1,GPER1,GPR37,KLF12,KCNJ5,MOBP,MSR1,PCDH9,PIK3CD,RETREG1,PLCB2,LRP12,MAPK10,PTPRB,PTPRO,PTX3,ZMAT4,RGS4,RYR1,SH3BP2,ZNF423,ATP10B,RGL1,TAL1,TCF7L2,TRPM2,WIPF1,TRIM9,WNK1,DPF3" Drug 6067_UP Ricinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADCY2,AMH,BIN1,APC,PRX,ATP2B2,CFLAR,CACNG1,LY86,HAPLN1,CSF1,ARHGEF4,DCAF4,SEC14L5,SRGAP3,EBI3,LRRC23,LRRC17,PIPOX,TUBB4A,FGFR1,GABRA2,GAD1,CYP46A1,GFAP,GPM6A,GRM7,GSN,GSTM5,KCNB1,KCNJ4,KHK,MPP2,MX1,MYT1,P2RY13,CDK14,RETREG1,PLCD1,PPP2R2B,MAPK8,SAMD9,C1orf54,RGS12,SH3BP2,HKDC1,FAM214B,SLN,SNCA,PEG10,SPTB,ATP10B,EXOC7,TCF4,DMXL2,SZT2,SLC19A3,TRPC3,MICAL1,SLC26A10" Drug 6911_UP NS-398; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "AP2A2,SYT13,CDC42BPA,APC,SEMA4G,PRX,MARK4,ATM,ATP2B1,KIF1A,MYRF,CACNA1D,CBFA2T2,SOCS6,DNAJB5,COL4A5,CSF1,CSF1R,PPP6R2,GIT2,RABGAP1L,SEMA4D,GLYR1,GPER1,CACFD1,HNMT,TJAP1,IL6ST,KIF5C,MATK,TM6SF1,CD200,SLC11A2,PLCD1,PACSIN1,PPP5C,VPS13C,GON4L,WDR25,CCDC40,RAD52,RGS3,RGS10,KCTD17,SEC61A2,ROM1,EMID1,PREX2,PPP4R3A,KIF13A,FAIM2,RBM34,WDTC1,ZCCHC24,PBLD,CLDND1,KCNK12,ADAMTS9,SCG2,GAN" Drug 6994_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ASPHD1,APLP1,MARCH3,CAPRIN2,ASPH,ALDH7A1,CFLAR,CDK5R1,SCAPER,MTMR3,KYAT1,B4GALT6,FAM189A2,CNTN1,MED12,SLC12A6,SIDT2,EGR3,TNK2,CDKL3,RRAGB,FECH,FER,DPYSL4,FYB1,MSL3,GRM8,HNMT,ITPKB,KCNK1,IPO5,MAPT,MGAT3,MPP2,NUMA1,SMOX,NECAB2,MAPK7,MAPK8,MAPK10,SAMD9,ZSCAN32,CCDC40,RAD52,GTDC1,PAQR6,SYBU,CCDC88A,ZKSCAN3,SPTAN1,ELOVL4,VAMP1,PLCB1,ZKSCAN5,ZIC3,SEMA3B,NAV2,KCNAB1,FAM13C,RNF170" Drug 2860_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "RALGAPA1,NDRG2,ADCY2,ADORA2A,MTUS1,PLA2G6,MRTFA,AMH,AMPD3,GAS7,ALDH7A1,CFLAR,CACNA1I,CALB2,ARHGEF2,FOXN3,TAOK2,SLIT2,ARHGEF6,CPS1,VCAN,MAML1,DCT,ZNF804A,SRGAP3,DNM2,OPTN,ING4,LRRC23,ERCC2,NCALD,FGFR1,FHL1,FAM49B,FYB1,GAP43,GCNT2,STON1,GRIN1,GRM1,GSN,ICA1,KCNN1,KHK,LAMA2,VWA5A,MAPT,TM6SF1,MITF,MSR1,NTRK2,CEP41,RYR1,EPN2,SLC22A4,SNCA,ARHGAP26,DICER1,PRDM2,ST7" Drug 5734_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "SLC12A5,PKP4,APOC1,APP,N4BP2L1,ADGRB2,BRSK2,CBS,PLEKHB1,STOML1,RAB26,IQCK,RIPOR2,DAPK3,MFAP3L,C2CD2L,SPOCK3,SRGAP3,RABGAP1L,DMPK,ING4,MTSS1L,NCALD,IGSF6,SORBS1,HBS1L,NEU3,GPR75,GNAL,SOX21,ATXN2L,HSD17B1,IL6ST,ITGA7,ITIH2,MGAT3,ADAM22,PDE2A,PDE4D,GPR85,PPP2R2B,PPP5C,NEK11,ATXN7,STUM,PPP4R3A,KDM4B,LHPP,AJAP1,SEMA4A,SZT2,FAM189A1,TIAM1,RPRM,VAV1,ZFP37,ZIC3,SEMA3B,NUP214,JPH3" Drug 3343_DN Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ARID1A,ADORA2A,AP2A2,PLA2G6,AMPD3,BIN1,APOC1,ASPH,ATM,BCL2L2,CFLAR,SYNJ2,SCAPER,MAGI1,B4GALT6,BAG4,NCOR1,CSF1,DCAF8,DAPK3,RGS17,DMTN,STX2,DPYSL4,CSPG5,GALC,ZNF276,TXNL4A,RAB30,GLS,POLL,INPP5B,KCNJ5,MAP4,MATK,ADAM22,NF1,NFYA,RETREG1,PLCD1,PRKAR1B,ZSCAN32,CEP97,AMBRA1,SYBU,ABLIM3,BTBD7,ZKSCAN3,KDM4C,THSD1,ELOVL4,PHLDB1,PLCB1,POPDC3,SMG6,ZNF384,TRPC1,PLPPR2,VGF,SEMA3B" Drug 5630_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "DPF1,ADCY6,APAF1,SEMA4G,ARHGDIG,CFAP410,KALRN,USP2,GPR37L1,CHM,LHX2,CLCN4,SULT4A1,AKAP6,AATK,CSF1,CTIF,DCC,C2CD2L,SRGAP3,DMPK,EDNRA,EPHB1,EFS,GAB1,DISC1,GNAO1,GRK4,SOX21,ATXN2L,KCND3,KIF5A,LMO1,NFIX,CNOT4,NOVA2,NTRK2,NUMA1,CDK18,PFKFB2,POU6F1,CEP41,GDPD2,SNRK,PTPRB,RGS12,MYH14,CPEB3,SLC11A1,SHANK2,CAND2,WSCD1,ZEB1,HIF3A,TRPM2,VAV2,VIPR2,SPHK2,SLC30A3,KCNAB1" Drug 6378_UP valdecoxib; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADCY2,ADD2,SLC12A5,C1QTNF3,MRTFA,APAF1,APBB2,ARRB1,RASL11B,CDH8,RAB28,ABCG2,SULT4A1,HOMER3,MICAL2,EDRF1,ZFYVE16,LYPD1,SV2B,DNAH9,SHANK1,ATN1,DTNB,ETV1,DLC1,KIAA1109,CAMSAP1,FOXG1,NSG1,OGA,GAB1,HBS1L,DISC1,ATP8A2,SRCAP,KCNMB4,ICA1,KCNJ5,LSS,MAPT,MATK,MT1M,NRCAM,PFKFB2,SAMD9,PTPRD,PTPRN2,TTLL7,TCP11L1,SLC30A10,CPEB3,BCAN,SLC6A11,MYH15,KDM4B,SCN3B,MAPK8IP3,GPR161,MAP3K12,EPM2A" Drug 3319_UP Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-07 7.14E-03 5.52E-06 6.28E-05 60 197 "ADRA1D,BIN1,APC,APLP1,SLC4A4,LDLRAD4,CACNG1,BRSK2,P2RX6,CDH2,CDH10,TAOK2,STOML1,AKAP7,WHRN,CSF1,SPOCK2,ELMO1,MFAP3L,SLC12A6,MBNL2,PLXNC1,LRRC17,EFS,SPEG,NSG1,GAD2,DISC1,ATP8A2,ALDH1L1,GFER,POLL,GPM6A,GRIN1,GRM7,GRM8,KCNMA1,MDM4,MMP16,NDUFA5,NF1,CNOT4,KCNK10,PACSIN1,RYR1,FRMPD1,BCAN,SLC11A1,WDTC1,SOX2,ZSWIM8,EXOC7,SYNE1,TNS2,PIK3R5,FAM155A,VIPR2,KCNK12,KCNAB1,NUP214" Drug CID000168297 C13932 Stitch 1.46E-07 7.17E-03 5.54E-06 6.30E-05 62 206 "APAF1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1A,CACNA1B,CACNA2D1,CALM1,CANX,KRIT1,SLC5A11,RGN,AIFM1,CD38,ENTPD2,DYNC1I1,ATN1,ELN,EN2,ENO2,PTK2B,PPP1R1B,SCARA3,FOXG1,ATP2C1,B3GAT1,OGA,NEU3,GFAP,PPARGC1A,CRCP,TCERG1,HPS5,PACSIN2,HSP90AA1,MYLK2,IGF1,SCRT2,KCNK3,KITLG,OGDH,OGG1,PAH,KCNK10,ABCB1,PACSIN1,QDPR,FBXW7,RYR1,RYR3,ATXN7,FOXRED1,SLC1A3,TAC1,TAC3,TACR1,NEU4,TJP1,TRPC1,PRTFDC1,JPH3" Drug CID004369374 AC1N9ZZC Stitch 1.51E-07 7.39E-03 5.71E-06 6.50E-05 49 149 "KCNH8,ADRB2,ANK1,ANK2,ANK3,MYH7B,MADD,KIF1A,SYNJ1,AP1M1,C5,CACNA1A,DDR1,SPAG9,CFL2,CLTC,MAP4K4,SLC32A1,DCC,SNAP91,DPYSL2,PNMA2,HBS1L,ATP8A2,GATM,FERMT2,GSN,PTPN5,KIF5A,KLC1,MYH3,MYH6,MYH7,NCAM2,FXYD1,PPP3CA,SIDT1,PTK2,ROBO1,RYR1,RYR3,SCP2,SLC14A1,UNC5B,ST5,MAPK8IP3,TRIO,NAV3,NAV2" Drug CID000001216 AP-5 Stitch 1.54E-07 7.57E-03 5.84E-06 6.65E-05 44 128 "ADORA1,CACNA1D,CACNA2D1,CACNB2,CAMK2B,CAMK2D,CHRM1,CHRNA4,EIF4G2,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,CPLX2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PACRG,NOS1,NRGN,PRKCG,SALL1,JMJD6,SYN2,TACR1,RUSC1" Drug 3086_UP Fluspirilen [1841-19-6]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.60E-07 7.83E-03 6.02E-06 6.85E-05 59 193 "SYN3,ARID1A,ADD2,AMH,ANK3,CDC14B,ATP6V0A1,BMP7,CACNA2D1,THSD7A,REPS2,LARGE1,CACNA2D2,RAB33A,CNTN1,HAPLN1,KIAA0513,CTIF,BRINP1,CNIH3,SV2A,ARNT2,DLG4,CDON,DYRK1A,C3orf18,ERBB2,ETV1,FGF1,FGFR1,PRELID3A,SIGLEC8,C1QL1,GPR75,GPM6B,PCLO,ELOVL5,ITIH2,MX1,MYO6,CDK18,PPP2R2B,CNNM2,ZCWPW1,RFX3,ROM1,EMID1,SH3BP2,ASAP3,RPH3A,SLC11A1,SNAP25,FAIM2,TNIK,CHST8,TRPC1,RPRM,VSNL1,DPF3" Drug 6394_DN C75; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.60E-07 7.83E-03 6.02E-06 6.85E-05 59 193 "AP2A2,NME5,PLA2G6,C1QTNF3,SYT13,MRTFA,CDC42BPA,APAF1,FAM131A,SPTBN4,CDK13,ALDH4A1,GYG2,LDLRAD4,CALB1,GPR37L1,ADGRG1,RAB28,PICK1,WHRN,SIPA1L1,RASSF2,MFAP3L,DTNA,HIPK3,ING4,TNK2,DMTN,LRRC23,F3,ANKFY1,USP21,TRAF3IP2,ELOVL5,INPP1,JAK2,MAP2,BCO1,MYT1,NOS1,LRP12,PLPPR1,PTHLH,RAD51D,RFX2,RGS10,SELL,STUM,BTBD7,LIMCH1,DOP1A,KAZN,PCDHGA10,HEY2,CLIP2,REEP1,SCG2,KCNAB1,SSPN" Drug 7364_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.60E-07 7.83E-03 6.02E-06 6.85E-05 59 193 "APC,APLP1,PPFIA3,APP,MYRF,HIP1R,SOCS6,CLCN4,HOMER3,TBC1D5,SIRPA,KLHL3,DLG3,CDON,DTNA,FEM1B,SORBS3,TNK2,EML1,F3,EFEMP1,ZNF589,CINP,DLL3,GAD1,SEPT9,HAS2,KHK,NUMA1,ODF2,PDE1C,PDE4A,KCTD15,MBOAT7,MAPK7,PTHLH,RIPOR1,RGS3,RGS10,KIF16B,ANKRD6,SCMH1,SMARCC2,IFT122,NMNAT2,DBNDD2,WSCD1,SZT2,SYNE1,TNS2,TIAM1,TK2,TRPC1,FAM155A,LMF1,PMEPA1,PRDM10,SMIM8,PHTF2" Drug 4846_DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.60E-07 7.83E-03 6.02E-06 6.85E-05 59 193 "ABHD6,AK2,ARNTL,ARRB2,NUMB,MPDZ,SCAPER,MTMR2,CA12,CAMK2G,MAP7,KYAT1,KRIT1,AKAP7,SLC4A7,DCAF8,KIAA0586,DMPK,RCAN1,EIF5,ENO2,EPB41L2,F3,AMOTL2,FAM49B,INPP5K,SRCAP,SLC2A6,INPP5B,KCNH2,MMP16,PDE3B,RETREG1,PLEC,PPP2R2B,PPP5C,PRPH,PTK2,SH3BP2,ITSN1,FAM214B,ELMO2,TTC17,FNBP1,TEX2,TTBK2,TACC1,IQCE,TCF7L2,SLC44A1,TK2,KAT6B,UBE3A,NSD2,NDRG4,SNX27,C12orf4,KAT6A,PHTF2" Drug 6846_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.60E-07 7.83E-03 6.02E-06 6.85E-05 59 193 "NME5,PLA2G6,GAS7,SLC4A4,ATP6V0A1,SYNJ1,SCAPER,USP2,ARHGEF1,PLAA,FADS2,PICK1,FAM149A,AKAP6,CPS1,PDE4DIP,CTIF,SPOCK3,RABGAP1L,CDON,EDN1,FRY,MBNL2,ELAVL3,ACSL4,ZNF589,PDLIM5,RUNDC3A,GLYR1,RAB30,GPER1,HNMT,ICA1,KCNMA1,PDE4A,EPN1,CDIP1,SAMD9,PTAFR,TCP11L1,SCN2B,ASAP3,DOCK10,FNDC3A,SLC14A1,KDM4B,PDZD2,SOX2,SPART,MAPK8IP3,SYN2,POPDC3,KAZN,TRIM2,TNS2,UCHL1,VIPR2,KCNK12,SENP7" Drug CID000000888 magnesium Stitch 1.66E-07 8.15E-03 6.26E-06 7.12E-05 277 1326 "ACTN1,METAP1D,NDRG2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,NME5,AK2,ALAD,ALK,MRTFA,AMPD2,PHF12,ANXA7,DGKZ,GPAM,DGKD,NT5C3B,APP,PDXK,ARHGDIA,DNAH17,DYNLL1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,KIF1A,BCHE,RGS9,FUBP1,CACNA2D1,DIRAS1,CALM1,ARHGEF25,KYAT1,CCK,KRIT1,CCNT1,AIFM1,ENTPD2,ENTPD6,DGKI,LRBA,CDC42,COPB2,CHM,CNOT8,TAOK2,RAB28,MYL6B,RAB26,COL4A5,GAL3ST1,CPS1,ENTPD4,CS,CSNK1E,CSNK1G3,VCAN,DGKB,DGKG,DNAL1,COPS7A,AK5,CHRDL1,EXOG,GRIN3A,DNM1,DNAH9,DPYSL2,DTNB,FARSB,DNM1L,AASDH,EDN1,EGFR,HSD17B14,TUBD1,ENO2,GPHN,RAB9B,ERCC2,RASL12,ADGRV1,F3,PTK2B,TUBB3,TUBB4A,FDFT1,POLR1B,ACTL6B,FGFR1,FGFR3,CAP2,FOXM1,AK8,TPK1,ATP2C1,FYN,MTHFD2,ACSS1,GCK,TUBA8,RND1,HPGDS,RAB30,GLUL,POLL,KCNMB4,GNAL,TUBA1C,TPPP,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM5,GSN,LINGO1,GUCY1A2,GUCY1B1,DDX19B,HMGCR,HSP90AA1,IDH3A,IDH3B,MYLK2,INPP1,TUBB2B,ITGAM,ITPKB,KCND2,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNMA1,KCNN2,LAMA2,LIG4,MAG,MAT2A,MATK,PPM1L,MMP16,MMP17,MTR,MYO5A,MYO7A,NBL1,NF1,NME4,NOS1,NPY,NPR2,NUCB1,OGDH,OGG1,OMG,OPRL1,P2RX7,PC,PDE2A,PDE3B,PDE4B,PDE4D,PDE1B,ENPP2,PFKFB2,PFKFB3,PFKFB4,PFKP,ABCB1,PHKG1,PIK3C2A,PIK3R1,PKM,PLCB2,PLEC,PMS2,POLR2F,PPM1B,PTPA,PPP3CA,PPP3CC,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK10,KLK6,CNNM2,PSMA6,LAMA1,PTK2,PTPRB,PEX5,QDPR,RAB5B,RAD51D,RIT2,RNASE1,RNH1,NEK11,RPL15,RYR1,RYR3,MAPK12,SARS,SMPD3,CASC3,SLA,RPH3A,SLC11A1,SLCO1A2,SNAP25,SNCA,NMNAT2,ADHFE1,JMJD6,ABCC8,NUDT10,NEU4,SLC19A3,DICER1,TK2,ICAM5,ACTR6,TNNT1,CABIN1,TPM1,NPL,TPM2,TPM3,TPM4,SMUG1,TRH,NEIL2,TRPC1,TRPC3,TUBB2A,TUBB1,WRN,SLC26A10,SPHK2,ZBTB16,DPYSL5,PLPPR5,WNK1,PRTFDC1,TUBA1A,GAL3ST3,HRASLS,DNAH10,RTN4,NUP214" Drug CID000001222 alpha-methyl-4-carboxyphenylglycine Stitch 1.67E-07 8.17E-03 6.27E-06 7.13E-05 18 32 "B3GAT1,INPP5K,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug CID000004938 propentofylline Stitch 1.67E-07 8.17E-03 6.27E-06 7.13E-05 18 32 "ADORA1,ADORA2A,ADORA3,APLP1,APP,ALDH7A1,BCHE,HAPLN1,GDA,DNM2,EPB41,GFAP,ITGAM,SLC1A2,SLC1A3,AHCYL2,SMUG1,VIPR2" Drug CID000005722 zaprinast Stitch 1.70E-07 8.35E-03 6.40E-06 7.28E-05 47 141 "ADCY5,ADCY6,ADCY8,ADD3,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,ABCD2,ARSE,PDE8B,ALDH7A1,RGS9,CALM1,KRIT1,LRBA,NUMBL,CHGB,ABCC5,EDN1,CALCRL,PDLIM5,PPARGC1A,GRIK1,GUCY1A2,GUCY1B1,HSP90AA1,KCNA6,NEUROD2,NOS1,NPPA,NPR2,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,RYR1,RYR3,SIRT1" Drug 3084_UP Clioquinol [130-26-7]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.75E-07 8.59E-03 6.40E-06 7.29E-05 58 189 "SYN3,BEGAIN,BIN1,FAM131A,PRX,PDXK,PLA2G4C,PDE8B,MPDZ,CACNA1I,CREM,PDE4DIP,CTNND1,EDRF1,ARHGAP32,KIAA0513,DLG4,RCAN1,CELSR3,GFER,PCLO,SLC2A6,HRH3,KIF5C,MAP4,MGAT3,MT1M,MX1,NAP1L2,NTRK2,OPRL1,CCSER2,MTRF1L,RELN,PTPRN2,RIPOR1,PID1,RAD52,ZFHX4,PAQR6,SH3BGR,SLC6A8,SHANK2,SNAP25,ARHGAP26,SPTAN1,DDN,PSD3,TEX15,TNS1,LILRA4,TRPC1,FLRT2,VGF,CLIP2,SLC13A3,SLC17A7,PCBP4" Drug 6088_UP Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "RALGAPA1,ADCY6,ADORA3,PLA2G6,ALK,BIN1,N4BP2L1,CACNA1I,CDO1,GPR37L1,SULT4A1,CPS1,ARHGEF10,RASSF2,EDNRB,EFNB3,ELAVL2,IGSF6,F5,FYN,NEU3,SRCAP,RUNDC3A,GNAO1,PRUNE2,GPM6A,ADAMTS13,ATXN2L,C2orf72,KCND3,KHK,MGAT3,KITLG,AFDN,DDX25,NOVA1,NTRK3,PCDHGC3,CDK18,PDE1C,LRP12,GDPD2,PTAFR,RFX2,RGS12,KCTD17,ROM1,TMEM206,SYNDIG1,NTNG1,SLC11A1,ZC3H13,BEX1,CLSTN2,CUX2,DNAH7,DAAM2,TMPRSS5,CA10,MVB12B" Drug 2286_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADD2,SYT13,AMH,GAS7,MARK4,ASTN1,N4BP2L1,ADGRB2,RGS11,ZFYVE9,CNN3,TCEAL2,CRMP1,CTIF,TMCC2,DYRK1A,EDN1,EFNB3,ING4,APC2,DLC1,ZNF589,FGFR1,OGA,LYVE1,RND1,GPER1,GPR37,NR3C1,SYNPO,TJAP1,MYCN,NEUROD1,CDK14,MTRF1L,LRP12,NECAB2,PRKAR1B,PRKCB,SNRK,PTAFR,PLPPR1,FAT4,RNASE1,MYH14,SEMA6D,ASAP3,PKNOX2,SNAP25,EMC1,HECW1,SPTB,NPAS3,MAPK8IP3,DMXL2,R3HDM1,SEZ6L,VSNL1,NT5M,SLC17A7" Drug 2387_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "MTUS1,BEGAIN,BIN1,CDC42BPA,ANK3,APAF1,APC,NCOA1,ALDH4A1,KSR1,BMP7,SYNJ1,CACNA2D1,CD38,CHN2,ZFYVE9,HOMER3,COL4A5,PPP1R16B,CTNND1,NOS1AP,PHYHIP,CTIF,DLG3,ST8SIA3,EIF4G2,LRRC23,RASGRP2,CDKL3,FHL1,GPR153,GRIN1,TJAP1,IL6R,KCNF1,MAPT,CD200,NFYA,PLEC,PTPA,PTK2,ASAP3,PEX26,EPN2,SLC20A2,ZCCHC24,SOX15,THSD1,SS18,PLCB1,PDLIM2,TBL1X,RPGRIP1L,CRTC1,ATP13A2,KCTD2,RBFOX2,TRPC3,FLRT2,LAT2" Drug 4594_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "SLC12A5,ADGRF5,C1QTNF3,APC,DNAH17,PTCH2,ALDH4A1,ADAM23,KSR1,BMPR1B,FUBP1,MTMR3,CACNA1G,RUNX1T1,SCARB1,SOCS6,CHRNB2,RAB33A,ABCG2,CREM,CTNND2,PLPPR4,HIPK3,ING4,ZNF549,ETV1,KIAA1109,FGFR1,GNG4,GRIK5,GRM8,HLF,IL6ST,JAK2,KCNF1,LIG4,VWA5A,MOBP,NEUROD1,NPTX1,P2RX7,PDE4D,MINDY2,PPP2R2B,MAPK8,RAB3IL1,FBXW7,SCN2A,SLC6A9,ARHGEF40,KDM4C,BEX1,ACSBG1,SLC44A1,TLR4,TPM3,REEP1,NT5M,KCNAB1,RNF146" Drug 4841_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,AMPH,BIN1,ANK1,CNTNAP1,CADM3,ADAM23,CFLAR,KSR1,CACNA1I,LDLRAD4,NEURL1,CDH8,AKAP7,IFFO1,NECTIN3,SUSD5,CTH,RIMS2,NOS1AP,DCT,EGFR,EFS,FGFR3,NR3C1,GRM1,TJAP1,ITIH2,KCNJ3,KIT,LIG4,TAGLN3,DDX25,NEFM,NOS1,PDE1C,PDE4A,PFKFB2,EPN1,PRKAR1B,SYNDIG1,ZFP30,SLC6A9,CCDC88A,KDM4B,ATP10B,INKA2,SYT11,DMXL2,PCDHGA10,DOCK9,PCDHA5,DICER1,THBS4,HEY2,R3HDM1,VAV2,LAT2,TRIM9,WNK1" Drug 4413_UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,ANK1,CDK13,ATP1A3,CACNA1D,CACNA2D1,USP2,SLC24A2,COL9A3,HAPLN1,NCOR2,CSF1,TENM4,MICAL2,CNTNAP2,DBT,KLHL3,DRP2,DTNB,C3orf18,LRRC17,RASGRP2,APC2,HPCAL4,FLNC,RASL10A,TBR1,GAB1,GCNT2,GPR162,ADAMTS13,GRM7,CELF3,ITIH2,KCND3,KIFC3,LMO1,VWA5A,MMP17,ADAM22,NPTX2,SNTG1,GPR85,SNRK,PTX3,RPS20,SEMA6D,SATB1,RASA3,SLC6A8,SLN,CLSTN2,INKA2,FAM189A1,TNS1,SEZ6L,XRCC4,KCNAB1,ITM2C,HRASLS" Drug 2531_UP Butamben [94-25-7]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NR0B1,C1QTNF3,APAF1,APBB2,APP,CASK,ALDH4A1,MAP7,CDC42,CLGN,B4GALT6,COL9A2,ARHGEF10,DAPK3,GSDME,CNNM1,SIDT2,MBNL2,ING4,TNK2,EIF1,COQ7,STX2,FER,SCARA3,GAB1,SIGLEC8,INPP5K,RND1,NCKAP1L,ATXN2L,SCRG1,MDM4,NDUFA5,NINJ2,P2RY1,PDE4D,PPARA,PPP5C,MAPK7,MAPK10,RIPOR1,MYH14,TCP11L1,MAP6D1,SEC14L1,RASA3,SH3BGR,NTNG1,EPN2,SLC11A1,SHANK2,SPTAN1,MAPK8IP3,TCF7L2,AHCYL2,TMOD1,TRIO,TRPS1,SENP7" Drug 3753_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "SYN3,ADORA1,ADORA3,DDX3Y,CACNA2D1,SYNGR3,LARGE1,CDO1,JAM2,SLC22A6,COL9A3,SNCAIP,CNTNAP2,TOX,SPOCK2,DBT,ARNT2,ATN1,DYRK1A,EFNA3,PLXNC1,ING4,CPLX2,SRCAP,GFRA1,RUNDC3A,RND1,GNAL,GNG3,GRIN1,IL1RAPL1,C2orf72,KCNJ4,KCNN1,KCNQ3,MEF2C,ADAM22,SAMD14,NPTX1,CDK18,PDGFRA,GPR85,PLP1,PLXNB1,CEP41,PTN,PTPRH,PTPRO,RAD52,RASGRF1,ZNF821,CPEB3,PREX2,SLC15A2,DOP1A,SYT11,TRO,FLRT2,VAV2,KCNAB1" Drug 1468_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "APBA2,BCAS1,PPP4R4,ASPH,ALDH4A1,CFLAR,ST3GAL5,SCAPER,RUNX1T1,SEPT7,ASIC3,CLU,DNAJB5,NECTIN3,FAM169A,CTIF,KBTBD11,EDNRA,F3,FOXG1,GABRA5,CNTRL,C2orf72,TJAP1,KCNH2,NEK1,NPY,NUMA1,PENK,MAPK7,MAPK8,CNNM2,RGS12,ASAP3,FBXO11,SLC1A7,PPP4R3A,SLC9A5,LIMCH1,RBM34,ERC1,SPART,PHLDB1,PLCB1,ATP11A,FBXW11,TBL1X,CRTC1,HIF3A,DNAH7,DICER1,CHST8,HEY1,TLR4,TMOD1,CABIN1,WIPF1,LAT2,PRDM2,EPM2A" Drug 3426_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,MRTFA,CDC42BPA,APBB2,APC,ALDH4A1,SLC4A4,MTMR2,BAIAP3,CBFA2T2,NMT2,SULT4A1,NOS1AP,CNIH3,RUSC2,HSD17B14,ERCC2,IQCG,ALDH1L1,TDRKH,GPR19,STON1,NR3C1,IL6ST,INPP1,KCNH2,KCNN1,LAMA2,MATK,MIA2,SLC11A2,NUMA1,PLCD1,PLP1,PPARA,ELOVL2,ZSCAN32,RGS3,SUPT20H,RASA3,ZCCHC24,ZBTB43,MAPK8IP3,MLC1,MCF2L,TBCEL,IQCE,WSCD1,SIN3B,TCF7,SZT2,PCDHA6,TMOD1,ZKSCAN5,VIPR2,MICAL1,LMF1,KCNAB1,MPPE1,SSPN" Drug 2792_UP Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADORA2A,ALCAM,KCNAB2,PPFIA3,CDK13,ADAM15,LDLRAD4,CACNB2,SLC16A4,CBFA2T2,SRSF11,AKAP7,TENM4,CNTNAP2,MBNL2,HSD17B14,EFS,F3,ZNF589,EFCAB2,GAD2,MSL3,GRIN1,NR3C1,HAS2,HLF,ICA1,TJAP1,KCNK1,KIT,MMP16,ADAM22,BCO1,NF1,CDK18,PDE1C,PPP5C,PRKAR1B,SIDT1,CCDC40,RAD52,RGS12,PPP1R9A,ASAP3,CCDC88A,SLC11A1,SHANK2,EMC1,KIAA1107,PSD3,PCDHA5,DICER1,TRIO,TRO,REEP1,TFIP11,SYNC,NT5M,ITM2C,ST7" Drug 6681_DN Etoposide [33419-42-0]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "TRMT9B,AMT,CDC42BPA,APAF1,SEMA4G,ST3GAL5,SCARB1,CDC27,CACNA2D2,NRXN3,NIPBL,PICK1,CSF1,ARHGEF4,RIMS2,PLXNC1,EIF5,TNK2,ZNF391,ETV1,EFEMP1,HPCAL4,SEMA4D,DCTN2,ERAP1,HLF,LIFR,VWA5A,MPP2,LYRM9,NDP,NOS1,NOVA2,PBX1,PDE4D,GPSM2,PLXNB1,PROX1,FAT4,RGS10,KCTD17,SUGCT,ZNF821,ZFP30,ASAP3,FHOD3,DZIP1,PREX2,IQSEC2,DDN,TBCEL,IQCE,ZEB1,SYNE1,DOCK9,TNS1,TRIO,XRCC4,REEP1,NAV3" Drug 5487_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ABR,ABHD6,ACTN2,KIDINS220,MRTFA,APBB2,NCOA1,KIF1A,BCL2L2,BCL7A,ST3GAL5,SYNGR3,ZMYM4,RAB28,ZFYVE9,BAG4,CHD1L,FAM169A,DCAF8,ZNF337,GIT2,SMG7,PARD6A,RABGAP1L,ATN1,EDNRA,CNNM1,SIDT2,SUGP2,SORBS3,PLEKHO1,STX2,POLL,GNG4,PRRC2B,GPR37,IL6R,NFYA,PDE3B,PDE4B,SEC61A2,FOXRED2,SUPT20H,FAM214B,SPATA7,CEP68,PHLDB1,STX1A,TBL1X,ZNF34,CDK20,SMUG1,PLPPR2,VLDLR,ZNF74,HPS4,URM1,ST7,KAT6A,SSPN" Drug 7508_DN CP-863187 [668981-07-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,OGT,APC,ALDH4A1,SLC4A4,N4BP2L1,SYNJ2,BTRC,CA4,ARHGEF1,CDH10,CRLF1,VAX2,QKI,IQCK,SH2B1,CTIF,GIT2,MFAP3L,ATN1,DTNA,DTNB,HIPK3,FEM1B,EFNA3,EFNB3,EIF5,SPEG,ZIC4,FER,SCARA3,PDLIM5,FAM49B,SEPT9,ARFIP1,EML4,HNMT,ITPKA,KCNJ3,L1CAM,MMP16,ADAM22,NF1,CCSER2,EPN1,MAPK7,ZCWPW1,SBF1,ASAP3,SLC1A2,ZNF365,SLN,IZUMO4,IQSEC2,CDK20,TRPC1,SSBP2,HIRA,ZBTB14,GAN" Drug 3010_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "C1QTNF1,MRTFA,CDC42BPA,APAF1,APBB2,GYG2,THSD7A,BRSK2,INA,CACNA2D2,CBARP,CHGB,CLCN4,RAB26,SIPA1L1,CNTNAP2,USP6NL,DAPK1,SPOCK2,DNAJC6,MRNIP,CALCRL,PRELID3A,CSPG5,GABRA1,GABRA2,GALC,ADAM28,GNAO1,PCLO,GRIA1,CACFD1,ATXN2L,SYNPO,SCIN,KCNC1,KIT,MBNL1,LYRM9,NCAM1,NEFM,CAMKV,CNNM2,GDPD2,SLC6A15,MYH14,PNMA8A,KCNIP2,FAM214B,SOX10,HECW1,ST5,TACR1,TGFBR3,TMOD1,SSBP2,VSNL1,KLC2,ADAMTS9,KCNAB1" Drug 2228_DN Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,KIDINS220,LTBP4,PLA2G4C,MARK4,ATM,ATP6V0A1,CFLAR,SYNJ2,CACNA1A,CDH10,ARHGAP33,ZFYVE9,PICK1,CSF1,CSF1R,SEC14L5,DCAF8,DAPK3,CDON,STX2,ZNF589,FGFR1,CAMSAP1,FHL1,EFCAB2,PDLIM5,FAM49B,CNTRL,GRIK5,GSN,GSTM5,TJAP1,INPP1,JAK2,ADAM22,SLC11A2,PDE3B,MAPK7,GON4L,PTHLH,PEX5,EMID1,FAM192A,SYBU,SLC6A8,BTBD7,WDTC1,ARHGAP26,THSD1,PLCB1,KAZN,RPGRIP1L,TNS2,CABIN1,RUNDC3B,SPHK2,SYNC,SMIM8,GAN" Drug 5865_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADCY6,AGT,NME5,LTBP4,TRMT9B,MYRF,IL33,STOML1,CSF1R,SPOCK2,BRINP1,ATN1,RCAN1,DTNA,EDIL3,ST8SIA3,AASS,TENM1,RRAGB,FOXG1,C1orf61,DCTN2,GALC,SEPT9,GLI2,MSL3,GPR19,LPAR4,ICA1,KCNMA1,KCNQ3,LAMA2,VWA5A,MT1M,NNAT,NOVA1,NPPA,SNTG1,PDE2A,CAMKV,PRKAR1B,RGS12,KCNIP1,SAFB,IL17RB,DZIP1,SLC4A3,SLC1A7,SLC11A1,SLC15A2,RBM34,SOX2,DOK5,ERC1,SEMA4A,SMG6,TCF4,TMEM121,REEP1,FZD3" Drug 4353_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC2,ADORA1,NR0B1,ALK,CDC42BPA,APOC1,ARHGDIG,ATP2B2,ARHGEF2,CLTB,SULT4A1,CRMP1,SUSD5,ATRNL1,DCAF4,RIMS3,DGKG,CTIF,ATN1,DUSP9,DYRK1A,ERBB4,SPEG,GABRA1,DENND2A,GAD1,ALDH1L1,GPM6A,GPER1,IL1RAPL1,SOX21,ATXN2L,KCND3,LIFR,LMO1,LSS,MAP4,MMP17,NEFM,NTRK3,CDK18,PGAM2,CEP41,PTPRO,RFX2,RGS4,RORB,SH3BP2,ASAP3,CNKSR2,SLC11A1,PDZD2,PEG10,ARHGAP26,ATP10B,RGL1,VAMP1,R3HDM1,SLC30A3,ADAMTS9" Drug 6196_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASPHD1,KIDINS220,BIN1,SEMA7A,APAF1,NRP2,CA4,CDH10,STOML1,SULT4A1,TCEAL2,MICAL2,PDE4DIP,DCT,KLHL3,ATN1,EFNA2,SORBS3,HSD17B14,ERBB2,F5,IQCG,NEU3,STON1,PCLO,TPPP,KLF12,KCNA1,LMO1,MAP2,MDFI,MGAT3,MPP2,MYH6,MYL3,OLR1,TREM2,PCDHGC3,PRPH,ACSS3,RGS12,SCG5,EPN2,SMTN,KDM4B,PEG10,SS18,INKA2,MAPK8IP3,TCF7L2,TRIM2,PCDHA5,ATP13A2,GPR161,TRIO,VSNL1,ZIC3,PMEPA1,PRDM2,FAM13C" Drug 2521_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ALK,PPFIA2,CNTNAP1,APOC1,SHROOM2,ALDH4A1,ATP6V0A1,BMP7,CA12,CDO1,CHRNB2,RAB33A,ZFYVE9,SULT4A1,CNR1,CNTFR,WHRN,MYRIP,CREM,SNPH,GSDME,DLG3,HIPK3,SIDT2,TNK2,C3orf18,F5,DLC1,FHL1,FOXG1,NBEA,RUNDC3A,ITIH2,KCNJ4,NEFM,NTRK2,PCDH9,PDE1C,PDGFRA,STRN3,MAPK7,MAPK10,ZMAT4,KCNIP2,PEX26,SMTN,SLCO1A2,FAIM2,DOK5,SEPT8,ACSBG1,SYP,SLC19A3,TEK,ICAM5,PRMT8,REEP1,SLC17A7,KCNAB1,PAK5" Drug 316_UP flufenamic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "KDM5D,ALK,BIN1,ANK1,GAS7,DNAH17,GYG2,BAIAP3,BTRC,CACNA1A,CACNA1E,CH25H,CHGA,JAM2,STOML1,TJP2,OSBPL3,PDE4DIP,HDAC9,DAPK1,GIT2,HEPH,ING4,HSD17B14,STX2,CDKL3,BAIAP2,NSG1,GAB1,BRD8,MCHR1,PTPRT,NCKAP1L,KIFC3,MBP,MYBPC1,MYH7,MYL3,NPY,NPTX1,OPCML,CAMKV,FXYD1,HYDIN,PRODH,ZCWPW1,RFX2,RGS12,FNDC3A,SLC8A1,RIMS1,NMNAT2,SYN1,TCF4,DNAH7,THRA,SEZ6L,PRMT8,VIPR2,SLC13A3" Drug 5443_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,ADCY6,AP2A2,BIN1,ANK1,APC,CACNA1D,THSD7A,ADGRG1,SLC24A2,SULT4A1,SLC4A7,CPS1,CSF1,CNTNAP2,DCAF4,INTS1,HS3ST2,ATN1,FRY,EFNB3,TNK2,TUBB4A,HPCAL4,FOXF2,DLL3,GATM,GFER,GLS,PRUNE2,PCLO,NR3C1,HAS2,ICA1,MAP4,MATN3,KITLG,MOBP,ADAM22,NTRK3,PCDH9,PFKFB2,PTHLH,PTPRO,ENOX1,FAM214B,TNIK,KIF21B,HECW1,PEG10,ZNF423,ARC,TCF4,HEY1,TRPM2,UCHL1,ZIC3,CA10,KCNAB1,ITM2C" Drug 4525_UP Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "AGT,MRTFA,EPB41L5,PPP4R4,ARHGDIG,ALDH7A1,ADGRB2,CACNA1G,IFFO1,CPS1,RGS6,VCAN,SPOCK3,CDON,ATN1,COQ7,F5,ZNF589,FGF1,SEMA4D,AFF2,GAB1,PRUNE2,GRIK5,ICA1,KCNMA1,KIF5C,MGAT3,AFDN,NCAM2,NEUROD1,PDE3B,RASGRF1,KHDRBS2,RGS12,PNMA8A,EMID1,RTN1,FOXRED2,RASA3,ASAP3,PREX2,PKNOX2,SNCA,TSNAXIP1,VAMP1,KAZN,ADGRL3,SZT2,TEX15,SPX,ICAM5,TLL2,TMOD1,R3HDM1,SEZ6L,SPHK2,KCNAB1,FAM13C,NUP214" Drug 3824_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ACTN2,MRTFA,ARRB2,ZSCAN18,ATP6V0A1,ADAM23,BMP7,SCAPER,CFAP410,SYNGR3,NEURL1,CRLF1,CHI3L2,NDST3,AATK,RGS6,MAGI2,SMG7,SRGAP3,DLG2,DLG4,ATN1,ABCC9,PLXNC1,LRRC17,ATP8A1,FOXG1,FOLR2,PDLIM5,ERGIC3,DISC1,GFER,RND1,GRM7,PADI2,ICA1,IRF8,IGSF1,VWA5A,SMAD1,KITLG,MSI1,MYT1,PDE3B,GPR85,PDZRN4,MED1,PROX1,RAB3IL1,RASGRF1,RET,CCDC102B,RTN1,SEMA6D,SH3BP2,CNKSR2,SLA,SPTAN1,HIRA,VIPR2" Drug 6517_UP Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "PLA2G6,GAS7,CFLAR,SYNJ1,SYNJ2,CAMK2G,PLEKHB1,TAOK2,ZFYVE9,TPP1,HOMER3,AKAP7,MAML1,BRINP1,HP1BP3,DMPK,DTNA,EDNRA,EFNA3,EFNB3,FAM13A,MBNL2,FER,GAB1,ERAP1,ALDH1L1,GPER1,GRB10,NR3C1,GSTM5,SHISAL1,KCNJ3,KCNN1,LIG4,MEF2C,MMP16,MSI1,NEUROD1,CNOT4,RETREG1,MTRF1L,MAPK8,RELN,KCTD17,GSTCD,SNAP25,SNCA,PLCB1,ZEB1,TRIM2,TMOD1,TRPM2,TTPA,VIPR2,LAT2,NSD2,XRCC4,SCG2,PHTF2,JPH3" Drug 3879_UP Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "RALGAPA1,AGT,ALCAM,TRMT9B,APC,GAS7,ATM,CADM3,ADAM23,CDH18,ARHGEF6,CNR1,NCOR2,TENM4,DNAH9,DYNC1I1,FAM13A,CEND1,ATP8A1,OLFM1,FGFR1,CAMKK2,GFER,PRUNE2,GPER1,HTR2A,IRF8,KCNB1,KCNN2,L1CAM,SMAD1,MMP16,ADAM22,ZNF862,NF1,OPRL1,RETREG1,NECAB2,CEP41,PKN2,RPS6KA2,EMID1,ZNF821,SH3BP2,ASAP3,FAIM2,TROVE2,SAMSN1,MAPK8IP3,TBL1X,CRTC1,TRIO,TRPC1,HIRA,SLC30A3,EMSY,PRDM2,STMN4,SLC17A7,DPF3" Drug 2467_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ACTN2,SRPX,AMH,BIN1,OGT,PRX,CDO1,CHRNA4,CLCN4,SLC24A2,ABCG1,CRYM,ZFYVE16,MAGI2,SEZ6L2,FAM13A,PLXNC1,RASGRP2,MTSS1L,FGFR1,FOXG1,AGAP2,GAB1,GPR75,PCSK1N,GPR22,HRH3,KCNJ5,KIT,MAPT,MDFI,MMP16,MYH7,NAP1L2,NEUROD1,NRCAM,PCSK5,PDE4D,PGAM2,POU3F2,WDR25,PTAFR,PTPN13,MARCH1,SALL1,EPN2,PKNOX2,SPTB,PLCB1,SYT5,TACR1,MTCL1,WWC1,ATP13A2,TPM1,UBE3A,ZBTB38,STMN4,SCG2,KCNAB1" Drug 3342_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "KIDINS220,NME5,SEMA6A,GAS7,BRINP2,N4BP2L1,CACNA2D1,HAP1,ARHGEF2,CHI3L2,CHN2,ZFYVE9,NRG2,VCAN,GREB1,SNPH,RIMS3,DRD1,ST8SIA3,EDN1,MBNL2,CDHR1,FAM198B,DLC1,FHL1,GNAS,GPR37,GRM1,IL6ST,LAMA2,MAPT,MOBP,BCO1,MSR1,TAGLN3,NF1,PDE4B,PLTP,PDZRN4,SAMD9,SNRK,PTHLH,ZMAT4,RGS12,KCNIP2,FNDC3A,CNKSR2,EPN2,SORCS3,ZC3H13,ARHGAP26,ATP10B,SSTR2,DMXL2,GPR161,TRPM2,VAV2,WIPF1,DNALI1,SEMA3B" Drug 2488_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADD2,AGT,CNTNAP1,ARHGDIG,CADM3,KSR1,EPS15L1,SULT4A1,RAB26,COL9A3,CREM,DAPK3,C2CD2L,MAGI2,SMG7,RASGRP2,MTSS1L,KIAA1109,FOXG1,CAMKK2,GPR75,GRK4,PCLO,GRIK2,GRM7,GUCY1A2,RASSF8,KCND3,KIFC3,MMP16,NEFM,PDE2A,PHKG1,CCSER2,PLP1,PRKAR1B,MAPK8,PROX1,RFX2,RGS10,PRR5L,KCNIP1,RYR1,SNCA,ARHGAP26,SPTB,DDN,NFASC,MAPK8IP3,PLCB1,TAL1,DOCK9,TK2,TMOD1,KAT6B,TRPC1,FLRT2,SLC17A7,KAT6A,SSPN" Drug 4251_UP Antipyrine [60-80-0]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADORA2A,NME5,PKP4,APBB1,ATP2B2,N4BP2L1,ATP6V0A1,BMP7,SYNJ2,HAP1,HIP1R,RUNX1T1,KCNAB3,FOXN3,CHI3L2,SEC31B,RGS6,PLCH2,PDE4DIP,KIAA0513,DMPK,DSCAM,DYRK1A,IRAK4,TENM1,PTK2B,ATP8A1,DCTN2,GAB1,ELOVL5,IL6ST,KIF5A,KIT,LMO1,SMAD1,MAP2,ADAM22,MSR1,TAGLN3,NPTX1,PCBP3,NRCAM,PTAFR,BEND5,RGS4,SEMA6D,FBXO11,ST6GAL1,OGDHL,SNCA,PDZRN3,HECW1,ZC3H13,SPTB,MCF2L,ADGRL3,TPM1,TUBB1,UBE3A,MVB12B" Drug 2463_DN "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,MTUS1,C1QTNF3,BIN1,MAP4K3,APC,APOC1,ARRB1,ASPH,NCOA1,BACH1,CACNB2,FOXN3,IQCK,CSNK1E,CTNND1,EDRF1,TSPAN5,HIPK3,EIF1,LRRC23,NCALD,KIAA1109,IQCG,FYB1,ZMYND11,GLS,RAB40B,SMAD1,MDM4,ZNF862,NDUFA5,NEK1,NFYA,SLC11A2,PIK3R1,ST8SIA5,PTPRN2,RAD52,ZDHHC14,RNASEL,CARF,ZNF821,FAM102A,AMBRA1,PPP4R3A,SIRT2,SLC20A2,SS18,ATP11A,CAMSAP2,KIAA1107,DICER1,TMPO,TRPS1,UBTF,MAP3K12,PHTF2,TIGD6,SENP7" Drug 4099_DN Alprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASPHD1,AMH,GAS7,CDC14B,PDE8B,ATP1A3,NOL4,MYRF,BAIAP3,CACNA1A,BRSK2,ARHGAP33,LHX2,HOMER3,TCEAL2,NCOR2,TENM4,CNTNAP2,RIMS2,ATN1,PLXNC1,AASS,IRAK4,COQ7,MTSS1L,ZNF549,DLC1,KIAA1109,FGF1,SEMA4D,FLT1,CINP,ZNF44,GLRB,GPM6B,LPAR4,DIDO1,GRIK2,ADAM22,OPCML,PDE4D,RETREG1,SPATA6,PTPRB,RGS7,CCDC102B,NLGN1,DZIP1,SLC1A6,SCN3B,KDM4C,ACSBG1,PCDHGA10,R3HDM1,TRPC3,LAT2,ZIC3,REEP1,MAP3K12,NT5M" Drug 5473_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,ALK,BIN1,SEMA7A,ALDH7A1,BAIAP3,BTRC,CACNB2,SULT4A1,HP1BP3,SPOCK3,CDON,HIPK3,EFNA3,C3orf18,MTSS1L,STX2,CDHR1,ABCA8,FGFR1,MYOZ2,HPGDS,GLRB,NR3C1,HLF,IL6ST,KCNC1,KCNJ5,KCNMA1,MMP16,GIT1,ADAM22,P2RY1,SNTG1,PENK,DUSP26,SERPINI1,GDPD2,ACSM5,C1orf54,PRR5L,RYR3,FRMPD1,NLGN1,ABLIM3,SLA,RIMS1,SOX10,CAND2,CLSTN2,INKA2,RPGRIP1L,GPR161,TK2,R3HDM1,ZMYND8,LMF1,PRDM2,NAV2,EPM2A" Drug 6592_DN "16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG3,ANK3,EP400,PPFIA1,KCNAB2,APOC1,CDK10,ALDH4A1,RAB26,HDAC9,DPH1,ATN1,STX2,ANKMY1,FOXG1,NBEA,SYT17,USP19,HTATSF1,GPER1,RASSF8,INPP5B,LIFR,MAPT,MEF2C,MX1,ZNF862,NFIX,NPR2,CCSER2,GRAMD1C,CNNM2,SAMD9,BCAS3,PTCH1,PTPRN2,GAL3ST4,NEK11,FBXW7,RPS6KA2,MAPK12,SH3BP2,SLC14A1,SMARCD3,IQSEC2,SRPK2,POGZ,PLCB1,OBSL1,CHST8,TNS1,RBFOX2,CHST5,UBTF,PLPPR2,LAT2,KLC2,TRIM9,NT5M,MVB12B" Drug 3802_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "APAF1,ARRB1,BRINP2,CADM3,ATP6V0A1,ADGRB2,CACNA1I,MYRF,CFAP410,CD86,JAM2,TAOK2,TPP1,VAX2,NCOR2,TRAPPC9,DTNA,DTNB,ETV1,ATP8A1,SEMA4D,DISC1,RUNDC3A,GLYR1,GRM8,KCNJ5,KCNN1,KCNN2,VWA5A,KITLG,AFDN,MYL3,NF1,SLCO1C1,NPTX2,TREM2,PDE2A,PDE4D,GPR85,PURG,C19orf57,POU3F4,FSD1,LRRN3,PTAFR,RGS12,SNAP25,SOX10,LMO3,NXT2,MAPK8IP3,ACSBG1,SYT11,TMEM151B,TNFRSF1B,TPM1,TUBB1,LAT2,SPHK2,PARP6" Drug 5220_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "CDC42BPA,APBB2,DNAH17,KSR1,SYNJ1,SYNJ2,SCAPER,BTRC,CDC42,CDH2,FOXN3,SOCS6,NRXN1,ARHGEF6,TCEAL2,CREM,VCAN,SEC14L5,INTS1,TMCC2,KBTBD11,MBNL2,ING4,ELAVL3,RASGRP2,GAP43,SRCAP,RUNDC3A,GLYR1,RAB30,POLL,GRB10,GRIK5,ICA1,IFI16,IL6ST,KCNMA1,MAP2,ADAM22,MYL3,ZNF862,NF1,CDK18,LRP12,PTHLH,CCDC40,GAL3ST4,MYH14,FUZ,SMTN,KANSL3,SLN,STX1A,ARC,PCDHA5,TNS1,TRIO,LAT2,XRCC4,TIGD6" Drug 2158_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "NDRG2,ADD2,APAF1,APP,SEMA4G,ALDH4A1,FUBP1,CLDN10,NMT2,PICK1,MYRIP,RIPOR2,DBT,SGK2,EIF1,F5,KAT8,PDLIM5,CAMKK2,SIGLEC8,INPP5K,ALDH1L1,C1QL1,ZNF276,HPGDS,GPR19,GSN,PADI2,ICA1,L1CAM,MAP4,ZNF862,ODF2,OPCML,PDE4A,PFKFB2,PPP5C,DEF8,PTPRN2,SUSD4,RFX2,SLC1A7,SLC2A5,SMTN,BTBD7,PALLD,DOP1A,SPTB,TSPYL2,SEPT8,MCF2L,CAMSAP2,KCTD2,TNS1,TPM3,RUNDC3B,BEST1,LMF1,ETNPPL,PRDM10" Drug 2206_UP Finasteride [98319-26-7]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ABHD6,PLA2G6,SRPX,BIN1,CDK10,PDE8B,NCOA1,GYG2,BTRC,CFAP410,CA12,SYNGR3,CHN2,ZFYVE9,CLCN4,ARMC8,ABCG1,EDRF1,DAPK3,MFAP3L,TRAPPC9,DSCAM,EDNRA,MBNL2,SORBS3,PLEKHA1,C3orf18,F5,FGFR1,IQCG,ALDH1L1,GPR162,GFER,POLL,IL6ST,KHK,MBNL1,MID1,MOBP,NNAT,NPPA,P2RY1,PLCD1,PURG,PMP22,FSD1,KIRREL1,SHANK2,SLN,PALLD,TNIK,SPTB,PHLDB1,RPGRIP1L,TEX15,ATP13A2,KCTD2,SYNC,MAP3K12,SLC17A7" Drug 6726_DN Ioversol [87771-40-2]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,ARHGDIG,KIF1A,BTRC,CCNT1,ARHGEF1,SEPT7,WHRN,NRG2,CRMP1,CSF1R,VCAN,CNTNAP2,SIDT2,EFNB3,SORBS3,MRNIP,FYB1,SIGLEC8,INPP5K,USP19,LYVE1,COPS8,MSL3,GPD2,GPM6B,STON1,KCNN1,KIF5C,MAP4,MGAT3,NF1,NOVA1,SNTG1,EPN1,TNPO2,PRKAR1B,PRPH,PTPRN2,RAD52,RALGDS,RGS10,KIRREL1,NEK11,FOXRED2,DOCK10,MYH15,SOX2,TNIK,UNC5B,ARHGAP26,LHPP,TROVE2,RPGRIP1L,PCDHA5,THRA,TRIO,VGF,PRDM2,HPS4" Drug 5805_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,ADRA1D,TRMT9B,APC,ATP2B3,KSR1,BTK,CDK5R2,CDH8,CACNA2D2,ARHGAP22,RAB33A,CNTN1,ARMC8,WHRN,COL9A2,CRMP1,NCOR2,ARHGEF10,CTNND2,ARMCX2,ATN1,CORO2B,FGFR1,C1orf61,SYT17,DISC1,ALDH1L1,SPACA9,GRM7,SOX21,HSD17B1,KCNB1,KIFC3,TAGLN3,NKAIN1,PID1,ACSS3,RFX2,SEMA6D,SCN2A,STUM,DZIP1,SLA,PKNOX2,BTBD7,OGDHL,PDZRN3,KDM4B,EMC1,ATP10B,COBL,TACR1,TLR4,SEZ6L,WIPF1,REEP1,TFIP11,MAP3K12,KCNAB1" Drug 1529_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADORA1,MARK4,DDX3Y,ATM,ATP1A3,CFLAR,CFAP410,CACNA1D,CDH8,GPR37L1,RAB33A,PLAA,FADS2,QKI,SNCAIP,CNTNAP2,SPOCK2,DBT,MFAP3L,MAGI2,CDON,ATN1,STX2,KIAA1109,PDLIM5,GPR153,GABRA5,SRCAP,COPS8,GLS,GPM6A,KIFC3,VWA5A,TM6SF1,MIA2,AFDN,NPPA,PCBP3,PCSK2,PDE1C,PFKFB2,PACSIN1,MED1,VPS13C,RAD52,KCTD17,KCNIP1,RYR1,ITSN1,BCAN,SYBU,SLC22A4,SOX2,INKA2,EXOC7,TIAM1,TRIO,HIRA,SYNC,HPS4" Drug 1523_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ASIC1,AMPD3,BIN1,CDC42BPA,SEMA7A,APOC1,MARK4,CAPRIN2,NUMB,ALDH7A1,SCARB1,CHGA,AKAP6,CSF1R,ATRNL1,PYGO1,RIPOR2,RASSF2,SPOCK2,OPTN,EFNB3,BAIAP2,INPP5B,KCNMA1,KCNQ3,SMAD1,MAPT,MYCN,NEUROD1,NF1,NNAT,SLC11A2,PALM,PCDH9,PDE4D,PFKFB2,PIK3CD,LRP12,PRODH,ZSCAN32,CEP97,RFX2,ZFHX4,KCNIP1,SH3BP2,ZNF365,SLC8A2,SHANK2,SLN,ZCCHC24,ZNF423,TROVE2,MAPK8IP3,SYT5,TBCEL,SMG6,SZT2,HIF3A,TRIO,SCG2" Drug 5694_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "BBOX1,APBA2,GAS7,SGCE,CAST,CBFA2T2,SLC24A2,FADS2,CRYBB1,IPCEF1,MAGI2,ATN1,DTNB,C1orf61,NSG1,GABRA2,SRCAP,RUNDC3A,RND1,GLS,CACFD1,GRM8,ADAMTS6,KLF12,ICA1,IFI16,KCNJ5,KCNJ9,KPNA5,MATN3,MOBP,NOVA2,PCSK2,RETREG1,PLCD1,LRP12,PPARA,PTPRO,RAB3A,RGS7,TMEM206,SLC1A3,SLN,MYH15,LMO3,PHLDB1,AJAP1,VAMP1,PLCB1,TAL1,TCF4,DOCK9,HIF3A,TEX15,TMEM121,CHST5,UBE3A,SLC30A3,HRASLS,CAMK1G" Drug 6044_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "KIDINS220,C1QTNF1,ALK,BIN1,AMT,ANK1,APLP1,PLA2G4C,ASCL1,CCDC181,ATP2B2,FGF17,SLC16A4,NRXN1,ARHGEF6,CNTNAP2,DGKG,DTNB,DYRK1A,FRY,EGR3,ERBB4,CDHR1,CDKL3,ZNF589,B3GAT1,GCNT2,GFER,GNAL,PRUNE2,GRM8,HNMT,TJAP1,MID1,BCO1,TAGLN3,ZNF862,NEFH,PDE4D,PDZRN4,POU3F2,MINDY2,PPP5C,PKN2,FAM120C,RGS12,NUDT11,KCNIP1,SCNN1D,ASIC4,RASA3,SNAP25,KDM4B,ATP10B,ACSBG1,TCF4,PCDHGA10,CHST5,TRO,LAT2" Drug 1507_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "AP2A2,KCNAB2,APC,ATP6V0A1,SCAPER,RAB33A,NMT2,DNAJB5,CNTFR,CSF1R,GREB1,NOS1AP,ELMO1,MFAP3L,EFNB3,FAM13A,MBNL2,EIF4G2,C3orf18,EN2,DMTN,PTK2B,KIAA1109,FGFR1,AFF2,GAB1,MSL3,GPM6A,STON1,GRB10,GRIK2,NR3C1,IRF8,INPP1,KCNMA1,LMO2,SLCO1C1,NPR2,CDK18,PPARA,MAPK10,PRODH,RAB3A,KCTD17,SEC61A2,MYH14,ITSN1,BCAN,ARHGAP26,ZBTB43,PHLDB1,SYT5,TRIM2,TGFBR3,PDIA2,VAV2,WNK1,SLC17A7,MPPE1,RNF170" Drug 2891_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADRA1B,AP2A2,AMH,APLP1,APOC1,CACNA1I,BAIAP3,LDLRAD4,CFAP410,NEURL1,ARHGAP33,ADGRG1,TAOK2,ARHGEF6,ST18,SPOCK2,C2CD2L,DTNB,OPTN,EFNB3,ELN,C3orf18,HSD17B14,ERCC2,EXTL1,REEP2,AGAP2,FYN,SLC2A6,HNMT,ICA1,TJAP1,KCNJ5,KCNMA1,MEF2C,MSR1,NOVA2,NUMA1,GON4L,CCDC40,RAD52,SCN8A,DOCK10,SMTN,SLC11A1,BTBD7,PDZD2,KIF21B,ATP10B,SYT11,DNMBP,TBCEL,SMG6,WSCD1,DOCK9,PDIA2,GDPD5,SCG2,CAB39L,SSPN" Drug 4383_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "GAS7,APOC1,PLA2G4C,AZGP1,BAIAP3,CDK5R2,CAMK2B,HIP1R,CDH8,TMEM59L,CNN3,FAM149A,CABP1,ENTPD4,VCAN,NCAN,SPOCK2,SPOCK3,CDON,ELAVL3,ERBB2,EFS,CAMSAP1,NSG1,ZNF44,GFER,CSDC2,KCNN1,MGAT3,AFF1,MN1,ADAM22,MYH7,MYT1,NCAM1,NEFM,PCBP3,KCNK10,PFKFB2,DUSP26,SERPINI1,PLCD1,RGS12,TTLL7,SYNDIG1,SLC11A1,SNAP25,SOX2,ZCCHC24,KIF21B,ZC3H13,RGL1,WSCD1,RPGRIP1L,SLC19A3,DNAH7,R3HDM1,LAT2,SCG2,SLC17A7" Drug 2107_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "AMH,BAIAP3,CD86,DNAJB5,CPS1,CSF1R,SDC3,SNPH,KIAA0513,RIMS3,ARMCX2,AK5,DSCAM,DTNA,TOM1,ABCC9,EIF4G2,STX2,SEMA4D,DLL3,GAB1,SIGLEC8,STON1,GPR37,GRIK5,CACFD1,GRM1,ADAMTS6,ELOVL5,IL11RA,MARK1,GIT1,NOS1,CNOT4,SNTG1,PIK3R1,PPP5C,PRKAR1B,PTPRN2,GAL3ST4,RGS10,SEC61A2,ZFP30,ANKRD6,LIMS2,SLC15A2,TNIK,UNC5B,ZBTB43,MAPK8IP3,ELOVL4,VAMP1,SYN2,TMEM121,CHST8,TLR4,CABIN1,TRIM9,STMN4,NUP214" Drug 6648_UP "Clomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADORA1,SPARCL1,PPFIA4,ARHGDIG,ZSCAN18,BAIAP3,CACNG1,HAP1,CAPN3,CBS,EPS15L1,TPP1,TCEAL2,MYRIP,NCOR2,CSF1,RIMS2,DBT,C2CD2L,ELAVL3,EIF1,ZMYND10,GAD2,ADAM28,RUNDC3A,RND1,GPM6A,LILRA2,CACFD1,ICA1,MAG,AFDN,ADAM22,MT1M,NRCAM,PAK3,PALM,PDE4B,CAMKV,PMP2,LRRN3,PRPH,DCHS2,KHDRBS2,CARF,SCN2B,SLC6A9,ZNF334,ZSWIM8,UNC5B,DDN,PHF24,DAAM2,R3HDM1,TMPRSS5,CADM1,AMOT,VIPR2,LAMP5,STMN4" Drug 2276_UP Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ACTN2,CDK13,CCDC181,SYNJ2,DLGAP1,NCOR2,OSBPL3,CNTNAP2,SDC3,CTIF,BRINP1,EDNRA,PLXNC1,PIPOX,NRN1,REEP2,CORO2B,FGFR3,SCARA3,DCTN2,FYN,GPR75,LPAR4,GRIN2C,GRM8,PTGDR2,KLF12,IFI16,KCND3,MEF2C,AFDN,NDUFA5,NF1,OPCML,PFKFB2,CDK14,PLCB2,PLP1,CDIP1,LRRN3,PTHLH,PTPRB,KHDRBS2,ZNF821,MRAS,FRMPD1,ASAP3,NLGN1,SLA,SLC9A5,SOX2,HECW1,ARHGAP26,EXOC7,TBCEL,HEY2,TRPM2,FAM155A,VAV2,NT5M" Drug 5627_DN Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.77E-07 8.69E-03 6.40E-06 7.29E-05 60 198 "ADRA1D,CDC42BPA,FAM131A,PDE8B,MTMR3,GYG2,BTRC,ARHGAP33,FOXN3,TPP1,STOML1,SULT4A1,DZIP3,GIT2,ARMCX2,JAKMIP2,LYPD1,KBTBD11,EFNA3,EFNB3,RRAGB,ZNF589,FER,BAIAP2,TRAF3IP2,HBS1L,DISC1,ALDH1L1,RAB30,GLS,ELOVL5,INPP1,KHK,IPO5,LMO2,TM6SF1,CNOT4,NPTX1,LRP12,PRKAR1B,TMEM104,ELOVL2,WDTC1,PLCB1,DMXL2,TMEM121,TGFBR3,TK2,PARD3,CABIN1,TPD52,TPM1,TRIO,RUNDC3B,TRPC1,FAM155A,REEP1,SYNC,WNK1,GDPD5" Drug CID000000469 alpha-aminoadipate Stitch 1.78E-07 8.71E-03 6.41E-06 7.30E-05 30 73 "ALDH7A1,KYAT1,SLC22A6,AASDH,AASS,PIPOX,GART,GFAP,GLUL,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,IDH3A,KCNK3,NPTX1,OGDH,RLBP1,SLC1A2,SLC1A3" Drug CID000005092 rolipram Stitch 1.81E-07 8.86E-03 6.52E-06 7.42E-05 72 253 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRB2,PDE8B,ALDH7A1,CALM1,KRIT1,LRBA,CHRM1,SLIT2,AKAP6,CREM,CRYBB1,CRYM,CSNK1E,CALCRL,FABP7,DCTN2,AKAP3,DISC1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GUCY1A2,GUCY1B1,TNFAIP8L3,SYNPO,IL12A,ITGAM,KCNH2,MAP4,MBP,MYH6,NPPA,NPR2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PMP2,PTPA,PRKACB,PKIA,RAB3A,FNDC3A,SSTR1,SSTR2,KAT6B,KAT6A" Drug ctd:C016599 mono-(2-ethylhexyl)phthalate CTD 1.84E-07 9.02E-03 6.63E-06 7.54E-05 153 657 "KDM5D,ADARB2,GALNT13,ADORA1,ADRA1D,MTUS1,HECW2,HACE1,NME5,NR0B1,DISP3,AMH,KIF6,ZFAT,ANK1,LGR5,SEMA4G,SPTBN4,ARRB2,CHRD,NCOA1,ATP1A3,B3GALT2,ADAM23,CFLAR,DST,KALRN,CBS,SLC5A11,FMNL3,MTMR7,AIFM1,SCARB1,KCNAB3,LRRFIP1,LGI1,CDO1,HOMER3,CABP1,CRHBP,NCOR1,RGS6,LRIG1,ATRNL1,CHD5,NCAN,RASGEF1C,CTH,DGKB,DMD,DPP6,USH1C,EDN1,SEMA3D,EGR3,EPB41L1,ERBB4,NRN1,F3,FAM198B,ZNF461,ACSL4,PTK2B,SCARA3,ATP13A4,DPYSL4,SPECC1,ATP6V1H,BRSK1,IQGAP2,PPARGC1A,DHRS4,RND1,TOX3,AIFM3,CNTRL,BVES,HAS2,FRMD5,HMGCR,HSP90AA1,KNDC1,KCNJ16,KIF5C,TTYH2,NCOA7,MAPT,MBP,JAKMIP3,ADAM22,SCG3,MDGA1,MYCN,MYO7A,NEK1,NRCAM,OXTR,PAH,CNTN3,PDE4D,NALCN,PLCB2,ST8SIA5,PLIN1,PDZRN4,PPARA,MED1,PPP1R1A,MAPK3,EPDR1,PRPH,PTCH1,PTPRD,PTPRH,TMEM145,SLC25A48,ENOX1,RASGRF2,RGS7,ATP8B4,LGR4,RXRA,RXRG,RYR1,KIF27,SGK1,SH3BGR,DOCK10,RPH3A,EFHD1,SLIT1,RIMS1,FAIM2,SOX2,KIF21B,LHPP,CLASP2,SSTR1,EPB41L3,LRRC4,POPDC3,PDLIM2,TJP1,TLL2,RIMBP2,TPM1,STXBP4,TTPA,CADM1,VLDLR,ZBTB16,WNK2,SLC4A10" Drug ctd:C540355 1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one CTD 1.90E-07 9.32E-03 6.85E-06 7.79E-05 97 373 "ACTN1,XKR4,ADARB2,SLC12A5,ADRB2,PCDH19,DPP10,IGDCC4,CADPS,ALDH4A1,CCK,LGI1,NRXN3,TPP1,PCYT1B,COL4A5,HAPLN1,SLC32A1,CSF1,IPCEF1,GALNT9,SV2B,SPOCK3,HS3ST2,SHANK1,ST8SIA3,ATL1,EEF1A2,EGFR,SORBS3,ELAVL2,CERCAM,ELN,F3,EFEMP1,FGFR1,FGFR3,AMOTL2,FLNC,PDLIM5,GAD1,GAD2,NEK6,CPLX1,GLS,STON1,GPR22,GRIK3,NXPH2,IGFBPL1,TJAP1,ITGA7,ITGAV,KCNA1,KCNC2,KIF5A,TTYH2,NAP1L2,NPR2,DDR2,GPR88,SERPINI1,NXPH1,PRKCG,PTPN13,PTX3,ENOX1,KIRREL1,RIMKLA,LRRK2,SMPD3,PPM1E,RPH3A,SLC8A3,SLC12A4,NAPB,FAIM2,PALLD,ITPRID2,ST5,ACSBG1,SYN1,SYT1,CAMTA1,PDLIM2,PCDHB9,NACC2,DAAM2,TNS1,TPM4,VSNL1,ANKS1B,SYNC,TMEM178A,RGS7BP,MSRB3,NETO1" Drug 5906_UP valinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.92E-07 9.40E-03 6.90E-06 7.85E-05 57 185 "ARID1A,ADORA2A,SEMA6A,BEGAIN,ANK2,BTRC,CAMK2B,ARHGEF2,CDH2,CLGN,QKI,NRG2,FEZ1,FAM169A,RUSC2,DRD1,DTNA,MBNL2,DLC1,AMOTL2,FHL1,TPK1,GAB1,GAD1,RUNDC3A,GRB10,ADAMTS13,PTGDR2,HLF,JAK2,AFDN,NF1,NOVA2,RETREG1,MINDY2,PPP5C,RAD52,RPS6KA2,RYR1,SH3BP2,PPM1E,CPEB3,RPH3A,SLC6A9,SNCA,KIF21B,UNC5B,CDK19,WSCD1,PSD3,HEY1,RUNDC3B,TRPM2,VLDLR,LAT2,SLC30A3,NAV2" Drug 6173_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "ASIC1,APBB2,PLA2G4C,PDE8B,ATP1A3,SLC4A4,BTRC,NEURL1,SULT4A1,FAM149A,SLITRK5,RIPOR2,DNM1,ATN1,ABCC9,EFNA3,TNK2,C3orf18,MTSS1L,ERBB2,FGFR1,BAIAP2,FOXG1,SEPT9,GLRB,GNAO1,GRK4,GRM8,GUCY1A1,PADI2,PTGDR2,KCNC1,KCNF1,CD200,MYO7A,NCAM1,NEFM,NRGN,NTRK2,NUCB1,OPRL1,EMID1,SATB1,GALNT10,PPP1R9A,KDM4B,ZNF423,NFASC,SYT1,TRIM2,HIF3A,SLC44A1,TK2,RBFOX2,LILRA4,OSBP2,CLIP2,TRIM9,ADAMTSL3" Drug 6090_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "C1QTNF3,ALCAM,APOC1,ARHGDIG,ARRB1,MARK4,ALDH4A1,GYG2,ARHGEF2,ADGRG1,HOMER3,PDE4DIP,RUSC2,DUSP9,HIPK3,ING4,STX2,NCALD,RRAGB,ZNF589,KIAA1109,CGREF1,SRCAP,ZNF276,GLS,GPER1,GRB10,GRM1,MBD1,MID1,NEK1,NF1,PCDH9,PRKAR1B,ZSCAN2,RGS10,WLS,PEX26,EPN2,SMTN,LIMS2,FAM214B,SLC6A8,WDTC1,ZCCHC24,EMC1,CDK19,TSPYL2,MAPK8IP3,VPS13A,SYN2,EXOC7,ARHGEF12,TGFBR3,ZNF34,CABIN1,ZFP37,PRDM2,SENP7" Drug 6757_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "KIDINS220,SEMA6A,AQP6,ASCL1,MYOM1,BMP7,MYRF,BAIAP3,SLC16A4,DLGAP1,CHRNA4,NRXN3,GAL3ST1,IFFO1,CSF1,LRIG1,PPP1R16B,DMPK,DRD1,DRP2,ST8SIA3,ING4,SRPK3,EFS,EFCAB2,B3GAT1,ERAP1,RUNDC3A,GRIK3,GRIK5,GRM7,KCNJ5,PACRG,MDFI,MT1M,MYBPC1,MYH3,NPY,PDE3B,PPP1R1A,PTPRH,MARCH1,C1orf54,PNMA8A,SCN2B,PPM1E,CNKSR2,RIMS1,SNCA,CDK19,VAMP1,SYP,SYT5,THRA,TK2,BHLHB9,CADM1,VAV2,NT5M" Drug 6308_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "ASPHD1,ALAD,SHROOM2,PDE8B,SLC4A4,CADM3,BACH1,NRP2,CFLAR,SYNJ2,CACNA1G,MAP7,LHX2,HOMER3,HAPLN1,VCAN,USP6NL,CELSR3,PLXNC1,DMTN,IGSF6,F5,ST3GAL6,TESK2,C1orf61,PRELID3A,ZNF44,DENND2A,GAP43,USP19,ZNF276,GPR22,RAPGEF4,GRM8,IL12A,KPNA5,VWA5A,NOVA2,NPTX1,PCDH9,PFKFB2,MAPK8,SAMD9,SNRK,PTHLH,PEX5,RAB3A,RAB3IL1,RNASEL,MYH14,FRMPD1,ST6GAL1,DZIP1,SNCA,TK2,REEP1,SEMA3B,SMIM8,DPF3" Drug 4455_DN 15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "PLA2G6,C1QTNF3,LTBP4,CDC42BPA,PPP4R4,MARK4,ADGRB2,IL33,ARHGAP33,CHN2,NRXN3,DNAJB5,WHRN,TCEAL2,PPP6R2,FAM131B,TBC1D5,ARMCX2,EGFR,PLXNC1,ETV1,FGF1,SEMA4D,PNMA2,GAD1,ERAP1,INPP5K,GPM6B,GPR37,CNTRL,KLF12,JAK2,MDFI,MEF2C,GIT1,TAGLN3,NF1,ODF2,CLDN11,PBX1,PDE4D,PFKFB4,PLCB2,POU3F2,MINDY2,ARHGEF10L,CSRNP3,WDTC1,DDN,LHPP,ST5,MAPK8IP3,SEMA4A,WSCD1,SYNE1,TNS2,DNAH7,DNAJC12,SPHK2" Drug 6424_UP F0447-0125; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "ARID1A,BIN1,GAS7,ARNTL,RASL11B,ALDH4A1,CFLAR,CA4,SCARB1,FOXN3,PLAA,QKI,AKAP7,WHRN,CREM,RIMS2,CYBB,DAPK3,JAKMIP2,DTNA,EIF4G2,ING4,ETV1,FGF1,AGAP2,GAB1,GAD1,DISC1,RUNDC3A,STMN2,RASSF8,SCRG1,ICA1,IL6R,ITPKB,MEF2C,ZNF862,NCF2,NFYA,PLPPR1,C1orf54,SATB1,DOCK10,SLC1A6,SLC6A8,BTBD7,SLN,WDTC1,ZCCHC24,KIF21B,SS18,WSCD1,TRIM2,AP4E1,ZNF34,HEY1,LMF1,SLC13A3,ZFP37" Drug 4269_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.95E-07 9.55E-03 6.98E-06 7.94E-05 59 194 "NR0B1,APC,CACNA1I,CD38,CHRNA4,EPS15L1,RGS6,VCAN,DGKB,ATN1,EDNRA,EFNB3,MRNIP,RASGRP2,EPHB1,F5,REEP2,CORO2B,KIAA1109,FYB1,ADAM28,GNG4,GPD1,GRM8,PTGDR2,ICA1,LMO2,MSI1,TAGLN3,MYT1,FXYD7,NOVA2,OMG,PDE4B,CAMKV,EPN1,LRRN3,PRPH,PTPRB,RGS4,SELL,DZIP1,SLC8A1,CXXC4,WDTC1,KIF21B,ARHGAP26,NPAS3,SSTR2,MAPK8IP3,PLCB1,TACR1,MCF2L,KLHL4,TEX15,TK2,LILRA4,TRPC3,DPF3" Drug CID000005304 strychnine HCl Stitch 2.10E-07 1.03E-02 7.48E-06 8.51E-05 56 181 "ABAT,ASIC1,SLC12A5,AMT,APOC2,CBS,ASIC3,CHRM1,CHRNA4,CHRNB2,SLC32A1,CST3,DMPK,GPHN,ADGRV1,SDCBP2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,AHDC1,GFAP,GLRB,POLL,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,GSTM5,GSTT2,HMGCR,MEST,NOVA1,PTCH1,GSTCD,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC1A7,SCN3B,SULF2,JMJD6" Drug 5579_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.14E-07 1.05E-02 7.48E-06 8.51E-05 58 190 "DPF1,OSBPL1A,BIN1,ARHGAP5,DNAH17,MPDZ,CFLAR,GYG2,DNAJB5,QKI,NECTIN3,AATK,MICAL2,SPOCK2,MFAP3L,DRD1,DTNA,EDN1,EDNRA,EFNB3,C3orf18,AMOTL2,CAP2,AFF2,FYN,DISC1,SRCAP,GNAS,NR3C1,HLF,IL6R,AFDN,MN1,NAP1L2,NINJ2,P2RY1,CDK18,KLK6,ENOX1,SYNDIG1,HSPA4L,SH3BGR,DOCK10,KANSL3,CCDC88A,ZNF334,SLN,TNIK,ZNF423,ROBO3,WSCD1,ZEB1,TRIM2,PCDHGA10,DICER1,UCHL1,SLC30A3,FXR1" Drug 6602_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "SEMA6A,AMH,GAS7,APOC1,ATP6V0A1,GYG2,CACNA1D,CACNB4,CAST,NEURL1,CRMP1,ATRNL1,MFAP3L,DRD1,EDN1,PLXNC1,CALCRL,F5,DCTN2,NSG1,GAD2,GATM,GRM1,GUCY1A2,PADI2,HLF,KCNJ3,PACRG,MGAT3,MYH7,NEFM,NF1,NOVA1,NPPA,DDR2,PDE4B,MTRF1L,SPATA6,POLG,PROX1,PTPRB,RGS12,FBXW7,EMID1,MRAS,FRMPD1,PPP4R3A,LHPP,PLCB1,SYT5,MCF2L,PCDHA5,TEX15,THRA,TIMP4,TLR4,FLRT1,KCNK12,KCNAB1,MVB12B" Drug 6749_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "AGT,NME5,LTBP4,PTCH2,SLC4A4,ADGRB2,SYNJ2,IL33,CFAP410,CACNA2D1,SOCS6,ASIC3,CHRNB2,ARHGAP22,CNTFR,CNTN1,CRY2,DAPK3,C2CD2L,DRP2,ECM2,SCML2,CORO2B,BAIAP2,FOXG1,DCTN2,EFCAB2,PRELID3A,B3GAT1,KCNMB4,GNG3,CACFD1,GRM8,HNMT,MDFI,MX1,NF1,NOVA2,PAH,PDE4A,RETREG1,RAB3IL1,CCDC40,ENOX1,MYH14,IL17RB,ZNF821,CPEB3,SLC4A3,SLC8A1,ZHX3,SP4,KDM4C,ATP10B,ST5,NCDN,TEX15,TPM2,HIRA,TFIP11" Drug 3485_DN Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "NDRG2,AP1B1,APC,FAM131A,APOC1,PPFIA3,ASPH,ALDH4A1,BMP7,CFAP410,CRLF1,TAOK2,ZFYVE9,VAX2,SULT4A1,ABI3BP,BAG4,PDE4DIP,MFAP3L,RABGAP1L,DSCAM,DTNA,EML1,LRRC23,EZH1,FAM198B,MALT1,GNG4,LPAR4,KCNH2,KITLG,GIT1,NUMA1,PBX1,SLC25A23,MAPK8,MAPK10,CCDC25,NEK11,SAFB,ZKSCAN3,LIMCH1,WDTC1,EMC1,CDK19,ZBTB43,LHPP,CAMTA2,SEMA4A,MGRN1,TNS2,ZNF34,TMOD1,TRPC1,PLPPR2,MICAL1,KLC2,KCNK12,ZNF45,MPPE1" Drug 4140_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "KIDINS220,AMPD3,CNTNAP1,APBA2,MARK4,ASPH,BRINP2,ATM,CADM3,CA4,CACNA1D,STOML1,FADS2,ABI3BP,ARHGEF10,PDE4DIP,CNTNAP2,GREB1,HS3ST2,DUSP9,MBNL2,FHL1,AFF2,FAM49B,GPR153,ARFIP1,ADAM28,GPD2,PRUNE2,ADAMTS13,GRM8,IL6ST,JAK2,KCND3,KCNH2,KCNMA1,MAP4,KITLG,ADAM22,TAGLN3,NDUFA5,NEK1,NELL2,NNAT,CNNM2,ZMAT4,SEMA6D,SLA,CCDC88A,COA1,SNCA,ZC3H13,AJAP1,TBCEL,SMG6,PCDHGB6,PSD3,HEY2,XRCC4,SLC17A7" Drug 4704_UP Evoxine [522-11-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "DPF1,ASIC1,PLA2G6,LGR5,PLA2G4C,CACNB2,ARHGEF1,CACNA2D2,ASIC3,QKI,SULT4A1,CRMP1,CSF1,ST18,GIT2,ZNF804A,EDNRB,VPS13B,EFS,SPEG,RRAGB,KHDRBS3,GAD2,GLYR1,RAB30,GPM6B,TDRKH,CACFD1,NR3C1,GRM1,GSN,GUCY1A2,KLF12,INPP1,INPP5B,JAK2,KCNJ3,KCNMA1,MMP16,BCO1,CNOT4,P2RY1,PLCB2,ATG16L1,C1orf54,CCDC25,SELL,MRAS,SORCS3,PHLDB1,STX1A,SYP,KIAA1107,DOCK9,PCDHA6,TNS1,CDK20,ZKSCAN5,NT5M,SSPN" Drug 6394_UP C75; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADD2,NR0B1,LTBP4,ANK1,PPFIA2,APOC1,ASCL1,ATP2B2,BACH1,CACNA1I,ARHGAP33,CACNA2D2,SOCS6,EPS15L1,TPP1,STOML1,AKAP5,CPS1,MICAL2,PLCH2,SPOCK2,DNAJC6,ELMO1,SPOCK3,ATN1,EGFR,AASS,TENM1,FOXG1,AFF2,FOLR2,SORBS1,GFAP,ADAMTS13,HLF,ITIH2,KCNJ5,KCNMA1,ADAM22,MSR1,MYO7A,NNAT,PDGFRA,PENK,GDAP1L1,CDIP1,LRRN3,RGS4,DOCK10,SLCO1A2,KIF21B,UNC5B,COLGALT2,SYN2,WSCD1,TRPM2,UCHL1,PRDM2,ITM2C,CAMK1G" Drug 2655_UP Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASPHD1,ASIC2,TRMT9B,KCNAB2,APLP1,CDK10,MARK4,CACNB2,USP2,ARHGEF1,ARHGAP33,CBARP,CSF1,ARHGEF10,RASSF2,C2CD2L,SPOCK3,HS3ST2,USH1C,EFNB3,EN2,SEMA4D,GPR153,AHDC1,MUM1,ATXN2L,LAMA2,MMP17,NPTX1,OPRL1,KCNK10,PDE3B,PLTP,LRP12,PPP1R1A,PRODH,PTPRO,KHDRBS2,RGS10,RGS12,RPS6KA2,SCN8A,TRIM46,SH3BP2,SLC1A7,SHANK2,BTBD7,SPTAN1,IQSEC2,SYN1,ARC,TACR1,TIAM1,PARD3,TSN,VSNL1,WIPF1,KLC2,GDPD5,SEMA3B" Drug 4641_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASIC1,CDC42BPA,PDE8B,ASTN1,ATP2B2,BAIAP3,CDC42,CDH10,BAG4,CPS1,CSF1R,SDC3,ARHGEF4,CTNND2,FAM131B,MFAP3L,SMG7,SPOCK3,AASS,MRNIP,NRN1,KIAA1109,SCARA3,FOXG1,ANKFY1,ZNF44,GFER,LIG4,NDUFA5,OPCML,PPARA,FAM120C,PEX5,RGR,KLHDC8A,TRAPPC13,FOXRED2,CSRNP3,ATXN7,SUPT20H,FRMPD1,SLA,SLC1A7,SLN,MYH15,TNIK,CAND2,DDN,TCF4,ARHGEF12,TGFBR3,TIMP4,BHLHB9,RIMBP2,RUNDC3B,AMACR,SF1,NT5M,KCNAB1,KAT6A" Drug 4378_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ALK,TRMT9B,GAS7,APOC1,CDK13,CCDC181,ATP1A2,AZGP1,CFLAR,MTMR3,HIP1R,KCNAB3,SULT4A1,ENTPD4,NOS1AP,CTIF,EXOG,DTNA,TENM1,ELAVL2,F5,FGF1,FLNC,SORBS1,GAD2,ATP8A2,NEU3,GPM6B,GRM7,NXPH3,PTGDR2,HTR2A,KCNN1,KPNA5,MEIS1,ADAM22,NPTX2,OGG1,PDE1C,PFKFB2,TNPO2,GDPD2,PTPRO,RAD52,PNMA8A,TMEM206,EMID1,STUM,RPH3A,SLC2A5,BTBD7,SORCS3,SNAP25,SYT11,VAMP1,TBCEL,LAT2,PRDM10,KCNAB1,MVB12B" Drug 2803_DN Yohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "SRPX,AMPD3,CDC42BPA,GAS7,APOC1,SEMA4G,PPP4R4,ARHGDIG,CADM3,ATP6V0A1,CFLAR,MTMR3,GYG2,CACNA1D,CRLF1,ADGRG1,FOXN3,SULT4A1,AKAP5,CSF1,RIMS3,SPOCK2,JAKMIP2,MFAP3L,LYPD1,RABGAP1L,SIDT2,KIAA1109,FGFR1,FHL1,B4GALNT1,SRCAP,MSL3,INPP1,KHK,LMO2,SMAD1,MAP4,MOBP,MX1,NPTX1,PC,NLE1,PRPH,GTDC1,TCP11L1,SLN,SMARCA4,LIMCH1,WDTC1,ZCCHC24,ZHX3,EMC1,TGFBR3,HEY2,PARD3,MICAL1,ZFP37,KCNAB1,EPM2A" Drug 4166_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "APBA2,KCNAB2,APOC1,MARK4,AZGP1,GYG2,CACNG1,RUNX1T1,CDH2,TAOK2,STOML1,WHRN,CREB5,MICAL2,PLCH2,DAPK1,KLHL3,DMPK,EDN1,EFNB3,EGR3,EIF4G2,KCNMB2,SCARA3,FOXG1,SORBS1,FYB1,ZNF44,GABRA5,ALDH1L1,GDF9,GPER1,NR3C1,GRM1,GUCY1A2,IL6R,KCNC1,NOVA1,NTRK2,GPR85,ELOVL2,RGS12,PKNOX2,FAIM2,KDM4B,WDTC1,ZCCHC24,SPART,POPDC3,DMXL2,PCDHGB6,DOCK9,TMEM151B,ARHGEF12,SLC35G2,DNAH7,TNS1,SLC30A3,STMN4,SLC17A7" Drug 6403_DN valdecoxib; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASIC1,C1QTNF3,TRMT9B,APBB2,GAS7,ATP1A3,ADAM23,ADGRB2,BTK,BAIAP3,CA4,CACNA1A,CAMK2B,CBFA2T2,CDC42,CDH8,CREM,CSF1R,VCAN,RIMS2,USH1C,EDNRA,EN2,ERCC2,CACNG3,SCML2,CAMSAP1,PDLIM5,ATP8A2,SRCAP,CSDC2,PRUNE2,GRM2,GUCY1B1,HNMT,ICA1,IFI16,IL11RA,INPP5B,KCNK2,KCNN1,ADAM22,NPPA,PURG,SPATA6,PPARA,PRKAR1B,MAPK8,RELN,ZDHHC14,RPS6KA2,CCDC88A,TAC3,ROBO3,DMXL2,ZEB1,PCDHA5,SLC35G2,TRO,MVB12B" Drug 3306_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADCY2,ADRA1D,C1QTNF1,SPARCL1,CDC42BPA,APBA2,APC,ST3GAL5,CACNA1I,BAIAP3,CFAP410,CAMK2G,CBFA2T2,NEURL1,SEPT7,FOXN3,ASIC3,TAOK2,TPP1,WHRN,NOS1AP,MAMLD1,EGR3,EIF4G2,ELAVL2,PTK2B,OLFM1,GAD1,GLYR1,GPM6A,NR3C1,KCNB1,KIT,MOBP,TAGLN3,MX1,ZNF862,CEP41,MAPK10,PLPPR1,PTHLH,PTN,KCTD17,SLC6A8,SLC11A1,SHANK2,MYH15,DOK5,ARC,SYT5,WSCD1,TCF4,ZEB1,PCDHGA10,TIAM1,TRIO,WIPF1,KCNK12,NAV2,KAT6A" Drug 6660_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASPHD1,LGR5,CDK10,ATP1A2,ATP6V0A1,ADGRB2,CFLAR,BMP7,MTMR3,CACNA2D2,JAM2,STOML1,SULT4A1,PDE4DIP,C2CD2L,DTNB,EPHB1,ZNF549,ETV1,REEP2,OLFM1,FGFR1,PRELID3A,NSG1,TBR1,OGA,GAB1,GAD2,CSDC2,GRIK5,GRM3,GSN,SHISAL1,ITGA7,KCNMA1,KIT,BCO1,NCAM1,CLDN11,PDE4B,EPN1,POU6F1,MAPK8,MAPK10,ZSCAN32,PTPRO,TCP11L1,DZIP1,SLA,SLC12A4,TNIK,PCDHGB6,TPM2,UGT8,LAT2,KCNK12,ZNF225,WNK1,PRDM10,NUP214" Drug 5499_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "SEMA6A,SEMA7A,APLP1,MARK4,SLC4A4,ALDH7A1,N4BP2L1,CCNT1,CACNA2D2,PLEKHB1,KIAA1549L,NRG2,FEZ1,DTNA,FAM13A,DMTN,RASGRP2,SPEG,BAIAP2,IQCG,PDLIM5,GAB1,GABRA2,GAP43,GATM,SRCAP,RUNDC3A,GPM6B,GRIN1,IPO5,MSR1,OPCML,EPN1,LRP12,PACSIN1,PPP2R2B,MAPK7,MRAS,BCAN,ABLIM3,SLC1A7,ELMO2,SLN,SNCA,SOX2,ZHX3,DDN,CLSTN2,ZFR2,SYN2,SEMA4A,PCDHGA10,PSD3,WBP2,TRIO,AMACR,ZMYND8,MICAL1,ADAMTS9,PAK5" Drug 4381_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ALCAM,ANK1,APLP1,APOC1,ALDH7A1,CADM3,CDK5R2,CAMK2B,ARHGEF2,DNAJB5,SULT4A1,CNR1,ENTPD4,ARHGAP24,INTS1,EXOG,CDON,ELN,EN2,KCNMB2,ERBB2,AFF2,CAMKK2,SIGLEC8,GPER1,RAPGEF1,KCNJ4,KCNJ5,KCNN1,NTRK3,PCDH8,PLCD1,PLCL1,PPARA,MINDY2,PTPRN2,RGR,RNASEL,RPS6KA2,EMID1,KCNIP1,ZNF821,ASAP3,CPEB3,FNDC3A,PREX2,PKNOX2,BTBD7,LIMCH1,UNC5B,VAMP1,POPDC3,WSCD1,SLC35G2,R3HDM1,TNS1,UCHL1,VIPR2,SLC17A7,AP3B2" Drug 5538_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "RALGAPA1,ASPHD1,ACTN2,SYT13,APC,CHRD,ASTN1,LDLRAD4,TAOK2,STOML1,QKI,CPS1,CSF1,CSF1R,ATRNL1,RIMS2,RASSF2,DYRK1A,RASGRP2,CORO2B,CAMSAP1,FHL1,FOXG1,TPK1,SIGLEC8,GNAO1,GPM6B,GRB10,GRM8,KCNN1,LIFR,ADAM22,MX1,NOS1,PDE4B,ENPP2,CAMKV,SLC25A23,STRN3,NECAB2,FSD1,PPARA,TCP11L1,RPS6KA2,EMID1,SH3BP2,FRMPD1,SLC2A5,SMTN,SLC11A1,SLN,ERC1,AJAP1,TACR1,MCF2L,SEZ6L,TRO,SPHK2,DNALI1,HPS4" Drug 5856_UP Milrinone [78415-72-2]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "RALGAPA1,PLA2G6,ARRB2,CHRNB2,NRXN3,CLTB,QKI,CNTFR,CNTN1,DZIP3,TOX,TBC1D5,LYPD1,PARD6A,ECM2,EDIL3,EFNB3,FAM13A,EGFR,RASGRP2,ETV1,OGA,FYB1,ERAP1,GCNT2,SRCAP,GPM6B,LILRA2,PADI2,INPP5B,KCNA2,MAPT,CD200,CNOT4,PCSK2,CAMKV,POU3F2,PRODH,BCAS3,MARCH1,UEVLD,SCN8A,SLA,SLC1A7,KDM4D,FAIM2,ATP10B,ACSBG1,COBL,KAZN,TAL1,PCDHGB6,PSD3,OBSL1,R3HDM1,CHST5,NT5M,STMN4,UBE3B,DPF3" Drug 6324_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ARID1A,ADCY6,APAF1,EPB41L5,PPP4R4,PDE8B,DNAH17,MARK4,BMP7,BAIAP3,USP2,ABCG2,CREM,NCOR2,AATK,CTNND2,ARHGAP24,DAPK3,MFAP3L,EXOG,CDON,ATN1,SIDT2,IRAK4,FAM198B,KIAA1109,FGF1,CAMSAP1,SCARA3,ERAP1,ZNF276,GLYR1,LPAR4,RAPGEF4,IRAK3,KCNJ5,KHK,LIG4,SMAD1,NECAB2,POLG,MAPK7,MAPK8,PROX1,MASP1,WDR25,ZSCAN32,GAL3ST4,ROM1,ITSN1,NLGN1,SLA,ELMO2,PHLDB1,ASTN2,ADGRL3,ARHGEF12,TEX15,LMF1,NUP214" Drug 2266_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ACHE,NDRG2,ADCY6,AK2,ALK,SEMA7A,GAS7,ARHGDIG,ADAM23,FGF17,KSR1,CACNA1D,TPP1,MYRIP,CRMP1,NCOR2,CSF1,RUSC2,ATN1,EIF4G2,MTSS1L,EPHB1,ERCC2,FABP7,DLC1,OLFM1,FGFR1,B3GAT1,GABRA2,SEPT9,ATF7,GPER1,GRIN2C,GRM8,IRAK3,HLF,KIF5A,MEF2C,MYH7,NPPA,PCBP3,GPR85,PFKFB2,PRKCB,CNTLN,C1orf54,KLHL11,FRMPD1,ASAP3,SLA,KANSL3,SLC11A1,SOX2,ARHGAP26,MAPK8IP3,SYT5,CRTC1,TEX15,VIPR2,KCNK12" Drug 4261_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADCY6,MTUS1,APC,SHROOM2,CDK10,SEMA4G,ST3GAL5,SCARB1,CLCN4,RAB26,CREM,SLITRK5,DBT,CNIH3,KIAA0753,PLPPR4,SGSM2,FCF1,EFNA3,FAM13A,ETV1,FGFR1,ANKFY1,TRMO,SORBS1,DENND2A,GLI2,GLYR1,EML4,CNTRL,KIF3A,DIPK1A,JAK2,TAGLN3,MTR,NDP,CLDN11,PAK3,PIK3R1,CCSER2,RETREG1,RC3H2,MAPK9,GRAMD1C,ZSCAN32,TMEM231,FBXW7,SUPT20H,FNDC3A,SMARCD3,CAND2,SPTAN1,ARHGEF9,WWC1,IQCE,ARHGEF12,SSBP2,WIPF1,NSD2,EMSY" Drug 6168_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "NR0B1,PLA2G6,ANK3,APBB2,LGR5,PDE8B,ATP2B2,NRP2,SCAPER,THSD7A,CRLF1,CHRM4,CLCN4,SULT4A1,CRY2,DAPK3,SPOCK2,DLG3,HS3ST2,TRAPPC9,EFNB3,TNK2,MRNIP,VPS13B,KCNMB2,STX2,EYA1,FHL1,HPCAL4,FERMT2,GPD1,CACFD1,GUCY1A2,SCRG1,SYNPO,KCNN1,MOBP,NRCAM,PFKFB2,RETREG1,ACSS3,SCG5,SH3BGR,SH3BP2,CNKSR2,SHANK2,SLCO1A2,SP4,LHPP,RPGRIP1L,ICAM5,RUNDC3B,ZMYND8,TUBB1,UBE3A,OSBP2,VGF,SLC17A7,KCNAB1,HRASLS" Drug 6098_UP Streptozotocin [18883-66-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADD2,ADRA1B,BIN1,CNTNAP1,SEMA4G,RGS20,BACH1,CFLAR,USP2,ARHGAP33,AKAP7,WHRN,SH2B1,IPCEF1,SLITRK5,BRINP1,KLHL3,DMD,ST8SIA3,HEYL,EFCAB2,PDLIM5,GCNT2,SRCAP,GRK4,GRB10,GRM7,SOX21,GUCY1A2,HPSE2,C2orf72,TJAP1,KCNN1,KIT,AFDN,CD200,MSR1,NPPA,P2RY1,SNTG1,CDK18,LRP12,POU3F4,MAPK8,PTHLH,CCDC40,SUGCT,TCP11L1,SHANK2,HECW1,SPTAN1,INKA2,POPDC3,SZT2,PCDHGA1,DAAM2,R3HDM1,UBE3A,SPHK2,GJC2" Drug 5688_UP Altretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADGRF5,SPARCL1,SYT13,CDC42BPA,ANK1,APAF1,PRX,ASTN1,CADM3,LDLRAD4,CACNG1,SEPT7,CHRNA4,SLIT2,FADS2,WHRN,CHD5,VCAN,ARHGAP24,CDON,SLC12A6,EDN3,EGFR,MRNIP,RASGRP2,FGFR3,FOXG1,FLT1,GAD2,RAB30,GPM6B,GPR22,GRIA1,SOX21,GUCY1B1,WIF1,SYNPO,MEF2C,MGAT3,PDE4D,PFKFB2,MAGEL2,MASP1,PTH1R,RAB3A,RGS12,TCP11L1,ZNF821,SORCS3,MYH15,SAMSN1,PLCB1,POPDC3,TAC3,PCDHGB6,DOCK9,CA14,WIPF1,EPM2A,HRASLS" Drug 2625_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ADCY6,ADD2,LTBP4,MRTFA,KCNAB2,PDE8B,ALDH4A1,SLC2A11,ATP6V0A1,ADAM23,BCL2L2,CACNA1I,CACNA1G,ZFYVE9,CLU,STOML1,LY86,AKAP7,LRIG1,PDE4DIP,DCT,ELMO1,C3orf18,FCGRT,ZNF589,IQCG,GPR153,GAD2,PCDH17,GLS,ATF7,CELF3,RASSF8,PTGDR2,MAP4,MDFI,NCF2,NELL2,NF1,NTRK3,OMG,PIK3CD,SLC25A23,PTN,RAB3A,RAD52,TRIM68,PKNOX2,SLC20A2,KIF13A,ZC3H13,IQSEC2,ST5,MAPK8IP3,VAMP1,PARD3,VAV2,MVB12B,SMIM8,NUP214" Drug 5540_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ACTN2,LTBP4,BIN1,CDC42BPA,APC,GAS7,PPFIA3,CDK10,RASL11B,ALDH7A1,CADM3,MTMR3,KRIT1,SLC16A4,FOXN3,STOML1,SULT4A1,AKAP7,MYRIP,NRG2,CSF1,CSF1R,PDE4DIP,SDC3,RIMS2,DCAF8,TM9SF4,DAPK3,BRINP1,CHRDL1,SIDT2,EN2,MTSS1L,SCML2,DLC1,GABRA4,SRCAP,GNG3,GPR37,ATXN2L,HNMT,ICA1,JAK2,KCNN1,ADAM22,NDUFA5,PLCD1,LRP12,RIPOR1,RAD52,TCP11L1,MAP6D1,SYBU,WDTC1,KDM4C,WSCD1,TK2,TNS1,EVI5,PHTF2" Drug 6657_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASPHD1,ADORA2A,ADRA1D,AMPH,APBB1,LGR5,ATP2B2,ADGRB2,FGF17,BAIAP3,SLC16A4,CD86,EPS15L1,NRXN3,ARHGEF10,SUSD5,CTNND2,C2CD2L,SRGAP3,ATN1,EDN1,ING4,ETV1,OLFM1,FOXG1,OGA,GATM,POLL,GPR17,ATXN2L,MMP16,SCG3,MYL3,NPPA,PALM,PDE4B,ENPP2,POU6F1,GDPD2,PTAFR,PTN,TMEM231,FAM184A,RASGRF1,RGS12,FBXW7,SCN2A,DOCK10,SLC6A8,SLC9A5,ZNF334,ZHX3,KDM4C,SPTB,RBM26,SYN2,MCF2L,CRTC1,RIMBP2,HIRA" Drug 4645_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASPHD1,APC,ASCL1,ASTN1,CADM3,ADGRB2,RGS9,BMP7,SYNJ2,BAIAP3,BTRC,CFAP410,CACNA1D,SLC16A4,RAB26,RGS6,MYEF2,C2CD2L,ARNT2,TOM1,MTSS1L,EFS,ANKMY1,EZH1,OLFM1,FGFR3,FLT1,NEU3,GLI2,TOX3,POLL,GNAL,STON1,STMN2,GRIK2,GRIK3,ADAMTS8,GRM1,GRM8,KLF12,KCND3,KCNJ4,LAMA2,MBNL1,ADAM11,MYH6,OPRL1,PCSK5,PPP1R1A,PTPRG,SELL,SLC2A5,ZC3H13,SYT5,TACR1,SPX,LILRA4,TRO,KCNK12,MKRN3" Drug 2763_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "C1QTNF1,ANK1,DDO,SEMA4G,MARK4,N4BP2L1,KALRN,HAP1,SLC16A4,NEURL1,LHX2,CLCN4,CNTN1,RIMS3,SPOCK2,DBT,DMD,SLC12A6,DRD1,EDIL3,PLXNC1,EIF4G2,C3orf18,FGFR3,FHL1,ALDH1L1,ADAMTS13,GRIN1,GUCY1B1,ATXN2L,ELOVL5,IRF8,IGF1,IL6ST,MSR1,TAGLN3,NUMA1,OMG,PDGFRA,PLP1,ELOVL2,CCDC40,SYNDIG1,KCNIP1,RASA3,ASAP3,FAM214B,SLC9A5,LIMCH1,SYT5,WSCD1,DICER1,FLRT2,VIPR2,LAT2,XRCC4,ZNF45,NT5M,PHTF2,DPF3" Drug 7366_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "NME5,AMT,CDC42BPA,KCNAB2,EPB41L5,SHROOM2,MARK4,ASPH,CFLAR,BTRC,KALRN,CACNA2D2,FOXN3,PLEKHB1,DNAJB5,WHRN,SLC4A8,EDRF1,PARD6A,CHRDL1,DPH1,CNNM1,EFNA3,FAM13A,EGFR,MBNL2,DENND4A,ETV1,PNMA2,FYN,GLYR1,DIPK1A,ITIH2,KIF5C,NOS1,PDGFRA,PRKAR1B,TMEM104,PTCH1,PTH1R,RAD51D,RAD52,FAM184A,FBXW7,CLIP1,ATXN1,FBXO11,DZIP1,SLC20A2,SMARCC2,TSNAXIP1,ZHX3,DDN,TCF7L2,CRTC1,ZKSCAN5,KCNAB1,UBE3B,KAT6A,NUP214" Drug 4423_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASIC1,ADORA1,ADRA1B,APC,DNAH17,CFAP410,CALB2,HIP1R,LDB2,GPR37L1,TPP1,OSBPL3,CNTNAP2,PHF14,DGKG,DRD1,ELAVL3,ELN,RASGRP2,CEND1,DLC1,KIAA1109,OLFM1,ERAP1,ATP8A2,RUNDC3A,GPM6B,GPER1,GRIK5,GRIN1,SYNPO,INSM1,LAMA2,VWA5A,MAPT,MDFI,BCO1,MX1,P2RX7,PFKFB2,EPN1,TNPO2,PPARA,PTAFR,PID1,GAL3ST4,TRIM68,ASIC4,MRAS,ST6GAL1,ARHGEF40,OGDHL,PEG10,ARHGAP26,TAL1,DOCK9,WIPF1,MKRN3,SSPN,DPF3" Drug 2376_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "NDRG2,ADRA1D,SEMA6A,AMPD3,APAF1,APP,CDC14B,ARHGDIG,ARRB1,DNAH17,ALDH4A1,GYG2,C5,CHRNA4,TCEAL2,SPOCK2,DBT,DNAJC6,NTM,DLG4,DSCAM,EEF1A2,OPTN,ELN,RASGRP2,FHL1,CELF1,FYB1,GNG4,GRM7,BTN2A1,ATXN2L,JAK2,MN1,MYCN,MYO7A,NEK1,NF1,NUMA1,OPRL1,GPR173,PACSIN1,FSD1,MAPK10,CNNM2,CRTAC1,SYNDIG1,DOP1A,SOX10,PDLIM2,TBCEL,CRTC1,TEK,RBFOX2,TPM3,SSBP2,FLRT2,BEST1,EMSY,PLSCR4" Drug 7210_UP Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "NME5,AMT,APBB2,APLP1,ARRB1,MARK4,ATP2A2,ATP2B2,CADM3,KSR1,SCAPER,CA4,CALB1,CALB2,CAMK2G,SLC16A4,TMEM59L,PCYT1B,FEZ1,ARHGEF10,SDC3,DUSP9,PHF20L1,KCNMB2,ERCC2,F5,DLC1,KIAA1109,FHL1,GALC,GCNT2,GLYR1,GLS,BTN2A1,RNFT2,ELOVL5,KCND3,KCNF1,GIT1,ZNF862,NEK1,PDE1C,LRP12,PPP2R2B,ZSCAN32,ZSCAN2,RAD52,KHDRBS2,BSDC1,ZFP30,FRMPD1,SNCA,TTBK2,POPDC3,PCDHGA1,DOCK9,TMOD1,RIMBP2,WNK1,ITM2C" Drug 6379_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "DPF1,RALGAPA1,ADCY6,PKP4,BCAS1,PPP4R4,ASPH,SLC2A11,BACH1,CDK5R1,ASIC3,CHN2,PICK1,COL9A2,ENTPD4,ERC2,PYGO1,RIMS3,CNIH3,DSCAM,DTNA,USH1C,FCF1,FRY,CELSR3,EGFR,ZNF391,FGF1,FGFR1,ERAP1,CPLX2,RUNDC3A,POLL,GPM6A,GPR17,IRF8,KCNB1,KCND3,KIFC3,ODF2,SERPINI1,NECAB2,TNPO2,MINDY2,CNTLN,ZSCAN2,ZNF671,RYR1,ASAP3,SLC11A1,RIMS1,EMC1,DDN,LHPP,MAPK8IP3,SYT1,DMXL2,TRPC3,XRCC4,ZBTB14" Drug 5997_UP Imipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ASPHD1,ADGRF5,CDC42BPA,GAS7,APP,ARHGDIG,SCAPER,BRSK2,RCBTB2,TAOK2,DNAJB5,CRMP1,PDE4DIP,EFNA3,EBI3,EGFR,C3orf18,VPS13B,RASGRP2,FHL1,SCARA3,CAMKK2,GAD2,DISC1,GFAP,RUNDC3A,PCLO,NR3C1,GRM7,GSN,ATXN2L,KCNJ5,MAP4,MDM4,BCO1,DDX25,NEUROD1,CDK14,VPS13C,RGR,TTLL7,KLHL11,SYNDIG1,SELL,PKNOX2,SNAP25,SSTR2,RGL1,VAMP1,SYP,SYT5,PCDHGA10,TNS1,UGT8,MICAL1,LAT2,CLDND1,DNALI1,ITM2C,HRASLS" Drug 4765_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ARID1A,ADRA1D,LTBP4,ARHGDIG,GYG2,CFAP410,AP4M1,ARHGEF2,ARHGAP33,FADS2,WHRN,SH2B1,RIMS2,DOCK4,DBN1,EDNRA,SORBS3,DMTN,DLC1,CAMSAP1,PDLIM5,HBS1L,GCNT2,GNAS,STON1,PCLO,GUCY1A2,KCNJ3,MEF2C,MYT1,NF1,NNAT,NOS1,PDE4A,GRAMD1C,FAM120C,KCTD17,ZFHX4,RPS6KA2,SELL,PPP1R9A,SLC1A7,PEX26,SLC9A5,ZHX3,ZNF423,ARHGAP26,SPTAN1,CLSTN2,MAPK8IP3,CEP68,RGL1,PHLDB1,SEMA4A,DMXL2,DOCK9,ZKSCAN5,HIRA,EMSY,TIGD6" Drug 6519_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ARID1A,ADCY6,AK2,SYT13,APC,APOC1,ASPH,NUMB,ADAM15,SYNJ2,CAMK2G,DLGAP1,EPS15L1,SULT4A1,HOMER3,CNTNAP2,RUSC2,DMPK,TRAPPC9,RCAN1,EDN3,HEYL,EFNA3,TNK2,FHL1,FOXG1,FYB1,GCNT2,GPER1,SLC2A6,HAS2,MBD1,MSI1,ADAM22,MYO7A,NEUROD1,SLCO1C1,RETREG1,NECAB2,PPP2R2B,PPP5C,PTPRB,TRIM68,KCTD17,TCP11L1,RPH3A,SLC15A2,SNCA,DDN,TRIM2,HIF3A,TEK,TK2,VIPR2,WIPF1,LAT2,SLC30A3,WNK1,STMN4,PLSCR4" Drug 6492_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "CDC42BPA,KCNAB2,GAS7,PPP4R4,ARHGDIG,CDK13,ATP1A2,ADAM23,BAIAP3,ZFYVE9,IFFO1,GREB1,RIMS2,DAPK1,HP1BP3,KBTBD11,RCAN1,DTNA,EFNB3,CELSR3,MBNL2,TENM1,ELAVL3,KCNMB2,VPS26C,FGF13,FYN,GAB1,GALC,ATP8A2,C1QL1,POLL,RASSF8,ITIH2,MYH7,ODF2,OLR1,GPR85,PPP5C,SAMD9,RASGRF1,GSTCD,CCDC102B,KCNIP1,MRAS,FRMPD1,ARHGEF40,RIMS1,ZCCHC24,ZHX3,ATP10B,PHLDB1,SYT5,PHF24,PCDHA5,HIF3A,PARD3,OSBP2,CLIP2,NSD2" Drug 4666_UP Probucol [23288-49-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "DPF1,SLC12A5,ADRA1D,LTBP4,CDK10,SEMA4G,ATP2B2,ADGRB2,SYNJ2,IL33,CACNA1A,CALB2,NEURL1,ARHGAP33,ADGRG1,SOCS6,DNAJB5,COL9A3,PLCH2,AK5,DPH1,ZNF391,PIPOX,EZH1,ABCA8,CACNG2,PRELID3A,GLYR1,STON1,GRM7,GUCY1A2,ATXN2L,HLF,ICA1,KCNF1,KCNJ5,KCNMA1,KIFC3,LMO2,VWA5A,NF1,NPTX1,P2RX7,PDGFRA,KCTD17,SELL,MRAS,SLC1A7,KANSL3,SLC12A4,LIMCH1,KDM4B,TROVE2,PHLDB1,PLCB1,TGFBR3,ZNF34,TNS1,VGF,KCNAB1" Drug 4633_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.15E-07 1.06E-02 7.48E-06 8.51E-05 60 199 "ARID1A,TRMT9B,MADD,PDE8B,ASTN1,CADM3,KIF1A,BAIAP3,LDLRAD4,SYNGR3,LARGE1,CABP1,COL9A3,SLC4A8,CREB5,CNTNAP2,KIAA0513,MFAP3L,SPOCK3,SGSM2,CHRDL1,DMPK,ST8SIA3,CELSR3,PHF20L1,MRNIP,STX2,EZH1,NRN1,SCARA3,FOXG1,ANKFY1,FAM49B,GART,GFER,MSL3,HNMT,SCIN,KIF2A,MEF2C,NEUROD1,NNAT,PCDH9,GRAMD1C,GON4L,PTN,ZSCAN2,TMEM231,ZFP30,ASAP3,AMBRA1,LIMS2,SLN,EMC1,KAZN,EXOC7,TPM2,SF1,MAP3K12,EPM2A" Drug ctd:C076029 olanzapine CTD 2.16E-07 1.06E-02 7.50E-06 8.53E-05 42 121 "SERPINA3,APP,AQP4,PDE8B,C5,CAMK2A,DCLK1,NUMBL,CHRM1,CLU,ABCG2,CP,NCAN,DRD1,NPTN,GAD1,GAD2,PPARGC1A,RAPGEF4,GRIA2,HMGCR,HTR2A,ITIH2,JAK2,KCNA1,KCNH2,KLC1,MAOB,MAP2,NPY,PDE1A,ABCB1,SERPINI1,PLP1,RELN,RGS7,KCNIP3,SNAP25,SYPL1,VLDLR,KCNAB1,RTN4" Drug ctd:D003010 Clorgyline CTD 2.20E-07 1.08E-02 7.62E-06 8.67E-05 53 168 "ADRB2,APC,ZBTB10,DST,CACNB2,CLGN,CHM,NIPBL,PHF14,ZFYVE16,MBNL2,NSRP1,PPP1R1B,POLK,RGPD5,STAG2,GAP43,GK,ZNF638,GOLGB1,RAPGEF4,ATG4C,KTN1,LIG4,MAOB,CHIC1,MIA2,CPNE9,MYO6,NFE2L2,CNTN3,PIK3C2A,SAMD9,VPS13C,ZNF493,ARID4A,REV3L,CLIP1,CCDC112,CHD9,PREX2,BDP1,VPS13A,ANKRD12,STXBP4,TBC1D15,RICTOR,TCEAL7,ZNF138,FZD3,KLHDC1,CBLN2,SENP7" Drug 7387_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.29E-07 1.12E-02 7.93E-06 9.03E-05 55 177 "MTUS1,SHROOM2,ARNTL,MARK4,ST3GAL5,USP2,WHRN,PDE4DIP,CTH,RIMS3,DNAJC6,PLPPR4,EFNA3,RGS17,TAOK3,ATP8A1,TESK2,FGF13,BAIAP2,DPYSL4,SORBS1,FYN,RND1,GLS,GUCY1B1,DIPK1A,KIF5C,VWA5A,MATN3,KITLG,TAGLN3,PCDH9,PDGFRA,SERPINI1,PRPH,SYTL2,RAB3A,ENOX1,RGS4,RPS6KA2,SH3GL3,ASAP3,DOP1A,TNIK,ZCCHC24,ARHGAP26,SPTAN1,THSD1,RGL1,SYT11,SYT1,SSBP2,DNAJC12,TRIM9,PLSCR4" Drug 1785_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "ADCY2,APAF1,ASPH,WASF1,LDLRAD4,HIP1R,RUNX1T1,LRBA,RAB26,AATK,OSBPL3,PDE4DIP,DOCK4,C2CD2L,GSDME,DTNA,ANKRD46,FAM13A,MBNL2,LPAR6,MRNIP,EPS8,ACSL4,KAT8,GABRA4,GLS,GOLGB1,PTPRT,ACOT7,IDH3A,KIF5C,MEF2C,NCAM1,SLC11A2,NRGN,NTRK3,GPSM2,PRKACB,MAPK10,DEF8,PTK2,RAD51D,RGS12,MYH14,SATB1,PPM1E,NTNG1,SLC1A7,SPART,SS18,MCF2L,TBL1X,TCF4,UCHL1,FLRT2,TRIM9,GDPD5,ST7,SMIM8" Drug 4781_UP Benperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "ACHE,AMH,SPTBN4,BRINP2,ATM,ATP2A2,KSR1,SYNJ2,BAIAP3,CFAP410,STOML1,COL9A3,CPS1,CSF1,OSBPL3,PHYHIP,SPOCK2,CTIF,CNIH3,SGK2,EFNA3,TNK2,C3orf18,MTSS1L,ERCC2,ZNF589,FGFR1,DLL3,FYN,DKK3,GAD2,DISC1,GCNT2,GSN,GUCY1A2,HPCA,KCNH2,MBD1,MOBP,NF1,NPTX1,EPN1,MAPK7,ZSCAN32,EMID1,RYR1,ASAP3,WDTC1,PEG10,ST5,AJAP1,PLCB1,EXOC7,WSCD1,DOCK9,CABIN1,ZIC3,PHTF2,NLRP3" Drug 4224_DN Benzocaine [94-09-7]; Down 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "MTUS1,PLA2G6,SHROOM2,PDE8B,MARCH3,MAP7,CHM,CLCN4,IQCK,CREM,ENTPD4,FAM169A,TBC1D5,DAPK3,DNAJC6,MFAP3L,RUSC2,PLPPR4,CHRDL1,EXOG,FCF1,EPHA5,ETV1,RRAGB,ST3GAL6,FGF1,FOXG1,TRMO,PNMA2,GLI2,PCLO,HNMT,DIPK1A,INPP5B,JAK2,LIG4,TAGLN3,PAK3,RETREG1,TMEM231,RAD52,BEND5,RGS10,PAQR6,MAPK12,MRAS,FBXO11,FNDC3A,SPTAN1,CDK19,IQCE,TCF4,ARHGEF12,TK2,WIPF1,NSD2,XRCC4,KCNAB1,PHTF2" Drug 3173_DN Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "C1QTNF3,MRTFA,DOC2A,APOC1,CDC14B,CDK10,SEMA4G,MARCH3,MARK4,RASL11B,ALDH4A1,SLC4A4,ATP6V0A1,BCL7A,SOCS6,AKAP7,CRY2,LRIG1,ATRNL1,SIPA1L1,CYBB,RABGAP1L,CNNM1,SORBS3,ENO2,ANKMY1,FGFR1,PRELID3A,GAB1,GABRA2,ZNF44,TDRKH,LPAR4,DHX35,KHK,MIA2,KITLG,NNAT,CNOT4,PDE3B,PLXNB1,PRKAR1B,ZCWPW1,SLC1A7,SLC20A2,WDTC1,CEP68,STX1A,VAMP1,SMG6,TNS2,CRTC1,ZNF34,THRA,CABIN1,TRIO,RUNDC3B,GDPD5,EPM2A" Drug 4657_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "NR0B1,PLA2G6,BRINP2,ATP2B2,ATP2B3,B3GALT2,ADAM23,ADGRB2,BMP7,USP2,SLC16A4,GPR37L1,ADGRG1,CHGA,CHN2,CHRNA4,RGS6,SUSD5,SV2B,DRP2,DTNB,APC2,ATP8A1,ERGIC3,FYB1,ALDH1L1,GLI2,GRIK3,SPACA9,IL1RAPL1,FICD,ITIH2,KIT,MT1M,MYCN,MYH7,NF1,NOVA1,PDE4D,POU3F2,GRAMD1C,CNNM2,PTPRH,C1orf54,ZMAT4,RFX2,RGR,PKNOX2,SLC6A9,CXXC4,ZHX3,NPAS3,ATP10B,SLC44A1,TLR4,SEZ6L,EPM2A,HRASLS,ST8SIA2" Drug 6224_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "ASPHD1,ACHE,ADORA3,AP2A2,APOC1,CDC14B,CAPRIN2,KIF1A,BMP7,CDK5R1,CACNB2,CAMK2B,MAGI1,FOXN3,ZFYVE9,CLCN3,ABI3BP,SH2B1,SIPA1L1,FAM169A,EDRF1,TBC1D5,ATN1,MBNL2,ING4,ANKMY1,ZNF589,FGF13,FHL1,SYT17,CNTRL,RNFT2,IL6ST,INPP5B,KCNF1,KPNA5,NEK1,NOS1,PHKG1,SERPINE2,RALGDS,RGS12,FAM192A,SYBU,LIMS2,SLC20A2,CEP68,STX1A,SEMA4A,TRIM2,GPR161,ZMYND8,ZBTB14,PRDM2,KCNAB1,MPPE1,NUP214,TIGD6,SSPN" Drug 4558_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "PLA2G6,MRTFA,AMT,EPB41L5,GAS7,CCDC181,ATP6V0A1,NEURL1,ASIC3,B4GALT6,NRG2,ENTPD4,SH2B1,SUSD5,CTNND2,SRGAP3,DTNA,EDNRB,SGK2,EIF4G2,OGA,FYB1,ERAP1,ALDH1L1,GLI2,IRAK3,HPCA,INPP5B,KIF5C,MAP2,AFDN,MYCN,PFKFB2,SERPINI1,DCHS2,PTPRH,RAB3IL1,CCDC40,RASGRF1,SLC6A15,RFX2,CCDC102B,MRAS,SLC1A6,KANSL3,SOX10,ZHX3,VAMP1,TRIM2,THRA,TK2,VIPR2,VLDLR,PRDM2,SLC17A7,KCNAB1,FAM13C,PHTF2,JPH3" Drug 4643_UP Iohexol [66108-95-0]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.37E-07 1.16E-02 8.17E-06 9.29E-05 59 195 "ADCY6,ADD2,AP2A2,MTUS1,SEMA7A,ARRB2,ATM,KSR1,C5,CACNA2D1,ARHGAP33,SOCS6,CHM,CHN2,RAB28,TPP1,RAB26,CSF1,RGS6,VCAN,PDE4DIP,PLPPR4,ARNT2,EDNRA,PLEKHO1,RASGRP2,ZNF589,PRRC2B,GPM6A,KIT,TAGLN3,CNOT4,PLCD1,RC3H2,PTK2,RAB5B,RFX2,TRAPPC13,IL17RB,FUZ,FBXO11,ANKRD6,ABLIM3,FAIM2,TNIK,ZHX3,BEX1,ARHGAP26,GSE1,SYT1,COBL,ASTN2,KIAA1107,TBCEL,TCF4,SSBP2,UGT8,KCNK12,NAV3" Drug CID000002531 calmidazolium chloride Stitch 2.58E-07 1.26E-02 8.87E-06 1.01E-04 51 160 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,AGT,PLA2G6,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CALM1,CAMK2B,CAMK2D,KRIT1,LRBA,MYL6B,HDAC4,DNAH9,PTK2B,CAMKK2,ATP2C1,GAP43,MYLK2,KCNN1,KCNN3,MYL3,NOS1,P2RX7,PDE1C,PDE1B,ENPP2,PENK,CAMKV,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PTK2,RNH1,SLCO1A2,CABIN1,TRPC3,CAMK1G,NUP214" Drug CID000066161 MAPS Stitch 2.61E-07 1.28E-02 8.89E-06 1.01E-04 58 191 "METAP1D,TAOK1,MYH7B,APC,SPTBN4,MARK4,ATP6V0A1,KIF1A,CALM1,MAP7,PRC1,DCLK1,BOC,DCTN1,DLX1,DNAH9,DPYSL2,EML1,TUBD1,TUBA1B,TUBB3,TUBB4A,ACTL6B,TUBA8,GFAP,TUBA1C,STMN2,CIT,SYNPO,TUBB2B,KTN1,STMN1,MAP2,MAP4,MAP6,MAPT,MARK1,MBP,NEFM,NEFH,PCMT1,ENPP2,PLEC,FSD1,PTPA,KANSL1,CLIP1,SPTAN1,SPTB,SYN2,SYP,ACTR6,NEIL2,TUBB2A,TUBB1,ANKS1B,LRP8,TUBA1A" Drug 6836_UP Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "MRTFA,BIN1,APOC1,AQP4,ASPH,SLC4A4,SLC2A11,CACNA1A,CD86,ARHGEF2,RCBTB2,AKAP7,RCHY1,NCOR2,ATRNL1,VCAN,DCAF4,SNPH,RUSC2,ATN1,DUSP9,EFNB3,RASGRP2,ZNF391,ANKMY1,REEP2,ACSL4,DLC1,NSG1,GAB1,SIGLEC8,ALDH1L1,PCDH17,GNG3,GRIK5,AP4S1,KCNC1,KCND3,KCNMA1,AFF1,MMP16,TAGLN3,CAMKV,MTRF1L,DIRAS2,MYH14,RASA3,PPP1R9A,ASAP3,SLITRK3,FAM214B,SLC14A1,KIF21B,MAPK8IP3,ARC,WSCD1,TPM3,UCHL1,VIPR2,SYNC" Drug 6766_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "C1QTNF3,AMPD3,DNAH17,ALDH4A1,BCL2L2,CFLAR,CACNA1I,BAIAP3,CA4,CD86,ARHGEF1,DNAJB5,GREB1,DCAF4,SNPH,DBN1,ZNF804A,DUSP9,PLXNC1,FGF13,FGFR3,HPCAL4,GPR153,ERAP1,RND1,TDRKH,STON1,GRIK5,CACFD1,DHX35,KCND1,MAP4,MAPT,MEIS1,MIA2,AFDN,MMP16,TAGLN3,NDUFA5,OPRL1,PDE1C,PFKFB2,LRP12,RELN,RAB3IL1,MYH14,SH3BP2,PPP1R9A,SLN,SNCA,SOX2,ZCCHC24,IQSEC2,TSPYL2,PHLDB1,VAMP1,WSCD1,CUX2,TK2,TRPM2" Drug 604_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "GRAMD1B,PLA2G6,APAF1,APC,PDXK,ARNTL,CADM3,N4BP2L1,AZGP1,BAIAP3,CCK,CDH18,CHN2,HOMER3,CRMP1,SDC3,DCAF4,DCAF8,GIT2,DBT,JAKMIP2,SIDT2,SUGP2,ING4,KIAA1109,GNAO1,GNG4,ATXN2L,IGSF1,ITIH2,KCND3,KIFC3,PIK3CD,PPP2R2B,PPP3CA,PRKAR1B,PRPH,PLPPR1,RGS3,RNASE1,TCP11L1,FAM192A,ZNF821,ITSN1,FAM214B,ELMO2,USP33,ZSWIM8,NMNAT2,COBL,EXOC7,TMEM151B,TNS2,CRTC1,RBFOX2,SEZ6L,CHST5,TRIO,VAV2,WNT7A" Drug 5532_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ARID1A,AGT,SEMA7A,PPFIA3,SEMA4G,PRX,DNAH17,BTRC,CA12,ARHGEF2,CLGN,CRLF1,CHN2,STOML1,AKAP7,C2CD2,CSF1,ARHGEF10,EDRF1,GSDME,SLC12A6,HEYL,MBNL2,CDKL3,FGFR1,FHL1,GPR153,GABRA1,ERAP1,MYOZ2,KHK,LIG4,MDM4,NF1,NPPA,PDE4D,PDPK1,PHKG1,SERPINI1,NLE1,STRN3,LRP12,PPARA,RGS7,RPS6KA2,SCN2B,SEC14L1,SLC2A5,KIF21B,KDM4C,ARHGAP26,CEP68,KIAA0930,CRTC1,TK2,LMF1,LAT2,KCNK12,MKRN3,PHTF2" Drug 6415_DN Orlistat; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ADORA1,ADRA1D,ADGRF5,SEMA6A,TRMT9B,APLP1,PRX,SLC4A4,GYG2,ARHGEF1,CDH18,TAOK2,RGS6,CNTNAP2,SEC14L5,RIMS3,DBN1,DCT,PARD6A,SIDT2,ANKMY1,F5,DLC1,OLFM1,AGAP2,FYB1,FYN,ZNF276,ATF7,ICA1,C2orf72,TJAP1,MAP2,ZNF862,NF1,PALM,PC,PIK3CD,SNRK,PTAFR,RAB3IL1,RPS6KA2,ASAP3,BCAN,SLC6A11,ZCCHC24,PEG10,CDK19,SS18,MAPK8IP3,ARC,ASTN2,POPDC3,SIN3B,SYNE1,TRPC1,TUBB1,UGT8,SYNC,KCNAB1" Drug 3682_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ASIC1,ARID1A,ADCY6,ALK,MRTFA,BEGAIN,APAF1,PPFIA3,BAIAP3,CAMK2B,SEPT7,B4GALT6,TAOK2,PLAA,IQCK,ENTPD4,SLITRK5,C2CD2L,PLPPR4,CDON,ATN1,CNNM1,PLEKHO1,LRRC23,ETV1,FGFR1,PRELID3A,PCDH17,GPR19,SPACA9,GRIK5,CACFD1,RASSF8,ATXN2L,KCNMA1,KHK,MAPT,GIT1,OPRL1,PENK,PFKFB2,CEP41,PRKAR1B,PEX5,RAP1GAP,RGS10,SBF1,SCN8A,LIMS2,PKNOX2,RAB3GAP1,SLN,FNBP1,SP4,COLGALT2,DNMBP,CDK20,VLDLR,ZNF45,TFIP11" Drug 7204_UP Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ADORA1,ADORA2A,BIN1,ANK1,APAF1,APBB2,GAS7,ARRB1,MARK4,ATP6V0A1,GYG2,CACNA1I,LDLRAD4,CHGA,CHM,B4GALT6,SLIT2,SULT4A1,AKAP7,RCHY1,BAG4,NCOR2,SLC12A6,DTNB,MBNL2,LRRC23,SPEG,F5,FGFR1,ANKFY1,DOT1L,OGA,FYB1,GPD2,ADAMTS13,GRM8,SYNPO,IL6ST,KIFC3,LIG4,KITLG,MSI1,MYCN,ENPP2,TMOD2,NECAB2,PRKAR1B,PRPH,ELOVL2,SH3BGR,ASAP3,SLC6A9,SLCO1A2,WDTC1,TTBK2,EXOC7,DMXL2,TRIM2,DNALI1,MVB12B" Drug 2434_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ADCY6,AGT,FAM135A,BEGAIN,BIN1,CNTNAP1,APBB2,MPDZ,SYNJ1,CALB2,CHN1,CHN2,STOML1,ABCG2,CSF1,ARHGEF4,PARD6A,SPOCK3,ST8SIA3,SORBS3,ELN,EIF1,DLC1,PDLIM5,TRAF3IP2,RUNDC3A,GPM6A,GPM6B,ATF7,PCLO,GRIK5,GRIN1,ATXN2L,SYNPO,IL12A,KCNJ5,KCNMA1,KIF5A,LMO1,PLCD1,PPP2R2B,WDR25,PTN,RGS12,ZFHX4,MYH14,MAP6D1,SHANK2,TNIK,HECW1,ATP10B,MAPK8IP3,KANK1,TCF7L2,NSD1,TRIO,TRPC3,ZMYND8,VGF,SLC17A6" Drug 6701_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "MRTFA,PKP4,APBB2,APC,AQP4,SCAPER,IL33,BTRC,KALRN,CACNA2D2,B4GALT6,JAM2,TAOK2,CLCN4,CRMP1,HAPLN1,MICAL2,DCT,EXOG,DTNA,HIPK3,EFNA3,EFNB3,ZNF589,FGF1,EFCAB2,CAMKK2,ERGIC3,ATXN2L,SCRG1,ITPKA,KCNMA1,ARHGAP12,PACRG,SMAD1,KITLG,MX1,MYL3,NASP,CNOT4,NOVA2,OPRL1,PDE4A,PFKFB2,ELOVL2,RGS4,SELL,SH3BP2,SNCA,ZNF423,ARHGAP26,ASTN2,TAL1,PCDHA5,KCTD2,R3HDM1,TPM1,TPM3,ZNF24,ZNF225" Drug 6521_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ADCY6,TRMT9B,OGT,APOC1,BCAS1,PPFIA3,SEMA4G,MARK4,CFLAR,ST3GAL5,CACNA1D,CDH8,CDH10,CHRNB2,PLAA,QKI,WHRN,AATK,EDRF1,KIAA0586,GIT2,MFAP3L,KIAA0753,RABGAP1L,DLG3,SIDT2,ENO2,STX2,CDKL3,F3,C1orf61,EFCAB2,GLS,CNTRL,SPACA9,HNMT,HSD17B1,ITPKB,VWA5A,MAP4,MEIS1,FSD1,PPP2R2B,RAB3IL1,RNASEL,ZNF821,NLGN1,SHANK2,SS18,NXT2,EXOC7,WDR7,PSD3,CDK20,XRCC4,SYNC,MAP3K12,EMSY,MPPE1,UBE3B" Drug 4197_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "KIDINS220,C1QTNF3,SEMA6A,ASCL1,SLC4A4,SYNJ1,ST3GAL5,SCAPER,CACNA1I,CACNG1,CAPN3,SCARB1,CDC42,ARHGAP33,LARGE1,DNAJB5,IFFO1,ABCG1,RIMS3,ECM2,EDN3,HIPK3,EFNB3,TNK2,LRRC17,EPHB1,NRN1,OLFM1,CAMSAP1,HBS1L,GALC,GAP43,DISC1,GNG3,TDRKH,AP4S1,NXPH3,PTGDR2,KCND3,KCNJ4,LAMA2,MYH3,NOS1,PAH,PDE3B,PLCD1,PTPRN2,GAL3ST4,RFX2,EMID1,SLCO1A2,OGDHL,KIF13A,TSNAXIP1,SYN2,TK2,TPM1,TRPC3,PRDM2,KCNAB1" Drug 4202_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "AP2A2,ALAD,ALK,AMPH,APAF1,APC,CACNA2D1,HAP1,CAMK2B,SCARB1,ENTPD2,RAB33A,NRXN1,TPP1,DNAJB5,HOMER3,ABCG1,PDE4DIP,SPOCK2,DBT,MAGI2,EFNA3,EFNB3,KCNMB2,ETV1,ZNF589,DCTN2,TRMO,PDLIM5,HBS1L,B4GALNT1,GAP43,DISC1,PADI2,PTGDR2,ATXN2L,KLF12,KCND3,MEF2C,LYRM9,NF1,SETD4,CAMKV,SPATA6,LRRN3,PPP5C,PKN2,ELOVL2,PTPRN2,RAD52,GAL3ST4,RGS4,RPRD1A,TCP11L1,NTNG1,PREX2,ARHGEF40,SLC14A1,TNIK,RPGRIP1L" Drug 2814_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "NDRG2,PLA2G6,CDC42BPA,KCNAB2,APC,PPFIA3,PLA2G4C,DNAH17,BRINP2,SLC2A11,ADAM23,KSR1,SCAPER,KALRN,HIP1R,CACNA2D2,ASIC3,CHRNB2,HOMER3,NECTIN3,CSF1,NOS1AP,ERBB4,FGF12,CAMSAP1,DLL3,TMEM8B,GFER,RND1,GRIK3,GSN,ELOVL5,IL6R,KCNQ3,MMP16,LYRM9,CLDN11,SNTG1,GPR85,PLCD1,PPP5C,PTCH1,PTPRO,RAB3IL1,BCAN,DZIP1,SLC1A2,LIMS2,ATP10B,AJAP1,POPDC3,SEMA4A,TBCEL,SLC44A1,CABIN1,LAT2,SLC13A3,XRCC4,DNALI1,SEMA3B" Drug 6837_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "APLP1,ASCL1,PDE8B,ALDH7A1,ADAM23,CALB1,USP2,ARHGEF1,SLIT2,RCHY1,TCEAL2,BAG4,PDE4DIP,SMG7,DMPK,DTNA,DTNB,DUSP9,HIPK3,MBNL2,MRNIP,LRRC23,KCNMB2,REEP2,KAT8,CAMSAP1,GAB1,ZNF44,TMEM8B,GPER1,SPACA9,GRM2,HRH3,HNMT,KCNN2,KITLG,MYO7A,NEK1,PDE1C,MTRF1L,PTHLH,KLHDC8A,TCP11L1,SCN8A,ASIC4,ITSN1,PPP1R9A,DOCK10,FBXO11,LIMS2,SHANK2,KDM4B,ZCCHC24,SPTB,SZT2,TNS1,TPM2,HIRA,VLDLR,LMF1" Drug 6405_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.61E-07 1.28E-02 8.89E-06 1.01E-04 60 200 "ARID1A,NDRG2,APBA2,APC,BCAS1,SEMA4G,ATP1A3,BAIAP3,CFAP410,CAMK2B,USP2,CDO1,ASIC3,ZFYVE9,SULT4A1,CNN3,SH2B1,VCAN,CNTNAP2,SDC3,RIMS2,DAPK3,SPOCK3,USH1C,ERCC2,FAM198B,CACNG3,HPCAL4,CGREF1,GABRA2,GAD2,ATP8A2,RUNDC3A,GLS,IFI16,KCNN1,SMAD1,MGAT3,MMP17,BCO1,MYT1,NPPA,PENK,PURG,SPATA6,MAPK8,SNRK,TMEM206,SLC1A7,SNCA,KDM4B,INKA2,PHLDB1,TAC3,WSCD1,TCF4,ZEB1,FLRT2,SLC17A7,PLSCR4" Drug CID000001233 ibotenic acid Stitch 2.80E-07 1.37E-02 9.52E-06 1.08E-04 42 122 "ACHE,BCHE,CA4,CALB1,CCK,CHRM1,CLCN3,CLCN4,DRD1,EEF1A2,PPP1R1B,GAD1,GAD2,GFAP,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4K5,MAP4,KITLG,NPY,PDYN,PENK,GPSM2,POU6F1,SST,SYP,VIPR2,PORCN" Drug CID000001678 3-nitropropionic acid Stitch 2.81E-07 1.38E-02 9.56E-06 1.09E-04 55 178 "ADORA1,ADORA2A,ADORA3,APAF1,KCNAB2,ATP2B1,CACNA1A,CACNA1B,CALB1,SLC25A14,KYAT1,CNR1,SLC25A27,HDAC9,DYNC1I1,ATN1,PDCD6IP,FCF1,AASS,EN2,ENO2,PPP1R1B,FOXG1,GAD2,GFAP,PPARGC1A,TCERG1,GRIK1,GRIN2C,GRIN2D,PACSIN2,HP,HPR,HSP90AA1,IGF1,MAP2,OGG1,PAH,PENK,ABCB1,PACSIN1,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A2,SLC1A3,SNCA,JMJD6,ABCC8,PRTFDC1,STMN4,SLC17A7,KCNAB1,JPH3" Drug 1047_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.86E-07 1.40E-02 9.59E-06 1.09E-04 57 187 "ABHD6,ADD3,CDC42BPA,CDC14B,CAPRIN2,BMP7,ST3GAL5,RAB29,WASF1,SYNGR3,UBE2L6,FOXN3,NMT2,RUBCN,KIAA0513,KIAA0586,ARMCX2,TSPAN5,OPTN,EFNA3,EFNB3,STX2,EXTL2,ARMCX1,FAM49B,GPR153,CSPG5,FYN,WASF3,KCNMB4,GRB10,KHK,KIF5C,MAPT,MITF,MPP2,MXI1,OGG1,PDE4A,PIK3CD,RETREG1,PRPH,PTCH1,SUSD4,MORC4,PPM1E,FBXO11,SYBU,CCDC88A,ZCCHC24,ELOVL4,STXBP1,SIN3B,TRIM2,BEX4,DNAJC12,NDRG4" Drug 6670_DN Brinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ARID1A,PLA2G6,TRMT9B,AMPD3,GAS7,BCL2L2,MYRF,CACNB2,ARHGAP33,SOCS6,NRXN3,IQCK,ABCG1,CSF1R,CSNK1E,CNTNAP2,SLITRK5,ARHGEF4,RIMS3,CNIH3,RABGAP1L,FEM1B,CELSR3,PLXNC1,MTSS1L,ERCC2,ZNF391,ETV1,KIAA1109,BAIAP2,FAM49B,ZNF44,GAD1,B4GALNT1,ERAP1,HLF,LSS,MAPT,MEIS1,N6AMT1,NF1,CNOT4,PLXNB1,MAPK7,SYTL2,PTN,ZCWPW1,ROM1,NEK11,ZNF671,SCN8A,PPP4R3A,TBCEL,SLC44A1,TIAM1,VIPR2,SEMA3B,PHTF2,TIGD6" Drug 3187_DN Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "KIDINS220,AK2,MRTFA,TRMT9B,AMPD2,CDC42BPA,APC,CDK10,SEMA4G,ATP6V0A1,RIPK1,CDK5R1,SCAPER,CAMK2G,TAOK2,AKAP7,CREM,AKAP12,DNAJC6,SIDT2,EFNA3,FGFR1,ANKFY1,ZNF44,ERAP1,TXNL4A,GRM1,ITPKB,KCNH2,LMO2,MAP4,SCAMP5,CNOT4,NUMA1,CAMKV,SLC25A23,MINDY2,ZCWPW1,GSTCD,SBF1,SGK1,AMBRA1,SLC1A7,KIF13A,ST5,STX1A,VAMP1,MTCL1,MCF2L,DOCK9,TNS2,CRTC1,TK2,PLPPR2,VIPR2,MICAL1,WNK1,HPS4,C12orf4" Drug 5619_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "MARK4,SCAPER,MTMR3,GYG2,CAMK2G,CBFA2T2,B4GALT6,PDE4DIP,SDC3,RCAN1,DTNA,OPTN,EFNA3,TNK2,DENND4A,RRAGB,KAT8,KIAA1109,FGF12,FGFR1,BAIAP2,HBS1L,ALDH1L1,GLS,CACFD1,NR3C1,INPP5B,MAP4,LYRM9,NDUFA5,SERPINE2,RETREG1,LRP12,MED1,WDR25,FAM120C,BSDC1,SBF1,SH3BP2,ITSN1,EPN2,MAPKBP1,KDM4B,WDTC1,KDM4C,SPART,CLSTN2,THSD1,PLCB1,EXOC7,DMXL2,KIAA0930,TRPC1,ZBTB14,ZNF45,SYNC,WNK1,SLC17A7,MARCH8" Drug 3031_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ADCY2,SPARCL1,BMP7,CACNA1D,KALRN,NGB,REPS2,CHRNA4,MICAL2,SUSD5,RIMS2,SEC14L5,FRMPD4,MAGI2,DSCAM,DYRK1A,EGFR,PLEKHA1,LRRC23,ATP8A1,FGFR3,BAIAP2,CAMSAP1,GABRA1,GABRG2,GAD1,GALC,B4GALNT1,SIGLEC8,ADAM28,RUNDC3A,GLRB,PRUNE2,GRIA4,CACFD1,GRM7,PTGDR2,KCNJ9,KCNN1,ADAM22,MYH3,NPY,PDE1C,FSD1,PSD,PTPN13,PTPRN2,TCP11L1,MAP6D1,KCNIP2,PKNOX2,SOX2,IZUMO4,UNC5B,SPTB,TBCEL,CHST8,CRB1,AP4E1" Drug 4970_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "NDRG2,NME5,SPARCL1,BIN1,CDC42BPA,APLP1,SEMA4G,SLC2A11,CDK5R1,SCAPER,CFAP410,CACNB2,CACNG1,CAMK2B,SLC16A4,STOML1,HOMER3,SLC4A7,CSF1R,ARHGEF10,RIMS3,DMPK,EDNRB,HIPK3,SIDT2,ING4,FAM198B,TUBB4A,KIAA1109,FGF13,FOXG1,CGREF1,GPR153,GAB1,GAD2,GLYR1,ADAMTS13,GSN,KCNN1,NNAT,P2RY1,GDPD2,PTAFR,ELOVL2,CARF,RPS6KA2,SH3GL3,PKNOX2,ARHGEF40,SLN,NPAS3,AJAP1,PLCB1,PSD3,TGFBR3,RIMBP2,CABIN1,TRIO,AMACR" Drug 2778_UP Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ALCAM,PPFIA3,APP,BRINP2,BACH1,SYNJ1,CFAP410,CACNA1D,CACNA2D1,CACNG1,CBFA2T2,CNTN1,CABP1,SH2B1,CSF1R,CNTNAP2,DOCK4,RIMS3,KBTBD11,DYRK1A,PLXNC1,LRRC23,KIAA1109,FHL1,IQCG,GPM6A,GPR22,GPER1,TJAP1,IL6ST,JAK2,MAN2A2,MAP4,MSI1,NF1,NRGN,SNTG1,GPR85,POLG,POU3F4,PRKAR1B,MAPK8,MAPK10,ZNF493,ZDHHC14,KCTD17,ZFHX4,RPS6KA2,KCNIP1,LIMCH1,ZCCHC24,KDM4C,MAPK8IP3,ELOVL4,ATP11A,TK2,PARD3,PRDM2,PHTF2" Drug 2969_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "NDRG2,ADORA3,CDC42BPA,ANK3,APBB2,STX16,BCL7A,C5,CAPN3,NEURL1,CLCN4,SLC4A8,RCHY1,CSNK1E,VCAN,EXOG,MBNL2,RASGRP2,F5,KAT8,SEMA4D,RAB40B,LILRA2,IL6ST,IPO5,MDM4,AFDN,PIK3R1,PLCD1,PLCL1,PKN2,PTAFR,RAB3A,RET,SEMA6D,ST6GAL1,CCDC92,ANKRD6,DHX30,SLC11A1,PALLD,ZHX3,DBNDD2,SPTAN1,TROVE2,FCHO1,ATP11A,EXOC7,CAMSAP2,TCF4,PSD3,OBSL1,SLC44A1,TJP1,TMPO,TNS1,FLRT2,SLC13A3,ZBTB16" Drug 3374_UP Aminophylline [317-34-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ADCY6,ADORA2A,ADORA3,KIDINS220,SEMA6A,LGR5,DNAH17,CA4,HIP1R,CDH8,CHI3L2,PLEKHB1,CHRNB2,NMT2,COL9A3,CSF1,ARHGEF4,RIMS2,ST8SIA3,MBNL2,EGR3,AASS,ERBB2,TUBB4A,DLC1,FGFR1,FHL1,GAD1,NEU3,ALDH1L1,RUNDC3A,GPER1,GPR37,GRIK5,LAMA2,MEF2C,MGAT3,AFF1,PDGFRA,CDIP1,NECAB2,LRRN3,FAM120C,KLHDC8A,SATB1,SELL,SORCS3,CDK19,ATP10B,NCDN,PCDHGA10,THRA,HEY2,R3HDM1,TPM2,PRMT8,LAT2,SLC30A3,KCNAB1" Drug 4808_UP Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "RALGAPA1,C1QTNF1,LTBP4,APBA2,KCNAB2,APLP1,CFLAR,BAIAP3,BTRC,CA4,CACNA1A,ENTPD2,ARHGEF2,DNAJB5,CNTNAP2,GREB1,TMCC2,DSCAM,EFNA3,PIPOX,ZIC4,FER,AFF2,EFCAB2,HTATSF1,POLL,GNAL,GNAS,LPAR4,GRIN1,KCND3,NUMA1,OCRL,SNTG1,PALM,CDIP1,PMS2,PTHLH,PTH1R,ZFHX4,FOXRED2,ITSN1,FRMPD1,SMTN,SLC6A8,SLC20A2,SLN,SMARCD3,RBM26,THSD1,POPDC3,EXOC7,IQCE,WSCD1,CRTC1,TRPC1,ZMYND8,ZNF24,KCNAB1" Drug 5226_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "KIDINS220,NME5,SEMA6A,ANK2,DGKD,APP,ASPH,SLC2A11,CFAP410,CACNA1A,KALRN,USP2,CDH2,CDH8,ARHGAP33,CHRNB2,SULT4A1,CNN3,ATRNL1,SIPA1L1,SDC3,RUSC2,SRGAP3,CDON,DRD1,SGK2,EFNB3,DMTN,RASGRP2,EZH1,KHDRBS3,HBS1L,MSL3,GRIK5,SLC2A6,RASSF8,ADAM22,NNAT,SERPINE2,SLC25A23,SAMD9,RAB3IL1,RALGDS,KLHDC8A,NEK11,RPH3A,KANSL3,ZCCHC24,RBM26,PHLDB1,TACR1,ARHGEF12,PCDHA5,TMPO,AMACR,TRPC1,MICAL1,KLC2,TIGD6" Drug 7186_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ADCY6,C1QTNF3,MRTFA,APC,SEMA4G,ASPH,ATP2B2,CFLAR,CDK5R1,CA12,SCARB1,MAGI1,DNAJB5,AKAP7,PDE4DIP,FAM169A,RIMS2,DBN1,DNAJC6,MFAP3L,ATN1,RCAN1,DTNA,SORBS3,DMTN,BAIAP2,SEMA4D,ANKFY1,DPYSL4,TXNL4A,KCNMB4,CACFD1,RASSF8,IGSF1,KCNJ3,LIG4,NOS1,CNOT4,SLC11A2,PDE4A,PRPH,GON4L,ATG16L1,RXRA,PPP4R3A,PKNOX2,MAPKBP1,SPTAN1,PHLDB1,PLCB1,SEMA4A,EXOC7,THRA,TMPO,PIK3R5,NPL,VIPR2,WRN,SSPN" Drug 7360_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ASIC1,AP2A2,ALCAM,APC,CDK13,CFAP410,CBFA2T2,SCARB1,COL9A2,HDAC4,GIT2,SPATA2,DTNA,EFNA3,RBM12,EFNB3,EPB41L2,DMTN,CDKL3,FGFR1,TRMO,GPR153,TRAF3IP2,GLYR1,GRB10,IL6R,KCNH2,LMO2,MBD1,MPP2,NFYA,STRN3,MAPK8,LRRC49,RIPOR1,RAB3A,ATG16L1,ZCWPW1,GSTCD,NEK11,FBXW7,EMID1,SEC14L1,ZFP30,SH3BP2,FRMPD1,PPP4R3A,CDK19,CLSTN2,ELOVL4,ARHGEF9,MCF2L,EXOC7,SZT2,AHCYL2,TRIO,TRPC1,VAV1,KCNAB1" Drug 5670_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ADCY6,ADRA1D,FAM131A,CDK13,ALDH4A1,BCL2L2,BCL7A,CFLAR,BTRC,CA4,CLGN,AKAP7,SLC4A7,PDE4DIP,GPRASP1,JAKMIP2,MFAP3L,SMG7,CDKL3,FAM198B,TRAF3IP2,GALC,AHDC1,GLS,HSF2,MATK,MDM4,ADAM22,NEK1,NF1,SETD4,LRP12,PRODH,GON4L,TMEM104,PTHLH,ZSCAN32,RAD51D,MSANTD2,RGS3,SH3BGR,ZNF365,FAM168A,ASTN2,SEMA4A,RPGRIP1L,TMOD1,RUNDC3B,TRPC1,FAM155A,VGF,MICAL1,ZNF74,WNK1,PRDM2,GDPD5,MVB12B,SMIM8,GAN" Drug 2862_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ASIC1,ARID1A,PLA2G6,AMPD3,PPFIA3,CFLAR,GYG2,CACNB2,CDC42,ADGRG1,SLC24A2,TPP1,TBC1D5,DNAH9,DYRK1A,EDN1,C3orf18,KCNMB2,SPEG,ANKMY1,F5,DLC1,OLFM1,LYVE1,TDRKH,GRIK3,ADAMTS13,NR3C1,GRM3,ATXN2L,ICA1,IFI16,KCNJ5,MAPT,NDUFA5,OPCML,CDIP1,PPARA,MAPK8,RELN,VPS13C,FAT4,TRIM68,KCTD17,SH3BP2,ASAP3,FAM214B,LIMCH1,DOK5,SP2,PEG10,VAMP1,SYN2,ZEB1,PARD3,FLRT1,LAT2,MKRN3,SYNC" Drug 7131_UP Ronidazole [7681-76-7]; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "APP,CFLAR,SCAPER,IL33,MAP7,CBFA2T2,ZFYVE9,TPP1,PCYT1B,PDE4DIP,DZIP3,GPRASP1,LYPD1,CDON,OPTN,TNK2,PLEKHO1,EPB41L1,ETV1,TESK2,BAIAP2,COPS8,KCNMB4,GUCY1B1,RASSF8,BACH2,HSF2,IL11RA,INPP5B,KCNN1,KIF5C,MAPT,SCAMP5,MMP16,NPR2,NUMA1,PC,PDGFRA,CDIP1,MAPK7,PTPRE,PTPRH,RAD52,UEVLD,MAPK12,PEX26,PPP4R3A,SLC6A9,ZNF667,EMC1,KDM4C,MAPK8IP3,PHLDB1,AHCYL2,ZFPM2,NSD2,ZNF74,SCG2,RNF170" Drug 3692_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "SEMA6A,CDC14B,ASTN1,N4BP2L1,BMP7,FUBP1,CACNA1I,CBS,CHM,CHRNB2,NRXN3,SULT4A1,PCYT1B,COL9A3,HAPLN1,ABCG1,CSF1R,CNTNAP2,NOS1AP,C2CD2L,ATN1,HIPK3,RGS17,EPHA5,KCNMB2,IGSF6,DLC1,ZNF589,KIAA1109,ANKFY1,SYT17,GFRA1,GRIK2,HMX1,SCIN,ITPKA,KCNJ5,KCNN1,MEF2C,MOBP,CD200,NNAT,FSD1,PTPRN2,SUSD4,S100B,SLC6A11,ARHGEF40,ELMO2,CXXC4,SPP1,SYT11,PLCB1,SYT5,CRTC1,GPR161,TNS1,ZNF154,VPS35L" Drug 7213_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "AP2A2,AK2,AMH,GAS7,MARK4,PTCH2,ATP1A3,ADAM23,CFLAR,CACNA1I,CACNA2D1,CBFA2T2,CBARP,TPP1,WHRN,RCHY1,SDC3,SNPH,DAPK1,ST8SIA3,RASGRP2,IGSF6,TUBB4A,KIAA1109,AFF2,OGA,GABRA1,GFRA2,RUNDC3A,SPACA9,HPCA,LIG4,MDM4,MGAT3,AFDN,MMP16,NCAM1,NF1,PALM,SERPINE2,RETREG1,SAMD9,WDR25,PEX5,GAL3ST4,RGS12,TCP11L1,ZNF821,SH3GL3,FAM214B,ZNF415,ZCCHC24,CRTC1,TK2,NR2E1,TNR,FAM155A,EMSY,HPS4" Drug 6889_UP AG-012559 [369370-06-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "NDRG2,DOC2A,BIN1,PPFIA3,PRX,CFAP410,CACNA2D1,CACNA2D2,CNOT8,LHX2,ZFYVE9,STOML1,PHF14,DCAF4,CYBB,RASSF2,ATN1,DSCAM,MBNL2,APC2,F3,CGREF1,POLL,CNTRL,GRIK5,CACFD1,HNMT,KCNH2,L1CAM,MATK,GIT1,ADAM22,ZNF862,NDUFA5,PALM,PDE3B,PDE4A,SLC25A23,LRP12,PRPH,PLPPR1,TMEM231,RGS12,ROM1,ZFP30,SH3BP2,KIF13A,TTBK2,KAZN,TCF7,OBSL1,SLC44A1,CHST5,HIRA,CADM1,LMF1,VSNL1,EVI5,MPPE1" Drug 6169_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "PLA2G6,CDC42BPA,FGD2,ASTN1,DDX3Y,SLC4A4,MTMR3,BTRC,RHBDL1,SLC16A4,CBFA2T2,ASIC3,CLCN4,FAM189A2,MICAL2,KLHL3,AK5,ATN1,DSCAM,OPTN,TNK2,SRPK3,VPS13B,F5,CHST15,OLFM1,GPR153,GAP43,CPLX2,PCDH17,LYVE1,GPR75,GPM6B,GPR19,KCNB1,KCNJ5,ADAM22,MYCN,MYL3,SLCO1C1,NPTX1,OPCML,PCDHGC3,PDE4D,RETREG1,EPN1,TMEM231,ASIC4,SLC11A1,SHANK2,SLCO1A2,KDM4B,ASTN2,PHF24,FAM189A1,TPM3,ZMYND8,VSNL1,NUP214" Drug 4402_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "C1QTNF1,LTBP4,MRTFA,DNAH17,CACNA1I,CFAP410,KALRN,BRSK2,HIP1R,RHBDL1,INA,TPP1,AATK,PHYHIP,AASS,TNK2,IGSF6,EFS,PIPOX,CORO2B,FGF1,HPCAL4,GAB1,GPR162,ADAM28,GRK4,GRM7,JAK2,LMO1,MAP2,MAPT,MEF2C,MMP16,MMP17,MN1,NOVA1,CAMKV,PIK3CD,EPN1,CDIP1,POU3F2,PROX1,PTAFR,ZFHX4,RYR1,SCN8A,SH3GL2,SLC8A1,ARHGEF40,SNAP25,KIF21B,ZC4H2,MLC1,FAM189A1,TRH,TRO,TRPM2,UBE3A,FAM13C" Drug 6624_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "PLA2G6,BIN1,APAF1,KCNAB2,BRINP2,ADAM15,ADGRB2,CFLAR,SYNJ1,FUBP1,ARHGEF2,ADGRG1,PLEKHB1,TPP1,DNAJB5,CNTN1,AKAP5,RCHY1,CRY2,CYBB,RIMS3,DLG3,HIPK3,MBNL2,ING4,ELAVL3,ETV1,VPS26C,ZNF589,FGF1,FGFR1,HPCAL4,GAB1,C1QL1,RND1,GPER1,GRM2,KITLG,CD200,NTRK2,PFKFB2,PFKFB4,CEP41,ELOVL2,ATG16L1,KCTD17,RYR3,STUM,ASAP3,HKDC1,PPP4R3A,SLC6A11,SLC15A2,ZC3H13,NACAD,PHLDB1,SMUG1,NSD2,ZNF74" Drug 3108_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ASIC1,AGT,FAM135A,PROM1,BMP7,FUBP1,GYG2,CAPN3,STOML1,RAB26,PICK1,SLC4A8,CPS1,ABCG1,CRYM,PDE4DIP,USP6NL,RIMS3,SPOCK3,SORBS3,BAIAP2,FOXG1,GPR153,FYB1,ALDH1L1,GCNT2,GRIN1,RASSF8,PADI2,KLF12,TJAP1,ITPKA,KCNMA1,KCNN1,AFDN,MPP2,NOS1,CLDN11,PFKFB2,PLCL1,MAPK3,MASP1,RASA3,FAM102A,SLC11A1,IZUMO4,ATP10B,ST5,PLCB1,ADGRL3,WWC1,DOCK9,PSD3,ARHGEF12,PCDHA2,TF,TGFBR3,KLC2,STMN4" Drug 6061_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ACTN2,ADRA1D,ADRA1B,AMPD3,BIN1,APLP1,ARHGDIG,SLC2A11,GYG2,CDH2,TAOK2,ARHGEF6,WHRN,IPCEF1,CHD5,CNTNAP2,SPOCK2,DYRK1A,SRPK3,HSD17B14,RASGRP2,APC2,CEND1,CORO2B,FYN,GFER,GNG3,STON1,GPER1,GPR37,GRM8,ATXN2L,ICA1,ITPKB,VWA5A,AFDN,SLC11A2,OPCML,NECAB2,LRRN3,RELN,FAM120C,CCDC40,RGS7,RGS12,KCTD17,KCNIP1,SLC1A7,PEX26,SLC9A5,LIMCH1,PEG10,JMJD6,SPX,TK2,ZKSCAN5,FAM155A,FLRT2,CLIP2" Drug 2318_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ARID1A,ADRA1D,C1QTNF3,SRPX,MRTFA,AMPD3,CDC42BPA,SEMA7A,APBB2,PPP4R4,CRLF1,RCBTB2,RAB33A,CRMP1,CSF1,CTH,EDRF1,DNAJC6,RCAN1,HSD17B14,STX2,ZNF589,FHL1,TDRKH,EML4,GRIK5,GRM1,ATXN2L,TJAP1,INPP5B,ITPKB,KCNN1,MMP16,GIT1,ZNF862,NF1,NTRK2,PALM,PPP5C,MAPK7,TCP11L1,FRMPD1,RPH3A,FAM214B,RCOR3,ZCCHC24,THSD1,SYN2,WSCD1,TCF7L2,AHCYL2,BHLHB9,CABIN1,VGF,WIPF1,CLDND1,XRCC4,PRDM2,SMIM8" Drug 3965_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ASIC1,NDRG2,APC,APP,PLA2G4C,MARK4,ALDH7A1,SCAPER,GYG2,FOXN3,CHM,B4GALT6,RAB28,CLTB,RCHY1,CSF1,EDRF1,TMCC2,CDON,SLC12A6,RCAN1,EDNRA,EFNB3,DLC1,ZNF589,KHDRBS3,GAD1,USP19,RND1,GLS,ADAMTS13,GRIK5,KCNN1,KCNQ3,ADAM22,N6AMT1,NEK1,NELL2,NF1,MTRF1L,RAD52,RGS10,RNASEL,SEMA6D,DOCK10,SYBU,FAM214B,RCOR3,MAPKBP1,KDM4B,TSNAXIP1,VAMP1,MTCL1,PSD3,DICER1,SPHK2,KCNAB1,PLSCR4,SENP7" Drug 6718_UP Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ADD2,KIDINS220,PLA2G6,AMH,APC,GAS7,ARHGDIG,ADGRB2,BMPR1B,CACNA1I,IL33,CRLF1,CACNA2D2,ADGRG1,ARMC8,CRY2,CTNND2,BRINP1,PARD6A,MTSS1L,FABP7,ZNF44,ERAP1,SIGLEC8,GPR75,STON1,SHISAL1,ITGA7,MOBP,ADAM22,MSR1,MYO7A,NCAM1,NEUROD1,NF1,PC,PDE2A,RGS12,PNMA8A,NEK11,ZFP2,ZNF821,ZFP30,SH3BP2,DZIP1,SLC9A5,IZUMO4,ARHGAP26,LMO3,COBL,TACR1,TAL1,SMG6,PCDHA5,TUBB1,VIPR2,REEP1,ZNF225,MVB12B" Drug 4252_UP Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "PKP4,APBB1,MARK4,ATP1A2,NOL4,KSR1,CACNA1I,LDB2,REPS2,CNTFR,AKAP6,IFFO1,NCOR2,CSF1R,ARHGEF10,MICAL2,PDE4DIP,CNTNAP2,CTNND2,RIPOR2,DAPK3,SV2B,EDNRA,EIF4G2,NCALD,ETV1,NRN1,FGFR1,SYT17,NEU3,SRCAP,PCDH17,GPR17,MCHR1,GRK4,GRIK5,ELOVL5,HTR5A,IRF8,NPTX1,MAPK8,MAPK10,CNNM2,PTAFR,C1orf54,RGS4,RGS12,SCN2A,PREX2,BTBD7,SP4,RAP1GAP2,PHF24,TK2,TMOD1,TNS1,LAT2,MVB12B,DPF3" Drug 3321_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "ACTN2,AMPD3,GAS7,MARK4,ADGRG1,SULT4A1,CNR1,PICK1,CNTN1,FAM149A,NCOR2,DCAF4,SPOCK2,CTIF,TRAPPC9,DUSP9,HIPK3,PLXNC1,FGFR1,FOXG1,SEPT9,GLS,GRM1,GRM7,VSIG4,KHK,KIT,MAOB,MOBP,ADAM22,P2RY13,NPR2,GRAMD1C,SAMD9,PTHLH,C1orf54,RGS12,KCTD17,SLC11A1,SNCA,KIF13A,WDTC1,ZSWIM8,ST5,AJAP1,ARC,SYN2,SYT5,KIAA1107,DMXL2,PCDHGA10,OBSL1,CRTC1,TNS1,AMACR,VIPR2,SPHK2,DNALI1,SLC17A7" Drug 7400_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-07 1.41E-02 9.59E-06 1.09E-04 59 196 "AP2A2,AMPD3,APC,PPFIA3,CDK13,MPDZ,MYRF,CFAP410,MAP7,KYAT1,CCNT1,ARHGEF2,REPS2,B4GALT6,BAG4,CREM,MICAL2,CNTNAP2,DZIP3,ARHGEF4,SGSM2,EDNRA,EN2,KIAA1109,TRAF3IP2,B4GALNT1,DISC1,COPS8,HTATSF1,POLL,KLF12,DIPK1A,JAK2,KIF2A,KPNA5,MAPT,PBX1,SERPINI1,PLCD1,NUDT11,SCN8A,SUPT20H,PEX26,SLC22A4,LIMCH1,ELOVL4,STX1A,KIAA1107,ARHGEF12,TIMP4,VLDLR,LMF1,NSD2,ZBTB14,SPHK2,UPF3A,NT5M,ACTR3B,AAAS" Drug CID000001221 "R,S)-AMPA" Stitch 2.93E-07 1.43E-02 9.74E-06 1.11E-04 19 36 "AMPH,CA4,NTM,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,TUB" Drug CID000002215 NSC755875 Stitch 2.95E-07 1.45E-02 9.81E-06 1.12E-04 52 165 "ABAT,ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,IGDCC4,CACNA1B,CACNA1E,CACNA2D1,CARS,CCK,CCKBR,CHRM1,CHRNA4,CHRNB2,CALY,DRD1,DTNA,EEF1A2,APH1A,DMTN,ZMYND10,PPP1R1B,GAD1,GAD2,SULT1C4,GFAP,LOXL3,GRIK1,GRIN2C,GRIN2D,HTR2A,HTR5A,KCNH2,MAOB,BCO1,NUCB1,OPRL1,PDYN,PENK,NLE1,GLDN,SOX10,APOM,VPS13A,MLST8,TRH,PORCN" Drug CID000004054 memantine Stitch 3.03E-07 1.49E-02 1.01E-05 1.15E-04 33 86 "ASIC2,ACHE,BCHE,CHRNA4,CHRNB2,BOC,DBN1,GRIN3A,RCAN1,STX2,GLRB,CNDP1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MMP16,OPA1,PTPA,SLC6A9,SLC17A7" Drug 2084_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.07E-07 1.51E-02 1.02E-05 1.16E-04 54 174 "ABAT,ABHD6,ADRB2,MTUS1,ARNTL,MARCH3,ALDH4A1,ST3GAL5,HIP1R,SPAG9,CHN2,NMT2,ABCG1,CTH,DNAJC6,PLPPR4,EFNA3,RGS17,CDKL3,TAOK3,TESK2,BAIAP2,FLNC,DPYSL4,PNMA2,FYN,KIF5C,LIFR,MMP16,PCDH9,PDGFRA,SERPINI1,RETREG1,PRPH,PTCH1,PTX3,RGS4,RPS6KA2,SH3GL3,SYBU,KDM4B,TNIK,ELOVL4,CEP68,RGL1,SYT11,SYT1,COBL,KIAA0930,PSD3,TGFBR3,SSBP2,DNAJC12,PLSCR4" Drug CID000121918 "L-689,560" Stitch 3.07E-07 1.51E-02 1.02E-05 1.16E-04 16 27 "GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,JMJD6" Drug CID000002071 "1-aminoindan-1,5-dicarboxylic acid" Stitch 3.13E-07 1.53E-02 1.04E-05 1.18E-04 18 33 "APAF1,KCNMB4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug 1929_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HG-U133A Broad Institute CMAP Down 3.17E-07 1.55E-02 1.05E-05 1.19E-04 58 192 "PKP4,CNTNAP1,APP,ARHGAP5,ASPH,STX16,ATP2B1,WASF1,SLC4A7,DZIP3,DDX46,RBM12,KCTD3,EFEMP1,KIAA1109,FHL1,SEC23B,PDLIM5,ATP2C1,OGA,STAG2,NCKAP1,GART,GLS,HTATSF1,OS9,NR3C1,HAS2,RBPJ,KCNMA1,KTN1,PAXBP1,MEF2C,NAP1L1,NUCB2,PCMT1,STRN3,PPM1B,VPS13C,C1orf109,RBBP6,WDR47,SON,GLT8D1,PEG10,CLASP2,EPB41L3,LARP4,DIP2A,TACC1,TCF4,TCF7L2,SIRT1,R3HDM1,UBE3A,DNAJC12,ZNF189,EVI5" Drug 3905_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.17E-07 1.55E-02 1.05E-05 1.19E-04 58 192 "DPF1,ASIC1,ABHD6,SLC12A5,PLA2G6,ALCAM,MARK4,ASPH,CFAP410,CAMK2B,RCBTB2,RAB33A,CNTN1,WHRN,ABCG1,PDE4DIP,KIAA0586,CELSR3,ANKMY1,ST3GAL6,OLFM1,AGAP2,ALDH1L1,GFER,GLYR1,POLL,GOLGB1,ADAMTS13,NR3C1,ITGA7,LMO1,MAPT,MOBP,ZNF862,NOS1,SERPINI1,SMIM7,CEP41,GRAMD1C,TMEM231,ENOX1,RPS6KA2,RPS20,KCNIP1,CLIP1,ZFP2,CPEB3,EPN2,ATP10B,TEX15,DICER1,CHST8,TRPC1,TRPM2,LMF1,WIPF1,XRCC4,HPS4" Drug 4144_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.17E-07 1.55E-02 1.05E-05 1.19E-04 58 192 "NDRG2,ADORA1,KIDINS220,APLP1,FAM131A,PPFIA3,ASPH,ALDH7A1,SYNJ1,CACNA1D,CBFA2T2,ARHGEF2,SEPT7,ASIC3,LHX2,TCEAL2,CSF1R,RIMS2,NOS1AP,GPRASP1,MAGI2,RCAN1,DYRK1A,EDNRA,HIPK3,ING4,VPS13B,FHL1,KHDRBS3,GAD2,SEPT9,RND1,GNG3,GPER1,ELOVL5,TJAP1,KCNF1,KCNMA1,KCNN1,SMAD1,KITLG,NF1,PLCD1,TCP11L1,FNDC3A,SLC9A5,WDTC1,DOK5,SS18,PLCB1,EXOC7,ZEB1,PARD3,CABIN1,TRPM2,UCHL1,EPM2A,SENP7" Drug 7489_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.17E-07 1.55E-02 1.05E-05 1.19E-04 58 192 "AP2A2,KIAA1324,LTBP4,APBB2,APOC1,ATP2A2,MTMR3,MTMR2,GYG2,SGCE,NEURL1,CRLF1,ADGRG1,TAOK2,RAB33A,STOML1,COL9A3,MYRIP,CRMP1,CSF1R,RGS6,CTH,EDRF1,DAPK3,HP1BP3,SPOCK3,DTNB,HIPK3,FEM1B,KIAA1109,FGFR1,FHL1,DCTN2,FYB1,GLYR1,GNAS,EML4,NR3C1,GRM1,HAS2,PTGDR2,VWA5A,MBP,KITLG,MMP17,PDE3B,PPP5C,FAM120C,PTX3,RGS3,EMID1,ZNF821,FNDC3A,BTBD7,INKA2,RGL1,PIK3R5,MVB12B" Drug CID000126757 GYKI 53655 Stitch 3.20E-07 1.57E-02 1.06E-05 1.20E-04 17 30 "STX2,CACNG2,GAD1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug CID000107831 AC1L32TU Stitch 3.20E-07 1.57E-02 1.06E-05 1.20E-04 17 30 "CALB1,AIFM1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,SST" Drug CID000104810 barium Stitch 3.22E-07 1.58E-02 1.06E-05 1.21E-04 48 148 "KCNH8,ADORA1,PHF12,ANXA7,CACNA1I,CACNA1G,WASF1,CACNA1A,CACNA1B,CACNA1E,CALM1,CHRM1,EPHB1,KCNMB4,ADAMTS13,KCNA1,KCNA6,KCNC1,KCNH1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN3,KCNQ3,MTR,NOS1,NPPA,P2RX7,KCNK10,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,CNNM2,SST,TRH,TRPC1,TRPC3" Drug CID000108001 "3,5-dihydroxyphenylglycine" Stitch 3.33E-07 1.63E-02 1.10E-05 1.25E-04 26 60 "ATP2A2,BSN,CA4,CARS,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNK3,LIMS1,MAP4,PDYN,MAPK3,SLC1A3,PLD4" Drug 4585_DN Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-07 1.69E-02 1.11E-05 1.27E-04 55 179 "ADD3,OSBPL8,CDC42BPA,ANK3,CDC14B,ATP2B1,SPAG9,CDC27,SLIT2,FEZ2,TBC1D5,NR1D2,EGFR,EIF4G1,EIF5,WAC,CAP2,PDLIM5,STAG2,SPIN1,HTATSF1,FERMT2,AGFG1,IL6ST,MAP4,MBNL1,MBP,MYO6,NEK1,SSH1,ING3,MED1,PKN2,PLEKHB2,SLC25A36,SEC14L1,SMARCA4,KDM4B,SON,MYCBP2,PEG10,TROVE2,PRRC2C,TBL1X,EHBP1,ZEB1,TRIM2,WASHC4,DICER1,KAT6B,UBTF,USP1,ZNF24,SNX27,FXR1" Drug 1800_UP Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "BRAP,KIDINS220,ALAD,LTBP4,PPFIA1,ATM,SLC4A4,CALB2,CNOT8,NIPBL,CHD1L,CPS1,ZFYVE16,GIT2,DBT,ARMCX2,EDNRA,FCF1,RBM12,ING4,IQCG,TRMO,DLL3,ERAP1,ARFIP1,GLS,PCLO,GRIN1,ATXN2L,KLF12,HMGCR,HNMT,MDFI,TAGLN3,NF1,NFYA,CNOT4,PAK3,RC3H2,PPP2R5C,SAMD9,PTPRE,RAD52,RGS10,TTLL7,NEK11,PEX26,CCDC88A,SLC20A2,FNBP1,ZHX3,SPTB,NXT2,ATP11A,TCF4,HIRA,NT5M,RNF170,AAAS" Drug 5051_UP Roxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ASPHD1,ASIC1,ADRA1D,AK2,OGT,APAF1,KCNAB2,ARHGDIG,MARK4,NOL4,NRP2,ASIC3,RAB26,PLCH2,PHF14,ARHGEF4,RIPOR2,RIMS3,CNIH3,DTNB,COQ7,MTSS1L,FGFR1,EFCAB2,GAB1,SYT17,GFER,GFRA1,PTGDR2,HPSE2,MAP2,MYT1,PCDH9,PDE4D,GPR85,PPARA,MAPK10,ZSCAN32,PID1,RASGRF1,IL17RB,SH3BP2,FRMPD1,DOCK10,HKDC1,CNKSR2,PKNOX2,SLC15A2,IZUMO4,SPP1,SPTB,MAPK8IP3,PHLDB1,VAMP1,TEX15,TMOD1,ZMYND8,RPRM,VGF" Drug 5098_UP Sulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "TTYH1,ASIC2,TRMT9B,CADM3,N4BP2L1,MYOM1,LDLRAD4,NEURL1,CDH10,CHGB,CHRNA4,CABP1,CSF1,RIMS2,MFAP3L,HS3ST2,TOM1,ST8SIA3,AASS,SRPK3,MTSS1L,FAM198B,ST3GAL6,SORBS1,GABRA2,TRAF3IP2,HBS1L,SEPT9,GNAO1,GRK4,ADAMTS8,PADI2,PTGDR2,HNMT,KIT,AFDN,MYO7A,NDUFA5,NF1,NNAT,NPR2,PDE4B,PACSIN1,POU6F1,KLHL11,FRMPD1,ASAP3,MAST1,SOX2,TSNAXIP1,MAPK8IP3,SEMA4A,PCDHGA1,PCDHA5,CRB1,VIPR2,ADAMTS9,KCNAB1,NUP214" Drug 202_UP raloxifene hydrochloride; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NDRG2,BRAP,AK2,ALAD,ALCAM,CDK10,ARHGAP5,ARNTL,CFAP410,SLIT2,LHX2,CNTN1,SLC4A7,NCOR1,DZIP3,PPP6R2,RIMS3,DAPK3,GIT2,DBT,BAIAP2,FGR,PCYOX1,TRMO,MALT1,NR3C1,PADI2,ITIH2,ADAM22,NF1,PAK3,PCMT1,CNNM2,LRRC49,ZSCAN32,RBBP6,REV3L,CCDC25,ZNF331,SEC14L1,SH3BGR,ITSN1,CHD9,ELMO2,SLC20A2,IFT122,TMCC1,WDTC1,GANAB,TRIM2,TEK,TRPC1,TSN,CADM1,WIPF1,SLC13A3,ZNF142,ZFAND5,MAP3K12" Drug 256_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ABHD6,BRAP,ADRA1D,AMPH,OGT,ANK1,APAF1,APP,ATP1A2,BCL7A,MTMR3,CACNA1I,CFAP410,CD38,CHGA,LHX2,HOMER3,CNR1,PCYT1B,IFFO1,MICAL2,ECE2,DCAF8,HP1BP3,EXOG,DRP2,EDNRA,TNK2,ENO2,CDKL3,ANKMY1,SMC2,CAMKK2,SEPT9,GLS,LILRA2,RNFT2,ATXN2L,KLF12,IRF8,ITPKB,STMN1,MID1,GIT1,MAPK8,PYGM,RGR,RGS4,FOXRED2,SLC1A7,FAM214B,ELMO2,CXXC4,CDK5RAP2,IFT122,KAZN,EXOC7,SPHK2,NUP214" Drug 2514_DN Ungerine nitrate; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "AP2A2,PLA2G6,AMT,APBB2,NFS1,KRIT1,CD86,AP4M1,PLAA,ENTPD4,VCAN,RUBCN,CTIF,SV2A,DTNA,ABI2,TUBD1,MTSS1L,ZNF589,GAA,SLC2A6,TJAP1,ARHGAP12,MAP4,ZNF862,MYT1,CNOT4,NUMA1,GPSM2,PLCB2,RC3H2,LRP12,MINDY2,RALGDS,ZCWPW1,GSTCD,ZNF671,MRAS,FBXO11,SLC15A2,BTBD7,SLC20A2,ZHX3,EMC1,KIF1B,ZBTB43,SS18,CEP68,ARHGEF9,EXOC7,CAMSAP2,TCF7L2,SZT2,TPD52,SMUG1,LMF1,XRCC4,NT5M,ST7" Drug 5244_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "BIN1,AMT,ANK2,ATM,SLC2A11,ARHGEF2,CLGN,CACNA2D2,CLTB,SDC3,SPOCK2,MAGI2,KLHL3,TMCC2,E2F5,PLXNC1,EPHB1,PTK2B,DLC1,POLL,GNAO1,PRUNE2,GRB10,GRIK1,IRAK3,KCNN1,KCNN2,KIT,LSS,MOBP,NPY,NTRK2,PCDH9,SERPINI1,PLCD1,EPN1,LRP12,ZSCAN32,KHDRBS2,PNMA8A,KCNIP1,SH3BP2,FAM214B,DOK5,IZUMO4,SYT11,SYT5,ATP11A,TBL1X,TK2,TMOD1,RUNDC3B,UBE2H,FLRT2,VLDLR,NT5M,EVI5,PLSCR4,PARP11" Drug 4012_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "TTYH1,NDRG2,ADD2,RASL11B,SLC4A4,B3GALT2,ADAM23,NRP2,SCAPER,CACNA1G,CDC42,PLEKHB1,NRXN3,CSF1,LRIG1,ATRNL1,CNTNAP2,EXOG,EDN3,ETV1,FAM198B,PRELID3A,FYB1,GAB1,GNG4,GRIK5,GRM2,RASSF8,HTR5A,KCNC1,KCND3,KCNH1,KCNN1,MMP16,P2RY1,PALM,PDE2A,LRRN3,PRPH,GAL3ST4,RFX2,RGS12,RNASE1,NEK11,SYNDIG1,SCN2B,MRAS,SH3BP2,ST8SIA1,SLA,ATP10B,TROVE2,TACR1,KAZN,TAL1,TRPC1,TRPC3,TUBB1,BEST1" Drug 4796_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "BRINP2,ATP6V0A1,CFLAR,SGCE,CACNA1G,BTRC,CFAP410,KALRN,SCARB1,ADGRG1,RCBTB2,FOXN3,PLEKHB1,RAB28,CTH,RIMS2,PHYHIP,GIT2,DSCAM,FOXG1,ALDH1L1,RAB40B,GPER1,GRB10,GRIK5,GRM8,PTGDR2,TJAP1,KCNN1,MBNL1,ADAM22,NF1,OMG,P2RY1,PLCD1,LRRN3,RALGDS,C1orf54,GSTCD,FBXW7,SATB1,HSPA4L,SH3BP2,SLA,SLC1A7,FAIM2,NXT2,PHLDB1,EXOC7,WSCD1,TCF7L2,TRIM2,DOCK9,ARHGEF12,DAAM2,ZBTB14,SLC30A3,SLC17A7,RNF146" Drug 2252_UP Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ADGRF5,APC,CDK10,MARK4,CBFA2T2,SCARB1,CHM,TPP1,HOMER3,RCHY1,CSF1R,CTIF,DYRK1A,MBNL2,ING4,EPB41,MTSS1L,EPHB1,EFS,REEP2,FGF1,FGFR3,NSG1,OGA,GLS,GRM8,ATXN2L,TJAP1,KPNA5,MID1,OMG,PALM,PDE1C,GPR85,PACSIN1,SAMD9,RGS12,TCP11L1,ASAP3,DOCK10,FNDC3A,ZNF334,HECW1,SPTB,THSD1,PHLDB1,ABCC8,ARHGEF9,EXOC7,TCF4,OBSL1,TMOD1,RIMBP2,TRPC1,FLRT2,CLDND1,ZNF45,SCG2,PHTF2" Drug 6988_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NDRG2,KIDINS220,PLA2G6,AMPD3,AMT,CFLAR,SCAPER,BAIAP3,TAOK2,EPS15L1,QKI,RIMS3,DBN1,MED12,EFNA3,ENO2,FHL1,DPYSL4,OGA,GAD1,INPP5K,AHDC1,RAB30,GLS,GNG3,GPM6B,ADAMTS13,GRM1,HNMT,IL6R,INPP5B,KCNN1,MDFI,TAGLN3,NEK1,NOS1,NTRK3,PDE3B,PLEC,MAPK10,RGS12,CARF,FBXW7,PAQR6,RXRA,MRAS,SYBU,NLGN1,DOK5,EMC1,UNC5B,ZNF423,TACC1,TEX15,SLC44A1,ZBTB14,SYNC,SLC30A3,NUP214" Drug 2082_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ASIC1,ADD1,AMPD3,AMT,APP,CDC14B,CDK10,NUMB,KYAT1,CCNT1,CNOT8,BAG4,CHD1L,SH2B1,HINFP,VCAN,PDE4DIP,SDC3,ARHGAP32,DBT,SIDT2,SCML2,BAIAP2,TRAF3IP2,ERAP1,DISC1,INPP5K,TXNL4A,COPS8,DIDO1,KIF3A,ICA1,INPP5B,JAK2,LIG4,MAP4,MBNL1,PIK3R1,NLE1,SLC25A23,FA2H,SYTL2,ZSCAN32,SH3BGR,SH3BP2,ASAP3,BTBD7,SPATA7,ARHGAP26,JMJD6,VAMP1,TRIM2,TNS2,ZMAT3,TSN,XRCC4,WNK1,MAP3K12,EPM2A" Drug 7472_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ABHD6,ALCAM,AMH,BIN1,ALDH4A1,CFLAR,KSR1,SYNJ2,CACNA2D1,CALB2,FOXN3,LHX2,CNTFR,TBC1D5,SPOCK2,CTIF,JAKMIP2,DMPK,SLC12A6,SORBS3,ELAVL2,EN2,PIPOX,TBC1D16,FHL1,OGA,GAD2,C1QL1,RAB30,GLS,GRM2,RNFT2,RASSF8,INPP5B,ITPKB,MIA2,NNAT,NOS1,PLCD1,PLXNB1,PPP2R2B,PPP5C,PTN,RAB3A,ZDHHC14,MYH14,TCP11L1,RPS20,ASAP3,SMARCD3,SNCA,DOK5,INKA2,STXBP1,COBL,KAT6B,ZNF189,MAP3K12,MARCH8" Drug 6747_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "DPF1,KIDINS220,NLGN4X,ALK,PPFIA2,FAM131A,ATP2B3,N4BP2L1,BMP7,GYG2,CFAP410,CACNA1A,CACNA1D,CACNA2D1,CD86,RAB33A,DNAJB5,SULT4A1,CNTFR,SLC4A8,ARHGAP24,RABGAP1L,ST8SIA3,EDNRB,ELAVL3,NRN1,AGAP2,ATP8A2,ALDH1L1,GRIK1,ELOVL5,DIPK1A,KCND3,MARK1,MDFI,KITLG,ADAM22,TAGLN3,NF1,NPR2,NTRK2,P2RY1,PAH,PDE4B,GPR85,PIK3CD,RETREG1,PTH1R,RYR1,SELL,ZFP30,HKDC1,PREX2,TROVE2,SYP,TEX15,TK2,RUNDC3B,CADM1" Drug 6683_UP Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ADCY6,PPFIA4,BCAS1,CDK13,ASTN1,ATP2B2,SLC2A11,NRP2,BMP7,SCAPER,CALB2,DGKI,CRLF1,CBARP,CHI3L2,B4GALT6,ZFYVE9,CLCN4,QKI,CRY2,SUSD5,CTNND2,NTM,ATN1,EDNRA,EFNA3,ENO2,EPB41,DLC1,ST3GAL6,EFCAB2,GLYR1,GPR75,GPR19,STMN2,GRM8,AP4S1,AFDN,NF1,NNAT,PFKFB4,LRRN3,ELOVL2,ZSCAN32,KCTD17,ITSN1,FRMPD1,SLC6A9,SLN,EMC1,ARC,TLR4,SEZ6L,TRPC3,ZNF24,SPHK2,WNK1,SCG2,GAN" Drug 6369_DN CGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ACTN2,MRTFA,TRMT9B,BMPR1B,SYNJ1,FUBP1,CACNA1I,CACNG1,HAP1,QKI,CNR1,IQCK,SH2B1,PDE4DIP,RIPOR2,DCAF8,MFAP3L,SMG7,RABGAP1L,CDON,EDIL3,EGFR,MBNL2,DCTN2,FYB1,GPD2,LILRA2,GPR17,GPER1,GRM7,PTGDR2,HSF2,KCNA2,LIG4,LSS,MAOB,MATK,ADAM22,OPCML,OPRL1,SNTG1,PALM,PMP2,PACSIN1,RGS4,STUM,FNDC3A,RIMS1,RBM34,SCN3B,WDTC1,DOK5,ZSWIM8,SPTB,MAPK8IP3,SYN2,PIK3R5,TRO,UBE3A" Drug 5703_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ASIC1,NDRG2,C1QTNF1,LTBP4,SYT13,SLC4A4,ADGRB1,CACNG1,SLC16A4,CHRNA4,FHL5,WHRN,CREB5,GIT2,MAGI2,TRAPPC9,CDON,ATN1,DTNA,EDNRA,HIPK3,APC2,NRN1,FHL1,GPR153,GABRA2,SIGLEC8,GNG3,GNG4,PRUNE2,GPR22,PCLO,GRB10,RAPGEF1,GSN,ATXN2L,HTR2A,INPP5B,KCNH2,MBD1,OPCML,MINDY2,MAPK8,ENOX1,ZNF493,TCP11L1,ZNF821,RASA3,PREX2,SLC2A5,PKNOX2,SPTB,NPAS3,TACC1,PCDHGB6,PCDHA5,SEMA3B,PAK5,CAMK1G" Drug 3065_DN Primidone [125-33-7]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NR0B1,C1QTNF1,ANK2,FAM131A,LGR5,ATP2B2,CA12,CACNB4,HIP1R,NEURL1,CDH8,LARGE1,EPS15L1,CLCN4,NCOR2,MICAL2,PDE4DIP,RUBCN,DGKG,COQ7,F5,DLC1,FER,ALDH1L1,GPD2,STMN2,GRM1,KCND3,KCNK1,LIG4,MID1,AFDN,MMP16,TAGLN3,NEFM,NNAT,NOS1,CNOT4,NTRK2,OMG,PDE4D,PILRA,PPP2R2B,SCG5,SLC1A7,LIMS2,SMARCD3,KDM4B,TNIK,ZSWIM8,RAP1GAP2,SPART,SYN2,TAL1,TCF7,TMOD1,TRIO,SPHK2,PRDM2" Drug 3793_UP Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ACTN2,ADD2,LTBP4,TRMT9B,APAF1,LGR5,CDC14B,ASCL1,PDE8B,ATP6V0A1,KSR1,CACNA1I,CDK5R2,ZFYVE9,RAB26,ARHGEF4,NOS1AP,DMPK,TRAPPC9,DSCAM,DTNA,SGK2,HEYL,TNK2,RASGRP2,EZH1,GALC,GLI2,TOX3,PRUNE2,GRK4,GRIK5,GRM1,KCNF1,KCNJ5,LMO1,ADAM11,OLR1,SNTG1,CDK18,PDE4D,PFKFB2,SPATA6,C19orf57,DCHS2,PTAFR,PTPRZ1,ZMAT4,KLHL11,SLC2A5,PKNOX2,SOX2,HECW1,MAPK8IP3,TPM1,CA14,SPHK2,SLC30A4,SLC17A7" Drug 5919_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "MRTFA,ATP1A2,N4BP2L1,KIF1A,NRP2,CAMK2G,CDH10,LARGE1,EPS15L1,STOML1,TCEAL2,PDE4DIP,PHF14,GIT2,DTNB,TOM1,SGK2,NCALD,EZH1,KAT8,ZNF589,AFF2,SORBS1,GNAS,DIDO1,SYNPO,KCNB1,KCNQ3,MAP2,ADAM22,NF1,NFYA,OXTR,CDK18,PDE4B,PDE4D,POU3F4,CNNM2,PTHLH,ZSCAN2,ARHGEF10L,TMEM206,HSPA4L,SLC15A2,SNCA,RBM34,PDZD2,FNBP1,HECW1,TSPYL2,BHLHB9,TRIO,RUNDC3B,ZMYND8,CADM1,FLRT2,PRDM2,PARP6,GAN" Drug 5823_UP Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ABAT,MTUS1,C1QTNF1,APC,SEMA4G,ATP2B2,KIF1A,CFLAR,CFAP410,NRXN3,CLU,CHD5,USP6NL,GIT2,CNIH3,MFAP3L,KIAA0753,RABGAP1L,OPTN,TUBD1,LRRC23,LRRC17,ZNF589,C1orf61,TRMO,DISC1,GART,GNAS,GPM6B,KIF5C,MAPT,MMP17,ADAM22,TAGLN3,NOVA2,NPTX1,PACSIN1,PPP2R2B,CNNM2,BCAS3,CNTLN,TMEM231,RASGRF1,ZMAT4,RGS10,FNDC3A,ANKRD6,RPH3A,KDM4D,SLC20A2,SLCO1A2,TMCC1,MCF2L,WWC1,CRTC1,TEX15,CABIN1,VAV2,SCG2" Drug 2291_DN Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "RALGAPA1,NDRG3,NME5,BEGAIN,BIN1,APC,FAM131A,AQP4,CFLAR,SYNJ1,SYNJ2,CFAP410,CLGN,CRLF1,SLIT2,AKAP7,GREB1,JAKMIP2,HP1BP3,IQCG,GALC,SEPT9,GLYR1,GPD2,TDRKH,SPACA9,INPP5B,ADAM22,NF1,NPR2,SLC11A2,SLC25A23,MAPK8,FAM120C,PEX5,RAB3IL1,SBF1,SH3BP2,SMARCA4,SNCA,ZBTB43,INKA2,ELOVL4,VAMP1,KIAA1107,PSD3,TMOD1,TMPO,ZMYND8,ZKSCAN5,MICAL1,ZNF24,SPHK2,SLC30A3,WNK1,DNALI1,EPM2A,PHTF2,SENP7" Drug 6389_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "TKTL1,ADD2,ADORA2A,LTBP4,BEGAIN,TRMT9B,GAS7,BCAS1,ARNTL,ARRB1,ASCL1,ATP6V0A1,KIF1A,BMP7,SCAPER,CACNA2D1,HAP1,RUNX1T1,ADGRG1,FOXN3,NRXN3,PLAA,CRMP1,ABCG1,CSF1,DMPK,EGFR,PRELID3A,ALDH1L1,SRCAP,ADAM28,RND1,TDRKH,PGAM2,MAPK8,VPS13C,WDR25,PTPRD,RAB3IL1,RGS10,CSRNP3,ASAP3,NTNG1,SLA,PREX2,PKNOX2,TSNAXIP1,SOX10,ZHX3,SPTAN1,IQSEC2,DDN,NCDN,NR2E1,PIK3R5,SEZ6L,TPM1,RPRM,KCNAB1" Drug 6137_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "BIN1,APAF1,APBB2,ASPH,SYNJ2,MAP7,CHRNB2,DCC,SV2B,ATN1,DSCAM,DTNA,E2F5,EDN3,HIPK3,HEYL,SIDT2,EFNA3,CELSR3,MBNL2,EGR3,SORBS3,ELAVL3,LRRC23,RASGRP2,ERBB2,ETV1,FGFR1,AGAP2,IQCG,FLT1,CAMKK2,B3GAT1,ZMYND11,GFER,PRUNE2,KCND3,MYT1,MAPK8,PROX1,BCAS3,ACSS3,KHDRBS2,CRTAC1,RGS12,SH3BGR,ASAP3,EPN2,ARHGAP26,TBCEL,WSCD1,ZEB1,TRIM2,DOCK9,PCDHA5,TPM3,AMACR,MKRN3,KCNAB1" Drug 4150_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "APAF1,APBA2,AQP6,SLC2A11,CFLAR,CNN3,WHRN,AATK,ARHGEF10,EDRF1,DAPK1,DCT,EDN1,ELAVL3,SRPK3,ERBB2,TUBB4A,FGFR3,FHL1,DCTN2,FAM49B,NSG1,OGA,FYB1,FYN,CPLX2,ALDH1L1,POLL,GPR22,PCLO,SPACA9,KLF12,SCRG1,KCNN1,KHK,KIF5A,MEF2C,MID1,NDUFA5,NTRK2,NUMA1,PDE1C,ELOVL2,RAB3A,PID1,RGS12,GSTCD,EMID1,SLC1A3,KDM4B,CDK19,THSD1,MAPK8IP3,SZT2,SLC35G2,WNK1,SLC17A7,PARP11,NUP214" Drug 3006_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "SYN3,SPARCL1,AMPH,FGF17,CACNG1,HIP1R,MAP7,USP2,INA,NEURL1,DGKI,ARHGAP33,CHGB,WHRN,NRG2,CRYBB1,CSF1,SIPA1L1,SV2B,ABCC9,EDN3,SRPK3,STX2,CACNG2,CORO2B,GAD2,HPGDS,GPR19,GPR22,SPACA9,GRM2,ATXN2L,KLF12,SYNPO,HPCA,SCIN,KCNF1,KIF5A,SCAMP5,NEFM,NELL2,DCHS2,SYTL2,ELOVL2,NUDT11,NEK11,KCNIP2,SOX10,TAC3,TACR1,AP4E1,R3HDM1,SEZ6L,LILRA4,TPM3,TRIO,FLRT2,SLC17A7,HRASLS" Drug 5835_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "APBB2,APOC1,SEMA4G,CDK13,ALDH4A1,CFLAR,B4GALT6,CNOT8,ARMC8,CREB5,AKAP12,NCOR1,PLCH2,GIT2,DBT,ARMCX2,SMG7,SGSM2,ABI2,MRNIP,STX2,ANKMY1,SYT17,INPP5K,GLI2,DIDO1,GRIK5,IL6R,JAK2,KCNMA1,LAMA2,MAPT,MKLN1,TAGLN3,NF1,PID1,RBBP6,MORC4,RGS10,MYH14,TCP11L1,ZNF415,TMCC1,TNIK,EMC1,TROVE2,SAMSN1,TACC1,IQCE,TRIM2,PHF24,TPD52,HIRA,WIPF1,EMSY,CIAPIN1,NAV2,NUP214,RNF146" Drug 4223_DN Nystatine [1400-61-9]; Down 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "MTUS1,PLA2G6,SEMA7A,APOC1,BCL2L2,CFAP410,CACNB2,REPS2,CDC42,ENTPD4,SLITRK5,PHF14,CTIF,MFAP3L,DYNC1I1,DTNA,TOM1,FCF1,PLXNC1,EPHA5,ZNF391,CDKL3,ETV1,RRAGB,FGF1,TRMO,ZNF44,GAD1,GUCY1A2,HNMT,SHISAL1,PACRG,MATN3,TM6SF1,CNOT4,CLDN11,PAK3,PIK3R1,CNTLN,PTCH1,RGS10,MYH14,SELL,ZNF821,FBXO11,SLC1A7,SLC20A2,LIMCH1,KDM4C,ARHGAP26,CDK19,SAMSN1,ARHGEF12,VGF,WIPF1,NSD2,XRCC4,ZNF225,PLSCR4" Drug 3334_UP Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NDRG2,ADRA1B,NME5,C1QTNF1,LTBP4,CADM3,ADAM23,CAMK2B,ARHGEF2,CHI3L2,TAOK2,LHX2,NCOR2,CSF1R,NOS1AP,RIMS3,DAPK1,CTIF,DMPK,CNNM1,EGR3,ERCC2,ZNF589,CAMSAP1,SCARA3,FOXG1,DCTN2,IQGAP2,TMEM8B,PCDH17,RND1,HPGDS,GNAS,PRUNE2,ADAMTS13,GRM1,ICA1,KCNMA1,KIF5A,LAMA2,MMP17,CD200,PDE4B,LRP12,RAB3IL1,ASAP3,SLC1A2,SLC11A1,BTBD7,SOX3,TNIK,HECW1,ARHGAP26,ATP10B,ST5,TCF4,TRO,FAM155A,PLSCR4" Drug 3939_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "DPF1,GRAMD1B,BEGAIN,APLP1,ADGRB2,CACNA1I,CFAP410,CAMK2B,CCKBR,STOML1,WHRN,CABP1,NCOR2,RIPOR2,DGKG,DAPK1,SRGAP3,DYRK1A,PLXNC1,ELAVL3,ERCC2,OLFM1,FGFR1,DCTN2,NSG1,GAP43,C1QL1,RND1,GNAO1,GPM6B,PTGDR2,KLF12,ICA1,ITGAM,KCNH2,L1CAM,MARK1,MYCN,NPR2,NTRK3,PENK,DIRAS2,PTAFR,RAB3A,PNMA8A,SYNDIG1,STUM,ASAP3,SPP1,SSTR2,ABCC8,VAMP1,TAC3,ATP11A,SYNE1,TEK,TMOD1,PIK3R5,SLC30A3" Drug 1749_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ADORA1,AMPD3,CNTNAP1,ASCL1,PDE8B,ADGRB2,CACNA1A,CALB2,CACNA2D2,CHN2,CNTFR,IQCK,CRYM,DCT,TMCC2,TRAPPC9,DPH1,ATN1,CNNM1,EFNB3,SORBS3,TNK2,ELN,FCGRT,FLT1,GAP43,ALDH1L1,GNAO1,GRIN1,CACFD1,KCNF1,LAMA2,MBP,GIT1,SAMD14,MYT1,DUSP26,PACSIN1,PPARA,PTN,RNASE1,PAQR6,RXRA,ATXN2,BCAN,LIMS2,SLC6A11,WDTC1,SPTB,SS18,PLCB1,SYN2,CRTC1,DNAH7,LILRA4,VGF,NPDC1,CAMK1G,NUP214" Drug 4063_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NR0B1,ARHGDIG,CDK13,CADM3,ADGRB2,ADGRB3,FUBP1,KALRN,CAMK2B,RUNX1T1,TMEM257,TAOK2,COL9A3,IFFO1,RIMS2,SEC14L5,C2CD2L,EBI3,ING4,EPHB1,IGSF6,GAP43,SIGLEC8,GNAO1,PRUNE2,ATF7,TPPP,HNMT,HSD17B1,KCND3,LAMA2,LSS,MAN2A2,AFDN,OGG1,PDGFRA,PLCD1,MAPK8,PTAFR,PTPRN2,ACSS3,CCDC40,KCTD17,ASIC4,SLA,RPH3A,SNAP25,SOX10,SPTB,MAPK8IP3,PLCB1,SYT5,SMG6,HIF3A,DAAM2,VAV2,SLC30A3,KCNAB1,NUP214" Drug 3410_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ABHD6,SLC12A5,PLA2G6,LTBP4,AMPD3,BIN1,APBB2,APC,SEMA4G,CFLAR,CAMK2G,CDC42,SOCS6,TPP1,FAM189A2,CSF1,MICAL2,SDC3,DCAF8,DAPK3,C2CD2L,KIAA1109,SEMA4D,DPYSL4,GLS,GRIK5,NR3C1,RASSF8,KCNF1,KCNQ3,NDUFA5,NRGN,OXTR,PLEC,MTRF1L,PLPPR1,ZSCAN32,RAB3A,C1orf54,RGS12,TCP11L1,PREX2,EPN2,SHANK2,SLC22A4,ZKSCAN3,ZNF423,PHLDB1,PLCB1,EXOC7,KIAA1107,SZT2,PCDHGA10,ARHGEF12,TK2,TRPC1,VGF,KCNK12,PRDM2" Drug 5993_DN Proxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "APOC1,PDE8B,ATP6V0A1,CFLAR,CBFA2T2,TAOK2,PLAA,FADS2,AKAP7,SH2B1,CNTNAP2,GIT2,MFAP3L,RABGAP1L,CDON,DRD1,TOM1,EFNA3,SORBS3,MRNIP,SCML2,ZNF589,FGFR1,MALT1,COPS8,TDRKH,GRB10,IL6R,IL6ST,KCNF1,MIA2,ZNF862,NF1,NUMA1,PRKAR1B,PRODH,CNNM2,RIPOR1,RAD51D,ATG16L1,ARHGEF10L,ROBO1,NEK11,PAQR6,FBXO11,SMTN,SNCA,IQSEC2,PLCB1,TRIM2,TNS2,TPD52,VAV2,VLDLR,LMF1,XRCC4,MAP3K12,GDPD5,MVB12B" Drug 3467_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "AK2,GAS7,PLA2G4C,ATP2A2,CFLAR,LDLRAD4,CAMK2G,CBFA2T2,ARHGEF2,CLU,SLC4A7,SLC4A8,CRMP1,GREB1,DCAF8,EFNA3,ELAVL3,ERBB2,FHL1,FOXG1,CAMKK2,OGA,ZNF44,GAD1,PCSK1N,GRB10,HSD17B1,IL6R,IL6ST,KCNH2,MAOB,MGAT3,KITLG,MMP16,CD200,ADAM22,ZNF862,STRN3,LRP12,TNPO2,PRODH,PTHLH,RAB3IL1,GTDC1,SLC25A36,RYR1,SBF1,FAM214B,BTBD7,SPTAN1,DIP2A,PLCB1,KAZN,EHBP1,ARHGEF12,TRIO,REEP1,WNK1,GDPD5" Drug 4093_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "NR0B1,APC,AQP4,ATP1A2,SLC4A4,CADM3,SCAPER,CACNA1G,BSN,CACNA2D1,CAMK2B,MTMR7,TMEM257,DGKI,NRXN3,VAX2,PICK1,CHD5,SEC14L5,KIAA0319,NTM,TRAPPC9,DTNA,DYRK1A,EDIL3,ST8SIA3,ING4,RASGRP2,EFS,ARMCX1,LYVE1,GNAL,GNAO1,GRIK3,ELOVL5,HPSE2,HTR5A,KCND3,KCNJ4,VWA5A,PACRG,ADAM22,PRKAR1B,PROX1,RFX2,MYH14,SEMA6D,SCN2B,ASAP3,SLA,PKNOX2,SOX2,SOX10,ARHGAP26,SSTR1,COBL,TAL1,TRO,RPRM" Drug 2350_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "C3orf14,NDRG3,PLA2G6,PLA2G4C,MARK4,BACH1,BMP7,CACNA1A,CD86,CDH2,ZFYVE9,CLCN4,CPS1,VCAN,SLITRK5,DZIP3,ARHGAP32,DGKG,DBT,ST8SIA3,CNNM1,ABI2,PLXNC1,MRNIP,VPS13B,RASGRP2,NCALD,ZNF589,PRKAG2,PDLIM5,HBS1L,ERAP1,DISC1,INPP5K,GJB1,LILRA2,GRB10,GRIK5,HNMT,KCNN1,GIT1,NF1,NOS1,NPR2,BCAS3,PTCH1,PTPN13,TMEM231,MRAS,SH3BGR,SH3BP2,DZIP1,SLC1A7,SLN,SNCA,ATP10B,TCF7L2,SSBP2,KCNAB1" Drug 7286_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "APC,SLC4A4,ATP6V0A1,SCAPER,BAIAP3,PLEKHB1,B4GALT6,NRXN3,CLCN4,STOML1,DNAJB5,QKI,HOMER3,PCYT1B,HAPLN1,ABCG1,DZIP3,EDRF1,RIPOR2,DTNA,EDNRA,EIF4G2,DENND4A,ETV1,VPS26C,RRAGB,KIAA1109,IQCG,FYB1,GAB1,DENND2A,GART,GNG4,GRM8,HLF,TJAP1,LIG4,MIA2,NDP,NPTX1,NLE1,MAPK7,CNNM2,BCAS3,TMEM231,RAD52,SH3BP2,PEX26,SLC6A8,TNIK,UNC5B,NXT2,ASTN2,CABIN1,TRO,CADM1,UGT8,VIPR2,KCNK12" Drug 5528_UP Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "AMT,CDC42BPA,APBA2,APC,CDC14B,SEMA4G,PDE8B,ALDH7A1,CADM3,CACNA1I,CFAP410,CACNA1A,SEPT7,CNTFR,WHRN,CSF1R,VCAN,EDRF1,DGKG,SGK2,FOXG1,GABRG2,TMEM8B,GPR162,RUNDC3A,POLL,GRIK5,GUCY1A2,KCNJ5,KCNN1,LAMA2,MAN2A2,MYL3,NOVA1,NTRK3,PDE3B,GPR85,PPP2R2B,MAPK10,SNRK,ELOVL2,TCP11L1,CNKSR2,PKNOX2,SLC20A2,SLN,KIF13A,ATP10B,ST5,CEP68,MLC1,TACR1,ROBO3,MCF2L,CUX2,SZT2,CRTC1,SLC35G2,TK2" Drug 5463_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "AGT,PLA2G6,BIN1,CDC42BPA,CDC14B,MARK4,ASTN1,DDX3Y,BAIAP3,HAP1,ARHGAP33,CHRNA4,FAM149A,WHRN,COL9A3,CSF1R,MBNL2,LRRC17,MTSS1L,FGF13,BAIAP2,FOXG1,AGAP2,TBR1,DKK3,SRCAP,PTPRT,DHX35,INPP5B,KCNA1,KCNMA1,LAMA2,MID1,GIT1,ADAM22,MYH7,MYO7A,NPTX1,MTRF1L,PPARA,FAM120C,RGS4,ZFHX4,ZNF821,FRMPD1,NLGN1,SLC6A8,ELMO2,SOX2,ZCCHC24,DOCK9,TF,AP4E1,LILRA4,PRMT8,WIPF1,NT5M,GDPD5,NUP214" Drug 5685_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ASIC1,ADCY2,ADORA1,PLA2G6,ADGRF5,LTBP4,SYT13,MRTFA,CDC42BPA,ASCL1,DNAH17,ATP2B3,AZGP1,FGF17,CACNA2D2,CRMP1,CSF1,ARHGEF4,RIMS2,HDAC9,SPOCK3,RASL10A,DISC1,GPM6B,AP4S1,SOX21,KLF12,INPP5B,KCNMA1,LAMA2,MN1,MOBP,MYL3,NECAB2,PRKCB,MAPK7,PBRM1,MYH14,PNMA8A,TCP11L1,LRRTM4,SLC30A10,ZNF821,PPP1R9A,PREX2,SLC2A5,KANSL3,SLC9A5,PDZD2,ATP10B,SYN2,EXOC7,TCF4,PCDHGB6,SZT2,PCDHGA10,DOCK9,PIK3R5,EPM2A" Drug 3315_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ADORA3,BEGAIN,CDC42BPA,CNTNAP1,FAM131A,ATM,CFLAR,CACNA1I,BAIAP3,ARHGAP33,FOXN3,TPP1,WHRN,ENTPD4,CSF1R,CNTNAP2,GREB1,ARHGEF4,DRD1,EIF4G2,DMTN,BAIAP2,SEPT9,POLL,NR3C1,RASSF8,IL6ST,KHK,VWA5A,MAP4,MMP17,ADAM22,NDUFA5,NPR2,NUMA1,CLDN11,PLCD1,TNPO2,MINDY2,PRKACB,ZSCAN2,TMEM231,KCNIP1,ITSN1,ASAP3,KDM4D,SLC9A5,PHLDB1,VAMP1,ARC,KIAA1107,FLRT2,WIPF1,SLC13A3,KCNK12,MKRN3,DNALI1,KCNAB1,NUP214" Drug 6344_UP Betazole hydrochloride; Up 200; 27uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "C1QTNF1,MRTFA,MADD,DNAH17,ATP6V0A1,KIF1A,CFLAR,ST3GAL5,MAP7,CBS,ENTPD4,CNTNAP2,ARHGAP24,SV2A,EDIL3,SIDT2,PLEKHO1,STX2,ANKMY1,ZNF589,TRMO,FYB1,DENND2A,C1QL1,ZNF276,GLYR1,MSL3,GPR17,GRM1,SCIN,INPP5B,MOBP,NF1,NOS1,CNOT4,PALM,RETREG1,PROX1,GON4L,ZCWPW1,NEK11,CNKSR2,SLC1A7,ZNF334,KDM4C,LHPP,ATP10B,SSTR2,TAL1,KIAA1107,PSD3,TK2,TUBB1,RPRM,REEP1,PARP6,SLC17A7,MVB12B,KAT6A" Drug 4993_UP Estrone [53-16-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ADRA1D,KIDINS220,BEGAIN,APAF1,N4BP2L1,AZGP1,SCAPER,CFAP410,CALB2,CCK,FOXN3,SULT4A1,CNTFR,FAM149A,NRG2,DCT,DNAH9,EGR3,ING4,HSD17B14,ZNF549,CDHR1,NRN1,FUT9,GABRA2,PCDH17,RUNDC3A,GRK4,GRIK5,ATXN2L,KLF12,ICA1,KCND3,KIF5C,MID1,AFF1,MYCN,NPPA,OPRL1,PLEC,ELOVL2,ZNF493,PNMA8A,ZNF334,SLCO1A2,NFASC,ACSBG1,PLCB1,TBCEL,WSCD1,SZT2,ARHGEF12,TK2,TNS1,LILRA4,REEP1,NT5M,SEMA3B,KCNAB1" Drug 7052_UP 0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ABHD6,AK2,MRTFA,APC,APP,GYG2,HAP1,CAMK2G,MAGI1,CHRNB2,WHRN,NOS1AP,ZNF804A,HS3ST2,EFNB3,KAT8,IQCG,GPR153,OGA,B4GALNT1,AHDC1,GPER1,NR3C1,NXPH3,ELOVL5,MAP4,MPP2,MYO7A,MYO9A,SLC11A2,NTRK2,SERPINI1,PLCD1,SLC25A23,PLXNB1,ZCWPW1,SEC61A2,DCUN1D2,PAQR6,SBF1,CCDC92,PEX26,SHANK2,KIF13A,KDM4B,ZSWIM8,NCDN,MAPK8IP3,JMJD6,VAMP1,VPS13A,WSCD1,CRTC1,CABIN1,TRH,ZMYND8,XRCC4,PRDM2,SEMA3B" Drug 4075_UP Metrizamide [31112-62-6]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ACTN2,AGT,AMPH,ANK1,ANK2,GAS7,ARHGDIG,ZSCAN18,BACH1,ADGRB2,RGS11,CACNA1D,CAMK2B,CCK,USP2,SLC16A4,SYNGR3,ENTPD2,DLGAP1,FAM189A2,IFFO1,NCOR2,CSF1,RIMS2,SPOCK3,SV2A,EDN3,AASS,OLFM1,ADAM28,RND1,POLL,GNAO1,GNG4,GRIK1,ADAMTS8,HPSE2,KCNJ4,ADAM22,MYH6,NRCAM,OLR1,ENPP2,C19orf57,RPE65,SCN3A,CNKSR2,MYH15,SNCA,ZSWIM8,SPP1,DDN,TAC1,TAL1,TRIM2,RALYL,TLR4,TPM2,CADM1" Drug 2786_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ACTN2,NDRG2,NME5,KIAA1324,BIN1,ANK1,CNTNAP1,KCNAB2,MTMR3,BAIAP3,CACNB2,CBFA2T2,RCBTB2,ASIC3,TAOK2,EPS15L1,HOMER3,AKAP7,SNPH,DMPK,CDON,C3orf18,ZNF589,GAB1,GAD2,GFER,GLS,NR3C1,ICA1,KCNB1,KCNN1,MAP4,MAPT,NDUFA5,OPRL1,PLCD1,PPP5C,RELN,PTPRN2,ENOX1,RPS6KA2,RYR1,SCN8A,STUM,KDM4B,ZCCHC24,ZC3H13,ARC,SYN2,POPDC3,WSCD1,PCDHGA10,TK2,TPM3,CADM1,FLRT2,TFIP11,SEMA3B,SLC17A7" Drug 3686_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "ASPHD1,NDRG2,SLC12A5,NME5,PPP4R4,ATP2A2,ATP6V0A1,ADAM23,GYG2,CFAP410,USP2,MAGI1,CHI3L2,CHRNB2,AATK,EDRF1,CYBB,RIMS3,SHANK1,EGFR,EPHA5,GATM,ALDH1L1,GFER,PRUNE2,GRIK2,GRM1,ICA1,IL12A,MARK1,MMP16,NHLH1,ODF2,OMG,PDE2A,PIK3CD,PNMA3,POU3F4,MAPK8,ZSCAN32,RFX2,RAVER2,SALL1,HKDC1,SLC1A6,NFASC,PCDHGA10,DOCK9,THBS4,RIMBP2,TRIO,TRO,UCHL1,OSBP2,ZIC3,TRIM9,MKRN3,PRDM2,KCNAB1" Drug 2568_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.48E-07 1.71E-02 1.11E-05 1.27E-04 59 197 "KIDINS220,NR0B1,AMH,BIN1,ANK3,APBB2,BMP7,FUBP1,CACNA1G,MAGI1,GPR37L1,CHGA,CHRNA4,EPS15L1,ZFYVE9,CNN3,CRYBB1,VCAN,NCAN,PDE4DIP,RIPOR2,C3orf18,COQ7,ZNF549,IQCG,PDLIM5,SIGLEC8,ADAM28,C1QL1,LYVE1,GPD1,PRUNE2,GRM8,SOX21,GUCY1B1,HNMT,TJAP1,ITIH2,KCNF1,KCNQ3,LAMA2,PACRG,MAP4,MDFI,NNAT,NUMA1,PBX1,STRN3,POU6F1,PPP2R2B,PTPRG,PID1,FAM214B,PEG10,RAP1GAP2,MCF2L,AHCYL2,RBFOX2,KCNK12" Drug 7097_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.49E-07 1.71E-02 1.11E-05 1.27E-04 57 188 "RIPK1,CFLAR,CNOT8,KIAA1549L,ARMC8,WHRN,ABI3BP,CHD1L,HINFP,TENM4,DCAF4,ZFYVE16,ZNF337,GIT2,KMT5B,EIF5,ETV1,WAC,CHST15,TRAF3IP2,INPP5K,GLS,FERMT2,GUCY1A1,GUCY1B1,MKLN1,NEK1,NPR2,OGG1,PLCD1,PPP5C,TMEM104,CCDC25,SBF1,ST6GAL1,RAB3GAP1,CCDC88A,TTC17,PDZD2,TNIK,SS18,CEP68,MTCL1,MGRN1,TCF7L2,TRIM2,ARHGEF12,TK2,KAT6B,ZNF23,TRIM9,NDRG4,ZNF189,CIAPIN1,VPS35L,SMIM8,ACTR3B" Drug CID000004597 o-nitrophenyl beta-D-fucopyranoside Stitch 3.60E-07 1.77E-02 1.15E-05 1.31E-04 30 75 "AP2A1,AP2A2,AMPH,NUMB,SYNJ1,HIP1R,REPS2,NUMBL,EPS15L1,CLTC,SNAP91,DNM1,DNM2,DNM1L,SH3YL1,GALC,AGFG1,NPY,OCRL,OPA1,SERPINE2,EPN1,EPN2,BEX1,SYP,SYT1,EHBP1,SYNE1,TF,WIPF1" Drug CID000656723 LY382884 Stitch 3.73E-07 1.83E-02 1.19E-05 1.35E-04 13 19 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM8" Drug CID000164073 Pkcs Stitch 3.73E-07 1.83E-02 1.19E-05 1.35E-04 62 211 "DGKZ,DGKD,CALM1,CCK,KRIT1,CDC42,CHN1,CHN2,CHRM1,AKAP5,AKAP12,DGKG,DAPK3,PARD6A,RASGRP1,EGFR,ERBB4,PTK2B,TUBB4A,FGF1,PSD2,GAP43,MALT1,RAB40B,MYLK2,SCIN,ITGAM,ASPRV1,MARK3,MBP,NEUROD1,NRGN,PIK3C2A,PIK3CD,PIK3R1,PKM,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK10,PSMA6,PTH1R,PTK2,S100B,MAPK12,SMPD3,RPH3A,ARFGAP1,CDK5RAP2,RIMS1,NSFL1C,SYT1,TRH,VAV1,P2RY12,RICTOR,WNK1" Drug CID000000765 9-beta-D-arabinofuranosylguanine Stitch 3.80E-07 1.86E-02 1.21E-05 1.38E-04 187 845 "ACTN1,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,NME5,APBB1,APLP1,ARHGDIA,PDE8B,ALDH7A1,RGS11,ARHGEF7,CACNA1B,CACNA1E,NGB,SLC25A14,ARHGEF25,CCK,CCKBR,KRIT1,AIFM1,ARHGEF1,ENTPD2,LRBA,ARHGEF2,CDC42,CDR1,CHRM1,RAB33A,RAB28,MYL6B,CLTC,LETMD1,ENTPD4,GDA,RGS6,LRIG1,PLCXD3,GPSM1,CYBB,DOCK4,RHOBTB1,PARD6A,DNM1,SLC29A4,DNM2,DOCK2,DNM1L,EDN1,EEF1A2,RASGRP1,RASA4,BSCL2,TUBD1,DMTN,TLR7,RRAGB,GMPR2,TUBB3,TUBB4A,ACTL6B,BAIAP2,POLK,FOXG1,AGAP2,AGAP3,RASL10A,ARFGAP2,NCKAP1,IQGAP2,TUBA8,ARFIP1,GFAP,BRD8,GK,RND1,RAB40B,GNAL,GNAO1,GNAS,GNG3,GOLGB1,GPM6A,LPAR4,MCHR1,TUBA1C,RAPGEF1,GRIA2,PLCD4,GRIK1,GRM3,CIT,GUCY1A2,GUCY1A1,GUCY1B1,GPR45,HRH3,TNFAIP8L3,SYNPO,TUBB2B,KCNJ3,KCNMA1,MAPT,SYT9,MX1,MYL3,NCF2,NF1,NME4,NOS1,NPY,NPPA,NPR2,NUCB1,NUMA1,OMG,SNTG1,PCMT1,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PIK3R1,PLCB2,PLCD1,POLG,PPP1R1A,PRKACB,PRKCB,PRKCG,PRKCZ,MAPK3,RELN,PTK2,PYGM,RAB3A,RAP1GDS1,REV3L,RGS4,RGS7,RGS12,RNASE1,GSTCD,ROM1,MRAS,NAPB,TMEM132D,SNAP25,SNCA,HECW1,SST,NSFL1C,PLCB1,MCF2L,EXOC7,TBL1X,SMG6,TIAM1,TK2,ACTR6,ZFP91,METTL3,TRIO,TSC2,TUBB2A,TUBB1,VAV1,VAV2,SLC26A10,PLPPR5,TUBA1A,PLD4" Drug ctd:C008493 methylselenic acid CTD 3.82E-07 1.87E-02 1.21E-05 1.38E-04 104 413 "ADD3,ALAD,AMT,ANK2,ANK3,PPFIA1,CDC14B,CDK10,NCOA1,ATP2A2,BACH1,CFLAR,WASF1,CALM1,CAMK2G,CAST,CCK,ARHGEF2,CDC42,RAB28,CLU,DNAJB5,QKI,MYRIP,AKAP12,NCOR1,NCOR2,FEZ1,RIMS3,HEPH,DYNC1I1,DPYSL2,DTNA,ECM2,E2F5,EDNRA,EDNRB,OPTN,MBNL2,EIF4G2,ENO2,EPB41L2,STX2,EPS8,DLC1,FOXO3,FLNC,SORBS1,FYN,ZNF274,HPGDS,FERMT2,GPR37,RAPGEF4,NR3C1,GSN,FAM107A,GUCY1A1,IFI16,IGF1,JAK1,KCNH2,MAPT,MEF2C,MITF,ADAM22,MXI1,NME4,PBX1,CDK18,SERPINE2,PMS2,PPM1B,PRKCB,MAPK3,MAPK8,MAPK9,RGS10,HSPA4L,SGK1,SH3BGR,SLC14A1,SMARCA4,SMARCD3,SMARCE1,SNAP25,ZCCHC24,FNBP1,SPTAN1,RGL1,STX1A,ADGRL3,TBL1X,ITGB3BP,GPR161,TGFBR3,TPM1,SSBP2,CADM1,WNT7A,ZNF24,REEP1,KCNAB1,ST7" Drug 4788_UP Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.84E-07 1.88E-02 1.22E-05 1.39E-04 58 193 "RALGAPA1,ACTN2,FZD9,C1QTNF3,AMPD3,GAS7,APOC1,BRINP2,SGCE,SCARB1,ASIC3,PLEKHB1,CHD1L,RIMS3,SLC12A6,EGR3,SPEG,ACSL4,FGF13,B3GAT1,HBS1L,ERAP1,RND1,GLS,GPM6A,GRB10,NR3C1,TJAP1,JAK2,KCNH2,KCNMA1,CD200,ADAM22,NF1,NUMA1,SNTG1,ZSCAN32,PTPRE,PTPRN2,C1orf54,TRIM68,GSTCD,EMID1,PPP1R9A,ASAP3,RPH3A,SLN,KDM4B,EXOC7,TBL1X,TRIM2,AHCYL2,TGFBR3,TNS1,CLDND1,SLC30A3,EVI5,NAV2" Drug 3708_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.84E-07 1.88E-02 1.22E-05 1.39E-04 58 193 "DPF1,NDRG2,ADD2,BEGAIN,AMPH,PPFIA4,APP,AQP4,SLC4A4,SLC2A11,NRP2,CA8,CLDN10,TPP1,CNTFR,CSF1,ERC2,ARNT2,ATN1,EDNRA,FCF1,EGFR,TNK2,EPHA5,CEND1,F5,DLC1,GFER,GLI2,GSTM5,PADI2,VWA5A,MMP16,ADAM22,NF1,NTRK3,PALM,PDE4D,MAPK10,RALGDS,STK32B,KCNIP1,BCAN,DZIP1,PEX26,SNCA,SCN3B,ARC,TACR1,ADGRL3,CRTC1,AHCYL2,UCHL1,OSBP2,VSNL1,LAT2,STMN4,RNF146" Drug 1363_DN Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Down 3.84E-07 1.88E-02 1.22E-05 1.39E-04 58 193 "ASIC1,ADD2,AK2,OGT,CDC42BPA,ATM,STX16,N4BP2L1,ADAM15,CFLAR,LRRFIP1,SRSF11,CHRNB2,TAOK2,ZFYVE9,CLCN3,DAPK1,PHF20L1,SUGP2,APH1A,ABI2,KCTD3,IRAK4,RASGRP2,TESK2,C1orf61,SEMA4D,TRMO,FAM49B,ZNF44,HTATSF1,OS9,CACFD1,AFF1,NEFH,NF1,NOS1,PDE4A,PIK3CD,PMS2,MAPK10,PEX5,AMBRA1,SLC11A1,UNC5B,CAMTA2,KANK1,GANAB,GSE1,TAF6,PDLIM2,DICER1,TK2,KAT6B,TNS1,WBP2,HPS4,MPPE1" Drug CID003899541 DNQX Stitch 4.02E-07 1.97E-02 1.28E-05 1.45E-04 32 83 "SLC12A5,CACNA2D1,GPHN,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GFAP,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,NUCB1,PDYN,MAPK10,ENOX1,SLC6A1,SYP,MAP3K12" Drug 1752_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; HL60; HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 55 180 "NDRG2,GRAMD1B,BIN1,EP400,PDXK,ARRB2,DNAH17,MTMR3,CD86,LRRFIP1,CHN2,AKAP7,CREM,AATK,MICAL2,PPP1R16B,RUBCN,DOCK4,DNM2,FAM13A,PADI2,PACSIN2,MAN1B1,MAN2A2,NUCB1,OGDH,OLR1,PDE4B,GPSM2,SMOX,PPP2R2B,PTPA,PTK2,RAB5B,SATB1,SGK1,SLC11A1,ELMO2,KDM4B,ZSWIM8,BEX1,SPTAN1,SAMSN1,EPB41L3,STX1A,PLCB1,NSD1,SIK3,THBS4,TRPM2,FLRT2,PLPPR2,MICAL1,WIPF2,PDSS2" Drug 426_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NDRG2,PLA2G6,APC,ARRB1,ARSF,SLC4A4,ADAM23,ADAM15,ARHGEF7,CBFA2T2,CHRM4,CLCN3,CNTFR,ABCG1,AATK,MED12,SIDT2,SORBS3,EPB41L2,STX2,TUBB4A,TRMO,POMT1,PDLIM5,TBR1,ALDH1L1,RUNDC3A,GLYR1,CNTRL,BTN2A1,PTPRT,GSN,SCIN,ITIH2,KHK,MBNL1,MYO6,PFKFB3,CCSER2,MBOAT7,MTMR10,RNASEL,RXRA,SH3BP2,SLC2A5,PKNOX2,SNCA,NMNAT2,MYCBP2,RAP1GAP2,SSTR2,NXT2,ZFR2,PLCB1,TRIO,TMPRSS5,VAV2,NDRG4,VPS35L" Drug 1689_UP Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "TRMT9B,APBA2,APC,APLP1,SEMA4G,SLC4A4,SLC2A11,CFLAR,SYNJ1,LDLRAD4,QKI,HOMER3,SLC4A8,SH2B1,GPRASP1,ATN1,DTNA,EFNA3,COQ7,DMTN,F5,ZNF589,FGFR1,FHL1,GAB1,GAD2,GART,TXNL4A,ELOVL5,ZNF862,NF1,NFYA,NUMA1,KCNK10,PLP1,PPP2R5C,GSTCD,RYR1,ABLIM3,PREX2,PKNOX2,SMARCC2,SMARCD3,TSNAXIP1,EMC1,SPTAN1,ZBTB43,TROVE2,SAMSN1,CEP68,PLCB1,TCF7L2,ZNF34,HEY2,ZKSCAN5,VIPR2,REEP1,WNK1,PRDM2" Drug 4147_UP Xylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN2,ADGRF5,MRTFA,BEGAIN,AMH,CDK13,ATP2B2,CFLAR,CACNA1I,RUNX1T1,CLDN10,JAM2,EPS15L1,SLC24A2,AKAP7,VCAN,DAPK1,CTIF,DNAJC6,DCT,HS3ST2,DYNC1I1,RCAN2,SPEG,OGA,GAP43,PRUNE2,KCNB1,KCNMA1,LIFR,TAGLN3,MYBPC1,NCAM1,NNAT,NOVA2,NTRK3,PDE2A,CAMKV,PIK3CD,PSD,SLC2A5,PKNOX2,RIMS1,FAIM2,SOX2,KIF21B,DOK5,NPAS3,LMO3,ATP10B,SYN2,WSCD1,PCDHGA10,SLC35G2,DNAH7,CLIP2,LAT2,SLC30A3,SMIM8" Drug 3976_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "FZD9,ADGRF5,AMT,ANK2,CNTNAP1,GAS7,CACNA1I,CACNA1G,CACNG1,CAMK2B,RUNX1T1,JAM2,TCEAL2,VCAN,RIPOR2,SPOCK2,DCT,DMD,TRAPPC9,ST8SIA3,EDN3,AASS,OLIG2,FGFR1,GAP43,RUNDC3A,POLL,GNAO1,SOX21,PTGDR2,HLF,TJAP1,KCNMA1,ADAM22,NTRK2,PDE4B,PDE1B,PPP1R1A,MAPK7,DCHS2,GDPD2,PTPRZ1,KHDRBS2,TRIM68,NUDT11,BCAN,PKNOX2,FAIM2,HECW1,PHLDB1,AJAP1,PCDHGA10,DOCK9,HIF3A,PIK3R5,AMACR,UBE3A,ZNF711,MKRN3" Drug 2577_UP Merbromin [129-16-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "BIN1,APP,SPTBN4,BMP7,CALB2,CBR1,CDC27,CDO1,CHM,CLCN3,SLC4A7,CSNK1E,VCAN,PDE4DIP,CNTNAP2,USP6NL,DAPK3,DBT,RHOBTB1,E2F5,COQ7,CDKL3,CEND1,PTK2B,GPR153,GALC,ZNF276,GPD2,GPR22,GRIK2,GSN,PADI2,NCKAP1L,KHK,KIF5A,LIG4,NEK1,CNOT4,NTRK2,NUMA1,P2RY1,PDE3B,MAPK8,BCAS3,RPH3A,CCDC88A,SNCA,ZHX3,SPP1,NXT2,PCDHGA10,AHCYL2,PIK3R5,RBFOX2,UGT8,BEST1,ZBTB38,SH3GLB2,PRDM2" Drug 6200_UP "estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN2,BIN1,CDC14B,CDK10,SLC4A4,ATP6V0A1,BCL2L2,CFLAR,BMP7,CBFA2T2,CLCN4,NCOR2,CSF1,ARHGEF10,NCAN,PDE4DIP,DAPK1,DAPK3,SEZ6L2,SGK2,SORBS3,TNK2,MRNIP,C3orf18,VPS13B,ANKMY1,BAIAP2,AGAP2,SORBS1,GPR153,SEPT9,KCNJ5,KHK,MDFI,MYO7A,CNOT4,NPTX1,PCBP3,TREM2,RETREG1,MAPK7,MASP1,RAB3A,WLS,CPEB3,SLC1A7,PALLD,KDM4B,LHPP,MAPK8IP3,RPGRIP1L,PCDHGA10,TNNT1,TPM3,TRPC3,LMF1,PRDM10,TIGD6,SSPN" Drug 3767_UP Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,AP2A2,C1QTNF3,AMPH,APAF1,STX16,FUBP1,SYNGR3,CHI3L2,WHRN,IFFO1,TCEAL2,FEZ1,CNTNAP2,DAPK1,MFAP3L,SPOCK3,DRD1,MRNIP,CDKL3,CEND1,PDLIM5,NSG1,ALDH1L1,RUNDC3A,RAB30,GNAO1,GNG3,GRM1,ITIH2,KCNB1,KCNJ5,KCNK2,KCNN1,KIT,MEF2C,MGAT3,MMP17,MT1M,NRCAM,TNPO2,MAPK8,PTAFR,ACSM5,RGS3,SYNDIG1,PAQR6,SH3BP2,DOCK10,PPP4R3A,SHANK2,SPTB,SSTR2,MCF2L,TF,PIK3R5,PDIA2,PRDM2,ADAMTS9" Drug 4066_DN Xylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASPHD1,MTUS1,AMPD3,CDC14B,MARK4,ASTN1,NOL4,ATP6V0A1,NRP2,BAIAP3,LDLRAD4,CACNB2,CACNG1,LHX2,DNAJB5,TCEAL2,CREB5,PDE4DIP,MFAP3L,SGK2,PLXNC1,CORO2B,DLC1,ST3GAL6,FGFR1,EFCAB2,C1QL1,GNAL,GPM6B,IL6ST,INPP5B,KIFC3,MAPT,ADAM22,ZNF862,NNAT,NOVA2,OPCML,RETREG1,NLE1,CDIP1,CNNM2,FAM120C,ZMAT4,CCDC102B,TCP11L1,MAP6D1,MRAS,URGCP,ACSBG1,MCF2L,KIAA0930,SYNE1,CRTC1,TRIO,TRPC3,ZMYND8,HIRA,STMN4" Drug 6395_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,NME5,BIN1,CNTNAP1,APAF1,APC,APLP1,SPTBN4,MTMR3,LDLRAD4,CLDN10,FOXN3,LY86,PICK1,DGKG,DAPK3,CTIF,RUSC2,EN2,EFS,PTK2B,KIAA1109,C1orf61,AGAP2,KHDRBS3,GAD1,GAP43,SRCAP,GFER,C1QL1,GLYR1,GNG4,PRUNE2,GPR37,IL11RA,KCNA4,KCNH2,MAP2,MMP16,MYT1,NTRK3,SNTG1,LRP12,PRKAR1B,MAPK7,PLPPR1,FAT4,RFX2,ASAP3,SNCA,DOP1A,ZCCHC24,PCDHGA10,GPR161,SLC44A1,TK2,PDIA2,ADAMTS9,KCNAB1" Drug 3663_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "SYN3,ADD2,BRINP2,LDLRAD4,CFAP410,CAMK2B,CDC42,KCNAB3,CHRNB2,AKAP5,IPCEF1,ST18,RIMS3,SPOCK3,ARNT2,DTNB,SNX29,EFNB3,RGS17,PIPOX,DLC1,HPCAL4,PDLIM5,NSG1,GAB1,GAP43,GPM6B,LILRA2,PADI2,HTR2A,IGSF1,ITPKA,KCNN1,LAMA2,MARK1,AFDN,CD200,ADAM22,MYBPC1,NELL2,NPTX1,CDK18,GDAP1L1,PIK3CD,FXYD1,NECAB2,PTPRD,RORB,SALL1,SH3BP2,PPM1E,NFASC,AJAP1,MLC1,SYNE1,TEX15,TUBB1,SLC17A7,PAK5" Drug 3910_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASIC1,ADORA1,ADORA2A,ALCAM,BIN1,CNTNAP1,APAF1,GAS7,ARHGDIG,NUMB,SLC4A4,N4BP2L1,LDLRAD4,CDC42,CHRNB2,ARHGEF6,AATK,GREB1,ARHGEF4,SEC14L5,ATN1,EDN3,RASGRP2,KCNMB2,FGFR1,PDLIM5,KHDRBS3,GAB1,TMEM8B,GLYR1,POLL,GRM2,IL1RAPL1,HSF2,L1CAM,MAPT,MYT1,NOS1,PCSK2,MAPK7,SNRK,PTAFR,ZDHHC14,RNASE1,ASIC4,SLC2A5,ARHGEF40,KDM4B,BEX1,NCDN,MAPK8IP3,PCDHA5,TMOD1,TPM2,LAT2,SLC30A3,HPS4,PARP11,ST7" Drug 6014_UP Pivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "APC,AQP4,RASL11B,CFLAR,SCAPER,BAIAP3,CA4,CA12,CACNA1D,CACNB4,PTBP2,NEURL1,RCBTB2,DNAJB5,WHRN,CSF1,VCAN,TMCC2,DLG3,DMPK,DTNA,HIPK3,COQ7,ZNF391,CACNG2,FOXG1,TBR1,GFER,GRK4,PCLO,GUCY1A2,PTGDR2,ATXN2L,KLF12,ICA1,SHISAL1,KCNJ5,KCNN2,TM6SF1,MID1,RETREG1,PLCD1,PURG,PPARA,MAPK10,GRAMD1C,RELN,TCP11L1,SH3BP2,CPEB3,KIF21B,VAMP1,PIK3R5,RUNDC3B,TRPM2,SYNC,SLC17A7,FAM13C,JPH3" Drug 4326_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADCY2,SLC12A5,AQP6,CDK10,ASPH,ADAM15,ST3GAL5,CFAP410,CACNB2,ARHGEF2,LARGE1,CHI3L2,MYRIP,ABCG1,SUSD5,CYBB,SMG7,SV2B,AK5,PLXNC1,OLFM1,FOXF2,PRELID3A,ADAM28,GPER1,PADI2,KLF12,HLF,LMO2,LSS,MSI1,PALM,TNPO2,PTAFR,CCDC40,ENOX1,TMEM206,ZNF821,MRAS,SH3BP2,ASAP3,HKDC1,PKNOX2,SLC11A1,ZBTB43,RBM26,ACSBG1,ARC,MCF2L,CRTC1,GPR161,AMACR,TRO,XRCC4,SF1,NT5M,KCNAB1,EPM2A,CAMK1G" Drug 2564_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NDRG2,ADORA3,AP2A2,ARHGDIG,PROM1,CFAP410,THSD7A,HIP1R,MAP7,ADGRG1,CHRNB2,CLCN4,WHRN,COL9A3,RIMS2,RIPOR2,DTNB,FAM13A,TNK2,SRPK3,COQ7,RASGRP2,ANKMY1,CORO2B,CAMKK2,GAD1,ALDH1L1,ADAM28,ATF7,PADI2,KLF12,HTR5A,TJAP1,KIT,MAPT,SERPINE2,SLC25A23,PTPRN2,GAL3ST4,ZNF821,PREX2,SLC11A1,HECW1,ARHGAP26,SPTB,RAP1GAP2,SPART,DNMBP,DOCK9,TJP1,TMOD1,PARD3,RBFOX2,ZMYND8,TUBB1,FLRT1,LAT2,SENP7,JPH3" Drug 7322_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADORA2A,NME5,AMPD3,APBB2,ASPH,RASL11B,ALDH7A1,SCAPER,BRSK2,ARHGEF6,CNTFR,AKAP7,CSF1R,ARHGEF10,PARD6A,DTNA,EFNA3,VPS13B,F3,DLC1,CAMSAP1,PRELID3A,CSDC2,TXNL4A,CACFD1,ATXN2L,ELOVL5,INPP5B,KCNJ3,MAPT,ADAM22,NF1,NOS1,NUMA1,MTRF1L,POU6F1,GON4L,TMEM104,PTCH1,FAM120C,ZSCAN2,RAD52,RGS12,ZNF821,MRAS,SLC1A7,SLC20A2,LIMCH1,RBM34,TROVE2,ARHGEF9,ARHGEF12,TMPO,TNS1,TRPC1,WIPF1,ITM2C,ACTR3B,SSPN" Drug 4351_UP Quinethazone [73-49-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,CDK13,MARK4,N4BP2L1,CFLAR,BMPR1B,RUNX1T1,CCKBR,CBFA2T2,CBARP,CHI3L2,CLCN4,SULT4A1,CNTN1,MICAL2,CNTNAP2,NOS1AP,PHYHIP,SPOCK2,CTIF,SGK2,EN2,KCNMB2,APC2,REEP2,NSG1,GPER1,GRM7,IGF1,KCNMA1,LMO1,MAPT,MARK1,MBP,TAGLN3,MX1,PIK3CD,PRKCB,MASP1,RELN,PTHLH,PEX5,RGS7,KLHDC8A,MRAS,SLC14A1,SLCO1A2,SCN3B,PEG10,ZC3H13,RBM26,MLC1,SLC35G2,SEZ6L,TRIO,UCHL1,MKRN3,SLC17A7,DPF3" Drug 7451_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,ABHD6,AP2A2,LTBP4,APAF1,APP,MARK4,ALDH4A1,CACNA1D,CAMK2G,ARHGEF2,CHRNB2,STOML1,NCOR2,DCT,ATN1,RCAN1,HIPK3,F3,FAM198B,FECH,FGF12,CAMKK2,CGREF1,OGA,TRAF3IP2,SYT17,GLS,GRB10,RNFT2,MDM4,ADAM22,BCO1,LYRM9,NF1,CNOT4,PAK3,SERPINE2,PIK3CD,LRP12,PRKAR1B,PTN,FAM120C,RIPOR1,NKAIN1,SBF1,SLC6A9,CCDC88A,ZCCHC24,TROVE2,VAMP1,PLCB1,SEMA4A,EXOC7,RPGRIP1L,PCDHA6,CDK20,TRPC1,LAT2" Drug 4187_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "TTYH1,ADCY2,ASCL1,CADM3,SYNJ1,MYRF,CDK5R2,BTRC,MAP7,LARGE1,STOML1,RAB26,HOMER3,AKAP5,IFFO1,HAPLN1,CRY2,SPOCK2,DNAH9,DYNC1I1,DTNA,ING4,PLEKHO1,PDLIM5,CAMKK2,B3GAT1,GABRA2,HBS1L,ZMYND11,GAP43,PCDH17,STON1,IRF8,IGFBP1,KCND3,MEF2C,KCNK10,NECAB2,PTPRN2,GAL3ST4,RGS3,SUPT20H,PREX2,SLC2A5,SHANK2,SLC14A1,SMARCD3,SNCA,TNIK,DOK5,SOX15,ADGRL3,R3HDM1,TPM1,NSD2,WNK1,PRDM10,SLC17A7,EPM2A" Drug 5211_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADCY6,C1QTNF3,MRTFA,ALDH7A1,USP2,CBFA2T2,ZFYVE9,PICK1,CRMP1,PLCH2,CNTNAP2,CTIF,RUSC2,SMG7,DRD1,FCF1,EFNA3,MBNL2,EPB41L2,MTSS1L,CEND1,FGF12,SEMA4D,PDLIM5,CSPG5,GAD1,GLYR1,PCLO,KCNK2,KIF5C,KPNA5,SMAD1,MAP4,KITLG,ZNF862,MAPK8,RAB3IL1,RAD52,PNMA8A,ZNF821,CNKSR2,SLC1A7,KANSL3,PKNOX2,CCDC88A,LIMCH1,WDTC1,TNIK,MAPK8IP3,JMJD6,ARC,PCDHGA10,PCDHA5,AHCYL2,TRPC1,XRCC4,NT5M,MVB12B,TIGD6" Drug 5059_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ALK,AMPD3,KCNAB2,ADAM23,RGS9,CACNA1D,CBS,CCK,CRLF1,ASIC3,IQCK,CABP1,MYRIP,RIMS2,PHYHIP,DAPK3,TRAPPC9,DRP2,ATN1,ST8SIA3,COQ7,MTSS1L,APC2,FGF12,AGAP2,SIGLEC8,LYVE1,GPD1,PTGDR2,KCNN1,KIFC3,LIFR,MOBP,MYT1,NRCAM,P2RX7,ABCB1,RETREG1,SPATA6,PPARA,MAPK10,PROX1,WDR25,RGS4,RGS10,MRAS,CPEB3,DOCK10,SLA,ZNF334,SLCO1A2,DDN,TBCEL,PHF24,CHST5,TRO,RPRM,FLRT2,FAM13C" Drug 2817_DN Gelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "PPFIA3,CDK10,PPP4R4,ARHGDIG,ARRB1,ALDH4A1,RIPK1,ST3GAL5,CACNA1D,KYAT1,USP2,PLEKHB1,TAOK2,HOMER3,COL4A5,SLC4A8,CREM,CSNK1E,KIAA0513,LYPD1,SGSM2,DSCAM,EPB41L1,F3,TESK2,FGFR1,BAIAP2,IQCG,TXNL4A,NR3C1,HNMT,DHX35,KCNH2,KCNJ3,KIF5C,MAN2A2,MAP4,MATK,NFYA,NPR2,SSH1,MBOAT7,FSD1,WDR25,PEX5,RIPOR1,RAD51D,ROBO1,ZNF821,SPTAN1,FCHO1,SEPT8,MCF2L,TBL1X,TCF7L2,TRPC1,ZKSCAN5,GDPD5,PHTF2" Drug 3525_UP Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NME5,ALCAM,CDC42BPA,APBA2,ATP1A3,CADM3,CACNA1D,HIP1R,ARHGEF1,CBFA2T2,NEURL1,KCNAB3,CPS1,ENTPD4,AATK,CHD5,RIMS2,SPOCK2,CTIF,ELN,C3orf18,ATP8A1,KIAA1109,IQCG,FYB1,SIGLEC8,SEPT9,INPP5K,GATM,MALT1,GLS,GNAS,GRM3,ICA1,AFF1,ADAM22,TAGLN3,NEUROD1,NOS1,PENK,SAMD9,RAB3A,RAD52,KHDRBS2,RGS12,TCP11L1,NLGN1,FAM214B,SLC14A1,NPAS3,KAZN,ZEB1,PCDHGA10,CRTC1,TEX15,DNAH7,TNS1,LMF1,LAT2" Drug 3136_UP Trapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASIC1,AMPH,CNTNAP1,APBB2,PPP4R4,BTRC,THSD7A,CAMK2B,SLC24A2,CRY2,DZIP3,GPRASP1,SPOCK2,E2F5,SIDT2,EFNA3,LRRC23,ETV1,F5,FGFR1,FOXG1,TMEM8B,ZNF276,GLYR1,GPM6A,GPR22,KIF3A,ICA1,TJAP1,KCNA1,MAPT,AFDN,MMP16,SLCO1C1,CNOT4,PDE2A,PFKFB2,PLCD1,PRPH,BCAS3,LRRC49,PTPRN2,MAP6D1,FOXRED2,MAPK12,ZNF821,SLCO1A2,RIMS1,SNCA,NPAS3,MLC1,SYT5,WWC1,ARHGEF12,CRTC1,TRPS1,FAM155A,FLRT2,SPHK2" Drug 4546_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADCY6,ADRA1D,APBB2,ALDH4A1,TPP1,SLITRK5,SDC3,ARMCX2,PLPPR4,DLG3,EXOG,DTNA,EDNRA,CNNM1,PLXNC1,EIF5,ANKMY1,F8,FGFR1,BAIAP2,DENND2A,GAD1,GART,GRM1,GUCY1B1,TJAP1,MIA2,GIT1,MX1,NDP,CNOT4,MAPK3,MAPK7,GON4L,FAM120C,RIPOR1,RAD51D,SH3TC2,ATG16L1,MAPK12,ATXN2,SCG5,SH3GL2,FBXO11,DZIP1,SHANK2,SLC22A4,COLGALT2,MAPK8IP3,DOCK9,TNS2,CRTC1,ATP13A2,UGT8,LMF1,WIPF1,TFIP11,HPS4,SMIM8" Drug 3725_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADORA3,LTBP4,ALK,ARHGDIG,CADM3,NRP2,CFLAR,FUBP1,CACNG1,CBS,CLDN10,USP2,ADGRG1,NCOR2,FEZ1,PDE4DIP,RIMS2,PHYHIP,MFAP3L,DMPK,DTNB,ECM2,SEMA3D,RASGRP2,EPHA5,PIPOX,ZIC4,AGAP2,RUNDC3A,LILRA2,GRM8,KLF12,KCNN2,MMP17,MOBP,LYRM9,MYT1,NPPA,NTRK3,PPP2R2B,PTH1R,ZMAT4,SALL1,ZNF821,STUM,CPEB3,CNKSR2,PKNOX2,FAIM2,SCN3B,ZSWIM8,HECW1,ZC3H13,SYT5,KAZN,SLC44A1,FLRT2,LAT2,REEP1" Drug 4088_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "FZD9,NR0B1,PLA2G6,DNAH17,ATP2B2,RGS9,PROM1,KSR1,SCAPER,BAIAP3,CAMK2A,CAMK2B,NEURL1,NRXN3,STOML1,AKAP6,CABP1,CSF1R,SV2A,RABGAP1L,DRD1,EFNB3,SRPK3,RASGRP2,NCALD,AGAP2,SIGLEC8,GFER,CSDC2,GPM6A,RAPGEF4,STMN2,GRIN1,ADAMTS8,ELOVL5,HTR5A,KCND3,KCNF1,PACRG,MARK1,MMP16,ADAM22,PDE4B,GPR173,MAPK10,RFX2,RGS4,SCN2B,RPH3A,IZUMO4,ZC3H13,ATP10B,TACR1,RALYL,TLR4,PIK3R5,TUBB1,SLC30A3,MVB12B" Drug 6976_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NDRG2,SLC12A5,BIN1,APAF1,APOC1,MARK4,ADGRB2,MTMR3,CACNA1D,ARHGAP33,PDE4DIP,DZIP3,CTH,GREB1,EDRF1,GPRASP1,SNPH,MED12,ATN1,DTNA,EIF5,TNK2,ENO2,ZNF589,KIAA1109,FGF12,SORBS1,GAA,GLYR1,GLS,GNG3,INPP5B,ITPKB,LMO2,LSS,MAPT,MPP2,GIT1,ADAM22,NUMA1,PALM,PENK,ZSCAN32,RAB3IL1,GTDC1,PAQR6,ATXN7,SLC6A8,ZBTB43,VPS13A,PLCB1,TNS2,TGFBR3,ICAM5,VIPR2,LAT2,KCNK12,ZFP37,HPS4" Drug 6759_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADCY6,PLA2G6,LTBP4,APBB2,LGR5,PPP4R4,RGS11,MYRF,CFAP410,CA4,HAP1,SLC16A4,ARHGAP33,AKAP6,FAM131B,KIAA0513,DGKB,SRGAP3,DTNA,DTNB,ST8SIA3,ING4,MRNIP,REEP2,FGF12,AFF2,CHL1,ALDH1L1,SRCAP,PRUNE2,RAPGEF4,SPACA9,KLF12,ITGA7,PACRG,P2RX7,PDE4A,DCHS2,PTPRH,TMEM231,ZNF821,SLA,SLC1A7,PREX2,SLCO1A2,ZSWIM8,IQSEC2,CEP68,KAZN,EXOC7,TEX15,DICER1,TK2,TNS1,RUNDC3B,TRO,ZMYND8,DPF3,JPH3" Drug 7224_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADORA2A,NME5,SPARCL1,APBB2,ARRB1,PLA2G4C,ALDH4A1,CCDC181,ATP6V0A1,ST3GAL5,BAIAP3,CA12,CAMK2B,BRSK2,USP2,CD86,ARHGEF2,CDC42,STOML1,AKAP12,NCOR2,ARHGEF10,CHD5,TOX,RASSF2,JAKMIP2,DRD1,EDNRA,MBNL2,SPEG,KAT8,FGFR3,KHDRBS3,OGA,FYB1,ERAP1,GFAP,RND1,POLL,GRIN2C,IL6R,IL6ST,INPP5B,MITF,MYCN,MYT1,NECAB2,CRTAC1,RYR1,ZFP30,FRMPD1,PREX2,FAM214B,WDTC1,RGL1,PHLDB1,TCF7,R3HDM1,SSPN" Drug 3743_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "C1QTNF3,ALK,SLC4A4,ALDH7A1,IL33,LARGE1,STOML1,FAM189A2,ARHGAP24,CNIH3,SMG7,PARD6A,AK5,DMPK,ATN1,DTNA,SGK2,SIDT2,EIF4G2,ELAVL3,PDLIM5,USP19,RAB30,KCNMB4,GPM6B,SCIN,KCNJ5,KIF5C,MAP2,MAPT,NDP,NELL2,NF1,PCBP3,NUMA1,PDE3B,PFKFB2,PPP5C,CEP41,PRPH,GON4L,WDR25,PTCH1,C1orf54,SUSD4,BEND5,ZNF821,SLC9A5,SLC14A1,BTBD7,MLC1,SZT2,DNAH7,TNS1,HIRA,ZNF24,SPHK2,REEP1,KCNAB1" Drug 4816_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "KIDINS220,PLA2G6,SEMA6A,TRMT9B,CDC14B,CADM3,N4BP2L1,CFLAR,LDLRAD4,NEURL1,AKAP6,RIMS2,NOS1AP,RIMS3,MAGI2,TMCC2,KBTBD11,MBNL2,TNK2,F5,TUBB4A,ATP8A1,FHL1,FYB1,TMEM8B,SRCAP,GNAL,GPM6B,TDRKH,GRM8,ATXN2L,KLF12,MEF2C,ADAM22,NNAT,NPTX1,OMG,PALM,MAPK7,MAPK8,DCHS2,PLPPR1,C1orf54,EMID1,ST6GAL1,CNKSR2,RIMS1,KIF21B,IZUMO4,HECW1,JMJD6,VAMP1,ARC,PSD3,OSBP2,WIPF1,XRCC4,SLC30A3,WNK1" Drug 2772_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NDRG2,AP2A2,SEMA6A,OGT,APC,APLP1,CDK13,BACH1,ST3GAL5,BAIAP3,CACNA2D1,CDC42,ZFYVE9,FADS2,CNTN1,ABCG1,CSF1R,CSNK1E,PHF14,BRINP1,TMCC2,HIPK3,EIF4G2,EIF5,ING4,SPEG,FECH,C1orf61,GAD2,GPR22,JAK2,LIG4,MAP4,MID1,SLC25A23,MINDY2,PTPA,RAB5B,MSANTD2,ROM1,CLIP1,ASIC4,SLC1A7,PKNOX2,SLC22A4,ARHGAP26,TROVE2,FCHO1,TRIM2,ARHGEF12,CRTC1,CHST8,SLC44A1,HEY2,TRIO,LAT2,ZNF45,MARCH8,PHTF2" Drug 7375_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "NME5,ALAD,MRTFA,DDO,SHROOM2,CFLAR,HIP1R,CBFA2T2,PLEKHB1,NRXN1,DNAJB5,CRY2,CSF1,CSF1R,CTNND2,DPH1,EDNRB,EFNA3,PLXNC1,EFS,ZNF589,FGF1,ANKFY1,CGREF1,FYN,GFER,GLYR1,ATF7,LPAR4,GRIK5,TJAP1,LMO2,TAGLN3,CLDN11,PMP2,GDPD2,PTPRN2,FAM120C,ARHGEF10L,GSTCD,RPS6KA2,ASAP3,SNCA,SCN3B,DOK5,RBM26,DIP2A,PHLDB1,ACSBG1,JMJD6,NSD1,GPR161,R3HDM1,CABIN1,TRIO,AMACR,REEP1,PARP6,DPF3" Drug 6358_UP Naproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASPHD1,PPFIA3,SEMA4G,BRINP2,STX16,SYNJ2,CCNT1,SCARB1,CACNA2D2,ARMC8,SLC4A8,IFFO1,ENTPD4,ABCG1,CSNK1E,PDE4DIP,CTNND2,GPRASP1,MFAP3L,FAM13A,SUGP2,EGFR,EPB41L2,KIAA1109,FGF1,FGFR1,SCARA3,CSPG5,ZNF44,GAD2,SIGLEC8,SRCAP,GPR17,KLF12,HNMT,KIFC3,MEIS1,NDP,NPR2,NUMA1,MAPK7,PROX1,SEC61A2,TCP11L1,IL17RB,SLC1A7,ELMO2,LIMCH1,SNCA,SOX15,KDM4C,ARHGAP26,THSD1,SS18,ACSBG1,ARHGEF12,NT5M,SEMA3B,SLC17A7" Drug 3743_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "SYN3,AMPH,CDC14B,PPP4R4,BMP7,FUBP1,HAP1,CLDN10,CD86,CRLF1,TAOK2,CLCN4,TPP1,CNTNAP2,MYEF2,RCAN1,EDN1,HIPK3,FER,KIAA1109,FGFR1,AGAP2,GABRA2,SIGLEC8,SRCAP,GPD2,GRM8,TJAP1,ITPKA,KCND3,NPPA,NPTX1,OPCML,CLDN11,BCAS3,PTPRN2,RALGDS,RFX2,KCNIP1,SELL,ZNF821,FNDC3A,SLC2A5,PKNOX2,SLC20A2,RBM34,SPTAN1,SS18,ARC,ZEB1,CRTC1,TNS1,TRO,TRPC3,OSBP2,LAT2,PRDM2,PARP6,SLC17A7" Drug 2340_UP Ofloxacin [82419-36-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ABAT,ABHD6,ADD2,PLA2G6,MRTFA,APAF1,APOC1,PDXK,CCDC181,INA,CHGB,TAOK2,CNTN1,CSF1,FEZ1,CTNND1,ZFYVE16,DAPK3,SMG7,RCAN1,E2F5,EDNRB,CNNM1,EIF4G2,KAT8,ATP2C1,GABRA2,GAD2,ZMYND11,MSL3,GRIN1,INPP1,MAP4,MYT1,NF1,P2RY1,PCDHGC3,PLP1,LRP12,PPP2R5C,RAD52,RALGDS,RGS12,FERMT1,CCDC88A,KDM4B,ZC3H13,SPTAN1,CAMTA2,SYT11,KAZN,RPGRIP1L,PSD3,CRTC1,TNS1,HIRA,EMSY,PCBP4,UBE3B" Drug 3235_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADORA1,ADRA1D,CDK10,CADM3,BCL7A,CFLAR,BAIAP3,EPS15L1,WHRN,CREM,PDE4DIP,INTS1,MAML1,MFAP3L,SUGP2,IRAK4,RASGRP2,ERBB2,ANKMY1,CAMSAP1,DISC1,SRCAP,MALT1,ATXN2L,INPP1,LMO2,MAP4,MITF,MSI1,ADAM22,NDUFA5,PALM,PCDH9,PRKAR1B,GON4L,RAB3A,C1orf54,RGS12,RPS6KA2,SLC1A7,FAM214B,SLC20A2,WDTC1,ZCCHC24,ZHX3,IQSEC2,SPART,CLSTN2,SEMA4A,KIAA0930,PCDHA5,ZNF34,PIK3R5,RUNDC3B,ZKSCAN5,VIPR2,ZBTB38,SEMA3B,EPM2A" Drug 2890_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADD2,APAF1,APBB2,APOC1,ASTN1,NRP2,CFLAR,CACNA1I,CAMK2B,HIP1R,SLC16A4,CDH10,CHI3L2,WHRN,VCAN,SPOCK2,ZNF804A,DMPK,CDON,FRY,MBNL2,ELAVL3,C3orf18,APC2,ANKMY1,FOXG1,ALDH1L1,RUNDC3A,NR3C1,GUCY1A2,KLF12,ITPKA,NEUROD1,NF1,P2RY1,PDE4B,PACSIN1,PPARA,PROX1,RELN,CRTAC1,RGS12,DOCK10,SLC1A7,SLC8A1,SLN,IQSEC2,CRTC1,TF,TMEM121,SEZ6L,TRH,TTPA,FAM155A,UGT8,OSBP2,FLRT2,VAV2,XRCC4" Drug 5514_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASIC1,ABHD6,AMH,APBB2,CDK10,ARHGDIG,ATM,ADGRB1,SGCE,CA4,EPS15L1,SH2B1,CSF1R,CNTNAP2,EDRF1,SNPH,DCAF8,CNIH3,DRD1,USH1C,SGK2,EFNB3,C3orf18,LRRC23,ETV1,NRN1,KIAA1109,C1orf61,GPR153,OGA,GPM6B,GRM7,ATXN2L,HNMT,IRF8,KHK,IPO5,SLCO1C1,NFYA,SERPINI1,SLC25A23,PPP5C,MARCH1,SALL1,CNKSR2,ARHGEF40,SS18,CEP68,ZEB1,PSD3,PCDHA6,AMOT,UCHL1,FLRT1,XRCC4,ZBTB16,SLC30A3,KCNAB1,NUP214" Drug 3234_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,ADCY2,AP2A2,GAS7,ALDH7A1,BACH1,ST3GAL5,CA12,ARHGEF1,CHRNA4,FAM189A2,DNAJB5,PHF14,CTIF,ZNF804A,SPOCK3,DMPK,DRD1,ATN1,AASS,ZNF589,FGFR1,PRELID3A,GFER,GRM1,GRM3,KCND3,KCNJ5,MAN2A2,MAP2,MDFI,AFDN,CD200,MX1,PDE3B,PGAM2,PNMA3,PDZRN4,SNRK,PTPRD,RORB,SH3BP2,SLC2A5,SLC6A9,SOX2,KIF21B,SOX10,ZHX3,ZNF423,SPTB,ATP10B,ARC,ZEB1,SZT2,SLC19A3,SPX,R3HDM1,PRMT8,TRPC1" Drug 6707_UP Propofol [2078-54-8]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADD2,APC,PPP4R4,ATP6V0A1,ADAM23,BMP7,IL33,THSD7A,BRSK2,CHI3L2,ARHGAP22,DNAJB5,SULT4A1,COL9A2,CRMP1,CRY2,RGS6,SLITRK5,MYEF2,MFAP3L,ATN1,EDN3,RASGRP2,IGSF6,FGFR3,CHL1,ERAP1,GPR75,GPR19,IGF1,IGSF1,IL6R,KCNJ5,KCNQ3,NF1,OPCML,PROX1,PTPRB,RGS3,MYH14,SEMA6D,FRMPD1,FBXO11,DZIP1,SLC6A9,ZNF334,SNCA,SOX10,ZSWIM8,SPTB,COBL,TACR1,CNTN2,GPR161,TLR4,TMOD1,TNS1,CHST5,REEP1" Drug 1465_UP Troleandomycin [2751-09-9]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADORA1,SPARCL1,BIN1,KCNAB2,APBB2,APOC1,MARK4,ATP2B2,CFLAR,CACNA1I,CA4,HAP1,CD86,CDH2,CACNA2D2,PLEKHB1,CLU,WHRN,DMPK,ATN1,USH1C,EDNRB,IGSF6,F3,ZNF589,FGFR1,GAB1,GABRA2,TRAF3IP2,ALDH1L1,CACFD1,GRM1,NXPH3,KLF12,KCNH2,KCNMA1,KIF5C,KITLG,ZNF862,SLCO1C1,CDK18,CEP41,PRKAR1B,FAM184A,SLC2A5,SLN,KIF13A,ARHGAP26,EXOC7,IQCE,CRTC1,TMEM121,TK2,HEY2,CDK20,TRPM2,UCHL1,PDIA2,KCNAB1" Drug 6450_DN Flucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "AP2A2,AK2,PLA2G6,SEMA6A,SRPX,MRTFA,AMH,AMPD3,APP,ADAM15,SYNJ2,CAMK2B,ARHGAP33,PLAA,ARMC8,LRIG1,MICAL2,CNTNAP2,APPL1,DOCK4,HP1BP3,LYPD1,DLG3,DTNA,OPTN,EFNB3,PLXNC1,PLEKHO1,DMTN,PRELID3A,INPP5K,TXNL4A,MSL3,GPER1,CACFD1,HSD17B1,INPP5B,IPO5,NPTX1,P2RY1,SMOX,WDR25,ZSCAN32,RAD52,RGS10,BCAN,SLC1A7,WDTC1,TROVE2,CEP68,PSD3,TNS2,PLPPR2,VGF,MICAL1,KCNK12,HPS4,RNF170,SSPN" Drug 5096_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADD2,FAM135A,TRMT9B,GAS7,APLP1,BRINP2,ALDH4A1,ATP2B2,NRP2,ST3GAL5,SCAPER,CAPN3,ADGRG1,FOXN3,NRXN2,RAB26,IQCK,WHRN,CABP1,SH2B1,CRMP1,HAPLN1,CSF1,ARHGEF10,MICAL2,SUSD5,EXOG,C3orf18,SPEG,NRN1,KIAA1109,SORBS1,PDLIM5,GRM3,GRM8,SOX21,PTGDR2,MDFI,MMP16,PBX1,PDGFRA,DCHS2,SAMD9,SNRK,KCTD17,DZIP1,SLC4A3,BTBD7,ZBTB43,ASTN2,TAL1,TEX15,TLR4,DAAM2,TNS1,TPM1,MICAL1,SLC30A3,KCNAB1" Drug 4261_UP Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACHE,NDRG2,NR0B1,BEGAIN,ANK1,PPFIA2,ATP2B3,B3GALT2,RGS11,CACNA1G,THSD7A,TAOK2,DNAJB5,PCYT1B,FAM149A,COL9A3,ARHGEF4,CX3CR1,CTIF,DCC,MFAP3L,NTM,ATN1,ABCC9,SRPK3,EPHB1,ERBB4,EFS,MYOZ2,GLI2,GNAL,HPSE2,HPCA,HTR5A,KCNC1,KCND3,KCNH1,KCNJ9,PACRG,ADAM22,MYH7,NEFM,NEUROD1,SLCO1C1,NUMA1,PDE4A,PDE4D,SCN2B,IZUMO4,CDK19,MAPK8IP3,VAMP1,MCF2L,SPX,LILRA4,TRO,REEP1,PRDM2,NLRP3" Drug 5614_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,ASIC1,FZD9,PPP4R4,MARK4,RASL11B,CA4,CACNA1A,HAP1,CAST,CD86,ARHGAP33,RAB33A,PICK1,WHRN,TENM4,CSF1R,PHF14,RIMS2,DMPK,DTNB,ST8SIA3,SRPK3,FGF13,GAB1,GRIK1,GRM7,SOX21,ATXN2L,KCNC1,MDFI,CD200,MYL3,MYT1,NOVA1,NTRK3,PLCB2,PLCD1,MAPK10,ACSM5,CCDC40,KLHDC8A,KCNIP1,ASIC4,CPEB3,CNKSR2,SHANK2,LIMCH1,KDM4B,PHLDB1,SYT11,ARC,SYT5,POPDC3,WSCD1,ARHGEF12,HIF3A,SEZ6L,PRDM10" Drug 4446_UP 2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "KLRC4,AK2,PKP4,ASTN1,ATM,KIF1A,CFLAR,CDK5R2,CACNA1A,SULT4A1,FHL5,PDE4DIP,MAGI2,SMG7,RABGAP1L,EDNRA,PLXNC1,TENM1,ETV1,REEP2,ZNF589,FLT1,GLI2,RAB30,GLS,GNAO1,IRAK3,ATXN2L,IRF8,KCNH2,MATN3,MDFI,NOVA2,SPATA6,PILRA,CEP41,MAPK8,PTPRN,PTPRN2,SUSD4,GAL3ST4,RET,TCP11L1,KCNIP1,SH3BP2,CNKSR2,CXXC4,DDN,SYT5,MCF2L,ADGRL3,DMXL2,PCDHGA10,TEX15,TNS1,NPL,OSBP2,FLRT2,FAM13C" Drug 4584_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,PLA2G6,C1QTNF3,APC,BCAS1,ASCL1,ATP6V0A1,NRP2,CBFA2T2,ARHGEF2,CHN2,CHRNB2,TAOK2,CREM,ABCG1,VCAN,PDE4DIP,RIMS2,RABGAP1L,DTNA,EFNB3,F5,DPYSL4,ERGIC3,GAB1,ZNF44,ERAP1,ADAM28,RAB30,GNG4,CNTRL,IL1RAPL1,ICA1,ITGA7,VWA5A,LSS,SMAD1,NEK1,NF1,NOVA2,DDR2,NUMA1,OPRL1,PFKFB2,RETREG1,LRRN3,PRKAR1B,PTCH1,ZSCAN32,MARCH1,ACSS3,RASA3,ST6GAL1,PPP4R3A,SLC11A1,SNCA,ASTN2,SMG6,MKRN3" Drug 2811_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN2,KIAA1324,BIN1,SLC4A4,CADM3,BACH1,CACNB2,CAMK2G,CDC42,FOXN3,ASIC3,TAOK2,CTIF,TRAPPC9,DTNA,EDIL3,EDNRB,SPEG,CAMSAP1,FOXG1,OGA,NEU3,GFER,RND1,GLYR1,GLS,LILRA2,GRIK1,GRIK5,VWA5A,MID1,CD200,CLDN11,KCNK10,PURG,PTPRN2,PTPRO,RAB3A,RAB3IL1,RGS12,RPS6KA2,KCNIP1,RYR1,RASA3,PPP1R9A,NLGN1,SLC1A2,PREX2,SLC6A9,EMC1,ARC,SEMA4A,ZEB1,PCDHA5,HIRA,LMF1,SLC13A3,DNALI1,ITM2C" Drug 3815_UP Methimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,ACTN2,NDRG2,KIDINS220,LTBP4,FAM135A,APAF1,CACNA1G,CACNA1D,SUSD5,SMG7,AK5,DSCAM,DTNB,EDIL3,EDNRA,MBNL2,EGR3,EPB41,KCNMB2,EFS,ETV1,C1orf61,DKK3,NEU3,POLL,GPD1,GRM2,GRM7,SOX21,KLF12,MATK,KITLG,NF1,CDK18,PDE4A,PDGFRA,PTPRN2,RASGRF1,RGS4,KLHL11,SMPD3,CPEB3,FAM214B,SLC6A9,SLC11A1,NPAS3,SSTR2,MAPK8IP3,KAZN,TAL1,SEZ6L,TPM1,TPM2,CHST5,TRPC1,UCHL1,SPHK2,JPH3" Drug 2493_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "SYT13,APBB1,MARK4,ALDH4A1,CCDC181,MYOM1,BMP7,CACNA1I,BTRC,CAMK2G,NEURL1,SEPT7,CHN2,NRG2,CREM,GPRASP1,DAPK1,DCT,DLG4,OLFM1,FOXG1,AFF2,KHDRBS3,TMEM8B,GATM,GPR162,GFER,GLRB,GPD2,GPM6A,GRIN1,KLF12,IL6ST,JAK2,L1CAM,SMAD9,MPP2,KCNK10,PDE4A,MAPK7,PNMA8A,NEK11,EMID1,NLGN1,SLC1A2,EPN2,SHANK2,BTBD7,SNCA,ARHGAP26,SPTB,LHPP,PLCB1,PCDHGA10,TIAM1,TMOD1,LMF1,KLC2,SLC17A7" Drug 6304_DN Nitrendipine [39562-70-4]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "RBM10,MTUS1,EP400,APLP1,C5,KYAT1,CNOT8,ARHGAP32,SPOCK3,DLG3,FEM1B,LRRC23,DENND4A,FCGRT,TRMO,OGA,ERAP1,INPP5K,MSL3,GPR37,MAN1B1,KLF12,INPP5B,MAP4,TM6SF1,MID1,MN1,TAGLN3,NFYA,PBX1,CDIP1,FA2H,FSD1,PTPA,PRPH,CNNM2,GAL3ST4,RPS6KA2,SBF1,FAM102A,ASAP3,FUZ,COA1,TMCC1,FNBP1,STX1A,GSE1,ARHGEF9,EXOC7,IQCE,WSCD1,TNS2,AHCYL2,PARD3,CABIN1,PLPPR2,XRCC4,UPF3A,ST7" Drug 281_DN fludrocortisone acetate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN1,NDRG2,BRAP,EPB41L5,GAS7,DGKD,PPFIA3,AQP6,PRX,PDE8B,CADM3,MYRF,CH25H,INA,KCNAB3,ARHGAP33,KIAA1549L,SH2B1,CSF1,CSF1R,KLHL3,EZH1,PTK2B,OLFM1,CAP2,SEMA4D,GABRA4,RUNDC3A,GLS,GNAO1,RNFT2,ICA1,IGF1,KCND3,KCNJ5,KCNJ10,LMO1,MMP17,ADAM22,NASP,SETD4,PDCD2,RETREG1,RETREG2,SUSD4,SLA,PREX2,KBTBD4,CDK5RAP2,KDM4B,ZHX3,SRPK2,TBL1X,TCF7,AHCYL2,CRB1,SLC13A3,TFIP11,KCNAB1" Drug 5266_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN2,SLC12A5,KIDINS220,PLA2G6,SEMA6A,APC,APLP1,DNAH17,MARK4,ASPH,CA4,CACNA1D,ARHGEF2,CLGN,CRLF1,NOS1AP,RASSF2,JAKMIP2,ZNF804A,HSD17B14,ENO2,EZH1,KIAA1109,FGFR1,IQCG,RAB30,GNG4,STON1,PCLO,GRB10,CACFD1,ICA1,ITPKB,VWA5A,MATK,ADAM22,NF1,NOS1,SETD4,PLEC,MAPK8,PTPRE,TMEM231,RAD52,RGS10,ZFHX4,ZNF821,SMTN,CXXC4,ZC3H13,KAZN,TCF7,TRIM2,PCDHA5,RUNDC3B,ZKSCAN5,EMSY,EPM2A,SENP7" Drug 4425_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASIC1,ADRA1D,PLA2G6,SEMA6A,TRMT9B,BIN1,ANK1,APAF1,SEMA4G,MARK4,HAP1,CAMK2B,CCKBR,CDH8,STOML1,WHRN,IFFO1,CSF1,HDAC9,TRAPPC9,EDN1,CEND1,F5,DLC1,FGFR1,SCARA3,FOXG1,AGAP2,GAB1,TMEM8B,SIGLEC8,NEU3,GPR162,LYVE1,GLS,GPM6A,ATF7,GPER1,KCNN2,KIFC3,MAPT,ADAM22,NF1,KCNK10,PLCB2,PKN2,RFX2,TTLL7,LIMCH1,ZCCHC24,HECW1,PEG10,ARHGAP26,TMEM121,TNS1,PIK3R5,TRPM2,ITM2C,MVB12B" Drug 3730_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "CDC14B,CDK13,MTMR9,CACNA1A,CHRNB2,ZFYVE9,FAM189A2,LY86,CNTN1,IFFO1,HAPLN1,AATK,CSNK1E,ARHGAP24,AK5,DTNA,FAM13A,MBNL2,ANKMY1,FGFR1,SCARA3,PRELID3A,POLL,GPM6A,GRIK5,ICA1,SCIN,INPP5B,MAPT,MARK1,MDM4,MMP16,NFIX,NPR2,NUMA1,PC,PDPK1,PFKFB2,EPN1,FAM120C,C1orf54,ZCWPW1,BTBD7,SOX15,ZHX3,IZUMO4,COLGALT2,MLC1,VAMP1,PLCB1,SYNE1,TEX15,CHST8,TNS1,RPRM,VGF,XRCC4,NT5M,TIGD6" Drug 3568_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ADRA1B,TRMT9B,BIN1,CNTNAP1,APBA2,KCNAB2,CDK13,ALDH4A1,CCDC181,FGF17,CACNG1,CAMK2G,ENTPD2,CDH8,EPS15L1,TPP1,SNCAIP,SNPH,RIMS3,ATN1,DUSP9,USH1C,EFNA3,ERCC2,DLC1,C1orf61,FLT1,FYN,GAD2,RND1,SPACA9,GRM3,PTGDR2,HPCA,ITPKA,MAOB,CD200,MYCN,NF1,SLCO1C1,NTRK2,KCNK10,PLCD1,FAM120C,ZCWPW1,RPS6KA2,COA1,SP4,HECW1,LMO3,PHLDB1,TBCEL,DOCK9,SLC44A1,TRO,SLC17A6,MVB12B,PARP11,NUP214" Drug 4675_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ASPHD1,ADCY2,SLC12A5,LTBP4,APBB1,GAS7,CADM3,NOL4,BACH1,ADGRB2,BCL2L2,NRP2,CFLAR,BTRC,CACNG1,CBS,KCNAB3,CSF1R,PLPPR4,AK5,DRP2,CELSR3,RASGRP2,EFS,DPYSL4,CAMKK2,USP19,RUNDC3A,BACH2,KCNF1,KCNJ4,LSS,MIA2,MMP16,GIT1,ADAM22,MSR1,P2RY13,NUMA1,PBX1,ELOVL2,PTN,ACSS3,ZMAT4,PNMA8A,SCN2B,KANSL3,KDM4B,WDTC1,ZHX3,CDK19,PHLDB1,SYT11,SYN2,SEZ6L,TUBB1,NSD2,KCNK12,ZNF24" Drug 6485_UP Chrysin [480-40-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ACTN2,ASCL1,FGF17,CA4,CALB2,NEURL1,CNN3,FAM149A,SLC4A7,TENM4,VCAN,RIMS2,GPRASP1,BRINP1,HP1BP3,SRGAP3,SLC12A6,ECM2,MBNL2,EGR3,RASGRP2,EPHB1,EFS,CDKL3,TUBB4A,FGFR1,B3GAT1,OGA,HBS1L,GATM,SESN1,ZNF276,GLI2,GLYR1,GLS,POLL,HTR2A,KCNK2,VWA5A,NDUFA5,ENPP2,CDK14,SMIM7,CCDC40,KCTD17,SEMA6D,SBF1,ST6GAL1,CNKSR2,MYH15,FAIM2,NXT2,ARC,EXOC7,WSCD1,TRIM2,SLC44A1,LAT2,SSPN" Drug 4165_UP Trimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "DPF1,SYN3,LTBP4,BEGAIN,BIN1,KSR1,CALB1,CDH2,AKAP7,NCOR2,DBT,CDON,USH1C,ST8SIA3,FRY,MTSS1L,SPEG,CEND1,PTK2B,FOXG1,SORBS1,CAMKK2,OGA,FYB1,GAP43,CPLX2,GNAO1,PRUNE2,MCHR1,GRM8,LAMA2,ADAM11,MID1,CD200,TAGLN3,PCDHGC3,PFKFB2,PLTP,PTCH1,ELOVL2,RGS4,RGS12,TTLL7,ST6GAL1,ZNF334,SNCA,FAIM2,PHLDB1,MLC1,TAC3,ATP11A,TCF4,PCDHGA1,TEX15,TNS1,UBE3A,UGT8,LAT2,XRCC4" Drug 6192_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "ARID1A,ADORA1,SYT13,TRMT9B,AMH,ANK3,RASL11B,ALDH4A1,SLC4A4,MYOM1,CACNB4,CHI3L2,CHRM4,SLIT2,CDC42BPB,CRY2,CSF1,CTNND2,KLHL3,ATN1,ABCC9,EDNRA,HEYL,OPTN,SORBS3,DMTN,MTSS1L,APC2,FHL1,HPCAL4,GFRA1,GPR75,GRIK5,PTGDR2,MAP2,NEUROD2,NOS1,OPRL1,PFKFB2,ELOVL2,KLHL11,ROM1,RYR1,SH3BGR,SH3BP2,FRMPD1,ASAP3,SHANK2,INKA2,PHLDB1,ARHGEF12,TK2,DAAM2,TNS1,TRIO,TMPRSS5,ZBTB38,SCG2,SLC17A7" Drug 2541_DN Propidium iodide [25535-16-4]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.21E-07 2.06E-02 1.28E-05 1.46E-04 59 198 "TRMT9B,BIN1,MTMR3,CACNA1A,CAPN3,REPS2,TAOK2,ZFYVE9,PLAA,CSF1,PDE4DIP,DAPK3,RUSC2,CDON,EEF1A2,FEM1B,RASGRP2,CDKL3,ST3GAL6,TESK2,FHL1,CAMKK2,ZNF44,LILRA2,GRIK2,GRM1,KCNMA1,MAP4,MID1,AFF1,NF1,NUMA1,PLCD1,LRRN3,DEF8,RAB3A,RAB3IL1,RALGDS,KHDRBS2,SLC1A7,EPN2,SLC11A1,MYH15,VAMP1,SYN2,TNS2,ATP13A2,THRA,TMOD1,KCTD2,TNNT1,CDK20,TPM3,TRIO,XRCC4,ZNF32,GDPD5,FAM13C,UBE3B" Drug CID000001271 L-CCG-I Stitch 4.28E-07 2.10E-02 1.30E-05 1.48E-04 23 50 "ADORA1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNMA1,MAP4,NPY,PLIN1,SLC1A2,SLC1A3,SLC17A6" Drug CID000003150 AC1L1FA8 Stitch 4.28E-07 2.10E-02 1.30E-05 1.48E-04 23 50 "ADCY2,ADCY5,ADCY6,ADCY8,CA4,GFAP,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM3,LIG4,NUCB1,SLC1A2,SOX10,ST8SIA2" Drug CID000002252 Atpa Stitch 4.43E-07 2.17E-02 1.35E-05 1.53E-04 10 12 "EIF4G2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM2,GRM3" Drug 5255_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ASPHD1,ACTN2,NME5,AK2,SEMA6A,APBA2,EPB41L5,CFAP410,CA4,CLGN,FOXN3,HOMER3,CNTNAP2,MFAP3L,DTNA,HIPK3,FEM1B,ING4,HSD17B14,EZH1,SCML2,KAT8,FGF13,BAIAP2,FHL1,GLS,MSL3,GNG4,GPER1,GPR37,CACFD1,RASSF8,HSD17B1,KIF5A,MAPT,MPP2,ADAM22,NPTX1,P2RY1,PCDH9,RETREG1,PPP5C,CCDC25,TCP11L1,CXXC4,SNCA,WDTC1,SOX2,ZCCHC24,TROVE2,SEMA4A,TBCEL,WSCD1,TCF7L2,PSD3,TMOD1,SSBP2,EPM2A" Drug 2311_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "NME5,CFLAR,MTMR3,CACNA1A,CAMK2B,NRG2,SNCAIP,SDC3,DGKG,DMPK,SHANK1,RASGRP2,ERCC2,SPEG,PTK2B,ZNF589,OLFM1,FHL1,C1orf61,FOXF2,GAD2,LYVE1,PRUNE2,GRIA4,SOX21,HTR2A,IGFBP1,ITIH2,KCND3,MBD1,KITLG,CD200,ADAM22,BCO1,MX1,SLCO1C1,NTRK2,PLCB2,PPARA,PTCH1,ZFHX4,PLPPR3,SELL,STUM,SLC11A1,OGDHL,LIMCH1,SPP1,ARC,TBCEL,SEZ6L,AMACR,TRO,VAV2,DNALI1,SLC17A7,KCNAB1,ST7" Drug 2687_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "MTUS1,NR0B1,AMPD3,ASPH,ATP2B2,AZGP1,RGS11,NEURL1,CDH10,GPR37L1,CHGA,CHI3L2,CABP1,COL9A3,SUSD5,PDE4DIP,CNTNAP2,DZIP3,DGKG,MYEF2,ST8SIA3,AASS,SORBS3,SRPK3,EPB41,FAM198B,FER,BAIAP2,AGAP2,GCNT2,GFER,GNAS,GPM6B,GRK4,GPR45,HNMT,KCND3,KCNJ5,MATN2,ADAM22,SCG3,NEFM,PMP2,ZSCAN2,RASGRF1,SUGCT,KLHDC8A,SH3GL2,ZNF415,ZNF423,ACSBG1,SYT5,GPR161,TRIO,TRPS1,MAP3K12,EVI5,JPH3" Drug 2993_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ABHD6,NDRG2,SEMA6A,BIN1,ST3GAL5,HIP1R,RAB26,CPS1,PDE4DIP,DOCK4,GPRASP1,RIMS3,DNAJC6,MAGI2,GSDME,TMCC2,HIPK3,SRPK3,OLIG2,ETV1,TLR7,TBC1D16,FHL1,FYB1,GAD1,INPP5K,GATM,ADAM28,PCDH17,STON1,SCIN,ITGA7,KHK,KIF5C,MDM4,MEF2C,NCAM1,SERPINI1,PLCL1,PPP2R2B,PRKAR1B,TMEM255A,FAM184A,DOP1A,TNIK,ELOVL4,RGL1,STXBP1,DNMBP,CAMSAP2,ADGRL3,TBCEL,PCDHGA10,TPM3,SSBP2,CLIP2,KLC2,FZD3" Drug 5531_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ADCY2,BEGAIN,APAF1,APBA2,CDK10,CACNA1D,CACNA2D1,NEURL1,CLGN,SLC24A2,CPS1,C2CD2,ENTPD4,VCAN,RIMS2,EDRF1,GPRASP1,SPOCK2,HP1BP3,SMG7,FCF1,SIDT2,C3orf18,ENO2,DCTN2,INPP5K,NR3C1,HNMT,INPP5B,KCND3,LAMA2,LIG4,NPTX1,NTRK3,CAMKV,RETREG1,STRN3,PACSIN1,PPP5C,GON4L,SNRK,ELOVL2,TTLL7,PNMA8A,RPS6KA2,FRMPD1,SLA,PEG10,RBM26,STX1A,MCF2L,TBL1X,WSCD1,HIRA,VAV2,XRCC4,MAP3K12,EMSY" Drug 3938_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "KIAA1324,ALK,BEGAIN,TRMT9B,BIN1,PDE8B,SEPT7,CDH10,CHRNB2,TPP1,LY86,WHRN,CRY2,GSDME,SV2B,NTM,IGSF6,ST3GAL6,FGFR1,FOXG1,DCTN2,NEU3,POLL,GNAL,PRUNE2,GRM8,MGAT3,MOBP,P2RX7,KCNK10,TREM2,DUSP26,CAMKV,PDZRN4,POU3F2,PPP1R1A,PTAFR,KHDRBS2,ZFHX4,FRMPD1,SLC1A7,KANSL3,PKNOX2,SLC6A9,KDM4D,SLC11A1,HECW1,NPAS3,ATP11A,TCF4,SZT2,DOCK9,TTPA,UBE3A,ZNF711,MVB12B,KAT6A,TIGD6" Drug 5836_UP Streptozotocin [18883-66-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "BIN1,APBB2,LGR5,SEMA4G,CFLAR,ST3GAL5,SCAPER,CACNA1I,C5,CDC42,CNOT8,ABCG2,QKI,CNTNAP2,ZNF337,DAPK3,MYEF2,CNIH3,FAM13A,EPHA5,ETV1,FCGRT,ZNF589,FOXG1,SEMA4D,TRMO,FYB1,ERAP1,SRCAP,MAN2A2,MAPT,ADAM22,TAGLN3,LYRM9,ZNF426,PPARA,BCAS3,APTX,PTCH1,BEND5,ROM1,TCP11L1,RXRA,SUPT20H,KBTBD4,TMCC1,WDTC1,CAND2,BEX1,IQSEC2,STX1A,THRA,DAAM2,HIRA,WIPF1,EVI5,KCNAB1,RNF146" Drug 3716_UP Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ASPHD1,LTBP4,SEMA7A,BCAS1,APP,SLC2A11,CA12,ARHGAP33,CHI3L2,TAOK2,CLTB,SULT4A1,IFFO1,CRY2,CSF1,RIMS3,DAPK3,RABGAP1L,HS3ST2,DTNA,DUSP9,HEYL,EFNB3,CDKL3,KIAA1109,FYB1,ZNF44,HBS1L,B4GALNT1,GNAL,GPR19,GRIN2C,HRH3,KCNN2,KCNQ3,MYL3,NPTX1,PALM,PCDH9,POU3F4,PPARA,PBRM1,MYH14,PEX26,SLC15A2,ZSWIM8,NFASC,INKA2,MAPK8IP3,ARC,SYT5,TAL1,DMXL2,SLC44A1,TNS1,CDK20,LAT2,REEP1" Drug 4488_DN Amrinone [60719-84-8]; Down 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ALK,MRTFA,DOC2A,APBB1,APLP1,CDK10,ADGRB2,CFLAR,SCAPER,MYRF,FOXN3,NMT2,AKAP7,WHRN,CREB5,ABCG1,KIAA0513,DTNA,TNK2,PLEKHO1,DMTN,LRRC23,FGF1,FGFR1,FAM49B,DENND2A,SYT17,POLL,MAPT,NUMA1,MAPK8,RAB5B,ATG16L1,RAP1GAP,CLIP1,SH3BP2,ASAP3,LIMS2,FAM214B,CCDC88A,SLC9A5,ZNF667,COA1,MYH15,KDM4B,EMC1,SPTAN1,SPTB,JMJD6,ASTN2,SYNE1,GPR161,TNS1,HIRA,MICAL1,LAT2,WNK1,SEMA3B" Drug 1213_UP 17-DMAG; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "ADCY2,OSBPL1A,ANK3,PPFIA3,PDE8B,SLC4A4,KIF1A,CFLAR,CFAP410,CHN2,CLU,ARMC8,WHRN,COL9A3,ENTPD4,EDRF1,PHYHIP,ARNT2,ECM2,ING4,TUBB4A,CAP2,OGA,USP19,MSL3,PRUNE2,DIDO1,ICA1,SHISAL1,MMP16,NAP1L2,NELL2,OXTR,PBX1,PPARA,PTN,CCDC40,RALGDS,GAL3ST4,RGS4,RGS7,RGS10,PNMA8A,TMEM206,SUPT20H,HSPA4L,DOCK10,SMARCD3,PDZD2,ZC3H13,IQSEC2,COBL,TRIM2,CABIN1,TNS1,HPS4,SMIM8,FXR1" Drug 3906_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "APAF1,APC,AQP4,ARHGDIG,ASPH,MYRF,CACNA2D1,RCBTB2,CHRNB2,ARHGEF6,CNTFR,CABP1,SEC14L5,SPOCK3,CDON,DTNB,DYRK1A,CEND1,FGFR1,KHDRBS3,FYN,GLS,PRUNE2,PCLO,GRM1,HRH3,KLF12,TJAP1,KIT,LMO2,LSS,MOBP,CD200,ZNF862,NINJ2,NNAT,NOVA2,OPCML,CLDN11,PDE4B,SERPINI1,PLCD1,PTPRH,TRIM68,RPS6KA2,SCN8A,ZCCHC24,ELOVL4,HEY2,TMOD1,PIK3R5,TRO,CA14,LAT2,EMSY,NT5M,KAT6A,SSPN" Drug 4709_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "NME5,PLA2G6,SPARCL1,APC,APLP1,CDK13,ASPH,CFLAR,GYG2,CAMK2B,MAGI1,TAOK2,CRMP1,MICAL2,VCAN,RIMS3,MAML1,SPOCK2,GIT2,ATN1,ST8SIA3,FCF1,EFNB3,ELAVL3,EPHB1,FGFR1,FHL1,ANKFY1,GAD2,GALC,SIGLEC8,USP19,GLYR1,STON1,GUCY1A2,ATXN2L,KCND3,LAMA2,VWA5A,PACRG,MAN2A2,AFDN,MMP16,OPRL1,PGAM2,STRN3,RAB3A,CCDC40,ZNF821,TRA2B,SAMSN1,DMXL2,CRTC1,PCDHA6,TRPC3,ZIC3,PHTF2,SSPN" Drug 3344_UP Oxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "DPF1,NDRG2,LTBP4,FAM131A,ATP1A2,ATP6V0A1,GYG2,CA4,CACNG1,SLC16A4,RAB33A,TCEAL2,CSF1R,RIPOR2,RIMS3,DGKG,DBT,HIPK3,FRY,EFNB3,MBNL2,DMTN,ERCC2,ZNF589,FGF13,FHL1,OGA,GLYR1,GNAO1,GPM6A,MAOB,MGAT3,MMP17,MOBP,MSR1,NEUROD1,NF1,SNTG1,PDE1C,PDE3B,PLP1,STRN3,LRP12,TNPO2,PTPRH,RAB3IL1,TRIM68,SCG5,ASAP3,FNDC3A,COA1,KDM4B,ZNF423,AJAP1,ROBO3,DMXL2,TEX15,SPHK2" Drug 4743_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "FZD9,LTBP4,MRTFA,AMPH,APOC1,LGR5,ASCL1,MARK4,ATP1A2,ATP2B2,CA4,HIP1R,TMEM257,NDST3,CLCN4,VAX2,FAM149A,CSF1,SV2A,DRD1,ATN1,EFS,CEND1,ZNF589,AGAP2,FYB1,GAB1,GAD1,GAP43,RUNDC3A,GPD1,GSN,SOX21,KLF12,SETD4,CDK18,PPARA,PTHLH,PTPRB,RASGRF1,TCP11L1,EMID1,SCN2B,SCN8A,FAM214B,KANSL3,PKNOX2,SNCA,ATP10B,EPB41L3,ST5,MAPK8IP3,TRIM2,AMACR,TRPC3,VIPR2,KCNK12,DNALI1" Drug 5610_UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-07 2.28E-02 1.40E-05 1.60E-04 58 194 "DPF1,ADORA3,LTBP4,APLP1,CFAP410,CAMK2B,CNTFR,IFFO1,CSF1,CTIF,EGR3,EPHB1,ERCC2,KIAA1109,FGF13,FGFR3,ERGIC3,ERAP1,GNAO1,SPACA9,GRM1,FAM107A,GUCY1B1,KCNK2,KIFC3,MGAT3,CD200,MYO7A,NNAT,NPTX2,PDE4A,PFKFB2,POU6F1,PPP1R1A,LRRN3,MAPK7,MAPK10,PTPRD,RGS12,KCNIP1,SCN8A,ZNF821,FRMPD1,PKNOX2,SLC6A9,KIF13A,INKA2,ABCC8,POPDC3,WSCD1,ZEB1,CRTC1,R3HDM1,TRO,TTPA,OSBP2,XRCC4,SLC30A3" Drug ctd:C031180 chrysene CTD 4.76E-07 2.33E-02 1.43E-05 1.63E-04 193 880 "CLK4,SYS1,ADD3,ERMN,SPARCL1,ANK3,LCORL,PPFIA3,CPNE5,CDC14B,PDXK,ARNTL,ASPH,EIF4G3,ATP2A2,ATP6V0A1,BCHE,C5,CACNG1,THSD7A,CAPN3,USP2,CDC42,DNAJB5,MAP4K4,AKAP7,ABI3BP,RBM39,AKAP12,GDA,TENM4,PLCH2,RASGEF1C,GREB1,DCAF4,MYADM,FGFR1OP2,PHF19,PHYHIP,DCC,YTHDC1,ELMSAN1,MED24,NR1D2,DNM2,DMTF1,FAM57B,ARRDC4,ABCC5,EDNRB,SYT15,KLHL5,PHF20L1,KMT5B,EIF4G1,SRPK3,BSCL2,EML1,PAN3,EIF1,HSD17B14,EPB41,EFS,RTN3,F5,REEP2,FAM198B,FGFR3,POLK,ZMYND15,TACC2,SORBS1,TPK1,STAU2,PNMA2,OGA,GABRA3,CPLX2,PCDH17,LYVE1,GJB1,SPIN1,HTATSF1,PSRC1,CCDC184,GRB10,DIDO1,PLCD4,SERP2,PTPN5,MFSD2A,FAM107A,SLC2A6,ATG4C,RASSF8,NXPH3,HLF,HMGB1,CPT1C,CELF5,ICA1,ITGA7,ASPRV1,MAT2A,MDM4,MEF2C,KITLG,CD200,BLOC1S2,MSR1,NRBP2,THYN1,DDX25,MYBPC1,SFR1,NRCAM,P2RX7,ZDHHC22,PAH,PBX1,PDE4A,PFKFB3,CDK14,ABCB1,KCTD15,PLCD1,PMP22,CEP41,PKIA,LAMA1,MTMR10,PTPRB,PTPRG,PTPRZ1,TUG1,RGS12,TTLL7,CCDC82,ROBO1,MEG3,HUNK,RYR1,NCBP3,SMPD3,SELL,SH3BGR,SHC4,MAGI3,DZIP1,ZNF365,RUFY2,SLC8A1,ARHGEF40,EFHD1,SCN3B,SOX2,SPP1,ZNF423,TAB2,CLSTN2,INKA2,SEPT3,NSFL1C,SYNE2,PLCB1,COBL,ANKRD12,MLST8,EHBP1,TCF7L2,PCDHGA9,NSD1,PCDHAC2,GPRIN3,SLC35G2,AHCYL2,DICER1,ZMAT3,RASD2,ZNF346,ZMYND8,CA14,LRTM2,TMEFF2,SLC26A10,REEP1,RGS7BP,FAM13C,TTC7A,NHSL1,SSPN,AAAS,CPNE4" Drug CID000002303 Bay K 8644 Stitch 5.03E-07 2.46E-02 1.48E-05 1.68E-04 48 150 "ADCY5,ADCY6,ADCY8,AGT,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,RGN,LRBA,CACNA2D2,CHRM1,DMPK,EDN1,EDN3,CACNG7,CACNG3,CACNG2,ATP2C1,BVES,MAP4K5,KCNA4,NF1,NPY,NPPA,PIK3CD,PKD1,PRKACB,PRKCB,PRKCG,QDPR,KCNIP2,RYR1,RYR3,SST,TPCN2,TRH" Drug 7297_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "CFLAR,CHM,NRXN3,DNAJB5,AKAP5,IFFO1,CREB5,VCAN,CTNND2,CYBB,SPOCK2,G3BP2,RABGAP1L,DTNA,EDN1,FRY,CELSR3,EFEMP1,PRELID3A,CSPG5,GAD1,DISC1,ZNF276,GLRB,SPACA9,PTPRT,BACH2,HLF,HSD17B1,IL6ST,DIPK1A,KPNA5,SCAMP5,NOVA2,SERPINI1,MAPK3,SYTL2,PEX5,RAD52,RALGDS,FAT4,KCTD17,PAQR6,SCN8A,SH3BP2,LIMCH1,TMCC1,SOX2,SPP1,SS18,EXOC7,AP4E1,SLC44A1,TK2,LAT2,XRCC4,PRDM2,PARP6,SEMA3B" Drug 6462_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "KCNAB2,PDE8B,ASPH,RGS11,CFLAR,ARHGEF7,KALRN,CD86,CBFA2T2,KIAA1549L,WHRN,SLC4A7,TENM4,SPOCK2,HS3ST2,FAM13A,LRRC23,TUBB4A,DKK3,GABRA2,HBS1L,ERAP1,GRM1,HPCA,IL11RA,KCNJ5,KCNMA1,KIF5A,LAMA2,MMP16,MOBP,MSI1,BCO1,OPCML,SLC25A23,PLTP,LRP12,PRKAR1B,MAPK10,SAMD9,RGS12,ASAP3,SLA,SLC1A2,SLC8A2,COA1,SNAP25,KIF13A,ZCCHC24,KIF21B,HECW1,PEG10,AJAP1,PCDHA5,AP4E1,VAV2,VSNL1,NT5M,EPM2A" Drug 5458_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADD2,ADORA1,PLA2G6,BIN1,AMT,OGT,ANK1,APC,GAS7,PPP4R4,ALDH7A1,RGS11,CFLAR,CACNA1I,CACNA1D,INA,CDH18,CACNA2D2,ADGRG1,CHM,ARHGAP24,SPOCK3,SRGAP3,DMPK,SIDT2,C3orf18,CORO2B,KIAA1109,PRELID3A,ALDH1L1,RUNDC3A,GRB10,RAPGEF1,KHK,MAOB,MYO7A,PCDHGC3,CDK14,DUSP26,PACSIN1,TNPO2,LRRN3,PRKAR1B,GRAMD1C,VPS13C,PTCH1,PTX3,RAB3A,RAD52,ZMAT4,RGS7,SLC11A1,ATP10B,CLSTN2,TNS2,PCDHA5,UCHL1,DNALI1,KCNAB1" Drug 3754_UP Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "DPF1,AP2A2,KIAA1324,PLA2G6,GAS7,ARRB1,DDX3Y,FUBP1,CACNA1B,CAMK2B,CD86,CBFA2T2,CDO1,CHI3L2,SLC24A2,LRIG1,CNTNAP2,FRMPD4,ELMO1,SV2B,SRGAP3,ARNT2,ATN1,ING4,MRNIP,NCALD,FABP7,FGF1,OLFM1,SEMA4D,FYB1,GAB1,GALC,RUNDC3A,RND1,GNAL,GRIA4,SPACA9,GSTM5,IL1RAPL1,SOX21,IL6R,KCNH2,KCNN1,MEF2C,NPTX1,GPR85,PLP1,PTPRO,TRIM46,SUPT20H,IZUMO4,VAMP1,SLC44A1,TPM2,PDIA2,LAT2,ZNF154,EVI5" Drug 3872_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADORA1,AMH,AMPD3,APBA2,BRINP2,CHRD,CACNA1I,LDLRAD4,CACNA1A,CAMK2B,CHRNB2,TAOK2,WHRN,NCOR1,GREB1,SEC14L5,RIMS3,RUSC2,TMCC2,DYRK1A,EDNRA,TUBB4A,DLC1,KIAA1109,GDF9,GFER,GRIK5,GRM3,HLF,HTR2A,TJAP1,ITIH2,KCNJ3,KCNN1,MIA2,CNOT4,PCBP3,PFKFB2,LRP12,PTN,RGS12,RPS6KA2,SATB1,SLC2A5,SLC11A1,SLCO1A2,NPAS3,SSTR1,AJAP1,ABCC8,ARC,TBCEL,OBSL1,TNS1,TTPA,HIRA,LAT2,SLC30A4,SLC17A7" Drug 5754_UP Cromolyn disodium salt [15826-37-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "TRMT9B,APBB1,APC,EPB41L5,MARK4,DDX3Y,KIF1A,CAMK2B,USP2,AATK,RIMS3,DBT,DCT,SV2A,EXOG,EDNRA,CELSR3,PLXNC1,ING4,KIAA1109,FGF12,FGFR1,FOXG1,C1orf61,GAB1,GAP43,GATM,ALDH1L1,PRUNE2,LILRA2,GRM1,PADI2,ELOVL5,KIF5C,MMP16,NDUFA5,OPCML,PALM,NECAB2,MAPK10,ZCWPW1,RGS10,MYH14,RAVER2,RXRA,DZIP1,SLC1A7,SLC9A5,SYT11,SEMA4A,MCF2L,SYNE1,CRTC1,ICAM5,R3HDM1,ZIC3,ZNF74,NT5M,SLC17A7" Drug 3338_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "NDRG2,KIAA1324,APOC1,PRX,PLA2G4C,CCDC181,ATP2A2,CFAP410,HAP1,RUNX1T1,ARHGEF2,KCNAB3,PDE4DIP,CNTNAP2,SPOCK2,DTNB,MBNL2,C3orf18,ERCC2,PIPOX,F5,DLC1,OLFM1,C1orf61,AFF2,KHDRBS3,NEU3,ALDH1L1,RND1,GLYR1,LPAR4,GRIK5,GRM3,NXPH3,TJAP1,IL6R,KCNMA1,BCO1,NEFM,PCBP3,OMG,SNTG1,PNMA3,LRP12,RAD52,RASGRF1,RFX2,KCNIP2,SLC30A10,SLC1A7,SLC6A7,COA1,SMARCD3,ATP10B,INKA2,VAMP1,PCDHGA1,TEX15,SLC17A7" Drug 3097_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "SYN3,ANK2,FGD2,SEMA4G,PLA2G4C,DNAH17,ASPH,KSR1,CDK5R1,THSD7A,CD38,CHN2,TAOK2,ZFYVE9,NMT2,STOML1,DNAJB5,RAB26,FAM149A,CREM,AATK,RIMS2,KIAA0513,DSCAM,ST8SIA3,SEZ6L2,SORBS3,ELAVL3,TNK2,C3orf18,CEND1,CAMSAP1,FHL1,GPR75,KCND3,KCNJ5,MGAT3,AFDN,MPP2,MX1,LYRM9,TREM2,PFKFB4,NLE1,RGS3,RGS10,ZNF821,CCDC92,SLC11A1,RBM34,ARHGAP26,EXOC7,DOCK9,THRA,TNS1,SPHK2,ZBTB16,MAP3K12,NT5M" Drug 1521_UP Cyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "SYN3,APOC1,CDC14B,DNAH17,MARK4,KIF1A,AZGP1,CFLAR,SYNJ2,CACNA1I,CCK,ARHGEF2,RCBTB2,NMT2,DNAJB5,CSF1,DCAF4,DOCK4,DNAJC6,DNAH9,EFNB3,HSD17B14,BAIAP2,DISC1,GFER,RUNDC3A,GLS,MSL3,TDRKH,NR3C1,SLC2A6,HRH3,IPO5,VWA5A,SMAD1,MOBP,NEUROD1,PCDH9,CDK18,MAPK7,PRPH,PTN,ZDHHC14,RASA3,CNKSR2,SLA,PEX26,SMTN,SLC11A1,FAIM2,ATP10B,INKA2,MAPK8IP3,ATP11A,DMXL2,TRIM2,NPL,TPM2,WBP2" Drug 2470_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "TKTL1,ADORA1,PLA2G6,BIN1,DDO,ARHGDIG,KIF1A,PROM1,BMP7,CDK5R1,CACNA1G,CFAP410,HAP1,CBFA2T2,SRSF11,TAOK2,CLCN4,SULT4A1,RAB26,DCAF4,C2CD2L,SEZ6L2,HEYL,RASGRP2,STX2,APC2,HPCAL4,GPR153,GFER,PCDH17,GPM6A,GPR22,ADAMTS13,GRIK5,KLF12,IL6ST,MAP4,TAGLN3,ZNF862,NEFM,NPPA,OMG,PDGFRA,PMP22,CDIP1,MAPK8,RIPOR1,SH3GL2,SLN,DOP1A,TNIK,TACR1,ACSL6,TNS2,TIAM1,TMOD1,TRPC3,LMF1,PLSCR4" Drug 3632_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "PLA2G6,BEGAIN,PDE8B,SLC4A4,ALDH7A1,ARHGEF7,SGCE,LDLRAD4,CA4,HAP1,SLC16A4,NEURL1,CLGN,LHX2,FADS2,VAX2,AKAP5,PDE4DIP,SDC3,MFAP3L,C2CD2L,ATN1,ING4,ZNF589,FGF13,FOXG1,C1orf61,FOXF2,SEMA4D,TDRKH,PCLO,RASSF8,ITIH2,MAPT,MATK,MPP2,NEK1,NPTX1,NPTX2,PFKFB2,SMOX,EPN1,PPP5C,TMEM104,RGS10,RGS12,KCTD17,MYH14,GSTCD,SH3BP2,SOX2,TSNAXIP1,EMC1,SPTB,KIAA1107,RPGRIP1L,SLC35G2,WIPF1,UBE3B" Drug 7348_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADORA2A,NME5,BIN1,APBB2,PPFIA3,ARHGDIG,ASPH,RASL11B,SLC2A11,SYNJ2,BAIAP3,BTRC,SOCS6,CLCN4,QKI,NCOR2,SIPA1L1,FAM169A,TBC1D5,RIMS3,PARD6A,RABGAP1L,DSCAM,DTNA,EGFR,PLXNC1,FER,CAMSAP1,HBS1L,RND1,POLL,GNG4,CNTRL,ATXN2L,KCNJ3,NUMA1,PALM,SMIM7,PPARA,PPP5C,GON4L,PTCH1,FAM120C,RIPOR1,TRAPPC13,SBF1,FBXO11,WDTC1,ZHX3,ARHGEF9,PLCB1,ARC,COBL,SMG6,AP4E1,TK2,DNAJC12,PRDM2,SSPN" Drug 3762_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "C1QTNF3,PKP4,AQP6,ATP1A2,CACNA1I,CACNA1D,INA,CDO1,JAM2,RAB33A,ERC2,RIPOR2,SRGAP3,ARNT2,DLG4,MRNIP,ELN,APC2,ZIC4,DLC1,FGF1,BAIAP2,FYB1,RND1,GRM1,PTPRT,KCNH2,MGAT3,ADAM22,MSR1,TAGLN3,MYO7A,NOS1,NTRK3,OMG,PDE2A,PDE4A,PLP1,SPATA6,POU3F4,CEP41,MASP1,PTPRO,NKAIN1,RET,RNASEL,DGLUCY,ZNF821,STUM,SLC1A2,ZNF423,ZC3H13,MAPK8IP3,ACSBG1,SYT11,VAMP1,PLCB1,PIK3R5,FLRT2" Drug 5471_UP Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADCY6,AGT,ASPH,ALDH4A1,ALDH7A1,RCBTB2,SULT4A1,FHL5,CNTN1,CNTNAP2,JAKMIP2,HP1BP3,SGK2,FGFR1,CAMSAP1,FYB1,GNAO1,GNAS,GRK4,GRM7,ICA1,KCNH2,KCNN2,LMO2,MDM4,MMP16,NUMA1,PRKAR1B,GON4L,ZSCAN32,RAB3A,SUGCT,SALL1,ZNF821,ABLIM3,SLC2A5,PKNOX2,ELMO2,BTBD7,LIMCH1,PDZD2,WDTC1,FCHO1,SYN2,SYT5,TACR1,RPGRIP1L,PCDHGA10,CRTC1,TRPC1,FLRT1,VAV2,MICAL1,LMF1,SPHK2,MAP3K12,STMN4,HRASLS,JPH3" Drug 4637_DN Perphenazine [58-39-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "C1QTNF1,TRMT9B,AMH,SEMA4G,PDE8B,ASTN1,ATP2B2,ADGRB2,CFAP410,CAMK2G,TAOK2,NMT2,ABCG2,IQCK,CABP1,TBC1D5,KBTBD11,DTNB,FAM13A,ING4,SPEG,AFF2,DENND2A,GLYR1,HTATSF1,GNAS,GPR17,LPAR4,HNMT,ICA1,LIG4,MX1,NDUFA5,NPR2,NUMA1,PAK3,GRAMD1C,PROX1,CNTLN,PTN,PTPRB,ZSCAN2,ATG16L1,FRMPD1,ASAP3,SLC20A2,RBM34,SPTAN1,SS18,KAZN,ADGRL3,ARHGEF12,CRTC1,TMPO,RIMBP2,CABIN1,TNS1,MPPE1,FAM13C" Drug 3860_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADRA1D,AMH,AMPD3,BIN1,CDC42BPA,APP,ARRB1,DNAH17,C5,BAIAP3,CALB2,CAMK2G,CBFA2T2,CRLF1,ARHGEF4,RIMS2,DMPK,DUSP9,EPB41L1,NCALD,ZNF589,FGF12,FGFR1,FOXG1,PDLIM5,FAM49B,SRCAP,GFER,GLS,GRM8,RASSF8,ELOVL5,ITPKB,NPPA,NPTX1,RETREG1,PLEC,MINDY2,SNRK,RIPOR1,RAD52,ENOX1,ZDHHC14,TRIM68,RGS10,EMID1,SYNDIG1,SH3BP2,BTBD7,SPTAN1,TROVE2,RGL1,CHST8,TMOD1,TNS1,MICAL1,LAT2,KCNK12,SSPN" Drug 2320_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "RALGAPA1,ADORA2A,SPARCL1,ALK,CDC42BPA,CDK13,RASL11B,ADGRB1,CFLAR,MTMR3,GYG2,BAIAP3,CFAP410,CACNA1A,CDO1,CHRNB2,TAOK2,NCOR2,VCAN,SDC3,CYBB,SPOCK2,TMCC2,DTNA,FGFR1,PDLIM5,B3GAT1,DISC1,SRCAP,GLS,GPR37,ITIH2,KCND3,KCNJ5,KPNA5,MDFI,MOBP,CD200,BCO1,NPPA,PENK,PLCB2,POU3F4,CEP41,PTCH1,PTHLH,RAVER2,BCAN,SLC1A7,SLC9A5,SLC11A1,SLCO1A2,ZSWIM8,ATP10B,SSTR2,MAPK8IP3,KIAA0930,RALYL,OSBP2" Drug 6765_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ABHD6,AP2A2,BIN1,EPB41L5,ARRB1,ALDH7A1,CAMK2G,SCARB1,CACNA2D2,SLIT2,PICK1,CPS1,ARHGEF10,PDE4DIP,SDC3,ARHGEF4,RCAN1,NCALD,SCML2,CAMSAP1,FOXG1,SEMA4D,HBS1L,DISC1,SEPT9,GLS,GSN,ATXN2L,ELOVL5,KCNH2,MAP4,NNAT,SLC11A2,NUMA1,PDE3B,RETREG1,PPP2R2B,PEX5,FAM184A,MYH14,FOXRED2,ZNF821,COA1,LIMCH1,RBM34,WDTC1,ARHGAP26,SPTAN1,SPART,PHLDB1,VAMP1,PLCB1,KAZN,EXOC7,SLC44A1,HIRA,EMSY,HPS4,RNF170" Drug 5470_UP Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "RALGAPA1,ASIC1,NDRG2,AP2A2,PLA2G6,C1QTNF1,MRTFA,BIN1,SEMA7A,SEMA4G,PPP4R4,CFLAR,HAP1,CAMK2B,TAOK2,CLCN4,PICK1,WHRN,CSF1R,GPRASP1,C2CD2L,LRRC23,PDLIM5,ERAP1,SRCAP,RUNDC3A,GPD2,LILRA2,CNTRL,KLF12,HNMT,IL6ST,KCNN2,KIF5A,MYO7A,PIK3CD,FAM120C,KLHDC8A,NEK11,FRMPD1,CNKSR2,RPH3A,SLC1A7,KIF21B,ATP10B,ST5,SEMA4A,MCF2L,SZT2,PSD3,CHST8,TK2,TRIO,VIPR2,NSD2,ETNPPL,SPHK2,GDPD5,NUP214" Drug 5201_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ASPHD1,SRPX,BIN1,APBB2,APC,ASPH,BCL2L2,LDLRAD4,CACNG1,CBFA2T2,ARHGAP33,CHN2,WHRN,GREB1,SPOCK2,RUSC2,KBTBD11,SLC12A6,DRD1,DUSP9,EDNRA,EFNB3,FAM198B,DLC1,OLFM1,FGF12,SRCAP,RUNDC3A,GNG3,GRIK5,IRF8,KCNJ3,KCNN1,MID1,MPP2,ZNF862,NEFM,NF1,SERPINE2,PIK3CD,CDIP1,PPP5C,TMEM231,C1orf54,ZNF493,GSTCD,RPS6KA2,SYNDIG1,WDTC1,DOK5,PLCB1,TCF7,ZEB1,TRIM2,AHCYL2,RUNDC3B,SLC30A3,NT5M,TIGD6" Drug 3216_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "KIDINS220,PRX,PTCH2,SLC4A4,ALDH7A1,BTRC,HAP1,CAMK2G,RUNX1T1,MTMR7,CBFA2T2,NRG2,CNTNAP2,RIMS2,NOS1AP,CYBB,CTIF,DCT,ST8SIA3,HIPK3,ZNF589,OLFM1,FGF12,IQCG,DCTN2,SORBS1,DISC1,RUNDC3A,GNAL,GNG3,GRM1,ITPKB,MIA2,AFDN,MX1,ZNF862,NPPA,NPTX1,OPCML,GPR85,MAPK7,ELOVL2,ACSM5,RNASE1,CCDC102B,RPS6KA2,ST6GAL1,ANKRD6,EPN2,LIMS2,ZNF334,BEX1,MAPK8IP3,SYNE1,AP4E1,HIRA,LAT2,KCNK12,PRDM2" Drug 5635_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "DPF1,ACTN1,AMPD3,APAF1,MARK4,NRP2,KSR1,ARHGEF1,NEURL1,CACNA2D2,ASIC3,RAB33A,CNTFR,WHRN,CPS1,CRMP1,CNTNAP2,DTNA,DTNB,TOM1,EFNB3,EGR3,ZNF589,FHL1,HPCAL4,C1orf61,GABRA5,PCLO,TJAP1,KCND3,KCNK2,MEF2C,SLCO1C1,NPTX2,CDK18,PENK,PFKFB2,SERPINI1,PLCD1,POU3F4,CNTLN,ZSCAN2,CCDC40,C1orf54,ZFHX4,SYNDIG1,SEMA6D,FAM214B,LIMCH1,TNIK,KIF21B,HECW1,KIAA1107,WSCD1,DICER1,UBE3A,FLRT2,LAT2,KCNAB1" Drug 6654_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "RALGAPA1,ASIC1,NDRG2,BEGAIN,ANK2,CDC14B,ASCL1,CCDC181,CFLAR,KSR1,BMPR1B,BAIAP3,KALRN,HIP1R,NRXN2,DNAJB5,IFFO1,NCOR2,PLCH2,PDE4DIP,CNTNAP2,TOX,BRINP1,ARMCX2,HS3ST2,DTNB,EDN3,ANKMY1,EZH1,OLFM1,OGA,DKK3,GAB1,SRCAP,TDRKH,HPSE2,MOBP,ADAM22,OPRL1,PDE4B,PDGFRA,ENPP2,RETREG1,SPATA6,PRPH,DCHS2,SCN2A,RASA3,HKDC1,SNCA,SPP1,CAMTA2,VAMP1,SEMA4A,ICAM5,SEZ6L,KCNAB1,MVB12B,JPH3" Drug 454_UP cobalt(II) chloride hexahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "PLA2G6,ALCAM,AMPD3,GAS7,PPFIA3,ARSF,ASCL1,PDE8B,SLC2A11,ATP6V0A1,CFLAR,KALRN,AP4M1,ARHGAP33,FOXN3,CHI3L2,CHRNB2,SLIT2,TMEM59L,CNTFR,CDC42BPB,CRYM,AATK,PPP6R2,ECE2,ATN1,MBNL2,MRNIP,ELN,PIPOX,RASL12,TUBB4A,IQCG,POMT1,NCKAP1,GJB1,ZNF276,PRUNE2,ADAMTS13,NXPH3,NCKAP1L,AFF1,FXYD7,NPPA,SETD4,CEP41,RNF220,TCP11L1,SEMA6D,ATXN2,ASAP3,AMBRA1,DOK5,CDK19,DMXL2,TCF7,THBS4,FLRT1,MARCH8" Drug 6076_UP Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "NR0B1,LTBP4,ALK,BIN1,ANK1,AQP4,RGS9,LDLRAD4,HAP1,RUNX1T1,CLDN10,HAPLN1,NCOR2,SNCAIP,SEC14L5,SNPH,SPOCK2,CTIF,ATN1,ZNF391,REEP2,C1orf61,OGA,GABRA5,SRCAP,GLRB,GNAO1,PRUNE2,ADAMTS13,GSTM5,HRH3,KLF12,HPSE2,KCNH2,KCNMA1,MAP4,MMP17,TAGLN3,CNOT4,P2RY1,TREM2,RETREG1,FXYD1,PURG,PPP5C,PRKCB,PSD,RASGRF1,RGS12,RPH3A,SLC2A5,PKNOX2,BEX1,TCF4,PSD3,SLC44A1,SEZ6L,UBE3A,CA10" Drug 366_DN Gleevec; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "AK2,C1QTNF3,BIN1,AMT,ANK2,SLC4A4,MTMR3,CALB1,NEURL1,DLGAP1,CLCN4,NRXN1,CPS1,ARHGEF10,GREB1,CTIF,KLHL3,RCAN1,DTNA,EGFR,MBNL2,SORBS3,STX2,FABP7,ZIC4,RASL10A,GAB1,GAD2,LUZP2,GRM7,SOX21,VSIG4,HAPLN2,KCNA1,AFF1,ADAM22,NPR2,NTRK3,PDE4D,CAMKV,STRN3,SDK2,PTPRD,GAL3ST4,RNASEL,ITSN1,SLC8A1,KBTBD4,IGSF9B,SNAP25,EMC1,ZC3H13,NPAS3,NXT2,AJAP1,TBL1X,SEZ6L,TPM1,MARCH8" Drug 4728_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ASIC1,APBA2,CACNA1I,HAP1,CNOT8,RAB33A,PICK1,AATK,CSF1,CTIF,SPOCK3,TRAPPC9,EDN1,ELAVL3,RASGRP2,ERCC2,IGSF6,FOXG1,NSG1,GABRA2,GAD1,ALDH1L1,SRCAP,RUNDC3A,RND1,GNAS,GPER1,GRIK2,SPACA9,ICA1,KCNH2,KHK,KIF5A,MAP4,AFDN,LYRM9,NELL2,OMG,CDK18,PENK,PPARA,PRODH,PTHLH,RAD52,C1orf54,TCP11L1,EMID1,SH3GL3,NTNG1,SLC14A1,ARHGAP26,ATP10B,INKA2,MAPK8IP3,CRTC1,TMOD1,FLRT2,XRCC4,ITM2C" Drug 3535_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "KIDINS220,AK2,PLA2G6,CDC14B,BTRC,CACNG1,SOCS6,SULT4A1,SH2B1,PDE4DIP,HDAC4,RUSC2,TOM1,TSPAN5,EFNA3,EIF4G2,HSD17B14,EN2,LRRC23,STX2,ACSL4,FHL1,FLNC,DPYSL4,GAB1,DISC1,GRIK5,NR3C1,GRM1,INPP1,KCNH2,MEIS1,NNAT,OGG1,PIK3CD,PPARA,MAPK8,TMEM104,PEX5,RAD52,ZCWPW1,RGS3,SEMA6D,SLC15A2,WDTC1,ZHX3,UNC5B,THSD1,PHLDB1,RPGRIP1L,ZNF34,SLC44A1,TRIO,VLDLR,WIPF1,UBE3B,SMIM8,PHTF2,RNF170" Drug 3421_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ACTN2,ARID1A,NME5,LTBP4,DOC2A,PPFIA3,PDE8B,ASPH,ALDH4A1,ST3GAL5,BTRC,CAMK2G,HIP1R,SCARB1,CDH8,TAOK2,LHX2,TPP1,HOMER3,AKAP7,ABI3BP,NECTIN3,CSF1,GREB1,MAML1,RUSC2,EDNRA,DLC1,ZNF589,FGF12,FGFR1,GABRA2,HBS1L,DISC1,PTGDR2,LSS,MAOB,MBD1,MID1,MSR1,NDUFA5,PDE3B,SLC25A23,PTPRE,GAL3ST4,RGS3,RGS10,PPP1R9A,SYBU,WDTC1,CLSTN2,INKA2,TGFBR3,THRA,TIAM1,TMOD1,CDK20,VGF,REEP1" Drug 4354_UP Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "FZD9,ADORA1,CDC14B,CDK13,ASPH,DDX3Y,ADAM23,NRP2,SCAPER,CACNA1G,RUNX1T1,CABP1,MYRIP,VCAN,HDAC9,SPOCK2,C3orf18,EN2,EFS,FABP7,SORBS1,PDLIM5,FYB1,LPAR4,ATXN2L,SCRG1,IRF8,SHISAL1,KCND3,KCNH2,KCNN1,TAGLN3,PAH,PCDH9,PIK3CD,CEP41,MAPK7,MAPK8,SNRK,BAALC,RPS6KA2,RPS20,SLC30A10,MRAS,SLA,SLC1A7,TNIK,ZSWIM8,ZNF423,ZC3H13,ACSBG1,SYT11,SYT5,SYNE1,R3HDM1,TRO,UCHL1,XRCC4,JPH3" Drug 3202_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "AMPD3,APLP1,CDK13,ATP2B2,ADAM23,BACH1,PROM1,KSR1,BAIAP3,ARHGAP33,B4GALT6,SLC22A6,CNR1,CPS1,ATRNL1,TMCC2,DTNA,DUSP9,PLXNC1,ACSL4,KIAA1109,NSG1,ATP8A2,TDRKH,NR3C1,GRM8,IGF1,JAK2,KCNC1,KCNN1,MARK1,MITF,MOBP,MYO7A,FXYD6,NCAM1,NPPA,NTRK3,CLDN11,PAX6,PFKFB2,PPP5C,ZFHX4,TCP11L1,ZFP2,RPH3A,FAM214B,SLC6A9,SLC11A1,SHANK2,SPTB,DDN,SSTR2,ARC,SYT5,ROBO3,OBSL1,PIK3R5,VGF" Drug CID000000836 "3,4-dihydroxyphenylalanine" Stitch 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "KDM5D,ADCY5,ADCY6,ADCY8,ADORA2A,API5,ATP1A3,SGCE,CBS,SOCS6,CNR1,BOC,DCT,DRD1,EEF1A2,TUBD1,TUBB3,TUBB4A,PPP1R1B,SCARA3,GAD1,GAD2,TUBA8,LOXL3,TUBA1C,GRIK1,GRIN2C,GRIN2D,GRM5,IGF1,IGFBP1,TUBB2B,MAOB,MAPT,MAT2A,MT3,PAH,PDYN,PENK,FXYD1,PTN,QDPR,ZFHX4,LRRK2,SLC1A2,SNCA,SST,TAC3,MLST8,ATP13A2,TMPO,TRH,TUBB2A,TUBB1,UCHL1,PORCN,DPYSL5,TUBA1A,NELFE" Drug 2744_DN Dipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "MRTFA,APC,FAM131A,APOC1,PPFIA3,ARHGDIG,ATM,SLC4A4,BCL7A,SCAPER,GYG2,SCARB1,B4GALT6,ZFYVE9,FAM189A2,SIPA1L1,MFAP3L,PARD6A,RABGAP1L,HIPK3,EFNB3,SORBS3,F3,KAT8,BAIAP2,FAM49B,OGA,SEPT9,ALDH1L1,GLYR1,MSL3,ARHGAP19,KCNH2,MMP16,ADAM22,NPR2,NRGN,PRPH,GON4L,ZCWPW1,RGS10,RIC8B,FOXRED2,SH3BP2,FNDC3A,EPN2,BTBD7,ZHX3,ELOVL4,STX1A,PLCB1,ATP11A,EXOC7,PCDHA6,TMOD1,RUNDC3B,HIRA,KCNK12,PHTF2" Drug 5393_UP Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "AGT,SEMA7A,CDC14B,ADGRB3,BTRC,TPP1,SULT4A1,SLC4A7,EDRF1,CTIF,HEPH,DMPK,EDNRB,PLEKHO1,VPS13B,COQ7,GLYR1,RAB30,GNAO1,GNAS,PCLO,CNTRL,NR3C1,GRM3,GRM7,IL11RA,LMO2,MYO7A,NEUROD1,NFYA,NTRK2,PDE3B,LRP12,C19orf57,PPP5C,ZFHX4,TCP11L1,ZNF821,HKDC1,BCAN,ARHGEF40,SLN,SMARCD3,MAPKBP1,ARHGAP26,IQSEC2,RBM26,RGL1,ARC,KIAA1107,ZNF34,UCHL1,FLRT2,ZIC3,SYNC,NT5M,ST7,TIGD6,SENP7" Drug 4957_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "BIN1,ALDH7A1,SCAPER,CACNA1I,CACNB2,CACNG1,CNTN1,CRMP1,NCOR2,VCAN,DAPK1,NTM,TMCC2,DTNB,EGFR,TNK2,ELAVL4,ELN,ERCC2,EFS,PIPOX,ST3GAL6,KIAA1109,GPR153,B3GAT1,GAD1,GPM6B,ATF7,LPAR4,GSTM5,SOX21,KCND3,VWA5A,MSR1,NEUROD1,NOVA2,RETREG1,PRKAR1B,FAT4,SEMA6D,ZFP2,FAM214B,CCDC88A,SLCO1A2,SNCA,KIF21B,PHLDB1,PLCB1,SMG6,CRTC1,CHST8,HEY2,TRPC1,VGF,LAT2,PRDM2,ADAMTS9,HRASLS,DPF3" Drug 5687_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "SYT13,DDO,CDC14B,SPTBN4,ASCL1,N4BP2L1,ADAM23,NRP2,KSR1,CALB2,CD86,CHRNA4,SLC24A2,CSF1,SRGAP3,DOCK2,DSCAM,EGR3,COQ7,RASGRP2,KCNMB2,CORO2B,FGFR1,AGAP2,MYOZ2,SRCAP,CSDC2,GLS,GPM6B,TDRKH,GSN,IRAK3,INPP5B,MOBP,MYT1,PALM,PDE4D,PACSIN1,VPS13C,TTLL7,KCNIP2,KCNIP1,FRMPD1,ASAP3,DOCK10,FNDC3A,SLCO1A2,LIMCH1,SOX11,ZSWIM8,HECW1,SYT5,TRIM2,TEK,CHST5,UBE3A,LAMP5,SLC30A3,SEMA3B" Drug 2781_DN Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "C1QTNF3,DOC2A,APC,APP,ASPH,ALDH4A1,FUBP1,WASF1,CBFA2T2,CHM,VAX2,CREM,PDE4DIP,MAML1,DSCAM,HIPK3,EFNB3,NCALD,RRAGB,F3,KIAA1109,PRELID3A,GLYR1,RAB30,MSL3,HNMT,KCNH2,LSS,MEIS1,MMP16,ZNF862,NACA,NF1,PDE3B,RETREG1,MBOAT7,WDR25,ZSCAN2,RAD52,RGS10,SH3BP2,SYBU,SMTN,SLC22A4,RBM34,WDTC1,ZCCHC24,TSPYL2,INKA2,SUPT5H,AP4E1,TMOD1,KAT6B,RUNDC3B,ZKSCAN5,ZBTB14,MAP3K12,DNALI1,SENP7" Drug 3523_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADCY6,FZD9,ADGRF5,ALK,AQP4,CDK13,ATP2B2,AZGP1,SYNJ1,ARHGAP33,TENM4,CSF1R,MICAL2,SDC3,DRD1,ATP8A1,ZNF589,FOXG1,SORBS1,NEU3,RND1,RAB30,GNG4,GPR22,RAPGEF1,GRM7,WIF1,PTGDR2,IRF8,TJAP1,ITIH2,KCNJ5,LAMA2,MDFI,CD200,PDE3B,PENK,PFKFB2,STRN3,RELN,GON4L,PTPRH,RAB3A,RAB3IL1,SCN2B,SCN7A,SH3BP2,ST6GAL1,PKNOX2,SLCO1A2,PDZD2,SOX2,MAPK8IP3,KIAA1107,CUX2,DOCK9,DNAH7,ICAM5,KCNAB1" Drug 3759_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "TTYH1,NDRG2,ADCY6,AP2A2,AQP4,N4BP2L1,KALRN,BRSK2,NRXN1,NRG2,SUSD5,DAPK1,ARNT2,DLG4,ING4,OLIG2,ETV1,OGA,GAB1,GABRA2,MYOZ2,GNG4,GRIN1,GRM2,GRM3,ICA1,IRF8,KCNA4,KCND3,KCNQ3,MAN2A2,MBP,MEF2C,NPY,NUMA1,PDE2A,PFKFB4,CAMKV,EPN1,PACSIN1,LRRN3,PTPRH,RASGRF1,STK32B,SYNDIG1,PAQR6,SALL1,STUM,CNKSR2,SLC2A5,RIMS1,DDN,INKA2,MAPK8IP3,VAMP1,RIMBP2,SEZ6L,RPRM,SLC17A7" Drug 3730_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADD2,NME5,FAM135A,AMPD3,APBB1,EPB41L5,PPP4R4,RASL11B,CADM3,ADAM23,TAOK2,SLC24A2,SH2B1,MYEF2,DTNA,ING4,KAT8,KIAA1109,BAIAP2,C1orf61,GABRA2,GAD2,GPD1,GPD2,ATF7,GPR19,GPER1,GRM1,GRM3,GSTM5,SOX21,IRF8,KCNH2,ADAM22,NPTX1,PALM,SPATA6,PPARA,PKN2,PTAFR,PTN,RFX2,RPS20,KCNIP1,RYR1,RASA3,FNDC3A,RPH3A,SLC11A1,RBM34,INKA2,TACR1,TRIM2,CRTC1,SLC44A1,PIK3R5,SLC30A4,KCNAB1,KAT6A" Drug 3013_UP Propantheline bromide [50-34-0]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ABAT,ADCY8,PLA2G6,ANK2,PDE8B,ASPH,CHN2,DNAJB5,COL9A3,NCOR2,SIPA1L1,DLG4,TRAPPC9,DRD1,CNNM1,SRPK3,RASGRP2,EPHB1,FAM198B,GABRA1,GABRA3,ADAM28,PCLO,HPSE2,HPCA,HTR2A,SCIN,KCNH1,PACRG,MDFI,NTRK3,OXTR,PDGFRA,PPARA,SYTL2,PTHLH,FAM120C,RIPOR1,RGS4,ZFHX4,NEK11,RYR1,KIF16B,LIMS2,FAM214B,SLC11A1,ZSWIM8,PEG10,LHPP,PLCB1,SYT1,TBL1X,TNS1,SEZ6L,LILRA4,CDK20,TPM2,SPHK2,PMEPA1" Drug 7467_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "AP2A2,PLA2G6,ARRB1,MARK4,ALDH7A1,CFLAR,MTMR3,CAMK2G,KYAT1,NEURL1,SOCS6,FAM149A,RCHY1,SEC14L5,EXOG,EDIL3,PHF20L1,ELN,STX2,BAIAP2,C1orf61,GAD2,B4GALNT1,GAP43,ERAP1,RAB30,CACFD1,DHX35,TJAP1,MAP4,MDM4,NELL2,PCDH9,PFKFB2,PLCD1,EPN1,PLTP,PPP5C,PTAFR,ZSCAN32,GSTCD,PAQR6,ASAP3,BCAN,SLC11A1,CXXC4,CAND2,ZC3H13,SYT5,SEMA4A,TCF7L2,TMEM121,SLC44A1,BHLHB9,PARD3,SEZ6L,CDK20,ZKSCAN5,SEMA3B" Drug 5426_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "DPF1,ASIC1,C1QTNF3,BIN1,APLP1,APOC1,SGCE,BAIAP3,LDLRAD4,CACNA1A,CACNA1D,SYNGR3,ADGRG1,STOML1,CRMP1,VCAN,PPP1R16B,SEC14L5,ATN1,DUSP9,ING4,MTSS1L,ZNF391,ACSL4,DLC1,FOXG1,DCTN2,SEPT9,SRCAP,GFER,GLS,POLL,NR3C1,CELF3,VWA5A,MAPT,MGAT3,OMG,PDE1C,PURG,PRKCB,MAPK10,RAD52,SELL,ZCCHC24,ZHX3,ATP10B,ARC,TACR1,TBCEL,TIMP4,TK2,XRCC4,ZIC3,DNALI1,SCG2,ITM2C,PLSCR4,FAM13C" Drug 1605_UP Clopamide [636-54-4]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "NDRG2,PLA2G6,ALAD,CDK10,PDE8B,SLC4A4,CADM3,ADGRB1,ADGRB2,CA12,CACNA1A,CALB2,SPAG9,CHN2,CNTFR,CNTN1,TMCC2,TRAPPC9,SORBS3,TNK2,SRPK3,FCGRT,GAP43,ALDH1L1,SPACA9,CACFD1,PRDM5,NXPH3,LAMA2,MAP4,GIT1,NNAT,NOS1,NPPA,OMG,DUSP26,CAMKV,PACSIN1,POLG,GON4L,PTK2,PTN,PTPRN,ARHGEF10L,RNASE1,PLPPR3,RXRA,BCAN,LIMS2,SLC11A1,SNAP25,SPTB,SYN2,CRTC1,DNAH7,LILRA4,VGF,VIPR2,NUP214" Drug 3845_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ABHD6,ARID1A,AP2A2,NME5,MRTFA,AMH,CDC42BPA,APC,APP,CDK13,MARK4,GYG2,SGCE,C5,CALB2,CSF1,RIMS2,NOS1AP,ZNF804A,MFAP3L,DMPK,EDNRA,ELN,HSD17B14,ZNF589,FYN,SYT17,GFER,TDRKH,GPR19,STON1,GRIK5,SLC2A6,HNMT,INPP1,MIA2,MPP2,MYO7A,NPR2,RETREG1,SLC25A23,POLG,PRPH,SNRK,TMEM104,ZSCAN2,RAB3A,EPN2,FAM214B,SLC15A2,WDTC1,ARHGEF9,MCF2L,CRTC1,TNS1,PLPPR2,VIPR2,LMF1,KCNK12" Drug 2251_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "CDC42BPA,ANK1,AQP6,MARK4,BRINP2,SLC2A11,ADGRB3,NRP2,KSR1,GYG2,CACNA1D,CDH2,TAOK2,ZFYVE9,DNAJB5,CSF1R,SDC3,CTIF,DMPK,TRAPPC9,DRD1,ATN1,EDN3,PIPOX,ST3GAL6,KIAA1109,DCTN2,CSDC2,LYVE1,GLS,KLF12,TJAP1,KCNC1,KCNQ2,LMO1,MEF2C,PDE4A,CDIP1,LRP12,TNPO2,LRRN3,MAPK7,RELN,SAMD9,PTX3,RAB3IL1,CCDC40,RAD52,SLC2A5,BTBD7,OGDHL,MLC1,JMJD6,WSCD1,PSD3,PRDM2,NT5M,SLC17A7,SMIM8" Drug 6444_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADRA1D,KIDINS220,MRTFA,CDC42BPA,ARHGDIG,CDK13,CADM3,CACNA1G,CFAP410,NEURL1,CHRNB2,EPS15L1,CABP1,HAPLN1,ARHGEF10,DAPK1,DCT,KIAA0319,SRGAP3,ATN1,SIDT2,ST3GAL6,FHL1,DCTN2,GAD1,PTGDR2,HPSE2,KIT,MBD1,AFF1,MX1,MYH6,NF1,CNOT4,PLTP,LRP12,SAMD9,PTHLH,RGS4,KCTD17,RYR1,LRRTM4,SH3BP2,ST8SIA1,PPP4R3A,KANSL3,SNCA,FAIM2,EPB41L3,SYNE1,OBSL1,HIF3A,RIMBP2,TPM3,WIPF1,ZNF711,SLC30A3,EMSY,SCG2" Drug 4973_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ASIC1,ABHD6,APLP1,FAM131A,NRP2,GYG2,CACNA1I,BAIAP3,LDLRAD4,CLGN,SOCS6,LHX2,CLCN4,CNTFR,TCEAL2,CRY2,CSF1R,VCAN,EDRF1,RASSF2,DCT,ATN1,EDIL3,SGK2,FCF1,LRRC17,IGSF6,PTK2B,ZNF589,SCARA3,FOXF2,GPR153,FYB1,RUNDC3A,STON1,GPER1,PCLO,GSN,ICA1,TJAP1,KCNH2,KCNJ5,KPNA5,MAP2,NEUROD1,ENPP2,PLXNB1,PDZRN4,ATG16L1,TCP11L1,DOCK10,PKNOX2,SNCA,DOP1A,AJAP1,AP4E1,PIK3R5,SYNC,STMN4" Drug 5078_UP Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ANK1,AQP4,CCDC181,NRP2,BAIAP3,LDLRAD4,INA,CACNA2D2,CBARP,JAM2,IQCK,PDE4DIP,PPP1R16B,NOS1AP,TOX,BRINP1,COQ7,MTSS1L,F5,AFF2,ZNF44,HBS1L,GNG3,GPD1,GRIK1,GRIN1,ADAMTS8,KCNA2,KCNC1,KCNN1,VWA5A,LSS,MATK,AFDN,MOBP,NRCAM,PDE4B,ST8SIA5,PPP1R1A,PRKAR1B,RAD52,SLC6A15,EMID1,ZFP2,NLGN1,SLC6A1,SLC11A1,SNCA,FAIM2,DDN,VAMP1,PCDHGA10,TPM1,TRH,AMOT,XRCC4,PRDM2,SEMA3B,ST8SIA2" Drug 4979_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "AK2,EPB41L5,ATM,ATP6V0A1,CFLAR,BTRC,QKI,ENTPD4,PPP6R2,GIT2,C2CD2L,EXOG,GNE,DTNA,E2F5,EFNA3,CELSR3,COQ7,VPS26C,TPK1,PRELID3A,OGA,HBS1L,DIDO1,SLC2A6,HNMT,IL6ST,INPP5B,ITPKB,JAK2,LMO2,MAP4,ADAM22,NPTX1,PLCD1,PLEC,POLG,MINDY2,MAPK7,RALGDS,ZCWPW1,ATXN2,ABLIM3,UNC5B,SPTAN1,CAMTA2,ASTN2,WWC1,RPGRIP1L,PSD3,ARHGEF12,ZNF34,SLC44A1,KCTD2,KAT6B,TRIO,REEP1,WNK1,MVB12B" Drug 4584_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ASIC1,KCNAB2,APC,CDK10,ADGRB2,SYNJ2,CACNA1A,SYNGR3,TPP1,RAB26,CPS1,HAPLN1,AATK,RUSC2,SMG7,PARD6A,DMPK,MBNL2,ELAVL3,EPB41L1,F3,FYN,GAD1,GLI2,MAP4K5,ATXN2L,DHX35,MDFI,MIA2,NDUFA5,CNOT4,MAPK8,PROX1,CNNM2,SAMD9,CNTLN,PID1,RGS3,ZNF671,TCP11L1,ZNF821,SH3GL2,FUZ,FBXO11,ARHGEF40,CDK5RAP2,TROVE2,SAMSN1,NCDN,VAMP1,PLCB1,PDLIM2,KIAA1107,SYNE1,ARHGEF12,TNS2,CHST8,TNS1,UPF3A" Drug 3286_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "ADCY6,ADORA1,PLA2G6,MRTFA,SEMA7A,APBA2,APC,PDXK,ALDH4A1,ALDH7A1,CFLAR,SYNJ1,CBFA2T2,FOXN3,PICK1,CNTN1,CSF1R,SDC3,RIMS2,DCAF8,RIMS3,MAML1,SGSM2,DTNB,ELN,SPEG,ZNF589,C1orf61,AFF2,KHDRBS3,GRM8,ATXN2L,JAK2,KHK,LMO2,NOVA1,PLTP,MAPK7,GRAMD1C,C1orf54,RPS6KA2,ASAP3,SLC9A5,KIF13A,ZSWIM8,NCDN,FAM168A,KIAA1107,DMXL2,RPGRIP1L,OBSL1,CRTC1,R3HDM1,TNS1,PLPPR2,NDRG4,DNALI1,HPS4,WIPF2" Drug 4219_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.08E-07 2.49E-02 1.48E-05 1.68E-04 59 199 "SLC12A5,ASCL1,B3GALT2,N4BP2L1,AZGP1,KSR1,BMPR1B,LDLRAD4,CAMK2B,SLC16A4,NEURL1,ARHGEF2,DLGAP1,GPR37L1,CBARP,PLEKHB1,CLTB,FAM149A,COL9A3,CRYBB1,CSF1,CX3CR1,TOX,DMD,DYRK1A,EDN3,EPHB1,EFS,ZMYND10,GALR1,RUNDC3A,GLI2,GNAL,PTGDR2,HPSE2,HTR2A,HTR5A,IL6R,AFDN,MSR1,NF1,PCSK5,SEPT4,RASGRF1,SLC6A15,RGR,FRMPD1,SLA,CXXC4,CDK19,INKA2,PHF24,TEK,SPX,TLR4,R3HDM1,SEZ6L,KCNK12,WNK1" Drug 2378_UP Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.13E-07 2.51E-02 1.49E-05 1.70E-04 55 181 "ADD3,BRAP,BIN1,GAS7,APP,ARRB2,ST3GAL5,CACNA1I,CD86,CD38,REPS2,KCNAB3,RCBTB2,CHN2,TPP1,CREM,PPP1R16B,SEC14L5,DOCK4,HEYL,LPAR6,PIPOX,DLC1,TESK2,B3GAT1,PCSK1N,GNAO1,GRIK5,TAGLN3,ZNF862,NEK1,SLCO1C1,OLR1,PDE3B,PDE4B,ENPP2,PLEC,PILRA,POU3F4,PTAFR,PTPRB,GAL3ST4,SEC14L1,SH3BP2,LIMS2,ARHGEF40,ZSWIM8,ARHGEF9,PLCB1,PDLIM2,TBCEL,ZNF34,TK2,TRPS1,FLRT2" Drug CID000031304 picrotoxin Stitch 5.13E-07 2.51E-02 1.49E-05 1.70E-04 55 181 "ABAT,SLC12A5,BCS1L,BID,WASF1,CACNA1D,CACNB2,CASC2,CLCN3,CLCN4,DBI,DMPK,DRD1,EIF4G2,GPHN,ADGRV1,FDFT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MEST,PTCH1,GLDN,ANKRD6,SLC6A1,SLC6A11,SST,SYT1,MLST8,ZEB1,PORCN" Drug 3629_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.13E-07 2.52E-02 1.49E-05 1.70E-04 57 190 "NDRG2,KLRC4,APOC1,FGF17,CFAP410,CACNG1,USP2,CLCN4,CRYM,TENM4,CTIF,DCT,RUSC2,SRGAP3,TRAPPC9,DTNB,CDKL3,ETV1,PIPOX,CSPG5,HBS1L,DISC1,SRCAP,RND1,PTGDR2,ITGA7,KCND3,KCNH2,MAN2A2,ZNF862,NELL2,NNAT,NPY,OPRL1,PDGFRA,PLTP,PRKCB,RAD52,TTLL7,RYR1,ASAP3,SLC11A1,SHANK2,SLCO1A2,SOX10,HECW1,RBM26,ATP10B,SYN2,ATP11A,WSCD1,THBS4,HEY2,TMOD1,AMACR,TRPM2,TUB" Drug CID000004266 muscimol Stitch 5.60E-07 2.74E-02 1.61E-05 1.84E-04 43 129 "ABAT,ACHE,SLC12A5,CCK,SOCS6,CHRM1,DBI,DRD1,DTNA,EEF1A2,STX2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GFER,GLRB,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,NPY,OPRL1,PENK,GLDN,SLC6A1,SLC6A11,SLC12A2,SST,TAC1,MLST8,TIMP4,TRH,PORCN" Drug 2880_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "AMT,SEMA4G,ARHGDIG,SLC4A4,SYNJ2,ASIC3,PLAA,QKI,ABI3BP,ABCG1,PHF14,GREB1,NOS1AP,DCAF8,MFAP3L,HP1BP3,KBTBD11,SLC12A6,CNNM1,VPS13B,DMTN,F3,FGFR1,IQCG,PDLIM5,MALT1,RAB30,MSL3,GNG4,JAK2,MBD1,NF1,NPR2,NRGN,CCSER2,PLCD1,MBOAT7,PPP5C,MAPK8,CNNM2,RAB3A,RAD52,RGS12,WLS,CLIP1,SFPQ,ZFP30,SH3BP2,SOX3,CDK19,TROVE2,CAMTA2,CRTC1,CHST8,TMOD1,TMPO,PLPPR2,DNALI1" Drug 5240_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "NDRG2,TRMT9B,APAF1,APBB2,GAS7,KIF1A,BCL7A,CFLAR,CA4,ARHGEF2,ARHGAP33,FAM189A2,CRY2,SIPA1L1,SDC3,GREB1,DCAF8,CTIF,SLC12A6,EDN1,ING4,LRRC23,ZNF589,FER,FGF13,PCDH17,MSL3,STON1,RAPGEF1,GRM1,JAK2,KCNJ5,KIF5A,MBD1,MEF2C,ZNF862,NF1,MTRF1L,MAPK8,SAMD9,PTHLH,RAB3IL1,ZCWPW1,KHDRBS2,RGS12,SH3BP2,LIMCH1,KDM4B,ZCCHC24,KDM4C,ASTN2,WSCD1,PCDHA5,UCHL1,XRCC4,SCG2,ITM2C,FAM13C" Drug 5452_UP Procarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ADRA1B,FAM135A,BIN1,ANK1,APBA2,KCNAB2,APLP1,RGS20,SLC4A4,N4BP2L1,ST3GAL5,SCAPER,CACNG1,USP2,DLGAP2,CHRNB2,CLCN4,SULT4A1,CRMP1,DCAF4,RIMS3,HS3ST2,HIPK3,EFNB3,ING4,LRRC17,ERCC2,FOXG1,GATM,GRB10,NR3C1,KCNN1,KCNQ3,MMP17,NAP1L3,PDE4A,ENPP2,PLCB2,PLCD1,POU3F2,SAMD9,RAB3IL1,PID1,C1orf54,CCDC25,RPS6KA2,CNKSR2,FAM214B,RIMS1,WDTC1,PEG10,VAMP1,POPDC3,ZEB1,CRTC1,FAM155A,PLSCR4,DPF3" Drug 3642_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "KIAA1324,MRTFA,APOC1,MARK4,ATP1A3,ST3GAL5,GYG2,HIP1R,CHRNA4,CSF1,MAML1,CTIF,HS3ST2,SGK2,EFNB3,ELAVL4,C3orf18,FABP7,KIAA1109,CAMSAP1,FLT1,PDLIM5,GAD2,SRCAP,GRM7,GUCY1A2,MOBP,MSI1,ZNF862,NEUROD1,NUMA1,CDK18,PFKFB2,PLTP,PLXNB1,PNMA3,CEP41,MAPK8,PTH1R,TTLL7,RNASEL,SCN8A,STUM,SH3BP2,HECW1,ZBTB43,POGZ,ACSBG1,ATP11A,WSCD1,TCF7,SZT2,FAM189A1,TEX15,TPM2,UBE3A,LAT2,ZNF225" Drug 3376_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "NME5,BIN1,EPB41L5,APLP1,FAM131A,RGS20,MARK4,SCAPER,CACNB2,HAP1,USP2,CACNA2D2,STOML1,RIMS3,DTNA,HIPK3,EFNB3,SUGP2,FGFR1,SCARA3,SEMA4D,FAM49B,OGA,ALDH1L1,ZNF276,RND1,GSN,IL6ST,JAK2,KCNJ3,MBD1,MIA2,KITLG,NOS1,PALM,PCDH9,PDE4A,LRP12,PPP5C,GON4L,PTPRO,RAD52,ZFHX4,FBXW7,TCP11L1,FAM214B,PKNOX2,SIRT2,SLC15A2,ZCCHC24,TSPYL2,ST5,DMXL2,ZNF45,REEP1,PRDM2,DNALI1,SMIM8" Drug 3346_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "KIDINS220,NME5,CDC42BPA,LDLRAD4,CACNG1,CALB1,CAMK2B,ARHGEF2,FOXN3,SULT4A1,PICK1,AKAP7,NCOR2,CYBB,RUSC2,CNNM1,MBNL2,EGR3,ERCC2,F3,FAM198B,SCML2,FHL1,FYN,GAB1,SRCAP,GLS,GPER1,ADAMTS13,GSTM5,ICA1,IL6R,INPP5B,MAPT,MGAT3,MX1,MYH6,NOVA2,PCBP3,TREM2,LRP12,PEX5,KHDRBS2,MYH14,RPS6KA2,DZIP1,ZNF365,KANSL3,PKNOX2,SLC6A9,CCDC88A,SLC20A2,KDM4B,ABCC8,WSCD1,DMXL2,TMOD1,TTPA" Drug 4092_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "C1QTNF3,APP,CDK13,ASCL1,N4BP2L1,ADGRB2,BMP7,SCAPER,MTMR3,CFAP410,CA12,CACNA2D1,MICAL2,DCAF4,MAML1,TRAPPC9,DRP2,DTNB,RASGRP2,NCALD,FABP7,DCTN2,SORBS1,NSG1,HBS1L,SIGLEC8,SRCAP,IGF1,ITGA7,KHK,VWA5A,MAN2A2,AFDN,TAGLN3,NEFM,CNOT4,PALM,PBX1,ENPP2,PHKG1,PLCD1,MTRF1L,PTCH1,RASGRF1,SCN2A,SLA,RPH3A,ZNF334,BTBD7,SNCA,TNIK,ARHGAP26,SPTAN1,RBM26,TMOD1,DAAM2,TNS1,TMPRSS5" Drug 5873_UP Nadide [53-84-9]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "MRTFA,PKP4,APC,ASTN1,ATP6V0A1,ST3GAL5,CACNG1,MAP7,KCNAB3,RAB26,AKAP7,PCYT1B,FAM149A,COL9A2,MICAL2,RABGAP1L,DLG3,DSCAM,DTNA,LPAR6,HSD17B14,EPHA5,DENND4A,REEP2,FCGRT,ZNF589,CGREF1,TBR1,HBS1L,HPGDS,POLL,PRRC2B,GPR19,KIF5C,VWA5A,MAPT,NPTX1,PAK3,MAPK10,KLK6,SAMD9,BCAS3,PTHLH,PTPRH,MYH14,ASAP3,TSNAXIP1,SEMA4A,TCF4,PCDHGA10,TEX15,CABIN1,HIRA,LMF1,WIPF1,XRCC4,ZIC3,SPHK2" Drug 5941_UP H-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ADCY2,AP2A2,NME5,LTBP4,ALK,AMT,APBB1,GAS7,APOC1,BCAS1,APP,CFAP410,NEURL1,ARHGAP33,CHRNB2,CLTB,CTNND2,ATN1,SIDT2,LRRC23,RASGRP2,CELF1,OGA,ERAP1,DISC1,GART,GATM,ALDH1L1,TXNL4A,GLYR1,GNAL,LPAR4,SPACA9,ELOVL5,KCNMA1,MAPT,MATN3,NEK1,NF1,CDK14,SLC25A23,FSD1,ZCWPW1,GAL3ST4,TCP11L1,SH3BP2,SLC1A7,PEX26,WDTC1,EMC1,BEX1,DDN,MAPK8IP3,PLCB1,TK2,VIPR2,SLC17A7,KCNAB1" Drug 6299_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ASPHD1,SLC12A5,PLA2G6,PPFIA3,PPP4R4,FUBP1,SCAPER,MYRF,RUNX1T1,SCARB1,ARHGEF2,FADS2,COL9A2,CREB5,ABCG1,ARHGEF10,PDE4DIP,SV2B,DTNA,TOM1,DUSP9,EDIL3,EFNA3,MRNIP,PLEKHO1,COQ7,IGSF6,RRAGB,SORBS1,DENND2A,ZMYND11,TMEM8B,GPR22,IL6ST,LIG4,NOVA1,NPR2,CLDN11,POLG,CNTLN,PTPRN2,RGS10,TCP11L1,SUPT20H,ZFP30,DZIP1,KDM4B,ZHX3,PHLDB1,ARHGEF9,CHST8,TIAM1,TK2,TPM2,HIRA,TRIM9,WNK1,SEMA3B" Drug 6330_UP Budesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ARID1A,ADORA1,LTBP4,EPB41L5,SEMA4G,ATP1A2,NRP2,HIP1R,ARHGEF1,CHRNB2,TPP1,ARMC8,CREM,AKAP12,NCOR2,PDE4DIP,SLITRK5,PHF14,TBC1D5,SPOCK2,RABGAP1L,DTNA,EFNA3,FAM13A,IRAK4,PIPOX,FGF1,HPCAL4,DENND2A,POLL,KLF12,IL6R,MIA2,MPP2,NF1,CNOT4,NRCAM,NUMA1,FSD1,MAPK7,IL17RB,ZFP30,SH3GL2,CNKSR2,PKNOX2,SLC20A2,SORCS3,SNCA,TNIK,KDM4C,SS18,CEP68,MLC1,TBCEL,TNS1,EVI5,SEMA3B,NAV2" Drug 7531_UP 0393-0188; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ADCY6,ADORA2A,AP2A2,PLA2G6,ALCAM,CDC42BPA,APBB2,RASL11B,ATP2B2,SLC2A11,ADAM23,ADGRB2,SCAPER,BAIAP3,CAMK2B,ARHGEF6,CSF1R,DZIP3,SRGAP3,SNX29,HIPK3,EGFR,EPHB1,CDKL3,PIPOX,ALDH1L1,RAB30,GNG4,NR3C1,GUCY1B1,HLF,HNMT,IL6R,LSS,MAP2,MAPT,MMP16,NFYA,CNOT4,NPY,NUMA1,NLE1,MYH14,EMID1,ASAP3,FNDC3A,LIMCH1,KDM4C,UNC5B,CLASP2,SS18,IQCE,WSCD1,PCDHGA10,TRIO,VSNL1,EVI5,SLC17A7" Drug 3821_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "DPF1,ADCY2,DOC2A,PPP4R4,ZSCAN18,MPDZ,MYRF,CDC42,SH2B1,MICAL2,PDE4DIP,SLITRK5,RIMS2,CTIF,MFAP3L,CHRDL1,DUSP9,AASS,EIF4G2,NCALD,ZNF549,SCML2,FGF1,FOXG1,FYB1,NEU3,C1QL1,GPR75,GNG4,CACFD1,ITGA7,LAMA2,MPP2,LYRM9,NAP1L1,NPR2,PDE4A,PDE4B,EPN1,POLG,PTPRB,ZSCAN2,RAD52,RGS10,TCP11L1,RXRA,ASAP3,SLC6A11,SNCA,DOK5,KDM4C,COLGALT2,ADGRL3,SLC44A1,TK2,TNS1,TRIO,CADM1" Drug 4581_DN Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ANK3,KCNAB2,BTRC,CACNA1A,ARHGEF1,ARHGAP33,TAOK2,PICK1,HINFP,ARMCX2,EXOG,EDNRA,SIDT2,FAM13A,ELAVL3,RGS17,LRRC23,RRAGB,FGFR1,CINP,PDLIM5,FYB1,C1QL1,STON1,GRIK2,MAP4,MMP16,LYRM9,NDP,PAK3,PROX1,SYTL2,PTHLH,RAD52,GAL3ST4,RGS10,ZNF671,IL17RB,ZNF821,AMBRA1,FBXO11,ANKRD6,PEX26,ARHGEF40,TNIK,ARHGAP26,MAPK8IP3,VAMP1,ASTN2,DOCK9,TNS1,SSBP2,VGF,VIPR2,LAT2,XRCC4,SF1,KCNAB1" Drug 5911_DN valinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ASPHD1,ADRB2,MTUS1,APBB2,SHROOM2,CDC14B,DNAH17,ALDH4A1,ADAM15,BCL7A,MTMR3,ARHGAP33,B4GALT6,PDE4DIP,DAPK3,MFAP3L,SPOCK3,SGSM2,MAMLD1,EN2,NCALD,OLFM1,ITGA7,MAPT,MN1,NAP1L2,NDP,NUMA1,ODF2,PCDH9,PIK3R1,POLG,PPP5C,MAPK7,WDR25,FAM120C,RAB3A,SH3TC2,IL17RB,ZNF821,ITSN1,DZIP1,OGDHL,SNCA,SPTAN1,SPTB,MAPK8IP3,VAMP1,COBL,MTCL1,KIAA0930,NACC2,TNS1,METTL3,NSD2,NDRG4,SPHK2,NUP214" Drug 2853_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "KIAA1324,AK2,PLA2G6,BIN1,ANK3,CNTNAP1,ALDH4A1,ATM,SLC2A11,CFLAR,MTMR3,CFAP410,EPS15L1,CREM,GREB1,SNPH,RASSF2,SPOCK2,ARMCX2,TMCC2,DTNB,ZNF589,KIAA1109,FGFR1,FAM49B,KHDRBS3,GAD1,GPM6B,GRM1,GSN,SYNPO,KCNH2,KCNJ3,MMP16,NEUROD1,NNAT,PIK3CD,PMS2,MINDY2,PRKAR1B,MAPK7,MAPK8,PLPPR1,FAM120C,RAB3IL1,RAD52,SBF1,SLC30A10,ASAP3,SLC1A7,SNCA,HECW1,PLCB1,ANKRD12,SPHK2,EVI5,GDPD5,ITM2C" Drug 4267_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "DPF1,ADD2,SYT13,ZSCAN18,KIF1A,KSR1,CACNA1I,CFAP410,CACNA2D1,CALB2,KALRN,ADGRG1,NCOR2,ARHGEF4,CTNND2,CDON,ATN1,EDN1,EPHB1,ZNF549,DLC1,KIAA1109,NSG1,GABRA2,TRAF3IP2,SEPT9,SRCAP,GFER,GNAO1,PRUNE2,LPAR4,KCND3,MOBP,MYH6,MYT1,NEUROD1,NNAT,NOVA2,KCNK10,EPN1,LRRN3,MAPK8,RGR,KLHL11,PNMA8A,SYNDIG1,SLA,SCN3B,WDTC1,SOX2,SS18,MCF2L,PCDHGB6,HIF3A,TK2,RIMBP2,PRDM2,MVB12B" Drug 2748_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "ABAT,ABHD6,AK2,MRTFA,APC,EPB41L5,ARRB1,ASPH,ATM,CFLAR,MTMR3,MAGI1,PLEKHB1,CREM,NCOR1,ABCG1,CSNK1E,LYPD1,GNE,VPS13B,NCALD,VPS26C,ZNF589,IQCG,OGA,DISC1,INPP5K,AHDC1,CACFD1,INPP5B,ITPKB,KCNF1,KCNH2,KCNJ3,MAP4,MAPT,KITLG,LYRM9,RETREG1,RGS10,ROM1,SBF1,SUPT20H,SMTN,SLC6A8,SLC15A2,ZKSCAN3,LIMCH1,MCF2L,TRIM2,PCDHA6,TMEM121,ZKSCAN5,HIRA,UBE2H,REEP1,EMSY,SEMA3B" Drug 5952_UP radicicol; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "MTUS1,OSBPL1A,NME5,EIF4G3,BID,CFLAR,SCAPER,CACNA1I,CACNG1,CBS,ARHGAP33,EPS15L1,ARMC8,CRY2,PDE4DIP,DZIP3,CTH,GIT2,FBXL5,DMPK,EDN1,SIDT2,EFNA3,ING4,ACSL4,ST3GAL6,BAIAP2,CAP2,AFF2,SORBS1,CGREF1,ERAP1,GLI2,GLYR1,DIDO1,MUM1,SYNPO,KCND3,MITF,NAP1L2,NPR2,OXTR,PIK3CD,SMIM7,PPARA,PTCH1,FAM120C,RGS10,IL17RB,HSPA4L,DOCK10,SLC1A3,PDZD2,ARHGAP26,ITPRID2,TRIM2,WIPF1,ZNF74" Drug 3124_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "BIN1,CDC42BPA,ANK3,FAM131A,BMP7,CACNB2,CAMK2B,NMT2,SULT4A1,COL9A3,CPS1,SH2B1,AATK,DCAF4,USP6NL,SV2B,SV2A,DYRK1A,EDNRB,EFNB3,CELSR3,TNK2,CEND1,FOXG1,C1orf61,GPR153,GAP43,SRCAP,PCDH17,GPM6B,KLF12,KIFC3,MARK1,TAGLN3,LYRM9,CNOT4,NOVA2,OMG,MAPK10,RELN,BCAS3,PTCH1,PTPRD,ZDHHC14,PRR5L,FOXRED2,SCG5,SLC1A3,RPH3A,PREX2,SLC11A1,BTBD7,SOX10,ZBTB43,KANK1,SZT2,BEST1,SCG2" Drug 6006_UP Nifedipine [21829-25-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.62E-07 2.75E-02 1.61E-05 1.84E-04 58 195 "C1QTNF1,LTBP4,BIN1,APAF1,ARHGDIG,CDK13,MARK4,ATP2B3,CADM3,CACNA1I,CAMK2B,CAST,NEURL1,CHM,OSBPL3,MAML1,DCT,DMPK,HS3ST2,DSCAM,USH1C,EDN3,RASGRP2,PIPOX,NRN1,CAMKK2,OGA,GABRA5,GAD2,GATM,NEU3,ALDH1L1,GLS,GUCY1B1,TJAP1,ITIH2,KCNN1,MYCN,CDK18,PDE1C,PDE4A,PDE4B,PGAM2,MTRF1L,PPARA,MASP1,SYNDIG1,LRRTM4,SLC6A9,SLC11A1,ATP10B,DOCK9,CRTC1,THRA,TRPM2,MICAL1,LAT2,PRDM2" Drug ctd:D003913 Dextroamphetamine CTD 5.66E-07 2.77E-02 1.63E-05 1.85E-04 56 186 "ADRA1B,AGT,ATP1A2,ATP2A2,MYOM1,BID,CDK5R1,CACNA1G,CAMK2B,CAMK2D,CCNT1,CDH2,CHRM1,CNR1,CREM,CRHBP,CSF1,DCC,EIF4G2,TUBB3,FGFR1,FOXG1,GAP43,GDF1,GFAP,GNAL,GPER1,NR3C1,GRM1,GRM5,GRM8,HSP90AA1,HTR5A,HES5,MAOB,MYH7,NOS1,NPY,NTRK2,PDYN,PENK,MAPK3,RDX,RGS4,STX1B,SIRT2,SNCA,STX1A,ARC,SYP,SYT5,TAC1,TACR1,ATP13A2,SCG2,SLC17A7" Drug CID000134664 benzodiazepine Stitch 5.82E-07 2.85E-02 1.67E-05 1.90E-04 46 142 "ABAT,ADORA1,ADORA2A,ADORA3,ARSE,CACNA2D1,CBR1,CCK,CCKBR,CHRM1,CHRNA4,CHRNB2,TOX,DBI,GPHN,STX2,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,ATP8A2,GLRB,LOXL3,GRIK1,GRIN2C,GRIN2D,GRM5,HTR2A,KCNK3,MAOB,OPRL1,PTCH1,SLC1A2,SLC6A1,SLC6A11,ZEB1,SMUG1,PCDH15" Drug CID000002703 chelerythrine Stitch 5.99E-07 2.94E-02 1.72E-05 1.95E-04 92 357 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,DGKZ,DGKD,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,DGKI,LRBA,CHRM1,MYL6B,CTH,DGKB,DGKG,DBI,SLC12A6,EDN1,EDN3,EDNRA,EGFR,PTK2B,ACTL6B,GNAS,GRIA1,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,HTR2A,MYLK2,SCIN,JAK1,KCNJ4,MYL3,NOS1,NPPA,OPRL1,OXTR,P2RX7,PDE2A,PDYN,PIK3C2A,PIK3CD,PIK3R1,PKM,MBOAT7,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,PSMA6,PTK2,MAPK12,SMPD3,SLC1A7,SLC9A5,SLC12A4,STAU1,MLC1,TAC1,ACTR6,CABIN1,CDK20,TRPC1,PLD4" Drug CID000005365 4-methylglutamic acid Stitch 6.04E-07 2.96E-02 1.73E-05 1.97E-04 17 31 "BCS1L,HDAC9,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM3,GRM5,SLC1A2,SLC1A3" Drug CID000108099 NPC 12626 Stitch 6.04E-07 2.96E-02 1.73E-05 1.97E-04 17 31 "SEMA4D,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KITLG" Drug 6829_DN Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ALCAM,MRTFA,MARK4,ALDH4A1,CFLAR,ST3GAL5,SYNJ2,CACNA1D,FOXN3,CREM,SH2B1,CRY2,NCOR1,HDAC4,SLC12A6,DTNA,TOM1,EDNRA,SUGP2,PLEKHO1,RRAGB,FER,CAMSAP1,OGA,SRCAP,GRB10,BTN2A1,IGSF1,INPP5B,ITPKB,JAK2,KCNH2,MAP4,GIT1,NFYA,PRODH,RAD52,RGS10,RGS12,CCDC25,RPS6KA2,SBF1,SGK1,SH3BP2,RAB3GAP1,COA1,SNCA,SPTAN1,PHLDB1,SEMA4A,EXOC7,IQCE,TCF7L2,ZNF34,BHLHB9,TPM1,PLPPR2,GDPD5,HPS4" Drug 2713_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "BEGAIN,BIN1,FGD2,CHRD,CCDC181,ADGRB1,BTRC,CAMK2B,LARGE1,CHN2,CLCN4,CNR1,PICK1,CNTN1,ABCG1,RIMS3,DAPK1,CNIH3,ABCC9,FGF12,AMOTL2,FOLR2,SORBS1,GPR153,NSG1,SIGLEC8,GFER,LYVE1,GPM6B,GRIN1,GSN,HTR2A,ICA1,KCNK1,KIF5C,KIT,LAMA2,MAPT,MBP,CD200,NTRK2,PDE4D,PGAM2,PLCL1,PLP1,NECAB2,SPATA6,POU3F2,PTPRH,CCDC40,MYH14,ANKRD6,SHANK2,ACSBG1,TIAM1,RPRM,FLRT1,PRDM10,PLSCR4" Drug 5784_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ACTN2,ADORA1,SLC4A4,ATP2B2,KSR1,BAIAP3,CACNA1D,CD86,CHN2,ARHGAP22,PLAA,LY86,HOMER3,AKAP5,ABCG1,DBT,DCT,PLPPR4,EDN1,CNNM1,PLEKHO1,FGF1,PRELID3A,FYB1,GABRA2,SRCAP,LILRA2,STON1,CNTRL,GSN,ELOVL5,KCNB1,KCNJ5,VWA5A,MAN2A2,AFF1,TAGLN3,NRCAM,PDE2A,PDE4D,TNPO2,PPP2R2B,ACSS3,KCTD17,SYNDIG1,ZNF821,STUM,SNCA,PDZRN3,KDM4B,SCN3B,BEX1,ARHGAP26,MCF2L,TRIO,WIPF1,EVI5,SEMA3B,DPF3" Drug 5785_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "DPF1,TTYH1,ADRA1D,BBOX1,AMH,ATP6V0A1,BMP7,CACNB2,NEURL1,CDH8,ADGRG1,CHN2,LHX2,EPS15L1,HOMER3,CNTN1,COL9A2,AKAP5,CSF1,PLXNC1,TENM1,ELAVL3,COQ7,FGF1,OLFM1,PRELID3A,GRM1,GSTM5,NXPH3,HMX1,KCNA2,KCNC1,KIT,MAPT,ADAM22,TAGLN3,NCAM2,NTRK3,PDGFRA,POLG,PKN2,DIRAS2,CCDC40,RAD52,ENOX1,KCTD17,ROM1,TMEM206,SYNDIG1,SH3BP2,DZIP1,INKA2,KIAA1107,RALYL,BHLHB9,SEZ6L,RUNDC3B,MKRN3,SLC17A7" Drug 2503_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ANK3,PDE8B,ATP1A3,BACH1,CACNA1G,CACNB4,CRLF1,CHRNA4,TAOK2,ZFYVE9,CREM,CRY2,RGS6,PDE4DIP,DZIP3,PITPNM3,KIAA0513,DYRK1A,FCF1,CELSR3,PLXNC1,ING4,FGFR3,PDLIM5,DKK3,GAB1,GATM,GPM6B,GSN,HAS2,KLF12,SYNPO,HTR2A,KIF5C,MEF2C,AFDN,ADAM22,FSD1,PRKAR1B,RIPOR1,SYNDIG1,RTN1,SEMA6D,CCDC88A,TMCC1,PEG10,SPTAN1,ATP10B,TROVE2,MAPK8IP3,TBCEL,TRIM2,AP4E1,GPR161,TIAM1,TRPC3,SSBP2,TUBB1,KCNAB1" Drug 3549_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ACTN2,CDC42BPA,SLC2A11,CACNA1I,USP2,MTMR7,DGKI,MYOM2,QKI,HOMER3,CNR1,RCHY1,IPCEF1,CNTNAP2,PPP6R2,CTIF,MYEF2,DLG2,ATN1,CNNM1,EN2,GABRA2,RND1,GPM6A,GPM6B,LILRA2,GPER1,GRM1,GRM8,PTGDR2,TJAP1,KCNH2,KHK,MATN3,MGAT3,AFDN,ADAM22,NF1,PALM,ABCB1,PLCB2,NECAB2,SEPT4,PPP5C,CCDC40,RALGDS,PNMA8A,ZFP2,SELL,KDM4B,ATP10B,TBCEL,TCF4,TMEM151B,PSD3,OBSL1,TNS2,SLC17A7,SENP7" Drug 5730_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "AGT,FAM135A,SYT13,CDC42BPA,CDK10,DDX3Y,ALDH4A1,ATP1A2,CACNA1G,CACNB2,ARHGAP33,CLU,SULT4A1,PICK1,COL9A3,AKAP5,CSF1R,PHF14,RIPOR2,CTIF,AK5,HS3ST2,DTNB,EDN3,EGFR,RGS17,LRRC23,FGF1,FGFR1,AFF2,COPS8,GPR19,HSD17B1,ITIH2,KCND3,LSS,MSI1,NOVA1,NRCAM,GPR173,POU3F4,PPP5C,GDPD2,PTPRB,RFX2,RGS3,RGS12,SLC6A8,OGDHL,SOX15,HECW1,ZC3H13,LHPP,SYN2,PCDHGB6,UCHL1,ZNF74,PRDM2,PARP11" Drug 1492_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "SLC12A5,PLA2G6,SYT13,MRTFA,AMT,CDC42BPA,CDC14B,MARK4,CFLAR,ST3GAL5,SCAPER,CA12,CACNA1D,CACNA2D2,TAOK2,NMT2,STOML1,NCOR2,FAM169A,ING4,TUBB4A,FGFR3,BAIAP2,AHDC1,POLL,TDRKH,ADAMTS13,GRIN1,CACFD1,KCNH2,KCNN1,KIT,MAP4,MID1,NEUROD1,OMG,PCDH9,CDK18,PLCD1,PMP22,LRRC49,SEC14L1,ZNF821,SH3BP2,ASAP3,CNKSR2,FAM214B,SLC15A2,OGDHL,RBM34,HECW1,UNC5B,STX1A,ATP11A,IQCE,TCF4,TMOD1,CABIN1,SLC17A7" Drug 2543_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "BCAR3,BBOX1,AMH,BIN1,ATP2B2,B3GALT2,AZGP1,RGS11,CACNA2D1,CACNB4,CAMK2A,CHRNA4,NRG2,HAPLN1,CRYBB1,ARHGEF10,PLCH2,NOS1AP,BRINP1,HS3ST2,ST8SIA3,SEZ6L2,EDN3,TNK2,SRPK3,HSD17B14,ERBB2,GPD1,LILRA2,STMN2,GRIN2C,SOX21,RASSF8,ITGAM,ITIH2,KCNH1,PACRG,MATN2,MDFI,MMP16,MPP2,PPP1R1A,SLC6A15,RFX3,KCTD17,ASAP3,CCDC92,SOX2,CLSTN2,ACSBG1,ADGRL3,KIAA1107,DOCK9,SPX,TK2,OSBP2,WNT7A,ZBTB38,STMN4" Drug 4084_UP Moxonidine [75438-57-2]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "SEMA6A,LTBP4,ASCL1,FUBP1,USP2,SLC16A4,KCNAB3,CHN2,CLCN4,VAX2,RGS6,PLCH2,PYGO1,C2CD2L,MAGI2,SPOCK3,ARNT2,EDIL3,RASGRP2,IGSF6,ZNF391,REEP2,CAMSAP1,GATM,ALDH1L1,GRIA1,GRM8,HRH3,KLF12,HPCA,KCNJ3,MMP16,MYCN,NCAM1,NF1,PBX1,ENPP2,DIRAS2,CCDC40,RNASEL,EMID1,STUM,NTNG1,SLC15A2,TNIK,HECW1,ZC3H13,ARHGAP26,DDN,SS18,MAPK8IP3,TAL1,TEX15,DICER1,GPR161,TMOD1,TRPC1,KCNAB1,HRASLS" Drug 4002_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ABAT,AP2A2,PLA2G6,DOC2A,AMH,KIF1A,ADAM23,KSR1,BAIAP3,BTRC,CACNG1,CALB2,THSD7A,CLDN10,TPP1,ENTPD4,CRY2,SUSD5,NCAN,RIMS2,SMG7,DYRK1A,ABCC9,TENM1,FABP7,NSG1,OGA,GNAL,GPM6A,LILRA2,GRIN1,CACFD1,IL12A,KCNF1,MARK1,CD200,NCAM1,NEFM,NLE1,PPP2R2B,BEND5,PNMA8A,CCDC102B,MRAS,FUZ,SOX10,HECW1,NFASC,PHLDB1,ACSBG1,KLHL4,SLC44A1,TPM3,CHST5,FLRT2,VGF,ZNF225,WNK1,MVB12B" Drug 2912_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "C3orf14,ADORA1,PLA2G6,ALAD,CDC42BPA,ANK1,ANK3,PPP4R4,ATP6V0A1,NRP2,CACNA2D1,SCARB1,B4GALT6,TAOK2,CLCN4,CREM,ABCG1,TRAPPC9,OPTN,EFNA3,MRNIP,PLEKHO1,CDHR1,ST3GAL6,FER,BAIAP2,GAA,SEPT9,PCDH17,GPR75,ATXN2L,HNMT,KCNB1,KIFC3,GIT1,ZNF862,NINJ2,PDGFRA,EPN1,CEP41,MAPK10,CNNM2,DEF8,PTPRN2,RGS10,SEC61A2,PBRM1,TCP11L1,FRMPD1,EPN2,PKNOX2,TSNAXIP1,ZSWIM8,UNC5B,IQSEC2,SPART,VAMP1,ZFP37,SPHK2" Drug 5991_UP Phenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "DPF1,NR0B1,PLA2G6,SYT13,KCNAB2,APP,PPP4R4,GPR37L1,RCBTB2,ZFYVE9,FAM189A2,ARHGEF6,SMARCAL1,ST18,NOS1AP,TMCC2,DTNA,EGFR,TENM1,VPS13B,DMTN,RASGRP2,CORO2B,FGFR3,FHL1,GAB1,ATP8A2,ALDH1L1,GFER,GRIK1,IRAK3,KCNH2,KCNJ4,KITLG,MMP16,MOBP,ADAM22,PDE3B,PDGFRA,RETREG1,NECAB2,TMEM231,KLHDC8A,CARF,TCP11L1,EMID1,ASAP3,SYBU,SLC8A1,SLC22A4,SMARCD3,ZCCHC24,EMC1,KDM4C,PLCB1,SLC44A1,CABIN1,RUNDC3B,LAT2" Drug 3528_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "NDRG2,FAM131A,AQP4,ARSE,DNAH17,DDX3Y,NRP2,BTRC,CFAP410,CACNB2,SEPT7,CDH10,CACNA2D2,ADGRG1,PLEKHB1,NDST3,AKAP7,ENTPD4,CLIP3,CSF1R,OSBPL3,RASSF2,DBT,CDON,ATN1,HIPK3,RASGRP2,ZNF589,TPK1,TPPP3,FYB1,GALC,SEPT9,ATP8A2,ALDH1L1,RND1,GNG4,GPD2,GPER1,GRIA1,GRIN1,GRM7,KLF12,ITGA7,ADAM22,NPPA,NTRK2,OLR1,NECAB2,MAPK7,PSD,ZFHX4,TCP11L1,SLCO1A2,MAPK8IP3,WSCD1,PSD3,VAV2,VGF" Drug 3057_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ADGRF5,SPARCL1,SEMA6A,ANK2,PPFIA3,CDC14B,DDX3Y,FUBP1,CACNA1I,CACNA1G,MAP7,LHX2,SEC14L5,ZNF337,DGKG,NTM,ST8SIA3,SRPK3,OLIG2,EPB41,ERBB4,APC2,B3GAT1,TBR1,GAP43,NEU3,MSTN,ZNF276,GPR75,GNAL,MCHR1,PCLO,PTGDR2,HTR5A,KCNC1,MYO7A,NF1,PDGFRA,PENK,PLP1,PMP2,FSD1,DCHS2,KLK6,PTH1R,RAB3IL1,CRTAC1,RGS10,RGS12,MYH14,KLHDC8A,MAP6D1,PALLD,RALYL,SLC19A3,CRB1,AP4E1,SEZ6L,PMEPA1" Drug 4953_UP Nifurtimox [23256-30-6]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "ASPHD1,AP2A2,NME5,LTBP4,BIN1,FAM131A,ARHGDIG,CHRD,SLC4A4,CBFA2T2,ARHGEF2,ARHGAP33,FADS2,HOMER3,SH2B1,RUBCN,ELMO1,MFAP3L,RUSC2,PARD6A,EDN3,SIDT2,SORBS3,MTSS1L,GATM,GCNT2,SRCAP,C1QL1,ATF7,PCLO,KCND3,MOBP,NEFM,CNOT4,PCBP3,P2RY1,PDGFRA,PPP2R2B,VPS13C,PTH1R,KLHDC8A,DZIP1,PKNOX2,SLN,CXXC4,PLCB1,SYN2,POPDC3,SMG6,WSCD1,TCF4,DOCK9,CABIN1,TRIO,XRCC4,ZNF711,SLC30A3,SCG2,SEMA3B" Drug 5521_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "CDC14B,PLA2G4C,MYRF,CAMK2B,CAST,EPS15L1,QKI,IFFO1,ENTPD4,CRMP1,FEZ1,RIMS2,CYBB,MYEF2,MFAP3L,TMCC2,EFNB3,VPS13B,KAT8,FGF1,OLFM1,DCTN2,TPK1,KLF12,KCNB1,KHK,IPO5,MAN2A2,MSR1,ZNF862,CYTL1,CDK14,GDPD2,PLPPR1,PTPRE,ZDHHC14,RGS7,ROBO1,RPS6KA2,SLA,SLC2A5,KANSL3,LIMCH1,TNIK,ERC1,SPTAN1,THSD1,STX1A,SYT11,ROBO3,TAL1,WSCD1,KIAA0930,HEY1,CABIN1,ZKSCAN5,VGF,MAP3K12,SLC17A7" Drug 5917_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "KIDINS220,NME5,C1QTNF3,TRMT9B,APC,APP,CDK13,ASCL1,SLC4A4,CFAP410,CD86,CDH18,NCOR2,ARHGEF10,SIDT2,ELAVL3,SRPK3,IGSF6,PTK2B,TDRKH,PCLO,SPACA9,IL6R,KCNMA1,IPO5,MID1,MMP17,BCO1,MYO7A,NEK1,NF1,NTRK2,PALM,PTAFR,PTHLH,FAM120C,ZSCAN2,RGS3,TCP11L1,RPS6KA2,CLIP1,FOXRED2,ASAP3,FNDC3A,SLC4A3,SLC11A1,SS18,KAZN,SMG6,RPGRIP1L,PCDHA5,TK2,TNS1,HIRA,SPHK2,SLC30A3,SCG2,MVB12B,PHTF2" Drug 4820_UP Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.11E-07 3.00E-02 1.73E-05 1.97E-04 59 200 "TRMT9B,N4BP2L1,ADGRB3,FGF17,KSR1,BAIAP3,CACNB2,RHBDL1,CLDN10,INA,CDH8,SLC24A2,CSF1,RIMS2,DCAF4,SPOCK2,BRINP1,SPOCK3,DMPK,EPB41L1,LRRC17,ANKMY1,F5,ST3GAL6,DPYSL4,DENND2A,ARPP21,GAP43,ATP8A2,GNAS,PCLO,RAPGEF1,IGF1,TJAP1,ITIH2,KCNH2,AFDN,MYH7,NF1,NPPA,OLR1,PIK3CD,EPN1,SAMD9,RGS12,SYNDIG1,RYR1,ZFP2,MRAS,SLC2A5,CCDC88A,SLC11A1,CLSTN2,COLGALT2,SYT11,R3HDM1,FAM155A,DNALI1,NUP214" Drug 4190_UP Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.21E-07 3.04E-02 1.76E-05 2.00E-04 57 191 "RALGAPA1,NDRG2,SEMA6A,ANK1,APC,KSR1,CARS,HIP1R,SCARB1,ARHGEF2,LARGE1,TPP1,ABCG2,WHRN,AKAP5,PDE4DIP,CNTNAP2,EDN3,CEND1,ZNF589,C1orf61,GAB1,B4GALNT1,SYT17,RND1,GLI2,GNAL,GNAO1,AP4S1,PTGDR2,KLF12,KIT,AFDN,NF1,PDE3B,SERPINI1,PPARA,PTPRG,RAD52,C1orf54,RGS4,TMEM206,KCNIP1,ATXN1,FAM102A,NFASC,INKA2,MAPK8IP3,SYT5,PCDHA5,HEY1,TPM3,TRO,ZMYND8,FLRT2,VSNL1,KCNAB1" Drug 5917_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.21E-07 3.04E-02 1.76E-05 2.00E-04 57 191 "ADORA1,BEGAIN,KCNAB2,PRX,MARK4,ALDH4A1,ATP6V0A1,RGS9,CACNA2D1,NGB,SEPT7,CDC42,CHRNA4,PICK1,CNTN1,ATRNL1,DCAF4,EDRF1,RUSC2,TMCC2,DTNB,EDN3,EFNA3,MBNL2,EGR3,ING4,FYN,ATF7,ADAMTS13,NR3C1,GRM1,GRM3,ELOVL5,TJAP1,KCNJ4,VWA5A,MDM4,ADAM22,PLCB2,TNPO2,MINDY2,PTPRE,RAD52,KLHDC8A,RYR1,STUM,ZNF365,PREX2,NMNAT2,EMC1,HECW1,DOCK9,ARHGEF12,OSBP2,NAV2,SLC17A7,UBE3B" Drug ctd:D012906 Smoke CTD 6.49E-07 3.18E-02 1.83E-05 2.09E-04 203 938 "SERPINA3,ASPHD1,ACHE,TMCC3,USP31,AGT,TAOK1,SRPX,BIN1,APBA2,EPB41L5,LGR5,ZFYVE28,PDE8B,BACH1,BCHE,PROM1,DST,SYNJ2,CA12,DDR1,CH25H,MAP7,CBR1,USP6,SCARB1,ARHGEF2,CDH2,ADGRG1,B4GALT6,KMT2C,RPL32P3,CLU,FADS2,ABCG2,CP,GDA,AATK,SNCAIP,CSF1R,FEZ1,SUSD5,VCAN,SLITRK5,PITPNM3,PPP1R16B,GREB1,CX3CR1,NOS1AP,RIPOR2,SNPH,TOX,DGKG,SPOCK2,AIF1L,GIT2,ARMCX4,ARMCX2,MYEF2,DYNC1I1,DOCK2,EDNRA,EDNRB,SYT15,RASGRP1,EGFR,ELAVL2,RGS17,PCOLCE2,ETV1,ABCA8,SH3YL1,PTK2B,ST3GAL6,FCGR3A,FGF13,FLNC,SYT3,DPYSL4,SORBS1,SPECC1,RASL10A,PNMA2,GALNT15,B4GALNT1,NEK6,SYT17,DISC1,ATP8A2,ACSS1,DNER,GCNT2,SRCAP,PPARGC1A,GLDC,MAP7D2,PCLO,GRID1,ZNF496,GSN,GUCY1B1,ATOH8,PADI2,NEGR1,HSP90AA1,IGF1,ZNF385B,KCNJ16,KCNK1,L1CAM,NCOA7,GPR155,MAOB,MATN2,MBP,IL17D,MEF2C,SAMD5,MSR1,MT3,MX1,MYO6,BEX5,NAP1L3,NEFH,NFE2L2,NME4,NOVA1,NRCAM,OGG1,OLR1,CLDN11,OXTR,PAK3,PALM,PBX1,PDE4B,CDK14,ABCB1,SERPINI1,PIK3C2A,PIK3R1,PLXNB1,EPB41L4B,FA2H,SH3KBP1,MAPK3,EPDR1,PROX1,KLK6,SYTL2,LAMA1,PTCH1,ELOVL2,SPDL1,ZIK1,ACSS3,FAM66C,MRAP2,SNX22,FBXW7,RYR1,TMEM156,MAPK12,SEC14L1,MRAS,PPP1R9A,CPEB3,ST6GAL1,ABLIM3,SMTN,SIRT2,EFHD1,SLC22A4,ZNF415,PDZD2,ZCCHC24,SOX15,SPP1,UNC5B,KANK1,SULF2,ACSBG1,SYNE2,SYT1,COBL,SATB2,SIRT1,CHST8,TLR4,HEY2,TPM2,TPM3,TRO,TUB,UCHL1,FLRT2,PORCN,FMN2,TCEAL7,REEP1,TTC7A,DPF3" Drug CID000001329 DPCPX Stitch 6.54E-07 3.20E-02 1.85E-05 2.10E-04 40 117 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,SLC4A4,ALDH7A1,BSN,CACNA1A,CACNA1B,CACNA1E,SPAG9,P2RX6,ENTPD2,LRBA,SLC29A4,DRD1,LPAR4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM8,KCNJ5,P2RY13,P2RX7,P2RY1,PRKACB,PRKCB,PRKCG,PTPRB,ZDHHC4,P2RY12,ZIC3" Drug 2501_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ANK3,SEMA7A,APC,RASL11B,BCL2L2,BTRC,CA12,THSD7A,CDH10,CDO1,SLIT2,CLCN4,STOML1,SULT4A1,CNTN1,ABI3BP,CREM,DCAF4,MAGI2,EXOG,DTNA,HIPK3,FAM13A,MBNL2,ZNF549,TUBB4A,AFF2,GAD2,SEPT9,GPR22,IL1RAPL1,NPPA,NTRK2,NUCB1,SETD4,OMG,PDE4D,PLCL1,PRKAR1B,MARCH1,PPM1E,SLCO1A2,SLN,SNAP25,SPART,FAM168A,ZEB1,RPGRIP1L,ATP13A2,TK2,TMOD1,KCTD2,PARD3,TPM1,TPM3,VIPR2,KLC2,SLC17A7" Drug 2793_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ADORA1,ADORA2A,SPARCL1,BIN1,KCNAB2,CFLAR,SYNJ2,CACNA1I,INA,CDC42,CACNA2D2,RCBTB2,ASIC3,TAOK2,COL9A3,CNTNAP2,DCAF4,GIT2,HIPK3,HSD17B14,SORBS1,PDLIM5,USP19,GNG3,NR3C1,GRM7,GSTM5,ICA1,IL6R,BCO1,NDUFA5,PIK3CD,CCSER2,PLTP,RETREG2,MINDY2,FAM120C,C1orf54,ZDHHC14,RFX2,RGS3,RGS12,MYH14,RPS6KA2,ASAP3,SYBU,SMARCD3,TSPYL2,ST5,VAMP1,TRIM2,PCDHGA1,CABIN1,NDRG4,SEMA3B,KAT6A,SSPN,AP3B2" Drug 3106_UP Chrysin [480-40-0]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "TKTL1,AP2A2,AMPD3,BIN1,PLA2G4C,MPDZ,BMP7,CACNA1I,LDLRAD4,CAMK2B,CDH2,CREM,SH2B1,DZIP3,GPRASP1,SNPH,TM9SF4,DNAJB6,ANKRD46,SORBS3,LRRC23,CDKL3,CEND1,HBS1L,ZNF276,GPR22,GRIK5,KLF12,HTR2A,LSS,MYO6,FXYD7,OMG,NLE1,SMIM7,LRRN3,CEP41,BCAS3,RORB,NEK11,RPS20,PAQR6,SCG5,SH3BGR,SH3GL3,BCAN,PEX26,CXXC4,MYH15,SOX15,HEY1,CBX5,RPRM,LMF1,SYNC,PRDM2,STMN4,SLC17A7" Drug 5926_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "RALGAPA1,ASIC1,ADORA2A,ADRA1D,PLA2G6,C1QTNF1,BIN1,CDC42BPA,APBA2,APC,DDX3Y,CFLAR,CAPN3,CLGN,CHRNA4,CLU,TPP1,COL9A3,RIMS3,RABGAP1L,SNX29,FGFR1,GAD1,STON1,GPER1,ATXN2L,ELOVL5,IL11RA,MAP2,MID1,MMP16,ZNF862,NDUFA5,NEK1,NPR2,PCDH9,SERPINE2,PLEC,MAPK7,RELN,WDR25,RNASEL,EMID1,ZNF821,ASAP3,ST6GAL1,NLGN1,LIMCH1,SNCA,FAIM2,WDTC1,ATP10B,AJAP1,TAL1,OBSL1,HEY1,AMOT,SLC30A3" Drug 3682_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ABAT,NDRG2,ADD2,AMH,GAS7,ARHGDIG,ATP2B2,KSR1,MYRF,CACNA1D,LDB2,CHN2,NRXN3,HAPLN1,ABCG1,ATRNL1,MFAP3L,MAGI2,DMD,EDN1,FRY,EFNA3,ZIC4,KAT8,ANKFY1,GPM6A,LILRA2,GRM7,PADI2,IL12A,KCND3,KCNN2,MARK1,MMP16,TAGLN3,LYRM9,NDP,NNAT,NPR2,KCNK10,PDE4A,PLP1,MTRF1L,POU3F4,RGS7,IL17RB,DOCK10,CNKSR2,SLC11A1,SLC14A1,SNAP25,SZT2,GPR161,TNS1,ZMYND8,OSBP2,NUP214,JPH3" Drug 3210_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "CDC42BPA,PPP4R4,PTCH2,N4BP2L1,AZGP1,BAIAP3,CA4,KALRN,MAGI1,CHN2,RAB33A,TPP1,BAG4,CRY2,PLCH2,SIPA1L1,CNTNAP2,ARHGEF4,SPOCK2,DLG3,USH1C,EDNRA,EGFR,FABP7,DCTN2,TRAF3IP2,HBS1L,ERAP1,GNG3,PRUNE2,GRK4,TPPP,GRIN1,NR3C1,ATXN2L,C2orf72,INPP5B,KCNC1,MYCN,NOVA2,NRGN,PLCD1,MBOAT7,SBF1,SCN2B,SH3GL3,ASAP3,SLA,SMTN,SLC11A1,SHANK2,ATP10B,PHLDB1,ACSBG1,ARC,PSD3,TK2,SLC30A3" Drug 3763_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "AMPH,APBB1,BCAS1,PDE8B,ATP6V0A1,SCAPER,CACNA1I,CA8,KALRN,SYNGR3,CLCN4,SULT4A1,EDNRB,EPHB1,NCALD,FGF1,OLFM1,BAIAP2,ADAM28,GNAL,GRIK2,GRM1,GRM2,SOX21,KLF12,ICA1,KCNK2,KCNQ3,MGAT3,ADAM22,MYO7A,SLCO1C1,NUMA1,TREM2,PCDH9,CDK18,PDE2A,SPATA6,TNPO2,PTCH1,PTN,CCDC40,RAD52,MYH14,STK32B,ARHGEF40,BTBD7,DOK5,ATP10B,ACSBG1,EXOC7,TNS1,TRO,VIPR2,EVI5,PARP6,KCNAB1,NLRP3" Drug 3571_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ACTN2,ARID1A,KCNAB2,EPB41L5,SEMA4G,ASCL1,ATP1A2,RGS9,SYNJ1,BAIAP3,THSD7A,USP2,CD86,CBFA2T2,FOXN3,ASIC3,HOMER3,ARHGEF6,CRY2,RIMS3,DAPK1,CTIF,MAGI2,DTNA,DTNB,EFNA3,PLXNC1,ELAVL3,DMTN,KAT8,CAMSAP1,KHDRBS3,GABRA2,GAD2,GRM1,ELOVL5,AFDN,GIT1,NEUROD1,NF1,NFYA,ENPP2,PLEC,FAM120C,FRMPD1,ASAP3,PKNOX2,ARHGAP26,DDN,ATP10B,CLSTN2,VAMP1,PLCB1,ROBO3,TNS1,ZIC3,GDPD5,SSPN" Drug 4491_DN Althiazide [5588-16-9]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ASIC1,AK2,ALK,KCNAB2,APC,ALDH4A1,SLC4A4,CDK5R1,SCAPER,MYRF,IL33,SCARB1,ARHGAP33,IQCK,ARMC8,SLC4A8,CSNK1E,RUSC2,ABI1,EDNRA,EGFR,SPEG,CDKL3,ETV1,ANKMY1,KIAA1109,SORBS1,FYN,GAB1,TRAF3IP2,DENND2A,GART,KCNMB4,GPR19,GPR37,SHISAL1,KCNJ5,KIF5C,LSS,MDFI,MEF2C,PTCH1,ZCWPW1,ZDHHC14,ZNF821,BCAN,SLC20A2,OGDHL,SMARCD3,WDTC1,SPTAN1,SYT11,R3HDM1,TNS1,TPM2,ZNF711,ZNF24,DPF3" Drug 1546_UP Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "NDRG2,ADORA1,LTBP4,BEGAIN,CDK10,SEMA4G,SLC4A4,CA12,CACNA1A,CALB2,CACNA2D2,CNTFR,IQCK,COL9A2,SH2B1,CTIF,TMCC2,TRAPPC9,SORBS3,TMEM35A,CEND1,C1orf61,GAP43,GJB1,GNAO1,CACFD1,KCNF1,LAMA2,MBP,MMP16,GIT1,NPPA,NRGN,OMG,DUSP26,CAMKV,PRRX1,PACSIN1,PPARA,PPP5C,PTN,PTPRN,ARHGEF10L,PLPPR3,RXRA,SH3BP2,ITSN1,BCAN,LIMS2,FAM214B,SLC11A1,SYN2,CRTC1,DNAH7,LILRA4,VGF,CAMK1G,NUP214" Drug 4358_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ARID1A,ADCY6,ALK,MRTFA,CDC42BPA,APBA2,APBB2,APOC1,MARK4,RIPK1,BCL7A,GYG2,CA12,CAMK2G,NEURL1,ARHGAP33,ADGRG1,LHX2,CNTFR,CNTNAP2,MAML1,MFAP3L,SMG7,HIPK3,VPS13B,LRRC23,FOXG1,GALC,RND1,GRIK5,ARHGAP19,DHX35,IL6R,KCNH2,MMP16,NDUFA5,NF1,NTRK2,NLE1,MAPK7,CCDC40,ZFHX4,RASA3,SH3BP2,SMARCC2,DOP1A,EMC1,ARHGAP26,VPS13A,PLCB1,KIAA1107,TCF7L2,TMEM121,HEY2,CDK20,RUNDC3B,VAV2,SMIM8" Drug 6063_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "BIN1,GAS7,ALDH7A1,RGS9,NRP2,CACNA1I,MTMR7,CD38,CDH2,CHI3L2,HAPLN1,AATK,DCC,SPOCK3,ATN1,DUSP9,ST8SIA3,SRPK3,CEND1,AFF2,FYB1,ALDH1L1,ADAM28,PCLO,GRM8,HPSE2,HNMT,ICA1,IGF1,ITIH2,KCNMA1,KIT,AFDN,NOVA1,KCNK10,SPATA6,PROX1,RELN,PTPRO,RASGRF1,KHDRBS2,RGR,SCN8A,SLC4A3,SLC11A1,SNAP25,ZSWIM8,IZUMO4,HECW1,MAPK8IP3,TAL1,PCDHGB6,OBSL1,SEZ6L,MICAL1,LAT2,ZNF711,PRDM2" Drug 4092_DN Fillalbin [4540-25-4]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "AMH,CDK13,MARK4,ASTN1,CACNA1I,BAIAP3,CACNG1,BRSK2,ZFYVE9,ABCG2,DNAJB5,HOMER3,AKAP5,CSF1,DZIP3,EDRF1,DAPK3,RUSC2,ABCC9,EDNRB,PLXNC1,ZNF549,ETV1,ST3GAL6,KIAA1109,FGFR1,EFCAB2,SEPT9,C1QL1,GNAL,KIF5C,LIFR,MATN3,NF1,NNAT,ODF2,P2RY1,PDE4D,NLE1,MINDY2,PLPPR1,KHDRBS2,SLC6A15,RGS12,TCP11L1,RPS20,SLC1A6,SNCA,SUPT5H,ROBO3,MCF2L,FBXW11,TK2,R3HDM1,HIRA,OSBP2,VGF,PARP11" Drug 4741_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "DPF1,AP2A2,ADGRF5,SEMA6A,MRTFA,AMPD3,BIN1,APOC1,SEMA4G,AZGP1,CFAP410,CDH2,CDH8,CHGA,CNN3,AKAP7,HAPLN1,RASSF2,DCC,RUSC2,SPOCK3,DMPK,FHL1,SIGLEC8,GLI2,GNAL,GPR37,SPACA9,GRM8,GUCY1B1,VSIG4,HPSE2,TJAP1,KCNH2,KCNJ5,VWA5A,AFDN,MOBP,ADAM22,MYO7A,OPCML,EPN1,PLTP,LRP12,PTPRB,C1orf54,FRMPD1,CNKSR2,KANSL3,IZUMO4,BEX1,ATP10B,ST5,AJAP1,VAMP1,CHST5,TRPM2,XRCC4" Drug 6018_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "BIN1,APOC1,APP,PLA2G4C,CFLAR,NEURL1,CDH8,SRSF11,VCAN,PDE4DIP,RIMS2,CYBB,DMPK,HS3ST2,HIPK3,C3orf18,VPS13B,TBC1D16,TUBB4A,BAIAP2,GAP43,SRCAP,GFER,GPR75,GNAL,PCLO,GRIK2,ADAMTS8,NR3C1,IL1RAPL1,HRH3,KLF12,ICA1,KCND3,VWA5A,ZNF862,PPP1R1A,MAPK8,PTHLH,RAB3A,SEMA6D,SBF1,PPP4R3A,RBM34,ZCCHC24,ASTN2,TAL1,KIAA0930,ZEB1,RPGRIP1L,KAT6B,PIK3R5,TUBB1,VGF,LAT2,ZNF74,NT5M,KAT6A" Drug 3970_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ASIC1,GAS7,APOC1,CDK10,PDE8B,BRINP2,CBFA2T2,TAOK2,ZFYVE9,CLTB,SLC4A7,CSF1,RIMS2,PPP6R2,DCAF4,RUSC2,DRD1,EDNRA,FEM1B,EFNB3,EGFR,RASGRP2,F5,TRMO,DLL3,GAD1,RND1,GPER1,EML4,GRIK5,CACFD1,INPP5B,KCNJ5,KCNMA1,KCNN2,KCNQ3,VWA5A,BCO1,NF1,CLDN11,SERPINE2,PLCD1,PTPRD,RPS6KA2,SEMA6D,PEG10,ZC3H13,TROVE2,EXOC7,TCF7L2,CRTC1,FAM155A,VIPR2,ZFP37,ITM2C,MPPE1,PLSCR4,ADAMTSL3" Drug 3349_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "NDRG2,NME5,CDC42BPA,APOC1,RGS20,ARHGEF7,BTRC,CFAP410,CALB2,CHN2,CHRNB2,LHX2,STOML1,FAM149A,NECTIN3,CNTNAP2,RIMS2,EXOG,DTNA,ST8SIA3,EFNB3,MBNL2,FAM198B,KIAA1109,FHL1,GAD1,ALDH1L1,PCDH17,RND1,GLYR1,GNAO1,ADAMTS13,GSN,NXPH3,DHX35,TJAP1,LIFR,MGAT3,CNOT4,NTRK2,PDE3B,MAPK8,ZMAT4,TRIM68,RASA3,ELMO2,SNCA,CLSTN2,MAPK8IP3,SLC19A3,ARHGEF12,THRA,HEY2,TMOD1,CABIN1,TRIO,TRPM2,ITM2C" Drug 4750_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "RALGAPA1,ASIC1,ADORA1,ADGRF5,SEMA7A,CDK13,CFAP410,ARHGEF1,CHGA,VAX2,DNAJB5,CPS1,AATK,SNCAIP,DRP2,DTNB,EDN3,PLXNC1,C3orf18,RASGRP2,ERCC2,IGSF6,CEND1,FGFR1,FHL1,CAMKK2,OGA,FYB1,ALDH1L1,SRCAP,GPR75,GNAL,GPM6B,PCLO,GRM7,TJAP1,ADAM22,MYH6,MYT1,P2RY1,PALM,PLCB2,PLTP,MAPK7,PTHLH,C1orf54,TCP11L1,RYR1,PPP1R9A,ASAP3,CNKSR2,KIF21B,SPART,EPB41L3,MAPK8IP3,THRA,SEZ6L,PRDM2" Drug 3390_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ARID1A,AK2,LTBP4,BIN1,SEMA7A,CNTNAP1,APC,APP,ASPH,CFAP410,STOML1,PDE4DIP,PHF14,DCAF4,NOS1AP,TOM1,EFNB3,NCALD,SCML2,FER,FGFR1,BAIAP2,PDLIM5,SRCAP,GLYR1,TDRKH,GSN,AGFG1,KCNH2,VWA5A,SMAD1,MMP16,ADAM22,NOS1,ODF2,PALM,NLE1,PLCD1,STRN3,LRP12,ELOVL2,PEX5,SBF1,PPP1R9A,FUZ,FNDC3A,PPP4R3A,PKNOX2,BTBD7,SNCA,DIP2A,DICER1,AP4E1,TPM2,TRIO,ZNF24,REEP1,EPM2A" Drug 4407_UP Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "C1QTNF1,BEGAIN,ANK1,ARHGDIG,AZGP1,CACNA1I,CACNA1D,RHBDL1,GPR37L1,TAOK2,NRG2,PLCH2,CNTNAP2,RIMS2,RIMS3,TMCC2,DTNB,EDN1,SGK2,EPHB1,FAM198B,TUBB4A,KIAA1109,FGFR1,FUT9,GPR162,KCND3,KCNH1,LSS,ADAM22,MSR1,NTRK2,OGG1,OMG,OPCML,GPR85,PENK,C19orf57,PRKCB,MAPK8,SAMD9,RFX2,RGS12,SH3GL3,CPEB3,BCAN,SLC2A5,SLC11A1,OGDHL,LIMCH1,ZCCHC24,ERC1,NPAS3,PLCB1,WSCD1,TK2,HEY2,UCHL1" Drug 5461_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ACTN2,ADRA1B,PLA2G6,ALCAM,RGS20,BAIAP3,LDLRAD4,SLC16A4,CACNA2D2,ARHGEF4,RIMS2,DCAF4,RIMS3,DBN1,DTNA,ING4,MRNIP,C3orf18,SPEG,ZNF589,FGFR1,HPCAL4,FOXG1,DKK3,HBS1L,NEU3,GFER,HPGDS,GLYR1,GRM1,ATXN2L,ICA1,MAP4,ADAM22,NF1,MINDY2,MAPK7,PTPRD,PTPRO,RAB5B,RGS12,CCDC25,FBXW7,WLS,SALL1,ST6GAL1,ANKRD6,FAM214B,ARHGEF40,ZCCHC24,ZHX3,ZSWIM8,KDM4C,VAMP1,ZIC3,SYNC,WNK1,HPS4" Drug 4314_DN Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "AK2,LGR5,ATM,SLC4A4,NRG2,CRMP1,ABCG1,AATK,VCAN,C2CD2L,SRGAP3,TMCC2,DTNA,LPAR6,ING4,EPHA5,CDKL3,ETV1,FGF1,GABRA2,MSL3,GSTM5,GUCY1B1,ELOVL5,SCIN,IL6ST,INPP5B,AFF1,MMP16,TAGLN3,NDP,PAK3,PC,PDGFRA,ZNF426,PRPH,TMEM104,WDR25,PTHLH,C1orf54,BEND5,DCUN1D2,GSTCD,IL17RB,SFPQ,ZNF415,DOP1A,DOK5,BEX1,MAPK8IP3,TCF4,PSD3,TRIO,VIPR2,PARP6,KCNAB1,KAT6A,DPF3" Drug 7251_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "C1QTNF1,MRTFA,ARRB2,MARCH3,SLC4A4,KSR1,CDK5R1,MYRF,RUNX1T1,CD86,CDH10,CRLF1,CNOT8,NRXN3,CTNND2,RUSC2,KBTBD11,AASS,EPB41L1,EFEMP1,FGF13,FLT1,TRMO,OGA,C1QL1,GLI2,POLL,MAN1B1,TJAP1,DIPK1A,KIF2A,KIFC3,ADAM11,PFKFB2,PIK3C2A,MAPK7,WDR25,ZSCAN2,SBF1,DOCK10,PPP4R3A,FAM214B,TMCC1,ZBTB43,SS18,MAPK8IP3,SEPT8,CEP68,GSE1,SYT1,SZT2,TF,TRPC1,HIRA,WNT7A,ZNF711,EMSY,EPM2A" Drug 3776_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "EPB41L5,CDC14B,SEMA4G,ADAM23,CBS,ARHGEF1,CBFA2T2,NEURL1,LARGE1,TAOK2,ARHGAP22,RAB28,LY86,PICK1,HAPLN1,PHF14,CTNND2,RIMS3,MFAP3L,EXOG,FEM1B,PLEKHO1,STX2,FGFR1,DCTN2,ATP8A2,SRCAP,POLL,IL12A,VWA5A,MAPT,ZNF862,NDP,NF1,CNOT4,PALM,POLG,PRKAR1B,CNTLN,ACSS3,C1orf54,TMEM206,NEK11,TCP11L1,KCNIP1,ATXN7,ASAP3,FUZ,RPH3A,ATP10B,COLGALT2,PSD3,HIRA,VGF,LMF1,XRCC4,SPHK2,DPF3" Drug 4685_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "AMT,PPFIA4,APOC1,SLC4A4,FUBP1,CACNA1G,LDLRAD4,CRLF1,NRXN3,ABCG2,SH2B1,PDE4DIP,BRINP1,MFAP3L,SMG7,RABGAP1L,EDN1,SGK2,EIF4G2,ING4,MTSS1L,FAM198B,ST3GAL6,GABRA2,SRCAP,KCNMB4,GNG3,GPM6B,GUCY1A2,IGFBP1,TJAP1,MDFI,MMP16,NF1,PDE4B,PTHLH,ZSCAN32,TMEM231,RGS4,SH3GL2,FRMPD1,DZIP1,SLC1A7,BTBD7,SNCA,SOX2,LHPP,SZT2,DOCK9,AP4E1,TIMP4,TNS1,RPRM,SF1,SEMA3B,MPPE1,FAM13C,KAT6A" Drug 3971_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ADORA1,AGT,GAS7,ARSE,PDE8B,CACNA2D1,CD86,STOML1,FADS2,DNAJB5,WHRN,CSF1,RIPOR2,DGKG,ERCC2,REEP2,CAMSAP1,FLNC,GAP43,SIGLEC8,GDF9,GRM8,IRAK3,IFI16,SHISAL1,KCNMA1,KCNN1,MEF2C,ADAM22,MYO7A,FXYD7,NOVA2,NTRK2,NTRK3,PROX1,ACSM5,C1orf54,BEND5,KHDRBS2,CRTAC1,SCN8A,CNKSR2,ST8SIA1,SLC1A7,IZUMO4,HECW1,CDK19,NPAS3,SYT11,TAL1,TCF4,DAAM2,CHST5,AMOT,LAT2,ZNF154,FAM13C,NUP214" Drug 6367_DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "TKTL1,ADORA2A,AP2A2,C1QTNF1,CNTNAP1,APBB2,B3GALT2,CADM3,MYRF,CFAP410,SLC16A4,SCARB1,CDH2,QKI,COL9A1,RASSF2,RCAN1,EDNRA,HEYL,MBNL2,PLXNC1,VPS13B,EXTL1,CAMSAP1,FOXG1,KHDRBS3,TMEM8B,CPLX2,GPM6A,GPM6B,GRIK1,NR3C1,MGAT3,MOBP,ADAM22,NNAT,NPPA,MAPK7,PTHLH,PTPRN,RPS6KA2,SCN2B,NLGN1,LIMS2,CCDC88A,CXXC4,LIMCH1,RBM34,ARHGAP26,CLSTN2,AJAP1,ACSBG1,VAMP1,ZEB1,SYNE1,DOCK9,CLIP2,STMN4" Drug 6465_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "AP2A2,APBA2,GAS7,ATP1A2,SLC4A4,N4BP2L1,SGCE,CAMK2B,HIP1R,CHRNB2,SLC22A6,QKI,SULT4A1,WHRN,COL9A3,HAPLN1,TENM4,OSBPL3,DCAF4,SPOCK2,USH1C,SGK2,ZNF589,FER,FOXG1,C1orf61,AGAP2,AFF2,SORBS1,GABRA2,GAD1,SIGLEC8,GRM3,HRH3,HLF,KCND3,KCNJ5,KCNN1,CNOT4,OPCML,NLE1,LRP12,RELN,SAMD9,C1orf54,CCDC25,RPS6KA2,ASAP3,SNCA,PDZD2,ZCCHC24,SPP1,WWC1,TRIM2,TLR4,PRMT8,WNK1,KCNAB1" Drug 7378_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ADCY6,PLA2G6,ALAD,CDC14B,NRP2,CDK5R1,MTMR3,CACNA1A,CAST,FOXN3,CPS1,AKAP12,AATK,CTIF,RUSC2,SPOCK3,ST8SIA3,EFNA3,EGFR,MRNIP,PLEKHO1,PIPOX,RRAGB,GABRA2,GAD2,RUNDC3A,GPM6A,KLF12,DHX35,IL6R,LSS,CLDN11,PALM,MAPK7,BCAS3,GDPD2,PLPPR1,PTPRE,SUPT20H,CNKSR2,SLC1A7,SLC8A1,TNIK,ZHX3,CAND2,DDN,SAMSN1,ARC,SYN2,KAZN,ADGRL3,OBSL1,CABIN1,AMACR,TRO,SEMA3B,UBE3B,NUP214" Drug 5801_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ASIC1,ADRA1D,CDK10,BRINP2,CADM3,ADAM23,MTMR3,BAIAP3,RUNX1T1,SYNGR3,FOXN3,PLAA,CLCN4,RAB26,SPOCK2,DTNA,DYRK1A,EDIL3,AASS,ING4,GAD2,SYT17,GFER,GPM6A,GRM1,GRM7,SHISAL1,KCNB1,KCNF1,KCNJ3,KCNJ4,LSS,MGAT3,NPTX1,PDE3B,ENPP2,GPR85,PPARA,LRRN3,PRKCB,ENOX1,OGDHL,SCN3B,TSNAXIP1,ZSWIM8,HECW1,RBM26,VAMP1,ZFPM2,CHST5,KCNE5,TMPRSS5,TUBB1,VSNL1,REEP1,STMN4,ADAMTS9,SLC17A7" Drug 3572_UP Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "NDRG2,ADRA1D,SYT13,CDC42BPA,APLP1,BCAS1,CA4,DLGAP2,CHM,ARHGEF6,CRYM,FAM169A,NOS1AP,ATN1,SIDT2,EFNA3,EIF4G2,TENM1,STX2,OLFM1,GPR153,GAD1,TMEM8B,SIGLEC8,NEU3,LYVE1,RUNDC3A,RND1,ITGAM,MAOB,ADAM11,BCO1,CNOT4,OPCML,PENK,PFKFB2,PLCD1,POU3F2,ZSCAN32,PPP1R9A,RPH3A,FAM214B,KANSL3,PKNOX2,KDM4B,WDTC1,NMNAT2,THSD1,CRTC1,AHCYL2,ICAM5,PARD3,TNS1,PIK3R5,VGF,KCNAB1,SENP7,JPH3" Drug 3739_DN Foliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ALK,APP,RIPK1,MYRF,CACNA1A,NRG2,SH2B1,CREB5,AATK,MICAL2,CSNK1E,ARHGEF4,DAPK3,PARD6A,SPOCK3,PLXNC1,ELAVL3,STX2,CDKL3,FGF1,FOXG1,CGREF1,RAB30,KCNMB4,GRIK2,GRIK5,GUCY1B1,KCNJ5,LMO2,VWA5A,MOBP,MT1M,PCBP3,NUMA1,PIK3CD,PIK3R1,MINDY2,PLPPR1,GAL3ST4,TCP11L1,IL17RB,SELL,ASAP3,AMBRA1,SLN,ZNF415,IQSEC2,THSD1,MAPK8IP3,SYN2,TBCEL,DOCK9,TIAM1,UBE2H,KLC2,TRIM9,NT5M,GAN" Drug 2058_UP Nicergoline; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "MTUS1,NME5,ADGRF5,APP,SOCS6,NMT2,HOMER3,ARMC8,ABI3BP,PDE4DIP,PPP6R2,USP6NL,ING4,F3,FER,FOXG1,ANKFY1,ERAP1,SRCAP,GLYR1,GPR17,GPR19,STON1,GPER1,CACFD1,FICD,IFI16,SHISAL1,KIF5C,KIFC3,NAP1L3,SAMD9,PTPRE,RAD52,SH3TC2,RGS4,SUGCT,AP1AR,TRA2B,ZFP30,PPP1R9A,SLC20A2,KDM4B,SAMSN1,SS18,TBL1X,TCF4,DOCK9,PSD3,ARHGEF12,CRTC1,ZNF34,HEY1,KAT6B,WIPF1,NSD2,EMSY,LRP8" Drug 4361_UP Flutamide [13311-84-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "LTBP4,APC,AQP6,ASPH,CHRD,N4BP2L1,CACNA1G,NEURL1,CDH2,CDH8,DLGAP1,SIPA1L1,VCAN,DGKG,DAPK1,SPOCK2,CTIF,DBT,RCAN1,AASS,ELAVL3,RASGRP2,ERBB2,FGF12,EFCAB2,SIGLEC8,RUNDC3A,GRIK5,GRM1,KCNA4,KCNJ5,KCNMA1,KCNN1,NPY,NOVA2,OMG,PLCD1,PRKCB,RELN,GAL3ST4,RNASE1,TMEM206,SYNDIG1,DOCK10,SLC11A1,HECW1,ATP10B,TAL1,RPGRIP1L,FAM189A1,HEY1,PARD3,TRPC1,UCHL1,BEST1,WIPF1,LAT2,ZNF24" Drug 5527_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ALK,BEGAIN,BIN1,AMT,APC,SEMA4G,ARHGDIG,PLA2G4C,CDK13,SYNJ1,BTRC,SLC16A4,CDR1,FEZ1,VCAN,EDRF1,SEC14L5,SPOCK2,MFAP3L,ECM2,EDIL3,SNX29,SIDT2,MBNL2,CDKL3,F5,TOX3,ADAMTS13,GUCY1A2,PTGDR2,IL11RA,IPO5,VWA5A,MARK1,MBD1,NUCB1,P2RY1,KCNK10,TREM2,SNTG1,SERPINI1,CNNM2,PLPPR1,ELOVL2,TCP11L1,SYBU,URGCP,SHANK2,CXXC4,ZBTB43,PHLDB1,DICER1,TK2,HIRA,SLC30A3,EMSY,NUP214,JPH3" Drug 3369_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "TKTL1,ACTN2,NDRG2,ADCY2,AP2A2,TRMT9B,APAF1,APBB2,GAS7,ATP1A3,LDLRAD4,CACNA2D1,SEPT7,CDH8,ZFYVE9,SULT4A1,BRINP1,MAGI2,TMCC2,DYRK1A,HSD17B14,ERCC2,CEND1,AFF2,KHDRBS3,GAD1,NEU3,C1QL1,GPER1,GRB10,GRIK5,TJAP1,ITIH2,KCNH2,KCNQ3,LSS,ADAM22,PDE1C,PIK3CD,CEP41,PTAFR,CCDC40,ZDHHC14,SLC6A9,SHANK2,SLCO1A2,IGSF9B,SYN2,WSCD1,CRTC1,DAAM2,PARD3,TNS1,LILRA4,TRPM2,SLC17A7,KCNAB1,PLSCR4" Drug 3729_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "SYN3,MTUS1,BEGAIN,APBB1,APP,ALDH4A1,SLC2A11,BAIAP3,CFAP410,RUNX1T1,CNOT8,RAB28,CLCN4,DNAJB5,SULT4A1,RAB26,RIMS2,DLG4,DRP2,DYRK1A,EDNRA,FCF1,EPHA5,EPHB1,NCALD,KIAA1109,OLFM1,GPR19,GRM1,MIA2,MMP16,PBX1,PDE4D,PFKFB4,MTRF1L,STRN3,POU3F2,MAPK8,WDR25,ATG16L1,RGS4,RIT2,PEX26,ARHGEF40,KIF21B,HECW1,CDK19,DDN,NFASC,ZEB1,CRTC1,KAT6B,TRIO,XRCC4,PRDM2,MVB12B,KAT6A,PHTF2" Drug 5999_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ADCY2,AMPH,KCNAB2,SEMA4G,ASCL1,CFAP410,CACNA1D,CDH10,DNAJB5,CRMP1,HAPLN1,DMPK,EDNRA,EGFR,ANKMY1,FOXG1,FLT1,PDLIM5,NSG1,FYB1,GABRA5,HBS1L,GAP43,ALDH1L1,MALT1,GNG4,CNTRL,IRF8,KCNH2,KCNJ3,LIG4,ADAM11,ADAM22,MSR1,MX1,PDE3B,PPARA,PPP2R2B,RASGRF1,ZDHHC14,RORB,WLS,KCNIP2,KCNIP1,RYR1,SEMA6D,SCN8A,SH3BP2,SLC11A1,SMARCD3,DOK5,SSTR2,DOCK9,TMOD1,UBE3A,PRDM2,PAK5,NUP214" Drug 4114_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "SEMA6A,AQP4,CDK13,CCDC181,KSR1,BAIAP3,CAMK2B,NEURL1,CDH10,ZFYVE9,SULT4A1,WHRN,DAPK3,CTIF,DMD,ATN1,GNE,EDIL3,EFNB3,ELAVL2,MTSS1L,B3GAT1,GAB1,GABRA2,GPM6A,ATXN2L,HMGCR,ICA1,KCNN1,LSS,AFDN,MOBP,NF1,NOS1,OPCML,TREM2,PALM,RETREG1,PLCD1,SLC25A23,GDPD2,C1orf54,SCN8A,SUPT20H,SH3BP2,ASAP3,CNKSR2,SLC1A7,SNCA,KIF13A,ZNF415,JMJD6,ICAM5,TMOD1,TRPC3,ZIC3,SLC17A7,AP3B2" Drug 3903_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.77E-07 3.32E-02 1.87E-05 2.13E-04 58 196 "ASIC1,TKTL1,NDRG2,TRMT9B,AMPD3,APAF1,MARK4,SLC4A4,CACNA1D,RUNX1T1,GPR37L1,RCBTB2,ARHGEF6,AKAP7,WHRN,NCOR2,PLCH2,CNTNAP2,RUSC2,C3orf18,EN2,F5,TUBB4A,FGFR1,FGFR3,CAMSAP1,FHL1,CAMKK2,GAB1,SPACA9,HLF,HTR2A,IFI16,IGF1,TJAP1,KCNN2,KPNA5,MX1,PFKFB2,EPN1,PURG,MARCH1,KLHDC8A,EMID1,ZFP2,SLC1A3,RIMS1,SOX2,IZUMO4,ARHGAP26,ACSBG1,ABCC8,SYN2,CUX2,AMOT,VAV2,VIPR2,PRDM2" Drug 4483_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.86E-07 3.36E-02 1.89E-05 2.16E-04 54 178 "DPF1,ABAT,ASPHD1,MARK4,ST3GAL5,USP2,CHN2,NRXN3,WHRN,ABCG1,ARHGEF10,PDE4DIP,CTH,KIAA0513,C2CD2L,PTK2B,TUBB4A,TAOK3,BAIAP2,SORBS1,PDLIM5,FYN,ZNF44,GUCY1B1,ITGA7,KCND3,KIF5C,LIFR,LSS,MAP2,MAPT,NRGN,PCDH9,SERPINI1,PIK3CD,RETREG1,PTPRH,ENOX1,RGS4,TTLL7,FAM102A,SH3GL3,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT11,SYT1,KIAA0930,TNS1,CADM1,DNAJC12,SLC17A7" Drug CID000003837 AC1L1GTT Stitch 6.91E-07 3.39E-02 1.91E-05 2.17E-04 66 233 "AGT,ATP2B1,CFLAR,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,KRIT1,LRBA,SLC22A6,CHD1L,MYEF2,EDN1,PPP1R1B,CAMKK2,PPARGC1A,GRB10,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,GRM3,HMGB1,HTR2A,MYLK2,JAK2,KCNC1,KCND2,KCND3,KCNJ4,KCNK3,MBP,MEF2C,MYBPC1,NEFM,P2RX7,P2RY1,CAMKV,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,PTK2,PTPRN2,RGS4,KCNIP2,RYR1,RYR3,SNAP25,SYN2,TIAM1,CABIN1,SLC13A3,CAMK1G,NUP214" Drug CID000059708 etiracetam Stitch 7.24E-07 3.55E-02 2.00E-05 2.27E-04 26 62 "ABAT,ADORA2A,AMPH,PROM1,CACNA1G,CBS,CREM,CST3,SV2B,SV2A,GPHN,GAD1,GAD2,GFAP,GLRB,POLL,GRIA1,GRIA2,GRIA4,GRM3,GRM8,MEST,ABCB1,SLC6A11,ICAM5,EPM2A" Drug ctd:D005680 gamma-Aminobutyric Acid CTD 7.24E-07 3.55E-02 2.00E-05 2.27E-04 26 62 "ABAT,AGT,DRD1,FGF1,FGF13,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GFAP,KCNJ3,NCAM1,HCN1,PPARA,KCNIP1,SLC6A1,SLC6A11,SYN2" Drug ctd:D008731 Methoxychlor CTD 7.26E-07 3.56E-02 2.00E-05 2.27E-04 130 551 "ADRA1B,ADRB2,CASKIN1,AK2,BEGAIN,AMH,AMPH,BIN1,OGT,CNTNAP1,DGKZ,ARRB1,NCOA1,ATP1A2,ATP2A2,BID,KSR1,WASF1,CACNA1A,CACNB2,HAP1,ARHGEF1,SCARB1,CDC25B,NUMBL,FOXN3,CHGA,CHRNA4,CLU,QKI,AKAP5,CP,NCOR1,SDC3,DAPK1,SIRPA,MAGI2,DLG3,DLG4,SHANK1,DPP6,DRD1,DNM1L,EDN1,EGFR,EGR3,SORBS3,ELAVL2,GPHN,DLC1,FOXO3,DCTN2,CAMKK2,FYN,GABRA5,GALR1,GHR,STARD3,GNAO1,GNAS,GRIA2,GRIN1,NR3C1,GRM3,PTPN5,HSD17B1,HSP90AA1,HTR5A,IGF1,IL6R,ITGAM,JAK1,KCNA2,KCNA4,KCNB1,KCNC1,KCNC2,KCNMA1,KCNN2,KIF5A,KLC1,MAG,MBP,MEST,NFIA,NFIX,NTRK2,NUCB2,OPRL1,OXTR,P2RY1,PAK3,PDE2A,PDYN,PHKG1,PIK3R1,MED1,PRKCB,MAPK3,MAPK8,MAPK10,PTPRG,PTPRN,PTPRN2,RALGDS,MEG3,STX1B,SCN2A,TNFRSF19,SFPQ,MRAS,ITSN1,PPP1R9A,SLC1A2,SLC1A6,SLC8A2,SLC15A2,SNRPN,KIF1B,SSTR2,MAPK8IP3,STXBP1,SYT4,TAC1,TAC3,ACSL6,SIN3B,TRH,KCNAB1,SLC17A6" Drug 1240_UP 2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.49E-07 3.67E-02 2.06E-05 2.34E-04 57 192 "ASIC1,ABHD6,APC,STX16,N4BP2L1,ST3GAL5,CACNA2D2,CHN2,CHRNB2,ARMC8,AKAP5,SLITRK5,SPOCK2,DNAJC6,PLPPR4,RABGAP1L,EDIL3,PLEKHO1,FYN,GAD1,GNG3,STON1,GUCY1B1,DIPK1A,ITGA7,MDFI,ZNF862,RETREG1,POLG,PRPH,PTAFR,RAB3IL1,RGS4,NUDT11,ROM1,TCP11L1,ITSN1,PREX2,SLC6A9,ARHGEF40,TNIK,TSNAXIP1,SAMSN1,MAPK8IP3,RGL1,SYT1,COBL,KAZN,TCF4,GPR161,THRA,HEY1,TK2,AMACR,DNAJC12,LAT2,PHTF2" Drug 2450_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 7.49E-07 3.67E-02 2.06E-05 2.34E-04 57 192 "NDRG3,MTUS1,BEGAIN,APBB2,STX16,MPDZ,GYG2,HIP1R,CHM,DNAJB5,RAB26,CNTN1,CRMP1,CSF1,PDE4DIP,FAM131B,DOCK4,KIAA0513,DBT,DNAJC6,CNIH3,MAMLD1,ETV1,TLR7,PTK2B,ATP8A1,BAIAP2,TRAF3IP2,SIGLEC8,STON1,IFI16,KCND1,KCNH2,MAP4,MEF2C,AFF1,MYBPC1,NCAM1,PCDH9,DUSP26,PLCL1,PLP1,RPS20,SLC1A3,MAPK8IP3,VAMP1,DNMBP,CAMSAP2,WWC1,RPGRIP1L,PSD3,TEX15,ATP13A2,AP4E1,RBFOX2,LMF1,FZD3" Drug 7382_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.49E-07 3.67E-02 2.06E-05 2.34E-04 57 192 "ALAD,AMT,CDC42BPA,GAS7,SHROOM2,PDE8B,ATP1A2,CADM3,KIF1A,NRP2,LDLRAD4,AP4M1,TAOK2,PLAA,PDE4DIP,SNPH,DAPK3,MFAP3L,RUSC2,MAGI2,FCF1,COQ7,LRRC23,DENND4A,ETV1,ATP8A1,FER,FGFR3,AFF2,GCNT2,CYP46A1,ICA1,MT1M,TAGLN3,MX1,PPARA,SAMD9,WDR25,PTPRE,PTPRH,SH3TC2,ATG16L1,ZCWPW1,MAPK12,FUZ,ANKRD6,SLC4A3,SPTAN1,POGZ,PHLDB1,ACSBG1,KLHL4,AHCYL2,TRPC1,REEP1,KCNAB1,NUP214" Drug 7179_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.54E-07 3.70E-02 2.07E-05 2.36E-04 53 174 "ABHD6,ADD3,NME5,ARNTL,BMP7,ST3GAL5,RAB29,CLGN,AKAP12,PDE4DIP,RIMS3,ARMCX2,DNAJC6,JAKMIP2,EFNA3,EFNB3,MBNL2,CDKL3,BAIAP2,DPYSL4,FYN,CYP46A1,STON1,KIF5C,MXI1,NEK1,PCDH9,SERPINI1,PIK3CD,PKIA,PRPH,SEC14L1,SH3BGR,SH3GL3,SYBU,WDR47,CCDC88A,ZCCHC24,THSD1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,AGTPBP1,HEY1,NPL,RUNDC3B,SSBP2,DNAJC12,NAV2,SLC17A7" Drug 5981_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.56E-07 3.71E-02 2.08E-05 2.36E-04 55 183 "ABAT,ADRB2,CDC14B,ARNTL,BRINP2,ST3GAL5,HIP1R,USP2,NMT2,ABCG1,PDE4DIP,CTH,CTNND2,PLPPR4,SRGAP3,EDNRA,EFNA3,RASGRP2,PTK2B,TUBB4A,TAOK3,BAIAP2,C1QL1,RND1,GLS,GNAO1,STON1,GUCY1B1,KCNH2,KIF5C,LIFR,MATN3,CDK18,SERPINI1,RETREG1,PLCD1,SPATA6,PRPH,RAB3A,RASGRF1,FAM102A,SH3GL3,AMBRA1,KIF21B,SOX15,ELOVL4,RGL1,ACSBG1,SYT11,ARC,SYT1,RUNDC3B,CADM1,DNAJC12,TRIM9" Drug CID000002519 caffeine Stitch 7.74E-07 3.80E-02 2.13E-05 2.42E-04 132 562 "ADCY2,ADCY5,ADCY6,ADCY8,CDC7,ADORA1,ADORA2A,ADORA3,PDXK,PDE8B,ATM,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CH25H,BRSK2,CCK,KRIT1,P2RX6,LRBA,CACNA2D2,CHRM1,CHRNA4,CHRNB2,CNOT8,AKAP6,COX4I1,PNKD,PHF14,PLCXD3,DMD,DRD1,CACNG7,LPAR6,EIF1,ENPP6,ERCC2,CACNG3,CACNG2,PPP1R1B,ATP2C1,BRSK1,MSTN,GPR162,CYP46A1,KCNMB4,LPAR4,GRIA1,GRIA2,GRIA4,PLCD4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,MYLK2,IGFBP1,KCNH2,KCNMA1,MAG,MARK1,N6AMT1,MYBPC1,MYH6,P2RY13,NODAL,P2RX7,P2RY1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PIK3C2A,PKD1,XRN1,PLCB2,PLCD1,PTPA,PRKACB,GDPD2,PYGM,QDPR,SEC61A2,NEK11,RYR1,RYR3,MAPK12,SMPD3,ASIC4,SLC4A3,PPP4R3A,TMEM132D,NEK4,PLCB1,TPCN2,SYNE1,TK2,TRH,TRPC1,DNAJC12,P2RY12,ZNF24" Drug 4497_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "DPF1,SYN3,ALK,AMH,GAS7,ATP1A3,CFLAR,GYG2,TAOK2,ARHGAP22,SULT4A1,ABCG1,ERC2,EDRF1,PYGO1,CTIF,MYEF2,ATN1,DSCAM,SEMA3D,EFNB3,TNK2,OLIG2,ATP8A1,ST3GAL6,C1orf61,ATP8A2,GNAO1,GRIK5,CACFD1,FAM107A,HTR2A,ICA1,MARK1,MBP,MT1M,SLCO1C1,P2RY1,ENPP2,PFKFB2,PFKFB4,STRN3,GDPD2,PTPRH,ZSCAN2,FBXW7,RPS20,SH3BP2,SLC11A1,HECW1,ADGRL3,PCDHGA10,PIK3R5,FLRT2,SPHK2,REEP1,NAV2,PARP11" Drug 4240_UP Letrozole [112809-51-5]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ACTN2,NDRG2,ADCY2,PKP4,PRX,ZSCAN18,ATP6V0A1,ADGRB3,BMP7,RUNX1T1,CNTN1,PDE4DIP,PHF14,RIMS3,DCC,SRGAP3,NCALD,ABCA8,CAMSAP1,TRMO,HBS1L,SYT17,NEU3,SRCAP,PCDH17,LILRA2,GRIK5,ATXN2L,KIT,SMAD1,MAN2A2,MARK1,MMP16,NF1,NOS1,NRCAM,NTRK2,OLR1,PDPK1,MINDY2,MARCH1,ZMAT4,TMEM206,SCN2A,FBXO11,ZNF334,SNCA,FAIM2,TNIK,ZHX3,SPP1,SPTB,LMO3,SYN2,ASTN2,TAL1,KCNAB1,PHTF2" Drug 543_UP "1,5-Isoquinolinediol; Up 200; 100uM; HL60; HG-U133A" Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,AP2A2,ANK2,APBB2,CDK10,RASL11B,CADM3,N4BP2L1,ST3GAL5,KYAT1,FOXN3,CHN2,ZFYVE9,FAM189A2,TMEM184B,CRMP1,RIMS2,SPOCK2,DCT,C2CD2L,DTNA,SIDT2,ING4,IGSF6,TESK2,ZNF589,BAIAP2,CAP2,FYN,GOLGB1,CACFD1,PRDM5,NXPH3,HMX1,JAK2,MBD1,NOS1,PAK3,SSH1,CEP41,PRPH,GAL3ST4,TRIM68,RGS12,RLBP1,STUM,SH3BP2,SLN,ZCCHC24,TSNAXIP1,ZSWIM8,CDK19,SRPK2,VAMP1,TMPRSS5,RNF103,KCNAB1,DPF3" Drug 3818_UP U-62066 [87151-85-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADGRF5,SPARCL1,FAM135A,AQP4,CDC14B,ARHGDIG,CDK13,N4BP2L1,NRP2,LDLRAD4,RUNX1T1,JAM2,PLCH2,SMG7,AK5,EDN3,FRY,EFNA3,ZNF391,PDLIM5,B3GAT1,FYB1,DKK3,TMEM8B,LILRA2,KCNC1,MATK,MGAT3,KITLG,P2RY13,NF1,NOVA2,NPTX1,OPCML,P2RY1,SNTG1,PFKFB4,PRRX1,C19orf57,PPARA,PROX1,GAL3ST4,ZMAT4,RGS3,RGS12,PBRM1,EMID1,FAM214B,SLN,SOX2,SSTR2,DOCK9,TPM3,HIRA,CADM1,UCHL1,FLRT2,NUP214" Drug 3681_UP Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "SEMA7A,ATP2B2,CACNA1I,CFAP410,CHN2,CHRNA4,JAM2,CSF1R,ARHGAP24,RIMS3,ARMCX2,SV2B,ARNT2,USH1C,FCF1,ELAVL4,RGS17,IGSF6,F5,KIAA1109,CAMSAP1,SEMA4D,B3GAT1,GAB1,GABRB3,GRIK1,GRM1,GRM2,KCNH2,KCNJ5,KIFC3,LAMA2,NELL2,NF1,NUMA1,PDGFRA,MINDY2,PTAFR,PTN,PTPRD,MYH14,NTNG1,HKDC1,SLC1A6,SCN3B,DDN,ATP10B,SYT1,PCDHGA1,CRTC1,TNS1,LAT2,SPHK2,ZNF154,LAMP5,SEMA3B,KCNAB1,NLRP3" Drug 4100_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "DPF1,ALAD,ANK2,APC,APP,ZSCAN18,SLC4A4,BCHE,CAMK2B,CAPN3,NEURL1,RAB33A,STOML1,AKAP5,HAPLN1,ARHGEF4,PYGO1,C2CD2L,SPOCK3,SV2A,DSCAM,DTNA,EDIL3,ETV1,KAT8,HPCAL4,AGAP2,GART,NEU3,GNG4,GPD2,GSTM5,ATXN2L,HTR5A,LIG4,KITLG,ADAM22,LYRM9,SLCO1C1,NTRK2,DDR2,SERPINI1,PLCD1,NECAB2,MAPK8,PTPRB,RAB3A,FOXRED2,SCN2B,NTNG1,HECW1,TROVE2,SS18,COBL,SLC19A3,CRTC1,KCNAB1,RNF146" Drug 4231_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "SYN3,ASIC1,ACTN2,ARID1A,ADORA1,NR0B1,APC,AQP4,DDX3Y,ATP2B3,ADAM23,CACNG1,CALB2,NRXN3,CALY,NOS1AP,SNX29,RASGRP2,EPHB1,PIPOX,FGFR1,CAMSAP1,AFF2,EFCAB2,NSG1,GABRA3,PCDH17,HPSE2,ICA1,IGSF1,PACRG,MAP2,AFDN,MMP16,ADAM22,NCAM1,NOS1,PBX1,PDE4D,MAPK10,PTPRD,ACSS3,RASGRF1,SLC6A15,RGS4,KCNIP2,MAST1,ZNF415,NFASC,PHLDB1,ACSBG1,ADGRL3,SZT2,TMOD1,ZNF24,ZNF154,SLC17A7,MVB12B" Drug 3529_DN Lansoprazole [103577-45-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "KIDINS220,AK2,PLA2G6,BIN1,CDC42BPA,PDE8B,MARK4,CFLAR,NEURL1,B4GALT6,QKI,SULT4A1,ABI3BP,SH2B1,CRY2,DZIP3,RUSC2,DTNA,EDNRA,EFNB3,MBNL2,IRAK4,LRRC23,FLNC,GAB1,TRAF3IP2,DISC1,CNTRL,GRIK5,HNMT,HSD17B1,INPP5B,JAK2,TM6SF1,MID1,GIT1,LYRM9,NNAT,NPR2,NUMA1,OPCML,PALM,SERPINE2,PLXNB1,RAB3A,CCDC25,ROM1,SEMA6D,SIRT2,CHST8,ZNF34,PARD3,CDK20,SPHK2,WNK1,NAV2,RNF170,SSPN" Drug 2795_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "RALGAPA1,ALK,MRTFA,DOC2A,APLP1,PLA2G4C,ASPH,BRINP2,BACH1,GYG2,CACNA2D1,CBFA2T2,ARHGAP33,RCBTB2,ASIC3,AKAP7,CRMP1,ARHGEF10,CNTNAP2,PHC2,HIPK3,PLXNC1,ENO2,STX2,EZH1,C1orf61,DPYSL4,OGA,SIGLEC8,GPD2,KCNQ3,KITLG,ADAM22,BCO1,NF1,SNTG1,POU3F4,SIDT1,PTHLH,RAB3IL1,RGS3,RGS12,KCTD17,ROM1,EMID1,RXRA,RYR1,FUZ,LIMCH1,TMCC1,EMC1,SPTAN1,SEMA4A,KIAA1107,DOCK9,PSD3,DICER1,CABIN1" Drug 5749_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ALK,MRTFA,PPP4R4,CA8,CBFA2T2,AP4M1,CRLF1,CHN2,RAB28,PLAA,TPP1,SULT4A1,ABI3BP,SLITRK5,PPP6R2,GIT2,CNIH3,STX2,FGFR1,OGA,USP19,MSL3,GPD2,GUCY1B1,HSF2,MIA2,ADAM22,ZNF862,PFKFB2,STRN3,POU3F2,TMEM104,CNTLN,ELOVL2,PTPRE,ATG16L1,KCTD17,SUGCT,MAP6D1,SLC1A7,ZNF415,SS18,MAPK8IP3,CEP68,KAZN,EXOC7,KIAA1107,GPR161,TRPC1,VIPR2,REEP1,UPF3A,MAP3K12,NT5M,NAV3,KCNAB1,TIGD6,DPF3" Drug 6810_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,PLA2G6,BIN1,OGT,ANK1,FGD2,APLP1,CDC14B,ATP2B2,CACNA1G,CFAP410,ARHGEF1,CLGN,ADGRG1,FADS2,WHRN,CRMP1,PDE4DIP,RIMS3,MAML1,CTIF,ATN1,DTNA,DTNB,EFNB3,FYN,SEPT9,GLS,GPD2,GPER1,KCNK1,KCNN2,KCNQ3,BCO1,ZNF862,PDE1C,ELOVL2,SUSD4,TRIM68,MYH14,TCP11L1,RASA3,ITSN1,PPP1R9A,FBXO11,BTBD7,LIMCH1,WDTC1,MAPK8IP3,FAM168A,ATP11A,SLC19A3,RUNDC3B,AMACR,VIPR2,SPHK2,ITM2C,NUP214" Drug 5052_UP Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ASIC1,ADD2,ADORA1,PRX,PDE8B,MARK4,CFLAR,ST3GAL5,SCAPER,CACNA1D,CALB2,HAP1,BRSK2,ARHGAP22,CLCN4,WHRN,FAM131B,RIMS3,MAML1,JAKMIP2,EDN1,EFNB3,ELAVL3,COQ7,ABCA8,DLC1,FGF12,FGFR1,DCTN2,GAD2,GNAO1,GRM3,ICA1,KIT,LMO2,GIT1,PDE3B,PFKFB2,PIK3CD,GRAMD1C,PTN,PTPRH,CCDC40,RGS10,RGS12,KCTD17,IL17RB,CNKSR2,SPTB,NCDN,PHLDB1,COBL,TBCEL,R3HDM1,CHST5,TMPRSS5,WIPF1,WNK1" Drug 2922_UP Epitiostanol [2363-58-8]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ABHD6,BIN1,CDC42BPA,PRX,PDE8B,ADGRB1,LDLRAD4,CAMK2B,HIP1R,SEPT7,TAOK2,HOMER3,CNN3,CNTN1,ABCG1,DZIP3,SPATA2,MAGI2,DMD,TRAPPC9,EDIL3,ST8SIA3,HEYL,EFNB3,MRNIP,RASGRP2,FGFR1,C1orf61,GJB1,ZNF276,GLYR1,PCSK1N,ATF7,MBP,NAP1L2,NOS1,NLE1,PLXNB1,NECAB2,MAPK8,WDR25,PTPRN2,SEC61A2,MYH14,TCP11L1,FOXRED2,SEC14L1,SLC1A3,BTBD7,ARHGAP26,RAP1GAP2,FCHO1,DAAM2,PARD3,UBE3A,CLIP2,KCNAB1,PLSCR4" Drug 2565_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADCY6,APBB2,PPP4R4,RASL11B,KIF1A,AZGP1,MPDZ,FUBP1,MAP7,NEURL1,CDO1,EPS15L1,ABI3BP,CSNK1E,CTNND2,DLG3,DRD1,EDNRA,KCNMB2,CAMKK2,GATM,ZNF276,RAPGEF4,PADI2,HTR5A,ITIH2,KCND3,KPNA5,ADAM11,MOBP,MX1,NF1,NPPA,OPRL1,SLC25A23,PMP2,MINDY2,PPP5C,PKN2,PROX1,GDPD2,PTPN13,PTPRG,PTPRN2,RGS10,TCP11L1,KCNIP1,ZNF821,ANKRD6,ZC3H13,CAMSAP2,TRIM2,PSD3,TIAM1,TMOD1,PRMT8,TRPC3,SH3GLB2" Drug 5750_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "TTYH1,NDRG2,SPARCL1,LTBP4,APBB1,BMP7,BMPR1B,CACNA1I,CAMK2B,CBS,CDH8,CDH10,CHI3L2,PLEKHB1,CNTFR,AATK,SNCAIP,SUSD5,MAML1,MFAP3L,PLPPR4,EDIL3,ELAVL3,FGFR1,DENND2A,RUNDC3A,COPS8,IL1RAPL1,ITIH2,KCND3,KCNJ5,KHK,LAMA2,NF1,NPTX2,NRCAM,NTRK2,PALM,PCDH9,PDE4D,PIK3R1,MINDY2,PPP2R2B,PTN,RET,NEK11,TRIM46,RASA3,SLC8A2,EFHD1,SNCA,KDM4B,INKA2,SYN2,CRTC1,PIK3R5,RPRM,EPM2A" Drug 2630_UP Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "APAF1,KCNAB2,PLA2G4C,ALDH4A1,GYG2,CA4,CAMK2B,ARHGEF1,SCARB1,CDH8,CHN2,LY86,LRIG1,ARHGEF10,NOS1AP,PYGO1,INTS1,DAPK3,SPOCK3,DTNA,FGFR1,GALC,SIGLEC8,ATP8A2,INPP5K,ALDH1L1,MALT1,GLYR1,GNAS,GPD1,LMO2,NPPA,NPR2,CAMKV,PURG,PACSIN1,PTHLH,C1orf54,RGS7,RGS12,FBXW7,RPH3A,SLC1A7,SLCO1A2,ZCCHC24,KDM4C,IQSEC2,VAMP1,TAL1,TBCEL,ARHGEF12,TNS1,TPM3,TRPC1,ZKSCAN5,SLC30A3,NT5M,MVB12B" Drug 4135_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ALDH7A1,CADM3,N4BP2L1,CBFA2T2,MYOM2,CDH10,JAM2,CLCN4,WHRN,SLC4A7,AATK,MICAL2,PDE4DIP,NTM,DTNB,SNX29,ELAVL2,NRN1,PTK2B,GAB1,GABRA2,SIGLEC8,NEU3,C1QL1,RND1,ATF7,ATXN2L,ICA1,KCNH2,KCNJ5,KCNMA1,KCNN1,MID1,MOBP,ADAM22,CLDN11,GPR85,PTAFR,RASGRF1,RGS10,RGS12,MYH14,RPS6KA2,SALL1,ZFP2,SH3BP2,CNKSR2,DZIP1,SLC2A5,SMARCD3,NMNAT2,EMC1,CAND2,WSCD1,TRPC1,FAM155A,WIPF1,SSPN" Drug 3364_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "KIAA1324,MRTFA,ATP1A3,ATP2B2,AZGP1,CACNA1I,CACNA2D1,CAMK2B,CCNT1,NEURL1,CACNA2D2,SLC22A6,CNN3,AKAP6,CNTNAP2,RASSF2,DAPK1,RABGAP1L,SHANK1,EFNB3,ING4,ELAVL3,ERBB2,CEND1,PTK2B,FHL1,FOXG1,SORBS1,GAD1,RUNDC3A,GNG3,GPER1,GPR37,GRIK5,HTR2A,ICA1,KITLG,ZNF862,ENPP2,EPN1,PLP1,PTAFR,RGS12,KLHL11,ST6GAL1,OGDHL,KIF21B,IZUMO4,ZC3H13,PHLDB1,AJAP1,ROBO3,TNS1,LAT2,PARP11,NUP214,ADAMTSL3,AP3B2" Drug 422_UP thioridazine hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "GAS7,APOC1,WASF1,CA12,HAP1,CAMK2G,SLC25A14,SEPT7,CHRM4,CNOT8,TAOK2,CNTN1,CRMP1,PDE4DIP,GPRASP1,SPOCK2,SRGAP3,DYNC1I1,EGR3,ETV1,EXTL2,FGFR1,PDLIM5,STAG2,ALDH1L1,GJB1,ZNF638,GNAO1,AGBL5,HSF2,IL6ST,NAP1L1,NTRK3,SETD4,SNX10,RETREG2,PKN2,RNASE1,RIC8B,PAQR6,SLC8A1,RAB3GAP1,ELMO2,CDK5RAP2,EMC1,HECW1,ZC3H13,POGZ,STX1A,PLCB1,TBL1X,OBSL1,AHCYL2,TK2,TMPRSS5,VAV1,CIAPIN1,MPPE1" Drug 4767_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ASPHD1,ARID1A,NDRG3,MRTFA,PLA2G4C,CFLAR,CA4,CACNA1D,CAMK2B,ARHGAP33,FOXN3,PLEKHB1,FADS2,WHRN,CSF1R,ARHGEF4,RIMS2,NOS1AP,MFAP3L,SLC12A6,OPTN,DENND4A,FAM198B,ST3GAL6,AFF2,ERAP1,SEPT9,RASSF8,ATXN2L,HNMT,KCNF1,KCNMA1,NNAT,NPTX1,STRN3,MAPK7,FAM120C,ZFHX4,SBF1,SLC1A7,SLC6A8,RBM34,ZC3H13,STX1A,PLCB1,ROBO3,SYNE1,DOCK9,CRTC1,DICER1,PARD3,TRIO,MICAL1,LMF1,EMSY,EVI5,EPM2A,SSPN" Drug 2991_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ABAT,NDRG2,SEMA6A,DDX3Y,ATP1A3,CDH2,DLGAP1,AKAP6,PHF14,MFAP3L,KLHL3,PARD6A,EDNRB,VPS13B,ZNF549,APC2,OLFM1,FGF12,FHL1,CAMKK2,NSG1,FYB1,GABRA1,GCK,SRCAP,SPACA9,PRDM5,RASSF8,PTGDR2,KIF5C,LIG4,PACRG,MN1,NPTX1,TREM2,PDE4A,PRKAR1B,BCAS3,CCDC40,BEND5,NEK11,KIF16B,PEX26,TNIK,ZC3H13,ATP10B,SYT1,TACR1,ROBO3,CRTC1,AP4E1,RBFOX2,LILRA4,TPM3,TRPS1,SSBP2,RPRM,XRCC4" Drug 1962_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "PLA2G6,GAS7,PDXK,SLC4A4,BID,CA12,PTBP2,CAMK2B,ARHGEF2,CDH2,FOXN3,TAOK2,KIAA1549L,CDC42BPB,SPOCK2,SPATA2,ZBTB24,C2CD2L,DLG3,DNM1,ABI1,COQ7,ETV1,POLR1B,BAIAP2,CAMKK2,OGA,STAG2,TRAF3IP2,ERAP1,GNAS,GRIK5,KIF3A,MAN1B1,KIF5C,GIT1,N6AMT1,C11orf49,RC3H2,MAPK3,MYH14,FAM192A,SH3BP2,FAM214B,SLC11A1,ELMO2,HECW1,SS18,MAPK8IP3,SYNE2,VAMP1,IQCE,TBL1X,TCF7,TRIM2,OBSL1,TRPS1,KLC2" Drug 2718_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NME5,PLA2G4C,MARK4,SLC4A4,RGS11,BMP7,CA12,CACNG1,STOML1,FHL5,CREB5,NCOR2,DAPK3,SV2B,CDON,ST8SIA3,EDN3,PLXNC1,RASGRP2,SCARA3,PRELID3A,NCKAP1,SEPT9,NEU3,ALDH1L1,GFER,GJB1,GRM1,GUCY1A2,HRH3,HTR2A,HTR5A,KCND3,KCNN1,KIF5C,KIFC3,MGAT3,MN1,ADAM22,MYH6,FXYD7,NCAM1,KCNK10,PBX1,FXYD1,LRRN3,KLK6,WDR25,SEMA6D,FRMPD1,SLC11A1,PLCB1,SYT1,SYT5,LILRA4,UBE3A,LMF1,FAM13C" Drug 4504_DN Iopromide [73334-07-3]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADORA2A,MRTFA,SEMA4G,ASPH,SLC4A4,CACNA1I,CBFA2T2,SYNGR3,MAGI1,NMT2,LY86,PICK1,CNTN1,CSF1R,SNPH,AK5,PLXNC1,TNK2,MRNIP,FGF1,HPCAL4,GAB1,GABRA2,TMEM8B,SRCAP,GNG4,FERMT2,ELOVL5,ICA1,IL6ST,IL12A,KCNJ5,KCNMA1,NF1,NNAT,OPCML,PIK3R1,MAPK8,PLPPR1,FAM120C,PID1,GSTCD,KIRREL1,TMEM206,ZNF671,SLC1A7,PPP4R3A,SLN,MAPK8IP3,MLC1,TAL1,EHBP1,AMACR,ZMYND8,RPRM,NT5M,EVI5,DPF3" Drug 2654_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ASIC1,CNTNAP1,APBB2,PPP4R4,MARK4,SLC2A11,BAIAP3,CACNA1A,NRXN2,CNTFR,AKAP7,NRG2,CSF1,ATRNL1,IPCEF1,PDE4DIP,MFAP3L,RUSC2,C2CD2L,MBNL2,HSD17B14,VPS13B,RASGRP2,SPEG,PIPOX,FAM198B,FGFR1,C1orf61,SEMA4D,FLNC,NSG1,SIGLEC8,RND1,GNAO1,GSTM5,RASSF8,ATXN2L,INPP5B,KCND3,LSS,ZNF862,NPPA,NLE1,PPP5C,SNRK,SHANK2,SLN,ZC3H13,SPTAN1,IQSEC2,ARC,ROBO3,THRA,HEY1,TK2,SPHK2,GDPD5,TIGD6" Drug 6666_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "RALGAPA1,ASPHD1,ACTN2,AGT,SEMA6A,MRTFA,BMPR1B,KALRN,DNAJB5,IFFO1,CPS1,PDE4DIP,MAGI2,SRGAP3,DMPK,ING4,MRNIP,LRRC17,DLC1,FGF1,OLFM1,SORBS1,OGA,MYOZ2,GNAO1,IRF8,KCNMA1,KCNN1,KHK,MIA2,AFDN,MMP16,MSR1,MYH3,GON4L,RASGRF1,SELL,RASA3,NTNG1,SLITRK3,ANKRD6,SLC11A1,SLC12A4,ZNF334,CXXC4,ZNF423,ATP10B,PHLDB1,SYT11,COBL,SYT5,FAM189A1,ZFPM2,TK2,FLRT2,LAT2,ZNF225,KCNAB1" Drug 3988_UP Cinchonine [118-10-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADD2,AP2A2,AQP4,PPP4R4,CDK13,NRP2,CAPN3,KRIT1,NEURL1,CHGB,LY86,AKAP5,IFFO1,DCAF4,SPOCK2,RABGAP1L,DTNB,EDNRA,EPHA5,NRN1,GAB1,GAD2,HBS1L,GPM6B,GPR17,STON1,MAN2A2,MATN3,MIA2,MYL3,NTRK3,SPATA6,LRRN3,PSD,PTPRB,PTPRN2,RFX2,RPS20,SEMA6D,DOCK10,OGDHL,SNCA,KIF13A,TNIK,ACSBG1,MLC1,ATP11A,TACR1,EXOC7,DAAM2,TRIO,ZMYND8,VIPR2,SF1,ZNF24,WNK1,MAP3K12,PARP6" Drug 4407_DN Terconazole [67915-31-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "AMPD3,BIN1,AMT,APBB2,SLC4A4,CDC42,RCBTB2,SOCS6,TAOK2,CNTN1,WHRN,SPOCK2,RABGAP1L,CNNM1,EGFR,KIAA1109,KHDRBS3,GPR153,GAB1,GAD1,ALDH1L1,RUNDC3A,TJAP1,IPO5,LMO2,MAN2A2,MAP4,TM6SF1,ADAM22,NEUROD1,STRN3,MAPK7,RAB3A,RAB3IL1,CEP97,RAD52,C1orf54,RGS12,EMID1,FAM214B,KDM4B,TSNAXIP1,IQSEC2,THSD1,TTBK2,ROBO3,IQCE,TCF7L2,PCDHA6,AHCYL2,DICER1,CABIN1,HIRA,VGF,SPHK2,SYNC,EMSY,SLC17A7" Drug 6380_UP STOCK1N-35215; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ACTN2,ADRA1D,MRTFA,AMPH,SEMA7A,APP,ALDH7A1,ADAM23,ADGRB2,CALB2,CBS,MAGI1,RAB33A,IFFO1,EDRF1,LYPD1,TRAPPC9,ATN1,EFNB3,FGR,CAMSAP1,AGAP2,DCTN2,NSG1,OGA,GAB1,DISC1,ALDH1L1,SRCAP,GNG3,ATXN2L,ICA1,IL6R,INPP5B,KCND3,KCNF1,KCNJ5,MAP2,MAPT,NTRK2,PCDH9,MBOAT7,PTN,TTLL7,FBXW7,TCP11L1,DOCK10,BCAN,SLC6A11,SLC9A5,SNAP25,HECW1,KIAA1107,SLC44A1,TNS1,TPM1,TPM3,NAV3" Drug 6010_UP Triamterene [396-01-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "DPF1,C1QTNF3,APAF1,CADM3,BAIAP3,CAMK2B,HIP1R,ATN1,SIDT2,ING4,ELAVL4,IGSF6,ZNF391,REEP2,FGF1,KHDRBS3,ALDH1L1,SRCAP,PCDH17,RUNDC3A,GRK4,KCNJ3,MAPT,AFDN,MMP17,ADAM22,MYCN,NNAT,PIK3CD,RETREG1,PLCD1,TNPO2,POU6F1,PTAFR,TTLL7,MYH14,CARF,GSTCD,WLS,SBF1,ASIC4,ZNF821,SLC2A5,SMTN,KDM4C,PEG10,CDK19,ZBTB43,INKA2,PLCB1,SMG6,WSCD1,DOCK9,PCDHA6,TEX15,VGF,CLDND1,HPS4" Drug 1491_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "SYN3,NDRG2,ADD2,PLA2G6,BCAR3,APOC1,CFLAR,CDK5R1,SCAPER,GYG2,ARHGAP33,CLGN,CLCN3,QKI,PPP6R2,DMPK,ST8SIA3,DLC1,KAT8,FHL1,DISC1,GLYR1,GPER1,GPR37,GRB10,RASSF8,MBD1,MDM4,MEF2C,KITLG,MMP16,ADAM22,NF1,SLCO1C1,NOS1,RETREG1,PPARA,PTHLH,RAD52,FAM184A,RGS12,STUM,TRA2B,ZNF365,PPP4R3A,ZCCHC24,SPART,VAMP1,SYN2,IQCE,CHST8,TK2,BEX4,KAT6B,TPD52,KCNAB1,ADAMTSL3,RNF170" Drug 6964_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NME5,LTBP4,MRTFA,BIN1,FAM131A,APOC1,SEMA4G,MARCH3,MARK4,CACNA1I,CHRNB2,QKI,COL4A5,MYRIP,FEZ1,GPRASP1,ARHGAP32,JAKMIP2,OPTN,EFNA3,EZH1,F3,ACSL4,DLC1,FECH,C1orf61,CACFD1,IL6R,ITGA7,MAN2A2,MAP4,MBD1,MYL3,ZNF862,PENK,PTPRE,RGS12,ZFHX4,FBXW7,SLC1A7,PEX26,PKNOX2,SHANK2,MYH15,TSNAXIP1,IQSEC2,ELOVL4,STX1A,ADGRL3,WSCD1,KIAA0930,TNS2,DNAH7,TK2,TMOD1,TPM1,ZMYND8,KCNAB1" Drug 6131_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "EPB41L5,ASPH,SLC4A4,NRP2,SYNJ2,CFAP410,CACNA2D1,CDH2,CHRNB2,TAOK2,SLIT2,DNAJB5,CREM,DCAF4,SPOCK2,PARD6A,EFNA3,MTSS1L,STX2,ERBB2,EFS,ETV1,F5,FGF1,FOXG1,CAP2,ZMYND11,POLL,STON1,GRIK1,GRM1,KLF12,HLF,ICA1,KCND3,KCNJ5,CD200,NTRK2,PDE4D,PFKFB4,MINDY2,FAM120C,MYH14,CARF,KCNIP1,SELL,PKNOX2,SLCO1A2,PALLD,TMCC1,SPTAN1,TBCEL,TCF4,TRIM2,TF,KCNE5,MKRN3,SPHK2" Drug 6152_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "BRAP,C1QTNF1,SYT13,CDC42BPA,APOC1,CDC14B,PLA2G4C,BMP7,SYNJ2,MTMR3,GYG2,CHRNB2,TCEAL2,CNIH3,SMG7,EXOG,RCAN1,DTNA,FAM13A,ING4,EIF1,EPB41,DMTN,STX2,FER,AGAP2,EFCAB2,SORBS1,PDLIM5,KHDRBS3,GCNT2,GLYR1,GPD1,PCLO,KIF3A,MMP16,MYO6,NTRK2,OCRL,CLDN11,GDPD2,RGS4,CARF,RPS20,SYNDIG1,FERMT1,FUZ,NTNG1,TMCC1,KDM4B,ARHGAP26,SPTAN1,DDN,DMXL2,CRB1,TLR4,HIRA,ACTR3B" Drug 2191_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "CDC42BPA,APBB2,APOC1,CDK10,SEMA4G,PDE8B,DNAH17,PTCH2,ADGRB1,NEURL1,MAGI1,CACNA2D2,CHM,CHRNB2,JAM2,TAOK2,ZFYVE9,COL4A5,SIPA1L1,EDRF1,DBT,DLG3,ELAVL2,TNK2,FER,IQCG,GPR153,DLL3,ZMYND11,GLRB,GRM1,KCNJ4,KCNQ3,KHK,FXYD6,NNAT,PLEC,EPB41L4B,BEND5,RYR1,RYR3,SEMA6D,SLC1A3,SMTN,EMC1,PEG10,SPTB,NPAS3,LHPP,ZFR2,ATP11A,CAMSAP2,TBCEL,TCF4,RPGRIP1L,TNS2,SLC35G2,SPHK2" Drug 6400_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "APAF1,APBA2,APC,GAS7,APP,PPP4R4,ALDH4A1,ADGRB2,BTK,BAIAP3,CAMK2B,ARHGEF2,TAOK2,STOML1,SLITRK5,FRMPD4,MFAP3L,DTNA,EFCAB2,DISC1,TDRKH,GPER1,GRK4,CNTRL,CACFD1,GRM1,SHISAL1,IGF1,ITGA7,ITIH2,ADAM22,PDGFRA,PFKFB2,PIK3CD,CEP41,PRKAR1B,PTCH1,MARCH1,BEND5,RGS3,KCTD17,RNASE1,CARF,RPS20,KCNIP1,SH3BP2,ASAP3,DZIP1,SPP1,DDN,TAL1,TBCEL,TCF4,CDK20,TRO,CA14,RPRM,SPHK2" Drug 6829_UP Althiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "PLA2G6,MRTFA,AMPD3,AMT,APAF1,SEMA4G,PPP4R4,ATP2B3,CA4,CACNA1A,ADGRG1,SLIT2,COL9A3,RCHY1,NECTIN3,CSF1R,PLCH2,CHD5,VCAN,MFAP3L,RUSC2,CDON,SHANK1,DOCK2,EFNB3,MBNL2,ERGIC3,GAP43,ALDH1L1,POLL,GNAL,GPR37,GRIN1,IL6R,SMAD1,ADAM22,NNAT,OMG,CLDN11,PDZRN4,PTHLH,FAM120C,RAB3IL1,RAD52,RGS4,MYH14,KLHDC8A,TCP11L1,RASA3,FBXO11,TAL1,SZT2,PCDHGA10,DICER1,FAM155A,SLC17A7,KCNAB1,NUP214" Drug 4189_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ASPHD1,ADCY6,PLA2G6,APOC1,APP,PDE8B,KIF1A,ARHGEF7,CFAP410,SOCS6,CLCN3,NCOR2,CSF1,VCAN,KIAA0513,CTIF,MFAP3L,EXOG,DTNA,EFNA3,MRNIP,EPHA5,F5,FGFR1,ANKFY1,TMEM8B,GRIK2,GRM8,KCNF1,LIFR,PACRG,PDE4D,RETREG1,ST8SIA5,PPARA,GRAMD1C,BCAS3,PTPRN2,FBXW7,MRAS,SCG5,FRMPD1,ST6GAL1,SLC1A7,ARHGEF40,SLN,EMC1,SPTAN1,CAMTA2,VAMP1,TRIM2,CRTC1,GPR161,VGF,REEP1,ZNF225,KCNAB1,UBE3B" Drug 4654_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "SYN3,ACTN2,PLA2G6,TRMT9B,AMPD3,ASPA,CADM3,RGS11,NRP2,CAMK2B,NEURL1,DLGAP2,CHGB,LY86,AKAP5,IFFO1,ABCG1,RIMS2,CTIF,MAGI2,ARNT2,HS3ST2,CELSR3,HSD17B14,RASGRP2,NCALD,APC2,FGFR1,FYN,ERAP1,SIGLEC8,PCDH17,GRK4,CACFD1,AP4S1,SOX21,SMAD1,AFDN,NOVA2,PCDHGC3,PDGFRA,MINDY2,PTPRN2,SCN2B,ASIC4,SELL,SLCO1A2,SOX2,NPAS3,SYN2,PCDHGA10,THBS4,CDK20,BEST1,ZIC3,PRDM2,KCNAB1,MVB12B" Drug 5605_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ARID1A,NDRG2,ADD3,AMT,APBA2,GAS7,CFLAR,MTMR3,CACNB2,CBFA2T2,CLGN,RCBTB2,STOML1,SH2B1,NCOR1,DOCK4,SMG7,MED12,OPTN,EFNA3,MBNL2,STX2,FGFR1,OGA,GLYR1,RAB30,GNG3,TDRKH,GPR19,NR3C1,HNMT,INPP1,KCNF1,MSI1,NPTX1,MED1,APTX,PLPPR1,SBF1,SEC14L1,FERMT1,WDTC1,ZCCHC24,SPART,PLCB1,ASTN2,SEMA4A,TBCEL,DMXL2,TRIM2,CLASP1,PSD3,CRTC1,KCTD2,PARD3,RUNDC3B,SLC17A7,SSPN" Drug 4222_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "FUBP1,DLGAP1,GPR37L1,CBARP,CHN2,CHRNA4,NRXN3,NRXN2,TPP1,RAB26,CSF1,ATN1,DTNA,EDN3,LRRC23,ERBB4,EFS,KIAA1109,CAMSAP1,AFF2,EFCAB2,ARPP21,SIGLEC8,SRCAP,GFER,CSDC2,STMN2,ADAMTS8,PTGDR2,HTR5A,KCNC1,ADAM22,PCSK5,PTPRN2,RASGRF1,RGR,TCP11L1,ASAP3,SLC4A3,PREX2,PKNOX2,SLC15A2,CXXC4,IZUMO4,MAPK8IP3,SYP,KAZN,ADGRL3,PHF24,SPX,THRA,TIE1,SEZ6L,TRIO,TRO,WIPF1,KCNK12,DNALI1" Drug 3702_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "C1QTNF3,APC,CDK10,BTRC,FAM189A2,CNTFR,IQCK,BAG4,CRY2,NCOR2,CSNK1E,CDON,EDNRA,SGK2,SIDT2,NCALD,CDKL3,SCML2,FGF1,TRMO,OGA,FYN,TRAF3IP2,GLS,BTN2A1,HSD17B1,SHISAL1,INPP5B,KHK,KIFC3,MAPT,GIT1,NF1,OPRL1,PRKAR1B,CNTLN,PTPRH,RAD51D,ZNF821,ST6GAL1,BCAN,ELMO2,SNCA,SP4,TROVE2,THSD1,SS18,MAPK8IP3,SYT11,IQCE,TCF4,DNAH7,CDK20,VGF,LMF1,NSD2,KLC2,SEMA3B" Drug 3555_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADORA1,KIAA1324,APBA2,BCAS1,ATP1A3,ALDH7A1,CFAP410,RCBTB2,SLIT2,MYRIP,CSF1R,DCAF4,RIPOR2,RASSF2,DCC,SPOCK3,TMCC2,DLG4,DNAH9,ATN1,EFNA3,ERCC2,DLC1,CAMSAP1,FYB1,FYN,DISC1,GATM,ALDH1L1,GDF9,GPR162,CYP46A1,RND1,ADAMTS8,GRM2,ATXN2L,ITPKA,KCNB1,PACRG,SMAD1,MX1,PALM,PDE1A,RASGRF1,RGS4,RGS12,RPS6KA2,MRAS,SH3BP2,SLN,COA1,WDTC1,TNS2,GPR161,TRO,WIPF1,MVB12B,PLSCR4" Drug 5016_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "DPF1,ALCAM,MRTFA,CDC14B,MARK4,SLC16A4,CDH8,CRLF1,CACNA2D2,SOCS6,CLCN4,CNTNAP2,RIMS3,DBT,DCT,PARD6A,EXOG,DMPK,EDN1,SIDT2,CDKL3,FGFR1,FOXG1,OGA,ATP8A2,SRCAP,GPR22,IRAK3,IL6ST,ITIH2,KCNH2,KIF5A,KIF5C,KITLG,ADAM22,PENK,PIK3CD,MED1,PRKAR1B,MAPK10,RAD51D,RALGDS,ZFHX4,SLC20A2,SLCO1A2,SMARCD3,LIMCH1,DOK5,ZC3H13,CDK19,RBM26,SZT2,PSD3,PARD3,HIRA,UCHL1,ZFP37,SEMA3B" Drug 2254_DN Etodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,BEGAIN,APOC1,ARRB2,DNAH17,RASL11B,ALDH4A1,CADM3,CCNT1,ARHGEF2,CACNA2D2,PLEKHB1,SLIT2,LHX2,CLTB,BAG4,SIPA1L1,GREB1,RIMS2,PPP6R2,OPTN,RBM12,PLXNC1,MRNIP,SEMA4D,TPK1,SEPT9,GCNT2,GLYR1,GNG4,STON1,CNTRL,GRIK5,CACFD1,GSN,ELOVL5,MBD1,MSI1,NOS1,NUMA1,NLE1,STRN3,MAPK8,GRAMD1C,PRODH,ELOVL2,RAB3A,SNCA,WDTC1,TSNAXIP1,KIAA0930,TNS2,CABIN1,SLC30A3,EMSY,SEMA3B,NUP214,TIGD6" Drug 2759_UP Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,APBA2,MARK4,SCAPER,GYG2,CFAP410,CDC42,GPR37L1,SLIT2,CRMP1,TENM4,DCAF4,SEC14L5,TMCC2,KBTBD11,EFNA3,ELAVL3,ETV1,ANKMY1,FGFR1,FHL1,FOXG1,GAB1,TRAF3IP2,TMEM8B,RUNDC3A,GNG3,LILRA2,GRB10,GRIK1,ADAMTS13,GRM7,KCNMA1,MAOB,CD200,MX1,PLEC,PPP5C,MAPK10,PTHLH,ZNF493,KCTD17,ZFHX4,RASA3,LIMCH1,WDTC1,TROVE2,CAMTA2,ARC,ATP11A,DOCK9,CRTC1,PCDHA5,CHST8,UBE3A,VIPR2,MICAL1,DNALI1" Drug 2536_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ASIC1,NDRG2,GRAMD1B,TRMT9B,AMT,CDC42BPA,KCNAB2,LDLRAD4,CAMK2G,ZFYVE9,AKAP7,IQCK,DAPK3,CTIF,DBT,RUSC2,RCAN1,DTNA,EEF1A2,MTSS1L,F8,ANKFY1,SEPT9,GART,COPS8,MSL3,GNG3,GPM6B,GRM8,NCKAP1L,ZNF862,NNAT,OLR1,PDE4D,RETREG1,MINDY2,MAPK3,PTK2,ZSCAN32,FAM120C,FRMPD1,DOCK10,EPN2,SRPK2,STX1A,ADGRL3,ZEB1,TK2,TNS1,ZKSCAN5,FLRT2,LAT2,XRCC4,ZNF45,REEP1,PRDM2,FAM13C,TIGD6" Drug 3744_UP Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "DPF1,ACTN2,PLA2G6,ANK2,ZSCAN18,ADAM23,MPDZ,NRP2,FUBP1,SCAPER,C5,IL33,RUNX1T1,PLCH2,RIMS2,CTIF,ARNT2,DTNB,RGS17,MTSS1L,IQCG,GNAO1,GPR19,LPAR4,GPER1,GRM2,GRM8,HTR2A,ICA1,C2orf72,TJAP1,KCNB1,KCND3,KCNJ4,LAMA2,MDFI,AFDN,MYH6,MYT1,NEUROD1,NOVA2,NPTX1,PDE4A,LRRN3,CNNM2,CARF,KCNIP1,SH3BP2,BCAN,FAIM2,ARC,ASTN2,MCF2L,TBCEL,ZEB1,TNS1,FLRT2,SLC13A3" Drug 4653_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "TTYH1,ABAT,NR0B1,SYT13,APC,AQP4,PPP4R4,N4BP2L1,IL33,KALRN,USP2,CDH10,DLGAP1,CHI3L2,SLC22A6,NRXN2,COL9A3,RGS6,AK5,ARNT2,TOM1,SRPK3,ERBB4,NRN1,C1orf61,POLL,GNAL,GPD1,GPM6A,GRIN1,HPCA,KCND3,KCNF1,KCNJ5,VWA5A,MAP2,ADAM11,AFDN,MOBP,PALM,PPP2R2B,CNNM2,KLHDC8A,TCP11L1,SELL,MRAS,SLA,SNAP25,SOX10,SPP1,SPTB,ARC,RALYL,TLR4,CHST5,TRO,UBE3A,KCNAB1" Drug 4102_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ABR,AMH,APC,DNAH17,ASTN1,ALDH4A1,ATM,NOL4,BACH1,CFLAR,CACNA1A,PLEKHB1,DNAJB5,CNTFR,WHRN,AKAP5,ENTPD4,NCOR2,CSF1,RIMS2,MFAP3L,ECM2,CNNM1,ING4,COQ7,ZNF549,ETV1,FGF1,FGFR1,FLT1,TDRKH,TJAP1,IL12A,MOBP,NNAT,NOVA2,NUMA1,PAK3,EPN1,SPATA6,FAM184A,ZMAT4,CCDC102B,RPS20,SELL,SNCA,KDM4B,TSNAXIP1,ASTN2,MCF2L,PCDHGA10,CRTC1,TK2,LILRA4,TRIO,LAT2,WNK1,SEMA3B" Drug 6732_DN N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "AK2,BIN1,ARHGDIG,ATP1A3,KIF1A,SYNJ1,CACNA1I,LDLRAD4,B4GALT6,DNAJB5,WHRN,CRMP1,NCOR2,CNTNAP2,RIMS3,BRINP1,ST8SIA3,SIDT2,EIF4G2,KIAA1109,BAIAP2,LYVE1,GRK4,GRM1,ICA1,SCIN,IL11RA,KCNN1,KIF5C,MN1,MYT1,NF1,PLCD1,PLXNB1,PRPH,BCAS3,CNTLN,RAB3A,RGS10,KIRREL1,SH3BP2,LIMS2,FAM214B,SMARCD3,RBM34,BEX1,SPTAN1,DDN,PHLDB1,EXOC7,TCF4,THRA,TNS1,METTL3,MICAL1,NT5M,PCBP4,NUP214" Drug 3365_UP Ioversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,ADORA1,ADORA2A,AP2A2,C1QTNF1,TRMT9B,APAF1,APBA2,KCNAB2,APC,MTMR3,CDK5R2,LDLRAD4,CFAP410,HIP1R,CBFA2T2,CDO1,VCAN,RASSF2,INTS1,HIPK3,EGFR,ELAVL3,TNK2,F5,PTK2B,GCNT2,GPR22,GPER1,NR3C1,GRM1,IL1RAPL1,GUCY1B1,VSIG4,INPP1,KIF5A,MEF2C,ZNF862,NELL2,NNAT,NOVA2,PIK3CD,PPP5C,PTCH1,RAD52,ZMAT4,BCAN,SHANK2,DOK5,LMO3,SYN2,ADGRL3,TRPM2,LAT2,SLC30A3,KCNAB1,CAMK1G,SENP7" Drug 4069_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "BBOX1,BEGAIN,GAS7,APP,CDC14B,ARHGDIG,MYOM1,ADGRB2,BAIAP3,CALB2,SLC16A4,ENTPD2,NRXN3,NRXN2,SLC4A8,CSF1R,ST18,SEC14L5,RIMS3,SPOCK2,SPOCK3,NTM,EDN3,EFNB3,RASGRP2,CSPG5,OGA,GAP43,GNAO1,LILRB4,GRM8,GUCY1A2,PTGDR2,KLF12,HLF,IRF8,LAMA2,MMP16,MOBP,ADAM22,NF1,ENPP2,PHKG1,PRRX1,PTAFR,ACSS3,RGS4,SCN2B,HKDC1,ELMO2,HECW1,ATP10B,SYT11,SYT5,TAL1,DAAM2,NUP214,SENP7" Drug 2848_DN Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "APC,STX16,CFLAR,CA4,CLGN,HOMER3,COL4A5,CREM,SOCS5,PDE4DIP,HP1BP3,SMG7,TRAPPC9,RCAN1,DTNA,EDNRA,FCF1,CNNM1,LRRC23,FAM198B,FHL1,TPK1,ERAP1,SRCAP,CRCP,RAB30,NR3C1,IL6ST,MAP4,MDM4,MMP16,ADAM22,LYRM9,NPR2,NPTX1,PDE3B,FAM184A,RGS10,TCP11L1,WLS,SBF1,FAM214B,EMC1,CDK19,ST5,PLCB1,ARC,KAZN,ZNF34,SLC44A1,TK2,VGF,VIPR2,REEP1,SYNC,EMSY,PCBP4,PHTF2" Drug 2516_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "C1QTNF1,BCAR3,BIN1,CDC14B,PRX,ATP1A3,AZGP1,FGF17,CFAP410,CACNG1,ARHGAP33,NRXN1,HAPLN1,TOX,ZNF337,SPOCK2,ATN1,DYRK1A,SNX29,CELSR3,ING4,ELAVL3,TUBB4A,DLC1,KIAA1109,FGFR1,FGFR3,FHL1,ERAP1,SIGLEC8,GRIA1,HAS2,KLF12,ICA1,IL6ST,SAMD14,FXYD6,NCAM1,NEFM,POU3F2,PRKAR1B,PTAFR,RFX2,RGS4,RGS12,RPE65,SEC14L1,SLCO1A2,DOK5,SPART,MAPK8IP3,TACR1,DNMBP,ARHGEF12,SLC35G2,TRO,SLC17A7,CAMK1G" Drug 3115_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ACTN2,KIDINS220,SPARCL1,AMPH,LGR5,SLC2A11,ADAM23,FUBP1,CA12,HIP1R,SCARB1,SEPT7,CHM,EPS15L1,PLAA,CREB5,PDE4DIP,RIMS2,DAPK3,DLG2,CDON,DRD1,E2F5,SIDT2,RASGRP2,ETV1,FOXG1,KHDRBS3,SIGLEC8,ATP8A2,SRCAP,ADAM28,POLL,GPD2,GPR22,GUCY1A1,HRH3,SCRG1,AFDN,MPP2,NTRK2,NUMA1,PIK3CD,PMS2,MAPK8,VPS13C,PTPRN,RASGRF1,ASAP3,ABLIM3,SLCO1A2,PALLD,HECW1,SS18,SEPT8,MCF2L,TMOD1,SLC17A7" Drug 3007_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "PLA2G6,AQP4,SEMA4G,SLC4A4,BMP7,CACNA1G,BTRC,CA12,HIP1R,STOML1,PICK1,SLC4A8,SEC14L5,MFAP3L,KLHL3,EXOG,DMD,ATN1,EXTL1,FHL1,CSPG5,GALC,GATM,GLS,SPACA9,GRIN1,ATXN2L,HPCA,SCIN,IL6ST,KCNJ3,KCNN1,KHK,LMO1,MMP16,SCG3,NOS1,OXTR,PCSK5,CCSER2,PPP5C,BCAS3,GDPD2,TTLL7,SEC61A2,CXXC4,SMARCD3,EXOC7,DNMBP,TAL1,CRTC1,HIF3A,SSBP2,UBE3A,FLRT2,VSNL1,SPHK2,PRDM2" Drug 3388_UP Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,ADCY2,ADORA1,ADRA1D,KIDINS220,PLA2G6,MARK4,N4BP2L1,CACNA1I,CACNA2D1,CAMK2B,CAST,BRSK2,CACNA2D2,SLIT2,TPP1,WHRN,SLITRK5,TOX,INTS1,DGKG,DAPK3,EGR3,ERCC2,GABRG2,GATM,GPER1,GRB10,GRIK5,GRM2,NXPH3,TJAP1,IL11RA,ITGAM,JAK2,KCNMA1,MAN2A2,MAP4,MGAT3,NF1,NPR2,TREM2,MAPK7,MAPK8,ZDHHC14,RET,RGS12,TMEM206,SYBU,SOX2,ATP10B,FCHO1,MAPK8IP3,ARC,CRTC1,TIAM1,SEMA3B,EPM2A" Drug 3867_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "ADCY2,LTBP4,ALK,ANK1,APBA2,KCNAB2,APOC1,ADGRB1,SGCE,CFAP410,CDH2,CHRNB2,CNTN1,AKAP5,CRY2,CSNK1E,PPP6R2,SEC14L5,CNIH3,RUSC2,ATN1,ING4,ELAVL3,SPEG,CEND1,REEP2,TUBB4A,OLFM1,CAMSAP1,C1orf61,EFCAB2,GLS,GRM7,KCNJ5,KIFC3,MAN2A2,MGAT3,AFDN,MMP17,MOBP,MX1,OPRL1,TMOD2,PIK3CD,NECAB2,PRKCB,RAB3A,RGS10,SLC11A1,PEG10,SPTB,RBM26,LMO3,ARC,POPDC3,ZEB1,TMOD1,XRCC4" Drug 255_DN dexamethasone; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "NDRG2,C1QTNF1,ANK1,APAF1,APP,NRP2,SYNJ2,BAIAP3,ENTPD6,ARHGAP33,CLCN3,CNR1,C2CD2,HINFP,NCOR2,AATK,RIMS2,EXOG,DSCAM,OPTN,EFNB3,FAM13A,MBNL2,RGS17,LRRC23,STX2,VPS26C,SMC2,CAMKK2,GAD2,MALT1,LILRA2,RNFT2,ADAMTS6,ITPKB,AFF1,FXYD1,PLXNB1,MAPK8,PYGM,FOXRED2,STUM,SUPT20H,AMBRA1,CDK5RAP2,KDM4B,SPTAN1,SPART,CLSTN2,PHLDB1,KAZN,EXOC7,SEZ6L,TSC2,ZNF184,GDPD5,MPPE1,NUP214" Drug 7149_UP Aconitine [302-27-2]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.14E-07 3.99E-02 2.16E-05 2.46E-04 58 197 "SHROOM2,BTRC,SOCS6,ZFYVE9,HOMER3,ARMC8,ARHGEF10,PDE4DIP,EDRF1,HDAC9,ARMCX2,LYPD1,SMG7,EXOG,MAMLD1,MBNL2,AASS,ETV1,ANKMY1,KIAA1109,FGF1,FGF13,BAIAP2,TRMO,OGA,GAD1,SEPT9,RASSF8,MAPT,MATN3,MMP16,NF1,PLCD1,STRN3,PPARA,PTPA,MAPK8,PRPH,SAMD9,ZSCAN32,PTPRE,PEX5,GTDC1,MRPS18A,SCG5,ST6GAL1,FAM214B,KDM4D,SHANK2,NXT2,ELOVL4,VPS13A,DNAH7,TRIO,TRPC1,EIF4ENIF1,EMSY,RNF170" Drug 1150_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.29E-07 4.06E-02 2.20E-05 2.50E-04 56 188 "ABHD6,MTUS1,APBB2,APP,PPP4R4,ARNTL,NCOA1,ST3GAL5,CAST,INA,CDO1,CHN2,DNAJB5,FEZ1,PDE4DIP,SLITRK5,PPP1R16B,DOCK4,ZFYVE16,RIMS3,KIAA0753,DTNA,FAM13A,ABI2,CDKL3,EXTL2,PCYOX1,GABRA4,PADI2,ITGA7,VWA5A,MAP4,MITF,SIDT1,PTCH1,RAP1GAP,RPS6KA2,WLS,SATB1,ITSN1,ANKRD6,FAM214B,TMCC1,KIF1B,RGL1,STXBP1,PJA1,DNMBP,TCF4,ZEB1,TNNT1,RBFOX2,TPM1,NPDC1,GDPD5,FZD3" Drug ctd:D003976 Diazinon CTD 8.58E-07 4.20E-02 2.28E-05 2.59E-04 308 1525 "CPNE2,ASIC2,ACHE,ACLY,ABHD6,ACTN1,ARID1A,NDRG2,ADCY2,ADCY8,HHATL,CDC7,FZD9,UNC5A,ADRB2,AP2A2,TBC1D14,PLA2G6,MRTFA,ZNF687,BIN1,SEMA7A,APAF1,APBB1,PPFIA3,AQP6,MADD,SPTBN4,ARHGAP5,ARRB1,CDK13,BRINP2,CHRD,ATM,ATP1A1,ATP2B3,AZGP1,BCHE,BCL7A,FGF17,CFLAR,AP1M1,CACNA1G,BAIAP3,DDR1,CALM1,CAMK2D,CAMK2G,CANX,HIP1R,CCNH,AIFM1,CD86,SCARB1,AP4M1,CDH8,LGI1,CCPG1,COPB2,CHGA,CHGB,CHRM1,CHRM4,CHRNA4,CHRNB2,NRXN2,LY86,ARHGEF6,PICK1,ABCG1,PHACTR3,GPSM1,CX3CR1,DOCK4,KCTD8,DAPK3,BRINP1,DBN1,ELMSAN1,MYEF2,C2CD2L,SMG7,PARD6A,TMCC2,SLC29A4,DNM2,SHANK1,CPEB2,CASP8AP2,FIS1,EDN3,HEYL,EFNA2,SH3GLB1,EGFR,RGS17,PAN3,DMTN,SRRM1,RASL12,F3,AMZ2,PTK2B,TUBB4A,RACK1,FECH,FGF1,FGF12,FGF14,FGFR1,FGFR3,PRKAG2,MEX3B,FOXM1,FOXO3,WDR83,ZCCHC17,CINP,USP16,APOPT1,ERGIC3,CGREF1,FYN,DKK3,IQGAP2,GAP43,CPLX2,GCNT2,ARFIP1,GFAP,NTNG2,GLYR1,AIFM3,GNAO1,FERMT2,GPT2,GPR17,GRIA1,GRIA2,DIDO1,GRIA4,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM7,GRM8,GSTM5,GSTT2,ZHX1,NXPH3,PACSIN2,MAN1B1,HTR2A,HTR5A,FAAP20,IDH3B,IGF1,KNDC1,IL12A,INPP5B,ITPKA,KCNA1,KCNA2,KCNK1,GATD1,KIT,CAMK2N2,SFXN5,VWA5A,LSS,MAOB,TM6SF1,MDM4,MN1,MPP2,GIT1,JAKMIP3,ADAM22,SAMD14,MYCN,MYO9A,NBL1,RCOR2,NEFM,NEFH,NFYA,NKX2-2,NNAT,NPY,NPR2,NTRK2,NTRK3,PAX6,PCMT1,PCSK5,PDCD2,PDE1A,PDE1C,PDE3A,PFKP,ABCB1,PKD1,TMEM38A,KCTD15,PMP22,PILRA,POLG,SH3KBP1,POLR2F,PPARA,PPP5C,PRKAB2,PRKCZ,MAPK3,CNNM2,PSD,QRICH1,PTCH1,PTN,RAB3IL1,PID1,RAP1GAP,DPF2,RET,REV3L,RFX3,RGS3,RGS10,ARHGEF10L,MRAP2,EPHA10,SYNDIG1,HSD11B1L,S100B,MAPK12,SCN2A,HES6,SMPD3,CNKSR2,SLC1A2,SLC1A3,SLC6A8,SLC6A9,SIRT2,SLC12A4,SMARCE1,SNCB,RBM34,KDM4B,SON,WDTC1,KDM3A,SP4,PEG10,CAMTA2,CEP68,STX1A,GSE1,JMJD6,PLCB1,TAC1,TAF6,MCF2L,VWC2,CUX2,TCF7,WDR7,ZMAT3,AKTIP,THRA,NACC2,ICAM5,TLR4,FAM124A,TP53BP2,LILRA4,CDK20,NR2C2,TUB,UCHL1,BCL2L13,MGAT5B,MTCH1,PLPPR2,VLDLR,CLIP2,KLC2,CFAP298,ZNF540,TFIP11,SYNC,EMSY,SLC38A1,PRDM10,SEMA3B,SIGLEC10,PCBP4,PLD4,FZD3,RTN4,AP3B2" Drug CID000003386 fluoxetine Stitch 8.64E-07 4.23E-02 2.29E-05 2.61E-04 64 225 "SERPINA3,ADAR,ADRA1D,ADRA1B,ADRB2,ATM,ATP2A2,CACNA1I,CACNA1G,CCK,CHRM1,CHRNA4,CHRNB2,NRG2,DBN1,DRD1,STX2,EFS,ZMYND10,PPP1R1B,AFF2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,LOXL3,GRIA1,NR3C1,HNRNPK,HTR2A,HTR5A,KCNA4,KCNC1,KCNH2,KCNK2,KCNN2,MAOB,MBD1,TAGLN3,NPY,NOVA2,GPR88,CDK18,PDE4B,PDE4D,PDYN,PRODH,CARF,GLDN,S100B,BEX1,SYP,TACR1,TRH,VGF,TUBA1A,SLC17A7,SLC17A6,FXR1" Drug CID000005115 4CPG Stitch 8.74E-07 4.29E-02 2.32E-05 2.64E-04 19 38 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,SLC1A2,SLC1A3,VSNL1" Drug 2829_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "ARID1A,BIN1,CDC42BPA,APBB2,PPFIA3,ATM,SLC4A4,CFLAR,BAIAP3,SLC16A4,ARHGEF2,RCBTB2,ZFYVE9,STOML1,CSF1R,GREB1,NOS1AP,MAML1,ARMCX2,DRD1,DYRK1A,SEZ6L2,SGK2,EFNB3,ANKMY1,FGF13,FGFR1,SORBS1,MYOZ2,HPGDS,GRM7,ITPKA,ITPKB,IPO5,MIA2,ADAM22,NNAT,PCSK2,MBOAT7,PACSIN1,LRRN3,RELN,SNRK,CCDC40,ROM1,RORB,ASAP3,PREX2,PEX26,SOX3,ZCCHC24,CDK19,TROVE2,SYT11,WSCD1,SLC30A3,WNK1" Drug CID000104822 dihydropyridine Stitch 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "ADD1,ADRB2,AGT,AMPH,BIN1,ANK2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,KRIT1,LRBA,CACNA2D2,CHRM1,SNAP91,DMD,DMPK,EDN1,EDN3,EDNRA,CACNG7,CACNG3,CACNG2,PRKAG2,ATP2C1,GCNT2,MYH6,NUMA1,ABCB1,PKD1,PRKACB,PRKCB,PRKCG,QDPR,GLDN,RYR1,RYR3,CASC3,ADHFE1,MGRN1,TPCN2,TRH,KCNAB1,SSPN" Drug 3432_UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "SRPX,DOC2A,APBA2,APC,PDE8B,ATP6V0A1,CFLAR,ARHGEF7,C5,CA4,CLGN,CACNA2D2,PICK1,RCHY1,CNTNAP2,DZIP3,GPRASP1,DTNA,HIPK3,ACSL4,KAT8,FGFR1,PDLIM5,TRAF3IP2,GCNT2,GLYR1,KLF12,KCNJ3,KHK,MBD1,MIA2,KITLG,MX1,LYRM9,NEUROD1,NPR2,PDE3B,PLXNB1,PTHLH,FAM120C,RAB5B,RGS3,SYNDIG1,ZNF821,SCMH1,WDTC1,CLSTN2,PLCB1,IQCE,PCDHA6,TK2,ZMYND8,ZNF45,SPHK2,SLC30A3,WNK1,SCG2" Drug 6868_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "ALCAM,BEGAIN,AMH,BRINP2,RGS11,BCL7A,CACNA1I,CA4,CACNA2D2,CHRNA4,RAB28,STOML1,DNAJB5,WHRN,CRY2,CSF1R,VCAN,RABGAP1L,SLC12A6,EGFR,RASGRP2,F3,AGAP2,SEMA4D,PDLIM5,USP19,SPACA9,ADAMTS13,GUCY1B1,MITF,NF1,SLCO1C1,PALM,PTAFR,PTHLH,ZSCAN32,C1orf54,ZDHHC14,RNASEL,RPS6KA2,SLC22A4,SNCA,KDM4B,ZCCHC24,IQSEC2,TSPYL2,MAPK8IP3,VPS13A,ATP11A,TCF4,PCDHA6,R3HDM1,ZKSCAN5,KCNK12,SEMA3B,NAV2,SSPN" Drug 4108_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "ASPHD1,ALCAM,ALK,AMPD3,GAS7,ATP2B2,CACNG1,CLGN,TAOK2,WHRN,ABCG1,AATK,SNCAIP,PLCH2,PDE4DIP,EXOG,ATN1,ENO2,EPHB1,CACNG2,CSPG5,GAB1,RND1,GNAO1,BTN2A1,GSTM5,ATXN2L,HLF,ICA1,ITGA7,KCNK2,KCNMA1,KCNN1,LSS,MATN3,ADAM22,OMG,PALM,LRP12,PACSIN1,MAPK7,PTAFR,RGS10,SCG5,SH3BP2,DOCK10,LIMCH1,POPDC3,KIAA1107,SZT2,HIF3A,TEX15,TRIO,LAT2,SLC30A3,NAV2,SLC17A7" Drug 2567_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "NDRG2,PPFIA4,APC,FAM131A,CDK5R1,MTMR3,FOXN3,TPP1,CPS1,SGSM2,CDON,SEZ6L2,EEF1A2,CELSR3,FAM13A,SORBS3,ELN,ENO2,LRRC23,PIPOX,DLC1,ST3GAL6,FGFR1,PDLIM5,OGA,GABRA4,SEPT9,GNG3,NCKAP1L,ATXN2L,IL11RA,ITGA7,MEF2C,AFDN,CNOT4,OLR1,CCSER2,PTCH1,CEP97,SH3BP2,CNKSR2,SLC2A5,EPN2,SLC6A8,BTBD7,IZUMO4,SPTAN1,PDLIM2,TCF7L2,CRTC1,TNS1,TPM1,FLRT2,TRIM9,MAP3K12,PCBP4,FAM13C" Drug 3807_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "MRTFA,BCAS1,LGR5,CDC14B,ARHGDIG,ASCL1,CCDC181,CADM3,ADAM23,RGS9,RUNX1T1,NEURL1,SULT4A1,RAB26,AATK,PDE4DIP,MAGI2,SMG7,HS3ST2,DRD1,DTNA,EGR3,IGSF6,FGR,AGAP2,CAMKK2,ZNF44,CPLX2,RND1,GRK4,STMN2,GRIK5,GRM7,HLF,ICA1,KCNN2,ADAM11,KITLG,AFDN,CD200,GPR85,POU3F2,PPP2R2B,PRKCB,KHDRBS2,RGS4,PKNOX2,MAPK8IP3,AJAP1,VAMP1,ARC,ZFPM2,SEZ6L,CADM1,WIPF1,LAT2,ZNF154" Drug 6809_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-07 4.42E-02 2.38E-05 2.71E-04 57 193 "AP2A2,AGT,BIN1,AQP6,PPP4R4,SLC2A11,CACNB4,CACNG1,ARHGEF1,NEURL1,TAOK2,ARMC8,NCOR2,CHD5,RIMS2,DCAF4,TOX,RIMS3,ST8SIA3,EPB41,CDKL3,FLT1,POLL,GNAS,GPR37,GRM1,GUCY1A2,ICA1,KCNN2,VWA5A,MID1,ZNF862,NPPA,CDK14,PURG,PPARA,MAPK7,PTHLH,RGS4,TCP11L1,SEMA6D,SELL,FAM214B,KANSL3,SLCO1A2,MAPKBP1,ZCCHC24,SPP1,AJAP1,SYN2,RPGRIP1L,PCDHGA1,SPX,UCHL1,HPS4,SLC17A7,ITM2C" Drug 6919_UP scriptaid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.16E-07 4.49E-02 2.41E-05 2.75E-04 55 184 "ABAT,ADRB2,KIDINS220,NME5,ARNTL,ST3GAL5,CLCN3,SLC4A7,ABCG1,OSBPL3,PDE4DIP,CTH,RIMS3,DNAJC6,ANKRD46,F3,TBC1D16,ATP8A1,FDFT1,BAIAP2,DPYSL4,PDLIM5,FYN,GLS,RAB40B,AGFG1,KIF5C,L1CAM,LSS,MMP16,PDGFRA,SERPINE2,SERPINI1,PRKACB,ELOVL2,PTPRH,RBBP6,RGS4,RPS6KA2,SEC14L1,WDR47,ELMO2,PALLD,KDM4B,DOP1A,ARHGAP26,THSD1,ELOVL4,RGL1,SYT11,SYT1,ANKRD12,TGFBR3,DNAJC12,PLSCR4" Drug 3941_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,ADCYAP1R1,ADORA3,PLA2G6,SEMA6A,BEGAIN,ADAM23,P2RX6,CDH2,LHX2,LY86,NCOR2,DNAH9,SHANK1,DYRK1A,EDNRA,RASGRP2,KCNMB2,IGSF6,REEP2,PTK2B,CSPG5,NEU3,LYVE1,POLL,STON1,GRIK5,KLF12,HLF,KCNK2,NCAM1,NEUROD1,CNOT4,POU3F4,ELOVL2,C1orf54,KCNIP1,RYR1,STUM,RASA3,FRMPD1,ASAP3,SLITRK3,SLC1A7,PKNOX2,SLC8A1,LIMCH1,PDZD2,NMNAT2,HECW1,PLCB1,ATP11A,CUX2,DOCK9,PIK3R5,UGT8,FLRT2,PARP11" Drug 5948_UP rotenone; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,NME5,MRTFA,LGR5,ATP2B2,KIF1A,SYNJ2,SCAPER,MYRF,HAP1,MAP7,USP2,SCARB1,ARMC8,HAPLN1,DZIP3,GIT2,DMPK,SIDT2,TNK2,PNMA2,OGA,ERAP1,GLI2,POLL,ATF7,GRM7,PADI2,TJAP1,MAPT,MITF,NPR2,PCBP3,PFKFB3,SPATA6,TNPO2,MAPK8,GRAMD1C,FAM120C,FRMPD1,DOCK10,SLC6A9,ZNF667,RBM34,ARHGAP26,SPTB,MAPK8IP3,MLC1,EXOC7,SMG6,SZT2,TK2,TRIO,HPS4,SEMA3B,MVB12B,EPM2A,TIGD6" Drug 3801_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SLC12A5,NR0B1,ADGRB2,BMPR1B,BAIAP3,USP2,CD86,CDO1,CHI3L2,TAOK2,RAB33A,KIAA1549L,HAPLN1,CSF1R,NOS1AP,DSCAM,ABCC9,EDNRA,MBNL2,EPB41,SORBS1,PDLIM5,SIGLEC8,GATM,GFER,GLI2,GNAL,LILRA2,GPR17,TPPP,GRM1,ICA1,VWA5A,CD200,MYT1,NCAM2,NF1,SLCO1C1,NPTX2,KCNK10,PDE2A,CAMKV,PPARA,GDPD2,SUSD4,SLC2A5,PKNOX2,SLC11A1,SLC12A4,SORCS3,SCN3B,SOX2,SOX15,RBM26,LMO3,TAL1,UCHL1,SLC17A7" Drug 6013_UP Tiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "LTBP4,ANK3,KCNAB2,APBB2,GAS7,CADM3,N4BP2L1,CFLAR,CACNA1G,CAMK2B,KCNAB3,CHN2,SULT4A1,FHL5,TCEAL2,VCAN,RIMS2,DTNA,EDNRB,DLC1,DCTN2,FYN,HBS1L,GAP43,ATP8A2,GNAO1,PCLO,GRB10,ITGA7,KCNMA1,VWA5A,MAP4,AFDN,NPY,NTRK2,RETREG1,GRAMD1C,PTPRO,ZDHHC14,RAVER2,TCP11L1,SH3BP2,ASAP3,SYBU,DZIP1,FAM214B,SOX10,NMNAT2,PEG10,ATP10B,SYT5,DICER1,AP4E1,THRA,RUNDC3B,UCHL1,LAT2,NUP214" Drug 2171_UP Deltaline [6836-11-9]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SYN3,NDRG2,SRPX,ALK,CDC42BPA,APBB2,PDE8B,ALDH4A1,ADGRB1,MTMR3,THSD7A,MAGI1,B4GALT6,TAOK2,CABP1,NRG2,PDE4DIP,RIMS2,CTIF,MYEF2,HIPK3,PLXNC1,SORBS3,C3orf18,ERBB2,ZMYND11,TMEM8B,ATP8A2,ALDH1L1,POLL,STON1,KCNN1,MBNL1,CD200,MPP2,NTRK2,PFKFB4,PLCL1,SUSD4,RASGRF1,SEMA6D,SLC1A3,RPH3A,EPN2,PKNOX2,SLN,TNIK,LHPP,ACSBG1,TACR1,LMF1,KLC2,MAP3K12,GDPD5,STMN4,PRDM10,FAM13C,JPH3" Drug 2228_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NME5,BIN1,SEMA7A,GAS7,ADGRB2,CFLAR,CACNA1G,BAIAP3,ADGRG1,FOXN3,CHM,CHN2,TAOK2,STOML1,QKI,SULT4A1,CNTN1,TCEAL2,DOCK4,MAML1,DLG3,DMPK,EDN1,SPEG,C1orf61,AGAP2,DLL3,CPLX2,LYVE1,RND1,NR3C1,ITIH2,TAGLN3,NF1,PFKFB2,PLCD1,LRP12,CEP41,MAPK7,PTAFR,C1orf54,ASIC4,PPP1R9A,SH3GL3,RPH3A,ARHGEF40,SLC9A5,LIMCH1,NPAS3,POPDC3,SZT2,CRTC1,PCDHA5,DNAH7,DICER1,KCNK12,XRCC4,MVB12B" Drug 6725_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ASIC1,ADRA1D,MRTFA,CDC14B,ARHGDIG,PDE8B,ATP2B2,KIF1A,ADAM23,LDLRAD4,SEPT7,DNAJB5,VCAN,CNTNAP2,CTNND2,BRINP1,CDON,FCF1,AASS,ING4,MTSS1L,EZH1,F3,SORBS1,PDLIM5,TRAF3IP2,SIGLEC8,STON1,LPAR4,NEUROD1,NF1,PDE4D,PIK3R1,EPN1,TNPO2,PRKAR1B,RAP1GAP,MAP6D1,PAQR6,FOXRED2,FRMPD1,FBXO11,SNCA,TSNAXIP1,BEX1,ARHGAP26,RBM26,MAPK8IP3,THRA,TNS1,VIPR2,LMF1,WIPF1,XRCC4,EVI5,NUP214,ACTR3B,AAAS" Drug 6089_UP Althiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NLGN4X,SEMA6A,AQP6,SEMA4G,CDK13,BAIAP3,CDO1,LY86,IFFO1,SNCAIP,CYBB,SPOCK2,SRGAP3,USH1C,HEYL,RCAN2,LRRC23,ABCA8,TUBB4A,ZMYND10,ZNF44,SIGLEC8,GATM,SRCAP,GLYR1,PRUNE2,ATF7,STON1,ADAMTS13,GRIK5,NR3C1,GRM7,HTR5A,IRF8,C2orf72,KCNMA1,KIT,MGAT3,ADAM22,MSR1,ZNF862,MYT1,NNAT,OGG1,PDE4A,C19orf57,MAPK8,RELN,PNMA8A,HKDC1,SLN,LIMCH1,SOX10,ARHGAP26,PHLDB1,SYT5,TRIO,ADAMTS9" Drug 3190_DN Fendiline hydrochloride [13636-18-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SEMA6A,MRTFA,CDC14B,SEMA4G,SLC4A4,ATP6V0A1,CFLAR,CA12,SOCS6,CSF1R,CYBB,TBC1D5,ELAVL3,VPS26C,F8,SEMA4D,ANKFY1,GAB1,ZNF44,USP19,TXNL4A,MSL3,GPR19,SPACA9,KCNJ3,KIF5C,MATK,ADAM22,NF1,CAMKV,PRKAR1B,CEP97,RGS10,RGS12,CCDC25,ROM1,FBXW7,EMID1,SLC1A7,ZKSCAN3,SMARCD3,KIF13A,SEPT8,ACSBG1,VAMP1,EXOC7,DOCK9,TMEM121,ZNF34,SLC44A1,TMOD1,CABIN1,ZMYND8,VIPR2,SPHK2,TFIP11,EPM2A,SSPN" Drug 4013_UP Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,ADD2,AMPH,APBB2,PPP4R4,ARSE,AZGP1,CFLAR,SCAPER,MTMR3,LDB2,SCARB1,CHM,TAOK2,TPP1,ENTPD4,SUSD5,EDRF1,SEC14L5,TRAPPC9,DTNA,HIPK3,CELSR3,EIF4G2,EPHA5,ZNF391,HPCAL4,PRELID3A,GFRA1,GPR17,GRIK5,CACFD1,GSTM5,KCNJ3,KCNN1,MMP16,NEFM,NF1,NTRK2,PMS2,PPARA,LRRN3,PKN2,MAPK4,BEND5,ZMAT4,CSRNP3,ASIC4,CNKSR2,SLA,SLC11A1,OGDHL,ZSWIM8,NPAS3,EXOC7,R3HDM1,TNS1,PHTF2" Drug 5983_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,GAS7,APP,ASCL1,PTCH2,ALDH4A1,SCAPER,RUNX1T1,CBFA2T2,CDH10,CRY2,CRYM,VCAN,PDE4DIP,DBN1,RUSC2,DUSP9,EDNRA,EFNB3,C3orf18,COQ7,KCNMB2,EZH1,DLC1,FOXG1,EFCAB2,GAB1,TMEM8B,SEPT9,ATF7,LILRA2,GRIK5,INPP5B,KCNJ5,KITLG,NELL2,NNAT,NPPA,PCSK1,PFKFB2,SERPINE2,MTRF1L,LRP12,RAB3IL1,TRIM68,RGS4,PNMA8A,LRRTM4,SUPT20H,RASA3,SH3GL3,SLC20A2,ATP10B,PLCB1,EXOC7,ZEB1,TMOD1,ITM2C" Drug 6154_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADCY6,PLA2G6,APOC1,CDC14B,MYRF,CA8,MAP7,DLGAP2,CHRNB2,TCEAL2,PDE4DIP,DGKG,SV2B,DLG3,DMD,ATN1,DYRK1A,SNX29,EFNA3,DMTN,RASGRP2,ETV1,F5,FGFR1,BAIAP2,CAP2,AGAP2,FLNC,GAB1,GCNT2,GFER,GFRA1,LILRB4,GPR19,PCLO,ICA1,KCNB1,KIF5C,NINJ2,NOS1,CLDN11,DUSP26,CAMKV,PKIA,NEK11,EMID1,EPN2,LIMS2,PKNOX2,FAIM2,ARHGAP26,RBM26,FAM168A,TRIM2,CRTC1,PARD3,VAV2,SPHK2" Drug 6146_UP Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "BIN1,DDX3Y,PROM1,MYRF,THSD7A,HAP1,HIP1R,RUNX1T1,CBFA2T2,SYNGR3,CHRNA4,SLC24A2,CABP1,CSF1,RIPOR2,SNPH,PARD6A,DLG3,DMPK,USH1C,SGK2,OPTN,MBNL2,DMTN,LRRC23,RASGRP2,ERBB2,RASL12,ATP8A1,KAT8,FGF1,C1orf61,KHDRBS3,GATM,KCNMB4,PRUNE2,WIF1,KCNN1,MSR1,NOS1,EPN1,POU3F4,PRKAR1B,RELN,KLK6,BCAS3,RET,KCNIP1,RYR1,FERMT1,NTNG1,SLC11A1,FAIM2,TMCC1,ASTN2,WSCD1,PCDHGA10,SEZ6L" Drug 7293_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SERPINA3,KCNAB2,APP,CFAP410,PLEKHB1,DNAJB5,PICK1,IFFO1,HAPLN1,CSF1R,PDE4DIP,SDC3,HDAC9,JAKMIP2,EFNB3,CELSR3,TESK2,TRMO,TDRKH,AP4S1,GUCY1A2,ATXN2L,INPP5B,MOBP,NF1,PFKFB4,PIK3R1,PPP5C,CNTLN,PEX5,TMEM231,CCDC40,ARHGEF10L,SEC61A2,ZNF671,PAQR6,HSPA4L,SCG5,DOCK10,AMBRA1,RPH3A,SLC1A7,SLC6A9,SHANK2,SNCA,WDTC1,DDN,LHPP,MAPK8IP3,SYT11,KAZN,ADGRL3,SYNE1,AHCYL2,TIAM1,CABIN1,OSBP2,KCNAB1" Drug 3928_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "KIAA1324,APAF1,N4BP2L1,CACNA1I,KALRN,CAMK2B,P2RX6,DCLK1,JAM2,STOML1,LY86,SNCAIP,OSBPL3,CNTNAP2,C2CD2L,SPOCK3,NTM,DYNC1I1,DRP2,ABCC9,FAM13A,MTSS1L,ERCC2,CORO2B,DLC1,FGFR1,GAP43,POLL,GRIA4,AP4S1,KLF12,TJAP1,L1CAM,NCAM1,KCNK10,CAMKV,PURG,PPP2R2B,SAMD9,GAL3ST4,SYNDIG1,PKNOX2,SNCA,FAIM2,PDZD2,ZBTB43,SYT11,JMJD6,DOCK9,CHST5,AMACR,UBE3A,FLRT2,ZNF225,SLC30A3,SLC17A6,TIGD6,AP3B2" Drug 7232_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,NDRG2,AMPD3,GAS7,PPP4R4,CAPRIN2,RASL11B,ATP1A3,BTRC,CA4,CAMK2B,ARHGEF2,ADGRG1,TAOK2,DNAJB5,CSF1,CYBB,CTIF,SMG7,FRY,TNK2,KIAA1109,FHL1,C1orf61,GART,ALDH1L1,HNMT,INPP5B,KIT,KPNA5,MAN2A2,KITLG,MITF,NEK1,NF1,CNOT4,PCDHGC3,PLCD1,PPP5C,MAPK8,PEX5,RGS10,ZFHX4,SCN8A,ZNF821,SYBU,RCOR3,ZNF415,LHPP,SZT2,PHF24,SLC19A3,PCDHA6,PCDHA5,GPR161,TMOD1,TPM1,EPM2A" Drug 4999_UP Bezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,APC,CDC14B,RGS20,SLC4A4,ALDH7A1,CFAP410,CAMK2A,CDH10,SULT4A1,LY86,AKAP7,ABI3BP,IFFO1,PDE4DIP,SRGAP3,EXOG,HS3ST2,CDON,SIDT2,EFNB3,PLXNC1,SORBS3,CDKL3,CORO2B,FHL1,GAD1,HBS1L,B4GALNT1,ALDH1L1,GCNT2,STON1,GRIK5,CACFD1,IRAK3,NXPH3,ICA1,SHISAL1,C2orf72,KCNQ3,P2RY1,PCDH9,MBOAT7,LRRN3,RGS3,ASIC4,SNCA,DOK5,PEG10,MAPK8IP3,SYT11,POPDC3,TACR1,PCDHGA10,THRA,KCNK12,NT5M,SEMA3B" Drug 6034_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SYN3,ACTN2,SEMA6A,TRMT9B,DDO,MARK4,CALB1,CAMK2B,DLGAP1,CHRNA4,RAB33A,SH2B1,NCOR2,SNCAIP,CNTNAP2,RUSC2,SPOCK3,DMPK,DUSP9,EFS,FGF1,FGFR1,DCTN2,KHDRBS3,B3GAT1,ZNF44,SIGLEC8,PRUNE2,LPAR4,TPPP,HRH3,HLF,HNMT,TJAP1,KCND3,VWA5A,MAOB,MEF2C,NCAM1,NPPA,PDE1C,CDK14,PURG,MAPK8,RGS12,EMID1,SCN8A,ASIC4,SLC1A7,LIMCH1,PEG10,SPART,RPGRIP1L,SEZ6L,TRH,UCHL1,LAT2,DNALI1" Drug 2304_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADCYAP1R1,ADORA1,ADORA2A,ADRA1D,ANK1,ATP2A2,CADM3,GYG2,SGCE,CD86,CBFA2T2,MYOM2,CRLF1,CHRNB2,TAOK2,SLC24A2,AKAP7,TCEAL2,NRG2,GREB1,SEC14L5,SNPH,SPOCK2,NRN1,OLFM1,FGFR1,GNAO1,STON1,GPR22,GRIK2,GRIN1,GRM3,MAP2,ADAM22,MYH7,MYT1,PDE1C,PACSIN1,PTAFR,PTPRN2,ZSCAN2,C1orf54,CNKSR2,PKNOX2,CXXC4,SNCA,KDM4B,TNIK,SOX10,HECW1,SPART,TEX15,GPR161,THBS4,TNS1,SEZ6L,CLIP2,SLC17A6" Drug 3738_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ASIC1,AP2A2,C1QTNF3,APC,APP,CDK13,ADGRB2,TAOK2,CNTN1,NRG2,NCOR2,AATK,PDE4DIP,SLITRK5,CNIH3,SMG7,AK5,CHRDL1,ATN1,RCAN1,SGK2,FCF1,RBM12,EIF4G2,ELAVL3,FGF1,C1orf61,PDLIM5,DISC1,GLYR1,GRIK5,KLF12,KIFC3,LMO2,VWA5A,NF1,NFIX,PIK3CD,RC3H2,FSD1,MAPK7,MAPK8,RGS10,DZIP1,OGDHL,ZNF415,TSNAXIP1,DDN,CEP68,PHLDB1,DOCK9,CRTC1,CHST8,GPR161,THRA,TK2,UGT8,LMF1" Drug 3723_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,ASPHD1,NDRG2,NR0B1,EPB41L5,GAS7,NRP2,BMP7,SYNJ1,CFAP410,CAMK2B,RUNX1T1,SYNGR3,CHI3L2,TPP1,MAGI2,DTNA,ST8SIA3,CELSR3,EGFR,OLFM1,CAMSAP1,HPCAL4,FYB1,B4GALNT1,GNAO1,GRIK1,HTR2A,KCNH2,LSS,MOBP,NF1,NNAT,PALM,PDE2A,MTRF1L,PRKAR1B,PTN,RGR,RGS3,RGS4,RGS12,RNASEL,GSTCD,EMID1,RASA3,NTNG1,SOX2,SPTAN1,VAMP1,SYN2,SYT5,TLR4,CADM1,RPRM,LAT2,XRCC4,NUP214" Drug 3711_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADORA1,PLA2G6,LTBP4,GAS7,BMP7,CACNG1,RUNX1T1,CD86,CDH8,SULT4A1,LRIG1,SPOCK2,BRINP1,TRAPPC9,EGFR,TNK2,HPCAL4,AFF2,DCTN2,ZNF44,GAD2,IQGAP2,SIGLEC8,GNG3,GRIK2,GRIK5,GRM2,SHISAL1,TJAP1,KCNJ4,KCNN1,KIFC3,LSS,ADAM22,LYRM9,NNAT,NPPA,OLR1,MASP1,PTAFR,KCNIP1,SEMA6D,PKNOX2,SLC15A2,FAIM2,NFASC,PCDHGA1,FAM189A1,SEZ6L,ZMYND8,PDIA2,FLRT2,SLC13A3,ZIC3,REEP1,SLC30A4,PRDM2,NUP214" Drug 4818_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ABHD6,NDRG2,C1QTNF1,SEMA6A,ARNTL,BAIAP3,SPAG9,CBFA2T2,ADGRG1,CLU,DNAJB5,SLC4A7,TCEAL2,BAG4,ENTPD4,VCAN,CTIF,DCT,RUSC2,LYPD1,DMPK,DTNA,EDNRA,HIPK3,EFNA3,ING4,KAT8,AGAP2,FLNC,ANKFY1,SORBS1,MALT1,GLYR1,GRB10,NR3C1,RASSF8,LSS,CD200,BCO1,MX1,NFYA,NPTX1,TNPO2,C1orf54,SUSD4,TCP11L1,STUM,SH3BGR,SMTN,SMARCA4,ZHX3,EXOC7,KIAA1107,PCDHA6,ZMYND8,VAV1,NSD2,WNK1" Drug 4638_DN Dioxybenzone [131-53-3]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ASIC1,TRMT9B,AMH,AMT,APOC1,PDE8B,ATP1A3,BAIAP3,KRIT1,REPS2,CDH10,CHI3L2,B4GALT6,CLCN4,IQCK,CNTNAP2,SLITRK5,CHRDL1,ATN1,DTNB,CELSR3,MBNL2,AASS,MRNIP,MTSS1L,FGFR3,CINP,SIGLEC8,ZNF276,COPS8,MSL3,GPD2,GPR17,L1CAM,LIG4,NEUROD1,NNAT,OPCML,PAK3,PTN,PTPRB,PTPRE,PID1,RGS10,SLA,SLC1A7,SLN,TSNAXIP1,KIAA1107,THRA,TK2,BEX4,TNS1,LMF1,ZNF711,SEMA3B,KAT6A,TIGD6" Drug 6625_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADORA1,KIDINS220,MTUS1,ALK,EPB41L5,CCDC181,ADAM23,SYNJ1,BTRC,CDH10,ARHGAP33,CACNA2D2,ENTPD4,PDE4DIP,CNTNAP2,PPP1R16B,DCT,C2CD2L,RASGRP2,CEND1,ABCA8,FOXG1,DCTN2,B3GAT1,ALDH1L1,PCDH17,GRIA1,PADI2,VWA5A,MAN2A2,MAOB,NELL2,CNOT4,NTRK3,OPCML,PCDH9,PDE4A,PDE4B,PKN2,MAPK10,C1orf54,EMID1,IL17RB,ASAP3,OGDHL,KIF13A,SP4,HECW1,BEX1,SPTAN1,ZEB1,TMEM151B,RUNDC3B,CADM1,FLRT2,LAT2,KCNK12,PARP6" Drug 4382_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NDRG2,KIDINS220,KIAA1324,SEMA6A,LTBP4,BIN1,AQP4,BRINP2,KIF1A,CACNA1I,BAIAP3,CDC42,LHX2,CLCN4,HOMER3,SNCAIP,MICAL2,RIMS2,RUSC2,RABGAP1L,EDNRB,EIF4G2,TNK2,PIPOX,DLC1,DISC1,GCNT2,PRUNE2,GRK4,INPP1,MMP16,MYO7A,NF1,NOS1,PLCB2,EPN1,PTAFR,PTX3,RAB3A,RAD52,C1orf54,ZMAT4,TRIM68,RGS10,ZFHX4,TCP11L1,FAM214B,SNCA,FAIM2,WSCD1,PCDHGB6,CRTC1,CHST8,TMOD1,PIK3R5,TRIO,ZNF711,PARP11" Drug 2486_UP Trimethadione [127-48-0]; Up 200; 28uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,MTUS1,AMH,BIN1,PKP4,APC,MPDZ,BTRC,CFAP410,CACNA2D1,THSD7A,HAP1,SLC16A4,CDO1,CACNA2D2,COL9A3,AKAP12,EDIL3,FER,FGF13,AGAP2,DCTN2,FOLR2,SIGLEC8,PCDH17,HPGDS,GPM6A,GPR22,CACFD1,KCNJ3,KCNJ5,KIFC3,LAMA2,MAP4,ADAM22,MSR1,NCAM1,NINJ2,PCDH8,CDK14,SPATA6,CEP41,RELN,PTPRH,PTPRN2,TCP11L1,RYR1,SLC20A2,SLCO1A2,RIMS1,SNCA,TMCC1,SOX10,HECW1,PEG10,CLSTN2,TMOD1,STMN4" Drug 4023_DN Metronidazole [443-48-1]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADORA2A,LGR5,PDE8B,ATP2B3,ARHGEF7,CACNA1A,CHI3L2,NRXN3,DNAJB5,HOMER3,CRMP1,AATK,CSF1,CNTNAP2,RUSC2,SGSM2,DMPK,ATN1,CNNM1,SORBS3,MRNIP,ETV1,FCGRT,AFF2,GABRA2,GCNT2,GFER,POLL,TDRKH,GRM8,GUCY1A2,ICA1,SHISAL1,ITPKA,VWA5A,GIT1,CNOT4,PAK3,PBX1,EPN1,PTN,ATXN7,ANKRD6,FAM214B,SMARCD3,IFT122,SPTB,DDN,MAPK8IP3,ARC,DOCK9,NSD1,TIMP4,RPRM,NT5M,EVI5,KAT6A,NUP214" Drug 6748_UP Bisoprolol fumarate; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,MTUS1,PLA2G6,OGT,PKP4,EPB41L5,MTMR3,RUNX1T1,CDC42,FOXN3,SH2B1,CSF1R,CNTNAP2,FAM131B,PHYHIP,MFAP3L,C2CD2L,HIPK3,ELAVL3,COQ7,NRN1,ST3GAL6,FGFR3,IQCG,GABRA2,GATM,ALDH1L1,GNAL,ADAMTS6,ELOVL5,KCND3,KCNF1,ADAM22,MX1,NF1,NPPA,ENPP2,RETREG1,SPATA6,MAPK8,PSD,TMEM231,ZFP30,DOCK10,NTNG1,ZNF334,KIF21B,IQSEC2,CEP68,SYT5,TAL1,PCDHGA10,VSNL1,MKRN3,SPHK2,EMSY,KCNAB1,EPM2A" Drug 2432_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SLC12A5,KIDINS220,DOC2A,APBB2,KIF1A,CACNA1I,CACNA2D1,CACNB2,CHGA,CHM,CHN2,ZFYVE9,NCOR2,MICAL2,OPTN,OLIG2,DCTN2,TRAF3IP2,SRCAP,GLYR1,PRUNE2,GPM6B,SOX21,PADI2,TJAP1,LAMA2,MAP4,NPPA,NRCAM,NTRK3,PDE4D,FSD1,PPARA,PRPH,BCAS3,PTAFR,RFX2,RGS12,ZFHX4,TCP11L1,SH3BGR,SLC14A1,SORCS3,SNCA,ATP10B,PHLDB1,WWC1,RPGRIP1L,PCDHGA10,TIAM1,TK2,RBFOX2,CHST5,ZMYND8,UGT8,NT5M,SLC17A7,PLSCR4" Drug 2149_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "AP2A2,APC,GAS7,CDK13,ASPH,NCOA1,BCL2L2,SYNJ2,CAMK2G,ARHGAP33,ZFYVE9,ZNF337,DGKG,EXOG,ABI2,RASGRP2,TESK2,AFF2,TRAF3IP2,GAD2,INPP5K,CRCP,POLL,GPR19,KCNJ5,VWA5A,MIA2,GIT1,MX1,NF1,SLC11A2,ODF2,PMP22,RAB3IL1,RGS3,RGS10,MYH14,SH3BP2,BTBD7,ARFGAP1,KDM4B,WDTC1,ZCCHC24,FNBP1,DOK5,IZUMO4,DBNDD2,NSFL1C,KAZN,KIAA1107,TCF7L2,NSD1,TMOD1,PARD3,TNS1,RBFOX2,ZBTB14,ZBTB38" Drug 7506_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NDRG2,AMH,CDC42BPA,APC,ALDH4A1,SLC4A4,N4BP2L1,CFLAR,ASIC3,SH2B1,PDE4DIP,JAKMIP2,DSCAM,DTNA,DTNB,HIPK3,PHF20L1,MBNL2,HSD17B14,SPEG,ZIC4,EFEMP1,ZNF589,FECH,FER,FGFR1,SCARA3,GALC,SEPT9,MALT1,MSL3,ITPKA,JAK2,KCNJ3,L1CAM,MIA2,MMP16,ADAM22,EPN1,PACSIN1,PPP5C,MAPK7,CARF,TCP11L1,ATXN2,SLC1A2,ZNF365,SLN,TTC17,ZCCHC24,IZUMO4,MAPK8IP3,ATP11A,TRIM2,SSBP2,ZKSCAN5,ZNF45,GAN" Drug 6889_DN AG-012559 [369370-06-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "LTBP4,BIN1,CDC42BPA,APBB2,FAM131A,APP,PPP4R4,ALDH7A1,C5,CFAP410,HAP1,CAMK2G,USP2,SOCS6,PLEKHB1,TAOK2,STOML1,SULT4A1,CSF1R,FAM169A,GPRASP1,DCAF8,MFAP3L,DTNA,ING4,ERCC2,DENND4A,MALT1,HPS5,ATXN2L,HNMT,INPP5B,JAK2,IPO5,MIA2,NF1,SLC11A2,PCDH9,RETREG1,STRN3,SUPT20H,PPP4R3A,MAPKBP1,RBM34,KDM4B,DOP1A,SS18,ARC,ASTN2,ANKRD12,EXOC7,KIAA0930,TNS2,TMOD1,WNK1,GDPD5,SEMA3B,SSPN" Drug 3891_UP Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ASIC1,NDRG2,ALCAM,ASPH,NRP2,MTMR3,CACNA1I,CAMK2B,CH25H,ARHGAP33,TAOK2,CLCN4,CRMP1,CNIH3,TMCC2,CDON,EIF1,EN2,F5,FGFR3,AFF2,PDLIM5,CSPG5,GFER,PCDH17,GLYR1,GRK4,GRIK5,GRM7,KLF12,HTR2A,ITIH2,KCNK2,MATN3,MEF2C,AFDN,MPP2,NOS1,CLDN11,CDK14,PNMA3,CEP41,PTAFR,SH3GL3,EPN2,KDM4B,PEG10,SPTAN1,ATP10B,ABCC8,ROBO3,WSCD1,HEY2,TRH,TRPM2,VAV2,PHTF2,ADAMTSL3" Drug 4480_UP Dacarbazine [4342-03-4]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "KIDINS220,PLA2G6,MRTFA,AMH,PPFIA4,APAF1,CDK13,ATM,ALDH7A1,ADAM23,CFLAR,FUBP1,CFAP410,CHI3L2,STOML1,AKAP5,CYBB,RIMS3,EXOG,ING4,RGS17,OGA,FYN,GLRB,PRRC2B,GPM6A,GRIK5,GRM7,ICA1,SHISAL1,JAK2,SMAD1,SLCO1C1,GPR85,PMS2,MAPK7,PROX1,PTPRH,PTPRN2,RGS4,ROM1,KCNIP1,SH3BGR,FBXO11,RPH3A,PKNOX2,ZNF334,SLCO1A2,SOX15,VAMP1,MCF2L,KIAA1107,TRIO,RUNDC3B,LAT2,SPHK2,ZBTB38,ZNF225" Drug 3554_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,BIN1,APC,ALDH7A1,RGS11,LDLRAD4,ARHGEF2,RCBTB2,EPS15L1,TPP1,ARHGEF6,SNCAIP,CHD5,CNTNAP2,SDC3,SEC14L5,RIMS3,CTIF,SPOCK3,DRD1,DSCAM,EFNA3,ERCC2,EXTL1,ST3GAL6,KIAA1109,FGFR1,GABRA2,GAD1,GAP43,DISC1,MSL3,RAPGEF1,SPACA9,ADAMTS13,ITPKA,KIFC3,NF1,OPCML,PRODH,PTCH1,RGS12,CARF,ABLIM3,SLC11A1,SNCA,SPTAN1,ATP10B,PHLDB1,AJAP1,VPS13A,PLCB1,TAC3,GPR161,SEZ6L,ZFP37,SEMA3B,NUP214" Drug 3929_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADORA1,ADORA3,C1QTNF1,DOC2A,APAF1,CADM3,MTMR3,CLGN,LY86,CRY2,VCAN,DCAF4,NOS1AP,CYBB,DCT,ST8SIA3,TNK2,ELN,MTSS1L,ERCC2,FGFR1,FHL1,DCTN2,FOLR2,NSG1,GABRA5,SRCAP,LYVE1,KCNC1,MAG,MBP,MID1,CD200,MSI1,PCBP3,NTRK2,OGG1,PDE4A,C1orf54,RFX2,STUM,SH3BP2,SLITRK3,CNKSR2,PKNOX2,SHANK2,SLCO1A2,RIMS1,FAIM2,PDZD2,WDTC1,UNC5B,SSTR2,ABCC8,MICAL1,ZIC3,SLC30A3,DPF3" Drug 5789_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACHE,ADD2,ADRA1D,NME5,PLA2G6,BIN1,SLC4A4,PROM1,SYNJ2,RUNX1T1,NEURL1,ARHGAP33,WHRN,NCOR2,FRMPD4,SPOCK2,EXOG,EDN1,EDNRA,CNNM1,ZNF549,FLT1,DCTN2,PRELID3A,GLI2,POLL,LILRA2,GPER1,CACFD1,GRM1,GRM7,JAK2,KCND3,MAPT,KITLG,MYH6,PDE3B,LRRN3,PRKCB,RAB3A,RAB3IL1,C1orf54,RASGRF1,MYH14,KCNIP1,RASA3,BCAN,SLC1A7,PKNOX2,SLN,OGDHL,FAIM2,HECW1,DOCK9,SLC19A3,TRIO,PRDM2,KCNAB1" Drug 5628_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "GAS7,CCDC181,AZGP1,CFAP410,CA8,CACNA2D1,HAP1,CCK,CLCN4,LY86,CNN3,WHRN,CTIF,DMPK,ATN1,HIPK3,EN2,ERBB4,ERCC2,SPEG,SORBS1,GAP43,GPR162,ADAM28,PRUNE2,PCLO,SPACA9,GUCY1B1,KIF5A,MAOB,LRP1B,MEF2C,MMP17,MX1,NEFM,NELL2,NNAT,NPR2,NPTX2,CDK18,PLCD1,PURG,PNMA3,LRRN3,MAPK8,TRIM68,KCNIP1,SH3GL2,PKNOX2,KDM4B,TSNAXIP1,VAMP1,SYN2,CUX2,ARHGEF12,HEY1,DAAM2,UCHL1" Drug 5682_UP Niridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,SYN3,ACTN2,NDRG2,PLA2G6,ALK,SEMA4G,SLC4A4,FGF17,SGCE,CDH2,CDH10,CHRNA4,STOML1,WHRN,VCAN,RASSF2,SPOCK2,DBN1,MAGI2,HS3ST2,ECM2,DUSP9,SGK2,TNK2,OLIG2,ZNF589,C1orf61,GAD1,GAD2,SIGLEC8,DISC1,ADAM28,LYVE1,RND1,GLI2,LILRB4,TDRKH,LPAR4,PCLO,KLF12,KCNJ4,KCNN2,VWA5A,MOBP,NF1,NPPA,ENPP2,PACSIN1,KCTD17,SLC1A6,MAPKBP1,DOCK9,DICER1,CLIP2,ZNF711,EMSY,SSPN" Drug 2812_UP Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADRA1D,NR0B1,SEMA6A,ANK1,APAF1,CADM3,CACNA1I,HAP1,CHRNB2,AKAP7,WHRN,RGS6,DAPK3,CTIF,HEPH,MYEF2,TRAPPC9,SGK2,SORBS3,HSD17B14,DMTN,STX2,ETV1,DLC1,BAIAP2,DPYSL4,GAD2,GCNT2,GNAO1,GNG4,IRF8,VWA5A,GIT1,MYH7,NDUFA5,NF1,NTRK2,PPP5C,PRKCB,MAPK8,RAB3IL1,CRTAC1,RFX2,ZFHX4,MYH14,KLHDC8A,ROM1,TCP11L1,RYR1,SEMA6D,SLC1A2,SHANK2,PDZD2,SYP,SYT5,TEX15,CABIN1,NT5M" Drug 3436_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NDRG2,SEMA6A,LTBP4,DOC2A,AMPD3,BIN1,APC,APOC1,PPFIA3,MADD,CDK13,ALDH4A1,KIF1A,CFLAR,GYG2,LDLRAD4,TAOK2,HOMER3,PICK1,CSF1,GREB1,DCAF8,LYPD1,RCAN1,CNNM1,STX2,VPS26C,SRCAP,GLYR1,TDRKH,ADAMTS13,KLF12,INPP5B,KCNJ3,IPO5,LSS,KITLG,CD200,PDE3B,PLEC,TNPO2,PRKAR1B,MAPK8,PTPRE,GSTCD,TCP11L1,ANKRD6,PHLDB1,PLCB1,TCF7,ZNF34,TK2,CDK20,TRPC1,MICAL1,SPHK2,ITM2C,PHTF2" Drug 3135_UP Alfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,ADCY6,PPFIA2,ASPH,CCDC181,KIF1A,BMP7,CDK5R1,CACNB2,HIP1R,LARGE1,TAOK2,ZFYVE9,SLC4A8,NRG2,NCOR2,ABCG1,CRYM,ARHGEF10,RIMS2,TRAPPC9,E2F5,CNNM1,SORBS3,LRRC23,F5,C1orf61,GPR153,DENND2A,ALDH1L1,GNG3,GPM6A,GRM7,C2orf72,IGSF1,KCND3,KCNQ3,MAP4,MID1,MYO6,CNOT4,OMG,NECAB2,KLK6,PLPPR1,PTPRN2,NEK11,TCP11L1,SYNDIG1,PREX2,SLC11A1,ZCCHC24,IZUMO4,ZFR2,DOCK9,SEZ6L,VIPR2,SPHK2" Drug 2634_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADD2,ADORA2A,AP2A2,GAS7,ALDH4A1,N4BP2L1,ATP6V0A1,BAIAP3,CA4,CACNB2,ARHGEF1,MAGI1,TAOK2,ABI3BP,RCHY1,PDE4DIP,EDRF1,CTIF,MFAP3L,OPTN,DENND4A,NCALD,PTK2B,FGF1,SEMA4D,GAD1,SIGLEC8,GLYR1,GRB10,ATXN2L,ICA1,INPP5B,KCNN2,VWA5A,ADAM22,MSR1,NPPA,PLCD1,PPP2R2B,SAMD9,PTHLH,RAB3A,CCDC40,RGS10,RGS12,GSTCD,PAQR6,FAM214B,PKNOX2,SLC9A5,IZUMO4,VAMP1,SMG6,SEZ6L,METTL3,WIPF1,PHTF2,AP3B2" Drug 3713_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADCY2,ADD2,BEGAIN,RASL11B,ATP1A2,N4BP2L1,BMP7,SCAPER,BAIAP3,KALRN,FOXN3,CLCN4,HOMER3,NCOR2,PDE4DIP,SPOCK2,MAGI2,SV2B,ECM2,MBNL2,EPHB1,EFCAB2,FYB1,GABRG2,SIGLEC8,SRCAP,GLRB,POLL,GPM6A,ADAMTS13,ICA1,IGFBP1,LAMA2,NF1,TNPO2,MINDY2,PRKCB,PTPRN2,C1orf54,FAM184A,ZCWPW1,RFX2,RGS4,PBRM1,RPS20,KCNIP1,DGLUCY,DZIP1,RPH3A,SLC2A5,HECW1,SPP1,KDM4C,ZMYND8,RPRM,OSBP2,LMF1,NUP214" Drug 2701_UP "estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACTN2,MTUS1,PKP4,ZBTB10,SLC16A4,TAOK2,EPS15L1,RAB33A,CNTN1,SLC4A7,CREM,DZIP3,USP6NL,DGKG,DBT,SMG7,DLG4,HIPK3,FCF1,SRPK3,EIF1,CAMSAP1,FHL1,CSPG5,GABRA2,GAD2,LILRA2,RAPGEF1,GSN,HPSE2,ITGAM,KCND3,KCNK1,MEF2C,TAGLN3,KCNK10,PENK,MINDY2,PTPN13,RAB3A,RBBP6,RGS4,PNMA8A,SYNDIG1,HSPA4L,RPH3A,SLCO1A2,CXXC4,TCF7L2,RPGRIP1L,CRTC1,AHCYL2,TPM2,SSBP2,HIRA,UBE3A,PRDM10,PHTF2" Drug 3016_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "C3orf14,ACTN2,CDC42BPA,APAF1,SYNJ1,SYNJ2,CHRNA4,FAM149A,PPP1R16B,BRINP1,TOM1,DYRK1A,E2F5,EEF1A2,MBNL2,AASS,COQ7,CDKL3,DLC1,EFCAB2,SIGLEC8,GNAS,LILRA2,GRK4,PADI2,VWA5A,MAPT,AFF1,AFDN,NINJ2,NNAT,CNOT4,NPR2,NUMA1,OLR1,ST8SIA5,PPARA,PTPRB,RAD52,RALGDS,ZDHHC14,TCP11L1,SCN2B,SEC14L1,FRMPD1,NLGN1,DZIP1,ANKRD6,WDTC1,SPART,TCF7L2,RPGRIP1L,OBSL1,THRA,CDK20,TRO,ZMYND8,JPH3" Drug 4669_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "TRMT9B,AMT,PPFIA4,CDC14B,EIF4G3,ADAM23,ABCG2,AKAP7,TCEAL2,ARHGEF10,PDE4DIP,CNTNAP2,CTNND2,BRINP1,CNIH3,RABGAP1L,ATN1,CNNM1,OPTN,ING4,CDKL3,ETV1,SORBS1,C1QL1,MSL3,GPM6B,GRM8,ITPKA,AFF1,NEK1,NF1,PAK3,STRN3,FAM120C,TMEM231,RGS10,KIRREL1,ZNF671,RPS6KA2,FOXRED2,IL17RB,ZNF821,FRMPD1,SMARCD3,SNCA,KDM4C,ARHGAP26,IQSEC2,SUPT5H,PLCB1,TBL1X,TNS1,TRPC1,WNT7A,SF1,WNK1,PRDM2,NT5M" Drug 6090_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "DPF1,RALGAPA1,SPARCL1,ALK,PLA2G4C,BAIAP3,CALB2,FOXN3,SULT4A1,CRYM,CSF1,SPOCK2,DBT,SV2A,DNAH9,EDN3,TENM1,DMTN,LRRC23,EFS,F5,FGFR1,FOXG1,FOLR2,CAMKK2,FYB1,SRCAP,GPM6A,ATF7,GSN,KCNJ5,MBP,MYT1,NPPA,PALM,PDPK1,RETREG1,EPN1,PPP5C,SAMD9,ZDHHC14,ZMAT4,RYR1,SLC9A5,SOX15,PEG10,ARHGAP26,TACR1,PSD3,TLL2,R3HDM1,PIK3R5,CHST5,WIPF1,SLC30A3,SLC17A7,KCNAB1,MVB12B" Drug 6641_DN Khellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "MRTFA,APOC1,CDC14B,CDK13,DNAH17,KIF1A,ST3GAL5,CACNA1I,CHN2,ABCG2,WHRN,NCOR2,VCAN,CNTNAP2,CTIF,MFAP3L,CNNM1,TNK2,PLEKHO1,IGSF6,ZNF549,CDKL3,CORO2B,ST3GAL6,C1orf61,TRMO,ZNF44,DISC1,POLL,GPM6B,GPR19,LPAR4,KCNJ5,LSS,MAPT,MDFI,MEIS1,AFDN,LYRM9,NF1,NOS1,NPR2,OPCML,GRAMD1C,SAMD9,MYH14,ASAP3,SHANK2,ZNF415,RAP1GAP2,TROVE2,KLHL4,TK2,TRIO,ZMYND8,WIPF1,ZNF32,NUP214" Drug 3721_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ASPHD1,KLRC4,ADORA1,MRTFA,APBB1,EPB41L5,DDO,APP,PDE8B,ATP6V0A1,NRP2,BAIAP3,TPP1,PDE4DIP,RABGAP1L,TRAPPC9,ECM2,EFNB3,RGS17,NCALD,EFS,ABCA8,BAIAP2,FYB1,GABRA5,GAP43,CPLX2,GPR19,GRK4,SPACA9,ICA1,TJAP1,KCNH2,KCNJ5,AFF1,NEUROD1,OLR1,PDE2A,PDE3B,PRKAR1B,MAPK10,ZSCAN2,ZCWPW1,KIRREL1,FNDC3A,RPH3A,PEX26,ARHGEF40,SLCO1A2,SCN3B,SOX2,INKA2,ACSBG1,TAL1,OBSL1,TRH,LAT2,NUP214" Drug 6729_UP Erythromycin [114-07-8]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "NDRG2,AP2A2,ALK,PKP4,ASCL1,SLC2A11,HAP1,USP2,SCARB1,FOXN3,CHN2,TMEM59L,VAX2,IQCK,CSF1,SRGAP3,DTNB,DUSP9,DYRK1A,HIPK3,ING4,EPHB1,APC2,DLC1,NSG1,ALDH1L1,RUNDC3A,RAPGEF1,GRIK5,GRM7,GUCY1A2,PTGDR2,ATXN2L,BACH2,HPSE2,KCNJ5,MYCN,LYRM9,PALM,PGAM2,PIK3CD,POU6F1,MAPK8,RASA3,SH3BP2,CNKSR2,NLGN1,SLC11A1,SLC15A2,PLCB1,PCDHGB6,FAM189A1,AP4E1,TRH,TRPC1,TRPC3,PARP11,NLRP3" Drug 3381_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADD2,KCNAB2,ATP1A3,CFLAR,KSR1,CDO1,CHRM4,RAB33A,AKAP6,IFFO1,CSF1,MFAP3L,SRGAP3,SGK2,ERCC2,REEP2,FGFR3,FOXG1,SIGLEC8,ADAM28,GNG3,GRB10,GRIK5,GSN,KLF12,HLF,KCNMA1,LAMA2,ADAM11,OPRL1,LRRN3,CEP41,MAPK7,VPS13C,PTAFR,RAD52,ZMAT4,PNMA8A,EMID1,SELL,ST6GAL1,KDM4B,MLC1,ABCC8,ARC,POPDC3,ROBO3,WSCD1,CABIN1,PIK3R5,TRPC3,UCHL1,LAT2,SLC30A3,SCG2,SLC17A7,PHTF2,NUP214" Drug 4658_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACHE,MRTFA,AMPH,APOC1,ARHGDIG,DNAH17,ATP1A2,ALDH7A1,NOL4,SYNJ2,CACNB4,USP2,MTMR7,CDH10,GPR37L1,ABCG1,SUSD5,RIMS2,ELN,ERBB4,ETV1,ABCA8,TUBB4A,CAMSAP1,NSG1,GABRA3,MYOZ2,GPR75,POLL,GRK4,GRM1,BACH2,HTR2A,IRF8,KCNJ3,MGAT3,NF1,P2RX7,PROX1,ZSCAN32,RGS12,TCP11L1,SCN2B,MRAS,CNKSR2,DZIP1,KANSL3,SORCS3,SPTB,ATP10B,RPGRIP1L,PCDHA5,TEX15,ZNF34,SEZ6L,UBE3A,KAT6A,CAMK1G" Drug 4218_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ACHE,PPFIA4,AQP4,PPP4R4,ASCL1,ATP1A2,AZGP1,RGS11,KSR1,BMPR1B,CA4,CCK,USP2,SLC16A4,LARGE1,DLGAP1,GPR37L1,NRXN3,FAM149A,COL9A3,GAL3ST1,CRYBB1,DYRK1A,MRNIP,EPB41,RASGRP2,GABRA5,RUNDC3A,TOX3,ADAMTS8,HTR5A,IGSF1,KCNJ5,KCNJ9,MMP16,NCAM1,LRRN3,MAPK8,PTH1R,PTPRG,RASGRF1,SCN2B,RASA3,SLC1A6,KANSL3,DOP1A,INKA2,MAPK8IP3,VAMP1,TACR1,CRB1,TLL2,TLR4,SEZ6L,NPL,PRMT8,FLRT2,XRCC4" Drug 2436_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "C3orf14,BEGAIN,ANK3,PPFIA3,PRX,CCDC181,KIF1A,ADGRB1,CACNA1I,HIP1R,COL9A3,ABI3BP,NCOR2,PDE4DIP,DAPK3,MFAP3L,ST8SIA3,SEZ6L2,SORBS3,MRNIP,ELN,EIF1,FLNC,FYB1,SIGLEC8,NEU3,POLL,TDRKH,GUCY1B1,MSI1,ADAM22,NEUROD1,PCDH9,PFKFB4,DUSP26,EPN1,SEPT4,RELN,TMEM104,PTPN13,RFX2,SYNDIG1,PKNOX2,SOX10,ZC3H13,ARC,SYT5,CAMSAP2,WWC1,TK2,TRH,TRPC3,UGT8,VAV2,VSNL1,CLIP2,SLC17A7,ADAMTSL3" Drug 2901_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "ADORA1,ANK3,APAF1,APBB2,CDC14B,PLA2G4C,ATP6V0A1,BMP7,CACNA1G,HIP1R,INA,CDH8,MAGI1,CLGN,JAM2,TAOK2,CABP1,RNF14,NOS1AP,KLHL3,DLG4,CELSR3,SORBS3,KAT8,FER,OLFM1,C1orf61,AFF2,NBEA,PRELID3A,GPR153,GJB1,GNG3,GPM6B,ATXN2L,HTR5A,ICA1,KIF5C,MSR1,SAMD14,ZNF862,MAPK8,RFX2,RGS10,MAP6D1,EMID1,RPS20,KIF16B,ZC3H13,CDK19,ATP10B,TROVE2,EXOC7,TBCEL,IQCE,CHST5,LMF1,ZFP37" Drug 3024_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "SYN3,ABHD6,AGT,BIN1,SEMA4G,PRX,SPTBN4,DDX3Y,MYOM1,CA12,CCK,INA,CDO1,CACNA2D2,CHN2,AKAP6,CREM,PDE4DIP,DLG3,DMPK,KCNMB2,PRELID3A,SIGLEC8,ALDH1L1,RUNDC3A,ZNF276,ATF7,LILRA2,GRIK5,CELF3,KLF12,KIFC3,ADAM22,OPRL1,PAH,PDE1C,PFKFB4,CCSER2,PLP1,RELN,RAD52,RASGRF1,SEC61A2,MYH14,SEMA6D,ASAP3,SLC1A2,SLN,TMCC1,SP4,IZUMO4,DNMBP,ZNF34,ICAM5,TPM2,TRPC1,VAV2,LMF1" Drug 6479_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.77E-07 4.79E-02 2.50E-05 2.84E-04 58 198 "KIDINS220,AK2,BIN1,GAS7,PLA2G4C,MARK4,ATM,ATP6V0A1,ADAM15,GYG2,BAIAP3,CACNA1A,CALB2,CCNT1,CDH10,HOMER3,BAG4,ENTPD4,GREB1,DAPK3,DRD1,DTNA,EDNRA,FCF1,MBNL2,PLXNC1,MTSS1L,KAT8,GCNT2,GLS,POLL,STON1,KCNF1,KPNA5,IPO5,NEUROD1,NFYA,P2RY1,ZSCAN32,KHDRBS2,RGS10,RNASEL,ATXN2,ZNF821,SLC1A7,PREX2,PEX26,SMTN,ELMO2,TROVE2,MAPK8IP3,ARC,CRTC1,VIPR2,VLDLR,XRCC4,SPHK2,SSPN" Drug CID000003393 flurazepam Stitch 9.95E-07 4.88E-02 2.54E-05 2.89E-04 18 35 "ABAT,CCK,SLC32A1,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GRIA1,GRIK1,ABCB1,SLC6A1,SLC30A3" Drug 2499_UP Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.99E-07 4.90E-02 2.55E-05 2.90E-04 56 189 "RALGAPA1,ACTN2,SLC12A5,AMH,DNAH17,MYOM1,RIPK1,LDLRAD4,CD86,SULT4A1,CREM,ENTPD4,CRYM,SIPA1L1,PDE4DIP,PPP1R16B,CTNND1,GPRASP1,KIAA0513,EXOG,TOM1,DNAJB6,SEZ6L2,MBNL2,EGR3,LRRC23,CDKL3,GAB1,GNG3,GPR22,KLF12,KCND1,AFDN,ZNF862,OLR1,OMG,CCSER2,PDZRN4,CEP41,RBBP6,RFX2,KCTD17,NEK11,RPS20,PAQR6,SGK1,SCG5,BCAN,SNCA,SPP1,STX1A,JMJD6,ANKRD28,CBX5,LMF1,PRDM10" Drug 2405_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.99E-07 4.90E-02 2.55E-05 2.90E-04 56 189 "CDC42BPA,APAF1,AQP4,DNAH17,CCDC181,CARS,CDO1,CHRNA4,CLCN4,TPP1,HAPLN1,PPP1R16B,CTH,DBT,MFAP3L,DTNA,EFNA3,PLXNC1,F8,FOXG1,CAP2,FYN,PCLO,RAPGEF4,GRM3,GRM8,AP4S1,ATXN2L,KLF12,ICA1,IFI16,ZNF862,NAP1L2,NPPA,OCRL,RETREG1,PPARA,PRKCZ,MAPK7,RGS3,RPS6KA2,RTN1,ASIC4,ZFP2,SEC14L1,CNKSR2,EPN2,FAM214B,WDTC1,TSPYL2,PDLIM2,KCTD2,TPM3,FLRT2,MAP3K12,SENP7" Drug CID000001884 7-chlorokynurenic acid Stitch 1.01E-06 4.94E-02 2.57E-05 2.93E-04 21 45 "GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,PDYN,SALL1,JMJD6,TAC1" Drug CID000003598 hexachlorophene Stitch 1.02E-06 5.01E-02 2.61E-05 2.97E-04 33 90 "PLA2G6,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CANX,CDH8,CLTC,MCHR1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MOBP,SCG3,OPRL1,OLA1,CCDC88A,SSTR1,SSTR2,ANKS1B" Drug ctd:D010269 Paraquat CTD 1.03E-06 5.02E-02 2.61E-05 2.97E-04 329 1647 "SERPINA3,SYN3,ASIC1,ACHE,ADAR,ADCY5,ADCY6,ADORA1,ADORA2A,ADRA1D,AGT,TXNDC16,ALAD,BBOX1,SYT13,AMPH,BIN1,ANK1,APAF1,APBB1,APP,CDC14B,RGS20,ASCL1,ASPA,DYNLL1,TMEM108,ATM,ATP1A1,ATP1A2,ATP2A2,ATP2B2,ATP6V0A1,RIPK1,TTC9B,BACH1,ADGRB1,BCHE,BCL2L2,BID,CDK5R1,GPC2,CACNA1E,CALM1,NGB,CAMK2A,CCKBR,AIFM1,CD86,CD38,DGKI,CDO1,NOG,ADGRG1,CBARP,CHRNB2,SLC22A6,NRXN3,NRXN2,CLU,NGEF,FADS2,ABCG2,NIPBL,CABP1,COX4I1,BAG4,SLC32A1,CSF1R,FEZ1,CTNND1,CTNND2,CX3CR1,NOS1AP,HDAC4,DGKB,DAPK1,DBI,SIRPA,PLEKHM1,BLOC1S6,ALKBH8,SACS,ARNT2,DMD,NR1D2,DNM2,DNAJB6,DYRK1A,FARSB,ABCC9,EDN1,EDNRA,EEF1A2,FCF1,HEYL,EBI3,EGFR,EIF4G2,IRAK4,TENM1,ELN,USPL1,ENO2,MFSD10,LRRC17,EPS8,ERBB2,ERBB4,EZH1,TUBA1B,FECH,FGF1,FGFR3,SCARA3,PCYOX1,FOXM1,FOXO3,SEMA4D,DPYSL4,SORBS1,SARAF,OGA,FYN,GAB1,GABBR1,GABRA4,GABRB1,GAD1,GAD2,GAP43,ATP8A2,GART,CPLX1,GCK,SESN1,GFAP,GFRA1,GFRA2,GHR,PPARGC1A,GJB1,TCERG1,RAB30,GLS,GLUL,OS9,KCNMB4,GNAO1,GNAS,DIPK1C,GPER1,GRIA2,GRIK3,GRIN1,CACFD1,GRIN2C,NR3C1,GRM2,GSTT2,GUCY1A1,HBA1,HMGB1,HMGCL,HNRNPK,HSPA1L,HSP90AA1,HTR2A,IDH3A,IGF1,IGFBP1,SLC6A17,ITGA7,ITGAM,KCNA1,KCNA2,KCNA4,KCNJ5,KCNMA1,CREG2,KIFC3,KIT,STMN1,LIFR,SMAD1,MAG,MAP2,MAPT,LYPLAL1,MBD1,MBNL1,MDM4,LRP1B,MEF2C,MIA2,MMP17,ADAM22,MSRA,MT3,SCG3,NACA,FXYD6,NCF2,NDP,NEFM,NEFH,NEUROD1,NEUROD2,NF1,NFE2L2,NOS1,NRDC,NTRK2,P2RX7,P2RY1,GPR137C,PAX6,PDE1B,PDGFRA,PDYN,PENK,PFKFB3,PFKFB4,PFKP,ABCB1,PIK3R1,RETREG1,PLCB2,SMOX,PLP1,PLTP,FAT3,PPARA,PPP3CA,PPP5C,PRKAR1B,PRKCZ,MAPK3,MAPK4,MAPK8,MAPK9,MAPK10,NDUFS7,SPDL1,PTN,TMEM231,RAD17,GTDC1,RGS4,RPS6KA2,LRRK2,SOX8,RXRA,STX1B,TRAPPC13,S100B,ATXN1,ATXN2,SCN2B,SGK1,SCG5,SH3GL2,EPN2,SLC6A9,SLC6A11,SLC8A1,CCDC88A,SLC11A1,SLC15A2,SMARCC2,CDK5RAP2,SNCA,PALLD,SOX1,ZHX3,SPP1,SPTAN1,KIF1B,SRPK2,SST,STX1A,MLC1,SYN1,SYN2,SYP,SYT1,SYT5,SEMA4A,PJA1,MGRN1,ACSL6,TCF7,TEX15,ATP13A2,TF,SIRT1,THBS4,THRA,TJP1,TLR4,NR2E1,HEY2,DAAM2,PRRT1,TNR,TP53BP2,RUNDC3B,TRPC3,TSC2,TTPA,TUBB1,UBC,UCHL1,VGF,SLC47A2,ATP6V0E2,LYPD6,TMEM198,WNK1,TUBA1A,SLC17A7,NELFE,GOPC,RTN4,RSPRY1,NLRP3,AAAS,AP3B2,ST8SIA2" Drug ctd:D000661 Amphetamine CTD 1.04E-06 5.11E-02 2.65E-05 3.02E-04 47 149 "ASIC2,ASIC1,ACHE,ADORA2A,ADRA1D,ALAD,ANXA7,RGS9,CACNA1D,CALB2,CALM1,CCKBR,CHRM1,CREM,CSNK1E,DBN1,DRD1,ENO2,F3,GABRA1,GABRG2,GAD1,GFAP,GRIA2,GRIN1,GRM1,GRM5,IGFBP1,KCNA1,MAOB,CD200,NPY,PDYN,PENK,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK8,PTN,RGS3,RGS4,SGK1,SLC6A9,ARC,TAC1,SCG2" Drug CID000002482 butamben Stitch 1.05E-06 5.16E-02 2.68E-05 3.05E-04 11 15 "CACNA1I,CACNA1A,CACNA1B,CACNA1E,ACOT8,KCNA1,KCNC1,KCND1,KCND2,KCND3,L1CAM" Drug 5398_UP Azacyclonol [115-46-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "ASIC1,KIAA1324,PLA2G6,LTBP4,MRTFA,AMPH,SEMA7A,APAF1,APBA2,CDC14B,PLA2G4C,CBFA2T2,ARHGAP33,CRLF1,NRXN1,PICK1,CRMP1,EDNRA,EDNRB,FER,CAMKK2,PRELID3A,HBS1L,USP19,GLS,GNAL,CNTRL,GRB10,GRIN1,GRM8,GSTM5,RASSF8,ATXN2L,SCRG1,ICA1,KCND3,LMO2,MAOB,TAGLN3,MYO7A,NCAM1,NDP,NOVA2,NPR2,NRGN,C1orf54,TTLL7,ASAP3,KDM4D,TNIK,SPTB,WSCD1,PIK3R5,UBE2H,WIPF1,SYNC,ITM2C" Drug 2742_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "MTUS1,CDC42BPA,PKP4,APAF1,APBB2,PPP4R4,SYNJ1,CD86,QKI,CSF1,RUBCN,ZNF337,DGKG,KIAA0753,FCF1,EFNA3,PLXNC1,ING4,NCALD,RRAGB,ZNF589,CAMSAP1,FHL1,CAP2,IQCG,ZMYND11,INPP5K,LILRA2,GPR22,IL6ST,LIG4,VWA5A,MAP4,MDM4,MEF2C,PIK3R1,CCSER2,PILRA,CEP97,ZFHX4,CARF,TMCC1,TSPYL2,ATP11A,TCF7L2,PSD3,CRTC1,AHCYL2,ZNF34,TPM3,TRPS1,SSBP2,FLRT2,NSD2,SYNC,ZNF225,PCBP4" Drug 6833_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "ASIC1,AP2A2,AGT,BIN1,MARK4,SLC4A4,SYNJ1,CFAP410,USP2,GPR37L1,RCBTB2,CHRNB2,LY86,CNTFR,CPS1,NCOR2,RIPOR2,CTIF,RUSC2,MAGI2,SMG7,CDON,SHANK1,ST8SIA3,PLXNC1,ELAVL3,VPS13B,SPEG,FGF13,ZNF44,PCLO,SPACA9,VSIG4,MID1,ADAM22,MSR1,ZNF862,POU6F1,MAPK8,RIPOR1,CCDC40,RAD52,ZFHX4,MYH14,ASIC4,CPEB3,LIMS2,PDZD2,TSNAXIP1,ARC,POPDC3,SPX,R3HDM1,TPM3,AMACR,XRCC4,NT5M" Drug 6897_UP NS-398; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "ABHD6,ALCAM,OGT,ANK3,APOC1,CDK13,STX16,ALDH7A1,KIF1A,ADAM15,CFLAR,SCAPER,BTRC,CCNT1,CDH18,SLC4A7,C2CD2,CREM,DNAJC6,LYPD1,DMPK,EDNRB,FEM1B,IRAK4,BAIAP2,CINP,COPS8,GNG3,KCNJ3,KHK,MMP17,NEK1,NFYA,NUMA1,PC,ZSCAN32,RAB3IL1,GTDC1,RGS12,TTLL7,SLC22A4,PDZRN3,CDK19,LHPP,CLASP2,NXT2,ST5,PCDHA6,ZNF34,SLC44A1,TRPC1,RPRM,VGF,ZNF24,WNK1,MAP3K12,PRDM2" Drug 7538_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "NME5,PKP4,APBB2,APC,RGS20,CDK13,ASPH,ADAM15,SPAG9,CBFA2T2,PLEKHB1,CLCN4,TBC1D5,MATR3,GIT2,DYNC1I1,FCF1,YAF2,EGFR,ETV1,RRAGB,ZNF589,FHL1,FLT1,GNAS,GPD2,EML4,BACH2,INPP5B,LIG4,MBNL1,MYO6,NF1,NUMA1,SETD4,OCRL,PPP5C,BCAS3,CNTLN,RAD51D,ATG16L1,GSTCD,PEG10,TAB2,SS18,NXT2,SEMA4A,SATB2,TRIM2,KAT6B,TRPC1,LAT2,ZNF45,ZFAND5,SEMA3B,MPPE1,KAT6A" Drug 6835_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "ASIC1,AMH,AMPD3,AMPH,AMT,MARK4,N4BP2L1,ADAM23,CFAP410,CA4,CACNA1A,ENTPD2,FADS2,CNTN1,NRG2,CDC42BPB,CRMP1,ABCG1,PDE4DIP,MAML1,RUSC2,DMPK,SGK2,OPTN,EFNB3,CELSR3,SORBS3,ELN,MTSS1L,ERCC2,BAIAP2,SORBS1,FYB1,SEPT9,SRCAP,AHDC1,GRM1,IL6R,ADAM22,ZNF862,TTLL7,SUGCT,S100B,SCN2B,SH3BP2,FAM214B,WDTC1,TSPYL2,MAPK8IP3,SYT5,TBL1X,SZT2,PSD3,FLRT2,SF1,NT5M,KAT6A" Drug 7379_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.08E-06 5.31E-02 2.75E-05 3.13E-04 57 194 "NME5,ALK,KCNAB2,SHROOM2,ATM,NRP2,CFLAR,CACNA2D1,PLAA,STOML1,AKAP12,CNIH3,MFAP3L,RABGAP1L,DLG3,USH1C,CNNM1,TNK2,BSCL2,PLEKHO1,ANKFY1,CGREF1,ATP8A2,USP19,BACH2,SHISAL1,IL12A,KCNN1,MDFI,MT1M,NDP,CLDN11,PALM,PDE4D,PMP2,LRRN3,PRPH,APTX,PTPRH,RGS12,PBRM1,FBXW7,IL17RB,ABLIM3,SMARCC2,SNCA,SOX2,TNIK,SAMSN1,PHLDB1,GPR161,CABIN1,VIPR2,NAV2,WIPF2,EPM2A,NUP214" Drug 2457_UP Hexetidine [141-94-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.11E-06 5.42E-02 2.80E-05 3.19E-04 55 185 "ACTN2,BIN1,DNAH17,CCDC181,BCL2L2,CFLAR,USP2,CD86,CD38,CHRNA4,ZFYVE9,PICK1,CREM,CSF1,SIPA1L1,VCAN,DOCK4,GPRASP1,DCT,FCF1,MBNL2,ATP8A1,BAIAP2,PRKAG2,FHL1,AFF2,POLL,GNG4,GRM8,IFI16,JAK2,KCNMA1,MX1,NOVA2,OLR1,P2RY1,TREM2,MAPK8,BCAS3,WDR25,PLPPR1,RAD52,KHDRBS2,RGS12,SEC61A2,RIMS1,ATP10B,CAMSAP2,TEX15,AP4E1,TK2,ZMYND8,VGF,SLC17A7,SENP7" Drug 4365_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.11E-06 5.42E-02 2.80E-05 3.19E-04 55 185 "C1QTNF3,ALAD,APBB2,PDXK,CAMK2G,SRSF11,FOXN3,LHX2,FADS2,RAB26,SDC3,RIMS3,DPYSL2,ING4,PLEKHO1,ERCC2,ARMCX1,TESK2,TMEM164,SEMA4D,SYT17,SESN1,STON1,RNFT2,MUM1,IGSF1,ITPKB,MAPKAP1,MBOAT7,RAB3IL1,RALGDS,RET,RGS12,SBF1,FAM214B,FAM168A,VAMP1,VPS13A,PLCB1,ASTN2,SEMA4A,TBL1X,KIAA0930,TNS2,TMEM121,ZMAT3,SLC44A1,HEY2,BEX4,RUNDC3B,ZMYND8,ZNF32,REEP1,LRP8,MPPE1" Drug 2403_UP Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.11E-06 5.43E-02 2.81E-05 3.19E-04 51 167 "ABAT,ADD3,GAS7,ARRB2,DNAH17,CFLAR,ST3GAL5,CD86,CD38,RCBTB2,CHN2,TPP1,CREM,SIPA1L1,PPP1R16B,DOCK4,FAM13A,LPAR6,PIPOX,PRKAG2,TRAF3IP2,STON1,VWA5A,NCF2,OLR1,PDE4B,PDE4D,SMOX,MINDY2,SEC14L1,SGK1,DOCK10,SLA,FAM214B,ARHGEF40,ZSWIM8,SPTAN1,CDK19,SS18,STX1A,ARHGEF9,PLCB1,DNMBP,CAMSAP2,PDLIM2,KIAA1107,TBL1X,FLRT2,CLIP2,ZBTB38,MAP3K12" Drug CID005462126 AC1NUW3V Stitch 1.17E-06 5.71E-02 2.90E-05 3.29E-04 16 29 "GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 3702_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASIC1,CCDC181,ATP2A2,CADM3,BMP7,CACNA1I,LDLRAD4,CD86,DCLK1,MAGI1,CHN2,CHRNB2,STOML1,HAPLN1,AATK,CSF1R,PDE4DIP,CYBB,DTNA,MTSS1L,ZNF391,FGFR1,C1orf61,AGAP2,CSDC2,GRK4,SPACA9,GRIN1,SOX21,NXPH3,PTGDR2,ATXN2L,HLF,INPP5B,ITGA7,MDFI,LYRM9,NTRK3,NUMA1,PLXNB1,PDZRN4,VPS13C,PTCH1,RGS12,ZFP2,STUM,NTNG1,SLA,SLC15A2,CXXC4,PLCB1,ARC,MCF2L,OBSL1,TNS1,TPM1,CADM1,EPM2A" Drug CID000023982 gadolinium Stitch 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASIC2,ASIC1,ST3GAL5,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,AIFM1,CRLF1,CACNA2D2,GDA,CTH,SACS,CASP8AP2,CACNG7,OPTN,ADGRV1,F8,CACNG2,TUBA1B,GAD1,GALC,B4GALNT1,NEU3,GFAP,GHR,GRIA1,GRIA2,GRIA4,GRM1,GRM3,TNFAIP8L3,IGFBP1,KCNK2,MBP,CD200,MTR,NEFH,NF1,NPPA,KCNK10,PKD1,RYR1,RYR3,ASIC4,MRAS,ST8SIA1,TNFRSF1B,SMUG1,TRPC1,TRPC3,SIGLEC10" Drug 2287_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ADGRF5,MRTFA,AMPD3,BIN1,CDC42BPA,MARK4,CFLAR,SYNJ2,MTMR3,BAIAP3,SLC16A4,CHRNB2,HAPLN1,MFAP3L,SRGAP3,NTM,EXOG,HSD17B14,LRRC17,STX2,ZNF589,OLFM1,MALT1,GLS,GRB10,NR3C1,GRM8,HLF,AGFG1,KPNA5,MAOB,MAP2,MAP4,MEF2C,ADAM22,NCAM1,NNAT,NPY,C19orf57,MAPK7,PROX1,MYH14,ZNF821,SH3BP2,SLC2A5,CCDC88A,COA1,FAIM2,SOX15,PRRC2C,WSCD1,TCF4,CRTC1,PCDHA5,TEX15,TRPM2,FLRT2,EVI5" Drug 5066_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "NR0B1,AMH,AMPH,APAF1,ATP2B3,ADAM23,GYG2,BAIAP3,IL33,CDH10,CHGA,ZFYVE9,NRXN1,PDE4DIP,RIMS2,DTNA,EDN1,NCALD,EFS,FGFR1,C1orf61,DCTN2,ATP8A2,ALDH1L1,CSDC2,LYVE1,RUNDC3A,LPAR4,HPSE2,KCNF1,KCNJ5,LAMA2,ADAM11,NF1,SLCO1C1,NOVA2,PALM,GDPD2,CCDC40,RAD52,ZCWPW1,RGS12,RIT2,SCN2B,IL17RB,SLA,SLC1A7,PKNOX2,NACAD,KLHL4,ZMYND8,VSNL1,ZNF74,STMN4,SEMA3B,MVB12B,CAMK1G,NUP214" Drug 2237_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ARID1A,NDRG2,MRTFA,AMPD3,APBA2,PLA2G4C,ATM,CFLAR,BMP7,HAP1,ARHGEF2,ARHGAP33,RCBTB2,ZFYVE9,FADS2,AKAP7,COL9A2,SLC4A7,SEC14L5,RIMS3,EIF4G2,ING4,COQ7,ANKMY1,ZNF589,BAIAP2,FHL1,FAM49B,TMEM8B,SRCAP,MALT1,COPS8,GNAS,GNG4,ICA1,IPO5,MBD1,MIA2,MMP16,NEK1,SERPINE2,PPP5C,GON4L,TCP11L1,PREX2,PEX26,DOK5,SPTAN1,IQSEC2,STX1A,PSD3,NSD1,TMOD1,TRIO,HIRA,SPHK2,WNK1,SMIM8" Drug 5992_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "LTBP4,MRTFA,DOC2A,CDC42BPA,APBB2,CCDC181,CADM3,SCAPER,CACNA1D,PDE4DIP,DCAF4,CX3CR1,TBC1D5,DBN1,DUSP9,EDNRA,HIPK3,EGFR,ING4,C3orf18,SPEG,CDHR1,NRN1,DLC1,FOXG1,CAMKK2,FYB1,SIGLEC8,ALDH1L1,HPGDS,GPD2,GRIN1,GRM8,ATXN2L,DHX35,HTR5A,VWA5A,MDFI,NNAT,OPCML,MAPK8,NKAIN1,TRIM68,ZFHX4,RASA3,ITSN1,ASAP3,KIF13A,TSNAXIP1,THSD1,ACSBG1,WSCD1,PARD3,TNS1,CHST5,LAT2,KCNK12,JPH3" Drug 7465_UP Spaglumic acid [4910-46-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "SEMA6A,BIN1,AMT,APC,DNAH17,BMP7,KYAT1,NEURL1,CDC42,MAGI1,CHRNB2,SDC3,SPOCK2,DNM1,DTNA,CELSR3,SORBS3,EPB41L1,PRELID3A,SYT17,RUNDC3A,GRM1,RNFT2,AFF1,MPP2,NELL2,NF1,PCDHGC3,SERPINE2,PRKAR1B,ZSCAN2,ZFHX4,ROM1,TCP11L1,PAQR6,FRMPD1,SLC1A7,PREX2,PPP4R3A,SLC11A1,CXXC4,WDTC1,TSNAXIP1,ZBTB43,CEP68,SEMA4A,TBL1X,TRIM2,PSD3,TIAM1,KCTD2,VAV2,SLC13A3,REEP1,SEMA3B,EPM2A,MARCH8,NUP214" Drug 4132_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "AGT,LTBP4,SYT13,APBB2,AQP4,ATP1A2,NRP2,CBFA2T2,ZFYVE9,CRY2,AATK,CSF1R,SPOCK2,ARMCX2,NTM,DYRK1A,EFNB3,SPEG,DCTN2,NSG1,FYB1,GPR75,GPR22,GRIK1,ATXN2L,KLF12,BACH2,JAK2,KCNJ5,SMAD1,ADAM22,NCF2,SLCO1C1,OPCML,PDE1C,GPR85,CEP41,PRKAR1B,PTAFR,PTCH1,RAB3IL1,CCDC40,TRIM68,DOCK10,SLC1A3,SLC14A1,SLCO1A2,KIF21B,ZC3H13,COLGALT2,SSTR2,INKA2,PHLDB1,TAL1,KIAA1107,TCF7,PIK3R5,SLC30A3" Drug 6072_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "NDRG2,ADD2,GAS7,GYG2,BAIAP3,HAP1,RUNX1T1,FOXN3,GREB1,RASSF2,CNIH3,ELN,RASGRP2,KCNMB2,PTK2B,DLC1,ZNF589,FHL1,FOXG1,TBR1,GFRA2,RUNDC3A,GRIK3,GRM1,GRM7,GSTM5,HAS2,CD200,MYO7A,PLCD1,MINDY2,PPP5C,MAPK8,PTHLH,C1orf54,TRIM68,RFX2,CARF,RYR1,SCG5,SLA,RPH3A,SLC9A5,MYT1L,CAND2,UNC5B,PHLDB1,ACSBG1,VAMP1,SEMA4A,SMG6,TCF4,TK2,PDIA2,CLIP2,ETNPPL,KCNK12,SYNC" Drug 1489_UP Antipyrine [60-80-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "PLA2G6,BIN1,AMT,CDC42BPA,APC,BCAS1,MARK4,ATP2A2,BACH1,MPDZ,CFLAR,SYNJ2,B4GALT6,QKI,SULT4A1,CREM,FAM169A,DZIP3,ZNF804A,LYPD1,DMPK,EDNRA,LRRC23,LRRC17,F3,DLC1,FER,FHL1,TPK1,GAB1,INPP1,IPO5,MBD1,MOBP,NEUROD1,NUMA1,OPCML,KCNK10,PDE4A,RETREG1,C1orf54,EMID1,SH3BGR,SH3BP2,ASAP3,SLC2A5,MAPKBP1,RBM34,KDM4C,VAMP1,ARHGEF12,CRTC1,CHST8,TMOD1,R3HDM1,SF1,REEP1,SSPN" Drug 2297_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "TKTL1,ADCY2,ADGRF5,CDC14B,CFLAR,LDLRAD4,CAMK2B,INA,SLC22A6,FADS2,AKAP6,TENM4,ARHGEF10,IPCEF1,TRAPPC9,DSCAM,DYRK1A,ST8SIA3,MBNL2,ELAVL3,ERCC2,FYB1,GAB1,TMEM8B,LYVE1,GLS,TJAP1,ITIH2,KCND3,MAOB,MAPT,ADAM22,NEFM,NTRK2,PDE4A,PPARA,RELN,RASGRF1,RGS4,TTLL7,SLC14A1,FAIM2,SPP1,SPTB,RBM26,INKA2,SYT5,POPDC3,DOCK9,PSD3,GPR161,PIK3R5,TRPC1,TRPC3,CLIP2,LAT2,MVB12B,PLSCR4" Drug 5544_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASIC2,ADRA1D,NLGN4X,ANK2,CDC14B,CDK10,DNAH17,ATP6V0A1,HIP1R,CD86,CLCN4,SIPA1L1,VCAN,CNTNAP2,DZIP3,EDRF1,SEC14L5,SPOCK2,SLC12A6,SGK2,FCF1,C3orf18,SPEG,F5,GPR153,B3GAT1,GNG3,GPD1,GPR22,RASSF8,KCNJ4,MAOB,MBD1,MDFI,MSR1,NF1,ABCB1,PPARA,ELOVL2,MARCH1,KHDRBS2,ZDHHC14,TCP11L1,SH3GL3,SYBU,SMTN,KIF13A,INKA2,SYN2,TBL1X,WSCD1,PSD3,ZKSCAN5,VIPR2,XRCC4,ZIC3,TRIM9,PRDM2" Drug 6410_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "GAS7,PPP4R4,ALDH4A1,CACNA1I,CDK5R2,BTRC,ARHGEF1,CRY2,TBC1D5,ARMCX2,B3GAT3,RUSC2,CHRDL1,DLG3,DMPK,SORBS3,FGFR1,DLL3,TRAF3IP2,MSL3,PRRC2B,GPM6B,TDRKH,HSF2,ICA1,MEF2C,MIA2,MOBP,NPR2,PDGFRA,PLCD1,PLXNB1,PRKAR1B,PTCH1,TMEM231,RAB3IL1,ZCWPW1,MYH14,NEK11,PAQR6,RXRA,SBF1,SCN8A,BTBD7,IFT122,CEP68,SYN2,COBL,ASTN2,DMXL2,SZT2,TNS2,AHCYL2,TK2,ZNF74,HPS4,KCNAB1,SENP7" Drug 4635_DN Androsterone [53-41-8]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "TRMT9B,AMH,APC,PDE8B,ATP1A3,CADM3,ADGRB2,BAIAP3,GPR37L1,CHI3L2,PLEKHB1,LHX2,RAB26,AKAP7,CABP1,CSF1R,ARHGEF4,SGSM2,RABGAP1L,DTNB,HEYL,AASS,ING4,LRRC23,MTSS1L,NRN1,FGFR3,AFF2,CINP,FYN,ZNF44,SIGLEC8,GLYR1,GPM6B,CACFD1,SOX21,ICA1,KCNF1,MARK3,MYT1,NEUROD1,CNOT4,PALM,RGS10,KLHDC8A,FOXRED2,SCN8A,ZNF821,SH3BP2,FRMPD1,SLC1A7,AHCYL2,CHST8,THRA,TIAM1,UGT8,NT5M,STMN4" Drug 5071_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "N4BP2L1,NOL4,BAIAP3,NEURL1,CACNA2D2,CHRNA4,RIMS2,DRD1,ELN,DENND4A,CEND1,F5,REEP2,KIAA1109,OLFM1,FGFR1,AGAP2,GABRA5,SIGLEC8,GPR75,GNG4,GPM6B,GRIK1,KCNN1,NEUROD1,NOVA2,NUMA1,PCSK2,PDE4A,PDE4D,PIK3R1,PPARA,MINDY2,PPP1R1A,PPP2R2B,LRRN3,GRAMD1C,PLPPR1,PID1,KHDRBS2,CRTAC1,RGS10,RGS12,KCTD17,SLA,SLC1A7,PKNOX2,FAIM2,HECW1,RBM26,PLCB1,ARC,TRIM2,CHST8,THRA,CABIN1,SEZ6L,TRPC3" Drug 4065_UP Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "MTUS1,NME5,ALAD,MRTFA,CDK10,ZSCAN18,ADAM15,ADGRB2,BCHE,SCAPER,CACNA2D1,KALRN,CLCN4,HAPLN1,NCOR2,CSF1,CSF1R,PHF14,C2CD2L,RABGAP1L,EDIL3,ZNF391,ETV1,CEND1,PDLIM5,PRELID3A,DISC1,NEU3,GPER1,CACFD1,HSD17B1,IL6R,MSR1,PBX1,PDGFRA,PLCD1,CNNM2,ELOVL2,PTN,RGS4,TMEM206,KCNIP1,ASAP3,NTNG1,FBXO11,SLC14A1,KDM4B,IZUMO4,CDK19,RBM26,NPAS3,SS18,PHLDB1,SYT5,DAAM2,TNS1,ZNF225,KCNAB1" Drug 6658_UP Luteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASPHD1,AK2,PKP4,APBB1,KCNAB2,EPB41L5,ATP2B2,ADGRB2,CFLAR,CFAP410,HAP1,SLC16A4,SCARB1,CHRNB2,FHL5,ENTPD4,CRY2,SPOCK2,ATN1,DSCAM,DTNA,DYRK1A,IGSF6,CDKL3,ETV1,FGF1,GABRA4,ADAM28,CSDC2,CACFD1,NCKAP1L,KCNB1,KCND2,KCNJ5,PAK3,PDE3B,NECAB2,CEP41,PTAFR,TMEM206,FBXW7,RYR1,ZFP2,SCG5,NTNG1,SLA,SHANK2,ZNF334,SLC15A2,RIMS1,SCN3B,ZBTB43,ATP10B,PHLDB1,TF,UCHL1,PRDM2,KCNAB1" Drug 3744_DN Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "MTUS1,APC,APOC1,CDK13,ALDH4A1,STX16,SCAPER,BTRC,CACNB2,PLEKHB1,CLCN4,FAM189A2,CNTN1,CHD1L,CREB5,NCOR2,VCAN,ARHGAP24,CDON,ATN1,DTNA,DUSP9,HIPK3,SIDT2,FAM13A,PLXNC1,EML1,EN2,FGF1,ANKFY1,PDLIM5,PRELID3A,KCNMB4,GRIK5,SCIN,MAN2A2,NPR2,PC,PIK3CD,STRN3,MINDY2,CEP41,PTCH1,RAD52,SUSD4,GSTCD,MCMBP,FBXO11,PREX2,SLC9A5,TSNAXIP1,DOK5,CHST8,GPR161,TPM2,XRCC4,SF1,WNK1" Drug 6040_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "GRAMD1B,BEGAIN,ANK1,DDO,CFAP410,CAMK2B,SLC24A2,STOML1,WHRN,PLCH2,DOCK4,ARHGAP24,DCT,SPOCK3,EFS,CDHR1,ZNF589,KIAA1109,OLFM1,FGFR1,BAIAP2,DCTN2,CAMKK2,ERAP1,GRIA1,SYNPO,IL12A,KCNN1,CD200,NPPA,KCNK10,ENPP2,DUSP26,POU3F4,PRKCB,MAPK7,MAPK8,ELOVL2,PTPRB,ZMAT4,CARF,RPS6KA2,ASIC4,SELL,FRMPD1,RPH3A,SLC1A7,FAM214B,PKNOX2,WDTC1,UNC5B,JMJD6,CRTC1,TLR4,HEY2,TPM2,MICAL1,LAT2" Drug 5784_DN Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "C1QTNF3,AMT,CDC42BPA,APC,APP,ARNTL,ALDH4A1,CFLAR,CDK5R1,RCBTB2,NRXN3,BAG4,CPS1,CREB5,HAPLN1,CSF1,DZIP3,TOX,AASS,MRNIP,DENND4A,ETV1,ATP8A1,ZNF589,SORBS1,SRCAP,GPR19,RNFT2,GUCY1B1,KIF2A,KIF5C,MATN3,MOBP,GIT1,SNTG1,PBX1,PRKAR1B,SAMD9,ELOVL2,PTPRH,RAD52,RALGDS,FAT4,RGS7,RXRA,SH3BP2,ASAP3,AMBRA1,KDM4C,ZNF423,DDN,SYT1,SYNE1,DNAH7,BEX4,CABIN1,VIPR2,ZNF74" Drug 7396_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "DPF1,AP2A2,ADGRF5,ALAD,AMT,SLC4A4,NRP2,CA4,KALRN,CDH10,TAOK2,CRMP1,NCOR2,CTNND2,RIMS2,RIPOR2,EXOG,DTNA,HIPK3,PLEKHO1,ZNF391,ZNF549,FCGRT,TESK2,FGF13,GAD2,GFER,GPR75,GPD2,LPAR4,GRK4,SCRG1,HNMT,IL12A,KCNJ5,MGAT3,WDR25,RIPOR1,RAB3A,TTLL7,NEK11,EMID1,SBF1,IL17RB,FUZ,SLC11A1,SLC20A2,SNCA,SYN2,THRA,TK2,RBFOX2,ZKSCAN5,SCG2,KCNAB1,PARP11,EPM2A,UBE3B" Drug 3777_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "LTBP4,PDE8B,SLC2A11,GYG2,CACNA1I,CACNA1D,KALRN,RUNX1T1,RGN,ZFYVE9,KIAA1549L,CLCN4,PDE4DIP,TOX,DBT,ATN1,DSCAM,DTNA,DTNB,HEYL,ELAVL3,CEND1,FGFR3,SEMA4D,FLT1,ERAP1,RUNDC3A,RND1,GNG4,RAPGEF1,GRIK2,GRM7,KLF12,HPSE2,KCNJ5,MEF2C,MMP17,CD200,SLCO1C1,NPY,NPTX1,PBX1,LRRN3,MAPK10,RGS10,SELL,ZNF821,SUPT20H,DOCK10,BCAN,SLC14A1,SLC15A2,SNCA,PDZRN3,SCN3B,MCF2L,TPM3,TUBB1" Drug 2545_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "SYN3,AP2A2,AMH,APBA2,ASTN1,AZGP1,KSR1,CACNA1G,SLC16A4,LARGE1,CRLF1,CHN1,ZFYVE9,CLCN4,NRG2,CREM,DGKG,HS3ST2,TRAPPC9,ATN1,DSCAM,ARMCX1,CORO2B,FHL1,AGAP2,PDLIM5,DLL3,FYB1,GABRA2,NEU3,GPD2,GRM8,PTGDR2,KLF12,TJAP1,ITGAM,KCND3,KCNJ5,MAP4,MX1,NEFM,NEK1,NEUROD1,OXTR,PHKG1,PMP2,RGS12,SEMA6D,SEC14L1,ZNF821,SLC11A1,ZSWIM8,MCF2L,RIMBP2,TRIO,OSBP2,BEST1,SSPN" Drug 3575_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ACTN2,LTBP4,BIN1,KCNAB2,APC,EPB41L5,ARRB2,DDX3Y,ALDH4A1,ATP2B3,SYNJ2,CAMK2A,USP2,ATRNL1,GREB1,DCC,PARD6A,EDNRA,SIDT2,EFNA3,EFNB3,LRRC23,PIPOX,F5,KIAA1109,TBR1,TRAF3IP2,GAD1,ERAP1,INPP5K,GCNT2,CACFD1,IL6ST,SMAD1,GIT1,ADAM22,NEUROD1,NF1,PALM,PDGFRA,MINDY2,PPP5C,CNNM2,C1orf54,ASIC4,FNDC3A,FAM214B,SLC9A5,CXXC4,WDTC1,TSNAXIP1,RBM26,TROVE2,SYN2,RPGRIP1L,PSD3,CHST5,NT5M" Drug 4295_UP Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "SEMA7A,PKP4,CADM3,BMP7,MTMR3,CACNA1D,SLC24A2,RCHY1,FEZ1,JAKMIP2,DTNB,EDNRA,NCALD,REEP2,FOXG1,AGAP2,FYB1,GAD2,ERAP1,ATP8A2,ALDH1L1,RND1,IL6R,LMO2,MYT1,NPTX1,NPTX2,NTRK3,OMG,OPRL1,PCSK2,PFKFB4,PIK3CD,PPARA,CEP41,PRKAR1B,MAPK8,PRPH,PTPRN2,CCDC40,EMID1,CPEB3,BCAN,DZIP1,RIMS1,RBM34,SPP1,ZC3H13,NCDN,ARC,ADGRL3,SMG6,TEX15,TIAM1,TIMP4,TMOD1,STMN4,EPM2A" Drug 2578_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "PKP4,APAF1,CDK13,ASPH,MYRF,CACNB4,SLC16A4,CDH2,VAX2,NRG2,CRY2,SLITRK5,USP6NL,DBT,KIAA0753,TMCC2,E2F5,EPB41L1,EFS,F5,GALC,ERAP1,ALDH1L1,GPR162,GSN,PADI2,TJAP1,LSS,MGAT3,NFYA,NUMA1,OMG,OPCML,CLDN11,PDE4D,POLG,LRRN3,PRKCZ,BCAS3,ZFHX4,EMID1,RXRA,ASAP3,FAM214B,PKNOX2,SLCO1A2,FAIM2,TMCC1,RAP1GAP2,ARHGEF9,DNMBP,PSD3,THRA,TMOD1,RBFOX2,ZMYND8,FLRT1,ZBTB38" Drug 6491_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "RALGAPA1,ADORA2A,ATP6V0A1,ADAM23,KSR1,GYG2,CFAP410,CACNA2D1,CDH2,CLGN,STOML1,HOMER3,ARMC8,CSF1,CHD5,PDE4DIP,MAML1,SPOCK2,HP1BP3,DTNA,EFNA3,MBNL2,ELAVL2,APC2,RRAGB,F5,SCARA3,DCTN2,PRELID3A,OGA,GCNT2,RUNDC3A,GSTM5,SOX21,KLF12,KCND2,MID1,MYO7A,NEUROD1,PLCD1,SAMD9,CCDC40,MYH14,TCP11L1,SYNDIG1,WLS,SH3BP2,SH3GL2,SLC8A2,UNC5B,PHLDB1,SMG6,WSCD1,CRTC1,SLC44A1,PIK3R5,SLC30A3,DNALI1" Drug 1511_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "SLC12A5,ALCAM,MRTFA,CDC42BPA,GAS7,APLP1,APP,PLA2G4C,CACNA1I,LDLRAD4,CALB1,CALB2,SOCS6,TAOK2,CNR1,RCHY1,CHD5,DCAF4,HDAC4,DGKG,MFAP3L,LYPD1,USPL1,EN2,RCAN2,GAD2,SRCAP,ADAMTS13,GRM7,GSN,MATK,MOBP,ZNF862,PLCB2,FAM120C,RAD52,SEC61A2,EMID1,ASIC4,ITSN1,SHANK2,SLN,CXXC4,SORCS3,SNCA,PDZD2,ARHGAP26,SAMSN1,SSTR2,TACC1,SZT2,DICER1,ZKSCAN5,FAM155A,WIPF1,LAT2,REEP1,MPPE1" Drug 2329_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ADD2,NME5,BEGAIN,BIN1,APC,PPFIA3,SEMA4G,CDK13,NUMB,CADM3,ADAM23,GYG2,BTRC,CACNA1A,CACNA2D1,FOXN3,TAOK2,AKAP7,NOS1AP,GPRASP1,RASSF2,SRGAP3,DYRK1A,EDNRA,ELN,NRN1,AGAP2,GAD2,GLS,POLL,GNAL,GRM8,TJAP1,KCND3,KCNJ5,KCNMA1,ADAM22,NNAT,NPTX1,NTRK2,SERPINE2,PLCD1,PRKCB,C1orf54,ZDHHC14,KLHDC8A,PAQR6,BCAN,SLC11A1,SP4,SPART,LMO3,ARC,POPDC3,WSCD1,TEX15,RIMBP2,TRPM2" Drug 4389_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASIC1,DDO,ATP1A2,AZGP1,BACH1,KSR1,GYG2,CNOT8,CLTB,ARHGEF10,VCAN,SPOCK2,CDON,EDN3,FAM13A,MBNL2,TNK2,ELN,CORO2B,DLC1,OLFM1,FGFR1,AGAP2,SEMA4D,SORBS1,B3GAT1,GABRG2,GAD1,GAD2,GCNT2,GPM6A,GRM1,GUCY1A2,MGAT3,AFDN,MOBP,MX1,NPY,PALM,PDPK1,PLXNB1,TNPO2,RORB,SLC1A2,SLC1A7,SHANK2,KIF13A,SPP1,SYT11,PLCB1,SYT5,TNS1,UGT8,OSBP2,WIPF1,LAT2,NT5M,NUP214" Drug 1541_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "RALGAPA1,ASIC1,AK2,APBB2,APOC1,PPP4R4,STX16,RGS9,SCAPER,CACNA1I,BAIAP3,CALB1,CDH2,CLGN,TAOK2,CSF1R,ZNF804A,CNIH3,ATN1,DTNA,EFNB3,EIF4G2,STX2,FHL1,FOXG1,FLNC,TXNL4A,TDRKH,SPACA9,GRIN1,KLF12,HLF,ICA1,KCNH2,KCNJ5,MAPT,MID1,NF1,PFKFB2,CAMKV,POU3F4,PPP2R2B,PRPH,PTN,CEP97,SCN8A,SYBU,KDM4D,SHANK2,SLCO1A2,KDM4C,ERC1,SAMSN1,KAZN,PRDM2,GDPD5,KAT6A,TIGD6" Drug 4741_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "NDRG2,MRTFA,DOC2A,APLP1,APP,ARHGDIG,PLA2G4C,CDK5R1,SYNJ2,SCAPER,CA4,SPAG9,B4GALT6,FAM189A2,QKI,WHRN,ENTPD4,DAPK3,EFNB3,DMTN,NCALD,BAIAP2,AFF2,GAD1,ERAP1,INPP5K,INPP1,KCNJ3,MIA2,MMP16,NF1,NPTX1,PDE4A,RETREG1,NLE1,PRPH,SAMD9,NKAIN1,MAP6D1,SH3BP2,ASAP3,CHD9,SYBU,EPN2,SMARCD3,EMC1,UHRF1BP1L,KDM4C,CLSTN2,PLCB1,ROBO3,TNS1,RUNDC3B,ZKSCAN5,HIRA,RPRM,FAM155A,EMSY" Drug 5783_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "SYN3,NDRG2,FAM135A,MARK4,CCDC181,BMP7,ST3GAL5,LDLRAD4,BTRC,CACNB2,MAP7,USP2,ZFYVE9,EDIL3,EDN1,EDN3,COQ7,KCNMB2,HPCAL4,GAD2,NEU3,ADAM28,POLL,PRUNE2,SPACA9,SHISAL1,KCND3,KCNF1,KCNH2,KCNN2,LAMA2,LMO2,MBP,TM6SF1,MEF2C,AFF1,ADAM22,TAGLN3,CTNNA3,OMG,MAPK3,PTN,PTPRD,GAL3ST4,SYNDIG1,FOXRED2,STUM,SLC11A1,SLCO1A2,HECW1,SPTB,ACSBG1,TEX15,TPM1,CDK20,ZMYND8,PDIA2,ZIC3" Drug 3228_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ALK,APBB2,MARK4,ATP1A3,N4BP2L1,NRP2,SYNJ2,CFAP410,CA4,RUNX1T1,CBFA2T2,CHGB,ARHGAP22,COL9A3,BAG4,GREB1,EDRF1,CYBB,DTNB,SEMA3D,NCALD,FAM198B,ZNF589,FGFR1,GAB1,HBS1L,ATF7,GRM1,HLF,HNMT,IL6ST,KCNJ5,SMAD1,GIT1,NPTX1,PCBP3,NTRK2,CDK18,PDE3B,ENPP2,MBOAT7,PPP2R2B,CNNM2,RGS12,MYH14,CARF,SLC8A1,DOK5,SPTB,ATP10B,TBCEL,CRTC1,AP4E1,TGFBR3,TK2,FLRT2,DNALI1,PLSCR4" Drug 2921_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ABHD6,ARID1A,ADORA3,AMPD3,BIN1,CDC42BPA,RASL11B,ATP2B2,LDLRAD4,INA,CBFA2T2,CDH10,CLCN4,SIPA1L1,RIMS2,CNIH3,KLHL3,DLG3,EFNA3,ELAVL3,EPB41,DLC1,NBEA,PRELID3A,GLYR1,GLRB,GRIK1,IL1RAPL1,SLC2A6,NXPH3,ATXN2L,ITIH2,KCNN1,MGAT3,MPP2,ZNF862,CNOT4,NPR2,NRCAM,P2RY1,DUSP26,NLE1,PLCD1,PPP2R2B,MAPK8,MORC4,FERMT1,BCAN,SLC1A3,SLC11A1,WDTC1,CRTC1,TEX15,CHST8,TRIO,TRPC1,FAM155A,LMF1" Drug 6327_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ARID1A,MTUS1,CDC42BPA,ANK1,APBB2,PPFIA3,PPP4R4,MADD,CFLAR,BTRC,CACNA1D,MAP7,SCARB1,CACNA2D2,CHRNB2,WHRN,AATK,FEZ1,ARHGAP24,RIMS3,DYRK1A,E2F5,SIDT2,EFNA3,CELSR3,PLXNC1,ETV1,PIPOX,ST3GAL6,SCARA3,AFF2,SORBS1,FYB1,ERAP1,RASSF8,HTR2A,KCNMA1,MDFI,ZNF862,NDP,NF1,NPPA,NUMA1,MINDY2,MAPK7,PTHLH,GAL3ST4,SEMA6D,ST6GAL1,SLC1A7,KIAA1107,TBL1X,ARHGEF12,KCNK12,SPHK2,REEP1,SEMA3B,KCNAB1" Drug 6132_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ABAT,C1QTNF3,BEGAIN,AMPH,CDC42BPA,SPTBN4,BTRC,CA4,CACNG1,THSD7A,CBFA2T2,FAM149A,PHYHIP,DGKG,SPOCK2,CNIH3,KLHL3,SV2B,SV2A,DYRK1A,EEF1A2,OPTN,ERBB4,ETV1,FGFR1,SORBS1,GAD2,ZMYND11,GAP43,SIGLEC8,RUNDC3A,GNAO1,GRM1,GRM7,KIF3A,KCND3,KPNA5,CD200,NTRK3,P2RY1,KCNK10,PILRA,PLPPR1,PTPRB,WLS,LIMS2,SHANK2,SLC14A1,PDZD2,NPAS3,TROVE2,TACR1,WWC1,TBCEL,KCNE5,SH3GLB2,KCNAB1,SSPN" Drug 5517_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ABCD2,APBA2,CDC14B,ATP1A3,ATP2A2,ATP6V0A1,CACNA1I,CACNB4,CACNG1,USP2,MTMR7,NEURL1,CDH10,TAOK2,CNN3,WHRN,ARHGEF10,EDRF1,MAML1,SPOCK2,BRINP1,TRAPPC9,LRRC17,BAIAP2,DLL3,GNAS,GNG3,GPER1,GRB10,KLF12,INPP1,KCNB1,KCND3,IPO5,ZNF862,NF1,OGG1,PDE3B,GPR85,PLXNB1,LRRN3,GDPD2,TTLL7,PRR5L,RPS6KA2,SBF1,CNKSR2,ANKRD6,SMTN,ELMO2,KIF13A,DOK5,ZC3H13,PLCB1,WSCD1,ZEB1,TRPC1,SCG2" Drug 5269_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ARID1A,ADORA1,LTBP4,SYT13,FAM131A,CDK13,ASPH,ATP2A2,MTMR3,CACNA1I,CALB2,CAMK2B,RUNX1T1,CHRNB2,TAOK2,CREB5,CSF1,SDC3,SEC14L5,SPOCK2,ATN1,EGR3,ATP8A1,DLL3,ATP8A2,GCNT2,GRIK5,GRM1,HLF,JAK2,KCNMA1,KIT,MID1,NEFM,NPY,TMOD2,SERPINI1,CEP41,MAPK7,GDPD2,ZNF493,NTNG1,PKNOX2,FAIM2,TNIK,IZUMO4,PHLDB1,VAMP1,SYT5,DMXL2,ZEB1,DOCK9,SLC35G2,CHST8,TMOD1,PIK3R5,VIPR2,MVB12B" Drug 3532_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ASIC2,ADORA3,SEMA6A,ALCAM,ABCD2,APBA2,FAM131A,ALDH4A1,ATP2A2,ADAM23,SULT4A1,LY86,CRMP1,CSF1R,SDC3,RASSF2,GIT2,DMPK,FRY,TNK2,ERCC2,ATP8A1,GALC,DISC1,SEPT9,RND1,GPR22,KLF12,ELOVL5,TJAP1,IGSF1,ITGA7,MMP16,MOBP,TAGLN3,NF1,NTRK3,PCSK2,PDE4D,PTAFR,PTHLH,PTN,FAM120C,ZNF493,RFX3,TCP11L1,RPS6KA2,RYR1,SYBU,SLN,TROVE2,RPGRIP1L,SYNE1,DOCK9,PDIA2,ITM2C,ST7,NUP214" Drug 2322_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "PLA2G6,OGT,CDK13,SLC2A11,CA4,CAMK2B,B4GALT6,PLAA,DNAJB5,HOMER3,AKAP7,PPP6R2,HP1BP3,LYPD1,PARD6A,SORBS3,DMTN,F3,KAT8,KIAA1109,FHL1,SEPT9,INPP5K,POLL,NR3C1,GRM7,ATXN2L,INPP5B,KCNN1,KCNN2,VWA5A,MPP2,NFYA,SLC25A23,PLXNB1,STRN3,MBOAT7,PRODH,PTCH1,FAM184A,RGS10,ROM1,TCP11L1,SBF1,SH3BP2,ELMO2,BTBD7,SPTAN1,PHLDB1,AP4E1,SLC44A1,CABIN1,CADM1,MICAL1,WIPF1,PRDM2,HPS4,KAT6A" Drug 6586_DN prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "ACTN1,BRAP,PPFIA1,CDC14B,ADGRB2,CFLAR,KSR1,SYNJ2,CFAP410,KALRN,CDC27,B4GALT6,CNTN1,NRG2,PLCH2,TOX,ARMCX2,KAT8,BAIAP2,POMT1,GLYR1,MSL3,GNG4,GPER1,CNTRL,CACFD1,TAGLN3,PBX1,CDK18,POU6F1,PRPH,TMEM104,PTX3,SH3TC2,ZCWPW1,RGS7,TTLL7,MYH14,CCDC25,ROM1,PEX26,CCDC88A,SHANK2,ZNF415,KDM4B,DOP1A,FNBP1,PBLD,THSD1,TCF7L2,TRIM2,SZT2,TNS1,SSBP2,CADM1,RPRM,TFIP11,NAV2" Drug 7318_DN Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-06 5.73E-02 2.90E-05 3.29E-04 58 199 "MTUS1,CDC42BPA,ANK3,APBB2,PPFIA3,CDK10,EIF4G3,MTMR9,RIPK1,CFLAR,CDK5R1,ARHGEF7,IL33,CHN2,AKAP7,CSNK1E,VCAN,DZIP3,USP6NL,FBXL5,DLG3,FCF1,MBNL2,ZNF589,CAMSAP1,TRMO,SEPT9,COPS8,MSL3,ARHGAP19,HNMT,SHISAL1,IL11RA,ITPKB,TAGLN3,MX1,NEK1,NUMA1,ODF2,SMOX,SAMD9,GON4L,RAB3IL1,RGS4,FBXW7,SHANK2,SLC22A4,LIMCH1,ARHGAP26,SRPK2,IQCE,ZNF34,SSBP2,NDRG4,SH3GLB2,MAP3K12,PCBP4,FZD3" Drug CID000008035 "2,5-hexanedione" Stitch 1.20E-06 5.86E-02 2.96E-05 3.37E-04 24 56 "ACHE,BCHE,APPL1,TUBD1,TUBB3,TUBB4A,CINP,TUBA8,GFAP,TUBA1C,TUBB2B,KCNA4,KCNH1,MAP2,KITLG,NEFM,NEFH,CLSTN2,ADHFE1,TUBB2A,TUBB1,TUBA1A,NUP214,GAN" Drug 4500_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-06 5.89E-02 2.97E-05 3.38E-04 56 190 "ADRB2,KIDINS220,PLA2G6,SYT13,AMPD3,APAF1,BCAS1,CDK13,ATP6V0A1,MTMR3,CDC42,TAOK2,NRXN3,CLCN4,SULT4A1,HOMER3,CABP1,AKAP5,CSF1,MICAL2,CHD5,PDE4DIP,SPOCK2,DBT,AMOTL2,FLT1,PDLIM5,FYB1,GBX2,GFER,RND1,PTGDR2,KCND3,PDE1C,PDE3B,PFKFB2,SERPINI1,PIK3CD,C19orf57,CEP41,PTPRD,PTX3,RASGRF1,RGS7,MYH14,ASIC4,FRMPD1,KANSL3,FAIM2,SOX2,ZHX3,SPP1,NACAD,DOCK9,VGF,ZNF225" Drug 4362_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-06 5.89E-02 2.97E-05 3.38E-04 56 190 "ARID1A,BIN1,AMT,KCNAB2,APP,PLA2G4C,HAP1,CLGN,ADGRG1,SOCS6,LHX2,TPP1,NMT2,FADS2,SH2B1,CNTNAP2,DAPK3,GIT2,DTNA,EFNA3,EFNB3,RRAGB,FOXG1,PDLIM5,TPK1,INPP5K,PCDH17,GLYR1,GRIK5,IL6ST,INPP1,KITLG,MMP16,SSH1,PIK3R1,LRP12,MED1,NKAIN1,ATG16L1,TCP11L1,MAP6D1,SEC14L1,RASA3,PPP1R9A,ASAP3,FUZ,PEX26,EXOC7,PDLIM2,TCF7L2,PSD3,HEY2,TMOD1,REEP1,SNX27,RNF146" Drug 4507_DN Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-06 5.89E-02 2.97E-05 3.38E-04 56 190 "MTUS1,PLA2G6,AMT,ANK3,APBB2,APC,ASPH,SLC4A4,SCARB1,ARHGAP33,CHM,DNAJB5,PDE4DIP,CNTNAP2,FCF1,EGFR,EIF5,STX2,ETV1,KIAA1109,FGFR1,FAM49B,GCNT2,SPIN1,POLL,FERMT2,MAP4K5,AGFG1,IL6ST,MAP4,PIK3R1,MED1,MAPK8,ATG16L1,SLC25A36,GSTCD,KIRREL1,SEC14L1,ZFP30,PPP4R3A,BTBD7,SPTB,RAP1GAP2,PRRC2C,TBL1X,EHBP1,PSD3,AHCYL2,TEX15,DICER1,BHLHB9,XRCC4,TFIP11,WNK1,KAT6A,FXR1" Drug ctd:D005038 Ethylnitrosourea CTD 1.26E-06 6.18E-02 3.11E-05 3.54E-04 78 294 "AP2A1,ALK,APC,EPB41L5,BLM,DST,CACNA1A,CCKBR,INA,LARGE1,CACNA2D2,CHGB,LHX2,PLAA,QKI,HECTD1,DMD,MED12,DRD1,RCAN1,EDN3,EDNRB,EGFR,EMX2,STX2,ERBB2,ADGRV1,FDFT1,FECH,FOXF2,POMT1,NCKAP1,GCK,FREM1,GJB1,GNAS,GRIK1,GRM8,KIF3A,ITPKB,JAK1,KCNJ11,KCNQ2,KIT,LAMA2,MBD1,AFF1,MYO5A,MYO6,MYO7A,MYT1,NFIX,NFYA,NOS1,NTRK2,OPRL1,PAX6,PCSK5,NLGN3,PKD1,PMP22,PPARA,RELN,RAB3A,RASGRF1,RPRD1A,SCN8A,SGK1,SLC6A8,SPP1,SYP,TEK,DICER1,SIRT1,ZFPM2,ZIC2,PCDH15,IFT88" Drug CID000001779 "5,7-dichlorokynurenic acid" Stitch 1.27E-06 6.23E-02 3.14E-05 3.57E-04 22 49 "ADORA2A,SLC25A18,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,PTPA,TACR1,TPM3,SLC17A7" Drug CID000073212 lead compounds Stitch 1.29E-06 6.32E-02 3.18E-05 3.61E-04 47 150 "ADCY2,ADCY5,ADCY6,ADCY8,ALAD,ATP1A2,ATP2A2,CACNA1I,CACNA1G,C5,CACNA1A,CALM1,NGB,PLCXD3,DTNA,EDNRA,ERCC2,FECH,AFF2,CRCP,GRIA1,PLCD4,GRIN2C,GRIN2D,HBA1,HNRNPK,ITGAV,KCNK2,MYL3,NOVA2,SLC11A2,KCNK10,PLCB2,PLCD1,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,PTX3,RYR1,RYR3,COPZ1,SLC11A1,PLCB1,CA10,FXR1" Drug 6379_UP PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ARID1A,ADRA1D,C1QTNF3,MRTFA,APAF1,APBB2,APP,ARRB1,DNAH17,ALDH7A1,ATP6V0A1,ADGRB2,CACNA2D1,CBS,NRXN3,STOML1,FAM149A,IFFO1,NCOR2,CYBB,HS3ST2,TRAPPC9,ATN1,DTNB,CELSR3,EGFR,PIPOX,DLC1,KIAA1109,CAMSAP1,C1orf61,EFCAB2,OGA,GABRB3,LILRA2,ADAMTS8,MATK,MMP16,MOBP,MYH6,NTRK2,PDGFRA,RGS4,TCP11L1,BCAN,SLC9A5,ZHX3,COLGALT2,SZT2,DICER1,GPR161,TNS1,TPM2,SLC13A3,ZNF74,MAP3K12,MVB12B" Drug 983_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ALCAM,PPFIA3,CDK13,SCAPER,SLC16A4,ARHGEF2,CLGN,GPR37L1,COL9A3,CSNK1E,DCAF8,JAKMIP2,G3BP2,DTNA,EGR3,VPS26C,KIAA1109,FHL1,PDLIM5,DLL3,GLYR1,BTN2A1,HLF,ICA1,IL6ST,INPP5B,LSS,MGAT3,AFDN,MMP16,MPP2,ADAM22,CNOT4,PHKG1,PLTP,MINDY2,PPP5C,MAPK7,PEX5,RAB3IL1,CEP97,GSTCD,EMID1,SLC22A4,LIMCH1,SNCA,KIF13A,TSPYL2,RGL1,STX1A,ATP11A,SEMA4A,TRIM2,OSBP2,VGF,VLDLR,PHTF2" Drug 4686_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "NDRG2,KIDINS220,NME5,AMPD3,CDC42BPA,APC,CASK,CDK13,PDE8B,CFAP410,ARHGEF1,FADS2,CREM,CSF1,FEZ1,PDE4DIP,CTH,EDRF1,RASSF2,FBXL5,PARD6A,SGSM2,EFNB3,PLXNC1,RASGRP2,FGF12,GLYR1,NR3C1,GRM3,KLF12,KCNJ3,TM6SF1,MYT1,NF1,VPS13C,PTHLH,RAD51D,ROBO1,KCNIP1,FRMPD1,SLC22A4,LIMCH1,FNBP1,SP2,ZC3H13,SPART,TROVE2,NEK4,MLC1,PCDHA6,AP4E1,ZKSCAN5,UBE3A,WIPF1,LAT2,SLC30A3,NT5M" Drug 4070_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "APP,CADM3,ADAM15,ADGRB3,NRP2,BMP7,CACNA2D1,CAMK2B,RUNX1T1,CHGA,STOML1,CSF1R,MICAL2,PHF14,ARHGEF4,C2CD2L,SPOCK3,RASGRP2,APC2,PIPOX,FABP7,FGF12,HPCAL4,PDLIM5,PRELID3A,CSPG5,GABRB3,NEU3,RUNDC3A,GNAO1,GRM7,MAG,TAGLN3,NF1,NTRK2,OMG,SMOX,PPP2R2B,PTCH1,PTPRN2,ACSS3,CCDC40,SUSD4,RGS12,RNASEL,TMEM206,SCN2B,ASAP3,FAM214B,SLC14A1,SLC20A2,SNCA,KIF13A,TEX15,WNK1,MVB12B,AP3B2" Drug 5797_DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ADD2,ADRA1D,APP,MTMR9,MPDZ,C5,NRG2,CPS1,HAPLN1,CRY2,CSF1R,EDRF1,C2CD2L,LYPD1,DYNC1I1,TOM1,LPAR6,DENND4A,RRAGB,FGF1,FGFR1,CINP,PDLIM5,TRAF3IP2,PCDH17,GLRB,KCNMB4,MUM1,ICA1,IL6ST,MAPT,ZNF862,SNTG1,PBX1,POU3F2,MAPK7,PTHLH,RAD52,RGS4,RGS7,PREX2,SIRT2,CCDC88A,SMARCD3,DDN,JMJD6,SYN2,ATP11A,MCF2L,SYNE1,ARHGEF12,TMEM121,TK2,ZKSCAN5,UGT8,SCG2,GAN" Drug 7393_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ADCY6,AMPD3,CDK10,SLC4A4,EIF4G3,CACNA2D1,KALRN,CACNA2D2,CHI3L2,SLC4A8,CRMP1,PARD6A,DPH1,ATN1,DYRK1A,CNNM1,ING4,PLEKHO1,COQ7,EFS,ETV1,FGFR1,DENND2A,ZNF276,GLYR1,PRUNE2,GPER1,DHX35,SHISAL1,IL11RA,DIPK1A,KCND3,LMO2,KITLG,MYH7,PDE4B,SPATA6,PPP5C,FAM120C,RAD52,ZDHHC14,EMID1,TRAPPC13,SUPT20H,FUZ,PPP4R3A,ARHGEF40,SOX2,ZSWIM8,BEX1,SPTAN1,TRIM2,DOCK9,AP4E1,XRCC4,PRDM2,UBE3B" Drug 3860_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "KIDINS220,NME5,SEMA7A,KCNAB2,RGS20,CDK13,ASPH,SLC4A4,STX16,CAMK2B,NEURL1,ADGRG1,CHM,NMT2,STOML1,FADS2,PICK1,AKAP5,CPS1,NCOR2,FAM169A,DCAF4,DAPK3,CTIF,DYRK1A,FGFR1,CAMSAP1,C1orf61,FLNC,CAMKK2,FUT9,NEU3,SRCAP,C1QL1,RUNDC3A,SPIN1,GPER1,PCLO,GSN,IL6ST,ITIH2,KCND3,KPNA5,LSS,MEF2C,KITLG,MMP16,PDE1C,LRRN3,PTHLH,SELL,SLC1A2,SLN,RBM34,POPDC3,SPHK2,SYNC" Drug 4174_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "DPF1,ADD2,AK2,ALK,BEGAIN,APBA2,APC,EPB41L5,GAS7,CHRD,ATP2B2,CFLAR,BAIAP3,ADGRG1,CHN2,WHRN,CSF1,ARHGEF10,VCAN,CNTNAP2,HDAC9,ELMO1,HP1BP3,EDN1,PLXNC1,TNK2,C3orf18,STX2,EFS,ANKMY1,KIAA1109,FGFR3,AGAP2,FAM49B,SRCAP,GUCY1A2,KLF12,SYNPO,KCND3,KCNMA1,SLCO1C1,OPCML,PLCL1,MAPK7,PTCH1,RGS12,TTLL7,GSTCD,EMID1,PKNOX2,RBM26,LMO3,ATP10B,KIAA1107,DMXL2,DOCK9,NT5M" Drug 4309_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ACHE,TKTL1,ALK,BEGAIN,PPFIA4,APAF1,CDC14B,CDK10,ATP1A2,CA12,CAMK2B,CBS,ADGRG1,CHI3L2,DNAJB5,CABP1,COL9A3,CSNK1E,PDE4DIP,RIPOR2,TRAPPC9,ATN1,DSCAM,SNX29,TENM1,ETV1,ATP8A1,FGF1,CAMSAP1,ZNF44,SEPT9,GLYR1,ADAMTS13,HRH3,KLF12,KCNMA1,MYCN,CNOT4,NTRK2,NUCB1,PDE4A,PFKFB4,EPN1,TNPO2,MAPK7,ZSCAN2,RGS4,FOXRED2,SH3BP2,CNKSR2,SLC8A2,SLC11A1,WDTC1,IQSEC2,DDN,KAZN,TPM1" Drug 5229_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "AGT,NME5,KIAA1324,ALCAM,ALK,SEMA7A,APBB2,MARK4,ASPH,CFLAR,HAP1,CDC42,ARHGAP33,CLGN,SOCS6,SLC4A7,NCOR2,VCAN,CTH,CDON,DRD1,HIPK3,MBNL2,C3orf18,DMTN,KIAA1109,FGFR1,AGAP2,TPK1,GAD2,ZMYND11,GAP43,RUNDC3A,GLYR1,POLL,CNTRL,GRIK5,KPNA5,ZNF862,OGG1,PDE4B,PLCD1,TCP11L1,SH3BP2,SMTN,FAIM2,ZCCHC24,ATP10B,NXT2,WSCD1,R3HDM1,CDK20,TRIO,TRPM2,UCHL1,SLC17A7,EPM2A" Drug 3669_DN Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ACTN1,ADRB2,ALK,APC,CDC14B,CDK13,SLC4A4,SCAPER,SEPT7,CACNA2D2,IQCK,VCAN,CNTNAP2,HDAC9,TOX,CTIF,RABGAP1L,CDON,SGK2,FEM1B,SIDT2,CDKL3,FGF1,PNMA2,OGA,GBX2,GPR17,CACFD1,RNFT2,GUCY1B1,TJAP1,KCNB1,EPN1,FSD1,PTN,GAL3ST4,ROM1,SCN8A,AMBRA1,ELMO2,ZNF415,THSD1,SS18,ASTN2,EXOC7,PDLIM2,PSD3,AHCYL2,CDK20,TPM2,PLPPR2,VAV2,LAT2,WNT7A,TFIP11,KAT6A,RNF146" Drug 2924_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ADCY2,ADORA1,PLA2G6,AMPD3,SEMA4G,ALDH4A1,CACNA1D,HIP1R,CBFA2T2,CHN2,JAM2,SULT4A1,AKAP6,FAM169A,CTNND2,SPOCK2,DNAJC6,KLHL3,ABCC9,EDIL3,EFNB3,ZIC4,C1orf61,AFF2,GAD2,GNG4,GPM6B,ADAMTS13,GSN,LAMA2,MAPT,ADAM22,P2RY1,PDE4A,EPN1,PPP2R2B,GTDC1,TCP11L1,KCNIP1,ASIC4,CNKSR2,SLC1A3,SLC1A7,SLC6A11,SLCO1A2,WDTC1,SP4,IZUMO4,ZC3H13,SPTB,TACR1,KAZN,SZT2,ATP13A2,CDK20,ZBTB16,SLC17A7" Drug 2907_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ADD2,ADORA1,ADRA1D,MTUS1,ANK3,APAF1,DNAH17,PTCH2,CAMK2G,LARGE1,CHRNA4,CLCN4,PICK1,ABCG1,EDRF1,RIMS3,DAPK1,MFAP3L,KLHL3,SV2A,DYRK1A,SORBS3,SPEG,FCGRT,NBEA,SRCAP,RUNDC3A,GRIK5,CELF3,KLF12,HPSE2,SCAMP5,MMP16,ADAM22,MYO6,NINJ2,NPPA,EPN1,SLC25A23,MTRF1L,PURG,EPB41L4B,LRRC49,PTPRN2,KLHL11,MYH14,TCP11L1,GALNT10,ITSN1,BCAN,SHANK2,IQSEC2,ATP10B,NCDN,TMOD1,TNS1,RPRM" Drug 3038_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "SYN3,ADGRF5,BIN1,LGR5,BMP7,CRLF1,CHRNA4,CLCN4,RAB26,CNTN1,PDE4DIP,RIMS2,SNPH,BRINP1,MAGI2,ATN1,USH1C,EPHB1,ARMCX1,KAT8,FGF13,FOXG1,DLL3,GAD2,B4GALNT1,GLRB,GNAL,GPR19,GRM3,PTGDR2,HRH3,HNMT,SCIN,KCND3,MBP,ADAM11,ADAM22,NRCAM,PLXNB1,EPB41L4B,LRRC49,MARCH1,MYH14,MAP6D1,SEMA6D,ASIC4,IL17RB,SHANK2,SPTB,ROBO3,TBCEL,PHF24,PCDHA3,TRO,RPRM,FLRT1,PMEPA1" Drug 7469_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ADCY6,ADORA1,SEMA6A,ALCAM,MRTFA,BIN1,ARHGDIG,PDE8B,SLC4A4,SYNJ2,SCAPER,BAIAP3,CAMK2G,CD86,CRLF1,FOXN3,NECTIN3,CREM,NCOR2,CSF1,CTH,ARMCX2,CDON,DUSP9,RGS17,VPS26C,FLNC,ERAP1,INPP5K,USP19,TXNL4A,RAB30,GLS,KLF12,IL6R,MIA2,MMP16,MYT1,PALM,PPP2R2B,PRKAR1B,GON4L,PTN,RAP1GAP,CCDC25,TCP11L1,RPS6KA2,EMID1,MAPK12,WDTC1,ZCCHC24,ZHX3,ROBO3,XRCC4,ZNF32,TFIP11,UBE3B" Drug 5269_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "NDRG2,SLC12A5,SEMA4G,PDXK,PLA2G4C,DNAH17,ALDH4A1,ATM,KIF1A,CFLAR,SYNJ2,CA4,FOXN3,VAX2,PDE4DIP,EXOG,MBNL2,ING4,COQ7,FGF13,GNG3,TDRKH,GPER1,CACFD1,RNFT2,SLC2A6,ATXN2L,ELOVL5,IL6ST,KCNJ3,KIF5A,MMP16,MPP2,GIT1,ADAM22,ZNF862,NDUFA5,PPP2R2B,PRKAR1B,RAB3IL1,ZDHHC14,RGS12,CARF,ZNF821,PREX2,SLC6A8,ZNF430,CXXC4,ZHX3,PHLDB1,PSD3,AP4E1,TK2,VLDLR,KCNK12,SYNC,EVI5" Drug 3757_UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "ACTN2,NDRG2,APBB2,DNAH17,ATP2B2,BMP7,GYG2,CAMK2B,CHI3L2,AKAP6,CABP1,NCOR2,LRIG1,ERC2,ARNT2,DRD1,ATN1,MRNIP,CDHR1,PDLIM5,GNAL,GRM7,PADI2,SCRG1,HTR2A,IGF1,KCNB1,KCND2,KCND3,LAMA2,MARK1,MATK,MMP17,ADAM22,SLCO1C1,NPTX2,PCSK1,PLP1,DCHS2,RNASEL,RAVER2,S100B,STUM,RASA3,CPEB3,PREX2,LIMCH1,KIF13A,VAMP1,MCF2L,TCF7,R3HDM1,TRO,TMPRSS5,TUBB1,UBE3A,ZNF24" Drug 2283_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-06 6.37E-02 3.18E-05 3.61E-04 57 195 "RALGAPA1,ADRA1D,APBB2,GAS7,ARRB2,ALDH7A1,CADM3,CFLAR,BTRC,LHX2,NMT2,QKI,ABCG1,GREB1,RIMS2,RCAN1,CELSR3,EGFR,VPS26C,ANKFY1,GCNT2,SRCAP,GPD2,GRIK5,ITPKB,LSS,MAP4,MDM4,KITLG,MSI1,ADAM22,ZNF862,NF1,PDE3B,PLCD1,STRN3,POLG,MINDY2,MAPK8,PRODH,RGS10,KLHDC8A,GSTCD,SH3BP2,PREX2,PEX26,PPP4R3A,WDTC1,TSNAXIP1,POGZ,SS18,ELOVL4,PLCB1,PCDHA6,TMPO,CDK20,ZKSCAN5" Drug 4652_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.35E-06 6.62E-02 3.30E-05 3.75E-04 53 177 "GRAMD1B,APC,SHROOM2,NCOA1,BCL7A,SCAPER,MAP7,QKI,NRG2,SLITRK5,ARHGAP32,TBC1D5,RBM12,VPS13B,LRRC23,GPHN,SYNCRIP,ANKFY1,DENND2A,NR3C1,HAS2,ARHGAP19,KLF12,SYNPO,JAK2,NDP,NFYA,PPP5C,SYTL2,PTHLH,PTK2,FAM120C,RGS10,TCP11L1,ATXN1,SFPQ,ZNF365,EPN2,SON,TNIK,TAB2,SS18,SYT1,MTCL1,DNMBP,FBXW11,TCF7L2,WDR7,PSD3,NSD1,TK2,PARD3,NSD2" Drug CID000003562 halothane Stitch 1.36E-06 6.65E-02 3.32E-05 3.77E-04 82 314 "ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,AK2,APOC2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CH25H,CACNA2D2,CHRM1,CHRNA4,CHRNB2,PLCXD3,EDN1,CACNG7,F3,CACNG3,CACNG2,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CYP46A1,GLRB,GPT2,GRIA1,PLCD4,GRIK1,GRM5,GSTM5,GSTT2,HAPLN2,HTR2A,KCNB1,KCNH2,KCNJ3,KCNK2,KCNK3,KCNMA1,MAG,BCO1,MYH7,NOS1,KCNK10,GNG2,PIK3C2A,PKD1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,PTK2,PYGM,RYR1,RYR3,DDN,PLCB1,TPCN2,TF,KCNK12" Drug CID000000285 AOAA Stitch 1.36E-06 6.69E-02 3.33E-05 3.79E-04 33 91 "ABAT,PDXK,CBS,KYAT1,BOC,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GGT7,GGT5,GLS,GLUL,GPT2,CNDP1,GRIK1,GRIN2C,GRIN2D,PENK,APTX,GSTCD,MLST8,ZEB1,AZIN2,TRH,ETNPPL" Drug CID000022083 IPSP Stitch 1.37E-06 6.71E-02 3.34E-05 3.80E-04 32 87 "SLC12A5,ADORA1,CACNA1B,CACNA1E,SPAG9,SLC25A18,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,INPP5K,GLRB,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNA1,GPSM2,TNPO2,RIT2,SLC6A1,RUSC1" Drug 6162_UP Mesalamine [89-57-6]; Up 200; 26.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "AP2A2,ALK,CDC42BPA,ANK3,APOC1,AZGP1,FGF17,SYNJ2,CFAP410,CACNA1D,RUNX1T1,CHRNB2,JAM2,NDST3,CNTN1,RIMS2,BRINP1,DSCAM,EDIL3,EDNRA,EFNA3,MBNL2,SORBS3,ING4,DMTN,C1orf61,FOLR2,DENND2A,RUNDC3A,HPGDS,PCSK1N,GNAO1,TDRKH,GRIK1,IL12A,KIF5C,MAPT,SLCO1C1,CNOT4,NRCAM,NTRK2,PGAM2,CAMKV,CCDC40,FUZ,RPH3A,SMTN,LIMS2,FAIM2,TMCC1,SPTAN1,NPAS3,CLSTN2,SLC35G2,TRPC1,TMPRSS5,KCNAB1,GAN" Drug 3759_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "MTUS1,APBA2,ALDH4A1,CFLAR,SYNJ1,SYNJ2,BTRC,ARHGEF1,CBFA2T2,CDC42,SOCS6,TPP1,CPS1,SLITRK5,CTNND2,DCAF4,EDRF1,GPRASP1,RIMS3,DLG3,SGK2,CDKL3,C1QL1,GLYR1,TDRKH,HSF2,SCIN,INPP5B,ITPKA,VWA5A,MAPT,MATN3,MX1,NF1,SERPINI1,PRKAR1B,MAPK3,PRPH,RAD52,SH3BP2,DZIP1,SLC4A3,SLC1A7,SHANK2,SNCA,LHPP,ATP10B,KIAA1107,KIAA0930,RPGRIP1L,CRTC1,TIAM1,TPM1,ZKSCAN5,VLDLR,SPHK2,WNK1,SCG2" Drug 3987_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ADD2,ALAD,APAF1,CDC14B,PPP4R4,RASL11B,NRP2,GYG2,BTRC,LDB2,SCARB1,CDC42,CNTFR,AKAP7,CNTNAP2,RIMS2,DTNA,ABCC9,EFNB3,EPHA5,ETV1,PTK2B,FGFR1,PRELID3A,GABRA5,NEU3,GRIK5,ATXN2L,IL12A,KIFC3,MARK1,CLDN11,PDGFRA,ENPP2,PFKFB4,MAPK3,PTPRN2,BEND5,RGS4,MYH14,SYNDIG1,CSRNP3,ZNF821,FUZ,TNIK,NFASC,PHLDB1,COBL,DOCK9,CDK20,TRPC1,HIRA,VIPR2,ZNF24,ZNF154,WNK1,PARP6,DPF3" Drug 6407_DN 3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "DPF1,NME5,C1QTNF1,APBB2,DGKD,ARRB2,BTRC,CRLF1,CHN2,CLCN4,STOML1,RAB26,HOMER3,WHRN,CNTNAP2,SLITRK5,HDAC9,HDAC4,CNNM1,FAM13A,KIAA1109,SYT17,GPR17,ARHGAP19,KLF12,INPP5B,MDFI,MIA2,NEK1,NF1,CNOT4,PFKFB4,POLG,CNNM2,PTN,PTPRN2,FAM120C,CEP97,SUPT20H,ASAP3,ST6GAL1,COA1,ARHGAP26,SPART,ARHGEF9,TAC3,MCF2L,EXOC7,IQCE,TRIM2,CRTC1,ZMYND8,ZKSCAN5,VAV2,MICAL1,ZBTB14,NT5M,EPM2A" Drug 3714_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "DPF1,NME5,LTBP4,KCNAB2,PPP4R4,DNAH17,BMP7,CLDN10,USP2,CLTB,PDE4DIP,TRAPPC9,FRY,EPHB1,DLC1,GABRA2,SRCAP,GPD2,GRM1,GSTM5,HTR2A,ITGA7,KCNN1,KCNQ3,KIFC3,ADAM22,NCAM2,NDP,NPTX2,NRCAM,OPRL1,SNTG1,PNMA3,PRKAR1B,PROX1,ZCWPW1,RGS4,RORB,SALL1,SEMA6D,BCAN,RPH3A,SLC1A7,SLC12A4,ZNF334,SOX2,KDM4C,LHPP,VAMP1,ARC,SLC44A1,TNS1,CDK20,TRPC1,VIPR2,WIPF1,MKRN3,STMN4" Drug 6838_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "PLA2G6,CDC42BPA,ANK1,CDK13,SYNJ1,CACNA1A,CACNA2D1,ARHGAP33,CNOT8,SLIT2,CLCN4,TPP1,FAM149A,WHRN,RGS6,RIPOR2,SPOCK2,CTIF,DNAJC6,TMCC2,MBNL2,PLXNC1,HSD17B14,VPS13B,IGSF6,REEP2,DLC1,AFF2,GAD1,SEPT9,GNG3,GPER1,PCLO,GRM1,GUCY1A2,HNMT,KCND3,MOBP,ADAM22,MSR1,MYH6,ZNF862,PIK3CD,TNPO2,FAM120C,CCDC40,RGS12,RYR1,ASAP3,SLC14A1,MAPK8IP3,CEP68,SYT11,KAZN,WSCD1,TNS1,VIPR2,SPHK2" Drug 7329_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ASPHD1,NDRG2,NME5,APAF1,SEMA4G,RASL11B,SLC4A4,ALDH7A1,NRP2,SCAPER,BAIAP3,ARHGEF2,ADGRG1,CHRNB2,CSF1R,RGS6,NCAN,TBC1D5,MFAP3L,PARD6A,RABGAP1L,ATN1,DSCAM,EFNA3,MBNL2,ING4,RRAGB,CAMSAP1,C1orf61,AGAP2,DPYSL4,PRELID3A,MALT1,RAB30,GPR22,GRIK5,CACFD1,NR3C1,WIF1,VWA5A,SMAD1,MMP16,NDUFA5,CNOT4,PDE4B,MAPK10,RGS12,ZFHX4,EMID1,SYBU,PKNOX2,SLC11A1,LIMCH1,PLCB1,SEMA4A,PCDHGA1,AMACR,ST7" Drug 2997_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ABHD6,C1QTNF1,DOC2A,AMPH,BIN1,APAF1,APOC1,ATP1A3,MYOM1,CHN2,CLCN4,PCYT1B,TENM4,DGKG,HIPK3,EFNB3,TNK2,F5,FGFR1,FOXG1,SORBS1,B3GAT1,GAD1,GAD2,NEU3,ALDH1L1,GPM6B,GPR22,STMN2,GRIK1,GUCY1A2,HPSE2,HTR5A,KIT,SCG3,MYCN,NCAM1,NDP,PFKFB2,CCSER2,PURG,STRN3,PPP2R2B,PTPN13,GAL3ST4,RGS12,RYR1,PKNOX2,SLC12A4,TSNAXIP1,AJAP1,SYN2,SYT1,PCDHGA10,CRTC1,ZKSCAN5,FLRT2,PMEPA1" Drug 1730_UP Ethamivan [304-84-7]; Up 200; 18uM; HL60; HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ADCY6,ADD3,BIN1,AMT,ANK2,PPFIA1,ARRB2,CADM3,ARHGAP33,DLGAP1,TBRG4,ZFYVE9,IQCK,SEC31B,ECE2,SPOCK2,EFNB3,PLEKHO1,ZNF589,FGFR1,BAIAP2,SEMA4D,FLNC,AHDC1,GNG4,GSN,FICD,NXPH3,AGBL5,KCNN1,MID1,OCRL,MAPK3,GON4L,PTK2,PTN,RAB3IL1,CCDC40,SAFB,SATB1,ATXN2,NTNG1,BTBD3,SLC11A1,KDM4B,WDTC1,ARHGEF9,PLCB1,ARHGEF12,GPR161,THRA,CHST5,TMPRSS5,FLRT1,NPDC1,LAMP5,GDPD5,MPPE1" Drug 2575_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "AP2A2,AMH,ANK3,PKP4,MARK4,B3GALT2,CFLAR,CA12,THSD7A,KALRN,CAPN3,NEURL1,CHGB,CHRNB2,CLCN4,ABI3BP,NRG2,DBT,SPEG,CACNG2,PTK2B,OLFM1,CAMSAP1,SEMA6C,CAMKK2,GABRA5,GAP43,GPD2,PRUNE2,TJAP1,ITGAM,KIF5C,LAMA2,NOVA2,KCNK10,PAX6,PDE3B,PDE4A,PDE4D,PLP1,MINDY2,PPP5C,GDPD2,RGS12,MYH14,TMEM206,CCDC102B,ZSWIM8,ZC3H13,RAP1GAP2,DNMBP,PSD3,ICAM5,PARD3,RBFOX2,FLRT1,SPHK2,PHTF2" Drug 6246_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "PLA2G6,LTBP4,ALK,DOC2A,AMPD3,APP,ATP2A2,AZGP1,SYNJ2,SCAPER,SGCE,CA12,PLEKHB1,ZFYVE9,STOML1,RABGAP1L,RCAN1,ACSL4,SRCAP,GLYR1,GLS,SLC2A6,MUM1,HLF,IL6ST,INPP5B,ITPKB,KCNH2,MAP4,ADAM11,MIA2,NF1,NUMA1,OLR1,KCNK10,RETREG1,RAB3A,RAB5B,ZCWPW1,KCTD17,GSTCD,RPS6KA2,SH3BP2,BCAN,ZSWIM8,ZC3H13,NCDN,MLC1,VAMP1,ATP11A,TCF7L2,ATP13A2,CABIN1,HIRA,VIPR2,LMF1,HPS4,TIGD6" Drug 3623_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ACTN2,ADRA1D,SEMA4G,PRX,BAIAP3,RHBDL1,ZFYVE9,CSF1,CHD5,PHYHIP,ELMO1,GSDME,SMG7,SRGAP3,HS3ST2,TNK2,OLIG2,KCNMB2,ERCC2,KIAA1109,FHL1,FOLR2,SIGLEC8,CPLX2,ADAM28,GNAO1,GRIA4,GRIK2,GSTM5,ITGA7,KCNMA1,KIF5A,MAPT,NCF2,NELL2,NEUROD2,NPR2,OMG,KCNK10,POU3F2,VPS13C,RAD52,KHDRBS2,ASIC4,MRAS,SH3BP2,ASAP3,SLC11A1,SLCO1A2,TNIK,SOX10,ATP10B,MAPK8IP3,DOCK9,THRA,TRH,FLRT2,AP3B2" Drug 6086_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ADORA1,AGT,C1QTNF1,SEMA6A,LTBP4,ANK1,CDC14B,PLA2G4C,CCDC181,CDK5R2,CAMK2B,DNAJB5,COL9A3,SLC4A7,MYRIP,CSF1,GREB1,NOS1AP,LRRC23,ERBB4,EFS,PTK2B,DCTN2,DPYSL4,ERAP1,SIGLEC8,DISC1,RND1,GRM7,AP4S1,KLF12,HPSE2,IFI16,KIFC3,LMO1,TAGLN3,NF1,PENK,RETREG1,MTRF1L,LRP12,PACSIN1,PPP5C,TRIM68,RGS12,NUDT11,TCP11L1,ST6GAL1,RPH3A,ARHGEF40,SLC11A1,SPTAN1,SYT5,HEY2,TRIO,SLC17A7,ITM2C,JPH3" Drug 4579_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ADD2,ADRA1D,AP2A2,SEMA7A,APBB2,AZGP1,CACNA1I,LDLRAD4,ARHGEF2,CRLF1,CBARP,EPS15L1,AKAP6,CREM,PDE4DIP,ARHGEF4,USP6NL,DSCAM,ING4,COQ7,REEP2,KIAA1109,DPYSL4,TBR1,LILRB4,GPD2,CNTRL,CACFD1,GRM8,GUCY1B1,ICA1,ITGA7,KCNF1,LIG4,MEF2C,TAGLN3,CNOT4,NPY,OLR1,PDE4D,PDGFRA,PFKFB4,LRRN3,PRKAR1B,MAPK10,RAB3A,ZNF821,HECW1,THSD1,TBCEL,TRIM2,AHCYL2,TK2,TPM1,CHST5,ZNF24,ZNF225,PARP11" Drug 5432_UP Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ASIC1,ACTN2,ADRA1B,ALCAM,AMPD3,AMPH,PRX,PPP4R4,CACNA1G,BAIAP3,CACNA1D,CACNA2D1,CD86,CDH18,EPS15L1,ZFYVE9,SLC24A2,CYBB,SLC12A6,DTNA,FRY,KCNMB2,REEP2,FGF1,PDLIM5,ALDH1L1,PRUNE2,LPAR4,GSTM5,CELF3,SCRG1,ICA1,IRF8,MDFI,MMP16,NEFM,NF1,NNAT,NPPA,OPCML,CDK18,CDK14,CEP41,PTPRO,RAB3IL1,RAD52,RGS12,RORB,WDTC1,ZNF423,BEX1,POPDC3,ROBO3,PCDHA5,HEY2,UCHL1,DNALI1,SLC17A7" Drug 2395_UP Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "MTUS1,SRPX,BCAR3,CDC42BPA,APBB2,PRX,PDE8B,ASPH,C5,RUNX1T1,CDH2,RAB33A,ABI3BP,CREM,SH2B1,HAPLN1,SV2A,DLG3,EFNB3,CELSR3,MTSS1L,FER,KIAA1109,CAMSAP1,AGAP2,GAB1,C1QL1,IL1RAPL1,KLF12,ICA1,NELL2,NFIX,NPPA,OLR1,MAPK10,PTAFR,RGS3,SEC61A2,KCNIP1,ZNF821,ZNF365,LIMS2,FAM214B,SLC20A2,DOP1A,KDM4C,UNC5B,RBM26,TEX15,KCTD2,TNS1,TPM1,TRPS1,VAV2,VGF,BEST1,SPHK2,REEP1" Drug 3056_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ABAT,SPARCL1,ANK3,B3GALT2,MYOM1,MPDZ,SYNJ2,BAIAP3,SLC16A4,REPS2,ARHGAP33,SOCS6,CHI3L2,RAB26,PDE4DIP,CTNND2,NOS1AP,DNAJC6,NTM,ST8SIA3,PLEKHA1,EPB41,EFS,RRAGB,OLFM1,BAIAP2,DKK3,GABRA3,GAD1,SIGLEC8,GPM6B,GRIN2C,GPR45,HTR5A,MAPT,MOBP,ADAM22,MYH3,NCAM1,PCDH9,PDGFRA,MAPK8,NUDT11,MAP6D1,SCN7A,SLC1A3,SLN,IZUMO4,ASTN2,TRIM2,PHF24,TK2,RIMBP2,TRO,TRPC1,LMF1,VSNL1,KCNAB1" Drug 2520_UP Tetrandrine [518-34-3]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "MTUS1,C1QTNF3,ALK,CDC42BPA,APAF1,PPP4R4,ASPH,SYNJ1,LDLRAD4,HIP1R,SCARB1,SYNGR3,SOCS6,CREM,DZIP3,EDRF1,HS3ST2,SLC12A6,HIPK3,C3orf18,KIAA1109,SIGLEC8,ALDH1L1,PCDH17,RND1,GPR22,GUCY1A2,ATXN2L,HMGCR,IL6ST,KCNN1,LSS,MEF2C,CD200,ADAM22,SLC11A2,NRCAM,PFKFB4,CCSER2,PPP5C,GAL3ST4,ZFHX4,MYH14,SEMA6D,SH3BP2,PREX2,SLC11A1,SHANK2,SOX10,PEG10,DNMBP,RPGRIP1L,SLC19A3,AHCYL2,TLR4,XRCC4,EVI5,PHTF2" Drug 6167_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "SYN3,ACTN2,SPARCL1,BIN1,CNTNAP1,CDK10,PDE8B,SLC4A4,PROM1,SYNJ2,BTRC,CACNB4,LARGE1,DLGAP2,SLIT2,CSNK1E,DAPK1,DLG3,CDON,ABCC9,EFNA3,EFNB3,MBNL2,SORBS3,RASGRP2,F5,REEP2,FGFR1,SEPT9,INPP5K,GFRA1,GPD2,GPM6B,GRIK5,KCNB1,KPNA5,MDFI,MSR1,NF1,NOVA2,NPPA,CLDN11,CCSER2,TNPO2,PTPRB,PTPRN2,SEC61A2,MYH14,ASIC4,GALNT10,FRMPD1,CPEB3,SHANK2,SP4,SYT5,IQCE,RIMBP2,RPRM" Drug 3619_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ADORA1,SEMA6A,MRTFA,CACNA1I,CFAP410,CAMK2G,HIP1R,USP2,INA,CDH2,TCEAL2,CSF1,MICAL2,DOCK4,DCT,RUSC2,SPOCK3,DRD1,ATN1,EFNB3,RASGRP2,ERCC2,AFF2,SORBS1,FUT9,SRCAP,RND1,LILRA2,GRM1,SYNPO,IL11RA,JAK2,KCNC1,KCNH2,KCNJ5,KCNN1,KHK,MAPT,NEUROD1,NPY,PFKFB2,PIK3CD,NUDT11,RAVER2,EMID1,ASAP3,DZIP1,SLA,HECW1,ZBTB43,ARC,SYN2,TEX15,GPR161,LAT2,CA10,MPPE1,DPF3" Drug 4759_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "ASIC1,ADCY6,C1QTNF3,ALK,AMPD3,APAF1,APC,APOC1,PPP4R4,BRINP2,CADM3,NRP2,CFLAR,CFAP410,CACNG1,HAP1,SOCS6,NECTIN3,AATK,CSF1,SRGAP3,DMPK,ATN1,TENM1,VPS13B,EPHB1,CDHR1,FGFR3,FOXG1,FUT9,TBR1,FYB1,GPR75,GPD1,ICA1,KCNH2,KCNJ5,LAMA2,AFDN,SLCO1C1,NPY,MAPK7,RPS6KA2,SCN8A,SH3GL3,BCAN,RPH3A,KANSL3,LIMCH1,UNC5B,NPAS3,ATP10B,AJAP1,TBL1X,ZEB1,VIPR2,SYNC,SLC30A3" Drug 4095_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.40E-06 6.85E-02 3.37E-05 3.84E-04 58 200 "AMH,AQP4,ARRB2,PDE8B,ATP1A3,CBFA2T2,SCARB1,CLCN4,DNAJB5,LY86,HOMER3,CNTFR,IQCK,AKAP5,TCEAL2,AATK,PDE4DIP,RIMS2,CTIF,BRINP1,MFAP3L,ST8SIA3,AASS,COQ7,ZNF589,FGFR1,FLT1,C1QL1,ATXN2L,KCNMA1,KIFC3,MAPT,MIA2,TAGLN3,OPCML,PDE4D,EPN1,PLXNB1,PPARA,RGS10,DOCK10,SLC1A7,SNCA,TMCC1,KDM4C,TROVE2,MCF2L,PCDHGA10,PCDHA5,GPR161,TK2,TPM2,KLC2,XRCC4,ZIC3,WNK1,NT5M,SEMA3B" Drug ctd:C482199 "lipopolysaccharide, E coli O55-B5" CTD 1.43E-06 7.01E-02 3.45E-05 3.92E-04 335 1687 "SERPINA3,ABR,ADD3,USP31,PWWP2A,ADRB2,KIDINS220,NLGN4X,CASKIN1,TBC1D14,WDR35,CC2D2A,ABCD2,LTBP4,PITPNM2,AMH,USP28,APBB1,EPB41L5,CACHD1,LRRC4C,BCAS1,USP37,SEMA4G,ZFYVE28,CHRD,NCOA1,ATP2B1,ATP2B2,ATP2B3,CADM3,CARMIL3,ADAM15,KSR1,ARHGEF7,C1QC,MYRF,FOXK1,CACNA1A,CAMK2B,CANX,CAST,CH25H,SPAG9,PRC1,ARHGEF25,CBLN1,SHISA7,CD86,ARHGEF1,AP4M1,ARHGEF2,CDC25B,IGFN1,CLGN,NUMBL,CACNA2D2,ADGRG1,RCBTB2,SLC22A6,RAB28,ZFYVE9,KIAA1549L,CLU,MAP4K4,COL4A5,COL9A1,MAGED1,COX4I1,IGDCC3,SEC31B,CRHBP,CREB5,AKAP12,CRY2,CS,CSF1R,FEZ1,MICAL2,PLXNA4,ARHGEF4,ECE2,NOS1AP,CYBB,MYADM,CENPL,KIAA0586,ZBTB24,FBXL5,ALKBH8,DLG4,DNM1,DMPK,DNAH9,RPS6KL1,DNM2,SHANK1,ABI1,RCAN1,TOM1,DNAJB6,ANKRD46,SGK2,KLHL5,TMTC1,CELSR3,EGFR,MBNL2,ELAVL2,RGS17,OLIG2,MTSS1L,GPHN,VPS26C,RASL12,FABP7,ATP8A1,PRMT5,GORAB,TMEM164,FGR,PRKAG2,CAMSAP1,HPCAL4,PCYOX1,SYNCRIP,SGIP1,SLC37A3,POMT1,HVCN1,USP16,STAG2,MEGF11,SALL3,GHDC,IQGAP2,ERAP1,TMEM8B,GCK,ALDH1L1,GDF9,AHDC1,GGT7,GGT5,GHR,PPARGC1A,GJB1,RUNDC3A,KDM2B,LILRB4,GPD1,GPD2,TDRKH,STON1,GRIK3,ADAMTS13,GRIN1,ZBTB49,RASSF8,HPS5,ZHX1,HRH3,NCKAP1L,HMGB1,HSP90AA1,SHISAL1,MYLK2,IGF1,IGFBP1,KNDC1,KIAA1755,IL12A,ZNF678,INPP5B,NME9,JAK2,KCNH2,KIF2A,LRRC4B,PIK3AP1,MAOB,MAPT,MATN2,MEIS2,KITLG,AFF1,XRRA1,MOV10,THYN1,MX1,NCF2,NEK1,NFE2L2,ALDH1L2,NOS1,SLC11A2,SMIM11A,HCN1,NUCB2,SETD4,OPHN1,PCSK5,PDE4B,PDPK1,GNG2,ABCB1,SERPINE2,PKM,PLCD1,PLEC,ASPDH,PURG,SH3KBP1,POU3F2,PPP5C,PRKAB2,PRKACB,PRKCZ,MAPK3,MAPK8,LRRC49,LAMA1,DEF8,WDR25,PSMD13,PTCH1,ANKHD1,ZIK1,PTPRG,PEX2,QDPR,RAP1GAP,RDX,RFX3,ZDHHC4,RNASEL,RNH1,TMEM206,TMEM100,LRRK2,CLIP1,RXRA,AP1AR,DGLUCY,SATB1,ATXN1,HOGA1,ASRGL1,DOCK10,SHMT2,MAGI3,CHD9,CLSTN1,SLC2A5,RUFY2,ARHGEF40,ZNF334,SLCO1A2,SMARCA4,CDK5RAP2,SNCA,KIF13A,PDZD2,SOX2,TNIK,ZSWIM8,SPP1,ZNF423,IQSEC2,DDN,SRPK2,CAMTA2,SMOC1,SSPO,DIP2A,ADHFE1,GANAB,FAM168A,SYT11,ZC3H4,SYNE2,SYP,MMS19,TACC1,SEMA4A,CAMTA1,TAF6,WWC1,AGTPBP1,EHBP1,DMXL2,TRIM2,USP22,SZT2,SYNE1,OBSL1,TF,TMEM121,TJP1,ICAM5,DDHD1,TLR4,R3HDM1,CABIN1,NR2C2,TRIO,NTSR2,SSBP2,TTPA,TMEFF2,DNAJC12,VAV1,CCDC14,TBC1D15,VSNL1,WIPF1,XPO1,ZNF23,SPHK2,ZNF142,ZBTB38,ZFAND5,UPF3A,WNK1,SLC30A4,NT5M,SCG2,VPS35L,SLC17A7,HRASLS,FZD3,MARCH8,RTN4,PAK5,SLC39A12" Drug 3291_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.44E-06 7.07E-02 3.48E-05 3.96E-04 56 191 "SERPINA3,ACTN2,C1QTNF1,SRPX,ALK,SEMA7A,APLP1,ALDH4A1,CAMK2B,ARHGAP33,FOXN3,ARHGEF6,WHRN,CRMP1,ATRNL1,CHD5,VCAN,CNTNAP2,CTIF,TRAPPC9,DMTN,LRRC17,FHL1,SIGLEC8,GLS,PCSK1N,GNG4,ADAMTS13,GRIK5,GRM3,KCNJ5,KCNQ3,VWA5A,MAP4,MATN3,MEF2C,ADAM22,CLDN11,PPP2R2B,CEP41,MAPK8,PTAFR,MYH14,TCP11L1,SYNDIG1,SLC6A8,SLC9A5,SNCA,WDTC1,SOX10,CLSTN2,PHLDB1,ABCC8,TAC3,PDIA2,NLRP3" Drug 6658_DN Luteolin [491-70-3]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.44E-06 7.07E-02 3.48E-05 3.96E-04 56 191 "ADRB2,NME5,LGR5,ZBTB10,BCL7A,CDK5R1,BTRC,CHM,CLCN3,CLCN4,NIPBL,HOMER3,GIT2,RHOBTB1,DPH1,SIDT2,FAM13A,TUBD1,ANKMY1,FYN,GAD1,ZMYND11,B4GALNT1,GUCY1B1,IFI16,INPP1,KHK,KIF5C,MAPT,NAP1L3,NDP,NEK1,NF1,PLCD1,SAMD9,WDR25,RGS4,ITSN1,SH3GL3,DOCK10,SLC20A2,SRPK2,MAPK8IP3,SYT1,SATB2,AHCYL2,DNAH7,TMEM121,GPR161,TIAM1,NR2C2,XRCC4,SMIM8,ADAMTSL3,ZNF248,TIGD6" Drug 7547_UP Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.44E-06 7.07E-02 3.48E-05 3.96E-04 56 191 "ARID1A,EPB41L5,NCOA1,MPDZ,BTRC,CHM,TAOK2,DNAJB5,RAB26,CRY2,CTH,GPRASP1,DAPK3,CNIH3,KBTBD11,DPH1,TOM1,LRRC23,REEP2,FGFR1,TRMO,FYB1,SRCAP,GPM6B,KLF12,ITPKA,LIG4,MBD1,LYRM9,NDP,SLC11A2,PALM,PTN,PTPRE,FAM120C,SUGCT,ZNF671,RASA3,ASAP3,LIMS2,MYH15,LIMCH1,DOP1A,DBNDD2,ZBTB43,SRPK2,POGZ,SEMA4A,OBSL1,TIAM1,TNS1,TRIO,XRCC4,SPHK2,EMSY,HPS4" Drug CID003035711 DETC-MeSO Stitch 1.45E-06 7.13E-02 3.50E-05 3.98E-04 19 39 "ALDH7A1,AASDH,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug 6316_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.48E-06 7.23E-02 3.55E-05 4.04E-04 54 182 "ABAT,ADRB2,NME5,EPB41L5,PPFIA3,SHROOM2,CDC14B,ARNTL,MARK4,BRINP2,ST3GAL5,HIP1R,USP2,NRXN3,WHRN,ABCG1,PDE4DIP,CTH,DNAJC6,JAKMIP2,C2CD2L,PLPPR4,EFNA3,RGS17,TAOK3,DPYSL4,NBEA,FYN,GLS,STON1,GUCY1B1,DIPK1A,KIF5C,MAPT,PCDH9,SERPINI1,RETREG1,PRPH,PTCH1,ENOX1,RGS4,FBXW7,SH3GL3,TNIK,ZCCHC24,SPTAN1,THSD1,RGL1,SYT11,SYT1,TRIM2,SSBP2,DNAJC12,TRIM9" Drug 3075_UP Cantharidin [56-25-7]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.48E-06 7.23E-02 3.55E-05 4.04E-04 54 182 "ACTN2,ANK3,DDO,SEMA4G,PLA2G4C,CCDC181,CDK5R1,CA12,INA,MYOM2,TAOK2,CREM,SPOCK2,ST8SIA3,EFNB3,EGR3,EIF5,LRRC23,ERBB2,C1orf61,CSPG5,BRD8,RND1,GNG4,GRK4,GUCY1A1,PADI2,SYNPO,KIF5C,MAP4,MBP,MOBP,NHLH1,PURG,PMP2,PPARA,PPP2R2B,LRRN3,PRPH,TRA2B,SCG5,SHANK2,TNIK,DDN,VAMP1,ARC,ANKRD28,TAC3,TBCEL,ZNF34,HEY1,TJP1,TRPC1,SEMA3B" Drug 2451_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "MTUS1,APBB2,RIPK1,MPDZ,ARHGEF7,CACNA2D1,HIP1R,SPAG9,LARGE1,CHN1,CNOT8,EPS15L1,ZFYVE9,SULT4A1,COL9A3,MICAL2,RIMS2,TBC1D5,MFAP3L,DLG3,OPTN,MBNL2,CEND1,FER,KIAA1109,ANKFY1,NBEA,TRAF3IP2,GALC,POLL,ATXN2L,HSF2,KCNJ5,KPNA5,LSS,AFF1,NNAT,PDGFRA,PLCD1,PTPRN2,GAL3ST4,MAP6D1,SCN8A,FNDC3A,SLC12A4,PEG10,SRPK2,SS18,NXT2,MAPK8IP3,SEPT8,PHLDB1,RPGRIP1L,SZT2,TEX15,ZNF24,NUP214" Drug 2296_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADD2,ADORA2A,ALK,DOC2A,CDC42BPA,GAS7,APLP1,AQP4,SEMA4G,PDE8B,CADM3,FGF17,CFLAR,HIP1R,CHN2,WHRN,CRY2,HDAC9,DTNB,EFNB3,MTSS1L,ERCC2,DLC1,FGF12,GPR153,GPM6B,GRM3,SHISAL1,ITGAM,KCNJ5,MID1,CD200,NEFM,KCNK10,SERPINE2,MAPK7,RELN,FAM120C,ZNF493,RGS12,KCTD17,SEC61A2,MYH14,EMID1,MRAS,SLC2A5,PKNOX2,SLC9A5,KDM4B,HECW1,ARC,SYT5,TBCEL,DAAM2,FAM155A,MKRN3,SPHK2" Drug 3394_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "RALGAPA1,ADORA2A,KIAA1324,N4BP2L1,CFLAR,CACNA1I,HIP1R,RHBDL1,RUNX1T1,NEURL1,ARHGEF2,FAM169A,DGKG,DAPK3,TRAPPC9,SNX29,PLXNC1,TNK2,ERCC2,REEP2,KIAA1109,FHL1,GAD1,SIGLEC8,DISC1,GRB10,GRIK5,ICA1,INPP5B,KIT,MAP4,MEF2C,MOBP,ADAM22,MX1,POU3F4,PPP5C,CEP41,PTHLH,CCDC40,RFX2,SYNDIG1,BCAN,RPH3A,PKNOX2,ARHGAP26,NCDN,PCDHGA10,SYNE1,TMOD1,R3HDM1,XRCC4,MVB12B,PLSCR4,EPM2A,PHTF2,SENP7" Drug 3703_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "C1QTNF3,MRTFA,APBB2,GAS7,APP,CDK10,CDK13,MTMR2,MYRF,BAIAP3,KYAT1,NRXN3,KIAA1549L,IQCK,IFFO1,CREB5,SLITRK5,SPOCK2,CNIH3,PLXNC1,TNK2,STX2,FGFR1,FOXG1,PRELID3A,OGA,FYN,TRAF3IP2,ERAP1,GCNT2,SRCAP,PCDH17,GPR17,BACH2,ICA1,TJAP1,KCNMA1,ADAM22,NDP,NDUFA5,NPR2,SNTG1,RETREG1,CEP41,RAB3A,RAD52,ZCWPW1,DZIP1,PEX26,ARHGEF40,ARHGAP26,COLGALT2,KAZN,MCF2L,TCF4,THRA,LAT2" Drug 6060_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ACTN2,ADORA1,AMPD3,BIN1,CDK13,SLC4A4,FGF17,CALB1,CAMK2B,CLCN4,TENM4,SDC3,TRAPPC9,ATN1,ST8SIA3,EDNRA,LRRC23,MTSS1L,ZNF589,BAIAP2,NSG1,DLL3,FYB1,GAP43,GPER1,CACFD1,GRM8,PTGDR2,SYNPO,IFI16,KCNMA1,KCNN1,LMO1,MEF2C,ADAM22,PDE4D,PRRX1,LRRN3,PRKCB,PLPPR1,PTX3,KHDRBS2,ZMAT4,RFX2,RGS12,CCDC88A,CXXC4,KDM4B,DOK5,ZSWIM8,PEG10,TRIM2,CRTC1,TNS1,VIPR2,SPHK2,SLC17A7" Drug 2236_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "MRTFA,BIN1,GAS7,APOC1,ZSCAN18,N4BP2L1,CFLAR,SYNJ1,LDLRAD4,BTRC,CAMK2B,GPR37L1,RAB33A,SULT4A1,FAM149A,WHRN,ARHGAP24,RABGAP1L,EFNB3,MBNL2,IGSF6,KIAA1109,FGF12,FGFR1,DLL3,FYN,GATM,ALDH1L1,MSL3,GNG3,GRIK2,GUCY1B1,PTGDR2,IRF8,IL6ST,SMAD1,MAP2,MAP4,MOBP,NELL2,NUMA1,PLCD1,STRN3,PACSIN1,SAMD9,RAD52,KLHL11,MYH14,RASA3,DOCK10,VAMP1,THRA,R3HDM1,CABIN1,TNS1,TPM2,ITM2C" Drug 5073_UP Loracarbef [121961-22-6]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "TTYH1,ADD2,PLA2G6,ALK,AMPH,NRP2,SCAPER,BAIAP3,CALB2,CAPN3,DGKI,CHGA,CHN2,CABP1,CRYBB1,AATK,SUSD5,NOS1AP,RIPOR2,TOX,RIMS3,ABCC9,EDN1,MRNIP,CALCRL,EXTL1,AFF2,EFCAB2,ERGIC3,SIGLEC8,POLL,GRM1,GRM7,HLF,ICA1,KCNC1,ADAM22,PDE4B,GPR85,PFKFB4,CAMKV,RETREG1,PACSIN1,PROX1,DCHS2,PID1,RGS12,EMID1,PAQR6,NTNG1,SLA,ZHX3,ZNF225,NT5M,PARP6,SEMA3B,FAM13C" Drug 2569_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "NDRG2,KIDINS220,C1QTNF1,APBB2,ATP1A3,BMP7,BAIAP3,CDH8,CDO1,ABCG2,DNAJB5,HOMER3,CREM,PDE4DIP,SLITRK5,CTNND2,EDRF1,RABGAP1L,ATN1,E2F5,MBNL2,OLIG2,COQ7,ANKMY1,C1orf61,SIGLEC8,GATM,PRUNE2,PCLO,GUCY1B1,ITIH2,MYH3,ZNF862,NAP1L2,PPARA,CEP41,MAPK8,KLK6,PTAFR,ZFHX4,TMEM206,EMID1,RXRA,SMPD3,ASAP3,PKNOX2,SLC11A1,SNCA,DOP1A,TNIK,AHCYL2,DNAH7,ZNF34,TIAM1,TRO,MPPE1,SSPN" Drug 6301_UP Clopamide [636-54-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADD2,KIDINS220,C1QTNF3,LTBP4,PKP4,PTCH2,N4BP2L1,GYG2,CACNA2D1,CAMK2A,ARHGEF2,ARMC8,CREB5,VCAN,PDE4DIP,DCAF8,TOX,ARNT2,DSCAM,EFNA3,PLXNC1,ELAVL3,COQ7,DMTN,RASGRP2,STX2,APC2,ZNF589,PDLIM5,DLL3,PNMA2,DENND2A,GAD1,STON1,CNTRL,PTGDR2,ATXN2L,IL6ST,TM6SF1,MX1,KCTD15,CNNM2,PTCH1,PTPRN2,RAB3A,RGS12,MYH14,SCN2B,STUM,CCDC88A,SLC11A1,FAIM2,ARHGEF9,KIAA1107,CHST8,R3HDM1,PRDM2" Drug 4409_UP Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "APLP1,LGR5,SEMA4G,ASCL1,DNAH17,BCL2L2,BAIAP3,CACNA1D,HIP1R,RUNX1T1,TPP1,STOML1,CLTB,SULT4A1,AKAP5,MYRIP,CSF1,VCAN,RIMS2,SHANK1,TOM1,ABCC9,MBNL2,KIAA1109,OLFM1,ANKFY1,GAD1,GRM2,AP4S1,KCNB1,KCNJ5,VWA5A,AFDN,NPY,NPPA,NPTX2,PDE1C,PDE4B,CDK14,EPN1,POU3F4,ZMAT4,RPS6KA2,SEMA6D,ZNF821,RASA3,SH3GL3,ASAP3,SLC6A9,SLN,RIMS1,CDK19,TROVE2,AJAP1,TCF4,DOCK9,TRPM2" Drug 5760_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADD2,MRTFA,APP,EIF4G3,ST3GAL5,KRIT1,CDH10,RAB28,CLU,HOMER3,ARMC8,AKAP5,CRMP1,PHF14,EDIL3,HEYL,PLXNC1,ING4,ZNF391,KIAA1109,SORBS1,STAU2,GABRA2,SYT17,GFRA1,COPS8,FERMT2,PTGDR2,JAK2,KCNJ5,MGAT3,LYRM9,NOVA1,OXTR,PDE4D,PTCH1,PTPRN2,RBBP6,RGS12,RNASEL,CSRNP3,STUM,SUPT20H,HSPA4L,FNDC3A,CCDC88A,PDZD2,SPTAN1,ARC,SYT1,COBL,SEMA4A,MCF2L,RPGRIP1L,EPM2A,FAM13C,SENP7" Drug 1184_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "PLA2G6,MRTFA,APOC1,ARNTL,PDE8B,CCDC181,MTMR3,CACNA1A,CD86,CBFA2T2,NMT2,CREM,DBT,RUSC2,GSDME,EEF1A2,HIPK3,FAM13A,MBNL2,PLEKHA1,ING4,RASGRP2,F5,ANKFY1,INPP5K,AHDC1,GLYR1,POLL,MEF2C,MPP2,MX1,P2RX7,KCNK10,POU3F2,MINDY2,PTAFR,RGS10,MRPS18A,RPS6KA2,TRAPPC13,GALNT10,ASAP3,SLC11A1,ZCCHC24,IQSEC2,LHPP,SRPK2,ZC4H2,FCHO1,MAPK8IP3,CEP68,STXBP1,PLCB1,KIAA1107,TNS1,NPDC1,GAN" Drug 3383_UP Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "FZD9,ADRA1B,PLA2G6,ALCAM,ALK,KCNAB2,ARHGDIG,RASL11B,SLC4A4,CADM3,BCL2L2,GYG2,GPR37L1,TPP1,COL9A3,ARHGEF10,CHD5,SPOCK2,FYN,GAD1,SIGLEC8,GRIK5,NR3C1,GRM1,PRDM5,GSN,GSTM5,AP4S1,ITIH2,KCNMA1,MAN2A2,MATN3,KITLG,MX1,OPCML,PFKFB2,PLXNB1,MAPK7,PTAFR,PTN,RAD52,TMEM206,SH3BP2,ST6GAL1,RPH3A,SLC11A1,SLCO1A2,LIMCH1,SOX10,ZC3H13,ATP10B,PCDHGA10,SYNE1,XRCC4,KAT6A,ADAMTSL3,SENP7" Drug 5536_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "DPF1,ABR,ABHD6,ADRA1D,AP2A2,BIN1,ANK1,APBA2,ATP6V0A1,CDH10,ZFYVE9,C2CD2,LRIG1,RIMS2,DCAF4,SEC14L5,TOX,RIMS3,JAKMIP2,HP1BP3,TMCC2,EFNB3,LPAR6,LRRC23,CDHR1,NRN1,PTK2B,FAM49B,GNG3,ADAMTS13,ATXN2L,HPCA,IL12A,LAMA2,MBD1,NCAM1,NFYA,PLEC,STRN3,LRP12,PPARA,SAMD9,CARF,RPS6KA2,SEMA6D,SH3BP2,SLC2A5,HECW1,ZBTB43,CEP68,TAL1,TK2,XRCC4,SLC30A3,WNK1,MAP3K12,SLC17A7" Drug 4482_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ALK,AMPD3,APC,BCAS1,PPP4R4,ATP1A3,NRP2,CFLAR,GYG2,CAMK2B,CDH8,PLEKHB1,EPS15L1,STOML1,HOMER3,PICK1,TCEAL2,NCOR2,MICAL2,FAM131B,ATN1,EDNRB,LRRC17,ALDH1L1,GPM6A,CACFD1,GRM7,PTGDR2,ITIH2,KCNH2,VWA5A,MAN2A2,NPTX2,PALM,PC,PDE4A,GPR85,PFKFB2,SNRK,ZSCAN32,PTPRH,FAT4,ROM1,TCP11L1,CNKSR2,ARHGEF40,SHANK2,ZHX3,AP4E1,TNS1,CHST5,ZKSCAN5,FLRT2,VAV1,VAV2,SPHK2,KCNAB1" Drug 4619_DN Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ARID1A,ADRB2,AMT,APBB2,STX16,ADGRB2,SCAPER,CACNA1I,SYNGR3,PLEKHB1,KIAA1549L,SLC4A8,FAM131B,KIAA0513,HP1BP3,SGSM2,KBTBD11,DNM2,FEM1B,EGFR,DLC1,FER,KIAA1109,AFF2,B4GALNT1,SIGLEC8,GBX2,GCNT2,GPR17,CACFD1,DIPK1A,LIG4,MAPT,MT1M,MX1,PAK3,PDE1C,PPARA,PRPH,CNTLN,PTPRB,PEX5,ZSCAN2,RAB3IL1,RGS3,FBXW7,TMEM156,ASAP3,SLA,SNCA,TSNAXIP1,IQSEC2,ZBTB43,CHST8,XRCC4,ZNF711,NAV3" Drug 3175_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "SYN3,ALK,CNTNAP1,APP,PRX,ARHGDIG,ASTN1,CACNB4,HAP1,CDC42,EPS15L1,RAB33A,CLTB,AATK,JAKMIP2,FAM13A,C3orf18,CORO2B,OLFM1,SORBS1,FUT9,GABRA5,DISC1,PCDH17,STMN2,GRM1,KCND3,MAP2,ADAM22,NPY,PCBP3,PAH,TREM2,PALM,PDE3B,PDE1B,GPR85,PLXNB1,MAPK7,CCDC40,TRIM68,ASAP3,SLC1A2,SLC6A8,SLC9A5,FAIM2,TSNAXIP1,UNC5B,PEG10,JMJD6,ADGRL3,CHST5,WIPF1,ZNF45,NT5M,DNALI1,ITM2C" Drug 6447_DN Metyrapone [54-36-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "BRAP,SEMA6A,APC,EPB41L5,CDC14B,ARNTL,STX16,RAB28,NRG2,CHD1L,ENTPD4,GREB1,TOM1,EFNB3,IRAK4,ENO2,ANKMY1,FGFR1,BAIAP2,TRMO,PRELID3A,MSL3,HSF2,VWA5A,MAP4,MAPT,ZNF862,SLC11A2,RC3H2,PSMD13,ZSCAN32,RIPOR1,RAP1GDS1,RGS10,RGS12,NEK11,WLS,ZFP30,BCAN,CXXC4,ERC1,TROVE2,CEP68,DIP2A,ARC,SEMA4A,MCF2L,KIAA0930,TMOD1,HIRA,FAM155A,XRCC4,ZNF74,UPF3A,MAP3K12,HPS4,SMIM8" Drug 3760_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ASIC1,PLA2G6,AMPD3,APBB1,APOC1,ARRB2,ASPH,ALDH7A1,BMP7,SYNJ1,SYNJ2,ARHGEF7,CFAP410,SCARB1,CHM,LY86,WHRN,SLC4A8,CTNND2,RIMS3,MFAP3L,SMG7,EXOG,CNNM1,ING4,ETV1,FGFR1,FOXG1,PRELID3A,TMEM8B,DISC1,USP19,GLI2,POLL,GPM6B,RASSF8,INPP5B,JAK2,LIFR,NDP,PPARA,PRPH,CNNM2,SUSD4,RGS7,SNCA,FNBP1,UNC5B,TROVE2,THSD1,PHLDB1,COBL,ZEB1,ARHGEF12,TNS1,NT5M,TIGD6" Drug 4368_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ABHD6,ADRA1D,PLA2G6,AMT,APBB2,APC,APP,ARNTL,CFAP410,SCARB1,CLGN,STOML1,PICK1,CNTFR,AKAP12,ABCG1,CSF1R,EDRF1,DBN1,RUSC2,EFNA3,ERCC2,FGF13,SCARA3,AGAP2,GCNT2,GPD2,STON1,GPR37,GSN,HNMT,KCNH2,LMO2,MMP16,NF1,CNOT4,GRAMD1C,RGS10,SUPT20H,SH3BP2,SMARCD3,IFT122,KIF13A,ZCCHC24,KDM4C,IQSEC2,CLSTN2,PHLDB1,STX1A,PLCB1,ROBO3,KIAA1107,TRIM2,FLRT2,SPHK2,KAT6A,NUP214" Drug 4416_DN Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "AK2,DOC2A,AMH,AMPD3,GAS7,APOC1,ASPH,CADM3,BCL7A,CFLAR,CAMK2B,MAGI1,CACNA2D2,STOML1,TCEAL2,CPS1,RIMS3,CTIF,C2CD2L,SMG7,TRAPPC9,EN2,ACSL4,DLC1,FGF13,BAIAP2,FHL1,PDLIM5,GPR153,SRCAP,TXNL4A,GNAS,GNG4,GRM1,ATXN2L,ICA1,KHK,KIT,MAP4,MMP16,NPR2,PRKAR1B,MAPK7,CCDC25,EMID1,RPH3A,BTBD7,SNCA,AJAP1,TBL1X,WSCD1,TRPC1,HIRA,FLRT2,MICAL1,KCNK12,SLC17A7" Drug 4747_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADORA1,SYT13,CDC42BPA,MARK4,BACH1,SCAPER,GYG2,LDLRAD4,CHM,CHRNB2,CNN3,CSF1,ARHGEF10,RIMS3,SPOCK2,SRGAP3,TMCC2,HEYL,PTK2B,DLC1,TBR1,OGA,SRCAP,CYP46A1,GPR75,GNG3,GSN,AP4S1,HPSE2,ICA1,KCND3,KCNJ3,KIT,LAMA2,MAPT,MOBP,NCAM1,NEUROD1,NOVA2,NTRK3,PAH,CDK18,PDZRN4,PKN2,PTHLH,KHDRBS2,PPP1R9A,CNKSR2,BCAN,MAPK8IP3,MLC1,TTPA,VSNL1,XRCC4,ITM2C,NUP214,JPH3" Drug 4724_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "RALGAPA1,ABHD6,ACTN1,AP2A2,NME5,ALCAM,AMPD3,SEMA7A,PLA2G4C,CDK13,ASPH,CFLAR,CFAP410,HIP1R,CACNA2D2,ASIC3,TAOK2,STOML1,QKI,GREB1,PARD6A,EXOG,GNE,SIDT2,IRAK4,ING4,ELAVL3,FGFR1,CAMSAP1,IQCG,OGA,GALC,GNAS,TDRKH,GRB10,CACFD1,TJAP1,KCNH2,KCNMA1,KCNN2,AFF1,GON4L,TMEM231,RBBP6,GSTCD,TCP11L1,SMARCD3,LIMCH1,ZC3H13,PHLDB1,JMJD6,PLCB1,SLC19A3,PCDHA6,AHCYL2,CHST8,WNK1" Drug 4100_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ASIC1,MTUS1,BIN1,CDC42BPA,APC,PPFIA3,ASTN1,ATM,ATP1A3,CACNA1I,MYRF,BAIAP3,PLEKHB1,LHX2,HOMER3,ENTPD4,SLITRK5,BRINP1,MFAP3L,SMG7,ATN1,ST8SIA3,CELSR3,SUGP2,EIF4G2,LRRC23,MTSS1L,DLC1,FGFR1,ZNF44,GLI2,GNAL,GPER1,MYT1,NPR2,EPN1,PLXNB1,MBOAT7,RALGDS,ARHGEF10L,SELL,MRAS,SLC4A3,SLN,KDM4C,DIP2A,ACSBG1,EXOC7,KIAA0930,DNAH7,TK2,TRIO,ZMYND8,ZIC3,PRDM2,NT5M,STMN4" Drug 5765_DN Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "APOC1,APP,SEMA4G,ALDH7A1,SYNJ2,LRRFIP1,NMT2,AKAP7,NCOR1,CSF1,CSF1R,PDE4DIP,SLITRK5,GIT2,SMG7,TMCC2,TOM1,EDNRA,SIDT2,SORBS3,MRNIP,SPEG,DENND2A,GLUL,GPM6B,SHISAL1,TJAP1,MT1M,ZNF862,NF1,NUMA1,OGG1,CLDN11,PC,PCDH9,MAPK7,SNRK,PTPRN2,RALGDS,ATG16L1,IL17RB,ZNF821,AMBRA1,ZHX3,KDM4C,THSD1,COBL,ATP11A,EXOC7,KIAA0930,CRTC1,GPR161,LMF1,WNT7A,ZBTB14,WNK1,NT5M" Drug 7409_UP Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ABHD6,NDRG2,C1QTNF3,EPB41L5,DNAH17,SCAPER,CACNG1,KYAT1,NEURL1,SLIT2,LY86,ENTPD4,SH2B1,DZIP3,HDAC4,GIT2,C2CD2L,EXOG,DMPK,PHF20L1,MBNL2,VPS13B,ERCC2,EZH1,F8,FGFR1,SRCAP,GRB10,GRIK5,RNFT2,ATXN2L,INPP1,MATK,MBD1,MIA2,PLCD1,MBOAT7,MAPK8,PTN,RIPOR1,RAB3IL1,RGS3,MYH14,SLC1A7,EPN2,SLN,COA1,VAMP1,PLCB1,DMXL2,WDR7,CHST8,CHST5,VIPR2,ZBTB14,SCG2,MVB12B" Drug 5109_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADORA1,AGT,TRMT9B,APC,GAS7,NRP2,HAP1,VAX2,AKAP5,EDRF1,SEC14L5,MFAP3L,RUSC2,DMD,DTNA,ST8SIA3,MRNIP,FGFR1,AGAP2,SORBS1,ERGIC3,GLS,GNAO1,GNG3,TDRKH,SYNPO,IGFBP1,KCNJ3,PACRG,ADAM22,MX1,NF1,NNAT,PPP5C,PROX1,C1orf54,ENOX1,RGR,RGS4,KCTD17,PNMA8A,ASAP3,CNKSR2,SLC2A5,ARHGEF40,ZNF334,DOK5,TROVE2,MAPK8IP3,MLC1,TAL1,PCDHA5,TLR4,TNS1,SPHK2,PRDM2,PARP11" Drug 3204_UP Practolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADRA1B,NME5,ALK,GAS7,AQP4,N4BP2L1,CA4,KYAT1,MTMR7,CBFA2T2,ARHGEF2,DNAJB5,ABI3BP,MICAL2,GREB1,DCAF8,PHYHIP,CTIF,DYRK1A,EGFR,AASS,REEP2,ZNF589,FHL1,PRELID3A,KLF12,ICA1,IGF1,ITIH2,KCNMA1,MAN2A2,ADAM22,NEUROD1,NOVA2,KCNK10,EPN1,PPARA,PPP1R1A,MASP1,PTHLH,ZSCAN2,SUGCT,TCP11L1,RPS6KA2,SCN8A,ASAP3,SLC22A4,SLN,SAMSN1,ACSBG1,TACR1,OBSL1,TMOD1,TRPC1,UBE3A,XRCC4,SLC30A3" Drug 2534_DN Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ADORA3,AMH,SLC4A4,ATP2A2,MTMR3,CACNA1I,LDLRAD4,NEURL1,KCNAB3,CDH10,PICK1,ARHGEF10,VCAN,ARHGEF4,DAPK3,SPOCK3,ABI2,EIF4G2,SORBS3,PIPOX,CAMKK2,ZNF44,SEPT9,ALDH1L1,CRCP,TJAP1,KHK,MAP4,MAPT,MGAT3,NF1,NINJ2,OPRL1,PDE4B,CDK14,PLCD1,MAPK8,RAD52,KHDRBS2,ARHGEF10L,GALNT10,FRMPD1,CCDC92,SLC1A7,SLC11A1,SLC15A2,SNCA,DDN,JMJD6,KAZN,TNS2,THRA,PARD3,FLRT2,XRCC4,MKRN3,EVI5" Drug 6027_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "NR0B1,MRTFA,BEGAIN,BIN1,APLP1,ATP2B2,KALRN,INA,TAOK2,TPP1,WHRN,AKAP5,MYRIP,CTIF,ATN1,DTNB,EGFR,ING4,EPHB1,ZNF589,FYB1,ATP8A2,GFER,GLI2,GNAS,GRIA4,GRM7,GRM8,KLF12,KCNB1,KCNJ5,KCNN1,AFDN,NOVA2,NTRK2,OPCML,CAMKV,SPATA6,PPP5C,GRAMD1C,RGS4,PNMA8A,PRR5L,SYNDIG1,PKNOX2,SLC11A1,INKA2,SYT11,HIF3A,TLR4,TPM1,PRMT8,CA14,FAM155A,FLRT2,MICAL1,CLIP2" Drug 1642_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ABHD6,AK2,BEGAIN,CDC42BPA,ARHGDIG,MARK4,SLC4A4,SCAPER,BAIAP3,LDLRAD4,HAP1,SLIT2,EPS15L1,FADS2,SULT4A1,HOMER3,EDRF1,LYPD1,DMPK,DSCAM,RCAN1,DTNA,HIPK3,CNNM1,MBNL2,LRRC23,FHL1,FOXG1,C1orf61,GCNT2,MSL3,HSF2,IRF8,VWA5A,MIA2,CD200,NDUFA5,NRGN,LRP12,PPP2R5C,MAPK8,WDR25,PEX5,TCP11L1,EMID1,FOXRED2,FNDC3A,ZCCHC24,KDM4C,INKA2,STX1A,ROBO3,ZNF34,TRPC1,WIPF1,HPS4,KCNAB1" Drug 7208_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ALCAM,BBOX1,MRTFA,BEGAIN,AMPH,ARRB1,CADM3,KSR1,ST3GAL5,SCAPER,BAIAP3,CAMK2G,NEURL1,SEPT7,CHN2,ZFYVE9,AKAP7,CRY2,GIT2,ARMCX2,DLC1,FER,BAIAP2,SORBS1,OGA,GCNT2,GLS,TDRKH,KLF12,IL11RA,JAK2,KCNMA1,KCNQ3,MAPT,MSI1,NPR2,RETREG1,PRODH,PTPRE,RAD52,C1orf54,RASGRF1,ZFHX4,ITSN1,SLC1A3,SLC6A9,SNCA,ZCCHC24,KDM4C,PHLDB1,PLCB1,TRIM2,PIK3R5,XRCC4,PLSCR4,ST7,PHTF2" Drug 4965_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "TRMT9B,BIN1,FAM131A,RASL11B,ALDH7A1,CADM3,KIF1A,CDK5R1,CACNA1I,CACNA1G,BAIAP3,ARHGEF1,ARHGAP33,CACNA2D2,FADS2,HOMER3,ARMC8,CSF1,CSF1R,GREB1,CTIF,EN2,PIPOX,KIAA1109,FHL1,SEMA4D,GPR153,GAP43,SRCAP,USP19,GSN,KCNJ3,KCNQ3,KIF5A,ADAM22,RETREG1,MAPK10,PRPH,FAM120C,ZSCAN2,ZNF493,RGS12,DOCK10,RPH3A,SLC15A2,KIF13A,ZC3H13,ZBTB43,ATP10B,ELOVL4,PHLDB1,TBCEL,PARD3,TRIO,KCNK12,AP3B2,SENP7" Drug 6638_DN beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ASIC1,BIN1,AMT,APBB2,CDK13,DNAH17,ALDH4A1,ATM,SLC4A4,SCARB1,CLCN4,PICK1,WHRN,DZIP3,DNAJC6,DMPK,FAM13A,AASS,EN2,TUBD1,COQ7,ZNF549,ETV1,ZNF589,FGFR1,POLL,GPER1,KHK,KPNA5,MDM4,CNOT4,PAK3,PIK3R1,PMS2,GRAMD1C,SNRK,PID1,BEND5,SEC61A2,MYH14,ASAP3,ANKRD6,SMARCD3,EMC1,IQSEC2,DDN,SS18,ARHGEF12,CRTC1,BEX4,PARD3,SSBP2,ZKSCAN5,UBTF,NT5M,SMIM8,PHTF2" Drug 4645_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ACLY,ADCY6,BIN1,CDK10,CDK13,CHM,B4GALT6,HOMER3,AKAP7,SLC4A7,PDE4DIP,SDC3,USP6NL,TBC1D5,GIT2,DBT,KIAA0753,PARD6A,DLG3,FEM1B,FAM13A,MBNL2,EN2,ANKMY1,RRAGB,FGFR1,IQCG,ANKFY1,TRMO,DENND2A,ERAP1,ZNF276,DHX35,SHISAL1,NDP,NFYA,CNOT4,PAK3,PLCD1,RC3H2,SAMD9,PTK2,PTPRN2,GTDC1,CLIP1,ASAP3,URGCP,FAM214B,TMCC1,EMC1,SS18,NCDN,TCF4,GPR161,WIPF1,KLC2,EVI5" Drug 4415_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "ASIC1,NDRG2,ADCY6,APAF1,CDC14B,ARHGDIG,RASL11B,ATP2B3,HAP1,CD86,CACNA2D2,CLCN4,RGS6,FAM13A,MBNL2,ELN,LRRC17,FGFR1,CAMSAP1,FHL1,PDLIM5,NSG1,TBR1,FYB1,GNG3,SYNPO,IL11RA,IL12A,KCNJ5,KCNMA1,ADAM22,NPPA,OMG,SNTG1,GPR85,PFKFB2,CDK14,PLCB2,MTRF1L,PLXNB1,PTPRB,CCDC40,RORB,RTN1,SEMA6D,SH3BP2,SH3GL3,DOCK10,SLC11A1,ATP10B,AJAP1,SYNE1,DOCK9,TNS1,ZNF154,SLC17A6,MVB12B" Drug 4479_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.56E-06 7.62E-02 3.67E-05 4.18E-04 57 196 "NDRG2,ADORA1,APAF1,GAS7,AQP6,BAIAP3,CACNG1,RUNX1T1,SLC24A2,NCOR2,MICAL2,DTNA,SEMA3D,EGFR,PLXNC1,NCALD,F5,FOXG1,C1orf61,AFF2,CSDC2,RND1,GNAO1,GRM8,HTR2A,KCNB1,KCNF1,KCNN1,SMAD1,MAN2A2,MSR1,NEUROD2,NF1,NTRK2,NUCB1,PDE4B,PDE4D,PLCB2,POU6F1,RET,KCTD17,MYH14,RPS20,KANSL3,PKNOX2,SLC11A1,TSNAXIP1,ARHGAP26,SYT11,MCF2L,SMG6,TK2,ICAM5,TNS1,OSBP2,KCNAB1,MVB12B" Drug CID000004253 morphine hydrochloride Stitch 1.58E-06 7.73E-02 3.72E-05 4.24E-04 115 481 "ABAT,ACLY,TKTL1,ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,AP1B1,RGS20,ARRB2,RGS9,CA4,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CALB1,CALM1,CCK,CCKBR,LRBA,ZBED1,CHRM1,SULT4A1,CNR1,RGS6,CX3CR1,DBI,B3GAT3,GSDME,NTM,WDR20,DLG4,DRD1,EDN1,RGS17,DMTN,FOXM1,CSPG5,B3GAT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,CHL1,GABRB1,GABRB3,GABRG1,GABRG2,MSTN,GFAP,GFRA1,POLL,PRLHR,GRIA1,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HAS2,HRH3,TNFAIP8L3,HMGCR,IGF1,IL12A,KCNA1,KCNA6,KCNH1,KCNJ3,L1CAM,NCAM1,NCAM2,NEFM,NEFH,NODAL,OPRL1,PAH,PDYN,PENK,ABCB1,PRKACB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RGS7,SAFB,MAPK12,ASRGL1,SLC1A2,SOX10,SST,SYN1,SYN2,TAC1,TACR1,LEFTY2,TGFBR3,TRH,UBC,PORCN,SLC17A7,CAMK1G" Drug CID000004737 pentobarbital Stitch 1.60E-06 7.82E-02 3.76E-05 4.28E-04 63 224 "ASIC1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,ARHGDIG,ALDH7A1,CACNA2D1,CBS,ASIC3,CHRNA4,CHRNB2,APPL1,AASDH,EDN1,EDN3,FCF1,STX2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIN2C,GRIN2D,GRM3,KCNH1,KCNH2,BCO1,NOS1,NPY,NPPA,OPRL1,POU6F1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,SST,MLC1,TAC1,TRH,PDIA2" Drug CID000129695 Naspm Stitch 1.65E-06 8.07E-02 3.88E-05 4.42E-04 10 13 "DLG4,B3GAT1,GRIA1,GRIA2,GRIA4,GRIK1,GRM3,NASP,SYP,TACR1" Drug CID000000951 noradrealine Stitch 1.68E-06 8.25E-02 3.97E-05 4.51E-04 133 575 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,API5,ASCL1,ATP1A2,ATP1A3,SLC4A4,ALDH7A1,CACNA1I,CACNA1G,BSN,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,P2RX6,CBFA2T2,LRBA,CACNA2D2,CHGA,CHGB,CHRM1,CHRNA4,CHRNB2,SULT4A1,COX4I1,CREM,PLCXD3,DMPK,DRD1,EDN1,EDN3,EDNRA,EDNRB,CACNG7,TUBD1,HSPA12B,CACNG2,TUBB4A,OLFM1,ACTL6B,GAP43,TUBA8,MSTN,LOXL3,LPAR4,PLCD4,GRIN1,MAP4K5,HRH3,ATXN2L,TNFAIP8L3,HMGCR,HTR2A,HTR5A,IGFBP1,TUBB2B,MAOB,MMP16,MMP17,P2RY13,NDP,NODAL,NOS1,NPY,NPPA,NUCB1,OPRL1,P2RX7,P2RY1,PAH,PDYN,PENK,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,PLCD1,PPARA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,KLK6,PYGM,QDPR,RGS3,RYR1,RYR3,MAPK12,HSPA4L,SHANK2,SNAP25,SST,ABCC8,PLCB1,SYT1,TAC1,TACR1,LEFTY2,ACTR6,PIK3R5,TRH,TUBB2A,TUBB1,UBTF,P2RY12,PORCN,ZNF24" Drug ctd:D001464 Barium CTD 1.71E-06 8.39E-02 4.03E-05 4.59E-04 28 72 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB4,CHRNA4,CHRNB2,SGK2,CACNG3,CACNG2,GNG3,KCNH1,KCNJ3,KCNJ4,KCNJ10,KCNK1,P2RX7,GNG2,PTK2,SGK1,SLC8A1,SLC12A4,PLCB1,TRPC3,SGK3" Drug 6028_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "NME5,AMPD3,AMPH,BIN1,BRINP2,N4BP2L1,ADAM23,CBARP,CHI3L2,MYEF2,ELMO1,GSDME,TRAPPC9,MBNL2,RASGRP2,ST3GAL6,NEU3,GCNT2,GFER,PCDH17,ATF7,GPR22,GSN,ATXN2L,HLF,TJAP1,KCNC1,KCNJ4,MAOB,MDFI,MOBP,ADAM22,NCAM1,NINJ2,CDK18,CAMKV,MINDY2,MAPK7,RELN,FAT4,ZMAT4,KCNIP1,SELL,SLC1A2,SLC1A7,SLC11A1,SNAP25,EMC1,UNC5B,SPTB,COLGALT2,POPDC3,SEMA4A,DOCK9,MICAL1,SLC30A3" Drug 5729_UP Disulfiram [97-77-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "SEMA7A,APC,PRX,BMP7,CAMK2B,TMEM257,CLU,PHF14,DCT,C2CD2L,HS3ST2,ELAVL3,LRRC23,RASGRP2,CDKL3,BAIAP2,FLT1,GABRA2,DENND2A,SRCAP,RND1,ELOVL5,ITIH2,KCNMA1,KIT,MMP16,MOBP,MT1M,PCSK1,PDE4D,PIK3R1,EPN1,PTN,C1orf54,TMEM206,RASA3,HSPA4L,CPEB3,SLC1A7,TSPYL2,INKA2,ARC,COBL,SYT5,TAC3,SYNE1,SLC44A1,BEX4,TRH,VSNL1,PRDM2,NAV3,SLC17A7,KCNAB1,MVB12B,NUP214" Drug 3179_UP Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "FZD9,ALCAM,ANK1,APAF1,RGS20,ATP2B2,CA4,P2RX6,ARHGEF2,CDC42,DCLK1,RCBTB2,TAOK2,TMEM59L,CREB5,RGS6,MICAL2,PHF14,RIPOR2,TMCC2,DTNA,HIPK3,ING4,ETV1,HPCAL4,DLL3,SESN1,JAK2,KCNJ4,KCNMA1,KPNA5,CD200,PCBP3,NTRK2,CLDN11,PDE3B,PLTP,SDK2,PILRA,RGS12,PBRM1,TCP11L1,LRRTM4,PPP1R9A,CPEB3,LIMS2,FAM214B,TTBK2,RGL1,PLCB1,ARHGEF12,SPX,ZMAT3,SEZ6L,WIPF1,XRCC4" Drug 3858_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "ABHD6,NDRG2,APLP1,SEMA4G,CDK13,STX16,ADAM23,CFLAR,LDB2,USP2,SCARB1,ADGRG1,CRY2,SNCAIP,DAPK3,CTIF,BRINP1,SV2A,RABGAP1L,EDN1,EFNB3,ELAVL3,TNK2,C3orf18,ERCC2,SRCAP,C1QL1,GLYR1,HTATSF1,GPER1,GSN,IL6ST,ITGAM,JAK2,KHK,LSS,SMAD1,MEF2C,KITLG,MMP16,MOBP,ADAM22,NEK1,PDE3B,TMOD2,SAMD9,RASA3,ST6GAL1,PPP4R3A,ARHGEF40,SOX2,CDK19,FLRT2,VAV2,CLIP2,ZBTB38" Drug 6044_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "ABHD6,ALCAM,NCOA1,CFLAR,CBFA2T2,SEPT7,FOXN3,SLIT2,NMT2,ARMC8,RCHY1,AKAP12,CSF1R,FAM169A,RASSF2,JAKMIP2,DLG3,DTNA,HIPK3,EML1,COQ7,DMTN,TAOK3,FGFR3,SYNCRIP,DPYSL4,STAU2,SRCAP,GLYR1,TDRKH,GRB10,GRIK5,NR3C1,INPP1,MPP2,NUMA1,RETREG1,RAB3IL1,SBF1,ZNF821,SH3BP2,ITSN1,PPP1R9A,TTC17,CLASP2,PHLDB1,VAMP1,PLCB1,TACC1,TMEM121,ZNF34,TK2,BEX4,PARD3,ZIC1,MVB12B" Drug 3114_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "CDC42BPA,MYOM1,PROM1,BMP7,SGCE,REPS2,CHN2,LHX2,RAB26,CREM,FEZ1,SLITRK5,RIMS3,DNAJC6,DTNB,CELSR3,ETV1,FGFR1,GPR153,GABRA4,ZMYND11,GATM,ADAM28,RUNDC3A,GNG3,DIPK1A,KIF5C,MAP4,SCAMP5,NCAM1,NOVA1,NRCAM,PCDH9,PLCL1,PMP22,CEP41,PTPRB,PTPRN2,TMEM255A,GAL3ST4,PRR5L,WLS,SATB1,SLC1A3,PALLD,TNIK,SPTB,INKA2,TBCEL,TRIM2,TNNT1,TRPS1,FLRT2,TRIM9,SLC17A7,KCNAB1" Drug 4311_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.73E-06 8.47E-02 4.06E-05 4.62E-04 56 192 "NME5,CDK10,ASPH,MAP7,SRSF11,HOMER3,FCF1,SIDT2,IRAK4,ING4,BAIAP2,DENND2A,HBS1L,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,KLF12,HNMT,AGFG1,IL6ST,KHK,MAP4,MEF2C,NFIX,NUMA1,STRN3,RC3H2,PKN2,PID1,PLEKHB2,ATG16L1,GSTCD,KIRREL1,CSRNP3,PPP1R9A,ASAP3,CCDC88A,KDM4B,TBCEL,TBL1X,EHBP1,PSD3,DICER1,TMPO,PARD3,SSBP2,SF1,ZBTB38,WNK1,PRDM2,HPS4,KCNAB1,KAT6A,FXR1" Drug ctd:C041786 palm oil CTD 1.75E-06 8.56E-02 4.10E-05 4.66E-04 344 1742 "SERPINA3,ABAT,ACADM,ACLY,ABHD6,ACTN2,SLC25A25,TMCC3,FZD9,AP2A1,MTUS1,PCDH19,SORCS2,AK2,PLA2G6,ALAD,SPARCL1,C1QTNF4,SRPX,ARHGAP20,LTBP4,AMPD3,MAP4K3,GPAM,PHYHD1,APOC1,PRX,ARNTL,ARRB2,PLA2G4C,ASPA,ALDH4A1,ATP1A1,ATP2A2,B3GALT2,ATP6V0A1,DOCK11,BCHE,DCAF5,GPR146,PROM1,ARHGEF7,C1QC,RAB29,CA4,RHBDL1,RUNX1T1,KYAT1,FMNL3,CD38,LGI1,CDO1,RCBTB2,MS4A7,CLU,NGEF,FADS2,QKI,LY86,CNN3,AKAP6,LETMD1,COL11A2,MAGED1,BAG4,MFSD4A,HS3ST5,CP,PREPL,CREM,AKAP12,ANKRD44,GDA,CRYM,CSF1R,CSF2RA,CSNK1E,SOCS5,CNTNAP2,CYBB,DOCK4,KATNAL2,ARHGAP24,HDAC4,LONRF1,LIN54,DBI,ARMCX2,SPATA2,HEPH,MED24,RHOBTB1,WDR20,CCDC3,DLG4,OLIG1,DPH1,DRP2,PDCD6IP,ECM2,EDNRB,HIPK3,HEYL,LPAR6,ASB3,EIF4G1,SORBS3,PCOLCE2,BSCL2,ELN,EML1,EMX2,COQ7,EPS8,EXTL1,ADGRV1,GMPR2,NRN1,F3,ABCA8,EFEMP1,FCGR1A,FCGR3A,FCGRT,FGF1,FGFR1,FHL1,POLK,SCARA3,SEC23B,FOLR2,SPECC1,KHDRBS3,DACH2,GPR153,DOT1L,DKK3,GAA,GAB1,GALNT15,IP6K3,HIGD1B,ACSS1,MYOZ2,GATM,ALDH1L1,SESN1,PPARGC1A,DHRS4,DBF4,RAB30,GLUL,RAB40B,GPT2,ADGRA3,GPM6A,TMEM25,GSTT2,BVES,PSIP1,GUCY1B1,WIF1,NCKAP1L,MIER3,HLF,ELOVL5,ACOT7,HMGCR,HNMT,HP,NEGR1,HSPA1L,IRF8,IDH3B,IFI16,MYLK2,ZNF546,IGF1,IGFBP1,IL12A,INPP1,ZNF385B,ITGAM,ITPKB,SLC35G1,KCNB1,KCNJ11,KCNMA1,LIFR,SFXN5,LMO1,FGFBP3,MAG,GPR155,NAT8L,MATN2,MBP,LDLRAD3,TM6SF1,MEST,KITLG,CD200,DBNL,CCDC80,THYN1,MXI1,MYH3,MYH7,MYL3,MYO5A,FXYD6,NBL1,NOS1,NPR2,NUCB2,OCRL,CHAMP1,PC,PDE1A,PDE4B,PENK,CYTL1,PFKFB3,PFKP,ABCB1,DUSP26,SERPINE2,CCSER2,SNX10,FTO,SMOX,PLP1,PLTP,PMP2,PMP22,PSAT1,SCHIP1,PRRX1,FA2H,SH3KBP1,PPP1R1A,CRLS1,PRKAB2,PRODH,RELN,WBP1L,PTHLH,PTH1R,PTPRE,PTPRG,PTX3,RBBP8,RFX4,RGS4,RGS10,ARHGEF10L,RIC8B,ZFHX4,MYH14,ROBO1,RPE,TMEM100,CLIP1,FNIP1,HES6,TNFRSF19,RASA3,HSPA4L,SGK1,KIF21A,CPEB3,SLC1A3,SLC8A3,SLC11A1,SLC12A4,NAPB,MTERF2,EFHD1,SLC22A4,SLN,SNCA,TMCC1,SPP1,ARHGAP26,CDK19,SMOC1,ST5,ADHFE1,SULF2,SEMA4A,DDHD2,CAMTA1,EXOC7,KLHL4,TBX15,ACSL6,TF,THBS4,FBXL16,TIAM1,TMEM9,TJP1,ACTR6,BHLHB9,TLR4,KCTD2,TNNT1,RASD2,TPM1,NPL,TPM4,WBP2,TRPC3,FNDC5,LRTM2,TUBB2A,UBC,CADM1,UCHL1,UGT8,VLDLR,LMF1,KLC2,NPDC1,SLC13A3,ETNPPL,SF1,ZIC1,NDRG4,ZBTB16,SH3GLB2,ZFAND5,INTS3,PMEPA1,GDPD5,LMAN2L,HPS4,SEMA3B,KCNAB1,NELFE,PLSCR4,C12orf4,HRASLS,NETO2" Drug ctd:D014415 Tunicamycin CTD 1.78E-06 8.70E-02 4.17E-05 4.74E-04 315 1577 "DPF1,GPRIN1,CDC7,PTCHD1,BEND6,AP1B1,KLHL13,AGT,OSBPL6,AK2,SRPX,MARCH4,BEGAIN,AMT,ANK2,PPFIA4,APOC2,APP,PDXK,ARRB1,PDE8B,ASGR1,RASL11B,TMEM108,SLC4A4,ATP2A2,ALDH7A1,N4BP2L1,ATP6V1G2,ATP6V0A1,ADAM23,SEC11C,RGS11,BCL2L2,BCS1L,BID,GPR146,CFLAR,CDK5R1,ST3GAL5,GPC2,CACNB2,CALM1,CANX,SLC25A14,CARS,RUNX1T1,PRC1,INA,ARHGEF2,CDC27,CDH2,CDH10,CDO1,CCPG1,CACNA2D2,COPB2,CBARP,CHGA,SLIT2,NMT2,CNN3,CABP1,COL4A5,SLC25A27,LETMD1,CHD1L,FEZ2,VCAN,PPP1R16B,CTH,CFAP61,CTNND2,RIMS3,BRINP1,DBI,DBT,AK5,DLG4,DYNC1I1,NR1D2,DMTF1,DSCAM,E2F5,EBF1,EDIL3,EEF1A2,SIDT2,RBM12,ASB3,EIF5,PCOLCE2,TMEM35A,EIF1,ENO2,COQ7,SEZ6,KCNMB2,NCALD,EFS,CDKL3,ARMCX1,TBC1D16,TUBA1B,TUBB3,TUBB4A,ATP8A1,FDFT1,GORAB,FECH,PRKAG2,ATP5PD,SEC23B,C1orf61,SYNCRIP,FOXM1,FLT1,TMEM175,WDR83,UFM1,CGREF1,DLL3,PHYHIPL,GALC,NEK6,GAP43,MTHFD2,SYT17,GATM,MMADHC,PPARGC1A,GLDC,GLS,ZNF638,OS9,INSM2,LOXL3,GNAS,GNG4,GPT2,PSRC1,GPM6B,TUBA1C,SPACA9,GRM2,KAT7,MFSD2A,FICD,LINGO1,RNFT2,GUCY1A1,SLC2A6,PACSIN2,ACOT7,HMGCL,HMGCR,HMX1,CPT1C,HSPA1L,HSP90AA1,SMAP1,IDH3A,IGF1,DISP2,IL12A,INPP1,INPP5B,ITGAM,KCNJ16,KCNK1,STMN1,SFXN5,LSS,MDM4,MEIS1,MMP17,MRPL42,DBNL,COMMD5,BLOC1S2,TAGLN3,MYCN,HNRNPM,NAP1L2,FXYD6,NCAM2,NDUFA5,RCOR2,NEFH,NFE2L2,NNAT,NME4,DNHD1,NPPA,NPTX2,NRCAM,NUCB1,NUCB2,OGDH,PCDH9,PDE4B,PDE4D,PDGFRA,ENPP2,GPR85,GNG2,PFKFB3,PFKFB4,PFKP,DUSP26,SERPINE2,PIK3R1,SNX10,PKM,KCTD15,GPSM2,SLC25A23,PCDH18,POLR2F,PPARA,MED1,PPP2R2B,PPP2R5E,PPP3CA,PPP3CB,VSTM2L,PKIA,MAPK3,MAPK8,MAPK9,LAMA1,WDR25,PTPRH,QDPR,RAB3IL1,RET,PRRT2,RGS4,NUDT11,TMLHE,CYB561D1,MRAP2,TMEM100,SPIN3,ACER3,RTN1,RMI1,DGLUCY,SARS,HES6,TNFRSF19,SFPQ,PPM1E,CPEB3,SHMT2,SEC31A,CLSTN1,SLC1A3,SLC6A9,YPEL4,SLC8A1,ABTB1,SMARCA4,RCOR3,SNAP25,FAIM2,GLT8D1,ZNF423,BEX1,LMO3,ZNF621,ERBIN,MPRIP,STAC2,SYPL1,ANKRD12,FBXW11,TCF4,PCDHB9,PCDHB3,AKNA,AHCYL2,VWCE,DICER1,ZMAT3,ZNF34,ZNF106,CDH22,HEY1,TMOD1,PDSS1,ZMYND8,CADM1,DNAJC12,PDIA2,VGF,VIPR2,BEST1,TBC1D15,KCNK12,KCNT2,POLR3H,ZNF195,LAMP5,CA10,LRP8,STOX2,LMAN2L,TUBA1A,ADAMTS9,CAMK1G,NETO2,CBLN2,SOCS4,ST8SIA2" Drug 5215_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-06 8.84E-02 4.23E-05 4.81E-04 52 174 "OSBPL1A,NME5,BIN1,APP,MARK4,ST3GAL5,CA4,HIP1R,CLGN,CHM,CLU,DNAJB5,CRY2,PDE4DIP,SDC3,CTH,EDRF1,RCAN1,DNAJB6,ABCC5,MBNL2,SEMA4D,SORBS1,SRCAP,GLYR1,DIDO1,NR3C1,HMGCR,HSF2,ICA1,ZNF862,NAP1L2,NF1,OXTR,PLCD1,MBOAT7,KLK6,MORC4,ATXN1,HSPA4L,SGK1,SH3BGR,PPM1E,DOCK10,KIF1B,SEMA4A,ZEB1,TRIM2,VLDLR,LAT2,ZFP37,FXR1" Drug 337_UP felodipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASIC1,BRAP,ALK,BIN1,APBB1,ARNTL,BMPR1B,CACNA1A,CACNA1E,SCARB1,LHX2,SMARCAL1,CHD5,EDNRB,EFNA3,LRRC23,EPHB1,STX2,BAIAP2,TRMO,CAMKK2,TBR1,FYB1,ERAP1,COPS8,GNAL,LILRA2,GRK4,RASSF8,ATXN2L,HTR2A,ITPKB,KCNMA1,L1CAM,SLC11A2,NRGN,SETD4,P2RX7,MASP1,PYGM,KCTD17,TTLL7,SH3GL3,ZNF365,SLC15A2,CAND2,LHPP,AJAP1,TACR1,KAZN,TBL1X,DOCK9,TF,PARD3,PLPPR2,WIPF1,ZNF23" Drug 2244_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ARID1A,NDRG2,SEMA6A,APC,APP,CDK10,SEMA4G,MARK4,CFLAR,GYG2,HAP1,ARHGEF2,ARHGAP33,SLIT2,PICK1,CRY2,CSF1,DZIP3,RIMS2,TBC1D5,DAPK3,CTIF,DSCAM,EGFR,SORBS3,RRAGB,KAT8,FGFR1,FAM49B,PRELID3A,GPR153,INPP5K,MALT1,RAB30,GLS,GNG4,SPACA9,GSTM5,IL6ST,MAP4,NF1,NOS1,PTHLH,PEX5,RGS12,FBXW7,ZNF821,SUPT20H,PPP4R3A,WDTC1,ZCCHC24,PLCB1,PSD3,TK2,TRPC1,MICAL1,SSPN" Drug 4572_UP Cyanocobalamin [68-19-9]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "SLC12A5,ADRA1D,AGT,PLA2G6,PTCH2,ATP2B2,SLC2A11,SYNJ2,CFAP410,STOML1,ABCG2,CNTFR,MYRIP,CREM,NCOR2,RGS6,CNTNAP2,CTNND2,RIMS2,DAPK3,CTIF,BRINP1,MFAP3L,AK5,RABGAP1L,DRD1,DTNA,ABCC9,ELN,MTSS1L,NSG1,GAB1,ZNF44,ERAP1,SIGLEC8,GPD2,PRUNE2,TPPP,GRM8,ITIH2,KHK,TAGLN3,NPTX1,PDE2A,PFKFB2,LRRN3,KHDRBS2,RGS10,FRMPD1,HECW1,MAPK8IP3,ASTN2,TAL1,TK2,SEMA3B,FAM13C,GAN" Drug 2819_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "NDRG2,AMT,PPFIA3,N4BP2L1,SCAPER,CACNA1I,BAIAP3,CA4,CAMK2G,SLC16A4,NECTIN3,CNTNAP2,CTIF,HS3ST2,EFNB3,SORBS3,HSD17B14,DMTN,STX2,KIAA1109,FGF12,FHL1,FYB1,HBS1L,RND1,GPER1,KCNK2,KCNMA1,MMP16,NEUROD1,NF1,LRRN3,MAPK8,RELN,PTCH1,RAB3IL1,ZMAT4,RGS3,TCP11L1,ASIC4,MRAS,NLGN1,SLC1A7,SMTN,PKNOX2,ARHGEF40,SLCO1A2,ABCC8,POPDC3,SEMA4A,PCDHA5,CABIN1,VIPR2,ZNF45,PRDM2,SEMA3B,SSPN" Drug 3207_DN Debrisoquin sulfate [581-88-4]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ALCAM,AMT,FAM131A,APOC1,BCAS1,PPFIA3,RGS20,MARK4,ATM,BTRC,CAMK2G,SCARB1,SOCS6,B4GALT6,ZFYVE9,FADS2,QKI,SOCS5,HDAC4,MFAP3L,SMG7,CDON,TOM1,HSD17B14,COQ7,FHL1,SEPT9,SRCAP,POLL,NR3C1,ELOVL5,HNMT,IL6ST,MAP4,MBD1,ADAM22,NUMA1,PDE4A,MINDY2,MAPK7,CNNM2,RAD52,RGS12,FBXW7,EMID1,FOXRED2,ZNF365,SMARCD3,WDTC1,ZCCHC24,KDM4C,TROVE2,CABIN1,ZMYND8,HIRA,VGF,VIPR2" Drug 4639_UP Felbinac [5728-52-9]; Up 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASPHD1,ALK,KCNAB2,PPP4R4,KRIT1,PICK1,FAM149A,GAL3ST1,ARHGEF10,PHF14,CTNND2,FAM131B,CTIF,CNIH3,HS3ST2,ABCC9,SGK2,CNNM1,EFS,EZH1,SORBS1,FYB1,SIGLEC8,GPR75,GNAL,GPM6A,GPM6B,STON1,HTR2A,ITIH2,ITPKA,MATN3,AFDN,TNPO2,RAB3A,KCTD17,TCP11L1,FAM102A,NLGN1,LIMCH1,ZHX3,ARHGAP26,NFASC,TROVE2,ARC,COBL,SYT5,WSCD1,TMOD1,SSBP2,TUBB1,VGF,VLDLR,WIPF1,KCNK12,SLC17A7,DPF3" Drug 5616_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "DPF1,ASCL1,RASL11B,CD86,KCNAB3,TAOK2,CNTFR,COL9A3,CSF1,GREB1,NOS1AP,RIPOR2,ARHGAP24,SPOCK3,EDNRA,SGK2,MTSS1L,SPEG,EXTL1,C1orf61,GFAP,LYVE1,GNAO1,PRUNE2,PCLO,GRIA1,ADAMTS8,GRIN2C,GRM1,HPSE2,IL11RA,KIF5A,MAG,MAN2A2,MOBP,ADAM22,PCDH9,GPR85,NECAB2,MAPK8,PTAFR,PTPRB,RYR1,ZNF821,SH3GL3,CNKSR2,RPH3A,NMNAT2,CDK19,NPAS3,MLC1,SYN2,POPDC3,MICAL1,SLC30A3,KCNAB1,MVB12B" Drug 4003_DN Tolazamide [1156-19-0]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "TRMT9B,APC,GAS7,ALDH4A1,KIF1A,MYRF,ARHGEF1,CHI3L2,LHX2,CLU,DNAJB5,CREM,SH2B1,TENM4,ARHGEF10,EDRF1,AASS,MTSS1L,STX2,EZH1,AFF2,CINP,GAD1,GFER,MSL3,POLL,GPM6B,TDRKH,GPER1,SHISAL1,MN1,CNOT4,NOVA1,OPCML,EPN1,PPP5C,WDR25,ENOX1,RPS6KA2,FRMPD1,FBXO11,SLC6A9,SNCA,TSNAXIP1,MAPK8IP3,ARHGEF9,ADGRL3,KIAA1107,KIAA0930,TRIM2,THRA,TK2,AMACR,XRCC4,REEP1,EMSY,NT5M" Drug 3935_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "NDRG2,APC,APLP1,APP,STX16,GYG2,SLC16A4,CBFA2T2,FOXN3,CNTFR,RCHY1,CPS1,DTNA,FCF1,VPS13B,F3,ZNF589,KIAA1109,PRKAG2,C1orf61,CSPG5,GAD2,RAB30,GRIK5,GSN,IL6ST,KCNH2,KCNJ3,MDM4,MPP2,ADAM22,ZNF862,NPTX1,PFKFB2,MINDY2,PPP5C,MAPK8,PTHLH,PEX5,LIMCH1,WDTC1,SOX2,EMC1,IQSEC2,THSD1,RGL1,AJAP1,PLCB1,WASHC4,PARD3,TRPC1,VIPR2,WIPF1,ZIC3,ZNF24,PHTF2,SENP7" Drug 6012_DN Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "SLC12A5,AMH,APBA2,APLP1,EIF4G3,SLC2A11,ALDH7A1,ADAM23,LDLRAD4,PLEKHB1,HOMER3,BAG4,AKAP12,MICAL2,CNTNAP2,RABGAP1L,CDON,DRD1,ATN1,DSCAM,SORBS3,STX2,DENND4A,ANKMY1,FAM49B,GABRA2,MSL3,POLL,TDRKH,KCNJ3,MAP4,TM6SF1,MMP16,MPP2,LRP12,POLG,MINDY2,GON4L,PTN,CEP97,MRAS,ASAP3,CXXC4,SNCA,ZHX3,TTBK2,PLCB1,MCF2L,EXOC7,IQCE,CRTC1,PCDHA6,RIMBP2,VAV2,VLDLR,LMF1,GDPD5" Drug 3685_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADRA1D,FAM135A,PDE8B,N4BP2L1,ADGRB2,NEURL1,IFFO1,AATK,CSF1,IPCEF1,PDE4DIP,RIMS3,NTM,ARNT2,SHANK1,EDN1,ATP8A1,FLT1,NSG1,ALDH1L1,CSDC2,GNAL,GPM6A,GPM6B,GPER1,GRIN1,KLF12,IGSF1,MMP16,ADAM22,NPTX2,PCBP3,PDE4D,PTCH1,ZSCAN32,PTPRO,RGS4,S100B,SLC1A6,SLCO1A2,SCN3B,ZC3H13,ATP10B,ARC,SYT1,KAZN,MCF2L,TAL1,ZEB1,TNS1,PDIA2,ETNPPL,ZIC3,SPHK2,SEMA3B,KCNAB1,KAT6A" Drug 4391_UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASIC1,ACTN2,PLA2G6,APAF1,AZGP1,CFAP410,HIP1R,TAOK2,TPP1,CSF1,IPCEF1,VCAN,DCAF4,NOS1AP,RIPOR2,ARHGAP24,MYEF2,EDN1,EFNA2,ELAVL4,EPB41,SPEG,TUBB4A,DCTN2,GAD1,GAD2,GRIK1,GRIK5,GRM2,WIF1,ITGA7,KCND3,KCNH1,MAOB,MATN3,MYO7A,NHLH1,NPY,NPPA,OPRL1,CLDN11,GPR85,PILRA,RGS12,KANSL3,SLC6A9,OGDHL,SORCS3,SNAP25,SNCA,SOX2,MLC1,CUX2,FAM189A1,SLC30A3,ADAMTS9,ITM2C" Drug 5049_UP Indomethacin [53-86-1]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASIC1,NDRG2,AMH,PPFIA4,CDK10,ARHGDIG,CACNA1G,CACNA1A,KALRN,GPR37L1,CHGA,CHI3L2,TAOK2,ZFYVE9,TMEM59L,BRINP1,MFAP3L,DUSP9,RASGRP2,MTSS1L,ST3GAL6,FGF1,FGFR1,GLI2,GNAO1,CACFD1,HLF,HPSE2,ITIH2,KCNN1,NEUROD1,PDGFRA,POU3F2,CNNM2,RAD52,RGS12,ZFP2,IL17RB,DOCK10,SLA,SLC8A1,SNCA,SOX10,DOK5,SPTB,ZBTB43,DDN,ATP10B,PHLDB1,KLHL4,PCDHA5,TLR4,PIK3R5,TRPC3,VGF,NT5M,MVB12B" Drug 4979_UP Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "SYN3,ASIC1,NME5,SPARCL1,APOC1,SYNJ2,GYG2,SGCE,CACNB2,ARHGAP33,DGKG,CTIF,MFAP3L,EXOG,SGK2,SIDT2,EFNB3,ELAVL2,ELAVL3,TUBB4A,KHDRBS3,TBR1,GAD1,GAD2,SRCAP,LYVE1,RND1,GPM6B,GPER1,HLF,ITIH2,KCNH2,LAMA2,MX1,NF1,P2RY1,KCNK10,RETREG1,PRKCB,SAMD9,SEMA6D,SLC1A2,RPH3A,SLC1A7,LIMS2,SNCA,KIF13A,WDTC1,AJAP1,PLCB1,ASTN2,POPDC3,WSCD1,SIN3B,HIF3A,MVB12B,NUP214" Drug 2533_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "APAF1,APP,CDC14B,PPP4R4,ATP6V0A1,FGF17,SYNJ1,MYRF,LDLRAD4,MAP7,CBFA2T2,CDO1,B4GALT6,EPS15L1,CRY2,DZIP3,PHYHIP,SPOCK2,SGK2,HIPK3,CNNM1,EFNB3,EIF1,HSD17B14,EN2,ERBB2,CEND1,KIAA1109,OLFM1,BAIAP2,FHL1,PDLIM5,KHDRBS3,GAD2,SIGLEC8,GNAO1,RASSF8,PTGDR2,NCKAP1L,KLF12,NRCAM,CCSER2,STRN3,CARF,UEVLD,SLC1A3,PEX26,DOK5,KIAA1107,AHCYL2,CRB1,TMOD1,TNS1,TRIO,FAM155A,REEP1,PHTF2" Drug 3362_UP Iodixanol [92339-11-2]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ARID1A,ADORA1,MRTFA,SEMA7A,SLC4A4,CFLAR,SLC16A4,CBFA2T2,CHRNB2,STOML1,PICK1,AKAP6,WHRN,ENTPD4,MICAL2,GREB1,RIMS2,HS3ST2,CDON,HIPK3,LRRC23,ERCC2,VPS26C,FAM198B,KIAA1109,DLL3,FYB1,GABRG2,SEPT9,GNAS,GSTM5,KLF12,DHX35,ICA1,INPP5B,KCNMA1,MSR1,TAGLN3,MYCN,FXYD7,NF1,OMG,KCNK10,SAMD9,GDPD2,SNRK,RPS6KA2,KCNIP1,SELL,COA1,ZCCHC24,ARHGAP26,FAM189A1,THRA,TRIO,ADAMTS9,PLSCR4" Drug 4736_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASIC1,BRINP2,ATP1A2,ATP2B2,SCAPER,MTMR7,TMEM257,CDH8,CHGA,CYBB,SPOCK3,KBTBD11,ATN1,ELAVL3,SRPK3,C3orf18,LRRC23,RASGRP2,PTK2B,DLC1,FGFR1,FHL1,EFCAB2,GABRA2,LPAR4,GRIA1,SPACA9,GRM8,SYNPO,HPCA,KCNJ5,KCNMA1,AFDN,ADAM22,BCO1,NCAM1,NPY,NTRK2,PALM,CDK18,MAPK7,PTN,C1orf54,RYR1,PPP1R9A,NLGN1,SLC11A1,ZNF415,PEG10,MAPK8IP3,POPDC3,TAL1,AMACR,LAT2,KCNAB1,TIGD6,JPH3" Drug 4238_UP Seneciphylline [480-81-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "NME5,PKP4,APBB1,KCNAB2,PPP4R4,ATP6V0A1,HAP1,CAPN3,CBS,SEPT7,ASIC3,SLC22A6,COL9A3,NRG2,CNTNAP2,RIMS2,MFAP3L,CHRDL1,ECM2,EDNRA,SEMA3D,ELAVL3,PTK2B,CAMSAP1,FLT1,HBS1L,PCDH17,CSDC2,RND1,GPER1,GRM7,NXPH3,IL6ST,DIPK1A,KHK,TAGLN3,NPR2,NPTX1,NTRK3,CNNM2,PTCH1,GAL3ST4,RGS4,TCP11L1,KCNIP1,RTN1,OGDHL,SNAP25,ZHX3,SPTB,NFASC,ACSBG1,TPM3,LAT2,ZNF225,NT5M,KCNAB1" Drug 6241_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ALK,AMT,APBB2,AZGP1,ADGRG1,NMT2,QKI,RGS6,LRIG1,FAM169A,SDC3,BRINP1,ATN1,GNE,SUGP2,DLC1,ST3GAL6,ZNF589,BAIAP2,FHL1,CINP,HBS1L,AHDC1,RND1,TXNL4A,POLL,GRM1,GUCY1A2,HPSE2,INPP5B,KCNF1,KIF2A,AFDN,NNAT,SNRK,WDR25,CEP97,RGS12,RPS6KA2,PAQR6,SGK1,SYBU,RPH3A,KANSL3,TSNAXIP1,SPTAN1,SEMA4A,WSCD1,ATP13A2,AP4E1,THRA,KAT6B,CABIN1,TPD52,MICAL1,SYNC,SCG2" Drug 5043_UP Piracetam [7491-74-9]; Up 200; 28.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "AK2,ADGRF5,APC,AQP4,ARRB1,PDE8B,DDX3Y,BMP7,USP2,CDH8,CRLF1,CNTN1,AKAP5,RGS6,RIMS2,RIMS3,PHYHIP,MFAP3L,EDNRA,SEMA3D,MTSS1L,PRELID3A,GABRA2,GAP43,GRIN1,CACFD1,GRM7,ITIH2,KCNJ3,KCNMA1,KIT,MATN3,AFDN,KCNK10,ENPP2,GPR85,PFKFB2,PPARA,LRRN3,GRAMD1C,TMEM206,EMID1,ZNF821,SLA,SLC9A5,SLC12A4,SLCO1A2,SNCA,FAIM2,SPTB,PHLDB1,RALYL,TRO,RPRM,MKRN3,STMN4,SEMA3B" Drug 3678_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADD2,NME5,AMH,ASTN1,BACH1,BMP7,CACNA1I,NEURL1,CHI3L2,RAB26,FHL5,COL9A3,CRMP1,EDRF1,FRMPD4,TOX,RIMS3,RABGAP1L,ARNT2,DTNA,EFNB3,AASS,RGS17,ETV1,GAB1,ALDH1L1,ADAM28,GFER,RND1,HPGDS,GPM6A,GRIK2,FAM107A,PTGDR2,MAPT,MMP16,MMP17,LYRM9,STRN3,RFX2,SLC15A2,SCN3B,ZSWIM8,NPAS3,ATP10B,INKA2,SYT1,ATP11A,PCDHGA10,HIF3A,TNS1,TRO,FLRT1,ZNF24,ZNF225,KCNAB1,EPM2A" Drug 3877_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "GAS7,DNAH17,SLC4A4,CACNA1I,CFAP410,CAMK2B,CBARP,CHRNB2,LY86,CNTFR,AKAP7,IQCK,IFFO1,CRMP1,CNTNAP2,NOS1AP,DCT,CNIH3,DYNC1I1,EDNRA,FOXG1,GAB1,PCDH17,GLYR1,PRUNE2,GRIK5,GRM2,KCNJ4,KCNJ5,KITLG,MMP16,ADAM22,NCF2,NELL2,NOVA2,PCBP3,OPRL1,C19orf57,MINDY2,PTAFR,TTLL7,CARF,SH3GL3,SLC2A5,SLN,SNAP25,IZUMO4,HECW1,SPART,MAPK8IP3,KAZN,TBCEL,SLC35G2,THRA,TRO,TRPM2,KCNAB1" Drug 4530_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "RALGAPA1,ASPHD1,C1QTNF1,APC,APOC1,KIF1A,CBFA2T2,ARHGEF2,CDH10,AKAP5,SLC4A8,CREB5,ABCG1,MFAP3L,EDIL3,EDNRA,SIDT2,MRNIP,C3orf18,FGFR1,PRELID3A,USP19,MSL3,GRK4,GRM1,KLF12,SHISAL1,IL6ST,ITPKA,MN1,MX1,NDP,PALM,PCDH9,LRP12,SAMD9,CNTLN,RAB3A,PID1,RPS6KA2,FUZ,PPP4R3A,FAM214B,CCDC88A,SNCA,WDTC1,TROVE2,NCDN,ASTN2,ARHGEF12,TRIO,AMACR,ZMYND8,RPRM,NDRG4,NAV3,PCBP4" Drug 5793_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASPHD1,ASIC1,PLA2G6,FGD2,DDO,PPP4R4,BMP7,MYRF,BTRC,CACNG1,LDB2,B4GALT6,AKAP5,SH2B1,CRMP1,ST18,NOS1AP,SPOCK2,PLPPR4,DYRK1A,EZH1,ATP8A1,SEMA4D,AFF2,GABRA2,GAP43,GATM,GPM6A,KCNN1,MAPT,NCAM2,NPPA,PLP1,WDR25,PLPPR1,PTPRB,PID1,ACSS3,SUSD4,ROM1,EMID1,STUM,RASA3,SHANK2,SLN,KIF13A,DOP1A,SP4,NFASC,DMXL2,TEX15,DAAM2,SEZ6L,TPM1,SLC17A7,KCNAB1,DPF3" Drug 3925_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "KDM5D,ADRA1D,AGT,C1QTNF1,AMH,MARK4,ATP1A2,ATP1A3,SYNJ2,GYG2,CACNA1I,CAMK2B,INA,CDH2,DNAJB5,NCOR2,OSBPL3,CTIF,GSDME,NTM,EFNB3,ELAVL3,TNK2,ERCC2,APC2,ETV1,FOXG1,SORBS1,GAD1,ATP8A2,POLL,GPR12,GRM1,SCRG1,IFI16,IL11RA,ITGA7,KCNC1,MDFI,MSI1,GAL3ST4,MYH14,SYNDIG1,KCNIP1,FRMPD1,ST6GAL1,PKNOX2,FAIM2,NMNAT2,VAMP1,SMG6,TK2,TNS1,TRO,LAT2,XRCC4,KCNAB1" Drug 4231_DN Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "RALGAPA1,MRTFA,CDK13,PDE8B,SLC4A4,ADAM15,MAP7,CLCN4,DNAJB5,HOMER3,ENTPD4,CSNK1E,VCAN,CNTNAP2,EDRF1,RABGAP1L,DTNA,TOM1,EDN1,FCF1,FAM13A,MBNL2,STX2,ZNF589,FGFR1,RUNDC3A,GLYR1,TDRKH,INPP5B,KCNN1,LSS,NEK1,PAK3,PDE4B,CDK14,PIK3R1,TNPO2,MINDY2,RGS10,KCTD17,GSTCD,FBXW7,TRAPPC13,SAFB,CSRNP3,ZNF821,SLC1A7,PPP4R3A,TRIM2,AHCYL2,GPR161,SLC44A1,THRA,TPM2,AMACR,REEP1,KCNAB1" Drug 6348_UP Iopanoic acid [96-83-3]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ARID1A,MTUS1,AMT,SEMA7A,SEMA4G,PDE8B,DNAH17,CADM3,KSR1,BMP7,ARHGEF1,CNR1,AKAP7,AKAP6,ENTPD4,NCOR2,AATK,CNTNAP2,CTNND2,G3BP2,TOM1,DUSP9,EDIL3,SIDT2,EGFR,LRRC17,ERAP1,GNG3,GRIK2,SPACA9,IRF8,IL6ST,KCNB1,KCNJ5,KIF5A,GIT1,NELL2,NF1,NNAT,PDE3B,PPARA,SCN8A,IL17RB,FNDC3A,CEP68,ACSBG1,ATP13A2,TLR4,R3HDM1,SMUG1,TRIO,LAT2,PARP6,STMN4,KCNAB1,NUP214,DPF3" Drug 6506_UP Alfadolone acetate [23930-37-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASPHD1,ADORA1,AK2,LTBP4,BEGAIN,SEMA7A,AQP4,BAIAP3,CAMK2G,CBFA2T2,CNN3,PICK1,COL9A3,NECTIN3,VCAN,GREB1,GIT2,RUSC2,KBTBD11,ATN1,EFNA3,ELAVL3,RASGRP2,B3GAT1,GALC,SIGLEC8,GCNT2,GSTM5,HMGCR,DHX35,KCNJ4,KCNMA1,KCNN1,MOBP,ADAM22,MX1,GPR85,NLE1,EPN1,PTX3,ATG16L1,RGS3,GSTCD,FBXW7,KCNIP1,SBF1,ASAP3,PREX2,ZHX3,ARHGAP26,IQCE,TRIM2,ZNF34,SLC44A1,TRPC3,FLRT2,LAT2" Drug 2435_UP Bisacodyl [603-50-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADD2,ANK3,AQP4,ARRB1,ALDH4A1,CCDC181,NRP2,SYNJ1,FUBP1,CACNA1I,CDH10,LARGE1,CNN3,WHRN,IFFO1,NRG2,SEC14L5,SNPH,BRINP1,DLG3,CDON,SEZ6L2,EEF1A2,EIF1,EPB41L1,ZNF391,SRCAP,POLL,LILRA2,STON1,GUCY1A2,KCNH1,KIFC3,MDFI,AFF1,MMP16,NCAM1,PGAM2,STRN3,SYTL2,WDR25,RASGRF1,SHANK2,SLCO1A2,WDTC1,SOX15,SYN2,SYT1,CAMSAP2,TRIM2,PSD3,RBFOX2,TRPC3,ZMYND8,LMF1,EVI5,KCNAB1" Drug 3794_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASPHD1,ADCY2,NME5,BIN1,SEMA7A,PKP4,KCNAB2,EPB41L5,BMP7,CBS,ARHGAP33,TPP1,AKAP7,IFFO1,TCEAL2,CREM,RIMS2,MFAP3L,DUSP9,PRELID3A,MSL3,KCNMB4,GPM6A,GPM6B,ELOVL5,SCIN,ITPKA,KIFC3,KIT,LMO2,MAP2,CLDN11,PBX1,PFKFB2,KCTD15,PLXNB1,PLPPR1,RAB3IL1,RAD52,TMEM206,RASA3,ASAP3,NTNG1,ST6GAL1,FAM214B,ARHGEF40,SLC9A5,RBM34,TSNAXIP1,ZHX3,LHPP,THSD1,PLCB1,DOCK9,VGF,WIPF1,SMIM8" Drug 6500_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "AK2,ALK,BEGAIN,AMPH,SEMA7A,APOC1,CDK13,ALDH4A1,CADM3,SCAPER,CA4,CALB2,CAMK2G,P2RX6,SLC4A8,HAPLN1,CHD5,TBC1D5,HP1BP3,ATN1,RCAN1,DTNA,EFNB3,MBNL2,ING4,OLFM1,FHL1,ANKFY1,POLL,GNAS,RAPGEF1,KCNN2,MATK,MGAT3,MMP16,CD200,DUSP26,PRPH,PTPRD,NUDT11,RTN1,SBF1,SCN2B,FNDC3A,SLC1A7,RIMS1,COLGALT2,ST5,TRIM2,ZNF34,TLR4,CHST5,AMACR,NSD2,XRCC4,SLC30A3,JPH3" Drug 2773_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASIC1,ADORA2A,NME5,APAF1,APC,MARK4,ALDH4A1,CADM3,ST3GAL5,CFAP410,RCBTB2,ZFYVE9,HOMER3,PICK1,CNTN1,AKAP7,RCHY1,CREM,CRMP1,ARHGEF10,KBTBD11,SHANK1,DYRK1A,EFNA3,MBNL2,SPEG,ANKMY1,CAMSAP1,C1orf61,GAB1,GPM6B,NR3C1,MAP4,GIT1,NF1,EPN1,PLTP,LRP12,PRRX1,MINDY2,MAPK8,PTPRE,RFX2,ZFHX4,CARF,RYR1,ASAP3,BCAN,CXXC4,IQSEC2,SYT11,TBCEL,ZEB1,TPM3,UCHL1,KCNAB1,EPM2A" Drug 5778_DN Ebselen [60940-34-3]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ABHD6,ADD2,AP2A2,C1QTNF1,BIN1,AMT,PPFIA3,APP,CDK10,PDE8B,CAMK2B,SLC25A14,CHM,KIAA1549L,CPS1,CREM,TENM4,CSF1R,PDE4DIP,SLITRK5,KIAA0513,DPH1,EFNA3,EGFR,MRNIP,PLEKHO1,PCDH17,C1QL1,SHISAL1,TJAP1,IL11RA,KHK,MATN3,PBX1,CDK14,MINDY2,PTPRN2,RGS7,MYH14,MCMBP,CCDC88A,BTBD7,TROVE2,RGL1,PLCB1,COBL,IQCE,TCF4,ARHGEF12,TK2,TNS1,TRPC1,SSBP2,FAM155A,LMF1,ZNF74,KAT6A" Drug 2934_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ABHD6,BIN1,ANK3,DDX3Y,ALDH4A1,CFLAR,CACNA1I,RUNX1T1,CBFA2T2,SYNGR3,REPS2,ARHGAP33,B4GALT6,TAOK2,EPS15L1,CNTN1,CREM,DBN1,ATN1,EDNRB,CELSR3,FAM13A,MRNIP,KAT8,BAIAP2,C1orf61,FYB1,SEPT9,GLRB,HTR2A,ITPKA,KHK,KIFC3,SCAMP5,CD200,ZNF862,NINJ2,NPTX1,NTRK2,PDE4D,DUSP26,SLC25A23,PPARA,PTPRN2,GTDC1,RGS10,ZNF821,HKDC1,CCDC88A,IQSEC2,IQCE,TMOD1,VIPR2,LMF1,CLIP2,WNT7A,MKRN3" Drug 4620_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADCY6,ADORA2A,GAS7,CDK10,CCDC181,CADM3,RGS11,BMPR1B,CDK5R1,RUNX1T1,DGKI,NRG2,SH2B1,CSF1,CNTNAP2,CTNND2,NOS1AP,CTIF,SRGAP3,ABCC9,EDN3,EDNRB,AGAP2,PDLIM5,FYB1,SIGLEC8,NEU3,GPER1,HTR2A,ITGA7,KCNA2,KCND3,MMP16,ADAM22,NF1,CLDN11,ST8SIA5,PPP1R1A,PTCH1,SUSD4,RASGRF1,RGS12,ROM1,NEK11,TCP11L1,SLC4A3,SLC8A2,BTBD7,ZNF423,BEX1,ARHGAP26,ASTN2,MCF2L,TMOD1,TNS1,SCG2,GAN" Drug 7244_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "RALGAPA1,MTUS1,NME5,MRTFA,PPFIA1,CASK,MARK4,ALDH4A1,ALDH7A1,SYNJ2,MAP7,CBFA2T2,CHN2,QKI,HOMER3,NRG2,CTNND2,EFNA3,EGFR,MRNIP,FYB1,SYT17,USP19,COPS8,GLS,MSL3,HLF,SYNPO,INPP5B,ITPKA,KCNMA1,KIF5C,MIA2,MN1,NCAM1,LRP12,FA2H,MAPK7,PTPRE,TMEM231,KHDRBS2,ZFP30,ITSN1,SLC1A3,SLC9A5,ZNF334,SPTAN1,SS18,ELOVL4,CEP68,VAMP1,SMG6,ARHGEF12,VIPR2,HPS4,PHTF2,DPF3" Drug 4501_DN Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADD1,PLA2G6,MRTFA,AMT,SEMA4G,MARK4,ALDH4A1,SLC4A4,BTRC,CACNA2D2,LY86,PICK1,CSF1R,DAPK3,SIDT2,EGFR,HSD17B14,FGFR1,FYB1,SEPT9,SRCAP,GLYR1,GPM6B,IL6ST,KCNJ5,KIF5C,LSS,ADAM22,LYRM9,ZNF862,NF1,TNPO2,PTPA,MAPK7,MAPK8,PTCH1,RAD52,GSTCD,TCP11L1,SH3BP2,ITSN1,AMBRA1,SLC4A3,SLC9A5,SLC14A1,ZNF667,KDM4B,MAPK8IP3,CEP68,COBL,ATP11A,SMUG1,RPRM,NT5M,SEMA3B,SNX27,WIPF2" Drug 6605_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "PLA2G6,LTBP4,ALK,ANK2,GAS7,DDO,ASCL1,BACH1,CAMK2B,CAPN3,ARHGEF2,SEPT7,CRLF1,CHI3L2,RAB33A,ARHGEF10,VCAN,PDE4DIP,BRINP1,MFAP3L,SRGAP3,CHRDL1,DYRK1A,EDNRA,PIPOX,DLC1,GATM,RUNDC3A,PRUNE2,GPM6A,GRIK1,IGFBP1,INPP5B,AFF1,MOBP,NF1,NTRK3,PCDH9,PLXNB1,PPARA,WDR25,ZSCAN2,SCN2B,MRAS,SLC8A1,SPTB,DDN,PHLDB1,PLCB1,SYP,TACR1,MCF2L,THRA,UGT8,LAMP5,PRDM2,SLC17A7" Drug 3361_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "DPF1,ARID1A,NDRG2,BRAP,AGT,NME5,APBA2,ATP2B2,CACNA1I,ARHGEF1,WHRN,IFFO1,CRMP1,ATRNL1,CNTNAP2,RIMS3,SPOCK3,DTNA,DMTN,EPHB1,SPEG,PIPOX,PTK2B,CORO2B,ZNF589,KIAA1109,CAMSAP1,FHL1,FOXF2,RASL10A,GAD2,GLS,ADAMTS13,GRM1,KCNMA1,KCNQ3,MATN3,AFF1,MMP17,CD200,TAGLN3,NEUROD1,NF1,NPTX2,PAX6,ENPP2,RAB3IL1,TRIM68,SEMA6D,ASIC4,SLCO1A2,CXXC4,ZCCHC24,PCDHGA10,PSD3,TRPM2,DNALI1" Drug 2404_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ASPHD1,CDC42BPA,AQP4,PRX,ARRB1,CDO1,DLGAP1,HOMER3,CPS1,CRMP1,CSF1R,PPP1R16B,RIMS2,EDRF1,JAKMIP2,DNAH9,DTNA,LPAR6,MRNIP,EIF1,RASGRP2,CDKL3,DLC1,OLFM1,SORBS1,GFAP,GFER,GLYR1,PRUNE2,CACFD1,GRM1,GRM8,KCNK1,SLCO1C1,NUMA1,PPARA,FBXW7,CCDC92,NLGN1,SLC1A3,ARHGEF40,NPAS3,RAP1GAP2,CLSTN2,THSD1,SS18,PDLIM2,PSD3,CRTC1,SPX,TIAM1,TMOD1,AMACR,FLRT2,FLRT1,PLSCR4,GAN" Drug 3940_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "AMT,CDC42BPA,APBA2,ATM,CACNA1I,CFAP410,CACNA2D1,CACNG1,NEURL1,SEPT7,LY86,CRY2,SNCAIP,PLXNC1,ELAVL4,ELN,OLIG2,ERCC2,ZNF391,FOXG1,HPGDS,POLL,GNAO1,STON1,GRM7,PTGDR2,ICA1,TJAP1,LRP1B,NTRK2,NTRK3,PFKFB2,EPN1,CDIP1,CEP41,GDPD2,RAB3A,TRIM68,RAVER2,RYR1,SCN8A,CNKSR2,SLC1A7,FAIM2,SOX10,NMNAT2,ATP10B,ZC4H2,ATP11A,TMOD1,CHST5,TRPM2,HIRA,TUBB1,ADAMTS9,SSPN,AP3B2" Drug 3411_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "RALGAPA1,ABR,C1QTNF3,SRPX,APOC1,PDE8B,MARK4,ALDH4A1,CDH10,TAOK2,CRMP1,CSF1,CTH,MAML1,DAPK3,MFAP3L,RUSC2,RCAN1,SORBS3,EML1,HSD17B14,ERCC2,FAM198B,FGFR1,GLI2,MSL3,TDRKH,GRB10,GSN,INPP1,ITIH2,KHK,MIA2,KITLG,KCNK10,POLG,RAD52,ZDHHC14,RGS12,MYH14,TMCC1,ZCCHC24,PHLDB1,POPDC3,EXOC7,IQCE,PRMT8,TRPC1,VAV2,MICAL1,XRCC4,SPHK2,REEP1,ITM2C,ST7,RNF170,SSPN" Drug 335_UP nifedipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "LTBP4,ALK,BIN1,CDC42BPA,ANK1,ANK2,APBB1,KIAA1614,ARNTL,ATP6V0A1,CA8,DLGAP1,CHD5,CALY,CYBB,HDAC4,DBT,SIDT2,EFNB3,EPHB1,SPEG,CORO2B,FGR,TBR1,FYB1,GLRB,GRK4,RASSF8,ATXN2L,INSM1,KCNMA1,L1CAM,CD200,ADAM22,NF1,SLC11A2,NRGN,CDK14,POLG,PPP2R2B,MASP1,GAL3ST4,RGR,EMID1,FOXRED2,RASA3,SH3GL3,ASAP3,SLC1A7,ZCCHC24,LHPP,TAL1,TBL1X,PARD3,RBFOX2,PLPPR2,MVB12B" Drug 6043_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ACTN2,LTBP4,AMT,CDC42BPA,CCDC181,ADAM23,BACH1,KSR1,BSN,HIP1R,CHI3L2,CHN2,TAOK2,STOML1,MYRIP,NOS1AP,RUSC2,HSD17B14,ERBB4,ACSL4,ZNF589,FGF1,BAIAP2,SORBS1,GAD1,SIGLEC8,GPR162,RUNDC3A,GLRB,PRUNE2,CACFD1,GRM7,HLF,HPSE2,SYNPO,KIT,OLR1,PTAFR,FAM120C,C1orf54,RASGRF1,RGS4,RYR1,RASA3,SLC1A2,RPH3A,SLC1A7,SLC9A5,CXXC4,MYH15,PHLDB1,GPR161,TMOD1,TNS1,UCHL1,VAV2,KAT6A" Drug 5792_UP Butamben [94-25-7]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ADD2,TRMT9B,EPB41L5,DDO,BCAS1,ASTN1,NRP2,CACNB2,CBLN1,CD86,ARHGAP33,LARGE1,ARHGAP22,RCHY1,NOS1AP,ARMCX2,RABGAP1L,ARNT2,COQ7,LRRC17,FABP7,CAMSAP1,DISC1,ATP8A2,GATM,ALDH1L1,GFRA1,GPD1,GPM6B,GRIK5,GRM1,ELOVL5,ITGA7,KCNH2,KHK,MATK,NTRK2,PDE3B,PFKFB4,CEP41,PTPRN2,FAM120C,RIT2,PNMA8A,STUM,NTNG1,PPP4R3A,KIF13A,KAZN,TCF4,AMACR,ZMYND8,FLRT1,VSNL1,REEP1,SLC30A4,PARP11" Drug 6106_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "ACTN2,ALCAM,AMPD3,AMPH,KCNAB2,PPFIA3,CDC14B,CACNA1D,HAP1,HIP1R,ARHGEF1,NEURL1,RAB33A,PDE4DIP,CNTNAP2,ARHGEF4,MFAP3L,RUSC2,DMPK,DTNA,EFNB3,F5,ZNF589,GAB1,SEPT9,SRCAP,GFER,NR3C1,RASSF8,INPP5B,KCNMA1,KCNQ3,KPNA5,LIG4,VWA5A,MOBP,NELL2,MAPK7,WDR25,GSTCD,RASA3,FRMPD1,SLC1A7,SLC8A1,SHANK2,SNAP25,KIF13A,NCDN,MAPK8IP3,POPDC3,KAZN,TBCEL,WSCD1,DOCK9,VIPR2,ZNF711,NT5M" Drug 5274_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.86E-06 9.10E-02 4.26E-05 4.85E-04 57 197 "SYN3,ADD2,NME5,ATM,KSR1,KALRN,SLC16A4,FAM189A2,PICK1,SNCAIP,ARHGEF10,SDC3,GREB1,RIMS2,SRGAP3,TMCC2,DMPK,DTNB,DUSP9,DYRK1A,ST8SIA3,EDNRA,SUGP2,VPS13B,CACNG3,FOXG1,ZNF274,GAP43,SRCAP,GPM6B,SOX21,KCNJ5,KIT,AFDN,MMP16,NEFM,NELL2,PCBP3,PDE4B,PIK3CD,PRKCB,RELN,SNRK,PTCH1,PID1,CCDC40,SEMA6D,ZNF821,SH3BP2,SLC1A7,PKNOX2,SNCA,PDZD2,ICAM5,TLL2,R3HDM1,EVI5" Drug CID000119582 Joro spider toxin Stitch 1.95E-06 9.53E-02 4.46E-05 5.07E-04 20 43 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GSN,NASP,NUP214" Drug CID000003932 linopirdine Stitch 1.95E-06 9.53E-02 4.46E-05 5.07E-04 20 43 "ANK3,ATP2B1,ATP2B2,ATP2B3,BSN,CHRM1,CHRNA4,DMPK,KCNMB4,KCNC1,KCNH1,KCNH2,KCNMA1,KCNQ2,KCNQ3,OPRL1,RPS6KA2,ARFGAP1,TNS1,SLC17A7" Drug 1891_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A" Broad Institute CMAP Up 1.97E-06 9.64E-02 4.50E-05 5.12E-04 53 179 "ABHD6,ADRB2,MTUS1,AGT,ARNTL,MARK4,ZBTB10,ST3GAL5,HIP1R,NMT2,CSNK1E,CTH,C2CD2L,FAM13A,MBNL2,F3,TAOK3,TESK2,BAIAP2,FYN,GLS,TDRKH,GUCY1B1,KLF12,DIPK1A,KIF5C,MEF2C,TAGLN3,PCDH9,RETREG1,SMOX,PPM1B,PKIA,PTCH1,RGS4,LGR4,SH3GL2,ASAP3,SLC11A1,KDM4B,ZCCHC24,FNBP1,THSD1,ELOVL4,CEP68,RGL1,KLHL7,SYT1,TGFBR3,HEY1,SSBP2,DNAJC12,EVI5" Drug 5086_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.97E-06 9.64E-02 4.50E-05 5.12E-04 53 179 "ADRB2,APAF1,ARNTL,NOL4,RGS9,ST3GAL5,CACNA2D1,HIP1R,USP2,CHN2,CRY2,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,PLPPR4,EFNA3,RGS17,TAOK3,TESK2,BAIAP2,SORBS1,FYN,GLS,STON1,GUCY1B1,DIPK1A,ITGA7,KIF5C,MAPT,PCDH9,PDGFRA,SERPINI1,RETREG1,PRPH,TMEM231,ENOX1,RGS4,RPS6KA2,SH3GL3,SLC2A5,TNIK,ZCCHC24,ARHGAP26,MAPK8IP3,CEP68,RGL1,SYT11,SYT1,DNAJC12,LAT2,DPF3" Drug ctd:D015632 "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine" CTD 2.04E-06 9.99E-02 4.66E-05 5.31E-04 82 317 "SYN3,ACHE,ADORA2A,API5,ARRB1,KIF1A,CFLAR,CDK5R1,CDK5R2,CALM1,NGB,SYNGR3,SEPT7,CDC42,CHRNA4,PLAA,ABCG2,SNCAIP,CST3,PNPLA8,CX3CR1,DPYSL2,DRD1,PDCD6IP,GOLT1B,EFNB3,EIF5,TNK2,EN2,ENO2,MRPL10,PPP1R1B,FYN,GAB1,GAD1,GAP43,GFAP,LPAR4,GRIN1,GRM1,GRM5,HBA1,HSP90AA1,IDH3A,KIF5A,STMN1,SMAD1,MAOB,MAP2,MAPT,MT3,NCAM1,NFE2L2,NOS1,PDYN,PENK,SH3KBP1,PPM1B,MAPK3,PPP2R3C,RAB3A,RET,LRRK2,SMPD3,SFPQ,RASA3,CLSTN1,SNCA,KIF1B,SRPK2,JMJD6,SYT4,TJP1,CBX5,TLR4,KAT6B,NPL,UBC,UCHL1,MTCH1,MAP3K12,TUBA1A" Drug CID000002890 CX546 Stitch 2.04E-06 1.00E-01 4.67E-05 5.32E-04 13 21 "NRP2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRM2,GRM3,GRM5,NELL1,NELL2,NETO1" Drug CID000002351 bepridil Stitch 2.05E-06 1.01E-01 4.69E-05 5.34E-04 41 126 "ASIC1,ATP1A1,ATP2B1,ATP2B2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,KRIT1,CACNA2D2,ASIC3,CHRM1,CALN1,CACNG7,CACNG3,CACNG2,MYLK2,KCND3,KCNH2,PKD1,RYR1,RYR3,SBF1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC8A2,SLC8A3,SHANK2,SCN3B,TPCN2,MFF" Drug 5218_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "ALK,MRTFA,AMT,APBB2,ASPH,CFAP410,CA4,SLC16A4,CDO1,TAOK2,HOMER3,ARHGEF10,GREB1,MBNL2,ING4,ELAVL3,LRRC23,CORO2B,FGF12,AGAP2,HBS1L,PCDH17,GLYR1,MSL3,GRIK5,GSTM5,GUCY1A2,ICA1,ITGA7,KCND3,KCNN2,MAP4,MYL3,ZNF862,NOVA2,PLCD1,PPP5C,WDR25,ZSCAN2,C1orf54,RGS10,TCP11L1,SELL,FAM214B,WDTC1,HECW1,SPTAN1,ATP10B,STX1A,SYT5,KIAA1107,TPM3,XRCC4,MARCH8,ZNF248,TIGD6" Drug 1696_UP Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "NDRG2,ADRA1D,APLP1,ASPH,CACNB2,GPR37L1,CNTN1,WHRN,SDC3,PHF14,GREB1,ARHGEF4,EDRF1,RIMS3,NR1D2,DTNA,FEM1B,EGR3,HSD17B14,GAD2,ERAP1,TXNL4A,NR3C1,INPP5B,JAK2,MATK,ADAM22,ZNF862,NF1,MAPK8,TMEM260,RAD52,RGS10,SGK1,SH3BP2,SYBU,PALLD,KDM4C,SPTAN1,INKA2,PRRC2C,PLCB1,ARC,DNMBP,KIAA1107,TRIM2,RPGRIP1L,CRTC1,SLC44A1,ZKSCAN5,CADM1,PDIA2,VLDLR,ZNF45,SEMA3B,NAV2" Drug 3634_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "ACTN2,AP2A2,PLA2G6,APLP1,APOC1,DNAH17,RASL11B,ALDH7A1,BAIAP3,CA12,CLGN,CRY2,MFAP3L,DTNA,TSPAN5,EDNRA,CNNM1,SUGP2,PLXNC1,TUBB4A,FOXG1,PDLIM5,CGREF1,FYN,GPER1,CNTRL,ITIH2,KCNN2,MIA2,NUMA1,PDE3B,PFKFB2,RETREG1,PLCD1,EPN1,PPP5C,TMEM104,ZSCAN2,RAB3IL1,KCTD17,TCP11L1,ZNF821,SLN,CXXC4,SMARCD3,DOK5,KDM4C,ARHGAP26,POPDC3,TBCEL,DOCK9,ARHGEF12,PCDHA5,DNAH7,ZKSCAN5,MAP3K12" Drug 5024_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "ALCAM,PLA2G4C,CFLAR,BMP7,CA12,CACNA1D,SLIT2,LHX2,CLU,ENTPD4,CSF1R,PDE4DIP,DOCK4,DCAF8,MFAP3L,EFNA3,EN2,ANKMY1,ACSL4,FECH,FGFR3,BAIAP2,PRELID3A,USP19,ZNF276,MSL3,FERMT2,GPR37,NR3C1,INPP5B,KCNJ3,IPO5,MAP4,MYO9A,SLC11A2,NUMA1,OGDH,RETREG1,LRP12,PRPH,WDR25,CEP97,ROBO1,CPEB3,ZKSCAN3,CDK19,SPART,STX1A,PLCB1,TCF7L2,ARHGEF12,CRTC1,ZNF34,WNK1,MVB12B,KAT6A" Drug 1480_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "SEMA6A,BIN1,CDC42BPA,APBB2,APOC1,PPP4R4,RGS20,ARRB2,ALDH4A1,SLC4A4,BACH1,MPDZ,CFLAR,ST3GAL5,SCAPER,CALB1,ARHGAP33,STOML1,QKI,COL4A5,CREM,DNAJC6,LYPD1,DPYSL2,DSCAM,EDNRB,APC2,FGF13,FGFR1,IQCG,ZMYND11,GHR,STON1,KCNN1,KIF5C,VWA5A,MDM4,MEF2C,KITLG,NF1,NPTX1,CEP41,PRKAR1B,FAM120C,CEP97,FAM184A,FBXO11,PPP4R3A,KDM4B,SPTB,SPART,AJAP1,CRTC1,TMOD1,BEX4,WIPF1" Drug 6643_UP Thioguanosine [85-31-4]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "RALGAPA1,ASPHD1,ACHE,SYT13,AMPH,GAS7,PPP4R4,CACNB4,CAMK2B,DGKI,CDH10,CHGA,VAX2,TOX,SPOCK2,CTIF,DTNA,ELN,CACNG2,DLC1,ST3GAL6,FGF1,PDLIM5,SIGLEC8,GFER,RND1,STMN2,HPSE2,HTR2A,KCNJ5,KCNN1,LSAMP,ADAM22,NACA,NCAM1,NOVA2,PALM,PDE4A,PENK,PPP1R1A,MAPK8,RASGRF1,PAQR6,SCN2B,ZNF334,PDZRN3,RBM34,ZBTB43,ACSBG1,SYT5,PHF24,TEX15,DICER1,AP4E1,TRPC3,KCNAB1" Drug 4179_DN Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "ASPHD1,MRTFA,AMPD3,APC,CFLAR,CAMK2B,QKI,SNCAIP,NOS1AP,DAPK3,SRGAP3,TMCC2,DTNA,SGK2,HIPK3,EFNB3,ING4,VPS13B,COQ7,ERCC2,ZNF589,OLFM1,CGREF1,SEPT9,RND1,GLYR1,MSL3,EML4,ADAMTS13,GSN,ICA1,KCNJ3,VWA5A,KITLG,ADAM22,MX1,NF1,SERPINI1,MINDY2,PPP5C,PRKAR1B,PTHLH,RAD52,KCNIP1,SLC2A5,IQSEC2,TROVE2,THSD1,SYT5,POPDC3,EXOC7,TCF7L2,AP4E1,ZNF34,ZMYND8,EPM2A" Drug 4503_UP Furosemide [54-31-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.07E-06 1.01E-01 4.71E-05 5.36E-04 56 193 "ACTN2,AK2,PKP4,APAF1,CDK13,CFLAR,BMP7,WASF1,CNTN1,CNTNAP2,MYEF2,DTNA,ECM2,PLXNC1,EPB41,KCNMB2,IGSF6,ETV1,DLC1,FGFR1,C1orf61,FAM49B,MSL3,GPM6B,GRIK5,CACFD1,GRM7,ICA1,IRF8,KCNN1,SMAD1,MDM4,MMP16,NOS1,NPY,OPCML,NLE1,EPN1,STRN3,ELOVL2,RAB3IL1,RAD52,RGS12,SLC1A7,SHANK2,RIMS1,SNAP25,ZSWIM8,ARHGAP26,TROVE2,SMG6,CRTC1,ZFPM2,TNS1,TRIO,SPHK2" Drug CID000001226 "cis-2,3-piperidine dicarboxylic acid" Stitch 2.13E-06 1.05E-01 4.85E-05 5.52E-04 16 30 "BCS1L,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug CID000127894 LY293558 Stitch 2.13E-06 1.05E-01 4.85E-05 5.52E-04 16 30 "BSN,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 2185_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 1.05E-01 4.85E-05 5.52E-04 54 184 "ADORA3,BIN1,LGR5,ALDH4A1,KSR1,BMP7,MTMR3,CACNA1I,LDLRAD4,NEURL1,PLAA,NMT2,AATK,SIPA1L1,PDE4DIP,DCAF4,RIPOR2,ATN1,DSCAM,FAM13A,SORBS3,ETV1,TBC1D16,KHDRBS3,GPR153,ERAP1,ALDH1L1,LYVE1,GRIN1,GSN,IRAK3,KCNJ5,KCNK1,MBP,MDFI,NF1,NRCAM,NTRK2,CLDN11,SLC25A23,MARCH1,RNASE1,MYH14,ZNF821,FRMPD1,CPEB3,CLSTN2,SAMSN1,AJAP1,TMOD1,TNNT1,RPRM,ZBTB16,CAMK1G" Drug 4449_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.13E-06 1.05E-01 4.85E-05 5.52E-04 54 184 "DPF1,GRAMD1B,ADRA1D,SEMA7A,ATM,EPS15L1,DNAJB5,ARMC8,AKAP6,ABI3BP,CTH,EDRF1,GIT2,DBT,SMG7,SPOCK3,ATN1,EDN1,OLFM1,CAP2,GLI2,RAB30,MSL3,GPR37,SYNPO,IL6ST,VWA5A,MMP16,NACA,NAP1L2,GPR88,OPCML,OXTR,PDE1C,PDE4B,PDE4D,PDGFRA,PLP1,MBOAT7,PTHLH,PTN,ACSS3,RGS4,KCNIP1,SCN8A,HSPA4L,PDZD2,SP4,ARHGAP26,TBL1X,CDK20,HIRA,SF1,EVI5" Drug 7245_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.18E-06 1.07E-01 4.88E-05 5.55E-04 52 175 "ABHD6,ADRB2,MTUS1,EPB41L5,SHROOM2,ARNTL,MARCH3,ST3GAL5,HIP1R,REPS2,NRXN3,PDE4DIP,CTH,DNAJC6,C2CD2L,EFNA3,RGS17,F3,TBC1D16,TAOK3,ATP8A1,TESK2,FGFR1,BAIAP2,FYN,GLS,GUCY1B1,DIPK1A,KCNN1,KIF5C,PCDH9,SERPINI1,FA2H,PTCH1,PTPN13,RAB3A,RGS4,TTLL7,FBXW7,SH3GL3,ASAP3,WDR47,PALLD,TNIK,BEX1,ELOVL4,CEP68,RGL1,SYT1,DNAJC12,TRIM9,DPF3" Drug CID000003845 kynurenic acid Stitch 2.20E-06 1.08E-01 4.88E-05 5.55E-04 40 122 "ABAT,AK2,AMT,KYAT1,CHRNA4,CHRNB2,SULT4A1,GDA,EIF4G2,FGF1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,INPP5K,GLRB,GPT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,POU6F1,PORCN,ETNPPL" Drug 2358_UP Flutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADORA1,AMT,ANK2,APBB2,APOC1,SEMA4G,ARRB1,MARK4,NUMB,CADM3,KIF1A,SYNJ2,MYRF,LDLRAD4,CD38,CHN2,CHRNB2,SEC31B,SH2B1,ARHGEF10,DCT,SPOCK3,RCAN1,E2F5,ST8SIA3,SIDT2,ABI2,MRNIP,TUBB4A,ZNF589,C1orf61,GABRA2,MAN1B1,INPP1,IPO5,MDM4,MOBP,ZNF862,NPPA,NTRK2,PPP2R5C,PTAFR,PEX5,SUGCT,SCN2B,BCAN,SLC20A2,TSPYL2,ATP10B,ZC4H2,VAMP1,EXOC7,DOCK9,PSD3,TNS2,PARD3,KAT6B" Drug 7274_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "MTUS1,BIN1,KCNAB2,CDC14B,ASPH,SYNJ2,BTRC,SCARB1,NRXN3,CLCN4,HAPLN1,CSF1,SNPH,B3GAT3,FBXL5,RUSC2,SPOCK3,PLXNC1,PLEKHO1,LRRC23,ST3GAL6,TRMO,FYB1,SEPT9,GPR75,MSL3,GPR17,CACFD1,GUCY1A1,SHISAL1,IL11RA,DIPK1A,KIF5C,PLCD1,PPARA,MAPK7,PTPRN2,ARHGEF10L,DCUN1D2,TRAPPC13,MAPK12,PPP4R3A,SLN,OGDHL,RBM34,KDM4B,TSNAXIP1,THSD1,SS18,JMJD6,WWC1,PARD3,CABIN1,SCG2,KCNAB1,EPM2A,KAT6A" Drug 4278_UP Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ACTN2,APC,EPB41L5,ATP1A3,ATP2B2,PROM1,CFAP410,RUNX1T1,CLDN10,FAM189A2,PICK1,NCOR2,CSF1R,RIMS3,EFNB3,MTSS1L,ETV1,REEP2,ST3GAL6,RUNDC3A,GPR17,GRM2,PRDM5,SOX21,PADI2,HRH3,KHK,MAN2A2,PCDHGC3,PDE4B,PDE4D,CAMKV,C19orf57,POU6F1,PRKAR1B,MAPK8,PRPH,PSD,ZSCAN32,PTPRB,MYH14,RYR1,TRIM46,NTNG1,KANSL3,SLCO1A2,MCF2L2,INKA2,AJAP1,ACSBG1,VAMP1,ARC,TRO,CADM1,OSBP2,SLC30A4,DPF3" Drug 6721_UP Nitrofural [59-87-0]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "KIDINS220,ALK,AMPH,APC,GAS7,DDO,CDC14B,ARHGDIG,LDLRAD4,CALB2,CRMP1,SUSD5,PDE4DIP,PHF14,C2CD2L,DYRK1A,SEMA3D,PLXNC1,EFS,F5,DLC1,FGF1,PRELID3A,TRAF3IP2,ERAP1,RND1,GPR19,GPR22,GRIK5,PTGDR2,KLF12,INPP5B,VWA5A,MOBP,TAGLN3,NPTX2,PDE2A,RETREG1,PPP5C,GDPD2,PTN,PTPRB,MYH14,IL17RB,FBXO11,DZIP1,ANKRD6,PKNOX2,SLC9A5,SNAP25,DOK5,ZC3H13,BEX1,TIMP4,PARP6,KCNAB1,NLRP3" Drug 3324_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASIC1,ARID1A,ADORA1,NME5,LTBP4,AMPD3,KCNAB2,CDK13,KSR1,LDLRAD4,CFAP410,FOXN3,NRG2,SNCAIP,NCAN,RIMS2,RIMS3,DAPK1,SPOCK2,DMD,EDN3,MBNL2,PLXNC1,LRRC17,FGF12,FGFR3,KHDRBS3,FYN,DISC1,RND1,NR3C1,HLF,IL6R,ITIH2,MOBP,TAGLN3,STRN3,NECAB2,SAMD9,C1orf54,KHDRBS2,RGS3,RGS12,TMEM206,RASA3,SLC9A5,ZNF415,ARHGAP26,MAPK8IP3,AJAP1,ARC,TRIM2,DOCK9,TK2,LAT2,KCNAB1,TIGD6" Drug 2250_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "NME5,C1QTNF1,MRTFA,AMH,PRX,BRINP2,SCAPER,BAIAP3,ADGRG1,RAB28,FADS2,QKI,SLC4A7,AATK,CSF1,DCAF4,SPOCK2,DTNA,EDNRA,VPS13B,ERCC2,NCALD,DLC1,OLFM1,FHL1,AGAP2,GFAP,RND1,GPM6B,GRM7,ATXN2L,KCNQ3,MAP4,MGAT3,MOBP,BCO1,NF1,P2RY1,PCDH9,DCHS2,PLPPR1,ZMAT4,RGS12,SUPT20H,TRA2B,PPP1R9A,LIMS2,PKNOX2,SHANK2,SP4,TROVE2,ARC,POPDC3,KIAA1107,PCDHA5,CABIN1,WNK1" Drug 6557_DN AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "PPP4R4,ADAM15,CAMK2B,ARHGAP33,NRXN3,RAB26,SLC4A7,OSBPL3,CNTNAP2,TOX,RIMS3,RUSC2,SPOCK3,RABGAP1L,DPH1,CNNM1,EN2,SCML2,EFEMP1,FGF1,FGFR1,FOXG1,ANKFY1,SORBS1,PDLIM5,GAB1,MSL3,GNAS,STON1,HSF2,IL6ST,INPP5B,MIA2,ADAM22,MSR1,NFIX,KCTD15,PPP5C,PSMD13,RGS10,TMEM156,KBTBD4,BTBD7,SLN,SNCA,TMCC1,FNBP1,IZUMO4,SPTAN1,COBL,FBXW11,TMEM121,TMOD1,RUNDC3B,TRPC1,UBE3B,KAT6A" Drug 2029_UP Famotidine [76824-35-6]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADAR,ADORA3,KIDINS220,AK2,ALAD,ARRB2,N4BP2L1,BCL7A,NRP2,CA12,CAPN3,CHN2,CNOT8,FAM189A2,C2CD2,SPOCK2,HP1BP3,TMCC2,DLG3,BSCL2,DCTN4,CAMKK2,GLS,IRAK3,MAN1B1,ELOVL5,HNMT,MBNL1,GIT1,NF1,SETD4,ODF2,PPM1B,PTPRE,CCDC40,RAP1GAP,SUPT20H,ITSN1,FAM102A,AMBRA1,WDR47,KBTBD4,ELMO2,EMC1,LMO3,FCHO1,CEP68,SYT11,FBXW11,TBL1X,ARHGEF12,RBFOX2,TPM3,HIRA,NSD2,ZNF24,UPF3A" Drug 4761_UP Foliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "RALGAPA1,ASIC1,RASL11B,ATP2B3,LDLRAD4,CFAP410,RHBDL1,USP2,CDH2,CDH8,CDO1,ZFYVE9,SULT4A1,ARHGEF6,RCHY1,AATK,DAPK1,SPOCK2,ELAVL3,EPB41,MTSS1L,NRN1,PTK2B,TUBB4A,FGFR1,GPR153,FYN,GAP43,GSN,KLF12,KCNH1,KCNH2,KHK,VWA5A,AFDN,ADAM22,OMG,OPCML,GPR85,PFKFB2,PLPPR1,PTHLH,RAD52,DCUN1D2,MYH14,LIMS2,SLC8A1,ZNF415,HECW1,TROVE2,MAPK8IP3,AJAP1,SEMA4A,PCDHGA1,DOCK9,MVB12B,ST7" Drug 6009_DN Lansoprazole [103577-45-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "MRTFA,TRMT9B,AMT,FAM131A,ARRB1,PDE8B,SLC2A11,ALDH7A1,ADAM23,SYNJ2,CACNA1I,NEURL1,CRLF1,B4GALT6,CSF1R,CTNND2,SIDT2,PHF20L1,SUGP2,MBNL2,F3,FAM198B,KAT8,ZNF589,FHL1,TRAF3IP2,TXNL4A,MSL3,GNG4,TDRKH,CNTRL,GRM8,KCNC1,KHK,TM6SF1,TAGLN3,LRP12,PRPH,RET,RGS10,ANKRD6,ZNF365,PREX2,KDM4B,SPTAN1,SPART,TROVE2,EXOC7,IQCE,PSD3,CRTC1,TK2,RIMBP2,VGF,VIPR2,XRCC4,ZFP37" Drug 2349_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADGRF5,BEGAIN,APOC1,SEMA4G,ARRB1,CDK13,ALDH4A1,KIF1A,BMP7,CAMK2G,CPS1,SEC31B,FEZ1,VCAN,PDE4DIP,KIAA0753,SMG7,SGSM2,TMCC2,DTNA,SIDT2,MRNIP,COQ7,NCALD,F5,PRKAG2,GPR153,DLL3,SEPT9,GJB1,ELOVL5,INPP1,JAK2,MAP4,NELL2,NF1,NINJ2,NPR2,OCRL,OMG,NLE1,PLCD1,PPP2R5C,TMEM231,RALGDS,RET,RGS12,SAFB,CNKSR2,SLC15A2,KDM4C,DBNDD2,TSPYL2,SEPT8,VAMP1,PSD3,THBS4" Drug 4120_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "AMPD3,ARRB1,CDK13,N4BP2L1,USP2,CHRNB2,CLCN4,AKAP7,WHRN,NCOR2,RGS6,ATRNL1,CNTNAP2,RIMS2,DAPK1,DMPK,DYRK1A,EDNRA,TENM1,SPEG,GAB1,GAD1,RND1,GNG3,GUCY1A2,FAM107A,ATXN2L,SHISAL1,VWA5A,MMP17,MOBP,ADAM22,MX1,PDE1C,PFKFB2,LRP12,PPARA,RAB3A,RAB3IL1,RAD52,KCTD17,ZFP2,PPP1R9A,SLC6A9,CCDC88A,SLC11A1,SOX2,PEG10,ATP10B,AJAP1,KIAA1107,TEX15,TPM1,TRPC1,SLC30A3,SSPN,AP3B2" Drug 388_DN raloxifene hydrochloride; Down 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "RALGAPA1,BRAP,ANK1,APOC1,AQP4,CADM3,RAB29,BTRC,CACNA1D,MAP7,RUNX1T1,CD86,CDC42,CACNA2D2,TAOK2,SLIT2,NIPBL,RGS6,KLHL3,DLG3,SUGP2,RCAN2,ERBB2,EFS,TUBB4A,IQCG,CINP,FAM49B,SEPT9,HTATSF1,HMX1,ICA1,KCNA1,KCNJ5,MAP4,NOVA1,OMG,PCSK5,PDE4B,CCSER2,MED1,VPS13C,PLEKHB2,RALGDS,RGS12,RLBP1,ZFP30,SH3BP2,SMTN,GANAB,TBL1X,GPR161,TMPRSS5,KLC2,LMAN2L,MPPE1,NUP214" Drug 2274_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "GAS7,CALB1,CBFA2T2,CDC42,CDH2,ASIC3,CHRNA4,CPS1,NCOR2,CSF1R,SPOCK2,CTIF,MAGI2,HEYL,ELAVL4,ERCC2,ANKMY1,REEP2,HBS1L,NEU3,GNAO1,GRIN1,GRIN2C,GRM8,PTGDR2,HLF,VSIG4,IGF1,KCNJ5,MAOB,MN1,MX1,NF1,NTRK2,PCSK2,WDR25,PTAFR,PTCH1,PLPPR1,C1orf54,NUDT11,RORB,SCNN1D,ASAP3,SLC2A5,SPP1,NPAS3,PHLDB1,SYT5,TAC3,ZEB1,PSD3,TEX15,GPR161,TLR4,LAT2,SLC17A7" Drug 3325_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "BRAP,GRAMD1B,BIN1,CADM3,RGS11,CACNA1I,CFAP410,CACNA1D,RUNX1T1,CHN2,AKAP7,NECTIN3,SNCAIP,SRGAP3,NTM,HIPK3,ELAVL3,FHL1,HPCAL4,LYVE1,RUNDC3A,GNAL,GPER1,GRM1,GRM8,SCRG1,ICA1,TJAP1,KCNN1,MDM4,MMP16,NEK1,NEUROD1,NF1,SLC11A2,OMG,PAX6,PCDH9,PDE3B,STRN3,LRP12,SAMD9,ZMAT4,RGS4,FOXRED2,ZNF821,FRMPD1,SLN,LIMCH1,DOK5,ARHGAP26,MAPK8IP3,ANKRD12,WSCD1,TEX15,TNFRSF1B,KCNAB1" Drug 1203_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "STX16,ATP2B2,ATP6V0A1,KSR1,SCAPER,CACNA1I,CFAP410,CAST,EPS15L1,RAB28,CLCN4,QKI,ENTPD4,CSF1R,MFAP3L,TMCC2,CDON,CNNM1,ING4,MRNIP,PLEKHO1,FGFR1,SEMA4D,PDLIM5,PRELID3A,FYN,GNAL,CACFD1,RNFT2,ICA1,SHISAL1,IL6ST,LYRM9,NTRK2,PDGFRA,PRKAR1B,CNTLN,PTAFR,PTN,ZSCAN32,PTPRE,SEMA6D,CSRNP3,SLC4A3,SLC1A7,PEX26,SHANK2,IQSEC2,LHPP,TAB2,ZMYND8,HIRA,WIPF1,SH3GLB2,WNK1,PHTF2,NUP214" Drug 5391_DN Chlorpropamide [94-20-2]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASPHD1,SLC12A5,KIDINS220,APBB2,APP,CDK10,ARHGEF2,CLGN,SRSF11,NMT2,IQCK,BAG4,CRY2,DBN1,DBT,DTNA,EFNA3,MBNL2,PLEKHO1,KAT8,FER,PDLIM5,GCNT2,RUNDC3A,GNG4,EML4,MUM1,ATXN2L,ELOVL5,AGFG1,INPP5B,KIF2A,KITLG,NUMA1,LRP12,FSD1,PRODH,RGS12,NEK11,SEC14L1,SUPT20H,SH3BP2,FBXO11,ANKRD6,SLC1A7,KIF13A,RBM34,UNC5B,TROVE2,ST5,INKA2,TTBK2,PLCB1,SLC44A1,TK2,TPM1,MAP3K12" Drug 208_UP SC-58125; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADD3,BRAP,CDC42BPA,ANK1,APAF1,DGKD,CACNA1I,HAP1,CCNT1,CBFA2T2,ARHGAP33,FOXN3,CHI3L2,AKAP12,NCOR2,SPOCK2,ING4,C1orf61,SMC2,CSPG5,MALT1,GLYR1,GRIN1,NR3C1,HMX1,C2orf72,IL6ST,KCNJ5,KIF2A,ADAM22,SETD4,ODF2,OPRL1,PDE1C,GPR173,PLEC,PMP22,MAPK3,PRPH,PYGM,RIPOR1,C1orf54,FOXRED2,SAFB,KBTBD4,ELMO2,SYT5,ATP11A,WWC1,EHBP1,TCF7,PCDHA5,SEZ6L,ZKSCAN5,SF1,MAP3K12,MPPE1" Drug 6163_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ABAT,ASPHD1,PLA2G6,BCAS1,CDK10,SLC4A4,AZGP1,BTRC,NDST3,AKAP6,DAPK3,SPOCK2,DLG3,ATN1,EEF1A2,HEYL,ELAVL4,MRNIP,VPS13B,RASGRP2,ETV1,FGFR1,KHDRBS3,GAD2,GSTM5,AP4S1,KLF12,HNMT,KCNJ5,CD200,SAMD14,OPCML,RETREG1,CNNM2,PTCH1,MARCH1,CEP97,SYNDIG1,SCG5,SH3BGR,SH3BP2,PPM1E,SOX10,ZHX3,ZSWIM8,CAND2,IQSEC2,SEPT8,SEZ6L,TRPS1,ZMYND8,UBE3A,VSNL1,KCNK12,PRDM10,KCNAB1,CAB39L" Drug 2099_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "MRTFA,STX16,MTMR3,CACNG1,SLC16A4,SCARB1,QKI,ARMC8,CSF1R,SLITRK5,DCAF4,TOX,FCF1,PLEKHO1,MTSS1L,SEMA4D,EFCAB2,POLL,ATXN2L,INPP5B,KIF5C,LMO2,MMP16,MPP2,NF1,CNOT4,NOVA1,NOVA2,PALM,PCDH9,LRRN3,MAPK7,PRPH,ELOVL2,PTPRN2,SUSD4,GAL3ST4,RGS10,KCTD17,RPS6KA2,ZFP30,ASAP3,ARHGEF40,CCDC88A,SLN,FNBP1,SPTB,ZBTB43,VAMP1,TBL1X,GPR161,CABIN1,TRO,ZMYND8,LMF1,LAT2,ZIC3" Drug 4079_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "LTBP4,APP,BRINP2,N4BP2L1,ADAM23,NRP2,HAP1,RGN,GPR37L1,CHN2,CLCN4,STOML1,PCYT1B,CSF1R,RIMS2,DTNA,DTNB,EDNRB,REEP2,DCTN2,ATP8A2,GPR75,GNG3,GNG4,CACFD1,PTGDR2,HNMT,KCNJ3,KHK,LAMA2,MAG,MAN2A2,MYL3,NF1,PBX1,PCDH9,PDE4D,PLXNB1,PPP1R1A,DCHS2,RGS12,KCTD17,TMEM206,SCN2A,SCN3A,NTNG1,PKNOX2,SNCA,TNIK,ZC3H13,ARHGAP26,ATP11A,TMPO,KCNK12,ZNF74,NDRG4,PHTF2" Drug 4489_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "SEMA7A,APAF1,APBB2,APC,BCAS1,AQP4,CDK13,BRINP2,ATM,ATP6V0A1,CFLAR,FUBP1,CACNG1,CDH8,STOML1,HOMER3,AKAP6,TCEAL2,NCOR2,ABCG1,SEC14L5,CHRDL1,EXOG,EGFR,COQ7,ZNF391,SCML2,ST3GAL6,C1orf61,SPACA9,GRIN1,GRM7,PADI2,KCNJ5,MSR1,NTRK2,NTRK3,PDE1C,PFKFB2,STRN3,MINDY2,PTCH1,ZSCAN32,PTPRD,C1orf54,RET,TCP11L1,FBXO11,PKNOX2,SYT11,PLCB1,TACR1,MCF2L,WWC1,RALYL,SPHK2,KCNAB1" Drug 3329_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ARID1A,NDRG2,NME5,AMH,AMPD3,CDC42BPA,GAS7,CDC14B,MARK4,N4BP2L1,CFAP410,PICK1,AKAP7,NECTIN3,SNCAIP,RIMS2,CTIF,DCT,GSDME,CNNM1,EFNB3,C3orf18,DMTN,ERCC2,PIPOX,OLFM1,FGF13,C1orf61,DCTN2,EFCAB2,GAD1,ADAMTS13,GSTM5,HLF,IL6R,KCNJ5,MAPT,MEF2C,AFDN,MMP17,NF1,PDE4D,PFKFB2,KLHDC8A,EMID1,SYNDIG1,ITSN1,PPP1R9A,PREX2,FAM214B,KDM4B,ZNF423,ATP10B,AJAP1,JMJD6,TBCEL,GPR161" Drug 6347_UP Isradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ACTN2,AGT,DOC2A,BIN1,EPB41L5,PPP4R4,CFLAR,BAIAP3,RUNX1T1,SLC24A2,LY86,AKAP7,IFFO1,PDE4DIP,SMG7,ATN1,SIDT2,EGFR,PLEKHO1,FGF1,FOXG1,FOXF2,TRMO,OGA,SEPT9,NEU3,GLYR1,KCNF1,KCNMA1,LIG4,ENPP2,DUSP26,CCSER2,POU6F1,PPARA,RASGRF1,GAL3ST4,RGS4,TCP11L1,SALL1,IL17RB,ZNF821,ITSN1,SLC1A7,KANSL3,BTBD7,SLCO1A2,SMARCD3,KDM4C,SPTB,IQSEC2,TEX15,AP4E1,TNS1,HIRA,WNK1,DPF3" Drug 4706_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ABHD6,NDRG2,ADGRB3,NRP2,LY86,BAG4,CSF1,RGS6,RIMS2,GIT2,DBT,MAGI2,DRD1,ATN1,EFNB3,EIF4G2,RRAGB,FGF12,FGFR1,AFF2,ZMYND11,LYVE1,HPGDS,GLYR1,RAPGEF1,KCNJ3,LIG4,SMAD1,MBD1,MID1,NOVA2,P2RY1,CDK18,SERPINI1,LRP12,TNPO2,PPP5C,PRODH,PTHLH,RAD52,RASGRF1,NLGN1,SNCA,TAL1,DMXL2,PCDHGB6,PCDHA6,DICER1,TNS1,CDK20,UBE3A,WIPF1,WNK1,NT5M,SLC17A7,SSPN,JPH3" Drug 3788_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "SYN3,ADORA3,FAM135A,AMT,ANK1,APBB1,APC,AQP6,ARRB1,ATP6V0A1,ADGRB2,GYG2,CACNA1A,CACNA2D1,CDO1,SLC22A6,PCYT1B,SH2B1,SPOCK2,CHRDL1,SGK2,SIDT2,ELAVL3,EXTL1,REEP2,TOX3,POLL,PRUNE2,GPM6A,GRM7,GUCY1A2,WIF1,KCNF1,KCNJ4,KCNJ5,KCNN2,VWA5A,MGAT3,MMP17,GIT1,SAMD14,P2RY13,NCAM2,NF1,FXYD1,POU3F2,PROX1,SLC8A1,SLC15A2,ZNF667,KIF13A,MAPK8IP3,TUBB1,VAV1,LAT2,SLC17A7,DPF3" Drug 4783_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADD2,FZD9,KCNAB2,FAM131A,ATM,ATP6V0A1,FGF17,CFLAR,SYNJ1,SYNJ2,CFAP410,CACNG1,CD86,CHN2,CHRNA4,RAB33A,WHRN,RASSF2,TENM1,EPHB1,ACSL4,KAT8,FGF13,FGFR1,FHL1,AFF2,GPM6A,GPM6B,GRM8,AP4S1,GUCY1A2,ICA1,ITIH2,KCND3,KCNMA1,VWA5A,MPP2,TAGLN3,CNOT4,NPPA,SERPINI1,PLTP,ROM1,FRMPD1,PKNOX2,STX1A,WSCD1,TRIM2,PCDHGA1,TEX15,TGFBR3,TMOD1,CABIN1,WIPF1,ETNPPL,GDPD5,RNF146" Drug 2839_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "NDRG2,LTBP4,BIN1,APBB2,APOC1,CDK10,SLC2A11,BMP7,CACNG1,CDH2,ADGRG1,ZFYVE9,WHRN,PPP6R2,SPOCK2,MFAP3L,RABGAP1L,DTNB,C3orf18,VPS13B,FGFR1,CAMSAP1,GAB1,GABRG2,SIGLEC8,SRCAP,MSL3,GNAS,GPR37,CACFD1,NR3C1,GSN,IL6ST,INPP5B,KCNH2,MAOB,MITF,MYO9A,NF1,NUMA1,PGAM2,MED1,RGS12,PPP1R9A,FRMPD1,ASAP3,SHANK2,SLC20A2,SLN,LIMCH1,SOX3,ARHGAP26,POPDC3,DICER1,PIK3R5,VLDLR,KCNAB1" Drug 7138_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "MTUS1,C1QTNF1,BIN1,APBB2,APP,CDK13,BMP7,ARHGEF7,KYAT1,SCARB1,ARHGEF2,LHX2,ZFYVE9,DNAJB5,HOMER3,CREM,MICAL2,SPOCK3,HIPK3,EFNA3,ING4,PLEKHO1,TRMO,CINP,TMEM8B,MSL3,GNAS,CNTRL,GUCY1B1,RASSF8,SYNPO,INPP5B,SCAMP5,ZNF862,NASP,NF1,NPR2,PLCD1,MINDY2,MAPK7,PRPH,PTN,RGS10,DZIP1,PEX26,FAM214B,SLC20A2,SNCA,DOP1A,PDLIM2,DOCK9,CRTC1,NSD2,ZBTB14,ZNF711,WNK1,MPPE1" Drug 3895_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASIC1,MRTFA,APP,SCAPER,CFAP410,CACNA1D,CAMK2B,CAMK2G,KYAT1,PLEKHB1,B4GALT6,FADS2,PICK1,WHRN,NECTIN3,SH2B1,CRY2,NCOR2,SOCS5,GPRASP1,ZNF804A,DMPK,DRD1,KAT8,ZNF589,DISC1,SRCAP,GHR,RUNDC3A,STON1,IGSF1,IL6ST,ITPKB,MMP16,MMP17,ADAM22,BCO1,ZNF862,NDUFA5,NF1,NPPA,CCDC40,RAD52,PPP1R9A,LIMCH1,IQSEC2,VPS13A,ARHGEF12,AHCYL2,TGFBR3,SLC44A1,THRA,PARD3,PLPPR2,VIPR2,SYNC,SSPN" Drug 6378_DN valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "DPF1,ADCY6,APBB2,PPP4R4,SLC2A11,GYG2,MYRF,CACNA1D,THSD7A,CBFA2T2,ARMC8,ERC2,DCAF4,GPRASP1,TOX,RUSC2,C2CD2L,DSCAM,DTNA,USH1C,FRY,MBNL2,PLXNC1,MTSS1L,TESK2,FGF1,ERAP1,CPLX2,RUNDC3A,RND1,HSD17B1,ITIH2,KCND3,MGAT3,NTRK2,GPR85,CNTLN,ZSCAN2,C1orf54,RGS10,ZNF671,PAQR6,RYR1,FBXO11,SLC11A1,RIMS1,MAPK8IP3,ASTN2,TCF4,TK2,TRPC3,RPRM,FLRT2,SPHK2,REEP1,PHTF2,DPF3" Drug 2498_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADRA1D,AP2A2,BIN1,APAF1,APBB2,CASK,SLC4A4,N4BP2L1,RUNX1T1,PLAA,CNTN1,AKAP7,IQCK,SH2B1,ABCG1,DGKG,CTIF,TRAPPC9,CELSR3,EIF4G2,SORBS3,CDKL3,CEND1,F5,PTK2B,ST3GAL6,KAT8,GABRA2,USP19,GPM6B,PADI2,TJAP1,ZNF862,NUMA1,ST8SIA5,PLCD1,NECAB2,POU6F1,PTPRN2,PEX5,RAB3A,MYH14,ZNF821,SH3BGR,PEX26,ARHGEF9,SYN2,EXOC7,PDLIM2,ADGRL3,KIAA1107,CHST8,ZNF34,THBS4,FLRT1,FZD3,UBE3B" Drug 5464_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "NME5,KCNAB2,PPP4R4,ARHGDIG,ASPH,ASTN1,FGF17,CDK5R1,ARHGEF1,ARHGAP33,RCBTB2,CLCN4,SULT4A1,VCAN,TOX,GIT2,JAKMIP2,KIAA0753,DUSP9,PLXNC1,DMTN,ACSL4,TPK1,GAD2,DISC1,GATM,RUNDC3A,GSN,HPSE2,HNMT,TJAP1,IGSF1,IL11RA,KCNH2,KCNMA1,LIG4,FAM120C,C1orf54,ZNF493,RGS4,TMEM100,TCP11L1,RPS6KA2,ZNF821,COA1,SNCA,FAIM2,ATP11A,TACR1,MCF2L,SMG6,KIAA0930,PCDHGA1,DOCK9,PIK3R5,SEZ6L,CLDND1" Drug 3695_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "APAF1,BCAS1,ATP2B2,ADAM23,KSR1,BMP7,LDB2,CBARP,SLC22A6,NRXN3,RCHY1,EDRF1,EFNB3,EGFR,EPHA5,EPHB1,CEND1,F5,HPCAL4,ZNF44,ALDH1L1,C1QL1,RUNDC3A,GRIA4,GRM2,LSS,NOS1,PAK3,PBX1,FXYD1,MAPK8,PTPRB,ZSCAN2,RALGDS,SUSD4,GAL3ST4,RFX2,RGS4,CARF,ASIC4,CPEB3,SLITRK3,SOX3,TNIK,IZUMO4,MLC1,ATP11A,KAZN,SMG6,PCDHGA10,TK2,TNS1,FLRT2,ZIC3,SPHK2,SLC17A7,EPM2A" Drug 343_UP HA-1077 dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "CDC42BPA,APBB2,GAS7,KALRN,AP4M1,SOCS6,CHRM4,CNR1,ENTPD4,HINFP,EXOG,HIPK3,FEM1B,SIDT2,MBNL2,EGR3,ELAVL4,SPEG,EFEMP1,FGFR1,BAIAP2,SEC23B,FLNC,GLYR1,GNAS,GRIK5,IL6ST,BRINP3,IPO5,MYL3,NACA,NAP1L1,NF1,NOVA1,NTRK2,SETD4,OGG1,PPM1B,MAPK8,MAPK10,MTMR10,ARHGEF10L,SH3BP2,SLA,KBTBD4,SLC15A2,ELMO2,SON,SEPT8,POPDC3,TRIM2,PHF24,TMPO,METTL3,ZKSCAN5,WIPF1,LAMP5" Drug 7190_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "PLA2G6,FAM131A,ALDH4A1,ATM,CFLAR,SCAPER,CAMK2G,ARHGEF2,SOCS6,RAB28,NMT2,FAM189A2,QKI,FEZ1,EDRF1,ZNF337,MFAP3L,HIPK3,EFNA3,MBNL2,COQ7,BAIAP2,SEMA4D,ANKFY1,PDLIM5,DLL3,SRCAP,RUNDC3A,GLYR1,GRB10,GRM7,IL6ST,INPP1,MAPT,TAGLN3,PDE3B,PDE4D,MINDY2,PRPH,RGR,SYBU,PPP4R3A,SLC22A4,ZKSCAN3,CAND2,SS18,MAPK8IP3,VAMP1,SEMA4A,EXOC7,PCDHA6,THRA,SEZ6L,SLC13A3,ZNF45,EVI5,MVB12B" Drug 3174_UP Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ARID1A,AMPD3,CDC14B,ARHGDIG,CCDC181,ATP2B2,NEURL1,B4GALT6,SLIT2,CSF1,HDAC4,NTM,DPP6,CALCRL,EPHA5,ETV1,F5,FHL1,C1orf61,CHL1,ATP8A2,PCDH17,GPD2,TDRKH,GRM8,GSN,VWA5A,MEF2C,AFF1,AFDN,MSR1,NCF2,PCBP3,PDE3B,RETREG1,PLTP,MAPK7,MAPK10,PROX1,RGS12,KCTD17,TTLL7,PREX2,SLC9A5,SHANK2,SNAP25,MYT1L,SP4,CDK19,NPAS3,ATP10B,PHLDB1,WIPF1,ZIC3,ZNF45,NT5M,NLRP3" Drug 4432_UP "estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "TTYH1,KLRC4,ADRA1D,NLGN4X,SEMA7A,GAS7,CDC14B,MARK4,KSR1,CDK5R2,CFAP410,CA8,CA12,KALRN,LDB2,CHRNB2,RAB33A,TPP1,PDE4DIP,DCT,ATN1,DTNB,ST8SIA3,ELN,OLIG2,EFS,CDHR1,CORO2B,NSG1,RUNDC3A,GPR37,HRH3,HTR2A,IRF8,ITGA7,MAN2A2,MATK,MGAT3,MYH6,NTRK3,ENPP2,PGAM2,PIK3R1,PPP5C,PTPRN2,RNASEL,PKNOX2,ZNF334,RIMS1,SP4,MCF2L,PCDHGA10,TK2,TNS1,UCHL1,VIPR2,ZNF225" Drug 5435_UP Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ACTN2,BIN1,APBA2,GAS7,SEMA4G,RASL11B,ATP2B2,CADM3,RGS11,ST3GAL5,LDLRAD4,HIP1R,CDH8,ADGRG1,STOML1,CPS1,RIMS3,SPOCK2,DCC,JAKMIP2,DRD1,DUSP9,HIPK3,CEND1,AFF2,RND1,GLS,GRIK5,SHISAL1,KCNB1,KCND2,KCNQ3,MBP,PCSK2,PDE4D,PILRA,WDR25,MTMR10,RAD52,RGS12,SALL1,TRIM46,FAM214B,WDTC1,SOX2,HECW1,IQSEC2,TCF4,TNS2,CRTC1,ICAM5,TRIO,VAV2,ZIC3,KCNAB1,ITM2C,TIGD6" Drug 4435_DN retinoic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "PLA2G6,C1QTNF3,APBB2,MPDZ,BTRC,ARHGAP33,FOXN3,KIAA1549L,CLU,HINFP,AATK,PDE4DIP,DAPK3,PLXNC1,NCALD,SCML2,PRELID3A,PNMA2,B4GALNT1,ERAP1,COPS8,POLL,KCNMB4,STON1,HSF2,ICA1,SCIN,MEF2C,PFKFB4,PIK3R1,MINDY2,CNNM2,GON4L,WDR25,CNTLN,RAB3IL1,RAD52,KIRREL1,RPS6KA2,ATXN7,BCAN,DZIP1,ARHGEF40,SMARCD3,MYH15,SNCA,EMC1,COLGALT2,MAPK8IP3,SEMA4A,CHST8,TMPO,FAM155A,UGT8,PARP6,SEMA3B,NAV3" Drug 6356_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "SYN3,ARRB2,ATP2B2,CFLAR,SYNJ2,NMT2,ABCG2,DNAJB5,SULT4A1,AKAP5,PDE4DIP,DTNA,EDIL3,EDN1,FAM13A,MBNL2,TUBB4A,OGA,FYB1,GAP43,PCDH17,GLYR1,KCNMB4,PRRC2B,GRIN1,RASSF8,IL6ST,ITGA7,KIF5A,MAPT,TM6SF1,MIA2,NF1,CNOT4,NUCB1,NUMA1,ENPP2,NECAB2,MAPK8,GON4L,PREX2,SLC2A5,SLC6A9,IFT122,CDK19,ZBTB43,PHLDB1,ADGRL3,KLHL4,TRIM2,ATP13A2,ZFPM2,TRIO,NT5M,HRASLS,TIGD6,DPF3" Drug 5814_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASPHD1,ACTN1,PLA2G6,C1QTNF3,AMPD3,GAS7,KIF1A,CFLAR,CHGA,CHD1L,VCAN,PDE4DIP,ARHGAP24,DCAF8,ZNF337,TM9SF4,CTIF,GIT2,KIAA0753,C2CD2L,DTNA,OPTN,AASS,MRNIP,FGFR3,FYN,LPAR4,SPACA9,GRIK5,PADI2,KLF12,HSF2,IRF8,KCNMA1,MIA2,CD200,TAGLN3,ODF2,PBX1,RC3H2,SPATA6,PRODH,RAB3IL1,RAD52,MYH14,SBF1,CSRNP3,ZNF334,ZHX3,KDM4C,INKA2,ELOVL4,TBCEL,TRIM2,TMEM151B,TK2,NT5M" Drug 2302_DN Ofloxacin [82419-36-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "AMPD3,APOC1,HAP1,CAMK2G,MAP7,CNOT8,SLIT2,TPP1,FAM189A2,DNAJB5,SLC4A7,TBC1D5,HP1BP3,F3,ACSL4,FOXG1,SEMA4D,SEPT9,POLL,GNG4,BTN2A1,ATXN2L,INPP5B,LIG4,LMO2,MATK,NEK1,NF1,SETD4,PALM,STRN3,ELOVL2,RAB3A,TRIM68,RGS10,FBXW7,TCP11L1,MAPK12,SH3BP2,FNDC3A,ZNF365,PPP4R3A,EPN2,SHANK2,SLC20A2,SLN,ZCCHC24,EMC1,KDM4C,IQSEC2,ST5,ELOVL4,PLCB1,EXOC7,KIAA1107,ZNF45,RNF170" Drug 4363_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "C1QTNF1,BIN1,SEMA7A,PRX,SCAPER,CACNB2,CCKBR,GPR37L1,SULT4A1,DGKG,SV2A,ATN1,ST8SIA3,ELAVL3,OLIG2,ANKMY1,REEP2,FYB1,ERAP1,ALDH1L1,GPR162,RUNDC3A,GRM1,CELF3,KCNB1,KIF5A,MGAT3,MOBP,CD200,ADAM22,TAGLN3,MYT1,CNOT4,NTRK3,KCNK10,PLCB2,PPP2R2B,PRKCB,GDPD2,CCDC40,SATB1,MRAS,RPH3A,SLC1A7,SLC6A9,MYH15,RIMS1,ZC4H2,SYT11,VAMP1,TACR1,WSCD1,PCDHGA1,R3HDM1,LAT2,LAMP5,PLSCR4" Drug 6965_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "TRMT9B,BCAS1,ARRB1,GYG2,LDLRAD4,BTRC,COL9A3,PDE4DIP,KIAA0513,ZNF804A,SRGAP3,DMPK,TRAPPC9,DTNA,SIDT2,ENO2,MTSS1L,ST3GAL6,FHL1,C1orf61,FYB1,GCNT2,GNAS,GNG3,STON1,LPAR4,GPR37,SPACA9,HLF,KCND3,KCNJ3,MAP4,MAPT,MBD1,AFDN,PCDH9,PPP2R5C,MAPK8,PRPH,PTX3,PAQR6,PREX2,PKNOX2,BTBD7,STX1A,ACSBG1,IQCE,TRIM2,TK2,TPM1,RUNDC3B,LMF1,KCNK12,TFIP11,GDPD5,NUP214,SSPN" Drug 4345_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ALCAM,APOC1,ASCL1,ASPH,PROM1,CFAP410,CDH2,RCBTB2,VCAN,NOS1AP,DAPK1,CTIF,ARMCX2,DTNA,SGK2,FRY,C3orf18,EN2,CACNG3,NSG1,CSDC2,GNAL,GRM3,GRM7,HLF,ELOVL5,C2orf72,ITGAM,KCNB1,KCNH2,LAMA2,MOBP,NOVA2,P2RY1,CDK18,TMOD2,PGAM2,PIK3CD,MAPK7,PTAFR,PTH1R,RASGRF1,SH3BP2,CNKSR2,RPH3A,ZCCHC24,HECW1,ZNF423,TBCEL,R3HDM1,SEZ6L,LAT2,SCG2,SLC17A7,PLSCR4,NLRP3,DPF3" Drug 5422_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ARID1A,PLA2G6,SPARCL1,LTBP4,MRTFA,ASPH,MPDZ,CFLAR,ST3GAL5,SLC16A4,ARHGEF1,ARHGAP33,CLGN,ABI3BP,USP6NL,ELMO1,CNIH3,DTNA,EDNRA,EFNB3,COQ7,DENND4A,FHL1,AGAP2,STAG2,TMEM8B,ALDH1L1,GRB10,KCNH2,KCNN1,KIT,MAOB,TAGLN3,MYO7A,SLCO1C1,NTRK2,PDE3B,PENK,POLG,PTAFR,PTHLH,FAT4,RFX2,SATB1,FBXO11,SLC2A5,SLC11A1,SHANK2,ZCCHC24,RGL1,POPDC3,ANKRD12,DMXL2,TMOD1,SYNC,WNK1,DNALI1" Drug 4074_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ALDH7A1,CLCN4,NMT2,HOMER3,CPS1,CREM,VCAN,GPRASP1,CHRDL1,DYNC1I1,ATN1,SEZ6L2,EDNRA,EFNA3,PLEKHO1,FGF13,ZNF44,GAD1,DISC1,INPP5K,ZNF276,TDRKH,SHISAL1,RBPJ,KIF5C,MAPT,MPP2,NASP,NOVA1,NUMA1,CDK14,PIK3R1,SLC25A23,LRP12,MAPK7,RIPOR1,RGS7,TRAPPC13,TMEM156,ITSN1,FNDC3A,PPP4R3A,KBTBD4,EMC1,SS18,MAPK8IP3,VAMP1,KAZN,ZEB1,ARHGEF12,TK2,TNS1,OSBP2,LMF1,XRCC4,ZNF45,NAV3" Drug 6384_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADCY2,ADORA2A,SYT13,MRTFA,CDC42BPA,APC,NEURL1,SLC22A6,AKAP7,CTH,FAM131B,SHANK1,ERCC2,IGSF6,PTK2B,FGF1,BAIAP2,SCARA3,AGAP2,DPYSL4,FUT9,POLL,GNAL,GRIK5,CELF3,SYNPO,HNMT,ICA1,L1CAM,LIG4,MGAT3,AFDN,MMP16,ADAM22,CLDN11,PAX6,MTRF1L,POU3F2,RELN,ZSCAN2,RAD52,ZNF493,TCP11L1,SATB1,ZNF423,MAPK8IP3,SUPT5H,ARC,TCF7L2,SYNE1,PIK3R5,TRO,WIPF1,ZIC3,SPHK2,PLSCR4,NUP214" Drug 2867_UP Triflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASIC2,AP2A2,BIN1,APAF1,DNAH17,PROM1,CFAP410,CALB2,CDH8,GPR37L1,TPP1,CRMP1,SPOCK2,MAGI2,DLG2,CDON,ATN1,DYRK1A,OPTN,PLXNC1,ERBB2,ETV1,FGF12,GAB1,SIGLEC8,NEU3,HPGDS,HTR2A,KCNJ5,MSR1,NEUROD1,NF1,SLCO1C1,CNOT4,NPPA,NPTX2,NUMA1,TREM2,TMOD2,SERPINE2,CEP41,DIRAS2,RAD52,RTN1,SLC30A10,ITSN1,PKNOX2,SNCA,WDTC1,NPAS3,SYT11,VAMP1,ZEB1,DAAM2,TPM3,XRCC4,KCNAB1" Drug 2140_DN Seneciphylline [480-81-9]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "CDC42BPA,APC,FOXN3,RAB33A,CLTB,CREM,RIMS3,DGKG,C2CD2L,SGSM2,EXOG,TRAPPC9,ELN,RASGRP2,NCALD,VPS26C,ANKMY1,KAT8,KHDRBS3,ZNF44,ERAP1,WASF3,GLS,GNG4,GPD2,LILRA2,DIDO1,FICD,GIT1,MYT1,NF1,PLTP,PMP22,PTPA,MAPK8,TMEM231,RAB3IL1,RAD52,RET,ARHGEF10L,ZNF821,SCG5,PEX26,SLC11A1,ZKSCAN3,ZCCHC24,SP4,SS18,MLC1,PLCB1,TCF4,ZEB1,TMOD1,RBFOX2,UBTF,LMF1,PRDM2" Drug 2845_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ABHD6,NDRG2,ADCY6,AP2A2,NME5,KCNAB2,APBB2,APC,PPFIA3,PLA2G4C,ALDH4A1,CA4,CDC42,ADGRG1,CSF1R,CTH,ERCC2,TBC1D16,FGFR1,BAIAP2,GAD1,SRCAP,GNAS,GPM6B,GRM7,KLF12,INPP5B,KCNH2,SMAD1,MIA2,ADAM22,ZNF862,NF1,PALM,PCDH9,PFKFB2,LRP12,TNPO2,PPP5C,CEP41,MAPK7,RGS12,STUM,ASAP3,PEX26,SLC9A5,SOX3,TSNAXIP1,SZT2,ARHGEF12,DICER1,TK2,HEY2,NR2C2,ZKSCAN5,VAV2,GDPD5" Drug 5684_UP Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ADORA3,C1QTNF3,LTBP4,MRTFA,AQP4,ATP2B2,CACNB4,CALB1,MYOM2,WHRN,CPS1,CRY2,ATRNL1,PLCH2,PDE4DIP,EDRF1,SNPH,ARHGAP24,DGKB,GIT2,HS3ST2,SGK2,TENM1,TNK2,MRNIP,FHL1,GABRA2,GAD1,GAD2,TMEM8B,SRCAP,GPR162,LYVE1,GRIK1,NR3C1,BTN2A1,KIF5A,L1CAM,NF1,NFIX,P2RY1,STRN3,TCP11L1,RASA3,PKNOX2,SLC11A1,SHANK2,ARHGAP26,SYT11,SYN1,ZEB1,HIF3A,TRPC1,FLRT1,EMSY,SSPN,AP3B2" Drug 5114_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASIC1,NLGN4X,PLA2G6,LTBP4,EPB41L5,APLP1,BRINP2,NRP2,CHN2,WHRN,CDC42BPB,ENTPD4,SH2B1,HAPLN1,CRY2,FAM131B,SIRPA,SMG7,CHRDL1,TOM1,EDNRA,COQ7,NRN1,PDLIM5,GPR153,GBX2,CACFD1,ICA1,AFDN,MYCN,MYT1,NTRK2,RETREG1,MINDY2,MAPK7,CNNM2,TMEM231,FAT4,RASGRF1,RGS10,MYH14,RPS6KA2,ZNF821,FRMPD1,ASAP3,DZIP1,SLC4A3,ARHGAP26,DBNDD2,ZBTB43,COBL,ASTN2,SYT5,SZT2,ZNF34,CADM1,LAT2" Drug 481_DN WY-14643; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "RBM10,ADD2,MTUS1,KCNAB2,ARHGAP5,ARRB2,BMPR1B,CA12,CACNA2D1,KCNAB3,SRSF11,NDST3,LHX2,CLTB,NIPBL,ABI3BP,CRMP1,PDE4DIP,GIT2,HP1BP3,SMG7,AK5,SIDT2,EFNA3,EFNB3,EGFR,CORO2B,ST3GAL6,FCGRT,FOLR2,CAMKK2,NSG1,MAN2A2,MAPT,MGAT3,MT1M,MYH7,NACA,PLXNB1,C19orf57,PRKAR1B,MARCH1,WLS,CSRNP3,TNIK,FNBP1,SPTB,PLCB1,EXOC7,DOCK9,CRTC1,SEZ6L,VIPR2,SLC13A3,SPHK2,MAP3K12,MVB12B" Drug 3926_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "SYN3,ADORA1,ADRA1B,ADGRF5,BEGAIN,FGF17,DLGAP1,TCEAL2,CRY2,SNCAIP,DNAJC6,DNAH9,TRAPPC9,DYRK1A,ELAVL3,RCAN2,ERCC2,ZNF391,PTK2B,AFF2,FYN,CHL1,GFAP,GFER,HPGDS,GNAS,GRIK5,GRM7,SHISAL1,MMP16,MYCN,NEUROD1,PCBP3,CEP41,PTCH1,CCDC40,C1orf54,GAL3ST4,SYNDIG1,SATB1,SLC30A10,ZFP2,STUM,ASAP3,SLC1A7,CCDC88A,SNCA,NMNAT2,CLSTN2,COLGALT2,SSTR2,JMJD6,ATP11A,SEZ6L,TUBB1,VAV2,MVB12B" Drug 2154_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ACTN2,ADD2,NLGN4X,AGT,FAM135A,CDC42BPA,ANK3,SEMA4G,PDXK,AZGP1,CACNA1I,CACNG1,REPS2,CREM,CSF1,VCAN,SPOCK2,SV2B,CNNM1,EFNA3,EGR3,CALCRL,EIF1,GFER,C1QL1,ZNF276,ATF7,GUCY1A1,ICA1,MAP4,AFF1,CD200,LYRM9,ZNF862,NNAT,NPPA,ENPP2,EPN1,MTRF1L,FSD1,PRKAR1B,PTPN13,PTPRB,RIPOR1,ZCWPW1,GAL3ST4,PLPPR3,SMTN,SLC9A5,PHLDB1,SYN2,ADGRL3,WWC1,CRTC1,SLC35G2,RUNDC3B,FLRT1" Drug 4595_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "MRTFA,PKP4,CDK10,MARK4,NRP2,CACNB2,TPP1,HOMER3,COL9A2,ENTPD4,CSF1R,CTIF,SGSM2,EDNRA,IRAK4,ING4,MRNIP,F3,TUBB4A,FGFR1,SCARA3,CINP,FYB1,INPP5K,GLYR1,TDRKH,STON1,ATXN2L,SHISAL1,MAPT,MMP16,ZNF862,ODF2,CLDN11,PLCD1,RAB3IL1,RAD51D,RAD52,RAP1GAP,GAL3ST4,DCUN1D2,ZNF821,PPP1R9A,DZIP1,ANKRD6,PEX26,ZNF667,ZHX3,MAPK8IP3,VAMP1,ASTN2,GPR161,TK2,VGF,WIPF1,TFIP11,MAP3K12" Drug 3527_UP Iopanoic acid [96-83-3]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "BRAP,APLP1,SCAPER,CACNA1I,BAIAP3,ARHGAP33,CACNA2D2,FOXN3,PLEKHB1,NRXN1,SLC4A7,RCHY1,VCAN,SOCS5,PHF14,GREB1,SEC14L5,DUSP9,DYRK1A,FCF1,VPS13B,ANKMY1,DLC1,ST3GAL6,FGFR1,FOXG1,TMEM8B,MALT1,LYVE1,RND1,SOX21,ICA1,LIG4,AFF1,ADAM22,MSR1,PACSIN1,PPP2R2B,PPP5C,GRAMD1C,RGS12,TTLL7,TCP11L1,TRA2B,RAB3GAP1,CXXC4,SYT5,KAZN,SZT2,DOCK9,R3HDM1,AMACR,XRCC4,ZFP37,STMN4,MVB12B,TIGD6" Drug 368_DN WY-14643; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "BIN1,CNTNAP1,APBB1,SEMA4G,EIF4G3,ADAM23,CCKBR,DLGAP1,LHX2,KIAA1549L,SLC24A2,CPS1,CRHBP,ECE2,KLHL3,SRGAP3,RCAN1,ABCC9,FAM13A,EGFR,SORBS3,PLEKHA1,CALCRL,ZMYND10,SCARA3,HPCAL4,NSG1,GAB1,DENND2A,PCDH17,LILRA2,ADAMTS6,NXPH3,VSIG4,SYNPO,MMP16,ADAM22,CTNNA3,CAMKV,SDK2,SPATA6,PPP2R2B,LRRN3,CEP41,RNASE1,ITSN1,SH3GL3,ST6GAL1,SLC1A2,ZNF430,SLC11A1,SNAP25,POPDC3,SZT2,CDH22,SEZ6L,TRPM2" Drug 4395_UP Cyanocobalamin [68-19-9]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "DPF1,NDRG2,ADRA1B,ADGRF5,APBA2,CDC14B,ARHGDIG,GYG2,BAIAP3,CAMK2B,TAOK2,SLC22A6,CRYM,CSF1,VCAN,PDE4DIP,KIAA0319,DMPK,EIF4G2,TNK2,PIPOX,PTK2B,DLC1,SCARA3,FYN,RUNDC3A,ADAMTS13,GSTM5,HRH3,KCNB1,KCNJ4,VWA5A,CD200,NCF2,NOVA1,OPRL1,CDK18,SAMD9,RAD52,RGS3,TTLL7,SLC1A2,ARHGEF40,SLCO1A2,MLC1,TACR1,PCDHGA1,DICER1,TNS1,TTPA,FAM155A,OSBP2,FLRT1,LAMP5,SLC30A3,PRDM2,ITM2C" Drug 7544_UP CP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "ASIC2,ASIC1,AP2A2,BMP7,CACNB4,CDH18,VAX2,IQCK,WHRN,SDC3,TBC1D5,GIT2,PARD6A,DTNA,APH1A,C1orf61,AGAP2,AFF2,GPR153,DISC1,RAB30,ACOT7,INPP1,LMO2,LSS,MBD1,ZNF862,CNOT4,PDE3B,RETREG1,MBOAT7,RAB3IL1,ZCWPW1,ZDHHC14,MYH14,UEVLD,EMID1,FBXO11,EMC1,KDM4C,MAPK8IP3,STX1A,KAZN,EXOC7,WSCD1,CUX2,TRIM2,TK2,RBFOX2,CDK20,METTL3,LMF1,REEP1,SLC30A3,STMN4,UBE3B,RNF170" Drug 5644_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "NDRG2,MRTFA,FGD2,CDC14B,PRX,RGS20,CDK13,ATP1A2,CA4,CACNB4,ARHGEF1,CPS1,CREM,CHD5,DZIP3,PHF14,ARHGEF4,PPP6R2,MAML1,CTIF,EDN1,EDNRA,EN2,DLC1,ZNF589,FGF13,C1orf61,GART,RUNDC3A,GRIA1,BTN2A1,KCNK2,MAOB,MID1,MYCN,NTRK2,NUMA1,PALM,PHKG1,CAMKV,PRKCB,PTCH1,SH3GL3,KIF13A,RBM34,ATP10B,AJAP1,JMJD6,ZEB1,PSD3,HEY1,R3HDM1,FLRT2,VSNL1,ZNF142,MVB12B,JPH3" Drug 4214_DN Propantheline bromide [50-34-0]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.21E-06 1.08E-01 4.88E-05 5.55E-04 57 198 "PLA2G6,APP,PDE8B,MARCH3,ALDH4A1,SYNJ2,KRIT1,CBFA2T2,LY86,CSF1R,CTNND2,MFAP3L,EXOG,DTNA,DUSP9,CNNM1,EFNA3,EGFR,ZNF391,ETV1,FOXG1,SORBS1,DENND2A,MSL3,KCNMB4,GUCY1A2,SCIN,JAK2,PACRG,MATN3,TM6SF1,MGAT3,MN1,GIT1,PAK3,PBX1,RETREG1,ST8SIA5,GRAMD1C,PROX1,CNTLN,TMEM231,FAM184A,BEND5,IL17RB,SUPT20H,FBXO11,PEX26,TMCC1,SPTAN1,ELOVL4,SYT1,TRIM2,RIMBP2,SSBP2,ZKSCAN5,KCNAB1" Drug CID003645780 RS)-2-chloro-5-hydroxyphenylglycine Stitch 2.24E-06 1.10E-01 4.94E-05 5.61E-04 14 24 "ADORA1,ADORA2A,CNR1,FOXM1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,LIMS1,RELN" Drug CID006437837 CGP 39653 Stitch 2.24E-06 1.10E-01 4.94E-05 5.61E-04 14 24 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug CID000065749 13-methoxyibogamine Stitch 2.26E-06 1.11E-01 4.99E-05 5.67E-04 23 54 "CACNA1E,CALB1,FOXM1,GFAP,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,HTR2A,OPRL1,PDYN,RET,SOX10" Drug CID000001123 taurine Stitch 2.31E-06 1.13E-01 5.09E-05 5.79E-04 64 231 "ABAT,ADORA2A,ADRA1B,DGKZ,ATP1A2,ATP1A3,BID,CBS,KRIT1,CDO1,CHN1,CLCN3,CLCN4,CLTA,HAPLN1,SLC32A1,PPP1R16B,CTH,EDN1,RASGRP1,FGFR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,GGT7,GGT5,GLRB,GLUL,PCSK1N,GRIN2C,GRIN2D,CIT,KCNJ16,MAPT,FXYD1,PPP2R2B,PPP2R5E,MAPK3,MAPK4,MAPK7,KLK6,GSTCD,SCG5,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,ABCC8,TACR1,XRCC4,STMN4,SLC17A7,SLC17A6,NETO1,ST8SIA2" Drug CID000001738 homovanillic acid Stitch 2.32E-06 1.14E-01 5.10E-05 5.81E-04 34 97 "ABAT,ACHE,AMT,ATP1A3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CCK,CCKBR,QKI,DRD1,ENO2,GAD2,LOXL3,GRM2,KCNA1,KCNA2,MAOB,MYCN,NDP,PAH,QDPR,CASC3,SLC1A3,SST,VPS13A,MLST8,MGRN1,HHIP,TRH,NELFE" Drug DB01174 Phenobarbital Drug Bank 2.36E-06 1.16E-01 5.19E-05 5.91E-04 9 11 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA1,GRIA2,GRIK2" Drug CID000444055 AC1L9FMM Stitch 2.36E-06 1.16E-01 5.19E-05 5.91E-04 28 73 "ABCD2,HAP1,DMTN,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IGF1,IGFBP1,LRRC25,NUCB1,GPSM2,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A9" Drug 6340_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.37E-06 1.16E-01 5.20E-05 5.92E-04 53 180 "ADRB2,MTUS1,ARNTL,MARCH3,MARK4,BRINP2,ST3GAL5,WASF1,HIP1R,USP2,ABCG1,PDE4DIP,CTH,KIAA0513,JAKMIP2,C2CD2L,PLPPR4,ANKRD46,EFNA3,RGS17,ENO2,TAOK3,BAIAP2,NBEA,SORBS1,PNMA2,FYN,GLS,GUCY1B1,DIPK1A,INPP5B,KIF5C,MEF2C,MMP16,NUMA1,PCDH9,SERPINI1,PIK3CD,RETREG1,PLCD1,RGS4,STUM,SH3GL2,SH3GL3,KIF16B,WDR47,ZCCHC24,THSD1,RGL1,SYT1,KAZN,SSBP2,DNAJC12" Drug 2977_UP (-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.39E-06 1.17E-01 5.26E-05 5.98E-04 47 153 "TKTL1,MTUS1,BIN1,GAS7,DNAH17,NCOA1,CFLAR,SLC16A4,CD86,CD38,CHN2,CLOCK,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,GPRASP1,FAM13A,ING4,PRKAG2,TRAF3IP2,GALC,MEF2C,OLR1,PDE4B,PDE4D,SERPINI1,SMOX,PRKCZ,QDPR,TMEM255A,SEC14L1,SGK1,FAM214B,ARHGEF40,SPTAN1,EPB41L3,PLCB1,PDLIM2,TCF4,SLC44A1,TLR4,FLRT2,CLDND1,ZBTB38,NLRP3" Drug CID000005673 AC1Q646P Stitch 2.44E-06 1.19E-01 5.35E-05 6.09E-04 21 47 "PDE8B,ALDH7A1,CALM1,KRIT1,KCNA1,KCNA2,KCNA6,KCNB1,KCNH2,KCNQ2,KCNQ3,PDCD2,PDE1A,PDE1C,PDE2A,PDE4B,PDE4D,PDE1B,ENPP2,POU3F2,KCNAB1" Drug 6160_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ADORA3,AMT,PPP4R4,ADAM23,CAPN3,CHM,RAB33A,CLCN4,AKAP7,CRMP1,NCOR1,MICAL2,DAPK1,TSPAN5,TRMO,GABRA4,INPP5K,ZNF276,GLS,MAN1B1,ITIH2,VWA5A,OMG,CCSER2,NLE1,PLCB2,PMP22,PTPA,MAPK3,MAPK8,RAB3A,RAD52,ZCWPW1,RGS10,TMEM206,TCP11L1,FOXRED2,SBF1,FAM102A,SLC2A5,FAM214B,SLC20A2,THSD1,SYN2,KAZN,PSD3,TNS2,TEX15,AP4E1,SLC44A1,PARD3,RBFOX2,CADM1,VIPR2,TRIM9,KCNAB1" Drug 608_UP NU1025; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "GRAMD1B,LTBP4,BIN1,PDXK,ARRB2,CADM3,HIP1R,CCNT1,TAOK2,ARHGEF6,CTH,ECE2,CTIF,DBT,KLHL3,DMPK,ING4,EFEMP1,GAB1,GABRA5,SEPT9,NEU3,TXNL4A,LILRA2,GRIK5,GRM1,ADAMTS6,RASSF8,PADI2,IRF8,C2orf72,KCNJ5,KCNMA1,LAMA2,MBP,NAP1L1,NOS1,NOVA2,NPR2,NRGN,SMIM7,CCDC40,PLEKHB2,FOXRED2,KDM4B,WDTC1,DOK5,SP4,UHRF1BP1L,AJAP1,TNS1,SEZ6L,TRIO,TMPRSS5,MAP3K12,GDPD5" Drug 4682_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "NME5,TRMT9B,APBB2,ATP1A3,ADAM23,FUBP1,MTMR3,RAB28,NRXN3,ZFYVE9,CLCN4,ABCG2,RAB26,ARHGEF10,MFAP3L,SMG7,RABGAP1L,CHRDL1,EDNRA,SGK2,COQ7,FOXG1,CGREF1,PNMA2,C1QL1,GNG3,LPAR4,GPER1,RASSF8,LIG4,MAPT,NDP,NEUROD1,NOS1,SLC11A2,PIK3R1,RETREG1,STRN3,MAPK8,RGS10,GSTCD,CSRNP3,SOX2,SOX15,IZUMO4,COLGALT2,INKA2,ASTN2,GPR161,TIAM1,TK2,ZKSCAN5,WIPF1,LAT2,SCG2,FAM13C" Drug 4281_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ADD1,AK2,CDK13,ASPH,ATM,CFLAR,CA12,FOXN3,TCEAL2,VCAN,PDE4DIP,SMG7,PLPPR4,DNM2,DTNA,FEM1B,FCF1,MBNL2,ERCC2,SCARA3,HPCAL4,PDLIM5,TRAF3IP2,MSL3,POLL,RASSF8,AGFG1,IL6ST,INPP5B,NFIX,NLE1,STRN3,PPP5C,SNRK,SLC25A36,SCG5,ZFP30,PPP4R3A,CCDC88A,ZNF667,SP4,PSD3,SLC44A1,THRA,TK2,TMPO,R3HDM1,RPRM,VIPR2,XRCC4,SF1,ZNF74,WNK1,EVI5,KCNAB1,KAT6A" Drug 4248_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ACTN1,ADRB2,CDK10,ADGRB2,BCL7A,LHX2,RAB28,RAB26,NRG2,VCAN,HDAC9,AK5,ATN1,SGK2,CNNM1,OPTN,SUGP2,SORBS3,EPB41L1,DMTN,MTSS1L,STX2,EZH1,ST3GAL6,SEMA4D,PRELID3A,INPP5K,GBX2,RUNDC3A,GLYR1,GRM1,HMGCL,MID1,PBX1,NLE1,MAPK7,ZCWPW1,RGS7,KCTD17,FRMPD1,PPP4R3A,KANSL3,WDTC1,IQSEC2,CEP68,ASTN2,SMG6,SLC44A1,THRA,TNS1,RUNDC3B,AMACR,OSBP2,LMF1,WIPF1,NAV3" Drug 4441_UP chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "MRTFA,OGT,CDC14B,ATM,N4BP2L1,MYRF,CACNA2D1,CAMK2B,RUNX1T1,NRXN3,ZFYVE9,RCHY1,CTNND2,RIMS3,SMG7,SPOCK3,SRGAP3,HS3ST2,ATN1,EDNRA,ETV1,CEND1,F5,FAM198B,ATP8A1,FGF1,OLFM1,CAMSAP1,FOXG1,PDLIM5,GAP43,ALDH1L1,GLI2,GUCY1A2,HRH3,HTR2A,KCNB1,KHK,KIF5C,NCAM2,PTPRN2,KLHDC8A,FOXRED2,NTNG1,LIMS2,RIMS1,SOX10,ZNF423,MCF2L2,JMJD6,TEX15,BHLHB9,TMPRSS5,HIRA,PDIA2,MVB12B" Drug 7352_UP Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "LTBP4,ALK,DNAH17,KIF1A,BTRC,CDC42,SIPA1L1,PDE4DIP,DCAF8,GIT2,DNAJC6,DMPK,DSCAM,STX2,ATP8A1,FER,CAMSAP1,FHL1,DPYSL4,PDLIM5,HBS1L,GALC,SRCAP,RAB30,GLS,POLL,GNAO1,GNG3,GNG4,STON1,SPACA9,RASSF8,ATXN2L,IL6ST,MEIS2,LYRM9,NF1,PDE3B,PIK3CD,LRP12,APTX,RIPOR1,RAB3IL1,SBF1,ABLIM3,SLC22A4,RBM34,WDTC1,TROVE2,KIAA0930,PSD3,THRA,TMOD1,CABIN1,RUNDC3B,VAV2" Drug 3370_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ADD2,ADORA2A,KIDINS220,BIN1,OGT,N4BP2L1,CAMK2B,TAOK2,RAB33A,SEC14L5,SPOCK2,RABGAP1L,HS3ST2,DPP6,MBNL2,ING4,EN2,RASGRP2,PIPOX,CEND1,TUBB4A,FOXG1,FLNC,GCNT2,GPER1,GRM1,RASSF8,IGF1,ITIH2,KCND3,LMO2,MMP17,MSR1,NTRK2,NUMA1,EPN1,CEP41,PRKCB,PTAFR,RAD52,RIT2,STUM,ZC3H13,SPTB,NFASC,ZC4H2,ABCC8,VAMP1,ARC,WSCD1,PCDHGA10,HEY1,FLRT2,SLC17A7,KCNAB1,NUP214" Drug 6883_DN carmustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "C1QTNF1,AMT,SEMA7A,APBA2,APP,SEMA4G,ST3GAL5,HOMER3,CSF1R,VCAN,DZIP3,PHF14,CTNND2,FAM131B,ZFYVE16,KBTBD11,SGK2,SIDT2,ING4,LRRC23,ETV1,ATP8A1,TESK2,FGF1,FYN,TMEM8B,PSRC1,BACH2,SHISAL1,MEF2C,MIA2,MPP2,ZNF862,PDGFRA,C19orf57,SH3TC2,TTLL7,FUZ,FBXO11,ST6GAL1,KDM4D,ZKSCAN3,TNIK,SPATA7,ST5,SYT1,WSCD1,TCF4,TNS1,VGF,LAT2,TRIM9,REEP1,SLC30A4,GDPD5,MVB12B" Drug 4219_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "BAG4,VCAN,FAM169A,SLITRK5,TBC1D5,DBT,CNIH3,MFAP3L,KIAA0753,PLPPR4,CHRDL1,EXOG,COQ7,EPHA5,SPEG,ETV1,RRAGB,POLR1B,FGF13,ERAP1,GCNT2,GPD2,TDRKH,NR3C1,KLF12,AGFG1,SHISAL1,DIPK1A,MTR,NDP,CLDN11,PAK3,RETREG1,PTPRN2,RAD51D,RAD52,BEND5,SBF1,SCG5,FBXO11,FNDC3A,LIMCH1,BEX1,MAPK8IP3,VAMP1,ARHGEF9,IQCE,TRIM2,ARHGEF12,DNAH7,TK2,RUNDC3B,SSBP2,XRCC4,NDRG4,PLSCR4" Drug 4319_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "APBB1,APBB2,SEMA4G,ASPH,CFLAR,CAMK2B,SCARB1,CACNA2D2,SRSF11,FOXN3,ENTPD4,CRMP1,MICAL2,SPOCK2,SMG7,SRGAP3,ATN1,SEMA4D,CRCP,POLL,FERMT2,GPM6B,GSTM5,RASSF8,KLF12,IL6ST,KIF5C,VWA5A,MAP4,NFIX,CNOT4,NTRK2,NUMA1,STRN3,PTN,FAM120C,SLC25A36,KIRREL1,SEC14L1,CCDC88A,ZBTB43,TBCEL,TBL1X,SMG6,TCF4,PSD3,DICER1,THRA,TMPO,VIPR2,SF1,TFIP11,WNK1,EVI5,KCNAB1,KAT6A" Drug 582_DN butein; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ABR,APBB2,ADGRB2,CDC27,CHRNB2,CNTN1,IFFO1,PREPL,HAPLN1,AATK,HP1BP3,MAMLD1,EFNB3,EGFR,ELAVL2,RGS17,EN2,ERCC2,TAOK3,SEC23B,C1orf61,FYN,GAB1,GALC,GAP43,NEU3,GBX2,GLS,PRRC2B,GPR37,KCNJ5,MBP,MMP16,NAP1L2,NNAT,CCSER2,TRHDE,PACSIN1,C19orf57,PTX3,CLIP1,KLHL7,PLCB1,PSD3,PCDHA5,GPR161,TMPO,TUB,RPRM,CLDND1,ZNF23,EVI5,SLC17A7,KCNAB1,MPPE1,CAMK1G" Drug 5699_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ASTN1,ADAM23,CACNG1,CDH8,DNAJB5,MICAL2,RIMS2,PHYHIP,C2CD2L,DRP2,DSCAM,ECM2,EFNB3,EGFR,NRN1,FHL1,FOXF2,AFF2,RND1,LPAR4,GPR37,RAPGEF1,GRIA1,GRM8,TJAP1,INPP5B,KCNH1,KCNH2,MATN3,MMP16,NDP,NEUROD1,NF1,OMG,PDE4D,NLE1,PLP1,PPP1R1A,PPP2R2B,PRKCB,PTH1R,ACSM5,BAALC,RYR1,RASA3,SLC2A5,FAM214B,SORCS3,RBM34,VAMP1,SYN2,SPX,CHST5,FLRT1,SEMA3B,SLC17A7" Drug 5235_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "AGT,NME5,BIN1,APBB2,APC,APOC1,BCAS1,ASPH,CLGN,ADGRG1,SOCS6,B4GALT6,NECTIN3,CRMP1,CTH,KIAA0513,RASSF2,CTIF,RUSC2,SMG7,MBNL2,EPB41L2,PTK2B,FGFR1,ATP8A2,GLYR1,STON1,GPER1,GPR37,PTGDR2,KCNJ3,KCNN2,MEF2C,MYO7A,NTRK2,PCDH9,SERPINE2,LRP12,MAPK8,RGS10,CLIP1,SH3GL3,DOCK10,ST6GAL1,LIMCH1,TSNAXIP1,ATP10B,STX1A,EXOC7,PCDHGA10,BEX4,RUNDC3B,HIRA,PLPPR2,SCG2,EPM2A" Drug 2753_DN Syrosingopine [84-36-6]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "MTUS1,AK2,MRTFA,APBB2,APC,EPB41L5,BCAS1,ARHGDIG,ASPH,ATM,RIPK1,CFLAR,B4GALT6,SLIT2,PLAA,FAM189A2,ARMC8,SOCS5,GREB1,HDAC4,G3BP2,DNAJB6,HIPK3,RBM12,IQCG,TXNL4A,GLYR1,KCNJ3,KITLG,MMP16,NPR2,PC,PCDH9,PIK3R1,NLE1,LRP12,PRKAR1B,SIDT1,ELOVL2,RET,RIC8B,SAFB,IL17RB,SFPQ,SGK1,COA1,NXT2,NCDN,TMOD1,HIRA,UBTF,VGF,ZBTB38,WNK1,ST7,PHTF2" Drug 4105_DN Fusaric acid [536-69-6]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "LTBP4,MRTFA,BIN1,ANK3,PDE8B,BRINP2,MTMR2,CAMK2G,CCNT1,SCARB1,B4GALT6,QKI,HOMER3,ABI3BP,CREM,SIPA1L1,DSCAM,ING4,ANKMY1,ACSL4,ZNF589,FHL1,OGA,HBS1L,HTATSF1,FERMT2,STON1,IPO5,MAPT,MDM4,THYN1,CNOT4,SETD4,PDPK1,PTPA,PLPPR1,RIPOR1,RGS3,ROM1,RPS6KA2,CLIP1,FNDC3A,PPP4R3A,EPN2,WDTC1,SS18,PLCB1,POPDC3,TMPO,KAT6B,CABIN1,CLDND1,TFIP11,WNK1,UBE3B,IFT88" Drug 6510_UP Scopoletin [92-61-5]; Up 200; 20.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "RALGAPA1,NDRG2,PLA2G6,APBA2,SLC2A11,LDLRAD4,CACNA2D1,TAOK2,LHX2,HOMER3,WHRN,HP1BP3,DPP6,DTNA,EFNA3,EGR3,FGFR1,FOXF2,SEMA6C,PDLIM5,OGA,GAP43,SRCAP,GNAO1,GNAS,HSF2,ICA1,LIG4,MBD1,BCO1,OMG,LRP12,LRRN3,SAMD9,PTHLH,KCTD17,MRAS,SYBU,SLC11A1,SLC14A1,HECW1,UNC5B,ARHGAP26,PHLDB1,STX1A,IQCE,TRIM2,DOCK9,PSD3,ARHGEF12,SLC44A1,NSD2,WNK1,STMN4,SEMA3B,SSPN" Drug 6727_UP Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ACTN2,AGT,NR0B1,ANK1,SLC4A4,ATP2B3,N4BP2L1,AZGP1,ADGRB2,PROM1,CAMK2A,CAPN3,RUNX1T1,SYNGR3,ARHGAP22,NRXN1,CREM,DBT,MFAP3L,DTNA,DYRK1A,ABCC9,HIPK3,ING4,ELN,FABP7,SRCAP,GFER,RUNDC3A,GNAL,GNAO1,AP4S1,PADI2,MT1M,MX1,NELL2,PDE4D,GPR85,PPARA,SAMD9,PTPRB,RGS4,TMEM206,IL17RB,PKNOX2,ZSWIM8,LMO3,ATP10B,ARC,SYN2,SYT5,THRA,TLR4,WNK1,DNALI1,STMN4" Drug 3274_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "MTUS1,ALAD,ATM,RIPK1,BCL2L2,CFLAR,ST3GAL5,SYNJ2,SCAPER,ZFYVE9,NMT2,QKI,NIPBL,SLC4A7,NCOR1,GREB1,GPRASP1,NR1D2,FEM1B,FCF1,SORBS3,IRAK4,EXTL2,EZH1,FECH,BAIAP2,CINP,SEPT9,ARFIP1,GPR37,GSN,MPP2,NFYA,NUCB1,PDE3B,SLC25A23,PMS2,PRKACB,SLC25A36,SAFB,ZNF821,SGK1,SH3BGR,RCOR3,MAPKBP1,SS18,TBL1X,EHBP1,TPD52,TPM1,HIRA,XRCC4,NAV2,MPPE1,EPM2A,RNF170" Drug 3846_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.47E-06 1.21E-01 5.37E-05 6.11E-04 56 194 "ADCY2,ADD2,APOC1,PPP4R4,PLA2G4C,STX16,MTMR3,CACNB2,RUNX1T1,NEURL1,CLGN,ADGRG1,LHX2,FADS2,NCOR2,GREB1,DAPK3,DMD,HS3ST2,ATN1,TSPAN5,ERBB2,SPEG,CORO2B,CAMSAP1,PDLIM5,CAMKK2,SRCAP,C1QL1,GLYR1,GSN,KLF12,IL6ST,LSS,KITLG,MMP16,GIT1,MX1,TMOD2,PIK3CD,TNPO2,PRKAR1B,MAPK10,FAM120C,RAD51D,RGS12,SCN8A,ST6GAL1,PPP4R3A,ZBTB43,ATP11A,CHST5,UBE3A,ETNPPL,NT5M,PHTF2" Drug CID000000224 AMP group Stitch 2.47E-06 1.21E-01 5.38E-05 6.12E-04 133 579 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,BRAP,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,LRFN2,ADRB2,AK2,SEMA6A,AMPD2,AMPD3,LRFN1,APC,DGKZ,GPAM,DGKD,NT5C3B,APOC2,LGR5,ALDH7A1,DST,GYG2,CALM1,CARS,P2RX6,CD38,ENTPD2,DGKI,LRBA,UBE2L6,FADS2,FHL5,AKAP6,CREM,CS,CTNND1,EARS2,DGKB,DGKG,DCTN1,AK5,DYNC1I1,FARSB,EDN1,ENO2,GPHN,ZNF461,ACSL4,STRADA,PRKAG2,UBE2E3,AK8,TPK1,CAMKK2,CAB39,RAPGEF6,ATP8A2,ACSS1,GCK,PPARGC1A,CRCP,GNAL,GNAS,CNDP1,GPR12,LPAR4,RAPGEF4,GYG1,CPT1C,IDH3A,KCNMA1,LIG4,P2RY13,NCAM1,NPPA,OGDH,P2RX7,P2RY1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PKM,EXOSC10,PRKAB2,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,PRPSAP2,MASP1,PTHLH,PTH1R,PYGM,ACSS3,RET,RNASE1,RPL38,SARS,FNIP1,FNDC3A,SEPHS1,SLCO1A2,NMNAT2,SST,ADHFE1,ACSBG1,ACSL6,SLC19A3,AHCYL2,TLR4,TRPM2,HSPBP1,UBE2H,VIPR2,P2RY12,ZNF195" Drug CID000002712 chlordiazepoxide Stitch 2.49E-06 1.22E-01 5.41E-05 6.15E-04 38 114 "ABAT,KCNH8,ARSE,CACNA1I,CACNA1G,WASF1,CCK,CCKBR,USP6NL,KIAA0319,SV2B,ABI1,ABI2,STX2,EPS8,ZMYND10,BAIAP2,CELF1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,AHCYL1,NCKAP1,GRM5,NCF2,OCRL,EFHD1,TACR1,ZEB1,ZNF384,TRH" Drug ctd:C070417 Win 55212-2 CTD 2.55E-06 1.25E-01 5.55E-05 6.32E-04 24 58 "ADORA2A,APP,ARHGDIA,CNR1,EGFR,EFS,VPS26C,RTN3,GCK,MAP2,MAPT,MAT2A,TAGLN3,CDK14,SERPINE2,PACSIN1,PPARA,MAPK3,MAPK8,MAPK9,PTPRN,SLC1A2,WDR47,NDRG4" Drug 4755_DN 0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.56E-06 1.25E-01 5.55E-05 6.32E-04 54 185 "MARCH3,ATM,MPDZ,BLM,BMP7,SYNJ2,KRIT1,CBFA2T2,FOXN3,STOML1,SMARCAL1,C2CD2,CREM,ABCG1,MICAL2,KIAA0513,GIT2,ARNT2,DPH1,MAMLD1,KMT5B,EGR3,TUBD1,VPS13B,CHST15,NBEA,TACC2,GPR19,JAK2,KLC1,MBP,SSH1,RBBP6,RET,KIF16B,SHANK2,SLC15A2,KDM4B,ERC1,CLASP2,CEP68,ZC3H4,ARHGEF9,TACC1,KAZN,MTCL1,FAM208A,EHBP1,TRIM2,SMUG1,LMF1,ZIC1,ZNF189,FZD3" Drug 7047_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.62E-06 1.29E-01 5.57E-05 6.34E-04 52 176 "DPF1,ABAT,ADRB2,ARNTL,MARK4,ST3GAL5,CDK5R2,ABCG1,PDE4DIP,CTH,DNAJC6,PLPPR4,SIDT2,EFNA3,FAM13A,EPB41L2,TBC1D16,TAOK3,TESK2,BAIAP2,DPYSL4,SORBS1,PDLIM5,PCDH17,GLS,STON1,GUCY1B1,ITGA7,KIF5C,MAP2,MMP16,PCDH9,SERPINI1,PIK3CD,RETREG1,PRPH,ENOX1,RBBP6,RGS4,RPS6KA2,SH3GL2,SH3GL3,ASAP3,ARHGAP26,THSD1,RGL1,SYT11,SYT1,TGFBR3,DNAJC12,PLPPR2,TRIM9" Drug 6546_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.62E-06 1.29E-01 5.57E-05 6.34E-04 52 176 "ADRB2,ARNTL,ATM,ADGRB2,ST3GAL5,HIP1R,USP2,NRXN3,ABCG1,PDE4DIP,CNTNAP2,CTH,DNAJC6,C2CD2L,PLPPR4,RGS17,EPB41L2,F3,TBC1D16,PTK2B,TUBB4A,TAOK3,BAIAP2,HPCAL4,SORBS1,FYN,RUNDC3A,GLS,STON1,GUCY1B1,KIF5C,MMP16,ODF2,PCDH9,SERPINI1,CCSER2,PRPH,RGS4,RPS6KA2,SH3GL3,TNIK,SAMSN1,THSD1,ELOVL4,RGL1,SYT11,SYT1,SSBP2,HIRA,DNAJC12,TRIM9,SLC30A3" Drug 5428_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ACTN2,ADD2,FZD9,ADRA1D,CNTNAP1,PLA2G4C,MARK4,SLC4A4,ST3GAL5,BAIAP3,CAMK2B,CAST,ADGRG1,TMEM59L,VAX2,NRG2,NCOR2,VCAN,DRD1,HIPK3,EN2,EFCAB2,GAD1,NR3C1,GSN,GSTM5,ATXN2L,KCND3,KCNQ3,MOBP,MSR1,SLCO1C1,OMG,PGAM2,PURG,PPP2R2B,PTPRH,PTPRO,ZFHX4,SATB1,ZNF821,SLC1A7,SHANK2,ZCCHC24,SOX10,ZHX3,IZUMO4,HECW1,ZNF423,SPTAN1,RBM26,COLGALT2,ARC,DOCK9,SCG2,NAV2,ITM2C" Drug 5079_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASIC1,ACTN2,ADORA2A,PLA2G6,BBOX1,ANK1,APAF1,SCAPER,BAIAP3,USP2,MAGI1,CNTFR,IQCK,CREM,CREB5,CRMP1,VCAN,MFAP3L,DSCAM,EFNB3,TNK2,CALCRL,SCML2,CORO2B,OLFM1,FGFR1,FAM49B,TBR1,ATP8A2,RAB30,PRUNE2,LILRA2,GPR22,GRM7,LIFR,LSS,MATN3,MDM4,KITLG,NEUROD1,NOVA2,PPARA,PROX1,PID1,CCDC40,RGS10,TCP11L1,ST6GAL1,PREX2,SLC8A1,SLN,KIF21B,PHLDB1,ADGRL3,TBCEL,SEZ6L,LILRA4" Drug 4775_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "BEGAIN,CDC42BPA,FAM131A,APOC1,ASPH,ALDH4A1,LDLRAD4,CD86,RCBTB2,FOXN3,TPP1,ARHGEF6,CREB5,ARHGEF10,OSBPL3,HEPH,MAGI2,SLC12A6,SIDT2,EFNA3,ELAVL3,DMTN,GPR153,FYB1,SIGLEC8,DISC1,KLF12,SYNPO,IRF8,KCND3,KCNMA1,KHK,TAGLN3,NCAM1,NF1,NOVA2,OPRL1,PDE4B,EPN1,PTPRD,FAT4,TRIM68,NUDT11,PPP1R9A,ZNF365,SLC1A7,SLC14A1,PLCB1,EXOC7,ZEB1,PCDHA5,TEX15,CLDND1,SLC30A3,WNK1,ADAMTS9,ST7" Drug 4210_UP Diflunisal [22494-42-4]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "APC,CDC14B,ZSCAN18,ATP2B3,RGS11,CACNA2D1,CACNG1,CBLN1,USP2,MAGI1,DLGAP1,NRXN3,ABCG2,CNTN1,AKAP5,SPOCK2,DBT,ST8SIA3,OLFM1,EFCAB2,PDLIM5,GAB1,GAD2,LYVE1,GNAL,GPR17,IL1RAPL1,KLF12,IL6ST,KCNB1,KCNJ5,KIF5A,MYH3,NF1,OLR1,CAMKV,PPP2R2B,LRRN3,PRKAR1B,PRKCB,PTCH1,ACSS3,C1orf54,GAL3ST4,KCTD17,SEMA6D,SCN3A,PKNOX2,SLCO1A2,MAPK8IP3,PLCB1,PHF24,CRTC1,CHST5,PARP6,SEMA3B,MVB12B" Drug 3774_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "TRMT9B,SEMA7A,APAF1,RASL11B,ATP2B2,KIF1A,CACNA1G,CFAP410,SRGAP3,ATN1,DYRK1A,EFNB3,MTSS1L,NCALD,CEND1,AGAP2,SIGLEC8,GNAL,GNAO1,MCHR1,IL1RAPL1,KLF12,IRF8,IGFBP1,MMP16,MMP17,MOBP,CD200,MX1,NUMA1,OPCML,PC,GPR85,PFKFB4,MTRF1L,PLXNB1,PPP2R2B,PROX1,PTH1R,PTPRH,RASGRF1,PAQR6,SH3BP2,PKNOX2,SLC8A2,SLC11A1,RIMS1,SNCA,LMO3,THSD1,SYT11,PLCB1,SYP,MCF2L,TCF7,VAV2,MKRN3" Drug 2487_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ABAT,AP2A2,MRTFA,APOC1,CDK10,SLC4A4,SYNJ2,SGCE,C5,ARHGAP33,CHM,EPS15L1,STOML1,CNTN1,CRY2,EDRF1,RABGAP1L,EFNA3,LRRC23,PIPOX,DLC1,KAT8,FGFR1,IQCG,GAB1,GABRA2,ALDH1L1,HTATSF1,GRM1,ATXN2L,MAP4,MDM4,ZNF862,NCAM1,NUMA1,OXTR,PIK3CD,PLCD1,PTPA,PTCH1,PTN,PTPRN2,RAB3A,ZCWPW1,ARHGEF10L,GALNT10,MRAS,PREX2,PEX26,JMJD6,CAMSAP2,PDLIM2,THRA,TRPS1,SYNC,MAP3K12,SENP7" Drug 5813_DN Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "BIN1,APP,MTMR9,SPAG9,CDH2,CNOT8,EPS15L1,RAB28,WHRN,NCOR1,ARHGAP32,RUSC2,SGSM2,TMCC2,TRAPPC9,DYNC1I1,LPAR6,EN2,FECH,FHL1,PDLIM5,OGA,DISC1,COPS8,RNFT2,DHX35,DIPK1A,ITPKB,KIF5C,MIA2,MITF,NOVA1,OCRL,PBX1,PDGFRA,SSH1,FSD1,PTHLH,RFX5,MAP6D1,SUPT20H,WDR37,ELMO2,LIMCH1,TNIK,MAPK8IP3,COBL,PDLIM2,SLC35G2,AHCYL2,ZNF34,CBX5,NR2C2,UBTF,PLPPR2,LMF1,XRCC4" Drug 370_DN troglitazone; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "CDC42BPA,APBB2,ATP1A2,BCL7A,GYG2,NEURL1,KIAA1549L,TJP2,PICK1,TCEAL2,SEC14L5,ECE2,KIAA0586,GIT2,PARD6A,DTNA,SORBS3,KCNMB4,RNFT2,KCNA1,IPO5,NF1,NNAT,NPR2,PALM,PDE1C,ABCB1,PHKG1,POLG,PRKAR1B,MAPK10,PRPH,MASP1,PLPPR1,SPDL1,RALGDS,RGS3,TMEM206,KCNIP1,DGLUCY,STUM,SH3GL3,SHANK2,KBTBD4,HECW1,UHRF1BP1L,CAMTA2,NXT2,ANKRD12,KAZN,TCF7L2,OBSL1,BHLHB9,RBFOX2,HSPBP1,VSNL1,XRCC4" Drug 7210_DN Milrinone [78415-72-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASPHD1,ABHD6,ADCY6,ANK3,DGKD,ARRB2,CFLAR,RAB29,CCNT1,SCARB1,LHX2,QKI,IQCK,SOCS5,PDE4DIP,DZIP3,TBC1D5,FBXL5,SMG7,RABGAP1L,DNM1,SEZ6L2,EDNRA,SUGP2,EGFR,COQ7,VPS26C,FGFR1,DPYSL4,ATP2C1,B4GALNT1,ERAP1,TXNL4A,MBD1,MPP2,NCAM2,PDE4A,SSH1,RETREG1,MBOAT7,TMEM104,SEC61A2,FBXW7,RXRA,SMTN,MAPKBP1,ITPRID2,ELOVL4,ARHGEF9,TACC1,TCF7L2,ARHGEF12,METTL3,UBE3A,LMF1,PRDM10,EPM2A" Drug 4201_UP Atovaquone [95233-18-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NDRG2,PKP4,CDK10,CADM3,N4BP2L1,SCAPER,BTRC,HAP1,SYNGR3,MAGI1,FOXN3,CHN2,CLCN4,PLCH2,DCT,AK5,ARNT2,DTNA,ECM2,EFNB3,SPEG,HPCAL4,ERGIC3,ERAP1,DISC1,PCDH17,RAB30,GNAO1,CACFD1,PTGDR2,HNMT,VWA5A,LSS,NF1,NPTX1,OLR1,OMG,CAMKV,PNMA3,SPATA6,PTAFR,PLPPR1,ROM1,TMEM206,TRAPPC13,ZFP30,DZIP1,ZNF334,SNAP25,KIF13A,TBCEL,PCDHA5,TEX15,WIPF1,KCNK12,WNK1,SLC17A6" Drug 6321_DN 2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "AP2A2,AK2,AMT,APC,APOC1,SEMA4G,ATM,CACNB2,IQCK,NCOR2,GPRASP1,GIT2,DCTN1,MFAP3L,RUSC2,SPOCK3,SGSM2,FEM1B,OPTN,EGFR,SORBS3,NCALD,ZNF589,FGF1,FGFR1,TRMO,FAM49B,CGREF1,FYN,DISC1,SRCAP,GLYR1,GNG4,RASSF8,KLF12,BACH2,SHISAL1,TJAP1,LIFR,MN1,NDUFA5,NUCB1,CNNM2,RIPOR1,MAPK12,SBF1,ASAP3,NLGN1,SMARCA4,SMARCC2,SMARCD3,IFT122,WDTC1,THSD1,CEP68,SSBP2,XRCC4" Drug 4234_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "SLC12A5,MTUS1,NR0B1,SEMA6A,DDO,DNAH17,ATP2B3,B3GALT2,RGS11,SYNJ2,CFAP410,CACNG1,CRLF1,NRXN3,FAM149A,CSF1,MICAL2,PDE4DIP,CNTNAP2,RIMS3,CTIF,DCT,MFAP3L,ST8SIA3,FGFR3,SIGLEC8,SYT17,GLI2,GRIK3,GRIN2C,HTR2A,SHISAL1,KCND3,MMP16,MOBP,ADAM22,NCAM1,NNAT,CAMKV,EPN1,PURG,GAL3ST4,SEMA6D,SCN2B,SLC6A9,ZNF415,PDZRN3,SOX2,DDN,SPART,MCF2L,SZT2,TRO,VIPR2,KCNK12,STMN4,CAMK1G" Drug 6608_UP Nifurtimox [23256-30-6]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADD2,C1QTNF3,ATP1A3,SYNJ1,BAIAP3,KALRN,CSF1R,VCAN,CHRDL1,DRD1,ZNF391,F5,REEP2,KIAA1109,FGF1,FOXG1,PRELID3A,NEU3,SRCAP,LYVE1,GUCY1A2,ATXN2L,KLF12,HTR2A,IGFBP1,IL12A,ITGA7,ITIH2,MAG,MAP4,MOBP,NPY,PALM,PDGFRA,PPP2R2B,PRKAR1B,PRPH,PTN,PTPRB,CCDC40,C1orf54,TMEM206,PRR5L,IL17RB,ASAP3,CNKSR2,SNCA,CDK19,INKA2,OBSL1,PCDHA5,TMOD1,TRIO,TRPC3,VIPR2,KCNAB1,GAN" Drug 4206_UP Pepstatin A [26305-03-3]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "MRTFA,GAS7,SPTBN4,DDX3Y,NRP2,SYNJ1,SCARB1,CDC42,CNOT8,CLCN4,DNAJB5,CNTN1,CSF1,PDE4DIP,CNTNAP2,RIPOR2,RIMS3,DTNA,EDIL3,HIPK3,TNK2,ETV1,HPCAL4,PRELID3A,DENND2A,DISC1,GATM,GPR17,PTGDR2,IGFBP1,KCNJ5,LAMA2,SMAD1,KITLG,ADAM22,LYRM9,NF1,PDGFRA,PIK3CD,PPARA,PTN,GAL3ST4,RGS3,NEK11,FBXO11,PREX2,OGDHL,SNCA,SCN3B,ZC3H13,MCF2L,PCDHA6,TK2,R3HDM1,PRMT8,FLRT2,KCNAB1" Drug 6452_UP Tyloxapol [25301-02-4]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADGRF5,N4BP2L1,BCHE,SGCE,CACNA1I,CFAP410,CD86,ARHGEF2,WHRN,TENM4,PDE4DIP,CNTNAP2,SNPH,SPOCK2,CTIF,MYEF2,DMPK,TNK2,LRRC23,NRN1,ATP8A1,FGFR1,CAMSAP1,EFCAB2,GABRA5,GAD2,ERAP1,GCK,GFER,USP19,GLI2,IRAK3,HLF,ICA1,KCND3,KCNJ5,KCNMA1,KIFC3,MAPT,MMP16,ADAM22,NCAM1,NF1,OPCML,SLC25A23,MAPK7,TCP11L1,FNDC3A,SNCA,FAIM2,HECW1,ACSBG1,ZEB1,GPR161,TGFBR3,SEZ6L,NSD2" Drug 4687_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "RALGAPA1,TRMT9B,AMPD3,APBB2,CDC14B,ATP1A2,CFLAR,SYNJ2,SCAPER,CAMK2G,DLGAP1,CHRNB2,FAM149A,AKAP12,CTH,ATN1,DTNA,SGK2,EFNB3,EN2,DMTN,EFS,PIPOX,EZH1,DLC1,OLFM1,GAB1,GAD1,LYVE1,RUNDC3A,GPM6B,ADAMTS13,GRIK5,NR3C1,GUCY1A2,MAG,MAOB,MMP16,NOS1,PDE4B,PENK,PMP2,ZDHHC14,ZFHX4,RPS6KA2,ZNF821,FRMPD1,SMARCD3,LIMCH1,ZC3H13,ARHGAP26,SYN2,CABIN1,TRPC3,REEP1,SCG2,SEMA3B" Drug 2292_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ALCAM,CDC42BPA,GAS7,DNAH17,RASL11B,RGS9,GYG2,CACNA1I,AKAP7,SNCAIP,NCAN,SEC14L5,RIMS3,DAPK1,EN2,KCNMB2,ERCC2,SPEG,NRN1,FGFR1,TPK1,GAD2,SRCAP,LYVE1,LPAR4,BACH2,ITIH2,KCNH1,KPNA5,MDM4,ADAM22,MX1,NNAT,NPTX2,CLDN11,PFKFB2,MTRF1L,CDIP1,RELN,GDPD2,PTCH1,RAB3IL1,KCTD17,SH3BP2,SLC6A9,CXXC4,SORCS3,SNCA,CDK19,SPART,MAPK8IP3,PCDHA5,TMOD1,FAM155A,FLRT1,ADAMTS9,KCNAB1" Drug 6700_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "C1QTNF3,MRTFA,APAF1,APC,ASCL1,ATP6V0A1,SCAPER,CALB2,KALRN,CHRNB2,TAOK2,CLCN4,COL9A2,HAPLN1,VCAN,PHF14,RIPOR2,SPOCK2,MFAP3L,ATN1,DTNB,EDIL3,EDN1,EFNA3,EFNB3,MBNL2,TNK2,ETV1,CACNG3,ZNF589,FGFR1,FOXG1,CAMKK2,GPR22,CACFD1,GRM7,VWA5A,ADAM11,AFDN,P2RX7,MAPK8,ACSS3,RPS20,ANKRD6,SLC6A9,SLCO1A2,OGDHL,ZSWIM8,EMC1,HECW1,AP4E1,TIMP4,R3HDM1,TPM4,VLDLR,NSD2,EVI5" Drug 4119_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NME5,AK2,BIN1,AMT,APLP1,APOC1,ARRB2,ATM,GYG2,B4GALT6,QKI,CRMP1,SIPA1L1,SDC3,RIMS3,RUSC2,MAGI2,TOM1,SGK2,EGFR,ING4,EN2,EZH1,FGFR1,FAM49B,HBS1L,DISC1,SRCAP,PRRC2B,GRB10,GRM8,ITIH2,KCND3,KCNF1,ADAM22,NUMA1,SERPINI1,PIK3CD,LRP12,PPP2R2B,MAPK8,GON4L,TMEM104,RPS6KA2,SLC1A7,BTBD7,LIMCH1,SNCA,ZHX3,EMC1,ZBTB43,TROVE2,ATP11A,EXOC7,PARD3,CDK20,KCNAB1" Drug 7214_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "DPF1,ARID1A,APBA2,PDE8B,CFLAR,KSR1,CACNA1G,THSD7A,CAMK2B,CBFA2T2,CNTN1,CRY2,ARHGEF10,CNTNAP2,SDC3,SPOCK3,SORBS3,EML1,DMTN,RASGRP2,DLC1,FGFR1,GAD1,MYOZ2,ALDH1L1,GLS,ATF7,GRM8,TJAP1,IL6ST,INPP5B,JAK2,MSI1,NF1,NPR2,C19orf57,LRRN3,MAPK8,PEX5,RAD52,RALGDS,CNKSR2,FAM214B,KANSL3,SLN,CXXC4,SOX10,ATP10B,PHLDB1,TRIM2,DAAM2,RIMBP2,TRO,TRPC1,ITM2C,PHTF2,SSPN" Drug 591_DN "N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Down 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "BIN1,OGT,ARNTL,CDK13,RASL11B,CADM3,RUNX1T1,ARHGAP33,FOXN3,FAM189A2,CP,CDC42BPB,NCOR1,NR1D2,DSCAM,DNAJB6,EFNB3,SORBS3,MRNIP,ZMYND10,ZNF589,HPCAL4,NEU3,PTPRT,IGF1,TJAP1,MBD1,OXTR,PAK3,PFKFB2,SUSD4,RASGRF1,ARHGEF10L,RLBP1,RNASE1,ZFHX4,TMEM206,SEMA6D,SELL,SH3BP2,SH3GL3,FUZ,NTNG1,SLA,SLC11A1,SLC20A2,KDM4B,DOK5,SRPK2,PHLDB1,DNMBP,TNS2,TEX15,THBS4,TRIO,TMPRSS5,SLC17A7" Drug 3603_UP Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "SYN3,MRTFA,TRMT9B,ASCL1,MARK4,ATP2B2,CFLAR,CACNG1,CALB1,USP2,CHRNA4,CABP1,NCOR2,OSBPL3,ATRNL1,GSDME,RABGAP1L,DLG2,TRAPPC9,CDON,SGK2,MBNL2,OLFM1,FLNC,NEU3,GPR22,GRIK5,GRM7,HTR2A,KCNB1,KIF5A,KIFC3,LIFR,MID1,TAGLN3,NUMA1,OMG,PDGFRA,PACSIN1,TNPO2,PTAFR,ASAP3,PKNOX2,SNCA,FAIM2,TNIK,IZUMO4,ACSL6,HIF3A,TEX15,PRMT8,TRIO,TRPC3,XRCC4,NT5M,SCG2,NUP214" Drug 7230_UP Convolamine hydrochloride [500-56-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASIC2,FZD9,AK2,APBA2,APC,APLP1,ALDH4A1,CCDC181,CA12,NEURL1,CLGN,SOCS6,FAM189A2,AKAP6,BAG4,CSF1R,SDC3,GREB1,GIT2,DTNA,CNNM1,ERCC2,REEP2,DLC1,BAIAP2,AGAP2,GLYR1,TDRKH,GRK4,SPACA9,GRM8,GSN,ATXN2L,IL6ST,ITIH2,MAN2A2,MBD1,KITLG,MITF,MSI1,MYT1,LRP12,PRPH,GTDC1,FUZ,WDTC1,DOK5,TTBK2,SYT5,SEMA4A,WSCD1,PSD3,TMOD1,ZKSCAN5,SLC30A3,MAP3K12,HPS4" Drug 3353_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NME5,APC,SLC4A4,ATP2A2,BAIAP3,KALRN,RUNX1T1,CHRNB2,CLCN4,FAM189A2,NCOR2,RUSC2,ATN1,FRY,CELSR3,DMTN,LRRC17,ERCC2,DLC1,OLFM1,FHL1,FLNC,SORBS1,PDLIM5,GAB1,GAD1,INPP5K,RUNDC3A,GLYR1,GRM8,C2orf72,ITGAM,KCNQ3,LAMA2,NF1,OMG,PCDH9,PDE3B,PDE4B,TNPO2,MED1,CEP41,PTHLH,C1orf54,ZNF493,MYH14,SELL,DOCK10,SLC9A5,WDTC1,ZC3H13,MAPK8IP3,ABCC8,TBCEL,ZFPM2,VIPR2,EMSY" Drug 2354_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "PLA2G6,ALK,BIN1,AMT,AQP4,MARK4,CFLAR,BMP7,GYG2,LDLRAD4,CBFA2T2,B4GALT6,RAB33A,STOML1,SULT4A1,HOMER3,SIPA1L1,ZFYVE16,DCC,RABGAP1L,TRAPPC9,E2F5,SIDT2,TNK2,DMTN,NCALD,FGFR1,CAMSAP1,FOXG1,GABRA2,SIGLEC8,MSL3,LPAR4,GRIN1,KCNMA1,KCNQ3,MAPT,MMP16,MPP2,GIT1,MYCN,OLR1,P2RX7,PENK,PLTP,TCP11L1,SEC14L1,SH3BP2,SNCA,KDM4B,WDTC1,NCDN,SYT11,THBS4,TK2,SLC17A7,KCNAB1" Drug 3445_DN Vidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "EPB41L5,NCOA1,BCL7A,ST3GAL5,TAOK2,CLCN3,QKI,BAG4,ARHGEF10,TBC1D5,DAPK3,SGSM2,DSCAM,TOM1,E2F5,FCF1,STX2,GALC,NCKAP1,GCNT2,GLYR1,GPD2,GPR37,CNTRL,ARHGAP19,HNMT,DHX35,IPO5,LSS,MBD1,MIA2,LYRM9,PC,NLE1,ZCWPW1,ARHGEF10L,MYH14,SAFB,AMBRA1,BTBD7,ZHX3,CDK19,TROVE2,PLCB1,TRIM2,TIAM1,PARD3,TRPC1,UBE3A,PLPPR2,KLC2,XRCC4,ZBTB14,GDPD5,HPS4,SMIM8,PHTF2" Drug 3265_UP "Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ABHD6,NDRG2,ADD2,GAS7,ASCL1,PDE8B,CADM3,GYG2,HAP1,CBFA2T2,KCNAB3,GPR37L1,TPP1,RIMS3,RUSC2,C2CD2L,MAGI2,TMCC2,SHANK1,SGK2,HIPK3,SIDT2,MBNL2,TMEM35A,ALDH1L1,RUNDC3A,GLS,MSL3,LPAR4,CACFD1,LAMA2,VWA5A,MEIS2,CD200,CNOT4,NPPA,SLC25A23,PACSIN1,ELOVL2,TRIM68,SLC11A1,DOP1A,KIF21B,ZC3H13,LMO3,TROVE2,CAMTA2,POPDC3,SYNE1,GPR161,ZNF34,TNS1,TPM2,EMSY,DNALI1,ITM2C,KAT6A" Drug 4984_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ABHD6,ARID1A,NDRG2,TRMT9B,APAF1,PPFIA3,MARK4,SLC4A4,ATP2A2,ADAM23,BAIAP3,CACNA2D2,HOMER3,CRMP1,SNCAIP,ARHGEF10,EXOG,SIDT2,ING4,SPEG,AGAP2,RUNDC3A,GPER1,GSN,IRF8,KCNH2,KCNJ5,KCNMA1,KCNN1,KCNQ3,KIT,VWA5A,NEUROD1,KCNK10,PPP5C,MAPK8,MAPK10,RAD52,ZNF493,KCNIP1,BCAN,RPH3A,SLC11A1,SNCA,TROVE2,PHLDB1,POPDC3,PSD3,PCDHA5,SPX,CABIN1,CDK20,LMF1,WIPF1,LAT2,KCNK12,SCG2" Drug 5415_UP Vigabatrin [60643-86-9]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "MRTFA,AMPD3,APBA2,APC,GAS7,APOC1,MPDZ,BAIAP3,CA4,CACNA1D,CAMK2G,CBFA2T2,CHN2,CLCN4,CNTN1,CNTNAP2,USP6NL,EDNRA,SGK2,EFNB3,DLC1,FGFR3,FHL1,TRAF3IP2,RAB30,PRRC2B,PCLO,NR3C1,GRM8,ITIH2,ITPKB,JAK2,KCNN1,NOS1,CNOT4,NUMA1,PDE3B,PIK3R1,LRP12,PPARA,GRAMD1C,PTN,ZFHX4,ZNF365,SNCA,RBM34,DOK5,ATP10B,TROVE2,FAM168A,VAMP1,TRIO,UBE3A,WIPF1,WNK1,SLC17A7,SLC17A6" Drug 2216_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASPHD1,NME5,CDC42BPA,APAF1,SLC2A11,ADGRB2,RAB29,CBFA2T2,CDH8,ADGRG1,STOML1,DOCK4,RASSF2,HEPH,RUSC2,DRD1,ATN1,EFNB3,MBNL2,VPS13B,NCALD,FGFR1,HPCAL4,EFCAB2,SORBS1,FYB1,GPR37,GRM3,SCRG1,ITGAM,KCNC1,TAGLN3,ZNF862,PCBP3,NTRK2,P2RY1,TREM2,CAMKV,LRP12,PKN2,MAPK7,RAD52,SEMA6D,SH3BP2,FAM214B,KIF13A,KIF21B,TROVE2,SAMSN1,HEY1,HEY2,TRPC1,UBE3A,PDIA2,XRCC4,SLC17A7,JPH3" Drug 4209_DN Zardaverine [101975-10-4]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASPHD1,PLA2G6,C1QTNF1,AMT,CDC42BPA,ANK3,SEMA7A,KYAT1,SH2B1,AATK,VCAN,RIMS2,DCAF4,C2CD2L,SLC12A6,DTNA,CNNM1,ZNF391,TUBB4A,FGF1,GBX2,GCNT2,GNG4,GPM6B,KLF12,INPP5B,KIFC3,PACRG,MGAT3,PAK3,ENPP2,PIK3R1,CNNM2,BCAS3,PTPRH,RAD51D,RALGDS,SH3TC2,FAM184A,RGS10,GSTCD,FBXW7,CSRNP3,ATXN7,IL17RB,DOCK10,NLGN1,ANKRD6,EXOC7,TMEM121,ZNF34,RUNDC3B,NDRG4,ZNF225,NAV3,KCNAB1,MPPE1" Drug 5543_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "RALGAPA1,ACTN2,TRMT9B,BIN1,CDC14B,ARRB2,DNAH17,MARK4,ASTN1,HAP1,KCNAB3,CLGN,CLCN4,COL9A3,RCHY1,CSF1R,CNTNAP2,RIMS2,EDRF1,DBT,SGSM2,DTNA,ST8SIA3,MBNL2,CDKL3,BAIAP2,FHL1,GAD2,GPR22,GRIN1,GSN,ICA1,IGF1,INPP5B,JAK2,KCNH2,KCNJ10,IPO5,LIG4,MID1,NFYA,PDE4B,SLC25A23,POLG,LRRTM4,ASIC4,SYBU,SLC11A1,EMC1,STX1A,JMJD6,VAMP1,TRPM2,PLPPR2,SLC26A10,NT5M,SEMA3B" Drug 6290_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NDRG2,ADGRF5,APAF1,DDO,PDE8B,LDLRAD4,BTRC,CACNG1,RAB33A,SULT4A1,ABCG1,CSF1,NCAN,SRGAP3,DTNA,EFNA3,PLXNC1,IRAK4,COQ7,DMTN,EPHB1,TRMO,PNMA2,USP19,ZNF276,GPR17,STON1,GRM1,HSF2,IL6ST,ITIH2,KIF5C,GIT1,ZNF862,CLDN11,RAB3A,TMEM206,FBXW7,TCP11L1,NTNG1,RPH3A,KIF13A,RBM34,SS18,NACAD,MAPK8IP3,PHLDB1,ARHGEF9,KIAA1107,PCDHA6,ZFPM2,TIAM1,TLR4,LMF1,LAT2,MVB12B,AAAS" Drug 4076_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "PLA2G6,MRTFA,BEGAIN,APBB1,ZSCAN18,BMP7,FUBP1,IL33,BTRC,CACNA2D1,CAMK2B,SCARB1,CDH8,AKAP6,CRY2,CSF1,CSF1R,CTNND2,RIMS3,SPOCK3,EDIL3,CEND1,HPCAL4,AGAP2,PDLIM5,PRELID3A,RND1,GNAL,GPR17,NXPH3,ITPKA,KHK,LSS,ADAM22,NPTX2,NRCAM,NTRK2,PDE4B,ENPP2,PLCD1,NECAB2,POU3F2,PTCH1,PTPRB,GAL3ST4,RFX2,RGS12,RNASEL,RPH3A,ZNF334,SNAP25,ZHX3,SYT11,ARC,GPR161,ZNF24,SLC17A7" Drug 2449_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NDRG3,ADRA1D,AMH,APOC1,APP,CASK,NCOA1,SCAPER,ARHGAP33,PLAA,CLCN4,NMT2,CLTB,IQCK,SLC4A7,DAPK3,CTIF,EFNB3,LRRC23,FHL1,FOXG1,CINP,GABRA2,GATM,SRCAP,SPACA9,NCKAP1L,MEF2C,CNOT4,SLC11A2,NUCB1,NUMA1,CDK14,SLC25A23,ZCWPW1,ZNF493,TMEM206,EMID1,MRAS,EPN2,SLC20A2,MAPKBP1,DOP1A,EMC1,SPTAN1,FCHO1,EXOC7,PDLIM2,ADGRL3,SYNE1,OBSL1,CHST8,KCTD2,RBFOX2,LMF1,MAP3K12,TIGD6" Drug 6188_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "TKTL1,ARID1A,ADORA1,APBB2,PPFIA3,CDK10,DDX3Y,BMP7,CACNB4,LARGE1,CNR1,CSF1,ARHGAP24,DAPK3,SPOCK2,DLG3,CDON,DPP6,DTNB,HIPK3,VPS13B,RASGRP2,TLR7,SEPT9,HNMT,KCNJ5,KHK,MDM4,MMP17,ADAM22,MYBPC1,NEUROD2,NF1,NTRK2,PFKFB2,RETREG1,CNTLN,NKAIN1,RGS4,RGS12,PNMA8A,PRR5L,ZNF821,SH3BGR,SH3BP2,FNDC3A,SLC11A1,SOX10,ARHGAP26,SS18,RPRM,VGF,ZNF24,SCG2,NAV2,ST7,PHTF2" Drug 5748_UP Butacaine [149-16-6]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "AQP4,ARSE,N4BP2L1,LDLRAD4,CACNA2D1,SLC16A4,LHX2,HOMER3,AKAP6,COL9A3,NCOR2,ABCG1,AATK,SPOCK3,SV2A,DTNA,PLXNC1,NCALD,IGSF6,CDKL3,CORO2B,DLC1,FGF12,C1orf61,PRELID3A,HBS1L,ATP8A2,SRCAP,GPR22,GSTM5,LMO1,SMAD1,CD200,TAGLN3,MYL3,NF1,NPPA,NTRK2,CDK18,PRKCB,MAPK7,PTN,ACSS3,RASA3,SH3BP2,DOCK10,DZIP1,EFHD1,WDTC1,SS18,SYN2,CUX2,R3HDM1,PIK3R5,TPM1,KCNAB1,MVB12B" Drug 3059_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADCY6,SLC12A5,MTUS1,SEMA6A,ANK2,ANK3,BMP7,BTRC,TMEM257,CRLF1,NRXN2,DNAJB5,RAB26,HAPLN1,MFAP3L,C2CD2L,USH1C,HEYL,EPB41,FAM198B,AFF2,CHL1,SRCAP,GLI2,PCSK1N,GRIK1,GRIK5,GRIN2C,KLF12,IL6ST,KIF5C,NEUROD1,NOVA2,NTRK3,OPCML,OXTR,MAPK7,RELN,BCAS3,PTH1R,PTPRH,GAL3ST4,SEC61A2,SEMA6D,SH3GL3,SLC1A3,SMTN,SOX15,HECW1,TACR1,SMG6,TCF7L2,PHF24,HIF3A,AP4E1,TIAM1,ZNF154" Drug 4748_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "LTBP4,ANK1,APBA2,AZGP1,NRP2,CACNA1G,NEURL1,AATK,RIMS3,RASGRP2,MTSS1L,ZNF391,ETV1,CEND1,NRN1,FAM198B,TUBB4A,CAMSAP1,EFCAB2,B3GAT1,ZNF44,SIGLEC8,TOX3,GPER1,GRIK5,GRIN2C,IL12A,KCND3,KCNJ5,KHK,LMO1,SMAD1,AFDN,PACSIN1,RAD52,RGS12,EMID1,KCNIP2,SCN8A,BCAN,SLC1A2,SLC2A5,SOX2,IQSEC2,ACSBG1,ATP11A,TAL1,ARHGEF12,TGFBR3,DAAM2,TPM3,TRPM2,VIPR2,SPHK2,REEP1,SEMA3B,KCNAB1" Drug 1463_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "NME5,LTBP4,ALK,CDC42BPA,KCNAB2,CDK13,SLC4A4,ADGRB3,ARHGAP33,SDC3,NOS1AP,EDIL3,LRRC23,STX2,F3,TUBB4A,CAMSAP1,DCTN2,ERAP1,GLYR1,POLL,CNTRL,CACFD1,GRM1,WIF1,HLF,ITIH2,KCNH2,KCNQ3,MBD1,KITLG,NFYA,RETREG1,PACSIN1,RELN,EMID1,SH3BP2,ZNF365,SLC2A5,PPP4R3A,MAPKBP1,SNCA,SOX2,SPTAN1,MAPK8IP3,PHLDB1,ARC,PSD3,CRTC1,CABIN1,TPM3,CHST5,TUBB1,SLC30A3,PRDM2,MPPE1,SENP7" Drug 3326_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADORA2A,APLP1,PPFIA3,ATM,SCAPER,MTMR3,BTRC,CA4,CBFA2T2,FOXN3,ASIC3,B4GALT6,NMT2,CREM,PPP6R2,DCAF4,SMG7,SLC12A6,ATN1,DSCAM,DTNA,SUGP2,EIF5,ING4,STX2,TXNL4A,GLS,GNG4,CNTRL,BTN2A1,KCNH2,KCNJ5,NPTX1,MBOAT7,PRKAR1B,GRAMD1C,PRODH,RGS12,SH3BP2,SYBU,SMARCA4,ZHX3,IQSEC2,SS18,PHLDB1,PLCB1,SEMA4A,KIAA1107,TCF7,TMEM121,SLC44A1,UBTF,VIPR2,KCNK12,XRCC4,ST7,RNF170" Drug 6006_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "FAM131A,APOC1,CDK13,EIF4G3,GYG2,KRIT1,ZFYVE9,QKI,HOMER3,CREM,EPB41L2,ZNF589,FGFR3,SEMA4D,GABRA2,TXNL4A,RAB30,RAB40B,TDRKH,GPR19,GRB10,NR3C1,MAP4K5,INPP5B,ITPKB,KIF5C,LIG4,MAP4,MITF,SETD4,PMP22,PRPH,GON4L,TMEM104,ATG16L1,RNASEL,SGK1,ZFP30,SH3BP2,ITSN1,FAM214B,SLC15A2,MAPKBP1,ZHX3,IQSEC2,MAPK8IP3,TTBK2,VAMP1,PLCB1,ASTN2,TRIM2,ARHGEF12,AHCYL2,ZKSCAN5,ZFP37,REEP1,GDPD5" Drug 4067_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "DPF1,ADRA1D,APP,SLC4A4,ADGRB2,NRP2,GYG2,CAMK2B,SCARB1,NEURL1,KCNAB3,CBARP,TAOK2,SLC24A2,VAX2,IFFO1,CSF1R,RGS6,PLCH2,ARHGEF4,CTNND2,RIMS2,RIPOR2,DTNA,TENM1,ING4,ELAVL3,ETV1,PIPOX,FABP7,CSPG5,MCHR1,CACFD1,KCNN1,KIF5A,VWA5A,MARK1,MMP16,NF1,PCBP3,NTRK2,DDR2,PIK3CD,PTN,SH3BP2,NTNG1,ZNF334,KIF13A,IZUMO4,HECW1,ARHGAP26,PLCB1,TEX15,AP4E1,CDK20,SPHK2,KCNAB1" Drug 4143_UP Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "AQP4,AQP6,ATP2B3,CFLAR,BAIAP3,CDH10,CHN2,CLCN4,AKAP7,CTIF,MYEF2,DMPK,RCAN2,F5,FGF1,FGF14,CAMKK2,OGA,ZNF44,GABRB1,GPR162,GFER,GNAO1,GPER1,GRM7,GUCY1A2,HMX1,IRF8,KCNMA1,KCNN1,AFDN,CD200,ADAM22,TAGLN3,MX1,SLCO1C1,PAH,RETREG1,NECAB2,GDPD2,PTAFR,PTPRB,SUGCT,MYH14,CNKSR2,SLC8A1,MAPKBP1,KDM4B,COLGALT2,SYN2,POPDC3,ADGRL3,KIAA1107,SEZ6L,AMOT,NT5M,NLRP3" Drug 1633_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "AMPH,APC,APLP1,SEMA4G,PLA2G4C,DNAH17,MARK4,SLC4A4,ARHGEF7,BTRC,CA12,B4GALT6,TAOK2,HOMER3,PHF20L1,EGR3,SORBS3,CEND1,OGA,GPM6A,NR3C1,HNMT,ICA1,IL6ST,MGAT3,MPP2,PDPK1,PPP5C,PTAFR,PEX5,RAD52,ZCWPW1,GTDC1,RGS10,RGS12,ROM1,TCP11L1,RPS6KA2,SGK1,SH3BP2,SYBU,ANKRD6,WDTC1,SOX2,ZCCHC24,KDM4C,NSFL1C,VPS13A,PLCB1,WSCD1,RPGRIP1L,DOCK9,ARHGEF12,KAT6B,VGF,HPS4,RNF170" Drug 6675_DN Suloctidil [54063-56-8]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADD2,NME5,PLA2G6,ALK,APAF1,APC,BRINP2,HOMER3,IQCK,ABCG1,PDE4DIP,RASSF2,GIT2,EDIL3,CELSR3,PLXNC1,DENND4A,ETV1,RRAGB,SCML2,ZNF589,FGFR1,ANKFY1,DENND2A,B4GALNT1,USP19,KCNMB4,GPD2,GPER1,IL6ST,VWA5A,MDFI,TM6SF1,MIA2,NF1,PIK3R1,PLXNB1,GRAMD1C,SNRK,PTCH1,ELOVL2,FAM184A,ROM1,SBF1,ATXN7,ASAP3,RPH3A,PREX2,BTBD7,TNIK,COLGALT2,TMEM121,NACC2,KLC2,XRCC4,EMSY,SEMA3B" Drug 6004_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ACHE,LTBP4,FAM135A,CDC42BPA,KCNAB2,ARHGDIG,PLA2G4C,BAIAP3,CACNA1D,CDH10,TBRG4,CACNA2D2,CHM,FAM189A2,QKI,WHRN,CSF1,VCAN,DNAJC6,KLHL3,DMPK,EDNRA,EFNA3,C3orf18,VPS13B,TUBB4A,ST3GAL6,FER,OGA,GAB1,DISC1,SOX21,ATXN2L,TJAP1,INPP1,KIF5A,VWA5A,MAP2,MSI1,PAX6,PDE3B,LRP12,PPARA,RPS6KA2,WLS,SCN8A,ITSN1,BTBD7,DOP1A,INKA2,VPS13A,TMOD1,RUNDC3B,TRPM2,UCHL1,VAV2,EVI5" Drug 3904_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "DPF1,NLGN4X,AMPD3,APAF1,APC,APOC1,AQP4,PRX,PDE8B,BRINP2,KSR1,CACNA1I,CFAP410,NRXN3,ARHGEF6,FAM149A,CRYM,MICAL2,KIAA0586,SPOCK2,RUSC2,EDNRB,C3orf18,SPEG,KIAA1109,CAMKK2,GPR162,GLYR1,POLL,GOLGB1,TDRKH,GRIK5,KCNJ5,MATN3,AFDN,NNAT,NOVA2,LRP12,POU3F2,MINDY2,PRKCB,RPS6KA2,ZNF821,PKNOX2,ARHGEF40,CXXC4,SNAP25,SOX2,SOX15,THSD1,MAPK8IP3,PHLDB1,DMXL2,TEX15,HEY2,SPHK2,NUP214" Drug 4532_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ACHE,SLC12A5,PPFIA4,NCOA1,RGS9,BMP7,BAIAP3,CACNA2D1,HAP1,SEPT7,CHI3L2,CHRNB2,CTNND2,CX3CR1,MYEF2,RABGAP1L,ST8SIA3,EDN1,EDN3,EPB41,FGF1,HPCAL4,FYB1,ERAP1,PRUNE2,HSD17B1,KCNC1,KIF5C,MDM4,ADAM22,NELL2,NOVA2,PDE2A,CCSER2,NECAB2,RASGRF1,TMEM206,NEK11,SCN2A,RASA3,FRMPD1,BCAN,SLC12A4,SCN3B,SOX2,TNIK,TROVE2,ACSBG1,VAMP1,THRA,UGT8,VIPR2,VLDLR,ZIC3,SLC30A4,MAP3K12,EVI5" Drug 6624_DN Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASIC1,TRMT9B,APBB2,APC,CDK13,DNAH17,KIF1A,MPDZ,CACNA1A,CBFA2T2,RAB28,SLC4A8,BAG4,CREB5,CSF1R,CNTNAP2,CTIF,CDON,TNK2,FGFR1,C1orf61,PDLIM5,FYB1,ZNF44,TRAF3IP2,DISC1,GPM6B,LPAR4,GRK4,GRM8,KIF5C,AFDN,SLC11A2,PPARA,MAPK7,SAMD9,FAM120C,RAB3A,RAB3IL1,FAM184A,ZCWPW1,RGS10,MYH14,RPS6KA2,ATXN7,FBXO11,BCAN,KDM4B,PDZD2,MAPK8IP3,RPGRIP1L,TK2,TRIO,WIPF1,XRCC4,SCG2,TIGD6" Drug 5337_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "AK2,ALCAM,APC,APLP1,MARK4,CACNA1I,C5,CACNG1,KYAT1,CNTN1,AKAP7,SLC4A7,HDAC4,MAML1,GIT2,DNM1,ING4,PLEKHO1,EPB41L1,F5,ZNF589,CAMKK2,OGA,BTN2A1,HNMT,KCND3,MAP4,MAPT,MITF,MPP2,NEK1,NF1,NPR2,PC,SSH1,NLE1,SAMD9,TMEM104,RIPOR1,RGS3,RGS10,RGS12,MYH14,CCDC25,BTBD7,SMARCC2,KDM4B,ZBTB43,CAMTA2,INKA2,EXOC7,TRIM2,PCDHGB6,ZNF34,TK2,XRCC4,NAV2" Drug 1482_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "PLA2G6,SPARCL1,CDC42BPA,CNTNAP1,ALDH4A1,SLC4A4,CACNA1I,BAIAP3,LDLRAD4,CALB1,SOCS6,CRMP1,VCAN,RIMS2,DCAF4,GPRASP1,CTIF,DYRK1A,EDNRB,EIF4G2,MTSS1L,NCALD,TUBB4A,FGFR1,C1orf61,IQCG,OGA,SEPT9,CPLX2,GLYR1,GRB10,GRIK5,NR3C1,GRM1,TJAP1,KCNH2,KIT,MBD1,MGAT3,NOVA2,MINDY2,PPP2R5C,PRKAR1B,SNRK,ZSCAN32,ZSCAN2,TCP11L1,ZNF821,MRAS,ASAP3,CNKSR2,EMC1,SPART,PLCB1,ARC,TMOD1,EPM2A" Drug 7071_DN CAY10397; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ABR,PLA2G6,PPFIA3,SEMA4G,ALDH4A1,ADAM15,BCL2L2,CFLAR,SYNJ2,ARHGEF7,MYRF,AP4M1,PLAA,RAB26,CSF1,VCAN,SDC3,ZNF337,TBC1D5,SGK2,FCF1,EFNA3,BAIAP2,ANKFY1,PDLIM5,INPP5K,SRCAP,USP19,GLRB,AGBL5,SHISAL1,IL11RA,NFYA,PDE1C,CDK14,CCSER2,PLEC,MAPK7,GRAMD1C,SEC61A2,MCMBP,ITSN1,PPP1R9A,ANKRD6,SHANK2,COA1,SMARCA4,RCOR3,THSD1,NXT2,VPS13A,SYT1,FRYL,LMF1,ZNF32,ZBTB38,PCBP4" Drug 4256_UP Tocainide hydrochloride; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ACTN2,NDRG2,SLC12A5,ADORA1,NME5,LTBP4,SEMA7A,PKP4,APAF1,GAS7,PPP4R4,ATP1A2,N4BP2L1,ATP6V0A1,NRP2,MTMR3,NCOR2,SUSD5,CNTNAP2,MAML1,CTIF,SRGAP3,EXOG,DRD1,EDNRA,IRAK4,SRPK3,NCALD,IGSF6,ZNF391,FGFR1,AGAP2,ATP8A2,GATM,TDRKH,GRIK5,GRIN1,ELOVL5,ITIH2,LSS,MAN2A2,NPTX1,DCHS2,PTPRN2,ZMAT4,RET,MYH14,SALL1,SYP,ASTN2,ADGRL3,SMG6,CRB1,AP4E1,TPM1,ZNF24,DPF3" Drug 2242_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ASIC2,NME5,MRTFA,APBA2,AQP4,PDE8B,CADM3,ADAM23,CFAP410,RUNX1T1,CDH8,CDO1,CHM,TCEAL2,RIPOR2,DAPK1,RUSC2,DRD1,EDNRA,LRRC17,FGF12,FLNC,SORBS1,OGA,RND1,GPD1,NR3C1,KCNH2,MDM4,MEF2C,MOBP,NTRK2,NTRK3,TREM2,PACSIN1,MAPK7,MAPK10,FAM120C,SH3BP2,SH3GL2,ASAP3,NLGN1,SLC9A5,CXXC4,LIMCH1,PEG10,ZNF423,SPTB,SPART,EPB41L3,AJAP1,POPDC3,SMG6,PSD3,TEX15,DICER1,WNK1" Drug 7355_UP Harpagoside [19210-12-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "PLA2G6,C1QTNF3,BEGAIN,AMPD3,APAF1,APBA2,ATP6V0A1,MPDZ,SYNJ2,SCAPER,BAIAP3,BTRC,CA4,SRSF11,B4GALT6,FADS2,HOMER3,FAM169A,GREB1,ARHGEF4,DNAJC6,RABGAP1L,ING4,DENND4A,EZH1,OGA,GNG4,SPACA9,CACFD1,ELOVL5,HNMT,KCNH2,KCNJ3,MEIS2,MMP16,PDE3B,GTDC1,ZNF821,FAM214B,SHANK2,SLC22A4,SMARCC2,LIMCH1,RBM34,KDM4C,MAPK8IP3,PHLDB1,ARHGEF9,PLCB1,WSCD1,AHCYL2,BEX4,PRDM2,HPS4,NUP214,ACTR3B,SSPN" Drug 3402_UP Primidone [125-33-7]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.63E-06 1.29E-01 5.57E-05 6.34E-04 57 199 "ADCY2,NME5,SYT13,APOC1,CACNA1I,CCKBR,GPR37L1,CHRNA4,CLTB,IFFO1,CPS1,SNCAIP,ARHGEF10,SPOCK2,DBT,RUSC2,EXOG,ATN1,DUSP9,SGK2,FRY,PLXNC1,ELAVL3,HSD17B14,LRRC17,ERCC2,REEP2,CAMKK2,DLL3,NEU3,GNAO1,GPM6A,GRM7,C2orf72,KCNMA1,PCBP3,CLDN11,PDE2A,LRP12,C19orf57,PTHLH,RAD52,SYNDIG1,RYR1,RPH3A,TSNAXIP1,VAMP1,ARC,ATP11A,WSCD1,THRA,PARD3,SEZ6L,TRO,TRPC1,TRPM2,EPM2A" Drug 1745_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.66E-06 1.30E-01 5.63E-05 6.41E-04 50 167 "ADD3,BIN1,FAM131A,DNAH17,RASL11B,CFLAR,CD86,CD38,CHN2,ZFYVE9,CREM,SIPA1L1,PPP1R16B,CTNND1,DOCK4,ZFYVE16,FAM13A,KAT8,BAIAP2,PRKAG2,C1QL1,MALT1,PTPRT,ADAMTS6,AFF1,OLR1,PDE4B,PDE4D,PIK3R1,GPSM2,SMOX,PTAFR,CCDC40,SATB1,ATXN2,SGK1,NTNG1,ZC3H13,BEX1,SPTAN1,SAMSN1,EPB41L3,PLCB1,CAMSAP2,TCF4,SZT2,SLC44A1,TPM4,WNK1,CAMK1G" Drug 4998_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.75E-06 1.35E-01 5.81E-05 6.61E-04 55 190 "RGS20,MARK4,DDX3Y,CDH10,CLGN,CHI3L2,ASIC3,CNN3,ARHGEF6,SNPH,MFAP3L,ATN1,RCAN1,SIDT2,C3orf18,HSD17B14,VPS13B,FHL1,OGA,GFER,RND1,GLYR1,PRUNE2,GPR22,PCLO,GSN,INPP5B,KCNJ5,KCNMA1,KCNN1,KITLG,MID1,AFF1,CD200,P2RY13,LRRN3,ELOVL2,RAB3IL1,RPH3A,LIMS2,PKNOX2,SNCA,IZUMO4,ST5,CEP68,PLCB1,ARC,TNS1,TRIO,TRPC1,VAV2,KCNK12,MAP3K12,SEMA3B,KCNAB1" Drug 2465_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.75E-06 1.35E-01 5.81E-05 6.61E-04 55 190 "NDRG2,APAF1,KCNAB2,APBB2,ADAM15,BACH1,CANX,CCNT1,PLAA,CLCN3,TPP1,QKI,VCAN,EDRF1,RABGAP1L,DTNA,HIPK3,FCF1,VPS26C,PTK2B,KAT8,ZNF589,KIAA1109,FHL1,EFCAB2,CELF1,GALC,INPP5K,TJAP1,ITGAM,MDM4,AFF1,NEK1,PKN2,RAD52,RGS10,CLIP1,ATXN1,SLC2A5,CCDC88A,SLC11A1,SLC20A2,TROVE2,SS18,JMJD6,ARHGEF9,ARHGEF12,AHCYL2,DICER1,TMPO,TRPS1,FLRT2,LAT2,REEP1,SYNC" Drug 5802_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.84E-06 1.39E-01 6.00E-05 6.83E-04 53 181 "ABAT,ADRB2,NME5,EPB41L5,ARNTL,MARK4,BRINP2,ADGRB2,ST3GAL5,NEURL1,WHRN,ABCG1,PDE4DIP,CTH,DNAJC6,JAKMIP2,PLPPR4,EDN1,EFNA3,RGS17,TAOK3,SORBS1,PNMA2,FYN,RND1,GLS,STON1,GSN,KCNH2,KIF5C,VWA5A,MEF2C,MMP16,TAGLN3,PCDH9,PDGFRA,PFKFB4,SERPINI1,PTCH1,ENOX1,RGS4,SH3GL3,WDR47,BEX1,THSD1,ELOVL4,RGL1,SYT11,SYT1,COBL,TGFBR3,DNAJC12,PLSCR4" Drug CID000447081 1m5b Stitch 2.89E-06 1.41E-01 6.09E-05 6.93E-04 8 9 "CACNG2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRM3" Drug CID006324635 LY339434 Stitch 2.89E-06 1.41E-01 6.09E-05 6.93E-04 8 9 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5" Drug CID005311255 Ly294486 Stitch 2.89E-06 1.41E-01 6.09E-05 6.93E-04 8 9 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3" Drug CID000114827 LY354740 Stitch 2.90E-06 1.42E-01 6.12E-05 6.96E-04 22 51 "BSN,CACNA2D1,STX2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,KCNJ3" Drug 4829_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "PDE8B,NRP2,FOXN3,TPP1,NECTIN3,SPOCK2,RUSC2,MAGI2,EGR3,PLXNC1,ELAVL3,VPS26C,RRAGB,FGF13,HBS1L,ALDH1L1,PRUNE2,GPM6B,ATF7,ICA1,JAK2,KCNK1,KIF5C,KPNA5,MEF2C,BCO1,NELL2,ENPP2,CDK14,SERPINE2,PLCD1,PACSIN1,PPP5C,PTHLH,RGS12,KLHDC8A,SEMA6D,SYBU,PKNOX2,SNCA,KDM4B,CDK19,CLSTN2,SS18,AJAP1,ARC,WSCD1,TRIM2,PCDHGA10,DOCK9,AP4E1,FAM155A,LAT2,ZFP37,ZBTB14,MKRN3" Drug 3941_DN Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "NDRG2,AP2A2,DOC2A,APBA2,APLP1,CDK10,ARHGDIG,CDK13,BCL7A,LDLRAD4,CA4,CBFA2T2,CDC42,ZFYVE9,CLTB,SDC3,MAML1,PARD6A,DNM1,CDON,ATN1,EDNRA,EFNB3,LRRC23,RASGRP2,PIPOX,EZH1,KIAA1109,FHL1,KHDRBS3,DLL3,SRCAP,USP19,CNTRL,MSR1,ZNF862,NPY,CLDN11,PLXNB1,MAPK7,MAPK8,PTN,RAB3A,RALGDS,WLS,SH3BP2,BCAN,ST5,ARC,CABIN1,TRPC1,HIRA,MICAL1,LAT2,ZIC3,SPHK2" Drug 3718_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "PLA2G6,C1QTNF3,AMT,GAS7,APOC1,CDC14B,CDK10,ADGRB2,NRP2,IL33,CACNA1A,CACNA2D2,CHRNB2,NCOR2,ABCG1,CSNK1E,CNTNAP2,CTNND2,DAPK3,CHRDL1,DMPK,DTNA,HIPK3,ING4,MRNIP,HSD17B14,FGF1,FOXG1,C1orf61,PRELID3A,SCIN,INPP5B,MAN2A2,MX1,NELL2,NPR2,RETREG1,CEP41,PRKAR1B,MAPK8,WDR25,ATXN1,ZNF821,AMBRA1,ZNF415,TNIK,ZHX3,KDM4C,DDN,SYT1,TBCEL,SZT2,TK2,LMF1,TRIM9,NT5M" Drug 5774_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "AP2A2,DOC2A,PPFIA4,EPB41L5,ATP6V0A1,LDLRAD4,RUNX1T1,USP2,FOXN3,CHRNA4,TAOK2,STOML1,HOMER3,CNTFR,PDE4DIP,ST18,SV2B,EDIL3,CELSR3,COQ7,ZNF391,EZH1,ZIC4,PDLIM5,B3GAT1,GATM,SRCAP,CSDC2,GPD1,PRUNE2,GRIK2,SPACA9,GRIK5,CACFD1,GRM2,IGF1,VWA5A,MSI1,ADAM22,TAGLN3,NRCAM,PFKFB4,PID1,C1orf54,TMEM206,SLC11A1,TNIK,HECW1,NFASC,RPGRIP1L,OBSL1,TPM1,CHST5,ZMYND8,AMOT,SENP7" Drug 4291_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASIC1,ADGRF5,APC,SEMA4G,PPP4R4,NRP2,CAMK2B,CDC42,ASIC3,TAOK2,TCEAL2,HAPLN1,FAM131B,TM9SF4,GIT2,ARMCX2,RUSC2,ATN1,SUGP2,EGFR,LPAR6,SORBS3,IRAK4,ING4,CDKL3,PTK2B,FGFR1,SESN1,POLL,SOX21,SHISAL1,ADAM22,NF1,NUCB1,OPCML,PALM,PLXNB1,RIPOR1,RAB3IL1,ACSS3,SEC61A2,SAFB,PREX2,SMTN,ZHX3,SPTB,TROVE2,SAMSN1,SS18,KIAA1107,TNS2,CRTC1,GPR161,SEMA3B,URM1,SENP7" Drug 4326_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "DOC2A,PDE8B,ARHGEF1,SYNGR3,ARHGAP33,TAOK2,CLCN4,LY86,PICK1,NRG2,CRMP1,CSF1R,VCAN,PDE4DIP,SPOCK2,CHRDL1,DMPK,ATN1,MBNL2,MRNIP,TUBB4A,FGFR1,SEPT9,POLL,GPER1,TJAP1,IL6ST,INPP5B,KIF5C,MEF2C,LYRM9,NUCB1,NLE1,MAPK3,ELOVL2,PID1,ZDHHC14,RGS10,MCMBP,SBF1,IL17RB,ASAP3,SLN,BEX1,ZBTB43,LHPP,MAPK8IP3,MLC1,ZEB1,TK2,RPRM,PLPPR2,VIPR2,ZNF45,KCNAB1,PHTF2" Drug 5056_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASPHD1,APAF1,SEMA4G,PRX,SLC4A4,FUBP1,CACNA1G,LDLRAD4,SYNGR3,PICK1,IQCK,WHRN,CABP1,RGS6,CTIF,DBT,MAGI2,DUSP9,ST8SIA3,SIDT2,PLXNC1,ELAVL3,MTSS1L,FGF1,GAB1,GFER,GNG4,LPAR4,TPPP,ADAMTS8,GRM7,LIFR,LSS,MAPT,NTRK3,OPRL1,PAH,CAMKV,DCHS2,PTPRH,PID1,RGS10,TCP11L1,ATXN1,ASAP3,DOCK10,SLA,SLC4A3,ZBTB43,DDN,MAPK8IP3,PHLDB1,SLC44A1,CHST5,TRPC3,WNK1" Drug 3522_UP Imidurea [39236-46-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASIC1,KLRC4,NME5,ASCL1,ATP2B2,CADM3,RGS11,SYNJ1,CFAP410,CACNB2,HAP1,ARHGEF2,CLTB,CNN3,AKAP7,AKAP6,TCEAL2,CPS1,NCOR2,PHF14,SEC14L5,DCC,KLHL3,DMPK,ELN,HSD17B14,MTSS1L,ERCC2,DKK3,HPSE2,TJAP1,IL6R,KCNH2,KCNMA1,MPP2,BCO1,TAGLN3,NOS1,KCNK10,SMOX,LRRN3,MAPK7,SAMD9,FAM120C,CCDC40,CPEB3,NTNG1,ST6GAL1,SHANK2,PLCB1,PCDHGA10,DOCK9,SLC35G2,ZFP37,SLC17A7,NUP214" Drug 2189_UP Acacetin [480-44-4]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ALK,CNTNAP1,PRX,PLA2G4C,BMP7,FUBP1,CACNA1I,LDLRAD4,CFAP410,SLC16A4,CDC42,CDH2,CREM,ABCG1,DZIP3,CTNND1,DNAJB6,E2F5,ANKRD46,SORBS3,CDKL3,SH3YL1,FLT1,GLYR1,GRIN1,RNFT2,HAS2,IL12A,KIF5A,AFDN,CD200,MT1M,ZNF862,SMIM7,CEP41,SYTL2,WDR25,RPS20,PAQR6,SCG5,SH3BGR,MYH15,HECW1,ZBTB43,SPART,PHLDB1,JMJD6,TMEM151B,RALYL,TF,CBX5,RUNDC3B,FAM155A,FLRT1,PRDM10,KCNAB1" Drug 4262_DN Tolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ADCY6,MTUS1,PDE8B,ST3GAL5,SCARB1,CDC42,CHN2,RAB26,HOMER3,WHRN,VCAN,PDE4DIP,FAM169A,SLITRK5,RIMS3,RUSC2,PLPPR4,DYNC1I1,DPH1,EFNA3,PLXNC1,ETV1,EFEMP1,FGFR1,TRMO,PRELID3A,GABRA2,DENND2A,HNMT,SHISAL1,DIPK1A,LIFR,LIG4,MIA2,TAGLN3,MTR,NDP,PAK3,CCSER2,PLCD1,PRKAR1B,PRPH,PTPRN2,FAT4,FAM184A,ZDHHC14,FBXW7,SCG5,FNDC3A,SLC4A3,NCDN,ARHGEF12,TPM2,WIPF1,NSD2,KAT6A" Drug 6135_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ADCY6,ADORA3,DOC2A,BIN1,CDC42BPA,FGD2,BCAS1,KIF1A,BCL7A,LDLRAD4,CACNB4,HAP1,RUNX1T1,CD38,CDH2,CDO1,RIMS3,DGKG,SV2A,ATN1,CNNM1,OPTN,AGAP2,PDLIM5,CAMKK2,CPLX2,SCIN,KCNJ5,MMP17,TAGLN3,EPN1,VPS13C,PTCH1,RFX2,MYH14,ST6GAL1,SLC6A7,SHANK2,SMARCD3,TMCC1,KDM4B,IZUMO4,HECW1,PCDHGA1,PHF24,PSD3,AHCYL2,TMOD1,SEZ6L,TPM1,AMACR,ZBTB16,SLC17A7,KCNAB1,CAMK1G,TIGD6" Drug 2126_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASIC1,KCNAB2,APBB2,STX16,CHI3L2,ASIC3,RAB33A,CLU,DNAJB5,PDE4DIP,CNTNAP2,SNPH,DUSP9,SIDT2,PLEKHO1,STX2,EZH1,FGF1,FGFR1,DLL3,GRM8,ICA1,JAK2,KCNN1,KIFC3,LMO2,GIT1,SLC11A2,PAK3,PBX1,RC3H2,PRKAR1B,PRPH,BCAS3,PEX5,RGS4,NUDT11,KIRREL1,STUM,DOCK10,BTBD7,SNCA,FNBP1,ERC1,ZBTB43,LHPP,SMG6,SYNE1,ARHGEF12,TPM1,VGF,WNT7A,ZBTB38,PRDM2,PARP6,NUP214" Drug 4260_DN Picrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "MTUS1,C1QTNF1,APBB2,SHROOM2,DNAJB5,HOMER3,WHRN,CPS1,PDE4DIP,CNIH3,DYNC1I1,DPH1,EDN1,ING4,PLEKHO1,COQ7,STX2,DENND4A,SPEG,ETV1,FGFR1,RUNDC3A,GLI2,KCNMB4,GPER1,BACH2,DIPK1A,TM6SF1,MIA2,TAGLN3,NDP,PDGFRA,PIK3R1,RETREG1,RC3H2,PRPH,PTPRN2,TMEM231,RAD51D,RALGDS,FAM184A,TRAPPC13,CSRNP3,FBXO11,SLC1A3,LIMCH1,WDTC1,ARHGEF9,TCF7L2,ARHGEF12,ZNF34,SSBP2,UGT8,WIPF1,EMSY,KCNAB1" Drug 2538_UP Sulfapyridine [144-83-2]; Up 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "C3orf14,NR0B1,C1QTNF3,BIN1,ASPA,CFAP410,CACNA1D,MAP7,B4GALT6,CHRNB2,FAM149A,SLC4A8,CRY2,CHD5,RIMS3,DCT,DLG3,DLG4,EXOG,TRAPPC9,DSCAM,TNK2,DMTN,CACNG2,FOXG1,NBEA,GAD1,SIGLEC8,AHDC1,CSDC2,GPR19,GRIN1,GRM1,LSAMP,MATN2,MPP2,MSR1,ZNF862,PDE4D,MTRF1L,PTAFR,RASGRF1,PRR5L,ZNF821,RASA3,SMTN,TMCC1,PEG10,SPTAN1,CDK19,TCF7L2,PSD3,ICAM5,RUNDC3B,REEP1,SLC30A4" Drug 3829_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "KIDINS220,TRMT9B,KCNAB2,PPP4R4,PLA2G4C,CHRD,CADM3,KSR1,SLIT2,RAB33A,ZFYVE9,SULT4A1,CNTN1,CSF1R,DAPK1,DAPK3,SPOCK2,CNIH3,DRD1,EDIL3,SGK2,CALCRL,ERCC2,PTK2B,FGFR1,C1orf61,CAMKK2,CSPG5,GAD2,TMEM8B,GDF9,HPGDS,GPM6A,GRIK1,INPP5B,KCNJ3,LSS,MOBP,NF1,NNAT,PCBP3,OPRL1,GPR85,CDIP1,PPARA,RFX2,KCTD17,CAND2,CRTC1,TF,DAAM2,VAV2,LAT2,PRDM10,PARP11,NLRP3" Drug 4557_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "GRAMD1B,AP2A2,APAF1,SLC4A4,ADGRB3,CFLAR,SYNJ2,GYG2,C5,IL33,HAP1,MAP7,CBFA2T2,PLEKHB1,WHRN,ABCG1,CSF1,CTH,ARHGAP32,PITPNC1,SV2B,SRGAP3,ATN1,ING4,ELAVL3,ETV1,SORBS1,FYB1,GAB1,SRCAP,GPER1,JAK2,LIG4,MMP16,ADAM22,NOVA2,OPCML,PDE3B,PDE4B,PDE4D,PLCD1,SMOX,GRAMD1C,PTHLH,PTPRH,RAB5B,GAL3ST4,FAM214B,RIMS1,HECW1,ARHGAP26,ATP10B,EPB41L3,TCF4,R3HDM1,TPM1" Drug 2180_UP Heliotrine [303-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "SLC12A5,BEGAIN,BIN1,ANK3,CNTNAP1,CDK10,ARHGDIG,SLC4A4,FGF17,GYG2,CFAP410,MAP7,EPS15L1,CTNND1,MFAP3L,ST8SIA3,CNNM1,PLXNC1,SORBS3,STX2,ST3GAL6,GAA,GLRB,KCNMB4,GPM6B,PCLO,GRIK5,GRM1,HSD17B1,HTR2A,KCNMA1,KIF5A,MOBP,NPR2,OPRL1,P2RY1,PCDH9,PMP22,MASP1,SYTL2,TTLL7,PNMA8A,ZNF821,STUM,CPEB3,PKNOX2,SNAP25,SPTB,NPAS3,SPART,CLSTN2,STX1A,KIAA1107,TJP1,RUNDC3B,PARP11" Drug 7326_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASPHD1,ABHD6,SLC12A5,NME5,APAF1,APBB2,PDE8B,SLC4A4,ATP2A2,CADM3,KIF1A,SCAPER,BTRC,ZFYVE9,PICK1,NCOR1,FAM169A,MFAP3L,C2CD2L,GNE,EGFR,MRNIP,ERCC2,EZH1,ACSL4,SORBS1,DISC1,ALDH1L1,MSL3,GNG4,CNTRL,GRM8,GUCY1B1,ATXN2L,INPP5B,KPNA5,MIA2,MYT1,NF1,SLC11A2,PIK3CD,MAPK7,GON4L,SBF1,SYBU,SMARCD3,SNCA,RBM34,SOX3,TCF7L2,SIK3,DICER1,AP4E1,TMOD1,KLC2,SSPN" Drug 3843_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ASIC1,ACTN1,NDRG2,AP2A2,CDC14B,SPTBN4,CAMK2B,CCNT1,CDH2,LHX2,EPS15L1,CLCN4,TMEM59L,PICK1,WHRN,CRY2,RIMS3,DAPK3,CTIF,TMCC2,EFNB3,ING4,ERCC2,SPEG,ATP8A1,ANKFY1,CAMKK2,FUT9,NEU3,SRCAP,C1QL1,GLYR1,POLL,GNG3,GPD2,GRIK5,GRIN1,GSN,KCNK2,LSS,MAOB,KITLG,AFDN,NF1,NUMA1,PPARA,SELL,RPH3A,COA1,SNCA,PEG10,ZC3H13,ATP11A,GPR161,DAAM2,TTPA" Drug 2425_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "SEMA6A,SYT13,CDC14B,BMP7,HIP1R,LARGE1,CHRNA4,RAB26,COL9A3,CSF1,PDE4DIP,USP6NL,TOX,DMD,MBNL2,CALCRL,ERBB2,CDHR1,BAIAP2,HPCAL4,ZNF44,B4GALNT1,SIGLEC8,SEPT9,POLL,GNAS,HPCA,KCNMA1,MAPT,MID1,AFDN,MMP16,MYO6,CAMKV,PLP1,PROX1,PTPRB,MYH14,NEK11,S100B,FRMPD1,PKNOX2,WDTC1,MAPK8IP3,DNMBP,RPGRIP1L,PCDHGB6,TK2,TLL2,AMACR,OSBP2,VAV2,SEMA3B,KCNAB1,PLSCR4,CAMK1G" Drug 6689_DN Biotin [58-85-5]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "APP,CDC14B,MARK4,KIF1A,ST3GAL5,CACNA1A,KRIT1,ABCG2,ARMC8,BAG4,VCAN,SGSM2,CHRDL1,FAM13A,COQ7,CDKL3,FGFR1,AFF2,OGA,FYN,B4GALNT1,POLL,GNG4,GPM6B,LPAR4,KLF12,ICA1,KCNN1,SCAMP5,NUMA1,PALM,PIK3R1,RETREG1,PTN,ZSCAN2,ROM1,NEK11,RXRA,ASAP3,FBXO11,NLGN1,MYH15,SPTAN1,IQSEC2,MAPK8IP3,SUPT5H,ROBO3,DOCK9,AHCYL2,TK2,WIPF1,WNT7A,XRCC4,SH3GLB2,KCNAB1,DPF3" Drug 4251_DN Antipyrine [60-80-0]; Down 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "PLA2G6,APOC1,ATP1A3,KIF1A,ADAM23,ADGRB2,CFLAR,MYRF,CBFA2T2,TAOK2,RAB26,AK5,ATN1,DTNA,EFNA3,EGFR,MBNL2,PLXNC1,HSD17B14,COQ7,MTSS1L,ST3GAL6,ZNF589,FOXG1,SEMA4D,ANKFY1,FYN,ZNF44,RUNDC3A,GLS,GPD2,LPAR4,GUCY1B1,KCNN1,PALM,PLXNB1,PPP5C,PRKAR1B,ELOVL2,PTPRB,FRMPD1,FAM214B,ZNF667,IFT122,DOK5,IQSEC2,SS18,ASTN2,TEX15,TPM2,VAV2,LMF1,REEP1,TFIP11,WNK1,KCNAB1" Drug 3268_UP Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "NDRG2,NME5,DOC2A,TRMT9B,BIN1,APC,PPP4R4,ARRB2,SLC2A11,ALDH7A1,ST3GAL5,BAIAP3,BTRC,HAP1,NEURL1,RCBTB2,PICK1,CNTFR,CNTN1,WHRN,SDC3,GIT2,DMPK,TOM1,ACSL4,SEMA4D,ALDH1L1,C1QL1,ICA1,KCNH2,KCNN1,VWA5A,MDM4,MGAT3,ZNF862,NUMA1,P2RX7,CNNM2,RGS10,KCTD17,SLC6A8,SLC11A1,INKA2,ABCC8,ARC,SZT2,TEX15,TRO,PLPPR2,VLDLR,ZBTB14,SPHK2,SLC17A7,KAT6A,SSPN,SENP7" Drug 7452_UP Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "NDRG2,AK2,PLA2G6,SEMA6A,LTBP4,APOC1,SEMA4G,CDK13,ALDH4A1,KIF1A,SCAPER,SGCE,CNTFR,DCT,HS3ST2,ATN1,SGK2,VPS13B,MTSS1L,DLC1,KAT8,FGFR1,C1orf61,PRELID3A,OGA,ALDH1L1,GRM8,ITGA7,MAP2,MDM4,MGAT3,MPP2,SLCO1C1,PPP2R2B,PROX1,PRPH,PTAFR,RGS12,PAQR6,CLIP1,SLC2A5,SLC6A9,SOX10,SPTAN1,ATP10B,ST5,MAPK8IP3,WSCD1,KIAA0930,TNS2,SPX,TMOD1,CDK20,TRH,GDPD5,KAT6A" Drug 4015_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ADCY6,PKP4,BCAS1,PPFIA3,AQP4,ADAM23,CFAP410,CDC42,ARHGAP33,ZFYVE9,VAX2,CNTFR,AKAP7,TCEAL2,ATRNL1,CTH,HDAC9,MYEF2,ST8SIA3,ATP8A1,FGFR1,DCTN2,OGA,GAB1,HBS1L,ERAP1,NEU3,IL6ST,SMAD1,MDM4,MSR1,NCAM1,NDUFA5,NPTX1,PDE4D,PRPH,PTPRN2,BEND5,RFX3,PNMA8A,MRAS,DOCK10,SNCA,KIF21B,SPTAN1,TPM1,CHST5,TRIO,CADM1,VGF,VIPR2,LAT2,MAP3K12,PARP6,DPF3,JPH3" Drug 4220_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "MTUS1,ANK3,PDE8B,ST3GAL5,C5,CDC42,NMT2,ARMC8,BAG4,ENTPD4,PDE4DIP,TBC1D5,DBT,CNIH3,MFAP3L,PLPPR4,PARD6A,FCF1,EPHA5,ZNF391,ETV1,RRAGB,ZNF589,GLRB,MSL3,TDRKH,DIPK1A,MBD1,MIA2,TAGLN3,NDP,CLDN11,ENPP2,RETREG1,SYTL2,RAD51D,FAT4,BEND5,RGS10,MYH14,SUPT20H,FBXO11,ST6GAL1,NLGN1,SLC20A2,LIMCH1,CDK19,VAMP1,TCF4,THRA,VGF,WIPF1,NSD2,ZNF711,MPPE1,PHTF2" Drug 2776_UP Aconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ADORA1,SYT13,KCNAB2,DDO,APOC1,PPFIA3,PPP4R4,ALDH4A1,SLC16A4,CHN2,FADS2,AKAP5,RIMS3,SPOCK2,DNAH9,DYNC1I1,SLC12A6,ST8SIA3,PLXNC1,SPEG,DLC1,GAD2,DISC1,PCDH17,TDRKH,IL6R,LAMA2,MAN2A2,MOBP,NF1,NPPA,CLDN11,PLCB2,MINDY2,CEP41,PTHLH,CCDC40,RNASE1,PPP1R9A,BCAN,ARHGEF40,SLN,SPTB,CLSTN2,SSTR2,NCDN,POPDC3,ATP11A,TCF7L2,CRTC1,CHST8,THBS4,TK2,HIRA,FAM155A,DNALI1" Drug 4552_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "DPF1,PLA2G6,MRTFA,AMT,ATP6V0A1,SCAPER,MTMR3,GYG2,TMEM257,NRXN2,NRG2,CTNND2,NOS1AP,FRMPD4,DAPK1,SPOCK2,DCC,C2CD2L,MAGI2,IRAK4,ING4,RCAN2,ETV1,FGFR1,HPCAL4,AGAP2,ERAP1,SIGLEC8,RUNDC3A,GLYR1,ADAMTS13,ATXN2L,ICA1,ITGA7,KCNN1,KPNA5,MAG,MGAT3,LYRM9,NF1,PC,PDE3B,PDE4D,SPATA6,POLG,CNNM2,PTPRH,PTPRN2,KCNIP2,ZNF423,NPAS3,CEP68,VAMP1,TEX15,SSBP2,NUP214" Drug 3423_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-06 1.44E-01 6.12E-05 6.96E-04 56 195 "ABR,SEMA7A,APAF1,APBB2,APC,APOC1,CDC14B,ARHGDIG,ASPH,BTRC,CACNB2,CAMK2B,NEURL1,FOXN3,TPP1,CNTNAP2,DCAF4,DMPK,DRD1,DTNA,OPTN,ELN,SCML2,ZNF589,FHL1,DPYSL4,GAD1,GALC,GLS,NR3C1,KCNN1,MEF2C,MIA2,CNOT4,NPR2,PDE3B,CEP41,PRKAR1B,RAB3IL1,ZDHHC14,RGS12,MYH14,SHANK2,ZKSCAN3,CDK19,IQCE,PCDHA6,TMOD1,PARD3,TNS1,TRPC1,LMF1,ZIC3,PRDM2,ITM2C,PHTF2" Drug ctd:D016627 Oxidopamine CTD 2.94E-06 1.44E-01 6.12E-05 6.96E-04 49 163 "ADORA2A,SEC11C,AIFM1,CNR1,CYBB,DLG4,DRD1,DNM1L,ABCC9,RASGRP1,EN2,EPHB1,PPP1R1B,NSG1,GAD1,GAD2,GFAP,GRIA2,GRIN1,NR3C1,GRM1,HSPA1L,IDH3A,KCNJ11,MAPT,NFE2L2,NOS1,NPY,OPA1,OPRL1,PDYN,PENK,SH3KBP1,MAPK3,MAPK8,MAPK9,RET,ATXN2,SLC1A2,SLC1A3,SNCA,SPP1,ABCC8,TAC1,SIRT1,TNFRSF1B,TRH,UBC,UCHL1" Drug CID000122150 saclofen Stitch 3.04E-06 1.49E-01 6.33E-05 7.20E-04 20 44 "ABAT,ADORA2A,CACNA2D1,CP,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3,PRIMA1,SLC6A1,SLC6A11" Drug 3902_DN Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.06E-06 1.50E-01 6.36E-05 7.24E-04 54 186 "ADD3,CDC7,APBB2,GAS7,APLP1,CDK10,CDK13,ATM,AKAP12,SIPA1L1,PDE4DIP,DZIP3,GREB1,EDRF1,ZNF804A,LYPD1,ATN1,DSCAM,DLC1,SCARA3,OGA,GHR,RUNDC3A,GPR19,STON1,GPR37,BRINP3,ITPKB,JAK2,KCNJ3,LMO2,MEIS2,MMP17,NUMA1,PDE3B,PDE4A,PLCD1,PPP5C,PKIA,PRKAR1B,MAPK8,PTHLH,FAM120C,SLC1A7,LIMCH1,WDTC1,NXT2,TACC1,MCF2L,TCF7L2,ARHGEF12,SLC44A1,ZIC3,ITM2C" Drug 1664_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.06E-06 1.50E-01 6.36E-05 7.24E-04 54 186 "NDRG2,AMPD3,ANK3,APBB2,MARK4,CFLAR,HIP1R,PLEKHB1,NMT2,SH2B1,FEZ1,CSNK1E,GPRASP1,GIT2,LYPD1,DSCAM,FCF1,ING4,LRRC23,EXTL2,EZH1,INPP5K,RAB40B,TDRKH,GPR19,STON1,LMO2,ZNF862,RETREG2,MAPK8,PTCH1,PTPRE,MYH14,CCDC25,PCMTD2,EMID1,FNDC3A,RAB3GAP1,KDM3A,CDK19,THSD1,CEP68,TACC1,TRIM2,SZT2,FRYL,TK2,BEX4,TRPC1,VGF,SPHK2,EMSY,MPPE1,UBE3B" Drug 2919_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "SEMA7A,RGS20,ALDH4A1,ATP2B2,NRP2,LDLRAD4,BTRC,CFAP410,CACNB2,HIP1R,CHN2,SULT4A1,RAB26,CABP1,FAM169A,CTNND2,SEC14L5,PHYHIP,SPOCK3,DTNB,SORBS3,CDHR1,ETV1,F5,CAMSAP1,PRELID3A,GABRA2,GPR162,PCDH17,GRIK1,GRIN1,MGAT3,CD200,NOS1,NRCAM,OPCML,CLDN11,PGAM2,EPN1,POU6F1,LRRN3,NKAIN1,RAB3IL1,CCDC40,GTDC1,RAVER2,TCP11L1,EMID1,SH3BP2,SLC11A1,PDZRN3,DOK5,CDK19,VAMP1,SYT5,RBFOX2,PCBP4" Drug 6106_UP "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "RALGAPA1,BEGAIN,ARHGDIG,ALDH7A1,NRP2,SCAPER,CACNA1I,BRSK2,CCKBR,CHM,DNAJB5,LY86,SLC4A7,SEC14L5,RASSF2,PARD6A,EDNRA,EFNB3,TENM1,ING4,ELAVL3,RRAGB,TBR1,NEU3,ALDH1L1,PRUNE2,TDRKH,PCLO,SMAD1,MPP2,NF1,CLDN11,PCDH9,PDZRN4,LRP12,POU3F4,PRKCB,MAPK8,PROX1,GDPD2,TRIM68,RGS7,RGS12,KCTD17,TCP11L1,DOCK10,SLA,SLC11A1,PDZD2,RGL1,ATP11A,KIAA1107,DOCK9,TNS2,PCDHA6,TLL2,UBE3A" Drug 3008_DN Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "BRAP,AP2A2,ANK3,APBB2,ATP2A2,NRP2,KSR1,SLC16A4,SCARB1,CHM,CHRNA4,CLCN4,PDE4DIP,CTNND1,ZNF337,BRINP1,KIAA0753,DYRK1A,EEF1A2,MBNL2,EPB41,PIPOX,PRKAG2,EFCAB2,SEPT9,ADAM28,GPM6B,ITGAM,KPNA5,LSS,MAP4,AFDN,NINJ2,NPR2,OLR1,ZSCAN32,GTDC1,PLPPR3,FRMPD1,AMBRA1,NLGN1,EPN2,SLC20A2,SNAP25,EMC1,MLC1,SYT5,KAZN,CAMSAP2,IQCE,TCF4,OBSL1,THBS4,TNNT1,RBFOX2,LMF1,PHTF2" Drug 3222_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ARID1A,NME5,APC,GAS7,CDC14B,CACNA1I,CFAP410,CA4,CACNB4,CCKBR,CDH8,RAB28,FHL5,COL9A3,NCOR2,SIPA1L1,ARHGEF4,NOS1AP,ARHGAP24,SPOCK2,MFAP3L,DMPK,TNK2,VPS13B,IGSF6,ANKMY1,HPCAL4,IQCG,PRELID3A,GABRA1,GALC,ADAMTS13,KCND1,KCND3,KCNMA1,MEF2C,MMP16,GIT1,NNAT,PLEC,RGS12,RPS6KA2,SLC2A5,SLC6A8,SLN,SNCA,EMC1,ARHGAP26,NPAS3,INKA2,ARC,ADGRL3,SZT2,CABIN1,TRPC1,CLIP2,GDPD5" Drug 6095_UP Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ADORA3,C1QTNF1,BEGAIN,BIN1,PLA2G4C,CCDC181,SEPT7,LY86,IFFO1,ABCG1,KLHL3,SPOCK3,ST8SIA3,FAM13A,AASS,ELAVL3,CACNG2,GABRA2,GPM6B,LPAR4,GRK4,GRIA4,GRM1,SOX21,ADAMTS6,IRAK3,KCNH2,NCF2,NEK1,NEUROD2,NPPA,PCBP3,NTRK2,OLR1,CLDN11,PHKG1,SERPINE2,PNMA3,MAPK8,PROX1,RELN,SAMD9,ZSCAN32,PTPRB,CCDC40,KCTD17,TCP11L1,SLC2A5,SNCA,SPTB,NPAS3,SPART,TK2,HEY2,SPHK2,ITM2C,PHTF2" Drug 7463_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "SEMA6A,DOC2A,NCOA1,N4BP2L1,BCL7A,CFAP410,HAP1,CBFA2T2,CLTB,SULT4A1,NCOR2,GPRASP1,TBC1D5,TRAPPC9,E2F5,OPTN,RBM12,EFNB3,EIF5,MRNIP,ELN,DMTN,GABRA2,GAD2,SRCAP,MALT1,COPS8,GRB10,RNFT2,INPP5B,MAP4,MIA2,KITLG,GIT1,NF1,PLXNB1,PRKAR1B,WDR25,PTN,ZSCAN32,RIPOR1,RGS12,KANSL3,SLC11A1,SNCA,HECW1,TROVE2,VAMP1,MCF2L,WSCD1,TRIM2,TIAM1,TK2,R3HDM1,PIK3R5,KCNK12,TFIP11" Drug 6894_UP SB 203580; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ASPHD1,LTBP4,APP,CDK13,DNAH17,MAGI1,CRLF1,RAB28,PICK1,CNTFR,CREB5,JAKMIP2,RUSC2,SGSM2,ARNT2,DSCAM,DTNA,ABCC9,FEM1B,FCF1,EFNA2,YAF2,MBNL2,ETV1,CSPG5,SIGLEC8,ADAMTS13,GRIN1,CACFD1,BACH2,MDFI,MMP16,MN1,MX1,MYO6,MYT1,NCAM1,PBX1,GPR85,PFKFB2,PLXNB1,PTAFR,PTPRB,PEX5,RAD51D,C1orf54,KLHDC8A,TMEM206,DGLUCY,SEMA6D,ARHGAP26,SPTB,RPGRIP1L,TNS1,PDIA2,ZBTB14,NLRP3" Drug 3640_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "SYN3,NDRG2,MRTFA,ANK2,CDC14B,SEMA4G,MARK4,ASTN1,ATP2B2,CACNA1D,HIP1R,CCNT1,DLGAP1,GPR37L1,CHI3L2,B4GALT6,CLCN4,NMT2,TCEAL2,HDAC9,CTIF,BRINP1,ELMO1,RABGAP1L,SGK2,DMTN,RASGRP2,MTSS1L,ERBB4,FABP7,FGFR3,FOLR2,GFER,RND1,IL1RAPL1,ATXN2L,SHISAL1,ITGA7,KIF5A,NF1,NUMA1,TREM2,PIK3CD,PPARA,CNNM2,PTH1R,TTLL7,RAVER2,SEMA6D,SNCA,HECW1,HIF3A,TRH,TRPC3,CA14,UBE3A,PRDM2" Drug 416_DN clozapine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "AK2,LTBP4,GAS7,DGKD,PDXK,ASCL1,SLC4A4,FUBP1,CA4,RUNX1T1,NEURL1,SLC24A2,CPS1,CDC42BPB,CRMP1,ECE2,DAPK3,DSCAM,E2F5,USH1C,SGK2,FAM13A,ABI2,CALCRL,TUBB4A,TRMO,OGA,TMEM8B,NR3C1,BTN2A1,RNFT2,SCIN,NF1,OPCML,CAMKV,RETREG1,ZSCAN32,SEC61A2,GSTCD,TCP11L1,SYNDIG1,SLA,ELMO2,CDK5RAP2,ZSWIM8,NMNAT2,SPART,VPS13A,KAZN,TRIM2,VIPR2,ZNF189,ZNF195,MVB12B,EPM2A,CAMK1G,AAAS" Drug 3385_DN Nizatidine [76963-41-2]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "AP2A2,LTBP4,APBA2,PDE8B,CFLAR,SYNJ1,GYG2,CACNA2D2,ABI3BP,RIMS3,JAKMIP2,PARD6A,EDNRA,OPTN,PLXNC1,EIF4G2,DLC1,RND1,SPACA9,GRM7,ATXN2L,ELOVL5,IGSF1,IL6R,KHK,MAPT,MOBP,NOS1,NRGN,PALM,PDE3B,PDE4A,CDK14,NLE1,PTPRO,RAB3A,RAB3IL1,RAD52,RALGDS,C1orf54,RGS10,EMID1,RASA3,CPEB3,PREX2,SLC9A5,SNCA,THSD1,FAM168A,TBCEL,SMG6,TMOD1,CDK20,ZKSCAN5,UCHL1,KAT6A,SSPN" Drug 6075_UP Delsoline [509-18-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "APAF1,PPP4R4,RGS20,N4BP2L1,BTK,GYG2,INA,CHM,SNCAIP,TENM4,SPOCK2,EDN1,FAM13A,LRRC23,ERBB2,ZNF589,FGFR1,CAMSAP1,OGA,HBS1L,SRCAP,C1QL1,RND1,GLYR1,GRK4,GRIK5,AP4S1,ATXN2L,HPSE2,ITPKA,KCNB1,KCNJ4,KCNK2,SMAD1,MAOB,CD200,NEFM,NOS1,NPTX2,KCNK10,SNTG1,PFKFB2,RETREG1,CEP41,MAPK8,RELN,RFX2,RGS12,RORB,RPH3A,SLC11A1,SPTAN1,AJAP1,TEK,PIK3R5,MICAL1,EPM2A" Drug 1526_UP Midecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ASIC1,ABHD6,TRMT9B,AMT,APLP1,CDC14B,MARK4,FGF17,CFLAR,SYNJ2,CFAP410,ARHGEF2,SEPT7,SOCS6,RAB33A,PLAA,DNAJB5,FAM169A,RIMS2,HDAC4,MFAP3L,DRD1,PIPOX,FGF12,FOXG1,GPR153,INPP5K,MSL3,GNAS,MCHR1,PTGDR2,IL6ST,KCNJ4,KCNJ5,NEK1,NF1,NOVA2,CLDN11,PTHLH,ELOVL2,PTN,RAB3IL1,C1orf54,SH3BP2,PPM1E,FERMT1,DOCK10,SLC6A8,RBM34,WDTC1,ERC1,ARHGAP26,SZT2,TEX15,TNFRSF1B,WIPF1,DPF3" Drug 3503_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ACTN2,ADD2,SEMA6A,LTBP4,APBA2,APBB2,ATP1A3,ADGRB1,ARHGEF1,NEURL1,ARHGAP33,CACNA2D2,CHGB,AATK,CHD5,PDE4DIP,NOS1AP,SNPH,SPOCK2,ARMCX2,ATN1,DYRK1A,TENM1,CORO2B,AGAP2,ZNF44,GFER,GJB1,GPM6B,LPAR4,NR3C1,KLF12,ICA1,KCNH1,KPNA5,MAOB,ADAM22,MYH7,MYT1,NEUROD1,PDE4D,NLE1,PPP2R2B,MAPK7,PTHLH,RAB3IL1,RPS6KA2,SLC11A1,ZNF423,TROVE2,MAPK8IP3,TNS2,PCDHA5,AMOT,PDIA2,SLC13A3,SYNC" Drug 6826_UP Amrinone [60719-84-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ADCY2,AMT,EPB41L5,APLP1,APOC1,AZGP1,GYG2,SGCE,CACNG1,CLGN,ADGRG1,DNAJB5,CNTN1,WHRN,TCEAL2,NECTIN3,SPOCK2,CTIF,RUSC2,ATN1,ELAVL3,COQ7,ERCC2,CDKL3,KAT8,FGF13,HPCAL4,SEPT9,RUNDC3A,GPM6A,GRM1,AP4S1,HNMT,KIFC3,LSS,ADAM22,MX1,MYCN,NPPA,CLDN11,CDIP1,PPARA,MAPK7,PTHLH,FAM120C,C1orf54,CARF,SLCO1A2,MLC1,AHCYL2,HIF3A,THBS4,UCHL1,LAT2,ZNF23,NT5M,SENP7" Drug 2134_UP Sparteine (-) [90-39-1]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ADORA1,C1QTNF3,BIN1,APAF1,APP,FUBP1,BTRC,SOCS6,SPOCK2,SV2B,TRAPPC9,OPTN,EFNA3,FAM13A,MBNL2,VPS13B,STX2,CAMSAP1,FHL1,CAMKK2,GALC,ADAM28,ATF7,GRM7,PADI2,ICA1,TJAP1,IL6ST,KIF5C,MAP4,MEF2C,NUMA1,SERPINE2,SLC25A23,PPP2R2B,WDR25,PTPN13,ZFHX4,ANKRD6,SLC1A7,PEX26,RIMS1,SNAP25,PALLD,ARHGAP26,SPTB,TSPYL2,CEP68,CAMSAP2,TBCEL,AP4E1,KCTD2,SEZ6L,ZMYND8,FLRT1,LMF1,SLC17A7" Drug 5782_DN Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "C1QTNF1,APBA2,APP,ARNTL,NCOA1,ALDH4A1,CDK5R1,MAP7,CREM,DZIP3,ARHGAP32,DBT,SGSM2,DLG3,EFNA3,FAM13A,ING4,STX2,CAMSAP1,SCARA3,PRRC2B,GUCY1B1,SYNPO,TJAP1,MATN3,ZNF862,CNOT4,PBX1,MBOAT7,BCAS3,PTHLH,PTPRN2,RAD52,SH3TC2,FAT4,MYH14,FBXW7,ZNF671,SBF1,AMBRA1,ST6GAL1,KBTBD4,SMARCD3,LIMCH1,TROVE2,THSD1,SS18,FCHO1,MAPK8IP3,VPS13A,IQCE,ZMYND8,UGT8,LMF1,WNK1,NT5M,KAT6A" Drug 885_UP 5186223; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "ARID1A,BEGAIN,BIN1,DDO,CFLAR,BTRC,RHBDL1,USP2,SLC16A4,ARHGEF6,COL9A3,CTNND2,HDAC4,DBT,MFAP3L,EXOG,DTNA,HIPK3,RRAGB,F3,ZNF589,KIAA1109,FGF1,FGFR3,PDLIM5,ZMYND11,ADAM28,GPM6B,GPR37,FAM107A,AGFG1,TJAP1,ITGA7,KIF2A,MYCN,NPTX1,SNTG1,PLTP,TNPO2,RAD51D,RGR,RIT2,RNASEL,NEK11,WLS,RASA3,CHD9,ANKRD6,EPN2,FAM214B,ZNF423,SPART,ASTN2,TCF7L2,CHST8,TMPO,VAV2" Drug 6509_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "AK2,SYT13,AMPD3,APBA2,RGS20,PTCH2,ADAM15,CA4,CAMK2B,RUNX1T1,CBLN1,MTMR7,GPR37L1,SLIT2,AKAP7,WHRN,RCHY1,ARHGEF4,CTIF,HP1BP3,SV2A,EFNA3,AASS,SRPK3,ST3GAL6,CAMSAP1,POLL,GNAL,GNAS,GPER1,PCLO,ICA1,KPNA5,MATK,MBD1,MSI1,ENPP2,CAMKV,MTRF1L,PMP2,PROX1,PTCH1,ATG16L1,RASGRF1,RGS3,PNMA8A,TCP11L1,SLC2A5,ZNF415,MAPK8IP3,MLC1,SLC44A1,TLR4,PIK3R5,VIPR2,NSD2,ZNF711" Drug 5412_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.12E-06 1.53E-01 6.45E-05 7.33E-04 57 200 "NDRG2,AK2,PLA2G6,MRTFA,ARRB1,ATP2A2,BAIAP3,CFAP410,NEURL1,TAOK2,CLTB,CSF1,LRIG1,ARHGEF10,SDC3,CNIH3,DTNA,EFNB3,ELAVL4,MTSS1L,ERBB4,FECH,FHL1,PRELID3A,ERAP1,DISC1,SRCAP,GLYR1,CNTRL,NR3C1,GUCY1A1,KLF12,KCNJ4,KCNJ5,MX1,NOS1,PDE3B,LRP12,TNPO2,EMID1,RYR1,FBXO11,CNKSR2,SMTN,SLC6A8,SHANK2,SLCO1A2,HECW1,ARC,SYT5,POPDC3,KIAA1107,ZEB1,TMOD1,TRPM2,WIPF1,ITM2C" Drug ctd:D012524 Sarin CTD 3.18E-06 1.56E-01 6.57E-05 7.47E-04 75 286 "ACHE,ACLY,ADD1,ADORA1,ADORA2A,PLA2G6,APLP1,APP,ASCL1,DYNLL1,BCHE,CFLAR,MTMR2,CALB2,CALM1,RGN,PLAA,CLCN3,CLU,NCOR1,SOCS5,CST3,DBN1,RASGRP2,RTN3,TUBA1B,TUBB3,TUBB4A,GAP43,GFAP,GLS,GLUL,GNAO1,GNAS,STMN2,GRIK5,GSTM5,GSTT2,HP,IFI16,LAMP2,MAP2,MAPT,MBP,NACA,NEFH,NRCAM,NTRK2,NTRK3,OLR1,PCMT1,PFKP,ABCB1,SERPINI1,PLP1,PLTP,PMP22,PRKCB,PYGM,SLC6A15,RGS4,ZNF532,S100B,SGK1,SLC1A3,SNCA,STXBP1,SYT1,ZEB1,TF,KAT6B,TPM1,AMACR,UBC,LRP8" Drug CID000061605 Rubidium chromate Stitch 3.23E-06 1.58E-01 6.66E-05 7.58E-04 28 74 "SLC12A5,SLC24A4,ATP1A1,ATP1A3,ATP1B3,BLM,NAE1,SLC5A11,SLC24A2,SLC12A6,GYG1,KCNA4,KCNC1,KCND1,KCND2,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNK3,P2RX7,SLC12A2,SLC12A4,RIMBP2,SMUG1,TRH,SMARCAD1,WNK1" Drug CID000002653 AC1L1E5T Stitch 3.23E-06 1.58E-01 6.66E-05 7.58E-04 28 74 "ADCY2,ADCY5,ADCY6,ADCY8,NCOR1,NCOR2,DCT,AASS,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,TNFAIP8L3,NOS1,PLEC,PTAFR,SLC1A2,SLC1A3,SLC8A2,SLC12A2" Drug 6680_DN Strophantine octahydrate [11018-89-6]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.27E-06 1.61E-01 6.74E-05 7.67E-04 55 191 "ARID1A,CDC7,TRMT9B,APC,GAS7,SHROOM2,MARK4,OSGIN2,LRRFIP1,LHX2,SMARCAL1,DCAF4,CNIH3,KLHL3,RHOBTB1,EFNA3,EN2,ETV1,SEMA4D,FAM49B,PNMA2,SYT17,STON1,CNTRL,MUM1,ITPKB,MEF2C,MIA2,MN1,PDCD2,GRAMD1C,WDR25,PTPRE,PTPRN2,FAM120C,ATG16L1,BEND5,SUPT20H,ZFP30,DZIP1,ZNF365,WDTC1,COLGALT2,CEP68,ARHGEF9,PLCB1,KIAA1107,TIAM1,HEY1,TNS1,SMUG1,WIPF1,XRCC4,ZBTB14,PHTF2" Drug 3172_DN Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.27E-06 1.61E-01 6.74E-05 7.67E-04 55 191 "ASPHD1,ABHD6,TRMT9B,CDC42BPA,APC,APOC1,RASL11B,SLC4A4,ATP6V0A1,BCL7A,SYNJ2,ARHGEF6,CRY2,CYBB,GIT2,RABGAP1L,DTNA,TOM1,EDNRA,FEM1B,EFNA3,DMTN,CDKL3,CAMSAP1,ZNF44,TRAF3IP2,GRB10,RNFT2,HNMT,MEIS2,SCAMP5,MSI1,NNAT,SLC11A2,NUMA1,STRN3,POLG,PRKAR1B,RELN,GTDC1,EMID1,ATXN1,ZNF821,ZNF365,SLC20A2,VAMP1,ASTN2,TCF7L2,DOCK9,SLC44A1,TMOD1,CABIN1,UPF3A,PCBP4,TIGD6" Drug CID006435801 D-CPPene Stitch 3.30E-06 1.62E-01 6.80E-05 7.73E-04 17 34 "ADORA2A,CA4,DMTN,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 6701_DN Florfenicol [73231-34-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "PDE8B,MARK4,ALDH4A1,KIF1A,CFAP410,FOXN3,LHX2,AKAP7,IQCK,ARHGEF10,CNTNAP2,SDC3,RIMS3,SGSM2,CHRDL1,CELSR3,COQ7,SEPT9,MSL3,GPM6B,TDRKH,GRK4,GRM1,MMP16,GIT1,RETREG1,GRAMD1C,TMEM231,RAB3A,PID1,C1orf54,ZCWPW1,BEND5,KHDRBS2,FBXW7,TCP11L1,RXRA,FAM192A,SH3GL2,TNIK,SPATA7,BEX1,THSD1,CEP68,SYT11,KAZN,ROBO3,KIAA1107,TCF4,THRA,TNS1,LMF1,WNT7A,ZNF142,SEMA3B,KCNAB1" Drug 4406_UP "Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "SYN3,KIAA1324,BEGAIN,CDK13,ADAM23,CFAP410,RUNX1T1,INA,CLCN4,TPP1,STOML1,PICK1,CNTNAP2,SRGAP3,TNK2,PIPOX,EXTL1,SORBS1,FYB1,TMEM8B,ATP8A2,NEU3,GPM6A,GRM7,FAM107A,C2orf72,IL11RA,KCNMA1,VWA5A,AFDN,MYL3,NF1,NNAT,PDE2A,PENK,PFKFB2,PLCD1,PTAFR,ENOX1,ZNF493,RGS10,MRAS,SLA,ARHGEF40,IZUMO4,PEG10,ZNF423,INKA2,AJAP1,TCF4,HIF3A,TEK,TK2,SEZ6L,ADAMTS9,ITM2C" Drug 4574_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "RALGAPA1,ASPHD1,ADD2,C1QTNF3,PTCH2,CADM3,BMP7,FUBP1,MTMR3,BAIAP3,BTRC,KRIT1,USP2,NEURL1,CDC42,AKAP5,CREM,PDE4DIP,CNTNAP2,PHF14,CTNND2,PHYHIP,MFAP3L,C2CD2L,SRGAP3,RABGAP1L,AASS,MTSS1L,ZNF549,DLC1,ST3GAL6,FGF1,FGFR1,ZNF44,SIGLEC8,GPR17,AP4S1,ITGA7,MSR1,PALM,PDGFRA,EPN1,SPATA6,RGS4,RGS10,PNMA8A,ZFP30,TROVE2,MLC1,PCDHA5,TK2,CADM1,WIPF1,REEP1,ZNF225,PARP11" Drug 2310_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "GRAMD1B,NME5,KIAA1324,BEGAIN,BIN1,CDC42BPA,ANK1,ARSE,RASL11B,FGF17,CFLAR,KALRN,GPR37L1,CLCN4,SULT4A1,CNTFR,TCEAL2,NRG2,ARHGEF10,TOX,KLHL3,EDIL3,HIPK3,EN2,LRRC17,RASGRP2,ERCC2,SPEG,F5,ZNF589,AGAP2,DISC1,NXPH3,ITGAM,KCNMA1,LIG4,NNAT,NPTX1,OGG1,PCSK2,PDE4B,PIK3CD,CDIP1,PACSIN1,RAB3IL1,RAD52,SLC9A5,SHANK2,ATP10B,WSCD1,SLC35G2,TRO,VAV2,LAT2,SLC30A3,ST7" Drug 4151_DN Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADORA2A,LTBP4,ALK,MRTFA,APBB2,ALDH7A1,SYNJ1,BTRC,CFAP410,CAMK2B,ARHGEF2,ASIC3,CLTB,LY86,CNTFR,WHRN,CREM,SDC3,DCAF8,DYRK1A,MBNL2,OLFM1,FHL1,C1orf61,GAD1,SEPT9,ALDH1L1,GPER1,GSN,INPP5B,KCNJ5,MAPT,ADAM22,MX1,MYT1,NF1,NPTX1,P2RY1,PDE1C,PRKCB,KCNIP1,SH3GL3,PREX2,ARC,SYT5,POPDC3,TBCEL,CRTC1,THRA,HEY2,TPM2,TRPM2,FAM155A,UCHL1,VIPR2,PLSCR4" Drug 3042_UP Carbachol [51-83-2]; Up 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ABAT,ACHE,ABHD6,ADORA3,MTUS1,NR0B1,PPP4R4,ASCL1,RASL11B,ALDH4A1,AZGP1,MPDZ,CACNG1,USP2,INA,CHRNA4,CNTFR,NRG2,RGS6,RIPOR2,DCC,MAMLD1,DMTN,TBC1D16,FGFR1,C1orf61,FLT1,FYB1,RNFT2,GUCY1A1,PTGDR2,SCRG1,KCNJ5,KCNK1,MYH3,PRRX1,PID1,ROM1,SLC1A3,SMTN,SLC11A1,CLSTN2,ST5,TACR1,TCF7L2,PCDHGA1,PHF24,GPR161,TK2,TMOD1,TRPC3,UBE3A,FLRT2,VAV2,ZBTB16,STMN4" Drug 4182_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ARID1A,AMPD3,APBA2,GAS7,DNAH17,ALDH7A1,CFAP410,SLC16A4,CRLF1,FOXN3,CLCN4,SNCAIP,CSF1,SDC3,DAPK3,SPOCK2,SRGAP3,TMCC2,CDON,ATN1,SGK2,FEM1B,ERCC2,DLC1,ZNF589,FHL1,C1orf61,KHDRBS3,SEPT9,LYVE1,RND1,TXNL4A,RAB30,FERMT2,KCNN1,KCNQ3,SMAD1,MAPT,ADAM22,NNAT,PPP2R2B,SLC1A7,SLC9A5,SMARCD3,SNAP25,ZCCHC24,ZHX3,ZC3H13,NPAS3,INKA2,ARC,SYT5,WSCD1,TRO,TRPM2,PLSCR4" Drug 6782_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "RALGAPA1,ADORA2A,KIDINS220,AGT,ALCAM,AMPD3,APBB2,ALDH4A1,ATP2A2,ATP2B2,SGCE,LDLRAD4,CACNB2,CHRNB2,DNAJB5,SEC14L5,CTIF,BRINP1,RUSC2,EDN3,F5,FOXG1,FLNC,SORBS1,GAB1,ZNF44,GFER,MALT1,GRM1,KLF12,ITPKB,KCNJ5,LAMA2,VWA5A,MBD1,MSR1,ZNF862,PIK3CD,FXYD1,PTN,C1orf54,ZNF493,RGS10,TCP11L1,RYR1,PPP1R9A,ASAP3,SLC1A7,SLC11A1,SLN,CXXC4,ARHGAP26,PLCB1,SYT5,LAT2,KCNK12" Drug 7495_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ALAD,AMH,BIN1,APAF1,APC,ARRB1,STX16,ARHGEF2,PLEKHB1,CHRNA4,TAOK2,RIMS3,DAPK3,BRINP1,RUSC2,ATN1,RCAN1,CELSR3,EGFR,MBNL2,TENM1,STX2,ETV1,FGFR1,ANKFY1,GALC,SEPT9,INPP5K,GPM6B,SCRG1,DHX35,ICA1,KCND3,MAPT,NFYA,PFKFB2,MBOAT7,ZSCAN2,SUGCT,SH3BP2,FRMPD1,ASAP3,BCAN,PPP4R3A,MYH15,SP4,SPTB,CEP68,ATP11A,TRIM2,TRIO,TRPC1,SSBP2,PRDM2,SEMA3B,EPM2A" Drug 3690_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "GRAMD1B,APC,DDX3Y,SLC2A11,BMP7,MAP7,INA,CLU,RAB26,HAPLN1,LRIG1,CTNND2,ARNT2,EDN1,EGFR,ING4,SEMA4D,FLT1,FAM49B,GAB1,SIGLEC8,RND1,GNAL,GNG3,PTGDR2,KCND3,KCNMA1,KCNN1,KIFC3,LSS,CD200,LYRM9,PAK3,PALM,CDK18,PDE3B,PDE4B,PGAM2,SMOX,PNMA3,C19orf57,LRRN3,PTCH1,SUGCT,FOXRED2,SLC15A2,SOX2,SOX15,HECW1,MCF2L,DMXL2,ZFPM2,PIK3R5,LILRA4,VIPR2,SLC17A7" Drug 4446_DN 2-propylpentanoic acid; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADRA1D,BIN1,CDK10,MARCH3,ADAM23,SYNJ1,CBFA2T2,ARHGAP33,RAB28,NRXN3,PICK1,CSF1R,FEM1B,EIF4G2,ING4,STX2,FGFR1,PDLIM5,HBS1L,INPP5K,GNG3,GPM6A,GPM6B,KLF12,SCIN,KPNA5,MIA2,MN1,MSRA,MT1M,PBX1,PFKFB4,TNPO2,MINDY2,SAMD9,PTHLH,PTPRH,RGS4,TMEM206,MAP6D1,SBF1,ZNF821,SLC1A7,SNCA,EMC1,SPTB,COLGALT2,SAMSN1,COBL,DNAH7,TNS1,UBTF,VGF,WIPF1,ZNF24,TFIP11" Drug 2101_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ARID1A,MTUS1,MRTFA,APC,ALDH4A1,SLC4A4,ALDH7A1,HIP1R,SOCS6,ARHGAP22,ZFYVE9,CLCN3,ABCG2,RAB26,CSF1R,SLITRK5,PPP6R2,GIT2,SGSM2,DMPK,DTNA,ETV1,CORO2B,FGF1,GFER,GLRB,MSL3,STON1,PCLO,GSTM5,RNFT2,KCNN1,MEIS1,NFYA,PAK3,C1orf54,SUGCT,ZFP30,ITSN1,PPP1R9A,CCDC88A,TSNAXIP1,EMC1,ERC1,ARHGAP26,ZBTB43,INKA2,PHLDB1,COBL,IQCE,TCF7L2,RPGRIP1L,PCDHGA10,LAT2,KCNAB1,ADAMTSL3" Drug 2925_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ABAT,ALAD,APBB2,APC,CDK10,CDK13,MTMR9,C5,OSGIN2,CAPN3,KRIT1,CDC27,SOCS6,RCHY1,FEZ1,PDE4DIP,DCTN1,ZNF804A,DTNA,EGR3,EIF1,FYB1,ERAP1,LILRA2,ATXN2L,MAP4,MEF2C,RETREG1,SAMD9,SNRK,TMEM104,ZSCAN32,RET,DOCK10,FBXO11,ARFGAP1,ZNF667,MYH15,IZUMO4,ITPRID2,JMJD6,ATP11A,DNMBP,TBL1X,AHCYL2,ZMAT3,KAT6B,TNNT1,TNS1,TPM1,TPM2,SMUG1,UBE3A,SPHK2,WNK1,NT5M" Drug 2295_UP Riluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NDRG2,ADD2,ADORA1,SYT13,APBA2,APC,GAS7,ATP1A3,CALB2,CAMK2B,SEPT7,ARHGAP33,CHN2,WHRN,CABP1,COL9A3,IFFO1,CRMP1,ARHGEF10,DCAF4,SPOCK2,EDNRA,ING4,ERCC2,F5,TUBB4A,FGFR1,GPR153,GAD2,NEU3,GLS,GPR37,KLF12,HNMT,KCNB1,AFDN,ADAM22,NPPA,OPRL1,CLDN11,EPN1,RELN,KCTD17,SH3GL3,PEG10,SPTB,ACSBG1,SYT11,ARC,TBCEL,PCDHGA10,PCDHA5,ICAM5,FAM155A,WIPF1,ITM2C" Drug 5669_DN Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADCY6,AP2A2,APOC1,MARCH3,ALDH4A1,ATP6V0A1,BCL7A,CFLAR,BTRC,KYAT1,NMT2,HOMER3,PDE4DIP,ARMCX2,SMG7,TRAPPC9,OPTN,EFNA3,ING4,PLEKHO1,ANKMY1,FHL1,IQCG,TBR1,GLYR1,NR3C1,AGBL5,IPO5,MATK,MID1,ADAM22,NDUFA5,NEK1,PC,SNX10,PRKAR1B,PRPH,SNRK,TMEM104,RALGDS,FOXRED2,FUZ,AMBRA1,SLC1A7,BTBD7,LIMCH1,EMC1,ASTN2,EXOC7,AP4E1,HIRA,PLPPR2,ZBTB14,MAP3K12,PRDM2,EVI5" Drug 7338_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NME5,APAF1,ARRB1,KIF1A,CFLAR,CAMK2G,SLC16A4,CDC27,TAOK2,TPP1,HOMER3,AKAP7,DOCK4,FCF1,F5,DPYSL4,FAM49B,PRELID3A,GPR37,GRIK5,BTN2A1,KIF3A,PADI2,ATXN2L,HNMT,SMAD1,MAPT,MMP16,NF1,FAM120C,SBF1,ZNF821,RASA3,FNDC3A,SNCA,RBM34,ARHGAP26,ZNF302,ST5,TTBK2,AJAP1,VPS13A,POPDC3,TRIM2,PSD3,OBSL1,ZNF34,SLC44A1,TMOD1,R3HDM1,TRPC1,UBE3A,WNK1,HPS4,ACTR3B,SSPN" Drug 7400_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADGRF5,SYT13,SEMA7A,GAS7,APOC1,DNAH17,ASTN1,BAIAP3,FOXN3,CHN2,TAOK2,WHRN,SLC4A7,SLC4A8,NCOR2,CNIH3,MFAP3L,RUSC2,DLG3,EDN1,RASGRP2,OGA,ERAP1,SRCAP,ZNF276,LPAR4,GRK4,SHISAL1,IL12A,KCNJ5,MAG,MATN3,AFDN,CLDN11,PTHLH,RAD52,ARHGEF10L,FBXW7,TRAPPC13,MAPK12,SUPT20H,FBXO11,NLGN1,SLC1A6,SLC20A2,SLN,KIF13A,TSNAXIP1,TAL1,AP4E1,SSBP2,ZKSCAN5,VIPR2,XRCC4,UBE3B,DPF3" Drug 5253_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NR0B1,AMPH,APBB2,FAM131A,CDK13,ATM,SCAPER,NCOR2,ST18,DCAF4,RIMS3,MAML1,DAPK1,CTIF,SPOCK3,DMPK,ELAVL3,EN2,ST3GAL6,FHL1,DLL3,SIGLEC8,ALDH1L1,SRCAP,ADAM28,C1QL1,ATXN2L,KLF12,TJAP1,KCNN1,PPARA,FAT4,TRIM68,TTLL7,RYR1,MRAS,NLGN1,SLC1A7,SLC2A5,FAM214B,KANSL3,PKNOX2,COA1,KDM4B,IZUMO4,ZNF423,ARC,EXOC7,SZT2,CHST8,CABIN1,TRIO,TRPC1,FLRT2,SLC13A3,PRDM2" Drug 7531_DN 0393-0188; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "FAM135A,AMPD3,APOC1,SYNJ2,HAP1,CLGN,SOCS6,ATRNL1,EDRF1,CTIF,DCT,JAKMIP2,TRAPPC9,USH1C,DMTN,DLC1,CAMSAP1,FLNC,HBS1L,GALC,TMEM8B,SEPT9,LYVE1,GLS,NXPH3,ELOVL5,ITPKB,JAK2,TM6SF1,NELL2,SLC11A2,PALM,PCDHGC3,PCDH9,PDE3B,MINDY2,PPP5C,GDPD2,SNRK,TMEM104,PTAFR,RFX3,RGS10,KCTD17,TCP11L1,SGK1,SLC1A2,FAM214B,SNCA,TROVE2,RGL1,SZT2,BEX4,TRO,SPHK2,RNF170" Drug 2811_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ABHD6,MRTFA,CDC42BPA,APOC1,APP,ARHGDIG,ATP6V0A1,CFLAR,SCAPER,AKAP7,CLOCK,CRY2,LYPD1,DLG3,SIDT2,FGFR3,BAIAP2,TRMO,SRCAP,TXNL4A,PCSK1N,MUM1,HNMT,AGFG1,DHX35,IGSF1,INPP5B,JAK2,KCNH2,KCNJ3,KPNA5,LSS,MAP4,MITF,ADAM22,ZNF862,NACA,NEK1,SLC25A23,PRPH,TMEM104,ELOVL2,RGS10,ZNF331,AMBRA1,EPN2,SP2,CAMTA2,FCHO1,TBL1X,TCF7L2,KCTD2,VAV2,NDRG4,HPS4,ACTR3B" Drug 2958_UP Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADRA1B,MTUS1,CDC42BPA,KCNAB2,CDK5R1,SYNJ2,CFAP410,ZFYVE9,HOMER3,CREM,OSBPL3,PDE4DIP,ZNF337,SMG7,SV2B,RASGRP2,FGFR3,FHL1,AGAP2,PDLIM5,CAMKK2,GATM,ALDH1L1,PADI2,CD200,NEK1,NOVA2,SLC11A2,CDIP1,POU6F1,PTAFR,RAP1GAP,BEND5,PNMA8A,TMEM206,SEMA6D,ZNF821,RASA3,FAM102A,SHANK2,PALLD,TMCC1,TNIK,SPTAN1,EXOC7,PDLIM2,WWC1,SZT2,PCDHGA10,SYNE1,TNS1,RBFOX2,CHST5,UBTF,VAV2,ZNF142" Drug 7102_UP 0198306-0000 [212631-61-3]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ASIC1,ANK3,APBB2,APLP1,APOC1,PDXK,MARK4,ASPH,ALDH4A1,SYNJ2,CDH2,CDH8,CHD1L,CSF1,CSNK1E,PDE4DIP,SLITRK5,SDC3,RIPOR2,FEM1B,ING4,ATP8A1,FGF1,FOXG1,SEMA4D,CSPG5,GAD1,GPER1,KLF12,BACH2,HMGCL,ITIH2,KIFC3,LYRM9,ZNF862,NPR2,POLG,MED1,CNNM2,PTCH1,BEND5,SUGCT,SH3BP2,LIMS2,FAM214B,COLGALT2,ATP11A,WWC1,IQCE,TCF4,AP4E1,TK2,TPM4,LMF1,WNK1,MAP3K12" Drug 2631_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ADCY6,NME5,ALCAM,FAM131A,SEMA4G,MARK4,N4BP2L1,BAIAP3,CAMK2A,USP2,CDH8,CHN2,TAOK2,NDST3,DNAJB5,ABI3BP,MYEF2,RUSC2,RASL12,ZNF589,AMOTL2,TPK1,NSG1,GAD1,PCDH17,GNAL,GRK4,RASSF8,KCNA4,KCNN2,VWA5A,MDM4,ADAM22,NDUFA5,NOS1,ENPP2,PENK,PHKG1,PLTP,POLG,PPARA,PTAFR,RFX2,RGS10,SH3BP2,PREX2,SLC11A1,ZHX3,ARHGAP26,SPTAN1,PARD3,TRIO,ZMYND8,HIRA,FLRT2,MKRN3" Drug 4419_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "SEMA6A,APBA2,APBB2,GAS7,NUMB,SLC2A11,NEURL1,FOXN3,LHX2,AKAP7,WHRN,TCEAL2,CPS1,SEC14L5,RASSF2,SPOCK2,DMPK,HSD17B14,ERCC2,DLC1,FGF12,DPYSL4,SRCAP,GFER,ITIH2,KCNN1,MAP4,KITLG,MID1,MOBP,GIT1,ADAM22,NEUROD1,LRP12,FAM120C,RGS3,ASAP3,FAM214B,PKNOX2,CCDC88A,SLC11A1,KDM4B,PDZD2,IQSEC2,CLSTN2,RGL1,WSCD1,DMXL2,ZEB1,DICER1,TMOD1,R3HDM1,PIK3R5,FLRT2,VIPR2,PRDM2" Drug 3380_UP Carbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "DPF1,RALGAPA1,ADORA1,KIAA1324,FAM135A,APBB2,ATP2B2,CADM3,N4BP2L1,MTMR3,CA4,RUNX1T1,SULT4A1,CNR1,PDE4DIP,SPOCK2,DCT,TMCC2,ELAVL3,TNK2,ANKMY1,FABP7,ATP8A1,DISC1,MYOZ2,RUNDC3A,GRIK5,TJAP1,KCNJ5,KCNMA1,ADAM22,MX1,NNAT,NPPA,NPR2,PGAM2,PLXNB1,TNPO2,C19orf57,PPARA,WLS,SEMA6D,STUM,RPH3A,SLCO1A2,CXXC4,SOX10,ARC,ZEB1,SZT2,DOCK9,PIK3R5,TRPM2,VLDLR,MVB12B,PAK5" Drug 2280_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "AP2A2,ALK,RGS9,NRP2,SCAPER,CACNA1G,LDLRAD4,HAP1,CAMK2B,ASIC3,KIAA1549L,DNAJB5,CPS1,CSF1R,EDRF1,CTIF,NTM,MBNL2,IGSF6,DLC1,ZNF589,GABRA4,NEU3,RND1,GLS,HLF,C2orf72,ITGAM,ITIH2,KCNJ5,MAP4,MSR1,NF1,CDK14,PLCB2,PRKAR1B,PTCH1,CRTAC1,TCP11L1,ZFP2,FNDC3A,RIMS1,FAIM2,KIF21B,NPAS3,SAMSN1,MAPK8IP3,WSCD1,TF,CHST8,THBS4,SLC44A1,HEY2,RIMBP2,NT5M,DPF3" Drug 4647_UP Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "ASPHD1,ASIC1,MRTFA,GAS7,DDO,AQP6,PPP4R4,ASCL1,ATP1A2,SYNGR3,CHN2,NRXN2,PCYT1B,COL9A3,AKAP5,NCOR2,RGS6,PDE4DIP,NOS1AP,MFAP3L,DYRK1A,EZH1,CACNG3,FGFR1,FYB1,GABRA3,GAP43,SIGLEC8,GLI2,CACFD1,IRAK3,HLF,KCNC1,KCNF1,KCNH1,VWA5A,SMAD1,MATN3,MBNL1,MGAT3,NTRK3,PROX1,CNNM2,ZMAT4,MYH14,SLA,ARHGEF40,SNCA,SOX2,ZHX3,CLSTN2,SYN2,SEZ6L,NT5M,EPM2A,CAMK1G" Drug 425_DN staurosporine; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NDRG2,GRAMD1B,BEGAIN,APAF1,ARSF,ALDH4A1,STX16,CFLAR,HAP1,CHRM4,CNTFR,KIAA0513,DLG3,DSCAM,RASGRP1,EFNB3,EPB41L1,EPB41L2,TAOK3,FGFR1,FGFR3,AMOTL2,TRMO,POMT1,TBR1,NEU3,GHR,MCHR1,NR3C1,PTPRT,HPS5,SCIN,KHK,VWA5A,MAN2A2,MAPT,MBD1,MYO6,CCSER2,SYTL2,RGS12,ZNF821,PPM1E,SNCA,WDTC1,NMNAT2,GLT8D1,SRPK2,SS18,PLCB1,TMPRSS5,VAV2,NSD2,NDRG4,SLC26A10,CAMK1G" Drug 6591_DN PHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "APBB2,APOC1,CDK10,EIF4G3,ALDH7A1,ST3GAL5,LARGE1,FOXN3,RAB26,CREB5,ABCG1,AATK,DPH1,PTK2B,KAT8,FOXG1,TRMO,PDLIM5,GCNT2,GPR17,MAP4K5,BACH2,KHK,LIFR,MAPT,MT1M,MX1,PDCD2,PPP5C,PRPH,SAMD9,CYBC1,WDR25,PTCH1,PTPRH,PTPRN2,TMEM231,NEK11,FBXW7,AMBRA1,KDM4B,SPTAN1,LHPP,MAPK8IP3,PHLDB1,COBL,KAZN,PDLIM2,OBSL1,CHST8,TK2,CHST5,HIRA,XRCC4,NT5M,MVB12B" Drug 7025_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "KIDINS220,AP2A2,AK2,APLP1,ARHGDIG,SYNJ2,CA4,CACNA1D,PLEKHB1,B4GALT6,VAX2,PICK1,SLC4A7,BAG4,RGS6,LRIG1,HDAC4,CTIF,DMTF1,DTNA,LRRC23,CEND1,F8,FAM198B,DPYSL4,GRIA4,GRIK5,MUM1,IL6R,ITPKB,IPO5,LSS,MAP4,NASP,CNOT4,PRODH,DCHS2,SAMD9,VPS13C,CCDC40,KHDRBS2,FOXRED2,SH3BP2,FBXO11,PEX26,FAM214B,KANSL3,FAM168A,PLCB1,SYT5,PCDHA5,PIK3R5,UBE3A,KCNK12,HPS4,MARCH8" Drug 3171_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "AP2A2,AGT,FAM135A,ANK1,ANK2,KCNAB2,SPTBN4,ALDH4A1,CCDC181,ALDH7A1,SYNJ2,GYG2,CFAP410,HAP1,CLGN,CLIP3,AATK,IPCEF1,NOS1AP,DOCK4,TOX,DTNA,PLXNC1,SORBS1,PDLIM5,GATM,GPM6B,GUCY1A1,HLF,SYNPO,JAK2,KCNN1,MMP17,MSR1,ZNF862,NEUROD1,NOVA2,KCNK10,PLTP,NECAB2,PPP5C,PRODH,MASP1,SLCO1A2,SORCS3,TACR1,ACSL6,SZT2,DOCK9,R3HDM1,PDIA2,KCNK12,TFIP11,NT5M,NUP214,DPF3" Drug 2734_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "DNAH17,AZGP1,MPDZ,KSR1,CACNG1,THSD7A,BRSK2,MTMR7,CDH2,CDH8,CDH10,LARGE1,CHRNA4,TMEM59L,ABI3BP,CRMP1,HAPLN1,ARHGEF10,ST8SIA3,EDN3,SRPK3,FHL1,NSG1,GABRA3,ZNF44,SEPT9,GFER,GNAS,GRK4,ADAMTS8,SOX21,HTR5A,IGSF1,KCND3,KCNJ5,KCNK1,MBNL1,MGAT3,NOVA2,PCSK5,KHDRBS2,CCDC92,EPN2,KANSL3,PALLD,SYNE2,SYT5,IQCE,TIAM1,LILRA4,TRIO,OSBP2,XRCC4,CAB39L,FAM13C,JPH3" Drug 5510_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "AGT,AK2,SYT13,AMPD3,APAF1,DNAH17,CFAP410,CACNA1A,HIP1R,CBFA2T2,CDH10,PLEKHB1,CSF1,IPCEF1,RIMS2,TOX,SV2A,DTNA,MBNL2,LRRC17,KAT8,GABRA2,GPER1,ADAMTS13,ATXN2L,HNMT,KHK,MDM4,MOBP,NF1,PIK3CD,PTPRD,ACSM5,MARCH1,RALGDS,ATG16L1,CCDC102B,SCN8A,SH3GL3,FRMPD1,ST6GAL1,PKNOX2,BTBD7,SNAP25,KIF21B,PEG10,ARHGAP26,IQSEC2,STX1A,PLCB1,KAZN,KIAA0930,SEZ6L,XRCC4,PRDM2,NUP214" Drug 3401_UP Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NME5,MRTFA,BIN1,PDXK,RASL11B,ATP1A2,MTMR3,LDLRAD4,CACNA2D1,HIP1R,CDH8,PLEKHB1,TPP1,AKAP5,NECTIN3,VCAN,RASSF2,CNIH3,TMCC2,ST8SIA3,MBNL2,LRRC23,CEND1,FHL1,FOXG1,PCDH17,GPER1,GRB10,GRM1,GSN,ICA1,TJAP1,KCNMA1,LIFR,LSS,MX1,NELL2,TMOD2,CDIP1,SYNDIG1,WLS,SLC9A5,HECW1,SPTB,LMO3,JMJD6,VAMP1,SYN2,FAM189A1,TMOD1,LAT2,EPM2A,PHTF2,NUP214,ADAMTSL3,SENP7" Drug 1686_UP Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "TRMT9B,APC,ARHGDIG,SLC4A4,ADAM23,ARHGEF7,CACNB2,B4GALT6,RAB28,NECTIN3,DCAF8,TBC1D5,RABGAP1L,DMPK,NR1D2,DMTN,NCALD,FGFR1,PDLIM5,GPR153,ALDH1L1,USP19,GNG3,GPR19,GRIK5,KCNMA1,KCNQ3,MDM4,AFF1,NF1,NOS1,MAPK8,WDR25,ATG16L1,SEC61A2,GSTCD,RXRA,PPP4R3A,LIMS2,TNIK,TSNAXIP1,KDM4C,INKA2,STX1A,PLCB1,POPDC3,FBXW11,SZT2,THRA,TK2,TRIO,LMF1,SPHK2,SLC30A3,PRDM2,PHTF2" Drug 6021_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "LTBP4,DOC2A,BIN1,APP,PPP4R4,ASCL1,CCDC181,CADM3,SYNJ2,CA4,AATK,EDN3,COQ7,OLFM1,BAIAP2,GAB1,GLS,GPER1,KCNN1,KCNN2,VWA5A,MDM4,NFYA,NUMA1,CDK18,PHKG1,RETREG1,MAPK8,GRAMD1C,RAB3A,KHDRBS2,TMEM206,EMID1,KCNIP1,SCN2B,SEC14L1,SH3BP2,SYBU,PKNOX2,LIMCH1,WDTC1,EMC1,CDK19,ATP10B,PHLDB1,PLCB1,SYT5,POPDC3,GPR161,TGFBR3,R3HDM1,KCNK12,SPHK2,ITM2C,MARCH8,NUP214" Drug 4107_UP Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "DPF1,ADD2,ADGRF5,TRMT9B,AQP4,RGS20,ASPH,SYNJ1,RUNX1T1,CDH10,WHRN,CRY2,MICAL2,SUSD5,NTM,CDON,EFNB3,PLEKHA1,ETV1,DLC1,KIAA1109,FUT9,GAB1,NEU3,GCNT2,GFER,GPR37,GUCY1A2,KLF12,ICA1,ITGA7,KCNJ3,KCNN1,BCO1,NF1,NOVA1,NTRK2,NUMA1,GPR85,PPARA,MAPK7,GDPD2,RAD52,RGS3,SH3BP2,FBXO11,SP4,COLGALT2,PLCB1,KIAA1107,ZMYND8,WIPF1,LAT2,SLC30A4,TIGD6,JPH3" Drug 2232_DN Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "MRTFA,APBA2,APC,ASPH,SYNJ2,MTMR3,CACNA1I,CACNA1A,CDH10,MAGI1,RCBTB2,FOXN3,ARHGEF6,CSF1R,PDE4DIP,SEC14L5,CDON,SLC12A6,EIF4G2,STX2,FAM49B,MPP6,HBS1L,POLL,IL6ST,NF1,NFYA,CDK18,MBOAT7,PRODH,GON4L,PTN,RGS3,TCP11L1,RPS6KA2,KDM4B,DOK5,UNC5B,ARHGAP26,IQSEC2,THSD1,NCDN,VPS13A,PLCB1,ROBO3,TCF7L2,ARHGEF12,TNS2,TRIO,ZMYND8,FAM155A,FLRT2,PLPPR2,ZNF74,WNK1,ST7" Drug 5937_DN LY294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "NDRG2,NME5,SEMA6A,BEGAIN,APC,APP,CDK5R1,SYNJ1,GYG2,CA12,CACNA2D1,TAOK2,COL9A3,C2CD2,CRMP1,FAM169A,SDC3,ARHGEF4,RABGAP1L,KBTBD11,DTNA,RBM12,ACSL4,B4GALNT1,MALT1,GRIK5,MAP4K5,BRINP3,ITPKB,JAK2,KCNF1,KCNN1,BCO1,NPTX1,GRAMD1C,RIPOR1,RET,RGS3,RGS10,FOXRED2,SGK1,SMTN,AJAP1,JMJD6,ARC,ASTN2,ATP11A,KIAA0930,TRIM2,RPGRIP1L,DOCK9,HEY2,VLDLR,XRCC4,SPHK2,RNF146" Drug 7333_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "OSBPL1A,NME5,PLA2G6,CDC42BPA,CFLAR,CAMK2G,USP2,CLGN,ADGRG1,SOCS6,ZFYVE16,GIT2,DMPK,GNE,OPTN,EGFR,IRAK4,ERCC2,EZH1,ATP8A1,KIAA1109,AGAP2,SRCAP,TXNL4A,GLS,TDRKH,LPAR4,HSF2,INPP5B,IPO5,LSS,MAP4,TM6SF1,NF1,CNOT4,NPTX1,PDE4B,PMP22,VPS13C,PTCH1,GTDC1,ROBO1,FBXW7,SBF1,ZNF821,SMTN,SMARCC2,SNCA,ZCCHC24,INKA2,VPS13A,GPR161,TMOD1,HIRA,ZNF142,SLC17A7" Drug 5255_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.49E-06 1.71E-01 7.06E-05 8.03E-04 56 196 "SEMA6A,APBA2,FAM131A,BCL2L2,CLCN4,CRMP1,MICAL2,PDE4DIP,GREB1,DGKG,CTIF,RUSC2,DMPK,EDN3,EGR3,EIF4G2,F5,FGFR1,FOXG1,DPYSL4,ERAP1,ATP8A2,GLS,GRIK5,HLF,ITIH2,JAK2,KCNMA1,KCNN2,LIFR,MID1,MMP16,ADAM22,TAGLN3,MX1,NF1,PCBP3,OMG,TREM2,TMOD2,CDIP1,LRP12,SCN7A,PEX26,PKNOX2,HECW1,PEG10,CDK19,SYT11,ABCC8,EXOC7,DMXL2,SEZ6L,DNALI1,SEMA3B,NAV2" Drug 7285_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.50E-06 1.71E-01 7.08E-05 8.05E-04 51 173 "ADRB2,KIDINS220,MTUS1,SHROOM2,ARNTL,ST3GAL5,NRXN3,CLTB,PREPL,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,JAKMIP2,PLPPR4,EFNA3,EPB41L2,F3,TAOK3,TESK2,BAIAP2,FYN,GLS,GUCY1B1,DIPK1A,KIF5C,MAPT,PCDH9,SERPINI1,PIK3CD,RETREG1,PRPH,SYTL2,ENOX1,RGS4,SH3GL3,DOP1A,TNIK,ARHGAP26,THSD1,RGL1,SYT11,SYT1,KIAA0930,RUNDC3B,SSBP2,DNAJC12,TRIM9,KCNAB1,PLSCR4" Drug ctd:D009538 Nicotine CTD 3.61E-06 1.77E-01 7.30E-05 8.30E-04 211 1005 "ACHE,ARID1A,TMCC3,ADCYAP1R1,GRAMD1B,ADORA2A,ADRB2,TAOK1,ALAD,OGT,BCAS1,API5,APP,AQP4,MADD,ARRB1,CDK13,ATM,ARHGEF7,BTK,CACNA1D,CACNA2D1,CALB1,CALM1,PTBP2,NGB,CAMK2A,SPAG9,RUNX1T1,CBLN1,CCK,SEPT7,CDC42,LRRFIP1,ADGRG1,CHGA,CHGB,CHRNA4,CHRNB2,KMT2C,NRXN3,PLAA,CLCN3,ABCG2,QKI,CNR1,PICK1,CNTN1,AATK,FEZ1,VCAN,CST3,CMTM5,PNPLA8,GPRASP1,HP1BP3,MED24,AK5,DLG4,DRD1,DNM1L,GOLT1B,E2F5,ST8SIA3,EDN1,EDNRA,EDNRB,EFNA2,EFNB3,EGFR,EGR3,EIF5,TNK2,CALCRL,MRPL10,NRN1,F3,TUBB4A,HPCAL4,UFM1,ZNF605,CGREF1,ADGRA1,FYN,GAB1,GABRG2,GAD1,ARPP21,GAP43,GCNT2,GDF1,GFAP,CSDC2,LPAR4,EML4,PLCD4,GRIK2,NR3C1,GRM5,FAM107A,HBA1,SYNPO,HMGCR,HPCA,OPALIN,HSD17B1,HSP90AA1,HTR2A,IRF8,SOWAHA,IGF1,IGSF1,IL12A,ITGAV,ITPKB,JAK2,KCND3,KCNH2,KCNK1,LIG4,SMAD1,SMAD9,MBP,SYT9,LDLRAD3,MEF2C,MT3,MYO9A,FXYD7,NCAM1,NDUFA5,NEFM,NPY,NTRK2,GPR88,OPRL1,PENK,FXYD1,SH3KBP1,PPM1B,PRKCB,PKN2,PRKCZ,MAPK3,MAPK8,MAPK9,PROX1,SNRK,PTAFR,PTX3,PPP2R3C,SLC25A48,RBBP6,RLBP1,S100B,SMPD3,SFPQ,RASA3,SGK1,ZFP30,NTNG1,CLSTN1,RPH3A,SLC6A7,CCDC88A,EFHD1,SNCA,KIF21B,SPP1,UNC5B,NPAS3,SST,SEPT8,PHLDB1,JMJD6,PRRC2C,ARC,SLC37A2,SYT4,TACR1,DDHD2,PDLIM2,ACSL6,ZEB1,SYNE1,SIRT1,HEY1,TIMP4,TJP1,CBX5,KAT6B,NPL,METTL3,ZMYND8,PRR18,UBC,UBE3A,UCHL1,FLRT2,MTCH1,CCDC136,RBFOX3,SLC47A2,ZIC1,SCG2,TMEM163,SLC17A6,ZNF37BP,HNRNPA3,GJC2,CERS6" Drug CID000005428 AC1L1KC5 Stitch 3.62E-06 1.77E-01 7.31E-05 8.32E-04 125 541 "ADCYAP1R1,ADORA1,ADORA2A,ADORA3,AGT,PLA2G6,PHF12,APAF1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BID,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,CAMK2D,CANX,CAST,CCK,KRIT1,RGN,CD38,LRBA,CACNA2D2,CHRM1,CHRNA4,CHRNB2,CLU,CNR1,CREM,CS,CALY,SPOCK2,SACS,RCAN1,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,ERBB4,CACNG3,CACNG2,PTK2B,ACTL6B,SCARA3,FOXM1,FOXO3,CAMKK2,ATP2C1,AHCYL1,KCNMB4,PRLHR,RAPGEF4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,HPSE2,HPCA,MYLK2,IGF1,ITGAM,ITPKB,KCNMA1,KCNN1,MAG,NOS1,NPPA,P2RX7,P2RY1,PDCD2,GPR85,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,FXYD1,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,RIT2,RYR1,RYR3,MAPK12,SLC8A2,SLC8A1,SIRT2,PLCB1,TAC1,TPCN2,ACTR6,CABIN1,TRH,TRPC1,TRPC3,TRPM2,PLD4,CAMK1G" Drug 1022_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.65E-06 1.79E-01 7.37E-05 8.39E-04 54 187 "ARID1A,AMT,KCNAB2,CDK13,ALDH7A1,ST3GAL5,SCAPER,CA4,CAMK2G,SCARB1,LETMD1,SLC4A8,ABCG1,LRIG1,DZIP3,NOS1AP,SNX29,HIPK3,SIDT2,OPTN,ING4,MFSD10,ZNF589,SCARA3,GPR153,B4GALNT1,SESN1,STON1,GPER1,CNTRL,ATXN2L,TJAP1,VWA5A,ADAM22,ZNF862,SLC25A23,MAPK7,CNNM2,RALGDS,FAM184A,BSDC1,RGS10,ZNF821,PPP1R9A,SLC15A2,LIMCH1,CDK19,VAMP1,ARHGEF9,DMXL2,ZNF34,TRIO,TRPC1,MARCH8" Drug CID000003380 flunitrazepam Stitch 3.67E-06 1.80E-01 7.40E-05 8.42E-04 24 59 "ARSE,CBR1,CHRM1,TOX,DBI,GPHN,CACNG2,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,PDCD2,PDE3A,PDE3B,CASC3,SLC6A1,ZEB1" Drug CID000026721 etorphine Stitch 3.67E-06 1.80E-01 7.40E-05 8.42E-04 24 59 "ADCY2,ADCY5,ADCY6,ADCY8,ARRB1,ARRB2,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,RUNX1T1,KRIT1,CLTC,DNM1,DNM2,DNM1L,EPHB1,MCHR1,OPCML,OPRL1,PDYN,PENK,SSTR1,SSTR2" Drug CID003025961 MPEP Stitch 3.67E-06 1.80E-01 7.40E-05 8.42E-04 24 59 "ADORA2A,EEF1A2,PPP1R1B,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,PENK,ENOX1,TPM3,SLC17A7" Drug CID000000723 2-butenedioate Stitch 3.70E-06 1.81E-01 7.46E-05 8.49E-04 64 234 "ACHE,BRAP,ASPA,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BBS2,NFS1,KYAT1,PNKD,CS,CYBB,ARHGAP32,DCT,SNAP91,DRD1,F8,FOXG1,AFF2,FOLH1,COQ5,ATP2C1,GGT7,GGT5,GLS,KCNMB4,GPT2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CLASRP,HRH3,HNRNPK,HTR2A,IDH3A,IDH3B,NOVA2,OGDH,PC,PDE2A,PKM,RNH1,SARS,ASRGL1,BEX1,ADHFE1,TCEA1,CYB561A3,AMOT,SLC13A3,FXR1" Drug ctd:C005460 uranyl acetate CTD 3.72E-06 1.82E-01 7.50E-05 8.54E-04 69 258 "ACHE,NDRG2,ADAR,SLC44A5,APBB1,APC,APP,BCHE,NAE1,CAMK2D,CANX,CBS,CBFA2T2,CHRM1,CHRNB2,MFSD4A,SDC3,APPL1,CTH,PUM1,TOMM20,SNAP91,CHRDL1,PDCD6IP,DTNA,VPS13B,SRRM1,SEC24B,EVL,NSG2,IQGAP2,GLUL,KDM2B,STMN2,HMGB1,SMAP1,LAMP2,STMN1,NCOA7,NAP1L1,NFE2L2,PDE1A,PFKFB4,PIK3R1,C11orf49,CRLS1,PTK2,PLEKHB2,RDX,RPL15,BAALC,RMI1,SCN2B,SCP2,COA1,KDM4B,KIF1B,ABCC8,DNAJC9,KAZN,TNFRSF1B,NEIL2,VSNL1,NDRG4,REEP1,DPYSL5,CSDE1,EVI5,TUBA1A" Drug CID000656673 chromomycin A3 Stitch 3.73E-06 1.83E-01 7.52E-05 8.56E-04 35 103 "APAF1,DYNLL1,BLM,CACNA1A,CACNA1B,CHM,AHCTF1,CX3CR1,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,AHDC1,GFAP,PPARGC1A,TCERG1,PACSIN2,HSP90AA1,IGF1,OGG1,PAH,ABCB1,PACSIN1,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,CNTN2,ZEB1,UBTF,PRTFDC1,JPH3" Drug CID000060703 eliprodil Stitch 3.76E-06 1.84E-01 7.58E-05 8.62E-04 16 31 "GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KITLG" Drug CID000010889 cetyl palmitate Stitch 3.80E-06 1.86E-01 7.65E-05 8.71E-04 12 19 "ABHD6,BLM,CBS,CHGA,CHGB,GAL3ST1,ENO2,KIT,SCG3,NPY,SCG5,SCG2" Drug CID000001257 LY 171555 Stitch 3.84E-06 1.88E-01 7.74E-05 8.80E-04 44 142 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,CCK,LRBA,CHRM1,CNR1,HDAC4,DRD1,RGS17,PTK2B,PPP1R1B,GAD1,GNAO1,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3,CIT,HRH3,HTR2A,KCNJ3,KCNJ5,NPY,NPPA,OPRL1,PDYN,PENK,PRKACB,MAPK3,RGS10,SST,MLST8,ZNF106,TRH,NTSR2" Drug 5216_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "ARID1A,BIN1,SEMA7A,ASPH,SLC4A4,MPDZ,CFLAR,CA4,CALB2,RUNX1T1,SLC16A4,ARHGAP33,NECTIN3,CRY2,CSF1R,ARHGEF4,RIMS2,RIMS3,ARMCX2,RUSC2,EXOG,DRD1,ATN1,DTNA,DNAJB6,TNK2,C3orf18,GAP43,SRCAP,GLYR1,STON1,NR3C1,GUCY1A2,ICA1,IL6R,KCND3,KCNN2,MAP4,NAP1L2,NELL2,NF1,NTRK2,SERPINE2,MTRF1L,KLK6,SAMD9,ZNF493,TCP11L1,HSPA4L,DOCK10,PLCB1,OBSL1,FLRT2,NUP214,FXR1" Drug 3392_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "ACTN1,ADCY2,ADORA1,ADORA2A,ADRA1D,PLA2G6,BEGAIN,AMPD3,MARK4,RASL11B,CADM3,N4BP2L1,CFAP410,CAMK2G,CAST,RUNX1T1,CDO1,TPP1,CSF1R,ARHGEF10,SEC14L5,RASSF2,TMCC2,DLG4,EGR3,TNK2,ERCC2,PIPOX,DCTN2,GRM1,GSTM5,ADAM22,MYO7A,NTRK2,TREM2,CCDC40,SALL1,SFPQ,SNCA,KDM4C,ATP10B,AJAP1,FAM168A,ACSBG1,SYN2,KAZN,SZT2,CRTC1,TEX15,HEY2,TRPM2,WNK1,SEMA3B,KCNAB1,JPH3" Drug 7070_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "MTUS1,BIN1,PPFIA1,APP,CDK13,ASPH,CFLAR,CDK5R1,RAB29,CFAP410,CA12,LHX2,BAG4,PDE4DIP,DZIP3,EDRF1,GIT2,KLHL3,ACOT8,LPAR6,EFCAB2,ERAP1,GPER1,GRB10,DIDO1,IFI16,KIF5C,SCAMP5,TAGLN3,SLC11A2,SETD4,PDGFRA,RC3H2,MED1,PPP2R5C,PRKAR1B,TCP11L1,DOCK10,FBXO11,SNCA,SON,BEX1,CAMTA2,JMJD6,KAZN,DNMBP,SMG6,TCF4,SZT2,PSD3,ARHGEF12,CABIN1,ZMYND8,ZBTB14,WNK1" Drug 3929_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "NME5,ALCAM,LTBP4,APBA2,CDC14B,MARK4,SCAPER,CACNA1A,ARHGEF2,FOXN3,CNTFR,AKAP7,SH2B1,RIMS2,PPP6R2,TMCC2,CDON,ATN1,DTNA,HIPK3,FCF1,EFNB3,FGFR3,DLL3,SRCAP,TDRKH,ADAMTS13,KCNJ5,KCNN1,IPO5,NF1,CNOT4,NTRK2,SERPINI1,FAM120C,RAB3IL1,ROM1,TCP11L1,SEMA6D,SMTN,FAM214B,COA1,SNCA,KDM4B,ZCCHC24,PEG10,SYN2,DMXL2,AP4E1,CABIN1,HIRA,SPHK2,SLC17A7,MPPE1,PHTF2" Drug 1153_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "ABHD6,ADD3,APAF1,APBB2,ARNTL,PDE8B,NCOA1,ST3GAL5,KYAT1,INA,LHX2,DNAJB5,CREM,DOCK4,ZFYVE16,DNAJC6,EFNA3,FAM13A,ENO2,EPS8,ETV1,EXTL2,F5,PCYOX1,ADAM28,GRIN1,SLC2A6,PADI2,MEF2C,ZNF862,NEK1,NRGN,SERPINE2,SERPINI1,RETREG1,PMP22,MINDY2,PPP5C,SIDT1,RPS6KA2,PAQR6,WLS,ITSN1,ANKRD6,ZCCHC24,ZC4H2,RGL1,STXBP1,PJA1,CAMSAP2,TNNT1,RBFOX2,TPM3,SSBP2,TRIM9" Drug 4487_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "APBB1,SYNJ1,IL33,BTRC,KRIT1,SCARB1,FOXN3,CHN2,PLEKHB1,B4GALT6,LHX2,CRY2,DZIP3,DBT,KIAA0753,TMCC2,EDIL3,FAM13A,LPAR6,ETV1,RRAGB,GNAS,GPER1,GUCY1B1,KIF5C,NASP,NDP,NF1,PBX1,PDGFRA,SLC25A23,PTHLH,PTN,PTPRN2,QDPR,SEC61A2,GSTCD,KIRREL1,FBXW7,LGR4,ASAP3,FBXO11,PPP4R3A,TMCC1,WDTC1,TNIK,CAND2,BEX1,CAMTA2,IQCE,DICER1,TMPO,HIRA,NDRG4,FZD3" Drug 2219_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.89E-06 1.91E-01 7.82E-05 8.89E-04 55 192 "MRTFA,SEMA7A,BRINP2,ADGRB2,CFLAR,CFAP410,CAMK2B,ASIC3,SULT4A1,RCHY1,CPS1,GREB1,ARHGAP24,RASSF2,DGKG,DAPK1,HP1BP3,EDNRA,HIPK3,MBNL2,PLXNC1,TNK2,VPS13B,STX2,KIAA1109,FHL1,OGA,RND1,MSL3,GPM6B,RASSF8,KLF12,IL6ST,SMAD1,MYL3,ENPP2,PLCD1,PTAFR,RAD52,ZMAT4,RFX2,KCNIP1,SCN8A,SELL,TRA2B,PPP1R9A,ST6GAL1,ZBTB43,SZT2,KAT6B,ZMYND8,TTPA,VSNL1,SLC13A3,NT5M" Drug CID000003122 AP-7 Stitch 3.95E-06 1.94E-01 7.93E-05 9.02E-04 25 63 "DLGAP1,SNAP91,STX2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,PORCN" Drug 6910_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.06E-06 1.99E-01 8.10E-05 9.22E-04 53 183 "NME5,MARK4,BMP7,BAIAP3,CDH18,WHRN,COL4A5,PREPL,PDE4DIP,ARMCX2,DNAJC6,GNE,OPTN,EPB41L2,STX2,BAIAP2,DPYSL4,NBEA,SORBS1,FYN,CYP46A1,GLS,RAB40B,STON1,KIF3A,KIF5C,MXI1,NEK1,PDE4A,SERPINI1,PIK3CD,PKIA,PRPH,SH3BGR,SH3GL3,WDR47,ZCCHC24,SPTAN1,ELOVL4,TTBK2,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,HEY1,BEX4,NPL,RUNDC3B,SSBP2,DNAJC12,SLC17A7,ITM2C" Drug CID000004362 N-ethylmaleimide Stitch 4.13E-06 2.02E-01 8.10E-05 9.22E-04 119 511 "SYN3,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,AP2A1,MYH7B,MAGEE2,GPAM,SPTBN4,STX16,ATP2A2,ATP2B1,ATP2B2,ATP2B3,KIF1A,CALM1,SYT6,RGN,CD38,ENTPD2,CHRM1,MYL6B,CLTC,BLOC1S6,DNM1,SLC12A6,DTNA,DTNB,EGFR,ELN,SLC43A2,STX2,ERBB4,ACTL6B,POLK,VTI1B,SYNCRIP,ATP2C1,GAD1,GAD2,DISC1,GART,CPLX2,GHR,GLS,GLUL,GOLGB1,GRIA1,GRIA2,GRIA4,KIF3A,GSTM5,GSTT2,HTR2A,IDH3A,IDH3B,KCNB1,KCNMA1,KIF2A,KIF5A,KIFC3,SYTL4,MAT2A,AFDN,STK32C,MT3,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NBL1,OPRL1,CNTN3,PDE4B,ABCB1,POLG,RAB3A,REV3L,FIGN,KIF7,MYH14,STX1B,KIF27,KIF21A,KIF16B,MYO18A,FNDC3A,RPH3A,SLC12A4,NAPB,SNAP25,KIF13A,SPTAN1,KIF1B,STX1A,STXBP1,NSFL1C,MLC1,VAMP1,SYN1,SYN2,SYP,SYT1,SYT5,SMG6,TF,AKTIP,ACTR6,STXBP4,GORASP1,SLC13A3,WNK1" Drug 4545_UP Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RBM10,AP2A2,PLA2G6,APAF1,GAS7,APP,SLC4A4,ALDH7A1,ADGRB2,CACNA1G,SEPT7,EPS15L1,STOML1,C2CD2L,CDON,DTNB,SGK2,APH1A,IRAK4,SCML2,FGF1,DPYSL4,CSPG5,FYB1,DKK3,RND1,GNAL,PRRC2B,RAPGEF4,CACFD1,GRM7,HRH3,ATXN2L,KCNJ5,KCNMA1,VWA5A,MGAT3,MOBP,NCAM2,NF1,NNAT,PDGFRA,PHKG1,PRKCB,CNNM2,PTPRN2,CCDC102B,KCNIP1,SH3BP2,IZUMO4,EMC1,SYNE2,SYN2,ADGRL3,ZKSCAN5,NT5M" Drug 2151_UP Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "C1QTNF1,ALAD,AMPH,ANK1,APAF1,APBB2,APOC1,CADM3,THSD7A,MAP7,REPS2,MAGI1,CLCN4,EDRF1,DLG3,EDIL3,EEF1A2,HEYL,OPTN,SORBS3,EPHB1,ERBB2,CAMSAP1,FHL1,FOXG1,FOLR2,NBEA,GPR153,GAB1,GALC,GPM6B,GRIA4,PADI2,ICA1,KIT,MAP4,AFDN,ZNF862,NRCAM,NTRK2,OMG,PDE1C,PDE4D,RIPOR1,TMEM206,SLC1A7,SLC9A5,PALLD,SPTAN1,TCF7L2,RPGRIP1L,CRTC1,KCTD2,TPD52,FAM155A,SENP7" Drug 3192_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "SEMA6A,ALK,APBA2,CCDC181,ATP2B3,NRP2,HAP1,RUNX1T1,CCKBR,ARHGAP33,TAOK2,NMT2,COL9A3,NCOR2,CSF1,HDAC4,PHYHIP,DMPK,RASGRP2,MTSS1L,EPHB1,ZNF589,FGF1,DLL3,HBS1L,SIGLEC8,GLS,GPD1,PRUNE2,TDRKH,ITPKA,SMAD1,MEF2C,ADAM22,ZNF862,MYT1,PCSK2,LRRN3,GAL3ST4,RERGL,RAVER2,RPS6KA2,SCG5,RPH3A,TROVE2,INKA2,EXOC7,RPGRIP1L,TGFBR3,THRA,PIK3R5,ZNF45,SLC26A10,ITM2C,CAMK1G,NLRP3" Drug 7354_UP Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "PLA2G6,TRMT9B,APLP1,CDK13,SCAPER,CA4,THSD7A,SOCS6,NCOR2,NOS1AP,MFAP3L,RABGAP1L,DSCAM,EIF5,VPS13B,RASGRP2,CDKL3,ST3GAL6,SIGLEC8,POLL,LPAR4,CNTRL,GRIK5,GRM8,ATXN2L,ELOVL5,IL6ST,KCNMA1,KCNN1,MID1,MYT1,NF1,NOS1,NOVA2,NPTX1,PDE4B,MTRF1L,SEPT4,SAMD9,CEP97,RALGDS,KHDRBS2,ZDHHC14,RGS12,RBM34,ZHX3,SPTAN1,TROVE2,ST5,TTBK2,ROBO3,RUNDC3B,WIPF1,KCNK12,XRCC4,WIPF2" Drug 6490_UP Iodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "APBB2,GAS7,RGS20,MARK4,N4BP2L1,ADAM15,FGF17,HAP1,CAMK2G,COL9A3,CREB5,KBTBD11,DMPK,EFNA3,EFNB3,APC2,CEND1,FGFR1,PRELID3A,SRCAP,GFAP,GLI2,SOX21,HAS2,PTGDR2,DHX35,C2orf72,KCND3,MEF2C,MYH7,NELL2,PLTP,PDZRN4,PPP5C,SAMD9,RAB3A,RAD52,RASGRF1,GSTCD,ASAP3,PREX2,FAM214B,PKNOX2,SLC6A9,COA1,SEMA4A,SZT2,PSD3,ZNF34,SLC44A1,CABIN1,ZKSCAN5,VGF,WIPF1,CLIP2,SLC30A3" Drug 460_DN deferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RBM10,NDRG2,AP1B1,APBA2,ARHGAP5,CAMK2G,TBRG4,TJP2,SLC4A7,CHD1L,CREM,SACS,SUGP2,ETV1,DLC1,FAM49B,TRAF3IP2,ZNF274,ARFIP1,DBF4,SMAD1,MBD1,MBNL1,CNOT4,NPTX1,SLC11A2,PCDH9,GPSM2,VPS13C,PTAFR,QDPR,SH3TC2,REV3L,ROBO1,ZC3H14,SUPT20H,R3HDM2,ELMO2,PALLD,SON,FNBP1,ERBIN,CEP68,IQCE,TBL1X,TCF4,ZEB1,TRIM2,WASHC4,TMPO,WIPF1,NSD2,ZBTB38,RNF103,SLC17A7,FIP1L1" Drug 2070_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "BIN1,CDC42BPA,PPFIA3,APP,BCL2L2,SCAPER,CLCN3,NIPBL,VCAN,CTH,ARHGAP32,SNPH,SIRPA,RUSC2,TRAPPC9,E2F5,SIDT2,EPB41L1,TRMO,DENND2A,GNAS,DIDO1,RNFT2,SLC2A6,IPO5,MAP4,NFYA,SLC11A2,PBX1,CCSER2,LRP12,FA2H,MINDY2,MAPK7,BCAS3,GTDC1,HSPA4L,SLC1A3,FAM214B,ZKSCAN3,CDK5RAP2,IFT122,LIMCH1,MAPK8IP3,SEPT8,TTBK2,FBXW11,TCF7L2,TRIM2,FRYL,AHCYL2,HIRA,FAM155A,LMF1,XRCC4,RNF170" Drug 3012_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "SYN3,GRAMD1B,SPARCL1,CDC42BPA,SLC2A11,BMP7,MAP7,CDH10,AKAP6,COL9A2,SLC4A8,CRYBB1,NCOR2,CTNND1,DCC,SPOCK3,DLG4,EXOG,TRAPPC9,ST8SIA3,EGFR,EIF1,EPB41L1,APC2,ARMCX1,DLL3,CHL1,INPP5K,GLI2,SPACA9,HTR5A,KHK,SMAD1,MAP2,MMP16,MX1,NPPA,NTRK3,PCDHGC3,BEND5,GAL3ST4,KCNIP2,SH3BGR,CNKSR2,ST8SIA1,CDK19,TACR1,TAL1,TCF7L2,DNAH7,CHST8,TPM2,TRPS1,SSBP2,VSNL1,SLC17A7" Drug 2248_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADRA1D,MRTFA,APAF1,ADGRB2,SYNJ1,CA12,CAMK2B,CD86,ASIC3,FAM149A,RASSF2,RUSC2,DMPK,SNX29,EFNB3,EPHB1,SPEG,APC2,KIAA1109,AGAP2,GABRA5,GAD1,RND1,MSL3,GNAO1,GNG3,KLF12,MAP4,MATN3,KITLG,MOBP,BCO1,TAGLN3,ZNF862,NELL2,NNAT,PLCD1,LRP12,FAM120C,RAD52,RGS4,ZFHX4,TMEM206,PPP1R9A,SH3GL3,ASAP3,ST6GAL1,BCAN,SLN,POPDC3,TPM2,VAV2,KCNK12,SLC17A7,KCNAB1,PARP11" Drug 407_UP sodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,RBM10,NDRG2,DOC2A,APBB2,ASPH,CADM3,ATP6V0A1,MTMR3,GYG2,RAB29,SYNGR3,LHX2,DNAJB5,LY86,CNTFR,AATK,MFAP3L,DPP6,SIDT2,EFNA3,SRPK3,PLEKHO1,ARMCX1,FGFR1,SEMA4D,GABRA4,HBS1L,NCKAP1,GPR37,NR3C1,NELL2,NRGN,SNX10,PLCD1,VPS13C,LRRC49,C1orf109,TCP11L1,ZCCHC24,DBNDD2,CLASP2,MAPK8IP3,PRRC2C,ANKRD28,CRTC1,SIRT1,TMEM121,BEX4,TRIO,TRPC1,ZNF45,REEP1,MAP3K12,GDPD5,AAAS" Drug 7142_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "APP,LGR5,ALDH7A1,KIF1A,BID,CFLAR,BTRC,CFAP410,PTBP2,SCARB1,CHRNA4,RAB28,DNAJB5,WHRN,HINFP,CSNK1E,SLITRK5,EDRF1,DLG3,EGFR,KAT8,BAIAP2,SEMA4D,TRMO,GAD1,ZMYND11,TMEM8B,ZNF276,CRCP,RNFT2,ACOT7,SCIN,INPP5B,KIF5C,NDUFA5,NUMA1,MAPK7,PROX1,PTPRN2,RAD52,SEC61A2,ZNF671,SH3BGR,FUZ,OGDHL,EMC1,CEP68,EXOC7,TCF4,TRPC1,NSD2,TRIM9,WNK1,EVI5,VPS35L,MPPE1" Drug 4135_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,NME5,AK2,APBB2,EPB41L5,PDE8B,MARK4,BRINP2,ATM,CFLAR,SYNJ2,CACNA1I,B4GALT6,STOML1,CSF1R,FAM169A,GREB1,TBC1D5,RIMS3,GIT2,DTNA,SGK2,EFNA3,ING4,FGFR1,FAM49B,GAD1,GLYR1,IL6ST,KCND3,IPO5,MAP4,NF1,NOS1,PDE3B,PLCD1,PPP2R5C,MAPK7,MAPK8,PLPPR1,PTHLH,ZDHHC14,CPEB3,COA1,ZHX3,ZBTB43,TROVE2,CLSTN2,MAPK8IP3,POPDC3,KIAA0930,AP4E1,KCTD2,ZMYND8,ZKSCAN5,PHTF2" Drug 2164_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "NDRG2,FAM131A,SLC4A4,SLC16A4,CDC27,CLGN,SOCS6,CREM,CRY2,RNF14,SIPA1L1,C2CD2L,DTNA,SGK2,MBNL2,C3orf18,EIF1,PRELID3A,GALC,ALDH1L1,ADAM28,GNAO1,GRIK5,MAP4,MBNL1,ZNF862,NFYA,CNOT4,NUCB1,NUMA1,PLCL1,PURG,LRP12,POLR2F,PTPA,MAPK10,PTPRN2,RAD52,BSDC1,EMID1,AMBRA1,BTBD3,HECW1,NPAS3,LHPP,ST5,FAM168A,PLCB1,EXOC7,CAMSAP2,R3HDM1,RBFOX2,CDK20,FLRT1,CLIP2,KLC2" Drug 2435_DN Bisacodyl [603-50-9]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "APOC1,APP,MARK4,SLC4A4,LDLRAD4,CBFA2T2,SCARB1,FOXN3,ARMC8,CRY2,CSNK1E,PPP6R2,TBC1D5,MAML1,DBT,KIAA0753,SGSM2,RCAN1,DTNA,ABI2,COQ7,RASGRP2,CD320,TRMO,GABRA2,SPIN1,LILRA2,EML4,VSIG4,LSS,CNOT4,NUCB1,NUMA1,PIK3CD,POLG,CNTLN,PTAFR,PTK2,EMID1,SEC14L1,RASA3,SCG5,SH3BP2,DOCK10,ZKSCAN3,IZUMO4,TROVE2,PDLIM2,TCF7,TK2,KCTD2,SSBP2,WNK1,MAP3K12,GDPD5,ACTR3B" Drug 6649_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ACHE,ADRA1D,BEGAIN,AMPH,APAF1,APBB2,DDX3Y,BAIAP3,BRSK2,RUNX1T1,ADGRG1,IFFO1,CPS1,ARHGEF4,TOX,RIMS3,BRINP1,DCC,SRGAP3,HS3ST2,DYRK1A,NCALD,IGSF6,ST3GAL6,ERGIC3,OGA,GABRA2,LYVE1,TPPP,IRAK3,KCND3,KCNJ5,MEF2C,MGAT3,ADAM22,MYH7,NOVA2,NRCAM,PBX1,PDGFRA,PENK,RETREG1,GDPD2,ELOVL2,PTN,RYR1,RASA3,NTNG1,SLC6A9,ZNF334,RIMS1,KIF13A,MYT1L,SEZ6L,TPM1,SLC26A10" Drug 3723_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,APP,CDK13,ALDH7A1,MYRF,CANX,RCBTB2,PLAA,CLCN4,CLU,QKI,CPS1,HAPLN1,NCOR2,MICAL2,CTNND2,TOX,DAPK3,SMG7,DTNA,SGK2,FCF1,SIDT2,ING4,TUBD1,ETV1,VPS26C,PTK2B,ATP8A1,ERAP1,GLUL,GPM6A,INPP5B,KCNMA1,MDFI,MMP16,CNOT4,PFKFB2,MINDY2,CEP41,PRKAR1B,FAM120C,RAB3IL1,CLIP1,CSRNP3,ZHX3,EMC1,TROVE2,ELOVL4,MLC1,PSD3,TMPO,TRIO,NSD2,REEP1,MVB12B" Drug 6335_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADORA2A,KCNAB2,PPP4R4,MARK4,ALDH4A1,SLC4A4,SYNJ2,BAIAP3,IL33,HIP1R,ARHGAP33,CHRNB2,CLCN4,DNAJB5,CREM,FEZ1,VCAN,RIMS2,ARHGAP24,TBC1D5,RIMS3,SEMA3D,FAM13A,TENM1,IGSF6,ETV1,ZNF589,SEMA4D,GAP43,ADAM28,GFER,GLYR1,LPAR4,INPP5B,TM6SF1,MIA2,NUMA1,PPARA,GAL3ST4,KCNIP1,ZFP30,FRMPD1,SLC1A7,CDK5RAP2,SMARCD3,IFT122,KDM4C,PHLDB1,ZEB1,OBSL1,NSD1,TK2,ICAM5,UBE3B,NUP214,GAN" Drug 6708_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ABAT,ADGRF5,AMPH,APAF1,APBB1,DDO,AQP4,PPP4R4,ARHGDIG,ATP2B3,KSR1,BAIAP3,BTRC,CFAP410,CACNA2D1,CBS,CACNA2D2,NRXN3,CSF1,CTH,RIPOR2,DAPK3,CTIF,MYEF2,MFAP3L,DLC1,ALDH1L1,GPR17,GRK4,GRIK5,SHISAL1,ITPKA,VWA5A,ADAM22,MT1M,MYH3,NCAM1,NRCAM,PFKFB4,CNNM2,PTPRH,CRTAC1,RGS4,RNASEL,RPS6KA2,RPH3A,SLC11A1,INKA2,SYT1,COBL,TNS1,VIPR2,PARP6,STMN4,KCNAB1,GAN" Drug 6686_DN Dichlorphenamide [120-97-8]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,MRTFA,KCNAB2,NRP2,ST3GAL5,CFAP410,KRIT1,FOXN3,TAOK2,CLCN4,PICK1,CPS1,PDE4DIP,ARHGEF4,PARD6A,SGSM2,RABGAP1L,CHRDL1,HSD17B14,COQ7,DENND4A,F8,GAD1,ICA1,SCIN,IL6ST,KIF5C,TM6SF1,OPCML,PDE4B,RETREG1,GRAMD1C,PRPH,CNNM2,PTN,ZSCAN2,RAB3A,SH3TC2,KHDRBS2,ARHGEF10L,MRPS18A,ZNF671,RPS6KA2,SUPT20H,UHRF1BP1L,UNC5B,DDN,NCDN,PLCB1,SZT2,TMEM121,TK2,XRCC4,WNK1,FIP1L1,PCBP4" Drug 5506_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ABR,CDC42BPA,APBA2,DDO,PLA2G4C,ASPH,CNTNAP2,RIMS2,DLG3,SGK2,ELN,ETV1,FER,FUT9,RUNDC3A,ADAMTS13,GRM1,ITIH2,KCND3,KIF5C,IPO5,MAN2A2,MBD1,NEFM,NF1,GPR85,PIK3CD,STRN3,PILRA,LRRN3,PTCH1,ELOVL2,ZNF493,RGS12,NEK11,RPS6KA2,RYR1,CPEB3,SLA,ZKSCAN3,COA1,FAIM2,ZNF415,PEG10,NPAS3,NCDN,VAMP1,CRTC1,SLC35G2,WBP2,ZMYND8,TTPA,LAT2,XRCC4,ZNF24,SCG2" Drug 4245_UP Cefalonium [5575-21-3]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "PKP4,APC,GAS7,BCAS1,SLC2A11,ATP6V0A1,NRP2,MTMR3,CFAP410,HAP1,RUNX1T1,FOXN3,CNTN1,HAPLN1,LRIG1,NTM,CHRDL1,HIPK3,COQ7,EPHA5,KCNMB2,DCTN2,GRIK5,ITIH2,ITPKA,KCNC1,KIT,LMO1,MAP2,LYRM9,NF1,NOS1,PCBP3,DDR2,CLDN11,PDE2A,PDE3B,LRRN3,PTPRB,PTPRN2,PTPRO,ACSS3,ENOX1,NTNG1,SLN,SNCA,TMCC1,ZHX3,ARHGAP26,DMXL2,AP4E1,ZNF34,UCHL1,FLRT2,ZNF225,NLRP3" Drug 2481_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "GRAMD1B,APBB2,ADAM23,BACH1,SCAPER,CANX,CD86,QKI,IQCK,SLC4A7,RCHY1,CTNND1,RIMS3,RUSC2,RABGAP1L,DTNA,FCF1,SIDT2,EFNA3,ST3GAL6,KIAA1109,FHL1,GALC,ARFIP1,LILRA2,EML4,PADI2,MAP4,NCAM1,NF1,NFYA,NUMA1,MINDY2,MAPK7,SAMD9,PTAFR,PTK2,C12orf49,RASA3,FAM102A,NUBPL,PPP4R3A,CCDC88A,SPTAN1,TSPYL2,SS18,NXT2,TCF7,ZEB1,ICAM5,KCTD2,PARD3,PIK3R5,LMF1,LAT2,SENP7" Drug 2780_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "FAM131A,APP,CDK13,NUMB,STX16,GYG2,SOCS6,DNAJB5,QKI,RCHY1,BAG4,NR1D2,HIPK3,MBNL2,SCML2,FER,KIAA1109,FGFR1,PDLIM5,DISC1,INPP5K,RASSF8,HSD17B1,KPNA5,MATK,MDM4,KITLG,MMP16,ZNF862,SETD4,PDE3B,LRP12,RAD51D,ZCWPW1,RGS10,RNASEL,ROBO1,TCP11L1,SH3BGR,SLC6A8,BTBD7,SMARCD3,WDTC1,KDM4C,CDK19,NXT2,INKA2,ATP11A,ANKRD12,KIAA1107,ZNF34,TIAM1,RBFOX2,DNALI1,UBE3B,PHTF2" Drug 6796_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,SLC12A5,LTBP4,CDK10,DNAH17,CFLAR,KSR1,CACNG1,SOCS6,DNAJB5,CLOCK,SIPA1L1,GREB1,ARHGEF4,DAPK3,CTIF,RUSC2,DMPK,DTNA,ST8SIA3,EDN1,IQCG,PDLIM5,CAMKK2,GPER1,GPR37,JAK2,LIG4,VWA5A,MAN2A2,MMP16,MPP2,TAGLN3,NTRK2,OPCML,STRN3,PRKAR1B,SNRK,KCTD17,ZFHX4,MYH14,ASAP3,DOCK10,SMTN,SMARCC2,ZSWIM8,CDK19,TSPYL2,ATP10B,TROVE2,PLCB1,TACC1,MCF2L,PSD3,PLPPR2,ZNF24" Drug 3694_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "GRAMD1B,AMH,ANK1,APC,APP,ASPH,ATP1A3,SLC4A4,N4BP2L1,IL33,BTRC,CFAP410,THSD7A,CBFA2T2,DNAJB5,SULT4A1,RAB26,HAPLN1,CTH,PHYHIP,NTM,ARNT2,FEM1B,EPHA5,GAB1,SIGLEC8,ADAM28,GPM6B,LILRA2,LSS,MOBP,PDE2A,PDGFRA,SMOX,STRN3,TNPO2,SYTL2,PTPRO,RALGDS,RGS4,SUGCT,PAQR6,STUM,DOCK10,SHANK2,ELMO2,CXXC4,MLC1,CRB1,SPX,ZKSCAN5,UCHL1,LAT2,SLC30A4,PRDM2,SEMA3B" Drug 2809_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "PLA2G6,ARHGDIG,CDK13,PTCH2,CFAP410,CAMK2B,CHM,SULT4A1,AKAP6,WHRN,CRMP1,CSNK1E,ARHGEF4,ARMCX2,DYRK1A,EDIL3,MBNL2,EIF4G2,STX2,FCGRT,CAMSAP1,EFCAB2,PDLIM5,FYB1,GAD2,ERAP1,SEPT9,ICA1,ITIH2,KCNN1,VWA5A,AFDN,CNOT4,PCDH9,PDE3B,PLCD1,PLTP,PPP5C,KHDRBS2,MYH14,SYNDIG1,DOCK10,RPH3A,ARHGEF40,PDZD2,SPTB,ST5,DAAM2,CABIN1,FAM155A,UBE3A,PLPPR2,VAV2,SLC30A3,PRDM2,SEMA3B" Drug 5250_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "FAM131A,CDK13,DDX3Y,ATM,CFLAR,CACNA1I,BAIAP3,CAMK2B,CDH18,RCBTB2,SULT4A1,CSF1,SDC3,DCAF4,SEC14L5,SV2B,DYRK1A,EFNB3,EPHB1,EFS,PTK2B,OLFM1,FGFR3,FOXG1,KHDRBS3,OGA,GAD1,HBS1L,GLYR1,POLL,GRM8,ITGA7,KCNC1,KCNK2,MX1,NTRK2,PLCD1,LRP12,MINDY2,RGS12,RASA3,HKDC1,SLC1A7,OGDHL,KIF13A,HECW1,CDK19,TSPYL2,NPAS3,TBL1X,DMXL2,LILRA4,FLRT2,VGF,WIPF1,XRCC4" Drug 5692_UP Josamycin [16846-24-5]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADORA2A,CDK13,MARK4,CADM3,CFAP410,CACNG1,CAMK2B,INA,CHM,CHRNA4,SLIT2,LHX2,EDRF1,MAML1,C2CD2L,SPOCK3,MRNIP,EXTL1,ZNF589,HPCAL4,FOXF2,DCTN2,SORBS1,OGA,GAD1,GAD2,SRCAP,TDRKH,NR3C1,SOX21,TJAP1,MAP4,MDFI,NUMA1,P2RY1,PDE4D,TMOD2,PFKFB2,CDIP1,LRP12,PPP1R1A,ELOVL2,PTN,ENOX1,ZNF821,SH3BP2,PPP1R9A,SLC1A2,SLC11A1,PEG10,PLCB1,TAL1,SYNE1,CRTC1,SEZ6L,MKRN3" Drug 7289_UP Phenindione [83-12-5]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "AGT,ADGRF5,KCNAB2,APOC1,CDK10,ALDH7A1,SYNJ2,MYRF,CACNG1,CDH8,TAOK2,NRXN3,NMT2,HOMER3,AKAP5,ARHGEF10,CHRDL1,HIPK3,EFNA3,EPB41,COQ7,MTSS1L,ZNF44,GAD1,GNAO1,GPR19,SPACA9,DHX35,TJAP1,KHK,MATN3,ZNF862,PALM,PFKFB2,PFKFB4,FA2H,CNNM2,ELOVL2,PEX5,TTLL7,RTN1,SUPT20H,AMBRA1,PPP4R3A,SIRT2,ZHX3,SPP1,UNC5B,SPTB,THSD1,SS18,MAPK8IP3,THRA,LAT2,KCNAB1,DPF3" Drug 1508_UP Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "APBA2,APLP1,MARK4,SLC2A11,CADM3,MPDZ,SYNJ1,SCAPER,KRIT1,SOCS6,CNTFR,SLC4A7,AKAP12,NCOR1,CTNND2,VPS13B,MTSS1L,FHL1,FOXG1,PDLIM5,POLL,NR3C1,TJAP1,IL6ST,JAK2,MEIS2,ADAM22,MSR1,ZNF862,CDK18,RETREG1,TNPO2,PPARA,PPP5C,MAPK7,PRPH,VPS13C,RAB3A,RAB3IL1,CEP97,REV3L,RASA3,SLC22A4,CDK19,SPART,MAPK8IP3,ANKRD12,KIAA1107,DMXL2,CRTC1,KAT6B,CDK20,RUNDC3B,FLRT2,DNALI1,MPPE1" Drug 7464_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,AMPD3,KCNAB2,APC,SEMA4G,ATP1A3,MTMR3,GYG2,CBFA2T2,MAGI1,RCBTB2,CHRM4,ARMC8,ARHGEF10,VCAN,TBC1D5,DAPK3,JAKMIP2,MFAP3L,TMCC2,EDN1,CELSR3,MRNIP,ELN,BAIAP2,AGAP2,GAB1,ERAP1,SYT17,RAB30,RNFT2,ACOT7,ITGA7,KCNB1,KCNC1,KIF5C,SMAD1,MAP4,MAPT,MPP2,NPTX1,SLC25A23,PRKAR1B,PRPH,WDR25,PTN,RIPOR1,PAQR6,IL17RB,SNCA,WDTC1,ASTN2,EXOC7,PARD3,TFIP11,PRDM2" Drug 6453_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADORA1,NR0B1,CCDC181,ATP2B2,CADM3,N4BP2L1,SCAPER,SGCE,CACNA1D,TPP1,QKI,SULT4A1,WHRN,SLC4A7,CSF1,RGS6,RIMS2,SPOCK2,DMPK,HS3ST2,EDNRB,EFNB3,RCAN2,VPS26C,DLC1,HBS1L,SIGLEC8,GFER,GPM6B,ITIH2,KIT,MEF2C,MSI1,GPR85,PLCD1,PLEC,PRKAR1B,FOXRED2,SEMA6D,PKNOX2,SLN,COA1,TSNAXIP1,SOX10,HECW1,SS18,AJAP1,SYN2,SYT5,HIF3A,DICER1,VAV2,WIPF1,CLIP2,EMSY,NT5M" Drug 4507_UP Ampyrone [83-07-8]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "AP2A2,APAF1,PPP4R4,PDXK,ATP2B2,MTMR3,LDLRAD4,CACNA1D,LHX2,RAB33A,ABCG2,HOMER3,CNTN1,WHRN,IFFO1,SEC14L5,CHRDL1,ATN1,CEND1,PDLIM5,B4GALNT1,ERAP1,RND1,ATXN2L,ICA1,TJAP1,ITIH2,CD200,ADAM22,NPY,NOVA2,NPR2,NTRK2,RETREG1,NLE1,PPP5C,MYH14,KCNIP1,RYR1,WDR37,KANSL3,ZNF334,SLCO1A2,KIF21B,ZHX3,ZSWIM8,SPTAN1,ATP10B,PLCB1,MCF2L,SMG6,TPM1,VAV2,VIPR2,ZNF225,GAN" Drug 2810_UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ALCAM,ALK,AMPD3,SEMA7A,APAF1,DNAH17,ATP2B2,CACNA1I,BAIAP3,CD86,ARHGEF1,CBFA2T2,CHRNB2,RAB33A,CNTNAP2,HS3ST2,EDIL3,C3orf18,VPS13B,DMTN,KCNMB2,PIPOX,ZNF589,KIAA1109,CAMSAP1,AFF2,FUT9,GCNT2,MSL3,CNTRL,GSN,KCNN1,KCNQ3,NUCB1,TREM2,PAX6,PLCD1,PRKAR1B,CCDC40,C1orf54,MYH14,RPS6KA2,STUM,CNKSR2,STX1A,VAMP1,DOCK9,CABIN1,TRIO,LAT2,ZIC3,PRDM2,SEMA3B,PLSCR4,KAT6A,SENP7" Drug 7287_DN Trichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "AP2A2,NCOA1,CFLAR,ST3GAL5,HIP1R,BAG4,CSNK1E,PPP6R2,ARHGAP32,SGSM2,DLG3,F8,SCARA3,DPYSL4,DLL3,SRCAP,GFER,GPM6B,MAP4,NASP,NF1,NFYA,SLC11A2,NUMA1,PLCD1,SMIM7,PRKAB2,PTN,RAB3IL1,MCMBP,LGR4,SAFB,MAPK12,SBF1,FAM102A,PEX26,EPN2,KBTBD4,BTBD7,LIMCH1,TMCC1,SPATA7,CDK19,VAMP1,ROBO3,PDLIM2,IQCE,FBXW11,PARD3,ZKSCAN5,HIRA,NSD2,XRCC4,EVI5,FIP1L1,RNF170" Drug 4842_DN Picrotoxinin [17617-45-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,KIDINS220,APBA2,APLP1,PPFIA3,ARRB1,BRINP2,CFLAR,CCNT1,ARHGAP33,MAGI1,CRLF1,CACNA2D2,ARMC8,SLC4A7,CNTNAP2,DTNA,EDNRA,FCF1,SORBS3,ERCC2,ZNF589,FGFR1,GLS,HNMT,INPP5B,IPO5,MAP4,MPP2,CNOT4,OGG1,RETREG1,SLC25A23,TMEM104,PEX5,RAD52,RGS12,SH3BP2,ITSN1,FAM214B,SLC6A8,SLC20A2,INTS9,SNCA,TMCC1,ZCCHC24,CEP68,EXOC7,IQCE,SATB2,TMOD1,TRIO,PLPPR2,KCNAB1,WIPF2,UBE3B" Drug 6745_UP Midecamycin [35457-80-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASPHD1,SEMA6A,BEGAIN,KCNAB2,GAS7,DDO,SLC4A4,CADM3,PROM1,BMPR1B,BAIAP3,CFAP410,CA12,CD86,SYNGR3,NEURL1,CHGA,NDST3,IFFO1,HAPLN1,CHD5,SEC14L5,DAPK3,PLPPR4,SRPK3,LRRC17,NRN1,EFCAB2,RAB30,TOX3,GNG3,GPR17,HTR2A,MT1M,MX1,MYH3,LYRM9,NELL2,NTRK3,NECAB2,PTPRB,NTNG1,SLC2A5,SNCA,KIF13A,ZHX3,SP2,ATP10B,TF,TPM2,CADM1,VAV2,WIPF1,PARP6,SLC17A7,KCNAB1" Drug 2570_UP Methimazole [60-56-0]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "NDRG2,ADORA3,C1QTNF1,BEGAIN,PKP4,APBB2,PPFIA3,PPP4R4,ATP6V0A1,BACH1,BTRC,CFAP410,CAMK2G,MAP7,USP2,CLGN,ZFYVE9,CRY2,VCAN,PDE4DIP,RUBCN,EDRF1,ARHGAP32,EXOG,DTNA,EFNA3,PTK2B,SEC23B,IQCG,TMEM8B,RND1,GLYR1,GSN,KLF12,IL12A,KCNN1,LSS,MAP4,NAP1L2,OXTR,PDE4D,ENPP2,PTPRN2,ZNF821,KDM4B,IZUMO4,RAP1GAP2,VAMP1,ARHGEF9,KIAA1107,PSD3,ARHGEF12,TMOD1,FLRT1,LAT2,PHTF2" Drug 4806_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "SEMA6A,CDC14B,BRINP2,BTRC,CAMK2G,CBFA2T2,ARHGEF2,PLEKHB1,TAOK2,RAB28,FAM149A,NECTIN3,CNTNAP2,RIMS2,DAPK3,MAGI2,EFNA3,ERBB2,DENND4A,CORO2B,CAMSAP1,AGAP2,GALC,HPGDS,POLL,ITIH2,KCNH2,KCNN2,KIF5A,LIG4,MID1,ZNF862,NFYA,SLC25A23,PPP5C,MAPK7,MAPK8,PRPH,TCP11L1,FRMPD1,ASAP3,CPEB3,FNDC3A,FAM214B,WDTC1,SS18,SYT5,EXOC7,TBCEL,R3HDM1,TRIO,FAM155A,WIPF1,CLDND1,ST7,AP3B2" Drug 4730_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,ADORA1,BRINP2,B3GALT2,BAIAP3,CACNA1A,KALRN,RUNX1T1,EPS15L1,MYRIP,NCOR2,ARHGEF10,TMCC2,ATN1,EDN1,HIPK3,HEYL,RBM12,EGR3,RASGRP2,MTSS1L,FYB1,GABRA2,NEU3,GPR162,PCLO,GRIK2,GSN,HLF,ICA1,TJAP1,NPY,EPN1,MTRF1L,MAPK7,PTCH1,PTHLH,C1orf54,RYR1,ASIC4,RASA3,SYBU,KDM4B,UNC5B,SYP,ATP11A,ADGRL3,TCF4,RPGRIP1L,SEZ6L,UGT8,WIPF1,LAT2,SEMA3B,NAV2,HRASLS" Drug 1886_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; PC3; HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "PLA2G6,C1QTNF1,BIN1,AMT,APBB1,KCNAB2,MTMR2,CAMK2B,SOCS6,CHN2,FAM189A2,FAM169A,RUSC2,C2CD2L,SMG7,AK5,DTNA,EFNB3,PLEKHA1,KIAA1109,FGR,C1orf61,TMEM8B,DISC1,C1QL1,CRCP,EML4,GSTM5,GUCY1A1,NXPH3,KCNB1,NPPA,CLDN11,PAK3,CDK14,ZNF426,MAPK7,CNNM2,ARID4A,RPRD1A,MYH14,FAM102A,ANKRD6,ARHGEF40,SLC11A1,KDM4B,COLGALT2,TCF7L2,ZMYND8,LMF1,VSNL1,CLIP2,WNT7A,XRCC4,ZNF24,NUP214" Drug 5403_UP Chlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADD2,LTBP4,MRTFA,ASPH,CACNA1I,BAIAP3,CACNA1D,CDC42,CRYM,SEC14L5,DMPK,EDNRB,EFNB3,SORBS3,COQ7,RASGRP2,PIPOX,RRAGB,PTK2B,FGFR3,FHL1,KHDRBS3,TRAF3IP2,TMEM8B,SRCAP,C1QL1,GLS,STON1,PCLO,ADAMTS13,NR3C1,MAOB,MAP4,MID1,BCO1,NEUROD1,SLCO1C1,PFKFB2,LRP12,POU6F1,CEP41,PTHLH,MYH14,TCP11L1,SMARCD3,LIMCH1,ZHX3,SAMSN1,PLCB1,ARC,DMXL2,KIAA0930,PARD3,TRPM2,PDIA2,SLC30A4" Drug 6385_DN 5707885; Down 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADORA2A,SYT13,SLC4A4,CFAP410,CALB1,SLC16A4,CDH18,CACNA2D2,SLC22A6,WHRN,AATK,ARHGEF10,SDC3,CTIF,C2CD2L,EDNRA,ELN,EPB41L1,IGSF6,SPEG,KIAA1109,FYN,GAB1,SRCAP,GNG3,GRIK5,GRM1,CELF3,ITPKA,KCNMA1,L1CAM,AFDN,MOBP,MYO7A,NF1,PAX6,PDE4B,MTRF1L,POU3F2,RAB3IL1,RAVER2,SATB1,DOCK10,SORCS3,PDZD2,SOX2,INKA2,MAPK8IP3,SYNE1,TRO,WIPF1,LAT2,SLC13A3,SLC30A3,ITM2C,NUP214" Drug 4249_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "DPF1,ACTN2,ADORA2A,SEMA7A,APBB1,GAS7,BMP7,SYNJ2,CALB2,HIP1R,CBLN1,FOXN3,SULT4A1,CNTN1,HAPLN1,CSF1,LRIG1,FEZ1,MFAP3L,MAGI2,DTNA,TNK2,LRRC23,EPHB1,PTK2B,DCTN2,HBS1L,NEU3,PCDH17,IL6ST,ITGA7,ITIH2,KIT,LAMA2,MMP16,NCAM2,NF1,NOS1,NPR2,NUMA1,KCNK10,ACSS3,CCDC40,RET,MYH14,ROM1,KCNIP1,SCN2A,ST6GAL1,ZNF334,SOX15,ZHX3,TACR1,TMOD1,ZNF24,ZNF225" Drug 2222_DN Amidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "KIDINS220,LTBP4,BIN1,KCNAB2,EPB41L5,MARK4,CFLAR,BMP7,MTMR2,ARHGEF2,LHX2,PICK1,SH2B1,CRY2,ARHGEF4,SEC14L5,CDON,RCAN1,EFNA3,ING4,DMTN,LRRC23,ZNF589,CAMSAP1,ANKFY1,FAM49B,PRELID3A,INPP5K,GLYR1,RNFT2,SLC2A6,RASSF8,HNMT,ICA1,IGSF1,KCNN2,LMO2,LSS,MPP2,NAP1L1,NPR2,PTN,ZSCAN32,RIPOR1,RAB3A,ZDHHC14,GSTCD,PEX26,ARFGAP1,EMC1,ROBO3,EXOC7,HPS4,SEMA3B,URM1,UBE3B" Drug 6060_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "NDRG2,KIDINS220,SEMA6A,CDC42BPA,SEMA7A,ARRB1,ALDH4A1,CFLAR,CACNA1I,LDLRAD4,CFAP410,CACNA1D,CHRNB2,CNTFR,CRY2,ATRNL1,VCAN,GREB1,ARMCX2,ZNF804A,MAGI2,LYPD1,DNM2,HIPK3,EFNA3,MBNL2,FER,FHL1,FOXG1,IQCG,PDLIM5,RND1,GLYR1,POLL,FERMT2,KCNH2,KCNN2,KPNA5,MIA2,KITLG,NLE1,PPP5C,PRKAB2,GON4L,PEX5,RAD52,RNASEL,WLS,SEMA6D,SH3BP2,ASAP3,SLC1A7,ELOVL4,PHLDB1,PLCB1,EXOC7" Drug 3088_UP Idazoxan hydrochloride [79944-56-2]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "SYN3,ACTN2,AMPH,ANK3,PKP4,CDC14B,CCDC181,MPDZ,BMP7,CCK,CHRNA4,TAOK2,LHX2,CNN3,AKAP7,CREM,DZIP3,EDRF1,SNPH,SPOCK2,SMG7,DLG4,DMPK,DNM2,EDNRA,SIDT2,ING4,TNK2,EPB41,LRRC17,RASGRP2,BAIAP2,GPR153,ALDH1L1,FAM107A,MAPT,AFDN,TAGLN3,P2RY1,GPR85,NECAB2,PPARA,PPP2R2B,CEP41,PTPRN2,KDM4B,WDTC1,IZUMO4,MTCL1,TBCEL,IQCE,ACSL6,TNS1,TUBB1,STMN4,NLRP3" Drug 2515_UP Hexestrol [84-16-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "AGT,NR0B1,ALK,LGR5,SEMA4G,PRX,PROM1,KALRN,CAMK2B,CLGN,CLCN4,CNTFR,FAM149A,COL9A3,CREM,CTNND1,KIAA0513,EXOG,TNK2,CEND1,AFF2,GAB1,GATM,GLS,GNAL,GNG4,RAPGEF1,KIF3A,KCNJ5,L1CAM,CD200,MPP2,MTRF1L,PMP2,PPARA,DCHS2,CNTLN,RNASE1,ZFHX4,EMID1,CNKSR2,ABLIM3,SMTN,LIMS2,PEG10,CLSTN2,MAPK8IP3,PHLDB1,ASTN2,TBCEL,WSCD1,VAV2,BEST1,VSNL1,SEMA3B,KCNAB1" Drug 2554_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ABHD6,AMT,PPFIA4,APBB2,CDK5R1,SCAPER,SCARB1,ARHGAP33,AKAP7,SEC31B,SIPA1L1,ZNF337,SV2A,CDON,DNM2,EEF1A2,CELSR3,LPAR6,LRRC23,ST3GAL6,OGA,ERAP1,SRCAP,GNG3,LILRA2,SPACA9,NCKAP1L,LSS,MIA2,OGG1,CCSER2,PLEC,PLTP,PTCH1,RAB3IL1,CEP97,SBF1,SIRT2,ZKSCAN3,ZNF667,MYH15,IZUMO4,SPTAN1,RBM26,MAPK8IP3,STX1A,TCF7,TCF7L2,CHST8,R3HDM1,TNNT1,TPM1,ZMYND8,LMF1,MAP3K12,EVI5" Drug 3622_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,AP2A2,LTBP4,BEGAIN,APBB2,CFLAR,LDLRAD4,ARHGEF1,SLIT2,STOML1,PDE4DIP,SEC14L5,DMPK,DTNA,CEND1,ZNF589,KIAA1109,GAB1,ALDH1L1,COPS8,MSL3,GPM6B,GSN,MAOB,MAP4,MMP17,NPTX2,NUMA1,SERPINI1,EPN1,PRKAR1B,MAPK8,RELN,GON4L,PTN,ZSCAN2,FAT4,MYH14,KCNIP1,SH3BP2,SLC2A5,BTBD7,SNCA,TNIK,ARHGAP26,SPTAN1,INKA2,RGL1,ATP11A,EXOC7,TBCEL,DOCK9,PLPPR2,WIPF1,MAP3K12,SSPN" Drug 3011_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,ARID1A,ADCY2,FAM135A,AMPH,CDC42BPA,SEMA4G,CCDC181,PROM1,BMP7,HAP1,USP2,CDO1,CHN2,JAM2,ZFYVE9,SULT4A1,COL9A2,CPS1,PDE4DIP,CTNND2,MAGI2,EXOG,SGK2,SRPK3,DCTN2,GABRA2,GAD2,ERAP1,RUNDC3A,STON1,SPACA9,SYNPO,SCIN,IL6ST,JAK2,KCNQ3,SCAMP5,AFDN,MPP2,NUMA1,OXTR,PDE4A,FSD1,BEND5,SEMA6D,LIMS2,SLN,TNIK,ZC3H13,CDK19,ATP10B,TPM3,SSBP2,ZNF225,PMEPA1" Drug 6756_UP Lynestrenol [52-76-6]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ACTN2,KIDINS220,PLA2G6,KCNAB2,AQP4,CDK10,SLC4A4,CACNG1,HAP1,SLC16A4,FOXN3,VAX2,VCAN,MFAP3L,C2CD2L,SMG7,TENM1,F5,HPCAL4,TRMO,CSPG5,B3GAT1,SYT17,ALDH1L1,GNAL,GNG3,PRUNE2,GRIK3,SHISAL1,KCND3,KCNF1,MAOB,KITLG,MT1M,LYRM9,NTRK3,PDE4D,RETREG1,PPARA,MED1,PPP1R1A,PRKAR1B,TMEM231,MARCH1,RGS3,RGS12,SCN3A,ZNF334,SLCO1A2,CEP68,DNAH7,TLR4,RUNDC3B,KCNAB1,KAT6A,JPH3" Drug 6694_DN Loxapine succinate [27833-64-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ASIC1,MRTFA,APP,SHROOM2,PDE8B,MYRF,KRIT1,CLU,ABCG2,TENM4,ARHGAP24,ARMCX2,RUSC2,SGSM2,RABGAP1L,EDIL3,HSD17B14,ETV1,PDLIM5,FYN,INPP5K,GPM6B,GPER1,GPR37,GUCY1B1,MEF2C,MMP16,NDP,NOS1,PDE4B,PDPK1,RETREG1,PPP2R5C,GRAMD1C,PTHLH,PTN,PTPRN2,FAM120C,FAM184A,BEND5,GAL3ST4,KDM4D,MYH15,TNIK,MAPK8IP3,TCF4,TCF7L2,TRIM2,DOCK9,DNAH7,GPR161,TK2,XRCC4,TRIM9,KCNAB1,MPPE1" Drug 2766_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "ADORA1,ADORA2A,AP2A2,OSBPL1A,LTBP4,ALK,APBA2,APLP1,PPFIA3,CAMK2G,ARHGAP33,FADS2,HOMER3,SH2B1,CRY2,SDC3,INTS1,DMPK,SLC12A6,RASGRP2,F5,C1orf61,CAMKK2,PRRC2B,GPER1,GRIN1,CELF3,DHX35,ITGA7,MAP4,CDK18,PLTP,MBOAT7,RIPOR1,KCTD17,EMID1,FAM102A,FAM214B,KDM4B,TEX2,ARHGAP26,CAMTA2,SAMSN1,FCHO1,NCDN,ARC,EXOC7,IQCE,ARHGEF12,HIF3A,PIK3R5,HIRA,MICAL1,WIPF1,ZNF74,VPS35L" Drug 3293_UP Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "NDRG2,KIAA1324,BIN1,APC,CDK10,C5,CALB2,CCNT1,FOXN3,RAB28,HOMER3,PICK1,CTIF,MFAP3L,DTNA,EGFR,EIF4G2,EN2,F3,FAM198B,FHL1,SCARA3,FOXG1,AGAP2,TMEM8B,RND1,GNG3,NR3C1,INPP1,KHK,ZNF862,NNAT,NPR2,PLTP,LRP12,MAPK7,SAMD9,ZMAT4,RAVER2,DOCK10,PDZRN3,KIF21B,TSNAXIP1,ABCC8,ARC,DAAM2,TRIO,FLRT2,VLDLR,XRCC4,SPHK2,REEP1,ZNF189,SLC30A3,SCG2,ITM2C" Drug 3191_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "AMPD3,BIN1,ASCL1,RGS11,BAIAP3,CFAP410,HAP1,NEURL1,ARHGEF2,NRXN2,IFFO1,CPS1,DGKB,SPOCK2,JAKMIP2,SV2B,TMCC2,DRD1,ST8SIA3,RASGRP2,OLFM1,SORBS1,FYB1,HBS1L,GPR162,GFAP,GPM6B,NR3C1,WIF1,JAK2,VWA5A,MITF,MSR1,MYCN,NCAM1,NPPA,OLR1,PIK3CD,PLTP,PKN2,PTX3,RFX3,KLHL11,KANSL3,SLC9A5,SLC14A1,LIMCH1,EPB41L3,TAC1,TBCEL,PCDHGA1,RIMBP2,R3HDM1,TRIO,SCG2,ITM2C" Drug 5773_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.14E-06 2.03E-01 8.10E-05 9.22E-04 56 197 "RALGAPA1,NME5,RASL11B,KIF1A,CACNA1I,CAMK2B,NEURL1,CHN2,IQCK,ARMC8,COL9A2,COL9A3,SH2B1,CRMP1,GREB1,SEMA3D,FRY,APC2,FABP7,CORO2B,FGR,HPCAL4,ATP8A2,GRM1,ADAMTS6,ATXN2L,KCNF1,KCNH2,VWA5A,NOVA1,PCBP3,PCSK2,PDE4D,GPR85,PLCB2,PTPRN2,ACSS3,CCDC40,RAD52,RET,PNMA8A,TMEM206,PRR5L,EMID1,SLC4A3,SLC1A7,SLCO1A2,OGDHL,UNC5B,RBM26,TACR1,DOCK9,TPM1,TPM3,SLC17A7,KCNAB1" Drug ctd:C513635 S-2-pentyl-4-pentynoic hydroxamic acid CTD 4.19E-06 2.06E-01 8.21E-05 9.34E-04 180 837 "CLK4,ARID1A,GPRIN1,INTS2,NME5,NR0B1,OSBPL6,TXNDC16,APAF1,APBB1,SFMBT2,ATP1A3,N4BP2L1,RIPK1,TTC9B,SEC11C,CFLAR,BMP7,ST3GAL5,CACNA1B,HAP1,CBLN1,USP2,CDC27,EVI5L,CHGA,EPS15L1,NGEF,FADS2,TMEM184B,GAL3ST1,ABCG1,FEZ1,PHACTR3,GPRASP1,TM9SF4,SCRN1,IP6K1,ARMCX2,C2CD2L,DNM1,ABI1,GOLT1B,SEZ6L2,ATL1,KLHL5,EFNA3,RASA4,AASS,EIF5,ELAVL2,PCOLCE2,STARD3NL,EFS,KATNAL1,REEP2,WAC,DLC1,SPSB4,MAD2L2,UBE2E3,SYNCRIP,TMEM107,HVCN1,GPR153,FUT9,TPPP3,OGA,PHYHIPL,ACSS1,CYP46A1,RUNDC3A,TXNL4A,SPIN1,TNRC6A,PRDM5,RNFT2,MAP4K5,RASSF8,HBA1,PADI2,NXPH3,FRMD5,ELOVL5,MSL1,NKD1,ZIC5,RBPJ,LIX1,IL11RA,ITPKA,METTL21A,KCNK1,KCNK3,KCNN1,MAT2A,AQP11,MDM4,AFF1,SESN3,N6AMT1,PCBP3,NRDC,PFKFB2,KCTD15,ST8SIA5,JAKMIP1,SLC25A23,MAPKAP1,SEPT4,MINDY2,RASGEF1B,PRKACB,CEP41,MAPK8,PRPH,GDPD1,SNRK,ELOVL2,PTPRN,RIPOR1,PPP2R3C,RAB3IL1,BEND5,ERI2,RGS10,SEC61A2,MYH14,SGSM1,RYR1,SALL1,RASA3,FUZ,PEX26,SIRT2,KBTBD4,SLC20A2,EPC1,SMARCE1,PALLD,SON,ZCCHC24,SOX10,ERC1,SPTAN1,SPTB,ITPRID2,TTBK2,STAC2,ADHFE1,PHLDB1,JMJD6,SYN1,ARC,DMXL2,ZEB1,DOCK9,TNS2,HIF3A,TEX15,SIRT1,GPR161,TMPO,SYNPO2,TRH,PPIL6,TSC2,UBE2H,UCHL1,DNAJC12,PITPNB,MEAF6,ZIC3,ZNF24,SLC38A1,SLC17A7,WNK2,CERS6,AAAS,FRMD6" Drug CID000000702 ethanol Stitch 4.19E-06 2.06E-01 8.21E-05 9.34E-04 180 837 "ASIC1,ACHE,TKTL1,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADRB2,ALAD,ANK1,APOC1,APOC2,SPTBN4,ALDH7A1,ATP6V0A1,LDHD,CACNA1I,CA4,CA8,CA12,CACNA1B,CACNA1D,CACNA1E,CACNB2,CACNG1,CALM1,NGB,CCK,KRIT1,CD86,LRBA,DLGAP2,NOG,ASIC3,CHRM1,CHRNA4,CHRNB2,NRXN3,CNR1,CNTFR,ENTPD4,CRHBP,CS,CSF2RA,PLCXD3,GPSM1,DBI,DCT,GRIN3A,DRD1,AASDH,EDN1,EDN3,EGFR,EPB41,COQ7,STX2,ERBB2,ERBB4,PPP1R1B,POLK,PCYOX1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,ACSS1,GCK,GFAP,GFRA1,GFRA2,GGT7,GGT5,GK,GLRB,GPT2,GPD1,GPD2,GRIA1,GRIA2,GRIA4,PLCD4,GRIN2C,GRIN2D,GRM3,GRM5,GSTM5,GSTT2,HBA1,KLF12,TNFAIP8L3,MYLK2,IGF1,IGFBP1,IL6ST,IL12A,ITGAM,JAK1,JAK2,KCNJ3,KCNMA1,L1CAM,LIFR,MAG,MBP,MTR,NOS1,NPY,NPPA,NTRK2,NTRK3,OGDH,OPRL1,PC,PDCD2,PDYN,PENK,PFKP,PIK3C2A,PIK3CD,PIK3R1,PKM,PLCB2,PLCD1,PMS2,POLG,PPARA,PPP2R2C,PTPA,PPP2R5E,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PPP2R3C,ACSS3,REV3L,MAPK12,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,FNDC3A,SCN3B,SPP1,PEG10,SPTAN1,SPTB,CLSTN2,SST,APOM,ADHFE1,MLC1,PLCB1,SYT1,TACR1,SMG6,TK2,ZFP91,PIK3R5,TRH,CA14,TTPA,ZNF142,SCG2" Drug 7530_DN irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.20E-06 2.06E-01 8.22E-05 9.35E-04 51 174 "MAP4K3,APBB2,SHROOM2,NUMB,ATP2B1,ARHGEF7,MAP7,NIPBL,DYRK1A,TAOK3,SYNCRIP,AGFG1,BRINP3,DIPK1A,JAK2,ARHGAP12,MEIS1,NF1,CNOT4,PTK2,REV3L,ATXN1,ITSN1,KIF16B,AMBRA1,CHD9,ATF7IP,CDK5RAP2,TMCC1,PDZRN3,DOP1A,CDK19,SRPK2,CLASP2,ERBIN,SYT1,ANKRD28,ANKRD12,EHBP1,TCF7L2,CLASP1,WDR7,DOCK9,PUM2,FRYL,TIAM1,PARD3,TRIO,TRPS1,SSBP2,JMJD1C" Drug CID000003206 EHNA Stitch 4.31E-06 2.11E-01 8.43E-05 9.59E-04 31 87 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,ADORA3,AMPD2,AMPD3,APC,NT5C3B,ALDH7A1,ENTPD2,DNAH9,AHCYL1,GUCY1A2,GUCY1B1,NBL1,NPR2,PDCD2,PDE1C,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDE1B,TMEM132D,DDN,AHCYL2,SLC17A7,SLC17A6" Drug 5419_UP Methotrexate [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.35E-06 2.13E-01 8.49E-05 9.66E-04 54 188 "ARID1A,PLA2G6,AMPD3,APOC1,MARK4,ADAM23,NRP2,USP2,CDC42,RCBTB2,CHRNB2,VAX2,CNTN1,WHRN,CRY2,RIMS3,ATN1,DTNA,EGR3,DLC1,FHL1,HPCAL4,FYN,SESN1,RND1,GLYR1,RAB30,POLL,GRM1,MYL3,NACA,NRGN,MTRF1L,MAPK10,RASGRF1,RFX2,TTLL7,PNMA8A,ASAP3,RPH3A,OGDHL,SMARCD3,MAPKBP1,RBM34,WDTC1,ARHGAP26,ARHGEF9,KIAA1107,PCDHGA1,TMOD1,METTL3,UCHL1,KCNK12,ZFP37" Drug 5702_UP GBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.35E-06 2.13E-01 8.49E-05 9.66E-04 54 188 "NDRG2,KIAA1324,CNTNAP1,MTMR3,CACNG1,KALRN,HAP1,RAB33A,PPP1R16B,RIMS2,EDRF1,SPATA2,EDNRA,EFNB3,EGR3,ING4,COQ7,FGF13,C1orf61,FOXF2,RND1,GRM8,GSN,NXPH3,IRF8,INPP5B,KCNJ5,KPNA5,MAOB,ADAM11,MDFI,MOBP,NLE1,PLCD1,TNPO2,PPP5C,RAD52,RASGRF1,TCP11L1,SYNDIG1,ZNF821,SLC2A5,FAIM2,TNIK,MCF2L2,SAMSN1,ACSBG1,JMJD6,VAMP1,THBS4,TNS1,VLDLR,SPHK2,SSPN" Drug 4845_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.35E-06 2.13E-01 8.49E-05 9.66E-04 54 188 "ARID1A,PKP4,MADD,ALDH4A1,ATP2B1,MTMR9,ADAM15,KRIT1,LRRFIP1,CSNK1E,SOCS5,CTNND1,ARHGAP32,MAMLD1,EIF4G1,TESK2,POLR1B,PCYOX1,USP21,GOLGB1,ARHGAP19,INPP5B,MBP,SLC11A2,CCSER2,PLEC,RC3H2,PMS2,CNNM2,SIDT1,ZSCAN32,PLEKHB2,MORC4,RGS10,CHD9,PEX26,PALLD,TMCC1,CDK19,ZBTB43,TROVE2,PRRC2C,TACC1,TBL1X,SATB2,AHCYL2,CBX5,KAT6B,TRIO,UBTF,NSD2,CLDND1,WNK1,PRDM2" Drug CID006450546 gavestinel Stitch 4.35E-06 2.13E-01 8.50E-05 9.67E-04 14 25 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug ctd:D000535 Aluminum CTD 4.49E-06 2.20E-01 8.76E-05 9.96E-04 363 1869 "KCNH8,ABR,SYN3,ACHE,ACLY,CLK4,GPRIN1,TMEM132B,DSCAML1,RNF157,ADD2,ERMN,BEND6,SLC24A4,ALAD,USP35,MARCH4,BBOX1,UNC79,ALK,DOC2A,AMPD2,SEMA7A,PI16,MYH7B,USP28,PPFIA2,CNTNAP1,APLP1,BCAS1,APP,CPNE5,AQP6,MIER1,SFMBT2,PPP4R4,CASK,ARHGDIA,ARRB1,ASPA,CCDC74A,CAPRIN2,DACT3,GPR146,ZNF599,GYG2,CACNA1G,CDK5R2,IL33,CACNB4,CACNG1,CALB2,KALRN,CAMK2A,CH25H,SLC5A11,CERS5,CCNT1,P2RX6,CD38,ENTPD6,LONRF2,ARHGAP33,TIGD7,SOCS6,CHM,SYNPR,TAOK2,NRXN1,CLTB,NGEF,FBXO7,LY86,CCDC151,HOMER3,CNTN1,COL4A5,BAG4,MROH8,ARHGEF10,MICAL2,SLITRK5,ERC2,USP6NL,HDAC9,KIAA0513,CNIH3,MFAP3L,SV2B,SRGAP3,ARNT2,CHRDL1,EXOG,MED12,DRD1,USH1C,ST8SIA3,HIPK3,CNNM1,HEYL,MRO,PLXNC1,SORBS3,TENM1,ELN,EMX2,OLIG2,ENO2,EPB41,EPB41L1,RASGRP2,KCNMB2,ENPP6,RAB9B,IGSF6,MRPL10,RTN3,RCSD1,RASL12,HSPA12B,F8,ABCA8,CACNG3,ACSL4,ZIC4,SCML2,CORO2B,FKTN,ZNF589,OLFM1,SPSB4,AGAP2,ANKFY1,SYT3,FOLR2,CELF1,ST6GALNAC3,BRSK1,FYB1,GABRG2,NEK6,GHDC,DNER,GFAP,RUNDC3A,GLYR1,GPD1,PRUNE2,ATF7,LILRA2,GPR17,MCHR1,GPR26,TMEM121B,RAPGEF4,DIDO1,PLCD4,GRID1,PLPP7,GRIK1,GRIN2C,BTN2A1,ZBTB49,LINGO1,ADAMTS6,HAS2,PADI2,NXPH2,PACSIN2,NCKAP1L,CELF5,HTR5A,IGF1,ITIH2,SLC35G1,KCNA6,KCNC1,KCNJ3,KCNJ16,KCNN1,KIFC3,KIT,KLRC3,LAMA2,SFXN5,LMO2,LSAMP,SMAD9,MAN2A2,MAPT,MEF2C,AFF1,XRRA1,MN1,MOV10,CPNE9,SESN3,MSR1,MTTP,MTR,MDGA1,HS6ST3,FXYD7,NEFM,NEFH,NEK1,NF1,ALDH1L2,NINJ2,NODAL,NOS1,NPY,DNHD1,LRIT2,CLEC9A,NUMA1,OGDH,OPCML,OPHN1,OPRL1,ZDHHC22,TREM2,GLIPR1L2,SNTG1,PCSK1,PDCD2,PDE1A,PDE4B,FAM98B,PHKG1,PIK3C2A,PIK3R1,XRN1,PLCD1,PLEC,TRHDE,RC3H2,SCHIP1,PRRX1,MAGEL2,FAT3,NXPH1,IRX1,PRKCB,MAPK3,PROX1,PSD,PTHLH,PTH1R,STK32A,PTPRH,PTX3,SH3TC2,DBX2,RBBP6,DUSP15,MORC4,FIGN,RFX2,KIF7,RLBP1,RNASE1,RERGL,DCUN1D2,MYH14,RAVER2,CARF,ROBO2,RORB,CCDC102B,FAM161B,KCNIP1,TRAPPC13,S100B,ASIC4,ELMOD1,MRAS,FRMPD1,SLA,SLC1A2,SLC1A3,SLC1A6,DHX30,LRRC55,SLC6A8,SLC6A11,SLC8A3,SHANK2,KBTBD4,SCMH1,SLCO1A2,EPC1,ZFP1,OGDHL,DMRTC1,RCOR3,SNCA,KIF13A,IDI2-AS1,C11orf87,ATP10B,COLGALT2,NKAIN2,APOM,NEK4,SEPT8,RGL1,STXBP1,RHBDL3,NUDT10,ANKRD28,ADGRL3,AGTPBP1,TMEM136,TBX15,TMEM151B,PCDHB7,PSD3,ARHGEF12,PCDHA7,PCDHA2,FRYL,TF,TGFBR3,HHIP,CDH22,THRA,TNFRSF1B,KAT6B,LILRA4,TPM2,ZNF384,RGMB,TRIO,TRPM2,ZMYND8,KCNE5,RFTN2,SGK3,FLRT2,LAT2,NSD2,WNT7A,ETNPPL,USP32P2,ZFP41,ZNF142,ZBTB16,ZNF225,SLC30A4,EVI5,SIGLEC10,PCDH15,PLSCR4,HRASLS,ZNF37BP,RNF170,TTC7A,IFT88,NETO1,SOCS4,SLC4A10,SPATA13" Drug 4619_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.52E-06 2.22E-01 8.83E-05 1.00E-03 52 179 "GRAMD1B,BIN1,GAS7,FAM131A,BRINP2,BCL2L2,C5,MAP7,ADGRG1,WHRN,CREM,AKAP12,HAPLN1,ABCG1,CSF1,MICAL2,CTH,ARHGEF4,DBT,PITPNC1,ARNT2,USH1C,EDNRA,SGK2,SPEG,AGAP2,TACC2,PRUNE2,GPER1,ACOT7,JAK2,MIA2,OPRL1,PDE4B,PDGFRA,SMOX,PMP22,FA2H,PTHLH,GSTCD,RTN1,FAM102A,ST6GAL1,PHLDB1,JMJD6,ADGRL3,TBL1X,PCDHGB6,TPM2,SSBP2,PMEPA1,KCNAB1" Drug CID000028558 L-BMAA Stitch 4.57E-06 2.24E-01 8.91E-05 1.01E-03 18 38 "POLL,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID000068736 CGS 19755 Stitch 4.57E-06 2.24E-01 8.91E-05 1.01E-03 18 38 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KITLG,NTRK3,SLC6A9" Drug 3973_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "ASIC1,SLC12A5,NME5,APC,APLP1,APOC1,DNAH17,ASPH,SLC4A4,CFAP410,CACNA1A,USP2,CBFA2T2,CHM,CNTFR,RCHY1,CPS1,CSF1,CNTNAP2,SDC3,PPP6R2,MAGI2,DMPK,EDNRA,EFNB3,ANKMY1,ZNF589,FER,FHL1,SCARA3,CGREF1,GPR153,SRCAP,GPER1,GRIK5,KCNJ5,MSR1,ZNF862,NDUFA5,PLCD1,FAM120C,RAB3A,ZDHHC14,MSANTD2,RGS12,EPN2,EMC1,TROVE2,THSD1,STX1A,KAZN,ROBO3,CRTC1,WIPF1,ITM2C" Drug 3347_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "ASIC1,ARID1A,ADORA1,AGT,NME5,ARHGDIG,ATP2B3,BAIAP3,CFAP410,RUNX1T1,CACNA2D2,LHX2,TPP1,STOML1,NRG2,NCOR2,CSF1R,PLCH2,CNTNAP2,RUSC2,DRD1,ERCC2,ZNF391,CACNG2,ZNF589,KIAA1109,FHL1,DLL3,GCNT2,LYVE1,RND1,GNAS,GRM1,IL6ST,MAG,NF1,SNTG1,LRP12,TNPO2,CEP41,SAMD9,FAM184A,RPS6KA2,EMID1,SH3BP2,BTBD7,KDM4B,JMJD6,ABCC8,ARC,DOCK9,UBE3A,SLC30A3,SLC17A7,TIGD6" Drug 2561_UP Dicumarol [66-76-2]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "ABAT,ANK3,APOC1,LGR5,ARHGDIG,CACNA1G,CA8,CACNB4,CACNG1,CDH2,DLGAP1,JAM2,LHX2,ZFYVE9,NRG2,CSF1,MICAL2,RIPOR2,DAPK3,SPOCK2,KIAA0319,SPOCK3,EXOG,TRAPPC9,DRD1,EFS,DLC1,CAMSAP1,NSG1,GLI2,GNAL,GPM6B,GRIK2,KLF12,ITIH2,KCNA2,KCNB1,KCND3,KCNJ5,PDE4D,PMP2,PPP1R1A,CNNM2,PTPRB,KHDRBS2,ZNF821,SLC1A7,SHANK2,SYT5,DNMBP,TBCEL,PCDHGA10,SEZ6L,TRO,DNALI1" Drug 2852_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "NDRG2,CDC42BPA,CDC14B,PLA2G4C,CDK13,ATM,CFLAR,CA4,CACNB2,ZFYVE9,SLC4A7,NECTIN3,PDE4DIP,DCAF8,DBT,EXOG,DMPK,DUSP9,SIDT2,CELSR3,SORBS3,STX2,EZH1,KIAA1109,FAM49B,SRCAP,GLS,STON1,ICA1,IL6ST,INPP1,KCNH2,KCNJ3,LIFR,MITF,NF1,PCDH9,SLC25A23,LRP12,MBOAT7,MINDY2,CCDC40,RAD52,SEC14L1,SELL,NUBPL,RPH3A,SLC20A2,KIF13A,SOX3,IQSEC2,PSD3,ZMYND8,ZKSCAN5,ITM2C" Drug 6697_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "TRMT9B,AMT,CDC42BPA,ANK3,KCNAB2,APP,CDK10,MARCH3,ALDH4A1,SLC4A4,NRP2,ST3GAL5,FOXN3,CHN2,ZFYVE9,WHRN,CREM,NCOR2,TENM4,ARHGEF4,ZFYVE16,CNIH3,RABGAP1L,DYNC1I1,FAM13A,AASS,COQ7,ETV1,SCML2,FGF13,AFF2,TDRKH,CNTRL,GUCY1B1,HNMT,KIF5C,TM6SF1,SCAMP5,NDP,NUMA1,SETD4,OPCML,PPP5C,GRAMD1C,PTHLH,RALGDS,RPS6KA2,ASAP3,FBXO11,TCF7L2,TK2,CBX5,LMF1,XRCC4,EMSY" Drug 2275_UP Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "SYN3,AK2,CDC42BPA,ATM,FGF17,CFLAR,CACNA1I,CACNG1,SEPT7,TAOK2,WHRN,TCEAL2,SEC14L5,CTIF,TMCC2,ST8SIA3,EDN3,EPHB1,KCNMB2,NRN1,ZNF589,C1QL1,GPR75,ATF7,GPER1,GRM7,CELF3,ATXN2L,IL6R,ITGAM,KCNJ4,MAOB,MMP17,MYL3,PFKFB2,PLP1,PTAFR,PTCH1,SELL,FRMPD1,ASAP3,ST6GAL1,NLGN1,SLC1A7,BTBD7,ZSWIM8,BEX1,VAMP1,DMXL2,CRTC1,ICAM5,TNS1,TRPC1,ZMYND8,UCHL1" Drug 1647_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "RBM10,SPARCL1,AMH,BIN1,CDC42BPA,HIP1R,LRRFIP1,LHX2,CLU,HOMER3,PICK1,SLC4A7,CSNK1E,OSBPL3,RIMS2,SMG7,ERAP1,SYT17,MALT1,GNG3,GRB10,L1CAM,VWA5A,MAOB,MAP4,CDK18,ENPP2,RETREG1,CDIP1,PACSIN1,PRKAR1B,PTCH1,PTHLH,KHDRBS2,SH3BP2,PEX26,ARFGAP1,MAPKBP1,SOX3,ZCCHC24,SPTAN1,IQSEC2,DIP2A,STX1A,TBL1X,WSCD1,TRIM2,AHCYL2,WBP2,CADM1,UBTF,VGF,MICAL1,WNK1,PRDM2" Drug 7014_DN Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "OGT,CDC42BPA,APC,NCOA1,ATM,ATP2B1,MTMR9,ADAM15,SYNJ1,LARGE1,QKI,KIAA0586,C2CD2L,PARD6A,SGSM2,DNM2,EIF5,ERBB2,VPS26C,ECSIT,FGFR1,PDLIM5,CELF1,INPP5K,GPR19,BTN2A1,PADI2,KIF5C,MAN2A2,MEIS1,NFYA,FSD1,C1orf109,REV3L,SEC61A2,TCP11L1,LGR4,SAFB,SEC14L1,SUPT20H,KIF16B,KDM4B,CEP68,FAM168A,DMXL2,SATB2,TCF7L2,ATP13A2,CABIN1,ZNF384,TSC2,CLDND1,MPPE1,FZD3,PHTF2" Drug 1961_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HG-U133A Broad Institute CMAP Down 4.62E-06 2.27E-01 8.98E-05 1.02E-03 55 193 "ABHD6,NDRG3,PLA2G6,BIN1,PPFIA1,PDXK,ATM,SLC4A4,MTMR9,BLM,CFLAR,PTBP2,CAMK2B,MAP7,NFS1,ARHGEF2,TAOK2,EPS15L1,DCAF8,ZFYVE16,SPOCK2,DTNA,EFNB3,SORBS3,ETV1,ZNF589,USP21,OGA,ERAP1,PCLO,GRB10,GRIK5,MAP4,NEK1,PAK3,MAPK3,CNNM2,PTPRE,GTDC1,RIC8B,MYH14,SUPT20H,URGCP,SLC11A1,SMARCA4,UNC5B,SRPK2,ATP10B,FCHO1,CEP68,SYNE2,VAMP1,TCF7,TRIO,HSPBP1" Drug 3540_DN Quinic acid [86-68-0]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ARID1A,KIDINS220,AK2,AMPD3,BIN1,PPP4R4,PDE8B,RIPK1,KIF1A,CDK5R1,CAMK2G,RAB28,NECTIN3,CREM,CRY2,RIMS3,RUSC2,TRAPPC9,EN2,LRRC23,NCALD,ANKMY1,F3,BAIAP2,USP19,CNTRL,SPACA9,LMO2,MAPT,MIA2,ADAM22,NEK1,NUCB1,OPCML,PDPK1,PRKAR1B,RALGDS,SEMA6D,SBF1,ATXN1,ANKRD6,ABLIM3,SLC20A2,KIF13A,WDTC1,THSD1,ELOVL4,PHLDB1,VPS13A,ASTN2,ZEB1,PSD3,TMOD1,MICAL1,WIPF1,EMSY" Drug 6078_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RALGAPA1,ASIC2,SEMA6A,PRX,ASPA,CHRNA4,CYBB,SPOCK2,ATN1,EDN1,LRRC17,REEP2,FGF1,SRCAP,PCDH17,LPAR4,GRB10,ADAMTS13,GRIK5,AP4S1,CELF3,ATXN2L,ICA1,KIT,SMAD1,MYO7A,NFIX,NTRK2,TREM2,CDK18,PDE4A,ENPP2,PFKFB2,CAMKV,EPN1,POU3F4,PPP5C,CEP41,MAPK8,SAMD9,PTHLH,C1orf54,RGS12,EMID1,SLC2A5,SLC11A1,SHANK2,DOK5,INKA2,VAMP1,CUX2,PSD3,TRPM2,PDIA2,WIPF1,SLC30A3" Drug 4397_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ASIC1,NDRG2,KIDINS220,PLA2G6,ATP2B2,SCAPER,CFAP410,CACNA2D1,RHBDL1,CD86,DGKI,TAOK2,CLCN4,NCOR2,ARHGEF10,CNTNAP2,DNAJC6,ETV1,F5,OLFM1,FGR,GAD1,SRCAP,GRIK1,HAS2,HPSE2,VWA5A,MDFI,ADAM22,NPTX2,OPRL1,PCDH9,CDK14,STRN3,PPARA,PTAFR,FAT4,ZMAT4,SH3GL3,SLC2A5,KANSL3,SLC11A1,PEG10,COLGALT2,ZFR2,TAL1,WSCD1,SLC35G2,ICAM5,HEY2,TRPC3,VAV2,LAT2,ITM2C,PLSCR4,AP3B2" Drug 7256_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "LGR5,SLC4A4,RIPK1,BID,CDK5R1,CBFA2T2,ADGRG1,CNOT8,RAB28,NRXN3,ZFYVE9,SULT4A1,NCOR1,ARHGEF10,MICAL2,TBC1D5,DYNC1I1,EFNA3,FAM13A,REEP2,TESK2,FER,KIAA1109,BAIAP2,AMOTL2,TRMO,CSPG5,NCKAP1,GLS,GPR17,SHISAL1,KIF2A,NF1,NFYA,SLC11A2,CDIP1,RAB3A,MYH14,PPP1R9A,FNDC3A,BCAN,EMC1,CAND2,ZBTB43,SPART,WWC1,IQCE,ZMAT3,ZNF34,TK2,XRCC4,ZNF142,SCG2,EPM2A,FZD3,ACTR3B" Drug 7532_DN CP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AK2,FAM135A,PPFIA3,CFLAR,CACNA1D,BRSK2,MAGI1,B4GALT6,LHX2,HOMER3,BAG4,DCT,TRAPPC9,USH1C,ELN,COQ7,LRRC23,EFEMP1,DLC1,TMEM8B,MALT1,LYVE1,GLYR1,GLS,NXPH3,ATXN2L,HSF2,ICA1,JAK2,NPR2,PALM,PCDHGC3,KCTD15,SMIM7,MINDY2,PTAFR,PTPRG,ZDHHC14,NEK11,TCP11L1,RPS6KA2,SH3BP2,SLC1A2,SLC6A8,RAP1GAP2,TROVE2,THSD1,PCDHA6,SLC44A1,CDK20,TRO,TRPC1,FAM155A,LMF1,XRCC4,EPM2A" Drug 3885_DN Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ABHD6,MRTFA,BIN1,APC,FAM131A,PPFIA3,APP,MARCH3,ALDH4A1,SLC2A11,KIF1A,SYNJ2,MAGI1,RIMS3,CTIF,DNM1,DMPK,DRD1,ATN1,EDNRA,SORBS3,ING4,FAM198B,GNAS,MUM1,IL6R,MAOB,MMP17,GIT1,NPTX1,RETREG1,MAPK8,RAB3A,RAB3IL1,CEP97,ZCWPW1,ROM1,ASAP3,LIMCH1,WDTC1,ZNF423,ARHGAP26,IQSEC2,MAPK8IP3,TTBK2,VPS13A,KIAA1107,SMG6,HEY1,TK2,CABIN1,KCNK12,ZBTB14,ZIC3,NDRG4,WNK1" Drug 3785_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "SLC12A5,ALK,SEMA7A,APC,ADGRB2,BCHE,IL33,CACNG1,RUNX1T1,CLCN4,LY86,TCEAL2,CSF1,TENM4,MICAL2,DCAF4,KIAA0513,CTIF,RABGAP1L,TRAPPC9,DUSP9,LPAR6,SORBS3,CDKL3,FGFR1,HPCAL4,FAM49B,GAD2,ATP8A2,NEU3,GFER,CACFD1,SHISAL1,TJAP1,KCNB1,MIA2,NPR2,NTRK2,CLDN11,PAK3,SNRK,PTHLH,SUSD4,GAL3ST4,RGS4,RGS7,TMEM206,NTNG1,TSNAXIP1,UNC5B,SPTB,TRIM2,TNS1,CDK20,LAT2,GAN" Drug 6481_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADD2,KIDINS220,ALK,BEGAIN,PPFIA3,ALDH7A1,N4BP2L1,PROM1,SCAPER,MTMR3,SGCE,CACNA1I,CA4,CACNA2D1,WHRN,COL9A3,TENM4,SDC3,DCAF4,EFNB3,RASGRP2,KAT8,FER,ALDH1L1,PCDH17,SPACA9,GRIK5,CACFD1,GRM8,GUCY1A2,GPR45,SYNPO,HPCA,DHX35,ICA1,IGFBP1,ITIH2,KCNJ4,MOBP,PALM,PLCD1,EPN1,LRP12,PTHLH,RAD52,RGS7,FRMPD1,ST6GAL1,CNKSR2,PKNOX2,AJAP1,KAZN,UGT8,WIPF1,SLC26A10,SLC17A7" Drug 4167_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "DPF1,AGT,AK2,BEGAIN,CCDC181,ATP1A2,CFLAR,CACNA1I,CACNA2D1,CALB1,KALRN,ADGRG1,CHI3L2,B4GALT6,CLCN4,STOML1,NRG2,ARHGEF10,DAPK1,RUSC2,DMPK,EDN1,REEP2,PTK2B,FOXG1,FAM49B,CAMKK2,ZNF44,ALDH1L1,GRM7,GUCY1A2,ITGA7,MOBP,ZNF862,NNAT,NPR2,NTRK2,KCNK10,GPR85,PPP1R1A,MAPK7,RAB3A,KCTD17,SCN8A,ST6GAL1,SLC1A7,PKNOX2,SMARCD3,SP4,ATP10B,KIAA1107,ICAM5,R3HDM1,OSBP2,SLC17A7,ITM2C" Drug 3505_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "C1QTNF1,ALCAM,ATM,CADM3,CFLAR,SCAPER,GYG2,MYRF,CFAP410,CDH2,FOXN3,IFFO1,EDRF1,DOCK4,JAKMIP2,PLPPR4,TMCC2,DTNB,EDNRA,PLXNC1,TENM1,MTSS1L,DCTN2,GAP43,GLS,GRM7,GUCY1A2,ICA1,NDP,PCDH9,PFKFB2,PIK3R1,STRN3,PACSIN1,MINDY2,GRAMD1C,TRIM68,TCP11L1,SCN2B,ITSN1,SH3GL3,FAM214B,CCDC88A,CXXC4,SOX2,IZUMO4,PCDHGA10,PSD3,PCDHA5,TIMP4,TRIO,XRCC4,GDPD5,ITM2C,FAM13C,SSPN" Drug 7323_DN Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ABAT,AP2A2,APOC1,EIF4G3,C5,LRRFIP1,VAX2,CREM,ENTPD4,SDC3,RUBCN,KIAA0586,DBT,TSPAN5,SORBS3,MRNIP,DMTN,BAIAP2,FAM49B,SYT17,INPP5K,GLS,ARHGAP19,ACOT7,JAK2,KCNH2,LSS,MPP2,ZNF862,NFYA,RETREG1,PLXNB1,POLG,PTPN13,RAB3IL1,CEP97,ZCWPW1,PPP4R3A,ZKSCAN3,LHPP,DIP2A,STX1A,NSFL1C,ATP11A,TACC1,EXOC7,WWC1,TBL1X,TRIM2,AHCYL2,BEX4,CABIN1,TPD52,TPM1,NSD2,WIPF2" Drug 5780_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RALGAPA1,NME5,APAF1,ATP2B2,KIF1A,MYRF,BTRC,MAGI1,CHN2,COL9A2,AKAP5,IPCEF1,ARMCX2,PLPPR4,ECM2,EDIL3,EDN1,PLXNC1,DMTN,EZH1,FABP7,CORO2B,FGF1,OLFM1,PDLIM5,NSG1,GAB1,ATP8A2,SRCAP,ATXN2L,SCIN,JAK2,KCNH2,AFF1,NOVA1,GPR85,POU3F4,PPP2R2B,PKN2,MAPK8,PTN,ACSS3,CCDC40,RGS4,KCNIP1,KIF21B,SEMA4A,KIAA1107,ZFPM2,TK2,TLL2,TLR4,LILRA4,CA14,WIPF1,KCNAB1" Drug 3215_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ARID1A,NDRG2,SPARCL1,ALCAM,BCAS1,CDK13,ALDH4A1,ATP1A3,ATP2A2,ADGRB1,CFLAR,SGCE,BAIAP3,BTRC,CA4,ARHGEF2,ADGRG1,FAM189A2,BAG4,ARHGEF4,ECE2,NOS1AP,MFAP3L,SPOCK3,EFNB3,GAD1,ERAP1,KLF12,IL6ST,INPP5B,KCNN1,MDFI,MMP16,MSR1,TAGLN3,NF1,OMG,PDE1C,PPARA,PPP5C,RIPOR1,CCDC40,ZNF493,TCP11L1,ASIC4,LIMS2,ARHGEF40,SLC14A1,CDK19,SPX,SLC44A1,RIMBP2,TNS1,TPM2,TRPC1,SLC17A7" Drug 7421_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AK2,PLA2G6,SEMA6A,AMH,APBB2,CDK10,ARRB1,ALDH4A1,ATP6V0A1,MPDZ,CDK5R1,ST3GAL5,CFAP410,PLEKHB1,ZFYVE9,STOML1,QKI,AKAP7,VCAN,DZIP3,RIMS3,GIT2,DTNA,TOM1,HIPK3,ABI2,EIF5,ING4,B4GALNT1,SRCAP,CSDC2,MSL3,POLL,GNG3,ATF7,LPAR4,SPACA9,RASSF8,INPP5B,MMP16,PDE1C,PTPRB,PEX5,RGS12,SLC2A5,MAPKBP1,SNCA,ZCCHC24,EMC1,SPTAN1,TMEM121,PIK3R5,RBFOX2,UBE3A,HPS4,PHTF2" Drug 5507_UP Sulfaphenazole [526-08-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ABHD6,ACTN2,BIN1,CDK10,ARRB2,PLA2G4C,ALDH7A1,RIPK1,CFLAR,CACNA1G,CFAP410,CAMK2B,SLC16A4,CLGN,FOXN3,QKI,CSF1R,LRIG1,RIMS2,RIMS3,DPP6,DTNA,SGK2,VPS13B,NRN1,FGF13,GNAO1,GNG3,GPM6B,HNMT,ITIH2,KHK,LIG4,MMP17,NFYA,NTRK3,PLCD1,SLC25A23,STRN3,LRP12,MAPK8,RELN,ELOVL2,PTPRE,ZMAT4,ZFHX4,SYBU,ANKRD6,IZUMO4,THSD1,CEP68,STX1A,PLCB1,WSCD1,KIAA0930,CA10" Drug 3343_UP Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ACTN2,ALCAM,ALK,APLP1,DNAH17,N4BP2L1,CFAP410,NEURL1,RAB28,CLTB,WHRN,CSF1R,CNTNAP2,RIMS3,SPOCK2,EDNRA,SGK2,MBNL2,FAM198B,ZNF589,FGF13,FHL1,FLNC,SORBS1,DLL3,FYB1,GABRA2,DISC1,RND1,ADAMTS13,GRM1,TJAP1,IL6ST,KCNN1,KCNQ3,NF1,PDE3B,PDE4D,PGAM2,PPARA,SIDT1,ZMAT4,RPS20,SYNDIG1,RASA3,SH3BP2,ASAP3,SMARCD3,SNCA,WDTC1,TSNAXIP1,HECW1,SYT11,PSD3,TRPM2,PARP11" Drug 3414_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "DOC2A,AMPD3,APBB2,PPFIA3,RGS20,CAMK2B,KYAT1,ZMYM4,FAM189A2,DNAJB5,SNCAIP,CSF1,MICAL2,CNTNAP2,GREB1,JAKMIP2,SPOCK3,TMCC2,DMPK,DPH1,RCAN1,SUGP2,EML1,DMTN,DLC1,TPK1,POLL,CACFD1,GSN,KLF12,KCNB1,KCNQ3,LMO2,MBD1,ZNF862,NRGN,NTRK2,SNTG1,PRKAR1B,FAM120C,RAB3IL1,ZDHHC14,ASAP3,SHANK2,BTBD7,ZKSCAN3,CEP68,PLCB1,POPDC3,KAZN,PARD3,TPD52,RUNDC3B,ZBTB38,EMSY,GDPD5" Drug 2887_DN Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AMPD3,SEMA4G,NUMB,ALDH4A1,CDK5R1,CAMK2G,ARHGEF1,ARHGEF2,ABI3BP,CRY2,NCOR1,PHF14,DCAF4,MFAP3L,LYPD1,EML1,DMTN,LRRC23,GPR153,HSD17B1,INPP1,INPP5B,KCNH2,MAP4,MIA2,MMP16,GIT1,LYRM9,NEK1,NF1,PMP22,TNPO2,PPP5C,ZSCAN2,RAB3A,RAD52,RGS10,RYR1,SBF1,SH3BP2,ASAP3,BCAN,SLC6A8,CXXC4,RBM34,WDTC1,ZCCHC24,EMC1,ERC1,UNC5B,SPTAN1,MAPK8IP3,TTBK2,KIAA1107,PLPPR2,MICAL1" Drug 6026_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "DPF1,TKTL1,ALK,BIN1,ARHGDIG,CDK13,MARK4,GYG2,CACNA1I,CACNA1G,CACNB2,CAMK2B,CDH2,B4GALT6,SH2B1,SNCAIP,IPCEF1,SPOCK2,PLPPR4,SPOCK3,ATN1,DUSP9,AASS,ERBB4,CEND1,BAIAP2,PRELID3A,NSG1,PNMA2,DISC1,GCK,GNG3,ATF7,GRIA4,GRM8,AFDN,MMP17,NF1,NPR2,PAX6,PDE4A,PTAFR,C1orf54,ZMAT4,RGS12,KCNIP1,ASIC4,RASA3,ST6GAL1,SLC11A1,CAND2,INKA2,JMJD6,OBSL1,CRTC1,NT5M" Drug 5416_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "KDM5D,ARID1A,NDRG2,AP2A2,PLA2G6,BEGAIN,APAF1,PRX,CACNA1I,CA4,NEURL1,CLCN4,CNTFR,WHRN,SNCAIP,ARHGEF10,SOCS5,GREB1,TMCC2,DNM1,DMPK,CDON,EFNB3,AASS,REEP2,FGFR1,AGAP2,DPYSL4,SORBS1,GAD1,GLI2,GLYR1,GLS,GNAS,GNG3,PRRC2B,NR3C1,RASSF8,NCKAP1L,ICA1,KCND3,KCNH1,KCNJ4,MAP4,MYO7A,NCAM1,PLCD1,MAPK8,RGS12,SLC2A5,OGDHL,ZC3H13,RBM26,SYT5,WNK1,EPM2A" Drug 6631_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADRA1D,TRMT9B,AMPD3,APBB2,CDK13,PDE8B,DNAH17,SLC4A4,KSR1,TAOK2,CLU,CTIF,SMG7,CDON,FEM1B,DMTN,ETV1,FGFR1,ZNF44,INPP5K,GLYR1,STON1,LPAR4,GPR37,GUCY1B1,BACH2,SHISAL1,TJAP1,KIF2A,IPO5,AFDN,ZNF862,NOS1,GRAMD1C,PTCH1,PID1,RAD52,RGS10,SEC61A2,FBXW7,SCG5,ZFP30,LIMS2,BTBD7,SNCA,GLT8D1,DDN,SYT1,ASTN2,KIAA1107,SMG6,KLHL4,TMEM121,THRA,WIPF1,NT5M" Drug 2848_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "NME5,APAF1,APOC1,BMP7,CA12,CACNB2,CACNG1,ADGRG1,RCBTB2,SLIT2,VAX2,CSF1,DCTN1,CNIH3,PLXNC1,EZH1,BAIAP2,SORBS1,GAB1,DISC1,GCNT2,AHDC1,MSL3,GPM6A,GPR22,ATXN2L,KCNH2,KHK,MITF,ZNF862,NNAT,PALM,RETREG1,PLCB2,PURG,TNPO2,POU3F2,MAPK10,RAD52,ZFHX4,RNH1,EPN2,SMTN,SLC9A5,KDM4B,ZCCHC24,SPTAN1,NCDN,ATP11A,MTCL1,TCF7L2,TK2,TRIO,PLPPR2,VLDLR,DNALI1" Drug 491_UP dopamine hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADD2,ANK2,APC,GAS7,MTMR3,CHRNB2,JAM2,CREM,ENTPD4,CTNND1,BRINP1,PLEKHA1,HSD17B14,STX2,ZNF589,CAMKK2,GABRG2,DISC1,RUNDC3A,COPS8,GRIA4,ELOVL5,KCNJ5,L1CAM,STMN1,MATK,MPP2,ADAM22,MYL3,MYO9A,NEK1,NELL2,NNAT,NPY,SETD4,PDCD2,PDE4B,PLXNB1,PTN,PTPRN,SUSD4,ATXN2,SHANK2,SLC15A2,CDK5RAP2,CLASP2,PHF24,OBSL1,PCDHA5,ACTR6,TNS1,SEZ6L,TRPC3,TMPRSS5,VIPR2,NUP214" Drug 5431_UP Budesonide [51333-22-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AMPD3,APAF1,GAS7,CDC14B,RGS9,BAIAP3,CACNA1D,CDH18,ADGRG1,SOCS6,CLCN4,SLC24A2,CSF1R,MAML1,MFAP3L,CEND1,FAM198B,GPR153,NEU3,GNG3,GRM2,HRH3,ICA1,C2orf72,KCNH2,KCNN1,KHK,VWA5A,MAP4,CD200,PDE4A,TMOD2,PRKAR1B,MAPK7,MAPK8,MAPK10,RELN,PTAFR,PTN,PTPRO,RAD52,C1orf54,SH3BP2,ST6GAL1,SLC1A7,ARHGEF40,RIMS1,WDTC1,ARHGAP26,SPTB,PSD3,PCDHA5,HEY2,LILRA4,TRPC1,AMOT" Drug 5295_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RBM10,ALCAM,LTBP4,MRTFA,ASPH,ATM,LRRFIP1,LHX2,VAX2,HOMER3,AKAP7,GPRASP1,KIAA0586,GIT2,SMG7,TRAPPC9,DPH1,DTNA,FCF1,EFNA3,MRNIP,COQ7,DLC1,KHDRBS3,SRCAP,VWA5A,NFYA,POLG,PPP5C,PRODH,GON4L,TMEM231,RAB3IL1,RAD52,SBF1,SH3BGR,ITSN1,SLC15A2,SLC20A2,COA1,THSD1,FCHO1,TTBK2,EXOC7,IQCE,TCF7,TRIM2,AHCYL2,SLC44A1,TPM1,ZNF74,EMSY,HPS4,SEMA3B,ITM2C,MPPE1" Drug 2917_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "APBB2,GYG2,LDLRAD4,CA8,THSD7A,DCAF4,ZNF337,SPOCK2,DNAJC6,DTNB,EFNA3,TNK2,APC2,ETV1,FCGRT,FGFR1,BAIAP2,AFF2,PDLIM5,GPR153,SIGLEC8,SEPT9,CSDC2,GNG4,GRIK5,GRM7,IL1RAPL1,ATXN2L,KCND3,KCNJ5,MMP16,NOS1,OPRL1,KCNK10,PDE1B,NLE1,PLEC,EPN1,SLC25A23,NECAB2,PRPH,MASP1,BCAS3,CCDC40,ROM1,SLC11A1,TMCC1,SPTAN1,IQSEC2,RAP1GAP2,EXOC7,CHST8,TK2,ICAM5,TRPC1,FAM155A" Drug 2898_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "SEMA6A,FAM131A,SEMA4G,SLC4A4,KIF1A,SCARB1,ARHGEF2,RCBTB2,ASIC3,VAX2,QKI,ABI3BP,NECTIN3,SOCS5,PDE4DIP,FAM169A,PHF14,DCAF4,NOS1AP,MFAP3L,HP1BP3,SLC12A6,OPTN,DMTN,TRAF3IP2,CNTRL,TJAP1,INPP1,MAP4,MDM4,GIT1,LYRM9,ZNF862,NF1,PCDH9,PDE3B,RETREG1,STRN3,POLG,MAPK8,PRPH,ATG16L1,RGS3,BCAN,SYBU,SLC6A8,SOX2,TROVE2,CLSTN2,EXOC7,TBL1X,CHST8,UBE3A,ZNF24,DNALI1,RNF170" Drug 6352_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADORA1,MRTFA,SEMA4G,PPP4R4,ALDH4A1,STX16,NRP2,ST3GAL5,BAIAP3,BTRC,CFAP410,CACNA1A,KALRN,CAMK2B,PLAA,AKAP7,ABCG1,PDE4DIP,CTNND2,SIDT2,EFNA3,EGFR,GAD2,ERAP1,DISC1,GLYR1,MSL3,PRUNE2,ELOVL5,KCNJ5,MIA2,SCAMP5,NDP,CNOT4,NUMA1,PDGFRA,CAMKV,RETREG1,POLG,FSD1,LRRN3,PRKAR1B,PTN,STUM,SLC9A5,ZNF667,IFT122,ZHX3,NSD1,CRTC1,OSBP2,VIPR2,XRCC4,UPF3A,KCNAB1,AAAS" Drug 6306_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ACTN2,NME5,PLA2G6,ALK,ASTN1,SLC4A4,ATP6V0A1,CFLAR,CFAP410,CBS,ARHGEF1,DLGAP1,HOMER3,IQCK,WHRN,DUSP9,HIPK3,EFNA3,MBNL2,PLXNC1,LPAR6,EIF4G2,DMTN,FGFR1,BAIAP2,HPCAL4,IQCG,TRMO,ZNF276,POLL,GNAO1,GNG3,GPD2,SPACA9,PTPRT,NXPH3,SCRG1,ITGA7,KCNF1,NF1,CNOT4,SNTG1,STRN3,PROX1,KIRREL1,PEX26,TMCC1,ZHX3,PHLDB1,DNAH7,TK2,TLR4,LMF1,ZNF74,KCNAB1,UBE3B" Drug 5055_DN Norethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "APBB2,APOC1,PPFIA3,CDC14B,MARK4,ALDH4A1,SLC4A4,BTRC,HIP1R,CDC42,EPS15L1,RAB28,HAPLN1,CSF1R,GPRASP1,DNM2,ATN1,DTNA,HIPK3,MBNL2,EN2,PLEKHO1,DMTN,STX2,ERBB2,CAMKK2,SESN1,C1QL1,GLRB,RNFT2,BACH2,HSF2,KPNA5,MAPT,ZNF862,CNOT4,PC,SNX10,FA2H,MAPK7,RAP1GAP,BSDC1,SCN8A,DZIP1,WDR37,LIMS2,WDTC1,SPTAN1,ELOVL4,ASTN2,TRIO,UGT8,VIPR2,NDRG4,SPHK2,HPS4" Drug 3755_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADORA3,APAF1,AQP4,CDK10,PPP4R4,RASL11B,CADM3,KIF1A,BAIAP3,SYNGR3,CD38,DCLK1,RAB26,FEZ1,NOS1AP,RIPOR2,SV2A,ECM2,EFNB3,NCALD,REEP2,PTK2B,CAMSAP1,GABRA2,GABRA5,GATM,ALDH1L1,RUNDC3A,GNG4,KCNB1,KCNN1,LMO1,VWA5A,MATN3,MOBP,MSI1,MYH7,PBX1,GPR85,PGAM2,MAPK10,PTH1R,PTPRG,PTPRH,PTPRN2,KCTD17,HUNK,MYH15,SPTB,NPAS3,LMO3,VAMP1,TCF7,PIK3R5,SEZ6L,KCNAB1" Drug 2111_UP Methocarbamol [532-03-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AK2,APBB1,KCNAB2,APOC1,CDK13,PDE8B,BCHE,SYNJ2,HAP1,SCARB1,ARHGAP33,ARHGAP22,HOMER3,COL9A2,CREB5,SNPH,DBT,SMG7,AK5,HIPK3,CELSR3,MBNL2,ETV1,B4GALNT1,SYT17,C1QL1,GPR37,KIF3A,KCNN1,GIT1,NDUFA5,NOS1,CNOT4,NTRK2,PAK3,PDE2A,MED1,CNTLN,RGS10,TRAPPC13,SCN8A,FNDC3A,URGCP,PEX26,ZKSCAN3,TNIK,DDN,TROVE2,VAMP1,ASTN2,SMG6,TCF4,SYNE1,TRPC1,NT5M,PARP6" Drug 5868_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ALAD,DDO,ARRB2,SLC4A4,CFLAR,ST3GAL5,MYRF,CACNA1A,SCARB1,PLEKHB1,CRY2,GPRASP1,RABGAP1L,EDN1,HIPK3,SEMA3D,CELSR3,ELAVL3,EFS,ETV1,ZNF589,FER,OLFM1,ANKFY1,SORBS1,PDLIM5,B3GAT1,FYB1,GAP43,SPACA9,GRIK5,GRM1,DHX35,IGF1,ITGA7,KCNF1,KCNJ5,KHK,KPNA5,CNOT4,NPY,ZSCAN2,RGS7,RGS10,TRAPPC13,MAPK12,SLC8A1,ELMO2,SNCA,PDZRN3,WDTC1,VAV1,WIPF1,SLC17A7,UBE3B,GAN" Drug 1512_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RALGAPA1,ASIC1,LTBP4,APBA2,PPP4R4,SYNJ1,ST3GAL5,CAMK2B,RUNX1T1,ARHGEF2,ARHGAP33,CHRNB2,TAOK2,FADS2,QKI,WHRN,CSF1R,SDC3,GREB1,BRINP1,ST8SIA3,EFNB3,MBNL2,C3orf18,FHL1,FOXF2,HPGDS,MSL3,GPM6B,IL6ST,ITGAM,MAP4,MMP16,MOBP,NPR2,NPTX2,PAX6,PCDH9,CDK18,PDE4A,PNMA3,SEPT4,MINDY2,PRPH,RAD52,STUM,BTBD7,SLN,WDTC1,STX1A,DOCK9,TGFBR3,TK2,TNS1,TRIO,KAT6A" Drug 6467_UP Altretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "KIDINS220,ASCL1,BRINP2,N4BP2L1,BTRC,ARHGEF2,CLGN,FADS2,WHRN,SLC4A7,CSF1,DCAF4,DBT,ST8SIA3,SGK2,EFNB3,RGS17,VPS13B,CORO2B,DLC1,ANKFY1,B3GAT1,GABRA5,TMEM8B,SRCAP,GNAO1,GPD2,GRM8,PTGDR2,KLF12,KCNMA1,KIF5A,KIT,MAN2A2,SLCO1C1,NUMA1,OPCML,CLDN11,PDE3B,CAMKV,SLC25A23,SLC6A15,RGS12,RPS6KA2,SNCA,ZCCHC24,ZHX3,WSCD1,TRIM2,ARHGEF12,AP4E1,WIPF1,NSD2,SLC30A3,SCG2,ADAMTSL3" Drug 3972_UP Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ASIC2,C1QTNF1,BIN1,GYG2,CACNB2,SEPT7,RAB33A,STOML1,CABP1,CRY2,VCAN,ARHGEF4,AK5,CHRDL1,ST8SIA3,SNX29,EDNRA,HSD17B14,EN2,EPHB1,ERCC2,PTK2B,DLC1,TBR1,GABRG2,LYVE1,GLRB,STMN2,SOX21,NXPH3,KLF12,IL11RA,ITGAM,KCNJ5,AFDN,PAH,CAMKV,PLCB2,EPN1,POU3F4,PTAFR,ZFHX4,SYNDIG1,ST6GAL1,SLC11A1,SLCO1A2,CXXC4,COLGALT2,MAPK8IP3,ATP11A,ADGRL3,TCF4,PCDHGB6,PIK3R5,UCHL1,NLRP3" Drug 5243_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "DPF1,SYN3,KIDINS220,APBB2,EPB41L5,GAS7,FAM131A,CDK13,SLC4A4,BCL2L2,CACNG1,SLC16A4,CDO1,VAX2,FHL5,CRY2,SDC3,ARHGAP24,RIMS3,PARD6A,TMCC2,DMPK,PLXNC1,FLNC,FYN,HBS1L,GCNT2,RUNDC3A,GPM6B,GPR37,BTN2A1,HLF,IRF8,ITIH2,KIF5A,LSS,MID1,PLCD1,EPN1,PPARA,CCDC40,ENOX1,SBF1,NLGN1,KANSL3,ARHGEF40,IZUMO4,ARHGAP26,RBM26,VAMP1,SYN2,PIK3R5,MICAL1,XRCC4,SPHK2,ITM2C" Drug 5832_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "PLA2G6,ADGRF5,ALK,BIN1,APBB2,SEMA4G,PPP4R4,ATP2B3,CFLAR,ST3GAL5,HAP1,NEURL1,B4GALT6,TENM4,PHF14,KIAA0513,GIT2,IRAK4,NRN1,FGFR1,BAIAP2,PNMA2,ZMYND11,SRCAP,GNAO1,PRUNE2,TDRKH,GPR17,KLF12,TJAP1,IL11RA,KCNF1,MX1,NEFM,NPTX1,ODF2,PIK3R1,PTPA,MAPK10,ATG16L1,MYH14,AMBRA1,SLC9A5,TMCC1,KDM4C,TROVE2,NXT2,CEP68,ASTN2,TRIM2,DOCK9,TPD52,TPM2,WIPF1,PHTF2,RNF146" Drug 3337_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ASIC1,ARID1A,NDRG2,C1QTNF1,ALCAM,BIN1,ANK1,LDLRAD4,CFAP410,RHBDL1,CCKBR,CHN2,SLC24A2,NECTIN3,ENTPD4,CNTNAP2,RIMS3,CTIF,DMPK,EDN3,MBNL2,TNK2,VPS13B,KIAA1109,FHL1,AGAP2,GLS,GPD2,LPAR4,GPER1,GRIK5,NR3C1,PTGDR2,VSIG4,LAMA2,MOBP,MX1,TNPO2,POU6F1,MED1,ZSCAN32,CCDC40,TRIM68,KCNIP1,RASA3,PEX26,SLC11A1,SNCA,ATP11A,TRIM2,OBSL1,HEY2,CABIN1,TRIO,WNK1,NT5M" Drug 4661_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ASPHD1,AMPH,KCNAB2,APC,ST3GAL5,GYG2,CACNA1I,CFAP410,KIAA1549L,NRXN2,TPP1,STOML1,RAB26,HOMER3,AKAP5,CHD5,PDE4DIP,TOX,C2CD2L,ARNT2,DPH1,TOM1,EGFR,EZH1,ABCA8,ZNF589,B3GAT1,GATM,LYVE1,GPD1,STMN2,RAPGEF1,ATXN2L,HLF,ADAM22,LYRM9,CNOT4,P2RX7,PDGFRA,RETREG1,MAPK8,PLPPR1,RAD51D,ENOX1,KCTD17,SCNN1D,SORCS3,KIF21B,DOK5,ATP11A,EXOC7,SMG6,CDK20,TPM3,TRO,JPH3" Drug 3130_DN Halofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AMPD3,BIN1,ANK3,APAF1,APBB2,APC,APOC1,PDE8B,KIF1A,LDLRAD4,CHN2,JAM2,IQCK,CSNK1E,SIPA1L1,DLC1,KIAA1109,CAMSAP1,FHL1,CSPG5,GAA,ZNF44,ELOVL5,IL6ST,KIT,LAMA2,MAP4,MIA2,AFDN,GIT1,ZNF862,NDUFA5,SLC11A2,NUCB1,OLR1,PDPK1,PLCL1,SLC25A23,PPARA,MAPK8,RAD52,BEND5,MYH14,MRAS,CPEB3,CDK19,NCDN,TCF7,PCDHGA10,SYNE1,TEX15,PARD3,BEST1,NPDC1,ATP6V0E2,TIGD6" Drug 6570_DN Gly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "C1QTNF3,APBB2,APOC1,CDK10,SEMA4G,ASPH,ALDH4A1,MTMR9,LDLRAD4,CFAP410,CDC42,LRRFIP1,CSF1,SLITRK5,GREB1,ARHGEF4,SPOCK2,G3BP2,DTNA,STX2,SPEG,FGFR1,BAIAP2,SEMA4D,FLT1,CINP,GCNT2,COPS8,POLL,ELOVL5,SHISAL1,KCND3,MAPT,NDP,RAB3A,RNASEL,SH3BP2,CNKSR2,SLC1A7,SIRT2,KBTBD4,BTBD7,SPTAN1,PBLD,FCHO1,SYT11,COBL,WWC1,ARHGEF12,TK2,ZKSCAN5,RPRM,XRCC4,ZNF225,MAP3K12,KCNAB1" Drug 2537_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADCY6,NR0B1,ALK,ANK1,DDO,PDE8B,ASPH,ALDH4A1,CCDC181,B3GALT2,HAP1,EPS15L1,STOML1,CRMP1,CRY2,SEC14L5,KIAA0513,ZNF337,DGKG,GSDME,TMCC2,E2F5,CNNM1,EFNB3,KIAA1109,FLT1,SORBS1,GFER,GLI2,GNAO1,IL1RAPL1,KLF12,KCNJ3,MYO6,NCAM1,NPR2,P2RY1,KCNK10,POU3F2,PPP1R1A,PROX1,RAB3IL1,SUGCT,EMID1,SEMA6D,ZNF821,ABLIM3,FAIM2,SPTB,SYT1,WSCD1,TCF7L2,CRTC1,AP4E1,TRPS1,SLC17A7" Drug 2150_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "C3orf14,APAF1,APBB2,APOC1,ARRB1,ZBTB10,BCL2L2,SYNJ2,THSD7A,CLCN4,DNAJB5,CREM,ABCG1,MFAP3L,TRAPPC9,DTNA,CNNM1,EFNB3,FAM13A,VPS13B,DLC1,FGFR1,CAMSAP1,FOXG1,GALC,ALDH1L1,GJB1,ZNF276,GPR19,ITIH2,KCNMA1,MAP4,MDM4,MIA2,ZNF862,NEK1,NUMA1,PDE4B,CEP41,RIPOR1,RAB3A,ZNF493,FBXW7,MAP6D1,HSPA4L,SHANK2,SEPT8,CEP68,FAM168A,CAMSAP2,WWC1,TBCEL,KAT6B,RUNDC3B,NT5M,EVI5" Drug 4492_UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "NDRG2,C1QTNF3,APAF1,BCAS1,CDK13,ATM,ATP1A3,CFLAR,FUBP1,NEURL1,ZFYVE9,STOML1,DNAJB5,QKI,CNTN1,WHRN,COL9A3,CPS1,NCOR2,CSF1,MICAL2,PLCH2,CTH,EXOG,DSCAM,DTNA,EDNRB,MBNL2,STX2,REEP2,FGFR1,FAM49B,OGA,RND1,ITIH2,JAK2,LAMA2,AFDN,MMP17,ADAM22,NF1,NTRK2,PDE4A,STRN3,MINDY2,PPP2R2B,PROX1,ZSCAN2,RBM34,DOK5,SP4,ARHGAP26,TRIO,TRO,VAV1,EVI5" Drug 2326_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "SYN3,ACTN2,NME5,SPARCL1,KCNAB2,APC,SEMA4G,ARHGDIG,CADM3,CACNA1D,CACNB2,USP2,ARHGAP33,CHRNB2,FADS2,CNTFR,RCHY1,CSF1,LRIG1,RASSF2,ARMCX2,DRD1,DSCAM,REEP2,ATP8A1,FCGRT,FGF1,OLFM1,FGR,FOLR2,DISC1,SRCAP,GLI2,KCNN1,KITLG,MMP16,MOBP,ADAM22,SLCO1C1,PDE4A,PLCD1,PLTP,C19orf57,PPARA,MINDY2,MAPK10,PRODH,PTAFR,STUM,LIMCH1,ARC,GPR161,FAM155A,WIPF1,LAT2,SENP7" Drug 2536_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AP2A2,NR0B1,PLA2G6,CDC42BPA,ASPH,ALDH4A1,SLC4A4,THSD7A,CHN2,COL9A2,CRMP1,CRY2,CTNND2,DCAF4,SEC14L5,SNPH,DGKG,TMCC2,TRAPPC9,EDNRB,CNNM1,ELAVL3,C3orf18,HSD17B14,ERBB2,TLR7,CORO2B,KIAA1109,ARPP21,ZNF276,RAB30,SCIN,KCND3,KIFC3,MEF2C,MMP16,MYCN,NUMA1,PDE4D,PFKFB4,PGAM2,EPN1,MAPK10,RIPOR1,CCDC40,ZMAT4,SMTN,SLCO1A2,KDM4B,HECW1,SPTAN1,TROVE2,MCF2L,AMOT,VAV2,ZNF74" Drug 3784_DN Vincamine [1617-90-9]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ARID1A,NME5,PLA2G6,LTBP4,APBB1,BCHE,BMP7,CACNG1,CBS,SCARB1,CDC42,CDH10,LRRFIP1,CHM,PLEKHB1,NRXN3,ZFYVE9,ABCG2,IFFO1,RABGAP1L,EIF4G2,TUBD1,ETV1,F5,FGF1,OGA,DISC1,GFER,POLL,PTGDR2,KCNB1,LSS,NF1,NFYA,NPR2,PCBP3,PDE4D,SERPINI1,SYTL2,FAM120C,ZSCAN2,ACSS3,SUSD4,RGS4,NTNG1,FNDC3A,OGDHL,WDTC1,SOX15,SP4,THSD1,TRIM2,TMOD1,CABIN1,SCG2,SENP7" Drug 3219_DN Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RGS20,MARK4,ALDH4A1,CACNA1D,HOMER3,ARMC8,MICAL2,SDC3,DCAF8,EDNRA,EML1,DMTN,ANKMY1,EZH1,KAT8,BAIAP2,FHL1,MPP6,GABRA2,POLL,RNFT2,HSF2,KIF2A,LIG4,GIT1,ADAM22,NAP1L2,NFYA,CNOT4,PCDH9,PLEC,RALGDS,ROBO1,NEK11,MCMBP,AMBRA1,KBTBD4,ELMO2,BTBD7,COA1,CDK5RAP2,KDM4B,KDM4C,TROVE2,CEP68,STX1A,PLCB1,MTCL1,KAT6B,RBFOX2,HIRA,PLPPR2,VAV1,SEMA3B,MPPE1,SMIM8" Drug 1818_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "MTUS1,ANK3,APBB1,APP,ARNTL,RCBTB2,QKI,SLC4A7,SMARCAL1,DAPK3,RUSC2,RABGAP1L,KBTBD11,TOM1,EDN1,IRAK4,ACSL4,SCARA3,GBX2,SRCAP,HTATSF1,GUCY1A1,DHX35,IFI16,SHISAL1,IL6ST,GIT1,MX1,ZNF862,NACA,NAP1L1,NPR2,GPSM2,MBOAT7,POLG,SNRK,RBBP6,DPF2,MRPS18A,FUZ,SLC1A3,ST5,MAPK8IP3,IQCE,EHBP1,TCF7L2,KCTD2,EIF4ENIF1,CLIP2,XRCC4,MAP3K12,HPS4,NAV3,NAV2,UBE3B,SMIM8" Drug 2644_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADRA1D,KIDINS220,MRTFA,BIN1,APC,FAM131A,MARK4,SYNJ1,SGCE,CACNA1G,NEURL1,CHRNA4,DNAJB5,COL9A3,ARHGEF10,SPOCK2,RABGAP1L,TMCC2,ATN1,TNK2,DMTN,RASGRP2,SPEG,KIAA1109,FGR,ALDH1L1,C1QL1,GNAS,TDRKH,INPP5B,JAK2,KCNK2,KCNQ3,VWA5A,MEF2C,NPTX1,RETREG1,PLP1,PTPRH,RAD52,FAM184A,BEND5,FRMPD1,SLC11A1,LIMCH1,KDM4C,IQSEC2,SS18,VAMP1,SYT5,ROBO3,HIRA,FAM155A,ZFP37,GDPD5,SENP7" Drug 3987_DN "Azathymine, 6 [932-53-6]; Down 200; 31.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADRA1D,MTUS1,MRTFA,APP,DNAH17,ASPH,KIF1A,DNAJB5,RAB26,HOMER3,WHRN,CREM,HAPLN1,HINFP,ARHGEF10,CSNK1E,PARD6A,DLG3,CDON,ATN1,SIDT2,MBNL2,AASS,IRAK4,MRNIP,MTSS1L,FAM49B,SYT17,TDRKH,GRM8,GUCY1A2,MAPT,MEF2C,TAGLN3,NDUFA5,NUMA1,ODF2,GRAMD1C,FAM120C,PAQR6,FRMPD1,ASAP3,SLC1A7,PEX26,SLC6A9,TSNAXIP1,ARHGAP26,MAPK8IP3,ELOVL4,ATP11A,TIAM1,TRIO,OSBP2,KCNAB1,NUP214,TIGD6" Drug 5409_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "DPF1,ARID1A,NDRG2,ALCAM,AMPD3,GAS7,CDK13,ASPH,N4BP2L1,NRP2,CALB2,CAMK2G,KRIT1,ARHGEF1,VAX2,CNTN1,AKAP7,SLC4A7,ABCG1,DCAF4,GSDME,EDNRB,TENM1,COQ7,DMTN,DLC1,HPCAL4,GLS,POLL,GNG3,GPM6B,CNTRL,GRM3,RASSF8,JAK2,KCNH2,KCNN1,LIG4,MAP2,MAPT,MPP2,MSR1,PLCD1,CEP41,MAPK10,PTHLH,ZNF493,DOCK10,FBXO11,SMTN,VAMP1,PLCB1,DMXL2,PCDHGA10,SYNC,MARCH8" Drug 4703_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "KLRC4,NME5,LTBP4,ANK3,ARSE,CDK13,BRINP2,SLC4A4,AZGP1,CA4,SCARB1,SOCS6,CHRNA4,TPP1,FAM149A,IFFO1,CREM,EDRF1,SEC14L5,DCT,EFS,AFF2,SORBS1,CAMKK2,OGA,GALC,SIGLEC8,RUNDC3A,MSL3,GRM1,GRM7,HPSE2,KCNA2,KITLG,AFF1,AFDN,NELL2,NF1,PDE1C,PDE4B,PLCD1,ZSCAN32,RAB3IL1,KHDRBS2,TTLL7,FRMPD1,SLC11A1,LIMCH1,NPAS3,SPART,MAPK8IP3,PHLDB1,CHST5,ZNF74,PRDM10,ITM2C" Drug 5818_UP Hecogenin [467-55-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "RBM10,BRAP,APBB2,APC,LGR5,AQP4,SEMA4G,ARHGDIG,MARK4,SLC4A4,CALB2,HAP1,CDC42,CNOT8,VCAN,DCAF8,BRINP1,GIT2,ARMCX2,MYEF2,C2CD2L,ATN1,SCML2,ZNF589,DENND2A,SEPT9,GNAS,GRIK5,GRM8,AP4S1,KIF5C,MAPT,MOBP,TAGLN3,CNOT4,NTRK2,NUCB1,BCAS3,PTPN13,PTPRN2,RAB3IL1,PID1,TCP11L1,KCNIP1,FNDC3A,OGDHL,KDM4B,IQSEC2,COLGALT2,IQCE,TRIM2,TMOD1,RIMBP2,VGF,TFIP11,RNF170" Drug 4228_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "TKTL1,ACTN2,NDRG2,ADORA1,AP2A2,PKP4,APAF1,KCNAB2,PPP4R4,NCOA1,SLC2A11,BMP7,BAIAP3,KRIT1,FOXN3,ASIC3,CNTFR,CRY2,CSF1,FEZ1,MAML1,MFAP3L,SPOCK3,DTNA,ABCC9,ETV1,FGF1,CAMSAP1,DCTN2,NSG1,GPM6B,STON1,GRM7,GSTM5,IFI16,VWA5A,MARK1,NOS1,NTRK3,PCDH9,PDE4D,SERPINI1,C1orf54,GAL3ST4,MYH14,PKNOX2,LIMCH1,FAM168A,TCF7,ZFPM2,GPR161,TMOD1,TRPC1,ZNF225,KCNAB1,MVB12B" Drug 4158_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "SEMA6A,APBA2,APBB2,APC,ATP1A2,SLC2A11,KSR1,CACNA2D1,CALB1,CAST,RUNX1T1,USP2,KCNAB3,ADGRG1,SULT4A1,NOS1AP,ARHGAP24,DCT,ELMO1,C2CD2L,FOXG1,ZNF44,ALDH1L1,SRCAP,GRM7,GRM8,HLF,IL6ST,KIF5C,MAOB,NEFM,NTRK2,KCNK10,PURG,PTAFR,ELOVL2,PTPRB,ZMAT4,RGS12,KLHDC8A,CARF,SEMA6D,PKNOX2,RIMS1,SNAP25,PDZD2,ATP10B,PCDHGB6,PCDHA5,LILRA4,TTPA,UGT8,WIPF1,XRCC4,NT5M,EVI5" Drug 7273_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "KIDINS220,MTUS1,PPFIA1,APOC1,APP,PPP4R4,CDK13,NRP2,MAP7,KRIT1,SCARB1,RAB28,NRXN3,CLCN4,QKI,ARMC8,MICAL2,VCAN,CNTNAP2,DZIP3,HDAC9,DBT,RUSC2,SMG7,DYNC1I1,DTNA,CNNM1,FAM13A,PLXNC1,CDKL3,F3,ST3GAL6,KIAA1109,GLYR1,DIPK1A,MDFI,NFYA,OPRL1,PALM,PTX3,TTLL7,NCBP3,ITSN1,PPP4R3A,SLC20A2,KDM4B,TAB2,DIP2A,WWC1,FBXW11,ZEB1,TK2,RUNDC3B,ZNF711,NAV3,PHTF2" Drug 2460_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "NDRG3,BEGAIN,APBB2,RASL11B,KIF1A,BMP7,FUBP1,MAP7,USP2,ZFYVE9,HOMER3,CSF1,PHF14,CTNND1,TBC1D5,DSCAM,E2F5,EFNA3,MRNIP,EIF1,CEND1,PTK2B,KAT8,KIAA1109,ANKFY1,TRAF3IP2,INPP5K,GART,HSF2,IL6R,KCNJ5,NF1,ODF2,OPRL1,CCSER2,EPN1,ZNF426,PPARA,FAM184A,ZFHX4,SLC1A3,CXXC4,ZNF667,ATP10B,SS18,NXT2,KANK1,DNMBP,AP4E1,RBFOX2,TPM1,TPM3,SSBP2,NSD2,ZNF24,SYNC" Drug 5482_DN Diprophylline [479-18-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "CDC42BPA,APP,SCAPER,SPAG9,CRLF1,CLU,SOCS5,PDE4DIP,G3BP2,DLG3,FEM1B,IRAK4,F3,BAIAP2,POLL,KLF12,MAP4,MIA2,MPP2,ZNF862,NF1,NFYA,NRGN,PDE3B,PDE4A,PDE4B,CCSER2,SMIM7,PRODH,RNH1,MYH14,GSTCD,SAFB,ZNF821,CDK5RAP2,MAPKBP1,EMC1,KDM4C,CDK19,ELOVL4,STX1A,POPDC3,IQCE,ZNF34,TIAM1,KCTD2,TNNT1,CABIN1,CADM1,RPRM,UBTF,PLPPR2,KLC2,ZNF74,ZFAND5,HPS4" Drug 2229_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "AP2A2,MRTFA,AMH,ATP1A2,SLC4A4,N4BP2L1,TPP1,STOML1,FAM149A,MYRIP,MICAL2,TOX,DRD1,ABCC9,MTSS1L,EPHB1,NCALD,IGSF6,ST3GAL6,FGF13,FHL1,DCTN2,CAMKK2,PRUNE2,GPM6A,GRIK2,GRM7,PTGDR2,HLF,KIF5A,SMAD1,MDFI,PCBP3,PDE4B,PPP2R2B,GRAMD1C,PTAFR,FAM120C,CRTAC1,RGS12,KLHDC8A,TMEM206,FRMPD1,ASAP3,BCAN,SLC14A1,LIMCH1,FAIM2,SOX2,SPTB,SMG6,PCDHA5,GPR161,TRO,AMOT,KCNK12" Drug 3975_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "SYN3,BEGAIN,TRMT9B,BIN1,APBA2,APLP1,APOC1,CDK13,ASCL1,RGS9,KSR1,CACNA1I,CAMK2B,NEURL1,CDH2,WHRN,MICAL2,PHYHIP,SRGAP3,NTM,TRAPPC9,ST8SIA3,EGR3,ZNF391,ANKMY1,REEP2,CORO2B,FGFR1,FHL1,GAP43,ALDH1L1,LYVE1,HPGDS,GRK4,GRM8,AP4S1,TJAP1,KCNN1,L1CAM,ADAM22,MYT1,OMG,KCNK10,PALM,PLP1,SAMD9,C1orf54,RFX3,SMPD3,MRAS,CDK19,AJAP1,WSCD1,VAV2,LAT2,TIGD6" Drug 3128_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ADORA1,KIDINS220,AGT,OSBPL1A,BEGAIN,ANK3,CDC14B,ALDH4A1,CACNA1I,CACNB4,CAPN3,SLC16A4,EPS15L1,BRINP1,DTNA,ING4,STX2,RRAGB,KAT8,FGFR1,FYB1,GAD2,ALDH1L1,SRCAP,ZNF276,PCLO,GUCY1A2,GUCY1B1,PADI2,ICA1,KCND3,MAP4,MDFI,PLCL1,PMS2,FSD1,PKIA,RELN,ZSCAN32,FAM120C,ATG16L1,KCTD17,PNMA8A,MAP6D1,MRAS,BTBD7,ZNF667,KDM4B,SPART,TROVE2,WWC1,OBSL1,TRPS1,FLRT2,TFIP11,PCBP4" Drug 4620_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "MTUS1,C1QTNF1,MRTFA,TRMT9B,PDE8B,ASTN1,ATP2B2,CADM3,ADGRB2,BAIAP3,CFAP410,CDH10,PLEKHB1,ABCG2,DNAJB5,ARMC8,KIAA0513,BRINP1,MFAP3L,DTNB,TOM1,HEYL,PLXNC1,AASS,ING4,MTSS1L,FGFR3,DENND2A,SIGLEC8,GCNT2,GFER,LYVE1,MSL3,CACFD1,MAP4K5,LIG4,MX1,NEUROD1,CNOT4,OPCML,PAK3,ELOVL2,PTPRB,RAD52,MYH14,ASAP3,SLN,VAMP1,SMG6,AHCYL2,THRA,TK2,TPM2,ZMYND8,CADM1,EVI5" Drug 7484_DN Ajmaline [4360-12-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "NDRG3,ADCY6,OSBPL1A,AK2,PLA2G6,AMT,APLP1,DGKD,MARCH3,ASPH,SCAPER,TAOK2,AKAP7,GREB1,EDRF1,DCAF8,HDAC4,ZNF337,JAKMIP2,HIPK3,SIDT2,EIF5,LRRC23,SCML2,KIAA1109,PRKAG2,GALC,ALDH1L1,MALT1,CNTRL,NR3C1,IDH3B,KHK,LIG4,GIT1,PBX1,PDE3B,PTPA,PPP3CC,ACSS3,FAM184A,ZCWPW1,GTDC1,RGS10,RGS12,SH3BP2,FERMT1,LIMS2,BTBD7,SLC20A2,TBL1X,KCTD2,TRPC1,PLPPR2,VIPR2,KCNAB1" Drug 1897_UP Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ACTN2,APBB2,PPFIA3,SEMA4G,MARK4,INA,CLCN3,NRXN1,AKAP7,BAG4,CDC42BPB,CREM,SOCS5,DAPK3,BRINP1,C2CD2L,SMG7,ING4,C3orf18,F3,ZNF589,OLFM1,PDLIM5,NCKAP1,GLYR1,HTATSF1,SLC2A6,KLF12,SHISAL1,IL6R,IL6ST,KTN1,MAP4,N6AMT1,NCAM1,PAK3,GPSM2,ZSCAN32,C1orf109,STUM,SH3GL2,KIF16B,CDK5RAP2,TNIK,IQSEC2,DIP2A,GSE1,TCF7L2,AHCYL2,CBX5,TMOD1,ZMYND8,TSC2,UCHL1,LMF1,MAP3K12" Drug 3859_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "NDRG2,APAF1,APLP1,RGS20,SLC2A11,BACH1,LDLRAD4,CAMK2B,SLC16A4,CDO1,CLGN,ADGRG1,PICK1,CNTN1,VCAN,DAPK3,G3BP2,TMCC2,DNAH9,DTNA,DYRK1A,FRY,ING4,EPB41,ERCC2,CEND1,KIAA1109,FGF13,C1orf61,CAMKK2,KHDRBS3,C1QL1,ITGAM,KCNMA1,KCNN1,KIT,IPO5,TM6SF1,KITLG,MMP16,OMG,PDE3B,PTAFR,PNMA8A,ASAP3,KANSL3,RBM34,INKA2,ARC,POPDC3,SMG6,SLC44A1,TIAM1,TIMP4,XRCC4,PRDM10" Drug 6030_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "PPFIA3,ASPH,ZBTB10,CFLAR,SYNJ2,KRIT1,SLIT2,RAB28,NMT2,QKI,COL4A5,SLC4A7,CREM,FEZ1,PDE4DIP,FAM169A,GIT2,FBXL5,GNE,DTNA,EDNRA,EFNA3,ING4,STX2,KAT8,BAIAP2,COPS8,HTATSF1,NR3C1,HNMT,KCNJ3,SERPINE2,PRODH,SIDT1,RAB3A,ZDHHC14,FOXRED2,ZNF821,ITSN1,FBXO11,SLC20A2,SLC22A4,SPATA7,KIAA0930,TRIM2,CHST8,TIAM1,TMOD1,PARD3,TPD52,TRIO,REEP1,WNK1,EVI5,HPS4,MPPE1" Drug 7319_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ABHD6,ALAD,BIN1,APLP1,APOC1,PPFIA3,ALDH4A1,BID,ARHGEF7,NFS1,SCARB1,CHN2,CSNK1E,USP6NL,ARHGAP24,KLHL3,FEM1B,EFNA3,EGFR,LRRC23,ERCC2,VPS26C,TMEM8B,GCNT2,GPD2,GPM6B,CNTRL,HNMT,KIF2A,KIF5C,NF1,PBX1,FSD1,PPP5C,GON4L,ELOVL2,RAD51D,RPS6KA2,ATXN2,OGDHL,CDK5RAP2,ZBTB43,SRPK2,ARHGEF9,VPS13A,ARHGEF12,R3HDM1,RBFOX2,TRPC1,SSBP2,ZKSCAN5,NSD2,ZBTB14,TFIP11,WNK1,HPS4" Drug 3519_UP Etomidate [33125-97-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ACTN2,NME5,ALK,SEMA7A,APBA2,DDO,ATP2A2,ADGRB1,CACNB2,ARHGEF2,FOXN3,TAOK2,CNN3,CABP1,COL9A3,CPS1,NCOR2,PHF14,DOCK4,RASSF2,CNIH3,TMCC2,DSCAM,C3orf18,ETV1,ANKMY1,CEND1,FAM198B,DKK3,ERAP1,GNAS,GRM8,ICA1,KCNMA1,NEUROD1,GPR85,POU3F2,PPP5C,SAMD9,RAB3A,RAB3IL1,ZFP2,FRMPD1,SMARCD3,ATP10B,INKA2,MAPK8IP3,SYT5,TBCEL,PCDHGA10,PCDHGA1,TNS2,CRTC1,TF,TRPC1,KCNAB1" Drug 2226_DN Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "KIDINS220,C1QTNF3,APBA2,KCNAB2,RGS20,PLA2G4C,SYNJ2,GYG2,SLIT2,DNAJB5,PICK1,ABCG1,CSF1R,PPP6R2,SEC14L5,SMG7,TMCC2,CDON,SIDT2,SORBS3,EZH1,FHL1,FAM49B,DISC1,SEPT9,SRCAP,SPACA9,GRIK5,ARHGAP19,MATK,MEIS2,MMP16,NF1,NRGN,PDE3B,PIK3CD,PPP2R2B,LRRC49,RAB3IL1,ZCWPW1,RGS10,SUPT20H,PREX2,DOK5,ZHX3,ARC,MTCL1,TBL1X,ZKSCAN5,FAM155A,FLRT2,PLPPR2,GDPD5,HPS4,KCNAB1,KAT6A" Drug 3092_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "TKTL1,ADD2,ADORA1,BCAR3,AMPH,CASK,ARSE,PDE8B,ADAM23,CACNA1I,HIP1R,NEURL1,ZFYVE9,CNTN1,CREM,SH2B1,ABCG1,DLG4,ATN1,FHL1,GAD1,HPGDS,POLL,GNG4,GRM7,GSTM5,ELOVL5,HNMT,MAP4,MYO6,OMG,PCDH9,PDE1C,POU3F2,POU3F4,SYTL2,TMEM104,RGS12,SYNDIG1,ST6GAL1,SMTN,PKNOX2,SLN,PDZRN3,TNIK,DOK5,DDN,SSTR2,RPGRIP1L,ZFPM2,TJP1,TK2,TMOD1,TNS1,VAV2,NT5M" Drug 6763_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.89E-06 2.40E-01 9.24E-05 1.05E-03 56 198 "ASPHD1,PKP4,SLC4A4,CFAP410,CACNA2D1,SCARB1,SYNGR3,LARGE1,CNTFR,DAPK3,MFAP3L,SMG7,DTNA,DUSP9,TENM1,RASL12,DLC1,FGF1,C1orf61,DCTN2,B3GAT1,ALDH1L1,GRIK5,MAN2A2,ADAM11,MDFI,TM6SF1,MOBP,P2RY13,NNAT,NPPA,PDE4D,RETREG1,PTCH1,PTPRH,TMEM231,C1orf54,GAL3ST4,RET,RGS12,IL17RB,FBXO11,KDM4B,BEX1,ATP10B,SSTR2,MAPK8IP3,COBL,DOCK9,TK2,CABIN1,HIRA,EMSY,KCNAB1,PARP11,EPM2A" Drug CID000002548 AC1L1DXE Stitch 4.91E-06 2.41E-01 9.27E-05 1.05E-03 77 299 "KCNH8,ACHE,ADORA1,ANK1,ANK2,ANK3,APP,BBS2,BCHE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,CCKBR,CACNA2D2,CHGA,ASIC3,CHRM1,CNR1,DMPK,EDN1,CACNG7,CACNG2,ACTL6B,FOLH1,B3GAT1,ATP8A2,GFAP,CRCP,GRIK1,GRIK3,GRIK4,GRIN2C,GRIN2D,HRH3,TNFAIP8L3,IGFBP1,LIMS1,NOS1,NPY,OPRL1,PDYN,PENK,PIK3C2A,PIK3CD,PIK3R1,PKD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK8,MAPK9,MAPK10,PYGM,RYR1,RYR3,SCNN1D,CLSTN2,SST,TAC1,TAC3,TACR1,MLST8,WDR7,ACTR6,PIK3R5,UCHL1,SCG2" Drug ctd:D008559 Memantine CTD 4.95E-06 2.42E-01 9.33E-05 1.06E-03 10 14 "ACHE,APP,CAMK2A,DLGAP2,DLG4,GFAP,IL12A,ITGAM,PENK,PRKCG" Drug CID000004795 AC1L1IZ2 Stitch 4.95E-06 2.43E-01 9.34E-05 1.06E-03 78 304 "SYN3,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,AK2,MYH7B,PDXK,ARRB1,KIF1A,CALM1,KRIT1,AIFM1,ENTPD2,LRBA,CLCN4,MYL6B,CPS1,AK5,DNAH9,EGFR,IRAK4,TUBD1,TUBB3,TUBB4A,ACTL6B,TUBA8,GK,TUBA1C,GSN,KIF3A,DDX19B,HSP90AA1,MYLK2,TUBB2B,ITPKA,KCNMA1,KHK,MAT2A,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,P2RY13,PFKFB4,PRKACB,PKIA,MAPK10,PTK2,RAB3A,MYH14,GSTCD,RYR1,RYR3,MAPK12,CASC3,MYO18A,SLCO1A2,WDTC1,KIF1B,SYP,ACTR6,TSC1,TST,TUBB2A,TUBB1,P2RY12,PORCN,ANKS1B,WNK1,SHD,TUBA1A" Drug CID000005291 imatinib Stitch 4.95E-06 2.43E-01 9.34E-05 1.06E-03 103 430 "CLK4,ADD3,BRAP,PCDH10,ALK,CNTNAP1,APLP1,API5,BMPR1B,BTK,JAZF1,CACNA1I,DDR1,NGB,RUNX1T1,AIFM1,ARHGEF2,GPR37L1,ABCG2,CNTFR,CDC42BPB,NCOR1,CSF1,CSF1R,CSF2RA,CSF3R,PDE4DIP,HDAC9,MAML1,GIT2,ABI1,EGFR,SORBS3,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,PTK2B,FER,ACTL6B,FGFR1,FGFR3,FGR,FOXO3,FLT1,FYN,WASF3,MSTN,GFRA1,GFRA2,CIT,PTPRT,HBA1,BACH2,HSP90AA1,IGF1,IL6ST,JAK1,JAK2,KIT,LIFR,MATK,KITLG,MTTP,NELL1,NF1,NODAL,NPY,NTRK2,NTRK3,DDR2,PDGFRA,ABCB1,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,PPP2R5E,MAPK3,MAPK8,MAPK9,MAPK10,LAMA1,PTK2,RAP1GDS1,RET,BAALC,PPM1E,MYO18A,SLA,CDK5RAP2,SMARCE1,TEK,LEFTY2,TIE1,ACTR6,ZFP91,SMUG1,TTPA,TUBB2A,FIP1L1,NUP214" Drug 2507_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.03E-06 2.47E-01 9.48E-05 1.08E-03 51 175 "C1QTNF3,BIN1,ANK1,GAS7,MADD,DNAH17,CADM3,CD86,CD38,CHGA,CHN2,COL9A3,CREM,CRMP1,CSF1R,SIPA1L1,DZIP3,DOCK4,SPOCK2,AASS,KIAA1109,BAIAP2,HPCAL4,SIGLEC8,MSTN,KCNC1,KIT,MDFI,MEF2C,NRCAM,TREM2,PDE4B,PDE4D,CCSER2,MAPK7,BCAS3,SUGCT,TCP11L1,SEMA6D,SEC14L1,SH3BP2,ARHGEF40,SLC11A1,IZUMO4,MAPK8IP3,TACR1,CRTC1,TK2,TRO,ZMYND8,KCNK12" Drug CID000003016 diazepam Stitch 5.16E-06 2.53E-01 9.73E-05 1.11E-03 54 189 "ABAT,ADCY2,ADCY5,ADCY6,ADCY8,SLC12A5,ADORA1,ADORA2A,ADORA3,ALDH7A1,BBS2,BCHE,CACNA2D1,CBR1,CCK,CCKBR,PNKD,DBI,GPHN,STX2,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GLRB,GPT2,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM5,HTR2A,NPY,NPTX1,NPTX2,OPRL1,PTCH1,AP1AR,ASIC4,SLC4A3,ARHGEF9,TAC1,ZEB1,SMUG1" Drug 4126_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ADRA1D,LTBP4,BIN1,APBA2,FAM131A,CDC14B,ALDH4A1,BMP7,CACNA1I,CAMK2G,CLGN,TAOK2,PLAA,STOML1,RIMS3,ING4,EN2,ENO2,DLC1,ATP8A1,IQCG,GAD1,INPP5K,SRCAP,GLS,PCLO,CACFD1,GRM8,IL6ST,INPP5B,IPO5,LSS,KCNK10,NLE1,MAPK8,SAMD9,FAM120C,RAB3A,RGS12,RPS6KA2,ASAP3,ABLIM3,SLC6A8,BTBD7,SNCA,DOK5,POPDC3,ROBO3,IQCE,KIAA0930,TNS2,MICAL1,TFIP11,PHTF2,NUP214" Drug 263_UP clofibrate; Up 200; 150uM; MCF7; HG-U133A Broad Institute CMAP Up 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ARID1A,BRAP,ARNTL,ARSF,ALDH4A1,ATM,ATP6V0A1,BCL7A,SYNJ2,CACNA1I,CFAP410,KALRN,CAMK2A,CHRM4,TAOK2,ATRNL1,DCAF8,DCC,DRP2,ATN1,DYRK1A,EFNB3,TNK2,ENO2,ANKMY1,SEPT9,TXNL4A,GRIN1,GRM3,SOX21,FAM107A,ATXN2L,HLF,IRF8,L1CAM,MX1,NCF2,NEUROD1,NF1,NNAT,NOS1,EPN1,POLG,SH3TC2,EMID1,FNDC3A,SLC11A1,ST5,SEZ6L,FAM155A,PLPPR2,VAV2,LAMP5,MAP3K12,MPPE1" Drug 3377_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ASIC1,AK2,LTBP4,MRTFA,BIN1,CDC42BPA,SEMA7A,APC,EPB41L5,FAM131A,ATM,CFLAR,GYG2,LDLRAD4,FOXN3,CHM,STOML1,QKI,CTNND2,NOS1AP,HP1BP3,ATN1,HIPK3,FEM1B,EGFR,SPEG,FAM49B,OGA,GPR37,NR3C1,ATXN2L,IL6ST,KCNJ5,NDUFA5,PALM,PCDH9,MED1,RAD52,SLC1A7,COA1,KIF13A,RBM34,EMC1,ZNF423,SS18,TACC1,SMG6,PSD3,TGFBR3,TRIO,ZMYND8,KCNK12,ZNF24,REEP1,WNK1" Drug 4506_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "APAF1,CFLAR,BMPR1B,FUBP1,CD86,CRLF1,PLEKHB1,TAOK2,ARHGAP22,LHX2,STOML1,SEC14L5,EXOG,DUSP9,EFNA3,ELN,EPHA5,C1orf61,PDLIM5,FYB1,ATP8A2,GSN,PADI2,KLF12,SMAD1,SLCO1C1,NPPA,NUMA1,PDE4B,EPN1,CEP41,PTHLH,ELOVL2,ZSCAN2,KCTD17,MYH14,ROM1,KANSL3,SLC11A1,KIF13A,RBM34,TSNAXIP1,VAMP1,TACR1,SEMA4A,DMXL2,PCDHA6,AP4E1,TPM3,VAV2,SPHK2,REEP1,KCNAB1,EPM2A,GAN" Drug 3321_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ASIC1,AP2A2,SEMA6A,CDC42BPA,ASPH,CFLAR,BTRC,B4GALT6,TAOK2,CREM,LRIG1,SIPA1L1,CTH,RABGAP1L,DTNA,EFNA3,MBNL2,VPS13B,EPB41L2,LRRC23,CAMSAP1,DPYSL4,TRMO,GAB1,GCNT2,RUNDC3A,GLYR1,TDRKH,GPER1,SPACA9,NR3C1,INPP5B,IPO5,GIT1,NEK1,NF1,PDE3B,RETREG1,NLE1,ZSCAN32,RAB3IL1,ZCWPW1,SYBU,ZNF365,RBM34,KDM4B,KDM4C,STX1A,PLCB1,ATP11A,TRIM2,XRCC4,REEP1,WIPF2,UBE3B" Drug 4169_DN Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ADORA3,KIDINS220,BIN1,GAS7,CFAP410,CACNA1A,ARHGAP33,CNTN1,WHRN,SH2B1,CRY2,SNCAIP,SRGAP3,ELAVL2,ING4,SCML2,DLC1,C1orf61,SEPT9,ALDH1L1,SRCAP,LYVE1,GSN,SLC2A6,ATXN2L,HNMT,KCNJ5,KCNMA1,MAPT,ADAM22,MYT1,SNTG1,SERPINI1,LRP12,PPP2R2B,PRKCB,RAB3IL1,C1orf54,TRIM68,ZFHX4,TCP11L1,SBF1,SH3BP2,SH3GL3,PREX2,FAM214B,KIF13A,WDTC1,ZCCHC24,INKA2,SYT5,WSCD1,CDK20,FLRT2,MICAL1" Drug 5762_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ASIC1,ARID1A,ADRA1D,AP2A2,AMT,APC,ALDH7A1,SYNJ2,MYRF,BTRC,CBFA2T2,AP4M1,CRLF1,CHM,CHN2,RAB28,SULT4A1,TCEAL2,NECTIN3,VCAN,PDE4DIP,TBC1D5,RCAN1,MBNL2,EIF4G2,LRRC23,ZNF589,PRELID3A,PNMA2,OGA,GCNT2,SRCAP,GUCY1B1,INPP5B,KIF5C,NF1,NUMA1,NLE1,PEX5,RAD52,GAL3ST4,RGS10,SUGCT,ZNF671,MRAS,ASAP3,FUZ,SLC14A1,SNCA,DDN,CHST8,GPR161,TRPC1,UGT8,TIGD6" Drug 3197_DN Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ABHD6,MRTFA,CDC42BPA,PPFIA3,SEMA4G,DNAH17,MARK4,CA12,CAMK2G,KYAT1,SOCS6,PLAA,ARHGEF6,ARHGEF4,CYBB,TRAPPC9,CELSR3,HSD17B14,DMTN,KAT8,FGFR1,BAIAP2,FAM49B,GAB1,ZNF44,TDRKH,GRB10,GRM1,RNFT2,SLC2A6,HNMT,INPP5B,LMO2,MBD1,NF1,PC,PDE3B,CAMKV,CNNM2,GON4L,RALGDS,ZNF821,FNDC3A,ZNF365,SLC1A7,RBM34,WDTC1,STX1A,EXOC7,SMG6,DOCK9,CHST8,TMOD1,CABIN1,VIPR2" Drug 5633_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "NDRG2,LTBP4,BIN1,PPFIA3,AQP4,PPP4R4,CFLAR,SYNJ1,CFAP410,CAMK2B,CBFA2T2,CLGN,RCBTB2,RAB28,CLU,AKAP7,RCHY1,SH2B1,RIMS2,KBTBD11,SLC12A6,DRD1,EFNA3,ING4,LRRC23,ANKMY1,CAMSAP1,GABRA2,SYT17,GCNT2,SRCAP,MSL3,KCNMB4,CACFD1,RASSF8,TM6SF1,ZNF862,GRAMD1C,ZDHHC14,PREX2,SLC15A2,MAPKBP1,WDTC1,DOK5,SPART,TTBK2,PLCB1,ATP11A,CRTC1,TMOD1,FAM155A,ZFP37,ZNF711,ZNF45,ST7" Drug 6102_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "LTBP4,ALK,SEMA4G,ARSE,ADGRB2,SCAPER,CAST,CLGN,HOMER3,IFFO1,AATK,CSF1,TENM4,SPOCK2,ATN1,EFNB3,SORBS3,TNK2,DMTN,KCNMB2,EFCAB2,DPYSL4,FUT9,SRCAP,RND1,ATF7,ADAMTS13,PRDM5,GRM8,GSN,KCNH2,KCNJ5,KCNN2,SMAD1,SLCO1C1,NOVA2,OLR1,KCNK10,PFKFB2,SERPINE2,CDIP1,PPP5C,FAM120C,RGS12,ASAP3,CPEB3,SLC1A7,PKNOX2,ATP10B,SYP,SYT5,ZEB1,UBE3A,UGT8,WIPF1" Drug 3539_DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ARID1A,AP2A2,PLA2G6,AMT,CDC42BPA,APC,MARK4,ATM,MPDZ,CFLAR,NEURL1,CLGN,SRSF11,WHRN,ABI3BP,RIMS3,MAML1,RUSC2,EDNRA,EFNA3,EN2,VPS13B,NCALD,FER,FHL1,FLNC,FAM49B,OGA,GNG4,IL6ST,MAP4,MIA2,LYRM9,NF1,NNAT,NPTX1,PLEC,RALGDS,ROM1,SEMA6D,SH3BP2,MAPKBP1,EMC1,CLSTN2,PHLDB1,ROBO3,TCF7L2,AP4E1,THRA,PARD3,ZMYND8,ZKSCAN5,WNK1,MAP3K12,ACTR3B" Drug 4178_DN Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.48E-06 2.68E-01 1.03E-04 1.17E-03 55 194 "ADORA3,AP2A2,AMT,ATM,ATP2A2,CACNA1I,NEURL1,ASIC3,SLIT2,CRY2,DCAF4,SMG7,SRGAP3,DSCAM,DUSP9,ING4,ELN,DMTN,LRRC17,NCALD,DLC1,KHDRBS3,ERAP1,SEPT9,ALDH1L1,RND1,GNG3,ADAMTS13,CACFD1,NR3C1,KCNK2,KCNN1,KCNQ3,ADAM22,NF1,PRKCB,RAB3IL1,SBF1,NLGN1,SLC1A2,FAM214B,ZHX3,NPAS3,TROVE2,PLCB1,EXOC7,AP4E1,TMOD1,PARD3,CDK20,TPM2,TRO,WIPF1,WNK1,PLSCR4" Drug ctd:C520612 "N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid" CTD 5.48E-06 2.69E-01 1.03E-04 1.17E-03 17 35 "DLG4,GNAO1,GRIA2,GRID1,GRIK1,GRIN2D,GRM3,GRM5,PIK3R1,PLCL1,PPP3CB,PPP3CC,SLC1A2,SLC6A9,SLC8A3,SNAP25,SLC30A3" Drug CID000001388 MPTP-HCl Stitch 5.73E-06 2.81E-01 1.06E-04 1.21E-03 48 162 "ADORA2A,APAF1,APLP1,ARHGDIG,BCHE,CALB1,CALB2,AIFM1,CDC27,CDO1,CHRNA4,DRD1,EEF1A2,EYA1,PPP1R1B,GAD1,GAD2,GFAP,LOXL3,GPR37,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,LINGO1,MAOB,NOS1,SLC11A2,OGDH,OGG1,PENK,POU6F1,PTPRD,QDPR,HSPA4L,SNCB,SNCA,MGRN1,TK2,TMPO,SMUG1,PDIA2,PORCN" Drug 4445_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.76E-06 2.83E-01 1.06E-04 1.21E-03 53 185 "FAM135A,TRMT9B,GAS7,ATM,CADM3,N4BP2L1,KIF1A,CFLAR,GYG2,CBS,CDO1,CACNA2D2,CHI3L2,ZFYVE9,DNAJB5,CSF1,CTIF,MAGI2,NR1D2,ATN1,EDN1,EGFR,ETV1,CSPG5,OGA,RND1,MSL3,GNG4,PRUNE2,ATF7,GPR19,STON1,GUCY1A2,IGFBP1,KCNB1,KCNH2,SMAD1,AFDN,PDE4B,PGAM2,MAPK8,ACSS3,NTNG1,PREX2,ARHGEF40,HECW1,ARHGAP26,NPAS3,SZT2,AMACR,ZIC3,SYNC,PARP11" Drug CID000009308 muscarine Stitch 5.77E-06 2.83E-01 1.06E-04 1.21E-03 44 144 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,SLC24A4,BCHE,BSN,CACNA1B,CACNA2D1,AIFM1,CHRM1,CHRNA4,CHRNB2,SLC24A2,PLCXD3,DMPK,PNMA2,INPP5K,KCNMB4,PLCD4,KCNJ5,KCNK3,KCNMA1,MT3,NPY,P2RY1,PDE1C,PDE1B,PLCB2,PLCD1,PRKCB,PRKCG,ENOX1,SLC8A2,SLC8A1,SLC8A3,SOX1,SST,PLCB1,TAC1,TACR1,ALG1,PLD4" Drug 7075_UP AH6809; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ABHD6,NME5,C1QTNF1,AMPD3,BIN1,APBA2,APBB2,APC,PPFIA3,APP,OSGIN2,SOCS6,CHN2,CLCN3,QKI,BAG4,CPS1,CREM,ABCG1,USP6NL,KIAA0513,EDNRA,SIDT2,RBM12,GCNT2,GLI2,POLL,FERMT2,MAP4,MX1,NDP,PBX1,CEP41,TMEM104,RAD52,ARHGEF10L,SEC61A2,DOCK10,PEX26,CCDC88A,COA1,IFT122,KIF13A,KDM4B,PLCB1,TCF4,KIAA0930,ATP13A2,CABIN1,METTL3,VAV2,NPDC1,NDRG4,UPF3A,URM1,PHTF2" Drug 3839_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,NME5,SEMA7A,APLP1,RASL11B,SCAPER,NEURL1,PICK1,CNTN1,RIMS3,DBT,DTNA,DYRK1A,EGFR,EN2,LRRC17,F5,TUBB4A,FGF1,SCARA3,C1orf61,KHDRBS3,GABRA5,CPLX2,GCNT2,SRCAP,CSDC2,RUNDC3A,TDRKH,PCLO,C2orf72,KCNH2,KCNJ5,KCNQ3,MAP4,TM6SF1,MSR1,FXYD7,NEUROD1,NNAT,OMG,MAPK7,FAM120C,MYH14,DOCK10,ARHGEF40,FAIM2,KDM4B,IZUMO4,ZNF423,DMXL2,PIK3R5,SPHK2,EMSY,ADAMTS9,KAT6A" Drug 3038_DN Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "PKP4,APBB2,APOC1,AZGP1,NRP2,HIP1R,MAP7,CDH8,STOML1,ENTPD4,PDE4DIP,SLITRK5,RUBCN,DOCK4,ZNF337,TM9SF4,FAM13A,ABI2,SORBS3,MTSS1L,F5,ST3GAL6,CGREF1,ERAP1,INPP5K,GATM,PRRC2B,LILRA2,ATXN2L,ITGAM,LSS,SMAD1,MAP4,CNOT4,SLC25A23,LRP12,DEF8,PTCH1,RAD51D,ZDHHC14,SCN2B,SLC20A2,SNCA,SS18,PLCB1,KIAA1107,DMXL2,ZMAT3,TRPS1,FLRT2,LAT2,XRCC4,EMSY,HPS4,PHTF2,SSPN" Drug 5988_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ABHD6,LTBP4,GAS7,ATP1A2,CFLAR,BAIAP3,NGB,NEURL1,CACNA2D2,CLU,FAM189A2,QKI,WHRN,PDE4DIP,RIMS2,DTNA,PLXNC1,KCNMB2,FGFR3,TMEM8B,SIGLEC8,SRCAP,NR3C1,GRM1,HNMT,KCNJ5,KCNJ9,MSI1,NF1,OPCML,MTRF1L,PPP2R2B,MAPK7,MAPK10,PTPRO,RFX2,WLS,OGDHL,SNCA,KDM4C,ATP10B,PHLDB1,PLCB1,ZEB1,PCDHGA10,AP4E1,TK2,TMOD1,SEZ6L,RUNDC3B,VAV2,ZNF74,MVB12B,NUP214,TIGD6,SSPN" Drug 5988_DN Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SERPINA3,SLC12A5,MRTFA,AMH,ADAM23,ADAM15,BTRC,CA12,ARHGEF2,VAX2,AKAP7,CREM,CNTNAP2,EDRF1,TBC1D5,GIT2,TOM1,SEZ6L2,PLEKHO1,ACSL4,ZNF589,KIAA1109,GABRA2,USP19,TDRKH,NR3C1,GRM1,IL6R,IL6ST,INPP5B,ITPKB,MATK,MITF,CNOT4,NUMA1,ODF2,SLC25A23,PTN,PTPRE,ATG16L1,FBXW7,AMBRA1,CXXC4,MAPKBP1,SPTAN1,SPART,EXOC7,IQCE,TCF7L2,PSD3,AHCYL2,ZFP37,WNK1,GDPD5,SEMA3B,PCBP4" Drug 2985_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "RALGAPA1,ABAT,ABHD6,DOC2A,AMPH,APC,PDE8B,ATP2B3,NRP2,KALRN,CAMK2A,LARGE1,CHN2,TAOK2,STOML1,CNN3,NCOR2,SIPA1L1,PDE4DIP,MYEF2,MFAP3L,SPOCK3,SGK2,EGR3,EPB41L1,PRELID3A,NSG1,GAD1,MYOZ2,ADAM28,GLI2,GPM6B,RAPGEF1,GRM3,HPSE2,HTR2A,KCNQ3,SMAD1,AFDN,MSR1,NNAT,NPPA,NRCAM,OPCML,PDE4D,FSD1,PTPRN2,NEK11,SLCO1A2,TSNAXIP1,ADGRL3,TCF7L2,LILRA4,ZKSCAN5,FLRT2,SSPN" Drug 6731_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "DPF1,NME5,C1QTNF3,MADD,CDK13,CFAP410,CACNA2D1,SCARB1,CACNA2D2,ASIC3,CHN2,TAOK2,QKI,AKAP5,LRIG1,VCAN,CNTNAP2,CTNND2,RIMS2,TBC1D5,DAPK3,DCC,MFAP3L,RABGAP1L,DMPK,HIPK3,DLC1,CAMKK2,OGA,GNG3,GNG4,PRRC2B,ELOVL5,SHISAL1,IL12A,KCNMA1,ADAM11,MDM4,ADAM22,MX1,CNOT4,PBX1,SPATA6,CCDC40,RGS12,SCN3A,FAIM2,HECW1,ZNF423,TROVE2,TK2,TNS1,TPM3,ZMYND8,VLDLR,PARP11" Drug 5542_DN Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SERPINA3,APC,BCAS1,PDE8B,MARK4,CFLAR,CACNA1D,AP4M1,ARHGAP33,CREM,HINFP,PDE4DIP,CTNND2,GIT2,LYPD1,SMG7,DLG3,EXOG,EFNA3,CELSR3,ABI2,EML1,EPB41L1,EPB41L2,COQ7,ANKMY1,DISC1,SRCAP,SPACA9,KCNJ3,KIF5C,LMO2,MIA2,NFYA,NUCB1,PDE3B,PTPA,PTK2,RAD52,RGS10,RGS12,ROM1,SBF1,SGK1,FUZ,SLC1A7,PREX2,PPP4R3A,SLC22A4,ZCCHC24,EXOC7,ATP13A2,TGFBR3,PIK3R5,TPD52,CDK20" Drug 6929_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASPHD1,ASIC1,ADORA2A,AP2A2,KCNAB2,APBB2,CACNA1D,CCNT1,CRLF1,PLAA,TMEM59L,FADS2,QKI,NCOR2,RGS6,ARHGEF10,DCAF4,PARD6A,CDON,DSCAM,GNE,DMTN,F3,TRMO,FYN,EML4,TJAP1,ITPKB,ADAM22,NOVA2,NPTX1,NPTX2,PRPH,RAD52,UEVLD,FBXW7,EMID1,SBF1,SEC14L1,FBXO11,SLC22A4,KDM4C,CLASP2,ZC4H2,VAMP1,ARC,TNS1,PLPPR2,VAV2,KCNK12,ZBTB14,SPHK2,UPF3A,NAV2,MPPE1,ACTR3B" Drug 2198_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ABHD6,KIDINS220,BIN1,ANK3,CNTNAP1,APP,CDK10,ZSCAN18,DDX3Y,ALDH4A1,ADGRB1,CDC42,ZFYVE9,SULT4A1,CNTN1,CREM,ABCG1,SIPA1L1,DZIP3,MBNL2,EPHB1,ERBB2,CDKL3,FER,CAMSAP1,HPCAL4,FLT1,ANKFY1,B3GAT1,POLL,ATF7,STON1,GRM3,ICA1,KCNJ5,MEF2C,AFDN,MX1,PBX1,PDE4A,SLC25A23,POU6F1,CNNM2,FAM120C,RGS12,EMID1,SH3BGR,EPN2,SLC15A2,SLN,TNIK,ADGRL3,TCF4,SYNE1,TPM1,BEST1" Drug 3066_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "RALGAPA1,ABHD6,ADORA1,APC,SCAPER,THSD7A,NEURL1,SLIT2,ZFYVE9,DNAJB5,CNTN1,CRY2,CNTNAP2,CTIF,HS3ST2,EDNRA,EFNB3,SORBS3,ELAVL3,ZNF549,ETV1,KIAA1109,FGFR1,C1orf61,B3GAT1,KCNMB4,PADI2,KIF5C,MAP4,GIT1,NTRK2,PDE4D,PFKFB4,PLP1,SLC25A23,CEP41,CNNM2,RAD52,ZNF493,GAL3ST4,RGS12,ZFHX4,ANKRD6,SLC1A3,SNAP25,PALLD,PDZD2,PEG10,SEPT8,TBCEL,PCDHGA10,CRTC1,DICER1,TRPC1,NDRG4,FZD3" Drug 6752_UP Pipemidic acid [51940-44-4]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "RALGAPA1,NR0B1,EPB41L5,GAS7,PPP4R4,CDK13,SLC4A4,ST3GAL5,SCARB1,DLGAP1,EPS15L1,ABCG1,FEZ1,RIMS2,SPOCK2,MFAP3L,SV2B,DLG2,TENM1,F3,F5,CORO2B,PDLIM5,ALDH1L1,SRCAP,RND1,GNAL,GPR22,GSTM5,KLF12,SHISAL1,MDFI,TM6SF1,ADAM22,NTRK2,PALM,NLE1,DCHS2,ENOX1,RFX2,PKNOX2,SLC9A5,WDTC1,KDM4C,COLGALT2,PLCB1,SYN2,COBL,TAL1,TBCEL,DOCK9,BHLHB9,TPM3,HIRA,TFIP11,DPF3" Drug 2205_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADORA1,NME5,SRPX,FAM135A,BEGAIN,BIN1,DNAH17,BMP7,CAST,MAP7,CCK,USP2,TAOK2,AKAP6,NRG2,CRY2,RIMS2,CTIF,SMG7,EDNRA,SORBS3,CDKL3,OLFM1,FOXG1,PRELID3A,INPP5K,PRUNE2,GRM1,GSN,HAS2,ITIH2,MDFI,ADAM22,PFKFB4,PLCD1,NECAB2,PPARA,PRKAR1B,RELN,PTPRN2,GAL3ST4,EMID1,PPM1E,CPEB3,VAMP1,TACR1,ADGRL3,WSCD1,AHCYL2,ICAM5,TMOD1,SEZ6L,TRPC3,MAP3K12,SLC17A7,PHTF2" Drug 3750_UP Deltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "PKP4,GAS7,PPP4R4,ARHGDIG,CDK13,ASCL1,PDE8B,AZGP1,HIP1R,LARGE1,SLC24A2,SULT4A1,COL9A3,IFFO1,SUSD5,PHYHIP,MFAP3L,SV2B,MRNIP,RASGRP2,CEND1,FAM198B,SEMA4D,PDLIM5,GAB1,GALC,CYP46A1,ADAM28,PRUNE2,RAPGEF4,GRIK2,HTR2A,KCNB1,MAN2A2,MDM4,MYL3,NEUROD1,NUMA1,PDE3B,PNMA3,GDPD2,MYH14,EMID1,SEMA6D,ASIC4,SLC6A11,BTBD7,MYH15,DOK5,KDM4C,CUX2,HIF3A,NR2E1,CDK20,TUBB1,NLRP3" Drug 5782_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADORA2A,ABCD2,ANK1,FGD2,APAF1,BCAS1,KIF1A,MTMR3,GYG2,CACNA1D,CLDN10,INA,MAGI1,ADGRG1,CHI3L2,TAOK2,PICK1,WHRN,CRY2,FEZ1,CSNK1E,IPCEF1,RIMS3,EDN1,EFNB3,APC2,CORO2B,FGF1,AFF2,DCTN2,PRELID3A,GPR162,ADAMTS13,GRM1,PADI2,ELOVL5,KCNF1,KCNJ4,KITLG,TAGLN3,MYL3,NPR2,OPRL1,PTCH1,KLHDC8A,DZIP1,RPH3A,SHANK2,SNCA,KIF21B,KIAA1107,DAAM2,ETNPPL,KCNK12,ZNF711,REEP1" Drug 4392_UP Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,SEMA6A,MARK4,PTCH2,ATP1A3,NRP2,GYG2,SGCE,CACNB2,CHRNB2,AATK,CSF1,PARD6A,TMCC2,EFNB3,ATP8A1,KIAA1109,AGAP2,PDLIM5,GABRA2,GAD1,CPLX2,GNAO1,GPER1,ADAMTS13,IL11RA,ITGA7,ITIH2,KCNF1,KIF5A,MAPT,MEF2C,ADAM22,SLCO1C1,NOS1,NPY,OPRL1,CEP41,MAPK8,RGS4,RGS10,RPS20,SYNDIG1,RYR1,SATB1,ASAP3,RIMS1,SNCA,FAIM2,PEG10,ATP10B,KIAA1107,DOCK9,HEY2,KCNAB1,GJC2" Drug 6130_UP (R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SYT13,BIN1,FGF17,LDLRAD4,RGN,MAGI1,CRLF1,CHGA,DNAJB5,CREM,CRYBB1,ABCG1,SPOCK2,OPTN,EFNA3,TNK2,SRPK3,DMTN,RASGRP2,CEND1,DLC1,IQCG,PDLIM5,PCDH17,RND1,GRM1,GSTM5,IL1RAPL1,PADI2,KLF12,SCRG1,HPCA,ADAM22,SLCO1C1,FSD1,PPP2R2B,MAPK10,RELN,VPS13C,PTAFR,GAL3ST4,ZFHX4,MYH14,GALNT10,FERMT1,SLCO1A2,SMARCD3,PALLD,DOP1A,TROVE2,MCF2L,SPX,TK2,TRIO,UCHL1,SH3GLB2" Drug 4396_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC2,ASIC1,ADORA3,ADRA1B,C1QTNF1,BEGAIN,AMPH,APBA2,SEMA4G,CLDN10,NEURL1,GPR37L1,TAOK2,TPP1,CNTNAP2,ARHGAP24,SPOCK3,DMPK,OLFM1,FUT9,GCK,GRIK4,IRF8,IL11RA,KCNN2,LAMA2,MDFI,CD200,NPPA,OGG1,EPN1,PTAFR,PTX3,ZMAT4,RGS4,TMEM206,SLC1A7,SLC6A8,ARHGEF40,OGDHL,LIMCH1,SNCA,ARHGAP26,NPAS3,INKA2,AJAP1,MLC1,SYT5,POPDC3,ZEB1,TNS1,MKRN3,SPHK2,EVI5,ITM2C,MVB12B" Drug 2343_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,NDRG3,MTUS1,PROM1,CD86,CLCN4,IFFO1,CREM,SH2B1,CRY2,VCAN,CTNND1,ZFYVE16,RIMS3,SMG7,TRAPPC9,SIDT2,EIF4G2,ELAVL3,MRNIP,F5,ST3GAL6,ZNF589,ANKFY1,CELF1,GABRA4,GPM6B,GRIK1,KCNN1,TM6SF1,MPP2,NFYA,NLE1,POU3F2,PPP2R5C,PRKCZ,C1orf109,RIPOR1,RALGDS,RGS3,PBRM1,MRAS,FERMT1,CCDC88A,SLC15A2,ZNF667,KIF1B,ZBTB43,ATP10B,SYT11,SIN3B,PSD3,TRPC3,PLPPR2,MAP3K12,UBE3B" Drug 6974_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASPHD1,NME5,C1QTNF1,FAM131A,AQP4,CADM3,MTMR2,C5,RAB29,BAIAP3,BTRC,CAMK2B,CAMK2G,RAB33A,MAGI2,SGSM2,DTNA,OPTN,EIF5,ENO2,COQ7,RRAGB,FAM198B,ACSL4,ZNF589,ALDH1L1,MALT1,GLS,POLL,CACFD1,KIF5C,MAPT,TAGLN3,NPTX1,PDE3B,PDPK1,MTRF1L,MAPK7,RELN,NKAIN1,GTDC1,RGS12,ROBO1,SEC14L1,SLC1A7,ZCCHC24,TROVE2,FCHO1,ELOVL4,STX1A,VAMP1,PLCB1,TACC1,TPM1,AMACR,LMF1" Drug 7414_UP Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASPHD1,ARID1A,APAF1,BCAS1,ST3GAL5,BTRC,FADS2,CRMP1,CRY2,ARHGEF10,FAM169A,ARHGEF4,SNX29,EGR3,ELAVL4,COQ7,BAIAP2,SCARA3,B4GALNT1,SEPT9,GLS,POLL,GPR19,SPACA9,GRIK5,DHX35,JAK2,KITLG,NF1,SETD4,PDE3B,SERPINE2,PTPRE,RIPOR1,KCTD17,MYH14,GSTCD,MAPK12,SYBU,SLC1A7,PKNOX2,SMARCD3,MAPKBP1,KDM4B,TTBK2,RGL1,PHLDB1,ARHGEF9,PLCB1,ANKRD12,TEX15,ZNF34,ZNF24,ZNF45,NDRG4,NAV2" Drug 5738_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "AMH,APBB1,ARRB1,ALDH4A1,ADGRB1,BTRC,HAP1,CREM,ABCG1,MICAL2,CTIF,DTNA,EDIL3,EGFR,ING4,ELN,APC2,CDKL3,PTK2B,KIAA1109,TBR1,ZMYND11,GNG3,GPM6A,GRK4,GRM2,SOX21,ELOVL5,ICA1,KCNN2,LMO2,SMAD1,MATN3,AFF1,ADAM22,NUMA1,ODF2,OPCML,PKN2,MAPK8,RAD51D,C1orf54,ZCWPW1,RGS4,STUM,TMCC1,IZUMO4,LHPP,SEMA4A,DMXL2,PCDHGA10,PCDHGA1,PIK3R5,AMACR,NT5M,KCNAB1" Drug 7450_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,ABHD6,PLA2G6,BIN1,SEMA4G,CDK13,CFAP410,CACNA1A,CACNA1D,CACNG1,CLGN,FOXN3,CHM,CNTFR,SLC4A8,SIPA1L1,SEC14L5,TMCC2,EGFR,TUBB4A,KIAA1109,FGFR1,OGA,GAD2,HBS1L,MALT1,GLS,PRUNE2,TDRKH,KCNN1,MAP4,MMP16,ADAM22,MYO7A,NOVA2,NTRK2,PAX6,PCDHGC3,PDE4B,SERPINE2,PIK3CD,RIPOR1,RAD52,PAQR6,CLIP1,SLC11A1,SHANK2,ZCCHC24,PLCB1,TNS2,TIAM1,PIK3R5,CDK20,PLPPR2,TFIP11,SLC17A7" Drug 6308_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "MTUS1,BIN1,PPFIA3,ATM,CFLAR,SCAPER,TENM4,PPP6R2,GPRASP1,ARHGAP24,RIMS3,GIT2,CNIH3,C2CD2L,SMG7,DLG3,DYNC1I1,SIDT2,ERCC2,CGREF1,INPP5K,GNAS,GSN,BACH2,SYNPO,KCNMA1,MN1,ZNF862,NDP,NPR2,OGG1,PC,NLE1,PLCD1,FSD1,PPP3CC,PRPH,CNNM2,ELOVL2,SH3TC2,FAT4,PEX26,ELMO2,UNC5B,SS18,ELOVL4,PLCB1,SYT1,EXOC7,TRIM2,MAP3K12,GDPD5,NAV3,URM1,WIPF2,PHTF2" Drug 3821_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ARID1A,ADORA3,APAF1,APBB1,BMPR1B,HAP1,CD86,DLGAP2,TPP1,FAM189A2,AKAP6,CRMP1,CTIF,DCC,EDIL3,LRRC17,IGSF6,ST3GAL6,FGFR3,HPCAL4,GAD2,NEU3,RAB30,GRM8,GSTM5,HRH3,ATXN2L,KCNB1,KCND3,MAN2A2,MEF2C,ZNF862,P2RY13,NF1,NPPA,NPTX1,SNTG1,PFKFB4,POU6F1,LRRN3,CEP41,ELOVL2,ZMAT4,RET,RGS12,RNASE1,RNASEL,KLHDC8A,RAVER2,IZUMO4,MAPK8IP3,VAMP1,TAC3,ICAM5,FLRT2,SLC13A3" Drug 1699_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "BIN1,APBA2,PPP4R4,SLC4A4,ATP6V0A1,SCAPER,CACNA1I,CA4,HAP1,CACNA2D2,SLIT2,SLC4A8,NECTIN3,DAPK3,NR1D2,EDNRA,PLXNC1,PLEKHA1,ZNF589,KIAA1109,ERAP1,CSDC2,GLYR1,GNG3,TDRKH,KCNK1,MAP4,MBD1,MSI1,NF1,NFYA,SETD4,PDE4A,NLE1,PLCD1,PMP22,MAPK8,WDR25,PTAFR,PEX5,GTDC1,SCN8A,STUM,ASAP3,PKNOX2,SNCA,SPART,STX1A,PLCB1,ARC,PCDHGA1,TEX15,TRPC1,ZKSCAN5,VIPR2,GDPD5" Drug 7133_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADRA1D,KIDINS220,PPP4R4,PDE8B,MARK4,ATP2A2,SCARB1,RAB28,CLCN4,DNAJB5,HOMER3,CSF1R,OSBPL3,CNIH3,RUSC2,SMG7,DTNA,MBNL2,EN2,DMTN,ZNF391,SPEG,CDKL3,TESK2,SCARA3,PDLIM5,OGA,ZMYND11,SIGLEC8,GFER,CRCP,MSL3,NR3C1,IL6ST,IL11RA,JAK2,LIG4,MX1,LYRM9,PLCD1,PTHLH,TMEM231,DOCK10,NLGN1,LIMCH1,DDN,SAMSN1,ELOVL4,SYT1,TCF4,NSD1,TRPM2,TRPS1,TFIP11,WNK1,HPS4" Drug 3803_UP Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "LTBP4,APC,DDX3Y,N4BP2L1,NRP2,GYG2,HAP1,KCNAB3,CHI3L2,STOML1,CABP1,ARHGEF10,SMG7,AK5,DLG4,PLXNC1,FGR,AFF2,PDLIM5,GATM,SRCAP,GFRA1,CSDC2,RAB30,POLL,GPM6B,GRM7,NXPH3,PTGDR2,HSD17B1,KCNJ4,LMO1,MARK1,KITLG,MMP17,ADAM22,NF1,NTRK2,NTRK3,P2RX7,PDE2A,PDYN,NECAB2,PTPRG,RAVER2,SH3BP2,SLN,SSTR1,CRB1,TPM3,VAV1,VLDLR,WIPF1,PARP6,SLC17A7,MVB12B" Drug 4255_UP "Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SPARCL1,BEGAIN,PKP4,ZSCAN18,BACH1,ADGRB3,BCL2L2,SYNJ2,MTMR3,THSD7A,USP2,VAX2,FAM149A,CSF1,CNTNAP2,SRGAP3,DMPK,ATN1,DSCAM,DTNA,EDN3,EDNRA,TENM1,EPHB1,ZNF391,PTK2B,CORO2B,FGF12,AFF2,DENND2A,GAP43,ERAP1,NEU3,PCDH17,GRIK5,ITIH2,MMP16,SLCO1C1,NNAT,CAMKV,GAL3ST4,NEK11,NTNG1,PREX2,PKNOX2,CXXC4,SNCA,TNIK,TROVE2,TBL1X,ZNF34,TPM2,TRPC1,CADM1,UBE3A,KAT6A" Drug 3073_UP Flucytosine [2022-85-7]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SYN3,CDC42BPA,ANK3,BCAS1,ARRB1,DNAH17,MYOM1,CFAP410,CACNB4,CHGA,TAOK2,DNAJB5,CNTN1,CREM,ABCG1,RIPOR2,DGKB,SV2A,DSCAM,EEF1A2,SORBS3,EPB41,ETV1,PDLIM5,CGREF1,GAD2,ALDH1L1,RUNDC3A,GLRB,GNG3,IL1RAPL1,KCNQ3,MAP4,AFDN,TAGLN3,MYT1,NOS1,NRCAM,PCDH9,PLEC,PPP2R2B,PPP5C,GAL3ST4,ZFHX4,ST6GAL1,RPH3A,CXXC4,DOK5,SZT2,PSD3,ICAM5,CLIP2,SPHK2,STMN4,NAV2,SSPN" Drug 1797_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "NDRG3,BRAP,KIDINS220,ARNTL,STX16,BTRC,KIAA1549L,NMT2,ABI3BP,MATR3,ZNF804A,SPOCK3,G3BP2,DTNA,DUSP9,BAIAP2,SEMA4D,TRMO,SPIN1,HTATSF1,GRIK2,GRM5,HNMT,MDFI,NASP,NFYA,PIK3R1,ZFYVE21,MAPK3,CNTLN,RAD52,FAT4,RBBP6,SUPT20H,SH3GL3,FNDC3A,SLC1A2,SLC4A3,CCDC88A,WDTC1,DOK5,ARHGAP26,CLASP2,CEP68,VPS13A,ATP11A,SATB2,TNS2,TMEM121,METTL3,HIRA,BCL2L13,XRCC4,SPHK2,ZBTB38,AAAS" Drug 6125_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADORA1,DOC2A,AMH,BIN1,ANK2,FGD2,APOC1,CDC14B,MTMR3,CACNA1I,CBFA2T2,CLCN4,CREM,ABCG1,RIMS3,SPOCK2,SV2B,ATN1,HEYL,SORBS3,SRPK3,DMTN,RASGRP2,SCARA3,CAMKK2,PCLO,WIF1,INSM1,MT1M,MYH6,NRCAM,PPP2R2B,MAPK8,RELN,PTPRH,RGS4,NEK11,SYNDIG1,SALL1,SCN8A,GALNT10,SLC1A2,SLC1A3,PREX2,SLC9A5,SHANK2,CXXC4,TMCC1,SYT5,CAMSAP2,TCF4,DOCK9,ATP13A2,SPHK2,ZNF225,PLSCR4" Drug 4230_UP Minaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADORA1,DDO,ARSE,ATP2B2,NOL4,RGS9,CACNA1G,KALRN,ENTPD2,VAX2,CNTFR,AKAP6,COL9A3,NCAN,PDE4DIP,CNTNAP2,SRGAP3,DMD,EPHB1,ZNF549,PTK2B,FGF12,CAMSAP1,AFF2,EFCAB2,GABRA3,GAP43,SIGLEC8,GFER,PRUNE2,GRM8,ATXN2L,SMAD1,MAG,MAP2,AFDN,NOS1,NTRK2,PCDH8,NECAB2,MAPK8,DCHS2,MASP1,KHDRBS2,ZFP2,SLC6A9,SNCA,ZNF415,SP2,SYT5,TAC3,MCF2L,KLHL4,RIMBP2,TRPC3,TUBB1" Drug 2754_DN Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "AK2,APC,CDK10,ASPH,ATP6V0A1,ADAM15,GYG2,PLAA,FAM189A2,MAP4K4,COL9A2,PDE4DIP,DZIP3,CTNND2,HP1BP3,C2CD2L,DSCAM,RCAN1,TSPAN5,SUGP2,TNK2,MRNIP,ENO2,EZH1,KAT8,KIAA1109,FGFR1,SRCAP,PACSIN2,ITPKB,LIG4,KITLG,MKLN1,CNOT4,SLC11A2,PC,PCDH9,CCSER2,ZSCAN32,ZCWPW1,GTDC1,GSTCD,FOXRED2,ITSN1,PEX26,SMTN,SLC22A4,ZSWIM8,CLASP2,ASTN2,TACC1,PCDHA6,AP4E1,HPS4,SMIM8,RNF170" Drug 5637_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ACTN2,ADORA1,ADRA1D,KIDINS220,BIN1,AQP4,PPP4R4,PDE8B,GYG2,CACNA1I,LDLRAD4,HAP1,CAMK2G,CBFA2T2,SCARB1,CDH8,CLGN,CHRNB2,STOML1,FADS2,QKI,SULT4A1,NRG2,CRY2,RCAN1,DTNA,OPTN,EFNA3,EGFR,ELAVL3,EML1,FAM49B,FYN,GAB1,GAD2,SRCAP,RAB30,IL6R,KITLG,AFF1,NEUROD1,NF1,NPTX1,PDE1C,GRAMD1C,BTBD7,WDTC1,TROVE2,PLCB1,TGFBR3,CABIN1,ZKSCAN5,ZFP37,ZNF711,SLC17A7,ADAMTSL3" Drug 2094_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "MRTFA,BEGAIN,PPFIA4,ASCL1,SYNGR3,PLEKHB1,STOML1,DNAJB5,CNR1,SH2B1,SEC14L5,CTIF,MFAP3L,PLPPR4,HIPK3,SORBS3,PLEKHA1,ANKMY1,FGF1,BAIAP2,GNG4,CACFD1,IGSF1,ITGA7,MMP16,GIT1,MYO7A,NTRK2,PDE1C,PDE4D,WDR25,CNTLN,ELOVL2,SUSD4,GAL3ST4,RGS4,TTLL7,SH3BP2,SLA,RPH3A,PKNOX2,SHANK2,COLGALT2,PHLDB1,ACSBG1,CHST8,TIAM1,TK2,TRPC1,RPRM,VGF,REEP1,SH3GLB2,NT5M,STMN4,SLC17A7" Drug 4346_DN (S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADRA1D,NME5,MRTFA,APBA2,APP,CFLAR,CACNA1I,BAIAP3,LRRFIP1,CDH18,FOXN3,CHRNB2,QKI,PICK1,WHRN,CSF1,CTNND2,PPP6R2,MFAP3L,DLG3,ING4,TNK2,VPS13B,F3,FER,BAIAP2,GPR153,ALDH1L1,RND1,GLS,GNAS,GRIK5,ATXN2L,IL6ST,KHK,MID1,GIT1,LYRM9,NEK1,NPR2,NPTX1,PLXNB1,ELOVL2,PTN,ZSCAN32,ZFHX4,MYH14,SAFB,ZCCHC24,TSNAXIP1,CLSTN2,ATP11A,WSCD1,PSD3,HEY2,KCNK12" Drug 5050_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "GRAMD1B,APAF1,CDK10,ST3GAL5,KALRN,HAP1,SCARB1,DNAJB5,WHRN,CABP1,FAM131B,MFAP3L,DYRK1A,EDIL3,HIPK3,COQ7,SPEG,PTK2B,HPCAL4,PRELID3A,SYT17,RUNDC3A,RND1,GLYR1,GPER1,GRIK5,LIFR,VWA5A,NPTX2,NTRK2,CLDN11,PFKFB2,PLCD1,SPATA6,TNPO2,PPARA,CEP41,PRKAR1B,CNNM2,PLPPR1,PTPRB,RAD52,FAT4,GAL3ST4,RGS10,TCP11L1,ST6GAL1,ZHX3,SPTB,PHLDB1,SLC44A1,TPM3,WIPF1,ZNF74,ZNF225,PARP6" Drug 7306_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "DOC2A,CDK13,NCOA1,ADAM23,CFLAR,BTRC,HAP1,CDC42,ARHGAP33,ZFYVE9,HOMER3,CTNND2,TOX,C2CD2L,HS3ST2,EGFR,ING4,EPB41L2,FYN,GAB1,GABRA2,ERAP1,ALDH1L1,GRM8,TJAP1,ITIH2,KPNA5,LSS,ADAM11,SETD4,PDE4D,PENK,CNNM2,PEX5,RET,TTLL7,CARF,TRAPPC13,ZNF821,DZIP1,SLC1A3,SLC1A7,PEX26,IFT122,ZC3H13,ARHGAP26,SPTAN1,SS18,PLCB1,SYT1,ASTN2,PCDHA2,AHCYL2,RIMBP2,TRPC3,NT5M" Drug 4334_UP 0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASPHD1,ASIC1,ADCY2,TRMT9B,APAF1,ARRB1,ASPH,CADM3,BAIAP3,HAP1,RUNX1T1,CLCN3,CNTFR,RIMS2,RIPOR2,CTIF,SMG7,DTNA,NCALD,PTK2B,AGAP2,PADI2,AGFG1,IFI16,IL6ST,KCNN2,MAP4,TM6SF1,MMP16,ADAM22,NF1,NFIX,NUMA1,PBX1,PFKFB4,PIK3R1,STRN3,PRKAB2,CEP41,ACSS3,RFX2,KIRREL1,SYNDIG1,NTNG1,SLC15A2,ARHGEF12,DICER1,SLC44A1,TMPO,TNS1,VSNL1,SF1,ZIC3,WNK1,KCNAB1,KAT6A" Drug 2882_UP Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,AP2A2,PLA2G4C,GYG2,CACNA1I,CFAP410,CACNA1A,CAMK2B,CBFA2T2,ARHGAP33,CLGN,STOML1,DNAJB5,ARHGEF6,TCEAL2,SPOCK2,CNIH3,DTNA,EFNB3,EGFR,ERBB4,ERCC2,TUBB4A,DLC1,FGR,AFF2,FAM49B,SRCAP,GPER1,SPACA9,HLF,ITGAM,NDUFA5,NF1,PCBP3,NUMA1,TMOD2,SLC25A23,PRKCB,PTPRN2,KLHL11,ZFHX4,MYH14,EMID1,KCNIP1,ZNF821,SHANK2,BTBD7,SNCA,SOX2,INKA2,SYNE1,PCDHA5,PCDHA3,SLC44A1,VAV2" Drug 6906_UP STOCK1N-28457; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ACTN2,ADORA1,NME5,APAF1,APLP1,APOC1,APP,SHTN1,KSR1,SYNJ2,SCAPER,CA12,SEPT7,ZFYVE9,NMT2,FADS2,KIAA0586,ATN1,DUSP9,ERCC2,IGSF6,F3,TRMO,RUNDC3A,ZNF276,ATXN2L,DHX35,KIF5C,MIA2,MOBP,MPP2,LYRM9,PHKG1,PPM1B,RELN,RAB3A,RGS12,EMID1,HUNK,MAPK12,SH3BGR,FBXO11,PREX2,SHANK2,LIMCH1,SNCA,KDM4B,TSNAXIP1,CLASP2,ZNF302,TMEM121,PARD3,PIK3R5,TPM1,XRCC4,PLSCR4" Drug 5960_DN estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "APBB1,APBB2,GAS7,KIF1A,MAP7,CCNT1,SYNGR3,SEPT7,TAOK2,NRXN3,TPP1,HOMER3,SLC4A8,TCEAL2,CREM,HINFP,AATK,CSF1R,RIMS3,DMPK,SGK2,HIPK3,SIDT2,SCML2,FGFR1,FYN,GAB1,TRAF3IP2,POLL,PRRC2B,GPM6B,GPR17,INPP5B,KIFC3,NF1,OPCML,EPN1,ZSCAN32,PTPRH,RAB3A,RGS4,RXRA,SCN2A,SUPT20H,DZIP1,SMARCC2,LIMCH1,ASTN2,RPGRIP1L,CRTC1,RUNDC3B,TSN,UGT8,ZNF711,SPHK2,EVI5" Drug 3349_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,NDRG3,ALCAM,KCNAB2,PDE8B,MARK4,SCAPER,CA4,HAP1,ARHGEF1,CACNA2D2,CLU,AKAP7,WHRN,CSF1,ARHGEF10,SDC3,DOCK4,PARD6A,RABGAP1L,EXOG,EGFR,LRRC23,CDKL3,HBS1L,NR3C1,HNMT,ICA1,MID1,MMP16,ADAM22,MYO7A,NPTX1,SLC11A2,PENK,MAPK7,PRODH,CNNM2,PTN,GTDC1,FERMT1,IQSEC2,ZBTB43,ELOVL4,STX1A,CHST8,TNS1,TRPC1,ZKSCAN5,VLDLR,WIPF1,KCNK12,XRCC4,SYNC,MPPE1,SSPN" Drug 6053_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,NDRG2,ADCY2,ADORA1,PLA2G6,LTBP4,BIN1,APBA2,GAS7,BTRC,CACNA1D,SEPT7,CRLF1,FOXN3,TAOK2,ABI3BP,CRMP1,CSF1,RASSF2,DAPK3,MAGI2,TOM1,EFNA3,FYB1,GABRA2,GAD2,SRCAP,MSL3,POLL,NR3C1,GRM1,RASSF8,MATK,ZNF862,RAB3A,ZDHHC14,SEMA6D,NLGN1,PKNOX2,SLN,DOP1A,TSNAXIP1,ZHX3,ZC3H13,NCDN,MAPK8IP3,VAMP1,ZEB1,SZT2,PARD3,VGF,XRCC4,KCNAB1,PLSCR4,KAT6A,NUP214" Drug 1987_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,ACLY,NDRG3,BRAP,PLA2G6,PKP4,DGKD,SHROOM2,CDC14B,ARNTL,CFLAR,BMP7,MTMR2,BTRC,HIP1R,KRIT1,INA,FAM189A2,QKI,ZNF337,ZNF804A,ZEB2,C2CD2L,G3BP2,RCAN1,SGK2,FCGRT,GAA,GALC,ARFIP1,GRB10,IFI16,KIF5A,KIFC3,MX1,NEK1,NFYA,NRGN,NTRK2,NTRK3,OGG1,ENPP2,PLCD1,RAP1GAP,BSDC1,ZNF821,FAM102A,AMBRA1,SNAP25,SRPK2,NSFL1C,CAMSAP2,NPL,ZMYND8,SLC26A10,EVI5" Drug 3570_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "SPARCL1,LTBP4,CDC42BPA,APC,EPB41L5,CHRD,ATM,CFLAR,SYNJ1,SYNJ2,CFAP410,SLC16A4,QKI,COL9A3,NECTIN3,CNTNAP2,DCAF4,CYBB,RIMS3,ATN1,C3orf18,EN2,STX2,GALC,SPACA9,GRM1,GSTM5,GUCY1A2,VSIG4,INPP5B,KCNN1,MAP2,MAPT,ADAM22,NEUROD1,NF1,P2RY1,CDK14,MINDY2,PRODH,RELN,RGS12,ZNF821,PREX2,ARHGEF40,COA1,LIMCH1,TSNAXIP1,VAMP1,SYT5,DMXL2,SLC44A1,WIPF1,SYNC,SLC30A3,GDPD5" Drug 3764_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "KLRC4,ADD2,C1QTNF3,BEGAIN,BCAS1,CDC14B,ASTN1,ATP1A2,ATP2B3,FUBP1,LDLRAD4,CAPN3,RHBDL1,LDB2,CHRNA4,KIAA1549L,SULT4A1,CNTFR,FAM149A,CSF1,FEZ1,ATN1,DTNA,HEYL,PLXNC1,LRRC23,NCALD,ST3GAL6,C1orf61,FYB1,DKK3,SIGLEC8,ALDH1L1,PCDH17,C1QL1,GNAL,GNG4,GRM2,SOX21,NXPH3,ATXN2L,HTR2A,C2orf72,KCNMA1,MAN2A2,NUMA1,PDE2A,C19orf57,PSD,RGS12,CNKSR2,SLC9A5,ATP10B,TRPC3,TUBB1,EVI5" Drug 2549_UP Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADCY2,ADGRF5,ANK3,PPP4R4,MYOM1,KIF1A,MPDZ,RGS9,NRP2,GYG2,NEURL1,TAOK2,LHX2,QKI,CSF1,PDE4DIP,PPP1R16B,RUBCN,DCC,TMCC2,HS3ST2,EIF4G2,FGFR1,NSG1,GABRA1,GABRA2,GAD1,RUNDC3A,GLYR1,GLRB,C2orf72,MYBPC1,NEUROD1,NRCAM,DDR2,OPCML,ENPP2,PMP2,PPARA,MAPK8,MYH14,SEMA6D,ZNF365,SLC1A6,TMCC1,RBM34,SPTB,ATP10B,INKA2,TAC3,ROBO3,AHCYL2,TEK,TRO,ZMYND8,ZBTB38" Drug 3186_UP Amodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADCYAP1R1,AP2A2,C1QTNF1,ARHGDIG,DDX3Y,ATP1A2,CACNA1I,BAIAP3,BTRC,HAP1,RUNX1T1,NEURL1,JAM2,EPS15L1,AKAP6,WHRN,MYRIP,MYEF2,DMPK,TRAPPC9,EDNRB,SORBS3,PIPOX,RASL12,BAIAP2,FHL1,FLNC,GAD1,NEU3,JAK2,KCNQ2,KPNA5,MDFI,MITF,MSR1,MYL3,MYO7A,NECAB2,CEP41,MYH14,RPS6KA2,SLC1A2,SHANK2,ZCCHC24,IZUMO4,LMO3,EPB41L3,MAPK8IP3,SLC35G2,TIMP4,DAAM2,PIK3R5,CHST5,MKRN3,LAMP5,NUP214" Drug 6486_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ADGRF5,CDC42BPA,PPP4R4,RGS20,ATP1A2,LDLRAD4,CA4,NEURL1,GREB1,KIAA0319,KBTBD11,DRD1,ATN1,RCAN1,ANKMY1,PRELID3A,B3GAT1,TBR1,ALDH1L1,SRCAP,POLL,GPM6B,NR3C1,LIG4,MAOB,MSI1,NEUROD1,NOVA2,PLCD1,LRRN3,PPP5C,RELN,PTAFR,PTPRB,RAB3A,RGS3,SEMA6D,MRAS,HECW1,SAMSN1,THSD1,INKA2,PLCB1,TAC3,WSCD1,TRIM2,PCDHGB6,PSD3,CRTC1,BEX4,CABIN1,TNS1,VIPR2,CLIP2,NSD2,SLC30A3" Drug 2454_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "BEGAIN,ANK1,APAF1,FAM131A,AQP4,CDC14B,ARHGDIG,N4BP2L1,RIPK1,KIF1A,CFLAR,BTRC,RUNX1T1,INA,CDH10,SLIT2,AKAP6,SIPA1L1,GPRASP1,ARHGAP32,DAPK3,DCT,ABCC9,FCF1,EIF1,FGF12,BAIAP2,DENND2A,SIGLEC8,SRCAP,GPM6B,TPPP,ITIH2,KCNJ5,MYCN,NFYA,PDE2A,PLCD1,EPB41L4B,WDR25,KHDRBS2,PLPPR3,FOXRED2,KDM4B,TROVE2,NXT2,SYT5,WWC1,CUX2,PIK3R5,TPM3,TRIO,ZMYND8,VAV2,NSD2,ADAMTS9" Drug 4177_UP Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC2,NR0B1,BIN1,APAF1,APBA2,GAS7,AQP6,CDC14B,ASTN1,ATP1A3,KSR1,MTMR3,CAMK2B,CAST,KCNAB3,TPP1,AKAP6,MICAL2,VCAN,CNTNAP2,CDON,RASGRP2,F5,TUBB4A,CORO2B,ZNF589,AGAP2,FYB1,SRCAP,PCDH17,GLS,GUCY1A1,GUCY1B1,KCNJ9,MID1,MYH7,NPTX2,OGG1,KCNK10,EPN1,CEP41,ELOVL2,KLHDC8A,NTNG1,CNKSR2,SLC11A1,SMARCA4,SOX10,SP2,SYN2,PCDHGB6,TMEM151B,SLC35G2,TRIO,NT5M,STMN4" Drug 4749_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ASIC1,LTBP4,ALK,AMPH,CNTNAP1,DNAH17,MARK4,MTMR7,DNAJB5,COL9A3,AKAP5,INTS1,NTM,DTNB,ELAVL2,ING4,ELAVL3,ZNF589,FGFR1,FHL1,FOXG1,CSPG5,ZNF44,GAD2,HBS1L,DISC1,SRCAP,CSDC2,IRF8,TJAP1,KCNH2,KCNMA1,MATK,ADAM22,NTRK2,NTRK3,PHKG1,PLCB2,EPN1,PTAFR,PTX3,RAD52,SLA,LIMS2,LIMCH1,INKA2,MAPK8IP3,VAMP1,POPDC3,PIK3R5,VGF,LAT2,SYNC,SLC30A3,SLC17A7,KCNAB1" Drug 2579_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "ABAT,AMH,ANK3,PKP4,PRX,INA,NEURL1,CDC42,LHX2,EPS15L1,HOMER3,SLITRK5,DAPK3,HIPK3,EFNA3,ERBB2,CEND1,PTK2B,FGFR1,FOXG1,NBEA,CAMKK2,KHDRBS3,GPR153,ERAP1,GCNT2,ZNF276,GNG4,GPD2,LILRA2,GSN,RASSF8,TJAP1,KCND3,LSS,TAGLN3,MX1,PDE3B,PURG,EPB41L4B,TNPO2,POU3F2,POU6F1,CNNM2,PTPRB,RXRA,SH3BGR,SLC1A2,PALLD,ATP10B,PHLDB1,EXOC7,PSD3,RBFOX2,CHST5,PARP11" Drug 4595_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.78E-06 2.83E-01 1.06E-04 1.21E-03 56 199 "PLA2G6,C1QTNF3,ALK,GAS7,BCAS1,CADM3,BMPR1B,ARHGEF2,LARGE1,CHI3L2,B4GALT6,RAB28,CLCN4,CREM,CREB5,ABCG1,CNTNAP2,ARHGEF4,CTNND2,MFAP3L,AK5,RABGAP1L,ST8SIA3,EDN1,EFNB3,F5,CORO2B,KIAA1109,BAIAP2,TRMO,GAB1,ZNF44,DISC1,GCNT2,TDRKH,GPR22,TPPP,MMP16,NEFH,NF1,NOVA2,PDE4A,PENK,PFKFB4,PTPRB,ACSS3,CCDC40,KLHDC8A,SOX15,UNC5B,NPAS3,SZT2,PCDHGA10,TNS1,UCHL1,GAN" Drug CID000104978 fluo-3 Stitch 5.83E-06 2.86E-01 1.07E-04 1.22E-03 39 122 "ADORA1,AGT,PHF12,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,KRIT1,EDN1,EDNRA,LPAR6,ATP2C1,GJB1,KCNMB4,GRIK1,GRIK3,GRIN2C,GRIN2D,CIT,KCNMA1,LSAMP,NACA,P2RX7,P2RY1,ABCB1,PRKCB,PRKCG,PTPRD,QDPR,RYR1,RYR3,RIMS1,TMPO" Drug CID000002414 AC1L1DME Stitch 5.91E-06 2.90E-01 1.08E-04 1.23E-03 28 76 "CD86,CD38,CDR1,CHRM1,VCAN,MALT1,INSM2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KITLG,PPP5C,MAPK7,DDN" Drug CID000005279 NSC618487 Stitch 6.00E-06 2.94E-01 1.10E-04 1.25E-03 197 935 "CLK4,ADCY5,ADCY6,ADCY8,ADRA1B,AGT,PLA2G6,ANK1,MYH7B,APAF1,APBB2,DGKZ,DGKD,APP,MADD,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BID,CFLAR,BTK,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAST,MAP7,CCK,KRIT1,RGN,AIFM1,SCARB1,DGKI,LRBA,ZBED1,CDH2,CHRM1,TAOK2,CLU,MYL6B,SNCAIP,CSF1,FEZ1,CSNK1E,PLCXD3,MAML1,DGKB,DGKG,DAPK3,SLC12A6,ABI1,EDN1,EDN3,EDNRA,EGFR,IRAK4,TNK2,EPHA5,EPHB1,ERBB4,PTK2B,FCGR3A,FDFT1,FER,FGF1,ACTL6B,FGFR1,FGFR3,FGR,SYNCRIP,USP16,CAMKK2,ATP2C1,FYN,GAP43,NEU3,MSTN,GHR,GRB10,PLCD4,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GSN,MAP4K5,TNFAIP8L3,HSF2,MYLK2,IGF1,IGFBP1,SCIN,IL6ST,ITGAM,JAK1,JAK2,KCNA1,KCNA2,KCNA4,KCNA6,KCNJ3,KCNJ4,KCNJ5,KIT,STMN1,ASPRV1,MAPT,MATK,MBP,BLOC1S2,MYL3,MYT1,NCF2,NODAL,NOS1,NPPA,NUMA1,P2RY1,PAK3,PDPK1,ABCB1,PHKG1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,MBOAT7,PPP2R2B,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,KLK6,PSMA6,PTHLH,PTK2,PTPN13,RAB5B,SEC61A2,PCMTD2,BAALC,RPS6KA2,MAPK12,SMPD3,SELL,SLA,SLC6A1,SIRT2,SLC12A4,TMEM132D,SNAP25,SNCB,SNCA,TNIK,PEG10,STAU1,ADHFE1,NSFL1C,PLCB1,SYT1,TEK,LEFTY2,TJP1,ACTR6,ZFP91,TNFRSF1B,CABIN1,TTPA,BCL2L13,VGF,NDRG4,PLPPR5,PLD4,PAK5,CAMK1G" Drug CID000005206 sevoflurane Stitch 6.10E-06 2.99E-01 1.12E-04 1.27E-03 35 105 "ADORA1,KYAT1,CRY2,PLCXD3,TRAPPC9,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GPT2,GRIA1,PLCD4,TNFAIP8L3,KCNA1,KCNA2,NBL1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,RYR1,RYR3,ARX,DDN,PLCB1,ZFP90" Drug 4307_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.12E-06 3.00E-01 1.12E-04 1.27E-03 54 190 "MTUS1,CDC42BPA,PKP4,APOC1,ASPH,ALDH7A1,SPAG9,SRSF11,ENTPD4,SMG7,EXOG,FCF1,SIDT2,IRAK4,STX2,VPS26C,ZNF44,SPIN1,HTATSF1,FERMT2,AGFG1,IFI16,IL6ST,MAP4,MMP16,NFIX,CNOT4,NUMA1,STRN3,MED1,PKN2,PTPRH,SLC25A36,KIRREL1,SEC14L1,PPP1R9A,CCDC88A,ZNF667,ZBTB43,TBL1X,EHBP1,TCF4,PSD3,DICER1,CBX5,TMPO,R3HDM1,VIPR2,SF1,ZNF74,ZBTB38,SYNC,WNK1,KAT6A" Drug 331_UP trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 6.12E-06 3.00E-01 1.12E-04 1.27E-03 54 190 "ASIC1,ABHD6,ADD3,NME5,MARK4,BMP7,RAB29,BAIAP3,CLGN,SLIT2,RAB28,WHRN,ARMCX2,DNAJC6,DRP2,EFNA3,EFNB3,BSCL2,ENO2,SPEG,F5,PCYOX1,POMT1,FYN,CYP46A1,RUNDC3A,RAB40B,TDRKH,RNFT2,KIF5C,MXI1,CDK18,SERPINI1,PIK3CD,CCSER2,PLCD1,ZNF821,SH3BGR,SH3GL3,ANKRD6,WDR47,FAM214B,PKNOX2,ZCCHC24,NMNAT2,RGL1,STXBP1,ACSBG1,TRIM2,WASHC4,AHCYL2,DNAJC12,PLPPR2,SLC17A7" Drug 6825_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-06 3.00E-01 1.12E-04 1.27E-03 54 190 "ACTN2,NDRG2,MRTFA,SEMA4G,ARRB1,PDE8B,SLC4A4,ALDH7A1,ADAM23,AZGP1,BAIAP3,CCKBR,CLGN,RCBTB2,SULT4A1,PLCH2,SPOCK2,RUSC2,ATN1,EFNB3,EFS,RASL12,ST3GAL6,FGF1,FYN,ALDH1L1,SRCAP,RND1,GNG3,IL6R,KCNQ3,PDE4A,CEP41,MAPK10,SAMD9,RAD52,TTLL7,ASIC4,ST6GAL1,FAM214B,SLC6A9,ZCCHC24,SPART,MAPK8IP3,ACSBG1,ARC,WSCD1,TRIM2,TEX15,ZKSCAN5,FAM155A,KCNK12,ZNF154,PARP11" Drug 3379_DN Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-06 3.00E-01 1.12E-04 1.27E-03 54 190 "CDC42BPA,MPDZ,CFLAR,ADGRG1,FOXN3,SOCS6,B4GALT6,LHX2,RAB28,QKI,ARMC8,DNAJC6,MFAP3L,LYPD1,DLG3,DTNA,STX2,FGFR3,BAIAP2,SYNCRIP,PDLIM5,MALT1,TXNL4A,SLC2A6,MUM1,JAK2,KLC1,KITLG,MMP16,MPP2,NEK1,CEP97,GTDC1,ZNF821,ITSN1,SHANK2,BTBD7,ZHX3,SPART,CLASP2,TROVE2,THSD1,TACC1,TCF7,TNS2,TMEM121,BEX4,RPRM,VAV2,ZBTB14,ZIC1,REEP1,ST7,ZNF248" Drug 6844_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-06 3.00E-01 1.12E-04 1.27E-03 54 190 "BIN1,RGS20,BAIAP3,HIP1R,ARHGEF2,CLGN,ADGRG1,CLU,SULT4A1,WHRN,NECTIN3,CREM,CYBB,HS3ST2,TRAPPC9,DRD1,DTNA,SNX29,C3orf18,ENO2,KCNMB2,RND1,TPPP,GRB10,GRM1,GRM2,HPSE2,IL6R,MX1,ZNF862,NAP1L2,TMOD2,PTCH1,ZSCAN2,RGS12,TTLL7,TCP11L1,SH3BGR,ASAP3,FAM214B,BTBD7,ZCCHC24,TSNAXIP1,IZUMO4,VAMP1,WSCD1,ZEB1,TF,UCHL1,VLDLR,XRCC4,KCNAB1,MVB12B,KAT6A" Drug CID000004799 AC1L1IZE Stitch 6.15E-06 3.01E-01 1.12E-04 1.28E-03 41 131 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,ADRA1D,APC,GPAM,PDXK,DNAH17,DYNLL1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,KIF1A,KRIT1,P2RX6,ENTPD2,DNAL1,DNAH9,TUBB4A,ATP2C1,ATP8A2,LPAR4,DDX19B,KCNJ3,KCNK3,SMAD1,KITLG,MYO7A,P2RY13,P2RX7,P2RY1,OLA1,MAPK10,RYR1,RYR3,MAPK12,P2RY12,DNAH10" Drug 1398_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; HL60; HG-U133A Broad Institute CMAP Up 6.21E-06 3.05E-01 1.13E-04 1.29E-03 49 167 "ADD3,BIN1,APAF1,GAS7,ARRB2,DNAH17,CFLAR,SLC25A14,CD86,CD38,ARHGAP33,FOXN3,CHN2,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,GIT2,SH3GLB1,FAM13A,LPAR6,EPB41L2,OGA,TRAF3IP2,MALT1,GLUL,PACSIN2,HNMT,NCF2,ODF2,OLR1,PDE4B,PDE4D,GPSM2,PLCD1,SMOX,QDPR,SGK1,SLA,ATF7IP,LMBRD1,ZSWIM8,BEX1,SPTAN1,EPB41L3,PLCB1,TPM4,FLRT2" Drug CID000005255 N-Ac-D-E Stitch 6.24E-06 3.06E-01 1.14E-04 1.30E-03 22 53 "ASPA,NCAN,FOLH1,GAD1,GAD2,GFAP,GRIK1,GRIK2,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GPSM2,PLP1,SLC15A2,SYNE1,GJC2" Drug 5743_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.43E-06 3.15E-01 1.17E-04 1.33E-03 52 181 "LHX2,SNPH,HDAC4,RASSF2,KLHL3,TMCC2,ABCC5,EIF5,TNK2,ETV1,TBC1D16,ST3GAL6,TESK2,FAM49B,CGREF1,SESN1,GLRB,GUCY1A1,ITPKB,MARK3,SCAMP5,PDCD2,PDE4A,KCTD15,MBOAT7,MINDY2,MAPK7,RAB3A,RALGDS,SH3TC2,RAP1GAP,GTDC1,RFX5,RGS3,CCDC25,LGR4,FAM102A,ST6GAL1,FAM214B,PDZD2,TNIK,CDK19,DIP2A,TBL1X,TRIM2,GPR161,NACC2,HEY1,HIRA,MVB12B,FZD3,MARCH8" Drug 4162_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ADCY2,KLRC4,AK2,APAF1,CDC14B,BRINP2,ADAM23,CA4,CACNG1,CALB1,RUNX1T1,CDH2,CRLF1,CHRNB2,TPP1,STOML1,ATRNL1,SPOCK3,DMPK,HS3ST2,DRD1,ATN1,DTNB,MTSS1L,GAD1,HPGDS,GPM6A,GPER1,GRK4,GUCY1A2,HPSE2,L1CAM,TAGLN3,ZNF862,NOVA2,NPTX1,TREM2,CDIP1,MAPK7,DCHS2,ROM1,OGDHL,LIMCH1,FAIM2,NMNAT2,MAPK8IP3,PHLDB1,ACSBG1,SYP,ATP11A,DOCK9,TF,XRCC4,FAM13C,JPH3" Drug 7135_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "KIDINS220,AMPD3,PPFIA3,APP,CDK10,ALDH4A1,CA12,PTBP2,CACNA2D2,LHX2,CPS1,DTNA,AASS,VPS13B,TUBB4A,OLFM1,FGFR1,BAIAP2,AFF2,CINP,ERAP1,TMEM8B,SEPT9,GPM6B,GPR17,MAN1B1,SYNPO,KIF5C,LSS,MEF2C,PCDH9,KCTD15,MAPK7,CNNM2,PTN,TMEM231,SH3TC2,SEC61A2,GSTCD,MCMBP,SCN8A,FNDC3A,PEX26,SLC6A8,SNCA,POGZ,SYT1,PSD3,DNAH7,SPX,TNS1,VGF,LMF1,WNT7A,UPF3A" Drug 3610_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "SPARCL1,GAS7,CADM3,N4BP2L1,CACNA2D1,ENTPD2,NCOR2,FAM169A,DGKG,GIT2,SRGAP3,DTNA,EDN1,EDN3,ERCC2,FGF1,FGFR1,AFF2,FOLR2,KHDRBS3,GABRA5,ALDH1L1,ADAM28,RND1,HTR2A,MGAT3,MYH6,ZNF862,NCF2,NF1,CDK18,ENPP2,PLCD1,RAD52,KCNIP2,SH3BP2,HKDC1,PKNOX2,LIMCH1,PDZD2,IZUMO4,UNC5B,ZNF423,SPTB,TACR1,WSCD1,PCDHGB6,CRTC1,TIMP4,TPM3,TRH,TTPA,UCHL1,WNT7A,SPHK2" Drug 6424_DN F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "AMH,OGT,EPB41L5,APOC1,PPP4R4,ZBTB10,EIF4G3,CFLAR,SCAPER,CA12,CDC27,CDC42,CLGN,RAB26,COL4A5,NECTIN3,CSF1R,PDE4DIP,RABGAP1L,DNAH9,ATN1,F3,DLC1,ALDH1L1,COPS8,KCNMB4,STON1,GPR37,NR3C1,HNMT,ICA1,BRINP3,KCNJ3,MAN2A2,MEIS1,MPP2,ADAM22,ZCWPW1,KCTD17,TCP11L1,EMID1,PAQR6,LIMS2,LIMCH1,KIF13A,KDM4B,SPTAN1,ITPRID2,THSD1,WWC1,KIAA0930,TPD52,WRN,PRDM2,RNF170" Drug 4122_UP Boldine [476-70-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASPHD1,ACTN2,SPARCL1,ALCAM,AMPD3,GAS7,KSR1,CACNA1I,CLDN10,RAB33A,CLCN4,SULT4A1,COL9A3,LYPD1,ATN1,SNX29,EFNB3,EGFR,MBNL2,VPS13B,MTSS1L,SCML2,DLC1,FHL1,DCTN2,OGA,RND1,SOX21,ICA1,KCNJ5,KCNK2,KCNN1,MATN3,ADAM22,NF1,NTRK2,SERPINE2,RETREG1,GDPD2,GSTCD,TCP11L1,EMID1,RPS20,STUM,SH3BP2,PPP1R9A,ST6GAL1,SP4,PHLDB1,JMJD6,KIAA1107,TCF7,HIF3A,PARP11,PAK5" Drug 4170_DN Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASIC1,ADORA3,AMPD3,GAS7,PLA2G4C,DNAH17,ALDH7A1,CACNA1I,CFAP410,CA4,CACNB2,HAP1,SLC16A4,CDH18,FOXN3,CLTB,FADS2,SNCAIP,CSF1R,PDE4DIP,NOS1AP,SPOCK2,DYRK1A,EDNRB,HIPK3,ERCC2,PIPOX,DLC1,ZNF589,GAD2,DISC1,NEU3,ALDH1L1,RND1,TJAP1,JAK2,KCNN2,GIT1,ADAM22,NEUROD1,NF1,SAMD9,C1orf54,TRIM68,SH3BP2,SH3GL3,KIF13A,ZCCHC24,TSNAXIP1,SYT5,TBCEL,KIAA0930,AP4E1,XRCC4,KCNAB1" Drug 6104_UP Propidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "NDRG2,C1QTNF3,ANK1,RGS20,ASCL1,ADGRB1,NRP2,GYG2,CA4,CHRNA4,CNTNAP2,RASSF2,EXOG,ATN1,EDN1,EFNB3,TNK2,SPEG,PIPOX,ZNF44,RUNDC3A,GPM6B,ATF7,ADAMTS13,C2orf72,KCNH2,MAOB,AFDN,MYT1,NF1,NOVA2,P2RX7,TREM2,PDE4D,PGAM2,DUSP26,RETREG1,GDPD2,RGS12,SYNDIG1,CLIP1,SH3BP2,BEX1,CDK19,ATP11A,DNAH7,DAAM2,R3HDM1,TRIO,TTPA,TUBB1,ITM2C,MVB12B,NUP214,JPH3" Drug 7403_UP Lisinopril [83915-83-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ABHD6,NDRG2,APBB2,APC,PPFIA3,CFLAR,CDK5R1,SCAPER,FOXN3,SLIT2,TCEAL2,ENTPD4,PPP6R2,DAPK1,GIT2,DBN1,FBXL5,EIF5,TNK2,MRNIP,F8,FGFR1,SCARA3,GFER,MALT1,COPS8,GRB10,SPACA9,LIG4,AFDN,MSI1,ADAM22,NELL2,NOS1,NUMA1,PDE1C,PLCD1,FSD1,RIPOR1,RPS6KA2,SEMA6D,RPH3A,CLASP2,VAMP1,PLCB1,IQCE,WSCD1,DOCK9,PSD3,PARD3,PIK3R5,VLDLR,HPS4,MPPE1,UBE3B" Drug 3977_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "RALGAPA1,ASIC1,ADORA1,AP2A2,AMPD3,SEMA7A,KCNAB2,GAS7,RGS20,PDE8B,MARK4,BRINP2,CFAP410,SLC16A4,ARHGEF1,CLTB,RIMS2,EDRF1,RUSC2,DMPK,DUSP9,HIPK3,FER,SRCAP,RUNDC3A,GLS,KIF5A,MAN2A2,MAOB,MPP2,BCO1,MSR1,CDK18,PLCD1,STRN3,MINDY2,MAPK7,PTHLH,PTPRD,EMID1,SEMA6D,ZNF821,PREX2,TSNAXIP1,SP4,ATP10B,THSD1,POPDC3,CRTC1,SLC35G2,RUNDC3B,HIRA,LAT2,ZFP37,SYNC" Drug 3885_UP Flutamide [13311-84-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASIC1,C1QTNF1,SEMA6A,AMPD3,FGD2,APAF1,ATP1A2,BACH1,ADGRB1,LDLRAD4,RUNX1T1,ZFYVE9,TPP1,LY86,VCAN,SPOCK2,HEPH,EDN1,ELAVL3,C3orf18,RASGRP2,DLC1,CAMSAP1,AGAP2,GAB1,GATM,GLYR1,PCLO,TPPP,GRM1,HTR2A,INPP5B,MMP16,ADAM22,MAPK7,ZSCAN32,SCN8A,SH3BP2,CPEB3,BCAN,LIMS2,SLC11A1,INKA2,MAPK8IP3,TBL1X,WSCD1,DOCK9,SLC35G2,HEY1,TNFRSF1B,HIRA,VIPR2,LAT2,PLSCR4,SENP7" Drug 2748_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "APBA2,PPFIA3,APP,PLA2G4C,ATP2A2,ST3GAL5,BAIAP3,LDLRAD4,CACNA1D,ARHGAP33,SULT4A1,HOMER3,TCEAL2,NRG2,TENM4,DOCK4,DBN1,ZNF804A,SPOCK3,DNM1,EDNRB,EN2,CDKL3,C1orf61,GFER,RND1,GLS,STON1,NR3C1,GSN,KHK,MAP4,GIT1,PALM,PLCB2,ZDHHC14,KCTD17,RPS6KA2,SYNDIG1,FOXRED2,SH3BP2,PPP1R9A,CPEB3,SNCA,ZCCHC24,HECW1,VAMP1,KIAA1107,TNS2,TEX15,CHST8,HEY2,UBE3A,VIPR2,WIPF1" Drug 5053_DN Antimycin A [1397-94-0]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ACTN1,NME5,KCNAB2,PPFIA3,MARK4,SCAPER,BTRC,MAP7,CBFA2T2,CSF1R,VCAN,HDAC9,TOX,TBC1D5,KBTBD11,EIF5,HSD17B14,EPB41L1,DMTN,ATP8A1,BAIAP2,CINP,TMEM8B,CNTRL,NR3C1,BACH2,KPNA5,NDUFA5,LRP12,BCAS3,FAM120C,SH3TC2,RPS6KA2,TMEM156,SUPT20H,ZFP30,DZIP1,BTBD7,ZHX3,CAND2,BEX1,PBLD,ELOVL4,ARHGEF9,SYT1,ROBO3,SLC35G2,AHCYL2,TRPS1,UGT8,PLPPR2,SPHK2,TFIP11,PMEPA1,EPM2A" Drug 1520_DN Azacyclonol [115-46-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "SLC12A5,LTBP4,DOC2A,GAS7,APLP1,MARK4,KIF1A,GYG2,CACNA1D,HAP1,CAMK2G,CRLF1,TAOK2,LHX2,SULT4A1,ARMC8,COL4A5,SH2B1,CSNK1E,MAML1,TMCC2,ACSL4,FER,PCYOX1,CSPG5,MALT1,GLYR1,KIF5C,SCAMP5,MMP16,NPTX1,PDE3B,SSH1,MBOAT7,GTDC1,RGS12,GSTCD,MCMBP,FAM192A,SUPT20H,ASAP3,SMTN,SLC15A2,LIMCH1,MAPKBP1,WDTC1,MAPK8IP3,KIAA0930,PCDHA6,PLPPR2,EMSY,ST7,SMIM8,PHTF2,ZNF248" Drug 2820_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "RALGAPA1,AP2A2,NME5,ALCAM,APBB2,GAS7,ARHGDIG,CFAP410,ARHGEF2,CDH10,ADGRG1,LHX2,FAM189A2,SH2B1,CSF1R,FAM169A,SPOCK2,DTNA,ZNF589,KIAA1109,BAIAP2,FHL1,SEMA4D,GPR153,CNTRL,HNMT,INPP5B,KCNH2,LMO2,MOBP,MX1,LYRM9,ZNF862,PDE4A,SLC25A23,PRPH,RAD51D,RAD52,ZDHHC14,ABLIM3,PEX26,SLC22A4,ZHX3,TSPYL2,CAMTA2,EXOC7,SYNE1,ARHGEF12,TK2,TMOD1,PARD3,MICAL1,DNALI1,GDPD5,EPM2A" Drug 2517_UP Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ADCY6,SEMA6A,BBOX1,ANK3,PPFIA2,SEMA4G,ATP2B2,ADGRB2,CACNA1G,CACNB4,CAMK2B,AKAP5,HAPLN1,CNTNAP2,BRINP1,EDNRB,EPB41,EPHB1,FLT1,AFF2,GAB1,ARPP21,LYVE1,TOX3,GNAL,GRK4,GUCY1A2,HSD17B1,KCND3,KCNJ5,KCNN1,LAMA2,MEF2C,CD200,NEFM,NEUROD1,SNTG1,RASGRF1,SEC14L1,CNKSR2,ST8SIA1,EPN2,KANSL3,LIMCH1,SNAP25,SPTAN1,SSTR2,TCF7L2,TRIM2,CRTC1,TEX15,SEZ6L,LILRA4,PRDM2,JPH3" Drug 6415_UP Orlistat; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "TTYH1,ADD2,BIN1,CDK13,ADGRB2,SYNJ2,CHN2,CLCN4,CSF1,VCAN,C2CD2L,HIPK3,SPEG,DLC1,FYN,GAB1,GABRB1,DISC1,GCK,GFER,TOX3,MSL3,GPM6B,GRK4,GRM2,INPP5B,KCND3,KCNN1,LIFR,FXYD7,NF1,NPPA,PLCD1,PTH1R,PTPRH,CCDC40,RGS4,KCTD17,RPS20,STUM,FNDC3A,ST6GAL1,SLC1A7,ZKSCAN3,UNC5B,SPTAN1,JMJD6,CUX2,TRIO,TRO,FAM155A,WIPF1,ITM2C,MVB12B,PAK5" Drug 2225_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "DPF1,NME5,ANK1,APLP1,PDE8B,PTCH2,ATP1A2,ATP2B2,CADM3,CFLAR,BAIAP3,CAMK2B,AKAP6,CNTNAP2,MAML1,RUSC2,NTM,DNAH9,ATN1,HIPK3,VPS13B,MTSS1L,KIAA1109,OGA,GAP43,SIGLEC8,LYVE1,GPR22,NR3C1,HPSE2,IRF8,ITGAM,KCNJ4,KCNMA1,KCNQ3,MBD1,MEF2C,PURG,CDIP1,LRP12,POU3F4,PRKCB,PTPRO,RAD52,RYR1,SATB1,PKNOX2,SLC11A1,LIMCH1,HECW1,PEG10,VAMP1,ZMYND8,PLSCR4,DPF3" Drug 2478_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "NDRG3,ALAD,MRTFA,APAF1,CDK10,NCOA1,STX16,CFLAR,MYRF,CACNB2,CD86,SOCS6,CNOT8,PLAA,IQCK,SH2B1,CRY2,DOCK4,RIMS3,DBT,ABI2,ERCC2,SCML2,ZNF589,KIAA1109,FGFR1,EML4,TJAP1,JAK2,ZNF862,NCAM1,CNOT4,NLE1,PRKCZ,PTPRN2,RAB3IL1,RGS10,SEC14L1,MRAS,SH3BP2,FBXO11,EPN2,IZUMO4,SPART,FCHO1,NCDN,ADGRL3,TCF4,TCF7L2,ZEB1,SMUG1,LMF1,ZNF24,UPF3A,WNK1" Drug 6822_UP Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ACTN2,AP2A2,MRTFA,BEGAIN,AMT,ANK1,SYNJ1,CA4,CACNG1,CBFA2T2,PICK1,NECTIN3,ATRNL1,DCAF4,SPOCK2,DNAJC6,RUSC2,ECM2,EDN1,VPS13B,ERCC2,ETV1,KAT8,PDLIM5,FYN,CSDC2,SPACA9,GRM1,GRM2,GUCY1A2,HLF,ITGAM,KCNMA1,KCNQ3,AFF1,NEUROD1,NOVA1,NPTX2,PDE1C,C19orf57,PTHLH,RGS12,TCP11L1,RPH3A,FAM214B,SNCA,ZNF423,SYN2,SYP,WSCD1,GPR161,RUNDC3B,WIPF1,XRCC4,KCNAB1" Drug 5093_DN Carbamazepine [298-46-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ARID1A,AMT,STX16,ADGRB2,FUBP1,CACNA1A,SCARB1,CHM,SLC4A8,RCHY1,CPS1,CSF1R,ARHGAP24,BRINP1,SMG7,SGSM2,CDON,EDIL3,FCF1,EGFR,MBNL2,MTSS1L,KIAA1109,ANKFY1,OGA,GAB1,GLYR1,MSL3,GPD2,PCLO,GRM1,AGFG1,KCNN1,MAPT,MMP16,NF1,CLDN11,PBX1,PCDH9,RAB3IL1,RAP1GAP,GSTCD,LIMS2,SNCA,WDTC1,TNIK,NXT2,JMJD6,DNAH7,XRCC4,ZNF711,ZNF24,SEMA3B,KAT6A,SENP7" Drug 2808_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "AP2A2,CDC42BPA,EPB41L5,ARRB2,CFLAR,SPAG9,CD81,CLCN3,NIPBL,AKAP7,ENTPD4,CRY2,SOCS5,DZIP3,CTNND2,EDRF1,GPRASP1,GIT2,DTNA,FEM1B,ING4,EML1,EZH1,BAIAP2,GHR,TXNL4A,HNMT,HSD17B1,IL6ST,KCNH2,KCNJ3,MEIS2,NEK1,OGG1,RETREG1,PLXNB1,NDUFS7,ELOVL2,NKAIN1,TMEM231,MYH14,COA1,FAM168A,EXOC7,PSD3,TMPO,ZMYND8,HIRA,UBE3A,BCL2L13,MFF,PCBP4,PHTF2,ZNF248,SSPN" Drug 5582_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "DPF1,TTYH1,SYN3,NDRG2,ASCL1,BRINP2,CADM3,N4BP2L1,RGS11,BSN,CACNA1D,CBFA2T2,ARHGEF2,CACNA2D2,SULT4A1,IFFO1,ARHGEF4,MYEF2,RUSC2,MBNL2,PLXNC1,ELAVL3,VPS13B,MTSS1L,IGSF6,SPEG,CAMKK2,GAD1,GLYR1,GNAL,NXPH3,KCND3,ADAM22,MSR1,MYO7A,NOVA1,NTRK2,OMG,PCDH9,PHKG1,PLCB2,ZNF493,BEND5,EMID1,SH3BP2,CNKSR2,IZUMO4,ATP10B,TAC3,ROBO3,DOCK9,HIF3A,GPR161,R3HDM1,KCNAB1" Drug 4577_UP Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "DPF1,RALGAPA1,AGT,EP400,APBB1,GAS7,CFLAR,RAB29,KRIT1,LARGE1,CHN2,CLCN4,QKI,TCEAL2,CREM,PDE4DIP,CNTNAP2,PHF14,GIT2,AK5,RCAN1,SUGP2,KCTD3,IRAK4,ETV1,EFEMP1,TRMO,DENND2A,SOX21,JAK2,NF1,NNAT,GPR85,PIK3R1,TNPO2,MINDY2,PKN2,SNRK,MYH14,FBXW7,CLIP1,TMEM156,PPP4R3A,FAM214B,RAB3GAP1,BTBD7,KDM4C,SS18,ASTN2,TCF4,PCDHA5,GPR161,ZMYND8,SLC17A7,PHTF2" Drug 433_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "NDRG2,MPDZ,BMP7,SYNJ1,RAB29,NEURL1,CHN2,CHRM4,CHRNA4,CNR1,ABCG1,ARHGEF10,C2CD2L,ACSL4,FER,AGAP2,AFF2,DPYSL4,GAD1,DISC1,PRRC2B,GPM6B,GUCY1B1,DIPK1A,KIF5C,MITF,MMP16,MYO9A,NOS1,PCBP3,PACSIN1,PPARA,MINDY2,MASP1,TMEM104,DCUN1D2,TCP11L1,WLS,CSRNP3,ASAP3,SLC9A5,TNIK,SPTB,SPART,VPS13A,COBL,TBL1X,TCF4,DMXL2,FLRT1,LMF1,SLC13A3,SLC26A10,GDPD5,MPPE1" Drug 4508_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ADORA2A,MTUS1,MRTFA,APC,APOC1,PDE8B,ASPH,ALDH4A1,ALDH7A1,KIF1A,SCAPER,IL33,BTRC,CCNT1,CHM,ZFYVE9,LY86,ABCG1,SMG7,RABGAP1L,EGFR,PLXNC1,LRRC23,STX2,KIAA1109,PDLIM5,GAB1,RASSF8,ATXN2L,IL6ST,KIF5C,MDM4,MMP16,NF1,PPP5C,MAPK8,GON4L,PLPPR1,TMEM231,PID1,ZCWPW1,SEC14L1,SLC11A1,WDTC1,BEX1,DDN,MAPK8IP3,SYN2,TAL1,TBL1X,PSD3,TEX15,TMPO,FAM155A,NUP214" Drug 4845_UP Primaquine diphosphate [63-45-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ACHE,NDRG2,CDC42BPA,GAS7,DDO,DNAH17,SLC4A4,ADAM23,KSR1,CBFA2T2,CDH2,LHX2,NRG2,CSF1,SEC14L5,MFAP3L,DRP2,ST8SIA3,AASS,ELN,CDHR1,CEND1,ACSL4,DLC1,ST3GAL6,GABRA2,LYVE1,RND1,GNAL,GRM1,GUCY1A2,MID1,ADAM22,NACA,NPPA,NTRK2,OPRL1,MTRF1L,POU6F1,PPARA,RELN,PEX5,RAB3IL1,KHDRBS2,MYH15,IQSEC2,DDN,ATP10B,ARC,POPDC3,ADGRL3,OSBP2,VIPR2,LAT2,NT5M" Drug 3508_DN Risperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ABHD6,AP2A2,AK2,BEGAIN,DOC2A,PPP4R4,PDE8B,MARK4,RASL11B,KIF1A,NEURL1,ABI3BP,GREB1,JAKMIP2,EIF5,ING4,VPS13B,STX2,ACSL4,FGFR1,BAIAP2,PRKAG2,FHL1,CINP,PRELID3A,OGA,GAD1,TDRKH,SPACA9,HNMT,NF1,CNOT4,NPTX1,OGG1,OPCML,RETREG1,ZCWPW1,RGS10,GSTCD,CCDC25,EMID1,WLS,SEMA6D,FNDC3A,WDTC1,EMC1,POGZ,MAPK8IP3,ZEB1,AP4E1,TMOD1,CABIN1,ZMYND8,ZKSCAN5,SEMA3B" Drug 7468_UP Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASPHD1,ASIC1,SEMA6A,BIN1,RGS20,N4BP2L1,BMP7,CACNA1I,CAMK2G,USP2,FOXN3,AKAP7,HDAC9,TBC1D5,MFAP3L,TMCC2,DNM1,SGK2,EFNA3,SUGP2,EGFR,EPB41L1,F5,PTK2B,ERAP1,INPP5K,TDRKH,GPR37,IL6R,KCNN1,MAP4,MATK,AFF1,ADAM22,NF1,NOVA2,NPTX1,RETREG1,PLXNB1,RIPOR1,MYH14,WLS,SH3BP2,SH3GL3,WDTC1,KDM4C,IQSEC2,TSPYL2,STX1A,PLCB1,PCDHA5,TIAM1,R3HDM1,VAV1,SEMA3B" Drug 4634_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASPHD1,ADCY6,MTUS1,KCNAB2,GAS7,SLC4A4,B3GALT2,ST3GAL5,CACNA1G,CFAP410,ARHGEF2,SOCS6,CLCN4,TPP1,TMEM59L,RAB26,HAPLN1,VCAN,PDE4DIP,SIDT2,ATP8A1,SIGLEC8,SRCAP,TDRKH,GRK4,HNMT,ICA1,SHISAL1,KCNH1,KCNJ5,GIT1,CLDN11,PAK3,PTCH1,C1orf54,KLHL11,SLC11A1,SLC20A2,HECW1,BEX1,ARHGAP26,ELOVL4,ASTN2,TAC1,TACR1,TBCEL,TCF4,DOCK9,CRB1,SLC44A1,SSBP2,FLRT2,VIPR2,NAV3,SLC17A7" Drug 4576_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ASPHD1,SYN3,ACTN2,FAM135A,TRMT9B,CDK10,PPP4R4,ASTN1,NRP2,GYG2,CACNA1I,CACNA1G,CA4,SLC16A4,CD86,NEURL1,CRLF1,SULT4A1,CNTFR,VCAN,SPOCK2,AASS,RASGRP2,CAMSAP1,PNMA2,GAB1,GABRA2,GLS,HSD17B1,KCND3,ADAM22,NOVA2,PDGFRA,PENK,PMP2,MINDY2,GDPD2,ZMAT4,CARF,SCN2A,FRMPD1,NLGN1,SLA,SLC8A1,SLC11A1,OGDHL,SNAP25,TSNAXIP1,RBM26,ATP10B,PCDHGA10,HIF3A,AMOT,VAV2,SLC17A7" Drug 5763_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "ARID1A,NME5,SLC4A4,ALDH7A1,CDK5R1,MYRF,CA8,NEURL1,CDC42,CRLF1,RAB28,SULT4A1,ARHGEF10,CTNND2,EDRF1,ARHGAP24,MFAP3L,DRP2,DTNA,TENM1,LRRC17,FGFR1,BAIAP2,SEMA4D,ZNF276,INPP5B,LIFR,MAP2,MMP16,GIT1,NDP,NOVA2,NPR2,CNNM2,SAMD9,PEX5,RAD52,FAM184A,SUGCT,SALL1,MRAS,SLCO1A2,SNCA,ZNF415,ZHX3,DDN,ZEB1,CABIN1,TNS1,CADM1,REEP1,MAP3K12,SCG2,TIGD6,DPF3" Drug 3840_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "AMH,GAS7,ARRB1,SYNJ2,BTRC,CHM,CNOT8,TAOK2,RAB28,SIPA1L1,RIMS2,EDRF1,DCAF8,DAPK3,DTNA,EFNA3,MBNL2,LRRC23,KIAA1109,GAB1,GLYR1,GPD2,GPR19,IGSF1,MPP2,ADAM22,ZNF862,NEK1,NPR2,NUMA1,PLCD1,ZSCAN32,ZSCAN2,RAD52,RALGDS,ATG16L1,RGS10,ROM1,RPS6KA2,EMID1,ZNF821,ASAP3,FUZ,FNDC3A,WDTC1,CDK19,EXOC7,KIAA1107,FBXW11,KIAA0930,KAT6B,ZKSCAN5,VIPR2,SNX27,PHTF2" Drug 6245_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.47E-06 3.17E-01 1.17E-04 1.33E-03 55 195 "NDRG2,GAS7,APLP1,BCL7A,BAIAP3,CAMK2G,ADGRG1,EPS15L1,RAB28,VAX2,QKI,SULT4A1,HOMER3,PDE4DIP,HDAC4,CTIF,EDN3,EGR3,TNK2,PLEKHO1,TUBB4A,CNTRL,SPACA9,GRM1,INPP5B,KCNB1,ADAM22,RETREG1,MAPK7,CEP97,KHDRBS2,GSTCD,KCNIP1,SGK1,FNDC3A,SYBU,NLGN1,SNCA,WDTC1,ZHX3,ARHGAP26,SPTAN1,CDK19,PLCB1,ASTN2,ATP11A,ANKRD12,EXOC7,TNS2,ATP13A2,CABIN1,TSC2,PLPPR2,SPHK2,SEMA3B" Drug CID000107778 HU-211 Stitch 6.76E-06 3.32E-01 1.21E-04 1.38E-03 37 114 "ADCY5,CBR1,CBS,CNR1,EDIL3,TUBD1,TUBB3,TUBB4A,ACTL6B,FOXM1,TUBA8,TUBA1C,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,TUBB2B,PIK3C2A,PIK3CD,PIK3R1,PPARA,MAPK9,PTK2,ACTR6,TUBB2A,TUBB1,TUBA1A" Drug 6016_UP Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "BIN1,KCNAB2,ASCL1,MARK4,ZSCAN18,CADM3,CFLAR,BAIAP3,CACNA1D,CACNB2,CACNG1,HAP1,MTMR7,MAGI1,CACNA2D2,PHF14,MAML1,SGK2,ING4,VPS13B,CORO2B,ST3GAL6,FER,C1orf61,GAB1,GART,PCDH17,GRIA4,HPSE2,IRF8,KCNH2,KHK,MDFI,MOBP,SAMD14,NNAT,ELOVL2,TRIM68,RGS4,SH3BP2,ASAP3,RPH3A,KDM4B,PDZD2,CDK19,SYN2,SZT2,DOCK9,PSD3,AP4E1,SLC44A1,TMOD1,PARD3,LAT2,PRDM2,ITM2C" Drug 7436_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "RBM10,ABHD6,AK2,APBB2,APC,ARHGDIG,MPDZ,BAIAP3,CACNB4,NEURL1,GPR37L1,QKI,ENTPD4,FEZ1,MFAP3L,EXOG,DNM1,ATN1,HIPK3,EGFR,ENO2,MFSD10,NCALD,FHL1,B4GALNT1,ALDH1L1,MALT1,KCNH2,MBD1,SLC11A2,SETD4,PDE3B,PLCD1,STRN3,MBOAT7,PRKAR1B,WDR25,RAB3IL1,RGS12,MYH14,PAQR6,WLS,RYR1,SBF1,FRMPD1,LIMS2,IQSEC2,EXOC7,TCF7L2,PCDHA5,ZNF34,BHLHB9,EVI5,MPPE1,MVB12B,IFT88" Drug 7007_UP Artemisinin [63968-64-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ARHGDIG,BAIAP3,CA12,HAP1,FOXN3,PLEKHB1,ENTPD4,AKAP12,CRY2,CSF1R,SIPA1L1,CTNND2,RIMS3,DGKG,ELMO1,ATN1,CELSR3,ING4,FER,FUT9,ZNF44,DISC1,GLYR1,LPAR4,CNTRL,CACFD1,GRM8,HNMT,ITPKB,LSS,MAP4,GIT1,NDUFA5,NF1,PPARA,PRODH,SAMD9,RASGRF1,ZMAT4,GTDC1,FOXRED2,SBF1,SLC15A2,LIMCH1,SNCA,DOK5,ZNF423,INKA2,PHLDB1,VPS13A,PLCB1,TRIM2,TNS2,R3HDM1,PLPPR2,KAT6A" Drug 1914_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "CNTNAP1,GAS7,EIF4G3,ATP2B1,PTBP2,SRSF11,APPL1,ZFYVE16,ZNF337,TRAPPC9,SEZ6L2,SORBS3,VPS26C,TESK2,CAP2,ATP2C1,STAU2,ERAP1,INPP5K,DBF4,GLYR1,GLS,GNAS,MAP4K5,HNMT,KCNK1,NEK1,SETD4,PCMT1,PIK3C2A,CCSER2,RC3H2,PPM1B,CEP97,GTDC1,ARHGEF10L,MYH14,CCDC25,SH3GL3,SHMT2,ABLIM3,SLC11A1,KBTBD4,ELMO2,RCOR3,PEG10,RAP1GAP2,TAB2,POGZ,ZEB1,NSD1,CBX5,EIF4ENIF1,UBE3A,LRP8,DPF3" Drug 6333_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ARID1A,ADCY2,ADRA1D,BEGAIN,APC,APOC1,FGF17,ST3GAL5,CAST,KYAT1,SYNGR3,NEURL1,CACNA2D2,CHM,LHX2,ABCG1,AATK,CSF1,CSF1R,CSNK1E,SUSD5,CNTNAP2,PYGO1,EFNB3,LRRC17,FGF1,PDLIM5,HBS1L,SEPT9,SRCAP,ADAM28,GLYR1,HSD17B1,ICA1,ITIH2,KCND3,NFYA,NPTX1,PDE3B,PLCD1,PTPRE,EMID1,SBF1,HKDC1,SLC1A7,SLC2A5,SLC11A1,SLC15A2,SMARCD3,IFT122,RPGRIP1L,DOCK9,TF,RIMBP2,CDK20,SEMA3B" Drug 5842_UP Ketotifen fumarate [34580-14-8]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "MTUS1,BIN1,ANK1,CFLAR,CFAP410,CACNG1,FOXN3,CNOT8,CLU,COL9A3,SH2B1,PDE4DIP,CTNND2,DCAF4,CTIF,GIT2,CNIH3,KIAA0753,ATN1,EDN1,TUBD1,PTK2B,ST3GAL6,FGF1,SEMA4D,TRMO,ZMYND11,SYT17,GLS,GLUL,GPM6B,NR3C1,JAK2,KCND3,MIA2,NF1,POLG,PTAFR,PTPRE,FAM184A,BEND5,KHDRBS2,TCP11L1,CLIP1,MRAS,KBTBD4,SMARCA4,TMCC1,NMNAT2,NFASC,VAMP1,IQCE,DOCK9,TMEM121,TPD52,KCNAB1" Drug 604_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ASIC1,MTUS1,ANK3,APBA2,ASCL1,RAB29,CFAP410,CALB2,HAP1,PTBP2,SEPT7,CNTFR,CDC42BPB,ENTPD4,DLG3,ABCC9,SGK2,SUGP2,MBNL2,CEND1,ZNF589,FGFR1,FGR,GLS,GNG3,GRIN2C,SOX21,RNFT2,MAP4K5,HMX1,KIF2A,MMP16,NACA,CNOT4,NRGN,OMG,PHKG1,CAMKV,SLC25A23,SMIM7,PTPN13,SUSD4,RFX2,ARHGEF10L,ZFHX4,TCP11L1,PAQR6,ZFP30,KIF16B,TMCC1,RBM26,PCDHA6,CHST8,CADM1,SLC17A7,AAAS" Drug 3019_UP Furazolidone [67-45-8]; Up 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ABAT,SPARCL1,CDC42BPA,ANK3,ASPH,ATP1A2,ATP2B3,BMP7,MTMR3,CDH10,GPR37L1,LHX2,NRXN2,STOML1,DNAJB5,FAM149A,NRG2,NCOR2,CSF1,RGS6,ST8SIA3,AASS,TNK2,MTSS1L,STX2,AFF2,GAD1,ADAM28,RUNDC3A,GPR75,SOX21,HNMT,IGSF1,SCIN,KCNC1,MAPT,MMP16,NELL2,NTRK3,PLXNB1,POU6F1,RFX2,RGS4,RYR1,CCDC92,KANSL3,PALLD,VAMP1,SYT5,GPR161,TIAM1,TK2,SEZ6L,LILRA4,TRPC3,ZNF225" Drug 6000_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ASPHD1,ADRA1D,MRTFA,ASPH,ADAM23,CFLAR,LDLRAD4,BTRC,ARHGAP33,FADS2,HOMER3,CSF1R,FEZ1,CNTNAP2,DOCK4,DAPK3,GIT2,SGSM2,ATN1,CNNM1,FGFR1,FHL1,FAM49B,GLS,POLL,BTN2A1,MAP4,TAGLN3,PRKAR1B,FAM120C,ZCWPW1,ZNF821,SUPT20H,ASAP3,ABLIM3,ZNF365,BTBD7,CXXC4,WDTC1,IQSEC2,FCHO1,CEP68,PHLDB1,KAZN,MTCL1,PSD3,VIPR2,KLC2,ZFP37,ZBTB14,ZNF711,NDRG4,EMSY,SEMA3B,MVB12B,SMIM8" Drug 3936_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ASIC2,ARID1A,ADORA1,SPTBN4,LY86,NCOR2,VCAN,TOX,SPOCK2,DCT,GSDME,TRAPPC9,FAM13A,TNK2,KIAA1109,BAIAP2,FHL1,FYB1,GABRA4,POLL,GNAO1,GRM2,SYNPO,MAOB,MSI1,OGG1,OPCML,CDK14,PIK3CD,PURG,POU3F4,PTAFR,ELOVL2,MYH14,KLHDC8A,SLC30A10,STUM,RASA3,FBXO11,ST6GAL1,SLC12A4,ZHX3,ARHGAP26,LMO3,AJAP1,ABCC8,TAC3,ATP11A,DNAH7,TMOD1,AMOT,PDIA2,SLC30A3,KCNAB1,PARP11,AP3B2" Drug 2642_UP Bisoprolol fumarate; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "RALGAPA1,ADCY6,SEMA6A,AMH,FAM131A,CADM3,BAIAP3,LDLRAD4,CA4,CALB2,CAMK2B,KCNAB3,CDH8,CRLF1,CHI3L2,CHRNA4,DNAJB5,HAPLN1,DCAF4,ARHGAP24,INTS1,EXOG,EIF4G2,KIAA1109,IQCG,SIGLEC8,C1QL1,GLS,GRB10,ADAMTS13,GRM8,TLX1,KCND3,KCNN2,MITF,NOS1,CNOT4,CLDN11,CDK18,PLTP,PRPH,ATG16L1,RGS10,FNDC3A,PREX2,SMARCD3,MYH15,KDM4C,ARHGAP26,SPTAN1,MLC1,ROBO3,ICAM5,CHST5,OSBP2,VSNL1" Drug 6403_UP valdecoxib; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "DPF1,ACTN2,ADORA1,ADRA1D,KCNAB2,PDE8B,NRP2,SYNJ2,MTMR3,CHM,RAB33A,AKAP5,CRMP1,ATRNL1,ARHGAP24,DAPK1,DBT,EFNB3,NCALD,ZNF391,SPEG,APC2,ETV1,ZIC4,FGF1,GNAS,GPM6A,ADAMTS13,GRM1,GUCY1A2,HLF,ICA1,MMP16,ADAM22,MYO7A,NELL2,PDE4A,PLCL1,LRP12,ELOVL2,MYH14,TCP11L1,KCNIP1,SMPD3,PKNOX2,SLN,OGDHL,HECW1,CDK19,SPART,MAPK8IP3,ARC,AMACR,TRPM2,CA14,SLC30A3" Drug 2323_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "LTBP4,AMPD3,CDC42BPA,SEMA7A,ARRB2,MARK4,ATM,ALDH7A1,GYG2,CA12,CRLF1,CACNA2D2,QKI,NCOR2,DOCK4,DAPK3,C2CD2L,ATN1,EFNB3,EFS,CDKL3,DISC1,GRIK5,GRM7,GSTM5,ATXN2L,ITPKB,KCNN1,MMP16,GIT1,NEK1,PCDH9,PDE3B,PPP5C,RAD52,RGS12,WLS,FERMT1,FNDC3A,ZNF365,FAM214B,BTBD7,MAPKBP1,ZCCHC24,ARHGAP26,TSPYL2,MAPK8IP3,ELOVL4,NSD1,CRTC1,AP4E1,ZNF34,WIPF1,CLDND1,GDPD5,KAT6A" Drug 666_UP butirosin A from Bacillus vitellinus; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "BIN1,CDC42BPA,PPFIA1,ARNTL,EIF4G3,BMP7,FUBP1,CCNT1,SCARB1,CDH8,ADGRG1,CHRNB2,FADS2,TMEM184B,CNTN1,PREPL,CRYM,C2CD2L,DRP2,HIPK3,ELAVL4,BSCL2,FCGRT,KAT8,PRKAG2,CAMKK2,SESN1,USP19,MSL3,SLC2A6,MAN1B1,KCNJ9,KCNMA1,KCNN1,OPCML,OPRL1,PAK3,MED1,ZSCAN32,RAP1GAP,RGS3,RNASE1,ZNF821,SCG5,SLC2A5,INTS9,CAND2,SPTB,ZC4H2,SEPT8,TMOD1,METTL3,TMPRSS5,ZKSCAN5,ZNF142,WNK1" Drug 5781_DN Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ADRA1D,ALAD,APP,SEMA4G,PDE8B,ATP2A2,ALDH7A1,CFLAR,C5,CAMK2B,CDC42,QKI,CSNK1E,VCAN,CNTNAP2,SLITRK5,C2CD2L,KLHL3,KBTBD11,DLG3,TOM1,SORBS3,ING4,CDKL3,FCGRT,ANKFY1,DLL3,GAD1,ERAP1,MSL3,GNAS,SHISAL1,KHK,KIF5C,MATN3,NEK1,NF1,NFIX,CNOT4,ODF2,PAK3,PBX1,PC,PPP5C,PTPRH,BEND5,RGS10,ZNF671,FNDC3A,FAM214B,KDM4C,LHPP,TROVE2,LMF1,WNT7A,PHTF2" Drug 4073_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "LGR5,BRINP2,ADGRB2,BCHE,THSD7A,CAMK2B,RUNX1T1,USP2,NEURL1,JAM2,STOML1,PICK1,AKAP5,RCHY1,HAPLN1,CSF1R,LRIG1,MICAL2,IPCEF1,CHD5,SPOCK3,HIPK3,SIDT2,MRNIP,EFS,PRELID3A,ATP8A2,GNG4,GPD1,GRM1,SOX21,PBX1,PDE2A,PDE4A,ENPP2,MASP1,PTCH1,RGS4,EMID1,SH3BP2,SLC2A5,SLC14A1,SORCS3,SOX2,TNIK,RBM26,NPAS3,TCF4,DOCK9,SLC19A3,AP4E1,TMOD1,CHST5,CADM1,KCNAB1,PHTF2" Drug 2573_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ABAT,ANK3,PKP4,ASPH,PTCH2,N4BP2L1,BACH1,BCL2L2,SEPT7,LARGE1,CHM,CHRNB2,HOMER3,SLC4A7,HAPLN1,EDRF1,DAPK3,MAGI2,EXOG,E2F5,HIPK3,ABI2,COQ7,CDKL3,CAMKK2,GPR153,INPP5K,GPD2,GPR22,GSN,KIF3A,KCND3,LIG4,MAP4,MDM4,NEUROD1,SPATA6,PKN2,PSMD13,ZNF493,RGS3,MYH14,HSPA4L,SCG5,SLC1A7,RALYL,CRTC1,AHCYL2,RBFOX2,ZMYND8,TUBB1,LAT2,FZD3,PHTF2,NLRP3,GAN" Drug 4588_UP Vitexin [3681-93-4]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "DPF1,ADD2,AGT,LTBP4,BEGAIN,APOC1,PPP4R4,PTCH2,ATP2B3,CACNA1I,CDK5R2,MAP7,CDH8,ADGRG1,NRXN2,CREM,CRY2,CSF1,VCAN,PDE4DIP,CNIH3,PLPPR4,SPOCK3,RABGAP1L,DMPK,ATN1,DTNA,PLXNC1,TENM1,EPHB1,ZNF549,ETV1,REEP2,ST3GAL6,NSG1,GAD2,ERAP1,GPR17,DIPK1A,KCNB1,NCAM1,NF1,P2RX7,PPARA,PTPRB,CCDC40,FOXRED2,SCG5,ST6GAL1,TSNAXIP1,SOX15,HECW1,KAZN,FBXW11,TRIM2,ZNF711" Drug 4080_UP Cefadroxil [50370-12-2]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "APP,BRINP2,ATP1A2,ATP2B2,BMP7,CACNA1I,RHBDL1,CBFA2T2,KCNAB3,MAGI1,NRXN3,STOML1,FAM189A2,HAPLN1,LRIG1,MICAL2,CTNND2,CYBB,SPOCK2,DTNA,FRY,ING4,TNK2,KCNMB2,KIAA1109,CAMSAP1,AGAP2,GPR22,GRIK4,GRM7,HLF,IL12A,NEFH,NRCAM,PDE2A,SPATA6,MAPK10,RAB3IL1,ACSS3,RGS4,KLHL11,KCNIP1,RTN1,ZFP2,RASA3,SNCA,MYT1L,ZHX3,MCF2L2,PHLDB1,OBSL1,TEX15,TLR4,CADM1,FLRT2,DPF3" Drug 6049_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "SEMA6A,MRTFA,AMPH,BIN1,APAF1,GAS7,APOC1,ARHGDIG,MARK4,ASTN1,GYG2,CACNG1,THSD7A,KALRN,CHRNA4,PLCH2,RIMS3,GSDME,TUBB4A,CORO2B,KIAA1109,HPCAL4,DLL3,GAD1,CACFD1,NR3C1,GRM8,HTR5A,IRF8,ITGA7,ITIH2,KCNMA1,KIF5A,SAMD14,NPY,P2RX7,TRHDE,NECAB2,PPARA,RELN,ELOVL2,RGS12,KCTD17,SLC2A5,KANSL3,CCDC88A,LIMCH1,WDTC1,JMJD6,TGFBR3,HEY1,LAT2,SLC30A3,STMN4,SLC17A7,ADAMTSL3" Drug 5474_DN Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "SLC12A5,MTUS1,APBB2,EPB41L5,APP,CASK,CAPRIN2,MPDZ,C5,CAMK2G,SLC25A14,LRRFIP1,MAGI1,BAG4,PPP6R2,MFAP3L,MED24,DLG3,EXOG,DSCAM,RCAN1,SORBS3,EPB41L2,ANKMY1,GMPR2,F3,TAOK3,CINP,GPD2,INPP5B,KHK,MITF,MPP2,LYRM9,NACA,SLC11A2,RETREG1,MBOAT7,RGS12,TCP11L1,FOXRED2,ZNF821,SMTN,BTBD7,SLC22A4,UNC5B,CDK19,NXT2,ARHGEF9,FAM208A,TK2,NPL,ZNF384,TRIO,ZNF74,HPS4" Drug 3584_UP Mesalamine [89-57-6]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ABHD6,ADRA1D,SRPX,APLP1,SEMA4G,CDK13,ATM,CFLAR,MTMR2,CACNG1,ARHGEF2,CDH10,RCBTB2,LHX2,QKI,CREM,CRMP1,VCAN,TBC1D5,RIMS3,BRINP1,ST8SIA3,EFNA3,EFNB3,EGFR,AASS,EN2,SPEG,RRAGB,ANKFY1,TRAF3IP2,TMEM8B,GATM,GLYR1,GNG3,GRM1,GSN,GSTM5,VSIG4,DHX35,ADAM22,NTRK3,PRKAR1B,MAPK10,SALL1,ASIC4,CNKSR2,ABLIM3,POGZ,PLCB1,ARC,PSD3,BEX4,PARD3,NT5M,GDPD5" Drug 4088_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ASIC1,GAS7,PDE8B,RIPK1,KIF1A,SOCS6,RAB28,RAB26,CNTFR,CRMP1,TENM4,PDE4DIP,EDRF1,DAPK3,PLPPR4,SGSM2,KBTBD11,SIDT2,CELSR3,LRRC23,ETV1,EZH1,GAD1,ZMYND11,GLYR1,GPM6B,ICA1,SHISAL1,IL6ST,KIFC3,MATN3,MOBP,OPCML,PDE4D,SERPINI1,RETREG1,PLXNB1,PPP5C,CNTLN,ZSCAN2,ATG16L1,FAM184A,ZCWPW1,ZNF821,ANKRD6,SLC4A3,LIMCH1,WDTC1,EMC1,SRPK2,CEP68,ASTN2,TRIM2,NSD2,EMSY,FZD3" Drug 4086_DN Trimethadione [127-48-0]; Down 200; 28uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ASIC1,MTUS1,CDC42BPA,AQP4,PPP4R4,NRP2,SYNJ1,SYNJ2,BTRC,ARHGEF2,FOXN3,LHX2,DNAJB5,LY86,CNTFR,WHRN,NCOR2,CSNK1E,CNTNAP2,EDRF1,RIMS3,BRINP1,MFAP3L,ELN,MTSS1L,ETV1,EZH1,FGFR1,EFCAB2,CGREF1,CSPG5,GAB1,SEPT9,GRIK2,ICA1,KCNMA1,ZNF862,MYT1,NOVA2,SLC11A2,OGG1,PPP5C,MAPK7,MAPK8,SAMD9,RALGDS,ATG16L1,ZCWPW1,RGS10,SLC4A3,SNCA,DDN,JMJD6,IQCE,OSBP2,EVI5" Drug 5761_DN Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "RALGAPA1,NME5,ALK,KCNAB2,CDC14B,ARNTL,CFLAR,MYRF,CFAP410,CA8,LARGE1,FOXN3,HINFP,PDE4DIP,PPP6R2,MFAP3L,RCAN1,EIF4G2,EN2,PLEKHO1,COQ7,EPHA5,FAM49B,ZNF276,GNG4,KCNH2,MAPT,MDFI,SCAMP5,SETD4,PC,MAPK7,GRAMD1C,GAL3ST4,RGS7,PAQR6,SUPT20H,AMBRA1,SLC14A1,CDK5RAP2,SNCA,TNIK,EMC1,ARHGAP26,ZBTB43,SS18,TCF4,TNS2,GPR161,TNS1,TRIO,ZMYND8,VGF,WIPF1,XRCC4,RNF146" Drug 5774_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "ADCY6,PPFIA3,APP,MARCH3,CDK5R1,CFAP410,CAMK2B,ARHGEF1,LRRFIP1,RAB28,NMT2,DNAJB5,SLC4A8,CSF1,DCAF4,RIMS3,DAPK3,CNIH3,C2CD2L,FEM1B,SUGP2,MRNIP,PLEKHO1,SPEG,ETV1,C1QL1,GLS,GNG4,GPM6B,GPR19,MAPT,MDFI,GIT1,NPR2,NUMA1,PBX1,NLE1,PTPRH,FAM120C,RAB3A,RALGDS,FAT4,FAM184A,BEND5,TTLL7,ZNF821,ST6GAL1,KDM4D,KDM4C,ELOVL4,COBL,ZBTB14,NT5M,PLSCR4,KAT6A,GAN" Drug 4533_UP Homosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "SYT13,CDK13,BCL2L2,CFLAR,ST3GAL5,BAIAP3,BTRC,ARHGAP33,CHGA,SOCS6,CNTN1,NRG2,CPS1,SH2B1,VCAN,CDON,DTNA,HIPK3,EGFR,IRAK4,ING4,FGF1,FLT1,FYB1,NEU3,GNAL,GPD2,LILRA2,ADAMTS13,KCNJ5,KIF5C,KIT,MATN3,NTRK2,PDE3B,PFKFB2,LRRN3,MAPK8,GRAMD1C,RAD52,RASGRF1,RET,RAVER2,ROM1,RASA3,KANSL3,SLC20A2,ZNF415,RBM34,ZNF423,BEX1,RBM26,SYT11,KIAA1107,UBE3A,KCNAB1" Drug 2141_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "SRPX,CDC42BPA,APAF1,AQP4,SEMA4G,KIF1A,FUBP1,MYRF,BTRC,MAP7,SYNGR3,CLU,DNAJB5,SULT4A1,SIPA1L1,DCT,ST8SIA3,EEF1A2,TNK2,C3orf18,VPS13B,KIAA1109,HPCAL4,NBEA,GPR153,SIGLEC8,GPD2,GSN,ICA1,IL6ST,MSR1,NELL2,NF1,NUMA1,PMP22,GRAMD1C,SYTL2,PTPRN2,RIPOR1,SEC61A2,SBF1,CCDC92,ANKRD6,RPH3A,SLC20A2,ZHX3,CAMSAP2,TNS2,TEX15,FAM155A,UBE3A,LMF1,KLC2,ZFP37,NAV2,SLC17A7" Drug 6030_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.81E-06 3.34E-01 1.21E-04 1.38E-03 56 200 "DPF1,C1QTNF1,SYT13,OGT,PDE8B,MARK4,AZGP1,ADGRB3,KALRN,ADGRG1,ASIC3,MFAP3L,SPOCK3,ATN1,USH1C,ELN,HSD17B14,CEND1,NRN1,FGF13,FGFR1,FHL1,ADAM28,PRUNE2,GPM6A,GRK4,RAPGEF4,GRIK1,GRM7,SMAD9,MAOB,MMP17,TAGLN3,NPY,NOVA1,PDE4A,CAMKV,PLCD1,MINDY2,CEP41,MASP1,GAL3ST4,RGS4,FRMPD1,PKNOX2,SLC11A1,SNCA,ZNF415,ARHGAP26,ATP10B,ACSBG1,SYT5,OBSL1,ZFPM2,R3HDM1,SEZ6L" Drug 6987_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.84E-06 3.35E-01 1.22E-04 1.39E-03 53 186 "BRAP,EPB41L5,GAS7,CCKBR,REPS2,FEZ1,PDE4DIP,DBT,SGSM2,MED12,TRAPPC9,SHANK1,SIDT2,ING4,TESK2,DPYSL4,MALT1,GLYR1,GLS,TDRKH,STON1,HNMT,HPCA,MAP4,MAPT,MBD1,MITF,MXI1,LYRM9,ZNF862,NUMA1,SERPINI1,NECAB2,MAPK7,RAB3IL1,GTDC1,RFX3,RGS3,PAQR6,SLC6A8,COA1,TSNAXIP1,DOK5,KDM3A,TROVE2,VAMP1,TACC1,SEMA4A,TCF7L2,TK2,CABIN1,TRPC1,ZNF23" Drug CID004369171 Al 6629 Stitch 6.90E-06 3.38E-01 1.23E-04 1.40E-03 48 163 "CA4,CALB1,CALB2,NGB,NOG,NUMBL,CNTFR,CRY2,SLC32A1,SV2B,ELAVL3,OLIG2,GPHN,ADGRV1,PPP1R1B,FGFR1,TBR1,GAD1,GAD2,GFAP,GRIA1,GRIA4,GRIK1,KCNA4,KCNA6,MYO7A,NOS1,NPY,NPPA,NTRK2,OPA1,P2RX7,PAX6,PRPH,RGR,RLBP1,ROM1,SLC6A1,SLC6A11,SLC15A2,SST,RGL1,SYP,ZFP91,RGMB,TRPC1,RGMA,SLC17A6" Drug CID000001217 3HPG Stitch 7.00E-06 3.43E-01 1.25E-04 1.42E-03 11 17 "GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug ctd:D010656 Phenylephrine CTD 7.05E-06 3.46E-01 1.26E-04 1.43E-03 117 506 "ACADM,ADCY5,GALNT13,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,PLA2G6,PKP4,DGKZ,CADPS,ATP2A2,BMP7,C5,CA4,CAMK2A,CAMK2D,RUNX1T1,CCNT1,CDH2,CLU,DNAJB5,COX4I1,CREM,VCAN,CTH,TOX,DAPK1,RCAN1,ABCC9,E2F5,EDN1,EDNRA,EDNRB,EGFR,CALCRL,ENO2,NCALD,FGF12,FHL1,FLT1,MYOZ2,RND1,GNAS,GPM6A,RAPGEF4,NR3C1,WIF1,ELOVL5,IGF1,KCND2,KCND3,KCNH2,STMN1,LIMS1,MAOB,MEF2C,MYH6,MYH7,NODAL,NPY,NPPA,PDE1A,PDE4B,PKD1,PKM,ST8SIA5,PLCD1,EPB41L4B,PPARA,PPP3CB,PRKCB,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,MAPK10,MASP1,PTHLH,REV3L,RGS3,RGS4,MYH14,TMEM206,KCNIP2,S100B,SEMA6D,SOX6,SGK1,SLC1A3,SLC4A3,SLC8A1,SLC12A2,CXXC4,SPP1,ADHFE1,PLCB1,TAC1,TACR1,TRIM2,ARHGEF12,ZFPM2,ITGB3BP,THRA,HEY2,CABIN1,RASD2,TPM2,TRPC1,TRPC3,TSC2,UCHL1,HRASLS" Drug CID000004920 17-isoprogesterone Stitch 7.08E-06 3.47E-01 1.26E-04 1.43E-03 239 1171 "ACTN1,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,AGT,OSBPL6,OSBPL8,SPARCL1,AMH,BIN1,ANXA7,APAF1,APOC1,APOC2,AQP4,ARHGDIA,ARNTL,CDK13,NCOA1,SLC2A11,BCL2L2,BID,BMPR1B,LDLRAD4,NGB,CH25H,MAP7,PRC1,SLC5A11,AIFM1,LRBA,LGI1,CDR1,NOG,CRLF1,CHGA,CHGB,CHRM1,CHRNA4,CHRNB2,CLU,FADS2,ABCG2,COL4A5,COL11A2,TBPL1,NCOR1,NCOR2,ABCG1,CSF1,CSF1R,SIPA1L1,GREB1,DBI,CNIH3,GSDME,NTM,EDN1,EGFR,EIF5,IRAK4,TUBD1,ERBB2,ERBB4,ETV1,F3,TUBB3,TUBB4A,FDFT1,PPP1R1B,POLR1B,PRKAG2,AGAP3,FLT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,MTHFD2,TUBA8,MSTN,GDF9,CYP46A1,GFAP,GFER,GGT7,GGT5,GHR,PPARGC1A,LYVE1,GJB1,CRCP,STARD3,LOXL3,GNAS,GPR12,GPR17,GPER1,TUBA1C,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,ADAMTS8,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,FAM107A,HBA1,TNFAIP8L3,HPSE2,HMGCR,HP,HPR,HSD17B1,HSP90AA1,HTR2A,IGF1,IGFBP1,IL6ST,TUBB2B,ITGA7,KCNK3,KCNMA1,MAG,MAOB,MAT2A,MBP,MMP16,MMP17,MOBP,NEFH,NODAL,NOS1,NPY,NPPA,NPTX2,OMG,OPRL1,OXTR,PCDHGC3,PDGFRA,PDYN,PENK,CDK14,ABCB1,PLP1,PMP2,PMP22,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,KLK6,PTCH1,PTHLH,PTPN13,PPP2R3C,PID1,ROGDI,ZNF532,PTGR2,RPS20,HUNK,CLIP1,SAFB,MAPK12,FBXO11,FNDC3A,SYBU,SLC2A5,SLC15A2,PDZD2,SOX11,SPP1,PEG10,SST,LARP4,ERBIN,APOM,SYP,TAC1,CUX2,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,TF,LEFTY2,THRA,TIMP4,TLL2,RIMBP2,NR2C2,TRH,TTPA,TUBB2A,SGK3,TUBB1,UBC,UBE2H,UBTF,USP1,CLIP2,XRCC4,ZBTB16,SMARCAD1,TUBA1A,SCG2,HPS4,RTN4,NETO1,AP3B2" Drug 1951_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A" Broad Institute CMAP Up 7.17E-06 3.52E-01 1.28E-04 1.45E-03 51 177 "ACLY,ABHD6,ADRB2,KIDINS220,SHROOM2,ARNTL,ATP2B1,HIP1R,SPAG9,CLU,AKAP12,CTH,KIAA0513,C2CD2L,ANKRD46,EPS8,F3,TAOK3,BAIAP2,NBEA,FYN,GLS,RAB40B,GPR37,GUCY1B1,HMGCR,KIF5C,MEF2C,AFF1,MYO6,PCDH9,RETREG1,PLCD1,SMOX,RAB3A,RGS4,NUDT11,SBF1,SH3GL3,PALLD,KDM4B,DOP1A,ZCCHC24,RGL1,SYT1,AGTPBP1,TIAM1,HEY1,TNS1,DNAJC12,PLSCR4" Drug 497_UP 2-propylpentanoic acid; Up 200; 1000uM; ssMCF7; HG-U133A Broad Institute CMAP Up 7.25E-06 3.55E-01 1.29E-04 1.46E-03 54 191 "ABHD6,NDRG2,LTBP4,MARK4,ADGRB2,MPDZ,SYNJ1,SGCE,RAB29,BAIAP3,CAMK2A,LHX2,RAB28,SLC4A7,ARHGEF10,ECE2,C2CD2L,EFNA3,RGS17,ENO2,EPHB1,STX2,FHL1,DPYSL4,NSG1,FYN,B4GALNT1,CYP46A1,KHK,KIF5C,MAPT,NRGN,PLCD1,SUSD4,RGS3,TTLL7,PPM1E,ASAP3,FAM214B,SLC9A5,SNAP25,ZCCHC24,NMNAT2,TSPYL2,SPART,FCHO1,EXOC7,WSCD1,ATP13A2,DNAJC12,MICAL1,REEP1,MAP3K12,SLC17A7" Drug 6644_DN Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.25E-06 3.55E-01 1.29E-04 1.46E-03 54 191 "ADCY6,APBB2,APP,MARK4,SYNJ2,CCNT1,WHRN,HINFP,VCAN,PDE4DIP,CNTNAP2,FAM169A,DAPK3,GIT2,KIAA0753,SMG7,EFNA3,FAM13A,EIF4G1,PLEKHO1,EPHA5,ETV1,ZNF589,KIAA1109,SPIN1,STON1,HLF,LSS,MAP4,MAPT,MMP16,MX1,NEK1,NF1,NUMA1,SSH1,PIK3R1,PLCD1,TNPO2,MED1,MAPK8,RALGDS,PEX26,KDM4B,SPTAN1,EHBP1,KAT6B,TRIO,ZBTB38,WNK1,SNX27,WIPF2,KAT6A,AAAS" Drug 4614_UP Colchicine [64-86-8]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.25E-06 3.55E-01 1.29E-04 1.46E-03 54 191 "ACTN2,AK2,LTBP4,MRTFA,DOC2A,ASCL1,NOL4,CACNA1G,CACNB2,CACNG1,FOXN3,NRG2,AKAP12,CHD5,DRP2,ABCC9,SIDT2,CALCRL,RASGRP2,SORBS1,PRELID3A,B3GAT1,DOT1L,GNG4,FERMT2,SPACA9,IL6ST,KCNH1,KCNJ5,MIA2,AFF1,NEFM,PDE1C,RETREG1,NLE1,EMID1,FUZ,NLGN1,SLC11A1,SLCO1A2,SOX15,ZNF423,ARHGAP26,RAP1GAP2,DDN,ATP10B,ELOVL4,PHLDB1,DAAM2,TRIO,UBE3A,VIPR2,WNT7A,NAV3" Drug 4168_DN Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.25E-06 3.55E-01 1.29E-04 1.46E-03 54 191 "C1QTNF3,EP400,ATM,BACH1,SOCS6,NMT2,QKI,SLC4A7,PREPL,CRY2,MICAL2,FAM169A,DZIP3,GPRASP1,ZFYVE16,ZNF337,RIMS3,DBT,SIDT2,VPS13B,EZH1,PRKAG2,ANKFY1,GLYR1,PCLO,KCNJ3,MDM4,AFF1,CNOT4,CCSER2,RETREG1,POLG,VPS13C,RIPOR1,CLIP1,SFPQ,PEX26,FNBP1,ZHX3,CDK19,TROVE2,SYNE2,PLCB1,TACC1,ANKRD12,PSD3,ZNF106,CBX5,RBFOX2,TRPS1,ZMYND8,VGF,VLDLR,ST7" Drug 4647_DN Butylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.25E-06 3.55E-01 1.29E-04 1.46E-03 54 191 "ADCY6,PPFIA1,APOC1,ARRB2,ASPH,ATP2A2,SYNJ2,CANX,SPAG9,CHM,TAOK2,TPP1,QKI,PDE4DIP,CNTNAP2,ARHGEF4,DCAF4,GPRASP1,DBT,KIAA0753,SMG7,FEM1B,EGFR,ANKMY1,FGFR1,ANKFY1,GART,PRRC2B,GPD2,KIF5C,LIG4,NDP,NFYA,NUMA1,PAK3,PBX1,PLEC,TMEM231,TRAPPC13,SAFB,ZKSCAN3,SMARCA4,TNIK,ARHGEF9,TCF4,TRIM2,TK2,CABIN1,TRIO,SSBP2,HIRA,UBTF,NSD2,XRCC4" Drug CID000010101 ketobemidone Stitch 7.33E-06 3.59E-01 1.30E-04 1.48E-03 15 29 "PNMA2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 1078_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ST3GAL5,RAB29,WASF1,NMT2,RAB26,SLC4A7,SOCS5,USP6NL,RIMS3,DBN1,PARD6A,RCAN1,GNE,SIDT2,EFNA3,EFNB3,EML1,STX2,ARMCX1,BAIAP2,SEC23B,GPR153,CSPG5,FYN,SYT17,GLS,KCNMB4,HSF2,DIPK1A,KIF5C,MAP4,MAPT,MIA2,PFKFB3,STRN3,MBOAT7,PRKACB,PRKAR1B,LRRC49,PTPN13,SUSD4,ARID4A,ATXN1,SMTN,SMARCC2,ZBTB43,ELOVL4,STXBP1,MTCL1,TRIM2,BHLHB9,BEX4,REEP1,ZNF184,EVI5" Drug 3314_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "KIAA1324,LTBP4,CDC14B,ATM,CACNA1G,USP2,CBFA2T2,NEURL1,STOML1,WHRN,CSF1,JAKMIP2,DMPK,SGK2,DMTN,STX2,BAIAP2,FOXG1,C1orf61,SRCAP,USP19,NR3C1,ATXN2L,ICA1,IL6ST,ITGAM,KCNMA1,MAP4,TAGLN3,MYT1,NDUFA5,NTRK2,SNTG1,NECAB2,RAB3IL1,RGS12,MYH14,KCNIP1,PPP1R9A,FRMPD1,LIMCH1,TSNAXIP1,SOX10,HECW1,ST5,INKA2,ARC,ROBO3,WSCD1,PCDHGA10,SEZ6L,FLRT2,SLC30A3,DNALI1,SSPN" Drug 5455_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ADRA1D,PDE8B,ATM,KIF1A,BMP7,SCAPER,BAIAP3,CBFA2T2,CLGN,NMT2,MICAL2,SIPA1L1,GREB1,MAML1,DMTN,NCALD,FGFR1,FHL1,IP6K2,OGA,GPM6B,GPER1,CNTRL,IL6ST,KCNJ3,MAPT,ADAM22,NDUFA5,NF1,NLE1,LRP12,MBOAT7,PRODH,PEX5,RAD52,RGS12,SBF1,BTBD7,SLN,SMARCA4,ZSWIM8,INKA2,TTBK2,PLCB1,ATP11A,TRIM2,PSD3,BHLHB9,PARD3,CABIN1,KCNK12,SPHK2,UPF3A,WNK1,KAT6A" Drug 3253_UP Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ABHD6,NDRG2,ADORA2A,C1QTNF3,LTBP4,TRMT9B,RGS20,SYNJ1,B4GALT6,TMEM59L,PICK1,RIMS2,HDAC9,RIMS3,DRD1,EDN1,HEYL,EGFR,SEMA4D,FYB1,GCNT2,GRIN1,INPP5B,KCNH2,MDM4,GIT1,ZNF862,NF1,NTRK2,PLCD1,GRAMD1C,DCHS2,CNNM2,PEX5,ZFHX4,TCP11L1,SH3BP2,PPM1E,ASAP3,BCAN,TROVE2,PHLDB1,ARC,TCF7L2,SYNE1,SLC19A3,TP53BP1,WIPF1,SPHK2,SLC30A3,NT5M,GDPD5,SLC17A7,KAT6A,NLRP3" Drug 3613_DN Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AP2A2,NME5,LTBP4,DOC2A,APC,SLC4A4,SGCE,BTRC,NEURL1,CNTFR,RCHY1,CNTNAP2,GREB1,HP1BP3,DTNA,HIPK3,MRNIP,EPB41L1,FGF13,FOXG1,ALDH1L1,GSN,HSF2,INPP1,INPP5B,JAK2,KCNJ3,KIF2A,MATN3,BCO1,SERPINI1,NLE1,PLCD1,LRP12,MAPK8,RAB3IL1,CARF,RPS6KA2,SBF1,SHANK2,ZKSCAN3,SEMA4A,EXOC7,IQCE,SIN3B,AP4E1,TGFBR3,SLC44A1,VGF,MICAL1,LMF1,ZIC3,GDPD5,ITM2C,PHTF2" Drug 3083_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "MRTFA,TRMT9B,MPDZ,CDK5R1,CACNA1I,BTRC,INA,RAB33A,NMT2,RAB26,ABI3BP,MYRIP,ABCG1,USP6NL,DAPK3,SPOCK2,OLIG2,MTSS1L,ETV1,ATP8A1,C1orf61,HPGDS,PRUNE2,PCLO,ELOVL5,MAP4,MEF2C,MID1,NCAM1,PDE1B,POU6F1,PRPH,BCAS3,RIPOR1,RAD52,EMID1,CNKSR2,PALLD,RAP1GAP2,SEPT8,ATP11A,TACR1,WSCD1,TCF7,SZT2,OBSL1,SLC35G2,TMOD1,TRO,TRPC1,VAV2,LMF1,MAP3K12,NAV2,FZD3" Drug 7167_UP Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NDRG2,KIDINS220,ADGRF5,DOC2A,APOC1,MARK4,CAPRIN2,ATM,CADM3,RGS11,NRP2,CACNB4,CHRNB2,QKI,AKAP12,NCOR1,SOCS5,PDE4DIP,PPP6R2,EDRF1,DAPK3,LYPD1,EGR3,AASS,ING4,SEMA4D,FYB1,SRCAP,TDRKH,RAPGEF1,PRDM5,KLF12,KCNN1,MPP2,MSR1,NPTX1,SLC11A2,NTRK3,PGAM2,PRPH,KHDRBS2,RPS6KA2,ZNF365,PPP4R3A,EPN2,SLC8A1,ZCCHC24,INKA2,MAPK8IP3,PLCB1,DOCK9,TPD52,ZMYND8,WNK1,SLC30A4" Drug 3563_UP Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "RALGAPA1,ADRA1D,AP2A2,BIN1,CDC42BPA,KCNAB2,CDC14B,ATM,ATP1A3,CAST,ARHGEF1,DLGAP1,PLEKHB1,TAOK2,EPS15L1,PHF14,INTS1,MYEF2,TMCC2,CNNM1,EFNA3,EGR3,TENM1,ELAVL2,HSD17B14,PTK2B,KHDRBS3,INPP5K,RND1,GNAS,ATF7,ADAMTS13,PTGDR2,KCNJ5,MAN2A2,ADAM22,NF1,NPPA,OPRL1,PIK3CD,POLG,PPP2R2B,PTPRH,C1orf54,RPS6KA2,MRAS,ZNF365,SLN,COA1,SNCA,ZC4H2,ARC,ROBO3,HEY2,WNK1" Drug 6884_DN AG-012559 [369370-06-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ASPHD1,SEMA7A,APBB2,APP,CFAP410,SOCS6,HOMER3,SH2B1,CSF1R,PDE4DIP,PHF14,RIPOR2,ZFYVE16,SMG7,RCAN1,DTNB,FEM1B,SIDT2,ING4,DMTN,FGF1,TRAF3IP2,TMEM8B,GLS,NR3C1,HNMT,SHISAL1,INPP5B,KIF2A,MKLN1,CCSER2,C19orf57,PRKAR1B,RGS12,TTLL7,TRAPPC13,ZNF821,ITSN1,FBXO11,FAM214B,TMCC1,KDM4B,ZHX3,ASTN2,SATB2,TRIM2,AHCYL2,ZNF34,TK2,LMF1,XRCC4,ZNF32,REEP1,SLC30A4,DPF3" Drug 3992_UP Phenacetin [62-44-2]; Up 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ADD2,MTUS1,ANK2,CDK13,ADAM23,AZGP1,NRP2,CACNA1G,BAIAP3,VAX2,LY86,CABP1,TCEAL2,TOX,C2CD2L,SV2B,TRAPPC9,EDNRA,HIPK3,CELSR3,KIAA1109,DCTN2,OGA,GAB1,GATM,NEU3,GNAO1,RAPGEF4,GRIK1,ADAMTS8,KIT,LSS,MDM4,NCAM1,NTRK2,GPR88,PHKG1,ACSS3,C1orf54,RASGRF1,BEND5,RFX2,SLC1A2,SLC4A3,PKNOX2,SLC11A1,HECW1,NFASC,ATP11A,MCF2L,OBSL1,PCDHA5,SEZ6L,TPM1,PHTF2" Drug 7335_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ABHD6,NDRG2,C1QTNF3,SRPX,LTBP4,MRTFA,APBB2,SLC2A11,CFLAR,RAB29,USP2,SRSF11,ZFYVE9,FADS2,QKI,HOMER3,ARHGEF6,GREB1,SNPH,GIT2,RUSC2,MBNL2,PLXNC1,OLIG2,LRRC23,MTSS1L,STX2,ERCC2,PRELID3A,SIGLEC8,SRCAP,TXNL4A,TDRKH,GRIK5,ELOVL5,DHX35,IL6ST,KIF5A,MITF,NF1,NUMA1,NLE1,SLC25A23,ATG16L1,RFX2,RGS12,FBXW7,TRAPPC13,SLC1A7,ZCCHC24,DMXL2,TMOD1,MICAL1,SLC17A7,JPH3" Drug 3816_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NME5,ATP1A3,ALDH7A1,NRP2,BMP7,IL33,CAMK2B,ARHGAP33,PLEKHB1,TAOK2,DNAJB5,SLC4A8,IFFO1,NRG2,CRMP1,CRY2,CSF1,RIMS2,ARHGAP24,MFAP3L,ING4,TNK2,SPEG,PRELID3A,CGREF1,OGA,B4GALNT1,TMEM8B,GNG3,GPM6A,GPM6B,TDRKH,GPR17,ICA1,ITIH2,LAMA2,SCAMP5,TAGLN3,ZNF862,NOS1,PTN,PTPRB,RAB3IL1,RGS10,NTNG1,RPH3A,SNCA,MAPK8IP3,SMG6,RPGRIP1L,DOCK9,HIRA,PLPPR2,ZNF74,PRDM2" Drug 7337_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "PLA2G6,TRMT9B,APBB2,APLP1,FAM131A,PPP4R4,ARHGDIG,MARK4,ASPH,CADM3,ADGRB2,LDLRAD4,DNAJB5,ABCG1,FAM169A,SNPH,PARD6A,DSCAM,PHF20L1,MRNIP,ERCC2,KIAA1109,ZNF44,MALT1,TDRKH,IL6ST,CNOT4,NPTX1,NTRK3,PCDHGC3,DUSP26,LRP12,MAPK7,PTHLH,ZSCAN32,FAM120C,RAB3IL1,KHDRBS2,RGS12,ZNF821,PREX2,SMTN,BTBD7,SMARCC2,SNAP25,SNCA,RBM26,PLCB1,RUNDC3B,FAM155A,FLRT2,FLRT1,VAV2,VLDLR,SSPN" Drug 5910_UP estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "BIN1,ZSCAN18,CDK5R2,CACNB2,CAMK2B,SCARB1,CHRNA4,EPS15L1,TPP1,CABP1,AKAP5,ENTPD4,MFAP3L,TNK2,MRNIP,RGS17,VPS13B,FGF12,FOXG1,SORBS1,ALDH1L1,GFER,C1QL1,GNAS,GNG4,GRIA4,GRIK2,SPACA9,GUCY1B1,VWA5A,MAN2A2,CNOT4,NPTX1,PCBP3,NTRK2,PDE4B,MAPK8,RASGRF1,ZMAT4,RASA3,FRMPD1,AMBRA1,PKNOX2,SLCO1A2,SNCA,ARC,ASTN2,SYT5,EXOC7,CHST8,GPR161,TRIO,TRO,ZNF74,PARP6" Drug 3167_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ABHD6,ADCY6,LTBP4,TRMT9B,CDC42BPA,CDC14B,MARK4,CDK5R1,CACNA1D,CAMK2G,KYAT1,SRSF11,PLEKHB1,FAM189A2,HOMER3,AKAP7,BAG4,CRY2,FEZ1,PDE4DIP,SDC3,GIT2,DMTN,FGFR1,PRELID3A,GPR153,ZNF44,USP19,POLL,GRB10,NR3C1,MUM1,HNMT,NF1,PDE3B,CAMKV,PLEC,RGS10,EMID1,ZNF821,PEX26,KIF13A,WDTC1,ZSWIM8,MAPK8IP3,VAMP1,ATP11A,SEMA4A,CHST8,ZNF34,ZKSCAN5,HIRA,LMF1,WNK1,UBE3B" Drug 6303_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ARID1A,ADRA1D,KIDINS220,PLA2G6,ALAD,ASTN1,ATP6V0A1,NRP2,CACNA1G,CALB2,CAMK2B,CDH10,ARHGAP33,ADGRG1,CHRNB2,CRMP1,AATK,RGS6,CHRDL1,CDON,MRNIP,STX2,ETV1,RRAGB,BAIAP2,AFF2,FYB1,ZNF44,TRAF3IP2,ERAP1,SIGLEC8,GCNT2,USP19,LPAR4,ATXN2L,LIG4,MT1M,MYO7A,NOVA1,PENK,PPARA,SAMD9,RAB3IL1,CCDC40,RGS10,ATXN1,RPH3A,SNAP25,KIAA1107,PCDHGA10,ARHGEF12,SEZ6L,TRO,ZNF74,KCNAB1" Drug 2431_DN Melatonin [73-31-4]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "RALGAPA1,ARID1A,BCAR3,MRTFA,BIN1,PPFIA4,APAF1,APP,SCAPER,LDLRAD4,CAPN3,CCNT1,ARHGEF1,RAB33A,ARMC8,CREM,CRY2,ABCG1,CSNK1E,SLITRK5,DNM2,DTNA,EFNB3,CELSR3,C3orf18,FOXG1,INPP5K,ALDH1L1,GLS,SPACA9,NCKAP1L,MAP4,MYO7A,CNOT4,NPR2,CNTLN,PTCH1,TMEM231,CEP97,ZCWPW1,MRAS,SH3BP2,SLC20A2,ZKSCAN3,SNCA,IZUMO4,EMC1,ADGRL3,CHST8,ICAM5,PIK3R5,TPD52,HSPBP1,LMF1,SPHK2" Drug 3705_DN Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "MTUS1,ADGRF5,PKP4,APC,APOC1,APP,ADGRB2,ST3GAL5,PLAA,ABCG1,SDC3,CTH,HDAC9,TOX,KIAA0513,DAPK3,CHRDL1,RCAN1,LPAR6,ING4,COQ7,DENND4A,RRAGB,FGF1,PDLIM5,TRAF3IP2,GNAS,GUCY1B1,HSF2,INPP5B,JAK2,LIG4,MBNL1,TAGLN3,MX1,NUMA1,LRP12,SAMD9,RAB3A,KCTD17,OGDHL,TROVE2,COLGALT2,ARHGEF9,KIAA1107,TBCEL,TCF4,TRIM2,SZT2,TRIO,SSBP2,UGT8,TFIP11,MVB12B,SMIM8" Drug 4760_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NDRG3,NDRG2,KIDINS220,DOC2A,AMPD3,BIN1,MARK4,ALDH7A1,GYG2,BTRC,CA4,RCBTB2,LHX2,PLAA,CNTNAP2,RIMS2,EDRF1,NOS1AP,DBT,ARMCX2,MFAP3L,RABGAP1L,GNE,ING4,F3,DLC1,ST3GAL6,KAT8,FGFR1,AFF2,PDLIM5,TRAF3IP2,HBS1L,IL6ST,KCNJ3,KCNMA1,LIG4,MEF2C,KITLG,MMP16,NFYA,NPTX1,STRN3,GRAMD1C,SAMD9,KCTD17,SELL,SGK1,DOP1A,KAZN,TNS2,CHST8,TRIO,ZNF45,PHTF2" Drug 4370_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AGT,BIN1,CDC42BPA,APC,GAS7,APOC1,CACNG1,ARHGEF2,JAM2,CLTB,SULT4A1,DCT,TRAPPC9,ELAVL3,REEP2,FABP7,FHL1,CSPG5,GABRG2,GNAO1,GPM6B,GRIN2C,GRM1,GUCY1A2,KCNJ5,LMO1,AFF1,TAGLN3,NPR2,OGG1,P2RX7,PCDHGC3,PCSK1,PIK3CD,PLCB2,STRN3,RAD52,RFX2,STUM,SLC1A3,SLC1A7,SLC2A5,SLC11A1,MYO16,SOX2,AJAP1,SYT11,PLCB1,DICER1,SEZ6L,AMOT,UCHL1,LAT2,EVI5,SSPN" Drug 3742_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "DPF1,ADCY2,LTBP4,BEGAIN,RASL11B,SLC2A11,NRP2,BAIAP3,FOXN3,TAOK2,RAB28,VAX2,HOMER3,AATK,PHF14,DAPK3,DTNA,ST8SIA3,EGFR,EFS,BAIAP2,RND1,TDRKH,GPR19,GRM1,IL1RAPL1,ICA1,ITPKA,KIFC3,MATN3,NNAT,NPTX1,PDE4D,PDGFRA,PGAM2,PLXNB1,C19orf57,PRKAR1B,SYTL2,ELOVL2,RAD52,KLHDC8A,SAFB,SH3BP2,FNDC3A,KIF21B,NFASC,ATP10B,SS18,ARC,ASTN2,TBL1X,TRIM2,STMN4,NUP214" Drug 3351_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ASPHD1,ASIC1,MRTFA,CDC42BPA,KCNAB2,APLP1,APP,CDC14B,PDE8B,ASPH,BMP7,MTMR3,ADGRG1,WHRN,NCOR1,CSF1,ARMCX2,EGFR,LRRC23,STX2,FAM49B,GLS,GNG3,STON1,CNTRL,KCNJ5,SMAD1,TM6SF1,MPP2,NF1,NUMA1,PLCD1,PPP2R5C,PRKAR1B,MAPK10,GRAMD1C,PTN,PEX5,RAD52,TCP11L1,FAM214B,EMC1,IQSEC2,SPART,TROVE2,MAPK8IP3,TCF7L2,THRA,RUNDC3B,VIPR2,WIPF1,KCNK12,REEP1,SYNC,RNF146" Drug 2818_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ASIC1,NDRG2,ALCAM,MRTFA,CA4,CDH8,CACNA2D2,RCBTB2,FOXN3,AKAP7,ARHGEF10,ARHGEF4,PARD6A,DTNB,SGK2,EFNA3,SORBS3,PLEKHA1,HSD17B14,ERCC2,C1orf61,GAB1,DISC1,GPD2,LILRA2,GPER1,ADAMTS13,MAOB,MAP4,NEFM,CLDN11,PLCD1,PLTP,LRP12,ZSCAN2,RPS6KA2,SBF1,STUM,EPN2,SMTN,LHPP,PHLDB1,ARC,POPDC3,TBCEL,WSCD1,SZT2,PSD3,DICER1,ZNF34,TK2,AMOT,PLPPR2,KLC2,MPPE1" Drug 5405_UP Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ARID1A,AK2,CDC14B,SEMA4G,ASPH,BTRC,CAMK2G,QKI,CNTN1,SLC4A7,MYEF2,RUSC2,DTNA,EGR3,PCOLCE2,FECH,PDLIM5,USP19,PCDH17,RAB30,GNAL,GRIK2,NR3C1,GRM1,GSTM5,GUCY1A2,RASSF8,ICA1,JAK2,ADAM11,AFF1,MYO7A,NNAT,NUMA1,PDE3B,PLCD1,SMOX,PPARA,RET,RFX2,SALL1,SYBU,SLC2A5,SMARCD3,SNCA,DOK5,ARC,ANKRD12,PDLIM2,TBCEL,TIAM1,BCL2L13,GDPD5,SEMA3B,NAV2" Drug 2528_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "RALGAPA1,TKTL1,ARID1A,NDRG2,AGT,BCAR3,MRTFA,APP,PLA2G4C,PDE8B,CCDC181,CADM3,AZGP1,PROM1,LDLRAD4,B4GALT6,SLC4A8,CTNND1,DGKG,DAPK3,HEPH,MFAP3L,DLG3,DLG4,CNNM1,SIDT2,TNK2,EIF1,DMTN,APC2,INPP5K,PCDH17,RUNDC3A,GNAO1,GNG4,NCKAP1L,KLF12,MDM4,NPTX1,CCSER2,PPP5C,PTAFR,ZSCAN2,RAB3IL1,RGS12,RNASE1,SCG5,EPN2,LIMS2,SPTB,CLSTN2,INKA2,TCF7L2,CRTC1,TIAM1" Drug 3302_DN Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AP2A2,AK2,ALCAM,APBA2,KCNAB2,EPB41L5,GAS7,APOC1,ALDH4A1,STX16,CFLAR,SYNJ2,ARHGEF1,FADS2,QKI,ENTPD4,FAM169A,GREB1,DAPK3,ARMCX2,RABGAP1L,MBNL2,SORBS3,DMTN,INPP5K,PRRC2B,HNMT,HSD17B1,TJAP1,ITPKB,IPO5,MAP4,MPP2,MSI1,NEK1,NUMA1,GON4L,GTDC1,SLC25A36,NEK11,RPS6KA2,FAM214B,LIMCH1,RBM34,ATP11A,EXOC7,TBL1X,TCF7L2,PCDHA6,ZMYND8,PLPPR2,ZFP37,ZIC3,PRDM2,ST7" Drug 4125_DN "Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ADORA2A,AK2,LTBP4,MRTFA,APBA2,FAM131A,BRINP2,CFLAR,GYG2,BTRC,CFAP410,CAMK2B,PLEKHB1,PLAA,QKI,ARHGEF4,RUSC2,KBTBD11,DNM2,SGK2,MBNL2,ING4,TNK2,DLC1,TRAF3IP2,GLYR1,GLS,FERMT2,NR3C1,GRM8,IL6ST,KCND3,MPP2,NTRK2,STRN3,LRP12,MAPK8,PTHLH,RGS12,TCP11L1,SEMA6D,FAM214B,TSNAXIP1,ZHX3,STX1A,PLCB1,ATP11A,ROBO3,KIAA0930,PSD3,TNS2,AP4E1,PARD3,CABIN1,LMF1" Drug 4767_UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "SYN3,ASIC1,AMPD3,GAS7,SEPT7,CDO1,ZFYVE9,QKI,SULT4A1,FAM149A,AKAP6,TCEAL2,HAPLN1,AATK,DCT,RUSC2,C2CD2L,PRELID3A,CHL1,GAD1,ERAP1,GNG3,PRUNE2,GRM7,KLF12,ICA1,KCNH2,KCNMA1,SMAD1,AFDN,ADAM22,NTRK2,OPCML,CDK18,PFKFB2,PLCD1,PPP2R2B,PRKCB,PTAFR,TCP11L1,SH3GL3,CNKSR2,PKNOX2,TNIK,KIF21B,EMC1,CDK19,ATP10B,MAPK8IP3,TCF7,ZEB1,TNS1,SLC13A3,AP3B2,SENP7" Drug 4825_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "APC,APOC1,RGS20,PDE8B,ALDH7A1,CADM3,BAIAP3,CAMK2B,P2RX6,ARHGEF2,CDH8,CRLF1,ASIC3,TAOK2,CLTB,IFFO1,MYRIP,CHD5,CNTNAP2,FAM131B,RUSC2,EFNB3,EGFR,C3orf18,EN2,RASGRP2,EPHB1,CAMSAP1,FOXG1,CAMKK2,ERAP1,SIGLEC8,ALDH1L1,PCLO,ICA1,ITIH2,KCNH2,MID1,GPR173,CDK14,PPP5C,PTPRD,NUDT11,CARF,ZFP30,LIMCH1,VAMP1,POPDC3,CRTC1,AP4E1,TMPO,UGT8,SLC26A10,PRDM2,NT5M" Drug 2790_UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NDRG2,NLGN4X,OSBPL1A,KCNAB2,APP,SCAPER,CACNA1I,CBLN1,CBFA2T2,RCBTB2,AKAP7,VCAN,DCT,HEPH,SRGAP3,SGK2,MBNL2,HSD17B14,F3,ZNF589,FGFR1,CAMSAP1,GCNT2,GNAL,GPR22,GPER1,HLF,ICA1,MATN3,BCO1,PIK3CD,SLC25A23,PRKCB,MAPK8,GRAMD1C,PTHLH,C1orf54,CLIP1,ASAP3,DOCK10,RAB3GAP1,SHANK2,LIMCH1,KIF13A,ARC,POPDC3,DICER1,TK2,FAM155A,UBE3A,FLRT2,VAV2,WIPF1,ADAMTS9,KAT6A" Drug 7225_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NDRG2,AK2,APBB2,APOC1,PPP4R4,ARRB1,CAPRIN2,ST3GAL5,CHGA,CNTN1,ARMC8,FAM149A,NRG2,AKAP12,CSF1,ARHGEF10,SDC3,SRGAP3,HIPK3,EFNB3,HSD17B14,VPS13B,RASL12,REEP2,BAIAP2,ERAP1,SIGLEC8,GPD2,GRK4,GSN,HTR2A,TAGLN3,ZNF862,NEK1,RETREG1,LRP12,MINDY2,PEX5,KHDRBS2,RGS10,EMID1,ASAP3,PKNOX2,SPTAN1,ATP10B,MAPK8IP3,PLCB1,WSCD1,PSD3,FAM155A,VAV2,ZNF74,GDPD5,UBE3B,PHTF2" Drug 3359_DN Nadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ASIC1,ALCAM,LTBP4,APOC1,CFLAR,SEPT7,CDH10,ZFYVE9,FADS2,CNTFR,CNTN1,CSF1,ARHGEF10,RIMS3,SPOCK2,KBTBD11,HIPK3,SORBS3,DLC1,SCARA3,GPR153,INPP5K,SRCAP,RASSF8,INPP5B,KCNJ5,VWA5A,MYO7A,OPCML,PDE3B,PDPK1,PENK,PRKAR1B,MAPK8,PRODH,FAM120C,RAB3A,RAD52,RGS12,FAM192A,SH3BP2,PPP4R3A,SNCA,THSD1,INKA2,VAMP1,POPDC3,SYNE1,PSD3,DICER1,TGFBR3,TRPC1,KCNK12,ST7,ADAMTSL3" Drug 3802_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "BEGAIN,APBB1,BCHE,NRP2,BMP7,BTRC,TCEAL2,CRMP1,TENM4,PHF14,PPP6R2,C2CD2L,PARD6A,STX2,KCNMB4,GPM6A,GPR17,INPP5B,ITGA7,KCNB1,KCNMA1,LMO2,MAP2,MAPT,NEUROD1,SLC11A2,PDE4A,PDE4B,EPN1,PLXNB1,PTN,RAB3IL1,RGS4,ZNF821,RASA3,RPH3A,PREX2,ZNF334,CDK5RAP2,SNCA,KDM4B,ZHX3,DDN,COBL,KAZN,TCF7L2,CHST8,TNS1,AMACR,FLRT2,MICAL1,XRCC4,EMSY,NT5M,EVI5" Drug 4250_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "DPF1,ASPHD1,ADORA1,NME5,PKP4,CCDC181,ATP2B3,BACH1,NRP2,SYNJ2,CALB2,HAP1,CNTN1,CNTNAP2,RIMS2,DCC,HS3ST2,DTNA,PTK2B,SYT17,ATP8A2,SRCAP,GNAO1,GRIA4,ICA1,KCNB1,KIT,VWA5A,MAP2,NF1,NOS1,PTPRN2,ACSS3,RGS10,KLHL11,PBRM1,MYH14,CARF,PNMA8A,GSTCD,RPS20,SPTB,CDK19,ACSBG1,ARHGEF9,ASTN2,MCF2L,TBCEL,GPR161,ZNF34,CADM1,FLRT2,ZNF24,ZNF225,STMN4" Drug 7333_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AP2A2,CDC42BPA,APBB2,APOC1,PPFIA3,EIF4G3,MTMR2,ARHGEF1,UBE2L6,PLEKHB1,STOML1,EDRF1,DBN1,TSPAN5,SORBS3,GALC,SEPT9,AHDC1,GPR19,GRB10,KCNF1,MAN2A2,MAP4,MATK,GIT1,ZNF862,NAP1L1,PDE4A,PLEC,LRP12,PRKAR1B,MAPK8,CEP97,RAD51D,DPF2,RNASEL,GSTCD,TRAPPC13,SH3BGR,AMBRA1,ANKRD6,ZHX3,TSPYL2,STX1A,ATP11A,TIAM1,ZNF24,ZBTB38,MAP3K12,EMSY,DNALI1,MARCH8,UBE3B,SMIM8,PHTF2" Drug 2207_UP Betonicine [515-25-3]; Up 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ACTN2,MTUS1,BIN1,CDC42BPA,ANK3,BMP7,HIP1R,CDC42,CACNA2D2,CHM,ZFYVE9,STOML1,CNTN1,AKAP6,SIPA1L1,RIMS2,SV2B,RABGAP1L,DSCAM,FAM13A,MTSS1L,ERBB2,ZNF44,INPP5K,GRM3,KIF3A,MPP2,NTRK2,PGAM2,PIK3R1,PLEC,POU6F1,MAPK10,RELN,PTN,MYH14,PLPPR3,ASAP3,SLC1A7,SHANK2,SNCA,WDTC1,ZHX3,HECW1,ZBTB43,SPART,ATP10B,SYN2,EXOC7,TCF4,SLC35G2,ATP13A2,VAV2,KLC2,SLC17A7" Drug 2764_DN Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AK2,ATM,CFLAR,GYG2,CA4,RAB28,DZIP3,PPP6R2,TM9SF4,TBC1D5,DBT,HP1BP3,RABGAP1L,DTNA,EFNA3,ABI2,SORBS3,ZNF589,ANKFY1,GPR153,ERAP1,DISC1,MSL3,GNG4,ARHGAP19,KPNA5,NF1,NRGN,NUCB1,PDE3B,SLC25A23,PEX5,NKAIN1,RGS10,TCP11L1,PAQR6,WLS,SLC6A8,LIMCH1,TSPYL2,SS18,INKA2,STX1A,SUPT5H,TRIM2,AHCYL2,TMOD1,RBFOX2,TRIO,ZMYND8,VGF,DNALI1,HPS4,RNF170,SENP7" Drug 2424_DN Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ADORA2A,KIDINS220,MRTFA,PPFIA4,APBB2,APP,FOXN3,CLCN4,STOML1,BAG4,CREM,CRY2,DGKG,C2CD2L,EFNA3,LPAR6,ING4,SRCAP,COPS8,LILRA2,PADI2,AGFG1,JAK2,LSS,SMAD1,MAP4,NF1,NINJ2,NPR2,SLC11A2,PDE4D,GPR85,PPP3CC,CNNM2,PTAFR,RAB3A,ZNF493,RGS10,SH3BP2,PEX26,SLC20A2,SPTAN1,CDK19,ZBTB43,MAPK8IP3,CEP68,ARHGEF9,CAMSAP2,ADGRL3,FBXW11,TBL1X,TCF7L2,KAT6B,ZKSCAN5,GDPD5" Drug 6678_DN Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ARID1A,ADD2,ADRA1D,NME5,APAF1,APC,DNAH17,ASPH,ADAM23,CHN2,TAOK2,PICK1,SH2B1,AATK,VCAN,ARHGEF4,SPOCK3,RABGAP1L,PLXNC1,TENM1,MTSS1L,FYB1,ZNF44,GNAL,GPR19,GPR37,GRM8,HLF,LSS,MAPT,TM6SF1,MMP16,NDUFA5,NF1,NOVA2,SLC11A2,ODF2,PROX1,SAMD9,KCTD17,ZNF821,MRAS,CNKSR2,NLGN1,RPH3A,SPTAN1,DDN,ATP11A,SLC44A1,THRA,TK2,VIPR2,WIPF1,XRCC4,NAV3" Drug 4105_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ALCAM,PPFIA4,CACNA1I,CACNA2D1,CACNB2,SLC16A4,CHRNB2,CRY2,NCOR2,PDE4DIP,CNTNAP2,ST18,DAPK1,SPOCK2,ATN1,EDNRB,EFNB3,ELAVL3,MTSS1L,FABP7,DCTN2,GAB1,GABRA5,SRCAP,GLRB,ICA1,KCNC1,KCNH2,KCNN1,LMO1,MOBP,ADAM22,MX1,NTRK2,ENPP2,EPN1,PACSIN1,POU3F4,PID1,ZNF493,RGS3,RGS10,GSTCD,TMEM206,WLS,DOCK10,SLC2A5,SHANK2,LIMCH1,ATP10B,PHLDB1,WSCD1,TMOD1,SLC17A7,SSPN" Drug 6015_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AP2A2,PLA2G6,ALCAM,AMH,AMT,APBA2,APLP1,NCOA1,SLC2A11,ADAM23,BCL7A,MTMR3,CBFA2T2,ARHGEF2,ARHGAP33,ADGRG1,VAX2,AKAP7,CREM,LRIG1,FEZ1,PDE4DIP,CNTNAP2,SDC3,CDON,FCF1,MRNIP,EPB41L1,LRRC23,F3,GABRA2,GLYR1,RAB30,GRM1,MAP4,MBD1,LYRM9,NDUFA5,NF1,SAMD9,NKAIN1,ROBO1,ANKRD6,EPN2,FAM214B,CXXC4,SNCA,CEP68,IQCE,TCF7,CABIN1,RBFOX2,VAV2,LMF1,ZFP37" Drug 2796_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "MRTFA,BIN1,APC,AQP6,SLC4A4,CFLAR,SLC16A4,CDC42,RCBTB2,ASIC3,TAOK2,ARHGAP22,FADS2,WHRN,NRG2,NECTIN3,DGKG,DBT,DNM1,DTNB,EFNB3,TNK2,DMTN,AFF2,DPYSL4,ADAM28,TDRKH,GRB10,GRIK5,NR3C1,RASSF8,HNMT,TJAP1,KCNN1,P2RY1,PLCD1,SLC25A23,PKN2,CNTLN,PTCH1,RAB3IL1,ROM1,RYR1,SH3BP2,ST6GAL1,NLGN1,PREX2,ZC3H13,ST5,ARC,HIF3A,ZNF34,TK2,CABIN1,PRDM2" Drug 2724_UP Amrinone [60719-84-8]; Up 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "NDRG2,APC,EPB41L5,PRX,ALDH4A1,CACNA1G,CACNA2D1,CDH8,LARGE1,CHN1,FAM149A,SIPA1L1,CNTNAP2,INTS1,EDNRA,EFNB3,EGFR,ELN,C3orf18,TBC1D16,ATP8A1,FHL1,PRELID3A,GPR153,PCDH17,HTR2A,TJAP1,SCIN,KCND3,FXYD7,NCAM1,NEFM,NOS1,OMG,OXTR,PLCD1,PURG,POU3F2,PKIA,SYTL2,WDR25,PTPN13,RGS3,RPS20,ASAP3,BCAN,PKNOX2,SNCA,ZSWIM8,ROBO3,TEX15,ZFPM2,CHST8,RUNDC3B,BEST1" Drug 6646_UP Progesterone [57-83-0]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "ADRA1D,AGT,APBB1,PRX,PDE8B,ATP2B3,ADGRB3,CFLAR,BTRC,KALRN,SCARB1,CDH10,CNTN1,TCEAL2,NCOR2,CSF1,PLCH2,CHD5,CNTNAP2,INTS1,BRINP1,SRGAP3,DSCAM,DTNA,EBI3,TNK2,ETV1,FGF12,AFF2,GRM1,SHISAL1,ITGA7,KCND3,KCNJ5,AFDN,ADAM22,NTRK2,OGG1,PTPRB,RGS12,SLA,SLC1A7,ATP10B,PLCB1,MCF2L,PCDHGB6,AP4E1,DAAM2,TRO,CADM1,FLRT2,KCNK12,PRDM2,KCNAB1,FAM13C" Drug 262_DN "indomethacin, USP; Down 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Down 7.64E-06 3.74E-01 1.33E-04 1.52E-03 55 196 "AP1B1,KIAA1324,ANK1,ASCL1,RASL11B,SLC4A4,CBLN1,ARHGAP33,CACNA2D2,CP,SIPA1L1,ECE2,KLHL3,EDNRA,SIDT2,LRRC23,CACNG2,ATP8A1,FGR,NSG1,LUZP2,GNAO1,LILRA2,GRIN1,BTN2A1,AP4S1,SYNPO,HNMT,IGF1,KCNA1,KIT,LAMA2,STMN1,MATK,NCAM1,SLC11A2,SETD4,GDAP1L1,PPP2R5C,PTK2,ZCWPW1,KLHDC8A,SH3BP2,FERMT1,SLC6A11,SLC8A1,KBTBD4,ZCCHC24,ZC3H13,TACC1,FAM208A,DOCK9,CDH22,RIMBP2,TFIP11" Drug 7503_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.65E-06 3.75E-01 1.33E-04 1.52E-03 52 182 "ADRB2,ALAD,MRTFA,MARK4,ADGRB2,ST3GAL5,BAIAP3,CDK5R2,HIP1R,USP2,STOML1,ABCG1,PDE4DIP,CNTNAP2,NOS1AP,SRGAP3,EFNA3,TUBB4A,TESK2,BAIAP2,DPYSL4,PDLIM5,CYP46A1,SLC2A6,ITGA7,KIF5C,LSS,MAPT,TAGLN3,ODF2,PCDH9,SERPINI1,PIK3CD,PRPH,RAB3A,KCTD17,RPS6KA2,FAM102A,ASAP3,ARFGAP1,KDM4B,ARHGAP26,SPTAN1,THSD1,ELOVL4,CEP68,RGL1,SYT11,ARC,SYT1,SMG6,R3HDM1" Drug CID000004197 milrinone Stitch 7.75E-06 3.80E-01 1.35E-04 1.54E-03 45 150 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRB2,PDE8B,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA2D1,CALM1,LRBA,PLCXD3,ENPP6,ATP2C1,GPT2,PLCD4,CIT,GUCY1A2,GUCY1B1,NOS1,NPPA,NPR2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PLCB2,PLCD1,PRKACB,GDPD2,SMPD3,FNDC3A,PLCB1,SYNE1" Drug 7105_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.00E-06 3.92E-01 1.40E-04 1.59E-03 50 173 "ABAT,ADRB2,APBB2,ARNTL,MARK4,ST3GAL5,SYNGR3,REPS2,CSNK1E,PDE4DIP,CTH,RIMS3,C2CD2L,PLPPR4,EFNA3,TAOK3,DLC1,ATP8A1,TESK2,BAIAP2,SORBS1,PDLIM5,FYN,KIF5C,MEF2C,NRGN,PCDH9,SERPINI1,PIK3CD,RETREG1,PRPH,PTCH1,ENOX1,RBBP6,RGS4,FBXW7,SH3GL2,SH3GL3,ASAP3,FAM214B,DOP1A,THSD1,RGL1,SYT11,VAMP1,SYT1,COBL,ARHGEF12,SSBP2,DNAJC12" Drug ctd:D001104 Arbutin CTD 8.02E-06 3.93E-01 1.40E-04 1.59E-03 73 283 "KLRC4,KLHL13,PARG,CPNE5,NRP2,BMPR1B,FMNL3,INA,ARHGEF2,KCNAB3,TMEM59L,IGDCC3,FRMPD4,DDX46,DLX1,DPYSL2,CACNG7,EFNA3,EMX2,VPS13B,EPS8,NCALD,EFS,FGFR3,C1orf61,FAM49B,BRSK1,GALC,C15orf41,HTATSF1,GPD2,B4GALNT4,GPR26,BTN2A1,GUCY1A2,MAP4K5,PACSIN2,HLF,NEGR1,NKD1,IL6ST,GPR155,MDFI,PRRX1,RASGEF1B,MAPK8,APTX,PSMD13,KCTD17,PCMTD2,LRRTM4,SH3GL2,ARX,ASAP3,FBXO11,CNKSR2,RAB3GAP1,ERC1,LRRC4,APOM,TAL1,VWA3A,SIN3B,NEU4,TCF12,DNAH7,TSC1,PRR18,PITPNB,OSBP2,ADAMTS9,SOCS4,SPATA13" Drug CID000003758 IBMX Stitch 8.02E-06 3.93E-01 1.40E-04 1.59E-03 90 368 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,APOC2,MIER1,ARSE,PDE8B,ALDH7A1,RIPK1,HCN2,CACNA1D,CACNA2D1,CACNB2,CALM1,CCK,KRIT1,LRBA,CHRM1,PCYT1B,AKAP6,HAPLN1,VCAN,DBI,DCT,EDN1,ENO2,TUBB3,FGF1,FOXM1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GFAP,BRD8,CRCP,GNAS,GPD1,GPD2,RAPGEF4,NR3C1,GUCY1A2,GUCY1B1,TNFAIP8L3,IGF1,MITF,NOS1,NPPA,NPR2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PLIN1,TRHDE,PPARA,PRKACB,PRKCB,PRKCG,MAPK3,PTHLH,PTH1R,PYGM,RIT2,SST,SSTR2,AZIN2,CDK20,TRH,VIPR2" Drug CID000030956 AC1L1KMJ Stitch 8.03E-06 3.94E-01 1.40E-04 1.59E-03 111 476 "ACTN1,ADD1,ANK1,ANK2,ANK3,MYH7B,GAS7,SPTBN4,DST,CALM1,CAST,LRBA,CDC42,CDH2,CHRM1,EPS15L1,MYL6B,CLTC,TJP2,CNTN1,CABP1,COL4A5,COL9A1,COL9A2,COL9A3,COL11A2,MYRIP,AKAP12,CALY,DBN1,DCTN1,SACS,DLG4,DNM1,DNM2,DNM1L,EDN1,ABI2,TNK2,TUBD1,VPS13B,APC2,PTK2B,TUBB3,TUBB4A,ACTL6B,BAIAP2,DCTN2,NRG3,FYN,TUBA8,TUBA1C,RAPGEF1,GSN,PSIP1,ATCAY,MYLK2,IGF1,TUBB2B,ITGAM,LAMA2,MAP2,MATK,TAGLN3,MYL3,MYO6,MYO7A,OLR1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLEC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,PSMA6,LAMA1,PTK2,PTPRB,RDX,FBXW7,RPS6KA2,CLIP1,MAPK12,FNDC3A,SLA,SLC9A5,SLC12A2,SPTAN1,SPTB,JMJD6,TF,TIAM1,TJP1,ACTR6,TMOD1,TPD52,TPM1,TPM2,TPM3,TPM4,TRPC1,TUBB2A,TUBB1,VAV1,TUBA1A" Drug CID006450319 polysialoganglioside Stitch 8.09E-06 3.96E-01 1.41E-04 1.60E-03 21 50 "SYN3,ADD2,CA12,CANX,SIGLEC8,NEU3,GRIK1,KCNA1,MAG,NTRK3,CLDN11,PKM,PRODH,FNDC3A,SNAP25,SYN1,SYN2,SYT1,NEU4,TNFRSF1B,SIGLEC10" Drug 3893_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.11E-06 3.97E-01 1.41E-04 1.61E-03 53 187 "ADRA1D,BIN1,ANK2,KCNAB2,PLA2G4C,ATP1A3,ATP2B2,CACNA1I,CFAP410,CBARP,CNTN1,MYRIP,PDE4DIP,CDON,RCAN1,EDNRA,ELAVL3,DLC1,FGF1,FGFR1,FOXG1,FYN,GFER,RND1,PTGDR2,KCNH2,KCNJ5,MEF2C,MIA2,ADAM22,NKX2-2,OMG,SERPINI1,PLCB2,GRAMD1C,RELN,ZDHHC14,CRTAC1,MYH14,CARF,KCNIP1,CLIP1,SATB1,STUM,CPEB3,ARHGEF40,IZUMO4,ZC3H13,ABCC8,ARC,TNS1,LAT2,SLC13A3" Drug 5678_UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.11E-06 3.97E-01 1.41E-04 1.61E-03 53 187 "ADORA1,PLA2G6,MRTFA,BEGAIN,SLC4A4,MTMR7,CHM,LHX2,HAPLN1,NCOR2,CSF1,CNTNAP2,ARHGEF4,EDRF1,ARHGAP24,DGKB,DSCAM,EGFR,EGR3,EIF4G2,COQ7,FYB1,SIGLEC8,SRCAP,LYVE1,GLS,GNAO1,TDRKH,GRIK5,SLC2A6,GPR45,LSS,MEF2C,PAH,PCSK2,PPP1R1A,MAPK8,PTCH1,SH3BP2,PPP1R9A,SHANK2,KDM4B,TRIM2,DICER1,ZNF34,PARD3,TPM2,TRO,VLDLR,WIPF1,PRDM2,KCNAB1,EPM2A" Drug 5854_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.11E-06 3.97E-01 1.41E-04 1.61E-03 53 187 "ADCY6,ALAD,NRP2,CFAP410,CACNG1,MAP7,CBFA2T2,WHRN,AKAP12,CSF1R,VCAN,CTH,MFAP3L,ELAVL4,FABP7,ZNF589,FOXG1,PNMA2,TBR1,GNAO1,GPD2,LPAR4,RAPGEF1,GRIK5,KCNMA1,KIFC3,MAPT,MIA2,ADAM22,PDE2A,GPR85,SMOX,PPP5C,MAPK7,PTHLH,PTPRH,TMEM231,PID1,PNMA8A,TCP11L1,FAM214B,SLC6A9,SLN,KIF13A,KDM4B,ATP10B,COBL,KAZN,PCDHGA10,TRIO,TUB,VGF,SLC17A7" Drug CID003309928 1-norokadaone Stitch 8.12E-06 3.98E-01 1.41E-04 1.61E-03 9 12 "CAMK2B,CAMK2D,DNAH9,NR3C1,KCND2,PTPA,PPP3CA,PPP3CC,CABIN1" Drug CID004346372 AC1N8N2J Stitch 8.14E-06 3.99E-01 1.42E-04 1.61E-03 12 20 "DLG4,GAD1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRM3,SYNPO,MAP4,PTCH1" Drug 6149_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.28E-06 4.06E-01 1.44E-04 1.64E-03 48 164 "ABAT,TKTL1,ADD3,GRAMD1B,MTUS1,BIN1,DNAH17,C5,MAP7,CD86,REPS2,CHN2,CREM,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,DOCK4,SGK2,FAM13A,ING4,DMTN,ERBB2,BAIAP2,C1orf61,TRAF3IP2,MYT1,OLR1,TREM2,PCSK5,PDE4B,PDE4D,SERPINI1,SSH1,PLCL1,PILRA,CARF,SATB1,SGK1,TMCC1,SPTAN1,CDK19,PLCB1,SLC35G2,TK2,FLRT2,LMF1,MAP3K12" Drug ctd:D012643 Selenium CTD 8.36E-06 4.10E-01 1.45E-04 1.65E-03 315 1605 "SERPINA3,DGCR6,ABR,ACHE,RBM10,AS3MT,ACTN1,ADCY2,ADCY6,ADD1,ADD3,ADORA2A,AP2A2,AP1B1,OSBPL1A,AK2,ALAD,ALCAM,LTBP4,AMPD3,BIN1,CDC42BPA,ANK3,APC,APP,CDC14B,CDK10,PRX,ARHGDIA,DDX3Y,ALDH4A1,SLC4A4,MTMR9,ADGRB1,BARD1,BID,CFLAR,SYNJ2,SCAPER,LDLRAD4,THSD7A,CAMK2B,HIP1R,RUNX1T1,NFS1,ZMYM4,LRRFIP1,SRSF11,CHN2,CHRNA4,CNOT8,SLIT2,CLCN3,CLU,TPP1,CLTB,NIPBL,CNN3,IQCK,FAM149A,SLC4A7,RCHY1,CSF1,CSNK1E,CST3,SDC3,KIAA0040,PPP6R2,TCAF1,ZNF337,TM9SF4,INTS1,DAPK3,SIRPA,DCTN1,HEPH,B3GAT3,FBXL5,RUSC2,COPS7A,CEP170,MED24,MAGI2,GSDME,RHOBTB1,SMG7,SACS,SEC16A,USP3,DMTF1,ECM2,FIS1,E2F6,EDNRA,EEF1A2,EEF1D,OPTN,EGFR,AASS,EIF4G1,SORBS3,BSCL2,USPL1,PLEKHO1,ENO2,MFSD10,ERBB2,GMPR2,ECSIT,TUBA1B,TUBB3,SCML2,FCGRT,FDFT1,PRMT5,FECH,SEC24B,ATP5PD,SEC23B,CAP2,FOXF2,SYNCRIP,FOXO3,FLT1,NOP56,FOLH1,ARFGAP2,ATP2C1,ERGIC3,STAG2,RAPGEF6,ZNF274,INPP5K,ALDH1L1,MALT1,GJB1,DHRS4,RND1,TCERG1,RNPS1,HPGDS,GLI2,OS9,POLL,GNAS,ADAP1,GRIA2,NR3C1,GSN,GSTT2,PSIP1,FAM107A,MAP4K5,MAN1B1,KLF12,HLF,HMGB1,SCRG1,SYNPO,HMGCR,HMX1,HNMT,HSP90AA1,ICA1,IDH3B,IL6ST,KIF5C,KTN1,PAXBP1,MAP4,MBD1,MBNL1,MBP,CHST6,MMP16,PTOV1,MT3,THYN1,MX1,MYO6,NACA,HNRNPM,NASP,NEK1,NFE2L2,SLC11A2,NUCB1,OGG1,OPA1,PC,PCDHGC3,PCSK5,PDPK1,OLA1,PIK3CD,CCSER2,PKD1,PKM,PLEC,SMOX,RETREG2,EPB41L4B,TNPO2,PTPA,PPP2R5E,PRKCB,PKN2,MAPK3,MAPK8,MAPK9,PIGG,PTAFR,PTPRO,PTX3,TUG1,USP47,C1orf54,FAT4,ZCWPW1,RBBP6,KCTD17,RNF220,SLC25A36,RNH1,ALG9,RPL38,RPS6KA2,RPS20,RXRA,SAFB,SATB1,ATXN1,ATXN7,PPP1R9A,FERMT1,ASAP3,CHD9,FBXO11,FHOD3,SEC31A,EPN2,DHX30,SMTN,SLC6A8,SHANK2,SLC12A2,SMARCA4,SMARCD3,RCOR3,TTC17,LIMCH1,SNAP25,PALLD,USP33,SON,ZCCHC24,UHRF1BP1L,SPP1,UNC5B,SPTAN1,TROVE2,ST5,NCDN,GANAB,SUPT5H,PRRC2C,DNAJC9,MMS19,PJA1,MLST8,MCF2L,FAM208A,TBL1X,ATMIN,EHBP1,SIN3B,DMXL2,TCF7L2,ZEB1,TCF12,OBSL1,TNS2,CRTC1,DICER1,SIRT1,TGFBR3,HHIP,THRA,TIMP4,TJP1,CBX5,R3HDM1,CABIN1,TPM2,WBP2,TRO,TSC2,TTC3,GORASP1,OSBP2,VGF,SF1,ZNF195,UPF3A,INTS3,EMSY,PRDM2,LRP8,EVI5,SEMA3B,NAV2,ITM2C,PDSS2,NLRP3,FXR1" Drug 3998_DN Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.54E-06 4.18E-01 1.48E-04 1.69E-03 51 178 "ADD3,CDC42BPA,PKP4,CDC14B,ASPH,SPAG9,CDC27,SLIT2,TBC1D5,NR1D2,EGFR,EIF4G1,WAC,POLR1B,GART,SPIN1,FERMT2,PCLO,AGFG1,IL6ST,MAP4,MBP,MYO6,NEK1,SSH1,RC3H2,MED1,TMEM260,PLEKHB2,RBBP6,SLC25A36,KIRREL1,SEC14L1,CCDC88A,SMARCC2,SON,MYCBP2,SRPK2,TROVE2,PRRC2C,TBL1X,EHBP1,TCF4,WASHC4,DICER1,KAT6B,USP1,ZBTB38,WNK1,SNX27,FXR1" Drug 5434_DN Piribedil hydrochloride [78213-63-5]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "ASIC1,PLA2G6,C1QTNF3,APC,CDC14B,KIF1A,MTMR2,BAIAP3,SOCS6,PLEKHB1,ARHGEF6,CNTNAP2,PPP6R2,DBN1,MFAP3L,DTNA,FCF1,CNNM1,EIF4G2,VPS13B,LRRC23,FGF12,GART,GCNT2,GLYR1,RAB30,GNAS,GPER1,CACFD1,ELOVL5,HSF2,MDM4,KITLG,ADAM22,NFYA,PDE3B,ELOVL2,TMEM231,RAD52,TCP11L1,ASAP3,SLC1A7,TROVE2,NXT2,MAPK8IP3,ATP11A,EXOC7,FBXW11,TMOD1,VIPR2,KCNK12,ZBTB14,SPHK2,RNF170" Drug 3976_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "ASIC1,AMPD3,BRINP2,BACH1,CFLAR,SCAPER,SGCE,CAMK2B,CDC42,ZFYVE9,CNTN1,NECTIN3,SIPA1L1,CYBB,EFNA3,EFNB3,RASGRP2,ANKMY1,F5,KHDRBS3,FUT9,HBS1L,SYT17,PCDH17,RUNDC3A,ADAMTS13,KCNN2,SLCO1C1,NPY,PCDHGC3,CDK18,PRPH,PTHLH,PTPRD,RIPOR1,RGS12,FBXW7,TCP11L1,CPEB3,SLC9A5,ZHX3,THSD1,ARC,ROBO3,CRTC1,DICER1,TK2,VAV1,WIPF1,LAT2,SPHK2,SEMA3B,ITM2C,MPPE1" Drug 4340_UP Ethisterone [434-03-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "ASIC1,PKP4,CDC14B,PPP4R4,ATM,BAIAP3,CACNB2,DNAJB5,IFFO1,GIT2,ZBTB24,SMG7,SGSM2,RABGAP1L,EDN1,SEMA3D,OLFM1,FGFR1,ZNF44,RUNDC3A,GPR22,PADI2,IL6ST,KCNJ5,KIF5A,KIF5C,MAP4,ADAM22,NELL2,NPTX1,NUMA1,PAK3,PBX1,STRN3,POU3F4,MAPK8,RGS4,KIRREL1,FOXRED2,SCNN1D,CPEB3,FBXO11,CNKSR2,ANKRD6,SNCA,IQSEC2,COLGALT2,TBL1X,DMXL2,HIRA,SF1,WNK1,KCNAB1,KAT6A" Drug 3318_DN Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "RALGAPA1,AP2A2,MARK4,ATM,CFLAR,SYNJ1,CACNB2,ARHGEF2,MAGI1,SOCS6,SLC4A8,SDC3,GREB1,DCAF8,TBC1D5,MFAP3L,RUSC2,KBTBD11,SORBS3,DMTN,DPYSL4,FAM49B,DISC1,RUNDC3A,TDRKH,EML4,SPACA9,CACFD1,TJAP1,KCNH2,KCNN2,MAN2A2,NF1,LRP12,PTHLH,PEX5,RAB3A,FBXW7,PREX2,SLC15A2,SLN,UNC5B,SPART,TCF7L2,PSD3,PCDHA6,ZMYND8,PLPPR2,VGF,XRCC4,ZFP37,WNK1,VPS35L,SSPN" Drug 7542_UP Ald1.1-H_000455; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "C1QTNF3,SEMA6A,AMH,AMPH,BIN1,AMT,APBB2,DDX3Y,SLC4A4,BMP7,SYNJ2,CAMK2B,CBFA2T2,CDH18,RAB28,IQCK,NECTIN3,DMPK,DTNA,ELAVL2,ZNF589,GPR153,DISC1,ADAM28,MSL3,ATXN2L,MMP16,ZNF862,NF1,SLC11A2,PLXNB1,PEX5,ZFHX4,ASAP3,COA1,TSNAXIP1,DOK5,TROVE2,NXT2,MAPK8IP3,EXOC7,HEY1,HEY2,DAAM2,CDK20,METTL3,TRPC1,PDIA2,LMF1,REEP1,TFIP11,EMSY,ADAMTS9,SENP7" Drug 3469_DN Butacaine [149-16-6]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "ABHD6,EPB41L5,FAM131A,PPFIA3,APP,ATM,CFLAR,CFAP410,CAMK2G,ZFYVE9,TPP1,VAX2,CHD1L,CREM,EDRF1,GIT2,FBXL5,DSCAM,HIPK3,FEM1B,SIDT2,LRRC23,CDKL3,ZNF589,FHL1,ANKFY1,FAM49B,TRAF3IP2,GCNT2,CRCP,GLYR1,LPAR4,SLC2A6,HSD17B1,IL6ST,ADAM22,PDPK1,RETREG1,NLE1,SMIM7,MAPK8,SNRK,SLC25A36,CCDC25,EPN2,ZSWIM8,ARHGEF9,TCF7L2,AHCYL2,PARD3,CABIN1,LMF1,PHTF2,RNF170" Drug 4613_UP Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.56E-06 4.19E-01 1.48E-04 1.69E-03 54 192 "CDK10,ASCL1,ASPH,FGF17,BTRC,CACNB2,CACNG1,ARHGEF2,CBARP,FAM149A,AKAP6,CRY2,RGS6,TOX,MFAP3L,ARNT2,DRP2,DTNA,PLXNC1,EPB41,DCTN2,SIGLEC8,ADAM28,CSDC2,GNG4,GPD1,STMN2,SPACA9,KCNC1,MAN2A2,MAOB,MMP16,MT1M,NF1,CNOT4,PDE4D,FA2H,PRKAR1B,FAM120C,GSTCD,NEK11,RTN1,RASA3,SLC6A9,OGDHL,SORCS3,ARHGAP26,ARC,SYP,OBSL1,DNAH7,ZFPM2,TLR4,NLRP3" Drug CID000073960 glutamic acid diethyl ester Stitch 8.86E-06 4.34E-01 1.52E-04 1.73E-03 17 36 "ABAT,APP,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,PORCN" Drug 1793_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.91E-06 4.37E-01 1.52E-04 1.73E-03 49 169 "ABHD6,ADRB2,ARNTL,ST3GAL5,HIP1R,SPAG9,ABCG1,CTH,DNAJC6,EFNA3,FAM13A,EPS8,TAOK3,ATP8A1,TESK2,BAIAP2,FYN,GLS,EML4,BACH2,DIPK1A,KIF5C,PCDH9,PDGFRA,SERPINE2,PMP22,SYTL2,PTX3,RGS4,TTLL7,RPS6KA2,SH3GL3,CCDC88A,PALLD,KDM4B,DOP1A,TNIK,ZCCHC24,ARHGAP26,SPTAN1,THSD1,ELOVL4,RGL1,SYT1,COBL,AGTPBP1,HEY1,DNAJC12,DPF3" Drug 4745_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADRA1D,AMT,APC,MARK4,SLC2A11,SYNJ2,CFAP410,CAMK2G,ARHGEF1,B4GALT6,TAOK2,EPS15L1,WHRN,NCOR1,SDC3,MFAP3L,EDNRA,EIF4G2,HSD17B14,DMTN,FGFR1,AFF2,TDRKH,STON1,NR3C1,GRM8,ELOVL5,HNMT,JAK2,MAP4,MID1,MSI1,ADAM22,NUMA1,SERPINI1,PRODH,RAB3IL1,GTDC1,RGS3,NEK11,SBF1,ASAP3,SHANK2,SPTAN1,CLASP2,TCF7L2,PSD3,CRTC1,PCDHA6,ZNF34,TRIO,MICAL1,LMF1,SCG2,ZNF248" Drug 5361_DN Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ASPHD1,PPFIA3,NCOA1,BTRC,LHX2,RAB26,AKAP7,IQCK,ENTPD4,LRIG1,ZNF337,GIT2,LYPD1,CNNM1,ANKMY1,FECH,ZNF274,SEPT9,AHDC1,MSL3,KCNMB4,GOLGB1,NR3C1,INPP5B,MBD1,NUMA1,SETD4,OGG1,OPA1,RETREG1,PPP2R5C,PRODH,PRPH,APTX,PTCH1,RAB3IL1,GSTCD,FBXW7,ATXN7,FBXO11,SPART,CEP68,ARHGEF9,PDLIM2,TNS2,TMOD1,PARD3,KAT6B,CDK20,METTL3,TRPC1,ZMYND8,CLDND1,SMIM8,ZNF248" Drug 5939_UP PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AP2A2,LTBP4,APOC1,APP,CDC14B,BACH1,SCAPER,BAIAP3,CAMK2B,MAP7,CLCN4,DNAJB5,COL9A3,DAPK3,ATN1,ING4,TUBD1,EZH1,REEP2,PTK2B,FYB1,GART,SESN1,TXNL4A,HRH3,KLF12,SCIN,ITPKA,KIF5C,MAPT,ZNF862,NUMA1,CDK18,CDK14,PIK3R1,CNNM2,CNTLN,ZCWPW1,KCTD17,ROM1,RPS6KA2,ATXN7,SH3BP2,FBXO11,BTBD7,IQSEC2,MAPK8IP3,CEP68,VAMP1,CHST8,TK2,TNS1,MKRN3,MAP3K12,FZD3" Drug 6471_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,APC,GAS7,PDE8B,SLC4A4,ALDH7A1,ATP6V0A1,SCAPER,SGCE,SOCS6,WHRN,PDE4DIP,DAPK1,DCC,HS3ST2,ST8SIA3,SGK2,TENM1,ENO2,FGFR1,SEMA6C,ANKFY1,SORBS1,FYN,HBS1L,ERAP1,GPM6B,NR3C1,GRM8,GUCY1A2,PTGDR2,HTR5A,KCNMA1,KIF5A,LIG4,MBD1,ADAM22,NDUFA5,NOVA2,SLC25A23,MAPK7,ZSCAN2,NUDT11,TCP11L1,ASAP3,ANKRD6,ATP10B,SYT11,TAL1,SLC35G2,CLIP2,NDRG4,SLC30A3,EPM2A,JPH3" Drug 3796_UP Methiazole; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "SYN3,ADD2,KIDINS220,ASTN1,CADM3,AZGP1,ADGRB3,RGS9,MTMR3,RUNX1T1,SULT4A1,IFFO1,MAGI2,ATN1,MBNL2,ABCA8,GATM,NEU3,GNAO1,GRK4,GRM1,GRM8,GUCY1B1,IGF1,VWA5A,MGAT3,MMP17,CD200,NOVA2,NPTX2,GPR88,KCNK10,PDE3B,GPR85,DUSP26,C19orf57,POU3F2,POU3F4,PRKAR1B,WDR25,CNTLN,MARCH1,ZMAT4,RGS12,PNMA8A,FOXRED2,CNKSR2,KANSL3,PKNOX2,SCN3B,DOP1A,KIF21B,TRPC1,PARP6,PRDM10" Drug 3687_UP Glycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADD2,ANK1,BRINP2,ALDH4A1,ATP6V0A1,CAMK2B,CDO1,CHN2,SULT4A1,GPRASP1,G3BP2,EXOG,ATN1,DTNA,EDN1,FGF1,FGR,CAMSAP1,SEMA4D,SIGLEC8,GNAL,GRK4,GRM1,NXPH3,HSF2,TJAP1,INPP5B,ITGA7,KCNF1,KCNJ5,LSS,ADAM22,NPY,PDE2A,PIK3CD,PNMA3,NECAB2,TNPO2,RAD51D,RNASE1,STK32B,SLC1A6,SLC15A2,DOP1A,MLC1,VAMP1,MCF2L,PCDHGA10,PCDHA5,TMPO,TNS1,FLRT2,ZNF225,EPM2A,NLRP3" Drug 7350_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "CFLAR,CACNA1I,BTRC,TPP1,FAM189A2,QKI,CSF1R,LRIG1,CNTNAP2,FAM169A,TBC1D5,GIT2,SPOCK3,ATN1,EFNA3,ING4,ERCC2,ANKMY1,ZNF589,FGF12,RUNDC3A,STON1,GRIK5,ELOVL5,HNMT,INPP5B,KCNMA1,KIF5A,LSS,MEIS2,MSI1,ADAM22,NF1,NOS1,SLC11A2,PROX1,PRPH,SNRK,FAM120C,FBXW7,SBF1,ZNF821,SNCA,TROVE2,TTBK2,PCDHGB6,CRTC1,FAM155A,MICAL1,LMF1,XRCC4,WNK1,SEMA3B,NUP214,SSPN" Drug 6703_UP Mimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADRA1B,MRTFA,DOC2A,APBB2,APC,PTCH2,SLC2A11,NOL4,FUBP1,BTRC,CAPN3,CAST,USP2,CHN2,TAOK2,CLCN4,MICAL2,PDE4DIP,PHF14,TOX,PHYHIP,ATN1,EDIL3,ST8SIA3,MBNL2,ETV1,ATP8A1,ST3GAL6,GNAO1,PRUNE2,GRM8,ITGA7,LAMA2,MDM4,KITLG,MSR1,NOVA2,NPTX1,MAPK8,PTPRG,TCP11L1,ZFP30,FNDC3A,DZIP1,ANKRD6,ZNF423,SYT5,RPGRIP1L,RALYL,PCDHA5,TEK,TIMP4,BEST1,LAT2,NSD2" Drug 1597_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; HL60; HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,ADD3,ALAD,CDC42BPA,APP,CDK10,ATM,EIF4G3,ATP2B1,BACH1,WASF1,CAST,KRIT1,CNOT8,CNTFR,PPP1R16B,CTH,DCAF8,ZNF337,MBNL2,DCTN4,DENND4A,SEC23B,SMC2,STAG2,ERAP1,IRAK3,KTN1,LAMP2,PDE3B,PIK3R1,RETREG1,PLCD1,LRP12,PPM1B,PPP2R5C,ATXN7,SCP2,SEC14L1,CCDC88A,FNBP1,UHRF1BP1L,EPB41L3,NEK4,KLHL7,ARHGEF12,TK2,TNS1,HIRA,UBE3A,WIPF1,TRIM9,ZNF142,EPM2A,RNF170" Drug 7447_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,SEMA7A,SLC4A4,BMP7,CFAP410,CACNA1D,CAMK2G,CBFA2T2,ARHGAP33,CHM,CNTNAP2,FAM169A,HS3ST2,DPP6,ING4,ACSL4,OLFM1,FGF12,BAIAP2,FOXG1,C1orf61,GAB1,B4GALNT1,TXNL4A,ADAMTS13,KCNJ5,LMO2,MAP4,MIA2,ZNF862,NOS1,ENPP2,RETREG1,PLCD1,PLXNB1,PPP2R2B,PRKAR1B,RIPOR1,GAL3ST4,KCTD17,RNASEL,GSTCD,RPS6KA2,SH3BP2,CCDC88A,SLC11A1,LIMCH1,WDTC1,SPTAN1,THSD1,ELOVL4,MCF2L,KCTD2,CDK20,KCNK12" Drug 224_DN retinoic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,ADD2,AK2,ALK,APBA2,GAS7,NCOA1,MYRF,BTRC,CLCN4,AATK,FEZ2,EDRF1,DYNC1I1,DRP2,SIDT2,EFNA3,EFNB3,EGR3,EIF4G2,COQ7,STX2,EFEMP1,FGFR1,TRMO,CYP46A1,RUNDC3A,GNAL,NCKAP1L,KCNJ10,LAMA2,MARK1,GIT1,NF1,SLC11A2,PCDH9,PLEC,FXYD1,PTHLH,GAL3ST4,CRTAC1,SUPT20H,FERMT1,ABLIM3,PPP4R3A,ARHGEF40,SIRT2,CDK5RAP2,SNCA,TROVE2,COBL,SSBP2,PLPPR2,ZNF23,ZNF32" Drug 7374_DN Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "BIN1,CDC42BPA,APC,MYRF,HOMER3,ARHGEF6,IQCK,CSNK1E,OSBPL3,PDE4DIP,CNTNAP2,KIAA0753,DLG3,EDNRA,FEM1B,SORBS3,COQ7,ZNF589,FER,TMEM8B,PRRC2B,GUCY1B1,RASSF8,MAN1B1,SYNPO,KHK,MAP4,MAPT,MBD1,GIT1,MT1M,PIK3R1,PLCD1,POLG,FSD1,RGS4,RGS10,ZNF671,SMARCC2,LIMCH1,WDTC1,KDM4C,NCDN,ELOVL4,TCF7L2,TIAM1,KCTD2,PARD3,UGT8,WNT7A,XRCC4,ZBTB14,MAP3K12,PRDM2,NT5M" Drug 2768_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AK2,C1QTNF3,OGT,CDC42BPA,MPDZ,MAGI1,CNOT8,TAOK2,CLCN3,SOCS5,PPP6R2,MAML1,HP1BP3,DSCAM,HIPK3,SORBS3,ING4,EML1,RRAGB,KAT8,ZNF589,FECH,FGFR1,INPP5K,MSL3,KCNH2,LSS,MMP16,NFYA,CNOT4,NUMA1,OPA1,PCDH9,PLEC,PMP22,ZSCAN32,RIPOR1,RGS10,EPN2,ZKSCAN3,ZCCHC24,SPTAN1,ITPRID2,VAMP1,PLCB1,PCDHA6,AP4E1,ZKSCAN5,PLPPR2,VGF,CLDND1,ZNF24,REEP1,UPF3A,UBE3B" Drug 3896_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "DPF1,ASIC1,BIN1,APAF1,KCNAB2,APC,APOC1,CACNA1I,CLDN10,SLC16A4,CDH2,ARHGEF6,DCAF4,NR1D2,C3orf18,VPS13B,LRRC17,RASGRP2,FER,ANKFY1,DPYSL4,PDLIM5,GAB1,GAD1,GAD2,GLYR1,MSL3,GPER1,IL11RA,KCNN2,L1CAM,SMAD1,MOBP,PFKFB2,PIK3CD,PLXNB1,LRP12,POU3F4,CEP41,PKIA,MAPK8,C1orf54,ZDHHC14,RPH3A,EPN2,FAM214B,RIMS1,ZC3H13,LMO3,ATP10B,NCDN,TRPC1,UCHL1,HPS4,SLC17A7" Drug 4366_DN Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "PLA2G6,LTBP4,APP,CDC14B,DNAH17,ARHGEF1,FOXN3,QKI,PICK1,CNTFR,TCEAL2,CSF1,CNTNAP2,DAPK3,HIPK3,EFNA3,FGF13,FGFR1,BAIAP2,SCARA3,C1orf61,SEMA4D,ALDH1L1,USP19,RUNDC3A,GLYR1,RAB30,GNAS,GPD2,TDRKH,ITIH2,KIT,LIG4,NOS1,LRP12,ELOVL2,TRIM68,ZNF821,RASA3,PPP1R9A,ASAP3,BTBD7,TSNAXIP1,TROVE2,PHLDB1,JMJD6,VPS13A,PLCB1,ATP11A,KIAA1107,ZEB1,CRTC1,FLRT2,ITM2C,NUP214" Drug 6284_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADD2,PLA2G6,MRTFA,OGT,PPFIA3,BMP7,SCAPER,CACNA1G,CA12,CBS,NEURL1,LHX2,WHRN,MICAL2,VCAN,PDE4DIP,CDON,TOM1,DUSP9,ABCC9,EDN1,MBNL2,AASS,LRRC23,STX2,CORO2B,FGFR1,EFCAB2,TMEM8B,POLL,STON1,LMO2,VWA5A,ADAM22,NF1,NOS1,NPPA,PTCH1,PTPRN2,RAB3A,RAB3IL1,GSTCD,RPS6KA2,DOCK10,SLC9A5,BTBD7,ZHX3,ARHGEF12,CRTC1,PCDHA5,CHST8,TK2,NR2E1,RIMBP2,VSNL1" Drug 4980_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "PPFIA3,SYNJ2,MTMR2,CFAP410,CACNA1D,CLGN,FOXN3,SLIT2,CLU,CNTNAP2,ARHGEF4,ZNF804A,DTNA,HIPK3,CELSR3,MBNL2,ING4,EZH1,KIAA1109,PRELID3A,SYT17,DISC1,MSL3,POLL,GRIK5,ELOVL5,IGSF1,VWA5A,MBD1,KITLG,NEK1,CNOT4,SERPINE2,PLCD1,SLC25A23,LRP12,GRAMD1C,SBF1,FNDC3A,SYBU,PREX2,PEX26,EPN2,RBM34,KDM4B,ZCCHC24,TROVE2,ASTN2,ROBO3,EXOC7,TMEM121,VLDLR,EVI5,ST7,UBE3B" Drug 6138_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "DOC2A,CDC42BPA,RGS11,SYNJ2,MYRF,CFAP410,CACNB4,HAP1,CHRNB2,SLIT2,NCAN,DCAF4,ARHGAP32,DGKG,PLPPR4,ATN1,HIPK3,OPTN,EIF1,STX2,ERBB4,FOXG1,AGAP2,CAMKK2,GCNT2,RUNDC3A,RND1,GNAO1,GRM8,MBP,MGAT3,MMP17,MYT1,TREM2,PCDH9,PDE1B,CAMKV,KLK6,FAM120C,RASGRF1,RFX2,SLC1A3,CXXC4,ZSWIM8,IZUMO4,ARHGAP26,TROVE2,AJAP1,EXOC7,TPM3,CHST5,UBE3A,VGF,MKRN3,SLC17A7" Drug 2720_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ACTN2,ADD2,BIN1,SEMA7A,APP,CDC14B,DNAH17,ZSCAN18,DDX3Y,GYG2,SGCE,MYRF,BTRC,CACNA2D1,CACNG1,CDH8,SLC4A7,CRY2,TMCC2,TENM1,FGFR3,FOXF2,ALDH1L1,GFER,RAPGEF1,ICA1,KCND1,KIFC3,KIT,MDM4,MGAT3,SCAMP5,PDE2A,FXYD1,PLP1,FA2H,MASP1,PTPRN2,CCDC40,SUSD4,RGS10,SYNDIG1,STUM,SYBU,RPH3A,SMTN,SORCS3,ZHX3,PHLDB1,MCF2L,CHST8,GPR161,TGFBR3,STMN4,FZD3" Drug 2698_DN "ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "RALGAPA1,NDRG2,AGT,C1QTNF3,TRMT9B,AMT,CDC42BPA,APC,APOC1,ASCL1,ASPH,RIPK1,MPDZ,NRP2,AKAP7,CX3CR1,ARHGAP32,DAPK3,BRINP1,TOM1,PLEKHA1,PTK2B,DLC1,ATP8A1,OGA,INPP5K,RUNDC3A,POLL,SPACA9,PADI2,TJAP1,KHK,MEF2C,MYO6,NF1,CNOT4,PDE4A,SERPINE2,FSD1,BCAS3,PTCH1,RIPOR1,CCDC92,URGCP,IZUMO4,SPTAN1,TSPYL2,RAP1GAP2,PLCB1,ADGRL3,TCF7L2,THRA,RBFOX2,TPM3,SSBP2" Drug 4077_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "SYN3,ADCY2,LTBP4,AMT,PKP4,APAF1,PPFIA3,AQP4,NRP2,SCAPER,TPP1,STOML1,CTNND2,DCAF4,CYBB,C2CD2L,DMPK,FRY,CAMSAP1,PRELID3A,GABRA2,GABRB3,SRCAP,GPR17,CACFD1,KLF12,IRF8,IL6R,MIA2,NDUFA5,NF1,NPR2,CLDN11,KCNK10,PFKFB2,PLCD1,POU3F4,PTN,RAB3IL1,GSTCD,RPS6KA2,SEMA6D,ZNF821,STUM,NTNG1,ZNF334,KIF13A,TNIK,ATP10B,PHLDB1,ARC,TBCEL,SYNE1,TNS1,NAV2" Drug 2177_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADCY6,BIN1,CDC42BPA,ANK3,PPFIA1,CDC14B,CDK10,ZSCAN18,CACNA1I,CFAP410,SYNGR3,REPS2,CLCN4,CNN3,PDE4DIP,DAPK1,SPOCK2,CTIF,MFAP3L,TRAPPC9,DSCAM,ING4,CEND1,C1orf61,AGAP2,FLT1,ERAP1,GRM7,PTGDR2,TJAP1,KCNJ5,KCNMA1,MAP4,MIA2,PDE4A,PPP2R2B,PRPH,WDR25,PTPRB,PTPRN2,ZNF821,SH3GL2,CPEB3,SHANK2,KDM4B,ATP10B,STX1A,SYN2,CRTC1,ATP13A2,CRB1,TK2,TPM1,CDK20,SLC30A3" Drug 5589_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ACTN2,KIDINS220,C1QTNF1,BIN1,APAF1,APC,CFLAR,CLGN,B4GALT6,ZFYVE9,CLCN3,NMT2,WHRN,GREB1,DAPK1,FBXL5,NTM,ING4,MTSS1L,IGSF6,PTK2B,SCML2,ZNF589,KIAA1109,TRAF3IP2,GLYR1,GNAS,KCNMA1,KCNN2,KHK,ADAM22,NEK1,NOVA2,PIK3CD,LRP12,MINDY2,MAPK10,PTAFR,PTH1R,C1orf54,KCTD17,ASIC4,SH3GL3,CPEB3,SLC9A5,SPART,ATP10B,DMXL2,RPGRIP1L,DNAH7,TMPO,FLRT2,LAT2,SLC17A7,JPH3" Drug 3727_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ACTN2,ADD2,LTBP4,APP,CDK10,NRP2,CHI3L2,CHN2,CLCN4,SLC24A2,CNTFR,IFFO1,CNTNAP2,NOS1AP,DAPK3,CTIF,RABGAP1L,DTNB,ECM2,EDNRB,PLXNC1,MTSS1L,KAT8,FGF12,CAMKK2,RND1,GPD2,GPM6B,ICA1,KCNJ5,KCNQ3,MDFI,TM6SF1,NFYA,PDE2A,PTPRN2,GAL3ST4,RGS4,STK32B,RXRA,FBXO11,FNDC3A,PEX26,ARHGEF40,SLC11A1,SLCO1A2,ARC,ADGRL3,RPGRIP1L,THBS4,TPM3,ZMYND8,KCNAB1,FZD3,RNF146" Drug 3562_UP D-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NME5,PPFIA4,ATP1A3,ATP2B2,MTMR3,CACNA1I,MYRF,SLIT2,TPP1,HOMER3,WHRN,SUSD5,PDE4DIP,DOCK4,RIMS3,MFAP3L,MAGI2,SPOCK3,SEMA3D,EFNB3,EN2,RASGRP2,ZNF589,FGF1,CAMKK2,GPR153,SEPT9,RND1,GLRB,GRIK4,GRM8,KLF12,KCND3,KHK,ZNF862,SLC25A23,C19orf57,PRODH,PRPH,ZSCAN32,PTPRB,PKNOX2,SORCS3,CDK19,SYN2,KAZN,TBCEL,TCF4,SZT2,SLC35G2,HIF3A,TIMP4,ICAM5,NT5M,SLC17A7" Drug 4668_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,NR0B1,APBB1,KIF1A,ADGRB2,NRP2,NEURL1,SEPT7,LARGE1,MAGI1,EPS15L1,STOML1,PICK1,RCHY1,CSF1R,NOS1AP,SEMA3D,ETV1,ABCA8,FGFR1,FYB1,SIGLEC8,ATP8A2,GLYR1,GPR75,STON1,CACFD1,PADI2,KCND3,KIFC3,LAMA2,VWA5A,PACRG,NCAM1,PDGFRA,PHKG1,RETREG1,MINDY2,PROX1,CNNM2,PTPRN2,CCDC40,ENOX1,RFX2,RGS12,MYH14,SYNDIG1,RASA3,SLA,ARHGEF40,COBL,EXOC7,RPGRIP1L,THRA,REEP1" Drug 4192_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "DDO,CDC14B,CCDC181,BACH1,BSN,CACNA2D1,ARHGEF2,WHRN,IFFO1,NCOR2,ARHGEF10,PDE4DIP,CNTNAP2,MAML1,SPOCK2,ST8SIA3,TNK2,EFS,PIPOX,CORO2B,GAD2,GNAL,HPSE2,KCND3,KCNJ5,MAP2,MAPT,AFDN,CNOT4,NPTX1,NUCB1,PDE4A,PFKFB2,ZSCAN32,FAM120C,RFX2,RGR,ROM1,FNDC3A,DZIP1,PREX2,OGDHL,SNCA,TSNAXIP1,ZSWIM8,IZUMO4,RBM26,ARC,PCDHA5,TLR4,SEZ6L,TPM1,TRPC3,VSNL1,KCNK12" Drug 2934_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABAT,NDRG3,NDRG2,ALAD,MARCH3,N4BP2L1,BACH1,CAST,SPAG9,KRIT1,SLC16A4,CD86,SOCS6,ZFYVE9,NMT2,RABGAP1L,RCAN1,ABI2,LPAR6,ING4,LRRC23,RRAGB,ZNF589,FER,TRMO,CINP,TXNL4A,LPAR4,IRF8,JAK2,KPNA5,MDM4,GPR85,RETREG1,STRN3,PRKAB2,ZSCAN32,ZDHHC14,PPM1E,ZKSCAN3,ZNF667,TMCC1,KDM4B,KDM4C,KIF1B,ZBTB43,CEP68,JMJD6,TCF7L2,AP4E1,TPM1,MAP3K12,PRDM10,KCNAB1,PHTF2" Drug 4318_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AK2,PLA2G6,C1QTNF3,MRTFA,PKP4,APBB1,ASPH,ATM,N4BP2L1,ATP6V0A1,ADAM23,CFLAR,FOXN3,ZFYVE9,AKAP5,CRY2,SRGAP3,IRAK4,ETV1,FGFR1,SCARA3,TMEM8B,POLL,CACFD1,HSD17B1,ICA1,IL6ST,KIF5C,LYRM9,CNOT4,NTRK2,PDE3B,GPR85,PENK,MAPK8,SNRK,C1orf54,RAP1GAP,COA1,TSNAXIP1,ARHGAP26,SPTB,ZBTB43,LHPP,MAPK8IP3,MLC1,EXOC7,PCDHA5,SLC44A1,TK2,R3HDM1,ZMYND8,VIPR2,SPHK2,KCNAB1" Drug 3064_DN Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "BRAP,BIN1,APAF1,DNAH17,ASPH,KSR1,SYNJ2,HIP1R,CDC42,FOXN3,CHRNA4,ZFYVE9,CLCN4,STOML1,CREM,TM9SF4,EXOG,HIPK3,ABI2,PLXNC1,ING4,VPS26C,F5,KIAA1109,OGA,GAB1,ALDH1L1,SRCAP,CRCP,GNG4,LILRA2,DIDO1,LIG4,AFF1,NF1,NNAT,RETREG1,PLEC,RASA3,SH3BGR,SLC2A5,SLC20A2,MAPKBP1,SNCA,TNIK,SYT5,ATP11A,TRIM2,TLR4,TPM1,CDK20,TRPS1,CLIP2,PHTF2,SSPN" Drug 3937_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ARHGDIG,ADAM23,ADGRB3,CACNB2,HAP1,SLC16A4,KCNAB3,CDH10,CDO1,RAB33A,LY86,WHRN,DCAF4,DNAJC6,HP1BP3,TRAPPC9,HIPK3,ELN,ETV1,FABP7,PTK2B,ZNF589,KIAA1109,FHL1,AFF2,GAP43,GFAP,GRM7,AP4S1,ICA1,IGF1,LIFR,TM6SF1,KITLG,NTRK2,CDIP1,CEP41,PKN2,KLHL11,SCN8A,STUM,RASA3,FBXO11,ST6GAL1,SLC1A2,HECW1,ATP10B,INKA2,ABCC8,TAC3,TCF4,DMXL2,HIF3A,KCNAB1,DPF3" Drug 4078_UP "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "DPF1,AP2A2,ZSCAN18,ATP2B2,ATP2B3,BCHE,FUBP1,MTMR3,CACNA2D1,HAP1,RUNX1T1,SCARB1,CACNA2D2,RAB33A,PLAA,TPP1,SULT4A1,PICK1,IFFO1,HAPLN1,RGS6,RIPOR2,SPOCK2,MAGI2,SPOCK3,ARNT2,EDIL3,EDNRA,MRNIP,PIPOX,CACNG2,AGAP2,IQGAP2,GRM7,IL6R,KCNN1,NF1,PBX1,PDE4B,PTAFR,RNASEL,STK32B,EMID1,ZNF821,ASAP3,NTNG1,SLC2A5,RIMS1,SOX10,IZUMO4,RBM26,VAMP1,PCDHGA1,NPL,SPHK2" Drug 6456_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AK2,PLA2G6,SEMA6A,SRPX,APBA2,EPB41L5,BCAS1,APP,CDC14B,ALDH4A1,SLC4A4,STX16,ADAM15,RAB29,ARHGAP33,HINFP,SIPA1L1,PDE4DIP,GIT2,DBT,DNM2,FEM1B,CNNM1,EFNA3,PLEKHO1,COQ7,DENND4A,CDKL3,GLS,TDRKH,GPER1,GPR37,MAP4,MAPT,LYRM9,NCAM2,NF1,P2RY1,WLS,ZNF821,CXXC4,LIMCH1,SPART,TROVE2,THSD1,ASTN2,SEMA4A,EXOC7,FBXW11,TMOD1,RBFOX2,VAV1,VLDLR,KLC2,HPS4" Drug 4607_UP Dimethadione [695-53-4]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "CADM3,KSR1,CACNA1G,CFAP410,CACNG1,KRIT1,CHGA,FAM149A,GAL3ST1,SH2B1,CSF1,VCAN,PPP1R16B,BRINP1,MFAP3L,SEMA3D,SIDT2,EBI3,EGFR,ERBB4,TBR1,DKK3,PRUNE2,GRIK2,GUCY1A2,ICA1,IL6ST,KCNJ4,KCNJ10,ADAM22,MYT1,SNTG1,PDE3B,SNRK,PTH1R,C1orf54,PRR5L,MRAS,DZIP1,ANKRD6,SLC4A3,SLC1A7,SOX15,ATP10B,INKA2,COBL,TMOD1,SEZ6L,LILRA4,TRPC1,AMOT,VIPR2,ZIC3,SEMA3B,EPM2A" Drug 4084_DN Moxonidine [75438-57-2]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ASIC1,C1QTNF1,APBB2,PPFIA3,SHROOM2,MARK4,NCOA1,ST3GAL5,BAIAP3,BTRC,KRIT1,CBFA2T2,TAOK2,DNAJB5,CNTFR,WHRN,AKAP5,CDC42BPB,CSF1,SLITRK5,GPRASP1,CTIF,MFAP3L,COQ7,DENND4A,ZNF549,CDKL3,DLC1,SEMA4D,SORBS1,B4GALNT1,GNAL,TDRKH,GPER1,ICA1,MYT1,NOVA2,CDIP1,RALGDS,RGS10,MYH14,GSTCD,RPS20,AMBRA1,SLC1A7,PREX2,ARHGEF40,SMARCD3,WDTC1,PCDHGA10,THRA,R3HDM1,KLC2,EVI5,GAN" Drug 3978_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "C1QTNF1,BIN1,APAF1,KCNAB2,CDC14B,ATP1A2,FGF17,NRP2,KALRN,SEPT7,CLGN,ZFYVE9,WHRN,AATK,GSDME,SPOCK3,SRGAP3,DRP2,ABCC9,REEP2,FHL1,FOXG1,NEU3,LYVE1,POLL,PCLO,GRM8,AP4S1,SHISAL1,KCNJ3,MEF2C,MMP16,CAMKV,MASP1,PTAFR,PTPRH,RASGRF1,KHDRBS2,RNASE1,KANSL3,ARHGEF40,NMNAT2,IZUMO4,NPAS3,DOCK9,HEY2,TMOD1,LILRA4,TRPM2,MICAL1,BEST1,SLC13A3,ZNF711,ADAMTS9,MVB12B" Drug 4116_UP Cefotetan [69712-56-7]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ACTN2,PRX,MARK4,N4BP2L1,NRP2,CACNA1G,CALB1,USP2,MTMR7,ARHGEF2,LHX2,WHRN,MYRIP,RIMS2,TMCC2,CDON,EDN3,EDNRB,FAM13A,EGFR,PLXNC1,TENM1,TNK2,LRRC17,RASGRP2,EPHB1,NRN1,FAM198B,OLFM1,PDLIM5,OGA,GABRA2,SRCAP,PTGDR2,KCNN1,VWA5A,MAPT,NEUROD2,OPCML,CLDN11,PPARA,PTPRB,C1orf54,TRIM68,SLC1A7,SLC2A5,SLC11A1,PEG10,TACR1,SYNE1,RALYL,PIK3R5,TRIO,SLC30A3,SSPN" Drug 6626_DN Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AP2A2,TRMT9B,APC,SEMA4G,MYRF,CFAP410,CBFA2T2,STOML1,AATK,CNTNAP2,DZIP3,DCAF4,RIMS3,CTIF,KBTBD11,TNK2,ZNF549,TUBB4A,BAIAP2,TRAF3IP2,GAD1,LPAR4,SYNPO,IFI16,SCIN,MAPT,MBD1,AFDN,LYRM9,MAPK7,PTPRE,PTPRH,RIPOR1,ZCWPW1,TTLL7,MYH14,BCAN,EPN2,FAM214B,SMARCC2,WDTC1,DDN,TROVE2,MAPK8IP3,SYT11,JMJD6,ASTN2,KIAA1107,SMG6,RPGRIP1L,ARHGEF12,TPM2,TRIO,LMF1,NAV3" Drug 6601_UP Retrorsine [480-54-6]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADD1,NR0B1,GAS7,APOC1,ATP2B3,CADM3,CFLAR,CACNA1G,CACNA1D,CACNG1,DGKI,CDH10,TAOK2,ENTPD4,ARHGEF10,VCAN,CNTNAP2,MFAP3L,SRPK3,PIPOX,FAM198B,AGAP2,SIGLEC8,GNG3,GRIK5,IL1RAPL1,GUCY1A2,FAM107A,IRAK3,ICA1,SHISAL1,PACRG,NF1,NOVA1,PRKAR1B,MAPK10,PTPRB,C1orf54,SUSD4,KHDRBS2,NEK11,IL17RB,MRAS,SLC8A1,SPTB,ZEB1,TIMP4,SEZ6L,TPM1,AMACR,ZNF74,SLC17A7,KCNAB1,EPM2A,DPF3" Drug 3339_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADORA1,GAS7,CDK13,SLC4A4,ATP2A2,ADAM23,CFLAR,CACNA1I,LDLRAD4,CFAP410,SLC16A4,CHRNB2,ARHGEF6,TCEAL2,PLCH2,MBNL2,EPHB1,FAM198B,FABP7,ACSL4,ATP8A1,KIAA1109,FHL1,DISC1,RND1,GPR37,NXPH3,ICA1,IL6R,KCNJ4,MOBP,NPR2,PDE3B,C19orf57,CNTLN,ACSM5,RAD52,C1orf54,RASGRF1,TRIM68,RGS10,RASA3,ASAP3,SLC1A7,CCDC88A,COA1,OGDHL,WDTC1,ZC3H13,SPTB,SYT11,GPR161,NT5M,EVI5,MVB12B" Drug 5803_UP Propidium iodide [25535-16-4]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADORA1,NME5,GAS7,ARSE,KIF1A,NRP2,BMP7,BTRC,CACNA1D,INA,CHN2,NRXN2,STOML1,HOMER3,COL9A2,ARHGEF10,RIMS2,ARMCX2,RABGAP1L,DSCAM,EDIL3,FRY,ING4,OLIG2,MTSS1L,ANKMY1,HPCAL4,GABRA2,SYT17,GATM,SPACA9,ATXN2L,ITIH2,JAK2,LAMA2,LSS,AFDN,MMP17,CTNNA3,PDE3B,PDE4A,PLP1,PPP2R2B,PTPRB,PID1,CCDC40,ENOX1,RGS12,DZIP1,SLCO1A2,IQSEC2,CRB1,SEZ6L,LAT2,KCNAB1" Drug 2494_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "SLC12A5,AGT,FAM135A,AMPH,BIN1,SEMA7A,PPFIA3,LGR5,PTCH2,ALDH4A1,KIF1A,KSR1,BMP7,CACNA1G,MAP7,CDC42,TAOK2,SLIT2,CREM,HIPK3,MBNL2,RASGRP2,KHDRBS3,GPR162,GPD1,GPD2,ATF7,GPR22,KIF3A,GUCY1A2,SCIN,KCNQ3,LAMA2,NEFM,NF1,NINJ2,CCSER2,POU3F2,PLPPR1,SBF1,BCAN,BTBD3,SLN,MAPK8IP3,PHLDB1,ACSBG1,WSCD1,ATP13A2,RIMBP2,FLRT2,PRDM2,SLC17A7,KCNAB1,FAM13C,SSPN" Drug 4751_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ARID1A,NDRG3,BIN1,AMT,BTRC,CA4,CLGN,FOXN3,FADS2,NCOR1,MAML1,MFAP3L,C2CD2L,DSCAM,DTNA,EDNRA,EIF4G2,SORBS3,F3,ACSL4,ZNF589,BAIAP2,AFF2,PDLIM5,FAM49B,GNAS,GPD2,MAP4K5,INPP1,KITLG,MITF,KCTD15,MINDY2,PRKAR1B,ELOVL2,PEX5,SBF1,COA1,RBM34,TROVE2,CAMTA2,VPS13A,PLCB1,EXOC7,IQCE,TCF7L2,PSD3,PCDHA5,BEX4,TNS1,PLPPR2,VGF,SPHK2,PRDM2,EVI5" Drug 5874_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "C1QTNF1,TRMT9B,APC,RGS9,BMP7,CAMK2B,CACNA2D2,CHI3L2,ASIC3,JAM2,ARHGAP22,CLCN4,TPP1,PICK1,COL9A3,JAKMIP2,MYEF2,PARD6A,KBTBD11,ATN1,SIDT2,EFNB3,HSD17B14,TUBB4A,FGF1,FGF12,CAMSAP1,PRELID3A,TMEM8B,GLYR1,POLL,GPD2,CNTRL,ICA1,MDFI,ADAM22,ENPP2,PLCD1,PLP1,MAPK10,KCTD17,NEK11,FBXW7,FNDC3A,RPH3A,SLC1A7,PKNOX2,SMARCD3,WDTC1,SMG6,SLC44A1,LILRA4,PARP6,STMN4,MPPE1" Drug 7071_UP CAY10397; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "BIN1,PPFIA3,CDK13,ASPH,EIF4G3,CFAP410,NMT2,STOML1,QKI,PDE4DIP,KLHL3,PARD6A,SORBS3,ING4,MRNIP,BAIAP2,FOXG1,TRMO,SORBS1,ERAP1,SYT17,SRCAP,GPER1,SHISAL1,KIF5C,MDFI,SCAMP5,MN1,TAGLN3,SETD4,PC,FA2H,MED1,GON4L,SNRK,PTPRN2,SUGCT,TCP11L1,ASAP3,SLC20A2,ZNF667,SMARCD3,KDM4B,SPATA7,SPTAN1,CAMTA2,KAZN,TCF4,SZT2,PSD3,ARHGEF12,FAM155A,MICAL1,AAAS,GAN" Drug 7425_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABR,KIDINS220,AP2A2,AK2,ALCAM,FAM131A,APP,RIPK1,ADGRG1,CLTB,DCAF8,C2CD2L,MED12,ATN1,SEZ6L2,EDNRA,CELSR3,SORBS3,DMTN,BAIAP2,C1orf61,SEMA4D,SEPT9,SRCAP,HMGB1,DHX35,NEK1,NFYA,ODF2,PLXNB1,PRKAR1B,PRODH,WDR25,TMEM231,GTDC1,RGS10,RPS6KA2,FUZ,SLC6A8,BTBD7,KDM4B,WDTC1,ZBTB43,PHLDB1,PLCB1,ATP11A,CABIN1,LMF1,NDRG4,UPF3A,PCBP4,WIPF2,MPPE1,ST7,KAT6A" Drug 6561_DN STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "RALGAPA1,ASIC1,C1QTNF1,OGT,SHROOM2,CFLAR,BTRC,AP4M1,FADS2,IQCK,COL9A2,PREPL,RIMS3,DBT,MAMLD1,SIDT2,HSD17B14,ERCC2,PRKAG2,FHL1,TRAF3IP2,DENND2A,GAD1,HBS1L,SIGLEC8,INPP5K,GLS,GPM6B,GPER1,HNMT,MEIS1,MXI1,NOVA2,PC,SSH1,PTN,RAB3A,FAT4,SUPT20H,SCG5,ST6GAL1,SLC22A4,KIF13A,TMCC1,TNIK,CEP68,TK2,CABIN1,TNS1,TPD52,ZKSCAN5,XRCC4,WNK1,MPPE1,DPF3" Drug 5407_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "KCNAB2,CACNA1G,BAIAP3,CALB1,NEURL1,FOXN3,CLCN4,CSF1,RIMS2,RIMS3,EFNB3,CORO2B,FHL1,PRELID3A,NR3C1,NXPH3,ITIH2,ITPKB,KCNN1,VWA5A,MAP4,MOBP,MPP2,MSR1,CNOT4,PENK,PLCD1,LRP12,NECAB2,POU3F2,PPP5C,CEP41,MAPK7,PTAFR,NKAIN1,RAD52,WLS,SEMA6D,SH3BP2,SLC1A7,SHANK2,SLC14A1,SNCA,SOX2,TSNAXIP1,KDM4C,SAMSN1,MAPK8IP3,SYT11,KIAA1107,ZEB1,PCDHA3,TRPM2,ADAMTS9,KCNAB1" Drug 6688_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "LTBP4,APC,ATM,NRP2,IL33,CACNA2D1,SCARB1,ADGRG1,CLCN4,RCHY1,HAPLN1,PHF14,TBC1D5,HIPK3,EFNA3,EPB41,ETV1,ZNF589,FGFR1,EFCAB2,GAB1,SIGLEC8,GRIN1,GRM1,ATXN2L,ICA1,ITPKA,LSS,MDM4,MYCN,CNOT4,PDGFRA,ABCB1,PLCD1,MINDY2,PPP5C,GDPD2,ZSCAN32,PTPRB,RGS3,RPS20,TMEM156,SFPQ,SLC6A9,SLC15A2,FAIM2,TNIK,ARHGAP26,ASTN2,DOCK9,PCDHA5,GPR161,ZMYND8,ZNF24,PHTF2" Drug 1530_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABHD6,SEMA6A,ALCAM,TRMT9B,APBB2,APC,APOC1,MARK4,ATM,EIF4G3,CADM3,SYNJ2,CFAP410,SEPT7,CDH8,DNAJB5,HOMER3,AKAP7,ENTPD4,NCOR1,EDRF1,DGKG,GIT2,ATN1,EFNB3,EIF4G2,NCALD,FGF13,FGFR1,FOXG1,DCTN2,PDLIM5,MSL3,NXPH3,IL6ST,ITIH2,MBD1,MN1,NNAT,SLC25A23,ZSCAN2,ZFHX4,RPS6KA2,NLGN1,ZNF365,SLC2A5,SLN,ZCCHC24,SPART,DIP2A,SLC44A1,HIRA,ZIC3,WNK1,EPM2A" Drug 4152_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "APBA2,CDC14B,ATP1A2,CACNG1,LDB2,CLCN4,AKAP6,VCAN,CTH,CYBB,TOX,SPOCK3,DMD,DMPK,SGK2,KCNMB2,EFS,SPEG,SCML2,ATP8A1,NSG1,OGA,ZNF44,PCLO,GUCY1A2,ICA1,TJAP1,ITGA7,KCNMA1,MEF2C,MYH7,MYO9A,NTRK2,PPP5C,APTX,PTCH1,ENOX1,RPS6KA2,STUM,ST6GAL1,KDM4B,PDZD2,IQSEC2,CDK19,RBM26,MAPK8IP3,FAM168A,SYN2,PCDHGA10,PCDHGA1,HIF3A,TEK,R3HDM1,LAT2,NT5M" Drug 3686_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "APBB1,APC,RASL11B,ALDH4A1,EIF4G3,CFLAR,SYNJ2,SCAPER,CFAP410,SYNGR3,ARHGEF2,CDC42,LARGE1,PLEKHB1,TAOK2,PICK1,IRAK4,ANKMY1,FGFR1,SORBS1,GAD2,GLS,GPR17,KCNJ5,KHK,MAPT,PIK3R1,GRAMD1C,CNNM2,CNTLN,RGS4,RGS10,NEK11,TCP11L1,ZNF821,ZFP30,ASAP3,DZIP1,SLC1A7,SLC20A2,ZNF667,ZNF415,IQSEC2,CDK19,LHPP,TROVE2,SS18,SYT11,TPM2,RPRM,LMF1,WIPF1,NSD2,XRCC4,SH3GLB2" Drug 601_DN MK-886; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ACTN1,ADCY2,SRPX,BIN1,AMT,CDC42BPA,ANK2,APC,APP,ARNTL,PDE8B,MARCH3,ATP2B1,BMP7,INA,CDH2,ENTPD4,ARHGEF4,GIT2,SRGAP3,DPH1,RCAN1,LRRC23,KIAA1109,FGFR1,MALT1,GRM1,ADAMTS6,KIFC3,VWA5A,MAP2,MYT1,PIK3R1,STRN3,PRRX1,MINDY2,PPP2R2B,RELN,PLPPR1,RNASE1,TMEM206,SBF1,ZNF821,ITSN1,FAM214B,SMARCC2,IGSF9B,BEX1,VAMP1,COBL,TNS2,CRTC1,ZNF34,PARD3,RPRM" Drug 2140_UP Seneciphylline [480-81-9]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABHD6,C1QTNF3,MRTFA,APAF1,CASK,ARHGDIG,ATP6V0A1,QKI,ABI3BP,CREM,CSNK1E,VCAN,DLG4,EFNA3,OLIG2,SCML2,GALC,ADAM28,ZNF276,GPR19,PADI2,ATXN2L,KCNJ5,KHK,MAP4,TM6SF1,TAGLN3,NNAT,PFKFB4,PTPRN2,FAM120C,RIPOR1,ZCWPW1,RGS12,RXRA,SALL1,ZCCHC24,SOX15,KDM4C,SPTAN1,CEP68,ARHGEF9,CAMSAP2,TBCEL,TCF7L2,ARHGEF12,ATP13A2,AP4E1,RUNDC3B,ZMYND8,LMF1,VSNL1,KLC2,MAP3K12,FZD3" Drug 2490_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABAT,ARID1A,AGT,ATP2B2,LDLRAD4,CAMK2B,MAGI1,CDO1,CACNA2D2,CHI3L2,CABP1,CREM,DNAJC6,DCT,CNIH3,MAGI2,SPOCK3,TMCC2,DLG3,SHANK1,TOM1,OPTN,CDKL3,FOXG1,AGAP2,AFF2,CAMKK2,SIGLEC8,STON1,GPR22,GRIK5,GPR45,HNMT,IL6ST,KCNJ5,MAPT,MDFI,MEF2C,SLCO1C1,NPPA,OMG,GDAP1L1,STRN3,PPP2R2B,VPS13C,PPM1E,RBM34,ZC3H13,NPAS3,LHPP,MAPK8IP3,SEPT8,SYT5,OBSL1,SEZ6L" Drug 3579_DN Kaempferol [520-18-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AK2,DOC2A,CDC42BPA,APBA2,APC,CDC14B,PLA2G4C,ASPH,CFLAR,BTRC,CACNB2,SULT4A1,ABI3BP,ENTPD4,SH2B1,MFAP3L,LYPD1,RABGAP1L,DLG3,EDNRA,ENO2,STX2,ATP8A1,BAIAP2,FAM49B,GPR37,NR3C1,BTN2A1,KITLG,NEK1,NF1,NFYA,SLC11A2,PCDH9,MAPK8,LRRC49,NKAIN1,NLGN1,FAM214B,SLC6A8,CCDC88A,ELMO2,SPART,SS18,ST5,PCDHGA10,SLC44A1,TMPO,RUNDC3B,ZBTB14,REEP1,EVI5,URM1,KAT6A,AAAS" Drug 5665_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,LTBP4,CDC42BPA,APBA2,ADGRB3,CACNA1I,HIP1R,MAGI1,CACNA2D2,SLIT2,FADS2,RASSF2,INTS1,DCT,DSCAM,ECM2,TNK2,ELN,LRRC17,EFS,CACNG2,ZNF589,FGFR1,CAMSAP1,KHDRBS3,GPR37,GRIK2,ATXN2L,HLF,HPSE2,TJAP1,KCNH2,KCNMA1,PACRG,MEF2C,ADAM22,MYBPC1,P2RY1,TREM2,PDGFRA,PFKFB2,PACSIN1,PTAFR,ZNF493,KLHDC8A,CARF,KCNIP2,SH3BP2,SAMSN1,ZC4H2,PCDHGA1,DICER1,VLDLR,SPHK2,PARP11" Drug 22_DN 1-phenylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "NDRG2,AK2,AMPD3,APBA2,PDXK,ASCL1,DNAH17,CADM3,CALB2,CAPN3,CCNT1,P2RX6,CBFA2T2,SCARB1,JAM2,CNTFR,NCOR1,DPP6,TSPAN5,SIDT2,OPTN,EFNB3,ETV1,FGF1,FGR,PCYOX1,GLS,FERMT2,PCLO,GRIN1,BTN2A1,PTPRT,FAM107A,RASSF8,ELOVL5,IGSF1,AFF1,MYO7A,NUCB2,PDE1C,NLE1,PRODH,PTCH1,SUSD4,RNASE1,ZFP30,SLC11A1,SNCA,NMNAT2,MYCBP2,TAL1,TBL1X,SLC19A3,UCHL1,LAS1L" Drug 4408_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ALCAM,AMPD3,APC,APLP1,APP,CDK10,MTMR3,CA4,CBFA2T2,CDC42,CLCN3,SLC4A7,CSNK1E,RIMS2,DBN1,EXOG,SLC12A6,OPTN,ERCC2,F3,FGF13,FGFR1,BAIAP2,FOXG1,PDLIM5,KHDRBS3,GAD1,SEPT9,SRCAP,RUNDC3A,GNG4,CNTRL,GRM8,TJAP1,IL6ST,KCNH2,KHK,MOBP,ADAM22,LRP12,MAPK7,MAPK8,CNNM2,ZDHHC14,EMID1,ASAP3,SLC9A5,PDZRN3,PHLDB1,TIAM1,VLDLR,SPHK2,SYNC,EMSY,SSPN" Drug 2992_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "RALGAPA1,AMH,ANK2,BMP7,CACNA2D2,CLCN4,SEC31B,CREM,RGS6,PDE4DIP,DZIP3,SMG7,EXOG,ABCC9,EDN3,ELAVL3,SRPK3,DMTN,EFS,CACNG2,GABRA5,GAD2,NEU3,GFER,GPR22,SPACA9,HPSE2,HTR2A,KCNC1,AFDN,MMP16,MSI1,ADAM22,MYCN,NCAM1,NEUROD2,OXTR,PILRA,RELN,CNNM2,RGS12,NEK11,CPEB3,SLC1A6,RPH3A,LHPP,ELOVL4,ROBO3,TPM1,TPM3,FLRT2,CLIP2,KLC2,KCNK12,SLC17A7" Drug 3413_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "SLC12A5,C1QTNF1,SEMA6A,BEGAIN,TRMT9B,BIN1,GAS7,PDE8B,ADAM23,SGCE,BTRC,HAP1,CLGN,FOXN3,ABI3BP,CSF1,DCAF8,JAKMIP2,PLXNC1,C3orf18,HSD17B14,VPS13B,IGSF6,SCML2,FGFR1,FYN,SRCAP,AHDC1,ITIH2,ITPKA,KCNJ5,LSS,MBD1,MSI1,NPPA,PDE3B,PLCD1,PTN,RGS3,RGS12,RASA3,SLC1A7,SMTN,SNCA,RBM34,ANKRD12,KAZN,CRTC1,TK2,PIK3R5,UBE3A,VAV2,VLDLR,SPHK2,NUP214" Drug 6449_UP Rolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADORA1,BEGAIN,APBB2,PPFIA3,PRX,ATP1A2,SCAPER,HAP1,CDH8,CHI3L2,CHRNB2,TPP1,QKI,WHRN,COL9A3,NRG2,NCOR2,RGS6,CTH,DAPK1,CTIF,SGK2,LRRC17,NRN1,F5,ATP8A2,PCDH17,GPD2,NR3C1,GUCY1B1,JAK2,KCNMA1,KIF5A,MAN2A2,CNOT4,ENPP2,CAMKV,LRRN3,RALGDS,SUGCT,CNKSR2,KANSL3,COA1,LIMCH1,KIF13A,ZNF415,ACSBG1,POPDC3,DMXL2,PCDHA6,KCNK12,SLC30A3,PRDM10,KCNAB1,ADAMTSL3" Drug 482_DN celecoxib; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "RBM10,KDM5D,ADD2,LTBP4,GAS7,ARHGDIG,ARNTL,MPDZ,CD38,NEURL1,KCNAB3,JAM2,TAOK2,LHX2,PDE4DIP,GIT2,DCC,SPATA2,DSCAM,FEM1B,SIDT2,EFNA3,EFNB3,RCAN2,RASGRP2,FCGRT,CAMKK2,NSG1,GAD1,GJB1,TXNL4A,NCKAP1L,VSIG4,KCNC1,KCND3,KCNK2,ADAM22,NTRK3,C19orf57,MAPK8,CNNM2,KHDRBS2,GSTCD,FUZ,KBTBD4,EMC1,SPTB,ANKRD12,TMEM151B,CRTC1,TNS1,SEZ6L,ZNF142,KCNAB1,MVB12B" Drug 3786_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "LTBP4,DOC2A,SLC4A4,ALDH7A1,ADGRB2,BCHE,BMP7,CBFA2T2,CHM,NRXN3,CLCN4,STOML1,AKAP7,IQCK,AKAP5,CRMP1,DAPK3,MFAP3L,TRAPPC9,CELSR3,LPAR6,EPHA5,ETV1,F5,FGF1,FGFR1,DCTN2,SIGLEC8,USP19,ZNF276,MSL3,GRM1,MN1,NF1,NOVA1,NTRK2,PALM,EPN1,PRPH,GON4L,CCDC40,GAL3ST4,TCP11L1,SH3BP2,SLC1A7,FAM214B,SMARCD3,UNC5B,DDN,ARC,WIPF1,SPHK2,NT5M,SLC17A7,KCNAB1" Drug 3090_UP Altretamine [654-05-6]; Up 200; 19uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ABHD6,ADCY6,KIDINS220,MTUS1,KCNAB2,BCAS1,AQP4,CASK,ARRB1,CCDC181,CACNA1I,SLC16A4,SEPT7,ZFYVE9,STOML1,CNN3,CREM,CRMP1,ABCG1,PLCH2,CTNND1,CNIH3,SORBS3,C3orf18,EPB41,STX2,ETV1,EYA1,PTK2B,DCTN2,ERAP1,POLL,GPR22,SPACA9,PRDM5,HRH3,ITIH2,KCNF1,MAP4,MBNL1,MSI1,NAP1L2,CNOT4,PDE1C,MTRF1L,ZSCAN32,RAB3IL1,ZMAT4,ASIC4,ST6GAL1,TBCEL,PCDHGA10,TNS1,GDPD5,KCNAB1" Drug 3742_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "BRINP2,SLC4A4,ATP2A2,KIF1A,NRP2,MYRF,CACNA1A,CACNB2,CHRNB2,ARHGAP22,ZFYVE9,ABCG2,IFFO1,NRG2,CRY2,NCOR2,MFAP3L,DTNA,EDNRB,RBM12,ELAVL3,ETV1,FGFR1,C1orf61,RAB30,GPM6A,TDRKH,GRM7,ITGA7,ITIH2,KCNJ5,MAN2A2,MARK1,ADAM22,PDE3B,PDE4A,CEP41,ZSCAN32,KCTD17,RNASEL,SMARCD3,IZUMO4,SPTB,DDN,MLC1,VAMP1,IQCE,SMG6,AP4E1,DAAM2,TRIM9,SPHK2,REEP1,EVI5,KCNAB1" Drug 1508_DN Glipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AP2A2,GAS7,APP,ALDH4A1,ATM,CFLAR,CAMK2G,ZFYVE9,QKI,PICK1,SH2B1,DAPK3,GIT2,SLC12A6,DTNA,TSPAN5,HIPK3,SUGP2,SORBS3,FER,FAM49B,OGA,ERAP1,AHDC1,GLS,KCNMB4,CACFD1,ATXN2L,MBD1,NOS1,CNOT4,PDE3B,POLG,MINDY2,PRKAR1B,MAPK8,GON4L,ROM1,TCP11L1,PEX26,EPN2,SMARCD3,LIMCH1,IQSEC2,NCDN,AP4E1,HEY2,HIRA,PLPPR2,VIPR2,XRCC4,SPHK2,EMSY,KCNAB1,SSPN" Drug 4305_UP Solasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "SYN3,APAF1,PPP4R4,PTCH2,ATP1A3,ADAM23,AZGP1,BMP7,CDK5R2,CBS,ADGRG1,CHRNB2,NRXN3,CNR1,COL9A1,CSF1,ATRNL1,PLCH2,CNTNAP2,PHYHIP,CTIF,HS3ST2,ATN1,EDNRB,OLFM1,DPYSL4,PRELID3A,SEPT9,MYOZ2,SOX21,KCNQ3,SHC3,MYT1,NNAT,NOVA2,NPTX2,NTRK2,P2RX7,RETREG1,CEP41,PRKAR1B,PTAFR,RGS3,PNMA8A,PKNOX2,SHANK2,SNCA,IQSEC2,LMO3,ATP11A,TAL1,TNS1,TPM1,TRPC1,SLC17A7" Drug 2129_UP Retrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ALK,BIN1,ANK3,PPFIA4,APAF1,FAM131A,APP,AQP6,SEMA4G,KIF1A,NRP2,CDH8,DNAJB5,PICK1,ABCG1,SPOCK2,BRINP1,HS3ST2,ABCC9,EEF1A2,CDKL3,REEP2,KAT8,EFCAB2,ALDH1L1,ADAM28,LILRA2,GRIK5,GRIN1,GSN,ICA1,KHK,MAP4,SCAMP5,MPP2,ZNF862,NTRK2,NUMA1,PLCD1,PRKAB2,BCAS3,ZCWPW1,KLHDC8A,KCNIP1,ZNF821,STUM,SNAP25,TSPYL2,TBCEL,CDK20,WBP2,UGT8,FLRT1,ZNF74,GDPD5" Drug 3399_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AP2A2,APAF1,KCNAB2,MARK4,ATP1A2,ATP2A2,CAMK2B,CHI3L2,CNTN1,AKAP6,SNCAIP,MICAL2,RUSC2,C2CD2L,RABGAP1L,ERCC2,TUBB4A,FHL1,C1orf61,AFF2,GAD1,SIGLEC8,GNG3,GPM6B,GRIK5,NXPH3,HLF,TJAP1,KCNJ3,KCNMA1,KIF5A,MAP2,MX1,MYO7A,NEFM,NELL2,NEUROD2,EPN1,MAPK7,ENOX1,RFX3,NUDT11,KLHDC8A,SYNDIG1,PKNOX2,UNC5B,ZC3H13,NXT2,MAPK8IP3,TAC3,TMOD1,TTPA,VLDLR,PHTF2,SENP7" Drug 4959_UP Apramycin [37321-09-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AMPD3,APBA2,EPB41L5,PPFIA3,ASPH,BTRC,RHBDL1,CBFA2T2,NEURL1,ARHGAP33,FOXN3,CHRNB2,CNTN1,ARHGEF10,PDE4DIP,NOS1AP,RASSF2,DUSP9,SIDT2,EFNB3,ING4,TNK2,FGF1,FYB1,GAD2,STON1,HRH3,KLF12,HLF,TJAP1,IL6ST,INPP5B,KCNF1,KCNH2,KCNN1,MX1,NDUFA5,NEUROD1,NTRK2,PPARA,MASP1,PTX3,FRMPD1,RPH3A,TSNAXIP1,BEX1,SPTB,PLCB1,THRA,DAAM2,R3HDM1,CABIN1,CLIP2,ZNF711,KCNAB1" Drug 3138_UP Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "ADORA1,MTUS1,CDC42BPA,ALDH4A1,CCDC181,ATP6V0A1,RGS11,HAP1,EPS15L1,ZFYVE9,DCT,ST8SIA3,CELSR3,EGFR,SORBS3,ELN,ZNF549,CDHR1,OLFM1,FGFR3,GPR153,GNAO1,PRUNE2,GPR12,RAPGEF1,GUCY1A2,KLF12,TJAP1,KCNJ5,MPP2,NPY,NRCAM,KCNK10,CAMKV,BCAS3,PTPRN2,PEX5,RIPOR1,RGS4,RGS12,TTLL7,MAP6D1,SH3BGR,ST6GAL1,SLC1A3,SLC11A1,CXXC4,TMCC1,ATP10B,SYNE2,EXOC7,TRIM2,DAAM2,SEZ6L,FLRT2" Drug 7011_DN "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.99E-06 4.41E-01 1.52E-04 1.73E-03 55 197 "AP2A2,ALAD,PKP4,APBB2,CDC14B,NCOA1,MTMR9,CFLAR,CDK5R1,CAMK2G,CCNT1,SYNGR3,FOXN3,CREM,NCOR1,CSNK1E,SIPA1L1,CTH,PPP6R2,MFAP3L,KIAA0753,SMG7,PARD6A,SGSM2,RABGAP1L,DNM1,EXTL2,KIAA1109,ERAP1,ZNF276,COPS8,MSL3,RNFT2,PADI2,DHX35,MAP4,TMEM260,TMEM231,ZCWPW1,SEC61A2,SIRT2,ZKSCAN3,CDK5RAP2,ZSWIM8,EMC1,SPTAN1,PBLD,FAM168A,PDLIM2,TBL1X,TCF7L2,WBP2,CADM1,RPRM,MAP3K12" Drug CID000003676 lidocaine Stitch 9.19E-06 4.51E-01 1.55E-04 1.77E-03 47 160 "ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,AK2,APOC2,NUMB,CACNA2D1,CALM1,CCK,ASIC3,DMD,DMPK,EGFR,OGA,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GYG1,TNFAIP8L3,KCNK1,KCNK3,KCNK10,ENPP2,ABCB1,PHKG1,PIK3C2A,PRKCB,PRKCG,PKN2,PRKCZ,RET,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,ZFP90,UBTF,DPYSL5" Drug ctd:C043680 ptaquiloside CTD 9.30E-06 4.56E-01 1.57E-04 1.79E-03 41 133 "ASIC2,ADORA3,PCDH10,DST,CACNB4,CDH8,NRXN1,COL9A1,CNTNAP2,SV2A,EBF1,EDNRA,EGFR,OLIG2,ADGRV1,GBX2,SESN1,GGT5,IGF1,ITGAV,LAMA2,MEIS1,MEIS2,MITF,NCAM1,NRCAM,NTRK2,FAT3,PPARA,PROX1,RET,SOX8,FERMT1,ABLIM3,SOX11,SPP1,SYN2,SYT1,PCDHB7,TIE1,PCDH15" Drug 3559_UP Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.58E-06 4.70E-01 1.62E-04 1.84E-03 53 188 "RALGAPA1,C1QTNF1,APAF1,KCNAB2,RGS20,CFLAR,CACNA1G,CAST,SLIT2,NMT2,QKI,RCHY1,CNTNAP2,FAM169A,GREB1,GPRASP1,KIAA0513,TMCC2,RCAN1,EFNB3,EGFR,ELAVL2,ERCC2,F5,DLC1,KIAA1109,AFF2,GAD1,ERAP1,TMEM8B,SESN1,RND1,GNAS,GPER1,KCNH2,MAP2,MMP16,NF1,OXTR,PDE1C,RPS6KA2,SYBU,FAM214B,LIMCH1,SPTAN1,RGL1,PLCB1,ASTN2,RBFOX2,REEP1,EVI5,SLC17A7,KCNAB1" Drug 3325_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 9.58E-06 4.70E-01 1.62E-04 1.84E-03 53 188 "AK2,PPFIA3,CDC14B,ALDH4A1,ATM,CFLAR,FOXN3,ZFYVE9,CSF1,SDC3,GREB1,TBC1D5,JAKMIP2,RHOBTB1,PARD6A,RABGAP1L,DNM2,E2F5,RASGRP1,SUGP2,EGR3,EPB41L1,STX2,FGFR1,FAM49B,CGREF1,SEPT9,RAB30,CACFD1,MAP4,MIA2,MYO9A,OCRL,SERPINE2,PIK3R1,MBOAT7,PRKAR1B,CEP97,RET,RGS12,GSTCD,TCP11L1,SYBU,SMTN,SIRT2,SMARCA4,ERC1,POGZ,PLCB1,EXOC7,TCF7,RPGRIP1L,TRPC1" Drug CID000062790 ED20 Stitch 9.66E-06 4.73E-01 1.63E-04 1.85E-03 23 58 "AP2A1,BCS1L,SV2A,NTM,FGFR1,AFF2,GALC,GHR,GRIA1,IGF1,ITGAM,LSAMP,MAG,MMP16,NCAM1,NTRK3,OPCML,PAX6,PLP1,PROX1,SLC6A7,SLC8A1,MLC1" Drug 5764_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ACTN1,ARRB2,MYRF,BTRC,FOXN3,ASIC3,B4GALT6,CLCN4,SULT4A1,CHD1L,EDRF1,SIDT2,FAM13A,LPAR6,HSD17B14,EPHA5,VPS26C,EZH1,ST3GAL6,DISC1,GBX2,GLYR1,GIT1,ADAM22,ZNF862,NF1,NOS1,PAK3,SERPINI1,RETREG1,NLE1,CNNM2,PTX3,TMEM231,RAB3IL1,SH3TC2,FAM184A,GAL3ST4,KCTD17,KIRREL1,TMEM156,SH3BP2,SLC2A5,SLCO1A2,MYH15,LIMCH1,ZNF415,ARHGAP26,TIAM1,BEX4,CABIN1,TNS1,TPM2,NSD2" Drug 4321_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "NME5,ANK3,ALDH7A1,SRSF11,CRMP1,CNTNAP2,SMG7,SRGAP3,ATN1,FCF1,PLEKHO1,EPB41L1,CINP,DLL3,GABRA2,HBS1L,KCNMB4,RASSF8,AGFG1,IL6ST,KCNN1,KIF5C,MAP4,MDM4,MMP16,NFIX,NTRK2,NUMA1,CDK14,STRN3,MAPK7,PTN,C1orf54,KCTD17,KIRREL1,FBXO11,LIMS2,CCDC88A,BEX1,MAPK8IP3,TBL1X,EHBP1,TCF4,ARHGEF12,DICER1,TMPO,VIPR2,SF1,SPHK2,ZBTB38,WNK1,PRDM2,EVI5,KCNAB1" Drug 5437_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ACTN2,ADD2,ADRB2,ADGRF5,BEGAIN,BIN1,ST3GAL5,CCKBR,ADGRG1,ARHGAP22,RAB33A,ZFYVE9,SULT4A1,SLC4A7,GREB1,ARHGEF4,RIMS3,PLPPR4,EDN3,ING4,C3orf18,IGSF6,SIGLEC8,GDF9,RUNDC3A,GLYR1,GRB10,NR3C1,SOX21,ADAMTS6,ATXN2L,HMGCR,ICA1,ITPKB,MAOB,MAP4,MYO7A,NOS1,PCDH9,PCSK2,PIK3CD,MYH14,NTNG1,SLC1A7,LIMCH1,SNCA,NMNAT2,PEG10,JMJD6,VAMP1,TRIM2,R3HDM1,VSNL1,WNK1" Drug 5998_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "SEMA6A,AMPH,BIN1,GAS7,ARHGDIG,CACNA1G,BAIAP3,CACNB4,CAMK2A,KIAA1549L,FAM189A2,LY86,CRMP1,HIPK3,MBNL2,EGR3,TENM1,RASGRP2,FHL1,FLNC,PRELID3A,TPPP3,FYB1,FYN,SEPT9,SRCAP,PCDH17,RUNDC3A,NR3C1,HRH3,NCAM1,NTRK2,PALM,CDK14,MTRF1L,PROX1,CRTAC1,RFX2,EMID1,WLS,ATXN1,ZNF821,RASA3,DOCK10,CNKSR2,SLC6A9,MAPK8IP3,TRIM2,GPR161,ZNF34,TRIO,MICAL1,ADAMTS9,TIGD6" Drug 5421_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "AK2,AMPD3,ASPH,N4BP2L1,SYNJ2,MTMR3,CAMK2G,NEURL1,TAOK2,SLC4A7,RIMS3,DTNA,DTNB,EDNRA,PLXNC1,VPS13B,SCML2,DLC1,FECH,KIAA1109,FHL1,AGAP2,FYN,STAG2,NCKAP1,RAB30,GLS,PCLO,KIT,NOS1,PDE3B,PENK,LRP12,PPP5C,VPS13C,PTPRE,RFX2,FERMT1,FBXO11,LIMCH1,SNCA,RBM34,DOK5,ATP10B,ASTN2,TBCEL,DMXL2,PIK3R5,TRIO,KCNK12,WNK1,NT5M,ITM2C,RNF170" Drug 5315_UP Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "SERPINA3,ALCAM,LTBP4,GAS7,APOC1,ATM,SLC4A4,ADAM23,CFLAR,BMP7,FAM189A2,QKI,HOMER3,CNTN1,SMARCAL1,PDE4DIP,GIT2,DSCAM,SIDT2,EGR3,SORBS3,EPB41L1,VPS26C,FGF12,CAMSAP1,PDLIM5,FYN,GRB10,ICA1,KIF5C,MATK,SERPINE2,PPP2R5C,NKAIN1,ROM1,ASIC4,SH3BGR,FUZ,FNDC3A,ZNF365,RPH3A,WDTC1,ZCCHC24,SPTAN1,THSD1,ARC,KAZN,MCF2L,ARHGEF12,ICAM5,CABIN1,SEMA3B,NAV2,RNF170" Drug 367_DN "ICI 182,780; Down 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "GRAMD1B,ADORA3,OGT,CDK13,FUBP1,RAB29,CFAP410,CA12,DLGAP1,LHX2,IFFO1,CHD1L,GREB1,ECE2,RCAN1,E2F5,HIPK3,RASGRP1,EGFR,MBNL2,EGR3,SORBS3,CALCRL,GPHN,FGFR3,IQCG,PDLIM5,NSG1,OGA,ZNF276,GLS,LILRA2,GRM1,MAP4K5,IL6ST,ITIH2,JAK2,KITLG,ADAM22,MYO6,NAP1L1,SDK2,SPATA6,C1orf109,RALGDS,GAL3ST4,AP1AR,SH3GL3,SLC8A1,SNAP25,TBL1X,WASHC4,TMPRSS5,UBE3A" Drug 5965_UP LY294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ADCY6,TRMT9B,CDC14B,ASCL1,SLC2A11,BAIAP3,RCBTB2,TPP1,SULT4A1,NRG2,CSF1,SUSD5,MAGI2,RABGAP1L,DRD1,DTNA,C3orf18,CACNG3,ATP8A1,FHL1,ZNF44,GART,GLS,GNAO1,STON1,PCLO,SPACA9,IRAK3,MAP2,MEF2C,NCAM1,NUMA1,PCSK2,PDE1C,PDE3B,PDE4B,SERPINI1,MAPK7,DCHS2,SAMD9,ZMAT4,SH3GL3,SLC1A7,SNCA,SOX2,ARHGAP26,THSD1,MAPK8IP3,PCDHGB6,AP4E1,DAAM2,TRPC1,VIPR2,PLSCR4" Drug 4208_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ADCY6,MRTFA,BIN1,APAF1,APC,CFLAR,HAP1,MAP7,CBFA2T2,SCARB1,SYNGR3,TPP1,RAB26,HOMER3,COL9A2,AKAP5,CREM,MAML1,SIDT2,ING4,ZNF589,OLFM1,IQCG,PDLIM5,GABRA2,GPR17,GPER1,BACH2,IGFBP1,KIT,GIT1,ADAM22,NTRK2,NTRK3,PCDH9,PLCD1,POU6F1,GON4L,GDPD2,PTHLH,RASA3,ZNF334,SLCO1A2,SMARCD3,TNIK,ZSWIM8,BEX1,ACSBG1,TBCEL,RPGRIP1L,BEX4,ZKSCAN5,PARP6,SLC17A7" Drug 201_UP 15d-PGJ2; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ARID1A,NDRG2,KIAA1324,BEGAIN,ARNTL,SLC4A4,CADM3,CACNA1I,CFAP410,CNTN1,NCOR1,C2CD2L,HS3ST2,DYNC1I1,DRP2,TOM1,EFNB3,DCTN4,CEND1,FECH,BAIAP2,C1orf61,NR3C1,BTN2A1,PADI2,ITIH2,KIF5A,MBP,ADAM22,NAP1L2,NCAM1,PCMT1,PFKFB2,CNNM2,ZSCAN32,RAD51D,RBBP6,ASAP3,CHD9,FNDC3A,ELMO2,WDTC1,LMO3,ANKRD28,SIN3B,TPM3,TSN,UBE3A,ZNF142,ZFAND5,LRP8,SLC17A7,MPPE1,CAMK1G" Drug 4569_UP Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "SLC12A5,C1QTNF3,LTBP4,PPP4R4,BRSK2,LARGE1,CHRNB2,TAOK2,CRY2,VCAN,PDE4DIP,CNTNAP2,PHF14,PLPPR4,SRGAP3,ATN1,DTNA,PLXNC1,NCALD,PTK2B,CORO2B,FLT1,DENND2A,GAD1,ERAP1,TMEM8B,RUNDC3A,RND1,RAB30,GLS,KCND3,KCNJ5,VWA5A,NEFM,PIK3R1,RETREG1,LRRN3,ELOVL2,CEP97,CCDC40,C1orf54,FBXO11,ST6GAL1,KIF13A,RBM34,TSNAXIP1,PCDHA5,AP4E1,TK2,ICAM5,TMOD1,OSBP2,FLRT2,MVB12B" Drug 544_UP radicicol; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "NDRG2,ADORA2A,PLA2G6,EP400,APP,ASPH,CADM3,SYNJ2,SLC25A14,TAOK2,ZFYVE9,TMEM184B,NIPBL,CNTFR,SPOCK2,DTNA,EFNB3,IRAK4,KIAA1109,BAIAP2,IP6K2,ANKFY1,ATP2C1,CELF1,MALT1,CACFD1,NR3C1,MUM1,KLF12,MARK3,MBD1,GIT1,SETD4,MBOAT7,PRKACB,MAPK3,RNASEL,STUM,HSPA4L,ZFP30,SH3GL3,RAB3GAP1,INTS9,ZCCHC24,EMC1,KIF1B,CDK19,STX1A,VAMP1,TCF7L2,SPX,ZKSCAN5,NSD2,LMAN2L" Drug 2283_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ADGRF5,SEMA7A,GAS7,PDE8B,ASPH,ATP2B3,N4BP2L1,CACNA1I,CAMK2B,CD86,CDH8,CLTB,DNAJB5,NCOR2,DAPK1,RUSC2,SPOCK3,FRY,EFS,ZNF589,SIGLEC8,GDF9,RND1,GPER1,GRIN1,GRM7,GRM8,HLF,MATN3,MBP,PFKFB2,PLCB2,CDIP1,PTHLH,PTPRN2,FAT4,GAL3ST4,TCP11L1,RYR1,SLA,SLC2A5,SLCO1A2,KDM4B,SYT5,WSCD1,SLC35G2,TNS1,TUBB1,FLRT2,LAT2,MKRN3,PRDM2,KCNAB1,PAK5" Drug 5107_DN Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "APC,APP,STX16,FUBP1,CACNA1A,SCARB1,CHM,KIAA1549L,TPP1,SLC4A7,HAPLN1,DAPK3,BRINP1,CDON,EDIL3,FCF1,EGFR,IRAK4,CDKL3,ETV1,ZNF589,PDLIM5,GAB1,SRCAP,GPER1,SHISAL1,KCNN1,KPNA5,MAPT,MT1M,NEK1,NFYA,CLDN11,PAK3,CDIP1,STRN3,PPARA,PEX5,RAB3IL1,BEND5,RGS4,ZNF671,SLN,SNCA,WDTC1,TNIK,NXT2,ARHGEF9,TNS1,ZNF24,NT5M,EVI5,SLC17A7,SENP7" Drug 3313_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "LTBP4,AMPD3,SEMA7A,CNTNAP1,APBA2,APC,PPP4R4,ATM,ST3GAL5,ARHGAP33,WHRN,NCOR2,SEC14L5,SPOCK2,CTIF,DBT,RUSC2,CDON,EZH1,FOXG1,AFF2,ALDH1L1,GLS,GNG4,GRM8,SLC2A6,ICA1,KIT,LSS,CD200,NDUFA5,NTRK2,CLDN11,PDE1C,PDE4D,CEP97,KCNIP1,SCN8A,PKNOX2,SLC9A5,TSNAXIP1,CDK19,ABCC8,KIAA1107,TRIM2,TNS2,TRPC1,HIRA,FLRT2,ZNF74,SPHK2,NT5M,EVI5,NUP214" Drug 3804_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "RALGAPA1,ADGRF5,APBB2,SEMA4G,CACNB2,CANX,CBS,ARHGEF2,CACNA2D2,CLCN4,AKAP5,TCEAL2,CSF1,RIMS2,TBC1D5,EXOG,HIPK3,OPTN,SCML2,GCNT2,EML4,ELOVL5,SCIN,ITPKA,MAPT,MITF,MN1,CNOT4,TNPO2,MAPK8,GRAMD1C,PTN,RPS20,ZNF821,FBXO11,ANKRD6,PREX2,ZNF415,TSNAXIP1,LHPP,POGZ,SS18,ELOVL4,ARC,ASTN2,TMPO,VAV2,MICAL1,LAT2,KLC2,XRCC4,ZNF24,REEP1,PHTF2" Drug 2996_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "ADORA3,BCAR3,TRMT9B,ANK3,SYNJ2,CBFA2T2,CLGN,CLOCK,RUBCN,ZFYVE16,BRINP1,DYRK1A,ABI2,PLXNC1,C3orf18,PIPOX,ATP8A1,KLF12,MEF2C,MGAT3,OLR1,ENPP2,SERPINE2,RETREG1,PTCH1,PTN,ZSCAN32,PEX5,RET,ARHGEF10L,FOXRED2,SEC14L1,MRAS,RASA3,FRMPD1,ARHGEF40,ELMO2,ZNF415,WDTC1,TSPYL2,MAPK8IP3,CEP68,SYT5,EXOC7,CAMSAP2,RBFOX2,PLPPR2,LMF1,REEP1,MAP3K12,EVI5,KCNAB1,FAM13C,PHTF2" Drug 3258_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.01E-05 4.94E-01 1.69E-04 1.92E-03 54 193 "MTUS1,AK2,OGT,EPB41L5,FAM131A,ARRB1,MPDZ,CFLAR,CACNA2D2,SOCS6,SLC4A7,FAM169A,GREB1,EDRF1,TOM1,EFNA3,EFNB3,ING4,ERCC2,OGA,ZNF44,TXNL4A,GLS,FERMT2,IL6ST,ITPKB,KIF2A,NPTX1,PIK3R1,CCSER2,RGS12,SLC25A36,WLS,TRA2B,SLC22A4,MAPKBP1,EMC1,KDM4C,DIP2A,PLCB1,MTCL1,TBL1X,KIAA0930,TCF7,TCF7L2,CRTC1,AP4E1,TIAM1,ZMYND8,HIRA,VGF,XRCC4,WNK1,ST7" Drug 2184_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.97E-01 1.70E-04 1.93E-03 51 179 "ABHD6,ADORA3,BIN1,CDC42BPA,EPB41L5,DDO,CDK10,ZSCAN18,N4BP2L1,CACNA1G,LDLRAD4,MAP7,SLIT2,ZFYVE9,CABP1,EDRF1,RIPOR2,KIAA0513,DAPK3,CTIF,CNIH3,MFAP3L,TRAPPC9,FGF12,FGR,FOXG1,GPR153,GABRA2,GLUL,CACFD1,IRAK3,MAP4,CLDN11,PURG,POU6F1,PRKCZ,WDR25,TTLL7,SH3BP2,SMARCD3,SPTB,ZBTB43,NPAS3,ATP10B,SAMSN1,KANK1,BHLHB9,TMOD1,FLRT2,FLRT1,ZBTB16" Drug 2830_UP Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-05 4.97E-01 1.70E-04 1.93E-03 51 179 "NDRG2,NME5,ALK,CDC42BPA,APBB2,ATM,SLC4A4,CFLAR,GYG2,SGCE,ARHGEF1,RCBTB2,ZFYVE9,MFAP3L,SMG7,GNE,HIPK3,EGFR,ACSL4,FGFR1,HPCAL4,CAMKK2,SEPT9,TXNL4A,GLS,GNG4,SLC2A6,ELOVL5,HMGCR,IL11RA,KCNH2,KHK,LSS,MITF,PCDHGC3,TMOD2,MBOAT7,MINDY2,PTHLH,PTPRD,C1orf54,MYH14,RPS6KA2,KCNIP1,ASAP3,WDTC1,SPP1,KDM4C,ZNF423,ELOVL4,TRIM2" Drug CID000004515 NO-711 Stitch 1.05E-05 5.13E-01 1.72E-04 1.95E-03 25 66 "ABAT,BSN,SLC32A1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GRIK1,GRM1,GRM2,GRM5,GRM8,EXOSC10,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SOX10,SLC30A3,SLC17A7,SLC17A6" Drug 4562_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,AP2A2,SEMA6A,MRTFA,APBA2,BRINP2,ADAM23,CFLAR,ST3GAL5,IL33,BTRC,CAMK2B,SCARB1,ARHGAP33,SOCS6,TPP1,HOMER3,CPS1,AATK,ING4,DENND4A,ZNF589,FOXG1,ANKFY1,NSG1,FYB1,GAD1,HBS1L,RND1,GPR19,MAP2,MBD1,PDGFRA,NLE1,PLCD1,GRAMD1C,PRPH,GDPD2,PTPRN2,RGS12,TTLL7,SH3BP2,ASAP3,NTNG1,FNDC3A,TMCC1,TNIK,ZHX3,HECW1,BEX1,ARHGEF9,THRA,SEZ6L,TPM1,TPM2" Drug 6408_DN valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,ADORA1,ADRA1D,APBB2,ALDH4A1,SYNJ1,WASF1,MYRF,CAMK2B,CBFA2T2,CRLF1,SOCS6,STOML1,MICAL2,CSNK1E,PDE4DIP,CNTNAP2,DZIP3,EDRF1,DRD1,DSCAM,CNNM1,EFNA3,PLEKHO1,DENND2A,GLYR1,GPR17,GPR19,KLF12,INPP5B,NF1,PDE3B,PFKFB4,MAPK8,FAM120C,PEX5,RALGDS,RGS12,SLC1A7,SLC12A4,ZNF415,SPTB,TAC3,ATP11A,MCF2L,KIAA0930,TRIM2,CHST8,GPR161,PIK3R5,CDK20,ZMYND8,NT5M,SEMA3B,RNF146" Drug 3754_DN Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,AK2,MRTFA,DOC2A,AMPD3,CDC42BPA,ASPH,SYNJ2,SOCS6,CHM,RAB28,AKAP7,CSNK1E,RIMS3,SGK2,MBNL2,STX2,DCTN2,CGREF1,TRAF3IP2,ZMYND11,GLYR1,GPD2,HSF2,INPP5B,LIFR,MAPT,MX1,NF1,CNOT4,ODF2,CDIP1,LRP12,SAMD9,ARHGEF10L,MCMBP,TCP11L1,RPS6KA2,RXRA,NLGN1,SNCA,PEG10,LHPP,ATP11A,FBXW11,SMG6,TMPO,TNS1,TPD52,HIRA,LAT2,SPHK2,KAT6A,TIGD6,RNF170" Drug 7215_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,ADORA2A,APAF1,APBB2,SEMA4G,RGS11,CHM,TAOK2,CLCN3,STOML1,FAM189A2,IPCEF1,SDC3,RASSF2,GIT2,SLC12A6,ST8SIA3,STX2,FGR,SORBS1,ALDH1L1,GLYR1,GPD2,ADAMTS13,GRIK5,IRAK3,SYNPO,ITPKB,LIG4,MEF2C,CD200,MPP2,ZNF862,NF1,NUMA1,PTPRB,KHDRBS2,RGS12,KCTD17,EMID1,SH3GL3,SYBU,SLC1A7,PREX2,ZEB1,THRA,TMOD1,DAAM2,AMACR,TRPC3,KCNK12,DNALI1,EPM2A,RNF170,SSPN" Drug 3537_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "KIDINS220,AK2,PLA2G6,BEGAIN,BIN1,RASL11B,ATM,BTRC,CFAP410,CA12,QKI,RIMS3,G3BP2,TOM1,ACSL4,ZNF589,BAIAP2,FHL1,FLNC,PRELID3A,GPR153,GAB1,HBS1L,MSL3,HNMT,ADAM22,NEK1,NF1,NUMA1,PALM,PLXNB1,POLG,PRKAR1B,MAPK8,PRODH,RAD52,ZDHHC14,ROM1,EMID1,SEMA6D,SH3BP2,SMTN,KIF13A,RBM34,CEP68,PHLDB1,MCF2L,CHST8,SLC44A1,TMOD1,PARD3,VAV2,SPHK2,MAP3K12,UBE3B" Drug 2483_DN Cefaclor [70356-03-5]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "APBB2,CASK,STX16,BACH1,SYNJ2,CD86,SCARB1,CLCN4,TMEM184B,SLC4A7,CRY2,CSF1R,PPP1R16B,RUBCN,EDRF1,DBT,TRAPPC9,TOM1,HIPK3,EFNA3,ABI2,TUBD1,PTK2B,KAT8,GALC,INPP5K,GLYR1,LILRA2,PADI2,SCAMP5,GIT1,NFYA,SLC11A2,PLCD1,MINDY2,PKN2,CNNM2,PTK2,PTPRN2,CEP97,ZNF821,SH3BP2,FNDC3A,FAM214B,NXT2,CEP68,ADGRL3,KIAA1107,ZEB1,ICAM5,PIK3R5,ZNF24,SYNC,ZNF225,SENP7" Drug 5067_UP Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "APAF1,APOC1,CDK10,PPP4R4,ADGRB1,KSR1,MTMR3,CACNG1,CHN2,CHRNA4,ZFYVE9,HOMER3,CNTFR,ABCG1,ARHGEF10,CYBB,TOX,DMPK,DNAH9,DSCAM,ABCC9,TUBD1,COQ7,MTSS1L,F5,FGFR1,DCTN2,ERAP1,DISC1,MSL3,GPM6B,GRIN1,IGFBP1,ITGA7,ITIH2,LSS,MAPT,AFDN,MSR1,LYRM9,MYO7A,PDPK1,MAPK8,GRAMD1C,PTCH1,RAP1GAP,RGS10,RGS12,KCTD17,S100B,FRMPD1,ARHGEF40,ATP10B,R3HDM1,ZFP37" Drug 7462_UP DO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SLC12A5,MRTFA,BIN1,APOC1,ALDH4A1,KSR1,SCAPER,MTMR3,CCKBR,FOXN3,SOCS6,TBC1D5,SLC12A6,ATN1,EFNB3,MBNL2,SORBS3,MRNIP,ENO2,SEMA4D,RAB30,GLS,GPER1,KLF12,DHX35,MMP16,TAGLN3,LYRM9,MYH6,NTRK3,TREM2,LRP12,WDR25,PTAFR,FAM120C,CCDC25,SH3BP2,WDTC1,ZHX3,UNC5B,ARHGAP26,TSPYL2,VPS13A,TCF7,TF,AP4E1,DAAM2,PIK3R5,TRIO,ZBTB14,STMN4,MPPE1,HRASLS,PHTF2,SSPN" Drug 3196_DN Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADRA1D,ALCAM,MRTFA,TRMT9B,PPFIA3,MARCH3,DNAH17,MARK4,NUMB,ALDH4A1,ATM,ATP2A2,CFAP410,CAMK2G,ARHGEF1,TAOK2,PLAA,ARHGEF6,AKAP7,CRY2,SDC3,CTH,CYBB,DSCAM,DMTN,LRRC23,BAIAP2,CAMSAP1,ZNF44,POLL,LPAR4,IPO5,NNAT,CNOT4,NRGN,PDE3B,WDR25,TMEM231,ZCWPW1,RGS3,RGS12,EMID1,ABLIM3,SLC1A7,KIF13A,WDTC1,SOX3,LHPP,ELOVL4,DOCK9,TMEM121,CHST8,VAV2,ZNF74,EVI5" Drug 6629_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,AP2A2,MRTFA,PPFIA4,APC,DNAH17,ARMC8,COL9A2,AATK,CSNK1E,ARHGEF4,EDRF1,MFAP3L,SGSM2,DMPK,PLEKHO1,LRRC23,C1orf61,SEMA4D,DISC1,CACFD1,GRM8,KCNMA1,KIF2A,MAPT,MBD1,AFDN,NF1,SLC11A2,SETD4,PDE4D,MAPK7,MAPK8,CNNM2,ZCWPW1,KIRREL1,ZC3H14,ASAP3,FUZ,SLC1A7,IQSEC2,DDN,NCDN,MAPK8IP3,KIAA1107,TCF4,TIAM1,OSBP2,LMF1,WIPF1,WNT7A,XRCC4,NDRG4,NT5M,NAV3" Drug 7383_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RALGAPA1,ARID1A,ADCY6,PPFIA4,BTRC,ADGRG1,DNAJB5,PICK1,PDE4DIP,SMG7,EXOG,TRAPPC9,ABCC9,CNNM1,PLEKHO1,ETV1,FGF13,FLT1,FYB1,SIGLEC8,ZNF276,GLYR1,GPR22,GRM1,TJAP1,DIPK1A,ITPKA,KIF5C,MAPT,MX1,NELL2,CLDN11,RIPOR1,TMEM231,SH3TC2,FAT4,GAL3ST4,RGS12,NEK11,FBXW7,FRMPD1,RBM34,EMC1,UNC5B,SPTAN1,ST5,ACSBG1,ASTN2,ATP13A2,TMEM121,BEX4,CABIN1,REEP1,MVB12B,UBE3B" Drug 3398_DN Felbinac [5728-52-9]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "APLP1,FAM131A,ASPH,SCAPER,SLC16A4,CLGN,LY86,ARHGEF6,PICK1,AKAP7,PDE4DIP,NOS1AP,GPRASP1,SPOCK2,CTIF,MFAP3L,EDNRA,EN2,FAM198B,CAMSAP1,FOXG1,AGAP2,IQCG,PDLIM5,PRELID3A,ALDH1L1,SRCAP,RUNDC3A,KIT,NDUFA5,NF1,NOS1,PDE3B,CDK14,PLTP,STRN3,MAPK10,MYH14,SELL,RASA3,PPP1R9A,PEX26,SNCA,KIF13A,ZNF423,ELOVL4,RGL1,STX1A,TBCEL,PIK3R5,TRIO,WIPF1,ZFP37,PRDM2,ITM2C" Drug 2472_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADORA1,PLA2G6,BEGAIN,PKP4,ALDH4A1,ADGRB1,BMP7,BTRC,CFAP410,MAP7,CDC42,CHI3L2,ZFYVE9,AKAP6,SIPA1L1,RIMS2,DAPK3,CNIH3,MFAP3L,ATN1,SGK2,MBNL2,PDLIM5,B3GAT1,CPLX2,GLYR1,GLRB,GPM6B,ATF7,LILRA2,GRM3,IL6ST,ITIH2,KCNJ5,KCNQ3,MBP,MYT1,CDK18,PID1,SYNDIG1,RYR1,SOX2,CAND2,HECW1,ARHGAP26,DDN,SEPT8,PHLDB1,PCDHGA10,ATP13A2,RBFOX2,PRMT8,TRIO,KLC2,GAN" Drug 3931_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADCY2,BBOX1,BIN1,PDXK,MARK4,AZGP1,PICK1,WHRN,MYRIP,SNCAIP,RIMS2,RIMS3,SV2B,SPOCK3,DYNC1I1,ECM2,HIPK3,RASGRP2,KCNMB2,SPEG,CDHR1,REEP2,ZNF589,FOXG1,CSPG5,NSG1,GABRA5,ATP8A2,C1QL1,POLL,PCLO,GRIK4,GRM2,PTGDR2,IGF1,CTNNA3,NPPA,PCBP3,KCNK10,PFKFB2,CAMKV,PRKCB,GDPD2,ELOVL2,SATB1,STUM,CDK19,ATP11A,TBCEL,TMOD1,TRO,UGT8,OSBP2,SLC30A3,PRDM2" Drug 4981_UP Harpagoside [19210-12-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,ABHD6,NDRG2,LTBP4,APBA2,PPFIA3,ARHGDIG,ASPH,MTMR3,CACNA1I,CACNB2,CAMK2G,CBFA2T2,ARHGAP33,TPP1,HOMER3,AKAP7,CRY2,AATK,MICAL2,RIMS2,SPOCK2,DSCAM,SIDT2,ZNF589,FGF13,GPER1,GRM1,GSN,RASSF8,KCNH2,MOBP,MYO9A,NF1,NUMA1,CLDN11,P2RY1,PIK3CD,NLE1,CEP41,PRKAR1B,MAPK7,PTHLH,RPRD1A,NEK11,TCP11L1,FBXO11,RGL1,VAMP1,ARC,WSCD1,ZEB1,TEX15,TRPM2,ZNF711" Drug 7359_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,ABHD6,ALCAM,AMPD3,APBA2,PLA2G4C,NUMB,CFLAR,ST3GAL5,LRRFIP1,PLAA,BAG4,CREM,PDE4DIP,RIMS2,PPP6R2,EDRF1,GIT2,DBT,DTNA,HSD17B14,LRRC23,KIAA1109,FGFR1,TRAF3IP2,MSL3,GRB10,KCNF1,KCNH2,NPR2,PDE4A,SERPINE2,POLG,MINDY2,PRKAR1B,RGS10,NEK11,ATXN2,ZFP30,ZNF365,PPP4R3A,EPN2,COA1,WDTC1,SOX2,DIP2A,WWC1,SZT2,PCDHA6,TMEM121,TRIO,VIPR2,MAP3K12,DNALI1,ZNF248" Drug 4293_DN Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "NDRG3,ADRA1D,GAS7,CDK10,ASPH,ALDH4A1,SYNJ1,BAIAP3,CACNA1A,CBFA2T2,RCBTB2,CHM,HOMER3,CPS1,AK5,DTNA,EGFR,SORBS3,ING4,RGS17,COQ7,FGF1,DISC1,SRCAP,C1QL1,POLL,CACFD1,SOX21,KCNMA1,GIT1,NF1,NFYA,NTRK2,NUCB1,ODF2,OPCML,PAK3,PDPK1,MAPK7,PEX5,RAB3IL1,BEND5,GSTCD,SBF1,ELMO2,BTBD7,SNCA,LHPP,RPGRIP1L,CRTC1,RPRM,VIPR2,XRCC4,PHTF2,SENP7" Drug 3450_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,NDRG3,KIDINS220,OGT,BCAS1,ARHGAP5,MPDZ,BTRC,KYAT1,B4GALT6,BAG4,FAM169A,RUBCN,MFAP3L,SMG7,DLG3,DSCAM,TOM1,TSPAN5,HIPK3,EIF4G2,ZNF589,ATP2C1,B4GALNT1,GLS,GLUL,MAPT,MIA2,ADAM22,NPR2,NRGN,SLC25A23,MAPK8,CEP97,RAP1GAP,RGS10,SEC61A2,MYH14,FBXO11,FNDC3A,ABLIM3,SLC20A2,ZKSCAN3,LIMCH1,SPART,TMPO,TPD52,VAV2,XRCC4,MAP3K12,NAV2,C12orf4,PHTF2,RNF170,AAAS" Drug 3750_DN Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ALK,AMPD3,ARHGEF2,CHM,B4GALT6,TPP1,ABCG2,AKAP7,NCOR1,CSF1,CNTNAP2,SMG7,RCAN1,SGK2,STX2,ERAP1,ARFIP1,GFER,C1QL1,MSL3,CACFD1,RASSF8,IL6ST,JAK2,MAP4,MAPT,MX1,NF1,CNOT4,PAK3,PLCD1,PPARA,PRKAR1B,GRAMD1C,CNNM2,ZSCAN32,FAM120C,RAP1GAP,ENOX1,TTLL7,SCN8A,DZIP1,FAM214B,SNCA,ZHX3,IQSEC2,COLGALT2,PHLDB1,ARC,EXOC7,KIAA1107,PSD3,AHCYL2,VGF,DPF3" Drug 4505_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ARID1A,ADD2,APAF1,CDK13,ATP1A2,AZGP1,BMP7,LDLRAD4,CACNA2D1,CBS,CDH8,CRLF1,TAOK2,LHX2,STOML1,DNAJB5,HOMER3,AKAP6,COL9A3,TCEAL2,NCOR2,ARHGEF10,ARHGEF4,CYBB,MAGI2,SEMA3D,COQ7,LRRC23,EPHB1,FLT1,GAB1,ZNF44,GDF9,GRM1,GSN,LAMA2,SMAD1,MAP2,ADAM22,NOVA2,EPN1,PTPRH,ZSCAN2,CCDC40,ZMAT4,RGS3,HKDC1,SLC6A9,SLC6A11,FAIM2,ZHX3,SEMA4A,ADGRL3,OSBP2,SPHK2" Drug 2640_DN Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,PPFIA3,ARHGDIG,ALDH4A1,RIPK1,ST3GAL5,ARHGEF7,CFAP410,CAMK2B,ZFYVE9,FAM189A2,COL9A2,SLC4A8,BAG4,CREM,NCOR1,ARHGEF4,DAPK3,FBXL5,DSCAM,EFNA3,EPB41L2,F8,FAM49B,GPER1,NR3C1,GRM7,RNFT2,MAN1B1,HNMT,LIG4,NF1,RIPOR1,CEP97,RAD52,ROBO1,SGK1,EPN2,ELMO2,ZBTB43,TSPYL2,CLASP2,NCDN,STX1A,EXOC7,TCF7L2,VAV1,MICAL1,CLDND1,REEP1,EMSY,WIPF2,MVB12B,ACTR3B,SSPN" Drug 3289_UP Biotin [58-85-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,NDRG2,FZD9,KIAA1324,SEMA7A,CNTNAP1,KCNAB2,PRX,PPP4R4,INA,CDH10,FOXN3,CLCN4,WHRN,ABI3BP,ARHGEF10,RIPOR2,CTIF,MFAP3L,DMD,CDON,CACNG2,OGA,POLL,ADAMTS13,GRM3,GPR45,HPCA,ITIH2,KCNN1,KIT,LRP1B,MEF2C,MMP16,ADAM22,NNAT,MAPK8,PLPPR1,PTPRH,FRMPD1,ASAP3,FNDC3A,SLC1A7,SLC9A5,TSNAXIP1,PCDHGA10,PCDHA5,HEY2,TNS1,CHST5,TRO,SPHK2,NT5M,KCNAB1,ADAMTSL3" Drug 3104_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "MTUS1,BCAR3,SEMA4G,ARRB1,DNAH17,CLDN10,NEURL1,TAOK2,NMT2,CREM,SLITRK5,SNPH,CNIH3,MFAP3L,SPOCK3,CNNM1,OLIG2,SPEG,DLC1,FGFR1,ERAP1,RUNDC3A,GNG3,GPM6B,KIF3A,KCNJ5,MAP4,AFDN,CD200,N6AMT1,LYRM9,MYO6,NAP1L2,NCAM1,NTRK2,PURG,POLG,PPP2R2B,PPP5C,CEP41,RFX2,TCP11L1,FOXRED2,ZNF821,GALNT10,LIMS2,SHANK2,SLCO1A2,IQSEC2,TAC3,EXOC7,TBCEL,SZT2,CHST8,XRCC4" Drug 4968_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADORA2A,AP2A2,APOC1,APP,ASPH,NCOA1,ATP6V0A1,CFAP410,TPP1,AKAP7,SLC4A7,CNTNAP2,DCAF8,ACOT8,DTNA,HIPK3,KIAA1109,C1orf61,OGA,GABRA2,SYT17,MALT1,RAB30,POLL,GNG4,GRB10,CACFD1,ELOVL5,IPO5,VWA5A,MATK,KITLG,MSI1,ADAM22,NPR2,PLCD1,MBOAT7,PEX5,RAB3A,ZDHHC14,RNASEL,SH3BP2,PREX2,PEX26,SLC6A8,RBM34,ZCCHC24,LHPP,SS18,ARHGEF9,EXOC7,TCF7L2,PHTF2,NUP214,ZNF248" Drug 7398_UP Merbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADORA1,MTUS1,AMT,APC,GAS7,PDE8B,RAB26,COL9A2,AATK,VCAN,CNIH3,SMG7,RABGAP1L,EXOG,EDN1,HIPK3,IRAK4,ING4,MTSS1L,ANKMY1,TAOK3,DLC1,FGF13,SEMA4D,DENND2A,SIGLEC8,CSDC2,GLI2,SOX21,SHISAL1,IL12A,KCNJ5,NPR2,CLDN11,PDE4D,CDIP1,CNNM2,ZSCAN32,PTPRE,RAB3A,ZDHHC14,KCTD17,ARHGEF10L,FBXW7,SEMA6D,ASAP3,MYH15,KDM4B,TSNAXIP1,CEP68,PHLDB1,KAZN,KLHL4,ZKSCAN5,UBE3B" Drug 5797_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ACTN2,ADD2,NME5,ANK2,ASGR1,CACNA1I,MYRF,BTRC,CDH8,CACNA2D2,RAB33A,PDE4DIP,FAM131B,RABGAP1L,DYRK1A,EDNRA,MBNL2,ELAVL3,LRRC17,DLC1,SEMA4D,PDLIM5,RAB30,GNAO1,SPACA9,HMX1,IL6R,MAPT,MMP17,MX1,NCAM1,NPPA,PDE3B,PFKFB4,MASP1,PTN,STUM,NTNG1,SLN,TNIK,SPP1,SS18,MAPK8IP3,CUX2,TMOD1,DAAM2,LILRA4,ZMYND8,VAV1,ZNF711,TFIP11,NAV2,SLC17A6,EPM2A,NUP214" Drug 5645_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "BIN1,PRX,BRINP2,SLC4A4,KSR1,CACNA1I,CHN2,WHRN,CPS1,NOS1AP,SPOCK2,ATN1,DSCAM,ECM2,SIDT2,EFNB3,TENM1,EZH1,FUT9,SIGLEC8,GRM7,CELF3,KCNK2,KIF5A,VWA5A,MOBP,MYCN,NOVA2,NTRK3,CDK14,PLP1,PTAFR,ZSCAN2,C1orf54,KLHDC8A,PNMA8A,EMID1,ZFP2,SCG5,DOCK10,SLC1A7,SLC2A5,LIMS2,SLC9A5,SLC11A1,TSNAXIP1,PEG10,SEMA4A,EXOC7,ADGRL3,WSCD1,ACSL6,CRB1,CHST5,WIPF1" Drug 2676_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "MTUS1,PLA2G6,PPP4R4,CASK,ARRB1,RGS20,BTRC,USP2,NEURL1,CLGN,B4GALT6,CHRNB2,EPS15L1,QKI,KIAA0513,ZNF337,DGKG,DLG3,ATN1,SGK2,HIPK3,EGFR,TNK2,RASGRP2,CDHR1,ZNF589,FER,CAMSAP1,GATM,HPSE2,SYNPO,MEF2C,MYO7A,PLCD1,PURG,MAPK7,GRAMD1C,RAD52,SUGCT,MYH14,ZNF821,KIF16B,CPEB3,SLC11A1,SLCO1A2,NPAS3,TCF7L2,RPGRIP1L,CHST8,ZNF34,TK2,TRPS1,LMF1,EPM2A,PHTF2" Drug 3023_UP Iodixanol [92339-11-2]; Up 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RALGAPA1,ABAT,ANK2,APC,APOC1,SEMA4G,ASCL1,ASPH,ALDH4A1,MYOM1,NRP2,BMP7,CACNA1I,CACNA1G,KALRN,CDH10,GPR37L1,CHN2,PICK1,TOX,EXOG,ST8SIA3,EDN3,CNNM1,EFS,F5,ZMYND11,ALDH1L1,PCDH17,RUNDC3A,GLI2,GLS,GPR37,SPACA9,HRH3,KCNH1,SMAD1,OMG,CCSER2,PLXNB1,TNPO2,PPARA,PTPRN2,ATG16L1,RGS4,SCN8A,ZNF821,ST8SIA1,PALLD,DDN,TACR1,PHF24,TIAM1,LILRA4,SSBP2" Drug 2657_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASPHD1,ASIC1,ADORA1,MRTFA,DOC2A,TRMT9B,AMPD3,APBB2,CDK13,FGF17,BAIAP3,BTRC,CFAP410,CA4,SCARB1,ARHGAP33,SLIT2,ABI3BP,IFFO1,NRG2,AATK,LRIG1,ARHGEF10,PDE4DIP,GIT2,DNAJC6,MFAP3L,KBTBD11,SCARA3,SIGLEC8,SRCAP,ADAMTS13,GRIN1,KCNJ4,KCNMA1,MOBP,NDUFA5,NOS1,SEPT4,PPARA,CNNM2,ZSCAN2,FAM184A,TCP11L1,SNAP25,KDM4C,SPTAN1,IQSEC2,SYT5,SMG6,PCDHGA10,AP4E1,TPM2,ZBTB38,KCNAB1" Drug 3749_UP Solasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,KLRC4,SEMA6A,SLC4A4,CACNA1A,KALRN,SULT4A1,ERC2,BRINP1,DSCAM,ELAVL3,EPHB1,ETV1,FGF12,FGR,NSG1,B3GAT1,GAP43,GFRA1,ADAMTS13,GRIN1,GRM2,IL1RAPL1,AP4S1,IRAK3,HMX1,IRF8,KCNB1,KCND3,KCNN2,TAGLN3,LYRM9,MYL3,NRCAM,PDGFRA,TNPO2,PTPRB,SEMA6D,ST8SIA1,PREX2,PPP4R3A,KANSL3,RIMS1,MAPK8IP3,VAMP1,MCF2L,TAL1,KLHL4,PCDHGA10,PCDHA6,SLC44A1,TPM2,TRPC3,PDIA2,FLRT2" Drug 2269_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ACTN2,ARID1A,DDO,ARRB2,PDE8B,MARK4,ATP2B2,CADM3,RGS11,FGF17,NRP2,CD86,CBFA2T2,CSF1R,VCAN,CNTNAP2,SDC3,FRMPD4,SPOCK3,HSD17B14,ZNF589,CAMSAP1,C1orf61,RASL10A,NEU3,ALDH1L1,RND1,GLS,GRM2,IRF8,TJAP1,KCNQ3,MGAT3,MOBP,CDK14,SAMD9,PTHLH,CRTAC1,SLA,SLC1A2,PDZD2,SOX10,HECW1,SPART,ATP10B,ABCC8,ARC,EXOC7,ADGRL3,WSCD1,PCDHA5,TGFBR3,PRMT8,PLSCR4,SMIM8" Drug 6363_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "TKTL1,ARID1A,FZD9,ANK2,APBA2,CDC14B,B3GALT2,CFAP410,HAP1,USP2,CDH2,COL9A1,CRYM,EDRF1,SLC12A6,VPS13B,EXTL1,ACSL4,HPCAL4,AGAP2,GAB1,TMEM8B,SIGLEC8,SRCAP,GNG3,GPM6B,GPER1,GRIK1,RASSF8,HLF,IL11RA,KCNA2,MMP17,NOVA2,NPPA,NTRK2,OGG1,PFKFB2,PIK3CD,PROX1,SYNDIG1,SCN2B,ASAP3,DOK5,EMC1,ZC3H13,ARHGAP26,SAMSN1,NXT2,ACSBG1,SYT11,POPDC3,ZEB1,ETNPPL,STMN4" Drug 4765_UP Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,RALGAPA1,ADORA1,SEMA4G,MARK4,ATP2B2,BACH1,ADGRB1,NRP2,SYNJ2,SCAPER,CALB2,KYAT1,CDH2,LARGE1,EPS15L1,RCHY1,RUSC2,SRGAP3,TRAPPC9,ELAVL3,VPS13B,ZNF589,FOXG1,CAMKK2,FYN,TMEM8B,ATP8A2,STMN2,CACFD1,GRM7,HLF,KCNMA1,MAOB,AFF1,ADAM22,OPCML,KCNK10,PFKFB2,PLXNB1,NECAB2,POU6F1,SNRK,TCP11L1,EMID1,KDM4B,HECW1,UNC5B,CDK19,SYT11,SYT5,TK2,TPM2,SLC17A7,SENP7" Drug 3531_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ACTN2,MRTFA,APBA2,APBB2,APLP1,DDO,FAM131A,AQP4,ADAM23,CACNB2,TAOK2,CREM,PDE4DIP,EDRF1,NOS1AP,ARHGAP24,TMCC2,DTNA,SGK2,FRY,ELAVL2,RRAGB,DLC1,ZNF589,FGFR1,B3GAT1,SEPT9,RUNDC3A,GLYR1,GPM6B,GSN,TJAP1,KCNMA1,LAMA2,MATN3,MSI1,ADAM22,NCAM1,NF1,NTRK3,CDK18,PACSIN1,PPP5C,ELOVL2,RAB3IL1,GAL3ST4,RGS12,TCP11L1,ST6GAL1,KAZN,SMG6,TNS1,ZIC3,KCNAB1,MVB12B" Drug 3632_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SYN3,ASIC1,PPFIA3,ARRB1,CACNA1D,CACNA2D1,CALB2,CAMK2B,INA,ABI3BP,CSF1,IPCEF1,CTIF,RUSC2,CDON,DRD1,DTNB,EDN1,SGK2,EFNB3,ELAVL3,ANKMY1,DLC1,KIAA1109,GPM6A,INPP5B,KIF5A,ADAM22,NF1,NPR2,PFKFB2,PLXNB1,TNPO2,PTAFR,RAD52,KHDRBS2,RAVER2,STUM,RASA3,SH3BP2,SH3GL3,SLC11A1,SHANK2,SNCA,WSCD1,PCDHGA10,GPR161,TNS1,CHST5,TRIO,TRPC1,UGT8,SPHK2,SLC30A3,KCNAB1" Drug 3092_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,BRAP,AGT,FAM135A,APBB2,APOC1,PPP4R4,MTMR3,HIP1R,SCARB1,JAM2,CLCN4,CREM,SIPA1L1,RIMS3,EXOG,HIPK3,RBM12,TNK2,TUBD1,ERCC2,PTK2B,OLFM1,EFCAB2,GAB1,GABRA4,ADAM28,LILRA2,GRM1,KIFC3,LAMA2,LSS,SMAD1,MAP4,MEF2C,POLG,PTPA,PTCH1,TCP11L1,SEC14L1,PPM1E,SLC20A2,SNCA,TMCC1,KDM4B,TNIK,KIF1B,KAZN,TGFBR3,ZNF34,TMOD1,R3HDM1,TPM3,ZNF32,PRDM10" Drug 4800_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AP2A2,LTBP4,AMPD2,BIN1,ANK3,PPFIA3,MARK4,CFLAR,HAP1,KYAT1,ARHGAP33,SLIT2,SH2B1,CSNK1E,SDC3,HP1BP3,ATN1,DSCAM,SEZ6L2,TSPAN5,EFNB3,PLXNC1,FGFR1,BAIAP2,CACFD1,ELOVL5,MAP4,MITF,PIK3CD,PLEC,PLXNB1,PACSIN1,FA2H,GON4L,WDR25,PTPRE,FAM120C,RIPOR1,RAB3A,RAD52,KCTD17,ANKRD6,KIF13A,TROVE2,CEP68,TTBK2,TACC1,KIAA0930,TCF7L2,TK2,CDK20,CADM1,REEP1,MAP3K12,SSPN" Drug 4286_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SYN3,ALK,AMPD3,PKP4,APOC1,ZSCAN18,SLC2A11,N4BP2L1,ADAM23,RUNX1T1,CBS,LDB2,CCKBR,SLC16A4,CD86,CNR1,AKAP5,CSF1,CSNK1E,VCAN,RIMS2,SHANK1,FCF1,EFNB3,STX2,ZNF549,ETV1,FABP7,ST3GAL6,ZNF44,HPGDS,GPR17,GPR22,GRM2,KCNF1,KCNQ3,MMP16,MOBP,ADAM22,MSR1,MYO7A,MYT1,NNAT,CDK18,PIK3R1,PPARA,ZFP2,FRMPD1,BCAN,RPH3A,ZC3H13,NFASC,MLC1,VAMP1,OSBP2" Drug 3550_UP Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AP2A2,AMT,AQP4,CADM3,ADGRB1,GYG2,CFAP410,NEURL1,CHRNA4,HOMER3,CPS1,PDE4DIP,CNTNAP2,FAM169A,CTIF,SEMA3D,EFNA3,AASS,EN2,LRRC23,RASGRP2,SPEG,DLC1,KIAA1109,TBR1,ZNF44,ERAP1,SIGLEC8,GNAO1,GPD2,GRIN1,GRM8,HPSE2,INPP5B,P2RY1,ENPP2,NLE1,SAMD9,PTAFR,PTN,CCDC40,RPS6KA2,EMID1,ASAP3,CNKSR2,PKNOX2,SNCA,TSNAXIP1,SYN2,WSCD1,SZT2,ICAM5,SEZ6L,OSBP2,AP3B2" Drug 4241_UP Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "C1QTNF3,SEMA7A,PKP4,APC,PPP4R4,ATP6V0A1,HAP1,CBS,LDB2,KRIT1,B4GALT6,CSF1,CNTNAP2,PHF14,MAML1,DAPK3,MFAP3L,MAGI2,ATN1,ECM2,COQ7,EPHA5,NCALD,CEND1,FABP7,FGF1,CAMSAP1,ERGIC3,IQGAP2,NEU3,GPM6B,RAPGEF4,FAM107A,KCND3,MAN2A2,MDM4,PDE4D,RETREG1,MAPK10,CNNM2,PTN,GAL3ST4,RGS4,RGS12,NTNG1,FBXO11,TNIK,AP4E1,ZNF34,TRPC1,HIRA,LAT2,EMSY,KCNAB1,DPF3" Drug 7303_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "MTUS1,NME5,BIN1,PPFIA3,FUBP1,C5,RCBTB2,AKAP7,FAM131B,ARHGAP32,SNPH,GIT2,DBT,MED24,SGSM2,TMCC2,DLG3,DYNC1I1,CDON,MAMLD1,BAIAP2,FYN,ZMYND11,TXNL4A,CNTRL,MN1,GIT1,NUMA1,PCDH9,RC3H2,SH3TC2,MCMBP,RPS6KA2,ITSN1,KIF16B,BTBD7,SLC22A4,PDZD2,CLASP2,CAMTA2,ST5,PHLDB1,SUPT5H,VAMP1,VPS13A,TCF4,WDR7,ZNF34,TNS1,HIRA,MICAL1,WNT7A,MAP3K12,NAV3,MPPE1" Drug 2345_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RBM10,PLA2G6,PKP4,CFLAR,SYNJ2,HIP1R,USP2,ZFYVE9,VAX2,PICK1,CNTN1,SH2B1,AATK,CTNND1,ZNF337,DAPK1,DAPK3,KIAA0753,SMG7,SPOCK3,DTNA,C1orf61,GPR153,GFER,POLL,KCNMB4,LILRA2,GRIK2,GRIK5,INPP5B,MAP4,NF1,NINJ2,CNOT4,NUMA1,SSH1,NLE1,SLC25A23,PTPA,PTAFR,PLPPR3,TMEM156,SH3BP2,SMARCC2,KDM4C,KIF1B,CLSTN2,ZC4H2,TCF7L2,SZT2,KAT6B,PIK3R5,WNK1,EMSY,KCNAB1" Drug 3223_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ARID1A,NDRG2,GAS7,PRX,CDK13,ASPH,ALDH4A1,CFLAR,SYNJ1,CACNG1,CBFA2T2,CDH2,NMT2,CPS1,NCOR2,CNTNAP2,ARHGEF4,SPOCK2,MFAP3L,EFNA3,FAM198B,ZNF589,FGF12,CAMSAP1,FHL1,PRELID3A,LYVE1,RUNDC3A,GNG3,GRM1,ATXN2L,ICA1,KCNJ4,KCNJ5,MAOB,MATN3,ADAM22,OPRL1,GPR85,PIK3CD,PLXNB1,PPP5C,ZSCAN2,TCP11L1,SLITRK3,SLC14A1,MAPK8IP3,AJAP1,ACSBG1,TMOD1,R3HDM1,TRPM2,FAM155A,FLRT2,KCNK12" Drug 3281_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ALCAM,SRPX,ALK,AMT,APLP1,APP,ARRB1,ALDH4A1,CACNA1D,CAMK2G,PLEKHB1,RAB28,CSF1R,LRIG1,FAM169A,SDC3,TBC1D5,RABGAP1L,FCF1,EPB41L2,ERCC2,ZNF589,C1orf61,TPK1,ARFIP1,GLS,GPD2,TJAP1,JAK2,KIF2A,MSI1,NEK1,NF1,SLC11A2,PRKAR1B,MAPK8,ATG16L1,RGS12,RASA3,PPP1R9A,FERMT1,ANKRD6,SLC1A7,PREX2,ZKSCAN3,WDTC1,ZCCHC24,ELOVL4,VPS13A,PLCB1,CRTC1,AHCYL2,SLC44A1,CDK20,TRIO" Drug 7317_UP Quinic acid [86-68-0]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "PLA2G6,KCNAB2,APC,ALDH7A1,ADGRB2,NRP2,CFLAR,SYNJ2,BAIAP3,BTRC,MAP7,CHM,CHRNA4,NMT2,AKAP5,HAPLN1,MFAP3L,RUSC2,DRP2,EFEMP1,KIAA1109,POMT1,PDLIM5,GABRA2,GAD1,GRM8,KLF12,HNMT,IFI16,KCNF1,MMP16,LYRM9,NDP,PDE4D,PEX5,RGS10,TTLL7,AMBRA1,SNCA,SPTAN1,DDN,TROVE2,MAPK8IP3,ELOVL4,TCF4,SYNE1,SPX,TIAM1,TK2,CABIN1,TPM2,OSBP2,WIPF1,XRCC4,MPPE1" Drug 3756_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADRA1D,AMPD3,CDC14B,MTMR9,BMP7,SYNJ1,CBFA2T2,TAOK2,RAB28,ENTPD4,PDE4DIP,SLITRK5,EDRF1,HP1BP3,DLG3,ATN1,DTNA,SIDT2,SUGP2,ATP8A1,DCTN2,SEPT9,GFER,POLL,PRRC2B,INPP5B,ITPKA,JAK2,MT1M,NF1,ODF2,MAPK7,WDR25,RAD52,SUSD4,ZNF671,MCMBP,ATXN7,SUPT20H,SH3BP2,FNDC3A,DZIP1,DHX30,ELMO2,OGDHL,IFT122,SNCA,ATP10B,SYT1,ATP11A,TIAM1,LAT2,VPS35L,KAT6A,TIGD6" Drug 6206_UP Ricinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SEMA6A,AMH,CDC42BPA,APBA2,APOC1,PPFIA3,CDK10,NCOA1,SLC4A4,CADM3,CDK5R1,BRSK2,NEURL1,SRSF11,LHX2,AKAP6,CSNK1E,CTIF,DRD1,EFNB3,SORBS3,NCALD,GABRA2,USP19,NR3C1,GRM1,BTN2A1,TJAP1,MBD1,TM6SF1,MPP2,OPCML,PDE1C,PLEC,MAPK8,CNNM2,GON4L,PTN,RALGDS,ZNF493,MYH14,RPS6KA2,PPP4R3A,SMTN,BTBD7,SORCS3,IZUMO4,KIF1B,PHLDB1,SYN2,TACR1,ZKSCAN5,PRDM2,SEMA3B,SSPN" Drug 6097_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "LTBP4,BIN1,APLP1,APOC1,ARHGDIG,BCL2L2,CDO1,CLCN4,FADS2,IFFO1,VCAN,DGKB,HEPH,MYEF2,HS3ST2,CDON,ATN1,TENM1,ELAVL2,ELN,CACNG2,TUBB4A,CAMSAP1,EFCAB2,FUT9,FYN,GAD2,GATM,GCK,ALDH1L1,PRUNE2,GPM6B,GRM1,GSN,KLF12,HLF,MGAT3,KITLG,TAGLN3,CNOT4,SNTG1,PPP1R1A,PPP5C,MAPK8,PTX3,C1orf54,SCN2B,SLC11A1,SLN,PEG10,HEY2,MICAL1,CLIP2,KCNAB1,MVB12B" Drug 2768_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,NDRG2,ADORA1,KCNAB2,APOC1,PDE8B,MARK4,ALDH4A1,SLC4A4,SYNJ2,CACNA1I,BAIAP3,ARHGAP33,CHI3L2,CHRNB2,ZFYVE9,HOMER3,CSNK1E,SDC3,ARHGEF4,EDNRA,ING4,ELAVL3,KHDRBS3,GFER,LILRA2,GRIK5,PTGDR2,KCNJ5,MAP4,MATK,PPP5C,PRKAR1B,RELN,PSMD13,ZDHHC14,TMEM206,RTN1,ASAP3,PKNOX2,ARHGEF40,KIF13A,HECW1,IQSEC2,NPAS3,EXOC7,TPM3,TRIO,HIRA,FAM155A,LMF1,ZFP37,PRDM2,KAT6A,NUP214" Drug 5478_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "PLA2G6,BIN1,PPP4R4,PDE8B,CFLAR,RUNX1T1,CD86,PLAA,ARHGEF6,SPOCK2,LYPD1,RABGAP1L,SGK2,PLXNC1,FGFR1,PRELID3A,GAB1,ZNF44,GABRA5,IQGAP2,GFER,GLS,GNAO1,GRIK5,NR3C1,NXPH3,LIG4,VWA5A,LSS,AFDN,MSR1,CNOT4,NOVA2,NPPA,SNTG1,PLCD1,LRP12,PPARA,RELN,RGS4,GSTCD,RPS6KA2,PKNOX2,LIMCH1,ZHX3,PEG10,ARC,SYN2,SEMA4A,EXOC7,CRTC1,TUBB1,NSD2,MAP3K12,EVI5" Drug 5425_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "BIN1,PPP4R4,PLA2G4C,CADM3,HAP1,CAMK2G,CD38,MYRIP,ARHGEF4,SEC14L5,CTIF,SMG7,NTM,DMPK,SHANK1,ATN1,HIPK3,SEMA3D,RCAN2,MTSS1L,HPCAL4,FOXG1,GPR153,FUT9,SIGLEC8,ATP8A2,SRCAP,LPAR4,SPACA9,TJAP1,KCNB1,KCNMA1,KCNQ3,MAP4,MMP17,ADAM22,SNTG1,PCSK2,PDE4A,MAPK7,C1orf54,FBXW7,EMID1,ST8SIA1,SLC9A5,SLC11A1,LIMCH1,SPTAN1,ATP10B,ACSBG1,POPDC3,TMOD1,AMOT,KCNAB1,PLSCR4" Drug 6478_DN Dioxybenzone [131-53-3]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AP2A2,AK2,SEMA6A,BIN1,CDC42BPA,BCAS1,APP,MARK4,STX16,AKAP7,ABI3BP,BAG4,PDE4DIP,CNTNAP2,GIT2,CELSR3,EGFR,SORBS3,DMTN,NCALD,SEMA4D,PRELID3A,MSL3,KCNJ3,IPO5,MATK,NF1,NUMA1,PDE3B,PDE4B,SSH1,PPP5C,PRPH,PTN,ZSCAN32,RGS10,SAFB,BCAN,SMTN,SLC6A8,SPART,TROVE2,NXT2,VAMP1,ATP11A,TACC1,CRTC1,CHST8,BEX4,VGF,VLDLR,CLDND1,XRCC4,EVI5,ST7" Drug 6263_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADCY6,PLA2G6,AMT,APP,CDC14B,SLC4A4,BCL7A,CFLAR,ARHGEF1,NEURL1,ARHGAP33,CHRNB2,BAG4,VCAN,SDC3,RIMS2,INTS1,FBXL5,DSCAM,RCAN1,CNNM1,EFNA3,EPB41L1,DLC1,KIAA1109,OLFM1,FGFR3,PRKAG2,DPYSL4,OGA,SRCAP,GPM6A,GPR19,RNFT2,ICA1,KCNF1,KCNJ3,KCNK1,NPTX1,NUMA1,PPP5C,SIDT1,BSDC1,RGS10,RNASEL,SEMA6D,SYBU,KDM4C,SPTAN1,MAPK8IP3,ASTN2,SEMA4A,ZNF34,VIPR2,NUP214" Drug 5738_DN "Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AP2A2,CDC14B,PPP4R4,BTRC,CA8,SOCS6,ASIC3,B4GALT6,NMT2,TCEAL2,PDE4DIP,SDC3,EDRF1,HDAC4,RHOBTB1,CDON,TENM1,FER,CGREF1,OGA,ZNF276,GNG4,TDRKH,GPER1,GPR37,DHX35,IL12A,KCNH2,MAPT,GIT1,MX1,ZNF862,CLDN11,POLG,PRKAR1B,PEX5,TMEM231,ASAP3,AMBRA1,SLC1A7,PEX26,SLC14A1,SMARCD3,SNCA,TNIK,MAPK8IP3,CEP68,EXOC7,DNAH7,GPR161,HIRA,VGF,NDRG4,EMSY,TIGD6" Drug 2380_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,ALK,DOC2A,AMT,STX16,N4BP2L1,CAPN3,CAST,CD86,FOXN3,ARHGEF10,TRAPPC9,DTNA,E2F5,FEM1B,FCF1,SIDT2,ANKMY1,F5,FCGRT,CAP2,ANKFY1,TRAF3IP2,SEPT9,ALDH1L1,ZNF276,GLYR1,LILRA2,INPP5B,ITGAM,IPO5,LIG4,MEF2C,ZNF862,OGG1,PDE4A,PFKFB2,RGS10,MYH14,STUM,SH3BP2,FNDC3A,SNCA,WDTC1,ARHGAP26,DBNDD2,DDN,FCHO1,ATP11A,KAZN,CAMSAP2,ZKSCAN5,UBTF,PRDM2,ST7" Drug 4019_UP Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASPHD1,ALK,AMH,BIN1,SEMA7A,ARSE,SLC4A4,ADAM23,BMP7,CAMK2B,LDB2,CCKBR,SCARB1,AKAP7,IQCK,AKAP5,CSF1R,CNTNAP2,TOM1,ABCC9,SEMA3D,PLXNC1,ZNF391,DLC1,B3GAT1,GAB1,GAD2,SIGLEC8,GPD1,GPR19,GPER1,GRIK5,MAN2A2,MIA2,MMP16,SLC11A2,PALM,PENK,PHKG1,PLCD1,SPATA6,PKN2,FAM120C,GAL3ST4,SCN2A,DZIP1,PPP4R3A,ELMO2,NPAS3,PHLDB1,KLHL4,CRTC1,CDK20,ZNF24,PHTF2" Drug 1595_UP "Zidovudine, AZT [30516-87-1]; Up 200; 15uM; HL60; HG-U133A" Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,ALAD,PPFIA1,ATM,BACH1,BMP7,CA12,CD86,NEURL1,AP4M1,RCBTB2,CHRM4,CNTFR,AKAP7,PCYT1B,SH2B1,PPP1R16B,DPH1,RCAN1,SIDT2,SORBS3,DCTN4,RASGRP2,F3,OLFM1,CINP,ATP2C1,GJB1,NUDT21,DIDO1,KCNN1,GIT1,NPPA,PDE3B,PLCD1,CDIP1,STRN3,LRP12,MAPK10,CNNM2,PTN,ARID4A,RDX,RNASEL,ATXN7,BCAN,MAPKBP1,ARHGAP26,LARP4,SIRT1,TSN,VIPR2,ZNF142,REEP1,EVI5" Drug 3424_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "FZD9,SRPX,BIN1,PDE8B,ASPH,SLC4A4,N4BP2L1,ADAM15,CFLAR,ARHGEF7,CA4,HAP1,SOCS6,RAB28,ABI3BP,CSF1,FAM169A,RIMS2,EXOG,RCAN1,HSD17B14,EZH1,FAM198B,KIAA1109,FHL1,IQCG,HBS1L,GART,ALDH1L1,INPP1,ITPKB,KCND1,MBD1,KITLG,NPR2,PDE3B,PPP2R2B,FAM120C,RAB3A,RAB3IL1,RYR1,ASAP3,LIMS2,BTBD7,ZKSCAN3,COA1,KIF21B,CAMTA2,THSD1,PLCB1,KAZN,DICER1,TK2,TMOD1,TIGD6" Drug 7514_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABHD6,BIN1,APC,BCAS1,CDK10,SEMA4G,ARHGAP5,ARNTL,ST3GAL5,MTMR2,KYAT1,NIPBL,PREPL,FEZ1,DZIP3,DBT,RUSC2,DSCAM,EGFR,RGS17,STX2,ERCC2,HBS1L,GPER1,GRB10,ACOT7,ITPKB,JAK2,KCNJ3,NF1,CCSER2,RETREG1,PLCD1,SLC25A23,PKN2,VPS13C,RAB3A,RGS12,SEC61A2,PAQR6,ZFP30,FNBP1,KDM4C,SS18,NSFL1C,MTCL1,TCF7L2,PSD3,SIK3,TK2,TPD52,TRIO,CLDND1,XRCC4,ZBTB14" Drug 7549_UP CP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC2,ASIC1,LTBP4,PPP4R4,PDE8B,ALDH7A1,ADGRB2,CRLF1,CHRM4,TAOK2,RAB26,CRY2,PLCH2,RUBCN,RIMS3,DAPK3,DPH1,DSCAM,SEMA4D,SRCAP,GPR19,GRK4,CACFD1,FICD,TJAP1,SCIN,ITPKA,LIFR,ADAM22,TNPO2,PRPH,SAMD9,WDR25,PTN,PTPRN2,ZCWPW1,ENOX1,SUGCT,EMID1,ASAP3,BCAN,CCDC92,SLN,MYH15,IZUMO4,ARHGAP26,POGZ,SYT11,ASTN2,DOCK9,TNS1,PLPPR2,VAV2,STMN4,PCBP4" Drug 5877_UP Azaperone [1649-18-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AGT,CADM3,ADAM23,GYG2,MYRF,CACNA1A,CBFA2T2,CDH10,QKI,CSF1R,FAM131B,GPRASP1,MFAP3L,RABGAP1L,SLC12A6,TENM1,EPHA5,VPS26C,DLC1,FCGRT,FER,GNAS,PRRC2B,GRM8,ICA1,SCIN,KHK,PACRG,MAPT,MATN3,MMP16,MX1,NTRK2,DDR2,SERPINI1,MAPK8,PRPH,RIPOR1,RAD52,ARHGEF10L,PRR5L,TCP11L1,RPS6KA2,PPP4R3A,ELMO2,SLCO1A2,SMARCD3,FAIM2,SSTR2,TK2,CABIN1,TRPC1,OSBP2,NT5M,KCNAB1" Drug 4103_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ACTN2,ALK,CDC42BPA,APC,GAS7,ASPH,CACNA1I,CACNA1G,ARHGEF2,WHRN,SNCAIP,CSF1,VCAN,DZIP3,ARMCX2,MYEF2,ECM2,EFNB3,EGR3,EPHB1,PTK2B,OLFM1,GCNT2,HPGDS,CNTRL,GUCY1A1,ICA1,VWA5A,MAOB,MARK1,GIT1,MX1,MYT1,NOVA2,LRP12,MAPK7,SNRK,RGS10,SYNDIG1,SH3BP2,FRMPD1,PKNOX2,LIMCH1,SNCA,ACSBG1,JMJD6,PHF24,TMOD1,TRPC1,LAT2,ZIC3,SPHK2,SLC17A7,KCNAB1,NUP214" Drug 3876_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "NME5,SPARCL1,ALCAM,BEGAIN,APAF1,SPTBN4,ARHGDIG,MARK4,CFLAR,KSR1,CHN2,ZFYVE9,TPP1,RCHY1,AATK,ARHGEF10,SEC14L5,RUSC2,FAM13A,AASS,ELN,GAD2,LYVE1,GLYR1,RASSF8,KLF12,KCNJ4,KCNK2,KCNN1,MAPT,MID1,MN1,MOBP,NUMA1,PCDH9,STRN3,MINDY2,PTAFR,PTPRN,RNASE1,PNMA8A,ARHGEF40,KDM4B,ZC3H13,TROVE2,INKA2,ARC,DOCK9,AHCYL2,CHST8,PIK3R5,TPM3,TRPM2,XRCC4,PRDM2" Drug 6073_DN 6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASPHD1,AP2A2,AK2,C1QTNF3,PPFIA3,MARK4,ASPH,ATP6V0A1,MTMR3,GYG2,CA12,HOMER3,PDE4DIP,ARHGEF4,RIMS2,MFAP3L,TMCC2,SUGP2,ING4,C3orf18,FAM198B,KIAA1109,FGFR1,GNAS,GNG4,FERMT2,KPNA5,MIA2,MPP2,MSI1,ADAM22,NPR2,PCDH9,PDE4B,PRKAR1B,PRPH,GON4L,ELOVL2,NKAIN1,RGS3,FOXRED2,MAPKBP1,ZHX3,THSD1,PHLDB1,SYN2,KAZN,SLC44A1,TK2,PARD3,TRPC1,UBE2H,MAP3K12,EPM2A,PHTF2" Drug 2556_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "C1QTNF1,AMH,BIN1,ANK2,APOC1,ASPH,CCDC181,KSR1,BMP7,MYRF,MAP7,CDH2,ASIC3,NRXN2,CRMP1,MAGI2,EXTL1,CEND1,F5,PTK2B,FGF12,NBEA,CAMKK2,GAP43,ADAM28,ZNF276,RAPGEF1,PADI2,TJAP1,KCNN1,CD200,MSR1,TAGLN3,NF1,NRCAM,PHKG1,PLCD1,PMP2,FSD1,MAPK10,CNNM2,ZFHX4,RASA3,SYBU,SLC1A3,SLC20A2,DOP1A,SOX2,IZUMO4,TACR1,KIAA1107,ICAM5,PARD3,TRPS1,ZBTB38" Drug 4956_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASPHD1,NDRG2,ADORA1,C1QTNF1,FAM131A,MARK4,ALDH7A1,CFAP410,KALRN,RUNX1T1,CLTB,CNTFR,TCEAL2,CRY2,CSF1,DAPK3,GSDME,EDNRB,OLIG2,KIAA1109,CAMSAP1,FOXF2,ZNF44,GAD1,GAD2,GNAO1,GPM6B,PCLO,GRM1,KCND3,VWA5A,MX1,MYT1,NOVA2,OMG,PIK3CD,ELOVL2,KLHL11,TCP11L1,SLC2A5,PKNOX2,SLC9A5,SHANK2,SNCA,ARHGAP26,RGL1,AJAP1,WSCD1,CRTC1,CABIN1,TNS1,PRMT8,VIPR2,KCNAB1,JPH3" Drug 5852_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RALGAPA1,ACTN2,SPARCL1,ALK,ARRB2,RUNX1T1,KYAT1,CDC42,CDH10,CHRNB2,NMT2,CLTB,QKI,CSF1,VCAN,PDE4DIP,CNTNAP2,PPP6R2,MFAP3L,RUSC2,EFNB3,TNK2,LRRC23,EPHB1,FGFR1,FOXG1,NSG1,GRIK5,KIF5C,LIFR,MIA2,NELL2,NPPA,NTRK3,GPR85,PLCD1,MAPK7,SAMD9,RAD52,RAVER2,NEK11,ASAP3,BCAN,ZNF334,KDM4C,CEP68,MCF2L,ADGRL3,KIAA1107,SLC44A1,RIMBP2,ZKSCAN5,VAV2,WIPF1,KCNAB1" Drug 6797_UP Aconitine [302-27-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "MRTFA,AMT,KCNAB2,CA4,CACNA1D,NEURL1,CDH2,FADS2,AKAP6,PDE4DIP,JAKMIP2,ELMO1,HEYL,EFNA3,MRNIP,HSD17B14,VPS13B,DMTN,FHL1,PDLIM5,GFER,GNAL,GNAS,TDRKH,NXPH3,ICA1,KCNJ5,LAMA2,NF1,NUMA1,EPN1,MINDY2,LRRN3,MAPK7,MASP1,ZNF493,MYH14,ASIC4,ASAP3,RPH3A,SLC1A7,SLC11A1,BTBD7,WDTC1,ZC3H13,TROVE2,EXOC7,PCDHGA10,PCDHGA1,TK2,RUNDC3B,FAM155A,LMF1,ZNF24,KCNAB1" Drug 4964_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "APBA2,CDK13,DNAH17,MARK4,FGF17,GYG2,BAIAP3,LDLRAD4,CAMK2B,RGN,CDH8,CHRNA4,NRXN3,CSF1,MICAL2,OSBPL3,RIMS2,EIF4G2,LRRC23,EXTL1,F5,ZNF589,FGFR1,KHDRBS3,GABRB3,GAD2,ALDH1L1,RUNDC3A,LPAR4,SPACA9,WIF1,C2orf72,KCNH2,MOBP,ADAM22,FXYD7,NOS1,RETREG1,SPATA6,MAPK10,PTHLH,ZFHX4,CARF,RYR1,ASAP3,SLC1A7,FAM214B,TROVE2,WSCD1,CRTC1,PCDHA5,TMOD1,LAT2,KCNK12,SLC17A7" Drug 2447_DN Ceforanide [60925-61-3]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADRA1D,APBB2,ARNTL,HIP1R,MAP7,CDC42,ARHGAP33,EPS15L1,NMT2,COL9A2,CREM,DOCK4,DGKG,DTNA,FEM1B,SIDT2,EFNB3,LPAR6,RASGRP2,CAMSAP1,GATM,ALDH1L1,AHDC1,MSL3,SPACA9,NCKAP1L,VWA5A,MITF,MYO7A,NF1,NINJ2,NPR2,OGG1,PPP3CC,CNNM2,RAB3IL1,RAD52,RNASEL,MRAS,SIRT2,SMARCD3,MYH15,SNCA,TMCC1,IZUMO4,SPTAN1,ARHGEF9,TCF7L2,AHCYL2,TPD52,TPM2,PLPPR2,BEST1,SPHK2,PHTF2" Drug 2372_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ABAT,ADORA1,FAM135A,ANK3,CDK10,NCOA1,B3GALT2,CA12,CBFA2T2,CDH2,SOCS6,NMT2,HOMER3,CREM,DCAF4,INTS1,GSDME,EFNA3,MBNL2,PIPOX,CAMSAP1,PDLIM5,GLI2,GNG4,GRIN1,KLF12,KCNMA1,KIT,MBP,MEF2C,LYRM9,NEUROD1,SLC11A2,NUMA1,PLCD1,SLC25A23,MASP1,KLK6,PTPRB,RGS3,ZNF821,ASAP3,SLC20A2,KDM4B,DOP1A,SPART,TROVE2,TBCEL,TCF7L2,OBSL1,CRTC1,TUBB1,PLPPR2,ZBTB38,EVI5" Drug 3622_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADORA1,ADRB2,MRTFA,ASCL1,MARK4,SLC2A11,AZGP1,ST3GAL5,GYG2,CACNA1D,CAMK2B,USP2,ZFYVE9,SULT4A1,AATK,CSF1,CSF1R,CTIF,GIT2,DRD1,EDIL3,AASS,ELAVL2,IGSF6,PIPOX,FER,FGFR1,SCARA3,DLL3,GPR37,HPSE2,IGF1,IL11RA,KHK,MGAT3,CD200,NF1,PDE1C,PLXNB1,PNMA3,SAMD9,CCDC40,TTLL7,RIT2,ASIC4,ASAP3,PKNOX2,SLC11A1,SOX10,HECW1,WSCD1,HEY2,TMOD1,WIPF1,KCNK12" Drug 2373_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADORA1,ANK3,APBB2,ASPH,ATP2B2,BMP7,SCAPER,CACNA2D1,NRXN1,ABCG1,PPP1R16B,RIPOR2,MFAP3L,ST8SIA3,EEF1A2,SGK2,EFNA3,LPAR6,DMTN,FGFR3,KHDRBS3,SIGLEC8,ALDH1L1,ADAM28,CACFD1,ATXN2L,ICA1,KCNJ3,KHK,LMO1,TAGLN3,NPPA,SLC11A2,MINDY2,PRKCZ,CNNM2,PTPRH,GAL3ST4,RNASEL,EPN2,LIMS2,FAM214B,SLC20A2,ZHX3,ZSWIM8,RBM26,TROVE2,DNMBP,TCF7L2,TRIM2,CRTC1,R3HDM1,ZMYND8,REEP1,EMSY" Drug 4745_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "APC,ARSE,N4BP2L1,LDLRAD4,CACNG1,HIP1R,ASIC3,DNAJB5,LY86,ABI3BP,TCEAL2,CPS1,CNTNAP2,CYBB,RASSF2,MAML1,DAPK3,MFAP3L,DMPK,DUSP9,SNX29,HIPK3,HEYL,PTK2B,OGA,GAB1,SRCAP,GNAO1,GRM7,GSTM5,GUCY1A1,KCNH2,KIT,MDFI,NTRK2,PDE1B,PLTP,PKN2,RELN,CNTLN,RAD52,RYR1,RASA3,SH3GL3,SLC1A2,RPH3A,KANSL3,SLC6A9,MYH15,ARHGAP26,PHLDB1,SYT5,VIPR2,WIPF1,PRDM10" Drug 4625_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SLC12A5,NR0B1,PLA2G6,BRINP2,KIF1A,NRP2,IL33,CFAP410,THSD7A,HIP1R,SH2B1,ARHGEF10,PDE4DIP,RIMS2,INTS1,CNIH3,MFAP3L,DRP2,EIF4G2,COQ7,APC2,FAM198B,CORO2B,HPCAL4,ERGIC3,TBR1,GAB1,GABRA5,GPM6A,GPR22,GRM7,KLF12,TLX1,ICA1,KIT,NOS1,P2RX7,PDE4B,PIK3R1,ENOX1,TCP11L1,RTN1,TRAPPC13,SLC1A6,ARHGEF40,OGDHL,SNCA,FAIM2,MAPK8IP3,ASTN2,TMOD1,SPHK2,PHTF2,SENP7,JPH3" Drug 264_UP MK-886; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "KDM5D,BRAP,ANK1,ARNTL,ATM,FGF17,GYG2,CACNA1I,BTRC,CA8,KALRN,CAMK2A,CLCN4,PDE4DIP,DCAF8,INTS1,DCC,TNK2,ERCC2,FOLR2,B3GAT1,SEPT9,NEU3,TXNL4A,GRM2,PTPRT,SOX21,ARHGAP19,IRF8,ITPKB,KCNJ5,L1CAM,MGAT3,MX1,NNAT,NOS1,DDR2,ODF2,GPR173,CAMKV,PNMA3,POLG,WDR25,SH3TC2,RGS4,FNDC3A,ABLIM3,FAM214B,SLC12A4,IFT122,PHLDB1,AJAP1,TPD52,MPPE1,JPH3" Drug 2638_UP Mimosine [500-44-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADD2,AK2,BIN1,APBB2,CDK13,ALDH4A1,CFLAR,SYNJ2,LDLRAD4,CA4,CACNA2D1,CAMK2B,CDH2,CHRNB2,SULT4A1,HINFP,JAKMIP2,MAGI2,SHANK1,SLC12A6,TENM1,ELN,ZNF589,FOXG1,SEMA4D,GAD1,GAP43,TMEM8B,MALT1,GNAL,IL6R,ITIH2,KCNJ5,LSS,NELL2,OPRL1,PDE3B,PPP2R2B,CEP41,RGS12,SEMA6D,ANKRD6,SMARCD3,SOX2,SPTAN1,IQSEC2,EXOC7,TCF7L2,SPX,TMOD1,VLDLR,WIPF1,SLC30A4,SLC17A7,PHTF2" Drug 2_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ADD2,APAF1,APC,PDE8B,AZGP1,KSR1,BMP7,CCKBR,CBFA2T2,CHRM4,FADS2,AKAP7,BRINP1,TSPAN5,ING4,MRNIP,CALCRL,EPHB1,ZNF589,FGR,FHL1,FLNC,FAM49B,NSG1,GABRA4,SRCAP,GRIA4,FAM107A,PADI2,HMX1,ICA1,IL6ST,MGAT3,NEK1,NF1,NTRK3,OPCML,PLCD1,POLG,PRODH,MTMR10,RIPOR1,GAL3ST4,TCP11L1,FOXRED2,AMBRA1,FNDC3A,SLN,WDTC1,LMO3,PRRC2C,KAZN,EXOC7,TNS1,SEZ6L" Drug 5064_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "CNTNAP1,APBB2,EPB41L5,ALDH4A1,BACH1,SYNJ1,CLU,STOML1,ARMC8,SLC4A8,CSNK1E,KIAA0513,SIRPA,RUSC2,ATN1,EDNRA,HIPK3,ING4,EN2,EPB41L1,LRRC23,CDKL3,ETV1,B4GALNT1,TMEM8B,SESN1,USP19,GLS,TDRKH,GUCY1B1,BACH2,SHISAL1,KIF2A,KIF5C,MEF2C,SCAMP5,NF1,NUMA1,OGG1,ZSCAN2,RAP1GAP,AMBRA1,DZIP1,PDZD2,VAMP1,ASTN2,SYNE1,ARHGEF12,CRTC1,TK2,TPM2,CADM1,ZNF32,MAP3K12,DPF3" Drug 2909_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ACTN2,AGT,AMPD3,CDC42BPA,APBB2,NCOA1,CA8,CACNA2D1,SEPT7,CDH8,DCLK1,EPS15L1,PICK1,DNAJC6,CNIH3,DNM2,SHANK1,EFNB3,SORBS3,CEND1,AFF2,SEPT9,ALDH1L1,GLYR1,GNG4,KLF12,VSIG4,HNMT,TJAP1,AFDN,ADAM22,TAGLN3,OMG,PAH,PDE4D,PENK,NLE1,PLCD1,CEP41,PTAFR,RGS10,EMID1,CNKSR2,EPN2,SLC8A2,SLC11A1,DOK5,ZC3H13,TROVE2,TNS2,CRB1,UGT8,CAB39L,PCBP4,ADAMTSL3" Drug 2360_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DOC2A,SEMA4G,N4BP2L1,KSR1,BMP7,CALB2,CD86,CD38,TAOK2,CPS1,CREM,FEZ1,PDE4DIP,PPP1R16B,ARHGEF4,SNPH,KIAA0513,ZNF337,MBNL2,MRNIP,COQ7,MTSS1L,KIAA1109,FHL1,PDLIM5,PRELID3A,SIGLEC8,INPP5K,GLS,GPR19,SPACA9,PTGDR2,KCNJ5,KCNK1,MAG,MEF2C,GIT1,NF1,OLR1,PDE4B,ST8SIA5,PPP2R2B,PTPRE,RFX2,RGS3,KCTD17,SH3BP2,SLC1A7,SPTAN1,KIF1B,RBM26,SS18,CAMSAP2,TK2,FAM13C" Drug 2170_UP Solasodine [126-17-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "SYN3,CDC42BPA,DDO,BMP7,CACNA1I,C5,CFAP410,CBFA2T2,SYNGR3,CACNA2D2,TAOK2,ABI3BP,CRY2,ABCG1,ABCC9,SORBS3,ELN,NCALD,FOXF2,AGAP2,PDLIM5,PRELID3A,ZMYND11,SIGLEC8,SEPT9,KCNMB4,GNAO1,GPM6B,GSN,HTR2A,KCNMA1,MAP4,MEF2C,ADAM22,MX1,MYCN,NPPA,P2RY1,TREM2,SLC25A23,MTRF1L,RAB3IL1,SUSD4,PREX2,PKNOX2,SHANK2,SLN,MAPK8IP3,FAM168A,WSCD1,DOCK9,ATP13A2,TPM1,PRMT8,FAM155A" Drug 5638_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "TRMT9B,CDK10,PDE8B,MARK4,ATP2A2,SYNJ1,CACNA1I,CBFA2T2,CHRNB2,TAOK2,STOML1,SULT4A1,SLC4A8,ARHGEF10,PDE4DIP,SDC3,RABGAP1L,CDON,DRD1,VPS13B,DMTN,IGSF6,FHL1,GPR153,GAD1,INPP5K,GNG3,GNG4,RNFT2,INPP5B,ITIH2,KCNMA1,MSI1,ZNF862,PDE4A,PIK3CD,PLPPR1,ATG16L1,FAM184A,CARF,ABLIM3,DOK5,ZHX3,FCHO1,ATP11A,ROBO3,TBCEL,TCF7L2,PCDHA5,TMEM121,ZNF34,TPD52,PLPPR2,ZNF711,SLC17A7" Drug 6096_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "AP2A2,ALCAM,MRTFA,AMT,APBB2,APP,ARHGDIG,CAPRIN2,ALDH4A1,CFLAR,SYNJ2,GYG2,CACNA1I,CA12,CAMK2G,MAGI1,FOXN3,FAM189A2,CRMP1,PDE4DIP,RIMS2,MAML1,GIT2,RABGAP1L,KBTBD11,DRD1,RCAN1,DTNA,DUSP9,SORBS3,C3orf18,DLC1,FHL1,SRCAP,GNAS,HSD17B1,ITIH2,IPO5,MMP16,NDUFA5,NEK1,NPTX1,NTRK2,NUMA1,NECAB2,RGS3,ZNF821,SNCA,EMC1,MAPK8IP3,ROBO3,TBCEL,TPM1,ZKSCAN5,TIGD6" Drug 4348_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RALGAPA1,ASIC1,ADRA1D,AP2A2,APBA2,APBB2,APC,EPB41L5,PLA2G4C,ATM,ARHGEF7,FUBP1,CHRNB2,RAB28,PICK1,SLC4A7,TBC1D5,SMG7,RABGAP1L,HIPK3,FCF1,ING4,LRRC23,OGA,TRAF3IP2,RND1,HTATSF1,GNG4,STON1,GRIK5,KHK,MAP4,MDM4,MIA2,NEK1,RETREG1,LRP12,ELOVL2,CCDC40,ATG16L1,WDTC1,ZHX3,TTBK2,ATP11A,TBL1X,WSCD1,TCF7L2,ZEB1,AHCYL2,HEY2,TMOD1,TMPO,FLRT2,EMSY,EVI5" Drug 3110_UP Ketorolac tromethamine [74103-07-4]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "ASIC1,ADCY6,ADGRF5,LGR5,MPDZ,CDK5R1,CDH10,CHRNB2,ZFYVE9,SLC4A8,GPRASP1,DAPK1,SV2B,CDON,ATN1,E2F5,CELSR3,TNK2,LRRC23,STX2,TLR7,CAMSAP1,KHDRBS3,GAB1,GABRA2,SEPT9,GATM,GRIK5,KCNJ4,KIFC3,MGAT3,MPP2,MSR1,NNAT,NRCAM,PFKFB2,LRRN3,PTCH1,FAM120C,SYNDIG1,RYR1,FOXRED2,ASAP3,PALLD,SOX2,IZUMO4,SPTB,SEPT8,AJAP1,ATP13A2,GPR161,TJP1,TLL2,RUNDC3B,ZIC3" Drug 5617_UP Dipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "DPF1,NDRG2,CD86,RAB33A,CLCN4,CABP1,NCOR2,RASSF2,RUSC2,SPOCK3,DMD,HS3ST2,APC2,FGFR1,TMEM8B,SRCAP,C1QL1,POLL,GRIK5,GRIN2C,NR3C1,ATXN2L,KCNJ5,KCNMA1,KCNQ3,TAGLN3,PCBP3,CAMKV,PDZRN4,C19orf57,CNNM2,CNTLN,CCDC40,GAL3ST4,RFX3,RGS10,MYH14,ASAP3,CNKSR2,SLA,SLC1A7,PKNOX2,TSNAXIP1,PEG10,MCF2L2,ATP10B,RGL1,PHLDB1,DOCK9,CRTC1,TEX15,DNAH7,CHST5,TTPA,XRCC4" Drug 6841_DN Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-05 5.18E-01 1.72E-04 1.95E-03 55 198 "RALGAPA1,ABHD6,ADRA1D,AK2,ALCAM,CDC42BPA,GAS7,FAM131A,CAPRIN2,ATM,CFLAR,CACNA1D,CACNB2,ARHGEF2,CHM,QKI,CTH,GIT2,HP1BP3,EXOG,SLC12A6,DTNA,ING4,RRAGB,KIAA1109,FGFR1,IQCG,SRCAP,GNG4,TDRKH,GRB10,LIG4,MAP4,MBD1,NFYA,SETD4,MAPK7,PRPH,ZSCAN32,RAB3IL1,ARID4A,CCDC25,NEK11,SLC9A5,ZKSCAN3,COA1,SEMA4A,TCF7L2,AHCYL2,TMPO,WNK1,HPS4,SEMA3B,MPPE1,GAN" Drug CID000071158 acamprosate Stitch 1.06E-05 5.21E-01 1.72E-04 1.96E-03 27 74 "ARNTL,SPAG9,CRY2,CSNK1E,GRIN3A,NR1D2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GGT7,GGT5,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,OPRL1,SLC1A3" Drug ctd:C026486 "1,2,5,6-dibenzanthracene" CTD 1.06E-05 5.21E-01 1.72E-04 1.96E-03 179 844 "SERPINA3,UNC5A,ADRB2,EPB41L5,ALS2,DDO,ARNTL,PDE8B,ASGR1,ASPA,ATP1A2,ADAM15,GPR146,CFLAR,BMPR1B,ST3GAL5,C5,MMD2,CA8,PRC1,USP2,CD38,ZNF445,CHN2,JAM2,NRXN1,NGEF,MAP4K4,ABI3BP,ZNF521,CP,NSL1,NECTIN3,CLOCK,HAPLN1,CRY2,CRYM,CSF1,APPL1,GREB1,CTNND2,DCAF4,DBI,ARMCX4,PITPNC1,HEPH,SRGAP3,SLC29A4,NR1D2,FAM57B,RCAN1,ARRDC4,EDNRB,SYT15,HEYL,KLHL5,TMTC1,SORBS3,ERBB2,RCSD1,F3,FAM198B,FGF1,FGFR3,BAIAP2,MAD2L2,FHL1,POLK,ZMYND15,TRIM16,CGREF1,GAP43,GCK,GDF1,GPR162,PCDH17,LYVE1,RND1,CCDC184,RAPGEF4,PLCD4,SERP2,GUCY1A2,FAM107A,ATG4C,HLF,HMGCR,HNMT,CELF5,IGF1,IGFBP1,NKD1,DISP2,ZNF385B,ITPKA,KCNB1,KCNN2,KIT,LAMA2,STMN1,LIFR,LMO2,MAPT,TM6SF1,CD200,ERICH3,SAMD5,MSR1,THYN1,MYCN,P2RX7,P2RY1,ZDHHC22,PAH,PAK3,TMOD2,PFKFB3,ABCB1,SERPINE2,ANLN,PIK3R1,RASGEF1B,HYDIN,LAMA1,MTMR10,PTPRG,PTX3,PID1,RAD52,RASGRF2,RGS3,RGS12,LGI2,ROBO2,GLDN,EMID1,HUNK,SLC30A10,HSPA4L,SH3GL3,HKDC1,BCAN,ZNF365,PEX26,SNCA,SCN3B,ENKUR,SPP1,ZNF423,ARHGAP26,TAB2,THSD1,ST5,INKA2,SULF2,VPS13A,KAZN,TMEM136,TRIM2,PCDHB7,PCDHAC2,GPRIN3,AHCYL2,DNAH7,ZMAT3,HHIP,THRA,RASD2,CHST5,AMACR,TUBB2A,TMEFF2,FAM181B,CLDND1,ZNF23,ZBTB16,REEP1,GDPD5,SSPN" Drug CID000162753 IHC-64 Stitch 1.07E-05 5.22E-01 1.73E-04 1.97E-03 16 33 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG2,PKD1,RYR1,RYR3" Drug CID000190902 CNS 1145 Stitch 1.07E-05 5.22E-01 1.73E-04 1.97E-03 16 33 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG2,PKD1,RYR1,RYR3" Drug 4369_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-05 5.26E-01 1.74E-04 1.98E-03 52 184 "NDRG2,FZD9,TRMT9B,PLA2G4C,MARK4,CADM3,CALB1,CAMK2B,USP2,CNTN1,CRYM,NOS1AP,DRD1,DTNA,EDN1,SGK2,EGR3,KCNMB2,REEP2,FABP7,DLC1,GPR153,GAD1,ALDH1L1,GRM8,GUCY1A2,HTR2A,KCNN2,PCBP3,PGAM2,PIK3CD,PLCD1,MINDY2,PTHLH,RFX2,SGK1,HECW1,PEG10,ZC3H13,CDK19,ATP10B,AJAP1,ACSBG1,POPDC3,KAZN,TBCEL,TNS1,UGT8,DNAJC12,VLDLR,LAT2,SLC30A3" Drug 2669_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.07E-05 5.26E-01 1.74E-04 1.98E-03 52 184 "ABHD6,MTUS1,APBB2,APC,ARHGAP5,ALDH4A1,ST3GAL5,SGCE,HIP1R,RAB26,CREM,PDE4DIP,DZIP3,USP6NL,DOCK4,RIMS3,DNAJC6,GSDME,MAMLD1,TSPAN5,FAM13A,MBNL2,LPAR6,TLR7,PDLIM5,STON1,GSN,IFI16,ITGAM,KIF5C,MEF2C,NCAM1,PCDH9,SERPINI1,PMP2,PMP22,PPARA,SATB1,ITSN1,ELOVL4,RGL1,STXBP1,MTCL1,PJA1,DNMBP,TCF7L2,TRIM2,RPGRIP1L,RBFOX2,TRPS1,MAP3K12,PHTF2" Drug CID006857364 AC1OAGGW Stitch 1.10E-05 5.41E-01 1.79E-04 2.03E-03 56 203 "BIN1,DGKZ,GPAM,DGKD,ARHGDIA,BTK,CALM1,DGKI,SEPT7,CDC42,CRLF1,CHRM1,CLTC,PLCXD3,DGKB,DGKG,SNAP91,DNM1,DNM2,DNM1L,PHC2,EPB41,EPB41L1,EPB41L2,FECH,ACTL6B,GAP43,PLCD4,GSN,IL1RAPL1,NXPH2,HPCA,KCND1,NRGN,OCRL,PDGFRA,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,EPN1,PPP2R2B,PRKCB,PRKCG,PTK2,RDX,KCNIP1,EPB41L3,PLCB1,DNMBP,ACTR6,TNS1,TRH,VSNL1,PLD4" Drug 5248_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.13E-05 5.54E-01 1.83E-04 2.08E-03 53 189 "ALCAM,SCAPER,BTRC,CAMK2G,MAGI1,TAOK2,QKI,NECTIN3,LRIG1,GREB1,DOCK4,RIMS3,RABGAP1L,RCAN1,DTNA,RBM12,EPB41L2,PDLIM5,OGA,TRAF3IP2,SRCAP,GHR,TXNL4A,GLYR1,RAB30,EML4,BRINP3,INPP5B,JAK2,KCNJ3,MEIS1,KITLG,MMP16,SLC11A2,NUMA1,PIK3R1,MBOAT7,PKIA,CEP97,LGR4,BTBD7,PHLDB1,PLCB1,TCF7L2,PSD3,TMPO,KAT6B,TRPS1,SSBP2,ZBTB14,EPM2A,ST7,RNF170" Drug 6380_DN STOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "DPF1,LTBP4,APBB2,APOC1,ASPH,ATP1A2,STX16,ADAM15,FUBP1,GYG2,CACNB2,CNTNAP2,ERC2,DCAF4,C2CD2L,MAGI2,DTNA,FCF1,EGFR,LPAR6,COQ7,ETV1,ZNF589,FGF1,FGFR1,ANKFY1,CPLX2,GPM6A,GRIK5,IRF8,KCND3,NEK1,NTRK2,NUMA1,PLEC,TNPO2,MINDY2,RAD52,RGS12,RYR1,ASAP3,SLC11A1,RIMS1,EMC1,IQSEC2,DDN,TCF4,DMXL2,TCF7,TPM2,TRPC3,HIRA,NT5M,SENP7" Drug 3988_DN Cinchonine [118-10-5]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ASIC1,ARID1A,ADORA2A,APOC1,MADD,ARRB2,ALDH4A1,SYNJ2,DNAJB5,RAB26,PICK1,EDRF1,CTIF,MFAP3L,PLPPR4,DLG3,CDON,ATN1,EFNA3,MBNL2,ENO2,ETV1,DLC1,ST3GAL6,ZNF589,MSL3,POLL,SHISAL1,ITPKA,MBD1,MN1,ADAM22,NUCB1,PBX1,PRKAR1B,WDR25,RAD52,ZCWPW1,SUGCT,IL17RB,SELL,FRMPD1,ASAP3,SLC1A7,SLC6A9,SMARCD3,TSNAXIP1,DDN,THSD1,THRA,LMF1,KCNAB1,UBE3B,NUP214" Drug 2735_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "SLC12A5,C1QTNF3,MRTFA,APAF1,FAM131A,PPP4R4,CASK,FOXN3,QKI,HOMER3,COL9A2,CREM,SLITRK5,CTNND1,USP6NL,DTNA,E2F5,HIPK3,SIDT2,EFNA3,EGR3,KAT8,ZNF589,PRKAG2,IQCG,NBEA,INPP5K,WASF3,LILRA2,GPR22,IL6ST,IL11RA,MEF2C,NINJ2,CCSER2,RETREG1,RC3H2,POU6F1,ZFHX4,TCP11L1,CLIP1,SLC1A3,TMCC1,TROVE2,ATP11A,ADGRL3,TCF7L2,AHCYL2,ZNF34,TPM3,TRPS1,SSBP2,ZNF225,URM1" Drug 990_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "AK2,APC,APP,CDC14B,CFLAR,SYNJ2,CCNT1,B4GALT6,ABCG1,FEZ1,CSNK1E,SOCS5,RUBCN,GPRASP1,DCAF8,KIAA0513,GIT2,DLG3,CELSR3,PHF20L1,EIF5,COQ7,DENND4A,OGA,INPP5K,SRCAP,ZNF276,DIDO1,NR3C1,AGBL5,MAP4,SCAMP5,MBOAT7,PRKACB,TMEM104,ZCWPW1,RGS3,MYH14,PAQR6,FOXRED2,ZNF365,PEX26,SCMH1,UHRF1BP1L,KDM4C,CEP68,TACC1,EXOC7,TCF7L2,ATP13A2,TRPC1,LMF1,NDRG4,MPPE1" Drug 607_UP butein; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "BRAP,LTBP4,BIN1,PDXK,ALDH4A1,SLC4A4,CCNT1,CBFA2T2,KIAA1549L,DCT,DYRK1A,FAM13A,EGR3,CDKL3,FABP7,GAB1,SEPT9,BRD8,HPGDS,GPR19,GRIK5,GRIN2C,GRM1,GRM2,PADI2,KIFC3,VWA5A,MAPT,MBP,MITF,NAP1L2,NFIX,NNAT,NRGN,PDE1C,FAM120C,RIPOR1,CCDC40,C1orf54,PRR5L,SYNDIG1,PAQR6,CXXC4,RIMS1,WDTC1,SPART,PRRC2C,ANKRD12,AGTPBP1,HIF3A,SEZ6L,ZNF23,MAP3K12,GJC2" Drug 3302_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ACTN2,KIAA1324,APLP1,BTRC,ARHGAP33,SULT4A1,CNTN1,SLC4A7,TCEAL2,CRMP1,NOS1AP,BRINP1,JAKMIP2,MFAP3L,DMPK,DRP2,HIPK3,EFNB3,PLXNC1,ZNF589,SRCAP,RAB30,GPM6B,GPER1,ATXN2L,KCNQ3,MAPT,MOBP,ZNF862,PDE3B,PIK3CD,PLCD1,PLXNB1,PACSIN1,MAPK8,CNNM2,PTHLH,PAQR6,KCNIP1,FAM214B,SLC11A1,SNCA,INKA2,TBCEL,SLC19A3,CRTC1,THBS4,CABIN1,PDIA2,VIPR2,ZNF189,DNALI1,EVI5,SENP7" Drug 2391_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ACTN2,MTUS1,PPFIA3,PRX,ARRB2,ALDH4A1,BTRC,RUNX1T1,NEURL1,TPP1,SULT4A1,COL9A2,CRMP1,CSNK1E,PDE4DIP,DGKG,CNIH3,MAGI2,DSCAM,EDNRB,EPB41L1,STX2,BAIAP2,HPCAL4,FYB1,INPP5K,GNAO1,GPD2,LILRA2,CACFD1,GSTM5,GUCY1A2,KLF12,ICA1,KCND3,LSS,MSR1,NF1,NOS1,MINDY2,PPP2R2B,MAPK8,RGS3,FBXO11,SP4,IZUMO4,PEG10,SPTB,STX1A,TBCEL,CRTC1,TRPC3,TUBB1,RPRM" Drug 6673_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "DPF1,ASPHD1,FZD9,ADGRF5,CDC14B,SYNJ1,BTRC,CAPN3,MTMR7,CBFA2T2,SCARB1,NRXN2,PICK1,PDE4DIP,CNTNAP2,ST18,SRGAP3,TRAPPC9,EGFR,PLEKHA1,ING4,IGSF6,ST3GAL6,CAMSAP1,ERGIC3,GAD2,FERMT2,KCNMA1,ADAM11,MDM4,KITLG,AFDN,ADAM22,BCO1,PDE4A,PGAM2,PPP2R2B,MAPK8,PRPH,ENOX1,TCP11L1,SH3BP2,ZNF334,SLC15A2,ZSWIM8,IZUMO4,HECW1,SEMA4A,ARHGEF12,TPM3,ZNF24,ZNF225,PRDM2,KCNAB1" Drug 3245_UP Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "NDRG2,NME5,BIN1,CDC42BPA,APLP1,PPP4R4,PDE8B,MARK4,SCAPER,BAIAP3,LDLRAD4,CACNB2,TPP1,CNTN1,WHRN,CRMP1,DMPK,DYRK1A,MTSS1L,F3,CAMSAP1,GABRA2,GAD2,DISC1,STON1,GPER1,AFDN,MOBP,MSR1,NDUFA5,CDK18,PDE4D,MAPK7,PLPPR1,RAB3IL1,RGS12,MYH14,RPS6KA2,ASAP3,SLC1A2,SHANK2,SMARCC2,ARHGAP26,CLSTN2,SUPT5H,ARC,POPDC3,ZNF34,DAAM2,CDK20,WBP2,VLDLR,KCNK12,ITM2C" Drug 5880_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ADRA1D,MRTFA,N4BP2L1,ADAM23,CFLAR,CACNG1,CBFA2T2,SYNGR3,NEURL1,ARHGEF2,CDH10,DNAJB5,WHRN,CSF1R,VCAN,CTH,ARHGEF4,DAPK3,TRAPPC9,CNNM1,AASS,DENND4A,GLYR1,MSL3,GPM6B,GPR37,FICD,ICA1,TJAP1,PDE2A,PLCD1,PTCH1,PTPRH,TTLL7,RNASEL,NEK11,EMID1,FAM214B,ZNF334,SLCO1A2,KDM4B,NMNAT2,ARHGAP26,TSPYL2,DDN,CEP68,COBL,TACR1,SYNE1,SSBP2,HIRA,WNT7A,PRDM2,SLC17A7" Drug 4320_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "BRAP,PLA2G6,MRTFA,APBB2,ASPH,SRSF11,TAOK2,PLAA,CRMP1,CSNK1E,SPOCK2,SMG7,ATN1,EPB41L1,FOXG1,GABRA2,MSL3,TDRKH,CACFD1,GSTM5,MAP4K5,RASSF8,ELOVL5,AGFG1,HSD17B1,IFI16,IL6ST,INPP5B,MAP4,MDM4,MMP16,MX1,ZNF862,PENK,STRN3,MINDY2,RAB3IL1,KIRREL1,MCMBP,DZIP1,CCDC88A,DOK5,SAMSN1,ATP11A,SMG6,EHBP1,PSD3,TMPO,VIPR2,WIPF1,SPHK2,WNK1,PRDM2,KAT6A" Drug 3684_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "SYN3,ACTN2,NDRG2,ADCY6,ADD2,FAM135A,GAS7,PPP4R4,ASCL1,DNAH17,DDX3Y,ATP1A3,SLC4A4,CHRNA4,CHRNB2,NRXN3,ZFYVE9,VAX2,CTNND2,ATN1,FCF1,DLC1,ANKFY1,TBR1,GAB1,ATP8A2,RND1,GRIK5,NXPH3,ATXN2L,MMP16,CD200,NNAT,CLDN11,CAMKV,MINDY2,PTPRB,CCDC40,RGS4,CSRNP3,NTNG1,FBXO11,SLC15A2,SOX15,NPAS3,INKA2,VAMP1,PCDHGA10,CRTC1,HIRA,UCHL1,SPHK2,EMSY,MVB12B" Drug 4537_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "MRTFA,DGKD,DDO,LGR5,CDC14B,ATP2A2,CACNA1D,CBFA2T2,SCARB1,LHX2,CRY2,CTNND2,ST18,OPTN,SORBS3,CEND1,FGF1,FLT1,FYB1,GAB1,CHL1,DISC1,GFER,RND1,ATF7,GPR22,LPAR4,JAK2,SMAD1,MAN2A2,LYRM9,NEUROD1,PENK,PMP2,POLG,PPARA,MAPK10,PRPH,PTAFR,C1orf54,RGS3,MRAS,SLC11A1,SLN,SOX15,ZHX3,VAMP1,ARC,PCDHA5,FLRT2,PRDM10,NAV3,EPM2A,SENP7" Drug 4538_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "CDC42BPA,APAF1,APBB1,CADM3,ADAM23,NRP2,SYNJ1,FUBP1,SCARB1,CHM,SULT4A1,RAB26,HOMER3,DAPK3,MFAP3L,DMPK,CDON,DRD1,EDIL3,SGK2,IRAK4,CEND1,DLC1,HPCAL4,GABRA2,GPR22,GRM8,HSF2,IL12A,KCNMA1,KHK,LIG4,MMP16,NF1,NOVA2,PDE4A,ENPP2,PLCD1,LRRN3,VPS13C,PTPRH,RAB3IL1,RASGRF1,KCTD17,FOXRED2,FNDC3A,KIF13A,SOX15,VAMP1,GPR161,TK2,TMOD1,TPM2,EVI5" Drug 4626_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "DPF1,ASPHD1,ADCY6,ANK3,N4BP2L1,KSR1,FUBP1,CBS,ADGRG1,CHN2,TAOK2,HAPLN1,PDE4DIP,CNIH3,DRD1,EDNRA,SIDT2,RASGRP2,SPEG,ETV1,PRELID3A,NSG1,FYB1,CYP46A1,GPM6B,AP4S1,PTGDR2,BACH2,ELOVL5,IL6ST,KIF2A,MMP16,TAGLN3,DDX25,CNOT4,PLCB2,SPATA6,FA2H,POU3F2,PPP2R2B,SNRK,TMEM231,PBRM1,NEK11,TCP11L1,EMID1,ASIC4,KDM4B,PHLDB1,KLHL4,TRPC3,FLRT2,EPM2A,DPF3" Drug 4951_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "NDRG2,NME5,ALK,PPFIA3,MARK4,SLC2A11,CAMK2G,CBFA2T2,NEURL1,ARHGAP33,CHRNA4,SULT4A1,CSF1R,DCAF4,SPOCK2,BRINP1,C2CD2L,SGK2,SIDT2,CORO2B,CAMSAP1,FYB1,ALDH1L1,KLF12,TJAP1,KCND3,KCNH2,MAP4,AFDN,NOVA2,PCDH9,MTRF1L,ZNF493,ZMAT4,KCNIP1,SLC2A5,PKNOX2,ZNF415,DOP1A,WDTC1,ZC3H13,SPTB,IQSEC2,TBCEL,SMG6,WSCD1,PCDHGA10,HIF3A,THRA,TK2,VIPR2,WIPF1,SLC30A4,SLC17A7" Drug 222_DN "LY-171,883; Down 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ASIC1,NDRG2,ADCY2,ADD2,ALK,MYRF,CA12,CHN2,SLIT2,CLCN4,CLIP3,AATK,FEZ2,JAKMIP2,AK5,DMPK,DYNC1I1,DYRK1A,EDNRA,EFNB3,CALCRL,ETV1,ANKMY1,PTK2B,ZMYND10,FGFR1,FHL1,FYB1,DISC1,RUNDC3A,GLI2,GNAL,GNAO1,GRB10,GUCY1A1,NXPH3,NF1,NTRK3,FXYD1,PPP5C,MAPK3,C1orf54,HUNK,FERMT1,PPP4R3A,SON,HECW1,ZC3H13,SPART,PRRC2C,COBL,ADGRL3,GPR161,BEST1" Drug 2469_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "NDRG2,MRTFA,ADAM23,ADAM15,SYNJ2,CACNA1A,CLCN3,TPP1,NIPBL,RCHY1,CREM,CRY2,VCAN,TBC1D5,RIMS3,CNNM1,TUBD1,PLEKHO1,LRRC23,NCALD,F5,KIAA1109,GALC,INPP5K,HTATSF1,POLL,TJAP1,KIF2A,MDM4,MEF2C,SCAMP5,ZNF862,NF1,NFYA,CNOT4,PKN2,PTCH1,PTN,RAD52,MYH14,TCP11L1,RXRA,MRAS,RASA3,SCG5,ELMO2,ZCCHC24,RAP1GAP2,ATP11A,TCF7L2,TRPS1,LAT2,NLRP3,SENP7" Drug 6644_UP Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "ACHE,SPARCL1,LGR5,ATM,ATP6V0A1,BMPR1B,ADGRG1,TAOK2,CLCN4,AKAP5,ENTPD4,ARHGEF10,BRINP1,MFAP3L,DTNA,EDN1,SIDT2,OLFM1,FLT1,NSG1,OGA,ALDH1L1,GPR17,HSD17B1,C2orf72,ITGA7,ITIH2,KCND3,KCNJ5,MAPT,MMP16,ADAM22,NPY,GPR85,PENK,RETREG1,PMP2,PPARA,LRRN3,DCHS2,ZSCAN32,ACSS3,SUGCT,ZFP2,RASA3,SH3BP2,SLC11A1,TACR1,DOCK9,TPM1,HIRA,NT5M,STMN4,JPH3" Drug 2838_UP Etifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "PLA2G6,BIN1,PPFIA3,PLA2G4C,DDX3Y,ATM,CFLAR,BAIAP3,ADGRG1,ZFYVE9,PICK1,NCOR2,MICAL2,SPOCK2,ZNF804A,RABGAP1L,TSPAN5,EGR3,TNK2,FGFR1,CAMSAP1,AGAP2,FAM49B,SEPT9,MSL3,GRIK5,IL6ST,INPP1,JAK2,KCNN1,MAOB,MAP4,MOBP,ADAM22,BCO1,SLC11A2,PDE4B,LRP12,MINDY2,PPP2R2B,PRKAR1B,RAD52,EPN2,PKNOX2,KDM4B,SOX3,BEX1,ZC4H2,SMG6,TRPC1,ZMYND8,UBE3A,SPHK2,EPM2A" Drug 6827_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "MRTFA,ANK1,CDC14B,ATP2A2,SYNJ1,GYG2,CACNA1A,CDH18,CLGN,ADGRG1,CLCN4,AKAP7,RCHY1,CRMP1,PDE4DIP,DTNB,ELAVL2,LRRC23,FGF1,FGF13,ERGIC3,TBR1,ATP8A2,LYVE1,GLYR1,GPR37,ITGA7,KCNC1,KCND3,MIA2,MOBP,NF1,SERPINE2,LRP12,GRAMD1C,ELOVL2,RGS4,TTLL7,ZFHX4,KLHDC8A,TCP11L1,SCN8A,CCDC88A,SLC11A1,SHANK2,ARHGAP26,KAZN,DOCK9,CRTC1,PCDHA3,TMOD1,TNS1,TRH,KAT6A" Drug 6066_DN Skimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "NDRG3,AK2,ALCAM,SRPX,AMT,APBA2,FAM131A,ALDH4A1,CADM3,MTMR3,GYG2,CBFA2T2,ARHGEF2,PICK1,CNTN1,ENTPD4,JAKMIP2,HIPK3,EFNA3,C3orf18,STX2,NCALD,ZNF589,KIAA1109,FGFR1,IQCG,DISC1,SEPT9,TXNL4A,POLL,GNAS,IL6ST,KPNA5,IPO5,LSS,MID1,MMP16,ADAM22,NF1,PDE4B,RAD52,ZNF821,SLC20A2,ZCCHC24,CDK19,ST5,FAM168A,KIAA0930,CHST8,HIRA,VIPR2,WIPF1,ZNF74,GDPD5" Drug 7153_DN Pyrithyldione [77-04-3]; Down 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-05 5.81E-01 1.91E-04 2.17E-03 54 194 "APBB2,PPFIA3,ASPH,SLC4A4,CFLAR,ST3GAL5,MTMR3,B4GALT6,NRXN3,ENTPD4,NCOR1,DZIP3,GIT2,C2CD2L,SGSM2,DNM2,DPH1,EDNRA,LPAR6,IRAK4,ELAVL2,F8,ATP8A1,ZNF589,IQCG,B4GALNT1,INPP5K,SESN1,POLL,GPD2,GIT1,NF1,PAK3,PLCD1,PTPA,ROGDI,RGS3,TCP11L1,WDR37,SMARCD3,TNIK,WWC1,TCF4,KIAA0930,TCF7L2,TMEM121,TK2,TRPC1,HIRA,UBTF,LMF1,UPF3A,HPS4,ADAMTSL3" Drug 5950_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.20E-05 5.88E-01 1.93E-04 2.19E-03 51 180 "ABAT,ADRB2,MTUS1,NME5,ARNTL,ST3GAL5,HIP1R,NMT2,PDE4DIP,CTH,NOS1AP,SIDT2,EFNA3,RGS17,DLC1,TESK2,BAIAP2,DPYSL4,SORBS1,FYN,CYP46A1,RND1,GLS,STON1,PADI2,DIPK1A,KIF5C,MAPT,MITF,PCDH9,PDGFRA,ENPP2,SERPINI1,PIK3CD,PRPH,RAB3A,RGS4,RGS10,SH3GL2,SH3GL3,SPATA7,ARHGAP26,THSD1,ELOVL4,RGL1,SYT11,VAMP1,ARC,SYT1,DNAJC12,SLC17A7" Drug DB00849 Methylphenobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00306 Talbutal Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00418 Secobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00463 Metharbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00237 Butabarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00312 Pentobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00241 Butalbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01353 Butethal Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01355 Hexobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01352 Aprobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01496 Barbituric acid derivative Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01483 Barbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01354 Heptabarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB01351 Amobarbital Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug DB00794 Primidone Drug Bank 1.24E-05 6.06E-01 1.94E-04 2.21E-03 8 10 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug 2115_UP Chlorphensin carbamate [886-74-8]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "KCNAB2,ATP2B2,KSR1,CACNA1I,CFAP410,LARGE1,MAGI1,CHM,LHX2,ZFYVE9,CLU,DNAJB5,HOMER3,IQCK,ARMC8,AKAP6,CRMP1,CRY2,ARHGEF4,DLG3,HIPK3,SIDT2,CDKL3,ETV1,ATP8A1,FGF1,FOXG1,FYB1,GLYR1,GNAL,ELOVL5,KCNN1,ADAM22,NOS1,PCDH9,STRN3,PRKAR1B,BCAS3,GAL3ST4,RGS4,SEMA6D,ZFP30,ASAP3,BCAN,CCDC88A,BTBD7,MAPK8IP3,TBL1X,TRIM2,CHST8,TK2,RPRM,REEP1,WNK1,NT5M" Drug 5526_UP Prednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "BEGAIN,CDC42BPA,ATP6V0A1,NRP2,CACNA1D,CACNB2,CAMK2A,SIPA1L1,VCAN,EDRF1,MAML1,DCT,HEPH,HP1BP3,GSDME,DTNA,TNK2,EN2,LRRC23,FHL1,HPCAL4,AFF2,GAB1,GAD1,HBS1L,C1QL1,RUNDC3A,GNG3,PRUNE2,ATXN2L,ICA1,IGF1,KCNMA1,PCSK2,PPP5C,MAPK10,PLPPR1,ATG16L1,SYBU,SMTN,EFHD1,ZSWIM8,PEG10,STX1A,SYT5,ROBO3,WSCD1,DOCK9,FAM189A1,TNS2,TK2,TNS1,FLRT1,KCNK12,SLC30A3" Drug 4636_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "TRMT9B,AMH,AMT,PDE8B,ALDH4A1,CADM3,ADGRB2,BAIAP3,SCARB1,LARGE1,NMT2,AKAP7,MFAP3L,HEYL,ING4,ANKMY1,NRN1,ST3GAL6,CGREF1,HTATSF1,GPM6B,GRIK2,CACFD1,GRM1,DHX35,KCNF1,MT1M,MYT1,NEUROD1,NNAT,PIK3R1,PRKAR1B,PTPRB,TMEM231,RGR,MYH14,PAQR6,FOXRED2,SCN2B,FRMPD1,SLC1A7,SLC6A9,MYH15,WDTC1,ZBTB43,KAZN,KIAA1107,TCF4,ZNF34,TIAM1,RIMBP2,TPM2,EVI5,KCNAB1,EPM2A" Drug 1768_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "EP400,SEMA4G,CADM3,NRP2,MTMR2,CACNB4,INA,CLTB,MAP4K4,SEC31B,CREM,CST3,HP1BP3,KBTBD11,EXOG,DSCAM,PCOLCE2,RASGRP2,PRKAG2,IP6K2,TRMO,GABRA4,ALDH1L1,GRIK5,ITGA7,LIG4,MAP4,NOS1,CNOT4,OGDH,PDE4B,PDPK1,PNMA3,PPP5C,RAB3IL1,SATB1,NTNG1,FNDC3A,FAM214B,SLC12A2,ELMO2,COA1,THSD1,FCHO1,GANAB,EXOC7,THBS4,CBX5,TPM3,LAT2,XRCC4,ZNF32,ZNF142,HPS4,FXR1" Drug 3608_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NDRG2,AK2,AMT,PPP4R4,ATP6V0A1,SYNJ2,CA12,CAMK2B,NEURL1,CLGN,AKAP7,RCHY1,SDC3,CTH,GREB1,DBT,MFAP3L,KBTBD11,ATN1,DTNA,SUGP2,ENO2,ZNF589,FGFR3,SEMA4D,EFCAB2,PRELID3A,CGREF1,INPP5K,GPD2,ELOVL5,IL6ST,JAK2,MAPT,KITLG,NF1,CNOT4,NTRK2,PLCD1,EPN1,PPP5C,MAPK8,TMEM104,MSANTD2,RGS3,PPP1R9A,BTBD7,WDTC1,EMC1,SPTAN1,VPS13A,TBCEL,ZKSCAN5,LMF1,WNK1" Drug 6637_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ACHE,ADD1,PLA2G6,ALK,DDX3Y,ATM,ADGRB2,BMP7,CACNA1G,CACNG1,HAP1,CLDN10,ARHGAP33,CHRNA4,ENTPD4,CNTNAP2,MAML1,DUSP9,USH1C,EDN1,ING4,AGAP2,NEU3,ALDH1L1,PRUNE2,GRIK5,IL6ST,KCNB1,NF1,CNOT4,PALM,GPR85,PROX1,ZSCAN32,PTPRB,TMEM231,ENOX1,KCTD17,EMID1,NTNG1,SLC9A5,KIF21B,KDM4C,SPTB,NPAS3,ATP10B,PHLDB1,SYT1,TPM3,AMOT,LAT2,ZNF24,WNK1,KCNAB1,MVB12B" Drug 258_DN LY294002; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NDRG2,ADD3,BRAP,ADORA1,AMPH,AQP6,EIF4G3,FUBP1,RAB29,CFAP410,SCARB1,CLCN3,HOMER3,PCYT1B,IFFO1,SH2B1,NCOR2,SIPA1L1,ECE2,EXOG,DRP2,RBM12,EFNB3,CALCRL,STX2,FGFR3,SCARA3,CAMKK2,MALT1,GJB1,LILRA2,BTN2A1,KLF12,IRF8,ITPKB,KCNQ3,MBP,MID1,MMP16,GIT1,NPPA,CLDN11,FXYD1,MAPK8,HUNK,DZIP1,PKNOX2,CDK5RAP2,KDM4B,SPART,KAZN,TBL1X,SSBP2,MVB12B,C12orf4" Drug 3113_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ACTN2,NDRG2,AGT,CNTNAP1,ARHGDIG,ALDH4A1,BMP7,CAPN3,HIP1R,RUNX1T1,FRMPD4,MFAP3L,CDON,OPTN,PLXNC1,CD320,BAIAP2,FOXG1,C1orf61,GAP43,SRCAP,GRIK5,GRM8,ATXN2L,KCNH1,MAP4,AFDN,MPP2,MX1,MYBPC1,NOVA2,NRCAM,PDE2A,PDGFRA,PFKFB4,DCHS2,PLPPR1,RASGRF1,GAL3ST4,MAP6D1,RYR1,SHANK2,SNCA,IZUMO4,HECW1,TSPYL2,SYN2,ADGRL3,WWC1,CRTC1,TRH,KCNE5,TMPRSS5,TUBB1,SLC30A3" Drug 6083_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "AMH,ANK1,GAS7,PLA2G4C,ALDH7A1,CA4,CACNG1,RUNX1T1,CDH2,CSF1,ARHGEF10,IPCEF1,DCAF4,TOX,SPOCK2,SRGAP3,DTNB,ELN,LRRC23,RASGRP2,FABP7,FGFR1,B3GAT1,SRCAP,PRUNE2,LPAR4,PCLO,ADAMTS13,GRM2,GSN,SOX21,PTGDR2,ITPKA,KCNB1,KIT,CD200,TAGLN3,MX1,NNAT,NPPA,PCDHGC3,PFKFB2,SERPINI1,CAMKV,C1orf54,ENOX1,ZNF493,ZMAT4,SH3BP2,FAIM2,SOX10,CRTC1,SEZ6L,FLRT2,KCNAB1" Drug 3668_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "RALGAPA1,ADRA1D,MRTFA,CDK5R1,SCAPER,BAIAP3,HAP1,AP4M1,SEPT7,LARGE1,PLEKHB1,PLAA,QKI,PICK1,SH2B1,SDC3,DAPK3,DMPK,SUGP2,VPS26C,OGA,FYN,DENND2A,ZNF276,GPR17,GPR19,CACFD1,KLF12,SHISAL1,INPP5B,SCAMP5,PPP3CC,PTPRN2,RIPOR1,RAB3IL1,CCDC40,GAL3ST4,ROM1,NEK11,ZFP30,ASAP3,FUZ,SLC4A3,ELMO2,SLC20A2,SMARCD3,SPTAN1,SPTB,SS18,ASTN2,CDK20,TPM2,LMF1,NSD2,ZNF32" Drug 2497_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY2,BEGAIN,BIN1,CDC42BPA,PKP4,AQP4,ARHGDIG,DDX3Y,KIF1A,BCL7A,CDK5R1,CACNA1I,CLCN4,FAM149A,NCOR2,ABCG1,CTNND2,KIAA0513,HEPH,DTNA,ECM2,MBNL2,SORBS3,PLEKHA1,HSD17B14,RASGRP2,ERCC2,ZNF549,CDKL3,BAIAP2,CGREF1,ALDH1L1,C1QL1,GPM6A,GPR22,GRIK5,IL6ST,KIF5A,MAP4,MAPT,SLCO1C1,NNAT,NPPA,PCSK2,PDE4D,PFKFB2,POU3F2,PTPN13,FAT4,BCAN,PLCB1,AHCYL2,ATP13A2,DICER1,PRDM10" Drug 6153_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "SPARCL1,LTBP4,BIN1,KSR1,FUBP1,CACNA1I,CFAP410,CACNA1B,CACNG1,MAP7,SEPT7,CHRNA4,LHX2,ZFYVE9,MFAP3L,HS3ST2,ATN1,MAMLD1,SIDT2,OPTN,ING4,ETV1,FGF1,FOXG1,CAMKK2,SIGLEC8,GATM,C1QL1,GSTM5,KLF12,KCNB1,LAMA2,MYT1,NDP,NRCAM,RETREG1,POU6F1,SIDT1,PTPRN2,FAM120C,IL17RB,SLITRK3,ABLIM3,EMC1,ARHGAP26,TBCEL,PSD3,PCDHA5,TK2,SEZ6L,TPM1,BEST1,KCNK12,PLSCR4,PARP11" Drug 4210_DN Diflunisal [22494-42-4]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY6,MRTFA,TRMT9B,BIN1,PDE8B,DNAH17,BRINP2,ADAM23,CA12,KIAA1549L,IQCK,CHD1L,CSNK1E,VCAN,TBC1D5,DAPK3,ATN1,SORBS3,ATP8A1,ZNF589,ZNF44,TMEM8B,SEPT9,GNG4,LPAR4,GRM1,GRM8,HNMT,INPP5B,JAK2,LMO2,PACRG,MDFI,MGAT3,TAGLN3,ODF2,SERPINI1,RETREG1,PLCD1,PLXNB1,PROX1,BCAS3,PTPRB,RAD52,FBXW7,ATXN7,ZNF821,GPR161,ZNF34,THRA,UGT8,ZNF711,NDRG4,EVI5,KCNAB1" Drug 4069_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MTUS1,PPFIA1,AQP4,MARK4,ASTN1,IL33,KRIT1,ARHGEF1,CDC42,LARGE1,CHM,DNAJB5,QKI,LY86,AKAP5,SLITRK5,KIAA0753,PLPPR4,PARD6A,ABCC9,PLXNC1,SORBS3,COQ7,MTSS1L,ETV1,ZNF589,FGFR1,FOXG1,ANKFY1,TRAF3IP2,KIFC3,MEF2C,MYT1,NPR2,RETREG1,EPN1,SPATA6,RALGDS,BEND5,FBXW7,RPS20,CSRNP3,SELL,SLC4A3,FAM214B,SLC9A5,EMC1,ZBTB43,COLGALT2,EXOC7,TCF7L2,R3HDM1,AMACR,UGT8,AAAS" Drug 6069_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "SYN3,ASIC2,ADD2,FZD9,ADORA2A,KIDINS220,ALK,BIN1,ANK1,RGS20,ATP1A3,CACNG1,INA,CDH10,SLC22A6,CLCN4,DCAF4,CYBB,SPOCK2,KIAA0319,DTNB,SEMA3D,FYB1,ZNF44,GAP43,GPR75,HAS2,ATXN2L,SCRG1,KCND3,LAMA2,MGAT3,MSR1,TAGLN3,NPPA,P2RY1,SERPINE2,PPARA,KHDRBS2,RGS12,RPH3A,SLC2A5,ARHGEF40,CXXC4,KIF21B,COLGALT2,PHLDB1,TCF4,CRTC1,SEZ6L,TRPC3,FLRT2,DNALI1,ADAMTS9,KCNAB1" Drug 4375_DN U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "AP2A2,ALK,AMPD3,BIN1,APBB2,ATM,NRP2,GYG2,CACNA1I,LDLRAD4,CAMK2B,SCARB1,HOMER3,CPS1,NCOR2,AATK,CNTNAP2,RIMS2,MFAP3L,DRD1,HIPK3,TNK2,NCALD,DLC1,FGFR3,SRCAP,RUNDC3A,STON1,GRM1,ATXN2L,ITIH2,BCO1,NNAT,PDE4B,GPR85,PLCB2,LRP12,POU3F2,MAPK10,CNNM2,TRIM68,TCP11L1,ZBTB43,SAMSN1,KIAA0930,ZEB1,PSD3,TEX15,TK2,HEY2,DAAM2,TPM2,TRPM2,WNK1,PARP11" Drug 2618_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MTUS1,CDC42BPA,PPFIA3,ARHGAP5,NUMB,ATM,ATP2B1,KIF1A,BCL7A,CFLAR,BMP7,CBR1,PLEKHB1,CLCN3,MAP4K4,NIPBL,COL9A2,CREM,DBT,FBXL5,TRAPPC9,EFNA3,SUGP2,PRRC2B,GPD2,MUM1,DHX35,HSF2,JAK2,KCNH2,KHK,MAPT,MPP2,GIT1,NF1,SETD4,PTCH1,GTDC1,CCDC25,ZNF821,AMBRA1,ZSWIM8,TSPYL2,TROVE2,NXT2,NEK4,TBL1X,TCF7L2,PSD3,UBTF,LMF1,ZNF74,WIPF2,MPPE1,SSPN" Drug 6661_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "SLC12A5,SPARCL1,ATP2B2,ATP6V0A1,RGS11,CFLAR,BMPR1B,CACNB4,CACNG1,KALRN,DNAJB5,IFFO1,MAML1,BRINP1,C2CD2L,AK5,DUSP9,KCNMB2,OLFM1,FOXG1,C1orf61,GABRA3,GAD2,NEU3,GFER,RUNDC3A,CACFD1,GRM2,ICA1,KCND3,MAG,MAP2,NRCAM,RETREG1,ZNF426,ZSCAN32,PTPRO,ZSCAN2,CCDC40,FOXRED2,SLC11A1,RIMS1,ATP10B,PHLDB1,ACSBG1,SEMA4A,PHF24,PCDHA6,FLRT2,VAV2,LAT2,KCNK12,ZIC3,ZNF24,ZNF74" Drug 5686_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,APAF1,APBA2,APOC1,CDC14B,SYNJ1,SYNJ2,CACNA1G,HAP1,FOXN3,DNAJB5,CRY2,PDE4DIP,RIPOR2,RASSF2,MAGI2,ATN1,DSCAM,ECM2,EGFR,MBNL2,FHL1,EFCAB2,GAB1,GALR1,SRCAP,RUNDC3A,TJAP1,IGSF1,MAOB,MYBPC1,MYT1,NTRK2,POU6F1,PKN2,PTPRB,ROM1,SELL,NTNG1,EPN2,ARHGEF40,SLC11A1,SLC20A2,CXXC4,SOX11,ZBTB43,NPAS3,AJAP1,VAMP1,TF,DICER1,TIMP4,ZNF711,EMSY,KCNAB1" Drug 4023_UP Metronidazole [443-48-1]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY2,ADD2,CDK10,CDK13,N4BP2L1,BTRC,ARHGAP33,MAGI1,CHM,RAB33A,TPP1,VAX2,AKAP7,AKAP6,AKAP5,TCEAL2,LRIG1,CSNK1E,SRGAP3,DTNA,ST8SIA3,EDNRA,NRN1,EFCAB2,GAB1,GAD2,HBS1L,NEU3,GLYR1,GNG3,GRK4,GRIK5,HPSE2,ICA1,JAK2,KCNJ5,OCRL,PIK3R1,RETREG1,LRP12,BEND5,RPRD1A,SLC11A1,PHLDB1,ACSBG1,VAMP1,RPGRIP1L,CRTC1,TRO,TUBB1,VIPR2,VLDLR,SLC30A4,PARP6,PHTF2" Drug 959_DN "N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ABR,MTUS1,ANK3,APOC1,APP,STX16,MTMR9,SYNJ2,C5,PLEKHB1,STOML1,QKI,ARMC8,CREM,FBXL5,PARD6A,DTNA,PHF20L1,MBNL2,MRNIP,EZH1,SRCAP,CNTRL,HSF2,KCNF1,KCNJ3,MAP4,MBNL1,MPP2,NF1,CNOT4,NRCAM,SETD4,OXTR,PIK3R1,PLXNB1,MBOAT7,SIDT1,CEP97,CLIP1,FUZ,FNDC3A,ABLIM3,PEX26,DOP1A,DIP2A,VPS13A,SIN3B,AP4E1,KAT6B,RBFOX2,HIRA,XRCC4,HPS4,PHTF2" Drug 4988_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADORA1,KCNAB2,APBB2,CDC14B,RGS20,MARK4,CADM3,CHN2,CLCN4,CRY2,CSF1,PDE4DIP,ARMCX2,DYRK1A,C3orf18,FOXG1,OGA,FYB1,GABRA2,GFER,RUNDC3A,GLRB,LPAR4,GRM8,GSTM5,ICA1,IGF1,KIF5A,VWA5A,KITLG,MID1,SLCO1C1,NUMA1,KCNK10,PIK3CD,PURG,SNRK,RGS4,SUGCT,MYH14,RPH3A,CCDC88A,SOX2,KIF21B,IZUMO4,ACSBG1,POPDC3,ROBO3,TBCEL,SZT2,TK2,CABIN1,TRPC1,UCHL1,NUP214" Drug 5443_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,NDRG3,C1QTNF3,PDE8B,MARK4,KIF1A,SYNJ2,BTRC,QKI,NECTIN3,SIPA1L1,SOCS5,CNTNAP2,DSCAM,SIDT2,EIF4G2,EML1,SCML2,KIAA1109,BAIAP2,ANKFY1,GALC,DISC1,GLYR1,RAB30,GPER1,GRIK5,ELOVL5,HNMT,IL6ST,NDUFA5,NFYA,PDE3B,LRP12,MBOAT7,MAPK8,GON4L,PTHLH,ELOVL2,ZNF365,BTBD7,MAPKBP1,EMC1,KDM4C,MAPK8IP3,PLCB1,MCF2L,EXOC7,IQCE,TRIM2,TMOD1,CABIN1,SMIM8,SSPN,GAN" Drug 3333_UP Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NME5,SEMA4G,BACH1,KSR1,BAIAP3,CFAP410,CLDN10,CCKBR,CDH2,CHN2,TAOK2,LHX2,TPP1,PICK1,AKAP6,TCEAL2,CSF1R,PDE4DIP,CNTNAP2,NOS1AP,SNPH,PHYHIP,ELMO1,CNIH3,EDN1,EFNB3,MBNL2,ATP8A1,KIAA1109,PCDH17,GRIA4,GRIK5,GSN,GSTM5,NXPH3,KCNK2,TM6SF1,NCAM1,PCBP3,PDE3B,PACSIN1,SAMD9,ZDHHC14,RGS12,CNKSR2,SLC1A7,KDM4B,TSNAXIP1,ZC3H13,CLSTN2,HIF3A,TEX15,TRPM2,WIPF1,ITM2C" Drug 2663_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "SLC12A5,MTUS1,LGR5,AZGP1,NRP2,BMP7,CDK5R1,HAP1,CRMP1,OSBPL3,PDE4DIP,DCAF4,USP6NL,EDRF1,SPOCK2,C2CD2L,ATN1,ST8SIA3,HIPK3,SRPK3,VPS13B,FHL1,AGAP2,PDLIM5,NSG1,GABRA1,GABRA2,GAD2,ERAP1,GNAO1,GRIN1,GRM7,MEF2C,PDE4D,PENK,PFKFB2,PGAM2,CCSER2,SLC25A23,PRKAR1B,ACSM5,ASIC4,SCG5,SLN,CXXC4,TMCC1,SOX15,TAC3,SLC19A3,CRTC1,THRA,TLL2,TRPS1,SLC17A7,PHTF2" Drug 988_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,ABHD6,C1QTNF3,ARNTL,PDE8B,SCAPER,SOCS6,ZFYVE9,SH2B1,TENM4,ATRNL1,ARMCX2,MFAP3L,SMG7,EXOG,EGR3,DMTN,ERCC2,F3,FAM198B,ANKFY1,GALC,MSL3,POLL,HNMT,ICA1,IL6ST,INPP1,JAK2,MPP2,ADAM22,SLC25A23,MAPK8,TMEM104,ATG16L1,RET,RGS10,SGK1,SYBU,ANKRD6,SLC15A2,CEP68,TTBK2,PLCB1,ATP11A,ADGRL3,FBXW11,TRIM2,RPGRIP1L,TGFBR3,CABIN1,ZFP37,REEP1,MPPE1,EPM2A" Drug 5811_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ACLY,ACTN1,GAS7,PPP4R4,ALDH7A1,KIF1A,NRP2,CFAP410,CACNA1A,CBFA2T2,ENTPD2,ARHGEF2,KCNAB3,ARHGAP33,LARGE1,CNOT8,CLTB,RAB26,AKAP7,ARMC8,SLC4A7,PDE4DIP,ARHGAP24,GIT2,MYEF2,C2CD2L,OPTN,EFNA3,NCALD,ETV1,TRMO,OGA,ERAP1,GLS,HPCA,NTRK2,SERPINI1,PPP5C,BEND5,KHDRBS2,SALL1,ZNF821,ITSN1,FUZ,AMBRA1,WDR37,SLC1A7,PEX26,KDM4D,TMCC1,TRIM2,TLR4,SSBP2,SEMA3B,EPM2A" Drug 7249_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MRTFA,BIN1,ANK3,APBB2,ARRB2,PTBP2,RUNX1T1,ARHGEF2,SRSF11,CHM,NRXN3,ZFYVE9,SDC3,RUSC2,SGSM2,DYRK1A,SIDT2,TENM1,PLEKHO1,DENND4A,ZNF549,ATP8A1,TESK2,ZNF589,KIAA1109,FGFR1,MSL3,HNMT,IFI16,INPP5B,MX1,NF1,NFYA,NOVA1,PAK3,PDE4D,STRN3,PPP2R5C,MAPK7,TMEM231,ROGDI,REV3L,RGS4,TTLL7,PPP1R9A,TMCC1,THSD1,SEPT8,SLC35G2,CABIN1,UBE3A,ZBTB14,ZNF189,NT5M,PDSS2" Drug 4476_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "TTYH1,ADCY2,PLA2G6,BCAS1,PPP4R4,CADM3,GYG2,CACNA1I,CACNA1D,MYOM2,CDO1,ADGRG1,CHRNB2,LHX2,DNAJB5,FAM149A,WHRN,TCEAL2,NCOR2,MICAL2,INTS1,MAML1,SPOCK2,SV2A,DTNA,DYRK1A,PLXNC1,NCALD,DLC1,ALDH1L1,GPR17,GRIK5,CACFD1,GRM7,AP4S1,ITGA7,KCNB1,MAN2A2,AFDN,MOBP,MYT1,FXYD7,PDE3B,PPP2R2B,CNTLN,DOCK10,SLC15A2,SCN3B,IZUMO4,PLCB1,TRIM2,PDIA2,OSBP2,VAV2,REEP1" Drug 6214_UP Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,AP2A2,AK2,PLA2G6,BIN1,APOC1,ALDH4A1,KSR1,CDK5R1,ZFYVE9,ARHGEF10,PDE4DIP,TBC1D5,KIAA0586,DAPK3,DCT,DLG3,DNM1,DTNA,MBNL2,EIF4G2,EIF5,FAM49B,GPR153,DISC1,USP19,GPR75,GNAL,NR3C1,BTN2A1,IFI16,INPP5B,KHK,NEK1,NF1,LRRN3,FAM120C,RALGDS,RNASEL,SGK1,ABLIM3,SLC1A2,BTBD7,SLC22A4,ZCCHC24,DOK5,SPTAN1,JMJD6,TEX15,EMSY,SCG2,MPPE1,PLSCR4,UBE3B,NUP214" Drug 4462_UP "ICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "DPF1,ADD2,ADRA1D,MRTFA,ANK1,PKP4,SLC2A11,CADM3,KIF1A,NRP2,BMP7,CHI3L2,CHN2,ZFYVE9,HAPLN1,PDE4DIP,RABGAP1L,EFNB3,TENM1,EN2,APC2,FAM49B,ERGIC3,OGA,GAB1,GAP43,RAPGEF4,AP4S1,FAM107A,ATXN2L,IL6ST,KCNF1,SAMD14,NPY,NPTX1,NPTX2,PALM,PCSK2,ENPP2,PFKFB2,MTRF1L,PPP2R2B,PTCH1,PTN,FAM120C,RNASE1,SEMA6D,SCN8A,NTNG1,CNKSR2,LIMS2,CXXC4,SYN2,TACR1,TPM3" Drug 3249_UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NDRG2,NME5,AMH,BIN1,CDC42BPA,APC,CACNA1I,CACNA2D1,CBFA2T2,ARHGAP33,DLGAP1,CHRNA4,TAOK2,DNAJB5,CNTN1,ENTPD4,ARHGEF4,EDRF1,SPOCK2,LYPD1,DUSP9,MBNL2,F3,GAB1,GLYR1,GNG4,TDRKH,STON1,KCNB1,MDM4,BCO1,NOS1,NUMA1,PFKFB2,PGAM2,CAMKV,PLCD1,MAPK7,SAMD9,PTN,RAD52,ZCWPW1,KLHDC8A,TCP11L1,PPM1E,ZNF365,SLC2A5,PKNOX2,CCDC88A,SLN,ATP10B,TROVE2,TBCEL,SZT2,PCDHA5" Drug 6521_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "KIDINS220,APC,ASCL1,ATM,AZGP1,CACNA1I,BAIAP3,CFAP410,CALB2,CDH2,CHRNA4,EPS15L1,NCOR2,SPOCK2,BRINP1,DCC,C2CD2L,FCF1,EFNB3,EGR3,AASS,SORBS3,IRAK4,FGR,GAD2,GFER,GJB1,GPER1,GRB10,RASSF8,JAK2,KCNC1,KCNN1,LAMA2,NEUROD1,NOVA2,NTRK3,PALM,MTRF1L,PPARA,MAPK8,WDR25,PNMA8A,SEMA6D,IL17RB,MRAS,SGK1,SMTN,SLC8A1,RAB3GAP1,SNAP25,TNS2,WIPF1,CLIP2,SLC30A3" Drug 7316_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY6,MTUS1,NME5,BCAR3,APP,PDXK,SCAPER,HIP1R,ARHGEF1,TBRG4,CLU,ARMC8,CPS1,HDAC4,CNIH3,LYPD1,RABGAP1L,EIF5,PLEKHO1,LRRC23,FGF13,CGREF1,TRAF3IP2,TMEM8B,SRCAP,PRRC2B,RASSF8,SYNPO,HNMT,SHISAL1,JAK2,MN1,TAGLN3,NF1,SLC11A2,ODF2,POLG,PTPRE,PTPRN2,RAD52,SUGCT,SUPT20H,PPP1R9A,AMBRA1,SMTN,SHANK2,SMARCC2,TNIK,COLGALT2,GSE1,AHCYL2,PARD3,EMSY,EVI5,AAAS" Drug 4677_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ARID1A,MTUS1,FAM131A,ATP1A3,SLC4A4,CACNA1G,SYNGR3,CRLF1,ABCG2,AKAP7,SLC4A8,ENTPD4,AATK,DAPK3,CTIF,BRINP1,SMG7,SPOCK3,ATN1,EDNRA,PLXNC1,ING4,EPHA5,CDKL3,FYB1,ZNF44,GLI2,MEF2C,AFF1,NF1,NPR2,OPCML,PDE4D,STRN3,CNNM2,SAMD9,WDR25,ZSCAN2,TMEM231,RGS10,MCMBP,FOXRED2,ZFP30,FRMPD1,SNCA,SOX15,LHPP,VAMP1,THRA,TK2,BHLHB9,WIPF1,NT5M,EVI5,NUP214" Drug 5959_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "PLA2G6,C1QTNF1,BIN1,AMT,EPB41L5,ALDH4A1,ADGRB2,MPDZ,CRLF1,RAB33A,IFFO1,CTNND2,ARHGAP32,DAPK3,MFAP3L,DPH1,DSCAM,PLXNC1,TNK2,PIPOX,ST3GAL6,FGF1,FGFR1,FYB1,GABRA2,MSL3,GPR19,GRIK5,ICA1,IL11RA,IL12A,KCNJ5,MDFI,NF1,PBX1,RETREG1,MAPK7,PTAFR,RAP1GAP,BEND5,GSTCD,ROM1,RASA3,SLC6A9,SIRT2,KDM4C,ARHGAP26,DDN,VAMP1,ASTN2,ZMYND8,TUBB1,NT5M,HPS4,MPPE1" Drug 5407_DN Ascorbic acid [50-81-7]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "AP2A2,BCAS1,APP,ARHGDIG,BRINP2,STX16,KIF1A,BMP7,SYNJ1,HAP1,ADGRG1,SOCS6,SLIT2,PLAA,HOMER3,SLC4A7,CREM,SH2B1,SIPA1L1,EDRF1,DSCAM,TOM1,MBNL2,HSD17B14,EZH1,F8,ACSL4,ATP2C1,GRIK5,CACFD1,ATXN2L,ELOVL5,HNMT,INPP5B,MIA2,KITLG,NFYA,NUMA1,RETREG1,PLXNB1,LRP12,PTHLH,ZDHHC14,ZNF821,SH3BP2,RBM34,LHPP,NXT2,INKA2,VAMP1,PLCB1,AHCYL2,AP4E1,EMSY,GDPD5" Drug 4592_UP Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "KIDINS220,ADGRF5,GAS7,ASTN1,NRP2,CACNA1I,RUNX1T1,ARHGEF2,CRLF1,CLCN4,CLTB,LY86,FAM149A,AKAP5,TCEAL2,PDE4DIP,PLPPR4,ATN1,EDNRB,ST3GAL6,SEMA4D,AFF2,DPYSL4,PDLIM5,GABRA2,ZNF44,TMEM8B,GPD2,GPER1,JAK2,KCND3,LSS,OPCML,PHKG1,RETREG1,SPATA6,PPARA,PRKAR1B,PTPRB,ZCWPW1,SCN2A,HKDC1,SLC1A7,SLC12A4,IZUMO4,NCDN,SYT11,TACR1,TNFRSF1B,TRO,WIPF1,ZNF74,ZNF225,MVB12B,NUP214" Drug 6751_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,ACTN2,PKP4,DDO,SEMA4G,CACNA1G,USP2,SYNGR3,CACNA2D2,ABCG2,AKAP5,SEC14L5,SPOCK2,SMG7,ARNT2,DUSP9,EDN3,EDNRB,PLXNC1,TENM1,DCTN2,SIGLEC8,GNAL,GNG3,TDRKH,GRIN1,ATXN2L,ELOVL5,IL6ST,ITGA7,KCND3,LAMA2,MX1,NCAM1,NNAT,NTRK3,CLDN11,P2RY1,PALM,GPR85,PMP2,PPP1R1A,MAPK8,BEND5,ZNF821,SLC11A1,NPAS3,ATP10B,PHLDB1,SEZ6L,TRO,HIRA,EPM2A,KAT6A,DPF3" Drug 1229_DN clozapine; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MTUS1,ALAD,APLP1,ARRB2,MARCH3,NCOA1,OSGIN2,CAMK2B,SOCS6,RAB28,BAG4,VCAN,SNPH,DTNA,OPTN,EGFR,DMTN,SPEG,ETV1,FECH,FGF1,OGA,GART,GLRB,CNTRL,MUM1,MAN1B1,IFI16,L1CAM,SLC11A2,OCRL,PDE4B,GRAMD1C,SYTL2,TMEM104,RIPOR1,TMEM231,RAD52,SEC61A2,MYH14,RPS6KA2,MAP6D1,HSPA4L,ASAP3,FUZ,PEX26,ZNF667,SNCA,SPATA7,TROVE2,THSD1,SYT11,SUPT5H,KAZN,AHCYL2" Drug 348_DN 2-propylpentanoic acid; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "KDM5D,ARID1A,NDRG2,BRAP,ANK3,KCNAB2,GAS7,SEMA4G,MARCH3,BMPR1B,NEURL1,CHGB,CHRNA4,HOMER3,IFFO1,SH2B1,AATK,EFNB3,SORBS3,ING4,STX2,ZMYND10,DCTN2,FOLR2,KHDRBS3,ADAM28,TXNL4A,RNFT2,ATXN2L,HMX1,KCNC1,FXYD6,NNAT,NOS1,NPTX1,POLG,MAPK7,MAPK8,SUSD4,GAL3ST4,RGS3,ARHGEF10L,KLHL11,TCP11L1,FOXRED2,ZHX3,PHLDB1,CRTC1,TF,THBS4,WIPF1,ZNF154,GDPD5,MPPE1,HRASLS" Drug 1784_UP Aconitine [302-27-2]; Up 200; 6.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NDRG2,C1QTNF3,CNTNAP1,ASPH,ALDH4A1,MYRF,RUNX1T1,CHN2,EPS15L1,IQCK,SPOCK2,CTIF,KIAA0753,DPH1,SORBS3,RASGRP2,VPS26C,POMT1,GAA,GABRA4,DISC1,ARFIP1,PCSK1N,BTN2A1,PADI2,TJAP1,KCNN1,NPPA,NTRK3,OGDH,OGG1,PDE4D,PTK2,RAD51D,RAD52,RGS12,C12orf49,ATXN2,FAM102A,SLC11A1,SLC12A2,SLC15A2,EMC1,THSD1,NCDN,SEPT8,CAMSAP2,PDLIM2,OBSL1,CBX5,TNS1,LAT2,HPS4,WIPF2,UBE3B" Drug 4836_UP Dydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY6,NME5,EPB41L5,CDK13,ATM,CFLAR,BAIAP3,HAP1,NEURL1,CDH8,QKI,SULT4A1,CNTFR,CSF1R,CNTNAP2,GREB1,NOS1AP,MAGI2,EDN1,EFNA3,DMTN,ETV1,FGFR1,FHL1,C1orf61,HBS1L,NR3C1,TJAP1,ITGA7,ITIH2,MAN2A2,MSR1,NDUFA5,SERPINI1,PACSIN1,GRAMD1C,MYH14,ZFP30,SMTN,CCDC88A,KDM4B,KIF21B,HECW1,AJAP1,EXOC7,KIAA1107,PSD3,PCDHA5,TPM1,LAT2,XRCC4,NT5M,GDPD5,NAV2,SLC17A7" Drug 4006_DN Oxamniquine [21738-42-1]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MRTFA,APBB2,APP,LGR5,ALDH7A1,ST3GAL5,CLU,RAB26,SH2B1,CREB5,C2CD2L,CDON,DTNA,MBNL2,IRAK4,MRNIP,COQ7,MTSS1L,ANKMY1,ST3GAL6,FOXG1,ZNF44,GAD1,GFER,C1QL1,TDRKH,LPAR4,GUCY1A2,SHISAL1,KPNA5,MN1,TAGLN3,ZNF862,NOVA1,EPN1,MAPK7,GRAMD1C,PRPH,KIRREL1,SH3BP2,SLC1A7,PEX26,SLC6A9,TSNAXIP1,THSD1,ARC,KIAA1107,TMEM121,TK2,MICAL1,WIPF1,REEP1,NT5M,KCNAB1,TIGD6" Drug 644_DN colchicine; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "RALGAPA1,KIDINS220,CDC42BPA,PPFIA3,ARHGDIG,NCOA1,SLC4A4,RIPK1,CFLAR,BAIAP3,HAP1,ARHGAP33,IFFO1,ECE2,HS3ST2,SGK2,OPTN,SRPK3,TUBD1,TUBB4A,GPR153,GLYR1,DIDO1,GRIK5,PRDM5,SCIN,KCNN1,STMN1,GIT1,NPR2,NTRK3,PPP3CA,PRKAR1B,MAPK3,MAPK10,RLBP1,RNASE1,FBXO11,RAB3GAP1,TSNAXIP1,ZC3H13,ZBTB43,SPART,ST5,DIP2A,PCDHGA1,SLC19A3,TMEM121,ZMAT3,TNS1,UBE3A,WIPF1,XRCC4,WNK1,FXR1" Drug 5968_UP H-7 dihydrochloride; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "AMT,DDX3Y,ATP1A3,ATP2A2,ARHGAP33,CLCN4,RAB26,COL9A2,MICAL2,PDE4DIP,CNTNAP2,RUSC2,SPOCK3,EGFR,ELAVL3,FOXG1,FLT1,EFCAB2,CINP,NSG1,DKK3,ZMYND11,GRM8,ELOVL5,IL6ST,ITIH2,KCNH2,KCNJ5,KCNMA1,NF1,PALM,PDGFRA,GPR85,EPN1,PTN,RGS10,SLC1A7,SLC6A8,SHANK2,SLN,SNAP25,SPTB,CDK19,DDN,ATP10B,MAPK8IP3,ASTN2,TEX15,SPX,VIPR2,WIPF1,MAP3K12,UBE3B,PHTF2,AAAS" Drug 4247_UP Piperine [94-62-2]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NME5,PKP4,CACNA1A,CACNG1,FOXN3,NRXN3,SUSD5,ERC2,RIMS3,DAPK3,SV2B,ECM2,EDN3,EPHB1,NCALD,ZNF391,ETV1,F5,PTK2B,KIAA1109,FGF1,PDLIM5,HBS1L,ERAP1,SYT17,NEU3,PCDH17,GPR22,CNTRL,IL6ST,LAMA2,SMAD1,MAP2,NCAM1,NRCAM,PDE3B,MTRF1L,PRKCB,PROX1,PTN,MARCH1,TMEM206,KCNIP1,SH3BP2,CPEB3,SLC1A2,SLC12A4,TNIK,SP4,ASTN2,TBCEL,HIRA,WIPF1,KCNAB1,KAT6A" Drug 5749_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,NDRG2,SEMA7A,CCDC181,SLC4A4,EIF4G3,SCAPER,GYG2,CACNA1I,LDLRAD4,CDH8,AKAP5,CREM,CSF1,RIMS3,HIPK3,ING4,ZNF549,KIAA1109,FGF1,TBR1,GABRG2,ZMYND11,SEPT9,GPM6A,GPM6B,GRIK2,PADI2,HNMT,KHK,KIT,LSS,MEF2C,AFF1,MN1,MYO7A,NF1,OPCML,PALM,PBX1,LRRN3,PTAFR,ZCWPW1,RGS10,RGS12,ZNF821,SLC11A1,ATP10B,COLGALT2,PHF24,CRTC1,HIF3A,CHST5,RPRM,SPHK2" Drug 7298_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "APBB2,CDK13,RGS9,SYNJ2,CACNA1A,USP2,MTMR7,PLEKHB1,DNAJB5,CREM,HAPLN1,CTNND2,HDAC9,MFAP3L,SPOCK3,HS3ST2,EDNRA,SIDT2,EGFR,AASS,MTSS1L,EPHA5,DENND4A,REEP2,GLRB,PRUNE2,LPAR4,GRM8,TJAP1,KCND3,KIF5C,MAPT,ODF2,PRPH,PEX5,RGS12,TTLL7,PAQR6,ST6GAL1,ARHGEF40,SLC9A5,SOX2,KIF21B,TSPYL2,VAMP1,ASTN2,RPGRIP1L,PHF24,NSD1,TEX15,TIAM1,TNS1,WIPF1,TFIP11,KCNAB1" Drug 6773_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "RALGAPA1,ARID1A,ADRA1B,ADRB2,SEMA4G,ASPH,BCL2L2,CFLAR,CLGN,CHRNB2,EPS15L1,TPP1,CNTN1,RGS6,DCAF4,RIMS3,GSDME,PARD6A,TRAPPC9,DSCAM,MRNIP,MTSS1L,TUBB4A,DLC1,FGFR1,B3GAT1,ALDH1L1,SRCAP,GLYR1,IRAK3,IL6R,ITGAM,KCNB1,KCNJ5,MBD1,MDFI,NUMA1,CLDN11,PIK3CD,LRP12,CEP41,RGS10,TCP11L1,FRMPD1,FAM214B,SNCA,DOK5,SPTB,RGL1,PLCB1,ASTN2,TRIM2,CRTC1,TK2,SSPN" Drug 2808_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADRA1D,PLA2G6,LTBP4,GAS7,SLC4A4,BMP7,BAIAP3,SLIT2,EPS15L1,AKAP7,WHRN,RIMS2,DCAF4,NOS1AP,RUSC2,SHANK1,EIF4G2,ZNF589,FGF12,CAMSAP1,C1orf61,PRUNE2,GPER1,SPACA9,ADAMTS13,ICA1,KCNQ3,GIT1,NEUROD1,CLDN11,PFKFB2,CAMKV,PLCD1,PLXNB1,PURG,NECAB2,SNRK,RAB3IL1,RASGRF1,ZDHHC14,RFX2,ASIC4,DZIP1,SLC2A5,PKNOX2,ARHGEF40,SLN,SNCA,KDM4B,SOX10,SPTAN1,PSD3,CABIN1,ITM2C,MVB12B" Drug 264_DN MK-886; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,NDRG2,LTBP4,ANK1,CDK10,ARRB2,ASCL1,CADM3,CAMK2A,CDH2,ARHGAP33,DLGAP1,B4GALT6,CREM,CRHBP,OSBPL3,SIPA1L1,ECE2,DAPK1,GIT2,FEM1B,SPEG,CDKL3,FGR,GLS,PRRC2B,LILRA2,AP4S1,HMX1,STMN1,MBD1,BCO1,C19orf57,HYDIN,CNNM2,MTMR10,ZCWPW1,TRIM68,KLHDC8A,TCP11L1,ASIC4,FERMT1,ST6GAL1,KBTBD4,HECW1,KDM4C,PHLDB1,ZFR2,ATP11A,CRTC1,TF,CDH22,RIMBP2,SEZ6L,ZBTB16" Drug 7338_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,ALCAM,CDC42BPA,ANK3,CDK13,CFLAR,LRIG1,CTH,DLG3,MED12,ATN1,SIDT2,EFNB3,SORBS3,COQ7,STX2,F3,KAT8,SEMA4D,AHDC1,COPS8,GLYR1,MSL3,GPD2,RNFT2,INPP5B,KCNF1,KCNH2,MMP16,MPP2,NEK1,OXTR,PRKAR1B,MAPK8,ELOVL2,PEX5,RAB3A,GSTCD,NEK11,ITSN1,EPN2,BTBD7,EMC1,ATP11A,KIAA0930,SZT2,CADM1,VIPR2,MAP3K12,EMSY,DNALI1,HPS4,WIPF2,ST7,SMIM8" Drug 6285_UP Amoxicillin [26787-78-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,MRTFA,DOC2A,PPP4R4,MAGI1,CACNA2D2,SULT4A1,RAB26,COL9A3,CPS1,CRMP1,ABCG1,AATK,CSF1,SUSD5,DZIP3,CTNND2,RUSC2,DSCAM,ELAVL3,EPB41L1,COQ7,RRAGB,CACNG2,ST3GAL6,AFF2,GALC,TMEM8B,ZNF276,GNAL,GNG3,IFI16,KCNB1,KCNN1,MX1,NOVA1,SAMD9,PTPRE,KHDRBS2,RGS4,MYH14,RAB3GAP1,CCDC88A,SNCA,SCN3B,ATP10B,NCDN,PHLDB1,MLC1,PCDHA5,TK2,VGF,LMF1,WIPF1,ZBTB14" Drug 5459_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "BIN1,ANK1,APAF1,APBA2,MPDZ,BAIAP3,HIP1R,CHRNB2,EPS15L1,PLAA,KIAA1549L,CLCN4,ATN1,ST8SIA3,EDNRA,HIPK3,EFNB3,EGFR,ELN,DLC1,ATP8A1,ERAP1,GLS,GNAO1,GNG3,PRUNE2,ICA1,KCNJ5,KCNQ3,MAOB,MEF2C,MSR1,PDE1C,MTRF1L,MBOAT7,PTPRB,RAD52,KCNIP1,FAM214B,KDM4B,PDZD2,TNIK,DOK5,ATP10B,VAMP1,ARC,DOCK9,RALYL,DAAM2,AMOT,PLPPR2,WIPF1,SLC13A3,XRCC4,HPS4" Drug 5927_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,ADRA1D,PLA2G6,CDC42BPA,APAF1,PLA2G4C,KALRN,PLAA,TPP1,ARHGEF6,AKAP7,SPOCK2,MFAP3L,RUSC2,DTNA,EFNB3,TUBB4A,FGF13,SCARA3,GAD1,GPD1,SPACA9,AP4S1,ITGA7,MAP4,AFDN,NEK1,NNAT,PDE4D,SERPINE2,PLEC,POU3F4,PTPRH,RNASEL,FBXW7,EMID1,DGLUCY,SELL,ZNF821,FNDC3A,SLC2A5,FAM214B,PKNOX2,ZSWIM8,TROVE2,AJAP1,ARC,EXOC7,PCDHGA1,DNAH7,AP4E1,THRA,HEY2,TRIO,SLC30A3" Drug 6311_DN Clebopride maleate [84370-95-6]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "AMT,CDC42BPA,APC,C5,CA12,SEPT7,FOXN3,ARMC8,NRG2,CNTNAP2,DPH1,RCAN1,OPTN,ING4,ERCC2,CDKL3,BAIAP2,CINP,OGA,FYN,B4GALNT1,ERAP1,DISC1,GPR37,BACH2,IL11RA,MAPT,MEIS1,TAGLN3,ZNF862,NDUFA5,NFYA,SLC11A2,PLCD1,FSD1,PTPA,PPP5C,PTHLH,PEX5,ZDHHC14,GAL3ST4,RPS6KA2,SAFB,ASAP3,NLGN1,IFT122,WDTC1,BEX1,NXT2,SEPT8,GSE1,TCF4,SYNE1,ZNF34,URM1" Drug 6963_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ABAT,CDC42BPA,PPFIA1,PKP4,DGKD,ST3GAL5,MAP7,FOXN3,CREM,DCAF8,TBC1D5,GIT2,DCTN1,ZBTB24,COPS7A,MED24,SMG7,RABGAP1L,TRAPPC9,RCAN1,FGFR1,FAM49B,TXNL4A,MSL3,PRRC2B,HNMT,HSF2,RBPJ,KIF2A,NASP,NCAM2,NFYA,NUCB1,SLC25A23,RC3H2,FA2H,ROBO1,CCDC25,TRAPPC13,SFPQ,ZFP30,KIF16B,FUZ,RAB3GAP1,ZSWIM8,ITPRID2,SS18,ARHGEF9,COBL,PSD3,ARHGEF12,RBFOX2,ZNF189,MAP3K12,ACTR3B" Drug 7172_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "APOC1,CDK10,CADM3,CFLAR,SYNJ2,SCAPER,GYG2,CAMK2B,SCARB1,QKI,SLC4A8,BAG4,EDRF1,DBN1,PARD6A,RCAN1,OPTN,MBNL2,DENND4A,DLC1,EFCAB2,DPYSL4,POLL,GRB10,CACFD1,NR3C1,KLF12,LMO2,VWA5A,MEIS2,MPP2,NNAT,PDE4A,MAPK8,SNRK,ELOVL2,RGS12,TCP11L1,FUZ,PPP4R3A,SLC6A9,ZKSCAN3,ZCCHC24,PHLDB1,VPS13A,SYT5,PCDHGA10,THRA,TPM1,NPL,TRIO,ZMYND8,FLRT2,NAV2,MPPE1" Drug 6228_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADRA1D,PLA2G6,SEMA6A,BIN1,APOC1,BCAS1,PPFIA3,PLA2G4C,BTRC,CDH8,TPP1,CNTFR,IQCK,PDE4DIP,DAPK3,TMCC2,SORBS3,ECSIT,KIAA1109,GPR153,GLYR1,GLS,TJAP1,INPP5B,KHK,KIF2A,MATK,KITLG,MSI1,MSR1,NOVA2,NPR2,PPP5C,SAMD9,WDR25,ELOVL2,FAM184A,KHDRBS2,RGS12,ZFP30,ASAP3,SLC11A1,SLC15A2,IZUMO4,HECW1,DBNDD2,ZBTB43,THSD1,PHLDB1,EXOC7,ZNF34,TRPM2,UBTF,SEMA3B,MPPE1" Drug 2953_UP Lymecycline [992-21-2]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "MTUS1,ALK,APOC1,ZFYVE9,PLAA,SULT4A1,AKAP6,ABCG1,CRYM,CNTNAP2,ZNF337,TM9SF4,SMG7,EXOG,DRP2,ATN1,CELSR3,TNK2,LRRC23,RASGRP2,ZNF549,ETV1,F5,PTK2B,ST3GAL6,GPR153,GATM,KCNMB4,GNG3,PADI2,HMGB1,HNMT,KHK,AFDN,MYO7A,NOVA1,OXTR,PLCD1,PTPA,PTAFR,RAB3IL1,SEC61A2,IL17RB,MRAS,FAM102A,ASAP3,WDTC1,ST5,EXOC7,PDLIM2,WWC1,ZNF34,RBFOX2,CA10,KCNAB1" Drug 6495_DN Methylatropine nitrate [52-88-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "BRAP,MRTFA,DOC2A,FAM131A,APOC1,BCAS1,CDK10,CFLAR,SCAPER,OSGIN2,CDH10,B4GALT6,CLU,PDE4DIP,DZIP3,SDC3,GIT2,ZNF804A,C2CD2L,PARD6A,RABGAP1L,EGFR,STX2,EZH1,SEPT9,INPP5K,MALT1,KCNJ3,KIF2A,VWA5A,MIA2,MPP2,NEK1,OGG1,PRODH,FAM120C,RIPOR1,BSDC1,SAFB,ZNF821,URGCP,SIRT2,SCMH1,CAMTA2,MAPK8IP3,STX1A,NSFL1C,COBL,EXOC7,KIAA0930,CHST8,KCTD2,HPS4,EPM2A,SSPN" Drug 2567_UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "NDRG2,AP2A2,MTUS1,PKP4,ZSCAN18,CADM3,HIP1R,NEURL1,ZFYVE9,CRY2,SLITRK5,DZIP3,DNAJC6,ATN1,EFNA3,EFNB3,PTK2B,SEC23B,GALC,GAP43,TMEM8B,ZNF276,GPD2,STON1,CACFD1,GSN,KCNN1,LIG4,SAMD14,NAP1L2,PDE3B,PDE4B,PFKFB2,PLCD1,STRN3,MAPK8,CNNM2,PTPRN2,C12orf49,TMEM206,SLC11A1,SS18,ARHGEF9,RPGRIP1L,PSD3,AHCYL2,ICAM5,PIK3R5,ZMYND8,TUBB1,FLRT1,LMF1,CLIP2,SLC26A10,PHTF2" Drug 6368_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,AMT,KCNAB2,BMPR1B,CACNA1I,CFAP410,CACNB2,HAP1,CNR1,CHD5,MFAP3L,HIPK3,EGFR,ING4,APC2,ETV1,CAMSAP1,FOXG1,OGA,ZMYND11,SRCAP,C1QL1,PTGDR2,INPP5B,KCNA2,KCNN1,VWA5A,MAOB,MMP16,ADAM22,DDR2,OPRL1,PDE2A,PMP2,STRN3,PACSIN1,PPARA,MINDY2,SEC61A2,KCNIP1,STUM,RIMS1,SCN3B,WDTC1,DOK5,SSTR2,SS18,TRO,HIRA,UBE3A,WIPF1,STMN4,SCG2,MPPE1,KAT6A" Drug 2745_UP Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "OSBPL1A,DOC2A,APC,APP,MARK4,ZBTB10,ST3GAL5,GYG2,BTRC,CAMK2G,CLGN,RCBTB2,HOMER3,PICK1,BAG4,CREM,SH2B1,SNCAIP,KBTBD11,SLC12A6,DYRK1A,EFNA3,LRRC23,TESK2,DPYSL4,RUNDC3A,RND1,GNAS,GNG3,GPER1,GPR37,BRINP3,MAP4,NF1,PIK3CD,PPARA,PPP5C,CEP41,MAPK8,MAPK10,GRAMD1C,PTHLH,RIC8B,EMID1,ATXN1,PPP1R9A,PREX2,WDTC1,KAZN,CRTC1,TNS1,PDIA2,VGF,SF1,KAT6A" Drug 4204_UP Epitiostanol [2363-58-8]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ACTN2,NDRG2,AP2A2,DOC2A,KCNAB2,APC,EPB41L5,GAS7,RASL11B,MAP7,SCARB1,CDC42,LARGE1,SULT4A1,AKAP5,IFFO1,HAPLN1,PHF14,DBT,HIPK3,ETV1,KIAA1109,FLT1,AFF2,PDLIM5,ERAP1,GATM,MSTN,LYVE1,TXNL4A,TDRKH,STON1,CNTRL,KCNJ3,MX1,MYO7A,NF1,NTRK2,PDGFRA,PTHLH,ACSS3,SUSD4,RPRD1A,SEMA6D,ZFP30,ST6GAL1,PREX2,SLC14A1,SMARCD3,CAND2,MCF2L,PCDHA5,SEZ6L,TPM1,SLC17A7" Drug 6885_DN AH23848 hemicalcium salt hydrate; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASPHD1,SEMA7A,APBB2,APP,CDK5R1,CFAP410,CACNB2,CBFA2T2,ABCG1,CTNND2,FAM131B,RIPOR2,ZFYVE16,DAPK3,MFAP3L,SMG7,SIDT2,AASS,ING4,STX2,FGF1,FGFR1,B4GALNT1,TMEM8B,C1QL1,COPS8,GLI2,SHISAL1,TJAP1,KCNJ5,NFYA,NOS1,PC,PLEC,C19orf57,PRKAR1B,MAPK7,CNNM2,RAD52,RPS6KA2,RXRA,SBF1,ZNF821,IFT122,SNCA,TROVE2,SYN2,KIAA1107,TNS1,SSBP2,VGF,XRCC4,REEP1,SLC30A4,MAP3K12" Drug 5516_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ASIC1,NLGN4X,PLA2G6,SEMA7A,LGR5,CDK13,HIP1R,INA,NEURL1,LY86,SNCAIP,DCAF4,KBTBD11,SLC12A6,MTSS1L,NCALD,F5,DLC1,FGFR1,FHL1,TPK1,DLL3,INPP5K,GLYR1,GPM6B,TDRKH,CACFD1,IL6ST,IPO5,LIG4,MYT1,PCSK5,PDGFRA,NLE1,PLXNB1,STRN3,PACSIN1,POLG,RALGDS,GTDC1,TCP11L1,MRAS,SLC2A5,ARHGEF40,ZKSCAN3,SORCS3,HECW1,ERC1,STX1A,PLCB1,ROBO3,KCTD2,CABIN1,ZMYND8,HPS4" Drug 3239_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.24E-05 6.08E-01 1.94E-04 2.21E-03 55 199 "ADCY2,APAF1,APC,ATP2B2,SYNJ2,LDLRAD4,CA8,NEURL1,TPP1,FAM189A2,DNAJB5,ABI3BP,SIPA1L1,CYBB,RIMS3,NTM,HIPK3,F5,FAM198B,DLC1,FGFR1,SCARA3,SORBS1,HBS1L,GPER1,GRM3,GRM7,GSN,KCNJ5,MAN2A2,NELL2,NPPA,CDK14,MAPK10,SNRK,ZSCAN2,RPS6KA2,CLIP1,PREX2,LIMS2,KANSL3,SLC22A4,SNCA,KIF13A,KIF21B,IZUMO4,JMJD6,DOCK9,PSD3,ARHGEF12,AP4E1,CLIP2,NT5M,EPM2A,FAM13C" Drug CID005329102 sunitinib Stitch 1.25E-05 6.12E-01 1.95E-04 2.22E-03 40 130 "CLK4,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CSF1,CSF1R,DAPK3,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,FER,FGFR1,FGFR3,FGR,FLT1,CAMKK2,FYN,GFRA2,MAP4K5,MYLK2,JAK1,JAK2,KIT,NELL1,PDGFRA,PHKG1,PTK2,RET,BAALC,RPS6KA2,SLC12A2,TNIK,ALG1,TEK,EPM2A,CAMK1G" Drug ctd:C054133 casticin CTD 1.26E-05 6.16E-01 1.96E-04 2.23E-03 66 252 "AXIN2,SPARCL1,APAF1,ARNTL,HCN2,BID,CALM1,CDC42,QKI,CRHBP,FEZ1,RAB39B,DYRK1A,ABCC5,EGFR,EIF5,IRAK4,OLIG2,GPHN,WAC,ATP8A1,SYNCRIP,FOXO3,NRG3,DKK3,PPARGC1A,KIRREL3,RAPGEF4,NKD1,IL12A,NME9,KCNH2,SMAD1,MARK3,MBP,SYT9,MEST,MYO7A,P2RX7,PAK3,GPR85,PMP22,EPB41L4B,CRLS1,PTK2,PTPRD,ZSCAN2,ZFHX4,TRA2B,FBXO11,ST3GAL3,SLC6A9,RCOR3,LIMCH1,NPAS3,TAB2,TCF7,PCDHA1,THRA,TLR4,ZNF384,METTL3,TRIO,CADM1,VLDLR,ZNF711" Drug 5908_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.27E-05 6.21E-01 1.98E-04 2.25E-03 52 185 "DPF1,ABAT,ADRB2,ARNTL,ALDH7A1,NOL4,ATP6V0A1,ST3GAL5,HIP1R,USP2,NRXN3,CLU,ABCG1,PDE4DIP,CTH,KIAA0513,C2CD2L,PLPPR4,SRGAP3,EFNA3,MRNIP,RGS17,TAOK3,TESK2,BAIAP2,SORBS1,PDLIM5,FYN,CYP46A1,PCDH17,C1QL1,RND1,GLS,ACOT7,DIPK1A,KIF5C,MAPT,ENPP2,SERPINI1,PIK3CD,RETREG1,RGS4,FBXW7,SH3GL2,SH3GL3,ASAP3,ELOVL4,RGL1,SYT11,SYT1,SSBP2,DNAJC12" Drug 7209_UP Harmine hydrochloride [343-27-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-05 6.52E-01 2.08E-04 2.36E-03 53 190 "CLK4,ARID1A,ADORA2A,AK2,C1QTNF3,APBB2,CADM3,N4BP2L1,CACNA1A,SRSF11,FOXN3,CREM,GREB1,RASGRP2,EPHB1,CDKL3,FYB1,HBS1L,SESN1,GLYR1,GLS,LPAR4,GRK4,GRM8,AP4S1,PTGDR2,LIG4,MGAT3,MSR1,MYCN,ZNF862,PALM,ENPP2,NLE1,PLP1,SMIM7,STRN3,RAB3IL1,RAD52,GSTCD,RPS20,PAQR6,PPP4R3A,BTBD7,ZNF415,DOK5,SAMSN1,PHLDB1,ARHGEF9,TEX15,ZMAT3,MVB12B,TIGD6" Drug 4144_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-05 6.52E-01 2.08E-04 2.36E-03 53 190 "NME5,AK2,AMH,CDC14B,BRINP2,SLC2A11,CFLAR,SYNJ2,CDC42,ADGRG1,CHRNB2,NCOR2,CSF1,CTIF,BRINP1,EDNRA,FABP7,FGFR1,AGAP2,DCTN2,NSG1,TMEM8B,GATM,SRCAP,GFAP,GFER,GPM6A,ATXN2L,HTR2A,KIF5A,CNOT4,PCSK2,GPR85,PIK3CD,RETREG1,POU3F2,MAPK7,GDPD2,PTPRB,ENOX1,TTLL7,GSTCD,RYR1,PKNOX2,HECW1,UNC5B,JMJD6,SLC35G2,R3HDM1,TNS1,AMOT,MKRN3,SLC30A3" Drug CID000000867 malonate Stitch 1.34E-05 6.57E-01 2.09E-04 2.38E-03 57 209 "ANK3,GPAM,DDO,APP,C5,TBRG4,PLEKHB1,CHRNA4,CHRNB2,SLC22A6,NSL1,CS,DCT,SLC29A4,SGK2,AASS,FCGRT,SEMA4D,ADAM28,GPM6B,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NEGR1,IDH3A,KCNH1,KCNH2,KCNK3,MAP4,MAT2A,OGDH,CNTN3,PC,FXYD1,PRODH,PTPRB,PTPRD,SCN2A,SCN2B,SCN3A,SLC1A2,SLC1A3,SLC1A6,SLC6A7,SLC11A1,WDTC1,SGK3,SLC13A3" Drug CID000005494 TMB-8 Stitch 1.34E-05 6.58E-01 2.10E-04 2.38E-03 50 176 "ADCY2,ADCY5,ADCY6,ADCY8,AGT,PLA2G6,ATP2A2,ATP2B1,ATP2B2,ATP2B3,AZGP1,CACNA1I,CACNA1G,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,KRIT1,CD38,CHRM1,TJP2,CSF3R,DLG3,PDCD6IP,EDN1,EDN3,ABI2,PTK2B,ATP2C1,MSTN,MCHR1,STMN2,MAP4K5,SCRT2,ITGAV,MITF,NODAL,NOS1,ABCB1,PRKCB,PRKCG,MAPK3,RYR1,RYR3,SYT1,LEFTY2,TRH,PLPPR5,PLD4" Drug CID000164531 H-8105 Stitch 1.35E-05 6.59E-01 2.10E-04 2.39E-03 72 282 "ACHE,KDM5D,ADCY5,ADCY6,ADCY8,ADRA1B,ADRB2,APAF1,APC,ASCL1,CA4,CACNA2D1,CALB1,CALB2,AIFM1,CHGA,CHRM1,CHRNA4,BOC,SLC29A4,DRD1,STX2,ZMYND10,ACTL6B,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,INPP5K,GFAP,BRD8,LOXL3,GRIK1,NR3C1,GRM2,CIT,HRH3,TNFAIP8L3,HTR5A,IGF1,JAK1,KCNJ3,KCNJ4,KCNJ5,NCAM2,NPY,NUCB1,NUCB2,PAH,PENK,MBOAT7,PRKCB,PRKCG,MAPK3,FEZF2,RIT2,GLDN,SOX10,SST,JMJD6,PLCB1,TAC1,TAC3,TACR1,TF,ACTR6,TRH,SLC17A7" Drug 5388_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "APLP1,APOC1,ARHGDIG,ATP6V0A1,CA12,ADGRG1,PLEKHB1,B4GALT6,TAOK2,SH2B1,PDE4DIP,DZIP3,DBN1,HP1BP3,LYPD1,SMG7,DTNA,CNNM1,SIDT2,ZNF589,IQCG,TPK1,GCNT2,RUNDC3A,GLYR1,GPR19,GPER1,ATXN2L,KCNH2,MBD1,TM6SF1,NF1,RETREG1,PTHLH,FAM120C,ZNF821,SH3BP2,SLC1A7,ST5,INKA2,ATP11A,KAZN,SEMA4A,PSD3,TGFBR3,CABIN1,HIRA,PLPPR2,VAV2,KCNK12,ZNF24,EMSY,HPS4,KAT6A" Drug 6558_UP 5194442; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "DOC2A,BIN1,AMT,CFLAR,BMP7,GYG2,CFAP410,CA4,CCNT1,CHRNA4,TAOK2,LHX2,NMT2,SH2B1,CSF1R,SDC3,CTH,DBT,CNNM1,COQ7,KAT8,AGAP2,ATP2C1,GPR153,GFER,GLS,GNG4,GRB10,ATXN2L,TJAP1,MXI1,NFYA,PCDH9,PDE3B,LRP12,RALGDS,RGS12,ROM1,WLS,KCNIP1,ASAP3,SPTAN1,ANKRD12,EXOC7,CRTC1,CHST8,TK2,RUNDC3B,RPRM,FAM155A,KLC2,ZBTB14,ZNF189,EMSY" Drug 3806_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASPHD1,ARID1A,AP2A2,MRTFA,SEMA7A,PKP4,PPP4R4,RASL11B,ATP1A3,BMP7,ABI3BP,CRMP1,RIMS2,SMG7,ING4,FGF1,FYB1,GNG4,GPD2,GPR17,ATXN2L,ITIH2,KIF5C,KIT,MAPT,LYRM9,NLE1,EPN1,CDIP1,STRN3,TNPO2,MAPK7,PRPH,CNNM2,PTPRB,ACSS3,RAD52,MYH14,PAQR6,SUPT20H,RASA3,ASAP3,ST6GAL1,NLGN1,ZNF334,OGDHL,SNCA,DOK5,ZHX3,UNC5B,SPTAN1,LHPP,ATP11A,IQCE" Drug 2333_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ADGRF5,BEGAIN,DOC2A,AMT,LGR5,CDK13,MARK4,BACH1,CFLAR,SYNJ2,C5,ARHGEF1,PDE4DIP,CTNND2,ZFYVE16,SPOCK2,TRAPPC9,RCAN1,ABCC9,EIF4G2,COQ7,ERBB2,PRKAG2,FHL1,ANKFY1,GAB1,ERAP1,SIGLEC8,GRB10,ITGAM,VWA5A,MAP4,MBP,AFF1,SMOX,PLP1,RC3H2,KLK6,CNNM2,GDPD2,PTCH1,RIPOR1,RGS3,RXRA,SEC14L1,BCAN,BTBD7,SLCO1A2,DOK5,PBLD,KAZN,CHST8,KAT6B,KCNK12" Drug 4466_DN Rapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ARID1A,AMPD3,CDK13,ATP6V0A1,ADAM23,BMPR1B,RCBTB2,LHX2,NRXN3,TCEAL2,NRG2,ARMCX2,SPOCK3,DMPK,DTNA,ECM2,PLXNC1,ANKMY1,ZNF276,CRCP,ICA1,KIT,VWA5A,NF1,NFIX,PFKFB4,PIK3R1,CCSER2,PLCB2,PRKAR1B,GON4L,PTX3,RAB3IL1,TMEM206,ZNF821,BCAN,SLC1A3,KDM4C,SPTB,DDN,LHPP,VAMP1,KAZN,EHBP1,RPGRIP1L,CHST8,TNS1,RUNDC3B,ZNF711,ZNF24,TRIM9,PRDM2,EPM2A,PHTF2" Drug 7318_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "APC,GAS7,BAIAP3,CACNA2D2,NMT2,CSF1,PDE4DIP,CTNND2,EDRF1,HDAC9,DNAJC6,EIF4G2,EN2,COQ7,DLC1,KIAA1109,FGF1,C1orf61,FLT1,GABRA2,GAD1,ZNF276,DIDO1,SPACA9,GRIK5,DIPK1A,INPP5B,LYRM9,MYO6,PDE1C,ENPP2,CCSER2,PURG,MAPK3,PROX1,RFX2,KCTD17,NEK11,SH3BP2,AMBRA1,FAM214B,SLC11A1,PDZD2,ZHX3,LHPP,THSD1,SS18,MAPK8IP3,KAZN,DOCK9,CABIN1,XRCC4,SPHK2,DPF3" Drug 4300_UP Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ADORA2A,PKP4,PDE8B,N4BP2L1,INA,CHI3L2,RIMS2,RIMS3,DTNA,EDN1,MRNIP,F5,DLC1,KAT8,ZNF589,TRMO,TBR1,RUNDC3A,GNG4,MCHR1,GRM1,FAM107A,HTR2A,IL6ST,KHK,KITLG,AFF1,GIT1,ADAM22,MSR1,NEUROD2,PCBP3,PDE3B,GPR85,PFKFB4,PRPH,VPS13C,RET,RGR,RGS12,FOXRED2,ASIC4,DZIP1,SLC1A2,SLC11A1,ZNF667,MCF2L2,VAMP1,TACR1,TCF4,CADM1,UBE3A,LAT2,PRDM2" Drug 2702_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "SYT13,AMPH,ASPH,ALDH4A1,AZGP1,RGS11,CACNB4,CAMK2A,CDH10,GPR37L1,TAOK2,KIAA1549L,AKAP6,COL9A3,CREM,SIPA1L1,PDE4DIP,USP6NL,DGKG,HIPK3,AASS,TNK2,FAM198B,SORBS1,PDLIM5,GABRA1,GABRA2,GPR19,STON1,KLF12,HNMT,IL12A,KCND3,MOBP,MYO7A,MYT1,NTRK3,PDGFRA,PHKG1,POLG,SUGCT,ZNF821,ABLIM3,EPN2,SLC11A1,SOX10,ATP10B,ARC,TACR1,TRIM2,PSD3,SEZ6L,PHTF2,JPH3" Drug 3737_DN Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ALK,CDC14B,ADGRB2,C5,SYNGR3,ARHGAP22,HOMER3,CNTN1,IFFO1,NCOR2,ABCG1,AATK,SDC3,CTNND2,MAML1,CNIH3,SMG7,DTNA,APH1A,ELAVL3,FGF1,FGFR1,C1orf61,CINP,PDLIM5,CGREF1,FERMT2,HSD17B1,KCNJ5,VWA5A,MOBP,PDE3B,PDE4B,PDPK1,POLG,CEP41,PID1,KIRREL1,RPS6KA2,ZNF821,ASAP3,DZIP1,BTBD7,WDTC1,SPTAN1,MCF2L,SYNE1,TPM2,HIRA,CADM1,RPRM,PLPPR2,SEMA3B,DPF3" Drug 4182_UP Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "APOC1,AQP6,ATP1A2,SLC2A11,CACNA1I,BRSK2,CBFA2T2,ADGRG1,WHRN,CSF1,CNTNAP2,HDAC9,DAPK1,DCT,DMD,DMPK,FAM13A,CEND1,DCTN2,DLL3,OGA,ARPP21,GCNT2,SRCAP,PCDH17,SOX21,HLF,SCRG1,KCNMA1,CD200,CNOT4,DCHS2,SNRK,GAL3ST4,SALL1,SCN8A,AMBRA1,PKNOX2,ZNF334,LIMCH1,LMO3,MAPK8IP3,ATP11A,SZT2,SLC35G2,TEK,SLC44A1,TNS1,TRH,OSBP2,VAV2,WIPF1,MVB12B,ADAMTSL3" Drug 5676_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "RALGAPA1,ADD2,BEGAIN,SLC4A4,MTMR3,GYG2,CACNG1,CALB2,CD86,CLCN4,CRYM,CSF1,SPOCK3,DTNA,HIPK3,F5,KIAA1109,KHDRBS3,GABRA2,GAD1,ERAP1,DISC1,ATP8A2,SRCAP,GNG3,GPM6A,LPAR4,CACFD1,HLF,KCND3,KCNH2,KPNA5,MGAT3,MYL3,NCF2,NPTX1,TMOD2,PGAM2,NLE1,PLCD1,EPN1,GRAMD1C,RAB3A,SBF1,SCN3A,SELL,ZNF821,BCAN,EPN2,SOX2,EPB41L3,AJAP1,TNS1,TRIM9" Drug 3671_DN Mebendazole [31431-39-7]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "APBB2,SEMA4G,CDK13,SCAPER,SCARB1,RAB28,KIAA1549L,CNTFR,SH2B1,TENM4,DZIP3,GPRASP1,DCAF8,DLG3,ATN1,MBNL2,MRNIP,PLEKHO1,VPS26C,RRAGB,TUBB4A,SCML2,BAIAP2,DISC1,SESN1,GLYR1,MAP4K5,MUM1,KHK,PDGFRA,SLC25A23,RAB3A,FAM184A,ZNF821,ASAP3,SLC1A7,CCDC88A,RCOR3,IFT122,SPATA7,LHPP,SAMSN1,SS18,PHLDB1,TCF4,TCF7L2,PSD3,AHCYL2,TNS1,RBFOX2,WNT7A,ZNF74,WNK1,SMIM8" Drug 5450_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "NDRG2,MRTFA,APBB2,PDE8B,MARK4,SYNJ2,SCAPER,MTMR3,BAIAP3,CBFA2T2,ARHGAP33,ARHGEF6,SH2B1,NCOR1,SDC3,PPP6R2,NOS1AP,DAPK3,SMG7,DNM2,EFNA3,MBNL2,EML1,IQCG,MPP6,TRAF3IP2,GLYR1,MSL3,MUM1,ELOVL5,KCNJ3,KPNA5,NF1,CNOT4,SLC11A2,SERPINE2,SLC25A23,PLXNB1,LRP12,TNPO2,PPP5C,PTCH1,SLC1A7,SHANK2,BTBD7,SLC20A2,INKA2,MAPK8IP3,PLCB1,EXOC7,ZKSCAN5,WNK1,GDPD5,SEMA3B" Drug 5305_UP Cisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASPHD1,AP2A2,CDK13,ASPH,ATM,KIF1A,BMP7,C5,BTRC,CFAP410,HIP1R,SYNGR3,RAB26,CSNK1E,PDE4DIP,GREB1,GIT2,PARD6A,MED12,DTNA,OPTN,FECH,BAIAP2,FHL1,PRELID3A,GAD2,GAP43,POLL,SLC2A6,KCNN1,MAP4,NF1,OGG1,SLC25A23,RAD52,ZCWPW1,TCP11L1,KCNIP1,ATXN1,ITSN1,SYBU,EPN2,FAM214B,BTBD7,KIF21B,ARHGAP26,EXOC7,TCF7,TCF7L2,ATP13A2,TMEM121,TMOD1,KLC2,HPS4" Drug 6821_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ABHD6,NDRG2,ADCY6,CDC42BPA,BCAS1,MARK4,CACNB2,TAOK2,ARMC8,CTH,ARHGAP32,EXOG,SLC12A6,EDNRA,EFNA3,TNK2,SCML2,SEMA4D,SMC2,MALT1,GLYR1,GNG4,NR3C1,INPP5B,ITPKB,KCNH2,MAP4,MAPT,MBD1,KITLG,MPP2,NF1,FSD1,PRPH,APTX,PTPN13,ATG16L1,RGS3,RGS12,RNASEL,RPS6KA2,SH3BP2,ZHX3,SP2,EMC1,TSPYL2,NCDN,MAPK8IP3,ARC,AHCYL2,PARD3,EMSY,EVI5,SEMA3B" Drug 2173_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "NDRG2,APP,ATP2B1,TAOK2,DZIP3,ZNF337,GSDME,DTNA,SIDT2,EFNA3,FAM13A,EIF1,TUBD1,ENO2,CD320,F5,NBEA,TPK1,GALC,SEPT9,GLS,POLL,LILRA2,GPR19,PADI2,SMAD1,SCAMP5,ZNF862,NEK1,PTPA,PPP5C,MAPK8,PTCH1,RIPOR1,RAB3A,TCP11L1,MAP6D1,RAB3GAP1,KDM4B,TSPYL2,RAP1GAP2,DDN,LARP4,CAMSAP2,TCF7L2,R3HDM1,TPD52,TPM1,TPM3,ZKSCAN5,PLPPR2,UBE3B,PHTF2,SENP7" Drug 3237_DN Adenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "AK2,BIN1,APP,ALDH4A1,ATM,CADM3,CFLAR,MTMR2,SPAG9,USP2,TAOK2,RAB28,PLAA,CLCN3,CSF1,RCAN1,FEM1B,MBNL2,DMTN,RASGRP2,MTSS1L,KIAA1109,FHL1,ARFIP1,GRB10,GRM8,MAP4K5,AGFG1,LMO2,TM6SF1,MDM4,KITLG,MMP16,MSI1,NF1,NFYA,CNOT4,PCDH9,PIK3R1,MAPK8,RGS12,ROM1,EMID1,ASAP3,NLGN1,ELMO2,ZKSCAN3,WDTC1,TROVE2,FBXW11,ZNF34,TMPO,VIPR2,EVI5" Drug 4369_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASIC1,DOC2A,DNAH17,GYG2,BAIAP3,CFAP410,CACNA1D,HAP1,CDC42,CDH18,SLIT2,LHX2,STOML1,PICK1,WHRN,CRY2,ABCG1,DBN1,EFNA3,STX2,KAT8,OLFM1,FOXG1,DISC1,PCDH17,RUNDC3A,STON1,HNMT,TJAP1,KCNH2,KHK,KIFC3,MID1,NDUFA5,NNAT,POU3F2,ELOVL2,RIPOR1,RAB3A,TRIM68,ZFHX4,MYH14,TCP11L1,RASA3,ASAP3,SNCA,CLSTN2,VPS13A,PSD3,CRTC1,TMOD1,FLRT2,VAV2,ZIC3" Drug 3476_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASPHD1,ABHD6,ADRA1D,ALCAM,DOC2A,CDC42BPA,FAM131A,APOC1,MARCH3,BTRC,TAOK2,MFAP3L,RABGAP1L,DSCAM,MAMLD1,CELSR3,EIF5,ANKMY1,BAIAP2,CGREF1,DISC1,GNG4,LPAR4,NR3C1,PADI2,HNMT,ITPKB,KHK,LYRM9,NEK1,NPR2,PDE3B,RETREG1,NLE1,SLC25A23,MBOAT7,PEX5,RGS10,NEK11,EPN2,MAPKBP1,SPART,THSD1,NCDN,ANKRD12,SEMA4A,AHCYL2,TMOD1,PARD3,TRPC1,ZKSCAN5,KLC2,REEP1,ACTR3B" Drug 6052_UP Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "TKTL1,C1QTNF1,BIN1,PRX,ALDH7A1,CACNA1I,INA,CHN2,EPS15L1,FAM149A,AKAP6,HAPLN1,CSF1,SNPH,DRD1,ATN1,DYRK1A,ST8SIA3,FHL1,FYB1,GNAO1,GNAS,LILRB4,PRUNE2,GPM6B,GRM7,GRM8,PTGDR2,KCND3,KIT,MID1,PDE1B,ABCB1,CAMKV,PPARA,LRRN3,SAMD9,PTAFR,RASGRF1,RGS12,KANSL3,SLC11A1,KIF21B,ARHGAP26,MAPK8IP3,PHLDB1,WSCD1,TRPM2,TTPA,VAV2,ZNF711,SCG2,AP3B2,JPH3" Drug 5783_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ABHD6,APP,CDC14B,C5,ARHGEF1,SCARB1,ZFYVE9,AKAP7,HAPLN1,SDC3,MRNIP,RGS17,DENND4A,CDKL3,FGF13,FGFR1,SRCAP,MSL3,GPR19,GPR37,SHISAL1,INPP5B,GIT1,NF1,PBX1,PC,PIK3R1,PLCD1,MAPK7,TMEM231,RAD51D,NEK11,NCBP3,ASAP3,AMBRA1,ST6GAL1,SHANK2,BTBD7,TMCC1,LHPP,JMJD6,PDLIM2,WSCD1,TNS2,CHST8,THRA,TNS1,TRPC1,FAM155A,KLC2,XRCC4,NT5M,MPPE1,UBE3B" Drug 5834_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASPHD1,ASIC1,ARID1A,AMPD3,AMT,PPP4R4,CFLAR,MAP7,CCK,REPS2,B4GALT6,CNOT8,CPS1,CTH,SEC14L5,GIT2,ATN1,CNNM1,ETV1,DLC1,FDFT1,TRMO,SORBS1,SEPT9,GLYR1,GPM6A,ICA1,KCNC1,KIT,MAN2A2,AFDN,NF1,NPPA,NTRK2,CCSER2,STRN3,MAPK3,RAB3IL1,NEK11,RYR1,FNDC3A,DZIP1,SLC2A5,ARHGEF40,SMARCA4,MYH15,STX1A,AP4E1,DAAM2,BEX4,CABIN1,NDRG4,KCNAB1,JPH3" Drug 4418_DN Ethionamide [536-33-4]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ARID1A,AMPD3,SEMA7A,CNTNAP1,GAS7,PLA2G4C,ALDH7A1,KIF1A,SYNJ1,CAMK2B,CDC42,FOXN3,CNTFR,SLC4A7,RASSF2,SPOCK2,RUSC2,VPS26C,FGF13,PRKAG2,FOXG1,ALDH1L1,RND1,GLYR1,MSL3,POLL,PCLO,CNTRL,GRM1,ATXN2L,KCNN1,LIG4,LMO2,ADAM22,NF1,NOS1,MTRF1L,PPP5C,CARF,PKNOX2,SLC11A1,BTBD7,PDZD2,RGL1,WSCD1,HEY1,TMOD1,CDK20,ZKSCAN5,HIRA,VAV2,SYNC,EMSY,SLC17A7" Drug 3719_DN Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASIC1,APC,CDK10,ADAM15,ADGRB2,MYRF,CACNA1A,PLEKHB1,TAOK2,ARMC8,SNPH,ARHGAP24,DAPK3,PARD6A,DMPK,CDON,ATN1,DTNA,SIDT2,ING4,LRRC23,ETV1,SEMA4D,ANKFY1,PRELID3A,MSL3,GPM6B,TDRKH,CACFD1,SHISAL1,KIFC3,VWA5A,MAP2,MAPT,MDFI,MT1M,NOS1,SLC11A2,PDE4B,PTCH1,PLPPR1,PTN,RAB3IL1,TCP11L1,SPTAN1,CEP68,ATP11A,DOCK9,AMACR,TFIP11,NT5M,PCBP4,AAAS,RNF146" Drug 2875_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASIC1,PLA2G6,CDC42BPA,CDK13,ATP2B2,CACNA1G,ARHGAP33,CLGN,CHRNB2,TAOK2,LRIG1,CNTNAP2,RASSF2,SPOCK2,SGSM2,ATN1,FAM13A,EGFR,C3orf18,FOXG1,SEMA4D,GAB1,SRCAP,ZNF276,RND1,GPER1,MSI1,MX1,CNOT4,PFKFB2,SERPINE2,PACSIN1,PRODH,PTHLH,RAB3IL1,KCTD17,RAVER2,PKNOX2,WDTC1,SOX2,TSNAXIP1,SPTB,IQSEC2,CDK19,MAPK8IP3,RGL1,ARC,SMG6,TNR,TRO,PDIA2,XRCC4,NUP214,SSPN" Drug 5564_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "FZD9,AQP4,LDLRAD4,CFAP410,CACNA1D,KYAT1,ZFYVE9,SULT4A1,LY86,NRG2,CSF1R,DAPK1,SPOCK2,NTM,ELAVL4,ELN,ZIC4,GABRG2,SEPT9,ALDH1L1,GRIK5,PTGDR2,KLF12,C2orf72,MBP,MID1,AFDN,BCO1,NCAM1,NOVA2,PLXNB1,PURG,PTCH1,ELOVL2,PTN,TMEM156,FRMPD1,SLC9A5,SLCO1A2,RIMS1,ZNF415,TNIK,TSNAXIP1,SPP1,SYT5,KAZN,WSCD1,ZEB1,PCDHGA10,SLC35G2,SLC13A3,TRIM9,KCNAB1,HRASLS" Drug 2087_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "RBM10,BIN1,APP,SEMA4G,ALDH4A1,SLC4A4,ADGRB2,SYNJ2,BTRC,CDH2,TBRG4,SRSF11,FOXN3,STOML1,PDE4DIP,PPP6R2,RUBCN,DLG3,MAMLD1,EDNRA,FAM13A,COQ7,TUBB4A,PRRC2B,GPR19,SLC2A6,SHISAL1,ITPKB,KIFC3,NUCB1,POLG,PRKAR1B,PTN,SH3TC2,RGS7,TCP11L1,RXRA,IL17RB,SLC4A3,LIMS2,RBM34,IQSEC2,LHPP,FAM168A,MCF2L,IQCE,ARHGEF12,AHCYL2,TMEM121,CABIN1,SPHK2,WNK1,HPS4,NUP214" Drug 4272_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "APOC1,SYNJ2,SCAPER,SPAG9,KRIT1,CCNT1,WHRN,SLC4A7,CNTNAP2,SMG7,MBNL2,RRAGB,FYN,GAD1,SPIN1,FERMT2,AGFG1,IFI16,IL6ST,DIPK1A,JAK2,KCNK1,MMP16,TAGLN3,MYO6,NFIX,NUMA1,PCDH9,PIK3R1,CCSER2,SMIM7,STRN3,LRP12,PRKAB2,PTHLH,PTN,RGS4,SLC25A36,FBXO11,SPTAN1,PBLD,KIAA1107,EHBP1,TCF4,TCF7L2,ARHGEF12,DICER1,TMPO,SF1,WNK1,NAV3,KCNAB1,EPM2A,FXR1" Drug 4313_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "LTBP4,FAM135A,ANK2,APAF1,ASPA,PTCH2,SLC4A4,SYNJ2,MTMR3,BAIAP3,CALB2,COL9A2,IFFO1,NCOR2,CNTNAP2,CYBB,RIPOR2,MAML1,BRINP1,MFAP3L,DTNA,ABCC9,EGFR,BAIAP2,CAMSAP1,DCTN2,EFCAB2,B3GAT1,GPER1,GRIK5,PTGDR2,KCNJ9,PACRG,MOBP,NF1,NPTX2,NUMA1,OPRL1,PBX1,CDK18,TNPO2,ACSS3,RFX2,PKNOX2,SLC11A1,SLC15A2,SPP1,RBM26,ATP10B,TROVE2,CRTC1,LAT2,SF1,ZIC3" Drug 4181_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASIC1,ADCY2,CDC42BPA,SEMA7A,APC,APLP1,CDK10,DNAH17,CRLF1,CNTFR,TCEAL2,CRMP1,RIMS2,SRGAP3,HIPK3,PLXNC1,ING4,ELN,STX2,ERCC2,ANKMY1,DLC1,OLFM1,FAM49B,KHDRBS3,HBS1L,AHDC1,LYVE1,ADAMTS13,KCNK2,KCNN1,NNAT,PDE1C,PPP2R2B,MAPK10,RAD52,GTDC1,SLC6A8,SLN,TNIK,ZHX3,VAMP1,PLCB1,ARC,SYT5,KAZN,SIN3B,SZT2,FLRT2,WIPF1,KLC2,XRCC4,ZFP37,EPM2A" Drug 7394_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "MRTFA,PDE8B,ASTN1,SLC4A4,CFLAR,BTRC,CAMK2A,DLGAP2,FOXN3,ARHGEF10,PDE4DIP,CTNND2,SPOCK3,DRP2,DTNB,EFNA3,ETV1,FGF13,FYB1,ERAP1,GNG3,GPR22,ELOVL5,KIFC3,MGAT3,MT1M,NF1,CLDN11,DUSP26,FA2H,PPARA,PPP5C,BCAS3,PTPRN2,RAB3A,RAD52,ENOX1,ZDHHC14,ROM1,TRAPPC13,FRMPD1,DZIP1,SLC2A5,SLC20A2,RBM34,SPTAN1,IQSEC2,ADGRL3,ZNF34,VIPR2,NSD2,XRCC4,SCG2,SENP7" Drug 3674_DN Nitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ACTN1,MRTFA,APC,APP,CDK13,CACNA2D2,PLEKHB1,LHX2,HOMER3,CRY2,NCOR2,HDAC9,DAPK3,DMPK,DSCAM,DUSP9,ING4,MRNIP,FGFR1,CSPG5,PCDH17,GLUL,GNAS,GPR17,CACFD1,ATXN2L,TJAP1,KCNB1,MAP4,MAPT,TM6SF1,CNOT4,ODF2,WDR25,RAD51D,ENOX1,GAL3ST4,ROM1,NEK11,FNDC3A,BTBD7,EMC1,ARHGAP26,SS18,MCF2L,AMACR,VGF,LAT2,NSD2,ZNF74,WNK1,HPS4,PCBP4,KAT6A" Drug 7219_UP Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ASIC1,AGT,AK2,LTBP4,CDC42BPA,APBA2,CADM3,LDLRAD4,CAMK2B,RCBTB2,TAOK2,NECTIN3,HAPLN1,NCOR2,FEZ1,MFAP3L,EFNB3,RASGRP2,ATP8A1,AGAP2,FYB1,ERAP1,SRCAP,GFER,SPACA9,HNMT,KCNJ4,KCNJ5,KIF5C,LSS,PACRG,KITLG,MITF,ADAM22,MYO7A,NASP,NEFM,CNOT4,NLE1,SLC25A23,PLTP,RGS12,NTNG1,SLC11A1,WDTC1,KIF21B,PHLDB1,SYT5,TACR1,PCDHA6,SLC44A1,TMOD1,GDPD5,SSPN" Drug 4589_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ANK3,CDK13,ADAM15,ADGRB2,CACNB2,TPP1,AKAP7,CPS1,AATK,SLITRK5,FAM131B,ARHGAP24,TBC1D5,DBT,SIDT2,LRRC23,ETV1,ZNF589,INPP5K,C1QL1,GLRB,STON1,NUDT21,GRM1,GUCY1A1,GUCY1B1,HLF,ITPKA,JAK2,KHK,MT1M,MX1,LYRM9,ZNF862,NDP,NF1,CNOT4,PAK3,PDGFRA,TNPO2,PRKACB,GRAMD1C,ELOVL2,BEND5,ZFP30,ARHGEF40,BTBD7,LIMCH1,ARHGAP26,LHPP,ELOVL4,KIAA1107,TCF7L2,ZNF34" Drug 5229_DN troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "ABHD6,LTBP4,CDC42BPA,SEMA4G,ARRB1,BRINP2,GYG2,CACNA1I,CACNA1D,KYAT1,CCNT1,CRLF1,PLEKHB1,SLIT2,VAX2,PPP6R2,GPRASP1,MAML1,EFNA3,ENO2,LRRC23,POMT1,PRELID3A,USP19,TDRKH,ELOVL5,IGSF1,INPP5B,MID1,MITF,MMP16,SMIM7,FSD1,MED1,PRKAR1B,TMEM104,WDR25,FAM184A,TCP11L1,SH3BP2,ASAP3,SYBU,SMARCC2,WDTC1,ZHX3,THSD1,SEMA4A,TMEM121,CABIN1,TRIO,VGF,VIPR2,REEP1,PCBP4" Drug 2649_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "BIN1,APOC1,ATM,ST3GAL5,CLCN3,QKI,ARMC8,COL4A5,PDE4DIP,GIT2,DNAJC6,FBXL5,DSCAM,DTNA,EFNA3,EIF5,ING4,STX2,KIAA1109,FGFR1,FHL1,FAM49B,DISC1,MSL3,GPR19,GPER1,DHX35,KCNH2,KCNJ3,MAP4,MBNL1,GIT1,NF1,RGS3,RNASEL,ZNF821,SGK1,AMBRA1,FBXO11,PEX26,INTS9,SOX3,EMC1,TROVE2,SS18,CEP68,ASTN2,TACC1,TCF7L2,HIRA,WRN,SF1,SNX27,MPPE1" Drug 5979_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.39E-05 6.83E-01 2.15E-04 2.44E-03 54 195 "LDLRAD4,CD86,CBFA2T2,NEURL1,ARHGAP33,CBARP,ABCG2,CPS1,PDE4DIP,SPOCK2,ATN1,DTNB,EDIL3,FCF1,TNK2,DLC1,ATP8A1,KIAA1109,FGFR1,FLT1,PNMA2,GAB1,ERAP1,DISC1,POLL,GRM1,IGFBP1,KCNB1,MIA2,MMP16,PDE4A,PDGFRA,SERPINI1,RETREG1,ENOX1,BEND5,RGS4,RGS10,RGS12,CARF,FRMPD1,ARHGAP26,NFASC,MCF2L,ADGRL3,HIF3A,GPR161,TMOD1,TMPO,R3HDM1,ZKSCAN5,ZNF24,PARP6,SENP7" Drug CID000003784 isradipine Stitch 1.41E-05 6.91E-01 2.17E-04 2.47E-03 33 100 "ASIC1,AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,ASIC3,EDN1,CACNG7,CACNG3,CACNG2,GAD2,KCNMA1,PKD1,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SIRT2,SCN3B,PEG10,TPCN2,NETO1" Drug CID000006468 phencyclidine Stitch 1.42E-05 6.96E-01 2.19E-04 2.49E-03 51 181 "ACHE,FMNL2,PRX,ATP2A2,BCHE,CALM1,CAMK2B,FMNL3,CHRNA4,CHRNB2,CRMP1,DPYSL2,SLC25A18,DRD1,DYRK1A,VPS26C,AFF2,FOLH1,DNER,STMN2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HNRNPK,HTR2A,INPP1,KCNA1,NDUFA5,NOVA2,OPRL1,SLC1A2,SLC14A1,HECW1,SPP1,DAAM2,KCNT2,FXR1" Drug 3819_UP Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.42E-05 6.96E-01 2.19E-04 2.49E-03 51 181 "ACTN2,PRX,ASPH,NRP2,GYG2,CACNA1I,CDK5R2,CACNA1D,KALRN,USP2,CLU,WHRN,KIAA0513,ZNF804A,RUSC2,EZH1,BAIAP2,FLT1,AFF2,SORBS1,PDLIM5,PRELID3A,NSG1,B4GALNT1,RAB30,FERMT2,GRK4,MUM1,MARK1,MYO7A,NCF2,NRCAM,NTRK3,OXTR,PALM,GPR85,PROX1,TTLL7,HSPA4L,HKDC1,KIF13A,MAPK8IP3,TRIM2,SYNE1,DAAM2,WBP2,UBE3A,UCHL1,SPHK2,NAV3,MVB12B" Drug CID000003355 flecainide Stitch 1.43E-05 6.99E-01 2.20E-04 2.50E-03 26 71 "SERPINA3,ASIC1,CACNA2D1,CACNB2,ASIC3,DPP6,KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCND1,KCND2,KCND3,KCNH2,KCNK1,MYL3,KCNIP2,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug 261_DN cyclosporine A; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "AK2,ALK,BIN1,ANK1,BCAS1,ASCL1,RASL11B,ATP2B2,RAB29,HAP1,CH25H,CD38,ARHGAP33,B4GALT6,JAM2,LHX2,RAB28,ARHGEF10,SIPA1L1,PPP6R2,DAPK1,GIT2,PLEKHA1,ING4,HSD17B14,STX2,ETV1,IQCG,ATP2C1,ATP8A2,RUNDC3A,GLS,ZNF638,GNAO1,MCHR1,AP4S1,LAMA2,NPR2,NPTX1,NTRK3,OMG,PDE4D,RETREG2,PPP2R5C,CCDC40,RASGRF1,RGS3,RNH1,SLC1A2,SHANK2,LIMCH1,HECW1,TBL1X,TMEM121,GPR161" Drug 4598_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ACTN1,ALK,SCAPER,BAIAP3,CACNA1A,NEURL1,MAGI1,ADGRG1,RAB28,HOMER3,AKAP5,SH2B1,CSF1R,CNTNAP2,MFAP3L,SGK2,ELAVL3,C1orf61,CSPG5,ZMYND11,DISC1,MSL3,POLL,GNAL,HLF,HMGB1,KCNJ4,KCNN1,KIFC3,MDM4,MN1,LYRM9,NF1,OPCML,PDE4B,SAMD9,RAB3IL1,FAM184A,KHDRBS2,GAL3ST4,RGS4,RNASEL,GSTCD,TCP11L1,IL17RB,DOCK10,BCAN,CCDC88A,ZNF415,SYN2,MCF2L,RPGRIP1L,TRIO,CADM1,PCBP4" Drug 3164_UP Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "AMPH,APP,ZSCAN18,DDX3Y,NOL4,AZGP1,NRP2,CAMK2B,CD38,B4GALT6,HAPLN1,RGS6,RIPOR2,ARHGAP24,JAKMIP2,C2CD2L,DRD1,DYRK1A,HEYL,CALCRL,FOXG1,FOXF2,GLI2,RAB30,GNAL,PTGDR2,INPP5B,KCNB1,MAG,MEF2C,AFF1,AFDN,ADAM22,MYCN,NEUROD1,SLCO1C1,TREM2,PLXNB1,PMP2,PTX3,CCDC40,RASGRF1,KCTD17,CXXC4,ZSWIM8,IZUMO4,PLCB1,SYN2,PCDHGA10,RIMBP2,LILRA4,AMACR,CA14,ZNF45,NT5M" Drug 3014_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "C3orf14,NDRG2,ADORA3,TRMT9B,MARK4,NUMB,ATP2B2,AZGP1,CACNB2,THSD7A,DLGAP1,CHI3L2,CHRNA4,LHX2,ZFYVE9,CTNND1,BRINP1,HEYL,AASS,EIF4G2,SORBS3,LRRC23,RASGRP2,C1orf61,AGAP2,AFF2,GNAL,GNAS,GNG4,AP4S1,KCND3,MAP4,MAPT,MOBP,TAGLN3,MYBPC1,MYT1,NNAT,PMP22,PROX1,MAP6D1,ZNF821,MRAS,ANKRD6,ZNF415,SPTAN1,IQSEC2,ATP10B,WSCD1,RIMBP2,PARD3,CDK20,TRO,FAM155A,OSBP2" Drug 2011_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASIC1,ADORA1,C1QTNF1,SPARCL1,APBB2,ALDH4A1,EIF4G3,BCL7A,SLC25A14,CD86,CREM,CRY2,AATK,C2CD2L,ELAVL4,TUBD1,KAT8,TMEM164,SUCO,KCNMB4,AGFG1,TJAP1,MYL3,MYO5A,NF1,OCRL,PFKFB3,RETREG1,NLE1,ST8SIA5,POLG,MINDY2,PPP2R5C,MAPK10,MASP1,SNRK,RAP1GAP,KLHDC8A,STUM,SH3BP2,ITSN1,BTBD3,KBTBD4,SLC12A2,ELMO2,SPTB,SPART,POGZ,FAM208A,CRTC1,R3HDM1,NPL,HIRA,TRIM9,EVI5" Drug 5862_DN Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "KIDINS220,EP400,APP,MARCH3,ZBTB10,NCOA1,BCL2L2,CFLAR,C5,HIP1R,RCBTB2,CNOT8,RAB28,CLCN4,FADS2,NIPBL,SH2B1,APPL1,PPP6R2,TBC1D5,GIT2,SMG7,DYNC1I1,GPHN,EFEMP1,ST3GAL6,FGF13,TRMO,ZNF276,SCAMP5,TAGLN3,CDK14,KCTD15,NLE1,SNRK,RAB3A,RAP1GAP,ZDHHC14,BSDC1,CHD9,TMCC1,SPATA7,SS18,NXT2,MAPK8IP3,ELOVL4,EXOC7,WWC1,IQCE,RBFOX2,CADM1,LMF1,ZFAND5,PRDM2,NAV3" Drug 3111_UP Iodipamide [606-17-7]; Up 200; 3.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASPHD1,ASIC2,ADD2,ALAD,PPP4R4,PDXK,PLA2G4C,ADAM23,MPDZ,BCL2L2,NRP2,BAIAP3,BTRC,LARGE1,MAGI1,ABCG2,AKAP7,CREB5,ABCG1,MICAL2,PDE4DIP,DAPK3,DYRK1A,SIDT2,CELSR3,SORBS3,SPEG,FER,KIAA1109,AFF2,PCDH17,ZNF276,GPR22,CELF3,KLF12,KCNQ3,NRCAM,KCNK10,PCDH9,NECAB2,LRRN3,RAD52,ZDHHC14,MORC4,RGS10,RGS12,ITSN1,HKDC1,PREX2,TNIK,SPTB,ELOVL4,TACR1,AHCYL2,FLRT2" Drug 3827_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ARID1A,AK2,DOC2A,GAS7,BAIAP3,CACNB2,CDC42,PLEKHB1,LHX2,STOML1,RAB26,AKAP5,IFFO1,AATK,SRGAP3,ARNT2,EDNRB,EFNA3,ETV1,DLC1,FGF1,DCTN2,FYB1,TRAF3IP2,ITGA7,KIFC3,LAMA2,LYRM9,NOS1,PENK,ZCWPW1,ARHGEF10L,SBF1,SLC1A7,SLC2A5,SLC6A11,SLC9A5,ZNF334,OGDHL,KDM4B,SOX15,ZHX3,LHPP,PLCB1,KAZN,MCF2L,EXOC7,CHST8,SEZ6L,TRIO,CADM1,FLRT2,VLDLR,REEP1,DPF3" Drug 1519_DN Edrophonium chloride [116-38-1]; Down 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "OSBPL1A,FAM131A,PPFIA3,CAMK2G,CCNT1,SLIT2,SULT4A1,CREM,SIPA1L1,PDE4DIP,KIAA0586,RABGAP1L,TMCC2,DTNA,HIPK3,CNNM1,SIDT2,EFNA3,TESK2,MPP6,ARFIP1,GLYR1,RAB30,GRB10,DIDO1,HSF2,INPP5B,IPO5,MAP4,NFYA,FSD1,MAPK8,SIDT1,ARHGEF10L,TRAPPC13,ZNF821,SH3BP2,FAM102A,FUZ,FAM214B,EFHD1,ZCCHC24,MAPK8IP3,PLCB1,ARC,ATP11A,TCF7L2,CRTC1,TMOD1,RBFOX2,ZNF24,SPHK2,GDPD5,ST7,SSPN" Drug 3068_UP Meglumine [6284-40-8]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ADD2,ADORA1,CASK,ARRB1,THSD7A,ENTPD6,NEURL1,KCNAB3,CHN2,CHRNA4,SLC24A2,STOML1,ABCG1,RIPOR2,KIAA0513,AK5,CDON,E2F5,EFNB3,VPS13B,LRRC17,RASGRP2,FHL1,GAD1,ALDH1L1,GCNT2,GPM6B,ADAMTS13,GRIN1,HNMT,HTR5A,KCNJ5,MAP4,MGAT3,TAGLN3,MYO6,OMG,PENK,CCSER2,PRKAR1B,TMEM255A,RAD52,RGS12,STUM,FUZ,EPN2,TSNAXIP1,SPTAN1,SEPT8,CHST8,KCTD2,SEZ6L,TRPC1,VAV2,VGF" Drug 251_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "LTBP4,BIN1,ANK1,APBA2,CDK10,PDXK,EIF4G3,ATP2B2,ATP6V0A1,AZGP1,NDST3,SIPA1L1,DZIP3,SDC3,GIT2,DCC,ENO2,STX2,CACNG2,TXNL4A,GLS,GRIK5,GUCY1A2,FAM107A,RNFT2,HLF,KCNJ4,KIFC3,KIT,L1CAM,MYL3,NPR2,PNMA3,PPP3CC,MAPK8,PYGM,RIPOR1,KHDRBS2,GAL3ST4,FOXRED2,ASIC4,RASA3,FRMPD1,NPAS3,ASTN2,ATP11A,KAZN,WWC1,AHCYL2,SEZ6L,LMF1,WIPF1,TRIM9,ZNF184,NUP214" Drug 2632_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASPHD1,ADD2,KCNAB2,APLP1,MARK4,DDX3Y,N4BP2L1,RGS9,NRP2,CACNA2D1,CAMK2B,TAOK2,CPS1,PDE4DIP,RIMS2,DCT,MYEF2,DMPK,ST8SIA3,EDN3,EIF4G2,NCALD,RASL12,FGFR1,EFCAB2,DISC1,GCNT2,GPR162,RUNDC3A,GLS,GRIN1,GSTM5,LMO2,MDFI,AFDN,MN1,NDUFA5,PCDH9,PENK,PIK3CD,PTHLH,MAPKBP1,DOK5,ZSWIM8,ERC1,IQSEC2,ST5,MLC1,FAM189A1,AP4E1,TRPM2,VAV2,SPHK2,NUP214,DPF3" Drug 3322_UP Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ARID1A,NDRG2,AMPD3,APBB2,ALDH4A1,GYG2,HAP1,FOXN3,LHX2,RAB28,AKAP7,WHRN,CSF1,ARHGEF4,PPP6R2,DCAF8,CTIF,RUSC2,TRAPPC9,DSCAM,DTNA,CELSR3,F3,SEPT9,GNG4,GRIK5,ATXN2L,ELOVL5,MPP2,NOVA2,PLCD1,PLTP,TNPO2,PPARA,GRAMD1C,PTN,RIPOR1,BSDC1,SBF1,FAM102A,AMBRA1,SLC9A5,ZSWIM8,ST5,PHLDB1,FAM168A,ROBO3,GPR161,SLC44A1,FLRT2,PLPPR2,KCNK12,DNALI1,HPS4,SLC17A7" Drug 2127_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ADRA1D,KCNAB2,SEMA4G,MARK4,ASPH,CFLAR,CCNT1,ARHGEF2,CACNA2D2,ZFYVE9,HOMER3,NRG2,CSF1,GPRASP1,SPOCK3,FAM13A,ZNF589,SCARA3,GALC,ARFIP1,HTATSF1,GNAS,PRRC2B,GRIK2,GRM1,SHISAL1,INPP5B,ITGA7,KIF5C,ZNF862,NPR2,SMIM7,FSD1,PPP5C,SAMD9,RAB3A,RAB3IL1,RGS10,NUDT11,SBF1,SIRT2,IFT122,SPTAN1,RAP1GAP2,ELOVL4,ATP11A,CRTC1,AHCYL2,THRA,TMPO,TRPC1,SSBP2,WIPF1,ZNF32,ST7" Drug CID003034747 C070379 Stitch 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ADORA3,AGT,SLC4A4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1B,CACNA1E,CALM1,CAST,CCK,LRBA,CDC42,CHRM1,DNM1,EDN1,PTK2B,FGF1,CAMKK2,ATP2C1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HPCA,HSF2,MYLK2,JAK2,KCNJ3,NOS1,OGDH,P2RX7,PIK3R1,PPP3CC,PRKACB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,RAP1GAP,RYR1,RYR3,MAPK12,TPD52,TRPC3,SCG2" Drug 3904_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ACTN1,ARID1A,ADCY6,SRPX,AMPD3,AMT,GAS7,BMP7,CAMK2B,ARHGEF1,CRLF1,CSF1R,USP6NL,EGFR,PLXNC1,ERCC2,ZNF589,SCARA3,HBS1L,GCNT2,GSN,TJAP1,VWA5A,KITLG,MMP17,ADAM22,NDUFA5,NPR2,NPTX1,LRP12,MAPK8,MAPK10,FAM120C,NKAIN1,CCDC40,RAD52,GTDC1,SBF1,PPP1R9A,FAM214B,BTBD7,SMARCD3,MAPKBP1,RBM34,ZCCHC24,ARHGAP26,AHCYL2,ZNF34,TK2,TMOD1,ZMYND8,SYNC,EVI5,ITM2C,RNF170" Drug 603_UP nifedipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASIC1,MTUS1,PKP4,CHRD,RASL11B,HAP1,CDC27,CHRM4,NIPBL,CNTFR,CDC42BPB,ARHGEF10,CYBB,C2CD2L,DLG3,DYNC1I1,SUGP2,MBNL2,MRNIP,CALCRL,EPHB1,CDKL3,TUBB4A,ZNF589,FGFR1,TRMO,MCHR1,RNFT2,ARHGAP19,IL6ST,ITPKB,KIF2A,STMN1,MMP16,MMP17,CNOT4,NRGN,NTRK3,SETD4,OMG,PLCD1,RETREG2,PACSIN1,MAPK8,PTPRD,ACSM5,BSDC1,SH3BP2,KIF16B,ZNF430,TMCC1,SON,ZCCHC24,KIAA0930,VPS35L" Drug 4082_DN Yohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASIC1,MRTFA,AQP4,DNAH17,ATP1A3,ALDH7A1,NRP2,CACNA1I,AKAP5,PDE4DIP,ARHGAP24,CTIF,BRINP1,MFAP3L,CHRDL1,CDON,CELSR3,ELN,MTSS1L,ST3GAL6,CGREF1,ZNF44,SRCAP,C1QL1,LPAR4,GRIK2,MAPT,MATN3,MYT1,NF1,NOVA2,SLC11A2,ODF2,PDE4D,PIK3R1,PPARA,MINDY2,PLPPR1,PTPRB,FAM120C,PID1,KHDRBS2,RGS4,DZIP1,SLC4A3,SLC1A7,LIMS2,SNCA,ADGRL3,SYNE1,PCDHA5,TK2,TPM1,OSBP2,TIGD6" Drug 5391_UP Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASIC1,ARID1A,ADRA1D,PLA2G6,MRTFA,PPFIA2,APAF1,MARK4,BTRC,CA4,CAMK2B,CAMK2G,USP2,CDH18,ZFYVE9,CNTFR,CPS1,DCAF4,NOS1AP,RIMS3,RUSC2,NTM,TMCC2,DRD1,ATN1,SNX29,FHL1,FYB1,TMEM8B,MSL3,GPM6A,GPM6B,RASSF8,JAK2,SMAD1,MAP4,CD200,ADAM22,SLCO1C1,SLC11A2,LRRN3,DCHS2,C1orf54,SLITRK3,ZKSCAN3,ZHX3,NPAS3,MLC1,EXOC7,SMG6,DMXL2,TCF7,HIRA,LAT2,WNK1" Drug 5634_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "DPF1,APAF1,APOC1,PRX,ASCL1,NRP2,KSR1,FUBP1,ARHGEF1,RAB33A,DNAJB5,CNTFR,WHRN,CLIP3,AATK,CSF1,NOS1AP,EDNRB,EFNA3,EFNB3,PHF20L1,TUBB4A,DISC1,PCLO,GRM1,GSTM5,SOX21,HTR2A,ICA1,ZNF862,NF1,CDK14,NECAB2,POU3F4,MAPK7,MAPK8,CNTLN,CCDC40,TCP11L1,ASIC4,STUM,HKDC1,SLC1A7,PKNOX2,KDM4B,SPTB,SEMA4A,CUX2,DAAM2,FLRT2,VAV2,SPHK2,STMN4,KCNAB1,EPM2A" Drug 7229_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASPHD1,CDC42BPA,EPB41L5,BCL7A,CFLAR,MTMR2,C5,CACNA1D,SYNGR3,CRLF1,ARHGEF6,COL4A5,FAM169A,EDRF1,FBXL5,SMG7,PARD6A,DLG3,RCAN1,EDNRA,CDKL3,EZH1,F3,FOXG1,SEMA4D,SMC2,B4GALNT1,SYT17,GLS,GPR37,GRB10,HNMT,INPP5B,KIF5C,MAP4,MAPT,NUMA1,SETD4,STRN3,LRP12,SAMD9,TMEM104,RIPOR1,SEC61A2,SBF1,PPP4R3A,ARFGAP1,POGZ,MAPK8IP3,NSFL1C,TCF7L2,TRIM2,ATP13A2,TFIP11,NUP214" Drug 7404_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ASPHD1,ABHD6,ADORA1,C1QTNF3,APBB2,PPP4R4,ALDH4A1,MPDZ,ST3GAL5,NEURL1,TPP1,FAM189A2,QKI,LY86,NECTIN3,CREM,CRY2,PPP6R2,RIMS3,DNAJC6,JAKMIP2,MAGI2,HIPK3,EFNB3,TESK2,BAIAP2,FHL1,PRELID3A,HBS1L,SYT17,ALDH1L1,GLI2,CACFD1,KLF12,INPP1,KCNN1,MBD1,ADAM22,NNAT,NOS1,CNOT4,NTRK3,SERPINE2,MBOAT7,PRPH,ZSCAN2,SYBU,IQSEC2,SS18,VAMP1,ANKRD12,CDK20,VLDLR,ZBTB14,EPM2A" Drug 5755_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "SEMA7A,APBB2,APC,APOC1,CAMK2B,PLEKHB1,CLCN4,ARMC8,WHRN,SNCAIP,CSNK1E,ARHGAP24,RIMS3,DCC,DTNA,ING4,KCNMB2,IGSF6,REEP2,HPCAL4,FOXG1,C1orf61,COPS8,GSTM5,IL1RAPL1,SOX21,PADI2,HTR2A,ICA1,SHISAL1,ITIH2,LMO2,VWA5A,AFF1,NDUFA5,NELL2,NF1,NOVA1,NTRK2,PDE4D,PFKFB2,STUM,SLC1A7,PPP4R3A,PKNOX2,ARHGEF40,SLC12A4,WDTC1,KIF21B,TSNAXIP1,IQSEC2,PLCB1,ASTN2,ZNF225,KCNAB1" Drug 2908_DN Nifurtimox [23256-30-6]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ACTN2,GRAMD1B,PPFIA1,APC,GAS7,ADAM23,OSGIN2,ENTPD6,TAOK2,LHX2,NMT2,CRY2,PDE4DIP,PPP6R2,GPRASP1,RUSC2,EXOG,ECM2,TOM1,PLXNC1,PTK2B,EVL,GAB1,ZNF44,ERAP1,SRCAP,ADAM28,CRCP,PCLO,PADI2,MEF2C,OXTR,CCSER2,PLCL1,PMP22,PILRA,PKN2,BEND5,RET,TTLL7,SEC14L1,ZNF821,RASA3,DBNDD2,STX1A,CAMSAP2,PDLIM2,OBSL1,PARD3,TNNT1,TPM1,MAP3K12,PRDM2,PRDM10,KCNAB1" Drug 5570_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "DPF1,ADORA1,KIAA1324,ADGRF5,ALK,AMPH,AMT,GAS7,CDC14B,ASPH,KSR1,CACNA1I,CAMK2B,CDH2,CHI3L2,ZFYVE9,CSF1,CSF1R,CNTNAP2,RASSF2,INTS1,DCC,DRD1,DUSP9,EDNRA,EGR3,CORO2B,FGFR3,GLYR1,GNAS,STMN2,ATXN2L,C2orf72,KCNK2,LMO1,MAOB,MYO7A,MYT1,TREM2,PDE1C,PDE4B,PFKFB4,ELOVL2,ZMAT4,RFX2,MYH14,FRMPD1,PDZD2,SYN2,TRIM2,DICER1,HEY1,TRPM2,SLC17A7,NLRP3" Drug 3003_UP Reserpine [50-55-5]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "C1QTNF1,ASCL1,CCDC181,ATP2B3,MYRF,CFAP410,CALB1,TMEM257,SULT4A1,RAB26,ARHGAP32,MFAP3L,EGR3,TNK2,MRNIP,ERBB4,OLFM1,AGAP2,B3GAT1,GABRA2,SRCAP,POLL,GRIK1,GRIK5,GRIN1,CACFD1,RNFT2,ATXN2L,SCIN,NCAM1,NFIX,OMG,OXTR,PCSK5,PDE1C,PFKFB2,PLCL1,FSD1,RGS4,NEK11,ASAP3,PREX2,PALLD,KDM4B,ZSWIM8,ZC3H13,SYT1,TIAM1,SEZ6L,RUNDC3B,VGF,SPHK2,PMEPA1,HRASLS,SSPN" Drug 4077_DN Diflorasone Diacetate [33564-31-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "ADRA1D,MTUS1,TRMT9B,AQP4,DNAH17,ASTN1,ATP1A3,ALDH7A1,NOL4,LARGE1,NRXN3,ABCG2,DNAJB5,RAB26,CNTFR,AKAP5,TCEAL2,CRMP1,PDE4DIP,ARHGEF4,SNPH,CTIF,MFAP3L,CDON,ST8SIA3,SIDT2,LRRC23,MTSS1L,ST3GAL6,EFCAB2,ZNF44,GNAL,LPAR4,ICA1,MGAT3,MOBP,MYT1,NOVA2,PLXNB1,PLPPR1,PTPRB,PEX5,KHDRBS2,RGS4,RGS7,IL17RB,ZNF821,DOCK10,SLC1A7,PPP4R3A,ACSBG1,MCF2L,SYNE1,OSBP2,NAV3" Drug 338_DN "azathioprine, USP; Down 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "KDM5D,KIAA1324,LTBP4,ATM,SLC2A11,CADM3,MTMR2,GYG2,INA,CD86,CD38,CHRM4,ARHGEF10,DTNB,VPS13B,EFS,CEND1,ZIC4,ZMYND10,FGFR1,IQCG,KHDRBS3,GABRA4,GABRG2,NEU3,HPGDS,LILRA2,GPR37,NXPH3,HSF2,KCNQ3,STMN1,MBD1,MYO6,MYO7A,NTRK3,FERMT1,PREX2,KBTBD4,SLC12A4,NMNAT2,ZC3H13,SPART,SSTR2,ZC4H2,SYT11,TACC1,PCDHA5,CDH22,ZMYND8,TMPRSS5,TTPA,TUBB1,LMF1,NUP214" Drug 6690_DN Flucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.45E-05 7.12E-01 2.21E-04 2.52E-03 55 200 "CDC42BPA,ALDH4A1,KIF1A,NRP2,ST3GAL5,KRIT1,CLU,DNAJB5,IQCK,CNTNAP2,SLITRK5,ZBTB24,SGSM2,RABGAP1L,CHRDL1,EXOG,TOM1,EFNB3,COQ7,LRRC23,FECH,CAMSAP1,SCARA3,TMEM8B,GLI2,GPM6B,MUM1,HNMT,DIPK1A,NUMA1,PLCD1,PPARA,GRAMD1C,PTN,ZSCAN2,TMEM231,KHDRBS2,RGS10,KIRREL1,SCG5,FBXO11,PPP4R3A,SMARCD3,LIMCH1,UHRF1BP1L,DDN,THSD1,MAPK8IP3,CEP68,VAMP1,VPS13A,ZKSCAN5,EVI5,HPS4,KCNAB1" Drug 2130_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.49E-05 7.32E-01 2.28E-04 2.59E-03 52 186 "BIN1,CDC42BPA,APAF1,CADM3,BMP7,CAMK2B,MAP7,CD86,SYNGR3,CLGN,DNAJB5,SLC4A7,CREM,SH2B1,MICAL2,CSNK1E,SIPA1L1,PPP1R16B,DOCK4,DBT,CDON,DTNA,FAM13A,EGR3,EIF1,VPS13B,FOXG1,IQCG,TMEM8B,RUNDC3A,HMGCR,MAP4,NFYA,NNAT,NUMA1,OLR1,PDE4A,ENPP2,RIPOR1,ZFHX4,TMEM206,MAP6D1,PALLD,ZCCHC24,ZC3H13,CEP68,ADGRL3,TBCEL,RBFOX2,RUNDC3B,CLDND1,ZFP37" Drug CID000036511 Substance P Stitch 1.50E-05 7.34E-01 2.28E-04 2.60E-03 84 343 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,AGT,MRTFA,ARHGDIA,CACNA1B,CACNA1E,CALB1,CALM1,CCK,CCKBR,CHGA,CHRM1,CHRNA4,CHRNB2,SULT4A1,CNR1,PLCXD3,DMPK,DRD1,EDN1,EDN3,EDNRB,ENO2,PPP1R1B,B3GAT1,GAD1,GAD2,GAP43,GFAP,GFRA1,GFRA2,CRCP,MCHR1,GRIA1,GRIA4,PLCD4,GRIN2C,GRIN2D,HRH3,TNFAIP8L3,IGF1,LSAMP,KITLG,NOS1,NPY,NPPA,NTRK3,OMG,OPRL1,CLDN11,PDYN,PENK,PLCB2,PLCD1,MAPK3,PRPH,RET,FBXW7,RYR3,MAPK12,SP2,SP4,SST,SSTR1,SSTR2,PLCB1,SYP,TAC1,TAC3,TACR1,ZFP91,TRH,NTSR2,CADM1,UCHL1,VIPR2,NPDC1,SCG2,SLC17A7,JPH3" Drug 1058_UP SAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.50E-05 7.36E-01 2.29E-04 2.60E-03 49 172 "ABHD6,ADD3,ALAD,ST3GAL5,CBFA2T2,AKAP12,KIAA0513,RIMS3,GIT2,DNAJC6,OPTN,EFNA3,EFNB3,MBNL2,STX2,EXTL2,TAOK3,BAIAP2,DPYSL4,FYN,GLS,RAB40B,STON1,KIF3A,PADI2,DIPK1A,KIF5C,MXI1,NEK1,PCDH9,PKIA,PRPH,SH3BGR,SH3GL3,PPM1E,WDR47,ELOVL4,RGL1,STXBP1,ACSBG1,SYT11,VAMP1,TACC1,TRIM2,HEY1,NPL,SSBP2,DNAJC12,REEP1" Drug CID000003800 NSC613009 Stitch 1.53E-05 7.49E-01 2.33E-04 2.65E-03 40 131 "MYH7B,ARHGDIA,C5,CBS,CDC42,CFL2,CLTC,CABP1,MYRIP,CALY,DCTN1,EFNA2,ABI2,PTK2B,FCGR3A,FER,ACTL6B,GAB1,GALC,GOLGB1,RAPGEF1,GSN,MYLK2,SCIN,ITGAM,ITPKB,MAP4,MYO5A,MYO7A,PIK3R1,PTH1R,PTK2,RYR1,RYR3,SLC12A2,SLC14A1,ARC,ACTR6,TRPC1,TRPC3" Drug CID000001915 "8-bromoguanosine 3',5'-cyclic monophosphate" Stitch 1.55E-05 7.58E-01 2.35E-04 2.68E-03 77 308 "ADCY5,ADCY6,ADCY8,ADD3,SLC12A5,AGT,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,CAMK2B,CAMK2D,LRBA,CACNA2D2,CHRM1,MYL6B,CNGA3,HAPLN1,LRIG1,SLC12A6,EDN1,EDN3,EDNRA,CACNG7,CACNG2,ACTL6B,BRD8,KCNMB4,GRIK1,GUCY1A2,GUCY1A1,GUCY1B1,HBA1,MYLK2,KCNC1,KCNC2,KCNMA1,MYL3,NOS1,NPPA,NPR2,HCN1,NUMA1,KCNK10,PDCD2,PDE1C,PDE2A,PDE3A,CDK14,PHKG1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PTPA,PRKACB,PRKCB,PRKCG,MAPK3,RYR1,RYR3,SLC6A7,SLC9A5,SLC12A4,MLC1,ACTR6,PIK3R5,SCG2" Drug 6724_DN Digoxin [20830-75-5]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ASIC1,CDC7,MRTFA,APBB2,SHROOM2,CDC14B,RGS20,ATM,SYNJ2,LRRFIP1,ZFYVE9,SMARCAL1,APPL1,DCAF4,SNPH,RIMS3,ZBTB24,RHOBTB1,SACS,CAMSAP1,FAM49B,CGREF1,ZNF44,GPER1,GUCY1B1,KIF5C,ZNF862,PDCD2,PTPRE,RAB3A,PID1,SH3TC2,ZC3H14,MAP6D1,SUPT20H,ZNF365,FAM214B,ZNF667,MYH15,ZNF415,SPATA7,GLT8D1,CEP68,ARHGEF9,FAM208A,GPR161,TK2,CABIN1,METTL3,SMUG1,SYNC,ZNF248,TIGD6" Drug 6236_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ADCY6,ALDH7A1,MPDZ,SYNJ2,CACNA1I,CAMK2B,ARHGAP33,CREM,DZIP3,KIAA0513,EIF4G2,PLEKHO1,COQ7,F3,EFEMP1,FECH,KIAA1109,EFCAB2,NCKAP1,MSL3,PCSK1N,FERMT2,NR3C1,INPP5B,KCNK1,KCNMA1,MDM4,KITLG,AFF1,ZNF862,NF1,CNOT4,CCSER2,STRN3,MED1,SAMD9,PTN,RALGDS,PNMA8A,ATXN1,SH3BP2,ITSN1,SNAP25,PALLD,ZCCHC24,VPS13A,PLCB1,MTCL1,TCF12,PCDHGA1,ARHGEF12,TRIO,KAT6A" Drug 3803_DN Flutamide [13311-84-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ADCY2,APP,IL33,CANX,ARHGAP33,CLCN4,IFFO1,CSF1,EDRF1,CTIF,MFAP3L,EXOG,ATN1,DTNA,EDIL3,LRRC23,NCALD,FGF1,SEMA4D,TRAF3IP2,GNG3,EML4,SHISAL1,LIFR,MATN3,TM6SF1,SCAMP5,ADAM22,CNOT4,ODF2,PIK3R1,STRN3,ZCWPW1,RGS7,TMEM206,RXRA,ASAP3,SLC1A7,FAM214B,BTBD7,SNCA,WDTC1,ZHX3,ZEB1,RPGRIP1L,TMPO,TNS1,TRIO,ZMYND8,ZNF24,REEP1,EPM2A,SENP7" Drug 1665_UP 2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ASPHD1,PPFIA3,ALDH7A1,BMP7,RAB29,SYNGR3,ARHGEF2,MAGI1,ABCG1,PDE4DIP,LYPD1,SPOCK3,ATN1,RCAN1,EFNA3,EFNB3,EGFR,MBNL2,EIF4G2,HSD17B14,ZNF589,FER,BAIAP2,FHL1,FYN,SYT17,STON1,RASSF8,KIF5C,MAPT,CNOT4,PDPK1,RETREG2,FA2H,PRPH,PTCH1,SUSD4,KCTD17,CCDC25,MAP6D1,CLIP1,ZNF821,ASAP3,LIMCH1,ZCCHC24,KAZN,TRIM2,CRTC1,BEX4,RBFOX2,VGF,REEP1,MAP3K12" Drug 6399_DN C75; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ASIC1,ADCY6,ADORA2A,PKP4,APLP1,CDC14B,PDE8B,BCHE,RAB28,CLCN4,DAPK3,DSCAM,ABCC9,EFNA3,FECH,FGFR1,CGREF1,FYB1,DENND2A,ERAP1,SRCAP,RND1,GPM6A,KIF3A,PADI2,ARHGAP19,KLF12,LAMA2,MMP16,CNOT4,NPR2,CLDN11,PENK,EPN1,SMIM7,CDIP1,PID1,GAL3ST4,RGS10,CSRNP3,ASAP3,SLC4A3,KBTBD4,ZNF667,TK2,CABIN1,TNS1,SMUG1,ZMYND8,HIRA,PLPPR2,VGF,ZBTB14" Drug 6837_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ADRA1D,AP2A2,SEMA6A,ALCAM,CDC42BPA,APC,CDC14B,CDK10,ALDH4A1,ATM,CFLAR,SYNJ2,CAMK2G,B4GALT6,ENTPD4,SOCS5,FAM169A,GREB1,RIMS2,TOM1,CNNM1,SORBS3,ZNF589,FGFR1,GAA,GLS,POLL,GNG4,NR3C1,JAK2,PCBP3,PC,PDE3B,TNPO2,PTPN13,GSTCD,SMTN,SLC9A5,COA1,SNCA,TTBK2,SEMA4A,TCF7,TCF7L2,TRIM2,CRTC1,AHCYL2,PARD3,ZMYND8,PLPPR2,VAV1,GDPD5,EPM2A" Drug 7549_DN CP-944629 [668990-94-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ACLY,ANK3,MARCH3,FUBP1,MTMR2,CANX,SPAG9,ARHGEF2,DNAJB5,QKI,HOMER3,PHF14,SPOCK3,G3BP2,RCAN1,EDIL3,EGFR,RGS17,ETV1,VPS26C,TESK2,FGFR1,ANKFY1,DENND2A,ERAP1,GART,GLYR1,GNAS,EML4,ATXN2L,INPP5B,MBNL1,MYO6,GON4L,PTHLH,TTLL7,NEK11,CLIP1,ZFP30,TNIK,EPB41L3,NXT2,ZEB1,DOCK9,TPD52,CLDND1,XRCC4,ZNF711,HPS4,MVB12B,EPM2A,FZD3,RNF146" Drug 6022_DN Harmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "TRMT9B,AMH,APBB2,PPFIA3,ASPH,NCOA1,EIF4G3,ADAM23,MPDZ,ARHGEF7,BTRC,CA12,ADGRG1,VAX2,NIPBL,BAG4,CNTNAP2,DZIP3,MFAP3L,RABGAP1L,EFNA3,PLEKHO1,DENND4A,ZNF589,FGF12,FHL1,FYN,GLS,POLL,GPR37,HSF2,IL6R,INPP5B,MPP2,OCRL,LRP12,PPM1B,SAMD9,RAD51D,RNASEL,ITSN1,AMBRA1,FBXO11,SHANK2,CXXC4,RCOR3,ZHX3,LHPP,TMEM121,TMOD1,DNAJC12,PLPPR2,VLDLR" Drug 6024_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "RALGAPA1,ALCAM,APBB2,MARCH3,CFLAR,ARHGEF2,SEPT7,TAOK2,SLIT2,RCHY1,CSF1,GPRASP1,ZNF337,DAPK3,RABGAP1L,DTNA,HIPK3,CDKL3,SCML2,ZNF589,C1orf61,GLYR1,GNG4,NR3C1,SLC2A6,KCNN2,IPO5,LIG4,MIA2,MMP16,ADAM22,NUMA1,PPP3CC,PRKAR1B,RAB3IL1,CEP97,RAD52,TCP11L1,ZNF821,SUPT20H,PPP1R9A,ABLIM3,WDTC1,EMC1,PLCB1,EXOC7,IQCE,PSD3,PCDHA5,FRYL,AHCYL2,VGF,GDPD5" Drug 6839_DN Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "RALGAPA1,AK2,ATM,CFLAR,CACNA1D,FOXN3,PLEKHB1,VAX2,ABCG1,FAM169A,CTH,ARHGEF4,RIMS2,DCTN1,EFNA3,RBM12,PHF20L1,KAT8,FECH,SEMA4D,TXNL4A,ATXN2L,KCNJ3,MEIS1,ADAM22,NF1,SMOX,PLXNB1,MINDY2,PTPN13,RAB5B,RBBP6,RGS12,SEC61A2,SEC14L1,NUBPL,EPN2,BTBD7,TMCC1,EMC1,KDM4C,POGZ,ITPRID2,THSD1,PLCB1,TCF7L2,TRIM2,CHST8,KCTD2,TPD52,GDPD5,MPPE1,MARCH8" Drug 2840_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "PLA2G6,ALCAM,MRTFA,APBB2,APC,APOC1,CDC14B,ATM,CFLAR,GYG2,NEURL1,PICK1,CTNND2,NOS1AP,ATN1,SIDT2,SH3GLB1,CELSR3,NCALD,FGFR1,BAIAP2,HPCAL4,OGA,GAB1,MSL3,SLC2A6,MID1,MITF,AFDN,ZNF862,NF1,NPY,NTRK2,PIK3CD,MINDY2,PRKAR1B,PTHLH,PTN,SEC14L1,RASA3,COA1,SMARCD3,LIMCH1,UNC5B,JMJD6,PDLIM2,ZMYND8,VGF,MKRN3,PRDM2,EVI5,ITM2C,MPPE1" Drug 3861_UP Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "ASIC2,ADD2,ALK,TRMT9B,KCNAB2,SEMA4G,BRINP2,STX16,CACNA1G,CACNA1D,ADGRG1,ZFYVE9,CLCN4,TPP1,CNTFR,MICAL2,EDRF1,DAPK3,CTIF,ATN1,C3orf18,VPS13B,SPEG,CORO2B,KIAA1109,CAMSAP1,CAMKK2,NEU3,GCNT2,SRCAP,RND1,GLYR1,HTATSF1,PRUNE2,CELF3,HLF,LSS,MARK1,AFDN,MMP17,NF1,CDK14,MAPK8,RASGRF1,MRAS,FAIM2,ZC3H13,ABCC8,POPDC3,ATP11A,WASHC4,PDIA2,RNF146" Drug 3890_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.56E-05 7.67E-01 2.37E-04 2.70E-03 53 191 "SLC12A5,AP2A2,MRTFA,DOC2A,KCNAB2,GAS7,SYNJ2,CBFA2T2,VAX2,NECTIN3,SH2B1,PDE4DIP,CTNND2,RIMS2,PPP6R2,MAML1,DAPK3,DBN1,ATN1,HIPK3,EGFR,PLXNC1,ING4,COQ7,NCALD,FHL1,DPYSL4,TPK1,GCNT2,SRCAP,TXNL4A,GLS,POLL,DIDO1,MAP2,TM6SF1,NEK1,NF1,PLCD1,PLEC,LRP12,PEX5,CEP97,SLC22A4,ERC1,ARHGAP26,IQSEC2,PLCB1,SMG6,TCF7L2,AHCYL2,SLC44A1,TMOD1" Drug CID000013245 AC1MMLID Stitch 1.59E-05 7.78E-01 2.41E-04 2.74E-03 31 92 "SLC24A4,ATP1A1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALB1,CALM1,KRIT1,SLC24A2,CRMP1,DCT,DLG3,DLG4,EDN1,EIF4G2,ATP2C1,HPS5,SLC11A2,FXYD1,PPP3CA,PPP3CC,RYR1,SLC6A11,SLC8A2,SLC8A1,SLC8A3,SYT1,GPR161,CABIN1,SLC17A7" Drug 2678_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.59E-05 7.79E-01 2.41E-04 2.74E-03 50 177 "AMPD3,PPP4R4,DNAH17,ATP6V0A1,BTRC,CFAP410,CLCN4,CREM,SIPA1L1,PDE4DIP,KIAA0513,DGKG,HIPK3,FAM13A,MBNL2,VPS13B,FER,PRKAG2,CAP2,PDLIM5,GALC,GLYR1,LILRA2,GRIK5,GRIN1,GSN,ATXN2L,IL6ST,SCAMP5,MOBP,KCNK10,PDE4B,CCSER2,PMP22,MBOAT7,PRKACB,PTPRN2,GSTCD,HSPA4L,RPH3A,SLC15A2,DNMBP,AHCYL2,TRPS1,VGF,ZBTB38,PRDM10,KCNAB1,FZD3,FXR1" Drug 3116_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "KIDINS220,BIN1,SEMA4G,RASL11B,CCDC181,AZGP1,NRP2,KSR1,BMP7,FUBP1,CACNG1,CALB2,THSD7A,CAPN3,REPS2,STOML1,SLC4A8,ABI3BP,CPS1,PDE4DIP,EDRF1,SPOCK3,CDON,ATN1,CELSR3,F5,FOXF2,ATF7,GRM7,GRM8,SCIN,KIFC3,MAPT,TAGLN3,NFIX,SLC11A2,NTRK2,PHKG1,TTLL7,PEX26,ZSWIM8,TSPYL2,SPART,SMG6,TRIM2,SZT2,THRA,LILRA4,TRPC1,FAM155A,PLPPR2,XRCC4,SPHK2,ADAMTSL3" Drug 4218_DN Pregnenolone [145-13-1]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "MTUS1,PLA2G6,BIN1,ANK3,APBB2,ARRB2,ST3GAL5,KYAT1,CLCN3,WHRN,BAG4,PPP6R2,DBT,PLPPR4,CHRDL1,EXOG,DYNC1I1,FCF1,EFNA3,PLXNC1,ZNF391,ETV1,SORBS1,GLRB,KLF12,DIPK1A,MEF2C,MTR,NDP,CCSER2,RC3H2,LRP12,APTX,PTN,TMEM231,SCG5,FNDC3A,LIMCH1,TMCC1,RBM34,TNIK,SAMSN1,THSD1,VAMP1,ARHGEF12,AHCYL2,ZNF34,SMUG1,SSBP2,VGF,LMF1,WIPF1,XRCC4,HPS4" Drug 2740_DN Pyrithyldione [77-04-3]; Down 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABHD6,GRAMD1B,MTUS1,PLA2G6,FUBP1,CACNB2,HIP1R,FOXN3,NMT2,QKI,CLOCK,PDE4DIP,RUBCN,DGKG,SMG7,CNNM1,SIDT2,EFNA3,EGR3,ING4,TUBD1,PTK2B,FHL1,TRMO,PDLIM5,INPP5K,COPS8,LILRA2,PADI2,ATXN2L,ITGAM,MAP4,OLR1,PIK3R1,CCSER2,NLE1,SLC25A23,MINDY2,RAB3A,ZNF821,SCG5,DOCK10,CCDC88A,ZKSCAN3,PLCB1,ATP11A,KIAA1107,TCF7L2,CRTC1,ZNF34,TPM3,TRPS1,ZMYND8,ZNF225" Drug 2493_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABR,NDRG2,GRAMD1B,MRTFA,KCNAB2,APC,ARRB1,NCOA1,BACH1,SYNJ1,MTMR2,SLC25A14,CD86,RAB33A,ARMC8,CHD1L,VCAN,DGKG,DBT,RCAN1,DTNA,HIPK3,SIDT2,COQ7,CD320,F5,KAT8,FHL1,GABRA2,POLL,ATXN2L,IL6R,KIF2A,MEF2C,N6AMT1,NF1,NUMA1,PSMD13,PTPRN2,RNASEL,MYH14,PLPPR3,SEC14L1,MRAS,EPN2,SLC11A1,DOK5,SS18,CEP68,ADGRL3,TCF4,FLRT2,XRCC4,PHTF2" Drug 4987_DN Khellin [82-02-0]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "SOCS6,B4GALT6,PLAA,CLU,TPP1,CNTNAP2,ARMCX2,JAKMIP2,SGSM2,RABGAP1L,ATN1,RCAN1,HIPK3,SORBS3,FER,FGFR1,EFCAB2,GABRA2,INPP5K,MALT1,RAB30,POLL,GRIK5,ATXN2L,HNMT,ICA1,KCNN2,VWA5A,KITLG,NF1,PLCD1,MED1,MAPK7,SAMD9,TMEM104,RGS10,ROM1,ZNF821,RASA3,PREX2,PEX26,FAM214B,LIMCH1,UNC5B,LHPP,EXOC7,IQCE,DICER1,SLC44A1,TMOD1,MICAL1,KAT6A,NUP214,SSPN" Drug 2877_UP DO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ALK,FAM131A,RGS20,PLA2G4C,DNAH17,RGS11,CFLAR,BAIAP3,CDK5R2,CBFA2T2,FOXN3,CHRNA4,PICK1,PLCH2,SPOCK2,DNAJC6,SRGAP3,HSD17B14,EPHB1,ERBB2,F5,FOXG1,KHDRBS3,NSG1,GAP43,HPGDS,SOX21,IRF8,MID1,NNAT,P2RY1,PCSK1,PFKFB2,PURG,LRP12,CEP41,VPS13C,ZNF493,RPS6KA2,ASAP3,SLC9A5,WDTC1,ZNF423,ASTN2,SLC19A3,DAAM2,R3HDM1,TNS1,PDIA2,FLRT2,ZFP37,SYNC,KCNAB1,MVB12B" Drug 3834_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ALDH4A1,KIF1A,ADAM15,TAOK2,ZFYVE9,DAPK3,MFAP3L,EFNA3,EGFR,SORBS3,ELN,HSD17B14,VPS13B,CDKL3,F3,KIAA1109,FGFR1,CGREF1,GAB1,SRCAP,GFER,GLYR1,GPD2,STON1,HNMT,ICA1,LSS,MBD1,KITLG,ZNF862,NEK1,NF1,NFYA,PLCD1,LRP12,MED1,PTHLH,ZSCAN32,RAD52,ATG16L1,FERMT1,ASAP3,FUZ,SLC1A7,SLC6A8,SNCA,PLCB1,SYN2,ATP11A,KIAA1107,TCF7L2,LAT2,REEP1,PHTF2" Drug 7479_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADD2,KIDINS220,NME5,BIN1,APBA2,MARK4,SYNJ1,SCAPER,CACNA1D,USP2,FOXN3,TPP1,PICK1,AKAP12,SDC3,SEC14L5,CTIF,MYEF2,ATN1,EDN1,ENO2,EPB41L1,DPYSL4,OGA,SYT17,DISC1,SRCAP,RAB30,GPER1,GRM1,ITPKB,KCNQ3,MAP4,MPP2,NCAM2,CNOT4,PDE4A,NLE1,PLXNB1,WDR25,ZSCAN32,PAQR6,SH3BP2,FAM214B,SLC11A1,SLC20A2,ZHX3,WSCD1,CRTC1,DICER1,TRIO,XRCC4,PRDM2,STMN4" Drug 5540_DN Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ATM,ADAM23,CFLAR,CDK5R1,BAIAP3,ARHGAP33,B4GALT6,PLAA,FAM189A2,AKAP7,CSNK1E,KIAA0513,GIT2,SMG7,DPH1,MAMLD1,EFNA3,TNK2,EML1,EPB41L2,DLC1,FGFR1,FHL1,NOP56,CINP,PDLIM5,CNTRL,MAP4K5,KCNJ3,LMO2,MIA2,MSI1,ADAM22,NEK1,PDE3B,PRKAR1B,MAPK7,MAPK8,RGS10,ZNF821,PPP4R3A,BTBD7,SNCA,POPDC3,SEMA4A,PJA1,EXOC7,FBXW11,PSD3,AP4E1,PIK3R5,HIRA,FTSJ1,AAAS" Drug 1821_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "APOC1,PPFIA3,CDK10,MARK4,SRSF11,CNOT8,SLC4A7,CSF1,DZIP3,ZFYVE16,ZNF337,SGSM2,SORBS3,SCML2,BAIAP2,CINP,CGREF1,INPP5K,GART,SRCAP,DIDO1,GUCY1B1,SHISAL1,KIF2A,KIFC3,MITF,GIT1,ZNF862,PDE1C,FA2H,MED1,PPP3CC,SAMD9,PTPN13,NUDT11,MCMBP,MAPK12,LIMS2,SMARCC2,ZBTB43,STX1A,VPS13A,EXOC7,DNMBP,TCF4,TCF7L2,ZEB1,CABIN1,LMF1,ZNF32,MAP3K12,PRDM2,HPS4,PHTF2" Drug 4472_DN Estropipate [7280-37-7]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "APOC1,SEMA4G,ARRB2,PDE8B,SYNJ2,SYNGR3,CACNA2D2,CHM,HAPLN1,AATK,CSF1R,VCAN,SNPH,PLXNC1,ING4,STX2,KIAA1109,SORBS1,CINP,FYB1,GABRA2,GAD2,SYT17,STON1,LSS,MPP2,NFIX,NPR2,ODF2,PBX1,PPP5C,MAPK8,RAB3IL1,RAD51D,ZCWPW1,GAL3ST4,KIRREL1,NEK11,RPS6KA2,BCAN,SLC9A5,BTBD7,BEX1,DDN,MAPK8IP3,MLC1,WWC1,RPGRIP1L,CRTC1,TEX15,BHLHB9,R3HDM1,ZNF24,TIGD6" Drug 3700_UP Merbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "KIDINS220,ANK1,ARHGDIG,ATP1A3,CADM3,N4BP2L1,BMP7,USP2,CHI3L2,NRXN3,CTNND2,BRINP1,SORBS3,RASGRP2,MTSS1L,CORO2B,SEMA4D,ZNF44,GNAL,GNAS,MCHR1,GRIK2,GRIN1,GRM1,GRM8,C2orf72,IGSF1,KCNQ3,KIF5A,MEF2C,AFDN,MYH3,NEUROD1,SLC11A2,PCDH9,CAMKV,MTRF1L,MAPK8,ZSCAN32,RASGRF1,RGS4,PKNOX2,SNCA,SYN2,ADGRL3,PCDHGA10,RIMBP2,TNS1,TPM1,TRIO,VIPR2,TFIP11,EPM2A,NUP214" Drug 7367_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "AP2A2,BIN1,CDK13,SYNJ2,NIPBL,SH2B1,CSNK1E,SLITRK5,DZIP3,EDNRA,ENO2,STX2,VPS26C,ST3GAL6,IQCG,TRMO,TACC2,CINP,GART,COPS8,NR3C1,AGBL5,AGFG1,DIPK1A,MITF,NF1,SLC11A2,SETD4,PDE1C,PLCD1,PEX5,RGS3,RGS10,TTLL7,NUDT11,SUGCT,SBF1,SH3GL3,AMBRA1,NUBPL,FAM214B,KBTBD4,SLC22A4,ZKSCAN3,DOP1A,ATP11A,ANKRD12,TCF4,LMF1,ZNF189,MAP3K12,NT5M,ST7,PHTF2" Drug 6483_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADRA1D,AK2,SEMA6A,AMH,CDC42BPA,APC,FAM131A,DNAH17,MARK4,ATM,BAIAP3,BTRC,CAMK2B,SCARB1,CRY2,GREB1,HP1BP3,EDNRA,EN2,FAM49B,OGA,GCNT2,POLL,PRUNE2,INPP5B,P2RY1,POLG,PTN,ZSCAN32,PTPRO,KHDRBS2,RGS10,ATXN2,ZNF821,NLGN1,SLC9A5,INTS9,WDTC1,DOK5,ZHX3,IQSEC2,SS18,MAPK8IP3,ARC,EXOC7,TRIM2,TNS2,AHCYL2,ZMYND8,ZKSCAN5,HIRA,KCNK12,ZNF74,PRDM2" Drug 4276_DN Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ACTN2,AP2A2,CNTNAP1,CDK10,PPP4R4,RASL11B,KIF1A,SYNJ2,MYRF,BAIAP3,CFAP410,ZFYVE9,AKAP7,WHRN,SH2B1,CRMP1,CSNK1E,DZIP3,GIT2,SPOCK3,RGS17,HPCAL4,FLT1,CSPG5,INPP5K,SRCAP,POLL,FERMT2,ATXN2L,SHISAL1,INPP5B,KCNMA1,MAP4,MAPT,MEIS1,MIA2,LYRM9,ZNF862,PALM,PLXNB1,FAM120C,ASAP3,DOCK10,ZNF667,ZHX3,IQSEC2,ARHGEF12,DNAH7,CABIN1,VGF,VIPR2,SEMA3B,MPPE1,SENP7" Drug 2441_DN Amphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ARID1A,KIDINS220,BIN1,APP,MARK4,SCARB1,CLCN4,STOML1,ABCG1,VCAN,PPP6R2,DGKG,SPATA2,CNNM1,SIDT2,EFNA3,EFNB3,PLEKHA1,FHL1,FOXG1,AGAP2,SEMA4D,ERAP1,INPP5K,LILRA2,NCKAP1L,LSS,GIT1,NCAM1,CNOT4,NPR2,PLCB2,SLC25A23,PRKAR1B,MAPK10,CNNM2,CNTLN,FAM184A,ZCWPW1,MRAS,SCG5,SH3BP2,FAM102A,SMTN,FAM214B,SLC11A1,KDM4B,DBNDD2,TROVE2,ARHGEF9,TCF7L2,OBSL1,KAT6B,UBE3B" Drug 4956_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADCY6,AP2A2,AK2,ALAD,APP,ASPH,BCL7A,MTMR2,BTRC,CBR1,SYNGR3,CLU,VAX2,QKI,PDE4DIP,PPP6R2,JAKMIP2,HP1BP3,RABGAP1L,DTNA,EFNA3,SORBS3,IRAK4,RGS17,ENO2,DPYSL4,JAK2,KCNK1,MBD1,MEIS1,NEK1,PLCD1,PLEC,POLG,MAPK3,BSDC1,NEK11,ZNF365,ELMO2,BTBD7,SMARCA4,ZBTB43,STX1A,ASTN2,EXOC7,CAMSAP2,WWC1,TCF7L2,TRIM2,TMPO,KAT6B,TRIO,LMF1,FTSJ1" Drug 6038_DN Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABHD6,AP2A2,ALCAM,LTBP4,BIN1,APC,PPFIA3,CDC14B,ARHGDIG,ADAM15,CACNA1I,CBFA2T2,TAOK2,HOMER3,CREM,CSF1,FEZ1,PDE4DIP,GPRASP1,DCAF8,SGSM2,DNM2,EIF5,ERBB2,F3,KAT8,FHL1,SEMA4D,GLS,ADAM22,CNOT4,NUMA1,SERPINE2,CCSER2,PRKAR1B,PRPH,CEP97,RNASEL,SEC14L1,ZNF821,ITSN1,COA1,FCHO1,TACC1,IQCE,TPD52,NPL,ZMYND8,VGF,LMF1,XRCC4,ZNF74,GDPD5,HPS4" Drug 4600_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADRA1D,PLA2G6,LTBP4,GAS7,BCAS1,CFLAR,CACNA1I,CFAP410,MAP7,ARHGEF2,LARGE1,RAB28,CLCN4,CREM,ABCG1,PDE4DIP,CNTNAP2,CTIF,C2CD2L,DMPK,TENM1,ING4,DLC1,KIAA1109,GABRA2,GAD2,GPD2,CNTRL,KLF12,AFF1,NF1,PALM,PCDH9,RAB3IL1,ENOX1,FBXW7,ST6GAL1,SLC15A2,SNCA,KDM4B,TSNAXIP1,UNC5B,ARHGAP26,RBM26,RAP1GAP2,HIF3A,RIMBP2,TNS1,CDK20,TPM3,ZNF711,REEP1,SLC17A7,KCNAB1" Drug 4693_UP Kawain [500-64-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABHD6,ALCAM,AMPD3,CDC42BPA,SEMA7A,PLA2G4C,BRINP2,CFLAR,ST3GAL5,CHRNA4,ZFYVE9,FADS2,CNN3,CREM,SIPA1L1,GIT2,SRGAP3,EXOG,ST8SIA3,EDN1,RASGRP2,ZNF589,KIAA1109,FHL1,OGA,TXNL4A,GLYR1,GPM6B,GPER1,KITLG,ADAM22,BCO1,OPCML,P2RY1,PFKFB2,SERPINI1,STRN3,ZSCAN2,C1orf54,RFX2,ASAP3,SMARCD3,KDM4B,PHLDB1,DMXL2,TCF7L2,PCDHA6,RUNDC3B,ZNF24,SLC30A3,PRDM2,NAV2,MVB12B,AP3B2" Drug 2290_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "APC,GAS7,MTMR2,CACNA1I,CACNA1G,CFAP410,SULT4A1,HOMER3,CPS1,CREM,CRMP1,RIMS3,DAPK1,MBNL2,EIF4G2,ELAVL3,ERCC2,PIPOX,TUBB4A,KIAA1109,HPGDS,PRUNE2,GPER1,KCNMA1,KIF5A,MAN2A2,MAP4,PALM,PFKFB2,TNPO2,GDPD2,PTAFR,PTHLH,TRIM68,RFX3,TMEM206,RYR1,SEMA6D,ASIC4,ST6GAL1,SNAP25,DOP1A,ARHGAP26,SPART,ATP10B,AJAP1,EXOC7,ZEB1,HEY2,TNS1,PIK3R5,TRPM2,FLRT2,VAV2" Drug 6035_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ASIC1,KCNAB2,APC,CDC14B,ASPH,ST3GAL5,CACNA1I,CFAP410,CBFA2T2,ARHGEF2,SEPT7,TAOK2,AKAP7,CSF1,GREB1,JAKMIP2,MFAP3L,TMCC2,CDON,HIPK3,CNNM1,EN2,COQ7,DMTN,FHL1,PDLIM5,GAB1,TXNL4A,GLYR1,RAB30,GLS,POLL,SMAD1,MAP4,GIT1,ADAM22,PC,SERPINE2,SMIM7,PRODH,PRPH,GON4L,TMEM104,CEP97,ZFHX4,WLS,ZNF821,CEP68,VAMP1,EXOC7,TCF7L2,PCDHA5,TK2,SSPN" Drug 4675_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "MTUS1,AGT,ALAD,ALDH7A1,CACNA1G,CAST,SYNGR3,CRLF1,FOXN3,TAOK2,CLCN4,AKAP7,TCEAL2,NRG2,SH2B1,AATK,SMG7,RABGAP1L,DTNA,EDNRA,CNNM1,SIDT2,EFNA3,MRNIP,RGS17,EN2,DMTN,PNMA2,ZNF44,TRAF3IP2,IFI16,IGFBP1,KIF5C,TM6SF1,NEUROD1,NF1,PIK3R1,ZSCAN32,PTPRB,RAB3IL1,GSTCD,ATXN7,FRMPD1,TSNAXIP1,SOX15,WWC1,HIRA,LMF1,WIPF1,TFIP11,PRDM2,KCNAB1,PHTF2,TIGD6" Drug 7432_UP Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "LTBP4,PPFIA3,ARHGDIG,ALDH4A1,CFLAR,CDK5R1,ST3GAL5,CACNA1D,NECTIN3,FEZ1,PDE4DIP,EDRF1,ZFYVE16,GIT2,ARMCX2,FBXL5,COQ7,DENND4A,VPS26C,SEMA4D,GALC,SRCAP,POLL,GRB10,GRIK5,NR3C1,RNFT2,ARHGAP19,ATXN2L,MAP4,ADAM22,SLC11A2,SERPINE2,CCSER2,KCTD15,NLE1,PLCD1,MBOAT7,MED1,PTCH1,ZSCAN32,RIPOR1,WLS,SMTN,TMCC1,WDTC1,PLCB1,EXOC7,HEY1,TRIO,TRPC1,VLDLR,MAP3K12,MVB12B" Drug 6545_UP PHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "C1QTNF1,KCNAB2,GAS7,SEMA4G,ATM,ADGRB2,CFLAR,MYRF,CFAP410,CCNT1,CBFA2T2,ARHGEF2,FADS2,NIPBL,SH2B1,SDC3,FAM131B,EDIL3,HIPK3,FEM1B,SORBS3,TNK2,EPB41L2,COQ7,ETV1,FGFR1,FOXG1,PRELID3A,ATP8A2,GCNT2,GFER,HTATSF1,GUCY1B1,SCIN,JAK2,NFYA,CNOT4,PDGFRA,PMS2,GON4L,ZNF671,FNDC3A,CDK5RAP2,ZHX3,KDM4C,JMJD6,EXOC7,WWC1,TBCEL,FBXW11,MICAL1,TFIP11,EMSY,MPPE1" Drug 3536_DN Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "BEGAIN,AMPD3,KCNAB2,CDC14B,RASL11B,ALDH4A1,CFLAR,CAMK2G,LHX2,RAB28,IQCK,LRIG1,RIMS3,RUSC2,KBTBD11,TSPAN5,EDNRA,EFNA3,EFNB3,CELSR3,SORBS3,NCALD,ANKMY1,FER,FGFR3,SCARA3,FLNC,DPYSL4,GAD1,DISC1,TDRKH,MUM1,INPP5B,KCNH2,IPO5,NNAT,NPR2,PALM,SERPINE2,RETREG1,POLG,PRODH,RGS12,SEMA6D,ITSN1,ASAP3,PHLDB1,AJAP1,VPS13A,ROBO3,TMEM121,ZNF34,TPD52,WNK1" Drug 2776_DN Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABHD6,AMPD2,APBB2,PPFIA3,APP,BCL7A,BTRC,CBFA2T2,PLEKHB1,FAM189A2,SIPA1L1,PPP6R2,EDRF1,MFAP3L,CNNM1,SIDT2,ABI2,CDKL3,F8,ZNF589,DISC1,GNG4,HNMT,DHX35,HSD17B1,KCNN1,MEIS2,LYRM9,ZNF862,CNOT4,NPR2,PDE4A,PLEC,PTPRE,ZSCAN2,RGS10,TCP11L1,PEX26,SLC6A8,SHANK2,ZKSCAN3,EMC1,TSPYL2,INKA2,MAPK8IP3,STX1A,VPS13A,ATP11A,EXOC7,KIAA1107,RPGRIP1L,PLPPR2,MAP3K12,MPPE1" Drug 4596_UP Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "DPF1,RALGAPA1,PLA2G6,LTBP4,CADM3,KSR1,BMP7,BAIAP3,CACNA2D2,STOML1,CDC42BPB,CREM,CRY2,ABCG1,CNTNAP2,ARHGEF4,NOS1AP,SNPH,SPOCK2,C2CD2L,SPOCK3,FGFR1,SEMA4D,ZNF44,RUNDC3A,CACFD1,ATXN2L,HSD17B1,GIT1,NELL2,NOVA2,CAMKV,SPATA6,POLG,SNRK,PTN,PTPRO,CCDC40,RALGDS,RGS10,KCTD17,FBXW7,MAPK12,DOCK10,SLC2A5,SLN,ARHGEF9,EXOC7,PCDHA5,TEX15,GPR161,WNT7A,KCNK12,KCNAB1" Drug 5742_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ABAT,ADORA1,AGT,MRTFA,SEMA7A,ASTN1,CADM3,ADAM23,GYG2,NEURL1,PLEKHB1,CREM,CRMP1,HEPH,EXOG,ABCC9,ING4,ELN,ATP8A1,KIAA1109,OLFM1,AGAP2,HBS1L,LYVE1,GSTM5,ELOVL5,ICA1,SHISAL1,ITGA7,ITIH2,MYCN,NPPA,NRCAM,ODF2,PIK3R1,PMP2,PPP5C,ENOX1,EMID1,FRMPD1,CNKSR2,RPH3A,ZSWIM8,LHPP,INKA2,JMJD6,VAMP1,MCF2L,TBCEL,TCF4,TK2,ICAM5,TNS1,PIK3R5" Drug 2833_UP Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "SYN3,ADCY6,LTBP4,AMT,APAF1,APBB2,MARK4,BAIAP3,CACNA2D1,ZMYM4,ASIC3,TCEAL2,CRMP1,ABCG1,NOS1AP,CTIF,C3orf18,HSD17B14,EZH1,FGFR1,BAIAP2,C1orf61,OGA,SRCAP,TDRKH,CACFD1,NR3C1,GSTM5,GUCY1A1,KHK,VWA5A,MAOB,NTRK2,PDE4A,PRKAR1B,MAPK10,GDPD2,SH3BP2,SLC1A7,SMARCC2,SNCA,WDTC1,SOX3,ZCCHC24,ATP10B,ARHGEF9,PLCB1,TCF7L2,DICER1,TGFBR3,TNS1,FAM155A,SPHK2,PRDM2" Drug 6633_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ARID1A,PLA2G6,FAM135A,ALK,MRTFA,APAF1,EPB41L5,GAS7,CDC14B,BRINP2,PROM1,BMP7,DNAJB5,LY86,ENTPD4,RIMS2,USP6NL,SMG7,DLG3,DMPK,DTNA,ZNF391,SPEG,GPM6A,CACFD1,ATXN2L,KLF12,LIFR,VWA5A,PALM,PDE3B,SPATA6,PRPH,PTHLH,PTN,KCNIP1,PEX26,ARHGEF40,SLCO1A2,TNIK,IZUMO4,HECW1,SPTB,CDK19,CEP68,PHLDB1,PLCB1,COBL,MCF2L,PCDHGA10,OBSL1,TNS1,PAK5,CAMK1G" Drug 2667_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADORA2A,TRMT9B,PPFIA4,APBB2,ASPH,NUMB,BACH1,LDLRAD4,TPP1,IQCK,NCOR2,ARHGEF10,CSNK1E,CTH,ARHGAP32,CTIF,SV2A,ELN,KIAA1109,CAMKK2,SEPT9,SPACA9,TJAP1,KCND3,KPNA5,MAP4,MAPT,MGAT3,MYO6,NNAT,OGG1,SERPINE2,SYTL2,PTK2,PEX5,RAB3IL1,KHDRBS2,RPS6KA2,FOXRED2,SCN2B,PPM1E,FRMPD1,SOX2,DDN,SS18,NCDN,RGL1,PLCB1,TCF7L2,NSD1,TPD52,VIPR2,PRDM2,TIGD6" Drug 1545_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "DPF1,NDRG2,KIDINS220,SPARCL1,AMPD3,AMT,APOC1,MARK4,CFLAR,SYNJ2,CBFA2T2,ARHGAP33,CLGN,CACNA2D2,AKAP7,RIMS2,KBTBD11,FRY,EFNB3,ING4,ERCC2,TUBB4A,ZNF589,DPYSL4,RUNDC3A,ATF7,NR3C1,HNMT,C2orf72,KIT,LIG4,AFDN,TNPO2,CEP41,CCDC40,CARF,DOCK10,CNKSR2,SYBU,SLC11A1,SNCA,RBM34,ERC1,SPTB,SYN2,KIAA1107,TRIM2,SZT2,GPR161,TIAM1,TK2,PIK3R5,WIPF1,SENP7" Drug 3256_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ASIC1,ARID1A,LTBP4,PKP4,APBB2,PDXK,PDE8B,MARK4,ASPH,CBFA2T2,DNAJB5,ENTPD4,EDRF1,DCTN1,DNM2,RCAN1,DTNA,PLXNC1,RRAGB,ZNF589,FGFR1,GPER1,ICA1,INPP5B,ZNF862,NF1,NUMA1,PALM,PLCD1,MINDY2,PRKAR1B,MAPK7,PTHLH,RGS12,ZFHX4,SH3BP2,AMBRA1,BTBD7,PDZRN3,EMC1,CAMTA2,TTBK2,TBCEL,RPGRIP1L,OBSL1,AHCYL2,TMOD1,RUNDC3B,UCHL1,VLDLR,ZBTB14,SYNC,WNK1,KAT6A" Drug 5392_UP Metolazone [17560-51-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "CDK13,SCAPER,BTRC,CAMK2G,SLC16A4,ARHGEF1,CBFA2T2,CACNA2D2,B4GALT6,DNAJB5,CREM,INTS1,CTIF,PLXNC1,TENM1,EN2,DMTN,MTSS1L,RRAGB,KIAA1109,FHL1,DISC1,GATM,GLYR1,GLS,POLL,GNG3,PRRC2B,CNTRL,RASSF8,ATXN2L,KCNH2,KCNJ3,MAP4,MARK1,AFF1,MMP17,PCDHGC3,CDK18,PDE3B,GPR85,LRP12,PPP5C,CEP41,ASAP3,FBXO11,SMTN,KIAA1107,KIAA0930,AMOT,SLC13A3,ZIC3,DNALI1,KCNAB1" Drug 2710_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADRA1D,SRPX,ANK2,PPP4R4,NUMB,HIP1R,SCARB1,EPS15L1,CLCN4,IQCK,NRG2,CTH,HDAC9,MFAP3L,RABGAP1L,NR1D2,DTNA,EFNA3,C3orf18,EIF1,RASGRP2,CD320,DLC1,KHDRBS3,CSPG5,COPS8,GPR75,GNG4,GRM1,GRM7,MAP4,MATK,MEF2C,NDUFA5,NNAT,SLC25A23,PTAFR,RAD52,ZFHX4,MAPK12,PPM1E,FAM214B,SLC11A1,ZNF667,RBM26,DDN,TROVE2,KAZN,CRTC1,TK2,PARD3,TNS1,CDK20,SPHK2" Drug 2670_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ACTN2,NR0B1,SYT13,ANK3,ASPH,PTCH2,ATP1A3,AZGP1,CRLF1,DNAJB5,PICK1,COL9A2,HAPLN1,ARHGEF10,HS3ST2,TRAPPC9,DTNB,EDN1,EDN3,EDNRB,ELAVL3,HSD17B14,DMTN,OLFM1,B3GAT1,GAD1,GNAO1,GRK4,SPACA9,KCNH1,KCNQ3,MN1,NCAM1,NINJ2,PDE4D,PHKG1,PPARA,PROX1,PTHLH,RGS4,RGS12,EMID1,ABLIM3,SLC6A9,SLC11A1,BTBD7,PEG10,SMG6,RPGRIP1L,FAM189A1,TIMP4,ICAM5,SEZ6L,SCG2" Drug 2221_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "SEMA6A,SRPX,MRTFA,CADM3,BACH1,CFLAR,SGCE,BAIAP3,BTRC,USP2,SEPT7,CDH2,VCAN,GREB1,RIMS2,NOS1AP,DRD1,ATN1,EDNRA,EFNB3,MBNL2,PLXNC1,NCALD,F5,FGF13,FGFR1,C1orf61,SORBS1,PRELID3A,FYB1,MSL3,GNG3,KLF12,ITPKA,KCNH2,MAN2A2,MMP16,MOBP,OMG,PFKFB2,PLCD1,POU3F4,RAD52,ASAP3,SLC9A5,SLC11A1,ATP10B,AJAP1,PLCB1,SMG6,WSCD1,NT5M,SLC17A7,KAT6A" Drug 2628_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "ADORA2A,ALCAM,SEMA4G,MARK4,RASL11B,CADM3,KSR1,CFAP410,CA4,CCKBR,NEURL1,NRXN3,SULT4A1,NCOR2,LRIG1,MFAP3L,TMCC2,EDN3,EDNRA,PLXNC1,DMTN,STX2,EZH1,ZNF589,GRM1,PTGDR2,ATXN2L,PCBP3,PFKFB2,PIK3CD,NLE1,PLP1,MBOAT7,PRODH,KCTD17,SH3BP2,KANSL3,SLC11A1,SMARCD3,DOP1A,WDTC1,SPTAN1,IQSEC2,COLGALT2,SAMSN1,ST5,WSCD1,TK2,TMOD1,AMACR,TRPM2,VAV2,PRDM2,ADAMTSL3" Drug 6229_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.63E-05 8.00E-01 2.44E-04 2.78E-03 54 196 "AK2,MRTFA,APAF1,GAS7,DGKD,APOC1,PPFIA3,SEMA4G,ATM,SLC4A4,SYNJ2,MTMR2,LDLRAD4,CA12,CACNA1A,ZFYVE9,HOMER3,PDE4DIP,EGFR,ING4,FAM198B,OLFM1,FGFR1,C1orf61,TRAF3IP2,GFER,GLYR1,HTATSF1,MAP4K5,KHK,IPO5,LMO2,ZNF862,NEUROD1,SAMD9,FAM120C,NKAIN1,SBF1,FBXO11,ABLIM3,SLC1A7,SMTN,LIMS2,PDZD2,SPTAN1,TTBK2,ARHGEF9,TAL1,WSCD1,TGFBR3,PIK3R5,DNALI1,MPPE1,SSPN" Drug ctd:C080703 SK&F 83959 CTD 1.63E-05 8.01E-01 2.45E-04 2.78E-03 45 154 "NDRG2,PDXK,CAMK2A,NFS1,SEPT7,CDC42,CLTA,CLTB,ARNT2,DLG4,DPYSL2,DRD1,DNAJB6,SH3GLB1,ENO2,TUBA1B,ATP5PD,CAP2,DPYSL4,GLUL,GNAO1,HNRNPK,IDH3A,STMN1,PCMT1,TMOD2,SEPT4,PSMA6,QDPR,PTGR2,SH3GL2,SIRT2,NAPB,SNCB,STX1A,SEPT3,NSFL1C,SYN2,PHF24,TPM4,TUBB2A,UCHL1,DPYSL5,GOPC,HNRNPA3" Drug CID003016733 1-hydroxypyrazole Stitch 1.64E-05 8.03E-01 2.45E-04 2.79E-03 7 8 "GRIA1,GRIA2,GRIA4,GRM3,SLC1A2,SLC1A3,SYNE1" Drug CID003614351 1-hydroxyimidazole Stitch 1.64E-05 8.03E-01 2.45E-04 2.79E-03 7 8 "GRIA1,GRIA2,GRIA4,GRM3,SLC1A2,SLC1A3,SYNE1" Drug CID000003954 loperamide Stitch 1.66E-05 8.13E-01 2.48E-04 2.82E-03 34 105 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,CACNA2D2,CACNG7,CACNG3,CACNG2,GRIN2C,GRIN2D,HCN1,OPRL1,PENK,ABCB1,PKD1,PRKCB,PRKCG,PKN2,PRKCZ,RYR1,RYR3,SLCO1A2,SST,TAC1,TACR1,TPCN2" Drug CID000016362 pimozide Stitch 1.68E-05 8.22E-01 2.51E-04 2.85E-03 39 127 "ADRA1D,ADRA1B,ADRB2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,KRIT1,CACNA2D2,CHRM1,CALN1,DRD1,DTNA,CACNG7,CACNG3,CACNG2,GPT2,HTR2A,KCNH1,KCNH2,MITF,OPRL1,PKD1,RYR1,RYR3,SOX10,SST,ABCC8,VPS13A,MLST8,TPCN2,TRH" Drug CID000123885 CGP55845 Stitch 1.71E-05 8.38E-01 2.56E-04 2.91E-03 18 41 "ADORA1,ADORA2A,CHRM1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GJB1,GRIK1,GRM1,GRM2,GRM5,GRM8,KCNK3,MAG,PMP22" Drug CID000021218 Aliquat 336 Stitch 1.72E-05 8.43E-01 2.57E-04 2.92E-03 16 34 "CACNA1A,CACNA1B,CNOT8,EPS15L1,DNM1L,FOXO3,GFRA1,GPR37,PACRG,NF1,OPA1,MAPK9,MAPK10,RET,FBXW7,SOX10" Drug CID000005701 XeC compound Stitch 1.75E-05 8.56E-01 2.61E-04 2.97E-03 29 84 "ADCYAP1R1,PLA2G6,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCS1L,CACNA1B,CACNA1E,CACNA2D1,CCK,CD38,NTM,ATP2C1,RAPGEF4,GRIK1,GRM1,GRM2,GRM5,GRM8,ITGAM,NPR2,MAPK3,RYR1,RYR3,TAC1,CABIN1,TRPC1,TRPC3" Drug 5224_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.76E-05 8.61E-01 2.62E-04 2.98E-03 52 187 "C1QTNF3,AMT,SEMA7A,APBB2,CDK13,MARK4,SCAPER,CBFA2T2,RCBTB2,CHM,CHRNA4,PDE4DIP,CTH,HS3ST2,SLC12A6,EDNRA,HEYL,MBNL2,ING4,LRRC23,INPP5K,ALDH1L1,GLYR1,STON1,HNMT,ICA1,KCND3,LMO2,SMAD1,MDM4,ZNF862,NEK1,PFKFB2,SERPINI1,RAB3IL1,ZCWPW1,ZNF493,CARF,PCMTD2,TCP11L1,SH3BGR,ZKSCAN3,WDTC1,TSNAXIP1,CDK19,THSD1,CEP68,RGL1,PCDHA5,RUNDC3B,FLRT2,MARCH8" Drug 3278_DN Naringenine [480-41-1]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.76E-05 8.61E-01 2.62E-04 2.98E-03 52 187 "AP2A2,ALK,GAS7,BCAS1,PPFIA3,APP,MARK4,ATM,CFLAR,SYNJ2,GYG2,CA4,ZFYVE9,NMT2,SLC4A7,CSF1R,DTNA,FCF1,OPTN,IRAK4,FHL1,FOXG1,C1orf61,EFCAB2,OGA,ARFIP1,SPACA9,NR3C1,GSN,ATXN2L,TJAP1,KCNJ3,KITLG,LYRM9,NFYA,PCDH9,PDE3B,PIK3R1,PMS2,PRKAR1B,RGS12,ZCCHC24,KDM4C,POGZ,DIP2A,STX1A,PSD3,TNS2,TRIO,REEP1,WNK1,KCNAB1" Drug 5233_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.76E-05 8.61E-01 2.62E-04 2.98E-03 52 187 "RALGAPA1,PLA2G6,SPARCL1,APBB2,N4BP2L1,SYNJ1,REPS2,ARHGAP33,TCEAL2,DZIP3,GREB1,ATN1,SIDT2,MBNL2,ING4,MRNIP,HSD17B14,PTK2B,GLS,POLL,STON1,GPER1,PCLO,GUCY1A2,TJAP1,LMO2,LYRM9,ZNF862,NF1,SERPINI1,PLCD1,SNRK,PTCH1,RALGDS,RGS10,CARF,PCMTD2,TCP11L1,ASIC4,UHRF1BP1L,SPTB,IQSEC2,CEP68,PHLDB1,ARHGEF9,TACC1,PCDHGA10,THRA,PARD3,XRCC4,SCG2,MARCH8" Drug 7368_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.76E-05 8.61E-01 2.62E-04 2.98E-03 52 187 "APBB1,EPB41L5,SEMA4G,MADD,PDE8B,C5,MAP7,CHRNB2,PLAA,PCYT1B,WHRN,CNTNAP2,SDC3,CTH,ARNT2,EXOG,DSCAM,EFNA3,EIF5,TESK2,FOXF2,OGA,ALDH1L1,GCNT2,GPER1,GRM8,SHISAL1,TJAP1,KIT,TAGLN3,NDP,NF1,NUMA1,CLDN11,KCTD15,SMOX,TNPO2,PPARA,PRKAR1B,CNNM2,SYTL2,PTHLH,FBXW7,SPTAN1,PHLDB1,PSD3,CRTC1,TF,TK2,R3HDM1,TNS1,WIPF1" Drug 5258_UP Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.76E-05 8.61E-01 2.62E-04 2.98E-03 52 187 "AP2A2,APBA2,CDK13,ASPH,KSR1,CACNA2D1,CACNG1,CLGN,CACNA2D2,B4GALT6,CLCN4,AKAP6,CRMP1,CSF1,SDC3,ATN1,SIDT2,CALCRL,NRN1,PTK2B,CAMSAP1,SCARA3,HPCAL4,SORBS1,GAD2,ALDH1L1,SRCAP,ADAM28,RND1,GPR22,KLF12,TJAP1,ITGA7,NF1,PCDH9,PDZRN4,PTPRD,RAB3IL1,TTLL7,KLHDC8A,SBF1,DOCK10,FAM214B,KANSL3,KDM4B,IZUMO4,HECW1,SYT11,SYN2,ZEB1,VLDLR,SLC17A7" Drug 2105_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.78E-05 8.72E-01 2.65E-04 3.02E-03 49 173 "ABAT,ADRB2,ARNTL,ST3GAL5,CHN2,NRXN3,ABCG1,FEZ1,CNTNAP2,CTH,NOS1AP,KIAA0513,PLPPR4,EFNA3,RGS17,ATP8A1,BAIAP2,FYN,STON1,GUCY1B1,BACH2,HSF2,DIPK1A,KIF5C,MMP16,GIT1,TAGLN3,PCDH9,PDGFRA,SERPINI1,PRPH,ENOX1,RGS4,SH3GL3,ASAP3,DZIP1,TNIK,ARHGAP26,IQSEC2,RGL1,SYT1,SYNE1,HEY1,TNS1,SSBP2,RPRM,UBE2H,DNAJC12,SLC17A7" Drug CID000009254 isoxazole Stitch 1.79E-05 8.76E-01 2.67E-04 3.03E-03 22 56 "CA4,ABCG2,MYEF2,ABCC5,PRMT5,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK5,GRM2,GRM3,HSP90AA1,ABCB1,MAPK10,SLC6A1,SLC6A11,SYN2,TAC1,SYNE1,ARHGAP9" Drug 5101_UP Prednisolone [50-24-8]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-05 8.99E-01 2.73E-04 3.11E-03 53 192 "ACTN2,AGT,APAF1,ATP6V0A1,HAP1,KYAT1,CRLF1,CACNA2D2,NRXN3,NRXN2,CRY2,ARHGEF10,MICAL2,PLCH2,SRGAP3,DMPK,ATN1,GRK4,GRIK4,ADAMTS8,GRM7,GRM8,IRAK3,KLF12,HPSE2,IL6R,KCND3,KCNMA1,LAMA2,ADAM22,MYH3,NDUFA5,NF1,SEPT4,PPARA,RGS10,MYH14,NEK11,ZNF821,DOCK10,KANSL3,SLC9A5,KDM4B,TNIK,VAMP1,COBL,KAZN,TMEM121,TIMP4,SEZ6L,LAT2,ZIC3,NAV2" Drug 4018_DN Niclosamide [50-65-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.83E-05 8.99E-01 2.73E-04 3.11E-03 53 192 "ARID1A,ALAD,KCNAB2,ARRB2,ST3GAL5,CA12,CAMK2G,KYAT1,LHX2,RAB26,CRMP1,ARHGEF10,PDE4DIP,SLITRK5,KLHL3,SMG7,EDNRA,RBM12,IRAK4,MTSS1L,EZH1,TUBB4A,ZNF589,B4GALNT1,SYT17,GBX2,HAS2,BACH2,MEF2C,MN1,MX1,NDP,POLG,MAPK7,SNRK,PTHLH,RAB3IL1,ZCWPW1,MYH14,ZFP30,SLC1A7,ARHGEF40,SLC9A5,SMARCA4,LHPP,JMJD6,DNMBP,DNAH7,TGFBR3,TNS1,UGT8,NDRG4,MPPE1" Drug 4244_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-05 8.99E-01 2.73E-04 3.11E-03 53 192 "NME5,CDC42BPA,PKP4,APAF1,PPP4R4,SLC2A11,N4BP2L1,ADGRB3,ST3GAL5,HAP1,CHRNB2,SULT4A1,AKAP12,HAPLN1,PDE4DIP,RIMS2,DAPK3,EPHB1,STX2,ETV1,DCTN2,PCDH17,RND1,BRINP3,ITIH2,KCND3,LAMA2,MAN2A2,MARK1,TM6SF1,MDM4,MT1M,NEFM,NOS1,NPR2,PDE2A,PDE3B,MAPK3,MAPK10,RAD52,GAL3ST4,MYH14,DZIP1,ZNF334,TNIK,ARC,DOCK9,OBSL1,ZFPM2,GPR161,HEY1,PARP6,PLSCR4" Drug 5667_UP Metyrapone [54-36-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.83E-05 8.99E-01 2.73E-04 3.11E-03 53 192 "ACTN2,NDRG2,ADORA2A,AMPD3,PRX,MARK4,CACNA1I,CA4,DLGAP1,RAB33A,COL9A3,MYRIP,CSF1,HDAC9,DSCAM,ING4,MRNIP,OLIG2,RCAN2,CORO2B,FHL1,FOXG1,DPYSL4,SORBS1,FAM49B,NSG1,OGA,TMEM8B,SEPT9,NEU3,SESN1,ADAM28,PCLO,GRIN1,SYNPO,IFI16,IGF1,ADAM22,NF1,NTRK3,PLCD1,PKN2,EMID1,RASA3,PKNOX2,MAPKBP1,SNCA,STX1A,R3HDM1,EMSY,SEMA3B,SLC17A7,PAK5" Drug 1221_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.83E-05 8.99E-01 2.73E-04 3.11E-03 53 192 "AMT,ATP2B2,CADM3,BACH1,C5,IL33,CFAP410,RAB26,ARMC8,CPS1,AKAP12,VCAN,GPRASP1,DSCAM,EDIL3,CNNM1,ING4,MRNIP,ETV1,EZH1,TESK2,FGF13,SRCAP,MSL3,STON1,DIDO1,SHISAL1,JAK2,VWA5A,TM6SF1,ZNF862,CNOT4,NTRK2,CLDN11,P2RX7,PDGFRA,SPATA6,PRKAR1B,PTAFR,PTHLH,TMEM231,RAB3IL1,CEP97,ZMAT4,STUM,SUPT20H,ST6GAL1,BTBD7,ZNF667,ZC3H13,MAPK8IP3,PRDM2,HPS4" Drug CID000000274 "adenosine 3',5'-cyclic phosphate" Stitch 1.85E-05 9.06E-01 2.75E-04 3.13E-03 189 907 "KCNH8,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,SYT13,AMPD2,AMPD3,PDE8B,ALDH7A1,HCN2,CDK5R1,CA4,CA8,CA12,CACNA2D1,CALM1,CAMK2B,CAMK2D,CAMK2G,SYT6,CCK,CCKBR,KRIT1,RGN,LRBA,CHGA,CHRM1,CLCN3,CLCN4,CLU,MYL6B,CNGA3,CNR1,COL9A2,COL11A2,AKAP5,CPS1,CREM,CREB5,NCOR1,CSNK1E,CSNK1G3,SDC3,PLCXD3,DCC,DMD,SHANK1,DRD1,EDN1,EDN3,EDNRA,EDNRB,KLHL5,CALCRL,TUBB3,FCGR1A,FCGR3A,FCGRT,PPP1R1B,FGF1,ACTL6B,FGFR3,CAP2,SYT3,CAMKK2,GALC,GAP43,SYT17,ATP8A2,GCK,MSTN,PPARGC1A,CRCP,GLUL,GNAL,GNAS,ATF7,LILRA2,GPR12,RAPGEF4,PLCD4,GRIK1,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,GUCY1A2,GUCY1B1,HRH3,TNFAIP8L3,CPT1C,IDH3A,IDH3B,MYLK2,IGF1,KCNMA1,KCNQ2,KCNQ3,MBP,SYT9,MYH6,MYL3,NCAM1,NF1,NODAL,NPY,NPPA,NPR2,HCN1,OPRL1,P2RY1,PDCD2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PENK,PFKFB2,PFKFB3,PFKFB4,PFKP,PHKG1,CAMKV,PKM,PLCB2,PLCD1,FTO,PPARA,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTHLH,PTH1R,PYGM,RAP1GDS1,RIT2,MAPK12,FNDC3A,PPP4R3A,MYCBP2,SST,SSTR2,SYT11,PLCB1,SYN1,SYN2,SYT1,SYT4,SYT5,AZIN2,LEFTY2,ACTR6,METTL3,TRH,CA14,TTPA,VIPR2,P2RY12,SCG2,CAMK1G" Drug CID000003857 2-amino-3-phosphonopropionic acid Stitch 1.87E-05 9.14E-01 2.77E-04 3.16E-03 27 76 "APAF1,APP,CHRM1,VCAN,GAD1,GAD2,KCNMB4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,MYH7,PRKCB,PRKCG" Drug CID005326793 Pe v Stitch 1.87E-05 9.19E-01 2.77E-04 3.16E-03 47 164 "APAF1,APOC1,BID,PRC1,HP1BP3,DYNC1I1,ATN1,KMT5B,EN2,ENO2,EZH1,FCGRT,FKTN,PPP1R1B,CELF1,AHDC1,GHR,PPARGC1A,TCERG1,CBX1,PRLHR,KAT7,PACSIN2,IGF1,NF1,NPY,OGG1,OPA1,PAH,PACSIN1,PPP2R2B,PRKCG,MAPK9,MAPK10,PTN,QDPR,ATXN7,FOXRED1,SLC1A3,SIRT2,SST,SIRT1,TTPA,MAP3K12,HPS4,FXR1,JPH3" Drug 5113_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "BRAP,MTUS1,APBB2,MARK4,ALDH7A1,CDK5R1,ARHGEF7,FUBP1,CACNA1A,SCARB1,CREM,CREB5,PDE4DIP,EDRF1,EDIL3,EDNRA,CNNM1,MBNL2,VPS26C,KIAA1109,FGF13,PNMA2,ERAP1,TMEM8B,PRRC2B,NUDT21,GRM1,RASSF8,SCIN,KCNN1,LIFR,MEF2C,NF1,PAK3,STRN3,KLK6,ZSCAN32,SEC61A2,ZNF671,ASAP3,WDR37,SLC14A1,BTBD7,SMARCD3,ZNF415,EMC1,ZBTB43,EXOC7,TK2,BEX4,TRPC1,CADM1,ZNF74,AAAS" Drug 3277_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AP2A2,APC,GAS7,FAM131A,ARRB1,ST3GAL5,QKI,SLC4A8,LRIG1,EDRF1,KIAA0513,FBXL5,DMPK,EFNA3,EGFR,SORBS3,EIF5,HSD17B14,EZH1,FER,OGA,TXNL4A,GLS,GPR37,SPACA9,NR3C1,MAP4,GIT1,NF1,NPTX1,NUCB1,PDE3B,PMS2,PTCH1,RGS12,EMID1,SBF1,SMARCD3,WDTC1,KDM4C,CLASP2,MAPK8IP3,PLCB1,ATP11A,ARHGEF12,TNS2,SLC44A1,VGF,REEP1,WNK1,EMSY,HPS4,MPPE1,SSPN" Drug 7003_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ASPHD1,NDRG3,ADRA1D,ARRB2,NCOA1,MAGI1,CACNA2D2,SLIT2,EPS15L1,EDRF1,CNNM1,EIF5,ENO2,LRRC23,DPYSL4,DOT1L,GFER,MALT1,GLYR1,GPM6A,SLC2A6,KCNH2,KIF5C,MAN2A2,MBD1,GIT1,NEUROD1,NPTX1,EPN1,RETREG2,MAPK7,PTN,FAM120C,RAD52,NEK11,FOXRED2,SBF1,ZKSCAN3,MAPKBP1,UNC5B,SPTAN1,MAPK8IP3,AJAP1,TACC1,EXOC7,ZNF34,TPM1,RUNDC3B,ZNF45,ZNF74,SLC30A3,GDPD5,SEMA3B,ST7" Drug 3573_UP Azaperone [1649-18-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "FZD9,ADORA2A,SYT13,FAM131A,ADAM23,CA4,CLDN10,USP2,ENTPD2,CHRNB2,LHX2,CPS1,CHD5,SDC3,ARHGEF4,RIMS3,PHYHIP,SRGAP3,EFNA3,PLXNC1,ELAVL3,DMTN,FOXF2,GABRA2,ALDH1L1,ADAM28,GFER,TJAP1,KCND3,KCNQ3,VWA5A,MAN2A2,ADAM22,NEUROD1,NTRK2,GPR85,SNRK,GAL3ST4,RPS6KA2,SCN8A,PREX2,SLC11A1,SNCA,IQSEC2,TBCEL,AHCYL2,TK2,AMACR,VGF,ZNF45,ZNF154,NT5M,GDPD5,KCNAB1" Drug 3740_DN Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "C1QTNF1,ADGRF5,C1QTNF3,ALK,ADGRB2,BCL7A,LARGE1,ASIC3,CHRNB2,LHX2,KIAA1549L,FAM189A2,PICK1,IFFO1,CSF1,PDE4DIP,ARHGEF4,CTNND2,CTIF,DMPK,CDON,FGF1,FGFR1,SEMA4D,MSL3,TDRKH,KCNMA1,MAP2,MOBP,CNOT4,PCBP3,PDE3B,PDPK1,MAPK7,PTCH1,RAB3IL1,ACSS3,SUSD4,ZCWPW1,RGS10,FOXRED2,SELL,SLC14A1,DDN,DOCK9,TEX15,DNAH7,TMEM121,GPR161,TNS1,CADM1,VIPR2,TFIP11,GAN" Drug 2511_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AP2A2,AGT,C1QTNF1,BCAR3,ALK,BIN1,PRX,ALDH4A1,ATP1A2,ATP1A3,RGS11,KALRN,CAMK2A,CAMK2B,BRSK2,CLCN4,CTNND1,RIMS3,AK5,DLG3,CNNM1,EPHB1,OLFM1,AFF2,B3GAT1,GAD2,ADAMTS8,GUCY1A2,RASSF8,ATXN2L,KCNC1,KCNJ5,KCNN1,MAOB,MMP16,TAGLN3,MYBPC1,MYO6,NOVA2,RIPOR1,TTLL7,ASAP3,CNKSR2,SLCO1A2,SOX2,IQSEC2,ACSBG1,TCF7L2,PCDHGA1,TLL2,TRO,UGT8,LMF1,SLC17A7" Drug 4622_UP N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AGT,APC,CDK10,NRP2,KSR1,CHN2,TPP1,CLTB,AKAP7,HAPLN1,NCOR2,ARHGEF10,PDE4DIP,C2CD2L,SGK2,SEMA3D,SIDT2,EIF4G2,ELN,EPHB1,EFS,ATP8A1,FGFR1,AGAP2,AFF2,GABRA5,GPR75,GPM6B,GRM1,GUCY1A2,ICA1,LSS,SMAD9,AFDN,GIT1,NF1,PFKFB2,PIK3R1,STRN3,TMEM231,MARCH1,RFX2,RGS12,TRAPPC13,FUZ,SLC2A5,CXXC4,PCDHGA1,TLR4,TMOD1,TUBB1,KCNK12,NUP214,GAN" Drug 3558_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "PPFIA4,EPB41L5,MARK4,ATM,CCDC181,ATP6V0A1,SCAPER,BAIAP3,CFAP410,CACNA1D,CAMK2B,USP2,CHRNA4,CLCN4,QKI,ARHGEF6,WHRN,MYRIP,SNCAIP,VCAN,CNTNAP2,RASSF2,EFNA3,EFNB3,STX2,OLFM1,HPCAL4,CSPG5,GAB1,TMEM8B,SRCAP,GPM6A,HLF,SMAD1,MAN2A2,MYCN,CNOT4,NPPA,NECAB2,C19orf57,PTHLH,FAM120C,RASGRF1,RGR,ZFP2,SLCO1A2,SNCA,KIF13A,ZC4H2,ICAM5,TPM2,AMACR,PDIA2,ZFP37" Drug 6840_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AP2A2,C1QTNF1,BEGAIN,AMH,AQP4,ALDH7A1,BAIAP3,CACNA1A,ARHGEF1,CLGN,ADGRG1,CHN2,TAOK2,FAM149A,CRMP1,NCOR2,CSF1,MICAL2,KIAA0319,MAGI2,ST8SIA3,ELAVL3,LRRC23,ERCC2,CEND1,BAIAP2,HPCAL4,GPR153,SIGLEC8,SRCAP,RND1,GNG3,GRM2,HNMT,KCNJ4,KCNMA1,KCNN2,KCNQ3,PDE1C,PDE1B,PLCD1,CDIP1,PACSIN1,MYH14,TCP11L1,SCN2B,RPH3A,FAM214B,ARHGAP26,TRIM2,ZKSCAN5,FAM155A,VIPR2,NUP214" Drug 5809_UP Natamycin [7681-93-8]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "APOC1,PPP4R4,SLC4A4,ALDH7A1,CFLAR,KSR1,BMP7,CCNT1,LARGE1,CRLF1,TAOK2,SH2B1,PLCH2,GIT2,CDON,AASS,IRAK4,MRNIP,RASGRP2,FCGRT,FGF12,C1orf61,SEMA4D,SEPT9,GNAS,IFI16,PACRG,MAN2A2,MAPT,KITLG,MPP2,BCO1,NEUROD1,LRP12,PPP1R1A,PPP5C,PTPRE,ZCWPW1,BEND5,MYH14,GSTCD,RTN1,ABLIM3,PKNOX2,SHANK2,COA1,SMARCA4,TMCC1,CEP68,SYT11,DOCK9,SLC44A1,SPHK2,TFIP11" Drug 7478_DN Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "MRTFA,APBB2,CDK13,ASPH,CFLAR,KYAT1,SMARCAL1,NECTIN3,PDE4DIP,EDRF1,GIT2,DBN1,RABGAP1L,MED12,EDNRA,TESK2,INPP5K,KCNMB4,GRB10,GRIK5,CACFD1,NR3C1,BTN2A1,JAK2,KIF5C,MPP2,OGG1,PDE3B,CCSER2,SLC25A23,STRN3,LRP12,TMEM104,ELOVL2,PEX5,RAB3A,FAM184A,GTDC1,PEX26,SMTN,LIMS2,SLC6A8,BTBD7,IFT122,HEY2,RBFOX2,NPL,METTL3,VGF,NDRG4,ST7,SMIM8,SSPN,GAN" Drug 7292_UP Epirizole [18694-40-1]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "DPF1,ADCY6,MTUS1,CDC14B,BCL7A,CFLAR,SCAPER,CBS,CBFA2T2,CDC42,FOXN3,ZFYVE9,CLCN4,STOML1,DNAJB5,PDE4DIP,CNTNAP2,CYBB,DAPK3,EFNA3,EGFR,IRAK4,ING4,RGS17,SPEG,FOXG1,IQCG,EFCAB2,SORBS1,GNG3,GPR17,CACFD1,ATXN2L,KHK,MIA2,ZNF862,LRRN3,MAPK7,RAD52,RPS6KA2,SCG5,ZFP30,SH3BP2,LIMS2,LIMCH1,ZHX3,TROVE2,THSD1,KAZN,DNAH7,TIAM1,TK2,TNS1,TPM1" Drug 7309_DN Hydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "C1QTNF1,APBB2,APOC1,PPFIA3,APP,ARRB2,EIF4G3,CFLAR,CLU,STOML1,NIPBL,PARD6A,DLG3,FEM1B,EFNA3,COQ7,F3,FGFR1,ATP2C1,ERAP1,SEPT9,COPS8,GPM6B,NUDT21,CNTRL,IFI16,SHISAL1,MBD1,MITF,NF1,NFIX,PPP5C,BCAS3,RAB3IL1,LGR4,CSRNP3,ITSN1,ASAP3,FAM214B,TNIK,ZBTB43,CAMTA2,PDLIM2,ARHGEF12,KCTD2,R3HDM1,TSN,MICAL1,NDRG4,MAP3K12,EVI5,HPS4,NAV3,URM1" Drug 6139_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "GRAMD1B,APAF1,APC,MARK4,NCOA1,SLC4A4,SGCE,ARHGAP33,RAB33A,TPP1,NMT2,SH2B1,CRY2,PPP1R16B,ZFYVE16,CTIF,RABGAP1L,MBNL2,ANKMY1,ST3GAL6,TESK2,FGFR1,PCYOX1,FAM49B,ALDH1L1,ADAM28,GLS,IL6ST,MAP4,NF1,NINJ2,OMG,CCSER2,RETREG1,PLCB2,SNRK,RAD52,RPS6KA2,CLIP1,ZNF821,AMBRA1,NUBPL,FAM214B,ZCCHC24,KIF1B,PSD3,ZNF34,RBFOX2,TRPS1,UBTF,LMF1,ZFP37,EMSY,MARCH8" Drug 4610_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,GAS7,B3GALT2,RGS11,SLC16A4,RGS6,ARHGEF10,MICAL2,CHD5,GREB1,MAGI2,RABGAP1L,HS3ST2,DTNA,ABCC9,EDN3,EFS,FAM198B,CORO2B,ZMYND10,C1orf61,AGAP2,GAB1,MYOZ2,GNAL,GNAO1,PRUNE2,GPM6B,ADAMTS8,HNMT,IL6ST,MBNL1,MYCN,MYO7A,NEFM,NF1,PIK3R1,STRN3,POU3F2,PRKAR1B,RASGRF1,GAL3ST4,TCP11L1,ANKRD6,SLC1A6,SLC8A1,DDN,SYT5,KLHL4,PCDHGB6,OBSL1,PCDHA6,DNAH7,VGF" Drug 7458_UP Cortisone [53-06-5]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "RALGAPA1,ALCAM,MRTFA,AMPH,ALDH4A1,SCAPER,CACNA1I,CACNA1D,CCKBR,FOXN3,FADS2,LY86,CREM,ARHGEF10,RUSC2,DUSP9,HIPK3,REEP2,ZNF589,CAMSAP1,TRAF3IP2,SRCAP,GLYR1,RAB30,PRUNE2,SPACA9,ADAM11,MPP2,NF1,NPR2,PCDHGC3,PLCD1,PRKAR1B,MAPK8,MYH14,GSTCD,TCP11L1,RPS6KA2,PAQR6,SBF1,IL17RB,ZNF821,CCDC88A,SLC11A1,WDTC1,ZHX3,HECW1,UNC5B,PHLDB1,WSCD1,TIAM1,KCTD2,KCNK12,TFIP11" Drug 4640_DN Domperidone maleate; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "KCNAB2,ASTN1,CADM3,CACNA1I,BAIAP3,BTRC,CA12,CBFA2T2,SCARB1,CDC42,ABCG2,CABP1,SLC4A8,CNTNAP2,DZIP3,KIAA0513,RABGAP1L,DTNB,FCF1,NRN1,KIAA1109,FGF1,FGFR3,SIGLEC8,GFER,HTATSF1,GPM6B,GPR17,CNTRL,SOX21,KCNF1,MOBP,MYH7,NDP,NNAT,PDE4D,GON4L,CNTLN,PTHLH,RGR,RGS10,FOXRED2,SUPT20H,FRMPD1,TSNAXIP1,SPTAN1,CEP68,ASTN2,RIMBP2,REEP1,DNALI1,EVI5,KCNAB1,EPM2A" Drug 5118_DN Deptropine citrate [2169-75-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADCY6,CDC7,AP2A2,BIN1,MADD,SCAPER,KRIT1,SCARB1,SOCS6,KIAA1549L,CNTNAP2,SLITRK5,ARHGEF4,DCAF4,MED24,PLEKHO1,F8,ZNF589,BAIAP2,CAMSAP1,ANKFY1,DENND2A,INPP5K,COPS8,GPER1,PCLO,HAS2,HNMT,SHISAL1,IL11RA,INPP5B,MPP2,GIT1,NUMA1,SETD4,PEX5,SEC61A2,SUPT20H,WDR37,ZNF365,SMARCD3,TNIK,ZBTB43,CEP68,TACC1,DNMBP,IQCE,TCF4,KIAA0930,PARD3,UBTF,UGT8,WNT7A,TRIM9" Drug 3825_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "PLA2G6,BEGAIN,APOC1,BCAS1,CADM3,ADAM23,NRP2,BMP7,SCARB1,ARHGAP33,NMT2,HOMER3,CREB5,HAPLN1,CNTNAP2,SLITRK5,SRGAP3,DTNA,EDNRB,RGS17,NCALD,ZNF549,DLC1,KIAA1109,PRELID3A,OGA,SYT17,GCNT2,GPR75,POLL,GNG4,ICA1,KCNB1,TAGLN3,LYRM9,NEUROD1,RETREG1,SPATA6,PKN2,PLPPR1,PTN,PTPRB,ACSS3,RAD52,RGS10,TMEM206,SH3BP2,NTNG1,PREX2,SLC6A11,ARHGAP26,DDN,AMACR,LAT2" Drug 5759_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADCY6,ADD2,APBB2,EPB41L5,AQP4,PRX,ARRB1,CCDC181,BMP7,ST3GAL5,MTMR3,CACNA1I,BTRC,CACNB2,CDH8,CACNA2D2,NRXN3,CNTFR,WHRN,CREM,NCAN,PDE4DIP,BRINP1,DNAJC6,ABCC9,RGS17,LRRC23,ST3GAL6,FGFR1,HPCAL4,SORBS1,HBS1L,PCDH17,RND1,ATF7,LMO1,ADAM22,MT1M,TAGLN3,MYO7A,NDUFA5,NPPA,PDE4D,ZSCAN32,ACSS3,TCP11L1,SEMA6D,SH3BP2,SLC15A2,HECW1,INKA2,PLCB1,PCDHGA10,PIK3R5" Drug 2974_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "MTUS1,MRTFA,FAM131A,KIF1A,MPDZ,CFAP410,NEURL1,CDH10,CHRNA4,CLCN4,CNTN1,SLC4A7,DZIP3,DBT,ST3GAL6,PDLIM5,PTGDR2,KHK,KIT,VWA5A,MGAT3,AFDN,GIT1,NCAM1,PDE4D,NLE1,PLCD1,PTPA,CEP41,PTAFR,RGS4,ARHGEF10L,MYH14,TMEM206,RYR1,RASA3,CPEB3,PREX2,SLC11A1,SNCA,TMCC1,IZUMO4,SPTAN1,SS18,CAMSAP2,PDLIM2,TCF4,PCDHGA10,SLC44A1,RBFOX2,TRPC1,VIPR2,KCNAB1,NLRP3" Drug 6791_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AP2A2,APC,PLA2G4C,ASPH,BTRC,CA12,SLIT2,QKI,DCAF8,GIT2,SEC16A,DTNA,CELSR3,PLEKHO1,COQ7,FGFR1,BAIAP2,GLS,BTN2A1,RNFT2,MAP4K5,MUM1,DHX35,IGSF1,INPP5B,CNOT4,PDE3B,RETREG1,PTCH1,PEX5,RAD51D,RNASEL,GSTCD,ROBO1,PAQR6,ZNF821,ITSN1,SMTN,SLC20A2,PDZRN3,SOX3,ZHX3,EMC1,THSD1,ARC,DNMBP,TCF7L2,TRIM2,KCTD2,ZMYND8,SF1,NDRG4,EPM2A,PHTF2" Drug 5638_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ALK,SLC4A4,KSR1,CCK,AKAP5,RASSF2,SPOCK2,HEPH,NTM,DMPK,ATN1,ING4,ERCC2,FGF13,FGFR1,FLT1,GAB1,GABRG2,ADAM28,SPACA9,ADAMTS13,GRIK5,KCNN1,KIT,MDFI,CDK18,PDE4D,PFKFB2,LRRN3,RELN,PTAFR,PTHLH,WLS,SLA,FAM214B,KANSL3,SLCO1A2,OGDHL,KIF13A,BEX1,ATP10B,INKA2,SYN2,TAC3,TACR1,ADGRL3,TRIM2,HIF3A,DNAH7,HEY1,UBE3A,UCHL1,WIPF1,KCNAB1" Drug 2135_UP Conessine [546-06-5]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,ADD2,ADORA1,BIN1,SEMA4G,ADGRB1,CACNG1,CAMK2B,INA,CBFA2T2,NMT2,CREM,FAM169A,RIMS2,NOS1AP,EEF1A2,SGK2,VPS13B,FGF1,BAIAP2,FOXG1,GFER,PCDH17,LILRA2,GRIA4,CACFD1,ADAMTS8,KLF12,MMP16,NPY,NUMA1,CEP41,KLK6,CNNM2,PTPRB,SBF1,ZNF821,MRAS,SLC11A1,SLCO1A2,TMCC1,ZNF423,ZC3H13,SEPT8,CEP68,SYNE2,TRIM2,ATP13A2,GPR161,TGFBR3,ZKSCAN5,FLRT1,VSNL1,CAMK1G" Drug 5480_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADORA2A,AGT,NME5,PLA2G6,CNTNAP1,GAS7,ASTN1,ATP2A2,GYG2,LDLRAD4,CHN2,CNTNAP2,SPOCK2,DOCK2,ELAVL3,DMTN,LRRC23,OLFM1,ANKFY1,GABRB1,GLS,GNAO1,CNTRL,GRIK5,NR3C1,HSF2,KCNC1,MMP16,ADAM22,NPPA,CDK14,PGAM2,RETREG1,PLEC,PACSIN1,RGS12,RPS6KA2,ZNF821,ABLIM3,ELMO2,HECW1,ZC3H13,VAMP1,SEMA4A,RPGRIP1L,TEX15,TGFBR3,AMACR,TRPC1,VIPR2,MICAL1,ZNF45,PARP11,FAM13C" Drug 6715_UP Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "KIDINS220,ADGRF5,PKP4,N4BP2L1,BMP7,KALRN,CAMK2B,CACNA2D2,NRXN3,NMT2,IFFO1,SUSD5,ATRNL1,RIMS2,MFAP3L,AK5,ST8SIA3,SIDT2,OLIG2,RASGRP2,TRAF3IP2,SIGLEC8,GPM6B,STON1,GRIK2,GRIK5,SOX21,PTGDR2,KLF12,HLF,HTR5A,MAOB,MOBP,MYH3,MYH7,SLCO1C1,CNOT4,P2RY1,SNTG1,PMP2,MAPK8,PROX1,PTCH1,MARCH1,TCP11L1,CPEB3,NTNG1,PKNOX2,INKA2,SYT5,RIMBP2,TNS1,VLDLR,NLRP3" Drug 2735_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ALK,AMPH,ANK3,PPFIA4,ASPH,CCDC181,CADM3,ADGRB1,GYG2,CFAP410,TMEM257,ARHGAP33,CHRNA4,DNAJB5,PICK1,CRYBB1,NCOR2,CTNND1,RIMS2,EXOG,CDON,AASS,EPB41L1,ERBB2,DLC1,FHL1,ZNF44,B4GALNT1,SIGLEC8,SEPT9,RUNDC3A,PRUNE2,GRK4,GRM8,KCND3,KCNMA1,AFDN,MYO6,NEUROD1,RASGRF1,KHDRBS2,FRMPD1,CNKSR2,ACSBG1,ROBO3,CHST8,TIAM1,TRIO,AMACR,BEST1,SCG2,FAM13C,TIGD6,JPH3" Drug 2117_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ABR,ADCY6,NME5,BIN1,OGT,EP400,APBB1,APP,ATP2A2,KIF1A,MTMR2,HIP1R,KRIT1,SCARB1,RAB28,TPP1,ARMC8,PDE4DIP,CNTNAP2,ARHGAP24,CDON,ABCC9,EDIL3,EFNA3,ANKMY1,FOXG1,SORBS1,GAA,WASF3,GLRB,GPER1,HNMT,IL6ST,IL11RA,INPP5B,NFYA,NUMA1,PRKAR1B,MAPK7,RAD52,SH3TC2,GAL3ST4,RGS4,SCN8A,ASAP3,SLC20A2,KDM4B,FNBP1,IQSEC2,ZBTB43,COBL,TRIM2,ZKSCAN5,PRDM2" Drug 3685_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ABHD6,MRTFA,APBB2,CDK13,ASPH,ADAM15,SCAPER,CBFA2T2,LARGE1,FOXN3,SOCS6,CHN2,RAB28,IQCK,CHD1L,NCOR2,CSF1,VCAN,PDE4DIP,DZIP3,CTH,PLPPR4,PDLIM5,HBS1L,GPM6B,CACFD1,GUCY1B1,ELOVL5,HNMT,KCNJ5,MBNL1,NFYA,PLEC,PRPH,TMEM231,DZIP1,ELMO2,SNCA,SS18,NXT2,SYT1,COBL,ASTN2,KIAA1107,AHCYL2,GPR161,BEX4,TPM2,TRIO,TRPM2,ZMYND8,VAV2,NSD2,WNK1" Drug 4718_DN Cefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "SLC12A5,MRTFA,APC,MARK4,SYNJ2,LHX2,PLAA,TPP1,COL4A5,ABI3BP,BAG4,EDRF1,CTIF,BRINP1,RUSC2,KBTBD11,AASS,SORBS3,HSD17B14,CDKL3,ST3GAL6,FHL1,GFER,GNG4,GRM8,IL6R,LMO2,MPP2,ADAM22,NDUFA5,NEUROD1,NUMA1,RETREG1,PPARA,SAMD9,PTN,RAB3IL1,RPS6KA2,ABLIM3,EPN2,SNCA,SOX2,ZCCHC24,ZSWIM8,ARHGAP26,MAPK8IP3,VPS13A,SMG6,TRIM2,FAM155A,VGF,VIPR2,KCNK12,XRCC4" Drug 7502_DN CP-944629 [668990-94-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "CDC42BPA,ARNTL,CDK13,ASPH,ADAM15,MYRF,IL33,CNOT8,CLU,NIPBL,CHD1L,CSF1,CTH,USP6NL,FEM1B,FCF1,FAM13A,ABI2,ELAVL2,COQ7,ETV1,ANKMY1,EFEMP1,FER,FHL1,WASF3,C1QL1,RND1,GLYR1,GLUL,POLL,KIF3A,MBNL1,MYO6,NDP,RETREG1,PTPN13,CCDC40,RFX5,IL17RB,MRAS,ITSN1,PEX26,SLC14A1,BTBD7,BEX1,ARHGAP26,ZBTB43,SRPK2,ATP10B,AHCYL2,NSD2,SH3GLB2,MPPE1" Drug 3112_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,ARID1A,KIDINS220,AP2A2,CNTNAP1,APBB2,PPP4R4,ARHGDIG,PLA2G4C,ALDH4A1,BCL2L2,LARGE1,MAGI1,CREM,SH2B1,CRY2,PDE4DIP,RIMS3,BRINP1,ATN1,DYRK1A,SIDT2,CELSR3,VPS13B,LRRC23,FOXG1,C1QL1,PRUNE2,GPM6A,GRM7,MYO6,ABCB1,SERPINI1,CCSER2,POU6F1,MASP1,PEX5,TCP11L1,SYNDIG1,RYR1,SH3BGR,NTNG1,ANKRD6,SLC1A3,SLC14A1,PEG10,CDK19,LMO3,TRPC1,TRPS1,TMPRSS5,UBE3A,VAV2,PLSCR4" Drug 5768_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "RALGAPA1,TTYH1,ASPHD1,BEGAIN,APC,KIF1A,BMP7,BTRC,CACNB2,HIP1R,NEURL1,CHRNA4,LY86,HOMER3,COL9A2,MFAP3L,EDNRB,PLXNC1,PIPOX,CEND1,FOXF2,ERGIC3,SRCAP,GLS,POLL,GPM6A,GPR17,GRIA4,ADAMTS13,CACFD1,GSTM5,ITIH2,KCNB1,KCNJ4,KIFC3,MAOB,SHC3,AFDN,CD200,NPPA,PDE4A,ABCB1,DIRAS2,PID1,RGS3,TCP11L1,FOXRED2,STUM,RASA3,SLA,TEX15,TMOD1,SEMA3B,DPF3" Drug 5246_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "FZD9,ADORA1,PRX,CADM3,KSR1,CACNA1I,CCKBR,CYBB,DGKG,CTIF,HS3ST2,CDON,ATN1,PHF20L1,PLXNC1,REEP2,KIAA1109,FOXG1,KHDRBS3,ALDH1L1,RUNDC3A,STMN2,GRIK5,HRH3,HLF,AFDN,PDE1C,PDE1B,CDK14,PLP1,MAPK7,PLPPR1,PTX3,RAD52,ZMAT4,KLHL11,SALL1,SH3BP2,SLC2A5,KANSL3,SNCA,KIF13A,ZNF415,DOK5,COLGALT2,ATP11A,SZT2,TMEM151B,TEK,DNAH7,LILRA4,TRH,SLC17A7,FAM13C" Drug 1438_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "NDRG2,C1QTNF1,ALDH4A1,CFLAR,MTMR3,OSBPL3,CTNND1,RUBCN,HP1BP3,FEM1B,ABI2,ING4,BSCL2,EPB41L2,FCGRT,FGFR1,PRKAG2,ATP2C1,GAA,SRCAP,RUNDC3A,GRIK5,BTN2A1,MUM1,AGBL5,KIF2A,VWA5A,AFF1,NACA,NELL2,NF1,RETREG1,PLCD1,ZNF426,GON4L,PTPRN2,GAL3ST4,MYH14,FAM102A,KBTBD4,ELMO2,TBL1X,EHBP1,TK2,TNS1,CHST5,TSN,CA14,VIPR2,XRCC4,PRDM2,MPPE1,ACTR3B,ZNF248" Drug 4014_UP Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AMPH,APC,SLC4A4,ADAM23,BTRC,RUNX1T1,CBS,CBFA2T2,CDC42,ARHGAP33,CLCN4,AKAP5,ENTPD4,CNTNAP2,ERC2,MAGI2,SMG7,DTNB,EDNRA,TENM1,EPHA5,DLC1,NEU3,GLYR1,GRM2,GRM7,IL6ST,JAK2,MMP16,NEUROD1,NF1,SLCO1C1,NNAT,CNOT4,NPTX1,PDE2A,TNPO2,MAPK10,PTPRN2,RAD51D,RAD52,C1orf54,GAL3ST4,RNASEL,MRAS,DOCK10,SOX15,ARHGAP26,COBL,AP4E1,WNK1,NLRP3,AAAS,DPF3" Drug 3319_DN Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "BCAS1,PPFIA3,CDK10,ASPH,STX16,CFLAR,SYNJ2,MTMR2,GYG2,HAP1,CLGN,QKI,SLC4A8,ENTPD4,CTNND2,DAPK3,DCTN1,PARD6A,RCAN1,OPTN,SUGP2,KIAA1109,PRELID3A,TDRKH,DHX35,IL6ST,ITPKB,PDE3B,NLE1,SLC25A23,PRKAR1B,GON4L,TMEM104,RGS12,ARHGEF10L,SLC25A36,SBF1,TRA2B,SH3BP2,FAM214B,BTBD7,ZCCHC24,EMC1,THSD1,DIP2A,TACC1,TCF7L2,ZKSCAN5,PLPPR2,WNK1,EMSY,EPM2A,UBE3B,RNF170" Drug 5633_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADD2,C1QTNF3,AMPD3,SEMA7A,APAF1,CDC14B,ALDH4A1,ALDH7A1,CCKBR,WHRN,CPS1,NCOR2,CRYM,NOS1AP,ATN1,SIDT2,EFNB3,RASGRP2,ETV1,HPCAL4,GPR153,GNAO1,GPM6B,KCNC1,KCND3,KCNH2,KCNK2,LMO1,MSI1,MX1,NOVA2,OMG,CDK14,PURG,MAPK8,CNNM2,PTPRB,MARCH1,C1orf54,KCTD17,SP4,PEG10,SSTR2,RGL1,RPGRIP1L,SLC44A1,TNFRSF1B,TPM3,UBE3A,VAV2,SPHK2,SLC30A3,DNALI1,DPF3" Drug 1501_UP Tolnaftate [2398-96-1]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AMPD3,BIN1,APBB2,ASPH,SCAPER,CDC27,CACNA2D2,SOCS6,NIPBL,COL4A5,SLC4A7,CREM,ENTPD4,LRIG1,ZFYVE16,GIT2,LYPD1,RRAGB,F3,CAMSAP1,ATP2C1,AHDC1,GLYR1,RAB30,TDRKH,GPR37,GRIK5,RNFT2,IGSF1,KCNH2,KIF5C,MBD1,MSI1,NEK1,SETD4,RETREG1,PRODH,PTCH1,SH3BP2,FBXO11,PPP4R3A,MAPK8IP3,TACC1,IQCE,TRIM2,PSD3,TMOD1,TPM1,CDK20,KCNAB1,MPPE1,MVB12B,ADAMTSL3,SSPN" Drug 6623_DN Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "MRTFA,BIN1,CDC42BPA,APC,DNAH17,ASPH,ALDH4A1,ATM,ARHGEF2,RAB28,HOMER3,IQCK,CREM,NCOR2,DZIP3,C2CD2L,TMCC2,CDON,RGS17,CDKL3,ETV1,BAIAP2,SEMA4D,FYB1,DISC1,SEPT9,SCIN,IL6ST,MAP4,AFDN,MX1,PFKFB2,PIK3R1,MBOAT7,FA2H,PPARA,PTPA,WDR25,RIPOR1,ZDHHC14,RGS10,TCP11L1,RPS6KA2,RXRA,ZNF667,KDM4B,EMC1,DDN,RPGRIP1L,TIAM1,TNS1,MICAL1,WNK1,NT5M" Drug 3031_DN Rolitetracycline [751-97-3]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADORA2A,APAF1,APBB2,APOC1,CDK10,ASPH,NCOA1,KIF1A,CDK5R1,SCAPER,LDLRAD4,HIP1R,KYAT1,CD86,B4GALT6,EPS15L1,ZFYVE9,TPP1,SH2B1,RUSC2,CDON,DTNA,MBNL2,SORBS3,EIF5,ING4,STX2,FER,INPP5K,LILRA2,SPACA9,SLC2A6,NCKAP1L,ATXN2L,NF1,PLEC,SLC25A23,PRKAB2,PTAFR,RAD52,RALGDS,SEC14L1,RASA3,FBXO11,ARFGAP1,KDM4C,DDN,TCF4,ZEB1,TNNT1,SSBP2,FLRT2,SPHK2,ZNF248" Drug 5753_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,TRMT9B,ANK1,SEMA7A,AQP4,SLC4A4,ATP6V0A1,ADGRB2,BMP7,HAP1,CD86,NEURL1,CDH8,NRXN3,ABCG2,AKAP7,MYRIP,PLCH2,PDE4DIP,CTIF,DSCAM,DTNA,ABCC9,EDN1,PLXNC1,ATP8A1,FOXG1,GABRA5,SEPT9,POLL,ATF7,HRH3,ELOVL5,ITGA7,ITPKA,KCND3,KCNN1,NTRK2,OPRL1,PDE4D,ENOX1,RGS10,STUM,DZIP1,HECW1,IQSEC2,DDN,MCF2L,ICAM5,TLR4,PIK3R5,TRIO,AMACR,SENP7" Drug 2879_UP Ethamivan [304-84-7]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AP2A2,SRPX,LTBP4,AMH,AMPD3,APAF1,APOC1,PLA2G4C,CDK13,ADAM23,CFLAR,CACNA2D1,CACNB2,CBFA2T2,SIPA1L1,SPOCK2,BRINP1,RUSC2,CDON,EDNRA,C3orf18,HSD17B14,TPK1,GABRA5,GLS,GPER1,NR3C1,ICA1,ITGAM,KCNH1,KCNJ5,KIT,LMO1,MIA2,TAGLN3,CNOT4,PFKFB2,PLTP,MINDY2,TRIM68,EMID1,SELL,SLC1A7,SLN,MAPKBP1,ARC,ATP11A,DMXL2,KIAA0930,PARD3,TNS1,KCNK12,GDPD5,KCNAB1" Drug 2468_UP Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,ADCY2,ANK3,PPFIA3,KIF1A,BAIAP3,CFAP410,CALB2,CAMK2B,ARHGEF1,ZFYVE9,STOML1,SULT4A1,AKAP7,COL9A3,ABI3BP,CRMP1,CSF1,ARHGEF10,RIMS2,SPOCK2,DLG4,EXOG,ATN1,OPTN,RASGRP2,ERCC2,FGF12,FGFR1,GLYR1,GNAO1,GRIN1,GUCY1B1,IL12A,KIT,NNAT,NPTX2,NTRK2,OMG,KCNK10,CAMKV,PLCL1,CEP97,CCDC40,RGS10,SNCA,SOX2,SYT5,SLC19A3,CRTC1,RPRM,VAV2,LMF1,KCNAB1" Drug 1514_UP Metolazone [17560-51-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AMPD3,BIN1,APC,MARK4,ATP1A3,ATP6V0A1,SYNJ2,CACNA1I,CD86,TAOK2,FADS2,SLC4A8,CRMP1,LRIG1,ATRNL1,RIMS3,EFNB3,PHF20L1,FOXG1,DPYSL4,GPR153,C1QL1,RUNDC3A,TXNL4A,GRIK2,ADAMTS13,GRIK5,DHX35,IL6ST,MATK,KCNK10,PPP5C,ZDHHC14,RFX2,KCTD17,KCNIP1,SYBU,ZNF365,FAM214B,BTBD7,SLC22A4,RBM34,KDM4C,ERC1,SAMSN1,INKA2,MAPK8IP3,TTBK2,RUNDC3B,LAT2,ZBTB14,ZIC3,GDPD5,UBE3B" Drug 6289_DN Ganciclovir [82410-32-0]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AK2,BIN1,PKP4,FAM131A,CDC14B,ATM,PUM1,TM9SF4,GIT2,DBN1,DBT,B3GAT3,HP1BP3,PARD6A,SPOCK3,FEM1B,RBM12,ELAVL2,EPB41L1,F3,CINP,TXNL4A,MSL3,HTATSF1,FERMT2,DIDO1,BTN2A1,MAP4,MYO6,PBX1,PCDH9,PDE1C,PIK3R1,PTPA,PRPH,CNNM2,ELOVL2,PEX5,SH3TC2,RPS6KA2,MAPK12,SUPT20H,TRA2B,SH3BGR,FAM102A,ABLIM3,SLC1A3,SHANK2,ZKSCAN3,KDM4B,UNC5B,CBX5,PLPPR2,NAV3" Drug 2944_UP Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ABHD6,ARID1A,KIDINS220,BCAR3,APC,SLC4A4,STX16,N4BP2L1,MTMR2,LDLRAD4,NIPBL,CTIF,DCTN1,E2F5,HIPK3,SIDT2,ABI2,RASGRP2,F5,FAM49B,SEPT9,GATM,RND1,LILRA2,PADI2,TJAP1,ITGAM,JAK2,KIF2A,LIG4,MAP4,GIT1,CCSER2,MINDY2,SNRK,ZSCAN32,PTPRN2,RAB5B,DHX30,TSNAXIP1,SPTB,STXBP1,CAMSAP2,TBCEL,TCF4,ZEB1,TLR4,PIK3R5,RBFOX2,CDK20,TRPS1,FAM155A,EPM2A,NLRP3" Drug 6830_UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "MRTFA,SEMA7A,APBA2,GAS7,CCDC181,ALDH7A1,ARHGEF2,ZFYVE9,VCAN,PDE4DIP,SLITRK5,RUSC2,SPOCK3,CDON,ELAVL3,TNK2,NCALD,PTK2B,FOXG1,ADAM28,RUNDC3A,GNG3,STON1,GRM1,GRM7,KLF12,KCNA4,KCNB1,KCNMA1,MAOB,ADAM22,PENK,PGAM2,PIK3CD,SLC25A23,PTCH1,PTPRO,RAD52,FAT4,RFX2,SEMA6D,ASAP3,SLC6A9,SNCA,SOX2,VAMP1,DMXL2,TNS2,TMOD1,FAM155A,VLDLR,XRCC4,SLC17A7,KAT6A" Drug 2526_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "NDRG2,BRAP,AP1B1,ARRB1,NUMB,ADAM15,CACNA1A,CAPN3,AKAP7,BAG4,CTNND1,KIAA0753,SGSM2,DTNA,CELSR3,SORBS3,LRRC23,RASGRP2,ST3GAL6,ARFIP1,SLC2A6,ICA1,MAP4,MIA2,ZNF862,MYT1,PDE4D,SERPINE2,RC3H2,MAPK8,PTX3,TMEM231,RXRA,TRAPPC13,SBF1,GALNT10,ITSN1,PPP4R3A,ZKSCAN3,SNCA,ZCCHC24,EMC1,UNC5B,DDN,JMJD6,ARHGEF9,TMOD1,PARD3,CDK20,PLPPR2,XRCC4,ZNF74,GDPD5,FIP1L1" Drug 6483_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ASPHD1,ADCY6,APP,PDE8B,CFAP410,CBLN1,CLGN,CHRNB2,FADS2,WHRN,RIMS2,DAPK1,MFAP3L,RCAN1,EDNRB,FCF1,ELN,EML1,LRRC23,DLC1,FOXG1,ANKFY1,DCTN2,SORBS1,FYB1,GAB1,HBS1L,GPM6B,GPR22,NR3C1,ICA1,ITIH2,KCNMA1,KIT,NFYA,OMG,PALM,EPN1,SLC25A23,PRKAR1B,RALGDS,KCTD17,CCDC25,RPS6KA2,PPP4R3A,ZCCHC24,SOX10,PLCB1,SYP,HIF3A,TLR4,XRCC4,SLC30A3,PHTF2" Drug 1481_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ASIC1,ADORA3,AP2A2,APBB2,CDK13,ALDH4A1,ST3GAL5,SCAPER,CFAP410,CA4,CDH8,SOCS6,TAOK2,RIPOR2,SNPH,RIMS3,DMPK,DNM2,MBNL2,ERCC2,CAMKK2,OGA,ADAM28,ADAMTS13,GRIK5,GRIN2C,IL12A,KCNH1,LSS,MBD1,MGAT3,MMP16,MSI1,NUMA1,CDK18,CAMKV,RETREG1,PLCD1,CEP41,PTCH1,PTHLH,CCDC40,FAM184A,SYNDIG1,PKNOX2,SLC6A8,MYH15,SOX2,SYP,IQCE,TPM3,SLC13A3,ST7,SSPN" Drug 5285_UP Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "RBM10,NDRG3,AP2A2,C1QTNF3,LTBP4,DOC2A,SYNJ2,C5,CFAP410,ARHGAP33,B4GALT6,VAX2,SLC4A8,SOCS5,PDE4DIP,RABGAP1L,DSCAM,EFNA3,SUGP2,EGFR,VPS13B,COQ7,STX2,NCALD,ANKMY1,BAIAP2,AGAP2,OGA,GABRA2,POLL,DIDO1,NF1,NFYA,OGDH,LRP12,LRRC49,NKAIN1,GTDC1,ABLIM3,ZNF430,BTBD7,LIMCH1,SPTAN1,NXT2,FCHO1,MAPK8IP3,CEP68,ATP11A,TBL1X,TCF7,TRIM2,TPD52,PLPPR2,SSPN" Drug 4433_UP 2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,SEMA7A,BRINP2,ATP2B2,KIF1A,GYG2,CBS,LDB2,CACNA2D2,NRXN3,WHRN,CRY2,RIMS2,EDRF1,SPOCK2,DSCAM,DTNA,ETV1,ANKMY1,REEP2,FGF1,OLFM1,FOXG1,GAB1,GLI2,MSL3,GPM6A,GPR19,SPACA9,ATXN2L,KCNH2,AFF1,ADAM22,SNTG1,PALM,PGAM2,DUSP26,MBOAT7,MAPK7,PTPRN2,GAL3ST4,RGS4,RNASEL,CPEB3,LIMS2,PKNOX2,ARHGEF40,SNAP25,ZSWIM8,RBM26,TPM1,TRIO,VAV2,SPHK2" Drug 5697_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "BIN1,APOC1,ARRB1,ALDH4A1,CA4,KYAT1,CLGN,ZFYVE9,BAG4,SIPA1L1,DZIP3,CTH,RIMS3,DAPK3,GIT2,LYPD1,DTNA,EFNA3,ING4,EN2,KIAA1109,MALT1,POLL,CNTRL,LIG4,MAP4,KITLG,MITF,ADAM22,NFYA,SERPINE2,ZSCAN32,CEP97,RALGDS,NEK11,FBXW7,MAP6D1,ASAP3,FUZ,EPN2,BTBD7,SLC22A4,THSD1,CEP68,ARHGEF9,SEMA4A,KIAA0930,TCF7,THRA,XRCC4,WNK1,EVI5,SCG2,ACTR3B" Drug 6669_DN Benzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "AMPD3,APAF1,APC,ADAM23,NRP2,CFLAR,CDK5R1,SCAPER,CACNA1A,NEURL1,FOXN3,CHN2,B4GALT6,ARMC8,WHRN,SPOCK3,EXOG,EDNRA,MBNL2,TENM1,KIAA1109,ZMYND11,GPR37,GRM8,VWA5A,MDFI,MMP16,MX1,LYRM9,PIK3R1,LRP12,PTPRH,ZCWPW1,NUDT11,NEK11,RPS6KA2,RXRA,ST6GAL1,DZIP1,TMCC1,TNIK,SPTAN1,CDK19,TROVE2,THSD1,CEP68,KIAA1107,TBCEL,TCF4,DNAH7,TK2,TSC1,LAT2,NAV3" Drug 2143_DN Gramine [87-52-5]; Down 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ABHD6,APBB2,CACNB2,CAMK2G,CDH10,SOCS6,RAB33A,ARHGEF10,CSNK1E,TM9SF4,DGKG,DAPK3,CTIF,SMG7,HIPK3,EFNA3,PLXNC1,ELN,RASGRP2,KAT8,SEMA4D,FLT1,AFF2,INPP5K,SRCAP,USP19,MSL3,POLL,LILRA2,IDH3A,KCNJ5,MEF2C,PLCB2,POU6F1,MAPK8,PTPRN2,RAB3IL1,CEP97,RAD52,DPF2,RXRA,ZNF821,SH3BP2,EPN2,FAM214B,DOK5,PLCB1,ATP11A,TCF7L2,TPM1,PLPPR2,VIPR2,XRCC4,EVI5" Drug 7150_UP "(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "APC,BMP7,CACNA1G,MYRF,CACNB2,CBFA2T2,ZFYVE9,RAB26,WHRN,VCAN,CNTNAP2,ARHGEF4,CTNND2,FAM131B,MFAP3L,RUSC2,SMG7,EFNA3,FAM13A,SORBS3,EN2,EZH1,ST3GAL6,OGA,ZNF44,GAD2,SYT17,SESN1,C1QL1,GRM8,INPP5B,MAPT,NF1,PALM,PDGFRA,PRKAR1B,CNNM2,BCAS3,RAB3IL1,GTDC1,CCDC25,FBXW7,RPS6KA2,SH3BP2,PPP4R3A,SLC6A9,SOX2,ERC1,DDN,ASTN2,TIMP4,TK2,PARD3,ZMYND8" Drug 3182_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADD1,LTBP4,MARK4,ASPH,ATP6V0A1,KIF1A,CDK5R1,C5,CAMK2G,CLCN3,STOML1,ARHGEF6,AKAP7,CHD1L,SDC3,ZNF337,CTIF,DBN1,EIF5,CAMSAP1,ANKFY1,DPYSL4,ZNF44,GALC,SYT17,MALT1,CNTRL,HNMT,KCNH2,LMO2,MAPT,MIA2,NF1,CNOT4,PC,RETREG1,WDR25,RPS6KA2,SBF1,ZNF821,EPN2,SCMH1,KDM4B,CLASP2,POGZ,NCDN,MAPK8IP3,VAMP1,SEMA4A,KIAA0930,TNS2,CABIN1,TPD52,VAV2" Drug 4754_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "FZD9,AMPD3,CDH2,CRLF1,CHI3L2,CHN2,EPS15L1,CNN3,AKAP7,MYRIP,CPS1,CSF1,RUSC2,C2CD2L,PLXNC1,C3orf18,EPHB1,CDKL3,REEP2,FHL1,FYB1,DKK3,GABRA2,ZNF44,GNAL,GNG3,GRK4,KCNC1,PACRG,SMAD1,MDFI,MOBP,PCSK2,CDK14,MTRF1L,PTHLH,EMID1,RPS20,RASA3,KANSL3,LIMCH1,ZNF415,RBM26,SPART,ATP11A,ZEB1,PSD3,PARD3,TPM1,CHST5,TUBB1,KCNK12,SLC30A3,DNALI1" Drug 6399_UP C75; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "KDM5D,PLA2G6,APC,CDK10,DNAH17,BRINP2,ALDH4A1,ATP6V0A1,RGS11,BAIAP3,CDK5R2,LHX2,SLC24A2,HOMER3,WHRN,ABCG1,SLITRK5,CTIF,MFAP3L,FRY,PLEKHO1,NCALD,EXTL1,HPCAL4,C1orf61,GAD2,TDRKH,FAM107A,ITGA7,KCNQ3,NF1,NTRK2,PDE4D,PDGFRA,TNPO2,CEP41,PRKAR1B,PTPRN,RAB3IL1,C1orf54,BEND5,TTLL7,SEC61A2,RNASE1,DOCK10,SLC6A11,ZSWIM8,DDN,ARC,ATP11A,TBCEL,CDK20,CA14,SPHK2" Drug 6428_DN C75; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "APC,ST3GAL5,CFAP410,CBFA2T2,RAB26,PICK1,TCEAL2,CREB5,PDE4DIP,CNTNAP2,PHF14,PPP6R2,DCAF8,RIMS3,DAPK3,LYPD1,SPOCK3,DLG3,EZH1,KAT8,ZNF589,CINP,PDLIM5,SRCAP,POLL,GNG4,GPR17,KIF3A,ARHGAP19,KIFC3,MAP4,MITF,CNOT4,SMIM7,MAPK7,PTN,PTPRH,RGS10,RPS6KA2,SH3BGR,SLC4A3,SMARCC2,ZNF415,SPTAN1,RAP1GAP2,THSD1,MAPK8IP3,ASTN2,TIAM1,RUNDC3B,ZKSCAN5,WIPF1,WNT7A,PCBP4" Drug 7358_UP Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "DOC2A,BIN1,AMT,BCAS1,DNAH17,CFLAR,CRLF1,CBARP,B4GALT6,WHRN,NCOR2,FAM169A,SNPH,MRNIP,STX2,AFF2,DPYSL4,DISC1,PRUNE2,GPR19,CNTRL,NR3C1,RNFT2,RASSF8,ATXN2L,ELOVL5,HNMT,MAPT,MITF,ADAM22,LYRM9,NPTX1,NRGN,OGG1,TMEM104,PTHLH,ZSCAN2,RAD52,RGS12,PBRM1,TCP11L1,SBF1,SYBU,LIMCH1,RBM34,SOX3,FNBP1,HECW1,ZBTB43,RBM26,NPAS3,PCDHA5,ATP13A2,CHST8" Drug 5751_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ASIC1,ADRA1D,AP2A2,ARNTL,ALDH4A1,BTRC,KYAT1,CBFA2T2,B4GALT6,LHX2,ZFYVE9,HAPLN1,CSF1,EDRF1,MFAP3L,SGSM2,TOM1,MRNIP,RRAGB,EZH1,CGREF1,GBX2,SRCAP,GNAS,GPR37,GUCY1B1,KLF12,MPP2,MT1M,NF1,NPR2,RETREG1,GRAMD1C,PTPRE,PTPRN2,RIPOR1,RAD52,ARHGEF10L,MYH14,GSTCD,RPS6KA2,PAQR6,ASAP3,SLC14A1,IFT122,SAMSN1,TNS2,GPR161,ZMYND8,UGT8,LMF1,MAP3K12,VPS35L,RNF146" Drug 6663_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ABR,ACTN1,ARID1A,KIDINS220,GAS7,CDK5R1,CBFA2T2,SYNGR3,REPS2,PDE4DIP,TBC1D5,MAMLD1,TENM1,LRRC23,EPHA5,PNMA2,RASSF8,TJAP1,SCIN,LYRM9,NF1,CNOT4,NPR2,PLXNB1,MAPK7,CNNM2,PTX3,SH3TC2,FAT4,ROM1,RPS6KA2,ZNF821,DOCK10,FUZ,AMBRA1,DZIP1,SHANK2,SLC14A1,LIMCH1,TMCC1,TROVE2,ELOVL4,FAM168A,JMJD6,TRIM2,SYNE1,SLC44A1,BHLHB9,TNS1,WIPF1,EMSY,NAV3,SMIM8,PHTF2" Drug 7388_UP PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "CDC42BPA,KCNAB2,RGS20,BTRC,CALB2,SLC16A4,CACNA2D2,FOXN3,TAOK2,WHRN,CREM,CNIH3,RUSC2,EXOG,USH1C,FAM13A,IRAK4,ING4,DMTN,BAIAP2,SIGLEC8,ZNF276,GLRB,GNG3,GPM6B,SHISAL1,DIPK1A,ITPKA,KCNH1,CLDN11,PDE4D,RETREG1,SMIM7,PPARA,PTPRN2,ARHGEF10L,EMID1,ASAP3,TSNAXIP1,IQSEC2,ARHGEF9,ASTN2,KAZN,DOCK9,AHCYL2,TK2,ZKSCAN5,WIPF1,XRCC4,SEMA3B,KCNAB1,PLSCR4,UBE3B,NUP214" Drug 6704_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADCY2,ADGRF5,PPFIA4,GAS7,ASPA,NOL4,KSR1,BTRC,CALB2,NEURL1,KCNAB3,ABCG2,CSF1,SUSD5,SPOCK2,PLPPR4,ATN1,DSCAM,DYRK1A,ELN,APC2,CEND1,NRN1,GPER1,GRIK5,GRM2,ITGA7,KCND3,VWA5A,SMAD1,NHLH1,CNOT4,NOVA2,PDE3B,PPP5C,MASP1,ZSCAN32,PTPRB,RGS12,RPS6KA2,SH3BP2,PKNOX2,SLN,RIMS1,SNCA,SOX2,LHPP,ARC,TLR4,TPM1,TRPC3,VIPR2,PARP11,GAN" Drug 3438_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADCY6,DOC2A,BIN1,APC,APOC1,PPFIA3,ALDH4A1,ADAM23,SYNJ2,CACNA1I,LDLRAD4,BTRC,SOCS6,TPP1,DZIP3,SDC3,DCAF4,DCAF8,HDAC4,KBTBD11,DTNA,CAMSAP1,GLYR1,RAB30,MSL3,POLL,CNTRL,NR3C1,INPP5B,KCNN2,MIA2,KITLG,PALM,RETREG1,PLEC,PLTP,PLXNB1,PRKAB2,MAPK7,PTPRE,SELL,SLC1A7,PEX26,SMTN,FAM214B,SHANK2,ZCCHC24,IQSEC2,SLC44A1,SPHK2,DNALI1,SCG2,MARCH8,UBE3B" Drug 3849_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ASIC1,APBB2,APLP1,BRINP2,ALDH4A1,N4BP2L1,SLC16A4,SRSF11,NDST3,ZFYVE9,FADS2,CTIF,SHANK1,ATN1,EFNB3,EN2,SPEG,RASL12,FGF13,C1orf61,AGAP2,GPR153,SEPT9,GCNT2,SRCAP,C1QL1,GPER1,RAPGEF1,CELF3,IRF8,KHK,MMP16,CD200,NTRK2,NUMA1,CDK18,PDE3B,PTH1R,SEC61A2,ASAP3,ST6GAL1,ATP10B,INKA2,KANK1,GANAB,FAM168A,ARHGEF9,KAZN,TBCEL,TBL1X,ZEB1,TNS2,LAT2,ITM2C" Drug 5106_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "MTUS1,ALAD,ADAM15,CFLAR,LHX2,CLCN4,QKI,CREM,HAPLN1,DAPK3,EDIL3,FCF1,EFNA3,FAM13A,EGFR,MBNL2,STX2,ETV1,ZNF589,ANKFY1,PDLIM5,CSPG5,PNMA2,GART,GCNT2,GPD2,HSF2,IL6ST,INPP5B,KCNN1,MEF2C,PAK3,PIK3R1,STRN3,WDR25,ZNF671,SBF1,ZFP30,PPP1R9A,SLC14A1,ZKSCAN3,WDTC1,BEX1,SS18,NXT2,DICER1,TMPO,KLC2,ZBTB14,ZNF24,EVI5,MPPE1,PHTF2,SENP7" Drug 1507_DN Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "GAS7,FAM131A,PPFIA3,CDK10,ARHGDIG,SLC4A4,CDK5R1,SYNJ2,CAMK2G,QKI,FEZ1,SDC3,DCAF8,KIAA0586,DAPK3,GIT2,EGFR,IRAK4,PLEKHO1,ANKMY1,EZH1,F3,FAM49B,ATP2C1,RAB30,GNG4,DIDO1,RNFT2,INPP5B,MAP4,MBNL1,PDE3B,PIK3R1,PLEC,PLXNB1,MAPK8,TMEM104,RIPOR1,ATG16L1,TCP11L1,PPP4R3A,SPTAN1,CLSTN2,ASTN2,ATP11A,TNS2,CRTC1,AP4E1,TPD52,METTL3,WNK1,MAP3K12,EPM2A,ST7" Drug 6619_UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ARID1A,ADCY2,NLGN4X,PLA2G6,C1QTNF3,ANK2,APAF1,APBB2,ASCL1,ASTN1,ATP1A3,AZGP1,RUNX1T1,ARHGEF1,ARHGEF2,FOXN3,TCEAL2,ENTPD4,AKAP12,VCAN,SPOCK2,CHRDL1,DTNB,HEYL,CELSR3,FGF1,FGFR1,SORBS1,GPR19,GPER1,LSAMP,MGAT3,MMP16,CTNNA3,MYH3,OLR1,PENK,PFKFB4,PLXNB1,PPP2R2B,VPS13C,PTPRB,ZSCAN2,PID1,RFX2,TMEM206,SCN3A,SLC1A7,TNIK,ZHX3,PHLDB1,VLDLR,ZNF74,KCNAB1" Drug 5408_DN Ampicillin trihydrate [7177-48-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "NME5,MADD,BRINP2,ALDH7A1,KYAT1,SLIT2,CLU,QKI,CRY2,SIPA1L1,DCAF8,MFAP3L,MED24,MED12,ATN1,EFNA3,EGFR,FGFR1,BAIAP2,DPYSL4,OGA,ERAP1,INPP5K,GNG4,GPER1,GRIK5,FICD,ELOVL5,HNMT,INPP5B,NF1,KCTD15,MINDY2,PTCH1,PTHLH,ELOVL2,RAB3A,GTDC1,RGS12,KIF13A,RBM34,SPATA7,ZCCHC24,TROVE2,THSD1,ST5,INKA2,CEP68,KAZN,CABIN1,RUNDC3B,ZMYND8,SEMA3B,NUP214" Drug 5353_UP Fusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ARID1A,AP2A2,AK2,LTBP4,APC,APOC1,ATM,MTMR2,CACNA1I,CA4,CACNA1D,VAX2,CRY2,PDE4DIP,CDON,FEM1B,SRCAP,GLYR1,GNAO1,GNG3,PCLO,SOX21,HNMT,KCNJ3,LSS,MAN2A2,MAPT,ZNF862,NEK1,NOS1,PC,PLEC,POLG,CNNM2,TMEM104,RGS10,ARHGEF10L,TCP11L1,SH3BP2,SLC9A5,LIMCH1,RBM34,SOX2,EMC1,STX1A,ATP11A,TRIM2,PCDHA6,ZNF34,THRA,UBE2H,VAV2,GDPD5,MPPE1" Drug 2452_DN Vigabatrin [60643-86-9]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ADORA3,AP2A2,SRPX,ALK,AMH,AMPD3,SLC4A4,CFAP410,RAB33A,TJP2,ARHGEF10,DTNA,EFNA3,EFNB3,PLEKHA1,ING4,TNK2,C3orf18,CDKL3,CD320,ZNF589,CAMSAP1,FOXG1,AGAP2,GABRA2,ZNF276,POLL,NF1,NINJ2,PDE1C,PLCB2,PRKAR1B,MAPK10,ZCWPW1,RGS3,RGS10,EMID1,FOXRED2,SH3BP2,PEX26,EPN2,SLC11A1,IZUMO4,CAND2,DDN,KAZN,TCF7L2,TNS2,KAT6B,CDK20,SPHK2,ZNF142,REEP1,EVI5" Drug 3453_UP Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "RALGAPA1,ABHD6,PLA2G6,DOC2A,AMPD3,KCNAB2,APOC1,CFLAR,CA12,NEURL1,CDO1,ZFYVE9,ENTPD4,SH2B1,CNTNAP2,FAM169A,GREB1,ST8SIA3,EGFR,ZIC4,GPR153,SEPT9,USP19,RND1,GRM1,INPP5B,VWA5A,MSI1,PLXNB1,MBOAT7,GON4L,ELOVL2,KHDRBS2,SH3BP2,CCDC92,SMTN,FAM214B,SLC15A2,COA1,MAPKBP1,SOX3,ZHX3,ZBTB43,ATP10B,STXBP1,KIAA0930,PSD3,PCDHA5,CHST8,THRA,HEY2,TRO,ZIC3,REEP1" Drug 3431_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "ACTN2,NME5,PLA2G6,C1QTNF3,SPARCL1,SRPX,MRTFA,BEGAIN,DOC2A,PPFIA3,ATM,GYG2,CA4,FOXN3,STOML1,ARHGEF6,GREB1,ARHGAP32,DBT,DSCAM,TOM1,SORBS3,EML1,KIAA1109,IQCG,GAD1,DISC1,SRCAP,GLYR1,POLL,HNMT,HSD17B1,ITPKB,MDM4,MIA2,PDE3B,SSH1,RAB3IL1,RGS12,RXRA,ZNF821,FBXO11,SMTN,COA1,PHLDB1,JMJD6,PLCB1,IQCE,TK2,TMOD1,TNS1,PLPPR2,NSD2,ZIC3" Drug 5276_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.91E-05 9.35E-01 2.77E-04 3.16E-03 54 197 "DPF1,ACTN1,NDRG2,NME5,FAM131A,SLC2A11,BCL7A,SCAPER,CFAP410,CAMK2B,USP2,CHRNB2,CLTB,CRMP1,NCOR2,SDC3,GREB1,SMG7,RABGAP1L,ATN1,DYRK1A,EFNB3,ELAVL3,REEP2,DLC1,FOXG1,KHDRBS3,TBR1,GAD2,ATXN2L,MID1,NEK1,PIK3R1,PLCD1,TNPO2,PRKAB2,CCDC40,KLHDC8A,RYR1,ZNF821,RASA3,SH3BP2,SLC1A2,SLC1A7,CDK19,TCF7L2,SZT2,ARHGEF12,SF1,WNK1,SNX27,WIPF2,MVB12B,KAT6A" Drug CID000028112 lithium aluminum hydride Stitch 1.95E-05 9.58E-01 2.84E-04 3.23E-03 79 320 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,AGT,AQP4,AQP6,ATP1A2,ATP1A3,ATP6V0A1,CCK,SLC5A11,CHRM1,SLC22A6,CLU,SLC24A2,PLCXD3,HDAC9,PHF19,DRD1,ACTL6B,FOXO3,GAP43,GNAL,LOXL3,GRIA1,PLCD4,GRIN2C,GRIN2D,CIT,HTR2A,INPP1,MAOB,MAP2,MAPT,AQP11,MITF,NBL1,NEFM,NPY,NPPA,PDE4B,PDYN,PENK,PKM,PLCB2,PLCD1,PMP2,PRKCB,PRKCG,PKN2,PRKCZ,KLK6,RNH1,RORB,SCN3A,SCNN1D,SLC6A1,SLC6A11,SLC8A1,SNCA,SST,PLCB1,TCF4,TCF7L2,AZIN2,SYNE1,ICAM5,ACTR6,CABIN1,TRH,TRPC1,TRPC3,TRPM2,SLC13A3,SLC38A1,SLC17A7,NETO1" Drug 6874_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.97E-05 9.66E-01 2.86E-04 3.26E-03 51 183 "ABAT,ADRB2,EPB41L5,ARNTL,ST3GAL5,CHRNB2,CLU,PDE4DIP,CTH,KIAA0513,SPOCK3,F3,FDFT1,BAIAP2,PDLIM5,DISC1,C1QL1,RND1,GLS,GUCY1B1,KIF5C,VWA5A,MAP2,MAPT,MBD1,MMP16,PCBP3,PCDH9,SERPINI1,RETREG1,FSD1,PRPH,SYTL2,RGS4,ROM1,SH3GL3,FAM214B,SPTAN1,THSD1,CEP68,RGL1,ACSBG1,SYT11,VAMP1,SYT1,ATP11A,TNS1,UBE2H,PRDM2,SLC17A7,DPF3" Drug 2710_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.97E-05 9.66E-01 2.86E-04 3.26E-03 51 183 "NDRG2,ADD3,MTUS1,C1QTNF1,GAS7,DNAH17,ZSCAN18,ADGRB1,GYG2,CD86,CD38,CHN2,TAOK2,STOML1,CNTN1,CREM,ABCG1,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,KIAA0513,ZFYVE16,MAMLD1,FAM13A,ELAVL2,GALC,KCNJ4,KIT,VWA5A,MEF2C,SCAMP5,CD200,MX1,NPTX1,CEP41,PID1,KCTD17,PBRM1,ARHGEF40,KIF13A,TMCC1,CAND2,PEG10,DNMBP,PCDHGA10,CHST8,BEST1,ZBTB38,SLC30A3,PLSCR4" Drug CID000005618 U46619 Stitch 1.97E-05 9.68E-01 2.87E-04 3.26E-03 72 285 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1B,ADRB2,AGT,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CHRM1,MYL6B,PLCXD3,EDN1,EDN3,EDNRA,EDNRB,CACNG7,CALCRL,CACNG2,ACTL6B,MSTN,CRCP,HPGDS,PLCD4,GUCY1A2,GUCY1B1,PTGDR2,HTR2A,MYLK2,MYL3,NODAL,NOS1,NPY,NPR2,P2RY1,PDE1A,PDE1C,PDE3A,PDE3B,PDE1B,PKD1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,PTAFR,ACER3,RTKN,RYR1,RYR3,FNDC3A,PEG10,PLCB1,TAC1,TAC3,LEFTY2,HHIP,ACTR6,TMPO,P2RY12" Drug CID000005520 TPMPA Stitch 1.98E-05 9.70E-01 2.87E-04 3.27E-03 19 45 "BCS1L,SOCS6,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIK1,GRIK3,GRIK4,GRIK5,GRM5,PENK,EXOSC10,SLC1A7" Drug CID000003765 isoguvacine Stitch 1.98E-05 9.70E-01 2.87E-04 3.27E-03 19 45 "ABAT,DBI,CSPG5,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GLRB,GRIK1,NPY,SLC6A1,SLC6A11,SIRT2,SLC12A2,TACR1,TPM3,TRH" Drug ctd:C001277 geldanamycin CTD 1.99E-05 9.74E-01 2.88E-04 3.28E-03 89 371 "CLK4,OSBPL8,EPB41L5,MIER1,CASK,CDK13,DST,CDC27,HECTD1,NIPBL,RTTN,PDE4DIP,PYGO1,MATR3,ZC3H11A,PLPPR4,DMD,RCAN1,EDIL3,EDN1,SEMA3D,EGFR,MBNL2,ERBB2,FLT1,CAB39,ZMYND11,ARFIP1,CRCP,GLS,ZNF638,MAP4K5,RASSF8,KLF12,AGFG1,HSP90AA1,C5orf24,IL6ST,KCNH2,MBNL1,MMP16,SAMD5,SESN3,MYO5A,NASP,NF1,HCN1,DDR2,OXTR,CDK14,PIK3R1,ZNF655,MAPK3,PTHLH,PTK2,PTPRD,ZFHX4,KIRREL1,CLIP1,SFPQ,RUFY2,SLC8A1,BDP1,SP4,PEG10,RBM26,TROVE2,ITPRID2,LARP4,DIP2A,PRRC2C,EHBP1,FRYL,TLR4,ERCC6L2,TP53BP1,TPM4,NR2C2,TTC3,UBE2H,VLDLR,ZNF711,SLC38A1,EVI5,TUBA1A,KAT6A,PHTF2,CERS6,JMJD1C" Drug 6735_DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-05 1.00E+00 2.99E-04 3.40E-03 52 188 "CDC42BPA,PKP4,CDC14B,ASPH,STX16,SPAG9,CDC27,CHM,SLIT2,QKI,FAM169A,TBC1D5,DAPK3,DBT,EGFR,EIF4G1,WAC,CAP2,SPIN1,FERMT2,GPD2,PCLO,AGFG1,IFI16,IL6ST,MAP4,MBP,MYO6,NEK1,PDE1C,SSH1,RC3H2,PLEKHB2,RALGDS,ATG16L1,SLC25A36,AP1AR,SEC14L1,SON,PEG10,TROVE2,PRRC2C,TBL1X,TCF7L2,ZEB1,WASHC4,DICER1,KAT6B,USP1,SF1,ZNF24,PRDM2" Drug 5442_UP Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-05 1.00E+00 2.99E-04 3.40E-03 52 188 "C1QTNF1,MRTFA,GAS7,ATP2B3,N4BP2L1,ADGRB1,CACNB4,USP2,KCNAB3,ADGRG1,GREB1,DCAF4,SPOCK3,DPP6,ATN1,HIPK3,OPTN,EFNB3,EGFR,MTSS1L,AGAP2,B3GAT1,SYT17,LPAR4,GPER1,GRB10,SLC2A6,KCNMA1,MAP4,CEP41,PRKAR1B,ZCWPW1,GAL3ST4,RGS4,KLHL11,SALL1,SLC6A9,WDTC1,MYT1L,SOX2,IQSEC2,DDN,ATP10B,TAC3,MCF2L,ZEB1,TRIM2,SYNE1,ICAM5,PRMT8,SLC30A3,GDPD5" Drug 4410_DN Captopril [62571-86-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "NDRG2,AK2,PLA2G6,BIN1,ATM,CFLAR,MTMR3,LDLRAD4,NEURL1,ARHGEF2,TAOK2,LHX2,SPOCK2,CTIF,EGFR,DMTN,FOXG1,GPR153,GAB1,TRAF3IP2,HBS1L,TMEM8B,SEPT9,C1QL1,RUNDC3A,GNAL,TDRKH,STON1,IL6R,IL6ST,KCNN2,KCNQ3,NDUFA5,NEUROD1,NOS1,SERPINI1,RETREG1,PTHLH,PTN,RAD52,EMID1,KCNIP1,EPN2,SNCA,ZCCHC24,AJAP1,PLCB1,ARC,TBL1X,PCDHGA10,R3HDM1,HIRA,UPF3A" Drug 974_DN ikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ABHD6,DOC2A,APC,APP,ATP6V0A1,CDK5R1,EPS15L1,STOML1,HOMER3,ARHGEF6,AKAP7,COL4A5,SLC4A7,ENTPD4,AKAP12,MFAP3L,FBXL5,MAMLD1,HIPK3,RBM12,EIF5,PDLIM5,CGREF1,COPS8,RAB30,HSD17B1,HSF2,INPP5B,JAK2,KIF2A,MDM4,MPP2,ADAM22,LYRM9,CNOT4,SLC25A23,STRN3,TMEM104,RAD51D,MAP6D1,ABLIM3,ZHX3,TSPYL2,TROVE2,NXT2,PLCB1,AHCYL2,AP4E1,CADM1,PLPPR2,XRCC4,MAP3K12,PHTF2" Drug 3166_UP Clotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "KIDINS220,NME5,ABCD2,APP,ATP1A3,ADAM23,SCAPER,MTMR3,CACNA1D,CNN3,CRYBB1,AATK,NOS1AP,RASSF2,C2CD2L,SLC12A6,DTNA,DUSP9,C3orf18,DLC1,AGAP2,HBS1L,SRCAP,RUNDC3A,GRIK2,NR3C1,JAK2,KCNJ5,KCNMA1,MITF,BCO1,MSR1,NPPA,GPR85,PTHLH,RAB3IL1,RGS12,RPS6KA2,TRIM46,SH3BP2,SLC2A5,SLC6A8,ARHGAP26,MAPK8IP3,AJAP1,TRIM2,CDK20,AMOT,UGT8,VAV2,WIPF1,XRCC4,SEMA3B" Drug 7548_UP DNA-PK Inhibitor III; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ASIC1,ADCY6,ALDH4A1,MPDZ,BAIAP3,FOXN3,TAOK2,RAB28,CLU,CRY2,ABCG1,CTH,CTNND2,DAPK3,SGSM2,DPH1,SEMA3D,OPTN,DMTN,STX2,ERCC2,DLC1,FGF13,FGFR1,BAIAP2,TRMO,PDLIM5,CSPG5,GPR19,KLF12,HNMT,ITPKA,MBD1,NDUFA5,NPPA,SAMD9,ELOVL2,PTN,FAM120C,SUGCT,ZNF671,CSRNP3,SCG5,ASAP3,MYH15,RIMS1,SNCA,SPATA7,KIAA1107,TK2,FLRT1,HPS4,PCBP4" Drug 1301_UP Domperidone maleate; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "NDRG3,APBB2,STX16,ST3GAL5,SCARB1,CLGN,SRSF11,STOML1,QKI,AKAP7,ARMC8,CREM,CSNK1E,DZIP3,CTH,FCF1,FAM13A,COQ7,OGA,GPR19,LIG4,MAP4,MEST,MPP2,N6AMT1,NEK1,PIK3R1,CCSER2,MINDY2,MAPK8,SIDT1,PTAFR,RIPOR1,RET,SBF1,FERMT1,FBXO11,ELMO2,WDTC1,EMC1,BEX1,THSD1,LARP4,SS18,NXT2,VAMP1,ATP11A,KAZN,FBXW11,ZEB1,CRTC1,ZNF34,ZBTB38" Drug 2093_UP Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ABAT,ACHE,ACTN2,PLA2G6,STX16,ATP2A2,SYNJ2,SCAPER,CBFA2T2,ARHGAP22,CLCN3,ENTPD4,SEC14L5,SPOCK3,DPH1,DSCAM,EDN3,FCF1,ANKMY1,KIAA1109,FGF1,DLL3,FYB1,SYT17,CRCP,SPIN1,LPAR4,ADAMTS6,MMP16,GIT1,ADAM22,TAGLN3,NF1,CNOT4,PBX1,KCTD15,CNTLN,RIPOR1,C1orf54,ZCWPW1,KIRREL1,WDTC1,ZBTB43,DDN,ASTN2,EHBP1,TCF4,TCF7L2,SYNE1,PSD3,LAT2,PRDM2,NUP214" Drug 4835_UP Nifuroxazide [965-52-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "NME5,RGS20,CADM3,SYNJ2,MTMR3,BAIAP3,HAP1,CBFA2T2,ARHGEF2,CLGN,CLCN4,CLU,QKI,NECTIN3,CREM,CYBB,ARMCX2,FBXL5,EGR3,COQ7,RASGRP2,SPEG,AGAP2,PDLIM5,FYN,DISC1,GATM,GRB10,GRIN1,GRM1,CELF3,ATXN2L,LMO2,VWA5A,MDM4,MID1,CDK14,SERPINI1,PIK3CD,MAPK7,PTHLH,RPS6KA2,CCDC88A,ARC,EXOC7,RPGRIP1L,PCDHA6,AP4E1,MICAL1,VLDLR,XRCC4,SLC30A3,WNK1" Drug 3677_DN Salbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ABR,ACTN1,ADRB2,APP,CDC14B,SEMA4G,CDK13,NUMB,MYRF,HAP1,RCBTB2,SOCS6,PLEKHB1,NRXN3,NMT2,NIPBL,HOMER3,CNTFR,CREM,APPL1,HDAC9,TOX,MFAP3L,PLPPR4,SGSM2,SPEG,FGF1,CGREF1,OGA,GBX2,GLRB,GNG4,TJAP1,INPP5B,KCNJ5,SMAD1,MBNL1,NF1,OCRL,RAB3IL1,GTDC1,CLIP1,ZNF667,KIF13A,ARHGAP26,SRPK2,PHLDB1,SYT11,TCF4,TNS1,RUNDC3B,NSD2,EVI5" Drug 6898_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "APAF1,APP,ZBTB10,ATM,STX16,BCL2L2,RAB29,KYAT1,CDC27,CDH18,VAX2,SLC4A7,CREM,SH2B1,SOCS5,DCAF8,RIMS3,DNAJC6,LYPD1,RABGAP1L,EML1,LRRC23,BAIAP2,MPP6,OGA,SRCAP,MALT1,POLL,KCNN1,KHK,NEK1,NFYA,NUMA1,RAD52,FOXRED2,SUPT20H,FBXO11,ZNF365,PPP4R3A,BTBD7,EMC1,SPART,LHPP,TRIM2,RPRM,VGF,XRCC4,ZFP37,ZNF24,WNK1,MAP3K12,HPS4,SSPN" Drug 262_UP "indomethacin, USP; Up 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ASIC1,KDM5D,ARID1A,BRAP,KCNAB2,ARNTL,ATM,CACNA1I,CHGA,TAOK2,TPP1,PCYT1B,CSF1R,DCAF8,EFNB3,TNK2,ERCC2,EYA1,ZIC4,TRMO,NSG2,SEPT9,SOX21,FAM107A,ARHGAP19,ATXN2L,HLF,IRF8,L1CAM,ADAM22,NF1,NNAT,NOS1,NTRK2,OPCML,EPN1,STRN3,MBOAT7,MED1,RAB3A,FNDC3A,PPP4R3A,FAM214B,SLC11A1,SLCO1A2,IFT122,PHLDB1,TCF7L2,TEK,TPD52,TRIO,PLPPR2,WNT7A" Drug 4380_DN CP-690334-01 [459212-38-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "ASIC1,BRAP,PLA2G6,AMPD3,CDC42BPA,APLP1,SEMA4G,RGS20,ATM,CFLAR,GYG2,CACNA1I,CDC42,CDH18,CHRNB2,CNTFR,WHRN,CPS1,AKAP12,ABCG1,CSF1,MFAP3L,RUSC2,DMPK,HIPK3,EPB41L1,LRRC23,GPR153,PCDH17,RND1,BTN2A1,ICA1,BRINP3,ITPKB,KHK,KIT,NPTX1,NLE1,POU3F2,PRODH,LRRC49,RIPOR1,TRIM68,IL17RB,LIMCH1,INKA2,POPDC3,TCF7,PCDHA6,DAAM2,PARD3,ZMYND8,EVI5" Drug 7392_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "DPF1,RALGAPA1,CLK4,GRAMD1B,PKP4,KCNAB2,APC,BTRC,KYAT1,CBFA2T2,SCARB1,CACNA2D2,PLEKHB1,WHRN,CRY2,CTH,RIMS3,ATN1,CNNM1,EFNA3,FAM13A,DMTN,ETV1,RRAGB,RACK1,ATP2C1,ERAP1,ZNF276,GLYR1,GPER1,ATXN2L,TJAP1,KCNMA1,CNOT4,CLDN11,SMIM7,MINDY2,PTPRE,FAM120C,TMEM231,FBXW7,CSRNP3,SUPT20H,ST6GAL1,BCAN,TMCC1,SPTAN1,ST5,JMJD6,ZNF34,CABIN1,ZKSCAN5,PRDM2" Drug 6760_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.15E-05 1.00E+00 3.10E-04 3.53E-03 53 193 "AP2A2,APAF1,BCAS1,B3GALT2,NRP2,IL33,MAP7,SCARB1,TAOK2,ABCG2,RGS6,SEC14L5,MFAP3L,ARNT2,DUSP9,ING4,F5,TUBB4A,FGF1,GNG3,CNTRL,GRM7,GRM8,GUCY1A2,ELOVL5,SHISAL1,KIT,ADAM11,MSI1,ADAM22,MX1,PDE4B,GPR85,PHKG1,SLC25A23,PTHLH,PTPRH,ROM1,IL17RB,ZFP30,HECW1,IQSEC2,NCDN,DNAH7,DAAM2,R3HDM1,SEZ6L,TRPC3,SLC30A4,EMSY,PRDM2,PARP6,EPM2A" Drug CID000441452 methylenecyclopropylglycine Stitch 2.20E-05 1.00E+00 3.13E-04 3.56E-03 20 49 "ABR,ADORA1,ASPA,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MBD1,SALL1,SLC1A7" Drug 4248_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.21E-05 1.00E+00 3.13E-04 3.56E-03 50 179 "DPF1,NME5,APAF1,MARK4,IL33,CACNG1,HAP1,MAP7,RUNX1T1,CNTFR,CREM,SLITRK5,PHF14,CTH,RIMS2,RIPOR2,MAML1,DGKG,PITPNC1,DTNA,EDNRA,HIPK3,ZNF391,NRN1,ABCA8,PTK2B,TRMO,TACC2,NEU3,IL6ST,ITIH2,MDM4,NF1,NNAT,PDE4B,PDE4D,PDGFRA,SMOX,PRODH,PTHLH,RGS3,KCNIP1,CSRNP3,ZNF334,SLC15A2,ZC3H13,TBL1X,ZFPM2,TNS1,ZMYND8" Drug 6045_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.21E-05 1.00E+00 3.13E-04 3.56E-03 50 179 "ACTN2,AMPD3,CDC42BPA,APC,ASTN1,ATP2B2,ALDH7A1,RGS9,DLGAP1,SULT4A1,COL9A3,SH2B1,HAPLN1,SPOCK3,EXOG,ECM2,DYRK1A,HEYL,MBNL2,CAMKK2,FYN,GAP43,ERAP1,CSDC2,ATF7,GRB10,ADAMTS8,HAS2,HRH3,ATXN2L,KLF12,SYNPO,KCNJ4,MAG,ADAM22,NHLH1,CAMKV,PLTP,PMP2,PTH1R,C1orf54,ZMAT4,SOX15,ZEB1,TRIM2,PCDHGA10,DOCK9,ZNF711,MVB12B,KAT6A" Drug 4452_UP geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.21E-05 1.00E+00 3.13E-04 3.56E-03 50 179 "ACTN2,GRAMD1B,ADRA1D,CBS,ARHGEF2,ABI3BP,CRY2,PDE4DIP,CTH,EDRF1,PHYHIP,ZNF804A,SMG7,SPOCK3,TRAPPC9,EDN1,F5,REEP2,FOXG1,ELOVL5,KCNH2,VWA5A,MATN3,MMP16,NUCB1,OXTR,TREM2,PALM,PDE4B,PDE4D,MBOAT7,POU6F1,PRKCZ,MAPK8,PTHLH,MARCH1,RGS4,TTLL7,TCP11L1,HSPA4L,FRMPD1,DZIP1,SNAP25,RBM34,PDZD2,NFASC,SYNE1,WIPF1,SF1,ZIC3" Drug 2136_UP Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 47 165 "MTUS1,BIN1,GAS7,DNAH17,CD86,CD38,CHN2,CLCN4,CREM,SIPA1L1,VCAN,PDE4DIP,PPP1R16B,DOCK4,KIAA0513,GSDME,FAM13A,PLXNC1,LRRC23,OLFM1,BAIAP2,PRKAG2,TRAF3IP2,ICA1,ITGAV,VWA5A,MEF2C,LYRM9,ZNF862,OLR1,PDE4A,PDE4B,PRKCZ,SGK1,ARHGEF40,ZCCHC24,ZHX3,SPTAN1,TSPYL2,EPB41L3,MAPK8IP3,PLCB1,CAMSAP2,ICAM5,RUNDC3B,FLRT2,CLIP2" Drug 7554_DN ST021200; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AK2,CAPRIN2,SYNJ2,BAIAP3,CBFA2T2,JAM2,RAB33A,ZFYVE9,VAX2,HOMER3,CRY2,NCOR2,SMG7,DTNA,EPB41L1,ZNF589,FGF12,CAMSAP1,FOXG1,AHDC1,GLS,GNG4,MAP4K5,TJAP1,KCNN1,MIA2,AFDN,MSI1,ZNF862,PBX1,LRP12,PACSIN1,PRKAR1B,PEX5,RAB3A,RAB3IL1,MYH14,TCP11L1,WLS,SIRT2,BTBD7,ZKSCAN3,SNCA,SP4,NCDN,ANKRD12,TPM1,HIRA,VIPR2,ZNF74,SLC26A10,EVI5,NUP214,SSPN" Drug 3883_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP2A2,NME5,MRTFA,BIN1,CDK13,SLC2A11,ARHGEF7,HIP1R,KYAT1,ARHGEF1,CBFA2T2,ARHGEF2,LHX2,USP6NL,EDRF1,ATN1,DSCAM,DTNA,KAT8,SCARA3,DLL3,GCNT2,RUNDC3A,RND1,GPER1,ATXN2L,JAK2,KCNJ3,KHK,MAOB,MAP2,MMP17,ADAM22,NPPA,PLCD1,TNPO2,PTHLH,RAB3A,CCDC40,SH3BP2,SMARCD3,ZCCHC24,ST5,PLCB1,ARHGEF12,CRTC1,SLC44A1,HEY1,FAM155A,VIPR2,KCNK12,SYNC,FIP1L1,ITM2C" Drug 842_UP "N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG2,ALAD,EPB41L5,PPFIA3,ARHGDIG,PDE8B,CADM3,ADGRB2,CFLAR,ST3GAL5,BAIAP3,NMT2,COL9A2,BAG4,CTH,BRINP1,DBT,MFAP3L,SLC12A6,SUGP2,F3,KIAA1109,SRCAP,CNTRL,SPACA9,RNFT2,TJAP1,INPP5B,KCND3,LIG4,LYRM9,NF1,OXTR,PIK3CD,PRPH,RAB3A,RAB3IL1,SAFB,SLC15A2,BTBD7,SLC20A2,ZBTB43,THSD1,CEP68,DIP2A,PLCB1,TACC1,SZT2,AHCYL2,ZKSCAN5,UBTF,SH3GLB2,WNK1,SSPN" Drug 6100_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SLC12A5,AMPD3,AMPH,FAM131A,APP,ALDH4A1,ADAM23,BTRC,CA12,CBFA2T2,NEURL1,CSF1R,CTH,RIMS2,MAML1,ZNF804A,RUSC2,FEM1B,EFNA3,C3orf18,DLC1,ZNF589,FGFR1,FHL1,RAB30,GNAS,GNG4,INPP5B,ITIH2,IPO5,MAP4,MMP16,MOBP,ADAM22,GPR85,PLCD1,PRKAR1B,GRAMD1C,WDR25,RIPOR1,ZSCAN2,GTDC1,RGS12,FBXO11,PEX26,SNCA,ZCCHC24,SYN2,KAZN,WIPF1,ZFP37,ZNF711,ZNF45,TFIP11" Drug 7017_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP2A2,ALCAM,CDK13,SCAPER,BAIAP3,BTRC,CBFA2T2,CHM,ARHGEF10,SOCS5,RASSF2,INTS1,ARMCX2,ATN1,DTNA,CDKL3,FECH,BAIAP2,FHL1,SEMA4D,GABRA2,GAD1,TXNL4A,RAB40B,GPM6A,SPACA9,HLF,ELOVL5,INPP5B,KCNF1,IPO5,LAMA2,MMP16,GIT1,MSR1,LYRM9,CNOT4,SETD4,PDE3B,CNNM2,RAB3IL1,RGS3,GSTCD,FBXW7,FBXO11,SLC20A2,SNCA,LHPP,PCDHGA10,TMOD1,R3HDM1,ZMYND8,ZBTB14,PHTF2" Drug 3364_DN Acetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,APOC1,ATM,CFLAR,SYNJ2,SCAPER,DNAJB5,RCHY1,ENTPD4,NOS1AP,TBC1D5,DMPK,ATN1,LRRC23,SPEG,F3,ACSL4,IQCG,PRELID3A,OGA,SRCAP,IL6ST,INPP5B,JAK2,SMAD1,MPP2,ADAM22,CDK18,RETREG1,LRP12,GON4L,PTPRO,RGS10,CLIP1,RASA3,SMTN,SLC22A4,RBM34,IQSEC2,TBCEL,SMG6,TCF7,PCDHA6,BHLHB9,MICAL1,WIPF1,KLC2,ZFP37,ZNF24,SPHK2,REEP1,WNK1,EMSY,HPS4" Drug 1493_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP2A2,SRPX,ALK,MRTFA,AMH,BIN1,CDC42BPA,APC,SEMA4G,SLC4A4,SCAPER,MTMR2,CAMK2B,KYAT1,TAOK2,CRMP1,RUSC2,TRAPPC9,SHANK1,EIF4G2,MRNIP,DLC1,FGFR1,ANKFY1,EFCAB2,PDLIM5,ALDH1L1,GNAS,GPER1,INPP5B,KCNH2,MBD1,NACA,LRP12,MINDY2,PPP2R2B,PRKAR1B,PTAFR,RAB3A,SEMA6D,SLC22A4,KAZN,IQCE,CRTC1,CHST8,TMOD1,CABIN1,PIK3R5,CDK20,TPM3,WIPF1,ZNF45,KAT6A,SENP7" Drug 2809_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ABR,AP2A2,MARK4,ALDH4A1,CFLAR,KYAT1,KRIT1,USP2,SYNGR3,PLEKHB1,ZFYVE9,DZIP3,LYPD1,SMG7,RABGAP1L,MED12,SIDT2,EGR3,ERBB2,EZH1,FGFR1,IQCG,ATP2C1,TXNL4A,GLYR1,STON1,IL6ST,KCNH2,MAP4,MPP2,NEK1,PLEC,SLC25A23,MBOAT7,PTK2,RIPOR1,QDPR,RALGDS,RGS10,ITSN1,PEX26,PDZRN3,ZCCHC24,ZBTB43,MTCL1,AHCYL2,TIAM1,PARD3,CDK20,HIRA,KCNK12,GDPD5,NAV2,PCBP4" Drug 4183_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACHE,SPARCL1,DOC2A,BIN1,PPP4R4,ZSCAN18,FUBP1,CACNA2D1,CACNG1,LDB2,LARGE1,EPS15L1,VAX2,DNAJB5,HOMER3,AKAP5,CYBB,AK5,SPEG,CORO2B,PDLIM5,B3GAT1,ATP8A2,RUNDC3A,GSTM5,AP4S1,KLF12,HTR5A,ICA1,IGFBP1,MMP16,MSR1,MX1,LYRM9,NTRK2,OLR1,PENK,MTRF1L,ZSCAN32,GAL3ST4,RGS12,PNMA8A,TMEM206,RPS6KA2,IZUMO4,CAND2,CDK19,TBCEL,TNS1,CHST5,NSD2,WNK1,PARP6,KCNAB1" Drug 7520_UP Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,BEGAIN,APBB1,CDC14B,BRINP2,ALDH4A1,OSGIN2,CFAP410,PLEKHB1,NMT2,HAPLN1,CSF1,CSNK1E,PDE4DIP,MAML1,DAPK3,C2CD2L,KLHL3,DTNA,EN2,VPS13B,DMTN,KAT8,BAIAP2,SCARA3,PDLIM5,CGREF1,GAD1,TMEM8B,BTN2A1,ATXN2L,KLF12,SCIN,MIA2,MMP17,ZNF862,PCSK2,CDK18,PRPH,APTX,RAB3A,CCDC40,RAD52,MAPK12,STUM,ASAP3,SLC20A2,VAMP1,FBXW11,TRIM2,TRIO,PRDM2,NT5M,PCBP4" Drug 6388_DN Orlistat; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASPHD1,ADD2,BIN1,APBA2,APC,APP,MTMR9,BMP7,HAP1,CAMK2B,CHM,CLCN4,RAB26,CRMP1,PDE4DIP,SEC14L5,GPRASP1,RIMS3,CNIH3,ECM2,TNK2,GCNT2,SRCAP,GHR,GPD2,BACH2,IFI16,LMO2,MEF2C,MT1M,LYRM9,ODF2,PGAM2,MAPK10,CNNM2,PTPRD,RAB3IL1,ZFP30,FBXO11,SLA,PEX26,EPN2,CCDC88A,TSNAXIP1,KDM4C,KIAA0930,OBSL1,GPR161,BEX4,TPM1,CDK20,SPHK2,PARP6,HPS4" Drug 1497_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,C1QTNF3,SRPX,APLP1,PLA2G4C,MARK4,ATM,NRP2,HAP1,CAMK2A,CCK,DCLK1,CLU,IFFO1,CPS1,HAPLN1,GREB1,EIF4G2,ERCC2,ZNF589,CSPG5,HBS1L,RUNDC3A,RAB30,GNG3,NR3C1,RASSF8,INPP5B,KCNH2,MMP16,MYO7A,CLDN11,SERPINE2,PIK3CD,SEPT4,MAPK8,RAB3A,CEP97,RALGDS,C1orf54,RPS6KA2,PPP4R3A,SLC15A2,COA1,RPGRIP1L,CHST8,PIK3R5,TRPC1,FAM155A,KCNK12,NDRG4,NT5M,NUP214,RNF170" Drug 2246_DN Isoniazid [54-85-3]; Down 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG2,APC,BCAS1,CDK13,MARK4,ALDH4A1,CFAP410,CA4,ARHGAP33,HOMER3,AKAP7,ARMC8,ENTPD4,ARHGEF4,PPP6R2,TBC1D5,HP1BP3,DSCAM,EFNB3,KAT8,ZNF589,HBS1L,GLYR1,GNG4,GPER1,GRB10,ICA1,ITPKB,KCNJ3,LSS,MAP4,KITLG,NFYA,NPTX1,PIK3CD,STRN3,TMEM104,RAB3IL1,ZDHHC14,RGS10,ROM1,ABLIM3,EPN2,SLC22A4,SMARCA4,CDK5RAP2,STX1A,TCF7,TCF7L2,VAV2,EMSY,PRDM2,SEMA3B,UBE3B" Drug 4214_UP Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,ARID1A,KLRC4,BIN1,PPFIA3,N4BP2L1,KSR1,CACNA2D1,NGB,SCARB1,LARGE1,TAOK2,VAX2,HOMER3,NCOR2,CDON,ATN1,PLXNC1,IRAK4,NCALD,IGSF6,CORO2B,PDLIM5,GABRA2,SRCAP,GFER,GLYR1,ICA1,KCNJ5,KIT,VWA5A,SMAD1,ADAM22,MSR1,NF1,NUCB1,NUMA1,PALM,PDE4B,RASGRF1,KCNIP1,LRRTM4,SLCO1A2,SNCA,KIF13A,DOK5,ZHX3,IZUMO4,ZC3H13,MAPK8IP3,ACSBG1,PCDHA5,VAV2,SLC17A7" Drug 5793_DN Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP2A2,ALDH4A1,ZFYVE9,KIAA1549L,NMT2,ARHGEF6,CPS1,CSF1,PDE4DIP,DBN1,C2CD2L,HIPK3,ACSL4,BAIAP2,CINP,GAD1,TMEM8B,DISC1,GPM6B,GSN,TJAP1,MATN3,MT1M,ZNF862,NF1,NUMA1,PFKFB3,NLE1,RC3H2,MINDY2,ELOVL2,PTN,RIPOR1,TMEM231,BEND5,KIRREL1,ITSN1,AMBRA1,BTBD7,KDM4B,ZBTB43,LHPP,TROVE2,MAPK8IP3,ARHGEF9,SYT1,MCF2L,TCF4,TCF7L2,TIAM1,TK2,WNT7A,NT5M,GAN" Drug 6360_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "PPP4R4,ASCL1,MARCH3,ALDH4A1,CFLAR,ST3GAL5,CACNA1I,CHRNB2,NRXN3,CREM,ABCG1,SUSD5,CTNND2,RIPOR2,RIMS3,CDON,DTNA,EDIL3,EFNB3,VPS26C,ATP8A1,SORBS1,FYB1,DISC1,ALDH1L1,GLYR1,GLRB,ITIH2,KHK,MX1,NDUFA5,NUMA1,PDE4A,PLCD1,C19orf57,MAPK8,GRAMD1C,WDR25,PTPRH,RPS6KA2,CNKSR2,DZIP1,SLC1A7,SLC2A5,ZNF334,IFT122,LIMCH1,ADGRL3,ARHGEF12,THRA,PIK3R5,TRPC1,XRCC4,JPH3" Drug 3618_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "KCNAB2,FAM131A,KIF1A,PICK1,CNTNAP2,DBN1,DMPK,EFNA3,SORBS3,OGA,GAD1,B4GALNT1,SYT17,INPP5K,GLYR1,MSL3,POLL,GNAS,GNG3,CNTRL,GSN,INPP5B,MMP16,MMP17,MPP2,NOS1,SERPINI1,LRP12,PRKAR1B,LRRC49,PTHLH,PTPRO,ZDHHC14,RGS10,SH3BP2,FBXO11,FAM214B,BTBD7,SLN,WDTC1,SOX2,ZHX3,EMC1,KDM4C,ZC3H13,KIAA1107,SLC44A1,TMOD1,ZMYND8,ZKSCAN5,FAM155A,ZFP37,MPPE1,KAT6A" Drug 4789_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NME5,ALCAM,CDC42BPA,KCNAB2,APOC1,CDK13,ATP6V0A1,CACNA1I,LDLRAD4,BTRC,CALB2,CDO1,RAB28,TPP1,NECTIN3,CPS1,CRMP1,SNX29,EFNA3,MBNL2,CALCRL,EPB41L1,PTK2B,DLC1,FGF13,GPR153,GCNT2,GPM6B,LPAR4,GPER1,KCNJ3,KCNQ3,MYT1,PALM,PCDH9,EPN1,GRAMD1C,NKAIN1,EMID1,WLS,ZNF821,PREX2,CXXC4,SNCA,ZC3H13,ARHGAP26,POPDC3,TBL1X,PSD3,CRTC1,SEZ6L,WNK1,KCNAB1,ST7" Drug 3450_UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AK2,KCNAB2,APBB2,GAS7,APLP1,PPFIA3,ATM,ATP6V0A1,GYG2,CACNB2,USP2,CACNA2D2,SRSF11,CHM,CLCN3,SH2B1,JAKMIP2,MFAP3L,GNE,SUGP2,C3orf18,ZNF589,FGFR1,FOXG1,SEMA4D,ATP8A2,SRCAP,GLS,GPD1,DIDO1,HNMT,KCNH2,MAP4,NFYA,NTRK2,NUMA1,MINDY2,PPP5C,PRKAR1B,MYH14,FAM214B,COA1,SPTAN1,CDK19,ZBTB43,ATP10B,PLCB1,POPDC3,TCF7L2,TMEM151B,TRIO,ZMYND8,SLC30A3,KCNAB1" Drug 3639_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "LTBP4,BEGAIN,BIN1,APBA2,SEMA4G,SLC2A11,KIF1A,NRP2,CFLAR,BAIAP3,CACNA1A,SLC16A4,LRRFIP1,CRLF1,SLIT2,FADS2,VAX2,AKAP7,AKAP5,CRY2,SNCAIP,PDE4DIP,SDC3,CYBB,PLEKHO1,CGREF1,GAD1,ADAMTS13,KCNMA1,SMAD1,MAP2,MATN3,MMP17,NF1,NPTX2,CDK18,PIK3CD,MAPK8,RELN,PTPRO,ZSCAN2,GSTCD,CPEB3,CXXC4,SPTAN1,SPTB,ATP11A,KIAA0930,DOCK9,PCDHA5,SLC35G2,CHST8,FLRT2,ZIC3" Drug 4315_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADD2,FAM135A,APAF1,ARRB1,CDK13,PTCH2,ADAM15,FUBP1,BAIAP3,NEURL1,ADGRG1,NRXN3,TPP1,IFFO1,SH2B1,ABCG1,EDRF1,CYBB,DAPK1,CTIF,DSCAM,DTNA,AASS,TENM1,PRELID3A,GDF9,RND1,LILRB4,GRK4,PTPRT,IL1RAPL1,ICA1,KCND2,NCAM1,NCAM2,NUMA1,PBX1,PDE4A,PTPRN2,CCDC40,RASGRF1,RFX2,TMEM206,RYR3,NTNG1,SLC6A9,OGDHL,DOP1A,IQSEC2,SSTR1,TPM3,UCHL1,LAT2,MVB12B" Drug 2069_DN Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "C1QTNF1,AMPD3,AMT,KCNAB2,APOC1,ATM,ST3GAL5,ZFYVE9,SMARCAL1,PPP6R2,PARD6A,SGSM2,TRAPPC9,SUGP2,WAC,ZNF589,FGFR1,CINP,FAM49B,DLL3,GAD1,SRCAP,ZNF276,COPS8,PRRC2B,GPER1,SYNPO,ICA1,ZNF862,SETD4,ODF2,OGG1,RAB3A,ARHGEF10L,SUGCT,DCUN1D2,RPS6KA2,ATXN2,SH3BP2,SLC1A3,LIMS2,SIRT2,BTBD7,CDK5RAP2,SPTAN1,TIMP4,TK2,LMF1,TFIP11,UPF3A,PRDM2,NT5M,WIPF2,AAAS" Drug 3567_UP Piretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SYN3,TKTL1,PLA2G6,ALCAM,KCNAB2,APC,ARNTL,SLC4A4,SLC2A11,ATP6V0A1,RGS9,CLDN10,CBFA2T2,ARHGAP33,HOMER3,CSF1R,SDC3,RIMS2,FAM131B,SEC14L5,RIMS3,MFAP3L,HIPK3,C3orf18,ERCC2,ZNF589,GABRA2,GAD1,ERAP1,RND1,GLS,GPER1,ADAMTS13,VWA5A,KITLG,NFYA,CNOT4,PC,PDE1C,SLC25A23,CNNM2,PLPPR1,RGS12,KCTD17,CPEB3,CXXC4,SOX2,AJAP1,JMJD6,VPS13A,FLRT2,LAT2,UBE3B,SENP7" Drug 2264_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASPHD1,NDRG2,SPARCL1,MRTFA,AMPD3,ASCL1,MARK4,ATP2B2,BACH1,RUNX1T1,CBFA2T2,CLGN,PLEKHB1,ZFYVE9,WHRN,COL9A3,NECTIN3,PARD6A,SRGAP3,GNE,DYRK1A,EDN1,EDNRB,VPS13B,STX2,CDKL3,TUBB4A,SEPT9,NR3C1,GRM2,IL6R,ITIH2,KCND3,KIF5A,KPNA5,MAG,NPY,PLCB2,PNMA3,PMP22,MINDY2,PTCH1,CCDC40,ZFHX4,SCN2B,CCDC88A,SOX2,WSCD1,ZEB1,PSD3,R3HDM1,TNS1,FLRT2,XRCC4" Drug 1288_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG3,PLA2G6,APBB2,CASK,SLC4A4,BCL2L2,CFAP410,CAMK2B,ARHGAP33,RAB33A,FADS2,DNAJB5,CSF1,C2CD2L,CDON,C3orf18,COQ7,PIPOX,PTK2B,FHL1,AGAP2,CGREF1,LILRA2,KCND1,LSS,MAP4,MX1,NRCAM,CCSER2,SLC25A23,RC3H2,CEP41,MASP1,RAB3IL1,RAP1GAP,KCTD17,SCG5,FAM102A,FBXO11,ARFGAP1,DOK5,ZC4H2,MAPK8IP3,FAM168A,ADGRL3,SIN3B,PSD3,CRTC1,ATP13A2,TGFBR3,ZNF34,KCTD2,RPRM,ZNF45" Drug 7497_UP CP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASPHD1,KIAA1324,AK2,LTBP4,CDC42BPA,GAS7,APLP1,PPFIA3,CFLAR,FUBP1,MTMR2,GYG2,CAMK2B,CREM,PDE4DIP,RIMS2,DMPK,DNM2,FEM1B,EFNB3,CELSR3,EIF5,REEP2,BAIAP2,COPS8,SLC2A6,NXPH3,MGAT3,NEK1,CDK18,NECAB2,CNNM2,PTCH1,RALGDS,RGS12,KCTD17,EMID1,ZNF821,SYBU,BTBD7,SLC22A4,ZCCHC24,UNC5B,IQSEC2,CDK19,VAMP1,TACC1,EXOC7,CRTC1,PARD3,TRIO,PLPPR2,ZBTB14,MAP3K12" Drug 2815_UP Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DNAH17,SLC4A4,CDC42,CACNA2D2,RCBTB2,CHN2,TAOK2,ARHGEF6,NECTIN3,SH2B1,CRMP1,NOS1AP,SGSM2,SGK2,TNK2,DMTN,STX2,ZNF589,OGA,GLS,TJAP1,KCNF1,MAP4,ADAM22,NDUFA5,CLDN11,PCDH9,CDK18,PENK,PLCD1,PRODH,RELN,PTHLH,PTN,RAB3A,RAB3IL1,RGS10,EMID1,SYNDIG1,SH3BP2,SH3GL3,SHANK2,ZBTB43,ST5,ARC,ATP11A,KIAA1107,WSCD1,PCDHA5,CABIN1,PLPPR2,DNALI1,SEMA3B,ITM2C" Drug 4235_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADD2,SLC12A5,ADORA2A,ALK,APBB1,NOL4,ATP6V0A1,ST3GAL5,CFAP410,CACNA2D1,RUNX1T1,CHI3L2,VAX2,CNTFR,CNTNAP2,CYBB,RIPOR2,RIMS3,SPOCK3,HIPK3,LRRC17,EPHB1,PIPOX,PTK2B,KIAA1109,FGF1,FGF12,CAMSAP1,GAB1,GAD2,NEU3,TDRKH,LILRA2,STON1,GUCY1B1,LAMA2,SHC3,MOBP,NRCAM,NTRK2,PDE3B,CAMKV,PTN,PTPRN2,PAQR6,KCNIP1,TRIM46,SLC2A5,PDZRN3,SPTB,MCF2L,RALYL,TNS1,DPF3" Drug 4698_UP Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,ASIC1,NDRG2,ADORA1,SEMA4G,PDE8B,ADAM15,AZGP1,CFLAR,CHRNB2,QKI,EDRF1,TBC1D5,MAML1,HP1BP3,GNE,EDNRA,SIDT2,EFNA3,EN2,RASGRP2,NCALD,CEND1,PTK2B,KIAA1109,CAMSAP1,IQCG,FLNC,DCTN2,GALC,SRCAP,MALT1,GLYR1,TDRKH,GSTM5,IL6ST,INPP1,KCNMA1,LIG4,MMP16,PLCD1,LRP12,PPP2R2B,MAPK7,CNNM2,SNRK,PTHLH,RGS12,ROM1,ASAP3,DMXL2,PCDHA6,WNK1,SEMA3B" Drug 2910_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "PLA2G6,PPP4R4,ASPH,ALDH4A1,ATP6V0A1,MYRF,LDLRAD4,CDH10,STOML1,COL9A3,CREM,CRYM,CTNND2,BRINP1,PARD6A,ST8SIA3,FAM13A,EBI3,MBNL2,ERBB2,EYA1,FCGRT,FGFR1,PRELID3A,ZNF44,GLRB,GNG4,GPM6B,GRIK1,SPACA9,GSN,ADAM22,MSR1,ZNF862,NPR2,PDE4D,PENK,PLEC,CEP41,MAPK7,RAB3IL1,SEC61A2,MYH14,KLHDC8A,ZFP30,ST6GAL1,BCAN,SLC1A3,SLN,PALLD,ARHGAP26,DBNDD2,RAP1GAP2,SZT2" Drug 4351_DN Quinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "RALGAPA1,ASIC1,ACTN2,ADRA1D,AK2,CDC42BPA,APBA2,ARRB1,NCOA1,ATM,MTMR3,GYG2,CA4,HAP1,CRLF1,STOML1,WHRN,RIMS3,DAPK3,MFAP3L,DMPK,DTNA,HIPK3,EGFR,EIF4G2,STX2,FECH,FOXG1,AGAP2,PDLIM5,OGA,HBS1L,RAB30,NR3C1,KIT,MDM4,CNOT4,SLC25A23,ELOVL2,CCDC40,CCDC25,TCP11L1,SMARCD3,TMCC1,WDTC1,ZHX3,STX1A,PLCB1,ARHGEF12,ZNF34,TMOD1,VGF,SPHK2,WNK1" Drug 6687_DN Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "PPFIA3,SHROOM2,CDK10,KIF1A,PTBP2,CAMK2G,KRIT1,AKAP7,IQCK,ARHGEF10,CNTNAP2,FBXL5,KLHL3,SGSM2,CHRDL1,DENND4A,ST3GAL6,TRMO,NBEA,ATP2C1,TXNL4A,GLRB,BACH2,SCIN,DIPK1A,TM6SF1,SCAMP5,MYO9A,NDP,PAK3,PIK3R1,PLCD1,GRAMD1C,PTPRN2,TMEM231,PID1,C1orf54,FAT4,MSANTD2,TRAPPC13,MAPK12,SUPT20H,ASAP3,FBXO11,ST6GAL1,SIRT2,LIMCH1,CAND2,UHRF1BP1L,MAPK8IP3,TMEM121,CABIN1,TPM2,ZKSCAN5" Drug 4472_UP Estropipate [7280-37-7]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,ADRA1D,AP2A2,AK2,MRTFA,AMPD3,APAF1,ATM,STX16,BMP7,CHRNB2,HOMER3,RCHY1,NCOR2,CSF1,DUSP9,ETV1,FGF12,ANKFY1,OGA,RUNDC3A,ZNF276,GPM6B,MAN1B1,ITGA7,JAK2,SMAD1,KITLG,ADAM22,NPR2,EPN1,TNPO2,POU6F1,MINDY2,MAPK8,ELOVL2,PTPRH,PTPRN2,KCTD17,MYH14,FBXW7,KIF13A,KDM4B,DOK5,ARHGAP26,IQSEC2,VAMP1,COBL,TRIM2,TNS1,ZMYND8,ZKSCAN5,VAV2,BEST1" Drug 3248_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,ABHD6,NME5,AK2,SEMA6A,PPFIA3,ASPH,ATP6V0A1,CAMK2G,RCBTB2,DNAJB5,PICK1,CNTFR,NCOR2,SPOCK2,RUSC2,G3BP2,TMCC2,FCF1,CNNM1,OLIG2,VPS13B,DMTN,F3,FAM198B,FGF12,ALDH1L1,RND1,STON1,GRIK5,GRM3,BTN2A1,KCNN2,LIG4,VWA5A,SMAD1,ZNF862,PDE3B,PFKFB2,PLCD1,SLC25A23,TRIM68,SLC9A5,LIMCH1,TROVE2,ELOVL4,EXOC7,WSCD1,CHST8,ZNF34,HEY2,UPF3A,GDPD5,MVB12B" Drug 2286_DN Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "LTBP4,DOC2A,PPP4R4,ARRB1,CLGN,B4GALT6,BAG4,HP1BP3,ATN1,DTNA,DUSP9,DMTN,ZNF589,SORBS1,HBS1L,SRCAP,GLYR1,POLL,EML4,SPACA9,ITPKB,KHK,LSS,MAP4,KITLG,ADAM22,ZNF862,NPR2,OGG1,CDK18,PLEC,MAPK8,RAB3IL1,KCTD17,KLHDC8A,TCP11L1,SBF1,SH3BP2,PPP4R3A,KIF13A,EMC1,TROVE2,VAMP1,ARC,NSD1,PCDHA6,TMOD1,TRIO,MICAL1,NSD2,ZNF24,DNALI1,EPM2A,JPH3" Drug 6369_UP CGX 0596987; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DOC2A,BIN1,PKP4,GAS7,ADGRB2,NRP2,BMP7,CBFA2T2,KIAA1549L,AKAP5,CSF1,CHD5,EDRF1,CTIF,ZNF804A,MFAP3L,C2CD2L,KIAA0319,DTNA,DTNB,EDNRA,KCNMB2,EFCAB2,CSPG5,PNMA2,FYB1,DENND2A,ADAM28,GNAL,HSD17B1,ITIH2,KCND1,KIF2A,CD200,ADAM22,ZNF862,NCAM2,LRRN3,CEP41,PTAFR,PTCH1,PTPRB,PTPRH,BEND5,RNASE1,KDM4B,SPTAN1,SYT1,DOCK9,TPM2,TRPC1,VGF,VLDLR,PARP6" Drug 1496_UP Minoxidil [38304-91-5]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SYN3,ALCAM,MRTFA,APOC1,BCAS1,CADM3,ATP6V0A1,CFLAR,ST3GAL5,CA12,FADS2,CNTFR,FAM169A,PHF14,RASSF2,MFAP3L,LYPD1,TMCC2,TRAPPC9,ZNF589,FGF12,BAIAP2,FOXG1,AHDC1,RAB30,GRIK5,HSD17B1,TJAP1,INPP5B,KCNN1,MAP4,MBD1,TM6SF1,MMP16,ZNF862,NF1,RETREG1,ATG16L1,TSNAXIP1,SPP1,ZC3H13,STX1A,ACSBG1,SYT5,POPDC3,CRTC1,TEX15,HEY2,SEZ6L,TRIO,RUNDC3B,MICAL1,ZNF45,SPHK2" Drug 4690_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "RALGAPA1,AP2A2,TRMT9B,GAS7,PPP4R4,ATM,ALDH7A1,CFLAR,CAMK2G,QKI,HOMER3,ATRNL1,GREB1,TRAPPC9,IRAK4,EN2,SPEG,RRAGB,DLC1,FGF13,CAMSAP1,OGA,GAD1,GALC,GSN,HPCA,ICA1,ITIH2,KCNJ3,KCNMA1,MID1,ADAM22,NF1,CNOT4,PDE3B,MAPK10,RGS12,ROM1,ZNF821,FBXO11,SYBU,SMTN,DOK5,TROVE2,PHLDB1,WSCD1,ZMYND8,CLIP2,LAT2,ZIC3,SCG2,PARP11,ADAMTSL3,SSPN" Drug 6148_UP 2-Chloropyrazine [14508-49-7]; Up 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,AP2A2,BCAR3,BIN1,EPB41L5,PROM1,BMP7,BAIAP3,CFAP410,RUNX1T1,ABCG2,CABP1,DGKG,SPOCK2,KLHL3,TRAPPC9,ATN1,EDIL3,OPTN,MBNL2,ING4,ELAVL3,SRPK3,CEND1,FGFR1,GPR153,HPGDS,PCSK1N,KCNMB4,GPM6B,LILRA2,RAPGEF1,ADAMTS13,GRIN1,KIF3A,PTGDR2,KCNB1,KCNJ4,MARK1,NF1,OPCML,TNPO2,CEP41,PSMD13,KCNIP1,SELL,PKNOX2,FAIM2,PHLDB1,DMXL2,TPM1,TPM3,SLC17A7,PAK5" Drug 2756_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NME5,KIAA1324,AK2,SPARCL1,APBA2,ATM,ST3GAL5,CHI3L2,AKAP5,CREM,SH2B1,DCAF4,RIMS3,DBT,DCT,MAGI2,EFNA3,TNK2,HSD17B14,DLC1,FER,DPYSL4,GCNT2,GFER,GNG3,GPD2,TDRKH,GPR22,ELOVL5,ITPKB,KHK,NDUFA5,NEUROD1,PPP5C,MAPK10,ZDHHC14,SLC1A2,FAM214B,SLC11A1,ZBTB43,CAMTA2,ST5,TTBK2,PSD3,ARHGEF12,TGFBR3,THBS4,TK2,UCHL1,LAT2,ZNF23,ZNF45,SLC30A3,EMSY" Drug 3769_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "MTUS1,ALK,AMPD3,APBB2,APC,FAM131A,SLC4A4,ADGRB2,ARHGEF1,ZFYVE9,DNAJB5,CRMP1,DZIP3,DCAF4,RIMS3,SMG7,DLG3,EXOG,IRAK4,FOXG1,DCTN2,CGREF1,DISC1,IL12A,VWA5A,NF1,NFIX,CNOT4,PDE1C,STRN3,POLG,PRPH,FAM120C,ACSS3,C1orf54,SUSD4,ATXN7,ASAP3,SLC4A3,ZHX3,ARHGAP26,IQSEC2,ATP10B,SS18,SYN2,KIAA1107,ZEB1,SSBP2,HIRA,VLDLR,XRCC4,SNX27,DPF3,RNF146" Drug 2760_UP Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,NDRG2,ALCAM,BIN1,PPFIA3,RGS20,ASCL1,ATP2A2,CACNA1I,CFAP410,KALRN,SEPT7,CDH10,ARHGAP33,TAOK2,FADS2,HOMER3,MAGI2,C1orf61,CAMKK2,GAB1,GAD2,GCNT2,HNMT,VWA5A,MAP4,MMP17,BCO1,NRGN,CDK18,PDE3B,PACSIN1,PPP5C,PTAFR,ELOVL2,CCDC40,C1orf54,RPS6KA2,RASA3,FRMPD1,RPH3A,EPN2,PKNOX2,PEG10,ARC,ATP11A,CRTC1,HEY1,PARD3,HIRA,VIPR2,XRCC4,SYNC,HPS4" Drug 5885_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "CASK,SLC4A4,EIF4G3,ARHGEF7,CNOT8,KIAA1549L,CLU,CSF1,APPL1,DCAF8,RABGAP1L,EFNA3,RBM12,IRAK4,ING4,STX2,ETV1,ANKMY1,CGREF1,FYN,GAD1,GLRB,HNMT,SHISAL1,KIF2A,MEIS1,TAGLN3,NFYA,ODF2,PIK3R1,RAB3A,PID1,RAP1GAP,ROGDI,REV3L,SEC61A2,RXRA,SUPT20H,AMBRA1,FNDC3A,WDR37,SHANK2,MAPK8IP3,STX1A,FAM168A,SUPT5H,EXOC7,IQCE,TCF7L2,AMACR,HIRA,CADM1,ZNF32,MAP3K12" Drug 3880_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG2,PLA2G6,APBB2,GAS7,CDK13,CACNB2,CBFA2T2,B4GALT6,WHRN,NECTIN3,DAPK3,CTIF,ZNF804A,DSCAM,EFNB3,PLXNC1,HSD17B14,EZH1,F3,SCARA3,GCNT2,C1QL1,TXNL4A,GSN,ATXN2L,IL6ST,KCNH2,LMO2,MAOB,MAP2,MAP4,MIA2,MMP17,NF1,CNOT4,NPPA,NRGN,PRPH,PTHLH,FAM120C,ZSCAN2,CEP97,DOCK10,SLC15A2,ZCCHC24,STX1A,ATP11A,TNS2,THRA,BHLHB9,FAM155A,ZIC3,SYNC,SENP7" Drug 3441_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADRA1D,AP2A2,ALCAM,CDC42BPA,MARK4,EIF4G3,ST3GAL5,SCARB1,CRLF1,ZFYVE9,VAX2,QKI,HINFP,PDE4DIP,GPRASP1,FBXL5,SMG7,DNM1,EFNA3,CDKL3,SCML2,KAT8,SEMA4D,EFCAB2,B4GALNT1,GRB10,ARHGAP19,DHX35,IGSF1,INPP5B,ITPKB,KCNF1,TM6SF1,NF1,PRPH,APTX,PEX5,ZSCAN2,ATG16L1,FOXRED2,ZNF821,EPN2,SOX3,EMC1,CAMTA2,POGZ,ATP11A,TNS2,ATP13A2,TIAM1,CABIN1,HIRA,MAP3K12,GDPD5" Drug 4609_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AK2,ALK,CDC42BPA,GAS7,ASCL1,ASPH,CCDC181,N4BP2L1,KSR1,CFAP410,CACNB4,GPR37L1,TPP1,PDE4DIP,MYEF2,DRP2,CNNM1,PLXNC1,EN2,ATP8A1,FYB1,GABRA3,ADAMTS8,GRM8,GUCY1A2,HTR2A,KCNA2,KCNC1,KCNJ5,PACRG,MBNL1,MYH3,MYO7A,PCSK5,PDE4B,PDE4D,PIK3R1,STRN3,NEK11,MRAS,RASA3,ARHGEF40,SNCA,SOX10,ARC,SYT5,TACR1,DOCK9,TNS1,TRIO,UBE3A,WIPF1,SLC17A7,EPM2A" Drug 7220_UP Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "MARK4,ASPH,SLC4A4,ADGRB1,SCAPER,BTRC,CHM,ZFYVE9,PLAA,SULT4A1,SNPH,GIT2,EGR3,HSD17B14,ERBB2,KIAA1109,FGFR3,OGA,FYB1,RUNDC3A,GRM1,KLF12,ELOVL5,VWA5A,MSI1,ZNF862,NEUROD1,NF1,OLR1,ENPP2,NLE1,MAPK8,WDR25,PTHLH,ZSCAN2,ZDHHC14,KCNIP1,RYR1,MRAS,FRMPD1,SYBU,SLC6A9,BTBD7,ZCCHC24,ATP10B,MAPK8IP3,VAMP1,WSCD1,TRIM2,TK2,TPM1,AMACR,FAM155A,UBE3A" Drug 2538_DN Sulfapyridine [144-83-2]; Down 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG3,CDK10,CDK13,SLC4A4,ADAM23,ADAM15,C5,OSGIN2,CAMK2G,NFS1,KYAT1,FOXN3,HOMER3,BAG4,CPS1,SH2B1,VCAN,DAPK3,RUSC2,CDON,F8,ZNF589,GAA,ZNF44,INPP5K,ACOT7,ICA1,ITPKB,MAP4,NF1,NFYA,NUMA1,PIK3CD,PIK3R1,NLE1,ZDHHC14,GTDC1,GSTCD,LGR4,TRAPPC13,GALNT10,PPP4R3A,BTBD7,SLC20A2,WDTC1,ZBTB43,SS18,SZT2,THRA,KCTD2,KAT6B,FLRT2,NSD2,EPM2A" Drug 4292_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,SPARCL1,PKP4,ZSCAN18,SLC4A4,NRP2,BMPR1B,BAIAP3,NEURL1,TAOK2,EPS15L1,RAB28,FAM189A2,VCAN,NTM,SHANK1,DTNA,HIPK3,REEP2,FGF1,PDLIM5,TBR1,ZNF44,GPR17,GPR22,GPER1,GRIK5,GRIN1,CACFD1,IL6ST,AFF1,CNOT4,PIK3R1,EPN1,PPARA,ELOVL2,ZCWPW1,RET,RGS4,RAVER2,SELL,DZIP1,SHANK2,HECW1,KDM4C,MCF2L2,ACSBG1,CRTC1,TPM3,AMOT,VSNL1,LAT2,SLC13A3,SLC17A7" Drug 5611_UP Cotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,BRINP2,ADGRB1,USP2,CDO1,CHRNA4,TAOK2,CLCN4,CNR1,AKAP5,CSF1,MICAL2,SNPH,DGKG,SPOCK2,DMPK,FUT9,GAP43,SIGLEC8,ATP8A2,POLL,GRIN1,GRM1,SOX21,IRAK3,KCNJ5,LMO2,AFDN,MYO7A,NPY,NTRK3,CDK14,PMP2,C19orf57,MAPK8,WDR25,CNTLN,ENOX1,ZMAT4,KLHL11,MYH14,TMEM206,FRMPD1,KANSL3,SLN,MAPKBP1,KIF13A,CDK19,SYT11,SYT5,PIK3R5,FLRT2,XRCC4,SPHK2" Drug 6476_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACHE,NDRG2,ADORA1,SLC4A4,ATP2B2,NRP2,CFLAR,SCAPER,SGCE,LDLRAD4,HAP1,NEURL1,CHN2,KIAA1549L,SULT4A1,AATK,CHD5,VCAN,CTIF,SV2A,RASL12,FAM198B,CORO2B,CAMKK2,GRM7,VSIG4,ICA1,JAK2,KCNH2,MDM4,MEF2C,ADAM22,MYCN,MINDY2,ZSCAN2,GSTCD,TCP11L1,KCNIP1,PPP1R9A,PPP4R3A,COA1,ATP10B,SS18,PLCB1,SYT5,ROBO3,DICER1,TGFBR3,TRO,TRPC1,TRPC3,WIPF1,NSD2,SLC30A3" Drug 2637_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SYN3,AGT,ALCAM,BIN1,CDC14B,MARK4,ATP6V0A1,CDK5R1,GYG2,HAP1,CHRNB2,TAOK2,RAB28,TMEM59L,WHRN,SLC4A7,ABI3BP,CRY2,VCAN,CTH,RIMS2,RUSC2,C2CD2L,TMCC2,MBNL2,HSD17B14,APC2,GPR153,GAD2,GCNT2,INPP5B,NOVA2,PENK,RETREG1,PACSIN1,PROX1,RGS10,SYNDIG1,SCN8A,FNDC3A,SLA,WDTC1,KIF21B,SOX10,KDM4C,ERC1,SPTAN1,SPTB,KIAA1107,OBSL1,CHST8,RBFOX2,ZNF45,FAM13C" Drug 4577_DN Prednisone [53-03-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "PLA2G6,MRTFA,EPB41L5,ARHGDIG,ADGRB2,BAIAP3,CBFA2T2,TPP1,DNAJB5,NRG2,PDE4DIP,RUSC2,KLHL3,CHRDL1,CDON,ATN1,FEM1B,EFNA3,EGFR,PLXNC1,DMTN,STX2,F3,FGF13,C1orf61,USP19,GLRB,TDRKH,GRK4,ELOVL5,KCNJ4,MAPT,PPP5C,PROX1,PTN,TCP11L1,IL17RB,FNDC3A,BCAN,SLC1A7,ZHX3,NXT2,MCF2L,KIAA1107,CRTC1,THRA,TIMP4,AMACR,VGF,VIPR2,WIPF1,XRCC4,KCNAB1,TIGD6" Drug 1538_DN Danazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG2,SLC4A4,ATP2B1,SCAPER,BTRC,CAMK2G,CBFA2T2,SULT4A1,CREM,EDRF1,DAPK3,GIT2,NR1D2,FCF1,EGFR,DENND4A,F3,ACSL4,SCML2,PRELID3A,CSPG5,GLYR1,CNTRL,GRB10,RNFT2,MITF,NFYA,SLC11A2,PDE3B,MAPK8,WDR25,TMEM231,RGS10,ARHGEF10L,NEK11,SEC14L1,ZNF821,SH3BP2,ANKRD6,PPP4R3A,MAPKBP1,ZCCHC24,NCDN,ELOVL4,CEP68,ARC,ASTN2,KAZN,IQCE,FBXW11,TMOD1,VGF,SPHK2,UBE3B" Drug 6778_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AMPD3,BIN1,SEMA7A,APC,ST3GAL5,CACNB2,CACNG1,KYAT1,SLC16A4,NEURL1,ZFYVE9,HAPLN1,GREB1,JAKMIP2,ZNF804A,TRAPPC9,USH1C,C3orf18,ENO2,ST3GAL6,PDLIM5,TMEM8B,INPP5K,GLYR1,TDRKH,LPAR4,GRM1,GRM7,KCND3,MID1,TAGLN3,ZNF862,NTRK3,PLP1,LRP12,MAPK8,RAB3IL1,SLN,KDM4C,MAPK8IP3,STX1A,ABCC8,PLCB1,DOCK9,PSD3,TGFBR3,TTPA,ZNF711,ZNF24,CA10,SEMA3B,KCNAB1,ITM2C,MVB12B" Drug 3390_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADCY2,AP2A2,PLA2G6,CDC42BPA,N4BP2L1,AZGP1,BAIAP3,CHRNB2,TAOK2,RAB33A,AKAP6,COL9A3,TENM4,ARHGEF10,KLHL3,TNK2,MRNIP,FABP7,TUBB4A,KIAA1109,FYN,GCK,ADAM28,GFER,C1QL1,GNG4,GRK4,KCNJ5,MDFI,MOBP,TAGLN3,NF1,OMG,EPN1,MASP1,PTAFR,PTPRD,C1orf54,ZMAT4,PNMA8A,SALL1,ST6GAL1,BCAN,RPH3A,SLCO1A2,OGDHL,TSNAXIP1,UNC5B,ARHGAP26,SMG6,THRA,LAT2,SLC17A7,MVB12B" Drug 6178_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AMPH,SLC4A4,MPDZ,HIP1R,TCEAL2,ABCG1,SIPA1L1,PDE4DIP,SNPH,SPOCK2,ECM2,SEZ6L2,EFNA3,MBNL2,ELAVL3,TNK2,MRNIP,DMTN,CAP2,GPR153,TMEM8B,SIGLEC8,GLRB,SPACA9,HTR2A,KCNB1,KIT,SAMD14,MYO7A,NF1,PAX6,PDE4B,MBOAT7,VPS13C,PTPRN2,HSPA4L,SH3BP2,FERMT1,SLC1A7,SLC11A1,SLCO1A2,KDM4B,ATP10B,SS18,TCF4,TMEM151B,PSD3,DICER1,SEZ6L,LMF1,ZBTB38,SLC17A7,GJC2,DPF3" Drug 7343_UP Moxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADORA1,ADORA2A,NME5,PLA2G6,BIN1,ARRB1,RASL11B,BACH1,BTRC,CFAP410,CAMK2G,CD86,CLGN,QKI,WHRN,CRY2,FAM169A,RIMS3,INTS1,DAPK3,GIT2,ZNF804A,DSCAM,DTNA,CNNM1,EFNA3,ING4,VPS13B,IGSF6,F8,OLFM1,FGFR1,PRELID3A,ALDH1L1,CNTRL,SPACA9,GRIK5,ATXN2L,IL6ST,MIA2,NF1,EPN1,PTCH1,RIPOR1,FAM184A,RPS6KA2,ABLIM3,ARC,ANKRD12,TEX15,FLRT2,KLC2,HPS4,SSPN" Drug 1412_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; HL60; HG-U133A" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,ADAR,C1QTNF1,C1QTNF3,APOC1,ARNTL,CAPRIN2,CACNA1I,CAST,CBFA2T2,LRBA,FOXN3,RAB28,FAM189A2,TMEM184B,BAG4,DAPK3,SGK2,SORBS3,CD320,ANKFY1,GAA,PADI2,MAN1B1,ITIH2,ST8SIA5,SMIM7,PLTP,POLG,PTAFR,PTH1R,PTN,RALGDS,CRTAC1,TCP11L1,ZNF821,ELMO2,SLC20A2,INTS9,MAPKBP1,KDM4B,UNC5B,KIF1B,LMO3,NCDN,TCF4,TCF7L2,CRTC1,CHST5,VGF,XRCC4,PRDM2,ADAMTS9,CAMK1G" Drug 6383_UP Orlistat; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,ACTN2,LTBP4,AMPD3,APBB2,RASL11B,CCKBR,CDH10,COL9A3,IFFO1,RIMS2,SPOCK2,MFAP3L,TRAPPC9,DTNB,ECM2,EFNA3,ELAVL2,F5,DCTN2,RASL10A,FUT9,GAB1,SRCAP,MALT1,GLYR1,GLS,GNG4,GRM1,ICA1,C2orf72,IL6ST,ITGA7,NEUROD1,PCDH9,PDE4A,PLEC,PTN,PTPRO,ATG16L1,CNKSR2,RPH3A,SLC2A5,PKNOX2,WDTC1,NMNAT2,PEG10,TROVE2,AJAP1,POPDC3,ATP11A,DOCK9,TF,TLR4" Drug 4830_UP Piperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SYN3,ACTN2,NME5,ANK1,APC,CDC14B,CDK13,RGS9,LDLRAD4,ARHGEF1,SULT4A1,ARHGEF6,AKAP7,GREB1,SNPH,CTIF,ATN1,PLXNC1,EIF4G2,EN2,RASGRP2,NRN1,ATP8A1,CAMSAP1,C1orf61,HBS1L,DISC1,GPM6A,PCLO,NR3C1,ATXN2L,LAMA2,MAOB,MSR1,MYH7,NCAM1,PDE1C,ENPP2,PIK3CD,PLTP,MRAS,CCDC88A,HECW1,ZC3H13,SYT11,JMJD6,POPDC3,WSCD1,DMXL2,PCDHGA10,WNK1,KCNAB1,FAM13C,DPF3" Drug 4196_UP Benperidol [2062-84-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP2A2,NRP2,HAP1,CAMK2A,LDB2,ARHGEF2,SEPT7,MAGI1,JAM2,AKAP5,ABCG1,RGS6,SUSD5,DBT,ING4,DISC1,GNG3,GPM6A,GPR17,GSTM5,VWA5A,ADAM11,P2RY13,NF1,SMOX,PTN,PTPRG,ACSS3,C1orf54,GAL3ST4,RFX2,ROM1,RPS20,KCNIP1,NTNG1,DZIP1,PREX2,PKNOX2,OGDHL,DOP1A,TNIK,ZHX3,THSD1,MAPK8IP3,ACSBG1,FBXW11,TK2,RPRM,ZNF154,WNK1,PARP6,SLC17A7,KCNAB1,EPM2A" Drug 5598_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SEMA6A,AMPD3,AMPH,APC,BACH1,GYG2,CA4,CBFA2T2,AKAP5,CSF1R,SNPH,KIAA0513,RASSF2,PHYHIP,DAPK1,CTIF,DMPK,DRD1,EFNB3,ELAVL3,ZNF44,ERAP1,SIGLEC8,GLYR1,STON1,GPR37,GRIN1,AP4S1,SCRG1,AFDN,MMP16,ADAM22,NPPA,SNTG1,PCDH9,PDE1C,SERPINI1,LRP12,POU3F2,MAPK7,FAT4,KCTD17,FAM214B,RIMS1,KDM4B,TSNAXIP1,IZUMO4,RGL1,TCF7L2,TRO,TRPC3,TRPM2,FAM155A,SLC17A7" Drug 4681_DN "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NME5,ATP1A3,SLC4A4,STX16,FUBP1,LDLRAD4,CLTB,ABCG2,TCEAL2,CREM,SH2B1,AATK,CTIF,MFAP3L,SMG7,CHRDL1,EDNRA,FEM1B,TENM1,COQ7,ZNF549,CDKL3,ANKMY1,CORO2B,SORBS1,PNMA2,FYB1,GABRA2,GNG3,ICA1,IGFBP1,MMP16,NDP,NEUROD1,NF1,NNAT,OPCML,STRN3,CNNM2,RALGDS,FAM184A,FRMPD1,SIRT2,ZKSCAN3,SNCA,DOP1A,SOX15,IZUMO4,INKA2,SYT11,ASTN2,THRA,OSBP2,VIPR2" Drug 3884_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,ADCY2,SYT13,BEGAIN,BIN1,APAF1,CDK10,NUMB,ATP2B3,NRP2,MTMR3,CACNA1I,HAP1,RUNX1T1,RCBTB2,RIPOR2,DCT,RABGAP1L,ECM2,FGFR1,KHDRBS3,GRM1,GSTM5,SOX21,C2orf72,LAMA2,LSS,MAPT,MID1,MOBP,MSR1,TAGLN3,NAP1L1,SLCO1C1,PDE4A,PLCD1,PDZRN4,STRN3,CEP41,MARCH1,C1orf54,ENOX1,TTLL7,CARF,LIMS2,SLN,ATP10B,TBCEL,DMXL2,TMOD1,TRPM2,UCHL1,XRCC4,JPH3" Drug 6610_UP Carisoprodol [78-44-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "KIDINS220,DDO,APOC1,RASL11B,ADAM23,BACH1,SCAPER,BAIAP3,CACNB4,CAMK2B,FAM149A,ENTPD4,DCC,MFAP3L,CHRDL1,DMD,EDIL3,EDNRB,APC2,REEP2,FGF1,FOXG1,HBS1L,GCNT2,RND1,GRM8,SOX21,ICA1,KHK,MAG,MBNL1,MGAT3,AFDN,MOBP,ADAM22,NEFM,NOVA1,KCNK10,NLE1,PPP1R1A,MAPK10,MARCH1,KCTD17,SCN2A,FRMPD1,ASAP3,SPTAN1,PHLDB1,CHST5,AMACR,ZNF24,STMN4,SCG2,DPF3" Drug 1868_DN Dapsone [80-08-0]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ABR,BRAP,ARRB1,MARK4,SYNJ2,SLC25A14,SOCS6,TPP1,CLOCK,OSBPL3,DZIP3,ZNF337,EEF1A2,EPB41L2,VPS26C,FECH,HBS1L,ERAP1,MAP4,ZNF862,NINJ2,SLC11A2,SETD4,GPR85,MINDY2,SNRK,TMEM231,ATG16L1,UEVLD,ZC3H14,HSPA4L,FBXO11,URGCP,ZCCHC24,SPTAN1,CDK19,ZBTB43,MAPK8IP3,KANK1,STXBP1,TCF4,ARHGEF12,TGFBR3,TK2,TNNT1,ZMYND8,ZKSCAN5,CADM1,UPF3A,GDPD5,LMAN2L,WIPF2,UBE3B,ACTR3B" Drug 4701_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG2,NME5,EPB41L5,SEMA4G,ARNTL,ARRB1,SLC4A4,CFAP410,CACNG1,QKI,AKAP6,CSF1,CNTNAP2,SPOCK2,GIT2,DTNA,HIPK3,ING4,ELAVL3,FGFR3,CAMSAP1,AGAP2,ANKFY1,GRB10,KCNH2,KITLG,MSI1,PDE3B,PENK,PACSIN1,C19orf57,LRRN3,PPP5C,ELOVL2,RGS12,NUDT11,ROM1,SYNDIG1,KCNIP1,SLC9A5,DOP1A,CLSTN2,PHLDB1,SYT11,TCF7L2,PCDHA6,CHST5,FLRT2,VGF,ZIC3,WNK1,PRDM2,KCNAB1,UBE3B" Drug 4175_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "CNTNAP1,GAS7,SEMA4G,MARK4,ALDH4A1,ALDH7A1,LDLRAD4,CFAP410,PTBP2,SLC16A4,WHRN,NOS1AP,SPOCK2,TMCC2,EXOG,IRAK4,ELN,EZH1,FHL1,AFF2,GPR153,GAD2,DISC1,SEPT9,GNG4,ICA1,TJAP1,ITIH2,KCNN1,MAPT,ADAM22,MX1,MYT1,PDE1C,PRKAR1B,WDR25,RAB3IL1,C1orf54,SH3GL3,SMTN,SNAP25,CLSTN2,THSD1,MAPK8IP3,VPS13A,PLCB1,ARC,POPDC3,MCF2L,TBCEL,HEY2,TPM2,MICAL1,EPM2A" Drug 3045_DN Hymecromone [90-33-5]; Down 200; 22.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,MRTFA,AMPH,BIN1,APBB2,MARK4,ATP2B2,NRP2,HIP1R,CLGN,EPS15L1,PLAA,CLCN4,NCOR2,CTNND1,B3GAT3,SORBS3,F5,FHL1,EFCAB2,KHDRBS3,GABRA4,INPP5K,AHDC1,LILRA2,AP4S1,SLC2A6,ATXN2L,ELOVL5,HPCA,TJAP1,KCNJ5,MAP4,NCAM1,NOS1,PDE4D,RETREG1,MTRF1L,PROX1,PTCH1,ZSCAN32,NEK11,ZNF821,SCG5,FAM102A,SNCA,ZNF415,TSPYL2,IQCE,TCF7L2,PCDHGA10,TEX15,TPM2,SSPN" Drug 2356_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "AP1B1,PPFIA1,APC,APP,CDK10,BCL7A,CFLAR,SCAPER,CAST,LRRFIP1,CLCN3,IQCK,BAG4,CLOCK,OSBPL3,CYBB,SGSM2,ANKMY1,F3,ZNF589,FGFR1,CRCP,LILRB4,GPR22,CACFD1,ITGAM,ITGAV,MIA2,NFYA,SLC11A2,PIK3R1,RETREG1,MAPKAP1,PPP2R5C,TMEM104,C1orf54,BSDC1,RGS10,CCDC25,CLIP1,PEX26,MAPK8IP3,SEPT8,KANK1,SYT11,EXOC7,TBL1X,TLR4,PARD3,KAT6B,RBFOX2,NR2C2,XRCC4,WIPF2" Drug 7495_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,CNTNAP1,APBB2,APOC1,CDK10,ARRB2,SLC4A4,EIF4G3,ST3GAL5,CFAP410,CAMK2B,CBFA2T2,CHRNB2,CLU,RAB26,PPP6R2,DMPK,TRAPPC9,DYNC1I1,APH1A,AASS,PLEKHO1,COQ7,DMTN,CDKL3,TUBB4A,EFEMP1,ZNF589,TRMO,CINP,FYN,DENND2A,SRCAP,POLL,KLF12,SCIN,LIFR,KCTD15,PRPH,TMEM231,SBF1,FAM214B,PDZD2,TCF4,HIF3A,LMF1,TRIM9,MAP3K12,EMSY,EVI5,PARP6,PLSCR4,ST7,DPF3" Drug 1851_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ABHD6,MRTFA,CDC42BPA,PPFIA4,APC,APOC1,KIF1A,ADAM23,CDK5R1,MTMR3,INA,CDC27,PLAA,AKAP7,IQCK,NRG2,CSF1,GSDME,ST8SIA3,SIDT2,PLXNC1,MRNIP,EPB41L2,RRAGB,AFF2,DCTN2,SRCAP,GPD2,SPACA9,ADAMTS8,NF1,PENK,PLCD1,PMP22,PTPRN2,PEX5,RGS10,MYH14,MAP6D1,RPS20,RASA3,SH3BGR,RAB3GAP1,TMCC1,DOP1A,DBNDD2,TSPYL2,CEP68,STX1A,DNMBP,SLC44A1,PARD3,WNK1,PHTF2" Drug 3728_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ARID1A,PLA2G6,C1QTNF3,ALAD,AMT,APBB2,ATP2A2,CAMK2B,CAST,FOXN3,CHRNB2,TAOK2,RAB26,CSNK1E,ARMCX2,HIPK3,IRAK4,ELAVL3,ANKMY1,FGF1,PNMA2,POLL,GPM6A,GRIK2,ELOVL5,ICA1,VWA5A,MAP2,MAPT,MOBP,TAGLN3,NPR2,PDE4A,GPR85,PFKFB2,PPP5C,PRKAR1B,PTCH1,GAL3ST4,ASAP3,SLC9A5,TSNAXIP1,IZUMO4,COLGALT2,CEP68,MLC1,CHST8,R3HDM1,RPRM,ZNF24,TFIP11,MAP3K12,NT5M,TIGD6" Drug 2929_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "PLA2G6,BIN1,APBB2,APOC1,ARHGDIG,CACNA1I,CA12,CACNB4,REPS2,GPR37L1,ASIC3,COL9A2,CTNND1,SPOCK2,EFNA3,EGFR,SORBS3,DLC1,BAIAP2,DCTN2,GAD2,ATP8A2,FERMT2,ITPKA,MAP4,NINJ2,NNAT,NPR2,NPTX2,CLDN11,PPARA,ELOVL2,KCTD17,FOXRED2,RASA3,CCDC92,RPH3A,EPN2,SHANK2,SLN,MAPKBP1,ZHX3,ZC3H13,RAP1GAP2,SYN2,ADGRL3,TBCEL,PCDHA3,TJP1,VIPR2,KCNK12,SLC17A7,PCBP4,TIGD6" Drug 5972_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ACTN2,TRMT9B,APBA2,GAS7,PPFIA3,CADM3,CFAP410,CBFA2T2,CDC42,ARHGEF6,BAG4,NCOR2,ELAVL2,ELAVL3,RASGRP2,FABP7,CACNG3,DLC1,GAB1,TRAF3IP2,ALDH1L1,GFAP,GRM1,PTGDR2,IFI16,KCND3,KHK,MMP17,NEK1,NF1,NOVA1,PCBP3,PFKFB2,POU3F2,TMEM104,PEX5,RAB3A,ASIC4,BCAN,KDM4B,WDTC1,EMC1,ZNF423,MAPK8IP3,EXOC7,TRIM2,ARHGEF12,CRTC1,PCDHA5,PARD3,PRMT8,VGF,LAMP5,ITM2C" Drug 3620_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,ALCAM,AMT,APP,CADM3,GYG2,BAIAP3,LDLRAD4,CACNA1A,CDH10,NECTIN3,PDE4DIP,PPP6R2,ATN1,EDNRA,SIDT2,EFNB3,PLXNC1,PLEKHO1,STX2,CEND1,FGF12,FGFR1,FOXF2,OGA,GCNT2,SRCAP,GPER1,SPACA9,ATXN2L,ADAM22,BCO1,NPTX2,MINDY2,PPP5C,PRKCB,RELN,GON4L,TMEM104,PTN,ZSCAN2,ZNF821,SLC2A5,DOK5,EMC1,SPTB,ATP11A,KIAA1107,PCDHA5,DNAH7,TNS1,PIK3R5,TRPC1,ZKSCAN5" Drug 3610_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ABHD6,NDRG2,ALCAM,GAS7,FAM131A,PPP4R4,ADAM15,CBFA2T2,CHM,SLIT2,FADS2,RCHY1,NCOR1,DAPK3,HIPK3,EFNA3,SORBS3,EPB41L2,ZNF589,KIAA1109,FGF13,ERAP1,TXNL4A,GLYR1,GPR19,SPACA9,GSN,MAP4K5,IL6ST,KCNMA1,KPNA5,MDM4,NUMA1,NLE1,EPN1,PLXNB1,PTHLH,RAB3A,RAD52,RIC8B,FAM214B,ZCCHC24,EMC1,IQSEC2,STX1A,ATP11A,KIAA1107,TCF7L2,RPGRIP1L,TGFBR3,TMOD1,MAP3K12,PCBP4,PHTF2" Drug 5414_DN "Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "OSBPL1A,ALCAM,PPFIA3,ALDH7A1,KIF1A,ADGRG1,SLIT2,AKAP7,CSNK1E,SIPA1L1,DAPK3,DBN1,SORBS3,MRNIP,EML1,ENO2,EPB41L1,EZH1,ZNF589,FGFR1,IQCG,OGA,RUNDC3A,GPER1,GRIK5,INPP1,MAPT,TM6SF1,MIA2,ZNF862,NF1,NUMA1,PLXNB1,RAB3A,RAD51D,RGS3,RGS10,RGS12,NEK11,RPS6KA2,KIF13A,WDTC1,EMC1,SPTAN1,VAMP1,VPS13A,SEMA4A,TCF7L2,SLC44A1,TK2,TPM1,ZNF45,TFIP11,GDPD5" Drug 7533_DN "11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADORA1,FAM135A,APOC1,MARK4,BRSK2,CCNT1,FOXN3,TAOK2,EDRF1,NOS1AP,CTIF,DCT,TRAPPC9,DTNA,USH1C,ELN,DMTN,DLC1,ZNF589,FLNC,DPYSL4,GLS,KCNMB4,GPER1,RNFT2,RASSF8,NXPH3,ATXN2L,KCNF1,KCNH2,NELL2,CNOT4,NPR2,PALM,PCDHGC3,PCDH9,RETREG1,MINDY2,PPP5C,PRPH,GDPD2,PTAFR,RAD52,RFX3,RGS10,KCTD17,SLC1A2,FAM214B,MAPK8IP3,SLC44A1,R3HDM1,TRO,FAM155A,REEP1" Drug 7325_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "NDRG3,EPB41L5,APOC1,DNAH17,KIF1A,SYNJ1,BTRC,CAMK2G,ARHGEF2,SOCS6,B4GALT6,NMT2,FADS2,EDRF1,ZFYVE16,TBC1D5,RIMS3,ATN1,GNE,ST8SIA3,OPTN,STX2,FAM49B,PRELID3A,MALT1,GPR75,GLS,GNAS,STON1,GPR22,CNTRL,ELOVL5,HNMT,MAP4,KITLG,MPP2,PDE3B,PKIA,RIPOR1,RASGRF1,KCTD17,ZFHX4,PAQR6,ZNF821,CXXC4,RBM34,PLCB1,RPGRIP1L,DICER1,ZNF34,RBFOX2,FAM155A,WIPF1,ZNF74" Drug 5850_UP Vidarabine [5536-17-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,APC,BLM,MYRF,BTRC,MAP7,MTMR7,LHX2,ABCG2,AKAP5,CREM,FEZ1,MFAP3L,C2CD2L,DMPK,DRD1,MBNL2,EIF4G2,RGS17,RASGRP2,ZNF549,CORO2B,OLFM1,TMEM164,SCARA3,SEPT9,GPD2,GRM7,HRH3,KCNF1,KCNMA1,ADAM22,FSD1,PRKAR1B,MAPK9,PTPRD,FAM184A,ZMAT4,RET,RGS4,RGS7,RGS12,FBXW7,ASAP3,SLC4A3,PKNOX2,SMARCD3,SOX10,BEX1,SAMSN1,CEP68,SSBP2,REEP1,MPPE1" Drug 631_UP benserazide hydrochloride; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "SPOP,CDC42BPA,CDC14B,ASPH,BCL7A,BMP7,SCARB1,NIPBL,CHD1L,FEZ2,CSNK1G3,KIAA0753,SH3GLB1,EPB41L2,FGFR1,ATP2C1,GNAL,RBPJ,IL6ST,MTR,NF1,NNAT,OPCML,PCMT1,PDE4D,PDPK1,PPP3CA,RAB3IL1,RAP1GDS1,ROGDI,PCMTD2,FERMT1,FUZ,SLC11A1,KBTBD4,SMARCC2,MAPKBP1,TMCC1,WDTC1,FNBP1,CAMTA2,ITPRID2,ST5,PRRC2C,MLST8,TRIM2,ARHGEF12,SPX,ZMAT3,SMUG1,TSC1,UBE3A,DNAJC12,HPS4" Drug 3332_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ARID1A,AK2,BCAR3,CDC42BPA,CDK10,BCL7A,CFLAR,CDK5R1,CAMK2G,SOCS6,PLEKHB1,RAB28,ZFYVE9,QKI,SLC4A8,ZNF337,ATN1,TOM1,SUGP2,PLEKHA1,GPR153,TXNL4A,PRRC2B,GRB10,NR3C1,BRINP3,INPP5B,ITPKB,KCNK1,MATK,ZNF862,NFYA,NUMA1,PRKAR1B,CNNM2,WBP1L,SIDT1,RAB5B,CEP97,CLIP1,SH3BP2,FERMT1,PPP4R3A,SPTAN1,POGZ,NCDN,SEMA4A,SLC44A1,BHLHB9,VAV1,XRCC4,ZBTB14,LRP8,FZD3" Drug 4145_UP Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "DPF1,NR0B1,APBA2,GAS7,PPP4R4,ADAM23,KSR1,MTMR3,CAMK2B,EPS15L1,CLCN4,CNR1,AKAP7,CSF1,ARHGEF10,VCAN,CNTNAP2,DAPK1,PARD6A,NTM,HS3ST2,HSD17B14,OGA,GAD2,GCNT2,GRIK5,GUCY1A2,IRAK3,HTR5A,KCNMA1,KHK,LAMA2,ADAM22,NCAM1,NELL2,SLCO1C1,NTRK3,PURG,POU3F2,ELOVL2,CCDC40,RGS4,RGS12,RYR1,WDTC1,DOK5,SP4,NMNAT2,PHLDB1,SYN2,TAC3,DOCK9,FLRT2,NT5M" Drug 3393_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC2,KIDINS220,PLA2G6,ALCAM,TRMT9B,AMPD3,ANK1,PRX,LDLRAD4,CA4,CAMK2G,RHBDL1,CCNT1,ARHGEF2,SNCAIP,ARHGEF10,CDON,ATN1,DTNA,LRRC23,ERBB2,ERCC2,NRN1,FHL1,EFCAB2,CAMKK2,FYB1,C2orf72,ITGA7,KIF5A,KITLG,ADAM22,MX1,PALM,PLP1,PTAFR,ZMAT4,MYH14,KLHDC8A,CARF,SH3GL3,RPH3A,ARC,SYN2,POPDC3,RPGRIP1L,CRTC1,TMOD1,UBE3A,CLIP2,LAT2,SCG2,PHTF2,NUP214" Drug 5390_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "MRTFA,AMPD3,GAS7,PLA2G4C,CHRD,CFLAR,KSR1,GYG2,BSN,NEURL1,CHN2,SULT4A1,AKAP7,COL9A3,TCEAL2,CYBB,SPOCK2,GSDME,TMCC2,COQ7,APC2,FGF12,CAMSAP1,FHL1,SRCAP,GLYR1,PCLO,GRM3,RASSF8,IL11RA,KCNJ5,VWA5A,MAOB,MAP2,ZNF862,NOVA1,PDE3B,PDE4B,PLCD1,LRP12,PTN,PTPRH,CCDC40,RGS4,MYH14,MRAS,SLA,SLC2A5,PKNOX2,SLN,SAMSN1,SZT2,CABIN1,MICAL1" Drug 5829_UP Ticarcillin sodium [4697-14-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ADORA1,MTUS1,PLA2G6,C1QTNF1,BIN1,AMT,CDC14B,CFLAR,MYRF,LHX2,DNAJB5,COL9A3,HAPLN1,CNTNAP2,RIMS3,GIT2,DBT,DPH1,SGK2,MRNIP,ELN,ETV1,BAIAP2,SORBS1,CHL1,ZMYND11,GCNT2,AHDC1,TDRKH,NR3C1,GSTM5,MAP4K5,IL11RA,NUMA1,PAK3,ENPP2,PPP5C,SH3TC2,FAT4,FAM184A,RET,CLIP1,ZNF821,AMBRA1,PEX26,SLC20A2,ZBTB43,SYT11,TAL1,CRTC1,PCDHA5,FLRT2,WIPF1,LAT2" Drug 1476_UP Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "RBM10,ADORA3,AK2,PLA2G6,C1QTNF3,LTBP4,MRTFA,CDC42BPA,ARHGDIG,SLC4A4,CFLAR,ST3GAL5,LDLRAD4,ARHGAP33,CRLF1,HOMER3,BAG4,CREM,CRMP1,RGS6,PPP6R2,MAML1,DMPK,SHANK1,TRMO,OGA,POLL,GNG3,GRB10,TJAP1,TM6SF1,TAGLN3,NF1,PCBP3,SETD4,PDE3B,PENK,PMP22,PRODH,RAD52,TRIM68,MYH14,KCNIP1,PEX26,SLC9A5,ZC3H13,ARC,EXOC7,CRTC1,HEY2,TMOD1,SLC30A3,KCNAB1,RNF170" Drug 2817_UP Gelsemine [509-15-9]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "MARK4,SLC4A4,ATP2A2,MYRF,INA,SEPT7,ARHGAP33,RCBTB2,AKAP7,RCHY1,NECTIN3,PDE4DIP,SDC3,TMCC2,EXOG,SGK2,FRY,EFNB3,SORBS3,PIPOX,FGFR3,SORBS1,B3GAT1,GFER,ELOVL5,TJAP1,KCNA1,KCNF1,AFDN,NDUFA5,NF1,PDE1C,ELOVL2,FAM120C,MYH14,TCP11L1,RPS6KA2,SYNDIG1,KCNIP1,SAFB,SFPQ,SH3BP2,DOCK10,NLGN1,RPH3A,PKNOX2,SLC9A5,CXXC4,KIF13A,EMC1,ATP10B,MAPK8IP3,SPHK2,ST7" Drug 4393_UP Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.23E-05 1.00E+00 3.13E-04 3.56E-03 54 198 "ASIC1,LTBP4,BEGAIN,SEMA4G,ASCL1,RASL11B,SLC4A4,BAIAP3,LDLRAD4,CFAP410,RUNX1T1,NEURL1,CDO1,GPR37L1,TPP1,VCAN,NOS1AP,CNIH3,SPOCK3,SRGAP3,EGR3,RASGRP2,TUBB4A,KIAA1109,HPCAL4,GRIK1,GRIK5,GRM1,GRM7,IRF8,KCNMA1,MYCN,NCAM1,NF1,KCNK10,PDE1C,EPN1,C19orf57,SAMD9,PTPRB,ENOX1,KCTD17,MRAS,SLC2A5,KANSL3,SNAP25,HECW1,ZNF423,SPTB,ATP10B,ICAM5,TNS1,TRPM2,DNALI1" Drug CID000002783 clenbuterol Stitch 2.24E-05 1.00E+00 3.14E-04 3.57E-03 42 142 "ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,MYH7B,ARHGDIG,CAST,ASIC3,MYL6B,CS,GSDME,DMD,RAPGEF4,IGF1,MDFI,MEF2C,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NEUROD1,MYH14,RPS6KA2,SAFB,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,MYO18A,SCN3B,TAC1,PDIA2,NUP214" Drug CID005311256 AC1NSKBB Stitch 2.27E-05 1.00E+00 3.18E-04 3.62E-03 9 13 "GRIA4,GRIK2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug CID006603977 Psora-4 Stitch 2.27E-05 1.00E+00 3.18E-04 3.62E-03 9 13 "KCNA1,KCNA2,KCNA4,KCNC1,KCNC2,KCND2,KCNH2,KCNN3,SCN2A" Drug CID000002396 GF109203X Stitch 2.39E-05 1.00E+00 3.35E-04 3.81E-03 83 342 "ADCY5,ADCY6,ADCY8,ADORA1,ADRA1B,AGT,PLA2G6,APP,BCL2L2,BTK,CACNA1A,CACNA1B,CACNA1E,CALM1,CCKBR,ARHGEF1,LRBA,CHRM1,CLCN3,SLC4A7,NCAN,PLCXD3,MAML1,DAPK3,EDN1,EDNRA,EDNRB,EGFR,ERBB4,PTK2B,FOXO3,GRIA4,PLCD4,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MYLK2,KCNA1,KCNH2,STMN1,ASPRV1,NPY,P2RY1,PDPK1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,PTHLH,PTH1R,PTK2,RGS3,S100B,MAPK12,SCG5,SLC1A2,SLC1A3,SLC2A5,PLCB1,TMPO,TRPC1,PITPNB,VLDLR,PLD4,NUP214" Drug CID000004507 nitrendipine Stitch 2.40E-05 1.00E+00 3.37E-04 3.83E-03 32 98 "ADCY8,AGT,APP,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CACNA2D2,ABCG2,EDN1,EDN3,EDNRA,CACNG7,CACNG3,CACNG2,GRIK1,MAP4K5,HBA1,NPPA,ABCB1,PKD1,RYR1,RYR3,TPCN2,SLC30A4" Drug 4450_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 3.38E-04 3.85E-03 52 189 "DPF1,GRAMD1B,PKP4,CDC14B,KSR1,LDLRAD4,HAP1,CACNA2D2,EPS15L1,ZFYVE9,CTH,EDRF1,GIT2,DCT,SMG7,ARNT2,CDON,EDN1,SEMA3D,GAB1,GLI2,GPD1,SYNPO,IL6ST,KCNF1,KCNH2,MMP16,NACA,NTRK3,OXTR,PDE1C,PDE4B,PLP1,MBOAT7,PTN,ACSS3,CCDC40,RGS4,TCP11L1,HSPA4L,DOCK10,CNKSR2,SLN,PDZD2,ZC3H13,AJAP1,ACSBG1,SYT1,TBL1X,TCF4,CDK20,SF1" Drug 7537_UP CP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 3.38E-04 3.85E-03 52 189 "ASIC1,CDC42BPA,CNTNAP1,ALDH4A1,ADGRB2,NRP2,SCAPER,MYRF,CFAP410,MAP7,WHRN,CRY2,CTH,PITPNC1,CNIH3,ARNT2,TRAPPC9,MRNIP,EN2,EPHA5,CDKL3,PTK2B,OGA,SRCAP,USP19,TXNL4A,HTATSF1,POLL,PRRC2B,IL11RA,DIPK1A,CNOT4,PAK3,SMOX,PRPH,CNNM2,PTHLH,KIF16B,FAM214B,BEX1,ARHGAP26,DDN,PLCB1,SYT1,ASTN2,ATP11A,EXOC7,TCF4,SZT2,AHCYL2,MVB12B,RNF146" Drug 1742_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 2.41E-05 1.00E+00 3.38E-04 3.85E-03 52 189 "ADCY6,ADD3,MTUS1,ALCAM,CNTNAP1,CDK13,MARK4,RIPK1,CFLAR,CD86,SOCS6,ZFYVE9,FAM189A2,ARMC8,CSF1R,PPP1R16B,CTNND1,DOCK4,HP1BP3,KIAA0753,TRAPPC9,SIDT2,FAM13A,MRNIP,ACSL4,TUBB4A,MALT1,GRIA4,MPP2,NF1,OLR1,PALM,PDE4B,GPSM2,SMOX,MBOAT7,RNASEL,SATB1,SH3BP2,BTBD3,LIMS2,USP33,TSPYL2,SAMSN1,PLCB1,EXOC7,TBL1X,SLC44A1,PARD3,UCHL1,GDPD5,MPPE1" Drug CID000004819 pilocarpine- Stitch 2.42E-05 1.00E+00 3.39E-04 3.86E-03 43 147 "ACHE,SLC12A5,ADRA1B,ADRB2,SPARCL1,AMT,BCHE,CA4,CA12,CALB1,CALB2,CCK,ENTPD2,CHRM1,CHRNA4,CHRNB2,CRYBB1,DMPK,DRD1,GABRA4,GAD1,GAD2,GFAP,GRIA1,GRIA2,GRIK1,GRIK3,GRIK4,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,OLFM3,NPY,NTRK2,PROX1,SLC6A1,MLST8,TRH,SLC17A7" Drug ctd:D024505 Tocopherols CTD 2.45E-05 1.00E+00 3.42E-04 3.89E-03 27 77 "SYT13,APP,ATP1A2,CDK5R1,CAMK2G,CSF1R,SV2A,FGF1,FGFR1,CPLX2,CPLX1,GRIA2,GRIN1,PPP3CA,PTPRO,RAB3A,NAPB,SNCB,SNCA,STX1A,STXBP1,SYT11,VAMP1,SYN1,SYN2,SYP,TTC3" Drug CID000001228 C-PP Stitch 2.45E-05 1.00E+00 3.43E-04 3.90E-03 14 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug CID000060839 aptiganel Stitch 2.45E-05 1.00E+00 3.43E-04 3.90E-03 14 28 "GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 7073_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.48E-05 1.00E+00 3.47E-04 3.95E-03 49 175 "ADRB2,ARNTL,ST3GAL5,CLU,NMT2,ABCG1,PDE4DIP,CTH,DNAJC6,PLPPR4,PARD6A,EFNB3,RGS17,F3,TBC1D16,TAOK3,ATP8A1,TESK2,BAIAP2,PDLIM5,FYN,GLS,GUCY1B1,KIF5C,MAPT,MMP16,TAGLN3,PALM,PCDH9,SERPINI1,PIK3CD,RETREG1,PRPH,RBBP6,RGS4,SH3GL3,KDM4B,BEX1,SPTAN1,RGL1,SYT11,SYT1,KAZN,KIAA0930,ARHGEF12,SSBP2,MICAL1,TRIM9,DPF3" Drug CID000072032 2-(aminomethyl)pyrrolidine Stitch 2.49E-05 1.00E+00 3.48E-04 3.96E-03 46 161 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CBS,P2RX6,ENTPD2,LRBA,PLCXD3,LPAR6,ATP2C1,GCK,GFAP,KCNMB4,GPR17,LPAR4,GPR26,GPR34,PLCD4,MAP4K5,GPR45,HTR5A,KCNMA1,P2RY13,NOS1,NPY,P2RX7,P2RY1,PLCB2,PLCD1,PRKACB,MAPK3,MAPK4,MAPK7,PLCB1,P2RY12" Drug CID000004605 nsc25485 Stitch 2.50E-05 1.00E+00 3.49E-04 3.97E-03 77 312 "ADCY2,ADCY5,ADCY6,ADCY8,ADD1,SLC24A4,AGT,NT5C3B,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BLM,CA4,CA12,CACNA2D1,CALM1,CCK,CBFA2T2,ENTPD2,ASIC3,SLC24A2,PLCXD3,BOC,SLC12A6,EDN1,EDN3,TMTC1,ATP2C1,FYN,PLCD4,TNFAIP8L3,HNMT,IGF1,LIG4,MATK,MTR,NBL1,NPPA,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,DUSP15,RYR1,SCN4B,SCNN1D,SLA,SLC6A7,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC12A2,SLC14A1,SCN3B,PLCB1,TAC1,NSD1,PIK3R5,SLC38A1" Drug 5755_DN Racecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "RALGAPA1,APLP1,ALDH7A1,BTRC,CFAP410,CBFA2T2,CRLF1,DNAJB5,TCEAL2,TOX,MFAP3L,SGSM2,SIDT2,EIF4G2,TENM1,PLEKHO1,STX2,ETV1,EZH1,PNMA2,B4GALNT1,AHDC1,USP19,GLYR1,TDRKH,KCNH2,MIA2,ZNF862,NEK1,RETREG1,NLE1,SAMD9,RAB3A,SUGCT,ZNF671,RPS6KA2,MRAS,SH3BGR,FAM102A,SLC2A5,LIMS2,CCDC88A,SNCA,MAPK8IP3,CEP68,ZEB1,TNS2,CABIN1,ZNF74,NDRG4,REEP1,MAP3K12,EPM2A" Drug 5855_UP Harmine hydrochloride [343-27-1]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "SPARCL1,CDK13,N4BP2L1,ADAM23,SRSF11,SOCS6,ARHGAP22,NRXN3,ZFYVE9,CREM,SH2B1,HAPLN1,MICAL2,PDE4DIP,C2CD2L,CDKL3,VPS26C,RACK1,GAD2,HBS1L,C1QL1,GLYR1,GLS,GPR19,GPR37,KIT,NELL1,NF1,NOVA1,NTRK2,PPM1B,PRKAR1B,MAPK7,TMEM231,MYH14,ROM1,FBXW7,RPS20,SCG5,ASAP3,ANKRD6,KDM4D,SNAP25,ZBTB43,ATP10B,ZFPM2,CBX5,VIPR2,WIPF1,WNK1,PRDM2,KCNAB1,DPF3" Drug 3284_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ABHD6,NDRG2,MRTFA,CDC42BPA,APC,CDC14B,PPP4R4,PLA2G4C,CDK13,RASL11B,ALDH4A1,MTMR3,ARHGEF1,NEURL1,FOXN3,AKAP7,IFFO1,CSF1R,ATRNL1,BRINP1,TRAPPC9,EDNRA,ING4,TNK2,ATP8A1,TRAF3IP2,GNG3,NR3C1,ATXN2L,IL6R,IL11RA,NF1,NTRK2,CEP41,PRKAR1B,MAPK8,PTAFR,ELOVL2,FAM120C,FAT4,ASAP3,SLC9A5,SLC11A1,SNCA,SS18,INKA2,ASTN2,POPDC3,TRPC1,OSBP2,VAV2,WIPF1,LAMP5" Drug 4973_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ADORA2A,DOC2A,ASPH,CFLAR,SYNJ2,SCAPER,CACNA1D,DZIP3,TBC1D5,MED12,DTNA,MAMLD1,EDNRA,HIPK3,EFNA3,EIF5,EPB41L1,COQ7,BAIAP2,PRELID3A,GABRA2,INPP5K,GLYR1,POLL,GRIK5,ATXN2L,IGSF1,MAPT,MBD1,MPP2,GIT1,NF1,NUMA1,PDE4A,PLCD1,PTPRE,RAB3IL1,ARHGEF10L,WLS,FOXRED2,ZNF821,SMTN,BTBD7,SMARCA4,WDTC1,VPS13A,ASTN2,ROBO3,KIAA0930,TRIM2,VIPR2,WNK1,KAT6A" Drug 6081_DN Avermectin B1 [71751-41-2]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ABHD6,ALCAM,BIN1,BCAS1,CDK13,MARK4,CADM3,SYNJ1,FUBP1,MTMR3,CACNA1I,CAMK2B,CBFA2T2,SRSF11,VAX2,CRY2,SOCS5,SDC3,DAPK3,TMCC2,DTNA,EFNA3,ING4,MRNIP,NCALD,FECH,RAB30,GPR37,CACFD1,ELOVL5,HNMT,INPP5B,KCNMA1,KPNA5,MAP4,MATK,MID1,PPP2R2B,MAPK7,ZNF821,SLC1A7,FAM214B,BTBD7,SLC20A2,EMC1,ARHGAP26,TROVE2,ELOVL4,SYN2,TACC1,EXOC7,SLC44A1,WIPF1" Drug 6623_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "DPF1,SLC12A5,ALK,CADM3,ATP6V0A1,SYNJ1,SCAPER,CACNG1,CHRNB2,CNR1,FEZ1,SEC14L5,EDIL3,EFNA3,ELN,FGF1,FOXG1,PRELID3A,GFER,GRIA1,KLF12,ICA1,ITPKA,LAMA2,MATN3,ADAM22,NF1,PCDH9,DUSP26,MAPK8,CNNM2,PTN,C1orf54,RGS4,IL17RB,SH3BP2,ASAP3,NTNG1,SLC2A5,ZNF334,BEX1,SPTB,CDK19,NACAD,PHLDB1,COBL,TEX15,ZNF34,ICAM5,PRMT8,ZNF24,ZNF74,PARP6" Drug 4786_UP Atovaquone [95233-18-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ADCY6,FZD9,KIDINS220,SEMA6A,CDC42BPA,APC,GAS7,N4BP2L1,ADGRB3,CACNA1I,BSN,BTRC,CA4,CACNG1,GPR37L1,TAOK2,ZFYVE9,CNTFR,CSF1,RGS6,VCAN,DCC,RABGAP1L,SGK2,F5,ACSL4,ZNF589,AFF2,GCNT2,GPR75,POLL,GRIK2,INPP1,AFDN,MMP17,NF1,ENPP2,CDK14,ZSCAN32,KHDRBS2,FRMPD1,PKNOX2,IZUMO4,HECW1,SPP1,ATP10B,ZC4H2,EXOC7,THBS4,TRPC3,ZNF711,STMN4,PHTF2" Drug 4163_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "NDRG2,NME5,C1QTNF3,EPB41L5,SYNJ2,CBFA2T2,CACNA2D2,QKI,HOMER3,MICAL2,SIPA1L1,DZIP3,DBT,MFAP3L,DTNA,EFNB3,ING4,DLC1,KIAA1109,FGFR1,ZMYND11,SEPT9,SPIN1,MSL3,GNG4,GPD2,INPP5B,KCNF1,NPTX1,PDE3B,LRP12,MBOAT7,PRKAR1B,GRAMD1C,RAB3IL1,PLEKHB2,MSANTD2,ROM1,AP1AR,DOK5,CLSTN2,TACC1,KAZN,EXOC7,PSD3,PCDHA6,DICER1,AP4E1,TMPO,PARD3,FAM155A,UCHL1,WNK1" Drug 6739_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "AGT,APAF1,KCNAB2,GAS7,SLC4A4,SLC2A11,NRP2,SCAPER,CDC42,CDO1,CLCN4,MFAP3L,SV2B,NTM,DTNA,ECM2,DYRK1A,HIPK3,ING4,ELAVL3,COQ7,ETV1,CORO2B,FGF1,FGFR1,AFF2,DCTN2,HBS1L,GATM,KCNMB4,CNTRL,AP4S1,ELOVL5,IL12A,KCND3,KITLG,P2RY13,CLDN11,PAH,PDE3B,SPATA6,ELOVL2,TMEM231,RGS12,ROM1,ZFP30,SLC2A5,TBCEL,TMPO,SEZ6L,LAT2,PHTF2,CAMK1G" Drug 2055_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "SLC12A5,ADORA1,AMH,AMPD3,ALDH7A1,KSR1,BMP7,CACNA1I,C5,BAIAP3,CFAP410,CREB5,CSF1,TENM4,RIMS3,DTNA,EGFR,MRNIP,MTSS1L,F5,SEMA4D,SIGLEC8,GLI2,MSL3,POLL,GNAO1,GPM6B,GPR17,GPR37,KCNJ5,ADAM22,MSR1,MYO7A,P2RY13,PDE4D,RETREG1,PRKAR1B,RAD52,KHDRBS2,RFX2,STUM,SLA,SLC20A2,DOP1A,SPTB,DDN,CLSTN2,IQCE,ZMYND8,OSBP2,MAP3K12,EVI5,SLC17A7" Drug 5050_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ASIC1,ADRA1D,C1QTNF1,TRMT9B,EPB41L5,APLP1,LGR5,CDC14B,TAOK2,RAB28,NRG2,ENTPD4,HAPLN1,CSF1R,ARHGAP24,KLHL3,ATN1,MRNIP,CDKL3,BAIAP2,SCARA3,SEPT9,SRCAP,GRM1,KIF2A,KIF5C,MAPT,MEF2C,MT1M,PDE1C,CCSER2,PLXNB1,MAPK7,ZSCAN2,TMEM231,RPS6KA2,PAQR6,RXRA,FNDC3A,PPP4R3A,SIRT2,FNBP1,SYT11,ATP11A,FBXW11,TIAM1,TRIO,OSBP2,LMF1,WIPF1,MAP3K12,EVI5,KAT6A" Drug 6705_DN Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "MRTFA,BIN1,APC,ASPH,KIF1A,CANX,KRIT1,ARHGEF2,CHM,QKI,DZIP3,TM9SF4,TBC1D5,CHRDL1,FCF1,MBNL2,VPS26C,ZNF589,FGFR1,ANKFY1,TRMO,GLS,CNTRL,DIPK1A,LIG4,PLCD1,POLR2F,PEX5,RAB5B,RAD52,CLIP1,MAPK12,FUZ,PPP4R3A,ELMO2,ZNF667,LIMCH1,NMNAT2,ZBTB43,SS18,NXT2,IQCE,SYNE1,TMEM121,TPM2,TRIO,NSD2,CLDND1,XRCC4,UBE3B,KAT6A,SMIM8,PHTF2" Drug 3604_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "LTBP4,AMT,APBB2,ATM,STX16,ALDH7A1,SYNJ2,CA4,CAMK2G,CBFA2T2,NEURL1,ADGRG1,CLCN3,PDE4DIP,SDC3,ARHGEF4,KIAA0586,EXOG,HIPK3,EFNA3,PHF20L1,SUGP2,PLEKHO1,ENO2,COQ7,F3,ZNF589,ALDH1L1,USP19,PADI2,ICA1,KPNA5,MIA2,LYRM9,NF1,PLCD1,FSD1,WDR25,GSTCD,ROM1,PPP4R3A,BTBD7,COA1,CDK5RAP2,SNCA,WDTC1,KDM4C,IQSEC2,CLSTN2,TBCEL,SLC44A1,MICAL1,WNK1" Drug 2827_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ADORA1,SEMA6A,MRTFA,BIN1,SEMA7A,MARK4,ATM,SLC4A4,CFLAR,BTRC,CAMK2B,HIP1R,ARHGEF2,ADGRG1,FADS2,TCEAL2,CSF1R,DAPK3,TRAPPC9,DTNB,CNNM1,TNK2,C3orf18,KCNMB2,EZH1,CORO2B,AFF2,SEPT9,RND1,ITPKA,KCNQ3,KHK,MAOB,MEF2C,MYO7A,NDUFA5,NNAT,OMG,KCNK10,PLCD1,LRP12,MINDY2,RPS6KA2,SH3BP2,SLC1A7,CXXC4,NPAS3,ATP11A,WSCD1,DMXL2,CHST8,CABIN1,GDPD5" Drug 4474_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "AMPD3,APAF1,CCDC181,NRP2,ST3GAL5,CACNA1I,CFAP410,RUNX1T1,DCLK1,CHN2,TAOK2,LHX2,SLC22A6,RAB26,AKAP7,COL9A3,CRMP1,ARHGEF4,CTIF,ETV1,DLC1,DCTN2,FYB1,ZNF44,SIGLEC8,NEU3,GPD2,GRIK5,GUCY1A2,LAMA2,LIFR,MDFI,KITLG,MOBP,CDK18,PDE3B,PFKFB4,PIK3CD,ELOVL2,ZSCAN2,SUGCT,FBXW7,ZNF671,KANSL3,TSNAXIP1,PHLDB1,PLCB1,MCF2L,TIMP4,TNS1,FLRT2,VAV2,CA10" Drug 7545_DN semustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "RALGAPA1,ACTN1,AP2A2,APC,MARCH3,ARHGEF1,LHX2,CLCN4,SULT4A1,NIPBL,IQCK,SLC4A7,SLC4A8,NCOR2,CSF1,SDC3,DCAF4,RASSF2,DNAJC6,SPOCK3,DLG3,EFNA3,SORBS3,EFCAB2,DENND2A,SIGLEC8,SYT17,GBX2,KIF5C,MAPT,MATN3,MN1,NEK1,NF1,NFYA,NPR2,KCNK10,PLXNB1,BCAS3,PTX3,FAT4,NEK11,SLC14A1,EMC1,ZEB1,GPR161,TPM2,UGT8,WNT7A,ZNF711,MAP3K12,MVB12B,EPM2A" Drug 4159_DN "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ACTN2,NDRG2,KIDINS220,APBA2,ALDH4A1,SYNJ1,SLC25A14,CCNT1,CLGN,SLIT2,TPP1,QKI,CRY2,SNCAIP,FAM169A,DCAF8,DBT,PARD6A,DTNA,APH1A,PLXNC1,DLC1,ZNF589,PRELID3A,KHDRBS3,TXNL4A,GLYR1,GNG3,GPER1,ITIH2,KHK,ADAM22,NEK1,NF1,NFYA,NUMA1,PDE3B,LRP12,MINDY2,MAPK10,PTHLH,PLEKHB2,ATG16L1,ZDHHC14,SH3BP2,SH3GL3,CDK19,PLCB1,SLC44A1,TMPO,ZMYND8,SYNC,PRDM2" Drug 2299_UP Kawain [500-64-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "NME5,ALK,GAS7,PRX,PTCH2,BTRC,CAMK2B,NRXN2,WHRN,CTIF,KLHL3,ST8SIA3,CALCRL,SPEG,CACNG2,ZNF589,OLFM1,FOLR2,GPR153,GAB1,SIGLEC8,DISC1,SEPT9,GFER,LYVE1,GRIK2,IFI16,ITIH2,KIF5A,LRP1B,CD200,MSI1,NCAM1,NEK1,TNPO2,FAM120C,CCDC40,ZMAT4,RFX2,TRIM46,CNKSR2,MAPK8IP3,ARC,SZT2,TPM2,CHST5,FAM155A,LAT2,SPHK2,ADAMTS9,KCNAB1,HRASLS,SENP7" Drug 3854_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "NDRG2,SEMA7A,APBA2,PPP4R4,PLA2G4C,ASPH,STX16,CACNB2,CAMK2B,ADGRG1,LHX2,EPS15L1,STOML1,FADS2,SULT4A1,NCOR2,SNCAIP,RIMS3,DAPK3,SPOCK2,NR1D2,DTNA,DYRK1A,FCF1,EIF4G2,HPCAL4,C1orf61,AGAP2,NSG1,GDF9,GLYR1,HTATSF1,GSN,IL6ST,KCNJ5,LSS,MGAT3,KITLG,MMP17,PNMA3,TNPO2,LRRN3,RPS20,KCNIP1,ZFP2,PPP4R3A,SHANK2,HECW1,GPR161,WIPF1,ZNF24,PARP11,HRASLS" Drug 4425_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.51E-05 1.00E+00 3.49E-04 3.97E-03 53 194 "ABHD6,AMPD3,AMT,CNTNAP1,GAS7,EIF4G3,ALDH7A1,CADM3,MTMR2,LDLRAD4,CDC42,SLC4A7,CPS1,SIPA1L1,SEC14L5,RASSF2,RIMS3,SPOCK2,EXOG,DNAJB6,EFNA3,ING4,VPS13B,FHL1,TPK1,GRM1,ITIH2,KIT,KPNA5,MOBP,ZNF862,PLCD1,MAPK7,C1orf54,RGS10,MYH14,SH3BP2,PREX2,FAM214B,CCDC88A,ZHX3,SPTAN1,ZBTB43,CLSTN2,DMXL2,PCDHGA10,ARHGEF12,TRPC1,HIRA,FLRT2,VIPR2,LAT2,EMSY" Drug CID000003667 IAA-94 Stitch 2.55E-05 1.00E+00 3.53E-04 4.02E-03 23 61 "ACLY,AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CAST,CACNA2D2,EDN1,CACNG7,CACNG2,PCSK1,BEST3,PKD1,RYR1,RYR3,SLC12A2" Drug CID000001345 PK11195 Stitch 2.55E-05 1.00E+00 3.53E-04 4.02E-03 18 42 "ALDH7A1,RIPK1,CACNA2D1,CBR1,DBI,ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,ATP8A2,GFAP,PRPH,SARS,ZEB1,HPS4" Drug 4982_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "MRTFA,CNTNAP1,APBA2,FAM131A,CDK13,ASPH,CDK5R1,MTMR3,ADGRG1,CHM,HOMER3,CRY2,CSF1R,CSNK1E,NOS1AP,EXOG,EDIL3,DMTN,PIPOX,KIAA1109,FOXG1,CAMKK2,ALDH1L1,USP19,GLYR1,GPER1,GRM1,GRM7,HRH3,KCNH2,KIT,KPNA5,MMP16,NNAT,PCBP3,NUCB1,PLEC,PLXNB1,PPP5C,PRKAR1B,PTHLH,ELOVL2,CCDC40,KLHL11,RNASE1,EMID1,FUZ,WDTC1,TSPYL2,TBCEL,PCDHA5,WIPF1,NSD2,HPS4" Drug 6105_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADORA2A,ALK,ANK2,CNTNAP1,CCDC181,ALDH7A1,RGS9,CACNG1,THSD7A,CDH2,CDH18,DNAJB5,IFFO1,HAPLN1,DGKG,BRINP1,CDON,DYRK1A,EFNB3,LRRC23,IGSF6,EFCAB2,SORBS1,NSG1,GABRA2,HBS1L,SRCAP,LPAR4,GRK4,GSTM5,GUCY1A2,ATXN2L,KLF12,KCNH2,ZNF862,NF1,NOVA1,NTRK2,PPP5C,MAPK8,ZMAT4,KCTD17,KLHDC8A,TCP11L1,SLC11A1,ARC,DOCK9,PHF24,TRH,PLPPR2,WIPF1,HRASLS,PAK5,JPH3" Drug 6336_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,ADRA1D,MTUS1,BIN1,PPP4R4,MARK4,CFLAR,SYNJ2,CACNG1,PLAA,AKAP5,SH2B1,CSF1R,CNTNAP2,MYEF2,DTNA,ABCC9,SGK2,EFNB3,COQ7,DLC1,ST3GAL6,FGF1,ALDH1L1,GCNT2,C1QL1,GLYR1,SPACA9,SCIN,INPP5B,MDFI,ADAM22,NKX2-2,PBX1,POU3F2,PPP2R2B,SNRK,PTPRH,FAM184A,CRTAC1,RGS7,TCP11L1,SYNDIG1,SLC1A7,PEX26,IFT122,KDM4B,WDTC1,TACR1,TRIM2,LMF1,XRCC4,KCNAB1,NUP214" Drug 6295_UP Aminophylline [317-34-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,ASIC1,ACTN2,ADCY6,KIDINS220,NME5,ALK,MRTFA,AMPH,APC,GAS7,CFLAR,SCAPER,CACNA1I,WHRN,COL9A2,CSF1,AK5,CDON,TOM1,DUSP9,EFNA3,PLXNC1,PLEKHO1,CORO2B,TRAF3IP2,DENND2A,ZNF276,LPAR4,PTGDR2,HSF2,IL6ST,KIFC3,VWA5A,MAPT,GIT1,CNOT4,PDE3B,SAMD9,GDPD2,GSTCD,RPS6KA2,SUPT20H,SH3BP2,CNKSR2,SLC20A2,TMCC1,SPTB,DDN,ARHGEF9,RPRM,NT5M,KCNAB1,PAK5" Drug 2518_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADD2,BBOX1,DOC2A,APAF1,APBB2,APOC1,PLA2G4C,CADM3,AZGP1,LDLRAD4,CHRNB2,SLC22A6,HAPLN1,MICAL2,PDE4DIP,DZIP3,USP6NL,SV2B,HS3ST2,ATN1,E2F5,SEZ6L2,EDN3,DLC1,KIAA1109,AFF2,GAD2,GATM,C1QL1,PRUNE2,STMN2,GUCY1A2,KLF12,ICA1,KCND3,KCNQ3,KIF5A,MSI1,PCDH9,PCSK5,CCSER2,FSD1,KCNIP1,RASA3,SH3BP2,PPM1E,FERMT1,PDZD2,SPTAN1,MCF2L,TMOD1,SSBP2,TUBB1,SCG2" Drug 4191_DN Conessine [546-06-5]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,AP2A2,PLA2G6,APP,LGR5,ARHGDIG,BRINP2,CACNB2,KALRN,ARHGEF1,CDH8,ARHGAP22,LHX2,RAB28,LY86,ENTPD4,SLITRK5,TBC1D5,MFAP3L,MBNL2,ZNF391,ETV1,VPS26C,F5,FGFR1,MSL3,GRIK2,GRM1,SHISAL1,JAK2,KCNF1,PAK3,PDE4D,RETREG1,ST8SIA5,ELOVL2,RGS4,RGS10,MRAS,BCAN,SLC1A7,KANSL3,SLC11A1,SOX2,SEPT8,SLC44A1,THRA,TIMP4,RUNDC3B,VGF,LMF1,REEP1,KCNAB1,PLSCR4" Drug 61_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "RBM10,ACTN1,KIDINS220,ASCL1,ASPH,CAPN3,HIP1R,SCARB1,CDH8,CHGB,TMEM184B,C2CD2,HINFP,JAKMIP2,TSPAN5,OPTN,EFNB3,PLEKHA1,ETV1,FGF1,PRKAG2,PCYOX1,TRAF3IP2,B4GALNT1,GFER,GLS,GRIA4,GRIN1,BTN2A1,SOX21,SLC2A6,IGSF1,MYO7A,NFYA,NTRK3,NUCB2,FSD1,PRKAB2,PRODH,RIPOR1,CCDC40,C1orf54,RNASE1,SYNDIG1,RXRG,SLA,ELMO2,SMARCC2,NMNAT2,MYCBP2,ATP11A,TAL1,WIPF1,UBE3B" Drug 2224_DN Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG3,NDRG2,KIDINS220,C1QTNF3,AMPD3,APBA2,PLA2G4C,NCOA1,ALDH4A1,ST3GAL5,ARHGEF1,ARHGAP33,TPP1,FAM189A2,CREM,CSF1R,DAPK3,CTIF,MFAP3L,SORBS3,DMTN,ZNF589,HBS1L,SEPT9,GLYR1,GNG4,TDRKH,GRIK5,VWA5A,MIA2,MPP2,MSI1,MYO7A,ZSCAN2,RGS10,RNASEL,FNDC3A,SYBU,PEX26,SOX3,EMC1,KDM4C,PLCB1,ARC,MTCL1,MCF2L,TRIM2,PSD3,ARHGEF12,TMOD1,SPHK2,SYNC,MAP3K12,SEMA3B" Drug 2563_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "SYN3,AMH,AMPD3,BIN1,ANK3,PPFIA4,MPDZ,CD86,CRLF1,CHRNA4,ZFYVE9,CNTFR,CREM,RGS6,SLITRK5,DRP2,EDN3,FAM13A,EBI3,ENO2,ARMCX1,FOXG1,GPR75,GNAL,STON1,ADAMTS8,GUCY1B1,GPR45,HTR5A,TJAP1,KCNC1,KCNF1,MDFI,MN1,MOBP,MPP2,MX1,PFKFB3,PKN2,RASGRF1,RGS12,TCP11L1,CCDC92,PALLD,IZUMO4,JMJD6,ARHGEF9,SZT2,TRO,FLRT1,ZBTB38,ADAMTS9,PARP11,GAN" Drug 5095_DN Thiocolchicoside [602-41-5]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "MTUS1,CNTNAP1,KCNAB2,APBB2,ARHGAP5,ASPH,ZBTB10,SLC4A4,ALDH7A1,KRIT1,LARGE1,SRSF11,SOCS6,RAB28,STOML1,HOMER3,BAG4,CREM,CSNK1E,SMG7,AK5,DLG3,DYNC1I1,DENND4A,BAIAP2,SMC2,CSPG5,AGFG1,JAK2,KCNN1,KIF2A,SLC11A2,PBX1,PIK3R1,PTCH1,PID1,SEC61A2,KIRREL1,PPP1R9A,AMBRA1,SHANK2,SLC14A1,SNCA,SPATA7,EMC1,BEX1,PHLDB1,BHLHB9,TRIO,HIRA,LMF1,EVI5,MVB12B,AAAS" Drug 1403_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,APBA2,CDK13,CADM3,N4BP2L1,KRIT1,RAB26,C2CD2,CRYM,ARHGAP32,FEM1B,EFNB3,TMEM35A,EPB41L2,ERBB2,CDKL3,DISC1,SRCAP,PCDH17,GSTM5,PADI2,MAN1B1,KLF12,KCNJ9,KIF2A,MAP4,MMP17,GIT1,NFE2L2,NPY,NUCB1,OMG,RETREG1,PLCD1,ARID4A,RGS12,ARHGEF10L,RNH1,CLIP1,SBF1,ZKSCAN3,DOK5,ZSWIM8,THSD1,LARP4,ARHGEF12,HEY1,CBX5,SEZ6L,TPM3,WBP2,WIPF1,TRIM9,MKRN3" Drug 6325_UP Molsidomine [25717-80-0]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "LTBP4,SEMA4G,PPP4R4,MARCH3,ATP1A3,BMP7,CHM,B4GALT6,NRXN3,DNAJB5,ARMC8,WHRN,NCOR2,PDE4DIP,CNTNAP2,PHF14,CTNND2,RIMS3,CTIF,SIDT2,COQ7,KAT8,DCTN2,PNMA2,OGA,GABRA1,GRIK5,INPP5B,KCNF1,KCNJ5,MIA2,MMP16,MYH3,NF1,NPTX1,PBX1,RETREG1,EPN1,PEX5,RAD52,DZIP1,PREX2,ELMO2,IFT122,NPAS3,DDN,INKA2,CEP68,ARHGEF9,FBXW11,ARHGEF12,TRIO,XRCC4,ZNF45" Drug 3299_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "KLRC4,MRTFA,ANK2,APC,APLP1,ST3GAL5,BTRC,CFAP410,CAMK2G,SULT4A1,ARHGEF6,SNCAIP,PDE4DIP,DZIP3,SEC14L5,DOCK4,JAKMIP2,TUBB4A,FECH,FGFR1,FOXG1,C1orf61,TPK1,CSDC2,GLS,POLL,GNG4,GRIK3,NR3C1,ATXN2L,HLF,MAOB,MDM4,ADAM22,PLTP,TMEM231,SEC61A2,ZFHX4,RYR1,ITSN1,SLC1A7,CXXC4,SCN3B,ZC3H13,ST5,SYN2,KIAA1107,SYNE1,ARHGEF12,CHST8,GPR161,CDK20,RUNDC3B,DNALI1" Drug 4986_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "DPF1,PLA2G6,SEMA6A,MRTFA,AMPD3,ADAM23,ADAM15,BCL7A,CACNA1I,BAIAP3,ARHGEF1,ARHGAP33,HOMER3,CNTN1,TCEAL2,CSF1R,CSNK1E,SIPA1L1,SPOCK2,MFAP3L,DTNA,SIDT2,EFNB3,ELAVL2,CORO2B,FGFR1,GLYR1,GPM6B,ICA1,KCNF1,KCNH2,MAP2,MAP4,NELL2,NF1,RETREG1,ZSCAN32,RGS12,TCP11L1,SEC14L1,SH3GL3,PKNOX2,COA1,ZCCHC24,IQSEC2,RGL1,AJAP1,POPDC3,TNS2,PCDHA5,HIRA,VAV2,ADAMTS9,MPPE1" Drug 4000_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "AMPD3,GAS7,APP,LGR5,PDE8B,MARK4,SYNJ2,LHX2,CLU,DNAJB5,RAB26,HOMER3,COL9A3,AATK,CTIF,BRINP1,MFAP3L,ATN1,EDN1,SIDT2,LPAR6,HSD17B14,FOXG1,CGREF1,FYB1,GAD1,GFER,GRM8,SYNPO,ICA1,SHISAL1,VWA5A,MAPT,ADAM22,ODF2,EPN1,ZCWPW1,RGS10,KIRREL1,PAQR6,TRA2B,FRMPD1,AMBRA1,NLGN1,SLC6A9,LHPP,MAPK8IP3,IQCE,TK2,LILRA4,AMACR,LMF1,REEP1,KCNAB1" Drug 5430_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "RALGAPA1,ADD2,TRMT9B,CNTNAP1,GAS7,PPP4R4,PLA2G4C,DDX3Y,CADM3,N4BP2L1,NRP2,CFAP410,CACNG1,FOXN3,CHRNA4,SLC22A6,AKAP7,RIMS3,DGKG,SPOCK3,HS3ST2,FAM13A,PLXNC1,RCAN2,ERCC2,APC2,CORO2B,FOXG1,SIGLEC8,SOX21,VWA5A,MSI1,NF1,SLCO1C1,TMOD2,PLTP,TRHDE,PTCH1,RAD52,MYH14,FBXW7,ZFP2,OGDHL,KDM4B,SPTAN1,SYT5,TCF4,SZT2,R3HDM1,UBE3A,UCHL1,OSBP2,XRCC4,AP3B2" Drug 4564_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NME5,SYNGR3,CHM,TAOK2,PLAA,DNAJB5,QKI,CHD1L,CTH,ARHGEF4,ARHGAP32,DBT,KLHL3,SMG7,DLG3,EDNRA,EFNA3,RGS17,ERCC2,EZH1,CINP,CGREF1,OGA,FYN,DISC1,POLL,TDRKH,JAK2,KHK,L1CAM,NUMA1,PDE1C,STRN3,CNNM2,SAMD9,PID1,FAM184A,TTLL7,SUGCT,MYH14,ROM1,SH3GL3,ASAP3,CCDC88A,SMARCC2,TMCC1,TNIK,SRPK2,TK2,TMPO,LMF1,NSD2,XRCC4,ZNF711" Drug 5575_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "C1QTNF3,CDC42BPA,EPB41L5,APOC1,CDK10,ARRB1,CAMK2G,CAST,SLC4A8,BAG4,AKAP12,CSNK1E,FAM169A,SDC3,PPP6R2,HDAC4,RIMS3,SGSM2,DMPK,RBM12,STX2,ZNF589,FGFR3,DPYSL4,GART,MAP4,MIA2,PDE3B,RETREG1,FA2H,FSD1,PRKAR1B,FAM192A,SBF1,FBXO11,ABLIM3,PEX26,BTBD7,EMC1,ZBTB43,ELOVL4,PHLDB1,COBL,TACC1,MCF2L,PSD3,AHCYL2,CABIN1,NPL,UBTF,LMF1,WNK1,HPS4,MVB12B" Drug 3718_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,ADRA1D,NME5,LTBP4,CDK10,PPP4R4,DNAH17,ASPH,NRP2,CFAP410,HAP1,CLCN4,CNTFR,CNTNAP2,ERC2,SPOCK2,ECM2,LRRC17,EPHA5,ARMCX1,ATP8A1,C1orf61,SORBS1,NSG1,GAP43,GPR19,GRIA1,GSTM5,SOX21,PTGDR2,IRF8,KCNB1,KIFC3,MMP16,PDE4B,PDGFRA,PFKFB2,NLE1,PURG,LRRN3,PKN2,NKAIN1,FAM184A,SEC61A2,MYH14,PNMA8A,TRIM46,SPTB,KAZN,CHST5,FLRT2,ZBTB14,PRDM2,STMN4" Drug 6640_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "AP2A2,AGT,TRMT9B,AMPD3,PPFIA4,CNTNAP1,LGR5,ATM,CACNA1I,BAIAP3,LDLRAD4,BTRC,CACNB2,CHN2,DNAJB5,CPS1,CSF1,BRINP1,ATN1,CELSR3,MBNL2,TNK2,IGSF6,ZNF549,ETV1,KIAA1109,PNMA2,GAB1,LPAR4,INPP5B,LIFR,MATN3,MDFI,MIA2,MYO6,PPARA,SNRK,RIPOR1,ZCWPW1,ZNF821,LIMS2,SNCA,WDTC1,ARHGAP26,DDN,ZEB1,TK2,ZKSCAN5,OSBP2,PLPPR2,ZNF711,NDRG4,FAM13C,SENP7" Drug 5462_UP Piracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "RALGAPA1,FZD9,ADORA2A,PLA2G6,C1QTNF1,ALK,SEMA7A,PPP4R4,ARHGDIG,CFLAR,CACNB2,CACNG1,HAP1,RUNX1T1,CHN2,CNTN1,AKAP7,COL9A3,CSF1R,VCAN,HDAC4,JAKMIP2,C2CD2L,MED12,EFNA3,PLXNC1,C3orf18,CORO2B,FGFR1,BAIAP2,INPP5K,GNAO1,HNMT,KCNN2,NTRK2,ENPP2,LRP12,TMEM231,ATG16L1,RGS12,KCNIP2,ANKRD6,SLC11A1,SHANK2,SNCA,DOK5,SPTAN1,RGL1,TAC3,SEMA4A,KIAA0930,CLDND1,KCNK12,MPPE1" Drug 5864_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ALAD,CDK13,ALDH4A1,MYRF,CA8,INA,SYNGR3,TPP1,DNAJB5,WHRN,AATK,CSF1R,CTNND2,FRMPD4,MFAP3L,KIAA0753,SMG7,DLG3,EGFR,TENM1,HSD17B14,RASGRP2,DLC1,FOXG1,ERAP1,SEPT9,ALDH1L1,TDRKH,MAN1B1,KHK,PACRG,MDFI,MOBP,PLCD1,PRKAR1B,TMEM231,MYH14,FBXW7,RYR1,SELL,NTNG1,KDM4D,SLC11A1,SNAP25,TNIK,NPAS3,ATP10B,PCDHGB6,ZKSCAN5,LAT2,SPHK2,SLC17A7,PARP11,GAN" Drug 5385_DN Amoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "APBB2,APLP1,PPP4R4,ALDH4A1,SYNJ2,MTMR2,ADGRG1,PDE4DIP,SPATA2,MFAP3L,RHOBTB1,PARD6A,EFNA3,MRNIP,KAT8,ZNF589,FGFR1,BAIAP2,IQCG,GLYR1,GNG4,GPD2,GPER1,CACFD1,NR3C1,IGSF1,KCNJ3,KITLG,MPP2,NF1,STRN3,ELOVL2,FAM120C,PEX5,GTDC1,RGS12,FBXW7,RPS6KA2,ZNF821,ZKSCAN3,KDM4B,ERC1,ST5,INKA2,PLCB1,ATP11A,TRIM2,TNS2,AHCYL2,SLC44A1,PARD3,CABIN1,HIRA,KCNK12" Drug 3678_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "PLA2G6,MRTFA,AMPD3,CDC42BPA,APAF1,SLC4A4,BAIAP3,BTRC,CA12,LARGE1,TAOK2,PICK1,CNTFR,IQCK,ABCG1,PPP6R2,TOX,DAPK3,CNIH3,CDON,DSCAM,ING4,FGF1,GAD2,SYT17,SRCAP,GNAS,GNG4,ELOVL5,INPP5B,KCNB1,KCNJ5,KCNMA1,MYO7A,PC,PRKAR1B,PTPRB,FAM120C,RAP1GAP,TCP11L1,IL17RB,ASAP3,DZIP1,KIF13A,RBM34,SPTAN1,COLGALT2,CEP68,COBL,PARD3,AMACR,RPRM,VAV2,EVI5" Drug 5836_DN Streptozotocin [18883-66-4]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ABHD6,AP2A2,APBB2,APLP1,APP,CASK,PDE8B,LHX2,CLU,WHRN,CSF1,TOX,SPOCK2,RHOBTB1,SIDT2,SORBS3,COQ7,CDKL3,EZH1,F8,DCTN2,TRMO,COPS8,MAN1B1,HNMT,INPP5B,SCAMP5,MYO6,CCSER2,KCTD15,PLCD1,RC3H2,FA2H,TMEM104,PEX5,BSDC1,RIC8B,MCMBP,PAQR6,IL17RB,FAM102A,KIF16B,RAB3GAP1,CDK5RAP2,SNCA,UNC5B,ZBTB43,THSD1,ST5,SYNE2,TRIM2,BHLHB9,CADM1,NAV3" Drug 2235_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADORA3,MRTFA,ATP1A2,CFLAR,BAIAP3,SULT4A1,LY86,SLC4A7,TENM4,GREB1,SPOCK2,RABGAP1L,DNAH9,ST8SIA3,ELN,HSD17B14,NCALD,IGSF6,SPEG,F5,TUBB4A,ATP8A1,FGFR1,EFCAB2,OGA,GAD2,RND1,KLF12,KCNJ5,SMAD1,MN1,ADAM22,ZNF862,NEFM,NELL2,NF1,EPN1,TNPO2,PPARA,GDPD2,RAD52,TMEM206,ASAP3,FAM214B,HECW1,ZC3H13,BEX1,ABCC8,VAMP1,CUX2,NR2E1,VAV2,LAT2,MKRN3" Drug 3095_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ARID1A,ADD2,SEMA6A,SEMA4G,CALB1,INA,P2RX6,CRLF1,CHI3L2,CREM,ABCG1,SIPA1L1,SPOCK2,SV2A,DNM2,EFNB3,TNK2,ETV1,C1orf61,DCTN2,GAD1,MYOZ2,GPR75,GPR19,PCLO,GRIN1,ELOVL5,KHK,MAP4,MGAT3,MSR1,TAGLN3,NPPA,OMG,PFKFB4,CCSER2,PURG,MAPK3,RAD52,TTLL7,PLPPR3,SYNDIG1,GALNT10,CCDC92,DOK5,ST5,TRIM2,TNS1,RBFOX2,LILRA4,SLC13A3,SLC17A7,HRASLS,SSPN" Drug 5408_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ARID1A,ADORA1,GAS7,CAMK2B,CAMK2G,CD86,CDH10,SEC14L5,SPOCK2,DCC,EDNRA,MTSS1L,FOXG1,AGAP2,PRELID3A,RND1,GPM6A,KCNC1,KCND3,KCNN1,MAOB,MMP16,MOBP,ADAM22,NEFH,NEUROD1,OMG,OPCML,CLDN11,PDE3B,SERPINE2,LRP12,MAPK7,MAPK8,PTHLH,PTX3,FAT4,RFX2,RGS4,ZNF821,SUPT20H,BCAN,SLC2A5,SLC11A1,TSNAXIP1,ZHX3,CDK19,PHLDB1,PLCB1,TMOD1,WIPF1,MKRN3,SYNC,SENP7" Drug 1009_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NME5,AK2,C1QTNF3,SYT13,SEMA4G,ARRB1,ALDH4A1,SCARB1,ARHGAP33,ADGRG1,SLC4A8,RCHY1,PDE4DIP,RIMS3,NTM,KBTBD11,SIDT2,EFNA3,VPS13B,ZNF589,SRCAP,GRB10,SLC2A6,JAK2,KIF5A,MAN2A2,MSR1,LYRM9,ZNF862,CDK18,SLC25A23,WDR25,RAB3IL1,RAD51D,CARF,PNMA8A,ROM1,TCP11L1,RXRA,ZNF821,SH3BP2,FAM214B,SLC6A8,ZHX3,TSPYL2,TROVE2,JMJD6,BHLHB9,CABIN1,TRPC1,VAV2,PRDM2,PARP11,NUP214" Drug 7013_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADCY6,MRTFA,APBB2,GAS7,CDK10,PDE8B,MARK4,ALDH7A1,FGF17,ARHGEF1,SCARB1,QKI,FEZ1,PDE4DIP,ARMCX2,DMPK,DTNA,EFNB3,PHF20L1,LRRC23,EFS,RACK1,TPK1,SEPT9,GRB10,MUM1,IL6ST,KCNH2,MAP4,MBD1,NASP,NF1,NFYA,SMOX,CNNM2,WDR25,PTCH1,WLS,SBF1,SH3BP2,PPM1E,LIMCH1,LHPP,ANKRD12,SEMA4A,KIAA1107,TRIM2,PSD3,PARD3,ZKSCAN5,PLPPR2,VAV1,VLDLR,SEMA3B" Drug 7237_DN Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "SRPX,BCAS1,APP,CDC14B,MARCH3,ASPH,ALDH4A1,KIF1A,MAGI1,CRLF1,QKI,FEZ1,CTNND2,DCAF8,TOM1,IRAK4,LRRC23,CDKL3,FECH,BAIAP2,SEMA4D,SRCAP,TXNL4A,COPS8,GNG4,GPR19,GRB10,HNMT,IGSF1,INPP5B,KCNJ3,MAP4,LRP12,SAMD9,RIPOR1,ROM1,NEK11,RPS6KA2,RXRA,FAM192A,FOXRED2,SMTN,ELOVL4,ASTN2,TACC1,TRPC1,ZMYND8,CADM1,VGF,MICAL1,ZBTB14,REEP1,MAP3K12,HPS4" Drug 1473_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,ADORA2A,NLGN4X,AMPD3,APBA2,APC,APP,MARK4,ALDH4A1,ST3GAL5,BAIAP3,ARHGAP33,CRLF1,ZFYVE9,WHRN,COL4A5,GREB1,TMCC2,SHANK1,EDNRA,CELSR3,STX2,ZNF44,IL6ST,KIT,NACA,NF1,SLCO1C1,NOS1,CNOT4,POLG,POU3F4,CCDC40,KCTD17,ZNF365,PPP4R3A,RAB3GAP1,SLC11A1,MAPKBP1,EMC1,PBLD,INKA2,SYT5,PSD3,CRTC1,CHST8,AP4E1,TMOD1,FLRT2,SF1,MAP3K12,NT5M,KCNAB1,RNF170" Drug 3516_UP Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "DPF1,KIAA1324,TRMT9B,AMH,BIN1,ARHGDIG,ATP2B2,HIP1R,ARHGEF1,CACNA2D2,TENM4,SIPA1L1,CNTNAP2,NOS1AP,RASSF2,TRAPPC9,ATN1,SORBS3,TNK2,MTSS1L,CAMKK2,TBR1,GRM3,HPCA,IL6R,BCO1,MYO7A,CAMKV,MAPK7,PTHLH,CCDC40,FAT4,ZNF493,RASGRF1,KHDRBS2,ZMAT4,RGS12,PPP1R9A,ST6GAL1,SYBU,PKNOX2,CXXC4,SNCA,ZNF423,CDK19,MAPK8IP3,EXOC7,CUX2,TK2,PRMT8,TRPC3,ZMYND8,ZFP37,ZIC3" Drug 3220_UP Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "MRTFA,CDC42BPA,KCNAB2,STX16,SYNJ2,BAIAP3,AKAP7,COL9A3,ARHGEF10,SIPA1L1,GREB1,INTS1,DNAJC6,EDNRA,EFNA3,EFNB3,APC2,FGFR1,TRMO,FYB1,GAD1,RAB30,GNAL,GRM1,GRM8,IRAK3,INPP5B,VWA5A,GIT1,TAGLN3,MYCN,MYT1,NEUROD1,NPTX1,NTRK2,CDK18,PDE4A,CDK14,PLCD1,EPN1,PPP5C,PLPPR1,RPS6KA2,SBF1,ASAP3,PREX2,SLN,SORCS3,RPGRIP1L,TMEM121,TNS1,TRH,CLIP2,SLC30A3" Drug 3543_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "KIDINS220,AP2A2,AP1B1,AK2,PLA2G6,AMT,ALDH7A1,BTRC,CFAP410,CA12,CACNG1,CAMK2G,NEURL1,WHRN,CSF1,CTIF,MFAP3L,RUSC2,LRRC23,NCALD,FER,FLNC,GPR153,OGA,DISC1,GLS,GPER1,GRIK5,ATXN2L,GIT1,NF1,NTRK2,PALM,RETREG1,POLG,PPARA,RGS12,ROM1,EMID1,SEMA6D,BTBD7,KIF13A,WDTC1,MAPK8IP3,PHLDB1,ARC,ZEB1,TMEM121,PLPPR2,WNK1,MAP3K12,PRDM2,PCBP4,PHTF2" Drug 2341_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADORA2A,ANK3,PDXK,ARRB1,CAPRIN2,C5,CFAP410,CD38,NEURL1,SULT4A1,CNTN1,CREM,CRY2,KIAA0753,CELSR3,EPB41L1,MTSS1L,FOXG1,GABRA4,SRCAP,FERMT2,GPD2,ATF7,LILRA2,GRIN1,KHK,KIF5A,MAP4,MYCN,NF1,NINJ2,P2RY1,NECAB2,NEK11,SH3BP2,RPH3A,SLCO1A2,KDM4B,ZCCHC24,DOK5,ZSWIM8,IQSEC2,DDN,ATP10B,CLSTN2,SYT5,EXOC7,TNNT1,RBFOX2,CDK20,TRO,XRCC4,TRIM9,MAP3K12" Drug 2144_UP Protoveratrine A [143-57-7]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADCY2,ADORA1,MTUS1,CDC42BPA,APAF1,APBB2,ARRB1,KIF1A,CLCN4,DCAF4,CELSR3,MBNL2,NCALD,CEND1,FGFR1,HPCAL4,FOXG1,PRELID3A,B3GAT1,GAB1,GPR19,GSTM5,ATXN2L,KCNN1,MAP4,MAPT,MEF2C,ZNF862,NOS1,NUMA1,PBX1,PENK,PLCD1,CCDC40,RFX2,RGS4,RGS12,KCTD17,RNASEL,TCP11L1,MAP6D1,SEMA6D,CPEB3,KDM4B,IZUMO4,SPTAN1,TSPYL2,SS18,MAPK8IP3,CRTC1,VGF,SPHK2,KCNAB1,ADAMTSL3" Drug 3180_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "AMPD3,APAF1,CACNG1,THSD7A,HIP1R,MYRIP,SLITRK5,PHF14,DBT,DTNA,HIPK3,SEMA3D,ERBB2,FGF12,HPCAL4,PNMA2,HPGDS,GLS,PRDM5,GRM7,GRM8,HPSE2,HNMT,KITLG,TAGLN3,MX1,PCBP3,PDE4A,PDE4D,GPR85,PIK3CD,PTPRN2,RASGRF1,PRR5L,DOK5,COLGALT2,SSTR2,PLCB1,POPDC3,KIAA1107,PCDHGA1,HIF3A,AP4E1,TIMP4,TK2,DAAM2,TRIO,TRO,VGF,SLC13A3,XRCC4,TRIM9,PRDM2,AP3B2" Drug 7487_DN semustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "SEMA6A,ALCAM,PLA2G4C,SLC4A4,ADGRB1,SYNJ2,BTRC,CA4,CAMK2B,CACNA2D2,VAX2,DNAJB5,QKI,AKAP7,BAG4,CSF1,NOS1AP,CTIF,ATN1,EIF5,STX2,EFEMP1,ATP8A2,CNTRL,SYNPO,ITPKB,JAK2,KIT,LIG4,AFF1,NOS1,PAK3,PLCD1,MYH14,GSTCD,RPS6KA2,ASAP3,BCAN,SHANK2,SOX15,PHLDB1,PLCB1,ARC,TACC1,WSCD1,PCDHA5,TMEM121,HEY2,TMPO,BEX4,TUBB1,SPHK2,EVI5,AP3B2" Drug 5426_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NME5,AK2,ALCAM,MADD,KIF1A,CFLAR,CDK5R1,BAIAP3,CLGN,TAOK2,ABI3BP,CRY2,NCOR1,SIPA1L1,TBC1D5,DAPK3,EXOG,DSCAM,DTNA,EIF4G2,DMTN,FHL1,IQCG,RAB30,IL6ST,INPP5B,MAPT,MBD1,KITLG,LYRM9,NDUFA5,NTRK2,LRP12,MAPK7,MAPK8,ZSCAN32,GTDC1,RNASEL,WLS,SYBU,ANKRD6,PPP4R3A,RBM34,EMC1,MAPK8IP3,KIAA0930,PSD3,TGFBR3,PARD3,RBFOX2,TRPC1,CLDND1,EPM2A,PHTF2" Drug 3576_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,ANK1,KCNAB2,ATP2B2,ATP2B3,CFLAR,SYNJ2,GYG2,CA4,HAP1,CBFA2T2,RCBTB2,TCEAL2,NECTIN3,SNCAIP,ARHGEF10,MICAL2,SDC3,RIMS3,TRAPPC9,DTNA,EDNRB,CNNM1,EFNA3,EFNB3,CHL1,GAD1,TXNL4A,GPM6A,JAK2,KCNH2,SMAD1,CD200,ADAM22,NF1,NFYA,NNAT,RETREG1,LRP12,POU6F1,PRODH,ZNF493,RAVER2,SYBU,PREX2,SLC9A5,SLCO1A2,DOP1A,ARHGAP26,EPB41L3,VAMP1,PLCB1,DMXL2,PSD3" Drug 6164_UP "aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ABAT,ACTN2,AP2A2,DDO,CACNA1I,NEURL1,B4GALT6,CLTB,FAM149A,GPRASP1,DAPK3,SPOCK2,EFNA3,FAM13A,ANKMY1,CEND1,DLC1,C1orf61,B3GAT1,NCKAP1,GFAP,ATF7,GRIA4,NXPH3,HRH3,KCNJ5,ADAM22,MYCN,MYO6,NEFM,NF1,NNAT,NPTX2,OPRL1,PFKFB2,PLCB2,CEP41,CNNM2,CCDC40,RGS12,MYH14,SYNDIG1,SHANK2,LIMCH1,PDZD2,PEG10,ZC3H13,MAPK8IP3,ARC,TAL1,ATP13A2,TRPC1,FAM155A,SLC17A6" Drug 3481_DN Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG3,ADRA1D,APBB2,APOC1,CDK10,SCAPER,CFAP410,CAMK2G,PLEKHB1,TAOK2,TPP1,VAX2,CRY2,CSNK1E,CTH,DSCAM,TOM1,LRRC23,EZH1,ZNF589,FECH,FAM49B,DISC1,GCNT2,LPAR4,ICA1,IPO5,MATK,MIA2,MPP2,NF1,MBOAT7,PTPA,PRPH,TMEM104,PTPRE,PEX5,ZNF821,FBXO11,ANKRD6,LIMCH1,WDTC1,FNBP1,EMC1,CLASP2,SEMA4A,TIAM1,RBFOX2,TPM1,VGF,KCNK12,ZNF45,ST7,PHTF2" Drug 2747_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,APLP1,APOC1,APP,CDK13,ST3GAL5,CACNA1G,CACNA2D1,HAP1,CBFA2T2,CDH8,CDH10,RCBTB2,LHX2,ZFYVE9,LY86,HOMER3,WHRN,SNCAIP,CSF1R,CSNK1E,PARD6A,SRGAP3,SHANK1,DYRK1A,EGFR,EN2,KIAA1109,GCNT2,POLL,GNAS,ATXN2L,KCNH2,NF1,NPR2,OPCML,CLDN11,CDK18,PRKAR1B,PRKCB,MAPK8,ZNF493,ZDHHC14,SEMA6D,SELL,KDM4C,PEG10,ARC,KAZN,TBCEL,CHST8,MICAL1,WIPF1,KAT6A" Drug 254_UP SC-58125; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,ADORA1,AMPD3,BIN1,CDK10,PDXK,ARNTL,CHRD,ATP2B2,AZGP1,CBFA2T2,CLCN4,HOMER3,PCYT1B,NCOR2,PLCH2,SIRPA,DCC,ATN1,ECM2,ING4,ENO2,EFS,SPEG,FGF1,FOLR2,ADAM28,TXNL4A,GRM1,GRM8,FAM107A,NCKAP1L,KCNJ5,PCBP3,PACSIN1,POU3F4,MAPK8,RIPOR1,RAB3A,KHDRBS2,GAL3ST4,RGS12,FAM192A,FOXRED2,RASA3,FRMPD1,FERMT1,ZHX3,SST,KAZN,OBSL1,TNS1,WIPF1,NUP214" Drug 5309_DN Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ABR,ALAD,APP,NCOA1,MTMR9,CDK5R1,SYNJ2,ARHGEF7,MTMR2,CBFA2T2,SCARB1,COL9A2,CLOCK,FEZ1,CSNK1E,CTNND2,INTS1,DBN1,PLEKHA1,FGFR1,ANKFY1,FAM49B,CELF1,GAA,PRRC2B,KIF5C,MEIS1,MITF,MYO9A,OGG1,MINDY2,PRKAR1B,TMEM104,PTK2,CLIP1,NCBP3,ZNF331,FOXRED2,ITSN1,SMTN,SLC15A2,MAPKBP1,TROVE2,SEPT8,PLCB1,TCF12,TRIO,NSD2,SF1,FTSJ1,TFIP11,WIPF2,MPPE1,SMIM8" Drug 4352_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,SEMA6A,ALK,PKP4,CFLAR,C5,NEURL1,ARHGAP33,CSF1,DZIP3,RIMS3,DSCAM,DTNA,HIPK3,EFNB3,ING4,DMTN,STX2,PTK2B,SCARA3,SRCAP,PCDH17,RAB30,STON1,GPR37,GRIK5,KITLG,MMP16,LYRM9,NF1,NOS1,PDE3B,LRP12,MAPK7,ZSCAN32,NEK11,TCP11L1,RASA3,ASAP3,PPP4R3A,CXXC4,SMARCD3,PDZRN3,DOP1A,CLASP2,NXT2,TTBK2,PHLDB1,VPS13A,ROBO3,WSCD1,PSD3,TMOD1,BEX4" Drug 6272_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,PLA2G6,C1QTNF1,MRTFA,ASPH,SLC4A4,ATP2B2,SCAPER,BAIAP3,HOMER3,CSF1,FAM169A,CTH,CTNND2,HDAC4,DRD1,RCAN1,EIF4G2,NCALD,DLC1,FYB1,GALC,POLL,IL6ST,KCNF1,KCNQ3,MAP4,ADAM22,NCF2,NPPA,NPR2,OMG,EPN1,LRP12,POLG,PPP2R5C,WDR25,RGS4,TTLL7,KLHDC8A,SLC30A10,SLC15A2,ZCCHC24,PLCB1,ANKRD12,SEMA4A,KIAA0930,PCDHA3,TPM1,WIPF1,XRCC4,SPHK2,REEP1,SCG2" Drug 2765_UP Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ALCAM,BEGAIN,CDC42BPA,PPFIA3,ASPH,ALDH4A1,ST3GAL5,GYG2,BAIAP3,CFAP410,HAP1,STOML1,AKAP7,AKAP5,SH2B1,OSBPL3,RASSF2,DAPK1,SPOCK3,CDON,SLC12A6,EDIL3,EGFR,PDLIM5,ADAM28,GPM6B,TDRKH,CNTRL,HLF,HNMT,IGF1,ITPKB,NUMA1,CDK18,PDE1C,MAPK10,ZDHHC14,RGS3,RPS6KA2,ZNF821,RPH3A,PKNOX2,PDZD2,KAZN,SEMA4A,WSCD1,TCF7L2,ARHGEF12,DICER1,CHST8,CABIN1,SLC13A3,SEMA3B,SSPN" Drug 2883_DN Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ALCAM,AMPD2,EP400,BCAS1,CASK,NCOA1,ATM,MTMR9,MTMR2,CBR1,CCNT1,NMT2,NIPBL,HOMER3,RCHY1,SOCS5,DPYSL2,DTNA,CELSR3,ING4,HBS1L,INPP5K,INPP5B,MAP4,TM6SF1,MMP16,NRGN,PDE3B,PLXNB1,MAPK8,CNNM2,SIDT1,TMEM104,ELOVL2,PEX5,CEP97,RGS3,FBXW7,MCMBP,SFPQ,FBXO11,SYBU,EPN2,SPTAN1,SYNE2,SEMA4A,AGTPBP1,PCDHA6,TMOD1,MICAL1,REEP1,MPPE1,RNF170,SENP7" Drug 3966_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADORA1,ADORA3,APOC1,N4BP2L1,BAIAP3,CACNA2D1,CAMK2B,CBLN1,CD86,CDH18,CRLF1,WHRN,AKAP5,TCEAL2,GREB1,RIPOR2,HEPH,SV2A,TRAPPC9,FRY,TNK2,EPHB1,IGSF6,SPEG,ETV1,ANKMY1,FGFR1,DENND2A,ALDH1L1,GPM6A,STON1,GPER1,GUCY1A1,ICA1,KCNJ4,ADAM22,NEUROD1,KCNK10,SNTG1,PALM,PDGFRA,PTAFR,PTCH1,ZMAT4,RFX2,STUM,ACSBG1,ATP11A,SLC19A3,TMOD1,TRH,RUNDC3B,LAT2,ADAMTS9" Drug 2408_DN Disopyramide [3737-09-5]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "GRAMD1B,ALAD,ALK,ANK2,MAP4K3,APC,CDK10,RIPK1,SCAPER,CAMK2G,CAST,CDH10,SOCS6,ZFYVE9,KIAA0753,DPH1,FEM1B,SIDT2,COQ7,F3,F5,ZNF589,CAP2,SRCAP,ZNF276,SPACA9,VWA5A,MAP4,PFKFB2,MAPK8,ZSCAN32,RALGDS,ZNF493,RET,MYH14,TCP11L1,TMEM156,STUM,WDTC1,DDN,TROVE2,MAPK8IP3,FAM168A,EXOC7,IQCE,TCF7,TK2,PIK3R5,RBFOX2,TPM2,UBTF,XRCC4,PRDM2,GDPD5" Drug 3675_UP Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "SLC12A5,AP2A2,NME5,OGT,N4BP2L1,CACNA1I,USP2,RGN,CHRNB2,MYRIP,RIMS2,SEC14L5,RIPOR2,EDN1,KCNMB2,CAMSAP1,SEMA4D,GNAL,GPM6A,LPAR4,ITGA7,KCNJ4,ADAM11,TAGLN3,OMG,CDK18,PDE2A,PDE4B,POU3F4,MED1,ZSCAN32,PTPRO,NKAIN1,RFX2,SH3BP2,NTNG1,SLC6A11,ARHGEF40,CXXC4,IGSF9B,SNCA,UNC5B,LMO3,ATP10B,MLC1,SYN2,ASTN2,EXOC7,PIK3R5,TPM3,MICAL1,LAT2,ZNF154,SENP7" Drug 3271_UP Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ACTN2,ADORA2A,AGT,KIAA1324,APBB2,PPP4R4,CDK13,DNAH17,ASPH,SLC2A11,CDK5R2,LDLRAD4,CACNA2D1,CNTFR,CRMP1,HP1BP3,TMCC2,DSCAM,DTNA,CNNM1,MBNL2,SORBS3,SCML2,FGF12,FYB1,GLYR1,STON1,GPER1,HPSE2,ITPKA,KCNN2,KCNQ3,MAN2A2,ADAM11,NF1,NOVA2,NUMA1,PDE3B,CDK14,SMOX,ZCWPW1,KCTD17,TRA2B,RBM34,VAMP1,ARC,SYN2,PCDHGA10,ZNF34,CA14,VLDLR,WIPF1,ZNF74,ITM2C" Drug 2906_DN Meptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,KCNAB2,RIPK1,ADAM15,BCL7A,SLC16A4,SCARB1,CNOT8,RAB28,CLCN3,NIPBL,TM9SF4,HP1BP3,C2CD2L,HIPK3,FCF1,VPS26C,ZNF589,GLS,GPR22,IDH3A,IPO5,SMAD1,MAP4,N6AMT1,NEFH,NUMA1,PIK3R1,CCSER2,DEF8,TMEM231,SUPT20H,HSPA4L,KBTBD4,TMCC1,KDM4B,THSD1,STX1A,MLC1,EXOC7,PDLIM2,TCF4,PSD3,AP4E1,PARD3,TRPS1,HIRA,ZNF32,TFIP11,NT5M,GDPD5,HPS4,PHTF2,NLRP3" Drug 2251_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NME5,PLA2G6,APBB2,GAS7,PPP4R4,DNAH17,ALDH4A1,ATM,SLC4A4,CFLAR,CA4,CACNA2D2,SOCS6,ZFYVE9,CNTN1,GREB1,SMG7,DPH1,DTNA,EFNB3,PLXNC1,CDKL3,RRAGB,ACSL4,SRCAP,RAB30,GNAS,GSN,ELOVL5,IL6ST,KCNH2,LMO2,VWA5A,MMP16,ADAM22,ZNF862,NF1,NPR2,CDK18,PPP2R2B,RAB3A,TCP11L1,MAPK12,WDTC1,UNC5B,TROVE2,THSD1,SEMA4A,KIAA1107,SLC44A1,CABIN1,ZIC3,REEP1,MAP3K12" Drug 3541_UP Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASIC1,SLC12A5,AGT,C1QTNF3,SYT13,CACNA1I,CACNB2,HAP1,CAMK2B,LDB2,ARHGEF2,ARHGAP33,CHRNB2,AKAP7,ENTPD4,RASSF2,C2CD2L,SIDT2,HSD17B14,RASGRP2,MALT1,GLYR1,GNAS,RASSF8,PTGDR2,ICA1,IL6ST,KCNA2,KCND3,BCO1,NOVA2,P2RY1,PLCD1,PLTP,PACSIN1,FAM184A,RGS12,SELL,ZNF821,PPP1R9A,SYBU,KANSL3,SLC6A8,SMARCD3,ZCCHC24,TROVE2,MAPK8IP3,ACSBG1,TNS2,CRTC1,HIF3A,TRPC1,WIPF1,GDPD5" Drug 5995_UP Epirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,LTBP4,KCNAB2,GAS7,MARK4,CACNG1,HAP1,CAMK2B,USP2,RCBTB2,MYRIP,NCOR2,CSF1,NOS1AP,DBT,GSDME,HIPK3,COQ7,FGFR1,CAMSAP1,OGA,ZMYND11,INPP5K,ATF7,GRIK5,NR3C1,KLF12,TJAP1,KCNH2,KCNMA1,ADAM22,MYH7,NOVA2,CDIP1,PROX1,ZSCAN2,C1orf54,FAM184A,ZDHHC14,WLS,SCN3A,ASAP3,SMARCD3,KIF13A,WDTC1,PHLDB1,PCDHGA1,TEX15,CRB1,METTL3,TRPC3,VAV2,MICAL1,CLIP2" Drug 4316_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "MRTFA,CDK10,ARNTL,SLC4A4,FOXN3,CNOT8,TAOK2,HOMER3,VCAN,PDE4DIP,MFAP3L,SRGAP3,KBTBD11,EDIL3,ING4,VPS26C,FGF1,PDLIM5,FAM49B,OGA,HTATSF1,POLL,GNG4,IL6ST,ODF2,LRP12,WDR25,PTN,C1orf54,TTLL7,TCP11L1,SFPQ,FBXO11,PPP4R3A,DOP1A,SPTB,SYT1,SMG6,ZEB1,CHST8,TRIO,ZMYND8,RPRM,VIPR2,ZNF711,ZNF74,TFIP11,ZNF225,EMSY,PRDM2,EVI5,VPS35L,KCNAB1,PHTF2" Drug 5423_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ARID1A,ADCY2,AP2A2,PLA2G6,CDC42BPA,GAS7,CAMK2G,CBFA2T2,ZFYVE9,QKI,RCHY1,TCEAL2,OSBPL3,PLCH2,ARHGEF4,RASSF2,RIMS3,DTNA,HIPK3,MRNIP,FECH,FHL1,AFF2,ADAM28,GRM1,GRM7,AP4S1,TJAP1,MMP17,MOBP,NEUROD1,NNAT,PDE1C,PDE3B,PFKFB2,TNPO2,LRRN3,MYH14,RPS20,SCN8A,SH3BP2,DOCK10,ARHGEF40,ZHX3,UNC5B,NPAS3,SAMSN1,MAPK8IP3,DOCK9,R3HDM1,FLRT2,NT5M,DNALI1,DPF3" Drug 7246_UP Etodolac [41340-25-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "APC,CDK5R1,NRXN3,PLAA,HOMER3,ARMC8,CREM,SH2B1,NCOR1,CTNND2,LYPD1,SMG7,CDON,EDIL3,TUBD1,PLEKHO1,ABCA8,ACSL4,FGFR1,TRMO,ERAP1,GLRB,HTATSF1,BTN2A1,SYNPO,IRF8,KIF5C,TAGLN3,NF1,NRCAM,NUMA1,PFKFB2,MAPK7,WDR25,PTPN13,ARID4A,RGS4,MAPK12,PPP1R9A,WDR37,PPP4R3A,SLC20A2,SS18,ELOVL4,SMG6,SZT2,CRTC1,ZNF34,TK2,R3HDM1,ZMYND8,UGT8,KCNK12,ST7" Drug 169_UP FK-506; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASIC1,SEMA7A,APBB2,PPFIA3,PDXK,RASL11B,MPDZ,BMP7,CA4,TBRG4,SDC3,ARHGAP32,C2CD2L,DRP2,RCAN1,OPTN,TUBD1,ERBB2,PTK2B,GART,NEU3,SRCAP,RUNDC3A,PSIP1,KLF12,ACOT7,AGBL5,KCNA1,KCNN1,MBD1,NELL2,RETREG1,SMOX,PMP22,CEP41,MAPK3,CYBC1,TMEM104,NKAIN1,RGS3,TCP11L1,FNDC3A,EPN2,KBTBD4,SLC15A2,ZKSCAN3,SMARCD3,CDK19,SPART,CLASP2,CEP68,HEY1,CA14,WIPF1" Drug 4840_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADRA1D,AMPH,APBA2,APC,PDE8B,MTMR3,CACNA1G,BAIAP3,CACNB2,CDH8,CDH18,CLGN,TMEM59L,PICK1,NRG2,CRMP1,HAPLN1,RIMS2,DBN1,MFAP3L,MAGI2,EFNA3,EGFR,C3orf18,DCTN2,HBS1L,GAP43,DISC1,GNAO1,GPR22,GRB10,C2orf72,KCNJ4,KCNMA1,LMO2,LSS,NNAT,SERPINI1,PIK3CD,PMP2,POU6F1,PPP2R2B,ZSCAN2,ENOX1,ASIC4,FRMPD1,CNKSR2,SNCA,WDTC1,PEG10,NXT2,ACSBG1,DAAM2,SSPN" Drug 2862_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "NDRG2,BRAP,ATP6V0A1,CFLAR,CAMK2G,KRIT1,CBFA2T2,SCARB1,RCBTB2,ZFYVE9,HOMER3,NECTIN3,CSNK1E,PDE4DIP,GREB1,KBTBD11,EDNRA,CELSR3,MBNL2,SORBS3,DMTN,FGFR1,FAM49B,DISC1,SRCAP,POLL,HNMT,INPP5B,KHK,MAP4,NUMA1,PDE3B,PPP5C,PRKAB2,PLPPR1,FAM184A,RGS3,CARF,CLIP1,TRAPPC13,SH3BP2,SYBU,WDTC1,GLT8D1,ELOVL4,ATP11A,TCF7L2,TNS2,CRTC1,AP4E1,TK2,UBE3A,PLPPR2,LMF1" Drug 5867_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "SLC12A5,C1QTNF1,SEMA6A,APAF1,AZGP1,NRP2,BMP7,GYG2,CHRNB2,NRXN3,QKI,RAB26,CNTFR,SLC4A8,CSF1R,TRAPPC9,TOM1,HSD17B14,VPS26C,EXTL1,REEP2,FOXG1,SORBS1,ERGIC3,GFER,GNAL,ADAMTS8,HPCA,KCNN1,KHK,KIF5C,KPNA5,MAPT,AFDN,MOBP,MYCN,CNOT4,SLC11A2,NTRK2,ENPP2,GPR85,SAMD9,PEX5,RORB,NEK11,ASAP3,SLC4A3,TMCC1,PDZRN3,RBM34,CEP68,COBL,TK2,LMF1" Drug 3985_UP Troleandomycin [2751-09-9]; Up 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ABAT,PLA2G6,ATP2B2,CADM3,CALB2,ARHGAP33,NRXN3,LY86,CNTFR,AKAP5,DPP6,DSCAM,DYRK1A,EDIL3,HIPK3,CELSR3,EPHA5,FABP7,GAP43,ATP8A2,ADAM28,CSDC2,GPR17,GRIK2,SPACA9,ADAMTS8,C2orf72,IGFBP1,IL12A,KCNF1,MDFI,MMP16,MOBP,MYBPC1,CNOT4,NTRK3,PDGFRA,PENK,PLCD1,CEP41,WDR25,RGS4,MRAS,KANSL3,ZNF334,DOK5,ARHGAP26,PHLDB1,ARC,TBCEL,SLC44A1,HIRA,VIPR2,NLRP3" Drug 3287_UP Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "TKTL1,ADCYAP1R1,ALCAM,CDC42BPA,PTCH2,CACNA1I,FOXN3,RAB33A,NCOR2,CSF1,CSF1R,DCAF8,CTIF,BRINP1,MED12,ATP8A2,ALDH1L1,POLL,STON1,GPER1,GRIK5,NR3C1,PTGDR2,ATXN2L,SMAD1,MMP17,ADAM22,MX1,NPTX2,PIK3CD,MINDY2,PRKCB,ZMAT4,RGS12,ASAP3,ABLIM3,SLC1A7,KIF13A,WDTC1,ZC3H13,ARHGAP26,VAMP1,SYN2,ATP11A,TRIM2,SZT2,DOCK9,PCDHA6,HEY1,HEY2,TNS1,SPHK2,SLC30A3,PLSCR4" Drug 2289_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,ADORA2A,AP2A2,ALCAM,APAF1,APLP1,AQP4,ADAM23,SYNJ2,MTMR3,CACNA1G,USP2,NEURL1,CLCN4,CLTB,DNAJB5,SDC3,DAPK3,DTNB,SGK2,ING4,PIPOX,ZNF44,RND1,GPER1,GRIK5,KLF12,IGF1,IL11RA,KCNJ5,MAOB,MATN3,MID1,NDUFA5,NNAT,OPCML,GPR85,PFKFB2,C19orf57,PRKAR1B,PTPRB,RPS6KA2,ASAP3,SLC1A2,BTBD7,LIMCH1,ATP10B,VAMP1,DMXL2,PCDHGA10,CRTC1,PRDM2,MVB12B,DPF3" Drug 3360_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADRA1D,ALK,AMPD3,SEMA7A,CDC14B,ARRB1,DNAH17,MTMR9,CBFA2T2,CDH10,SLIT2,SULT4A1,HOMER3,CNTN1,WHRN,PHF14,CTH,RIMS3,SPOCK2,DMPK,ATN1,HIPK3,FGFR1,GAD2,TMEM8B,SEPT9,GCNT2,SRCAP,GLS,ATF7,ITIH2,KCNJ5,KCNN2,SMAD1,MMP16,GPR85,PURG,FSD1,PRKAR1B,MAPK7,PTAFR,RGS10,SYNDIG1,PREX2,SAMSN1,ARC,PCDHGA10,PSD3,TNS1,KLC2,XRCC4,ZIC3,KCNAB1,JPH3" Drug 6892_UP NS-398; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADD2,PLA2G6,LTBP4,CDK13,DNAH17,BACH1,BMP7,IL33,HAP1,CACNA2D2,PICK1,AKAP7,CPS1,SH2B1,CREB5,CSF1,MFAP3L,SGSM2,RABGAP1L,DRD1,SGK2,FEM1B,AASS,DCTN2,PRELID3A,CSPG5,GAB1,MSL3,ICA1,TJAP1,KCNN1,LAMA2,MAP2,MGAT3,MN1,MSI1,MX1,MYO6,NASP,NFYA,NOS1,OPRL1,PDE4D,PFKFB2,PTCH1,PTHLH,RPS6KA2,TRAPPC13,KIAA1107,TRIO,RPRM,UGT8,LAT2,RNF170" Drug 5815_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ARID1A,ANK1,APBB2,DDO,ALDH4A1,KIF1A,CDC42,ASIC3,CNOT8,NRXN3,IQCK,AATK,DCAF8,CNIH3,DMD,DUSP9,MBNL2,IRAK4,EPB41L1,IGSF6,TBC1D16,ZNF589,TRMO,GAD2,SYT17,GLI2,LPAR4,GPER1,MAPT,ADAM22,TAGLN3,LYRM9,ZNF862,NF1,TNPO2,PPP5C,RGS12,NEK11,ITSN1,FNDC3A,PKNOX2,KDM4D,MYH15,SNCA,TNIK,CEP68,MCF2L,KCTD2,TNS1,TPD52,RPRM,WIPF1,EVI5,MPPE1" Drug 6508_DN Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ADRA1D,MTUS1,TRMT9B,CDC14B,PDE8B,ALDH4A1,CFLAR,SGCE,CDH10,MAGI1,CACNA2D2,NRG2,NCOR1,PDE4DIP,DZIP3,EDRF1,ARHGAP24,DCAF8,JAKMIP2,RABGAP1L,DNM2,EGFR,COQ7,MTSS1L,VPS26C,C1orf61,ZMYND11,GNG3,HSF2,INPP5B,MAPT,GIT1,LYRM9,NNAT,PIK3CD,PLEC,PRKAR1B,MAPK8,PTN,RAB3IL1,ZDHHC14,ZC3H14,SLC6A8,SHANK2,CXXC4,CDK19,MAPK8IP3,ASTN2,PSD3,TK2,KCNK12,ZNF45,EMSY,URM1" Drug 7222_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASPHD1,SEMA4G,MARK4,ST3GAL5,CACNA1D,SLIT2,VAX2,DNAJB5,WHRN,HAPLN1,CSF1,ARHGEF10,SDC3,RIMS2,JAKMIP2,EFNA3,EFNB3,PHF20L1,FGFR3,FLNC,GALC,GART,POLL,GRM1,ELOVL5,HNMT,KCND3,KCNH2,LIG4,KITLG,MITF,NCAM1,NFYA,NNAT,NUCB1,EPN1,PRODH,PTHLH,ZSCAN32,RAB3A,RGS12,SH3BP2,CNKSR2,SYBU,EPN2,WDTC1,IQSEC2,ATP10B,EXOC7,SYNE1,OBSL1,PCDHA6,ZNF24,ZNF74" Drug 574_UP tetraethylenepentamine pentahydrochloride; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "GRAMD1B,APAF1,APOC1,ASCL1,CADM3,BAIAP3,HAP1,ARHGAP33,DLGAP1,CHRNB2,DCC,RCAN1,EDNRA,EFNB3,EGFR,CALCRL,STX2,PTK2B,KIAA1109,NSG1,PCDH17,GNAO1,NR3C1,IRF8,IGF1,IL6R,MARK1,MID1,NPR2,P2RY1,SNTG1,PDE1C,LRRN3,MAPK3,PYGM,C1orf54,RNASE1,TCP11L1,SYNDIG1,RXRG,ATXN2,SH3BP2,PREX2,SCN3B,CLASP2,TCF7,PHF24,SLC35G2,ZMAT3,ZKSCAN5,AMOT,CLIP2,STMN4,SLC17A7" Drug 2367_UP Vincamine [1617-90-9]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "MRTFA,BIN1,MARK4,CAPRIN2,CCDC181,AZGP1,BACH1,MTMR3,CAMK2G,SEPT7,CLCN4,FAM149A,CRY2,SIPA1L1,VCAN,PDE4DIP,SLITRK5,DBN1,DLG3,TRAPPC9,RCAN1,EEF1A2,COQ7,DLC1,FGFR1,GPR12,GRIN1,ELOVL5,KCNMA1,GIT1,ZNF862,NF1,PLCB2,TMEM231,RAD52,SCN2B,ZCCHC24,KDM4C,PEG10,SEPT8,TACR1,CAMSAP2,SIN3B,PHF24,ATP13A2,TK2,TMOD1,TNS1,RBFOX2,TRO,TUBB1,PLPPR2,SYNC,PCBP4" Drug 5068_UP Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 54 199 "ASIC1,ACTN2,NDRG2,ALK,NRP2,CFLAR,CACNA1I,BTRC,RUNX1T1,ENTPD2,ZFYVE9,ARHGEF10,DUSP9,COQ7,MTSS1L,SPEG,FGFR1,FYB1,PCDH17,PTGDR2,ATXN2L,KLF12,KCNJ3,KCNJ5,KIT,LIFR,LSS,MATN3,LYRM9,NPR2,NTRK2,PHKG1,PRKAR1B,GRAMD1C,PROX1,PTPRN2,RGS10,FBXW7,EMID1,NCBP3,DOCK10,SLA,SLC12A4,SNCA,ZHX3,SPTB,ZBTB43,DDN,PHLDB1,COBL,KIAA1107,TCF4,SLC44A1,KCNAB1" Drug 4541_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.60E-05 1.00E+00 3.53E-04 4.02E-03 50 180 "ARID1A,GRAMD1B,BCAR3,MAP4K3,APC,ARHGEF7,SOCS6,ZBED5,NIPBL,NECTIN3,PUM1,DYRK1A,FAM13A,WAC,SEC24B,CAMSAP1,TACC2,GBX2,DIDO1,NR3C1,KIF2A,MARK3,MEF2C,NFE2L2,NFYA,CNOT4,PFKFB3,STRN3,PPM1B,SETD5,SCAF8,CHD9,SYBU,WDR47,JMJD6,ZC3H4,ANKRD12,MTCL1,TCF7L2,ZEB1,PUM2,KAT6B,ZMYND8,PITPNB,ZNF45,ZNF189,PRDM2,NAV2,KAT6A,JMJD1C" Drug 3637_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.60E-05 1.00E+00 3.53E-04 4.02E-03 50 180 "BIN1,APBA2,APOC1,CDK13,ASCL1,CACNA2D1,USP2,ARHGEF2,CDO1,CLGN,CHN2,CLCN4,ABI3BP,TRAPPC9,DPP6,DTNA,DYRK1A,ENO2,ERCC2,PTK2B,KIAA1109,AMOTL2,FOXG1,OGA,GFER,GRB10,MIA2,CDK18,PIK3CD,RAD52,C1orf54,ZNF821,PPM1E,PKNOX2,SLC6A9,PDZD2,SOX10,KDM3A,UNC5B,NPAS3,COLGALT2,SYN2,HIF3A,TEX15,CHST5,RUNDC3B,VLDLR,LAT2,KCNAB1,PAK5" Drug ctd:D004026 Dieldrin CTD 2.62E-05 1.00E+00 3.56E-04 4.05E-03 244 1221 "SERPINA3,ACLY,ACTN1,AXIN2,CDC7,FZD9,ADRB2,MTA3,AGT,TXNDC16,ALK,MRTFA,BIN1,ANK1,APAF1,APBB1,APBB2,APLP1,VAT1L,API5,APP,MIER1,CDK10,ARRB2,CDK13,PTCH2,BRINP2,ATM,ATP2A2,ALDH7A1,FGF17,BID,LDHD,DST,GYG2,CAMK2A,CAMK2B,CAMK2G,CAPN3,PRC1,KYAT1,CCKBR,CERS5,CCNH,CCNT1,SLC16A4,AIFM1,SCARB1,DGKI,LRBA,SEPT7,CDC25B,CDH2,DCLK1,LGI1,CCPG1,FOXN3,CHGB,CHRM1,CHRM4,CHRNA4,PPT2,COG1,ABCG2,ARHGEF6,CNRIP1,CRHBP,LRRC3B,CSNK1E,SIPA1L1,ERC2,BOC,TOMM20,BRINP1,DNAL1,ALKBH8,PARD6A,TRAPPC9,CASP8AP2,FIS1,E2F5,ST8SIA3,FEM1B,EGFR,ASB3,EIF4G1,PLEKHA1,TUBD1,STX2,ACSL4,TESK2,KIAA1109,FGF1,FGF12,FGFR1,PCYOX1,FOXO3,DCTN2,POMT1,USP16,ARFGAP2,MPP6,FYN,GABRA1,GABRA2,GABRB3,GABRG1,GABRG2,GAD2,GAP43,MSTN,SESN1,GFAP,NFU1,GFER,MMADHC,GFRA1,GPM6B,GPR17,GRIA1,GRIA2,GRID1,GRIK3,GRIN1,GRIN2C,ATE1,GRM5,CIT,FICD,IRAK3,HBA1,HTR5A,IDH3B,IGF1,SCIN,LRRTM3,CREG2,KIT,SFXN5,LMO1,SYTL4,VWA5A,NAT8L,MAPT,AQP11,MBP,TM6SF1,MDM4,AFF1,COMMD5,MYCN,NAP1L1,NASP,NEFM,NEFH,SLCO1C1,NPY,NPTX1,NTRK2,NTRK3,OPA1,P2RX7,PC,PDCD2,PDGFRA,PENK,CDK14,ABCB1,PMP22,POLR2F,MAPK3,MAPK10,SLC26A11,SLC22A23,APTX,PTN,PTPRO,PYGM,NKAIN1,RET,GTDC1,KIF7,ELP2,ZC3H14,RXRA,TRAPPC13,SALL1,MAPK12,HOGA1,SCN2A,SMPD3,SOX6,FOXRED1,SGK1,ST6GAL1,SLC6A8,SIRT2,CDK5RAP3,SLC12A4,ABTB1,SMARCA4,SNAP25,SNCA,FAIM2,LMBRD1,RBM34,KDM4B,SON,UNC5B,ERBIN,STXBP1,JMJD6,ABCC8,PLCB1,TAC1,VWC2,TCF7,ZMAT3,SLC44A1,TJP1,CDK20,PDSS1,TRPC1,TSC1,TSC2,TTPA,BCL2L13,MTCH1,VIPR2,BEST1,NSD2,WNT7A,SLC13A3,SF1,SLC26A10,ZBTB16,POLR3H,MFF,SLC38A1,RGMA,FZD3,RTN4,NUP214,FXR1" Drug CID000004485 nifedipine Stitch 2.64E-05 1.00E+00 3.58E-04 4.08E-03 97 415 "SLC12A5,ADRA1D,ADRA1B,ADRB2,AGT,MYH7B,APP,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CH25H,KRIT1,LRBA,CACNA2D2,CHRM1,MYL6B,FADS2,DBI,HEPH,DMPK,CALN1,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EIF4G2,CACNG3,CACNG2,PTK2B,ATP2C1,CYP46A1,GGT7,GGT5,KCNMB4,GPT2,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,HTR2A,MYLK2,KCNA2,KCNMA1,BCO1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,NPY,NPPA,SLC11A2,ABCB1,PKD1,SEPT4,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,QDPR,MYH14,RYR1,RYR3,MYO18A,TAC1,TACR1,TPCN2,TF,CABIN1,TRH,TRPC1,NLRP3" Drug CID000164810 kainite Stitch 2.71E-05 1.00E+00 3.68E-04 4.18E-03 16 35 "STX2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,NOS1,MAPK10,MAP3K12" Drug 2686_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.71E-05 1.00E+00 3.68E-04 4.19E-03 51 185 "ASPH,CACNB4,CDH10,ARHGAP33,CRLF1,CLU,BAG4,CREM,CRYBB1,SIPA1L1,PDE4DIP,CTNND1,USP6NL,SRGAP3,ST8SIA3,FAM13A,MBNL2,AASS,SORBS3,C1orf61,CAP2,FYB1,GNG3,GSN,HNMT,KCND3,KCNH1,MMP16,ADAM22,NEFM,PDE4B,MTRF1L,SEPT4,MBOAT7,PRKACB,PTHLH,SUGCT,HSPA4L,SLC15A2,ZNF415,FAM168A,AP4E1,TGFBR3,TIAM1,TK2,RIMBP2,FAM155A,KCNK12,ZBTB38,ZNF225,PAK5" Drug 1673_DN Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.71E-05 1.00E+00 3.68E-04 4.19E-03 51 185 "CDC42BPA,BCL7A,CFLAR,CCNT1,CDC27,SLC4A7,TBC1D5,HP1BP3,NR1D2,FCF1,PCYOX1,CRCP,SPIN1,KIF3A,KIF5C,MAP4,MIA2,MITF,MMP16,MYO6,NPR2,PIK3R1,RC3H2,TNPO2,MED1,PKN2,TMEM260,PLEKHB2,SLC25A36,SEC14L1,SON,ERC1,ZBTB43,SRPK2,CEP68,PRRC2C,ANKRD12,TBL1X,EHBP1,DICER1,TMPO,KAT6B,CADM1,ZNF24,ZBTB38,WNK1,PRDM2,SLC38A1,SNX27,MPPE1,FXR1" Drug CID003064778 HA1 100 Stitch 2.74E-05 1.00E+00 3.71E-04 4.22E-03 30 90 "TKTL1,KLRC4,CDC42BPA,NOG,CRLF1,PARD6A,EEF1A2,GAD1,GAP43,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MSI1,NOS1,NRGN,OPRL1,SALL1,JMJD6,SYN1,ARC,SYN2,WWC1" Drug ctd:C502851 quinocetone CTD 2.77E-05 1.00E+00 3.76E-04 4.27E-03 64 248 "GALNT13,NR0B1,TXNDC16,BIN1,DPP10,SEMA7A,SLC7A14,ARHGDIA,ASPA,FUBP1,CA4,CACNA2D1,CALB1,CCK,DCLK1,CFL2,FADS2,ABCG1,PLCH2,VCAN,RIMS3,CDON,ECM2,EDNRA,ENO2,CDHR1,ADGRV1,ST6GALNAC3,MEGF10,PCLO,GRM8,HMGCR,INSM1,LAMA2,STMN1,LSS,AQP11,MATN3,NDP,NFE2L2,PDE2A,PFKP,PLP1,SDK2,RELN,ENOX1,LRRK2,RYR3,SCN2B,RASA3,PPP1R9A,FHOD3,PDZD2,SPP1,ZNF423,ARHGAP26,NFASC,STAC2,SULF2,TAC1,ADGRL3,ACSL6,WNK2,PAK5" Drug CID000003894 lavendustin A Stitch 2.78E-05 1.00E+00 3.77E-04 4.29E-03 48 171 "CNTNAP1,APBB1,APBB2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,LRBA,CACNA2D2,CNGA3,CACNG7,EGFR,ERBB4,CACNG2,FOXM1,FYN,GLRB,GRM5,HRH3,TLX1,IGF1,JAK2,KCNH2,KCNMA1,MATK,NTRK3,PIK3C2A,PIK3CD,PIK3R1,PKD1,PRKACB,PRKCB,PRKCG,RASGRF1,RYR1,RYR3,SLA,STAU1,SYN2,PIK3R5,GORASP1,MFF" Drug 5247_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.78E-05 1.00E+00 3.77E-04 4.29E-03 48 171 "NDRG2,SEMA6A,SRPX,APAF1,APBB2,APOC1,PDXK,ARHGDIG,GYG2,CA12,CANX,LRRFIP1,B4GALT6,QKI,ENTPD4,RIMS3,SACS,G3BP2,ING4,RACK1,CAMSAP1,RAB40B,KCNJ3,MIA2,KITLG,MMP16,NPTX1,NRCAM,PCDH9,PDCD2,PMP22,MBOAT7,PPP2R2B,RAB3IL1,TCP11L1,BTBD7,CDK19,TROVE2,KIAA0930,PCDHA6,ZMAT3,CBX5,METTL3,REEP1,SLC38A1,PHTF2,NETO2,GAN" Drug CID000038022 CCD 1042 Stitch 2.80E-05 1.00E+00 3.80E-04 4.32E-03 13 25 "ABAT,CHN1,SV2A,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,KCNQ2,KCNQ3,SLC6A1" Drug CID004188587 methanethiosulfonate Stitch 2.80E-05 1.00E+00 3.80E-04 4.32E-03 33 103 "ADRB2,ASIC3,GDA,DTNB,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GLRB,GRIA1,GRIK1,GRIN2C,KCNA4,KCNC1,KCND1,KCND2,KCND3,KCNH2,KCNJ3,KCNJ4,KCNJ5,HCN1,ABCB1,RNASE1,SCN4B,SLC1A2,SLC1A3,SLC6A1,SCN3B,TPM3,ST8SIA2" Drug 7301_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "ABHD6,ADCY6,KIDINS220,CDC42BPA,KCNAB2,CDC14B,CDK10,SEMA4G,MAP7,RAB26,OSBPL3,ARHGEF4,CTNND2,CTIF,DNAJC6,SPOCK3,DTNA,MTSS1L,FOXG1,FLT1,SORBS1,FYB1,GAB1,SYT17,COPS8,GNG4,GRK4,SPACA9,KCNMA1,MAPT,MIA2,NFYA,GPR85,FA2H,PRPH,WDR25,PEX5,TMEM231,RGS4,KCNIP1,IL17RB,SH3BP2,SLC11A1,TMCC1,UNC5B,KAZN,SLC35G2,TIAM1,CHST5,ZMYND8,ZNF711,PARP6" Drug 5237_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "AK2,APC,ARRB1,PDE8B,ASPH,BRINP2,ATM,STX16,CFLAR,CACNA1I,CAMK2G,SPAG9,SCARB1,SLC4A8,DTNA,YAF2,SUGP2,ANKFY1,PDLIM5,FAM49B,OGA,ZMYND11,GFER,GNG4,STON1,KCNJ3,CNOT4,NPR2,NRCAM,LRP12,PMS2,PRODH,SYTL2,RAB3IL1,ROM1,ZNF430,SLC15A2,MAPKBP1,SNCA,TROVE2,POGZ,NXT2,DIP2A,DICER1,TMPO,ZMYND8,VIPR2,WNK1,HPS4,SEMA3B,PHTF2,SENP7" Drug 5786_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "ASIC1,ADORA3,TRMT9B,APAF1,PRX,CACNA1I,BTRC,INA,LARGE1,IFFO1,AKAP12,HDAC9,EDIL3,EGFR,EXTL1,EZH1,F5,SORBS1,GFER,GRM7,GSTM5,PADI2,SHISAL1,KCND2,KCNH2,KCNJ5,NOVA1,NPPA,OPRL1,LRRN3,VPS13C,PTX3,NKAIN1,KHDRBS2,RGS4,RGS7,KCTD17,SYNDIG1,PKNOX2,SLC12A4,ZC3H13,RBM26,ARC,TCF4,DOCK9,ICAM5,TMOD1,RUNDC3B,RPRM,XRCC4,NAV3,PARP11" Drug 4322_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "MRTFA,ANK3,PKP4,PDE8B,ASPH,SRSF11,CRMP1,CNTNAP2,SPOCK2,SMG7,CHRDL1,ATN1,EDIL3,FCF1,MBNL2,ING4,EPB41L1,C1orf61,PDLIM5,CRCP,GNG3,GPD2,SPACA9,RASSF8,AGFG1,IFI16,IL6ST,KIF5C,VWA5A,MAP4,CNOT4,NUMA1,STRN3,LRP12,MINDY2,PRKAB2,RAD52,C1orf54,RGS10,KIRREL1,SLC1A7,PPP4R3A,TIAM1,TMPO,OSBP2,SF1,WNK1,PRDM2,EVI5,KCNAB1,KAT6A,PHTF2" Drug 1400_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "ADD3,ARNTL,MARK4,ST3GAL5,SCAPER,WASF1,HIP1R,CBFA2T2,LRBA,FEZ1,PPP1R16B,CX3CR1,ZFYVE16,ZNF337,C2CD2L,GSDME,ANKRD46,FAM13A,MRNIP,EPB41L2,EXTL2,FGFR1,PDLIM5,ATP2C1,RUNDC3A,IFI16,KIF5C,MAP4,MEF2C,PCDH9,SERPINI1,CCSER2,RETREG1,GPSM2,PLCD1,MINDY2,PPM1B,PRKACB,PTX3,C1orf54,PAQR6,SATB1,ATXN2,FAM102A,CCDC88A,ZSWIM8,RGL1,STXBP1,TCF7L2,ARHGEF12,CBX5,TRIM9" Drug 5942_UP LY294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.82E-05 1.00E+00 3.82E-04 4.34E-03 52 190 "AP2A2,AGT,APOC1,APP,CDK13,CAMK2B,MAP7,REPS2,SLC4A7,CPS1,AKAP12,LPAR6,EZH1,TESK2,GABRA2,ERAP1,GART,SESN1,GLS,KCNMB4,TDRKH,STON1,SPACA9,ICA1,ITGA7,ZNF862,NF1,NUMA1,PDE4D,SERPINI1,PIK3R1,CNNM2,CCDC40,RALGDS,TTLL7,TCP11L1,RPS6KA2,ATXN1,IL17RB,ZNF667,SNCA,IQSEC2,TROVE2,MAPK8IP3,CEP68,VAMP1,ARHGEF12,TK2,TRIO,VIPR2,PLSCR4,TIGD6" Drug CID000435143 NSC-364372 Stitch 2.87E-05 1.00E+00 3.88E-04 4.42E-03 110 484 "APBA2,APC,CDK10,NCOA1,ATP6V1G2,HCN2,BID,CFLAR,KSR1,CCNT1,CDC25B,CDC42,LGI1,NUMBL,EPS15L1,CLTC,TJP2,QKI,RCHY1,CREM,SH2B1,CRY2,CSNK1E,CSNK1G3,CTNND1,HDAC9,HDAC4,HP1BP3,ARNT2,MED12,DYNC1I1,DNM2,ABI1,DUSP9,E2F5,TMTC1,ABI2,APC2,PPP1R1B,UBE2E3,FOXG1,FOXO3,DCTN2,KHDRBS3,FYN,NCKAP1,GCK,MALT1,ZNF276,TCERG1,COPS8,CBX1,GRB10,NR3C1,PACSIN2,DDX19B,SYNPO,HMX1,HNRNPK,HSP90AA1,IGF1,ITPKB,JAK1,KPNA5,IPO5,LIMS1,MXI1,NACA,BEX5,NFE2L2,NRDC,PBX1,PENK,EPN1,PACSIN1,TNPO2,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTH1R,KHDRBS2,GSTCD,FBXW7,RXRA,MAPK12,FOXRED1,EPN2,PKNOX2,SIRT2,SNRPN,PALLD,SOX10,HECW1,KANK1,SYT1,SIRT1,THRA,SYNPO2,NEIL2,UBC,EIF4ENIF1,XPO1,ZBTB16,TUBA1A,NUP214,FXR1,JPH3" Drug CID000001775 phenytoin Stitch 2.89E-05 1.00E+00 3.91E-04 4.45E-03 58 219 "ABAT,ASIC1,ACHE,ARSE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,ASIC3,QKI,BOC,DPH1,CACNG7,DMTN,CACNG3,CACNG2,FOXF2,CELF1,CYP46A1,POLL,NR3C1,ATCAY,KCNA1,KCNA2,KCNH2,MAP2,MEST,NOS1,NOVA2,ABCB1,PKD1,MAPK3,PTCH1,PTHLH,PTN,LGI2,RYR1,RYR3,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,LGI3,SCN3B,TPCN2,FLRT2,LGI4,DPYSL5" Drug CID000001065 quindine Stitch 2.89E-05 1.00E+00 3.91E-04 4.45E-03 58 219 "ASIC1,ADRA1B,AGT,ATP2A2,HCN2,CACNA2D1,CACNB2,ASIC3,CHRM1,CHRNA4,CHRNB2,CLCN3,ABCG2,SULT4A1,BOC,DBI,DMPK,SLC29A4,DMTN,KCNMB2,CELF1,KCNMB4,GYG1,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,KCND1,KCND2,KCND3,KCNH1,KCNH2,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN3,MYL3,KCNK10,ENPP2,ABCB1,AP1AR,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SHANK2,SLC14A1,SLCO1A2,SLC22A4,SCN3B,DPYSL5,HPS4" Drug CID000014241 ethylglutamate Stitch 2.92E-05 1.00E+00 3.92E-04 4.45E-03 10 16 "GAD1,GAD2,POLL,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug CID005487475 Gr-94800 Stitch 2.92E-05 1.00E+00 3.92E-04 4.45E-03 10 16 "BOC,B3GAT1,CRCP,GRIK1,KCNA1,KCNA4,PSMA6,TAC1,TAC3,TACR1" Drug 6896_UP scriptaid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 49 176 "ABAT,ADRB2,NME5,APBB2,APP,ARNTL,BRINP2,ST3GAL5,SPAG9,SYNGR3,CREB5,PDE4DIP,CNTNAP2,CTH,DAPK3,PLPPR4,SLC12A6,MBNL2,TAOK3,PDLIM5,CSPG5,GLS,SPACA9,ACOT7,DIPK1A,ITGA7,VWA5A,LSS,MAP2,MAPT,MEF2C,MYO6,NEK1,NFYA,PCDH9,PFKFB2,SERPINI1,SYTL2,RGS4,WDR47,SOX15,SPTAN1,ELOVL4,RGL1,ACSBG1,SYT11,SYT1,RUNDC3B,SSBP2" Drug 3266_UP Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ACTN2,MTUS1,APBB2,PPFIA3,PPP4R4,DNAH17,ASPH,ATM,CACNA1I,BAIAP3,BTRC,B4GALT6,TAOK2,DNAJB5,ENTPD4,EDRF1,BRINP1,HP1BP3,DTNA,FCF1,ZNF589,C1orf61,PDLIM5,CAMKK2,DISC1,GLYR1,MSL3,GRB10,INPP5B,MAOB,MAPT,MDM4,KITLG,ADAM22,NF1,NUMA1,PALM,CDK14,SLC25A23,PLTP,MBOAT7,PTPA,MAPK8,KCTD17,SH3BP2,PLCB1,ARC,ATP11A,PSD3,PCDHA5,HEY2,TMPO,VGF" Drug 5569_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ADCY2,ADD2,AGT,AMPD3,APBA2,KCNAB2,MARK4,LDLRAD4,CFAP410,CACNA1D,HAP1,CAMK2B,KYAT1,CBFA2T2,KCNAB3,ZFYVE9,STOML1,NRG2,MFAP3L,SRGAP3,KBTBD11,DRD1,SGK2,CEND1,REEP2,OLFM1,AFF2,FOLR2,EFCAB2,GABRA2,GLYR1,GNAS,GRM8,IL6R,INPP5B,KCNMA1,KHK,NF1,P2RY1,GPR85,PNMA3,LRP12,POU3F2,ELOVL2,NKAIN1,SLC8A1,ZNF415,SPART,ATP10B,SYN2,WIPF1,XRCC4,ITM2C" Drug 6691_UP Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ADD2,KIDINS220,APAF1,APBB2,APC,ARRB1,ASCL1,BTRC,CACNA1D,CACNB4,DLGAP1,CACNA2D2,ADGRG1,TAOK2,HAPLN1,MICAL2,TOX,MFAP3L,SV2B,DLG3,ATN1,DTNB,DYRK1A,FRY,ING4,ZNF391,EYA1,ZNF589,SIGLEC8,GLI2,GPR22,GRIK5,SOX21,KLF12,TAGLN3,NEFH,PPP1R1A,PRKAR1B,CARF,SLC6A9,OGDHL,SOX10,ARHGAP26,TPM3,WIPF1,NSD2,KCNK12,ZIC3,ZNF74,SPHK2,LAMP5,ZNF225,SENP7" Drug 7048_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "AGT,AMT,PPP4R4,DNAH17,SLC4A4,SCAPER,CAMK2B,CHN2,DZIP3,DMPK,TRAPPC9,SIDT2,FAM13A,SUGP2,ETV1,DPYSL4,PRELID3A,HBS1L,B4GALNT1,DISC1,ATP8A2,USP19,POLL,SHISAL1,KHK,MAN2A2,MBD1,MEF2C,CNOT4,NPTX1,ODF2,PDGFRA,GPR85,POLG,PRKAR1B,PEX5,RNASE1,RPS6KA2,SCG5,ASAP3,PEX26,SLC9A5,SLC14A1,SORCS3,KIF13A,KDM4C,PHLDB1,ZMYND8,EIF4ENIF1,PLPPR2,WIPF1,EPM2A,SMIM8" Drug 6215_UP Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ASPHD1,ASIC1,ALCAM,SRPX,PPFIA3,ARHGDIG,ST3GAL5,BTRC,CACNA1A,ZFYVE9,ARHGEF6,ABI3BP,NRG2,PDE4DIP,DOCK4,DCC,ATN1,STX2,GABRA2,ERAP1,GLYR1,GLS,GNAO1,GNG4,PRUNE2,PCLO,RAPGEF1,TJAP1,IL6R,INPP5B,KHK,NF1,NNAT,ODF2,SERPINE2,MAPK10,GON4L,CEP97,RAD52,SLC1A7,LIMS2,SLN,RIMS1,MAPK8IP3,VAMP1,IQCE,SATB2,TMEM121,TMOD1,DAAM2,SYNC,MAP3K12,ST7" Drug 4664_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "AMT,FAM131A,SHROOM2,SCARB1,SYNGR3,FOXN3,TAOK2,ZFYVE9,ARHGEF10,PDE4DIP,CNTNAP2,DZIP3,DCAF8,KIAA0513,DAPK3,CNIH3,DLG3,EXOG,DMPK,MBNL2,ETV1,SEMA4D,SYT17,C1QL1,MSL3,IFI16,DIPK1A,MMP16,NDP,CNOT4,PCDH9,PRKAB2,FAM120C,RAD52,SUGCT,CSRNP3,ATXN1,ATXN7,SUPT20H,FUZ,ST6GAL1,IQSEC2,MAPK8IP3,PHLDB1,SUPT5H,ASTN2,TCF4,AP4E1,BHLHB9,CABIN1,SSBP2,SF1,EMSY" Drug 919_UP carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "AMH,BIN1,AMT,APBB2,ASCL1,KIF1A,ADGRB2,CACNA1D,CCK,ARHGEF2,CABP1,RCHY1,RGS6,CALY,RIMS2,AASS,EIF4G2,ERCC2,CDKL3,ST3GAL6,ZNF589,KIAA1109,CAMSAP1,IQCG,MALT1,GRM1,KPNA5,ADAM22,NF1,PIK3CD,RAD52,RGS12,KCTD17,SCN2B,MRAS,ASAP3,SLC20A2,WDTC1,SOX2,TSPYL2,CLSTN2,EPB41L3,INKA2,MAPK8IP3,SYT5,ATP11A,SEMA4A,PSD3,SEZ6L,TRIO,VIPR2,VLDLR,NLRP3" Drug 3269_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ABHD6,AP2A2,APBA2,APC,CASK,PLA2G4C,ATP6V0A1,NRP2,ST3GAL5,CBFA2T2,CDC42,CLGN,CHRNB2,LY86,EDRF1,RASSF2,RIMS3,RUSC2,LYPD1,DTNA,DMTN,FGF12,CAMSAP1,GAB1,ATP8A2,C1QL1,STON1,INPP5B,KCNN1,MATK,MYT1,PDE3B,NECAB2,RAB3IL1,RAD51D,RAD52,C1orf54,BSDC1,SH3BP2,ITSN1,CAMTA2,JMJD6,SMG6,SZT2,DOCK9,WBP2,FLRT2,VLDLR,XRCC4,ZBTB14,PRDM2,NT5M,KAT6A" Drug 2906_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "OGT,ANK3,AQP6,PPP4R4,PDE8B,MPDZ,BMP7,CAMK2B,INA,KCNAB3,CLGN,TAOK2,CLCN4,ABI3BP,VCAN,DZIP3,SV2A,DLG4,ELN,CORO2B,FCGRT,KAT8,FGFR3,AFF2,PRELID3A,ADAM28,GNG4,STON1,GSN,ATXN2L,ITPKA,KIFC3,VWA5A,NTRK2,ENPP2,PLCD1,RAB3A,ANKRD6,PREX2,EPN2,LIMS2,SHANK2,SLN,SPTAN1,RAP1GAP2,SPART,MTCL1,TNS1,KCNE5,CLIP2,ZNF154,SLC17A7,KCNAB1" Drug 6825_DN Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "RALGAPA1,ASPHD1,DOC2A,ARHGDIG,ARRB2,MARK4,ATP6V0A1,MTMR2,CACNA1D,CACNB2,CAMK2G,TAOK2,RAB28,VAX2,QKI,CSNK1E,FAM169A,PPP6R2,EDRF1,C2CD2L,RABGAP1L,EXOG,ACOT8,TOM1,POLR1B,FGFR1,CINP,OGA,MALT1,COPS8,GNG4,ATXN2L,IDH3A,KCNH2,MAP4,NRGN,PC,SLC25A23,PRKAR1B,PRODH,FAM184A,RNASEL,RPS6KA2,SH3BP2,NUBPL,SMTN,SLC20A2,RCOR3,ITPRID2,TCF7,TMEM121,PLPPR2,SMIM8" Drug 3028_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ADCY6,ASCL1,ATP1A3,BAIAP3,CAMK2A,BRSK2,CDH10,DNAJB5,FAM149A,COL9A3,RGS6,BRINP1,DCC,DYRK1A,ST8SIA3,HEYL,CACNG2,AFF2,DKK3,SIGLEC8,MYOZ2,CSDC2,GLI2,GPR37,ADAMTS8,GPR45,HNMT,HTR2A,HTR5A,KCNC1,KCND3,KCNH1,NF1,NTRK3,PTHLH,PTPRB,CCDC40,RASGRF1,FRMPD1,CCDC92,ST8SIA1,ABLIM3,KANSL3,SLC6A9,PALLD,TK2,RIMBP2,SEZ6L,LILRA4,TRIO,TRO,ZNF711,PMEPA1" Drug 3735_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "C1QTNF3,APC,CDC14B,CDK13,SLC4A4,ALDH7A1,C5,CACNA1A,ASIC3,NCOR2,CSF1,CTIF,RUSC2,AK5,SGSM2,EFNA3,ELAVL3,DMTN,FGFR1,SCARA3,SEMA4D,GNAS,GPM6B,HSF2,IL6ST,KCNMA1,MARK1,MDFI,ZNF862,NELL2,NPR2,ODF2,PDE3B,PPP5C,RAB3A,BEND5,ROM1,ZNF821,SLN,WDTC1,DOK5,MAPK8IP3,MLC1,TCF4,SZT2,METTL3,HIRA,VIPR2,ZNF32,MAP3K12,SEMA3B,DPF3,RNF146" Drug 2386_UP Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "BCL2L2,PROM1,HAP1,KRIT1,CBFA2T2,CHRNA4,TPP1,RUBCN,SEC14L5,RIMS3,GSDME,HEYL,EIF4G2,VPS13B,MTSS1L,CDKL3,F3,FGFR1,EFCAB2,FAM49B,GAB1,POLL,LILRB4,ICA1,C2orf72,JAK2,KCNJ5,KHK,VWA5A,TREM2,ENPP2,GPR85,PTN,RET,RGS3,TCP11L1,ASAP3,ZCCHC24,SPP1,PEG10,SS18,MAPK8IP3,DNMBP,CAMSAP2,PDLIM2,ARHGEF12,CRTC1,AP4E1,GPR161,TMOD1,TPM1,SSBP2,UBE3B" Drug 5416_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "CDC42BPA,PPFIA3,PPP4R4,ATP6V0A1,FOXN3,TAOK2,SLC4A7,CRY2,PPP6R2,C2CD2L,SMG7,RBM12,CELSR3,ING4,HSD17B14,FGFR1,BAIAP2,FHL1,DISC1,GPER1,GRIK5,HNMT,IGSF1,IL6ST,KCNF1,MMP16,NPTX1,KCTD15,SMIM7,PRKAR1B,ELOVL2,FAM120C,RAD52,GTDC1,RGS3,RGS12,ROM1,NEK11,SBF1,ABLIM3,SLC1A7,THSD1,STX1A,NSFL1C,VAMP1,ASTN2,SEMA4A,MCF2L,TMEM121,CHST8,ZMYND8,PLPPR2,ZNF74" Drug 5119_UP Prednicarbate [73771-04-7]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ACHE,DNAH17,ASTN1,ATP1A2,ATP1A3,B3GALT2,CADM3,ADAM23,ADGRB1,MTMR3,CACNG1,CAMK2B,CRLF1,AKAP7,CRMP1,CSF1R,VCAN,SEC14L5,RIPOR2,EXOG,DTNA,TOM1,ST8SIA3,PLXNC1,AASS,ING4,SRPK3,FGF1,DCTN2,SORBS1,TRAF3IP2,ERAP1,GFER,LYVE1,GNAL,GPD1,SPACA9,IRAK3,ICA1,NEUROD1,NOS1,PPP2R2B,GRAMD1C,ELOVL2,PTPRH,TMEM231,C1orf54,ZNF821,PKNOX2,KLHL4,PCDHA5,SEZ6L,VAV2" Drug 4597_DN Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "MRTFA,BIN1,CDC14B,ALDH4A1,NRP2,SCAPER,CFAP410,CACNA1A,CACNB2,CBFA2T2,CHM,TPP1,RAB26,HOMER3,PPP6R2,RUSC2,EDIL3,PLEKHO1,GAD1,GRK4,HLF,ITPKA,SCAMP5,MN1,GIT1,TNPO2,FA2H,POLG,GRAMD1C,CNNM2,GON4L,RIPOR1,GAL3ST4,TTLL7,TMEM156,BCAN,DZIP1,ANKRD6,LIMS2,ARHGEF40,ZNF334,ZNF667,ZHX3,ATP11A,ARHGEF12,DNAH7,CHST8,ZMYND8,OSBP2,VGF,VIPR2,MICAL1,PCBP4" Drug 3124_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ABHD6,BRAP,ADORA3,PLA2G6,MARK4,BACH1,BTRC,CAMK2G,SCARB1,JAM2,DNAJB5,CSF1,CSNK1E,TM9SF4,RUSC2,C2CD2L,RHOBTB1,EIF4G2,COQ7,CAMSAP1,CINP,CGREF1,SEPT9,RAB40B,GPR19,PCLO,MAP4,MEF2C,NINJ2,PDE4D,PLCD1,PLEC,SLC25A23,MAPK8,MARCH1,RAD52,ZC3H14,SS18,NCDN,JMJD6,EXOC7,PDLIM2,KIAA1107,TCF4,SYNE1,KCTD2,TPM3,NPDC1,ATP6V0E2,SPHK2,REEP1,MAP3K12,PRDM2" Drug 920_UP 5-aza-2′-deoxycytidine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "APAF1,APC,CFLAR,LDLRAD4,CACNA1D,SLC16A4,ARHGEF2,LRRFIP1,SRSF11,CHGA,CLCN3,NRG2,CREB5,ARHGEF4,CTNND2,RIMS2,HIPK3,SUGP2,MBNL2,EIF4G2,COQ7,MTSS1L,STX2,RRAGB,ST3GAL6,ERAP1,SEPT9,LPAR4,CNTRL,NR3C1,GRM8,MUM1,DHX35,HTR5A,KPNA5,MYH7,NF1,PLTP,ELOVL2,RAB3IL1,RAD52,KHDRBS2,RGS10,ARHGEF10L,SCN2B,SOX3,TROVE2,INKA2,SEMA4A,TCF7L2,TRIO,VAV2,ZNF45" Drug 4705_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "RALGAPA1,BIN1,CDK13,ATM,CCDC181,ATP2B3,ADGRB2,CA4,GPR37L1,CSF1,CHD5,GREB1,SMG7,SRGAP3,EDN3,EDNRA,OPTN,DMTN,MTSS1L,CAMSAP1,HPCAL4,FOXG1,SORBS1,OGA,DKK3,GAP43,NEU3,GRK4,GRB10,IRAK3,TJAP1,MEF2C,MID1,NEFM,CNOT4,RGS4,TCP11L1,FRMPD1,NLGN1,CCDC88A,SMARCD3,CLSTN2,TACR1,PCDHA5,TLL2,RIMBP2,ZMYND8,TUB,HIRA,VAV2,WIPF1,ITM2C,AP3B2" Drug 3828_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "NDRG2,ADCY2,TRMT9B,APBA2,MTMR3,CAMK2B,ZFYVE9,SULT4A1,PICK1,CNTN1,SNCAIP,GREB1,CTIF,TMCC2,DYRK1A,EDNRB,RASGRP2,STX2,ERCC2,PIPOX,CACNG3,FGFR3,CAMSAP1,C1orf61,C1QL1,RUNDC3A,ATF7,GPER1,HLF,ITGAM,PACRG,KITLG,MMP16,NUMA1,OLR1,PTAFR,ZSCAN32,FAM120C,PID1,KCNIP1,CPEB3,RBM34,NPAS3,MAPK8IP3,POPDC3,TBCEL,PIK3R5,CHST5,TRIO,VAV2,PRDM10,EPM2A,KAT6A" Drug 2861_UP Piracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ASIC1,ADORA3,ADRA1D,NME5,ALCAM,BIN1,APAF1,APOC1,PPFIA3,CDC14B,ADAM23,GYG2,BAIAP3,CAMK2A,HIP1R,ARHGAP33,RASSF2,CNIH3,MFAP3L,DUSP9,EFNA3,HSD17B14,ERCC2,NCALD,FOXG1,GPER1,GRIK5,BACH2,HTR2A,ICA1,KIF5A,BCO1,NDUFA5,NPTX1,TMOD2,SMOX,PLP1,RIPOR1,RALGDS,TRIM68,EMID1,RASA3,SH3BP2,ASAP3,SNCA,CLSTN2,ST5,INKA2,SMG6,ARHGEF12,CABIN1,VLDLR,SSPN" Drug 4393_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "SRPX,BIN1,ALDH4A1,CFAP410,ARHGAP33,QKI,PUM1,EDRF1,EXOG,SLC12A6,MBNL2,LRRC23,ERBB2,F3,KIAA1109,FHL1,FAM49B,GAD1,SYT17,PCLO,CACFD1,TJAP1,INPP5B,KCNJ3,KPNA5,LMO2,NF1,SLC11A2,SMIM7,STRN3,LRP12,PTCH1,PEX5,CEP97,RAD52,BSDC1,RGS12,CCDC25,ASAP3,FNDC3A,ZCCHC24,IQSEC2,AJAP1,SYNE2,PLCB1,ARC,TACC1,DMXL2,TRIM2,HIRA,LMF1,ZNF24,SSPN" Drug 6845_DN Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ASPHD1,ARID1A,AP2A2,AK2,LTBP4,AMPD3,CDC42BPA,CDK10,CAMK2G,CACNA2D2,ASIC3,TPP1,CREM,CSF1,SIPA1L1,CTH,RIMS2,PPP6R2,SLC12A6,DTNA,HIPK3,TNK2,DMTN,LRRC23,FGFR1,CAMSAP1,FHL1,SEMA4D,GNG4,IL6R,KCNJ5,KITLG,MMP16,NOS1,CNOT4,PLTP,PRKAR1B,ELOVL2,ZSCAN32,RGS12,RNASEL,CNKSR2,SLC9A5,COA1,EMC1,ARHGAP26,ARHGEF9,VPS13A,TCF7,PARD3,PLPPR2,PRDM2,SSPN" Drug 4387_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "AMT,APC,APLP1,CDC42,DNAJB5,CNTN1,FAM169A,ATN1,RCAN1,EGFR,ING4,ACSL4,DLC1,DPYSL4,ALDH1L1,SRCAP,ARFIP1,RUNDC3A,GLYR1,GNG4,CNTRL,CACFD1,NR3C1,GRM1,IL6R,KIT,MDM4,MOBP,NEUROD1,NF1,CNOT4,LRP12,MAPK7,MAPK8,ELOVL2,FAM120C,RAB5B,C1orf54,ZNF821,LIMCH1,EMC1,SPTAN1,TSPYL2,TROVE2,STX1A,DMXL2,PCDHA6,TMOD1,CABIN1,HIRA,FLRT2,WNK1,EMSY" Drug 3812_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ASPHD1,ADD2,EPB41L5,ALDH7A1,BACH1,BTRC,CAMK2B,CACNA2D2,CHM,PICK1,IQCK,IFFO1,TCEAL2,CNTNAP2,CTIF,MFAP3L,SPOCK3,DNM2,ECM2,DUSP9,EDN1,LRRC23,DENND4A,ETV1,FOXG1,PRELID3A,ZMYND11,MSL3,GNAS,GNG4,GPM6B,EML4,GRIK5,HSF2,JAK2,MATN3,MDM4,MEF2C,MN1,ODF2,PDE4D,SPATA6,ZCWPW1,KCTD17,RASA3,FAM214B,ZNF334,TNIK,NXT2,ZMYND8,VAV2,SMIM8,PHTF2" Drug 2444_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ALAD,APBB2,CASK,CDK13,ADAM15,SYNJ2,SCARB1,CLCN4,HOMER3,ARMC8,COL9A2,CREM,OSBPL3,HDAC9,ZNF337,DGKG,SPATA2,EFNA3,LPAR6,TNK2,TUBD1,RASGRP2,FHL1,FOXG1,INPP5K,SPACA9,TJAP1,IL6R,MDM4,NDUFA5,ENPP2,SLC25A23,RAB3IL1,RAD51D,ZNF493,ZDHHC14,TMEM206,EMID1,RASA3,FAM102A,SLC1A7,SMTN,CCDC88A,NXT2,KAZN,FBXW11,AHCYL2,THBS4,TLR4,TPD52,VIPR2,SPHK2,TFIP11" Drug 2089_UP Piroxicam [36322-90-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ASIC1,OGT,STX16,BACH1,RAB28,ABCG2,QKI,SDC3,DCAF4,SNPH,DAPK3,DBT,MFAP3L,HIPK3,ETV1,TAOK3,SCML2,KIAA1109,FGFR1,HPCAL4,WASF3,SESN1,GLI2,STON1,GSTM5,HSF2,ICA1,INPP5B,KIF5C,MATN3,GIT1,NEK1,CNOT4,OPCML,PIK3R1,STRN3,SPATA6,TNPO2,MINDY2,BCAS3,GAL3ST4,KIRREL1,UEVLD,ZBTB43,MAPK8IP3,TBL1X,TCF7L2,ICAM5,TMPO,TST,ZKSCAN5,XRCC4,PRDM2" Drug 3670_DN Kawain [500-64-1]; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "PKP4,APAF1,CDK13,SLC4A4,NRP2,CFAP410,HAP1,LARGE1,CACNA2D2,RAB26,NCOR2,PDE4DIP,ZNF337,PLPPR4,PARD6A,CDON,SGK2,MBNL2,WAC,ZNF589,FGF1,SCARA3,PDLIM5,GLYR1,HTATSF1,KCNJ5,MN1,GIT1,ZNF862,PCDH9,EPN1,MINDY2,PID1,ACSS3,RAD52,ENOX1,SCN8A,SH3BGR,PREX2,CDK5RAP2,LHPP,SS18,ARC,TBL1X,PSD3,ARHGEF12,TIMP4,TK2,RUNDC3B,RPRM,KCNAB1,PCBP4,PHTF2" Drug 7309_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "ADD2,AMT,EPB41L5,CDK10,MARK4,SYNJ2,CAMK2B,MAP7,RUNX1T1,CHM,CLTB,AKAP7,IQCK,CSF1R,PLCH2,VCAN,HDAC9,SPOCK2,DTNA,EGFR,EIF4G2,ING4,EPB41,MTSS1L,STX2,OGA,GABRA2,GRIK5,GUCY1B1,ATXN2L,KLF12,TJAP1,ZNF862,CCSER2,RETREG2,MINDY2,KCTD17,TTLL7,EMID1,AMBRA1,TMCC1,KDM4C,DDN,VAMP1,SYT5,ADGRL3,TRIM2,AHCYL2,DNAH7,TK2,VIPR2,VLDLR,KCNAB1" Drug 1650_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "SEMA6A,ANK3,APBA2,APP,CFLAR,CDK5R1,SPAG9,ZFYVE9,DNAJB5,HOMER3,AKAP7,WHRN,CSNK1E,DAPK3,DBT,LYPD1,SPOCK3,TMCC2,DSCAM,FCF1,EPB41L2,ANKMY1,FAM198B,BAIAP2,ZMYND11,ZNF276,MSL3,POLL,GRIK5,IRF8,JAK2,KIF2A,MEIS2,CNOT4,PALM,RETREG1,LRP12,MAPK8,ZDHHC14,RNASEL,FBXW7,MAP6D1,CLIP1,ASAP3,FNDC3A,SHANK2,SLC15A2,EFHD1,SPART,ARC,SYT1,VGF,EPM2A" Drug 3613_UP Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.92E-05 1.00E+00 3.92E-04 4.45E-03 53 195 "NDRG2,SEMA6A,LTBP4,MRTFA,BIN1,BRINP2,GYG2,CACNA1I,CACNA1D,HIP1R,USP2,NRXN3,NRXN2,SULT4A1,CSF1,CTIF,DCT,TMCC2,EDIL3,EN2,EFS,AFF2,RASL10A,RND1,HPGDS,GNAO1,LILRA2,GPR17,GRM1,PTGDR2,HNMT,SHISAL1,MGAT3,FXYD7,NF1,KCNK10,PLP1,TNPO2,LRRN3,PRKCB,GDPD2,ELOVL2,C1orf54,ASIC4,STUM,SLC6A8,HECW1,PEG10,ZBTB43,MAPK8IP3,SYN2,WSCD1,FLRT1" Drug CID000006946 2-nitroaniline Stitch 2.99E-05 1.00E+00 4.00E-04 4.55E-03 41 139 "ACHE,APAF1,APBB1,BCHE,BLM,CBS,INA,CHRM1,CLTC,CNR1,NCOR1,HDAC9,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,IGF1,OGG1,PAH,PCMT1,PENK,ABCB1,PACSIN1,PKIA,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SNCA,TAB2,PRTFDC1,JPH3" Drug ctd:C004648 testosterone enanthate CTD 3.00E-05 1.00E+00 4.01E-04 4.56E-03 127 575 "SERPINA3,NDRG2,ADCY6,USP31,MTUS1,NR0B1,OSBPL8,SRPX,ANK1,ANK3,API5,APP,PDXK,PDE8B,DDX3Y,EIF4G3,ATP2B1,MPDZ,DDR1,SPAG9,CBR1,USP2,RGN,SCARB1,NEURL1,CHGA,CLCN3,FAM149A,SLC4A7,FEZ1,PDE4DIP,PHF14,TCAF1,HEPH,EDNRA,EDNRB,SUGP2,MBNL2,LPAR6,EIF4G1,PLEKHA1,EXTL1,ST3GAL6,SEC23B,PCYOX1,SYNCRIP,SORBS1,SMC2,TRIM16,ZNF44,PCDH17,PPARGC1A,DHRS4,HTATSF1,FERMT2,PRUNE2,GPM6B,AP4S1,MUM1,SCRG1,IFI16,IGF1,IL6R,IL6ST,ITGAV,JAK1,JAK2,LIMS1,MAPT,MX1,MYH3,MYO9A,NEK1,CNOT4,OGDH,PDE1C,PDE3A,PDE4A,PDE4B,PDE4D,GPSM2,STRN3,PRKAB2,PRKACB,MAPK3,PROX1,PTN,PTPRD,USP47,C1orf54,SEC14L1,PPP1R9A,ABLIM3,SLCO1A2,SNCA,SNRPN,PALLD,USP33,CLUAP1,EMC1,ERC1,SRPK2,DIP2A,PRRC2C,ASTN2,CAMSAP2,TCF4,ZEB1,WASHC4,THBS4,CBX5,PARD3,TPD52L2,ELP5,TTC3,SGK3,AMOT,FLRT2,USP1,WIPF1,ZFP37,ZIC1,WNK1,ST7,ADAMTSL3,SSPN,FXR1" Drug 6405_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ADCY2,PDE8B,BRINP2,ATP1A2,NRP2,CFAP410,CACNA1E,CALB1,CHM,LY86,PCYT1B,PDE4DIP,ARHGAP24,RASSF2,MFAP3L,SGK2,HIPK3,ELAVL2,LRRC17,NCALD,SPEG,F5,PTK2B,TUBB4A,FGFR3,SEPT9,ALDH1L1,GPM6A,HRH3,HLF,MAP2,AFF1,MSI1,ADAM22,TAGLN3,PCDHGC3,PFKFB2,SMOX,SLC25A23,PLTP,LRP12,ZNF493,RNASE1,RTN1,HECW1,MCF2L2,AJAP1,ACSBG1,ATP11A,TCF4,DOCK9,TPM2,SLC30A3,PHTF2" Drug 2963_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "APBB2,FAM131A,MADD,ALDH4A1,SLC4A4,CDK5R1,FUBP1,ZFYVE9,NMT2,CLOCK,GPRASP1,ZNF337,TBC1D5,SHANK1,ECM2,ZNF549,FHL1,DCTN2,CSPG5,GATM,GPM6B,AP4S1,PADI2,MIA2,AFDN,MPP2,MSR1,NFYA,NNAT,PDE4D,RETREG1,ST8SIA5,PLCD1,PLP1,NECAB2,FAM120C,RET,SEC61A2,ZFHX4,RXRA,GALNT10,SH3BGR,NCDN,SEPT8,PDLIM2,ZNF34,RBFOX2,CDK20,SMUG1,KCNE5,UGT8,FLRT1,CLIP2,FZD3" Drug 5744_UP Calycanthine [595-05-1]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ASPHD1,AMH,APC,BCAS1,CDK10,SYNJ1,BAIAP3,CFAP410,CACNA1D,HAP1,CBS,INA,CHI3L2,KIAA1549L,HOMER3,PICK1,WHRN,COL9A2,CNTNAP2,PHF14,SPOCK2,MYEF2,RABGAP1L,EDN1,RCAN2,DMTN,APC2,CDKL3,SORBS1,ZNF44,DENND2A,ALDH1L1,RND1,STON1,VWA5A,TAGLN3,PDE4D,CNNM2,GDPD2,PTN,RFX2,FBXW7,STUM,ASAP3,ZNF334,SOX15,EMC1,COLGALT2,ELOVL4,ARC,SLC44A1,AMACR,ZIC3,PRDM2" Drug 378_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "RALGAPA1,MTUS1,ALAD,APBB1,EPB41L5,PPFIA3,AQP6,CADM3,ADAM23,SYNJ2,SEPT7,STOML1,PICK1,RIMS2,SIDT2,FAM13A,ING4,DMTN,KIAA1109,OLFM1,FYB1,SRCAP,ADAMTS13,SOX21,IRAK3,MAN1B1,KCNJ3,MOBP,NOS1,NTRK3,CLDN11,P2RX7,SMOX,MBOAT7,PPP5C,RLBP1,ZC3H14,FUZ,LIMS2,ZHX3,ZSWIM8,ZC3H13,ST5,PLCB1,WWC1,TCF4,TMEM151B,ARHGEF12,HIF3A,TSN,SLC13A3,ZBTB16,STMN4,CAMK1G" Drug 6283_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ADD1,KIDINS220,ALK,SEMA7A,MTMR3,CDH10,CHRNB2,CNTFR,PDE4DIP,DUSP9,EDIL3,EFNA3,EFNB3,PLXNC1,STX2,EFS,RRAGB,ABCA8,TESK2,GAD1,ZMYND11,INPP5K,USP19,GLI2,RAB30,GRIN1,ATXN2L,IL6ST,KIF5A,MOBP,ADAM22,NOVA2,NTRK2,SPATA6,POLG,POU3F2,PTCH1,MYH14,ATXN1,DZIP1,FAM214B,COA1,DDN,THSD1,PHLDB1,VPS13A,TK2,CDK20,HIRA,WNT7A,NDRG4,WNK1,PARP6,KCNAB1" Drug 4783_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "SERPINA3,ADCY6,KIDINS220,PLA2G6,DOC2A,MAP4K3,APBB2,ALDH4A1,GYG2,CFAP410,ARHGAP33,HOMER3,SH2B1,CSNK1E,PDE4DIP,SDC3,DCAF8,DBT,SMG7,EDNRA,FECH,ERAP1,GNG4,ELOVL5,HNMT,MAP4,MATK,MIA2,MITF,NOS1,SLC11A2,PLXNB1,PPP2R2B,PRODH,SAMD9,WDR25,FAM120C,NKAIN1,RGS3,RNASEL,SH3BP2,ABLIM3,TMCC1,IQSEC2,NCDN,TTBK2,ASTN2,ROBO3,WWC1,AHCYL2,TMOD1,XRCC4,MPPE1,PHTF2" Drug 6488_UP Bacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "APBA2,APOC1,RGS20,MARK4,ASPH,BRINP2,CADM3,CALB2,TPP1,STOML1,CNTN1,HDAC4,DGKG,SPOCK2,KBTBD11,ATN1,ST8SIA3,EGR3,AASS,FGF13,SORBS1,PRELID3A,OGA,DHX35,KIT,LSS,MID1,MMP16,NF1,CNOT4,ODF2,PALM,PLCD1,MTRF1L,PRPH,RELN,CCDC40,TRIM68,RGS3,SUGCT,FBXW7,SLC1A7,SLCO1A2,KIF13A,ZSWIM8,TRIM2,HEY2,TRPC3,TRPM2,VIPR2,WIPF1,LAT2,XRCC4,DNALI1" Drug 2449_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "NDRG3,KCNAB2,ARRB1,ASPH,ADAM23,NRP2,BMP7,CA8,THSD7A,CHM,RAB26,CNTFR,CNTN1,ARHGAP32,SV2B,HIPK3,FCF1,CNNM1,HEYL,EFNA3,MBNL2,C3orf18,EIF1,CDHR1,KAT8,HPCAL4,ANKFY1,ERAP1,RND1,ITIH2,KCNH2,MAP4,MBP,AFF1,NPPA,NPTX1,PDE4D,PFKFB4,PKIA,PTPRN2,PID1,BEND5,ZNF821,NTNG1,ZNF667,SS18,EXOC7,CAMSAP2,ATP13A2,CRB1,CHST5,KCNAB1,PAK5,NUP214" Drug 3030_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "SLC12A5,ADORA1,BIN1,DDO,AQP4,DDX3Y,CCDC181,NRP2,BMP7,CA12,REPS2,ARHGAP33,CHGB,PLPPR4,MAMLD1,EDN3,EFNA3,OLIG2,EFEMP1,FGFR3,CAMKK2,GAD2,LYVE1,GNAL,GRM1,NXPH3,KLF12,IL6ST,KCNH1,KCNJ3,MYBPC1,NPTX1,KCNK10,PCSK5,PLP1,PPARA,PTPRN2,RGS12,SEC61A2,ASIC4,FERMT1,BCAN,PREX2,TNIK,HECW1,UNC5B,WWC1,TBCEL,CUX2,PCDHGB6,TPM1,VAV2,KCNK12,PMEPA1" Drug 4787_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ACTN2,ALK,APBA2,APLP1,PPP4R4,BRINP2,BAIAP3,BTRC,CFAP410,ARHGEF2,FOXN3,CHN2,PLEKHB1,FADS2,AKAP6,ARHGEF4,JAKMIP2,MFAP3L,EDN1,EFNA3,MBNL2,SORBS3,EN2,KCNMB2,NCALD,SPEG,FABP7,ZNF589,FHL1,AGAP2,ERAP1,SIGLEC8,LPAR4,SYNPO,KCND3,KCNH2,KCNJ3,PIK3CD,PLCD1,DCHS2,SNRK,SEMA6D,PREX2,SMTN,KDM4C,UNC5B,PEG10,CDK19,RGL1,TGFBR3,TRO,FLRT2,MICAL1,EMSY" Drug 4432_DN "estradiol, USP; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "RALGAPA1,PLA2G6,LTBP4,BIN1,APC,APOC1,ASPH,ATP6V0A1,ADAM23,MPDZ,BMPR1B,SCAPER,COL9A3,NRG2,SH2B1,HAPLN1,PHF14,EDIL3,MBNL2,EZH1,FGFR1,CINP,OGA,ARFIP1,TDRKH,GPER1,EML4,HSF2,INPP5B,KIF2A,MEIS1,MIA2,MMP16,ZNF862,CNOT4,PBX1,PDE4D,PIK3R1,PLCB2,PTPRH,GTDC1,RGS7,WDTC1,EMC1,ASTN2,TBCEL,ZEB1,ZNF34,TMPO,VAV1,ZBTB14,ZNF32,PARP6,PHTF2" Drug 2995_UP Theobromine [83-67-0]; Up 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ABAT,ABHD6,ACTN2,NR0B1,AMPH,BCAS1,ATP2B3,CFAP410,HAP1,MAP7,JAM2,NRG2,HAPLN1,ABCG1,CSF1,CNTNAP2,DZIP3,GPRASP1,RIPOR2,EFNB3,FAM13A,EGR3,EIF1,DLC1,FLNC,GLYR1,SPACA9,IL1RAPL1,ATXN2L,KHK,LAMA2,MDM4,AFDN,PDE4D,CCSER2,BCAS3,PTPN13,ROM1,NEK11,LIMS2,KDM4B,TNIK,SYT1,SMG6,TK2,TPM2,TRPS1,SSBP2,KLC2,SPHK2,ZBTB38,SLC17A6,FZD3,SSPN" Drug 2787_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ADORA2A,PLA2G6,ALCAM,CDK13,SLC4A4,SYNJ2,SCAPER,BAIAP3,CACNA1A,CBFA2T2,NDST3,HOMER3,NRG2,CHD5,PDE4DIP,C2CD2L,SPOCK3,SGK2,DMTN,CAMSAP1,C1orf61,KHDRBS3,RND1,GNAS,ADAMTS13,GRM1,VWA5A,MMP16,NTRK3,CDK18,SERPINE2,PACSIN1,ZMAT4,RGS3,RGS12,MYH14,RPS6KA2,PPP1R9A,ST6GAL1,DZIP1,SLC1A7,SLC2A5,FAM214B,ARHGEF40,LIMCH1,KIF13A,EMC1,ARC,KIAA1107,PCDHGA10,CABIN1,CDK20,TRPM2,MKRN3" Drug 3569_UP Tropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "AMT,KCNAB2,MARK4,GYG2,CFAP410,CBFA2T2,EPS15L1,COL9A3,CSF1R,DCAF4,RIMS3,SPOCK2,CTIF,RABGAP1L,DMPK,DTNA,EFNA3,EFNB3,GPM6B,GPER1,KCNH2,KCNJ3,MGAT3,MX1,NF1,SLC25A23,CEP41,RELN,ZSCAN2,RGS12,TCP11L1,RPS6KA2,TRA2B,FBXO11,SLC9A5,COA1,SNCA,WDTC1,SPTAN1,CLSTN2,ARC,ATP11A,TBCEL,PCDHA6,CHST8,ZNF34,SLC44A1,ZMYND8,ZIC3,WNK1,EVI5,KCNAB1,PHTF2,SSPN" Drug 4605_UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "NR0B1,AK2,AQP4,PPP4R4,ATP2B3,CADM3,RHBDL1,SLC22A6,TMEM59L,FAM149A,ABI3BP,IFFO1,TCEAL2,RGS6,CX3CR1,TOX,ABCC9,EDNRA,ETV1,ANKMY1,FGFR1,AGAP2,NSG1,FYB1,GABRA3,GRM8,GPR45,HNMT,LYRM9,NEFM,PIK3R1,RETREG1,PMP2,STRN3,MINDY2,SNRK,MARCH1,TCP11L1,TRAPPC13,ANKRD6,SLC1A7,ARHGEF40,BTBD7,IZUMO4,ARHGAP26,NPAS3,ASTN2,MCF2L,PHF24,TLR4,TRPC1,TRPC3,PAK5,GAN" Drug 5494_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "AGT,APBB2,MARK4,RASL11B,SLC16A4,CNOT8,TPP1,CNTN1,VCAN,SMG7,SGK2,MBNL2,STX2,CORO2B,ZNF589,FECH,FGFR1,TPK1,STAG2,TXNL4A,TDRKH,RASSF8,IL6ST,KIF5A,LIG4,LMO2,MEF2C,TAGLN3,NPPA,NTRK2,OPCML,PTH1R,ZNF493,FBXW7,ABLIM3,SLC2A5,ARHGEF40,ELMO2,SOX2,TACR1,SEMA4A,ARHGEF12,CRTC1,TK2,TRPC3,HIRA,VAV2,KCNK12,SLC30A3,MAP3K12,GDPD5,KCNAB1,EPM2A,SSPN" Drug 4489_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ADCY6,ALK,MRTFA,DOC2A,AMT,IL33,BTRC,CBFA2T2,FOXN3,CNOT8,KIAA1549L,LY86,PICK1,AKAP7,ABCG1,CSF1R,PPP6R2,SNPH,KIAA0513,SIDT2,IRAK4,STX2,TUBB4A,IQCG,SORBS1,GAB1,TMEM8B,DISC1,INPP5K,KLF12,ITPKA,MAPT,MBD1,MEF2C,ADAM22,PRKAR1B,MAPK7,GRAMD1C,TMEM231,PID1,ZCWPW1,RGS10,NUDT11,SNCA,DDN,MAPK8IP3,SYT1,TIAM1,R3HDM1,CABIN1,TNS1,TPM2,PLPPR2,NT5M" Drug 3339_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "PLA2G6,BIN1,CDC42BPA,BCAS1,PPP4R4,MARK4,NUMB,SLC4A4,BTRC,CA4,CBFA2T2,SOCS6,TPP1,HOMER3,SLC4A7,CSF1,USP6NL,PARD6A,DSCAM,DTNA,FEM1B,OPTN,ING4,GLS,STON1,CNTRL,SPACA9,CACFD1,ITPKB,KCNJ5,KHK,NDUFA5,SLC11A2,CDK18,PRKAR1B,PRPH,WDR25,PTK2,PTN,CEP97,MORC4,RGS12,ANKRD6,IQSEC2,ELOVL4,PLCB1,POPDC3,MCF2L,KIAA0930,PCDHA6,AP4E1,TRPC1,ZKSCAN5,XRCC4" Drug 2116_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ARID1A,ADORA2A,KIF1A,CACNA1I,CACNG1,ARHGAP33,ARMC8,COL9A2,CREB5,AATK,MICAL2,SLITRK5,RIPOR2,FRMPD4,MYEF2,TRAPPC9,MTSS1L,ETV1,EZH1,FABP7,TUBB4A,C1QL1,GNG4,CACFD1,IL11RA,KCNN1,LMO2,MIA2,MYT1,GPR85,ZSCAN32,PTPRG,TTLL7,ZFP30,BTBD7,KDM4B,ZNF423,SPTAN1,ZBTB43,NCDN,MAPK8IP3,PHLDB1,MCF2L,EXOC7,TCF4,SYNE1,TIAM1,VIPR2,MAP3K12,EMSY,EVI5,STMN4,SEMA3B,DPF3" Drug 3806_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "LTBP4,TRMT9B,CDK13,BMP7,CACNA1I,C5,BAIAP3,CA8,HIP1R,RUNX1T1,CDO1,CHI3L2,SULT4A1,CNTN1,HAPLN1,CRY2,PLCH2,RIMS3,DMPK,TRAPPC9,ATN1,DTNB,SGK2,EZH1,BAIAP2,PDLIM5,ATP8A2,STON1,TPPP,KCNN1,KHK,MGAT3,MYH3,NRCAM,NECAB2,POU3F4,PPP2R2B,PRKCB,CNTLN,CCDC40,ZMAT4,RNASE1,PNMA8A,SEMA6D,SLN,FAIM2,ATP10B,DOCK9,ICAM5,TPM1,TMPRSS5,XRCC4,ZNF225,NT5M" Drug 5487_UP Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "RALGAPA1,ADCY6,BIN1,KCNAB2,SLC4A4,ALDH7A1,NRP2,MTMR2,BAIAP3,CNN3,CRY2,EDRF1,HP1BP3,LYPD1,TMCC2,DYRK1A,HSD17B14,VPS13B,FABP7,ZNF589,B3GAT1,GAD2,ERAP1,RUNDC3A,CNTRL,HNMT,TJAP1,KCNJ4,KCNJ5,LSS,GIT1,MSR1,NUCB1,POU3F4,PPP2R2B,PTPRO,RAD52,ZNF821,SH3GL3,ST6GAL1,SLN,DOK5,ZHX3,CLASP2,NSFL1C,SYT11,ASTN2,SMG6,KIAA0930,RPGRIP1L,CRTC1,LMF1,KCNAB1,MPPE1" Drug 1559_UP Spiperone [749-02-0]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "NDRG2,ADD2,PLA2G6,MRTFA,OGT,APBA2,KCNAB2,ARRB2,ALDH4A1,CFLAR,MTMR3,CCNT1,RCBTB2,SRSF11,B3GAT3,DPYSL2,ATN1,DTNA,SIDT2,ENO2,RASGRP2,IGSF6,CD320,F3,BAIAP2,POMT1,TRAF3IP2,GNG3,PRRC2B,LILRB4,DIDO1,BTN2A1,MBD1,OMG,CLDN11,P2RX7,PALM,PLCD1,MBOAT7,CNNM2,ACSS3,RAP1GDS1,PAQR6,SAFB,SH3BP2,SLC1A7,SLC11A1,TNIK,UNC5B,STXBP1,FAM168A,CHST5,REEP1,EPM2A" Drug 6472_UP Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ASIC2,CDC42BPA,APBB2,CAMK2A,TMEM257,NEURL1,DLGAP1,CHRNA4,TAOK2,CNN3,CNR1,WHRN,COL9A3,CTH,RIMS2,TOX,BRINP1,HP1BP3,RUSC2,SV2A,DTNB,DLC1,FOXG1,AGAP2,GALC,SIGLEC8,NEU3,SPACA9,HLF,HTR2A,KCNMA1,KIT,LMO1,PACRG,MMP16,NDUFA5,OPRL1,SLC25A23,PPP1R1A,PTHLH,ELOVL2,CCDC40,RYR1,SEMA6D,SLA,SLC2A5,PPP4R3A,SNAP25,SPP1,SYT5,HIF3A,PRMT8,VIPR2,WIPF1" Drug 7455_UP Panthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ALCAM,AMPD3,BIN1,FAM131A,PPFIA3,APP,ATP1A2,KIF1A,SYNJ2,BTRC,CACNA1D,CACNA2D1,CAMK2B,CAMK2G,CBFA2T2,CRLF1,CHRM4,CREM,TRAPPC9,ATN1,ST8SIA3,PHF20L1,TNK2,ZNF589,SEMA4D,EFCAB2,SYT17,GLS,HLF,KCNMA1,MMP16,LYRM9,MBOAT7,TNPO2,PRKCB,PTAFR,RIPOR1,RNASEL,FBXW7,SYNDIG1,PAQR6,SBF1,SMARCD3,UNC5B,ELOVL4,AJAP1,SEMA4A,MCF2L,THRA,TRPC1,LAT2,SLC30A3,PRDM2,KCNAB1" Drug 6740_DN Cyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ABHD6,SHROOM2,CDK10,MARK4,ATP1A3,SLC4A4,ADAM23,CAMK2G,ARHGEF1,RCBTB2,HOMER3,AKAP7,TENM4,SLITRK5,DZIP3,DLG3,EPHA5,DENND4A,ETV1,RRAGB,POLR1B,FYN,GLYR1,GPD2,GPER1,HNMT,SHISAL1,DIPK1A,INPP5B,MTR,NASP,NDP,PAK3,PRKAR1B,PRPH,APTX,CNTLN,PTN,SH3TC2,MRPS18A,SCG5,SLC14A1,ZKSCAN3,SMARCD3,LIMCH1,TNIK,CAND2,CEP68,KIAA0930,TCF7L2,PSD3,ZKSCAN5,ZNF189,MPPE1" Drug 5762_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "DPF1,TRMT9B,CDC42BPA,PRX,ALDH4A1,SCAPER,GYG2,HAP1,SYNGR3,NEURL1,CHI3L2,PLEKHB1,NRXN3,KIAA1549L,RAB26,HOMER3,CRMP1,RIPOR2,TOX,MYEF2,MFAP3L,C2CD2L,SPOCK3,DTNA,ING4,LRRC23,GAB1,DENND2A,RUNDC3A,COPS8,GPM6A,GRIK2,GSTM5,SMAD1,MATN3,NPR2,CEP41,PTAFR,PTN,FAT4,SUPT20H,PKNOX2,ASTN2,TBCEL,TMEM121,ZFPM2,TNS1,TRO,CA14,VAV1,ZIC3,ZNF24,STMN4,SLC17A7" Drug 3483_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "AK2,PLA2G6,C1QTNF3,APOC1,CDK10,ARHGDIG,ALDH4A1,SLC4A4,ATP6V0A1,RIPK1,CFLAR,BAIAP3,CBFA2T2,CDC42,CDH10,CHRNB2,PICK1,CSF1,MFAP3L,SIDT2,RUNDC3A,GLS,GNAS,GPM6B,SPACA9,TJAP1,KCNH2,MDFI,MIA2,ZNF862,EPN1,RAB3IL1,GTDC1,RGS12,EMID1,KCNIP1,SMTN,FAM214B,HECW1,INKA2,MAPK8IP3,PHLDB1,POPDC3,EXOC7,TRIO,VIPR2,ZNF24,REEP1,SYNC,WNK1,DNALI1,HPS4,ITM2C,TIGD6" Drug 6092_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "RALGAPA1,ASIC2,LTBP4,AMH,BIN1,ANK1,PROM1,GYG2,CDH2,CLCN4,CSF1,ATRNL1,SV2A,HS3ST2,SHANK1,MBNL2,ELAVL3,HSD17B14,RASGRP2,ERCC2,PTK2B,AFF2,RASL10A,PRUNE2,STON1,GRB10,GRIA4,GUCY1B1,SLCO1C1,PGAM2,CAMKV,PLTP,PPP5C,PRKCB,MAPK8,C1orf54,MYH14,RPS6KA2,ASIC4,DOCK10,SLC11A1,CDK19,VAMP1,SYT5,KIAA1107,ZEB1,SZT2,DOCK9,PIK3R5,TPM3,UBE3A,WIPF1,LAT2,FAM13C" Drug 3052_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "ABHD6,FAM135A,RGS20,FUBP1,CACNA1I,CALB1,NRXN1,CNTN1,DAPK3,MFAP3L,NTM,DLG3,DUSP9,ELN,KCNMB2,ETV1,KAT8,C1orf61,AFF2,DCTN2,PRELID3A,GAD1,MYOZ2,NEU3,ADAM28,PCDH17,ZNF276,TOX3,GUCY1B1,HTR2A,KCNQ3,MDFI,SLCO1C1,PDE1C,PPP2R5C,LRRC49,PTPRN2,FAT4,GAL3ST4,ROM1,SCN2A,SMTN,PKNOX2,SLCO1A2,ARHGAP26,NCDN,ACSBG1,SYNE2,TACR1,KAZN,TF,CHST8,ICAM5,TMOD1" Drug 5403_DN Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "APBB2,APLP1,APP,PPP4R4,BRINP2,ALDH7A1,MTMR3,ADGRG1,B4GALT6,CLU,HOMER3,ENTPD4,PDE4DIP,DAPK3,LYPD1,TRAPPC9,ATN1,RCAN1,SORBS3,BAIAP2,RUNDC3A,MSL3,KCNMB4,GRB10,GRIK5,PADI2,IL6ST,KCNF1,KCNH2,IPO5,MMP16,GIT1,NF1,RETREG1,MBOAT7,PRKAR1B,PRPH,TMEM231,SH3BP2,ZNF365,FAM214B,RBM34,WDTC1,NSFL1C,ATP11A,MCF2L,FBXW11,TRIM2,ARHGEF12,AP4E1,TK2,KCTD2,ZNF45,KAT6A" Drug 2704_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.02E-05 1.00E+00 4.01E-04 4.56E-03 54 200 "FGD2,RGS20,SYNGR3,CHRNB2,EPS15L1,CHD5,DZIP3,ZNF337,INTS1,DAPK3,PARD6A,DLG4,MBNL2,AASS,TNK2,SRPK3,VPS13B,RASGRP2,FER,PDLIM5,MSTN,PRUNE2,LILRA2,GPR19,GRIK2,ATXN2L,KLF12,IGSF1,ITGAM,KCNC1,KCND3,LSS,NINJ2,PMP2,POLG,PPP5C,MAPK7,MAPK10,DCHS2,RALGDS,RGS12,MYH14,SLC1A3,PKNOX2,SLC11A1,CAND2,TCF7L2,FAM189A1,ICAM5,RIMBP2,TRO,TRPS1,EVI5,PHTF2" Drug CID000083814 biotinyl-L-lysine Stitch 3.02E-05 1.00E+00 4.01E-04 4.56E-03 32 99 "SEMA6A,BSN,CALB1,CALB2,PPP1R1B,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3,NPY,PAH,PC,GPSM2,RNH1,SST,SYP,TACR1,TSC1,PORCN,GJC2" Drug CID000148184 CX516 Stitch 3.07E-05 1.00E+00 4.06E-04 4.62E-03 12 22 "CACNA2D1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,HTR2A" Drug CID000065959 Iomazenil (123I Stitch 3.07E-05 1.00E+00 4.06E-04 4.62E-03 12 22 "BRAP,CA4,GABRA1,GABRA2,GABRA4,GABRA5,GABRB3,GABRG1,GABRG2,ZEB1,SMUG1,RTN4" Drug ctd:C055494 caffeic acid phenethyl ester CTD 3.16E-05 1.00E+00 4.19E-04 4.77E-03 77 314 "SERPINA3,ADCY2,ADRA1D,MTUS1,KIF6,ARRB1,PROM1,SCAPER,CA4,CACNA1A,KALRN,CAMK2D,CD86,LGI1,NOG,CLOCK,CRMP1,RGS6,SLC45A1,DGKB,DBN1,OLIG1,RCAN1,E2F6,EDN1,KCNMB2,STX2,FABP7,HPCAL4,IP6K2,AGAP2,DISC1,GFAP,GFER,GHR,GJB1,GLS,PCSK1N,GNAL,GPR19,GRIK2,GRIK5,GSTT2,GYG1,ZHX1,ITGAM,KCNQ2,MXI1,MYO9A,NCAM1,NFIA,NFE2L2,NFYA,OLR1,OPA1,PCSK2,TMOD2,PFKP,POLG,PTK2,RET,RPE65,RPS6KA2,S100B,RPH3A,SLC6A9,SIRT2,SOX10,MPRIP,PARD3,TNNT1,ZNF384,ZFP37,KCNT2,DNAH10,GJC2,FRMD6" Drug 332_UP trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.18E-05 1.00E+00 4.21E-04 4.79E-03 51 186 "ACADM,ADD3,KIDINS220,MARK4,BMP7,RAB29,BAIAP3,WHRN,AKAP12,PDE4DIP,ARMCX2,DNAJC6,DRP2,EFNA3,EFNB3,SUGP2,MBNL2,STX2,PCYOX1,DPYSL4,FYN,CYP46A1,RAB40B,KIF3A,RNFT2,KIF5C,AFF1,MXI1,OMG,SERPINI1,PIK3CD,CCSER2,PLCD1,ZNF821,SH3BGR,SH3GL3,PPM1E,KIF16B,ASAP3,WDR47,FAM214B,PKNOX2,ZCCHC24,NXT2,ACSBG1,VAMP1,ACTR6,NPL,DNAJC12,PLPPR2,MPPE1" Drug 1228_UP geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.18E-05 1.00E+00 4.21E-04 4.79E-03 51 186 "ALK,N4BP2L1,MPDZ,KSR1,GYG2,CFAP410,NRXN3,CLU,ARMC8,COL9A3,ABI3BP,CPS1,CTH,EDRF1,DNAJC6,CNNM1,MBNL2,PLXNC1,SORBS1,PNMA2,GPM6A,DIDO1,CACFD1,SOX21,MUM1,MMP16,GIT1,ZNF862,NACA,NAP1L2,NF1,NFYA,OXTR,PENK,PRKAR1B,PTHLH,RGS4,HSPA4L,ANKRD6,SLC11A1,PDZD2,SOX15,ZC3H13,SPTAN1,IQSEC2,RAP1GAP2,TRIM2,SZT2,OSBP2,SEMA3B,PHTF2" Drug CID000000896 melatonin Stitch 3.18E-05 1.00E+00 4.21E-04 4.79E-03 102 443 "ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,AMT,KCNAB2,APLP1,ARNTL,ARRB1,ARRB2,NCOA1,CACNA1A,CACNA1B,CALM1,KRIT1,RGN,AIFM1,LRBA,COL4A5,CLOCK,CREM,CRHBP,CRY2,CSNK1E,BOC,GSDME,HS3ST2,DYNC1I1,NR1D2,KAT8,FOXG1,AGAP2,GFAP,MALT1,TCERG1,COPS8,INSM2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KAT7,TNFAIP8L3,HNRNPK,IGF1,KCNH2,MAOB,KITLG,MT3,NOS1,NPY,NOVA2,OPRL1,OXTR,PAH,PDYN,PENK,ABCB1,PACSIN1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,PRODH,RORB,CLIP1,SAFB,FOXRED1,SLC6A7,SLC11A1,TMEM132D,SST,ALG1,MGRN1,ZEB1,ARHGAP9,HHIP,KAT6B,TRH,TST,TTPA,CLIP2,KCNAB1,KAT6A,FXR1,JPH3" Drug CID005488970 Chrysamine-G Stitch 3.18E-05 1.00E+00 4.22E-04 4.80E-03 27 78 "APAF1,APLP1,CACNA1A,CACNA1B,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HSP90AA1,IGF1,OGG1,PAH,ABCB1,PACSIN1,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,PRTFDC1,JPH3" Drug CID000447564 Ph-F Stitch 3.23E-05 1.00E+00 4.27E-04 4.86E-03 42 144 "APLP1,APP,ALDH7A1,ATP6V0A1,CA4,CAMK2B,CAMK2D,CSNK1E,EBF1,TUBD1,TUBB3,TUBB4A,TUBA8,GFAP,POLL,TUBA1C,TNFAIP8L3,TUBB2B,MAP2,MAPT,MARK1,NEFM,NEFH,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,KANSL1,RELN,PPP2R3C,SNCB,SNCA,TTBK2,MCF2L,CABIN1,TUBB2A,TUBB1,UBC,LRP8,TUBA1A,KAT6A" Drug CID000001935 tacrine Stitch 3.23E-05 1.00E+00 4.27E-04 4.86E-03 42 144 "SERPINA3,ACHE,TKTL1,ADCY2,ADCY5,ADCY6,ADCY8,APLP1,APOC1,APP,BCHE,RUNX1T1,CHRM1,CHRNA4,CHRNB2,CLU,CNR1,CX3CR1,DMPK,CD320,PDLIM5,FUT9,GRIA1,GRIA2,GRIA4,GRIK5,GRIN2C,GRIN2D,GRM3,HRH3,HNMT,MAPT,NOS1,MAPK9,SLC1A2,SLC1A3,SLC1A7,SYP,TTPA,ZIC1,SLC17A7,NETO1" Drug CID004469372 AC1NBK9Q Stitch 3.27E-05 1.00E+00 4.33E-04 4.93E-03 17 39 "CALB1,ARHGEF1,B4GALT6,EIF4G2,GAP43,GFAP,KCNMB4,IL11RA,OPA1,EXOSC10,PRKCG,RNASE1,PBLD,STX1A,ACSBG1,SYP,PORCN" Drug 4283_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.29E-05 1.00E+00 4.35E-04 4.95E-03 52 191 "RALGAPA1,ACTN2,AK2,CDC42BPA,PKP4,APC,ASPH,ATM,ATP2B1,SPAG9,CLCN3,RAB26,SMG7,EXOG,EDIL3,FCF1,MBNL2,OGA,CRCP,FERMT2,AGFG1,IL6ST,KIF5C,MAP4,MMP16,MYO6,NFIX,NUMA1,RETREG1,STRN3,PKN2,PTN,SLC25A36,KIRREL1,SEC14L1,CCDC88A,ZNF667,KDM4B,SP4,BEX1,ZBTB43,PRRC2C,TBL1X,ZEB1,PSD3,DICER1,TMPO,KAT6B,SF1,WNK1,EVI5,KAT6A" Drug 4273_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.29E-05 1.00E+00 4.35E-04 4.95E-03 52 191 "KIDINS220,MTUS1,PKP4,ATM,ATP2B1,SYNJ2,CDC27,NMT2,CNTNAP2,GIT2,DBT,ZBTB24,SPOCK3,SIDT2,MBNL2,STX2,ANKFY1,DLL3,CRCP,RASSF8,AGFG1,IL6ST,MAP4,TM6SF1,NUMA1,PDE1C,PDE4A,CCSER2,PLCD1,STRN3,PMS2,PRKAB2,PTN,SLC25A36,FBXW7,SEC14L1,FBXO11,ZNF667,COA1,SPTAN1,PBLD,PSD3,SIK3,DICER1,CBX5,TMPO,NSD2,SF1,ZNF24,WNK1,PRDM2,MPPE1" Drug 4680_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.29E-05 1.00E+00 4.35E-04 4.95E-03 52 191 "AMT,SHROOM2,RGS20,CACNA1G,PLAA,ABCG2,IQCK,ABI3BP,SMARCAL1,ARHGEF10,DCAF4,FAM131B,CTIF,BRINP1,RHOBTB1,EFNA3,EIF5,IRAK4,CDKL3,AFF2,PNMA2,SYT17,LPAR4,GRM1,HNMT,MIA2,NF1,OPCML,PDE4D,RAB3A,SH3TC2,ZCWPW1,BEND5,RGS10,SUGCT,MCMBP,MAP6D1,FOXRED2,IL17RB,FRMPD1,ST6GAL1,PAAF1,ZNF365,SPATA7,DDN,CEP68,ASTN2,TK2,BHLHB9,TST,HPS4,KCNAB1" Drug 4328_DN Lanatoside C [17575-22-3]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.29E-05 1.00E+00 4.35E-04 4.95E-03 52 191 "CDC7,AK2,C1QTNF1,AMT,APC,RGS20,CAMK2G,LRRFIP1,RAB26,ABI3BP,SMARCAL1,SLITRK5,DCAF4,SNPH,ARHGAP24,RHOBTB1,CHRDL1,TRAPPC9,ATN1,FEM1B,EFNA3,SORBS3,ING4,MRNIP,PLEKHO1,ZNF589,FAM49B,KLF12,BACH2,ITPKB,KIF5C,MIA2,THYN1,ZNF862,OGDH,PDCD2,SAMD9,SNRK,RGS10,SUPT20H,ZNF365,FAM214B,SPATA7,FCHO1,ASTN2,CABIN1,ZMYND8,VIPR2,ZNF32,SPHK2,MAP3K12,SEMA3B" Drug CID000003291 ethosuximide Stitch 3.30E-05 1.00E+00 4.36E-04 4.96E-03 26 74 "ABAT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CREM,CACNG7,CACNG3,CACNG2,ZMYND10,MEST,HCN1,PKD1,PTCH1,RYR1,RYR3,MLST8,TPCN2,EPM2A" Drug CID000169317 "1,3-dipropylxanthine" Stitch 3.30E-05 1.00E+00 4.36E-04 4.96E-03 26 74 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ARSE,ALDH7A1,BSN,CACNA1A,CACNA1B,CACNA1E,P2RX6,ENTPD2,CHRM1,DRD1,GRIK1,GRM1,GRM2,GRM5,GRM8,NOS1,P2RY1,P2RY12" Drug CID000078017 I-As Stitch 3.30E-05 1.00E+00 4.36E-04 4.96E-03 45 158 "AS3MT,KIDINS220,APAF1,ARHGDIA,CNR1,HDAC9,DMPK,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,HVCN1,DNER,GFAP,PPARGC1A,TCERG1,GNAS,PACSIN2,HP,HPR,MBP,NOS1,OGG1,PAH,PDCD2,PENK,ABCB1,PLP1,PACSIN1,MAPK7,PRODH,PTAFR,PTPRN,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SNCA,SST,PRTFDC1,AAAS,JPH3" Drug CID000003373 flumazenil Stitch 3.30E-05 1.00E+00 4.36E-04 4.96E-03 21 54 "ABAT,CBR1,CCK,CCKBR,DBI,STX2,ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HTR2A,MEST,OPRL1,PTCH1,SLC6A1,SST,ZEB1,SMUG1" Drug CID000000106 pSer Stitch 3.35E-05 1.00E+00 4.41E-04 5.01E-03 38 126 "NFS1,SEPT7,CNOT8,BOC,IP6K1,ACOT8,DYRK1A,EEF1D,F8,PDLIM5,SDCBP2,INPP5K,GK,CBX1,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PTPN5,HP,HPR,MAP4,MYT1,PSAT1,PTH1R,PYGM,PCMTD2,SHMT2,TMEM132D,SPP1,JMJD6,SUPT5H,SYT1,CBX5,BHLHB9" Drug CID000086222 Spotlight Stitch 3.35E-05 1.00E+00 4.41E-04 5.01E-03 38 126 "APAF1,APC,CACNA1A,CACNA1B,CNR1,HDAC9,DBN1,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSP90AA1,IGF1,OGG1,PAH,PENK,ABCB1,PACSIN1,QDPR,CEP97,RGS3,FBXW7,ATXN7,FOXRED1,SLC1A3,SNCB,SNCA,SP4,PRTFDC1,JPH3" Drug CID000482140 5'-pCAA-3' Stitch 3.35E-05 1.00E+00 4.41E-04 5.01E-03 38 126 "APC,APOC1,ATM,ATP2A2,CACNA1A,ENTPD2,HP1BP3,DMPK,ATN1,DMTN,FCGRT,FECH,FGF14,CELF1,GAA,GALC,ATP8A2,GPM6A,CIT,KCNN3,PC,PPP2R2B,PRKCG,MAPK8,MAPK9,MAPK10,RNASE1,RYR1,ATXN1,ATXN7,SLC14A1,TAC1,TCF4,TNNT1,TTPA,UGT8,HPS4,FXR1" Drug CID000001641 phaclofen Stitch 3.39E-05 1.00E+00 4.41E-04 5.01E-03 25 70 "ABAT,CACNA2D1,CCK,SOCS6,SLC32A1,DBI,EIF4G2,PPP1R1B,CSPG5,GABBR1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,GLRB,GRIK1,GRIN2C,GRIN2D,MAP4,SLC6A1,SST,PRDM2" Drug 5629_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADCY2,NME5,AMPH,CDK13,KSR1,INA,CDO1,CNN3,NCOR2,MICAL2,CYBB,RASSF2,ATN1,AASS,ING4,EPHB1,FGF13,FUT9,RUNDC3A,GLRB,POLL,GRIK2,TJAP1,KCNK2,KCNQ3,MAG,AFDN,MMP17,OPRL1,CDK14,PLCD1,POU3F4,LRRN3,CEP41,MAPK10,GDPD2,CNTLN,NUDT11,SUGCT,PKNOX2,TSNAXIP1,ATP10B,RGL1,WSCD1,TRPC1,UBE3A,VAV2,BEST1,CLIP2,XRCC4,SLC30A3,KCNAB1,SLC17A6" Drug 4548_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "MRTFA,PPP4R4,ADGRB1,CFLAR,LDLRAD4,HAP1,CAMK2B,RHBDL1,NEURL1,LARGE1,TMEM59L,CSF1R,PDE4DIP,ERC2,CTNND2,DAPK3,SMG7,SPOCK3,CDON,DTNA,ST8SIA3,NRN1,F5,FGF1,GAP43,ERAP1,GNG4,TPPP,HPSE2,IRF8,KIT,NF1,NPTX1,NRCAM,PDE4D,PFKFB2,RETREG1,LRRN3,TCP11L1,KCNIP2,SUPT20H,KANSL3,DOK5,ZNF423,SPTB,PHLDB1,VAMP1,SYN2,MCF2L,PIK3R5,CHST5,SSBP2,VAV2" Drug 2530_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "C1QTNF3,APAF1,PRX,ASCL1,PDE8B,NOL4,MYRF,CBFA2T2,CHI3L2,NMT2,STOML1,CNTFR,CREM,CRY2,SIPA1L1,PPP1R16B,CTNND2,RUBCN,EDRF1,DOCK4,MFAP3L,GSDME,ST8SIA3,EDN1,SIDT2,FGFR3,FOXG1,FLT1,GAB1,GNG4,KCNJ5,MEF2C,AFDN,SAMD14,MYO6,FXYD6,SLC11A2,OPCML,P2RY1,DUSP26,MAPK10,RIPOR1,CARF,SCN2B,SEC14L1,SMTN,SLC11A1,SLN,SP2,CAMSAP2,UBE3A,FZD3,SENP7" Drug 6676_UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "DPF1,RALGAPA1,ADCY6,APOC1,ATP2B2,ATP6V0A1,RGS11,CFLAR,SYNJ1,CFAP410,HAP1,CAMK2B,CBS,CD86,SCARB1,EPS15L1,CLCN4,TMEM59L,CSF1,CHD5,PPP1R16B,C2CD2L,MAGI2,SRGAP3,ING4,EPHB1,CEND1,FAM198B,FDFT1,SORBS1,GAD2,GATM,GSN,HTR2A,CDH20,KCNJ5,KCNJ9,MAP4,TM6SF1,AFF1,NPY,PKN2,MAPK8,RASGRF1,ZMAT4,RGS12,SYNDIG1,SLC11A1,SPTB,TPM3,TUB,LAT2,KCNAB1" Drug 3448_DN Dienestrol [84-17-3]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "MRTFA,APBB2,ALDH4A1,MPDZ,CFLAR,CFAP410,CANX,B4GALT6,BAG4,CLOCK,FAM169A,TBC1D5,RIMS3,DNAJC6,TOM1,TNK2,EZH1,FAM49B,ARFIP1,GHR,FERMT2,GPD2,EML4,GPR37,KCNJ3,MIA2,KITLG,GIT1,ADAM22,NPR2,TMEM104,PTCH1,RAB5B,NEK11,FOXRED2,ITSN1,FERMT1,FBXO11,ITPRID2,SS18,FAM168A,TACC1,SEMA4A,TCF7L2,AHCYL2,TMPO,TSN,SSBP2,PLPPR2,VAV2,LMF1,MPPE1,PHTF2" Drug 6065_DN Suxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "NDRG2,NME5,APBA2,MARK4,ARHGEF7,SCAPER,CACNA1D,CAMK2B,CBFA2T2,SCARB1,CNTN1,SIPA1L1,PDE4DIP,DTNA,MBNL2,SORBS3,C3orf18,VPS13B,PRELID3A,GAB1,DISC1,INPP5K,GCNT2,GLS,GNAS,JAK2,LMO2,TM6SF1,MID1,MMP16,NF1,PDE4A,LRP12,PRKAR1B,MAPK7,WDR25,SEMA6D,SMTN,SLC6A8,BTBD7,SLC20A2,SNCA,THSD1,MAPK8IP3,ATP11A,TRIM2,TMEM121,TK2,ZNF711,ZNF45,EMSY,MPPE1,SSPN" Drug 2102_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "RALGAPA1,ALK,DOC2A,APOC1,BCL7A,ST3GAL5,LARGE1,CHM,ARHGAP22,ABCG2,QKI,CSF1R,ARHGEF4,CTNND2,MFAP3L,HS3ST2,ABCC9,SIDT2,OLIG2,PLEKHO1,CAMSAP1,ZNF44,C1QL1,SPIN1,GLRB,KCNMB4,SPACA9,GRIN1,GRM1,RASSF8,SHISAL1,IL6ST,PDGFRA,EPN1,PTPRH,FAM120C,ATG16L1,GAL3ST4,RGS4,KIRREL1,SLC9A5,CLASP2,COLGALT2,MAPK8IP3,TTBK2,TRIM2,HIF3A,TIAM1,TRPC1,EVI5,SLC17A7,PHTF2,DPF3" Drug 2440_UP Niridazole [61-57-4]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "SYN3,CDC14B,MPDZ,KSR1,SGCE,CFAP410,PICK1,WHRN,CNTNAP2,RIPOR2,RABGAP1L,ST8SIA3,EIF1,RRAGB,KIAA1109,OLFM1,FGFR1,KHDRBS3,GAB1,ERAP1,POLL,GPD1,GPR22,RNFT2,NCKAP1L,MYCN,OPRL1,PFKFB4,PPARA,CEP41,RELN,WDR25,CEP97,FAT4,RGS12,RNASEL,TCP11L1,SYNDIG1,RBM34,WDTC1,TNIK,HECW1,ZC3H13,ATP10B,SS18,INKA2,MAPK8IP3,SEPT8,PSD3,CRTC1,AP4E1,ZNF34,VAV2" Drug 7123_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "BRAP,AMPD2,APBB2,CDK10,RGS20,MPDZ,BCL7A,RAB29,CAMK2G,MAP7,KRIT1,SOCS5,PDE4DIP,SDC3,DCAF8,TBC1D5,SPATA2,DLG3,TRAPPC9,SUGP2,MBNL2,LPAR6,SORBS3,SCML2,FGFR1,ANKFY1,HBS1L,NCKAP1,DISC1,SMIM7,MAPK3,TMEM231,RAB3A,PID1,ZDHHC14,RFX5,MAP6D1,KBTBD4,TNIK,STX1A,EXOC7,FBXW11,KIAA0930,TCF7L2,ZEB1,ARHGEF12,TRPM2,HIRA,FAM155A,UBE3A,KLC2,HPS4,VPS35L" Drug 4403_DN Beclomethasone dipropionate [5534-09-8]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "BIN1,APBA2,PLA2G4C,SLC4A7,ENTPD4,AKAP12,ABCG1,SPOCK2,TRAPPC9,SLC12A6,OPTN,APH1A,SORBS3,ERCC2,BAIAP2,FHL1,GAB1,ERAP1,SRCAP,GNG4,TDRKH,CNTRL,NR3C1,HNMT,KHK,MDM4,KITLG,MOBP,GIT1,ADAM22,NEUROD1,PLCD1,STRN3,MAPK7,GRAMD1C,EMID1,BTBD7,SNCA,SPART,VPS13A,SEMA4A,EXOC7,SMG6,WSCD1,RPGRIP1L,SZT2,ZNF34,TMOD1,TRPC1,HIRA,VIPR2,FIP1L1,KAT6A" Drug 3049_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "KLRC4,SPARCL1,ASCL1,SLC4A4,MPDZ,DLGAP1,PLEKHB1,NRXN2,ABCG2,COL9A3,SEC14L5,EFNA3,AASS,SRPK3,VPS13B,REEP2,CACNG2,FGFR1,FGFR3,SIGLEC8,RUNDC3A,PCLO,SOX21,GUCY1A1,RASSF8,PTGDR2,HTR2A,HTR5A,SCIN,KCNC1,KCND3,KCNN1,LSAMP,ADAM22,PLXNB1,NECAB2,PPARA,PPP1R1A,PTH1R,CCDC40,RGS4,NUDT11,SCN8A,SLC6A9,SOX10,ZSWIM8,IZUMO4,PEG10,TIAM1,SEZ6L,TUB,KLC2,KCNK12" Drug 4335_UP Indapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "AQP6,CDC14B,BMP7,ST3GAL5,SLC16A4,PDE4DIP,CNTNAP2,C2CD2L,SMG7,SRGAP3,ELAVL3,ZNF549,APC2,DLC1,ATP8A1,KAT8,CAMSAP1,GAB1,DENND2A,RND1,FERMT2,ATF7,GRIK5,ITGA7,KCNB1,KCNJ5,MAP4,NPTX1,NTRK2,NUMA1,PDE2A,TNPO2,MED1,PRKAB2,CEP41,MAPK8,CCDC40,ENOX1,RFX2,TTLL7,TCP11L1,SEC14L1,SP4,HECW1,IQSEC2,LHPP,DMXL2,THRA,TIMP4,CDK20,ZMYND8,SF1,NT5M" Drug 2737_DN Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABHD6,AP2A2,CDC42BPA,APAF1,FUBP1,CACNA1A,CHM,QKI,HOMER3,CREM,DAPK3,DBT,FCF1,SIDT2,EFNA3,ING4,TUBD1,COQ7,RRAGB,ZNF589,PRKAG2,PDLIM5,CAMKK2,ZNF276,GPD2,LILRA2,GPR22,EML4,PADI2,INPP1,MAP4,CNOT4,PDE4A,CCSER2,PLEC,PTCH1,ZSCAN32,TMEM231,CEP97,ZNF821,SCG5,RGL1,STX1A,NSFL1C,TCF7L2,CRTC1,ZNF34,KCTD2,KAT6B,TPM3,TRPS1,SSBP2,ZNF225" Drug 3745_UP Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,SPARCL1,BCAS1,DNAH17,RASL11B,NRP2,CACNG1,INA,ADGRG1,LHX2,CLCN4,SULT4A1,AKAP5,NCOR2,EDRF1,MAGI2,DLG4,ATN1,DSCAM,ST8SIA3,EDN1,RASGRP2,AGAP2,FLT1,DPYSL4,GAP43,GFER,GPR75,GNG3,GSTM5,KCND3,LSS,MAP4,MMP17,ADAM22,NDP,NNAT,PLP1,PPARA,MAPK10,RAD52,RGS4,FNDC3A,SHANK2,SLC20A2,SPTAN1,SPTB,ARC,ADGRL3,CRTC1,FLRT2,SLC13A3,PARP11" Drug 2005_DN Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADD1,BRAP,PLA2G6,PKP4,MTMR2,ZMYM4,CHRNB2,TAOK2,DCAF8,ZNF337,SMG7,RABGAP1L,TRAPPC9,ABI2,EPB41L2,IGSF6,CEND1,FAM49B,FYN,TRAF3IP2,GAP43,LILRA2,JAK2,MYO9A,NACA,NEK1,OCRL,GPSM2,STRN3,MAPK3,VPS13C,C1orf109,C1orf54,ATXN2,FAM214B,CCDC88A,KBTBD4,SMARCA4,SMARCC2,DOP1A,UNC5B,SPTAN1,TAB2,ATP10B,NCDN,DIP2A,MCF2L,FAM208A,TCF7L2,HIRA,LAT2,ZNF24,PRDM2" Drug 7222_DN Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "RBM10,KIDINS220,AK2,ASPH,FOXN3,HOMER3,ARHGEF6,SLC4A7,CREM,SOCS5,APPL1,RABGAP1L,DMPK,TRAPPC9,DSCAM,SEZ6L2,FEM1B,SIDT2,SORBS3,COQ7,DENND4A,VPS26C,BAIAP2,FAM49B,INPP5K,TXNL4A,BTN2A1,RNFT2,INPP5B,MAPT,MBD1,MYO9A,SLC25A23,LRP12,RIPOR1,TMEM231,SUSD4,FBXW7,RPS6KA2,SBF1,NUBPL,DOP1A,SOX3,ZSWIM8,ERC1,ZBTB43,ASTN2,ATP11A,TRPC1,EVI5,WIPF2,EPM2A,RNF170" Drug 4294_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ACTN2,PKP4,PDE8B,N4BP2L1,ATP6V0A1,ADAM23,BMP7,MTMR3,CACNA2D1,HAP1,SLC16A4,CDH8,CNR1,TOX,RIMS3,DCT,SPOCK3,RABGAP1L,FCF1,SEMA3D,ETV1,ERAP1,ALDH1L1,GDF9,GPM6B,GUCY1B1,HTR2A,SCIN,KCNJ5,MBP,CD200,NF1,NNAT,PCBP3,CDK14,LRP12,MAPK8,ZSCAN2,CCDC40,ZCWPW1,RGS4,ROM1,CPEB3,SLC12A4,RBM26,TCF4,DMXL2,PCDHGA1,TMPO,ZMYND8,CADM1,LAT2,KCNAB1" Drug 4257_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "MTUS1,BIN1,APBB2,CDK10,SLC4A4,SCARB1,SRSF11,CHN2,QKI,HOMER3,ENTPD4,ARHGEF4,DBT,KLHL3,PLPPR4,PARD6A,DYNC1I1,DPH1,FCF1,COQ7,SPEG,ETV1,FGF13,TRMO,PNMA2,GLRB,GPD2,PCLO,KLF12,HNMT,IL11RA,DIPK1A,LIG4,NDP,RC3H2,PPP5C,PTCH1,FAT4,TCP11L1,LGR4,AP1AR,SCG5,SLC1A3,TNIK,CAND2,SPTAN1,ZBTB43,SAMSN1,WWC1,TRIM2,ZNF34,WIPF1,NSD2" Drug 5232_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASIC1,RBM10,CDC42BPA,APP,CDK10,ASPH,CACNA1I,BAIAP3,CFAP410,FADS2,NRG2,HAPLN1,PDE4DIP,NOS1AP,RIMS3,INTS1,RUSC2,SMG7,ATN1,SIDT2,EGR3,TNK2,DMTN,CAMSAP1,DLL3,RASSF8,IRF8,KCND3,MAP4,ZNF862,NOVA2,SMOX,TNPO2,TMEM104,RGS10,SH3BP2,AMBRA1,ARFGAP1,ZCCHC24,ARHGAP26,SPTAN1,CAMTA2,MAPK8IP3,STX1A,KAZN,PCDHA5,PARD3,TRIO,SF1,WNK1,EVI5,SEMA3B,KAT6A" Drug 3360_UP Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "LTBP4,ST3GAL5,CACNA1I,BAIAP3,LDLRAD4,ARHGEF1,TPP1,CRYM,SPOCK2,MBNL2,EGR3,AASS,ZNF589,KIAA1109,FGFR1,CAMSAP1,GLS,GPD2,TDRKH,INPP5B,KCNN1,AFF1,TAGLN3,NEFM,TMOD2,PPP1R1A,RAB3IL1,RAD52,C1orf54,TRIM68,MYH14,ASAP3,FNDC3A,SLC6A9,BTBD7,CXXC4,COA1,ZCCHC24,SP4,ARHGAP26,RGL1,AJAP1,SYT5,OBSL1,TNS2,GPR161,TMOD1,TNS1,TRPM2,WIPF1,LAT2,DNALI1,SLC17A7" Drug 1708_DN Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASPHD1,AP2A2,LTBP4,APBB2,CFLAR,BMP7,ARHGEF7,BTRC,EDRF1,EIF5,FER,FGFR1,FGFR3,BAIAP2,CAMSAP1,NOP56,OGA,AHDC1,MALT1,GLS,HTATSF1,DHX35,ICA1,KIF5C,MAP4,MBD1,MITF,GIT1,NPR2,RIPOR1,DCUN1D2,RPS6KA2,FERMT1,FAM214B,WDTC1,ZBTB43,KIAA0930,TRIM2,CRTC1,PCDHA6,AHCYL2,CHST8,CABIN1,CDK20,HIRA,UBE3A,PLPPR2,VAV1,KLC2,ZBTB14,EMSY,SMIM8,NUP214" Drug 2510_UP Etanidazole [22668-01-5]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADD2,AGT,PPP4R4,PDE8B,ALDH4A1,LDLRAD4,CALB2,HIP1R,EPS15L1,NRXN2,TMEM59L,DNAJB5,CABP1,NRG2,CREM,MICAL2,DGKG,TRAPPC9,DTNB,EFNB3,PLXNC1,COQ7,DLC1,SIGLEC8,GFER,KCNMB4,GSN,GUCY1A1,HTR2A,KCNC1,KCNF1,KCNN1,NCAM1,CNOT4,MTRF1L,MAPK10,RIPOR1,BEND5,MYH14,ROM1,ASAP3,PKNOX2,LIMCH1,SOX10,SYP,TCF7L2,AHCYL2,CRB1,LILRA4,UBE3A,VAV2,LMF1,WNT7A" Drug 5060_DN Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ARID1A,EPB41L5,CDK10,SLC4A4,BTRC,MAP7,SOCS6,PLEKHB1,CLCN4,TPP1,NMT2,QKI,HAPLN1,CSF1R,AK5,EXOG,RCAN1,MBNL2,STX2,CDKL3,ETV1,F3,FOXG1,GLRB,TDRKH,GPER1,CNTRL,KIF5C,MPP2,NF1,PLCD1,FA2H,PPARA,CNNM2,ZSCAN2,RAB3IL1,BEND5,GAL3ST4,MAPK12,SBF1,CSRNP3,SCN8A,DZIP1,PEX26,SLC14A1,THSD1,SYT11,DNMBP,ATP13A2,GPR161,SSBP2,CADM1,ZNF45" Drug 5871_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ALK,PPP4R4,ASCL1,CCDC181,EPS15L1,NRXN3,CLCN4,RAB26,AKAP6,CSF1R,CSNK1E,SDC3,BRINP1,MFAP3L,SPOCK3,SRGAP3,ST8SIA3,AASS,ST3GAL6,FYB1,SEPT9,GPD2,CACFD1,GRM8,PTGDR2,SCIN,KCNN1,MATN3,MDFI,AFDN,MOBP,NOVA2,MAPK7,PROX1,CNTLN,TMEM231,CCDC40,ROM1,DZIP1,SLC1A7,SLN,DOK5,SPP1,DICER1,PRMT8,TRH,TRIO,RUNDC3B,UGT8,ZNF74,REEP1,PRDM2,KCNAB1" Drug 3804_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADCY6,NLGN4X,AMPH,PRX,ARSE,CDK13,CADM3,BMP7,STOML1,COL9A3,CSF1R,CHD5,CTNND2,SMG7,DTNB,ABCC9,FRY,EZH1,ABCA8,CAMSAP1,AGAP2,PDLIM5,DKK3,MYOZ2,ATXN2L,TJAP1,ITGA7,CDH20,KCNF1,KCNJ5,KCNN1,SMAD1,MBP,MGAT3,AFDN,NF1,NPPA,P2RX7,WDR25,KHDRBS2,RFX2,RGS12,SEMA6D,SH3BP2,SLA,SHANK2,SLN,DOP1A,MAPK8IP3,PHF24,TRPC3,PARP6,JPH3" Drug 3452_DN Methacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "OGT,CDC42BPA,FAM131A,APP,CDK5R1,BTRC,CFAP410,CANX,ZFYVE9,PLAA,CLCN3,QKI,HINFP,SIPA1L1,GPRASP1,HDAC4,KIAA0513,MFAP3L,PARD6A,SGSM2,TRAPPC9,DTNA,BAIAP2,GCNT2,GLYR1,RAB30,CNTRL,GRB10,NR3C1,ATXN2L,INPP5B,IPO5,MBD1,MPP2,ADAM22,NFYA,RETREG1,CNNM2,ELOVL2,ZSCAN32,RGS10,TMCC1,KDM4B,TSPYL2,SPART,PLCB1,TACC1,ANKRD12,AHCYL2,ZNF32,C12orf4,EPM2A,SMIM8" Drug 2645_DN Droperidol [548-73-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "DOC2A,CDC42BPA,APBB2,CDC14B,ALDH4A1,BCL7A,BMP7,ST3GAL5,CFAP410,QKI,CDC42BPB,SIPA1L1,DCAF8,KIAA0513,DTNA,CDKL3,F3,FER,FGFR3,AGAP2,ANKFY1,ERAP1,INPP5K,HNMT,DHX35,KHK,MAP4,NF1,PPP2R5C,RAB3IL1,ZDHHC14,MYH14,EMID1,SBF1,AMBRA1,PEX26,KDM4B,SOX3,ZHX3,TSPYL2,ARHGEF9,VPS13A,TACC1,ANKRD12,EXOC7,IQCE,KIAA0930,TCF7L2,ZNF34,CADM1,PLPPR2,PRDM2,HPS4" Drug 4154_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "DPF1,AK2,PLA2G6,LTBP4,BEGAIN,ANK2,APLP1,ATM,CFLAR,MTMR3,SLC16A4,CNTNAP2,RIMS3,GSDME,HS3ST2,DTNB,EDNRA,SORBS3,KCNMB2,FOXG1,AGAP2,NSG1,OGA,GNAL,GRM1,ATXN2L,KCNB1,KCNJ5,MID1,ZNF862,TREM2,SNTG1,PKN2,MAPK7,PTCH1,ELOVL2,ACSM5,RAD52,BEND5,NUDT11,ST6GAL1,PKNOX2,SLC14A1,SNCA,ZBTB43,ATP10B,JMJD6,PCDHGA10,CRTC1,ZNF34,TRIO,LAT2,NT5M" Drug 3738_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADCY2,ADD2,ADORA1,APBB1,PPP4R4,SLC2A11,KSR1,BAIAP3,CLCN4,DNAJB5,PICK1,FAM149A,CREM,NCOR2,DSCAM,SEMA3D,FRY,EGFR,RCAN2,IGSF6,CDKL3,GFER,GFRA1,POLL,GNAL,STON1,GRM7,HLF,IGFBP1,L1CAM,AFDN,NTRK2,OMG,PDE2A,PDE4D,PLXNB1,PPP2R2B,CEP41,RGS4,RPS6KA2,CSRNP3,ATXN1,FNDC3A,SLA,SPTAN1,NFASC,INKA2,DMXL2,TRIM2,HEY1,TK2,PLSCR4,PARP11" Drug 7512_UP CP-863187 [668981-07-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "LTBP4,ANK1,APBB1,KCNAB2,GAS7,SHROOM2,CDC14B,DNAH17,CFAP410,CA12,CHRNB2,STOML1,PHF14,CTIF,HEPH,KBTBD11,EDIL3,SGK2,DMTN,FGFR1,SCARA3,FOXG1,TRAF3IP2,GALC,GAP43,NXPH3,PTGDR2,ITGA7,KCNJ5,KIF5C,MAPT,ZNF862,SLCO1C1,SLC11A2,PDE4A,PFKFB2,PIK3R1,EPN1,PPP5C,PRKAR1B,MAPK7,RAB3IL1,CCDC40,ZDHHC14,MYH14,AMBRA1,CLSTN2,MAPK8IP3,TIAM1,TMPRSS5,VAV2,VIPR2,WIPF1" Drug 2913_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ANK3,APBB2,PPP4R4,MPDZ,CA12,BRSK2,INA,CLGN,CHI3L2,COL9A3,ABCG1,ARHGEF10,SV2A,EDNRB,OPTN,SORBS3,ELAVL3,TNK2,FOXG1,SRCAP,KCNMB4,GNG3,FERMT2,GRIK5,NXPH3,SCRG1,ITPKA,MAPT,AFDN,ZNF862,NEFM,NOS1,CNOT4,PDE2A,POU6F1,CEP41,MASP1,SYTL2,RAB3A,SEC61A2,EMID1,ASIC4,SH3BP2,FAM102A,SLN,WDTC1,PEG10,LHPP,SYT11,SYNE2,UBTF,KCNAB1,KAT6A" Drug 3461_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASPHD1,SEMA6A,AMT,SEMA4G,ARHGDIG,PLA2G4C,RASL11B,SLC2A11,ATP6V0A1,CACNA2D1,HAP1,NEURL1,CHM,PICK1,ENTPD4,SH2B1,TOX,GIT2,SMG7,GNE,VPS13B,FGFR1,CAMSAP1,IQCG,PDLIM5,GAP43,SRCAP,GFER,RND1,FICD,KLF12,MAP4,ADAM22,OGG1,PIK3CD,PRKAR1B,MAPK7,ZSCAN2,RAD52,ZDHHC14,SUPT20H,SLC20A2,SNCA,ZHX3,TTBK2,PLCB1,SYT5,TCF7L2,TRIM2,SLC30A3,GDPD5,SEMA3B,ITM2C" Drug 5465_DN Pivampicillin [33817-20-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ALCAM,APC,CAPRIN2,SLC4A4,SCAPER,MTMR3,CAMK2G,LRRFIP1,RAB28,AKAP7,ZNF337,DLG3,ATN1,RCAN1,E2F5,EDNRA,CNNM1,PLEKHO1,EPB41L2,SCML2,FHL1,NOP56,SEPT9,SRCAP,GPD2,GPR19,NUDT21,SPACA9,KLF12,ELOVL5,KHK,MAP4,TM6SF1,MITF,MPP2,MYO9A,PRODH,TMEM104,PEX5,RAD51D,GTDC1,RXRA,FOXRED2,ATXN2,RBM34,CDK19,SAMSN1,TTBK2,PHLDB1,EXOC7,ATP13A2,THRA,CDK20" Drug 6288_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "APAF1,PPFIA3,KALRN,LHX2,NRXN3,CNTFR,PDE4DIP,MAML1,BRINP1,RCAN1,EFNA3,EFNB3,COQ7,KCNMB2,RRAGB,ABCA8,ST3GAL6,C1orf61,PNMA2,B3GAT1,GABRA2,DENND2A,GAD2,ERAP1,RUNDC3A,GRIK5,HNMT,IL6ST,IL11RA,KCNB1,MT1M,MYL3,CNOT4,NPR2,NUMA1,ODF2,ENPP2,PTCH1,PTPRE,RGS12,MYH14,GSTCD,SH3BP2,NTNG1,SLA,CCDC88A,SLC11A1,SLC20A2,SNCA,ZHX3,SP4,ZBTB14,KCNAB1" Drug 6504_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ACTN2,LTBP4,MRTFA,ATP6V0A1,RGS11,LDLRAD4,CACNA2D1,CAMK2A,CAMK2B,CTH,GREB1,SPOCK2,GIT2,RCAN1,DTNA,EDNRA,EFNA3,EFNB3,AASS,TNK2,FOXF2,ANKFY1,AFF2,NSG1,OGA,GALC,HPGDS,GLS,GNAS,IL6ST,KCNN1,ELOVL2,PTPRB,TRIM68,DCUN1D2,GSTCD,SYNDIG1,SBF1,ASIC4,CNKSR2,PREX2,ACSBG1,ROBO3,EXOC7,TRIM2,SYNE1,ZNF34,BEX4,CDK20,LAT2,NSD2,SLC30A3,GDPD5" Drug 3208_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ARID1A,GRAMD1B,ALK,APAF1,CCDC181,SLC4A4,ATP2B2,CADM3,SYNJ1,BTRC,RHBDL1,CBFA2T2,CNTN1,COL9A3,VCAN,SPOCK3,ST8SIA3,EDNRA,PLXNC1,TENM1,ZNF589,PRELID3A,ATP8A2,SRCAP,RND1,GRIK2,INPP5B,KCNC1,VWA5A,MAP2,MBP,MYCN,CNOT4,NPPA,GPR88,CDK14,PLXNB1,PILRA,PRODH,PTAFR,CCDC40,SH3BP2,SLC11A1,SNCA,SOX10,HECW1,TAL1,PCDHGA1,OBSL1,TEX15,SEZ6L,PRDM2,GDPD5" Drug 2681_UP Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ACTN2,ADCY2,MTUS1,CDC14B,ATP2B2,MYRF,SYNGR3,CDH10,GPR37L1,CHI3L2,TAOK2,NRG2,SIPA1L1,PPP1R16B,DGKG,SPOCK3,ATN1,DYRK1A,USH1C,HIPK3,EFNA3,MBNL2,LPAR6,HPCAL4,FOXG1,GABRA1,GABRA2,TMEM8B,ADAM28,GRK4,GRIK2,GRIN1,GSN,HPSE2,ICA1,KCNJ3,MDM4,MOBP,TAGLN3,MYT1,NTRK3,OMG,PHKG1,CCSER2,SEPT4,PPP2R2B,RTN1,FERMT1,SLC8A2,TRPS1,LAT2,CAMK1G,JPH3" Drug 4833_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,BIN1,APBB2,MARK4,CA4,NMT2,WHRN,SH2B1,CNTNAP2,CTNND2,GIT2,MFAP3L,SGSM2,RABGAP1L,EDNRA,SIDT2,COQ7,MTSS1L,ERCC2,FGFR1,FAM49B,TPK1,KHDRBS3,ERAP1,POLL,GPER1,EML4,PCLO,ELOVL5,BRINP3,INPP5B,NCAM2,NTRK2,PPARA,PPP2R2B,PPP2R5C,FAM120C,SLC1A7,EPN2,BTBD7,SNCA,UHRF1BP1L,SEMA4A,TCF7L2,TRIM2,SZT2,TMOD1,TPM1,ZMYND8,XRCC4,SPHK2,KCNAB1,EPM2A" Drug 4723_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADORA2A,DOC2A,APBB2,ADAM23,BTRC,CAMK2B,RAB28,ZFYVE9,CSF1R,HDAC4,RIMS3,DAPK3,CTIF,BRINP1,RUSC2,SPOCK3,CDON,DTNA,OPTN,ATP8A1,FYB1,TMEM8B,SRCAP,GFER,GLS,MSL3,PCLO,HNMT,KCNF1,KCNN1,MAPT,ADAM22,NEUROD1,NF1,LRP12,MAPK7,ELOVL2,PTN,FAM184A,FBXW7,SH3BP2,KIF21B,EMC1,MAPK8IP3,ASTN2,EXOC7,TMEM121,AP4E1,TK2,PARD3,VIPR2,SYNC,DNALI1" Drug 5833_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABR,AMT,APC,APOC1,SLC4A4,CFLAR,CDK5R1,BTRC,HAP1,ARHGEF2,ASIC3,CHRNB2,CNOT8,NRXN3,CLU,QKI,ATRNL1,VCAN,KBTBD11,CHRDL1,SGK2,ANKMY1,SCML2,GLRB,GNAS,GPM6B,ICA1,KIFC3,MIA2,GIT1,TAGLN3,MX1,PPP5C,ELOVL2,PID1,ROM1,TCP11L1,NCBP3,ZFP30,ASAP3,SLC2A5,TMCC1,SOX2,ARHGAP26,CEP68,PCDHA5,CADM1,ZNF711,REEP1,ZNF225,PARP6,SEMA3B,NUP214" Drug 3847_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "LTBP4,TRMT9B,SEMA4G,MTMR3,CACNA1I,CAST,CHN2,CHRNB2,PICK1,CNTFR,CNTN1,NRG2,DAPK3,HS3ST2,DRD1,DTNA,USH1C,EN2,PTK2B,DLC1,FOXG1,C1orf61,AGAP2,SRCAP,GLYR1,GPER1,GRIA4,GRM7,ATXN2L,KLF12,HSF2,IRF8,LSS,NF1,CLDN11,PFKFB2,PRKAR1B,RGS12,RYR1,SEC14L1,SELL,DOCK10,BCAN,SHANK2,KIF13A,TSNAXIP1,POPDC3,TBCEL,THBS4,PIK3R5,KCNAB1,NUP214,JPH3" Drug 403_UP alpha-estradiol; Up 200; 0.01uM; ssMCF7; HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "NDRG2,ADD2,ADORA2A,KCNAB2,BCAS1,AQP6,PDXK,RASL11B,FGF17,HAP1,CD86,CD38,NEURL1,PCYT1B,CSNK1E,ATRNL1,SDC3,CYBB,CHRDL1,RCAN1,EYA1,C1orf61,FOLR2,ALDH1L1,CYP46A1,PTPRT,IGF1,KCNJ5,KCNQ3,MAOB,NAP1L1,SLC11A2,NTRK3,PDE4D,PLXNB1,PTPRN,RGR,RGS4,RNH1,SYNDIG1,ABLIM3,RPH3A,LIMS2,ZKSCAN3,NMNAT2,SPTB,LMO3,SSTR2,AJAP1,ATP11A,TRIM2,TLL2,TRPM2" Drug 2035_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "MTUS1,C1QTNF1,BIN1,CDC42BPA,APAF1,SEMA4G,ARNTL,MARK4,CAPRIN2,ST3GAL5,RAB29,CAST,CRMP1,FEZ1,CX3CR1,DOCK4,DLG3,DSCAM,FAM13A,ABI2,LPAR6,EPS8,ZMYND10,KIAA1109,FGFR1,ARFIP1,TXNL4A,SLC2A6,PADI2,KHK,KIF5C,SCAMP5,NEK1,CLDN11,RETREG1,TMEM104,RAP1GAP,ROGDI,ARID4A,SATB1,ZSWIM8,CEP68,RGL1,STXBP1,TCF7L2,ARHGEF12,AHCYL2,ZMYND8,TSN,ZNF45,REEP1,LMAN2L,ITM2C" Drug 5331_UP Rolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADCY6,AGT,AK2,C1QTNF3,SEMA6A,MARK4,CACNA1I,BAIAP3,ARHGEF1,NEURL1,ARHGEF2,CHN2,QKI,DZIP3,DSCAM,PLEKHO1,EZH1,FER,BAIAP2,IQCG,FYB1,GAP43,ZNF276,GLYR1,MSL3,FERMT2,NR3C1,ATXN2L,ELOVL5,DHX35,HSD17B1,MAP4,MAPT,LYRM9,NF1,PDE3B,NLE1,PLCD1,PRKAR1B,TMEM104,RGS12,PNMA8A,ZNF821,RPH3A,KDM4B,ZCCHC24,TK2,FAM155A,PLPPR2,VAV2,MAP3K12,HPS4,MPPE1" Drug 6286_DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "CDC42BPA,APLP1,ASPH,ADAM15,BCL7A,RAB29,SLC4A7,NRG2,PPP6R2,TOX,RASSF2,RHOBTB1,SIDT2,ST3GAL6,TACC2,POMT1,FYN,DISC1,INPP5K,GBX2,MSL3,GNG4,GPR37,IDH3A,DIPK1A,KCNMA1,KIF5C,MEIS1,PIK3CD,FSD1,PRPH,CNNM2,PTX3,SH3TC2,CCDC25,ZC3H14,SCG5,KIF16B,SLC1A3,IFT122,WDTC1,SPATA7,ELOVL4,STX1A,ROBO3,PDLIM2,CABIN1,RUNDC3B,HIRA,TRIM9,UPF3A,NAV3,ACTR3B" Drug 3705_UP Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "LTBP4,AQP4,CDC14B,RASL11B,ADAM23,NRP2,CACNG1,P2RX6,TAOK2,EPS15L1,HOMER3,CNTFR,TCEAL2,CSF1,IPCEF1,CHD5,RIMS3,ST8SIA3,NCALD,ST3GAL6,NSG1,TBR1,SRCAP,GNAL,GNAO1,GNG3,GRM1,GRM2,ICA1,TJAP1,IL6ST,KCNJ4,AFDN,MMP16,ADAM22,NNAT,OPCML,PRKAR1B,PTH1R,MAPK12,FUZ,RPH3A,SLC11A1,KIF21B,AJAP1,SYT11,DOCK9,SLC44A1,ICAM5,SEZ6L,ZIC3,REEP1,PRDM2" Drug 2767_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ARID1A,NME5,SEMA6A,ALCAM,MARK4,N4BP2L1,SYNJ1,SYNJ2,GYG2,CACNA1I,HAP1,CAMK2B,HOMER3,AKAP7,SLC4A7,SH2B1,EDRF1,HP1BP3,KBTBD11,DTNA,DYRK1A,DLC1,KIAA1109,FHL1,CAMKK2,OGA,GRM2,HNMT,KCNB1,KCNJ5,MAP4,NF1,CLDN11,ELOVL2,SYNDIG1,RYR1,SFPQ,ASAP3,SLC11A1,ZCCHC24,SPTB,SAMSN1,POPDC3,ATP11A,DMXL2,CRTC1,CHST8,TRPM2,FAM155A,XRCC4,NDRG4,EMSY,PHTF2" Drug 2258_DN Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABAT,ASIC1,APOC1,PPP4R4,ATP6V0A1,BLM,MTMR3,GYG2,SPAG9,FOXN3,FAM189A2,CNTN1,SLC4A7,EGFR,ZNF589,FGF12,FGFR1,FAM49B,SRCAP,AHDC1,SPIN1,GRIK5,ARHGAP19,IL6ST,INPP5B,MAP4,ZNF862,CNOT4,NUMA1,OGG1,PIK3R1,PPP2R2B,PPP5C,RAB3A,RAB3IL1,ZDHHC14,PAQR6,SEC14L1,ZNF821,ANKRD6,BTBD7,SNCA,ZBTB43,NCDN,STX1A,PRRC2C,PCDHA6,TMEM121,AP4E1,NDRG4,WNK1,KCNAB1,NUP214" Drug 7240_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "FZD9,AP2A2,SYT13,APAF1,APBA2,PPP4R4,CCDC181,ATP1A2,MYRF,RUNX1T1,ARHGEF2,ZFYVE9,BAG4,ARHGEF10,CNTNAP2,SDC3,ARHGEF4,MFAP3L,EXOG,EFS,F5,AGAP2,GABRA1,GATM,SRCAP,SPACA9,GRM8,KCND3,KCNF1,KCNMA1,AFDN,GIT1,ADAM22,BCO1,MYO7A,NF1,SLC11A2,ELOVL2,RGR,EMID1,RASA3,FRMPD1,ASAP3,SYBU,PHLDB1,ATP11A,DOCK9,SLC19A3,PARD3,PIK3R5,ZKSCAN5,PLSCR4,PHTF2" Drug 7049_DN AH6809; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABHD6,ANK3,ASPH,ALDH7A1,RIPK1,NRP2,SYNJ2,CA12,SPAG9,PLEKHB1,CHRNB2,NMT2,QKI,IQCK,CHD1L,VCAN,FAM131B,TBC1D5,GIT2,DBN1,DSCAM,EDIL3,RGS17,FHL1,ERAP1,GART,GLYR1,PCLO,AGFG1,TJAP1,IL6ST,JAK2,MBNL1,NDUFA5,PLEC,SYTL2,RPS20,FUZ,CCDC88A,BTBD7,SLC20A2,SMARCD3,KDM4B,TNIK,DOK5,SPTAN1,COLGALT2,SS18,SZT2,TNS1,RBFOX2,METTL3,WIPF1" Drug 7044_DN GSK-3 Inhibitor IX; Down 200; 0.5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASPHD1,AP2A2,BIN1,CDC42BPA,GAS7,BRINP2,ATP6V0A1,SCAPER,CACNA1I,RUNX1T1,QKI,CNTFR,SLC4A7,CSF1,DZIP3,CTH,DTNA,EGR3,SORBS3,PDLIM5,OGA,ERAP1,ALDH1L1,GLYR1,RAB30,KCNF1,MGAT3,ZNF862,NF1,PDE1C,RETREG1,RGS3,RGS10,TCP11L1,RPS6KA2,EMID1,ZNF821,ASAP3,BCAN,BTBD7,WDTC1,HECW1,VPS13A,SZT2,CHST8,TK2,TMOD1,PARD3,VGF,REEP1,UPF3A,SEMA3B,PLSCR4" Drug 667_UP 6-mercaptopurine monohydrate; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABHD6,BIN1,ASCL1,N4BP2L1,NRP2,BMP7,ST3GAL5,RAB29,SEPT7,CDH8,ADGRG1,CHRM4,TMEM184B,RAB26,CNTN1,CRYM,ECE2,MBNL2,KCNMB2,ATP2C1,GAB1,RUNDC3A,CNTRL,PADI2,KHK,TAGLN3,MYL3,NOVA2,GPR173,MED1,PTH1R,QDPR,RAB3A,RAP1GAP,RGS3,RNASE1,KLHDC8A,GSTCD,SLC2A5,KBTBD4,SNCA,CAND2,SPART,LMO3,ATP10B,CAMTA2,ZC4H2,PHF24,SIRT1,TNS1,TFIP11,WNK1,NUP214" Drug 5236_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "LTBP4,APBB2,DNAH17,ASPH,CFAP410,HAP1,ARHGEF1,DNAJB5,NECTIN3,ENTPD4,CRY2,CSF1,RIMS2,SMG7,KBTBD11,CDON,MBNL2,FAM198B,KIAA1109,CAMSAP1,FHL1,FOXG1,GPR153,FUT9,GLYR1,RAB30,GPM6A,GPER1,GRIK5,KCNMA1,KCNN2,MBD1,ADAM22,MX1,ZNF862,PFKFB2,EPN1,RETREG2,ZFHX4,MYH14,SYNDIG1,ASAP3,SLC2A5,SNCA,ZCCHC24,PLCB1,TACC1,BEX4,PIK3R5,CHST5,TRPC1,ZKSCAN5,LAT2" Drug 918_UP ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ARID1A,ADORA1,AP2A2,SPARCL1,MRTFA,ARRB1,CFLAR,BTRC,ARHGEF2,CHRNA4,LHX2,VAX2,ARHGEF4,RIMS2,HDAC4,CTIF,MFAP3L,DTNA,EDNRA,CNNM1,MBNL2,ERCC2,ST3GAL6,FGFR1,FGFR3,CAMSAP1,STON1,NR3C1,GRM1,SLC2A6,IRAK3,HNMT,LMO2,KITLG,NLE1,PTHLH,RAD52,RNASEL,SCN2B,ZCCHC24,TSNAXIP1,CAMTA2,INKA2,VAMP1,ASTN2,SEMA4A,TNS2,THRA,TRIO,RPRM,VAV2,PRDM2,NLRP3" Drug 4499_UP Clidinium bromide [3485-62-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABAT,ACTN2,BEGAIN,BCAS1,CDC14B,ASCL1,ATM,NRP2,CFLAR,CACNG1,INA,STOML1,COL9A3,AKAP5,TCEAL2,NCOR2,CSF1,ARHGEF10,PDE4DIP,RIMS3,DRP2,DTNA,DYRK1A,PIPOX,FGF12,LYVE1,SPACA9,CACFD1,AP4S1,SOX21,ICA1,MAN2A2,MMP17,ZNF862,NPR2,PDE4D,RETREG1,FEZF2,RGS10,KCTD17,MYH14,FRMPD1,CPEB3,SLA,SLC2A5,SLC6A11,RBM34,RBM26,MCF2L,SLC44A1,THRA,TPM3,VIPR2" Drug 363_UP sodium 4-phenylbutyrate; Up 200; 100uM; HL60; HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "NDRG2,OGT,NCOA1,CADM3,ATP6V0A1,CBFA2T2,ARHGAP33,CHRM4,CLTB,SULT4A1,RAB26,C2CD2,ARHGEF4,RIMS2,ECE2,MAML1,BRINP1,HP1BP3,DLG3,ING4,STX2,FGFR1,OGA,RUNDC3A,BTN2A1,SOX21,KLF12,ICA1,FXYD7,NFYA,PLCB2,PLEC,C1orf109,RIPOR1,RGS12,RLBP1,KLHDC8A,MAP6D1,FOXRED2,ITSN1,KDM4B,ZCCHC24,ZSWIM8,ZC3H13,SPART,SS18,VAMP1,HIF3A,AMOT,FLRT1,PLPPR2,SLC13A3,SLC17A7" Drug 4628_DN Crotamiton [483-63-6]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,TRMT9B,BIN1,AMT,APC,ATP2B2,CACNA1I,BTRC,CFAP410,SCARB1,SYNGR3,LARGE1,TAOK2,QKI,HOMER3,ARMC8,ATN1,MBNL2,EN2,KIAA1109,FGFR1,CINP,ZNF44,MSL3,GPM6B,GPR17,IL11RA,INPP5B,MITF,NF1,NNAT,PDE4D,FA2H,GRAMD1C,GON4L,PTN,TMEM231,ATXN7,FRMPD1,SLC1A7,SIRT2,CCDC88A,WDTC1,EMC1,IQSEC2,ZBTB43,THSD1,TRIM2,ARHGEF12,RIMBP2,RUNDC3B,XRCC4,EVI5" Drug 3972_DN Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADORA2A,NME5,AMPD3,EPB41L5,GAS7,SEMA4G,CACNA1A,USP2,SLC16A4,CBFA2T2,SCARB1,ARHGEF2,CLGN,DNAJB5,CPS1,CSF1,PDE4DIP,RIMS2,CYBB,MFAP3L,CDON,EDN1,EDNRA,EFNB3,ING4,VPS13B,FGFR1,KHDRBS3,RND1,GPER1,ADAMTS13,BTN2A1,GSN,KCNN1,KHK,ADAM22,NUMA1,MTRF1L,LRP12,MAPK8,PTHLH,TRIM68,SEMA6D,PREX2,SLN,ARHGAP26,VPS13A,AHCYL2,VIPR2,ZFP37,SYNC,SLC17A7,PLSCR4" Drug 5058_UP "Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ALK,SEMA7A,APAF1,ADAM23,RGS9,NRP2,CFLAR,LDLRAD4,RUNX1T1,CNTFR,WHRN,CTNND2,PYGO1,PHYHIP,MFAP3L,DPP6,COQ7,F5,AGAP2,GAB1,GNAO1,ADAMTS13,GRIK5,GRM7,KIT,MOBP,MSI1,NCAM1,NNAT,NOVA2,NPPA,OGG1,PALM,RETREG1,EPN1,LRRN3,SAMD9,RGS10,RGS12,KCTD17,ST6GAL1,CNKSR2,SLC1A7,SNAP25,SNCA,SPP1,UNC5B,SYP,ZFPM2,TRIO,TUBB1,VGF,WNK1" Drug 4676_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ARID1A,MTUS1,CDC14B,ATP1A3,SYNJ1,SCAPER,LDLRAD4,NRXN3,ARMC8,SLC4A8,TCEAL2,ARHGEF10,PDE4DIP,CNTNAP2,SMG7,RABGAP1L,ATN1,CNNM1,LPAR6,HSD17B14,EPB41L1,LRRC23,GNG3,LPAR4,GUCY1B1,IFI16,IGFBP1,MDFI,ADAM22,NEK1,NEUROD1,NF1,PRKAR1B,PTPRB,FAM120C,TMEM231,RALGDS,KHDRBS2,RGS7,ZNF671,ANKRD6,CCDC88A,SLC20A2,SOX2,TSNAXIP1,SOX15,IZUMO4,UNC5B,IQSEC2,PLCB1,KIAA1107,TK2,RUNDC3B" Drug 2741_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "BIN1,PPFIA4,DNAH17,ASPH,MPDZ,KSR1,DLGAP1,CHGA,CHRNA4,DNAJB5,HAPLN1,NCOR2,AATK,SIPA1L1,PPP1R16B,ST8SIA3,SEZ6L2,HEYL,FHL1,SORBS1,ZNF44,SIGLEC8,SEPT9,GRK4,GRIK2,KLF12,KCNC1,KCND3,MGAT3,AFDN,MMP16,MYO6,NCAM1,NPY,PPP1R1A,KHDRBS2,FRMPD1,CCDC92,ZNF415,SOX2,SYT1,SYT5,TACR1,TRIM2,SEZ6L,TRIO,TRO,UBE3A,LMF1,KCNK12,XRCC4,ZNF711,SEMA3B" Drug 2248_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "PLA2G6,SEMA6A,CDC42BPA,APOC1,PLA2G4C,MARK4,CACNA1I,CAMK2B,NEURL1,PLEKHB1,CHRNB2,CNOT8,SLIT2,DNAJB5,ARHGEF6,AKAP7,CSF1,CSF1R,CTIF,MFAP3L,CNNM1,EIF4G2,DMTN,ZNF589,KIAA1109,FHL1,SRCAP,GLS,GNG4,CNTRL,GSTM5,INPP1,MAP4,MPP2,ADAM22,SERPINE2,ZSCAN2,C1orf54,RGS10,CNKSR2,PEX26,SMTN,EMC1,ST5,PLCB1,ROBO3,WSCD1,TMOD1,TRIO,CADM1,VIPR2,SEMA3B,TIGD6" Drug 3999_UP Gramine [87-52-5]; Up 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASPHD1,APBB2,APOC1,AZGP1,MPDZ,NRP2,BAIAP3,CDC42,NRXN3,AKAP5,TCEAL2,CSF1,DZIP3,SGSM2,TENM1,DLC1,ATP8A1,KIAA1109,FGF1,CAMSAP1,FLT1,FYB1,SIGLEC8,NEU3,GRK4,IL6ST,KCND3,MATN3,AFDN,RETREG1,MED1,PPP5C,MASP1,ATG16L1,GAL3ST4,GSTCD,RTN1,MRAS,KIF13A,TNIK,SSTR2,AJAP1,SYT5,EXOC7,TAL1,SLC44A1,R3HDM1,VGF,VIPR2,SF1,WNK1,DPF3,JPH3" Drug 4236_DN Gabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,TRMT9B,APC,PPFIA3,CDK10,TAOK2,PLAA,RAB26,CSNK1E,PPP6R2,ARMCX2,ATN1,DTNA,MBNL2,SORBS3,MTSS1L,EZH1,SEMA4D,ZNF44,RUNDC3A,GRM1,MAPT,MEF2C,ADAM22,NPR2,NRGN,PLXNB1,PRKAR1B,ELOVL2,ZSCAN32,PTPRB,FAM120C,RAB3A,RGS4,RGS10,KIRREL1,SBF1,ATXN7,FRMPD1,FAM214B,KANSL3,ELMO2,TSNAXIP1,DOK5,ATP11A,TCF7L2,TPM2,ZMYND8,OSBP2,VGF,WNK1,KCNAB1,TIGD6" Drug 3506_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASIC2,SRPX,ALK,APBA2,APLP1,ATP2B2,MTMR3,CACNA1D,NECTIN3,CSF1R,APPL1,DOCK4,RIPOR2,SPOCK2,JAKMIP2,ELMO1,TMCC2,HIPK3,PLXNC1,FHL1,MALT1,GLS,GPD2,STMN2,RAPGEF1,NR3C1,KIF5A,MDM4,BCO1,NAP1L1,NPPA,P2RX7,PAH,SNTG1,PPP5C,MAPK10,PTCH1,FAM184A,KCTD17,TCP11L1,RPS20,ASIC4,SELL,CPEB3,SLC1A7,ZCCHC24,TROVE2,MAPK8IP3,KAZN,TEX15,DAAM2,SLC17A7,KCNAB1" Drug 3094_DN S-(+)-ibuprofen [51146-56-6]; Down 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,APOC1,MARK4,ASPH,CAMK2B,CDO1,B4GALT6,JAM2,ZFYVE9,CREM,SLITRK5,CTIF,ECM2,PLXNC1,F5,KAT8,OLFM1,FYB1,GABRA2,TRAF3IP2,WASF3,GATM,GRM1,MAN1B1,KCNN1,MAP4,MEF2C,ZNF862,NF1,PDE4A,PFKFB2,PLEC,PTCH1,PLPPR1,PTN,RIPOR1,CEP97,BEND5,MYH14,ZNF821,CPEB3,SLC1A7,TMCC1,ATP10B,FCHO1,PLCB1,KAZN,TCF7L2,SZT2,CRTC1,HSPBP1,PLPPR2,FAM13C" Drug 4172_DN Fillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASIC1,LTBP4,MRTFA,AMPD3,MARK4,BRINP2,CFLAR,SYNJ1,SYNJ2,NEURL1,ASIC3,ZFYVE9,VAX2,WHRN,SNCAIP,PDE4DIP,GREB1,SRGAP3,ATN1,HIPK3,VPS13B,LRRC17,IGSF6,ZNF589,KIAA1109,CAMSAP1,GAD1,TMEM8B,SEPT9,RND1,GLYR1,RAB30,GPER1,ADAMTS13,GSN,SHISAL1,KCNMA1,KCNN1,VWA5A,NNAT,POLR2F,PPP2R2B,PRKCB,MAPK10,PTAFR,TCP11L1,SBF1,ASAP3,RPH3A,ARHGEF40,AP4E1,TRO,UCHL1" Drug 4784_UP Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ADRA1D,MRTFA,APBA2,APC,MARK4,BRINP2,ATP1A3,AZGP1,LDLRAD4,BTRC,CACNA1A,NEURL1,CDH18,FOXN3,PLEKHB1,TPP1,QKI,ARHGEF6,WHRN,CRMP1,VCAN,ARHGAP24,MFAP3L,PLXNC1,EIF4G2,RRAGB,DLC1,CAMKK2,DISC1,GART,GPD2,PCLO,ITIH2,KCNMA1,KCNN2,TAGLN3,NF1,NOVA2,OPCML,LRRN3,PRKAR1B,ENOX1,ZFHX4,EMID1,FRMPD1,SYBU,SLC1A7,SLC14A1,RIMS1,ZNF415,NEK4,FBXW11,ZNF45" Drug 4212_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ASIC1,CDC14B,CDK10,ASCL1,ATP2B3,CADM3,SYNJ1,CACNG1,MAP7,CHRNB2,SLC22A6,RAB26,HOMER3,WHRN,NCOR2,ARHGEF10,IPCEF1,PDE4DIP,TOX,RIMS3,EDN3,EFNB3,TENM1,COQ7,CORO2B,PDLIM5,GAB1,DISC1,MSTN,STON1,KLF12,HLF,ICA1,LAMA2,VWA5A,MEF2C,MMP16,PPARA,PPP2R2B,MAPK8,SUSD4,ROM1,SCN8A,SLC4A3,PREX2,SLC20A2,SNCA,KIF13A,DOCK9,SEZ6L,WNK1,ADAMTS9,EPM2A" Drug 7054_UP SB 202190; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-05 1.00E+00 4.41E-04 5.01E-03 53 196 "ABHD6,AP2A2,AK2,ADGRF5,APC,SYNJ1,ST3GAL5,GYG2,CAMK2G,ARHGEF1,CBFA2T2,MAGI1,FAM189A2,ARHGEF4,PPP6R2,RUBCN,ATN1,EDNRA,ZNF589,FGFR1,IQCG,OGA,B4GALNT1,AHDC1,MALT1,NR3C1,IL6ST,INPP5B,MAP4,MGAT3,NRGN,NLE1,SLC25A23,PLXNB1,GON4L,FAM184A,RGS12,SEC61A2,SBF1,SYBU,ABLIM3,ZNF365,PEX26,KIF13A,FCHO1,NCDN,MAPK8IP3,MCF2L,EXOC7,ZMYND8,ZKSCAN5,HPS4,SEMA3B" Drug 1643_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-05 1.00E+00 4.44E-04 5.05E-03 49 177 "OSBPL1A,BIN1,APP,CFLAR,ST3GAL5,CAMK2G,CNOT8,DNAJB5,CSF1,PDE4DIP,CTH,PUM1,EDRF1,NOS1AP,DBT,MFAP3L,RCAN1,MBNL2,ARMCX1,ZNF589,CAP2,SEMA4D,OGA,ERAP1,DISC1,MSL3,GNG4,DIDO1,NR3C1,GRM7,HMGCR,IL6R,MDM4,NAP1L2,OXTR,MBOAT7,MAPK8,HSPA4L,SH3BGR,FNDC3A,BTBD7,TSPYL2,SEMA4A,TRIM2,ZMYND8,VGF,PRDM2,FXR1,SENP7" Drug CID000092117 homocysteic acid Stitch 3.44E-05 1.00E+00 4.46E-04 5.07E-03 24 66 "DDO,CBS,SULT4A1,CNTN1,CTH,GPRASP1,F3,F5,SDCBP2,PCSK1N,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,NUCB1,OMG,SIRT2,TACR1,SIRT1" Drug CID000000942 Nicorette Stitch 3.60E-05 1.00E+00 4.66E-04 5.30E-03 118 529 "ASIC1,ACHE,ADORA1,ADORA2A,ADORA3,ADRB2,APP,BCHE,BMP7,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,RUNX1T1,CBS,LRBA,CHGA,ASIC3,CHRM1,CHRNA4,CHRNB2,CNR1,CNTFR,ACBD5,DBI,LYPD1,DMPK,DRD1,EDN1,EDN3,EDNRA,KCNMB2,F3,TUBB3,PPP1R1B,ACTL6B,NSG1,GABBR1,GABRA2,GABRA4,MYOZ2,MSTN,GFAP,GFRA1,GFRA2,LOXL3,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,HAPLN2,HMGB1,HMGCR,HTR2A,HTR5A,SCIN,IL6ST,IL12A,KCNC1,KCNH2,LIFR,MAOB,MAT2A,MMP16,MMP17,CCDC80,NODAL,NOS1,NPY,NTRK2,NTRK3,PDYN,PENK,PIK3C2A,PIK3CD,PIK3R1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,PSMD13,PBRM1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,FNDC3A,SLC6A1,SLC8A2,SCN3B,DDN,SST,TAC1,TAC3,LEFTY2,ACTR6,ZFP91,TTPA" Drug ctd:D008774 Methylphenidate CTD 3.67E-05 1.00E+00 4.74E-04 5.40E-03 39 131 "PNMA8B,RGS20,CHID1,CDK5R1,LARGE1,CHGA,CNR1,NCOR2,SNCAIP,SDC3,DAPK3,IP6K1,EXOG,DRD1,CNNM1,EPB41L1,GHDC,GRIK3,DHX35,KIFC3,NTRK2,SLC10A4,MAPK8,RET,SNX22,EPHA10,PEAR1,GALNT10,SORCS3,SNAP25,SOX11,NACAD,MLC1,ARC,AGTPBP1,CHST8,RGMA,STOX2,NETO2" Drug CID000656725 reactive blue 2 Stitch 3.70E-05 1.00E+00 4.78E-04 5.44E-03 29 87 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,APC,MIER1,CACNA1B,CACNA1E,P2RX6,ENTPD2,PLCXD3,SV2A,DMPK,ATP8A2,GFAP,HPGDS,LPAR4,PLCD4,AGFG1,P2RY13,NOS1,P2RX7,P2RY1,PLCB2,PLCD1,PLCB1,VIPR2,P2RY12" Drug 7211_UP Isoconazole [27523-40-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.71E-05 1.00E+00 4.79E-04 5.45E-03 51 187 "ARID1A,NDRG2,FZD9,ADORA2A,AK2,CDC42BPA,ATP1A3,NRP2,LDLRAD4,CA4,CAMK2G,CCKBR,MTMR7,CBFA2T2,CRY2,CSF1,NOS1AP,ST8SIA3,EDNRB,ST3GAL6,FGFR1,FYN,ZNF44,ALDH1L1,SRCAP,C1QL1,GLS,LILRA2,AP4S1,NEFM,NF1,NFYA,PDE3B,RETREG1,MTRF1L,PTHLH,ZSCAN32,ZSCAN2,ZMAT4,CCDC25,PKNOX2,BTBD7,ADGRL3,TRIM2,ZKSCAN5,FAM155A,WIPF1,ZFP37,DNALI1,KCNAB1,ITM2C" Drug 345_UP 2-propylpentanoic acid; Up 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Up 3.71E-05 1.00E+00 4.79E-04 5.45E-03 51 187 "ADD3,BIN1,AMT,BMP7,RAB29,BAIAP3,SPAG9,CBFA2T2,CHRM4,STOML1,ARHGEF10,PDE4DIP,GIT2,DNAJC6,JAKMIP2,EFNA3,MBNL2,CDKL3,EXTL2,TUBB4A,TAOK3,ZNF589,FGFR1,BAIAP2,C1orf61,FYN,CYP46A1,RAB40B,STON1,GRB10,KIF3A,KIF5C,TM6SF1,OMG,PDE4A,SERPINI1,PPP3CB,RAB3A,SH3GL3,ASAP3,SYBU,ZNF365,WDR47,FAM214B,SIRT2,ZCCHC24,AGTPBP1,TRIM2,AHCYL2,BEX4,RNF170" Drug 2344_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.71E-05 1.00E+00 4.79E-04 5.45E-03 51 187 "ADD3,GAS7,SEMA4G,MARK4,ST3GAL5,CACNB4,CAMK2G,CD86,CD38,RCBTB2,CHN2,SEC31B,CREM,ENTPD4,SIPA1L1,PPP1R16B,DOCK4,MFAP3L,TOM1,DYRK1A,CELSR3,LPAR6,HSD17B14,COQ7,ST3GAL6,BAIAP2,PDLIM5,INPP5K,LILRA2,SLC2A6,TJAP1,MYCN,ZNF862,OLR1,TREM2,PDE3B,CCSER2,PTPRE,BEND5,TCP11L1,FAM102A,ZKSCAN3,ZSWIM8,VAMP1,ARHGEF9,WSCD1,PSD3,TK2,SMUG1,TST,EMSY" Drug 4207_UP Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.71E-05 1.00E+00 4.79E-04 5.45E-03 51 187 "DPF1,ACTN2,ADRA1D,MRTFA,CDC14B,CDK13,MAP7,SYNGR3,ARHGEF2,MAGI1,JAM2,TPP1,DNAJB5,HOMER3,AKAP5,IFFO1,FEZ1,PDE4DIP,EDIL3,HIPK3,EFNA3,ING4,PLEKHO1,IGSF6,PDLIM5,CSPG5,DISC1,ADAM28,RAB30,HLF,KCNK1,CTNNA3,LYRM9,NF1,NPR2,MTRF1L,PPARA,PPP2R2B,MAPK8,PRPH,RGS4,ZFP2,NTNG1,PKNOX2,SLC11A1,DOK5,SOX15,DICER1,UCHL1,PARP6,KCNAB1" Drug CID000126756 LY 300164 Stitch 3.75E-05 1.00E+00 4.84E-04 5.51E-03 18 43 "ADORA2A,SV2A,STX2,FOLH1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3,KCNQ2,KCNQ3,LSS,ARHGAP9,ZFP91,EPM2A" Drug 2261_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "BIN1,APOC1,CDK13,ASPH,ADAM23,CACNG1,CLGN,TMEM59L,CNN3,CREB5,NCOR2,CNIH3,EDNRB,ING4,MTSS1L,PIPOX,DLC1,SCARA3,OGA,RUNDC3A,RND1,HPGDS,GLS,GPR22,GPER1,GRB10,GUCY1B1,ATXN2L,C2orf72,MX1,LRRN3,PRKAR1B,MAPK8,RAD52,C1orf54,RFX3,TTLL7,RYR1,SEMA6D,SELL,SH3BP2,ST6GAL1,PKNOX2,PDZD2,ZSWIM8,TCF4,TEX15,ICAM5,SEZ6L,CHST5,TUBB1,VLDLR" Drug 5967_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ADORA1,SEMA6A,BEGAIN,APC,HAP1,USP2,CACNA2D2,RCBTB2,LHX2,CLCN4,CNTFR,EDNRA,OPTN,EGR3,HSD17B14,DMTN,FYN,GABRA2,ALDH1L1,SRCAP,RND1,GLS,GNAO1,SPACA9,GRM1,HPSE2,IL6R,KCNJ9,KCNMA1,MEF2C,PDE1C,PMP2,PACSIN1,LRRN3,MAPK7,MAPK8,SAMD9,RASGRF1,MYH14,SALL1,LRRTM4,CNKSR2,ARHGAP26,RBM26,THSD1,ZC4H2,TK2,RIMBP2,TNS1,TRPM2,VIPR2,WIPF1" Drug 629_UP 2-propylpentanoic acid; Up 200; 1000uM; SKMEL5; HG-U133A Broad Institute CMAP Up 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ADD2,NME5,ALCAM,CDC42BPA,MARK4,ASPH,MTMR3,CA12,HIP1R,SPAG9,CDH10,WHRN,FEZ2,TNK2,DMTN,NRN1,SCML2,FGFR1,FHL1,ATP2C1,FYN,NEU3,PCDH17,FERMT2,TPPP,GRIK5,KCNH2,MARK1,MEF2C,GIT1,NFE2L2,NRGN,PDPK1,RETREG1,GPSM2,C11orf49,PPP3CA,PRKACB,RAB3A,RAB3IL1,ARID4A,RBBP6,SEC14L1,SMARCC2,CDK19,ST5,AHCYL2,SPX,ZMAT3,CADM1,RPRM,SLC17A7" Drug 5955_UP estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ADCY6,ALK,BEGAIN,ASPH,CFLAR,SCAPER,SGCE,BAIAP3,BTRC,CBFA2T2,SCARB1,ADGRG1,QKI,RCHY1,SH2B1,LRIG1,TBC1D5,C2CD2L,ATN1,DTNA,ST8SIA3,EGR3,STX2,ERCC2,FABP7,ATP8A1,ZNF589,FHL1,POLL,GPD2,GPM6B,NR3C1,MAP4,ZNF862,NF1,NUMA1,PIK3CD,RELN,RAB3A,RASGRF1,ZDHHC14,SLA,SLC2A5,SLC44A1,CHST5,TRIO,UCHL1,VAV2,LAT2,ZNF24,WNK1,MVB12B" Drug 6728_UP Betamethasone [378-44-9]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ADORA2A,ALK,CACNG1,SCARB1,CDH8,CACNA2D2,FOXN3,CHGA,CNTNAP2,CTNND2,FAM131B,MFAP3L,MAGI2,DRD1,HIPK3,ETV1,FGF12,FOXG1,DCTN2,CAMKK2,OGA,GAB1,GATM,ALDH1L1,C1QL1,RUNDC3A,GNAL,PRUNE2,GPR17,ELOVL5,IL6R,MATN3,MDFI,KITLG,AFDN,ADAM22,MX1,MYO7A,TMEM231,ZMAT4,RGS12,SLA,SLC1A7,SLC11A1,TNIK,ZHX3,ZC3H13,SPTAN1,GPR161,TK2,NAV2,PARP11" Drug 6054_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ASIC1,ARID1A,SEMA7A,KCNAB2,ARHGDIG,ALDH4A1,GYG2,USP2,SEPT7,CNTFR,FEZ1,MFAP3L,DTNA,HIPK3,EFNB3,C1orf61,PDLIM5,HBS1L,COPS8,RAB30,MSL3,CNTRL,GRIK5,IL6ST,KCNN2,KIF5C,MAP4,MMP16,MSI1,ADAM22,NEK1,CNOT4,NUMA1,PCDH9,PTCH1,RAD52,RNASEL,ZFHX4,TCP11L1,MAPK8IP3,PHLDB1,AJAP1,TRIM2,PSD3,TNS2,CRTC1,PCDHA6,TIAM1,TK2,TPD52,REEP1,PRDM2" Drug 6438_DN 5707885; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ASIC1,C1QTNF1,APBB2,ATP6V0A1,BCL7A,CFLAR,COL9A3,CSNK1E,KIAA0513,SMG7,DLG3,ELN,TUBB4A,FYB1,TRAF3IP2,ALDH1L1,SRCAP,GPER1,GRK4,SYNPO,SHISAL1,ITPKA,MAPT,NDP,NFIX,PDE1C,PDE4A,ENPP2,MED1,FAM120C,SH3TC2,MCMBP,TMEM156,SLC1A3,KBTBD4,TNIK,EMC1,CAND2,HECW1,ST5,MAPK8IP3,JMJD6,COBL,KAZN,TCF4,TRPC3,HIRA,CADM1,TRIM9,NDRG4,REEP1,NAV3" Drug 6188_DN clozapine; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "ASIC1,GRAMD1B,MTUS1,FAM131A,SEMA4G,ZSCAN18,BMP7,SCAPER,SLC25A14,ZFYVE9,PLAA,BAG4,CRY2,OSBPL3,PPP1R16B,EDRF1,GSDME,COQ7,CDKL3,SRCAP,GNG3,MAN1B1,ATXN2L,IL11RA,VWA5A,MYO7A,NUMA1,P2RY1,CDIP1,PILRA,PTPA,RAB3A,RALGDS,SEC14L1,MRAS,SLC11A1,TSPYL2,TCF7L2,SZT2,AP4E1,THBS4,PARD3,TPM1,ZKSCAN5,FLRT2,PLPPR2,VIPR2,ATP6V0E2,REEP1,MAP3K12,GDPD5,PCBP4" Drug 1517_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.83E-05 1.00E+00 4.94E-04 5.62E-03 52 192 "CDC14B,ATM,CFLAR,CAMK2G,KRIT1,CCNT1,CLCN3,DCAF8,DBT,DTNA,CNNM1,IRAK4,DENND4A,VPS26C,NOP56,FAM49B,GNG4,GPR37,KTN1,MMP16,NAP1L1,NFYA,SLC11A2,PDE3B,PIK3R1,MBOAT7,SIDT1,RIPOR1,ARID4A,RNASEL,NEK11,FOXRED2,SUPT20H,ZNF430,SON,EMC1,ZBTB43,POGZ,CEP68,TACC1,WWC1,PSD3,AHCYL2,TRIO,ZMYND8,RPRM,VGF,ZNF74,UPF3A,EVI5,FIP1L1,JMJD1C" Drug CID005039877 sym 2206 Stitch 3.90E-05 1.00E+00 4.99E-04 5.67E-03 8 11 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3" Drug DB00599 Thiopental Drug Bank 3.90E-05 1.00E+00 4.99E-04 5.67E-03 8 11 "CHRNA4,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GRIA2,GRIK2" Drug CID000032348 BPD I Stitch 3.90E-05 1.00E+00 4.99E-04 5.67E-03 8 11 "ARHGDIG,CANX,DNM1,SNAP25,SNCA,SYP,TF,PDIA2" Drug 2558_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASIC1,BIN1,APC,CDK13,PDE8B,C5,CACNB2,CAMK2G,NMT2,HOMER3,CPS1,CREM,CTIF,DNM2,EEF1A2,CELSR3,SUGP2,BSCL2,MTSS1L,DLC1,EFCAB2,OGA,SEPT9,POLL,SPACA9,GRM1,IL11RA,LSS,AFDN,ZNF862,SETD4,ENPP2,PLEC,GON4L,RAB3A,SEC14L1,MRAS,SH3BP2,ITSN1,CNKSR2,DBNDD2,SPTAN1,NCDN,VAMP1,PDLIM2,WWC1,DMXL2,TCF7,CHST8,KCTD2,TNNT1,REEP1,FAM13C" Drug 6412_UP CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "KDM5D,ADORA1,AMPD3,AMPH,OGT,GAS7,APP,CDK13,SYNJ2,NCOR2,CSF1,CYBB,SNPH,SV2B,TRAPPC9,HIPK3,ERCC2,PIPOX,FGFR3,RASL10A,GAB1,GAP43,ATP8A2,MSL3,NR3C1,INPP5B,ITGA7,MOBP,NOVA2,TREM2,PLCD1,PRKCB,GDPD2,PTCH1,CCDC40,RGS12,KCTD17,TMEM206,HUNK,SCN8A,SH3BP2,FNDC3A,SLC1A7,SHANK2,SLN,OGDHL,SPTAN1,PHLDB1,TNS1,TRIO,VIPR2,SLC13A3,CAMK1G" Drug 4319_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "CDK10,ADAM15,FUBP1,KALRN,HAP1,NEURL1,LARGE1,DZIP3,TBC1D5,RIMS3,SPOCK3,DLG3,EDN1,HIPK3,TUBD1,EPB41L2,EZH1,KAT8,FHL1,DPYSL4,GPR19,GPER1,GRK4,GRM7,SHISAL1,KITLG,OPRL1,PAK3,PALM,PDE2A,PFKFB4,TNPO2,PTPRN2,GAL3ST4,TTLL7,FBXW7,FOXRED2,ATXN7,ZNF821,SLC12A4,ELMO2,ZNF667,IQSEC2,ATP11A,SZT2,CRTC1,SMUG1,TRPC1,UBE3A,XRCC4,ZNF24,NDRG4,PHTF2" Drug 7258_UP Aminocaproic acid [60-32-2]; Up 200; 30.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "AMH,APC,MARCH3,SLC4A4,ALDH7A1,MTMR9,CFLAR,CACNA1G,MYRF,LDLRAD4,MAP7,SCARB1,NRXN3,VCAN,DZIP3,TBC1D5,SMG7,DPH1,MTSS1L,ANKMY1,ST3GAL6,FYB1,TMEM8B,CRCP,GLI2,ATXN2L,ITIH2,KCNJ5,KIF5C,MITF,CLDN11,PALM,PRKAB2,PRKAR1B,TMEM231,GTDC1,SUGCT,KIRREL1,RXRA,MAPK12,MYH15,TMCC1,SPTAN1,ARC,RPGRIP1L,SZT2,TK2,CABIN1,TRH,WNT7A,NUP214,ACTR3B,IFT88" Drug 3865_DN Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "RALGAPA1,CDC42BPA,APC,APP,MARK4,GYG2,TAOK2,TPP1,SH2B1,CSF1,SIPA1L1,SDC3,RABGAP1L,DTNA,HIPK3,SIDT2,EIF4G1,HSD17B14,ENO2,FGFR1,FHL1,CGREF1,GAB1,HBS1L,SYT17,SRCAP,GLYR1,GPD2,KIF5C,LSS,ADAM22,NEK1,NPR2,PPP5C,MAPK8,ENOX1,RGS12,CCDC25,ASAP3,ZNF365,CDK19,PLCB1,EXOC7,KIAA0930,TRIM2,WASHC4,TMOD1,TRIO,LAT2,KCNK12,SNX27,PHTF2,RNF146" Drug 5866_UP Estriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ABAT,ADD2,GAS7,CACNA2D1,MAP7,CDC42,SLC24A2,ARHGEF10,VCAN,PDE4DIP,SPOCK2,CTIF,CNIH3,MFAP3L,DLG3,DNAH9,TOM1,MBNL2,AASS,LRRC17,TDRKH,LILRA2,LPAR4,GPR37,KCNF1,KCNJ3,MMP16,MX1,NF1,PFKFB2,NLE1,PLCD1,MAPK7,PID1,GAL3ST4,RFX2,CARF,NEK11,SELL,FRMPD1,SLC4A3,FAM214B,SLC11A1,ELMO2,SLCO1A2,RBM34,CEP68,THRA,R3HDM1,TRPC1,HPS4,FAM13C,DPF3" Drug 7521_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "SEMA6A,CDC42BPA,ANK3,APC,GAS7,BCAS1,ARRB1,EIF4G3,KIF1A,ST3GAL5,CFAP410,CAMK2B,RUNX1T1,SYNGR3,ARHGAP33,CDH18,TPP1,NMT2,COL9A3,AKAP12,ABCG1,ATRNL1,CTH,GIT2,DMTN,CRCP,GLYR1,GRB10,DHX35,ADAM22,PDE3B,EPN1,SLC25A23,RAB3A,RAD52,RFX2,RGS3,RGS10,GSTCD,SLC22A4,ZC3H13,ARHGAP26,TSPYL2,NXT2,INKA2,MAPK8IP3,SZT2,ZNF34,TNR,TRIO,SPHK2,TFIP11,FIP1L1" Drug 3098_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,ABHD6,APBB2,AQP4,ALDH4A1,CDK5R2,INA,RAB33A,CNTN1,CREM,AATK,EDRF1,C2CD2L,HS3ST2,ELAVL3,PRELID3A,GPM6B,GRM1,ELOVL5,HNMT,KCNJ5,KHK,MGAT3,PFKFB4,PLCD1,PURG,PSD,CCDC40,RAD52,RFX2,ZFHX4,MYH14,KLHDC8A,MAP6D1,SH3BGR,ST6GAL1,SLC1A6,KANSL3,SLC6A11,PALLD,RBM34,WDTC1,TSNAXIP1,SOX10,SOX15,ARHGAP26,LHPP,MAPK8IP3,TRH,FAM155A,LMF1,SLC30A3,SLC17A7" Drug 3225_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NDRG2,CACNA1G,CFAP410,SEPT7,CDH2,ARHGAP33,CHN2,FAM189A2,QKI,COL9A3,RCHY1,RIMS2,EDRF1,MFAP3L,TENM1,VPS13B,PIPOX,REEP2,PTK2B,PRELID3A,GAB1,SYT17,RUNDC3A,GNG4,ATF7,GRM3,KLF12,INPP5B,KCNN1,MAP4,MMP17,GPR85,PPP2R2B,PPP5C,TMEM231,GTDC1,CPEB3,FAM214B,ZNF334,SLN,KIF21B,ZHX3,EMC1,ARHGAP26,KIAA1107,WSCD1,TCF4,DOCK9,PSD3,TRPC1,DNALI1,ADAMTSL3,SSPN" Drug 1682_UP Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ABHD6,APBA2,APBB2,APC,GAS7,BCAS1,APP,BCL2L2,SYNJ2,CFAP410,RAB33A,ZFYVE9,HOMER3,PICK1,NECTIN3,PDE4DIP,CYBB,RABGAP1L,DMPK,FEM1B,EIF4G2,BAIAP2,FOXG1,C1QL1,INPP5B,KCNB1,MAP4,NF1,NFYA,CNOT4,PALM,CDK18,KCTD15,PLCD1,PMP22,MAPK8,CCDC40,TRIM68,EMID1,FNDC3A,PKNOX2,SLC15A2,KDM4C,JMJD6,SMG6,AHCYL2,TMOD1,KAT6B,ZKSCAN5,VIPR2,REEP1,WNK1,KCNAB1" Drug 2260_DN Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "RALGAPA1,ASIC1,ADRA1D,AMPD3,BIN1,CDC42BPA,APBB2,GAS7,PLA2G4C,CFLAR,SPAG9,CDC27,CACNA2D2,FOXN3,NMT2,GREB1,JAKMIP2,SMG7,ATN1,TSPAN5,SIDT2,EFNB3,PLXNC1,FAM49B,GNG4,GPD2,SPACA9,GRIK5,HNMT,IGSF1,IL6ST,MAP4,MAPT,TM6SF1,MYT1,NUMA1,STRN3,PRODH,RAB3A,BCAN,LIMCH1,INKA2,PLCB1,EHBP1,PSD3,CRTC1,TK2,ZMYND8,ZIC3,REEP1,SLC30A3,WNK1,KCNAB1" Drug 6475_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NDRG2,ADCY6,ADGRF5,KCNAB2,PPFIA3,PRX,CDK13,N4BP2L1,AZGP1,KSR1,SGCE,RUNX1T1,RAB33A,KIAA1549L,CLCN4,FADS2,QKI,TENM4,CTIF,SRGAP3,EDN3,DLC1,FGF1,FGF13,ANKFY1,NSG1,GAD2,C1QL1,GUCY1A2,SCRG1,DHX35,ICA1,KIT,NEFM,NF1,CNOT4,PFKFB2,PLXNB1,POLG,C1orf54,GSTCD,FAM214B,PDZD2,KIF21B,ARHGAP26,ACSBG1,TEK,AP4E1,TLR4,TMOD1,TPM1,NSD2,MKRN3" Drug 2898_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "PLA2G6,CDK10,GYG2,CACNA1I,CACNG1,CAMK2G,CDC42,CDH10,EPS15L1,RAB33A,TCEAL2,SIPA1L1,CNTNAP2,RIMS3,ATN1,EDN1,EGFR,ANKMY1,BAIAP2,OGA,GAD1,SYT17,SRCAP,GNG3,GPER1,NR3C1,GRM1,ICA1,KIT,NUMA1,CLDN11,PFKFB2,SERPINE2,PRKAR1B,RALGDS,FAT4,GAL3ST4,KCTD17,KCNIP1,SALL1,RASA3,DOCK10,BTBD7,SLC22A4,ARFGAP1,LIMCH1,KDM4B,VAMP1,ARC,ATP11A,ZEB1,DOCK9,SLC30A3" Drug 3627_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "SYN3,ADD2,MRTFA,AMPD3,GYG2,CFAP410,CACNA1D,INA,CDH2,CHRM4,SULT4A1,SLC4A7,VCAN,RIMS2,TOX,SPOCK2,CTIF,DCT,GSDME,DYRK1A,EGR3,FGF14,FHL1,CAMKK2,KHDRBS3,CSPG5,GAD2,ATP8A2,RND1,HPGDS,GNAL,C2orf72,KIF5A,MGAT3,CD200,MYO7A,NF1,NLGN3,ELOVL2,PTPRO,ZMAT4,STUM,SH3GL3,DZIP1,PKNOX2,SLC11A1,IZUMO4,HECW1,SYN2,TMOD1,FLRT2,BEST1,SLC30A4" Drug 2992_DN Roxithromycin [80214-83-1]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "APBB2,RIPK1,CFLAR,KSR1,CACNA1A,CACNB4,SLC16A4,SCARB1,SOCS6,CHRNA4,B4GALT6,RUBCN,DBT,KIAA0753,TOM1,DYRK1A,E2F5,PLXNC1,C3orf18,ST3GAL6,ZNF589,EFCAB2,CAMKK2,GRK4,GRM1,NCKAP1L,ELOVL5,ICA1,LSS,MAP4,GIT1,NINJ2,SERPINE2,PLEC,PMS2,SIDT1,PTCH1,RAD52,RGS3,TCP11L1,CLIP1,FRMPD1,ARFGAP1,SNAP25,MAPK8IP3,ATP11A,EXOC7,TBL1X,TCF4,ARHGEF12,AHCYL2,R3HDM1,REEP1" Drug 5770_DN Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "APLP1,CDC14B,SYNJ2,SCAPER,C5,CAMK2B,NMT2,DZIP3,SDC3,ARHGEF4,DCAF4,GPRASP1,DCAF8,SPATA2,CNIH3,RUSC2,SIDT2,FGFR1,ANKFY1,FAM49B,TRAF3IP2,DISC1,SRCAP,C1QL1,ZNF276,TJAP1,MATN3,NPR2,PAK3,TMEM231,RAP1GAP,GSTCD,FBXW7,PAQR6,BTBD7,SMARCD3,SPTAN1,ZBTB43,COLGALT2,THSD1,ELOVL4,SYT1,ATP11A,IQCE,ARHGEF12,TRPC1,HIRA,NPDC1,XRCC4,NDRG4,NT5M,VPS35L,KAT6A" Drug 2361_UP Indapamide [26807-65-8]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MTUS1,SEMA6A,MRTFA,AQP4,CDK13,MARK4,BMP7,BAIAP3,LDLRAD4,INA,ZFYVE9,SLC4A7,SH2B1,VCAN,DAPK1,SIDT2,CAP2,ANKFY1,CELF1,DLL3,CHL1,GAD2,INPP5K,MYOZ2,LPAR4,KCNJ5,KHK,GIT1,MYCN,NELL2,NUMA1,OXTR,PFKFB2,ST8SIA5,MTRF1L,RALGDS,MYH14,FRMPD1,ANKRD6,SLC1A7,PKNOX2,SLCO1A2,TMCC1,ZCCHC24,KDM4C,ATP10B,SS18,SYN2,EXOC7,CDK20,VLDLR,EVI5,SSPN" Drug 483_DN Gleevec; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "KDM5D,NDRG2,MTUS1,KCNAB2,PDE8B,MPDZ,BMPR1B,CACNA1I,CA12,CD86,NDST3,LHX2,CLCN4,SH2B1,PDE4DIP,DCC,KLHL3,SIDT2,EFNA3,RCAN2,CORO2B,FCGRT,VSIG4,IRF8,KCNK2,MAN2A2,MGAT3,MYO6,PFKFB4,PLXNB1,C19orf57,PTPRD,PTPRN2,MARCH1,RET,ZNF671,RXRG,ASAP3,SLC1A3,EMC1,EXOC7,TMEM151B,TNS2,CRTC1,ZMAT3,SEZ6L,ZNF142,MAP3K12,GDPD5,STMN4,SLC17A7,MPPE1,MVB12B" Drug 5843_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ADGRF5,MRTFA,APBB2,SEMA4G,ATP2B2,ATP2B3,BAIAP3,SEPT7,SLC4A7,HAPLN1,NCOR1,PDE4DIP,DCAF8,GIT2,RBM12,TUBD1,KAT8,PNMA2,ERAP1,GLRB,MSL3,GNAO1,GPD2,GPER1,GRK4,GRIK5,NR3C1,ARHGAP12,MAPT,MIA2,TAGLN3,MX1,CNOT4,NTRK2,ODF2,NLE1,TNPO2,RAD52,GSTCD,KCNIP1,TRAPPC13,MRAS,SLC14A1,TMCC1,ZBTB43,SYN2,TBCEL,TIMP4,TNS1,RUNDC3B,HIRA,PLSCR4,EPM2A" Drug 1781_UP Demecarium bromide [56-94-0]; Up 200; 5.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ARID1A,ALCAM,AMT,APAF1,ASPH,N4BP2L1,PTBP2,INA,LRBA,ZFYVE9,CLTB,COL9A2,ECE2,DOCK4,ZBTB24,EEF1A2,FEM1B,SUGP2,ERCC2,VPS26C,ZMYND10,CAP2,TRMO,POMT1,GAD2,GAP43,ADAMTS13,PADI2,SCAMP5,AFF1,NFYA,OGDH,OGG1,PAK3,RETREG2,DEF8,RNASEL,SUPT20H,NTNG1,FNDC3A,SLC11A1,SPART,MLC1,VPS13A,TAC3,FAM208A,OBSL1,KAT6B,TRPM2,ZKSCAN5,PLPPR2,LAMP5,URM1" Drug 5692_DN Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ALCAM,APOC1,PDE8B,KYAT1,NEURL1,PLAA,VAX2,AKAP7,ARHGEF10,NOS1AP,DAPK3,JAKMIP2,MFAP3L,RUSC2,DTNA,SIDT2,SORBS3,EPB41L1,LRRC23,STX2,FAM198B,KIAA1109,IQCG,TBR1,MSL3,INPP1,KCNF1,LSS,MAP4,MAPT,MATK,ADAM22,ZNF862,NF1,ODF2,PLXNB1,SNRK,TMEM104,WDR25,ELOVL2,ZSCAN32,RIPOR1,RAD51D,RAD52,RGS3,PAQR6,FOXRED2,SLC1A7,SLC15A2,LIMCH1,ASTN2,RPGRIP1L,RBFOX2" Drug 3829_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,APC,APP,ATM,SLC4A4,BCL7A,CAMK2G,CRLF1,CLU,FAM189A2,CSF1,CTNND2,MAML1,ZNF804A,MFAP3L,DTNA,DUSP9,CNNM1,ELN,PLEKHO1,GPR153,GFER,POLL,RNFT2,HNMT,ITPKB,KHK,NPR2,NRGN,SLC25A23,SMIM7,STRN3,MBOAT7,PTPRE,ZSCAN2,RGS10,RGS12,SBF1,SEC14L1,SLC6A8,SMARCD3,DOP1A,ZCCHC24,WWC1,ZNF34,TK2,TMOD1,TPM1,FAM155A,MICAL1,LMF1,SEMA3B,FIP1L1" Drug 5825_UP Ursolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASIC1,ATP1A3,NRP2,CDK5R1,CFAP410,CACNB2,CACNG1,LARGE1,CNOT8,IQCK,COL9A3,CREM,ARHGAP24,CTIF,BRINP1,GIT2,KIAA0753,CDON,DTNB,FCF1,OPTN,STX2,PNMA2,ERAP1,SYT17,ALDH1L1,POLL,GSTM5,KIF5A,KIF5C,LIG4,VWA5A,MAN2A2,NEK1,NOS1,NTRK2,PDE3B,PPP5C,RAD51D,FNDC3A,SLN,SNCA,TMCC1,TSNAXIP1,ZHX3,IQCE,DOCK9,AHCYL2,BEX4,VAV1,TFIP11,CIAPIN1,EPM2A" Drug 5744_DN Calycanthine [595-05-1]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASIC1,C1QTNF3,APBB2,APC,PPP4R4,CDK13,STX16,ALDH7A1,SCAPER,CDC42,LARGE1,CHN2,TPP1,SULT4A1,AKAP7,TCEAL2,VCAN,ARHGEF4,EDRF1,MFAP3L,TOM1,SIDT2,TENM1,STX2,ERCC2,PDLIM5,OGA,TRAF3IP2,SRCAP,GNG4,KCNH2,MAPT,MMP16,MX1,NUMA1,NLE1,RAB3A,CCDC40,SLC2A5,KDM4D,SLC14A1,ZNF415,SAMSN1,KIAA1107,CHST8,GPR161,CABIN1,XRCC4,ZNF32,ZNF74,TFIP11,WNK1,EVI5" Drug 6265_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NME5,C1QTNF1,BIN1,AMT,APBB2,ALDH7A1,CFLAR,EPS15L1,FAM169A,TBC1D5,JAKMIP2,RCAN1,EDNRA,EFNB3,MTSS1L,STX2,EXTL1,FGFR1,GNAO1,GNAS,SLC2A6,KCNJ3,MGAT3,MID1,MSI1,NEFM,NF1,NOS1,PLXNB1,ELOVL2,ROM1,RPS6KA2,EMID1,PAQR6,FOXRED2,FBXO11,SYBU,ZNF365,SLC1A7,EPN2,ZSWIM8,CAMTA2,PHLDB1,MCF2L,KIAA0930,PSD3,SLC44A1,PLPPR2,LMF1,WRN,NT5M,SCG2,SEMA3B" Drug 3818_DN U-62066 [87151-85-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,BEGAIN,AMT,SEMA7A,APP,SEMA4G,PPP4R4,NRP2,BMP7,MTMR3,BTRC,CACNB2,CBS,ARHGAP33,LARGE1,AKAP7,AKAP5,SH2B1,HAPLN1,CSF1,MICAL2,CTNND2,SPOCK3,SUGP2,NCALD,EZH1,SORBS1,GABRA2,KCNMB4,GNG3,EML4,ICA1,TAGLN3,PDE4B,SPATA6,POLG,WDR25,GSTCD,RPS6KA2,SLC1A7,PREX2,BTBD7,SNCA,ARHGAP26,SPTB,CABIN1,TNS1,TRIO,FLRT2,ZNF225,MVB12B,DPF3,GAN" Drug 2734_DN Clidinium bromide [3485-62-9]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MTUS1,APAF1,CASK,ATP6V0A1,CFLAR,SYNJ1,FUBP1,CFAP410,CLGN,TAOK2,CLCN4,QKI,CREM,DGKG,DBT,KIAA0753,EFNA3,CELSR3,COQ7,ZNF589,CAMSAP1,FHL1,CELF1,INPP5K,LILRA2,PADI2,LIG4,MAP4,MIA2,NFYA,OLR1,PDE4A,PLTP,POU6F1,MINDY2,PTCH1,TMEM231,RGS3,CARF,FBXW7,SCG5,SLC20A2,ATP11A,CAMSAP2,WWC1,TBL1X,PSD3,AHCYL2,KCTD2,UBTF,CLIP2,ZNF225,EMSY" Drug 6785_UP "Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NME5,SEMA4G,ALDH4A1,SLC4A4,BCL2L2,CFLAR,KSR1,CHRNB2,CNTFR,CNTN1,MICAL2,NOS1AP,HDAC4,RUSC2,EFNA3,EIF4G2,SCARA3,PDLIM5,GNAO1,GRIK5,GRM1,ITPKB,KCNJ5,LIG4,ADAM22,NEUROD1,NPTX1,PDE4A,LRP12,PACSIN1,ELOVL2,RAB3A,RGS10,RAVER2,TCP11L1,SH3BP2,ASAP3,BCAN,SLC2A5,PKNOX2,ARHGEF40,MAPKBP1,ZCCHC24,HECW1,TAL1,PSD3,HEY1,TK2,TNS1,VLDLR,GDPD5,SLC17A7,ITM2C" Drug 3363_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "LTBP4,MRTFA,OGT,APC,PDXK,RGS20,ASPH,CFAP410,CLGN,STOML1,HOMER3,CNTN1,WHRN,CTNND2,EDRF1,ZNF804A,HP1BP3,ATN1,EFNB3,ING4,CAMSAP1,FHL1,SEMA4D,CGREF1,OGA,SRCAP,CACFD1,BTN2A1,IL6ST,JAK2,KIT,MAPT,MPP2,ADAM22,NF1,NOS1,NPTX1,SLC11A2,PLCD1,RAB5B,RASA3,SH3BP2,PEX26,SOX3,EMC1,THSD1,ELOVL4,STX1A,TBCEL,RPGRIP1L,VAV2,NDRG4,EMSY" Drug 3338_DN "Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "KIDINS220,OSBPL1A,AK2,CDC42BPA,APC,CDC14B,NUMB,ATM,MPDZ,BCL7A,SCAPER,RAB28,STOML1,SIPA1L1,MFAP3L,DNM1,DTNA,SIDT2,SUGP2,IRAK4,INPP5K,MALT1,TXNL4A,CACFD1,MUM1,DIPK1A,INPP5B,KCNH2,KCNJ3,MBNL1,MIA2,ZNF862,NF1,NUMA1,PC,PDE3B,TMEM231,RALGDS,RNASEL,CCDC25,AP1AR,NUBPL,TMCC1,EMC1,ITPRID2,FAM168A,ASTN2,TCF7L2,ZNF34,VAV2,ZBTB14,REEP1,SMIM8" Drug 7201_DN Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ANK3,CDC14B,MARCH3,ATM,MPDZ,SYNJ2,ARHGEF1,CRLF1,TAOK2,CREM,LRIG1,GREB1,PPP6R2,C2CD2L,DNM2,FEM1B,EIF4G2,EXTL2,EZH1,POLR1B,FGFR1,FAM49B,CGREF1,OGA,FYN,GAA,CLASRP,RNFT2,MAP4,MITF,GIT1,NUMA1,PLEC,PPP3CC,TMEM104,RGS10,ARHGEF10L,SEC61A2,SH3BGR,SMTN,KDM4B,WDTC1,LHPP,TACC1,ANKRD12,SIN3B,TCF7L2,TP53BP1,ZMYND8,PLPPR2,VGF,TFIP11,GAN" Drug 3174_DN Vinpocetine [42971-09-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,ABHD6,ALCAM,TRMT9B,APBB2,APOC1,SEMA4G,ARHGAP5,ARRB2,MARK4,ATP6V0A1,RIPK1,SCAPER,MTMR2,CFAP410,KYAT1,ARHGEF1,CREM,PDE4DIP,CTH,CYBB,DNAJC6,VPS13B,COQ7,VPS26C,ANKMY1,FGFR1,USP19,HNMT,KHK,MEIS2,NFYA,CNOT4,CAMKV,RAB5B,SEC61A2,ZNF821,FUZ,KIF13A,SOX3,UNC5B,VAMP1,SEMA4A,MCF2L,PCDHA6,ZNF34,TK2,ZKSCAN5,MAP3K12,HPS4,MPPE1,EPM2A,IFT88" Drug 2562_UP Isocarboxazid [59-63-2]; Up 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "KIDINS220,APBB2,ATP1A3,KSR1,CACNA2D1,HIP1R,CD86,TMEM257,NEURL1,ZFYVE9,KIAA1549L,CLCN4,DNAJB5,NCOR2,CSNK1E,BRINP1,KLHL3,PARD6A,EFNA3,TBC1D16,ATP8A1,C1orf61,LYVE1,GNAS,GPR22,GSN,HRH3,MBNL1,MMP16,LYRM9,NAP1L2,NEK1,ABCB1,PKN2,WDR25,MARCH1,SUGCT,RYR1,SCN2B,ZNF821,RASA3,CCDC92,SLC9A5,SLC11A1,BTBD7,PALLD,TNIK,ZC3H13,PLCB1,RALYL,AHCYL2,PARD3,NT5M" Drug 6009_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NME5,LTBP4,MRTFA,APBB2,MARK4,ATP2B2,CFLAR,BAIAP3,CACNA1D,CBFA2T2,NEURL1,CDH2,CHI3L2,CHM,TAOK2,SLIT2,ARHGEF6,CNTFR,WHRN,RCHY1,NECTIN3,NCOR2,GREB1,ARHGAP24,GIT2,TMCC2,ABCC9,ELAVL4,C3orf18,FOXG1,POLL,PRRC2B,LMO1,PCDH9,RETREG1,PPARA,KCTD17,KLHDC8A,WLS,ZNF821,FBXO11,PPP4R3A,SLC22A4,LIMCH1,KIF13A,INKA2,ARC,KIAA0930,TNS2,CRTC1,AP4E1,TTPA,LAT2" Drug 3471_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ADORA2A,PLA2G6,C1QTNF3,LTBP4,KCNAB2,APOC1,ALDH7A1,CFLAR,CA4,CAMK2G,ARHGAP33,CLGN,CACNA2D2,SRSF11,CHM,ENTPD4,CSF1,MAML1,SPOCK2,CNIH3,GNE,DTNA,SIDT2,C3orf18,HPCAL4,FOXG1,ERAP1,NR3C1,GRM2,ICA1,KCNF1,TM6SF1,MDM4,MGAT3,MSI1,ZNF862,PLXNB1,MAPK7,RAB3IL1,TCP11L1,RYR1,SH3BP2,SHANK2,KDM4C,AJAP1,PLCB1,ARC,KIAA0930,DOCK9,CRTC1,TRIO,REEP1,EMSY" Drug 4266_UP Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "DPF1,NDRG2,KIDINS220,SYT13,APC,CDK13,ATP2B3,RGS11,BRSK2,KCNAB3,CLCN4,NCOR2,ARHGEF10,DGKB,ATN1,MRNIP,IGSF6,EFCAB2,NSG1,FYB1,SEPT9,ALDH1L1,PRUNE2,GRM8,HTR2A,HTR5A,KCND3,MAP2,CTNNA3,NCAM1,NEFM,PDGFRA,ENPP2,EPN1,PMP2,POU6F1,PPARA,PTAFR,PTPRN2,KHDRBS2,RET,PKNOX2,SLC11A1,KIF21B,ACSBG1,VAMP1,ATP11A,SZT2,TK2,TLR4,DAAM2,ZMYND8,EPM2A" Drug 6198_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "SEMA6A,APC,LGR5,PDE8B,NCOA1,FGF17,BTRC,CACNA2D2,CHI3L2,SULT4A1,FAM149A,SIPA1L1,DZIP3,DLG3,EDNRA,MBNL2,ANKMY1,REEP2,FGF12,KHDRBS3,GPR153,GAB1,GLS,GPD1,PCLO,GRM8,GSTM5,AP4S1,HAS2,MOBP,NNAT,NOS1,NPPA,NRCAM,SERPINI1,RETREG1,PURG,SEMA6D,SCG5,FAM102A,RIMS1,ZCCHC24,ZSWIM8,OBSL1,TEK,ATP13A2,TK2,TRIO,KCNE5,RPRM,UBE3A,PRDM2,NUP214" Drug 2638_DN Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "DOC2A,BIN1,APOC1,ST3GAL5,CAMK2B,PLEKHB1,EPS15L1,PLAA,SLC4A8,DTNA,FER,AGAP2,GPR153,SYT17,SRCAP,POLL,GOLGB1,CNTRL,BTN2A1,HNMT,JAK2,KCNJ3,LIG4,MAP4,MATK,NF1,NFYA,SETD4,ODF2,RETREG1,LRRC49,PTPRE,CEP97,ZDHHC14,ROM1,FOXRED2,ZNF821,SMTN,ELMO2,WDTC1,SOX3,CLASP2,ARHGEF9,ZNF34,TJP1,TK2,CABIN1,TRIO,VAV1,VGF,MICAL1,TFIP11,RNF146" Drug 3717_UP Heliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "DPF1,KIDINS220,SEMA7A,APAF1,APP,DNAH17,CADM3,SCAPER,FOXN3,CHM,CLCN4,PDE4DIP,CNTNAP2,RIMS3,DCT,SHANK1,RCAN1,ABCC9,SGK2,FCF1,EGFR,MBNL2,EPB41,ATP8A1,FGF1,NSG1,GAB1,GAD2,ALDH1L1,ADAM28,POLL,GNG3,GPD2,GPR19,ADAM22,NDP,NF1,PACSIN1,PKN2,RGS4,MYH14,NXT2,INKA2,ARC,FBXW11,ZEB1,RPGRIP1L,TPM3,TRIO,VAV1,PARP6,KAT6A,RNF146" Drug 3420_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "C1QTNF3,LTBP4,MRTFA,AMPD3,APOC1,CDC14B,ARHGDIG,ADAM15,CA12,CACNA2D2,B4GALT6,HOMER3,CREM,SNCAIP,DNM1,TRAPPC9,ING4,LRRC23,ZNF589,FHL1,HBS1L,GPER1,NR3C1,HSD17B1,TJAP1,INPP1,LMO2,KITLG,NEUROD1,PCDH9,SLC25A23,PRKAR1B,PTN,RAB3IL1,EMID1,SH3BP2,PREX2,FAM214B,SHANK2,KIF21B,DOK5,INKA2,POPDC3,EXOC7,KIAA1107,PSD3,CRTC1,CHST8,FAM155A,SLC30A3,ITM2C,EPM2A,KAT6A" Drug 6787_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "AP2A2,AK2,PPFIA3,ATM,SYNGR3,PLAA,CLCN3,TPP1,BAG4,FEZ1,ARHGEF10,GPRASP1,DCAF8,KIAA0586,MAML1,MFAP3L,OPTN,SORBS3,CDKL3,ANKMY1,EZH1,OGA,SRCAP,GLS,GPR37,MUM1,MPP2,NNAT,PCDH9,PDE3B,SSH1,NLE1,WDR25,RAD51D,RALGDS,ZCWPW1,ARHGEF10L,ROM1,SHANK2,ERC1,SPART,ARC,TBL1X,TCF7L2,TRIM2,AP4E1,PARD3,KLC2,GDPD5,SEMA3B,SSPN,AAAS,GAN" Drug 2892_DN Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "C1QTNF3,APC,MPDZ,CA12,NECTIN3,PPP6R2,NOS1AP,DAPK3,MFAP3L,C2CD2L,SLC12A6,EFNA3,SORBS3,F3,KAT8,FHL1,GPR153,B4GALNT1,MSL3,HNMT,HSD17B1,TJAP1,INPP5B,KCNH2,MITF,MMP16,MPP2,LYRM9,NF1,NTRK2,PLCD1,MAPK10,RAD52,ZDHHC14,RGS3,BCAN,EPN2,CXXC4,LIMCH1,RBM34,SPTAN1,TSPYL2,SPART,TROVE2,TTBK2,TCF7L2,CRTC1,ATP13A2,TK2,MICAL1,REEP1,DNALI1,RNF170" Drug 7459_UP Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "SYN3,ADRA1D,SLC2A11,BCL7A,SYNJ2,FUBP1,CALB2,CAMK2B,LHX2,RAB33A,STOML1,RCHY1,NCOR2,ABCG1,CYBB,RIMS3,DNAJC6,ERCC2,TUBB4A,FOXG1,C1orf61,OGA,ALDH1L1,POLL,TJAP1,MAP4,MIA2,ADAM22,PLCD1,PLXNB1,LRP12,MBOAT7,PPARA,MAPK8,WDR25,PTH1R,PTN,RAB3IL1,RAD52,PAQR6,ANKRD6,ZC3H13,ATP10B,INKA2,COBL,ATP11A,WWC1,TCF7L2,VLDLR,LAT2,ZNF24,ZNF45,ADAMTS9" Drug 2618_UP Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MARK4,ADGRB2,RGS11,FGF17,CA4,ARHGEF1,CDH8,MYRIP,HAPLN1,NCOR2,CHD5,NOS1AP,EDN1,KIAA1109,FLNC,PRELID3A,SIGLEC8,INPP5K,ALDH1L1,KCNB1,MEF2C,ADAM22,NCF2,NF1,PGAM2,PIK3CD,MBOAT7,POLG,MINDY2,SAMD9,PLPPR1,PTPRD,PEX5,CCDC40,SLC6A15,RGS12,KCTD17,KLHDC8A,FOXRED2,PREX2,KDM4B,CAND2,SPTAN1,NPAS3,JMJD6,VAMP1,SYT5,TGFBR3,AMOT,VAV2,WIPF1,NUP214,TIGD6" Drug 3292_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ABHD6,NME5,APBA2,SEMA4G,ASTN1,CADM3,CCKBR,CBFA2T2,FOXN3,CNTN1,BAG4,NOS1AP,HP1BP3,HIPK3,FOXG1,PRRC2B,JAK2,KCNJ4,LSS,MIA2,MID1,MOBP,NDUFA5,NPTX2,PENK,PLCD1,PPARA,MAPK8,RGS12,EMID1,FOXRED2,SBF1,ASAP3,SLC1A7,SNCA,KIF13A,WDTC1,TSNAXIP1,INKA2,AJAP1,KAZN,RPGRIP1L,SZT2,FAM189A1,AP4E1,TGFBR3,HEY1,TNS1,CDK20,TRPM2,KCNK12,SPHK2,DNALI1" Drug 6867_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ACTN2,KIAA1324,C1QTNF3,APOC1,CDK10,RGS11,NRP2,CDK5R1,SCAPER,FOXN3,NRXN3,CNTFR,AKAP7,AATK,CTH,ZFYVE16,SMG7,ACOT8,ST8SIA3,ETV1,AFF2,COPS8,TDRKH,GRM7,ATXN2L,KCNJ4,L1CAM,NPR2,CLDN11,PFKFB2,PIK3R1,SPATA6,FAM120C,TMEM231,CCDC40,NEK11,ZNF671,RPS6KA2,STUM,SH3BGR,KDM4D,ZNF667,KIF13A,IZUMO4,KDM4C,MAPK8IP3,KAZN,MCF2L,TIAM1,CDK20,ZMYND8,UGT8,PARP6" Drug 2300_DN Mebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "APBB2,APOC1,PPFIA3,NCOA1,CA4,TPP1,DNAJB5,NIPBL,ARMC8,CHD1L,CRY2,PDE4DIP,DCAF8,KIAA0586,DBN1,DBT,PHF20L1,EPB41L2,DENND4A,F3,TESK2,GALC,USP19,COPS8,SPACA9,HSF2,IGSF1,ITPKB,KCNJ3,KCNN2,MATK,TM6SF1,RIPOR1,ARID4A,SYBU,PPP4R3A,FAM214B,RCOR3,FNBP1,TROVE2,ELOVL4,SEPT8,VAMP1,PLCB1,EXOC7,IQCE,PCDHA6,METTL3,REEP1,GDPD5,HPS4,ZNF248,LAS1L" Drug 5840_UP Isoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "GAS7,APOC1,CDK10,ATP2B3,ALDH7A1,ST3GAL5,SCAPER,SOCS6,PLAA,AKAP7,AATK,GIT2,DBT,MRNIP,RGS17,STX2,ABCA8,DLC1,FER,FGFR1,FHL1,PDLIM5,TBR1,ERAP1,GLYR1,GRM1,HSF2,KIF2A,TAGLN3,CNOT4,ODF2,OMG,OPCML,PCDH9,ENPP2,PHKG1,LRP12,GON4L,FAM120C,CCDC40,NEK11,AMBRA1,FNDC3A,NLGN1,PPP4R3A,TMCC1,POGZ,ACSBG1,TRIM2,UBTF,WIPF1,TFIP11,PARP6" Drug 2779_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ACTN2,ADCY2,GAS7,AQP4,MARK4,ALDH4A1,KSR1,CACNA1I,KALRN,CAMK2B,ARHGAP33,AKAP6,NCOR2,CSNK1E,DCT,DYNC1I1,SHANK1,DUSP9,IGSF6,FGFR3,TBR1,HPGDS,GNG3,GRM1,HTR2A,TJAP1,MAP4,MEF2C,MID1,AFF1,MOBP,CDK18,PLTP,PPP2R2B,PPP5C,KLHL11,SH3BP2,FRMPD1,SMTN,SLCO1A2,CXXC4,SNCA,HECW1,SPP1,NPAS3,NCDN,MAPK8IP3,ACSBG1,KAZN,EXOC7,TBCEL,TNS1,TRH" Drug 6068_UP Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "DPF1,KDM5D,SEMA7A,PPFIA1,CDK10,ARHGDIG,BAIAP3,LDLRAD4,FOXN3,CHN2,CLTB,SULT4A1,CNN3,RASSF2,DGKG,MYEF2,KLHL3,SV2A,SRGAP3,EGR3,HSD17B14,DMTN,CEND1,CAMSAP1,PRUNE2,GRIK5,PTGDR2,ATXN2L,IL6R,KCNH2,KCNK2,KIF5A,MAOB,MN1,NPPA,P2RY1,PLCD1,MTRF1L,RET,RFX2,SYBU,SLC2A5,SLC8A2,SLC22A4,SNCA,HECW1,SPTAN1,SYT11,SMG6,TIMP4,UCHL1,SLC17A7,KCNAB1" Drug 4544_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,AP2A2,APC,SHROOM2,STX16,CDH10,RAB26,SIPA1L1,MFAP3L,PARD6A,DLG3,DYNC1I1,DPH1,SORBS3,ANKMY1,FGFR1,IQCG,ANKFY1,DENND2A,GLYR1,MSL3,GPD2,GPER1,GRK4,RNFT2,GUCY1B1,SHISAL1,SCAMP5,MMP16,NASP,NDP,PDGFRA,PLCD1,SLC25A23,PPP5C,CSRNP3,DOCK10,SLC1A3,TROVE2,SS18,IQCE,DOCK9,CRTC1,DNAH7,CABIN1,UGT8,PLPPR2,LMF1,NSD2,NDRG4,MAP3K12,HPS4,KCNAB1" Drug 6864_UP STOCK1N-28457; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NLGN4X,APBB2,CDK13,ALDH4A1,CACNA2D2,EPS15L1,IQCK,NCOR2,ABCG1,CTNND2,RIMS3,SMG7,RCAN1,SNX29,ING4,TNK2,OLIG2,LRRC23,CORO2B,GAP43,ALDH1L1,POLL,WIF1,JAK2,KIT,MX1,NF1,NFYA,NTRK3,ODF2,PBX1,DUSP26,NLE1,FSD1,PPP2R2B,MAPK7,WDR25,C1orf54,SEC61A2,PEX26,PPP4R3A,SLC11A1,BTBD7,CDK5RAP2,SNCA,ZNF415,DDN,SYNE1,TMEM121,BEX4,RIMBP2,LMF1,XRCC4" Drug 1635_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "AP2A2,CDC42BPA,APBB2,MARK4,SLC4A4,CFAP410,B4GALT6,HOMER3,SLC4A7,CREM,CSF1,CTH,DCAF8,RIMS3,GIT2,DPH1,CNNM1,EFNB3,EGR3,F3,TMEM164,ZNF276,POLL,GNG4,DHX35,LMO1,MGAT3,MIA2,NF1,PLXNB1,RELN,TMEM104,PTCH1,RET,ROBO1,CCDC25,RPS6KA2,SYBU,SHANK2,ZCCHC24,KDM4C,CLSTN2,TRIM2,PCDHA6,CHST8,HEY2,TRPC1,VGF,SPHK2,MAP3K12,PRDM2,SEMA3B,PHTF2" Drug 2858_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NDRG2,MRTFA,APBB2,GAS7,APLP1,PLA2G4C,PDE8B,ATM,SLC4A4,CFLAR,CACNA1I,LDLRAD4,BTRC,PTBP2,SPAG9,SYNGR3,FOXN3,CHRNB2,ZFYVE9,ARHGEF6,PICK1,CSF1,VCAN,DGKG,TMCC2,ATN1,SIDT2,SORBS3,ERCC2,FYB1,GAB1,TMEM8B,GCNT2,GNG4,GRM8,KCNH2,MAPT,MITF,MSR1,ZNF862,RAD51D,EMID1,KCNIP1,SOX3,ZNF423,SAMSN1,MAPK8IP3,HEY1,TK2,WBP2,CLIP2,LAT2,PRDM2" Drug 4138_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ATP1A2,CFAP410,CACNB2,CDH10,CHI3L2,CHRNB2,CLCN4,QKI,WHRN,CRY2,PLCH2,DAPK3,ATN1,EFNB3,AASS,GABRA2,ERAP1,GPM6A,GPR22,CNTRL,GSTM5,ICA1,KCNMA1,MX1,OMG,OPCML,CLDN11,PALM,SERPINE2,PACSIN1,VPS13C,ELOVL2,RAB3IL1,GSTCD,RPS6KA2,WLS,STUM,SH3BP2,FRMPD1,ST6GAL1,ARHGEF40,LIMCH1,USP33,CAND2,PHLDB1,SZT2,DOCK9,SLC35G2,HIF3A,TEK,RUNDC3B,TRPC1,SSPN" Drug 3937_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASIC1,AP2A2,BIN1,KCNAB2,PLA2G4C,MARK4,TAOK2,CLTB,CNTFR,AKAP7,SH2B1,CRMP1,ARHGEF4,DBN1,RUSC2,TRAPPC9,CDON,DRD1,ATN1,DUSP9,EFNB3,DMTN,PIPOX,ANKMY1,FGFR3,FHL1,KHDRBS3,HBS1L,TMEM8B,SEPT9,GPER1,ITPKB,KCNN1,MAOB,MAPT,AFF1,MSR1,NPY,SETD4,PDE1C,PPP5C,MAPK7,RIPOR1,SEMA6D,SOX2,PEG10,ARHGAP26,LHPP,ATP11A,TNS2,TMEM121,WIPF1,KCNAB1" Drug 3433_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "CDC7,AP2A2,PDXK,ARHGAP5,ATM,MTMR9,CFLAR,SCARB1,NMT2,STOML1,QKI,SLC4A7,CREM,CSNK1E,MED24,DLG3,ENO2,DENND4A,ATP2C1,SRCAP,FERMT2,MAN1B1,KIF5C,ADAM22,PC,PRKAR1B,CNNM2,TMEM104,GTDC1,SGK1,FAM102A,FBXO11,RCOR3,CLASP2,CAMTA2,NCDN,FAM168A,ARHGEF9,VPS13A,TACC1,MTCL1,MCF2L,EXOC7,NSD1,AHCYL2,TIAM1,KCTD2,WBP2,HIRA,ZNF45,MPPE1,MVB12B,SMIM8" Drug 2501_DN Tenoxicam [59804-37-4]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ABHD6,NDRG3,KIDINS220,DOC2A,TRMT9B,AMPD3,APBB2,PPP4R4,CAMK2B,RUNX1T1,REPS2,USP6NL,DYRK1A,EIF4G2,SORBS3,CDKL3,CEND1,DLC1,PRELID3A,CSPG5,GABRA2,GCNT2,HTATSF1,GRIK1,GRM1,NCKAP1L,MAP4,MID1,MYO7A,NFYA,NUMA1,SETD4,PFKFB2,MAPK7,BCAS3,PTCH1,RAB3A,GAL3ST4,MYH14,SH3BP2,FRMPD1,SLC11A1,BTBD7,SLCO1A2,TNIK,DOK5,TROVE2,CRTC1,HSPBP1,VAV2,LMF1,ZBTB16,UBE3B" Drug 5771_DN Fluorometholone [426-13-1]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MTUS1,ANK3,KCNAB2,SEMA4G,MARCH3,ASPH,NCOA1,ALDH4A1,ATM,SYNJ2,CHM,RAB28,NRG2,CPS1,CREM,CSF1R,VCAN,PDE4DIP,FAM169A,GIT2,DBT,SLC12A6,MBNL2,LPAR6,TNK2,STX2,F8,GART,MSL3,GPM6B,BTN2A1,RNFT2,GUCY1B1,HSF2,ZNF862,NEK1,NF1,MINDY2,PTHLH,PTPRN2,FAM184A,RGS4,RGS7,PPP1R9A,AMBRA1,BTBD7,SLC20A2,KDM4C,SSBP2,ZKSCAN5,HIRA,PLPPR2,MPPE1" Drug 5249_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ADORA1,KIDINS220,SPARCL1,KSR1,GPR37L1,CHRNA4,ABI3BP,SDC3,ARHGEF4,TMCC2,SGK2,ERCC2,DLC1,FHL1,GABRA2,ZNF44,NEU3,GFER,LYVE1,GLI2,POLL,LPAR4,GRM1,GRM8,TJAP1,KCNC1,ADAM22,NCAM1,NNAT,NOVA2,PMP2,PPARA,PROX1,KHDRBS2,SUGCT,ZNF821,NLGN1,RPH3A,SLC11A1,SNCA,MAPK8IP3,SYT11,SYN2,WSCD1,CABIN1,CHST5,TRH,VIPR2,ADAMTS9,SCG2,CAMK1G,TIGD6,JPH3" Drug 3724_UP Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ASPHD1,SEMA6A,LTBP4,EPB41L5,CDK10,DNAH17,ADAM23,CFAP410,CACNA1D,CACNG1,CAMK2B,CLCN4,FAM149A,RIMS2,CYBB,NTM,DTNA,ECM2,EDN1,EPHB1,NCALD,BAIAP2,FYB1,SRCAP,GFER,GPR19,GSTM5,AP4S1,KCNH2,ADAM22,NF1,PALM,PCDH9,PDE4D,PDGFRA,PFKFB4,PROX1,PTAFR,PTN,RAD52,CPEB3,SLC1A7,ZNF334,SLCO1A2,SCN3B,SYT5,CHST5,CADM1,UCHL1,FLRT2,ZIC3,REEP1,STMN4" Drug 5383_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ARID1A,AP2A2,PLA2G6,AMPD3,APBA2,APP,CDK13,ATP2B2,ADAM23,SYNJ2,CAMK2G,INA,NEURL1,CDC42,CLGN,CHN2,ZFYVE9,VAX2,ABI3BP,DBT,DMPK,COQ7,FER,FGF1,FHL1,FOXG1,ZMYND11,GNAO1,GNAS,GNG3,PCLO,RAPGEF1,GRIK2,KLF12,HTR5A,JAK2,MDFI,NF1,SLCO1C1,NOS1,OPRL1,PDE3B,PPP5C,PTN,PTX3,RGS4,ASAP3,CNKSR2,PLCB1,SYP,SMG6,ZNF34,TRH" Drug 5349_UP Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ABHD6,ACTN2,AP2A2,APOC1,CDC14B,GYG2,USP2,ADGRG1,TAOK2,ZFYVE9,QKI,SH2B1,SIPA1L1,PDE4DIP,GIT2,GNE,SIDT2,DMTN,F5,ZNF589,ATXN2L,ELOVL5,KCNJ3,MAP4,MDM4,MITF,AFF1,MPP2,GIT1,NRGN,PLCD1,TMEM104,PTN,NKAIN1,RGS10,SH3BP2,FAM214B,EFHD1,CXXC4,EMC1,UNC5B,ZBTB43,PHLDB1,MCF2L,TCF7,ARHGEF12,ZNF34,ZKSCAN5,SYNC,EVI5,GDPD5,HPS4,MPPE1" Drug 5664_UP Practolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ACTN2,NDRG2,AK2,SYNJ2,MTMR3,SGCE,LDLRAD4,CFAP410,CACNG1,HAP1,NRXN3,CNTFR,CNTNAP2,RIMS2,SPOCK3,DTNA,EDN1,ETV1,NRN1,FHL1,DCTN2,DPYSL4,KHDRBS3,FYB1,FYN,ARPP21,TDRKH,RAPGEF1,GRIK5,GSN,HLF,SHISAL1,ADAM22,MYT1,PTPRB,RAB3A,ZMAT4,KCNIP2,FRMPD1,SLC9A5,ZNF415,EMC1,TROVE2,AJAP1,PLCB1,DICER1,CHST8,TK2,CHST5,TRPC3,VLDLR,PARP11,SSPN" Drug 3857_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ARID1A,ADRA1D,AK2,ALCAM,AMH,GAS7,CDK10,MARK4,NUMB,ATM,GYG2,CFAP410,NECTIN3,AKAP12,CSF1,GREB1,RIMS2,FAM49B,CGREF1,ALDH1L1,GFER,GLS,GNG4,STON1,ADAM22,ZNF862,PDE3B,PRKAR1B,GON4L,SNRK,PTHLH,ZSCAN2,RAD52,ENOX1,ZDHHC14,TRIM68,GTDC1,SH3BP2,PREX2,SHANK2,SNCA,WDTC1,TSPYL2,VPS13A,KIAA1107,IQCE,BHLHB9,VIPR2,MICAL1,LAT2,KCNK12,MAP3K12,GDPD5" Drug 4679_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NME5,AMT,KCNAB2,ALDH7A1,SCAPER,LDLRAD4,CLCN4,SLC4A8,ARHGEF10,VCAN,DZIP3,DAPK3,ARMCX2,RABGAP1L,DLG3,DPH1,EDNRA,CNNM1,MTSS1L,CDKL3,AFF2,GAD1,POLL,TDRKH,CNTRL,ICA1,MDFI,TM6SF1,MEF2C,AFF1,NEUROD1,NF1,OPCML,PDE4D,STRN3,PPP2R5C,ZSCAN32,ZSCAN2,RGS4,ZFP30,FRMPD1,SOX2,UNC5B,SPTAN1,ZBTB43,DDN,LHPP,SYT11,AP4E1,THRA,TK2,NDRG4,KCNAB1" Drug 7038_DN Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "BRAP,KCNAB2,EPB41L5,PPFIA3,APP,MTMR2,ARHGEF2,CDH10,USP6NL,KIAA0586,GIT2,TRAPPC9,RBM12,EIF4G2,HSD17B14,ANKMY1,KAT8,FOXG1,INPP5K,TDRKH,RNFT2,DHX35,ADAM22,NCAM2,NEK1,NF1,NUCB1,NUMA1,PDE4A,APTX,RAB3A,RAD52,RPS6KA2,ITSN1,SLC6A8,SHANK2,ZHX3,EMC1,UNC5B,MAPK8IP3,STX1A,VAMP1,MCF2L,CHST8,CABIN1,CDK20,METTL3,CADM1,PLPPR2,VIPR2,ZNF142,TIGD6,SSPN" Drug 3184_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "NLGN4X,ANK1,PPFIA4,APAF1,CDC14B,ATP1A3,BACH1,ADGRB3,BCHE,HAP1,SLC16A4,ADGRG1,CHN2,B4GALT6,CLCN4,CPS1,HAPLN1,NCOR2,CSF1,RASSF2,LYPD1,DLG4,AASS,TNK2,FGFR1,C1QL1,HPGDS,GRIA1,GRM7,GUCY1A2,ITGA7,KCNB1,NEFM,NOVA2,PDE3B,GPR85,PLTP,PPP1R1A,PPP5C,PRODH,DCHS2,GAL3ST4,MRAS,SLCO1A2,MYT1L,SOX10,DOK5,TROVE2,ZEB1,SLC35G2,TRIO,UGT8,SCG2" Drug 6167_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ADRA1D,AP2A2,MTUS1,ANK2,APAF1,APOC1,SEMA4G,MARK4,ZSCAN18,KIF1A,CDO1,CHRNB2,HOMER3,CREM,SH2B1,CRY2,CTH,GSDME,DTNA,CELSR3,ELN,DLC1,FHL1,PRELID3A,GAA,ZMYND11,GNG3,PRUNE2,GRM7,SOX21,ICA1,IL6ST,MAP4,N6AMT1,ZNF862,PDE4D,BCAS3,WDR25,RAB3A,RPS6KA2,ST6GAL1,PREX2,EPN2,SIRT2,WDTC1,IQSEC2,DDN,FCHO1,TBCEL,TCF7L2,VAV2,VIPR2,MAP3K12" Drug 205_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MTUS1,SEMA6A,AQP6,CADM3,CACNA1I,BAIAP3,CCNT1,CBFA2T2,DNAJB5,LY86,HOMER3,IFFO1,CRMP1,NCOR2,ABCG1,ARHGAP24,DTNA,DUSP9,MBNL2,ING4,COQ7,NCALD,FGFR1,C1orf61,GAD2,ZNF638,GRIK1,GRIN1,ADAM22,NAP1L2,NRGN,NTRK3,NUMA1,ODF2,CAMKV,PLXNB1,MAPK3,CNNM2,GON4L,RNASE1,MAPK12,STUM,ABLIM3,SLC2A5,SLC9A5,ELMO2,SPART,EHBP1,KIAA0930,TCF7,DNAH7,SEZ6L,WIPF1" Drug 2308_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ADORA2A,BIN1,APBA2,EPB41L5,ALDH4A1,ATP2B2,ADGRB3,CFLAR,CAMK2B,CLGN,LHX2,ZFYVE9,CLU,AKAP7,FAM149A,AATK,TENM4,FBXL5,DTNA,EDNRA,HIPK3,EZH1,DLC1,ZNF589,OLFM1,FGFR1,SRCAP,CSDC2,RND1,GNAL,ICA1,IRF8,JAK2,KCNJ3,BCO1,SLCO1C1,NNAT,PAK3,LRP12,PACSIN1,RELN,GAL3ST4,SEC61A2,RPS6KA2,STUM,SLC1A7,SLC9A5,LIMCH1,SOX2,VPS13A,PARD3,TPM2,DPF3" Drug 314_UP sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "KDM5D,ADD2,LTBP4,OGT,ANK1,GAS7,CHRD,CADM3,AZGP1,BAIAP3,CFAP410,CAMK2A,CHRM4,B4GALT6,VCAN,PDE4DIP,RABGAP1L,DYRK1A,ING4,ELN,COQ7,STX2,NCALD,SPEG,FGR,TRMO,GABRB1,GFAP,RUNDC3A,GUCY1A1,ITPKB,KHK,NEK1,P2RX7,PIK3CD,FXYD1,STRN3,MAPK8,PTPRD,SUSD4,ATXN2,FRMPD1,ABLIM3,SLC6A9,KDM4B,NMNAT2,ZFR2,ATP11A,ADGRL3,GPR161,TRPC1,FLRT2,ZIC1" Drug 2356_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "MRTFA,AMH,BIN1,ANK2,APBB2,APOC1,CDK13,CAPRIN2,ALDH4A1,KIF1A,KSR1,CDK5R1,ARHGAP33,TAOK2,CREM,ZFYVE16,ZNF337,SPOCK2,EDNRA,SIDT2,CELSR3,MBNL2,RASGRP2,F5,FOXG1,ZNF44,WASF3,ZNF276,MSL3,GRM1,TM6SF1,MYH3,MYO6,PFKFB2,PLTP,PMP22,PRKCZ,RAD52,PNMA8A,ITSN1,FERMT1,SLC11A1,BTBD7,SNCA,KIF1B,VAMP1,KAZN,WSCD1,SIN3B,TCF7,TK2,ICAM5,DAAM2" Drug 2314_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "ARID1A,AMPD3,SEMA7A,MARK4,ATM,SCAPER,BAIAP3,HAP1,TAOK2,RAB33A,QKI,CRMP1,CSF1,KBTBD11,C3orf18,HSD17B14,LRRC23,ANKMY1,F3,ZNF589,FGFR1,ERAP1,SEPT9,GLYR1,SPACA9,GSN,ATXN2L,DHX35,IGSF1,KCNN2,ZNF862,PCDH9,CDK18,GSTCD,CCDC25,ROM1,EMID1,ZNF821,SH3BP2,BTBD7,IQSEC2,ZBTB43,PHLDB1,SYN2,TCF7L2,PCDHA6,ATP13A2,THRA,FLRT2,ZFP37,SYNC,EVI5,HPS4" Drug 2439_DN Menadione [58-27-5]; Down 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "CDC7,ADORA3,APOC1,APP,BARD1,LDLRAD4,ARHGAP33,CLGN,CLCN4,STOML1,ARHGEF10,SLITRK5,RHOBTB1,DTNA,RASGRP2,SYNCRIP,ERAP1,SEPT9,GLYR1,LILRA2,GPR19,KCNN2,NASP,NPR2,SLC11A2,NUMA1,SLC25A23,C11orf49,MAPK7,SIDT1,TMEM104,C1orf109,TTC13,GTDC1,RPS6KA2,LGR4,DGLUCY,ITSN1,SLC15A2,SLC20A2,KIF21B,ZSWIM8,ATP11A,DDHD2,WDR7,TK2,CBX5,TMPO,PARD3,TNS1,ZBTB14,HPS4,EPM2A" Drug 2282_DN Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "RBM10,LTBP4,MRTFA,DOC2A,GAS7,APOC1,FUBP1,SCAPER,HAP1,CAMK2G,FOXN3,AKAP7,SLC4A7,LRIG1,ARHGEF4,MAML1,C2CD2L,DLG3,LRRC23,FOXG1,GCNT2,SRCAP,POLL,IPO5,VWA5A,MMP16,NPR2,CDK18,PDE3B,PLCD1,SLC25A23,PPP5C,CNNM2,TMEM104,PTN,RAB3IL1,KLHDC8A,RPS6KA2,ANKRD6,ABLIM3,CXXC4,SMARCA4,SMARCD3,KIF13A,WDTC1,TSNAXIP1,CLSTN2,VAMP1,PLCB1,SZT2,PARD3,SPHK2,TIGD6" Drug 3119_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "SYN3,ABHD6,AP2A2,SYT13,CDC42BPA,APBB2,BCAS1,PRX,GYG2,HAP1,RUNX1T1,CLU,COL9A3,CRY2,PDE4DIP,ST18,PARD6A,SPOCK3,CDON,CELSR3,PLEKHA1,EIF1,CEND1,C1orf61,WASF3,GPR162,KCNMB4,SCIN,ITPKA,MAP4,MOBP,NTRK2,PFKFB4,PLCB2,NECAB2,POU6F1,CEP41,PRPH,PTPRN2,FAM120C,ENOX1,RASGRF1,MAP6D1,PKNOX2,PEG10,SYP,MTCL1,DNMBP,TBCEL,LMF1,SLC13A3,STMN4,KCNAB1" Drug 6890_UP AH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.95E-05 1.00E+00 4.99E-04 5.67E-03 53 197 "RALGAPA1,C1QTNF3,GAS7,APOC1,BCAS1,PPFIA3,ASPH,ATP1A2,SCAPER,CACNA1D,CLU,ARMC8,COL4A5,SPOCK3,DTNB,ST8SIA3,MBNL2,ING4,OLIG2,STX2,ERCC2,FGFR1,CGREF1,GLYR1,POLL,KCNMB4,CNTRL,PADI2,ATXN2L,ELOVL5,IRF8,KCNH2,SMAD1,MATK,ADAM22,MSR1,ZNF862,NDUFA5,NPY,PALM,PDE4A,PPARA,RAD52,ZFP30,COA1,KIF13A,TMCC1,KAZN,DMXL2,CADM1,CLDND1,SYNC,MPPE1" Drug CID000061672 orthovanadate Stitch 4.04E-05 1.00E+00 5.09E-04 5.79E-03 100 435 "ADCY5,ADCY6,ADCY8,KIF6,PDE8B,DNAH17,DYNLL1,ATP1A1,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,ALDH7A1,KIF1A,CACNA2D1,CALM1,RGN,AIFM1,ENTPD2,LRBA,ABCG2,DNAL1,DNAH9,DTNB,ABCC5,EGFR,ENPP6,ERBB4,PTK2B,FGF1,ACTL6B,ATP6V1H,ATP2C1,GCK,BRD8,MCHR1,GRM5,IGF1,JAK1,JAK2,KCNA2,KIF5A,MBP,KITLG,MYO7A,OLR1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PDGFRA,PFKFB4,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PTPA,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK10,PTK2,PTPN13,PTPRB,PTPRD,PTPRG,KIF7,RNASE1,GSTCD,RYR1,SBF1,KIF27,KIF16B,SLC14A1,KIF13A,KIF1B,SST,SSTR1,SSTR2,ABCC8,PLCB1,TAC1,ALG1,TF,ACTR6,KLC2,WNK1,PLD4" Drug CID000000222 ammonia Stitch 4.04E-05 1.00E+00 5.10E-04 5.80E-03 114 509 "ABAT,ADAR,BRAP,ALAD,AMPD2,AMPD3,AMT,DDO,NT5C3B,ALDH4A1,SLC4A4,BCHE,CACNA1B,CACNA1E,CBS,KYAT1,CD86,CPS1,GDA,CRYM,CS,CSF1,PITPNM3,CTH,BOC,EARS2,NTM,CHRDL1,MED12,ATN1,DTNB,TUBD1,ENO2,DMTN,ERCC2,PIPOX,GMPR2,PTK2B,TUBB3,TUBB4A,ACTL6B,PNMA2,CHL1,MTHFD2,DNER,TUBA8,BRD8,GLS,GLUL,LOXL3,GPD1,STON1,TUBA1C,GRIK1,GRIN2C,GRIN2D,CIT,PADI2,HRH3,NEGR1,IDH3A,TUBB2B,ITGAM,L1CAM,MAOB,MAPT,MAT2A,MSRA,NBL1,NCAM1,NCAM2,NOS1,OGDH,SNTG1,CNTN3,PC,PFKP,PKD1,PKM,PLEC,PMP2,PRODH,RAB3A,RAB3IL1,RDX,ACER3,S100B,ASRGL1,SHMT2,SLC1A2,SLC1A3,SLC4A3,SLC6A1,SLC14A1,SLC22A4,SP2,CLSTN2,SST,SYT1,PJA1,MLST8,THRA,TIE1,ACTR6,KAT6B,TNNT1,RBFOX2,NPL,TUBB2A,TUBB1,TUBA1A,SLC17A7,NELFE,GAN" Drug ctd:D001640 Bicuculline CTD 4.05E-05 1.00E+00 5.10E-04 5.81E-03 14 29 "MPDZ,NCOR2,GABRA1,GABRB1,GABRB3,GABRG1,GABRG2,GRIA1,GRIA2,GRIN2D,OXTR,MAPK3,RYR1,ARC" Drug CID000002789 clobazam Stitch 4.05E-05 1.00E+00 5.10E-04 5.81E-03 14 29 "DYNLL1,CACNA1B,CACNA1D,LGI1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PTCH1,SLC6A1,SLC6A11,ZEB1" Drug CID000129400 K-II Stitch 4.08E-05 1.00E+00 5.14E-04 5.84E-03 31 96 "ACHE,ALS2,BCHE,CACNA1B,CACNA1E,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,KRIT1,CDR1,NUMBL,DCTN1,DTNB,SORBS3,AGAP2,CNDP1,GRIA1,HNMT,MAPT,RAB3A,RBBP8,RPH3A,SNAP25,ADHFE1,SYN1,TAC1,TAC3,ATP13A2,NUP214" Drug CID000002833 colchine Stitch 4.10E-05 1.00E+00 5.16E-04 5.87E-03 90 383 "ACHE,AP1B1,INTS2,MAGEE2,FGF17,CFLAR,DST,BSN,CA4,CALB2,CALM1,CCK,AIFM1,CHRM1,CHRNA4,CHRNB2,ABCG2,CNTN1,COL4A5,COL9A1,COL9A2,COL9A3,COL11A2,VCAN,SDC3,BOC,TUBD1,STX2,CD320,PTK2B,TUBB3,TUBB4A,FGF1,FGF11,FGF12,FGF13,FGF14,ACTL6B,DCTN2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,TUBA8,GLRB,GPT2,TUBA1C,TNFAIP8L3,ATCAY,TUBB2B,LAMA2,STMN1,MAP2,MAPT,NOS1,NPY,CNTN3,PDYN,PENK,ABCB1,PIK3C2A,PKD1,LAMA1,PTK2,PTPRN,PTPRN2,PTX3,FNDC3A,SNAP25,PDZD2,SPP1,DDN,SST,STX1A,TBL1X,ACTR6,TNFRSF1B,TUBB2A,TUBB1,STMN4,TUBA1A,WNK3,NLRP3" Drug CID005287890 N-cyclopentyl-N-cyclobutylformamide Stitch 4.12E-05 1.00E+00 5.19E-04 5.90E-03 27 79 "AGT,BBS2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CBFA2T2,CACNA2D2,CHGB,CREM,CACNG7,CACNG2,ATP2C1,PKD1,GLDN,ACER3,RYR1,RYR3,SELL,SCG5,SMUG1" Drug CID003001858 Sistan Stitch 4.16E-05 1.00E+00 5.24E-04 5.96E-03 16 36 "MRTFA,CALB1,VCAN,CSPG5,ATP8A2,GRM3,GRM5,GRM7,ABCB1,MARCH1,SHANK2,CLSTN2,TAC1,TCEA1,SLC30A3,SLC17A6" Drug ctd:D014284 Triiodothyronine CTD 4.25E-05 1.00E+00 5.34E-04 6.08E-03 109 483 "ADD2,ADORA1,ADRB2,PLA2G6,BCAR3,AMH,APP,TMEFF1,ASPH,NCOA1,ATP2A2,ADAM15,HCN2,BMP7,CALB1,ARHGEF25,CBS,CCNH,ZBED1,SLC22A6,CLU,FADS2,TMEM184B,SULT4A1,IGLON5,FAM171B,AKAP12,NCOR1,NCOR2,CTH,HDAC9,ZNF337,DMPK,PLXNC1,DMTN,SLC43A2,ZNF461,TUBA1B,FDFT1,FGF1,FGFR1,FGFR3,MEX3B,POMT1,DLL3,GAP43,GATM,GCK,PPARGC1A,TTBK1,GLI2,RAB30,AIFM3,GRIK4,NR3C1,BTN2A1,MFSD2A,HBA1,MIER3,IGF1,PLD5,TUBB2B,ITGAM,KCNA1,KCNA4,LSS,MBP,ADAM11,ADAM22,LYRM9,MYH6,MYH7,NDUFA5,NEFM,NFIX,NKX2-2,NRGN,PCSK1,PCSK2,PFKP,PIK3CD,SMOX,POLG,PPARA,MAPK3,PEX5,DPF2,TMEM100,HUNK,WLS,RXRG,TRIM46,SHMT2,PAAF1,SLC1A2,SLC2A5,EPC1,PEG10,KIF1B,EPB41L3,TRIM2,SIRT1,THRA,HIRA,FLRT1,VLDLR,LGI4,NUP214,TIGD6" Drug ctd:D010795 Phthalic Acids CTD 4.28E-05 1.00E+00 5.39E-04 6.13E-03 162 770 "SYN3,ACTN2,PLEKHH1,ADRA1B,MTUS1,TBC1D14,CC2D2A,SRPX,BCAR3,ANXA7,CDC14B,CADPS,ZBTB10,STX16,ATP2B3,KIF1A,CDK5R2,CALB2,CANX,NFS1,CBLN1,SCARB1,MYOM2,CHRNA4,DLGAP3,NMT2,FADS2,CNN3,MYRIP,ZNF521,ABCG1,PDE4DIP,SLC45A1,CTNND2,RUBCN,DBI,ZC3H11A,SACS,FAM107B,DYNC1I1,DNM2,ABCC9,EDNRA,KLHL5,TMEM132E,KCTD3,EIF4G2,NCALD,MRPL37,ETV1,ACSL4,ST3GAL6,FDFT1,OLFM1,FGF13,BAIAP2,TMEM164,SORBS1,POMT1,NSG1,MPP6,OGA,GAA,AHCYL1,NCKAP1,CPLX2,GBX2,ALDH1L1,SESN1,GGT7,RNPS1,HPGDS,HTATSF1,GNG3,TDRKH,GRB10,RAPGEF1,GRIA4,GRIN1,ZNF496,ELOVL5,HMGCR,HP,ATCAY,ZNF385B,KIF2A,KIF5C,KIFC3,IPO5,LSS,PIK3AP1,GPR155,DBNL,MYBPC1,MYH6,MYO9A,NCAM1,NOS1,NPTX2,TBC1D25,ZDHHC22,TREM2,ETFRF1,PDYN,PFKFB3,ABCB1,ZNF655,RC3H2,POU3F4,DRAM2,PTPA,PPP3CB,TTC13,PID1,PLEKHB2,FAT4,RFX5,RGS12,CYB561D1,RORB,LGR4,WLS,SBF1,SCP2,ASRGL1,TRA2B,SGK1,KIF21A,ANKRD6,SLC1A6,SEPHS1,ATF7IP,CDK5RAP2,SMARCE1,FAM126B,SCN3B,SOX2,SOX10,STXBP1,VAMP1,AGTPBP1,KLHL4,NSD1,DICER1,TNS1,TPM1,TPM2,ZMYND8,TST,TTPA,FAM155A,PLEKHH2,VSNL1,ZIC3,ZNF142,ANKS1B,STOX2,WNK3,HRASLS,AMN1,IFT88,RNF146" Drug 5116_DN Mometasone furoate [83919-23-7]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.32E-05 1.00E+00 5.43E-04 6.18E-03 51 188 "ABR,MTUS1,ARRB2,MARK4,RIPK1,SYNJ2,VCAN,SOCS5,SLITRK5,SNPH,ARHGAP24,TMCC2,EDNRA,APH1A,LPAR6,ETV1,GAD1,B4GALNT1,DISC1,GLS,SHISAL1,IL11RA,MAPT,NDP,NF1,NUMA1,OGDH,PBX1,PPARA,SAMD9,CSRNP3,FAM102A,PPP1R9A,PEX26,SLC14A1,ZNF415,WDTC1,NCDN,PHLDB1,TBL1X,TCF4,KIAA0930,PSD3,ARHGEF12,ZMAT3,BEX4,PLPPR2,WNT7A,MAP3K12,MPPE1,AAAS" Drug 3241_UP Etoposide [33419-42-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.32E-05 1.00E+00 5.43E-04 6.18E-03 51 188 "ANK1,CDK13,STX16,CFLAR,BTRC,TCEAL2,NCOR2,RIMS2,KIAA0513,ARMCX2,EDNRA,ELAVL3,CDKL3,ZNF589,HBS1L,SIGLEC8,SRCAP,SESN1,POLL,IRAK3,KLF12,INPP1,INPP5B,ITIH2,KCNN1,MAN2A2,TAGLN3,TREM2,MTRF1L,PRODH,PTPRB,NKAIN1,RIT2,ZFHX4,CARF,TCP11L1,ZFP2,ASAP3,PEX26,SLC14A1,SLC22A4,MAPK8IP3,ACSBG1,ASTN2,ZEB1,PSD3,GPR161,ZMAT3,TMOD1,SLC30A4,DNALI1" Drug ctd:D007980 Levodopa CTD 4.33E-05 1.00E+00 5.44E-04 6.19E-03 33 105 "ADORA2A,ADRB2,APP,ARRB1,CALB2,DLG4,DPYSL2,DRD1,RASGRP1,PPP1R1B,GABRA1,GABRG2,GAD1,GAD2,GAP43,GRIA1,GRIN1,GRM1,GRM5,IDH3A,STMN1,MT3,SLC11A2,OPA1,PDYN,PENK,MAPK3,RASGRF1,ATXN2,SLC1A2,TRH,UCHL1,TUBA1A" Drug CID000016886 5-aza-2'-deoxycytidine Stitch 4.37E-05 1.00E+00 5.49E-04 6.24E-03 138 639 "ASIC2,NDRG2,BRAP,LRRC7,PCDH10,BIN1,APAF1,APBA2,APC,CCAR2,DYNLL1,ATP2A2,KIF1A,CFLAR,CDH2,CLGN,TJP2,AKAP12,NCOR1,LRRC3B,CMTM5,CTNND1,HDAC9,HDAC4,RASSF2,DAPK1,SCRN1,DAPK3,SPOCK2,BRINP1,MYEF2,GSDME,WDR20,HS3ST2,SHANK1,GNE,TOM1,ABCC5,E2F6,EDIL3,CNNM1,EFNA3,EFNB3,EBI3,EGFR,EMX2,TUBB3,TUBB4A,EFEMP1,DLC1,ST3GAL6,ZMYND10,FGF14,FOXG1,AFF2,SYT3,SORBS1,DKK3,IQGAP2,ZNF559,SEPT9,GBX2,GPR162,PRLHR,GRIA1,GRM5,GRM7,FAM107A,WIF1,HNRNPK,CPT1C,IRF8,IFI16,ITGAM,MAT2A,MBD1,MBP,LRP1B,MEF2C,MSRA,SAMD14,MX1,NELL1,NNAT,NOVA2,PAX6,ABCB1,FSD1,IRX1,PROX1,KLK6,PTCH1,PTPRG,RASGRF2,ARID4A,RFX5,ROBO1,ROBO2,EPHA10,RXRG,SMPD3,LIMS2,TMEM132D,SLIT1,SMARCC2,SNRPN,BEX1,SST,EPB41L3,LRRC4,ERBIN,SMG6,ZEB1,AZIN2,PSD3,SLC35G2,DICER1,HHIP,TSC1,TMEFF2,CADM1,RPRM,UBE3A,UCHL1,WNT7A,PCDH20,MKRN3,ZNF177,PMEPA1,PRDM2,PRTFDC1,SEMA3B,HRASLS,AMN1,FZD3,MSRB3,FXR1,AP3B2" Drug 6717_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ADRB2,KIDINS220,PPFIA4,KCNAB2,APC,GAS7,CDK13,CACNA2D1,ARHGAP33,QKI,VCAN,PDE4DIP,CTH,HDAC9,TOX,C2CD2L,ST8SIA3,SIDT2,MTSS1L,SCML2,AMOTL2,C1orf61,EFCAB2,SIGLEC8,ALDH1L1,LILRA2,GPR45,ATXN2L,ELOVL5,HPSE2,KCND3,KCNJ5,MX1,MYH3,NOVA2,NTRK2,OLR1,OMG,EPN1,LRRN3,PTPRH,PTX3,MARCH1,HKDC1,FAM214B,RAP1GAP2,VAMP1,SYT1,TAL1,RPGRIP1L,SEZ6L,JPH3" Drug 6734_DN Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ADRB2,BIN1,APP,CACNA1I,SOCS6,NRXN3,NMT2,DNAJB5,RAB26,HOMER3,ARHGEF10,PDE4DIP,TOX,MFAP3L,SMG7,SPOCK3,ST8SIA3,SUGP2,EGFR,MRNIP,EN2,PLEKHO1,MTSS1L,FYB1,ZNF44,GPM6B,TDRKH,GPER1,GRK4,MEF2C,SCAMP5,PLCD1,PLXNB1,PTCH1,PTN,PTPRN2,PTX3,MSANTD2,RGS10,FBXW7,FOXRED2,SUPT20H,AMBRA1,CDK5RAP2,ELOVL4,PHLDB1,ASTN2,PCDHA5,ZNF34,TNS1,NAV3,AAAS" Drug 948_UP Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "C1QTNF3,CDC42BPA,APBB2,GAS7,PPFIA3,CDK13,MARCH3,GYG2,SCARB1,SRSF11,FOXN3,QKI,ENTPD4,CRY2,NCOR2,DZIP3,PHF14,GREB1,ARHGEF4,DCAF4,EDRF1,DTNA,DMTN,FER,MSL3,GPD2,GRB10,SLC2A6,SCRG1,IRF8,MBD1,NF1,NPTX1,PCDH9,PEX5,RGS10,RNASEL,NEK11,AMBRA1,ANKRD6,RAB3GAP1,SHANK2,EMC1,PHLDB1,ASTN2,SEMA4A,EXOC7,CRTC1,HIRA,MICAL1,MAP3K12,MPPE1" Drug 2294_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ABHD6,ANK3,ARRB2,MARK4,ATM,CFLAR,CDK5R1,CA4,PLEKHB1,VAX2,QKI,AKAP7,ARMC8,CHD1L,C2CD2,GPRASP1,DAPK3,DTNA,CINP,FAM49B,PRELID3A,HTATSF1,EML4,CNTRL,HNMT,ITPKB,JAK2,MBNL1,MIA2,LYRM9,NF1,NFYA,PDE3B,RETREG1,PRKAB2,TMEM104,ELOVL2,FBXO11,ANKRD6,PPP4R3A,BTBD7,SPTAN1,TSPYL2,TROVE2,SS18,TACC1,TCF7L2,TRIM2,SLC44A1,TMPO,DNAJC12,HPS4" Drug CID000000586 creatine Stitch 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "METAP1D,BRAP,FZD9,AK2,MYH7B,CACNA2D1,SLC22A6,SLC32A1,CS,AK5,DLG3,DMD,PIPOX,GTF2IRD2,AK8,GAA,DNER,GATM,GCK,GFAP,CIT,IGF1,MAPT,MBP,MTR,MYH3,MYH6,MYH7,PIK3C2A,PKM,PLP1,GSTCD,RYR1,RYR3,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A8,SLC6A11,IFT122,PALLD,HECW1,TRH,SGK3,CLIP2,SLC30A4,SLC17A7,ITM2C,SLC17A6,GJC2" Drug 2894_DN Thiamine hydrochloride [67-03-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "NME5,C1QTNF3,SEMA6A,EPB41L5,ARHGDIG,NUMB,RASL11B,CFLAR,ARHGEF2,GREB1,MED24,KBTBD11,EXOG,EFNA3,SORBS3,ING4,LRRC23,FGFR1,SEMA4D,USP19,GRB10,TJAP1,ITPKB,IPO5,TM6SF1,MITF,ADAM22,ZNF862,PCDH9,LRP12,MAPK10,TMEM104,RAB3A,TCP11L1,CLIP1,BCAN,SLC6A8,LIMCH1,CLSTN2,THSD1,MAPK8IP3,KIAA0930,TCF7L2,TMOD1,CDK20,VGF,VLDLR,ZNF24,PRDM2,SEMA3B,NAV2,EPM2A" Drug 6704_DN Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "RALGAPA1,APP,CFLAR,MTMR2,CANX,MAP7,KRIT1,CHM,TPP1,QKI,HOMER3,PDE4DIP,DZIP3,TBC1D5,DCTN1,FEM1B,FCF1,MBNL2,ETV1,FGFR1,ANKFY1,TRMO,OGA,FYN,TRAF3IP2,GLRB,NUDT21,EML4,IL6ST,LIG4,CNOT4,NUMA1,PLCD1,PPP5C,MAPK7,RAD51D,FAT4,KIRREL1,CLIP1,ZNF667,SPTAN1,TAB2,EPB41L3,SS18,KIAA0930,DICER1,BEX4,PARD3,CABIN1,UBTF,NSD2,PHTF2" Drug 5624_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "DPF1,SPARCL1,N4BP2L1,CCKBR,SEPT7,CACNA2D2,LHX2,CLCN4,NCOR2,CSF1,VCAN,SNPH,GIT2,EDIL3,ING4,REEP2,TUBB4A,DLC1,ZNF589,NSG1,GPR162,C1QL1,RND1,POLL,GRM1,ATXN2L,HTR2A,KCNK2,MDFI,FXYD7,NOVA1,PCDH9,CDK18,PDE4D,PLCB2,MTRF1L,POU3F4,MAPK10,ZSCAN2,SYNDIG1,KCNIP1,ZNF821,SLC11A1,TSNAXIP1,RBM26,SYT5,WSCD1,CRTC1,PIK3R5,OSBP2,WIPF1,DNALI1" Drug 7033_DN Thiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "NDRG2,SHROOM2,CDK10,ADAM15,CFLAR,STOML1,HOMER3,NCOR1,CSNK1E,CTNND1,TBC1D5,SMG7,SGSM2,ANKMY1,F8,FOXG1,FYN,SYT17,MSL3,RNFT2,PADI2,DHX35,KHK,KIF5C,NUMA1,RETREG1,STRN3,PTPRG,NKAIN1,RAB3IL1,ROBO1,PAQR6,MAPK12,SYBU,EPN2,SIRT2,ZHX3,ZBTB43,NCDN,CEP68,ATP11A,EXOC7,DNMBP,TRIM2,PCDHA6,ATP13A2,RPRM,VGF,REEP1,GDPD5,MPPE1,RNF170" Drug 4276_UP Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ASPHD1,PKP4,APC,ASCL1,BRINP2,N4BP2L1,CFAP410,CAMK2B,LDB2,CHI3L2,TAOK2,SULT4A1,RGS6,CTNND2,SEC14L5,RIMS3,DGKG,NTM,DTNA,EDNRA,HIPK3,DLC1,FYB1,SIGLEC8,GFRA1,GLS,GPR17,GPR22,IRAK3,KCNJ5,MAP2,MATN3,MOBP,MYT1,NNAT,NPTX2,PFKFB2,POU6F1,PRKCB,RAD52,ZCWPW1,SYNDIG1,SALL1,BCAN,SLC6A9,EFHD1,RIMS1,BEX1,ADGRL3,TCF4,OSBP2,EPM2A" Drug 4138_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "MRTFA,AMPH,RGS20,MARK4,BRINP2,ATM,CFLAR,RUNX1T1,SLC16A4,ZFYVE9,FADS2,ABI3BP,NRG2,CSF1R,ARHGEF10,SIPA1L1,EDRF1,NOS1AP,RIMS3,RUSC2,HS3ST2,ING4,ERCC2,FGFR1,CAMSAP1,AFF2,FAM49B,PRELID3A,GAB1,PRUNE2,GRB10,KCND3,VWA5A,TAGLN3,NDUFA5,NNAT,MAPK8,SAMD9,RGS12,EPN2,BTBD7,ZNF423,IQSEC2,THSD1,TBCEL,SMG6,PCDHGB6,R3HDM1,TRIO,XRCC4,GDPD5,KCNAB1" Drug 6981_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "AP2A2,TRMT9B,AMPD3,FAM131A,ST3GAL5,SYNJ2,ARHGEF6,AKAP7,CRMP1,CRY2,FEZ1,CSNK1E,CTH,DBN1,MFAP3L,DTNA,HIPK3,SIDT2,EIF4G2,ENO2,ZNF549,FECH,KIAA1109,FHL1,DISC1,RND1,TDRKH,KCNB1,KCND3,KIFC3,MAPT,ZNF862,NF1,NPTX1,PFKFB2,PHKG1,PROX1,FAM120C,RAB3IL1,C1orf54,NEK11,PAQR6,WLS,PEX26,SLC12A4,SLC22A4,UNC5B,ASTN2,SEMA4A,LMF1,ZNF24,SSPN" Drug 6938_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ASPHD1,KIDINS220,BIN1,AMT,CDC42BPA,APLP1,STX16,KIF1A,CFLAR,CHGB,TAOK2,TCEAL2,ARHGEF4,EDRF1,CTIF,DBT,OPTN,COQ7,EFEMP1,FOXG1,LPAR4,GPER1,GRK4,DIDO1,NR3C1,ELOVL5,JAK2,NAP1L2,NNAT,MAPK7,WDR25,KHDRBS2,RGS12,ROBO1,ROM1,HSPA4L,SH3BGR,DOP1A,SOX2,ZCCHC24,IQSEC2,COLGALT2,KIAA0930,PCDHGA10,AP4E1,SLC44A1,TRH,TRIO,TRPC3,FAM155A,KCNK12,XRCC4" Drug 4583_UP Terconazole [67915-31-5]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ASPHD1,ABHD6,C1QTNF3,PPFIA4,APC,SYNJ1,MYRF,CAMK2B,MAP7,KRIT1,ARHGEF2,CLCN4,CNTFR,AKAP7,CREM,CRY2,CTH,ING4,ETV1,REEP2,TRAF3IP2,GAP43,TMEM8B,LYVE1,RUNDC3A,GLYR1,GLRB,GPM6B,GPR17,GPR19,CNTRL,GRM2,PADI2,HNMT,JAK2,NPR2,PDE4D,PFKFB4,PTCH1,ENOX1,KIRREL1,SH3BP2,ST6GAL1,PKNOX2,EMC1,RAP1GAP2,NXT2,TRPC1,ZNF74,REEP1,SEMA3B,NAV3" Drug 4146_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.46E-05 1.00E+00 5.58E-04 6.35E-03 52 193 "ASIC1,KIDINS220,BIN1,AMT,CDC42BPA,ARRB1,ASPH,RASL11B,BTRC,CA4,B4GALT6,CRY2,SIPA1L1,NOS1AP,TBC1D5,GIT2,MAGI2,TMCC2,DTNA,FCF1,EZH1,ZNF589,FGFR1,KHDRBS3,TRAF3IP2,GAD2,SEPT9,GNG4,ATXN2L,IGSF1,JAK2,KCNH2,KCNN1,SMAD1,MATK,NEK1,NF1,RETREG1,MBOAT7,RIPOR1,RPS6KA2,KCNIP1,EMC1,CLSTN2,PHLDB1,KAZN,TBCEL,HEY2,UCHL1,ZNF24,GDPD5,KAT6A" Drug CID000004284 DETA Stitch 4.46E-05 1.00E+00 5.58E-04 6.35E-03 35 114 "KCNH8,ACHE,SEMA6A,SEMA7A,SEMA4G,BCHE,NRP2,SLIT2,DCC,DMPK,PTK2B,SEMA6C,EVL,SEMA4D,GAD1,GAD2,KAT7,MAG,NELL1,NELL2,NPTX1,OMG,ABCB1,PLP1,MAPK9,PTK2,ROBO1,ROBO2,SEMA6D,SLIT1,SEMA4A,ROBO3,CNTN2,SEMA3B,RTN4" Drug 6089_DN Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,APBA2,GAS7,ARHGDIG,DNAH17,MARK4,CADM3,BTRC,HAP1,CAMK2G,LHX2,ZFYVE9,FAM189A2,TBC1D5,RIMS3,MFAP3L,DTNA,HIPK3,EFNA3,ING4,C3orf18,F3,BAIAP2,FOXG1,GFER,POLL,RNFT2,MAP4,MSI1,SLC11A2,RETREG1,MAPK7,TMEM104,ZSCAN2,RAB3A,RAD51D,SH3BP2,BCAN,KIF13A,KDM4B,SOX2,ST5,NCDN,MAPK8IP3,VPS13A,SEMA4A,MCF2L,EXOC7,TK2,TPM1,TRPC1,VIPR2,SSPN" Drug 6332_UP Proparacaine hydrochloride [5875-06-9]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "KIDINS220,CDC42BPA,GAS7,SEMA4G,PTCH2,KIF1A,CACNA1I,MAP7,RUNX1T1,LHX2,ABCG2,CABP1,NCOR2,AATK,CSNK1E,PDE4DIP,CTNND2,RIPOR2,ARHGAP24,DTNA,FAM13A,RASGRP2,AFF2,DISC1,KLF12,VWA5A,MAPT,MDFI,ADAM22,MYL3,NDP,NUMA1,PBX1,PMP2,GAL3ST4,KCNIP1,FOXRED2,FRMPD1,DOCK10,SLA,SLC2A5,SLC20A2,WDTC1,HECW1,CEP68,ASTN2,ATP11A,SYNE1,NSD1,CRTC1,FLRT2,NUP214,DPF3" Drug 2394_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "BRAP,PLA2G6,ALK,APP,ASPH,NCOA1,BCL7A,LDLRAD4,CAPN3,CD86,TMEM184B,IQCK,C2CD2,OSBPL3,VCAN,CX3CR1,TRAPPC9,DTNA,ABI2,SORBS3,COQ7,VPS26C,FECH,TPK1,LILRA2,GPR22,LPAR4,EML4,IFI16,ITGA7,MAP4,SLC11A2,RETREG1,LRP12,PTAFR,RAB5B,RET,ATXN2,CCDC88A,ZBTB43,DDN,MAPK8IP3,FAM168A,ATP11A,EXOC7,TCF7L2,HIF3A,SLC44A1,TK2,KAT6B,ATP6V0E2,PRDM2,ST7" Drug CID000449606 AC1L9NAZ Stitch 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRB2,APLP1,DST,CCKBR,CHRM1,CNR1,HDAC9,DLG3,CALCRL,EPB41,ERBB4,TUBB3,GFAP,GPER1,STMN2,GRM1,GRM2,GRM5,GRM8,CIT,HRH3,MAPT,NELL1,NELL2,NPY,SLC11A2,OPRL1,P2RY1,ABCB1,ASAP3,SLC11A1,SSTR1,SSTR2,TAC1,TACR1,CNTN2,ANO4,TCF4,TCF7,TCF7L2,AKTIP,ICAM5,TPM2,TPM3,TRH,TRPC1,ANO5,VIPR2,P2RY12" Drug 3258_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,FZD9,LTBP4,PPFIA3,PDXK,RASL11B,CLGN,ADGRG1,CHRNB2,HOMER3,AKAP7,WHRN,RIMS2,SIDT2,ING4,EPB41L1,DMTN,ZNF589,FHL1,GAB1,KHK,MDM4,KITLG,GIT1,NUCB1,PALM,CDK14,PGAM2,PLTP,PRKAR1B,PTN,PEX5,CCDC40,C1orf54,RGS3,RXRA,FOXRED2,ZNF821,SH3BP2,ARHGEF40,KDM4B,NPAS3,THSD1,ARC,SZT2,DOCK9,OBSL1,ZNF34,TNS1,TRIO,PLPPR2,WIPF1,SPHK2" Drug 4370_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,AP2A2,SEMA6A,MRTFA,AMPD3,APBA2,APBB2,APC,APP,PPP4R4,SLC2A11,GYG2,CACNA1I,ADGRG1,CHRNB2,WHRN,NECTIN3,CSF1,FAM169A,RIMS3,IGSF6,DPYSL4,TRAF3IP2,GAD1,MSL3,GNAS,GNG3,GNG4,GRIK5,ICA1,IL6ST,KIT,KITLG,MMP16,NF1,NTRK2,RETREG1,MBOAT7,PTN,FAM120C,ZDHHC14,ZFHX4,TCP11L1,EMC1,PLCB1,ZEB1,CRTC1,VGF,PRDM2,KCNAB1,ITM2C,SMIM8,NUP214" Drug 3748_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "AP2A2,APAF1,PDE8B,BRINP2,ATP6V0A1,NRP2,SCAPER,CLDN10,DCLK1,SULT4A1,ATRNL1,HS3ST2,DRP2,DTNB,HEYL,FGF1,FLT1,ALDH1L1,PCDH17,RND1,GPM6B,ATF7,GRM2,GRM3,PADI2,ICA1,IL6R,ITGA7,KCNJ5,KCNN1,MARK1,MMP16,MYO7A,NPTX1,PCDH9,PDE1B,FXYD1,PLP1,SPATA6,PACSIN1,PTCH1,PTN,PTPRH,RASGRF1,RGS12,RTN1,SLITRK3,PREX2,ZC3H13,MCF2L,THBS4,NPL,MAP3K12" Drug 7373_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,AMPH,CDC42BPA,CDC14B,CFLAR,CACNA1A,CAMK2A,AKAP5,CNTNAP2,CTNND2,ARHGAP24,TBC1D5,CTIF,DTNA,DUSP9,FCF1,EFEMP1,FGFR1,AGAP2,DPYSL4,LPAR4,PTGDR2,IL12A,KCNK2,KITLG,MYO7A,NF1,CNOT4,CLDN11,PTPRH,PTPRN2,RIPOR1,RAB3A,RGS7,ARHGEF10L,MYH14,SCG5,PPP4R3A,KANSL3,TNIK,IZUMO4,IQSEC2,ZBTB43,VAMP1,SYN2,SYT1,ARHGEF12,GPR161,THRA,ZKSCAN5,LMF1,SEMA3B,KCNAB1" Drug 2118_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABHD6,BEGAIN,LGR5,PPP4R4,CA12,RAB28,QKI,NRG2,VCAN,SLITRK5,CNIH3,KBTBD11,DLG3,EGFR,PLEKHA1,STX2,PIPOX,ST3GAL6,SEMA4D,TRMO,PDLIM5,AHCYL1,GLYR1,GPM6B,HNMT,KIF5C,MATN3,GIT1,NF1,GPR85,STRN3,NECAB2,SIDT1,PTPRB,SUSD4,RGS4,RGS7,RGS12,SEMA6D,PKNOX2,ERC1,UNC5B,ZBTB43,LHPP,KAZN,IQCE,CHST8,TIAM1,BCL2L13,VIPR2,SPHK2,MAP3K12,SEMA3B" Drug 5533_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABHD6,AP2A2,AK2,DGKD,APP,PPP4R4,NCOA1,SLC4A4,RIPK1,ST3GAL5,SYNJ2,SCAPER,SLC25A14,ABI3BP,CREM,ABCG1,CSNK1E,KIAA0586,EFNA3,VPS26C,TRMO,TDRKH,BTN2A1,KCNF1,KCNQ3,KHK,KIF5C,MAP4,MPP2,MSI1,ADAM22,SETD4,SMOX,MAPK8,RGS3,SBF1,BCAN,PREX2,SCMH1,SMARCA4,IFT122,ZBTB43,POGZ,ARHGEF9,ASTN2,TRIM2,TGFBR3,PIK3R5,NPL,ZNF384,MPPE1,KAT6A,RNF170" Drug 2175_UP Dipyrone [5907-38-0]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADD2,BIN1,LGR5,BTRC,CDC42,LARGE1,LHX2,CREM,CNTNAP2,DLG3,SHANK1,EGFR,ELN,FGF12,OGA,TMEM8B,INPP5K,GATM,ALDH1L1,GRM1,ATXN2L,SCRG1,TJAP1,KCNJ4,MGAT3,MSI1,ADAM22,MYCN,MYO6,NPPA,PCDH9,PFKFB4,PTPRN2,RASGRF1,SEC61A2,ZFHX4,KLHDC8A,CPEB3,SLC12A4,SLN,RBM34,UNC5B,HIF3A,GPR161,KCTD2,CHST5,TRIO,TRPC1,UGT8,LMF1,ZIC3,ZBTB38,GAN" Drug 3211_UP "Zidovudine, AZT [30516-87-1]; Up 200; 15uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ARID1A,ADD2,ADGRF5,APAF1,CDK13,SLC4A4,BTRC,CACNA1D,CBFA2T2,TPP1,BAG4,OSBPL3,VCAN,RIPOR2,MFAP3L,FRY,ERCC2,EFS,REEP2,FGFR1,SCARA3,PRELID3A,DLL3,SIGLEC8,SRCAP,GRIK5,CELF3,IRF8,KCNMA1,KCNN1,KCNN2,KIT,MOBP,ADAM22,BCO1,NOVA2,PCBP3,OMG,PDE3B,PPP5C,CNNM2,PTHLH,TCP11L1,SGK1,SLC11A1,ATP11A,MTCL1,TGFBR3,THBS4,TNS1,FLRT2,CLIP2,ZNF711" Drug 4759_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG3,LTBP4,AMPD3,BIN1,APOC1,MARK4,SLC2A11,ARHGEF2,CLGN,TAOK2,PDE4DIP,NOS1AP,HSD17B14,DMTN,DLC1,ZNF589,KIAA1109,FHL1,GAB1,INPP5K,GLS,POLL,GNG4,CNTRL,GRM8,ATXN2L,INPP5B,KCNF1,LMO2,MEF2C,MIA2,MYT1,P2RY1,RGS3,ZFHX4,SYBU,SLC1A7,BTBD7,DOP1A,SOX2,EMC1,ZC3H13,IQSEC2,MAPK8IP3,PLCB1,KIAA0930,PCDHA5,HEY1,PARD3,CDK20,MICAL1,SCG2,ADAMTSL3" Drug 3237_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "APC,PTCH2,ADGRB2,CA4,CACNA1D,CBFA2T2,RAB33A,TPP1,FAM189A2,SULT4A1,BAG4,VCAN,RIMS2,CYBB,SNPH,KIAA0513,RASSF2,CTIF,DYRK1A,EDNRA,EDNRB,EFNB3,AFF2,PRELID3A,GNG3,ITGA7,KCNJ5,KCNN1,KIT,IPO5,MDFI,MEIS1,CLDN11,PALM,PLCD1,MAPK7,GRAMD1C,RIPOR1,KCTD17,SH3BP2,SYBU,SLC2A5,DHX30,SHANK2,SLC22A4,SOX10,CAND2,ARHGAP26,ACSBG1,EXOC7,RIMBP2,R3HDM1,XRCC4" Drug 4104_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ALCAM,AMPD3,GAS7,ATP2B2,BAIAP3,CACNB4,IFFO1,NRG2,AATK,CSF1,RUSC2,CDON,EFNB3,RASGRP2,FGFR3,DCTN2,CSPG5,DLL3,GABRA2,GAD1,SIGLEC8,RND1,GNAO1,GRM1,GSTM5,ATXN2L,VSIG4,HTR2A,SHISAL1,MATN3,ZNF862,NOVA2,NTRK3,PCDH8,PDE1C,MAPK7,PTHLH,ELOVL2,ZNF493,SBF1,SH3BP2,FRMPD1,SLC2A5,LIMCH1,SP4,SYT11,SYP,EXOC7,WWC1,WSCD1,SYNE1,TLR4,VSNL1" Drug 3736_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADRA1D,NME5,ALK,APAF1,APBB1,GAS7,PPP4R4,ALDH7A1,NRP2,SYNJ1,ARHGEF2,CHM,TAOK2,CLCN4,NCOR2,CNTNAP2,EDRF1,MFAP3L,EXOG,ECM2,EDNRA,SEMA3D,MBNL2,LPAR6,EPHA5,EPHB1,KIAA1109,GLS,GPD1,GPR19,GRM2,MAP4K5,KCNH2,LIG4,ADAM22,CNOT4,CLDN11,PDE2A,PIK3CD,POU3F4,PROX1,SYTL2,KHDRBS2,RPS20,ZNF334,EFHD1,RBM34,TNIK,ATP10B,INKA2,CADM1,FLRT2,KCNAB1" Drug 1299_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ACLY,NDRG2,AMPD2,ANK2,PPFIA4,NCOA1,ATP6V0A1,BCL7A,SCAPER,ARHGEF1,SEC31B,INTS1,DBN1,SMG7,DTNA,PHF20L1,SUGP2,TNK2,MRNIP,EZH1,NOP56,LILRA2,SLC2A6,VSIG4,AGBL5,IRF8,ITGAM,VWA5A,MAP4,MATK,NUCB1,PLCB2,PTPA,RNASEL,MCMBP,RPS6KA2,SH3BP2,COA1,SMARCC2,SPTAN1,NCDN,MAPK8IP3,DIP2A,GSE1,VAMP1,CAMSAP2,PDLIM2,NSD1,R3HDM1,TNNT1,WBP2,LAMP5,WIPF2" Drug 6326_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASPHD1,MTUS1,ADGRF5,APAF1,APC,EPB41L5,ALDH4A1,KIF1A,CFLAR,SYNJ2,MTMR3,SCARB1,B4GALT6,CHRNB2,NRXN3,AKAP7,WHRN,CTNND2,ARHGAP24,MAGI2,PARD6A,EFNA3,FAM13A,PLEKHO1,F5,FGF1,C1orf61,PNMA2,GABRA2,SIGLEC8,SEPT9,GFER,HTR2A,KCND3,GIT1,NDP,NOVA2,NUMA1,PTPRH,RAD52,ZCWPW1,RASGRF1,NEK11,KCNIP1,KIF16B,SLC6A9,EMC1,KDM4C,CRTC1,CABIN1,VGF,SCG2,KCNAB1" Drug 3871_UP Nialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,ALCAM,ASPH,CHRD,NRP2,CACNA1I,CACNA1G,CAMK2B,QKI,CNTN1,PLCH2,CNTNAP2,SEC14L5,CYBB,SV2B,RABGAP1L,RASGRP2,FGFR3,CAMSAP1,CAMKK2,KHDRBS3,TBR1,FYN,GLYR1,MSL3,GPM6B,GRIK5,GUCY1A2,TJAP1,KCNJ5,KIT,MAPT,MID1,AFDN,MYT1,NNAT,NPTX2,NTRK3,C19orf57,ZSCAN32,TCP11L1,RPS6KA2,SATB1,ZFP2,SLC2A5,IZUMO4,SYP,ROBO3,DOCK9,TMOD1,TRPM2,SLC30A3,MVB12B" Drug 6957_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASPHD1,DOC2A,AMPD3,MAP4K3,APLP1,CDC14B,ATM,SYNJ2,CALB2,ARHGEF2,MAGI1,PLEKHB1,EPS15L1,PLAA,HOMER3,CREM,PDE4DIP,SDC3,EGR3,PLEKHA1,LRRC23,EFEMP1,FOXG1,EFCAB2,DPYSL4,GPR153,SIGLEC8,INPP5K,MEIS1,MITF,MSI1,NEUROD1,NFYA,RETREG1,FAM120C,RAD52,TCP11L1,SFPQ,SLC20A2,CXXC4,KDM4B,SOX3,SPART,MAPK8IP3,ARHGEF9,ASTN2,EXOC7,CRTC1,SIK3,TMPO,MICAL1,REEP1,STMN4" Drug 2155_UP Vitexin [3681-93-4]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,MTUS1,ALK,BIN1,CDC42BPA,LGR5,CASK,CFAP410,THSD7A,CHN2,NMT2,STOML1,CREM,PPP1R16B,USP6NL,HEPH,RUSC2,SGSM2,EDIL3,ERBB2,CAMSAP1,HPCAL4,ALDH1L1,GPR19,GRM2,TJAP1,KCNJ3,MAP4,MYO9A,ZNF862,NCAM1,NNAT,PDE4A,PFKFB4,PTPA,PTPRN2,RIPOR1,MARCH1,RAB3A,FAT4,RFX2,MAP6D1,ITSN1,ST6GAL1,ZCCHC24,SOX10,FAM168A,EXOC7,CRTC1,TEX15,CLIP2,SPHK2,EVI5" Drug 6702_UP Niacin [59-67-6]; Up 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "OGT,ANK1,APAF1,APC,DDO,ARHGDIG,CDK13,NRP2,LDLRAD4,CFAP410,KALRN,RUNX1T1,CBFA2T2,ARHGAP33,CHI3L2,CHRNA4,PCYT1B,NCOR2,CSF1,MICAL2,SDC3,MFAP3L,ABCC9,EFNB3,ING4,RASGRP2,CEND1,ST3GAL6,FYN,GPM6A,ITGA7,AFDN,ADAM22,NEUROD1,SLCO1C1,P2RX7,P2RY1,SNTG1,PALM,PIK3R1,PMP2,PTPRN2,RALGDS,SUGCT,FRMPD1,SLC6A9,SLC9A5,IZUMO4,PCDHGB6,TF,HIRA,EVI5,FAM13C" Drug 2492_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "SPARCL1,BEGAIN,ANK2,ANK3,APC,PPFIA3,ATP6V0A1,BCL2L2,NRP2,BTRC,CALB2,CAPN3,SLC16A4,CDH2,CRLF1,ZFYVE9,CLCN4,AKAP6,RCHY1,CREM,CRMP1,DCT,EDNRA,HIPK3,EFNA3,RASGRP2,STX2,KHDRBS3,NEU3,HPGDS,GRIK5,GRIN1,IL1RAPL1,MAP4,CD200,TAGLN3,NPTX1,PBX1,PFKFB2,CEP41,STUM,SLN,PALLD,ZHX3,SPTAN1,PHLDB1,DNMBP,ATP13A2,CDK20,FAM155A,SPHK2,KCNAB1,JPH3" Drug 5334_UP Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "MRTFA,APC,BCAS1,MARK4,ATM,ST3GAL5,MTMR2,GPR37L1,HOMER3,CTH,GREB1,HDAC4,KIAA0586,TMCC2,E2F5,SH3GLB1,LRRC23,ZNF589,FGF12,ANKFY1,SRCAP,TXNL4A,GLYR1,GRB10,ELOVL5,HSF2,IL6ST,ZNF862,NEK1,NPR2,PRKAR1B,LRRC49,PTHLH,RAD51D,RALGDS,FAM184A,SBF1,SYBU,ANKRD6,EPN2,BTBD7,SMARCC2,TTC17,THSD1,VPS13A,ARC,SATB2,TRIM2,AP4E1,ZNF34,TIAM1,XRCC4,ST7" Drug 7267_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,ARID1A,MTUS1,MARK4,SYNJ2,CACNG1,RUNX1T1,NRXN3,ZFYVE9,CREB5,VCAN,SLITRK5,ARHGEF4,EDRF1,FAM131B,SMG7,DTNA,FEM1B,FAM13A,EGFR,RGS17,BAIAP2,TRMO,ZNF274,SRCAP,FERMT2,MUM1,IFI16,TJAP1,IL6R,INPP5B,PDE4D,PMS2,MAPK3,ROGDI,ROBO1,CSRNP3,SLC9A5,SMARCD3,MYH15,TMCC1,TNIK,ZHX3,RAP1GAP2,THSD1,ELOVL4,DIP2A,SMG6,MICAL1,NDRG4,HPS4,NAV2,RNF146" Drug 7556_DN vinblastine sulfate; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,ABHD6,NDRG3,PPFIA1,APC,APOC1,ARNTL,MARK4,CFLAR,SYNJ1,ARHGEF7,BAIAP3,CBS,CNOT8,CHD1L,TENM4,CNTNAP2,SDC3,LYPD1,RHOBTB1,EDIL3,EDNRA,FCF1,EFNA3,SORBS3,IRAK4,TUBB4A,CINP,GLYR1,MSL3,HAS2,KLF12,SCIN,JAK2,MMP16,MPP2,NACA,NF1,PFKFB2,VPS13C,PTN,SBF1,IL17RB,ITSN1,SLC14A1,CDK5RAP2,TNIK,POGZ,ELOVL4,ARHGEF9,VPS13A,FBXW11,LMF1" Drug 2154_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABR,BMP7,CDK5R1,LDLRAD4,CHM,HOMER3,SLC4A7,CSNK1E,ZNF337,TBC1D5,KIAA0586,SMG7,RABGAP1L,DPH1,HIPK3,FCF1,ING4,TUBD1,LRRC23,AGAP2,FLT1,GATM,ADAM28,GLYR1,CACFD1,KCNJ5,MX1,OGG1,NLE1,PLEC,SLC25A23,PLTP,PMP22,RAB3A,GALNT10,SH3BP2,ITSN1,SLC11A1,SP4,IZUMO4,EMC1,CAND2,KDM4C,RAP1GAP2,SS18,PLCB1,DNMBP,TCF4,TMOD1,PARD3,REEP1,URM1,ST7" Drug 2400_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABHD6,ADD2,SEMA4G,CACNA1I,MAGI1,CDO1,SLIT2,SLC24A2,CREM,ENTPD4,CHD5,DCAF4,SNPH,DNAJC6,DLG3,EFNA3,LRRC23,CEND1,OLFM1,GAB1,INPP5K,GLYR1,GLS,ATXN2L,ICA1,KCNJ5,KCNN1,SCAMP5,NELL2,PDE3B,CAMKV,PACSIN1,MAPK8,FBXW7,KCNIP1,SLC30A10,SH3BP2,ZNF365,SLC1A7,PEX26,UNC5B,PEG10,SS18,MAPK8IP3,PHLDB1,DNMBP,PDLIM2,CUX2,NSD1,CRTC1,TGFBR3,TPM1,UGT8" Drug 6270_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "BIN1,SEMA7A,SYNJ2,CACNA1A,KYAT1,CCNT1,B4GALT6,TAOK2,ZFYVE9,VAX2,AKAP7,NRG2,SDC3,DCAF4,DOCK4,RCAN1,COQ7,DLC1,KAT8,BAIAP2,FAM49B,GABRA2,SRCAP,HNMT,KCNF1,CD200,NDUFA5,NPR2,NUMA1,PALM,RETREG1,NLE1,PPARA,CEP97,RGS10,RNASEL,DCUN1D2,GSTCD,FBXW7,KCNIP1,ZNF331,FNDC3A,SMTN,FAM214B,EFHD1,RBM34,CDK19,MAPK8IP3,EXOC7,DNAH7,TMEM121,METTL3,HPS4" Drug 7481_UP (-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "AMPH,BIN1,ANK1,KCNAB2,APC,SEMA4G,SLC4A4,KIF1A,BMP7,SYNJ2,CBFA2T2,SOCS6,RAB33A,PLAA,NCOR2,JAKMIP2,MAGI2,CELSR3,MRNIP,KCNMB2,FABP7,FECH,GPR153,USP19,RAB30,GPR37,AP4S1,TJAP1,INPP5B,ITPKB,KCNN1,MATK,NUMA1,PLXNB1,MBOAT7,MAPK8,RIPOR1,RGS4,ZFHX4,SLC20A2,WDTC1,ELOVL4,STX1A,ACSBG1,KAZN,CRTC1,ZNF34,TIAM1,TK2,PARD3,VIPR2,KCNK12,SEMA3B" Drug 1712_UP Dirithromycin [62013-04-1]; Up 200; 4.8uM; HL60; HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "CNTNAP1,CDK10,SEMA4G,PDE8B,SLC4A4,ADGRB2,CA12,CACNA1A,CALB2,CDH10,CACNA2D2,FOXN3,CHN2,CNTFR,SH2B1,TMCC2,TRAPPC9,TNK2,SRPK3,ELN,CEND1,ALDH1L1,GJB1,GRIK1,CACFD1,GSTM5,KCNF1,KIF5A,MBP,GIT1,SAMD14,MYT1,OMG,DUSP26,PACSIN1,PPARA,PPP5C,PTK2,PTN,PTPRN,RXRA,SEMA6D,BCAN,SLC1A7,LIMS2,ZC3H13,PHLDB1,SYN2,DNAH7,LILRA4,ZMYND8,VGF,VSNL1" Drug 5243_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,ADRA1D,PLA2G4C,ALDH4A1,STX16,CFAP410,HAP1,QKI,ARHGEF4,USP6NL,NOS1AP,DCAF8,RASSF2,TBC1D5,MFAP3L,SLC12A6,DSCAM,SIDT2,EGFR,PLEKHO1,CAMSAP1,PRELID3A,SRCAP,GLS,GNG4,PCLO,KCNH2,NF1,PRKAR1B,PRODH,RGS10,TCP11L1,RPS6KA2,DOCK10,FBXO11,SLC9A5,SHANK2,BTBD7,SNCA,ZCCHC24,KDM4C,THSD1,ST5,MAPK8IP3,ARHGEF12,PCDHA6,PCDHA5,TPD52,CDK20,VAV2,KCNK12,EPM2A,ST7" Drug 2554_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ANK3,PKP4,APBB2,PPP4R4,BMP7,CACNA1G,CFAP410,AP4M1,ARHGAP33,CLGN,ZFYVE9,HOMER3,NRG2,SLITRK5,CTNND1,RIMS2,SV2B,E2F5,HIPK3,EFNA3,FAM13A,OLIG2,ZNF549,CDKL3,FOXG1,PDLIM5,CAMKK2,DKK3,GPD2,GSN,KLF12,MAPT,ZNF862,PURG,STRN3,SEC61A2,SYNDIG1,CPEB3,PREX2,ARHGAP26,RAP1GAP2,SPART,ATP10B,ARHGEF9,SYT1,POPDC3,AHCYL2,HIF3A,TMOD1,PIK3R5,RBFOX2,TRIO,JPH3" Drug 6257_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,NDRG2,ADCY6,PLA2G6,SYNJ2,BAIAP3,CLDN10,SOCS6,FAM189A2,HAPLN1,CRY2,GREB1,CTNND2,CTIF,GIT2,TOM1,EFNA3,EGFR,TNK2,EPB41L1,COQ7,FGFR1,GABRA2,HBS1L,INPP5K,USP19,GRIK5,DHX35,IL6ST,KCNH2,VWA5A,TM6SF1,ZNF862,NUMA1,RETREG1,PILRA,CNNM2,WDR25,ATXN1,SYBU,SMTN,SHANK2,BTBD7,SNCA,ZNF423,SPTAN1,ASTN2,OBSL1,ZNF34,CABIN1,FLRT2,HPS4,SSPN" Drug 6055_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "AMPD3,BIN1,AMT,APLP1,APOC1,MARK4,RHBDL1,ASIC3,SULT4A1,ARHGEF6,WHRN,CNTNAP2,INTS1,DGKG,BRINP1,GSDME,ATN1,ELAVL3,NCALD,CORO2B,FUT9,GCNT2,ADAM28,PCDH17,GRIN2C,KLF12,KCNJ5,MDFI,ADAM22,BCO1,SLC11A2,OPCML,CDK14,MTRF1L,MAPK7,TRIM68,CARF,SMPD3,SLC1A7,IZUMO4,SPART,TROVE2,INKA2,JMJD6,DNAH7,TIMP4,TPM1,TRH,UCHL1,LAT2,ITM2C,MVB12B,NUP214" Drug 4750_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,AMPD3,GAS7,PLA2G4C,MARK4,ASPH,SLC2A11,ALDH7A1,SLC25A14,CLGN,PLEKHB1,HOMER3,SLC4A7,CREM,CTH,GREB1,SLC12A6,DRD1,EDNRA,EFNA3,EFNB3,NCALD,DLC1,ST3GAL6,C1orf61,AFF2,SRCAP,GNG4,PCLO,NR3C1,ATXN2L,JAK2,MEF2C,MPP2,NEK1,NNAT,STRN3,LRP12,MAPK7,FAM120C,RGS10,SBF1,ZNF821,SLC1A7,FAM214B,SLC15A2,RBM34,WDTC1,ZC3H13,CLSTN2,CEP68,ZNF711,SSPN" Drug 7505_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,NDRG3,BRAP,LTBP4,CDC42BPA,APC,GAS7,APLP1,KIF1A,MTMR2,C5,CA12,CAMK2B,TAOK2,DNAJB5,ABCG1,SOCS5,PDE4DIP,MED12,DTNA,PRELID3A,GAD1,GLS,GPER1,GRB10,ADAMTS13,RASSF8,ELOVL5,LMO2,MITF,SETD4,OCRL,PDE3B,PDE4A,SLC25A23,MBOAT7,FAM120C,TMEM231,SEMA6D,IL17RB,ZNF821,TROVE2,THSD1,ELOVL4,ARC,SMG6,SZT2,PCDHA6,TPD52,VIPR2,ZNF189,EVI5,SSPN" Drug 3367_UP Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADORA1,C1QTNF1,BEGAIN,APAF1,N4BP2L1,CACNA1I,CAMK2B,USP2,AKAP6,CPS1,DCT,TMCC2,USH1C,MBNL2,TNK2,EN2,RASGRP2,MTSS1L,PTK2B,TUBB4A,GAD1,SIGLEC8,GRM7,GRM8,ICA1,KCNB1,KCND3,KIF5A,MEF2C,MOBP,ADAM22,TAGLN3,ZNF862,NPR2,PDE4D,LRRN3,PPP5C,SAMD9,RAB3IL1,RNASE1,SH3BP2,NTNG1,KIF21B,ZC3H13,ATP10B,AJAP1,ATP11A,WSCD1,PCDHGA10,PARD3,FLRT2,WIPF1,GDPD5" Drug 6501_DN Aminocaproic acid [60-32-2]; Down 200; 30.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "AP2A2,AMT,APLP1,CDC14B,CAPRIN2,NCOA1,BTRC,MAGI1,CREM,ABCG1,CSNK1E,DZIP3,DAPK3,GIT2,DSCAM,EDNRA,ING4,ENO2,DENND4A,GPR153,MALT1,GNG4,GPR37,GRIK5,INPP5B,KCNH2,KCNJ3,MAPT,MIA2,NUCB1,OCRL,PDE3B,CNNM2,TCP11L1,SAFB,SBF1,ZNF821,EPN2,FAM214B,SLC20A2,RBM34,KDM4C,NXT2,TTBK2,NSFL1C,EXOC7,TCF7L2,PSD3,TNS2,AHCYL2,TPM1,XRCC4,SYNC" Drug 1543_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,ASIC1,ABHD6,ADORA1,BIN1,APBA2,APBB2,ATM,SYNJ2,CACNA1I,AKAP7,NCOR1,ATRNL1,JAKMIP2,EFNB3,TENM1,FGFR1,BAIAP2,FHL1,ADAM28,TXNL4A,STON1,GSN,ELOVL5,TJAP1,IL6ST,ITIH2,KCNJ5,KCNQ3,IPO5,ADAM22,NF1,NTRK2,CDK18,NLE1,PLCD1,PPP2R5C,PTHLH,PTN,RAB5B,MYH14,RPS6KA2,ASAP3,DOCK10,UNC5B,ITPRID2,SAMSN1,HIRA,KCNK12,ZIC3,SLC30A3,EPM2A,SENP7" Drug 2088_UP Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABAT,MRTFA,AMH,PPFIA4,DDO,CHGA,CREB5,RIMS3,KIAA0319,SMG7,PLPPR4,DTNA,HIPK3,DMTN,SEMA4D,C1QL1,GNG4,PTGDR2,ICA1,KCNQ3,CNOT4,NTRK3,PAK3,PDGFRA,GPR85,STRN3,PRKAR1B,BCAS3,PTPRN2,TMEM231,ACSS3,RAD52,GAL3ST4,RGS4,RGS10,FOXRED2,MRAS,ZFP30,ASAP3,BCAN,ARHGEF40,SNCA,ZHX3,INKA2,MAPK8IP3,JMJD6,VAMP1,SYN2,SEMA4A,CRTC1,TIAM1,SEMA3B,KCNAB1" Drug 5955_DN estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC2,AP2A2,ALK,AMH,AMPD3,FAM131A,CDC14B,PLA2G4C,DNAH17,ATP2B3,CA12,CLGN,TPP1,VAX2,AATK,SDC3,MFAP3L,ING4,DMTN,DLC1,FOXG1,PRUNE2,GPM6A,NR3C1,GRM2,ELOVL5,ICA1,KCNN1,VWA5A,MMP16,MX1,NNAT,CNOT4,PALM,PCDH9,SLC25A23,PPP2R2B,KCTD17,RPS6KA2,SLC1A7,SLC11A1,SLC14A1,DOP1A,EMC1,SPTB,SYN2,KIAA1107,ARHGEF12,DICER1,THRA,NT5M,DNALI1,KCNAB1" Drug 4627_UP Altretamine [654-05-6]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "APBB1,APBB2,APC,PPP4R4,CADM3,CA12,ADGRG1,SOCS6,RAB28,STOML1,HAPLN1,CSF1,VCAN,PDE4DIP,CNTNAP2,C2CD2L,HIPK3,FCF1,SIDT2,ETV1,C1orf61,DPYSL4,FYB1,GABRA2,GNG4,STON1,GPER1,GRIK5,KLF12,HSD17B1,PACRG,ADAM11,SCAMP5,MMP16,TAGLN3,CLDN11,PAK3,PIK3R1,RETREG1,MYH14,PPP1R9A,ANKRD6,SLC6A11,SLC20A2,RIMS1,ZHX3,ARHGAP26,PHLDB1,SEMA4A,TCF4,SLC44A1,MVB12B,NUP214" Drug 7130_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "GAS7,CDK10,ALDH4A1,KIF1A,BTRC,KYAT1,CSF1R,OSBPL3,PDE4DIP,CNTNAP2,CTNND2,CYBB,RIMS3,RUSC2,SGSM2,DSCAM,MAMLD1,EN2,LRRC23,EFEMP1,FCGRT,ZNF589,FER,OGA,GAD1,USP19,C1QL1,GLRB,RNFT2,INPP5B,NDUFA5,PDGFRA,PLCD1,MAPK7,KLK6,CNNM2,BCAS3,PTN,PTPRN2,SBF1,SH3BP2,ST6GAL1,WDR37,LIMS2,ZKSCAN3,TSPYL2,PHLDB1,PLCB1,WIPF1,NSD2,MPPE1,EPM2A,ST7" Drug 5512_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABR,ACTN2,NDRG2,AGT,CDK10,SPTBN4,PLA2G4C,CADM3,SCAPER,MTMR3,CLGN,QKI,AKAP7,SNCAIP,CSF1R,RGS6,SIPA1L1,EDRF1,SEC14L5,DCC,SIDT2,HSD17B14,CORO2B,FGFR1,TPK1,GPR162,RUNDC3A,GNG3,ACOT7,HNMT,IL11RA,INPP5B,KCND3,VWA5A,MOBP,ADAM22,NOVA2,NLGN3,SLC25A23,STRN3,PRKCB,DIRAS2,GTDC1,RPS6KA2,SLCO1A2,SLN,UNC5B,MCF2L,WSCD1,TK2,FLRT2,KCNAB1,NUP214" Drug 7304_DN Trolox [53188-07-1]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "C1QTNF1,MRTFA,APOC1,PPFIA3,CASK,EIF4G3,MPDZ,SCAPER,SRSF11,ZFYVE9,NIPBL,HINFP,DCAF4,ARMCX2,KIAA0753,LYPD1,DYNC1I1,EFNA3,FAM13A,ZNF589,SCARA3,ATP2C1,B4GALNT1,INPP5K,SESN1,CNTRL,SHISAL1,DIPK1A,MBD1,MX1,PPP5C,MAPK3,BCAS3,FAM120C,GTDC1,KIRREL1,FBXW7,FAM102A,FUZ,AMBRA1,ANKRD6,BTBD7,COA1,SMARCD3,LIMCH1,GSE1,DNMBP,ZNF34,R3HDM1,CABIN1,TPD52,LMF1,WNT7A" Drug 6073_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "BEGAIN,BIN1,CDC42BPA,SEMA7A,PLA2G4C,N4BP2L1,BAIAP3,ARHGAP33,SULT4A1,HAPLN1,CNTNAP2,SEC14L5,HDAC9,DOCK2,CNNM1,LRRC23,LRRC17,EPHB1,FGFR3,CAMSAP1,HPGDS,LPAR4,KCNJ5,AFF1,AFDN,TAGLN3,MYO7A,P2RY13,CNOT4,NOVA1,OMG,CDK18,SERPINI1,EPN1,LRP12,PPP5C,MAPK7,MAPK8,PTAFR,ZNF493,ZMAT4,TRIM68,KLHDC8A,SLC9A5,SLCO1A2,ZNF415,UNC5B,CRTC1,TIMP4,TRPC1,UBE3A,WIPF1,MKRN3" Drug 4171_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "BEGAIN,APC,SEMA4G,N4BP2L1,CFLAR,BAIAP3,CAMK2B,LDB2,INA,CDH2,ADGRG1,CSF1,ARHGEF10,CNTNAP2,DAPK1,CTIF,BRINP1,HP1BP3,EDN1,ELAVL3,C3orf18,F5,FGFR3,AFF2,DCTN2,SORBS1,TBR1,OGA,GABRA2,GNAL,GNAO1,GRIK5,GUCY1A2,MID1,NPR2,NTRK3,OPCML,PLCD1,PPP5C,MAPK7,PTPRB,KLHDC8A,EMID1,PKNOX2,SLC8A1,SLC11A1,OGDHL,NMNAT2,PEG10,PHLDB1,ACSBG1,AMOT,SLC17A7" Drug 2945_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "FAM131A,PDE8B,KIF1A,CACNG1,HAP1,HIP1R,ARHGAP33,TAOK2,SLIT2,ABCG1,SPOCK2,MFAP3L,EFNB3,TNK2,LRRC23,FER,BAIAP2,ALDH1L1,GPR19,STON1,PADI2,TJAP1,KCND3,LAMA2,ADAM22,NRCAM,PCDH9,PDE1B,PDPK1,NECAB2,ZCWPW1,SEC61A2,ZFHX4,TCP11L1,SEC14L1,RPH3A,SLC6A8,SLC11A1,SHANK2,MYH15,WDTC1,ZHX3,SPTAN1,LHPP,TCF7L2,ZNF34,TNNT1,TNS1,RBFOX2,KCNE5,FLRT1,GDPD5,FZD3" Drug 2479_DN Tiabendazole [148-79-8]; Down 200; 19.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,NDRG3,NDRG2,BRAP,MTUS1,GAS7,NCOA1,CACNA1A,HIP1R,CD86,RAB28,CLCN3,CLCN4,CREM,SH2B1,CNNM1,CELSR3,PIPOX,PDLIM5,CELF1,GABRA2,INPP5K,SRCAP,PADI2,JAK2,SCAMP5,NF1,OGG1,PRKCZ,PTK2,PTPRN2,RAB3IL1,RAD51D,RAD52,RGS10,MYH14,SBF1,DOCK10,ZCCHC24,IZUMO4,KIF1B,JMJD6,ATP11A,ADGRL3,ZEB1,ICAM5,TLR4,TRPS1,LMF1,XRCC4,ZNF74,EMSY,TIGD6" Drug 3197_UP Furosemide [54-31-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "AMPD3,OGT,CDC14B,ARHGDIG,PLA2G4C,ZSCAN18,CA4,CACNA1A,CBFA2T2,ASIC3,CHN2,B4GALT6,AKAP5,SUSD5,RASSF2,DAPK1,SPOCK2,HEPH,MFAP3L,RUSC2,DYNC1I1,DTNA,ECM2,FLNC,HBS1L,SIGLEC8,INPP5K,GPD2,TDRKH,GRIN1,GRIN2C,GSN,HRH3,HLF,SYNPO,KPNA5,MAPT,MDFI,MEF2C,MOBP,SLCO1C1,OPCML,PDE1C,PDE4A,RYR1,SLC1A7,SLCO1A2,SORCS3,SYT11,PIK3R5,TPM2,SCG2,ITM2C" Drug 5304_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG3,NME5,AMPD2,BIN1,APLP1,ASPH,ALDH4A1,ATM,STX16,ATP6V0A1,BTRC,KYAT1,SRSF11,FOXN3,VAX2,HOMER3,SH2B1,MICAL2,EDRF1,PARD6A,FCF1,IRAK4,FGFR1,STAG2,NCKAP1,CACFD1,ATXN2L,MIA2,MPP2,SLC25A23,LRP12,TNPO2,PRKAR1B,PRODH,RASA3,SGK1,CHD9,SLC20A2,CDK5RAP2,WDTC1,SPTAN1,THSD1,FCHO1,VPS13A,ATP11A,TACC1,TRIM2,ARHGEF12,TMOD1,ZMYND8,SEMA3B,MPPE1,ZNF248" Drug 4805_DN Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RBM10,ABHD6,AP2A2,AP1B1,LTBP4,BIN1,ARRB2,PDE8B,MARK4,ALDH4A1,ATM,CFLAR,SCAPER,HAP1,LHX2,CREM,SH2B1,DCAF8,MED24,ATN1,EDNRA,PLXNC1,FECH,FGFR1,CAMSAP1,GPR153,AHDC1,DHX35,MAP4,NOS1,NRGN,PACSIN1,FSD1,PEX5,ZCWPW1,MAPK12,ITSN1,ABLIM3,SMARCA4,KIF13A,IQSEC2,KANK1,ARC,ROBO3,PCDHGA10,ZNF34,TSN,UBTF,LMF1,EVI5,HPS4,SEMA3B,SSPN" Drug 3201_UP Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "KIDINS220,NME5,APLP1,DDO,ARHGDIG,PTCH2,NRP2,BAIAP3,CBFA2T2,ARHGAP33,B4GALT6,AKAP5,CREB5,NCOR2,HDAC4,DAPK3,CTIF,DRD1,ING4,EFS,ACSL4,FGF1,AGAP2,GAD2,NEU3,GLYR1,RAPGEF4,GRM7,HAS2,PTGDR2,JAK2,KPNA5,MYO7A,NEFM,PLTP,PPP1R1A,GDPD2,SCN2B,ASAP3,SLA,SLC6A8,SLC9A5,SYT11,SYN2,PCDHGB6,CRTC1,AMACR,TRPC3,VAV2,XRCC4,SCG2,SEMA3B,SLC17A7" Drug 2398_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG3,AP2A2,CDC42BPA,APAF1,APBB2,PDE8B,ALDH4A1,SLC4A4,CALB2,MAP7,RUNX1T1,USP2,CBFA2T2,ARHGAP33,CHGB,CHN1,ZFYVE9,NMT2,SNPH,SPOCK3,EIF1,PDLIM5,PRELID3A,ERAP1,ADAMTS8,IL1RAPL1,AP4S1,KLF12,IL6R,KCNJ5,KCNK1,CD200,NF1,NUMA1,PBX1,PDE3B,PLCL1,PPP2R2B,PTAFR,PTCH1,FBXW7,KCNIP1,FERMT1,SLC20A2,CXXC4,SS18,PDLIM2,CRTC1,ZNF34,TPM1,AMACR,EMSY,ADAMTS9" Drug 3995_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NME5,AK2,APBB2,GAS7,APP,PDE8B,ALDH7A1,SYNJ2,MAP7,CHN2,NRXN3,KIAA1549L,QKI,HOMER3,CPS1,AATK,CSNK1E,EDRF1,ARHGAP24,GIT2,DBT,LYPD1,EFNA3,EN2,MTSS1L,DENND4A,FGF1,FGFR1,FYN,GHR,JAK2,MN1,NDP,NUMA1,RETREG1,MAPK7,ZCWPW1,KIRREL1,FBXW7,PAQR6,MAPK12,FBXO11,ST6GAL1,TMCC1,EMC1,ARHGAP26,DDN,TROVE2,SS18,ARHGEF9,KIAA1107,BHLHB9,SSBP2" Drug 1423_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADD2,APBA2,APOC1,ARRB2,CAPRIN2,ATP2B2,CADM3,CAMK2G,ARHGEF2,CREM,CRMP1,ZNF337,SPOCK2,DCTN1,FEM1B,APH1A,ZMYND10,KAT8,FGFR1,PRKAG2,C1orf61,FOLR2,GAA,B4GALNT1,RUNDC3A,TDRKH,BTN2A1,MAN1B1,KIF5A,OCRL,OGG1,RETREG1,PLCB2,GON4L,PTN,CCDC25,PCMTD2,PAQR6,KCNIP1,ITSN1,FAM102A,EPN2,ELMO2,MAPKBP1,WDTC1,FNBP1,ZC4H2,WWC1,ZMAT3,CA14,HIRA,ZNF74,REEP1" Drug 4254_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,PLA2G6,AMPD3,KIF1A,ADAM23,CFLAR,BAIAP3,CFAP410,CACNA2D2,ARHGEF10,CNTNAP2,AK5,DYRK1A,CNNM1,EGFR,PLXNC1,C1orf61,AFF2,PRELID3A,CSPG5,FYB1,INPP5K,ALDH1L1,RUNDC3A,TXNL4A,GLYR1,GRIK2,HNMT,MAPT,NOVA2,PDE4B,PLXNB1,PPARA,GRAMD1C,ELOVL2,PTPRB,PTPRH,ZSCAN2,KANSL3,SNCA,KIF13A,RBM34,TSNAXIP1,IQSEC2,TROVE2,KIAA1107,ZMYND8,SPHK2,KCNAB1,PARP11,FAM13C,NUP214,TIGD6" Drug 3617_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,PLA2G6,LTBP4,EPB41L5,APLP1,PPFIA3,ASPH,MTMR2,PLEKHB1,HOMER3,CNTFR,GIT2,DMPK,TOM1,EGFR,SORBS3,ING4,DENND4A,NCALD,ZNF589,FOXG1,GSN,ELOVL5,KCNN2,KPNA5,KITLG,CNOT4,RETREG1,PLCD1,GON4L,PTHLH,ZSCAN32,PEX5,ZSCAN2,NKAIN1,FAM184A,RGS3,ZNF821,FAM214B,BTBD7,COA1,ZHX3,LHPP,CLSTN2,INKA2,MAPK8IP3,EXOC7,TBCEL,TNS2,TPM1,ZKSCAN5,VIPR2,SMIM8" Drug 6968_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASPHD1,SCAPER,GYG2,KYAT1,ARHGEF1,QKI,DOCK4,CTIF,DSCAM,RCAN1,EGR3,EIF5,ELAVL3,RRAGB,FAM198B,ZNF589,KIAA1109,FHL1,GAD1,INPP5K,MSL3,ELOVL5,INPP5B,SMAD1,MMP16,NOS1,NPR2,NUMA1,PDE3B,NLE1,RAB3IL1,GTDC1,MYH14,FNDC3A,BCAN,SYBU,CCDC88A,SLC22A4,RBM34,ZHX3,UNC5B,NXT2,FCHO1,VPS13A,MCF2L,TRIM2,CHST8,TMOD1,TPM1,TRH,MAP3K12,NAV2,ST7" Drug 6304_UP Nitrendipine [39562-70-4]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ALAD,AMH,ANK2,SHROOM2,KIF1A,ARHGEF2,TAOK2,RAB28,CLCN4,STOML1,AKAP6,COL9A2,AATK,SUSD5,PHF14,ARMCX2,PLEKHO1,DMTN,STX2,ABCA8,FYB1,GLRB,KCNMB4,CACFD1,IL6ST,KCNN1,VWA5A,MX1,NNAT,NPY,PDGFRA,MAPK10,SAMD9,CNTLN,PLPPR1,SUGCT,MYH14,TMEM206,FAIM2,KDM4B,TAB2,TROVE2,PHLDB1,ACSBG1,ZEB1,TPM1,CADM1,UGT8,LMF1,NT5M,EVI5,PHTF2,AAAS" Drug 6505_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABR,KIDINS220,BIN1,AMT,APC,FAM131A,PPFIA3,APP,CDC14B,SLC4A4,CFLAR,CDH8,CDH10,BAG4,CHD1L,MICAL2,CTNND2,EDRF1,ZNF337,DBN1,RABGAP1L,MED12,TRAPPC9,CNNM1,EGFR,COQ7,PRKAG2,SEMA4D,GPR153,INPP5K,NUDT21,DIPK1A,KCNF1,VWA5A,LYRM9,ZNF862,OCRL,PCDH9,RGS12,TRAPPC13,BCAN,ABLIM3,SLC6A8,BTBD7,SLC20A2,RBM34,EMC1,TROVE2,SS18,EXOC7,CLDND1,ZNF74,ACTR3B" Drug 6019_UP Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ACHE,ACTN2,LTBP4,BEGAIN,APBB2,APP,CBFA2T2,NEURL1,CDH8,SOCS6,CHM,EPS15L1,TMEM59L,DSCAM,ST8SIA3,COQ7,ERBB2,ERCC2,TUBB4A,FGF1,FHL1,ALDH1L1,SRCAP,GNAO1,PRDM5,TJAP1,KCNH2,KCNJ5,MID1,AFDN,MOBP,NOVA2,NPTX2,NTRK2,PDE3B,PFKFB2,RAB3A,WLS,SCN8A,ASAP3,SYBU,SLC22A4,FAIM2,EMC1,HECW1,UNC5B,ZEB1,PCDHGB6,VAV2,TFIP11,SYNC,UBE3B,NUP214" Drug 3341_UP Reserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ARID1A,NDRG2,GAS7,APOC1,DNAH17,ZSCAN18,CACNA2D1,CALB2,CDH10,CHN2,TPP1,NRG2,NECTIN3,NCOR2,CSF1R,RIMS2,CTIF,SGK2,HIPK3,C3orf18,ERBB4,F3,FAM198B,ZIC4,KIAA1109,FHL1,SORBS1,GAD1,DISC1,RND1,TDRKH,PCLO,GRIK5,PRDM5,BCO1,NF1,NNAT,OMG,STRN3,PACSIN1,RAD52,KHDRBS2,TRIM68,RPS6KA2,SATB1,NTNG1,SNCA,SOX10,JMJD6,WSCD1,OBSL1,LAT2,PLSCR4" Drug 5595_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,ADCY2,NME5,BIN1,CACNA2D2,ZFYVE9,QKI,SLC4A7,CHD1L,AATK,CNTNAP2,GREB1,SEC14L5,RASSF2,ARMCX2,SV2B,NTM,ECM2,DYRK1A,MBNL2,EGR3,VPS13B,CAMKK2,OGA,TRAF3IP2,GLYR1,NXPH3,JAK2,KCNK2,MAPT,NELL2,NOVA2,OPRL1,PDE1C,PIK3R1,PLCL1,LRP12,MAPK10,KCTD17,TCP11L1,RASA3,SGK1,CPEB3,CCDC88A,COA1,MYH15,SNCA,SPP1,POPDC3,ATP11A,R3HDM1,FAM155A,UBE3A" Drug 7349_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "SRPX,BEGAIN,SEMA4G,ATP6V0A1,CFLAR,GYG2,FADS2,QKI,DMPK,DSCAM,DTNA,DTNB,MAMLD1,EFNA3,LRRC23,MTSS1L,EZH1,F3,FHL1,ERAP1,SRCAP,MALT1,RUNDC3A,TXNL4A,GPER1,CACFD1,ELOVL5,IGSF1,NDUFA5,NF1,PIK3R1,RETREG1,POU3F2,GON4L,RIPOR1,TRAPPC13,SBF1,SUPT20H,SYBU,SMARCD3,RBM34,WDTC1,KDM4C,SPTAN1,FAM168A,ARHGEF9,ARC,KIAA0930,ZNF34,TK2,LILRA4,TRPC1,SSPN" Drug 4621_UP Niridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "LTBP4,ASCL1,KIF1A,GYG2,CACNA1G,THSD7A,SOCS6,WHRN,PDE4DIP,CTNND2,C2CD2L,PLPPR4,DRP2,EDNRA,AASS,LPAR6,EIF5,PLEKHO1,EPB41,EFS,FAM198B,GAP43,ERAP1,GNG4,LPAR4,GRM2,GUCY1A2,GPR45,KCNA2,KCND3,LSS,TAGLN3,NF1,MAPK4,FAM120C,RASGRF1,GAL3ST4,NEK11,SEMA6D,NLGN1,ANKRD6,PPP4R3A,ARHGAP26,PHLDB1,SYT11,ARC,THBS4,TRH,VAV2,VGF,VIPR2,ZIC3,HRASLS" Drug 482_UP celecoxib; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ALK,APBB1,PDXK,RASL11B,BMP7,SYNJ2,MTMR3,BTRC,HOMER3,PCYT1B,IFFO1,HAPLN1,SDC3,INTS1,DYRK1A,E2F5,TNK2,BSCL2,RASL12,OLFM1,GABRG2,CYP46A1,LUZP2,LILRA2,AP4S1,RASSF8,PADI2,MAN1B1,ATXN2L,KCNJ5,MSR1,NNAT,SETD4,PDE3B,GPR173,LRP12,LRRN3,MAPK8,RAP1GAP,NUDT11,ATXN7,DOCK10,SLA,SPART,ARHGEF9,TCF4,SATB2,ZEB1,TRPC1,RPRM,KCNK12,EVI5,VPS35L" Drug 3067_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABAT,ASIC1,AMPH,APC,EPB41L5,PLA2G4C,DNAH17,CACNA1I,BAIAP3,REPS2,TAOK2,SLIT2,SLC24A2,DNAJB5,CNTNAP2,EDRF1,RIPOR2,FRMPD4,SV2B,SV2A,CDON,ABCC9,EFNB3,SUGP2,NCALD,CAMSAP1,ALDH1L1,ZNF276,GLRB,GPM6B,ADAMTS13,ELOVL5,ITPKA,KIF5C,MGAT3,GIT1,OMG,MTRF1L,MAPK7,RAB3A,GAL3ST4,RGS3,ZFHX4,SH3BGR,FRMPD1,ASAP3,SNCA,NPAS3,CLSTN2,ACSBG1,PCDHA5,FAM155A,VGF" Drug 5723_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADD2,ADRA1D,AP2A2,APC,PPFIA3,ASCL1,SLC4A4,ADGRB2,BMP7,SCAPER,GYG2,BTRC,CAMK2B,CDC42,DCLK1,PLEKHB1,CNTN1,CRMP1,RIPOR2,SRGAP3,PLXNC1,IRAK4,EN2,IGSF6,ZNF391,CDKL3,GABRA2,KCNN1,KIT,VWA5A,MMP16,CD200,DDX25,NF1,PALM,PIK3R1,MTRF1L,PILRA,PTAFR,PTPRB,TCP11L1,SLC1A7,SLC8A1,HECW1,SPTAN1,JMJD6,SEMA4A,TBCEL,SZT2,PIK3R5,RPRM,SLC17A7,KCNAB1" Drug 266_DN (+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ANK2,APBB2,ARSF,ATM,SLC4A4,CADM3,KALRN,CAMK2A,CAMK2B,ARHGAP33,CHN2,CLCN3,SULT4A1,CSF1,CHD5,ARHGEF4,KLHL3,DYRK1A,FAM13A,LPAR6,ELAVL4,EFS,CDKL3,EYA1,CACNG2,OLFM1,FOLR2,PDLIM5,NSG1,GRIN1,GRM2,ADAMTS6,ATXN2L,VSIG4,C2orf72,MOBP,MYO7A,PALM,EPN1,MASP1,C1orf109,MARCH1,ENOX1,RASGRF1,GAL3ST4,SLC15A2,NMNAT2,UNC5B,TROVE2,ZFR2,ANKRD12,SEZ6L,VIPR2" Drug 7270_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADCY6,AMPD3,BIN1,SEMA4G,ARRB2,N4BP2L1,SCARB1,SRSF11,SOCS6,PLEKHB1,CLCN4,HINFP,NCOR2,CNTNAP2,EDRF1,ARHGAP32,DCAF8,GIT2,MFAP3L,SMG7,PLEKHO1,VPS13B,LRRC23,EFEMP1,ATP8A1,FGF13,FGFR1,FOXG1,ZNF274,USP19,GPD1,HLF,TJAP1,KIF5C,LIG4,NASP,FA2H,PRKAR1B,KLK6,SH3TC2,ROGDI,RGS10,SMARCD3,KDM4B,R3HDM1,PARD3,HIRA,WNT7A,XRCC4,MAP3K12,HPS4,PHTF2,ACTR3B" Drug 6520_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "LTBP4,MRTFA,KCNAB2,APOC1,ARHGDIG,ATP1A2,ATP2B2,CADM3,RGS11,RUNX1T1,ADGRG1,CHI3L2,QKI,CSF1,GREB1,RASSF2,SPOCK2,ARMCX2,TRAPPC9,DTNA,SORBS3,ERCC2,DLC1,FGFR1,OGA,GALC,C1QL1,SOX21,ITIH2,KCNJ5,MAOB,PDE4D,PHKG1,MTRF1L,CCDC40,ZMAT4,RGS3,RGS12,GSTCD,TCP11L1,RPS6KA2,SEMA6D,MRAS,COA1,SMARCD3,RIMS1,HECW1,ARHGAP26,PHLDB1,PCDHGA10,VIPR2,ZNF711,SEMA3B" Drug 4952_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,ADORA1,AK2,PPFIA3,MARK4,ASPH,PTCH2,SCAPER,GYG2,FADS2,HOMER3,TCEAL2,EDRF1,SPOCK2,TMCC2,SGK2,SIDT2,HSD17B14,APC2,FABP7,KIAA1109,CAMSAP1,GABRA4,GPER1,PCLO,ITIH2,KCNMA1,MAP2,AFDN,MOBP,MX1,NDUFA5,CNOT4,PCBP3,OMG,OPRL1,KCNK10,RETREG1,PPARA,RAB3IL1,KHDRBS2,ZFHX4,TCP11L1,SLC9A5,COA1,FAIM2,CDK19,SYT11,LILRA4,UBE3A,XRCC4,ITM2C,SENP7" Drug 4556_UP Paroxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABAT,ACTN2,MTUS1,MRTFA,GAS7,PPP4R4,CDK13,AZGP1,LDLRAD4,CACNA1D,BRSK2,NEURL1,TAOK2,DNAJB5,CSF1R,EDRF1,DAPK3,EDN3,EDNRA,SGK2,SEMA3D,ING4,OLFM1,AFF2,FYB1,RUNDC3A,GPM6B,GPR22,GRIK5,PADI2,KIF5C,AFDN,MYCN,LYRM9,NEUROD1,NF1,PDE4D,PENK,PLP1,SLA,SLC2A5,SNCA,SPTB,SYP,TRIM2,ICAM5,TLR4,R3HDM1,TPM2,TRPC1,TUBB1,SCG2,TIGD6" Drug 6689_UP Biotin [58-85-5]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADCY6,APBB2,APC,ARHGDIG,ATP2B2,BMPR1B,SCAPER,CACNA1D,CHN2,CLCN4,QKI,COL9A2,IFFO1,CRMP1,HAPLN1,MICAL2,HP1BP3,LYPD1,DSCAM,DTNB,DUSP9,EDIL3,EDN3,EDNRB,HIPK3,EFNA3,MBNL2,EPB41,F5,REEP2,OLFM1,DKK3,ATF7,GRM8,KCNJ4,MDM4,POU3F2,PRKAR1B,MAPK8,ZMAT4,RNASEL,DZIP1,EMC1,TROVE2,TACR1,DOCK9,AP4E1,TPM3,NSD2,ZNF24,ZNF225,EVI5,JPH3" Drug 5214_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,MRTFA,BIN1,APP,PLA2G4C,ATP6V0A1,CA4,RUNX1T1,LHX2,EPS15L1,VCAN,RIMS2,SMG7,CDON,DRD1,ST8SIA3,SGK2,MBNL2,MTSS1L,PIPOX,CEND1,KIAA1109,GAB1,INPP5K,GLYR1,GRIK5,GSN,ICA1,KCNN1,MBD1,TAGLN3,NEUROD1,NEUROD2,PCDH8,CEP41,MAPK8,PTHLH,CRTAC1,RGS10,SH3BP2,SH3GL3,DOCK10,SLC2A5,ZKSCAN3,SNCA,KDM4C,SYN2,EXOC7,CHST5,AMACR,FAM155A,XRCC4,PRDM2" Drug 6458_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NDRG2,BEGAIN,CDC42BPA,GAS7,PDE8B,SCAPER,CACNB2,CBFA2T2,CLGN,CHRNA4,CHRNB2,CLCN4,HOMER3,AKAP7,WHRN,CYBB,ARHGAP24,SPOCK2,MFAP3L,HS3ST2,ATN1,ELAVL3,AGAP2,FYB1,ZNF44,HBS1L,GALC,USP19,GPM6B,ITPKB,SMAD1,MSI1,ADAM22,NEFM,OPCML,LRP12,MAGEL2,GDPD2,PTAFR,PTCH1,PTPRB,KCTD17,KLHL11,TCP11L1,PPP4R3A,COA1,PLCB1,PCDHA5,DICER1,XRCC4,SLC30A3,EMSY,KCNAB1" Drug 6742_UP Carbachol [51-83-2]; Up 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "SYN3,NME5,C1QTNF3,SEMA6A,ALK,APOC1,CFAP410,CACNA2D2,CSF1R,CTIF,SPOCK3,DSCAM,DTNA,EDIL3,HIPK3,NRN1,KIAA1109,FGF1,FGFR1,FOXG1,ALDH1L1,CSDC2,PRUNE2,ELOVL5,KCND3,KCNH1,MX1,NCAM1,CLDN11,PCSK2,PDE3B,PHKG1,LRRN3,PTPRB,CCDC40,ZMAT4,GSTCD,TCP11L1,ZFP30,CNKSR2,ANKRD6,SLC1A7,SHANK2,SLCO1A2,SNCA,HIF3A,TK2,TNS1,RUNDC3B,ZMYND8,EPM2A,CAMK1G,DPF3" Drug 2176_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "SYN3,BIN1,BMP7,CDK5R1,GYG2,CFAP410,CBFA2T2,DLGAP2,TAOK2,SLIT2,COL9A3,CSNK1E,SIPA1L1,PDE4DIP,DZIP3,EDRF1,SPOCK2,CTIF,MFAP3L,TRAPPC9,MBNL2,ELAVL2,EPB41L1,TUBB4A,ATP8A1,AGAP2,IQCG,SIGLEC8,GATM,ADAM28,PCSK1N,GRM1,GRM7,KIFC3,MAP4,MEF2C,ADAM22,MYCN,CNOT4,OPCML,SLC25A23,PPP2R2B,MAPK7,BEND5,SLN,SYN2,TRPC1,BEST1,XRCC4,ZBTB38,ZBTB16,SLC17A7,KCNAB1" Drug 2424_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ACTN2,ANK3,FGD2,KIF1A,ADGRB1,KSR1,ARHGEF7,CACNA1G,CFAP410,REPS2,LARGE1,CACNA2D2,CHN2,ZFYVE9,CREM,ABCG1,PDE4DIP,DZIP3,SMG7,DTNB,SRPK3,EPHB1,DLC1,FGFR1,C1orf61,PRELID3A,GAP43,RND1,GLI2,GLYR1,TDRKH,GRM7,KCNJ5,MPP2,MYCN,MYO6,MYT1,NEFM,NTRK2,OPRL1,CAMKV,FA2H,PTPN13,ZFHX4,SEMA6D,SH3BGR,SHANK2,KDM4B,ATP10B,ZFPM2,AP4E1,ZNF711,DPF3" Drug 2336_UP Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABAT,SYT13,AMPD3,ARNTL,NUMB,BMP7,SCAPER,CAMK2B,SLC25A14,ZFYVE9,SLITRK5,G3BP2,RABGAP1L,ABI2,COQ7,NCALD,CDKL3,ST3GAL6,PRKAG2,CAMSAP1,CAP2,SMC2,PDLIM5,CELF1,GPR153,ALDH1L1,ATF7,IL6R,KCNF1,KCNMA1,MAP4,SCAMP5,NF1,P2RY1,NLE1,MINDY2,PRKCZ,PAQR6,RASA3,KDM4B,CAND2,RBM26,ARHGEF9,ATP11A,DNMBP,TCF7L2,SZT2,CHST8,SSBP2,HIRA,VGF,VSNL1,SPHK2" Drug 4185_UP Probenecid [57-66-9]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NR0B1,KCNAB2,APC,CDK10,ZSCAN18,BACH1,BCHE,NRP2,GYG2,CACNA2D1,SCARB1,NEURL1,DNAJB5,CRY2,DTNA,USH1C,HIPK3,EFNA3,IRAK4,COQ7,ZNF589,KIAA1109,HBS1L,B4GALNT1,TOX3,GPR17,STON1,MCHR1,HNMT,AFDN,MOBP,NTRK2,PDGFRA,ENPP2,PRKCB,ELOVL2,GAL3ST4,RNASEL,SUPT20H,ZFP30,DZIP1,SNCA,TNIK,TROVE2,ACSBG1,COBL,ATP11A,TBCEL,TNS1,TPM1,NSD2,WNK1,PRDM2" Drug 6323_UP Cefoperazone dihydrate; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ASIC1,PPFIA3,CDK13,NRP2,SYNJ2,BTRC,CACNA2D1,IFFO1,CRMP1,ABCG1,CSNK1E,CNNM1,EFNA3,PLXNC1,IRAK4,COQ7,RRAGB,TESK2,KAT8,ZNF589,BAIAP2,HPCAL4,FOXG1,PRELID3A,DENND2A,GAP43,GATM,PTGDR2,HNMT,NUMA1,PFKFB2,CCSER2,STRN3,CNNM2,PTPRD,RAB3IL1,ATG16L1,SCN8A,IL17RB,SH3BP2,PEX26,CCDC88A,BTBD7,SNCA,LHPP,TROVE2,SS18,MLC1,TACR1,TK2,TNS1,NT5M,UBE3B" Drug 5083_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ARID1A,CDC42BPA,PPFIA3,ALDH4A1,BTRC,CLCN4,SLITRK5,DZIP3,DCAF4,ARHGAP32,ARHGAP24,RUSC2,DPH1,EDIL3,EFNA3,ETV1,RRAGB,B4GALNT1,COPS8,CNTRL,NR3C1,MUM1,BACH2,DIPK1A,KIF5C,PAK3,PDE4D,PLCD1,SNRK,WDR25,ATG16L1,SUGCT,ZFP30,SMARCD3,TMCC1,PDZD2,TNIK,EMC1,SPTAN1,COLGALT2,CEP68,VAMP1,ARHGEF12,CRTC1,GPR161,TK2,TNS1,TPM2,CADM1,UBE2H,UBTF,SPHK2,MAP3K12" Drug 4529_UP Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "NME5,GAS7,ASCL1,DNAH17,ZSCAN18,NOL4,CACNA2D1,CHI3L2,RAB26,NCOR2,CSF1R,DNAJC6,MFAP3L,DTNA,SGK2,FAM13A,ING4,TNK2,F5,FGFR1,FGFR3,FLT1,SORBS1,FYB1,SYT17,ALDH1L1,GNG3,PRUNE2,PTGDR2,ATXN2L,KIF5C,MAPT,MBD1,MDFI,MYL3,NCAM1,FA2H,GRAMD1C,KHDRBS2,RGS7,GSTCD,TMEM206,FOXRED2,SCN3A,MRAS,ZNF415,BEX1,ACSBG1,PCDHGB6,ZKSCAN5,VLDLR,KCNAB1,MVB12B" Drug 2241_UP Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADD2,AP2A2,NR0B1,LTBP4,AMH,BIN1,APOC1,ATP1A2,ALDH7A1,TPP1,HOMER3,TENM4,CHD5,DCAF4,DOCK4,RASSF2,DCT,RUSC2,MBNL2,EGR3,NRN1,DLC1,FGFR1,FHL1,FLNC,GNAL,PRUNE2,GPM6B,RAPGEF4,KLF12,C2orf72,ITIH2,KCNH2,MOBP,ADAM22,BCO1,ZNF862,MYT1,NEFM,NF1,P2RY1,PLCD1,PLP1,CDIP1,TNPO2,LRRN3,MAPK7,VPS13C,ST6GAL1,SLA,SLC2A5,WSCD1,SLC30A3" Drug 5592_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ACTN1,DOC2A,AMH,GAS7,ARRB1,BRINP2,RASL11B,ADGRB1,CFLAR,CA4,CLDN10,CCKBR,CBFA2T2,CLGN,ADGRG1,CLU,NCOR2,NOS1AP,DCT,DRD1,ING4,CEND1,TUBB4A,FHL1,RUNDC3A,GRM7,GRM8,TJAP1,IL6R,MAP2,MID1,ADAM22,NF1,TMOD2,KCTD15,PLCB2,LRP12,KCTD17,TTLL7,MYH14,CPEB3,SLC9A5,KDM4B,SS18,PLCB1,TAL1,DMXL2,TRIM2,TEX15,CHST5,VIPR2,LAT2,XRCC4" Drug 4621_DN Niridazole [61-57-4]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "MADD,PDE8B,ASTN1,BTRC,CAMK2B,SYNGR3,TAOK2,NMT2,ABCG2,SLC4A8,VCAN,CTNND2,FAM131B,DBT,EGFR,MRNIP,ERCC2,FGFR1,FOXG1,AFF2,ZNF44,SEPT9,C1QL1,MSL3,GPM6B,GPR37,GRIK2,CACFD1,IFI16,MGAT3,MX1,NEK1,PAK3,GON4L,PTN,ZSCAN32,FAT4,RGS10,FBXW7,AP1AR,ASAP3,SLC1A7,CCDC88A,SLC20A2,TMCC1,TSNAXIP1,SPTAN1,ARHGEF9,SMG6,EVI5,SEMA3B,ST7,SMIM8" Drug 2971_UP Procarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "GAS7,NCOA1,MAP7,ZFYVE9,CLCN4,SULT4A1,HOMER3,AKAP7,CLOCK,CSNK1E,VCAN,DOCK4,CTIF,ST8SIA3,FAM13A,MRNIP,ENO2,RASGRP2,EPS8,FER,CAP2,ADAM28,POLL,GPM6A,STON1,PCLO,BTN2A1,ITPKA,LSS,AFDN,NPR2,PDE4D,CCSER2,PLCL1,PLEC,CNNM2,PTCH1,RGS3,PBRM1,MYH14,ST6GAL1,ARHGEF40,DBNDD2,SPTB,ATP11A,TCF7L2,SYNE1,PSD3,OBSL1,TNS1,RBFOX2,PLPPR2,ZBTB38" Drug 3483_DN Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "MRTFA,APBB2,BCAS1,PPFIA3,ARRB2,BMP7,CFAP410,CAMK2G,FAM189A2,HOMER3,CRY2,LYPD1,SGSM2,DSCAM,DTNA,LRRC23,STX2,ZNF589,FHL1,SEMA4D,PRELID3A,CGREF1,SEPT9,INPP5K,GLYR1,CNTRL,KHK,MAP4,OGDH,PDE3B,RETREG1,MBOAT7,MAPK8,ELOVL2,PEX5,RGS10,DCUN1D2,FBXO11,LIMCH1,ZBTB43,THSD1,ELOVL4,ATP11A,ANKRD12,SEMA4A,TCF7,SIK3,BEX4,ZKSCAN5,VAV2,LMF1,MAP3K12,MPPE1" Drug 7401_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADRA1D,ALAD,MRTFA,ADAM15,BACH1,ADGRB2,FGF17,KALRN,P2RX6,NEURL1,TCEAL2,VCAN,CNTNAP2,ARHGEF4,EXOG,DRP2,ST8SIA3,IRAK4,ING4,FGF13,SORBS1,OGA,FYB1,GAD2,ERAP1,INPP5K,GLYR1,GNG3,GRIK5,GRM1,HSD17B1,KIF5C,LMO2,PDE4D,PMP2,PRKAR1B,SAMD9,ZCWPW1,ARHGEF10L,NEK11,MAPK12,ZFP30,AMBRA1,ST6GAL1,KANSL3,SPTAN1,COLGALT2,TMEM121,TRO,HIRA,VIPR2,SLC17A7,KCNAB1" Drug 1537_DN Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "MRTFA,ALDH4A1,SLC4A4,CAMK2G,KRIT1,SLIT2,ZFYVE9,SULT4A1,AKAP7,SH2B1,CSNK1E,ARHGEF4,DAPK3,SMG7,OPTN,ING4,EML1,VPS26C,SCML2,FGFR1,OGA,ZNF276,GLYR1,CACFD1,NDUFA5,PRKAR1B,PTCH1,ATG16L1,GTDC1,NEK11,TCP11L1,SUPT20H,AMBRA1,SLC1A7,ELMO2,EFHD1,FNBP1,POGZ,ST5,ARC,SEMA4A,AHCYL2,BHLHB9,RBFOX2,METTL3,CADM1,PLPPR2,VIPR2,REEP1,TFIP11,MARCH8,PHTF2,ZNF248" Drug 4096_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ABAT,BEGAIN,PPFIA4,DDO,CACNA2D1,DGKI,NRXN3,CLCN4,STOML1,CSF1,CSF1R,MICAL2,IPCEF1,PPP1R16B,CTNND2,ST18,C2CD2L,SPOCK3,RABGAP1L,DSCAM,SIDT2,ING4,SRPK3,DCTN2,PRELID3A,GABRA2,SIGLEC8,GFER,PCDH17,GNAL,GNG4,GRIN1,KCNB1,KCNQ3,TM6SF1,AFDN,NF1,SLCO1C1,ENPP2,PLCD1,PPP2R2B,PROX1,PTPRB,RFX2,RPS6KA2,ZNF334,SNCA,TPM3,TRO,UCHL1,VAV2,HRASLS,NUP214" Drug 5389_DN Ganciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "RALGAPA1,ASPHD1,APLP1,BRINP2,SCARB1,SOCS6,SH2B1,CRY2,NCOR1,TRAPPC9,CNNM1,EFNA3,SORBS3,IRAK4,EPB41L1,ZNF589,FHL1,IQCG,MPP6,RUNDC3A,GNG4,GPR19,SPACA9,GRIK5,ATXN2L,HNMT,INPP5B,MAP4,MPP2,PLXNB1,PRKAR1B,PRPH,TMEM104,RAD52,ZFP30,SLC1A7,EPN2,ZSWIM8,FCHO1,MAPK8IP3,CEP68,PLCB1,ATP11A,KAZN,SEMA4A,TCF7,CABIN1,PLPPR2,VAV2,EMSY,GDPD5,HPS4,RNF170" Drug 3990_UP Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "ADAM23,SCAPER,MAP7,CBS,PLEKHB1,TPP1,AKAP7,IFFO1,CSF1R,CSNK1E,ATRNL1,EDNRA,HIPK3,EFNB3,TNK2,COQ7,ETV1,KIAA1109,TRMO,GAB1,GNG4,GPER1,GRIK5,GRM2,GRM3,KCNJ9,TM6SF1,MX1,PENK,PIK3CD,MTRF1L,LRRN3,PKN2,ELOVL2,PTPRB,PTPRN2,FAM120C,ACSS3,BEND5,RET,KCNIP1,FOXRED2,DOCK10,CNKSR2,PREX2,ZNF334,SYT5,CRTC1,TMOD1,LMF1,ZNF24,WNK1,DPF3" Drug 6640_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.58E-05 1.00E+00 5.60E-04 6.37E-03 53 198 "KIDINS220,CACNA1D,KRIT1,INA,CD86,CLCN4,ENTPD4,VCAN,PDE4DIP,USP6NL,CHRDL1,NR1D2,HIPK3,SEMA3D,EFNA3,AASS,ZNF391,EXTL1,FGF1,FGFR1,DCTN2,FYB1,ALDH1L1,GNG4,GSTM5,KLF12,KCNN1,TM6SF1,AFF1,MMP16,ZNF862,PCDH9,MED1,PROX1,PRPH,WDR25,PTN,TMEM231,IL17RB,SH3BP2,SLC1A7,SLC2A5,BEX1,SPTB,CDK19,PHLDB1,PLCB1,TACR1,SLC44A1,LILRA4,AMACR,LAT2,DPF3" Drug 1112_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.70E-05 1.00E+00 5.73E-04 6.52E-03 49 179 "ABHD6,ADD3,ALAD,ARNTL,BMP7,ST3GAL5,RAB29,CBFA2T2,AKAP12,KIAA0513,RIMS3,GIT2,DNAJC6,TSPAN5,OPTN,EFNB3,MBNL2,STX2,EXTL2,TAOK3,FYN,GLS,RAB40B,RNFT2,PADI2,KIF5C,MXI1,NEK1,FA2H,PKIA,PRPH,SEC14L1,SH3BGR,SH3GL3,PPM1E,WDR47,ELMO2,KDM4B,SPTAN1,ELOVL4,RGL1,STXBP1,TACC1,TRIM2,HEY1,NPL,SSBP2,UBE2H,DNAJC12" Drug CID000001456 OD-q Stitch 4.70E-05 1.00E+00 5.73E-04 6.52E-03 49 179 "ASIC2,ACTN1,ADCY5,ADCY6,ADCY8,ADD3,ALDH7A1,CACNA2D1,NGB,ARHGEF1,LRBA,ASIC3,CHRM1,LRIG1,EDN1,CALCRL,KCNMB2,CRCP,KCNMB4,GNAS,GRIK1,SOX21,GUCY1A2,GUCY1A1,GUCY1B1,HBA1,KCNC1,KCNC2,KCNMA1,KCNN1,KCNN3,MARK3,MEF2C,NOS1,NPPA,NPR2,P2RY1,PDE1C,PDE2A,CDK14,PRKACB,MAPK3,MAPK12,SOX5,SOX11,MLC1,TAC1,ARHGEF12,VIPR2" Drug 2753_UP Syrosingopine [84-36-6]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.70E-05 1.00E+00 5.73E-04 6.52E-03 49 179 "ASIC1,LTBP4,PPFIA1,PPFIA3,APP,MARK4,N4BP2L1,ST3GAL5,SYNGR3,ARHGEF2,CLGN,RAB26,ARMC8,SLC4A7,MFAP3L,DTNA,OPTN,EFNB3,MBNL2,RGS17,HSD17B14,ENO2,STX2,AMOTL2,SRCAP,TDRKH,GRB10,KCNH2,KIF5C,SLC11A2,NUMA1,PIK3CD,FA2H,PRPH,TMEM231,ZFHX4,ZNF821,SH3BP2,ARHGEF40,ZCCHC24,KDM3A,TRIM2,TK2,BEX4,WBP2,MICAL1,VLDLR,SLC30A3,PRDM2" Drug CID005361323 Gabrene Stitch 4.86E-05 1.00E+00 5.93E-04 6.75E-03 17 40 "ABAT,PDXK,QKI,DRD1,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD2,PTCH1,MLST8" Drug CID000001242 SKF 38393 Stitch 4.89E-05 1.00E+00 5.96E-04 6.78E-03 34 110 "ABAT,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,LRBA,CHRM1,QKI,CREM,DRD1,EEF1A2,CELSR3,PPP1R1B,GAD1,GAD2,ARPP21,GNAS,GRK4,GRIK1,GRIN2C,GRIN2D,HRH3,HTR2A,NPY,PDYN,PENK,PRKACB,SST,TAC1,MLST8,ZNF106,TRH" Drug CID000005056 "trans-3,4,5-trihydroxystilbene" Stitch 4.92E-05 1.00E+00 6.00E-04 6.83E-03 132 608 "ADORA3,PLA2G6,APAF1,APOC1,APOC2,API5,APP,ASCL1,BCS1L,BID,CFLAR,NGB,AIFM1,CD86,CDC27,CDC42,FOXN3,PLEKHB1,CHRNA4,ABCG2,COX4I1,NCOR1,NCOR2,ABCG1,EDRF1,RIPOR2,LYPD1,GSDME,DYRK1A,ABCC9,EDN1,EBI3,EGFR,TUBD1,ENO2,ERBB2,F3,FABP7,TUBB3,TUBB4A,FGFR1,UBE2E3,FOXG1,FOXO3,FLT1,AK8,FYN,ZNF44,ATP8A2,TUBA8,SESN1,PPARGC1A,TUBA1C,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,GUCY1A2,GUCY1A1,GUCY1B1,HBA1,TNFAIP8L3,HPCA,IGF1,IL12A,TUBB2B,ASPRV1,MAP4,MATK,IL17D,MEF2C,MITF,NFE2L2,NFIX,NOS1,NPR2,PC,PDCD2,PIK3C2A,ANLN,PIK3CD,PIK3R1,PPARA,PPP3CA,PPP3CC,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,PTPRG,PTPRN2,RASGRF1,ARID4A,GSTCD,FBXW7,S100B,SAFB,MAPK12,MYO18A,SLA,SIRT2,APOM,ABCC8,SYT1,TAF9,TCF12,TNS2,SIRT1,CABIN1,TNS1,PIK3R5,TUBB1,ZBTB16,PRDM2,TUBA1A,NETO1" Drug ctd:D012110 Reserpine CTD 4.95E-05 1.00E+00 6.03E-04 6.86E-03 36 119 "ADRA1D,ADRB2,RGS9,CHGA,CHGB,CHRM1,ABCG2,CNR1,CREM,DRD1,ERBB2,FABP7,GAD1,GNAO1,GNAS,NR3C1,GRM5,KCND2,KCND3,KCNH2,NOS1,NPY,NTRK2,PCSK1,PCSK2,PENK,ABCB1,RET,RGS4,RGS10,SNCA,ARC,TAC1,RASD2,VGF,SCG2" Drug CID000001003 phosphate Stitch 5.02E-05 1.00E+00 6.12E-04 6.96E-03 328 1716 "ABR,ACLY,TKTL1,KDM5D,KLRC4,ADCY5,ADCY6,ADCY8,BRAP,CDC7,ADORA1,ADRA1B,AP2A1,AP2A2,AP1B1,NME5,AK2,ARHGAP20,AMPD2,AMPD3,OGT,PPFIA1,DGKZ,DGKD,NT5C3B,PPFIA3,CDC14B,PDXK,ARHGDIA,ARRB1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,ATP6V0A1,BARD1,BCHE,BLM,SYNJ1,SYNJ2,MTMR3,MTMR2,AP1M1,GYG2,CA4,CACNA1E,CALM1,CAMK2D,CARS,CBS,KYAT1,CCNH,CCNT1,ENTPD2,ENTPD6,DGKI,LRBA,CDC25B,CDC42,TIGD7,COPB2,CHN1,CHN2,CHRM1,PLEKHB1,CNOT8,ARHGAP22,MYL6B,CLTA,CLTB,CLTC,NGEF,PCYT1B,COL4A5,CPS1,ENTPD4,GDA,ABCG1,CRYM,CS,SEC24C,CSNK1E,CSNK1G3,PLCXD3,ARHGAP32,ARHGAP24,EARS2,DGKB,DGKG,DAPK3,IP6K1,SIRPA,RHOBTB1,AK5,DMD,DNM1,DNM2,DTNB,DUSP9,DNM1L,EDN1,EDN3,EEF1A2,TMTC1,FAM13A,EGFR,RASA4,EIF4G1,EIF5,TUBD1,ENO2,EPB41,ERCC2,KATNAL1,F3,F8,TUBA1B,TUBB3,TUBB4A,ATP8A1,PPP1R1B,FECH,SEC24B,ATP5PD,IP6K2,VTI1B,SLC37A3,FOLH1,AK8,ATP6V1H,ATP2C1,GAB1,GAP43,MTHFD2,INPP5K,ACSS1,GART,GATM,GCK,TUBA8,CYP46A1,GFER,GGT7,GGT5,GK,DBF4,GLS,GLUL,GNAL,GNAS,GPD1,GPD2,TUBA1C,PLCD4,GRM1,GSN,PTPN5,MAP4K5,GYG1,HBA1,GPR45,TNFAIP8L3,ARHGAP36,HP,HPR,HSP90AA1,IDH3A,IDH3B,MYLK2,IGF1,INPP1,TUBB2B,ITPKA,ITPKB,KCNJ3,KHK,LIMS1,ARHGAP12,MAP2,MAPT,MAT2A,MBP,MTR,MYBPC1,MYH3,MYH6,MYL3,NBL1,NDUFA5,NEFM,NEFH,NME4,OCRL,OGDH,OGG1,P2RY1,PAH,PC,PDCD2,PDE2A,ENPP2,PDPK1,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,ABCB1,DUSP26,PHKG1,PKM,PLCB2,PLCD1,PLEC,PLIN1,SLC25A23,POLR2F,PPM1B,PPP1R1A,PPP2R2B,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CB,PPP3CC,PPP5C,PRKACB,PRKCB,PRKCG,PKN2,MAPK3,MAPK4,MAPK7,PSMA6,PTAFR,PTHLH,PTH1R,PTPN13,PTPRB,PTPRD,PTPRE,PTPRG,PTPRN,PTPRN2,PTPRO,PTPRZ1,PYGM,ACSS3,RASGRF1,RDX,DUSP15,RGS3,RNASE1,NUDT11,RPE,RPL15,UEVLD,ATP8B4,RPL38,RPS20,RYR1,RYR3,SALL1,SARS,SCN2A,COPZ1,RASA3,PPM1E,RPH3A,SLC6A7,SEPHS1,SIRT2,SCMH1,SLC20A2,SLCO1A2,SLIT1,ARFGAP1,NAXD,SOX2,KIF21B,SPP1,ARHGAP26,SST,ADHFE1,ACSBG1,FGD4,SUPT5H,ARHGEF9,PLCB1,SYN2,ATP11A,TAF6,TAF9,SIRT1,TIAM1,TK2,TMOD1,TNNT1,RBFOX2,NPL,TPM3,TPM4,TRH,TRIO,NEIL2,NTSR2,TUB,TUBB2A,TUBB1,PLPPR2,VAV1,VAV2,SLC13A3,SPHK2,PLPPR5,CA10,PRTFDC1,TUBA1A,SLC17A7,PLD4,SLC17A6,EPM2A" Drug 2231_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.03E-05 1.00E+00 6.12E-04 6.96E-03 51 189 "NME5,AK2,ALK,FAM131A,ATM,CADM3,ADGRB2,CFLAR,MTMR2,LDLRAD4,BTRC,CFAP410,GREB1,RASSF2,MAML1,RABGAP1L,DMPK,DRD1,ATN1,EFNB3,MBNL2,IRAK4,SPEG,DLC1,FGF1,OGA,ZNF44,ERAP1,ALDH1L1,NR3C1,IL6ST,KCNJ5,MAP4,ADAM22,PALM,PAX6,PCDH9,PTAFR,ASAP3,CPEB3,SLCO1A2,MAPK8IP3,JMJD6,ATP11A,TGFBR3,R3HDM1,ZMYND8,CA14,UBE3A,WNK1,ITM2C" Drug 835_UP carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.03E-05 1.00E+00 6.12E-04 6.96E-03 51 189 "ARID1A,AMPD3,CDC42BPA,APLP1,AQP4,ALDH4A1,CAMK2B,SLC16A4,SCARB1,CRLF1,TPP1,CNTFR,FAM149A,PDE4DIP,BRINP1,TOM1,F3,ATP8A1,IQCG,DPYSL4,NR3C1,MAP4K5,IRAK3,RASSF8,ATXN2L,MGAT3,ADAM22,NPTX1,PCDH9,PIK3CD,EPN1,MINDY2,PPP1R1A,MAPK8,RAB3IL1,ATG16L1,C1orf54,GTDC1,SH3BGR,FNDC3A,LIMCH1,PEG10,ZNF423,TSPYL2,CEP68,STX1A,TRIM2,DICER1,TRIO,EPM2A,ZNF248" Drug 3823_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.03E-05 1.00E+00 6.12E-04 6.96E-03 51 189 "ABAT,ALAD,APC,ASCL1,MARCH3,CADM3,N4BP2L1,ADGRB2,ADGRB3,BAIAP3,TMEM257,CHN2,CLU,CSF1R,PDE4DIP,SMG7,DLG4,MBNL2,CEND1,KIAA1109,BAIAP2,ATP8A2,RND1,GLYR1,RAB30,GLS,GNAL,PRUNE2,GRIN1,GRM7,PADI2,KCNJ5,VWA5A,KITLG,SERPINI1,RAB3A,RFX2,RGS3,SLC1A6,MAPK8IP3,ACSBG1,VAMP1,WASHC4,PCDHGA10,AHCYL2,TMOD1,TNS1,TRIM9,PRDM2,SLC17A7,MVB12B" Drug 4688_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.03E-05 1.00E+00 6.12E-04 6.96E-03 51 189 "NME5,SRPX,AMPH,GAS7,KSR1,SCAPER,BSN,CACNA2D2,RCBTB2,TPP1,FADS2,PDE4DIP,CTH,KIAA0513,DAPK3,EIF4G2,ING4,BAIAP2,KHDRBS3,ERAP1,GLS,TDRKH,PCLO,NR3C1,LMO2,MAP2,MDM4,AFF1,CNOT4,OPCML,PDE4B,SERPINI1,PLCD1,SLC25A23,SMIM7,PMP2,PTH1R,C1orf54,TCP11L1,SMARCD3,ZNF415,ZCCHC24,CLSTN2,SAMSN1,CEP68,PLCB1,CHST8,TUBB1,SLC30A3,PRDM2,SSPN" Drug 5455_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.03E-05 1.00E+00 6.12E-04 6.96E-03 51 189 "DPF1,CACNA1D,CHN2,JAM2,CLCN4,CPS1,MFAP3L,DLG2,DTNA,DUSP9,HIPK3,SORBS3,FAM198B,SCML2,ATP8A1,FGF1,GLS,PRUNE2,KCNJ5,KIT,MAOB,MAP4,MITF,MOBP,NF1,PDE3B,PFKFB2,PPP2R2B,MAPK10,SAMD9,VPS13C,RAD52,SH3BP2,FAM214B,ARHGEF40,SLCO1A2,ZCCHC24,ARHGAP26,ATP11A,TNS1,TRIO,TRO,FAM155A,UCHL1,VSNL1,WIPF1,SLC30A3,DNALI1,PRDM10,SLC17A7,KCNAB1" Drug CID000000312 chloride Stitch 5.10E-05 1.00E+00 6.21E-04 7.06E-03 208 1029 "SYN3,ASIC2,ACHE,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,SLC12A5,ADORA1,ADORA2A,ADRA1D,ADRA1B,ADRB2,AP2A1,AP2A2,AGT,PHF12,APOC2,AQP4,AQP6,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,BARD1,BCHE,HCN2,BCS1L,BID,SYNJ2,CA4,CA8,CA12,CACNA1B,CACNA2D1,CACNB2,CACNB4,CALM1,CAMK2D,CBR1,CBS,KYAT1,CCK,SLC5A11,CD38,LRBA,CDO1,NUMBL,CHM,CHRM1,SLC22A6,CLCN3,CLCN4,TPP1,CNR1,SLC4A7,SLC4A8,COX4I1,CP,CPS1,CRY2,SLC32A1,CSNK1G3,BOC,EARS2,DAPK3,DBI,DCT,DCTN1,DMPK,SLC29A4,SLC12A6,DRD1,DYRK1A,EDN1,CELSR3,EGFR,ENO2,DMTN,EPHA5,GPHN,F3,PTK2B,PRMT5,ACTL6B,POLK,FOLH1,PDLIM5,PNMA2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,JPH4,GALR1,ACSS1,DNER,GGT7,GGT5,GLRB,AIFM3,POLL,GPT2,TDRKH,GRID1,GRIK1,GRM1,GSTM5,HBA1,GPR45,HTR2A,HTR5A,IDH3A,IFI16,KCNMA1,KCNN3,MAOB,MAT2A,MATK,AQP11,MID1,MSRA,DDX25,MTR,NBL1,NPPA,NPR2,P2RX7,P2RY1,PAH,PDPK1,BEST3,ABCB1,PKD1,FXYD1,PMP2,PTPA,PRKACB,MAPK10,SLC26A11,PRPSAP2,PTAFR,PTK2,PTPRB,PTPRG,PTPRN2,PTPRO,SLC6A15,RGS7,RNASE1,PBRM1,RPL15,SCN2A,SCNN1D,FOXRED1,ASRGL1,SLC1A2,SLC1A3,SLC4A3,SLC1A6,SLC1A7,SLC6A1,SLC6A7,SLC6A9,SLC6A11,RADIL,SIRT2,SLC9A5,SHANK2,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SCMH1,SLC20A2,RIMS1,SNAP25,SST,VPS13A,SYT1,TAC1,TAC3,TACR1,PDLIM2,TF,ACTR6,RBFOX2,NPL,TPM3,TMPRSS5,CA14,TTPA,WRN,KCNT2,POLR3H,WNK1,SLC17A7,WNK3,WNK2,SLC17A6,MSRB3" Drug 5695_UP S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC2,ADCY2,ADORA1,ADRA1D,SEMA6A,LTBP4,MRTFA,SLC4A4,AZGP1,MTMR7,DNAJB5,CABP1,PDE4DIP,RIPOR2,DCC,DCT,MAGI2,ST8SIA3,SGK2,EGFR,ETV1,ATP8A1,FGF1,AGAP2,SORBS1,LYVE1,GPR37,GRM8,HAS2,IFI16,KCNN1,LMO1,VWA5A,MDFI,NTRK2,PHKG1,PIK3CD,MAPK8,SATB1,SLC2A5,KANSL3,SLC11A1,EPB41L3,AJAP1,SYP,TCF4,PSD3,AHCYL2,TK2,VLDLR,SPHK2,PARP11" Drug 5776_DN Hexestrol [84-16-2]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ADCY6,ALAD,BIN1,PPFIA3,MARCH3,NUMB,ATM,ALDH7A1,CDK5R1,SYNJ2,SCAPER,CHN2,PLEKHB1,HAPLN1,CSF1,CNTNAP2,ARHGAP24,ZFYVE16,GIT2,DBT,RHOBTB1,TMCC2,FEM1B,ETV1,FGF13,AHDC1,GNAS,NR3C1,GUCY1B1,KIF2A,ODF2,CLDN11,FSD1,GON4L,PTN,PTPRN2,PEX5,TMEM231,MYH14,RPS6KA2,ASAP3,RAB3GAP1,LIMCH1,ELOVL4,CEP68,PHLDB1,JMJD6,HIRA,UGT8,WNT7A,NDRG4,KCNAB1" Drug 2377_UP Indomethacin [53-86-1]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "BIN1,PDXK,ARRB1,ARRB2,ASCL1,ASPH,ATP2B2,MYOM1,MYRF,LARGE1,TAOK2,SLIT2,CRMP1,DGKG,SPOCK2,DTNA,MBNL2,EIF4G2,ELN,EFS,PIPOX,GRM1,ICA1,IGSF1,KCNJ5,KIT,MBP,NF1,SLCO1C1,CNOT4,NPPA,PBX1,PDE4A,PACSIN1,CNNM2,LRRC49,ACSM5,FAT4,RGS3,HUNK,GALNT10,PPM1E,SLC1A6,FAM214B,SLC6A8,MAPK8IP3,SEPT8,KAZN,ROBO3,TNS1,CHST5,FLRT2" Drug 6730_UP Rolipram [61413-54-5]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "AP2A2,AGT,PPP4R4,CDK13,MTMR3,CALB2,CAMK2A,CAMK2B,MAP7,CD86,CDC42,CACNA2D2,CHRNA4,TBC1D5,DCC,MFAP3L,DMPK,DUSP9,PLXNC1,TENM1,F5,AFF2,PCDH17,RAB30,GNAL,SPACA9,PTGDR2,HLF,ELOVL5,MX1,NDP,NF1,NFYA,NPR2,NTRK2,PALM,MAPK8,DCHS2,ENOX1,SEC61A2,GSTCD,ST6GAL1,DOP1A,TNIK,TBCEL,TBL1X,PCDHGA10,TK2,TPM3,WNK1,PRDM10,EPM2A" Drug 1805_UP Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "KIDINS220,KCNAB2,GAS7,ARNTL,NCOA1,KIF1A,SYNJ2,MTMR2,C5,CFAP410,ZMYM4,ZFYVE9,CHD1L,CSF1,GPRASP1,KIAA0513,DBT,C2CD2L,RCAN1,HPCAL4,ZMYND11,ARFIP1,COPS8,MSL3,POLL,GPD2,GPR17,EML4,IPO5,MDFI,CNOT4,SPATA6,SAMD9,FAM120C,TTLL7,CCDC25,NEK11,ST6GAL1,SLC1A3,SLC4A3,ZHX3,KDM4C,UNC5B,SS18,ATP11A,TRIM2,PSD3,ARHGEF12,TIAM1,PIK3R5,HIRA,ZBTB14" Drug 896_UP 5152487; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "BIN1,APAF1,APBA2,CDC14B,CDK13,ATP2B2,B3GALT2,BCL2L2,BAIAP3,LDLRAD4,BTRC,CA4,CAMK2B,ARHGEF1,CDH2,HOMER3,TENM4,ARHGEF4,TBC1D5,CELSR3,COQ7,FHL1,IQCG,DPYSL4,PDLIM5,AHDC1,TOX3,GNG4,LPAR4,CNTRL,IFI16,LMO2,MAP4,AFDN,NUMA1,KHDRBS2,RPS6KA2,SCN2B,FNDC3A,ZNF365,RBM34,KDM4C,CLSTN2,INKA2,CEP68,KIAA1107,TNS2,CHST8,AP4E1,SMUG1,KCNK12,UBE3B" Drug 4275_DN Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC1,ATM,NRP2,CFLAR,MYRF,BAIAP3,CFAP410,CBFA2T2,PLEKHB1,CPS1,CRMP1,KLHL3,PARD6A,DNM2,HIPK3,PLEKHO1,COQ7,LRRC23,ERCC2,PTK2B,DLC1,TRMO,ZNF276,POLL,SHISAL1,INPP5B,KCNN1,KIF5C,MAPT,LYRM9,NTRK2,RETREG1,BCAS3,RGS10,RPS6KA2,DOCK10,ST6GAL1,SLC4A3,FAM214B,SNCA,BEX1,LHPP,MAPK8IP3,ASTN2,CRTC1,GPR161,SLC44A1,CBX5,TNS1,TRIO,TFIP11,HPS4" Drug 3680_UP Halcinonide [3093-35-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC2,NME5,CDC14B,ASPA,SLC2A11,NRP2,CDK5R2,CACNA1D,CACNA2D1,CAMK2B,NEURL1,CHN2,SLC24A2,COL9A2,AKAP12,ERC2,ARHGEF4,SPOCK2,HEPH,HS3ST2,EGFR,CDKL3,ETV1,NRN1,KIAA1109,FGFR3,GNAL,GPM6A,GRK4,GRIA4,GRIK5,NXPH3,IL6R,JAK2,LYRM9,NF1,LRRN3,PID1,MYH15,HECW1,ZC3H13,SSTR2,INKA2,MLC1,MCF2L,HEY1,TNS1,TRPC1,HIRA,NAV2,SLC17A7,KCNAB1" Drug 3100_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ADD2,AP2A2,ANK3,APBB2,CDC14B,ALDH4A1,MYOM1,NRP2,CACNA1I,THSD7A,INA,CBFA2T2,REPS2,CREM,CSF1,RIPOR2,PHYHIP,DAPK3,C2CD2L,DNM2,EFNA3,FAM13A,EGFR,OLIG2,FHL1,PRELID3A,CGREF1,HPGDS,ADAMTS13,GRM2,PADI2,KLF12,SCIN,ITPKA,MAP4,GIT1,MYO7A,KCNK10,TREM2,PENK,PIK3R1,RAD52,WLS,SLC9A5,SLCO1A2,IZUMO4,DDN,ST5,TBCEL,PSD3,HPS4,SLC17A7" Drug 7187_UP Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC1,ABHD6,AK2,PLA2G6,APC,PPP4R4,CFLAR,MTMR3,C5,SRSF11,ZFYVE9,STOML1,SLC4A7,AKAP12,FAM169A,GIT2,JAKMIP2,LYPD1,RCAN1,DTNA,MBNL2,IRAK4,KIAA1109,PRELID3A,ERAP1,NR3C1,MAP2,MMP16,MPP2,NF1,SLC11A2,MAPK7,PRODH,DCUN1D2,SYBU,ANKRD6,SLC1A7,PPP4R3A,TTC17,ZSWIM8,SS18,NSFL1C,PLCB1,ATP11A,KIAA0930,TPD52,ZMYND8,CLDND1,ZBTB14,SYNC,MARCH8,SSPN" Drug 3838_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "AP2A2,PLA2G6,AMPH,KCNAB2,APLP1,RASL11B,CAMK2B,SLC16A4,NEURL1,CLCN4,FADS2,PICK1,CNTFR,CNTN1,PCYT1B,CSF1,PLCH2,RIMS3,CTIF,MFAP3L,DNM1,DYNC1I1,ATN1,DYRK1A,EDNRB,EN2,OLFM1,AFF2,DCTN2,C1QL1,RUNDC3A,GPER1,HTR2A,IFI16,KCNB1,KCNF1,KCNN1,ADAM22,NOVA2,SLC11A2,PLCB2,PNMA3,PKNOX2,ZKSCAN3,RBM34,ARC,TBCEL,WSCD1,PIK3R5,FLRT2,SPHK2,SLC30A3" Drug 3606_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "NDRG2,MTUS1,APC,EPB41L5,APLP1,ASPH,ATM,CFLAR,BMP7,CDC27,ARHGAP33,ZFYVE9,RCHY1,ENTPD4,EDRF1,DAPK3,DTNA,HIPK3,PHF20L1,F3,FGF12,FGFR1,GPD2,GSN,DHX35,MDM4,KITLG,NF1,PCDH9,SYTL2,PTHLH,RGS10,RGS12,SLC25A36,FNDC3A,RPH3A,PPP4R3A,ZCCHC24,TACC1,TBCEL,IQCE,KIAA0930,TCF7L2,TRIM2,TMPO,ZMYND8,HIRA,UBE2H,HPS4,MPPE1,KAT6A,PHTF2" Drug 2477_DN Etifenin [63245-28-3]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "NDRG2,BRAP,AP2A2,GAS7,CDK10,ADAM15,CDC27,SRSF11,CHM,EPS15L1,RAB33A,CSF1,DOCK4,SMG7,ABI2,KIAA1109,FGFR1,IQCG,CAMKK2,CELF1,POLL,ATXN2L,IFI16,MAP4,MDM4,NCAM1,NEK1,NUMA1,PLCD1,PTN,ATG16L1,ATXN1,ZNF821,MRAS,FAM214B,WDTC1,DOK5,RBM26,TROVE2,SS18,KANK1,CAMSAP2,KIAA1107,WWC1,SZT2,ICAM5,KAT6B,XRCC4,SYNC,ZNF225,WNK1,UBE3B" Drug 2682_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "MTUS1,ANK3,ARRB1,ATP2B3,CACNA1G,CAMK2A,MAP7,CDC42,CDO1,CLGN,CHRNB2,HOMER3,CREM,PDE4DIP,CNTNAP2,RIMS2,DCAF4,SNPH,DGKG,ATN1,DTNA,EDN3,REEP2,BAIAP2,FHL1,C1orf61,GAD2,RND1,RAPGEF1,GRIK2,ATXN2L,OMG,PFKFB2,NLE1,BCAS3,FAT4,GAL3ST4,KCTD17,MAP6D1,RPS20,SALL1,NTNG1,LIMS2,ZCCHC24,IZUMO4,INKA2,TMEM121,ZNF34,TIAM1,TRPS1,ZNF225,EVI5" Drug 5077_UP Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASPHD1,ACHE,ADORA2A,PLA2G6,AMPD3,GAS7,ASTN1,N4BP2L1,RGS9,KSR1,BMPR1B,IL33,ENTPD2,CDH8,WHRN,CALY,CTNND2,SPOCK3,HS3ST2,DRP2,COQ7,RASGRP2,PIPOX,ARMCX1,SIGLEC8,ATF7,LPAR4,GPER1,KLF12,ITIH2,KCND3,PACRG,MATK,MATN3,NEUROD1,SLCO1C1,NUMA1,PALM,PPARA,GRAMD1C,PROX1,MASP1,PTPRH,RFX2,RGS7,TCP11L1,RTN1,FOXRED2,SLN,PHLDB1,ADGRL3,DOCK9" Drug 4642_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ADCY6,AP2A2,BEGAIN,CDK10,SOCS6,RAB28,STOML1,QKI,CREM,CSF1,CNTNAP2,DBT,C2CD2L,EXOG,EDNRA,SIDT2,EFNA3,EIF5,EPB41L1,EFS,VPS26C,C1orf61,PDLIM5,FYB1,FYN,SYT17,GPM6B,STON1,GPER1,ITPKA,NEFM,NPTX1,PDE4D,RETREG1,TNPO2,SNRK,PTK2,TMEM231,CLIP1,FNDC3A,URGCP,KANSL3,SLC14A1,TNIK,ARHGAP26,PHLDB1,COBL,TNS1,SSBP2,ZNF32,MVB12B,EPM2A" Drug 7051_UP Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC1,ADCY6,ADORA1,NME5,AK2,AMH,APOC1,APP,PDE8B,KIF1A,CA12,CAMK2B,CAMK2G,ARHGEF1,FAM189A2,IFFO1,INTS1,SPOCK2,C2CD2L,SRGAP3,LRRC17,KCNMB4,SPACA9,KCNB1,KCNMA1,MAP4,MN1,MOBP,NF1,NRGN,TMEM104,PYGM,GAL3ST4,RPS20,SBF1,SFPQ,SCG5,SLC2A5,PEX26,PPP4R3A,SHANK2,LIMCH1,WDTC1,CLSTN2,SAMSN1,JMJD6,EXOC7,ZMAT3,THBS4,LAT2,SLC30A3,SEMA3B" Drug 2258_UP Thalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ADCY6,ADRA1B,AP2A2,SYT13,AMH,ASTN1,CAMK2B,SULT4A1,WHRN,CPS1,NCOR2,CSF1R,RIMS2,KIAA0513,CNIH3,HIPK3,EFNB3,EIF4G2,KCNMB2,PIPOX,FABP7,FOXG1,PRELID3A,OGA,HBS1L,SEPT9,ADAM28,PRUNE2,NR3C1,MAP4,ADAM11,LRP1B,MYCN,PALM,PPP2R2B,PRKAR1B,GDPD2,CNTLN,PTHLH,SLC30A10,SELL,RASA3,CPEB3,SLC1A2,SLC14A1,ZEB1,TNS1,AMACR,TRPC1,VAV2,ADAMTS9,SLC17A7" Drug 4373_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASIC2,ADCY2,CDC42BPA,APAF1,KCNAB2,ARSE,CDK13,CAMK2B,HIP1R,NCOR2,SPOCK2,SPOCK3,HS3ST2,ATN1,DYRK1A,ST8SIA3,SGK2,KCNMB2,ERBB2,ZNF589,GAD2,GRM1,ITGA7,ITPKA,KCNJ5,MGAT3,MMP17,TAGLN3,PCBP3,CDK18,MED1,CEP41,RELN,RAD52,KHDRBS2,EMID1,KCNIP1,RYR1,SLC1A7,SNAP25,IZUMO4,ZC3H13,NCDN,SYP,SYNE1,DNAH7,ICAM5,TLL2,RIMBP2,HIRA,UGT8,LAT2" Drug 2743_DN Stachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ABHD6,AP2A2,APBB2,EPB41L5,PDE8B,ATM,ALDH7A1,ARHGEF7,RUNX1T1,ZFYVE9,QKI,DCAF4,HIPK3,EFNA3,MBNL2,KAT8,FGFR1,FHL1,SEMA4D,FAM49B,SEPT9,MALT1,GLS,MSL3,HNMT,TJAP1,INPP5B,ITIH2,MAP4,MMP16,NPR2,NPTX2,RETREG1,PLCD1,MBOAT7,PPP2R2B,PRKAR1B,RAD52,RGS10,TCP11L1,SH3BP2,AMBRA1,KDM4B,WDTC1,UNC5B,INKA2,STX1A,PLCB1,HIRA,DNALI1,ST7,SENP7" Drug 7413_UP Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "LTBP4,APBB2,ST3GAL5,BTRC,KYAT1,CCNT1,CRLF1,SULT4A1,NECTIN3,ENTPD4,HAPLN1,FEZ1,CTNND2,DCAF4,DCT,C2CD2L,ATN1,TOM1,HIPK3,FEM1B,OPTN,MBNL2,PLXNC1,COQ7,KIAA1109,FGFR1,BAIAP2,FYB1,LIG4,SMAD1,MAPT,NELL2,SLC11A2,SETD4,PDE3B,PIK3CD,PACSIN1,MAPK8,PLPPR1,RAB3A,MYH14,SEC14L1,FAM214B,ELMO2,MAPKBP1,ANKRD12,TCF7L2,AP4E1,TGFBR3,AMOT,VLDLR,MAP3K12" Drug 2886_DN Prenylamine lactate [69-43-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "APBB2,APOC1,ATP2A2,CDK5R1,SYNJ2,MTMR2,ASIC3,B4GALT6,VAX2,SOCS5,APPL1,DCAF4,RIMS3,LYPD1,PARD6A,SORBS3,ZNF589,FGFR3,DPYSL4,CINP,HBS1L,GALC,RAB30,INPP1,KCNH2,KCNJ3,KHK,KIF2A,MAPT,SCAMP5,MPP2,GIT1,OGDH,OPA1,PMP22,LRP12,MBOAT7,FA2H,MINDY2,RAB3A,FAM184A,RGS12,KDM4B,EMC1,SPART,KIAA0930,TCF7L2,RPGRIP1L,CDK20,CADM1,MICAL1,SMIM8" Drug 6208_UP Dienestrol [84-17-3]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "ASPHD1,AP2A2,AK2,SEMA6A,BIN1,CA12,ADGRG1,CLCN3,COL9A2,BAG4,MICAL2,DZIP3,DAPK3,MFAP3L,PARD6A,EGR3,ZNF589,GABRA2,GAD1,GLS,GPR19,TJAP1,IL11RA,INPP5B,KCNN1,MPP2,ZNF862,SERPINE2,SMOX,POLG,ELOVL2,FAM184A,ZDHHC14,RGS4,SGK1,ITSN1,SYBU,ABLIM3,SMTN,SLC20A2,LIMCH1,ATP11A,SEMA4A,TRIM2,ZNF34,FAM155A,VIPR2,MAP3K12,SEMA3B,MPPE1,MVB12B,ACTR3B" Drug 6242_UP Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "MRTFA,AMPH,GAS7,MARK4,ASPH,SLC4A4,ALDH7A1,CFLAR,SCAPER,BTRC,CBFA2T2,QKI,TCEAL2,ABCG1,RGS6,PDE4DIP,HDAC4,MFAP3L,RCAN1,SUGP2,FER,GABRA2,ALDH1L1,GLYR1,STMN2,SPACA9,TJAP1,INPP5B,KCND3,MAP4,ADAM22,NTRK2,RETREG1,ZCWPW1,PAQR6,SH3BP2,FRMPD1,SMTN,SAMSN1,MAPK8IP3,PLCB1,ASTN2,PCDHA5,ZMYND8,PLPPR2,VAV1,VGF,WIPF1,PRDM2,SLC17A7,ST7,NUP214" Drug 1868_UP Dapsone [80-08-0]; Up 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "MTUS1,AMT,APP,ARNTL,ADAM23,BMP7,SYNJ1,RUNX1T1,CBFA2T2,TAOK2,IQCK,CSF1,DAPK3,DBT,KIAA0753,SMG7,DLG4,HEYL,MRNIP,PLEKHO1,ZNF589,ANKFY1,AHDC1,GLYR1,GLS,LILRA2,ICA1,LIG4,MATK,GIT1,NEFH,CNOT4,PENK,RC3H2,MAPK7,MYH14,SATB1,ZNF821,FAM102A,FUZ,SLC1A7,SLC20A2,SLN,ZNF667,TSNAXIP1,ZEB1,ATP13A2,TNS1,RBFOX2,LMF1,XRCC4,PHTF2" Drug 2959_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.17E-05 1.00E+00 6.25E-04 7.11E-03 52 194 "KIDINS220,APC,RASL11B,ATP1A3,FUBP1,LDLRAD4,RUNX1T1,ENTPD6,ARHGAP33,SLIT2,NMT2,CSNK1E,RCAN1,FAM13A,PLEKHA1,LRRC23,CAMSAP1,C1orf61,AGAP2,ALDH1L1,RND1,RAPGEF1,ATXN2L,SCIN,KCNMA1,AFDN,GIT1,ADAM22,MYH3,NEFM,CCSER2,KCTD15,PLCL1,POU3F4,PKN2,PRKCZ,SBF1,ITSN1,SLC11A1,SHANK2,SNCA,SPTAN1,ZC4H2,ATP11A,EXOC7,PDLIM2,KAT6B,TNS1,RBFOX2,UBTF,LMF1,PRDM10" Drug ctd:C049985 staurosporine aglycone CTD 5.24E-05 1.00E+00 6.30E-04 7.17E-03 15 33 "NOG,CHRM1,GAD1,GAD2,GAP43,KCNC2,MT3,NEFM,NEFH,NTRK2,PDPK1,MAPK3,SYN1,SYP,TAC1" Drug CID000104916 CGS 8216 Stitch 5.24E-05 1.00E+00 6.30E-04 7.17E-03 15 33 "DBI,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MCHR1,SST,SSTR1,SSTR2" Drug 2820_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "KIAA1324,AK2,AMH,EPB41L5,PRX,PLA2G4C,PDE8B,ATM,SCAPER,CA4,CACNA2D2,ASIC3,CNOT8,AKAP7,WHRN,RCHY1,OSBPL3,RIMS2,DCAF4,NOS1AP,ARHGAP24,RASSF2,C2CD2L,TRAPPC9,LPAR6,ZNF589,KIAA1109,C1orf61,SEPT9,GRIN1,DHX35,ICA1,KCNQ3,NOVA2,POU3F4,PPP5C,CNNM2,RAB3A,RAB3IL1,RGS12,SHANK2,HECW1,CLSTN2,POPDC3,TCF7L2,CRTC1,CABIN1,TNS1,VIPR2,SLC13A3,ZNF154,SMIM8,TIGD6" Drug 7241_UP Mesalamine [89-57-6]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASPHD1,ASIC1,KDM5D,NDRG2,AMH,AMPH,ARRB1,ATP6V0A1,NRP2,SCAPER,GYG2,BTRC,CACNB2,ARHGEF2,SRSF11,CHM,STOML1,HAPLN1,RIMS2,CNNM1,DLC1,KAT8,HPCAL4,KHDRBS3,ZNF44,GAD2,GALC,POLL,GRM8,HNMT,KCND3,KCNMA1,LIFR,KITLG,MITF,RAB3A,FAM184A,RGS10,KCNIP1,SYBU,SLCO1A2,WDTC1,SYN2,SEMA4A,CRTC1,SLC44A1,TRH,AMACR,TRPC3,UBE3A,FLRT2,VIPR2,SSPN" Drug 6629_UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "KIDINS220,C1QTNF3,ALK,MRTFA,APAF1,DDO,BMPR1B,GYG2,CDC42,AKAP5,CTNND2,C2CD2L,EDIL3,IRAK4,COQ7,ZNF391,REEP2,ZMYND10,BAIAP2,DCTN2,FAM49B,PRELID3A,TMEM8B,GRIK2,KCNJ5,CTNNA3,CNOT4,PALM,PCDH9,PDE3B,PFKFB2,RETREG1,RAD51D,RGS7,KCTD17,TMEM206,CCDC102B,SELL,ASAP3,DOCK10,PPP4R3A,SLCO1A2,OGDHL,TNIK,PHLDB1,MCF2L,PCDHGA1,OBSL1,THRA,R3HDM1,CADM1,WNK1,DPF3" Drug 3676_DN Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADRA1D,C1QTNF1,C1QTNF3,MRTFA,AMPD2,APBB1,APC,CDC14B,MARK4,NUMB,SLC4A4,SCAPER,KYAT1,SYNGR3,CACNA2D2,ARHGAP22,EPS15L1,CLCN4,CNTFR,IQCK,SLITRK5,HDAC9,CNIH3,ANKMY1,C1QL1,SPACA9,ELOVL5,SHISAL1,TJAP1,KCNMA1,KHK,ODF2,PCDH9,PIK3R1,CNNM2,PTN,CCDC40,TTLL7,ROM1,DZIP1,PPP4R3A,SLN,TROVE2,VPS13A,ARC,KIAA1107,TIAM1,SMUG1,RPRM,NSD2,MAP3K12,PLSCR4,KAT6A" Drug 3096_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "CNTNAP1,FAM131A,CDC14B,CASK,PLA2G4C,RGS11,RUNX1T1,NEURL1,LARGE1,CHI3L2,ZFYVE9,CREM,ABCG1,SUSD5,EDRF1,DLG3,CDON,EFNA3,TNK2,RASGRP2,PRELID3A,GAD2,GNG3,GPM6B,HNMT,ITIH2,KCNJ5,KCNK1,MAP4,SCAMP5,NPPA,NTRK2,TMOD2,PFKFB4,PPARA,MAPK7,BCAS3,SYTL2,RAD52,RYR1,SCN2A,FRMPD1,SMTN,SLN,PALLD,IZUMO4,DDN,ARHGEF12,TRPC1,ZNF154,SH3GLB2,PCBP4,AP3B2" Drug 1424_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,C1QTNF3,AMT,APBA2,ATM,CADM3,MPDZ,SYNJ2,MTMR3,CACNB2,SLC25A14,RUNX1T1,FOXN3,CHRM4,BAG4,CREM,ENTPD4,ZNF337,SPOCK2,HP1BP3,PARD6A,BAIAP2,PRKAG2,ANKFY1,GLYR1,PTGDR2,MAN1B1,KCNB1,TAGLN3,NF1,OCRL,PALM,PDE3B,PPP2R2B,CCDC40,RAD51D,ARID4A,TCP11L1,NTNG1,FBXO11,SLC15A2,INTS9,ATP10B,STXBP1,SYT1,ANKRD12,MTCL1,TK2,CA14,TUB,FLRT1,ZNF74,DPF3" Drug 5773_DN Methacholine chloride [62-51-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "MTUS1,AMT,APLP1,PPFIA3,CDC14B,SEMA4G,MARCH3,ALDH4A1,SYNJ2,ARHGEF2,CREM,SDC3,ARHGAP24,C2CD2L,ING4,CDKL3,ATP8A1,FGFR1,CINP,HTATSF1,SHISAL1,KIF5C,NF1,NFIX,NUMA1,PBX1,PC,NLE1,PPP5C,PRPH,RALGDS,TTLL7,PAQR6,ZNF821,ASAP3,LIMS2,ZKSCAN3,SMARCA4,SMARCD3,TMCC1,WDTC1,KDM4C,PHLDB1,ARHGEF9,COBL,ARHGEF12,TMEM121,CABIN1,METTL3,PLPPR2,WIPF1,WNT7A,MAP3K12" Drug 3898_DN Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ARID1A,BIN1,MARK4,SYNJ2,SCAPER,BAIAP3,CA4,HIP1R,NEURL1,FOXN3,STOML1,SH2B1,CSF1R,RIMS2,CTIF,STX2,NCALD,ZNF589,SCARA3,FOXG1,GPR153,GCNT2,SRCAP,RUNDC3A,GNG3,GRM8,KHK,MATK,MID1,AFF1,NF1,RAB3IL1,FAT4,RGS10,MYH14,ROM1,PPP1R9A,FAM214B,PKNOX2,SNCA,WDTC1,SPTB,KIAA1107,WSCD1,TRIM2,DOCK9,THRA,HEY1,TK2,DAAM2,CABIN1,VIPR2,GDPD5" Drug 6353_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "GRAMD1B,AP2A2,EP400,APC,CLU,WHRN,ARHGAP32,INTS1,GIT2,ARMCX2,SPATA2,KIAA0753,DLG3,EPHA5,ERBB2,TUBB4A,SCML2,TRMO,CAMKK2,SRCAP,GPM6B,GRM1,GUCY1A1,MAN1B1,SYNPO,IL11RA,KIF2A,MAP4,ZNF862,CLDN11,PBX1,PC,PDGFRA,RAB3A,RGS10,NCBP3,CSRNP3,FUZ,KBTBD4,SMARCA4,DDN,SYT11,ARHGEF9,IQCE,WSCD1,TCF7L2,CABIN1,TNS1,TSC2,ZKSCAN5,XRCC4,SCG2,MPPE1" Drug 3389_UP Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "FZD9,ADORA1,ADORA2A,AP2A2,NME5,PLA2G6,ALCAM,KCNAB2,SLC4A4,LDLRAD4,CAMK2B,CDH8,VAX2,SULT4A1,AATK,ARHGEF10,VCAN,USP6NL,CNIH3,TMCC2,HSD17B14,ERCC2,PIPOX,SORBS1,RASL10A,GPR75,ATF7,NR3C1,NXPH3,ITGA7,KCNMA1,KCNN1,KIFC3,MOBP,MX1,NPTX2,EPN1,PLP1,LRP12,PPP5C,CEP41,SNRK,PLPPR1,PTPRH,ENOX1,WLS,ST6GAL1,CXXC4,SP4,HECW1,LMO3,CRTC1,VLDLR" Drug 3260_UP Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "TKTL1,ARID1A,ADORA2A,KIDINS220,PLA2G6,SEMA6A,LTBP4,MRTFA,CDC42BPA,ANK3,SEMA7A,APBB2,MARK4,ATP1A2,CACNA1I,NEURL1,CHRNB2,SULT4A1,WHRN,RIMS3,RUSC2,SHANK1,DTNA,OPTN,ELAVL3,SIGLEC8,CPLX2,RND1,RAB30,VWA5A,MID1,GIT1,ADAM22,MX1,NPY,NPPA,NUMA1,PDE3B,RETREG2,MAPK7,PTAFR,RAB3IL1,PNMA8A,FOXRED2,LIMCH1,INKA2,MAPK8IP3,VAMP1,SYN2,POPDC3,ZEB1,ZNF34,XRCC4" Drug 1386_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ARNTL,CDK13,MARCH3,ATM,MTMR9,CFLAR,BMP7,CAPN3,RUNX1T1,CHI3L2,CHN2,RAB26,AKAP6,ENTPD4,VCAN,PPP6R2,ZNF337,TM9SF4,DBI,DPH1,RCAN1,EEF1A2,ABI2,FGF1,BAIAP2,CAP2,CINP,GAP43,RUNDC3A,PCSK1N,GNG4,GPR12,HRH3,KHK,MAP4,GIT1,NTRK3,SETD4,PDE3B,PTPRE,CCDC40,ARID4A,RGS12,KBTBD4,SMARCA4,ZCCHC24,ZHX3,ZSWIM8,FCHO1,THRA,NACC2,XRCC4,EVI5" Drug 7287_UP Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ALAD,APP,PPP4R4,CDK13,MARCH3,DNAH17,BMP7,SCAPER,MAP7,CHRNB2,RAB26,HOMER3,PDE4DIP,CNTNAP2,DNAJC6,SPOCK3,AASS,ING4,ANKMY1,EZH1,FGFR1,FOXG1,TRMO,ZNF44,SRCAP,SPACA9,ATXN2L,ELOVL5,TJAP1,SCIN,INPP5B,KCNMA1,KHK,KIFC3,MIA2,RIPOR1,TMEM231,RALGDS,GTDC1,RGS10,SCG5,FNDC3A,ARHGEF40,SNCA,WDTC1,SOX15,IQSEC2,THSD1,SS18,TNS2,CRTC1,RPRM,DPF3" Drug 2495_UP Ethionamide [536-33-4]; Up 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "RALGAPA1,SYN3,SPARCL1,ALK,AMPH,PKP4,ATP6V0A1,KIF1A,GYG2,HIP1R,CDO1,CHRNA4,ARHGEF10,DZIP3,ARHGEF4,PHYHIP,PLPPR4,DLG3,DTNB,EDNRA,HIPK3,RASGRP2,ZNF549,AGAP2,KHDRBS3,DLL3,SIGLEC8,LILRA2,PCLO,GSN,AP4S1,KIFC3,LAMA2,TAGLN3,NAP1L2,NF1,NRCAM,GPR173,RFX2,TTLL7,PALLD,IZUMO4,INKA2,PHLDB1,KAZN,TRO,FAM155A,LMF1,SPHK2,REEP1,KCNAB1,KAT6A,SSPN" Drug 6682_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "KIDINS220,ALK,AMPD3,APAF1,GAS7,BRINP2,NRP2,MYRF,CACNB2,ARHGAP33,FOXN3,NRXN3,CLCN4,PDE4DIP,SPOCK3,CHRDL1,CELSR3,PLXNC1,MTSS1L,EPHA5,KIAA1109,HPCAL4,DCTN2,DPYSL4,SYT17,HLF,TJAP1,ITPKA,KIFC3,VWA5A,TM6SF1,GIT1,LYRM9,NDUFA5,NF1,NNAT,ODF2,PC,RGS10,TTLL7,RPS6KA2,PAQR6,IL17RB,ASAP3,CNKSR2,KANK1,JMJD6,SMG6,KLHL4,SZT2,CDK20,TPM2,REEP1" Drug 6093_DN Butamben [94-25-7]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AMT,APBB2,APOC1,PPFIA3,APP,ARHGDIG,PDE8B,ADAM23,CFLAR,SYNJ2,PLEKHB1,VAX2,PICK1,CSF1R,LRIG1,FEZ1,PDE4DIP,CNTNAP2,MFAP3L,RUSC2,TMCC2,KBTBD11,DRD1,ING4,MRNIP,C3orf18,F3,FER,FGF12,ALDH1L1,INPP5B,KCNF1,KCNMA1,LMO2,MSI1,NPR2,NUMA1,PDPK1,PLXNB1,MBOAT7,PRKAR1B,MAPK7,PRPH,ELOVL2,ATG16L1,SEMA6D,TTBK2,PLCB1,SYN2,PCDHA5,TIAM1,TPM1,ZNF45" Drug 4795_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ABHD6,ADD3,MTUS1,CDC42BPA,EP400,MAP4K3,EPB41L5,APOC1,ARNTL,ASPH,MTMR2,HAP1,LHX2,VAX2,SH2B1,SOCS5,TBC1D5,DBT,FBXL5,ATN1,DTNA,MAMLD1,EDNRA,EML1,CAMSAP1,PDLIM5,CAMKK2,CGREF1,ZMYND11,DHX35,JAK2,KCNJ3,MIA2,NRCAM,ODF2,PDE3B,STRN3,PTK2,ZDHHC14,KCTD17,ZNF821,LIMCH1,KIF13A,IQSEC2,SPART,ASTN2,SEMA4A,ROBO3,KIAA0930,TCF7L2,TMEM121,SYNC,TIGD6" Drug 4615_DN Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AMPD3,APP,ASTN1,STX16,ADGRB2,SYNJ2,SCAPER,CACNA1I,SCARB1,ARHGEF2,CNOT8,NMT2,QKI,IQCK,BRINP1,DLG3,MBNL2,SORBS3,MTSS1L,NOP56,GLYR1,HTATSF1,GRM1,NEK1,NFYA,OPCML,PLCD1,PRKAR1B,ZSCAN2,SH3TC2,FBXW7,RPS6KA2,FOXRED2,MAPK12,ATXN2,SH3BGR,ASAP3,SLA,ELMO2,BTBD7,IQSEC2,THSD1,SS18,TCF4,RIMBP2,RBFOX2,NSD2,ZBTB14,NDRG4,NT5M,MPPE1,SMIM8,RNF146" Drug 5742_DN Ethacrynic acid [58-54-8]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AP2A2,MTUS1,EP400,ARNTL,STX16,ADAM15,BCL2L2,SYNJ2,CLCN4,DNAJB5,BAG4,CRY2,SLITRK5,SIRPA,MFAP3L,ING4,TNK2,DENND4A,FER,FGFR1,CGREF1,MSL3,PRRC2B,DIDO1,MAN1B1,IFI16,MPP2,MT1M,NF1,PLCD1,PRPH,ELOVL2,RAB3IL1,GTDC1,RGS7,SEC61A2,RPS6KA2,IL17RB,ASAP3,SLC14A1,SNCA,TNIK,ZBTB43,SS18,KANK1,KLHL7,TCF4,KIAA0930,CHST8,ZMYND8,XRCC4,PRDM2,KAT6A" Drug 2496_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ABHD6,ADORA1,SRPX,MRTFA,ANK2,PKP4,PPFIA3,PDE8B,ALDH4A1,CCDC181,KIF1A,NRP2,KSR1,THSD7A,RAB26,FAM149A,WHRN,COL9A3,CREM,SNPH,KIAA0513,DLG3,RCAN1,EDNRA,RASGRP2,STX2,DLC1,FER,HPCAL4,FOXG1,C1orf61,SRCAP,RUNDC3A,ATF7,CACFD1,KIF3A,HTR2A,KCNMA1,BCO1,MYT1,PDGFRA,RELN,RASGRF1,FOXRED2,HECW1,SPART,CLSTN2,THSD1,KAZN,WSCD1,RPGRIP1L,ZBTB38,KCNAB1" Drug 2109_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "APP,MARK4,ADAM15,MPDZ,ST3GAL5,MYRF,KYAT1,REPS2,TBRG4,RCBTB2,HINFP,VCAN,SOCS5,PDE4DIP,KIAA0513,CNIH3,KLHL3,ABCC5,SIDT2,EGFR,SPEG,RACK1,ZNF589,GLUL,AGFG1,IFI16,SHISAL1,KHK,IPO5,MATN3,ODF2,PBX1,PPP3CC,MAPK7,BCAS3,GTDC1,ATXN1,PPP1R9A,ASAP3,ZC3H13,CAMTA2,SS18,NCDN,IQCE,TCF4,KIAA0930,AHCYL2,ZNF34,CABIN1,ZNF32,NDRG4,PDSS2,AAAS" Drug 6154_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ABHD6,KIDINS220,AMPD3,APC,RAB33A,CLCN4,AKAP7,IQCK,CRMP1,CRY2,EDRF1,RIMS3,DAPK1,DAPK3,TRAPPC9,DTNA,FCF1,CDKL3,PIPOX,GAA,SEPT9,ZNF276,GLYR1,GNG4,GPD2,DIDO1,GRIK5,GRM1,MAP4,MID1,MOBP,ZNF862,NPR2,CCSER2,RETREG1,PRKCZ,PTN,PEX5,RAD52,MAP6D1,FOXRED2,MRAS,ITSN1,ANKRD6,FAM214B,JMJD6,PSD3,AP4E1,PARD3,TNS1,SMUG1,ZIC3,KCNAB1" Drug 2287_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AMPD3,CDC42BPA,APBA2,GAS7,APP,CAMK2B,RUNX1T1,CACNA2D2,QKI,SIPA1L1,DZIP3,RASSF2,TBC1D5,EFNA3,PLXNC1,ACSL4,FHL1,SORBS1,TPK1,ALDH1L1,SRCAP,PRRC2B,HNMT,VWA5A,ADAM22,NF1,ODF2,CDK18,LRP12,MAPK8,MAPK10,PTN,PEX5,FBXW7,WLS,SH3BP2,PEX26,LIMCH1,KDM4B,EMC1,SPART,INKA2,SYN2,SEMA4A,TNS1,VIPR2,ZFP37,SPHK2,SLC30A3,WNK1,NUP214,TIGD6,SENP7" Drug 4133_DN "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,LTBP4,DOC2A,SEMA7A,APOC1,MARK4,ATM,CFLAR,BMP7,ASIC3,PLEKHB1,STOML1,DNAJB5,CPS1,CRMP1,DBN1,HP1BP3,EFNB3,ING4,EN2,ERCC2,ATP8A1,ZNF589,FGFR1,KHDRBS3,DISC1,RUNDC3A,GPER1,PCLO,IL11RA,KCND3,KCNQ3,GIT1,KCNK10,SERPINI1,PLXNB1,MAPK8,MAPK10,NKAIN1,RGS12,SEMA6D,FERMT1,LIMS2,TSNAXIP1,THSD1,ARC,EXOC7,TBCEL,TNS2,CABIN1,NSD2,NDRG4,UPF3A" Drug 1705_UP Dapsone [80-08-0]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "MRTFA,APP,NCOA1,SLC4A4,ARHGEF2,B4GALT6,CNTN1,CHD1L,ENTPD4,SOCS5,DBT,LYPD1,ATN1,EDNRA,HIPK3,PLEKHA1,DMTN,INPP5B,JAK2,NEK1,NF1,NFYA,CNOT4,NUMA1,CDK18,PLCD1,CNNM2,LRRC49,ARID4A,RGS10,GSTCD,WLS,CLIP1,PEX26,PPP4R3A,RAB3GAP1,BTBD7,SNCA,SON,TSNAXIP1,EMC1,CDK19,SPART,POGZ,PRRC2C,PLCB1,SYT1,WWC1,TBL1X,CHST8,CADM1,KCNAB1,UBE3B" Drug 3854_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADRA1D,DOC2A,CDC42BPA,GAS7,APOC1,CDK5R1,CA12,ARHGAP33,B4GALT6,BAG4,SH2B1,AKAP12,RIMS2,DMPK,EFNA3,FGFR3,ALDH1L1,SRCAP,GFER,PCDH17,POLL,MPP2,ADAM22,NF1,PLCD1,SLC25A23,LRP12,MBOAT7,SNRK,PTPRE,RIPOR1,ZSCAN2,ENOX1,TRIM68,RGS12,CLIP1,FAM214B,SHANK2,BTBD7,LIMCH1,SNCA,ZCCHC24,FNBP1,EMC1,TROVE2,COBL,KIAA1107,R3HDM1,TPM1,PLPPR2,LMF1,KCNK12,ZFP37" Drug 6312_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NME5,ALAD,CFLAR,ST3GAL5,MTMR3,CFAP410,ARHGEF1,SCARB1,CDH8,CACNA2D2,NRXN3,KIAA1549L,SULT4A1,AATK,PDE4DIP,DZIP3,CTIF,KIAA0753,RUSC2,LYPD1,ATN1,DUSP9,EFNB3,PLXNC1,COQ7,DMTN,EXTL1,ZNF589,FLT1,TRMO,GPR17,NR3C1,GRM1,GSTM5,HTR2A,KPNA5,LIG4,VWA5A,MDFI,PALM,LRP12,MAPK8,WDR25,PTH1R,RGS3,GSTCD,STUM,SH3BP2,CCDC88A,SMG6,DNAH7,SH3GLB2,NT5M" Drug 4806_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AP2A2,NME5,GAS7,PPFIA3,ARHGEF7,CACNA2D2,WHRN,CREM,ENTPD4,CRY2,SDC3,RIMS3,HP1BP3,SGSM2,SIDT2,COQ7,LRRC23,TPK1,GPR153,AHDC1,USP19,CACFD1,HSF2,KIF5C,LMO2,MITF,GIT1,NAP1L1,NOS1,NTRK2,PLXNB1,SAMD9,PLPPR1,PTHLH,RAD52,RGS12,ATXN2,SLC1A7,TSNAXIP1,ARHGAP26,SPTAN1,ZBTB43,TROVE2,ARHGEF9,KIAA0930,TRIM2,SZT2,AP4E1,SLC44A1,VAV2,NSD2,KCNAB1,SSPN" Drug 7539_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ARID1A,APBB1,MARCH3,ALDH4A1,NRP2,SCAPER,RCBTB2,SOCS6,CNOT8,HOMER3,CNIH3,MRNIP,PLEKHO1,EFEMP1,CELF1,OGA,USP19,DIPK1A,IPO5,LSS,MAPT,ADAM22,PLCD1,MED1,PTPRE,RAD52,BEND5,RFX2,ZNF331,FAM214B,SMARCD3,TMCC1,WDTC1,SP4,PBLD,ELOVL4,TTBK2,PLCB1,SYT1,ATP11A,EXOC7,CRTC1,AHCYL2,BHLHB9,TNS1,TPM2,FAM155A,LMF1,WIPF1,XRCC4,FIP1L1,EPM2A,PHTF2" Drug 6775_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "RALGAPA1,SLC12A5,KIAA1324,MRTFA,BIN1,KCNAB2,PRX,PDE8B,ASPH,N4BP2L1,SCAPER,CACNA1D,CBFA2T2,ARHGEF2,CLGN,QKI,SLC4A7,SIPA1L1,GREB1,DOCK4,CDON,HIPK3,EFNA3,MBNL2,STX2,RRAGB,ZNF589,FUT9,GPR19,SPACA9,GRIK5,GRM1,IL6R,JAK2,KIT,MN1,ZNF862,KCNK10,PDE1C,NLE1,PPARA,PKN2,RAD51D,TCP11L1,BTBD7,COA1,KIF13A,ZCCHC24,SPTAN1,ZEB1,TEX15,TMPO,PLPPR2" Drug 7219_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADCY6,AP1B1,FAM131A,MADD,ASPH,NUMB,CFLAR,PTBP2,KYAT1,KRIT1,CRLF1,TAOK2,QKI,HOMER3,CSNK1E,GREB1,GPRASP1,DCAF8,FBXL5,LYPD1,SGSM2,MED12,EDNRA,SIDT2,SUGP2,EGFR,MRNIP,STX2,ERBB2,FOXG1,DPYSL4,DISC1,COPS8,GLS,PRRC2B,BTN2A1,BRINP3,MAP4,PDE4A,CNNM2,RIPOR1,CEP97,RPS6KA2,SBF1,MAPKBP1,CLASP2,CAMTA2,KAZN,EXOC7,TBL1X,TCF7L2,ARHGEF12,MVB12B" Drug 3079_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,ALAD,ASPH,LDLRAD4,SOCS6,PLAA,CPS1,SEC31B,PDE4DIP,TM9SF4,SMG7,DTNA,MBNL2,TUBD1,COQ7,PIPOX,FECH,IQCG,FLT1,TRMO,ERAP1,GPD2,GSN,FICD,ACOT7,KPNA5,LAMA2,AFDN,ZNF862,NFYA,NRCAM,PDE4A,PKN2,MAPK8,PEX26,FAM214B,SLC6A8,SLC20A2,CDK19,ZC4H2,SS18,KANK1,CAMSAP2,DMXL2,AP4E1,KCTD2,HIRA,FLRT2,PLPPR2,XRCC4,SYNC,EMSY,KCNAB1" Drug 2298_UP Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "BEGAIN,APLP1,ATP6V0A1,CACNA1A,CALB2,RUNX1T1,MTMR7,CLCN4,TMEM59L,CSF1,SIPA1L1,VCAN,GREB1,RIMS2,JAKMIP2,SPOCK3,TMCC2,ERCC2,OLFM1,GLS,NXPH3,PTGDR2,ITIH2,KCNA2,KCNB1,KCND3,KHK,MID1,CD200,MSR1,OLR1,P2RX7,PDGFRA,PLCD1,EPN1,PDZRN4,PTPRN2,FAM120C,RYR1,SLC1A7,PKNOX2,SLC6A8,DOK5,SPTB,MAPK8IP3,SYP,WSCD1,TNS1,FAM155A,ZNF74,SLC30A3,ADAMTS9,JPH3" Drug 6818_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "SRPX,GAS7,BAIAP3,CFAP410,CACNA1A,USP2,CBFA2T2,CNTFR,NRG2,ATRNL1,PDE4DIP,RIPOR2,DCT,ELMO1,RUSC2,ATN1,SIDT2,MBNL2,ELAVL2,RAB30,GRIN1,RASSF8,HLF,ITIH2,ITPKB,KCNJ5,KCNK2,MAN2A2,AFF1,ADAM22,ZNF862,NEUROD1,NFIX,PRKCB,ZDHHC14,TRIM68,EMID1,RYR1,ZNF821,SH3BP2,ASAP3,FAM214B,SLC14A1,SNCA,WDTC1,CRTC1,CDK20,MICAL1,KCNK12,NT5M,DNALI1,ITM2C,JPH3" Drug 3822_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,GRAMD1B,KIDINS220,APAF1,APBB2,APC,CDK13,ADGRB2,NRP2,IL33,HAP1,CD86,FOXN3,NCOR2,ABCG1,CTH,MAML1,DTNB,EDIL3,EPHB1,ZNF391,GABRB3,MYOZ2,SRCAP,GFER,GLYR1,POLL,RAPGEF4,GRM2,SOX21,PADI2,KCNN2,ADAM11,NPTX2,NTRK3,PNMA3,PKN2,GDPD2,PTPRN2,RGS12,SH3BP2,KIF16B,SNAP25,SP4,HECW1,IQSEC2,ZBTB43,MAPK8IP3,MLC1,DOCK9,HIF3A,TPM3,FLRT2" Drug 5093_UP Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASIC1,ARID1A,APAF1,BRINP2,ALDH4A1,SCAPER,CA8,CHN2,DNAJB5,AKAP7,CRY2,PDE4DIP,ARHGEF4,TOM1,TENM1,DMTN,PTK2B,FGF1,SEMA4D,GAA,GLYR1,GPR75,SPACA9,SYNPO,ICA1,NPPA,PFKFB3,PKN2,MAPK7,SNRK,TMEM231,ZCWPW1,NEK11,RPS6KA2,SBF1,ZNF821,BTBD7,COA1,CAND2,ARHGAP26,DDN,MAPK8IP3,CEP68,SMG6,GPR161,NACC2,RUNDC3B,TRPC1,VAV2,CLIP2,LAT2,EVI5,EPM2A" Drug 5996_UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASIC2,SEMA7A,APBB2,GAS7,BACH1,RUNX1T1,CLGN,RAB33A,NRXN3,DNAJB5,QKI,NECTIN3,SLITRK5,RUSC2,DMPK,GNE,DUSP9,C3orf18,DMTN,STX2,FGFR1,GAB1,GPD1,NR3C1,GRM2,HAS2,KCND3,KCNMA1,KCNN2,VWA5A,MYH7,NNAT,NPTX1,PDE3B,NECAB2,ELOVL2,KLHDC8A,SEMA6D,RASA3,ASAP3,CNKSR2,PKNOX2,SMARCD3,DOP1A,ARHGAP26,THSD1,POPDC3,WSCD1,ZEB1,OBSL1,TEX15,R3HDM1,NUP214" Drug 2878_DN Iobenguane sulfate; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,PPFIA3,SEMA4G,BCL7A,SCAPER,ZFYVE9,ABI3BP,PHF14,LYPD1,DNM1,TOM1,EFNA3,EPB41L1,ZNF589,FHL1,DISC1,NR3C1,HSD17B1,TJAP1,MAP4,TM6SF1,GIT1,NEK1,NPR2,NTRK2,PDE4A,NLE1,PLCD1,PPP5C,MAPK7,PRPH,CNNM2,RIPOR1,ZSCAN2,CEP97,RALGDS,RGS10,NEK11,RYR1,SH3BP2,ABLIM3,CXXC4,RBM34,WDTC1,ZCCHC24,ATP11A,ZNF34,HEY2,UBE3A,MICAL1,DNALI1,NAV2,RNF170" Drug 4946_UP Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AP2A2,NME5,ALK,TRMT9B,APC,ASPH,RIPK1,CDK5R1,MTMR3,SGCE,CACNA1I,BAIAP3,CACNB2,NEURL1,CDH2,CLGN,KIAA1549L,CLCN4,ARHGEF6,TCEAL2,CSF1R,TBC1D5,DBT,DNAJC6,TMCC2,DNM1,DMPK,EDNRA,EGR3,TNK2,ATP8A1,GAD1,GPM6A,GPM6B,GRM7,BTN2A1,HLF,MGAT3,KCNK10,VPS13C,RGS12,MRAS,CCDC88A,TSNAXIP1,EMC1,IQSEC2,THRA,RIMBP2,TNS1,SEZ6L,FLRT2,LAT2,ZBTB14" Drug 2256_UP Etofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADGRB2,CACNA1I,BAIAP3,CACNG1,RUNX1T1,CHI3L2,CHN2,STOML1,CHD5,RIMS2,PPP6R2,EDRF1,TBC1D5,DGKG,SPOCK2,DRD1,DTNB,ZNF589,FGFR1,NSG1,GABRA5,ERAP1,ADAM28,GLS,GNAO1,HLF,SHISAL1,KCND3,MAP4,MBD1,NNAT,PDE4D,PIK3CD,TRHDE,PLPPR1,RAB3IL1,RPS6KA2,SYNDIG1,ASAP3,FNDC3A,SLC1A7,SLC2A5,SNAP25,FAIM2,SOX2,ZHX3,ACSBG1,TACR1,TLR4,TRPC1,BEST1,ZNF45,AP3B2" Drug 2550_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "APC,MARK4,SCAPER,CACNA1A,CBFA2T2,SOCS6,EPS15L1,TPP1,CREM,DCAF8,TM9SF4,KIAA0753,RHOBTB1,TRAPPC9,MRNIP,STX2,ST3GAL6,FECH,LILRA2,ATXN2L,KIF2A,VWA5A,MEF2C,MIA2,LRP12,PPP3CC,PTPRO,RAB3IL1,MAPK12,SEC14L1,SH3BP2,DZIP1,ANKRD6,KBTBD4,WDTC1,ZBTB43,TSPYL2,THSD1,FAM168A,TACC1,SLC44A1,TPM1,CDK20,SMUG1,ZMYND8,SSBP2,PLPPR2,LMF1,ZNF24,ZNF74,WNK1,EMSY,SMIM8" Drug 7362_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ARID1A,MRTFA,CDC42BPA,ARHGDIG,PDE8B,BMP7,LDLRAD4,CACNA2D2,FOXN3,TMEM59L,PICK1,WHRN,AATK,CNTNAP2,CYBB,DCT,AK5,CHRDL1,ATN1,ELAVL3,COQ7,ZNF549,FGFR1,AGAP2,FYB1,ZNF44,GLYR1,GNAL,GNG3,HLF,ICA1,LMO2,PACRG,MMP16,PPP2R2B,CNNM2,RAD52,RAP1GAP,ZCWPW1,ROM1,EMID1,SLC1A7,SNCA,ARHGAP26,DDN,KLHL4,SLC44A1,CABIN1,TRIO,VAV2,VIPR2,XRCC4,REEP1" Drug 6767_UP Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "DPF1,NDRG2,AGT,NME5,C1QTNF1,AMT,CDC14B,ASCL1,ALDH4A1,CFLAR,BAIAP3,CFAP410,ARHGEF1,STOML1,AKAP7,SNPH,DGKG,EFNB3,MBNL2,VPS13B,OLFM1,FGF13,FHL1,GPD1,LPAR4,GRB10,GUCY1B1,TJAP1,JAK2,KCND3,KCNJ5,MID1,AFDN,MMP16,MPP2,TAGLN3,ZNF862,NF1,CLDN11,PDE4A,NECAB2,MINDY2,ASAP3,SLN,TSPYL2,NPAS3,INKA2,MAPK8IP3,SYN2,AMACR,LAT2,KCNK12,SEMA3B" Drug 6472_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "AK2,PPFIA3,CDC14B,PLA2G4C,DNAH17,MARK4,LDLRAD4,MAGI1,CRLF1,B4GALT6,NECTIN3,ENTPD4,GREB1,PPP6R2,NOS1AP,TMCC2,TOM1,CNNM1,PLEKHO1,FGFR1,FAM49B,OGA,GLS,GNG4,FERMT2,TDRKH,STON1,CNTRL,GRB10,MGAT3,NELL2,NF1,P2RY1,PDE3B,PRPH,ELOVL2,RAB3A,FBXW7,WLS,SBF1,SMTN,DOK5,CLASP2,NXT2,MAPK8IP3,ARC,SEMA4A,CABIN1,ZMYND8,VGF,XRCC4,ACTR3B,SSPN" Drug 206_DN celecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASIC1,BRAP,ALAD,PPFIA1,ARNTL,HIP1R,TAOK2,VAX2,SULT4A1,PCYT1B,CPS1,C2CD2L,ARNT2,TRAPPC9,ATN1,RCAN1,EFNA3,KCTD3,ING4,SRPK3,FGFR1,SEC23B,GAB1,SLC2A6,NXPH3,ARHGAP19,KCNA1,IPO5,MITF,MMP16,MYO6,OPCML,PRKAR1B,RAB3A,BSDC1,ZC3H14,NTNG1,LIMS2,ZBTB43,PHLDB1,PLCB1,DDHD2,OBSL1,ATP13A2,CHST8,PARD3,SEZ6L,METTL3,VIPR2,SPHK2,GDPD5,NUP214,LAS1L" Drug 3357_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "OSBPL1A,APBB2,ATM,CFLAR,CDC27,SOCS6,NMT2,HOMER3,AKAP7,PDE4DIP,DZIP3,GIT2,MFAP3L,DSCAM,SEMA4D,FAM49B,ATP2C1,TRAF3IP2,USP19,MALT1,NR3C1,HNMT,HSF2,KHK,LSS,ZNF862,RETREG1,PLCD1,PRKAR1B,PRODH,TRAPPC13,SH3BGR,SH3BP2,ANKRD6,NUBPL,TMCC1,ZCCHC24,ZSWIM8,EMC1,SPTAN1,TSPYL2,TROVE2,SS18,ELOVL4,SEMA4A,MCF2L,FBXW11,RPGRIP1L,TK2,MICAL1,ZNF74,HPS4,C12orf4" Drug 2683_UP nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ABAT,CNTNAP1,ASPH,ATP2B2,ATP2B3,ATP6V0A1,SGCE,BRSK2,MAP7,CDC42,CDH10,CHGA,JAM2,CREM,RGS6,PDE4DIP,DMD,SEMA3D,MBNL2,SORBS3,OLIG2,FER,FLNC,SIGLEC8,GCNT2,GNAO1,GPM6B,LILRA2,GSN,KCNN1,KCNN3,LSAMP,MATN2,AFDN,NCAM1,PDE4D,PDGFRA,PPP2R2B,MAPK10,MASP1,CNNM2,PTPN13,RASGRF1,RGS4,RGS12,SUGCT,SALL1,SOX10,WSCD1,KCNE5,VAV2,VSNL1,NUP214" Drug 4017_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "APOC1,APP,SEMA4G,ATP2B3,ALDH7A1,SYNJ2,MYRF,KYAT1,CRLF1,CHI3L2,TAOK2,RAB26,PICK1,PDE4DIP,CTIF,DTNA,EDNRA,LRRC23,EZH1,ST3GAL6,AFF2,DLL3,GABRA2,GAD1,SYT17,GFER,ZNF276,POLL,ADAM22,GPR85,RETREG1,EPN1,GRAMD1C,RALGDS,DCUN1D2,FRMPD1,SLC1A7,SLC6A9,TSNAXIP1,CDK19,AHCYL2,GPR161,THRA,TK2,CABIN1,LILRA4,RPRM,MICAL1,XRCC4,NT5M,SCG2,SLC17A7,NUP214" Drug 4016_DN (-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "GRAMD1B,TRMT9B,APP,PDE8B,MARK4,ALDH4A1,ATP2B3,CACNA1I,MYRF,LDLRAD4,CACNB2,CRLF1,CHI3L2,LHX2,COL9A3,AATK,PDE4DIP,DZIP3,CTIF,PARD6A,ATN1,EFNA3,AASS,SORBS3,MTSS1L,FGF1,USP19,MSL3,POLL,GRM8,GUCY1A2,DHX35,ADAM22,MX1,NUCB1,PDE4D,MAPK7,RALGDS,ENOX1,KHDRBS2,KIRREL1,IL17RB,ZNF821,PKNOX2,SMARCD3,KDM4B,IQSEC2,ARC,SYN2,THRA,LILRA4,AMACR,KCNAB1" Drug 167_UP amitriptyline hydrochloride; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADCY2,BEGAIN,CDC42BPA,SEMA7A,APAF1,APBB2,BMP7,ST3GAL5,OSGIN2,CAMK2A,RUNX1T1,TBRG4,CHN2,CNTN1,CPS1,HS3ST2,DRP2,OPTN,SORBS3,VPS26C,BAIAP2,FHL1,NEU3,PCDH17,RUNDC3A,GPM6B,CNTRL,BTN2A1,KLF12,IL6ST,ITGAM,MBD1,NELL2,PMP22,PRKCB,PTPRD,RBBP6,RGS3,SEMA6D,PREX2,PKNOX2,SLC15A2,ZKSCAN3,SLN,ZHX3,SP2,ZC3H13,CDK19,CLSTN2,COLGALT2,ST5,RGL1,R3HDM1" Drug 284_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASIC1,NDRG2,KIAA1324,ALAD,CDC42BPA,AQP6,SEMA4G,PRX,CADM3,MYRF,LHX2,AATK,VCAN,CNTNAP2,APPL1,ARHGAP24,DAPK3,DBT,TUBD1,DMTN,CGREF1,GAD2,NCKAP1,MALT1,KCNMB4,GNAO1,GPM6B,IGF1,KCND3,KCNJ5,LAMA2,CTNNA3,MYL3,SETD4,RETREG2,RNH1,PAQR6,PREX2,KBTBD4,CDK5RAP2,KDM4B,NMNAT2,KLHL7,TCF7,THRA,TNS1,WNT7A,TFIP11,WNK1,STMN4,KCNAB1,NUP214,JMJD1C" Drug 5872_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "CDK10,PPP4R4,CADM3,CFLAR,CACNA1I,CDK5R2,CFAP410,CACNA2D1,MAP7,ARHGEF1,CDC42,RAB26,ARHGEF4,PYGO1,RABGAP1L,DSCAM,CELSR3,MBNL2,PLXNC1,NCALD,FGFR3,SCARA3,DISC1,GPR19,LPAR4,SPACA9,GRIN1,GRM7,NXPH3,KLF12,SCIN,KCNF1,KIF5A,MIA2,AFDN,NNAT,DUSP26,POLG,SAMD9,PTPRN2,KCTD17,TMEM206,FBXW7,SLC1A7,ARHGAP26,MCF2L,TAL1,UBTF,WIPF1,LAT2,ZNF74,WNK1,DPF3" Drug 6888_DN carmustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADD3,SLC12A5,SRPX,LTBP4,APC,PPP4R4,ATP2B1,MPDZ,BMP7,CDK5R1,CA12,CAMK2G,MAGI1,ADGRG1,FADS2,VAX2,SULT4A1,ABCG1,SIPA1L1,PDE4DIP,FAM169A,DZIP3,MFAP3L,PRKAG2,HBS1L,DISC1,GPR37,HSF2,TJAP1,INPP5B,MAN2A2,LYRM9,CNOT4,RGS10,RPS6KA2,KIF16B,ASAP3,ANKRD6,SHANK2,CXXC4,PDZRN3,ZCCHC24,CDK19,CEP68,VPS13A,KIAA0930,PSD3,HEY1,TMOD1,RPRM,ZNF24,GDPD5,HPS4" Drug 3000_DN Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "C3orf14,ACTN2,TRMT9B,APBB2,APP,CDK13,ATP2B2,AZGP1,NRP2,SLC16A4,SOCS6,CTIF,BRINP1,MBNL2,RASGRP2,MTSS1L,FGFR1,PDLIM5,GABRA4,SIGLEC8,SEPT9,LILRA2,GRK4,CACFD1,SLC2A6,MAP4,NUMA1,RALGDS,RGS10,TCP11L1,MAP6D1,CLIP1,MRAS,SH3BP2,SLC1A7,SNAP25,WDTC1,ZHX3,RAP1GAP2,MAPK8IP3,SYT11,CAMSAP2,KIAA1107,TCF7L2,PSD3,TPM1,TRO,SH3GLB2,KCNAB1,PCBP4,FAM13C,AAAS,JPH3" Drug 6307_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASPHD1,ADD2,PLA2G6,ADGRF5,APAF1,PPP4R4,CDK13,ZSCAN18,CFLAR,CACNA2D1,CAMK2B,ARHGEF1,SYNGR3,ARHGEF2,ARHGAP33,RCBTB2,PLEKHB1,CRMP1,AATK,RIMS2,ARMCX2,DTNA,EFNA3,CELSR3,EGFR,IRAK4,KIAA1109,FGFR1,FOXG1,ZNF276,GLS,GPR17,ADAMTS13,ICA1,VWA5A,KCTD15,POLG,RALGDS,RAVER2,SCN8A,ZNF821,ZFP30,BCAN,PEX26,CCDC88A,ZHX3,ATP10B,OBSL1,CRTC1,AP4E1,TK2,ZKSCAN5,RPRM" Drug 4157_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "PLA2G6,KCNAB2,ARSE,ADAM23,RGS9,CAMK2B,RUNX1T1,ADGRG1,AKAP7,WHRN,ELMO1,DMPK,HS3ST2,ST8SIA3,EDN3,MTSS1L,EPHB1,FGFR1,FOXG1,FAM49B,OGA,SIGLEC8,MYOZ2,ALDH1L1,POLL,GRM8,ATXN2L,HLF,ITGA7,KCNC1,KCNH2,MID1,SLCO1C1,NPTX2,NTRK2,KCNK10,GPR85,TNPO2,CNTLN,PNMA8A,PKNOX2,MYT1L,TNIK,BEX1,SPTB,MAPK8IP3,SYN2,TLR4,PRMT8,TRPC3,VAV2,EVI5,DPF3" Drug 2243_DN Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,KIDINS220,MARK4,BMP7,SYNJ2,GYG2,ARHGEF2,CDH10,CHRNB2,SLIT2,PICK1,RIMS2,CTIF,CDON,EIF4G2,EIF5,DISC1,GNG4,GRIK5,TJAP1,LSS,MAP4,ADAM22,NF1,NOS1,NPR2,CDK18,PIK3CD,MBOAT7,PRKAR1B,PRPH,PEX5,CEP97,C1orf54,ZDHHC14,RGS12,EMID1,SMARCD3,TSNAXIP1,IQSEC2,CLSTN2,PHLDB1,STX1A,PLCB1,ROBO3,TCF7L2,NSD1,AP4E1,VGF,ZNF24,SPHK2,KCNAB1,TIGD6" Drug 7374_UP Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "RALGAPA1,ARID1A,NDRG2,MTUS1,ALK,KCNAB2,GAS7,DDO,MADD,ADGRB2,C5,CACNA2D1,SLC16A4,ARHGAP33,ARHGEF10,CTNND2,BRINP1,DMPK,EFNA3,FAM13A,PLEKHO1,DENND4A,ETV1,CORO2B,FGFR1,BAIAP2,FYB1,GFER,KCNMB4,GPM6B,SPACA9,DIPK1A,KIF5C,MAPT,NF1,PIK3R1,PROX1,PTHLH,PTPRE,PTPRH,ENOX1,TRAPPC13,MRAS,DZIP1,SLC20A2,KDM4B,ACSBG1,GPR161,SEZ6L,ZKSCAN5,HIRA,SEMA3B,UBE3B" Drug 5242_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "PLA2G6,LTBP4,MRTFA,AMT,APC,PPFIA3,ALDH4A1,CFLAR,BTRC,CFAP410,CACNA1D,SYNGR3,CLGN,PLEKHB1,NMT2,CSNK1E,PARD6A,ATN1,EDNRA,HIPK3,SUGP2,EGFR,DMTN,FGF13,IQCG,PDLIM5,GLS,GNG3,HNMT,ICA1,KIF5C,LMO2,MIA2,ADAM22,PRODH,RGS10,RGS12,RPS6KA2,ABLIM3,SMTN,LIMCH1,THSD1,DIP2A,PHLDB1,PSD3,PCDHA5,ZNF34,TK2,PARD3,ZMYND8,PLPPR2,VLDLR,EPM2A" Drug 6312_DN Methiothepin maleate [19728-88-2]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "C1QTNF1,BIN1,AMT,CDC42BPA,APOC1,ALDH7A1,RAB29,NFS1,CNTNAP2,SDC3,PLPPR4,DNM2,SLC12A6,SIDT2,EN2,LRRC23,FER,EVL,TPK1,OGA,DISC1,INPP5K,TXNL4A,GLS,GNG4,GPR37,KCNMA1,FA2H,MINDY2,MAPK7,PRPH,PEX5,CCDC25,SAFB,ASAP3,FUZ,ANKRD6,SLC1A3,SMARCA4,WDTC1,NMNAT2,ARHGAP26,CDK19,ELOVL4,KANK1,ZNF34,TNS1,TRPC1,MICAL1,XRCC4,UPF3A,URM1,TIGD6" Drug 3140_DN Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ADD1,BIN1,ANK2,MARK4,CACNA1A,CAMK2G,CCNT1,JAM2,CNTN1,ENTPD4,CSF1,CSNK1E,ZNF337,SPOCK2,DBT,MAGI2,SMG7,DNM2,VPS13B,COQ7,NCALD,FECH,GAB1,SEPT9,GLYR1,LAMA2,GIT1,NCAM1,NINJ2,PDE4D,STRN3,MAPK7,CNNM2,PTAFR,MARCH1,RAB3IL1,BEND5,ZFHX4,TMEM206,ARFGAP1,TMCC1,KDM4B,SPTAN1,NCDN,ARHGEF9,KAZN,TCF7,PSD3,KCTD2,CABIN1,PLPPR2,XRCC4,ACTR3B" Drug 4484_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NME5,C1QTNF1,CDC42BPA,SEMA4G,CDK5R1,SCAPER,CAMK2G,SOCS6,ARMC8,WHRN,SNPH,EDIL3,CNNM1,SORBS3,STX2,ZNF589,FAM49B,SYT17,DISC1,GNG4,GPM6B,SCIN,KIF2A,MAPT,MEF2C,MEIS1,MIA2,NUMA1,PBX1,PIK3CD,MAPK8,PTN,ATG16L1,GSTCD,NEK11,ASAP3,BCAN,PEX26,SLC14A1,BTBD7,WDTC1,KDM4C,UNC5B,IQSEC2,JMJD6,SYT1,KAZN,ZEB1,CRTC1,TEX15,CABIN1,RPRM,SF1" Drug 5857_UP Isoconazole [27523-40-6]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "RALGAPA1,MTUS1,MRTFA,TRMT9B,ARRB2,ASPH,NRP2,MYRF,CFAP410,ASIC3,NRXN3,CSF1R,CSNK1E,PDE4DIP,ARHGEF4,EDN3,MBNL2,AASS,ELN,FCGRT,DCTN2,FYB1,DENND2A,ERAP1,TMEM8B,ELOVL5,TJAP1,SCIN,MAPT,MT1M,PPP2R2B,MAPK10,ZSCAN32,RAD52,MYH14,FBXW7,SBF1,FRMPD1,BCAN,ABLIM3,FAM214B,ELMO2,KDM4B,ARHGAP26,NCDN,PLCB1,ARC,DICER1,TK2,TNS1,WIPF1,LAT2,PARP6" Drug 4561_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ALK,AMPD3,APBB2,APC,MYRF,FADS2,HAPLN1,CSF1,TOX,SMG7,AK5,CHRDL1,EDIL3,MRNIP,SPEG,ETV1,SORBS1,CINP,SEPT9,SRCAP,USP19,GPR37,SHISAL1,TJAP1,SCIN,MAPT,MT1M,MYO7A,NASP,PALM,PBX1,PCDH9,PPP5C,PTHLH,SEC61A2,MYH14,ASAP3,SLC1A7,URGCP,ZHX3,UNC5B,DDN,THSD1,ST5,MAPK8IP3,PHLDB1,SYT11,CRTC1,RPRM,SPHK2,TFIP11,HPS4,SEMA3B" Drug 5876_UP Convolamine hydrochloride [500-56-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "RALGAPA1,ACTN2,PLA2G6,C1QTNF1,MRTFA,DOC2A,CACNA1I,BAIAP3,CA8,CACNA1A,MAP7,CDC42,ARHGAP33,JAM2,DNAJB5,PICK1,ARHGEF10,RIMS3,AK5,TRAPPC9,DUSP9,EDIL3,RGS17,HSD17B14,PIPOX,CORO2B,DLC1,GABRA5,TMEM8B,SEPT9,ADAM28,GPR22,GPR37,SCIN,KCNF1,KCNMA1,KCNQ3,KIF5C,SMAD1,MAPT,PDE4B,RAD52,ENOX1,SELL,DZIP1,FAM214B,ZHX3,ARHGAP26,ATP10B,ASTN2,REEP1,KCNAB1,DPF3" Drug 4838_DN Tocainide hydrochloride; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "ASIC1,ARID1A,ADRA1D,MRTFA,AMT,APBB2,FAM131A,APOC1,CDC14B,MARK4,ATM,SYNJ2,GYG2,PDE4DIP,MFAP3L,TSPAN5,EFNB3,MTSS1L,NCALD,DLC1,FGFR1,SCARA3,FAM49B,ERAP1,DISC1,GNG4,TDRKH,EML4,GRIK5,MAP4K5,HSF2,KCNH2,VWA5A,NF1,NFYA,PDE4B,PPARA,PPP2R2B,SAMD9,FAM120C,RAB3A,FNDC3A,SLC1A7,SOX2,UNC5B,ATP11A,TCF7L2,SLC44A1,THRA,TMOD1,VIPR2,WIPF1,TIGD6" Drug 380_UP tamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG3,BIN1,PDXK,ARSF,N4BP2L1,MTMR3,ARHGAP33,DLGAP1,CACNA2D2,NIPBL,ARHGEF4,C2CD2L,SMG7,SGK2,TNK2,MRNIP,OLIG2,PDLIM5,RASL10A,FYN,TRAF3IP2,BTN2A1,PTPRT,MAP4K5,NXPH3,L1CAM,MPP2,OMG,SNTG1,PALM,C11orf49,POLG,RAD51D,RNASEL,RYR3,SATB1,ZNF821,SH3BP2,FAM102A,SLC1A3,KBTBD4,GLT8D1,ZBTB43,LMO3,CLSTN2,GANAB,ACSBG1,TACR1,TBL1X,SZT2,SMUG1,CADM1,UBE3B" Drug 1734_UP Trolox [53188-07-1]; Up 200; 16uM; HL60; HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "MTUS1,PPFIA1,CNTNAP1,FAM131A,ADAM15,CAPN3,KRIT1,JAM2,CLCN3,FAM189A2,SMARCAL1,SH2B1,PPP6R2,RIMS3,C2CD2L,KLHL3,DLG3,TRAPPC9,DTNA,CDKL3,PIPOX,ANKMY1,OLFM1,DPYSL4,GAP43,ALDH1L1,RUNDC3A,GLS,ATXN2L,KCNN1,NEFH,OPA1,ZNF426,MBOAT7,MINDY2,CNNM2,GON4L,ZSCAN32,PTX3,ATXN1,ITSN1,AMBRA1,BTBD3,WDTC1,VAMP1,SZT2,SLC44A1,PLPPR2,REEP1,EVI5,GDPD5,HPS4,MPPE1" Drug 2139_UP Bicuculline (+) [485-49-4]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "BIN1,CASK,ARRB1,CADM3,ADGRB1,BMP7,BTRC,USP2,CABP1,CREM,CSNK1E,CNTNAP2,RUSC2,DLG3,EDIL3,EEF1A2,STX2,PDLIM5,CAMKK2,GPR153,FYB1,GALC,ALDH1L1,GCNT2,GPD1,ATF7,LILRA2,TJAP1,MAP4,ZNF862,KCNK10,PCDH9,MTRF1L,KLK6,PTAFR,PTPN13,RIPOR1,RAB3A,PID1,SBF1,STUM,FRMPD1,PKNOX2,SNCA,SOX10,CDK19,CEP68,CAMSAP2,TBCEL,SLC35G2,HIF3A,ATP13A2,RBFOX2" Drug 2744_UP Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "NDRG2,SEMA6A,ALCAM,APP,CALB1,HAP1,CDC42,CDH10,CHRNB2,LHX2,RAB33A,FADS2,ZNF804A,MAGI2,SGSM2,KBTBD11,EFNA3,TNK2,KCNMB2,FHL1,GPR153,TBR1,GLS,GPER1,KLF12,IL6R,KCNH2,KHK,LMO2,MATK,NF1,SMOX,MAPK8,RAD52,ZDHHC14,RGS12,EMID1,FBXO11,BCAN,FAM214B,SLC11A1,SHANK2,CXXC4,KDM4B,CLSTN2,KAZN,DOCK9,PSD3,ZKSCAN5,LAT2,PRDM2,KCNAB1,KAT6A" Drug 7295_DN Homochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "C1QTNF1,CDC42BPA,PPFIA3,BID,C5,CA12,ARHGEF1,ARHGEF2,CHN2,CLCN3,DZIP3,FAM131B,SGSM2,CDON,ATN1,FAM13A,SORBS3,EPHA5,TUBB4A,FGFR1,CAMSAP1,C1QL1,GLS,PRRC2B,GPER1,CNTRL,HNMT,MPP2,NFYA,OGG1,PTPA,GON4L,PTN,SH3TC2,RPS6KA2,SBF1,ITSN1,FAM102A,FHOD3,PEX26,BTBD7,SLC22A4,TNIK,BEX1,IQCE,OBSL1,TNS2,CBX5,ZKSCAN5,PLPPR2,SH3GLB2,URM1,PCBP4" Drug 3193_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.30E-05 1.00E+00 6.30E-04 7.17E-03 53 199 "SYN3,AMPD3,BIN1,AMT,ANK1,KCNAB2,GAS7,DDO,APP,ATP1A3,CACNB4,CAPN3,RUNX1T1,NEURL1,TAOK2,SLIT2,RAB33A,RGS6,VCAN,MBNL2,ELAVL4,MTSS1L,ACSL4,GATM,GNAO1,PTGDR2,AFDN,ADAM22,MYCN,TREM2,PENK,PLTP,PPP1R1A,PEX5,RASGRF1,CCDC102B,KCNIP1,LRRTM4,PPP1R9A,SH3GL2,ASAP3,CNKSR2,RPH3A,ARHGEF40,TSNAXIP1,CDK19,PLCB1,PCDHGA1,DICER1,TK2,TRPM2,SCG2,NUP214" Drug CID000042785 Lupex Stitch 5.44E-05 1.00E+00 6.45E-04 7.34E-03 37 124 "SERPINA3,ABAT,ACHE,ADCY2,ADCY5,ADCY6,ADCY8,AP1B1,CCK,CHGA,CHGB,CLU,ENO2,GAD1,GAD2,GFAP,NPY,OPRL1,PCSK1,PCSK2,PDCD2,PDYN,PENK,NLE1,CLIP1,DDN,SST,RGL1,SYP,SYT5,TAC1,TAC3,TRH,UCHL1,CLIP2,PORCN,SCG2" Drug DB00622 Nicardipine Drug Bank 5.46E-05 1.00E+00 6.48E-04 7.37E-03 9 14 "ADRA1D,ADRA1B,CACNA1D,CACNA2D1,CACNB2,CALM1,CHRM1,CHRM4,PDE1B" Drug 5223_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.48E-05 1.00E+00 6.51E-04 7.40E-03 49 180 "OSBPL1A,AMPD3,BIN1,ASPH,MPDZ,ST3GAL5,CHM,CLCN4,CLU,DNAJB5,ARMC8,CRY2,PDE4DIP,CTH,EDRF1,SPOCK2,ARMCX2,RCAN1,MBNL2,ING4,RUNDC3A,GRB10,NR3C1,ICA1,IL6R,IL6ST,MAP4,NAP1L2,NF1,MAPK8,KLK6,MORC4,TCP11L1,HSPA4L,SGK1,SH3BGR,ZCCHC24,HECW1,TSPYL2,POPDC3,TRIM2,BEX4,R3HDM1,RUNDC3B,ZMYND8,VLDLR,SEMA3B,NUP214,FXR1" Drug CID005288631 Im z Stitch 5.49E-05 1.00E+00 6.51E-04 7.41E-03 12 23 "BRAP,SEMA7A,CA4,TBPL1,ARHGAP32,ZMYND10,IGFBPL1,CNTN2,ZEB1,RGMB,SMUG1,RTN4" Drug CID000165791 lanthanum chloride hydrate Stitch 5.49E-05 1.00E+00 6.51E-04 7.41E-03 12 23 "ADRB2,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,RGN,ATP2C1,MAP4K5,P2RY1,MLC1,P2RY12" Drug CID000013538 beta-cyanoalanine Stitch 5.49E-05 1.00E+00 6.51E-04 7.41E-03 12 23 "NFS1,CBS,KYAT1,CTH,PCYOX1,GGT7,MATN3,YY1AP1,ASRGL1,CLSTN2,TK2,TST" Drug CID000000424 aspartate Stitch 5.56E-05 1.00E+00 6.59E-04 7.50E-03 115 518 "ABAT,ACLY,ABHD6,SLC25A25,BRAP,ADORA1,SEMA6A,SYT13,AMPD2,AMPD3,APAF1,APLP1,DDO,APP,ASPA,BCHE,WASF1,KYAT1,CCKBR,CDO1,CLCN3,CLCN4,CPS1,SLC32A1,GDA,CS,ACY3,B3GAT3,SLC25A18,ABI1,KCNMB2,GPHN,PTK2B,FER,FOLH1,GAD1,GAD2,MTHFD2,ALDH1L1,GFAP,GGT7,GGT5,GLRB,GLS,GLUL,GPT2,GPD1,GPD2,TUBA1C,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,ATE1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,PTPN5,GYG1,IDH3A,IDH3B,KCNJ3,KCNJ5,KCNK3,KIT,ASPRV1,MAPT,NTRK2,OGDH,OMG,PC,PCMT1,PFKP,PKM,PPP2R5C,PRODH,APTX,PSMD13,PTK2,RET,RNASE1,KCNIP3,ASRGL1,SHMT2,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC12A4,SNAP25,ADHFE1,SYT11,SYT1,SYT4,CYB561A3,CABIN1,NPL,TPM3,PDSS1,SLC13A3,ETNPPL,WNK1,STMN4,SLC17A7,SLC17A6" Drug 4542_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-05 1.00E+00 6.71E-04 7.63E-03 50 185 "DPF1,ACTN1,ADRA1D,MRTFA,APBB1,CDK10,PTCH2,CACNA1G,BAIAP3,BTRC,CACNA1D,SLC4A7,CPS1,AKAP12,CTH,CTNND2,EDN1,ING4,NRN1,FGFR1,AMOTL2,CINP,PDLIM5,FYB1,ERAP1,RND1,FERMT2,GPR19,SOX21,PTGDR2,KIF5C,SLCO1C1,SNTG1,PDE1C,PDE3B,PDE4D,NLE1,GRAMD1C,PRPH,SEMA6D,RASA3,SH3BP2,PDZD2,HECW1,PHLDB1,TBCEL,GPR161,R3HDM1,TRIO,ZNF24" Drug 2142_UP Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-05 1.00E+00 6.71E-04 7.63E-03 50 185 "ABHD6,ADORA3,ADGRF5,BIN1,DDO,APOC1,ASPH,ALDH4A1,PROM1,CACNB4,USP2,SLC16A4,SEPT7,NMT2,DNAJB5,PICK1,SIPA1L1,RIPOR2,PHC2,TNK2,KIAA1109,CAMKK2,TRAF3IP2,ADAM28,ZNF276,GLUL,GSN,ICA1,LYRM9,ZNF862,NRCAM,PLCL1,PRKCZ,PTAFR,ACSM5,MARCH1,RFX2,SYNDIG1,GALNT10,FNDC3A,SLA,SOX15,SAMSN1,KANK1,ASTN2,CAMSAP2,SLC13A3,SPHK2,ZBTB16,KCNAB1" Drug CID006857352 AC1OAGFW Stitch 5.67E-05 1.00E+00 6.71E-04 7.63E-03 50 185 "OSBPL1A,ANK1,MTMR3,MTMR2,CAST,MTMR7,CDC42,ZFYVE9,CLTC,CYBB,ARHGAP32,ZFYVE16,DNM2,PDCD6IP,EGFR,ABI2,PLEKHO1,GPHN,GRB10,RFFL,KCNA4,KCNN1,KCNN2,KCNN3,MAT2A,NCF2,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,EPN1,PBRM1,S100B,SBF1,HSPA4L,SGK1,RPH3A,NSFL1C,FGD4,ARHGEF9,PLCB1,MCF2L,TF,TIAM1,MTMR14,TSC1,SGK3,UBC,GORASP1,OSBP2" Drug 3103_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-05 1.00E+00 6.71E-04 7.63E-03 50 185 "ALK,BIN1,CDC42BPA,ANK3,PDE8B,DNAH17,CCDC181,INA,CD86,CD38,SLC22A6,RAB33A,ZFYVE9,ARMC8,ABI3BP,CREM,ABCG1,SIPA1L1,PDE4DIP,PPP1R16B,PHF14,DOCK4,KIAA0513,SPOCK2,CNIH3,ST8SIA3,SORBS3,BAIAP2,C1orf61,SORBS1,GNAL,RNFT2,HRH3,HNMT,MAP4,MEF2C,NPPA,PDE4B,PFKFB4,PID1,ROM1,SLC1A3,DOK5,ZSWIM8,IZUMO4,ZC3H13,TK2,RIMBP2,CLIP2,SLC30A3" Drug CID000446903 norbiotin Stitch 5.82E-05 1.00E+00 6.89E-04 7.84E-03 25 72 "ADORA1,CA4,NOG,CNR1,DRD1,EEF1A2,GAD1,GAD2,GFAP,GRIA1,GRIA4,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,NODAL,PKIA,TACR1,PORCN,SLC17A6" Drug ctd:D000641 Ammonia CTD 5.82E-05 1.00E+00 6.89E-04 7.84E-03 19 48 "AGT,AQP4,ATP1A2,ATP1A3,CLU,GATM,GFAP,GLS,GLUL,GRM1,GRM5,IGF1,MAP2,NOS1,NPR2,PDE4A,S100B,SLC6A8,SLC12A2" Drug CID006450460 avermectin Stitch 5.82E-05 1.00E+00 6.89E-04 7.84E-03 19 48 "GLRB,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,ABCB1,UEVLD,TAC1,TTPA" Drug 6697_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "ACTN1,MRTFA,PPFIA4,APAF1,APC,DDO,AQP4,ATP6V0A1,CANX,RUNX1T1,CBS,TAOK2,CLCN4,QKI,IFFO1,NCOR2,CSF1,MICAL2,VCAN,PDE4DIP,RIMS2,MFAP3L,SRGAP3,EDN1,MBNL2,TNK2,ZNF589,STMN2,MBP,ADAM22,DDX25,NNAT,OLR1,P2RY1,RETREG1,NLE1,LRRN3,PTAFR,PTX3,PKNOX2,SLC6A9,EMC1,CDK19,PDLIM2,RPGRIP1L,TJP1,CHST5,TRIO,UBE3A,ZNF24,NAV3" Drug 4421_DN Lidocaone hydrochloride [73-78-9]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "MRTFA,AMPD3,CNTNAP1,APC,ATM,ATP2A2,CFLAR,HAP1,CAMK2B,CACNA2D2,ADGRG1,SPOCK2,OPTN,HSD17B14,ERCC2,GPR153,OGA,GAB1,ALDH1L1,GCNT2,RUNDC3A,ICA1,IL6ST,ITIH2,MOBP,ADAM22,NEUROD1,CNOT4,PLPPR1,RAD52,ZNF821,FAM214B,PKNOX2,CCDC88A,SLC9A5,SLC11A1,KDM4B,PDZD2,IQSEC2,RBM26,ABCC8,ROBO3,TBL1X,TCF7,R3HDM1,TPM2,TRIO,ZMYND8,HIRA,VAV2,WNK1" Drug 3041_DN Luteolin [491-70-3]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "ADRB2,AMPD3,ANK2,NCOA1,SCAPER,CBR1,PLAA,CLCN4,ARMC8,SLITRK5,HDAC9,GIT2,RHOBTB1,RABGAP1L,KBTBD11,EXOG,NR1D2,DTNA,RBM12,LPAR6,VPS13B,SYNCRIP,IRF8,IFI16,KCNN2,MTR,NASP,PDCD2,GPR85,TRHDE,PTAFR,PTCH1,HSPA4L,ARHGEF40,FNBP1,CEP68,KANK1,GSE1,EXOC7,TCF4,ZEB1,THBS4,PARD3,TNS1,RBFOX2,SSBP2,UBTF,DNAJC12,XRCC4,PHTF2,ZNF248" Drug 3927_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "NME5,PLA2G6,LTBP4,APP,MTMR2,CFAP410,CBFA2T2,QKI,AKAP7,RCHY1,TBC1D5,MFAP3L,EXOG,HIPK3,FCF1,IRAK4,CAMSAP1,GALC,RAB30,GLS,ADAMTS13,JAK2,KCNJ3,MDM4,KITLG,AFF1,MPP2,NF1,NOS1,NUMA1,RETREG1,PTHLH,RGS10,ROM1,DOCK10,EPN2,KIF13A,KDM4B,SOX2,ZBTB43,THSD1,ST5,ARC,PCDHA6,HEY1,RUNDC3B,FAM155A,VIPR2,SYNC,EPM2A,AAAS" Drug 4314_UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "CNTNAP1,PPP4R4,ADAM15,BMP7,CAMK2B,NEURL1,ADGRG1,IFFO1,AKAP12,SV2B,ABCC9,EDN1,EDNRB,EFNB3,RGS17,ZNF549,FABP7,OLFM1,FGR,DPYSL4,GLYR1,GPM6B,IL6R,LAMA2,AFDN,MOBP,MT1M,NUMA1,CDK18,PFKFB4,MAPK7,RAB3IL1,RAD52,ENOX1,RFX2,MYH14,TMEM206,ASAP3,ABLIM3,SLC1A7,NCDN,KLHL4,TEX15,TRIO,TRO,PDIA2,VAV2,ZNF74,SLC30A3,NT5M,NAV2" Drug 3257_UP Apigenin [520-36-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "KIAA1324,BIN1,FUBP1,CACNA1I,BAIAP3,CFAP410,CBFA2T2,NEURL1,CDH2,QKI,CRY2,SRGAP3,EGR3,LRRC17,CDKL3,FAM198B,AMOTL2,TRAF3IP2,HBS1L,SESN1,C1QL1,RUNDC3A,GLS,GPER1,DIDO1,FICD,ITGA7,MAP4,ADAM22,ZNF862,PLCD1,SMIM7,PLTP,PPP5C,RET,DCUN1D2,RPS20,PAQR6,ZFP2,SCG5,PREX2,COA1,SNCA,DOK5,PEG10,ZBTB43,SYN2,ZMAT3,ZNF34,VIPR2,SEMA3B" Drug 2189_DN Acacetin [480-44-4]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "ADRB2,MTUS1,APP,ARRB1,NCOA1,RCBTB2,CLCN4,AKAP7,ARMC8,PDE4DIP,SLITRK5,CX3CR1,HDAC9,EFNA3,LPAR6,TNK2,EIF1,RASGRP2,SYNCRIP,POMT1,PDLIM5,INPP5K,SRCAP,DIDO1,SLC2A6,IRF8,IFI16,JAK2,VWA5A,AFF1,PLCB2,RC3H2,MINDY2,PPP3CB,SNRK,RET,LGR4,GALNT10,ARHGEF40,ZCCHC24,FNBP1,DBNDD2,RAP1GAP2,ZC4H2,CEP68,VAMP1,TCF4,SLC44A1,KAT6B,TPM1,MPPE1" Drug 3848_UP Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "SEMA6A,APOC1,ASPH,ADAM15,ADGRB1,CACNB2,ADGRG1,FADS2,CNTFR,IQCK,WHRN,NCOR2,SEC14L5,DAPK3,TMCC2,ATN1,SGK2,FCF1,ING4,KIAA1109,CAMSAP1,ANKFY1,KHDRBS3,GLYR1,GPER1,GSN,HLF,IL6ST,KCNH2,KCNK2,LSS,MID1,MYT1,NNAT,CLDN11,PAH,CDK18,CDK14,TNPO2,MASP1,RGS12,KCNIP1,SELL,ATP11A,TBCEL,PCDHGA1,UBE3A,FLRT2,ZIC3,NT5M,SENP7" Drug 7546_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "BRAP,SEMA4G,SLC4A4,MPDZ,BTRC,MAP7,CLU,NMT2,PICK1,AKAP7,WHRN,CREM,AKAP12,CRY2,ABCG1,CTH,KBTBD11,FEM1B,FAM13A,STX2,CDKL3,ETV1,FYB1,GSN,KLF12,INPP5B,ITPKA,LIG4,MMP16,PDE4D,SMOX,PRKAR1B,SAMD9,PTHLH,PTN,PTPRE,TRAPPC13,ASAP3,MYH15,ARHGAP26,SS18,SYT1,ASTN2,SEMA4A,SZT2,TIAM1,TFIP11,EMSY,HPS4,SEMA3B,PCBP4" Drug 914_UP rottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.83E-05 1.00E+00 6.89E-04 7.84E-03 51 190 "AP1B1,SPARCL1,CDC14B,RASL11B,CA4,ARHGEF2,LARGE1,CLGN,SLC4A7,BAG4,FEZ1,HP1BP3,ATN1,CELSR3,ING4,CDKL3,ST3GAL6,KIAA1109,SIGLEC8,RUNDC3A,GPD2,LPAR4,GRB10,PTGDR2,HTR5A,KPNA5,PACRG,MID1,MITF,NF1,PIK3CD,MAPK7,PRPH,FAM120C,C1orf54,RGS12,RPS6KA2,FNDC3A,NLGN1,ANKRD6,ZNF365,LIMCH1,UHRF1BP1L,TSPYL2,CAMTA2,THSD1,RUNDC3B,PLPPR2,VLDLR,WIPF1,NT5M" Drug 421_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "KIDINS220,ANK3,APOC1,WASF1,HIP1R,TAOK2,NIPBL,CRMP1,AATK,GPRASP1,JAKMIP2,DRP2,DSCAM,DNAJB6,E2F5,EGR3,ETV1,FGFR1,STAU2,STAG2,ZNF638,ADAMTS13,VSIG4,IL6ST,ITIH2,MBD1,MYO6,NAP1L1,NELL2,CCSER2,RETREG2,POLG,PPM1B,PKN2,GON4L,ARID4A,GSTCD,PAQR6,SFPQ,RAB3GAP1,KBTBD4,SLC20A2,TSPYL2,SS18,VAMP1,IQCE,AHCYL2,TK2,SEZ6L,TMPRSS5,VAV1,MPPE1" Drug 2897_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASPHD1,KIDINS220,FAM131A,CDC14B,ALDH4A1,SLC2A11,GYG2,CACNA1I,CALB1,CAMK2B,CAMK2G,NEURL1,FADS2,PICK1,CNTN1,CNTNAP2,GSDME,SUGP2,ELAVL3,PLEKHO1,ZMYND10,OLFM1,FOXG1,FLNC,TMEM8B,NEU3,SRCAP,ADAMTS13,FAM107A,SLC2A6,ITPKA,KIF5A,NUMA1,PC,PLTP,POU3F2,RGS12,RPS6KA2,KCNIP1,SCN2B,AMBRA1,KANSL3,CCDC88A,SLC9A5,BTBD7,NCDN,ACSBG1,ARC,TMEM121,LAT2,GDPD5,SSPN" Drug 3272_UP SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "C1QTNF1,LTBP4,APC,PPP4R4,ASPH,CFLAR,FOXN3,COL9A3,RCHY1,CRMP1,RIMS2,SMG7,PARD6A,ATN1,FAM49B,GAB1,GABRG2,RUNDC3A,GLYR1,BTN2A1,ICA1,KHK,SMAD1,MAOB,GIT1,BCO1,NOS1,NUMA1,PENK,SERPINE2,PLPPR1,PTHLH,ELOVL2,RAB3IL1,ZFHX4,RYR1,SLC2A5,LIMS2,PKNOX2,SLC11A1,COA1,ZNF423,ZC3H13,TSPYL2,TROVE2,POPDC3,TACR1,WSCD1,TCF4,SLC19A3,VLDLR,SPHK2" Drug 7323_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASPHD1,ABHD6,SLC12A5,PLA2G6,SRPX,BIN1,CDK13,PDE8B,ATP2A2,BCL7A,SCAPER,MTMR3,BTRC,CACNB2,CACNA2D2,HOMER3,MFAP3L,PARD6A,TRAPPC9,DSCAM,DUSP9,EIF4G2,EPHB1,FOXG1,HBS1L,SIGLEC8,SRCAP,POLL,PRUNE2,CNTRL,NR3C1,HAS2,HTR5A,MGAT3,MSI1,NF1,LRP12,KHDRBS2,SBF1,PREX2,SLC6A9,LIMCH1,PHLDB1,ARHGEF9,DICER1,AP4E1,ZNF34,HEY1,FAM155A,VAV2,WIPF1,SSPN" Drug 4771_UP Probenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ABHD6,ACTN2,ALK,BEGAIN,AMPD3,ASPH,SLC4A4,CADM3,BTRC,CACNG1,NEURL1,ARHGEF2,CDH10,RAB33A,HAPLN1,CRY2,FCF1,EFNA3,ZNF589,ALDH1L1,LYVE1,GPER1,IL11RA,ITIH2,MMP16,MPP2,MSR1,NF1,PLCD1,PURG,PRKCB,C1orf54,EMID1,RYR1,ZNF821,SLC1A7,PREX2,SLC2A5,PKNOX2,SLC8A1,SLC11A1,COA1,SNCA,DOK5,PEG10,OBSL1,CRTC1,TK2,TRIO,VIPR2,MICAL1,ST7" Drug 6147_UP Tropine [120-29-6]; Up 200; 28.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ALK,AMPH,BIN1,APBB2,CACNA1G,THSD7A,MAP7,RUNX1T1,CDH2,ARHGEF10,MICAL2,SIPA1L1,RIMS2,ARMCX2,SGSM2,EDN3,HIPK3,MBNL2,SORBS3,ING4,ERBB2,FER,C1orf61,AGAP2,PDLIM5,GAB1,ZMYND11,RUNDC3A,GSN,KIF5C,MAPT,MMP16,NINJ2,NTRK2,TREM2,PC,CCSER2,RASGRF1,CRTAC1,RFX2,KCNIP1,LIMS2,TMCC1,IZUMO4,KDM4C,ARHGAP26,TBCEL,WSCD1,TCF4,SEZ6L,SCG2,SLC17A7" Drug 3358_DN Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ADORA2A,LTBP4,ALK,APBB2,APLP1,BCAS1,CDK10,MARK4,NCOA1,CLGN,RCBTB2,FOXN3,LY86,CNTN1,WHRN,EDRF1,KBTBD11,DMTN,VPS26C,CINP,TPK1,SRCAP,FERMT2,GPR19,BTN2A1,RNFT2,DHX35,VWA5A,SMAD1,MID1,MMP16,PLCD1,PRKAR1B,GRAMD1C,LRRC49,ZSCAN32,RAB3A,RAD52,SLC6A8,RBM34,WDTC1,ZHX3,EMC1,ELOVL4,KAZN,TNS1,TRPC1,VIPR2,XRCC4,WNK1,KCNAB1,SSPN" Drug 1573_UP Fendiline hydrochloride [13636-18-5]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ARID1A,NDRG3,NDRG2,OSBPL1A,PLA2G6,BCL7A,CFLAR,BMP7,CAST,CHRNB2,PICK1,IQCK,LETMD1,SLC4A7,SEC31B,ENTPD4,SH2B1,C2CD2L,EXOG,SIDT2,TUBD1,ANKMY1,ATP2C1,OGA,TRAF3IP2,ALDH1L1,MALT1,HTATSF1,PRRC2B,NR3C1,ICA1,KCNN1,MBD1,NEFH,P2RX7,MINDY2,CNNM2,PTN,TRIM68,RNH1,RPS6KA2,SGK1,NTNG1,PPP4R3A,KBTBD4,ELMO2,WDTC1,ZHX3,UPF3A,LMAN2L,AAAS,DPF3" Drug 5112_DN Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "MTUS1,EIF4G3,ALDH7A1,ADGRB2,ARHGEF7,FUBP1,SCARB1,CLCN4,ARMC8,VCAN,CNTNAP2,SDC3,USP6NL,DNAJC6,SMG7,DYNC1I1,FCF1,CNNM1,ELAVL2,VPS26C,ZNF589,SEMA4D,TRMO,COPS8,POLL,MUM1,KLF12,AGFG1,IFI16,SCIN,INPP5B,JAK2,L1CAM,NF1,CNOT4,PBX1,PDE4A,STRN3,FSD1,MAPK7,BCAS3,SEC61A2,CCDC25,TRAPPC13,MAPK12,ZFP30,BEX1,HIRA,CADM1,WIPF1,XRCC4,ZNF225" Drug 7172_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "BRAP,AK2,CDK13,MAP7,CREM,CTNND2,PPP6R2,FEM1B,RBM12,TNK2,VPS26C,EFEMP1,FYN,GALC,RNFT2,MUM1,AGBL5,NEK1,CNOT4,PLEC,SLC25A23,RAB3IL1,RAB5B,RGS3,FBXW7,AMBRA1,URGCP,PDZRN3,KDM4B,SOX3,SPATA7,ZHX3,ZSWIM8,SS18,NCDN,CEP68,FAM168A,TACC1,SIN3B,SATB2,TCF7,ATP13A2,KCTD2,CABIN1,TP53BP1,SSBP2,ZKSCAN5,PLPPR2,VGF,LMF1,REEP1,MAP3K12" Drug 7540_DN semustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "RALGAPA1,ABR,ADCY6,ADD3,APP,CDK10,ARHGDIG,MARK4,ST3GAL5,CA12,UBE2L6,QKI,COL9A2,PDE4DIP,DZIP3,DBT,FBXL5,ATN1,EIF5,EPB41L2,EFEMP1,SRCAP,IRAK3,NFYA,NUMA1,PDE3B,MTRF1L,PKIA,PRODH,PRPH,SNRK,MYH14,LGR4,WLS,MAPK12,SH3BP2,EPN2,SLC20A2,SLC22A4,RBM34,KDM4B,CLSTN2,INKA2,PLCB1,IQCE,BHLHB9,R3HDM1,KAT6B,CADM1,RPRM,VAV2,KAT6A" Drug 6259_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "BIN1,AMT,APC,CDC14B,BCL7A,CFLAR,GYG2,LDLRAD4,ZMYM4,QKI,CREM,LRIG1,EFNB3,SUGP2,MBNL2,VPS13B,EPB41L1,LRRC23,FGFR1,BAIAP2,FOXG1,IQCG,GAB1,GPR19,BTN2A1,HNMT,TM6SF1,ADAM22,NEUROD1,NF1,PDE3B,CDK14,RETREG1,LRP12,MAPK7,SAMD9,WDR25,BSDC1,RGS4,FBXW7,PPP4R3A,PDZD2,KIF21B,FNBP1,UNC5B,NPAS3,CLASP2,PSD3,CABIN1,TNR,VIPR2,KCNAB1" Drug 5980_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "NME5,AK2,BIN1,PDE8B,CACNA1I,LDLRAD4,CD86,CDC42,ARHGAP33,CBARP,TAOK2,NRXN3,NRG2,CSNK1E,CNTNAP2,DSCAM,DTNA,SEMA3D,PLEKHO1,RABEPK,NCALD,DLC1,KIAA1109,BAIAP2,ERAP1,SIGLEC8,DISC1,GRM1,HSF2,IGFBP1,KCND3,KIF2A,MSI1,PDGFRA,PFKFB2,RETREG1,PLPPR1,RGS4,RGS10,GSTCD,PPP4R3A,IZUMO4,SPTAN1,SYT1,MCF2L,GPR161,VGF,ZNF711,PARP6,NAV3,SLC17A7,DPF3" Drug 6739_DN Hemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "APOC1,PDE8B,MARK4,ALDH7A1,ADAM23,CACNA1I,DNAJB5,WHRN,MFAP3L,SPOCK3,ST8SIA3,SUGP2,AASS,SORBS3,MRNIP,MTSS1L,FYB1,DENND2A,TMEM8B,LYVE1,LPAR4,ICA1,MAPT,MEIS1,NEUROD1,NF1,SNTG1,PRKAR1B,MAPK7,GRAMD1C,PTN,ZSCAN32,RIPOR1,BSDC1,RGS10,KIRREL1,FBXW7,FOXRED2,WDTC1,TSNAXIP1,SPTAN1,RBM26,LHPP,THSD1,PHLDB1,RPGRIP1L,DOCK9,PCDHA5,TRIO,WIPF1,MAP3K12,HPS4" Drug 5241_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ABAT,ASIC1,AK2,FAM131A,RGS20,BRINP2,NCOA1,CACNA1I,CFAP410,CRLF1,LHX2,NRG2,CREM,CSNK1E,EDRF1,EGFR,EZH1,FGFR1,SEPT9,SRCAP,GFER,GNG4,GPD2,GPM6B,TDRKH,RASSF8,ATXN2L,AGBL5,IL6R,KCNF1,MID1,MITF,NPR2,MBOAT7,FSD1,MAPK7,IL17RB,SH3BP2,PPP1R9A,FAM214B,SNCA,DOP1A,WDTC1,EMC1,DBNDD2,CDK19,TROVE2,PSD3,AP4E1,TIAM1,MICAL1,SENP7" Drug 6071_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ALK,BEGAIN,PLA2G4C,DDX3Y,RGS9,CACNA1I,RUNX1T1,CDO1,LY86,CNN3,CSF1,CHD5,CNTNAP2,NOS1AP,SPOCK2,DCT,SGK2,EFNB3,OLIG2,TUBB4A,GPR153,GABRA2,SRCAP,GFAP,GNAO1,STON1,GRIK1,AP4S1,GUCY1A2,KCNMA1,KIFC3,KIT,MEF2C,AFDN,TAGLN3,MX1,PCBP3,NTRK3,PLXNB1,PMP2,MAPK8,SAMD9,RFX2,KLHDC8A,TCP11L1,PPP1R9A,ASAP3,SLC11A1,KIF21B,TLR4,TRIO,UBE3A" Drug 3862_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "PLA2G6,KCNAB2,APOC1,SEMA4G,ALDH4A1,ADAM15,CACNA1I,USP2,SLC16A4,ADGRG1,TPP1,FADS2,SULT4A1,CNTFR,AKAP6,SNCAIP,CSF1R,CNTNAP2,FAM169A,SNPH,DAPK3,ING4,ERCC2,CAMSAP1,CAMKK2,GLYR1,HTATSF1,GPER1,GSN,IL6ST,LSS,TM6SF1,KITLG,ADAM22,SLCO1C1,PKN2,PTHLH,FAM120C,GAL3ST4,SEMA6D,CPEB3,ST6GAL1,ZBTB43,NCDN,ARC,TBCEL,SLC44A1,TRIO,VAV2,SLC13A3,NLRP3,RNF146" Drug 2396_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ABAT,NDRG2,ADGRF5,PPFIA1,APAF1,PPFIA3,ARRB2,ASPH,ZSCAN18,MTMR3,CDH2,CHM,CPNE6,CLCN4,HOMER3,PICK1,SLC4A7,ENTPD4,CRMP1,CTH,DCAF4,GSDME,SV2A,DLC1,AFF2,EFCAB2,ZNF44,SEPT9,INPP5K,POLL,ICA1,ITIH2,KCNJ5,LAMA2,CLDN11,LRRN3,MAPK8,MAPK10,KCNIP1,SEC14L1,SLC11A1,SNAP25,IQSEC2,TROVE2,KAZN,TCF7L2,FAM189A1,TK2,SSBP2,LAT2,KCNAB1,PHTF2" Drug 7540_UP semustine; Up 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ADORA3,AMH,BIN1,KCNAB2,ALDH4A1,CFLAR,BMP7,MTMR3,SGCE,ZMYM4,CDH18,MAGI1,CLGN,STOML1,VAX2,IQCK,CREM,CSNK1E,SDC3,KIAA0513,RIMS3,CTIF,GIT2,C3orf18,EN2,FECH,AFF2,SORBS1,GPR153,DISC1,USP19,CRCP,BTN2A1,KCNQ3,LSS,ZNF862,RETREG1,PPP3CC,MAPK8,RAB3IL1,CCDC40,CARF,SLC15A2,EXOC7,DMXL2,SZT2,TK2,ICAM5,TRIO,LMF1,ZNF45,MVB12B" Drug 3335_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "NME5,PLA2G6,BEGAIN,SEMA4G,ATP6V0A1,CACNA1I,CFAP410,CACNA2D1,INA,ARHGEF2,ADGRG1,CHM,SLIT2,SLC4A7,DGKG,SPOCK2,CDON,CNNM1,EFNB3,MBNL2,RASGRP2,ABCA8,ZNF589,KIAA1109,PDLIM5,GAB1,GAD1,GFER,RND1,GLYR1,GNAS,GRM1,GSN,KCNJ3,MAOB,AFF1,MYT1,NNAT,PCBP3,CLDN11,KCNK10,PDE3B,CDK14,EPN1,PDZRN4,ZNF493,ZDHHC14,ASAP3,SZT2,VAV2,WIPF1,SLC17A7" Drug 402_UP rapamycin; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "NDRG2,ADCYAP1R1,PLA2G6,BCAS1,AQP6,PDXK,SLC4A4,ATP2B2,N4BP2L1,THSD7A,HAP1,CD86,DLGAP2,CHGA,LHX2,PCYT1B,SOCS5,CYBB,DAPK1,DCC,EFNB3,LPAR6,LRRC23,KCNMB2,EYA1,FGF12,C1orf61,CYP46A1,RUNDC3A,GUCY1A1,HLF,HAPLN2,KCNJ10,MYL3,NAP1L1,GPR173,CDK14,RETREG1,PPP5C,GAL3ST4,RNH1,ROM1,LIMS2,SHANK2,SNCA,NMNAT2,LMO3,TRPM2,UCHL1,VIPR2,PMEPA1,KCNAB1" Drug 6183_UP trifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "MTUS1,ALK,TRMT9B,BIN1,CNTNAP1,PDE8B,PTCH2,ATP2B2,SYNJ1,CACNA1I,MYRF,BTRC,CHRNA4,CSF1,ARHGEF10,RIMS2,EDRF1,SNPH,DAPK3,DBT,ATN1,DYRK1A,MBNL2,MRNIP,RASGRP2,ANKMY1,F5,FAM198B,FGF1,CAP2,GPR153,B4GALNT1,PCLO,CD200,NFIX,NTRK3,PDYN,CCSER2,RETREG1,PLCL1,FSD1,CEP41,FBXW7,SLC1A7,RIMS1,SCN3B,TNIK,ARHGEF9,SYN2,TRH,ZIC3,PRDM10" Drug 7362_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "PPFIA3,APP,MARCH3,NCOA1,ALDH4A1,MPDZ,ARHGEF1,HOMER3,AKAP7,ARMC8,KIAA0513,TMCC2,DLG3,HSD17B14,F3,ZNF589,ATP2C1,DISC1,COPS8,GLRB,GLS,DIPK1A,MITF,MSRA,PAK3,RGS10,UEVLD,ZNF671,TCP11L1,LGR4,DOCK10,FNDC3A,SLC1A3,SHANK2,SLC22A4,LIMCH1,SS18,ELOVL4,SYNE2,VAMP1,ARHGEF9,SYT1,KIAA0930,SYNE1,TK2,TRPC1,UBE3A,ZBTB14,SMIM8,PHTF2,ADAMTSL3,RNF170" Drug 4322_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "DPF1,SLC12A5,LTBP4,PPFIA4,CDK10,CDK13,FUBP1,CBS,RCBTB2,ARHGAP22,CLTB,CNTN1,WHRN,CSNK1E,INTS1,MAML1,CTIF,C2CD2L,SPOCK3,SGSM2,DTNA,ABCA8,TRAF3IP2,ADAM28,GPM6B,GPER1,GRIK5,SYNPO,ICA1,KCNMA1,PBX1,CDK18,PFKFB4,MAPKAP1,TNPO2,RGS4,TMEM206,FBXW7,SEMA6D,ASAP3,ST6GAL1,ANKRD6,SMARCA4,KDM4B,IQSEC2,PHLDB1,ARHGEF9,SZT2,GPR161,LAT2,WNK1,MVB12B" Drug 7254_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ALAD,AMPD3,APC,APOC1,SLC4A4,CFLAR,RUNX1T1,SOCS6,LHX2,NRXN3,DZIP3,SNPH,DBT,MFAP3L,SMG7,CELSR3,EGFR,RGS17,PLEKHO1,BAIAP2,GRM1,SCIN,IL11RA,DIPK1A,ADAM22,NEK1,NUMA1,MBOAT7,MAPK7,FAM120C,ATG16L1,MRAS,SLC20A2,LIMCH1,TSNAXIP1,ZHX3,EMC1,KDM4C,ZBTB43,SS18,DIP2A,SYT1,ADGRL3,WWC1,TNS1,PIK3R5,SSBP2,VIPR2,WIPF1,NT5M,NAV3,KCNAB1" Drug 5590_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "PLA2G6,C1QTNF3,APBA2,APBB2,EPB41L5,FAM131A,MARK4,NCOA1,ALDH4A1,ATP6V0A1,CFLAR,GYG2,KRIT1,NMT2,FADS2,DZIP3,GPRASP1,EFNA3,FGFR3,GPR153,GHR,MALT1,RAB30,MSL3,GPR19,CNTRL,CACFD1,BTN2A1,HNMT,MATK,KITLG,NF1,RETREG1,SLC25A23,PRKAR1B,WDR25,RALGDS,ZDHHC14,RBM34,ZHX3,SPTAN1,CLASP2,EXOC7,TBCEL,TPM1,CDK20,PLPPR2,VAV2,NDRG4,HPS4,MPPE1,ACTR3B" Drug 4223_UP Nystatine [1400-61-9]; Up 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "AMPD3,PPFIA4,APC,ASCL1,ADGRB2,KSR1,BMP7,CAMK2B,CCK,CBFA2T2,TMEM257,ARHGAP33,PLEKHB1,CABP1,CNTNAP2,CTNND2,SRGAP3,ARNT2,EDN1,EDN3,HEYL,AASS,SRPK3,MTSS1L,AGAP2,SIGLEC8,GPD1,AP4S1,HPSE2,KCND3,ADAM11,MSI1,ADAM22,NEUROD1,NPTX1,GPR88,PPARA,LRRN3,SUSD4,SLC6A15,PBRM1,SLC4A3,SLC6A11,SLC8A1,IZUMO4,IQSEC2,RBM26,CABIN1,LILRA4,VAV2,WNK1,SLC17A7" Drug 3923_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "AP2A2,LTBP4,AMPD3,APLP1,PLA2G4C,MARK4,BRINP2,ATM,SLC2A11,ATP6V0A1,RIPK1,ARHGEF1,CBFA2T2,FOXN3,SOCS6,B4GALT6,TAOK2,ZFYVE9,RCHY1,SDC3,EDRF1,MAML1,DBN1,DCTN1,LYPD1,ATN1,DTNA,C1orf61,KHDRBS3,GALC,SRCAP,GLYR1,GLS,ADAMTS13,KCNN1,ADAM22,ZNF862,NUCB1,PCDHGC3,PLCD1,SLC25A23,SMIM7,NKAIN1,MSANTD2,ZNF821,ARHGAP26,ZBTB43,TROVE2,PARD3,TRIO,ZKSCAN5,PLPPR2" Drug 7359_UP Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASPHD1,AMH,APAF1,APBB2,CDK10,CDK13,MTMR3,CCNT1,AP4M1,QKI,HOMER3,SIPA1L1,TBC1D5,C2CD2L,RABGAP1L,DSCAM,OPTN,SRPK3,DLC1,ST3GAL6,KIAA1109,FAM49B,SRCAP,GNAS,GPR19,SPACA9,GRM8,ATXN2L,ELOVL5,JAK2,KIF5C,ADAM22,NDUFA5,NF1,NOS1,PRODH,TMEM104,RGS12,FBXW7,SLC6A9,SLC22A4,LIMCH1,ZCCHC24,MAPK8IP3,TTBK2,PLCB1,WSCD1,SLC44A1,TMOD1,DNAJC12,MICAL1,ST7" Drug 3547_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "CNTNAP1,EPB41L5,DDO,ATP1A3,BCL7A,CFAP410,CA4,SLIT2,FAM149A,MYRIP,CHD5,VCAN,PDE4DIP,EFNA3,EGFR,OLFM1,KHDRBS3,GAP43,DISC1,GNAS,CNTRL,GRM8,IL6ST,KCNA2,KCNC1,MGAT3,NF1,NPTX1,NTRK2,OPCML,PIK3CD,PMP2,PPARA,GDPD2,PTPRB,CRTAC1,KCTD17,RPS6KA2,ASIC4,BCAN,PKNOX2,COA1,SNCA,WDTC1,SPTAN1,TBCEL,GPR161,TNS1,SLC30A3,KCNAB1,MVB12B,AP3B2" Drug 2149_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "BEGAIN,BIN1,ADGRB1,FUBP1,CACNA2D1,DNAJB5,RAB26,COL9A2,DAPK1,RUSC2,SGSM2,DTNA,ABCC9,FAM13A,EIF1,FGFR1,FGFR3,CAMSAP1,FHL1,CGREF1,GPR153,GAP43,INPP5K,ZNF276,GRM2,PADI2,MAN1B1,KLF12,IL6ST,MAP4,TAGLN3,ZNF862,EPN1,MED1,CEP41,ZCWPW1,ZFHX4,NEK11,RPS20,FAM102A,SLCO1A2,SNCA,NPAS3,CEP68,CAMSAP2,TBL1X,SLC35G2,RBFOX2,ZMYND8,RPRM,SYNC,SLC17A7" Drug 6510_DN Scopoletin [92-61-5]; Down 200; 20.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASPHD1,APLP1,CFLAR,BMP7,PLAA,LRIG1,SIPA1L1,FAM169A,SDC3,DCAF8,DAPK3,C2CD2L,LYPD1,SMG7,RABGAP1L,RBM12,EGFR,KAT8,FGFR1,BAIAP2,GPR153,INPP5K,GNG4,GOLGB1,STON1,GRIK5,IL6R,MAP4,MEIS1,NF1,OGG1,MINDY2,FAM120C,RIPOR1,CEP97,RAD52,RGS12,RNASEL,AMBRA1,PEX26,FAM214B,PKNOX2,SLC20A2,LIMCH1,KANK1,TACC1,WDR7,TRPC1,ZNF24,EMSY,MVB12B,ST7" Drug 3082_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "RALGAPA1,ABAT,AMPH,ANK3,PLA2G4C,ARSE,CACNB4,CBFA2T2,CLGN,FAM149A,SH2B1,ABCG1,RUSC2,SV2A,DLG4,ST8SIA3,CALCRL,RCAN2,DLL3,GPR75,GNAL,GPM6B,PCLO,GUCY1A2,ATXN2L,ICA1,KCNJ5,KCNQ3,KHK,MAP4,MX1,NOVA1,OMG,CLDN11,PFKFB4,LRRN3,PRKAR1B,CNNM2,BCAS3,SYTL2,RFX2,ZFHX4,SYNDIG1,FAM102A,KDM4C,ARHGAP26,SPART,TROVE2,AJAP1,DAAM2,CLIP2,NUP214" Drug 1701_UP Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASPHD1,KIDINS220,AK2,APOC1,ARNTL,CFAP410,CACNA1D,SOCS6,RAB28,FADS2,QKI,CSF1,ARHGEF4,EDRF1,TBC1D5,JAKMIP2,NR1D2,RCAN1,HIPK3,MBNL2,RRAGB,PRKAG2,CGREF1,POLL,HMGCR,ICA1,INPP5B,KCNJ3,MAP4,MBD1,MEIS2,NF1,PMP22,CEP41,PRKAR1B,MAPK8,LRRC49,WDR25,RAB3IL1,RAD51D,RAD52,PKNOX2,BTBD7,SLN,TTBK2,TRIM2,SZT2,ZKSCAN5,REEP1,GDPD5,GAN,SENP7" Drug 2313_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ADRA1D,AP2A2,BIN1,SEMA7A,APOC1,CDK13,SLC2A11,ALDH7A1,CA4,RCBTB2,ASIC3,RAB33A,SLC4A7,CSF1,PDE4DIP,SDC3,LYPD1,CELSR3,DMTN,FOXG1,SEPT9,INPP5K,MSL3,GRM1,ICA1,TJAP1,KCNN1,VWA5A,MAP4,MIA2,NF1,PCDH9,PDE3B,PLCD1,STRN3,LRP12,MBOAT7,ELOVL2,CEP97,RAD52,ATG16L1,TRIM68,TCP11L1,EMID1,WLS,BTBD7,EMC1,TROVE2,AP4E1,PLPPR2,ZIC3,MAP3K12" Drug 2520_DN Tetrandrine [518-34-3]; Down 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.99E-05 1.00E+00 7.01E-04 7.97E-03 52 195 "ASIC1,NDRG2,ADRB2,TRMT9B,AMPD3,BIN1,AMT,APBB2,KIF1A,CDH10,SIPA1L1,CTIF,SPOCK3,ABI2,SORBS3,RASGRP2,MTSS1L,FGFR1,EFCAB2,GABRA2,SEPT9,ARFIP1,GNG3,LPAR4,GRM8,MAP4,MAPT,MYT1,NUMA1,ST8SIA5,FAM120C,ZCWPW1,FOXRED2,MRAS,FRMPD1,BTBD7,SNCA,WWC1,DMXL2,ZEB1,TNS2,THRA,TMOD1,KCTD2,TNS1,TRIO,FLRT2,XRCC4,SH3GLB2,PRDM2,FAM13C,ACTR3B" Drug CID000001297 4-carboxy-3-hydroxyphenylglycine Stitch 5.99E-05 1.00E+00 7.01E-04 7.98E-03 11 20 "ALDH7A1,GRIK1,GRIK3,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID003021728 CI-930 Stitch 5.99E-05 1.00E+00 7.01E-04 7.98E-03 11 20 "ALDH7A1,KRIT1,ATP8A2,CIT,PDE1C,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PDE1B" Drug CID000003688 IDRA 21 Stitch 5.99E-05 1.00E+00 7.01E-04 7.98E-03 11 20 "CFLAR,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3" Drug CID000037783 PDBu Stitch 6.01E-05 1.00E+00 7.03E-04 8.00E-03 63 249 "ADCY5,ADCY6,ADCY8,ADORA1,ADRA1B,SLC24A4,AGT,APLP1,DGKZ,DGKD,APP,ARHGDIA,ALDH7A1,CACNA1B,CACNA1E,CACNA2D1,CALM1,CAMK2B,CAMK2D,DGKI,LRBA,CHRM1,CLCN3,MYL6B,DGKB,DGKG,EDN1,EDN3,EDNRA,RASGRP1,CELSR3,RASGRP2,FGF1,GAP43,RAPGEF1,HTR2A,MYLK2,KCNJ5,MBP,KITLG,MYL3,NRGN,PKM,FXYD1,MBOAT7,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,PSMA6,RTKN,SST,PLCB1,TAC1,TRH,ANKS1B,MFF,RGMA,PLD4" Drug ctd:D012601 Scopolamine Hydrobromide CTD 6.01E-05 1.00E+00 7.03E-04 8.00E-03 36 120 "ACHE,ADORA3,AGT,APP,MADD,CACNA1D,CHRM1,CHRM4,CHRNA4,CHRNB2,ABCG1,EGFR,EML1,CAMKK2,GABBR1,TNRC6A,HRH3,KCNA4,KCNB1,KCND2,KCNJ3,MAPT,NOVA1,NOVA2,NTRK2,NTRK3,PDYN,PENK,ABCB1,ARC,SYP,TAC1,ROBO3,VGF,SLC47A2,RGS7BP" Drug 1681_DN Epirizole [18694-40-1]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "BRAP,KIDINS220,PKP4,CASK,ASPH,ATP2A2,ATP6V0A1,SYNJ2,OSGIN2,CACNA1D,PTBP2,COL4A5,SLC4A7,CREM,LRIG1,RUBCN,DBN1,DNAJC6,PARD6A,GNE,FEM1B,SIDT2,SUGP2,DENND4A,KAT8,FGFR1,TRMO,CSPG5,FERMT2,GPR19,SLC2A6,MPP2,PBX1,SIDT1,GON4L,RIPOR1,TMEM231,ZCWPW1,FBXW7,ZC3H14,ZSWIM8,KDM4C,CAMTA2,ITPRID2,NCDN,TBL1X,CLASP1,WBP2,METTL3,HIRA,ZNF184,SEMA3B,RNF170" Drug 2134_DN Sparteine (-) [90-39-1]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ARNTL,SLC4A4,CAPN3,USP2,ARHGAP33,ZFYVE9,PLAA,TPP1,CSF1,SIPA1L1,VCAN,DZIP3,DGKG,CTIF,SMG7,SV2A,ING4,PCOLCE2,ELN,RASGRP2,CDKL3,AFF2,KHDRBS3,ZNF44,SRCAP,DIDO1,FICD,ELOVL5,MYT1,NPR2,NRGN,PLTP,PILRA,RAD52,ZDHHC14,MYH14,ZNF821,EPN2,SLC11A1,ZKSCAN3,MAPKBP1,KDM4B,WDTC1,IZUMO4,ATP11A,PDLIM2,SZT2,RBFOX2,TPM1,PLPPR2,VIPR2,LAT2,XRCC4" Drug 6029_UP Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "AGT,C1QTNF1,SEMA6A,BIN1,CDC42BPA,RASL11B,CACNA2D1,CAMK2B,RUNX1T1,CD86,SLC24A2,WHRN,MYRIP,SNCAIP,ERC2,NOS1AP,RIMS3,ELMO1,DYRK1A,HSD17B14,CAMKK2,FYN,GABRA4,PCDH17,RUNDC3A,ADAMTS13,GRM2,GUCY1A2,ATXN2L,KLF12,IL11RA,CD200,CDK18,PFKFB2,ZNF493,RGS12,EMID1,RASA3,SLC8A1,KDM4B,SPP1,MLC1,ATP11A,TBCEL,CRTC1,CRB1,HEY2,TNS1,SEZ6L,VLDLR,LAT2,NT5M,NLRP3" Drug 6034_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "KCNAB2,APOC1,BCAS1,ATP6V0A1,ADAM15,CACNA1I,BTRC,CA4,USP2,ARHGEF2,SLIT2,CNTFR,RCHY1,SMARCAL1,FEZ1,GREB1,GIT2,PARD6A,DLC1,FHL1,DPYSL4,HBS1L,MALT1,GLYR1,GPD2,NR3C1,KCNJ3,KCNN2,IPO5,MAP4,MMP16,MPP2,ADAM22,PDE3B,PMP22,PPP5C,PEX5,RGS12,ZFHX4,GSTCD,TCP11L1,PPP1R9A,ASAP3,ANKRD6,PHLDB1,AJAP1,VAMP1,PLCB1,ANKRD12,EXOC7,PCDHA6,TK2,KCNAB1" Drug 369_DN rosiglitazone maleate; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "PPFIA1,AQP6,ATP1A2,AZGP1,P2RX6,JAM2,TAOK2,TJP2,TMEM184B,CNTN1,ECE2,GIT2,KLHL3,PARD6A,SORBS3,F5,TBR1,GLS,TDRKH,RNFT2,PADI2,ICA1,KCNA1,MAP4,MARK3,NNAT,NPR2,NTRK3,PDCD2,PHKG1,PKIA,PRKAR1B,MASP1,SPDL1,RIPOR1,RAP1GAP,RGS3,PCMTD2,SATB1,DOCK10,KBTBD4,PHLDB1,KAZN,TBL1X,TCF4,BHLHB9,RBFOX2,SEZ6L,TMPRSS5,NSD2,ZNF142,LMAN2L,MPPE1" Drug 1952_DN "Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; PC3; HG-U133A" Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "BRAP,MRTFA,PPFIA3,ATP2B1,CDC27,ZFYVE9,NIPBL,CREM,SOCS5,FAM169A,RUBCN,KIAA0586,SPATA2,DMTF1,MAMLD1,TSPAN5,EFNB3,ELAVL2,C3orf18,ATP2C1,AHCYL1,SEPT9,GLS,GRIK5,NR3C1,GSTM5,IL6ST,KTN1,MARK3,SCAMP5,MYO6,NAP1L1,NFE2L2,SERPINE2,RC3H2,MBOAT7,MED1,RALGDS,RFX5,SLC11A1,SON,STXBP1,POPDC3,ANKRD12,TBL1X,TCF4,WDR7,RBFOX2,ZMYND8,ZNF184,EVI5,MPPE1,PDSS2" Drug 6617_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "DPF1,KIDINS220,ANK2,KCNAB2,BCAS1,N4BP2L1,ATP6V0A1,ADGRB1,BMP7,CACNG1,CAMK2B,CHRNB2,CNTFR,IFFO1,RIMS3,DGKB,DTNA,EDNRA,HIPK3,AGAP2,ERAP1,TMEM8B,ATP8A2,GRIK2,ITIH2,KCNC1,KIT,LIFR,MMP16,ADAM22,NEFM,NOVA1,PDE3B,PFKFB4,PPARA,PPP5C,ZSCAN2,ROM1,TCP11L1,ASAP3,SLC2A5,PEX26,HECW1,PHLDB1,COBL,TACR1,TNS1,SMUG1,TRIO,ZNF24,PARP6,KCNAB1,EPM2A" Drug 2719_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "KDM5D,ADCY2,ADORA1,BEGAIN,LGR5,ZSCAN18,ALDH4A1,MYRF,CDO1,CHN2,ZFYVE9,TCEAL2,SPOCK2,DBT,DMPK,EDIL3,EFNA3,ELAVL3,ANKMY1,ARMCX1,DLC1,ATP8A1,FLT1,PRELID3A,NSG1,RUNDC3A,HTR2A,ICA1,DIPK1A,MGAT3,MMP17,NEFM,NPPA,CLDN11,OXTR,TMOD2,PLCD1,PNMA3,FSD1,BCAS3,PTPN13,PBRM1,SYNDIG1,FAM214B,TNIK,TACR1,TCF4,TF,CHST8,ZKSCAN5,UBE3A,BEST1,ZBTB38" Drug 5831_DN Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ADRA1D,AK2,PPFIA1,APBB2,CASK,CFLAR,SCAPER,NIPBL,WHRN,SLC4A7,CSNK1E,VCAN,SLITRK5,ZFYVE16,SPOCK2,DBT,EPB41L1,ERBB2,DENND4A,BAIAP2,SCARA3,FYN,GAD1,ERAP1,INPP5K,GCNT2,GSN,DHX35,NF1,PLCD1,LRP12,POLG,MAPK7,RGS4,SEC61A2,PAQR6,TMEM156,ATXN7,COA1,TNIK,UNC5B,TSPYL2,ARHGEF9,COBL,ARHGEF12,ZMAT3,TPM4,METTL3,TRPM2,UBTF,LMF1,ZNF189,UPF3A" Drug 5538_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ABHD6,AP2A2,EP400,SCAPER,OSGIN2,MAP7,VAX2,NIPBL,CTNND2,DCAF8,ZNF337,GIT2,KIAA0753,SMG7,SUGP2,EIF5,DCTN4,PLEKHO1,COQ7,USP21,GART,SRCAP,AHDC1,EML4,RNFT2,KCNF1,KCNJ3,KIF5C,MSI1,ADAM22,OPA1,PRKAR1B,ZCWPW1,ARID4A,RGS3,ARHGEF10L,FBXW7,PREX2,SMARCA4,MAPKBP1,ATP11A,FAM208A,ARHGEF12,SLC44A1,CABIN1,PIK3R5,VAV1,VGF,XRCC4,ZBTB14,PRDM2,MPPE1,GAN" Drug 2348_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "NDRG2,MRTFA,CNTNAP1,PDXK,ARRB1,NCOA1,CFLAR,CACNG1,SEPT7,SULT4A1,ENTPD4,FEZ1,USP6NL,SEC14L5,DTNA,COQ7,DLC1,FCGRT,C1orf61,ANKFY1,PDLIM5,INPP5K,LILRA2,NR3C1,SOX21,SLC2A6,PADI2,ITIH2,VWA5A,MAP4,NELL2,NPR2,NUMA1,CCSER2,PMP22,LRRN3,GAL3ST4,RGS10,TCP11L1,NLGN1,SLC9A5,SNCA,DOK5,KIF1B,SYT11,PDLIM2,WSCD1,TCF4,TMOD1,ZKSCAN5,UBE3A,LAT2,ADAMTS9" Drug 4440_UP LY 294002; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ABAT,ADRA1D,AQP4,ARSE,PDE8B,ALDH4A1,SLC2A11,N4BP2L1,ST3GAL5,GYG2,CALB2,CAMK2A,HIP1R,RUNX1T1,CDO1,CHI3L2,TAOK2,VAX2,CNIH3,CHRDL1,CDON,TENM1,ELAVL3,SORBS1,FYB1,GATM,GPR75,GNAO1,GRIA4,KCNF1,KCNH2,LSS,MYO7A,NEUROD1,NPTX1,RETREG1,PPP1R1A,PTN,PTPRN2,CARF,FOXRED2,DOCK10,LIMS2,PKNOX2,SLC11A1,NCDN,MCF2L,PCDHGA10,OBSL1,CDK20,ZIC3,SLC17A6,MVB12B" Drug 3565_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "SYN3,ADD2,MRTFA,KCNAB2,SEMA4G,CADM3,SYNJ2,GYG2,BAIAP3,CFAP410,CALB2,CBLN1,SLC22A6,COL9A3,CHD5,VCAN,ATN1,EDNRB,EGFR,MBNL2,C3orf18,HSD17B14,EPHB1,STX2,SPEG,ETV1,GAB1,GABRA5,GAD1,TMEM8B,RND1,GNAO1,GPM6B,HLF,IL11RA,KCND3,SMAD1,MAOB,MEF2C,BCO1,NCAM1,NTRK3,OPRL1,PRKAR1B,RELN,RGS12,SLCO1A2,SLN,SOX2,ATP10B,NTSR2,TUBB1,VAV2" Drug 995_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "KIDINS220,AK2,MRTFA,NCOA1,ATP6V0A1,CACNA1D,SRSF11,B4GALT6,RAB28,HOMER3,AKAP7,AKAP12,NCOR1,DBT,DMPK,ING4,SCML2,FGFR3,SYT17,MALT1,HTATSF1,KCNMB4,FERMT2,ARHGAP19,KCNJ3,IPO5,MAP4,MBD1,MMP16,NAP1L2,NASP,PCDH9,PDE3B,PLEC,LRP12,RETREG2,RXRA,MAPK12,SGK1,EPN2,SMTN,SHANK2,SLC20A2,NCDN,NSFL1C,ASTN2,WWC1,IQCE,PCDHA6,LMF1,SF1,ZBTB14,PHTF2" Drug 3432_DN Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "AP2A2,EPB41L5,CAPRIN2,EIF4G3,CRLF1,LHX2,QKI,NCOR1,DCAF8,GIT2,SMG7,STX2,F3,SEPT9,GSN,HSD17B1,IL6ST,INPP5B,KIF5C,ADAM22,ZNF862,NASP,PDE4A,SMOX,PRPH,ELOVL2,ZCWPW1,ARHGEF10L,ROM1,FBXW7,FAM192A,SBF1,ITSN1,FERMT1,ABLIM3,PPP4R3A,SMARCA4,SMARCC2,WDTC1,SPTAN1,ANKRD12,ATP13A2,CABIN1,LMF1,SF1,ZBTB14,NDRG4,ZNF189,PMEPA1,MAP3K12,HPS4,SEMA3B,WIPF2" Drug 2664_DN "aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ABAT,NDRG2,KIDINS220,TRMT9B,PPFIA4,CACNA1G,CACNA1A,PLAA,CX3CR1,CTIF,SPATA2,TRAPPC9,EIF4G2,ELN,ERBB2,FHL1,FYB1,ZNF44,RUNDC3A,POLL,GRM8,ATXN2L,TJAP1,KCND3,LSS,MAP4,MAPT,AFDN,MYO6,NUMA1,OLR1,PDE4A,PLTP,PMP22,SYTL2,RAB3IL1,FOXRED2,SCN2B,RASA3,FRMPD1,NLGN1,BTBD7,SNCA,SOX2,ARHGAP26,CAMSAP2,TCF7,TNS2,VIPR2,LMF1,CLIP2,XRCC4,TIGD6" Drug 4170_UP Myricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "SEMA6A,APBA2,MARK4,ATP2B2,MTMR3,CACNA1I,CALB2,CBARP,CHRNA4,CHRNB2,LHX2,AKAP7,CNTNAP2,DMPK,CDON,EDN1,FHL1,DCTN2,DISC1,GFER,RUNDC3A,HPGDS,GPR19,GPR22,GRM7,KHK,MATK,MEF2C,NEUROD2,NPY,NTRK2,NECAB2,PPP2R2B,MARCH1,RGS12,RNASE1,PNMA8A,SCN8A,STUM,KANSL3,SLC11A1,SMARCA4,PDZD2,ATP10B,INKA2,JMJD6,TEX15,ZIC3,SLC30A3,WNK1,NT5M,CAMK1G,ADAMTSL3" Drug 4841_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "LTBP4,CDK10,CAPRIN2,MAP7,KRIT1,SCARB1,SRSF11,MAP4K4,HOMER3,AKAP7,COL9A2,LRIG1,FAM169A,MFAP3L,MED12,DTNA,FEM1B,SUGP2,GPR153,GART,HNMT,HSD17B1,IGSF1,IPO5,MAN2A2,NUCB1,OGG1,PDE3B,RETREG1,PLEC,PMS2,RALGDS,RGS12,MAPK12,ZNF821,FERMT1,FUZ,AMBRA1,ZNF365,ZKSCAN3,SMARCA4,CDK5RAP2,TMCC1,ZBTB43,ARHGEF9,ASTN2,EXOC7,TBL1X,MTMR14,NSD2,HPS4,KAT6A,SSPN" Drug 5603_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "NDRG2,GAS7,PDE8B,SYNJ1,CAMK2B,SOCS6,CRY2,CTIF,MFAP3L,MAGI2,SMG7,TOM1,TNK2,HSD17B14,DLC1,FGFR1,FOXG1,FAM49B,TPK1,GPR153,GAP43,ALDH1L1,ADAM28,TXNL4A,GRB10,ADAMTS13,GSTM5,HLF,MEF2C,KCNK10,PC,PDE3B,PLPPR1,FAM120C,FOXRED2,ZNF821,SH3BP2,FAM214B,ZCCHC24,ZHX3,RBM26,PHLDB1,VAMP1,TBCEL,CRTC1,TGFBR3,SLC44A1,TNS1,TRPC1,PLPPR2,VAV2,REEP1,MAP3K12" Drug 5879_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "KIDINS220,ALK,APC,ADAM23,IL33,CAPN3,MAP7,CBFA2T2,SCARB1,CDH8,CLCN4,QKI,SULT4A1,COL9A3,VCAN,RIMS3,GIT2,TOM1,RGS17,SYT17,KCNMB4,TDRKH,PTPRT,SCIN,KCNQ3,ADAM22,NPTX1,PRKAR1B,ZSCAN32,RIPOR1,TMEM231,ACSS3,FAT4,BEND5,MYH14,FBXW7,TCP11L1,SELL,DZIP1,ANKRD6,ARHGEF40,SLN,TNIK,ARHGAP26,SAMSN1,SEMA4A,TRIM2,PCDHGA10,BEX4,NT5M,STMN4,ADAMTSL3,NLRP3" Drug 2409_UP Bumetanide [28395-03-1]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ANK3,APC,APP,PRX,CADM3,BMP7,CACNA1A,REPS2,HOMER3,CREM,DGKG,CTIF,DSCAM,FCF1,MBNL2,MTSS1L,CDKL3,FOXG1,SORBS1,TRAF3IP2,SEPT9,INPP5K,GLS,GRIK2,GRM1,ATXN2L,ICA1,TAGLN3,NINJ2,SERPINE2,CAMKV,LRP12,MINDY2,MAPK8,PTPRD,KCTD17,KLHL11,ASAP3,DOCK10,SNAP25,ZCCHC24,RAP1GAP2,SS18,MAPK8IP3,CRTC1,TEX15,TGFBR3,ZNF34,TMOD1,TNS1,TUBB1,VGF,FAM13C" Drug 3991_DN Carbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "APBB2,APP,LGR5,CDK10,ALDH7A1,ARHGEF1,TAOK2,LHX2,WHRN,SH2B1,CRMP1,AATK,TENM4,SLITRK5,CTIF,CNIH3,ATN1,DTNA,EFNA3,EGFR,PLXNC1,SPEG,ST3GAL6,ANKFY1,AFF2,TRMO,GPR19,ICA1,LMO2,MAPT,GIT1,OPCML,PC,EPN1,PTPRB,PID1,RAD52,ZCWPW1,RGS10,RXRA,FRMPD1,FAM214B,SLC22A4,ZNF667,MAPK8IP3,ARC,TK2,RIMBP2,CABIN1,TRIO,RPRM,EVI5,SCG2" Drug 3997_DN Cefotetan [69712-56-7]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "PPFIA1,APC,APP,DNAH17,NRP2,KIAA1549L,SH2B1,CRMP1,PARD6A,TRAPPC9,ATN1,EIF5,ST3GAL6,AFF2,GFER,GPER1,GUCY1B1,KIF2A,MAP4,CNOT4,NOVA1,OPCML,PDE1C,PDE4D,PLCD1,EPN1,PTPRB,RAB3IL1,FAM184A,ZCWPW1,ENOX1,ARHGEF10L,MYH14,KIRREL1,FBXW7,FRMPD1,FNDC3A,EPN2,SLC6A9,ARHGAP26,ZBTB43,MAPK8IP3,ADGRL3,TK2,RPRM,OSBP2,PLPPR2,WIPF1,XRCC4,MAP3K12,KCNAB1,NUP214,TIGD6" Drug 7015_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ACLY,NDRG3,AP1B1,CDC42BPA,MADD,NUMB,ZMYM4,SOCS6,CLCN3,QKI,CREM,MICAL2,CTH,GIT2,DNAJC6,KIAA0753,RABGAP1L,DSCAM,MAMLD1,FEM1B,SUGP2,VPS26C,EFEMP1,USP21,ATP2C1,CSPG5,TRAF3IP2,GRB10,RNFT2,MAP4,AFF1,NUCB1,OPA1,FSD1,PRKACB,ZSCAN32,SAFB,SUPT20H,KIF16B,SIRT2,SCMH1,ARFGAP1,CDK5RAP2,IFT122,MAPKBP1,TROVE2,CAMTA2,NCDN,FAM208A,ARHGEF12,TRIO,UBTF,ZNF189" Drug 6141_UP Meropenem [96036-03-2]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "SERPINA3,ACTN2,DOC2A,AMPH,BIN1,CDC42BPA,APBB2,PRX,ATP1A3,ATP2B2,RGS11,MTMR3,BTRC,FHL5,CNR1,PLCH2,KLHL3,HS3ST2,DYRK1A,EDN1,SORBS3,ELAVL4,ATP8A1,KAT8,FOXG1,KHDRBS3,GCNT2,GLRB,HNMT,TJAP1,SCAMP5,MMP16,NEUROD1,NPPA,NTRK3,PSD,PLPPR1,RERGL,MYH14,SH3GL3,CNKSR2,PKNOX2,PDZRN3,MYO16,TNIK,CAND2,DDN,SSTR2,PHLDB1,CRTC1,TJP1,STMN4,SLC17A7" Drug 4740_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ADORA1,SYT13,BEGAIN,TRMT9B,AMPD3,GAS7,SEMA4G,RGS20,PDE8B,DNAH17,ATP2B2,RGS9,PROM1,SCAPER,BAIAP3,CDH8,DNAJB5,AATK,ARHGEF10,RIMS3,MFAP3L,C2CD2L,CDON,ATN1,ELAVL3,EN2,RASGRP2,MTSS1L,FGFR1,GABRA2,GAD1,GFAP,CSDC2,GNAL,GPD1,PCLO,GRM7,IGF1,KHK,MAPT,ADAM11,MSR1,EPN1,MTRF1L,CCDC40,CCDC88A,AMACR,TRPM2,SLC13A3,SLC30A3,DNALI1,KCNAB1,ITM2C" Drug 2481_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ACTN2,ADORA1,APBB2,SEMA4G,PDE8B,KIF1A,KSR1,BMP7,CACNA1I,CA12,CLCN4,COL9A3,ABI3BP,NCOR2,SIPA1L1,DCAF4,RIPOR2,MFAP3L,CDON,OPTN,ERBB2,OLFM1,FGFR1,GAD2,PCSK1N,GRM2,GRM8,KCNJ5,KCNQ3,KHK,MEF2C,MMP17,NAP1L2,NEFM,PDE4D,PMP22,STRN3,RC3H2,MAPK7,RGS4,KCTD17,TCP11L1,EMID1,SYNDIG1,NTNG1,ZNF365,SHANK2,SSTR2,MAPK8IP3,PHLDB1,CRTC1,ATP13A2,FAM155A" Drug 2477_UP Etifenin [63245-28-3]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ADORA1,C1QTNF1,SYT13,MRTFA,CDC14B,ARSE,PDE8B,PTCH2,BMP7,CACNA1I,CFAP410,SLC16A4,LARGE1,CDO1,ZFYVE9,PICK1,CREM,DCAF4,BRINP1,CHRDL1,CDON,ATP8A1,FER,FGFR1,AGAP2,AFF2,GAA,GAP43,GLRB,ADAMTS13,KCNQ3,KIT,MAP4,MEF2C,NAP1L2,NOS1,NPPA,CCSER2,EPN1,PPP2R2B,LRRN3,SYTL2,RGS12,TCP11L1,SYNDIG1,PKNOX2,TSPYL2,MAPK8IP3,PHLDB1,TBCEL,KCTD2,SEZ6L,SSPN" Drug 4475_DN Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "NME5,SEMA4G,CASK,ARNTL,CDK13,MARCH3,ASPH,MTMR9,CDK5R1,SYNJ2,IL33,KRIT1,CBFA2T2,RCBTB2,SOCS6,CHN2,NMT2,ABI3BP,CNTNAP2,SDC3,DCAF8,TOX,KIAA0513,DLG3,RCAN1,EIF5,MRNIP,STX2,ETV1,CINP,B4GALNT1,GPM6B,GPER1,HNMT,INPP5B,MMP16,PCDH9,PFKFB2,PAQR6,IL17RB,KDM4D,DOP1A,SPATA7,NXT2,MAPK8IP3,DICER1,BHLHB9,TMPO,CADM1,MICAL1,WNK1,PRDM2,PHTF2" Drug 3741_UP Karakoline [39089-30-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ADCY2,FAM135A,BEGAIN,ARSE,ZSCAN18,RASL11B,N4BP2L1,HAP1,TAOK2,EDRF1,TOX,SPOCK3,EDN1,MBNL2,DCTN2,TBR1,GAP43,GATM,CNTRL,ICA1,C2orf72,TJAP1,KIFC3,MATN3,NDUFA5,NTRK2,CLDN11,KCNK10,PDE2A,PRODH,RGS4,RGS12,MYH14,CARF,CPEB3,SOX2,SOX10,KDM4C,ATP10B,LARP4,FAM168A,ACSBG1,ARC,ADGRL3,ZEB1,RPGRIP1L,SLC44A1,BHLHB9,TNS1,CDK20,LAT2,STMN4,NUP214" Drug 7170_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ASPHD1,PPFIA3,CDC14B,PLA2G4C,PDE8B,ALDH7A1,ADAM23,BCL7A,MAGI1,CHM,TMEM59L,QKI,AKAP7,ARMC8,BAG4,HAPLN1,PDE4DIP,GIT2,JAKMIP2,LYPD1,DSCAM,EFNA3,COQ7,F3,FHL1,GPR153,TXNL4A,GLS,KCNMB4,HNMT,LIG4,MEIS2,ADAM22,NF1,NOVA2,SAMD9,PTPRH,FAM120C,NKAIN1,RGS12,KCTD17,DCUN1D2,GSTCD,PPP4R3A,CLASP2,WSCD1,TRIO,ZMYND8,ZNF74,REEP1,NAV2,MPPE1,SMIM8" Drug 4091_UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "GAS7,ATP1A2,RGS11,CA8,SYNGR3,NEURL1,CHI3L2,TAOK2,TPP1,PCYT1B,RIMS3,SPOCK2,SPOCK3,EDNRB,SRPK3,OLIG2,PIPOX,AGAP2,GFRA1,GNAL,SPACA9,GRM8,GSTM5,GUCY1A2,KCND3,KCNF1,MAG,DDX25,NCAM1,NDUFA5,NEUROD1,PBX1,PENK,DUSP26,PLXNB1,PPP1R1A,CCDC40,RFX2,PNMA8A,SEMA6D,SCN2B,ST8SIA1,KANSL3,SLC6A9,ARHGAP26,SPART,TACR1,SLC19A3,OBSL1,DAAM2,SEZ6L,BEST1,KCNAB1" Drug 4618_DN Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "APP,MADD,PDE8B,STX16,CFLAR,ARHGEF7,LDLRAD4,BTRC,CFAP410,SPAG9,MAP7,PLEKHB1,ABCG2,BAG4,CNTNAP2,DZIP3,ARHGAP32,RCAN1,CELSR3,MBNL2,PLEKHO1,CDKL3,RRAGB,ST3GAL6,KIAA1109,IQCG,ZNF44,DENND2A,MSL3,CACFD1,SYNPO,DIPK1A,INPP5B,GIT1,MX1,NASP,NUMA1,PRKAR1B,BCAS3,ZSCAN2,RAD51D,FAT4,ZNF671,RPS6KA2,ATXN7,THSD1,CABIN1,LMF1,NSD2,XRCC4,NDRG4,EMSY,VPS35L" Drug 6071_DN Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "AP2A2,SEMA6A,DOC2A,BCAS1,ATM,BTRC,CA4,CACNA1D,HAP1,ARHGEF2,PICK1,SLC4A8,RCHY1,SIPA1L1,CNTNAP2,FAM169A,DZIP3,SDC3,DBN1,DUSP9,ING4,COQ7,NCALD,ZNF589,KIAA1109,FGFR1,IQCG,GNG3,TDRKH,RASSF8,INPP5B,ITIH2,VWA5A,TM6SF1,MPP2,NF1,PRKAR1B,MAPK7,GRAMD1C,PRODH,NKAIN1,RAB3A,RAB3IL1,SLC1A7,PREX2,SLC6A8,COA1,ZCCHC24,MAPK8IP3,VPS13A,EXOC7,VGF,VIPR2" Drug 6523_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ACTN2,FZD9,AK2,BEGAIN,RGS20,ASPH,CFAP410,CACNA1D,NEURL1,CBARP,CHRNA4,CNN3,AKAP7,CNTNAP2,SPOCK2,HP1BP3,RCAN1,DTNA,PLXNC1,CORO2B,FGFR1,FHL1,FYB1,GAP43,SIGLEC8,RUNDC3A,GNAO1,LPAR4,GRIA1,GRIN2C,NR3C1,GRM7,GRM8,KCNJ5,MAP4,MSI1,PDE4B,GPR85,PTAFR,PTCH1,PEX5,PKNOX2,ARHGEF40,CLSTN2,PLCB1,ZEB1,PCDHGA10,PSD3,SLC44A1,WIPF1,SLC30A3,DNALI1,KCNAB1" Drug 3664_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ASIC1,ACTN1,PLA2G6,AMPD3,APAF1,APBB1,APOC1,CBFA2T2,SEPT7,ARHGAP33,LARGE1,UBE2L6,FOXN3,ZFYVE9,CPS1,PDE4DIP,CDON,ATN1,DSCAM,MBNL2,ING4,MRNIP,LRRC23,STX2,IQCG,PDLIM5,SRCAP,C1QL1,GPR17,GPER1,SPACA9,IL6ST,INPP5B,KCNJ5,KHK,L1CAM,VWA5A,MAN2A2,MEIS1,NDP,CNOT4,NPR2,WDR25,SH3TC2,ENOX1,TCP11L1,WDTC1,LHPP,SS18,ASTN2,KIAA1107,LAT2,MPPE1" Drug 3795_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ACTN2,APBB1,APBB2,APC,ASPH,ATP2B2,CA12,CALB2,KALRN,NEURL1,GPR37L1,TPP1,FAM189A2,ABCG2,NRG2,CSF1,TENM4,PYGO1,TOX,BRINP1,DTNB,RGS17,PDLIM5,NSG1,B3GAT1,GABRA2,ATP8A2,GFER,GFRA1,GRM7,ATXN2L,ITGA7,MAOB,NF1,NPTX2,NRCAM,NTRK3,LRRN3,PROX1,PTAFR,RYR1,SLC15A2,BTBD7,KIF13A,SPTB,NFASC,AJAP1,SEMA4A,TPM1,TPM2,PRDM10,ADAMTS9,KCNAB1" Drug 5994_UP Lymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ADCY2,ADORA2A,KIAA1324,C1QTNF3,LTBP4,BIN1,APBA2,APBB2,CACNA1D,RHBDL1,CD86,CDC42,CHM,FAM189A2,DNAJB5,NECTIN3,NCOR2,GIT2,KBTBD11,ATN1,ELAVL3,C3orf18,VPS13B,ZNF589,GAB1,GABRA5,NEU3,GRK4,GRM1,PRDM5,AFDN,MYT1,NELL2,KCNK10,PCDHGC3,PDE3B,RETREG1,PNMA3,POU6F1,PPP2R2B,MAPK8,WLS,RPH3A,EPN2,LIMCH1,TNIK,SPTB,EPB41L3,VAMP1,SMG6,HEY1,AMOT,GJC2" Drug 5535_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.13E-05 1.00E+00 7.10E-04 8.08E-03 53 200 "ACTN2,ADRA1D,AGT,NME5,SPARCL1,CDK10,PLA2G4C,CADM3,CAMK2B,CBFA2T2,CLGN,RAB28,WHRN,FEZ1,CNTNAP2,EDRF1,SPOCK2,CNIH3,DTNA,DYRK1A,CEND1,SCML2,CORO2B,ZNF589,FHL1,TMEM8B,GPER1,NR3C1,GRM7,KLF12,IPO5,MAN2A2,MX1,NEFM,NF1,NNAT,NPTX2,ODF2,NLE1,MTRF1L,STRN3,PACSIN1,SAMD9,PLPPR1,ITSN1,BTBD7,RBM26,ZFR2,VAMP1,HEY1,TNS1,SMUG1,ZKSCAN5" Drug 6886_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.18E-05 1.00E+00 7.15E-04 8.14E-03 48 176 "ABAT,AK2,ARNTL,ATM,CACNA1I,USP2,ENTPD4,VCAN,PDE4DIP,CTH,DAPK3,DBT,FCF1,EFNA3,TUBD1,EPB41L2,TAOK3,BAIAP2,PDLIM5,CYP46A1,RND1,GLS,GUCY1B1,ACOT7,KIF5C,LSS,MAP2,MAPT,MMP16,SERPINI1,MINDY2,SYTL2,GON4L,PLEKHB2,RGS4,ASAP3,COA1,SOX15,SS18,RGL1,ACSBG1,SYT11,SYT1,HIRA,UBE2H,SH3GLB2,SCG2,SLC17A7" Drug CID000002752 Cinildipine Stitch 6.22E-05 1.00E+00 7.20E-04 8.19E-03 21 56 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,EFS,CACNG3,CACNG2,FCGRT,PKD1,RYR1,RYR3,TPCN2" Drug CID000004494 nilvadipine Stitch 6.24E-05 1.00E+00 7.22E-04 8.21E-03 22 60 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,EDN1,CACNG7,RASL12,CACNG3,CACNG2,NPPA,PKD1,RYR1,RYR3,TPCN2" Drug CID006442852 AC1O5Y0F Stitch 6.27E-05 1.00E+00 7.25E-04 8.25E-03 16 37 "TUBD1,TUBB3,TUBB4A,TUBA8,GFAP,TUBA1C,TUBB2B,MAP2,NEFM,NEFH,RIT2,CLSTN2,SYN2,TUBB2A,TUBB1,TUBA1A" Drug CID000003488 glibenclamide Stitch 6.27E-05 1.00E+00 7.26E-04 8.26E-03 89 382 "RALGAPA1,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ABCD2,APOC1,APOC2,ALDH7A1,CACNA1D,CACNA2D1,CACNB2,CALM1,NGB,CAPN3,KYAT1,KRIT1,SCARB1,LRBA,CHRM1,SLC22A6,CLCN3,CLCN4,ABCG2,ABCG1,CTH,DBI,SACS,ABCC5,ABCC9,EDN1,EDN3,EDNRA,EDNRB,CALCRL,KCNMB2,ABCA8,FGF1,FOXM1,GCK,LYVE1,CRCP,KCNMB4,GPD1,GPD2,GUCY1A2,GUCY1B1,HBA1,CPT1C,KCNA1,KCNA2,KCNA6,KCNB1,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK1,KCNK2,KCNK3,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3,NOS1,NPPA,NPR2,OPRL1,KCNK10,PDE4D,PENK,ABCB1,FTO,PRKACB,PRKCB,PRKCG,RIT2,SST,APOM,ABCC8,KCNAB1,NETO1" Drug ctd:C088658 zoledronic acid CTD 6.33E-05 1.00E+00 7.32E-04 8.33E-03 285 1472 "SERPINA3,ASIC1,NCKAP5,GALNT16,USP31,UNC5A,NLGN4X,KLHL13,CC2D2A,C1QTNF1,BCAR3,BBOX1,SYT13,MRTFA,ANK2,EP400,C6orf89,PKP4,CNTNAP1,API5,ARNTL,PLA2G4C,MARCH3,RASL11B,ATP1A1,SLC4A4,STX16,SLC2A11,N4BP2L1,BCHE,RGS11,BCL2L2,BID,CFLAR,PROM1,SYNJ1,DDR1,CAMK2D,CARS,PRC1,CBR1,CBS,LDB2,FMNL3,SLC16A4,CD86,REPS2,CDC42,GPR37L1,ADGRG1,RCBTB2,SRSF11,CHI3L2,ARHGAP22,STOML1,FADS2,ABCG2,RAB26,AKAP7,COL4A5,COL9A2,ABI3BP,MFSD4A,CP,FAM171B,PNKD,CREB5,CSF1,TENM4,FEZ1,CTH,ARHGEF4,RIMS2,HDAC9,SNPH,ARHGAP24,RIMS3,DAPK1,HP1BP3,LYPD1,RHOBTB1,PARD6A,SRGAP3,AK5,RABGAP1L,ARNT2,DLX1,SLC29A4,CPEB2,ARRDC4,ABCC5,EDN1,FEM1B,RASGRP1,FSD1L,OPTN,APH1A,EBI3,PCOLCE2,ENPP6,SIRPB1,ADGRV1,F3,TBC1D16,TUBA1B,TUBB3,TUBB4A,DLC1,FCGRT,FDFT1,PPP1R1B,FECH,FGFR3,FHL1,HPCAL4,CAP2,PCYOX1,TRIM16,AP4B1,FYB1,SDCBP2,MEGF11,DENND2A,DNER,SESN1,ADAM28,PCDH17,PPARGC1A,MALT1,GJB1,GK,RND1,PSRC1,PRUNE2,EML4,TUBA1C,C1QL4,PLCD4,GRM8,FAM107A,RNFT2,ATOH8,ARHGAP19,HLF,DHX35,IRF8,IGF1,PLD5,LIX1,TUBB2B,ZNF385B,JAK1,JAK2,KCNH1,KLHL23,KIT,STMN1,NCOA7,LSS,PIK3AP1,MAP2,MATN3,MDM4,MGAT3,KITLG,MID1,MYL3,NEFM,NFE2L2,NINJ2,SLC11A2,NRCAM,NTRK2,ZNF827,PALM,PDE1A,PDE4B,PDGFRA,PFKFB4,SEMA5B,PIK3C2A,ANLN,PIK3R1,RETREG1,PLEC,SMOX,PSAT1,PILRA,PPP1R1A,PPP2R2B,CRLS1,PPP3CA,RANBP3L,PRKAB2,PRKACB,PKIA,MAPK3,MAPK8,MAPK10,KLK6,SLC22A23,SYTL2,LAMA1,PTHLH,PTH1R,PTK2,STK32A,PTPN13,CASTOR1,PTPRG,RAB5B,RAD17,RAD51D,RAP1GAP,BEND5,RADX,LGI2,SUGCT,STK32B,LRRK2,KCNIP3,WLS,ATXN1,IL17RB,SELL,GALNT10,SCG5,DOCK10,NTNG1,SHC4,ST6GAL1,ZNF365,SLC1A3,PREX2,SMTN,SLC6A8,SLC14A1,SLC15A2,EFHD1,SLC22A4,OGDHL,SORCS3,LIMCH1,SNAP25,TMCC1,WDTC1,TRERF1,SOX2,SPATA7,FNBP1,KDM3A,IZUMO4,ARHGAP26,TAB2,ATP10B,PBLD,ITPRID2,SSTR1,SS18,NXT2,ST5,RGL1,PHLDB1,SULF2,PLCB1,WSCD1,KIAA0930,ARHGEF12,SPX,CBX5,TMOD1,TNFRSF1B,STXBP4,UGT8,PLEKHH2,PCDH20,ZNF74,NDRG4,TFIP11,WNK1,PRTFDC1,TUBA1A,ADAMTS9,NAV2,ADAMTSL3" Drug DB00189 Ethchlorvynol Drug Bank 6.33E-05 1.00E+00 7.32E-04 8.33E-03 7 9 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug ctd:C551178 PF-04254644 CTD 6.33E-05 1.00E+00 7.32E-04 8.33E-03 7 9 "ALK,FGFR3,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B" Drug CID000003244 AC1L1FHZ Stitch 6.47E-05 1.00E+00 7.48E-04 8.51E-03 56 215 "KLRC4,ALK,APAF1,BACH1,CACNA1A,CACNA1B,CANX,AIFM1,NOG,EPS15L1,CNR1,TRIM69,HDAC9,DYNC1I1,ATN1,DNM1L,EGFR,EN2,ENO2,TUBB4A,PPP1R1B,FOXG1,GFAP,GHR,PPARGC1A,TCERG1,GPR37,PACSIN2,HP,HPR,HSP90AA1,IGF1,PACRG,NACA,NOS1,OGG1,OPA1,PAH,PENK,ABCB1,PACSIN1,MAPK9,MAPK10,PSMA6,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SNAP25,SNCA,SIRT1,TLR4,UBC,PRTFDC1,JPH3" Drug CID000014044 allylglycine Stitch 6.50E-05 1.00E+00 7.51E-04 8.54E-03 14 30 "ABAT,NFS1,CTH,BOC,FCGRT,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GRIA2" Drug CID000065863 sertaconazole Stitch 6.55E-05 1.00E+00 7.57E-04 8.61E-03 57 220 "SERPINA3,SYN3,SPARCL1,ALCAM,APBA2,ARNTL,ASTN1,SYNJ1,CA4,CANX,FADS2,BLOC1S6,NRG3,GAD1,GAD2,DISC1,MCHR1,GRID1,FAM107A,AGFG1,KCNN3,MAPT,MBP,MOBP,BLOC1S2,MXI1,PCDHGC3,PCMT1,PDE4B,SERPINI1,POLR2F,PPP2R2B,PPP3CC,PRODH,RELN,RAD17,RPL38,ST6GAL1,SMARCA4,SNAP25,SNCA,RHBDL3,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,NPL,PDSS1,HIRA,ETNPPL,POLR3H,SLC30A4,PRDM2,RTN4,HNRNPA3" Drug CID000003008 racemethorphan Stitch 6.58E-05 1.00E+00 7.60E-04 8.64E-03 33 107 "AMT,CACNA2D1,ASIC3,WDR20,GRIN3A,DMPK,MRO,SEMA4D,CYP46A1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,CIT,OPRL1,PDYN,PENK,ABCB1,MAPK7,AP1AR,SCN4B,SCN3B,TRPC3" Drug 6286_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.58E-05 1.00E+00 7.60E-04 8.64E-03 50 186 "RALGAPA1,ASPHD1,GRAMD1B,ALAD,APC,EPB41L5,CFLAR,SCAPER,IL33,MAP7,ARHGEF1,ARHGEF2,KCNAB3,QKI,WHRN,CREM,CSNK1E,VCAN,CTH,PITPNC1,LYPD1,DSCAM,ELN,COQ7,DMTN,RRAGB,FGFR1,C1orf61,TBR1,GAD1,HBS1L,SIGLEC8,ZNF276,NF1,CNOT4,SMOX,CEP41,PTCH1,PTHLH,RAB3A,MYH14,SH3BP2,PHLDB1,KIAA1107,TBL1X,TEX15,TIAM1,NDRG4,NT5M,PHTF2" Drug 6672_UP Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.58E-05 1.00E+00 7.60E-04 8.64E-03 50 186 "ACHE,KIDINS220,AMT,LGR5,CDC14B,CBS,CBFA2T2,MAGI1,NRXN3,HOMER3,SLC4A7,PDE4DIP,CTH,RUSC2,DSCAM,DUSP9,EDN1,ELAVL3,EPHB1,ATP8A1,CSPG5,RND1,CACFD1,GRM7,GSN,ITGA7,KCNJ5,MGAT3,ADAM22,MSR1,NTRK2,PCDH9,PDE4B,PENK,LRRN3,PTPRG,GAL3ST4,RGS4,RGS12,HKDC1,SLC2A5,RIMS1,SOX15,KDM4C,DAAM2,AMOT,LAT2,PMEPA1,PRDM2,KCNAB1" Drug 4380_UP CP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.58E-05 1.00E+00 7.60E-04 8.64E-03 50 186 "DDO,APOC1,CFAP410,CDH2,CNTN1,RGS6,ARHGEF10,PDE4DIP,CNTNAP2,CTIF,ELMO1,DTNA,SGK2,LRRC17,APC2,KHDRBS3,FYN,GABRG2,GLS,PCLO,CACFD1,SOX21,HLF,KCNJ5,KCNMA1,LMO2,LSS,MAP2,PCDH9,CDK18,PFKFB2,SERPINI1,PIK3CD,SMOX,SMIM7,KCNIP1,SMPD3,SH3GL3,ASAP3,SLC2A5,FAM214B,BTBD7,KDM4B,ZCCHC24,ELOVL4,RGL1,ABCC8,VAMP1,SLC30A3,SLC17A7" Drug 1607_UP Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; HL60; HG-U133A Broad Institute CMAP Up 6.69E-05 1.00E+00 7.72E-04 8.79E-03 46 167 "NDRG2,ADD3,ALAD,GAS7,ARRB2,DNAH17,CFLAR,ST3GAL5,CD86,CD38,FOXN3,CHN2,CREM,SIPA1L1,VCAN,PPP1R16B,DOCK4,ZFYVE16,SIDT2,FAM13A,MBNL2,ING4,AMZ2,PACSIN2,OLR1,PDE3B,PDE4B,PDE4D,GPSM2,SMOX,BSDC1,SGK1,SLA,ARHGEF40,ELMO2,MAPKBP1,ZSWIM8,BEX1,SPTAN1,SAMSN1,EPB41L3,PLCB1,TCF4,TK2,TPM4,FLRT2" Drug CID005289285 Reidispongiolide C Stitch 6.73E-05 1.00E+00 7.77E-04 8.84E-03 69 280 "AXIN2,SLC12A5,SEMA6A,ALCAM,NRP2,CALB1,CALB2,CDH2,NUMBL,JAM2,VAX2,MAP4K4,CNTFR,DCC,HEPH,DSCAM,EDN1,HIPK3,OPTN,EFNA2,EFNA3,EFNB3,EPHA5,NRN1,TAOK3,FGF1,FOXG1,WASF3,MSTN,GFAP,GRIK1,GRIN2C,GRIN2D,LINGO1,KCNA1,KCNA6,KCNC2,MAG,MARK3,MEIS1,MOG,NCAM1,NEFM,NEFH,NHLH1,NPPA,NPR2,NTRK2,NTRK3,OMG,OPA1,GPSM2,PMS2,ROBO2,TNFRSF19,SLC1A2,SLC1A3,SLC1A7,SPP1,CNTN2,WDR7,THBS4,ZFP91,TNFRSF1B,VSNL1,ZIC1,ZIC2,RTN4,NUP214" Drug ctd:D012402 Rotenone CTD 6.75E-05 1.00E+00 7.78E-04 8.86E-03 199 983 "ACHE,ADAR,ADORA2A,MTA3,AGT,TBC1D14,APAF1,GAS7,GPAM,APP,ARHGDIG,ARNTL,ATM,ATP1A2,ATP2B2,KIF1A,BARD1,BCL2L2,BID,PROM1,WASF1,BTRC,CALB1,CALB2,CAMK2A,CAMK2B,CAMK2G,CBS,CCNH,AIFM1,CD38,ENTPD2,CD81,CDC42,CPNE6,CLU,NMT2,DNAJB5,NIPBL,CNTN1,COX4I1,CP,CRMP1,CRY2,SNCAIP,CSF1,CTH,PPP6R2,FAM131B,CYBB,DAPK1,DNAJC6,HEPH,FBXL5,C2CD2L,SV2B,DRD1,PDCD6IP,DNM1L,FIS1,EDN1,OPTN,RBM12,EFNB3,PHF20L1,EGFR,CALCRL,EN2,TUBD1,RASGRP2,RPS6KC1,TUBA1B,TUBB3,TUBB4A,TAOK3,CEP78,FGF1,SUCO,SYNCRIP,FLT1,USP21,CAMKK2,ZMYND11,TUBA8,GFAP,GFRA1,PPARGC1A,TTBK1,RND1,EML4,TUBA1C,RAPGEF4,NR3C1,GRM5,GRM7,GRM8,HBA1,ZHX1,HMGCR,MSL1,IDH3A,IDH3B,IGF1,TUBB2B,ITGAM,JAK1,JAK2,KCNH2,KCNJ4,KIF5A,LAMP2,MAPT,MBP,MSR1,MT3,NACA,HNRNPM,NASP,NDUFA5,NFE2L2,ALDH1L2,NNAT,NPY,NTRK2,ODF2,OPA1,OPHN1,CLDN11,PCMT1,CDK18,PDE3B,PGAM2,ABCB1,SERPINE2,PPP2R2B,MAPK3,MAPK8,MAPK9,MAPK10,PTPRD,PTX3,RAB3A,RAD17,ATG16L1,RET,SUGCT,GSTCD,FBXW7,MCMBP,LRRK2,AP1AR,TNFRSF19,CASC3,ASRGL1,SGK1,PPP1R9A,SH3GL2,AMBRA1,PREX2,RUFY2,SLC6A8,RAB3GAP1,CXXC4,SNCA,CABCOCO1,FNBP1,SPP1,KIF1B,CNTN2,TEK,ATP13A2,DNAH7,SIRT1,CHST8,THRA,TIAM1,TJP1,TK2,ZFP91,TNNT1,CDK20,TRPC1,TRPC3,TRPM2,TUBB2A,RPL7L1,UCHL1,UGT8,PDIA2,VLDLR,WNT7A,NPDC1,TFIP11,TUBA1A,UBE3B,CAMK1G,NLRP3,SSPN,CBLN2" Drug 1561_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 6.76E-05 1.00E+00 7.79E-04 8.86E-03 51 191 "ADD3,ARNTL,MARK4,ST3GAL5,WASF1,CAST,CHRNB2,FEZ1,PPP1R16B,CX3CR1,DOCK4,DBT,EFNB3,FAM13A,ABI2,LPAR6,GOLGA7,ENO2,RASGRP2,EPS8,FGFR1,GABRA4,HBS1L,DBF4,HTATSF1,AGFG1,IFI16,ITGA7,ITGAM,MEF2C,NRGN,CCSER2,SLC25A23,PTK2,PTX3,SEC14L1,ELMO2,SPATA7,ZCCHC24,CDK19,SAMSN1,CEP68,STXBP1,KLHL7,TACC1,PDLIM2,TPM1,DNAJC12,PRDM2,EVI5,LMAN2L" Drug 6008_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.76E-05 1.00E+00 7.79E-04 8.86E-03 51 191 "DPF1,SERPINA3,NR0B1,GAS7,CDK10,SCAPER,BTRC,CACNA2D2,SOCS6,TPP1,CNTFR,SMARCAL1,TCEAL2,NECTIN3,INTS1,DAPK1,GNE,EDNRA,TNK2,COQ7,RASGRP2,NCALD,ZNF391,FAM49B,FYN,ALDH1L1,RND1,GPM6B,STMN2,ATXN2L,KCNJ5,MSI1,OPCML,PDE4B,GPR85,PENK,PIK3CD,KHDRBS2,TCP11L1,SBF1,SEC14L1,SLC2A5,SMARCD3,KDM4C,POPDC3,TRIM2,ZNF34,VLDLR,PRDM2,MVB12B,GJC2" Drug 6390_DN 5707885; Down 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-05 1.00E+00 7.79E-04 8.86E-03 51 191 "LTBP4,CDC42BPA,APBB1,BCAS1,ARRB1,SCAPER,RUNX1T1,CLCN4,IQCK,CRMP1,ABCG1,SEC14L5,RIMS3,MFAP3L,FGFR1,PNMA2,ZMYND11,TMEM8B,ALDH1L1,SRCAP,HAS2,SCIN,IL6ST,INPP5B,KIFC3,MEF2C,LYRM9,CDK18,PDE1C,PGAM2,PLXNB1,CEP41,ELOVL2,PTPRD,RGS7,SCG5,FBXO11,DZIP1,SLA,SLC1A3,BTBD7,ZNF667,CEP68,TCF4,OBSL1,TMEM121,TNS1,SPHK2,MAP3K12,SEMA3B,KCNAB1" Drug 7154_DN Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.76E-05 1.00E+00 7.79E-04 8.86E-03 51 191 "ARNTL,MARK4,AKAP7,TENM4,DZIP3,ARHGAP32,KIAA0513,PARD6A,DLG3,DNM2,EIF5,RGS17,VPS13B,F8,ZNF589,FGFR1,GLS,DIDO1,GSN,KHK,MEIS1,MMP16,TAGLN3,ZSCAN32,RGS4,ZNF671,CSRNP3,ZNF365,BTBD7,SLC20A2,KDM4B,TNIK,ARHGAP26,ZC4H2,STX1A,ARHGEF9,KIAA0930,TCF7L2,TRIM2,ARHGEF12,TNS2,TMEM121,HEY1,KAT6B,TRPC1,NPDC1,TRIM9,NDRG4,HPS4,FZD3,SENP7" Drug ctd:C412815 GW 4064 CTD 6.91E-05 1.00E+00 7.87E-04 8.95E-03 101 446 "SERPINA3,KCNH8,C1QTNF3,GAS7,SEMA4G,PPP4R4,PDXK,NCOA1,ASTN1,ST3GAL5,RUNX1T1,SCARB1,SLC22A6,DLGAP3,CNTFR,ABI3BP,CSF1R,SNAP91,KBTBD11,DOCK2,EDN1,SGK2,CNNM1,HEYL,RASGRP1,ENPP6,ERBB4,ADGRA1,MEGF11,IP6K3,GATM,TTBK1,GLDC,CNDP1,GSN,MFSD2A,TMEM179,UBE2QL1,PADI2,VSIG4,HNMT,IGFBP1,LRRC25,ITGAM,KCNJ4,GATD1,KIF5A,NCOA7,SMAD9,PIK3AP1,SYT9,MX1,MYH3,RTL5,NOS1,CLDN11,PC,PCDH8,ENPP2,DUSP26,SEMA5B,JAKMIP1,NECAB2,FA2H,PPARA,PPP2R2B,LRRN3,MAPK8,MAPK9,STK32A,PID1,RFX5,LGI2,EMID1,KCNIP3,HKDC1,SLC2A5,SHANK2,SLCO1A2,LGI3,CDK5RAP2,PDZD2,CLSTN2,APOM,ADHFE1,TAC1,SATB2,WDR7,SLC19A3,HIF3A,VWCE,TF,ICAM5,TRPC3,KCNE5,RPRM,SLC13A3,ETNPPL,ZBTB16,CAMK1G,PIANP" Drug 4409_DN Alcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AP2A2,APBA2,PDE8B,CADM3,KIF1A,ST3GAL5,CA4,CA12,CAMK2G,LHX2,BAG4,SIPA1L1,RIMS2,RIMS3,SPOCK2,ZNF804A,DMPK,ERCC2,BAIAP2,CAMSAP1,FHL1,FOXG1,FAM49B,GCNT2,C1QL1,KIT,KPNA5,MOBP,ZNF862,NEUROD1,RETREG1,MAPK7,C1orf54,RGS12,SBF1,SH3BP2,EPN2,WDTC1,UNC5B,AJAP1,PLCB1,SEMA4A,WSCD1,TCF7L2,ARHGEF12,DICER1,TRPC1,HIRA,SPHK2,SLC17A7,WIPF2,KAT6A" Drug 4191_UP Conessine [546-06-5]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NLGN4X,ALK,APC,CDC14B,B3GALT2,ADGRB2,FUBP1,BTRC,CACNA2D1,ENTPD2,CHRNA4,FAM149A,IFFO1,PDE4DIP,CTNND2,SRGAP3,DUSP9,SIDT2,SRPK3,NCALD,APC2,SEMA6C,ZNF44,SIGLEC8,GFRA2,GPR75,GNAL,GPR17,AP4S1,KLF12,IGFBP1,KCND3,LSAMP,MAP2,AFDN,LYRM9,DDR2,PDE4B,PLPPR1,RPS6KA2,SCN3A,NTNG1,PREX2,ZNF334,TNIK,KIF21B,PDLIM2,RPGRIP1L,DOCK9,DAAM2,WNK1,SLC17A7" Drug 3387_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "FZD9,NME5,ANK1,GAS7,LDLRAD4,CA12,CACNB2,CDH8,IFFO1,SDC3,NTM,FRY,ERCC2,CEND1,TUBB4A,FOXG1,C1orf61,CAMKK2,GPM6A,NR3C1,ICA1,JAK2,KCNH2,LAMA2,MEF2C,MSR1,TAGLN3,NF1,NPTX2,PCDHGC3,PDE4B,CEP41,MAPK8,RGS10,CARF,IL17RB,SH3GL3,FNDC3A,CXXC4,PEG10,ARHGAP26,ATP10B,POPDC3,HEY1,PARD3,PIK3R5,UBE3A,FLRT2,ZBTB14,PHTF2,NUP214,SENP7" Drug 6460_DN Florfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "OSBPL1A,PLA2G6,AMH,AMT,APOC1,RIPK1,ARHGEF7,LDLRAD4,CA12,CLU,ABI3BP,BAG4,NECTIN3,USP6NL,ARMCX2,EFNA3,IRAK4,COQ7,SCML2,FAM49B,GPR153,DISC1,FERMT2,STON1,BTN2A1,HNMT,IPO5,ZNF862,NF1,NPTX1,ODF2,PIK3CD,RETREG1,FSD1,SYTL2,ELOVL2,CEP97,RAD52,RAP1GDS1,RGS10,RGS12,SEC14L1,SS18,IQCE,KIAA0930,PSD3,BEX4,SSBP2,ZKSCAN5,LMF1,MPPE1,SSPN" Drug 6420_UP Orlistat; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,ADCY6,ADRA1D,MTUS1,APC,APOC1,ARRB2,CDK13,MARCH3,CDK5R1,CACNA1A,CDC42,CDH2,SRSF11,CLCN3,CLCN4,NECTIN3,CPS1,SEMA3D,EGFR,ETV1,BAIAP2,DISC1,GLYR1,FERMT2,GPM6B,DHX35,ITIH2,KCNH2,KCNMA1,MIA2,CD200,GIT1,MX1,NDUFA5,CNOT4,PFKFB2,SNRK,C1orf54,MCMBP,MAPK12,SCN3A,ZFP30,SH3BP2,BEX1,SYT1,ARHGEF12,THRA,CADM1,MAP3K12,MPPE1,FZD3" Drug 1978_UP Prednisone [53-03-2]; Up 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "SPOP,ASPH,KRIT1,SRSF11,NIPBL,SLC4A7,ZEB2,HP1BP3,FBXL5,KCTD3,EPB41L2,STX2,FKTN,SEC23B,EFCAB2,ATP2C1,HBS1L,GART,GLS,HTATSF1,OS9,IRAK3,HSF2,KTN1,LAMP2,MARK3,NINJ2,NTRK3,NUCB2,RETREG1,PMS2,PPM1B,PPP3CB,RAP1GAP,ATXN7,CHD9,KBTBD4,UNC5B,IQSEC2,SPART,SS18,NSFL1C,KLHL7,SYN2,TCF4,DMXL2,NPL,ZMYND8,HIRA,UBE2H,EVI5,HPS4" Drug 2884_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ASIC1,AP2A2,APLP1,PPFIA3,RUNX1T1,CDO1,B4GALT6,FHL5,RIMS3,GSDME,CELSR3,TNK2,HSD17B14,TUBB4A,FGFR3,BAIAP2,AGAP2,SRCAP,DIDO1,BTN2A1,HPSE2,ICA1,KCNH2,KIT,ADAM22,PCBP3,NUMA1,MINDY2,RAB5B,RAD52,TRIM68,EMID1,SCN8A,SLC30A10,SELL,RASA3,NTNG1,SLC9A5,LIMCH1,SNCA,KIF21B,SOX15,VAMP1,ARC,SYN2,WSCD1,KIAA0930,NDRG4,MAP3K12,GDPD5,MVB12B,ADAMTSL3" Drug 2280_DN Ethosuximide [77-67-8]; Down 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "C1QTNF3,APBA2,APBB2,GAS7,APOC1,PLA2G4C,MARK4,NUMB,RASL11B,CFLAR,CFAP410,ARHGEF2,ZFYVE9,HOMER3,RIMS2,DTNA,EGFR,PLXNC1,KIAA1109,FGF12,FHL1,GPR153,GCNT2,SRCAP,POLL,GRIK5,CACFD1,VWA5A,KITLG,MMP16,NPR2,CDK18,RETREG1,RAB3IL1,KLHDC8A,SBF1,ZNF821,SH3BP2,BCAN,SYBU,PEX26,SLC22A4,LIMCH1,SPART,TROVE2,STX1A,ARC,KAZN,TRIM2,PLPPR2,MICAL1,HPS4" Drug 7027_DN (-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,NDRG2,APC,APOC1,PPFIA3,CDK5R1,CBFA2T2,REPS2,NCOR1,ABCG1,DZIP3,CTH,PPP6R2,C2CD2L,LYPD1,MED12,APH1A,RGS17,STX2,EXTL2,SEPT9,MSL3,RNFT2,KIF5C,NF1,NRGN,STRN3,MBOAT7,MED1,PRKAR1B,TMEM104,PTPRG,RGS10,MAPK12,SH3BP2,ITSN1,DOP1A,ZHX3,SPTAN1,CDK19,ZBTB43,CEP68,ANKRD12,MCF2L,NSD1,PCDHA6,TMEM121,CADM1,TFIP11,GDPD5,TIGD6,AAAS" Drug 2784_UP Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "DPF1,ASIC1,ALCAM,AMPH,CDC42BPA,PPFIA3,ATP2A2,SGCE,CALB1,CACNA2D2,RCBTB2,TAOK2,NECTIN3,DCAF4,NOS1AP,C2CD2L,PARD6A,MAMLD1,EFNA3,TNK2,HSD17B14,F5,BAIAP2,C1orf61,DLL3,GAB1,GAD2,ATP8A2,GCNT2,GNG3,GSN,GSTM5,ITPKB,KCNQ3,GIT1,PLCD1,NECAB2,RELN,PTHLH,ZSCAN2,RAB3A,RAB3IL1,C1orf54,RPS6KA2,ZNF821,SNCA,MAPK8IP3,SEMA4A,TRIM2,TK2,TRH,SPHK2" Drug 4389_DN Sulpiride [15676-16-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADORA2A,SEMA6A,LTBP4,AMT,APC,APLP1,CFLAR,MTMR3,CACNA1I,ARHGEF2,CDC42,DNAJB5,RIMS2,PPP6R2,RIMS3,RUSC2,SMG7,HIPK3,HSD17B14,PLEKHO1,FGFR1,PRELID3A,GAB1,SRCAP,AHDC1,C1QL1,PRRC2B,GRM1,ICA1,TJAP1,CNOT4,NTRK2,LRP12,PRKAR1B,PTHLH,ZSCAN32,ZSCAN2,TMEM231,KCNIP1,SH3BP2,ASAP3,KDM4B,ZCCHC24,PHLDB1,KAZN,WSCD1,PSD3,ZKSCAN5,HIRA,SF1,EMSY,MPPE1" Drug 7184_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AK2,MRTFA,APOC1,ADAM15,BCL7A,CFLAR,SYNJ2,GYG2,BAIAP3,CA4,SCARB1,AP4M1,CACNA2D2,RAB28,LRIG1,PDE4DIP,RASSF2,DAPK3,GIT2,HP1BP3,LYPD1,SMG7,RCAN1,EML1,HSD17B14,DLC1,FHL1,SEMA4D,ZNF44,SIGLEC8,DISC1,SLC2A6,ACOT7,KCND3,NFYA,NPR2,NPTX1,PKN2,PTN,WLS,BTBD7,CDK5RAP2,SNCA,EMC1,SPTAN1,CLASP2,SS18,MAPK8IP3,STX1A,ZMYND8,VIPR2,SEMA3B" Drug 5734_DN Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADD2,AP2A2,NME5,APBA2,SEMA4G,ATM,SCAPER,CDC42,CHN2,SULT4A1,CREB5,CSF1,EDRF1,DCAF8,GIT2,MFAP3L,EZH1,TRAF3IP2,ERAP1,ZNF276,GNG4,FERMT2,CNTRL,IL12A,MAPT,TM6SF1,NF1,CNOT4,SERPINI1,NLE1,FSD1,MAPK7,PTPRN2,RAD52,GAL3ST4,RPS6KA2,PAQR6,ITSN1,AMBRA1,KBTBD4,SMARCD3,SNCA,KDM4C,ARHGAP26,SS18,PHLDB1,TCF4,HIRA,VGF,LMF1,KLC2,WNK1" Drug 3032_DN Fluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "APOC1,AZGP1,BACH1,SCAPER,LDLRAD4,CAPN3,HIP1R,SLC16A4,B4GALT6,STOML1,QKI,DBN1,RUSC2,EXOG,DTNA,F5,ST3GAL6,FER,FHL1,PDLIM5,GABRA2,GABRA4,LILRA2,GRM7,ATXN2L,ICA1,TJAP1,KHK,MGAT3,AFF1,N6AMT1,NF1,NINJ2,PDE4B,MAPK9,PTCH1,RAP1GAP,NEK11,FAM214B,SLC20A2,SS18,MAPK8IP3,ADGRL3,TCF4,TCF7L2,TNNT1,RBFOX2,TPM1,ZMYND8,LAT2,ZNF225,NLRP3" Drug 3923_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "BEGAIN,TRMT9B,BIN1,CADM3,CACNA1I,CACNA1G,CFAP410,KALRN,RUNX1T1,CD86,NEURL1,CHN2,RAB33A,VCAN,DOCK2,USH1C,ELAVL3,TNK2,FGF1,FGFR1,FHL1,SORBS1,C1QL1,GPR22,GRIA4,HRH3,IGF1,KCNB1,MID1,NEUROD1,NPPA,NTRK2,NTRK3,SNTG1,PIK3CD,PRKCB,ENOX1,ST6GAL1,PKNOX2,NMNAT2,CDK19,COLGALT2,SYT11,SYN2,TAL1,HIF3A,SEZ6L,CHST5,TRH,TRO,VSNL1,KCNAB1" Drug 5007_UP Methoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NDRG2,ADRA1D,MRTFA,CDC42BPA,PPP4R4,CDK13,MARK4,CFLAR,CACNG1,CAMK2B,CANX,CCKBR,UBE2L6,CLCN4,CNTN1,AKAP7,SIPA1L1,ARHGEF4,TBC1D5,DBN1,HP1BP3,SV2A,HIPK3,FHL1,FOXG1,OGA,GLYR1,EML4,GRM2,KCND3,KCNQ3,KIF5C,KITLG,ADAM22,PDE3B,PACSIN1,PKN2,MAPK8,ASAP3,BCAN,LIMS2,SLC6A8,WDTC1,TSNAXIP1,HECW1,NXT2,PLCB1,KIAA1107,SZT2,LILRA4,AMACR,PHTF2" Drug 2961_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ARID1A,BIN1,ANK3,SLC4A4,MYRF,BTRC,CACNA1A,ARHGAP33,ZFYVE9,DNAJB5,WHRN,CLOCK,CREM,CSNK1E,CTNND2,ZNF337,DYRK1A,FAM13A,ABI2,MRNIP,VPS13B,PTK2B,FOXG1,CGREF1,SYT17,ALDH1L1,ZNF276,RND1,IL6ST,MAP4,AFDN,OXTR,CCSER2,PLCB2,PLEC,MARCH1,BEND5,RGS12,SEC61A2,ZNF821,FAM102A,DOP1A,IZUMO4,PEG10,ZC4H2,PDLIM2,TBCEL,RBFOX2,BEST1,ZFP37,EPM2A,PHTF2" Drug 2317_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NME5,CFLAR,GYG2,CLGN,QKI,CNTN1,AKAP7,CABP1,CNTNAP2,RIMS2,DCAF4,RIMS3,DCT,DSCAM,DUSP9,ABCC9,EDNRA,HIPK3,EGR3,VPS13B,RCAN2,LRRC17,RASGRP2,ERCC2,SPEG,APC2,ZNF589,FGFR1,FYB1,GLS,HPSE2,ITIH2,ITPKA,L1CAM,SMAD1,MGAT3,CD200,ADAM22,CLDN11,GDAP1L1,PIK3CD,RELN,FAM120C,RAB3IL1,CCDC40,RAD52,SH3GL3,ASAP3,CXXC4,WSCD1,RPGRIP1L,HEY2" Drug 6053_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AMH,GAS7,PLA2G4C,DNAH17,GYG2,CLGN,CHM,CHN2,EPS15L1,WHRN,ARHGEF10,MICAL2,CYBB,SPOCK2,MFAP3L,GSDME,DYNC1I1,EDNRA,HSD17B14,RUNDC3A,HPGDS,GRM2,SOX21,PTGDR2,ATXN2L,ITGAM,KCNN1,NEUROD1,OMG,CLDN11,LRP12,MAPK7,SCN8A,SELL,MRAS,PEX26,SLC9A5,SLC11A1,SHANK2,SMARCD3,SNAP25,WDTC1,ATP10B,NXT2,AJAP1,ARC,TBCEL,DOCK9,HEY2,LAT2,SLC30A3,EMSY" Drug 1770_UP Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "PDE8B,SLC4A4,CADM3,ADGRB2,MYRF,CA12,CACNA1A,CALB2,SPAG9,NEURL1,CHN2,CNTFR,AKAP6,COL9A2,CTIF,TMCC2,TRAPPC9,ATN1,DSCAM,SGK2,SORBS3,TUBB4A,TRMO,GAP43,GLS,SPACA9,CACFD1,KCNF1,LAMA2,MBP,GIT1,NPPA,OMG,KCNK10,DUSP26,PACSIN1,PPARA,PPP5C,CCDC40,RGS3,RNASE1,RXRA,LIMS2,SLC6A11,SLC11A1,IZUMO4,CRTC1,DNAH7,LILRA4,TRPM2,VGF,VIPR2" Drug 6635_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NME5,AMT,CDC42BPA,LGR5,MARK4,ATM,SLC4A4,CFLAR,CFAP410,HOMER3,PICK1,WHRN,CREM,SH2B1,DZIP3,EDRF1,HDAC9,CTIF,DBT,DLG3,EFNA3,SORBS3,PLEKHO1,ETV1,EZH1,C1orf61,GAB1,DENND2A,C1QL1,GPR37,MDFI,MDM4,ADAM22,NFIX,POLG,GRAMD1C,RAD52,RPS6KA2,PPP1R9A,BCAN,ANKRD6,SLC1A7,CCDC88A,SNCA,KLHL4,ARHGEF12,PARD3,RPRM,NSD2,KLC2,SCG2,PHTF2" Drug 1155_UP 2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,MTUS1,AGT,PLA2G6,ANK3,APBB2,ARNTL,ST3GAL5,SLC16A4,FEZ1,SLITRK5,DOCK4,DAPK1,RUSC2,DTNA,MBNL2,SORBS3,EXTL2,F5,GABRA2,GAD2,SEPT9,INPP5K,ALDH1L1,RAB40B,GPD2,LILRA2,IL11RA,ITGA7,SCAMP5,CCSER2,SIDT1,PTN,PTPRN2,RGS10,WLS,SATB1,ANKRD6,SLC1A7,DBNDD2,ZC4H2,TCF4,SLC44A1,TMOD1,TNNT1,RBFOX2,TPM1,TRPS1,NPDC1,ZNF32,PHTF2,ACTR3B" Drug 4722_UP Merbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "DPF1,ASIC1,ALCAM,AMT,EPB41L5,PLA2G4C,CFLAR,BAIAP3,CAMK2G,RUNX1T1,ARHGEF1,CSF1,GREB1,SPOCK2,GIT2,C2CD2L,EDN1,EFNB3,TNK2,NCALD,FGFR1,CAMSAP1,OGA,GALC,ALDH1L1,GLYR1,TDRKH,KLF12,ITGA7,KCND3,KCNH2,KCNJ3,KCNJ4,KIF5A,VWA5A,AFDN,MMP16,MMP17,NPR2,NKAIN1,CCDC40,RGS12,KCNIP1,CNKSR2,LIMCH1,SMG6,OBSL1,TNS1,LAT2,WNK1,ITM2C,JPH3" Drug 2950_UP Roxarsone [121-19-7]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ACTN2,ADCY2,ADRA1D,AMPH,PKP4,ALDH4A1,KIF1A,HIP1R,SCARB1,MAGI1,CLCN4,HOMER3,CNTN1,DZIP3,CTNND2,DBT,DCTN1,KLHL3,CDON,RASGRP2,CAMSAP1,FHL1,GPR153,KCNMB4,ATXN2L,HNMT,GIT1,FAM120C,PTPRZ1,MYH14,TCP11L1,RYR1,TRIM46,RASA3,ST6GAL1,SNCA,PALLD,TMCC1,SPTAN1,SPTB,JMJD6,PDLIM2,WWC1,SZT2,CHST8,ZNF34,TJP1,TRPS1,KCNE5,LMF1,SLC13A3,GDPD5" Drug 5799_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "KLRC4,AGT,GAS7,RASL11B,ATP1A2,KIF1A,ADGRB2,CACNA1I,INA,SCARB1,CHN2,CRMP1,ARHGEF4,DLG4,DTNA,ING4,EPHB1,FABP7,C1orf61,PDLIM5,PRELID3A,FYB1,GABRA5,NEU3,GNAO1,GNG4,GRIK1,SPACA9,LMO1,VWA5A,MYL3,PCBP3,PDE2A,PDGFRA,EPN1,POU6F1,ZSCAN2,C1orf54,RGS12,TCP11L1,OGDHL,KIF13A,ZSWIM8,ACSBG1,MCF2L,KIAA1107,TCF4,SZT2,DOCK9,TEX15,BHLHB9,NUP214" Drug 4567_UP Cefixime [79350-37-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "PLA2G6,GAS7,ZSCAN18,ATP2B2,NRP2,LDLRAD4,BTRC,CACNA1D,SLC16A4,ARHGEF2,NRXN2,IFFO1,CREM,CTIF,PLPPR4,EDN3,EIF4G2,ELN,MTSS1L,CEND1,CORO2B,BAIAP2,FOXG1,B3GAT1,ZNF44,ARPP21,RUNDC3A,PRUNE2,GRIN1,GRM2,KLF12,ITGA7,VWA5A,MSI1,ADAM22,NCAM1,NELL2,NF1,NOVA2,PCBP3,RGS10,FBXW7,RTN1,SEMA6D,SLC6A9,TROVE2,SZT2,RALYL,FAM189A1,TEX15,OSBP2,HRASLS" Drug 2262_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "TRMT9B,ANK1,SEMA7A,PRX,SPTBN4,SLC2A11,CFLAR,KSR1,CACNA1D,CD86,TCEAL2,CNTNAP2,GREB1,DCAF4,C2CD2L,MAGI2,SMG7,DMPK,EDNRB,EIF4G2,EFS,TUBB4A,ZNF589,SCARA3,C1orf61,GABRA4,RUNDC3A,HRH3,HPSE2,IL6ST,MEF2C,MMP16,KCNK10,PALM,PDE4D,CDIP1,LRRN3,RAB3IL1,C1orf54,DOCK10,SLC1A2,SLC4A3,SLN,SPP1,TCF7,TNS1,TPM3,TRPC1,UCHL1,FLRT2,XRCC4,PHTF2" Drug 328_DN LY294002; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ACLY,PPFIA3,CADM3,C5,CDH18,CHRNB2,IFFO1,GREB1,DCAF4,KLHL3,G3BP2,DUSP9,SUGP2,DMTN,LRRC23,TBR1,GABRA4,GAD2,C1QL1,RAB30,GNAO1,GPR12,ADAMTS13,SOX21,KHK,MAP4,MEIS1,FXYD6,OPCML,PRKAR1B,LRRC49,MAP6D1,FOXRED2,SH3BP2,SH3GL3,FNDC3A,PREX2,SLC11A1,SNCA,TNIK,EMC1,JMJD6,ATP11A,SLC35G2,TF,THBS4,ZMYND8,TMPRSS5,AMOT,VAV2,SLC13A3,UPF3A" Drug 3534_DN Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "KIDINS220,CDC42BPA,ATM,CFLAR,SYNJ2,SOCS6,SULT4A1,AKAP7,BAG4,CSF1,PDE4DIP,GREB1,RUSC2,SMG7,EFNB3,MBNL2,EN2,VPS13B,COQ7,POLR1B,FLNC,TDRKH,GRIK5,KCNJ3,MITF,MPP2,NF1,NPTX1,ODF2,OPCML,PALM,PIK3R1,RETREG1,PRKAR1B,PRODH,RGS10,MAP6D1,PAQR6,SEMA6D,SBF1,SLC20A2,RBM34,SPART,POPDC3,ATP11A,ROBO3,MCF2L,EHBP1,TRIM2,TMEM121,RUNDC3B,REEP1" Drug 3222_DN Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,PLA2G6,ARHGDIG,RGS20,CDK5R1,SCAPER,USP2,QKI,COL9A2,SDC3,MFAP3L,EDNRA,MBNL2,SORBS3,DMTN,GABRA2,USP19,MALT1,NR3C1,HNMT,HSD17B1,LIG4,MAP4,KITLG,MMP16,PCDH9,MAPK8,RAD52,ZCWPW1,RGS12,ARHGEF10L,EMID1,ITSN1,ZKSCAN3,SMARCD3,MAPKBP1,ZCCHC24,IQSEC2,THSD1,PLCB1,ASTN2,ATP11A,SEMA4A,IQCE,TNS2,CHST8,HIRA,VIPR2,LMF1,MPPE1,EPM2A,UBE3B" Drug 5276_DN "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AK2,MRTFA,APC,CDK10,SEMA4G,DNAH17,MARK4,ATM,CFLAR,CACNA1D,CDH8,CNTN1,AKAP7,CRY2,PDE4DIP,NOS1AP,RASSF2,JAKMIP2,MFAP3L,EXOG,EGFR,MBNL2,PIPOX,DLC1,FGF13,C1orf61,OGA,GAB1,GAD1,GNG4,GPR19,GUCY1A2,KPNA5,KITLG,MOBP,ZNF862,NOS1,MINDY2,RPS20,PREX2,SLC9A5,MAPKBP1,ZCCHC24,ZHX3,SYNE1,PCDHA5,DICER1,AP4E1,ZMYND8,VIPR2,VLDLR,ZNF45" Drug 1658_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NDRG2,AK2,AMPD3,CDC42BPA,CFAP410,CAMK2B,CAMK2G,ARHGEF1,SCARB1,CNOT8,ZFYVE9,HOMER3,SH2B1,DCAF4,EDRF1,DSCAM,DTNA,EXTL2,F3,OLFM1,DISC1,PCSK1N,SPACA9,GRIK5,PADI2,ACOT7,LSS,MEIS2,MIA2,SCAMP5,MMP16,PPP2R2B,UEVLD,FBXW7,WLS,FNDC3A,SMTN,ZHX3,SPART,CEP68,STX1A,PLCB1,ROBO3,TRIM2,TMOD1,RBFOX2,METTL3,TRPC1,TRPM2,VGF,WIPF1,XRCC4" Drug 7182_UP Strophanthidin [66-28-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADCY6,AK2,MRTFA,PPFIA3,ADAM15,BCL7A,CFLAR,BMP7,SYNJ2,RAB29,RAB28,RASSF2,JAKMIP2,LYPD1,TRAPPC9,DRD1,DSCAM,RCAN1,COQ7,F3,PRKAG2,SEMA4D,EFCAB2,DPYSL4,ZMYND11,COPS8,ELOVL5,HNMT,JAK2,KCNH2,KCNJ3,LIG4,RETREG1,MINDY2,PRODH,RIPOR1,RGS12,KCNIP1,SLC1A7,PPP4R3A,RBM34,EMC1,TROVE2,SS18,MAPK8IP3,ARC,PCDHA6,AHCYL2,AP4E1,ZBTB14,UBE3B,NUP214" Drug 4807_UP Nystatine [1400-61-9]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADCY6,ADORA1,BEGAIN,AMH,APOC1,MARK4,SLC2A11,CFAP410,CBFA2T2,CHRNB2,DAPK3,ATN1,EDN1,SIDT2,SORBS3,RASGRP2,F5,REEP2,DLC1,KAT8,KHDRBS3,GPR153,GRIN1,KCNJ5,KCNMA1,LSS,MDM4,AFDN,PALM,PDE3B,RETREG1,PLTP,CDIP1,RALGDS,FBXW7,ZFP2,PPP1R9A,SLC6A8,SLC20A2,WDTC1,ST5,PHLDB1,SYT5,SMG6,RIMBP2,TRIO,UGT8,OSBP2,WIPF1,MKRN3,NT5M,JPH3" Drug 3016_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "APC,ASCL1,ADGRB3,BMP7,BTRC,CFAP410,RUNX1T1,RAB26,HOMER3,CSF1,SUSD5,CNTNAP2,CALY,SPOCK2,RUSC2,KLHL3,SV2B,HS3ST2,DRP2,EFNA3,EFNB3,SRPK3,REEP2,ADAMTS8,RASSF8,MBNL1,CD200,P2RY13,PCSK5,GDAP1L1,PPP2R2B,BCAS3,PTHLH,PTH1R,RAD52,RASGRF1,PRR5L,EMID1,SLC11A1,SOX15,NFASC,TACR1,TRIM2,PHF24,ATP13A2,DNAH7,TGFBR3,TMOD1,SSBP2,KLC2,PMEPA1,GAN" Drug 3837_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "DPF1,ABR,ASIC1,NME5,ADGRF5,SEMA7A,PLA2G4C,CDK13,STOML1,PICK1,COL9A3,NCOR2,CNTNAP2,EDRF1,DAPK3,RUSC2,SGSM2,EIF4G1,TNK2,CALCRL,ERCC2,DLC1,FGF13,CAMSAP1,C1orf61,RUNDC3A,GSN,DHX35,KCNH2,KHK,LSS,MMP17,NEUROD1,NUMA1,SNTG1,PRKCB,RYR1,ZNF331,RASA3,BCAN,SON,HECW1,IQSEC2,ATP11A,KAZN,TBCEL,WSCD1,TRIO,FLRT2,VAV2,SPHK2,AP3B2" Drug 4683_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "KIDINS220,AGT,APBB2,GAS7,ADAM23,CACNA1G,LDLRAD4,CAST,SYNGR3,PLEKHB1,NRXN3,RAB26,SH2B1,CNTNAP2,DZIP3,ARHGAP24,CTIF,DPH1,ATN1,DTNA,EFNA3,ETV1,ANKMY1,C1orf61,AFF2,SORBS1,FYB1,B4GALNT1,ERAP1,INPP5K,GPER1,CNTRL,RASSF8,NDP,NF1,NFIX,OPCML,PDE4D,PRKAR1B,PRPH,RGS10,ROM1,FOXRED2,SUPT20H,PPP4R3A,IZUMO4,ARHGAP26,PHLDB1,ASTN2,TK2,FAM13C,KAT6A" Drug 4321_UP Ethoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ASPHD1,KIDINS220,CADM3,FUBP1,CACNA1I,RUNX1T1,CRLF1,ARHGAP22,TBC1D5,MAML1,PHYHIP,CTIF,AK5,DTNA,MAMLD1,EDN1,HIPK3,EPB41L2,ZNF549,C1orf61,CSPG5,B4GALNT1,SYT17,PRUNE2,GPR17,ITGA7,ITPKA,LAMA2,SMAD1,TAGLN3,NHLH1,NPR2,NPTX2,OPRL1,TNPO2,PRKAR1B,RASGRF1,RGS4,RGS12,RNASE1,EMID1,FAM214B,SLC11A1,SLCO1A2,ZC3H13,IQSEC2,DMXL2,GPR161,ICAM5,SEZ6L,NDRG4,MVB12B" Drug 2317_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABR,ALCAM,MRTFA,BIN1,APC,APOC1,CDK13,MARK4,CDK5R1,SCAPER,CBFA2T2,HOMER3,FAM169A,PPP6R2,MFAP3L,DNM1,TOM1,SORBS3,COQ7,NCALD,F3,PRELID3A,GPR153,SEPT9,INPP5K,POLL,GRIK5,NR3C1,GRM1,GSN,KCNH2,KCNN2,NFYA,NOS1,OGDH,PCDH9,MINDY2,RAD52,RGS10,SLC1A7,BTBD7,KIF13A,UNC5B,CAMTA2,TTBK2,PHLDB1,STX1A,SYN2,KIAA1107,CRTC1,BHLHB9,KAT6A" Drug 4468_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ATM,KIF1A,BACH1,RAB28,EDRF1,DCT,SPOCK3,CDON,DTNB,EDN1,EBI3,EPHB1,KCNMB2,REEP2,FYB1,RND1,RAB30,PRUNE2,NXPH3,HTR2A,ICA1,LIFR,MMP16,MX1,NTRK3,ODF2,OMG,OPCML,PDGFRA,MTRF1L,PPP2R2B,CEP41,SAMD9,PTAFR,PTPRH,PTPRN2,TCP11L1,SYNDIG1,SEMA6D,NTNG1,SLC6A11,SLC11A1,ARHGAP26,INKA2,SZT2,DOCK9,TEX15,SLC44A1,TK2,ICAM5,TPM3,SLC17A7" Drug 5084_UP Resveratrol [501-36-0]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADCY6,KCNAB2,GAS7,RASL11B,MYRF,MAP7,CHN2,ARHGAP22,CLCN4,DNAJB5,COL9A2,AKAP5,CRY2,ABCG1,CSF1,PDE4DIP,RUSC2,EDNRA,SIDT2,FGF1,ADAM28,GLRB,GPER1,TPPP,ICA1,SHISAL1,MAPT,MMP17,MYO7A,PDGFRA,SERPINI1,RETREG1,PLCD1,SPATA6,TNPO2,PTPRH,PTPRN2,TMEM231,RPS6KA2,AMBRA1,ARHGEF40,SAMSN1,MAPK8IP3,TIMP4,R3HDM1,TNS1,CADM1,VAV2,NDRG4,SPHK2,WNK1,GAN" Drug 7520_DN Ald1.1-H_000455; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "MTUS1,PPFIA1,APAF1,PPP4R4,SCAPER,CBFA2T2,MAGI1,TAOK2,NRXN3,DNAJB5,CNTFR,NCOR1,PDE4DIP,SPOCK2,DNAJC6,SMG7,EXOG,SIDT2,EGFR,TUBD1,ANKFY1,PDLIM5,OGA,COPS8,GLYR1,GLS,GNG4,KPNA5,MBD1,MIA2,NF1,NUMA1,OPRL1,PLXNB1,LRP12,MAPK9,PTPRN2,PID1,RGS10,PPP4R3A,FAM214B,KDM4D,ELMO2,DOP1A,PLCB1,ARHGEF12,DICER1,AP4E1,SSBP2,ZKSCAN5,ZBTB14,MVB12B" Drug 5073_DN Loracarbef [121961-22-6]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "RALGAPA1,ARID1A,ADCY6,AP2A2,APC,APOC1,BCL2L2,BTRC,FOXN3,SOCS6,B4GALT6,TPP1,AKAP7,BAG4,CSF1R,VCAN,ARHGAP24,SMG7,KBTBD11,ATN1,EFNA3,LRRC23,SEMA4D,C1QL1,GLRB,IFI16,MX1,ZNF862,NDP,CLDN11,PLCD1,MAPK7,CNNM2,PTPN13,PTPRE,FAT4,TRAPPC13,MAPK12,SCN8A,SH3BP2,FUZ,COA1,BEX1,SPTAN1,VAMP1,ZNF34,TNS1,CADM1,WNT7A,FIP1L1,KAT6A,PHTF2" Drug 4548_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AP2A2,MTUS1,NME5,APBB2,MARK4,ASPH,CHN2,NRXN3,SLC4A8,CREB5,AATK,CNTNAP2,FBXL5,EDNRA,PLXNC1,TENM1,MRNIP,COQ7,SPEG,KCNMB4,TDRKH,GRM1,KLF12,SYNPO,IL6R,MAP4,TM6SF1,MEIS1,MIA2,SCAMP5,MX1,CNOT4,FAT4,RGS4,RGS10,MYH14,ZNF821,AMBRA1,SLC20A2,SPTAN1,DDN,MAPK8IP3,TIAM1,CABIN1,TNS1,SMUG1,LMF1,LAT2,NSD2,NDRG4,SYNC,EMSY" Drug 3298_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "KIDINS220,AMPD3,CDC42BPA,SEMA7A,CNTNAP1,APC,ATM,CFLAR,CACNA1I,CACNG1,HAP1,SCARB1,CLGN,FOXN3,SLIT2,SULT4A1,CNTN1,RIMS3,LYPD1,ATN1,ELN,DLC1,FOXG1,OGA,HPGDS,ADAMTS13,GRM1,GRM8,IL6R,KCNQ3,NDUFA5,PDE4B,PLCB2,PLCD1,LRP12,MINDY2,CEP41,PTPRN2,ASAP3,ARHGEF40,SLC9A5,SNCA,WDTC1,ST5,INKA2,JMJD6,KIAA1107,HEY1,CA14,VAV2,DNALI1,ITM2C" Drug 3726_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AP2A2,ALK,APOC1,APP,CDK10,C5,CACNA2D2,PICK1,SDC3,CTNND2,PARD6A,AK5,DMPK,DTNA,SIDT2,CELSR3,EIF4G2,ING4,ELAVL3,MRNIP,EZH1,SCML2,FGFR1,HBS1L,GRIK2,CACFD1,KPNA5,TM6SF1,MDM4,MT1M,TAGLN3,NELL2,NF1,NPR2,PDE4B,PTCH1,PLPPR1,FAM120C,ZCWPW1,RGS4,ZNF821,DOCK10,ZHX3,MAPK8IP3,MLC1,ATP11A,TIAM1,ZMYND8,VGF,VIPR2,NT5M,TIGD6" Drug 5679_DN Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "APC,EPB41L5,ARRB1,ARRB2,ADAM15,BCL7A,CFLAR,BTRC,SCARB1,SRSF11,ZFYVE9,CLOCK,CSNK1E,SIPA1L1,ZNF804A,MFAP3L,RCAN1,FEM1B,FECH,FGFR1,PRELID3A,TRAF3IP2,MALT1,GLYR1,MSL3,HNMT,HSD17B1,ICA1,MAPT,MATK,MDM4,LYRM9,CNOT4,SERPINE2,PLXNB1,PTPA,PRPH,RAD51D,RALGDS,RAP1GAP,WLS,FBXO11,EPN2,SHANK2,ZBTB43,MAPK8IP3,TACC1,TCF7,TMOD1,TPM1,HIRA,LMF1" Drug 4165_DN Trimethadione [127-48-0]; Down 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADORA1,SPARCL1,AMPD3,GAS7,MARK4,SEPT7,SLC4A7,CRMP1,SNCAIP,CSF1R,RASSF2,GIT2,DBN1,PLXNC1,DMTN,ERCC2,FHL1,AFF2,SEPT9,RND1,GSN,TJAP1,VWA5A,MAP4,KITLG,ADAM22,NLE1,MTRF1L,LRP12,PRKCB,PTHLH,C1orf54,TRIM68,ZFHX4,ZNF821,SH3BP2,PPP1R9A,RPH3A,SLC9A5,ZCCHC24,VPS13A,PLCB1,ROBO3,EXOC7,RPGRIP1L,PSD3,HEY2,TRPM2,ZMYND8,FAM155A,PLSCR4,EPM2A" Drug 5301_UP Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "NME5,OGT,KCNAB2,APOC1,PPFIA3,ARNTL,ASPH,ALDH4A1,ATM,STX16,ATP6V0A1,ARHGAP33,EPS15L1,VAX2,EDRF1,DCAF8,ZNF337,GIT2,JAKMIP2,FCF1,EFNA3,EPB41L2,F3,EFCAB2,TXNL4A,GLYR1,BTN2A1,KHK,ADAM22,NASP,NDUFA5,NFYA,LRP12,PPP2R5C,LRRC49,RAD51D,RGS12,ITSN1,SYBU,ZNF430,RCOR3,CLASP2,GANAB,ARHGEF9,TBL1X,SATB2,TCF7,TPM1,METTL3,ZNF24,WNK1,NAV2" Drug 2529_UP Nadide [53-84-9]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,ARID1A,BIN1,APAF1,CAPRIN2,ASPH,BMP7,CACNA2D1,CD86,B4GALT6,SIPA1L1,DZIP3,ZFYVE16,RIMS3,SV2B,ENO2,EPB41,ERBB2,AGAP2,ZMYND11,NEU3,GCNT2,GFER,GPD2,KIF3A,AP4S1,HRH3,LSS,KCNK10,PDE4A,DUSP26,CCSER2,PPP5C,RTN1,SEC14L1,SCG5,SH3BP2,EPN2,TMCC1,SOX10,SPTAN1,SPART,ACSBG1,VAMP1,KIAA1107,TBCEL,AHCYL2,TMOD1,TNNT1,TRO,KLC2,SENP7" Drug 2306_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ADCY6,APBA2,ARSE,DNAH17,CFLAR,GYG2,CALB2,CAST,CDO1,JAM2,AKAP6,NTM,HEYL,ELAVL3,ELN,RCAN2,KCNMB2,SPEG,FGF14,FHL1,SORBS1,TPK1,GAB1,NEU3,ADAMTS8,IL6ST,KCND3,KIF5A,KPNA5,MID1,ADAM22,CDIP1,PTCH1,RGS12,ZFHX4,RYR1,SALL1,SHANK2,SLC14A1,SP4,ZBTB43,SPART,INKA2,KAZN,GPR161,THBS4,RUNDC3B,OSBP2,VIPR2,ZIC3,SLC30A3,STMN4" Drug 4124_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ASIC2,ALCAM,MRTFA,AMPD3,GAS7,DNAH17,CACNG1,CAMK2B,HIP1R,ARHGEF1,FADS2,CNTFR,WHRN,SH2B1,NCOR2,AATK,VCAN,RIMS2,DCT,DMPK,CDON,SGK2,SRPK3,DMTN,NRN1,DLC1,GABRA2,GFAP,GRM1,GSTM5,PTGDR2,ATXN2L,MYT1,PDE1C,RETREG1,MAPK7,PTH1R,ZSCAN2,KHDRBS2,CRTAC1,SCN8A,STUM,SLC1A2,ARHGAP26,POGZ,AJAP1,KIAA1107,HIF3A,TK2,PIK3R5,TRIO,WNK1" Drug 1639_UP 2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ASPHD1,ABHD6,NDRG3,SRPX,ST3GAL5,GYG2,RAB29,ZFYVE9,PLAA,WHRN,EDRF1,SMG7,RCAN1,RBM12,EFNB3,EGFR,F3,FYN,COPS8,GLS,POLL,KCNMB4,GNG4,GRIK5,DIPK1A,MPP2,ZNF862,PALM,PC,PDPK1,PIK3CD,RETREG1,PACSIN1,PRPH,PTCH1,RAD51D,CARF,NEK11,PPM1E,TSNAXIP1,ZBTB43,KAZN,AP4E1,BEX4,ZKSCAN5,VAV1,VGF,MICAL1,REEP1,MAP3K12,HPS4,SMIM8" Drug 6357_DN Condelphine [7633-69-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "BIN1,EP400,APLP1,APOC1,CDC42,CLU,FADS2,WHRN,HDAC9,GIT2,CNIH3,DLG3,CNNM1,MRNIP,GPHN,EZH1,TRAF3IP2,DENND2A,ARFIP1,GNG4,GPER1,KIF5C,L1CAM,MAP4,MT1M,ZNF862,NAP1L1,NUCB1,OPCML,PC,NLE1,PRPH,RAB3IL1,RAD51D,BSDC1,TRAPPC13,ASAP3,FUZ,PEX26,CDK5RAP2,WDTC1,DDN,CAMTA2,POGZ,MAPK8IP3,GSE1,ARHGEF9,SYN2,WWC1,SCG2,MPPE1,TIGD6" Drug 3294_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "AP2A2,PLA2G4C,ST3GAL5,ARHGEF7,WHRN,CREM,ARHGEF10,NOS1AP,MFAP3L,TRAPPC9,MBNL2,ELAVL2,LRRC17,MTSS1L,FOXG1,TRAF3IP2,SEPT9,ADAM28,GLS,NR3C1,BTN2A1,GSTM5,ATXN2L,HNMT,ITIH2,MDM4,BCO1,N6AMT1,PCDH8,CDK14,CDIP1,STRN3,POLG,MAPK7,PEX5,RNASE1,SH3BP2,ASAP3,DOCK10,PEX26,SLC9A5,ZKSCAN3,WDTC1,SOX2,AJAP1,POPDC3,KIAA1107,SYNE1,KCTD2,CADM1,KCNK12,SPHK2" Drug 4169_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "SYN3,ADORA1,CDC14B,ARSE,LDLRAD4,CACNG1,CALB1,KALRN,CAMK2B,CHN2,CLCN4,STOML1,CREB5,ARHGEF10,DAPK1,DRP2,DTNA,DTNB,ST8SIA3,SNX29,EDN1,C3orf18,EFS,SPEG,FHL1,TBR1,OGA,SIGLEC8,GFER,RUNDC3A,PRDM5,GRM8,GUCY1A2,IL6R,LMO1,MEF2C,AFF1,MX1,TREM2,ELOVL2,NKAIN1,SLC11A1,TSNAXIP1,PEG10,COLGALT2,PHLDB1,ATP11A,TNS1,CHST5,VGF,WIPF1,AP3B2" Drug 4749_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "ABHD6,ADRA1D,NME5,LTBP4,MRTFA,FAM131A,CDC14B,ZBTB10,EIF4G3,BCL7A,CFAP410,CAMK2G,TAOK2,FAM189A2,CREM,ARHGEF4,PPP6R2,SLC12A6,EFNB3,DLC1,C1orf61,AFF2,DPYSL4,NR3C1,ATXN2L,IL6ST,MDM4,MEF2C,KITLG,NF1,NFYA,CNOT4,NUMA1,RETREG1,LRP12,SAMD9,FAM120C,RGS3,FERMT1,LIMCH1,ZNF423,SPTAN1,CDK19,TTBK2,STX1A,ARC,ROBO3,TNS2,SLC44A1,TMOD1,ZNF74,EVI5" Drug 3331_UP Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-05 1.00E+00 7.87E-04 8.95E-03 52 196 "KIDINS220,NME5,APBA2,APLP1,BRINP2,RASL11B,SLC4A4,N4BP2L1,BAIAP3,CFAP410,CRLF1,ZFYVE9,PICK1,RIMS3,GSDME,TMCC2,DRD1,ELAVL3,MTSS1L,ERCC2,SPEG,AGAP2,KHDRBS3,GABRA4,HBS1L,GNAO1,LILRA2,RAPGEF1,GRIK5,GRM8,TJAP1,ITGAM,MMP17,CD200,FXYD7,NF1,NOVA2,PDE4B,PACSIN1,POU3F4,MED1,SAMD9,PEX5,ZDHHC14,ST6GAL1,LIMCH1,KDM4B,MAPK8IP3,AJAP1,SYT11,CRTC1,VIPR2" Drug CID000000190 adenine Stitch 7.00E-05 1.00E+00 7.95E-04 9.05E-03 113 510 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,NME5,AK2,AMPD2,AMPD3,DPP10,APAF1,APC,NT5C3B,APP,ALDH7A1,BCS1L,BLM,LDHD,CACNA1E,P2RX6,AIFM1,CD38,ENTPD2,CRY2,GDA,CS,NOS1AP,CYBB,AK5,SLC29A4,FCF1,LPAR6,ERCC2,GMPR2,FCGRT,MAD2L2,POLK,AK8,AHCYL1,ZNF274,MTHFD2,GART,GCK,NFU1,GK,TXNL4A,GLS,GPM6A,LPAR4,RFFL,HPS5,IDH3A,IDH3B,MAP4,MAT2A,MSRA,N6AMT1,DDX25,P2RY13,NCF2,NFIA,NFIX,NME4,OGDH,OGG1,P2RX7,P2RY1,PAH,PDE2A,PKM,SLC25A23,PMP2,TRHDE,PMS2,POLG,PSMA6,PYGM,QDPR,SLC25A41,REV3L,RNASE1,NUDT11,RYR1,RYR3,SHMT2,SIRT2,SNCA,SPATA7,NMNAT2,SPP1,ADHFE1,ABCC8,NUDT10,TBL1X,SMG6,TCF7,NSD1,AHCYL2,CYB561A3,SIRT1,RBFOX2,TPM3,SMUG1,NEIL2,HSPBP1,P2RY12,PRTFDC1,MSRB3" Drug CID005353676 hydroxystilbamidine Stitch 7.20E-05 1.00E+00 8.18E-04 9.31E-03 32 103 "ACHE,CALB1,CALB2,RGN,SULT4A1,CNTFR,DTNA,ELAVL3,PPP1R1B,GAD1,GAD2,GFAP,GFRA1,STMN2,GRIA1,GRIA4,GRIK1,GRIK5,KCNC2,NEFM,NPY,NTRK3,OPA1,PENK,SLC6A1,SST,SYP,TAC1,TACR1,SCG2,SLC17A7,SLC17A6" Drug CID000028683 4 alpha-phorbol Stitch 7.20E-05 1.00E+00 8.18E-04 9.31E-03 32 103 "ASIC1,CACNA1B,CACNA1E,CACNA2D1,CALM1,CHRM1,CLCN3,SH2B1,EDN1,PNMA2,GAP43,HNF4G,MYLK2,KCNA2,KCNA4,KCNJ3,KCNJ5,KCNK3,MX1,NPR2,MBOAT7,PTPA,PRKCB,PRKCG,PSMA6,SMTN,PLCB1,SYT1,SYNE1,TPM3,SPHK2,PLD4" Drug CID003036508 Pc 12 Stitch 7.31E-05 1.00E+00 8.30E-04 9.45E-03 55 211 "ADCY6,ADORA1,ADORA2A,ADORA3,APLP1,APP,ASCL1,NGB,AIFM1,LRBA,CHGA,CHGB,CHRNA4,CHRNB2,NRG2,NCAN,GPSM1,RCAN1,RGS17,ERBB4,PTK2B,PPP1R1B,FGF1,SMC2,ATP2C1,PCSK1N,GNAO1,GRIA2,CPT1C,MAOB,NPY,NTRK3,PCSK1,PIK3CD,PRKACB,PRKCB,PRKCG,MAPK3,MAPK8,MAPK9,MAPK10,PRPH,QDPR,RAP1GAP,RAP1GDS1,SLC8A2,SNAP25,SYN2,SYP,SYT1,CNTN2,TK2,TMPO,SLC30A3,SCG2" Drug CID000002533 calphostin C Stitch 7.47E-05 1.00E+00 8.48E-04 9.65E-03 98 431 "ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,AGT,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,LRBA,CHN1,CHRM1,MYL6B,TJP2,PICK1,DBI,EDN1,EDN3,EDNRA,EDNRB,RASGRP1,EGFR,ERBB4,PTK2B,ACTL6B,CAMKK2,ATP2C1,MSTN,GRIK2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,HTR2A,MYLK2,IGF1,SCIN,ITGAV,KCNJ3,ASPRV1,MBP,MYH6,MYL3,NODAL,NOS1,NPPA,PDYN,ABCB1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKM,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,PTH1R,PTK2,MAPK12,SMPD3,FNDC3A,SLC8A2,SLC8A3,SLC11A1,PEG10,ITPRID2,MLC1,PLCB1,SYT1,LEFTY2,ACTR6,CABIN1,NEIL2,PLPPR5,PLD4,GOPC,CAMK1G" Drug 2856_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.63E-05 1.00E+00 8.66E-04 9.85E-03 50 187 "RALGAPA1,APBA2,ATM,CFLAR,CACNA1I,LDLRAD4,CA12,KYAT1,ZFYVE9,ARHGEF6,GREB1,SPOCK2,DBT,TSPAN5,EGR3,ANKMY1,FAM49B,INPP1,INPP5B,JAK2,KCNF1,KCNH2,LMO2,MAN2A2,MID1,AFDN,NF1,GPR85,C19orf57,MAPK8,ELOVL2,RAD52,C1orf54,RET,RGS12,EMID1,SGK1,SH3BP2,SYBU,PEX26,SLN,COA1,SNCA,SOX3,DMXL2,ZKSCAN5,REEP1,PRDM2,ITM2C,TIGD6" Drug 7536_UP 0393-0188; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "KIDINS220,ZBTB10,SCAPER,MYRF,SOCS6,LHX2,PLAA,HOMER3,SLC4A8,CRY2,HINFP,SLITRK5,TMCC2,EDIL3,CELSR3,EIF5,EN2,F3,FYB1,B4GALNT1,POLL,HSD17B1,SCIN,DIPK1A,KCNJ5,KCNN1,CNOT4,CLDN11,PDGFRA,MED1,PTN,RAB3IL1,FAT4,KCTD17,ROM1,RPS6KA2,CLIP1,FAM214B,SMARCD3,SOX10,ELOVL4,TTBK2,SYT1,TNS1,TRIO,RUNDC3B,HIRA,FAM155A,PRDM2,EPM2A,RNF146" Drug 7538_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "SEMA4G,ADGRB2,CDK5R1,MYRF,MAP7,USP2,WHRN,CREM,AKAP12,CRY2,CSNK1E,CTH,SGSM2,ATN1,DTNA,EFNA3,PLEKHO1,POLR1B,CGREF1,ZMYND11,B4GALNT1,POLL,ATXN2L,SHISAL1,CNOT4,NLE1,PLCD1,SMOX,MED1,CNNM2,PTHLH,PTN,RAB3IL1,TCP11L1,FAM214B,SMARCD3,ARHGAP26,SPTAN1,PBLD,ELOVL4,TTBK2,WWC1,CRTC1,AHCYL2,TNFRSF1B,TNS1,TPM2,ZMYND8,FAM155A,LMF1,FIP1L1" Drug 5930_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "ASPHD1,ANK3,GAS7,CDK13,SCAPER,CACNA1I,IL33,CACNA1A,CACNA2D1,CACNA2D2,DNAJB5,ARMC8,ABI3BP,VCAN,PDE4DIP,SLITRK5,PARD6A,DMPK,MBNL2,LRRC23,ETV1,F3,FOXG1,SEPT9,GNG4,GPR17,LPAR4,RASSF8,KLF12,HNMT,IL6ST,ADAM22,NDP,NUMA1,PDGFRA,PTPRN2,ASAP3,DOCK10,SLA,SHANK2,SPTB,LHPP,MAPK8IP3,TIAM1,TIMP4,RBFOX2,ZKSCAN5,WNT7A,ZBTB38,NAV3,SLC17A7" Drug 7195_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "DNAH17,MARK4,ASPH,SLC2A11,ADAM23,CFLAR,CDK5R1,SCAPER,SLIT2,QKI,HOMER3,CREM,CTIF,GIT2,DBT,HP1BP3,RUSC2,LYPD1,RCAN1,EFNA3,EGR3,MALT1,MSL3,NR3C1,IRF8,JAK2,KCNN1,KITLG,SERPINE2,RETREG1,STRN3,PRODH,SAMD9,ROBO1,LGR4,SLC1A7,BTBD7,SLC22A4,ZKSCAN3,TTC17,WDTC1,EMC1,SS18,MAPK8IP3,KAZN,KIAA0930,TMPO,SSBP2,XRCC4,MAP3K12,MPPE1" Drug 3041_UP Luteolin [491-70-3]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "CDK5R1,LDLRAD4,CD86,CDH10,DLGAP1,CREM,AATK,RGS6,ATRNL1,PDE4DIP,CTNND1,RIMS2,GPRASP1,INTS1,KLHL3,EDIL3,EGR3,EFS,KAT8,HBS1L,GAP43,ZNF276,GRIN1,KCND1,KCND3,KCNJ5,SMAD9,MEF2C,MYH3,OMG,OXTR,SMIM7,PRPH,KCTD17,RPS20,PAQR6,SCG5,SLC11A1,SOX10,CLSTN2,STX1A,TAC3,TACR1,PCDHGB6,ATP13A2,TF,FLRT1,PMEPA1,PRDM2,SLC17A7,PCBP4" Drug 1337_UP Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "ABAT,NDRG2,APP,MYRF,CFAP410,CAMK2G,CCNT1,CHN2,CLCN4,ENTPD4,CSF1R,PDE4DIP,USP6NL,RUSC2,RABGAP1L,PHC2,NCALD,CELF1,RAB40B,GNAS,PADI2,MAP4,MATK,ZNF862,NEK1,NUMA1,OGG1,SERPINE2,ST8SIA5,SMIM7,PEX5,RXRA,SEC14L1,ITSN1,FUZ,FAM214B,MAPKBP1,PALLD,ZBTB43,ARHGEF9,EXOC7,CAMSAP2,TK2,ICAM5,KCTD2,TNS1,TST,ZFP37,GDPD5,ST7,NLRP3" Drug 7155_DN Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "NME5,APBB2,APP,SLC4A4,CFLAR,SCAPER,CAMK2G,SLC25A14,CLCN4,ARHGAP32,FEM1B,SORBS3,IRAK4,VPS13B,COQ7,F3,ATP8A1,ZNF589,KIAA1109,ANKFY1,DLL3,INPP5K,SRCAP,COPS8,POLL,GPD2,KIF3A,ITPKB,LIG4,NF1,NFYA,SLC11A2,ODF2,PLCD1,RC3H2,KLK6,SNRK,SUGCT,ATXN2,AMBRA1,LIMCH1,WDTC1,ARHGAP26,COLGALT2,ARHGEF9,KIAA0930,TNS2,ZNF34,TRPC1,SMIM8,RNF146" Drug 7485_UP Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "AP2A2,SYT13,ALDH4A1,SLC4A4,SLC2A11,MTMR3,USP2,FADS2,CREM,MICAL2,SDC3,JAKMIP2,SPOCK3,SGSM2,TMCC2,DSCAM,RCAN1,SUGP2,ERCC2,FECH,DISC1,GLS,GNG3,ATXN2L,ITIH2,KCNH2,IPO5,MAPT,PPP2R2B,CNNM2,VPS13C,PTAFR,PTN,RAB3IL1,RPS6KA2,SEC14L1,SH3BP2,SLC1A7,SLC6A9,SNCA,ZHX3,TROVE2,SYN2,TAC3,SEMA4A,TRIM2,PCDHA6,MICAL1,TFIP11,UPF3A,SEMA3B" Drug 2081_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "ASIC1,ADD1,APOC1,APP,MADD,SCAPER,OSGIN2,LHX2,AKAP7,PDE4DIP,SDC3,GPRASP1,EGFR,ABI2,LPAR6,TUBD1,F3,CINP,FAM49B,DISC1,SRCAP,COPS8,GNAS,SLC2A6,MUM1,INPP5B,IPO5,MPP2,SETD4,OGG1,PC,PDE4A,POLG,MAPK3,BSDC1,RGS10,SH3BP2,SCMH1,BTBD7,SPTAN1,ELOVL4,ARHGEF9,EXOC7,TCF4,ZEB1,TSN,LMF1,ZBTB14,TFIP11,PHTF2,AAAS" Drug 2831_UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "MTUS1,NME5,AMPD3,APC,ATM,CFLAR,CAMK2B,USP2,CDH18,QKI,SLC4A7,NCOR2,ARHGEF4,NOS1AP,DCAF8,MAGI2,EXOG,SHANK1,EDNRA,MBNL2,ANKMY1,BAIAP2,SCARA3,ZNF44,DISC1,GNG4,LPAR4,NR3C1,MAOB,MYO7A,ZNF862,PDE3B,PMS2,MINDY2,PTHLH,ZNF493,ZFHX4,EMID1,PDZRN3,SOX3,SOX10,IQSEC2,CLSTN2,POGZ,AJAP1,WSCD1,AP4E1,DAAM2,SPHK2,EVI5,ST7" Drug 5118_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.82E-05 1.00E+00 8.85E-04 1.01E-02 51 192 "KIDINS220,AMPD3,BRINP2,CACNG1,CALB2,CAPN3,BRSK2,LHX2,CSF1,CTH,HDAC9,RUSC2,DTNA,TOM1,EPB41,EFS,KIAA1109,OLFM1,SORBS1,SIGLEC8,GLI2,LPAR4,SPACA9,ELOVL5,BRINP3,KCNA2,VWA5A,ADAM11,ADAM22,PTPRN2,PTX3,ZSCAN2,C1orf54,RGS4,RGS10,RASA3,SLA,SLC4A3,KANSL3,SLC6A9,SNAP25,MAPK8IP3,ACSBG1,SYT1,TK2,VIPR2,LAT2,TFIP11,CAMK1G,NLRP3,JPH3" Drug ctd:D014403 Tubocurarine CTD 7.87E-05 1.00E+00 8.87E-04 1.01E-02 24 69 "ACHE,SLITRK1,CAPRIN2,CHRNA4,CHRNB2,KMT2C,CNTN1,FEZ1,ATRNL1,CD99L2,DSCAM,EDIL3,EML4,LRRTM3,KCNN1,KCNN2,LSAMP,PENK,MAPK3,RELN,RBBP6,SPP1,TAC1,UBE3A" Drug CID006437089 PbTx-1 Stitch 7.92E-05 1.00E+00 8.87E-04 1.01E-02 13 27 "ASIC1,ASIC3,PTK2B,GABBR1,GJB1,KCNA2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,JMJD6" Drug 3303_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "NME5,MRTFA,ADAM23,ST3GAL5,USP2,CBFA2T2,RAB33A,CLCN4,STOML1,SULT4A1,AKAP7,BAG4,RIMS3,SPOCK2,JAKMIP2,EDNRB,EGFR,ELAVL2,F5,ZNF589,CAMSAP1,FOXG1,GLS,GRM3,GRM8,GSTM5,ICA1,ITIH2,KIFC3,NOVA2,OMG,OPCML,TREM2,PLTP,CEP41,BSDC1,RYR1,ASAP3,SNCA,KDM4B,WDTC1,SOX10,ZNF423,ZC3H13,ARHGEF12,PCDHA6,TF,SLC30A3,NT5M,DNALI1,EVI5,KCNAB1" Drug 2218_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "KIDINS220,MRTFA,APC,EPB41L5,PPFIA3,PLA2G4C,MARK4,SLC4A4,ATP6V0A1,KIF1A,MTMR3,CAMK2B,CDH10,CLGN,FOXN3,DNAJB5,AKAP7,ARMC8,ENTPD4,ABCG1,SDC3,RIMS3,ZNF804A,DNM1,COQ7,SCML2,FHL1,FAM49B,PRELID3A,CSPG5,GNG4,GPER1,SPACA9,GSTM5,ATXN2L,IL6ST,NUMA1,PRKAR1B,TMEM104,PTHLH,RAB3A,RGS10,SEC14L1,IQSEC2,ROBO3,TBL1X,TNS2,TMEM121,THRA,ZIC3,WNK1,PRDM2" Drug 6928_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,PPFIA3,AQP6,ARHGDIG,ATP2A2,ALDH7A1,SGCE,CACNA1I,USP2,TMEM257,CLU,FAM149A,NRG2,FEZ1,FAM169A,HDAC4,LYPD1,CDON,EDNRA,EGR3,ABCA8,ACSL4,EFEMP1,ATP8A1,FGFR1,SEMA4D,DPYSL4,GABRA2,GLI2,IL6ST,MAG,NNAT,NOVA2,NUMA1,PDE4A,RETREG1,NLE1,MED1,PPP2R2B,PTN,EMID1,RYR1,FRMPD1,TSNAXIP1,KDM4C,CLSTN2,PLCB1,IQCE,DOCK9,CDK20,KCNK12,HPS4" Drug 2204_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BIN1,KCNAB2,BCAS1,BMP7,C5,SLC16A4,CBFA2T2,CDC42,ZFYVE9,PLAA,RAB26,ABCG1,VCAN,PDE4DIP,EDRF1,CTIF,SMG7,SV2B,EXOG,TRAPPC9,SGK2,SORBS3,ELN,VPS13B,NCALD,PDLIM5,RND1,PCSK1N,MBP,MEF2C,NUCB1,OPRL1,SLC25A23,TNPO2,POU6F1,PRKAR1B,PRPH,PTPRN2,RAD52,ZNF365,SNCA,PALLD,ST5,TEX15,ATP13A2,CHST8,FLRT2,XRCC4,PRDM10,HPS4,SLC17A7,NLRP3" Drug 5751_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ADCY2,SLC12A5,AP2A2,APBB2,APC,GAS7,ARHGDIG,ATP6V0A1,INA,CLCN4,CLTB,COL9A3,NCOR2,ABCG1,CTNND2,NOS1AP,RIMS3,C2CD2L,ABCC9,HIPK3,SEMA3D,FGF1,ALDH1L1,SRCAP,GFRA1,COPS8,GLYR1,GRK4,SPACA9,KLF12,ELOVL5,KHK,KIT,LSS,DDX25,NF1,NRCAM,PDE4D,GPR85,PPP5C,PTN,ACSS3,TMEM206,SPTB,LHPP,TROVE2,POGZ,TBCEL,SEZ6L,VAV1,SLC13A3,ZIC3" Drug 208_DN SC-58125; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,ADORA1,OSBPL1A,APBB2,PPFIA3,CDK10,BCL7A,KYAT1,TAOK2,CLTB,PCYT1B,CHD1L,PPP6R2,DCAF8,DCT,C2CD2L,DYNC1I1,ATN1,DSCAM,FEM1B,EFNA3,EFNB3,ING4,EPB41L1,PIPOX,NCKAP1,GRIK5,PRDM5,ARHGAP19,ICA1,KCNN1,MITF,MMP16,SNX10,PTAFR,CCDC25,ASIC4,SFPQ,SH3BP2,URGCP,SLC11A1,ERC1,ZC3H13,RAP1GAP2,CEP68,TBL1X,WSCD1,HEY1,KAT6B,SEZ6L,METTL3,UBE3A" Drug 5999_DN (1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SLC12A5,KIDINS220,CDC42BPA,PKP4,BCAS1,PDE8B,NUMB,SYNJ2,MTMR3,CBFA2T2,ARHGEF2,ZFYVE9,HOMER3,HINFP,FEZ1,GIT2,MFAP3L,RABGAP1L,EFNA3,LRRC23,ANKMY1,KAT8,KIAA1109,CINP,ATP2C1,SEPT9,MALT1,MSL3,GRM1,ITPKB,KHK,MAP4,ZNF862,NEK1,NUMA1,LRP12,TMEM231,CCDC25,TRAPPC13,KIF16B,ZNF365,ZHX3,TTBK2,PLCB1,PCDHA5,TMEM121,TPM1,TRPC1,HIRA,WNK1,GDPD5,KAT6A" Drug 3132_DN THIP Hydrochloride; Down 200; 22.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BIN1,APBB2,APC,BTRC,SCARB1,IQCK,CREM,DGKG,SPOCK2,SMG7,ECM2,ERCC2,PTK2B,FHL1,NBEA,CSPG5,GAA,SEPT9,GLYR1,POLL,GRM1,TJAP1,IL6ST,KIT,MAP4,N6AMT1,NINJ2,NPR2,OXTR,PDE4D,SLC25A23,CNNM2,ZSCAN32,PID1,RPS6KA2,RASA3,CPEB3,FBXO11,MYH15,TMCC1,ZCCHC24,ARHGAP26,RAP1GAP2,NCDN,EXOC7,CAMSAP2,TCF7L2,KCTD2,FLRT1,CLIP2,ZNF225,NT5M" Drug 3870_DN (S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,BIN1,CDC42BPA,APC,APOC1,APP,MARK4,CACNB2,CRLF1,DNAJB5,NCOR2,RIMS2,USP6NL,CTIF,DMPK,DSCAM,PLXNC1,HSD17B14,COQ7,ZNF589,SCARA3,C1orf61,FYN,GCNT2,SRCAP,RND1,GLS,ITPKB,NUMA1,PLCD1,SLC25A23,FSD1,MAPK8,PTHLH,PEX5,CCDC40,RAD52,RGS10,KCTD17,RXRA,ZKSCAN3,WDTC1,IQSEC2,MAPK8IP3,TTBK2,RGL1,TCF7,TRIM2,HEY1,ZIC3,SYNC,ITM2C" Drug 1693_UP Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BRAP,AK2,MRTFA,DOC2A,TRMT9B,APC,APLP1,APOC1,SEMA4G,MARK4,FOXN3,SLC4A7,SPOCK2,RCAN1,TSPAN5,EIF4G2,HSD17B14,ENO2,DLC1,FGFR1,FHL1,IQCG,HBS1L,GRIN1,ICA1,KCNQ3,MAPT,MGAT3,NF1,NFYA,NNAT,PCDH9,NLE1,MBOAT7,PACSIN1,ATG16L1,RGS10,SUPT20H,SLC15A2,KIF13A,KDM4C,ST5,PLCB1,TBL1X,TCF7L2,CHST8,PIK3R5,VGF,VIPR2,LAT2,PRDM2,PHTF2" Drug 6665_UP Famotidine [76824-35-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SPARCL1,BMPR1B,BAIAP3,KALRN,HAP1,CAMK2A,BRSK2,CBFA2T2,CDH10,CHGA,FAM149A,CSF1,ARHGEF10,INTS1,DAPK3,DCT,C2CD2L,HIPK3,EFNB3,MTSS1L,APC2,OLFM1,ZNF44,SIGLEC8,CSDC2,GLI2,GNAL,SPACA9,GRM1,GRM7,HSD17B1,KCND3,KCNJ5,KITLG,ADAM22,NCAM1,ENPP2,PENK,PFKFB2,PFKFB4,RETREG1,PMP2,POU6F1,LRRN3,MAPK8,KIRREL1,HECW1,TIMP4,TPM2,ZNF74,SLC30A4,JPH3" Drug 5771_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "RALGAPA1,KIDINS220,TRMT9B,RASL11B,ADAM23,CACNA1I,BTRC,NGB,CBFA2T2,ARHGAP22,HOMER3,CABP1,ENTPD4,SH2B1,CRMP1,NCOR2,ABCG1,DCC,DMPK,MBNL2,EN2,FYB1,DENND2A,GFER,HPGDS,POLL,GPM6A,GRIK5,CACFD1,ATXN2L,HTR5A,KCNJ9,VWA5A,MMP16,CD200,NOVA2,SLC11A2,PDE3B,EPN1,PLP1,POLG,DCHS2,C1orf54,ASAP3,SLCO1A2,ZHX3,ABCC8,DICER1,CRB1,TK2,TMOD1,SLC17A7" Drug 3722_DN Tropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,ALK,APBB2,CDC14B,ALDH7A1,BTRC,CACNA1A,AP4M1,LARGE1,B4GALT6,QKI,AKAP7,SLC4A7,NRG2,CPS1,VCAN,SPOCK3,AK5,ATN1,DTNA,HIPK3,EIF4G2,COQ7,ETV1,ZNF589,OGA,DISC1,ARFIP1,INPP5B,JAK2,CNOT4,ODF2,PC,PCDH9,PIK3R1,MAPK8,PTCH1,FNDC3A,PPP4R3A,KDM4B,SS18,NXT2,SYT11,TEX15,TMPO,RBFOX2,TRIO,VLDLR,NSD2,ZNF24,SEMA3B,SENP7" Drug 2389_UP Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "APAF1,SEMA4G,PRX,INA,RAB33A,DNAJB5,ABCG1,CNIH3,GSDME,EXOG,EDNRA,EFNA3,PLEKHA1,DMTN,FOXG1,CAP2,INPP5K,RUNDC3A,PCSK1N,MCHR1,WIF1,ICA1,MMP16,MOBP,ZNF862,NELL2,NF1,NPTX2,KCNK10,PDGFRA,CAMKV,POU3F4,FSD1,PPARA,MAPK8,RELN,PTPRN2,GAL3ST4,DOCK10,SLC1A7,KDM4B,IQSEC2,ARHGEF9,DNMBP,KIAA1107,PSD3,ARHGEF12,ATP13A2,CHST8,ZNF34,KCTD2,SSBP2" Drug 7009_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,ARID1A,MRTFA,PLA2G4C,SLC4A4,CADM3,ADAM23,SYNJ2,GYG2,KYAT1,TAOK2,NCOR1,HDAC4,MFAP3L,DMPK,CELSR3,SORBS3,ING4,FAM198B,PRELID3A,PCDH17,RAB30,GPR75,ADAMTS13,KCNJ3,MAN2A2,MAP4,MBD1,SETD4,PLCD1,PLTP,POLG,PPARA,PRKAR1B,GRAMD1C,RGS10,GSTCD,SLC1A7,RBM34,TSNAXIP1,CLASP2,INKA2,PLCB1,ROBO3,TMOD1,PIK3R5,WBP2,XRCC4,ZBTB14,NDRG4,MAP3K12,ITM2C" Drug 7277_UP Azapropazone [13539-59-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "LGR5,WASF1,MAP7,ZFYVE9,HOMER3,NRG2,SLITRK5,FAM131B,ARMCX2,RUSC2,RGS17,RABEPK,ETV1,FGF13,BAIAP2,FLNC,TRMO,COPS8,MUM1,IL6ST,SCAMP5,MKLN1,PALM,PBX1,PDE1C,PLCD1,ZNF426,CDIP1,FA2H,PRKAB2,MAPK7,PTHLH,PTPRN2,RAD52,KHDRBS2,RGS4,SFPQ,SLC14A1,CAND2,SPTAN1,ZBTB43,SPART,THSD1,WWC1,ZEB1,PARD3,RUNDC3B,SSBP2,WNT7A,NDRG4,KCNAB1,PHTF2" Drug 4024_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "EPB41L5,CDC14B,ADGRB1,CFLAR,HAP1,CCK,CDC42,CHM,JAM2,IFFO1,CSNK1E,CTNND2,EDRF1,SEC14L5,PHYHIP,HIPK3,EFNB3,EGFR,EPHA5,ETV1,KIAA1109,OLFM1,PRELID3A,GAB1,ERAP1,SIGLEC8,GPM6B,GRM7,PACRG,MATN3,TM6SF1,MMP16,NEFM,NPY,ARID4A,BEND5,RBBP6,GAL3ST4,GSTCD,MRAS,LIMCH1,CRTC1,R3HDM1,TNS1,TPM1,CHST5,CADM1,VGF,VIPR2,ZNF24,KCNAB1,DPF3" Drug 1707_UP Acetohexamide [968-81-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "DOC2A,AMT,APC,PLA2G4C,MARCH3,SLC4A4,SLC2A11,BTRC,B4GALT6,RAB28,ZFYVE9,CREM,NCOR1,TBC1D5,GIT2,SMG7,RCAN1,CNNM1,EGFR,ANKMY1,ZNF589,TMEM8B,GHR,MALT1,GLYR1,SLC2A6,ELOVL5,ZNF862,CNOT4,NPTX1,SETD4,PDE3B,PRKAR1B,PRPH,GSTCD,ZNF331,SUPT20H,PREX2,PPP4R3A,SLC22A4,WDTC1,ZCCHC24,KDM4C,PLCB1,TRIM2,TPM1,ZKSCAN5,VIPR2,LMF1,SLC30A3,GJC2,SSPN" Drug 438_DN copper(II) sulfate pentahydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BRAP,APBA2,DGKD,NCOA1,LHX2,STOML1,TMEM59L,AATK,ARHGEF10,DZIP3,ECE2,C2CD2L,KLHL3,EXOG,HIPK3,EFNB3,MBNL2,RASGRP2,CDKL3,CEND1,GAB1,TMEM8B,MALT1,BTN2A1,RNFT2,KCND3,KCNF1,MMP16,NOS1,NPR2,OPCML,PDE1C,PLCD1,POLG,MAPK8,PRODH,MASP1,PTPRN,RIPOR1,TCP11L1,ST6GAL1,SLA,SLC1A2,SLC11A1,ELMO2,EMC1,TAL1,TNS1,SEZ6L,ZIC1,MPPE1,NUP214" Drug 2975_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,AMPD3,CASK,CAPRIN2,ASPH,SLC4A4,ATP6V0A1,BCL2L2,RCBTB2,PDE4DIP,PPP6R2,EGR3,ANKMY1,F8,FHL1,FLT1,ZNF44,INPP5K,SRCAP,ADAM28,TXNL4A,GOLGB1,GPR19,LPAR4,DIDO1,CACFD1,GSN,ZNF862,RETREG1,PLEC,PMP22,STRN3,PTPA,MAPK3,GON4L,RIPOR1,RPS6KA2,ATXN7,SH3BP2,FBXO11,SLC6A8,KDM4B,ZCCHC24,EMC1,ZKSCAN5,FLRT2,BCL2L13,ATP6V0E2,REEP1,PRDM2,WIPF2,SENP7" Drug 5262_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ADCY6,SPARCL1,BRINP2,ADAM23,SYNJ2,CAMK2B,CDH10,CACNA2D2,NCOR2,ARHGEF10,DNAJC6,TMCC2,DMPK,DTNA,DTNB,SIDT2,ELAVL3,VPS13B,EFS,PTK2B,KIAA1109,C1orf61,HBS1L,DISC1,ALDH1L1,GLYR1,POLL,STON1,GRM1,SHISAL1,TJAP1,MYT1,PDE1C,RAB3A,CARF,SYNDIG1,ASAP3,CPEB3,SLC2A5,HECW1,RBM26,MAPK8IP3,SYT11,POPDC3,ROBO3,EXOC7,ZEB1,TRIM2,PARD3,CHST5,FAM155A,PARP11" Drug 6947_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SLC12A5,AP2A2,SEMA6A,MARK4,ASTN1,CFLAR,BAIAP3,CACNA1D,CALB2,DLGAP1,PLEKHB1,NMT2,STOML1,ARHGEF6,CREM,NCOR2,CTNND2,EDRF1,LRRC23,CAMSAP1,DPYSL4,GPR153,ALDH1L1,TOX3,CACFD1,ELOVL5,INPP1,MPP2,MSI1,BCO1,SLC11A2,NUMA1,PLEC,MTRF1L,GON4L,WDR25,SLC1A7,SLC6A9,MAPKBP1,KDM4B,KIF21B,SS18,MAPK8IP3,ASTN2,KAZN,WSCD1,AHCYL2,TMOD1,LMF1,SPHK2,EMSY,NAV2" Drug 438_UP copper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ACTN1,GRAMD1B,KIAA1324,SYT13,APC,SLC4A4,CADM3,ATP6V0A1,SYNJ2,CACNA1I,CHN2,CHRNB2,TAOK2,DAPK3,DRP2,ABCC9,SEZ6L2,HIPK3,SORBS3,IRAK4,PDLIM5,ZNF276,LUZP2,GRIK5,SOX21,LAMP2,PTOV1,NRDC,PC,NLE1,PLEC,MBOAT7,PPP5C,MAPK3,RLBP1,RNASE1,SYNDIG1,SH3BP2,ITSN1,SHANK2,CLASP2,FCHO1,ZFR2,TRIM2,TRPC1,TRPM2,DNAJC12,WNT7A,ZNF24,TFIP11,ACTR3B,AAAS" Drug 3473_DN Iopamidol [60166-93-0]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,NDRG2,BIN1,CDC42BPA,APBB2,CDK13,CFAP410,NMT2,IQCK,ABI3BP,CRY2,CSNK1E,MFAP3L,DTNA,SIDT2,ZNF589,B4GALNT1,DISC1,GCNT2,POLL,LPAR4,CACFD1,ATXN2L,HNMT,HSD17B1,IGSF1,LSS,MBD1,GIT1,NEK1,MAPK3,ELOVL2,ZSCAN32,RIPOR1,AMBRA1,ABLIM3,MAPKBP1,RBM34,ASTN2,SEMA4A,IQCE,TCF7L2,TNS2,TMOD1,KCTD2,KAT6B,TPM1,CDK20,UBTF,MAP3K12,ZNF248,RNF170" Drug 7546_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ACTN1,AP2A2,CDK10,MARCH3,ATP2B2,ARHGEF2,PLEKHB1,SULT4A1,HOMER3,DCAF4,KIAA0513,DNAJC6,PARD6A,SPOCK3,AK5,DNM2,EFNA3,EGFR,RGS17,CGREF1,SIGLEC8,INPP5K,GLYR1,STON1,PTGDR2,IL12A,KIF5C,NF1,KCNK10,PIK3CD,CNTLN,RAP1GAP,RGS3,MYH14,CCDC25,RPS6KA2,ZFP30,SH3BP2,AMBRA1,ARHGEF9,ZEB1,ARHGEF12,TPM2,RUNDC3B,UGT8,ZNF711,ZNF74,UPF3A,NAV3,MVB12B,EPM2A,ACTR3B" Drug 7199_UP Ketotifen fumarate [34580-14-8]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "APC,CASK,ADAM15,CFLAR,KSR1,CDK5R1,LHX2,QKI,SLC4A8,PDE4DIP,FAM169A,CTNND2,EDRF1,GPRASP1,LYPD1,PARD6A,RCAN1,EDNRA,MBNL2,COQ7,RRAGB,F8,ACSL4,KAT8,KIAA1109,AGAP2,EFCAB2,DPYSL4,GCNT2,GLYR1,KCNJ3,KCNMA1,LIG4,MDM4,PRPH,WDR25,ZFP30,PPP4R3A,RBM34,HECW1,SPTAN1,CLASP2,NXT2,SEMA4A,KIAA0930,TRIM2,AHCYL2,DICER1,TMOD1,PLPPR2,VIPR2,CLDND1" Drug 2376_DN Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "NDRG2,ALK,MRTFA,ANK2,APC,CDK10,ARNTL,NCOA1,ATM,N4BP2L1,CCNT1,EPS15L1,IQCK,CST3,FBXL5,KIAA0753,SIDT2,COQ7,RASGRP2,ANKMY1,FGFR1,OGA,HBS1L,SEPT9,ALDH1L1,COPS8,MSL3,JAK2,LIG4,MAP4,GIT1,CNOT4,NRGN,P2RX7,PIK3R1,RAB3A,CEP97,RALGDS,RET,TCP11L1,ARFGAP1,ZKSCAN3,ZBTB43,SRPK2,SEPT8,NSD1,TLR4,PIK3R5,RBFOX2,ZNF74,ST7,NLRP3" Drug 3335_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ADORA2A,MRTFA,KCNAB2,APLP1,OSGIN2,CA4,CA12,MAP7,CLU,FAM189A2,FADS2,CREM,CRY2,FAM169A,USP6NL,TBC1D5,MAML1,ARMCX2,SGSM2,RABGAP1L,EFNA3,SORBS3,EIF5,STX2,SEMA4D,PDLIM5,GALC,SEPT9,GRB10,ICA1,INPP5B,ITPKB,IPO5,MAP4,NUMA1,SLC25A23,PRKAR1B,ZNF821,SMTN,SHANK2,EMC1,IQSEC2,PLCB1,SEMA4A,SMG6,TCF7,TCF7L2,AHCYL2,TRPC1,VIPR2,EVI5,HPS4" Drug 3769_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,AMPH,AQP4,PDE8B,ATP1A3,MTMR3,CACNA1D,KALRN,CDH8,SLC22A6,EPS15L1,SULT4A1,AATK,SUSD5,ERC2,FRMPD4,ATN1,DTNA,ST8SIA3,RASGRP2,OLFM1,PDLIM5,ALDH1L1,SRCAP,POLL,GNAL,GRIK5,ICA1,ITIH2,KIFC3,TAGLN3,NUMA1,TREM2,CDK18,PIK3R1,NECAB2,PAQR6,SCNN1D,CNKSR2,SOX2,NPAS3,ATP10B,MCF2L,TAL1,CRTC1,TLR4,RIMBP2,SEZ6L,TRPC3,TUBB1,ZIC3,ZNF225" Drug 2762_UP Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "DPF1,KIAA1324,PLA2G6,BEGAIN,SEMA7A,APC,AQP4,SEMA4G,ST3GAL5,LDLRAD4,CA4,NMT2,WHRN,SH2B1,TENM4,RASSF2,DNAH9,DUSP9,EDNRA,PLXNC1,FHL1,IQGAP2,PCDH17,GPER1,GRM1,GRM7,IL6R,KCNB1,KCNH2,MAP4,TAGLN3,MX1,NEUROD1,NNAT,MASP1,PTX3,C1orf54,ZNF493,ZDHHC14,RGS12,STUM,SH3BP2,PKNOX2,CXXC4,PEG10,SEMA4A,PSD3,DICER1,LAT2,XRCC4,PRDM2,HRASLS" Drug 3026_UP Ioversol [87771-40-2]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,SLC12A5,SEMA6A,ALK,DDO,APOC1,CDC14B,DDX3Y,CCDC181,ATP1A3,RGS9,SOCS6,CHI3L2,ZNF337,DGKB,TMCC2,HEYL,SRPK3,ELN,EPB41,KAT8,PRELID3A,B3GAT1,GABRA5,ALDH1L1,GFER,ZNF276,GLI2,IL6ST,KCNC1,KCND3,KCNJ3,LAMA2,MMP16,DDX25,NFIX,POU6F1,PTH1R,MYH14,KCNIP2,SEMA6D,IL17RB,UNC5B,ARHGAP26,ROBO3,TCF7L2,PHF24,CRB1,TIAM1,SEZ6L,LMF1,KCNAB1" Drug 7477_DN Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AK2,ALAD,CDC42BPA,MARCH3,ALDH4A1,B4GALT6,STOML1,HOMER3,CSNK1E,SOCS5,PDE4DIP,PPP6R2,DCAF8,KIAA0586,GIT2,C2CD2L,DSCAM,EFNA3,CGREF1,SEPT9,GRB10,NR3C1,PADI2,ATXN2L,HNMT,MITF,N6AMT1,SETD4,PRKAR1B,SIDT1,NKAIN1,RAD51D,RALGDS,CCDC25,PEX26,ZKSCAN3,ZBTB43,FAM168A,TACC1,TRIM2,KCTD2,NPL,TRPC1,ZMYND8,VGF,VIPR2,LMF1,NDRG4,EMSY,GDPD5,ST7,UBE3B" Drug 2513_UP Delsoline [509-18-2]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BCAR3,CDC42BPA,CDC14B,SEMA4G,ASPH,CADM3,BACH1,CACNA1A,CALB1,HAP1,CDH2,ABCG2,FAM149A,CELSR3,EGFR,ING4,KCNMB2,ERBB2,CDKL3,DLC1,FGFR3,GAB1,GFRA1,LYVE1,GLS,GNAL,GRM1,KCND3,MID1,MOBP,NTRK3,OLR1,PCDH9,PRKAR1B,PROX1,SUSD4,SCN2B,SCG5,NLGN1,SLCO1A2,SORCS3,THSD1,MAPK8IP3,KAZN,CAMSAP2,TK2,ICAM5,SEZ6L,KCNK12,SCG2,PHTF2,SENP7" Drug 3212_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "PLA2G6,CDC14B,RGS20,ATM,CFLAR,USP2,TAOK2,ENTPD4,DAPK3,DNM1,DSCAM,SIDT2,SORBS3,COQ7,SEMA4D,DPYSL4,OGA,SEPT9,GRB10,ELOVL5,HNMT,TJAP1,INPP5B,KCNH2,MAP4,MATK,TM6SF1,MITF,MPP2,NPR2,PCDH9,PLEC,PLTP,RGS12,ZNF365,SCMH1,ZKSCAN3,RBM34,WDTC1,SOX3,ZBTB43,THSD1,NCDN,PLCB1,TCF7,ZNF34,TK2,ZMYND8,HIRA,PLPPR2,VIPR2,NDRG4" Drug 3572_DN Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "MRTFA,GAS7,APOC1,PPFIA3,MARK4,ATM,CFLAR,CACNB2,CRLF1,AKAP7,SLC4A7,SLC4A8,ABI3BP,EDRF1,DBT,C2CD2L,KBTBD11,DSCAM,EDNRA,EGFR,ING4,STX2,ANKMY1,INPP5K,USP19,CNTRL,ICA1,MATK,MITF,MPP2,ADAM22,MBOAT7,POLG,RAB3IL1,PAQR6,FUZ,PPP4R3A,SLC6A8,CCDC88A,SCMH1,BTBD7,MAPKBP1,ZHX3,EMC1,POGZ,IQCE,SMG6,TMEM121,AP4E1,ZMYND8,XRCC4,UPF3A" Drug 1406_DN Norfloxacin [70458-96-7]; Down 200; 12.6uM; HL60; HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AK2,APAF1,APBB2,ATP6V0A1,CD38,CDC27,TAOK2,EPS15L1,FEZ2,TM9SF4,SMG7,G3BP2,RCAN1,FEM1B,EFNB3,CEND1,TRMO,POMT1,LILRA2,GRB10,CACFD1,SCAMP5,MPP2,MYO5A,NEFH,NF1,NFYA,SLC11A2,PIK3CD,TNPO2,PTPA,CNNM2,C12orf49,ATXN2,SGK1,CCDC88A,SMARCC2,ARHGAP26,TAB2,MAPK8IP3,DIP2A,NSFL1C,ATP11A,TBL1X,DICER1,SPX,PIK3R5,RBFOX2,UBE3A,ZNF24,HPS4,URM1" Drug 6402_UP 3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASCL1,PDE8B,BRINP2,AZGP1,CACNA1G,EPS15L1,AKAP5,CSF1,ATRNL1,PDE4DIP,SEC14L5,SNPH,TMCC2,HIPK3,FCF1,C3orf18,NCALD,EFS,PIPOX,PTK2B,SORBS1,RND1,GNAS,GPM6A,ADAMTS13,KLF12,ICA1,KCNH2,MEF2C,MID1,ADAM22,MYO7A,NOVA2,OPCML,P2RX7,CAMKV,SLC25A23,PLTP,PTCH1,ZSCAN2,TCP11L1,SYNDIG1,KCNIP1,SLN,IZUMO4,NPAS3,ATP11A,TNS2,PCDHA3,TPM2,LAT2,PHTF2" Drug 6328_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BRAP,OGT,CFLAR,SPAG9,TAOK2,QKI,ARHGEF4,TM9SF4,GIT2,LYPD1,SMG7,DYNC1I1,AASS,TESK2,FGF13,CAMKK2,TXNL4A,GNG4,GPD2,GPM6B,DIPK1A,JAK2,MAN2A2,ZNF862,NUCB1,OCRL,CLDN11,PLCD1,RC3H2,MAPK9,ZSCAN32,PTPRN2,BEND5,RGS3,UEVLD,RPS6KA2,CSRNP3,SCG5,CDK19,TAB2,FBXW11,KIAA0930,TRIM2,ZNF34,TK2,PARD3,CABIN1,NAV3,MPPE1,ST7,ACTR3B,RNF146" Drug 2484_UP Terconazole [67915-31-5]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BEGAIN,ANK3,PKP4,PRX,PLA2G4C,ALDH4A1,ATP6V0A1,CDK5R2,BTRC,SCARB1,TAOK2,ZFYVE9,DAPK3,C3orf18,RASGRP2,ZNF549,CEND1,FGFR1,PDLIM5,CAMKK2,TMEM8B,RND1,GLI2,GLYR1,GPM6B,NCKAP1L,IL6ST,KCND1,MAP4,MPP2,MX1,NELL2,NINJ2,CNOT4,NTRK2,CCSER2,PTPN13,PEX5,SYNDIG1,ASAP3,LIMS2,RIMS1,SNCA,ARHGAP26,ATP10B,MAPK8IP3,SEPT8,WSCD1,TEK,TMOD1,AMACR,NAV2" Drug 2728_DN Butacaine [149-16-6]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SLC12A5,MTUS1,ANK3,APAF1,GAS7,ARRB1,NUMB,BACH1,FUBP1,MYRF,CHM,RAB33A,PPP1R16B,DTNA,E2F5,HIPK3,SIDT2,EIF1,F3,F5,PDLIM5,OGA,HTATSF1,GNG4,LILRA2,GRIK5,ITGAM,MEF2C,AFF1,AFDN,PLCB2,PMP22,PILRA,PPARA,PTCH1,TCP11L1,MRAS,SLC11A1,TROVE2,CRTC1,ICAM5,KCTD2,RBFOX2,TPM1,TPM3,TPM4,TRPS1,CLIP2,XRCC4,REEP1,WNK1,MAP3K12" Drug 6010_DN Triamterene [396-01-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,PLA2G6,ALCAM,AMT,APBA2,APC,ALDH7A1,SYNJ2,BTRC,SRSF11,ABI3BP,CSF1R,CNTNAP2,FAM169A,SDC3,RABGAP1L,KAT8,TRAF3IP2,GAD1,USP19,POLL,TDRKH,GRB10,IL6ST,KIF2A,MMP16,LYRM9,NDUFA5,NF1,PRPH,SAMD9,GON4L,PTN,FAM120C,CEP97,SEC14L1,MRAS,SH3BP2,BTBD7,CXXC4,SNCA,ZHX3,CLASP2,MCF2L,TK2,CDK20,ZFP37,REEP1,GDPD5,SEMA3B,KCNAB1,KAT6A" Drug 6077_DN Hexestrol [84-16-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BCAR3,BIN1,APBA2,APBB2,NCOA1,GYG2,PLEKHB1,ZFYVE9,VAX2,AKAP7,NECTIN3,CRY2,MICAL2,DAPK3,C2CD2L,VPS13B,EZH1,FAM198B,FOXG1,CINP,CGREF1,GHR,POLL,GPR37,HNMT,INPP5B,LMO2,LSS,KITLG,MMP16,GIT1,MSI1,NUMA1,PCDH9,PRKAR1B,SIDT1,PTN,ZSCAN32,GSTCD,WLS,SBF1,ITSN1,RBM34,KDM4C,ZBTB43,FAM168A,VPS13A,MTCL1,WBP2,ZKSCAN5,WIPF1,UBE3B" Drug 6952_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SEMA6A,APBB2,CFLAR,KSR1,ST3GAL5,SCARB1,LRRFIP1,AKAP7,PDE4DIP,GREB1,CTNND2,ARMCX2,SPOCK3,DMPK,OPTN,RBM12,SUGP2,EGR3,EFEMP1,FECH,FGF12,TJAP1,MIA2,NUMA1,PFKFB3,PLTP,SNRK,PTN,FAM120C,RGS10,MAPK12,FRMPD1,SLC6A9,KDM4B,ZCCHC24,ZHX3,ARHGAP26,SS18,MAPK8IP3,NSFL1C,ARHGEF9,ASTN2,KAZN,WSCD1,TRIM2,CRTC1,TK2,VGF,HPS4,SEMA3B,NAV2,PLSCR4" Drug 4955_UP Carisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,NDRG2,SPARCL1,LTBP4,MRTFA,AMH,APBA2,APC,MARK4,ASPH,ADAM23,AZGP1,GYG2,INA,HOMER3,CSF1,DUSP9,HIPK3,DMTN,PIPOX,KIAA1109,CAMSAP1,SEMA6C,SRCAP,PRUNE2,GPM6B,ICA1,ADAM22,NUCB1,OMG,PDE4B,PDPK1,RETREG1,CEP41,PRKAR1B,RAD52,ZFHX4,CARF,EMID1,SNCA,ZHX3,HECW1,IQSEC2,ARC,ATP11A,KIAA0930,PCDHA5,CABIN1,PLPPR2,ZBTB14,SEMA3B,EPM2A" Drug 3195_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "PLA2G6,MRTFA,TRMT9B,APC,PPFIA3,CDK10,ALDH4A1,ST3GAL5,MAGI1,TAOK2,QKI,CSF1R,ATRNL1,SDC3,CTH,ARHGEF4,PARD6A,EDNRA,FGFR1,CAMSAP1,ANKFY1,ZNF44,SRCAP,AHDC1,MALT1,POLL,LPAR4,NR3C1,INPP5B,LMO2,KITLG,MPP2,LYRM9,RAD52,EMID1,SBF1,FNDC3A,SLC1A7,WDTC1,SOX3,CLASP2,THSD1,ATP11A,SMG6,TRIM2,PCDHA5,ZNF34,TMOD1,CABIN1,TPM1,RUNDC3B,ZKSCAN5" Drug 1528_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ACTN2,ADORA2A,ADRA1D,ALK,AMPD3,KCNAB2,PPP4R4,MARK4,NCOA1,RASL11B,FGF17,RUNX1T1,ARHGEF1,ARHGAP33,CHRNB2,TAOK2,CNTN1,WHRN,NRG2,ENTPD4,MFAP3L,DSCAM,TOM1,ZNF589,FGF1,TDRKH,GSN,TJAP1,KCNJ4,MATK,MID1,ADAM22,NEK1,NEUROD1,PACSIN1,PTPRD,KCTD17,SEC14L1,DOCK10,SLC1A7,SLC6A9,SLN,RBM34,MYT1L,PEG10,STX1A,EXOC7,SZT2,TGFBR3,BHLHB9,PIK3R5,KAT6A" Drug 4787_DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "CDC42BPA,ANK3,PLA2G4C,RAB29,SLC4A7,CREM,AKAP12,LRIG1,MICAL2,PDE4DIP,SDC3,PPP6R2,HDAC4,DSCAM,EDNRA,ENO2,EZH1,F3,FECH,GAD1,TXNL4A,COPS8,MSL3,NR3C1,MAP4K5,HSD17B1,IL6R,SETD4,PDE3B,RETREG1,SMIM7,PPP3CC,TMEM231,RAB3A,RET,RGS10,SBF1,SLC22A4,ZHX3,SPTAN1,TTBK2,ARHGEF9,ATP11A,MCF2L,TIAM1,TSC1,ZKSCAN5,VGF,LMF1,XRCC4,REEP1,HPS4" Drug 6305_UP Nizatidine [76963-41-2]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,MTUS1,ALK,PKP4,PPFIA3,SHROOM2,PPP4R4,KIF1A,MAP7,NEURL1,TAOK2,DZIP3,PHF14,ARMCX2,DNAJC6,RABGAP1L,DMD,DSCAM,DTNA,EDIL3,MTSS1L,STX2,EXTL1,EZH1,HPCAL4,FLT1,USP19,KCNMB4,GPM6A,GRIK5,ITPKA,KPNA5,VWA5A,OCRL,POLG,LRRN3,SAMD9,ACSS3,MYH14,GSTCD,FBXW7,FRMPD1,NTNG1,SLC11A1,ZHX3,PCDHGA10,SLC19A3,CRTC1,TK2,NT5M,EVI5,KCNAB1" Drug 6792_DN Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,ATM,SYNJ2,SRSF11,SLIT2,ARMC8,ENTPD4,NCOR1,LRIG1,ARHGEF10,GIT2,DBT,DPYSL2,IRAK4,ERBB2,F3,FGFR1,ANKFY1,ATP2C1,ZNF44,SRCAP,AHDC1,TXNL4A,PADI2,INPP5B,MAPT,GIT1,SLC11A2,NUCB1,PCDH9,PLXNB1,TMEM231,ZCWPW1,GTDC1,ROBO1,CLIP1,ITSN1,KIF16B,NUBPL,SMTN,RAB3GAP1,PDZRN3,CDK19,CEP68,SYT1,ASTN2,OBSL1,KAT6B,RBFOX2,ZMYND8,NDRG4,NUP214" Drug 5397_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "DPF1,RALGAPA1,KIDINS220,AP2A2,SYT13,AMPD3,APP,CDC14B,ATP1A2,CADM3,ADAM23,CACNA1I,CACNA1A,CAMK2G,NEURL1,CHN2,CHRNB2,CNTFR,OSBPL3,RIPOR2,DRD1,EFNB3,PTK2B,PRELID3A,CHL1,ADAM28,GLYR1,PCLO,RASSF8,KLF12,TJAP1,KCNN1,SMAD1,NDUFA5,NELL2,NOS1,NPY,DDR2,PTCH1,TRIM68,SBF1,PEX26,FAM214B,SHANK2,SLC14A1,SMARCD3,RBM34,MCF2L,R3HDM1,TRIO,TRO,ZIC3" Drug 5106_UP "Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "TRMT9B,APC,RUNX1T1,ADGRG1,ENTPD4,CSF1,PYGO1,RUSC2,MAGI2,ATN1,PLXNC1,RASGRP2,NRN1,CORO2B,FAM49B,TBR1,FYN,GAP43,GRIK5,ADAMTS8,GSTM5,TJAP1,KIT,MAPT,MMP16,NDUFA5,NPR2,NPTX1,PCBP3,ENPP2,GPR85,MINDY2,MAPK7,SNRK,C1orf54,RGS12,TMEM206,RPS6KA2,IL17RB,SLA,ZNF667,SNCA,TMCC1,SPTB,DDN,SYT5,SMG6,TMEM121,TK2,AMACR,ZMYND8,SPHK2" Drug 2814_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BCAS1,APP,MARK4,ATP6V0A1,RIPK1,GYG2,BTRC,B4GALT6,FAM189A2,CNTN1,FBXL5,DMPK,DSCAM,DTNA,EFNA3,IRAK4,ING4,EZH1,FGFR1,IQCG,CGREF1,TRAF3IP2,TXNL4A,POLL,GNG4,ATXN2L,HNMT,INPP5B,JAK2,MAP4,MIA2,NEK1,NTRK2,MINDY2,PTPRE,TMEM231,RAD52,RGS3,SMTN,COA1,LIMCH1,MAPKBP1,ZCCHC24,SIN3B,DMXL2,RPGRIP1L,TMOD1,CDK20,TRPC1,PLPPR2,EMSY,FIP1L1" Drug 4557_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ACTN1,LGR5,CDH10,RAB28,NRXN3,DNAJB5,NRG2,SLITRK5,SDC3,TOX,KIAA0513,RHOBTB1,PLPPR4,EXOG,DTNA,EDNRA,PLXNC1,AASS,TENM1,PLEKHO1,DMTN,BAIAP2,PDLIM5,PRELID3A,GAD1,GBX2,MSL3,TDRKH,EML4,GRK4,GUCY1B1,MITF,NFYA,PDE1C,PLXNB1,PPP5C,PTN,PTX3,RAB3IL1,FAT4,IQSEC2,DDN,ASTN2,TNS2,TNS1,RUNDC3B,CADM1,OSBP2,WIPF1,HPS4,NAV3,MPPE1" Drug 5668_DN Dimethadione [695-53-4]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SLC12A5,EPB41L5,APP,ARRB1,ASPH,GYG2,BTRC,KYAT1,LHX2,VAX2,RCHY1,CSF1R,FAM169A,DCAF8,SPOCK2,MFAP3L,RUSC2,DTNA,SORBS3,ING4,EN2,STX2,PRELID3A,TBR1,OGA,SRCAP,GLYR1,GNAS,CNTRL,KCNF1,MITF,AFF1,ADAM22,FSD1,RAD52,BSDC1,CCDC25,SH3BP2,SLCO1A2,ZNF423,ZBTB43,SPART,CLSTN2,WSCD1,KIAA0930,PSD3,AMACR,PLPPR2,VAV1,VIPR2,EVI5,TIGD6" Drug 21_UP phenformin hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "RBM10,NDRG3,GAS7,ALDH4A1,RAB29,CAMK2B,CHN1,CHRM4,CLCN4,IFFO1,AATK,DBT,DCTN1,DNAJB6,OLFM1,BAIAP2,POMT1,GABRA4,AHDC1,ADAMTS13,HAPLN2,AGBL5,KCNJ5,KCNN1,L1CAM,MMP17,MYO6,NELL2,NOVA1,ODF2,PBX1,CDK18,PIK3CD,CCSER2,PLCD1,KLHL11,FAM192A,AMBRA1,PKNOX2,SON,ZCCHC24,ZC3H13,CLASP2,TBL1X,KCTD2,PARD3,CABIN1,SEZ6L,TRIO,PLPPR2,SLC13A3,VPS35L" Drug 5925_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,ACTN2,PLA2G6,AMPD3,APBB2,ATP2B2,ADGRB2,CFLAR,CACNA2D1,CAMK2B,INA,CBFA2T2,CLGN,ADGRG1,FOXN3,TPP1,CRYM,EDRF1,SNPH,RUSC2,DTNA,ANKMY1,TUBB4A,FER,FGFR1,FHL1,AGAP2,GAP43,ELOVL5,KCNMA1,LIFR,MID1,CD200,NOS1,PDE4D,PLEC,MBOAT7,PPP5C,WDR25,ZNF821,FNDC3A,CXXC4,LIMCH1,FAIM2,SS18,STX1A,TRIM2,DNAH7,HEY2,SLC17A7,MVB12B,DPF3" Drug 6402_DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,TRMT9B,APBA2,APP,ATP1A3,ADGRB2,KSR1,FUBP1,BTK,CACNA1A,CALB1,CDO1,CSF1,CSF1R,CNTNAP2,DAPK3,SPOCK3,ATN1,USH1C,CACNG3,KHDRBS3,GAD1,GAD2,DISC1,CSDC2,GLS,GPM6B,GRM2,KLF12,IFI16,IL11RA,KCNK2,KCNN1,VWA5A,MDM4,NF1,PLCD1,SPATA6,PACSIN1,MAPK8,RGS10,TMEM206,CCDC88A,SNCA,TAC3,KIAA1107,TCF4,SLC35G2,TRO,SLC17A7,ITM2C,MVB12B" Drug 2061_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,LTBP4,ANK3,APOC1,PDE8B,SLC4A4,NRP2,MYRF,PLEKHB1,CNOT8,DNAJB5,CSF1R,RIMS3,CTIF,DTNB,CNNM1,MTSS1L,KIAA1109,FGFR1,IQCG,PDLIM5,DLL3,TBR1,ZNF44,GFER,GLI2,GLYR1,STON1,CACFD1,PTGDR2,TJAP1,SCIN,ITGAM,MMP16,GIT1,NFIX,NNAT,DDR2,PC,NLE1,PLXNB1,WDR25,ELOVL2,RET,RGR,MYH14,ZFP30,IFT122,DDN,TRPC3,ZMYND8,DPF3" Drug 1641_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "NDRG3,SRPX,APLP1,ATP6V0A1,SCAPER,MTMR3,BTRC,CACNG1,MAP7,SRSF11,ZFYVE9,GPRASP1,KIAA0586,SPOCK2,CTIF,HP1BP3,RCAN1,KAT8,IQCG,FAM49B,OGA,GAD2,SRCAP,MSL3,LPAR4,NR3C1,DHX35,INPP5B,LSS,MDM4,MEIS2,KITLG,ADAM22,LRP12,ING3,PPP5C,MAPK8,RAD52,KCTD17,CCDC25,SHANK2,ZCCHC24,SPTB,SPART,TRIM2,CHST8,TRPC1,ZKSCAN5,VIPR2,URM1,MPPE1,UBE3B" Drug 2967_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "KCNAB2,SLC4A4,FUBP1,CA8,ARHGEF1,ENTPD6,NMT2,DNAJB5,CREM,CRMP1,GPRASP1,CTIF,DBT,SMG7,HIPK3,FCF1,TNK2,RASGRP2,ERCC2,KIAA1109,TPK1,KIF5C,LAMA2,AFDN,N6AMT1,SETD4,PDE4B,CCSER2,EPN1,CDIP1,POLG,CEP41,PTAFR,FAM120C,RALGDS,GALNT10,SLC15A2,SLC20A2,SNCA,RBM34,IQSEC2,SS18,EXOC7,PDLIM2,WWC1,TBL1X,EHBP1,ATP13A2,THRA,TK2,RBFOX2,UBTF" Drug 3233_UP Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,ASTN1,SYNJ1,LDLRAD4,CACNA1A,CACNA1D,RUNX1T1,FOXN3,AKAP5,BAG4,NOS1AP,RIMS3,CTIF,ZNF804A,SRGAP3,EFNA3,EGFR,PIPOX,PTK2B,OLFM1,FGFR1,HBS1L,GCNT2,SRCAP,GRM7,AP4S1,INPP1,ITGA7,ITIH2,KCNMA1,KCNN2,VWA5A,ZNF862,PDE3B,POU3F2,GDPD2,ZSCAN2,RAB3A,SBF1,SMTN,SLC6A8,SLN,ZNF415,ZCCHC24,ARHGAP26,MAPK8IP3,AJAP1,DOCK9,LILRA4,ITM2C,PHTF2,SSPN" Drug 5675_DN Colchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SLC12A5,APBB2,APOC1,APP,PDE8B,ALDH4A1,CFLAR,SCAPER,CA4,QKI,ARHGEF10,GPRASP1,MFAP3L,RUSC2,CELSR3,ING4,MRNIP,LRRC23,BAIAP2,PRELID3A,TBR1,TRAF3IP2,TXNL4A,GLYR1,HNMT,KCNJ3,MAP4,ZNF862,NF1,CNOT4,FSD1,PPP2R2B,MAPK8,LRRC49,SNRK,ZSCAN32,RAD51D,FOXRED2,SBF1,SHANK2,LIMCH1,ZHX3,THSD1,VAMP1,ATP11A,TGFBR3,FAM155A,VIPR2,MICAL1,EVI5,SCG2,TIGD6" Drug 2235_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "KIDINS220,AP2A2,APBB2,APC,ASPH,MTMR3,ARHGEF2,MAGI1,AKAP7,CSF1R,SIPA1L1,CTNND2,KIAA0586,MFAP3L,DSCAM,BAIAP2,CAMSAP1,FHL1,IQCG,HBS1L,GLYR1,POLL,CACFD1,GSTM5,IL6ST,INPP1,MYO7A,CDK18,PDE3B,PRODH,GON4L,RAB5B,RPS6KA2,ABLIM3,BTBD7,ZCCHC24,THSD1,ELOVL4,FAM168A,JMJD6,VPS13A,ARC,ROBO3,RPGRIP1L,PSD3,ARHGEF12,PCDHA6,ZNF34,ZIC3,SPHK2,KCNAB1,KAT6A" Drug 3270_DN Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "C1QTNF3,ALK,CDC42BPA,ANK3,APOC1,ATM,CA12,CACNA1D,CACNA2D2,SLC4A7,CSF1R,SDC3,GREB1,TBC1D5,SMG7,RABGAP1L,DSCAM,FHL1,OGA,NCKAP1,INPP5K,CNTRL,SPACA9,NR3C1,GSN,IL6ST,KPNA5,MBD1,MPP2,MSRA,SLC11A2,PCDH9,PIK3R1,PRKAR1B,FAM120C,RAD52,RGS12,GSTCD,EMID1,PAQR6,PPP1R9A,ANKRD6,PPP4R3A,EMC1,SPTAN1,IQSEC2,CDK19,KAZN,PSD3,CRTC1,KCNAB1,EPM2A" Drug 3042_DN Carbachol [51-83-2]; Down 200; 21.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ANK3,APBB2,HOMER3,ABI3BP,FEZ1,OSBPL3,VCAN,ZNF337,CTIF,KIAA0753,RHOBTB1,SV2A,EXOG,ABI2,PLXNC1,MRNIP,ST3GAL6,ATP2C1,GABRA4,SEPT9,INPP5K,WASF3,SPACA9,ELOVL5,KPNA5,NUMA1,ST8SIA5,SLC25A23,STRN3,LRP12,ZNF493,RET,RGS10,SEC14L1,MRAS,SH3BP2,CCDC88A,KBTBD4,BTBD7,CAMTA2,SS18,MAPK8IP3,CAMSAP2,DMXL2,ZEB1,TNS1,SMUG1,TRIM9,MKRN3,EVI5,UBE3B,PHTF2" Drug 6497_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SEMA6A,APOC1,RGS20,KSR1,CALB2,DLGAP1,CHGB,TPP1,HOMER3,NCOR2,ATRNL1,CNTNAP2,GREB1,MFAP3L,RCAN1,EFS,FER,FGF1,AGAP2,DLL3,PCDH17,GNAL,PRUNE2,RAPGEF4,GRM2,HAS2,ITIH2,KCNMA1,MATK,MBD1,MYO7A,CNOT4,GPR85,SAMD9,PTCH1,RAB3IL1,RGS3,RGS4,ZFHX4,ASAP3,MYH15,RIMS1,TRIM2,DOCK9,PSD3,DICER1,SLC44A1,SEZ6L,SPHK2,SLC30A3,KCNAB1,JPH3" Drug 2119_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "MTUS1,DOC2A,KCNAB2,APC,GAS7,PDE8B,ALDH4A1,BTRC,LHX2,COL9A3,CREB5,LRIG1,PDE4DIP,CNTNAP2,ARHGEF4,HIPK3,FCF1,EIF4G2,MTSS1L,ETV1,KIAA1109,FOXG1,POMT1,CINP,CGREF1,GAB1,SIGLEC8,GATM,POLL,GPM6B,KIF3A,GUCY1B1,KCNF1,KIF5C,PALM,PDE4A,PDE4D,PFKFB4,SUSD4,ZCWPW1,FNDC3A,BTBD7,SLN,TSNAXIP1,ZBTB43,PHLDB1,FBXW11,TCF7L2,TIAM1,USP1,ZNF24,TFIP11" Drug 5781_UP Spironolactone [52-01-7]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "DPF1,NDRG2,KLRC4,APAF1,CDK10,ARHGDIG,RGS20,ARSE,RASL11B,ATP6V0A1,ADAM23,BMP7,BTRC,ARHGAP33,LARGE1,CHRNB2,ARHGAP22,ZFYVE9,STOML1,ABCG1,SUSD5,EDNRB,HIPK3,CELSR3,MBNL2,COQ7,MTSS1L,NCALD,REEP2,FOXG1,SEMA4D,STMN2,GSTM5,MAN2A2,MMP17,TAGLN3,NELL2,PDE3B,MAPK8,RGS12,RIT2,CNKSR2,SNCA,TNIK,SOX10,HECW1,ZBTB43,KIAA1107,CHST5,VAV1,PRDM2,SLC17A7" Drug 2122_UP Nifenazone [2139-47-1]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ALK,BEGAIN,APP,SLC4A4,BRSK2,SCARB1,RAB28,DNAJB5,SLC4A8,SMG7,EN2,TUBB4A,INPP5K,C1QL1,KCNMB4,STMN2,CACFD1,GRM7,SOX21,PTGDR2,BACH2,SHISAL1,GIT1,NF1,CNOT4,PIK3R1,SPATA6,ELOVL2,PEX5,TMEM231,RAD52,RGS10,RGS12,KLHDC8A,RPH3A,ELMO2,WDTC1,SPTB,IQSEC2,LHPP,PHLDB1,TCF7L2,SYNE1,PSD3,VAV2,VGF,VLDLR,WIPF1,EMSY,PRDM2,STMN4,SCG2" Drug 2353_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "AP2A2,AMPD2,BIN1,RGS9,SYNJ2,CACNG1,GPR37L1,IQCK,SEC31B,CRMP1,ARHGEF4,SMG7,DNM1,RCAN1,SIDT2,COQ7,MTSS1L,ERBB2,SIGLEC8,SPIN1,KCNMB4,GNG3,GRM1,INPP5B,VWA5A,MAP4,MGAT3,NF1,NOS1,OGDH,SLC25A23,SYTL2,PTPRB,TMEM231,GAL3ST4,PNMA8A,SH3BP2,PKNOX2,SNCA,KDM4B,ZSWIM8,EMC1,DBNDD2,SPTAN1,PDLIM2,TBCEL,TBL1X,ARHGEF12,KAT6B,ZBTB38,SNX27,KAT6A" Drug 6788_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ABHD6,AP2A2,APBB2,ARRB1,PLA2G4C,NCOA1,SLC4A4,SCAPER,B4GALT6,SLC4A8,CRY2,ABCG1,ARHGEF10,SDC3,APPL1,CTH,GIT2,DMTF1,DSCAM,EDNRA,HIPK3,ING4,ANKMY1,FER,OGA,GLS,NR3C1,BTN2A1,ATXN2L,MAPT,ADAM22,NNAT,CNOT4,SLC11A2,PCDH9,PLXNB1,MINDY2,PPP2R2B,TMEM104,PEX5,NKAIN1,ZNF821,NUBPL,SMTN,BTBD7,ARHGAP26,ELOVL4,PHLDB1,ARC,TRPC1,MICAL1,SMIM8" Drug 3629_DN PNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "C1QTNF3,BIN1,ARHGDIG,PLA2G4C,NCOA1,CFLAR,SYNJ2,BTRC,SLC25A14,MAGI1,B4GALT6,BAG4,NECTIN3,DZIP3,EDRF1,MFAP3L,PARD6A,DTNA,EDNRA,SUGP2,MRNIP,RRAGB,FECH,FGF13,FGFR3,OGA,MALT1,MSL3,GNG4,ICA1,KCNN2,KITLG,MBOAT7,PTHLH,RAB3IL1,ZDHHC14,RGS3,ITSN1,SMTN,SLC15A2,DOK5,EMC1,KDM4C,THSD1,EXOC7,PCDHA5,AHCYL2,TPM1,TRIO,ZKSCAN5,FLRT2,VIPR2" Drug 3664_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SYN3,PTCH2,ALDH4A1,ATP1A3,ATP2B3,ATP6V0A1,BMP7,CACNA1I,CA12,HAP1,NEURL1,CHI3L2,COL9A2,COL9A3,AATK,CSF1R,FEZ1,RIMS3,DGKG,SHANK1,DRD1,ABCC9,EFS,OLFM1,BAIAP2,FHL1,FOXG1,GAB1,ALDH1L1,GFER,GPR17,GRM1,HTR2A,SMAD1,MMP17,NELL2,CNKSR2,DZIP1,SLC15A2,MYH15,ST5,AJAP1,SYT11,TACR1,PCDHGA10,TK2,CA14,UCHL1,SLC30A4,PARP6,SLC17A7,EPM2A" Drug 5317_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASPHD1,ABHD6,ARID1A,KIDINS220,APAF1,FAM131A,ASPH,ALDH4A1,ATM,ALDH7A1,KIF1A,ST3GAL5,CFAP410,CARS,FAM189A2,ENTPD4,CSF1R,PDE4DIP,CTH,CNNM1,EFNA3,EGFR,SORBS3,HSD17B14,ANKMY1,GALC,POLL,ICA1,LSS,MAP4,MAPT,MPP2,NFYA,PIK3CD,PPP2R2B,PRODH,CNNM2,LRRC49,PAQR6,ITSN1,EMC1,KDM4C,NXT2,PHLDB1,ZNF34,CABIN1,ZMYND8,VIPR2,MAP3K12,PRDM2,C12orf4,NUP214" Drug 5244_DN Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "BIN1,APOC1,DNAH17,SLC4A4,GYG2,CA12,CANX,SH2B1,ARHGEF4,NOS1AP,RASSF2,RABGAP1L,TSPAN5,EFNA3,MBNL2,SORBS3,MRNIP,NCALD,ZNF589,BAIAP2,PDLIM5,GPR153,RAB30,GLS,GNG3,ICA1,INPP1,KITLG,ADAM22,NUMA1,MBOAT7,TMEM104,RAB3A,RGS12,ZFHX4,SLC6A8,SLC9A5,LIMCH1,SNCA,ZHX3,ZC3H13,TROVE2,PHLDB1,KAZN,RPGRIP1L,CRTC1,TK2,PARD3,KAT6B,KLC2,MAP3K12,SEMA3B" Drug 2384_UP Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ADD2,CASK,ARRB1,ARRB2,ZSCAN18,KYAT1,CHRNB2,HOMER3,SLC4A7,RIPOR2,GSDME,MRNIP,RRAGB,FOXG1,PRELID3A,GABRA4,SIGLEC8,INPP5K,PCSK1N,GPD2,LILRA2,ICA1,IL11RA,ITGAM,MAPT,ZNF862,NPR2,PBX1,PDE1C,PDE4A,PDE4D,CCSER2,PLP1,MINDY2,PPP5C,MAPK8,MASP1,RASA3,KDM4B,KDM4C,SS18,STX1A,PDLIM2,PSD3,ZNF34,KCTD2,RBFOX2,SSBP2,REEP1,SYNC,MAP3K12,KCNAB1" Drug 3939_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "NDRG2,C1QTNF3,CDC14B,SEMA4G,CFLAR,ARHGAP33,PDE4DIP,DBN1,HIPK3,EFNB3,HSD17B14,DMTN,DLC1,ZNF589,FGFR3,GPR153,GAB1,GAD2,GCNT2,SRCAP,USP19,PCDH17,MSL3,GPD2,ADAMTS13,KPNA5,MAOB,MAP4,MSI1,MSR1,NF1,PDE1C,PFKFB2,MINDY2,CEP41,PRKCB,ZDHHC14,TCP11L1,RPS6KA2,EMID1,SEMA6D,SBF1,SELL,NLGN1,EPN2,LIMCH1,KDM4B,EMC1,ATP10B,RGL1,SYN2,PHTF2" Drug 4233_DN Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "PLA2G6,ANK3,APC,APOC1,CDK10,ARRB2,CDK13,ASPH,CAST,KIAA1549L,NMT2,CHD1L,CREM,ENTPD4,PDE4DIP,CNTNAP2,EDRF1,AK5,DTNA,PLXNC1,IRAK4,TUBD1,ETV1,ANKFY1,CINP,FYB1,GART,RUNDC3A,IL12A,ITGA7,KCNN1,MX1,CNOT4,NUMA1,PALM,PCDH9,PLCD1,RGS4,SUGCT,FUZ,FNDC3A,KANSL3,DOK5,SS18,RPGRIP1L,THRA,TIAM1,TMPO,XRCC4,ZNF711,SEMA3B,KCNAB1" Drug 5202_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ACTN2,C1QTNF3,ALK,SYT13,MARK4,CCDC181,GYG2,RUNX1T1,ASIC3,CHRNA4,ZFYVE9,CRY2,CSF1,SDC3,ZNF804A,RUSC2,NTM,DRD1,EIF4G2,LRRC23,CEND1,DLC1,FGFR1,GAD1,GNAO1,STON1,GPER1,SPACA9,GRIK5,GRM1,SLC2A6,MID1,MX1,ZNF862,NF1,NPPA,PCDH9,NECAB2,PTHLH,RAB3IL1,ZNF821,FAM214B,WDTC1,ZCCHC24,ARHGEF9,SYN2,EXOC7,ADGRL3,PCDHGA10,RUNDC3B,FLRT2,JPH3" Drug 5994_DN Lymecycline [992-21-2]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "SERPINA3,TRMT9B,CDC42BPA,APBA2,NCOA1,BCL7A,CFLAR,BTRC,KYAT1,RAB28,PLAA,ABI3BP,ENTPD4,SH2B1,CNTNAP2,IRAK4,MRNIP,STX2,FGFR1,BAIAP2,SEMA4D,GABRA2,GAD1,DISC1,INPP5K,MSL3,GPR37,GRM1,HNMT,ICA1,INPP5B,ITPKB,MAN2A2,MAP4,MMP16,MPP2,ZNF862,SAMD9,PTN,ZCWPW1,RGS3,RGS10,RNASEL,SH3BP2,ZNF365,EPN2,CXXC4,PLCB1,ATP11A,TCF7L2,NDRG4,EMSY" Drug 4500_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ASIC1,GRAMD1B,ALK,APBB1,SLC4A4,KIF1A,MPDZ,SCAPER,IL33,BTRC,RAB26,AKAP7,HAPLN1,CRY2,CSNK1E,ARHGAP32,TBC1D5,SGK2,RGS17,PLEKHO1,ANKMY1,KIAA1109,TMEM8B,SYT17,SEPT9,MSL3,POLL,GPER1,GUCY1B1,LSS,MAPT,ADAM22,TAGLN3,MX1,PLXNB1,MAPK8,GRAMD1C,PTHLH,RAB3A,GAL3ST4,RXRA,FAM214B,BTBD7,NMNAT2,KDM4C,ASTN2,KAZN,SYNE1,CRTC1,TNS1,ZNF24,PHTF2" Drug 2738_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "MTUS1,MRTFA,APAF1,PPP4R4,CASK,N4BP2L1,SYNJ1,CHM,EPS15L1,QKI,HOMER3,CYBB,DBT,DTNA,E2F5,FCF1,EFNA3,COQ7,NCALD,RRAGB,FHL1,ZMYND11,LILRA2,GRB10,LIG4,MAP4,MDM4,MEF2C,NF1,PDE3B,CCSER2,PILRA,MINDY2,PRKAB2,PTCH1,URGCP,SLC6A8,TMCC1,EMC1,UNC5B,TROVE2,NCDN,ATP11A,KAZN,TCF7L2,PSD3,CRTC1,ZNF34,CDK20,TPM3,ZNF24,PCBP4" Drug 5436_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "PLA2G6,C1QTNF3,ARHGDIG,MARK4,BRINP2,SYNJ2,SCAPER,BAIAP3,CFAP410,FADS2,ARHGEF6,ABI3BP,CRY2,SIPA1L1,SDC3,RUSC2,SMG7,DSCAM,DTNA,EFNA3,VPS13B,KAT8,FGFR1,IQCG,EFCAB2,INPP5K,GPER1,GRIK5,ELOVL5,IL6ST,MIA2,NDUFA5,NF1,PDE3B,LRP12,MBOAT7,NKAIN1,RAD52,SLC1A7,PPP4R3A,EPN2,MAPKBP1,EMC1,PLCB1,IQCE,PCDHA6,TGFBR3,VGF,WNK1,EMSY,ST7,SENP7" Drug 5309_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.99E-05 1.00E+00 8.87E-04 1.01E-02 52 197 "ALCAM,DNAH17,N4BP2L1,CFLAR,C5,SYNGR3,FAM189A2,VAX2,SMG7,DTNA,EGFR,ING4,ELN,CDHR1,VPS26C,FER,BAIAP2,GLYR1,TDRKH,GRM1,BTN2A1,PTGDR2,HNMT,MAP4,NRGN,PDE1C,PPP5C,WDR25,PTPRE,NKAIN1,RAB3A,ROM1,WLS,FNDC3A,DHX30,WDTC1,ZHX3,SPTAN1,CDK19,THSD1,NXT2,JMJD6,ATP11A,MCF2L,TBL1X,TCF7,TRIM2,TNS2,PCDHA5,ZMYND8,TSN,ZNF24" Drug CID000002878 CPPG Stitch 8.01E-05 1.00E+00 8.89E-04 1.01E-02 15 34 "CBS,GRIA1,GRIK1,GRIK3,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR2A,MAP4,SOX10" Drug CID000040159 trans-permethrin Stitch 8.01E-05 1.00E+00 8.89E-04 1.01E-02 28 86 "ACHE,NDRG2,ADCY2,ADCY5,ADCY6,ADCY8,API5,PDXK,BCHE,ASIC3,QKI,CP,DMPK,TRAPPC9,PHC2,ERBB2,AGAP3,GFAP,CSDC2,KCNA1,KCNA2,MATN3,RYR1,SCN4B,PUF60,SCN3B,SOX10,CAMK1G" Drug 7077_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.11E-05 1.00E+00 9.00E-04 1.02E-02 47 173 "ABHD6,ADRB2,ARNTL,ST3GAL5,CBFA2T2,ABCG1,PDE4DIP,CTH,PLPPR4,RGS17,F3,TAOK3,ATP8A1,TESK2,BAIAP2,GLS,GUCY1B1,DIPK1A,KIF5C,LIFR,MMP16,TAGLN3,PCDH9,SERPINI1,PIK3CD,RETREG1,SYTL2,TMEM104,RAB3A,RGS4,FBXW7,FAM102A,SH3GL2,ASAP3,FAM214B,KDM4B,DOP1A,BEX1,ARHGAP26,THSD1,RGL1,PHLDB1,SYT1,KIAA0930,TGFBR3,DNAJC12,PLSCR4" Drug CID000005665 vigabatrin Stitch 8.12E-05 1.00E+00 9.00E-04 1.02E-02 19 49 "ABAT,PDXK,SLC32A1,ELN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,MEST,SLC6A1,SLC6A11,TSC1" Drug ctd:C558013 NSC 689534 CTD 8.27E-05 1.00E+00 9.17E-04 1.04E-02 301 1570 "ASIC1,RNF157,CDC7,KLHL13,KIAA1324,WDR35,AK2,SRPX,APBA2,EPB41L5,ALS2,CACHD1,LGR5,ARNTL,ARRB1,ASPH,ZSCAN18,ALDH7A1,BACH1,BARD1,SEC11C,BCHE,BID,BLM,CFLAR,PROM1,DST,C5,CACNA1A,PRC1,SCARB1,ARHGEF2,CCPG1,CLGN,NOG,ADGRG1,CHM,CHN1,ARHGAP22,CLCN4,CLU,QKI,AHCTF1,HS3ST5,PREPL,CREM,AKAP12,HAPLN1,TENM4,PHACTR3,FAM169A,SLITRK5,PITPNM3,APPL1,PHF14,PLCXD3,PNPLA8,CTH,FAM131B,ARHGAP32,FGFR1OP2,PHF19,EARS2,DBI,AIF1L,RUSC2,DDX46,RHOBTB1,AK5,RAB39B,NR1D2,CPEB2,SLC12A6,ARRDC4,ECM2,DUSP9,GOLT1B,EDN1,TMTC1,FRY,OPTN,RBM12,FAM13A,EGFR,KMT5B,LPAR6,EIF5,ELAVL2,EIF1,ENO2,TMEM74,SIRPB1,CD320,TBC1D16,TUBA1B,EFEMP1,ATP8A1,CEP78,TOMM40L,GTF2IRD2,FGF1,AMOTL2,SCARA3,SYNCRIP,FOXM1,SEMA4D,FLNC,NOP56,EFCAB2,DPYSL4,SORBS1,TRIM16,OGA,FYN,SDCBP2,GAB1,DENND2A,NEK6,ERAP1,ACSS1,DNER,FAXC,C1QL1,RND1,GLUL,KDM2B,KCNMB4,GNAL,FERMT2,PSRC1,GPM6B,NUDT21,CIT,TMEM25,FICD,GUCY1A1,HAS2,BACH2,HMGB1,HSPA1L,IDH3A,IFI16,SCIN,IL6ST,ZNF678,JAK2,SLC35G1,KCNK2,CREG2,KIF5C,L1CAM,LAMP2,STMN1,NCOA7,LSS,MAP2,AQP11,MATN2,MBD1,MBNL1,CHIC1,MDM4,MIA2,CCDC80,MT1M,THYN1,MYO5A,HNRNPM,NAP1L2,NASP,NCF2,NELL2,NFIA,NME4,NRGN,CLDN11,PBX1,PDE1C,PDE3B,PDGFRA,ENPP2,SLC10A4,GNG2,NALCN,ANLN,GPSM2,JAKMIP1,SLC25A23,PCDH18,FA2H,POU3F2,PRKAB2,CEP41,PRPH,LRRC49,SIDT1,PTHLH,STK32A,PTPRB,PTPRD,PTPRH,FAM120C,PTX3,RADX,VEPH1,UBR7,RGS4,RGS7,RGS12,TTLL7,SLC25A36,RAVER2,MCMBP,RIMKLA,RPS6KA2,MAP6D1,PTGR2,RTKN,CLIP1,TMEM156,FOXRED2,MAPK12,CSRNP3,SCN8A,FNIP1,HES6,FOXRED1,ASRGL1,SCG5,SH3BGR,FAM102A,CPEB3,HKDC1,CNKSR2,BCAN,SLC1A3,FAM81A,SEPHS1,SLC8A1,SLC9A5,SHANK2,CPEB4,MYH15,TTC17,LIMCH1,PALLD,FAM219A,TRERF1,KDM3A,NMNAT2,BEX1,ARHGAP26,CDK19,ZBTB43,FCHO1,SEPT8,CEP68,SULF2,ARC,SYT1,ASTN2,ANKRD12,MTCL1,DNMBP,KLHL4,TCF4,SYNE1,OBSL1,SLC35G2,SPX,GPR161,HEY1,TIMP4,CBX5,TMPO,TPD52,TPM3,PDSS1,NEIL2,UBTF,SLAIN1,OSBP2,VLDLR,NSD2,CLDND1,KCNT2,ATP6V0E2,TMEM237,PLPPR5,LRP8,RNF103,TMEM178A,NAV3,MVB12B,PLSCR4,RTN4,HNRNPA3,NUP214,FAM219B,MSRB3,FRMD6" Drug CID000082686 cresyl violet acetate Stitch 8.32E-05 1.00E+00 9.22E-04 1.05E-02 22 61 "ACHE,SLC12A5,FGF17,CA4,CALB1,CALB2,NCAN,BLOC1S6,ELAVL3,ENO2,PPP1R1B,GAD2,GFAP,GRIK1,ITGAM,BCO1,NTRK3,PEX5,BCAN,SLC1A3,SYN2,SYP" Drug 4554_UP Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.37E-05 1.00E+00 9.28E-04 1.06E-02 48 178 "OSBPL1A,CDK13,NRP2,SYNJ1,EPS15L1,ABCG2,HOMER3,CREM,SH2B1,CSF1R,DAPK3,DNAJC6,ZNF804A,MFAP3L,RABGAP1L,EDN1,SGK2,ST3GAL6,ZNF589,FGFR1,SORBS1,B4GALNT1,GCNT2,GLS,GPR19,GPR22,CACFD1,ELOVL5,DIPK1A,KCNB1,MX1,NCF2,OXTR,PAK3,KHDRBS2,RGS12,TTLL7,HSPA4L,CNKSR2,SOX15,ACSBG1,JMJD6,SEMA4A,ZEB1,PCDHGA10,AHCYL2,EVI5,MVB12B" Drug 5779_UP Ellipticine [519-23-3]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.37E-05 1.00E+00 9.28E-04 1.06E-02 48 178 "LGR5,RASL11B,SLC4A4,SLC16A4,CHGA,RAB33A,CLU,SH2B1,RIMS3,MFAP3L,PLPPR4,EDIL3,EDN1,EGR3,FGR,CSPG5,SYT17,ATP8A2,RND1,GNAL,GNG3,GPM6B,LAMA2,NEFM,NEFH,NHLH1,NPPA,NPTX1,NPTX2,PALM,PCDH9,PMP2,LRRN3,PTCH1,PTHLH,ENOX1,GAL3ST4,RGS4,PNMA8A,RPS20,KCNIP1,SGK1,SOX11,SYT11,ARC,TMOD1,PRDM2,DPF3" Drug 7498_DN irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.61E-05 1.00E+00 9.54E-04 1.09E-02 49 183 "MAP4K3,PPFIA1,APBB2,ATP2B1,BARD1,ARHGEF7,MAP7,LARGE1,NIPBL,FBXL5,DSCAM,DYRK1A,RASGRP1,VPS13B,EPS8,TAOK3,CHST15,SEC24B,SYNCRIP,DIDO1,BRINP3,NFE2L2,CNOT4,PIK3R1,PPP3CA,REV3L,SCAF8,CHD9,FBXO11,ATF7IP,SRPK2,TAB2,ERBIN,NEK4,SYT1,CAMSAP2,EHBP1,TCF7L2,WASHC4,NSD1,FRYL,TIAM1,TJP1,TMPO,TRPS1,ZMYND8,UBE3A,PRDM2,FXR1" Drug CID000004473 nicardipine Stitch 8.62E-05 1.00E+00 9.55E-04 1.09E-02 41 145 "AGT,ARHGDIG,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,KRIT1,CACNA2D2,CHN1,CHRM1,CHRNA4,CHRNB2,FADS2,ABCG2,EDN1,EDN3,EDNRA,EDNRB,CACNG7,CACNG3,CACNG2,DNER,MAP4K5,BCO1,NPPA,ABCB1,PKD1,RYR1,RYR3,TAC1,TPCN2,PDIA2,NUP214" Drug CID000003733 AC1MU1S9 Stitch 8.78E-05 1.00E+00 9.72E-04 1.11E-02 124 572 "KLRC4,ADCY5,ADCY6,ADCY8,ADORA2A,AGT,MYH7B,PHF12,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA2D1,CALM1,CAMK2B,CAMK2D,CAST,CCK,KRIT1,CD86,LRBA,NUMBL,CHN2,CHRM1,MYL6B,CNR1,NRG2,CREM,PLCXD3,CYBB,B3GAT3,EDN1,IRAK4,IGSF6,PTK2B,FCGR3A,ACTL6B,NELFCD,CAMKK2,ATP2C1,FYN,IQGAP2,ERAP1,BRD8,KCNMB4,NUDT21,PLCD4,GRIK1,GUCY1A2,GUCY1A1,GUCY1B1,IRAK3,PTGDR2,TNFAIP8L3,HPCA,MYLK2,IL12A,ITGAM,KCNMA1,KCNN1,KCNN3,ASPRV1,MBP,MEF2C,SCAMP5,MYL3,NCF2,NFIA,NOS1,NPR2,OGDH,OLR1,OXTR,P2RX7,TREM2,PDE1C,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,EPN1,LRP12,PPP3CA,PPP3CC,PRKACB,PKIA,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTHLH,PTH1R,PTK2,RASGRF1,RASGRF2,RIT2,SATB1,SELL,SGK1,SNAP25,PEG10,NFASC,PLCB1,SYN2,SYT1,ACTR6,CABIN1,PIK3R5,TRH,TRPC3,TRPM2,VGF,VSNL1,STMN4,PLD4,NUP214,NETO1" Drug 4386_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-05 1.00E+00 9.77E-04 1.11E-02 50 188 "DPF1,ASIC1,NDRG2,LTBP4,AMPH,CDC42BPA,APAF1,KCNAB2,CDC14B,RGN,CLGN,GPR37L1,TAOK2,WHRN,CSF1,VCAN,ARHGAP24,ELMO1,DLG4,ATN1,EFNB3,MBNL2,EGR3,PIPOX,EXTL1,DCTN2,FUT9,NEU3,GLS,GPER1,SLC2A6,HMGCR,IL11RA,LSS,GIT1,ZNF493,MRAS,SH3BP2,SH3GL3,ASAP3,SNCA,SOX10,TRIM2,PCDHGB6,TK2,WIPF1,XRCC4,ITM2C,PARP11,PAK5" Drug 4385_UP Thiostrepton [1393-48-2]; Up 200; 2.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.83E-05 1.00E+00 9.77E-04 1.11E-02 50 188 "BIN1,APAF1,SEMA4G,ASCL1,ATP2B2,BMP7,BAIAP3,CFAP410,CALB2,TAOK2,CLCN4,SULT4A1,CREM,NCOR2,CSF1,INTS1,SRGAP3,ELN,C3orf18,RASGRP2,DLC1,HPCAL4,EFCAB2,GAD1,RND1,GLS,GRB10,SYNPO,IL6R,VWA5A,AFDN,MOBP,OPCML,PALM,ENPP2,EPN1,RGS4,RGS10,FAM214B,SNCA,KIF21B,SP2,SPTB,SYT11,SYT5,POPDC3,DOCK9,UCHL1,VLDLR,KCNAB1" Drug 5958_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.83E-05 1.00E+00 9.77E-04 1.11E-02 50 188 "ASIC1,ARID1A,ADCY6,KIDINS220,AK2,APAF1,GAS7,CFLAR,SEPT7,CDC42,TAOK2,LHX2,STOML1,HOMER3,PICK1,AKAP7,CSF1R,VCAN,CNTNAP2,SLITRK5,FAM131B,EFNA3,GAD1,ZMYND11,DISC1,GLRB,GPM6B,TDRKH,KIFC3,ZNF862,NPR2,SLC11A2,PALM,PLXNB1,SAFB,ARHGEF40,RBM34,TROVE2,COBL,PDLIM2,TCF4,TCF7L2,TNS2,CRTC1,TRPC1,OSBP2,LAT2,ZNF711,TRIM9,TFIP11" Drug 2729_DN Securinine [5610-40-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.83E-05 1.00E+00 9.77E-04 1.11E-02 50 188 "ASIC1,ADRB2,MRTFA,AMT,APBB2,ADAM23,ST3GAL5,CLCN4,OSBPL3,SLITRK5,PPP1R16B,CX3CR1,DTNA,TNK2,PLEKHO1,RASGRP2,FGFR1,PCYOX1,CAMKK2,FYB1,SEPT9,MSL3,RAB40B,IRF8,MAP4,ZNF862,NRGN,OGG1,GPR85,PLTP,PTCH1,PTX3,SATB1,SEC14L1,ITSN1,SLC2A5,ARHGEF40,SLC20A2,TSPYL2,TROVE2,ZC4H2,KANK1,FAM168A,KAZN,KIAA1107,THBS4,RBFOX2,TRIM9,ZNF74,REEP1" Drug 4310_DN Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.83E-05 1.00E+00 9.77E-04 1.11E-02 50 188 "PDXK,ASPH,ATM,ADAM15,CFLAR,SPAG9,ARHGEF2,SRSF11,FCF1,SIDT2,CGREF1,ERAP1,SRCAP,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,AGFG1,IL6ST,INPP5B,MAP4,NFIX,SLC11A2,NUMA1,CCSER2,NLE1,STRN3,PPP3CA,PKN2,PTN,PLEKHB2,SLC25A36,KIRREL1,SEC14L1,ASAP3,CCDC88A,CDK19,ZBTB43,TBL1X,EHBP1,TRIM2,DICER1,TMPO,R3HDM1,SF1,ZBTB38,WNK1,PRDM2,KAT6A" Drug 4306_UP Deltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "BEGAIN,APAF1,CDK10,PPP4R4,ASCL1,KIF1A,CACNA1D,ADGRG1,CHRNB2,RAB33A,SULT4A1,DAPK3,MFAP3L,ATN1,DSCAM,EDN3,SORBS3,FABP7,FGF12,HBS1L,SEPT9,ALDH1L1,SRCAP,ADAM28,CSDC2,GNAL,ATF7,GPR19,GRIK5,KLF12,ITGA7,KCNB1,KCNK2,LSAMP,NCAM2,OPRL1,PFKFB4,LRRN3,PTPRN2,TRIM46,NTNG1,SLC1A2,PKNOX2,SLC11A1,SNCA,ZHX3,ACSBG1,TAC3,MCF2L,DOCK9,TRPC1" Drug 6050_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ASTN1,ATP1A2,INA,CLCN4,PCYT1B,NCOR2,CNTNAP2,SDC3,MYEF2,CNIH3,SPOCK3,ATN1,RCAN1,ST8SIA3,SRPK3,MTSS1L,KCNMB2,ERCC2,SPEG,PIPOX,CEND1,F5,TUBB4A,ZNF589,FGF13,AFF2,GAD1,GAD2,GPR162,RUNDC3A,ATF7,GRM8,KLF12,CD200,PCBP3,CDK14,FAT4,TTLL7,MYH14,SH3GL3,ASAP3,HKDC1,PKNOX2,SNAP25,FAIM2,TNIK,PEG10,RGL1,TRIM2,CRB1,SLC17A6" Drug 4186_DN Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "APC,ARRB2,RAB28,DNAJB5,IQCK,RGS6,SDC3,SNPH,BRINP1,ATN1,SORBS3,MTSS1L,SEMA4D,FYB1,GAB1,PRRC2B,LPAR4,GRIK2,GRM8,SOX21,SHISAL1,LMO2,MAPT,NOVA1,ODF2,PBX1,ENPP2,RETREG1,POLG,PROX1,PTPRB,RGS4,SBF1,IL17RB,FRMPD1,KANSL3,MYH15,SOX2,IQCE,TNS2,TIAM1,TIMP4,UBTF,UGT8,VGF,VIPR2,MICAL1,NDRG4,EVI5,KCNAB1,TIGD6" Drug 6677_DN Ciclopirox ethanolamine [41621-49-2]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ADRB2,APC,MARK4,BCL7A,BTRC,CACNB2,CDC25B,CHN2,HOMER3,WHRN,NRG2,DZIP3,DCAF4,TOX,CNIH3,RABGAP1L,CHRDL1,PLXNC1,COQ7,LRRC23,ERCC2,KIAA1109,HPCAL4,DCTN2,TRAF3IP2,ZNF274,GNAL,PSRC1,SPACA9,HLF,VWA5A,NDUFA5,NF1,NOVA2,ODF2,PBX1,PLXNB1,CNNM2,PID1,ZFP30,ANKRD6,RPH3A,ATF7IP,IQSEC2,KAZN,TCF4,SLC44A1,THRA,TNS1,UGT8,NAV3" Drug 4443_DN "radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "AMPD3,APBB2,APC,APP,MTMR9,ADGRB2,SCAPER,IL33,FOXN3,LHX2,PLAA,AKAP7,AATK,DUSP9,HIPK3,SIDT2,CELSR3,STX2,ERCC2,NCALD,DPYSL4,SYT17,KLF12,ICA1,SHISAL1,IL11RA,JAK2,GIT1,NF1,CNOT4,PFKFB2,PLCB2,RGS4,ROM1,TMEM206,RXRA,ATXN7,SLC1A7,ARHGEF40,TSNAXIP1,DDN,SMG6,ZEB1,AHCYL2,CABIN1,TNS1,UGT8,XRCC4,ZNF24,SEMA3B,PHTF2" Drug 6749_DN Zaprinast [37762-06-4]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "RALGAPA1,ASIC1,ARID1A,ADD1,MRTFA,ANK3,APC,APP,CDC14B,ARHGDIG,PDE8B,ATP2B2,KIF1A,ADAM23,CACNA1I,CHM,PDE4DIP,ARHGAP32,CTIF,EDIL3,ST8SIA3,EDNRA,AASS,EIF4G2,SPEG,ZNF589,FYB1,LYVE1,GRM1,KIF5C,MBD1,MYT1,NEUROD1,NUMA1,PIK3R1,EPN1,PMS2,TNPO2,FSD1,SYTL2,DZIP1,WDTC1,RBM26,DDN,TROVE2,SS18,SSBP2,LAT2,NT5M,KCNAB1,NUP214" Drug 3057_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ACTN2,KIDINS220,NUMB,KIF1A,BACH1,CACNB2,CLGN,TAOK2,EPS15L1,CLCN4,STOML1,RIMS3,MBNL2,ELAVL3,COQ7,ERBB2,DLC1,KIAA1109,GAB1,GABRA2,SEPT9,INPP5K,ADAM28,LILRA2,KCND3,MAP4,MID1,MYO6,NNAT,NOS1,P2RY1,PDE4A,PFKFB2,RETREG1,SLC25A23,WDR25,RAD52,SH3BGR,FAM102A,CPEB3,PEX26,SPTAN1,SPART,MAPK8IP3,SYN2,TBL1X,PSD3,TRPS1,CLIP2,PHTF2,NUP214" Drug 4161_DN Cefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "AP2A2,NME5,AK2,APBB2,APLP1,ARRB1,PLA2G4C,RASL11B,SYNJ2,BTRC,CFAP410,CACNA1D,RIMS2,GPRASP1,MFAP3L,PARD6A,HIPK3,EFNB3,ING4,SCML2,ATP8A1,ZNF589,KIAA1109,CAMSAP1,GCNT2,KCNK2,KCNQ3,IPO5,MAP4,MDM4,ADAM22,CDK18,PLCD1,PRKAR1B,MAPK10,PTHLH,TRIM68,RGS10,SLC9A5,KIF13A,THSD1,ST5,FAM168A,POPDC3,MCF2L,TBCEL,WSCD1,ARHGEF12,TMEM121,PARD3,WIPF1" Drug 2383_UP Norethindrone [68-22-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ARRB1,PDE8B,ZSCAN18,ALDH4A1,N4BP2L1,AZGP1,ST3GAL5,SLC24A2,DCAF4,ARHGAP24,MYEF2,GSDME,DSCAM,DTNA,MBNL2,RASGRP2,FHL1,MYOZ2,GLYR1,KIF3A,FAM107A,ADAMTS6,NXPH3,KLF12,ICA1,SCIN,KCNJ5,LSS,NF1,NINJ2,KCNK10,PDE3B,PDE4B,PENK,PLP1,PLTP,MASP1,RNASEL,SLC8A1,SHANK2,SLC20A2,PALLD,ZSWIM8,SS18,MAPK8IP3,MCF2L,TBL1X,CUX2,RBFOX2,SSBP2,ZBTB16" Drug 7229_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "AK2,GAS7,AQP4,ARRB1,SCAPER,CAMK2B,ARHGEF1,CBFA2T2,SRSF11,SOCS6,TPP1,IFFO1,HAPLN1,CSNK1E,SDC3,PPP6R2,DCAF4,BRINP1,EGFR,MBNL2,HSD17B14,OLFM1,BAIAP2,GLYR1,POLL,PRUNE2,GPER1,GRM8,NPR2,SERPINE2,PRODH,PRPH,WDR25,PTAFR,ZSCAN32,PEX5,CRTAC1,PREX2,WDTC1,KDM4C,PLCB1,SYT5,EXOC7,PCDHGA10,CRTC1,ZNF34,TK2,RUNDC3B,LAT2,SLC17A7,RNF170" Drug 5985_DN Norfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "FAM131A,APOC1,PPFIA3,ATM,CFLAR,ST3GAL5,SYNJ2,SCAPER,UBE2L6,TAOK2,HOMER3,AKAP7,NCOR1,FEZ1,CNTNAP2,GREB1,KIAA0586,GIT2,HP1BP3,DRD1,SUGP2,IRAK4,ZNF589,RAB30,GRM1,KCNF1,MAPT,GIT1,LYRM9,NF1,PBX1,SAMD9,GTDC1,ARHGEF10L,FBXW7,PAQR6,ANKRD6,FAM214B,SPTAN1,IQSEC2,ELOVL4,ASTN2,KAZN,MCF2L,EXOC7,ZMYND8,VIPR2,XRCC4,ZFP37,TFIP11,MPPE1" Drug 6625_DN Hydrochlorothiazide [58-93-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "NME5,ALAD,ST3GAL5,CLCN4,AKAP7,CREB5,SLITRK5,CNIH3,SMG7,EXOG,CDON,SIDT2,LRRC23,ZNF549,FKTN,FGFR1,PDLIM5,ZMYND11,ERAP1,SEPT9,GCNT2,SESN1,ZNF276,GNAS,GPD2,STON1,SPACA9,DHX35,TJAP1,KCNK1,LIG4,LYRM9,CNOT4,PPP2R5C,MAPK7,RALGDS,SH3TC2,ZCWPW1,KIRREL1,ZNF821,AMBRA1,FNDC3A,ZBTB43,DDN,THSD1,SS18,SEPT8,ASTN2,FBXW11,RPGRIP1L,WIPF1" Drug 3183_UP "Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "SYN3,ADGRF5,APLP1,APP,PRX,PPP4R4,ARHGDIG,CADM3,AZGP1,NRP2,CACNG1,CAMK2B,WHRN,PLCH2,CNTNAP2,EDRF1,C2CD2L,SV2B,OLIG2,EFS,HPCAL4,AGAP2,KHDRBS3,DISC1,INPP5K,GLI2,GNAL,GRIN1,NR3C1,GRM1,KCNMA1,MAP4,MAPT,MARK1,MEF2C,AFDN,ADAM22,PDE4A,PDE4B,KCNIP2,PKNOX2,SHANK2,SYT11,SYT5,TCF4,TEK,TNS1,KCNK12,ZNF45,NT5M,SCG2" Drug 3200_DN Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ABHD6,AK2,MRTFA,FAM131A,SEMA4G,MARK4,CAPRIN2,SLC4A4,CFLAR,CACNA1I,BAIAP3,KYAT1,SCARB1,CSF1R,ATRNL1,CYBB,SPOCK3,MED12,DTNB,EIF4G2,EN2,ENO2,F3,FGFR1,FHL1,GABRA2,ZNF44,SRCAP,GFER,PRUNE2,LPAR4,GRB10,GRIK5,GRM1,MAP4,MIA2,MSI1,NF1,GON4L,SNRK,PTPRO,RGS10,FNDC3A,SLC1A7,EPN2,LIMCH1,VAMP1,KAZN,DOCK9,TRPC1,EPM2A" Drug 3712_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "C1QTNF1,ADGRF5,ALK,APC,GAS7,SLC4A4,ALDH7A1,ADGRB2,SCAPER,IL33,CBFA2T2,ZFYVE9,CLCN4,SH2B1,ABCG1,DAPK3,SMG7,SPOCK3,CDON,DUSP9,ING4,ETV1,CORO2B,ATP8A1,SEMA4D,GNG4,GPM6A,BACH2,SHISAL1,KCNMA1,ADAM22,NFYA,NUMA1,MINDY2,CEP41,PTHLH,RAB3IL1,RAD52,RGS7,GSTCD,CSRNP3,ZNF821,FAM214B,WSCD1,TEX15,DNAH7,TPM2,VIPR2,WNT7A,REEP1,UPF3A" Drug 6664_DN Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "BIN1,SYNJ2,ARHGAP33,CLCN4,ABCG1,PDE4DIP,TBC1D5,DBT,CNIH3,FBXL5,SMG7,EXOG,HIPK3,FCF1,CELSR3,TENM1,EPB41L2,LRRC23,VPS26C,SCML2,FYN,GAD1,GART,GLS,LPAR4,GRM8,HLF,KHK,MPP2,NDP,NF1,SLC11A2,NLE1,PTPRE,PID1,NUDT11,KIRREL1,ZNF671,MAPK12,FBXO11,EMC1,ELOVL4,IQCE,ZEB1,TNS1,SMUG1,TRIO,VGF,WIPF1,SEMA3B,TIGD6" Drug 5273_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "SPARCL1,BCL2L2,ST3GAL5,CACNA1I,CFAP410,DLGAP1,CACNA2D2,FOXN3,SNCAIP,CSF1,SEC14L5,SPOCK2,DYRK1A,SIDT2,EFNB3,PLXNC1,RASGRP2,NRN1,GABRA2,GAD1,GCNT2,GFER,PRUNE2,GRIK5,GSN,IL6ST,KCNJ5,MAP4,MDM4,LRP1B,AFDN,MYT1,P2RY13,NTRK2,CDK18,PLCD1,PPARA,PTPRD,FAT4,ZNF821,SH3BP2,SLC2A5,ARHGEF40,SNCA,RGL1,FAM168A,ATP11A,SMG6,SLC44A1,HEY2,CABIN1" Drug 6587_UP AG-028671 [847803-03-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ABR,KIDINS220,ALCAM,APP,STX16,CFLAR,SPAG9,TAOK2,QKI,PDE4DIP,DAPK3,G3BP2,DTNA,FCF1,OPTN,HSD17B14,ZNF589,ANKFY1,PDLIM5,GPR153,ZMYND11,ARFIP1,HTATSF1,MAP4K5,LSS,MMP16,ZNF862,NFYA,CNOT4,NUMA1,PDE3B,PLEC,SYTL2,RALGDS,TRIM68,RNASEL,ASAP3,ZNF365,ELMO2,RCOR3,SS18,ST5,CHST8,RBFOX2,TPM1,UBE2H,VLDLR,SH3GLB2,UBE3B,RNF170,FXR1" Drug 2509_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ADD2,ADORA3,ALK,ARHGDIG,PDE8B,ASPH,AZGP1,CAMK2B,CLCN4,RAB26,CRY2,ARHGEF10,CTNND2,ARNT2,TRAPPC9,DYRK1A,AASS,SIGLEC8,GLUL,GNAL,GRIN1,ADAMTS8,HPSE2,IL6ST,IL12A,KCNN1,MPP2,ADAM22,NCAM1,NF1,NRCAM,PDE4D,ABCB1,MTRF1L,MARCH1,SEC14L1,ASAP3,NLGN1,DOK5,INKA2,TACR1,TBL1X,TRIM2,HIF3A,TLL2,TMOD1,TRH,TRO,FLRT2,ZBTB16,SSPN" Drug 6102_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ASIC1,ADORA1,NME5,TRMT9B,CFLAR,BMP7,BTRC,CFAP410,CA4,CACNA1D,CACNA2D2,FOXN3,ABI3BP,JAKMIP2,ZNF804A,DUSP9,EFNB3,C3orf18,ERCC2,FGFR1,SEMA4D,GPER1,GRM8,RASSF8,ATXN2L,ELOVL5,ITIH2,TM6SF1,MPP2,ADAM22,NF1,NOS1,ZNF821,SH3GL3,ASAP3,NLGN1,FAM214B,SLC6A8,KDM4C,ARHGAP26,PHLDB1,SUPT5H,SYN2,ROBO3,TBCEL,TEX15,TK2,PARD3,TPM1,PLPPR2,KAT6A" Drug 2131_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "ADCY2,ADORA1,BIN1,SEMA4G,CASK,MTMR3,MAP7,STOML1,CABP1,CRY2,PDE4DIP,USP6NL,DAPK3,CDON,DSCAM,EIF4G2,BSCL2,TUBD1,DMTN,FOXG1,NBEA,GALC,ZNF276,TJAP1,KCNJ5,KIF5C,MSR1,NUMA1,P2RY1,PGAM2,WDR25,RAB3A,PID1,GAL3ST4,ZMAT4,TTLL7,STUM,RPH3A,MYH15,IZUMO4,ZBTB43,SYN2,DNMBP,CAMSAP2,TBCEL,ZNF34,PRMT8,SMUG1,FZD3,MARCH8,SENP7" Drug 3614_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.02E-05 1.00E+00 9.88E-04 1.12E-02 51 193 "AP2A2,NME5,ALCAM,DOC2A,BIN1,CFLAR,RAB28,BAG4,SH2B1,GREB1,HIPK3,SUGP2,ZNF589,FGFR1,CGREF1,DISC1,USP19,GNG4,SPACA9,MAP4K5,INPP5B,KCNN2,MMP16,NF1,PFKFB2,EPN1,MAPK7,MAPK8,PRPH,RGS12,KCTD17,GSTCD,ROM1,TCP11L1,PAQR6,ANKRD6,BTBD7,CXXC4,SMARCD3,SOX2,DOK5,UNC5B,INKA2,PLCB1,TBCEL,ARHGEF12,FAM155A,FLRT2,EVI5,KAT6A,PHTF2" Drug CID000446755 P-NE Stitch 9.14E-05 1.00E+00 9.88E-04 1.12E-02 46 169 "ADORA1,ADORA2A,ADORA3,ADRB2,ARRB1,ARRB2,ASCL1,PDE8B,ALDH7A1,RIPK1,RGS9,CALM1,CBFA2T2,LRBA,CNGA3,CABP1,AKAP5,GIT2,ETV1,PPP1R1B,AKAP3,DISC1,GNAS,CNDP1,GPD1,GPD2,MYLK2,NAP1L2,NCAM1,NOS1,NPPA,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,SERPINE2,PRKACB,PEG10,SSTR2,TBL1X" Drug CID000127988 "4,6-dichloroindole-2-carboxylic acid" Stitch 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "B3GAT1,GRIA1,GRIA2,GRIA4,GRM3,TACR1" Drug ctd:C005238 mipafox CTD 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "ACHE,BCHE,GAP43,NEFH,SYN1,SYP" Drug CID011051569 fluorocyclobutane Stitch 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "ABHD6,GRIK1,GRIK3,GRIK4,GRIK5,SCN2A" Drug DB01589 Quazepam Drug Bank 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug CID000197303 Be 18257b Stitch 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "EDN1,EDN3,EDNRA,EDNRB,IGF1,IGFBP1" Drug CID000005370 "azetidine-2,4-dicarboxylic acid" Stitch 9.17E-05 1.00E+00 9.88E-04 1.12E-02 6 7 "STX2,GRM1,GRM2,GRM3,GRM5,GRM8" Drug 5108_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BIN1,MARK4,ALDH4A1,ALDH7A1,CACNA1A,CDC42,LARGE1,CHN2,DNAJB5,WHRN,RCHY1,EDRF1,BRINP1,SMG7,SPOCK3,CDON,EDIL3,EDNRA,MBNL2,ATP8A1,BAIAP2,GAB1,GNAS,IL12A,MATN3,TAGLN3,NEK1,NF1,PDE4A,MED1,BCAS3,PID1,RGS4,ARHGEF10L,ROM1,CSRNP3,SLC20A2,SNCA,RBM34,TROVE2,NXT2,SYN2,SYT1,KIAA1107,TNS1,METTL3,TRPC1,ZNF24,ZNF225,EVI5,SEMA3B,SENP7" Drug 5213_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASIC1,ADORA1,C1QTNF1,SEMA7A,APBB2,MARK4,ASPH,CACNG1,CDH2,ARHGAP33,CLGN,STOML1,LY86,ENTPD4,CTH,RUSC2,SMG7,ATN1,EFNB3,ZNF589,FGF13,FGFR1,BAIAP2,FHL1,FOXG1,SIGLEC8,RUNDC3A,POLL,GNAO1,GRIK1,HLF,KHK,ZNF862,OMG,NECAB2,PPP5C,PTHLH,RAD52,RALGDS,RGS10,RGS12,PNMA8A,ZNF821,SLC20A2,LIMCH1,WDTC1,DOK5,HECW1,ABCC8,ARC,MCF2L,CDK20" Drug 4724_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASPHD1,ABHD6,ADRA1D,AK2,MRTFA,BIN1,CDC14B,RGS20,MTMR3,EPS15L1,AKAP7,WHRN,CRY2,CSF1R,BRINP1,SPOCK3,DRD1,AASS,ERCC2,ZNF589,FHL1,C1orf61,FYB1,GFER,GNG4,PRUNE2,DHX35,KCNN1,KPNA5,MGAT3,GIT1,NEUROD1,NF1,NNAT,RETREG1,PTN,RAB3IL1,ZDHHC14,RGS10,FAM214B,PKNOX2,KIF13A,SPTAN1,ATP10B,PSD3,TMOD1,VLDLR,XRCC4,MAP3K12,DNALI1,HPS4,TIGD6" Drug 1551_UP Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "APBA2,SHTN1,PDXK,ARNTL,ATP2B1,SCAPER,KRIT1,CCNT1,ARHGAP33,SRSF11,NIPBL,CNTFR,SLC4A7,BAG4,SEC31B,CLOCK,KLHL3,ANKRD46,SIDT2,EGR3,ING4,EPB41L2,SEC23B,INPP5K,CRCP,GLS,OS9,GNG3,ITGAM,KCNJ3,MYT1,NEFH,NUMA1,MED1,PPP2R5C,CNNM2,CCDC40,AP1AR,ELMO2,WDTC1,ZC3H13,TSPYL2,LARP4,CEP68,SYT1,MCF2L,PARD3,SEZ6L,TRIM9,EVI5,AAAS,DPF3" Drug 7332_UP Beta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AP2A2,LTBP4,ALK,PPP4R4,ASPH,CAMK2G,USP2,CHM,HOMER3,NOS1AP,JAKMIP2,RABGAP1L,KBTBD11,GNE,EGFR,DLC1,ZNF589,FGFR1,IQCG,SEPT9,SRCAP,RUNDC3A,POLL,GPM6B,GPR19,STON1,NR3C1,GRM8,SOX21,TJAP1,IL6ST,KCNN1,NF1,NPTX1,NLE1,GON4L,ZSCAN32,RALGDS,RGS12,ZFHX4,ZNF821,SH3GL3,ABLIM3,SLC1A7,WDTC1,ZCCHC24,STX1A,ADGRL3,RPGRIP1L,AP4E1,CHST5,SSPN" Drug 7294_DN Imipenem [74431-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BRAP,PPFIA3,ASPH,SLC4A4,STX16,BID,ST3GAL5,SCAPER,HIP1R,REPS2,CHN2,BAG4,ENTPD4,APPL1,RABGAP1L,DNM2,CINP,ZMYND11,COPS8,GLS,MAPT,MITF,NPR2,ODF2,PLCD1,POLG,PPP5C,KIRREL1,ITSN1,SCMH1,SLC22A4,LIMCH1,DOP1A,TNIK,SEPT8,ARHGEF9,SIN3B,ARHGEF12,ZNF34,TMPO,PARD3,SSBP2,ZKSCAN5,HIRA,PLPPR2,WNT7A,XRCC4,NDRG4,SPHK2,MAP3K12,EVI5,FZD3" Drug 3005_UP Suprofen [40828-46-4]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABAT,ACHE,TKTL1,SEMA6A,CDC42BPA,AQP4,ATP2B3,AZGP1,CACNA1G,HIP1R,CBFA2T2,SYNGR3,DGKI,CHGB,AKAP6,WHRN,RGS6,SNPH,MFAP3L,EXOG,ST8SIA3,ING4,SRPK3,KHDRBS3,GAD2,NEU3,GLI2,RAPGEF1,PTGDR2,SCIN,PACRG,MBP,AFDN,MSR1,MYT1,NOVA2,NTRK2,PCDH9,PPP2R2B,FAM120C,SLC6A15,RGS4,MYH14,SHANK2,PEG10,ATP10B,ROBO3,PHF24,HIF3A,TGFBR3,SSBP2,PRDM2" Drug 605_DN monastrol; Down 200; 20uM; MCF7; HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "C1QTNF1,AMPD3,CDK10,ASCL1,PDE8B,ALDH4A1,CADM3,ADGRB1,SYNJ2,CANX,SYNGR3,CHRM4,CHRNB2,CLTB,ARHGEF10,USP6NL,SGK2,EFNA3,EFNB3,CALCRL,COQ7,BAIAP2,FOLR2,SORBS1,RASL10A,ERAP1,LUZP2,HMX1,TREM2,PLCD1,PMS2,CEP41,MAPK8,ELOVL2,ZSCAN32,RGS4,TCP11L1,SELL,ZNF821,SH3BP2,KBTBD4,DOP1A,PEG10,ATP10B,SEPT8,EXOC7,TBL1X,TPM3,TRPC1,WNT7A,ZNF189,MPPE1" Drug 387_DN "estradiol, USP; Down 200; 0.01uM; HL60; HG-U133A" Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN1,BEGAIN,APOC1,AQP6,CADM3,ADAM15,BMP7,MAP7,CDH2,CACNA2D2,SLIT2,ZFYVE9,CLCN3,RAB26,RGS6,TBC1D5,C2CD2L,ING4,KAT8,ANKFY1,HPGDS,HTATSF1,PCSK1N,HMX1,KCNMA1,LYRM9,MYO9A,NEFH,DDR2,POLG,MED1,MASP1,VPS13C,PYGM,SUSD4,RGS12,RLBP1,RNF220,STUM,ASAP3,SMTN,ZC3H13,SRPK2,SST,ST5,CEP68,PHLDB1,GANAB,SZT2,NR2C2,TRIO,KLC2" Drug 2211_DN Astemizole [68844-77-9]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NDRG2,KIDINS220,AK2,APBA2,KCNAB2,SEMA4G,SLC4A4,ATP6V0A1,ADAM15,CACNA1D,TAOK2,LHX2,ARHGEF4,SEC14L5,CDON,EFNB3,EGFR,DMTN,TMEM164,CAMSAP1,SEMA4D,FAM49B,CSPG5,GLYR1,GPER1,SPACA9,GRIK5,CACFD1,GSN,MUM1,JAK2,KCNJ3,NRGN,MBOAT7,PTHLH,RAB3IL1,RGS10,GSTCD,NEK11,TCP11L1,MAP6D1,EMID1,IL17RB,SLC22A4,SMARCD3,WDTC1,EXOC7,ARHGEF12,VGF,ZIC3,SYNC,ACTR3B" Drug 3356_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,ADRA1D,BIN1,KCNAB2,PDE8B,BTRC,ZFYVE9,CNTN1,DCAF4,EDRF1,KBTBD11,DNM1,RCAN1,ING4,WAC,IQCG,DPYSL4,PDLIM5,FAM49B,GCNT2,MSL3,GRB10,CACFD1,KCNN2,KHK,LIG4,SMAD1,MAP4,PRKAR1B,MAPK7,WDR25,CCDC25,TCP11L1,RPS6KA2,ATXN1,PREX2,FAM214B,ZHX3,EMC1,ST5,MAPK8IP3,FAM168A,PLCB1,POPDC3,ATP11A,RPGRIP1L,VIPR2,XRCC4,ZNF45,PRDM2,SMIM8,SSPN" Drug 3673_UP Ofloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "DPF1,ACTN2,NDRG2,ADAM23,AZGP1,CACNA1I,CAMK2B,NEURL1,JAM2,SULT4A1,IFFO1,IPCEF1,NCAN,ERC2,CYBB,SPOCK2,HEPH,ATN1,ABCC9,RGS17,EPHA5,BAIAP2,EFCAB2,B3GAT1,GALC,CPLX2,GRK4,GRIA4,GRM1,GRM7,ITGA7,CD200,ADAM22,NF1,SEPT4,POU3F4,PTPRO,MYH14,STUM,ARHGEF40,SCN3B,ZNF423,AJAP1,SYN2,TACR1,DOCK9,CRTC1,PCDHA6,ICAM5,WIPF1,LAMP5,SEMA3B" Drug 7473_UP Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AMPH,BIN1,CDC42BPA,APOC1,MARK4,ALDH4A1,SYNJ1,USP2,ARHGEF10,ARHGEF4,DCT,CDON,RCAN1,EFNB3,EGFR,MRNIP,FAM198B,FGF13,SCARA3,AFF2,ARPP21,LPAR4,IL6R,INPP1,MDFI,MIA2,LYRM9,NF1,NPY,NPTX1,PALM,PLTP,MBOAT7,MAPK8,MAPK10,ZSCAN32,PTPRD,DPF2,RFX3,RGS3,RASA3,RPH3A,SLC1A7,SLC11A1,TSNAXIP1,SYN2,SMG6,PCDHA6,ATP13A2,KCTD2,HPS4,NUP214" Drug 6636_UP Harpagoside [19210-12-9]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASPHD1,MRTFA,APBB2,ATP6V0A1,ADGRB2,RGS9,SYNJ1,MTMR3,MYRF,BTRC,HAP1,MFAP3L,DTNA,EDN1,SEMA3D,F5,REEP2,FGF1,ERAP1,CSDC2,RND1,GNG4,KLF12,SMAD9,MMP16,MOBP,MSR1,NELL2,NEUROD1,ENPP2,RETREG1,EPN1,CNNM2,ELOVL2,PTPRB,C1orf54,RGS10,EMID1,PEX26,IZUMO4,BEX1,SPTB,CDK19,ATP10B,PHLDB1,ICAM5,RIMBP2,PRMT8,AMACR,ZMYND8,LAT2,KCNAB1" Drug 3901_DN U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,NDRG2,AP2A2,PLA2G6,MRTFA,KCNAB2,APBB2,GAS7,PLA2G4C,CDK13,ALDH7A1,CFLAR,CBFA2T2,PICK1,CRY2,NCOR2,DBN1,DRD1,ATN1,DMTN,LRRC23,FGFR1,FHL1,ATP2C1,B4GALNT1,GCNT2,SRCAP,NR3C1,GRM8,GSN,ATXN2L,ICA1,KCNH2,KITLG,NF1,NPPA,SLC11A2,TNPO2,ELOVL2,CCDC40,TCP11L1,RASA3,ASAP3,CDK5RAP2,LIMCH1,RGL1,SLC44A1,PARD3,PLPPR2,ZIC3,SYNC,SSPN" Drug 4064_UP Corticosterone [50-22-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASPHD1,AGT,ADGRF5,AQP4,ATP2B2,CADM3,GYG2,CAMK2B,ENTPD2,CHN2,TAOK2,CLCN4,PHF14,SEC14L5,SPOCK3,ARNT2,HS3ST2,ING4,LRRC17,RASGRP2,ZNF391,FABP7,HPCAL4,AGAP2,PRELID3A,DISC1,SRCAP,GNAO1,SPACA9,CACFD1,ELOVL5,LAMA2,VWA5A,MARK1,MATK,NCAM1,NF1,NPTX1,NPTX2,NTRK2,PAK3,PBX1,CCDC40,CNKSR2,ZNF334,IZUMO4,RBM26,ASTN2,TACR1,MCF2L,TRH,VAV2" Drug 435_UP "novobiocin sodium, USP; Up 200; 100uM; PC3; HG-U133A" Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASIC1,TKTL1,ADORA2A,APBA2,APC,GAS7,ARNTL,ATP6V0A1,BMP7,CACNA1I,NEURL1,CDH10,ARHGAP33,DLGAP2,CHN2,DSCAM,DTNB,SIDT2,EFNB3,EIF4G2,ELN,COQ7,FABP7,FER,FGFR3,DISC1,SRCAP,AHDC1,GFRA2,GRK4,MBP,AFF1,NOS1,SNTG1,RC3H2,ACSS3,ATXN7,ASAP3,SLC8A1,SNAP25,SPART,SSTR2,TBL1X,DMXL2,GPR161,SEZ6L,TRO,TUBB1,SLC13A3,SLC26A10,MPPE1,AAAS" Drug 3107_DN Adrenosterone [382-45-6]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "MTUS1,ANK3,APOC1,PDE8B,CAMK2G,ARHGEF1,ENTPD6,DNAJB5,AKAP7,CREM,SIPA1L1,DGKG,KIAA0753,RUSC2,C2CD2L,TNK2,CDKL3,PTK2B,DLC1,TPK1,CGREF1,CSPG5,GABRA4,ICA1,LAMA2,MAP4,MEF2C,AFDN,GIT1,ZNF862,NUMA1,OXTR,SLC25A23,SIDT1,PTAFR,ZSCAN32,ZCWPW1,ZDHHC14,FAM214B,ZHX3,CAMSAP2,PDLIM2,TCF7L2,PARD3,RBFOX2,TPD52,TPM1,ZKSCAN5,MKRN3,WNK1,GDPD5,TIGD6" Drug 4796_DN Colistin sulfate [1264-72-8]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AP2A2,EP400,APBB2,APOC1,CDK5R1,SCAPER,CAMK2G,PDE4DIP,SDC3,HDAC4,GIT2,JAKMIP2,HP1BP3,DNM2,ATN1,DTNA,ZNF276,ELOVL5,IGSF1,IL6R,MAP4,MITF,MPP2,NOS1,SLC11A2,ODF2,PIK3CD,PLEC,SMIM7,PPP2R2B,PLPPR1,ELOVL2,RAD52,ARHGEF10L,RPS6KA2,SBF1,ZNF821,FAM214B,SPTAN1,IQSEC2,TROVE2,ARHGEF9,VPS13A,KIAA0930,TCF7,PCDHGA10,THRA,LMF1,SYNC,PCBP4,SMIM8,SSPN" Drug 3882_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN2,AMT,APC,APLP1,APOC1,CDK10,ARHGDIG,CDK13,SYNJ2,SCAPER,HIP1R,FADS2,CTIF,DMPK,ATN1,DTNA,DUSP9,PLXNC1,NCALD,EZH1,FYN,C1QL1,GLS,NR3C1,MAP2,BCO1,NPPA,TNPO2,PRKCB,PTHLH,FAM120C,RAB3A,RGS12,RASA3,FBXO11,SLC1A7,FAM214B,BTBD7,ZKSCAN3,LIMCH1,ZCCHC24,SPTAN1,LHPP,PLCB1,KAZN,SMG6,TNS2,TMEM121,THRA,PARD3,VIPR2,RNF170" Drug 5272_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SPARCL1,CDC42BPA,SYNJ2,CALB2,SLC16A4,CDH10,CDH18,FAM189A2,CNTN1,SDC3,SRGAP3,HS3ST2,DTNB,ELAVL2,C3orf18,EPB41,RASGRP2,F5,PTK2B,FHL1,KHDRBS3,ZNF44,GAD2,MYOZ2,SRCAP,ADAMTS13,TJAP1,ITIH2,KCNK2,KCNMA1,SMAD1,GIT1,OMG,CLDN11,CDK18,PFKFB2,SERPINI1,PTPRD,SYNDIG1,SEMA6D,NLGN1,KANSL3,PKNOX2,SLC11A1,BEX1,COLGALT2,SYT11,SYN2,TCF7L2,TLR4,TNS1,TRPM2" Drug 4412_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ALK,BIN1,GAS7,CDK13,ATP2B2,KSR1,BAIAP3,CACNA2D1,SEPT7,CACNA2D2,SULT4A1,CNR1,WHRN,NCOR2,ST18,DBT,ZNF589,KIAA1109,FGFR1,GAB1,LILRA2,GRIK5,IL11RA,KCND3,KCNMA1,MAG,BCO1,NCAM1,CAMKV,CEP41,RALGDS,KLHDC8A,PLPPR3,ASAP3,ST6GAL1,BCAN,SLC2A5,SHANK2,LIMCH1,PEG10,TCF4,PCDHGA1,PCDHA6,SLC35G2,TMEM121,TK2,TNS1,XRCC4,MKRN3,SLC30A3,KCNAB1,MVB12B" Drug 1895_UP Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "C1QTNF1,SEMA6A,LTBP4,SYT13,PPFIA3,PDXK,SLC4A4,N4BP2L1,MPDZ,SYNJ2,ARHGEF7,CAPN3,CD38,TAOK2,CLTB,ABCG2,ARHGEF6,CNTFR,SPOCK2,KLHL3,EPB41L1,RACK1,INPP5K,ARFIP1,GJB1,GLS,GRIA4,IFI16,IL6ST,VWA5A,MITF,GIT1,MX1,MYL3,NCAM1,NPPA,NTRK2,OGG1,FSD1,CNNM2,GAL3ST4,RGS12,ST6GAL1,ZHX3,NXT2,ST5,EXOC7,PIK3R5,TRPM2,TSN,REEP1,PLSCR4" Drug 1235_DN genistein; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NME5,MRTFA,APP,MTMR2,CA12,QKI,HOMER3,ABI3BP,CNTNAP2,TOX,LYPD1,PARD6A,G3BP2,MED12,FEM1B,EFNA3,EPB41L1,DMTN,SPEG,DLC1,CHST15,FGFR1,TRMO,CGREF1,SYNPO,KHK,MEF2C,SCAMP5,NDP,CNOT4,PTPA,PTHLH,PTPRN2,ZDHHC14,RGS4,CSRNP3,SCG5,ASAP3,DOCK10,AMBRA1,SLC1A3,ARFGAP1,LIMCH1,PDZD2,SPTAN1,SPART,METTL3,TRIO,TSC2,SSBP2,TRIM9,SENP7" Drug 6603_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADD1,C1QTNF1,ADGRF5,ALK,SEMA7A,DDO,CDC14B,BRINP2,RASL11B,ATP2B3,ATP6V0A1,CACNA1I,CACNB2,TAOK2,RGS6,VCAN,CTIF,DLG4,DTNA,EDIL3,EDNRA,EDNRB,FGF1,TRAF3IP2,GNAO1,GPD1,PRUNE2,GUCY1A2,KCNB1,LAMA2,MATK,KITLG,NF1,PFKFB4,PPP1R1A,PRKAR1B,C1orf54,RGS12,KLHL11,KCNIP1,IL17RB,ASAP3,NTNG1,SLC2A5,SCN3B,SAMSN1,NACAD,COBL,THRA,TIMP4,LAT2,PARP6" Drug 6743_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,AGT,APAF1,SLC4A4,N4BP2L1,SCAPER,RUNX1T1,CD86,MAGI1,DLGAP1,HOMER3,SPOCK2,DUSP9,EDN1,SGK2,HIPK3,ING4,ETV1,AGAP2,NSG1,HBS1L,PRUNE2,CNTRL,GRM7,ELOVL5,VWA5A,MMP16,ADAM22,TAGLN3,NF1,NNAT,PDE4B,GPR85,PFKFB4,RETREG1,PTAFR,ELOVL2,TMEM231,FAT4,RASGRF1,RGS3,IL17RB,ZFP30,SLC1A7,OGDHL,TNIK,HECW1,TACR1,DAAM2,CABIN1,EMSY,KCNAB1" Drug 7327_UP Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NDRG3,AK2,KIF1A,RAB29,CACNA1D,CHN2,PLEKHB1,B4GALT6,FADS2,COL9A2,NCOR2,MFAP3L,EIF5,ING4,CAMSAP1,FOXG1,FYB1,HBS1L,SIGLEC8,RND1,LPAR4,CACFD1,NR3C1,INPP1,ITIH2,KCNK2,MGAT3,MMP16,MSI1,LYRM9,NF1,CNOT4,NOVA2,SERPINE2,NLE1,SAMD9,ZSCAN32,RGS12,SBF1,ASAP3,BCAN,ABLIM3,SMARCD3,RBM34,TSNAXIP1,ERC1,TROVE2,MAPK8IP3,ACSBG1,DOCK9,THRA,EVI5" Drug 2479_UP Tiabendazole [148-79-8]; Up 200; 19.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN2,ADD2,SRPX,AMH,AMPH,CDC42BPA,CDK10,DNAH17,BMP7,CHN2,CHRNA4,CLU,SULT4A1,CREM,ABCG1,RIMS2,PHYHIP,DNAJC6,EDNRA,RRAGB,KIAA1109,STON1,GPR22,RAPGEF1,ADAMTS6,RASSF8,ITPKA,MAPT,MDM4,NAP1L2,NPR2,CLDN11,PFKFB4,PPP2R2B,GDPD2,PTPRO,TTLL7,KLHDC8A,NEK11,TCP11L1,SLC1A3,SLN,PALLD,SOX10,ARHGAP26,ATP10B,CHST5,UGT8,VGF,VSNL1,PRDM10,SLC17A7" Drug 5672_UP Tyloxapol [25301-02-4]; Up 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BEGAIN,CDK13,RGS11,MTMR7,DCLK1,DLGAP2,DLGAP1,AKAP6,NCOR2,AATK,BRINP1,DBN1,SRGAP3,EGFR,NRN1,PTK2B,FYB1,SIGLEC8,ATP8A2,GNAL,LPAR4,MCHR1,GRIK1,GRIK5,GRM8,GSN,ITIH2,KCNJ5,KCNMA1,LAMA2,MEF2C,PDE4D,PDGFRA,PMP2,PKN2,GDPD2,RAB3IL1,RNASE1,TCP11L1,SYNDIG1,ARHGEF40,SLN,RBM34,MYT1L,SOX10,IQSEC2,SAMSN1,SYT11,TCF4,TRIM2,R3HDM1,PARP11" Drug 5483_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AGT,NR0B1,LTBP4,BIN1,FAM131A,DDX3Y,CFLAR,LHX2,CRYM,NOS1AP,DGKG,C2CD2L,ELAVL4,HSD17B14,PTK2B,ATP8A1,ZNF589,BAIAP2,AGAP2,PRELID3A,GAB1,SRCAP,MALT1,HLF,INPP5B,KHK,MEF2C,CNOT4,NTRK2,MTRF1L,PPP2R2B,PRKCB,GDPD2,PTHLH,ZKSCAN3,WDTC1,KIF21B,EMC1,HECW1,TROVE2,COLGALT2,SMG6,PSD3,CRTC1,DAAM2,RIMBP2,PIK3R5,SEZ6L,VIPR2,LAT2,NAV2,ITM2C" Drug 5739_UP Cytisine (-) [485-35-8]; Up 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BEGAIN,TRMT9B,APC,N4BP2L1,BMPR1B,CBS,CDH8,CHI3L2,PLEKHB1,CLCN4,RAB26,HOMER3,CRMP1,NCOR2,ABCG1,DAPK3,SPOCK2,AK5,EXOG,ST8SIA3,HIPK3,EFNA3,MTSS1L,ZNF549,KIAA1109,FOXG1,TBR1,SIGLEC8,SYT17,CPLX2,RND1,GNAO1,GPM6A,LPAR4,ATXN2L,IL6ST,JAK2,PDE3B,PDE4D,PDGFRA,PPP2R2B,ZCWPW1,NEK11,SLC4A3,ZSWIM8,MCF2L,DOCK9,CRB1,R3HDM1,AMACR,RPRM,KCNAB1" Drug 7357_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "PLA2G6,MRTFA,DOC2A,LGR5,SLC4A4,SLC2A11,LDLRAD4,CAMK2B,USP2,SLC16A4,ARHGEF2,CLU,HOMER3,COL9A3,FAM169A,SPOCK3,DTNA,EDNRB,ING4,SRPK3,FOXG1,DPYSL4,ZNF44,GNAS,TDRKH,GRM8,ATXN2L,ELOVL5,MAP4,ADAM22,MSR1,NEUROD1,NF1,SETD4,SLC25A23,RIPOR1,RGS12,FBXW7,SBF1,ZNF821,SH3BP2,CNKSR2,ZCCHC24,RAP1GAP2,MAPK8IP3,RGL1,PHLDB1,VAMP1,RALYL,DICER1,TRPC1,FAM13C" Drug 5102_UP Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "APC,GAS7,PRX,DNAH17,ADAM23,CACNB2,MAP7,RUNX1T1,FOXN3,STOML1,DNAJB5,HOMER3,MICAL2,VCAN,PYGO1,CHRDL1,DTNA,TOM1,AASS,ING4,MRNIP,CEND1,HPCAL4,GAD1,GPR19,ICA1,ITIH2,NDUFA5,NF1,NPTX1,NTRK2,EPN1,SYTL2,PTPRH,FAM120C,MYH14,SYNDIG1,FOXRED2,IL17RB,FRMPD1,KANSL3,SPTB,ATP10B,MAPK8IP3,COBL,TMOD1,PIK3R5,TPM2,RUNDC3B,TMPRSS5,NSD2,EPM2A" Drug 4986_DN Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADORA2A,ADRA1D,KIDINS220,ALCAM,BIN1,AMT,APC,APOC1,BCAS1,APP,CDC14B,PLA2G4C,BTRC,CACNA1D,CDH10,ARMC8,CNTNAP2,TBC1D5,DAPK3,C2CD2L,MAGI2,DRD1,DTNA,EFNA3,SCML2,DLC1,GPD2,TDRKH,GRB10,VWA5A,MSI1,N6AMT1,NEK1,NPR2,PLCD1,PLXNB1,MBOAT7,ZDHHC14,GSTCD,ASAP3,LIMCH1,ZHX3,TSPYL2,NXT2,ATP11A,TK2,TMOD1,FAM155A,VAV2,VLDLR,ZNF24,PHTF2" Drug 6716_UP Glycocholic acid [475-31-0]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "DPF1,ASIC2,ADCY2,ADORA2A,BEGAIN,AMPH,AQP4,N4BP2L1,BACH1,RGS11,RUNX1T1,CD86,CACNA2D2,IPCEF1,PHF14,DAPK3,DSCAM,DYRK1A,RASGRP2,EFS,CORO2B,FGFR1,HPCAL4,SRCAP,GRIK5,SOX21,PTGDR2,MAG,MAPT,NPR2,PDE4B,SPATA6,PPP1R1A,ZFP30,PKNOX2,CXXC4,IZUMO4,HECW1,SPTB,RAP1GAP2,ARC,TACR1,ADGRL3,PCDHGA10,PCDHA5,TIMP4,TPM1,VIPR2,VLDLR,REEP1,NLRP3,GAN" Drug 1002_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,NDRG2,AK2,CDK13,ASPH,ATP2A2,CAMK2G,TAOK2,SLC4A8,ARHGEF10,PDE4DIP,DAPK3,ARMCX2,RABGAP1L,ATN1,HIPK3,EFNB3,VPS26C,ZNF589,DPYSL4,CAMKK2,GAD1,HBS1L,B4GALNT1,DISC1,GLYR1,HSF2,LSS,MATK,LYRM9,ZNF862,NF1,OGG1,SLC25A23,RAB3IL1,FAM184A,RGS3,ANKRD6,KANSL3,LIMCH1,KDM4C,ZBTB43,THSD1,DIP2A,VAMP1,VPS13A,PLCB1,ARHGEF12,UPF3A,PRDM2,GDPD5,PHTF2" Drug 1296_UP Androsterone [53-41-8]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABHD6,NDRG3,MTUS1,APOC1,CDK10,SLC4A4,BTRC,CFAP410,HIP1R,INA,DGKI,IQCK,SIPA1L1,PDE4DIP,SV2A,SGSM2,EIF1,IQCG,FLT1,SRCAP,GPR19,INPP5B,LSS,N6AMT1,ZNF862,SLCO1C1,NFYA,NUMA1,PDE4B,PRKAB2,MAPK8,PTAFR,PTN,ZNF493,SEC14L1,FNDC3A,SLC9A5,ZNF423,SPTB,SS18,STXBP1,ADGRL3,SMG6,SIN3B,PSD3,ATP13A2,TIAM1,KCTD2,TNS1,SMUG1,PDSS2,EPM2A" Drug 2116_DN Ethosuximide [77-67-8]; Down 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADD1,APBB2,APP,ARRB2,MAP7,LHX2,QKI,SLC4A7,DBT,HP1BP3,FEM1B,EFNA3,EPB41L1,VPS26C,WAC,ZNF589,FHL1,GART,GNAS,AGFG1,NACA,NASP,NUCB1,PFKFB2,PIK3R1,MBOAT7,SAMD9,ZDHHC14,MCMBP,SUPT20H,SLC20A2,SLC22A4,TAB2,SS18,ST5,SYNE2,COBL,CAMSAP2,FBXW11,EHBP1,TRIM2,ARHGEF12,TRPC1,NSD2,WNT7A,NDRG4,LRP8,FIP1L1,MPPE1,PDSS2,PHTF2,RNF146" Drug 3665_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AMH,APC,GAS7,PRX,ASCL1,ADAM23,BMP7,SYNJ2,BAIAP3,NEURL1,CHI3L2,NRXN2,TPP1,COL9A3,HAPLN1,MFAP3L,ATN1,DTNB,DYRK1A,LRRC17,CACNG3,AFF2,IQGAP2,GAP43,GPD2,PTGDR2,HSF2,LYRM9,MYT1,NCAM1,NTRK3,OMG,FXYD1,PROX1,PTH1R,RFX2,SLITRK3,KDM4B,SCN3B,ZC3H13,ATP10B,MAPK8IP3,SYT11,ACSL6,CUX2,CRTC1,TK2,ICAM5,R3HDM1,PIK3R5,TRPC3,VGF" Drug 3944_DN Sulfachloropyridazine [80-32-0]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NDRG2,AP2A2,APBA2,APLP1,APP,CDC14B,SLC2A11,MTMR3,HAP1,AKAP7,CSNK1E,EDRF1,KIAA0586,CDON,SLC12A6,DRD1,ATN1,EDN1,PLEKHO1,EPB41L2,ERBB2,CEND1,EZH1,FGFR1,FHL1,DLL3,ERAP1,DISC1,GCNT2,SRCAP,MSL3,POLL,KCNN2,KIF5C,NF1,NPY,PFKFB2,PEX5,RAD52,ZDHHC14,RGS12,PAQR6,SEMA6D,SUPT20H,SH3BP2,NLGN1,FAM214B,ZCCHC24,STX1A,POPDC3,PHTF2,ADAMTSL3" Drug 3626_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ALCAM,BIN1,GAS7,PPP4R4,RASL11B,ATP6V0A1,SYNJ2,BAIAP3,NEURL1,CDH10,CLGN,TAOK2,CLU,FADS2,CNTN1,GIT2,DBN1,CEND1,ZNF589,ZNF276,POLL,GSN,IL6ST,KPNA5,VWA5A,MDM4,MMP17,GIT1,BCO1,LYRM9,NF1,PDE3B,SERPINE2,PLCD1,TMEM104,ZSCAN2,RALGDS,ZFHX4,RXRA,PPP1R9A,FAM214B,SNCA,WDTC1,DOK5,EMC1,THSD1,INKA2,RGL1,TCF7,PCDHA5,THRA,ZMYND8" Drug 3013_DN Propantheline bromide [50-34-0]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NDRG3,PPFIA1,ASPH,AZGP1,SYNJ1,SYNJ2,CACNB4,SLC16A4,CLGN,SOCS6,CHM,B4GALT6,QKI,SIPA1L1,ZNF337,ATN1,HIPK3,SIDT2,MBNL2,PLXNC1,TUBD1,PIPOX,PDLIM5,CAMKK2,OGA,INPP5K,RAB40B,PRUNE2,ELOVL5,KCND3,AFF1,NF1,PPP5C,TMEM231,RAB3A,RAB3IL1,RALGDS,CLIP1,PPM1E,FAM214B,CCDC88A,ZNF415,ATP11A,KAZN,TCF7L2,THBS4,TPM1,TRO,FLRT2,XRCC4,SEMA3B,PCBP4" Drug 6915_UP SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SLC12A5,KIDINS220,PPFIA3,APP,ATM,EIF4G3,SYNJ1,ST3GAL5,SRSF11,RAB28,DNAJB5,QKI,CREM,HDAC4,SACS,TRAPPC9,EGR3,GPR153,FYN,NCKAP1,MALT1,TXNL4A,GLS,KCNH2,OPA1,OXTR,PPP2R5C,PTCH1,ELOVL2,PTPN13,PTPRG,KIF16B,FBXO11,WDR47,MAPKBP1,UHRF1BP1L,KDM4C,ELOVL4,NEK4,FAM168A,SYT1,MTCL1,TCF12,DOCK9,CRTC1,TRPC1,SSBP2,VGF,WRN,MFF,PCBP4,JMJD1C" Drug 2636_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SYN3,ADD2,BEGAIN,AMPD3,APLP1,CDC14B,MARK4,N4BP2L1,NRP2,RUNX1T1,CSF1,CTIF,DCT,AK5,SORBS3,HSD17B14,IGSF6,SPEG,ANKMY1,ACSL4,TUBB4A,ATP8A1,ZNF589,FLNC,SIGLEC8,DISC1,GLYR1,GNAL,NR3C1,MDFI,MEIS2,NOS1,OPRL1,P2RY1,PAH,KCNK10,CDK14,CAMKV,SDK2,PPARA,PTHLH,ZNF493,RGS12,MYH15,SNAP25,IQSEC2,PSD3,HIF3A,ICAM5,HEY2,SEZ6L,VAV2" Drug 5064_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADCY6,ADORA2A,ADRA1B,AMPH,AMT,APBB2,ASCL1,ATP2B2,ADGRB2,NRP2,CFLAR,CAPN3,ENTPD2,CRLF1,ARHGEF4,DAPK3,BRINP1,HEPH,DMPK,ST8SIA3,SIDT2,EFNB3,COQ7,RCAN2,KCNMB2,ETV1,REEP2,CACNG2,EFCAB2,ALDH1L1,GRM8,GUCY1A2,KLF12,KCNF1,MBD1,MDM4,NPTX1,PFKFB4,C19orf57,MINDY2,PRKCB,GRAMD1C,DCHS2,RGS10,SLN,SNCA,SP4,RALYL,TEK,SEZ6L,TUBB1,VGF" Drug 3666_DN Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,MRTFA,CDC42BPA,APAF1,APC,ARRB2,SCAPER,ARHGEF1,CACNA2D2,TAOK2,ARHGAP22,LHX2,NCOR2,SLITRK5,DAPK3,CDON,ATN1,DSCAM,IRAK4,FGF1,OGA,TJAP1,KCNB1,MBD1,SCAMP5,TAGLN3,NFYA,RETREG1,SLC25A23,MAPK7,GON4L,PTPRN2,RAB3IL1,RAD51D,ENOX1,GAL3ST4,GTDC1,RGS10,RXRA,FAM102A,ST6GAL1,IFT122,IQSEC2,SS18,COBL,ASTN2,ROBO3,TRIM2,CHST8,AMACR,ZKSCAN5,NT5M" Drug 1671_UP Meticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "APC,MADD,MARCH3,MARK4,SLC4A4,ADAM15,CFLAR,CFAP410,SOCS6,RAB28,ZFYVE9,TPP1,SH2B1,ARHGEF4,MFAP3L,RUSC2,CDON,EFNA3,VPS13B,DMTN,NCALD,DLC1,IQCG,GAB1,ALDH1L1,GRB10,NR3C1,ATXN2L,MAP4,MATK,MKLN1,MMP17,MYO9A,NF1,CNOT4,ODF2,PGAM2,PLCD1,POLG,ROM1,ITSN1,SLC1A7,SLC2A5,PPP4R3A,DOK5,ARHGAP26,EXOC7,TCF7L2,TRIM2,TPM1,LMF1,NDRG4" Drug 2802_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NME5,PLA2G6,PLA2G4C,DNAH17,SCAPER,CACNA1I,CACNG1,CCKBR,CACNA2D2,AKAP7,ABI3BP,DCAF4,NOS1AP,KIAA0513,DLG2,TRAPPC9,DYRK1A,MBNL2,TNK2,HSD17B14,C1orf61,AFF2,GAD1,GDF9,GFER,RND1,GNG3,PCLO,WIF1,KCNF1,MAN2A2,MMP16,LYRM9,PALM,PFKFB2,PURG,TNPO2,MAPK8,PRODH,RELN,RPS6KA2,ASAP3,ST6GAL1,SNCA,KDM4B,MAPK8IP3,VAMP1,SPX,CABIN1,UCHL1,UPF3A,DNALI1" Drug 594_DN arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AK2,C1QTNF1,CDC42BPA,ANK3,ASCL1,ALDH4A1,CACNA1I,C5,HAP1,VAX2,SH2B1,HINFP,ECE2,MED12,ATN1,PLEKHA1,EPB41L1,STX2,TMEM8B,SRCAP,ZNF276,GRIK5,MAP4K5,PADI2,ARHGAP19,INPP5B,SMAD1,MMP17,MPP2,NOVA2,OPRL1,PCDH9,MASP1,LRRC49,RIPOR1,RLBP1,SEMA6D,ZNF821,ITSN1,SLC11A1,ELMO2,SMARCA4,TMCC1,KDM4B,ZSWIM8,ATP13A2,TIAM1,KCTD2,ZKSCAN5,ZNF45,ZNF74,MPPE1" Drug 2220_UP Nicergoline; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASIC1,NME5,ALCAM,MRTFA,ATP1A3,ATP2A2,ATP2B2,ALDH7A1,SYNJ1,ST3GAL5,CAMK2B,ADGRG1,ASIC3,CHRNA4,COL9A3,SLC4A7,RIMS3,JAKMIP2,HSD17B14,RASGRP2,SPEG,PTK2B,KIAA1109,SORBS1,TBR1,FYN,GABRA2,TRAF3IP2,GNG3,GPD1,ICA1,IL6ST,ITGA7,CD200,NF1,NTRK2,PFKFB2,PACSIN1,MAPK7,SAMD9,PTAFR,SEMA6D,SH3BP2,FRMPD1,ASAP3,BCAN,IZUMO4,PEG10,KAZN,CLIP2,KAT6A,DPF3" Drug 1222_UP 2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "MTUS1,AK2,APC,APOC1,PPFIA3,CDK13,STX16,CFAP410,CNOT8,RAB33A,NCOR2,EDRF1,GPRASP1,ARMCX2,SV2B,CDON,EDNRB,SGK2,CNNM1,FECH,FOXG1,OGA,ALDH1L1,GSN,ICA1,VWA5A,MIA2,MN1,MX1,ZNF862,NELL2,P2RY1,PDGFRA,PENK,SERPINI1,RETREG1,FXYD1,SPATA6,MAPK3,PTN,PEX5,CCDC40,RGS4,TCP11L1,SUPT20H,BTBD7,SLCO1A2,SNCA,SPTAN1,SYT5,TPM3,EPM2A" Drug 1690_UP Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADGRB2,CFLAR,MTMR3,CACNA1I,CACNA1D,CRLF1,DNAJB5,PICK1,SH2B1,JAKMIP2,MFAP3L,RCAN1,EDNRA,EDNRB,EFNA3,ZIC4,DCTN2,HBS1L,DISC1,SRCAP,GNG4,GRB10,NR3C1,NXPH3,KLF12,JAK2,MAN2A2,MBD1,KITLG,ADAM22,ZNF862,NACA,NFYA,CNOT4,NPR2,SNTG1,CDK18,MBOAT7,PPP5C,PLPPR1,NKAIN1,TCP11L1,SUPT20H,FNDC3A,EMC1,KDM4C,PLCB1,EXOC7,VIPR2,ZIC3,ST7,GAN" Drug 2878_UP Iobenguane sulfate; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ALCAM,BIN1,APC,PLA2G4C,ATM,ATP2A2,SCAPER,BAIAP3,ADGRG1,CHM,FADS2,SDC3,RIMS2,EDRF1,ARHGAP24,RASSF2,SRGAP3,ATN1,ERCC2,EFCAB2,FAM49B,RASL10A,SRCAP,RND1,GRIK5,ATXN2L,ICA1,KIT,MEF2C,MOBP,MX1,NDUFA5,NF1,CDK14,LRP12,PACSIN1,RAD52,C1orf54,ZMAT4,MYH14,ARHGEF40,LIMCH1,EMC1,SPP1,TBCEL,DMXL2,SZT2,PSD3,SLC44A1,WBP2,FAM155A,VAV2" Drug 5788_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SERPINA3,ASIC1,ARID1A,ADCYAP1R1,NME5,DDO,LGR5,CADM3,CACNB2,ARHGAP33,NRXN3,PICK1,AKAP5,ENTPD4,EDNRB,KCNMB2,CEND1,KAT8,FGF1,HPCAL4,C1orf61,PRELID3A,FYB1,GABRA2,GABRA5,GRM2,GSTM5,ATXN2L,KLF12,HPSE2,KCNA2,KCNB1,KCNH2,KCNJ5,OLR1,PDE4D,PFKFB4,PIK3CD,LRRN3,PTCH1,CCDC40,ENOX1,BCAN,SLC11A1,TACR1,SMG6,TEX15,THRA,RUNDC3B,TRPC3,VAV1,REEP1" Drug 5944_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "DPF1,AP2A2,CDC14B,ARNTL,NUMB,RASL11B,ALDH7A1,CACNA1I,CAMK2B,USP2,CDH18,CLGN,SULT4A1,CABP1,PLCH2,TMCC2,CDON,ATN1,RCAN1,C3orf18,RRAGB,CEND1,DLC1,FGFR1,PDLIM5,GNAL,GRM7,HLF,IRF8,INPP5B,KCNH2,PACRG,CD200,NUMA1,SERPINE2,PLEC,POU3F2,MAPK7,PTPRH,PTPRO,SALL1,SCG5,MAPK8IP3,PHLDB1,PLCB1,ADGRL3,TRIM2,TRPM2,NSD2,ZIC3,KAT6A,TIGD6" Drug 6197_DN "ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADD2,BIN1,APAF1,ASPH,ALDH4A1,KIF1A,BMP7,LDLRAD4,CFAP410,SLC25A14,HIP1R,ARHGEF1,CBFA2T2,REPS2,TAOK2,NMT2,COL9A2,CREM,FEZ1,PDE4DIP,CTNND1,CTIF,ST8SIA3,HIPK3,F5,FOXG1,FYB1,GPD2,CACFD1,ELOVL5,AGBL5,VWA5A,ZNF862,SLC11A2,MAPK8,WDR25,FAM120C,RAB3IL1,RGS3,MRAS,EPN2,ARHGEF40,KDM4B,WWC1,TBCEL,SIN3B,PSD3,RBFOX2,VIPR2,WNK1,PCBP4,NLRP3" Drug 6762_UP Cefotiam hydrochloride; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADD2,ADRA1D,AP2A2,C1QTNF3,BEGAIN,AMT,ANK1,PPP4R4,SLC4A4,CFAP410,TAOK2,FAM131B,DCT,PLPPR4,DTNA,DUSP9,FGF1,LILRB4,PRUNE2,KLF12,KCNB1,VWA5A,TM6SF1,LYRM9,NF1,NTRK2,PCDH9,PFKFB2,RETREG1,PLP1,POU6F1,PPP5C,GDPD2,PTH1R,KLHL11,KCNIP2,RASA3,FBXO11,PREX2,SLC11A1,HECW1,COBL,TAL1,PCDHGA10,TK2,LILRA4,HIRA,TFIP11,EMSY,KCNAB1,EPM2A,DPF3" Drug 6202_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN2,ARID1A,OGT,CDC42BPA,PPFIA4,CNTNAP1,APBB2,SLC4A4,CACNG1,CALB2,CH25H,CHRNA4,DNAJB5,CSNK1E,PDE4DIP,FAM169A,PLPPR4,TMCC2,HS3ST2,ELAVL3,MRNIP,ARMCX1,FHL1,C1orf61,GPR162,GRM2,PRDM5,KIF3A,KCNK1,MMP16,MOBP,MSI1,MX1,NPPA,PCDHGC3,CNNM2,MARCH1,RASGRF1,SLC6A11,FAIM2,TNIK,ZHX3,LHPP,MAPK8IP3,ATP13A2,GPR161,ICAM5,SEZ6L,UBE3A,SLC26A10,ST7,NUP214" Drug 5437_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SLC12A5,ADRA1D,AK2,SRPX,EPB41L5,ARHGDIG,MARK4,ATM,BAIAP3,PLEKHB1,NMT2,ARHGEF6,AKAP7,C2CD2,SDC3,TBC1D5,NCALD,ANKMY1,FGFR1,SEMA4D,INPP5K,MSL3,GPER1,IL6ST,KCNJ3,KHK,KPNA5,MITF,ADAM22,CNOT4,PDE3B,NLE1,TMEM104,PTHLH,RAD52,EMID1,PPP4R3A,ZNF430,SLC20A2,NSFL1C,VPS13A,ASTN2,EXOC7,IQCE,RPGRIP1L,CHST8,HIRA,UBE3A,KCNK12,ZBTB14,SPHK2,GDPD5" Drug 3533_UP Procarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "PLA2G6,SEMA4G,CDK13,CADM3,CFLAR,CAST,ARHGEF2,ARHGAP33,FOXN3,ASIC3,TAOK2,SLIT2,IPCEF1,ST8SIA3,SGK2,AASS,FABP7,ZNF44,ERAP1,SIGLEC8,INPP5K,GATM,GRM1,CELF3,KCNN2,AFDN,ADAM22,SLCO1C1,NKX2-2,NPY,PDE3B,ENPP2,PENK,PNMA3,PACSIN1,RAB3IL1,C1orf54,RGS4,RLBP1,MRAS,RPH3A,SLCO1A2,MAST1,SMARCD3,LIMCH1,DOK5,SAMSN1,PSD3,THBS4,HEY2,TRPC3,LAT2" Drug 6651_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SYN3,SPARCL1,ANK2,RASL11B,AZGP1,RGS11,CAPN3,CRLF1,EPS15L1,VAX2,SLC4A8,NCOR2,PLCH2,CNTNAP2,RIMS2,MFAP3L,DMPK,DUSP9,EDNRB,TNK2,ELN,OLFM1,CAMSAP1,SORBS1,PRELID3A,CACFD1,ATXN2L,ITGA7,KCNC1,MAG,MMP16,NEFM,NOVA2,NTRK2,OPCML,PDE4B,PTPRD,RGS12,PNMA8A,FRMPD1,DOCK10,NTNG1,SLC6A9,KIF21B,PHLDB1,TPM1,TRIO,BEST1,PRDM2,SLC17A7,NUP214,DPF3" Drug 5013_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NME5,CDK10,ARRB1,SLC4A4,CFLAR,SYNJ2,CA12,CLU,AKAP7,ABCG1,DZIP3,RIMS2,SEZ6L2,EFNA3,EML1,PRELID3A,INPP5K,SRCAP,RAB30,GNG4,PCLO,ARHGAP19,AGBL5,INPP5B,KCNF1,LMO2,MAPT,TM6SF1,MSI1,ZNF862,PDE3B,PLEC,RAD51D,RGS10,WLS,CPEB3,EPN2,SMTN,FAM214B,LIMCH1,FNBP1,CLSTN2,SEMA4A,MCF2L,TCF7L2,PSD3,OBSL1,NSD1,CRTC1,CABIN1,GDPD5,EPM2A" Drug 3023_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN2,KIDINS220,MTUS1,ANK3,APAF1,ADAM15,FUBP1,CACNB4,ZFYVE9,TPP1,FAM149A,CHD5,ARHGEF4,RUBCN,BRINP1,B3GAT3,KIAA0753,VPS13B,CAMSAP1,AGAP2,TBR1,GAB1,ADAM28,GNG3,GNG4,LILRA2,PADI2,ATXN2L,TJAP1,KCNJ5,MAP4,TAGLN3,NCAM1,NLE1,POU6F1,PRKCZ,PTCH1,TMEM231,RAD52,GALNT10,ANKRD6,EPN2,CCDC88A,ZNF415,ZCCHC24,TCF7L2,PCDHGB6,AHCYL2,TPM1,CDK20,KCNK12,SH3GLB2" Drug 3402_DN Primidone [125-33-7]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NDRG2,LTBP4,AMPD3,BIN1,APBA2,APLP1,SYNJ2,SLC16A4,CLGN,ADGRG1,WHRN,SH2B1,NCOR2,SGSM2,DMPK,DRD1,EDNRA,EIF4G2,ING4,ELN,SPEG,ZNF589,CAMSAP1,PDLIM5,SRCAP,ELOVL5,KCNH2,KHK,VWA5A,MAPT,MMP16,MOBP,PALM,CDK14,SERPINE2,MED1,MINDY2,PPP5C,MAPK10,RAD52,EMID1,PEX26,SNCA,IQSEC2,SPART,THSD1,VAMP1,PLCB1,POPDC3,SMG6,KCTD2,REEP1" Drug 3472_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABR,SLC12A5,PPFIA3,ALDH4A1,ATP6V0A1,PLAA,TPP1,ARMC8,EDRF1,DTNA,EDNRA,SIDT2,FAM198B,KAT8,BAIAP2,SYT17,INPP5K,GLYR1,GLUL,CNTRL,DHX35,INPP5B,MIA2,KITLG,MPP2,PBX1,RETREG2,PTCH1,RAD51D,MYH14,ROM1,SBF1,ATXN1,GALNT10,ITSN1,AMBRA1,SMTN,ELMO2,DOP1A,TSPYL2,SEMA4A,IQCE,TCF7L2,TRIM2,BEX4,PARD3,RBFOX2,VAV2,KCNK12,ZNF74,MPPE1,NUP214" Drug 3198_DN Chlorthalidone [77-36-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADCY6,ADRA1D,AK2,TRMT9B,APBB2,ASPH,RASL11B,SLC4A4,KIF1A,SOCS6,CLU,SLC4A7,SH2B1,CSF1R,FAM169A,CYBB,CTIF,RABGAP1L,DTNA,EDNRA,EIF5,ELAVL3,FGFR1,FHL1,ANKFY1,GABRG2,ERAP1,MSL3,HNMT,IL6R,ITPKB,MINDY2,RELN,RAD51D,RALGDS,RGS10,RGS12,GSTCD,RPS6KA2,RASA3,COA1,KIF13A,ACSBG1,VAMP1,DOCK9,SLC44A1,PARD3,RUNDC3B,TRPC1,ZMYND8,ZNF74,EPM2A" Drug 4233_UP Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ACTN2,GAS7,CDK13,MARK4,CDK5R2,CAMK2B,ARHGAP33,CNTFR,EDRF1,MAML1,SPOCK2,DCC,SRGAP3,DLG4,EDN3,EDNRA,EFS,ABCA8,HBS1L,GATM,TOX3,SOX21,TJAP1,ITIH2,KCNC1,KCND3,MMP16,NOS1,NPTX1,NUMA1,OLR1,SERPINI1,MAPK8,MAPK10,CNNM2,PTPRH,GAL3ST4,ZMAT4,RGS3,RTN1,CNKSR2,SLC12A4,DDN,ASTN2,MCF2L,DICER1,TMOD1,TNS1,NPL,TUBB1,MVB12B,DPF3" Drug 5765_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NME5,ADGRF5,KIF1A,ADGRB1,CACNA1I,BTRC,CA8,SYNGR3,LY86,CNR1,CSF1,FEZ1,ARMCX2,ATN1,DSCAM,ECM2,DYRK1A,EDIL3,EDNRA,CNNM1,TNK2,EN2,RCAN2,NCALD,ETV1,EZH1,F5,DLC1,OLFM1,HPCAL4,AFF2,DCTN2,FYB1,POLL,GRIA4,GRM7,ITIH2,KCNB1,KCNN1,LSS,MDM4,C1orf54,SYNDIG1,DZIP1,SPTAN1,TMEM151B,ZFPM2,THRA,BHLHB9,DAAM2,WIPF1,SLC17A7" Drug 3504_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ALCAM,TRMT9B,APBB2,DDO,SEMA4G,ALDH4A1,SLC2A11,ADGRB1,LDB2,SCARB1,ARHGAP33,FOXN3,CHN2,CHRNA4,DMD,PLXNC1,OLIG2,LRRC17,MALT1,RND1,GLS,GUCY1A2,ELOVL5,MDM4,MPP2,ADAM22,ZNF862,PDE1C,PDE4D,SMOX,LRP12,POU6F1,MAPK10,DCHS2,FAM120C,C1orf54,KLHDC8A,SLA,PKNOX2,SLC6A9,SNCA,ZCCHC24,ARHGAP26,CDK19,TACR1,PCDHGA10,TNS2,SLC35G2,FAM155A,VGF,WIPF1,NDRG4" Drug 4752_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASIC1,ABHD6,APBA2,CDK13,CCK,CDH2,EPS15L1,TPP1,NCOR2,ARHGEF10,CYBB,SPOCK2,TMCC2,EXOG,ATN1,EDN1,EGR3,ELAVL3,EN2,FGFR1,AGAP2,SIGLEC8,LYVE1,GNG3,KLF12,HPSE2,SYNPO,ICA1,KCND3,KCNH2,VWA5A,SMAD1,MATK,MMP16,MOBP,MPP2,NTRK2,PDE4B,PPARA,MAPK7,RGS12,EMC1,ATP10B,PHLDB1,TACR1,TRIM2,TGFBR3,THRA,LAT2,SLC30A3,EVI5,ITM2C" Drug 3609_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABHD6,BIN1,GAS7,ASPH,ALDH7A1,BMP7,SCAPER,NEURL1,B4GALT6,STOML1,GREB1,DBT,ATN1,FEM1B,FCF1,TUBB4A,ZNF589,FGFR1,PRELID3A,GAD1,MALT1,GNAS,NR3C1,GSN,IL6R,INPP5B,JAK2,KCNJ5,KPNA5,IPO5,TM6SF1,MMP16,ADAM22,RELN,RGS12,KCTD17,MYH14,KCNIP1,BTBD7,COA1,WDTC1,TNIK,EMC1,TBCEL,ZMYND8,ZKSCAN5,PLPPR2,WIPF1,ZFP37,EMSY,URM1,ITM2C" Drug 7024_UP Nimesulide [51803-78-2]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABHD6,MRTFA,BEGAIN,SLC4A4,ATP2A2,SYNJ2,GYG2,SGCE,MYRF,BAIAP3,HAP1,ARHGAP33,CACNA2D2,ASIC3,SLIT2,NECTIN3,CTNND2,KIAA0513,INTS1,MED12,ZNF589,FAM49B,GABRA1,ARPP21,CNTRL,CELF3,ELOVL5,KCNF1,MAP2,KITLG,NF1,ODF2,PDE3B,ENPP2,CNNM2,ROM1,WLS,SBF1,FUZ,SLC22A4,CXXC4,COA1,SNCA,KIF13A,CLASP2,AJAP1,ANKRD12,SF1,NDRG4,SEMA3B,ST7,KAT6A" Drug 6487_UP Nabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "KIDINS220,NR0B1,AK2,MARK4,CCDC181,B3GALT2,CADM3,N4BP2L1,AZGP1,CAMK2B,CAMK2G,CBARP,TPP1,SNCAIP,GREB1,RIMS2,BRINP1,HP1BP3,ATN1,DTNA,MBNL2,EGR3,F5,FAM198B,SCARA3,B3GAT1,FYB1,PCDH17,WIF1,HAS2,HRH3,HPSE2,KCND3,KCNN1,KIF5A,SMAD9,PDE4B,PPP5C,RYR1,SBF1,PKNOX2,SLC6A9,ARHGEF40,SLC11A1,THSD1,PSD3,TLR4,TNS1,SEZ6L,FLRT2,XRCC4,MVB12B" Drug 6080_DN Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,ADCY6,NME5,AK2,APC,ARRB1,ADAM23,CFLAR,MTMR3,ARHGEF1,CBFA2T2,ZFYVE9,FAM189A2,AKAP7,CSF1R,SDC3,MAML1,ZNF804A,RUSC2,C2CD2L,OPTN,NCALD,ZNF589,FGFR1,FOXG1,SYT17,SRCAP,GNAS,GNG4,GRM1,RNFT2,INPP5B,KPNA5,MSI1,ADAM22,PDE4B,RETREG1,MAPK7,TMEM231,RAB3IL1,RAD51D,SEMA6D,PEX26,KIF13A,WDTC1,KDM4C,MAPK8IP3,PHLDB1,PLCB1,TACC1,TRIM2,SSPN" Drug 6296_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,MRTFA,AQP4,ASTN1,KIF1A,HAP1,CBFA2T2,QKI,HOMER3,NOS1AP,RIMS3,KIAA0753,NTM,EFNA3,PLXNC1,DLC1,TESK2,ZNF589,FGF1,FGFR1,SCARA3,USP19,ZNF276,IRF8,KCNJ5,KCNQ3,KIF5A,ADAM22,NUMA1,PFKFB4,GRAMD1C,WDR25,PTCH1,RAB3IL1,RGS10,GSTCD,EMID1,RPS20,IL17RB,ZFP30,SLC1A6,SLC1A7,PEX26,SLC9A5,SNCA,KDM4B,ZHX3,TEX15,CHST8,CABIN1,PIK3R5,PAK5" Drug 2535_DN Streptozotocin [18883-66-4]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASIC1,ADRA1D,MTUS1,AMH,KCNAB2,APC,FAM131A,ADGRB1,BMP7,CDH8,TAOK2,PICK1,SH2B1,PDE4DIP,ARHGEF4,EEF1A2,EFNA3,MBNL2,SORBS3,RASGRP2,MTSS1L,GABRA2,ZNF44,SEPT9,SRCAP,PRUNE2,GPM6B,LILRA2,CACFD1,GUCY1B1,MAPT,AFDN,NNAT,PDE4A,PLCD1,LRRN3,RAB3IL1,KHDRBS2,CCDC92,SLC11A1,CXXC4,MYH15,SNCA,ATP10B,JMJD6,SYT5,TAL1,TNS2,THRA,KCTD2,TRIO,FLRT2" Drug 5486_DN Tridihexethyl chloride; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "C1QTNF3,PPFIA3,DNAH17,ALDH4A1,KIF1A,BCL7A,SCAPER,C5,MAGI1,ZFYVE9,CLU,NIPBL,COL4A5,AKAP12,MICAL2,CTNND2,DCAF8,KIAA0586,GIT2,DLG3,ATN1,RCAN1,EDNRA,COQ7,SCML2,DLC1,FHL1,FAM49B,FYN,KLF12,ITPKB,MAPT,MITF,LYRM9,OXTR,PDE4A,LRP12,SUSD4,BSDC1,FOXRED2,SGK1,SH3BP2,FAM214B,ELMO2,POPDC3,TACC1,FBXW11,KCTD2,CABIN1,ZNF384,PLPPR2,TIGD6" Drug 2528_DN Sulfaquinoxaline sodium salt [967-80-6]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADRA1D,NCOA1,SLC4A4,ATP2A2,KIF1A,C5,LDLRAD4,CFAP410,CAMK2G,CAST,CDH8,CDH10,HOMER3,RCHY1,ZNF337,SPATA2,CDON,EFNA3,FAM13A,PLXNC1,LPAR6,PRKAG2,GAA,GABRA2,SEPT9,LILRB4,SLC2A6,TJAP1,LIG4,ZNF862,MYT1,NF1,NFYA,NNAT,PDE4A,LRRN3,RAB3A,RAD52,SUPT20H,FRMPD1,SNCA,RBM26,FCHO1,CEP68,JMJD6,EXOC7,SIN3B,TNS2,TMOD1,TPD52,TPM1,ST7" Drug 2983_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,ADD2,GRAMD1B,ADORA1,OGT,BMP7,CLCN4,QKI,CNN3,SLC4A8,NCOR2,ABCG1,SNPH,DNAJC6,MFAP3L,KLHL3,HIPK3,CNNM1,ING4,FGFR3,ATXN2L,HTR2A,KIFC3,MYCN,TREM2,PFKFB4,PLCL1,MAPK10,PTPN13,PTPRG,RFX2,NUDT11,NEK11,SLC1A7,PREX2,SLC11A1,SNCA,DOP1A,IZUMO4,PEG10,CDK19,ARC,ATP13A2,TK2,TPM3,TRPS1,SSBP2,UGT8,VSNL1,ZNF225,KCNAB1,ADAMTSL3" Drug 1402_UP Ampyrone [83-07-8]; Up 200; 19.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AP1B1,PLA2G6,AMPD3,PRX,PDE8B,ADGRB2,CA12,CACNA1A,CALB2,CNTFR,SH2B1,TMCC2,DPH1,ATN1,EFNB3,SORBS3,SRPK3,ELN,C1orf61,EFCAB2,GAP43,CACFD1,KCNF1,LAMA2,GIT1,SAMD14,NTRK2,PFKFB2,DUSP26,CAMKV,PACSIN1,PPARA,PPP5C,PTN,PTPRN,PTX3,RNASE1,PLPPR3,RXRA,LIMS2,SLC6A11,ZKSCAN3,SNAP25,TNIK,ZHX3,SPTB,PLCB1,LILRA4,ZMYND8,VGF,VIPR2,NUP214" Drug 3839_DN Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ABHD6,NDRG2,ARRB1,SYNJ1,CA12,ARHGAP33,FOXN3,CHM,TAOK2,HOMER3,CSF1,LRIG1,DAPK3,LYPD1,DTNA,DUSP9,MBNL2,ELN,HSD17B14,COQ7,LRRC23,FAM198B,FOXG1,GFER,GLYR1,HTATSF1,LSS,ADAM22,NFYA,NPR2,NUMA1,RETREG1,MAPK8,SNRK,RGS3,RGS10,TCP11L1,WLS,SEC14L1,SH3BP2,FNDC3A,SHANK2,SMARCA4,WDTC1,SOX3,TROVE2,NXT2,TCF7L2,PARD3,MAP3K12,HPS4,SNX27" Drug 5114_DN Bethanechol chloride [590-63-6]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,AMT,ANK3,APC,APP,ADGRB2,CFLAR,ZFYVE9,CLCN4,TPP1,DNAJB5,CSF1R,VCAN,SNPH,BRINP1,PARD6A,SPOCK3,EDNRA,EGFR,MBNL2,IRAK4,ETV1,ZNF589,PNMA2,B4GALNT1,C1QL1,MSL3,DIPK1A,KCNN1,LSS,MAPT,TAGLN3,NFYA,P2RY1,PIK3R1,BCAS3,RAB3A,RAD51D,FAM184A,RGS4,SUGCT,FUZ,SNCA,RBM34,NXT2,SEPT8,KIAA1107,TCF4,SLC44A1,VGF,SH3GLB2,ZNF225" Drug 3004_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,AQP4,ASCL1,MYRF,HAP1,KRIT1,CDH10,QKI,HOMER3,CRMP1,NCOR2,SIPA1L1,PDE4DIP,HIPK3,EIF1,OLIG2,OLFM1,FHL1,DPYSL4,PDLIM5,GAD2,GPD2,ATF7,LILRA2,GRIK1,GRM1,IL6ST,KHK,KIF5C,SMAD1,NCAM1,CNOT4,NUCB1,CCSER2,STRN3,PRKAR1B,DCHS2,ZSCAN32,PTPRN2,NEK11,SLC1A3,SLC1A7,PEX26,SNCA,CDK19,SYN2,KCTD2,TPM3,TRPS1,SSBP2,WNK1,KCNAB1" Drug 6594_DN 5194442; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "NME5,MRTFA,ANK3,APBB2,EIF4G3,CDC42,DNAJB5,QKI,RAB26,TENM4,SLITRK5,FAM131B,DNAJC6,SMG7,DLG3,DYNC1I1,ST3GAL6,CINP,GART,MSL3,GPD2,AGFG1,DHX35,IFI16,SHISAL1,INPP5B,MAPT,NACA,PLEC,SLC25A23,PPP5C,GRAMD1C,BCAS3,WDR25,PTPRN2,PTX3,GAL3ST4,NEK11,RPS6KA2,AMBRA1,LIMS2,KDM4D,BTBD7,PHLDB1,TCF4,OBSL1,BEX4,TNS1,RBFOX2,CHST5,CADM1,XRCC4" Drug 5405_DN Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,SLC12A5,APC,APLP1,BRINP2,ALDH7A1,CACNB2,ADGRG1,SLIT2,SH2B1,PPP6R2,EDRF1,GIT2,ZNF804A,MFAP3L,RABGAP1L,ACSL4,SYT17,AHDC1,RUNDC3A,MSL3,TDRKH,ATXN2L,ELOVL5,MAP4,MPP2,NF1,PCDH9,PLXNB1,MINDY2,MAPK7,RAB3A,RAB3IL1,RGS12,NEK11,RPS6KA2,PAQR6,SBF1,SLC1A7,EPN2,LIMCH1,UNC5B,ST5,MCF2L,TCF7,CRTC1,SLC44A1,TK2,RUNDC3B,VLDLR,EVI5,GDPD5" Drug 7475_UP Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADORA1,BTRC,CACNA1A,HAP1,CAMK2B,CDH10,CRY2,TBC1D5,DBN1,DNM1,DRP2,DTNA,EFNB3,EN2,ENO2,ERCC2,FOXG1,C1orf61,DPYSL4,PRELID3A,GABRA2,DISC1,MALT1,GNAS,ELOVL5,MDM4,ADAM22,NF1,NPTX1,NUMA1,PDE1C,PLXNB1,WDR25,PTCH1,PTPRN2,RIPOR1,KCTD17,GSTCD,ROM1,SEC14L1,SH3GL3,ASAP3,SNCA,ZHX3,VPS13A,COBL,ASTN2,EXOC7,KCTD2,TPM3,SPHK2,SCG2" Drug 6216_UP Trioxsalen [3902-71-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADCY6,DNAH17,MARK4,ATM,BAIAP3,BTRC,CACNA1A,ZFYVE9,QKI,PICK1,CSF1R,TBC1D5,DBN1,RUSC2,RABGAP1L,OPTN,F5,ZNF589,KIAA1109,ERAP1,GLS,MSL3,GNAS,RNFT2,ACOT7,HNMT,IGF1,KHK,MDM4,MMP16,NPTX1,MAPK7,PRPH,SAMD9,NEK11,KCNIP1,ABLIM3,EPN2,SLC15A2,SOX2,KIF21B,ANKRD12,PCDHGA1,PSD3,PCDHA5,TK2,TRPC1,ZMYND8,MICAL1,SPHK2,MAP3K12,PRDM2" Drug 3764_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,BRAP,ALK,MRTFA,AMPD3,APC,SLC4A4,ADAM23,ARHGAP22,LY86,CREM,HAPLN1,RIMS3,G3BP2,DTNA,EGFR,FGF1,FOXG1,DCTN2,CINP,DENND2A,SEPT9,GPM6B,TDRKH,GPR19,KIF5C,VWA5A,MN1,NF1,CNOT4,RETREG1,CNNM2,SYTL2,WDR25,RAD52,RALGDS,RGS10,TCP11L1,SCN8A,BTBD7,SNCA,ARHGAP26,ATP10B,ATP11A,TBCEL,GPR161,TIAM1,TNS1,TPM1,CADM1,VLDLR,TRIM9" Drug 3218_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "TKTL1,ADD2,KIAA1324,FAM135A,APAF1,CFLAR,SYNJ1,BTRC,CA4,CACNA1D,HIP1R,RHBDL1,NEURL1,ARHGEF2,CRMP1,PHF14,CYBB,SPOCK2,ARMCX2,EFNB3,ERCC2,FHL1,GABRA1,DISC1,GCNT2,GRIK2,ADAMTS13,GRM1,ITPKB,MATN3,MYCN,CNOT4,PCBP3,CDK18,PLCB2,LRP12,NKAIN1,RASGRF1,RGS4,SALL1,SLA,SLC1A2,EMC1,UNC5B,CDK19,ATP10B,TAC3,DOCK9,TMEM121,UCHL1,CLIP2,NT5M" Drug 2842_DN Tolazamide [1156-19-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SLC12A5,SHROOM2,ARHGDIG,CFAP410,AP4M1,RCHY1,SIPA1L1,KIAA0513,DAPK3,DBN1,EDNRA,EGFR,EIF4G2,LRRC23,SCML2,PRELID3A,CSPG5,SRCAP,MALT1,RAB30,NR3C1,HNMT,MPP2,GIT1,LYRM9,NEK1,SLC11A2,NRGN,MBOAT7,PRPH,ZDHHC14,RGS10,ARHGEF10L,FUZ,FBXO11,EPN2,SMTN,SHANK2,ZKSCAN3,RBM34,WDTC1,ZCCHC24,ZHX3,FCHO1,ARC,ARHGEF12,CRTC1,SLC44A1,KCTD2,PARD3,WNK1,HPS4" Drug 7064_UP 0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AMT,GAS7,SLC4A4,SLC2A11,CACNA1D,CALB2,CBFA2T2,NEURL1,CRLF1,QKI,SLC4A7,CRY2,CTIF,BRINP1,ATN1,EFNB3,HSD17B14,LRRC23,ANKMY1,HBS1L,AHDC1,GLYR1,GLS,FERMT2,GPER1,GRB10,SLC2A6,HSD17B1,KCNH2,MAP2,MPP2,LYRM9,NEK1,NPR2,CDK18,PLCD1,PRRX1,PRPH,TRIM68,RNASEL,RPS6KA2,KDM4B,PHLDB1,ARHGEF9,CHST8,SLC44A1,HEY1,KAT6B,LMF1,REEP1,MAP3K12,SLC17A7" Drug 5829_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,PPFIA3,APP,CAMK2G,CCNT1,ARMC8,WHRN,BAG4,DBT,KLHL3,SIDT2,SORBS3,EIF5,EZH1,ST3GAL6,FECH,CINP,TRAF3IP2,DENND2A,TMEM8B,DISC1,ARFIP1,PRRC2B,INPP5B,MEIS1,PIK3CD,MAPK7,CNNM2,SAMD9,PAQR6,IL17RB,FAM102A,RAB3GAP1,PDZD2,ERC1,SPTAN1,ZBTB43,NXT2,ELOVL4,GSE1,ATP11A,EXOC7,ARHGEF12,TNS2,ATP13A2,TIAM1,TK2,TRIO,TRPC1,LMF1,KLC2,RNF170" Drug 2816_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "KIDINS220,KCNAB2,CDK13,DNAH17,N4BP2L1,CACNB2,CAMK2B,ARHGEF1,RCBTB2,ASIC3,SULT4A1,AKAP7,RCHY1,TCEAL2,RIMS2,DMPK,SHANK1,EDIL3,SORBS3,C3orf18,HSD17B14,C1orf61,KHDRBS3,DLL3,OGA,GAD2,ERAP1,GRB10,GSN,IRAK3,ICA1,INPP5B,KCNN1,MAP4,CD200,GIT1,SLCO1C1,MINDY2,PTPRD,RAB3IL1,C1orf54,RGS4,KCTD17,SLC1A7,PKNOX2,SLN,ZCCHC24,IQSEC2,WSCD1,CA10,PRDM2,PARP11" Drug 3261_DN Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ALCAM,SRPX,APLP1,FAM131A,PPFIA3,CA4,FADS2,SH2B1,CRY2,CSNK1E,PPP6R2,TBC1D5,DAPK3,DBN1,ACOT8,RCAN1,ZNF589,DISC1,INPP5K,ZNF276,POLL,CLASRP,FICD,HNMT,TJAP1,MAP4,NEK1,NPTX1,RAB5B,RALGDS,FAM184A,GTDC1,RGS10,RGS12,RPS6KA2,SBF1,ZNF821,RASA3,EPN2,SMTN,SMARCA4,KDM4C,IQSEC2,RAP1GAP2,LHPP,SEMA4A,EXOC7,USP22,SIK3,SLC44A1,CABIN1,MICAL1" Drug 4611_UP Tyloxapol [25301-02-4]; Up 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BEGAIN,CACNA1G,CACNA2D1,DLGAP1,JAM2,CSF1,MFAP3L,MAGI2,EDN3,SGK2,ZNF589,DOT1L,FYB1,GNAL,GNG4,GPM6A,GPM6B,LILRA2,ICA1,KCNJ5,KCNQ2,LAMA2,NF1,NTRK3,PDE4A,RETREG1,PPP2R2B,SNRK,RERGL,NEK11,SCN2B,SELL,SLC1A6,RPH3A,SLC6A9,SLC9A5,SNCA,SOX3,BEX1,SPTB,DDN,SAMSN1,MLC1,ARC,SEMA4A,PCDHGA10,OBSL1,ICAM5,TUBB1,VGF,KCNK12,GAN" Drug 5915_DN rotenone; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ADORA2A,SEMA6A,TRMT9B,APBB2,ASCL1,BRINP2,SLC4A4,CA12,HAP1,CD86,PLEKHB1,LHX2,NCOR2,CSF1,FAM169A,GPRASP1,RIMS3,RABGAP1L,TNK2,ANKMY1,KAT8,B4GALNT1,SRCAP,GLYR1,GLS,IL6R,KCNMA1,KHK,MID1,MMP17,NFYA,NPR2,PALM,RETREG1,RETREG2,GON4L,PTAFR,ZSCAN2,BSDC1,SLC2A5,ARHGEF40,RBM34,THSD1,STX1A,AJAP1,ARC,TGFBR3,TMOD1,TNS1,SLC30A3,ITM2C,MVB12B" Drug 4356_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "RALGAPA1,ARID1A,APLP1,APP,SLC2A11,ARHGEF7,MTMR3,GYG2,CA4,NEURL1,CDH18,FOXN3,ASIC3,PLEKHB1,B4GALT6,PICK1,CPS1,DMPK,EFNB3,EIF4G2,TNK2,VPS13B,VPS26C,SCARA3,GAD1,GLS,MSL3,SPACA9,MAP4K5,ICA1,KCNN2,KIT,MMP16,NDUFA5,NF1,CNOT4,NLE1,ATG16L1,C1orf54,RGS10,TCP11L1,RASA3,ZCCHC24,ARHGAP26,THSD1,ST5,ATP11A,HEY2,PARD3,MICAL1,EVI5,NUP214" Drug 4001_UP Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ASPHD1,NDRG2,ADD2,MTUS1,PPFIA3,AQP4,PPP4R4,HAP1,CBS,LDB2,CDC42,NRXN3,TPP1,FAM189A2,VAX2,TCEAL2,RIMS2,SRGAP3,DTNA,TENM1,ING4,TNK2,ETV1,PTK2B,DLC1,GAB1,SRCAP,KIFC3,AFF1,MMP16,MSR1,NTRK3,PCDH9,PDE2A,PDE4A,PIK3CD,RETREG1,PTPRN2,RGS12,KCNIP1,ZNF334,ZHX3,CAND2,SPTAN1,EXOC7,TF,TPM1,TRPC1,TUBB1,CADM1,ZNF24,PHTF2" Drug 4659_DN Equilin [474-86-2]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AMT,CDC42BPA,MARK4,ALDH7A1,NRP2,CBFA2T2,FOXN3,TAOK2,CLCN4,ARMC8,CREB5,NCOR2,ARHGEF10,DAPK3,IRAK4,ING4,MRNIP,SPEG,ETV1,ST3GAL6,FGFR1,SORBS1,TMEM8B,SYT17,ZNF276,GLI2,EML4,CNTRL,SHISAL1,MX1,NDP,OPCML,PAK3,PBX1,MAPK7,PID1,CEP97,SH3TC2,ATXN7,FUZ,UNC5B,ARHGAP26,ELOVL4,CEP68,PHLDB1,SYT11,TCF4,CRTC1,CABIN1,XRCC4,SF1,NDRG4" Drug 5434_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "KIAA1324,APBA2,APLP1,PPP4R4,ALDH7A1,ST3GAL5,CAMK2G,TAOK2,CTIF,C2CD2L,DMPK,DRD1,ATN1,EDNRA,EFNB3,CELSR3,EGFR,RASGRP2,SCARA3,AGAP2,SORBS1,TMEM8B,ALDH1L1,ARHGAP19,KCNN1,MAN2A2,MAP2,MAP4,MATN3,MMP16,GIT1,PLTP,CDIP1,PACSIN1,MAPK8,RIPOR1,RPS6KA2,RYR3,ZNF821,RASA3,FAM214B,PDZD2,SOX2,ZCCHC24,KIF21B,ZHX3,IQSEC2,JMJD6,TEX15,TK2,MAP3K12,PLSCR4" Drug 3022_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "ARID1A,ANK3,PDXK,ASPH,ADGRB1,KSR1,SYNJ2,CAMK2G,SCARB1,CLGN,CHGA,SOCS6,CHRNA4,TAOK2,LHX2,RAB33A,ZFYVE9,ABCG2,COL9A3,CPS1,CREM,PDE4DIP,CTNND1,RUBCN,AASS,VPS13B,RASGRP2,DLC1,GABRA2,ADAM28,PRUNE2,GRK4,AP4S1,MAPT,NEUROD1,NUMA1,NLE1,POU6F1,MAP6D1,SEC14L1,SLC1A7,MYH15,SNAP25,ACSBG1,WSCD1,DOCK9,TPM1,TRO,VAV2,KCNK12,SH3GLB2,JPH3" Drug 3074_UP Tyloxapol [25301-02-4]; Up 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "BIN1,ANK2,ANK3,APBB1,APBB2,APC,SEMA4G,ARHGDIG,PDE8B,FUBP1,BAIAP3,CA12,SLIT2,ZFYVE9,ABCG1,CSNK1E,CHD5,ARHGEF4,DCAF4,KIAA0513,ELAVL3,C3orf18,EPB41L1,ARMCX1,FGF12,FGFR3,BAIAP2,FHL1,GABRG2,AHDC1,GLS,GRIK5,PADI2,KCND1,KCND3,MAP4,MGAT3,MYO6,MYO7A,NF1,NRCAM,RAB3A,MYH14,FAM214B,SHANK2,TRIM2,PCDHGA10,PSD3,FAM155A,LMF1,KLC2,SSPN" Drug 3304_UP Calciferol [50-14-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "KIDINS220,CDC42BPA,APC,MARK4,NRP2,CALB1,SLC16A4,CBFA2T2,NEURL1,FOXN3,SULT4A1,NCOR2,AATK,CSF1,CNTNAP2,RIMS3,LRRC23,SCARA3,GAD1,GRIK5,GRM1,GRM8,MAOB,MDM4,ADAM22,BCO1,MX1,PDE1C,PLCD1,PLTP,PACSIN1,GRAMD1C,RAB3IL1,ATG16L1,C1orf54,MYH14,CARF,SH3BP2,AMBRA1,FBXO11,SLC11A1,PEG10,INKA2,POPDC3,SZT2,ARHGEF12,DAAM2,KCTD2,CDK20,RUNDC3B,KCNK12,NUP214" Drug 3691_UP 0175029-0000 [211245-78-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "SLC12A5,NME5,PLA2G6,SYT13,BMP7,CD86,CHI3L2,CHN2,CHRM4,RIMS3,MFAP3L,ATN1,EFNB3,EGFR,DLC1,FGFR3,HPCAL4,FOXF2,GAB1,MYOZ2,PRUNE2,GRIA4,ITGA7,KCNMA1,CD200,LYRM9,FXYD7,PALM,PDE2A,CAMKV,NECAB2,LRRN3,KHDRBS2,RNASE1,RYR1,SLC8A2,MYH15,SOX2,IZUMO4,LHPP,ATP10B,SYT5,TAC3,PCDHGA10,DOCK9,CRTC1,ZFPM2,TNS1,TRIO,ZIC3,ZNF154,KCNAB1" Drug 1640_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.20E-05 1.00E+00 9.88E-04 1.12E-02 52 198 "AK2,LTBP4,CDC14B,CDK10,BCL2L2,BMP7,MTMR2,CACNA1D,ABCG1,LRIG1,PDE4DIP,DCAF8,C2CD2L,PARD6A,DNM1,F8,FGFR3,GPR153,GPR37,IL6ST,INPP5B,ITPKB,KHK,MAP4,SCAMP5,GIT1,SLC11A2,SETD4,MBOAT7,RIPOR1,NKAIN1,CEP97,SBF1,SGK1,FUZ,ABLIM3,BTBD7,EMC1,SPTAN1,TROVE2,CAMTA2,NCDN,MAPK8IP3,CEP68,VPS13A,EXOC7,KIAA0930,SIK3,KAT6B,TPM1,ZBTB38,WNK1" Drug CID000104999 DMCM Stitch 9.25E-05 1.00E+00 9.93E-04 1.13E-02 16 38 "CBR1,CCKBR,DBI,STX2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GRM2,PTCH1,SLC6A1" Drug 4651_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.72E-05 1.00E+00 1.04E-03 1.19E-02 48 179 "ADCY6,APAF1,PDXK,CANX,LRRFIP1,DCAF4,HDAC4,KBTBD11,ETV1,RACK1,FECH,FGFR1,CAMSAP1,ANKFY1,CAMKK2,CGREF1,ERAP1,DISC1,C1QL1,GNAS,GPD2,EML4,ARHGAP19,SHISAL1,DIPK1A,LAMP2,NACA,OPA1,PLCD1,MBOAT7,PLEKHB2,ATG16L1,SLC14A1,EMC1,CDK19,SYT1,TACC1,KIAA0930,ARHGEF12,DICER1,GPR161,ZMAT3,ZNF106,NACC2,CBX5,SLC38A1,FZD3,PHTF2" Drug CID000002554 carbamazepine Stitch 9.72E-05 1.00E+00 1.04E-03 1.19E-02 48 179 "ABAT,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,NT5C3B,APOC1,APOC2,CACNA2D1,ASIC3,CHRNA4,ABCG2,EPB41,CYP46A1,LOXL3,GRIK1,GRIN2C,GRIN2D,KCNA1,MAOB,MEST,NOVA2,PC,PDCD2,ABCB1,FSD1,PTCH1,SCN2A,SCN2B,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,BEX1,SST,TCF4,CUX2,TRH,TRPM2,SLC13A3,DPYSL5,NETO1" Drug 2711_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.97E-05 1.00E+00 1.07E-03 1.22E-02 49 184 "NDRG2,KIDINS220,C1QTNF1,BIN1,ANK3,DNAH17,CD86,CD38,CDO1,CHN2,SULT4A1,COL9A3,CREM,ABCG1,SIPA1L1,VCAN,PPP1R16B,PHF14,DOCK4,SNPH,DBT,FAM13A,PLXNC1,ZIC4,LILRA2,CACFD1,KIF5C,KIFC3,MEF2C,AFDN,OLR1,PLCD1,CEP41,PRKAR1B,PTK2,ACSS3,PBRM1,RPS20,SLC14A1,TMCC1,TAC3,CAMSAP2,GPR161,TLR4,TMOD1,UBE3A,BEST1,ZBTB38,NUP214" Drug CID005310936 Cgp 62349 Stitch 1.01E-04 1.00E+00 1.08E-03 1.23E-02 8 12 "CALB1,CALB2,CCK,GJB1,MAG,NPY,PMP22,SST" Drug CID000015450 M-HN Stitch 1.01E-04 1.00E+00 1.09E-03 1.24E-02 14 31 "ALDH7A1,PROM1,DTNA,PTPN5,HP,HPR,HTR2A,KIT,PDE3A,PDE3B,PIK3C2A,QDPR,RYR1,RYR3" Drug ctd:C514793 "gp120 protein, Human immunodeficiency virus 1" CTD 1.01E-04 1.00E+00 1.09E-03 1.24E-02 14 31 "ARRB2,SLC4A8,SV2B,ARNT2,ST8SIA3,LUZP2,KIF5A,NPY,NTRK2,ROBO2,FAM81A,NECAB1,SLC35G2,VGF" Drug 7438_UP Isotretinoin [4759-48-2]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "SERPINA3,ABHD6,AK2,ALCAM,BIN1,APBB2,APC,CFLAR,MTMR2,CA12,CREM,ENTPD4,CSF1R,HP1BP3,ATN1,SORBS3,ACSL4,B4GALNT1,SEPT9,RND1,GLYR1,GNG3,RASSF8,LMO2,MBP,SETD4,OPCML,PFKFB3,KLK6,CNNM2,RIPOR1,RAB3IL1,ATG16L1,RAP1GAP,RNASEL,PAQR6,NCBP3,SYBU,SLC22A4,SMARCD3,SNAP25,VAMP1,PLCB1,SEMA4A,TRIM2,CDK20,VLDLR,NAV2,MPPE1,MVB12B" Drug 2695_UP genistein; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "NR0B1,AZGP1,CACNA1G,SLC16A4,CD86,CDH10,CDO1,COL9A3,NRG2,CREM,ARHGEF10,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,DGKG,ST8SIA3,EDN3,SGK2,MBNL2,EGR3,FER,GCNT2,LYVE1,GLI2,PRUNE2,GRM1,RASSF8,KLF12,HPCA,IGSF1,KCND3,MOBP,ADAM22,RAB3A,CCDC40,RASGRF1,KLHL11,SUGCT,S100B,IL17RB,SLN,ZNF415,ARC,TRPC1,TRPS1,KCNK12,MAP3K12,EVI5,JPH3" Drug 6966_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "ADRA1D,OSBPL1A,BIN1,CDC42BPA,BCAS1,ATP2A2,CRY2,PUM1,EDRF1,ZNF337,BRINP1,MFAP3L,SGSM2,MED12,RASGRP2,F3,FECH,FHL1,HPCAL4,GPR153,GCK,TDRKH,GRIA1,SPACA9,CACFD1,NR3C1,ICA1,KCNC1,MAP4,MAPT,MGAT3,NAP1L2,PDE1C,RETREG1,MBOAT7,KLK6,RAB3IL1,MORC4,SBF1,HSPA4L,SH3BGR,PEX26,PKNOX2,SLC6A8,CCDC88A,ZKSCAN3,PCDHA6,TK2,ZMYND8,FXR1" Drug 5208_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "ADCY6,EPB41L5,PDXK,ATM,MPDZ,BMP7,SCARB1,FOXN3,QKI,ABCG1,MFAP3L,C2CD2L,DTNA,EGR3,ENO2,FGFR3,DPYSL4,FAM49B,ZNF44,FERMT2,NR3C1,KCNH2,PCDH9,PIK3R1,SLC25A23,STRN3,LRP12,MBOAT7,PRODH,PTPRE,RXRA,ANKRD6,SHANK2,SMARCC2,ZHX3,ZSWIM8,PHLDB1,TACC1,TCF7,TNS2,CABIN1,TRIO,SSBP2,ZKSCAN5,CADM1,UBTF,LMF1,KLC2,UPF3A,EMSY" Drug 1288_DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "ACTN1,PPFIA1,APP,ARNTL,CFLAR,CCNT1,CD86,CNOT8,CLCN3,AKAP7,C2CD2,NCOR1,PPP1R16B,CTIF,PLEKHO1,WAC,ZNF589,PCYOX1,HBS1L,ARFIP1,CRCP,SMAD1,MEF2C,ODF2,OGG1,PDPK1,LRP12,PMS2,PTPA,PKN2,PSMD13,PLEKHB2,ATG16L1,RGS10,KDM4B,DOP1A,ZCCHC24,CDK19,ZBTB43,PRRC2C,EHBP1,TCF4,DICER1,TMPO,PARD3,CADM1,PLPPR2,NSD2,WNK1,SNX27" Drug 6694_UP Loxapine succinate [27833-64-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.02E-04 1.00E+00 1.09E-03 1.24E-02 50 189 "ADCY6,APAF1,APC,GAS7,SLC4A4,SCAPER,CAPN3,CBS,TAOK2,CLCN4,QKI,PCYT1B,MICAL2,PDE4DIP,CTNND2,ATN1,ECM2,HIPK3,SEMA3D,EFNA3,MBNL2,FER,CAMKK2,GAB1,GAD2,DISC1,RND1,SOX21,IGSF1,KITLG,MYH7,NELL2,NF1,NHLH1,PDE4A,PDGFRA,ZSCAN32,EMID1,FOXRED2,SCN2B,OGDHL,EMC1,ZC3H13,RPGRIP1L,AP4E1,ZMYND8,ZNF24,REEP1,PRDM10,SCG2" Drug CID000000761 5'-GMP Na2 Stitch 1.03E-04 1.00E+00 1.11E-03 1.26E-02 79 335 "BRAP,APBB2,ALS2,CASK,ALDH7A1,NIPA1,CACNB2,CALM1,CCNH,ENTPD6,MAGI1,DLGAP1,CLTA,TJP2,MAP4K4,ENTPD4,GDA,DLG2,DLG3,DLG4,DNM1,DNM2,ABCC5,DNM1L,EDN1,ATL1,EFNB3,CELSR3,ELN,ERCC2,ETV1,GMPR2,NELFCD,SORBS1,NRG3,MTHFD2,SEPT9,GRIN2C,GRIN2D,GUCY1A2,GUCY1A1,GUCY1B1,TNFAIP8L3,IRF8,ITIH2,KCNA2,KCNA4,SMAD1,NOS1,NPPA,NPR2,TBC1D25,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,POLR2F,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RNASE1,S100B,MAPK12,CNKSR2,NMNAT2,SUPT5H,VPS13A,SYNE1,TJP1,PRTFDC1,SSPN" Drug 3676_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "DPF1,APAF1,BCAS1,SPTBN4,PDE8B,N4BP2L1,ADAM23,BMP7,CACNA1I,CFAP410,CACNA1E,CACNG1,CHGB,CHN2,SUSD5,ATRNL1,CNTNAP2,DGKB,SHANK1,SNX29,RGS17,ETV1,ABCA8,FABP7,FGFR1,C1orf61,ERGIC3,RUNDC3A,RND1,GRM7,ATXN2L,HLF,KIFC3,MBP,AFDN,NF1,PLP1,MINDY2,KHDRBS2,MYH14,RAVER2,CARF,SLC15A2,PDZRN3,SOX10,NFASC,SLC44A1,PDIA2,ZNF154,KCNAB1,EPM2A" Drug 2087_DN Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ADD1,APC,ATM,CFLAR,CACNG1,CCNT1,CNOT8,ZFYVE9,NIPBL,HOMER3,FAM169A,ARHGAP32,PARD6A,DLG3,DYNC1I1,EGFR,ELAVL2,COQ7,STX2,ZNF589,FGFR1,MAP4K5,IFI16,IL11RA,MPP2,OGG1,LRP12,POLG,SYTL2,PTHLH,TMEM260,RIPOR1,ASAP3,AMBRA1,BTBD7,ERC1,ZBTB43,EXOC7,FBXW11,TBL1X,TRIM2,TNS2,TRIO,HIRA,NPDC1,UPF3A,PRDM2,NT5M,SEMA3B,EPM2A,SSPN" Drug 3273_DN Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "AP2A2,ALK,DOC2A,CDC42BPA,APBA2,GAS7,ASPH,ATM,CFLAR,CAMK2G,CACNA2D2,TAOK2,FADS2,NECTIN3,CSF1R,SOCS5,RABGAP1L,RCAN1,CNNM1,HSD17B14,STX2,ERCC2,EXTL2,FOXG1,ANKFY1,FAM49B,OGA,INPP5K,USP19,GNG4,SPACA9,NR3C1,GSN,TJAP1,NEK1,NPTX1,SETD4,PRKAB2,PRKAR1B,CNNM2,ATG16L1,RGS3,RGS12,GSTCD,RPS6KA2,RASA3,EPN2,DICER1,TRIO,TRPC1,REEP1" Drug 3527_DN Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "KIDINS220,PLA2G6,CDC42BPA,PPFIA3,CDC14B,ARRB1,MARK4,CAMK2G,SOCS6,B4GALT6,TAOK2,HOMER3,NCOR1,CSF1,GREB1,CTIF,RCAN1,TOM1,SIDT2,MBNL2,EIF4G2,EN2,LRRC23,FHL1,FLNC,FAM49B,GPR153,GAB1,GALC,JAK2,KCNH2,MID1,PC,SMOX,PRKAR1B,PRODH,TMEM104,DCUN1D2,UNC5B,PHLDB1,ATP11A,EXOC7,TCF7L2,RPGRIP1L,SLC44A1,PLPPR2,SPHK2,SEMA3B,NAV2,KAT6A,SSPN" Drug 4678_UP Haloperidol [52-86-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ASPHD1,ADCY6,ADGRF5,LTBP4,CDK10,KIF1A,ADGRB1,CACNA1A,CDH8,GPR37L1,TPP1,DNAJB5,AKAP5,C2CD2L,DMPK,ST8SIA3,ETV1,FGFR1,SIGLEC8,MYOZ2,GLI2,GPM6A,GRIN1,CACFD1,HPSE2,SCIN,ADAM11,MYH3,NF1,P2RX7,PDE4D,PENK,MINDY2,PPP5C,PROX1,RGS12,EMID1,SLA,ZNF334,ZHX3,IZUMO4,SPTB,IQSEC2,SYN2,TAL1,DOCK9,TUBB1,NSD2,WNK1,PRDM2,SLC17A7" Drug 6660_DN Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ARID1A,KIDINS220,PLA2G6,AMT,APAF1,PDE8B,MARK4,SCAPER,CFAP410,CACNA1A,ARHGEF1,SEPT7,CDC42,ARHGAP33,VCAN,SGSM2,CDON,SGK2,SIDT2,CELSR3,LRRC23,MTSS1L,KIAA1109,FYN,ZNF44,CRCP,LPAR4,GRM8,ARHGAP19,HLF,SCIN,GIT1,PTPA,PRKAR1B,PTN,PTPRH,TTLL7,MYH14,ATXN7,DZIP1,EMC1,TROVE2,THSD1,NCDN,SMG6,SLC44A1,OSBP2,VGF,WIPF1,NUP214,TIGD6" Drug 4599_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ALDH4A1,KIF1A,CACNA1A,FOXN3,DNAJB5,HOMER3,TOM1,DUSP9,FEM1B,CELSR3,IRAK4,ELAVL3,LRRC23,ETV1,F3,FGFR1,CINP,PRELID3A,INPP5K,SRCAP,LPAR4,ITPKA,KCNJ4,KCNJ5,MAP2,MBD1,NOS1,NTRK2,PROX1,CNNM2,SAMD9,PTPRN2,FAM184A,RNASEL,DCUN1D2,ROM1,TCP11L1,SLC1A7,VAMP1,SMG6,TK2,VGF,VIPR2,WIPF1,XRCC4,ZIC3,PARP6,SCG2,KCNAB1,TIGD6,SENP7" Drug 4132_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "AP2A2,NME5,MRTFA,CDC14B,BRINP2,SLC2A11,CFAP410,MAGI1,ADGRG1,PLEKHB1,B4GALT6,STOML1,FADS2,HOMER3,SH2B1,DBN1,C2CD2L,SGK2,EFNB3,ING4,ENO2,EPB41L1,FGF13,CAMSAP1,GPR153,GAD1,GPR19,GRM8,ELOVL5,INPP5B,KCND3,AFF1,ADAM22,NOS1,SLC11A2,KCNK10,SERPINI1,MBOAT7,ELOVL2,PTPRO,TCP11L1,TSNAXIP1,IQSEC2,THSD1,ZNF34,SLC44A1,TPD52,KCNK12,MAP3K12,EMSY,PCBP4" Drug 1670_DN Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "EP400,DGKD,ATM,RIPK1,MPDZ,MTMR2,ZMYM4,SRSF11,NIPBL,SMARCAL1,DCAF8,KIAA0586,C2CD2L,MED24,DLG3,DMPK,SORBS3,VPS26C,ARMCX1,FAM49B,INPP5K,FERMT2,KIF3A,RNFT2,MEIS1,RETREG1,PKN2,SIDT1,PAQR6,ITSN1,NUBPL,EPN2,SMTN,SLC20A2,CDK5RAP2,KDM4B,SPTAN1,CDK19,SS18,KANK1,TACC1,EXOC7,TRIM2,DOCK9,PSD3,TP53BP1,METTL3,ZMYND8,WNK1,SEMA3B,MPPE1" Drug 3556_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "NDRG2,ADORA2A,SPARCL1,APC,AQP4,BSN,CFAP410,CA4,MTMR7,ARHGAP33,PLEKHB1,LY86,ATRNL1,ARHGAP24,TOX,RIMS3,ARMCX2,KLHL3,LRRC23,LRRC17,IGSF6,KHDRBS3,GAD1,RND1,SPACA9,KHK,LMO1,MAOB,MSR1,MYO7A,NF1,PALM,GPR85,PPP2R2B,MAPK10,PTPRH,C1orf54,PNMA8A,FNDC3A,ST6GAL1,RPH3A,PEG10,ARHGAP26,TSPYL2,SYT5,ROBO3,TBCEL,TRIO,DNAJC12,NT5M,AP3B2" Drug 6201_DN Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ADD2,APBB2,SEMA4G,ASPH,ADAM23,SCAPER,CAMK2G,CAPN3,AP4M1,TAOK2,CPS1,CTH,TBC1D5,SPATA2,SGSM2,EIF1,PTK2B,FECH,FOXG1,ANKFY1,FAM49B,CAMKK2,FYN,GLYR1,CACFD1,VWA5A,CNOT4,OGG1,PDE4D,PPP5C,GON4L,NCBP3,FOXRED2,ST6GAL1,SLC1A3,RAB3GAP1,KIF1B,TSPYL2,FAM168A,ATP11A,KAZN,CAMSAP2,ZKSCAN5,HIRA,PLPPR2,VLDLR,XRCC4,ATP6V0E2,ZNF225,KCNAB1,ACTR3B" Drug 4401_UP Apigenin [520-36-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ASIC1,ADORA1,ANK1,ASCL1,AZGP1,CACNG1,KALRN,RUNX1T1,CBFA2T2,DLGAP1,CBARP,SULT4A1,IFFO1,HDAC9,DAPK1,SPOCK3,SRGAP3,TRAPPC9,EDN1,EGR3,LRRC17,CDKL3,F5,DLC1,OLFM1,DLL3,FYB1,SESN1,GLS,GRM1,VWA5A,ZNF862,NEFM,NPY,NTRK2,CDK14,TNPO2,PYGM,ZMAT4,DCUN1D2,EMID1,RPS20,PAQR6,SEMA6D,SLC2A5,KANSL3,TIMP4,HEY2,WIPF1,XRCC4,KCNAB1" Drug 7523_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "BIN1,CDC42BPA,PPFIA3,CDK13,CAPRIN2,EIF4G3,BTRC,CA4,CAMK2G,ARHGAP33,CSF1R,RIMS2,GIT2,DBN1,DTNB,TOM1,PHF20L1,LRRC23,DLC1,ZNF589,FER,FGFR1,GNG3,GRB10,DHX35,IL6R,LIG4,SMAD1,MMP17,NF1,CDK18,RAD52,DCUN1D2,GSTCD,ROM1,TCP11L1,RPS6KA2,RYR1,FOXRED2,DOCK10,NXT2,INKA2,JMJD6,TCF7,PCDHA5,ZNF34,TMOD1,SPHK2,TFIP11,FIP1L1,RNF170" Drug 6893_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ASIC1,AP2A2,ANK3,APBB1,ARNTL,ADGRB2,NEURL1,WHRN,ABI3BP,CNTNAP2,TOX,FAM13A,LPAR6,SORBS3,ING4,ETV1,FHL1,CINP,DLL3,GPR17,GPER1,GRIK5,KLF12,ZNF862,PIK3CD,CCSER2,RETREG1,PLEC,EPN1,MED1,BCAS3,PTPRH,BEND5,TMEM156,IL17RB,ZNF821,SMARCD3,SNCA,CDK19,COLGALT2,VAMP1,ARHGEF9,SYT1,WSCD1,TNS2,TMPO,CABIN1,LMF1,ZNF32,ZNF74,NAV3" Drug 4758_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "NME5,AMT,CADM3,CFAP410,ARHGEF2,FOXN3,TAOK2,WHRN,RCHY1,CNTNAP2,RIMS2,CTIF,MFAP3L,PARD6A,RABGAP1L,ATN1,SIDT2,EGFR,ST3GAL6,FGFR1,AFF2,GAD1,GRM8,SLC2A6,HNMT,LMO2,MEF2C,MID1,AFF1,GIT1,ADAM22,MYT1,NF1,NFYA,NUMA1,OGDH,RETREG1,PRKAR1B,ZSCAN32,FAM120C,KCTD17,ZNF821,FNDC3A,SLC1A7,SMARCD3,EMC1,ZNF423,TMEM121,TRPC1,ZIC3,SPHK2" Drug 5609_UP Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "DPF1,PLA2G6,AMPD3,APBA2,ASCL1,SLC2A11,ADAM23,CAST,RUNX1T1,NEURL1,CNTFR,ARHGAP24,CTIF,DCT,SPOCK3,ATN1,ELAVL2,EPHB1,FYN,GABRG2,POLL,PRUNE2,STON1,GRM7,SYNPO,HNMT,KCND3,KIF5A,MAOB,TAGLN3,NTRK2,OPCML,PDE1C,PGAM2,PURG,PPP2R2B,PTPRE,TRIM68,ZFP2,KANSL3,ARHGEF40,SNCA,KIF13A,KDM4B,POPDC3,ZEB1,UCHL1,FLRT2,MICAL1,SPHK2,MARCH8" Drug 1924_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "RBM10,C1QTNF1,MAP4K3,APP,ARHGAP5,WASF1,ARHGEF2,QKI,SLC4A7,CDC42BPB,RNF14,APPL1,MATR3,ABI1,ETV1,ST3GAL6,FGFR1,UFM1,CAMKK2,NCKAP1,GLS,HTATSF1,OS9,MAP4K5,KIF5C,KTN1,MARK3,SCAMP5,NAP1L1,CDK14,CCSER2,GPSM2,STRN3,PTK2,C1orf109,RPRD1A,CCDC25,FNDC3A,FAM214B,SON,FNBP1,EMC1,PEG10,CLASP2,EPB41L3,LARP4,STAU1,DMXL2,DOCK9,ZNF195,PARP6" Drug 4171_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "NDRG3,NDRG2,AMPD3,BIN1,BCAS1,MARK4,ALDH7A1,SCAPER,C5,CFAP410,CACNB2,CHD1L,SH2B1,SNCAIP,RASSF2,SPOCK2,SMG7,EGFR,PLXNC1,ING4,ELN,ERCC2,CDKL3,PIPOX,FGFR1,AFF2,PRELID3A,GAD1,SEPT9,RND1,PRUNE2,ELOVL5,ITIH2,KIT,IPO5,SMAD1,ADAM22,MYT1,NEK1,NRGN,PRKAR1B,MAPK10,SAMD9,RAD52,CCDC25,SH3GL3,PEX26,RBM34,TRIM2,VIPR2,XRCC4" Drug 7529_DN Suramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "MRTFA,PKP4,APOC1,BID,RAB28,COL9A3,ENTPD4,NCOR1,NCOR2,ATN1,MBNL2,MRNIP,TESK2,SORBS1,CINP,USP19,HTATSF1,GNG4,IL12A,KHK,MMP17,TAGLN3,ODF2,PALM,PFKFB2,MAPK7,BCAS3,PTPRN2,TMEM231,GAL3ST4,RAVER2,GSTCD,SCG5,KIF16B,ST6GAL1,DZIP1,SLC4A3,COA1,MYH15,WDTC1,BEX1,SPTAN1,ARHGEF9,ATP11A,TRIM2,RPGRIP1L,CHST5,HIRA,PDIA2,WNT7A,KCNK12" Drug 4599_UP Tadjakonine [11087-94-8]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "APC,C5,CACNA2D1,KRIT1,CLCN4,CREM,DZIP3,PHF14,DBT,RABGAP1L,DSCAM,DTNA,ING4,EML1,RRAGB,CORO2B,KIAA1109,TRMO,GAB1,MSL3,GPD2,CNTRL,IGSF1,ITGA7,JAK2,LIG4,MBNL1,PALM,PDE4D,PFKFB2,RETREG1,SPATA6,MINDY2,ZSCAN32,PTPRB,CCDC40,FBXW7,MCMBP,FBXO11,OGDHL,SNAP25,TNIK,CDK19,TROVE2,MLC1,TCF4,TMPO,CHST5,VAV2,ZNF225,NUP214" Drug 5791_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-04 1.00E+00 1.11E-03 1.26E-02 51 194 "ACTN2,AP2A2,NME5,TRMT9B,RASL11B,BMP7,MYRF,HAP1,RUNX1T1,FOXN3,PICK1,WHRN,AKAP5,FEZ1,ATRNL1,RIMS2,RIMS3,SPOCK2,HS3ST2,COQ7,PDLIM5,GPD1,SOX21,ATXN2L,KLF12,KIT,MAPT,GPR85,PIK3CD,PLCD1,POU3F4,PPP2R2B,CNNM2,NKAIN1,ACSS3,RGS4,RGS12,RPS6KA2,KCNIP1,SEMA6D,SNCA,SOX10,ZBTB43,SSTR2,MCF2L,CRTC1,ZFPM2,CRB1,THBS4,BHLHB9,RUNDC3B" Drug CID003518809 Clorocruoro Hem Stitch 1.06E-04 1.00E+00 1.11E-03 1.26E-02 36 123 "ACHE,ATP2A2,ATP2B1,BCHE,CALM1,KYAT1,CCK,CCKBR,CHRM1,CHRNA4,CHRNB2,PLCXD3,DMPK,EDN1,PTK2B,PLCD4,MYLK2,NOS1,PLCB2,PLCD1,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RET,RTKN,RYR1,RYR3,MAPK12,ATXN1,PLCB1,TPD52,TRPC1,TRPC3" Drug 4705_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "APLP1,BCAS1,APP,MARK4,SCAPER,MTMR2,GYG2,PTBP2,MAP7,FAM189A2,NCOR2,DNAJC6,JAKMIP2,RABGAP1L,DLG3,EFNA3,HSD17B14,DENND4A,FYN,ERAP1,GFER,MSL3,GNG4,TDRKH,CNTRL,ITPKB,MBD1,MIA2,MPP2,ADAM22,NEUROD1,SERPINE2,RETREG1,GTDC1,RGS10,FBXW7,SLC15A2,SOX2,ZCCHC24,MAPK8IP3,VPS13A,FBXW11,RPGRIP1L,THRA,TK2,XRCC4,MAP3K12,EVI5,SEMA3B,MVB12B,KAT6A,TIGD6" Drug 4438_DN 2-propylpentanoic acid; Down 200; 200uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "APBB1,PPP4R4,ATP1A3,SLC4A4,ADAM23,SCAPER,MTMR3,CACNB2,NEURL1,ARHGAP33,NRXN3,AKAP7,IQCK,MICAL2,ARHGEF4,DAPK3,EIF4G2,SORBS3,EZH1,CGREF1,GABRA2,HBS1L,NEU3,SRCAP,POLL,GRIK5,GRM1,ATXN2L,SHISAL1,SCIN,IL11RA,KIT,NF1,SLC25A23,POU3F2,WDR25,PTPRE,ZSCAN2,KIRREL1,ATXN7,MRAS,FBXO11,SLA,SLC1A7,PPP4R3A,TMCC1,UNC5B,DDN,MAPK8IP3,VIPR2,SCG2,DPF3" Drug 3361_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADORA2A,ADRA1D,MARK4,BMP7,ADGRG1,FOXN3,CLU,VAX2,MICAL2,PPP6R2,RABGAP1L,DPH1,FEM1B,IRAK4,LRRC23,STX2,CINP,INPP5K,GCNT2,SRCAP,GNG3,GPR19,NR3C1,BTN2A1,INPP5B,LSS,MPP2,NTRK2,NUMA1,PLCD1,SLC25A23,PPP5C,PRKAR1B,PTN,ZSCAN32,RBM34,WDTC1,SPTAN1,SPART,PLCB1,ANKRD12,SIK3,RBFOX2,TPM1,ZKSCAN5,VGF,VLDLR,ZNF45,SYNC,WNK1,EPM2A,MARCH8" Drug 5869_DN Pyrilamine maleate [59-33-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABHD6,AK2,AMT,APLP1,APOC1,MARK4,OSGIN2,CLCN3,FADS2,NRG2,CSF1,ZNF337,KLHL3,DLG3,LPAR6,EIF5,ING4,TNK2,MRNIP,EPB41L1,ETV1,ANKMY1,ZNF589,FGF13,SEMA4D,PRRC2B,GPER1,BTN2A1,RNFT2,SYNPO,ITPKB,IPO5,MBD1,MIA2,TAGLN3,CCSER2,LRP12,SUPT20H,ZNF430,TMCC1,SPATA7,TROVE2,MAPK8IP3,GSE1,IQCE,SLC35G2,CBX5,HIRA,UBTF,EMSY,PLSCR4,AAAS" Drug 2347_UP Tropicamide [1508-75-4]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADRA1D,PLA2G6,BIN1,DNAH17,SYNJ2,PPP1R16B,DAPK3,ARNT2,TRAPPC9,CELSR3,MRNIP,COQ7,RRAGB,GAA,SEPT9,INPP5K,WASF3,GNG3,LPAR4,ADAMTS13,GUCY1A1,KLF12,HTR2A,SCIN,KCNJ5,MID1,AFDN,SLC11A2,NTRK2,OPRL1,PPP1R1A,LRRN3,ZCWPW1,KHDRBS2,SBF1,SCN2A,CXXC4,SNCA,NFASC,ATP10B,SYP,TACR1,SZT2,GPR161,TGFBR3,TIAM1,TMOD1,AMACR,ZBTB38,MAP3K12,KCNAB1,PCBP4" Drug 495_DN WY-14643; Down 200; 100uM; SKMEL5; HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC1,AK2,ATP6V0A1,BARD1,MAP4K4,RIMS2,DAPK1,CTIF,DTNA,SUGP2,PLXNC1,ZMYND10,PDLIM5,GAD2,PPARGC1A,PRRC2B,GRIK5,IRF8,MBD1,NASP,NUMA1,OCRL,PC,CCSER2,STRN3,PPARA,CEP41,ZSCAN32,RAB3A,RASGRF1,ZFHX4,DCUN1D2,ATXN1,SELL,STUM,SLC1A2,SMARCC2,RCOR3,SRPK2,DOCK9,CRB1,KCTD2,TP53BP1,SEZ6L,METTL3,TRPS1,TUB,BEST1,ZBTB16,GDPD5,LMAN2L,MVB12B" Drug 5458_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AP2A2,APBB2,PPFIA3,CDC14B,ARHGDIG,ARRB1,CAPRIN2,BRINP2,ATM,SYNJ2,BAIAP3,CBFA2T2,CLGN,QKI,ARHGEF6,ABI3BP,CRY2,SIPA1L1,PDE4DIP,PPP6R2,KIAA0586,DSCAM,PLEKHO1,VPS13B,ZNF589,FHL1,B4GALNT1,AHDC1,GPM6B,GPER1,INPP5B,JAK2,KIF2A,NDUFA5,NTRK2,SERPINE2,SMIM7,LRP12,GON4L,PTHLH,NKAIN1,RAD52,LIMCH1,MAPKBP1,KDM4C,ATP11A,SEMA4A,EXOC7,IQCE,EVI5,GDPD5,SENP7" Drug 3224_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "RALGAPA1,ASIC2,AK2,FAM135A,GAS7,BACH1,CFLAR,MTMR3,CACNB2,RUNX1T1,CHI3L2,CNTNAP2,RIMS2,SNPH,EDN3,EFNB3,PLXNC1,PIPOX,ZNF589,FGFR3,SORBS1,ZNF44,HBS1L,ERAP1,RUNDC3A,RAB30,LPAR4,GRIK5,C2orf72,KCNH2,MAP2,TAGLN3,TREM2,PLP1,MBOAT7,PTHLH,WLS,PKNOX2,SNCA,FAIM2,DOK5,ARHGAP26,SPTB,ATP10B,SYT5,DOCK9,HIF3A,TPM2,TRPC1,TRPC3,XRCC4,SSPN" Drug 4087_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "PLA2G6,AMH,KCNAB2,CDK10,PPP4R4,NRP2,SYNJ1,CBFA2T2,FOXN3,RAB26,AKAP7,AKAP5,TENM4,ARHGAP24,DAPK3,MFAP3L,DLG3,ABCC9,IRAK4,DMTN,MTSS1L,ZNF549,ETV1,FGF1,IQCG,FLT1,FYB1,GAB1,ATXN2L,ICA1,IL6ST,MEF2C,AFF1,PDE1C,GPR85,PIK3R1,ZSCAN32,PTPRH,ZSCAN2,BEND5,ZMAT4,RGS12,FBXW7,RPS20,CEP68,PCDHA5,GPR161,TK2,CABIN1,LILRA4,NT5M,GAN" Drug 1935_DN Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "NDRG3,PLA2G6,APBB2,PDXK,SYNJ2,MAP7,CDC27,CDH2,PPP6R2,SPOCK2,SIRPA,DNAJC6,KCTD3,SORBS3,FGFR1,CAP2,CAMKK2,ATP2C1,STAU2,MPP6,STAG2,TRAF3IP2,CRCP,GLS,OS9,GRIK5,GUCY1B1,HAS2,MAP4,MEF2C,MX1,NFYA,PAK3,CDK14,PTPA,CNNM2,RAP1GDS1,RBBP6,MYH14,ABLIM3,SLC11A1,ELMO2,SMARCC2,NMNAT2,ZBTB43,CEP68,DMXL2,TRIM2,TRPM2,DNAJC12,KLC2,ZNF32" Drug 6735_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABAT,AP2A2,AQP4,ADGRB2,BMPR1B,BAIAP3,CFAP410,CAPN3,DLGAP1,VAX2,ABCG2,COL9A3,IPCEF1,ARHGEF4,SPOCK2,CTIF,ABCC9,EDN3,ERBB4,APC2,AGAP2,CSPG5,SIGLEC8,GPD1,PRUNE2,TDRKH,PTGDR2,ICA1,KCNH1,ADAM11,ADAM22,NTRK3,P2RX7,GPR85,PMP2,PPP5C,WDR25,ASIC4,ZFP30,SLC11A1,SPART,SYT5,TACR1,PCDHGB6,SPX,TLR4,SLC30A4,EMSY,DNALI1,MVB12B,NLRP3,JPH3" Drug 7331_DN Naftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABR,AP2A2,APC,ATP6V0A1,MTMR2,MAP7,LRRFIP1,SMARCAL1,EDRF1,ZFYVE16,GIT2,DBN1,LYPD1,DNM1,CELSR3,ENO2,FAM49B,GLUL,KCNH2,LSS,MAP4,MATK,NF1,NFYA,NPR2,RETREG1,MAPK8,CNNM2,TMEM231,RAB3A,RNASEL,GSTCD,NEK11,SUPT20H,PPP4R3A,ZKSCAN3,SMARCC2,PDZRN3,WDTC1,POGZ,THSD1,ELOVL4,SEMA4A,IQCE,TMEM121,ZBTB14,REEP1,FTSJ1,UPF3A,MAP3K12,MPPE1,EPM2A" Drug 4065_DN Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASPHD1,AMH,AQP4,ASTN1,ATP1A3,NOL4,CBFA2T2,ARHGAP22,LHX2,DNAJB5,RAB26,TCEAL2,CREM,TENM4,ARHGEF10,ARHGEF4,RIMS2,CTIF,BRINP1,MFAP3L,ABCC9,ST8SIA3,EIF4G2,MTSS1L,ST3GAL6,EFCAB2,ZNF44,SRCAP,GRM1,MAPT,MGAT3,MOBP,ZNF862,OPCML,PRKAR1B,MAPK7,FAM120C,RAB3IL1,RGS7,RGS10,SLC1A7,SNCA,IQSEC2,TSPYL2,ACSBG1,ADGRL3,PCDHA5,TK2,R3HDM1,VIPR2,ZIC3,STMN4" Drug 4774_UP Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "SYN3,ACTN2,KIDINS220,AK2,SEMA7A,APBA2,ASCL1,MARK4,MPDZ,RGS9,CFLAR,CACNA1I,BTRC,SEPT7,CLGN,NCOR2,TENM4,VCAN,PUM1,SPOCK2,EFNA3,EIF4G2,ELAVL2,HSD17B14,ERCC2,ACSL4,ZNF44,ALDH1L1,PCLO,GRM8,ICA1,C2orf72,KCNN2,KIT,VWA5A,MID1,MMP16,NDUFA5,PDE4A,LRRN3,FRMPD1,SLA,ZC3H13,WSCD1,TCF7L2,RPGRIP1L,PSD3,CRTC1,CABIN1,UCHL1,CLDND1,ST7" Drug 2693_DN rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "TRMT9B,APC,LGR5,CACNA1G,LDLRAD4,PLAA,NCOR2,CX3CR1,ARHGAP32,BRINP1,RUSC2,CDON,DYRK1A,MBNL2,ELN,MTSS1L,ST3GAL6,KIAA1109,ZNF44,INPP5K,GATM,RUNDC3A,ATXN2L,ICA1,MAP4,MGAT3,AFDN,MYCN,MYO6,OLR1,SYTL2,WDR25,ZSCAN32,KHDRBS2,CCDC92,ANKRD6,SLC6A8,WDTC1,IZUMO4,ARHGAP26,IQSEC2,MAPK8IP3,ARHGEF9,ROBO3,TCF7L2,TNS2,TPM3,LMF1,CLIP2,XRCC4,ZNF711,PCBP4" Drug 4606_UP Metyrapone [54-36-4]; Up 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABAT,SYN3,SEMA6A,CDC42BPA,ANK1,APOC1,B3GALT2,KSR1,BMPR1B,HAP1,CAMK2B,NEURL1,DNAJB5,NRG2,ARHGEF10,MICAL2,PDE4DIP,SPOCK3,SGK2,ZNF549,EZH1,AGAP2,DOT1L,FYB1,GAB1,ARPP21,SYT17,NEU3,HPGDS,HNMT,MSR1,NF1,PTPRN2,C1orf54,ZCWPW1,SELL,SH3BP2,CNKSR2,ANKRD6,KANSL3,DDN,SPART,SAMSN1,SYP,ADGRL3,OBSL1,SEZ6L,TRPC1,VIPR2,PRDM2,SENP7,JPH3" Drug 315_UP "aspirin, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "KDM5D,NR0B1,ALK,BIN1,ANK1,CDC14B,KIAA1614,DNAH17,CACNA1A,CDH10,ARHGAP33,AK5,ING4,STX2,ERCC2,CDKL3,ZNF589,NSG2,GAB1,TRAF3IP2,CYP46A1,MCHR1,GRM8,SOX21,NCKAP1L,KCNJ5,MID1,NPTX1,OPCML,SNTG1,LRRN3,WDR25,RFX2,ASIC4,ITSN1,FRMPD1,FNDC3A,ST6GAL1,SLC8A1,ARHGEF40,NMNAT2,UNC5B,SYN1,OBSL1,PCDHA5,CDH22,TNS1,TRPC3,VIPR2,SLC13A3,HRASLS,AP3B2" Drug 5449_UP Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ACTN2,PPP4R4,RGS20,PTCH2,KSR1,CACNA1I,CFAP410,EPS15L1,ZFYVE9,CLCN4,CNN3,CNTNAP2,RIMS2,NOS1AP,TOX,CTIF,ATN1,SIDT2,FAM13A,FAM198B,ZNF589,FGF1,FOXG1,PCDH17,GUCY1A2,IRF8,ADAM22,TAGLN3,NCAM1,RELN,PTAFR,RAB3A,STUM,FNDC3A,ARHGEF40,CXXC4,SOX2,ZCCHC24,KIF21B,ZHX3,JMJD6,POPDC3,PCDHA5,GPR161,HEY2,TNS1,UCHL1,WNK1,MVB12B,PLSCR4,TIGD6,DPF3" Drug 3780_DN Proglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AMPD3,APBB1,ZSCAN18,BMP7,BTRC,CFAP410,CACNA2D2,ABCG2,LY86,AKAP5,HAPLN1,VCAN,CNTNAP2,CTNND2,DCAF4,EDRF1,DTNA,ANKFY1,PDLIM5,OGA,GAD2,ATP8A2,KLF12,ICA1,NELL2,NF1,PALM,PIK3R1,KCTD15,RAB3IL1,RGS4,IL17RB,DZIP1,SLC6A9,OGDHL,RBM34,UNC5B,THSD1,MAPK8IP3,SYN2,FBXW11,ZEB1,CRTC1,TK2,CABIN1,TNS1,ZKSCAN5,VAV2,LMF1,WNK1,DPF3,SENP7" Drug 2316_UP Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "DPF1,SYN3,ARHGDIG,ASCL1,CFLAR,GYG2,BSN,CACNA1D,NGB,HIP1R,ARHGAP33,CLGN,CHN2,CLCN4,FADS2,NRG2,CYBB,RASSF2,MAML1,DLG2,DUSP9,VPS13B,RCAN2,RRAGB,ZNF589,FGF12,FGFR1,RND1,GLS,POLL,LSS,NDUFA5,NF1,NUMA1,PDE1C,SERPINE2,LRP12,NECAB2,C1orf54,EMID1,PKNOX2,PEG10,SPTB,THSD1,ZC4H2,MAPK8IP3,ACSBG1,ARC,PSD3,PIK3R5,MPPE1,PHTF2" Drug 6123_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "RALGAPA1,ABAT,ASIC1,NDRG2,MTUS1,ALAD,CNTNAP1,APAF1,ATP6V0A1,SGCE,CAPN3,CHM,CRMP1,CSF1,PHF14,DBT,RUSC2,SMG7,CDON,TOM1,STX2,PIPOX,GAA,GABRA4,ALDH1L1,USP19,GLYR1,GNG3,SPACA9,ITIH2,KHK,MAP4,SCAMP5,MID1,MOBP,CNOT4,PDE4B,SERPINE2,RETREG1,PLCD1,PPARA,PPP5C,PTCH1,PAQR6,AMBRA1,JMJD6,SYN2,TGFBR3,RBFOX2,TPM2,ZFP37,KCNAB1" Drug 6828_UP Piretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADCY2,BEGAIN,GAS7,SEMA4G,ATP2A2,ADAM23,HIP1R,NEURL1,CDO1,SOCS6,SLIT2,PDE4DIP,SPOCK2,DMPK,RBM12,PLXNC1,RASGRP2,FGFR3,FHL1,FOXG1,DPYSL4,SORBS1,GLYR1,HTATSF1,RAPGEF1,GRIK5,NR3C1,KLF12,IL6R,ITGAM,KCNB1,MYT1,OPCML,KCNK10,PDE4B,TNPO2,PTAFR,RIPOR1,ZDHHC14,PNMA8A,TCP11L1,SELL,ASAP3,FAM214B,SHANK2,KDM4B,WDTC1,KIF21B,RGL1,ATP11A,WSCD1,MKRN3" Drug 2476_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABAT,ALK,PTCH2,ATP2B2,KSR1,CAMK2B,ARHGAP33,CDO1,NRXN1,NRG2,CREM,RIPOR2,ZIC4,FLT1,SOX21,HRH3,SCIN,KCNA4,KIT,MAP4,MAPT,AFDN,CD200,MYCN,NINJ2,NOVA2,CCSER2,PLEC,POU3F4,PPARA,LRRN3,MAPK10,KLK6,KCNIP1,SLC11A1,SHANK2,SLCO1A2,SLN,SNCA,MYT1L,HECW1,SPTAN1,ATP10B,SYNE2,PLCB1,AHCYL2,TRPC1,LMF1,VSNL1,SLC13A3,SLC17A6,JPH3" Drug 7250_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ALAD,CDC42BPA,SHROOM2,ARRB2,ADAM23,CFLAR,LDLRAD4,CACNA2D2,CHRNB2,RAB28,CRY2,PPP6R2,FAM131B,ARHGAP24,DLG3,DSCAM,DTNA,EGFR,SORBS3,IRAK4,DMTN,KIAA1109,FGF13,BAIAP2,TRMO,CSPG5,MSL3,BTN2A1,NFYA,NUMA1,SLC25A23,STRN3,PPP5C,WDR25,PEX5,RAB3A,ZDHHC14,GTDC1,ATXN7,PEX26,TNIK,SPTB,IQSEC2,FCHO1,SEPT8,CEP68,ASTN2,MTMR14,CHST5,WIPF1,NDRG4,NT5M" Drug 223_DN TTNPB; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ALK,CDC42BPA,APBA2,MYRF,P2RX6,REPS2,CHRNB2,LHX2,CLCN4,CLIP3,AATK,FEZ2,GREB1,ECE2,KLHL3,SIDT2,EFNA3,EFNB3,EIF4G2,MRNIP,EFEMP1,CAMSAP1,SCARA3,TRMO,FYB1,GNAL,ATF7,NXPH3,KCNK1,KHK,LAMA2,MYO7A,MYT1,PCDH9,MAPK3,PTHLH,BEND5,TCP11L1,EMID1,FERMT1,KDM4B,SON,TROVE2,PRRC2C,COBL,PARD3,TNS1,CADM1,PLPPR2,BEST1,ZNF32,MPPE1" Drug 1021_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC1,APAF1,APP,MARCH3,CACNA1D,CAMK2G,KYAT1,SOCS6,FAM189A2,TENM4,LRIG1,PDE4DIP,ARHGEF4,MAML1,KBTBD11,TRAPPC9,DTNA,TSPAN5,EFNB3,EGR3,OLFM1,TMEM164,EFCAB2,B4GALNT1,COPS8,BTN2A1,HNMT,JAK2,MPP2,NOS1,PCBP3,SETD4,CNNM2,RALGDS,RET,RGS3,TRAPPC13,SGK1,SYBU,KIF13A,KDM4B,IQSEC2,TSPYL2,THSD1,ST5,TTBK2,AJAP1,ATP11A,CHST8,ZNF34,SLC30A3,NAV2" Drug 7477_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "MRTFA,DOC2A,CDK13,CACNA1D,CALB2,CBFA2T2,CREM,GIT2,MFAP3L,MAGI2,DNM1,EFNB3,CELSR3,MRNIP,ERCC2,DENND4A,FECH,FGF12,BAIAP2,SEMA4D,GPR153,B4GALNT1,ALDH1L1,RAB30,GNAS,GRB10,RNFT2,ICA1,IL6R,KCNH2,KCNN1,LMO2,MAPT,ZNF862,SERPINE2,RETREG1,PLXNB1,GON4L,RIPOR1,CEP97,GSTCD,PAQR6,SLC11A1,ZCCHC24,MAPK8IP3,VPS13A,COBL,KIAA0930,DICER1,ZNF34,TMOD1,VLDLR" Drug 7436_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "NDRG3,KIDINS220,APOC1,PPFIA3,NCOA1,SYNJ2,PLEKHB1,B4GALT6,STOML1,TMEM184B,LRIG1,KIAA0586,DNM2,GNE,SUGP2,IRAK4,STX2,CGREF1,FYN,SRCAP,GRB10,MIA2,SLC25A23,PLXNB1,RETREG2,PPP3CC,PRODH,RALGDS,ZCWPW1,RGS10,SEC61A2,FBXW7,FBXO11,ABLIM3,ZNF365,SLC20A2,ZKSCAN3,ZHX3,ZBTB43,TROVE2,NCDN,PHLDB1,MTCL1,AHCYL2,KAT6B,CABIN1,TRIO,TRPC1,ZNF45,ZNF184,SMIM8,GAN" Drug 5358_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AP2A2,AK2,PPP4R4,DNAH17,MARK4,ATP6V0A1,CFLAR,KSR1,SYNJ2,SCARB1,SLIT2,CSF1,MAML1,SPOCK2,DNM1,SEZ6L2,SH3GLB1,DMTN,LRRC23,NCALD,CDKL3,DLC1,KAT8,ZNF589,BAIAP2,INPP5K,SLC2A6,ELOVL5,KCNMA1,MAP4,MOBP,PPP2R2B,PLPPR1,ZFHX4,FBXW7,SH3BP2,SLC1A7,PEX26,SLC20A2,UNC5B,SS18,TBL1X,CRTC1,SLC44A1,FAM155A,KCNK12,XRCC4,NDRG4,TFIP11,EVI5,GDPD5,UBE3B" Drug 4490_DN Piretanide [55837-27-9]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "C1QTNF1,ALK,MRTFA,PDE8B,MARK4,SLC4A4,ADGRB2,SCAPER,ARHGEF1,LY86,NRG2,LYPD1,AK5,SIDT2,EFNA3,DMTN,EPHA5,ANKMY1,SCARA3,GABRA2,GAD1,GAD2,TMEM8B,DISC1,C1QL1,KCNMB4,GNG4,TDRKH,IL11RA,KIFC3,MAPT,ZNF862,NDUFA5,OPCML,MAPK3,PTN,PID1,RGS7,SELL,SLC1A7,BTBD7,SNCA,SPTB,SYT11,SYN2,KAZN,WSCD1,TEX15,TMOD1,R3HDM1,TFIP11,UBE3B" Drug 6936_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ANK3,ARNTL,STX16,BCL7A,HIP1R,LRRFIP1,NMT2,HOMER3,ABCG1,FBXL5,DLG3,SIDT2,PHF20L1,IRAK4,CGREF1,MPP6,INPP5K,GOLGB1,GPR19,GRM8,HNMT,HSF2,KCNF1,KCNJ3,KHK,KIF2A,IPO5,MAP4,LYRM9,NF1,SETD4,OCRL,PPP3CC,PRODH,TMEM231,SH3BP2,ITSN1,SYBU,SMTN,ZKSCAN3,CDK5RAP2,SEMA4A,SIN3B,TRIM2,TNS2,ZMYND8,VGF,LMF1,NDRG4,MAP3K12,EPM2A,RNF146" Drug 3641_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "NME5,BIN1,RASL11B,CLGN,PLAA,CLU,STOML1,AKAP6,SH2B1,SNCAIP,CNTNAP2,RIMS2,RIMS3,DMPK,PLXNC1,ELN,NCALD,CEND1,ZNF589,FER,FOXG1,PDLIM5,DLL3,TMEM8B,GCNT2,GNAS,GRM8,KLF12,KCNK2,KCNMA1,SMAD1,KITLG,ADAM22,NF1,NNAT,NOS1,PRKCB,PRPH,EMID1,ASAP3,SLC2A5,SMARCD3,ZCCHC24,SPTB,ST5,VPS13A,EXOC7,DOCK9,SLC35G2,TRPM2,WIPF1,ADAMTSL3" Drug 4357_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC1,AP2A2,AK2,SEMA6A,AMT,SLC2A11,SYNJ1,SYNJ2,CA4,CA12,HAP1,CAMK2G,KYAT1,CHRNB2,PICK1,CSF1,MAML1,DAPK3,EFNA3,EFNB3,MBNL2,ZNF589,SCARA3,FOXG1,IQCG,GAD1,KCNH2,MBD1,MMP16,LYRM9,NDUFA5,RETREG1,SLC25A23,PMS2,PTCH1,TMEM231,RAB3IL1,RNASEL,FBXW7,RPS6KA2,RASA3,FBXO11,FAM214B,NXT2,NCDN,TTBK2,WSCD1,HEY2,BEX4,METTL3,CADM1,EPM2A" Drug 6634_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "CDC42BPA,CNTNAP1,APC,CDC14B,MARK4,ALDH4A1,ST3GAL5,ARHGEF2,REPS2,LARGE1,PLEKHB1,COL9A2,CPS1,CREM,SH2B1,HINFP,NCOR2,PDE4DIP,DZIP3,CTIF,DNAJC6,SGSM2,EXOG,COQ7,ETV1,C1orf61,SEMA4D,FYN,B4GALNT1,ERAP1,POLL,GPR37,GRK4,ITGA7,MDFI,ODF2,PFKFB2,GON4L,CNTLN,RGS10,ZFP30,BCAN,SLC1A7,WDTC1,SPTAN1,MAPK8IP3,SYT11,TIAM1,TPM2,KLC2,NAV3,MPPE1" Drug 6516_UP Tiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "NME5,PLA2G6,ALDH4A1,CADM3,ADAM23,RGS9,NEURL1,VCAN,RASSF2,BRINP1,HP1BP3,RCAN1,DTNA,HEYL,LRRC23,F5,CORO2B,ST3GAL6,FYB1,GNAS,LPAR4,KLF12,ITGA7,ITIH2,KCND3,KCNN1,MGAT3,NF1,PDE4B,RETREG1,PMP2,PROX1,SAMD9,PTAFR,PEX5,RNASE1,SBF1,FRMPD1,FAM214B,SLC11A1,RBM26,PLCB1,ARC,SMG6,PCDHA5,VIPR2,WIPF1,ZNF711,PRDM2,SEMA3B,KCNAB1,AAAS" Drug 61_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC1,NDRG3,GAS7,PPFIA3,CHRD,CACNA1A,CAMK2B,CHN1,CHRM4,NCOR2,ECE2,DCT,ATN1,DNAJB6,EPHB1,OLFM1,FGF12,BAIAP2,SEC23B,ADAMTS13,GRM1,NCKAP1L,SYNPO,KCNB1,KCNJ10,KCNN1,KIF5A,L1CAM,MBNL1,MMP17,MYT1,NELL2,CDK18,PDE1C,CDK14,PLCD1,PAQR6,AMBRA1,PEX26,PKNOX2,SLC11A1,KBTBD4,SON,AJAP1,TBL1X,KCTD2,PARD3,TNR,SEZ6L,TRIO,PLPPR2,VIPR2" Drug 1542_DN Paclitaxel [33069-62-4]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "PPFIA3,CDK5R1,BTRC,CAMK2G,RIMS3,SMG7,TMCC2,DNM1,RCAN1,IRAK4,COQ7,ANKMY1,FER,BAIAP2,FAM49B,INPP5K,GLYR1,RAB30,GLS,GNG4,INPP5B,MBD1,NASP,NEK1,NFYA,NUMA1,MBOAT7,FSD1,APTX,RGS12,ROM1,FAM192A,ZNF821,FBXO11,SLC1A7,PPP4R3A,EPN2,ZCCHC24,ZBTB43,POGZ,PLCB1,KAZN,SEMA4A,AP4E1,ZNF34,TMOD1,SPHK2,REEP1,NAV2,WIPF2,EPM2A,ST7" Drug 2257_UP Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AP2A2,NME5,PLA2G6,BRINP2,ADAM23,CFAP410,CACNG1,ZMYM4,DNAJB5,COL9A3,CSF1R,CNTNAP2,PPP1R16B,ARHGAP24,CTIF,DSCAM,ABCC9,HIPK3,ELN,RASGRP2,SPEG,TUBB4A,CAMSAP1,FOLR2,GAB1,GLYR1,GLS,LILRA2,GPER1,GRIK1,GRM7,HLF,ITIH2,MBNL1,MDFI,MOBP,CD200,NTRK2,PFKFB2,CCDC40,GAL3ST4,TMEM206,RPS6KA2,FRMPD1,ASAP3,SNAP25,WSCD1,ZEB1,HEY2,TRPC1,MVB12B,SMIM8" Drug 1890_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ARID1A,APBB2,ARHGAP5,KRIT1,CDC27,QKI,FBXL5,DDX46,ACOT8,MAMLD1,KCTD3,SORBS3,EPB41L2,FGFR1,SEC23B,NCKAP1,GLS,GRIK5,CLASRP,MAP4K5,LAMP2,MKLN1,NRGN,NUCB2,OPA1,PDE1C,POLG,EXD2,WLS,CASC3,FBXO11,ABLIM3,SLC11A1,SHANK2,SLC22A4,ZKSCAN3,DOP1A,PEG10,ATP10B,EPB41L3,LARP4,DIP2A,VAMP1,TBL1X,DOCK9,DICER1,TPM4,HIRA,UBE2H,CLDND1,EVI5,MARCH8" Drug 5485_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC1,LTBP4,APLP1,ATP2B2,N4BP2L1,LDLRAD4,HAP1,CAMK2B,CHI3L2,PLEKHB1,NCOR2,DRD1,LRRC23,STX2,REEP2,TPK1,TBR1,GLS,GNAO1,CNTRL,TJAP1,KCND3,KCNQ3,SMAD1,AFDN,ZNF862,NPY,NRGN,NUCB1,P2RY1,ENPP2,PURG,PRKCB,WDR25,RIPOR1,RAD52,KCNIP1,SH3BP2,SLC1A2,LIMS2,PKNOX2,ELMO2,SLN,KDM4B,HECW1,RGL1,SYT5,SEMA4A,DAAM2,TRO,MICAL1,FTSJ1" Drug 5395_UP Aminophylline [317-34-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADRA1D,PLA2G6,LTBP4,ALK,BEGAIN,CDC14B,MPDZ,ST3GAL5,CDK5R2,CAMK2G,CDC42,CHN2,WHRN,GREB1,RIMS2,DTNA,DTNB,EGR3,TENM1,COQ7,FHL1,GABRA2,HBS1L,C1QL1,GLS,PRRC2B,GPM6A,GRM1,HLF,KPNA5,MID1,MYT1,NNAT,NTRK2,PENK,MTRF1L,MAPK10,PTHLH,SLC1A7,PKNOX2,SHANK2,DOK5,ATP10B,ZC4H2,VPS13A,TAC3,SMG6,TCF4,LAT2,ZIC3,SPHK2,ADAMTSL3" Drug 1790_UP Folic acid [59-30-3]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "PPFIA1,SHROOM2,N4BP2L1,CA12,HIP1R,CLDN10,KYAT1,FAM189A2,TMEM184B,IQCK,PPP6R2,DCTN1,HP1BP3,MBNL2,EGR3,RASGRP2,CAMSAP1,TRMO,POMT1,GAP43,ALDH1L1,GNAS,ACOT7,KIF5A,KIF5C,KLC1,NFYA,NOS1,NPPA,ODF2,PLCB2,CNNM2,DEF8,BSDC1,RGS10,RGS12,SEC61A2,ZNF671,NTNG1,SLC11A1,ELMO2,KDM4B,FAM208A,TCF4,TNR,GORASP1,VIPR2,CLIP2,TRIM9,PRDM2,URM1,SLC17A7" Drug 5858_UP Delsoline [509-18-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "SYN3,ACHE,NME5,SPARCL1,BIN1,EPB41L5,PPP4R4,SYNJ2,MAP7,CDH8,ASIC3,DNAJB5,COL9A3,BRINP1,SRGAP3,RCAN1,CNNM1,FAM13A,RASGRP2,FAM198B,KIAA1109,FGF1,SCARA3,IQCG,DKK3,TRAF3IP2,ALDH1L1,GNAO1,LILRA2,LPAR4,GPR37,SCIN,KCNA1,KCND3,KCNMA1,MATN3,MDFI,MEF2C,PPARA,PTPRD,BEND5,FBXW7,TCP11L1,RYR1,SNCA,WDTC1,TMEM121,TLL2,SEZ6L,ZNF74,SPHK2,DPF3" Drug 6062_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AP2A2,C1QTNF3,PPP4R4,ASPH,ATP6V0A1,SCAPER,CACNA1D,ARHGEF2,CDH10,ARHGAP33,CHRNB2,PICK1,CNTFR,AKAP7,BAG4,CSF1,DRD1,PLXNC1,ELN,EN2,VPS13B,ATP8A1,KIAA1109,CAMSAP1,FOXG1,GAD1,RND1,GPR75,GLS,GRIK5,GRM1,HNMT,KPNA5,MAP2,MATK,MMP16,ADAM22,NNAT,SNTG1,SLC25A23,RPS6KA2,WLS,ASAP3,COA1,HECW1,PHLDB1,PLCB1,RPGRIP1L,CHST8,TUBB1,WIPF1,PLSCR4" Drug 2882_DN Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABHD6,SLC12A5,BCAS1,RASL11B,ATP6V0A1,BCL2L2,SYNJ2,CFAP410,ARHGEF1,AKAP7,FAM169A,PHF14,DBN1,OPTN,ING4,LRRC23,F3,SCML2,ZNF589,FECH,FHL1,GPR153,HBS1L,DISC1,IGSF1,PAXBP1,MAP4,MAPT,GIT1,PLXNB1,GON4L,RGS10,RGS12,FBXW7,SBF1,BCAN,PEX26,KDM4B,SOX2,ZHX3,EMC1,THSD1,MAPK8IP3,TTBK2,EXOC7,TK2,TMOD1,RBFOX2,TPM1,ZMYND8,ZNF142,WIPF2" Drug 3800_DN Cyclacillin [3485-14-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADCY2,ALK,SEMA7A,KCNAB2,APC,CDK10,SEMA4G,RASL11B,SLC4A4,BMP7,CACNA2D2,EPS15L1,CLCN4,PICK1,CSNK1E,RIMS2,PARD6A,EXOG,DTNA,SIDT2,GNAS,GNG4,HSF2,ITGA7,JAK2,LAMA2,NPR2,PPARA,MINDY2,RGS10,KCTD17,SELL,BCAN,RPH3A,PREX2,LIMS2,ARHGEF40,SLC9A5,ZNF334,WDTC1,ARHGAP26,LHPP,THSD1,ELOVL4,SYNE1,BHLHB9,TNS1,TRIO,VIPR2,KLC2,ZNF74,SH3GLB2" Drug 6515_UP Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADORA2A,AK2,MRTFA,BRINP2,ATP2B3,CADM3,CACNA2D1,CAMK2A,SCARB1,TAOK2,ZFYVE9,QKI,AKAP7,PCYT1B,SH2B1,VCAN,GREB1,ARHGEF4,SPOCK2,KBTBD11,ST8SIA3,EFNB3,AASS,FGF13,FHL1,PRELID3A,TBR1,OGA,GAP43,SEPT9,GPD2,GPER1,GRIK2,NR3C1,GSTM5,HPCA,MAOB,MMP16,MSI1,ADAM22,MX1,CNOT4,CAMKV,PLCD1,TCP11L1,ST6GAL1,EXOC7,NSD2,XRCC4,ADAMTS9,KCNAB1,PLSCR4" Drug 3684_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASPHD1,ADD2,LTBP4,MRTFA,BIN1,APAF1,ARRB2,SYNJ2,CBS,ARHGEF1,SEPT7,B4GALT6,AKAP7,IFFO1,SH2B1,NCOR2,EDRF1,DCAF8,CDON,DTNA,LRRC23,GABRA2,TRAF3IP2,GAD2,SESN1,PCDH17,MSL3,POLL,CNTRL,HSD17B1,KIFC3,ADAM22,NF1,OPRL1,PDE4D,PLPPR1,PTN,PTPRB,CCDC40,ZCWPW1,RPS6KA2,ATXN2,MRAS,PREX2,ZNF667,ARHGAP26,SS18,ZMYND8,VLDLR,ZBTB14,MAP3K12,TIGD6" Drug 7524_DN Suramin sodium salt; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASPHD1,MTUS1,C1QTNF3,ALCAM,APLP1,ATP2A2,RIPK1,CFLAR,GYG2,CA4,ARHGEF1,NCOR2,LRIG1,NOS1AP,DBT,DLG3,DTNA,FGFR1,PRKAG2,FOXF2,ANKFY1,DPYSL4,FAM49B,GAB1,HBS1L,MAP4K5,MPP2,ADAM22,NFYA,NNAT,PLEC,PLTP,PPP3CC,PRPH,SBF1,TRA2B,PPP4R3A,SLC20A2,ZCCHC24,KDM4C,UNC5B,CLASP2,ITPRID2,VPS13A,KIAA0930,PSD3,PARD3,CHST5,VAV2,VLDLR,ZNF24,EMSY" Drug 5476_UP Torsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "CDC42BPA,SEMA4G,ARRB1,NCOA1,ALDH7A1,NRP2,GYG2,LDLRAD4,HAP1,RCHY1,CSF1,CSF1R,VCAN,CNTNAP2,MED12,CALCRL,FGF1,FLNC,EFCAB2,PDLIM5,PRELID3A,FUT9,GAB1,GCNT2,ADAM28,LYVE1,CACFD1,GUCY1B1,IGSF1,INPP5B,KIFC3,LAMA2,LMO2,SMAD1,MSR1,NPY,LRP12,RPS6KA2,KCNIP1,KDM4B,ZC3H13,BEX1,INKA2,SYN2,CRTC1,AMACR,TRPC1,ZMYND8,NSD2,ZIC3,SLC30A3,PRDM2" Drug 3101_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ALK,CDC42BPA,EPB41L5,DNAH17,BMP7,BAIAP3,CACNG1,THSD7A,RUNX1T1,KCNAB3,TAOK2,NRXN1,SLC24A2,KIAA0513,SPOCK2,DLG4,DMPK,DSCAM,SORBS3,ELAVL4,HSD17B14,ETV1,C1orf61,GLI2,GNAO1,GRIK2,KIF3A,GUCY1A2,KCND1,NHLH1,NPPA,PRKAR1B,MASP1,RELN,LRRC49,PTPRN2,FAM120C,PNMA8A,ROM1,EMID1,SLC30A10,KDM4D,SLN,CXXC4,PALLD,PCDHGB6,DOCK9,TNS1,SEZ6L,TRPC1,FAM155A,NAV2" Drug 6186_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADCYAP1R1,ALK,LGR5,PDE8B,CACNA1I,BAIAP3,CACNG1,NEURL1,CDH10,CHGB,PCYT1B,RGS6,PDE4DIP,DAPK3,PARD6A,DLG3,ATN1,SORBS3,TENM1,LRRC23,TBC1D16,FER,FGFR1,BAIAP2,C1orf61,RAB30,PCSK1N,PCLO,ICA1,KCNH1,KCNJ3,KCNN1,SLCO1C1,NNAT,PDE4A,TMOD2,SERPINI1,FSD1,PROX1,RPS20,SCG5,SLCO1A2,SOX10,IZUMO4,RAP1GAP2,PCDHGA1,TEK,RUNDC3B,AMACR,RPRM,KCNK12,KCNAB1" Drug 2399_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABHD6,AP2A2,PKP4,LGR5,ARHGDIG,ARRB1,ATP6V0A1,BMP7,CALB1,KALRN,HIP1R,CDH8,CHRNA4,ZFYVE9,COL9A2,SLC4A8,PPP1R16B,CTNND1,RIMS3,EDN3,EIF4G2,DMTN,NCALD,FABP7,CAMSAP1,PDLIM5,KHDRBS3,INPP5K,DIDO1,GRIK5,CACFD1,ICA1,KIT,PPARA,PRKCZ,MAPK7,PTAFR,NKAIN1,RAB3IL1,RGS3,ASIC4,FAIM2,PALLD,SP4,TROVE2,SS18,PDLIM2,CRTC1,TJP1,TRPS1,GDPD5,KCNAB1" Drug 7336_UP Letrozole [112809-51-5]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "CDC42BPA,GAS7,CDK10,ARHGDIG,MARK4,CFLAR,CAMK2B,USP2,ARHGEF1,CBARP,CHM,LY86,SIPA1L1,RIMS3,DNAJC6,MED24,MAGI2,TNK2,EZH1,ZNF589,SEMA6C,GAD1,SRCAP,RND1,GNG4,ELOVL5,ICA1,TJAP1,SMAD1,MGAT3,ADAM22,NF1,CNOT4,NOVA2,PALM,MAPK7,GON4L,SNRK,ZSCAN32,RAD51D,RAD52,URGCP,WDTC1,ZCCHC24,ZHX3,CAND2,ZC3H13,EXOC7,CRTC1,ZNF34,HEY1,PRDM2" Drug 2071_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "DPF1,ADGRF5,CNTNAP1,APBB2,ADAM15,MYRF,LDLRAD4,ARHGEF1,TBRG4,PLEKHB1,NMT2,DNAJB5,AKAP7,COL9A3,AKAP5,BAG4,CRY2,DAPK3,GIT2,HP1BP3,DLG3,EFNA3,IRAK4,EN2,TUBD1,PLEKHO1,VPS26C,ZNF589,STON1,KIFC3,PDE4B,PIK3CD,PLEC,MAPK8,SIDT1,PTPRH,RIPOR1,RAB3IL1,FAM184A,FBXW7,SLC6A8,SLC22A4,ZNF415,SS18,SYT11,SZT2,ZNF34,SSBP2,NSD2,SPHK2,LRP8,UBE3B" Drug 3207_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ARID1A,APC,APP,AQP4,ATP2A2,ALDH7A1,ATP6V0A1,LDLRAD4,CBFA2T2,TAOK2,RCHY1,CPS1,AATK,VCAN,RASSF2,BRINP1,DUSP9,ING4,EFS,ATP8A1,FGF12,FHL1,IQCG,SORBS1,GABRA2,GPR75,AFDN,NEUROD2,DDR2,CLDN11,PAH,PAX6,PLEC,PPP5C,GRAMD1C,ROM1,SYNDIG1,RASA3,SMTN,SLC6A8,CXXC4,SOX15,ZHX3,ACSBG1,TCF7L2,TRIM2,TK2,HEY2,R3HDM1,TPM2,TPM3,DNALI1" Drug 6240_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ARID1A,TRMT9B,GAS7,APLP1,APOC1,ADAM23,AZGP1,BAIAP3,CACNA1D,SCARB1,NEURL1,DLGAP1,FOXN3,ZFYVE9,PLAA,CLCN3,RIMS3,DBN1,SGSM2,CDON,ING4,PIPOX,F3,GABRA2,GNG3,PRUNE2,TDRKH,LPAR4,GRK4,GRIK5,ADAMTS8,KCND3,KCNH2,MPP2,KCNK10,SNX10,LRP12,PRPH,FAM120C,RAB3A,RGS10,SLC11A1,SOX2,HECW1,ZBTB43,PBLD,MAPK8IP3,SEMA4A,HIRA,VIPR2,REEP1,NUP214" Drug 5436_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "DPF1,ACTN2,ADORA1,BIN1,CDC42BPA,SEMA7A,APBA2,SEMA4G,PLA2G4C,AZGP1,SYNJ1,CDH2,SOCS6,VAX2,CREM,DBT,MFAP3L,SPOCK3,SLC12A6,DRD1,HIPK3,EGFR,AASS,STX2,EFS,PDLIM5,LYVE1,RUNDC3A,GLS,MCHR1,GRK4,NR3C1,KIT,MAP4,MOBP,ADAM22,TAGLN3,PCDH9,PLTP,RAB3IL1,FBXO11,ANKRD6,SLC1A7,FAM214B,SNCA,ZCCHC24,KIF21B,ZC3H13,UCHL1,ZIC3,SYNC,SCG2" Drug 5769_DN Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ACTN1,ADRA1D,ADRB2,APBB2,APC,PPFIA3,BCL7A,ABI3BP,CREM,CSF1,SDC3,RUBCN,DCAF8,RIMS3,RUSC2,C2CD2L,SPOCK3,DPH1,HIPK3,OPTN,C3orf18,SPEG,FGFR1,SCARA3,IQCG,GBX2,SRCAP,TDRKH,TJAP1,KIF2A,LYRM9,NF1,NPR2,PFKFB2,POU3F2,MINDY2,PPP5C,RGS10,TTLL7,SUGCT,ASAP3,FUZ,ZHX3,BEX1,DDN,SZT2,DNAH7,TIAM1,TNS1,HIRA,UGT8,KCNAB1" Drug 4962_UP Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASIC2,ADCY2,ADORA1,NME5,SEMA6A,ALK,FAM131A,BRINP2,ATP2B3,ARHGAP33,FOXN3,DNAJB5,CNTN1,ARMC8,CTH,DLG3,DRD1,HIPK3,SIDT2,ELAVL3,ELN,APC2,CEND1,DLC1,KIAA1109,SCARA3,TPK1,FYB1,GNG4,GPM6B,NF1,RETREG1,MTRF1L,PTPRO,MYH14,CNKSR2,PKNOX2,SNCA,KIF13A,WDTC1,ZHX3,ZBTB43,RGL1,SYN2,POPDC3,TK2,CABIN1,PIK3R5,LILRA4,TRIO,SLC17A7,KCNAB1" Drug 2320_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "C1QTNF3,MRTFA,CDC14B,MARCH3,MARK4,ST3GAL5,ARHGEF1,SCARB1,TAOK2,DNAJB5,SIPA1L1,DZIP3,EDRF1,LYPD1,EFNB3,SORBS3,ZNF589,FHL1,TXNL4A,MSL3,PRRC2B,TDRKH,GRIK5,NR3C1,GRM7,GSN,ATXN2L,KCNN1,VWA5A,ZNF862,NRGN,CDK18,SLC25A23,PPP2R2B,ELOVL2,SBF1,FNDC3A,FAM214B,WDTC1,ZCCHC24,SPTAN1,SEMA4A,EXOC7,KIAA1107,TRIM2,TNS2,CRTC1,PARD3,PLPPR2,GDPD5,SEMA3B,KAT6A" Drug 6469_UP Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "CDK13,ASCL1,BRINP2,ATP1A2,N4BP2L1,C5,KALRN,NEURL1,CHI3L2,FADS2,WHRN,CABP1,SLC4A7,SH2B1,CRMP1,LRIG1,ARHGEF10,VCAN,EDRF1,EDNRB,EFNB3,EGR3,EIF4G2,DLC1,FOXG1,FYB1,GAD2,INPP5K,GRB10,IL6R,ITGA7,KIF5C,BCO1,OPRL1,PDGFRA,ENPP2,PLEC,MAPK7,PTHLH,C1orf54,RGS12,RYR1,ASAP3,SYBU,UNC5B,PHLDB1,EXOC7,PCDHGB6,TRPC1,ZNF711,PLSCR4,SSPN" Drug 4337_UP Proglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASPHD1,ASIC1,ALK,PKP4,APAF1,RASL11B,ATM,KIF1A,BMPR1B,CACNA1I,KALRN,HAP1,CAMK2B,CHRNB2,DNAJB5,IFFO1,NCOR2,CNTNAP2,SPOCK2,RABGAP1L,STX2,OLFM1,FGFR1,CAMSAP1,FERMT2,ATF7,GPR17,ITPKA,MAP4,NOVA2,NPTX2,NRCAM,NTRK2,NUMA1,SNTG1,RETREG1,C19orf57,ACSS3,RASGRF1,RGS4,TMEM206,SCNN1D,MRAS,SLC15A2,ZSWIM8,LMO3,EXOC7,DICER1,CHST5,CA14,UCHL1,LAT2" Drug 3531_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AP2A2,AK2,C1QTNF3,BIN1,PPFIA3,MARK4,ATM,CFLAR,SCAPER,BTRC,SYNGR3,MAGI1,VAX2,MAML1,RUSC2,SMG7,G3BP2,OPTN,EFNA3,RACK1,ANKFY1,GAB1,IL6ST,MBD1,MPP2,GIT1,NPTX1,RAD52,SLC25A36,SH3BP2,ASAP3,FNDC3A,ANKRD6,ZNF365,SLC6A8,SLC22A4,KDM4B,ZHX3,EMC1,UNC5B,ZBTB43,PHLDB1,STX1A,EXOC7,SLC44A1,TMOD1,CABIN1,ZKSCAN5,HIRA,ZNF74,MAP3K12,SSPN" Drug 3036_UP Aminophylline [317-34-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "CDC42BPA,ATP1A2,FUBP1,HAP1,SOCS6,STOML1,AATK,CNTNAP2,RIPOR2,DCC,C2CD2L,ARNT2,ATN1,EGFR,EPB41,B3GAT1,SIGLEC8,ZNF276,GNAL,LILRA2,PCLO,GUCY1A1,PTGDR2,KLF12,SCRG1,KIF5C,CD200,NPY,KCNK10,PDE1C,POU6F1,MAPK10,CNNM2,ACSM5,MAP6D1,PREX2,TMCC1,KDM4B,IZUMO4,PEG10,CDK19,NCDN,TACR1,SMG6,ATP13A2,ZFPM2,CRB1,ZNF34,LMF1,SLC13A3,KCNK12,STMN4" Drug 365_DN "estradiol, USP; Down 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "BIN1,APBB1,LDLRAD4,HAP1,DLGAP1,LHX2,CLCN4,TPP1,TCEAL2,CPS1,HINFP,ARHGEF10,OSBPL3,ECE2,KLHL3,RCAN1,SORBS3,ELN,FABP7,ZIC4,FGFR3,FAM49B,OGA,GAB1,DENND2A,GFAP,LUZP2,IL6R,KCNJ5,KCNMA1,MAOB,STRN3,PPP2R2B,CEP41,PRKCZ,KLHL11,KLHDC8A,ATXN1,ST6GAL1,SLC9A5,KBTBD4,UHRF1BP1L,NPAS3,ZC4H2,ADGRL3,TBL1X,TCF7,TLL2,TPM1,TMPRSS5,SSBP2,AAAS" Drug 7437_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ASPHD1,DGKD,NCOA1,ATM,CFLAR,SRSF11,ZFYVE9,CSNK1E,GREB1,EDRF1,INTS1,SGSM2,DLG3,MAMLD1,EGR3,PLEKHA1,EFCAB2,TRAF3IP2,GRB10,ATXN2L,IPO5,MBP,MEIS2,NEK1,ODF2,OGDH,PCDH9,KCTD15,PLEC,POLG,PPP2R5C,PRKAR1B,CEP97,SBF1,GALNT10,SH3BP2,FBXO11,FNDC3A,PEX26,BTBD7,TSPYL2,POGZ,MAPK8IP3,PHLDB1,PSD3,KCTD2,METTL3,TRIO,VAV1,UPF3A,HPS4,MPPE1" Drug 4459_UP genistein; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADORA3,SPARCL1,SLC4A4,ADGRB1,FUBP1,CAMK2B,CCNT1,TPP1,STOML1,LY86,ERC2,RIMS2,CHRDL1,TUBB4A,KIAA1109,BAIAP2,FOXG1,GAP43,ALDH1L1,IRAK3,ITGA7,KCNF1,LMO2,NELL2,SLCO1C1,PDE2A,PDE4B,PDGFRA,ENPP2,CEP41,PRPH,PTPRN2,KHDRBS2,RGS3,RNASEL,KIRREL1,TCP11L1,KCNIP1,FRMPD1,PREX2,KANSL3,SLC8A1,SLC11A1,KIF21B,SP4,PLCB1,TAC3,KLHL4,CRTC1,THRA,LAT2,NLRP3" Drug 6212_UP Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "APOC1,ALDH4A1,SCAPER,MTMR3,CACNA1I,TAOK2,ZFYVE9,PLAA,HOMER3,FAM149A,CSF1R,PDE4DIP,BRINP1,KBTBD11,ATN1,EDN3,MBNL2,SORBS3,MTSS1L,DENND4A,F8,GCNT2,GNG3,GRB10,GRM8,BTN2A1,RNFT2,KIF2A,MAP4,MGAT3,MPP2,NNAT,PDE3B,SLC25A23,MED1,PPP2R2B,MAPK7,PRPH,SH3BP2,ABLIM3,SNCA,ZHX3,IZUMO4,CEP68,SYN2,SEMA4A,IQCE,KIAA0930,TRIM2,AP4E1,AMACR,NUP214" Drug 2359_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "FZD9,PLA2G6,APBB2,DNAH17,KIF1A,RGS9,KSR1,SYNJ2,MTMR3,CACNA2D1,CAMK2A,CDC42,MAGI1,AKAP7,SLITRK5,PPP1R16B,SGSM2,ST8SIA3,SIDT2,EFNB3,AASS,CDHR1,F5,FOXG1,DKK3,MAPT,MGAT3,MYCN,NEFM,NF1,NTRK3,ENPP2,NLE1,PPARA,PTPRO,RAP1GAP,RGS3,MYH14,MRAS,ASAP3,SNAP25,RBM34,SOX2,SPTAN1,KIF1B,ZBTB43,FAM168A,VAMP1,SYT5,TPM1,CLIP2,STMN4" Drug 3563_DN Estriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADCY6,BRAP,DOC2A,PPFIA3,CDK10,BCL7A,CFLAR,GYG2,SOCS6,AKAP7,SOCS5,GIT2,ZNF804A,MFAP3L,DNM1,DSCAM,ING4,CDKL3,TPK1,CNTRL,INPP5B,MBD1,MPP2,NEK1,NF1,NRGN,NUMA1,OGG1,PC,PLXNB1,MBOAT7,MINDY2,PRPH,RAB3A,ZNF821,SH3BP2,AMBRA1,SMTN,CCDC88A,SHANK2,SLC20A2,CDK5RAP2,KDM4B,ZHX3,SS18,ST5,SMG6,AP4E1,CABIN1,RBFOX2,MICAL1,GDPD5" Drug 6790_UP Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "RALGAPA1,C1QTNF3,APOC1,ADAM23,ADGRB3,CBFA2T2,NEURL1,SRSF11,NCAN,CTIF,JAKMIP2,RUSC2,TMCC2,DYRK1A,EFNA3,EFNB3,HSD17B14,F5,ZNF589,GPR153,FYB1,ALDH1L1,GFER,GNAL,LPAR4,CNTRL,CACFD1,GRM1,HRH3,HNMT,JAK2,KCNJ5,ADAM22,NDUFA5,NF1,PDE4A,PIK3CD,EPN1,MAPK7,LRRC49,RAD52,MYH14,SCG5,SLC14A1,VPS13A,TAL1,SMG6,THRA,CABIN1,LAT2,HPS4,ST7" Drug 7216_UP Repaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "AK2,SEMA6A,ALCAM,APBB2,APLP1,PPP4R4,RGS9,ST3GAL5,CAMK2B,CCKBR,ARHGEF1,CBFA2T2,NRXN2,STOML1,SDC3,ARHGEF4,RASSF2,EXOG,RASGRP2,CAMSAP1,IQCG,OGA,GFER,GLYR1,GPR37,GRM1,GRM8,GUCY1B1,KLF12,KCNH1,KIFC3,VWA5A,MITF,AFDN,MPP2,NDUFA5,PGAM2,PMP2,POU3F2,PPP3CC,PRKAR1B,PRODH,RGS10,RGS12,ASAP3,KDM4C,ZC3H13,TTBK2,ARC,CRTC1,TMOD1,SYNC" Drug 4383_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "KIAA1324,CDC14B,SEMA4G,BRINP2,SYNJ1,CACNA1I,HAP1,CAMK2B,ARHGAP33,CHRNB2,AATK,CSF1,CSF1R,DRD1,ERCC2,PTK2B,RND1,GRIK5,ICA1,KCNH2,KHK,KIFC3,TM6SF1,MID1,NTRK2,PDE3B,POU3F2,PPARA,MAPK10,ZSCAN32,RIPOR1,RAB3IL1,ZDHHC14,RGS12,RASA3,SLC1A7,SLC9A5,KIF13A,UNC5B,JMJD6,SZT2,CRTC1,SLC44A1,TMOD1,DAAM2,TRPM2,ZMYND8,VGF,VIPR2,KCNAB1,MVB12B,NUP214" Drug 1179_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "PKP4,APAF1,APBB2,BCL7A,SYNJ2,MAP7,ARHGEF1,NMT2,ARMC8,CREM,DZIP3,TM9SF4,FCF1,SUGP2,TUBD1,OLIG2,VPS13B,KAT8,ANKFY1,CAMKK2,CGREF1,ZMYND11,LPAR4,PTGDR2,KCNJ5,MEF2C,SCAMP5,NF1,CNOT4,PIK3CD,PLCD1,POLG,TRAPPC13,RASA3,ITSN1,PREX2,SLC11A1,SNCA,ZHX3,ZBTB43,THSD1,SYN2,SEMA4A,EXOC7,TCF4,SIN3B,CRTC1,TMOD1,TMPO,TPD52,HSPBP1,VLDLR" Drug 3741_DN Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ABR,ADGRF5,C1QTNF3,MRTFA,TRMT9B,PPFIA3,ADAM15,ADGRB2,ST3GAL5,BTRC,CACNB2,CAMK2B,LARGE1,CSNK1E,CNTNAP2,CTNND2,MAML1,PARD6A,SRGAP3,AK5,DTNA,FGFR1,C1orf61,PDLIM5,TRAF3IP2,GRIK2,CACFD1,GRM7,MAPT,NELL2,PC,PDE4A,PDE4B,PFKFB2,PIK3CD,RETREG1,CEP41,PTAFR,FAM120C,C1orf54,ZCWPW1,FOXRED2,MRAS,PPP4R3A,TSNAXIP1,SPTB,SZT2,TEX15,VGF,VIPR2,MVB12B,TIGD6" Drug 4628_UP Crotamiton [483-63-6]; Up 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "ADCY6,AP2A2,ADGRF5,BIN1,APBB1,GAS7,PPP4R4,N4BP2L1,NRP2,KSR1,KALRN,DLGAP1,VAX2,NRG2,MAGI2,DTNA,SIDT2,ZNF549,FYB1,TMEM8B,SIGLEC8,GNAL,GPR22,GSTM5,KCNA2,VWA5A,TAGLN3,LYRM9,NF1,RETREG1,NLE1,MTRF1L,POU6F1,RASGRF1,KCTD17,SELL,HKDC1,SLC4A3,RPH3A,KANSL3,ZHX3,ZNF423,BEX1,ARHGAP26,ACSBG1,SYN2,PCDHA5,TNS1,TPM3,TRPC3,VIPR2,MVB12B" Drug 5266_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-04 1.00E+00 1.11E-03 1.26E-02 52 199 "DPF1,NDRG2,NME5,LTBP4,FGD2,KCNAB2,ATM,CFAP410,USP2,CDH18,CLCN4,FADS2,COL9A3,PDE4DIP,MAML1,CTIF,EDN1,C3orf18,ERCC2,FABP7,OLFM1,SORBS1,GAD2,GATM,SRCAP,GNAO1,ADAMTS13,PTGDR2,TJAP1,KCNN1,KCNN2,SMAD1,ADAM22,NCF2,NTRK2,PLCB2,PTAFR,RPS6KA2,SEMA6D,SBF1,BCAN,SLC11A1,SMARCD3,POPDC3,EXOC7,DMXL2,ZEB1,SZT2,PCDHGA10,PIK3R5,FLRT2,NT5M" Drug CID000005355 sulpiride Stitch 1.06E-04 1.00E+00 1.11E-03 1.26E-02 30 96 "ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CCK,CCKBR,CHRM1,CNR1,DRD1,ABCC9,PPP1R1B,AGAP3,GAD1,GAD2,GPT2,GRIN2C,GRIN2D,HTR2A,NPY,OPRL1,PDYN,PENK,SLC22A4,SOX10,SST,TAC1,MLST8,TRH" Drug CID000000948 nitrous oxide Stitch 1.06E-04 1.00E+00 1.11E-03 1.26E-02 30 96 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1I,CBS,AP4M1,TRIM69,APPL1,TRAPPC9,AASS,ATP2C1,GGT7,GGT5,GUCY1B1,MBP,MTR,NBL1,OPRL1,PDYN,PENK,FXYD1,RDX,RYR1,TNFRSF19,ZNF365,TAB2,CLSTN2,TNFRSF1B,UBE2H" Drug CID000001299 AC1L1B62 Stitch 1.08E-04 1.00E+00 1.13E-03 1.29E-02 11 21 "F3,FOLH1,ATP6V1H,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3" Drug ctd:D003932 Heroin CTD 1.08E-04 1.00E+00 1.13E-03 1.29E-02 18 46 "ACTN2,AMPH,APP,SYNGR3,PREPL,PDE4DIP,BLOC1S6,SV2A,VTI1B,NTRK2,PDYN,SLC25A23,SEPT4,SNAP25,STXBP1,SYT1,ENHO,PMEPA1" Drug CID000107699 CGP 35348 Stitch 1.10E-04 1.00E+00 1.15E-03 1.31E-02 22 62 "ABAT,ADORA1,BSN,GPHN,CSPG5,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIK1,GRIN2C,GRIN2D,KCNJ3,PEG10,SST,MLST8,ZEB1" Drug 5584_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.13E-04 1.00E+00 1.18E-03 1.34E-02 48 180 "NDRG2,KIDINS220,AMT,APC,BRINP2,AZGP1,ST3GAL5,CA4,CLGN,CHI3L2,CHN2,ZFYVE9,CSF1R,GREB1,GIT2,EFNB3,MBNL2,EGR3,ING4,ELAVL3,EPHB1,ACSL4,OLFM1,B3GAT1,DISC1,GCNT2,GLYR1,PCLO,GRM7,ADAM22,NUMA1,MINDY2,MAPK10,GDPD2,PTAFR,ELOVL2,ST6GAL1,SYBU,PKNOX2,KDM4B,AJAP1,POPDC3,TRIM2,HEY2,RUNDC3B,VLDLR,WIPF1,SLC30A3" Drug CID000003836 AC1L1GTQ Stitch 1.13E-04 1.00E+00 1.18E-03 1.34E-02 20 54 "CACNA1B,CACNA1D,CAMK2B,CAMK2D,KRIT1,MYEF2,CAMKK2,GRIA1,KCNK3,MYBPC1,CAMKV,PRKCG,MAPK3,PTPRN2,PBRM1,RYR1,SNAP25,CABIN1,SLC13A3,CAMK1G" Drug CID000005556 triazolam Stitch 1.13E-04 1.00E+00 1.18E-03 1.34E-02 20 54 "CACNA2D1,TOX,DBI,AASS,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MALT1,ABCB1,PTAFR,CASC3,SST,NXT2,TST" Drug CID000000595 dl-cystine Stitch 1.13E-04 1.00E+00 1.19E-03 1.35E-02 37 128 "AGT,CASK,NFS1,CBS,MAGI1,CDO1,SLIT2,COL4A5,SMARCAL1,RGS6,CTH,BOC,SV2B,DTNB,FLT1,FYN,IGSF5,GDF9,KIRREL3,GRIK4,GRIK5,TMEM25,NKX2-2,IGSF11,PIK3C2A,PKD1,PTPRO,RGS7,KIRREL1,SLC1A2,SLC1A3,RPH3A,SLC1A7,TJP1,ZIC3,RGS7BP,IFT88" Drug 6971_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.15E-04 1.00E+00 1.20E-03 1.37E-02 49 185 "AMPH,APOC1,ARRB1,DNAH17,ATP2A2,KALRN,CRLF1,ENTPD4,PDE4DIP,FAM169A,TBC1D5,MED12,DRD1,TSPAN5,EFNA3,EPB41L1,RASGRP2,F5,FYN,HBS1L,MAP4,MAPT,CNOT4,PDE3B,PFKFB3,LRP12,KLK6,RAP1GAP,MYH14,ROM1,TCP11L1,SELL,SUPT20H,SLC1A7,SLC2A5,SLC22A4,LIMCH1,ZHX3,KDM4C,AJAP1,PLCB1,NPL,ZNF24,GDPD5,SCG2,SEMA3B,NAV2,EPM2A,ZNF248" Drug 2916_UP Letrozole [112809-51-5]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.15E-04 1.00E+00 1.20E-03 1.37E-02 49 185 "ADORA3,MTUS1,PLA2G6,AMPD3,BIN1,DDX3Y,BMP7,LDLRAD4,SULT4A1,RAB26,SIPA1L1,RIMS3,TMCC2,TRAPPC9,ABCC9,PHC2,CELSR3,ELN,STX2,KAT8,FGR,FLT1,ZNF44,GAD2,MSL3,GSN,VSIG4,IL6ST,AFF1,AFDN,ADAM22,ZNF862,P2RY1,SYTL2,MARCH1,RAB3A,RGS12,PBRM1,SEC14L1,SH3BP2,ANKRD6,ZHX3,DDN,MTCL1,SLC44A1,TMOD1,TRH,AMACR,ZBTB16" Drug CID000073211 AC1NUZ8M Stitch 1.16E-04 1.00E+00 1.21E-03 1.37E-02 29 92 "ALDH7A1,CFLAR,CACNA1I,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,CAPN3,AIFM1,CACNA2D2,CACNG7,CACNG3,CACNG2,GRM1,GUCY1A2,GUCY1B1,PTGDR2,NPR2,PDE2A,PKD1,MAPK3,RYR1,RYR3,TPCN2,TRH,VIPR2,SLC17A7" Drug CID000093117 conen Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 9 15 "ACTN1,ACTN2,CFL2,SEPT4,TNNT1,TPM1,TPM2,TPM3,TPM4" Drug CID000031657 Vydate Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 9 15 "ACHE,BCHE,DDR1,FOLH1,PTPN5,HP,HPR,PLEC,SHANK2" Drug CID000003423 FPL 64176 Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 9 15 "ADRB2,APC,CACNA1D,CACNA2D1,CACNB2,FOXM1,QDPR,RYR1,RYR3" Drug CID003035667 thiokynurenic acid Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 9 15 "GAD1,GAD2,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3" Drug CID000003068 AC1L1F3Q Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 10 18 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,ALDH7A1,INA,PDE3A,PDE3B,FXYD1,TAC1" Drug CID000130818 MNQX Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 10 18 "B3GAT1,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,GRM3,TACR1" Drug CID000108086 acromelic acid A Stitch 1.17E-04 1.00E+00 1.23E-03 1.39E-02 10 18 "GRIK1,GRIK3,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug 5271_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "NDRG2,AK2,APC,EPB41L5,PLA2G4C,ATM,CFLAR,SLIT2,RAB28,CLCN3,BAG4,EDRF1,RASSF2,DBT,HP1BP3,EXOG,MBNL2,SORBS3,ING4,FER,FGFR1,ZNF44,GLS,GPER1,PCLO,BRINP3,INPP5B,KITLG,NDUFA5,PCDH9,SLC25A23,MBOAT7,PRKAR1B,RAB3A,NEK11,FOXRED2,DOCK10,SLC9A5,SNCA,POGZ,PLCB1,TBCEL,TCF7L2,PSD3,NPL,ZMYND8,KCNK12,ZNF45,EPM2A,PHTF2" Drug 4114_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "PLA2G6,LTBP4,AMPD3,CDC42BPA,PKP4,APC,BCL7A,BMP7,CDC27,SOCS6,TAOK2,QKI,MICAL2,FAM169A,TBC1D5,GIT2,DTNA,FCF1,EIF4G1,EN2,ZNF589,FGFR1,GLYR1,RAB30,MSL3,IL6ST,JAK2,MAPT,MMP16,NEK1,NUMA1,SAMD9,LRRC49,PLEKHB2,ZCWPW1,TCP11L1,SH3BP2,PPP4R3A,FAM214B,PALLD,SON,PRRC2C,CAMSAP2,TBL1X,EHBP1,TCF7L2,TMPO,KAT6B,RBFOX2,WNK1" Drug 1835_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "ABHD6,NDRG2,ADD3,APBB2,APP,ARNTL,MARK4,CAPRIN2,ALDH4A1,ST3GAL5,SCAPER,MAP7,FEZ1,RIMS3,DNAJC6,GSDME,EFNA3,EPB41L2,EPS8,EXTL2,EYA1,TESK2,FGFR1,GABRA4,ADAM28,GPR19,PADI2,ITGA7,KIF5C,MAP4,SCAMP5,NCAM1,NEK1,NRGN,SERPINI1,PTCH1,WLS,SATB1,ITSN1,ANKRD6,PALLD,TSPYL2,RGL1,STXBP1,CAMSAP2,ATP13A2,TPM1,DNAJC12,CLIP2,ST7" Drug 410_UP 2-propylpentanoic acid; Up 200; 10000uM; HL60; HG-U133A Broad Institute CMAP Up 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "FAM131A,MARK4,ATP6V0A1,SYNJ1,SCAPER,WASF1,CLCN3,TMEM184B,RUBCN,KIAA0513,SPATA2,C2CD2L,SIDT2,EFNA3,EFNB3,MRNIP,BSCL2,ENO2,FGFR1,PCYOX1,FYN,RAB40B,GOLGB1,GRIK5,KIF5C,NRGN,SERPINI1,CCSER2,GPSM2,MAPK9,RAB3A,RPS6KA2,ITSN1,ELMO2,ZCCHC24,KIF21B,ZSWIM8,KIF1B,TSPYL2,STX1A,STXBP1,ATP13A2,SEZ6L,PLPPR2,CLIP2,KLC2,REEP1,LMAN2L,FIP1L1,MPPE1" Drug 4493_DN Securinine [5610-40-2]; Down 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "SHROOM2,IL33,BTRC,KYAT1,SCARB1,B4GALT6,LHX2,ZFYVE9,CLCN4,NMT2,TENM4,SLITRK5,SNPH,EGFR,ING4,MRNIP,STX2,ETV1,EZH1,ZNF589,SEMA4D,SYT17,SEPT9,POLL,GPD2,GUCY1B1,LSS,MX1,NDP,PAX6,MAPK8,PTCH1,PTPRE,PTX3,MCMBP,IL17RB,ASAP3,ZNF365,TNIK,SPATA7,EMC1,TCF4,KIAA0930,TRIM2,TNS2,TMEM121,TNS1,METTL3,ZBTB14,TRIM9" Drug 7305_DN Econazole nitrate [24169-02-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.18E-04 1.00E+00 1.23E-03 1.39E-02 50 190 "C1QTNF1,APP,SHROOM2,CASK,ADAM15,CFLAR,ARHGEF1,RAB28,NRXN3,ZFYVE9,QKI,NCOR2,DZIP3,USP6NL,ARHGAP32,GIT2,LYPD1,EFNA3,SORBS3,TAOK3,ANKFY1,NOP56,PDLIM5,FYN,GLYR1,MSL3,GPM6B,AGFG1,KIF2A,ARHGAP12,MEIS1,MSRA,NF1,NUMA1,FSD1,GON4L,SH3TC2,FAM102A,PPP1R9A,PEX26,KBTBD4,ZKSCAN3,ZNF415,CEP68,ARHGEF12,TMPO,TNS1,RUNDC3B,XRCC4,SF1" Drug ctd:D008140 Lorazepam CTD 1.18E-04 1.00E+00 1.23E-03 1.40E-02 5 5 "GABRA1,GABRA2,GABRA3,GABRA4,GABRG2" Drug CID000071001 3-hydroxy-2-quinoxalinecarboxylic acid Stitch 1.18E-04 1.00E+00 1.23E-03 1.40E-02 5 5 "GRIK1,GRIK3,GRIK4,GRIK5,ENOX1" Drug DB00659 Acamprosate Drug Bank 1.18E-04 1.00E+00 1.23E-03 1.40E-02 5 5 "GRIN3A,GRM1,GRM2,GRM3,GRM5" Drug CID000167842 bromowillardiine Stitch 1.18E-04 1.00E+00 1.23E-03 1.40E-02 5 5 "GRIK1,GRIK3,GRIK4,GRIK5,SOX10" Drug ctd:D008627 Mercuric Chloride CTD 1.19E-04 1.00E+00 1.23E-03 1.40E-02 229 1163 "ABAT,ACADM,ACHE,ACTN2,SLC25A25,NDRG3,ADD1,GRAMD1B,ADORA1,AGT,AK2,ALAD,FAM135A,PARG,APP,AQP4,ARHGDIA,ARHGDIG,ASPA,ASPH,PTCH2,ATP1A1,DOCK11,BCHE,C1QC,BTRC,CAST,CARS,KYAT1,CCNT1,USP2,CD86,ENTPD6,CDC42,CDH2,DCLK1,NOG,CHRM1,CHRNA4,CHRNB2,SLC22A6,CLU,TPP1,FADS2,ABCG2,HECTD1,TBPL1,COX4I1,CP,PNKD,CREM,RBM39,RGS6,ATRNL1,FAM169A,CTH,CTNND1,ZSCAN23,DCAF8,DGKG,DBT,SMG7,MTX3,ARNT2,DMD,USP3,CD99L2,NR1D2,SLC12A6,DPYSL2,ABI1,ABCC5,ABCC9,EDN1,HEYL,YAF2,EGFR,IRAK4,ING4,ELAVL3,USPL1,F3,FABP7,FCGR1A,FECH,FGFR3,SYNCRIP,NELFCD,ERGIC3,B3GAT1,GABRB3,ERAP1,MTHFD2,GATM,SESN1,MALT1,GJB1,GLDC,GNG3,GPT2,GOLGB1,RAPGEF1,NR3C1,KIF3A,ELOVL5,HMGB1,HMGCR,HP,IRF8,IGF1,IGFBP1,IL12A,LRRTM1,ITGAM,JAK1,JAK2,KCNH2,CLVS2,KCNK3,KLC1,IPO5,SFXN5,MAPT,MAT2A,AQP11,MEIS1,MOBP,MSR1,MT3,MTR,MYO5A,NACA,NEFM,NFIA,NFE2L2,NME4,NOS1,NPPA,SLC11A2,OGDH,P2RX7,PC,PFKFB3,CDK14,PGAM2,ABCB1,TMEM38A,PKM,PCDH18,STRN3,PSAT1,PRRX1,PPARA,MAPK3,MAPK4,MAPK8,MAPK9,PRPH,PTCH1,PTHLH,PTH1R,PXK,PTPRN,KLHL11,SLC25A36,ZNF532,ZC3H14,RPS20,RXRG,DGLUCY,AMER2,MAPK12,SARS,SCP2,CASC3,HSPA4L,SGK1,ANKRD6,SLC1A2,SLC1A3,SLC6A9,SLCO1A2,FAM219A,PDZD2,SPP1,ITPRID2,EPB41L3,LARP4,SS18,APOM,CEP68,STXBP1,ARC,TAC1,ALG1,EHBP1,DMXL2,ZEB1,SLC19A3,TF,DICER1,THBS4,THRA,TIMP4,HEY2,TP53BP1,TPD52L2,CDK20,AMACR,TRPM2,CA14,TST,RPRM,PITPNB,VSNL1,SLC47A2,AGMO,ZBTB16,MEIS3,PRTFDC1,LRP8,EVI5,SNX27,KCNAB1,FZD3,DOCK8,KAT6A,JMJD1C,NLRP3" Drug 2884_DN Clorsulon [60200-06-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "SLC12A5,CDC42BPA,ASPH,SLC4A4,SYNJ1,ARHGEF2,DNAJB5,CSF1,CNTNAP2,NOS1AP,MFAP3L,SMG7,RABGAP1L,EXOG,SLC12A6,EFNA3,SUGP2,SORBS3,VPS13B,EZH1,FGFR1,HBS1L,DISC1,GPD2,TDRKH,TJAP1,IL6ST,INPP1,VWA5A,MAP4,MDM4,SLC11A2,LRP12,MBOAT7,ZSCAN32,RAB3A,RAD52,ZNF821,EPN2,BTBD7,CXXC4,SNCA,RBM34,EMC1,ELOVL4,CRTC1,PCDHA6,TRIO,UBE3A,VIPR2,LMF1" Drug 2708_DN Hexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG2,SLC12A5,BIN1,CDC42BPA,PKP4,APOC1,PPP4R4,CDC27,CHM,CLCN4,AKAP7,NRG2,SUSD5,SMG7,EFNA3,EFNB3,ING4,TUBD1,RRAGB,F5,DLC1,FCGRT,KIAA1109,NBEA,PDLIM5,SRCAP,LILRA2,GRM7,MAP4,NNAT,NUMA1,CDK14,PLTP,STRN3,MED1,PRKCZ,SLC25A36,TCP11L1,SEC14L1,PREX2,SLC11A1,EMC1,TBL1X,TCF7L2,CRTC1,KAT6B,TPM3,SF1,TFIP11,WNK1,NLRP3" Drug 6067_DN Ricinine [524-40-3]; Down 200; 24.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG2,NME5,AK2,KCNAB2,MARK4,ALDH4A1,CADM3,NEURL1,ARHGEF2,PPP6R2,DAPK3,RUSC2,DTNA,EFNA3,MBNL2,IRAK4,ING4,C3orf18,FAM198B,PRELID3A,ALDH1L1,USP19,GNAS,GRB10,KCNF1,KCNJ3,KCNMA1,MAP4,MDM4,MID1,GIT1,PLXNB1,MAPK7,RAB3A,RAD52,RGS3,SBF1,SH3BP2,ZCCHC24,KDM4C,ARHGAP26,SS18,NCDN,STX1A,PLCB1,MCF2L,TRIM2,ZNF34,SLC44A1,PHTF2,SSPN" Drug 1628_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "MRTFA,KCNAB2,ARHGDIG,SLC4A4,ADAM23,CFLAR,CDK5R1,SYNJ2,GYG2,CACNG1,CAST,MAGI1,SH2B1,NCOR1,PDE4DIP,ARHGEF4,MBNL2,PLEKHA1,BAIAP2,FHL1,TXNL4A,HNMT,INPP5B,ITIH2,ADAM22,NUMA1,PLCD1,SLC25A23,RALGDS,CARF,CCDC25,ZC3H14,TCP11L1,RPS6KA2,ZNF821,TRA2B,KIF16B,TNIK,KDM4C,KIAA1107,PSD3,AHCYL2,CHST8,TMOD1,VGF,VLDLR,WIPF1,SPHK2,MAP3K12,EMSY,MPPE1" Drug 4738_UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASIC1,ACTN2,ADORA1,SEMA6A,LTBP4,BEGAIN,SEMA7A,CDK13,AZGP1,CACNA1G,CACNG1,CD86,ZFYVE9,CNTNAP2,DCAF4,DCT,TMCC2,DTNA,ECM2,EDN1,EDNRA,AASS,MTSS1L,CEND1,ZNF589,FHL1,GAD1,C1QL1,GRIN1,GRM7,IFI16,KCNH2,KHK,VWA5A,MAPT,MEF2C,NTRK2,PLCD1,TNPO2,POU6F1,C1orf54,PNMA8A,RPS6KA2,ASIC4,ATP10B,EPB41L3,SYT5,SEMA4A,CRTC1,SLC17A7,ITM2C" Drug 6176_UP chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASPHD1,BIN1,SEMA7A,CNTNAP1,APBB2,EPB41L5,BAIAP3,CACNA2D1,ASIC3,CHN1,CABP1,ARHGEF10,CNTNAP2,ARHGAP24,TMCC2,ATN1,SNX29,MRNIP,RASGRP2,KCNMB2,STX2,ANKMY1,OLFM1,FGFR1,FLNC,GPR153,GFRA1,GNAL,GRM8,PTGDR2,HSD17B1,KCNJ5,KPNA5,NF1,NNAT,PDE4D,CEP41,TMEM231,SEMA6D,SH3BGR,NTNG1,SLC1A7,PEX26,PALLD,SEPT8,PHLDB1,TAL1,DNAH7,SEZ6L,ZBTB16,STMN4" Drug 2544_UP Medrysone [2668-66-8]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "C1QTNF1,AMH,AZGP1,KSR1,CACNA1G,BAIAP3,CACNG1,CRLF1,NRXN2,DNAJB5,BRINP1,HS3ST2,TRAPPC9,DYRK1A,SEZ6L2,EDN3,AASS,EPHB1,EFS,FABP7,CAMSAP1,SCARA3,GABRA2,SIGLEC8,GLI2,TOX3,GPR37,GRIK1,GRIN1,SCIN,KCNJ5,TAGLN3,NCAM1,NUMA1,PDE4D,PPP1R1A,KHDRBS2,RGS4,SUGCT,PNMA8A,NEK11,SLC11A1,PALLD,SOX15,THRA,PRMT8,TRH,TUBB1,VAV2,ZIC3,SSPN" Drug 2364_UP Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG3,OSBPL1A,CDK13,CFLAR,BMP7,MTMR3,CA12,INA,CD38,ARHGAP33,CLCN4,CSF1,ARHGEF10,VCAN,ZFYVE16,DAPK3,KIAA0753,ABI2,PLXNC1,ELAVL3,COQ7,ZNF589,FHL1,CAP2,CELF1,GABRA2,GABRG2,MSL3,GNAO1,GRB10,SLC2A6,KHK,NNAT,NPR2,RGS3,HSPA4L,SLC1A3,ZKSCAN3,SNCA,KDM4C,ZC4H2,SEPT8,CEP68,ACSBG1,TAL1,PDLIM2,RPGRIP1L,DNAH7,TJP1,UBE3A,LMF1" Drug 6769_UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "LTBP4,KCNAB2,PDXK,DNAH17,RASL11B,ATM,CA4,ARHGEF1,DNAJB5,NECTIN3,RIMS3,DAPK3,ZNF804A,SGSM2,DMPK,FHL1,SCARA3,PDLIM5,USP19,COPS8,TDRKH,ICA1,ITPKB,ADAM22,TAGLN3,ZNF862,NF1,NLE1,PLCB2,PLXNB1,MBOAT7,PPARA,PTHLH,ZSCAN2,RGS12,SBF1,RPH3A,ARFGAP1,WDTC1,ZSWIM8,SPTB,IQSEC2,RBM26,PLCB1,PSD3,GPR161,ZNF34,VAV2,KCNK12,EPM2A,SSPN" Drug 5440_UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ADORA1,BIN1,APAF1,ATP1A3,CD86,SYNGR3,TPP1,SULT4A1,DMPK,DNAH9,TOM1,ST8SIA3,EYA1,OLFM1,FHL1,AFF2,PRELID3A,GABRA2,GABRA5,GATM,LPAR4,ICA1,KCNC1,KCNMA1,MAP4,MYO7A,NPR2,TMOD2,PLTP,MTRF1L,PDZRN4,SPATA6,POU3F4,LRRN3,KCNIP1,SALL1,SLC1A3,FAM214B,SLC11A1,OGDHL,ZCCHC24,NMNAT2,ACSBG1,POPDC3,WSCD1,TRIM2,R3HDM1,SEZ6L,TRIO,CLIP2,ZIC3" Drug 5265_UP Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "DPF1,MARK4,ATM,CFLAR,SYNJ2,CA8,CLCN4,FADS2,CRY2,NCOR2,SDC3,RIMS2,SRGAP3,DMPK,ATN1,EFNB3,EGR3,MTSS1L,KIAA1109,FGFR1,FOXG1,NSG1,GAD2,POLL,IL6ST,KCNB1,KCNH2,LSS,MAP4,AFDN,NF1,NPR2,NRGN,CLDN11,PLTP,CEP41,RIPOR1,ENOX1,RGS12,SEMA6D,ZNF821,SLC2A5,PKNOX2,BEX1,SYT5,EXOC7,DMXL2,KCTD2,SEZ6L,FLRT2,PARP11" Drug 5608_UP Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "C1QTNF1,ADGRF5,SEMA6A,LTBP4,ANK1,BCAS1,ADGRB1,ARHGEF1,NEURL1,LHX2,PICK1,WHRN,IFFO1,CSF1,IPCEF1,PHF14,RIMS3,DCT,EGR3,C3orf18,FHL1,HPCAL4,ADAM28,GNAO1,GRIK1,SPACA9,GRIK5,PTGDR2,ATXN2L,JAK2,VWA5A,MAN2A2,KITLG,MX1,NOVA2,MTRF1L,CEP41,MAPK7,RET,RGS12,TCP11L1,SEMA6D,SCN8A,SLC1A2,NCDN,POPDC3,TAL1,HEY2,PDIA2,VAV2,DNALI1" Drug 5330_UP Rolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "SERPINA3,C1QTNF3,ANK3,APC,EPB41L5,ASPH,ADGRB2,LDLRAD4,SOCS6,RAB26,JAKMIP2,ARNT2,DRD1,DSCAM,SORBS3,CDKL3,KIAA1109,FGFR1,C1orf61,PRELID3A,SRCAP,GRM8,NF1,NNAT,PCBP3,CCSER2,PLEC,PRODH,LRRC49,TMEM104,PTHLH,PTN,RGS10,ZNF821,ITSN1,FRMPD1,FNDC3A,SMTN,ZKSCAN3,MAPKBP1,KDM4B,TSNAXIP1,ZBTB43,PLCB1,PCDHGA10,ZNF34,PARD3,ZIC3,GDPD5,HPS4,NAV2" Drug 2868_UP Phenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "SYN3,ARID1A,AP2A2,PLA2G6,AMPD3,BIN1,PROM1,CACNA1I,CA4,CALB2,CAMK2B,ARHGAP33,NRXN1,CRMP1,KLHL3,DYRK1A,EDNRB,EFNA2,SORBS3,C3orf18,HSD17B14,ERCC2,ZNF391,FAM198B,PDLIM5,DISC1,GLS,GRIK5,TJAP1,KCNB1,ADAM22,BCO1,NPTX1,PENK,TMOD2,SERPINE2,PLTP,SELL,SH3BP2,SLC8A1,MAPK8IP3,ATP11A,SMG6,PCDHGB6,OBSL1,CRTC1,SLC44A1,TNS1,PRDM10,KCNAB1,CAMK1G" Drug 3474_DN Methazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "KIDINS220,APBB2,CDC14B,BTRC,CRLF1,SOCS6,TPP1,HOMER3,COL9A2,CRY2,FAM169A,DNAJC6,DNM1,DNM2,DSCAM,TOM1,MAMLD1,EPB41L1,KIAA1109,SEMA4D,TRAF3IP2,DISC1,INPP5K,IGSF1,IPO5,PAXBP1,LYRM9,PRPH,TMEM104,ELOVL2,ZSCAN32,RALGDS,RGS10,SBF1,BTBD7,ZKSCAN3,MAPKBP1,CAMTA2,ELOVL4,TTBK2,PLCB1,ATP11A,SEMA4A,EXOC7,AHCYL2,TPM1,CDK20,WBP2,UBTF,KCNK12,SMIM8" Drug 4110_UP Carbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ANK1,CACNA1I,BAIAP3,CALB1,CAMK2B,CDH2,CDO1,NRXN1,CNN3,PDE4DIP,RIMS2,DCAF4,TBC1D5,DGKG,ATN1,EFNA3,TENM1,FABP7,GAB1,GABRA5,STMN2,GRM7,GPR45,PTGDR2,ATXN2L,ITGA7,KCNN1,LMO1,VWA5A,MBP,MMP17,MX1,MYCN,NINJ2,NTRK3,CLDN11,PAX6,PLCD1,PPP5C,PTPRH,NUDT11,TMEM206,DOCK10,SLC1A7,SLC8A1,LIMCH1,KIAA1107,SYNE1,DOCK9,TRPC1,FLRT1" Drug 3001_UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ABHD6,ADORA3,NR0B1,C1QTNF1,APC,CDC14B,ASCL1,CAMK2B,HIP1R,CDH10,LGI1,PLEKHB1,CLCN4,AKAP5,NCOR2,RIPOR2,KIAA0513,DAPK3,MFAP3L,DMTN,FGR,DCTN2,GAA,POLL,PCSK1N,GPD2,GRIN2C,ADAMTS6,HRH3,IGF1,KCNN3,MMP16,MYO7A,P2RY13,NPY,NPPA,NTRK3,PDE1C,RAB3IL1,BEND5,GAL3ST4,RYR3,SEMA6D,ASAP3,PREX2,SYT1,HIF3A,TF,TMOD1,SSBP2,ZBTB16" Drug 3816_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "SLC12A5,BCAS1,PRX,ARHGDIG,CACNA1A,HAP1,USP2,DCLK1,CDO1,B4GALT6,CHRNB2,AKAP6,CSF1,CSF1R,RIPOR2,DLG4,DTNA,MBNL2,PNMA2,SIGLEC8,HSD17B1,HTR5A,ICA1,KCNJ5,KCNMA1,LAMA2,MATK,KITLG,MOBP,NF1,NOVA1,NPTX1,NPTX2,PRRX1,SPATA6,MAPK8,ZSCAN32,PNMA8A,EMID1,SLC8A2,NPAS3,INKA2,MAPK8IP3,DOCK9,TLR4,CADM1,OSBP2,SLC30A4,PRDM10,KCNAB1,PHTF2" Drug 7404_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ABR,PPFIA3,ADAM15,CAMK2G,CBFA2T2,TAOK2,SMARCAL1,SIPA1L1,SOCS5,DCAF8,DLG3,DTNA,SUGP2,EPB41L2,CINP,GPR153,OGA,TRAF3IP2,AHDC1,ZNF276,GLYR1,PADI2,ATXN2L,MAP4,MITF,NF1,NFYA,CNOT4,PC,SLC25A23,PMP22,LRRC49,CEP97,ZCWPW1,BSDC1,FOXRED2,ATXN2,SGK1,SH3BGR,FERMT1,AMBRA1,ABLIM3,CDK5RAP2,RCOR3,KDM4C,ELOVL4,CEP68,PHLDB1,ZNF106,KAT6B,RNF170" Drug 5813_UP Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASPHD1,ARID1A,C1QTNF1,MRTFA,CDC14B,KIF1A,CFLAR,CACNA1A,TAOK2,IQCK,ENTPD4,ST8SIA3,EDN1,IRAK4,EPHA5,STX2,FGFR1,BAIAP2,C1orf61,PRELID3A,PNMA2,ZMYND11,ALDH1L1,GPM6A,GRM8,JAK2,KCNJ5,MYT1,PIK3R1,TNPO2,POU3F2,SNRK,PID1,EMID1,ASAP3,SLC14A1,TMCC1,KDM4C,INKA2,KAZN,TAL1,TCF4,TRIM2,PIK3R5,NPL,VAV2,ZNF711,TFIP11,SEMA3B,PHTF2,DPF3" Drug 2975_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "MTUS1,CFLAR,FUBP1,CFAP410,SCARB1,ARHGAP33,CHRNB2,TAOK2,CLCN4,SLC4A7,CREM,CSNK1E,ZNF337,DCTN1,SMG7,E2F5,RASGRP2,PTK2B,OLFM1,CAMSAP1,PRELID3A,GAB1,GAD2,SIGLEC8,GNG3,PADI2,ATXN2L,KHK,AFDN,ADAM22,MSR1,CNOT4,OXTR,PPP5C,CEP41,TMEM104,PTPRN2,TMEM206,SEMA6D,GALNT10,ST6GAL1,SNCA,KANK1,CAMSAP2,PDLIM2,ADGRL3,PARD3,RBFOX2,FLRT2,BEST1,ZNF142" Drug 6738_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "DPF1,APC,ARRB1,ASCL1,ADGRB2,SCAPER,IL33,CFAP410,CA4,CACNA1D,HAP1,ARHGAP33,RGS6,SPOCK3,DRD1,EDIL3,HIPK3,TENM1,ING4,PLEKHO1,ETV1,FGFR1,C1orf61,ERGIC3,NSG1,RUNDC3A,TOX3,PRUNE2,GRIK3,ELOVL5,PACRG,ADAM11,KITLG,ADAM22,NF1,PFKFB2,PPP1R1A,PPP5C,MAPK8,ZMAT4,TMEM206,ZFP30,SLC2A5,ZNF334,ATP10B,ARC,EXOC7,SZT2,DOCK9,GPR161,CAMK1G" Drug 5427_DN Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG3,NME5,AK2,ALCAM,APC,MARK4,ASPH,SCAPER,CACNB2,KYAT1,CBFA2T2,QKI,ARHGEF6,CRY2,RUSC2,DTNA,FHL1,POLL,GNAS,GPER1,GRIK5,ATXN2L,MATK,ADAM22,NF1,NTRK2,NUMA1,SERPINI1,NLE1,PLXNB1,LRP12,PTHLH,ELOVL2,RAD52,ROM1,WLS,SYBU,COA1,TSNAXIP1,ERC1,PLCB1,ASTN2,PARD3,VIPR2,KCNK12,ZFP37,ZBTB14,SPHK2,GDPD5,PHTF2,SENP7" Drug 2733_UP Methazolamide [554-57-4]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ADRA1D,BBOX1,TRMT9B,ANK3,ASCL1,ASPH,PTCH2,ALDH7A1,AZGP1,KSR1,CDH8,CHI3L2,COL9A3,HAPLN1,MICAL2,ST8SIA3,SEZ6L2,HEYL,EGFR,CORO2B,ZNF44,SIGLEC8,SEPT9,MSTN,GRK4,GRM8,KCND3,MAG,MGAT3,MID1,AFDN,NOVA2,NTRK3,PCSK5,PTPRB,SUGCT,NEK11,SCN2A,SCN2B,NLGN1,SPART,SYT1,TAL1,TIAM1,SEZ6L,TRIO,VIPR2,LMF1,ZNF711,FAM13C,TIGD6" Drug 4345_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "RALGAPA1,ACTN2,ADRA1D,LTBP4,MRTFA,MARK4,CADM3,SGCE,CAMK2B,CDH18,MAGI1,CRLF1,QKI,CPS1,GIT2,RABGAP1L,SLC12A6,EDNRA,EFNA3,EFNB3,TNK2,LRRC23,IGSF6,PTK2B,OGA,HBS1L,SRCAP,RND1,GNAS,GPR37,GRIK5,NR3C1,IL6R,ITIH2,OCRL,RETREG1,STRN3,RGS12,MYH14,CLSTN2,JMJD6,ROBO3,EXOC7,PSD3,CRTC1,TMEM121,CHST8,HEY2,TRPC1,ZKSCAN5,NUP214" Drug 3327_UP Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ARID1A,ALCAM,APAF1,APBA2,FAM131A,CACNA1I,LDLRAD4,CACNB2,CACNG1,HAP1,CHRNB2,TAOK2,ARHGAP24,AK5,EDNRA,HIPK3,EGR3,VPS13B,ZNF589,FGFR1,OGA,RUNDC3A,RND1,GNAS,ADAMTS13,GRIK5,KLF12,ICA1,C2orf72,JAK2,KCNN1,MMP17,MSR1,OMG,TREM2,LRP12,PPP2R2B,SAMD9,ZNF493,TRIM68,RET,MYH14,CARF,RASA3,SLC1A2,KDM4B,WDTC1,DMXL2,ZFP37,MKRN3,MVB12B" Drug 3715_DN Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASIC1,APOC1,CDK13,NRXN3,HAPLN1,NCOR2,CNIH3,AK5,SGSM2,EDN1,SGK2,SIDT2,OPTN,ING4,MRNIP,LRRC23,FGFR1,C1orf61,TRAF3IP2,KCNMB4,GPM6A,ATXN2L,ELOVL5,VWA5A,GIT1,NELL2,NPR2,PDE4B,PIK3R1,MAPK7,MAPK8,WDR25,PTCH1,PID1,ROM1,TCP11L1,SLC9A5,LIMCH1,SNCA,KDM4B,TSNAXIP1,MLC1,ATP11A,TBCEL,MGRN1,TEX15,TIAM1,TNS1,RPRM,VAV2,VIPR2" Drug 7099_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "LTBP4,ARNTL,CDK13,MARCH3,BMP7,ST3GAL5,GYG2,NECTIN3,DAPK3,DTNA,E2F5,SEZ6L2,RASGRP1,SIDT2,MBNL2,EGR3,SORBS3,RGS17,VPS26C,ZNF589,ZMYND11,SYT17,CRCP,MSL3,TDRKH,ICA1,KCNF1,KIF5C,MKLN1,LYRM9,PFKFB3,CCSER2,RETREG1,PTPRE,RALGDS,RPS6KA2,SBF1,ZNF821,AMBRA1,STX1A,ANKRD12,SEMA4A,EXOC7,KIAA0930,PCDHA6,TIAM1,PARD3,CABIN1,TPM1,GDPD5,NAV2" Drug 2875_DN Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG2,MTUS1,AMPD3,KCNAB2,BCAS1,APP,ATM,SLC4A4,CFLAR,KRIT1,ARHGEF1,RCBTB2,CHM,RAB28,ZFYVE9,CLU,USP6NL,DTNA,HIPK3,EFNA3,ING4,DMTN,F3,FGFR1,FHL1,PDLIM5,RAB30,HSF2,IL6ST,INPP5B,MAP4,MPP2,STRN3,PPP5C,MAPK8,PLPPR1,SLC25A36,SEC14L1,ZNF365,RBM34,WDTC1,SOX3,PLCB1,IQCE,TNS2,AHCYL2,TMOD1,KAT6B,UBE3A,PLPPR2,DNALI1" Drug 3826_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ADGRF5,SLC4A4,BMP7,LARGE1,HOMER3,PICK1,AKAP5,ABI3BP,IFFO1,SH2B1,DCAF4,DAPK3,MFAP3L,DUSP9,CELSR3,SUGP2,KIAA1109,CINP,PRELID3A,GPR75,GPM6B,GPR17,GRIK5,CACFD1,HAS2,ATXN2L,ITGA7,ITIH2,KCNMA1,KIFC3,TM6SF1,MDM4,NTRK2,RETREG1,PTHLH,RGS4,RXRA,RASA3,DOCK10,NLGN1,FAM214B,ZNF334,RBM34,WDTC1,DOK5,LHPP,COLGALT2,ARC,GPR161,TK2,PARP11" Drug 5460_DN Acemetacin [53164-05-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ABR,ADCY6,NME5,APBB2,PPFIA3,CDC14B,ARHGDIG,BRINP2,KIF1A,CBFA2T2,CLGN,ABI3BP,CSNK1E,SIPA1L1,CNTNAP2,DOCK4,RUSC2,MED12,TRAPPC9,DTNA,PLXNC1,LRRC23,KAT8,FHL1,ANKFY1,GPM6B,GRIK5,IL6ST,MAP4,ADAM22,NDUFA5,NUCB1,NUMA1,SERPINE2,MAPK7,ELOVL2,RIPOR1,ZDHHC14,ASAP3,SLC6A8,MAPKBP1,INKA2,TTBK2,PLCB1,PCDHA6,AHCYL2,SLC44A1,PARD3,TRPC1,MPPE1,SENP7" Drug 7449_UP Risperidone [106266-06-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "AP2A2,BEGAIN,BIN1,CDC42BPA,NRP2,GYG2,ARHGEF10,CNTNAP2,SDC3,RIMS2,NOS1AP,EIF4G2,ZNF589,FGFR1,EFCAB2,GPR153,FYN,GAD2,GAP43,SIGLEC8,RAB30,GNAS,TDRKH,GRM1,RNFT2,KCNJ5,MAP4,MEF2C,MIA2,AFF1,MMP16,LYRM9,MYH6,NNAT,OPCML,PRKCB,MAPK12,SH3BP2,SLA,SLC2A5,SPTAN1,INKA2,ELOVL4,ROBO3,SMG6,PCDHA5,TNS1,FAM155A,VSNL1,KCNK12,PRDM2" Drug 5990_UP Thalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "DPF1,ADORA2A,LTBP4,AMH,BIN1,SEMA7A,APAF1,KCNAB2,MTMR3,CA12,CACNG1,MTMR7,CDC42,CDH18,DNAJB5,CNTFR,ING4,VPS13B,RASGRP2,MTSS1L,ERBB4,DLC1,HPCAL4,FOXG1,OGA,GAB1,SIGLEC8,GLI2,POLL,GRM8,TJAP1,KCNN1,KIT,MYT1,NPPA,NTRK3,MAPK7,PTAFR,SBF1,FAM214B,KANSL3,SORCS3,WDTC1,UHRF1BP1L,NPAS3,WSCD1,TCF4,DOCK9,FAM155A,MICAL1,ADAMTS9" Drug 843_UP 5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "AK2,KCNAB2,SLC2A11,CFLAR,SCARB1,PLAA,RCHY1,CREM,CTH,RIMS2,USP6NL,GIT2,CELSR3,ENO2,F8,FGFR1,FHL1,DPYSL4,FAM49B,SYT17,DIDO1,INPP5B,KIF2A,LIG4,LYRM9,MAPK8,PSMD13,ZSCAN2,ROM1,EMID1,FAM214B,SLC11A1,SLC20A2,ZKSCAN3,SMARCD3,ZCCHC24,ZBTB43,DIP2A,STX1A,PLCB1,DNMBP,KIAA1107,SMG6,PCDHA5,AHCYL2,GPR161,RBFOX2,ZMYND8,MAP3K12,NT5M,EVI5" Drug 5399_DN Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "RALGAPA1,NME5,APLP1,BRINP2,CFLAR,UBE2L6,ADGRG1,FOXN3,CHM,TAOK2,SLIT2,RCHY1,SH2B1,CTNND2,PPP6R2,ZNF804A,DNM2,DTNA,SIDT2,EFNA3,SORBS3,IGSF6,ZNF589,DISC1,GCNT2,GLYR1,GSN,INPP1,NF1,NUCB1,ELOVL2,FAM120C,PEX5,RAD52,SBF1,AMBRA1,SLC1A7,SPTAN1,FCHO1,PLCB1,KAZN,FBXW11,TNS2,CRTC1,PCDHA6,TGFBR3,SLC44A1,TK2,CABIN1,ZKSCAN5,VGF" Drug 3366_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "SYN3,ADRA1B,ALCAM,PDE8B,CFAP410,HIP1R,NEURL1,ARHGEF2,CDH8,CHRNB2,SNCAIP,VCAN,DAPK3,ARMCX2,DCT,DYRK1A,ERCC2,REEP2,PTK2B,KIAA1109,FOXG1,GAP43,SIGLEC8,GCNT2,HPGDS,GRIK5,GSN,KLF12,MDM4,MYT1,NNAT,NPR2,OMG,PDE4B,TMOD2,POU3F2,MAPK8,PLPPR1,RAB3IL1,RPS6KA2,FOXRED2,KDM4B,WDTC1,SOX10,HECW1,LMO3,PHLDB1,HIF3A,LILRA4,TRPM2,NUP214" Drug 2472_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "BIN1,APAF1,BCL7A,HIP1R,FOXN3,PLAA,STOML1,ABCG1,G3BP2,DTNA,EPS8,PIPOX,ST3GAL6,KIAA1109,IQCG,EFCAB2,POMT1,OGA,FYB1,GABRA2,ZMYND11,SEPT9,POLL,EML4,ATXN2L,TJAP1,KIF2A,MAP4,NCAM1,NFYA,ST8SIA5,PLCD1,PTAFR,PTN,RIPOR1,ZCWPW1,MRAS,SLC11A1,SLC20A2,SNCA,EMC1,TROVE2,SEPT8,ARHGEF9,CAMSAP2,ADGRL3,KIAA1107,XRCC4,ZNF24,MAP3K12,TIGD6" Drug 4467_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ACTN2,BEGAIN,APAF1,BCHE,NRP2,CFLAR,KSR1,IL33,CA12,ABCG2,HOMER3,DGKG,SPOCK2,GIT2,CHRDL1,CDON,TNK2,ST3GAL6,TESK2,KIAA1109,FGR,C1orf61,SIGLEC8,PCDH17,GLYR1,MSL3,GPR19,STON1,GPER1,CACFD1,NXPH3,LAMA2,ADAM22,CEP41,PKN2,PTN,PTPRN2,SH3TC2,ARID4A,PNMA8A,KCNIP1,ATXN1,ARHGEF40,SLC11A1,HECW1,ATP10B,ADGRL3,TEX15,TPM2,ZNF225,KCNAB1" Drug 419_UP chlorpromazine hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "NDRG2,AMPD3,BIN1,APC,APOC1,DNAH17,CANX,CDH18,CHRM4,AATK,ARHGEF4,KIAA0586,TRAPPC9,DYNC1I1,DRP2,SIDT2,EFNB3,SUGP2,MBNL2,TNK2,EPHB1,HPCAL4,CYP46A1,RUNDC3A,SOX21,SLC2A6,ITPKB,MAP4,TM6SF1,MMP17,MX1,NPPA,PLEC,SMOX,ZNF821,SH3BP2,FNDC3A,SLC6A8,EMC1,LMO3,PHLDB1,ANKRD12,EXOC7,SEZ6L,CLIP2,WNT7A,ZBTB16,WNK1,SLC17A7,KCNAB1,MVB12B" Drug 4386_DN Rescinnamin [24815-24-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "APLP1,APP,CDK13,PDE8B,SLC4A4,CFLAR,MTMR2,CRLF1,FOXN3,TAOK2,AKAP7,RCHY1,SIPA1L1,PDE4DIP,SPOCK2,KBTBD11,DMPK,DSCAM,SORBS3,BAIAP2,C1orf61,EFCAB2,FAM49B,GAB1,MALT1,RUNDC3A,GNAS,GNG4,GSN,ATXN2L,MATK,KITLG,MOBP,NEUROD1,PPP5C,PTHLH,RAB3A,BSDC1,FNDC3A,COA1,PLCB1,ARC,PSD3,ARHGEF12,DICER1,ZNF384,FLRT2,LMF1,SEMA3B,ST7,KAT6A" Drug 5047_DN Chloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASIC1,ADRA1D,TRMT9B,BIN1,APC,LGR5,CDC14B,CDK10,BACH1,CDK5R1,HAPLN1,CSF1R,TOX,MBNL2,SORBS3,PLEKHA1,LRRC23,ZNF391,CDKL3,BAIAP2,TRAF3IP2,GAD1,SRCAP,ZNF276,KCNMB4,KLF12,KIF5C,MAPT,MBD1,MX1,ODF2,PLXNB1,FSD1,FAM120C,RPS6KA2,ATXN7,DZIP1,PPP4R3A,KANSL3,ZNF667,ZNF415,ADGRL3,TCF4,TK2,TRIO,OSBP2,LMF1,UPF3A,MAP3K12,SCG2,KAT6A" Drug 1984_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASIC1,ACLY,ACTN2,C1QTNF3,PPFIA3,ARHGEF7,BTRC,ZFYVE9,RAB26,CSF1R,OSBPL3,ZFYVE16,KIAA0586,SMG7,CNNM1,EZH1,TESK2,KIAA1109,EFCAB2,CELF1,FYB1,GART,SLC2A6,NXPH3,KLF12,HTR2A,TJAP1,LSS,MYT1,NINJ2,NRGN,PLCD1,FTO,PTPA,PPP3CB,RAB3IL1,ARID4A,FBXW7,TCP11L1,RPS6KA2,SH3BP2,AMBRA1,ZCCHC24,MAPK8IP3,STXBP1,WBP2,CA14,ZKSCAN5,HIRA,DNAJC12,HPS4" Drug 5245_DN Butylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "RBM10,DGKD,PLA2G4C,ATM,MTMR2,ZMYM4,SRSF11,SLIT2,QKI,CREM,ARHGEF4,ZNF804A,PARD6A,ATN1,CNNM1,TNK2,ANKMY1,MALT1,FERMT2,GPER1,NR3C1,HNMT,ITPKB,KCNH2,ZNF862,NAP1L1,NFYA,PCDH9,PMS2,PPP2R2B,PPP3CC,PRKAR1B,PTPRE,RAB3IL1,RIC8B,CLIP1,RXRA,SFPQ,FBXO11,ZNF302,ATP11A,EHBP1,TCF7,TCF7L2,AP4E1,CBX5,ZMYND8,ZKSCAN5,GDPD5,UBE3B,SENP7" Drug 2223_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "RALGAPA1,C1QTNF1,MRTFA,FAM131A,CFLAR,CACNA2D1,SLC16A4,EPS15L1,CLU,TCEAL2,CSF1,MAML1,SPOCK2,CNIH3,SPOCK3,RABGAP1L,DYRK1A,MBNL2,NCALD,FHL1,GAD1,ADAM28,RUNDC3A,MSL3,IL6ST,ITPKA,MAN2A2,MAP4,BCO1,PCBP3,OPRL1,LRP12,MAPK7,GDPD2,PNMA8A,BCAN,SLC11A1,OGDHL,ZSWIM8,ZNF423,ATP10B,PSD3,PCDHA5,TGFBR3,KAT6B,TRPC1,ZMYND8,VGF,WNK1,NT5M,NUP214" Drug 5444_UP (S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ACTN2,KIDINS220,AMPH,APOC1,PPP4R4,ASPH,ARHGEF7,CA4,SLC16A4,RCBTB2,FOXN3,SLIT2,WHRN,BAG4,CREM,DCAF4,MFAP3L,ECM2,ING4,IGSF6,FGFR1,GLS,GPR22,NR3C1,PTGDR2,C2orf72,KCNF1,MSI1,ADAM22,SLCO1C1,PDPK1,PLTP,CEP41,RELN,PTHLH,RAD52,RPS6KA2,RPH3A,RAB3GAP1,OGDHL,TNIK,ZNF423,IQSEC2,MTCL1,DOCK9,TK2,TNS1,TRIO,ZIC3,WNK1,NUP214" Drug 4192_DN Roxithromycin [80214-83-1]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "MTUS1,TRMT9B,APP,CDK13,BRINP2,ST3GAL5,C5,ARHGAP22,PLAA,DNAJB5,LY86,AATK,RGS6,ARHGEF4,CTNND2,DBT,EXOG,ETV1,RRAGB,F5,ANKFY1,OGA,KCNMB4,GNAS,GPM6B,GRM8,GUCY1B1,MUM1,INPP5B,PROX1,ZDHHC14,RGS4,MAPK12,CSRNP3,MRAS,FBXO11,BCAN,PPP4R3A,SOX2,DDN,SS18,VAMP1,DNAH7,THRA,TIAM1,SSBP2,VGF,WIPF1,XRCC4,KCNAB1,NUP214" Drug 3530_DN (-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ASPHD1,KIDINS220,BIN1,AMT,KCNAB2,RASL11B,ATM,CFLAR,NEURL1,SOCS6,SULT4A1,WHRN,ABI3BP,NECTIN3,CRY2,CSNK1E,CTIF,RUSC2,RCAN1,SUGP2,NCALD,GAB1,SPACA9,MAP4,MAPT,ADAM22,NF1,NNAT,SLC11A2,OPCML,MBOAT7,PPARA,PRODH,PEX5,RALGDS,EMID1,SEMA6D,SON,STX1A,VPS13A,ROBO3,PSD3,CHST8,ZNF34,SLC44A1,CABIN1,ZKSCAN5,VLDLR,SPHK2,ST7,KAT6A" Drug 5825_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ADD2,AP1B1,AK2,APLP1,PPFIA3,PDE8B,ATM,CFLAR,CLU,NRG2,NCOR1,SDC3,INTS1,SIRPA,LPAR6,COQ7,TESK2,FECH,CAMSAP1,FAM49B,AHDC1,GLS,IL6ST,INPP5B,MEF2C,MEIS1,PDE1C,PLCD1,FSD1,PTPA,MAPK7,RIPOR1,ARHGEF10L,RPS6KA2,PAQR6,SAFB,IL17RB,PEX26,BTBD7,ZKSCAN3,SMARCA4,COBL,EXOC7,CABIN1,NR2C2,TRIO,UBTF,PRDM2,GDPD5,VPS35L,ST7" Drug 3942_UP Acacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.20E-04 1.00E+00 1.23E-03 1.40E-02 51 195 "ABCD2,AMH,AMT,PDE8B,ATP2B2,N4BP2L1,ADAM23,RGS11,KSR1,CDH10,EPS15L1,RAB33A,CTIF,SPOCK3,TRAPPC9,ABCC9,TNK2,ELN,LRRC17,ERCC2,CDKL3,DLC1,OLFM1,FLNC,ALDH1L1,CSDC2,POLL,GRM3,AP4S1,GUCY1B1,HRH3,MDFI,MGAT3,CD200,ZNF862,NTRK2,PFKFB2,PTH1R,MYH14,FRMPD1,ST6GAL1,SLC2A5,SHANK2,JMJD6,TNS2,THRA,TRH,ADAMTS9,SLC17A6,TIGD6,AP3B2" Drug CID000133240 N-propanoylmannosamine Stitch 1.20E-04 1.00E+00 1.24E-03 1.41E-02 15 35 "ST3GAL5,NTM,ST8SIA3,ST3GAL6,ST6GALNAC3,CHL1,L1CAM,NCAM1,NCAM2,ST8SIA5,MAPK3,ST6GAL1,ST3GAL3,ST8SIA1,ST8SIA2" Drug CID000002083 salbutamol Stitch 1.20E-04 1.00E+00 1.24E-03 1.41E-02 41 147 "ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,ARRB1,ALDH7A1,ASIC3,CHRM1,CLTC,QKI,CSF1,PLEKHM1,NR1D2,DRD1,FCGR1A,FOXM1,GNAS,TNFAIP8L3,IGF1,IL12A,NEUROD1,PDE4A,PDE4B,PDE4D,PDGFRA,PKIA,PTPRN2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,ZNF365,SCN3B,ARHGEF12,TMEFF2,HPS4" Drug 3822_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "AMPD3,KCNAB2,MARK4,ATP1A3,CADM3,KSR1,BMP7,SCAPER,CBS,CNTNAP2,RIMS2,CYBB,DAPK3,MYEF2,MFAP3L,SPOCK3,EFNA3,EFNB3,EIF4G2,LRRC23,EPHA5,F5,DLC1,FGF1,SCARA3,SEMA4D,FYB1,GBX2,GPR75,SPACA9,LAMA2,ZNF862,PBX1,ZSCAN32,ZSCAN2,RAB3IL1,ZNF821,SLC1A7,SLC2A5,SNCA,DDN,THSD1,TCF7L2,TNS1,SEZ6L,CDK20,ZMYND8,HIRA,CADM1,VGF,NAV3,PARP11" Drug 2542_UP Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "C3orf14,ACTN2,ARID1A,APP,ALDH4A1,ATP6V0A1,NMT2,CPS1,ZNF337,KLHL3,DLG3,ATN1,CNNM1,COQ7,KIAA1109,FGF12,FHL1,GABRA4,GAD2,GALC,GLYR1,LILRA2,PCLO,KLF12,ITIH2,LSS,MAP4,PFKFB4,CCSER2,PLEC,PPP5C,PTAFR,PTPRN2,RIPOR1,BEND5,NEK11,SCG5,SH3BP2,PREX2,LIMS2,SLN,TMCC1,TNIK,SOX10,DOK5,MAPK8IP3,TBL1X,TCF7L2,TK2,SEZ6L,ZMYND8,XRCC4" Drug 1741_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; HL60; HG-U133A" Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "APBB2,APOC1,APP,CDK10,MARK4,ATP2A2,CADM3,CFLAR,BMP7,CACNA1A,CACNA1D,P2RX6,CD86,SOCS6,CHN2,ZFYVE9,CNTFR,CRYM,INTS1,DAPK1,C2CD2L,TMCC2,MRNIP,TMEM35A,GABRG2,NXPH3,MMP16,MN1,ADAM22,NCAM1,NTRK3,PLCB2,PTN,CCDC40,ZFHX4,FBXW7,TCP11L1,PAQR6,SH3BP2,ZBTB43,NCDN,CAMSAP2,PDLIM2,PHF24,ZMAT3,PARD3,CA14,TUB,WNK1,GDPD5,RNF170,DPF3" Drug 5513_UP Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ADRA1D,MRTFA,TRMT9B,GAS7,PDE8B,ALDH7A1,SCAPER,CACNA1I,RAB29,SPAG9,CLGN,MFAP3L,HP1BP3,RUSC2,KBTBD11,EPHB1,FHL1,FYB1,GABRA2,GABRA5,GPD1,ADAMTS13,GRM2,GRM8,BTN2A1,LIG4,SMAD1,MAP4,MSR1,NEFM,NF1,NNAT,MTRF1L,STRN3,PACSIN1,GRAMD1C,FAM120C,ZDHHC14,GTDC1,PAQR6,ITSN1,SMTN,OGDHL,STX1A,SYN2,TACR1,MCF2L,DOCK9,TRPM2,KCNK12,XRCC4,WNK1" Drug 5700_UP Felbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "RALGAPA1,PLA2G6,AQP4,ASCL1,MTMR3,C5,BAIAP3,CALB1,CALB2,CD38,CDH8,CRLF1,SLIT2,ZFYVE9,DNAJB5,OSBPL3,ARHGEF4,EGFR,EGR3,C3orf18,F5,GAD1,C1QL1,RUNDC3A,NR3C1,ICA1,JAK2,KCNJ4,MAOB,SHC3,MYCN,OGG1,ENPP2,STRN3,PTPRB,PTPRN2,RAD52,ATG16L1,KCTD17,TCP11L1,RASA3,SOX2,ZC3H13,JMJD6,TRIM2,DICER1,TK2,PIK3R5,CHST5,GDPD5,PAK5,GJC2" Drug 6477_UP Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "BEGAIN,ANK1,APOC1,ARHGDIG,ASTN1,CADM3,FGF17,CFLAR,KSR1,SYNJ1,SCAPER,CAMK2B,CDH2,TAOK2,HOMER3,AKAP7,ATRNL1,DMPK,ST8SIA3,ING4,OLFM1,FGFR1,PDLIM5,TMEM8B,SIGLEC8,GRIN1,HTR2A,SMAD1,NDUFA5,OPCML,PALM,LRP12,PRKAR1B,ZMAT4,RGS12,RTN1,PPP4R3A,FAM214B,LIMCH1,ARHGAP26,CLSTN2,AJAP1,POPDC3,TACR1,WSCD1,TRIM2,TLR4,FAM155A,SLC30A3,SLC17A7,ADAMTSL3,JPH3" Drug 1955_DN Haloperidol [52-86-8]; Down 200; 10.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ABHD6,BRAP,PLA2G6,APP,EIF4G3,ATP2B1,WASF1,CDC27,SRSF11,FOXN3,NIPBL,NECTIN3,PREPL,ENTPD4,CTH,TBC1D5,RCAN1,SORBS3,PLEKHA1,EFEMP1,NCKAP1,GART,GHR,CRCP,GLS,BTN2A1,GSTM5,KTN1,MX1,NAP1L2,NFE2L2,NFYA,PFKFB3,CDK14,CCSER2,TRHDE,PTPA,C1orf109,SH3BP2,FERMT1,FBXO11,PEX26,SMTN,PEG10,ZNF302,EPB41L3,MAPK8IP3,STAU1,SEPT8,TCF7L2,KLC2,EVI5" Drug 4379_DN CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ASIC1,DOC2A,AMPD3,CDC42BPA,CNTNAP1,APBB2,BRINP2,ATP2A2,BMP7,CACNA1I,SCARB1,CDH18,FOXN3,ARHGEF6,PICK1,AATK,DRD1,EFNB3,NCALD,PIPOX,PTK2B,DLC1,OLFM1,FGFR3,FHL1,SCARA3,KHDRBS3,DISC1,INPP5K,GPM6B,TJAP1,ITIH2,KCNN2,MSI1,NOS1,POU3F2,MAPK10,SAMD9,RAB3IL1,RGS10,SH3BP2,SMARCD3,SNCA,ARC,WSCD1,ARHGEF12,GPR161,THRA,DAAM2,PDIA2,PLPPR2,ZIC3" Drug 1722_UP Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ADCY2,C1QTNF3,AMT,EPB41L5,INA,P2RX6,SCARB1,CHGA,ZFYVE9,KIAA1549L,PICK1,SEC31B,RUBCN,C2CD2L,SMG7,DPP6,COQ7,RASGRP2,ANKMY1,OLFM1,FGFR1,AFF2,FAM107A,MUM1,MPP2,GIT1,MYL3,NINJ2,NTRK3,OCRL,RETREG1,RETREG2,MAPK3,MAPK10,DEF8,RGS3,RXRA,AMBRA1,SLC1A7,FAM214B,EMC1,UNC5B,ATP10B,PLCB1,THBS4,PARD3,RBFOX2,ZMYND8,PLPPR2,ZNF142,SLC17A7,ZNF248" Drug 4387_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ADRA1D,KIDINS220,BEGAIN,SLC4A4,SGCE,BAIAP3,CFAP410,HAP1,CACNA2D2,FAM149A,OSBPL3,IPCEF1,PHF14,RIPOR2,KLHL3,EDN1,EFNB3,LRRC17,ETV1,KIAA1109,EFCAB2,NSG1,TBR1,FYB1,GAD1,GPD2,STON1,GRIN1,KLF12,LMO1,VWA5A,LSS,NCAM1,GPR85,POLG,CEP41,CCDC40,SUGCT,SLC2A5,LIMS2,KANSL3,ZNF334,RIMS1,SNAP25,HECW1,ARHGAP26,CDK19,PHLDB1,TK2,AMACR,LAT2,ITM2C" Drug 4140_UP Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ASPHD1,AP2A2,SPARCL1,MRTFA,ATP1A2,ATP2B2,N4BP2L1,ADAM15,BCL7A,SYNJ2,CACNA1I,RUNX1T1,HOMER3,WHRN,CRY2,CST3,RIMS2,DAPK3,SPOCK2,NTM,DMPK,EFNB3,CEND1,OLFM1,GNAL,GPER1,ACOT7,ICA1,C2orf72,ITGA7,KCNJ3,KCNMA1,KCNN1,MAOB,OGG1,GDPD2,RAB3A,RAB3IL1,TRIM68,TTLL7,SH3BP2,SLC2A5,SLC11A1,SHANK2,LIMCH1,DOP1A,FAM168A,KIAA1107,CRTC1,TPM2,VAV2,SSPN" Drug 3020_UP Nadolol [42200-33-9]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ABAT,GRAMD1B,APP,ARHGDIG,ARRB1,ASCL1,ASPH,MYOM1,BMP7,SULT4A1,NCOR2,PDE4DIP,EGFR,FER,GAD1,GALC,ARPP21,GPM6B,LILRA2,GRIK5,GSN,GUCY1A2,PTGDR2,HNMT,LSAMP,SMAD1,MBNL1,MDFI,NEFM,OPCML,SEPT4,FSD1,RELN,PTHLH,RGS4,GALNT10,SLN,PALLD,TMCC1,CDK19,VAMP1,SYN2,SYT1,GPR161,TK2,TMOD1,TPM3,VAV2,KCNK12,SPHK2,ACTR3B,GAN" Drug 7456_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "FZD9,LTBP4,AMH,BIN1,APC,ARRB1,ALDH4A1,SCAPER,GYG2,INA,SEPT7,CRLF1,GPR37L1,FOXN3,SOCS6,ENTPD4,NCOR2,TBC1D5,MFAP3L,SLC12A6,RCAN1,MRNIP,AFF2,OGA,SYT17,CSDC2,GRIN2C,TJAP1,ITPKB,KCNN1,MATK,NOS1,SLC11A2,NTRK2,PALM,PDPK1,PLXNB1,PACSIN1,PPP2R2B,WDR25,RPS6KA2,SEMA6D,SBF1,SLC1A7,SLC6A9,TSNAXIP1,MAPK8IP3,VAMP1,TEK,VAV2,SLC26A10,SLC30A3" Drug 6408_UP valdecoxib; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "APC,CDC14B,BCL2L2,CDK5R1,CACNA1I,CFAP410,ARHGEF1,CNOT8,CRY2,CSF1,EDRF1,CTIF,B3GAT3,MFAP3L,CHRDL1,EDIL3,SORBS3,MRNIP,DLC1,FGFR1,BAIAP2,TRAF3IP2,DISC1,MSL3,PRRC2B,GPM6B,TDRKH,SHISAL1,KIFC3,MAN2A2,TM6SF1,ZNF862,NF1,NPR2,PLCD1,SAMD9,RGS3,MYH14,TCP11L1,SBF1,STUM,RASA3,FUZ,SLC4A3,SLC6A9,IFT122,MAPK8IP3,VPS13A,COBL,ASTN2,TK2,WNK1" Drug 6033_DN Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "RALGAPA1,ASIC1,ADRA1D,PLA2G6,FAM131A,CDC14B,ALDH4A1,ARHGEF7,CACNA1I,USP2,CBFA2T2,ARHGEF2,CHRNB2,TAOK2,RCHY1,CSF1,RASSF2,SLC12A6,TOM1,EN2,F3,ZNF589,FOXG1,IQCG,FYB1,GAB1,SYT17,SRCAP,GRM1,INPP1,KCNH2,KCNJ3,SMAD1,ZNF862,NUMA1,NLE1,SLC25A23,MBOAT7,RAD52,TCP11L1,RPS6KA2,ASAP3,BTBD7,ZCCHC24,IQSEC2,TSPYL2,THSD1,VPS13A,ATP11A,DICER1,TK2,KCNAB1" Drug 4075_DN Metrizamide [31112-62-6]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "RALGAPA1,CDC42BPA,GAS7,APOC1,PPP4R4,DNAH17,ASTN1,SYNJ1,DNAJB5,CNTFR,TCEAL2,TENM4,FAM169A,ARHGAP32,DAPK3,DBT,MFAP3L,DTNA,EDN1,FCF1,SIDT2,FAM13A,PLXNC1,IRAK4,ZNF549,FGF1,GAB1,C1QL1,KPNA5,MGAT3,MOBP,NOVA2,OPCML,RETREG1,PRKAR1B,ZSCAN32,RAB3IL1,SH3TC2,PAQR6,MAPK12,CSRNP3,SLC1A3,SLC1A7,LIMS2,CCDC88A,SS18,CEP68,SZT2,CHST8,CABIN1,WIPF1,XRCC4" Drug 4364_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ACTN2,AP2A2,ALK,MRTFA,PPP4R4,ATP2A2,SYNJ1,SGCE,CACNA1D,CAMK2B,CAMK2G,CDH18,ADGRG1,CHRNB2,CNTFR,CPS1,SH2B1,DAPK3,DBT,DMPK,FCF1,EIF4G2,DMTN,LRRC23,FGFR1,PRELID3A,TRAF3IP2,INPP5K,SRCAP,GRIK5,KCNN2,MAP4,ZNF862,RETREG1,POLG,POU3F2,GRAMD1C,ZSCAN32,FAM120C,NKAIN1,CCDC40,C1orf54,RASA3,SH3BP2,BCAN,BTBD7,ZBTB43,ARC,SEMA4A,PSD3,ZFP37,SYNC" Drug 7030_UP "Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "SYT13,DNAH17,GYG2,CA4,CACNA2D2,SLIT2,RCHY1,CRY2,APPL1,RIMS2,GIT2,SV2A,DLG3,SLC12A6,EDNRA,EFNB3,PLEKHO1,ZNF589,FGFR1,TRAF3IP2,GAD2,HBS1L,GFAP,GPER1,GRB10,ELOVL5,IPO5,LSS,MID1,GIT1,LYRM9,ZNF862,NDUFA5,NF1,PDE3B,PLEC,PRKAR1B,WDR25,RAD52,ZDHHC14,RGS4,FOXRED2,SELL,ZNF821,RBM34,ZSWIM8,ACSBG1,SYP,AHCYL2,CABIN1,FAM155A,PLPPR2" Drug 4086_UP Trimethadione [127-48-0]; Up 200; 28uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ACTN2,ADRA1D,AGT,AQP4,RGS11,SCAPER,BAIAP3,CAMK2B,CDH8,CSF1R,MICAL2,RIPOR2,RIMS3,C2CD2L,DTNA,RASGRP2,CEND1,CAMSAP1,HBS1L,DISC1,RAB30,LILRA2,GPR17,SOX21,ELOVL5,KCNB1,VWA5A,TAGLN3,NCAM1,NF1,KCNK10,PALM,PBX1,PDE4B,ENPP2,PLCD1,PPARA,CNNM2,BCAS3,PTN,PTPRN2,KCTD17,SEMA6D,RPH3A,SNCA,TNIK,ARHGAP26,VAMP1,TEX15,TK2,TNS1,ZNF225" Drug 4843_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ARID1A,AP2A2,FAM131A,PPFIA3,ARHGDIG,BRINP2,GYG2,BTRC,CA4,CACNG1,CAMK2B,CAMK2G,CACNA2D2,AKAP7,EDRF1,SGSM2,DUSP9,EDNRA,PLXNC1,MTSS1L,ERCC2,SCML2,DLC1,KAT8,ZNF589,KHDRBS3,CSPG5,GNG4,STON1,LPAR4,EML4,PCLO,INPP5B,KCNH2,SMAD1,TM6SF1,PDE4B,RETREG1,PPARA,SAMD9,RAD52,RGS10,PPP1R9A,PREX2,CDK5RAP2,KIF13A,CDK19,ROBO3,RUNDC3B,ZNF45,EMSY,TIGD6" Drug 1869_UP Naproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ACTN1,ALK,MRTFA,BIN1,CDC42BPA,KCNAB2,APOC1,NCOA1,BMP7,CA12,MAP7,CBFA2T2,FOXN3,DNAJB5,RUBCN,TUBD1,DMTN,ZNF589,CAMKK2,BTN2A1,IFI16,VWA5A,MAP4,N6AMT1,MAPK7,RIPOR1,RAP1GAP,ZCWPW1,GSTCD,SEC14L1,SH3BP2,SLC2A5,FAM214B,RAB3GAP1,WDTC1,IZUMO4,TROVE2,SS18,VAMP1,VPS13A,EXOC7,TBL1X,SIN3B,SYNE1,PSD3,KCTD2,TNNT1,TPM1,VAV2,EMSY,PHTF2,ACTR3B" Drug 2169_UP Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "NDRG2,ADD2,BCAR3,CDC42BPA,ANK3,APBB2,DNAH17,ASPH,MAP7,SLC16A4,CBFA2T2,SOCS6,CHRM4,B4GALT6,ABCG1,CRYM,AATK,SIPA1L1,EDRF1,DAPK1,MFAP3L,EDNRB,ELN,EIF1,ERBB2,SCML2,FLT1,SEPT9,GPM6B,PCLO,KCNMA1,KIT,MYO6,NOVA2,PDE4D,PLCD1,PPP3CC,BCAS3,ZMAT4,SEC14L1,SLC11A1,SPTB,IQSEC2,ZBTB43,STX1A,TBCEL,RPGRIP1L,ATP13A2,RPRM,FLRT1,SPHK2,SYNC" Drug 6620_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ADGRF5,ZSCAN18,ATP6V0A1,ADAM23,ADGRB2,BMPR1B,NRXN3,AKAP6,MYRIP,ENTPD4,NCOR2,VCAN,PDE4DIP,PARD6A,ATN1,EDN3,HIPK3,TNK2,NCALD,CEND1,DLC1,FGF1,NSG1,OGA,CHL1,GCK,GRM7,HRH3,ITIH2,KITLG,ADAM22,OLR1,PALM,CAMKV,PLXNB1,CCDC40,C1orf54,GAL3ST4,RGS3,SLN,SOX2,HECW1,BEX1,PCDHGA10,DOCK9,TEX15,PIK3R5,SEZ6L,LILRA4,AMOT,PARP6,MVB12B" Drug 2652_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "AP2A2,EPB41L5,PPFIA3,CDC14B,MARCH3,NCOA1,CFLAR,MAP7,PLEKHB1,ZFYVE9,SOCS5,RABGAP1L,EFNB3,SUGP2,IRAK4,AGAP2,CSPG5,SYT17,MALT1,POLL,GPER1,HNMT,MAP4,MAPT,MMP16,SLC11A2,PC,PDE4A,ELOVL2,PTPRG,PEX5,RAD52,RGS3,ROM1,ZNF821,FBXO11,SMTN,MAPKBP1,SNCA,CDK19,ZBTB43,TROVE2,FCHO1,NCDN,PHLDB1,EXOC7,TIAM1,ZMYND8,VGF,XRCC4,PCBP4,MPPE1" Drug 6324_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "AP2A2,MTUS1,EP400,PPFIA1,KCNAB2,APLP1,ATM,ATP2A2,SLC25A14,TAOK2,CLU,QKI,IQCK,CHD1L,NCOR1,ARHGAP32,GIT2,TNK2,VPS13B,ERCC2,DENND4A,SPEG,ST3GAL6,FCGRT,USP21,GART,MAP4K5,HNMT,MAN2A2,SCAMP5,MITF,MT1M,SLC11A2,NUCB1,OCRL,PIK3R1,POLG,RIPOR1,RAB3A,ARHGEF10L,MAPK12,PEX26,KDM4C,SRPK2,STX1A,GSE1,KIAA0930,PARD3,WBP2,ZKSCAN5,HIRA,EPM2A" Drug 6628_DN Glimepiride [93479-97-1]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.21E-04 1.00E+00 1.24E-03 1.41E-02 52 200 "ADRA1D,AMPD2,PDE8B,DNAH17,RIPK1,KIF1A,CDK5R1,MYRF,CBFA2T2,PICK1,WHRN,CPS1,HAPLN1,NCOR2,CSNK1E,PDE4DIP,TOX,TBC1D5,C2CD2L,EXOG,CDON,EGFR,ZNF589,PNMA2,DENND2A,INPP5K,ZNF276,GLS,GPM6B,LPAR4,GPR37,GRK4,GUCY1B1,SYNPO,MAPT,CNOT4,NUMA1,PIK3R1,STRN3,PRKAR1B,MAPK7,FAM184A,MYH14,ZNF821,SMARCA4,COLGALT2,SS18,MAPK8IP3,WBP2,ZKSCAN5,NDRG4,NAV3" Drug ctd:D003975 Diazepam CTD 1.24E-04 1.00E+00 1.27E-03 1.44E-02 25 75 "SLC12A5,SLC22A6,CNR1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG2,GAD1,GAD2,NEFH,HCN1,PDYN,PENK,MAPK3,MAPK8,SLC1A3,SLC6A11,TAC1,TGFBR3,TRH" Drug CID000003496 glyphosate Stitch 1.25E-04 1.00E+00 1.28E-03 1.46E-02 55 215 "LGR5,PTCH2,CHRD,ASTN1,BMP7,BMPR1B,BTRC,CDO1,TIGD7,NOG,FOXN3,CRYBB1,ST18,BOC,KIAA0586,DLX1,OLIG1,EN2,OLIG2,GPHN,FGF13,FGFR1,FGFR3,FOXF2,FOXM1,TBR1,ATP8A2,GBX2,GCK,GLI2,MAP4K5,IGF1,RBPJ,DISP2,LSS,NHLH1,NKX2-2,PAX6,PTCH1,PTHLH,PTX3,HKR1,KIF7,SALL1,KIF27,DZIP1,SPP1,KIF1B,TAF9,HHIP,RIMBP2,WNT7A,ZIC2,ZFP41,VANGL2" Drug CID000023991 xenon Stitch 1.26E-04 1.00E+00 1.29E-03 1.46E-02 28 88 "BRAP,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA1A,CNOT8,CLTC,NR1D2,ATN1,AFF2,ATP2C1,JPH4,ATP8A2,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,GRM3,ITIH2,MBP,FXYD1,PMP2,MAPK12,PDZRN3,JMJD6,ARHGAP9" Drug 5612_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.27E-04 1.00E+00 1.30E-03 1.48E-02 47 176 "APBB2,PDXK,MARK4,BCL7A,CA12,CAMK2G,CRLF1,ZFYVE9,NMT2,ATRNL1,PDE4DIP,MFAP3L,SACS,KBTBD11,HIPK3,RBM12,EGR3,RACK1,FECH,FGF12,CAMSAP1,CGREF1,GAB1,GPD2,KCNJ3,KHK,LSS,MAP4,MBNL1,KITLG,MMP16,NACA,PDCD2,MBOAT7,RAB3IL1,ATG16L1,RGS10,ZHX3,CDK19,ASTN2,KIAA0930,ZMAT3,CABIN1,METTL3,REEP1,SLC38A1,NETO2" Drug 2485_UP "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.27E-04 1.00E+00 1.30E-03 1.48E-02 47 176 "SLC12A5,GRAMD1B,MTUS1,C1QTNF1,BIN1,FAM131A,DNAH17,DDX3Y,ATP2B2,CFLAR,BTRC,CD86,CBFA2T2,CD38,CHN2,CHRNA4,COL9A3,CREM,CRMP1,MICAL2,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,KIAA0513,SHANK1,DTNB,HIPK3,FAM13A,BAIAP2,AGAP2,GAP43,KCNH1,KCNQ3,NINJ2,OLR1,PDE4B,PDE4D,PID1,SGK1,TNIK,SPTAN1,TACR1,ZFPM2,TPM4,LMF1,PRDM10" Drug 6439_UP "trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.27E-04 1.00E+00 1.30E-03 1.48E-02 47 176 "ABAT,ADRB2,APP,ARNTL,ST3GAL5,CHN2,CRY2,ABCG1,PDE4DIP,CTH,DNAJC6,C2CD2L,PLPPR4,ANKRD46,EFNA3,PTK2B,TAOK3,ATP8A1,BAIAP2,SORBS1,PNMA2,FYN,GLRB,GLS,GUCY1B1,KCNH2,KIF5C,PCDH9,SERPINI1,PIK3CD,PTPN13,RGS4,RPS6KA2,SH3GL3,KIF16B,WDR47,SPTAN1,THSD1,ELOVL4,RGL1,SYT11,SYT1,RUNDC3B,SSBP2,DNAJC12,EVI5,DPF3" Drug 3106_DN Chrysin [480-40-0]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-04 1.00E+00 1.33E-03 1.51E-02 48 181 "ADORA3,MTUS1,MRTFA,AMPD3,CDK10,ARRB1,MARCH3,NCOA1,FUBP1,MAP7,CX3CR1,HDAC9,LPAR6,TUBD1,GPHN,EPS8,ERCC2,ZNF589,KIAA1109,PCYOX1,SYNCRIP,POMT1,PDLIM5,INPP5K,GART,MSL3,ATXN2L,AGBL5,IRF8,IFI16,ITGA7,KCNN2,VWA5A,NEK1,OGG1,PDE4B,PTAFR,HSPA4L,ARHGEF40,WDTC1,SPTAN1,ZC4H2,KLHL7,TCF4,SYNE1,PARD3,ZBTB14,ATP6V0E2" Drug 1613_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.30E-04 1.00E+00 1.33E-03 1.51E-02 48 181 "ALCAM,AMT,MAP4K3,DNAH17,ATM,SYNJ1,CD86,CD38,ARHGAP33,CHN2,MICAL2,PPP1R16B,DOCK4,TM9SF4,TRAPPC9,FAM13A,EGR3,ENO2,RASGRP2,IGSF6,VPS26C,PRKAG2,SRCAP,MUM1,GIT1,OLR1,PDE3B,SSH1,SMOX,MINDY2,MAPK3,SAMD9,PTK2,PTPRE,USP47,RAP1GAP,ATXN2,SGK1,SLC6A8,ARHGEF40,MAPKBP1,WDTC1,ZBTB43,THSD1,EPB41L3,SLC44A1,TK2,REEP1" Drug ctd:D004051 Diethylhexyl Phthalate CTD 1.31E-04 1.00E+00 1.34E-03 1.52E-02 317 1673 "SERPINA3,ACADM,ACLY,ACTN1,ACTN2,NDRG2,BRAP,ADORA2A,ADORA3,ADRA1B,AP2A1,AGT,NR0B1,PLA2G6,LRRC7,KCNT1,DOC2A,AMH,DPP10,PI16,ANXA7,KCNAB2,ARNTL,ARRB2,ASGR1,ASPA,DACT3,NCOA1,DYNLL1,ALDH4A1,ATM,ATP1A1,ATP2A2,CFLAR,LDHD,NAE1,CACNA1I,CACNA1G,GPC2,BSN,MYRF,CA4,CACNA1A,CACNA1B,CACNA1D,CALM1,NGB,CAMK2B,CAMK2G,HIP1R,CBS,SCARB1,CD81,MYOM2,CDH2,CDH8,CDO1,UBE2L6,NPIPA1,CHGA,PLEKHB1,ZBED5,DLGAP3,NRXN1,NRXN2,CLU,CLTB,FADS2,ABCG2,HECTD1,CNR1,WHRN,PNKD,RNF14,SLC32A1,GDA,CST3,RASGEF1C,CX3CR1,GPRASP1,HDAC4,DBI,DBT,DCC,ARMCX2,SPATA2,DNAJC6,MAGI2,SV2B,SPOCK3,G3BP2,DLG4,DMPK,DPP6,DPYSL2,DRD1,ACOT8,SNX29,EDN1,EDNRA,EDNRB,CACNG7,YAF2,EGFR,EIF4G1,SORBS3,ING4,ELN,CALCRL,USPL1,RCAN2,ERBB2,ERBB4,AMZ2,FABP7,CACNG2,TUBA1B,TUBB3,CHST15,FCGR3A,TOMM40L,FDFT1,MAD2L2,ATP5PD,FOLR2,SMC2,NSG1,FUT9,FYN,GABRA4,GABRB1,ILDR2,GAD2,GALR1,GCK,GDF9,GFAP,MMADHC,GFRA2,PPARGC1A,DHRS4,NTNG2,GLI2,GLS,KDM2B,PCSK1N,GNAS,GPM6A,CCDC184,GPR19,GPER1,TUBA1C,RAPGEF4,STMN2,TPPP,GRIA2,GRIA4,RFFL,GRIK1,GRIK2,GRIN1,NR3C1,GRM2,GSN,GSTM5,IL1RAPL1,GSTT2,MFSD2A,RNFT2,WIF1,MAEL,ELOVL5,HMGCL,HMGCR,HNRNPK,HP,HSD17B1,HSP90AA1,SMAP1,MYLK2,IGF1,IGFBP1,ZIC5,SCIN,TUBB2B,ITGA7,KCNK1,KCNMA1,KCNN2,KCNN3,KIF5C,KIT,LIFR,FGFBP3,LSS,MAPT,MAT2A,ADAM11,AFF1,MMP17,MT1M,NRBP2,MTTP,MYH6,MYL3,NCAM2,NF1,NFIA,NFE2L2,NRCAM,NTRK2,NUCB1,NUCB2,OPRL1,PALM,PAX6,PDGFRA,PDPK1,ABCB1,PKM,JAKMIP1,PCDH18,PLTP,ASPDH,PPARA,PPP2R5C,RANBP3L,PKIA,MAPK3,FITM2,PRODH,RELN,PSMA6,MDGA2,PSMD13,PTCH1,PTH1R,PTPRB,PYGM,RIPOR1,ACSS3,ROGDI,RASGRF1,DUSP15,MRPS18A,ROBO1,RIMKLA,SYNDIG1,MEG3,RXRA,RYR1,SCN2A,SCP2,HES6,HSPA4L,FAM102A,ARX,DOCK10,NTNG1,NLGN1,NUBPL,SLC1A2,SLC1A6,SLC6A9,YPEL4,SHANK2,SLIT1,SCN3B,SOX5,KDM3A,NMNAT2,HECW1,SPP1,UNC5B,SSTR1,SSTR2,STXBP1,NECAB1,SYP,TACR1,SATB2,PCDHB15,RALYL,VWCE,TF,ZFPM2,THBS4,SLC44A1,FBXL16,HEY1,TMPO,TNS1,TPM1,TPM2,STXBP4,TRPS1,TSC1,TSC2,TTC3,TUBB2A,CADM1,RPRM,UBE2H,UBTF,DNAJC12,FLRT2,WIPF1,MKRN3,ZBTB16,TUBA1A,SIGLEC10,PCDH15,FAM47E,MPPE1,AMN1,MRPL47,AP3B2" Drug CID000005053 Pyrethroids Stitch 1.31E-04 1.00E+00 1.34E-03 1.53E-02 24 71 "ACHE,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,CALM1,CHGA,ASIC3,QKI,DMPK,ENO2,DMTN,IGSF6,ATP2C1,GFAP,PPP3CA,PPP3CC,SCN4B,SCN3B,SOX10,SYP,CABIN1,CAMK1G" Drug 4707_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-04 1.00E+00 1.36E-03 1.55E-02 49 186 "RALGAPA1,NME5,KCNAB2,APBB2,APC,CDK13,PDE8B,UBE2L6,SOCS6,TPP1,CSF1,FAM169A,PARD6A,ATN1,DTNA,SIDT2,EIF4G2,EN2,NCALD,RRAGB,FGF13,FOXG1,GAD1,SIGLEC8,NEU3,GLYR1,TDRKH,GPER1,GSN,KCNJ3,MBNL1,KITLG,MID1,STRN3,MAPK8,ATG16L1,C1orf54,CARF,PNMA8A,ZFP2,MRAS,RASA3,ZC3H13,AJAP1,KIAA1107,WSCD1,SEZ6L,ZNF24,SEMA3B" Drug CID000010430 isovalerate Stitch 1.35E-04 1.00E+00 1.38E-03 1.57E-02 40 143 "ADAR,PLA2G6,SEMA6A,PLA2G4C,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNG1,MAP7,CACNA2D2,SUMF2,PNPLA8,BOC,DRD1,CACNG7,CACNG3,CACNG2,PTK2B,TNRC6A,GRIK1,GRM7,MSRA,PKD1,GPSM2,LAMA1,HUNK,RYR1,RYR3,SCNN1D,TSPYL2,ST5,TPCN2,DICER1,ZIC3" Drug 448_UP trichostatin A; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "ABHD6,ADD2,ARNTL,MARK4,CA12,HIP1R,NEURL1,PREPL,ABCG1,ARHGEF10,CTH,SNPH,DAPK3,CTIF,PLPPR4,RGS17,TAOK3,BAIAP2,PDLIM5,FYN,GLS,STON1,GUCY1B1,VSIG4,HAPLN2,AGFG1,KIF5C,LIFR,MAP2,TM6SF1,MEF2C,MMP17,RETREG1,SMOX,MBOAT7,SYTL2,ASAP3,SLA,ELMO2,PALLD,TNIK,UNC5B,ZC3H13,ARHGAP26,CDK19,CEP68,PLCB1,AHCYL2,TGFBR3,DNAJC12" Drug 6693_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "AGT,SPARCL1,BCAS1,ATP1A3,CFLAR,SCAPER,CACNA2D1,MTMR7,ADGRG1,QKI,PCYT1B,CSF1,MICAL2,SUSD5,PLCH2,PHF14,CTH,CTNND2,MFAP3L,HIPK3,EFNA3,ATP8A1,ZNF589,FGFR1,SIGLEC8,GLI2,GLS,MDM4,MX1,CNOT4,PDE3B,PIK3R1,LRRN3,PROX1,MARCH1,RGS4,RPS6KA2,RYR1,TMEM156,FRMPD1,FAM214B,CXXC4,ZSWIM8,SPTB,SYT1,CRB1,ZNF24,PRDM10,MVB12B,GAN" Drug 3387_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "AK2,BIN1,APBB2,APC,FAM131A,PPP4R4,RGS20,CFLAR,SYNJ2,GYG2,USP2,CRLF1,RCBTB2,WHRN,MFAP3L,DMPK,EFNB3,PLXNC1,SPEG,FGFR1,CAMSAP1,FHL1,SCARA3,CGREF1,OGA,SRCAP,RND1,GLS,VWA5A,PRKAR1B,PRODH,KCTD17,TCP11L1,RASA3,ASAP3,SMTN,BTBD7,WDTC1,ZHX3,INKA2,ELOVL4,ARHGEF12,DICER1,ZNF34,TMOD1,RUNDC3B,VIPR2,KLC2,REEP1,SSPN" Drug 7342_UP Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "NME5,ARHGDIG,MARCH3,CADM3,BCL7A,BAIAP3,KYAT1,CCNT1,USP2,NEURL1,LRIG1,FAM169A,GREB1,EDRF1,NOS1AP,GNE,DTNA,MAMLD1,EGR3,EZH1,OLFM1,IQCG,MALT1,RUNDC3A,PADI2,ATXN2L,ELOVL5,JAK2,PALM,SMOX,LRP12,PRODH,RAD52,RET,RGS12,ZFHX4,FBXW7,ZNF821,SGK1,KIF16B,SYBU,RBM34,KDM4B,SOX3,SPTAN1,AP4E1,CDK20,MICAL1,NAV2,SSPN" Drug 2911_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "BIN1,APBB2,EPB41L5,BCAS1,ATP6V0A1,KALRN,CBFA2T2,CDO1,CLCN4,SULT4A1,COL9A3,CSF1,MICAL2,SIPA1L1,FAM169A,CTIF,EFNA3,AFF2,GPR153,RND1,GLRB,GRIA4,GRIK5,HMGB1,TJAP1,ITIH2,SCAMP5,GIT1,MSI1,ADAM22,ZNF862,NRCAM,PDE4B,PFKFB4,NLE1,EPN1,NECAB2,SH3BP2,BCAN,WDTC1,ARHGAP26,RBM26,RAP1GAP2,ATP10B,SYT5,TAL1,CRTC1,AHCYL2,KLC2,PCBP4" Drug 2824_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "ADRA1D,BIN1,APBA2,APC,ATM,BACH1,CFLAR,CAMK2B,NEURL1,UBE2L6,ZFYVE9,QKI,AKAP5,MFAP3L,MAGI2,TMCC2,DLG3,SGK2,HIPK3,SORBS3,NCALD,BAIAP2,OGA,FYN,TMEM8B,MSL3,GRM1,GSN,IL6ST,KCNH2,MAOB,MITF,CNOT4,CLDN11,MBOAT7,MAPK8,MAPK10,RAB3IL1,C1orf54,RPS6KA2,EMID1,ASAP3,PREX2,PEX26,SLC14A1,SOX2,MAPK8IP3,ZMYND8,SPHK2,SENP7" Drug 6744_UP Metergoline [17692-51-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "PLA2G6,LTBP4,APBB2,GAS7,SLC4A4,CFAP410,CALB1,MAP7,SYNGR3,CLTB,SLC4A7,IFFO1,HAPLN1,AATK,CTH,KIAA0513,ARNT2,EDIL3,HIPK3,COQ7,F5,CORO2B,TRMO,GATM,GPM6B,ELOVL5,HSD17B1,IGFBP1,KCND3,KITLG,ADAM22,MT1M,NCAM2,NPPA,RETREG1,FA2H,ELOVL2,PTPRH,RGS4,RGS12,ZFP30,CNKSR2,TNIK,TROVE2,MAPK8IP3,SYN2,SYT5,TK2,R3HDM1,KCNAB1" Drug 1418_DN Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "ACADM,CLK4,AMPD3,SHTN1,ATM,ATP2B1,CFLAR,CANX,CCNT1,CHD1L,HDAC9,MATR3,DBT,DMTF1,LPAR6,KCTD3,EPB41L2,CEND1,KIAA1109,SUCO,SEC23B,TRMO,MALT1,NR3C1,AGFG1,JAK2,MBNL1,PFKFB3,TRHDE,MED1,PPM1B,CNNM2,C1orf54,REV3L,PCMTD2,CLIP1,BCAN,PEX26,CCDC88A,ZCCHC24,CLUAP1,NXT2,ANKRD12,TCF7L2,TPD52,METTL3,ELP5,ZNF24,ZNF189,ST7" Drug 7486_UP CP-319743 [172078-87-4]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.35E-04 1.00E+00 1.38E-03 1.57E-02 50 191 "LTBP4,APBB2,APOC1,ARRB1,N4BP2L1,ATP6V0A1,ADAM15,MTMR3,GYG2,LDLRAD4,CAMK2B,NEURL1,ARHGEF2,LHX2,CRMP1,CRYM,SUSD5,CHD5,VCAN,EDRF1,TBC1D5,DGKG,HP1BP3,FEM1B,SPEG,AGAP2,GLYR1,GPER1,GRB10,NR3C1,GRM1,MMP17,NF1,PDE3B,NECAB2,PRKCB,SEMA6D,SLC6A8,SLC6A9,SLC9A5,BTBD7,SNCA,KIF21B,VPS13A,WSCD1,TRIM2,TRIO,TRPC1,KCNK12,SENP7" Drug 4420_UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "SYN3,ADCY6,ADRA1D,LTBP4,GAS7,CDC14B,RASL11B,ADAM23,AZGP1,BAIAP3,LDLRAD4,CACNA1D,CHRNA4,RGS6,BRINP1,DLG4,DRD1,EDN3,MBNL2,TNK2,ELAVL4,F5,KIAA1109,FHL1,ZNF44,IL1RAPL1,HPSE2,IRF8,MDFI,MYCN,NCAM1,NEFM,NF1,PDE1C,GPR85,PLXNB1,KHDRBS2,KLHDC8A,SYNDIG1,LIMS2,PKNOX2,SLC6A9,RIMS1,SNCA,HECW1,SPTB,PLCB1,TRPM2,WIPF1,SLC30A3,DPF3" Drug 2033_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADORA1,APBA2,APC,MARK4,RASL11B,SLC4A4,N4BP2L1,BCL7A,CFLAR,MTMR3,MTMR2,CHRNB2,FADS2,CRY2,B3GAT3,RABGAP1L,ING4,LRRC23,FGFR1,OGA,SRCAP,GDF9,AHDC1,GJB1,OS9,MCHR1,SLC2A6,TJAP1,KCNB1,KCNH2,SCAMP5,MMP17,MYT1,NFYA,NOVA1,OCRL,PDE1C,GON4L,RLBP1,GALNT10,ELMO2,TSNAXIP1,SRPK2,TBL1X,TCF7L2,OBSL1,SEZ6L,TPM3,WBP2,CHST5,CAMK1G" Drug 987_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADRA1D,TRMT9B,BIN1,CDC42BPA,APC,GAS7,ADAM23,BAIAP3,LDLRAD4,TPP1,COL9A3,SLC4A8,ARHGEF4,RABGAP1L,DYRK1A,ST8SIA3,EDN3,EIF4G2,HSD17B14,MTSS1L,GLS,GNAL,GRM1,ATXN2L,LAMA2,LMO2,ZNF862,NCAM1,NUMA1,PPARA,MAPK8,MAPK10,SAMD9,ZSCAN2,RGS10,SUGCT,SH3BP2,FAM214B,SLC9A5,SNCA,RBM34,KDM4C,ATP11A,OBSL1,TNS2,FAM155A,ZNF45,SLC17A7,PARP11,FAM13C,TIGD6" Drug 1267_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "C1QTNF3,BCAR3,BBOX1,CDK10,CAPN3,SLC16A4,CDH10,NMT2,IQCK,ARMC8,RNF14,G3BP2,DTNA,ABI2,COQ7,MTSS1L,ST3GAL6,EFCAB2,CINP,CGREF1,ZNF44,LYVE1,KCNMB4,LILRA2,LPAR4,PADI2,DHX35,LSS,NINJ2,PDE3B,CDIP1,RELN,BCAS3,PTAFR,PTCH1,RET,SEC61A2,SEC14L1,LIMS2,PKNOX2,SLC12A2,EMC1,PLCB1,KIAA1107,SIN3B,CHST8,KCTD2,TNS1,TPD52,CDK20,TFIP11" Drug 3842_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DOC2A,BIN1,APP,MARK4,MPDZ,BTRC,CHM,TAOK2,ZFYVE9,TPP1,SLC4A7,AKAP12,CSF1,RIMS2,DAPK3,DNM1,MBNL2,SORBS3,COQ7,NCALD,ZNF589,GAB1,GLYR1,STON1,KITLG,ADAM22,NFYA,PLCD1,PRKAR1B,MAPK8,SNRK,RAD52,ATG16L1,ENOX1,RGS10,RGS12,SH3BP2,ASAP3,FNDC3A,PEX26,WDTC1,MAPK8IP3,TTBK2,PLCB1,RPGRIP1L,ZKSCAN5,FAM155A,SNX27,ST7,PHTF2,RNF146" Drug 2922_DN Epitiostanol [2363-58-8]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ABAT,NDRG3,GRAMD1B,MRTFA,AMT,PPFIA4,ADAM23,BCL7A,SCAPER,CAPN3,SLC16A4,AKAP7,IQCK,CSF1,OSBPL3,DZIP3,EDRF1,EXOG,FEM1B,OPTN,ABI2,ZNF589,GALC,SRCAP,USP19,COPS8,PCLO,CACFD1,PADI2,MAP4,MDM4,SLC11A2,NUCB1,PKN2,PLPPR3,MYH15,ATP11A,KAZN,CAMSAP2,RPGRIP1L,PSD3,AHCYL2,TPM1,TPM3,TRPS1,SSBP2,XRCC4,ZNF32,ZNF225,MAP3K12,NLRP3" Drug 6557_UP AG-028671 [847803-03-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ALAD,APBB1,APP,CDK13,CCNT1,CDC42BPB,HINFP,PLCH2,FAM131B,ARHGAP24,GIT2,SORBS3,MRNIP,CDKL3,ETV1,FGFR3,FYB1,INPP5K,C1QL1,GLYR1,GRK4,SOX21,PADI2,BACH2,IL12A,JAK2,KCNJ5,MAPT,MIA2,SLC11A2,PRKAR1B,PTPRH,RAD52,PPP4R3A,LIMS2,WDTC1,KDM4C,ARHGAP26,ZBTB43,CEP68,ASTN2,EXOC7,KIAA1107,TCF4,TNS2,SLC35G2,TK2,TPM2,SPHK2,MPPE1,PLSCR4" Drug 3568_DN Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AK2,APBB2,APC,PPFIA3,MARK4,ALDH4A1,CFLAR,CA12,CACNB2,SLC4A7,ENTPD4,SH2B1,MICAL2,PPP6R2,DTNA,EGR3,WAC,ANKFY1,TPK1,PRELID3A,AHDC1,USP19,CNTRL,BTN2A1,HSD17B1,IGSF1,KHK,KIF5C,ADAM22,CNOT4,PDE4A,RETREG1,PRKAR1B,GON4L,ROM1,WLS,AMBRA1,SCMH1,SOX3,EMC1,POGZ,EXOC7,IQCE,TCF7L2,TRIM2,CRTC1,ATP13A2,TMEM121,AP4E1,TPM1,SSPN" Drug 874_DN (-)-depudecin; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "CLK4,NDRG3,BRAP,OSBPL1A,BIN1,ANK3,PKP4,CDK10,ATM,BCL2L2,REPS2,QKI,NIPBL,CSNK1E,SDC3,USP6NL,GIT2,DMTF1,FCF1,MRNIP,FGFR3,NOP56,FAM49B,INPP5K,ZNF276,MSL3,NAP1L1,NASP,NEK1,NFYA,CNOT4,CCSER2,RETREG1,NLE1,STRN3,ING3,RAD52,ROBO1,MCMBP,ITSN1,ZNF430,SLC15A2,ZHX3,ZBTB43,SS18,TCF7,TCF7L2,KAT6B,NSD2,MVB12B,GAN" Drug 4714_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,ADCY2,KLRC4,NME5,LTBP4,ATM,CFLAR,ST3GAL5,CFAP410,CHD1L,ENTPD4,GREB1,MAML1,ATN1,RASGRP2,ZNF589,GABRA2,USP19,CACFD1,GRM7,IL6ST,KCNJ3,KCNJ5,KCNMA1,MAPT,MID1,NEFM,CNOT4,NOVA2,PDE4B,PLCB2,PTHLH,RAD52,TTLL7,ROM1,SYBU,THSD1,ELOVL4,TTBK2,PHLDB1,POPDC3,DOCK9,PCDHA6,TMOD1,ZMYND8,UBE3A,WIPF1,ZNF24,WNK1,PRDM2,NT5M" Drug 5642_DN Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ARID1A,NDRG2,SLC12A5,NME5,PLA2G6,KCNAB2,PPP4R4,SCAPER,CACNA1I,CLGN,RCBTB2,FOXN3,STOML1,SULT4A1,RCHY1,PDE4DIP,CTH,EFNA3,IGSF6,SCML2,KIAA1109,FHL1,FOXG1,AFF2,GLYR1,GNG4,GPER1,CNTRL,CACFD1,HLF,KCNMA1,KCNN2,AFF1,MMP16,NTRK2,LRP12,PPARA,ELOVL2,ZSCAN32,FERMT1,SLC15A2,COA1,SMARCD3,TROVE2,TBCEL,PSD3,CRTC1,PCDHA5,FAM155A,KCNK12,EPM2A" Drug 3530_UP (-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADD2,NME5,PLA2G6,CDC42BPA,APBB2,APC,CADM3,CFLAR,CACNA1D,CACNB2,SCARB1,ARHGEF2,CACNA2D2,CLCN4,AKAP5,SDC3,RIMS2,EDRF1,SEC14L5,DGKG,TMCC2,ING4,DMTN,FHL1,RUNDC3A,GPD2,ICA1,SMAD1,MEF2C,ADAM22,PDE3B,PFKFB2,PACSIN1,RIPOR1,RAB3IL1,RGS12,MRAS,FBXO11,SYBU,SLC1A7,SCMH1,UNC5B,ARHGAP26,PLCB1,EXOC7,PCDHGB6,PSD3,ZMYND8,XRCC4,SYNC,PARP11" Drug 5760_DN Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AK2,ASPH,ALDH7A1,ADAM23,ARHGEF2,CDC42,MAGI1,ASIC3,ARHGAP22,CRY2,PDE4DIP,CNTNAP2,SMG7,DRP2,SIDT2,AASS,EIF4G2,MRNIP,COQ7,LRRC17,FGFR1,SCARA3,OGA,FYN,SEPT9,ZNF276,GNG3,TDRKH,DHX35,MAP4,MAPT,ADAM22,NASP,NDP,CNOT4,ODF2,PENK,NLE1,KCTD17,SLCO1A2,MAPK8IP3,VAMP1,PLCB1,ASTN2,METTL3,TRPC1,HIRA,WIPF1,NSD2,NT5M,EVI5" Drug 6469_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AK2,PLA2G6,LTBP4,AMPH,BIN1,APOC1,MARK4,ALDH4A1,GYG2,CALB2,ARHGEF1,LHX2,ZFYVE9,COL9A2,CNTNAP2,NOS1AP,HP1BP3,LYPD1,SMG7,EDNRA,SIDT2,EFNA3,EFNB3,MSL3,GOLGB1,VWA5A,MPP2,ZNF862,NELL2,NF1,NFYA,NPTX1,OGDH,PDE3B,PDE4A,PPP2R5C,TMEM104,WDR25,RAB3IL1,KHDRBS2,SMTN,CXXC4,ZHX3,ZNF423,TROVE2,TTBK2,TRIM2,HIRA,UBTF,VAV1,URM1" Drug 4392_DN Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASPHD1,CDK13,ASPH,CACNA1I,CBFA2T2,CDC42,DNAJB5,TCEAL2,SPOCK2,DBT,RUSC2,DMPK,SLC12A6,LRRC23,FOXG1,GPR153,RAB30,CNTRL,SPACA9,HSF2,INPP5B,KCNN1,KPNA5,MOBP,ADAM22,NEUROD1,NF1,NFYA,CNOT4,STRN3,MAPK8,RAD52,C1orf54,NEK11,WLS,FNDC3A,SLC9A5,KDM4B,TSNAXIP1,TROVE2,PLCB1,ROBO3,IQCE,WSCD1,PARD3,HIRA,CADM1,FLRT2,ZBTB14,EMSY,SEMA3B" Drug 7527_DN CP-645525-01 [287190-82-3]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "BRAP,NME5,CBFA2T2,ARHGAP22,ZFYVE9,KIAA1549L,FAM169A,DZIP3,GPRASP1,DTNB,APH1A,EIF5,FGFR1,FHL1,SORBS1,CINP,GLI2,HTATSF1,GPR37,JAK2,MMP17,CNOT4,SLC11A2,PDE1C,PPP2R5C,MAPK7,PTPRN2,TMEM231,RAD52,GSTCD,MRAS,SH3BP2,PPP1R9A,KIF16B,AMBRA1,WDR47,COA1,MYH15,SPTAN1,LARP4,ARHGEF9,ATP11A,PSD3,AHCYL2,CHST5,HIRA,UBE3A,MICAL1,LMF1,XRCC4,RNF146" Drug 3716_DN Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,ADGRF5,ARNTL,CDK13,ARHGEF2,PLEKHB1,CHRNB2,CHD1L,NCOR2,CSF1,VCAN,SLITRK5,CTNND2,KIAA0513,SPOCK3,AK5,CHRDL1,ATN1,RCAN1,DTNA,CELSR3,EIF4G2,ING4,ETV1,FGF1,FGFR1,GNG4,ATXN2L,JAK2,KIF5C,MARK1,NF1,CNOT4,NPR2,NUMA1,GPR85,PIK3CD,SAMD9,SUGCT,PAQR6,SLN,SNCA,DOK5,MAPK8IP3,MLC1,PLCB1,TEX15,VGF,VIPR2,LMF1,UBE3B" Drug 4551_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ACTN2,LTBP4,BEGAIN,CDK13,PTCH2,ST3GAL5,KALRN,CCNT1,SCARB1,SLC4A7,ENTPD4,NCOR2,CSF1R,VCAN,MFAP3L,SMG7,SPOCK3,DTNB,CNNM1,CELSR3,ETV1,CEND1,ZNF589,FGF1,AFF2,DCTN2,OGA,GPR19,ELOVL5,KCNN1,KIF5C,NF1,NOVA2,GRAMD1C,PTPRH,PTPRN2,MARCH1,CCDC40,RGS12,TCP11L1,RASA3,AMBRA1,PREX2,KIF13A,DOP1A,ZHX3,ARHGAP26,TCF4,SEZ6L,TPM1,SSBP2" Drug 4535_UP Parbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,ADRA1D,MRTFA,TRMT9B,PPFIA4,SLC4A4,CFLAR,RUNX1T1,CD86,SEPT7,TCEAL2,MYRIP,FEZ1,CNTNAP2,GREB1,RIMS3,DAPK3,FAM13A,ING4,EFCAB2,GRM8,SOX21,AGFG1,IL6R,INPP5B,JAK2,MT1M,NEUROD1,TREM2,PROX1,TMEM231,CCDC40,C1orf54,RGS10,KLHL11,SNCA,TNIK,BEX1,MAPK8IP3,SYP,PCDHGA10,TIMP4,TMOD1,DAAM2,TPM2,MICAL1,WNK1,PRDM2,PARP6,SCG2,NAV2" Drug 3342_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AP2A2,MRTFA,CDC42BPA,APBA2,PPFIA3,MARK4,CAPRIN2,CFLAR,SCAPER,GYG2,BTRC,ADGRG1,CREM,CRY2,CSNK1E,SIPA1L1,EDRF1,MAML1,DAPK3,PARD6A,RABGAP1L,DTNA,EFNA3,STX2,FER,BAIAP2,PDLIM5,TXNL4A,GNG4,STON1,KCNJ5,LSS,NPTX1,NRGN,WDR25,ZDHHC14,ROM1,SYBU,ZNF365,KIF13A,CDK19,ELOVL4,AJAP1,VPS13A,EXOC7,SMG6,AP4E1,TRIO,TRPC1,REEP1,EVI5" Drug 6648_DN "Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "MTUS1,PLA2G6,APC,CFLAR,BTRC,EPS15L1,NMT2,DNAJB5,HAPLN1,ABCG1,DBT,SPATA2,CNIH3,SMG7,PARD6A,EFNA3,TENM1,EN2,PLEKHO1,DENND4A,ETV1,KIAA1109,FGFR1,TRMO,GAD1,C1QL1,STON1,GRM8,HLF,DHX35,TJAP1,VWA5A,NF1,PCDH9,LRP12,CNNM2,GSTCD,ZNF671,TMEM156,DOCK10,AMBRA1,TNIK,LHPP,TROVE2,NCDN,JMJD6,SYT1,ZEB1,ZNF34,XRCC4,AAAS" Drug 4718_UP Cefamandole sodium salt [30034-03-8]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,ASIC1,NDRG2,CDK13,ATM,CFLAR,CACNA1I,CACNG1,GPR37L1,QKI,CRMP1,CSF1,GREB1,EXOG,ATN1,EDN1,EFNA3,EFNB3,ING4,ELAVL3,RASGRP2,NCALD,RRAGB,KIAA1109,FGFR3,SRCAP,GLYR1,PTGDR2,IL6ST,ITIH2,KCNJ3,KITLG,NEK1,CDK18,NLE1,STRN3,PPP5C,PTHLH,RAD52,GSTCD,ZKSCAN3,OGDHL,LIMCH1,PCDHGA10,PCDHA6,ZNF34,HEY1,LAT2,ZNF24,SEMA3B,SSPN" Drug 373_DN "estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ACADM,ARID1A,NDRG2,CDK10,ASCL1,BMP7,KCNAB3,DLGAP1,CHRNB2,AATK,CSF1R,DZIP3,KIAA0513,DAPK1,RCAN1,SIDT2,EFNB3,PHF20L1,ING4,VPS26C,FGFR1,FOLR2,DPYSL4,TPK1,NSG2,GAB1,GAD2,HPGDS,GPER1,GRIN1,BTN2A1,KCNJ5,KCNJ10,NEK1,NPR2,NPTX1,PDPK1,GPR173,MBOAT7,GAL3ST4,TCP11L1,CLIP1,ASIC4,DOP1A,EMC1,POGZ,STX1A,TACC1,WIPF1,GDPD5,HPS4" Drug 2073_UP Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "CASK,BCL7A,SYNJ1,SYNJ2,MYRF,SPAG9,CNOT8,CLCN3,ABI3BP,NRG2,CTH,DCAF4,GIT2,FCF1,EFNA3,COQ7,VPS26C,HPCAL4,POLL,CACFD1,SOX21,IFI16,SHISAL1,KIFC3,LIG4,MAP4,MMP16,CNOT4,PPP5C,PRKAB2,APTX,PTPN13,RGS4,RGS10,NUDT11,ZFP30,PPP4R3A,SLC20A2,LHPP,TROVE2,LARP4,ATP11A,IQCE,KIAA0930,PSD3,KAT6B,CABIN1,WIPF1,LAT2,SH3GLB2,MAP3K12" Drug 5294_DN Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "OSBPL1A,ALAD,APP,NCOA1,CAMK2G,SCARB1,ENTPD6,LRRFIP1,CHN1,NCOR1,FAM169A,CTH,ARHGAP32,LYPD1,RHOBTB1,DLG3,DNM1,SORBS3,TESK2,FGFR3,ANKFY1,CINP,FAM49B,ATP2C1,ERAP1,INPP5K,COPS8,ZNF638,ARHGAP19,INPP5B,AFF1,SLC11A2,OPA1,PCDH9,STRN3,PKIA,VPS13C,MYH14,LGR4,EFHD1,RCOR3,MAPKBP1,SOX3,ZSWIM8,CEP68,FAM168A,SYT1,TACC1,PSD3,PRDM10,MVB12B" Drug 4123_UP Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "APAF1,ARRB1,ASPH,SYNJ1,RUNX1T1,ARHGEF1,CLCN4,WHRN,CRY2,CNTNAP2,DAPK3,SPOCK2,USH1C,FCF1,EFNA3,EPHB1,CEND1,C1orf61,GFAP,SOX21,HTR2A,KCNMA1,MSI1,CNOT4,CLDN11,PCDH9,PRKAR1B,RAB3IL1,RAB5B,CCDC40,ENOX1,NUDT11,GSTCD,STUM,RPH3A,SMARCD3,LIMCH1,DOP1A,NMNAT2,HECW1,EXOC7,KIAA1107,TBCEL,DMXL2,OBSL1,SLC35G2,PIK3R5,SLC13A3,PRDM10,SLC17A7,SSPN" Drug 3113_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AP1B1,PKP4,KCNAB2,PDXK,ASPH,SLC4A4,ATP6V0A1,BCL7A,LDLRAD4,CBFA2T2,SCARB1,CD38,CLCN3,CLCN4,CNTN1,CREM,EDRF1,ERCC2,ECSIT,PTK2B,SCML2,ST3GAL6,KIAA1109,CGREF1,HTATSF1,CACFD1,SMAD1,MAP4,MATK,MYO9A,NINJ2,OGDH,OGG1,PIK3R1,CCSER2,SLC25A23,ATG16L1,DGLUCY,SATB1,SEC14L1,ANKRD6,TMCC1,ZCCHC24,IQSEC2,KAZN,TNS1,TPM1,UBTF,LMF1,ATP6V0E2,PRDM2" Drug 3930_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ACTN2,AZGP1,CACNA1I,CFAP410,CACNG1,RUNX1T1,FOXN3,STOML1,FADS2,IFFO1,NRG2,DCT,RUSC2,SNX29,SORBS3,ELN,CALCRL,REEP2,CACNG3,FHL1,GAD1,GAD2,NEU3,POLL,STON1,GPR22,GRM7,GUCY1B1,PTGDR2,HTR2A,ITGA7,MEF2C,NEUROD1,NTRK2,PDE4D,NLGN3,PTCH1,RYR1,SCN8A,STUM,CNKSR2,SLC1A7,SNCA,PDZD2,ADGRL3,TEK,THBS4,TMOD1,MICAL1,LAT2,KCNAB1" Drug 6401_UP F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,FZD9,LTBP4,APBA2,APC,GAS7,PPP4R4,ALDH4A1,CADM3,ATP6V0A1,KSR1,CACNB2,CBS,CHRNB2,MFAP3L,CHRDL1,EDN1,PLEKHO1,CDKL3,SORBS1,PDLIM5,FUT9,GABRA2,NEU3,CACFD1,ITIH2,KCNJ5,MAPT,MPP2,SLCO1C1,PFKFB2,LRP12,TNPO2,PPP5C,CEP41,PTPRE,RAB3IL1,KCTD17,TTLL7,MYH14,ATXN7,SH3BP2,ASAP3,SLC6A11,DOK5,DDN,COLGALT2,TBCEL,TIAM1,R3HDM1,KCNAB1" Drug 2668_UP "estradiol, USP; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "MTUS1,SYNJ1,CFAP410,SLC16A4,STOML1,QKI,CREM,ATRNL1,SIPA1L1,VCAN,CTNND2,DCAF4,EDRF1,KIAA0513,ZNF337,DGKG,DBT,SPOCK3,TRAPPC9,HIPK3,VPS13B,FGFR1,CAMSAP1,FHL1,C1orf61,GAD2,GATM,LILRA2,GSN,GPR45,ATXN2L,KHK,KIF5C,KIT,NINJ2,OXTR,PDE4D,PENK,PFKFB2,ABCB1,PPP2R2B,CNNM2,PTCH1,BCAN,SLC11A1,SLN,SMARCD3,TNIK,TCF7L2,ZNF34,TRPS1" Drug 1728_UP DO 897/99; Up 200; 8.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "C1QTNF3,BMP7,CAST,ABCG2,AKAP7,SEC31B,CSF1R,MICAL2,ARHGAP32,DBT,KIAA0753,DPH1,ATN1,EEF1A2,SIDT2,ELAVL4,RASGRP2,KIAA1109,C1orf61,SEMA4D,NSG1,ALDH1L1,GNAS,KLF12,KCNH2,KCNN1,CNOT4,NTRK3,NUCB1,PALM,PFKFB2,SMOX,PRRX1,MBOAT7,DEF8,PEX5,C12orf49,ATXN2,SH3BP2,TMCC1,KDM4B,GSE1,SYT1,TK2,TMOD1,TNNT1,SEZ6L,SSBP2,NPDC1,URM1,RNF170" Drug 4257_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "TTYH1,ABAT,NR0B1,ANK1,AQP6,ASCL1,B3GALT2,BMPR1B,MTMR3,CACNA1G,CACNA2D1,BRSK2,SLC16A4,ADGRG1,SLC22A6,NRXN3,DNAJB5,COL9A3,NCOR2,CSF1,USH1C,EDN3,HEYL,FYB1,GABRA5,SIGLEC8,PCDH17,TOX3,IRAK3,GPR45,HAPLN2,HPCA,KCNA2,KCNC1,MBNL1,MGAT3,MOBP,MYH6,NF1,SLCO1C1,NNAT,PPP1R1A,DCHS2,CCDC40,KHDRBS2,RGR,KLHDC8A,INKA2,KAZN,PRMT8,CAMK1G" Drug 1894_UP Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "NDRG3,ADORA1,AP2A2,KCNAB2,APBB2,ASCL1,N4BP2L1,ATP6V0A1,SCAPER,MAP7,CNOT8,CNTFR,CSNK1E,ARHGEF4,SPOCK2,KLHL3,SMG7,TMCC2,SRPK3,TUBD1,STX2,F3,KIAA1109,ATP2C1,GJB1,PRRC2B,GSTM5,NXPH3,IFI16,GIT1,NCAM1,NTRK3,PAK3,RAB3IL1,NUDT11,NCBP3,EPN2,HECW1,UNC5B,CDK19,MAPK8IP3,VPS13A,IQCE,TRPC1,SSBP2,VSNL1,CLIP2,EVI5,PRDM10,SMIM8,NUP214" Drug 1469_UP Dibucaine [85-79-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASPHD1,AP2A2,CDC42BPA,BCAS1,MARK4,ALDH4A1,SCAPER,CAMK2B,CBFA2T2,TENM4,PDE4DIP,DAPK3,MFAP3L,TRAPPC9,EFNB3,LRRC23,FGFR1,INPP5K,POLL,GNG3,TJAP1,KCNH2,MAN2A2,MYO7A,MYT1,SLCO1C1,NUMA1,PACSIN1,PTHLH,PTPRB,PTPRO,TMEM206,STUM,BCAN,FAM214B,SLC11A1,SLC22A4,SLN,BEX1,TSPYL2,SYN2,ARHGEF12,TNS2,CHST8,AP4E1,TK2,CDK20,MICAL1,ZNF45,KCNAB1,NUP214" Drug 6994_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADD3,AP2A2,MRTFA,CDC42BPA,NCOA1,CFLAR,ST3GAL5,BTRC,CBFA2T2,ZMYM4,PLAA,MAP4K4,AKAP12,SOCS5,INTS1,DNAJC6,FBXL5,SMG7,ARNT2,EPB41L2,VPS26C,PRKAG2,POMT1,CAMKK2,B4GALNT1,ZNF276,TXNL4A,FERMT2,NR3C1,KCNF1,NCAM2,NEK1,PBX1,STRN3,MED1,SIDT1,RIPOR1,RGS3,NEK11,SBF1,SH3BP2,ITSN1,RCOR3,USP33,EXOC7,AHCYL2,BHLHB9,SSBP2,UBTF,ZNF24,URM1" Drug 334_DN 6-mercaptopurine monohydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ABHD6,ARID1A,ANK2,GAS7,ASCL1,CADM3,GYG2,BAIAP3,BTRC,CDC27,CHGB,SLC4A7,VCAN,PPP6R2,SEC14L5,C2CD2L,E2F5,EFNB3,EGR3,EIF5,FECH,GLS,GPM6B,GRIA4,MAN1B1,MBD1,MYL3,NAP1L1,CAMKV,PIK3CD,RETREG1,PACSIN1,SIDT1,RGS3,FOXRED2,SH3BP2,ITSN1,FERMT1,FBXO11,KBTBD4,ELMO2,TNIK,KAZN,IQCE,TMEM151B,KCTD2,TMPRSS5,FLRT1,ZBTB14,ZNF142,PRDM2" Drug 4523_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "SYT13,TRMT9B,GAS7,CDK10,ZSCAN18,N4BP2L1,ADAM23,RGS11,BTRC,CACNA1A,NGB,HIP1R,SLC16A4,CBFA2T2,SCARB1,CHRNA4,TCEAL2,CNTNAP2,EGFR,EIF4G2,DLC1,FGFR1,FYB1,ZNF44,RND1,GLI2,GNG4,GPM6B,GPER1,MSR1,NEUROD1,NF1,NOVA2,NRCAM,OPCML,PDE4D,PHKG1,PPARA,ELOVL2,ZCWPW1,RFX2,TMEM206,CCDC102B,DOCK10,SLA,ZNF415,INKA2,ZEB1,TIMP4,TPM2,TRPC3" Drug 5928_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,AMPH,BIN1,ANK3,APC,GAS7,CDK13,SLC4A4,KIF1A,CACNA1I,BAIAP3,ARMC8,TENM4,HDAC9,ETV1,ANKMY1,F3,FOXG1,EFCAB2,GAD1,SEPT9,AHDC1,LPAR4,IFI16,SCIN,IL6ST,AFDN,MSR1,MYO7A,NEK1,NF1,CNOT4,PALM,FRMPD1,DOCK10,SLA,SLC1A7,URGCP,SHANK2,SNCA,LHPP,ZEB1,SLC44A1,BHLHB9,TLR4,TPM2,XRCC4,ZNF711,REEP1,SLC17A7,PCBP4" Drug 903_DN 5151277; Down 200; 14uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASPHD1,ABHD6,CDC42BPA,APAF1,SYNJ2,SPAG9,EPS15L1,STOML1,SMARCAL1,NCOR1,SOCS5,DMTN,LRRC23,MTSS1L,SCML2,FGFR1,FHL1,ATP2C1,GPR153,SEPT9,INPP5K,FERMT2,GPER1,JAK2,KCNJ3,ADAM22,RETREG1,SMIM7,MBOAT7,SAMD9,CCDC25,FOXRED2,SEC14L1,ASAP3,EPN2,WDTC1,EMC1,LHPP,TROVE2,MAPK8IP3,DIP2A,EXOC7,AHCYL2,THRA,TIAM1,CABIN1,TRPC1,RPRM,ZNF24,GDPD5,TIGD6" Drug 341_DN sodium 4-phenylbutyrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "C1QTNF1,BIN1,ANK1,ARNTL,ARSF,ASCL1,CAMK2B,CDH8,CHRNB2,CREM,AATK,DCT,DLG3,DNAH9,EDIL3,PLEKHA1,EN2,ZMYND10,FGFR1,FGFR3,FOLR2,SMC2,NCKAP1,SRCAP,GPER1,DIDO1,SOX21,NXPH3,ARHGAP19,ADAM22,PCDH9,PDE1C,NLE1,PPP2R2B,RAB3IL1,RGS4,RXRG,SAFB,RASA3,FUZ,SLC11A1,AGTPBP1,WSCD1,TCF7,TMEM151B,KCTD2,PARD3,TNS1,SLC13A3,ZNF142,FIP1L1" Drug 4465_DN "estradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "KIDINS220,AMPD3,CDC42BPA,BCAS1,PRX,PPP4R4,CDK13,DNAH17,BMP7,SCAPER,BAIAP3,CACNB2,SLC22A6,CLTB,SULT4A1,PICK1,CRMP1,DMPK,HPCAL4,EFCAB2,HBS1L,KCNMB4,GNAL,GRK4,GRIK5,ITIH2,KCND3,KCNJ5,KCNN1,LAMA2,MDM4,LYRM9,NF1,NTRK2,PIK3CD,PLCB2,MAPK7,ZSCAN32,MYH14,SLA,SLC1A7,SLC9A5,SPTB,DDN,MAPK8IP3,MLC1,TBCEL,THRA,TRIO,SPHK2,MVB12B" Drug 4420_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "NME5,APBA2,MARK4,SCAPER,KRIT1,LARGE1,FEZ1,RIMS2,PPP6R2,EXOG,DTNA,ING4,FER,FGF12,FHL1,FOXG1,SEMA4D,GPR153,DISC1,C1QL1,MSL3,CNTRL,GRB10,NR3C1,INPP5B,KCNH2,TM6SF1,NF1,CNOT4,NUMA1,SERPINE2,SERPINI1,RETREG1,PLCD1,PPP2R2B,RGS3,TCP11L1,ASAP3,FBXO11,EPN2,PHLDB1,PSD3,TK2,HIRA,FLRT2,VLDLR,ZNF45,EMSY,PRDM2,EPM2A,SSPN" Drug 5757_UP Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADD2,ADORA2A,AP2A2,PLA2G6,APBB1,CDK10,CLCN4,RAB26,NCOR2,MICAL2,RIMS3,C2CD2L,DTNA,FEM1B,RCAN2,ZNF549,DCTN2,ERAP1,RAB30,PRUNE2,GPR17,GPR19,STMN2,ATXN2L,HPCA,KCNN2,LAMA2,AFF1,MOBP,PDE4A,CNNM2,ZSCAN32,ZMAT4,NEK11,SYNDIG1,SUPT20H,PPM1E,DZIP1,SLC1A7,SLC6A11,LHPP,COBL,TACR1,PHF24,PCDHA6,CRB1,HEY2,TPM1,TUBB1,VAV1,NUP214" Drug 5593_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADORA1,FAM135A,APAF1,APOC1,DNAH17,ADAM23,AZGP1,CFAP410,CAMK2B,HIP1R,KCNAB3,CLGN,LHX2,ZFYVE9,CNN3,AKAP5,IFFO1,AATK,CSF1R,VCAN,PDE4DIP,SPOCK2,ELAVL3,MTSS1L,DCTN2,DISC1,RND1,GNAL,GNAS,GRIK4,NR3C1,SOX21,HRH3,IFI16,NTRK2,OMG,PDE1C,LRP12,ENOX1,SEMA6D,SCNN1D,SH3BP2,DOCK10,PCDHGB6,TPM2,FLRT2,GDPD5,SLC17A7,KCNAB1,ITM2C,MVB12B" Drug 7506_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AP2A2,BIN1,APC,KIF1A,MTMR2,C5,CA12,SLC25A14,TAOK2,CNTFR,SLC4A7,ABCG1,CSF1R,SOCS5,DMPK,DTNA,SUGP2,FGF12,PRKAG2,GRB10,HNMT,ITPKB,MITF,AFDN,MYCN,NFYA,OCRL,SLC25A23,MBOAT7,TMEM231,RAB3IL1,RAD51D,ZDHHC14,EMID1,IL17RB,ZNF821,ZFP30,BCAN,SLC6A8,THSD1,COBL,SMG6,TCF7L2,ZNF34,ZKSCAN5,FAM155A,VAV1,ZBTB14,EVI5,WIPF2,SSPN" Drug 837_UP (+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "FZD9,MRTFA,APLP1,DGKD,PPFIA3,SLC2A11,N4BP2L1,CFLAR,ST3GAL5,CAMK2B,LRRFIP1,EDRF1,DBT,SPOCK3,RABGAP1L,SLC12A6,DRD1,MBNL2,PLXNC1,KIAA1109,FAM49B,ALDH1L1,GLYR1,TDRKH,LPAR4,NR3C1,GRM8,BTN2A1,GSN,KCNH2,KIF2A,LIG4,AFDN,ADAM22,MYT1,PDE3B,PIK3CD,RETREG1,ZSCAN32,RGS12,RPS6KA2,EMID1,NLGN1,BTBD7,ERC1,ARHGAP26,ZBTB43,TACC1,AHCYL2,REEP1,EVI5" Drug 3790_DN Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADD2,NME5,CDC42BPA,SEMA7A,NRP2,SYNJ1,CACNB2,CBS,CDC42,CLCN4,RAB26,ARMC8,RCHY1,PDE4DIP,RIMS2,EDRF1,DAPK3,C2CD2L,SORBS1,PRELID3A,GPD2,ELOVL5,ICA1,SHISAL1,SCIN,ITGA7,LAMA2,MAPT,MATN3,NEK1,EPN1,STRN3,MAPK8,PRPH,RAB3IL1,RGS4,CSRNP3,SLC1A7,PPP4R3A,LIMS2,ZNF334,LIMCH1,SNCA,TSNAXIP1,KDM4C,IQSEC2,ELOVL4,JMJD6,TIAM1,ZNF24,MAP3K12" Drug 2707_UP Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "NDRG2,KIDINS220,BIN1,DNAH17,MARK4,PTCH2,SGCE,BTRC,CFAP410,CACNA2D1,THSD7A,CREM,CRY2,NCOR2,ABCG1,CTNND1,RIMS2,ANKMY1,FGFR1,FOXF2,GFER,PCDH17,C1QL1,GUCY1A1,HTR2A,MBNL1,NF1,CNOT4,NOVA1,NPTX2,PAH,PAX6,PLCL1,CEP41,VPS13C,PID1,SUSD4,MYH14,ASIC4,LIMCH1,PALLD,NCDN,DNMBP,DNAH7,TGFBR3,HEY1,RUNDC3B,FLRT1,ZBTB38,SLC17A7,KCNAB1" Drug 203_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "NDRG2,BIN1,ASPA,SYNJ2,FUBP1,CACNA1D,INA,SCARB1,NEURL1,STOML1,CRMP1,DLG3,RBM12,SRPK3,ERCC2,BAIAP2,CAP2,PDLIM5,ATP2C1,RUNDC3A,ARHGAP19,SYNPO,AGFG1,ICA1,LMO1,MYT1,NTRK2,CLDN11,PACSIN1,PPM1B,PRKAR1B,TTC13,FERMT1,ABLIM3,SLA,FAM214B,PKNOX2,IGSF9B,SNAP25,SNCA,FAIM2,SPTB,TSPYL2,ST5,PHLDB1,PLCB1,TCF7L2,PARD3,SLC26A10,WNK1,MPPE1" Drug 2847_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,AK2,ALCAM,BIN1,APBB2,MARK4,ATM,CFLAR,KYAT1,MAGI1,LHX2,ZFYVE9,FADS2,NECTIN3,ARHGEF4,TMCC2,EXOG,TSPAN5,KCNMB2,SEMA4D,CAMKK2,ZNF44,GLS,HLF,ELOVL5,IL6ST,KCNH2,KHK,MITF,ADAM22,ZNF862,SLCO1C1,NNAT,PENK,PTHLH,ZSCAN32,ZNF493,SLC25A36,ZNF821,SNCA,WDTC1,SAMSN1,THSD1,SS18,VAMP1,DMXL2,TCF7,AP4E1,ZMYND8,HIRA,WNK1" Drug 2774_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "LTBP4,PPFIA3,MARK4,CADM3,ST3GAL5,SGCE,RCBTB2,ZFYVE9,NMT2,HOMER3,NECTIN3,NCOR2,RIMS3,PARD6A,TMCC2,KBTBD11,CDON,EGFR,PLXNC1,HSD17B14,LRRC23,TUBB4A,GCNT2,RND1,GPM6B,LILRA2,GPER1,HLF,TJAP1,IL6ST,KCNN1,MID1,MX1,SNRK,PTHLH,RAB3IL1,ZDHHC14,RPS6KA2,ARHGEF40,CXXC4,NCDN,PHLDB1,SYN2,TCF7L2,PSD3,SLC35G2,TRO,HIRA,LAT2,EMSY,EPM2A" Drug 2249_DN Ampyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ACTN2,NDRG2,ADCY6,KIDINS220,SEMA6A,CDC42BPA,APLP1,ALDH4A1,CFLAR,ARHGAP33,CRLF1,SLIT2,MICAL2,PDE4DIP,FAM169A,SDC3,PUM1,SEC14L5,RIMS3,CTIF,JAKMIP2,EPB41L2,ZNF589,KIAA1109,CAMSAP1,FAM49B,SRCAP,GLYR1,GRIK5,RASSF8,ADAM22,MYO7A,PC,CDK14,SERPINE2,SLC25A23,RAB3A,KIF13A,SOX2,DOK5,EMC1,STX1A,ARC,WSCD1,TRIO,FAM155A,FLRT2,NSD2,SYNC,WIPF2,TIGD6" Drug 7127_DN Monocrotaline [315-22-0]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ABR,BRAP,APBB2,APLP1,CDK10,CFLAR,B4GALT6,USP6NL,MED24,RCAN1,SUGP2,EGFR,EIF5,STX2,SCML2,FGFR1,CAMSAP1,GNAS,GPD2,DIDO1,GUCY1B1,DIPK1A,MBNL1,MPP2,ODF2,PBX1,KCTD15,TNPO2,PPP3CC,RIPOR1,RAB3A,RAD51D,SUGCT,MCMBP,WLS,ANKRD6,LIMCH1,ZBTB43,PBLD,DIP2A,FAM168A,ARHGEF9,VPS13A,ROBO3,TCF7L2,AHCYL2,HIRA,FAM155A,LMF1,XRCC4,HPS4" Drug 4561_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,ZSCAN18,ADAM23,ST3GAL5,CACNA1D,HAP1,SLC16A4,ENTPD4,SPOCK3,EGFR,EIF4G2,ING4,F5,KIAA1109,FGF1,CAMSAP1,FOXG1,GABRA2,ALDH1L1,RND1,RAB30,GLRB,GPR19,CACFD1,GRM8,ICA1,INPP5B,LYRM9,NOVA2,OMG,P2RX7,PENK,EPN1,BCAS3,GDPD2,ZSCAN32,PTPRN2,RAB3IL1,CCDC40,SEMA6D,SCN2A,SLC6A9,KIF13A,KIF21B,ZSWIM8,EMC1,BEX1,RBM26,LHPP,TEK,CDK20" Drug 4283_UP Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AMPD3,APBB1,ZSCAN18,ALDH4A1,BMPR1B,BAIAP3,CAMK2B,CLDN10,TPP1,STOML1,HOMER3,CTNND2,DAPK3,SGSM2,DMPK,EDN1,HIPK3,ANKFY1,ZNF44,USP19,RUNDC3A,GPR12,GPR17,KIT,LSS,MAPT,MOBP,PLEC,TNPO2,POLR2F,ELOVL2,ZMAT4,RGS4,FOXRED2,ZFP2,SH3BP2,BCAN,DZIP1,SLC12A4,SMARCA4,VAMP1,PLCB1,SZT2,ATP13A2,TK2,TPM3,FLRT2,LAT2,SH3GLB2,MVB12B,DPF3" Drug 5411_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ABHD6,APC,EPB41L5,CDC14B,CDK13,ALDH4A1,CACNB2,KYAT1,SCARB1,ARHGEF2,QKI,NCOR1,EDRF1,ZNF804A,MFAP3L,MED12,CNNM1,CELSR3,MBNL2,SORBS3,EIF5,EPB41L1,FGFR1,CINP,GART,GCNT2,MSL3,IGSF1,LSS,MATK,MIA2,SETD4,PDE3B,RAD52,ATG16L1,RGS12,SLC1A7,ZCCHC24,INKA2,PLCB1,KAZN,CRTC1,PCDHA6,AP4E1,CABIN1,REEP1,GDPD5,HPS4,MVB12B,SMIM8,ZNF248" Drug 6014_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "CDC42BPA,ASPH,ATP6V0A1,BTRC,ADGRG1,CREM,ENTPD4,MED12,TRAPPC9,CDON,EEF1A2,ANKMY1,FGF12,FGFR1,SEMA4D,ERAP1,DISC1,INPP5K,GLYR1,RAB30,GLS,GRM8,HNMT,IL6R,MAP4,ZNF862,NUMA1,PCDH9,PRKAR1B,PTPRE,RALGDS,RGS10,SEC61A2,SBF1,ASAP3,AMBRA1,PEX26,FAM214B,SOX3,ZHX3,LHPP,PLCB1,ASTN2,KAZN,IQCE,TCF7,CABIN1,TRPC1,PLPPR2,KCNAB1,AAAS" Drug 4461_UP fluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADRA1D,OGT,CDC14B,BRINP2,CDK5R2,CBS,INA,CDO1,TPP1,DNAJB5,PDE4DIP,EDRF1,TOX,BRINP1,SRGAP3,DTNA,FOXG1,GABRA2,GAD2,DISC1,ALDH1L1,GDF9,RND1,GRIN1,CACFD1,SOX21,VWA5A,SMAD1,AFDN,MOBP,MYT1,NPPA,PAH,PDE4B,NECAB2,RAD52,RASGRF1,CARF,SLN,RBM34,ZC3H13,CLSTN2,NACAD,DICER1,TMOD1,LILRA4,BEST1,SYNC,ZNF225,SLC17A7,KCNAB1" Drug 5386_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,ARID1A,KIAA1324,C1QTNF1,MRTFA,APOC1,APP,CAMK2G,CLTB,FHL5,ABI3BP,ARHGEF4,RIMS2,RIMS3,PHYHIP,CTIF,TMCC2,ATN1,EDIL3,EFNB3,CEND1,FHL1,TMEM8B,SRCAP,CNTRL,NR3C1,C2orf72,KCNQ3,MAN2A2,AFF1,ADAM22,MYO7A,NF1,NOS1,PACSIN1,MAPK7,PTHLH,NKAIN1,C1orf54,FAIM2,RBM34,ZHX3,SAMSN1,MAPK8IP3,POPDC3,TAC3,DMXL2,HIF3A,THRA,DNALI1,PAK5" Drug 500_DN copper(II) sulfate pentahydrate; Down 200; 100uM; ssMCF7; HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "OGT,BCAS1,ATP6V0A1,RGS11,NEURL1,CHRM4,DDX46,DRP2,DTNA,MBNL2,PLEKHA1,PLEKHO1,F3,FGFR1,BAIAP2,FLNC,POMT1,RUNDC3A,GPER1,GRIK5,GRM1,PTPRT,GSN,SOX21,HMX1,MARK1,MBD1,MYO7A,FXYD6,NF1,NPPA,RETREG2,MBOAT7,PACSIN1,ARHGEF10L,EMID1,RASA3,PEX26,SNCA,KDM4B,LMO3,SSTR2,ELOVL4,STX1A,EXOC7,AHCYL2,TF,CRB1,GPR161,PARD3,PLPPR2" Drug 2277_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADORA3,ATP1A3,NRP2,BAIAP3,CBFA2T2,GPR37L1,TAOK2,EDRF1,CTIF,MAGI2,SHANK1,DRP2,EDN3,VPS13B,DCTN2,DLL3,OGA,ATP8A2,C1QL1,GPER1,GRK4,STMN2,ITGA7,KCNJ4,KCNJ5,KIFC3,MSI1,MSR1,MYT1,NDUFA5,SLCO1C1,PFKFB2,LRRN3,PTCH1,RPS6KA2,ASAP3,SLC1A2,SLC2A5,SLC6A9,SOX10,NPAS3,ABCC8,EXOC7,ADGRL3,WSCD1,DMXL2,SZT2,PSD3,HEY2,UCHL1,PRDM2" Drug 4720_UP Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "RALGAPA1,NME5,LTBP4,ATM,HAP1,CAMK2G,RUNX1T1,KRIT1,CRLF1,QKI,ENTPD4,CRMP1,GREB1,HDAC9,MAML1,GIT2,SMG7,EFNB3,EN2,NCALD,CAMSAP1,FOXG1,GALC,C1QL1,GLYR1,CACFD1,IL6ST,KCNH2,MAP2,ADAM22,NTRK2,SERPINI1,PLCD1,MTRF1L,PMS2,LRRN3,PTHLH,SFPQ,SH3BP2,AMBRA1,FBXO11,WDTC1,ZC3H13,AJAP1,SYN2,TBL1X,PCDHGA10,OBSL1,PCDHA6,ZMYND8,HIRA" Drug 3869_UP Chlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASIC1,ADRA1D,APAF1,CDC14B,ASCL1,ADAM23,PROM1,GYG2,CACNA2D1,NEURL1,CHRNA4,TAOK2,STOML1,CNTN1,SEC14L5,DYRK1A,ST8SIA3,FGF13,FGFR1,CAMSAP1,AGAP2,B3GAT1,NEU3,GLI2,PCLO,GRIK5,GRM2,ITIH2,KPNA5,KITLG,MID1,ADAM22,NNAT,PFKFB2,ABCB1,STRN3,VPS13C,ZSCAN32,RAB3IL1,RGS12,ZFP2,ST6GAL1,SNCA,SOX2,MAPK8IP3,PHLDB1,TBCEL,DOCK9,TMOD1,TMPO,LAT2" Drug 2374_DN Diphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ALK,AMT,ARNTL,ARHGEF7,CD86,CDH10,QKI,IQCK,FEZ1,TRAPPC9,SORBS3,COQ7,VPS26C,WAC,ZNF589,FHL1,ALDH1L1,AHDC1,TXNL4A,SPIN1,GLS,MSL3,GOLGB1,LILRA2,GPR22,KIF2A,LSS,NFYA,OCRL,OGG1,NLE1,ST8SIA5,SAMD9,TCP11L1,TMEM156,RASA3,FAM102A,FNDC3A,KDM4B,ZCCHC24,ZBTB43,DDN,MAPK8IP3,ATP11A,SLC44A1,RBFOX2,ZKSCAN5,PLPPR2,NSD2,MPPE1,NLRP3" Drug 4417_UP Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "SYN3,TKTL1,AGT,APAF1,CDC14B,SEMA4G,ALDH7A1,N4BP2L1,CACNA1D,CALB2,CAMK2B,CDH2,STOML1,CLTB,WHRN,CREM,ARMCX2,ATN1,TNK2,ELN,C3orf18,KCNMB2,NRN1,FGFR1,FHL1,DISC1,RND1,GPD2,PTGDR2,VWA5A,MEF2C,BCO1,PACSIN1,PKN2,SAMD9,TTLL7,TMEM206,ST6GAL1,LIMS2,SNCA,SOX2,ZCCHC24,SOX10,NPAS3,INKA2,PHLDB1,SYNE1,HEY2,XRCC4,ZNF711,DNALI1" Drug 7491_DN CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "APAF1,ARRB1,SYNJ2,CAMK2B,ADGRG1,CHRNA4,IQCK,VCAN,RIMS3,BRINP1,DTNA,MBNL2,TENM1,TESK2,FGFR1,SCARA3,GALC,ZNF276,GPM6B,GPR17,SCRG1,ICA1,SHISAL1,TJAP1,IL6ST,IL11RA,KCND3,KCNN1,GIT1,PALM,EPN1,PTN,RAD52,SH3TC2,MYH14,SH3BP2,MYH15,SP4,SPTB,ASTN2,SEMA4A,CRTC1,TRPC1,ZMYND8,NT5M,HPS4,PCBP4,EPM2A,HRASLS,PHTF2,ACTR3B" Drug 6141_DN Meropenem [96036-03-2]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ABHD6,MTUS1,PLA2G6,ALAD,APAF1,ARRB1,SLC4A4,N4BP2L1,SLC25A14,ARHGAP33,FOXN3,SOCS6,RAB28,ZFYVE9,CTNND1,ZFYVE16,RUSC2,SMG7,FCF1,FAM13A,SCML2,ST3GAL6,PCYOX1,ANKFY1,OGA,ERAP1,SEPT9,GART,ALDH1L1,SRCAP,TXNL4A,GLYR1,JAK2,MAP4,ZNF862,NF1,SLC11A2,SETD4,OCRL,RAD52,SH3BP2,AMBRA1,FAM214B,SNCA,TSPYL2,CAMSAP2,PDLIM2,PARD3,HIRA,XRCC4,NT5M" Drug 6571_DN Prostaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "C1QTNF3,APBB2,APOC1,PPFIA3,CFAP410,CCNT1,CDC42,CHN2,ZFYVE9,NRG2,SPOCK2,RHOBTB1,DTNA,ING4,KAT8,FGFR1,BAIAP2,FLT1,GCNT2,AHDC1,COPS8,GPM6B,KCND3,KHK,MIA2,MN1,LYRM9,SLC11A2,PIK3CD,SAMD9,PTPRH,PTX3,SH3TC2,RGS7,RNASEL,RPS6KA2,MAPK12,SH3BP2,ASAP3,CNKSR2,LIMS2,KDM4D,SHANK2,DOP1A,CLUAP1,PBLD,SYT11,TNS1,RPRM,NAV3,KCNAB1" Drug 7377_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "C1QTNF1,APBB2,CDK10,SYNJ2,MYRF,MAP7,RAB28,NIPBL,ENTPD4,KIAA0513,B3GAT3,SGSM2,DLG3,CDON,SORBS3,EN2,EPB41L1,F3,F8,POMT1,GAD1,B4GALNT1,DISC1,GBX2,CRCP,SYNPO,MYO9A,ZNF862,NFIX,NPR2,SLC11A2,PCDH9,SERPINI1,POLG,FSD1,PTN,PEX5,RIPOR1,RPS6KA2,FAM102A,SH3GL2,FAM214B,LIMCH1,ARHGAP26,SYNE1,CABIN1,VGF,ZBTB14,MAP3K12,NT5M,WIPF2" Drug 4453_UP clozapine; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,ACTN2,PTCH2,ATP2B2,CADM3,CALB2,RUNX1T1,SH2B1,CSF1,EDRF1,TOX,BRINP1,RABGAP1L,ARNT2,TRAPPC9,ATN1,DSCAM,EDN1,CELSR3,ATP8A1,GAD2,ADAM28,GNG4,GRIA4,GRM8,HPCA,KCNH2,KHK,MGAT3,MOBP,MSI1,DDX25,NCAM1,NEUROD1,CAMKV,PPP2R2B,TCP11L1,SALL1,SCNN1D,SH3BP2,PPM1E,FRMPD1,CNKSR2,KANSL3,SLC11A1,FAIM2,KIF21B,ADGRL3,THRA,BHLHB9,PDIA2" Drug 6146_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "CDC42BPA,PKP4,APC,NCOA1,ATP6V0A1,CFLAR,SCAPER,CFAP410,CAPN3,KRIT1,ZFYVE9,CLCN4,SLC4A7,HINFP,SLITRK5,RABGAP1L,NR1D2,DTNA,F3,ST3GAL6,INPP5K,USP19,AGBL5,ICA1,IL6ST,LSS,MAP4,MIA2,SLC11A2,PLCB2,STRN3,PRKAB2,RAD52,ZCWPW1,ZNF493,RNASEL,ZNF821,SH3BP2,NUBPL,PPP4R3A,KDM4C,SS18,TCF7L2,THBS4,PARD3,ZKSCAN5,FLRT2,XRCC4,EMSY,KCNAB1,UBE3B" Drug 3093_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AP1B1,MTUS1,PKP4,ASPH,BCL7A,CFLAR,LDLRAD4,SLC16A4,ARHGEF1,CLGN,CHM,B4GALT6,PLAA,NIPBL,CSF1,HIPK3,MBNL2,BSCL2,EPS8,EZH1,FECH,KIAA1109,PDLIM5,OGA,GNAS,PRRC2B,GPR19,GPR22,DIDO1,MKLN1,ZNF862,NF1,NFYA,SNRK,PTPRO,CCDC25,SEC14L1,FBXO11,SLC2A5,SMARCC2,DBNDD2,CDK19,RGL1,VAMP1,TCF4,TCF7L2,TNNT1,NPL,TPM3,PARP11,PHTF2" Drug 7205_UP Sulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ACTN1,NDRG2,FZD9,NME5,AK2,APBA2,CDK10,ARHGDIG,ATM,NRP2,CACNB4,CAMK2G,USP2,CLGN,B4GALT6,AKAP7,RCHY1,BAG4,NCOR2,RGS6,ST3GAL6,DLL3,OGA,GATM,RUNDC3A,PRUNE2,GRIK5,GRM8,ITPKB,LIG4,MDM4,NF1,CDK14,SLC25A23,PRPH,RGS12,GSTCD,SLC1A7,PEX26,EPN2,PHLDB1,SEMA4A,TRIM2,PCDHA5,FAM155A,ZNF711,ZNF24,SYNC,WNK1,PRDM2,SEMA3B" Drug 3208_DN Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "APBB2,CDC14B,KRIT1,B4GALT6,RAB28,ZFYVE9,HOMER3,CSNK1E,DBT,DNAJC6,PARD6A,RABGAP1L,ING4,ENO2,FGFR1,BAIAP2,SRCAP,GLS,GNG4,FERMT2,GRB10,BTN2A1,HNMT,HSF2,KIF5C,MIA2,NAP1L2,NASP,NEK1,PCDH9,PDE3B,VPS13C,GON4L,NKAIN1,RAP1GDS1,NEK11,TRAPPC13,ITSN1,SLC20A2,COA1,TSPYL2,TROVE2,POGZ,AHCYL2,TMPO,HIRA,UBTF,LMF1,XRCC4,HPS4,PHTF2" Drug 2063_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "MRTFA,PKP4,CASK,CDK13,SCAPER,RAB29,MYRF,BTRC,KRIT1,CLCN3,HOMER3,LYPD1,RABGAP1L,DPH1,FCF1,COQ7,FGF1,TRMO,SORBS1,GPR19,IL6ST,MAPT,MEF2C,SCAMP5,ADAM22,NDUFA5,NFYA,NUMA1,MAPK8,PTPRE,ZDHHC14,RGS4,TTLL7,KIRREL1,TRA2B,PPP1R9A,PPP4R3A,IFT122,CAND2,IQSEC2,CDK19,SAMSN1,EXOC7,TBCEL,EHBP1,TCF4,KIAA0930,UGT8,ZNF189,MAP3K12,KAT6A" Drug 7330_UP Gibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "AK2,APAF1,KIF1A,CFLAR,SCAPER,CACNA1D,USP2,CHI3L2,CHM,B4GALT6,HOMER3,CSF1,FAM169A,TBC1D5,BRINP1,JAKMIP2,MFAP3L,RABGAP1L,DUSP9,EFNA3,RRAGB,EZH1,C1orf61,FAM49B,PRELID3A,ZNF44,RND1,TXNL4A,CACFD1,ADAM11,NF1,CNOT4,PDE3B,MTRF1L,PPP5C,FAM120C,RIPOR1,RAD52,GTDC1,KCTD17,SHANK2,ZCCHC24,EMC1,ERC1,SPTAN1,MAPK8IP3,PCDHGB6,R3HDM1,TFIP11,SYNC,SSPN" Drug 5819_UP Trifluridine [70-00-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ADGRF5,ASCL1,SLC4A4,CFLAR,CFAP410,CACNB2,CAMK2B,CHRNA4,LHX2,ABCG2,PCYT1B,CREB5,ABCG1,PDE4DIP,DZIP3,GIT2,DTNA,FEM1B,EFNA3,MRNIP,TUBD1,STX2,SCML2,FLT1,ERGIC3,GLRB,SPACA9,GRIK5,KIF5C,NF1,PCDH9,PIK3R1,RAB3IL1,SLC6A15,MYH14,TMEM206,ASAP3,FNDC3A,BCAN,TMCC1,KIF21B,ZBTB43,PLCB1,SZT2,VGF,KCNK12,PARP6,MPPE1,PLSCR4,HRASLS,RNF170" Drug 4089_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "DPF1,ACTN2,ANK1,ARSE,PDE8B,CADM3,N4BP2L1,CAMK2B,NRXN3,AKAP6,ABCG1,CSF1R,SPOCK2,C2CD2L,EXOG,DRP2,ATN1,RASGRP2,IGSF6,AGAP2,DISC1,GNAO1,GPR17,TPPP,GRIK1,GRM8,PADI2,KCND3,KCNJ5,MAG,MAN2A2,AFDN,ADAM22,NF1,NTRK2,PDE2A,PFKFB4,PACSIN1,C19orf57,MAPK10,SEMA6D,ZNF334,RBM26,DDN,ATP10B,SYT5,SPX,TPM3,TRH,KCNK12,KCNAB1" Drug 5425_DN Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "SEMA6A,ARRB1,CFLAR,BTRC,CFAP410,TPP1,QKI,CREM,CNTNAP2,EDRF1,SMG7,FCF1,OPTN,EIF4G2,VPS13B,EPB41L1,FGFR1,PRKAG2,FHL1,INPP5K,GLYR1,RAB30,HNMT,IL6ST,JAK2,KCNJ3,KPNA5,LSS,KITLG,NF1,NFYA,NTRK2,OXTR,STRN3,MED1,PPP2R5C,ZSCAN32,CEP97,RGS10,CLIP1,BTBD7,EMC1,INKA2,MAPK8IP3,PLCB1,EXOC7,TRIM2,RPGRIP1L,CABIN1,KCNK12,EMSY" Drug 2458_UP Cefotiam hydrochloride; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "NDRG3,CDC42BPA,ALDH4A1,N4BP2L1,ADGRB1,SPAG9,SLC16A4,CHM,COL9A3,NCOR2,DBT,SMG7,RCAN1,EIF1,F5,KAT8,OLFM1,PCYOX1,CAMKK2,GPR153,GABRA4,ZNF44,ZMYND11,GART,MYOZ2,ALDH1L1,SOX21,ATXN2L,HSF2,ITIH2,KCND3,NPPA,OCRL,PLCD1,MAPK8,ACSS3,RPH3A,HECW1,SS18,NXT2,MAPK8IP3,SYT1,TAC3,IQCE,ZEB1,RPGRIP1L,ATP13A2,TNS1,ZMYND8,UBTF,VGF" Drug 5011_UP Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "KIAA1324,C1QTNF1,SPARCL1,MRTFA,BIN1,CNTNAP1,APBA2,CHRD,GYG2,CAMK2B,NEURL1,CNTN1,NCOR2,RIMS3,SMG7,SPOCK3,ATN1,ST8SIA3,HIPK3,MBNL2,LRRC23,STX2,ERCC2,CORO2B,DLC1,OLFM1,FGFR3,ERAP1,GLS,GPM6A,SPACA9,KCND3,KCNH2,KCNMA1,KIF5C,NF1,NKAIN1,ZNF493,SYNDIG1,SBF1,ASAP3,PKNOX2,LIMCH1,HECW1,CDK19,ST5,PLCB1,VIPR2,EVI5,PLSCR4,DPF3" Drug 3144_UP Deptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ALK,ARHGDIG,CDK5R1,CACNA1I,THSD7A,NEURL1,TAOK2,CREB5,NCOR2,TM9SF4,MFAP3L,DNM1,CDON,DSCAM,DTNB,CELSR3,EVL,GABRA2,GAD1,GUCY1A1,PADI2,HTR2A,KCND3,KCNK1,PTOV1,NCAM1,NRGN,NTRK2,NUCB1,PLCB2,PLPPR1,RIPOR1,RASGRF1,FAM102A,SMTN,SLN,SMARCA4,SNCA,PALLD,SPTAN1,SPTB,MAPK8IP3,MTCL1,OBSL1,THRA,TJP1,SF1,MKRN3,SPHK2,GDPD5,SLC17A7" Drug 2245_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ASPHD1,SYN3,MRTFA,APBB2,ATP1A2,CFLAR,SYNJ2,BAIAP3,CAMK2B,USP2,EPS15L1,SULT4A1,CNTN1,FAM149A,SLC4A7,CNTNAP2,RASSF2,RABGAP1L,TRAPPC9,DRD1,MBNL2,ELAVL3,APC2,PTK2B,FGFR1,C1orf61,OGA,LYVE1,RND1,MSL3,NR3C1,GRM1,GRM7,IL6ST,MEF2C,MOBP,NDUFA5,POU3F4,LRRN3,MAPK7,DOCK10,ZC3H13,MAPK8IP3,JMJD6,VAMP1,PCDHA5,AP4E1,R3HDM1,WNK1,ITM2C,DPF3" Drug 5298_UP Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.37E-04 1.00E+00 1.38E-03 1.57E-02 51 196 "ALCAM,APOC1,CDK10,ASPH,ST3GAL5,CRLF1,CACNA2D2,TAOK2,VAX2,HOMER3,NCOR1,VCAN,PDE4DIP,GIT2,RABGAP1L,CNNM1,EFNA3,SORBS3,MRNIP,EPB41L1,STX2,BAIAP2,SEMA4D,FYN,GLS,CNTRL,DIDO1,KCNH2,KIF5C,MAP4,MBD1,NEK1,NRGN,PLCD1,LRP12,RAB3A,GTDC1,RPS6KA2,FNDC3A,KDM4C,THSD1,RGL1,STX1A,ATP11A,TRIM2,PSD3,HEY1,RUNDC3B,LMF1,GDPD5,MPPE1" Drug CID000024411 oxovanadium Stitch 1.41E-04 1.00E+00 1.41E-03 1.61E-02 35 120 "KIDINS220,MYH7B,PDXK,ARNTL,ATP1A1,ATP1A3,ATP6V0A1,CANX,CDO1,MYL6B,VCAN,ARHGAP32,DLG4,DMD,CDON,SLC25A18,RCAN2,F8,ATP6V1H,ITIH2,MYBPC1,MYH3,MYH6,MYH7,MYL3,ABCB1,RNH1,SHC4,ARC,TNNT1,TSN,TTPA,ZIC3,DPYSL5,PMEPA1" Drug CID000011313 Congo red Stitch 1.41E-04 1.00E+00 1.41E-03 1.61E-02 35 120 "APAF1,APLP1,APOC2,APP,CDK13,CHGA,GAL3ST1,NTM,DYNC1I1,ATN1,GNE,EN2,ENO2,PPP1R1B,GFAP,PPARGC1A,TCERG1,PACSIN2,KITLG,MXI1,OGG1,PAH,PIK3C2A,PACSIN1,FSD1,PTX3,QDPR,PID1,WLS,ATXN7,FOXRED1,SLC1A3,UBC,HPS4,JPH3" Drug CID000019390 AC1L2E0P Stitch 1.41E-04 1.00E+00 1.42E-03 1.61E-02 73 307 "C1QTNF3,SPOP,PHF12,APP,NCOA1,DYNLL1,RIPK1,CALM1,RUNX1T1,CCNH,SCARB1,COPB2,CHGA,ZFYVE9,CLU,NCOR1,NCOR2,HDAC9,MED24,GSDME,MED12,ERBB2,GMPR2,KAT8,FGR,FHL1,FOXM1,PPARGC1A,LYVE1,BRD8,RAB40B,GPD1,GPD2,NR3C1,KAT7,DDX19B,HPSE2,HMX1,HNF4G,HP,HPR,LMO2,MEST,AFF1,AFDN,PIK3R1,PPARA,MED1,MAPK9,MAPK10,PROX1,RBBP8,RGS3,GSTCD,RORB,ELP2,RXRA,RXRG,SAFB,SMARCA4,IFT122,TRERF1,MMS19,NSD1,THRA,CBX5,KAT6B,TMEFF2,ZBTB16,RNF103,SCG2,KAT6A,AP3B2" Drug CID000448615 AC1L9M5J Stitch 1.43E-04 1.00E+00 1.43E-03 1.63E-02 56 221 "ADAR,SLC12A5,APP,SLC4A4,CACNA1E,CDH2,TPP1,SDC3,PUM1,NTM,ELAVL3,FGF1,FGFR1,NSG1,GABRB3,GBX2,GFAP,GRIA1,GRIA2,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,NKD1,MAP2,MAPT,MARK1,ADAM11,MEIS1,MEIS2,GIT1,NEFM,NEFH,NTRK2,MAPK3,RELN,RPS6KA2,RXRA,RXRG,S100B,SLC1A2,SOX3,SEPT3,SYP,TACR1,TK2,NTSR2,KCNE5,WNT7A,NDRG4,MAP3K12,LRP8,GJC2,VANGL2" Drug 584_UP dimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 1.44E-04 1.00E+00 1.44E-03 1.64E-02 46 172 "PPFIA4,ARRB2,CADM3,BMP7,CREM,ECE2,RASSF2,ABCC9,SIDT2,EFNA3,FAM13A,MBNL2,ENO2,FGFR1,RUNDC3A,ITIH2,KCNK1,KCNN1,MXI1,NTRK3,PC,PFKFB3,PFKFB4,EPN1,PRKAR1B,MAPK3,MAPK8,MASP1,PTX3,RAB3A,SLC25A36,SCG5,ITSN1,ASAP3,SLC9A5,KDM4B,KDM3A,SPART,JMJD6,MCF2L,CBX5,OSBP2,WIPF1,ZNF189,VPS35L,MVB12B" Drug CID000008974 2-chloroadenosine Stitch 1.46E-04 1.00E+00 1.46E-03 1.66E-02 31 102 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,ALDH7A1,BSN,B4GALT6,PLCXD3,SNPH,SLC29A4,DPP6,AHCYL1,GPR162,PLCD4,TNFAIP8L3,KLHL23,MAP4,CCDC80,PDCD2,PLCB2,PLCD1,RNH1,SST,PLCB1,AHCYL2" Drug ctd:D014501 Uranium CTD 1.46E-04 1.00E+00 1.46E-03 1.66E-02 71 297 "NDRG2,ADAR,SLC44A5,APBB1,APC,APP,ASCL1,NAE1,CALB1,CAMK2D,CANX,CBFA2T2,MFSD4A,CP,SDC3,APPL1,PUM1,TOMM20,SNAP91,CHRDL1,PDCD6IP,DTNA,VPS13B,SRRM1,SEC24B,EVL,NSG2,IQGAP2,GLUL,KDM2B,STMN2,HMGB1,SMAP1,KIT,LAMP2,STMN1,NCOA7,NAP1L1,SLC11A2,PDE1A,PFKFB4,PIK3R1,C11orf49,CRLS1,PTK2,PLEKHB2,RDX,RPL15,BAALC,RXRA,RMI1,SCN2B,SCP2,SLC8A1,COA1,KDM4B,SPP1,KIF1B,ABCC8,DNAJC9,KAZN,TF,TNFRSF1B,NEIL2,VSNL1,NDRG4,REEP1,DPYSL5,CSDE1,EVI5,TUBA1A" Drug 985_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.47E-04 1.00E+00 1.47E-03 1.67E-02 47 177 "ADD3,CDC42BPA,BARD1,CA12,CDC27,QKI,SLC4A7,TBC1D5,NR1D2,RASGRP1,EGR3,EIF4G1,PLEKHA1,DLC1,CAP2,PCYOX1,CAMKK2,STAG2,SPIN1,KTN1,MBP,MYO6,PBX1,PIK3R1,MED1,PKN2,TMEM260,PLEKHB2,RBBP6,SLC25A36,ATXN1,ZNF430,SMARCA4,SON,MYCBP2,SRPK2,TROVE2,PRRC2C,KAZN,TBL1X,WASHC4,DICER1,KAT6B,USP1,ZNF24,ZBTB38,SNX27" Drug CID000001355 m-chlorophenylpiperazine Stitch 1.49E-04 1.00E+00 1.49E-03 1.69E-02 21 59 "ABR,BMPR1B,DPH1,AASS,STX2,EPS8,F3,ZMYND10,HTR2A,HTR5A,MBD1,NF1,NUCB1,NUCB2,PDYN,PENK,S100B,SOX10,TROVE2,ZEB1,NSD1" Drug ctd:D000069470 Venlafaxine Hydrochloride CTD 1.49E-04 1.00E+00 1.49E-03 1.69E-02 21 59 "LARGE1,EFNA2,EFNA3,EFNB3,NR3C1,BRINP3,KCNH2,KCNJ3,KCNJ5,NASP,ABCB1,SERPINI1,PLXNB1,MAPK3,ROBO2,SALL1,PREX2,ARC,SYP,SYT4,TCF12" Drug CID000001564 2-hydroxysaclofen Stitch 1.49E-04 1.00E+00 1.49E-03 1.69E-02 21 59 "ABAT,ADORA1,ADRA1B,BCS1L,GABBR1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GLRB,GRIK1,GRIN2C,GRIN2D,KCNJ3,OPRL1,PIK3R1,SSTR2,TAC3,MLST8" Drug CID000002663 celiprolol Stitch 1.50E-04 1.00E+00 1.50E-03 1.70E-02 18 47 "ADRB2,CACNA2D1,TBPL1,CYBB,EDN1,MATK,NPPA,ABCB1,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,SLC12A4,PORCN,NETO1" Drug 1663_DN "ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.50E-04 1.00E+00 1.50E-03 1.71E-02 48 182 "AK2,LTBP4,PPFIA1,BCL2L2,SYNJ2,CA12,EPS15L1,MICAL2,GREB1,TBC1D5,RHOBTB1,DNM1,RASGRP1,EGR3,ENO2,EFCAB2,GPR153,INPP5K,SRCAP,CNTRL,JAK2,KCNF1,MAP4,MAPT,NF1,NPR2,PDE3B,PLEC,SMOX,ELOVL2,RAB3A,RALGDS,RBBP8,RET,SGK1,FAM102A,EPN2,DHX30,WDTC1,EMC1,ZBTB43,TROVE2,SEMA4A,WWC1,ZBTB14,WNK1,LRP8,SEMA3B" Drug 1755_UP Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.50E-04 1.00E+00 1.50E-03 1.71E-02 48 182 "ADORA1,ARRB2,CADM3,CFLAR,CBR1,CD86,CD38,MAP4K4,CNTFR,AKAP7,CREM,SH2B1,AATK,SIPA1L1,DOCK4,ARHGAP32,BAIAP2,NSG1,CACFD1,GRM1,PACSIN2,KIFC3,LAMP2,NACA,OLR1,PALM,PDE4B,SMOX,PACSIN1,QDPR,MRPS18A,SATB1,FUZ,FNBP1,BEX1,SAMSN1,THSD1,CEP68,MLC1,PLCB1,TAC3,THBS4,TPM4,SSBP2,FLRT2,NPDC1,MPPE1,ST7" Drug CID000002474 bupivacaine Stitch 1.51E-04 1.00E+00 1.51E-03 1.72E-02 36 125 "ASIC1,TKTL1,NR0B1,AQP4,ARHGDIG,ASIC3,DMD,OGA,MSTN,GK,HP,HPR,ITGA7,KCND3,KCNH2,KCNJ3,KCNJ5,KCNK1,KCNK2,KCNK3,KCNQ2,MYBPC1,OPRL1,KCNK10,PRKCB,PRKCG,PKN2,PRKCZ,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,UBTF,PDIA2" Drug 5438_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.53E-04 1.00E+00 1.53E-03 1.74E-02 49 187 "ACTN2,ADORA1,TRMT9B,ASPA,SCAPER,EPS15L1,CPS1,PLCH2,SNPH,MFAP3L,PLPPR4,DMPK,SLC12A6,EGFR,ELN,C3orf18,MTSS1L,ETV1,FOXG1,TPPP3,TBR1,ERAP1,GNG3,MAP4,ADAM22,NF1,NOVA2,MTRF1L,PLXNB1,PTAFR,PTCH1,ELOVL2,PTPRN2,RAD52,C1orf54,RPS6KA2,SEMA6D,ATXN1,SLC2A5,SNCA,DOK5,HECW1,MTCL1,TRIM2,SZT2,R3HDM1,FAM155A,DNAJC12,NUP214" Drug 4323_DN Dicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.53E-04 1.00E+00 1.53E-03 1.74E-02 49 187 "ANK3,APC,ASPH,ATM,STX16,CFLAR,BTRC,CHM,CREB5,CRMP1,PDE4DIP,DBT,HP1BP3,SMG7,EDIL3,HIPK3,EGFR,MBNL2,STX2,CGREF1,FERMT2,SPACA9,GSTM5,RASSF8,ATXN2L,AGFG1,TJAP1,IL6ST,MAP4,NFYA,CNOT4,NUMA1,PDE1C,STRN3,PRKAB2,C1orf54,KIRREL1,CCDC88A,PEG10,TBL1X,EHBP1,PSD3,TMPO,TRIO,ZNF711,WNK1,PRDM2,EVI5,KAT6A" Drug 1614_DN Hycanthone [3105-97-3]; Down 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.53E-04 1.00E+00 1.53E-03 1.74E-02 49 187 "OSBPL1A,ALCAM,CDC42BPA,LRBA,FOXN3,NIPBL,SLC4A7,CSF1,MICAL2,CTH,TBC1D5,ELMO1,RABGAP1L,DTNA,LPAR6,VPS13B,FYN,PRRC2B,KCNN2,MITF,MX1,MYO5A,NACA,NEFH,NF1,CDK14,FTO,MBOAT7,PTAFR,PTK2,RAB3IL1,GTDC1,MRPS18A,RPS6KA2,ATXN1,SLC2A5,SLC11A1,KDM4C,ERC1,UNC5B,ATP10B,RGL1,SUPT5H,VPS13A,EHBP1,TCF4,TCF7L2,PIK3R5,PDSS2" Drug 4364_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.53E-04 1.00E+00 1.53E-03 1.74E-02 49 187 "SYN3,NDRG2,BIN1,APBA2,N4BP2L1,CACNB4,CCKBR,CRMP1,VCAN,NOS1AP,CTIF,SV2A,RCAN1,ELN,TUBB4A,CORO2B,FYN,GAD1,DISC1,GRIK2,IL1RAPL1,ATXN2L,KLF12,IRF8,KCNH2,KCNJ5,KCNMA1,MOBP,NTRK3,PGAM2,PIK3CD,PLTP,PDZRN4,CNKSR2,IZUMO4,ATP10B,SSTR1,ZC4H2,STX1A,WSCD1,ZEB1,DNAH7,TK2,R3HDM1,HIRA,XRCC4,EMSY,STMN4,JPH3" Drug 7511_DN daunorubicin HCl; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.53E-04 1.00E+00 1.53E-03 1.74E-02 49 187 "NDRG3,BCAR3,MAP4K3,APBB2,ASPH,BLM,MAP7,LHX2,QKI,FAM169A,DBT,E2F5,PHC2,EGFR,DCTN4,VPS13B,SPIN1,PSRC1,GPER1,HAS2,ARHGAP19,KLC1,NAP1L3,NF1,NFYA,PDE4A,PLEC,PKN2,VPS13C,PTHLH,PEX2,SH3TC2,ZNF365,PDZD2,TNIK,CLUAP1,RBM26,RAP1GAP2,TAB2,NEK4,CAMSAP2,TCF7L2,TMEM121,PARD3,TPD52,TRIO,TRIM9,NDRG4,MVB12B" Drug CID000005123 willardine Stitch 1.54E-04 1.00E+00 1.54E-03 1.75E-02 14 32 "FOLH1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRM3,KCNA2,NBL1,ADHFE1,ABCC8" Drug CID000102191 V0509 Stitch 1.55E-04 1.00E+00 1.54E-03 1.75E-02 66 272 "ADCY2,ADCY5,ADCY6,ADCY8,BRAP,APAF1,ATP2A2,SLC2A11,DST,CCK,RAB3C,CNR1,CS,HDAC4,DYNC1I1,ATN1,RCAN1,EN2,PPP1R1B,FOXG1,FOXM1,AFF2,SORBS1,CAMKK2,PNMA2,GCK,GFAP,PPARGC1A,GK,TCERG1,RAPGEF1,GRIA1,GRM5,PTPN5,PACSIN2,HNRNPK,HP,HPR,IGF1,KCNJ4,MBP,NPY,NOVA2,OGG1,PENK,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PACSIN1,PRKCB,PYGM,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SLC2A5,SLC6A8,BEX1,SST,EXOC7,DICER1,SMUG1,FXR1,JPH3" Drug CID000122028 "PD 81,723" Stitch 1.55E-04 1.00E+00 1.54E-03 1.75E-02 12 25 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,KCNJ3,KCNJ5,ARHGAP9" Drug CID005311098 Ns102 Stitch 1.55E-04 1.00E+00 1.54E-03 1.75E-02 12 25 "DLG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3,MAPK8,MAPK9,MAPK10" Drug 3391_UP Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "DPF1,ASIC1,KIAA1324,ALCAM,ANK1,CACNA1I,CACNA2D1,CAMK2B,TAOK2,LHX2,EPS15L1,WHRN,SDC3,RASSF2,NTM,TMCC2,EGR3,RASL12,NRN1,PTK2B,TUBB4A,GAP43,DISC1,GPR162,C1QL1,GPER1,JAK2,ADAM22,TAGLN3,MX1,MYT1,NPTX2,MAPK7,ZDHHC14,TRIM68,RET,SYNDIG1,SLC4A3,KDM4B,ZC3H13,BEX1,ARHGAP26,ROBO3,HEY2,TMOD1,UGT8,VLDLR,DNALI1,KCNAB1,AP3B2" Drug 2271_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ASIC1,NDRG2,LTBP4,AMPD3,BIN1,APBB2,ARRB1,CA12,KRIT1,CCNT1,ARHGEF2,MAGI1,PLEKHB1,LHX2,ABI3BP,MICAL2,GREB1,EDNRA,SRCAP,RAB30,GNG4,SPACA9,GRIK5,IGSF1,INPP5B,ITPKB,JAK2,KCNH2,KCNJ3,KITLG,MMP16,ZNF862,NOS1,CDK18,PLCD1,ZNF821,SUPT20H,SH3BP2,ZNF365,KDM4B,ZCCHC24,KDM4C,TROVE2,PHLDB1,ATP11A,KIAA0930,TNS2,THRA,UBTF,ST7" Drug 2846_UP Trimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ALCAM,ALK,BEGAIN,APOC1,ATM,CFLAR,BMP7,BTRC,ARHGAP33,MAGI1,CHM,PDE4DIP,NOS1AP,EXOG,SIDT2,ERCC2,VPS26C,FAM49B,GAB1,GAD2,SLC2A6,ICA1,IL6ST,INPP5B,LMO2,BCO1,SERPINE2,PLCD1,MBOAT7,MINDY2,PRKAR1B,RGS12,SLC25A36,SMTN,ZBTB43,ARHGEF9,ATP11A,PSD3,TMEM121,TGFBR3,TMOD1,CDK20,TRIO,ZMYND8,HIRA,PDIA2,LMF1,SLC30A3,EMSY,GDPD5" Drug 6659_DN Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ARID1A,KIDINS220,PLA2G6,KCNAB2,APOC1,CDK13,CFLAR,FOXN3,SOCS6,NMT2,DNAJB5,ABCG1,PDE4DIP,DZIP3,KIAA0513,SMG7,TOM1,EDIL3,HSD17B14,ETV1,ZNF589,FER,KIAA1109,DENND2A,ERAP1,TMEM8B,INPP5K,GART,USP19,NUDT21,IL6ST,VWA5A,LSS,MEF2C,PAK3,PIK3R1,CNNM2,WDR25,PID1,RALGDS,SH3TC2,RPS6KA2,CCDC88A,SPART,TROVE2,ARHGEF12,TRIO,XRCC4,EPM2A,PHTF2" Drug 4981_DN Harpagoside [19210-12-9]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ABAT,AK2,MRTFA,ANK3,EP400,CDC14B,RGS20,ATM,CFLAR,CACNA1D,CAMK2G,SLIT2,HP1BP3,DTNA,EDNRA,MBNL2,IRAK4,FER,FAM49B,GRB10,GRIK5,CACFD1,IL6ST,ITPKB,N6AMT1,ZNF862,NF1,NPTX1,NRGN,NUMA1,LRP12,MINDY2,PTHLH,RGS10,ROM1,FBXW7,SLC1A7,PREX2,BTBD7,WDTC1,ZCCHC24,EMC1,SS18,MCF2L,TBL1X,ZKSCAN5,VAV2,VIPR2,WNK1,EVI5" Drug 7104_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ADRB2,APP,LGR5,SHROOM2,ASPH,ALDH4A1,CFLAR,AP4M1,MAGI1,RCBTB2,CHN2,CNOT8,HOMER3,NRG2,VCAN,KIAA0513,MAMLD1,SCARA3,DPYSL4,TRMO,GBX2,SRCAP,STON1,CACFD1,SLC2A6,SCIN,IL11RA,GIT1,SLC11A2,CDK14,VPS13C,PTX3,SH3TC2,ZCWPW1,TMEM156,TMCC1,DOP1A,SPTAN1,IQCE,SYNE1,ARHGEF12,TMEM121,TNS1,TPM2,TRPC1,WNT7A,PRDM2,PDSS2,SMIM8,IFT88" Drug 5620_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "DPF1,ANK1,KCNAB2,APC,CDC14B,PDXK,ASPH,ADAM23,CFLAR,KSR1,NEURL1,KCNAB3,CNTFR,PHF14,CTIF,GIT2,EDN1,EGFR,EGR3,CORO2B,AGAP2,GAB1,POLL,CNTRL,ATXN2L,HLF,BCO1,TAGLN3,NF1,NOVA2,NTRK2,CDK18,PFKFB2,PURG,PRKCB,CNNM2,PTPRE,ASIC4,MRAS,LIMCH1,KIF13A,KDM4B,ZHX3,PHLDB1,TAC3,DAAM2,TTPA,SPHK2,SEMA3B,NAV2" Drug 3386_DN Propofol [2078-54-8]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "NME5,AK2,BIN1,APBB2,APC,APLP1,FAM131A,ATM,SLC2A11,CFLAR,SCAPER,CACNA1D,GREB1,NOS1AP,MAML1,ZNF804A,DMPK,DTNA,RBM12,SUGP2,FGFR1,FAM49B,TRAF3IP2,ALDH1L1,MALT1,ADAM22,CDK18,RETREG1,PMP22,LRP12,RETREG2,MBOAT7,GRAMD1C,RAB3IL1,RGS10,ZFHX4,TCP11L1,RASA3,FAM214B,KIF13A,ZNF423,ZBTB43,EXOC7,KIAA1107,TBCEL,DMXL2,TCF7,ZMYND8,PDIA2,SSPN" Drug 5575_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "ADCY2,ADORA2A,AGT,APBA2,APC,DNAH17,RASL11B,BACH1,RGS11,LDLRAD4,CBFA2T2,WHRN,OSBPL3,CHD5,NCAN,PDE4DIP,HDAC9,DCC,EXOG,EDNRA,MBNL2,ZNF589,AFF2,GABRA2,SRCAP,GNAL,GRIK1,GUCY1A2,C2orf72,KCND3,KCNJ4,MSR1,TAGLN3,NOVA1,P2RY1,PDGFRA,PFKFB4,PURG,KCTD17,CNKSR2,PKNOX2,KIF21B,BEX1,ATP10B,TRIM2,SYNE1,HIF3A,HEY1,TRPM2,UCHL1" Drug 7191_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "NDRG2,MTUS1,APOC1,CDK13,MARK4,ASPH,ATP2B2,BTRC,CBFA2T2,FAM189A2,CSF1,PDE4DIP,EDRF1,RCAN1,DTNA,MBNL2,COQ7,CDKL3,VPS26C,ACSL4,BAIAP2,FHL1,MALT1,COPS8,GRK4,GRB10,GSN,KCNH2,KIFC3,LSS,MAP4,MPP2,PPP1R1A,SAMD9,PTPRN2,RGS12,CCDC25,WLS,SEC14L1,ZFP30,ZNF365,SLC11A1,RBM34,MAPK8IP3,PLCB1,TRPC1,VIPR2,MAP3K12,EMSY,SEMA3B" Drug 1165_UP trifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.55E-04 1.00E+00 1.54E-03 1.75E-02 50 192 "AMT,GAS7,ARNTL,NCOA1,CDO1,SOCS6,RAB28,SULT4A1,AKAP7,IQCK,COL9A2,DZIP3,CTH,HDAC9,KIAA0753,RCAN1,DTNA,PLXNC1,ELAVL2,EPB41L2,CAP2,CGREF1,SRCAP,ZNF276,GLYR1,LPAR4,FICD,HMGCR,LSS,ZNF862,P2RX7,ENPP2,CCSER2,RGS10,RPS6KA2,RBM34,SPP1,ZBTB43,FCHO1,MAPK8IP3,ARHGEF9,TCF7L2,ZMAT3,TMOD1,TPD52,PLPPR2,NPDC1,ZBTB38,EPM2A,PHTF2" Drug CID000024572 lead arsenate Stitch 1.56E-04 1.00E+00 1.54E-03 1.75E-02 28 89 "SERPINA3,ACHE,APLP1,APOC1,BCHE,RUNX1T1,NOG,CLU,CNR1,CX3CR1,BLOC1S6,DMD,DTNA,DTNB,FOXM1,PDLIM5,HBA1,HPS5,IL6ST,ZNF331,SNRPN,DDN,SYP,TPM1,TPM2,ZIC1,HPS4,NETO1" Drug 7174_UP Cinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,ADCY6,ADORA1,KIDINS220,AK2,FAM131A,ATM,CCDC181,BACH1,MPDZ,CFLAR,SCAPER,BAIAP3,CA12,SCARB1,ARHGEF2,RCHY1,PDE4DIP,SPOCK2,CTIF,HP1BP3,PARD6A,DLG3,CDON,DTNA,EGFR,EGR3,CDKL3,ANKMY1,FGFR1,FAM49B,SRCAP,TXNL4A,GLYR1,NR3C1,LIG4,MMP16,OMG,PAX6,MAPK8,RGS12,TCP11L1,SBF1,ZNF365,PPP4R3A,COA1,TSPYL2,SEMA4A,TK2,LILRA4,TIGD6" Drug 3889_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AMPD3,PRX,MARK4,CACNA1I,CFAP410,CNTN1,FAM149A,MYRIP,OSBPL3,RASSF2,DYNC1I1,SHANK1,C3orf18,EPB41L1,TUBB4A,FGFR3,PDLIM5,MSL3,POLL,GPM6B,TDRKH,PCLO,GRIK5,RNFT2,ICA1,KIT,SMAD1,MN1,NNAT,PALM,PAX6,PFKFB2,NECAB2,C19orf57,PTPRN2,MARCH1,C1orf54,ZMAT4,TRIM68,BCAN,RPH3A,LIMS2,KDM4B,WDTC1,IZUMO4,SAMSN1,WSCD1,ICAM5,TRIO,LAT2,MVB12B" Drug 2796_DN Bicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ABHD6,AP2A2,CDC42BPA,PPFIA3,ARHGDIG,ALDH4A1,BMP7,BTRC,CCNT1,USP2,ZFYVE9,DNAJB5,HOMER3,ENTPD4,FEZ1,CTH,EDRF1,DBN1,DSCAM,SIDT2,EFNA3,EGFR,ERBB2,ZNF589,FGFR1,BAIAP2,SEMA4D,B4GALNT1,TXNL4A,CACFD1,GSN,DHX35,IGSF1,KPNA5,MATK,OGG1,POLG,PEX5,RALGDS,FBXW7,ITSN1,ZNF365,WDTC1,TROVE2,KANK1,EXOC7,RPGRIP1L,PARD3,REEP1,WNK1,SENP7" Drug 2845_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "SEMA6A,SRPX,APC,ATP6V0A1,KIF1A,CFLAR,SYNJ2,MTMR2,CFAP410,CAMK2G,CLGN,IQCK,RCHY1,DZIP3,PPP6R2,DAPK3,GIT2,MFAP3L,EDNRA,MBNL2,IRAK4,DMTN,FAM198B,DISC1,INPP5K,SRCAP,POLL,NR3C1,SLC2A6,HNMT,LIG4,NRGN,SETD4,ZSCAN32,ZSCAN2,CEP97,RXRA,SBF1,ANKRD6,ZNF365,BTBD7,GLT8D1,EMC1,VPS13A,ARC,EXOC7,SLC44A1,TMOD1,VGF,EPM2A,UBE3B" Drug 5009_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADCY6,NME5,ARRB1,SLC4A4,KYAT1,CBFA2T2,SCARB1,RAB28,STOML1,CSF1R,MICAL2,PDE4DIP,SDC3,TBC1D5,HIPK3,EGFR,MRNIP,PLEKHO1,ZNF589,FHL1,SYT17,SRCAP,MALT1,GLYR1,RAB30,GNG3,NR3C1,INPP5B,JAK2,KITLG,MMP16,NFYA,NTRK2,RETREG1,PLCD1,POLG,CEP97,CPEB3,FUZ,FNDC3A,FAM214B,SLN,RBM34,ZCCHC24,ZHX3,LHPP,TGFBR3,CDK20,VAV1,VGF,SMIM8" Drug 2371_UP Lisinopril [83915-83-7]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "PRX,C5,CACNA1D,MAP7,VAX2,FAM149A,AKAP6,ATRNL1,PPP1R16B,ERC2,NOS1AP,MFAP3L,DTNA,DYRK1A,EFNA3,LRRC23,CDKL3,FOXG1,GPR153,GALC,ALDH1L1,GLYR1,GPM6B,GRIK5,GRM7,GRM8,NXPH3,ATXN2L,KLF12,KCNH2,KCNN1,NPR2,PDZRN4,MINDY2,CNTLN,RGS3,TTLL7,SYNDIG1,SH3BGR,LIMS2,CXXC4,RBM34,SOX15,RAP1GAP2,SEPT8,PDLIM2,IQCE,WSCD1,ZNF34,FLRT2,SPHK2" Drug 2181_UP Sulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,CDC42BPA,ARHGDIG,AZGP1,BMP7,CDK5R1,MAP7,SLC16A4,CHM,EPS15L1,ZFYVE9,CLCN4,STOML1,SIPA1L1,PDE4DIP,EDRF1,SPOCK2,OPTN,CAMSAP1,FOXG1,IQCG,PDLIM5,GATM,ZNF276,GRM1,KIF5A,PLEC,SLC25A23,PPP2R2B,RGS12,KCTD17,MYH14,MRAS,RASA3,FERMT1,SNCA,DOK5,HECW1,SPTB,WSCD1,ATP13A2,TGFBR3,TPM1,FAM155A,FLRT2,LMF1,XRCC4,ZBTB16,KCNAB1,FZD3,KAT6A" Drug 1947_UP Hesperetin [520-33-2]; Up 200; 13.2uM; PC3; HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,ADORA1,PPFIA1,APOC1,ATM,CA12,CBR1,KRIT1,P2RX6,TBRG4,NMT2,CRY2,OSBPL3,FAM169A,GIT2,RUSC2,MED12,DPYSL2,DTNA,E2F5,EPB41L2,ERCC2,CINP,PDLIM5,DENND2A,SPIN1,GPER1,GSN,SLC2A6,KIF5A,PLCD1,ZNF426,CNNM2,SIDT1,PEX5,ARID4A,ZNF821,GALNT10,AMBRA1,KBTBD4,TSPYL2,ARHGEF12,HEY1,PARD3,LMF1,WNT7A,UPF3A,NAV2,ITM2C,MVB12B,ZNF248" Drug 3832_UP Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RGS20,SLC2A11,N4BP2L1,MYRF,CCKBR,CHRNB2,NOS1AP,CTIF,RUSC2,TMCC2,HS3ST2,ERCC2,F5,ATP8A1,C1orf61,CAMKK2,FUT9,GLYR1,POLL,GNAL,NR3C1,DHX35,IL6ST,KCNH2,KCNK2,TM6SF1,MGAT3,KITLG,AFF1,OMG,OPCML,CLDN11,PIK3CD,TNPO2,PPARA,PRKCB,PTAFR,PTPRD,PTPRO,RGS12,SCN8A,SLN,RBM34,SSTR2,INKA2,WSCD1,FLRT1,PLPPR2,VAV2,ZBTB38,NLRP3" Drug 3940_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,PLA2G6,C1QTNF3,GAS7,APP,PLA2G4C,ASPH,SYNJ1,SCAPER,CDC42,TAOK2,CLCN4,CPS1,ARHGEF10,PDE4DIP,DAPK3,C2CD2L,ATN1,DSCAM,LRRC23,KIAA1109,C1orf61,KHDRBS3,GPR153,GAB1,GAD2,RND1,GRIK5,KCNJ3,KCNMA1,KCNN1,KCNQ3,MAP4,MSR1,PCDHGC3,SERPINI1,SLC25A23,MTRF1L,MINDY2,MAPK8,PLPPR1,FAM120C,ZDHHC14,PPP1R9A,MAPKBP1,KIF13A,DOK5,ARC,ITM2C,PHTF2,NUP214" Drug 5949_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NME5,MRTFA,EIF4G3,CFLAR,SCAPER,MYRF,CAMK2B,CBS,SCARB1,NEURL1,ARHGAP33,B4GALT6,CABP1,DRP2,SIDT2,AASS,BAIAP2,FOXG1,CGREF1,OGA,FYB1,ERAP1,GLI2,ELOVL5,MITF,MMP16,NF1,NPR2,CEP41,GRAMD1C,BCAS3,PTCH1,FAM120C,TMEM231,RGS10,SYNDIG1,DZIP1,LIMS2,SPATA7,ARHGAP26,CEP68,SYN2,EXOC7,SMG6,TMOD1,TRIO,ZMYND8,RPRM,ZNF24,ZNF74,HPS4" Drug 2641_UP Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RALGAPA1,ADCY6,SYT13,MRTFA,KCNAB2,PLA2G4C,CDK5R1,BAIAP3,CA4,CAMK2B,RUNX1T1,ARHGEF1,TAOK2,VCAN,PDE4DIP,CTNND2,RIMS2,EDRF1,KIAA0586,DBT,DCT,JAKMIP2,DYRK1A,PLXNC1,HSD17B14,FGFR1,PRELID3A,SIGLEC8,INPP5K,GLS,GRM8,GSTM5,IL6ST,KCND3,MGAT3,CD200,ADAM22,NOVA1,NUMA1,PLCD1,ZSCAN2,FAT4,ZMAT4,RGS12,FRMPD1,RPH3A,ZC3H13,TCF4,TRIM2,DOCK9,TRPC1" Drug 7434_DN Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AP2A2,APC,FAM131A,APOC1,CDC14B,BCL7A,ST3GAL5,AP4M1,ADGRG1,COL9A2,CREM,PDE4DIP,PPP6R2,EDRF1,GPRASP1,PARD6A,SEZ6L2,RBM12,APH1A,SORBS3,IRAK4,EFEMP1,CRCP,HNMT,KIF5C,MAP4,MIA2,NPR2,PBX1,SLC25A23,RETREG2,POLG,LRRC49,CEP97,CCDC25,FBXW7,FBXO11,NUBPL,SLC20A2,SMARCA4,SPATA7,MAPK8IP3,PHLDB1,FAM168A,TCF7L2,TRIM2,TIAM1,KCTD2,PARD3,KAT6B,SF1" Drug 1151_DN alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,ADD1,C1QTNF3,APC,ARRB1,ZBTB10,N4BP2L1,SYNJ2,OSGIN2,TMEM184B,SOCS5,C2CD2L,RHOBTB1,SUGP2,ABI2,F3,FECH,CGREF1,ERAP1,DISC1,GLYR1,GLS,MUM1,AGBL5,SMAD1,SLC11A2,PDE4A,PTPA,PPP3CB,PRKAB2,PTPRO,UEVLD,SBF1,ATXN2,AMBRA1,DZIP1,ARHGEF40,TMCC1,CAMTA2,NCDN,SEPT8,FAM168A,VPS13A,ATP11A,TCF4,TCF7L2,TGFBR3,ATP6V0E2,PRDM2,PDSS2,MARCH8" Drug 6842_DN Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ALAD,ALCAM,AMPD3,MARK4,EIF4G3,CFLAR,SYNJ2,CDC42,CACNA2D2,NMT2,CRY2,CSNK1E,RIMS2,KIAA0586,CNNM1,ING4,KAT8,ZNF589,FGFR1,CAMSAP1,PDLIM5,GFER,POLL,CNTRL,ADAMTS13,GSN,ATXN2L,KCNH2,MAPT,NPR2,PCBP3,NUCB1,PDE3B,RETREG1,RAB3IL1,CEP97,SH3BP2,COA1,SNCA,EMC1,KDM4C,SAMSN1,VAMP1,PLCB1,PSD3,TMEM121,VGF,LMF1,ZNF189,EMSY,SMIM8" Drug 5863_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ACTN1,AGT,BIN1,APC,GAS7,BMP7,CACNA1G,BRSK2,CDH8,CLCN4,SULT4A1,RAB26,CTNND2,GPRASP1,HDAC4,MFAP3L,DNAH9,CNNM1,SORBS3,HSD17B14,EPHA5,BAIAP2,SCARA3,DCTN2,PNMA2,FYB1,GLI2,STON1,GPR37,SOX21,SCIN,MT1M,MX1,NTRK2,PDE4B,ENPP2,SAMD9,PTPRE,MYH14,TMEM206,NEK11,MAPK12,CCDC88A,BTBD7,NPAS3,ATP10B,COBL,KIAA1107,TMEM121,HPS4,KCNAB1" Drug 2972_DN Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ABAT,NDRG2,ADORA3,MTUS1,CASK,ATP6V0A1,SCAPER,CFAP410,CAMK2G,MAP7,SLC16A4,CD86,CLGN,FOXN3,STOML1,PDE4DIP,PPP1R16B,CTNND1,ZNF337,DGKG,DLG4,SUGP2,EZH1,FGFR1,CGREF1,ADAM28,ELOVL5,MAP4,SCAMP5,SLC11A2,OGG1,OLR1,PFKFB4,PLEC,POLG,TMEM231,CEP97,ZCWPW1,BEND5,TCP11L1,PAQR6,ITSN1,ANKRD6,MAPKBP1,DOP1A,WDTC1,TNIK,DDN,TCF7L2,AP4E1,MAP3K12" Drug 6679_UP Diloxanide furoate [3736-81-0]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RALGAPA1,ADRA1D,LTBP4,ANK2,KCNAB2,ARRB1,RASL11B,ATP2B2,ATP6V0A1,SYNJ1,GYG2,CACNG1,KALRN,CRLF1,NRXN3,SRGAP3,CDON,DUSP9,F5,DKK3,GAD2,SIGLEC8,LYVE1,SPACA9,CACFD1,ATXN2L,IRF8,KCNC1,MDM4,MGAT3,ADAM22,NCAM1,NPY,NPPA,CLDN11,GPR85,ZSCAN2,ENOX1,RGS7,TCP11L1,STUM,SLC6A9,SLC11A1,SLCO1A2,SNCA,KAZN,EXOC7,ICAM5,TLR4,SPHK2,PARP11" Drug 5803_DN Propidium iodide [25535-16-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "APBA2,APC,CDC14B,MARCH3,ALDH4A1,RAB28,NRXN3,DNAJB5,SDC3,ARHGAP24,MFAP3L,SPOCK3,DLG3,TOM1,HIPK3,FAM13A,AASS,SORBS3,STX2,FGFR1,SORBS1,DENND2A,TMEM8B,SRCAP,PCDH17,ZNF276,GPM6B,IL6ST,KIF5C,MIA2,MT1M,LYRM9,MYO6,NDUFA5,NF1,PBX1,PC,SERPINI1,MAPK7,PTPRN2,PEX5,RALGDS,FBXW7,FUZ,KDM4B,ZNF423,SYT1,COBL,TBCEL,ZBTB14,KAT6A" Drug 4560_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "TRMT9B,BIN1,PKP4,APC,CDC14B,BAIAP3,CBFA2T2,CACNA2D2,NRXN3,AKAP7,COL9A2,NRG2,PDE4DIP,CNTNAP2,RUSC2,TMCC2,ATN1,EDNRA,PLXNC1,AASS,SORBS3,TNK2,CDKL3,ANKMY1,FKTN,CINP,PRELID3A,GPR37,GRM1,SHISAL1,IL12A,MEF2C,MX1,MYO7A,RAB3IL1,RGS10,SUGCT,DCUN1D2,RXRA,ATXN2,DZIP1,SLC4A3,SLC1A7,SNCA,IQSEC2,PHLDB1,SYT11,KIAA1107,SLC44A1,TNS1,CADM1" Drug 6768_DN Tamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ABHD6,SEMA6A,BIN1,APC,ARHGEF7,GYG2,CA12,MAGI1,SOCS6,SLIT2,EPS15L1,PLAA,QKI,PICK1,AKAP12,FEZ1,CSNK1E,SDC3,GREB1,DCAF8,ZNF337,C2CD2L,EDNRA,SORBS3,PCOLCE2,EML1,FAM198B,FHL1,DPYSL4,MSL3,KCNMB4,RASSF8,ELOVL5,KCNF1,LSS,GIT1,ADAM22,NOS1,SERPINE2,LRP12,ELOVL2,FAM184A,RET,SBF1,LIMCH1,ARHGAP26,ARC,AP4E1,HIRA,TFIP11,UBE3B" Drug 6744_DN Metergoline [17692-51-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "C1QTNF1,ALAD,CDC14B,ARHGDIG,PDE8B,MARK4,ATP1A3,ADAM23,SYNJ1,CACNA1I,MYRF,B4GALT6,WHRN,CRMP1,ARHGEF10,CNTNAP2,GPRASP1,BRINP1,MTSS1L,ZNF549,TRAF3IP2,SEPT9,GLYR1,GPM6B,STON1,GRK4,GRM8,TJAP1,SCIN,MGAT3,MYT1,NF1,SNTG1,KCTD15,PRKAR1B,FAM120C,KHDRBS2,RGS10,FOXRED2,ATXN7,FRMPD1,EPN2,BTBD7,TSNAXIP1,LHPP,MAPK8IP3,DOCK9,TNS1,VGF,VIPR2,KCNAB1" Drug 6291_DN Chlorpropamide [94-20-2]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AP1B1,BIN1,PPFIA3,MARK4,MTMR3,MAP7,KYAT1,RAB28,ZFYVE9,ARHGEF4,ZNF337,RIMS3,GIT2,B3GAT3,RHOBTB1,DPH1,OPTN,SUGP2,DENND4A,ANKMY1,KIAA1109,FHL1,TPK1,TXNL4A,GPR37,GUCY1B1,MAN1B1,JAK2,KCNMA1,MID1,MPP2,TAGLN3,SLC11A2,PIK3R1,SMIM7,FSD1,MINDY2,PTPA,PRPH,CNNM2,BSDC1,TRIM68,SUPT20H,SRPK2,STX1A,SYT11,KIAA0930,TRIM2,TNS1,METTL3,XRCC4" Drug 2455_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ACTN2,NDRG3,MTUS1,APAF1,APBB2,APC,ALDH4A1,CFLAR,BMP7,FUBP1,SLC16A4,LARGE1,CHM,CNOT8,PICK1,RCHY1,HAPLN1,FAM131B,DBT,DTNA,SORBS3,MRNIP,EIF1,PTK2B,KAT8,KIAA1109,PDLIM5,CAMKK2,GART,GNAL,GPM6B,HSF2,KCNJ5,NNAT,NECAB2,PRPH,ASIC4,SMTN,IZUMO4,ATP10B,SS18,NXT2,RPGRIP1L,RBFOX2,NSD2,ZNF24,MKRN3,REEP1,KCNAB1,ACTR3B,SENP7" Drug 2836_UP Benperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,MRTFA,AQP4,CDC14B,PLA2G4C,ATM,CFLAR,RAB29,CA12,CACNA1D,ARHGEF2,FOXN3,GREB1,RIMS3,SGK2,NCALD,OGA,GAD1,SYT17,SRCAP,GPR22,GRIK1,GSN,SLC2A6,IRAK3,ELOVL5,IL6ST,MAOB,MITF,AFDN,CD200,ZNF862,PCBP3,NTRK2,PIK3CD,PRKAR1B,RGS12,RASA3,SCG5,DZIP1,PEX26,ZBTB43,ABCC8,VAMP1,POPDC3,CRTC1,SLC35G2,DICER1,ICAM5,WIPF1,KCNAB1" Drug 6466_DN Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASPHD1,AK2,TRMT9B,AMPD3,BIN1,APC,ATM,RIPK1,CFLAR,LDLRAD4,B4GALT6,CLCN3,PUM1,NOS1AP,MFAP3L,FEM1B,EGFR,PLXNC1,STX2,NCALD,F3,FGFR1,HNMT,IL6ST,MEIS1,MGAT3,NELL2,NPR2,PDE4B,PPP5C,ZSCAN32,RAD52,KHDRBS2,RGS3,RGS10,SLC25A36,DCUN1D2,BCAN,SOX2,DOK5,IQSEC2,POGZ,NCDN,MCF2L,TCF7,TCF7L2,SLC44A1,THRA,ZMYND8,SEMA3B,SMIM8" Drug 5752_DN Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,ALK,CDK5R1,BTRC,CDC42,CRLF1,CHM,DNAJB5,ENTPD4,EDRF1,MFAP3L,TESK2,FGF1,BAIAP2,CGREF1,GBX2,GPD2,GPM6B,TDRKH,HSF2,IFI16,NF1,CLDN11,PTHLH,RAD51D,RGS7,KCTD17,SUGCT,MYH14,ROM1,RPS6KA2,SBF1,ATXN7,SH3BP2,KIF16B,SLC1A7,KBTBD4,SLC14A1,BTBD7,IFT122,SNCA,ZNF415,ZBTB43,SS18,MAPK8IP3,COBL,FBXW11,ARHGEF12,CHST8,VGF,PHTF2" Drug 2954_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADD2,MRTFA,AMPD3,SYNGR3,CHRNB2,ZFYVE9,CLCN4,SULT4A1,CREM,ABCG1,CTIF,SMG7,SPOCK3,SORBS3,ALDH1L1,SRCAP,KCNMB4,ATF7,PCLO,TPPP,PTGDR2,MAN1B1,KCND3,KCNK1,LAMA2,SHC3,MGAT3,AFDN,MMP16,GIT1,CNOT4,OPRL1,PCDH9,PFKFB2,SERPINI1,POU6F1,PRKAR1B,BCAS3,RAD52,MRAS,SLC11A1,SHANK2,CXXC4,ZHX3,IZUMO4,SPTB,SYNE2,SLC44A1,TNNT1,RBFOX2,FAM155A" Drug 6314_UP Vigabatrin [60643-86-9]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "PLA2G6,TRMT9B,SEMA7A,APAF1,ASCL1,SYNJ1,CACNA2D1,CBFA2T2,PLAA,TPP1,HAPLN1,ABCG1,PDE4DIP,HDAC9,ARHGAP32,CTIF,EFNA3,EFNB3,COQ7,KIAA1109,BAIAP2,C1orf61,INPP5K,ZNF276,HSF2,IL6ST,MYO7A,NF1,NUMA1,ODF2,GPR85,PLCD1,PPP2R2B,MAPK10,BCAS3,PLPPR1,RAB3A,RAD52,DZIP1,ELMO2,TTC17,TAB2,PHLDB1,SMG6,THRA,TPM1,TPM2,AMACR,NDRG4,NT5M,EVI5" Drug 2259_DN "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RALGAPA1,NME5,FAM131A,APOC1,MARK4,ALDH7A1,HAP1,CCNT1,ARHGAP33,CRLF1,CACNA2D2,FOXN3,SOCS6,CTH,GREB1,EGFR,EPB41L1,CAMSAP1,SORBS1,SRCAP,MALT1,KCNK1,KCNN2,MAP4,MDM4,ZNF862,PIK3CD,MAPK10,GRAMD1C,TMEM104,RGS10,MYH14,GSTCD,SBF1,SH3BP2,FERMT1,SIRT2,LIMCH1,WDTC1,STX1A,DOCK9,PSD3,THRA,TPM1,WBP2,SPHK2,SLC30A3,WNK1,KCNAB1,KAT6A,JPH3" Drug 5404_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,NDRG2,ADRA1D,C1QTNF1,FAM135A,MRTFA,AMT,CDC14B,ASPH,CFAP410,CAMK2B,NEURL1,CHRNB2,TPP1,CLTB,ABI3BP,NCOR2,KBTBD11,ELN,EN2,DLC1,ATP8A1,TMEM8B,GLS,CNTRL,RASSF8,KLF12,IL11RA,INPP1,PDE3B,EPN1,PLP1,PLXNB1,PURG,LRP12,PTN,RASGRF1,RFX2,BCAN,SLC11A1,DOK5,RGL1,MLC1,SYP,POPDC3,ROBO3,WSCD1,PCDHGA1,PCDHA5,NLRP3,DPF3" Drug 6664_UP Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADORA3,KCNAB2,APBB2,PPP4R4,N4BP2L1,BMPR1B,CFAP410,CBS,DNAJB5,IFFO1,CSF1,BRINP1,MFAP3L,SV2B,DMPK,DUSP9,PLEKHO1,FOXG1,ERGIC3,TBR1,IQGAP2,ALDH1L1,POLL,CACFD1,HTR2A,KCNJ3,KIF5C,AFDN,MMP16,CD200,ADAM22,PDE4B,TNPO2,MAPK8,PTN,PTPRN2,KHDRBS2,ZNF334,SNCA,ZFPM2,AP4E1,TIMP4,DAAM2,R3HDM1,TPM1,ZNF74,ZNF225,PRDM2,KCNAB1,CAB39L,CAMK1G" Drug 5808_UP Tomatidine [77-59-8]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADGRF5,SLC4A4,RGS9,CFLAR,ST3GAL5,CACNB4,BRSK2,SEPT7,CHN2,CLCN4,ABCG2,IQCK,CRMP1,GIT2,DBT,CNIH3,CDON,SEMA4D,PDLIM5,FYN,SYT17,SEPT9,LYVE1,GLI2,PRUNE2,GPER1,GPR37,INPP5B,KIF5C,LIFR,MT1M,TAGLN3,SNTG1,SERPINI1,RETREG1,WDR25,PID1,FAM184A,SUGCT,ASAP3,FNDC3A,TMCC1,KIF21B,ZC3H13,ARC,SYN2,SYT1,TRIM2,CLDND1,WNK1,MAP3K12" Drug 4976_UP Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,NDRG2,NME5,LTBP4,APC,PPFIA3,APP,SEMA4G,CDK13,ASPH,ASTN1,CDK5R1,LDB2,CBFA2T2,ARHGAP33,CHRNA4,HOMER3,CSF1,CTH,RIMS2,EXOG,SIDT2,EFNB3,FGF13,GLYR1,GPER1,GRIK1,KCNN1,MOBP,MYO9A,CNOT4,P2RY1,SERPINI1,RETREG1,MINDY2,CEP41,PTAFR,PTPRO,ZNF493,ZFHX4,SLC11A1,DOP1A,ST5,ARHGEF9,WDR7,PARD3,PIK3R5,KLC2,SLC17A7,KCNAB1,PHTF2" Drug 703_DN genistein; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RBM10,BRAP,BIN1,CDC42BPA,CNTNAP1,PPFIA3,SLC4A4,EIF4G3,MPDZ,BCL7A,ADGRG1,EPS15L1,NCOR1,SDC3,PPP6R2,SMG7,ELAVL2,COQ7,FGFR1,NCKAP1,GBX2,RUNDC3A,TXNL4A,CRCP,BTN2A1,HAS2,HMX1,JAK2,KCNJ5,MTR,NELL2,OMG,PBX1,MAPK7,MAPK10,RBBP6,NUDT11,CLIP1,SBF1,MAPKBP1,ZHX3,CLASP2,EXOC7,FBXW11,ZEB1,HEY1,KCTD2,TRIO,WIPF1,NPDC1,REEP1" Drug 6091_DN Nadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,ALCAM,BIN1,APBA2,KCNAB2,ARHGDIG,DNAH17,MARK4,SLC4A4,EIF4G3,ADAM23,NEURL1,TAOK2,VAX2,CNTN1,CSF1R,PDE4DIP,RIMS2,TMCC2,KBTBD11,PLXNC1,SCML2,DISC1,ALDH1L1,GLS,MSL3,GNG3,CNTRL,INPP1,INPP5B,MMP16,NF1,MAPK7,PRODH,TMEM104,RALGDS,SBF1,PREX2,BTBD7,SNCA,ZHX3,KDM4C,FCHO1,MAPK8IP3,EXOC7,PCDHA5,SLC44A1,TMOD1,ZKSCAN5,VIPR2,EPM2A" Drug 6203_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ARID1A,SEMA6A,BIN1,APBB2,CDC14B,SLC4A4,BMP7,CACNA1I,BTRC,CACNG1,NEURL1,SEPT7,CDO1,ASIC3,CLCN4,SULT4A1,CNTFR,WHRN,CSF1,ECM2,EDNRB,SORBS3,VPS13B,RASGRP2,ERBB4,CAP2,AGAP2,PCLO,PTGDR2,MPP2,NOS1,PCSK1,CCSER2,RETREG1,MARCH1,STUM,SH3BP2,FRMPD1,FAM214B,SLCO1A2,SORCS3,SS18,TCF4,DMXL2,DICER1,CHST8,SLC44A1,TK2,TPM3,TUBB1,PRDM10" Drug 2269_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "RALGAPA1,SEMA6A,LTBP4,AMPD3,APBA2,APBB2,RASL11B,ATM,CFAP410,CA4,ARHGEF1,FOXN3,SLIT2,TPP1,CSNK1E,MFAP3L,HP1BP3,RCAN1,CDKL3,VPS26C,FER,KIAA1109,FOXG1,FAM49B,GPR153,SRCAP,GLYR1,MSL3,GNG4,SLC2A6,JAK2,KCNN2,MSI1,ADAM22,ZNF862,MYT1,NUMA1,PLCD1,MAPK8,PRODH,PTHLH,PREX2,PEX26,PPP4R3A,WDTC1,KDM4C,VAMP1,PLCB1,UBTF,VAV1,WIPF1" Drug 3485_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,ABHD6,C1QTNF3,CNTNAP1,APAF1,APLP1,BACH1,CFLAR,RCBTB2,CNOT8,SPOCK2,DUSP9,CNNM1,PLXNC1,ACSL4,SCML2,GFER,GPM6B,STON1,JAK2,KIT,TM6SF1,ADAM22,NF1,PC,PPP3CA,GRAMD1C,SAMD9,FAM184A,TCP11L1,RPS6KA2,FBXO11,ANKRD6,SMTN,FAM214B,BTBD7,SMARCD3,TMCC1,KDM4C,MAPK8IP3,DIP2A,PHLDB1,VPS13A,TACC1,EXOC7,KIAA0930,PCDHA6,HEY2,REEP1,TFIP11,WNK1" Drug 4832_UP Indoprofen [31842-01-0]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "KIDINS220,AP2A2,APC,PRX,CDK13,CFLAR,QKI,COL9A3,BAG4,CRY2,DCAF4,RIMS3,DAPK3,ATN1,RRAGB,ANKFY1,TRMO,GAD1,GLYR1,SYNPO,IL6R,LMO2,LSS,MDM4,MMP16,BCO1,NNAT,NPTX1,NUMA1,P2RY1,PRKAR1B,MAPK7,MAPK8,SCN8A,ASAP3,CCDC88A,RBM26,ATP10B,CLSTN2,THSD1,MAPK8IP3,VAMP1,DOCK9,TMPO,TPM2,PDIA2,VAV2,VIPR2,WNK1,NT5M,SCG2" Drug 3934_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ALCAM,MRTFA,ATM,ADAM15,GYG2,LDLRAD4,BTRC,CDC42,B4GALT6,CNTFR,AKAP7,RCHY1,CSF1,RIMS2,TBC1D5,HP1BP3,ATN1,TOM1,HIPK3,EFNB3,ATP8A1,FHL1,KHDRBS3,USP19,GNG4,GRIK5,DHX35,ITIH2,KCNJ5,KCNK2,MAP4,BCO1,PFKFB2,ZDHHC14,RGS12,SEMA6D,SH3BP2,FERMT1,NLGN1,FAM214B,MAPKBP1,KDM4B,SPTAN1,PHLDB1,EXOC7,TRIO,VAV1,SPHK2,WNK1,SLC17A7,KCNAB1" Drug 5111_DN Scoulerine [6451-73-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ALDH7A1,FUBP1,CHM,KIAA1549L,NMT2,PDE4DIP,EDRF1,RIMS3,SMG7,CDON,HIPK3,ANKMY1,SCML2,BAIAP2,PCYOX1,SEMA4D,GAB1,GLRB,MSL3,POLL,PCLO,GUCY1B1,IFI16,DIPK1A,MEF2C,TAGLN3,NFIX,NUMA1,PBX1,STRN3,PPARA,CNTLN,PTX3,RAB3A,RAB3IL1,BEND5,ZNF671,CSRNP3,SUPT20H,ZFP30,SLC20A2,SMARCD3,CAMTA2,TCF4,TCF7L2,TMPO,ZNF225,NT5M,SLC17A7,PHTF2,SENP7" Drug 704_DN "ICI 182,780; Down 200; 1uM; PC3; HG-U133A" Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "BRAP,AP1B1,SYT13,MPDZ,CAMK2B,FAM189A2,TJP2,AKAP7,ABI3BP,PPP6R2,SGSM2,TRAPPC9,SGK2,SORBS3,BSCL2,COQ7,TBC1D16,FGFR1,HPCAL4,C1orf61,GBX2,RUNDC3A,KCNMB4,GPR12,BTN2A1,HMX1,AGFG1,KCNJ5,MAN2A2,MAP4,MPP2,ADAM22,NOS1,OMG,POLG,PPP5C,MAPK10,KLK6,RLBP1,ATXN2,FAM102A,ELMO2,MAPKBP1,TNIK,CDK19,ATP10B,EXOC7,KCTD2,NPDC1,ZNF24,WNK1" Drug 542_UP SC-58125; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,ADORA2A,AP2A2,APBB2,ALDH4A1,EIF4G3,N4BP2L1,NRP2,SYNJ2,KYAT1,TAOK2,ZFYVE9,TMEM184B,MAP4K4,CSF1,SOCS5,RIMS2,SPOCK2,BRINP1,C2CD2L,SMG7,DTNA,SGK2,FRY,FAM13A,IRAK4,IGSF6,ZNF589,FLNC,AFF2,ATP2C1,CELF1,CACFD1,PTPRT,KIF5C,NOS1,PBX1,POLG,MED1,MAPK3,DCUN1D2,SH3BP2,ST6GAL1,DZIP1,CDK19,NSFL1C,SEMA4A,TBL1X,TCF4,WRN,HPS4" Drug 4416_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "DPF1,ASIC2,ASIC1,AP2A2,GAS7,APP,CDC14B,SEMA4G,PLA2G4C,MARK4,SYNJ2,SCAPER,CDH8,CHM,SULT4A1,AKAP5,MBNL2,ERBB2,SPEG,FAM198B,KIAA1109,GAD2,ATP8A2,CPLX2,GPR75,GLS,IL11RA,KCNJ3,VWA5A,AFDN,NCF2,ENPP2,PFKFB2,KLHL11,RAVER2,SLC30A10,STUM,SH3GL3,DOCK10,BCAN,SLC1A2,CAND2,HECW1,PEG10,ARHGAP26,RGL1,HEY2,TRPM2,FAM155A,ITM2C,CAMK1G" Drug 3120_UP Esculetin [305-01-1]; Up 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADD2,CDC42BPA,GYG2,BTRC,CA12,CACNA2D1,CACNB2,CAST,INA,AP4M1,ARHGAP33,NMT2,DCAF4,BRINP1,TMCC2,EDNRB,HEYL,EFNA3,CELSR3,RASGRP2,ETV1,ANKMY1,F5,FOXG1,PRELID3A,GPR153,GAB1,GFER,GRIK5,HNMT,ICA1,ITPKA,KCNQ3,MAP4,CNOT4,NPTX1,OMG,PLCD1,POU3F4,LRRN3,BCAS3,MTMR10,FAM184A,CLIP1,FOXRED2,GALNT10,SLC11A1,DOP1A,ZSWIM8,SYNC,PRDM10" Drug 6126_UP Natamycin [7681-93-8]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "BCAR3,FAM135A,APBB2,ADGRB2,PROM1,MYRF,LDLRAD4,BTRC,HAP1,CCK,CDH8,SOCS6,SLIT2,NRG2,ARHGEF10,RIMS2,DNAJC6,HEYL,OPTN,ELAVL3,SRPK3,EIF1,C1orf61,TBR1,C1QL1,STON1,GRM7,SCRG1,KCNB1,SMAD1,OPCML,CAMKV,PPP2R2B,WDR25,RFX2,RGS4,PNMA8A,RYR1,ASAP3,CXXC4,RIMS1,ARHGAP26,SPTAN1,ASTN2,MTCL1,EXOC7,TBCEL,KCTD2,SEZ6L,SPHK2,SLC17A7" Drug 3385_UP Nizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADD2,ADRA1B,C1QTNF1,ALK,DOC2A,RASL11B,SLC4A4,N4BP2L1,CACNA1I,LDLRAD4,CHRNB2,EPS15L1,ZFYVE9,CLTB,QKI,MYRIP,DYRK1A,EDN1,EFNB3,ELAVL3,EPB41,ERCC2,OLFM1,FHL1,NSG1,FUT9,PCDH17,GPER1,NR3C1,KCNJ3,KCNN1,ADAM22,TAGLN3,CLDN11,TREM2,STRN3,CEP41,FAM120C,RPS6KA2,WLS,SALL1,FAM214B,PKNOX2,SLC11A1,SHANK2,OGDHL,FAIM2,POPDC3,PCDHGA10,THRA,SENP7" Drug 7223_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADD2,AK2,ALK,PRX,CAPRIN2,SCAPER,CAMK2A,FAM189A2,VAX2,COL9A3,CRYM,RGS6,CNTNAP2,BRINP1,DCT,EXOG,DMPK,MBNL2,OLIG2,FGF12,GAB1,HBS1L,ATP8A2,SRCAP,RUNDC3A,GPD2,TDRKH,GPER1,GRIK1,IRF8,KCNH2,KITLG,GIT1,NCAM1,NF1,CLDN11,PLPPR1,ZSCAN32,RAB3A,KHDRBS2,RGS4,ZNF821,FAM214B,COA1,LIMCH1,AJAP1,PLCB1,PSD3,TMOD1,UBE3A,GDPD5" Drug 5321_UP Nitrofural [59-87-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ACTN2,ARID1A,APOC1,ASPH,STX16,ST3GAL5,HIP1R,FOXN3,TAOK2,CLTB,CNTN1,DLG3,DSCAM,EFNA3,NCALD,F3,DLC1,FER,POLR1B,STAG2,B4GALNT1,NCKAP1,SEPT9,GRB10,ATXN2L,KCND3,MIA2,LYRM9,NFYA,KCTD15,LRP12,NKAIN1,RAB3A,RPRD1A,RAB3GAP1,TMCC1,WDTC1,POGZ,FCHO1,ELOVL4,TTBK2,SIN3B,TCF7,TRIM2,R3HDM1,ZMYND8,EMSY,GDPD5,HPS4,NAV2,PCBP4" Drug 3234_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AK2,PLA2G6,LTBP4,CDC42BPA,APP,ARHGDIG,ARRB1,CFLAR,SCAPER,B4GALT6,ZFYVE9,HOMER3,CHD1L,CREM,NCOR1,DBT,HP1BP3,FBXL5,DLG3,TRAPPC9,CNNM1,EIF5,RGS17,COQ7,STX2,BAIAP2,SEPT9,USP19,GNG4,GPR37,NR3C1,HNMT,KCNJ3,IPO5,MAP4,MBD1,NFYA,RETREG1,EMID1,SS18,TTBK2,JMJD6,ATP11A,TIAM1,UBTF,VIPR2,ZBTB14,TFIP11,UBE3B,RNF170,SSPN" Drug 5503_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ACTN2,KIDINS220,AK2,APC,APOC1,ATM,SCAPER,KYAT1,TBRG4,CRLF1,EPS15L1,FAM189A2,IQCK,RASSF2,RUSC2,C2CD2L,ATN1,SORBS3,STRADA,FHL1,CGREF1,MSL3,POLL,KLF12,IL6ST,MPP2,NASP,NFYA,NTRK2,OGDH,PDE4B,SLC25A23,PLPPR1,RAB3IL1,ARHGEF10L,SAFB,SBF1,SH3BGR,PREX2,FAM214B,BTBD7,SLC20A2,RBM34,SAMSN1,MAPK8IP3,VPS13A,TMOD1,CDK20,PLPPR2,ZNF24,SMIM8" Drug 6327_DN Nabumetone [42924-53-8]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASPH,CFLAR,CA12,SLC25A14,SPAG9,NFS1,CLCN4,QKI,HOMER3,HAPLN1,SGSM2,LPAR6,ING4,COQ7,ST3GAL6,FCGRT,FECH,FHL1,CINP,CAMKK2,TRAF3IP2,DISC1,GART,GLRB,GPD2,MAP4K5,MAN1B1,DIPK1A,GIT1,MYO6,NUCB1,RC3H2,BSDC1,RGS10,SUGCT,ALG9,CCDC25,ATXN2,FUZ,LIMS2,TNIK,NXT2,FBXW11,TRIM2,PARD3,TPM1,ZKSCAN5,WNT7A,MAP3K12,FZD3,KAT6A" Drug 5610_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADCY6,NME5,AMT,FAM131A,CDC14B,CFLAR,GYG2,CBFA2T2,CLGN,PLEKHB1,STOML1,SH2B1,MAML1,DAPK3,ARMCX2,ZNF804A,MFAP3L,DLG3,TRAPPC9,DRD1,ATN1,DTNA,EFNA3,SORBS3,KAT8,BAIAP2,GAB1,ALDH1L1,COPS8,GLYR1,CACFD1,MBD1,PLEC,SLC25A23,PRKAR1B,NEK11,RPS6KA2,ABLIM3,DHX30,ZCCHC24,MAPK8IP3,ARHGEF9,DMXL2,KIAA0930,ZNF34,BEX4,RUNDC3B,ZKSCAN5,FAM155A,PLPPR2,MPPE1" Drug 5767_UP Retinoic acid [302-79-4]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADCY2,ADORA1,ADORA3,NME5,ALK,BEGAIN,BCAS1,CADM3,BACH1,NRP2,MYRF,CACNA1D,DCLK1,GPR37L1,SLC22A6,COL9A2,SH2B1,NCOR2,FAM131B,ARMCX2,SV2B,DMPK,ATN1,EFNB3,PLXNC1,COQ7,ZNF391,AFF2,PRELID3A,ZMYND11,GATM,NEU3,RND1,GPM6A,GRIK5,IL12A,KCNN1,KITLG,MMP16,CD200,RGS4,MYH14,TCP11L1,EMID1,SLCO1A2,BEX1,RBM26,VAMP1,MCF2L,TRO,SLC17A6" Drug 2782_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NME5,BIN1,APC,CDK13,BMP7,CAMK2G,SPAG9,FOXN3,TPP1,HOMER3,PHF14,GREB1,DBN1,MFAP3L,LYPD1,KBTBD11,SLC12A6,EGFR,FGF12,C1orf61,GPER1,ATXN2L,IL6R,MAP4,MID1,MSR1,MX1,NELL2,NF1,NRGN,SNTG1,PLCD1,MINDY2,CEP41,PRKAR1B,PTHLH,RAB3IL1,SALL1,ZNF821,STUM,FAM102A,PPP1R9A,ASAP3,ARHGEF40,KIF13A,WDTC1,SOX2,MAPK8IP3,RGL1,WSCD1,PSD3" Drug 3983_DN Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "MTUS1,GAS7,CDK10,CHI3L2,ARHGAP22,LHX2,DNAJB5,CRMP1,HINFP,VCAN,EDRF1,ARHGAP32,NR1D2,CDON,DNM2,ATN1,EDN1,MBNL2,EPB41L1,VPS26C,GFER,HTATSF1,SLC2A6,MEF2C,MN1,GIT1,TAGLN3,NOVA1,PBX1,PDE4D,EPN1,GRAMD1C,RAD52,ZCWPW1,RGS4,RGS10,ZNF821,PPP1R9A,SLC6A9,MAPK8IP3,PLCB1,EXOC7,TRIM2,GPR161,THRA,TK2,LMF1,XRCC4,SH3GLB2,EVI5,KCNAB1" Drug 5796_UP Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "DPF1,ADCY2,SPARCL1,ANK1,APAF1,CADM3,MTMR3,MYRF,CAMK2B,NEURL1,CHI3L2,LY86,PICK1,AKAP5,IPCEF1,PDE4DIP,NTM,RABGAP1L,EDN1,COQ7,ZNF549,EZH1,KIAA1109,FGF1,FGR,FOXF2,DCTN2,NSG1,GABRB3,PADI2,ICA1,LAMA2,PDE2A,CAMKV,MAPK7,PLPPR1,RAB3IL1,KCTD17,CARF,SLC11A1,KDM4B,SOX10,HECW1,ARHGAP26,THRA,CHST5,ZMYND8,TMPRSS5,DNALI1,SLC17A7,MVB12B" Drug 3798_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AMPD3,SEMA7A,ATP1A3,NRP2,CANX,PLEKHB1,QKI,AKAP5,TCEAL2,TENM4,MICAL2,RIMS2,EDRF1,GIT2,MFAP3L,PARD6A,DTNA,EDIL3,SORBS3,ING4,ETV1,FOXG1,IQCG,OGA,GNG3,TDRKH,IL11RA,ITGA7,KPNA5,MARK1,SCAMP5,LYRM9,NF1,CNOT4,PENK,NEK11,ZNF821,NTNG1,BTBD7,SNCA,KAZN,IQCE,TRIM2,TRIO,LMF1,ZNF24,EVI5,KCNAB1,KAT6A,PHTF2,DPF3" Drug 3996_DN Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "APBB2,GAS7,APP,SLC4A4,MTMR9,ST3GAL5,BTRC,SLC25A14,CLCN4,HOMER3,WHRN,ARHGEF10,CSNK1E,DZIP3,EDRF1,PARD6A,EN2,ENO2,MFSD10,SPEG,VPS26C,FGF1,ZNF276,MSL3,TDRKH,LPAR4,GPER1,PCLO,BACH2,INPP5B,JAK2,SETD4,PAK3,PCDH9,PDGFRA,PIK3R1,FAT4,ENOX1,GTDC1,MYH14,ASAP3,SHANK2,TMCC1,EMC1,ST5,ZNF34,TRPC1,UGT8,HPS4,MPPE1,PDSS2" Drug 1317_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,BRAP,APAF1,CDK10,STX16,SYNJ2,CANX,SLC25A14,CAPN3,TPP1,IQCK,SEC31B,CSF1,DNM2,EEF1A2,ABI2,PCOLCE2,EIF1,VPS26C,ECSIT,PDLIM5,GART,MAP4K5,AGBL5,HSF2,LIG4,LSS,MAP4,MDM4,NF1,CNOT4,C1orf109,GTDC1,SAFB,SUPT20H,SH3BP2,FNDC3A,ZCCHC24,TROVE2,ZC4H2,NXT2,CEP68,RGL1,MLC1,ATP11A,PDLIM2,FBXW11,TBL1X,UBE2H,NSD2,ZNF32" Drug 341_UP sodium 4-phenylbutyrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASIC1,OSBPL1A,DOC2A,AMPD3,CDC42BPA,GAS7,AZGP1,RAB29,KALRN,NEURL1,ARHGEF2,ZMYM4,SOCS6,CNTFR,DCC,C2CD2L,HIPK3,FEM1B,OPTN,MBNL2,BAIAP2,SEC23B,FAM49B,ZNF638,LUZP2,IPO5,NACA,NAP1L1,NF1,NPPA,NUCB1,OPRL1,MAPK10,PLEKHB2,ARHGEF10L,RMI1,ZNF821,SH3BP2,SLA,ELMO2,KDM4B,ZSWIM8,ZBTB43,ANKRD12,KAZN,EXOC7,EHBP1,SIRT1,ZKSCAN5,FLRT1,MPPE1" Drug 203_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "AK2,MRTFA,CDC42BPA,ARHGAP5,ARNTL,EIF4G3,CADM3,BTRC,CFAP410,TBRG4,DNAJB5,CNTN1,AKAP7,DBT,C2CD2L,DRP2,ANKRD46,EFNB3,MBNL2,EML1,EPB41L2,ANKMY1,F5,PDLIM5,MALT1,RUNDC3A,GPM6B,GRIK5,AGBL5,IRF8,MMP17,NAP1L2,NCAM1,NRGN,OGG1,PAK3,ZSCAN32,PTPRG,SUSD4,GAL3ST4,ZNF331,CHD9,SLC15A2,WDTC1,POGZ,GANAB,TRIM2,TSN,CADM1,ZNF142,ZFAND5" Drug 2800_UP Protoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG2,AK2,BIN1,SCAPER,SGCE,BAIAP3,CAMK2B,CD86,HOMER3,AKAP7,WHRN,CRMP1,ARHGEF4,DCAF4,MBNL2,TNK2,RCAN2,EFCAB2,SORBS1,OGA,GABRA2,GAD1,GAD2,SRCAP,GFER,GLS,C2orf72,KCNB1,KCNMA1,ZNF862,NTRK2,SPATA6,PPP5C,SNRK,RAB3A,KLHDC8A,ROM1,EMID1,PKNOX2,SHANK2,KDM4B,ZCCHC24,PHLDB1,POPDC3,SEMA4A,KIAA1107,PCDHGA10,WNK1,PRDM2,KCNAB1,PARP11" Drug 7360_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ABHD6,NME5,DOC2A,CDC14B,MARK4,BACH1,BAIAP3,BTRC,KALRN,NEURL1,ARHGAP33,FADS2,HOMER3,NCOR2,DNAJC6,PARD6A,DSCAM,GNE,RASGRP2,MTSS1L,EZH1,DLC1,HBS1L,ERAP1,DISC1,GDF9,LPAR4,CNTRL,SPACA9,RNFT2,RASSF8,ATXN2L,ELOVL5,DHX35,HTR5A,MAP4,NF1,PPP2R2B,ZSCAN32,FAM120C,RPS6KA2,ZCCHC24,TSNAXIP1,MAPK8IP3,TTBK2,CRTC1,SLC44A1,MICAL1,EVI5,TIGD6,SSPN" Drug 5435_DN Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASPHD1,AK2,CDK5R1,BTRC,CLGN,SRSF11,B4GALT6,TPP1,QKI,AKAP12,MICAL2,FAM169A,SDC3,DBT,EFNA3,VPS13B,DENND4A,FGFR1,FHL1,TRAF3IP2,GPD2,GPM6B,ELOVL5,HNMT,DHX35,INPP5B,KPNA5,KITLG,NDUFA5,NF1,SERPINE2,SLC25A23,PTHLH,ATG16L1,RGS10,FUZ,AMBRA1,PPP4R3A,ZKSCAN3,SPART,INKA2,PLCB1,MTCL1,EXOC7,PCDHA6,SLC44A1,SPHK2,EVI5,GDPD5,SEMA3B,KAT6A" Drug 3615_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NDRG3,LTBP4,BIN1,EPB41L5,PPP4R4,ASPH,ADAM15,CLGN,ADGRG1,CHM,SLIT2,RCHY1,MFAP3L,DTNA,DUSP9,FAM198B,FOXG1,DISC1,GPD2,CNTRL,GSN,ELOVL5,KCNMA1,BCO1,SERPINI1,NLE1,FSD1,MAPK8,PRPH,ZSCAN2,RAD52,ZDHHC14,TCP11L1,ZKSCAN3,KDM4C,ZC3H13,SPTAN1,LHPP,ST5,RGL1,TBCEL,ARHGEF12,TGFBR3,TMOD1,TRPC1,FLRT2,LMF1,ZBTB14,GDPD5,ITM2C,KAT6A" Drug 5780_DN Methantheline bromide [53-46-3]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "SEMA4G,MARCH3,CAMK2B,CDC42,RCBTB2,PLEKHB1,ZFYVE9,KIAA1549L,ARHGEF6,CDC42BPB,VCAN,GPRASP1,ARHGAP24,C2CD2L,DPH1,SORBS3,TNK2,ETV1,ZNF589,DENND2A,SEPT9,PCDH17,NF1,NFIX,PBX1,PIK3CD,NLE1,FSD1,MINDY2,PTN,TMEM231,SBF1,SEC14L1,ZNF821,GALNT10,SH3GL2,AMBRA1,ST6GAL1,SLC1A7,BTBD7,TROVE2,SYT1,MGRN1,KIAA0930,TIAM1,BHLHB9,LMF1,MAP3K12,HPS4,MVB12B,GAN" Drug 4123_DN Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "SRPX,AMH,SCAPER,CACNA1I,BTRC,ADGRG1,STOML1,FADS2,CRMP1,ARHGEF10,SDC3,RIMS2,RIMS3,DRD1,DTNA,EDNRA,SGK2,SUGP2,SORBS3,ING4,CAMSAP1,FHL1,TRMO,GAD1,DISC1,RUNDC3A,TDRKH,NR3C1,GRM8,KCND3,IPO5,MID1,ADAM22,NF1,PIK3CD,STRN3,POLG,PPP5C,PTHLH,FAM120C,SLN,ZCCHC24,IQSEC2,POPDC3,ATP11A,IQCE,PSD3,TNS2,TK2,ZNF45,MAP3K12" Drug 3180_DN Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "SERPINA3,TRMT9B,CDC42BPA,FAM131A,MARCH3,MARK4,ATP2A2,ATP6V0A1,CFLAR,SCAPER,CFAP410,PLEKHB1,TAOK2,BAG4,SDC3,CTIF,TOM1,EDNRA,EFNA3,SORBS3,CDKL3,ZNF44,GALC,ERAP1,POLL,GNG4,FERMT2,GRM1,HNMT,INPP5B,KCNF1,CAMKV,GON4L,TMEM104,PTPRG,RAB3A,RGS12,ROM1,RPS6KA2,SBF1,SLC1A7,SCMH1,WDTC1,SOX3,THSD1,ATP11A,EXOC7,TRIM2,TMOD1,VIPR2,SSPN" Drug 3985_DN Troleandomycin [2751-09-9]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ARID1A,TRMT9B,BIN1,ANK3,APP,ATP2A2,CHN2,B4GALT6,NMT2,RAB26,CREM,SH2B1,PARD6A,ATN1,MBNL2,IRAK4,MRNIP,LRRC23,FAM49B,MSL3,GUCY1A2,MUM1,KIF5C,LMO2,MN1,NFYA,PBX1,CDIP1,PPARA,SNRK,RIPOR1,RAB3IL1,RGS10,RXRA,ASAP3,NLGN1,SLC1A7,SLC6A9,SHANK2,ELMO2,RBM34,DDN,THSD1,SS18,ASTN2,ZKSCAN5,MICAL1,LMF1,REEP1,SH3GLB2,MPPE1" Drug 4091_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ADCY6,BIN1,CDC42BPA,SLC4A4,ALDH7A1,CFLAR,SYNJ2,ARHGEF7,CBFA2T2,HOMER3,CSF1,TENM4,EDRF1,RUSC2,ETV1,FGF1,FGFR1,CINP,ATP2C1,GLYR1,GPER1,GPR37,MAN1B1,BACH2,JAK2,KIFC3,GIT1,MYT1,NUMA1,CDK14,MINDY2,GON4L,RIPOR1,TMEM231,MYH14,FBXW7,SCN8A,DOCK10,FBXO11,SLC1A7,TROVE2,SS18,FAM168A,ASTN2,ZNF34,TK2,TNS1,RUNDC3B,HIRA,LAT2,XRCC4" Drug 2484_DN Terconazole [67915-31-5]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "BIN1,ARRB1,MARK4,SLC4A4,STX16,SLC16A4,TMEM184B,COL9A2,CREM,SH2B1,CX3CR1,ARHGAP32,RIMS3,HIPK3,FEM1B,CELSR3,EIF1,LRRC23,FGFR1,SEMA4D,EFCAB2,SEPT9,AHDC1,POLL,GPR19,SLC2A6,ATXN2L,TJAP1,ITGA7,MAP4,GIT1,NCAM1,PLCB2,PILRA,CNNM2,PTN,PTPRN2,RAB3A,RAD52,ZDHHC14,MYH14,SEC14L1,SH3BP2,EMC1,DBNDD2,WWC1,IQCE,TCF7L2,PARD3,PLPPR2,TIGD6" Drug 5091_DN Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "PPFIA3,MADD,KIF1A,ADGRB2,CACNA1A,SOCS6,CREM,ARHGAP24,SPOCK3,EDNRA,HIPK3,FCF1,ETV1,SCML2,IQCG,CSPG5,PNMA2,GAB1,ERAP1,DISC1,C1QL1,GPD2,TDRKH,GPR37,MATN3,NASP,NDP,NF1,NPR2,PPP3CC,MAPK3,PTN,PEX5,PID1,TTLL7,SBF1,ZFP30,FNDC3A,LIMS2,SLN,TNIK,CAMTA2,KIAA1107,TCF7L2,TNS2,PLPPR2,VGF,LMF1,ZNF24,NDRG4,SLC17A7" Drug 1747_DN Lobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "C1QTNF1,MAP4K3,APBA2,BTK,RUNX1T1,CD38,EPS15L1,CLTB,TJP2,DBN1,MBNL2,KIAA1109,SEC23B,ZNF44,NEU3,CRCP,GNG3,PRRC2B,DIDO1,ELOVL5,IDH3A,KTN1,MAP4,NF1,CNOT4,PDE3B,KCTD15,TRHDE,PPP2R5C,MAPK3,CNNM2,CHD9,WDR37,KBTBD4,EMC1,TSPYL2,TTBK2,AGTPBP1,DMXL2,TCF7L2,TRPS1,VGF,VIPR2,LAT2,XRCC4,REEP1,ZNF184,WIPF2,MPPE1,UBE3B,AAAS" Drug 1217_UP chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ALAD,APP,AQP4,PDE8B,ALDH4A1,CACNA1I,BTRC,CACNA2D1,DNAJB5,AKAP7,HAPLN1,PHF14,DAPK3,SPOCK3,TRAPPC9,DPH1,RCAN1,SGK2,EFNB3,EGFR,STX2,AFF2,NCKAP1,GART,ALDH1L1,GNAO1,STON1,SOX21,SHISAL1,ITIH2,MAP4,GIT1,ZNF862,NAP1L1,NF1,CNOT4,POLG,SH3TC2,RNASE1,NUDT11,RYR1,FNDC3A,SLC1A7,TSNAXIP1,ARHGAP26,NR2C2,TRIO,TRPC1,UGT8,XRCC4,SH3GLB2" Drug 3683_UP Nitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "NME5,BCAS1,ATP1A3,ADAM23,CACNA1I,CACNA1A,LDB2,CBFA2T2,CHRNB2,RAB26,DCT,APC2,HPCAL4,DCTN2,FOLR2,SORBS1,GAB1,ATP8A2,RUNDC3A,GNAL,GPD2,PRUNE2,GRIK2,GRM8,TLX1,ICA1,IGF1,MARK1,MSR1,LYRM9,MYT1,NNAT,PBX1,CDK18,PGAM2,PNMA3,PROX1,SUGCT,MYH14,RYR3,SOX15,HECW1,MLC1,TACR1,KAZN,PIK3R5,LAT2,SPHK2,SEMA3B,KCNAB1,NLRP3" Drug 3215_DN Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASPHD1,ASIC1,NDRG3,ADRA1D,AP2A2,PLA2G6,LTBP4,AMPD2,BIN1,CAMK2G,TAOK2,EPS15L1,FADS2,VAX2,HOMER3,WHRN,CTH,GPRASP1,MAML1,DAPK3,EDNRA,FEM1B,EIF4G2,EIF5,RASGRP2,MTSS1L,OGA,GABRA2,NR3C1,BTN2A1,MAP4,TM6SF1,KITLG,NFYA,PALM,PCDH9,RETREG1,STRN3,MAPK8,SAMD9,RGS12,COA1,KDM4B,SPART,TROVE2,ARHGEF9,PLCB1,ATP11A,TK2,PIK3R5,REEP1" Drug 5685_DN Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "BRAP,DGKD,ATM,EIF4G3,RIPK1,KIF1A,CFLAR,HIP1R,PLEKHB1,SLC4A8,BAG4,ABCG1,PDE4DIP,DZIP3,INTS1,ARNT2,FECH,BAIAP2,TRAF3IP2,GLYR1,CNTRL,RNFT2,INPP5B,KCNJ3,MAP4,ADAM22,PC,MINDY2,KLK6,RIPOR1,RAD51D,FOXRED2,AMBRA1,FBXO11,SPTAN1,ZBTB43,FCHO1,EXOC7,TCF7,TRIM2,ATP13A2,AP4E1,TPD52,HIRA,UBTF,LMF1,WNK1,MAP3K12,HPS4,MVB12B,KAT6A" Drug 1305_UP Carcinine [56897-53-1]; Up 200; 22uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "PPFIA4,NUMB,SYNJ1,SYNJ2,GYG2,MYRF,SLC25A14,CBFA2T2,AKAP6,SH2B1,CSF1R,FEZ1,MICAL2,VCAN,PPP1R16B,DOCK4,RUSC2,C2CD2L,DLG4,DTNA,SIDT2,EFNA3,ELAVL3,PCDH17,MSL3,GRIK5,IRF8,LSS,MEF2C,SLC11A2,PFKFB4,SLC25A23,MAPK7,BCAS3,PTAFR,RNASEL,ZNF671,MAP6D1,SLC1A7,FAM214B,SNCA,DOP1A,INKA2,CEP68,ARHGEF9,EXOC7,DMXL2,PSD3,ZNF384,TRPS1,BEST1" Drug 2880_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "TTYH1,PLA2G6,APOC1,ADAM23,GYG2,CAMK2B,CCNT1,CDH10,PICK1,CNTN1,CSNK1E,VCAN,RUSC2,TRAPPC9,ATN1,DTNB,ELN,HSD17B14,ERBB2,ERCC2,FGFR3,PDLIM5,GAP43,ALDH1L1,PCDH17,NR3C1,ICA1,ITGAM,NEUROD1,NUMA1,CDK18,TMOD2,SLC25A23,MAPK7,SNRK,RASA3,SLC11A1,SLN,SPTB,INKA2,MAPK8IP3,PHLDB1,JMJD6,VAMP1,ARC,ROBO3,DNMBP,SLC44A1,VSNL1,SYNC,GDPD5" Drug 825_DN rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ASPHD1,CLK4,C5,REPS2,TAOK2,LHX2,RAB28,HOMER3,AKAP12,RIMS3,LYPD1,PARD6A,TNK2,COQ7,DLC1,KAT8,POLR1B,FGFR3,CAMSAP1,FHL1,ANKFY1,NOP56,EFCAB2,PRRC2B,DHX35,PLEC,RETREG2,PPP3CC,APTX,PTPN13,TCP11L1,TRAPPC13,SFPQ,CHD9,WDR37,SLC6A8,SHANK2,ITPRID2,NCDN,ELOVL4,DIP2A,NSFL1C,JMJD6,TCF7L2,ARHGEF12,KAT6B,TPM1,ZKSCAN5,XRCC4,TFIP11,SEMA3B" Drug 1680_UP Panthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "CDC14B,ALDH4A1,SLC4A4,SYNJ1,CFAP410,RAB28,GPRASP1,JAKMIP2,HP1BP3,FBXL5,FGFR1,TXNL4A,GPER1,JAK2,VWA5A,KITLG,NF1,NFYA,PCDH9,CDK18,PLTP,PMP22,PPP2R2B,PPP5C,MAPK8,PRODH,PTPRE,CEP97,FAM184A,GTDC1,RGS10,EMID1,ASAP3,PREX2,PPP4R3A,SMARCD3,UNC5B,PLCB1,EXOC7,PCDHA6,ZNF34,PARD3,KAT6B,TRPC1,PDIA2,CLDND1,KCNK12,NDRG4,TFIP11,KAT6A,SENP7" Drug 2380_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.57E-04 1.00E+00 1.54E-03 1.75E-02 51 197 "ABAT,BEGAIN,SPTBN4,ARRB2,PDE8B,ADAM23,USP2,SEPT7,CDH8,TPP1,ENTPD4,CRMP1,DGKG,GSDME,SV2A,PIPOX,RRAGB,FHL1,HPCAL4,EFCAB2,PDLIM5,KHDRBS3,SIGLEC8,INPP5K,ICA1,KCNF1,KHK,SCAMP5,NAP1L2,NFIX,NRCAM,CCSER2,POU3F2,POU3F4,MINDY2,CNNM2,GALNT10,SNCA,RBM34,SOX10,RBM26,ATP10B,ROBO3,CAMSAP2,TCF7L2,PSD3,CRTC1,PCDHA5,SLC35G2,TEX15,SLC17A7" Drug CID000003121 valproate Stitch 1.58E-04 1.00E+00 1.54E-03 1.75E-02 87 381 "ABAT,SFMBT2,CFLAR,SGCE,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,NGB,CACNA2D2,ASIC3,QKI,CPS1,VCAN,HDAC9,HDAC4,CACNG7,TUBD1,GPHN,ADGRV1,CACNG2,TUBB3,TUBB4A,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,TUBA8,GLRB,TUBA1C,GRIA1,GRIK1,HBA1,TUBB2B,KCNH2,KCNQ3,MYCN,MYO6,NCAM1,PCDHGC3,ABCB1,PKD1,POLG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,RELN,PTCH1,RET,RYR1,RYR3,MAPK12,SCN4B,TRA2B,SLC1A2,SLC6A1,SLC6A11,SNCA,SNRPN,SCN3B,CUX2,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,TGFBR3,TRIO,TRPM2,TUBB1,TUBA1A,EPM2A,NETO1" Drug CID000002691 AC1L1E8W Stitch 1.60E-04 1.00E+00 1.57E-03 1.78E-02 32 107 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ALDH7A1,CACNA1E,SPAG9,LRBA,COX4I1,DMPK,DRD1,IRAK4,PPP1R1B,GFRA1,HPGDS,GRM5,KCNA6,KCNJ3,KCNJ5,MATN3,PDE4B,PDE4D,PRKACB,MAPK3,SLC6A1,TLR4,TPM3" Drug CID000024460 lead chromate Stitch 1.60E-04 1.00E+00 1.57E-03 1.78E-02 30 98 "ASIC1,NT5C3B,ATM,ALDH7A1,CFLAR,C5,CACNA1A,CACNA2D1,KRIT1,DBI,ERCC2,DNER,GFAP,CRCP,KCNMA1,MYL3,SLC11A2,KCNK10,PPP3CA,PPP3CC,PRKCB,PRKCG,PTK2,RAB3IL1,DPF2,COPZ1,RADIL,SLC11A1,CABIN1,SLC30A4" Drug CID000004584 AC1L1IHP Stitch 1.67E-04 1.00E+00 1.63E-03 1.85E-02 151 729 "AGT,PLA2G6,MYH7B,APP,CDK13,ALDH7A1,KIF1A,CFLAR,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,CAST,RUNX1T1,CCK,KRIT1,RGN,LRBA,CDC25B,CHRM1,RAB3C,SLC22A6,COG1,MYL6B,SLC4A7,CREM,NCOR1,CSNK1E,CSNK1G3,CALY,PPP6R2,DAPK3,B3GAT3,RASA4,TUBD1,SPEG,RPS6KC1,TUBB3,TUBB4A,PPP1R1B,ACTL6B,FOXO3,IQGAP2,INPP5K,CPLX2,GCK,TUBA8,MSTN,GFAP,CSDC2,KCNMB4,TUBA1C,GRIK1,NR3C1,GRM1,GRM5,KIF3A,TNFAIP8L3,CPT1C,HSP90AA1,MYLK2,IGF1,TUBB2B,KCNK3,KIF2A,KIF5A,KIFC3,ASPRV1,MAP2,MAPT,MBP,PPM1L,MYL3,NDUFA5,NEFM,NF1,NODAL,NPPA,PAH,PDE3A,PDE3B,PDPK1,CDK14,ABCB1,PHKG1,PIK3C2A,PIK3CD,PIK3R1,ZNF655,PLIN1,STRN3,MED1,PPM1B,PPP1R1A,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,PPP5C,PRKACB,PKIA,PRKCB,PRKCG,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,PSMD13,PTK2,PTPN13,PTPRD,PTPRN,PYGM,PPP2R3C,KIF7,GSTCD,RPS6KA2,MAPK12,SMPD3,KIF27,KIF21A,KIF16B,SLC12A4,KIF13A,SPP1,KIF1B,STAU1,SYN2,SYT1,LEFTY2,TK2,ACTR6,CABIN1,TSC2,TTPA,TUBB2A,TUBB1,UBTF,GORASP1,VLDLR,MAP3K12,TUBA1A,GOPC,NUP214" Drug CID000004425 EN-1530 Stitch 1.72E-04 1.00E+00 1.68E-03 1.91E-02 67 278 "ABAT,ACLY,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADRA1D,ADRA1B,ADRB2,AP1B1,AGT,CACNA2D1,CCK,CCKBR,CHRM1,CHRNA4,CHRNB2,SULT4A1,CNR1,DBI,DRD1,DMTN,PTK2B,ACTL6B,FOXM1,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PRLHR,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HRH3,KCNJ3,NOS1,NPY,OPRL1,PDYN,PENK,PRKCG,MAPK3,ASRGL1,SST,TAC1,TAC3,TACR1,ACTR6,TRH,NTSR2" Drug 3480_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.73E-04 1.00E+00 1.69E-03 1.92E-02 48 183 "SLC12A5,C1QTNF3,LTBP4,AMT,APAF1,GAS7,ARHGDIG,ALDH4A1,SYNJ1,CBFA2T2,ARHGEF2,RCBTB2,SRSF11,AKAP7,CTNND2,RIMS3,MAML1,GNE,SEZ6L2,SIDT2,MBNL2,ARMCX1,TESK2,BAIAP2,PDLIM5,STON1,GPER1,HMGCR,INPP5B,ARHGAP12,LSS,MMP16,ADAM22,ZNF862,PCDH9,MAPK7,C1orf54,CARF,ROBO1,PREX2,UHRF1BP1L,MAPK8IP3,PLCB1,TRIM2,PCDHA6,VLDLR,PRDM2,EVI5" Drug CID009543520 triphosphoinositide Stitch 1.74E-04 1.00E+00 1.70E-03 1.93E-02 66 273 "ASIC1,ANK1,DGKZ,DGKD,AQP6,PLA2G4C,BTK,WASF1,CALM1,DGKI,CDC42,ASIC3,CHRM1,HOMER3,SDC3,PLCXD3,USP6NL,DGKB,DGKG,EDN1,EGFR,EPB41,EPB41L1,EPB41L2,ERBB4,ACTL6B,SDCBP2,GAP43,GRK4,PLCD4,GSN,SCIN,KCNA1,KCNA2,KCNA4,KCNH2,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,KCNK2,KCNQ2,KCNQ3,OCRL,PIK3CD,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,PTK2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,ARFGAP1,SMARCA4,SCN3B,PLCB1,ACTR6,TRPC1,TRPC3" Drug CID000002124 aluminum fluoride Stitch 1.76E-04 1.00E+00 1.71E-03 1.95E-02 65 268 "ADCY5,ADCY6,ADCY8,ADRB2,MYH7B,PHF12,NT5C3B,ARHGDIA,ATP2A2,KIF1A,RGS9,ARHGEF25,CCK,AIFM1,CDC42,COPB2,CHRM1,CNOT8,CLTC,PLCXD3,WDR20,DNM1,DNM2,ABI1,DNM1L,BSCL2,PTK2B,FECH,ACTL6B,FOXM1,MSTN,GNAL,GNAO1,GNAS,GNG3,STON1,PLCD4,PTPN5,HP,HPR,KITLG,AFF1,AFDN,NODAL,OXTR,PDCD2,ABCB1,PLCB2,PLCD1,PRKCB,PRKCG,MASP1,PTK2,RGS3,RGS4,RGS7,PBRM1,CASC3,ARHGAP26,PLCB1,TBL1X,ACTR6,SLC26A10,SCG2,PLD4" Drug CID000002995 desipramine Stitch 1.76E-04 1.00E+00 1.71E-03 1.95E-02 49 188 "KCNH8,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,BSN,CHRM1,SLC32A1,DRD1,ZMYND10,GAP43,LOXL3,GRIK1,GRIN2D,NR3C1,CIT,HRH3,TNFAIP8L3,HNMT,HP,HPR,HTR2A,HTR5A,KCNN3,MAOB,MAP4,NPY,OPRL1,PDE4B,PDE4D,GLDN,AP1AR,SMPD3,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SLC22A4,SST,TRH,PLPPR5,SLC17A7,SLC17A6" Drug 2490_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.76E-04 1.00E+00 1.71E-03 1.95E-02 49 188 "NDRG2,ADRB2,PDXK,MARK4,ASPH,BCL7A,CFAP410,SLC16A4,RCBTB2,RAB33A,BAG4,CSNK1E,PPP1R16B,ZNF337,KIAA0586,DBT,ZNF804A,RUSC2,DTNA,EFNA3,LPAR6,ING4,NCALD,F5,KAT8,NCKAP1L,HMGCR,LSS,SCAMP5,N6AMT1,ZNF862,NFYA,SLC11A2,PFKFB3,PLCD1,PLEC,MAPK7,CNNM2,RBBP6,RGS10,SLC2A5,SLC6A8,BTBD7,SLC20A2,WDTC1,DDN,FAM168A,TCF7,KCTD2" Drug 1306_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.76E-04 1.00E+00 1.71E-03 1.95E-02 49 188 "ABHD6,NDRG2,APBB2,ARNTL,ADAM23,ST3GAL5,SCAPER,HIP1R,KYAT1,CLGN,ABCG1,FEZ1,PDE4DIP,SLITRK5,CX3CR1,DOCK4,RIMS3,DNAJC6,TUBD1,EPS8,EXTL2,PCYOX1,PDLIM5,SEPT9,WASF3,ADAM28,STON1,PCLO,PADI2,ITGA7,KIF5C,NCAM1,NRGN,SERPINE2,SERPINI1,PLCD1,RAB3A,SATB1,ITSN1,ANKRD6,PALLD,TNIK,RGL1,STXBP1,CAMSAP2,PSD3,ATP13A2,KCTD2,TRIM9" Drug 4209_UP Zardaverine [101975-10-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.76E-04 1.00E+00 1.71E-03 1.95E-02 49 188 "GRAMD1B,CDK13,ASCL1,N4BP2L1,CACNA2D1,HIP1R,MAP7,RUNX1T1,ARHGEF2,CHN2,FAM149A,WHRN,SLC4A8,GAL3ST1,CTH,CTNND2,PITPNC1,SRGAP3,ARNT2,ST8SIA3,HIPK3,PLXNC1,IRAK4,CORO2B,KAT8,GLI2,GRM2,HPSE2,HTR2A,ICA1,KCNJ5,MYH7,PDE4B,SERPINI1,SMOX,PRKAR1B,PKN2,MAPK7,WDR25,PTHLH,RASGRF1,CCDC102B,EMID1,ST8SIA1,NPAS3,SPART,MAPK8IP3,RPGRIP1L,SEZ6L" Drug 3002_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.76E-04 1.00E+00 1.71E-03 1.95E-02 49 188 "SYN3,GRAMD1B,ADORA3,RGS9,FGF17,NRP2,TMEM257,CDO1,CHN2,CNTFR,CTNND2,RIPOR2,RUSC2,EDN3,DMTN,STX2,FAM198B,ATP8A1,FER,AFF2,C1QL1,GPR22,GPR45,ATXN2L,KLF12,HPSE2,KIT,MAPT,MYO6,NPTX1,KCNK10,PDE1C,PFKFB4,BCAS3,FAM120C,RAB3IL1,BEND5,ZNF423,SYT1,ROBO3,ICAM5,TMOD1,TPM3,FLRT2,KCNK12,SPHK2,ZBTB16,NT5M,ACTR3B" Drug CID000002524 1-alpha-25-dihydroxycholecalciferol Stitch 1.77E-04 1.00E+00 1.71E-03 1.95E-02 183 909 "ABAT,FAM43B,ADRA1B,ADRB2,MTUS1,SPARCL1,AMH,ALS2,MARCH3,NCOA1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,RIPK1,BBS2,SCAPER,CA4,CA8,CA12,CACNA1D,CACNA2D1,CALB1,CALB2,CALM1,CH25H,CD86,SCARB1,CD38,DLGAP1,B4GALT6,CLU,STOML1,CNTFR,COL9A1,COL9A2,COL9A3,SLC4A7,NRG2,CP,PNKD,AKAP12,NCOR1,NCOR2,CSF1,CSF1R,PLCXD3,BOC,DOCK4,KIF26A,SIRPA,C8orf34,GSDME,FAM107B,PDCD6IP,ARRDC4,SEZ6L2,TSPAN5,EDNRA,KLHL5,EGFR,CALCRL,ENO2,ERBB4,ADGRV1,F3,FAM198B,TAOK3,ST3GAL6,FGF1,BAIAP2,AGAP2,AGAP3,ATP2C1,ZNF44,CAB39,DNER,MSTN,ADAM28,GFRA1,GFRA2,CSDC2,MALT1,GNAS,PLCD4,RFFL,NR3C1,GSTM5,GSTT2,HAS2,PADI2,TNFAIP8L3,IGF1,IL6ST,IL12A,ITGA7,ITGAM,CREG2,IPO5,LAMA2,LIFR,KITLG,MITF,MSR1,MYO5A,NCAM1,NELL2,NODAL,NPPA,NRGN,NTRK2,NTRK3,OLR1,OMG,OXTR,PBX1,PCSK5,PDE2A,PDE4B,ABCB1,SERPINE2,SSH1,PKM,PLCB2,PLCD1,STRN3,MED1,PTPA,PPP3CA,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,LAMA1,SNRK,PTHLH,PTH1R,PTPRO,PTPRZ1,MARCH1,RET,GSTCD,RXRA,RXRG,TMEM156,SAFB,SEMA6D,SEC14L1,SH3GL3,CHD9,SYBU,ST8SIA1,SLC20A2,SLCO1A2,LIMCH1,PALLD,TMCC1,KDM4B,PDZD2,SPP1,CAMTA2,SEPT8,PLCB1,SYT1,EHBP1,TCF12,LEFTY2,HHIP,ZFP91,TMOD1,KAT6B,TRH,CA14,TTPA,VSNL1,KCNT2,TUBA1A,SEMA3B,NAV3,WNK2,EPM2A,GOPC" Drug CID000003226 enflurane Stitch 1.78E-04 1.00E+00 1.71E-03 1.95E-02 23 68 "ADORA1,CACNA2D1,CRY2,EDN1,ATP2C1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIA1,GRIN2C,GRIN2D,KCNA1,NBL1,DDN,HEY1,TPM3" Drug ctd:D016578 Crack Cocaine CTD 1.78E-04 1.00E+00 1.71E-03 1.95E-02 23 68 "LDB2,CLTB,CTNND2,DYNC1I1,ENO2,ST3GAL6,GAD1,GAP43,GNAO1,GPM6A,GPM6B,GSN,TAGLN3,NEFM,PCSK2,PLP1,SEPT4,PRKCB,MAPK3,MAPK10,PTK2,PTN,UCHL1" Drug 6646_DN Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ARID1A,KIDINS220,APC,SCAPER,MYRF,MAP7,WHRN,CREM,VCAN,PDE4DIP,HDAC4,GIT2,SIRPA,RUSC2,KBTBD11,SIDT2,EFNA3,PLXNC1,COQ7,EZH1,EFEMP1,DENND2A,INPP5K,GRM8,MAN1B1,TJAP1,IL6ST,KIF5C,VWA5A,LSS,NF1,CCSER2,PPP5C,MAPK7,PTPRH,RAB3IL1,RAD51D,SH3TC2,SEC61A2,RPS6KA2,AMBRA1,SLC4A3,EPN2,TNIK,SPTAN1,SS18,SYT1,TMEM121,TFIP11,NAV3" Drug 4280_DN Tropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ACTN2,APOC1,SYNJ2,CAST,SPAG9,CHN2,AKAP7,ENTPD4,ARHGAP24,DTNA,FCF1,EN2,SEMA4D,FLT1,CINP,PRELID3A,INPP5K,SPIN1,TDRKH,RASSF8,IL6ST,ITIH2,KIF5C,TAGLN3,CLDN11,RETREG1,STRN3,SPATA6,MAPK7,GRAMD1C,ACSS3,RGS10,SLC25A36,CCDC88A,SNCA,KDM4C,MAPK8IP3,SYT1,ASTN2,TCF7L2,DICER1,GPR161,THRA,SF1,TFIP11,WNK1,PRDM2,EVI5,SEMA3B,KAT6A" Drug 3242_DN Carcinine [56897-53-1]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "AK2,PLA2G6,EPB41L5,GAS7,APOC1,ARRB1,ATM,KIF1A,MPDZ,CFLAR,SYNJ2,BTRC,SCARB1,UBE2L6,ZFYVE9,CSF1,CTH,PPP6R2,MAML1,DSCAM,EFNA3,SUGP2,F3,BAIAP2,OGA,GART,HNMT,TJAP1,KCNF1,MAP4,MPP2,PDE3B,PRKAR1B,PSMD13,RGS10,SLC25A36,NEK11,RPS6KA2,SBF1,ZFP30,ABLIM3,DOP1A,ZCCHC24,FBXW11,ARHGEF12,PARD3,ZMYND8,REEP1,SEMA3B,SSPN" Drug 1331_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "AP2A2,SLC4A4,BCL7A,CFLAR,CAPN3,CD86,CLCN3,SLC4A7,VCAN,DCAF8,TM9SF4,C2CD2L,RCAN1,EGR3,EPS8,F3,ANKFY1,ERAP1,INPP5K,VSIG4,IL6R,LIG4,MITF,CNOT4,NUCB1,OCRL,ENPP2,SERPINE2,PIK3R1,ZFYVE21,RETREG1,PLEC,SAMD9,SIDT1,SGK1,SLA,SLC6A8,RAB3GAP1,CCDC88A,SPP1,CDK19,SS18,VAMP1,UBE2H,PLPPR2,XRCC4,ZNF24,ATP6V0E2,LAMP5,HPS4" Drug 6512_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "LTBP4,BEGAIN,AMPH,APBB2,APOC1,ATP2B2,N4BP2L1,CAMK2B,CAMK2G,HIP1R,CBARP,WHRN,NCOR2,IPCEF1,GREB1,CYBB,DCC,RUSC2,SMG7,NTM,KBTBD11,DTNA,EFS,SCARA3,AGAP2,SIGLEC8,GLS,GNAS,PTPRT,RASSF8,KIF5A,MAN2A2,MATK,MBD1,NF1,NPPA,OPCML,RASGRF1,FBXW7,PPP1R9A,PPP4R3A,SLC6A9,PLCB1,EXOC7,SLC44A1,TK2,HIRA,NSD2,WNK1,NUP214" Drug 6783_DN Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ADCY6,ALCAM,APBB2,ARRB1,SYNJ2,SLIT2,PLAA,CRY2,FEZ1,CTNND2,MFAP3L,RABGAP1L,DMTF1,DTNA,FOXG1,CNTRL,INPP5B,KCNJ3,KHK,MAP4,MAPT,ADAM22,NAP1L1,CNOT4,PCDH9,MINDY2,PRPH,CLIP1,ZFP30,AMBRA1,NUBPL,ZNF365,SLC20A2,SMARCC2,WDTC1,ARHGAP26,SPART,ELOVL4,FAM168A,PLCB1,ARC,TNS2,CABIN1,TRPC1,HIRA,DNAJC12,LMF1,XRCC4,REEP1,SSPN" Drug 4180_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "DPF1,KLRC4,AGT,APBA2,ATP2B2,SLC2A11,ADAM15,MTMR3,BAIAP3,CACNG1,CALB1,USP2,ADGRG1,AKAP7,FAM149A,BAG4,MICAL2,DBT,DCC,HEPH,HP1BP3,DMPK,ING4,TNK2,MTSS1L,TUBB4A,FHL1,ZNF44,SIGLEC8,GFER,RUNDC3A,RND1,GRM7,SOX21,ADAM22,ZNF862,NCAM1,NEFM,NPR2,NTRK2,RAB3A,PID1,SLC11A1,SP4,ATP10B,TCF4,LAT2,ZNF711,SLC17A7,PHTF2" Drug 4253_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "PLA2G6,APBB2,APC,NRP2,BTRC,CFAP410,MAP7,DNAJB5,TENM4,PDE4DIP,EDRF1,PLPPR4,DTNA,EDN1,MBNL2,MTSS1L,ETV1,ANKFY1,AFF2,OGA,FYB1,ZNF44,RUNDC3A,GPR37,HSF2,ITPKA,LIG4,LSS,ADAM22,NOVA2,OPCML,PLXNB1,PPARA,PTPRB,GTDC1,ITSN1,FRMPD1,KANSL3,ELMO2,KIF13A,SS18,SYN2,TRIM2,CRTC1,TEX15,THRA,R3HDM1,SPHK2,REEP1,EVI5" Drug 3578_UP "(+,-)-Synephrine [94-07-5]; Up 200; 24uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ADORA2A,BIN1,AMT,KCNAB2,APLP1,ATP2B2,CACNA1I,CA4,CNTN1,WHRN,CREM,ATRNL1,RASSF2,CTIF,ATN1,RCAN1,DYRK1A,ELAVL3,DMTN,F5,AGAP2,GABRA2,GRIK1,GRM7,IL6ST,KCNJ3,LAMA2,NEFM,NF1,KCNK10,PDE4D,PLCB2,POU3F2,ELOVL2,PTPRO,RGS12,CPEB3,CNKSR2,FAM214B,SORCS3,MLC1,ARC,ROBO3,PSD3,SLC44A1,TIMP4,FLRT2,ZNF711,SLC30A3,NT5M" Drug 1768_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ACTN1,BRAP,APBB2,APP,ARNTL,ATM,SYNJ1,FUBP1,WASF1,KRIT1,CHRNB2,SLC4A7,ZNF337,DTNA,KCTD3,DENND4A,VPS26C,F3,ST3GAL6,SEC23B,GLS,KTN1,AFF1,NAP1L1,NUCB2,OPA1,PIK3C2A,ZNF426,TRHDE,STRN3,RETREG2,PPM1B,PTPA,CLIP1,ATXN7,FBXO11,WDR47,HECW1,RBM26,POGZ,ITPRID2,ERBIN,NXT2,CEP68,AGTPBP1,TCF7L2,WIPF1,EVI5,SNX27,RTN4" Drug 4846_UP Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ACTN2,KIAA1324,CDC42BPA,RGS20,ADAM23,ST3GAL5,CDC42,COL9A3,HAPLN1,ARHGEF10,DCAF4,NOS1AP,DAPK3,CTIF,ATN1,ELN,ST3GAL6,ZNF589,OLFM1,FLNC,NR3C1,ATXN2L,ITIH2,KCNB1,KCNMA1,MATK,MID1,TAGLN3,NNAT,NPTX1,ENPP2,PDYN,SMIM7,MTRF1L,PLPPR1,RGS4,NLGN1,SNCA,EMC1,COLGALT2,ZC4H2,MAPK8IP3,WSCD1,DOCK9,FAM189A1,TEX15,TNS1,PIK3R5,TRPC3,TIGD6" Drug 5020_UP Bretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "APC,APP,MARK4,ALDH4A1,N4BP2L1,RGS11,GYG2,CA4,FADS2,CNTN1,ELMO1,EXOG,DMPK,HIPK3,SIDT2,ING4,ERCC2,CDKL3,EZH1,KHDRBS3,GRK4,ATXN2L,KCNN1,KITLG,ADAM22,MX1,ZNF862,NF1,ODF2,PIK3CD,STRN3,MED1,MAPK8,MAPK10,PLPPR1,PTN,SYNDIG1,FOXRED2,SH3BP2,SLC1A7,FAM214B,SMARCD3,CDK19,TBCEL,SMG6,WSCD1,PCDHA6,SLC44A1,EMSY,SEMA3B" Drug 3773_DN PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ABR,ADCY6,APC,CDK13,BMP7,ST3GAL5,NEURL1,CHM,ZFYVE9,ABCG2,HOMER3,CRMP1,ZFYVE16,RIMS3,DAPK3,SGSM2,DTNA,SGK2,FCF1,FGFR1,FHL1,DCTN2,GPM6B,IL12A,INPP5B,PDE4D,CDK14,SERPINI1,POLG,BCAS3,RAD51D,SUSD4,FUZ,NLGN1,DZIP1,OGDHL,CAND2,PEG10,ATP10B,SYN2,TBCEL,SZT2,AHCYL2,TNS1,SSBP2,VGF,ZBTB14,EPM2A,TIGD6,RNF146" Drug 5268_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "APC,CDC14B,CDK13,BCL7A,KSR1,CAMK2B,USP2,SEPT7,CRMP1,SDC3,GREB1,SPOCK2,SMG7,TMCC2,ATN1,EDN3,ELAVL3,LRRC23,FAM198B,CORO2B,KIAA1109,FOXG1,NSG1,FYB1,GNAL,GPR22,ADAMTS13,GRIK5,GRM1,IRF8,KCNB1,MDM4,RETREG1,PRKAB2,PKN2,ZNF821,SH3BP2,PPP1R9A,RPH3A,SLC1A7,KIF21B,PHLDB1,TCF7L2,PCDHGA10,ARHGEF12,PIK3R5,VIPR2,WIPF1,SF1,KAT6A" Drug 6189_UP thioridazine hydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ARID1A,AP2A2,ANK3,FGD2,APBB2,PLA2G4C,SLC4A4,ATP6V0A1,BMP7,CFAP410,CA12,MAP7,CHN2,CHRNA4,CSF1,PDE4DIP,DCT,MBNL2,MRNIP,BAIAP2,CAP2,IQCG,GPR153,MYOZ2,PCLO,KHK,LAMA2,LSS,MYO7A,OPRL1,PCDHGC3,CCSER2,RETREG1,CEP41,GAL3ST4,ARHGEF10L,NEK11,PPM1E,SLC11A1,PALLD,SPP1,NFASC,TPM2,HIRA,LMF1,SLC30A3,PRDM10,PAK5,ADAMTSL3,SSPN" Drug 1227_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ASIC1,ARID1A,CDK10,ARNTL,N4BP2L1,SYNJ2,C5,IL33,NMT2,LY86,AKAP7,AKAP12,CRY2,ZFYVE16,EFNB3,CELSR3,IRAK4,TNK2,ZNF276,STON1,GRIK5,GUCY1B1,ITPKB,ZNF862,NPR2,PRKAR1B,PTAFR,MARCH1,RALGDS,C1orf54,TTLL7,ZFP30,SH3BP2,BTBD7,SMARCD3,SPATA7,SPTB,SS18,EXOC7,TCF7L2,TRIM2,SYNE1,CRTC1,TEX15,TPM2,LAMP5,EMSY,HPS4,PLSCR4,TIGD6" Drug 2675_DN prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "N4BP2L1,MPDZ,LDLRAD4,IQCK,ARMC8,RCHY1,MICAL2,SLITRK5,EDRF1,CX3CR1,TSPAN5,ELN,RASGRP2,MTSS1L,ZNF44,ERAP1,SEPT9,KCND3,KCNMA1,MGAT3,PDE4B,PRKCZ,SYTL2,SIDT1,PTAFR,RIPOR1,KHDRBS2,RGS3,PLPPR3,SCN2B,FRMPD1,FAM214B,BTBD7,SMARCA4,ARHGAP26,DDN,MAPK8IP3,CEP68,PDLIM2,KIAA0930,TCF7L2,SYNE1,THBS4,THRA,TNNT1,ZMYND8,UBTF,LMF1,CLIP2,NLRP3" Drug CID006857413 AC1OAGKW Stitch 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "DGKZ,DGKD,SYNJ1,SYNJ2,BTK,MTMR2,CCK,DGKI,CHRM1,CLTC,CSF1,PLCXD3,DGKB,DGKG,EDN1,EGFR,ERBB4,ACTL6B,FOXM1,FOXO3,GAB1,GSN,IGF1,KCNMA1,NCF2,OCRL,PDGFRA,PDPK1,SERPINE2,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PLCL1,PLTP,SH3KBP1,PKN2,PRKCZ,MAPK3,PTK2,SBF1,HSPA4L,SGK1,PLCB1,ACTR6,PIK3R5,TRH,PITPNB,LRP8" Drug 6162_DN Mesalamine [89-57-6]; Down 200; 26.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ABHD6,BRAP,MTUS1,PKP4,CAPN3,CDC27,SOCS6,FEZ1,PPP1R16B,DOCK4,DBT,RUSC2,DTNA,LPAR6,FHL1,FYB1,ERAP1,SEPT9,MAP4,NEK1,NFYA,SLC11A2,OGG1,OPA1,CDK14,CDIP1,MAPK3,SAMD9,TMEM260,TMEM156,SBF1,ATXN1,AMBRA1,BTBD7,COA1,ZHX3,TROVE2,VAMP1,ARHGEF9,DNMBP,TBL1X,TCF7L2,ARHGEF12,PARD3,TNS1,FLRT2,LAT2,ZNF24,KAT6A,ZNF248" Drug 6209_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ASPHD1,PKP4,APLP1,CDC14B,ATM,MAP7,USP2,CBFA2T2,NEURL1,PLAA,QKI,CREM,GIT2,DNM1,DTNA,APH1A,F3,ZNF589,FER,ATP2C1,PRELID3A,MALT1,COPS8,GNG4,GRB10,DHX35,IL6ST,ITPKB,MAP4,GON4L,RAD52,SH3BP2,BTBD7,ZBTB43,PHLDB1,VPS13A,TACC1,CHST8,AP4E1,ZNF34,KCTD2,ZNF384,TRPC1,ZMYND8,HIRA,BCL2L13,VIPR2,MICAL1,SEMA3B,MPPE1" Drug CID000004893 prazosin Stitch 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,CACNA1A,CACNA2D1,P2RX6,CBFA2T2,CHRM1,ABCG2,PLCXD3,DRD1,EDN1,EDNRA,LPAR4,PLCD4,HRH3,ATXN2L,TNFAIP8L3,HTR2A,HTR5A,KCNH2,MITF,BCO1,MT3,P2RY13,NOS1,NPY,NPPA,OPRL1,P2RX7,P2RY1,PENK,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,PLCB1,TRH,P2RY12,NETO1" Drug 7364_UP Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.78E-04 1.00E+00 1.71E-03 1.95E-02 50 193 "ADCY6,KCNAB2,MARK4,ASPH,ATM,SCAPER,REPS2,SOCS6,CNTFR,SLC4A8,DAPK3,SMG7,EDIL3,OPTN,ELN,ZNF391,ETV1,EZH1,FDFT1,TESK2,FGF13,ANKFY1,TRMO,GLYR1,PRUNE2,TDRKH,HMGCR,TJAP1,INPP5B,LMO2,KITLG,NF1,CLDN11,SERPINI1,PLCD1,PRPH,PTCH1,PTPRE,FAT4,ZDHHC14,ARHGEF10L,SNCA,KDM4B,SPTAN1,MAPK8IP3,VAMP1,ZKSCAN5,PDIA2,XRCC4,UBE3B" Drug 2182_UP Bromopride [4093-35-0]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,ADD2,SLC12A5,ADORA1,KIDINS220,SRPX,BIN1,APAF1,CDK10,ARHGDIG,HIP1R,DLGAP2,SLC24A2,STOML1,SIPA1L1,CTIF,MFAP3L,HS3ST2,EPHB1,REEP2,ATP8A1,FGF12,C1orf61,FYB1,DENND2A,GAP43,ALDH1L1,KCNMB4,ADAMTS13,GRM1,KIF3A,GSTM5,SOX21,NOVA2,NPPA,PDE4A,PFKFB4,GDAP1L1,PLEC,SLC25A23,PTPRN2,PID1,SEMA6D,CPEB3,SLN,TEX15,SEZ6L,VAV2,SLC13A3,ZIC3,NAV2" Drug 7509_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "PLA2G6,APC,PDE8B,MARK4,ADAM23,BAIAP3,MAP7,PLAA,ABCG2,CRY2,CSNK1E,CTH,SPOCK2,PITPNC1,SMG7,KBTBD11,FAM13A,COQ7,DMTN,LRRC23,FABP7,SYT17,GSN,HSD17B1,AFF1,MX1,ZNF862,CLDN11,PDGFRA,PFKFB2,CDIP1,FA2H,CNNM2,PTHLH,RAB3IL1,PID1,RAD51D,GSTCD,STUM,ZFP30,DOCK10,FNDC3A,RPH3A,UNC5B,INKA2,TBL1X,SMG6,OBSL1,DNAH7,TPM2,VIPR2" Drug 3323_UP Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,BRAP,AGT,NME5,BIN1,ATP1A3,CFAP410,ARHGEF1,CLGN,CRLF1,TAOK2,RAB33A,CLTB,DNAJB5,LY86,COL9A3,NECTIN3,DMPK,ATN1,ST8SIA3,CELSR3,PLXNC1,ELAVL3,ZNF589,FGF13,CAMSAP1,SIGLEC8,GFER,GRK4,KLF12,HPSE2,MARK1,ZNF862,NF1,NOVA2,KCNK10,SNTG1,PDE3B,CCDC40,ZDHHC14,TRIM68,KLHDC8A,ASIC4,SH3BP2,ST6GAL1,SLC9A5,SNCA,KDM4B,TAL1,PSD3,TRPM2" Drug 4221_UP Tolnaftate [2398-96-1]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "TTYH1,ABAT,KCNAB2,PPP4R4,ARSE,ASCL1,B3GALT2,BAIAP3,CAMK2A,SLC16A4,SYNGR3,NEURL1,DLGAP1,GPR37L1,ADGRG1,CHGA,TMEM59L,FAM149A,CX3CR1,DCC,TRAPPC9,DRP2,DTNA,RASGRP2,MTSS1L,ERBB4,AFF2,DPYSL4,SIGLEC8,NEU3,ADAM28,GLI2,GNAL,STMN2,KCNC1,SMAD9,MBNL1,ADAM22,MYH7,NTRK3,OPRL1,PPP1R1A,DCHS2,KLHDC8A,MAPK8IP3,ATP11A,TACR1,TRIM2,DOCK9,TEK,TRO" Drug 2749_DN Monocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RBM10,CDK10,ASPH,NCOA1,ATM,CFLAR,BMP7,MTMR2,CA4,SRSF11,FOXN3,CLCN3,FAM189A2,QKI,HOMER3,CREM,KIAA0586,MFAP3L,C2CD2L,TRAPPC9,DSCAM,EPB41L1,NCALD,ACSL4,ZNF589,SEMA4D,SRCAP,AHDC1,CACFD1,KHK,MITF,NFYA,SLC11A2,SETD4,SLC25A23,MAPK7,RGS10,SBF1,SCMH1,WDTC1,ZCCHC24,PLCB1,ZNF34,TMOD1,TSN,VGF,TFIP11,WNK1,MAP3K12,GDPD5,HPS4" Drug 6969_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "SLC12A5,AK2,FAM131A,SCAPER,CBFA2T2,CDH10,LHX2,QKI,ENTPD4,SIPA1L1,CYBB,MED12,CDON,ATN1,EDNRA,OPTN,AASS,ANKMY1,RRAGB,ZNF589,ANKFY1,AFF2,DPYSL4,GPR153,GAD1,SRCAP,GLYR1,GNG3,STON1,IL6ST,MAP4,MAPT,ADAM22,PPP2R2B,PTPRE,PTPRN,GTDC1,RFX3,RPS6KA2,EPN2,ZKSCAN3,SP2,IQSEC2,ASTN2,SEMA4A,WSCD1,SYNE1,RUNDC3B,SEMA3B,NAV2,GJC2" Drug 3044_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "APBB2,NCOA1,AZGP1,CFAP410,HIP1R,SLC16A4,CLGN,PLAA,CLCN4,TPP1,ZNF337,TM9SF4,ST8SIA3,HIPK3,SORBS3,ELAVL3,MTSS1L,DLC1,FHL1,EFCAB2,GCNT2,LILRA2,GSN,KLF12,TJAP1,NCAM1,PDE4D,LRRN3,RALGDS,ZDHHC14,ZNF821,SH3BGR,PPM1E,CCDC88A,TMCC1,WDTC1,CEP68,ATP11A,CAMSAP2,ADGRL3,KIAA1107,TCF7,TNS2,THBS4,KCTD2,RBFOX2,TRPS1,ZMYND8,SSBP2,PHTF2,SSPN" Drug 7048_DN GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASPH,SYNJ2,CACNA2D2,SOCS6,PLEKHB1,CHRNB2,NMT2,DNAJB5,SH2B1,FAM131B,TBC1D5,GIT2,EDIL3,SGK2,FHL1,ANKFY1,DENND2A,SYT17,GART,ARFIP1,GLYR1,MBNL1,MN1,PDE1C,PLEC,CDIP1,TMEM231,CEP97,FBXW7,CSRNP3,IL17RB,FAM102A,ST6GAL1,ELMO2,TMCC1,TNIK,PEG10,SPTAN1,RAP1GAP2,TROVE2,CEP68,FBXW11,TRIM2,SZT2,AHCYL2,DNAH7,RBFOX2,TRIO,MICAL1,UPF3A,AAAS" Drug 2369_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,NDRG2,PLA2G6,MRTFA,SEMA4G,PPP4R4,MARK4,KSR1,CDK5R1,ARHGEF7,MTMR3,FOXN3,CHN2,ZFYVE9,COL9A1,CREM,SH2B1,RCAN1,EDNRB,HEYL,COQ7,CDKL3,FHL1,PDLIM5,GABRA2,GAD2,WASF3,GLYR1,SPACA9,TJAP1,LAMA2,NNAT,PNMA3,CNNM2,RIPOR1,ZFP2,FRMPD1,RPH3A,CXXC4,ATP10B,WSCD1,DMXL2,DOCK9,TNS2,TEK,CDK20,TRO,ZNF32,SPHK2,WNK1,KCNAB1" Drug 642_DN 6-thioguanine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "AMPD3,EPB41L5,GAS7,PPFIA3,ARHGAP5,NCOA1,NAE1,BAIAP3,KALRN,RUNX1T1,KRIT1,NEURL1,ARHGAP33,NIPBL,IFFO1,OPTN,FAM13A,SUGP2,KCTD3,PLEKHA1,SRPK3,ETV1,NCKAP1,ALDH1L1,RNFT2,PAXBP1,MAP4,MATK,MBNL1,NELL2,NPR2,NPTX1,NTRK3,STRN3,MAPK3,STUM,SFPQ,SH3BP2,AMBRA1,MYCBP2,ZC3H13,SPART,PHLDB1,GANAB,KLHL7,SEMA4A,TCF7L2,ZMYND8,GDPD5,SLC17A7,GAN" Drug 221_DN 17-AAG; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADD2,BRAP,ALK,APBA2,ARNTL,PLA2G4C,CHN2,CLCN4,CLIP3,AATK,CSF1R,KLHL3,DMPK,DYNC1I1,EFNA3,EFNB3,FAM13A,EIF4G2,TNK2,ANKMY1,PTK2B,ZMYND10,FLNC,FYB1,GNAO1,SOX21,FAM107A,NXPH3,VSIG4,KCNJ3,MARK1,MMP16,NF1,NOVA2,PLCD1,MAPK3,RASGRF1,GAL3ST4,EMID1,SYNDIG1,SELL,LIMS2,SIRT2,SNCA,HECW1,SPART,TROVE2,ADGRL3,SEZ6L,ZNF32,HPS4" Drug 4485_DN Riboflavine [83-88-5]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "PLA2G6,ALK,AMT,APBB1,MARK4,ZBTB10,CDK5R1,BTRC,CLU,DNAJB5,WHRN,NRG2,AATK,VCAN,RUSC2,PARD6A,DTNA,SORBS3,PLEKHA1,RGS17,COQ7,DMTN,CDKL3,SCML2,FGFR1,IQCG,FAM49B,POLL,MUM1,SHISAL1,SCIN,KIF2A,MAPT,PRKAR1B,RIPOR1,FAT4,RAP1GAP,GAL3ST4,ASAP3,SLC4A3,PPP4R3A,ZNF667,KDM4C,VPS13A,KAZN,SYNE1,AHCYL2,TEX15,ZNF24,NDRG4,MAP3K12" Drug 2279_DN Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ARID1A,NME5,MRTFA,AMT,PLA2G4C,DNAH17,MARK4,CFLAR,BTRC,HAP1,AP4M1,HOMER3,CNTN1,SH2B1,CRY2,EDRF1,HP1BP3,PARD6A,ATN1,NCALD,KIAA1109,CAMSAP1,FHL1,AGAP2,SRCAP,POLL,CNTRL,LMO2,MAP4,MATK,ZNF862,MYT1,CDK18,PIK3CD,PLCD1,RAB3IL1,SH3BP2,ABLIM3,ZNF365,SLC20A2,EMC1,INKA2,VPS13A,PLCB1,SYN2,TCF7L2,THRA,TK2,ZMYND8,LAT2,SSPN" Drug 4246_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NME5,SEMA7A,APBB1,KCNAB2,PPP4R4,ZSCAN18,ATP2B3,NOL4,SYNJ1,CBS,ARHGAP22,ZFYVE9,SUSD5,SEC14L5,PYGO1,RIPOR2,MFAP3L,EXOG,DTNB,FGF1,DCTN2,PDLIM5,PCDH17,GNAO1,GPR22,GRIK1,ADAMTS13,HTR2A,ITIH2,VWA5A,NF1,NOS1,NPR2,NPTX1,MAPK8,PTPRN2,C1orf54,GAL3ST4,RGS4,MYH14,KCNIP1,SALL1,SCN3A,SH3BP2,SLC2A5,OGDHL,IZUMO4,KCNK12,XRCC4,ZNF225,NT5M" Drug 4134_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ACTN2,AK2,LTBP4,RASL11B,ATP1A2,GYG2,CACNG1,RUNX1T1,CHRNB2,ZFYVE9,CRY2,NCOR2,CSF1,CNTNAP2,DAPK3,SRGAP3,ATN1,RCAN2,GRM1,ATXN2L,ACOT7,KCNMA1,KCNN1,MMP17,CD200,ADAM22,NF1,OGG1,PAX6,PCDH8,CDK18,GPR85,CEP41,MAPK7,GDPD2,RAB3IL1,RGS10,SYNDIG1,SH3BP2,LIMCH1,ATP10B,PHLDB1,KIAA1107,WSCD1,SZT2,TMOD1,SEZ6L,TPM2,TRPC3,SLC30A3,SSPN" Drug 6248_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,SYT13,MRTFA,BIN1,AMT,ANK1,SEMA4G,SLC4A4,CFLAR,MTMR2,HAP1,CAMK2B,NEURL1,CRLF1,CNTNAP2,CTIF,MYEF2,TMCC2,DLG3,EFNB3,AASS,ING4,EPB41L1,EFCAB2,USP19,ADAMTS13,ATXN2L,MAP4,NDUFA5,NPR2,PPP5C,MAPK8,CEP97,TMEM206,SGK1,SLC15A2,FAIM2,SPTAN1,SEMA4A,EXOC7,PCDHA5,TEX15,THRA,UBE3A,VIPR2,ZFP37,SPHK2,NT5M,EVI5,KCNAB1,FAM13C" Drug 4131_UP Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,PLA2G6,ALCAM,AMPD3,ASPH,CADM3,N4BP2L1,SCAPER,SLC16A4,CHRNB2,RAB33A,WHRN,VCAN,NTM,EXOG,DYRK1A,EFNB3,STX2,NRN1,KIAA1109,GAD1,GPER1,KLF12,ICA1,KCNH2,KCNJ3,VWA5A,MAPT,ADAM22,NCAM1,NPR2,OMG,PDE3B,LRP12,LRRN3,KCTD17,SCN8A,STUM,SH3BP2,SH3GL3,FBXO11,SLC2A5,ARHGEF40,SLCO1A2,COLGALT2,KIAA1107,DMXL2,TCF7,TRPC1,ITM2C,PARP11" Drug 5688_DN Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "AMT,PPFIA3,ARRB1,CFLAR,KYAT1,SCARB1,BAG4,ENTPD4,PDE4DIP,DZIP3,GIT2,MED24,RHOBTB1,RBM12,BAIAP2,CNTRL,RNFT2,HNMT,MAPT,GIT1,ADAM22,NEK1,SLC11A2,NUMA1,OPA1,SLC25A23,PRODH,PRPH,WDR25,PSMD13,PTPRE,SUSD4,CCDC25,RXRA,LIMCH1,SPATA7,ERC1,ELOVL4,VPS13A,ATP11A,TCF7,AP4E1,SLC44A1,TPD52,TPM1,ZMYND8,UBE2H,VGF,REEP1,PCBP4,MPPE1" Drug 3756_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "PLA2G6,PKP4,APAF1,KCNAB2,FUBP1,CFAP410,CACNA1A,CAMK2B,SYNGR3,LRIG1,ARHGAP24,DTNA,EFNA3,LRRC23,NCALD,OLFM1,FGF12,BAIAP2,FGR,HPCAL4,DKK3,GALC,GNG4,ATF7,GRM7,GRM8,PADI2,IRF8,KCNH2,KCNQ3,MYL3,NPTX1,NPTX2,NRCAM,PCDHGC3,PCSK5,PRKCB,PTN,PTPRH,PBRM1,CSRNP3,CNKSR2,PREX2,ARHGEF40,AJAP1,SYT11,COBL,AP4E1,CA14,CADM1,JPH3" Drug 5798_UP Sulfamethizole [144-82-1]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "DPF1,NME5,PLA2G6,ADGRF5,GAS7,KIF1A,CAMK2B,FOXN3,CHI3L2,CHRNB2,SLC22A6,NRXN3,CNR1,IQCK,WHRN,CHRDL1,DTNA,EDIL3,EGFR,ERBB4,ZNF391,REEP2,CORO2B,CAMSAP1,DCTN2,PRELID3A,GRIK5,HMX1,HSD17B1,IL12A,KCND3,AFF1,ADAM22,PCDH9,PDE4D,PDYN,PRKCB,ZSCAN32,PTPRN2,RGS12,RASA3,CXXC4,ZHX3,MCF2L,TBCEL,TEX15,TRIO,ZMYND8,ZIC3,SPHK2,KCNAB1" Drug 4962_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "SERPINA3,AMT,APC,PPFIA3,APP,CDC14B,CFLAR,BTRC,SCARB1,CDC27,B4GALT6,PLAA,QKI,HINFP,GIT2,DTNA,TOM1,CDKL3,CAMSAP1,GALC,INPP5K,SRCAP,CACFD1,ITPKB,KCNK1,IPO5,MAP4,MAPT,KITLG,NF1,NRGN,KCTD15,PLCD1,PLEC,SLC25A23,LRP12,TMEM104,PLEKHB2,RAD51D,ARID4A,ELMO2,BTBD7,LIMCH1,CEP68,VPS13A,TCF7,TCF7L2,ATP13A2,PLPPR2,TFIP11,MVB12B" Drug 5875_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,SYN3,GRAMD1B,ADRA1D,AGT,APAF1,APC,ARRB2,PDE8B,ASPH,RGS11,NRP2,SYNJ1,BAIAP3,CACNA1A,KALRN,ZFYVE9,LY86,RAB26,SPOCK2,AASS,OGA,GFER,USP19,PCDH17,GPD2,KCNMA1,PLCD1,SMOX,PPP1R1A,PRKAR1B,ASAP3,FAM214B,IFT122,HECW1,ARHGAP26,DDN,CAMTA2,PLCB1,SYT1,TMEM121,TK2,SEZ6L,CADM1,AMOT,VAV1,VAV2,WNK1,ADAMTS9,HPS4,KCNAB1" Drug 4598_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADD2,C1QTNF3,MRTFA,APBB1,ARRB1,ST3GAL5,FUBP1,MYRF,SLC16A4,ARHGEF2,CHN2,SULT4A1,NRG2,CREM,CREB5,ABCG1,SUSD5,PHF14,ARHGEF4,CTNND2,RIMS2,AK5,RABGAP1L,ATN1,SEMA3D,PLXNC1,ERBB4,NCALD,C2orf72,IGF1,IL12A,MAOB,MMP16,NPR2,PCDH9,PDGFRA,BCAS3,CCDC40,C1orf54,RGS3,FBXW7,ATXN7,NLGN1,DHX30,SMARCA4,TSNAXIP1,IZUMO4,CDK19,PCDHA5,NUP214,GAN" Drug 4496_UP Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADORA3,AMPD3,SEMA7A,PPP4R4,CDK13,ATM,ATP1A3,ATP2B2,GYG2,CHRNA4,CHRNB2,STOML1,LRIG1,PDE4DIP,SPOCK2,C2CD2L,CHRDL1,DMPK,DUSP9,EFNA3,EPHA5,PRELID3A,GATM,RND1,PRUNE2,CNTRL,ADAMTS13,GRIN1,IGFBP1,IL6ST,FXYD7,OMG,EPN1,VPS13C,PTPRH,TMEM231,RGS4,RLBP1,KIRREL1,KCNIP1,DOCK10,BCAN,DOK5,EXOC7,TBL1X,SMG6,PCDHGA10,AP4E1,HIRA,WIPF1,SPHK2" Drug 7428_DN Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "FAM131A,APOC1,BCAS1,APP,CDC14B,ASPH,CFLAR,PLEKHB1,STOML1,HOMER3,AKAP7,PDE4DIP,MED12,DTNA,FEM1B,TNK2,KAT8,FGFR1,CGREF1,GPR153,CSPG5,OGA,GLS,CNTRL,ATXN2L,LSS,MEIS2,NF1,PC,PDE3B,PRKAR1B,TMEM104,TMEM231,RAB3IL1,RGS10,ITSN1,FERMT1,ABLIM3,SLC6A8,SIRT2,ZKSCAN3,WDTC1,FCHO1,PHLDB1,MCF2L,PLPPR2,ZNF45,ZNF74,EMSY,KAT6A,GAN" Drug 1648_UP nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,C1QTNF1,DOC2A,TRMT9B,ANK3,FAM131A,MARK4,CAPRIN2,SLC4A4,CADM3,BACH1,CFLAR,CDK5R1,CA12,CNOT8,HOMER3,NCOR1,MFAP3L,HP1BP3,LYPD1,ATN1,TSPAN5,MBNL2,LRRC23,F3,ZNF589,FAM49B,TXNL4A,MSL3,MAP4K5,VWA5A,MOBP,GIT1,LYRM9,SLCO1C1,PALM,LRRN3,PTCH1,ZSCAN2,CCDC25,UEVLD,TCP11L1,RASA3,SH3BP2,PPP4R3A,UNC5B,KAZN,RBFOX2,VIPR2,CLIP2,SSPN" Drug 5110_DN Aztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "MTUS1,ALAD,ARRB2,ASPH,STX16,ALDH7A1,FUBP1,BTRC,SCARB1,SOCS6,QKI,ARMC8,CREM,VCAN,ARHGAP24,DAPK3,EDIL3,FCF1,EFNA3,EGFR,MBNL2,EML1,STX2,ANKMY1,GART,GCNT2,PCLO,AGFG1,SCIN,KCNN1,NFIX,NUMA1,PPP3CC,RAD52,SH3TC2,SUGCT,KIRREL1,CSRNP3,FNDC3A,SLN,SNCA,ZNF415,PHLDB1,EXOC7,WWC1,PSD3,TMPO,VGF,ZNF711,EVI5,SMIM8" Drug 2066_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,APBB1,SEMA4G,MARCH3,SLC4A4,ATP2B2,ADGRB2,CACNA2D2,FOXN3,CHN2,DNAJB5,COL9A2,CRY2,CSF1,CNTNAP2,DCAF4,EGFR,COQ7,HPCAL4,GCNT2,POLL,GNG4,LPAR4,GRIK2,CACFD1,HSF2,KIFC3,MEF2C,NPPA,PCDH9,PDE1C,RETREG1,MAPK7,MAPK8,PLPPR1,IL17RB,ZNF821,STUM,SLN,IFT122,SNCA,UNC5B,SPTB,NCDN,TCF4,ZNF34,WIPF1,NSD2,HPS4,PLSCR4,RNF146" Drug 3909_UP CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "DPF1,FZD9,APAF1,APBA2,KCNAB2,AQP4,ATP1A3,USP2,CDC42,CLTB,CNTN1,AKAP7,AKAP6,CABP1,NCOR2,CYBB,SNPH,DCT,RABGAP1L,TMCC2,ST8SIA3,EDNRA,FRY,ELAVL3,KCNMB2,SPEG,FGFR1,ALDH1L1,GNAO1,GPM6A,GRM1,KLF12,SYNPO,C2orf72,KCNN1,MYO7A,PLTP,PTAFR,RFX3,RGS12,RPS6KA2,KDM4B,SOX2,CAND2,UNC5B,ACSBG1,VAMP1,DOCK9,PCDHA5,TNFRSF1B,ZFP37" Drug 5246_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "PLA2G6,SEMA6A,ALCAM,AMT,APC,ASPH,NCOA1,ADAM15,SYNJ2,MTMR2,ARHGAP33,CLGN,TAOK2,QKI,ARHGEF4,SMG7,EDNRA,EGFR,ING4,EPB41L2,STX2,KIAA1109,BAIAP2,CINP,PDLIM5,INPP5K,SRCAP,GPER1,KCNH2,LMO2,NDUFA5,MBOAT7,GON4L,RAD52,SEC61A2,ZFHX4,CLIP1,EPN2,SLC6A8,LIMCH1,ZCCHC24,ZHX3,UHRF1BP1L,THSD1,PCDHA5,ZNF34,TMOD1,PLPPR2,VGF,ZIC3,MPPE1" Drug 4352_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BIN1,CDC42BPA,ASCL1,N4BP2L1,RGS9,SYNJ2,CACNG1,CAMK2B,USP2,P2RX6,CBARP,SLC24A2,SULT4A1,IFFO1,CRMP1,RIMS2,DAPK1,CTIF,RUSC2,ST8SIA3,EDN1,EDN3,SIDT2,KCNMB2,CORO2B,FHL1,SORBS1,GPM6A,GRM2,GRM7,GRM8,GUCY1A2,ELOVL5,AFF1,ADAM22,MYH6,NOVA2,NTRK2,CDK18,POU6F1,DCHS2,RELN,KLHDC8A,SLC1A7,SLC12A4,PEG10,SPTB,AJAP1,VAMP1,ICAM5,SLC30A3" Drug 2128_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ALK,BEGAIN,SEMA4G,SCAPER,TAOK2,CRMP1,ABCG1,CSF1R,DCAF4,DAPK3,SMG7,MED12,FCF1,SUGP2,C3orf18,FAM49B,B4GALNT1,DISC1,GBX2,C1QL1,TDRKH,MAP4K5,TJAP1,IPO5,MAPT,MEF2C,MMP16,GIT1,ZNF862,PCBP3,PDGFRA,PRPH,RALGDS,SH3TC2,RGS4,MAPK12,ATXN7,DZIP1,ZKSCAN3,TNIK,SPTAN1,MAPK8IP3,COBL,TBL1X,SYNE1,CABIN1,TRPC1,HIRA,UCHL1,SF1,EVI5" Drug 4782_UP "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "DPF1,AMH,CDC42BPA,APBA2,KCNAB2,CDK10,PPP4R4,BRINP2,CFLAR,BTRC,VAX2,AKAP6,COL9A3,SEC31B,RIMS2,DBN1,SMG7,SGK2,STX2,ZNF589,HPCAL4,AGAP2,GPR153,GALC,C1QL1,GRB10,VSIG4,INPP1,ITIH2,KIT,MAPT,MEF2C,MSR1,NF1,NPTX2,NLE1,LRP12,MBOAT7,MED1,C1orf54,FBXW7,KCNIP1,ASAP3,SLC1A3,TBCEL,IQCE,ZEB1,CRTC1,PCDHA6,ZIC3,GDPD5" Drug 1593_UP Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; HL60; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ALAD,SYNJ2,CD86,CHRNB2,SLC24A2,CSF3R,PPP1R16B,TRAPPC9,DNM2,DPH1,SIDT2,EGR3,PLEKHO1,EZH1,F8,FCGRT,BAIAP2,FLNC,ZNF44,GAP43,ALDH1L1,GNAS,CACFD1,MAP4K5,SMAP1,LSS,SETD4,PDE3B,CAMKV,PIK3CD,SMIM7,MAPK10,CNNM2,GON4L,RAP1GAP,ARID4A,RFX5,RNASE1,BCAN,LIMS2,FAM214B,SLC6A8,SLC11A1,THSD1,TACC1,TK2,ZKSCAN5,STMN4,SLC17A7,MPPE1,RNF170" Drug 6037_DN Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADRA1D,PLA2G6,ALCAM,CDC42BPA,APC,EPB41L5,FAM131A,RGS20,ATP2A2,CACNA1I,CACNA1D,CAMK2B,CDH10,FOXN3,SLIT2,PDE4DIP,GREB1,MFAP3L,EDNRA,EDNRB,OPTN,PLXNC1,FGFR1,AGAP2,FYB1,GAB1,GAD2,GRIK5,ELOVL5,KCNN2,MDM4,MGAT3,KITLG,MMP16,MSI1,ZNF862,LRP12,RAD52,ZFHX4,SBF1,ZNF821,SLN,ZCCHC24,RPGRIP1L,SZT2,PCDHA5,CHST8,WIPF1,REEP1,HPS4,MPPE1" Drug 3003_DN Reserpine [50-55-5]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,ALAD,MRTFA,N4BP2L1,SYNJ2,SLC16A4,ENTPD6,FOXN3,SLC4A7,RCHY1,PDE4DIP,SLITRK5,RUBCN,KIAA0586,DAPK3,SMG7,TOM1,HIPK3,MBNL2,PLXNC1,MTSS1L,ZNF589,FGFR1,EFCAB2,GAB1,SEPT9,ITGAM,MGAT3,STRN3,MINDY2,PKN2,ZSCAN32,PTPRO,ARHGEF10L,GALNT10,NLGN1,BTBD7,ZHX3,KIF1B,CDK19,TROVE2,SYT5,ATP11A,CAMSAP2,TCF4,SLC44A1,TPM1,SMUG1,LMF1,LAT2,PHTF2" Drug 7221_UP Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "PLA2G4C,ALDH7A1,SCAPER,CA4,CCK,CD86,ARHGEF2,CREB5,SDC3,DCAF4,DCC,DRP2,SORBS3,ANKMY1,CAMSAP1,GAB1,GABRA5,GAD1,POLL,GRM1,GRM8,KLF12,HNMT,KCNB1,KCNJ5,MDM4,KITLG,AFDN,MSI1,NEFM,NF1,P2RY1,PCSK5,PROX1,KHDRBS2,RGS12,SCN2B,SLC1A7,FAM214B,SLC6A9,SLC11A1,BTBD7,SNAP25,IZUMO4,KDM4C,VAMP1,TACR1,SLC44A1,TRPC3,SLC13A3,SSPN" Drug 7433_UP Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ADD3,AK2,SRPX,MARCH3,SLC4A4,ADAM15,MPDZ,SCAPER,GYG2,CACNA1D,NRG2,AKAP12,FEZ1,DZIP3,NR1D2,DMTF1,HIPK3,MRNIP,VPS26C,TUBB4A,GAD1,SYT17,INPP5K,GFER,MALT1,TXNL4A,RNFT2,ARHGAP19,INPP1,LIG4,MBOAT7,PRKCB,PRPH,RALGDS,SH3BGR,KANSL3,SLC6A8,SLC6A9,CCDC88A,WDTC1,ZCCHC24,ATP10B,ATP11A,ANKRD12,EXOC7,CDK20,TRPC1,VLDLR,LMF1,RNF170" Drug 6160_UP Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BIN1,PRX,ATP6V0A1,ADGRB1,CACNB4,CALB1,SOCS6,CHRNB2,DNAJB5,CREM,PDE4DIP,DZIP3,DGKG,SPOCK2,CNIH3,PLPPR4,DTNA,OPTN,ING4,RASGRP2,ERBB2,CEND1,KAT8,CAP2,AGAP2,TRAF3IP2,MSR1,MYO7A,NTRK2,DUSP26,PRPH,MASP1,PTAFR,FBXW7,HSPA4L,FERMT1,PALLD,TMCC1,SPTAN1,IQSEC2,PHLDB1,FAM168A,TCF4,DMXL2,CRTC1,ATP13A2,SPX,SH3GLB2,SLC17A7,KCNAB1,NUP214" Drug 1924_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ANK2,NRP2,CFLAR,CBR1,CDH2,FADS2,ARHGEF10,ARHGAP32,DCTN1,HP1BP3,KLHL3,TNK2,COQ7,ERCC2,VPS26C,CAMSAP1,GAA,TRAF3IP2,DENND2A,GFER,PCDH17,PRRC2B,TJAP1,MAP4,MYL3,NF1,NPY,NLE1,PLCD1,PLEC,MBOAT7,CYBC1,RAB3A,ARHGEF10L,NUDT11,RXRA,SEC14L1,KBTBD4,SMARCA4,SRPK2,SYT1,EXOC7,WSCD1,KIAA0930,HEY1,KCTD2,PLPPR2,KCNAB1,ITM2C,AAAS" Drug 1919_DN Tolnaftate [2398-96-1]; Down 200; 13uM; PC3; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "APAF1,APC,GAS7,NCOA1,ATP2B1,BACH1,KRIT1,CCNT1,FOXN3,CLCN3,QKI,AKAP12,NCOR1,CSNK1G3,CTH,HDAC9,ZNF337,DNAJC6,G3BP2,EZH1,ACSL4,AMOTL2,CAMSAP1,SEC23B,MPP6,TRAF3IP2,NCKAP1,GART,CRCP,GNG3,GPR12,GRIK5,NR3C1,KTN1,CDK14,CYBC1,TMEM231,MYH14,TCP11L1,SH3BP2,SH3GL3,R3HDM2,SHANK2,KBTBD4,SLC22A4,VAMP1,SYT1,CLASP1,KLC2,SPHK2,ZNF189" Drug 6498_DN Protriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,BIN1,EPB41L5,APLP1,APP,PDE8B,MARK4,GYG2,C5,CACNG1,CAMK2G,MAGI1,CACNA2D2,B4GALT6,AATK,SDC3,ARHGAP24,DAPK3,DBN1,MFAP3L,DTNA,MTSS1L,KAT8,SRCAP,ELOVL5,HSD17B1,INPP5B,IPO5,MAPT,MITF,MPP2,N6AMT1,PCDH9,POLG,RAB3IL1,CCDC25,EMID1,ABLIM3,SMTN,PKNOX2,CXXC4,LIMCH1,TSPYL2,TROVE2,SS18,CEP68,NSFL1C,FAM168A,EXOC7,FBXW11,PSD3" Drug 2255_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADD2,AK2,ALCAM,BBOX1,APC,ASTN1,ATM,N4BP2L1,ADGRB3,CFLAR,KSR1,GYG2,BAIAP3,CFAP410,TAOK2,VCAN,SDC3,MYEF2,DMPK,SHANK1,ST8SIA3,HIPK3,TENM1,EPHB1,SCARA3,CSDC2,HPGDS,GLS,GRM8,TJAP1,MYO7A,CNOT4,CDK14,MTRF1L,PURG,MINDY2,LRRN3,RAD52,SCN2B,FRMPD1,ASAP3,SLA,SLC1A2,RPH3A,SHANK2,SOX2,SZT2,TK2,RIMBP2,PRMT8,SLC17A7" Drug 1391_UP Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,SYT13,APAF1,APBA2,GAS7,SHROOM2,NUMB,CADM3,BMP7,EPS15L1,SLC4A7,CRY2,HINFP,NCOR1,ARHGAP32,ZEB2,C2CD2L,TMCC2,CEND1,RUNDC3A,ADAMTS13,CACFD1,PADI2,KCNH2,IPO5,GIT1,NTRK3,SERPINE2,PLCB2,FTO,SLC25A23,PRPH,PTN,RET,RGS12,EXD2,TCP11L1,ZFP30,ITSN1,HECW1,DBNDD2,FCHO1,STXBP1,SYT11,DDHD2,OBSL1,TK2,PARD3,SEZ6L,TPM3,URM1" Drug 607_DN butein; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RBM10,ALAD,ANK2,GAS7,AQP6,CDK10,ASCL1,TBRG4,SLIT2,HINFP,AATK,PDE4DIP,RABGAP1L,DRP2,EFNB3,MRNIP,SRPK3,OLFM1,FGFR3,C1orf61,MALT1,RUNDC3A,GNG4,BTN2A1,IGF1,BRINP3,KHK,SMAD1,MMP17,GIT1,ADAM22,TREM2,PMS2,MAPK8,RGS12,TMEM206,TCP11L1,KBTBD4,SMARCA4,IGSF9B,PEG10,ATP10B,TROVE2,SEPT8,ANKRD12,THRA,KCTD2,ZMYND8,WNT7A,SLC17A7,NUP214" Drug 1942_UP Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,ADORA1,AGT,APBB2,ASCL1,PDE8B,CACNA1A,CALB2,KRIT1,CDH8,CACNA2D2,CHRNB2,CNTFR,SH2B1,EFNB3,SUGP2,TNK2,SRPK3,SEC23B,GAP43,CRCP,DIDO1,SPACA9,CACFD1,NCKAP1L,SYNPO,TJAP1,GIT1,MYT1,NTRK2,DUSP26,CAMKV,PRRX1,PACSIN1,PPARA,PPP5C,APTX,PTH1R,RNASE1,SYNDIG1,RXRA,BCAN,LIMS2,SNAP25,ZC3H13,PHLDB1,SYN2,ZKSCAN5,VGF,VIPR2,ZNF24" Drug 3739_UP Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,ASPHD1,LTBP4,APAF1,DNAH17,KSR1,CA12,CACNG1,TAOK2,RAB33A,CLCN4,FAM149A,AKAP5,CREM,CSF1R,ERC2,ARNT2,HS3ST2,TRAPPC9,DSCAM,DTNA,EFNB3,NCALD,AGAP2,FYB1,GNAL,GPR19,GRIK3,SOX21,TJAP1,ITGA7,KCNN1,LIG4,NDUFA5,OPRL1,PALM,SPATA6,RASGRF1,PNMA8A,CPEB3,DDN,ARC,ZEB1,SYNE1,DOCK9,R3HDM1,CHST5,PRMT8,ZMYND8,OSBP2,XRCC4" Drug 3219_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,MRTFA,ASCL1,DNAH17,CACNA1G,BAIAP3,HIP1R,CDH2,NDST3,CNTFR,HDAC9,CTIF,ZNF804A,ST8SIA3,EDNRA,CDKL3,FGFR1,FHL1,PRELID3A,NSG1,FUT9,RND1,GNG3,GPM6A,GRM1,ATXN2L,HLF,SYNPO,HNMT,HPCA,KCNC1,KCND3,MDFI,MYCN,NPTX1,NTRK2,SNTG1,MAPK7,ELOVL2,RIPOR1,CCDC40,RGS12,TCP11L1,SH3BP2,FAIM2,SYT5,RPGRIP1L,TRPM2,VLDLR,FAM13C,PHTF2" Drug 2074_DN Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ADCY6,PPFIA3,APP,CDK10,CFLAR,HIP1R,KIAA1549L,WHRN,SMARCAL1,CSNK1E,PARD6A,ABCC5,E2F5,SIDT2,ZNF589,TRMO,SYT17,INPP5K,GART,SESN1,ZNF276,GNAS,GUCY1B1,INPP5B,MAP4,NPR2,SLC11A2,SETD4,OCRL,PC,PPP2R5C,RAB3A,RGS4,MAP6D1,SH3BP2,ITSN1,EPN2,SCMH1,ELMO2,BTBD7,ZKSCAN3,ARHGEF9,COBL,EXOC7,FBXW11,TCF7L2,TNS2,TRIO,NPDC1,PHTF2" Drug 6443_UP Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ACTN2,APBA2,PPP4R4,ARHGDIG,SLC4A4,RGS11,LDLRAD4,CACNA2D1,CAMK2G,CLGN,COL9A3,CSF1,PDE4DIP,CALY,EDRF1,SRGAP3,SGK2,EFNB3,MTSS1L,ANKMY1,EXTL1,FER,NSG1,FYN,GFER,MYH7,NTRK3,CDK18,NLE1,SLC25A23,LRRN3,PPP5C,PTH1R,SLC6A15,TRIM68,RGS12,CCDC25,TCP11L1,RPS6KA2,ASAP3,SLCO1A2,COA1,SNAP25,IZUMO4,HECW1,PEG10,AJAP1,PLCB1,SYT5,VSNL1,XRCC4" Drug 4609_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,BIN1,CASK,NCOA1,ALDH4A1,ADGRB2,SYNJ2,CFAP410,ARHGEF1,B4GALT6,ABCG2,QKI,HOMER3,CTNND2,PPP6R2,RUSC2,MBNL2,EPB41L1,RRAGB,FER,ANKFY1,DHX35,DIPK1A,INPP5B,MX1,NASP,NDP,NFYA,NUMA1,PAK3,PLCD1,RC3H2,LRP12,WDR25,TMEM231,SH3TC2,GTDC1,TTLL7,CLIP1,ZFP30,COA1,TAB2,NXT2,EXOC7,TCF4,ZNF34,BEX4,CABIN1,NSD2,MAP3K12,EMSY" Drug 452_DN "indomethacin, USP; Down 200; 100uM; PC3; HG-U133A" Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "SERPINA3,ADCY2,CDC42BPA,ANK2,SEMA7A,APBA2,GAS7,ARNTL,ATP2B2,N4BP2L1,HAP1,SCARB1,CHGB,CHRM4,CLCN4,NRG2,RIMS2,HS3ST2,EDNRA,EFNB3,RASL10A,OGA,DISC1,PRRC2B,GPR37,NXPH3,VSIG4,ICA1,LYRM9,NCAM1,NCF2,NELL2,NOS1,NPTX1,PALM,ENPP2,PENK,NLE1,ACSM5,RET,RLBP1,ATXN1,ZNF821,NTNG1,ARHGEF40,FNBP1,SPART,TCF7,SEZ6L,TMPRSS5,VSNL1" Drug 206_UP celecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BRAP,BIN1,APAF1,DGKD,PDXK,ATM,CFLAR,SYNJ1,CACNA1I,CFAP410,SLC25A14,HOMER3,CRMP1,SDC3,EDNRA,YAF2,SPEG,C1orf61,RASL10A,TMEM8B,GRIN1,NR3C1,GRM8,FAM107A,HMX1,KIF2A,ADAM22,MTR,NTRK3,SETD4,ODF2,OPRL1,CAMKV,PLEC,LRRN3,MAPK3,MAPK8,ZFHX4,MAPK12,STUM,FERMT1,IGSF9B,TNIK,TCF7,WDR7,TF,PDIA2,SF1,SLC17A7,EPM2A,FZD3" Drug 4384_UP PHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADGRF5,APC,APOC1,PPP4R4,RHBDL1,CDH10,QKI,SULT4A1,CNTN1,AKAP5,CREM,RIMS2,NOS1AP,DGKG,SPOCK2,ETV1,F5,REEP2,ZNF589,KIAA1109,CHL1,NEU3,GCNT2,GFAP,ATF7,GPER1,GRK4,GRM7,AP4S1,ICA1,MIA2,MOBP,NPY,NOVA2,P2RY1,PFKFB2,PIK3CD,PLCD1,MAPK7,GAL3ST4,TTLL7,RNASEL,EMID1,CPEB3,PKNOX2,SLC11A1,VAMP1,SZT2,UCHL1,LAT2,SLC30A3" Drug 2042_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADORA1,LTBP4,PRX,PDE8B,CA12,CACNA1A,CALB2,CACNA2D2,STOML1,CNTFR,IQCK,CTH,TMCC2,EFNB3,TNK2,SRPK3,ELN,C1orf61,STAG2,GNAO1,GNG3,GRIK1,SPACA9,CACFD1,PRDM5,NXPH3,TJAP1,KCNF1,LAMA2,MBP,MITF,GIT1,SAMD14,DUSP26,CAMKV,PACSIN1,PPARA,CEP41,RGS12,RNASE1,SYNDIG1,RXRA,BCAN,LIMS2,FAM214B,SLC6A11,SPTB,PHLDB1,SYN2,VGF,NUP214" Drug 7522_DN CP-645525-01 [287190-82-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ADORA1,ADORA2A,AK2,MRTFA,APBA2,MARK4,GYG2,FOXN3,FADS2,WHRN,NOS1AP,EXOG,DNM2,DTNA,SNX29,VPS26C,FGFR1,PRKAG2,FOXF2,DPYSL4,FAM49B,GPR153,POLL,GNG4,AFF1,ADAM22,NNAT,PALM,PCDH9,DUSP26,NLE1,PLTP,LRP12,CCDC40,NEK11,EMID1,SYNDIG1,FERMT1,SLC6A8,TTBK2,TBL1X,AHCYL2,TRIO,KCNK12,EMSY,GDPD5,HPS4,NAV2,ITM2C,ACTR3B" Drug 2888_UP Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "TTYH1,SPARCL1,ALCAM,BIN1,CDC42BPA,GYG2,MYRF,CRLF1,TAOK2,NMT2,CRMP1,SIPA1L1,DTNB,EGFR,CALCRL,HSD17B14,ERBB2,SORBS1,FYN,SRCAP,GLI2,ATXN2L,HPSE2,ZNF862,NPTX2,NUMA1,PENK,SERPINE2,SLC25A23,MYH14,RPS6KA2,SYNDIG1,DOCK10,BTBD7,SLN,SNCA,IQSEC2,ARC,EXOC7,KIAA0930,TMEM151B,TMEM121,DAAM2,CABIN1,SEZ6L,TRIO,TRPC1,FAM155A,UCHL1,ITM2C,ADAMTSL3" Drug 1479_DN Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABR,ADD3,AP2A2,APOC1,PPFIA3,CDK10,KIF1A,MPDZ,BCL7A,SYNJ2,BTRC,SPAG9,SCARB1,SMARCAL1,HP1BP3,DTNA,SUGP2,EPB41L2,EZH1,PRKAG2,PDLIM5,GNG4,GPR37,CACFD1,HPS5,HSF2,ITPKB,LIG4,MATK,LRP12,MED1,PTPN13,ATXN1,FNDC3A,EPN2,ELMO2,KDM4B,LHPP,CLASP2,TRIM2,BEX4,TRIO,ZMYND8,UBTF,PLPPR2,VGF,LMF1,NDRG4,WIPF2,MPPE1,PHTF2" Drug 169_DN FK-506; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "GRAMD1B,ADORA3,BCAS1,CDK10,ASCL1,BCL7A,CACNA1I,RAB29,WASF1,MYRF,CFAP410,HIP1R,CBFA2T2,CHRNB2,LY86,CSNK1E,SGK2,DMTN,FAM198B,KIAA1109,BAIAP2,TRMO,NCKAP1,SRCAP,CRCP,GLS,FAM107A,KCNJ5,KIF5C,L1CAM,MBP,AFF1,NPY,OMG,CDK18,EPN1,FA2H,RASGRF1,ARHGEF10L,RLBP1,FOXRED2,KBTBD4,SMARCC2,SON,GLT8D1,ITPRID2,COBL,TMOD1,SSBP2,CADM1,UPF3A" Drug 3706_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "AP2A2,ADGRF5,PPFIA3,CAMK2B,LARGE1,FOXN3,ARHGAP22,KIAA1549L,SH2B1,PDE4DIP,DAPK3,SPOCK3,AK5,ATN1,DTNA,EFNA3,ING4,SPEG,FGF1,BAIAP2,FOXG1,C1orf61,EFCAB2,CINP,PRELID3A,GPM6A,RASSF8,KIF5C,VWA5A,MAPT,ODF2,FSD1,CEP41,PRKAR1B,MAPK8,TCP11L1,ZNF821,ZBTB43,DDN,COLGALT2,SYT11,MLC1,TBCEL,TEX15,TIAM1,TRIO,ZNF24,VPS35L,PHTF2,DPF3,RNF146" Drug 5943_DN rotenone; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BIN1,APBB2,PPFIA3,PPP4R4,SCAPER,CACNA1I,BTRC,CDH10,DNAJB5,SULT4A1,CSF1R,PLCH2,MAML1,CDON,SLC12A6,ATN1,EN2,CEND1,INPP5K,GNAL,GRM7,ICA1,IRF8,INPP5B,PACRG,CD200,BCO1,TAGLN3,NTRK2,PENK,SERPINE2,POU3F2,PTPRH,RAD51D,RGS12,SGK1,SCG5,SLN,SNCA,CLSTN2,PHLDB1,ARC,ADGRL3,TBCEL,WSCD1,TRIM2,DICER1,ZKSCAN5,WIPF1,SPHK2,MAP3K12" Drug 890_DN 5149715; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "LTBP4,BIN1,SYNJ2,CA4,CACNA1D,KYAT1,SCARB1,STOML1,QKI,CRY2,USP6NL,PARD6A,MRNIP,FHL1,EFCAB2,FAM49B,CGREF1,INPP5K,MALT1,HTATSF1,FERMT2,INPP5B,MAP4,MAPT,NEK1,NF1,SETD4,STRN3,PRKAB2,PRPH,SAMD9,RGS10,SFPQ,MAPKBP1,PALLD,ZHX3,ZBTB43,NCDN,SYT1,TACC1,TCF7L2,TRIM2,ZNF34,TIAM1,RBFOX2,CDK20,ZMYND8,VAV1,SF1,MAP3K12,EPM2A" Drug 7204_DN Noscapine [128-62-1]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "APBB2,NCOA1,MTMR9,KIF1A,SYNJ1,PTBP2,SCARB1,SRSF11,STOML1,CREM,LRIG1,MICAL2,DZIP3,ARHGAP32,KIAA0586,DBN1,MED12,DTNA,FEM1B,CELSR3,SUGP2,IRAK4,COQ7,EFEMP1,CAMSAP1,FOXG1,SEMA4D,TXNL4A,GRB10,NR3C1,BTN2A1,MUM1,KHK,RETREG1,MBOAT7,PPP2R5C,MYH14,ROM1,RXRA,MAPK12,SBF1,ZKSCAN3,SMARCC2,KDM4B,CLASP2,NCDN,ELOVL4,WWC1,TCF7L2,PRDM2,GAN" Drug 2272_DN Ornidazole [16773-42-5]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,PLA2G6,C1QTNF3,MRTFA,APBB2,GAS7,APLP1,APOC1,PPP4R4,PLA2G4C,RASL11B,CFLAR,FOXN3,PLEKHB1,FADS2,QKI,CRY2,GREB1,PLXNC1,EML1,COQ7,KIAA1109,PRELID3A,SRCAP,GLYR1,DHX35,HSD17B1,JAK2,KCNJ3,IPO5,VWA5A,ZNF862,MYT1,NUMA1,RETREG1,PRODH,RAB3A,RGS3,TCP11L1,WLS,SH3BP2,ITSN1,LIMCH1,ZCCHC24,SPART,TROVE2,PHLDB1,VAMP1,AP4E1,KCNK12,HPS4" Drug 2529_DN Nadide [53-84-9]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "MTUS1,ANK2,KIF1A,CDK5R1,MTMR3,CACNA1I,CACNA1A,REPS2,CDH8,CDH10,FOXN3,PICK1,AKAP7,IQCK,CSF1,ARHGAP32,DAPK3,CDON,DPH1,EDNRB,MBNL2,EIF4G2,RASGRP2,F5,CAMSAP1,EFCAB2,GAA,ZNF44,TRAF3IP2,ERAP1,SEPT9,KCNMA1,MAP4,MAPT,NF1,LRRN3,PTAFR,RAB3A,RGS3,TCP11L1,SLC11A1,BTBD7,NCDN,SYN2,TAL1,FBXW11,THRA,TMOD1,RBFOX2,FLRT2,SH3GLB2" Drug 5673_DN Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADRA1D,BIN1,APOC1,CA4,PLEKHB1,TAOK2,FAM189A2,AKAP7,CSNK1E,DAPK3,ARMCX2,RCAN1,SIDT2,ANKMY1,FAM198B,KIAA1109,CGREF1,TBR1,GALC,MALT1,GLYR1,ACOT7,HNMT,IPO5,LIG4,LMO2,MMP16,ADAM22,NUMA1,PDE4A,SMIM7,PRODH,PTHLH,ELOVL2,RALGDS,GSTCD,MAPK12,SLC1A7,PEX26,CDK5RAP2,KDM4B,SEMA4A,PDLIM2,TCF7L2,RPGRIP1L,AP4E1,SLC44A1,RPRM,PLPPR2,REEP1,GDPD5" Drug 4773_DN Spectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ARRB2,CDK13,ASPH,STX16,BCL2L2,CFLAR,MTMR2,CA12,SLC25A14,CREM,NCOR1,PDE4DIP,DAPK3,SMG7,NR1D2,GPHN,CDKL3,WAC,POLR1B,FGFR1,PDLIM5,INPP5K,TXNL4A,MSL3,MUM1,IL6ST,KIF2A,MBNL1,NFYA,PIK3R1,STRN3,BSDC1,SLC25A36,ZFP30,ZNF430,ZKSCAN3,POGZ,SS18,KANK1,SYNE2,ANKRD12,TCF7L2,TMPO,KAT6B,RBFOX2,TRIO,TRPC1,LMF1,SH3GLB2,LRP8,FXR1" Drug 2197_UP (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ARID1A,SRPX,APC,GAS7,APP,CDK10,CADM3,CACNA1I,REPS2,CHRNB2,PDE4DIP,TBC1D5,HIPK3,ELN,C3orf18,ANKMY1,BAIAP2,AGAP2,TMEM8B,PCDH17,GLRB,TDRKH,STON1,KIF3A,RASSF8,KCNJ5,KIF5A,L1CAM,OGG1,PDE4A,PFKFB4,PIK3CD,PNMA3,FSD1,MASP1,RELN,SYTL2,BEND5,PREX2,SMTN,RBM34,ATP10B,ATP11A,TCF4,CRTC1,TEX15,TMOD1,TPM1,LMF1,PLSCR4,SENP7" Drug 4825_DN Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,AP1B1,CDK10,MARK4,CFLAR,SCARB1,FAM189A2,PDE4DIP,SDC3,ZNF337,JAKMIP2,G3BP2,DSCAM,SUGP2,EPB41L2,TXNL4A,GNG4,GRB10,MUM1,HSD17B1,MAP4,MAPT,SCAMP5,MITF,ZNF862,NEK1,NUCB1,ODF2,CCSER2,PLXNB1,RC3H2,PMS2,PTK2,RIPOR1,NKAIN1,RAD52,ZCWPW1,SAFB,SBF1,ITSN1,EPN2,SCMH1,SLC20A2,SMARCA4,POGZ,PHLDB1,TACC1,IQCE,RUNDC3B,NSD2,WIPF2" Drug 4398_UP Piromidic acid [19562-30-2]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "SYN3,ASIC1,NDRG2,SEMA6A,BEGAIN,APAF1,CDC14B,PPP4R4,CDK13,CACNA1G,CACNA1D,INA,CDH10,ASIC3,COL9A3,CRMP1,IPCEF1,CTIF,SPOCK3,RCAN1,DCTN2,B3GAT1,TPPP3,FYB1,GRIN1,GRM1,GRM7,KLF12,KCNC1,AFDN,MYCN,NEFM,NEUROD2,SNTG1,PDE1C,FXYD1,MAPK8,KHDRBS2,RGS12,DOCK10,SLC1A2,SLC2A5,KANSL3,SLC11A1,SLCO1A2,KIF21B,NPAS3,SYT11,MLC1,TRO,ADAMTS9" Drug 3745_DN Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,AP2A2,C1QTNF3,SCAPER,CACNA1A,CACNB2,CAST,SYNGR3,ARHGAP33,LARGE1,PLEKHB1,CLCN4,HAPLN1,CRY2,CSNK1E,SLITRK5,CTNND2,SGSM2,OPTN,EIF4G2,MRNIP,SPEG,KAT8,ZNF589,FGF1,EFCAB2,PDLIM5,PRELID3A,SEPT9,RAB30,GNG4,INPP5B,MDM4,PDE3B,MINDY2,FAM120C,CEP97,ZCWPW1,RGS10,MCMBP,ZFP30,DOK5,TROVE2,MAPK8IP3,COBL,RPGRIP1L,TIMP4,TK2,VGF,VIPR2,TIGD6" Drug 5278_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ACTN2,ADCY2,SPARCL1,LTBP4,OGT,CNTNAP1,KSR1,CACNA1I,CDH10,CHGA,TAOK2,PICK1,SDC3,SEC14L5,SPOCK2,CTIF,DMPK,RASGRP2,NCALD,CORO2B,FGFR1,FOXG1,GABRA2,GATM,GFER,AP4S1,ATXN2L,MID1,ZNF862,CLDN11,PLTP,PDZRN4,LRRN3,PTAFR,RGS10,KCTD17,SELL,FAM214B,PKNOX2,MAPKBP1,HECW1,ARHGAP26,DMXL2,DOCK9,R3HDM1,AMACR,UBE3A,EVI5,SLC17A7,KCNAB1,PLSCR4" Drug 2712_UP Sulfameter [651-06-9]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADORA1,PLA2G4C,ARSE,ASCL1,ATP2B3,KIF1A,BMP7,CACNA1G,BTRC,TMEM257,CDO1,CHRM4,RAB26,CREB5,NCOR2,DZIP3,RIMS2,RIPOR2,ATN1,EDNRA,VPS13B,RASGRP2,ERBB4,APC2,FHL1,AGAP2,PRELID3A,GPR153,GABRA2,GPM6B,SCIN,SAMD14,NOVA2,P2RY1,SNTG1,PDGFRA,PRPH,CNNM2,RGS12,KLHDC8A,FRMPD1,RPH3A,PKNOX2,SHANK2,TNIK,IQSEC2,PLCB1,TACR1,ADGRL3,VAV2,JPH3" Drug 461_UP LY294002; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "AMT,OGT,APP,ARNTL,CADM3,RUNX1T1,SRSF11,SLC24A2,LY86,CRMP1,DAPK1,MBNL2,VPS13B,EXTL2,EZH1,TESK2,KIAA1109,NSG1,INPP5K,PCDH17,ZNF638,GNAO1,GRIA4,IRF8,AFF1,MN1,LYRM9,CAMKV,CCSER2,MINDY2,ARID4A,RET,PAQR6,TMEM156,SEMA6D,SBF1,ATXN1,PKNOX2,EFHD1,SNAP25,ZC3H13,CDK19,ATP10B,ZFR2,DMXL2,TCF7L2,WASHC4,SLC13A3,ZNF24,SLC17A7,PLSCR4" Drug 6384_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "DPF1,ALK,BIN1,GAS7,APP,SCAPER,MYRF,VCAN,ARHGEF4,CYBB,SPOCK2,DBT,TMCC2,EFNA3,TENM1,EPHB1,DLC1,FYB1,SRCAP,PCDH17,RUNDC3A,GNG4,GPD2,ADAMTS13,GRM7,HLF,KCNQ3,KIF5C,MDM4,ADAM22,NPR2,NTRK3,TREM2,PDE4A,PIK3CD,PLEC,POU3F4,MAPK8,DIRAS2,PTPRO,FEZF2,RGS7,SLC1A2,SOX10,AJAP1,SYT5,TRIM2,PCDHGA1,ICAM5,TNS1,WIPF1" Drug 3267_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ALK,KCNAB2,MARK4,ATM,CFLAR,BMP7,CRLF1,UBE2L6,LHX2,ZFYVE9,SLC4A7,SDC3,DAPK3,RCAN1,EFNA3,EFNB3,EZH1,FER,KIAA1109,FHL1,OGA,DISC1,FERMT2,GSN,KCNF1,KITLG,NF1,NPTX1,PDE3B,PPP5C,RAB3A,CEP97,ATG16L1,RGS12,ROM1,NEK11,EMID1,FOXRED2,RASA3,SGK1,BTBD7,FNBP1,EMC1,FCHO1,CEP68,VAMP1,CHST8,PARD3,VGF,EPM2A" Drug 1464_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NME5,APBA2,BCAS1,APP,ALDH4A1,SLC2A11,ATP6V0A1,CDK5R1,ST3GAL5,SCAPER,BTRC,CFAP410,CAMK2B,CBFA2T2,ASIC3,BAG4,GREB1,DCAF4,DMPK,EDNRA,ABI2,CAMSAP1,IQCG,CINP,TDRKH,MAP4K5,IGSF1,KCNH2,MBD1,KITLG,CD200,OPCML,PRODH,GON4L,PTPRE,CHD9,SLC9A5,SLC15A2,KDM4B,ZCCHC24,MAPK8IP3,ELOVL4,ARC,MCF2L,TK2,TMOD1,BEX4,KCTD2,CDK20,WIPF1,SLC30A3" Drug 3396_DN Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ARID1A,NME5,LTBP4,BIN1,APLP1,CDK13,DNAH17,MARK4,ASPH,SCAPER,CFAP410,SLC16A4,CLGN,CACNA2D2,FADS2,ARHGEF6,WHRN,ATRNL1,PDE4DIP,RIMS3,ATN1,CELSR3,PLXNC1,DMTN,LRRC23,ZNF589,IQCG,TMEM8B,RUNDC3A,ELOVL5,ZNF862,P2RY1,PCDH9,CDK18,PDE3B,PLCD1,PTN,ZFHX4,DOCK10,PEX26,SLC9A5,DOK5,THSD1,INKA2,SMG6,DOCK9,TMOD1,FAM155A,REEP1,DNALI1" Drug 7261_UP Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "APC,ASPH,ZBTB10,ARHGEF7,SCAPER,CFAP410,CBFA2T2,SRSF11,SOCS6,PLEKHB1,NIPBL,CSF1R,PDE4DIP,DZIP3,MFAP3L,RABGAP1L,E2F5,EDIL3,IRAK4,EML1,COQ7,CDKL3,KIAA1109,TRMO,PDLIM5,GLI2,GLRB,GUCY1B1,DIPK1A,KCND3,KIF5C,KPNA5,NNAT,SETD4,PFKFB2,PMS2,MAPK3,NCBP3,TRAPPC13,PPP1R9A,DOCK10,AMBRA1,ELMO2,KDM4B,SS18,PHLDB1,SYT1,DOCK9,HPS4,NUP214,RNF170" Drug 4958_DN Theobromine [83-67-0]; Down 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BRAP,MRTFA,AMT,APP,NUMB,CFLAR,C5,CCNT1,CBFA2T2,ZFYVE9,QKI,AKAP7,NECTIN3,ENTPD4,FEZ1,DZIP3,ARMCX2,E2F5,EFNA3,RGS17,EPB41L1,ANKMY1,PRELID3A,SRCAP,MALT1,GRB10,CACFD1,MAPT,ZNF862,NEK1,NFYA,NUMA1,PCDH9,SLC25A23,PRODH,TMEM104,ATG16L1,ZDHHC14,ZNF331,SAFB,ZNF821,PEX26,EPN2,EMC1,SEMA4A,VLDLR,REEP1,WNK1,EVI5,HPS4,ST7" Drug 2925_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADORA1,APBB2,CDC14B,NCOA1,RASL11B,LDLRAD4,CA8,CACNG1,REPS2,CHRNA4,CLCN4,SULT4A1,RAB26,HOMER3,ABCG1,DAPK3,DBT,SPOCK3,SHANK1,ST8SIA3,SORBS3,STX2,ETV1,C1orf61,GPR153,B3GAT1,GABRB1,GAD2,LILRA2,GRIK5,GSN,KCND3,KCNH2,GIT1,NNAT,CNOT4,PFKFB2,PFKFB4,RIPOR1,ZMAT4,RGS10,RIT2,RPH3A,SLC11A1,ARHGAP26,FCHO1,EXOC7,TRPC1,VAV2,PARP11,TIGD6" Drug 3107_UP Adrenosterone [382-45-6]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ACTN2,GRAMD1B,ALK,BIN1,BMP7,MYRF,CAMK2B,CLDN10,CACNA2D2,ASIC3,CHN2,VAX2,SULT4A1,CLOCK,SPOCK3,SGSM2,CDON,DYRK1A,SIDT2,EFNA3,ZNF549,F5,HPCAL4,GPR153,GAP43,SRCAP,RUNDC3A,GNAL,GPD2,GPR22,GRIA4,KLF12,SCRG1,ITPKA,SCAMP5,LYRM9,NF1,PPP5C,PRPH,ROM1,MAP6D1,SEMA6D,SBF1,GALNT10,ST6GAL1,CNKSR2,SORCS3,TMCC1,PLCB1,CDK20,PLPPR2" Drug 2249_UP Ampyrone [83-07-8]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "BIN1,CDC42BPA,APAF1,KCNAB2,MARK4,ADGRB3,BTK,SGCE,BAIAP3,HOMER3,CNTN1,SPOCK3,DRD1,ST8SIA3,SNX29,EFNB3,KCNMB2,EFS,FHL1,AGAP2,PRELID3A,GAD1,RND1,PRDM5,GRM8,IL6ST,ITGAM,KCNMA1,MAP4,BCO1,MYT1,NF1,OMG,LRP12,RETREG2,MAPK7,PTAFR,PTPRO,RAD52,ZMAT4,TRIM68,SYNDIG1,SH3BP2,ST6GAL1,SLC11A1,MYH15,TSNAXIP1,HECW1,KIAA1107,EVI5,SLC17A7" Drug 1753_UP Noscapine [128-62-1]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,ACTN1,NDRG2,ADCY2,ADCY6,ADORA1,CDK10,CADM3,NRP2,CD86,IQCK,ARMC8,CREM,FEZ2,OSBPL3,HP1BP3,DMTF1,DPH1,FAM13A,ING4,DMTN,SEC23B,TRMO,ATP2C1,RUNDC3A,GNAS,ACOT7,TJAP1,VWA5A,AFF1,NEFH,NELL2,NPY,OGDH,OLR1,PDE1C,PDE4B,PMS2,PACSIN1,PTK2,MYH14,LGR4,ARHGEF40,CCDC88A,TMCC1,DOP1A,THSD1,VIPR2,LAT2,ZNF142,AAAS" Drug 3018_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "C3orf14,ADORA3,MRTFA,ANK2,APAF1,APBB2,NCOA1,ATP2A2,AZGP1,SOCS6,ZFYVE9,FAM149A,CSNK1E,TM9SF4,KIAA0753,SMG7,HIPK3,FAM13A,MBNL2,AASS,ZNF589,C1orf61,FLT1,CAMKK2,GABRA2,GABRA4,INPP5K,ALDH1L1,KCND3,KIF2A,MAP4,GIT1,NNAT,CNOT4,PMS2,RAD52,RALGDS,ZDHHC14,TRIM68,RGS3,ZFP30,SH3BP2,SNAP25,WDTC1,SPTAN1,RAP1GAP2,CDK20,TRO,UBTF,XRCC4,PHTF2" Drug 3026_DN Ioversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,ARID1A,BCAR3,PKP4,ASPH,NCOA1,RIPK1,KIF1A,AZGP1,CACNA1A,CAMK2G,HIP1R,SCARB1,CLGN,CLCN4,NMT2,SLC4A7,SH2B1,TM9SF4,DTNA,TOM1,EEF1A2,HIPK3,CELSR3,ABI2,ECSIT,PDLIM5,KHDRBS3,GABRA4,ZMYND11,LILRA2,NCKAP1L,ATXN2L,PPARA,WDR25,TRIM68,RGS10,ZC3H14,ZNF671,CLIP1,RASA3,SPTAN1,NCDN,KIAA1107,TCF4,TCF7L2,SZT2,RBFOX2,SSBP2,TRIM9,EMSY" Drug 7557_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RALGAPA1,NDRG3,ADCY6,APAF1,APBB2,APC,APOC1,ARNTL,MARK4,ALDH7A1,BAIAP3,CBS,CNOT8,KIAA1549L,NIPBL,ARHGEF6,IQCK,ABI3BP,ENTPD4,CNTNAP2,PPP6R2,GIT2,SMG7,ABI1,EDIL3,EDNRA,APH1A,ST3GAL6,TRMO,PDLIM5,DLL3,DENND2A,MSL3,DIDO1,IFI16,SCIN,ITGA7,PPP3CC,PRKAB2,RAB3IL1,IL17RB,WDR47,IFT122,LIMCH1,KDM4B,ANKRD12,TCF4,AHCYL2,METTL3,TRPC1,PCBP4" Drug 4992_DN Progesterone [57-83-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,APP,ASPH,HIP1R,KRIT1,LHX2,QKI,SLC4A7,AKAP12,DZIP3,RIMS3,INTS1,HP1BP3,LYPD1,PARD6A,RABGAP1L,MED12,DTNA,ACSL4,GPR153,GART,MSL3,AGBL5,HSD17B1,RBPJ,INPP5B,KCNJ3,NUMA1,LRP12,FSD1,PRPH,RIPOR1,RAB3A,RALGDS,RGS10,RNASEL,FBXW7,FOXRED2,FBXO11,FNDC3A,URGCP,LIMCH1,SPART,MAPK8IP3,CEP68,COBL,MCF2L,TRIM2,RPGRIP1L,TMPO,NUP214" Drug 4791_DN Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "SLC12A5,CDC42BPA,BCAS1,ARNTL,CA12,ARHGAP33,VAX2,AKAP7,SH2B1,SDC3,DBT,PARD6A,DTNA,MAMLD1,CNNM1,ENO2,CAMSAP1,FHL1,ERAP1,DIDO1,KCNJ3,MAP4,MAPT,LYRM9,NFYA,RETREG1,PLEC,GON4L,WDR25,GTDC1,RNF220,SBF1,EPN2,SMTN,SOX2,ZCCHC24,EMC1,IQSEC2,TROVE2,NCDN,ATP11A,ROBO3,KIAA0930,TMEM121,TK2,ZNF384,ZKSCAN5,VAV1,VGF,ZBTB14,ST7" Drug 4978_DN Lovastatin [75330-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABHD6,ACTN2,PLA2G6,APP,BCL7A,CFAP410,CA12,CACNA1D,CAMK2G,ARHGEF4,IRAK4,MRNIP,BAIAP2,HBS1L,INPP5K,SRCAP,RAB30,POLL,GRB10,CACFD1,BTN2A1,ITPKB,NEK1,NPR2,NPTX1,NUMA1,SETD4,LRP12,PPP2R5C,PRODH,PTHLH,RIPOR1,RALGDS,RGS3,ARHGEF10L,PEX26,EPN2,SMTN,LIMCH1,SEMA4A,ROBO3,TBL1X,AP4E1,ZNF34,TK2,TMOD1,CABIN1,ZKSCAN5,VAV2,ZNF45,MPPE1" Drug 2453_UP Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ACTN2,NDRG2,PPFIA3,ALDH4A1,RIPK1,BACH1,CFLAR,CACNA2D1,CHN2,HOMER3,COL9A3,CLOCK,PDE4DIP,EDRF1,DTNB,EIF1,DLC1,OLFM1,FGFR1,ANKFY1,KHDRBS3,OGA,TRAF3IP2,SIGLEC8,GNG3,GNG4,ATF7,GUCY1A2,KIF5A,KPNA5,MAP4,AFF1,PDE4D,PFKFB4,CAMKV,CCSER2,PLCD1,PLP1,BCAS3,WDR25,GAL3ST4,SLC1A3,ZC3H13,LHPP,MAPK8IP3,AP4E1,GPR161,TLR4,TPM1,KCNAB1,GJC2" Drug 4150_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,KIDINS220,BIN1,FAM131A,ALDH7A1,NRP2,CACNA1D,NEURL1,PLAA,CLCN4,WHRN,RCHY1,SH2B1,CRMP1,CRY2,NOS1AP,SPOCK2,DYRK1A,HIPK3,ELN,ERCC2,DLC1,OLFM1,FGFR1,FHL1,SEPT9,LYVE1,TJAP1,ITIH2,MX1,MYT1,NEUROD1,NOS1,CNOT4,MINDY2,PPP2R2B,ZNF821,SH3BP2,LIMS2,FAM214B,SLC6A8,ZCCHC24,ZHX3,ZC3H13,SYT5,PSD3,PCDHA5,HEY2,VAV2,PRDM2,PLSCR4" Drug 2575_DN Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "MRTFA,BIN1,APC,CDC14B,ADAM15,BCL7A,MTMR3,C5,LDLRAD4,CAST,REPS2,FAM149A,ENTPD4,RIMS3,CDON,SEZ6L2,RASGRP2,MTSS1L,DLC1,ST3GAL6,PRKAG2,ERAP1,SRCAP,ATXN2L,ELOVL5,KHK,MEF2C,NOS1,OGG1,PDE4D,CCSER2,MAPK7,PLPPR1,PTPRO,RIPOR1,RAD52,FAM184A,RGS10,CNKSR2,EPN2,SIRT2,CEP68,IQCE,FBXW11,TCF7L2,TNS2,CRTC1,SLC44A1,TNNT1,LMF1,STMN4" Drug 1320_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ABAT,ABHD6,AP2A2,DOC2A,STX16,SYNJ1,SCAPER,NFS1,CLGN,SLC4A7,BAG4,CPS1,OSBPL3,ZFYVE16,DBT,SPATA2,GSDME,DLG4,HIPK3,PTK2B,SEPT9,GLYR1,NCKAP1L,MAP4,N6AMT1,PIK3CD,RETREG1,MINDY2,MAPK3,GON4L,C1orf109,TMEM231,RASA3,FUZ,MYH15,CLUAP1,ZBTB43,PBLD,MAPK8IP3,EXOC7,CAMSAP2,TCF7,SLC44A1,KCTD2,KAT6B,SMUG1,ZMYND8,TFIP11,WNK1,KCNAB1,MARCH8" Drug 4977_UP SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NME5,AK2,LTBP4,TRMT9B,APBA2,APC,ATM,SLC2A11,SYNJ2,CACNA1I,BAIAP3,CACNA2D2,CHM,HOMER3,WHRN,CSF1R,ARHGEF10,RIMS2,RIMS3,DAPK3,SMG7,SIDT2,DMTN,ZNF589,FOXG1,AGAP2,USP19,MAP4,MOBP,NELL2,NNAT,CNOT4,NPR2,RETREG1,NLE1,MED1,PTH1R,C1orf54,ZNF493,DOCK10,COA1,KIF21B,ARHGAP26,AJAP1,VAMP1,SZT2,CRTC1,CABIN1,ZMYND8,HIRA,ZBTB14" Drug 4216_UP Minoxidil [38304-91-5]; Up 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "RGS9,NRP2,KSR1,BMP7,BAIAP3,MTMR7,NEURL1,ARHGEF2,DLGAP1,COL9A3,TCEAL2,ATRNL1,RIPOR2,SPOCK2,BRINP1,DCC,SRGAP3,SGSM2,TRAPPC9,PLXNC1,AASS,ATP8A1,ST3GAL6,PDLIM5,ZNF44,SIGLEC8,GLI2,GNAL,GRM8,ATXN2L,HNMT,HTR5A,ICA1,KCND3,AFDN,ADAM22,DDX25,PMP2,PTAFR,PTCH1,SCN2B,FRMPD1,SLCO1A2,SNCA,IZUMO4,INKA2,MAPK8IP3,TACR1,TNS1,WIPF1,KCNK12" Drug 6395_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ADCY6,GAS7,APOC1,MYOM1,ADGRB3,CFLAR,CDK5R2,HAP1,CLCN4,ARHGEF6,CPS1,HAPLN1,PPP1R16B,CTIF,HS3ST2,VPS13B,ST3GAL6,FGFR1,FOXG1,PDLIM5,RASL10A,CHL1,SEPT9,LILRB4,GPR17,GPR22,HLF,ITIH2,MAOB,ADAM22,SAMD14,MYO7A,PENK,SEPT4,SAMD9,PTN,MARCH1,FEZF2,KHDRBS2,SYNDIG1,BCAN,UNC5B,ATP10B,ABCC8,SYT5,CUX2,SLC35G2,FLRT1,MKRN3,PRDM10,AP3B2" Drug 6250_UP Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "TRMT9B,AMPD3,SLC4A4,CACNA1A,CAMK2G,ZFYVE9,QKI,ATRNL1,CTH,GIT2,HP1BP3,EFNA3,ZNF589,BAIAP2,FHL1,ATP2C1,FYB1,GNAS,TDRKH,GRIN2C,MAP4,AFF1,ADAM22,NDUFA5,OPRL1,PDE3B,PLCD1,POLG,MAPK10,ZCWPW1,KCTD17,MYH14,GSTCD,SH3BP2,FBXO11,SYBU,ANKRD6,PPP4R3A,SLC15A2,KIF21B,ZSWIM8,ZNF423,SPTAN1,EXOC7,AP4E1,TK2,RUNDC3B,ZKSCAN5,KCNK12,ADAMTS9,TIGD6" Drug 502_DN sodium 4-phenylbutyrate; Down 200; 200uM; SKMEL5; HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,NDRG2,PKP4,PPFIA3,ATP1A3,BMP7,CD86,B4GALT6,JAM2,TMEM59L,COL4A5,CDC42BPB,ARHGEF10,DGKG,DRP2,SIDT2,ELAVL4,BSCL2,ZNF589,FGFR1,FGFR3,TRMO,B3GAT1,GAB1,LYVE1,HPGDS,CACFD1,GRM1,FAM107A,GUCY1A1,MAN1B1,HNMT,KIFC3,FXYD7,NF1,PRKAR1B,PYGM,RGR,RGS3,PPP1R9A,SMARCC2,ZSWIM8,IQCE,SIRT1,HEY2,TPM1,SSBP2,UGT8,NSD2,KLC2,SLC17A7" Drug 6360_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG3,GRAMD1B,KIDINS220,AP1B1,PPFIA3,SLC4A4,FUBP1,C5,QKI,GIT2,CNIH3,SGSM2,DLG3,DNM2,EPB41L1,FCGRT,EFCAB2,ATP6V1H,MPP6,GPER1,GUCY1A1,MAP4K5,IL11RA,MAP4,MAPT,MATN3,GIT1,OPCML,PC,PRPH,MYH14,FBXW7,MAPK12,URGCP,LIMS2,ZKSCAN3,SMARCA4,TNIK,BEX1,SPTAN1,STX1A,SYT11,SMG6,HIRA,NDRG4,SH3GLB2,EMSY,NT5M,SCG2,PCBP4,WIPF2" Drug 4021_DN Nadolol [42200-33-9]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,GRAMD1B,ADGRF5,MRTFA,APP,PDE8B,DNAH17,ASTN1,ATP2B3,KIF1A,CACNA2D2,FOXN3,ARHGAP22,RAB26,WHRN,COL9A3,CSF1,ARHGEF10,MICAL2,VCAN,PARD6A,AASS,DMTN,AFF2,ZNF44,AHDC1,USP19,MSL3,POLL,GPD2,GPR19,GRM8,TJAP1,ITPKA,VWA5A,MX1,OPCML,CLDN11,EPN1,FSD1,PRKAR1B,PTN,RAB3IL1,KHDRBS2,FRMPD1,FUZ,ARHGAP26,MAPK8IP3,ARC,ASTN2,ADGRL3" Drug 2555_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG3,ADRA1D,GAS7,NCOA1,SYNJ2,SCAPER,C5,LDLRAD4,CACNA1A,RCBTB2,STOML1,SIPA1L1,VCAN,ARHGAP32,CDON,EEF1A2,PLXNC1,MRNIP,LRRC23,FGFR1,EFCAB2,PDLIM5,ZNF44,ERAP1,COPS8,GLS,MSL3,NCKAP1L,ATXN2L,MAP4,MEF2C,NRGN,PDE4D,NLE1,RNASEL,SBF1,MRAS,CNKSR2,RAB3GAP1,ELMO2,ARHGAP26,SPTAN1,PJA1,EXOC7,TCF7L2,TNNT1,TNS1,CDK20,LMF1,GDPD5,PCBP4" Drug 1629_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "NDRG2,PLA2G6,CDC42BPA,GAS7,APP,MARK4,CDK5R1,BTRC,CAMK2G,VAX2,HOMER3,SLC4A7,RIMS2,RABGAP1L,RCAN1,DTNA,EXTL2,KAT8,FLNC,TRMO,ZMYND11,GNG4,GRIK5,HNMT,LMO2,MID1,MKLN1,NTRK2,PCDH9,PDPK1,PLXNB1,MED1,MAPK8,GSTCD,TCP11L1,ZNF821,AMBRA1,FBXO11,PREX2,PEX26,SNCA,INKA2,PCDHGA10,CRTC1,HEY2,TMOD1,BEX4,KAT6B,VGF,SYNC,MAP3K12" Drug 7524_UP Suramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "CDC42BPA,PPFIA3,SEMA4G,CAPRIN2,ATP1A2,ATP1A3,RGS11,CACNA1I,BAIAP3,CFAP410,CAMK2G,ARHGAP33,TPP1,KIAA0586,GIT2,SPOCK3,DYNC1I1,DMTN,LRRC23,ERCC2,ZNF589,FLNC,TPK1,SEPT9,PCLO,GRB10,ADAMTS13,DHX35,HSD17B1,ADAM11,MMP17,NF1,PFKFB2,RAB3IL1,SCN8A,ASAP3,PEX26,BTBD7,ZC3H13,ARHGAP26,MAPK8IP3,SYT11,SZT2,PCDHGA10,SYNE1,TMOD1,TNS1,ZKSCAN5,CLIP2,SPHK2,MVB12B" Drug 2709_DN Sulfanilamide [63-74-1]; Down 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.80E-04 1.00E+00 1.71E-03 1.95E-02 51 198 "ASIC1,ADRA1D,PPP4R4,NUMB,ATP2A2,ATP6V0A1,CDK5R1,FUBP1,CLGN,AKAP7,ARMC8,CREM,ENTPD4,PDE4DIP,PPP1R16B,CTNND1,RHOBTB1,CNNM1,EFNB3,ZNF589,KHDRBS3,ERAP1,WASF3,ZNF276,GNG4,LILRA2,SMAD1,NFYA,CNOT4,SLC11A2,SERPINE2,ST8SIA5,C11orf49,PILRA,POU6F1,PTPRO,MRPS18A,SH3BP2,SLC2A5,SPTB,RBM26,JMJD6,EXOC7,KIAA1107,TCF7L2,CRTC1,TK2,RBFOX2,TRPS1,SH3GLB2,MAP3K12" Drug DB00349 Clobazam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB00842 Oxazepam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000141200 isobutyllithium Stitch 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "SOCS5,BOC,POLL,PMP2,SOX10,SYNE1,GAN" Drug CID000198695 NS-105 Stitch 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug DB01068 Clonazepam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB00690 Flurazepam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB01558 Bromazepam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000166928 AC1L4YZD Stitch 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "LHX2,CTH,IGSF6,MAT2A,RDX,RYR1,CLSTN2" Drug DB00683 Midazolam Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000445835 Aglucovancomycin B Stitch 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "BBS2,CCK,INA,CBX1,STMN1,PMP2,LRRC4" Drug DB00475 Chlordiazepoxide Drug Bank 1.82E-04 1.00E+00 1.73E-03 1.97E-02 7 10 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000031782 AC1L1MBN Stitch 1.84E-04 1.00E+00 1.75E-03 1.99E-02 26 81 "API5,NIPA1,CA8,CHGA,TAOK2,CTH,SLC12A6,ATL1,BSCL2,GHR,RND1,GRK4,NR3C1,KIF5A,L1CAM,PENK,PLP1,PMP22,PPP2R2B,ATXN7,SPART,TAC1,TCF4,TCF7L2,UGT8,GJC2" Drug ctd:D013793 Thallium CTD 1.85E-04 1.00E+00 1.76E-03 2.00E-02 11 22 "SLC12A5,GRM8,KCNH2,KCNJ3,KCNJ4,KCNMA1,KCNN1,KCNN2,KCNN3,KCNQ2,KCNQ3" Drug CID000127296 PP-IP(5 Stitch 1.85E-04 1.00E+00 1.76E-03 2.00E-02 11 22 "IP6K1,IP6K2,IP6K3,HSP90AA1,ITPKA,ITPKB,MAPK3,RAB3A,RAB3IL1,NUDT11,NUDT10" Drug CID005282252 NS 102 Stitch 1.85E-04 1.00E+00 1.76E-03 2.00E-02 11 22 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3" Drug CID000119194 imidazenil Stitch 1.85E-04 1.00E+00 1.76E-03 2.00E-02 11 22 "ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GRIA1,RELN" Drug CID000162797 HWA 153 Stitch 1.85E-04 1.00E+00 1.76E-03 2.00E-02 11 22 "PDE8B,ALDH7A1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000560437 MeIle Stitch 1.87E-04 1.00E+00 1.77E-03 2.02E-02 22 64 "ATP2B1,SLC24A2,GAL3ST1,SV2A,GAP43,GRIA1,GRIK1,KCNC1,KCNC2,KCNJ5,NAP1L2,NPY,PEX5,SCP2,SLC8A2,SLC8A3,ERC1,SST,TRH,PORCN,SLC17A7,SLC17A6" Drug CID000016230 amiloride Stitch 1.90E-04 1.00E+00 1.80E-03 2.05E-02 74 315 "ASIC2,ASIC1,ADD1,SLC24A4,ATP1A1,ATP1A3,SLC4A4,ATP1B3,CACNA1I,CA4,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,CACNA2D2,ASIC3,CHRM1,CHRNA4,SLC24A2,CLTC,SULT4A1,SLC4A7,SLC32A1,GPSM1,TSPAN5,EDNRA,CACNG7,EGFR,EIF5,ERBB2,ERBB4,CACNG3,CACNG2,SLC9B2,ACTL6B,GLRB,LOXL3,NR3C1,KLF12,KCNK3,KCNN1,LIG4,HCN1,PDPK1,PKD1,SLC25A23,MED1,PRKCB,PRKCG,RYR1,RYR3,SCN4B,ASIC4,SLC8A2,SLC9A5,SLC12A2,SLC14A1,SCN3B,STX1A,TAC1,TAC3,TPCN2,SLC19A3,ACTR6,TRPC1,TTPA,SLC47A2,WNK1,SLC17A7,WNK3,SLC17A6" Drug ctd:D014810 Vitamin E CTD 1.90E-04 1.00E+00 1.80E-03 2.05E-02 302 1594 "SERPINA3,ACHE,NDRG2,ADCY2,ADCY6,ADD1,ADD3,AP2A2,OSBPL1A,ALAD,LTBP4,BIN1,CDC42BPA,ANK3,APBB2,APP,AQP4,CDC14B,CDK10,ARHGDIA,CDK13,CAPRIN2,SLC4A4,MTMR9,ADGRB1,BARD1,BCHE,CFLAR,SYNJ2,SCAPER,THSD7A,CAMK2B,CAMK2G,RUNX1T1,LDB2,CD86,CDC25B,CDC27,ZBED1,LRRFIP1,SRSF11,CLCN3,CLU,TPP1,STOML1,CLTB,NIPBL,RAB26,IQCK,FAM149A,SLC4A7,RCHY1,IFFO1,NCOR1,CSNK1E,CSNK1G3,CST3,SDC3,PPP6R2,TCAF1,DCAF8,ZNF337,DAPK3,CEP170,RHOBTB1,SACS,SGSM2,SEC16A,USP3,DMTF1,DNM1L,FIS1,E2F6,EDNRA,PHC2,EEF1A2,EEF1D,EGFR,AASS,EIF4G1,EIF5,PLEKHA1,BSCL2,USPL1,PLEKHO1,ENO2,EPB41L2,RASGRP2,ERBB2,DENND4A,SPEG,ECSIT,EZH1,F3,TUBA1B,TUBB3,FECH,FOXF2,VTI1B,SYNCRIP,FOXM1,EVL,NOP56,FOLH1,STAG2,ZNF44,RAPGEF6,ZNF274,INPP5K,GFAP,DHRS4,TCERG1,RNPS1,GLI2,OS9,POLL,GNAS,GNG4,ADAP1,GRIA2,GSN,GSTM5,FAM107A,MAP4K5,HBA1,MAN1B1,HMGB1,SYNPO,HNMT,HSP90AA1,SMAP1,ICA1,IDH3B,TUBB2B,ITPKB,KCNH2,KCNJ5,KIF5C,KLC1,KTN1,LAMP2,PAXBP1,MAP4,MAPT,MBD1,MBNL1,CHST6,TM6SF1,MOG,BCO1,MSRA,MT3,THYN1,MX1,MYO6,HNRNPM,FXYD6,NEK1,NFE2L2,NOVA1,SLC11A2,NUMA1,OPA1,PCDHGC3,PDGFRA,PDPK1,PFKP,GDAP1L1,NOMO2,PIK3CD,PIK3R1,PKD1,RETREG1,PKM,SMOX,MBOAT7,TNPO2,MED1,PTPA,PKN2,MAPK3,MAPK8,PIGG,TMEM260,PTPRD,PTPRO,PEX5,TUG1,CEP97,USP47,FAT4,ZCWPW1,RBBP6,KCTD17,SLC25A36,ALG9,RPL38,RPS6KA2,MAP6D1,SYNDIG1,WLS,CLIP1,ZNF331,S100B,SATB1,ATXN7,GALNT10,PPP1R9A,FERMT1,KIF16B,ASAP3,AMBRA1,SEC31A,EPN2,SMTN,RUFY2,SLC6A8,ZNF430,SEPHS1,SHANK2,SLC12A2,SCMH1,RCOR3,TTC17,LIMCH1,SNAP25,USP33,SON,TNIK,ZCCHC24,FNBP1,UHRF1BP1L,SPTAN1,SPTB,KIF1B,LMO3,SRPK2,TROVE2,COLGALT2,ST5,NACAD,NCDN,MPRIP,APOM,SEPT8,NSFL1C,SUPT5H,PRRC2C,MMS19,ANKRD12,PJA1,TAF6,FAM208A,PDLIM2,AGTPBP1,TBL1X,SMG6,KLHL4,ATMIN,EHBP1,WSCD1,KIAA0930,TCF7L2,ZEB1,TNS2,DICER1,SIRT1,ITGB3BP,NACC2,TJP1,CBX5,DAAM2,KCTD2,R3HDM1,PARD3,TNS1,RBFOX2,TPM2,WBP2,RUNDC3B,TRO,TSC2,TTC3,TTPA,RPRM,UBE3A,UCHL1,UGT8,VGF,SF1,REEP1,ZNF195,FTSJ1,ZFAND5,UPF3A,EMSY,PRDM2,EVI5,NAV3,ITM2C,C12orf4,FXR1" Drug CID004393961 "1,1'-Carbonyl-di-(1,2,4-triazole)" Stitch 1.91E-04 1.00E+00 1.81E-03 2.06E-02 16 40 "NCOA1,COG1,SUMF2,NCKAP1,GFAP,GGT7,GGT5,GPT2,ENPP2,PSMA6,SHMT2,ST6GAL1,TF,TSC1,TSC2,PMEPA1" Drug CID004369084 PNU-107859 Stitch 1.92E-04 1.00E+00 1.82E-03 2.07E-02 46 174 "ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,PDE8B,PTCH2,ATM,STX16,LRBA,CHGA,CHGB,RAB3C,STOML1,CNTFR,CRHBP,WDR20,GAA,PCSK1N,GNAS,MCHR1,NR3C1,SCG3,FXYD6,NNAT,NPY,NPPA,PCSK1,PCSK5,PCSK2,PDYN,PENK,PRKACB,NDUFS7,RAB3A,PBRM1,RTN1,SCG5,SNAP25,SST,SSTR1,SSTR2,ADHFE1,SYT4,TRH,SCG2" Drug ctd:C060229 "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione" CTD 1.95E-04 1.00E+00 1.85E-03 2.10E-02 21 60 "AGT,CACNA1E,CAMK2A,CCK,CHRM1,EDN1,EDN3,EDNRB,EGFR,PPP1R1B,GFAP,GNAS,NEFM,NOS1,NPPA,OXTR,PLCD1,MAPK3,MAPK8,PLCB1,TAC1" Drug CID000005578 trimethoprim Stitch 1.96E-04 1.00E+00 1.85E-03 2.11E-02 30 99 "ASIC1,TAOK1,MRTFA,ATP2A2,ASIC3,TAOK2,SUMF2,CSF2RA,CYBB,STX2,FOXG1,AFF2,INSM2,GRIA1,HNRNPK,MSRA,NOVA2,PAH,QDPR,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,BEX1,ST5,NPL,FXR1,ST8SIA2" Drug CID000001912 8-bromo-cAMP Stitch 1.99E-04 1.00E+00 1.88E-03 2.14E-02 64 264 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,ARRB1,SLC4A4,ALDH7A1,CACNA1D,CACNA2D1,CACNB2,CALM1,CCK,CCKBR,ARHGEF1,LRBA,CHRM1,AKAP5,CPS1,CREM,NCOR1,CALY,DMPK,DRD1,EDN1,CACNG2,FGF1,GALC,ARPP21,GDF9,GRK4,RAPGEF4,NR3C1,PTPN5,GUCY1A2,GUCY1B1,HRH3,TNFAIP8L3,HSD17B1,IGF1,IGFBP1,KCND2,NF1,NPR2,KCNK10,PDCD2,PDE3B,PENK,PRKACB,PKIA,PRKCB,PRKCG,MAPK3,MAPK7,PTH1R,RTN1,RXRG,SLC1A3,SST,TRH,VGF,VIPR2,AP3B2" Drug 4439_UP prochlorperazine dimaleate salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.99E-04 1.00E+00 1.88E-03 2.14E-02 48 184 "NDRG2,ADRA1D,PDE8B,ATM,CBS,CDO1,SULT4A1,IFFO1,CTH,DCT,TRAPPC9,SNX29,CELSR3,ETV1,REEP2,ATP8A1,ST3GAL6,CAMSAP1,FOXG1,GAP43,RND1,GLI2,FERMT2,GRB10,GRM1,IL6ST,KCNF1,KCNH2,KCNK1,MAP2,MT1M,POU6F1,PPARA,SNRK,PTAFR,PTPRN2,MARCH1,C1orf54,GAL3ST4,RGS4,RNASEL,FAM214B,ARHGAP26,PLCB1,SYT1,TCF4,TRPC1,VSNL1" Drug 5228_UP 15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.99E-04 1.00E+00 1.88E-03 2.14E-02 48 184 "NME5,BIN1,MARK4,BACH1,SYNJ2,GYG2,BTRC,CACNA1A,HAP1,SLC16A4,ARHGEF2,CLGN,SOCS6,PLAA,FADS2,CREM,CRY2,CTH,HIPK3,MBNL2,FECH,FGFR1,BAIAP2,IP6K2,GLYR1,POLL,IL6R,ADAM22,NAP1L2,PIK3CD,PLCD1,NECAB2,PPP5C,BSDC1,TTLL7,ROBO1,ROM1,ZNF821,ZNF365,KIF21B,STX1A,WSCD1,TRIM2,ARHGEF12,UCHL1,VLDLR,ZFAND5,SCG2" Drug 2729_UP Securinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.02E-04 1.00E+00 1.91E-03 2.17E-02 49 189 "PLA2G6,BIN1,CDC42BPA,DNAH17,RHBDL1,CHN1,JAM2,ZFYVE9,CREM,AATK,CTNND1,SNPH,DMPK,MAMLD1,EDN3,EBI3,EGFR,EIF5,EN2,RASGRP2,REEP2,TBC1D16,HPCAL4,DCTN2,SRCAP,GPM6B,ADAMTS8,HTR2A,IL6ST,KCNQ3,MAPT,MN1,NF1,CLDN11,PDE3B,PDE4D,PLP1,NECAB2,MBOAT7,PKN2,PBRM1,AJAP1,ADGRL3,PCDHGA10,AHCYL2,THRA,TMOD1,BEST1,NUP214" Drug 922_UP celecoxib; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.02E-04 1.00E+00 1.91E-03 2.17E-02 49 189 "NDRG2,APC,ASCL1,ATP2B2,BCL7A,ST3GAL5,CHRNA4,B4GALT6,FADS2,ABI3BP,RCHY1,PDE4DIP,DZIP3,ARHGEF4,DBT,SPOCK3,DTNA,EDNRA,ST3GAL6,ZNF589,ERAP1,SIGLEC8,GRM1,RASSF8,DHX35,MGAT3,NF1,NNAT,NPTX1,NUMA1,PLTP,SIDT1,PTHLH,PTPRB,RAD52,PPM1E,ASAP3,EPN2,KANSL3,SLC20A2,SLC22A4,SOX3,CAMTA2,ZNF34,TRIO,RUNDC3B,TRPC1,VIPR2,REEP1" Drug 1606_UP Metergoline [17692-51-2]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "NDRG2,PPFIA1,ARNTL,ASPH,SYNJ2,OSGIN2,RAB28,CRMP1,FEZ2,FBXL5,SIDT2,EGR3,EPB41L2,VPS26C,EZH1,F3,C1orf61,SEMA4D,FLNC,TRMO,OGA,GFER,GRIK5,HMGCR,LSS,GIT1,SETD4,ENPP2,PLCB2,PLCD1,ZNF426,PTPA,VPS13C,PTX3,ATXN2,SGK1,AMBRA1,URGCP,MAPKBP1,WDTC1,EMC1,IQSEC2,THSD1,STXBP1,GSE1,MGRN1,TCF7L2,RBFOX2,REEP1,AAAS" Drug 4285_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "BRAP,APBB2,ALDH4A1,CBFA2T2,SEPT7,ZFYVE9,HOMER3,WHRN,HAPLN1,CRY2,PDE4DIP,CNTNAP2,SDC3,FAM131B,KIAA0513,RUSC2,FAM13A,RGS17,ETV1,ANKMY1,EZH1,TESK2,BAIAP2,FLT1,PDLIM5,FYN,SRCAP,POLL,SHISAL1,KCNMA1,KIF5C,PALM,PTPA,WDR25,TMEM231,RAB3IL1,RALGDS,SBF1,DOCK10,SMTN,SPTAN1,ZBTB43,TSPYL2,ELOVL4,ARHGEF9,ASTN2,KIAA1107,TNS1,LAT2,NDRG4" Drug 3308_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "KIDINS220,AK2,APC,PPP4R4,ATM,CFLAR,SGCE,CACNA1D,CAMK2B,CBFA2T2,FOXN3,CHM,CLU,CSF1,GREB1,RIMS2,RIPOR2,RIMS3,CTIF,HP1BP3,DTNB,DUSP9,MBNL2,VPS26C,FOXG1,POLL,ATXN2L,HLF,C2orf72,IL6ST,ITGAM,KCNN1,CDK14,C19orf57,PRKAR1B,PRKCB,MAPK8,KCTD17,RASA3,SNCA,SS18,PHLDB1,POPDC3,DMXL2,RPGRIP1L,KCNK12,ZNF74,PRDM10,GJC2,JPH3" Drug 3288_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "APAF1,APC,CDC14B,PPP4R4,SLC2A11,CFLAR,LDLRAD4,CBFA2T2,CDO1,CHM,SLIT2,TMEM59L,AKAP7,CSF1,NOS1AP,SRGAP3,DUSP9,SGK2,MBNL2,EIF4G2,PIPOX,ZNF589,CAMSAP1,GATM,SRCAP,GLYR1,IL11RA,KCNA4,TM6SF1,SLCO1C1,NNAT,NTRK2,CLDN11,PLTP,PAQR6,PPP1R9A,CXXC4,ZSWIM8,RBM26,SYN2,WSCD1,TRIM2,SYNE1,ICAM5,CHST5,TRPC1,LAT2,SLC30A3,NT5M,PLSCR4" Drug 2206_DN Finasteride [98319-26-7]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "NDRG2,MTUS1,MRTFA,AMPD3,BIN1,APP,MARK4,SGCE,C5,MYRF,CLCN4,HOMER3,USP6NL,SEC14L5,DBT,SGSM2,FEM1B,EFNA3,RASGRP2,F5,KAT8,EFCAB2,NBEA,GAB1,SRCAP,GRIK5,GSN,PADI2,LSS,MAP4,SCAMP5,GIT1,NPR2,NRGN,CEP41,KLK6,TMEM104,PTAFR,TCP11L1,FAM102A,ANKRD6,BTBD7,DOP1A,IZUMO4,ZC4H2,TCF7L2,PCDHGA10,TNNT1,CABIN1,URM1" Drug 4602_DN Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ASIC1,ACLY,MTUS1,TRMT9B,MARK4,SCAPER,MAP7,TAOK2,QKI,HOMER3,VCAN,SLITRK5,ARHGAP32,DBT,KIAA0753,RCAN1,RRAGB,ST3GAL6,ZNF589,ANKFY1,PDLIM5,ZNF276,HNMT,DIPK1A,MBD1,NFYA,RC3H2,PPP5C,PRKAR1B,WDR25,PSMD13,TTLL7,SH3BGR,ABLIM3,PEX26,COA1,SMARCA4,TAB2,SS18,VAMP1,ARHGEF9,EXOC7,IQCE,FBXW11,ARHGEF12,RBFOX2,HIRA,NSD2,UPF3A,MAP3K12" Drug 6710_UP Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "KIDINS220,GAS7,CADM3,IL33,MAP7,MTMR7,NRXN2,FAM149A,HAPLN1,CSF1,RGS6,PDE4DIP,PHF14,CTH,CTNND2,RIMS2,PITPNC1,DCT,MFAP3L,ST8SIA3,PLXNC1,FAM198B,AGAP2,GABRA3,ERAP1,GNG3,GRM7,GRM8,ICA1,LSS,AFDN,DDX25,PDE4B,SMOX,PPP1R1A,PPP5C,PTHLH,MARCH1,KLHDC8A,PNMA8A,TMEM206,EMID1,PKNOX2,SLC11A1,SOX2,ARHGAP26,SMG6,VIPR2,LAT2,GAN" Drug 2284_DN Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ASIC1,NDRG2,NME5,LTBP4,MRTFA,AMPD3,APBA2,SYNJ2,GYG2,CANX,RCBTB2,PLEKHB1,CNTN1,DCAF8,JAKMIP2,DUSP9,FGF12,C1orf61,ANKFY1,SRCAP,GLYR1,POLL,GRIK5,GSN,VWA5A,MBD1,KITLG,ADAM22,MYT1,NFYA,PDE3B,RETREG1,PLCD1,PPP5C,MAPK8,PTN,FAM120C,CEP97,ZNF365,ELMO2,SLN,LIMCH1,INKA2,PLCB1,TRIM2,VAV2,VLDLR,ZFP37,PRDM2,SENP7" Drug 5362_UP Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "AP2A2,CDC42BPA,PPFIA3,PDXK,ARHGDIG,BCL7A,BAIAP3,CARS,CDH10,CLOCK,CRY2,SDC3,PPP6R2,SMG7,EDN3,SIDT2,LRRC23,EZH1,BAIAP2,CAMKK2,GABRA2,DISC1,SEPT9,GFER,POLL,DHX35,KCNF1,IPO5,MDM4,ZNF862,POLG,TMEM104,RIPOR1,RGS12,RPS6KA2,SH3BP2,SLC2A5,SMARCC2,ZCCHC24,ZSWIM8,PLCB1,ARC,ARHGEF12,TRIO,ZKSCAN5,PLPPR2,VIPR2,PRDM2,EVI5,HPS4" Drug 5854_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ACTN1,BRAP,MTUS1,APBB2,APLP1,APP,PTBP2,KIAA1549L,HOMER3,TENM4,SOCS5,DZIP3,TOX,ZNF337,SPATA2,FBXL5,RHOBTB1,MED12,DYNC1I1,SUGP2,F8,ACSL4,FGF13,POMT1,GBX2,SESN1,COPS8,SLC2A6,MUM1,KIF2A,SCAMP5,MID1,PBX1,CCSER2,MAPK3,SNRK,NUDT11,KIRREL1,PAQR6,TMEM156,SH3BP2,ELMO2,SMARCA4,TMCC1,TNIK,FAM168A,FBXW11,PARD3,NAV3,KAT6A" Drug 3384_DN (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ABHD6,NME5,CDC42BPA,CNTNAP1,APC,EPB41L5,PPP4R4,ASPH,SCAPER,CBFA2T2,CLGN,STOML1,WHRN,SOCS5,NOS1AP,ATN1,FGFR1,SRCAP,MSL3,CACFD1,ATXN2L,VWA5A,SMAD1,MAP4,LYRM9,PCDH9,PDE3B,PLTP,MINDY2,PPP2R2B,MAPK10,GRAMD1C,ELOVL2,RAB3IL1,FAM184A,KCTD17,ZFHX4,RPS6KA2,PKNOX2,SMARCD3,KDM4B,EMC1,CAMTA2,PLCB1,EXOC7,SLC44A1,TPM2,TRPC1,WIPF1,ZFP37" Drug 4738_DN Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ARID1A,NDRG3,TRMT9B,BIN1,PLA2G4C,ATM,STX16,GYG2,CFAP410,NFS1,CLU,FADS2,QKI,WHRN,GREB1,EDRF1,DOCK4,MFAP3L,EDNRA,EFNB3,COQ7,DMTN,RRAGB,ACSL4,SEPT9,GCNT2,TDRKH,TJAP1,MMP16,NPTX1,PDE3B,MBOAT7,WDR25,PTK2,RAB3IL1,CEP97,ATXN7,ITSN1,ASAP3,ARHGAP26,CLSTN2,NSFL1C,PLCB1,ASTN2,EXOC7,TCF7,TNS2,THRA,TNS1,EPM2A" Drug 4763_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "AP2A2,NME5,LTBP4,AMH,APLP1,ATM,CFLAR,CA12,CAMK2G,ARHGAP33,LHX2,NCOR2,GREB1,RIMS2,NOS1AP,ATN1,STX2,DLC1,ST3GAL6,AGAP2,AFF2,GPR153,MSL3,GRM1,GRM8,KCNF1,MEF2C,ADAM22,ZNF862,MYT1,NNAT,PMS2,NKAIN1,ARHGEF10L,ZNF821,SLC6A8,CCDC88A,ZCCHC24,ZC3H13,SEMA4A,ROBO3,DMXL2,TCF7,SZT2,TMEM121,CABIN1,TNS1,ZMYND8,FAM155A,UPF3A" Drug 6621_UP Lysergol [602-85-7]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ABAT,PLA2G6,C1QTNF1,LTBP4,CAMK2B,RUNX1T1,CRLF1,CLCN4,CSF1R,VCAN,PDE4DIP,CNTNAP2,DAPK3,MFAP3L,EDN3,ZNF391,KIAA1109,FLT1,PRELID3A,FYB1,RUNDC3A,GSN,KCNB1,KCNC1,LAMA2,MAPT,AFF1,MX1,MYO7A,NCAM1,NF1,NPY,NOVA2,PCBP3,PCDH9,PDE4B,PGAM2,ZSCAN2,MARCH1,EMID1,SLC11A1,KIF21B,ZHX3,SPTB,SYT5,SEMA4A,OBSL1,ICAM5,RIMBP2,FLRT1" Drug 7492_DN semustine; Down 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ADRA1D,ADRB2,BIN1,APC,ARRB1,ALDH7A1,CHN1,CHRNA4,TAOK2,LHX2,COL9A3,NRG2,SDC3,DCAF4,RIMS3,RUSC2,EDNRA,ANKMY1,ANKFY1,GBX2,C1QL1,GPM6B,SYNPO,HNMT,KHK,KIF5C,GIT1,MX1,NUMA1,PFKFB2,PTX3,PID1,RAD51D,RAD52,MYH14,CSRNP3,WDR47,BTBD7,ZNF667,MYH15,SPATA7,SP4,CAND2,SPTB,TCF4,BEX4,TRPC1,VAV2,ZBTB38,SEMA3B" Drug 828_UP 5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "TRMT9B,EP400,APLP1,ALDH4A1,SYNJ2,LDLRAD4,REPS2,STOML1,SGSM2,CDON,DRD1,CELSR3,AASS,HSD17B14,RASGRP2,EFS,ANKMY1,F3,ST3GAL6,KIAA1109,BAIAP2,FYB1,SRCAP,LPAR4,GPR37,RASSF8,ITIH2,KCNH2,AFF1,MSR1,PDE3B,PIK3CD,POLG,PTPRB,PAQR6,RYR1,ZNF821,NLGN1,BTBD7,ZKSCAN3,SNCA,SOX2,SPTAN1,EPB41L3,PLCB1,ATP11A,ROBO3,IQCE,CRTC1,TK2" Drug 5904_UP AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ARID1A,NDRG2,ADD2,ADORA2A,SEMA6A,SEMA7A,APBB2,ASCL1,BRINP2,CACNA1I,CFAP410,P2RX6,CDH2,RAB33A,WHRN,CSF1R,ELMO1,RUSC2,MBNL2,DLC1,ZNF589,TPK1,DLL3,TRAF3IP2,GPER1,IFI16,KCNJ5,KCNN1,VWA5A,MDFI,MGAT3,ADAM22,PCSK1,LRP12,PPP5C,ZSCAN2,RAB3IL1,ZNF493,ZMAT4,RPS6KA2,RYR1,MRAS,SHANK2,IGSF9B,ZCCHC24,VAMP1,SYNE1,PSD3,LAT2,MVB12B" Drug 1860_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ASIC1,APBB2,APP,ASPH,ENTPD6,QKI,HOMER3,TBC1D5,DBN1,RCAN1,HIPK3,FRY,PTK2B,ZNF589,HBS1L,GART,COPS8,GLS,MAN1B1,KLC1,VWA5A,MAP4,MDM4,MKLN1,ZNF862,NF1,SETD4,P2RX7,GPR85,SERPINE2,POLG,C1orf109,RALGDS,MCMBP,FERMT1,PPP4R3A,COA1,DOP1A,MAPK8IP3,KANK1,VPS13A,THBS4,TK2,PIK3R5,CADM1,PLPPR2,ZBTB14,ZNF23,TRIM9,MAP3K12" Drug 1632_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ARID1A,AP2A2,PLA2G6,APBB2,ST3GAL5,SCAPER,CA4,CNOT8,ZFYVE9,CTH,SPOCK2,SMG7,OPTN,RBM12,EGFR,SORBS3,RRAGB,ARMCX1,INPP5K,GLS,POLL,GPR19,NR3C1,GRM1,ICA1,SCIN,MBD1,MIA2,NAP1L2,NOS1,NPPA,NUCB1,STRN3,SYTL2,SIDT1,WDR25,PTCH1,PLPPR1,BTBD7,WDTC1,CDK19,ZBTB43,NXT2,TRIM2,BEX4,SEZ6L,TRIO,TRPM2,ZKSCAN5,SPHK2" Drug 4391_DN Sparteine (-) [90-39-1]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ADORA1,BIN1,MARK4,SLC2A11,HAP1,CBFA2T2,B4GALT6,RAB28,SLC4A7,SH2B1,EXOG,E2F5,OPTN,ERCC2,FECH,PRKAG2,ANKFY1,DPYSL4,GAB1,SRCAP,C1QL1,GLS,GNAS,NR3C1,INPP1,KPNA5,KITLG,MMP16,ADAM22,CNOT4,RETREG1,LRP12,PTHLH,FNDC3A,PEX26,UNC5B,SPTAN1,SPART,LHPP,ELOVL4,VPS13A,AHCYL2,HIRA,PLPPR2,ZBTB14,ZNF24,EMSY,EVI5,HPS4,SSPN" Drug 5794_DN Methazolamide [554-57-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "BIN1,APOC1,PDE8B,CDC42,PLEKHB1,AKAP7,NRG2,SNPH,DAPK3,C2CD2L,FEM1B,MBNL2,RGS17,POMT1,CGREF1,DENND2A,SEPT9,PCDH17,BACH2,IL11RA,INPP5B,JAK2,MAPT,NDUFA5,NF1,ODF2,PBX1,NLE1,MAPK7,PTPRH,PTPRN2,RAB3A,RAP1GAP,BEND5,ZDHHC14,RGS7,KIRREL1,ZNF671,ATXN7,PPP1R9A,ASAP3,CCDC88A,MCF2L,TIAM1,TK2,UGT8,VIPR2,WIPF1,NDRG4,NAV3" Drug 6467_DN Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "AP2A2,SEMA6A,MRTFA,TRMT9B,AMPD3,APBA2,PLA2G4C,ATM,RIPK1,ADAM15,CDH10,CLU,SIPA1L1,ZNF337,HP1BP3,DLG3,EGFR,GPR153,GLS,PRRC2B,KCNF1,IPO5,LYRM9,NELL2,NF1,NFYA,PDE4B,LRP12,ELOVL2,TMEM231,KHDRBS2,MAPK12,SBF1,ATXN2,ZNF821,BCAN,FAM214B,SLC20A2,LIMCH1,TROVE2,ARC,ATP11A,TCF7,HEY1,TK2,CABIN1,HIRA,LMF1,ZNF74,SEMA3B" Drug 862_UP 5230742; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "DOC2A,EP400,PPFIA3,CACNA1D,ZFYVE9,AKAP6,EDRF1,TBC1D5,AASS,DMTN,F3,STRADA,FHL1,DPYSL4,FAM49B,GPR153,GAB1,ZNF44,CACFD1,GRM8,MAP4K5,HPCA,INPP5B,PACRG,MBD1,NNAT,NUMA1,PDE3B,RETREG1,PRKAR1B,SAMD9,ZSCAN32,ZSCAN2,ROM1,FNDC3A,FAM214B,BTBD7,TTC17,ZBTB43,THSD1,PLCB1,CRTC1,AHCYL2,AP4E1,TRPC1,LMF1,REEP1,PRDM2,NT5M,EVI5" Drug 3779_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.04E-04 1.00E+00 1.91E-03 2.17E-02 50 194 "ADRA1D,PLA2G6,CDC42BPA,APP,STX16,ADGRB2,MTMR2,CBFA2T2,CDC42,LHX2,ZFYVE9,PICK1,CNTNAP2,CDKL3,ETV1,TRMO,GLRB,GPM6B,HSF2,TJAP1,VWA5A,NF1,NFYA,CNOT4,PDE4D,NLE1,SLC25A23,RGS4,NEK11,ASAP3,PEX26,RBM34,TNIK,EMC1,ARHGAP26,ATP10B,COLGALT2,NXT2,EXOC7,TCF4,PSD3,CRTC1,DNAH7,TMPO,TNS1,XRCC4,SPHK2,REEP1,SCG2,DPF3" Drug CID000157688 vinflunine Stitch 2.05E-04 1.00E+00 1.91E-03 2.17E-02 19 52 "HEPH,EGFR,TUBD1,TUBB3,TUBB4A,TUBA8,GPR162,TUBA1C,TUBB2B,MAP6,MX1,ABCB1,MAPK8,PTK2,TUBB2A,TUBB1,ANKS1B,TUBA1A,EPM2A" Drug CID000072293 "phorbol 12,13-diacetate" Stitch 2.05E-04 1.00E+00 1.91E-03 2.17E-02 18 48 "CACNA2D1,SPAG9,FGF1,GABBR1,GRIA1,GRIA4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PRKCB,PRKCG,PSMA6,SNAP25,SYNE1" Drug 7020_DN Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG3,EP400,CDK10,C5,BTRC,CCNT1,CLCN3,C2CD2,NCOR1,SIPA1L1,DCAF8,KIAA0586,GIT2,SGSM2,DSCAM,DTNA,MAMLD1,OPTN,SUGP2,VPS26C,FGFR1,PDLIM5,ATP2C1,SYT17,NR3C1,RNFT2,HNMT,DHX35,KCNJ3,MAP4,NRGN,NUCB1,SMOX,SLC25A23,STRN3,TRAPPC13,ZFP30,AMBRA1,SYBU,IFT122,MAPKBP1,RAP1GAP2,LHPP,MTCL1,MCF2L,TRIM2,TSC2,UBTF,LMF1,SPHK2,FIP1L1" Drug 6334_UP Benzonatate [104-31-4]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "BIN1,SEMA4G,ALDH4A1,KIF1A,FGF17,SYNJ2,BAIAP3,CACNA2D1,MAP7,RUNX1T1,SYNGR3,SULT4A1,RAB26,PICK1,CNTN1,ENTPD4,AATK,PARD6A,ATN1,SIDT2,EFNA3,FAM13A,FOXG1,TRAF3IP2,HBS1L,SRCAP,AHDC1,ADAM28,GPM6A,HNMT,IL6ST,MYH3,LYRM9,PENK,PIK3R1,MINDY2,ENOX1,GAL3ST4,SUPT20H,ST6GAL1,EPN2,PKNOX2,ARHGEF40,IFT122,KDM4C,TK2,TMOD1,ZNF74,TFIP11,SEMA3B,NUP214" Drug 2231_DN Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG3,NDRG2,APBA2,SEMA4G,ARHGDIG,MTMR3,GYG2,C5,CDH10,DNAJB5,SLC4A7,PPP6R2,EDRF1,SEC14L5,ARMCX2,ZNF804A,MFAP3L,TMCC2,CDON,CELSR3,TESK2,ZNF589,SEPT9,GCNT2,COPS8,POLL,GSTM5,TJAP1,MAN2A2,MBD1,MSI1,CNOT4,PDE3B,SLC25A23,PTHLH,NEK11,FNDC3A,SOX3,EMC1,ARHGAP26,SPTAN1,LHPP,WSCD1,SLC44A1,TIAM1,CABIN1,TRIO,WIPF1,SPHK2,SYNC,SEMA3B" Drug 5670_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ACTN2,NDRG2,DOC2A,ASCL1,ATP1A2,AZGP1,CAMK2G,INA,CD86,DNAJB5,CNN3,CNR1,CRY2,SEC14L5,DOCK4,CTIF,DUSP9,ABCC9,ST8SIA3,CNNM1,EGFR,EPHB1,F5,OLFM1,FHL1,NSG1,GABRA2,RND1,RAB30,SYNPO,KCNH2,KCNJ5,KCNMA1,MDFI,NPTX1,CEP97,ZNF493,SH3BP2,SLC1A3,SLC11A1,SOX15,PLCB1,WSCD1,TRIM2,PCDHA6,TNFRSF1B,SPHK2,SEMA3B,SLC17A6,PARP11,SSPN" Drug 6794_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADCY6,ADRA1B,AGT,MARK4,BCL2L2,CFLAR,CA4,HAP1,CCK,CHRNB2,DNAJB5,JAKMIP2,CNIH3,PARD6A,ATN1,SIDT2,EFNB3,EGFR,REEP2,FHL1,GPR153,TDRKH,CACFD1,GRM1,TJAP1,KCNN1,MID1,NUMA1,SETD4,PIK3CD,PTAFR,ZSCAN2,KCNIP1,SBF1,NLGN1,SLC1A7,SMARCD3,LIMCH1,SNCA,TSPYL2,MAPK8IP3,ARHGEF9,WSCD1,CHST8,GPR161,ZNF34,FAM155A,PLPPR2,SEMA3B,KCNAB1,ITM2C" Drug 1727_DN Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ACADM,ADRB2,PPFIA1,SLC25A14,FOXN3,MAP4K4,RNF14,SOCS5,CTH,RUBCN,ZFYVE16,SPOCK2,DBN1,SPATA2,DCTN1,TRAPPC9,DMTF1,EGR3,KCTD3,ING4,EPB41L2,OGA,KTN1,MBD1,NACA,SETD4,OPA1,STRN3,LRP12,PMS2,PTPA,PPP2R5C,VPS13C,C12orf49,CLSTN1,SLC11A1,UNC5B,ZBTB43,SPART,ZNF302,SS18,STAU1,RGL1,DIP2A,AGTPBP1,WBP2,SSBP2,VIPR2,WRN,ZNF184,ST7" Drug 7552_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASPH,CFLAR,CA12,CAMK2B,KYAT1,JAM2,RAB33A,CLCN3,QKI,HOMER3,ARMC8,NCOR2,CSNK1E,JAKMIP2,ATN1,DTNA,FCF1,SORBS3,ZNF589,CAMSAP1,FOXG1,GPR153,OGA,GART,GNG4,NXPH3,TJAP1,IL6ST,KCNN1,MIA2,PDE3B,LRP12,PACSIN1,RIC8B,MYH14,TCP11L1,WLS,FBXO11,ANKRD6,CCDC88A,BTBD7,SNCA,SP4,STX1A,TRPC1,ZKSCAN5,VIPR2,SLC26A10,TFIP11,FIP1L1,SMIM8" Drug 6355_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ARID1A,MTUS1,BIN1,ANK1,KIF1A,ST3GAL5,CACNA1G,KRIT1,CDH8,FOXN3,B4GALT6,CLCN3,CLCN4,DNAJB5,NCOR2,CTNND2,CTIF,ATN1,DTNA,SIDT2,EFNA3,MTSS1L,FGFR1,FLT1,DENND2A,GAD1,SYT17,CNTRL,NR3C1,SHISAL1,SCIN,MIA2,ADAM22,NUMA1,NLE1,RC3H2,PPARA,PTCH1,PTPRH,GAL3ST4,TCP11L1,ATXN1,FBXO11,CDK19,ACSBG1,TBCEL,TIAM1,WIPF1,XRCC4,ST7,DPF3" Drug 2363_UP Proglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "MTUS1,NR0B1,PLA2G6,APBB2,SEMA4G,CDK13,BACH1,KSR1,BMP7,MTMR3,MAP7,CD86,CDH2,CRY2,KIAA0753,C2CD2L,DTNA,EFNB3,MRNIP,FAM198B,FOXG1,PRELID3A,MYOZ2,GATM,GPR162,GNAL,GPD1,SPACA9,CELF3,HNMT,VWA5A,MYO6,ZNF862,NF1,PTCH1,RIPOR1,ZCWPW1,SEC61A2,FOXRED2,SLC1A7,EPN2,SLC15A2,BTBD7,IQSEC2,ZC4H2,TGFBR3,KCNK12,SYNC,EVI5,SLC17A7,SENP7" Drug 3606_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ARID1A,ADORA1,SPARCL1,SYT13,ANK1,APOC1,MARK4,LDLRAD4,INA,CPS1,PYGO1,KLHL3,GSDME,EDN1,SGK2,FRY,EFNB3,EGR3,DLC1,FOLR2,GAD2,HPSE2,HTR2A,SHISAL1,KIF5A,KIT,MAPT,MN1,MYCN,MYO7A,NELL2,NF1,NNAT,TREM2,PALM,SEPT4,PACSIN1,POU3F4,ELOVL2,RAD52,SLC6A9,SOX10,PEG10,ARC,SYN2,ADGRL3,SZT2,PCDHGA1,TPM2,TTPA,SEMA3B" Drug 1679_UP Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "OSBPL1A,MRTFA,APBB2,MARK4,ADAM23,RAB28,ZFYVE9,HOMER3,BAG4,CSF1,GPRASP1,SMG7,SGSM2,CDON,DTNA,NCALD,SEMA4D,CGREF1,MALT1,SPACA9,INPP5B,KHK,KIF5C,MAP4,MBP,MKLN1,MMP16,ZNF862,NAP1L2,NF1,NTRK2,NLE1,MED1,ELOVL2,RAD52,FNDC3A,ZCCHC24,SPTAN1,CDK19,ZBTB43,NXT2,AJAP1,PLCB1,TCF7L2,TRIM2,AP4E1,ZNF34,VIPR2,REEP1,PHTF2,SSPN" Drug 920_DN 5-aza-2′-deoxycytidine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASPHD1,ABHD6,NDRG2,ADD3,AP2A2,BIN1,ST3GAL5,SPAG9,SCARB1,REPS2,TAOK2,LHX2,QKI,GIT2,SLC12A6,DSCAM,DTNA,VPS13B,DMTN,ANKMY1,TAOK3,DLC1,FHL1,SYT17,POLL,CLASRP,CCSER2,POLG,MINDY2,SAMD9,TMEM104,ATXN1,ASAP3,FUZ,BTBD7,SLC20A2,ZHX3,ERC1,MAPK8IP3,DIP2A,TACC1,FRYL,AHCYL2,TMEM121,ZNF34,CABIN1,CADM1,VGF,LMF1,ZNF74,MVB12B" Drug 6328_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "CDC42BPA,DNAH17,ALDH4A1,BMP7,CACNA1G,CFAP410,LHX2,PICK1,AATK,CSNK1E,DTNA,EFNA3,EFNB3,FAM13A,PLXNC1,CORO2B,ST3GAL6,OGA,SEPT9,GFER,HTATSF1,GNAS,PRUNE2,GRM1,GUCY1A1,KLF12,KCNB1,KIFC3,MGAT3,NDUFA5,PDE4D,MINDY2,PTPRN2,C1orf54,RGS4,FRMPD1,SOX2,PHLDB1,ASTN2,KIAA1107,WSCD1,DNAH7,THRA,TRIO,TSC2,TUBB1,VGF,VIPR2,VLDLR,XRCC4,KCNAB1" Drug 6069_DN Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ALCAM,MRTFA,APBA2,KCNAB2,APBB2,ASPH,ALDH4A1,CSF1R,FAM169A,DZIP3,SDC3,APPL1,RIMS2,PPP6R2,GIT2,DTNA,TOM1,EFNA3,MBNL2,FAM198B,ZNF589,FGFR1,BAIAP2,IQCG,SEMA4D,USP19,TXNL4A,GRB10,HNMT,INPP5B,ITPKB,KPNA5,MAPT,MATK,MYO9A,PDE3B,RETREG1,POLG,WDR25,NKAIN1,RALGDS,WLS,ITSN1,SMTN,SMARCD3,EMC1,TACC1,AHCYL2,TMEM121,ZKSCAN5,VIPR2" Drug 3137_UP Tiletamine hydrochloride; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ABHD6,AMPH,CNTNAP1,CDK10,ARHGDIG,MYRF,CHN2,PLAA,COL9A3,ABI3BP,CRYM,CSF1,KLHL3,NTM,DLG3,CDON,DSCAM,DTNA,E2F5,EEF1A2,SORBS3,C3orf18,LRRC23,ETV1,F5,GABRA2,GAP43,ALDH1L1,GNAL,GPR22,GRIK5,HRH3,C2orf72,SCIN,MAP4,MMP16,OPRL1,FAM120C,RGS12,GALNT10,PREX2,LIMS2,PKNOX2,SNCA,SP4,CRTC1,TJP1,DAAM2,UBE3A,SCG2,PAK5" Drug 7275_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "PPP4R4,BAIAP3,MAP7,CHM,CHN2,CHRNA4,LHX2,NRXN3,ZFYVE9,CABP1,BAG4,CTNND2,ARHGAP24,SMG7,CDON,EDIL3,AASS,MRNIP,REEP2,ZNF44,GLRB,GPR75,GLS,POLL,GRK4,CNTRL,GUCY1B1,LIG4,MARK3,MBD1,MGAT3,MOBP,MX1,NF1,NPR2,SLC11A2,NUMA1,ENPP2,PRPH,GON4L,KHDRBS2,AMBRA1,SLC1A3,SLC2A5,FNBP1,SPTAN1,SS18,CEP68,RPGRIP1L,SYNE1,TRPC1" Drug 6126_DN Natamycin [7681-93-8]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASIC1,MTUS1,AMPD2,PKP4,CDK13,CAPRIN2,N4BP2L1,SCAPER,CAPN3,TMEM184B,ARHGEF10,SLITRK5,PPP1R16B,DCAF8,SMG7,RCAN1,DTNA,FAM13A,NCALD,ERAP1,WASF3,GPR22,ATXN2L,VWA5A,NFYA,PDE4A,PDE4B,PDE4D,PTPA,RIPOR1,PID1,GSTCD,CLIP1,RASA3,FAM214B,KBTBD4,SNCA,WDTC1,ZCCHC24,ITPRID2,NCDN,SYT11,ARHGEF9,ZNF34,R3HDM1,RBFOX2,ZKSCAN5,LAT2,ZBTB38,PHTF2,NLRP3" Drug 3205_DN Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "AMPD2,AMT,APP,RGS20,STX16,USP2,SCARB1,QKI,WHRN,CHD1L,SOCS5,DAPK3,DBT,FBXL5,RABGAP1L,FCF1,EFNA3,HSD17B14,STX2,VPS26C,KIAA1109,GABRA2,GART,RASSF8,ATXN2L,AGFG1,HSD17B1,KCNH2,KCNJ3,MAP4,MDM4,KITLG,ADAM22,NEK1,NF1,LRP12,PPP5C,PEX5,GTDC1,NEK11,KDM4C,UNC5B,NXT2,TACC1,SEMA4A,TBL1X,ZNF34,KAT6B,NPL,MAP3K12,UBE3B" Drug 6470_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "PLA2G6,SEMA6A,SRPX,MRTFA,AMH,APC,APP,LDLRAD4,SPAG9,PLAA,NRG2,EDRF1,MFAP3L,TMCC2,DTNA,EDNRA,FEM1B,SUGP2,EGFR,SORBS3,ANKMY1,ATP8A1,DISC1,BTN2A1,HSF2,INPP1,KCNH2,IPO5,NF1,NPTX1,PLXNB1,PPARA,MAPK7,SUSD4,KHDRBS2,SAFB,BCAN,SYBU,FAM214B,ZKSCAN3,DOK5,TROVE2,NXT2,MAPK8IP3,STX1A,TCF7L2,PSD3,THRA,TK2,CABIN1,PLPPR2" Drug 4330_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "SYN3,ADCY2,ADRA1D,FAM135A,AMPH,ARHGDIG,KIF1A,CACNB2,LARGE1,CHI3L2,MYRIP,CNTNAP2,SPOCK2,ATN1,DSCAM,REEP2,DLC1,FGF1,TBR1,IQGAP2,ATP8A2,GFRA1,MCHR1,GRIK2,ADAMTS13,KCNJ9,MMP16,NF1,NNAT,NTRK2,PAK3,PIK3R1,RFX2,RGS7,TMEM206,PRR5L,SEMA6D,SLC1A7,SLCO1A2,CXXC4,ZHX3,HECW1,IQSEC2,RBM26,ATP10B,PLCB1,TAC3,CRTC1,TPM3,FLRT2,SF1" Drug 4691_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "BIN1,APC,CDK10,MARK4,SCAPER,MTMR3,C5,KYAT1,SLIT2,CRY2,DZIP3,CTIF,JAKMIP2,SMG7,DSCAM,LRRC23,STX2,ANKMY1,ACSL4,ZNF589,FGFR1,FHL1,CAMKK2,GFER,POLL,GOLGB1,CNTRL,GRM8,KPNA5,NEUROD1,SMIM7,RAB3IL1,FBXW7,ABLIM3,SOX2,ZCCHC24,NCDN,STX1A,IQCE,TBL1X,TCF7L2,CABIN1,HIRA,VAV2,VIPR2,VLDLR,KCNK12,DNALI1,EVI5,KCNAB1,NUP214" Drug 5433_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG2,ADRA1D,ALCAM,LTBP4,APC,EPB41L5,SCAPER,C5,CLCN3,SH2B1,SDC3,MAML1,GIT2,HP1BP3,RABGAP1L,DSCAM,PLXNC1,EIF4G2,HSD17B14,ANKMY1,FGFR1,SEMA4D,DISC1,RAB30,POLL,GPER1,ATXN2L,HNMT,KIF2A,KPNA5,MPP2,ADAM22,LYRM9,NDUFA5,SETD4,MAPK7,GON4L,TMEM104,PTHLH,MSANTD2,ASAP3,PPP4R3A,EMC1,INKA2,VAMP1,PLCB1,ATP11A,EXOC7,TCF7L2,TRPC1,SPHK2" Drug 5925_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "MTUS1,TRMT9B,APP,ALDH4A1,SCAPER,CACNA1I,LDLRAD4,CAMK2B,NEURL1,QKI,BAG4,ABCG1,SNCAIP,CSF1R,CTNND2,MFAP3L,CDON,SORBS3,ING4,FGF12,FOXG1,SORBS1,GABRA2,RAB30,GRIK5,PTGDR2,ICA1,MSI1,NOVA1,KCNK10,PDE4A,LRP12,PRKAR1B,ZSCAN2,GAL3ST4,KCTD17,ZFHX4,ROM1,ZFP30,SH3GL3,SLC4A3,PREX2,LIMS2,PKNOX2,RBM34,TSNAXIP1,UNC5B,FAM155A,VAV2,DNALI1,RNF170" Drug 402_DN rapamycin; Down 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "RBM10,BRAP,APBA2,DGKD,CDK10,ARNTL,ASCL1,MPDZ,CDC27,SLIT2,TJP2,CSNK1E,PDE4DIP,ECE2,EFNA3,RGS17,SPEG,EZH1,FGFR3,CAMKK2,GNAO1,SLC2A6,C2orf72,KHK,L1CAM,MBD1,ADAM22,PLCD1,SMIM7,MAPK8,NKAIN1,FOXRED2,SAFB,SGK1,ITSN1,KBTBD4,ELMO2,ZCCHC24,EMC1,ZC3H13,ZBTB43,CLSTN2,SEPT8,PRRC2C,IQCE,TBL1X,TMPO,TRIO,GDPD5,MPPE1,ST7" Drug 3345_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADORA2A,APBA2,DGKD,MARK4,FADS2,SH2B1,CSF1,ARHGEF10,PDE4DIP,JAKMIP2,MFAP3L,KBTBD11,EFNA3,ING4,STX2,FGFR1,DPYSL4,GPR153,SEPT9,RASSF8,VWA5A,GIT1,MYO7A,MAPK7,MAPK8,ELOVL2,ZSCAN32,RAD52,ZCWPW1,CCDC25,TCP11L1,RPS6KA2,IL17RB,ASAP3,FNDC3A,SYBU,PKNOX2,SHANK2,ELMO2,MAPK8IP3,ATP11A,SMG6,KIAA0930,TCF7L2,SZT2,CRTC1,PCDHA6,KAT6B,TRPC1,NSD2,SSPN" Drug 1442_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "AP2A2,SYT13,APC,CDC14B,SLC4A4,RIPK1,RGS11,CAST,CHRNB2,SEC31B,VCAN,DAPK3,SIRPA,HP1BP3,TRAPPC9,F8,OLFM1,PRKAG2,FOXM1,ATP2C1,CELF1,HBS1L,GLS,LILRB4,ATXN2L,AGBL5,ITGAV,KCNJ3,MAP4,MEF2C,SETD4,CCSER2,POLG,SIDT1,ARID4A,BSDC1,SLC2A5,KBTBD4,ELMO2,MAPKBP1,POGZ,MLC1,ZMAT3,TLL2,TMOD1,TPM3,TSC2,VGF,NSD2,NT5M,DPF3" Drug 3381_DN Niacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "BIN1,APC,FAM131A,MARK4,NUMB,BCL7A,BAIAP3,CA4,ZFYVE9,STOML1,WHRN,PHF14,PPP6R2,GIT2,ATN1,STX2,F3,PDLIM5,PRELID3A,HBS1L,SEPT9,IL6R,KCNJ5,SMAD1,MATK,CDK18,STRN3,MED1,PPP3CC,PRKAR1B,MAPK10,GRAMD1C,WDR25,TRIM68,TCP11L1,RASA3,SHANK2,SMARCD3,KDM4B,ZCCHC24,ZHX3,EMC1,CDK19,TBCEL,SMG6,PSD3,TPM2,PDIA2,VGF,VIPR2,EMSY" Drug 6950_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ABHD6,FAM131A,SCAPER,CA12,MAP4K4,ARMC8,CRY2,NCOR1,ABCG1,PPP6R2,ZNF337,DBT,MFAP3L,KIAA0753,C2CD2L,LYPD1,EFNB3,IRAK4,MTSS1L,INPP5K,KCNMB4,GRB10,ATXN2L,KCNF1,OXTR,PDE3B,ZSCAN32,RAB3A,RALGDS,ZCWPW1,GTDC1,RPS6KA2,GALNT10,FERMT1,ABLIM3,EPN2,SMARCC2,KDM4B,EMC1,ELOVL4,NSFL1C,ARHGEF9,ASTN2,TBL1X,KAT6B,SSBP2,HIRA,VGF,LMF1,MAP3K12,GAN" Drug 3061_UP Felbinac [5728-52-9]; Up 200; 18.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ACHE,ADCY8,TRMT9B,CDC42BPA,ANK2,MPDZ,CACNA1G,BAIAP3,CACNB4,KALRN,RUNX1T1,USP2,ENTPD2,DLGAP1,CHI3L2,NRXN2,TMEM59L,NRG2,CREB5,CRYBB1,PDE4DIP,BRINP1,EDN1,SRPK3,VPS13B,ATP8A1,AGAP2,GALR1,SIGLEC8,GPR75,GNAL,GPR37,GRIA1,GPR45,HNMT,HTR5A,KCNC1,KCND3,ADAM11,MYH7,DUSP26,RASGRF1,ASAP3,PALLD,SOX10,DBNDD2,ARC,TCF7L2,AP4E1,TK2,LMF1" Drug 1502_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASIC1,ADD1,KIDINS220,DOC2A,EPB41L5,CFLAR,CFAP410,CACNB2,ARHGEF1,PLEKHB1,FADS2,HOMER3,CRY2,ABCG1,CSF1R,CTNND2,MAML1,FBXL5,TRAPPC9,SLC12A6,RCAN1,ZNF589,SEMA4D,FAM49B,TXNL4A,FERMT2,HNMT,ITPKB,MIA2,NDUFA5,NF1,NPR2,SLC25A23,MAPK7,SIDT1,TMEM104,RIPOR1,FOXRED2,FERMT1,SLC6A8,BTBD7,WDTC1,LHPP,PHLDB1,ATP11A,PDLIM2,AHCYL2,PARD3,VAV2,VGF,REEP1" Drug 6935_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASPHD1,ABHD6,AP2A2,SEMA6A,BIN1,MARK4,BTRC,CAMK2A,HIP1R,LHX2,FAM149A,FEZ1,PDE4DIP,FAM169A,NOS1AP,KIAA0586,USH1C,FHL1,OGA,GAD1,GFER,GNAL,LPAR4,GRB10,DHX35,MAPT,MPP2,PRRX1,PPP2R2B,ARID4A,RGS3,EMID1,SEC14L1,LIMS2,FAM214B,ELMO2,SLC20A2,KDM4B,SOX10,UNC5B,SPTAN1,IQSEC2,CLSTN2,ANKRD12,WDR7,TMEM121,TMOD1,GDPD5,NAV2,WIPF2,TIGD6" Drug 2153_UP Sulmazole [73384-60-8]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADD2,CDC42BPA,APP,GYG2,BTRC,THSD7A,MAP7,CLGN,TAOK2,NMT2,CRY2,CSF1,PHC2,HIPK3,EIF1,STX2,CEND1,ATP8A1,FGFR1,DENND2A,SESN1,GNG3,GRM1,NXPH3,DHX35,IL11RA,KIF5C,LSS,MAP4,ZNF862,PFKFB4,CAMKV,PLEC,RIPOR1,ZMAT4,RFX2,SMARCD3,ZC3H13,CAMSAP2,TBCEL,SYNE1,SLC35G2,HIF3A,ATP13A2,SLC13A3,MKRN3,SPHK2,EMSY,PCBP4,FZD3,MARCH8" Drug 3341_DN Reserpine [50-55-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "APBB2,CDK10,ASPH,ATM,SLC4A4,BTRC,ADGRG1,CLU,CRY2,SDC3,PPP6R2,DCAF8,MAML1,RABGAP1L,DTNA,SIDT2,EFNA3,EIF5,ING4,BAIAP2,TRMO,GLS,GOLGB1,CACFD1,BTN2A1,IL6ST,KCNJ3,MMP16,NF1,CNOT4,PPP5C,PTN,RET,RPS6KA2,SUPT20H,ABLIM3,SLC6A8,BTBD7,TMCC1,RBM34,THSD1,NCDN,PHLDB1,SEMA4A,PCDHA6,TMEM121,TK2,HIRA,ZNF23,EVI5,WIPF2" Drug 1808_UP Acetazolamide [59-66-5]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ACLY,KIDINS220,APP,ARHGAP5,ASPH,MPDZ,ARHGEF7,C5,CA12,CBFA2T2,CLCN4,CLTB,AKAP7,CREM,NCOR1,DZIP3,DCAF8,MATR3,HP1BP3,ETV1,IQCG,GPR37,CNTRL,ACOT7,HNMT,JAK2,MBNL1,MTR,NASP,PIK3R1,ZFYVE21,REV3L,TTLL7,HSPA4L,SPTAN1,TAB2,CAMTA2,SS18,ARHGEF9,TNS2,DICER1,TIMP4,BEX4,R3HDM1,UBE3A,BCL2L13,VIPR2,NSD2,XRCC4,TFIP11,EVI5" Drug 7294_UP Imipenem [74431-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "SERPINA3,GAS7,APP,CDK13,ALDH4A1,KIF1A,MYRF,CAMK2B,TAOK2,RAB26,CNTNAP2,LYPD1,SPOCK3,DTNA,SIDT2,REEP2,EFEMP1,TPK1,PRELID3A,GAD1,GPR17,GRIK5,ATXN2L,INPP5B,KHK,KIFC3,MX1,PALM,WDR25,PEX5,RIPOR1,ZCWPW1,ZNF331,SCG5,ARHGAP26,SPTAN1,LHPP,THSD1,SYT11,ZFR2,KAZN,KIAA1107,SYNE1,CRTC1,CABIN1,TRIO,TRPM2,LMF1,PRDM2,NT5M,MPPE1" Drug 1623_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG3,NDRG2,ADD2,CNTNAP1,APBB2,SHROOM2,CADM3,CBFA2T2,IQCK,NCOR1,PPP6R2,CYBB,SPOCK2,SIDT2,CEND1,F3,FGFR1,GPR153,NSG1,HBS1L,ALDH1L1,TDRKH,LILRA2,PADI2,NXPH3,TJAP1,KCNB1,MPP2,GIT1,KCTD15,PLEC,POLG,MAPK10,PRPH,RFX5,TMEM156,ATXN2,SH3BP2,EPN2,FAM214B,CCDC88A,SPTB,NXT2,EXOC7,MGRN1,TCF7L2,ZMAT3,WBP2,TMPRSS5,VGF,ST7" Drug 6136_UP Trifluridine [70-00-8]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "APBB2,EPB41L5,APOC1,ARHGDIG,DDX3Y,ATP2B2,NRP2,CACNA1G,LDLRAD4,BTRC,MAP7,LARGE1,SLIT2,CNTFR,CREM,ABCG1,BRINP1,EGR3,PLEKHA1,FGF1,FHL1,KHDRBS3,NSG1,GPM6A,ICA1,KHK,MBNL1,CD200,MSI1,MYBPC1,NF1,NRCAM,DUSP26,PLTP,SEPT4,PPP5C,WDR25,RGS12,CARF,ROM1,SH3GL3,FRMPD1,ZNF365,SLC1A7,SLC20A2,TMCC1,PHLDB1,DMXL2,TRIM2,AMACR,PRDM10" Drug 4_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 1000uM; MCF7; HG-U133A" Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADARB2,BIN1,GAS7,SYNJ2,MTMR2,SCARB1,CD38,TJP2,PICK1,NCOR2,PDE4DIP,INTS1,ARMCX2,ARNT2,ABI1,EFNB3,ING4,FGFR1,POMT1,RASL10A,ATP2C1,GJB1,RUNDC3A,GRM8,NCKAP1L,HSF2,KCNJ5,LAMA2,MBP,ADAM22,FXYD6,NELL2,NF1,NNAT,NTRK3,PHKG1,C19orf57,PTH1R,PTPRN2,SCNN1D,SCN3B,ZCCHC24,SSTR2,TBL1X,WDR7,OBSL1,TNS2,PARD3,TUB,SLC13A3,MVB12B" Drug 4735_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "DPF1,ASPHD1,APC,APOC1,CDK13,CFLAR,SCAPER,EDRF1,ARHGAP24,RIMS3,EDNRB,EGFR,ELAVL2,C3orf18,SPEG,PTK2B,FGF13,FGFR1,PDLIM5,PRELID3A,GPR153,DISC1,PCDH17,GPM6B,ATXN2L,KCNH2,KCNN1,KCNQ3,MATN3,AFDN,ADAM22,P2RY13,NF1,NPR2,EPN1,TNPO2,MINDY2,MAPK7,FAM214B,FAIM2,ZCCHC24,TSPYL2,NPAS3,AJAP1,POPDC3,SLC19A3,TGFBR3,WIPF1,LAT2,SYNC,MVB12B" Drug 7163_UP Suxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG3,ADCY6,MRTFA,DOC2A,FAM131A,ALDH4A1,ATM,SLC2A11,CFLAR,NEURL1,CDC42,CNTFR,HDAC4,SPOCK3,RABGAP1L,TRAPPC9,DSCAM,ST8SIA3,DMTN,KIAA1109,PRUNE2,GPM6B,ELOVL5,KCNH2,MAP4,MMP16,ZNF862,NNAT,PLEC,SAMD9,GON4L,PTAFR,PEX5,TMEM231,RAD52,PPP1R9A,FAM214B,SNCA,THSD1,PHLDB1,ARC,SEMA4A,DOCK9,AHCYL2,TMOD1,CA14,ZBTB14,MPPE1,UBE3B,NUP214,SSPN" Drug 7019_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADRA1D,NME5,C1QTNF1,ALCAM,SRPX,MRTFA,AMT,ARHGDIG,SLC4A4,CFLAR,SCAPER,MTMR3,CACNA1G,CFAP410,CBFA2T2,RCHY1,ENTPD4,FEZ1,MFAP3L,EFNB3,EIF4G2,ING4,FGFR1,DPYSL4,FAM49B,GPR153,GPR45,ELOVL5,INPP5B,MATK,MDM4,MYCN,NF1,NNAT,PDE3B,PLTP,PEX5,EMID1,PAQR6,FBXO11,SMTN,KANSL3,ERC1,MCF2L,SMG6,KIAA0930,PCDHA5,AHCYL2,CHST5,ZNF45,PLSCR4" Drug 2989_DN Benzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG2,AGT,PLA2G6,ANK3,ADAM15,CACNB4,SLC16A4,CBFA2T2,DNAJB5,NRG2,SLITRK5,CTNND1,ZNF337,BRINP1,DSCAM,TOM1,E2F5,SIDT2,RASGRP2,DLC1,EFCAB2,ADAM28,PRUNE2,LILRA2,MAPT,PTN,PTPRB,RAB3A,RAB3IL1,TCP11L1,FRMPD1,ANKRD6,EPN2,MYH15,SOX2,NCDN,SYT5,CAMSAP2,KIAA1107,DMXL2,TCF7,TCF7L2,SZT2,DOCK9,RBFOX2,CDK20,TRO,BEST1,LMF1,SEMA3B,PCBP4" Drug 6080_UP Butirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "C1QTNF1,ANK1,ARHGDIG,ASCL1,BRINP2,ALDH7A1,KALRN,ENTPD2,CDH2,ABI3BP,ARHGEF10,ATRNL1,SPOCK2,SV2A,AASS,OLIG2,ZMYND10,FOLR2,GPR153,GATM,CNTRL,NR3C1,GUCY1A2,GUCY1B1,SHISAL1,C2orf72,MGAT3,TAGLN3,MYT1,P2RY1,CDK18,PFKFB2,PGAM2,PILRA,POU3F4,PPP1R1A,TRIM68,ZFHX4,KLHDC8A,RPH3A,SLN,LIMCH1,UNC5B,ZBTB43,ZEB1,PCDHGB6,CRTC1,TMOD1,R3HDM1,PLPPR2,XRCC4" Drug 2555_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADD2,KIDINS220,AP2A2,AMH,PKP4,CCDC181,ATP2A2,ATP6V0A1,RHBDL1,CLGN,CHI3L2,SULT4A1,CSNK1E,CNTNAP2,DZIP3,RIMS2,TMCC2,ING4,C3orf18,PTK2B,ZNF589,PCDH17,GPD2,PTGDR2,SYNPO,KIF5C,L1CAM,MDFI,NAP1L2,NCAM1,NRCAM,PDE4A,PLCD1,SLC25A23,MAPK8,CNTLN,ZMAT4,RGS12,ZNF821,SLC9A5,SLC11A1,SPTB,ATP10B,ARHGEF9,CUX2,PCDHGB6,PCDHGA10,TRPS1,FLRT1,PAK5,SSPN" Drug 7020_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADCY6,ADRA1D,APBB2,CACNA1D,SLC25A14,SOCS6,CHRNB2,FAM189A2,COL9A2,FEZ1,HDAC9,SGSM2,DTNA,PHF20L1,EPB41L2,CORO2B,FECH,BAIAP2,PRKAG2,FHL1,DPYSL4,GALC,IL6ST,NF1,SLC11A2,SETD4,PLXNB1,MED1,PRODH,ELOVL2,RIPOR1,ZDHHC14,RGS10,RGS12,MYH14,NEK11,FBXW7,FOXRED2,SBF1,PEX26,SPTAN1,THSD1,INKA2,AHCYL2,TEX15,PIK3R5,TRPC1,FAM155A,VLDLR,KCNK12,AP3B2" Drug 6550_UP PHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "BRAP,ALCAM,AMPD3,BIN1,CAMK2B,ARHGEF1,FOXN3,CHRNB2,CLU,AKAP7,ABCG1,LRIG1,MFAP3L,RUSC2,SMG7,DTNB,TOM1,APH1A,C3orf18,MTSS1L,NCALD,DPYSL4,INPP5K,GNG4,GPER1,GRB10,DHX35,ICA1,MOBP,MBOAT7,FAM120C,FBXW7,KCNIP1,PPP1R9A,FERMT1,DOCK10,BCAN,EPN2,KDM4B,ZCCHC24,THSD1,TTBK2,SEMA4A,DMXL2,BEX4,HIRA,LMF1,LAT2,FAM13C,KAT6A,SSPN" Drug 6816_UP Dacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "FZD9,BEGAIN,AMT,APAF1,APLP1,SEMA4G,ALDH7A1,ADGRB3,CACNA1A,HAP1,ARHGAP33,CBARP,SLIT2,CLU,RABGAP1L,EDNRA,SGK2,MBNL2,ERCC2,REEP2,KIAA1109,FGF13,FYB1,ALDH1L1,GCNT2,ADAM28,RUNDC3A,GNAL,GPM6B,SPACA9,GRM1,ICA1,KCND3,MYH6,ZNF862,NOVA2,CDK18,ENPP2,PFKFB2,PPARA,MYH14,KLHDC8A,MRAS,SH3GL3,FNDC3A,LIMS2,CCDC88A,ZCCHC24,CDK19,PARP11,KAT6A" Drug 4600_DN Iocetamic acid [16034-77-8]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NME5,MRTFA,BIN1,CNTNAP1,ARHGDIG,ADGRB2,NRP2,BAIAP3,CBFA2T2,SYNGR3,MAGI1,PLEKHB1,HOMER3,CSF1,CSF1R,EDNRA,SIDT2,PRELID3A,MSL3,GRK4,GRIK2,GRM1,HLF,ITPKA,KCNJ4,KCNN1,MDFI,MX1,NOVA1,OPCML,PAK3,PDE4B,PIK3R1,PLXNB1,SAMD9,APTX,RAD52,ZCWPW1,RPS6KA2,ZFP30,DZIP1,ZNF334,WDTC1,BEX1,RPGRIP1L,ZMYND8,VGF,VIPR2,WIPF1,LAT2,KCNAB1" Drug 5986_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "TKTL1,GAS7,APOC1,APP,RGS20,DGKI,QKI,NECTIN3,CRY2,DCAF4,DMPK,HIPK3,EFNB3,EBI3,PLXNC1,TNK2,DENND4A,PRELID3A,FYB1,GALC,ALDH1L1,PCLO,GRIK5,GSN,KCNH1,KCNN1,LSS,MAPT,MDM4,MSI1,NNAT,NTRK2,CDIP1,GRAMD1C,ZSCAN32,PTX3,ZSCAN2,C1orf54,KHDRBS2,ZDHHC14,ZNF821,SH3BP2,PPP4R3A,SLC11A1,TSNAXIP1,ZNF423,CLSTN2,DOCK9,VGF,NT5M,DNALI1" Drug 4847_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "TRMT9B,BIN1,SEMA7A,ATP1A3,SLC4A4,ALDH7A1,ADAM23,AZGP1,BACH1,MTMR3,DLGAP1,PLAA,SULT4A1,HAPLN1,AATK,RIMS2,EDRF1,RCAN1,PLXNC1,CDKL3,CEND1,ZNF44,SIGLEC8,GLYR1,TOX3,GRM3,GRM8,KLF12,TJAP1,ITIH2,KCND3,KCNMA1,KHK,ADAM22,NEFM,SERPINE2,GDPD2,C1orf54,NLGN1,SLC11A1,ZC3H13,SS18,ACSBG1,VAMP1,CHST8,TK2,TNS1,CHST5,SLC30A3,SCG2,DPF3" Drug 2498_UP Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ASIC2,BEGAIN,AMPD3,PKP4,SEMA4G,ARHGDIG,ASCL1,CACNA1I,CACNA1G,MAP7,SCARB1,CDH2,ZFYVE9,RAB26,CREM,RIMS2,DBT,DNAJC6,MAGI2,EXOG,DSCAM,EDNRA,HIPK3,APC2,AGAP2,CAMKK2,GATM,GPM6B,LILRA2,GPR22,JAK2,KCNN1,NF1,NINJ2,NPPA,NPR2,PDE4A,PDE4D,PPARA,PTH1R,RFX2,TCP11L1,LIMS2,SHANK2,SOX10,DOCK9,ARHGEF12,ATP13A2,CABIN1,RBFOX2,SLC17A7" Drug 2442_DN Calciferol [50-14-6]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "BIN1,CDC42BPA,APOC1,APP,LDLRAD4,HIP1R,QKI,IQCK,ARMC8,CREM,OSBPL3,ZNF337,DGKG,RUSC2,CNNM1,CELSR3,PLXNC1,RASGRP2,CDKL3,VPS26C,ZNF589,CAMSAP1,FOXG1,AGAP2,GAA,GABRA2,SRCAP,LILRA2,ELOVL5,SMAD1,MAP4,MYO7A,ZNF862,NCAM1,PTPA,PRKAR1B,PTCH1,ZCWPW1,EMID1,GALNT10,MRAS,FAM102A,DOCK10,SMTN,FAM214B,SLC6A8,TMCC1,STX1A,TCF7,TRPS1,LMF1" Drug 1305_DN Carcinine [56897-53-1]; Down 200; 22uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "C1QTNF3,MARK4,NCOA1,N4BP2L1,ATP6V0A1,SCAPER,CAPN3,MAP7,TPP1,NIPBL,IQCK,ARMC8,PREPL,CTH,ZNF337,MATR3,CTIF,ZNF804A,B3GAT3,DTNA,ERCC2,ANKMY1,ECSIT,TRMO,CINP,IL6R,INPP5B,SLC11A2,MAPK3,RAD51D,RGS10,CCDC25,SAFB,HSPA4L,SH3BP2,AMBRA1,DZIP1,PEX26,ARFGAP1,NXT2,PJA1,FBXW11,SYNE1,NSD1,TPD52,TPM1,SSBP2,UBE2H,NSD2,MPPE1,SMIM8" Drug 4142_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ACTN2,AP2A2,AGT,NME5,ALK,BIN1,SCAPER,CACNA1I,CFAP410,CLGN,CHN2,CHRNB2,WHRN,COL9A3,NTM,EFNB3,ELAVL2,LRRC23,CEND1,PDLIM5,GAD1,GNAL,GSTM5,SOX21,NXPH3,KLF12,KCNK2,KCNMA1,VWA5A,MYO9A,NOVA1,NOVA2,OMG,GPR85,PLTP,LRP12,CEP41,RAB3IL1,FAT4,RNASE1,ZFHX4,EMID1,SH3BP2,SMTN,SHANK2,UHRF1BP1L,KIAA1107,SEZ6L,TRPC1,SLC17A7,SSPN" Drug 6093_UP Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "KDM5D,ADORA1,LTBP4,ALK,CDC42BPA,SEMA7A,GAS7,BRINP2,ATP1A2,N4BP2L1,BAIAP3,CACNG1,CDH2,CABP1,HAPLN1,NOS1AP,SPOCK2,DCT,PLPPR4,ELAVL2,ELAVL4,DCTN2,GPM6A,GRK4,GRIK5,LSS,MAP4,MEF2C,AFDN,BCO1,NNAT,NOS1,NUMA1,TNPO2,PROX1,ELOVL2,FAT4,TRIM68,RYR1,SLC2A5,CCDC88A,SLC11A1,KDM4B,ARHGAP26,ATP10B,COLGALT2,PCDHGB6,PCDHGA10,HEY2,R3HDM1,SLC17A7" Drug 2023_UP Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "C1QTNF1,APC,ATP2B1,BCL7A,CAST,SEPT7,SRSF11,CHRM4,EPS15L1,FADS2,SPOCK2,RCAN1,EFNB3,APH1A,ING4,BSCL2,ETV1,KAT8,CAMSAP1,C1orf61,FYB1,GART,NEU3,CACFD1,TJAP1,SCAMP5,NELL2,SLC11A2,PLCB2,RETREG2,MAPK10,SPDL1,C1orf109,TTC13,PID1,RDX,PCMTD2,UEVLD,TCP11L1,ITSN1,CCDC88A,ELMO2,INTS9,ZC4H2,FCHO1,PHLDB1,PLCB1,TCF4,NPL,HIRA,XRCC4" Drug 4560_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "MRTFA,PPP4R4,CDK13,CFLAR,ST3GAL5,IL33,BTRC,SEPT7,TCEAL2,CREM,ENTPD4,HP1BP3,NR1D2,EGFR,IRAK4,ETV1,ZNF589,FGFR1,GAD1,DISC1,RND1,COPS8,NR3C1,KCNMA1,KCNN1,KIF2A,LMO2,SMAD1,TM6SF1,NF1,CNOT4,PFKFB2,LRRN3,GRAMD1C,SYTL2,PTPRN2,TMEM231,TMEM206,HKDC1,SLA,RBM26,NPAS3,MAPK8IP3,SYN2,ZEB1,GPR161,TPM2,SSBP2,WIPF1,REEP1,STMN4" Drug 2302_UP Ofloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADD2,ADORA2A,KIDINS220,SPARCL1,DOC2A,AQP4,DNAH17,ATP1A2,BACH1,CDH2,ARHGAP33,FOXN3,ARHGEF6,AKAP7,AATK,SNCAIP,DCT,MFAP3L,DNAH9,SGK2,EML1,CALCRL,VPS13B,ATP8A1,FGFR1,C1orf61,GPR153,PCLO,GRM8,HTR2A,ITIH2,KCNJ3,KCNJ5,NF1,PCSK2,PFKFB2,SERPINE2,KCTD17,SLC6A8,HECW1,ZNF423,SPTB,ARC,PCDHA5,GPR161,TNS1,TPM1,FAM155A,WIPF1,CA10,SLC17A6" Drug 2731_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADRA1D,KIDINS220,MTUS1,MRTFA,ANK3,APBB2,FAM131A,KIF1A,TAOK2,TMEM184B,AKAP7,NRG2,CREM,SUSD5,VCAN,PDE4DIP,CTNND1,USP6NL,MFAP3L,EFNB3,SORBS3,C3orf18,MTSS1L,PIPOX,F5,FHL1,AGAP2,PDLIM5,SRCAP,GPR75,GPM6B,GRM7,GRM8,JAK2,NNAT,POU6F1,FAM120C,RAB3IL1,RNASEL,ANKRD6,SLC11A1,SLC20A2,MYH15,LHPP,STX1A,SYN2,ADGRL3,ICAM5,MAP3K12,PRDM2,GDPD5" Drug 5534_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "C1QTNF3,OGT,APC,MARK4,NUMB,ALDH4A1,LRRFIP1,NCOR1,PDE4DIP,C2CD2L,CDON,MAMLD1,EFNA3,ING4,EPB41L2,DLC1,FHL1,CINP,MALT1,GRB10,DIDO1,RNFT2,HSD17B1,INPP5B,KCNJ3,KHK,LMO2,MPP2,PRPH,FAM120C,RGS3,GSTCD,ZNF821,ZNF365,SLC1A7,PPP4R3A,SCMH1,INTS9,ZCCHC24,LHPP,SEMA4A,SATB2,TRIM2,ATP13A2,SLC44A1,KCTD2,PIK3R5,PLPPR2,VGF,TFIP11,EMSY" Drug 1568_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG3,NDRG2,ADCY6,MRTFA,ARNTL,N4BP2L1,RIPK1,BACH1,BMP7,WASF1,LDLRAD4,KRIT1,ARHGAP33,RNF14,CSF1R,DCAF8,CEND1,F3,PTK2B,CAP2,EFCAB2,PDLIM5,DISC1,PRRC2B,ADAMTS13,PRDM5,ITGAM,KCNH2,KTN1,MAP4,MBD1,NUCB1,PALM,PLCD1,PRPSAP2,ZSCAN32,R3HDM2,KBTBD4,DOK5,POGZ,EHBP1,PHF24,ARHGEF12,TNS1,SEZ6L,CA14,SSBP2,HIRA,XRCC4,LMAN2L,DPF3" Drug 3928_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ABHD6,APP,CDC14B,ASPH,STX16,SYNJ2,CFAP410,USP2,CACNA2D2,QKI,CNTN1,SH2B1,RIMS2,ATN1,DTNA,FCF1,VPS13B,VPS26C,FER,FGFR1,PDLIM5,GAB1,RND1,GLS,GPD2,EML4,PCLO,ACOT7,HSF2,INPP5B,KCNN2,MAPT,ADAM22,NOS1,NUMA1,PDE3B,PLCD1,PRKAR1B,PEX5,EPN2,KDM4B,ZCCHC24,EMC1,SS18,NXT2,ST5,FAM168A,ARC,EXOC7,BEX4,PHTF2" Drug 3566_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADCY6,PLA2G6,C1QTNF3,EPB41L5,AQP4,SYNJ2,CACNB4,PLEKHB1,TAOK2,ZFYVE9,FAM149A,CSF1R,PLCH2,RIMS2,SEC14L5,ECE2,DOCK4,RIMS3,SV2A,DUSP9,EFNB3,HSD17B14,VPS13B,EFS,DISC1,MSL3,TJAP1,ITPKA,KCNB1,KCND3,KCNH2,KHK,VWA5A,LSS,BCO1,NEUROD1,PALM,ENOX1,ABLIM3,SLN,SNCA,KDM4B,TSPYL2,NFASC,TNS2,SLC44A1,R3HDM1,TRPC3,TRPM2,AMOT,CLIP2" Drug 3520_UP Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG2,ADORA1,NME5,PLA2G6,TRMT9B,KCNAB2,APBB2,CACNA2D2,TAOK2,KIAA1549L,TMEM59L,PLCH2,SDC3,SNPH,CTIF,HIPK3,ING4,REEP2,CACNG3,FGFR1,GAB1,GAP43,SRCAP,RND1,RAB30,TJAP1,MAPT,ADAM22,ZNF862,PPP2R2B,LRRN3,PRKCB,RIPOR1,RAB3IL1,GAL3ST4,KCTD17,ST6GAL1,ABLIM3,SLC2A5,PKNOX2,SLC6A9,CXXC4,PDZD2,ZCCHC24,KAZN,PCDHGA10,SYNE1,TK2,LAT2,STMN4,KCNAB1" Drug 6007_UP Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "DPF1,C1QTNF3,SRPX,LTBP4,SEMA4G,CCDC181,CFLAR,BAIAP3,CBFA2T2,RCBTB2,TCEAL2,MYRIP,NRG2,TENM4,DMPK,DTNA,VPS13B,RASGRP2,ZMYND10,ERAP1,ALDH1L1,GRK4,GSN,ELOVL5,VWA5A,NEUROD2,PURG,MAPK7,ZDHHC14,WLS,SBF1,RASA3,PPP4R3A,OGDHL,DOP1A,WDTC1,KDM4C,ATP10B,MAPK8IP3,PLCB1,SYT5,TAL1,DMXL2,PSD3,TNFRSF1B,TRPM2,UBE3A,KCNK12,DNALI1,SCG2,NUP214" Drug 6525_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "NDRG2,PLA2G6,SEMA6A,KCNAB2,DDO,AQP6,ARHGDIG,FGF17,CACNA2D1,FADS2,CNN3,CNTN1,WHRN,TENM4,GREB1,ARHGEF4,HP1BP3,ATN1,DTNA,EFNA3,ERCC2,F5,AGAP2,TPK1,NSG1,GNAO1,HLF,MAN2A2,NUMA1,NLE1,EPN1,PPP5C,RELN,RASGRF1,KCTD17,GSTCD,KCNIP1,SBF1,SH3BP2,SLC1A7,SLC9A5,NPAS3,STX1A,AJAP1,JMJD6,OBSL1,HIF3A,SLC44A1,PARD3,FLRT2,NSD2" Drug 2959_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "AMT,MARK4,SLC4A4,ADAM23,SYNJ2,CLGN,RCBTB2,CHM,FEZ1,PDE4DIP,SLITRK5,SMG7,DTNA,EGR3,EIF4G2,ERCC2,FGFR1,ATP2C1,GABRA4,SEPT9,INPP5K,MSL3,GPR19,SLC2A6,ITGA7,ITGAM,KPNA5,LSS,MAP4,SCAMP5,MX1,MYO9A,PDE4A,ENPP2,PLEC,PTPRO,RGS10,ARHGEF10L,SLC1A7,PEX26,FAM214B,ARFGAP1,PALLD,TNIK,TSPYL2,DDN,R3HDM1,KAT6B,CABIN1,TPM1,ATP6V0E2" Drug 1472_UP Levodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-04 1.00E+00 1.91E-03 2.17E-02 51 199 "ADCY2,MRTFA,CDC42BPA,APC,GAS7,ARHGDIG,ALDH4A1,ATP1A2,CDK5R1,SCAPER,HAP1,CAMK2G,CHI3L2,ASIC3,DNAJB5,WHRN,NCAN,CST3,GREB1,RUSC2,DMTN,FOXG1,FYN,INPP5K,ALDH1L1,GLYR1,GNG3,GRIK5,CACFD1,HSD17B1,INPP5B,MMP16,PENK,RETREG1,PPARA,FAM184A,EMID1,FBXO11,PPP4R3A,SMARCD3,FNBP1,KDM4C,INKA2,ARC,IQCE,SIN3B,TRIM2,WBP2,ZMYND8,KCNK12,MPPE1" Drug CID000004367 L-NNA Stitch 2.06E-04 1.00E+00 1.91E-03 2.17E-02 60 244 "ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRB2,AGT,ALDH7A1,CA4,CACNA2D1,CALM1,NGB,KYAT1,CCK,CHRM1,DMPK,EBF1,EDN1,EDN3,EDNRA,EDNRB,KCNMB2,FLT1,PDLIM5,B3GAT1,GCNT2,PPARGC1A,CRCP,GLS,KCNMB4,GRIK1,GRIN2C,GRIN2D,CIT,GUCY1A2,GUCY1B1,HBA1,TNFAIP8L3,CPT1C,HSP90AA1,IGF1,KCNMA1,KCNN1,KCNN3,NBL1,NOS1,NPY,NPPA,NPR2,OXTR,P2RY1,PDCD2,PTN,PEG10,TAC1,TAC3,TACR1,AGTPBP1,ARHGEF12,SIRT1,VIPR2" Drug CID000005083 Ro 31-8220 Stitch 2.07E-04 1.00E+00 1.92E-03 2.18E-02 75 321 "ADORA1,ADRA1B,AMPH,APAF1,DGKZ,CFLAR,CALM1,KRIT1,P2RX6,AIFM1,LRBA,AKAP12,MAML1,SNAP91,SV2B,DNM1,EDN1,EDN3,EDNRA,EDNRB,LPAR6,STX2,PTK2B,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GALR1,LPAR4,RAPGEF4,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HTR5A,JAK2,KCNMA1,P2RY13,NOS1,OPRL1,P2RX7,P2RY1,PIK3C2A,PIK3CD,PIK3R1,MBOAT7,PTPA,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,MAPK12,CCDC88A,NSFL1C,MLC1,SYT1,TACR1,TIAM1,P2RY12,PLPPR5,SLC17A7,PLD4,SLC17A6" Drug CID000004650 benzoquinone Stitch 2.08E-04 1.00E+00 1.93E-03 2.20E-02 53 209 "ACHE,APAF1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,AIFM1,CNR1,HDAC9,CHRDL1,DYNC1I1,ATN1,EN2,ENO2,COQ7,ERBB2,HSPA12B,PPP1R1B,FOXG1,IP6K2,ATP2C1,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSF2,HSP90AA1,KCNH2,ASPRV1,OGG1,PAH,PENK,ABCB1,PACSIN1,POLG,PPP5C,QDPR,GSTCD,FBXW7,ATXN7,FOXRED1,HSPA4L,SLC1A3,SNCA,SYNE1,CYB561A3,ZMAT3,TLR4,PRTFDC1,JPH3" Drug ctd:D020122 tert-Butylhydroperoxide CTD 2.12E-04 1.00E+00 1.97E-03 2.24E-02 339 1813 "ABR,ACHE,ABHD6,AS3MT,ACTN1,NDRG3,ADAR,ADD2,ADD3,ADORA1,OSBPL1A,AK2,ALAD,SRPX,AMPD3,AMPH,OGT,PKP4,APAF1,KCNAB2,APOC2,APP,LGR5,AQP4,CDK10,PDXK,CASK,ARHGDIA,CAPRIN2,ASPH,DYNLL1,ALDH4A1,ATP2A2,ATP2B1,ALDH7A1,DST,SYNJ2,ARHGEF7,FUBP1,GYG2,SGCE,C5,RAB29,CA8,DDR1,CALM1,PTBP2,CAST,CBS,RGN,AIFM1,LRBA,CDC25B,CDC27,CDC42,UBE2L6,SOCS6,CNOT8,LHX2,PLAA,CLCN3,CLU,TPP1,CLTC,CP,PREPL,C2CD2,AKAP12,NCOR2,CSF1,TENM4,ARHGEF10,SIPA1L1,VCAN,PDE4DIP,CST3,APPL1,PNPLA8,CTH,DOCK4,TCAF1,ZFYVE16,ACY3,DAPK1,DBI,HEPH,HP1BP3,CEP170,LYPD1,ZC3H11A,RABGAP1L,CHRDL1,DLG3,DMPK,DNM2,DOCK2,TOM1,DUSP9,MAMLD1,FIS1,EDIL3,TSPAN5,EDN1,SGK2,EEF1D,RBM12,SH3GLB1,SUGP2,EGFR,MBNL2,KMT5B,RASA4,EIF5,PCOLCE2,BSCL2,EML1,PLEKHO1,EPB41L2,LRRC17,ERBB2,ERBB4,EFS,RTN3,GMPR2,CD320,ECSIT,TUBA1B,EFEMP1,CHST15,SEC24B,AMOTL2,FHL1,PCYOX1,SYNCRIP,FOXM1,NELFCD,USP16,USP21,TRIM16,SARAF,ZNF234,SEPT9,SRRM4,GFAP,GFER,GFRA1,PPARGC1A,DHRS4,COPS8,RNPS1,GLDC,GLYR1,OS9,GNAS,FERMT2,PSRC1,LILRB4,PRUNE2,GPER1,NUDT21,EML4,GRIN2C,NR3C1,GSN,GSTM5,PSIP1,RNFT2,HAS2,ARHGAP19,ACOT7,HMGB1,GABARAPL2,HMGCR,HSPA1L,HSP90AA1,IFI16,IGF1,NKD1,IL6ST,INPP5B,TUBB2B,ITGA7,ITGAV,KIF5C,KTN1,STMN1,LIFR,LIMS1,LSS,SMAD1,SMAD9,MAN2A2,MAP4,MARK3,MATN2,MEST,MIA2,MITF,MOV10,MSR1,MSRA,MT1M,MTR,MX1,MYO5A,MYO7A,NACA,NAP1L1,NCAM1,NFE2L2,NFIX,SLC11A2,NTRK2,NUCB1,OGDH,PAX6,PBX1,PCDH9,OLA1,PFKP,ABCB1,SERPINE2,SERPINI1,PIK3R1,GPSM2,PLCD1,JAKMIP1,SMOX,SMIM7,ING3,TNPO2,POLR2F,PPP3CA,PPP3CC,MAPK3,MAPK8,MAPK9,NDUFS7,CYBC1,PSMA6,PTK2,SPDL1,NKAIN1,PID1,ATG16L1,RAP1GAP,RAP1GDS1,RASGRF1,RBBP8,ZDHHC4,RGS3,RGS10,NUDT11,RNH1,CCDC25,PCMTD2,RTN1,RXRA,MAPK12,SATB1,ATXN1,SCP2,HES6,SEC14L1,SCG5,ITSN1,FHOD3,R3HDM2,ANKRD6,CLSTN1,SMTN,SEPHS1,EFHD1,TET1,NAXD,SMARCC2,RCOR3,IFT122,LIMCH1,PALLD,PDZD2,KDM3A,SP2,PEG10,BEX1,SPTAN1,SPTB,SRPK2,SST,ERBIN,KANK1,GANAB,JMJD6,VAMP1,SYT1,POPDC3,EXOC7,DNMBP,FAM208A,TCEA1,TCF4,USP22,PSD3,OBSL1,PUM2,SLC35G2,SIRT1,GPR161,TIE1,TJP1,TLR4,TMPO,BEX4,PARD3,TNNT1,TP53BP1,TPM2,TRIO,TTC3,TUBB2A,CADM1,PITPNB,BCL2L13,VSNL1,NSD2,RICTOR,SF1,NDRG4,UPF3A,GDPD5,RNF103,TUBA1A,NAV3,MPPE1,PLSCR4,ST7,HNRNPA3,ACTR3B,MSRB3" Drug CID000055645 quinagolide Stitch 2.13E-04 1.00E+00 1.98E-03 2.25E-02 10 19 "DRD1,GHR,IGF1,NOVA2,PRKCB,PRKCG,SST,SSTR1,SSTR2,TRH" Drug CID005270634 library 2 Stitch 2.13E-04 1.00E+00 1.98E-03 2.25E-02 10 19 "AP2A1,AMPH,SYNJ1,CDC42,CLTC,ARHGEF6,DNM1,DNM2,DNM1L,OCRL" Drug 1212_UP "Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.17E-04 1.00E+00 2.01E-03 2.29E-02 45 170 "ABAT,ABHD6,ADRB2,ARNTL,MARK4,ST3GAL5,CHN2,SLC4A7,ABCG1,PDE4DIP,CTH,DNAJC6,C2CD2L,PLPPR4,MRNIP,RGS17,EPS8,TAOK3,BAIAP2,SORBS1,FYN,GUCY1B1,DIPK1A,MMP16,TAGLN3,PCDH9,PDGFRA,SERPINI1,RETREG1,PTCH1,RGS4,FBXW7,SH3GL3,SYBU,BTBD7,KDM4B,TNIK,ELOVL4,RGL1,SYT1,TACC1,RPGRIP1L,TGFBR3,UBE2H,DNAJC12" Drug CID000001323 DiC8 Stitch 2.18E-04 1.00E+00 2.03E-03 2.30E-02 40 146 "ABHD6,ADCY5,ADCY6,ADCY8,PLA2G6,DGKZ,DGKD,CACNA2D1,CALM1,CBFA2T2,DGKI,LRBA,CRLF1,TJP2,DGKB,DGKG,EDN1,RASGRP1,GAP43,ITGAM,KCNA6,KCND2,KCNQ2,KCNQ3,ASPRV1,NCF2,NOS1,NRGN,PDYN,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,PTHLH,TJP1,TRH,TRPC1,P2RY12,PLD4" Drug CID000061492 cobalt-60 Stitch 2.22E-04 1.00E+00 2.06E-03 2.34E-02 88 390 "METAP1D,ADCY2,ADCY5,ADCY6,ADCY8,PITPNM2,CACNA1I,CACNA1G,CA4,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,NGB,CACNA2D2,CLTC,FBXO7,CNR1,CP,PREPL,ARHGAP32,HEPH,ARNT2,DTNB,CNNM1,CACNG7,TUBD1,CACNG3,CACNG2,TUBB4A,FECH,FLT1,DNER,TUBA8,GGT7,GGT5,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3,CLASRP,HBA1,TNFAIP8L3,IGF1,TUBB2B,KCNMA1,LAMA2,MAT2A,MTR,NCAM1,NEFM,NPY,SLC11A2,PDE4A,ENPP2,PKD1,PKM,PPP3CA,PPP3CC,PRKCG,CNNM2,LAMA1,PTGR2,RYR1,RYR3,COPZ1,SLC1A2,SLC11A1,HECW1,PEG10,ADHFE1,TPCN2,CYB561A3,CABIN1,TUBB2A,TUBB1,SLC30A3,SLC30A4,PLD4" Drug 2937_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.25E-04 1.00E+00 2.09E-03 2.37E-02 47 180 "ABHD6,ADORA1,ADORA3,AMPD3,BIN1,ANK3,BCAS1,PDE8B,CDK5R2,LDLRAD4,REPS2,CHRNB2,TAOK2,CLCN4,SULT4A1,KIAA0513,RCAN1,PHC2,EFNB3,FAM13A,F3,GSN,IRAK3,VSIG4,ITPKA,LYRM9,ZNF862,NF1,NLE1,SLC25A23,CEP41,PTAFR,PLPPR1,GTDC1,SLC1A3,IZUMO4,IQSEC2,LHPP,SAMSN1,SIN3B,CHST8,THRA,TMOD1,FLRT2,VIPR2,CLIP2,ZBTB16" Drug 4694_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.25E-04 1.00E+00 2.09E-03 2.37E-02 47 180 "SERPINA3,ADORA1,ADRB2,TRMT9B,KCNAB2,PLA2G4C,PDE8B,CCDC181,LDLRAD4,USP2,GPR37L1,CRMP1,PDE4DIP,DCT,DSCAM,EDN3,SIDT2,RASGRP2,ZNF44,SIGLEC8,GPM6B,LPAR4,HLF,HPSE2,IL6R,KCNMA1,MID1,MITF,NCAM1,NELL2,CDK14,NLE1,SMIM7,PLTP,LRRN3,PTPRD,C1orf54,ATXN1,ASIC4,SLC6A9,IZUMO4,ACSBG1,SYN2,GDPD5,SEMA3B,NAV2,SSPN" Drug CID000004163 NSC186061 Stitch 2.25E-04 1.00E+00 2.09E-03 2.37E-02 34 118 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CACNA2D1,CCK,CHRM1,CRMP1,DMPK,DPYSL2,DRD1,DTNA,DMTN,CSPG5,B3GAT1,LOXL3,HRH3,HTR2A,HTR5A,MAOB,BCO1,NPY,OPRL1,SOX10,JMJD6,TAC1,TAC3,TACR1,TF,TRH,NTSR2" Drug CID000067510 bicyclo[3.1.0]hexane Stitch 2.26E-04 1.00E+00 2.09E-03 2.38E-02 8 13 "ADAR,ADARB2,MCHR1,GRM2,GRM3,KCNH2,P2RY1,TK2" Drug CID005311463 MSOPPE Stitch 2.26E-04 1.00E+00 2.09E-03 2.38E-02 8 13 "CNR1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAPK3" Drug CID000234384 alph a- Stitch 2.28E-04 1.00E+00 2.11E-03 2.40E-02 23 69 "ADRA1D,ADRA1B,ADRB2,CAPN3,CBS,CBFA2T2,PICK1,CRYBB1,DCC,LYPD1,DMD,FKTN,HSD17B1,LAMA2,MYH6,NUCB1,GSTCD,SNCB,SPTB,TTPA,TUBA1A,NELFE,NETO1" Drug CID000055582 Neuromedin L. Stitch 2.28E-04 1.00E+00 2.11E-03 2.40E-02 23 69 "ACHE,AGT,CACNA1B,CACNA1E,CCK,EDN1,EDN3,ELAVL2,TUBB4A,B3GAT1,CRCP,NR3C1,NPY,OPA1,PDYN,PENK,TMEM132D,SP2,SST,TAC1,TAC3,TACR1,HPS4" Drug CID000068733 AC1L2AC7 Stitch 2.28E-04 1.00E+00 2.11E-03 2.40E-02 23 69 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,EDN1,EDN3,CACNG7,CACNG3,CACNG2,LRRC4B,PKD1,RYR1,RYR3,TPCN2,NETO1" Drug CID011984575 2 rF2 Stitch 2.28E-04 1.00E+00 2.11E-03 2.40E-02 23 69 "ARSE,DDR1,CDC42,CHM,DLG3,DMD,TENM1,MFSD10,ERCC2,ACSL4,AFF2,IL1RAPL1,LIG4,MX1,POU3F4,RAD17,FNDC3A,SYN2,PJA1,SMG6,SYNE1,XRCC4,FTSJ1" Drug 7055_UP "Forskolin, from Coleus forskohlii; Up 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.28E-04 1.00E+00 2.11E-03 2.40E-02 48 185 "ABHD6,ADORA1,AK2,BCAS1,CFLAR,ST3GAL5,GYG2,CAMK2G,ARHGEF1,ARHGEF2,MAGI1,TPP1,WHRN,PDE4DIP,NOS1AP,ZNF589,IQCG,OGA,TRAF3IP2,AHDC1,MALT1,TDRKH,NR3C1,MAP4,PALM,PBX1,PDE3B,EPN1,PLXNB1,GON4L,RAP1GAP,ZDHHC14,SEC61A2,RPS6KA2,ATXN1,PEX26,ZBTB43,MCF2L,PSD3,CRTC1,AHCYL2,DNAJC12,WIPF1,EVI5,GDPD5,HPS4,SEMA3B,NAV2" Drug 2532_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.28E-04 1.00E+00 2.11E-03 2.40E-02 48 185 "ADORA3,C1QTNF3,BIN1,APAF1,ATP1A3,MAP7,CLCN4,CREM,RIMS2,DSCAM,PLXNC1,ING4,DMTN,TBC1D16,DLC1,KIAA1109,FHL1,CAP2,FLT1,NBEA,PDLIM5,DENND2A,GAD2,SIGLEC8,GLUL,GNG4,PTGDR2,MX1,NTRK3,P2RY1,CCSER2,RETREG1,PRKCZ,PTAFR,PTCH1,MARCH1,NUDT11,PPM1E,SLA,SLC11A1,SHANK2,SAMSN1,TMOD1,SSBP2,BEST1,ZBTB16,MAP3K12,SENP7" Drug 6965_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.28E-04 1.00E+00 2.11E-03 2.40E-02 48 185 "NDRG3,KIDINS220,AP2A2,PKP4,APP,ATP2A2,MPDZ,RAB29,CA12,CAMK2G,SCARB1,EPS15L1,COL4A5,MICAL2,GREB1,DAPK3,GIT2,EXOG,DTNA,RASGRP1,EGR3,EPB41L1,CAMSAP1,NOP56,GPR153,TJAP1,IL6ST,JAK2,IPO5,MEIS1,NCAM2,NFYA,PFKFB3,SMOX,POLG,PRKAR1B,RALGDS,BSDC1,RET,RGS3,SGK1,NUBPL,ZSWIM8,CAMTA2,SIK3,RBFOX2,TRIO,VAV1" Drug 2680_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.28E-04 1.00E+00 2.11E-03 2.40E-02 48 185 "MTUS1,APBB2,FAM131A,ATP6V0A1,HIP1R,INA,CDO1,LHX2,RAB26,PDE4DIP,DZIP3,USP6NL,DOCK4,KIAA0513,RIMS3,DNAJC6,EFNA3,MBNL2,TBC1D16,TUBB4A,TESK2,PCYOX1,NBEA,RND1,GLS,GOLGB1,PCLO,KIF3A,ITGAM,KIF5C,NCAM1,PCDH9,SERPINI1,RPS20,PALLD,ZSWIM8,SPTAN1,ELOVL4,RGL1,STXBP1,SYT11,MTCL1,CAMSAP2,TRIM2,HEY1,NPL,ZKSCAN5,SLC17A7" Drug CID002724608 "6,7-dinitroquinoxaline" Stitch 2.29E-04 1.00E+00 2.12E-03 2.41E-02 14 33 "DLG4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,MAPK7,MAPK10,MAP3K12" Drug CID000097812 decahydroisoquinoline Stitch 2.31E-04 1.00E+00 2.13E-03 2.43E-02 9 16 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRM3" Drug CID000122294 argiopine Stitch 2.31E-04 1.00E+00 2.13E-03 2.43E-02 9 16 "GRIA1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GSN,ENPP2" Drug DB00661 Verapamil Drug Bank 2.31E-04 1.00E+00 2.13E-03 2.43E-02 9 16 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNB2,CACNB4,KCNH2,KCNJ11" Drug CID006438356 Men 10627 Stitch 2.31E-04 1.00E+00 2.13E-03 2.43E-02 9 16 "BOC,TUBB4A,B3GAT1,GNAS,PTCH1,TAC1,TAC3,TACR1,VIPR2" Drug 2456_DN Ciclopirox ethanolamine [41621-49-2]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.31E-04 1.00E+00 2.13E-03 2.43E-02 49 190 "RALGAPA1,ABAT,ADRB2,AMT,APOC1,APP,C5,LDLRAD4,CAMK2G,KRIT1,TPP1,STOML1,TJP2,ARMC8,SLITRK5,CX3CR1,ELMO1,SUGP2,ST3GAL6,ALDH1L1,POLL,PSRC1,LILRA2,MAN1B1,IRF8,ITGAM,NINJ2,NRGN,NUMA1,RETREG2,PTPA,PTAFR,ZCWPW1,ERI2,HSPA4L,PPM1E,SLA,SMTN,SLC15A2,TROVE2,FCHO1,CEP68,RGL1,THBS4,METTL3,LAT2,REEP1,LAMP5,HPS4" Drug 6769_DN Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.31E-04 1.00E+00 2.13E-03 2.43E-02 49 190 "ADRA1D,ALCAM,ASPH,NCOA1,SLC4A4,BMP7,ARHGAP33,SLIT2,NMT2,RCHY1,BAG4,RCAN1,EFNA3,MBNL2,STX2,NCALD,FAM198B,FGFR1,FHL1,DISC1,ARFIP1,GLYR1,RAB30,GLS,HTATSF1,GPD2,GSN,MAP4K5,HSF2,KCNF1,MPP2,NNAT,BCAN,SHANK2,LIMCH1,ZCCHC24,SS18,VAMP1,PLCB1,ARC,ASTN2,ARHGEF12,TMOD1,TPM1,TRPC1,MICAL1,ZBTB14,MAP3K12,SMIM8" Drug 5587_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.31E-04 1.00E+00 2.13E-03 2.43E-02 49 190 "SYN3,ADD2,ADRA1D,APAF1,DDO,CCDC181,SCAPER,REPS2,CNTNAP2,ING4,ELAVL3,SPEG,KIAA1109,OLFM1,OGA,GLYR1,GLS,STON1,PCLO,SPACA9,GRIK5,GRM1,PTGDR2,LMO2,MAP2,MARK1,ADAM22,TAGLN3,MX1,LYRM9,ZNF862,NNAT,NOVA2,SERPINI1,LRP12,PTCH1,ZNF493,CARF,SCN8A,SH3GL3,SHANK2,CDK19,ATP10B,TAL1,TCF7,UBE2H,FLRT2,KCNAB1,SSPN" Drug 462_UP troglitazone; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 2.31E-04 1.00E+00 2.13E-03 2.43E-02 49 190 "SERPINA3,ABHD6,NDRG2,SYT13,AMT,APBB2,ARSF,SLC4A4,CALB2,INA,CDH18,LARGE1,CLCN3,SLC24A2,LY86,C2CD2,SH2B1,CRMP1,NCOR1,SIPA1L1,ARHGAP24,HS3ST2,DRP2,EXTL2,DLC1,DLL3,GRIK5,RASSF8,KCNJ5,MN1,NCAM1,OMG,PRRX1,GAL3ST4,RGS4,MAP6D1,PAQR6,FAM214B,PKNOX2,ARHGEF40,TMCC1,ZC3H13,TSPYL2,TRPC1,VAV1,ZNF24,SLC17A7,PLSCR4,NUP214" Drug 4707_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ASPHD1,ADORA2A,MRTFA,BIN1,CAPRIN2,ALDH4A1,CFLAR,SCAPER,BTRC,CREM,CTIF,BRINP1,RUSC2,KBTBD11,DTNA,EDNRA,MBNL2,AASS,ING4,EPB41L1,COQ7,LRRC23,ACSL4,ZNF589,FYB1,TXNL4A,MSL3,GNG4,GRB10,HSD17B1,IL6R,NF1,NFYA,PPP2R2B,ELOVL2,RAB3IL1,RGS12,RPS6KA2,ANKRD6,ZKSCAN3,SNCA,ZCCHC24,MAPK8IP3,ARC,TRIM2,ARHGEF12,CRTC1,ATP13A2,DNALI1,EVI5" Drug 4536_UP Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADCY6,ADORA2A,MRTFA,AMH,CBS,SEPT7,ADGRG1,TPP1,SH2B1,NCOR2,CSF1R,CNTNAP2,DZIP3,ARMCX2,SV2A,AK5,DMPK,SGK2,AASS,TNK2,ZNF589,FGFR3,C1orf61,AGAP2,DCTN2,SYT17,GLI2,LSS,TM6SF1,PDE4D,GRAMD1C,PROX1,PRPH,PTPRN2,RALGDS,BEND5,KLHL11,TMEM206,FAM102A,SLC15A2,SMARCA4,EMC1,ZBTB43,SYN2,KIAA1107,TBCEL,TCF4,SSBP2,OSBP2,KCNAB1" Drug 3859_DN Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "AP2A2,DOC2A,AMH,GYG2,BAIAP3,CBFA2T2,CRLF1,FOXN3,DNAJB5,RIMS2,PPP6R2,TOM1,EFNA3,MBNL2,SORBS3,EZH1,BAIAP2,INPP5K,ALDH1L1,GFER,GRIK5,MATK,ADAM22,NF1,NRGN,NTRK2,PLEC,LRP12,MINDY2,RAB3IL1,RAD52,FAM184A,ENOX1,RGS10,MAPK12,SBF1,SH3BP2,SLC1A7,SPTAN1,IQSEC2,ST5,ASTN2,KIAA1107,TCF7,R3HDM1,FAM155A,VIPR2,MICAL1,LAT2,WNK1" Drug 2468_DN Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "NDRG2,APBB2,APC,NCOA1,ARHGEF7,SCARB1,ARMC8,CTIF,RABGAP1L,CELSR3,ABI2,COQ7,KIAA1109,PDLIM5,ZMYND11,INPP5K,COPS8,HTATSF1,NCKAP1L,ATXN2L,KIF2A,MAP4,MEF2C,ZNF862,NCAM1,SERPINE2,ST8SIA5,PKN2,CNNM2,PTPRN2,RAD52,TRIM68,ARHGEF10L,SEC14L1,GALNT10,MRAS,SH3BP2,SMARCD3,SNCA,TMCC1,RAP1GAP2,TROVE2,ADGRL3,TCF4,TMPO,TRPS1,FLRT2,LAT2,NSD2,UBE3B" Drug 5636_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "KDM5D,ADD2,SPARCL1,BEGAIN,APLP1,ARHGDIG,ATP1A2,LDLRAD4,CLCN4,PICK1,CRMP1,ARHGEF4,TOX,RASSF2,DGKG,SPOCK2,C2CD2L,HIPK3,EGR3,KIAA1109,FGF13,FOXG1,PDLIM5,MYOZ2,POLL,GRIK1,HLF,VWA5A,MMP17,NOVA2,SNTG1,C19orf57,MAPK7,RGS4,ROM1,KCNIP1,SH3BP2,SLC1A7,SNCA,KDM4B,CDK19,VAMP1,SYN2,SYT5,TAL1,WSCD1,FLRT1,CLIP2,NAV2,ITM2C" Drug 2311_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "LTBP4,MRTFA,ANK3,SEMA7A,FAM131A,APOC1,CDK13,SCAPER,WASF1,RAB28,PDE4DIP,DZIP3,EDRF1,DAPK3,EGFR,SORBS3,TNK2,CGREF1,COPS8,CNTRL,GRM7,GSTM5,MAP4K5,KCNN2,VWA5A,ZNF862,NOS1,NTRK2,PALM,PC,MBOAT7,PRKAR1B,VPS13C,TMEM104,AMBRA1,FBXO11,ANKRD6,SIRT2,ZKSCAN3,EMC1,SPTAN1,EXOC7,AHCYL2,ATP13A2,TMEM121,TIAM1,TRIO,CADM1,ZBTB14,EMSY" Drug 5451_UP Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "DPF1,AP2A2,PLA2G6,ANK2,GAS7,PPP4R4,RGS20,CFLAR,LDLRAD4,CAMK2B,SLC16A4,CHRNA4,SLC4A7,LRIG1,ARHGEF4,MYEF2,MAGI2,ATN1,EGFR,AASS,ING4,STX2,FOXG1,C2orf72,MAP4,LRP1B,NF1,OMG,CEP41,MAPK7,PTHLH,RAB3IL1,RAD52,C1orf54,ZFHX4,MRAS,FAM214B,SLC6A9,CDK19,SSTR1,POPDC3,TK2,TNS1,UCHL1,FLRT2,VAV2,XRCC4,SLC30A3,WNK1,KCNAB1" Drug 4011_DN Fluticasone propionate [80474-14-2]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "APP,MARK4,ST3GAL5,BTRC,CACNB2,RAB28,SH2B1,CRMP1,AATK,VCAN,SLITRK5,ARHGAP32,TOX,SIRPA,PLPPR4,ATN1,MAMLD1,SIDT2,SORBS3,LRRC23,ETV1,FGF1,ZNF44,POLL,GPD2,TDRKH,GRM8,GUCY1A2,KIF5C,MMP16,POLG,MINDY2,PPP5C,PRPH,PTHLH,RAD51D,RGS7,RGS10,IL17RB,FBXO11,FAM214B,SLC9A5,TSPYL2,ELOVL4,SYN2,WWC1,TCF4,TK2,TRIM9,NDRG4" Drug 5385_UP Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "AP2A2,ADGRF5,MRTFA,PLA2G4C,ATP2A2,BAIAP3,NEURL1,TAOK2,ZFYVE9,DNAJB5,CNTN1,AKAP5,OSBPL3,RUSC2,ATN1,DTNA,SGK2,PDLIM5,DISC1,POLL,PCLO,RASSF8,TJAP1,KCNB1,KCNN1,LIG4,LMO2,SMAD1,MOBP,NEUROD1,SLCO1C1,PDE4B,PLCD1,MTRF1L,PPP5C,GAL3ST4,TTLL7,RPS6KA2,KCNIP1,SLC2A5,PKNOX2,DOP1A,ATP11A,WSCD1,HIF3A,TEX15,TMOD1,WIPF1,NT5M,JPH3" Drug 5472_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADORA2A,BIN1,ANK1,SEMA7A,CDK10,SEMA4G,CFLAR,RCBTB2,SULT4A1,CRYBB1,CSF1,EDRF1,JAKMIP2,SRGAP3,SGK2,EGR3,DMTN,FGF1,BAIAP2,GAD2,GFER,GLS,GNAL,TDRKH,NR3C1,SOX21,HNMT,DHX35,IGSF1,KCNJ3,LMO2,MAN2A2,CNOT4,SPATA6,PTX3,PRR5L,PAQR6,ZNF821,RASA3,SH3BP2,CCDC88A,COLGALT2,SEMA4A,TRIM2,PCDHGA10,CRTC1,ZMYND8,FLRT1,PRDM2,NAV2" Drug 2736_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "SLC4A4,CADM3,SYNJ2,CACNA1G,CACNB4,MAP7,DGKI,LARGE1,CDO1,CHI3L2,CHN2,CNN3,CNTNAP2,BRINP1,KLHL3,DRD1,DSCAM,PLXNC1,SRPK3,EPB41,ZNF549,DLC1,FHL1,EFCAB2,B4GALNT1,GCNT2,GNAL,SPACA9,GRM8,KCNN1,MAPT,MGAT3,AFDN,MYO6,NOVA2,NTRK3,PDE1C,PTPRN,RNASE1,SCN2B,SCN8A,FRMPD1,NLGN1,LIMS2,LIMCH1,ZNF415,PLCB1,TRIM2,PCDHGB6,UBE3A" Drug 6191_DN troglitazone; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "NDRG3,ADD2,AGT,FAM131A,KIF1A,BMP7,LDLRAD4,CARS,HIP1R,ENTPD6,CHRNB2,TAOK2,ZFYVE9,PLAA,OSBPL3,CTH,DTNA,ST8SIA3,ING4,EIF1,PIPOX,GAA,CRCP,POLL,MAP4,ZNF862,SLC11A2,SLC25A23,PTPA,PRKCZ,PTN,RAD51D,ZCWPW1,ZDHHC14,RGS10,PAQR6,FOXRED2,ZNF821,MRAS,SUPT20H,FUZ,PPP4R3A,MAPKBP1,ZBTB43,TSPYL2,TCF7,TMOD1,TNNT1,TRPS1,XRCC4" Drug 6157_UP Kaempferol [520-18-3]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "SPARCL1,BCAR3,APBB2,SEMA4G,LDLRAD4,CFAP410,RUNX1T1,CDH2,NMT2,DNAJB5,CREM,DGKG,E2F5,EFNB3,EGR3,ING4,ELAVL3,CDKL3,SH3YL1,TUBB4A,IQCG,GAB1,GAD2,SRCAP,TDRKH,SCIN,KCNB1,KIF5C,NRCAM,PBX1,PDE4D,LRP12,CNNM2,RAP1GAP,PRR5L,ST6GAL1,SLC2A5,PKNOX2,CXXC4,SPTAN1,TSPYL2,PHLDB1,SYT1,CAMSAP2,DMXL2,ATP13A2,TK2,LMF1,MKRN3,GAN" Drug 3835_DN Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADRA1D,APBB2,GAS7,BCAS1,ARNTL,CFLAR,SCAPER,CHM,TAOK2,ZFYVE9,CSF1,PDE4DIP,GPRASP1,DAPK3,FCF1,EIF4G1,ELN,HSD17B14,ZNF589,INPP5K,GLYR1,KITLG,ADAM22,ZNF862,NEK1,NF1,NPR2,SSH1,RETREG1,PLXNB1,MAPK8,ZSCAN2,ATG16L1,RGS10,RGS12,EMID1,SBF1,SEC14L1,SLC6A8,SMARCD3,SNCA,ZBTB43,NXT2,PLCB1,TBL1X,PSD3,TRIO,WNK1,MAP3K12,SNX27" Drug 5205_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "DPF1,AZGP1,SCAPER,BAIAP3,KRIT1,CDC42,ARHGAP33,ARHGEF6,CSF1R,MICAL2,FAM169A,SDC3,PHF14,GREB1,DOCK4,ARHGAP24,CDON,MBNL2,EGR3,HSD17B14,NRN1,FHL1,HPCAL4,GFAP,RUNDC3A,POLL,GRB10,PTGDR2,IL6ST,JAK2,MAP2,MBD1,ZNF862,SERPINE2,PTHLH,RGS12,SGK1,ASAP3,PKNOX2,SNCA,NCDN,INKA2,ATP11A,TRIM2,PCDHGA10,UCHL1,VLDLR,XRCC4,NUP214,SSPN" Drug 6417_UP CGX 0596987; Up 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ABHD6,ADCY6,MRTFA,APBB2,ARNTL,ARRB2,ADAM23,SYNJ2,BTRC,CBS,ARHGEF2,CPS1,CSNK1E,VCAN,SGSM2,SUGP2,APH1A,EPB41L2,ETV1,FGFR1,PRELID3A,GPD2,GPM6B,STON1,KLF12,DHX35,MKLN1,PDE4A,CCSER2,LRP12,PRPH,SAMD9,C1orf54,RXRA,MAPK12,SCN8A,SLC4A3,FAM214B,SIRT2,SLC22A4,IFT122,ST5,SYT1,IQCE,TBL1X,AHCYL2,TIMP4,WBP2,MAP3K12,KAT6A" Drug 1831_UP Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "KIDINS220,DGKD,ARHGAP5,ATP2B1,IL33,SOCS6,ZFYVE9,QKI,CPS1,DYNC1I1,E2F5,APH1A,ING4,AMOTL2,ARFIP1,GHR,CRCP,GLYR1,GPR17,GPR19,GUCY1B1,ARHGAP19,IFI16,IL6ST,INPP5B,JAK2,ARHGAP12,MATN3,RC3H2,CNNM2,PTCH1,RAB3A,TTLL7,KIF16B,CHD9,PEX26,ARHGAP26,SPTAN1,ELOVL4,VPS13A,COBL,KIAA0930,TRIM2,CLASP1,WBP2,HIRA,UPF3A,EMSY,EVI5,PDSS2" Drug 3458_DN Ebselen [60940-34-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ABHD6,NDRG3,KIDINS220,APBB2,BCAS1,ATM,ADAM15,MPDZ,BTRC,B4GALT6,CNOT8,QKI,SLC4A7,PDE4DIP,FAM169A,DCAF8,DBT,DNAJC6,MFAP3L,SMG7,RCAN1,TNK2,EPB41L1,ZNF589,CGREF1,GHR,DHX35,IGSF1,LIG4,MAP4,MBD1,KITLG,MMP16,RETREG1,RETREG2,PRKAR1B,APTX,ELOVL2,ZSCAN32,SIRT2,CDK19,THSD1,TACC1,SEMA4A,EXOC7,TIAM1,TMPO,BEX4,PLPPR2,MPPE1" Drug 2432_DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ABHD6,BRAP,MRTFA,CASK,MARK4,NCOA1,SCAPER,CACNA1A,RAB33A,PLAA,SH2B1,KIAA0586,RUSC2,LPAR6,TNK2,LRRC23,F5,ST3GAL6,CAMSAP1,PDLIM5,ALDH1L1,SRCAP,USP19,ZNF862,NDUFA5,NF1,CNOT4,PLCB2,PPP3CC,CNNM2,DEF8,RAB3A,RAB3IL1,ZCWPW1,ZDHHC14,SH3BP2,SMTN,CCDC88A,SLC20A2,ARFGAP1,SMARCD3,WDTC1,DDN,JMJD6,FBXW11,TCF7L2,RBFOX2,TPD52,MAP3K12,UBE3B" Drug 5430_DN Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ASIC1,SLC12A5,MRTFA,CDC42BPA,ARRB1,BMP7,MAGI1,SOCS6,TAOK2,CLCN3,CTNND2,MFAP3L,EXOG,NR1D2,DNM2,DTNA,TSPAN5,MBNL2,SEMA4D,GLYR1,RAB30,POLL,GPM6B,GPR19,CNTRL,GRIK5,MAP4K5,HNMT,IL6ST,JAK2,KITLG,MITF,MPP2,ADAM22,SETD4,PLEC,MAPK12,BTBD7,RBM34,EMC1,RPGRIP1L,SLC44A1,TK2,HIRA,KCNK12,XRCC4,SF1,SPHK2,EPM2A,SENP7" Drug 1296_DN Androsterone [53-41-8]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ACTN1,ARID1A,AP2A2,EP400,BCL7A,CAMK2G,HOMER3,CSF3R,FEZ1,CST3,ZNF337,TM9SF4,CTIF,DBN1,KIAA0753,SMG7,TRMO,LILRA2,IRAK3,JAK2,KIF2A,IPO5,MAN2A2,MEF2C,NRGN,NUCB1,PDPK1,PMS2,TNPO2,BSDC1,RGS10,MAPK12,AMBRA1,SLA,SLC6A8,SMARCC2,ZHX3,SS18,NCDN,SEPT8,NSFL1C,JMJD6,TBL1X,EHBP1,TCF4,CABIN1,UBTF,LAMP5,PRDM2,WIPF2" Drug 4117_UP Etifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ACTN2,GAS7,APOC1,RASL11B,SYNJ2,CBFA2T2,RCBTB2,CHGA,CHI3L2,LHX2,LY86,AKAP7,FAM149A,WHRN,DAPK3,SV2B,TMCC2,SNX29,PLXNC1,ELAVL3,DMTN,EPHB1,OLFM1,DCTN2,CINP,GABRA5,HLF,ICA1,KCNJ3,MIA2,MSI1,ADAM22,OMG,PCDH9,PPP5C,PRKAR1B,FAM120C,ENOX1,GSTCD,TCP11L1,SH3BP2,PPP1R9A,FAM214B,MAPKBP1,SNCA,KDM4B,KDM4C,KIAA1107,THRA,KCNAB1" Drug 3378_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADCY2,ADORA1,BEGAIN,BIN1,APAF1,APBA2,KCNAB2,APBB2,DNAH17,MTMR3,CA4,CAST,LDB2,CACNA2D2,AKAP5,CPS1,KLHL3,TRAPPC9,EFNB3,LRRC23,EFS,FHL1,GFER,GRIK5,NR3C1,HLF,TJAP1,MAP2,MEF2C,MID1,ADAM22,NOVA2,NPR2,PIK3CD,PPP5C,PRKCB,MAPK8,SAMD9,VPS13C,PTHLH,ZDHHC14,RFX2,SEMA6D,ATP10B,ROBO3,PIK3R5,TPM2,LMF1,SYNC,EPM2A" Drug 5076_DN Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "TRMT9B,KCNAB2,APC,NCOA1,BACH1,CDC42,HOMER3,CSF1R,CSNK1E,C2CD2L,PARD6A,EXOG,FAM13A,EGFR,ETV1,ZNF589,FOXG1,SEMA4D,USP21,CSPG5,GPER1,BACH2,MPP2,MX1,NF1,PDE4D,STRN3,POLG,TMEM104,ZDHHC14,GAL3ST4,RPS6KA2,MAPK12,SCN8A,ZFP30,SH3BP2,PEX26,SMARCD3,TNIK,SPTAN1,VAMP1,TK2,CADM1,UBTF,NSD2,NDRG4,SPHK2,MAP3K12,SCG2,DPF3" Drug 414_DN "estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "AGT,C1QTNF1,ALAD,ARRB2,NCOA1,ATM,SLC4A4,CAST,CBFA2T2,SYNGR3,CD38,ARHGEF2,QKI,LY86,IFFO1,CLIP3,DNM2,RCAN1,EFNA3,ING4,LRRC23,EPHB1,TUBB4A,FOLR2,GNAS,LILRA2,MAN1B1,NEK1,NELL2,NRGN,PMP22,FSD1,RALGDS,RNF220,TCP11L1,ZFP30,ASAP3,LIMS2,SNAP25,TSPYL2,FCHO1,STX1A,VAMP1,EXOC7,DMXL2,RBFOX2,VSNL1,SPHK2,PMEPA1,MAP3K12" Drug 4402_DN Tiabendazole [148-79-8]; Down 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "NME5,PLA2G4C,ASPH,MPDZ,CA4,CAMK2G,SCARB1,CDC42,ADGRG1,SOCS6,DNAJB5,SLC4A7,SIPA1L1,RIMS3,MFAP3L,DMPK,DTNA,FGF13,OGA,GAB1,SRCAP,TXNL4A,NR3C1,KPNA5,MAPT,ADAM22,CNOT4,CNNM2,ZDHHC14,GTDC1,RGS12,TCP11L1,ASAP3,WDR47,BTBD7,SLC22A4,LIMCH1,RBM34,KDM4C,ARC,DMXL2,PSD3,PCDHA6,HIRA,FLRT2,EMSY,GDPD5,ST7,KAT6A,RNF170" Drug 3454_UP Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "KDM5D,NME5,AMT,GAS7,APOC1,ALDH4A1,ATP2A2,SLC2A11,ATP6V0A1,CFLAR,GYG2,ENTPD6,ENTPD4,SH2B1,ARHGEF4,GIT2,KBTBD11,GNE,SIDT2,EFNA3,EGFR,SCARA3,PDLIM5,TPK1,GAD1,HLF,ELOVL5,TJAP1,MAP4,MPP2,NUMA1,PALM,POLG,CNNM2,RAB3A,RAD52,RALGDS,CARF,RPS6KA2,SH3BP2,FAM214B,ELMO2,WDTC1,ZHX3,CDK19,VAMP1,TCF4,OBSL1,ZKSCAN5,NT5M" Drug 6977_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ASPHD1,MRTFA,TRMT9B,BIN1,ARHGEF1,CHN2,EPS15L1,VAX2,QKI,PDE4DIP,PHF14,MED12,CNNM1,EFNA3,ELAVL3,ENO2,COQ7,ANKMY1,ZNF589,FER,ANKFY1,GPR153,GABRA2,RAB30,GPR37,INPP5B,ITPKB,KIF5C,MSI1,PDE4B,PTPRE,PAQR6,SBF1,ZNF821,SLC20A2,ZKSCAN3,RBM34,UNC5B,ELOVL4,STX1A,ARC,ASTN2,POPDC3,TMOD1,SLC30A3,EVI5,SCG2,ITM2C,EPM2A,RNF146" Drug 1630_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ARID1A,BIN1,CDC42BPA,KCNAB2,ALDH4A1,ATP6V0A1,MTMR3,GYG2,HIP1R,HOMER3,PICK1,CREM,SPOCK2,LYPD1,DMPK,ATN1,SORBS3,TENM1,ERBB2,EZH1,IQCG,RAB40B,STON1,GPER1,GRIK5,LMO2,NF1,PDPK1,GON4L,PTCH1,ZCWPW1,CLIP1,RXRA,ZNF821,SH3BP2,SMARCC2,SOX2,SPTAN1,ZBTB43,TACC1,EXOC7,TBL1X,SMG6,TRIM2,WBP2,MICAL1,VLDLR,MAP3K12,EMSY,MPPE1" Drug 6756_DN Lynestrenol [52-76-6]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ASIC1,MRTFA,ARRB2,ATM,STX16,SYNJ2,LDLRAD4,CANX,NRXN3,QKI,AKAP7,CPS1,ENTPD4,PDE4DIP,DCAF8,RUSC2,CDON,IRAK4,ETV1,ZNF589,KIAA1109,FYB1,ZNF44,GAD1,GPD2,LPAR4,EML4,IL6ST,MGAT3,MYT1,PLCD1,PLXNB1,RC3H2,MINDY2,GRAMD1C,ATG16L1,TMEM156,SFPQ,AMBRA1,PPP4R3A,ARHGAP26,SS18,KIAA1107,ZEB1,RPGRIP1L,BEX4,WIPF1,NSD2,EVI5,PHTF2" Drug 364_UP trichostatin A; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "SERPINA3,ABHD6,NDRG2,OGT,NCOA1,CADM3,SCAPER,CACNA1I,CAST,CD86,CBFA2T2,CHRM4,RAB26,FEZ1,CX3CR1,GIT2,HP1BP3,SV2B,DLG3,PLXNC1,STX2,ECSIT,FGFR1,FYN,RUNDC3A,BTN2A1,SOX21,HNMT,IFI16,MAP4,MEF2C,FXYD7,NEK1,NNAT,PDE4B,SERPINI1,GPSM2,PLEC,FOXRED2,FUZ,ZCCHC24,TSPYL2,POGZ,STX1A,TBL1X,TCF4,FLRT1,PLPPR2,SLC17A7,PCBP4" Drug 4549_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "LTBP4,FAM135A,APC,LGR5,CDK13,ATP1A3,SLC4A4,ATP2B3,BTRC,DLGAP1,PICK1,AKAP5,ENTPD4,EDRF1,BRINP1,CDON,DTNA,USH1C,NRN1,FGF1,AFF2,FYB1,GABRA2,GAD1,GLI2,GUCY1A2,HSD17B1,KCND3,LIG4,MYO7A,OPCML,OPRL1,CAMKV,LRRN3,PRKCB,BCAS3,RASGRF1,KHDRBS2,FOXRED2,FRMPD1,NLGN1,RPH3A,SLC11A1,ARHGEF9,SEZ6L,TPM1,SSBP2,VGF,SCG2,MVB12B" Drug 4318_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADD2,SLC12A5,ADORA2A,AMPD3,APC,LGR5,RASL11B,CADM3,ADAM15,SYNJ1,CHI3L2,CTIF,DTNA,EDN1,EGFR,KIAA1109,FLT1,GAB1,ZNF44,ADAM28,RND1,GLYR1,GPR17,GPER1,HLF,KITLG,NELL2,NF1,NFYA,NPTX1,NPTX2,NUMA1,PDE3B,PFKFB4,PPP5C,PTPRN2,RGS4,TMEM206,CPEB3,FNDC3A,SLC6A9,SLC11A1,SLC12A4,SNCA,ZSWIM8,TACR1,TMOD1,RBFOX2,TRPC1,LAT2" Drug 2792_DN Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ARID1A,APOC1,MARK4,BTRC,HAP1,USP2,ARHGEF2,FAM189A2,CSF1,CSF1R,CSNK1E,JAKMIP2,ZNF804A,RABGAP1L,FEM1B,FGFR1,BAIAP2,CAMSAP1,FOXG1,TPK1,SRCAP,USP19,CACFD1,RASSF8,ATXN2L,IGSF1,IL6ST,KCNH2,LMO2,MPP2,ZNF862,NUMA1,PC,PIK3CD,PRKAR1B,APTX,RAD52,BTBD7,COA1,ZCCHC24,SS18,ATP11A,EXOC7,DMXL2,NSD1,TMEM121,TK2,MICAL1,WNK1,GDPD5" Drug 3254_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "MTUS1,APC,CDC14B,ARRB1,NUMB,ATM,CFLAR,TPP1,NMT2,FADS2,QKI,COL4A5,SLC4A8,GREB1,LYPD1,SMG7,KBTBD11,DMPK,TRAPPC9,EFNA3,RBM12,EFNB3,EGFR,KAT8,FGFR1,PDLIM5,ZNF44,SEPT9,SRCAP,TXNL4A,KCNMB4,GPD2,TJAP1,IPO5,SLC25A23,CNNM2,RGS12,SLC25A36,RPS6KA2,EPN2,POGZ,SS18,DIP2A,ANKRD12,KIAA0930,PARD3,ZMYND8,WNK1,HPS4,WIPF2" Drug 4298_UP 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ADD2,CDC42BPA,PKP4,EPB41L5,CDK10,N4BP2L1,CAMK2B,RUNX1T1,TPP1,STOML1,RIPOR2,RIMS3,DLG4,DTNA,MRNIP,REEP2,ZNF44,ERAP1,GDF9,RASSF8,MARK1,MMP16,CTNNA3,NF1,NFIX,PBX1,CAMKV,MTRF1L,STRN3,PPARA,PRKAB2,MAPK8,MAPK10,PTPRD,ZSCAN2,RET,KIRREL1,FOXRED2,SH3BP2,DZIP1,SLA,SLC2A5,SPP1,MCF2L,PCDHGA10,ARHGEF12,HIF3A,TRIO,KAT6A,DPF3" Drug 3634_UP Myosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "SYN3,ADD2,ADORA1,LTBP4,MRTFA,CDC42BPA,AZGP1,CAMK2G,USP2,CBFA2T2,FOXN3,TPP1,NRG2,CNTNAP2,DBT,TMCC2,EFNB3,ELAVL3,HSD17B14,ERCC2,ANKMY1,CACNG3,PTK2B,KIAA1109,GABRG2,GAD2,CSDC2,RUNDC3A,RND1,GRM2,INPP5B,MAG,MGAT3,MN1,ADAM22,MYT1,NF1,KCNK10,PALM,MAPK8,SAMD9,SBF1,SLA,SLC11A1,WSCD1,TMEM151B,TRIO,CLIP2,SLC30A3,AP3B2" Drug 5261_UP Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ANK1,APOC1,BAIAP3,CFAP410,CACNG1,CAMK2B,RUNX1T1,GPR37L1,CLCN4,NRG2,HDAC9,NTM,DTNA,EML1,FGFR1,FHL1,FOXF2,FYN,GAB1,GAD2,HBS1L,ADAM28,ATF7,GPER1,KCNJ5,SMAD1,MSI1,TAGLN3,MX1,NTRK3,CDK18,POU3F2,ACSM5,CRTAC1,ZMAT4,MYH14,EMID1,NLGN1,SLC1A2,RPH3A,KDM4B,TSNAXIP1,ZNF423,SPART,SYT11,POPDC3,HEY2,TNS1,VAV2,LAT2" Drug 7288_UP Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "SERPINA3,SPARCL1,MRTFA,BIN1,KCNAB2,APC,APOC1,APP,SEMA4G,CFLAR,IL33,BTRC,MAP7,CRLF1,COL9A3,CREM,CRY2,CSF1,CTNND2,ARMCX2,EGFR,EIF4G2,EPHA5,ANKMY1,RRAGB,EFEMP1,TESK2,OGA,GPR75,GPR17,GPR37,KIF5C,NPPA,ODF2,ABCB1,RGS4,PAQR6,ZFP30,SLC6A8,SNCA,KDM4B,KDM4C,TROVE2,SS18,SLC35G2,TPM2,OSBP2,WIPF1,WNK1,STMN4" Drug 7492_UP semustine; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ARNTL,DNAH17,BTRC,CBS,CBFA2T2,CLU,TPP1,STOML1,SH2B1,FEM1B,DMTN,CDKL3,EZH1,ST3GAL6,FER,IQCG,TRMO,CINP,CGREF1,GAB1,GAD2,B4GALNT1,TDRKH,GRIK5,CACFD1,BTN2A1,SCIN,IL6R,KIFC3,LIG4,MDFI,NHLH1,PIK3CD,KCTD15,PMP2,CDIP1,PRPH,PTPRD,TMEM231,HSPA4L,FAM214B,SLC20A2,SNCA,WDTC1,KDM4C,HIRA,UBE2H,MAP3K12,PLSCR4,TIGD6" Drug 5109_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "MTUS1,FAM131A,ATM,BCL7A,RCBTB2,PLAA,ARMC8,CREM,SLITRK5,ARHGEF4,DBT,PARD6A,EDNRA,FEM1B,DENND4A,ETV1,CSPG5,COPS8,PRRC2B,PCLO,SLC2A6,HNMT,AGFG1,IL6ST,INPP5B,KPNA5,MAPT,SCAMP5,MITF,NFIX,STRN3,APTX,PTN,CSRNP3,LIMS2,LIMCH1,TNIK,PEG10,SYT1,ATP11A,IQCE,TCF4,ARHGEF12,TMPO,LMF1,SF1,ZBTB38,WNK1,EVI5,SNX27" Drug 3807_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "AMT,APC,SEMA4G,IL33,RAB26,WHRN,COL9A2,AKAP5,TCEAL2,NRG2,HAPLN1,CSF1,TENM4,DZIP3,KIAA0513,TBC1D5,SPOCK3,CNNM1,FAM13A,OGA,ERAP1,GPR17,EML4,ATXN2L,SHISAL1,JAK2,KIFC3,MAPT,NDP,NF1,PLXNB1,SNRK,FAT4,FAM184A,RGS7,ATXN2,RPH3A,EPN2,LIMS2,ZNF334,LIMCH1,KDM4C,ROBO3,WSCD1,TCF4,TIAM1,CBX5,TNS1,TRPC1,REEP1" Drug 1290_DN Droperidol [548-73-2]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ACTN1,ARID1A,MRTFA,CDK13,NCOA1,SH2B1,PPP1R16B,DBN1,SLC12A6,EEF1A2,SUGP2,MRNIP,BSCL2,PLEKHO1,PTK2B,KAT8,FGFR1,TRAF3IP2,STON1,LPAR4,CLASRP,VWA5A,MAP4,MAPKAP1,CDIP1,MBOAT7,TNPO2,POLG,PTPA,RAD51D,RXRA,DOCK10,AMBRA1,NUBPL,SIRT2,SLC11A1,SMARCC2,MAPKBP1,KDM4B,ZCCHC24,TSPYL2,FCHO1,CEP68,MLC1,PRRC2C,EXOC7,SYNE1,KAT6B,TNNT1,RBFOX2" Drug 5117_DN Bumetanide [28395-03-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ACTN1,ADCY6,APC,MARK4,ATM,ADGRB2,SYNJ2,FUBP1,SCARB1,REPS2,LARGE1,HAPLN1,ARHGEF10,ARHGAP32,DAPK3,SIRPA,DCTN1,ERBB2,ETV1,SEMA4D,SEPT9,MSL3,POLL,SHISAL1,MAPT,MIA2,PAK3,CDIP1,CNNM2,RIPOR1,MAP6D1,ZFP30,EPN2,SLC20A2,SMARCA4,TNIK,FNBP1,ZBTB43,TBL1X,WSCD1,TCF7L2,OBSL1,CBX5,HIRA,UBTF,VGF,EVI5,SEMA3B,SLC17A7,SNX27" Drug 3844_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ALK,MRTFA,BEGAIN,SEMA7A,PRX,MTMR3,MYRF,CALB1,HIP1R,SLC16A4,SLC24A2,NMT2,FADS2,PICK1,AKAP5,NCOR2,DAPK3,DYNC1I1,SHANK1,ATN1,ING4,ERCC2,DLC1,KIAA1109,CAMSAP1,CAMKK2,SRCAP,C1QL1,GLYR1,GPER1,GSN,HLF,ICA1,KCNJ3,LSS,NCF2,TREM2,TMOD2,PPARA,MASP1,KCTD17,SELL,ST6GAL1,RBM34,HECW1,ARC,SYT5,FLRT2,ZIC3,KAT6A" Drug 2163_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.33E-04 1.00E+00 2.13E-03 2.43E-02 50 195 "ASIC1,MTUS1,AMPD3,MARK4,ADAM23,LDLRAD4,CCNT1,CDC42,TAOK2,CNTN1,KIAA0586,CTIF,DBN1,DTNB,CNNM1,LPAR6,ING4,RASGRP2,CDKL3,F5,FLT1,OGA,ZNF44,SEPT9,POLL,KCNJ5,MX1,NF1,TREM2,PFKFB2,CCSER2,PMP22,PPARA,MAPK8,RAD52,SH3BGR,SLC11A1,SLN,DOK5,IZUMO4,EMC1,STX1A,KAZN,TCF4,TMOD1,PARD3,CABIN1,TPM1,FLRT2,KAT6A" Drug 5270_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "SPARCL1,KSR1,CACNA1I,CDO1,CNTN1,SDC3,GREB1,EFNB3,EGR3,ERCC2,FOXG1,TBR1,GABRA2,GATM,SRCAP,GRIA4,ADAMTS13,GSN,TJAP1,KCNF1,KCNK2,MAPT,MBD1,MMP17,MSI1,ADAM22,MX1,PCBP3,SERPINI1,PLTP,CEP41,PTAFR,ENOX1,RGS12,SYNDIG1,ASAP3,TNIK,NMNAT2,ARHGAP26,DMXL2,PCDHGB6,HEY2,R3HDM1,CHST5,TRPM2,WIPF1,SEMA3B,SLC17A7,KCNAB1,ITM2C,PLSCR4" Drug 6005_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "DPF1,MRTFA,ANK2,RGS20,ZSCAN18,BRINP2,NRP2,BAIAP3,USP2,DGKB,SPOCK2,JAKMIP2,MAGI2,SRGAP3,DSCAM,DYRK1A,HIPK3,EFNA3,PLXNC1,RASGRP2,HBS1L,INPP5K,SRCAP,LYVE1,GPER1,GRIK1,KLF12,IGSF1,MAP2,MID1,AFDN,MOBP,MSI1,NTRK3,MINDY2,PRODH,ELOVL2,TMEM231,KCTD17,KLHDC8A,RYR1,SH3BP2,ASAP3,FBXO11,SLC11A1,LIMCH1,FAIM2,KDM4C,GPR161,ZNF74,ST7" Drug 3425_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "APBB2,APC,APOC1,LGR5,ARHGDIG,ARRB2,MARK4,CNTFR,AKAP7,CPS1,HDAC4,DAPK3,DBN1,DRD1,DTNA,DYRK1A,EFNB3,EGFR,PLXNC1,SORBS3,ING4,ENO2,FAM198B,CAMSAP1,NSG1,GCNT2,RND1,RAB30,GNG4,TDRKH,GSN,KITLG,MMP16,ADAM22,NTRK2,SLC25A23,PTPRE,TCP11L1,CCDC88A,SHANK2,SNCA,SPART,PHLDB1,AJAP1,KAZN,SEMA4A,SYNE1,ZNF34,TK2,REEP1,PRDM2" Drug 6963_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ABHD6,ADORA2A,PLA2G6,ALK,BIN1,APLP1,DDO,CDC14B,FUBP1,CACNA2D2,DBN1,ATN1,ANKMY1,DISC1,GLYR1,POLL,PRUNE2,GRM1,AP4S1,MAP4,MAPT,MGAT3,MID1,AFDN,ADAM22,NTRK2,CCDC40,RPS6KA2,SBF1,CNKSR2,SLC1A7,LIMCH1,ZCCHC24,TSNAXIP1,EMC1,SPTAN1,TROVE2,PHLDB1,STX1A,MLC1,VPS13A,ASTN2,TACC1,TNS2,PCDHA6,PARD3,TPM1,CHST5,RUNDC3B,ST7,RNF170" Drug 1478_UP Prednisone [53-03-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADORA2A,AP2A2,SPARCL1,BEGAIN,AMPD3,BIN1,CDC42BPA,APOC1,CADM3,ADAM15,ST3GAL5,SCAPER,P2RX6,CLU,PICK1,RIMS2,EDRF1,BRINP1,RABGAP1L,MBNL2,LRRC23,ERBB4,DLC1,ZNF589,FGF1,BAIAP2,FHL1,B4GALNT1,GPD2,NR3C1,KCNQ3,MSI1,CDK18,PIK3CD,SLC25A23,PRKAR1B,MAPK8,TMEM104,PTPRD,PTPRO,RAB3A,NUDT11,SLC9A5,KIF13A,KIF21B,SSTR2,SYT11,TACC1,MCF2L,CHST8,UCHL1" Drug 4809_UP Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "CDC42BPA,PPFIA2,ARSE,MARK4,ALDH7A1,CACNB2,CRMP1,VCAN,RIMS2,CTIF,SPOCK3,DMPK,EDIL3,EDNRA,EGFR,STX2,PIPOX,CAMSAP1,DCTN2,HBS1L,PCDH17,GRM1,HRH3,ATXN2L,HLF,KCNMA1,MID1,CD200,NCAM1,NF1,NPTX1,PALM,ST8SIA5,MTRF1L,PACSIN1,MAPK7,TCP11L1,FRMPD1,SLN,KIF21B,ZNF423,SYN2,TAL1,WSCD1,ZEB1,CRTC1,PCDHA5,CLIP2,SLC30A3,WNK1,JPH3" Drug 3354_UP (-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ARID1A,NDRG2,APOC1,CDK13,N4BP2L1,CFAP410,USP2,STOML1,AKAP6,WHRN,NOS1AP,SMG7,TMCC2,EXOG,EDIL3,ERCC2,FHL1,FOXG1,PDLIM5,DLL3,RUNDC3A,IL11RA,KCNN2,MAPT,NF1,NNAT,PDE3B,PTHLH,C1orf54,RGS4,ZFHX4,TMEM206,RASA3,ASAP3,PKNOX2,CLSTN2,AJAP1,JMJD6,SYN2,SLC35G2,TF,GPR161,TLR4,HIRA,WIPF1,LAT2,SLC13A3,KCNK12,SPHK2,EMSY,PLSCR4" Drug 2722_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ACTN2,ALDH4A1,ADGRB1,CACNA1I,BTRC,RUNX1T1,SCARB1,NEURL1,CDO1,CHRNB2,STOML1,SLC4A8,CRMP1,DZIP3,BRINP1,KLHL3,EDNRA,PLXNC1,PLEKHA1,RCAN2,DMTN,RASGRP2,TUBB4A,FHL1,HPCAL4,GRIK1,HTR2A,TJAP1,ITIH2,MMP16,MPP2,ADAM22,SLCO1C1,NPPA,NPTX2,OMG,KCNK10,SPATA6,PBRM1,SLC1A2,SLC14A1,SNCA,KIF13A,DNMBP,CUX2,CRTC1,CHST8,ZNF34,TMOD1,RPRM,FLRT1" Drug 4377_UP Citalopram hydrobromide [59729-32-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "TTYH1,ADORA1,ANK1,APOC1,ARHGDIG,CHRD,ATP1A2,HIP1R,NEURL1,OSBPL3,DGKG,CTIF,BRINP1,CNIH3,MFAP3L,EDNRB,MBNL2,PLXNC1,ELAVL2,ELAVL3,ELN,TUBB4A,KIAA1109,FGF1,DLL3,RND1,GRM2,IL1RAPL1,HTR2A,IRF8,ITGA7,KCNB1,CD200,ADAM22,OMG,PENK,PIK3CD,PNMA3,RAD52,CNKSR2,SLA,ZC3H13,ARHGAP26,NFASC,SSTR1,DNAH7,HEY1,SEZ6L,LAT2,SLC30A3,SLC17A7" Drug 1534_UP Josamycin [16846-24-5]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "SLC12A5,ALK,AMPD3,AMT,APBB2,PPP4R4,PLA2G4C,MARK4,ATM,SYNJ2,BAIAP3,CFAP410,CAMK2B,ARHGEF1,ARHGAP33,TAOK2,HOMER3,HDAC4,TOX,GIT2,MFAP3L,DSCAM,STX2,ERBB4,CORO2B,FHL1,FOXG1,AGAP2,SEMA4D,GPR153,SRCAP,GRIK5,GRM8,DHX35,ICA1,IL6ST,ITIH2,ITPKB,ADAM22,ZNF862,NUMA1,CDK18,ZDHHC14,SYBU,EPN2,FAM214B,RBM34,STX1A,POPDC3,DOCK9,MPPE1" Drug 3240_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADD1,ALCAM,FAM131A,APOC1,BAIAP3,BTRC,CAMK2G,LHX2,COL4A5,COL9A2,CREM,ENTPD4,CSF1,MAML1,GIT2,DBT,LYPD1,EFNA3,MTSS1L,STX2,F8,GALC,USP19,POLL,TDRKH,STON1,EML4,ARHGAP19,ICA1,KCNQ3,MMP16,ZNF862,NF1,PLEC,RAB3IL1,COA1,WDTC1,ZCCHC24,KDM4C,UNC5B,CDK19,SPART,POGZ,ARHGEF9,PLCB1,EXOC7,PSD3,TK2,RUNDC3B,SYNC,EVI5" Drug 3758_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "SYT13,ATP2B2,SLC2A11,GYG2,CAMK2B,KYAT1,CBFA2T2,NMT2,FAM149A,WHRN,IFFO1,CHD5,ERC2,PYGO1,HS3ST2,CALCRL,EFS,CEND1,KAT8,OLFM1,FGF12,ALDH1L1,GFRA1,RUNDC3A,GNAO1,GPER1,ADAMTS13,GRIK5,ITIH2,MATK,MEF2C,KITLG,PCDH9,ENPP2,C19orf57,POU6F1,MAPK8,MASP1,PTPRO,SEMA6D,FRMPD1,SLA,PKNOX2,ARHGEF40,HECW1,SPX,TNFRSF1B,TRIO,CADM1,FLRT2,JPH3" Drug 3773_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ASPHD1,NDRG2,KLRC4,ADD1,AP2A2,NR0B1,C1QTNF3,RASL11B,CACNA1G,CAPN3,RUNX1T1,CHGB,CHN2,CHRNB2,STOML1,CREB5,DBT,CDKL3,DLC1,SEMA4D,GABRA5,GNAL,GRIN1,KCND3,LAMA2,AFDN,MMP16,NNAT,NUMA1,GPR85,MAPK10,PTAFR,RAB3IL1,MYH14,KIRREL1,STK32B,FOXRED2,CNKSR2,SLC2A5,PPP4R3A,PKNOX2,BTBD7,RIMS1,FAIM2,IZUMO4,ATP10B,PCDHA5,XRCC4,ZFP37,ZNF225,FAM13C" Drug 6470_UP Pipemidic acid [51940-44-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ABHD6,ADCY6,BEGAIN,ALDH7A1,SCAPER,CACNA1I,HAP1,CAMK2B,CLGN,ZFYVE9,QKI,CRYM,AATK,PDE4DIP,RIMS3,ATN1,EDN3,EDNRB,ELAVL3,LRRC23,FOXG1,FYN,SIGLEC8,SRCAP,GFER,GNAL,LPAR4,GRM1,HRH3,ATXN2L,HLF,PACRG,MBD1,ADAM22,NF1,LRRN3,PROX1,PTHLH,NKAIN1,NUDT11,ROM1,RPS6KA2,EMID1,KIF16B,ASAP3,PPP4R3A,TNIK,PCDHA6,PCDHA5,ZMYND8,LAT2" Drug 6617_DN Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADRA1D,NME5,BIN1,CDC42BPA,DNAH17,ALDH4A1,KYAT1,CBFA2T2,WHRN,CPS1,CREB5,KBTBD11,EXOG,MBNL2,SORBS3,MRNIP,DMTN,F3,C1orf61,DENND2A,USP19,GLRB,GLS,STON1,GPER1,GPR37,IL6ST,IL11RA,SMAD1,MAP4,MAPT,MIA2,ADAM22,NEK1,PTHLH,PID1,FAM184A,MYH14,SBF1,ZNF821,BCAN,ANKRD6,ZNF667,EMC1,SS18,ASTN2,TIAM1,NR2C2,SSBP2,EMSY,NAV3" Drug 4173_UP Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADD2,BEGAIN,APBA2,GAS7,AQP6,MARK4,N4BP2L1,CACNA1G,CDK5R2,LDLRAD4,CALB1,RUNX1T1,CDH2,CLCN4,AKAP7,MICAL2,DBT,NTM,ATN1,ELAVL3,PTK2B,TBR1,FYB1,GABRA2,GABRA5,ALDH1L1,GPER1,GRIA1,GRM8,NXPH3,IGF1,KCNMA1,KIF5A,MID1,NTRK3,KCNK10,PAX6,PPP2R2B,LRRN3,PTPRD,RASA3,CNKSR2,SLC11A1,SLC14A1,ABCC8,PCDHGB6,DOCK9,WIPF1,ZNF711,ITM2C,PARP11" Drug 4213_DN Austricine [10180-88-8]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADCY6,BRAP,APOC1,ARHGDIG,DNAH17,RIPK1,DNAJB5,IQCK,AATK,ARHGEF10,ARHGEF4,SPOCK3,ATN1,DUSP9,EGFR,PLXNC1,CDKL3,F5,ZNF589,FGFR1,CINP,OGA,DISC1,GPD2,GRM1,GRM8,KCNF1,KHK,KPNA5,PACRG,NUMA1,OGG1,ENPP2,ST8SIA5,PROX1,PTPRN2,ZSCAN2,RALGDS,ZCWPW1,GSTCD,IL17RB,SLC1A7,VAMP1,CRTC1,TIAM1,TIMP4,RIMBP2,REEP1,ZNF225,SCG2,MPPE1" Drug 2984_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ABAT,SYN3,ADCY2,NR0B1,PLA2G6,FAM135A,MRTFA,FAM131A,DNAH17,ASPH,ATP1A3,BMP7,KALRN,CLDN10,NRXN3,RAB26,RIMS2,MAGI2,EXOG,TRAPPC9,CNNM1,EFNB3,EGFR,BAIAP2,GABRA5,GAD2,GFRA1,RND1,GLRB,PCSK1N,SPACA9,GRM7,KCNC1,KHK,KIT,SMAD1,SCAMP5,ADAM22,NF1,KCNK10,FAM120C,NEK11,CXXC4,LIMCH1,SNCA,ACSBG1,TACR1,WSCD1,HIF3A,STMN4,SCG2" Drug 1443_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ARNTL,ARRB2,CAMK2G,RUNX1T1,ZFYVE9,CREM,CSF1R,OSBPL3,SLITRK5,CTNND1,STX2,CD320,TUBB4A,FCGRT,FECH,PRKAG2,MPP6,ERAP1,RAB30,MAN1B1,ELOVL5,POLR2F,PPP2R2B,MAPK10,PTK2,CCDC40,RGS12,NCBP3,NTNG1,KBTBD4,ELMO2,WDTC1,FNBP1,DBNDD2,LMO3,CLASP2,ST5,CEP68,ZFR2,SYT1,PHF24,ZMAT3,KCTD2,RBFOX2,SEZ6L,CHST5,TMPRSS5,TSC2,MPPE1,SMIM8,ACTR3B" Drug 1601_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; HL60; HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "NDRG2,AMT,CNTNAP1,APOC1,APP,CDK10,ATP2B1,BMP7,GYG2,CALB2,FOXN3,NCOR1,DBN1,ATN1,RABEPK,VPS26C,CEND1,FKTN,GPR153,GDF9,PCSK1N,GNG3,PRDM5,CLASRP,GSTM5,MAP4,ADAM22,SETD4,OCRL,PDE1C,ZFYVE21,PMS2,MBOAT7,MINDY2,SAMD9,CLIP1,BCAN,CCDC88A,SLC11A1,MAPKBP1,TSPYL2,POGZ,MAPK8IP3,TAC3,EXOC7,RBFOX2,SEZ6L,TPM3,FLRT2,VSNL1,SLC17A7" Drug 7401_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "APBB2,FAM131A,APP,CDK10,MYRF,ARHGEF2,CHM,B4GALT6,QKI,AKAP7,CSNK1E,GPRASP1,HDAC4,KIAA0513,SPATA2,SGSM2,DYNC1I1,CDON,LPAR6,EZH1,F3,BAIAP2,SRCAP,GPER1,MAN1B1,PBX1,MAPK7,SNRK,PTPN13,RAD52,RGS10,SUGCT,TMEM156,AMBRA1,PEX26,FAM214B,KDM4D,SHANK2,LIMCH1,TNIK,TTBK2,EXOC7,KIAA1107,TRIM2,PSD3,AHCYL2,CBX5,BHLHB9,EVI5,MPPE1,MARCH8" Drug 4818_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADRA1D,SRPX,APBB2,NUMB,ATM,BCL7A,SYNJ2,MTMR2,AKAP7,ARMC8,MAML1,DAPK3,GIT2,JAKMIP2,MFAP3L,RABGAP1L,TRAPPC9,EDNRA,ING4,MTSS1L,ERCC2,FHL1,DPYSL4,FAM49B,GAD1,MALT1,CNTRL,KCNH2,IPO5,ZNF862,NF1,RETREG1,TMEM104,WDR25,RAB3A,GTDC1,RPS6KA2,SBF1,TRA2B,SCAF8,EPN2,BTBD7,SNCA,THSD1,KAZN,BHLHB9,TRPC1,SPHK2,EMSY,KCNAB1,PHTF2" Drug 4626_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "TRMT9B,APOC1,APP,PDE8B,ATP2B2,CFAP410,CBFA2T2,B4GALT6,RAB28,ABCG2,RAB26,ARHGEF4,FCF1,MBNL2,VPS26C,KIAA1109,ANKFY1,EFCAB2,ZNF44,SIGLEC8,SEPT9,GART,GLRB,MSL3,GPM6B,GRIK2,CACFD1,SHISAL1,MN1,MX1,NDUFA5,NEUROD1,SETD4,CDIP1,PTPRB,SH3TC2,ATXN7,ZFP30,SLA,ZNF667,WDTC1,SOX2,TSNAXIP1,PLCB1,KAZN,TK2,TNS1,TRPC1,FAM13C,KAT6A,PHTF2" Drug 4625_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "AMT,KCNAB2,APBB2,ALDH7A1,ADGRB2,SCARB1,SYNGR3,AP4M1,TAOK2,RAB28,QKI,KIAA0513,TBC1D5,RUSC2,SGSM2,ATN1,DTNB,CELSR3,MBNL2,MRNIP,STX2,ST3GAL6,SIGLEC8,USP19,GPR17,CACFD1,DIPK1A,JAK2,KIF5C,MT1M,MX1,PAK3,PPP3CC,PRKAR1B,GON4L,ZSCAN2,FAT4,TTLL7,FOXRED2,ZNF821,FRMPD1,AMBRA1,TMCC1,RBM34,VPS13A,TMEM121,TPM2,CADM1,ZNF711,EMSY,SEMA3B" Drug 3465_DN Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "CDC42BPA,APC,FAM131A,PPFIA3,CAPRIN2,EIF4G3,ST3GAL5,CFAP410,TAOK2,SLC4A7,BAG4,CREM,MICAL2,CTH,EDRF1,TRAPPC9,HIPK3,EML1,STX2,FECH,ATP2C1,GLYR1,NR3C1,ATXN2L,HNMT,IGSF1,LIG4,GIT1,ADAM22,KCTD15,PPP5C,TMEM104,ZSCAN32,RALGDS,ATXN1,PEX26,SMARCC2,SPART,TROVE2,THSD1,FCHO1,MTCL1,SEMA4A,TIAM1,TRPC1,PLPPR2,LMF1,KLC2,KCNK12,REEP1,SEMA3B" Drug 4824_DN Letrozole [112809-51-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ARID1A,ADRA1D,PLA2G6,BIN1,APBA2,APC,FAM131A,ATM,KIF1A,BAIAP3,WHRN,SMG7,SGSM2,CDON,SUGP2,SORBS3,ENO2,MTSS1L,ERCC2,FHL1,ERAP1,SEPT9,IL6R,VWA5A,SMAD1,MAP4,SLC11A2,PDE3B,RETREG1,PPARA,PTN,FAM120C,RAB3IL1,CEP97,KCTD17,EMID1,SEC14L1,PPP1R9A,SNCA,KIF13A,RBM34,SPTAN1,ATP11A,ROBO3,SZT2,TNS2,SLC44A1,PARD3,EMSY,KCNAB1,SSPN" Drug 642_UP 6-thioguanine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "KIAA1324,ALK,AQP6,CDK10,ARNTL,RASL11B,ADAM23,AZGP1,C5,CBFA2T2,CHRM4,HINFP,RIMS2,DCAF8,ACOT8,DRP2,DSCAM,DTNA,EFNB3,SORBS3,ELAVL4,OLFM1,BAIAP2,HPCAL4,INPP5K,GPR12,GRM8,IL6ST,KCNJ5,MBD1,KITLG,AFF1,MMP17,MYT1,NUCB1,CAMKV,MBOAT7,POLG,PTPRD,RET,ATXN2,ST6GAL1,KBTBD4,SLC20A2,EXOC7,TBL1X,SZT2,NDRG4,SEMA3B,MPPE1,MVB12B" Drug 4672_DN Loperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "CDC14B,ALDH4A1,ATP1A3,ALDH7A1,MAP7,PLEKHB1,PLAA,AKAP7,SH2B1,CNTNAP2,PLXNC1,EN2,AFF2,TRMO,GABRA2,COPS8,CNTRL,HAS2,SHISAL1,JAK2,MDFI,AFF1,MN1,ADAM22,NDP,NEK1,CNOT4,PDE4B,PIK3R1,TNPO2,PPARA,PTN,ZSCAN32,ZSCAN2,TMEM231,RAB3A,BEND5,KHDRBS2,RGS10,CSRNP3,FRMPD1,TSNAXIP1,ARHGAP26,DDN,SYNE1,ARHGEF12,TMEM121,THRA,TIAM1,TK2,WNT7A" Drug 3340_DN Simvastatin [79902-63-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADORA2A,PLA2G6,MRTFA,APBB2,PLA2G4C,MARK4,CA4,CDC27,SOCS6,B4GALT6,CLU,CSF1,SDC3,EDRF1,ARMCX2,SIDT2,RBM12,ING4,STX2,FER,FGFR1,IQCG,SEMA4D,GPR153,CNTRL,SPACA9,KCNH2,KCNJ5,ADAM22,SETD4,PTN,PEX5,RAB3A,CEP97,SH3BP2,ANKRD6,ABLIM3,ZSWIM8,CDK19,ELOVL4,SEMA4A,TCF7L2,PCDHA6,TMEM121,TK2,TRPC1,VLDLR,HPS4,PCBP4,ST7,SMIM8" Drug ctd:C010792 testosterone undecanoate CTD 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "ADGRF5,AMPD3,PKP4,API5,AZGP1,PTBP2,FMNL3,CD86,DLGAP2,AHCTF1,CDC42BPB,GREB1,ZEB2,MRO,TMEM35A,IGSF6,KATNAL1,HPCAL4,NSG1,SARAF,RAPGEF6,GLYR1,ZNF638,FERMT2,LINGO1,ELOVL5,IGSF1,MBNL1,PAK3,PDE1C,TMOD2,PPP2R2C,FAM66C,KLHL11,FAM182A,CPEB3,SLC2A5,BTBD3,SNRPN,FNBP1,DOK5,SYT11,KLHL4,NACC2,DDHD1,CSMD1,RFTN2,TUBB2A,DOCK8,RTN4,HNRNPA3" Drug 6191_UP troglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "AP2A2,SEMA6A,BIN1,SLC4A4,CACNA1I,BTRC,CACNG1,CAMK2B,CH25H,CLU,CSNK1E,DAPK3,SPOCK2,TMCC2,DSCAM,SGK2,MRNIP,C3orf18,KCNMB2,CDHR1,EXTL1,F5,TUBB4A,KAT8,AGAP2,DOT1L,GAP43,ALDH1L1,PCDH17,FAM107A,KLF12,KCNJ3,MMP16,PGAM2,PLCD1,EPB41L4B,C19orf57,MINDY2,CEP41,PTPRD,PTPRN2,KCNIP1,CNKSR2,ANKRD6,PKNOX2,LIMCH1,ZC3H13,MCF2L,WSCD1,GJC2,SSPN" Drug 4176_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "TRMT9B,APC,BRINP2,ATP2B3,CACNA1G,RUNX1T1,USP2,CDH2,CHGA,CHGB,WHRN,GREB1,SPOCK3,HS3ST2,MTSS1L,ZNF391,CEND1,F5,AGAP2,FAM49B,TBR1,OGA,ARPP21,SEPT9,SOX21,GUCY1A2,KLF12,KHK,MID1,MMP17,MSR1,TAGLN3,NNAT,PDE4A,POU3F4,ELOVL2,EMID1,NTNG1,FAIM2,SOX10,IZUMO4,RBM26,MAPK8IP3,TRIM2,PCDHGB6,SYNE1,DNAH7,R3HDM1,TRPC3,SLC17A7,JPH3" Drug 6475_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "TRMT9B,AMPD3,CDC42BPA,APC,APP,CASK,LDLRAD4,B4GALT6,RAB28,ZFYVE9,FAM189A2,NRG2,C2CD2L,DLG3,CNNM1,OPTN,SORBS3,TNK2,EPB41L2,NCALD,EZH1,BAIAP2,FYB1,MALT1,PRRC2B,JAK2,MATK,NELL2,P2RY1,WDR25,PTPRE,PEX5,RGS10,RPS6KA2,WLS,FUZ,NLGN1,INTS9,LIMCH1,RBM34,SOX2,THSD1,NXT2,RPGRIP1L,PSD3,UBTF,CLDND1,KCNK12,REEP1,KCNAB1,TIGD6" Drug 268_UP genistein; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.35E-04 1.00E+00 2.13E-03 2.43E-02 51 200 "NDRG2,CBFA2T2,REPS2,CHRM4,B4GALT6,STOML1,IFFO1,SDC3,CTNND2,GIT2,FBXL5,DPYSL2,SUGP2,MBNL2,MRNIP,VPS26C,AMOTL2,SEMA4D,PNMA2,LUZP2,LILRA2,GPR19,ARHGAP19,ITPKB,ADAM22,MYL3,NRGN,OPRL1,PLEC,FSD1,MED1,RET,SAFB,SGK1,SH3BP2,FERMT1,FNDC3A,SLC9A5,KBTBD4,RCOR3,IFT122,KDM4B,FNBP1,PEG10,CLASP2,WWC1,TSC2,LMF1,ZNF23,HPS4,MPPE1" Drug CID002733635 Fm 4-64 Stitch 2.37E-04 1.00E+00 2.16E-03 2.46E-02 28 91 "SYN3,DYNLL1,BSN,CACNA1B,CALM1,RHBDL1,LRBA,CDC42,CLTC,SNAP91,CALN1,GPHN,STX2,ACTL6B,NBEA,GAD2,GPR162,TXNL4A,GRIA1,MYO5A,PTPRN2,SYBU,SHANK2,STX1A,SYN2,SYP,ACTR6,NUP214" Drug CID000037165 saxitoxin Stitch 2.41E-04 1.00E+00 2.20E-03 2.50E-02 22 65 "ASIC1,ANK2,CBLN1,ASIC3,SLC25A18,PRKAG2,NKX6-2,MYH6,MYH7,MYL3,NEUROD1,ENPP2,SCN2A,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TF,ZIC1,ST8SIA2" Drug 2446_UP Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.45E-04 1.00E+00 2.23E-03 2.54E-02 44 166 "GRAMD1B,BIN1,FAM131A,DNAH17,CFLAR,CACNA1I,HIP1R,CD86,CD38,CHN2,ZFYVE9,DNAJB5,AKAP6,COL9A3,CREM,AATK,SIPA1L1,PPP1R16B,DOCK4,CEND1,PRKAG2,GALC,NINJ2,OLR1,KCNK10,TREM2,PDE4B,PDE4D,PILRA,PRKCZ,PID1,ACSS3,ZMAT4,MAP6D1,SGK1,FAM214B,TNIK,EPB41L3,PHLDB1,ATP11A,PSD3,TPM4,TRPS1,FLRT2" Drug CID000177965 T-440 Stitch 2.47E-04 1.00E+00 2.24E-03 2.55E-02 12 26 "PDE8B,ALDH7A1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PTPRN2" Drug CID000132123 AIT-082 Stitch 2.47E-04 1.00E+00 2.24E-03 2.55E-02 12 26 "ACHE,ADORA2A,APLP1,GDA,CSF2RA,FGF1,GAD2,HTR2A,SYP,ZFP91,TNFRSF1B,EPM2A" Drug CID000132434 Ro 15-2041 Stitch 2.47E-04 1.00E+00 2.24E-03 2.55E-02 12 26 "PDE8B,ALDH7A1,NPPA,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID005221504 AC1NQH9B Stitch 2.47E-04 1.00E+00 2.24E-03 2.55E-02 12 26 "ADORA1,LGI1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4,SOX10" Drug CID000001341 AC1L1B9H Stitch 2.49E-04 1.00E+00 2.26E-03 2.57E-02 25 78 "ADCY5,ADCY6,ADCY8,ADORA2A,WASF1,CACNA2D1,LRBA,CHGB,DBT,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,ABCB1,SERPINE2,PIK3C2A,PRKACB,PRKCB,PRKCG,SLC6A1,MLC1,SCG2" Drug CID000104994 "1,N6-ethenoadenine" Stitch 2.49E-04 1.00E+00 2.26E-03 2.57E-02 25 78 "ABAT,BCHE,CACNA1A,CD38,GDA,ERCC2,POLK,GRIK4,GRIK5,ATCAY,KCNA1,KCNA2,KCNA4,KCNA6,KCNH2,OGG1,PSMA6,ATXN1,ATXN7,SLC1A3,NSD1,SMUG1,NEIL2,WRN,SLC17A7" Drug CID000003585 hemicholinium-3 Stitch 2.49E-04 1.00E+00 2.26E-03 2.57E-02 25 78 "ABAT,ACHE,AGT,KIF1A,BCHE,BSN,CHRM1,CHRNA4,CHRNB2,SLC32A1,DMPK,GAD2,BCO1,POU3F2,SLC1A2,SLC1A3,SLC6A1,SLC6A11,DDN,VPS13A,SLC44A1,TMPO,TRH,SLC17A7,SLC17A6" Drug ctd:C506614 PD 0325901 CTD 2.51E-04 1.00E+00 2.28E-03 2.60E-02 33 114 "FMNL2,NME5,ANK3,SLIT2,KIAA1549L,AKAP12,DOCK4,HDAC9,ARHGAP24,NTM,ETV1,ST3GAL6,FOXG1,IL1RAPL1,ADAMTS6,HAS2,KIT,NF1,NRCAM,PRRX1,MAPK3,RELN,PTX3,SLC6A15,TMEM156,SCG5,SPP1,STX1A,DNMBP,ZEB1,TLR4,UGT8,NAV3" Drug CID000009643 "1,2-dichlorohexafluorocyclobutane" Stitch 2.53E-04 1.00E+00 2.30E-03 2.61E-02 15 37 "CHRM1,CHRNA4,GRIA1,GRIK2,GRM1,GRM5,HTR2A,KCNH2,KCNJ3,PRKCG,PTK2,RYR1,RYR3,SCN2A,TPM3" Drug CID000100099 gamma-Glu-Gly Stitch 2.53E-04 1.00E+00 2.30E-03 2.61E-02 15 37 "GFAP,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM2,GRM3,GRM8,PDYN,GOPC" Drug CID000060803 sipatrigine Stitch 2.53E-04 1.00E+00 2.30E-03 2.61E-02 15 37 "CACNA1B,CACNA1E,CACNA2D1,ASIC3,SLC32A1,KCNK2,SCN2A,SCN4B,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SCN3B,SLC17A7,SLC17A6" Drug 423_UP staurosporine; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.55E-04 1.00E+00 2.31E-03 2.63E-02 46 176 "ACTN1,ALDH4A1,CBFA2T2,SYNGR3,CNOT8,TAOK2,CRMP1,LRIG1,DAPK3,SPOCK2,DSCAM,SIDT2,SUGP2,EPHB1,ERBB4,EXTL2,TACC2,PDLIM5,STAG2,LYVE1,GJB1,TXNL4A,ZNF638,FERMT2,ITIH2,AFF1,NAP1L1,OMG,PPM1B,MAPK8,PRODH,RAP1GAP,PAQR6,ATXN1,PALLD,KDM3A,VAMP1,EXOC7,CAMSAP2,TRIM2,OBSL1,TPM4,VAV1,SLC13A3,NAV2,MPPE1" Drug 5573_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.58E-04 1.00E+00 2.34E-03 2.67E-02 47 181 "NDRG2,OSBPL1A,BIN1,PDXK,ARHGAP5,CFLAR,CA4,HAP1,ZFYVE9,DNAJB5,ARMC8,CSF1R,CNTNAP2,EDRF1,DGKG,RCAN1,EDNRA,PTK2B,TACC2,SORBS1,GLYR1,NR3C1,GRM7,HMGCR,IL6R,IL6ST,NACA,NAP1L2,PKN2,KLK6,HSPA4L,SGK1,SH3BGR,SH3GL3,PPM1E,DOCK10,RAB3GAP1,SLN,SCN3B,DMXL2,ZEB1,TRIM2,UCHL1,VLDLR,LAT2,SF1,FXR1" Drug 966_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.61E-04 1.00E+00 2.37E-03 2.69E-02 48 186 "ASPHD1,ABHD6,AP2A2,BCAR3,PDXK,NCOA1,MPDZ,SOCS6,CHD1L,ABCG1,LRIG1,CSNK1E,ABCC5,EGR3,RGS17,STX2,FGFR3,AMOTL2,NOP56,ZNF44,GHR,GPER1,CACFD1,FICD,BRINP3,KCNJ3,KCNK1,KHK,KLC1,MAP4,SSH1,PIK3R1,RETREG1,SMIM7,STRN3,FA2H,PPP5C,RIC8B,DOP1A,VPS13A,TACC1,BEX4,ZMYND8,SSBP2,UBTF,ZNF23,TFIP11,ZNF248" Drug 4578_DN Apigenin [520-36-5]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.61E-04 1.00E+00 2.37E-03 2.69E-02 48 186 "C1QTNF1,ZBTB10,CFLAR,KRIT1,LHX2,NIPBL,RASSF2,GIT2,DBT,RHOBTB1,DLG3,EXOG,EFNA3,EGFR,LPAR6,EPHA5,ERCC2,ST3GAL6,SYNCRIP,ANKFY1,MALT1,NR3C1,IFI16,DIPK1A,SMAD1,MEIS1,MITF,PCDH9,LRP12,ING3,MINDY2,PTHLH,SEC61A2,ITSN1,DOCK10,AMBRA1,ZNF365,TTC17,ST5,RGL1,KANK1,TBL1X,TCF4,KIAA0930,CLASP1,HEY1,NDRG4,ZNF248" Drug 489_UP radicicol; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "ASIC1,C1QTNF1,LTBP4,OGT,ANK2,ASCL1,ATP6V0A1,MTMR2,SGCE,HAP1,TAOK2,PLAA,AKAP7,CREM,ENTPD4,CRYM,LRIG1,DBT,DSCAM,ELAVL4,STX2,NCALD,CAMKK2,STAU2,OGA,GABRG2,GPR37,FAM107A,RNFT2,KCNJ5,L1CAM,STMN1,MATK,NELL2,NRGN,NTRK3,PLXNB1,POLG,PSMD13,PTCH1,HSPA4L,SLC15A2,CDK5RAP2,TSPYL2,CLASP2,OBSL1,TNS1,TPD52L2,FXR1" Drug 2393_UP Prednisolone [50-24-8]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "ABR,ACTN2,ADORA3,APP,ALDH4A1,NRP2,MAP7,SLIT2,RIMS2,RIPOR2,GSDME,CDKL3,PIPOX,FOXG1,PDLIM5,KHDRBS3,INPP5K,ATXN2L,AGFG1,ICA1,JAK2,KHK,NCAM1,NPPA,PBX1,PDE3B,PLCB2,SLC25A23,MINDY2,PTAFR,RGS3,SLA,SLC11A1,SLC20A2,PALLD,WDTC1,ZSWIM8,KDM4C,SAMSN1,VAMP1,PDLIM2,CRTC1,TMOD1,PARD3,TRPS1,FLRT2,LAT2,SPHK2,ZBTB16" Drug 5567_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "PPFIA3,MARK4,CBFA2T2,SCARB1,SOCS6,TAOK2,FADS2,CRY2,SDC3,CTNND2,PHF20L1,EIF5,F3,FGFR1,MALT1,TXNL4A,RAB30,MAP4K5,ATXN2L,IL6ST,JAK2,KCNH2,KHK,VWA5A,MPP2,SMIM7,MAPK8,RALGDS,ZDHHC14,RGS3,FBXW7,WLS,SH3BP2,SHANK2,MAPKBP1,ZHX3,TROVE2,STX1A,JMJD6,WSCD1,TCF7,TCF7L2,PSD3,TMEM121,PARD3,PLPPR2,EVI5,GDPD5,ACTR3B" Drug 3377_UP Equilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "ADORA1,ARHGEF2,PLEKHB1,SLC24A2,CNTN1,TCEAL2,SDC3,ERC2,DAPK3,ARMCX2,JAKMIP2,HS3ST2,DYRK1A,EDN1,EGR3,ELAVL3,HSD17B14,ERBB2,ERCC2,REEP2,SORBS1,DISC1,GCNT2,GRM1,ITGAM,JAK2,KCNH2,MDM4,MGAT3,AFF1,MX1,NPR2,PCDHGC3,PLCB2,RET,TTLL7,SYNDIG1,SH3BP2,PKNOX2,WDTC1,MYT1L,ARHGAP26,CDK19,TAC3,VGF,VLDLR,LAT2,SEMA3B,EPM2A" Drug 2850_DN Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "SEMA6A,ALCAM,EPB41L5,ATP6V0A1,TAOK2,ARMC8,COL9A2,AKAP12,DCAF8,G3BP2,EIF5,EML1,VPS13B,LRRC23,DENND4A,ACSL4,FHL1,FOXG1,DPYSL4,GALC,TXNL4A,GLYR1,RAB30,LSS,MAP4,MPP2,GIT1,NF1,NLE1,RALGDS,ZDHHC14,RET,RGS3,WLS,ATXN2,IL17RB,SUPT20H,SGK1,FNDC3A,ZCCHC24,EMC1,SS18,ARC,WWC1,TNS2,TMPO,PLPPR2,REEP1,PHTF2" Drug 1243_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "RALGAPA1,APP,N4BP2L1,C5,IL33,WHRN,AKAP12,HAPLN1,ABCG1,VCAN,DCC,EDIL3,ING4,KCNMB2,PNMA2,INPP5K,RND1,MSL3,STON1,GPER1,BACH2,HTR2A,IGFBP1,KCNF1,KIFC3,MT1M,ZNF862,OPCML,SPATA6,MAPK7,RAD52,ROM1,DZIP1,SLC4A3,ZKSCAN3,SMARCD3,IFT122,KDM4C,MAPK8IP3,VAMP1,DNAH7,GPR161,HEY1,CABIN1,TRPC1,WIPF1,LAMP5,EMSY,PLSCR4" Drug 993_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "OSBPL1A,PLA2G6,C1QTNF3,BIN1,PPFIA3,CDC14B,RGS20,CFLAR,CAMK2G,MAGI1,TPP1,DNAJB5,CABP1,DAPK3,MFAP3L,LYPD1,EIF4G2,FOXG1,FLNC,AFF2,B4GALNT1,SRCAP,GLYR1,GLS,GNG4,GRIK5,DHX35,MSR1,NAP1L2,PIK3CD,TNPO2,MAPK8,RALGDS,RYR1,HSPA4L,SH3BGR,TSPYL2,TROVE2,MAPK8IP3,TTBK2,VPS13A,TRIM2,SZT2,TMEM151B,DICER1,TMOD1,RUNDC3B,VLDLR,FXR1" Drug 3605_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "NME5,PLA2G6,BIN1,EPB41L5,APLP1,PPP4R4,PLA2G4C,ATM,KIF1A,CFLAR,SGCE,CA4,NEURL1,PLAA,CLCN3,EDRF1,DAPK3,ACOT8,HIPK3,SUGP2,ENO2,ZNF589,FHL1,GRB10,GSN,IL6ST,ITPKB,JAK2,KCNN2,ADAM22,EPN1,MINDY2,PRKAR1B,PTN,SLC25A36,PPP4R3A,ZCCHC24,ZHX3,ARHGAP26,CLSTN2,SS18,RGL1,ATP11A,TBCEL,ZMYND8,ZKSCAN5,ZFP37,WNK1,PHTF2" Drug 5953_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "TRMT9B,BIN1,OGT,BTRC,CA4,CACNG1,SLC16A4,CBFA2T2,SCARB1,ADGRG1,RCBTB2,PLAA,CLU,QKI,SH2B1,LRIG1,EDRF1,TBC1D5,DGKG,RUSC2,RCAN1,MBNL2,SORBS3,ZNF589,SORBS1,SRCAP,ADAM28,POLL,DIDO1,NR3C1,TJAP1,MMP17,NAP1L2,NF1,NOS1,MBOAT7,SAMD9,ZSCAN32,HSPA4L,SH3BGR,POPDC3,ZEB1,PSD3,OBSL1,PCDHA5,AP4E1,UCHL1,ZFP37,SSPN" Drug 4471_DN Astemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "ASIC1,NME5,APBB1,CA12,CAMK2G,LARGE1,LHX2,KIAA1549L,NMT2,IQCK,BAG4,NRG2,CNTNAP2,SLITRK5,SDC3,ARHGAP24,DTNA,CNNM1,EML1,EPB41L1,ETV1,GAD1,KIF3A,INPP5B,KIF2A,NDP,PDE1C,POLG,PRKAR1B,MAPK8,GRAMD1C,PTCH1,ATG16L1,TTLL7,NUDT11,PAQR6,CSRNP3,ASAP3,WDTC1,COBL,KAZN,TCF4,TCF7L2,DICER1,TGFBR3,TMPO,FZD3,SMIM8,PHTF2" Drug CID000003075 NSC759576 Stitch 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "ADCY2,ADCY5,ADCY6,ADCY8,AGT,OGT,DGKD,AQP4,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CCK,ARHGEF1,CACNA2D2,BOC,SACS,EDN1,EDN3,CACNG7,CACNG3,CACNG2,PTK2B,PCYOX1,FOXM1,IQGAP2,DNER,HTR2A,IGFBP1,IL12A,KCNH2,CHST6,NEFM,NPPA,ABCB1,PIK3C2A,PKD1,RYR1,RYR3,CASC3,TPCN2,NPDC1" Drug 3966_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-04 1.00E+00 2.37E-03 2.69E-02 49 191 "LTBP4,KCNAB2,PPP4R4,CDK13,ASPH,BRINP2,BMP7,ST3GAL5,CDC42,SOCS6,CSF1,SDC3,RIMS2,DRD1,HIPK3,FEM1B,RASGRP1,EGR3,CDKL3,CEND1,EZH1,FGFR1,FAM49B,ADAMTS13,ELOVL5,HNMT,KCNF1,KCNMA1,NPTX1,PFKFB3,STRN3,MINDY2,SIDT1,RET,SELL,ZNF821,DOCK10,FAM214B,KDM4B,PLCB1,MTCL1,MCF2L,EXOC7,SZT2,ZNF34,TK2,TMOD1,NAV2,SSPN" Drug CID000440805 2-amino-5-oxohexanoate Stitch 2.66E-04 1.00E+00 2.37E-03 2.69E-02 37 133 "CALB1,CALB2,NGB,CDH2,VCAN,NCAN,SV2A,DLG4,ELAVL3,OLIG2,ADGRV1,FGF1,FGFR1,PNMA2,GFAP,GLUL,ITGAM,KCNN3,MYO7A,NEUROD1,NPY,PAX6,PRPH,RLBP1,RPE65,TNFRSF19,SLC1A3,SLC6A1,SLC6A11,SYP,CNTN2,ZFP91,RGMB,TTPA,TUB,RGMA,PCDH15" Drug CID000024587 Barium permanganate Stitch 2.66E-04 1.00E+00 2.37E-03 2.69E-02 37 133 "KCNH8,HCN2,CACNA1I,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNA2D2,CHRM1,CDON,KCNMB2,GCNT2,KCNMB4,GUCY1A2,GUCY1B1,GYG1,KCNA1,KCNH1,KCNJ3,KCNJ4,KCNJ5,KCNK3,KCNMA1,KCNN1,NPR2,P2RX7,KCNK10,PPP3CA,PPP3CC,PRKCB,PRKCG,SST,ABCC8,CABIN1,TRH,TRPC1" Drug 1566_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ACLY,NDRG3,KIDINS220,CDC42BPA,RASL11B,BCL7A,CAMK2G,P2RX6,ARHGAP33,CHRNB2,SLC24A2,FAM189A2,TMEM184B,DCAF8,SPOCK2,C2CD2L,FAM13A,APH1A,ING4,ENO2,C1orf61,EVL,POMT1,TRAF3IP2,NEU3,ALDH1L1,PCDH17,LILRB4,DIDO1,AGFG1,IFI16,MX1,MYT1,NTRK3,GPSM2,NLE1,EPB41L4B,RAD52,TRIM68,C12orf49,TMEM156,SAFB,AMBRA1,SLC6A8,CDK19,PHLDB1,TCF7L2,ARHGEF12,SPX,VPS35L" Drug 325_DN radicicol; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,ADORA2A,ANK2,DGKD,CADM3,ADAM23,MTMR2,CANX,HIP1R,FOXN3,CLCN4,CP,SEC24C,SRGAP3,DNAH9,EPB41L2,LRRC23,STX2,C1QL1,GLI2,GNAO1,MCHR1,SOX21,ICA1,KCNJ5,MEIS1,FXYD6,OPCML,CCSER2,PLCD1,FSD1,CNNM2,CCDC40,FOXRED2,SH3BP2,SH3GL3,ABLIM3,PREX2,PKNOX2,CDK5RAP2,TCF7,TNS2,SLC35G2,TF,DAAM2,TMPRSS5,AMOT,SLC13A3,UPF3A,SNX27" Drug 2315_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "PLA2G6,AMPD3,CDC42BPA,APOC1,CDK13,MARK4,ATM,SLC2A11,BMP7,SYNJ1,RAB28,ZFYVE9,QKI,SH2B1,FEZ1,SDC3,EDRF1,ATN1,RCAN1,EFNA3,EFNB3,MBNL2,ZNF589,FOXG1,EFCAB2,HBS1L,SEPT9,BTN2A1,DHX35,ITPKB,KCNN2,TM6SF1,RETREG1,PPP5C,ELOVL2,RAD52,RGS10,TCP11L1,SH3BP2,BTBD7,MAPKBP1,KIF13A,WDTC1,ZCCHC24,ST5,PLCB1,LMF1,REEP1,TFIP11,EMSY" Drug 609_DN 5666823; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,AMPD3,APBB2,PDXK,ALDH4A1,RIPK1,CFLAR,GYG2,SOCS6,CHRNB2,ARHGEF6,KLHL3,TMCC2,DRP2,MAMLD1,FAM13A,EPB41L1,FABP7,FGFR3,BAIAP2,TRMO,RASL10A,C1QL1,ZNF276,DIDO1,GRIA4,BTN2A1,NXPH3,ADAM22,NOVA1,NPPA,CAMKV,PRKAR1B,PRKCZ,QRICH1,RET,REV3L,ZFHX4,RXRG,SH3BP2,SH3GL3,SLA,ZBTB43,CLSTN2,ARHGEF12,GPR161,TNS1,TP53BP1,SEZ6L,SLC17A7" Drug 4204_DN Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,PLA2G6,TRMT9B,CDC42BPA,APOC1,KIF1A,LHX2,DNAJB5,RGS6,CNTNAP2,C2CD2L,SPOCK3,SGSM2,DNM2,ATN1,EIF4G2,MFSD10,MTSS1L,TUBB4A,ZNF589,SCARA3,FYB1,GRM1,GRM8,SOX21,KIF5C,ZNF862,PBX1,RETREG1,NLE1,FSD1,PPARA,MAPK7,PTPRB,KHDRBS2,RGS4,RGS10,SH3BP2,FRMPD1,AMBRA1,KANSL3,SOX2,VAMP1,KIAA0930,CABIN1,XRCC4,NT5M,KCNAB1,MPPE1,NUP214" Drug 4195_DN Lumicolchicine gamma [6901-14-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,PLA2G6,APC,KIF1A,SYNJ2,ARHGAP22,LHX2,DNAJB5,ARMC8,WHRN,RGS6,ATN1,MBNL2,PLXNC1,SORBS3,MTSS1L,ST3GAL6,CINP,SEPT9,GRM1,GRM8,SOX21,SHISAL1,SCIN,MAPT,MN1,NOVA1,ODF2,RETREG1,PROX1,CNNM2,ZCWPW1,KHDRBS2,RGS4,RGS10,SUGCT,SBF1,FRMPD1,KANSL3,ZNF415,SOX2,DDN,VAMP1,GPR161,TIAM1,TIMP4,TNS1,VIPR2,NT5M,KCNAB1" Drug 4802_DN Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "SLC12A5,BIN1,APBB2,APC,PDXK,PLA2G4C,NCOA1,BCL7A,MTMR3,MTMR2,ARHGAP33,ABCG1,CSNK1E,GIT2,HP1BP3,SMG7,SGSM2,ATN1,DTNA,FEM1B,CNNM1,SORBS3,TPK1,STON1,ARHGAP19,DHX35,INPP5B,LYRM9,NOS1,SERPINE2,PRKAB2,FAM120C,SH3BP2,SMARCA4,KDM4B,CAMTA2,SEMA4A,ROBO3,TCF7L2,PCDHGA10,TMEM121,CHST8,SLC44A1,THRA,TPM1,ZKSCAN5,SYNC,EVI5,GDPD5,SSPN" Drug 6101_UP Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,KIDINS220,BIN1,APC,APLP1,B3GALT2,RUNX1T1,ARHGEF10,GREB1,ARHGEF4,HS3ST2,HEYL,SRPK3,HSD17B14,IGSF6,EFS,CACNG3,ATP8A1,FHL1,GPR153,SIGLEC8,PRUNE2,LPAR4,HPSE2,MGAT3,MID1,AFDN,ZNF862,NF1,NOVA2,KCNK10,PAX6,PGAM2,RETREG1,PROX1,SAMD9,EMID1,RPH3A,PKNOX2,SLC9A5,SLC11A1,ZNF415,IZUMO4,ARHGAP26,ARC,TNS2,DAAM2,TRO,CA14,STMN4" Drug 4739_DN Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ARID1A,MRTFA,GAS7,CDC14B,ATM,MTMR3,CACNA1D,CAMK2G,ARHGAP33,ADGRG1,TAOK2,LHX2,FAM189A2,WHRN,SDC3,GREB1,DNM1,EFNB3,SORBS3,DLC1,ST3GAL6,FGFR1,CAMSAP1,FHL1,IQCG,SEMA4D,GPR153,POLL,GRM8,ATXN2L,MPP2,NF1,NPTX1,P2RY1,LRP12,SAMD9,RAB3IL1,CEP97,GTDC1,FBXW7,SH3BP2,SLC1A7,ZHX3,MAPK8IP3,STX1A,DICER1,CDK20,HIRA,PLPPR2,SSPN" Drug 2837_UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,NME5,SEMA6A,APBB2,APC,APLP1,ATM,ATP2A2,CFLAR,LDLRAD4,CACNB2,CHM,TENM4,TRAPPC9,STX2,DLC1,C1orf61,FAM49B,GAB1,GLS,INPP5B,KCNB1,AFDN,ZNF862,RETREG1,LRP12,POU3F4,PRKAR1B,MAPK10,MYH14,ZNF821,RASA3,ST6GAL1,ABLIM3,SLC1A2,KANSL3,PKNOX2,LIMCH1,KIF13A,WDTC1,ARHGAP26,VAMP1,PLCB1,DMXL2,SLC35G2,AP4E1,TRIO,TRO,ZMYND8,PRDM2" Drug 3579_UP Kaempferol [520-18-3]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ACTN2,ADORA2A,PLA2G6,SPARCL1,AMT,SYNJ2,GYG2,CACNA1D,CAMK2B,FOXN3,TPP1,DNAJB5,HOMER3,CNTN1,SNCAIP,SIPA1L1,CNNM1,EFNA3,EGR3,TUBB4A,GPR153,GAB1,GALC,IPO5,MID1,NEUROD1,NF1,PALM,PC,NLE1,PPARA,PRPH,RELN,PTHLH,CCDC40,RALGDS,RGS12,RPS6KA2,STUM,RPH3A,SLCO1A2,SPP1,JMJD6,RPGRIP1L,HEY1,PARD3,AMACR,TRPC1,SEMA3B,NAV2" Drug 2394_UP Diethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "RALGAPA1,ANK1,EPB41L5,AZGP1,RUNX1T1,NEURL1,CREM,CRMP1,NCOR1,DCAF4,DGKG,EXOG,EFNA3,LRRC23,RASGRP2,MTSS1L,PIPOX,RRAGB,FHL1,SCARA3,FOXG1,PCSK1N,ADAMTS13,ICA1,KIT,NEK1,NPY,NOVA2,NPR2,PCDH9,PDE1C,PLCD1,POU6F1,PRKAR1B,DCHS2,CNNM2,PTAFR,RASGRF1,KCNIP1,SLC20A2,WDTC1,ZHX3,SPTAN1,MAPK8IP3,ARHGEF9,IQCE,ARHGEF12,ZNF34,KCTD2,FLRT2" Drug 5111_UP Scoulerine [6451-73-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "GRAMD1B,OSBPL1A,MRTFA,TRMT9B,BIN1,CDC14B,DNAH17,KSR1,KALRN,MAP7,CBS,HOMER3,ARHGEF10,CSNK1E,PHF14,MAGI2,DTNA,CELSR3,TENM1,SPEG,APC2,NRN1,SORBS1,SPACA9,GRIK5,KLF12,SYNPO,LYRM9,PALM,PDE4D,MBOAT7,SNRK,PTHLH,ZSCAN2,RASGRF1,HSPA4L,OGDHL,ARHGAP26,ZBTB43,TROVE2,SMG6,PCDHGB6,TMOD1,CDK20,TPM3,SH3GLB2,TFIP11,WNK1,PMEPA1,NUP214" Drug 6028_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,C1QTNF3,CDC14B,ATM,CACNA1I,CA4,ARHGEF1,ARHGEF2,SEPT7,TAOK2,RCHY1,ENTPD4,CRMP1,CSF1,SIPA1L1,DCAF4,MAML1,SIDT2,ING4,ZNF589,DPYSL4,FYB1,POLL,GRM1,ELOVL5,INPP5B,KCNF1,KCNH2,MSI1,PLEC,STRN3,PRKAR1B,PRODH,RAB3IL1,CEP97,ATG16L1,SEMA6D,PPP1R9A,ZCCHC24,VAMP1,VPS13A,DICER1,TK2,PARD3,TRPC1,SSBP2,VGF,KCNK12,WNK1,KCNAB1" Drug 2851_UP Colistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ALCAM,MRTFA,CDC42BPA,APAF1,PPFIA3,ATM,CFLAR,CA12,CAMK2B,KYAT1,CTIF,DBT,SPOCK3,DMPK,SIDT2,SORBS3,GAD2,SEPT9,TXNL4A,GSN,KCNH2,KCNN2,KHK,LMO2,MAOB,MITF,NF1,GPR85,SERPINE2,SLC25A23,PPP5C,PRKAR1B,RAD52,RPS6KA2,EMID1,RYR1,PPP1R9A,ASAP3,PREX2,SLN,LIMCH1,ERC1,SMG6,TCF7,PCDHA6,TGFBR3,TRIO,ZMYND8,LMF1,MVB12B" Drug 3503_DN Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ABHD6,AP2A2,AK2,APC,APOC1,NCOA1,RIPK1,BCL7A,BTRC,CFAP410,SYNGR3,SRSF11,LRIG1,CTNND2,HDAC4,RCAN1,DTNA,SIDT2,ING4,CDKL3,VPS26C,SMC2,CACFD1,NR3C1,HNMT,ITPKB,MAP4,ADAM22,SERPINE2,PLXNB1,POLG,PRKAR1B,CNNM2,WDR25,ZCWPW1,GTDC1,GSTCD,WLS,SH3BGR,ZFP30,NUBPL,SLC20A2,UNC5B,CLASP2,SS18,PHLDB1,TCF7L2,TK2,WNK1,SSPN" Drug 7173_UP Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AMPH,PDE8B,ALDH4A1,CFLAR,SCARB1,FADS2,QKI,AKAP5,CREM,SH2B1,AKAP12,ARHGEF10,PPP6R2,DBT,HP1BP3,RCAN1,FCF1,MBNL2,EGR3,TNK2,EML1,COQ7,DMTN,ZNF44,COPS8,POLL,IL6ST,KCNJ3,LIG4,MN1,ZNF862,NAP1L2,CLDN11,PPP5C,PTAFR,PTPRE,PEX5,WLS,RASA3,SH3BP2,ASAP3,ZNF365,PPP4R3A,ZKSCAN3,PLCB1,ARC,PSD3,THRA,MAP3K12,SSPN" Drug 3178_DN Pimozide [2062-78-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AK2,TRMT9B,MARK4,CFLAR,CDK5R1,SCAPER,CAMK2G,MAGI1,ARHGEF6,ABCG1,SOCS5,CTNND2,GPRASP1,GIT2,RBM12,EML1,HSD17B14,COQ7,DMTN,VPS26C,FGFR1,ANKFY1,NUDT21,NR3C1,GRM1,LMO2,NF1,NFYA,CNOT4,CAMKV,MBOAT7,PRKACB,LRRC49,PTPRG,RGS12,RPS6KA2,SBF1,ZNF821,SLC20A2,KIF13A,WDTC1,EMC1,VAMP1,SATB2,PCDHA6,AHCYL2,THRA,REEP1,MPPE1,UBE3B" Drug 6898_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,BIN1,APBB2,SYNJ2,AP4M1,TPP1,STOML1,QKI,HOMER3,CREM,ENTPD4,PDE4DIP,EFNB3,APH1A,OLIG2,VPS26C,FHL1,B4GALNT1,DISC1,C1QL1,GLYR1,GLS,GPR19,INPP5B,NF1,PCDH9,PLCD1,PLEC,MAPK7,WDR25,PTAFR,RAD51D,RAD52,ZDHHC14,SH3BP2,FRMPD1,SLC1A7,PREX2,PEX26,ARHGAP26,IQSEC2,KAZN,MTCL1,FBXW11,CRTC1,TK2,HIRA,MICAL1,LAT2,TIGD6" Drug 1708_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,KIDINS220,PLA2G6,APP,PDE8B,MARK4,ATM,SLC2A11,ALDH7A1,SCAPER,CA4,ARHGEF1,REPS2,B4GALT6,ZFYVE9,GPRASP1,TBC1D5,LYPD1,NR1D2,EDNRA,MBNL2,PLEKHA1,DMTN,GPR153,ERAP1,SESN1,GPR19,INPP5B,JAK2,NAP1L2,NF1,NFYA,PPP2R5C,MAPK7,PTCH1,CEP97,RGS10,GSTCD,FBXO11,FNDC3A,CDK19,ARC,DMXL2,TCF7L2,TK2,TMPO,TPM1,SF1,REEP1,EPM2A" Drug 7369_UP Kawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ARID1A,ADCY6,CDC42BPA,ATP2B2,CDC42,TAOK2,STOML1,HOMER3,SDC3,USP6NL,CNIH3,SPOCK3,RABGAP1L,EIF4G2,ETV1,FGFR1,PDLIM5,ERAP1,ZNF276,SHISAL1,TJAP1,IL12A,DIPK1A,KITLG,TAGLN3,NDP,NDUFA5,CLDN11,PMP2,PPARA,WDR25,PTCH1,PTPN13,FAM120C,RAB3IL1,SH3TC2,ARHGEF10L,ROBO1,ZKSCAN3,TMCC1,CAND2,CDK19,MAPK8IP3,ASTN2,KLHL4,DOCK9,GPR161,R3HDM1,TNS1,ZKSCAN5" Drug 4965_DN Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AK2,SRPX,AMT,ARHGEF7,SCAPER,BTRC,CACNA1D,KYAT1,MAGI1,PLEKHB1,AKAP7,LRIG1,SOCS5,DZIP3,ARHGEF4,JAKMIP2,MED12,DSCAM,SORBS3,BAIAP2,C1orf61,GPR153,OGA,CRCP,CACFD1,INPP5B,KIF5C,VWA5A,MPP2,ZNF862,NPTX1,WDR25,PTHLH,RIPOR1,FAM184A,RGS10,DCUN1D2,SUPT20H,PPP1R9A,PEX26,WDTC1,ZHX3,KDM4C,WWC1,PSD3,TK2,TPM1,TRIO,VLDLR,EVI5" Drug 5322_UP Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,TRMT9B,AMH,AMPH,APBB2,APOC1,PPFIA3,ARHGDIG,C5,HAP1,TAOK2,PICK1,DSCAM,EFNA3,EGFR,MBNL2,RGS17,ANKMY1,F3,F5,DLC1,SEPT9,GLYR1,POLL,CACFD1,KCNMA1,MAP4,MPP2,MSI1,ADAM22,LYRM9,NF1,RETREG1,PACSIN1,PPP2R2B,MAPK7,RAB3A,RAD52,FAM184A,ROM1,SYBU,STX1A,EXOC7,TMOD1,CABIN1,TRPM2,VAV1,SYNC,SEMA3B,MVB12B" Drug 3766_DN Dicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,NME5,ALK,AMPD3,APBB1,GAS7,ARHGEF1,NEURL1,CDC42,PLEKHB1,B4GALT6,NRXN3,SLC4A8,CSF1,EDRF1,RIMS3,DAPK3,EDN1,ETV1,F3,PTK2B,FGF1,POLL,BACH2,HNMT,SHISAL1,ITPKA,ZNF862,PCDH9,SERPINI1,RETREG1,ZSCAN32,ACSS3,RAD52,RGS10,NEK11,TCP11L1,ZFP30,ASAP3,AMBRA1,KDM4B,POGZ,STX1A,SYT1,ATP11A,IQCE,TCF4,TNS2,TRPC1,VLDLR" Drug 4063_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ANK3,ATP2A2,KIF1A,DNAJB5,WHRN,CRMP1,ARHGEF10,DAPK3,PLPPR4,SIDT2,MBNL2,EIF4G1,SORBS3,IRAK4,LRRC23,FGFR1,FOXG1,ANKFY1,PDLIM5,GLRB,FERMT2,GRM1,SHISAL1,MAP4,MBD1,MEF2C,NPR2,OPCML,P2RY1,PDE1C,PLXNB1,WDR25,ZSCAN2,ATG16L1,RGS10,PREX2,PPP4R3A,CCDC88A,ZNF415,TROVE2,TBL1X,EHBP1,ZEB1,TRIM2,R3HDM1,UGT8,VGF,LAT2,NT5M,GAN" Drug 1821_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "KIDINS220,MTUS1,PPFIA1,PKP4,PPFIA3,CASK,ASPH,SYNJ2,CBFA2T2,CHN2,QKI,CHD1L,DZIP3,DBT,KLHL3,FCF1,SIDT2,SUGP2,EZH1,FGF1,TRAF3IP2,ARFIP1,GPR17,EML4,HNMT,HSF2,IFI16,JAK2,SH3TC2,RAP1GAP,NCBP3,SLC4A3,CCDC88A,KDM4B,ZHX3,PEG10,ARHGAP26,IQSEC2,CEP68,JMJD6,SYNE2,KAZN,TCF7L2,TRIM2,ZNF34,TMPO,TRPC1,NSD2,WNT7A,RNF146" Drug 5320_UP Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "SLC12A5,MARK4,ASPH,ALDH4A1,BTRC,HIP1R,SYNGR3,ADGRG1,TAOK2,VAX2,HOMER3,CNTNAP2,DZIP3,GREB1,RUSC2,DRD1,ATN1,DSCAM,FCF1,SORBS3,LRRC23,FHL1,NCKAP1,INPP5K,AHDC1,GFER,PSRC1,HNMT,ICA1,BRINP3,LSS,MAP4,NOVA2,NRGN,SETD4,SMOX,FSD1,PRODH,WDR25,PEX5,RPS6KA2,ITSN1,FAM102A,SHMT2,CDK5RAP2,ATP11A,MCF2L,TCF7L2,NUP214,SSPN" Drug 5486_UP Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,NME5,SEMA4G,ARRB2,ALDH7A1,CALB2,ADGRG1,RCBTB2,ZFYVE9,FADS2,AATK,CSF1,EDN1,C3orf18,RASGRP2,BAIAP2,GAD2,RUNDC3A,GNG3,GRM7,KLF12,DHX35,KCNB1,KCNJ5,MID1,NTRK2,NUMA1,ENPP2,FAM120C,FAM184A,ZNF493,ZDHHC14,SYNDIG1,KCNIP2,ZNF821,SH3GL3,EMC1,PEG10,CLSTN2,VAMP1,TK2,RUNDC3B,VAV2,VIPR2,ZNF24,SPHK2,EMSY,EVI5,MPPE1,C12orf4" Drug 2966_DN Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "GRAMD1B,APBB2,CASK,SLC4A4,EIF4G3,CAMK2G,SLC16A4,CD86,RAB28,DZIP3,DOCK4,HDAC4,RUSC2,MBNL2,EGR3,KIAA1109,FLT1,POMT1,ATP2C1,CGREF1,ERAP1,INPP5K,GLS,STON1,ITGAM,MAP4,MX1,OLR1,PDE4D,SMIM7,PPP3CC,PKN2,PTK2,FAM192A,SBF1,SGK1,FBXO11,SLC20A2,TNIK,SP2,ARHGAP26,KIF1B,MAPK8IP3,DNMBP,TCF7L2,AHCYL2,AP4E1,RBFOX2,TRPS1,ZNF32" Drug 4312_UP Benfotiamine [22457-89-2]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ACHE,ADD2,SLC12A5,MARK4,KIF1A,CACNA1I,CACNA1G,CACNB2,NEURL1,ADGRG1,IFFO1,CYBB,MFAP3L,HS3ST2,ATN1,DMTN,EYA1,DLC1,OLFM1,DPYSL4,SEPT9,GRM8,KCND3,KCNMA1,LSAMP,NPR2,NPTX1,PALM,CDK18,PDE3B,RETREG1,EPN1,PURG,PROX1,SYNDIG1,SEMA6D,SCN3A,CPEB3,ZNF334,HECW1,IQSEC2,SYT5,ATP11A,MCF2L,TAL1,KLHL4,AMACR,VGF,XRCC4,NDRG4" Drug 3132_UP THIP Hydrochloride; Up 200; 22.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ABAT,C1QTNF3,ANK3,APBA2,PLA2G4C,MPDZ,FUBP1,GYG2,CHRM4,CHRNA4,CNTN1,NCAN,DLG3,E2F5,SORBS3,FOXG1,GABRA1,GABRA4,SRCAP,PCDH17,ATF7,GPR22,AP4S1,HRH3,SCRG1,HTR2A,MOBP,ADAM22,NRCAM,OMG,LRP12,MAGEL2,MBOAT7,BCAS3,PTCH1,ACSS3,TTLL7,ROM1,NEK11,SYNDIG1,FOXRED2,ZNF667,SNCA,EMC1,SPART,TCF4,ARHGEF12,THRA,UBE3A,MAP3K12" Drug 4238_DN Seneciphylline [480-81-9]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,PLA2G6,APC,APOC1,CDK10,SLC4A4,KIF1A,TAOK2,LHX2,WHRN,ARHGEF10,SDC3,ARHGAP24,SMG7,ATN1,SORBS3,PLEKHO1,LRRC23,ST3GAL6,FGFR1,OGA,FYN,GABRA2,RUNDC3A,LPAR4,KCNN1,MAPT,AFF1,OGG1,PALM,PBX1,PDE4B,PLXNB1,PPARA,PRKAR1B,WDR25,ZSCAN32,RGS4,RGS7,FRMPD1,PEX26,DOK5,TRIM2,TRIO,AMACR,OSBP2,VAV2,XRCC4,KCNAB1,TIGD6" Drug 2225_DN Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,ABHD6,AMPD3,CFLAR,SYNJ2,GYG2,SCARB1,HOMER3,PICK1,SLC4A8,HDAC4,ARMCX2,MFAP3L,SMG7,DMPK,DSCAM,SORBS3,FER,TXNL4A,GLYR1,GLS,POLL,PRRC2B,GPR19,DHX35,ITPKB,MMP16,NPR2,NUMA1,PIK3CD,NLE1,SLC25A23,PTHLH,ZSCAN32,ZSCAN2,TCP11L1,FNDC3A,SYBU,ZNF365,SLC22A4,CDK5RAP2,ZCCHC24,THSD1,SEPT8,STX1A,ROBO3,TNS2,TMOD1,VAV2,ZIC3" Drug 5759_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,ADRA1D,AP2A2,NME5,APOC1,CDC14B,ARNTL,STX16,BTRC,CA8,B4GALT6,CREB5,VCAN,SDC3,ARHGEF4,TOX,RASSF2,MFAP3L,IRAK4,COQ7,EZH1,FGF13,GAD1,INPP5K,GNG4,PCLO,HAS2,NDP,PBX1,PLCD1,GRAMD1C,TMEM231,RAB3A,FBXW7,FBXO11,DOK5,ARHGAP26,THSD1,SEPT8,COBL,KAZN,KIAA0930,GPR161,LMF1,WIPF1,LAT2,XRCC4,TFIP11,MAP3K12,HPS4" Drug 5824_UP Meropenem [96036-03-2]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "C1QTNF1,SEMA7A,SEMA4G,ATP2B3,CFLAR,CACNA1I,CACNA1D,CAMK2B,ARHGEF2,FOXN3,CNOT8,QKI,PHF14,ARHGAP24,RIMS3,CTIF,TRMO,GRM1,KCND3,KCNJ5,KIF5C,KIFC3,MAP2,MOBP,TAGLN3,NPY,CDK18,PENK,RC3H2,BCAS3,SNRK,PTPRE,MYH14,GSTCD,KIRREL1,NEK11,UEVLD,FBXW7,TCP11L1,FAM192A,SBF1,FNDC3A,WDTC1,TSNAXIP1,CEP68,KIAA1107,CADM1,VAV2,WIPF1,RNF146" Drug 4689_DN Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADORA2A,DOC2A,BIN1,ANK3,APBA2,MARK4,BMP7,CA4,B4GALT6,CLCN3,VAX2,ARMC8,BRINP1,JAKMIP2,DRD1,ATN1,RCAN1,MBNL2,AASS,ACSL4,ST3GAL6,BAIAP2,FHL1,SEMA4D,PDLIM5,FAM49B,SEPT9,GFER,GNG4,GRM8,HSF2,IPO5,ADAM22,NEUROD1,NF1,PIK3R1,SLC25A23,SAMD9,PTN,RAB3A,MAPK12,SOX2,MAPK8IP3,VPS13A,AHCYL2,THRA,TMOD1,SPHK2,DNALI1,KAT6A" Drug 7470_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "SLC12A5,PLA2G6,MRTFA,ALDH4A1,NRP2,CFLAR,BMP7,C5,CACNA1A,CACNG1,CBFA2T2,AP4M1,ADGRG1,CHM,CREM,CSF1,RABGAP1L,MRNIP,VPS13B,FAM198B,GAB1,USP19,GLYR1,BTN2A1,RNFT2,ACOT7,MAP4,MIA2,MPP2,ZNF862,NF1,NOS1,NOVA1,MAPK8,WDR25,RIPOR1,MYH14,WLS,ANKRD6,SLC1A7,FAM214B,SLC6A9,SMARCD3,KDM4C,MCF2L,EXOC7,SMG6,TK2,ZBTB14,NAV2" Drug 2952_DN Betulin [473-98-3]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "BRAP,GRAMD1B,AMT,APAF1,CDK10,SLC4A4,C5,CAPN3,CBFA2T2,SOCS6,IQCK,CREM,SIPA1L1,PDE4DIP,CST3,CTNND1,DOCK4,RUSC2,TSPAN5,FAM13A,EIF1,ENO2,NCALD,PIPOX,LILRA2,GSN,SCAMP5,MX1,NPR2,SLC11A2,OLR1,PFKFB4,PIK3R1,PTAFR,RAD52,RGS3,MAP6D1,ZNF821,ITSN1,DZIP1,ANKRD6,SLC1A7,DDN,DNMBP,TCF4,TPM3,EVI5,GDPD5,PRDM10,PLSCR4" Drug 7276_UP Disopyramide [3737-09-5]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "APC,SLC4A4,EIF4G3,CFLAR,NRXN3,ZFYVE9,PLAA,ENTPD4,HDAC9,GIT2,CNIH3,SMG7,DRP2,EFNA3,AASS,EN2,PLEKHO1,LRRC23,ATP8A1,KIAA1109,NCKAP1,HTATSF1,GRM8,KLF12,IFI16,INPP5B,KIF2A,KIF5C,LRP12,PPARA,PRKAB2,RAB3A,RGS10,TTLL7,CLIP1,TRAPPC13,TMCC1,CAND2,DIP2A,SMG6,TRIM2,THRA,R3HDM1,HIRA,WNT7A,SH3GLB2,UPF3A,KAT6A,PHTF2,RNF146" Drug 6777_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,ALAD,CDC42BPA,ARRB1,PLA2G4C,ASPH,CAMK2G,B4GALT6,SLIT2,TPP1,CRY2,FEZ1,ARHGEF10,CTH,DNM1,PLEKHO1,FGFR3,FOXG1,FAM49B,CSPG5,ERAP1,DISC1,SRCAP,CNTRL,BTN2A1,INPP5B,MATK,NEK1,NFYA,CNOT4,PDE3B,SMIM7,STRN3,FSD1,RAD51D,FAM184A,GSTCD,FOXRED2,ABLIM3,WDTC1,SOX3,SPATA7,TSPYL2,NXT2,KLHL7,ARC,PARD3,CDK20,UPF3A,SMIM8" Drug 3025_UP Acetaminophen [103-90-2]; Up 200; 26.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADCY6,SPARCL1,ANK2,ASCL1,CADM3,CACNA1G,CACNB4,THSD7A,ARHGAP33,CHGA,CHN2,NRXN3,FAM149A,WHRN,COL9A3,NOS1AP,ATN1,HEYL,AASS,SRPK3,EPB41,CORO2B,DENND2A,GAP43,SIGLEC8,ALDH1L1,RUNDC3A,GPR37,HPSE2,HNMT,KCNMA1,MATN2,NPY,NTRK3,SEPT4,PPP1R1A,PTPRN2,RGS4,MAP6D1,PALLD,ATP10B,ARC,SYT1,PHF24,ATP13A2,TRIO,TRO,WNT7A,KCNK12,PRDM2" Drug 3545_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,C1QTNF1,ATP2B2,CADM3,SYNJ2,SCAPER,MTMR7,CHGA,TPP1,TMEM59L,COL9A3,VCAN,RIMS3,DTNB,PLXNC1,HSD17B14,RASGRP2,DLC1,CAMSAP1,FLNC,FYB1,SEPT9,TOX3,GPM6A,STMN2,GRM3,KCND3,LAMA2,SMAD1,ADAM22,NF1,NTRK3,DUSP26,SEPT4,ELOVL2,PTN,PTPRB,FAM120C,RGS4,RGS12,FRMPD1,ABLIM3,SLC1A7,SNCA,ATP10B,WSCD1,PRDM2,SEMA3B,NLRP3,JPH3" Drug 3085_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,GRAMD1B,AP1B1,MTUS1,BIN1,APC,ARNTL,ASPH,CBR1,NIPBL,BAG4,CSF3R,VCAN,ZNF337,SPATA2,SMG7,DTNA,STX2,TESK2,KIAA1109,CAMKK2,CELF1,TRAF3IP2,ERAP1,DISC1,LPAR4,PCLO,AGBL5,KPNA5,VWA5A,MAP4,NDUFA5,NFYA,NRCAM,NRGN,NUCB1,OPA1,PTPA,PPP3CC,RPS6KA2,RXRA,AMBRA1,ARFGAP1,CDK19,CABIN1,HIRA,NPDC1,UBE3B,PHTF2,NLRP3" Drug 2430_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "DOC2A,CNTNAP1,APBA2,ALDH4A1,CDK5R1,AP4M1,STOML1,SULT4A1,CREM,CSF1,CNTNAP2,RIMS2,EDRF1,DCT,SORBS3,EPHB1,CEND1,FGF1,PRELID3A,GAB1,ERAP1,GCNT2,GPM6B,PCLO,GRIN1,GSN,AP4S1,GUCY1A2,NCKAP1L,KCNJ5,KCNMA1,MAP4,MAPT,MOBP,PDE4D,PLP1,BEND5,KHDRBS2,SEC61A2,SH3BGR,FAIM2,WDTC1,ZC3H13,DDN,PHLDB1,MCF2L,RUNDC3B,UBTF,SH3GLB2,ACTR3B" Drug 2198_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,BRAP,APAF1,ATP6V0A1,ADAM23,MPDZ,SGCE,USP2,SEPT7,ZFYVE9,DGKG,HIPK3,SIDT2,RASGRP2,CAMSAP1,PRRC2B,GPR19,GPR22,GRIK5,PADI2,IL6ST,MDM4,MEF2C,MOBP,MPP2,NUMA1,SETD4,CEP41,RAB3A,RGS10,ARHGEF10L,TCP11L1,SYNDIG1,SBF1,ITSN1,LIMS2,SLC11A1,ZNF667,SNCA,KDM4B,DOP1A,IZUMO4,CAMSAP2,WWC1,TCF7,PSD3,FLRT2,VSNL1,ZNF32,MKRN3" Drug 6627_DN Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,NME5,CDC42BPA,APOC1,APP,SEMA4G,CDK13,KSR1,ST3GAL5,MYRF,BTRC,CBFA2T2,SCARB1,LARGE1,CLCN4,STOML1,RAB26,HOMER3,CREM,SH2B1,NCOR2,DZIP3,EXOG,CNNM1,PLEKHO1,EPHA5,NOP56,PNMA2,GLYR1,POLL,ARHGAP19,SYNPO,KHK,KIF5C,MDM4,NF1,NUMA1,FSD1,PRKAR1B,RALGDS,ZFP30,BCAN,WDTC1,ZBTB43,DDN,ARHGEF9,KIAA0930,CRTC1,NSD2,SEMA3B" Drug 4359_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,MRTFA,AMT,ANK3,APBB2,APLP1,FAM131A,ATM,STX16,BAIAP3,CDC42,FOXN3,STOML1,CNTFR,SLC4A7,CSF1,SDC3,SORBS3,ERCC2,NCALD,ANKMY1,AGAP2,CINP,POLL,MAP4,MAPT,TM6SF1,MMP16,NLE1,RGS10,RASA3,ASAP3,LIMCH1,WDTC1,TSNAXIP1,ZBTB43,CLSTN2,PLCB1,ROBO3,KIAA0930,ZEB1,SZT2,ZNF34,TK2,HEY2,TMOD1,HIRA,VGF,ITM2C,KAT6A" Drug 5569_DN 2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ABR,NDRG2,PLA2G6,C1QTNF3,ALCAM,LTBP4,APOC1,ATM,SYNJ2,CBFA2T2,CNOT8,CRY2,RUBCN,EDRF1,DOCK4,C2CD2L,BAIAP2,FOXG1,TPK1,OGA,SEPT9,MALT1,CACFD1,RASSF8,ZNF862,NDUFA5,NF1,RETREG1,SLC25A23,MAPK8,CNNM2,ROM1,NEK11,RPS6KA2,WLS,SBF1,FAM214B,COA1,SMARCC2,ZHX3,EMC1,MAPK8IP3,ASTN2,PSD3,CDK20,PLPPR2,MICAL1,REEP1,EMSY,SEMA3B" Drug 5257_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASPHD1,PLA2G6,ALCAM,APBA2,DGKD,SEMA4G,ATM,CFLAR,SYNJ1,SYNJ2,GYG2,ARHGAP33,RAB28,TPP1,CNTNAP2,TBC1D5,MFAP3L,EXOG,DTNA,EZH1,FER,OGA,GAB1,RAB30,GNAS,GNG3,RASSF8,DHX35,NEK1,NF1,NFYA,NRGN,PCDH9,PRKAR1B,RAB3IL1,ZDHHC14,ZFHX4,CARF,TCP11L1,BTBD7,COA1,ZCCHC24,ZHX3,PLCB1,TMOD1,PARD3,CABIN1,CDK20,LMF1,GDPD5" Drug 3025_DN Acetaminophen [103-90-2]; Down 200; 26.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "RALGAPA1,C1QTNF3,AMT,MARK4,BACH1,BCL2L2,SYNJ1,SLC16A4,ARHGAP33,CLGN,FOXN3,CLCN4,QKI,SLITRK5,F5,ZNF589,FER,PRKAG2,FHL1,GABRA2,AHDC1,LILRA2,SPACA9,MAN1B1,NCKAP1L,MDM4,MID1,NINJ2,PIK3CD,PPARA,RGS10,NEK11,RASA3,ITSN1,SMARCC2,KDM4B,ZSWIM8,NCDN,ATP11A,PDLIM2,DMXL2,AHCYL2,THBS4,KAT6B,SMUG1,SSBP2,REEP1,SH3GLB2,EMSY,PARP11" Drug 3623_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "RBM10,NME5,C1QTNF3,DOC2A,AMT,APLP1,PPP4R4,SLC4A4,STX16,ATP6V0A1,BMP7,CLGN,NCOR1,DMPK,ATN1,DTNA,CNNM1,LRRC23,F3,BAIAP2,CINP,SLC2A6,IL6R,KIF5C,MMP16,MPP2,NRGN,PDE3B,EPN1,SLC25A23,TMEM104,RIPOR1,ZDHHC14,RGS12,KCTD17,GSTCD,RPH3A,FAM214B,SLC6A8,WDTC1,STX1A,TBCEL,SMG6,KIAA0930,PSD3,ZMYND8,FLRT2,MICAL1,KLC2,EVI5" Drug 4591_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "GAS7,BCAS1,ATP1A2,CADM3,FUBP1,CBARP,SOCS6,CHN2,AKAP5,CSF1,FEZ1,SDC3,ARHGEF4,RUSC2,DMPK,ATN1,DTNB,AASS,ETV1,BAIAP2,DENND2A,ERAP1,CNTRL,HSF2,IFI16,ITGA7,JAK2,TM6SF1,NEUROD1,NPTX1,PDE4A,MAPK10,RAB3IL1,CEP97,CCDC40,RGS10,RGS12,PBRM1,FBXW7,KCNIP1,ST6GAL1,LIMCH1,SPTAN1,PCDHGA10,CRTC1,AP4E1,TNS1,TRH,WNK1,PHTF2" Drug 6396_DN F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,SEMA6A,SYT13,MRTFA,DOC2A,TRMT9B,CNTNAP1,APC,PPP4R4,SPTBN4,CDK13,GYG2,CACNA1I,LDLRAD4,RUNX1T1,CDC42,GPR37L1,LY86,PICK1,NCOR2,PHF14,GREB1,RUSC2,EFNA3,MBNL2,TNK2,KIAA1109,FUT9,DISC1,PRUNE2,JAK2,MMP16,ADAM22,BCO1,CNOT4,NTRK3,SNTG1,PDE3B,PLCD1,PTAFR,PTHLH,FAT4,RGS12,STUM,DOK5,VAMP1,DMXL2,TNS2,HEY2,UBE3A" Drug 2239_DN Nocodazole [31430-18-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,KIDINS220,EPB41L5,APOC1,MADD,ASPH,ALDH4A1,CFLAR,SLIT2,PICK1,AKAP7,BAG4,CSF1R,FAM169A,RIMS3,CTIF,ARMCX2,TMCC2,CDON,RRAGB,FER,FGFR1,GAB1,GPER1,GPR37,SPACA9,GRIK5,GSTM5,IL6ST,ITPKB,MSI1,ADAM22,MYO7A,NEK1,NFYA,PCDH9,CDK18,LRP12,RGS10,SBF1,IL17RB,ZNF821,RCOR3,SNCA,CEP68,TACC1,KAZN,TMEM121,SPHK2,REEP1" Drug 2270_UP Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "MARK4,ATP2B2,ADGRB2,RGS11,CACNA1G,TAOK2,VCAN,SDC3,TOX,DNAH9,DRD1,NRN1,ST3GAL6,FOXF2,DLL3,B3GAT1,FYN,CHL1,SEPT9,GLS,GPD1,GRIK1,GUCY1A2,PTGDR2,KLF12,VSIG4,C2orf72,KCNMA1,MAG,MAP4,MID1,ENPP2,LRP12,SAMD9,RAB3IL1,FRMPD1,CPEB3,SLA,SLC6A9,SHANK2,SOX2,KIF21B,HECW1,THSD1,MAPK8IP3,ACSBG1,PSD3,HEY2,SEZ6L,TRPC3" Drug 6468_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NR0B1,SCAPER,CACNA1G,CCKBR,CDH8,CLGN,ZFYVE9,FAM189A2,CPS1,CREB5,CRMP1,TENM4,PDE4DIP,DZIP3,RIMS2,DAPK1,DYRK1A,SGK2,EGR3,EIF4G2,KHDRBS3,DENND2A,ERAP1,GFAP,GRM1,ITIH2,KCNC1,KIF5A,KIT,ADAM22,TAGLN3,NUMA1,OPCML,KCNK10,CAMKV,ZSCAN2,SUGCT,EMID1,SCN8A,CNKSR2,SLC1A2,SLCO1A2,MYH15,SNCA,FAIM2,WSCD1,ZEB1,TRIM2,THBS4,CLIP2" Drug 5078_DN Dapsone [80-08-0]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADCY6,MTUS1,PPFIA3,ALDH4A1,ATM,EIF4G3,BCL2L2,HIP1R,MAP7,CDC42,RCBTB2,ARMC8,NCOR1,VCAN,PPP6R2,GIT2,AK5,EGFR,HSD17B14,PLEKHO1,ETV1,EFCAB2,ATP2C1,GAD1,GNAS,IL6ST,MAPT,ZNF862,NFIX,PDE1C,PLCD1,PMS2,PTCH1,RAD51D,SCN8A,SIRT2,COA1,SPTAN1,ZBTB43,CEP68,VAMP1,PDLIM2,IQCE,TCF4,ZNF34,TK2,ZKSCAN5,XRCC4,TFIP11,EVI5" Drug 6501_UP Aminocaproic acid [60-32-2]; Up 200; 30.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "SPARCL1,LTBP4,MARK4,NRP2,BAIAP3,CFAP410,CBARP,FOXN3,TAOK2,CNN3,AKAP6,COL9A3,SNCAIP,BRINP1,RUSC2,ATN1,RCAN1,MBNL2,ERCC2,ST3GAL6,ZNF589,SORBS1,NSG1,TBR1,OGA,ALDH1L1,POLL,GPER1,IL1RAPL1,GUCY1A2,HPSE2,KIF5A,MYO7A,TREM2,PC,PLTP,MAPK7,PTX3,RGS12,SCN2B,SMTN,ARHGEF40,ARC,WSCD1,SLC44A1,THRA,CABIN1,WNT7A,XRCC4,SLC30A3" Drug 6133_UP Verteporfin [129497-78-5]; Up 200; 2.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "SYN3,FZD9,BCAR3,MARK4,RIPK1,SYNJ2,MTMR3,CH25H,HIP1R,CBARP,CHN2,SLIT2,CREM,CSF1,DLG3,EXOG,HS3ST2,ABCC9,ST8SIA3,EDNRA,MBNL2,VPS13B,DLC1,FGFR1,FOXG1,NSG1,GAP43,GATM,PRUNE2,CACFD1,NXPH3,ICA1,SCIN,KCNJ5,MT1M,NCAM1,NPTX1,KCNK10,SYTL2,RFX2,CARF,PNMA8A,SYNDIG1,FRMPD1,TMCC1,SPTAN1,TBCEL,CRTC1,WNT7A,MKRN3" Drug 1494_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "AP2A2,C1QTNF3,CDC42BPA,ARHGDIG,CADM3,CFLAR,RAB29,BAIAP3,CDH8,LARGE1,QKI,MFAP3L,HS3ST2,DTNA,EFNB3,MBNL2,DMTN,LRRC17,F3,PTK2B,TUBB4A,OGA,ALDH1L1,SRCAP,PRRC2B,GRB10,DHX35,KIFC3,MAP4,MBD1,MMP16,NACA,PIK3CD,SEPT4,POLG,POU6F1,PRODH,GON4L,PTPRH,RAB3A,ATG16L1,RNASEL,DOK5,VPS13A,POPDC3,EXOC7,CHST8,THRA,ITM2C,NUP214" Drug 6007_DN Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "PLA2G6,APBA2,APBB2,APLP1,BCAS1,SLC2A11,KIF1A,SYNJ2,SCAPER,LDLRAD4,BTRC,AP4M1,UBE2L6,QKI,FEZ1,CNTNAP2,EDRF1,RABGAP1L,DNM2,DRD1,LRRC23,ZNF589,FAM49B,SRCAP,MALT1,GLS,HSF2,JAK2,MMP16,NDUFA5,NF1,CNOT4,SAMD9,ARHGEF10L,ITSN1,ANKRD6,ZNF365,SMTN,RAB3GAP1,CXXC4,SNCA,KDM4B,CDK19,MCF2L,TK2,ZKSCAN5,PLPPR2,VIPR2,EMSY,KCNAB1" Drug 5318_UP Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASPHD1,ABHD6,LTBP4,APOC1,BCAS1,ARRB2,ASPH,ALDH4A1,ATP6V0A1,MTMR3,HIP1R,USP2,ADGRG1,PDE4DIP,SDC3,GREB1,EFNB3,EGR3,NCALD,F3,FGFR3,GLS,DIDO1,ITPKB,JAK2,KCNN1,KHK,LSS,MATK,MX1,NF1,NUMA1,PC,LRP12,PPP5C,CNNM2,ZSCAN32,PEX5,RAB3A,RAB3IL1,RALGDS,SYBU,ZHX3,NXT2,FCHO1,DNMBP,PDLIM2,FAM155A,LMF1,NAV2" Drug 2104_DN Flufenamic acid [530-78-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADCY6,CDC42BPA,CNTNAP1,APBB2,APLP1,APP,MARCH3,MPDZ,LHX2,NMT2,HINFP,PDE4DIP,GIT2,DMTF1,IRAK4,MFSD10,GAD1,GLUL,RNFT2,AGFG1,MIA2,NASP,SLC11A2,PDCD2,CDK14,PIK3R1,POLG,SAMD9,GON4L,GTDC1,RIC8B,RPS6KA2,PAQR6,SAFB,MAPK12,SBF1,SUPT20H,PPP1R9A,SLC1A3,EPN2,KDM4D,CDK5RAP2,PDZD2,ST5,TTBK2,ARHGEF9,TCF4,SIN3B,AHCYL2,AAAS" Drug 2742_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ACHE,APBA2,CACNA1G,CDH2,CHRNA4,DNAJB5,AKAP6,NCOR2,PDE4DIP,DSCAM,SRPK3,SIGLEC8,GFER,RUNDC3A,GNAL,GRK4,GRIK2,SOX21,HPSE2,SCIN,KCNC1,KCND3,MAPT,MBNL1,MGAT3,AFDN,ADAM22,MYO6,NPY,PPP1R1A,RGS4,TTLL7,NUDT11,SUGCT,CCDC92,RPH3A,EPN2,KANSL3,SOX2,SPART,CLSTN2,ASTN2,SYT5,TIAM1,TRIO,TRO,XRCC4,SEMA3B,FAM13C,JPH3" Drug 4564_UP "Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASPHD1,SYN3,ADORA2A,AGT,ADGRF5,LTBP4,FAM135A,APC,ASCL1,RUNX1T1,NCOR2,ABCG1,SUSD5,CNTNAP2,DAPK3,BRINP1,RABGAP1L,DRP2,ATN1,DSCAM,SRPK3,PIPOX,CORO2B,ST3GAL6,CAMSAP1,IRF8,IL12A,MAPT,NELL2,NOVA2,PBX1,PCDHGC3,PDE3B,PDE4B,RETREG1,SPATA6,RGS12,SORCS3,KIF13A,KIF21B,DDN,MAPK8IP3,KLHL4,TK2,TMPRSS5,SPHK2,NAV3,FAM13C,NUP214,GAN" Drug 5577_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "DPF1,SYN3,ACTN2,ARID1A,ADORA2A,ATP2B2,KIF1A,GYG2,CA4,CACNG1,HAP1,CAMK2B,USP2,ARHGAP33,TAOK2,HAPLN1,NTM,DRD1,DYRK1A,EDNRA,EFNB3,ELAVL4,ELN,NRN1,ZNF589,ATXN2L,MAOB,MOBP,MYH6,NNAT,LRP12,MYH14,SYNDIG1,SALL1,DOCK10,SLC9A5,SNCA,KIF21B,SPTB,IQSEC2,SAMSN1,SYN2,ROBO3,DOCK9,DNAH7,ZNF34,TPM2,TRPC3,PDIA2,FLRT2" Drug 4540_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASPHD1,CDK10,ARRB2,ALDH4A1,BAIAP3,CAST,MAP7,RAB28,RUBCN,MFAP3L,PLPPR4,DLG3,DNM2,PLXNC1,MRNIP,EN2,ETV1,EZH1,F3,WAC,FGFR1,SRCAP,C1QL1,MSL3,GPR17,GRK4,HLF,SYNPO,MAP4,MMP16,MX1,CNOT4,ODF2,PIK3R1,CNNM2,RIPOR1,PID1,RAD52,RPS6KA2,MAPK12,ZFP30,DZIP1,WDTC1,PHLDB1,WSCD1,CRTC1,TIAM1,RUNDC3B,LMF1,PHTF2" Drug 5394_DN Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "APP,ALDH7A1,SYNJ2,ADGRG1,PLAA,AKAP7,NECTIN3,PDE4DIP,DAPK3,FBXL5,SMG7,ING4,ZNF589,FGFR1,GALC,GART,GCNT2,GLYR1,GPER1,GRIK5,IPO5,MIA2,KITLG,ADAM22,NEK1,NF1,NRGN,NUMA1,PDE4A,SLC25A23,LRP12,PRKAR1B,RALGDS,ATG16L1,RGS12,MAPK12,SH3BP2,SLC1A7,KIF13A,WDTC1,FNBP1,CLSTN2,PHLDB1,PLCB1,TK2,CABIN1,VAV2,VLDLR,GDPD5,PHTF2" Drug 2697_DN fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,PLA2G6,DOC2A,ANK3,MPDZ,CACNA1G,RCHY1,CREM,CSF1,CSF3R,PPP1R16B,ARHGAP32,TBC1D5,DSCAM,DYRK1A,CNNM1,SIDT2,FAM13A,PLXNC1,ING4,PTK2B,CAMSAP1,TRAF3IP2,WASF3,AHDC1,ZNF276,ITGAM,MAPT,MDM4,MEF2C,MYO6,NFYA,NPR2,OLR1,PDE4A,PIK3CD,PMP22,RXRA,AMBRA1,IZUMO4,LHPP,PLCB1,TCF4,TCF7L2,AHCYL2,TMOD1,TNS1,SMUG1,CLIP2,SPHK2" Drug 6887_UP SB 202190; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,BIN1,APOC1,PPFIA3,ASPH,ALDH4A1,RIPK1,GYG2,CBFA2T2,CNOT8,ZFYVE9,WHRN,COL4A5,SLC4A7,SLC4A8,BAG4,RIMS3,SPOCK2,LYPD1,EFNA3,EFNB3,EGFR,ZNF589,CGREF1,RUNDC3A,NR3C1,INPP1,KCNH2,MATK,MEF2C,ADAM22,ZNF862,NF1,SERPINE2,PPARA,MAPK7,ZSCAN32,PYGM,RFX2,ROM1,TCP11L1,ZFP30,PPP1R9A,KDM4B,TRIM2,CDK20,CADM1,LMF1,ITM2C,MPPE1" Drug 265_DN prednisolone; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ASIC1,KDM5D,ARID1A,ADRB2,AK2,CNTNAP1,APBB1,AQP6,ASCL1,ATM,FGF17,CFAP410,CD86,ARHGAP33,SLC24A2,ENTPD4,DCAF8,DBT,RABGAP1L,DRP2,ATN1,DYRK1A,SORBS3,EFS,EYA1,SCARA3,SEPT9,ZNF276,GRIN1,ATXN2L,VSIG4,IRF8,KCNA1,KCNJ5,KCNMA1,L1CAM,CDK14,EPN1,MAPK8,RIPOR1,CEP97,TTLL7,KLHL11,EMID1,TROVE2,POGZ,SST,GPR161,PLPPR2,LAMP5" Drug 7541_DN 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADCY6,NME5,AMPD3,CFLAR,BAIAP3,NCOR1,FAM169A,DAPK3,GIT2,DBT,MFAP3L,FBXL5,FEM1B,ERCC2,F8,FGFR1,SCARA3,IQCG,EFCAB2,FYN,GAB1,HBS1L,TMEM8B,GNG3,GNG4,IRAK3,SMAD1,MITF,MX1,NF1,NFYA,PDE3B,PLCD1,MTRF1L,SNRK,WDR25,FAM184A,GTDC1,SH3BP2,SLC1A7,KIF13A,WDTC1,INKA2,CEP68,PLCB1,CRTC1,TMEM121,TGFBR3,ZKSCAN5,MVB12B" Drug 1687_UP Hydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,MRTFA,AMH,KCNAB2,APBB2,LDLRAD4,PLEKHB1,ZFYVE9,CLU,SULT4A1,MFAP3L,CDON,SORBS3,ING4,HSD17B14,RRAGB,REEP2,FGFR1,PRELID3A,ERAP1,TXNL4A,GPR19,CNTRL,SPACA9,GRIK5,GSTM5,TJAP1,MBD1,MGAT3,MOBP,NFYA,CNOT4,PCDH9,LRP12,MAPK8,PRPH,RGS10,NEK11,SUPT20H,PPP4R3A,BTBD7,USP33,EMC1,IQSEC2,CEP68,ARC,EXOC7,TCF7L2,KCNK12,ZNF74" Drug 1696_DN Norethynodrel [68-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ALAD,BCAR3,LTBP4,CDC42BPA,SHROOM2,CDK13,RIPK1,SYNJ2,CAMK2G,AKAP7,CTNND2,PPP6R2,HDAC4,GIT2,SUGP2,VPS26C,TESK2,FGFR3,FAM49B,CSPG5,GAA,TRAF3IP2,SRCAP,ITPKB,MAP4,NPR2,SLC11A2,SLC25A23,SIDT1,NEK11,GALNT10,ITSN1,SLC20A2,ZSWIM8,ERC1,ELOVL4,COBL,TACC1,MCF2L,EXOC7,IQCE,TBL1X,KIAA0930,HIRA,PLPPR2,VAV2,LMF1,KLC2,MAP3K12,SMIM8" Drug 2855_UP (R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "MTUS1,NME5,BIN1,APC,PLA2G4C,MARK4,ATM,ATP2A2,CFLAR,GYG2,ZFYVE9,PDE4DIP,GREB1,GPRASP1,RASSF2,RIMS3,RABGAP1L,ING4,ELAVL3,VPS26C,EZH1,FGFR1,FAM49B,PRELID3A,RND1,FERMT2,GRIK5,GSN,IL6ST,INPP5B,KHK,MAOB,MEIS2,MX1,ZNF862,NUMA1,SERPINE2,ZNF493,SLC1A2,KANSL3,SMARCC2,ZNF423,IQSEC2,MAPK8IP3,DMXL2,TK2,TRPC1,VAV2,LAT2,REEP1" Drug 825_UP rottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "BIN1,CDC42BPA,CDC14B,ATP2B2,KIF1A,NRG2,RIMS2,GIT2,TRAPPC9,SLC12A6,ST8SIA3,AASS,EPB41,EFS,F3,ST3GAL6,FGFR1,GPR153,FYB1,GABRA2,SIGLEC8,LPAR4,GRM1,IRAK3,SYNPO,KCNC1,KCNMA1,ADAM22,NUMA1,PCSK5,SIDT1,PTHLH,FAM120C,RAD52,ZCWPW1,KHDRBS2,KLHDC8A,FRMPD1,ZNF365,PKNOX2,BTBD7,WDTC1,TSNAXIP1,PEG10,VAMP1,SYT5,WSCD1,VAV2,VLDLR,NLRP3" Drug 6695_UP Felodipine [72509-76-3]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "DPF1,ADD2,NME5,ADGRF5,LTBP4,PPFIA4,APAF1,APC,CDK13,ASTN1,ADGRB2,MAP7,CBS,CHRNA4,TAOK2,CLCN4,HAPLN1,EFNA3,MBNL2,PLXNC1,ST3GAL6,FGFR1,GRM8,HTR5A,ITPKA,PACRG,MDFI,KITLG,NTRK2,PCDH9,ENPP2,MINDY2,MAPK8,GON4L,ELOVL2,ZSCAN32,RGR,RPS6KA2,SLC11A1,KIF13A,PDZRN3,EMC1,SRPK2,TROVE2,CRTC1,HIRA,ZNF24,SLC17A7,EPM2A,GAN" Drug 2783_UP Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "NDRG2,NME5,ALCAM,LTBP4,CDK13,MARK4,GYG2,CACNA1I,HAP1,PICK1,CNTN1,INTS1,DTNA,MBNL2,EN2,FHL1,DPYSL4,PDLIM5,GABRG2,LUZP2,GPR22,GPER1,GSN,ATXN2L,KCNN2,KHK,MAP4,NRGN,PDE4B,SERPINE2,FA2H,PRODH,KCTD17,RPS6KA2,EMID1,ZNF821,CPEB3,SMARCC2,PEG10,IQSEC2,ATP11A,KAZN,SMG6,KIAA0930,TCF7L2,PCDHA5,SLC44A1,CA14,HIRA,SYNC" Drug 5639_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.66E-04 1.00E+00 2.37E-03 2.69E-02 50 196 "ADRA1D,ALCAM,BIN1,PPP4R4,MARK4,CACNA1I,CLGN,CRLF1,ATRNL1,EDRF1,DOCK4,DBT,MFAP3L,EFNA3,EFNB3,RRAGB,INPP5K,ALDH1L1,GCNT2,GLYR1,RAB30,NR3C1,IL6ST,INPP1,LMO2,MAP4,NEK1,CNOT4,SERPINE2,EPN1,PPARA,MINDY2,SAMD9,ZSCAN32,FAM214B,SIRT2,DOK5,TROVE2,TTBK2,PLCB1,DICER1,SLC44A1,TMOD1,TNS1,TRPC1,KCNK12,ZFP37,ZIC3,SLC17A7,PHTF2" Drug ctd:D020106 Acrylamide CTD 2.67E-04 1.00E+00 2.38E-03 2.71E-02 51 201 "ACHE,ATM,ARHGEF7,SCARB1,CLTC,ABI1,EGFR,ERBB2,PTK2B,TUBB3,FGFR1,GAP43,CPLX2,GFAP,GLS,GLUL,GRIN1,GUCY1A1,GUCY1B1,IGF1,ITGAV,KCNQ2,KCNQ3,KIT,STMN1,MBP,MYBPC1,NCAM1,NEFM,NFE2L2,NOS1,PDCD2,PGAM2,PIK3R1,PRKAR1B,MAPK3,MAPK8,MAPK9,PTK2,RYR1,RYR3,SLC1A3,SLC14A1,SYP,SYT1,TAC1,TJP1,PIK3R5,TPM1,TPM2,ZNF24" Drug CID000001985 amoebal Stitch 2.68E-04 1.00E+00 2.39E-03 2.72E-02 16 41 "MYH7B,RUNX1T1,RGN,TUBD1,TUBB3,TUBB4A,AGAP2,TUBA8,CRCP,TUBA1C,TUBB2B,ACER3,WDR7,TK2,TUBB1,TUBA1A" Drug CID005287682 AC1NRA3O Stitch 2.68E-04 1.00E+00 2.39E-03 2.72E-02 16 41 "ACLY,ADCY6,ANXA7,APAF1,DYNLL1,CBR1,ABCG2,CNTN1,TNK2,EFEMP1,HP,HPR,NDUFA5,NPY,PLP1,RTN4" Drug CID000010789 tropolone Stitch 2.72E-04 1.00E+00 2.43E-03 2.76E-02 19 53 "ARSE,DBT,TUBD1,TUBB3,TUBB4A,TUBA8,LOXL3,TUBA1C,TUBB2B,LRRC4B,MAOB,TBL1X,TF,PDSS1,TRO,TUBB2A,TUBB1,SHD,TUBA1A" Drug CID000015910 chlorothalonil Stitch 2.77E-04 1.00E+00 2.47E-03 2.81E-02 43 162 "AP2A2,SEMA6A,APAF1,NRP2,DBI,DYNC1I1,ATN1,RCAN1,EN2,RCAN2,ERBB2,F8,PPP1R1B,FOXG1,FOLH1,GALC,PPARGC1A,KIRREL3,LYVE1,TCERG1,NR3C1,PACSIN2,HSP90AA1,RBPJ,NCF2,NELL1,NELL2,NPTX1,OGG1,PENK,PACSIN1,FSD1,QDPR,FBXW7,ATXN7,FOXRED1,ARX,SLC1A3,SHANK2,CYB561A3,TMEFF2,SEMA3B,JPH3" Drug CID000000342 m-cresol Stitch 2.85E-04 1.00E+00 2.54E-03 2.89E-02 26 83 "ARHGDIA,CHRD,LDHD,CACNA1A,CARS,DCLK1,APPL1,ATN1,ELAVL2,F3,SCARA3,GPT2,GRIA1,GRIA2,GRIA4,IL12A,MAG,OMG,RNH1,ACER3,TMPO,TPM1,TPM2,TPM3,TPM4,TTPA" Drug 3740_UP Gossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-04 1.00E+00 2.63E-03 3.00E-02 47 182 "ADRA1D,OGT,PPP4R4,ASPH,RASL11B,BMP7,SYNJ1,CARS,CBS,ARHGEF2,CHI3L2,EPS15L1,CLCN4,MAGI2,RCAN1,ECM2,FRY,EFNA3,CELSR3,EGFR,MBNL2,ENO2,POLL,FERMT2,MARK1,MIA2,MMP16,NF1,NFYA,CLDN11,PDE4D,PFKFB3,PFKFB4,PTPRB,PTX3,RAD52,BEND5,ZNF821,HECW1,ARC,CRTC1,TK2,ZMYND8,CA14,VLDLR,XRCC4,SPHK2" Drug 2688_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.96E-04 1.00E+00 2.63E-03 3.00E-02 47 182 "ASPH,ATP2B2,ATP2B3,AZGP1,CDH10,CDO1,LHX2,NRG2,CREM,SIPA1L1,PDE4DIP,ZNF337,DGKG,DNAJC6,ATN1,ABCC9,HIPK3,MBNL2,AASS,ATP8A1,CAP2,ATP2C1,RASSF8,HNMT,HPCA,IL6ST,KCND3,NF1,PDE4B,PLCD1,MBOAT7,PRKACB,SUGCT,HSPA4L,CNKSR2,SLC15A2,ZNF415,PEG10,PLCB1,SYN2,PCDHGA10,CHST8,CRB1,SEZ6L,ZBTB38,EVI5,FXR1" Drug 4376_DN Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.96E-04 1.00E+00 2.63E-03 3.00E-02 47 182 "ADD3,SEMA6A,ALK,APC,PDE8B,ATM,SLIT2,AKAP12,PDE4DIP,DZIP3,DMPK,DSCAM,EFNA3,EFNB3,DLC1,RACK1,FOXG1,EVL,GHR,STON1,GPER1,GPR37,CNTRL,BRINP3,KCNJ3,MEIS1,NASP,PIK3R1,PKIA,SIDT1,CEP97,CXXC4,LIMCH1,PHLDB1,TACC1,MCF2L,KIAA0930,PSD3,TK2,HEY2,CDK20,RUNDC3B,HIRA,FLRT2,ZIC3,EMSY,ITM2C" Drug 6663_UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.96E-04 1.00E+00 2.63E-03 3.00E-02 47 182 "ADORA1,NR0B1,CDC14B,PDE8B,N4BP2L1,AZGP1,CFLAR,BMPR1B,IL33,HAP1,MAP7,RUNX1T1,TMEM59L,CREM,AKAP12,PDE4DIP,CTH,PYGO1,PITPNC1,ARNT2,DSCAM,STX2,ETV1,FGFR1,NSG1,GPM6A,GRIK3,PADI2,HSD17B1,KCNN1,ADAM11,PDGFRA,PFKFB4,SMOX,PMP22,PTHLH,RYR1,SLA,SHANK2,RBM26,COBL,SEMA4A,MCF2L,TBL1X,PRDM2,PRDM10,FAM13C" Drug CID000001826 5-HIAA Stitch 2.98E-04 1.00E+00 2.64E-03 3.01E-02 36 129 "ABAT,ACHE,KDM5D,BRAP,ALDH7A1,CHGA,DZIP3,DRD1,ENO2,EPHA5,ZMYND10,GAD2,LOXL3,LNX1,MCHR1,CIT,HTR2A,HTR5A,KCNA1,KCNA2,MAOB,MID1,NDP,CNOT4,NPY,PAH,CNTN3,QDPR,SLC1A3,SST,SSTR1,SSTR2,ABCC8,PJA1,TRH,UBE3A" Drug 5841_UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.99E-04 1.00E+00 2.64E-03 3.01E-02 48 187 "ADCY6,ADORA2A,ALDH4A1,SLC4A4,CFLAR,BAIAP3,NRXN3,CLCN4,CPS1,CREB5,AKAP12,VCAN,PDE4DIP,DZIP3,DCAF8,ZNF337,GIT2,SGK2,NRN1,ACSL4,BAIAP2,ALDH1L1,GSTM5,TAGLN3,ODF2,OXTR,RAB3IL1,GSTCD,NEK11,TCP11L1,ASAP3,AMBRA1,ABLIM3,LIMS2,ELMO2,TMCC1,DOK5,ARHGAP26,RAP1GAP2,NXT2,ANKRD12,WWC1,IQCE,ZFPM2,TRIO,VIPR2,WNT7A,RNF146" Drug 3037_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.99E-04 1.00E+00 2.64E-03 3.01E-02 48 187 "ABHD6,SLC12A5,MTUS1,KIAA1324,APBA2,DDO,ASCL1,DNAH17,ATP1A3,ADGRB3,NRP2,FUBP1,REPS2,CHN2,CREM,AATK,SIPA1L1,CNTNAP2,USP6NL,DOCK4,ARNT2,CNNM1,STX2,EYA1,REEP2,CORO2B,GABRG2,GALC,MYOZ2,KCNMB4,PTGDR2,HNMT,MPP2,NEUROD2,NOVA2,PDE4B,KLHL11,RYR1,SLC1A7,SMTN,SLC11A1,TMCC1,TACR1,PCDHGB6,SLC35G2,SLC13A3,PMEPA1,ADAMTS9" Drug 4580_UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "AGT,TRMT9B,CDK13,MTMR3,CAMK2B,ARHGEF2,CHRNB2,STOML1,CREM,CREB5,AKAP12,SUSD5,VCAN,CTNND2,SPOCK3,SRGAP3,EGFR,PLXNC1,LRRC23,F5,EFEMP1,DPYSL4,TRMO,MYOZ2,LYVE1,GPM6B,GRM7,IL6R,IL12A,KCNMA1,LAMA2,LSS,AFDN,PALM,NLE1,STRN3,ELOVL2,PTK2,CCDC102B,ZFP2,TNIK,RAP1GAP2,MAPK8IP3,SYT5,ZMYND8,UBE3A,LAT2,REEP1,NAV2" Drug 4454_DN thioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "ABR,AP2A2,C1QTNF3,LTBP4,SEMA4G,ADGRB2,MYRF,CBFA2T2,LHX2,KIAA1549L,IQCK,COL9A3,SLC4A8,SLITRK5,CNIH3,MED24,KLHL3,FAM13A,IRAK4,NCALD,FGFR1,IQCG,FYB1,SRCAP,POLL,GPER1,CNTRL,KHK,MAPT,GIT1,NDP,NF1,NUMA1,PBX1,RAD51D,RAD52,RGS10,GSTCD,ARHGEF40,SMARCA4,UNC5B,DDN,KIAA1107,WSCD1,TMEM121,TNS1,UGT8,TRIM9,PHTF2" Drug 4303_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "ACHE,ACTN2,AMH,APAF1,CDK10,ASCL1,RASL11B,NRP2,SYNJ1,LDLRAD4,KALRN,ADGRG1,RAB28,CLCN4,IFFO1,EDRF1,RIMS3,CTIF,ATN1,SORBS3,TUBB4A,FGFR1,FHL1,CAMKK2,GAB1,GAD2,GLYR1,RAB30,PRUNE2,IL12A,KCNB1,NELL2,NRGN,NUCB1,CDK18,PDE4A,PFKFB4,MAPK7,ENOX1,ABLIM3,WDTC1,SOX11,NXT2,KLHL4,SZT2,VGF,PRDM2,NAV2,PARP11" Drug 5401_DN Dextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "RALGAPA1,APBB2,APC,APLP1,PPFIA3,ARHGDIG,BRINP2,ALDH4A1,CACNA1D,ADGRG1,B4GALT6,SLIT2,AKAP7,MICAL2,EDRF1,JAKMIP2,DNM2,SIDT2,SUGP2,ING4,EPB41L1,ZNF589,FGFR1,FHL1,CGREF1,OGA,GCNT2,GNG4,IL6ST,KCNH2,MIA2,KITLG,ZNF862,CNOT4,SLC25A23,ELOVL2,RAB3A,RAB3IL1,RALGDS,SLC1A7,SLC20A2,TRIM2,TMEM121,AP4E1,TK2,VAV2,SEMA3B,SMIM8,PHTF2" Drug 5812_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "CDC42BPA,CDK10,SEMA4G,CFLAR,MAP7,CNOT8,ARMC8,CPS1,CREM,ENTPD4,AKAP12,SIPA1L1,CTH,DCAF8,GIT2,PITPNC1,ARMCX2,CNIH3,DLG3,CDON,EDNRA,ATP8A2,TAGLN3,NCAM1,NF1,ODF2,OGDH,OPCML,PDYN,SMOX,PTHLH,GSTCD,ZNF821,SLC8A1,ELMO2,IFT122,TMCC1,WDTC1,SYN2,TACR1,TCF4,DOCK9,OSBP2,VGF,SEMA3B,SLC17A7,MPPE1,PLSCR4,EPM2A" Drug 6875_UP 0175029-0000 [211245-78-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "ACTN1,NDRG2,ADRA1D,ADGRF5,AMH,PKP4,ALDH4A1,STX16,FUBP1,LDLRAD4,CAMK2B,RUNX1T1,NEURL1,ASIC3,SLC22A6,HAPLN1,HIPK3,SORBS3,LRRC23,KIAA1109,HBS1L,DISC1,SEPT9,C1QL1,GLYR1,GRM5,GRM8,HSF2,KCNMA1,MX1,NACA,NOVA2,FSD1,PEX5,ZSCAN2,ROM1,PAQR6,SOX10,SPTAN1,NXT2,MAPK8IP3,ATP11A,ROBO3,AHCYL2,TPM2,VIPR2,VSNL1,LAT2,NSD2" Drug 7218_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.01E-04 1.00E+00 2.64E-03 3.01E-02 49 192 "KIDINS220,AK2,AMPD3,APC,NUMB,ALDH4A1,RGS9,SYNJ1,LDLRAD4,CACNB4,RCHY1,SEC14L5,TOX,SLC12A6,DTNA,CNNM1,DLC1,FER,FYN,GABRA1,SRCAP,GRK4,GRB10,GRM8,ELOVL5,KCNC1,MATN3,MITF,MPP2,ZNF862,NELL2,PFKFB4,NLE1,POU3F2,PKN2,C1orf54,KHDRBS2,ASAP3,SYBU,RPH3A,KANSL3,SNCA,UNC5B,WSCD1,PCDHGA10,TEX15,SLC44A1,LILRA4,TPM1" Drug 3412_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "DOC2A,AMT,PPFIA3,CDC14B,CDK10,CDK13,ALDH4A1,SLC2A11,FUBP1,CFAP410,CACNB2,CPS1,SDC3,TBC1D5,ATN1,FEM1B,EGFR,EIF4G2,EML1,HSD17B14,FLNC,DPYSL4,TXNL4A,GLYR1,KCNQ3,KHK,MIA2,LYRM9,PALM,CDK18,PFKFB2,RALGDS,ZDHHC14,RGS3,RGS10,RGS12,SHANK2,UNC5B,MAPK8IP3,PHLDB1,PLCB1,EXOC7,PIK3R5,TPD52,RUNDC3B,MICAL1,XRCC4,ZFP37,ZBTB14,PRDM10" Drug 5860_UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "RALGAPA1,ACTN2,MTUS1,CDK13,ST3GAL5,CD86,SYNGR3,ASIC3,CLCN4,DNAJB5,VCAN,PDE4DIP,ATN1,DYRK1A,ETV1,SORBS1,GATM,MSTN,C1QL1,GPD2,ADAMTS13,HPCA,KCNJ4,KCNMA1,KPNA5,NF1,NOVA2,PIK3R1,SPATA6,PPP2R2B,CNNM2,C1orf54,RGS12,PNMA8A,SBF1,ASAP3,FAM214B,SNAP25,SOX2,DOK5,SPTB,ATP10B,CEP68,VAMP1,SEMA4A,TRO,TRPC1,TRPC3,WIPF1,KCNK12" Drug 5081_DN Perhexiline maleate [6724-53-4]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARID1A,ANK3,ADAM15,ARHGEF7,SCAPER,BTRC,CBFA2T2,CHN2,CLCN4,CSF1R,PPP6R2,DNAJC6,RUSC2,PARD6A,RABGAP1L,EDIL3,EFNA3,MBNL2,LRRC23,EPHA5,SPEG,ETV1,TRMO,DENND2A,GAD1,SRCAP,GLS,CNOT4,PBX1,PLCD1,FAT4,GTDC1,MAPK12,WDR37,DHX30,WDTC1,THSD1,SS18,VAMP1,ARHGEF12,CRTC1,ZNF34,BEX4,CABIN1,TPM2,PLPPR2,LAT2,MAP3K12,VPS35L,FZD3" Drug 6249_UP Thiorphan [76721-89-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADD2,PLA2G6,PTCH2,SLC2A11,BCL7A,KSR1,MTMR2,CA4,CCNT1,CBFA2T2,CDH2,PLEKHB1,ARHGEF10,DCT,MAMLD1,EDNRA,EPB41L1,SEMA4D,GABRA2,GLYR1,CACFD1,GSN,KCNF1,KCNJ5,NTRK3,PDE3B,PMP2,SAMD9,KHDRBS2,RGS12,DCUN1D2,RASA3,RBM34,ZCCHC24,EMC1,MAPK8IP3,ARC,TCF4,PCDHA5,TMEM121,CABIN1,TNS1,PLPPR2,LMF1,SLC13A3,XRCC4,ZNF74,SYNC,SCG2,PHTF2" Drug 4744_DN Tropicamide [1508-75-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG2,ADRA1D,MRTFA,TRMT9B,AMT,APC,GAS7,ALDH7A1,CFLAR,MTMR3,CACNA1D,CBFA2T2,NEURL1,SIPA1L1,CNTNAP2,RIMS2,EDNRA,EIF4G2,KAT8,FGFR1,GCNT2,GLYR1,STON1,GRM8,IL6ST,MID1,MMP16,NFYA,CNOT4,PDE4A,SERPINI1,RETREG1,NLE1,SAMD9,RGS12,FAM214B,DOP1A,ZNF423,ZC3H13,MAPK8IP3,PLCB1,PCDHA5,CHST8,THRA,CDK20,HIRA,FAM155A,SPHK2,EMSY,EPM2A" Drug 387_UP "estradiol, USP; Up 200; 0.01uM; HL60; HG-U133A" Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG3,NDRG2,DNAH17,RASL11B,SLC4A4,ADGRB1,CA12,SLC25A14,ENTPD6,KCNAB3,LARGE1,DLGAP1,CLTB,RAB26,CRYM,GIT2,EPHB1,BAIAP2,SEC23B,TRMO,INPP5K,NEU3,CACFD1,NR3C1,AP4S1,PADI2,L1CAM,MX1,SLC11A2,OCRL,PDCD2,PLCB2,PRKAR1B,MAPK3,PLEKHB2,DPF2,ATXN1,SGK1,DOCK10,SHMT2,SNAP25,KDM4B,UHRF1BP1L,SPART,STX1A,KAT6B,VIPR2,WNT7A,KCNAB1,MPPE1" Drug 1774_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; HL60; HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARRB2,CDK13,ASPH,SLC4A4,MYRF,RUNX1T1,CLDN10,EPS15L1,SEC31B,PPP1R16B,PPP6R2,ARHGAP32,TRAPPC9,ATN1,IGSF6,EZH1,KIAA1109,IQCG,LILRA2,GPR19,CACFD1,ICA1,IL11RA,LAMP2,GIT1,PTOV1,NINJ2,NPPA,OGG1,PALM,PLEC,MAPK3,PTPRO,RGS3,RGS12,RXRA,ATXN7,NTNG1,ARHGEF40,ELMO2,KDM4B,WDTC1,UNC5B,THSD1,SEMA4A,TBL1X,VIPR2,LAT2,WIPF2,ST7" Drug 5618_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADCY6,SPARCL1,SYT13,AMPD3,BIN1,SEMA4G,ASCL1,PROM1,KALRN,CLDN10,NEURL1,COL9A3,CPS1,CRYM,TOX,RASSF2,CTIF,C2CD2L,EGFR,EN2,C1orf61,NSG1,SIGLEC8,RUNDC3A,GPM6A,VWA5A,CD200,NOVA2,PC,MAPK10,TTLL7,SYNDIG1,ITSN1,ASAP3,SLCO1A2,LIMCH1,ZC3H13,AJAP1,TACR1,WSCD1,TF,HEY1,RIMBP2,LILRA4,CHST5,TTPA,UCHL1,FLRT1,SPHK2,MVB12B" Drug 3894_DN Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NME5,DOC2A,BIN1,GAS7,APLP1,SLC2A11,ALDH7A1,CA4,SCARB1,ZFYVE9,CSF1,CSF1R,RIMS2,USP6NL,EDRF1,DAPK3,CTIF,EXOG,EFNB3,HSD17B14,SCML2,ZNF589,FYN,HBS1L,GCNT2,C1QL1,GPD2,LMO2,MATK,KITLG,NF1,NTRK2,PIK3CD,MAPK8,CCDC40,MYH14,RASA3,SH3BP2,DOCK10,BTBD7,CDK5RAP2,WDTC1,ATP11A,EXOC7,SMG6,TNS2,TGFBR3,SLC44A1,WNK1,ST7" Drug 5885_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "RALGAPA1,ABCD2,PPP4R4,KIF1A,ST3GAL5,BAIAP3,BTRC,CDC42,DAPK3,MFAP3L,ABCC9,EGFR,HSD17B14,TUBD1,LRRC23,ZNF391,FGFR1,CAMSAP1,PDLIM5,TMEM8B,SEPT9,LILRB4,GPR22,GRM8,BACH2,ELOVL5,SCIN,KCNB1,MDFI,MOBP,ADAM22,PLCD1,MINDY2,WDR25,PTPRB,PTPRN2,FAM120C,ASIC4,BTBD7,TMCC1,DOK5,NMNAT2,SYN2,TACR1,KIAA1107,TCF4,KIAA0930,SLC44A1,SCG2,TIGD6" Drug 2559_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADRA1D,PLA2G6,APC,NCOA1,CDK5R1,HIP1R,RAB33A,TPP1,QKI,BAG4,CPS1,CREM,ZNF337,DBT,SMG7,DTNA,SIDT2,PDLIM5,OGA,USP19,TXNL4A,COPS8,GNG3,LILRA2,MAP4,MEF2C,MIA2,PLEC,PTK2,C1orf109,FAM184A,RET,RNASEL,PCMTD2,FOXRED2,ATXN1,SH3BP2,FUZ,AMBRA1,DZIP1,BTBD7,ZNF667,TBL1X,SLC44A1,R3HDM1,LMF1,ZNF32,ZNF74,REEP1,MAP3K12" Drug 6842_UP Iopromide [73334-07-3]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "DPF1,NDRG2,LTBP4,AMH,ATP2B2,SLC2A11,CFAP410,CACNA1A,TBRG4,CLCN4,AKAP7,NECTIN3,PLCH2,EDRF1,RUSC2,RABGAP1L,CDON,EFNB3,EGFR,ELAVL3,KIAA1109,FGF13,FHL1,FOXG1,GABRA2,ZNF44,GRM8,BTN2A1,KCND3,KCNJ9,AFF1,MMP16,NEK1,NEUROD1,NUMA1,GRAMD1C,PTHLH,RAD52,ASIC4,ITSN1,SNCA,IZUMO4,MAPK8IP3,CRTC1,SLC44A1,ICAM5,FLRT2,LAT2,SLC30A3,EVI5" Drug 2475_UP Benperidol [2062-84-2]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "RALGAPA1,PLA2G6,PKP4,BCAS1,ATP1A3,MYOM1,CDK5R1,CFAP410,SLC16A4,CDH2,CDO1,CLGN,B4GALT6,TAOK2,ZFYVE9,CLCN4,STOML1,SULT4A1,HOMER3,ABCG1,DCAF4,ARHGAP24,HEYL,OPTN,EFNA2,MBNL2,RASGRP2,CAMSAP1,AGAP2,FLNC,ATF7,IL6ST,NPR2,PBX1,CCSER2,GDPD2,WDR25,CCDC40,FOXRED2,PKNOX2,SNAP25,PEG10,MAPK8IP3,SYT5,PSD3,TMOD1,TRPC3,VSNL1,KCNAB1,SSPN" Drug 5796_DN Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AK2,APP,DNAH17,CDK5R1,SCAPER,SOCS6,CREM,PDE4DIP,DCAF4,GPRASP1,RIMS3,RUSC2,C2CD2L,KLHL3,KBTBD11,HIPK3,EGFR,FGFR1,BAIAP2,ERAP1,SEPT9,GPR19,CNTRL,SYNPO,ICA1,TJAP1,MAPT,ZNF862,PAK3,PBX1,PFKFB2,CDIP1,MINDY2,RAD51D,RAD52,FBXW7,CSRNP3,IL17RB,AMBRA1,KDM4C,SPTAN1,SAMSN1,SYN2,SYT1,MCF2L,TIAM1,TK2,TPM2,UGT8,ST7" Drug 576_UP "novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "PLA2G6,AMPD3,ANK1,APAF1,APOC1,PRX,ARSF,ADAM23,C5,KALRN,HAP1,KCNAB3,CDH18,DLGAP1,CHN2,PICK1,OSBPL3,DCC,DMD,EFNB3,ETV1,PTK2B,KIAA1109,NSG1,DISC1,NR3C1,GUCY1A1,KCNJ5,SAMD14,NCF2,NTRK3,OPRL1,SNTG1,PDE1C,CDK14,PLCD1,LRRN3,C1orf54,BEND5,RNASE1,SYNDIG1,RXRG,SNCA,ZCCHC24,SPART,GANAB,PHF24,SEZ6L,CLIP2,SLC17A7" Drug 5004_UP Luteolin [491-70-3]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "DPF1,SYN3,MRTFA,TRMT9B,APOC1,RGS20,ALDH4A1,ALDH7A1,ADAM23,BAIAP3,NEURL1,CACNA2D2,NRG2,CTIF,SRGAP3,TMCC2,DTNA,EGR3,CDKL3,DLC1,ZNF589,FGFR3,GABRA2,GLS,GSN,FICD,KCNH2,MGAT3,CD200,ZNF862,NF1,NNAT,KCNK10,SERPINI1,EPN1,PACSIN1,LRRN3,PPP5C,TTC13,RGS10,MYH14,KANSL3,COA1,ATP10B,SYN2,SEMA4A,WSCD1,SLC35G2,SEMA3B,TIGD6" Drug 7019_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "CDC42BPA,PKP4,APBB2,APOC1,PPFIA3,APP,CDC14B,ARRB2,EIF4G3,MTMR9,CDK5R1,LHX2,PLAA,MAP4K4,HOMER3,CDC42BPB,PUM1,ZNF337,GIT2,DNAJC6,PARD6A,SUGP2,BAIAP2,EFCAB2,GRB10,RNFT2,HSF2,KIF5C,NF1,OPA1,PC,SLC25A23,SMIM7,PPP3CC,PRKACB,ARHGEF10L,EPN2,DOP1A,WDTC1,SOX3,ANKRD12,TCF7L2,BHLHB9,TRPC1,CADM1,NSD2,TFIP11,MAP3K12,GDPD5,GAN" Drug 1311_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG3,PPFIA1,GAS7,CDK13,STX16,N4BP2L1,CANX,SPAG9,FOXN3,NIPBL,ARMC8,RNF14,TBC1D5,DBN1,DBT,RCAN1,FAM13A,LPAR6,FCGRT,HTATSF1,EML4,MAP4K5,HSF2,ICA1,INPP5B,MBNL1,NF1,MINDY2,SAMD9,SIDT1,PTK2,RET,ELMO2,SON,TAB2,SS18,NXT2,NCDN,FAM168A,SYPL1,FBXW11,TLR4,TPD52,TPM4,ELP5,UBE2H,LAT2,CLDND1,ZNF45,MPPE1" Drug 5785_DN Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADCY6,MTUS1,BIN1,AMT,ASPH,CHN2,HAPLN1,CSF1,CSF1R,PHF14,ARHGEF4,PPP6R2,DCAF4,SPOCK3,DPH1,HIPK3,ELAVL2,DENND4A,ERAP1,PCDH17,SHISAL1,KIF2A,MATN3,NDUFA5,NF1,NPR2,PBX1,NLE1,MAPK7,RIPOR1,SH3TC2,RGS10,ZNF671,ATXN2,SCG5,FBXO11,ANKRD6,PEX26,COBL,MCF2L,SZT2,ARHGEF12,AHCYL2,CHST8,PARD3,TNS1,HIRA,CADM1,LMF1,WIPF1" Drug 2322_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADORA1,ADRA1D,CDC42BPA,APC,APLP1,ASPH,ASTN1,CADM3,N4BP2L1,GYG2,LHX2,ZFYVE9,SULT4A1,AKAP6,PHF14,CYBB,ARHGAP24,SPOCK2,JAKMIP2,CNIH3,HIPK3,FGFR1,CSPG5,FUT9,ALDH1L1,NR3C1,ATXN2L,LIFR,ADAM22,SLCO1C1,NPTX2,SERPINE2,PNMA3,MAPK8,PTHLH,ZDHHC14,ZFHX4,SALL1,STUM,SHANK2,COA1,SPP1,SLC19A3,TMOD1,TNS1,VIPR2,CLIP2,LAT2,PLSCR4,ST7" Drug 6494_DN Proxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ANK3,APBB2,KIF1A,BCL2L2,MAP7,KRIT1,AP4M1,CDH8,RAB28,AKAP7,FEZ1,FAM169A,SDC3,EDRF1,DCAF8,DAPK3,DBT,JAKMIP2,ZNF804A,SMG7,MED12,ABI1,SIDT2,COQ7,FECH,TRMO,GART,GPR37,GRIK5,MAP4K5,ICA1,KCNJ3,MBNL1,MEIS1,LYRM9,TMEM104,ZNF331,FBXO11,SLC20A2,SPART,CLASP2,ASTN2,BEX4,TPM1,CLDND1,ZFAND5,SYNC,C12orf4,RNF170,RNF146" Drug 3069_UP Butylparaben [94-26-8]; Up 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ABAT,ARID1A,ADGRF5,BCAR3,ALK,AMPH,APBB2,PLA2G4C,PDE8B,CADM3,ARHGEF1,CHN2,ABCG1,EDRF1,KIAA0513,DCT,ECM2,FCF1,IRAK4,ELAVL3,LRRC23,STX2,DLC1,BAIAP2,FHL1,SORBS1,C1QL1,HPGDS,POLL,IL1RAPL1,HRH3,HNMT,MAP4,GIT1,MX1,NAP1L2,NNAT,DUSP26,CCSER2,CNNM2,RAD52,FAM102A,ST5,ARHGEF12,TNS2,TK2,TMPO,TPD52,UGT8,SLC30A3" Drug 2291_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "SEMA6A,APC,MARK4,PROM1,KSR1,CAMK2B,CBFA2T2,ARHGAP33,GPR37L1,CHGB,DNAJB5,WHRN,TCEAL2,CRMP1,CTIF,DMPK,ZNF589,FAM49B,DLL3,GABRA2,GAD2,GAP43,ATP8A2,NEU3,CYP46A1,MALT1,NR3C1,GRM7,TJAP1,MATN3,MN1,MYH6,NDUFA5,NEFM,OLR1,PFKFB2,EPN1,VPS13C,ENOX1,EMID1,DOCK10,SP4,ATP10B,SYT5,ZEB1,HIF3A,TEX15,TIMP4,OSBP2,KAT6A" Drug 2253_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NME5,MARK4,BRINP2,AZGP1,PROM1,LDLRAD4,SLC16A4,TPP1,STOML1,WHRN,SLC12A6,DPP6,HIPK3,ING4,DLC1,SCARA3,PDLIM5,GABRA5,RND1,GLS,NR3C1,GRM2,KCNC1,KCND3,KCNK2,LMO1,VWA5A,MID1,NPPA,PDE2A,ENPP2,TMOD2,PGAM2,PIK3CD,NECAB2,PTPRB,RAD52,RFX2,FNDC3A,SOX2,MAPK8IP3,ARC,ANKRD12,EXOC7,DMXL2,TRPC1,TUB,WIPF1,SCG2,PLSCR4" Drug 6063_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,C1QTNF3,CDC14B,ATM,CFLAR,ST3GAL5,BTRC,ARHGEF2,HOMER3,CRY2,CSF1,FEZ1,PDE4DIP,DZIP3,GPRASP1,RIMS3,SMG7,DTNA,HIPK3,FCF1,EFNA3,EGFR,ING4,FECH,GALC,MALT1,GLYR1,GLS,GRIK5,IL6ST,KIF5C,ADAM22,NF1,NLE1,MBOAT7,PRKAB2,ZDHHC14,FBXW7,PPP1R9A,KIF16B,FBXO11,TTBK2,ARHGEF9,KAZN,IQCE,TRIM2,AP4E1,ZNF34,KCNK12,PHTF2" Drug 2541_UP Propidium iodide [25535-16-4]; Up 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "APAF1,NCOA1,SYNJ1,PTBP2,CHN1,EPS15L1,CLCN4,NMT2,HAPLN1,SLITRK5,GSDME,SIDT2,EFNB3,FAM13A,MBNL2,ING4,COQ7,REEP2,OLFM1,FHL1,SORBS1,FYB1,GAB1,GFER,RND1,CRCP,GUCY1A1,WIF1,ATXN2L,KCNN1,NOS1,PCDH9,PFKFB2,PFKFB4,CCSER2,PPP5C,RIPOR1,FBXW7,SYNDIG1,ZNF821,ITSN1,PEX26,TMCC1,DOK5,MAPK8IP3,PSD3,AHCYL2,ZBTB38,EMSY,STMN4" Drug 168_DN sulindac; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "CDK10,BCL7A,CFLAR,WASF1,MYRF,CFAP410,HIP1R,UBE2L6,CHRNB2,TAOK2,NCOR1,NCOR2,CSNK1E,SGK2,YAF2,COQ7,LRRC23,ZNF589,FGFR3,SEC23B,TRMO,GAP43,GRIK5,FAM107A,ATXN2L,MYT1,NAP1L1,SETD4,OMG,MBOAT7,PPP2R3C,RASGRF1,RLBP1,FOXRED2,MAPK12,ZNF821,SH3BP2,ITSN1,LIMS2,KDM4B,GLT8D1,MAPK8IP3,STX1A,KAZN,PCDHGA1,TK2,CBX5,KAT6B,CHST5,SLC13A3" Drug 4669_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "APBB1,APC,GAS7,ASCL1,ATP1A2,ALDH7A1,B3GALT2,ATP6V0A1,ADGRB3,RGS11,RGS9,CACNA1D,HOMER3,CSF1R,SEC14L5,AK5,CHRDL1,TOM1,RASGRP2,DKK3,LYVE1,RUNDC3A,GRM7,KLF12,HTR2A,IGF1,IL6ST,KCNMA1,ADAM11,AFDN,NEFM,OLR1,PDGFRA,PENK,PPARA,PKN2,ELOVL2,CCDC40,RAD52,ENOX1,SH3BP2,ST8SIA1,OGDHL,KIF13A,ZNF34,ZMYND8,LAT2,EPM2A,CAMK1G,SENP7" Drug 5776_UP Hexestrol [84-16-2]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,LTBP4,BEGAIN,EPB41L5,CADM3,KIF1A,ADAM23,RGS11,NRP2,ST3GAL5,BAIAP3,CACNB2,INA,DLGAP1,CHGA,WHRN,COL9A2,CRY2,CSNK1E,RIPOR2,ELAVL3,PDLIM5,ALDH1L1,PRUNE2,GRK4,GRIA4,ADAMTS13,PADI2,ICA1,ITIH2,KCNB1,MYL3,OPCML,RETREG1,TNPO2,POU6F1,RASGRF1,KCTD17,MYH14,STUM,HKDC1,SLCO1A2,SNCA,SPTB,ARC,DOCK9,CA14,AMOT,WIPF1,MAP3K12" Drug 1017_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "APP,MARK4,SCAPER,GYG2,SRSF11,B4GALT6,CLCN3,ABCG1,PPP6R2,EDRF1,DBT,PARD6A,DTNA,KAT8,NOP56,EFCAB2,CGREF1,CSPG5,INPP5K,TXNL4A,HTATSF1,GPR37,FICD,DHX35,KCNJ3,MAP4,MMP16,GIT1,SLC11A2,PCDH9,PDE3B,PLXNB1,LRP12,POLG,PPP5C,PRKAR1B,LRRC49,FOXRED2,PEX26,SPTAN1,NXT2,SEPT8,ARHGEF9,SYT1,EXOC7,KIAA0930,HIRA,UBTF,SMIM8,PHTF2" Drug 5816_UP Ungerine nitrate; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MTUS1,BEGAIN,AMH,AMPD3,ST3GAL5,LDLRAD4,BTRC,CA12,KYAT1,SYNGR3,CNOT8,ABCG2,IQCK,CSF1R,CTH,TM9SF4,OPTN,EGFR,FGFR1,HPCAL4,C1orf61,SEMA4D,PDLIM5,GABRA2,ERAP1,SYT17,GPM6B,CACFD1,GRM1,SYNPO,KHK,KIF5C,AFDN,MMP16,TAGLN3,NOVA2,PPP5C,FAM184A,ASAP3,ARHGEF40,SMARCA4,TMCC1,DDN,CEP68,ASTN2,IQCE,PCDHGB6,PCDHA5,RIMBP2,WIPF1" Drug 5974_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ACTN2,AP2A2,ALK,APBA2,APBB2,PPP4R4,CADM3,CACNA1D,CDH18,ARHGEF6,NCOR2,DTNA,ELAVL2,ELAVL3,CDKL3,FABP7,CACNG3,C1orf61,PRELID3A,GAB1,GAD1,ALDH1L1,GFAP,GLS,GRIK5,PTGDR2,IFI16,INPP5B,KCND3,NOVA1,PCBP3,NUMA1,PFKFB2,POU3F2,KCTD17,SYNDIG1,ASIC4,BCAN,SLC9A5,KDM4B,ZCCHC24,KDM4C,ZNF423,MAPK8IP3,PHLDB1,CLIP2,LAMP5,UPF3A,ITM2C,KAT6A" Drug 5732_UP Sulfameter [651-06-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "SYN3,NR0B1,TRMT9B,CDC42BPA,BACH1,ADGRB2,BMP7,ST3GAL5,CACNA1I,CA12,RUNX1T1,CDO1,IFFO1,CREM,NCOR2,RGS6,ABCC9,PLXNC1,OLFM1,HPCAL4,COPS8,GPM6A,ADAMTS13,GRIN1,KCNA1,KCNMA1,NEFH,NF1,PCSK1,PDE4D,PPP5C,PTAFR,ACSS3,C1orf54,PRR5L,PKNOX2,MYO16,TSNAXIP1,ZSWIM8,SPP1,POGZ,VAMP1,HIF3A,TEX15,THBS4,ICAM5,TMOD1,PIK3R5,ZMYND8,RPRM" Drug 2110_UP Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARID1A,LTBP4,APC,GAS7,APP,CFLAR,CACNA1I,NEURL1,DNAJB5,PDE4DIP,DCAF4,MAML1,EDIL3,FCF1,EGFR,LPAR6,PLEKHO1,ANKMY1,KIAA1109,FOXG1,C1orf61,SYT17,SPIN1,POLL,TDRKH,GPER1,INPP5B,JAK2,MDFI,MYO7A,PBX1,PDGFRA,RC3H2,POLG,GAL3ST4,RGS4,TTLL7,FNDC3A,TMCC1,TSNAXIP1,CLASP2,NXT2,PRRC2C,TCF4,TCF7L2,WASHC4,TIAM1,TK2,RBFOX2,SENP7" Drug 3933_DN Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG2,BIN1,SEMA4G,PLA2G4C,MARK4,ASPH,ATM,ALDH7A1,CDK5R1,HAP1,KRIT1,PLAA,CPS1,DRD1,DTNA,HIPK3,EGFR,ERBB2,CDKL3,CAMSAP1,PRELID3A,PCLO,IGSF1,KCNMA1,VWA5A,MBD1,MDM4,BCO1,NDUFA5,PFKFB2,RETREG1,PLCD1,PTHLH,RAB3IL1,CPEB3,DOCK10,SMTN,SOX2,EMC1,IQSEC2,ATP10B,THSD1,MAPK8IP3,PLCB1,SYN2,COBL,ARHGEF12,EMSY,EVI5,KCNAB1" Drug 3230_DN Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,ADRA1D,PLA2G6,BIN1,CDC42BPA,DGKD,FAM131A,ARRB1,RGS20,MARCH3,CFLAR,CDK5R1,SYNJ2,SPAG9,USP2,CRLF1,SOCS6,LHX2,EPS15L1,SLC4A7,CREM,PDE4DIP,CTNND2,CDON,TOM1,EDNRA,CNNM1,EFNA3,HSD17B14,MTSS1L,SEMA4D,KCNQ3,MGAT3,MITF,MAPK7,RAB3IL1,ATG16L1,EMID1,NLGN1,WDTC1,TSPYL2,NCDN,VAMP1,PIK3R5,ZKSCAN5,PLPPR2,VIPR2,REEP1,TIGD6,GAN" Drug 1401_UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "PPFIA1,APP,SHTN1,EIF4G3,N4BP2L1,CA12,CNOT8,AKAP7,SLC4A7,CRYM,ZEB2,SORBS3,EPB41L2,VPS26C,SEC23B,STAG2,ZMYND11,GLS,PCSK1N,MAP4K5,KCNN2,LAMP2,MAP4,NAP1L1,PDE3B,PLCD1,RETREG2,PPM1B,PRKACB,RPRD1A,CLIP1,ATXN7,CHD9,KBTBD4,MAPKBP1,FNBP1,SPART,TROVE2,ITPRID2,EPB41L3,ST5,STAU1,SEPT8,KLHL7,VPS13A,SIRT1,WIPF1,XRCC4,EVI5,CAMK1G" Drug 4198_UP Trichlormethiazide [133-67-5]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "BIN1,GAS7,PPP4R4,ZSCAN18,BCHE,NRP2,SCAPER,SCARB1,SYNGR3,ARHGAP33,MAGI1,ASIC3,CHRNB2,AKAP5,DTNA,EDIL3,HIPK3,FRY,EFNA3,PLEKHO1,CORO2B,ZNF589,OLFM1,CAMSAP1,CSPG5,HBS1L,DISC1,ATP8A2,KLF12,ITPKA,SMAD1,ADAM22,NF1,P2RY1,NLE1,PTCH1,ZSCAN32,RFX2,PNMA8A,TCP11L1,SEMA6D,SLC8A1,SLCO1A2,NPAS3,THSD1,TAC3,PCDHA5,AMOT,FLRT2,WIPF1" Drug 1526_DN Midecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,ARID1A,APBB2,APOC1,SLC4A4,BTRC,KYAT1,CBFA2T2,CRLF1,SULT4A1,SLC4A7,ABCG1,CSNK1E,DZIP3,SDC3,EDRF1,SMG7,TMCC2,DNM2,EGFR,MBNL2,ANKMY1,EZH1,NOP56,GLYR1,SLC2A6,KCNH2,MAP4,NF1,NFYA,PDE3B,CCSER2,MAPK8,TCP11L1,ZNF821,BTBD7,ZKSCAN3,MAPK8IP3,PLCB1,ARC,ATP11A,FBXW11,KIAA0930,TNS2,AP4E1,RPRM,UBTF,VGF,ZNF23,PHTF2" Drug 1541_DN Chlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADD1,CDC42BPA,EPB41L5,GAS7,ARRB1,SLC4A4,CFLAR,ST3GAL5,BTRC,CBFA2T2,UBE2L6,CLCN3,SULT4A1,DCAF8,LYPD1,SMG7,TMCC2,TOM1,MBNL2,DENND4A,ZNF589,FAM49B,OGA,AHDC1,IPO5,MIA2,NF1,CNOT4,RETREG1,NLE1,PRKAR1B,TCP11L1,ZNF821,SLC1A7,EPN2,BTBD7,KDM4B,ELOVL4,PRRC2C,PLCB1,ARC,SEMA4A,PSD3,CRTC1,TMOD1,TPM1,TRIO,VGF,UPF3A,MPPE1" Drug 2772_DN (-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "PLA2G6,C1QTNF3,CDC42BPA,ARRB1,BMP7,SCAPER,CACNB2,ARHGEF2,CACNA2D2,SOCS6,PLEKHB1,DNAJB5,SIPA1L1,PDE4DIP,KIAA0586,JAKMIP2,PARD6A,EZH1,ZNF589,FGFR1,FOXG1,HBS1L,ALDH1L1,GLYR1,GLS,GNG4,NR3C1,ITIH2,KCNN1,VWA5A,LSS,MITF,NPTX2,LRP12,RAB3A,PAQR6,KIF16B,SLC6A8,KIF13A,WDTC1,ARHGAP26,CEP68,PCDHA6,TMEM121,THRA,TK2,CABIN1,REEP1,DNALI1,GDPD5" Drug 7482_UP Acetohexamide [968-81-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AP2A2,SEMA6A,LTBP4,MRTFA,AMPD3,SEMA4G,KIF1A,ARHGEF2,DNAJB5,CSF1R,SDC3,DBN1,CELSR3,ING4,KIAA1109,CAMSAP1,TPK1,GPR153,SRCAP,RAB30,ADAMTS13,NR3C1,TJAP1,MAP4,MDM4,MPP2,ADAM22,LYRM9,NOVA2,MTRF1L,LRRN3,WDR25,MYH14,SEC14L1,ZNF821,SHANK2,LIMCH1,MAPKBP1,SNCA,USP33,WDTC1,HECW1,ELOVL4,TCF7L2,TRIO,CLIP2,ZNF45,SEMA3B,MVB12B,NUP214" Drug 4823_DN Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AK2,APLP1,DGKD,CDK10,CFLAR,ARHGEF7,CCNT1,SYNGR3,CTNND2,MFAP3L,MTSS1L,NCALD,ANKMY1,ZNF589,ERAP1,DISC1,GNG4,STON1,GPER1,RNFT2,MAP4K5,ELOVL5,HNMT,INPP5B,IPO5,LYRM9,NF1,NFYA,OGG1,SLC25A23,TMEM231,RAB3A,RAB3IL1,RGS10,RGS12,SH3BP2,FBXO11,SLC22A4,SON,SOX2,ZCCHC24,ARHGAP26,ARHGEF9,VPS13A,KAZN,SZT2,CRTC1,TK2,ZNF45,SSPN" Drug 6819_DN Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "RALGAPA1,ADCY6,ALCAM,CDK10,ARHGDIG,ATM,ATP6V0A1,CFLAR,BMP7,GYG2,CACNB2,SCARB1,TAOK2,PLAA,NCOR1,CSNK1E,RIMS2,DBN1,DCTN1,ACOT8,DTNA,PHC2,FER,ANKFY1,OGA,POLL,CNTRL,CACFD1,IGSF1,INPP5B,MAP4,KITLG,PCDH9,RETREG1,PPP5C,NKAIN1,RGS10,ZCCHC24,PHLDB1,SYT1,IQCE,TCF7,ZNF34,VAV2,NDRG4,WNK1,MPPE1,C12orf4,EPM2A,ST7" Drug 2204_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADRA1D,AP2A2,C1QTNF3,ALK,PPFIA4,APOC1,MPDZ,SYNJ2,LDLRAD4,LARGE1,CDO1,AKAP7,SEC14L5,DBT,DTNA,E2F5,FAM13A,LRRC23,KCNMB2,STX2,ERCC2,RRAGB,KAT8,MYT1,NCAM1,PLCD1,PLP1,PTPA,PPP5C,CEP41,PRKCZ,PTAFR,PTPRO,RAB3A,TCP11L1,FNDC3A,LIMS2,DOP1A,IZUMO4,CAND2,SPTAN1,TSPYL2,JMJD6,ZMAT3,TGFBR3,PARD3,TPM3,ZKSCAN5,VSNL1,EVI5" Drug 4968_UP Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADORA3,NME5,ASPH,CDK5R1,SCAPER,LDLRAD4,CBFA2T2,CLGN,SOCS6,ARHGEF6,ARMC8,CPS1,CTH,DCAF8,RUSC2,ATN1,EGR3,ING4,DMTN,CACNG2,SEMA4D,GPR153,GAP43,GNAO1,GPM6B,STON1,KCNH2,KCNQ3,KPNA5,VWA5A,LSS,TM6SF1,ADAM22,ZNF862,MTRF1L,MINDY2,PTPRO,ZNF493,RGS12,KCTD17,TCP11L1,CPEB3,ZNF423,RGL1,SYN2,ZEB1,HIRA,VAV2,LAT2,SSPN" Drug 7138_DN Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AK2,MADD,NCOA1,PTBP2,SLC4A7,CDC42BPB,DCAF4,ARHGAP32,GIT2,DBN1,C2CD2L,RHOBTB1,PARD6A,DLG3,FEM1B,SUGP2,ELAVL2,EPB41L1,RACK1,FGFR1,TACC2,PDLIM5,CAMKK2,CELF1,FERMT2,SLC2A6,ARHGAP19,IL6ST,DIPK1A,NF1,NOVA1,PIK3CD,PIK3R1,POLG,RIPOR1,RAB3A,ROGDI,SUGCT,WLS,ATXN7,EPN2,CAMTA2,RGL1,VPS13A,EXOC7,SATB2,TCF7L2,TK2,TRPC1,SSBP2" Drug 6568_UP PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADCY6,AP2A2,CASK,ATM,MPDZ,SLC4A7,HAPLN1,PDE4DIP,CNTNAP2,PHF14,CTH,DBT,SMG7,DNM2,TUBD1,GPHN,F8,EFEMP1,ZNF274,WASF3,ZNF276,GLRB,GOLGB1,GPM6B,KCNK1,KPNA5,MAP4,MIA2,PDGFRA,PLEC,MAPK7,GRAMD1C,TMEM231,KIRREL1,CLIP1,AP1AR,SBF1,CSRNP3,SUPT20H,KIF16B,DOCK10,TMCC1,KDM4C,SRPK2,CRTC1,RBFOX2,TSC2,CADM1,NSD2,PHTF2" Drug 3376_UP Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADORA2A,ADRA1D,TRMT9B,CDC42BPA,FGF17,SULT4A1,CSF1R,SDC3,GSDME,SRGAP3,EFNB3,MBNL2,TNK2,LRRC17,CDHR1,CEND1,KIAA1109,GRIK5,NR3C1,NXPH3,ITGA7,LMO2,MBP,MYCN,NEK1,NELL2,NF1,NPPA,PENK,PFKFB4,CCDC40,LIMS2,SNCA,HECW1,SPTB,CLSTN2,MAPK8IP3,SYT5,WSCD1,ZEB1,SZT2,CRTC1,CHST5,FLRT2,VLDLR,SPHK2,SLC30A3,NT5M,ADAMTS9,CAMK1G" Drug 3309_DN Ceforanide [60925-61-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AP2A2,SRPX,APOC1,ARHGDIG,MARK4,ASPH,ALDH4A1,SCAPER,CA4,CAMK2G,ARHGEF2,MAML1,DAPK3,MFAP3L,MBNL2,SORBS3,DMTN,CDKL3,SCML2,KIAA1109,SEMA4D,ERAP1,DISC1,SPACA9,NR3C1,ITPKB,LSS,MAN2A2,GIT1,PTHLH,RAB3IL1,ATG16L1,ZNF821,SLC6A8,SHANK2,SLC20A2,SLN,LIMCH1,ZHX3,EMC1,SPART,CLSTN2,ATP11A,SEMA4A,IQCE,TRIM2,TNS2,TK2,SEMA3B,SSPN" Drug 1809_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADD1,BRAP,APBB1,KCNAB2,APOC1,PPFIA3,MARK4,MAP7,CLU,HOMER3,SLC4A7,CSF1,RUSC2,SCML2,SCARA3,PDLIM5,SYT17,DISC1,INPP5K,SRCAP,USP19,TXNL4A,SLC2A6,DHX35,SHISAL1,KIF2A,KIFC3,MPP2,GIT1,MX1,OGG1,PFKFB2,KCTD15,PMS2,PTPA,RAB3A,MYH14,MAPK12,FAM214B,SS18,MAPK8IP3,EXOC7,IQCE,WSCD1,AHCYL2,BHLHB9,LMF1,ZNF32,WIPF2,SMIM8" Drug 5429_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "C1QTNF3,ALCAM,BCAS1,ARHGDIG,CCNT1,ARHGAP33,MAGI1,TPP1,NMT2,QKI,ARHGEF6,CTH,EDRF1,NOS1AP,SMG7,RABGAP1L,DTNA,EFNA3,AHDC1,GLYR1,GPM6B,GPER1,GRIK5,ATXN2L,IL6ST,IPO5,LSS,KITLG,ZNF862,NF1,CNOT4,NLE1,LRP12,CNNM2,EMID1,ASAP3,EPN2,SLN,LHPP,PLCB1,IQCE,RPGRIP1L,CRTC1,TGFBR3,CADM1,VIPR2,EVI5,SEMA3B,EPM2A,ST7" Drug 6361_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "DOC2A,AMT,SEMA7A,CDC14B,PPP4R4,ARRB2,CFLAR,BMP7,BAIAP3,CACNB2,INA,ZMYM4,ABCG2,WHRN,AATK,SLITRK5,CTNND2,ARHGAP24,ATN1,SIDT2,EFNA3,EFNB3,FAM13A,PLEKHO1,FGF1,SCARA3,FYB1,ERAP1,GPER1,RASSF8,MDFI,AFF1,NRCAM,PALM,PTPRN2,TMEM231,GAL3ST4,SCN8A,STUM,SLC20A2,SNCA,KIF13A,KDM4C,CEP68,ARC,KAZN,KIAA1107,TK2,VGF,XRCC4" Drug 6322_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,ADCY6,PLA2G6,BIN1,PDE8B,CACNA2D1,HAP1,CACNA2D2,NCOR1,ARHGEF4,HDAC9,RUSC2,KBTBD11,EDNRA,ELAVL2,ETV1,ST3GAL6,BAIAP2,AGAP2,DPYSL4,TRMO,ZMYND11,TMEM8B,NEU3,CACFD1,SYNPO,MAPT,MGAT3,ADAM22,MT1M,MX1,PFKFB2,PIK3R1,CCSER2,BCAS3,SNRK,PTCH1,PTPRE,RAB3A,RAB3IL1,TMEM206,SCN8A,NTNG1,SLC9A5,SLC20A2,CDK5RAP2,MAPK8IP3,HIRA,EVI5,MARCH8" Drug 5388_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AP2A2,APBA2,APP,MPDZ,BAIAP3,CACNA2D2,CHN2,FAM189A2,SLC4A7,CPS1,FAM169A,DGKG,RABGAP1L,DMPK,ATN1,DSCAM,EDNRA,CEND1,DLC1,FHL1,ALDH1L1,RAB30,GNAO1,ADAMTS13,RASSF8,ITGA7,KCNN1,ADAM22,MYO7A,CLDN11,TMOD2,PFKFB2,LRP12,MAPK8,PTN,PTPRE,KCNIP1,ZNF821,SLC2A5,SMARCD3,SNCA,PEG10,ZNF423,ARHGEF9,CRB1,HEY1,VIPR2,EVI5,KCNAB1,ITM2C" Drug 4336_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,CDC14B,PPP4R4,FAM189A2,IFFO1,CRY2,RGS6,CNTNAP2,NOS1AP,RIMS3,SMG7,DSCAM,TNK2,F3,ZMYND10,FGF1,OLFM1,ERAP1,GPR22,IL1RAPL1,KLF12,ICA1,KCNB1,KIF5A,KIF5C,TM6SF1,MX1,NOS1,NUMA1,PDE2A,MAPK7,GRAMD1C,CCDC40,RGS4,TMEM206,TCP11L1,ZNF821,SH3BP2,SLC1A7,SLC11A1,SP4,IQSEC2,RBM26,PLCB1,CRB1,TPM3,VGF,LAT2,XRCC4,SF1" Drug 3889_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NME5,EPB41L5,APOC1,CDK13,ASPH,ALDH4A1,ATM,STX16,ADAM15,SYNJ1,ARHGEF7,CSF1R,CTIF,MFAP3L,HP1BP3,DRD1,ATN1,FCF1,ERCC2,RRAGB,KIAA1109,FGFR1,SCARA3,IQCG,GCNT2,GLYR1,GRM8,GSN,ICA1,KCNJ3,VWA5A,LSS,NDUFA5,NF1,PIK3R1,LRP12,MAPK8,RNASEL,ASAP3,PEX26,ZKSCAN3,COA1,LHPP,PLCB1,ATP11A,EXOC7,TNS2,TMPO,MPPE1,PHTF2" Drug 885_DN 5186223; Down 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,APOC1,ALDH4A1,GYG2,CA4,KYAT1,CRLF1,TAOK2,LHX2,PARD6A,DNM1,ATN1,DMTN,CDKL3,EZH1,FHL1,FAM49B,GAB1,SYT17,RNFT2,KCNF1,NPR2,SLC11A2,NUCB1,SETD4,OXTR,PTPA,PRKAB2,PRKAR1B,MAPK8,PRPH,SAMD9,SAFB,SH3BP2,ASAP3,ZHX3,LHPP,IQCE,KIAA0930,PCDHA5,ZNF34,CABIN1,ZMYND8,HIRA,VGF,MICAL1,SF1,PCBP4,MPPE1,TIGD6" Drug 3813_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "TTYH1,SYN3,ASIC1,ADORA1,NLGN4X,BMP7,BAIAP3,CACNA1D,B4GALT6,AKAP7,AKAP5,NCOR2,ATRNL1,ARHGEF4,RIPOR2,MYEF2,TRAPPC9,SIDT2,EZH1,REEP2,FAM198B,DPYSL4,GALC,ERAP1,GLS,GRM7,KCNJ5,KIF5A,LAMA2,VWA5A,AFDN,NCAM2,NF1,NTRK2,PDZRN4,PACSIN1,PTAFR,STUM,CNKSR2,SLC1A6,SLC1A7,FAM214B,PKNOX2,MAPK8IP3,MCF2L,PCDHGA10,TMEM121,CADM1,FLRT2,SLC17A7" Drug 4679_UP Pirenperone [ 75444-65-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "APC,SPTBN4,ARRB1,ARSE,DDX3Y,ATP2B2,CFLAR,SYNJ2,DLGAP1,CHRNA4,AKAP5,RIMS2,ARNT2,DMPK,TOM1,APC2,EZH1,REEP2,TUBB4A,DLC1,ATP8A1,DPYSL4,TRAF3IP2,GAD2,ALDH1L1,GPD1,ATXN2L,ELOVL5,IL6ST,KIT,MIA2,P2RX7,TREM2,PFKFB4,MTRF1L,SPATA6,CNNM2,FAM184A,PNMA8A,SH3BP2,CNKSR2,FAM214B,SLC12A4,SYN2,PCDHGA10,SEZ6L,LAT2,KCNK12,PRDM2,KCNAB1" Drug 3202_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,AP2A2,BCAS1,ARRB2,MARK4,ATP2A2,ATP6V0A1,CFLAR,ST3GAL5,SCAPER,MTMR2,CAMK2G,FAM189A2,ARHGEF6,AKAP7,SH2B1,CRY2,ATRNL1,PPP6R2,CYBB,CTIF,RABGAP1L,EDNRA,EFNA3,SORBS3,FGFR1,BAIAP2,ZNF44,TRAF3IP2,STON1,LPAR4,NF1,NNAT,MINDY2,RELN,LRRC49,TMEM104,PTPRE,RGS12,KDM4B,TROVE2,TTBK2,TACC1,SMG6,DOCK9,AHCYL2,PARD3,CABIN1,VIPR2,REEP1" Drug 7351_UP Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ABHD6,KIDINS220,C1QTNF3,BIN1,ARHGDIG,PDE8B,AZGP1,SYNJ2,RUNX1T1,CCKBR,USP2,MTMR7,NEURL1,CHM,ARHGEF6,PICK1,BRINP1,MFAP3L,RABGAP1L,GNE,SUGP2,EZH1,FGFR1,PRELID3A,OGA,GAD1,DISC1,STON1,GRM8,KCND3,PACRG,MAP4,MGAT3,NDUFA5,NOS1,PALM,CDK18,SLC25A23,ZSCAN32,FAM184A,RGS12,TRAPPC13,FAM214B,CCDC88A,SOX3,VPS13A,ATP11A,MICAL1,SEMA3B,SSPN" Drug 7332_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,AP2A2,AK2,ALCAM,CDC42BPA,APC,APOC1,PPFIA3,CDK13,NUMB,CA12,SPAG9,ZMYM4,RAB28,NCOR1,SOCS5,DZIP3,GPRASP1,LYPD1,SIDT2,IRAK4,COQ7,F8,NOP56,GRB10,RNFT2,KCNF1,LIG4,KITLG,ZNF862,RAB3IL1,RNASEL,DCUN1D2,GSTCD,NEK11,TCP11L1,ITSN1,UHRF1BP1L,CEP68,SZT2,AHCYL2,TMEM121,TPD52,VAV1,XRCC4,REEP1,TFIP11,EMSY,MARCH8,GAN" Drug 3447_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARHGDIG,SLC4A4,SYNJ1,FOXN3,CHM,TAOK2,CHD5,PDE4DIP,SEMA3D,EGFR,ERCC2,NCALD,SEPT9,ALDH1L1,PCDH17,GNAO1,DIDO1,SPACA9,GRIK5,NR3C1,GRM1,JAK2,MAP4,NF1,NNAT,SMOX,PPP2R2B,PRKAR1B,PTHLH,ZDHHC14,SH3BP2,EPN2,FAM214B,SLC11A1,ZCCHC24,ATP10B,ZC4H2,INKA2,PHLDB1,STX1A,KAZN,WSCD1,KIAA0930,PCDHA5,TRH,VGF,MICAL1,SLC30A3,WNK1,PRDM2" Drug 6924_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG3,BRAP,APP,CDK10,ARNTL,ARRB2,SYNJ2,SPAG9,NMT2,C2CD2,PDE4DIP,DSCAM,RCAN1,CDKL3,PRKAG2,PDLIM5,INPP5K,AHDC1,HTATSF1,KCNMB4,KIF3A,TJAP1,IL6ST,KIF5C,IPO5,MAP4,NPR2,SYTL2,CCDC25,AP1AR,TRA2B,ITSN1,ABLIM3,SMTN,BTBD7,CDK5RAP2,ERC1,FBXW11,TCF7,KAT6B,RBFOX2,METTL3,TRPC1,TSC2,HIRA,UBTF,LMF1,FIP1L1,MVB12B,PHTF2" Drug 1496_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG3,FAM131A,CDK10,MARK4,BMP7,SYNJ2,MTMR3,BTRC,ZFYVE9,QKI,GIT2,SMG7,TRAPPC9,RCAN1,OPTN,EFNA3,SORBS3,EPB41L1,ANKMY1,ZNF589,KIAA1109,SEMA4D,PRELID3A,GPR153,USP19,TXNL4A,FERMT2,ITPKB,KIF5C,MEIS1,MIA2,SCAMP5,NEK1,SLC25A23,MED1,SIDT1,SUSD4,PAQR6,ABLIM3,BTBD7,ZNF423,ZBTB43,SEMA4A,MCF2L,KIAA0930,TRIM2,PARD3,SEMA3B,EPM2A,SMIM8" Drug 6700_DN Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MRTFA,BIN1,APOC1,SEMA4G,ST3GAL5,ARHGEF7,SYNGR3,RAB26,IQCK,CREM,CNTNAP2,ARHGEF4,CNIH3,RHOBTB1,SMG7,SGSM2,EZH1,AFF2,B4GALNT1,C1QL1,MSL3,GPM6B,GPR37,KCNN1,OPCML,PALM,PDE4A,FA2H,POLG,MAPK7,GRAMD1C,WDR25,C1orf54,ROM1,FBXW7,RPS6KA2,MAPK12,SEC14L1,AMBRA1,FNDC3A,TMCC1,BEX1,THSD1,MAPK8IP3,SZT2,DOCK9,TRIO,HIRA,TFIP11,KCNAB1" Drug 2889_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "CDK13,PDE8B,ATM,AZGP1,CFLAR,RHBDL1,NEURL1,ARHGAP33,CDO1,FOXN3,TOX,BRINP1,ATN1,EDNRB,ELN,EIF1,EN2,MTSS1L,FOXG1,EFCAB2,PDLIM5,GPR37,GRIK5,MMP16,MOBP,CD200,ADAM22,NUMA1,OMG,PDE4B,PDE4D,PILRA,PACSIN1,POU3F4,CEP41,RGS12,SLC1A3,SMARCD3,SOX10,IZUMO4,PEG10,SLC44A1,HEY1,DAAM2,R3HDM1,PIK3R5,TRPM2,SYNC,SLC30A3,EVI5" Drug 7301_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "PPFIA3,CDK13,CFLAR,ST3GAL5,HIP1R,CHN2,WHRN,ABI3BP,PDE4DIP,DZIP3,FAM131B,ZNF804A,LYPD1,RABGAP1L,DNM1,CDON,ACOT8,AASS,SORBS3,EML1,COQ7,F3,CINP,GRB10,NR3C1,GUCY1B1,MEF2C,SNX10,PLCD1,PTX3,TMEM231,RAB3IL1,RAD51D,SH3TC2,TMEM156,MAPK12,SBF1,COLGALT2,ST5,PHLDB1,PDLIM2,TRIM2,PSD3,FRYL,METTL3,SSBP2,FAM155A,WNT7A,XRCC4,NAV3" Drug 3931_DN Benfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG2,PLA2G6,AMPD3,FAM131A,CDC14B,DNAH17,BTRC,CHM,CPS1,SH2B1,CSF1,CDON,SUGP2,EGFR,SORBS3,EZH1,DLC1,KIAA1109,FGFR3,OGA,GAD2,DISC1,SEPT9,GPER1,GRIK5,CACFD1,GSTM5,DHX35,KCNJ5,KCNMA1,KCNN1,VWA5A,GIT1,ZNF862,NEK1,NRGN,PDE4A,RETREG1,RAB3IL1,RALGDS,NLGN1,SLC6A8,CXXC4,SOX2,EMC1,PEG10,ATP10B,PHLDB1,VPS13A,POPDC3" Drug 2492_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG3,APBB2,FAM131A,APOC1,PPP4R4,PDXK,NCOA1,ADAM23,SGCE,LDLRAD4,CACNB2,SOCS6,EPS15L1,RAB33A,CLCN4,CNTN1,AATK,EDRF1,RABGAP1L,TSPAN5,EFNB3,PIPOX,GABRA2,SEPT9,INPP5K,SRCAP,GRM1,TJAP1,ZNF862,NUMA1,OLR1,PLCD1,CNNM2,PTN,PTPRN2,MRAS,ITSN1,ANKRD6,PREX2,SLC11A1,WDTC1,TROVE2,MAPK8IP3,PDLIM2,OBSL1,THBS4,TK2,XRCC4,ZNF23,NT5M" Drug 7543_DN DNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NME5,SPARCL1,APOC1,PPFIA3,ARHGDIG,ARHGEF6,AKAP7,WHRN,SLC4A8,FBXL5,SMG7,TMCC2,PHF20L1,MBNL2,PCOLCE2,BAIAP2,SCARA3,FYN,GAB1,NCKAP1,GART,IRAK3,ATXN2L,ELOVL5,MITF,MX1,NF1,PLCD1,MTRF1L,SNRK,RNASEL,MYH14,SH3BP2,KIF16B,CCDC88A,LIMCH1,RBM34,ERC1,SPTAN1,CLSTN2,PHLDB1,PLCB1,TGFBR3,THRA,VGF,VIPR2,XRCC4,PCBP4,KAT6A,TIGD6" Drug 4802_UP Pregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADORA1,C1QTNF1,BEGAIN,APC,ARNTL,ATM,ALDH7A1,CFLAR,CACNA1I,CALB2,INA,SCARB1,ARHGEF2,SEPT7,CDH10,TPP1,AKAP7,NCOR1,GREB1,MAGI2,EFNA3,ABI2,EGR3,ELN,DMTN,ANKMY1,TUBB4A,ZNF589,FGR,FHL1,POLL,GRIK5,NR3C1,INPP5B,KCNH2,KCNN1,MAOB,MMP16,NDUFA5,NF1,EPN1,C1orf54,TCP11L1,SYBU,PKNOX2,WDTC1,EXOC7,WSCD1,CLDND1,SLC30A3" Drug 1824_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "APBB2,CDC14B,CASK,MTMR9,BCL2L2,BTRC,CA12,RCBTB2,SOCS6,ZFYVE9,CLTB,QKI,PREPL,CREM,EDRF1,SMG7,TPK1,ATP2C1,HTATSF1,GPR37,BTN2A1,KLF12,HNMT,IPO5,ZFYVE21,NLE1,TRHDE,RC3H2,FSD1,PTHLH,FAT4,RBBP6,ATXN1,SHANK2,ARHGAP26,SAMSN1,SS18,ELOVL4,CEP68,DDHD2,SIN3B,SATB2,TCF7L2,TRIM2,TNS2,TPD52,XRCC4,EVI5,PLSCR4,AAAS" Drug 2788_DN Xylazine [7361-61-7]; Down 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARID1A,ALAD,APC,APOC1,CFLAR,C5,CBR1,CDC27,ENTPD4,DNAJC6,LYPD1,SMG7,DTNA,FEM1B,EFNA3,ANKMY1,KAT8,FER,BAIAP2,GLYR1,BTN2A1,SLC2A6,ATXN2L,IL6ST,KCNH2,LIG4,ADAM22,MYO9A,NUMA1,NLE1,MBOAT7,RAD51D,ATG16L1,ZCWPW1,RGS10,FOXRED2,ITSN1,AMBRA1,ZKSCAN3,COA1,ZBTB43,MAPK8IP3,MCF2L,PSD3,PCDHA6,AHCYL2,TRIO,HPS4,EPM2A,SSPN" Drug 6673_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,ADD2,AMPD3,GAS7,SEMA4G,CFLAR,MTMR3,MYRF,SEPT7,B4GALT6,NRXN3,ARMC8,WHRN,CPS1,CREM,ABCG1,RIMS3,ARMCX2,SGK2,OPTN,PLXNC1,MTSS1L,ZNF391,CAMSAP1,SEMA4D,TRMO,DLL3,FYB1,B4GALNT1,GNAL,GNG4,VWA5A,MMP16,MPP2,ZNF426,CDIP1,PPP5C,GRAMD1C,SCN8A,ASAP3,DZIP1,ANKRD6,RPH3A,ATP11A,SMG6,DOCK9,OBSL1,VGF,TFIP11,SEMA3B" Drug 4711_DN PNU-0251126 [267429-19-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADD3,SEMA6A,DOC2A,APBB2,MARK4,C5,CBFA2T2,CTIF,BRINP1,ZNF804A,FEM1B,SORBS3,MRNIP,SCML2,ZNF589,FHL1,PDLIM5,GPR153,GFER,GLS,MSL3,GNG4,GRM8,HNMT,KCNJ3,KPNA5,MIA2,MPP2,ADAM22,NF1,RETREG1,MBOAT7,MAPK7,SAMD9,RNASEL,SH3BP2,EPN2,SMTN,KIF13A,WDTC1,SOX2,CLASP2,THSD1,VGF,VIPR2,XRCC4,DNALI1,KCNAB1,NUP214,TIGD6" Drug 3216_DN Hemicholinium bromide [312-45-8]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,AMPD2,BIN1,APLP1,FAM131A,BCAS1,PPFIA3,APP,ARHGAP5,RGS20,ASPH,CDK5R1,ST3GAL5,SYNJ2,EPS15L1,QKI,CREM,DMPK,FCF1,EFNA3,RASGRP2,MTSS1L,GABRA2,EML4,SPACA9,NR3C1,GRM8,KCNJ3,KPNA5,LIG4,MITF,MMP16,NEK1,PLTP,RAB3IL1,RAD52,GTDC1,SEC61A2,CCDC25,ZNF821,BTBD7,KDM4C,NXT2,PLCB1,ZNF34,TMPO,VIPR2,ZIC3,REEP1,SYNC" Drug 5672_DN Tyloxapol [25301-02-4]; Down 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ABHD6,SLC12A5,AP1B1,AK2,APBB2,APOC1,ARRB1,PLEKHB1,NMT2,HOMER3,COL9A2,CDC42BPB,SIPA1L1,PDE4DIP,CTH,GREB1,GIT2,SMG7,DMPK,DTNA,F3,PRELID3A,AHDC1,GLYR1,RNFT2,MAP4K5,MATK,MBD1,NF1,NUMA1,PDE3B,PRODH,PRPH,PTHLH,RALGDS,PAQR6,RXRA,MAPK12,FBXO11,EPN2,ASTN2,ATP11A,TACC1,PDLIM2,TCF7,CABIN1,VAV1,ZBTB14,NDRG4,PDSS2" Drug 2445_UP Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ACTN2,MTUS1,SYT13,CDC42BPA,ANK3,APBB2,CDC14B,PLA2G4C,DNAH17,KIF1A,FUBP1,CHGA,CSF1,DZIP3,CTNND1,RIPOR2,SPOCK3,CDON,DTNB,MAMLD1,APC2,CEND1,FOXG1,NSG1,MYOZ2,GFER,RUNDC3A,GRIA1,SOX21,GUCY1A2,KLF12,KCNJ5,KIT,AFDN,MSI1,MYO6,NPPA,OGG1,NECAB2,RFX2,RGS4,MAP6D1,FERMT1,SLC11A1,ZC3H13,ATP10B,ZBTB16,CAB39L,PLSCR4,NUP214" Drug 6161_UP Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "NDRG2,APOC1,CDC14B,BMP7,CACNA1G,CFAP410,CACNB4,MAP7,LARGE1,ZFYVE9,CREM,ING4,TUBD1,RCAN2,RASGRP2,ETV1,CEND1,F5,DLC1,C1orf61,AGAP2,ZNF44,GAD2,GRIN1,GRM1,ICA1,MAP4,ADAM22,MYO7A,NF1,NRCAM,OPCML,CAMKV,BEND5,RFX2,ZFHX4,ST6GAL1,CNKSR2,ZNF365,SLC8A1,FAIM2,HECW1,LMO3,TROVE2,ATP11A,ATP13A2,VSNL1,MKRN3,KCNAB1,PARP11" Drug 5482_UP Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MRTFA,BEGAIN,ANK1,KCNAB2,GAS7,FAM131A,ASTN1,STX16,MTMR2,BAIAP3,CACNB4,DLGAP1,TAOK2,RAB33A,SULT4A1,IFFO1,CSF1,CSF1R,GPRASP1,JAKMIP2,EIF4G2,EFS,OLFM1,AGAP2,RASL10A,GAP43,SRCAP,CNTRL,MAN2A2,GIT1,NFYA,LRP12,RALGDS,SH3BP2,ARHGEF40,BTBD7,ZKSCAN3,COA1,RIMS1,SOX11,PEG10,ZC3H13,RBM26,EXOC7,PCDHGB6,VAV2,NSD2,WNK1,EVI5,SCG2" Drug 7228_UP Praziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASIC1,ADORA2A,AP2A2,AK2,ALK,SEMA7A,ATM,N4BP2L1,BAIAP3,HAP1,CDH10,STOML1,SLC4A8,GIT2,SPOCK3,DRD1,DUSP9,HSD17B14,OGA,FYB1,DISC1,NEU3,GLS,SPACA9,KLF12,IRF8,ITIH2,TM6SF1,AFDN,TAGLN3,PDE3B,GPR85,PRKAR1B,ZSCAN32,RALGDS,RGS10,EMID1,PKNOX2,ZCCHC24,PHLDB1,PLCB1,SYT5,ANKRD12,PIK3R5,TRPC1,ZKSCAN5,PRDM2,SLC17A7,ST7,SSPN" Drug 6705_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ASPHD1,C1QTNF3,AMT,ANK1,PPP4R4,ARHGDIG,ASCL1,PTCH2,RUNX1T1,ARHGAP33,IFFO1,CRMP1,HAPLN1,FEZ1,ATN1,DSCAM,DTNB,DYRK1A,HIPK3,NRN1,NSG1,GAD2,RUNDC3A,GPD1,STMN2,GRIA1,GRIK2,SPACA9,GRIK5,GRM1,HPCA,KCNC1,DDX25,MX1,CNOT4,RAB3IL1,RPS6KA2,ZNF821,ZFP30,DZIP1,ARHGEF40,KIF13A,ACSBG1,MCF2L,PCDHGA10,PCDHGA1,PCDHA5,VLDLR,KCNK12,REEP1" Drug 6095_DN Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADCY6,NME5,C1QTNF3,ALCAM,BIN1,CDC42BPA,BCAS1,CADM3,HAP1,CAMK2B,CBFA2T2,PLEKHB1,AKAP7,RCHY1,CREM,PDE4DIP,GIT2,JAKMIP2,SIDT2,SEMA4D,CGREF1,GAB1,SEPT9,ALDH1L1,GNAS,KCNMA1,IPO5,LIG4,MAP4,MATK,MID1,ADAM22,PDE4B,PLXNB1,PRKAR1B,PRPH,CNNM2,PTN,RAB3IL1,RAD52,SEMA6D,SNCA,ZCCHC24,KDM4C,MAPK8IP3,EXOC7,PCDHA6,ZNF711,HPS4,SENP7" Drug 4587_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MTUS1,BBOX1,MRTFA,TRMT9B,APAF1,APBB1,ATP2B2,CACNA1I,BSN,BTRC,HAP1,CAMK2B,SLC16A4,CREB5,VCAN,DTNA,DTNB,EDN1,ERGIC3,NSG1,SRCAP,GNAO1,PTGDR2,DIPK1A,ITGA7,KCNJ3,LIG4,LMO2,MX1,NF1,PALM,PDE4D,PDGFRA,PHKG1,MINDY2,LRRN3,RGS10,KCTD17,CCDC102B,OGDHL,TROVE2,ACSBG1,ADGRL3,PHF24,PCDHA5,AP4E1,TPM3,WIPF1,EPM2A,NUP214" Drug 2318_UP Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADORA2A,SPARCL1,ALK,DOC2A,CADM3,FOXN3,TAOK2,CLTB,FADS2,AKAP7,ATRNL1,GREB1,RIMS2,DAPK1,HIPK3,EFNB3,EN2,MTSS1L,NRN1,ATP8A1,ZNF589,FGFR3,FOLR2,GPR153,ZNF44,SRCAP,GLS,HTR2A,INPP1,ITGAM,ITPKA,ADAM22,BCO1,MSR1,NCF2,NTRK2,OPCML,MAPK8,RELN,PTHLH,BCAN,SLC1A7,SLC11A1,HECW1,COLGALT2,SYT5,WSCD1,TEX15,PRMT8,SLC17A7" Drug 2196_UP Ethotoin [86-35-1]; Up 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ARID1A,SEMA6A,ALK,CDC42BPA,CADM3,AZGP1,REPS2,CDH2,TAOK2,CLCN4,SIPA1L1,ARHGEF4,RIPOR2,SV2B,SV2A,NTM,HS3ST2,ATN1,SORBS3,ELAVL3,RCAN2,PIPOX,F5,FOXG1,AGAP2,IQCG,FLT1,GABRA2,ATF7,HSD17B1,HTR2A,MEF2C,MPP2,NPPA,PFKFB2,POU3F2,KHDRBS2,S100B,SEMA6D,MYH15,SNAP25,SPTB,PLCB1,SYN2,HIF3A,TK2,TNS1,VGF,LMF1,SLC17A7" Drug 3217_DN Phenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "OSBPL1A,APBB2,APLP1,FAM131A,APP,EPS15L1,NMT2,SH2B1,C2CD2L,DNM1,CDON,EIF4G2,HSD17B14,DMTN,MTSS1L,STX2,ANKFY1,CGREF1,GABRA2,INPP5K,SRCAP,GLS,POLL,NR3C1,ATXN2L,HNMT,DHX35,KCNQ3,MAP4,GIT1,CNOT4,PCDH9,PDE4A,CCSER2,RETREG1,PLXNB1,MAPK8,RGS12,ZNF365,ARFGAP1,KDM4C,IQSEC2,PCDHA6,TIAM1,CDK20,RPRM,VGF,MAP3K12,EVI5,SEMA3B" Drug 5525_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ABHD6,MTUS1,OGT,APOC1,ARHGAP5,ALDH4A1,SOCS6,ARMC8,COL4A5,NECTIN3,AKAP12,CSNK1E,PDE4DIP,PPP6R2,GIT2,DPH1,EGFR,PLEKHO1,EPB41L1,POLR1B,FHL1,TRAF3IP2,DISC1,GART,HSD17B1,KCNF1,LMO2,MAPT,MSI1,NASP,NF1,OCRL,PDE4A,ZCWPW1,RGS12,SBF1,BCAN,NUBPL,PPP4R3A,EPN2,TROVE2,TACC1,SEMA4A,CHST8,KCTD2,TPM1,ZBTB14,FTSJ1,MVB12B,SMIM8" Drug 608_DN NU1025; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "AMPD3,CDC42BPA,AQP6,CDK10,ARNTL,ARSE,NCOA1,ADGRB1,CFLAR,RAB29,CCK,CD86,AP4M1,CDH10,ARHGEF10,PDE4DIP,CTNND2,DRP2,DSCAM,E2F5,TUBD1,COQ7,RCAN2,GNG4,BTN2A1,SMAD1,TM6SF1,MPP2,ADAM22,MYT1,NELL2,NFYA,TREM2,SNX10,ELOVL2,SUSD4,RNASEL,DCUN1D2,TCP11L1,SELL,SH3BP2,KBTBD4,SMARCA4,FAIM2,DOP1A,ATP10B,TBL1X,PHF24,ARHGEF12,ZBTB16" Drug 6216_DN Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MTUS1,OSBPL1A,SPOP,AMPD2,ARHGAP5,MPDZ,CFLAR,ARHGEF7,KRIT1,ENTPD6,NMT2,CSNK1E,SOCS5,CTNND2,ZNF337,GIT2,PARD6A,MED12,TRAPPC9,NR1D2,EPB41L1,EZH1,CAMSAP1,GAA,MAPT,MMP16,GIT1,NLE1,FSD1,PPP2R5C,PTK2,RAP1GAP,ARID4A,TCP11L1,LGR4,FAM102A,KIF16B,TMCC1,DNMBP,TCF7L2,PSD3,SIK3,TIAM1,TRIO,CADM1,DNAJC12,CLDND1,SPHK2,PCBP4,MARCH8" Drug 6772_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "SYN3,NDRG2,BIN1,MARK4,CADM3,BACH1,CA4,ARHGEF1,NEURL1,CHN2,CHRNB2,ZFYVE9,CLCN4,CNTN1,CHD5,PDE4DIP,RIMS3,RUSC2,DMPK,EDNRA,EFNB3,TNK2,C3orf18,GPR153,RUNDC3A,GNAS,NR3C1,GRM7,KCNA1,MBD1,KCNK10,PIK3CD,MINDY2,LRRN3,RELN,PTHLH,ZSCAN2,TRIM68,RGS10,TCP11L1,KCNIP1,SP4,TAL1,CRTC1,TPM3,CHST5,SLC30A3,ITM2C,EPM2A,SSPN" Drug 1677_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "ADD3,AK2,APBB2,SLC4A4,ALDH7A1,SYNJ1,SYNJ2,HAP1,CAMK2B,NEURL1,RAB28,PICK1,BAG4,KIAA0513,TBC1D5,G3BP2,RCAN1,ERCC2,F3,ERAP1,ALDH1L1,RAB30,GNG3,GNG4,GRM1,HNMT,MBP,PLEKHB2,KLHDC8A,FOXRED2,ZNF821,SUPT20H,FERMT1,PPP4R3A,EMC1,ZNF423,SPTAN1,ZBTB43,CEP68,STX1A,EXOC7,FBXW11,WSCD1,TCF7L2,AHCYL2,HEY1,ZKSCAN5,VIPR2,REEP1,GDPD5" Drug 5508_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.03E-04 1.00E+00 2.64E-03 3.01E-02 50 197 "MRTFA,TRMT9B,APBB2,GAS7,CDK10,ASPH,RUNX1T1,CDH10,CLGN,PLEKHB1,WHRN,FEZ1,SDC3,EDRF1,CYBB,DTNA,STX2,EXTL1,SCML2,ATP8A1,FGF13,FHL1,TPK1,RUNDC3A,SOX21,KCNH2,KIF5C,MAOB,MDM4,ZNF862,MYT1,NCAM1,NF1,NOVA2,STRN3,PPP5C,SAMD9,ATG16L1,TCP11L1,EMID1,SYNDIG1,SLC15A2,NPAS3,CRTC1,PCDHA6,TRPC3,FAM155A,LAT2,PRDM2,EVI5" Drug CID000107926 bretazenil Stitch 3.05E-04 1.00E+00 2.66E-03 3.03E-02 11 23 "ALDH7A1,CCKBR,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,MATK,SST,RUSC1" Drug CID000127607 griseolic acid Stitch 3.05E-04 1.00E+00 2.66E-03 3.03E-02 11 23 "PDE8B,ALDH7A1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000123195 diimine Stitch 3.05E-04 1.00E+00 2.66E-03 3.03E-02 11 23 "PHF12,NCOR1,PNMA2,MID1,PMP2,PRKCG,ROM1,SLC14A1,TAC1,PDLIM2,SMG6" Drug ctd:C025340 manganese chloride CTD 3.09E-04 1.00E+00 2.70E-03 3.07E-02 100 458 "ACHE,DSCAML1,APC,ARHGDIA,ARNTL,ATM,ATP2B2,MYOM1,BID,CA8,CD86,NOG,AKAP7,NRG2,CLOCK,NCOR2,RGS6,ARHGEF4,HEPH,DRD1,EGFR,ABI2,ENO2,PTK2B,ATP8A1,FCGR1A,PPP1R1B,OLFM1,FHL1,FLT1,CAMKK2,DACH2,SDCBP2,GABRA1,GABRG2,GAD1,ERAP1,GFAP,TNRC6A,GLUL,MCHR1,GPR34,GRIK3,GRIN1,FAM107A,ATOH8,IGF1,IL12A,ITGAM,ITGAV,ITIH2,KCNJ3,SFXN5,MAPT,MBP,NEFH,NFE2L2,NFIX,NOS1,NPPA,SLC11A2,NTRK2,ABCB1,FA2H,MAPK3,MAPK8,MAPK9,MASP1,RELN,PTX3,RET,NUDT11,GLDN,S100B,SCN7A,SGK1,SLC1A2,SLC1A3,SLC6A1,SIRT2,SLC11A1,SNCA,SCN3B,MYT1L,STOX1,VPS13A,NUDT10,TACR1,MCF2L,PCDHA6,TEK,LEFTY2,TIE1,UCHL1,VGF,ZFP41,LRP8,RTN4,AP3B2,SLC4A10" Drug CID000003377 AC1L1TJF Stitch 3.09E-04 1.00E+00 2.70E-03 3.07E-02 22 66 "ADCY2,ADCY5,ADCY6,ADCY8,NR0B1,ATP1A2,ATP2B1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNG1,CALM1,CALN1,EDN1,ZMYND10,KCNH2,PTCH1" Drug CID000105091 Fura-2AM Stitch 3.11E-04 1.00E+00 2.71E-03 3.08E-02 25 79 "AGT,PLA2G6,ATP2B1,ATP2B2,BID,CACNA1D,CACNA2D1,CACNB2,CCKBR,CD38,DCC,SACS,ACOT8,EDN1,MAG,NBL1,NRGN,PRKCB,PRKCG,RYR1,RYR3,SLC8A2,CNTN2,TRPC1,VGF" Drug CID000003104 AC1L1F6H Stitch 3.13E-04 1.00E+00 2.73E-03 3.10E-02 31 106 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,APC,ARHGDIA,CACNA1A,CACNA1B,CACNA1E,CALM1,P2RX6,ENTPD2,CHRM1,LPAR4,GRIK1,MAP4K5,P2RY13,NOS1,NPY,P2RX7,P2RY1,TAC1,P2RY12" Drug CID000003073 diisopropyl methylphosphonate Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "ACHE,BCHE,DMTF1,PC,PIK3C2A,SPP1" Drug DB01215 Estazolam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug DB01594 Cinolazepam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug ctd:D005481 Flurothyl CTD 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "CAMK2A,PLPPR4,GABRA1,GABRB1,GABRG2,SLC30A3" Drug ctd:C042957 Ro 15-4513 CTD 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA2,GABRA4,GABRB3,GABRG2,SST,SSTR2" Drug CID000194385 homoibotenic acid Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GRIA1,GRIA2,GRIA4,GRIK1,GRM1,GRM3" Drug CID000127037 "2,3-PDCA" Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "CA4,GRIA1,GRIA2,GRIA4,SLC1A2,SLC1A3" Drug ctd:C091518 "1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane" CTD 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRB1,GABRB3,GABRG2" Drug DB00801 Halazepam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug DB01588 Prazepam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug CID003035584 cis-MCG-I Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID000060754 gadodiamide Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "AIFM1,WDR20,CASP8AP2,NACA,MRAS,SLC14A1" Drug CID000159654 neferine Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "DTNB,LRRC25,MAPT,ABCB1,S100B,RGL1" Drug CID003248290 Iem 1460 Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GRIA1,GRIA2,GRIA4,GRIN2C,GRM3,SALL1" Drug DB00546 Adinazolam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug CID003086590 w 77 Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "KDM5D,NCALD,ABCB1,GSTCD,TMEM132D,VSNL1" Drug DB01559 Clotiazepam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug CID005362399 bemoradan Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "ALDH7A1,ITGAM,PDE3A,PDE3B,PDE4B,PDE4D" Drug CID000163732 AC1Q5IQA Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "ZMYND10,B3GAT1,PDCD2,TAC1,TAC3,TACR1" Drug CID005311355 SCH 51866 Stitch 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "ALDH7A1,NPPA,PDE1C,PDE2A,PDE4B,PDE4D" Drug DB01567 Fludiazepam Drug Bank 3.16E-04 1.00E+00 2.74E-03 3.12E-02 6 8 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug ctd:D000639 Amitriptyline CTD 3.26E-04 1.00E+00 2.83E-03 3.22E-02 44 168 "SERPINA3,ABAT,ACHE,ADORA1,SEMA6A,ABCD2,C1QC,IL33,CACNA2D1,NOG,CHRNB2,SLC22A6,CREM,DCAF8,HS3ST2,DRD1,GABRA1,GABRA2,GABRA4,GABRB3,GFAP,PLCD4,GRIK1,NR3C1,IL12A,KCNA4,KCNH2,KCNN2,STMN1,LSS,MMP16,NPY,PC,ABCB1,SH3GL3,NTNG1,SOX11,SSTR1,STAC2,TRH,SLC47A2,PLPP4,STMN4,CPNE4" Drug CID000161091 2-phenyl-4-quinolone Stitch 3.34E-04 1.00E+00 2.90E-03 3.30E-02 14 34 "ACHE,ALDH7A1,AIFM1,TUBD1,TUBB3,TUBB4A,FOXM1,TUBA8,TUBA1C,TUBB2B,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug 1321_UP Apigenin [520-36-5]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.35E-04 1.00E+00 2.91E-03 3.31E-02 46 178 "ABAT,AK2,PLA2G6,AMH,C5,LDLRAD4,CCNT1,CREM,CTNND1,DNAJB6,ANKRD46,FEM1B,FCF1,EGR3,CDKL3,KAT8,CELF1,HBS1L,ALDH1L1,DIDO1,FICD,LSS,MT1M,CNOT4,PDE4D,SMIM7,PROX1,PTPRE,CCDC25,PAQR6,SFPQ,SCG5,FNDC3A,KBTBD4,SLC15A2,MYH15,IZUMO4,ZBTB43,PBLD,TAC3,TF,CBX5,MKRN3,PRDM2,KCNAB1,KAT6A" Drug CID000009589 3-acetylpyridine Stitch 3.37E-04 1.00E+00 2.92E-03 3.33E-02 24 75 "CACNA1A,CALB1,CALB2,CD38,CDO1,ATN1,TPK1,GAD1,GAD2,GJB1,IGF1,CDK14,PPP2R2B,PRKCG,PRPH,ATXN1,ATXN7,ZNF423,DDN,THRA,TNR,TRH,SLC17A7,SLC17A6" Drug 2576_UP Alexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.38E-04 1.00E+00 2.92E-03 3.33E-02 47 183 "CDC42BPA,SLC16A4,CDC27,CLGN,ZFYVE9,CLCN4,AKAP7,CREM,CRY2,FEZ1,ARHGEF10,CSNK1E,PDE4DIP,DZIP3,CTH,HDAC9,RIMS3,EGR3,EIF1,ST3GAL6,CAMSAP1,CAP2,FYN,ZNF276,GPR19,GRB10,MT1M,P2RX7,ENPP2,CNTLN,RPS6KA2,TRAPPC13,ATXN7,SCG5,RAB3GAP1,TNIK,ERBIN,ARHGEF9,KIAA1107,SZT2,AHCYL2,SIRT1,TRPS1,FLRT2,FLRT1,LAT2,PRDM2" Drug 5599_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.38E-04 1.00E+00 2.92E-03 3.33E-02 47 183 "RALGAPA1,SEMA6A,APAF1,APBA2,APOC1,AQP4,N4BP2L1,FGF17,SCAPER,CACNG1,RUNX1T1,CHN2,CSF1R,EDNRA,ING4,EPHB1,CEND1,F5,OLFM1,CAMKK2,GLYR1,GLS,STON1,PCLO,GRIK5,ICA1,KCNJ5,LMO2,MAP2,LYRM9,ZNF862,CNOT4,SERPINI1,LRP12,PKN2,PTHLH,PTPRB,CARF,KANSL3,SNCA,KDM3A,CDK19,ATP10B,CEP68,RGL1,SEZ6L,UBE2H" Drug 6166_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.38E-04 1.00E+00 2.92E-03 3.33E-02 47 183 "PDE8B,SLC4A4,BTRC,FAM189A2,CREM,PDE4DIP,JAKMIP2,FAM13A,MBNL2,SPEG,KIAA1109,FGFR1,BAIAP2,CAP2,AGAP2,GPR153,OGA,RAPGEF1,GRIK5,MSR1,NF1,NINJ2,NNAT,NTRK2,NTRK3,KCNK10,PDE4B,PFKFB2,CCSER2,PMP22,MBOAT7,PRKACB,GALNT10,HSPA4L,SMTN,TNIK,ZC3H13,ATP10B,PHLDB1,PLCB1,WSCD1,TPM1,CLIP2,ZBTB38,ZBTB16,PRDM10,FAM13C" Drug 5677_UP Bisacodyl [603-50-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.38E-04 1.00E+00 2.92E-03 3.33E-02 47 183 "CLK4,AP2A2,N4BP2L1,RGS11,FHL5,CPS1,EDRF1,SEC14L5,HS3ST2,ATN1,EDN1,EFNB3,MBNL2,RASL12,WAC,FABP7,KHDRBS3,FYB1,GNAL,GPM6B,NR3C1,BTN2A1,TJAP1,INPP5B,MATN3,NEFM,CNOT4,OGG1,MTRF1L,SPATA6,PTPRN2,FAT4,RFX2,PNMA8A,ZNF821,SH3GL3,SLC1A7,SLC11A1,ATF7IP,HECW1,AJAP1,ACSBG1,PARD3,ZKSCAN5,DNALI1,SEMA3B,JPH3" Drug ctd:C015559 trimellitic anhydride CTD 3.40E-04 1.00E+00 2.92E-03 3.33E-02 354 1913 "SERPINA3,ABCF1,ASIC1,NCKAP5,NDRG2,PLEKHG5,CCDC85A,SLC12A5,CDC7,ADRA1B,MTUS1,AK2,ADGRF5,SPARCL1,ALCAM,SRPX,LTBP4,FAM135A,ALK,GPRASP2,DPP10,GPAM,CACHD1,VAT1L,LRRC4C,USP37,APP,CPNE5,LGR5,PDXK,ASPH,RASL11B,ASTN1,ATP1A2,ATP2A2,ATP2B2,BARD1,RGS9,BID,BLM,BMP7,CDK5R1,MTMR3,C1QC,SGCE,IL33,CACNA1D,THSD7A,NFS1,PRC1,CCNH,SLC16A4,AIFM1,CD38,ENTPD2,CDC25B,CDH2,DCLK1,EVI5L,MAGI1,TBRG4,CLGN,ADGRG1,NRXN1,NRXN2,FBXO7,ABCG2,CNTN1,ZNF521,NSL1,CS,SNCAIP,BOC,PHF19,CENPL,KIF26A,ACY3,INTS1,TOMM20,SCRN1,MYEF2,DDX46,POM121,SMG7,SNAP91,SRGAP3,FAM107B,DLG4,GRIN3A,DNM1,OLIG1,CASP8AP2,DSCAM,ECM2,FARSB,ABCC9,GOLT1B,SNX29,SYT15,EEF1D,EIF4G1,SORBS3,RGS17,EPB41,EPB41L1,COQ7,RCAN2,DMTN,LRRC17,EPHB1,ERBB2,DENND4A,EFS,PIPOX,RTN3,SIRPB1,NRN1,F8,ARMCX1,ABCA8,FABP7,TMEM132C,ACSL4,TUBB4A,FDFT1,PRMT5,POLR1B,FGF11,FOXF2,SYNCRIP,IQCG,FOXM1,PSD2,FOLR2,NBEA,CINP,SMC2,SPECC1,RASL10A,STAU2,ABLIM2,SDCBP2,CHL1,GALNT15,ARPP21,MTHFD2,GART,CPLX2,GATM,TUBA8,GDF1,PCDH17,GGT5,GHR,DBF4,KDM2B,FERMT2,PSRC1,PRUNE2,GPM6A,B4GALNT4,ADAP1,NUDT21,ADAMTS8,GRIN2C,CIT,GSTT2,GYG1,WIF1,RASSF8,NXPH3,HLF,ACOT7,HMGCR,AGFG1,HSP90AA1,ICA1,IDH3A,NKD1,KNDC1,SCIN,IL11RA,BRINP3,ITGAV,KCNA6,KCNJ10,KCNJ16,CREG2,KIF5A,KLRC3,IPO5,STMN1,HECTD2,ARHGAP12,LSS,MAOB,MAP6,MATN2,IL17D,MEF2C,MEIS2,SRSF12,KITLG,AFDN,SCG3,MTR,MYCN,FXYD6,NAP1L3,NASP,NFIA,NFE2L2,NINJ2,NNAT,NTRK2,ODF2,GPR88,OPHN1,CLDN11,PBX1,PRTG,PDE1A,PDE1C,ENPP2,GNG2,OLA1,PFKP,ANLN,TMEM38A,PKM,GPSM2,PLCL1,FXYD1,PMP22,PSAT1,NECAB2,TNPO2,PPP2R5C,PPP3CC,PPP5C,EPDR1,PROX1,RELN,PSMD13,SPDL1,PTN,PTPN13,PTPRD,RAB3IL1,TMEM255A,PLEKHB2,SH3TC2,FAT4,RBBP8,CRTAC1,MORC4,RGR,RGS4,LGI2,GSTCD,ELP2,MCMBP,SGSM1,LRRK2,LGR4,FAM161B,HUNK,WLS,RXRG,RYR3,FOXRED2,TNFRSF19,SFPQ,PPP1R9A,SH3GL3,DOCK10,NTNG1,SHMT2,BCAN,ABLIM3,SLA,SLC1A3,EPN2,SLC6A8,SLCO1A2,SLC22A4,SCN3B,FNBP1,COLGALT2,SAMSN1,LRRC4,KANK1,SYT11,MLC1,RHBDL3,SYN2,SYP,SYPL1,SYT1,KAZN,ROBO3,TAF6,TAL1,SMG6,WSCD1,VWC2,TRIM2,CLASP1,TNS2,TMEM121,TGFBR3,ZNF106,THBS4,FBXL16,THRA,MTMR14,TJP1,CBX5,TMPO,PARD3,TNS1,PDSS1,RUNDC3B,TRPC3,SSBP2,TUBB2A,CADM1,EIF4ENIF1,OSBP2,FAM181B,BCL2L13,MEAF6,VLDLR,VSNL1,WIPF1,NSD2,PORCN,NPDC1,ZNF23,AGMO,SLC26A10,SPIRE1,SHD,SLC38A1,RGMA,SEMA3B,NELFE,ST7,HNRNPA3,ACTR3B,ADAMTSL3,MSRB3,NHSL1,AAAS" Drug 2370_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.41E-04 1.00E+00 2.92E-03 3.33E-02 48 188 "NDRG3,MTUS1,APBB2,KIF1A,BMP7,ST3GAL5,HIP1R,RAB26,FEZ1,SLITRK5,PPP1R16B,EDRF1,DOCK4,KIAA0513,ZFYVE16,RIMS3,DNAJC6,FAM13A,CDKL3,GAP43,INPP5K,LILRA2,NXPH3,IFI16,ITGA7,KCNH2,KIF5C,VWA5A,NCAM1,SERPINI1,PMP22,ACSM5,C1orf54,ITSN1,TNIK,ZCCHC24,ZSWIM8,KIF1B,RGL1,STXBP1,ACSBG1,JMJD6,DNMBP,SYNE1,TGFBR3,SSBP2,MAP3K12,FZD3" Drug 5980_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.41E-04 1.00E+00 2.92E-03 3.33E-02 48 188 "ACTN2,ADRA1D,PLA2G6,MRTFA,APAF1,APOC1,PPFIA3,NRP2,BMPR1B,IL33,BTRC,VCAN,ATN1,OPTN,EFNA3,EGFR,MBNL2,ING4,ETV1,FGFR1,CAMSAP1,LILRA2,STON1,KLF12,KCNQ3,MARK1,MATN3,MMP16,PALM,CDK18,PLP1,BCAS3,PTAFR,TMEM231,KCTD17,KIRREL1,STK32B,SH3BGR,HKDC1,AMBRA1,KIF13A,WDTC1,TROVE2,MAPK8IP3,SEMA4A,TBL1X,THRA,VAV2" Drug 6451_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.41E-04 1.00E+00 2.92E-03 3.33E-02 48 188 "ADD3,ANK3,ARRB2,KRIT1,MAGI1,SRSF11,EPS15L1,RAB26,DCAF8,KIAA0586,MFAP3L,PARD6A,RABGAP1L,SIDT2,VPS13B,STX2,SYNCRIP,CINP,STON1,GPER1,BRINP3,ITPKB,JAK2,MAP4,MEIS1,MMP16,MPP2,NCAM2,PBX1,PKIA,SYTL2,RIPOR1,ZDHHC14,NEK11,LGR4,ERC1,CLASP2,TTBK2,SYT1,TACC1,KAT6B,TPD52,RUNDC3B,SSBP2,UBTF,XRCC4,REEP1,ZNF248" Drug 4289_UP 0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "SPARCL1,AMPD3,AMT,PKP4,APC,ASPH,CADM3,ADAM23,BCL7A,SYNJ2,CBFA2T2,JAM2,RIMS2,EDRF1,PHYHIP,SPOCK3,EDN1,SEMA3D,REEP2,RUNDC3A,RAB30,GPM6B,GPR17,DIDO1,GRIK3,GRM8,KCNJ3,MDM4,CD200,ADAM22,PDE4A,PDGFRA,RC3H2,PPARA,MAPK10,CCDC40,PBRM1,SLC2A5,ZC3H13,ACSBG1,VAMP1,ZFPM2,TRIO,ZMYND8,OSBP2,FLRT2,FLRT1,WNK1,SLC30A4" Drug 7097_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "BRAP,CASK,ARNTL,ASPH,FUBP1,RAB29,CLTB,SLC4A7,AKAP12,FAM169A,DOCK4,TBC1D5,DBT,ZBTB24,RBM12,EGFR,CAMSAP1,GAD1,NUDT21,GRB10,KLF12,HSF2,IL6R,DIPK1A,KIF2A,PAXBP1,MAP4,NFE2L2,NFYA,NME4,SLC11A2,PDE1C,NLE1,PLEC,RC3H2,TNPO2,POLG,PPP2R5C,RGS4,USP33,SON,TAB2,SS18,ERBIN,TCF12,UBE2H,LMF1,KLC2,WNK1" Drug 2930_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ABAT,MRTFA,PPFIA4,APBB2,CASK,ARRB1,MARK4,ADAM15,SYNJ2,CAMK2G,CAPN3,SCARB1,HDAC9,E2F5,EIF1,CDKL3,NOP56,ERAP1,ADAM28,PADI2,IL6R,KPNA5,MATK,MDM4,MEST,NFYA,NRGN,NUCB1,NUMA1,OGG1,OPA1,KCTD15,ZSCAN32,RASA3,PPM1E,DZIP1,MYH15,STX1A,KANK1,KAZN,PDLIM2,TCF7L2,NSD1,TMOD1,R3HDM1,TPM2,HSPBP1,UBTF,SYNC" Drug 4725_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ASPHD1,NME5,ANK3,EPB41L5,ATM,SYNJ2,SOCS6,CHM,QKI,SULT4A1,SLC4A7,RCHY1,CTH,MAML1,GIT2,EXOG,ATN1,EDNRB,FCF1,NCALD,CEND1,FER,ANKFY1,GALC,GLYR1,RAB30,GPD2,IL6ST,KCNH2,KCNJ3,MAP2,KITLG,ADAM22,MSR1,CNOT4,SERPINI1,STRN3,LRP12,PMS2,TNPO2,C1orf54,ZFHX4,ARHGAP26,SS18,VAMP1,TCF7L2,TMPO,FLRT2,ZNF24" Drug 4394_DN Levodopa [59-92-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ADD3,ADORA2A,MRTFA,AMT,APLP1,APP,MARK4,CFAP410,SPAG9,NEURL1,ARHGEF2,SDC3,MFAP3L,HP1BP3,EXOG,HIPK3,PLEKHO1,KIAA1109,FGF13,FHL1,HBS1L,GLYR1,RAB30,PCLO,CNTRL,ICA1,TJAP1,IL6ST,KCNN2,KITLG,ADAM22,ZNF862,NF1,SERPINE2,ZSCAN32,PEX5,ATG16L1,PPP4R3A,FAM214B,LIMCH1,NXT2,AJAP1,MCF2L,EXOC7,TMOD1,TRIO,VLDLR,MAP3K12,ST7" Drug 5628_DN Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ALCAM,AMT,EPB41L5,FAM131A,MARK4,SLC4A4,ARHGEF2,FOXN3,NMT2,STOML1,DTNA,PHF20L1,COQ7,FAM198B,EFEMP1,KIAA1109,FGFR1,GLS,CACFD1,IL6ST,KIF2A,MPP2,NFYA,OGG1,CCSER2,NLE1,SLC25A23,LRP12,PRODH,PRPH,NKAIN1,CEP97,ZCWPW1,RGS12,SEC61A2,SBF1,ABLIM3,EPN2,WDTC1,MAPK8IP3,SUPT5H,TBL1X,DMXL2,PSD3,TK2,CDK20,FAM155A,WNK1,SLC17A7" Drug 3474_UP Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "SYN3,AP2A2,AK2,GAS7,ARHGDIG,CFLAR,GYG2,CACNB2,CAMK2B,RCBTB2,STOML1,DNAJB5,ENTPD4,ABCG1,CSF1R,NOS1AP,RUSC2,EFNA3,EGFR,SORBS3,VPS13B,RRAGB,FGFR1,CAMKK2,GPR153,SRCAP,C1QL1,DIDO1,IL6ST,KCNN1,MAN2A2,BCO1,NDUFA5,NF1,NTRK2,PRKAR1B,RGS12,TCP11L1,RPS6KA2,ITSN1,SMARCD3,SNCA,ZHX3,CDK19,ZBTB43,EXOC7,WNK1,EVI5,TIGD6" Drug 7315_UP Isotretinoin [4759-48-2]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "DPF1,SPARCL1,MRTFA,APC,EPB41L5,GAS7,APOC1,CDK10,CDK13,ALDH7A1,ATP6V0A1,RUNX1T1,EPS15L1,NMT2,SULT4A1,AKAP7,CREM,DNAJC6,RUSC2,SIDT2,DLC1,IQCG,GABRA2,ZNF44,GAD1,SRCAP,GNAO1,SPACA9,NDP,NEFH,PALM,PDE4D,ABCB1,MAPK3,WDR25,PEX5,RALGDS,RGS4,TTLL7,NLGN1,SLC11A1,SNCA,DOK5,ZHX3,ARHGAP26,MAPK8IP3,RPGRIP1L,TIAM1,XRCC4" Drug 2209_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ASIC2,C1QTNF1,MRTFA,BIN1,APC,DNAH17,ATM,CFLAR,BTRC,CAMK2B,CD86,RCHY1,SIPA1L1,VCAN,RABGAP1L,DRP2,EDNRA,HIPK3,AASS,SPEG,FOXG1,AGAP2,OGA,GCNT2,ADAM28,GNG3,BTN2A1,SMAD1,CNOT4,PIK3R1,PLCD1,MAPK7,GON4L,SH3GL3,ASAP3,DOCK10,SLC2A5,BTBD7,OGDHL,SPP1,NXT2,MAPK8IP3,VAMP1,ADGRL3,DOCK9,ZMYND8,LAT2,XRCC4,NT5M" Drug 3434_UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ARID1A,APOC1,SEMA4G,CDK13,ALDH4A1,SLC2A11,GYG2,MAP7,ZFYVE9,CSF1R,EDRF1,DLG4,RCAN1,ELAVL3,EPB41L2,ACSL4,KAT8,FER,KIAA1109,FHL1,OGA,SRCAP,RUNDC3A,GLYR1,GRIN1,GRM7,GSN,KCNJ3,MDM4,NFYA,PDE3B,MAPK8,WDR25,RAB3IL1,TRA2B,SHANK2,BTBD7,WDTC1,ZNF423,IQSEC2,SRPK2,NXT2,PLCB1,OBSL1,TMOD1,VIPR2,VLDLR,ZNF24,MAP3K12" Drug 7176_UP Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "MRTFA,APC,ATM,SCAPER,BTRC,CAMK2B,MAGI1,GPR37L1,LHX2,FADS2,QKI,GIT2,DTNA,MBNL2,PLXNC1,IRAK4,COQ7,BAIAP2,DISC1,MALT1,GLYR1,KCNMB4,NR3C1,ATXN2L,KCNH2,MPP2,MSR1,NF1,CNOT4,PDE4A,GON4L,RALGDS,RGS12,SBF1,CNKSR2,PPP4R3A,SLC15A2,ZSWIM8,ERC1,INKA2,ACSBG1,ASTN2,SEMA4A,AHCYL2,ZMYND8,VAV2,ZNF45,ZNF74,SEMA3B" Drug 4630_DN Hycanthone [3105-97-3]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ARID1A,CDK13,PDE8B,STX16,ATP2B2,SYNJ2,CACNA1I,BTRC,CFAP410,MAP7,SCARB1,RAB28,ABCG2,AKAP7,ARMC8,DZIP3,CTNND2,TBC1D5,DBT,MFAP3L,TOM1,EDNRA,FCF1,EFNA3,ZNF589,GAD1,B4GALNT1,GLYR1,MSL3,CACFD1,HAS2,HNMT,NDP,NUMA1,MBOAT7,PRPH,SYTL2,PTHLH,PTPRN2,TRIM68,SLC1A7,ZKSCAN3,KDM4B,TSNAXIP1,NXT2,TCF7L2,SZT2,NSD2,NAV3" Drug 4286_DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ASIC1,NME5,C1QTNF1,APC,CDK10,PPP4R4,ALDH4A1,SYNGR3,CHN2,NIPBL,IQCK,ARMC8,TCEAL2,CRMP1,ARMCX2,DMPK,DTNA,DUSP9,SIDT2,SORBS3,PLEKHO1,ERCC2,ETV1,TUBB4A,FGFR1,BAIAP2,HPCAL4,FLT1,DLL3,DENND2A,POLL,ITIH2,KCNMA1,KIF5C,NTRK2,PALM,PDE4A,PPP2R5C,PPP5C,RAB3IL1,RALGDS,MAPK12,KDM4D,ELMO2,CDK5RAP2,SPTB,ARHGEF12,VIPR2,SEMA3B" Drug 3562_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ABR,PKP4,ATP2B1,CFLAR,KRIT1,SLC4A7,BAG4,GIT2,DBT,FBXL5,LYPD1,DMPK,NR1D2,FCF1,F3,PCYOX1,FAM49B,MAP4K5,HNMT,AGFG1,JAK2,IPO5,MAP4,NFYA,PIK3R1,MED1,PRKAB2,PKN2,TMEM104,PTCH1,PTK2,ARID4A,SLC25A36,RNASEL,GSTCD,CLIP1,PPP4R3A,ZNF430,BTBD7,RBM34,ZBTB43,SS18,SYT1,ASTN2,TK2,TMPO,ZMYND8,SSBP2,FIP1L1" Drug 6422_UP STOCK1N-35215; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "TKTL1,ADRA1D,BIN1,APBB2,ARNTL,DNAH17,SCAPER,PLAA,ARHGEF6,AKAP7,CREM,ENTPD4,TENM4,DTNA,EDN1,EDNRB,DMTN,EFS,HBS1L,GSTM5,RASSF8,HTR2A,ICA1,IL6R,KCNMA1,KCNQ3,L1CAM,BCO1,NF1,SLC11A2,NLE1,MBOAT7,ZSCAN32,FAM120C,RAB3IL1,C1orf54,RIC8B,MYH14,SS18,RGL1,ROBO3,ZEB1,PCDHGB6,AHCYL2,CRB1,ZNF34,SPHK2,SLC30A3,PRDM10" Drug 2731_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ACTN2,NDRG2,KIDINS220,MTUS1,BMP7,GYG2,CFAP410,CACNA2D1,SLC16A4,SCARB1,CHRNB2,PICK1,CRY2,ABCG1,AATK,RIMS3,TRAPPC9,FGFR3,FOXG1,FLNC,TACC2,PRELID3A,NSG1,ADAM28,GFER,GPM6B,GPR19,ICA1,MDM4,ADAM22,SLCO1C1,NTRK2,PBX1,POU3F4,KCTD17,MYH14,NEK11,SYNDIG1,KCNIP1,AMBRA1,SPART,TCF4,TF,TGFBR3,AMACR,ZKSCAN5,FLRT1,STMN4,SLC17A7" Drug 3213_DN Colchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "APOC1,BCAS1,APP,ARHGDIG,ARRB1,CDK13,MTMR2,BTRC,SCARB1,TAOK2,AKAP12,LRIG1,PDE4DIP,CTH,GIT2,NR1D2,SLC12A6,FCF1,ING4,DMTN,KIAA1109,OGA,GALC,POLL,HSF2,KCNJ3,LIG4,MBD1,KITLG,ADAM22,NASP,NFYA,SLC11A2,NUMA1,PCDH9,PDE4A,STRN3,TMEM104,RGS12,RNASEL,TRAPPC13,IQSEC2,TROVE2,NCDN,PCDHA6,NPL,ZBTB14,REEP1,RNF146" Drug 7490_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "LTBP4,SYT13,APBB2,APOC1,APP,PRX,ADAM15,CFLAR,MTMR3,CACNG1,NEURL1,ARHGEF2,NRXN3,CLCN4,TPP1,TBC1D5,DAPK3,SPOCK2,HP1BP3,HIPK3,FEM1B,ING4,KIAA1109,FHL1,RND1,GLYR1,GNAS,STON1,GPER1,GRK4,PCLO,INPP5B,LSS,MDFI,KITLG,NF1,PTN,ZFHX4,CARF,FNDC3A,BTBD7,SLC20A2,LIMCH1,SNCA,SPART,RGL1,VPS13A,PSD3,SENP7" Drug 4616_DN Bisacodyl [603-50-9]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.43E-04 1.00E+00 2.92E-03 3.33E-02 49 193 "ABR,MRTFA,SHROOM2,MARCH3,SYNJ2,MYRF,KRIT1,ARHGEF1,TAOK2,STOML1,HOMER3,NRG2,CPS1,FAM169A,SLITRK5,ARHGAP24,ZNF337,KIAA0753,RCAN1,EIF5,ZNF589,POLR1B,SEMA4D,ANKFY1,ZNF274,ZNF276,GUCY1A1,MUM1,DIPK1A,KIF2A,MITF,NDP,CCSER2,ZSCAN32,PTPN13,PTPRN2,RALGDS,TRIM68,ZNF365,LIMCH1,COLGALT2,CEP68,PLCB1,IQCE,SMUG1,NSD2,NDRG4,ZFAND5,FZD3" Drug 4530_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY2,SEMA6A,BCAS1,CDC14B,PPP4R4,ARHGDIG,CDK13,ZSCAN18,ADGRB1,ADGRB2,MTMR3,BTRC,RUNX1T1,ARHGAP33,ADGRG1,NRG2,SRGAP3,EIF4G2,ING4,ETV1,ZNF589,CAMSAP1,HPCAL4,SRCAP,GPM6A,MDFI,NEFM,PDGFRA,WDR25,PTPRN2,TMEM231,SLC6A15,RGS7,TMEM206,KANSL3,SLC9A5,ZNF334,SOX15,ZNF423,RBM26,SYT11,ADGRL3,ZEB1,TRIM2,PCDHA3,TPM2,VAV2,NT5M,PARP6,KCNAB1" Drug 4074_UP Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADD2,MRTFA,BEGAIN,AQP4,PPP4R4,BMP7,MYRF,BAIAP3,HIP1R,NRXN2,STOML1,VAX2,PCYT1B,CSF1R,CNTNAP2,ECE2,C2CD2L,ARNT2,USH1C,TNK2,NCALD,CEND1,GABRA1,ATP8A2,NEU3,GPM6A,HPSE2,KCND3,KCNF1,KCNJ4,MAN2A2,MSR1,NPTX1,ENPP2,TMOD2,PRKCB,PTCH1,RYR1,ASAP3,SLC6A11,SLC11A1,SNAP25,SSTR2,CNTN2,TLR4,TNS1,FLRT2,VAV2,KCNAB1,AP3B2" Drug 6300_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASPHD1,ASIC1,ADCY6,NME5,SEMA6A,PKP4,BTRC,CA12,CACNA2D1,CHRNA4,ARHGAP22,LHX2,FADS2,ABCG1,PDE4DIP,FAM131B,DNAJC6,KBTBD11,TOM1,EFNA3,EPHB1,C1orf61,FLT1,PRELID3A,INPP5K,ZNF276,PRUNE2,STON1,HSF2,IL6ST,MAN2A2,NUMA1,CLDN11,PFKFB2,SPATA6,RAB3A,RAB3IL1,ENOX1,SCN8A,ZNF821,DOCK10,SLC20A2,MAPK8IP3,ARHGEF9,TIAM1,BHLHB9,TNS1,UGT8,WNK1,KCNAB1" Drug 2786_DN Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "AP2A2,CDC42BPA,APOC1,CDC14B,ALDH4A1,SCAPER,CACNA1D,QKI,SLC4A8,CSNK1E,PDE4DIP,CNNM1,EZH1,ACSL4,ZNF589,MPP6,SYT17,SRCAP,HTATSF1,IL6ST,KCNH2,MITF,ZNF862,SLC11A2,NUMA1,PDE4A,STRN3,MBOAT7,TTC13,RGS10,MRPS18A,MYH14,ZKSCAN3,WDTC1,ERC1,MAPK8IP3,TTBK2,PDLIM2,DMXL2,PCDHA6,ZNF34,TIAM1,TMOD1,CDK20,PLPPR2,LMF1,ZNF45,ZNF142,REEP1,HPS4" Drug 4282_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,AP2A2,PLA2G6,PKP4,PPP4R4,ASPH,SLC4A4,NRP2,CACNA2D2,PLEKHB1,AKAP7,TCEAL2,SH2B1,CRY2,EDIL3,MBNL2,EIF5,PTK2B,PRELID3A,OGA,INPP5K,SRCAP,GLRB,POLL,RASSF8,SHISAL1,IL6ST,ITIH2,KCNMA1,NF1,NFIX,CNOT4,NUMA1,RETREG1,STRN3,PID1,RAD51D,NEK11,BTBD7,SNCA,TROVE2,ZC3H4,EHBP1,TMPO,R3HDM1,LAT2,SF1,WNK1,EVI5,SENP7" Drug 6455_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SEMA6A,AMPD3,APBB2,KIF1A,CHI3L2,WHRN,CREM,CSF1R,GPRASP1,DGKG,CDON,EDNRA,AASS,LRRC23,F5,FER,KIAA1109,FGF13,INPP5K,SRCAP,GPM6B,PCLO,RASSF8,HAS2,KCND3,KCNH2,KCNMA1,MMP16,ADAM22,NDUFA5,NEFM,PAX6,DUSP26,PHKG1,SLC25A23,PTCH1,RGS12,KCTD17,TCP11L1,ST6GAL1,LIMS2,RBM26,COLGALT2,POPDC3,PRMT8,FLRT1,WIPF1,NSD2,ZNF711,SLC30A3" Drug 2730_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADRA1D,DOC2A,BIN1,NUMB,SCAPER,LDLRAD4,EPS15L1,NRG2,NCOR1,CSF1R,DCAF8,CTIF,MFAP3L,DTNA,MTSS1L,KAT8,INPP5K,SRCAP,GPR75,POLL,LSS,SMAD1,MYT1,NNAT,OLR1,CCSER2,RC3H2,POU6F1,PRKCZ,TMEM104,FAM120C,FAM184A,ZFHX4,PAQR6,ITSN1,SLC12A2,TMCC1,KDM4B,DOP1A,ARHGAP26,TROVE2,FCHO1,KAZN,TCF7L2,OBSL1,R3HDM1,UBTF,CLIP2,MAP3K12,TIGD6" Drug 1907_UP Captopril [62571-86-2]; Up 200; 17.2uM; PC3; HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ACLY,ZBTB10,NUMB,N4BP2L1,CANX,CLDN10,FOXN3,IQCK,CDC42BPB,AKAP12,DAPK1,SPOCK2,SPATA2,FBXL5,KBTBD11,DLG3,ABI1,DTNA,FEM1B,STX2,WAC,ACSL4,KIAA1109,SEC23B,ALDH1L1,CRCP,GNAO1,PRRC2B,RNFT2,ARHGAP19,KLF12,NEUROD2,KCTD15,NLE1,ZNF426,TRHDE,MAPK10,NUDT11,RPRD1A,FAM192A,ITSN1,EMC1,EPB41L3,VPS13A,OBSL1,ZMYND8,UBE3A,EVI5,GDPD5" Drug 7279_UP Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY6,MTUS1,ALAD,APP,CASK,ARRB2,MARCH3,CFLAR,RAB29,RAB28,CLCN4,ENTPD4,CTNND2,GIT2,LYPD1,SMG7,RABGAP1L,EDIL3,IRAK4,ERCC2,TESK2,FGF1,TRMO,ERAP1,SYT17,DIPK1A,INPP5B,KIF2A,KIF5C,NUMA1,PIK3R1,PTPN13,TMEM231,RAB3A,ROGDI,ZDHHC14,WDR37,SIRT2,WDTC1,TAB2,SS18,DIP2A,WWC1,CABIN1,ZBTB38,EMSY,UBE3B,KAT6A,PHTF2,AAAS" Drug 4323_UP Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASPHD1,ASIC1,ACTN2,SLC12A5,BEGAIN,SEMA7A,APC,ASCL1,BMPR1B,FUBP1,BAIAP3,CACNB2,THSD7A,STOML1,RIMS3,CTIF,DCT,EZH1,KAT8,HPCAL4,GPR153,TRAF3IP2,RND1,GPM6A,NELL2,NPR2,NPTX2,NTRK2,PCSK1,RETREG1,TNPO2,FSD1,GRAMD1C,ZMAT4,RGS4,ZNF821,DZIP1,DHX30,FAM214B,SLC15A2,SNCB,IQSEC2,THSD1,PLCB1,SYN2,CABIN1,CDK20,CHST5,ZKSCAN5,SLC13A3" Drug 5837_UP Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADGRF5,AMT,APOC1,PPP4R4,SLC4A4,ALDH7A1,RAB29,CFAP410,HAP1,LARGE1,CNOT8,USP6NL,DCAF8,GIT2,CDON,ATN1,EFS,ABCA8,FGFR1,SEMA4D,EFCAB2,PDLIM5,DISC1,GLI2,GLRB,ADAMTS13,KCND3,LAMA2,LIG4,MAN2A2,NF1,SNTG1,PIK3R1,MAPK3,BCAS3,PTN,RGS10,SUGCT,NEK11,WDR37,KDM4D,SMARCA4,SPTAN1,COLGALT2,SS18,PCDHA5,AP4E1,LILRA4,SLC17A6,DPF3" Drug 3235_UP Chlormezanone [80-77-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ACTN2,ARID1A,BEGAIN,TRMT9B,APAF1,ATP2A2,ALDH7A1,BTRC,CA4,CACNB4,CHM,BAG4,RIMS2,EDRF1,ARMCX2,ZNF804A,EFNB3,VPS13B,NCALD,SPEG,ZNF589,FGFR1,PRELID3A,ALDH1L1,C1QL1,GLYR1,RAB30,IRF8,KCNN1,MDFI,MOBP,MYL3,NPPA,PDE4A,PURG,PPP5C,MAPK10,PRODH,RGS4,SLN,SOX2,IZUMO4,ZC3H13,TRIM2,PCDHGA1,PSD3,AP4E1,MVB12B,ADAMTSL3,AP3B2" Drug 6599_DN 5194442; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "EPB41L5,CDC14B,ARHGDIG,BMP7,SYNJ2,CACNA1I,CA4,CACNA1D,SCARB1,VAX2,IQCK,BAG4,PDE4DIP,ARHGEF4,EDRF1,DGKG,DBN1,MFAP3L,LYPD1,EPB41L2,GLS,GNG3,TDRKH,EML4,CNTRL,ELOVL5,NDUFA5,NF1,CDK18,PDE3B,FAM120C,BCAN,LIMCH1,KDM4B,SPART,ARC,PDLIM2,TBCEL,SMG6,TCF7L2,TRIM2,SZT2,TMPO,RBFOX2,TPD52,HIRA,MICAL1,ZNF24,WNK1,PRDM2" Drug 2328_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG2,SPARCL1,APAF1,APC,DNAH17,RASL11B,GYG2,BTRC,KALRN,CDH2,ARHGAP33,CLGN,CPS1,DTNA,DYRK1A,OLFM1,FGFR1,BAIAP2,TPK1,GPR162,GLS,POLL,GPM6A,NR3C1,IRAK3,ICA1,ITGAM,KCNJ5,KCNMA1,MAP4,ADAM22,MYT1,NCAM1,NNAT,PLTP,MTRF1L,APTX,FAM120C,C1orf54,SLC30A10,BCAN,SLC1A7,SOX2,SPART,ATP10B,KIAA0930,SZT2,OBSL1,FAM155A,REEP1" Drug 6354_UP Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,NME5,PPP4R4,ARRB2,DNAH17,MARK4,ALDH4A1,KIF1A,ST3GAL5,DNAJB5,SULT4A1,WHRN,IFFO1,ENTPD4,CSF1,SLITRK5,CTNND2,B3GAT3,E2F5,SGK2,EFNB3,CELSR3,FAM13A,EGFR,IRAK4,C1QL1,GPM6A,IL6ST,KHK,VWA5A,CNOT4,NOVA1,PALM,PDE2A,FSD1,PROX1,PSMD13,ELOVL2,CCDC40,RGS7,SH3GL2,NLGN1,SLC2A5,ELMO2,KDM4C,LHPP,ATP10B,PHLDB1,ARHGEF12,MVB12B" Drug 5937_UP LY294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ARID1A,NDRG2,PLA2G6,SPARCL1,BBOX1,KSR1,MYRF,CACNG1,CALB2,CAMK2B,AKAP7,SLC4A7,NRG2,SNCAIP,CSF1R,PDE4DIP,DMPK,ST8SIA3,AASS,SORBS3,ING4,LRRC23,ATP8A1,AGAP2,GAD2,ATP8A2,PCLO,CACFD1,GRM3,FAM107A,ICA1,VWA5A,NEFM,SLCO1C1,NFYA,PENK,RETREG1,PROX1,RELN,RPS6KA2,ELMO2,ZHX3,ZC3H13,SS18,TEX15,TNS1,PRMT8,UBE2H,CLIP2,NUP214" Drug 2327_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY2,NME5,BIN1,APC,ASPH,CADM3,CFLAR,BTRC,TAOK2,FADS2,CREM,OSBPL3,SNPH,ARHGAP24,MFAP3L,DSCAM,EDNRA,ING4,ERCC2,TUBB4A,FGFR1,GUCY1A2,ICA1,KPNA5,LSS,NF1,NNAT,OPCML,OPRL1,SERPINE2,PLCD1,MTRF1L,MAPK10,PRODH,RELN,PTPRO,FAM120C,RAB3IL1,CCDC40,KLHDC8A,GSTCD,SLC1A2,SLC6A8,ARC,PCDHGA10,RALYL,PSD3,TMOD1,PARD3,MVB12B" Drug 6440_UP AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "BIN1,AMT,BCL7A,SCAPER,KRIT1,CBFA2T2,CRY2,ABCG1,DMPK,SIDT2,LPAR6,EN2,ANKMY1,ZNF589,SCARA3,SORBS1,GLRB,GRIK2,GRIK5,CACFD1,IFI16,ITIH2,TM6SF1,CDK18,PDGFRA,SERPINI1,SNRK,SUGCT,RPS6KA2,SH3BGR,KIF16B,RAB3GAP1,SLC20A2,IQSEC2,PLCB1,SYT1,ATP11A,EXOC7,KIAA1107,TRIM2,HEY1,CHST5,TRPC1,ZNF74,SPHK2,SYNC,EVI5,HPS4,URM1,DPF3" Drug 336_UP nitrendipine; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ALK,BIN1,CDC42BPA,APBB1,KCNAB2,ARNTL,CAMK2A,SCARB1,LHX2,ATN1,USH1C,FAM13A,EPHB1,BAIAP2,FGR,NSG1,PNMA2,TBR1,GAB1,GFRA2,TXNL4A,GLRB,GUCY1A1,ATXN2L,TAGLN3,NF1,NPR2,SLC11A2,NRGN,GPR173,MAGEL2,POU6F1,MASP1,CNTLN,KCTD17,FOXRED2,FRMPD1,ZNF365,SLC6A11,SNCB,ZCCHC24,CAND2,CLSTN2,TBL1X,PARD3,RBFOX2,WIPF1,PRDM2,MVB12B,AAAS" Drug 7457_UP Bromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ADORA1,NME5,APOC1,ARHGDIG,SLC4A4,ALDH7A1,SCAPER,SOCS6,ZFYVE9,CNTN1,CSF1R,PDE4DIP,CNTNAP2,MFAP3L,DYRK1A,EFNB3,CELSR3,MBNL2,OLFM1,C1orf61,OGA,IFI16,KCNJ5,LAMA2,MDM4,MIA2,LYRM9,NPTX1,NTRK2,OMG,RETREG1,EPN1,PLXNB1,MBOAT7,WDR25,GAL3ST4,RGS3,GSTCD,SBF1,ZNF821,LMO3,MCF2L,TRIM2,TLR4,PARD3,TRPM2,KCNK12,TFIP11,GDPD5" Drug 5253_DN Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG2,ALCAM,ALK,APC,APP,DNAH17,SYNJ1,BTRC,CACNA1D,CACNB2,FOXN3,ZFYVE9,HOMER3,ARMC8,CNTNAP2,PHF14,RASSF2,DRD1,PIPOX,ANKMY1,KAT8,ZNF589,FGFR3,IQCG,RAB30,GPR19,RASSF8,HSD17B1,VWA5A,MAPT,MMP16,MPP2,WDR25,RGS10,ZFHX4,DOCK10,SLC9A5,CXXC4,SNCA,ZCCHC24,ZC3H13,PLCB1,EXOC7,TBCEL,WSCD1,PSD3,ZBTB14,EVI5,FIP1L1,ADAMTSL3" Drug 6930_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "RBM10,ABHD6,AP2A2,SEMA6A,MRTFA,APBA2,APBB2,ARHGDIG,CDK13,ATP6V0A1,CACNA1D,WHRN,AKAP12,CSF1R,VCAN,PDE4DIP,HDAC4,SPOCK3,DTNA,EGR3,PLEKHO1,LRRC23,CAMSAP1,OGA,FYB1,ZNF44,INPP5K,GLI2,TDRKH,C2orf72,MATK,ADAM11,MEIS1,MMP16,MTRF1L,GON4L,WDR25,RAD52,ROM1,SLN,RBM34,IQSEC2,CLSTN2,CEP68,ARHGEF12,TK2,VLDLR,NAV2,PARP11,FAM13C" Drug 702_DN alpha-estradiol; Down 200; 0.01uM; PC3; HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ACTN2,AP1B1,SYT13,APBA2,CDK10,SLC4A4,NRP2,CDC42BPB,NCOR1,SDC3,INTS1,B3GAT3,ELAVL2,BSCL2,HSD17B14,DMTN,TMEM164,HPCAL4,C1orf61,SEPT9,INPP5K,TXNL4A,OS9,GPR12,RASSF8,HMX1,AGFG1,KCNJ5,KIFC3,MAP4,GIT1,ADAM22,NELL2,OMG,PLCD1,MBOAT7,POLG,PPP5C,RAP1GAP,RAP1GDS1,RLBP1,NUDT11,UEVLD,RPS6KA2,MAPKBP1,SON,MLST8,CBX5,AAAS,DPF3" Drug 4378_DN Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "RALGAPA1,ABHD6,KIAA1324,MRTFA,BIN1,APC,CDC14B,MARK4,BRINP2,CACNA1D,CNTFR,WHRN,SH2B1,NCOR2,DMPK,MBNL2,PIPOX,PTK2B,ZNF589,OLFM1,SCARA3,FOXG1,DISC1,GNAS,ATXN2L,ICA1,KHK,LYRM9,NEUROD1,CDK14,POU3F2,GRAMD1C,CCDC40,ZDHHC14,TRIM68,RGS10,RASA3,SH3BP2,DOCK10,SNCA,WDTC1,CRTC1,HEY2,TRPM2,UBE3A,PDIA2,VAV2,VIPR2,PRDM2,ITM2C" Drug 5453_UP Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SLC12A5,ADORA1,SYT13,BIN1,CADM3,LDLRAD4,CACNA1D,CD86,CHM,SLIT2,SLC22A6,ARHGEF4,JAKMIP2,SPOCK3,TRAPPC9,ABCC9,ZNF391,BAIAP2,DKK3,SIGLEC8,ALDH1L1,C1QL1,GNG3,GPD1,PRUNE2,GRM1,GUCY1A1,ATXN2L,KIT,MAP4,NF1,OPCML,KCNK10,PCSK5,PDE4A,MINDY2,MAPK7,PTCH1,PTHLH,PTPRO,KLHDC8A,WDTC1,ZHX3,ROBO3,TRIM2,PCDHGB6,TRPM2,DNAJC12,CLIP2,ZNF711" Drug 2138_UP Palmatine chloride [3486-67-7]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SYN3,ASIC1,ADCY2,KIDINS220,FAM135A,ALK,DOC2A,BIN1,CDC42BPA,APOC1,N4BP2L1,ADGRB1,CACNA1I,AATK,RUSC2,NTM,TMCC2,TRAPPC9,LRRC23,REEP2,KIAA1109,CAMSAP1,DLL3,TMEM8B,SIGLEC8,ALDH1L1,ZNF276,GPER1,GRIK5,RASSF8,PADI2,HNMT,KCNN1,LAMA2,ZNF862,ST8SIA5,PTPRN2,NEK11,FRMPD1,CDK19,ST5,INKA2,PHLDB1,PCDHGA1,GPR161,TJP1,TPM3,PRMT8,VSNL1,SPHK2" Drug 4808_DN Benzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABHD6,BIN1,CDC14B,STX16,MTMR3,MTMR2,HAP1,MAP7,MAGI1,LHX2,AKAP7,USP6NL,SMG7,ATN1,EDNRA,OPTN,MRNIP,SCML2,CAMSAP1,FHL1,FAM49B,PRELID3A,GAD1,COPS8,MAP4K5,DHX35,IPO5,MAP4,MITF,LYRM9,NEK1,PDE3B,RC3H2,PTHLH,FAM120C,CEP97,RGS12,KCTD17,WLS,ANKRD6,CDK5RAP2,EMC1,TTBK2,SEMA4A,ROBO3,DOCK9,AHCYL2,TMEM121,VGF,XRCC4" Drug 1518_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ADRA1B,APAF1,MARK4,CFAP410,CDH8,SOCS6,HOMER3,BAG4,ENTPD4,VCAN,RIPOR2,ARHGAP24,RIMS3,GIT2,SIDT2,ING4,CEND1,GFER,TXNL4A,POLL,GPM6B,PCLO,GRM1,GRM7,IL6ST,ITPKB,MOBP,PCBP3,OPCML,CDK18,RETREG1,LRP12,SPATA6,RAB3IL1,RAD52,SEC61A2,SLC1A2,ZKSCAN3,CDK5RAP2,WDTC1,PEG10,SPTB,CDK19,SPART,PHLDB1,SLC44A1,DAAM2,CHST5,ZIC3" Drug 6254_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "PLA2G6,BIN1,GAS7,ADAM23,GYG2,REPS2,CHRNB2,STOML1,QKI,WHRN,DOCK4,RIPOR2,LYPD1,DTNA,TOM1,EDNRB,ELAVL2,COQ7,SPEG,KAT8,FHL1,AHDC1,HPCA,INPP5B,KCNMA1,ADAM22,NPR2,PPP2R5C,PPP5C,CNNM2,NKAIN1,ZCWPW1,SH3BP2,ITSN1,CNKSR2,SMTN,SLC9A5,SNCA,ZCCHC24,ZNF423,SPART,PHLDB1,ARHGEF9,PLCB1,ADGRL3,TBCEL,KIAA0930,AHCYL2,VAV2,SPHK2" Drug 5775_DN Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "AP2A2,CDK10,MARK4,SYNJ2,ENTPD6,CDC42,CREM,HAPLN1,CSF1,CSF1R,DZIP3,C2CD2L,SIDT2,SORBS3,EML1,DMTN,DENND4A,DENND2A,FERMT2,PRRC2B,GPR37,KLF12,IL6ST,NF1,CNOT4,NPR2,CLDN11,PC,NLE1,FSD1,MINDY2,PPP5C,MAPK7,PTPRE,PTPRH,ATG16L1,NEK11,ZNF671,PAQR6,ITSN1,FBXO11,ELMO2,TROVE2,ELOVL4,CEP68,KIAA0930,HIRA,ZBTB14,EVI5,GAN" Drug 4403_UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG2,ASPH,BCL2L2,CFAP410,CACNA2D1,CAMK2B,CAST,LY86,NCOR2,DUSP9,EFNB3,RASGRP2,KCNMB2,SPEG,ZNF589,FGFR1,CSPG5,GPR162,GRB10,CACFD1,GRM1,ICA1,KCNH2,KIFC3,LAMA2,VWA5A,LSS,MID1,AFF1,NTRK3,PDPK1,CAMKV,EPN1,PLXNB1,NECAB2,PACSIN1,PPP5C,RAB3IL1,KCTD17,SCN2B,ASIC4,ASAP3,HKDC1,SLC11A1,SHANK2,OGDHL,ARHGAP26,HEY2,AMOT,ITM2C" Drug 7291_UP Lymecycline [992-21-2]; Up 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "KIDINS220,PLA2G6,MRTFA,ARHGDIG,ADAM23,CACNA1A,HAP1,IQCK,ABCG1,CSF1R,TOX,FCF1,AASS,DLC1,DENND2A,SPACA9,HSF2,TJAP1,SCIN,KCND3,MEF2C,CNOT4,NRCAM,GPR85,TNPO2,FA2H,MAPK10,WDR25,ZCWPW1,ZDHHC14,RGS10,PAQR6,BCAN,IFT122,KDM4B,DDN,NFASC,LHPP,TROVE2,THSD1,MAPK8IP3,ASTN2,SYNE1,SPX,GPR161,TIAM1,PARD3,OSBP2,XRCC4,ZNF74" Drug 6292_DN Metolazone [17560-51-9]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADD3,ASPH,CFLAR,CDK5R1,AP4M1,CLCN4,NIPBL,OSBPL3,PDE4DIP,KIAA0513,DBT,KIAA0753,G3BP2,FEM1B,ERCC2,SPEG,FER,BAIAP2,CINP,TRAF3IP2,INPP5K,GHR,TXNL4A,GPD2,GPER1,NR3C1,MUM1,DIPK1A,KCNMA1,KIF2A,PC,CDIP1,RC3H2,SYTL2,SH3TC2,CLIP1,AP1AR,SBF1,ASAP3,SLC1A3,FAM214B,ARHGEF40,TMCC1,SEPT8,GSE1,SYT11,FRYL,CABIN1,TFIP11,FZD3" Drug 459_DN copper(II) sulfate pentahydrate; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG2,ADCY6,AP1B1,APBA2,NCOA1,CADM3,ATP6V0A1,P2RX6,SLC24A2,LY86,GIT2,RCAN1,OPTN,EFNB3,SUGP2,ELAVL4,DLC1,HPCAL4,ATF7,BTN2A1,SOX21,RASSF8,ADAM22,NEUROD2,CNOT4,PLCD1,PPM1B,VPS13C,PTAFR,RAP1GAP,SUSD4,RET,ZC3H14,CASC3,SLC2A5,SMARCC2,SON,TNIK,ZHX3,ZC3H13,SPART,CEP68,PLCB1,EXOC7,TBL1X,WASHC4,TNS2,FLRT1,WIPF1,FIP1L1" Drug 2368_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ACTN2,NCOA1,SLC4A4,ATP6V0A1,ADAM23,SYNJ2,SLC25A14,CAPN3,FOXN3,CLCN3,IQCK,HINFP,CTNND1,CX3CR1,DSCAM,DTNA,BSCL2,LRRC23,STX2,IGSF6,F3,F8,FGFR1,ATP2C1,GNG4,LILRB4,CNOT4,RETREG1,ZNF426,MAPK3,SIDT1,TMEM104,RAB3A,GSTCD,FUZ,PPP4R3A,ZKSCAN3,SPATA7,UNC5B,CEP68,JMJD6,AHCYL2,THRA,KAT6B,FLRT2,LAT2,NT5M,PHTF2,NLRP3" Drug 6738_DN Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,MRTFA,AMPD3,LGR5,MARK4,MYRF,LDLRAD4,CBFA2T2,WHRN,SLC4A8,VCAN,RIMS3,PARD6A,DNM2,ST8SIA3,MBNL2,FYN,GAB1,B4GALNT1,COPS8,POLL,GRK4,SYNPO,MIA2,ZNF862,MYT1,NOS1,PLXNB1,MAPK7,APTX,ZCWPW1,DCUN1D2,KIRREL1,PAQR6,TRAPPC13,FOXRED2,DZIP1,MYH15,ARHGAP26,DDN,LHPP,PHLDB1,EXOC7,DOCK9,ARHGEF12,TRIO,VIPR2,ZNF24,TFIP11,PRDM2" Drug 3990_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "APC,APP,DNAH17,ALDH4A1,KIF1A,NRP2,SYNJ2,NRXN3,PICK1,AATK,PDE4DIP,SIRPA,ATN1,DTNA,SIDT2,LRRC23,MTSS1L,AFF2,ZNF44,TRAF3IP2,B4GALNT1,GFER,C1QL1,GPR19,GRM8,SHISAL1,MBD1,NUMA1,PBX1,GRAMD1C,RALGDS,ZCWPW1,KHDRBS2,SELL,FRMPD1,SLC1A7,LIMS2,SLC6A9,SLC9A5,SMARCD3,WDTC1,TNIK,TSNAXIP1,PDLIM2,DNAH7,OSBP2,WIPF1,REEP1,LRP8,EVI5" Drug 5905_UP estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SEMA6A,SEMA7A,ATP1A2,CADM3,CAMK2B,SLC16A4,SCARB1,EPS15L1,TMEM59L,WHRN,CPS1,DRD1,DTNA,MBNL2,EGR3,SPEG,PIPOX,FHL1,GAD1,ZMYND11,GNAS,TDRKH,IL11RA,JAK2,KCNJ9,VWA5A,MGAT3,MOBP,ADAM22,OPRL1,PGAM2,RETREG1,EPN1,PILRA,MINDY2,PPP5C,MASP1,RELN,CCDC40,RPS6KA2,CNKSR2,RPH3A,PLCB1,SYNE1,PCDHGA1,OBSL1,CRTC1,SEZ6L,SLC13A3,KCNAB1" Drug 5992_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,AK2,ALAD,CDC42BPA,NUMB,ATM,CFLAR,LDLRAD4,CA12,LRRFIP1,ABI3BP,CSF1R,CNTNAP2,CTH,RABGAP1L,DTNA,ANKMY1,F8,KAT8,ZNF589,POLR1B,FGFR1,FAM49B,CNTRL,GRM1,GRM8,IL6R,IL6ST,INPP5B,ITPKB,WDR25,PTCH1,FAM120C,MRAS,CXXC4,UNC5B,IQSEC2,SPART,CLASP2,TROVE2,CEP68,TTBK2,PHLDB1,CHST8,TK2,CABIN1,ZFP37,FTSJ1,KCNAB1,MVB12B" Drug 7203_UP Vidarabine [5536-17-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ARID1A,NDRG2,BEGAIN,DOC2A,TRMT9B,ARRB1,MARK4,ATP1A3,AZGP1,SYNJ1,ST3GAL5,CA4,CACNA1D,CACNB4,ARHGEF2,CDH8,CHRNA4,CSF1R,CYBB,CTIF,PARD6A,KCNMB2,FABP7,FGFR1,SEPT9,SRCAP,STON1,GRM8,HNMT,LIG4,ADAM22,ZNF862,CNOT4,SLC11A2,P2RY1,STRN3,PRPH,SAMD9,ATG16L1,RGS12,MRAS,ASAP3,SYBU,IZUMO4,CHST8,TLR4,TMOD1,TFIP11,NT5M,JPH3" Drug 201_DN 15d-PGJ2; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADD2,ARRB2,ASPA,C5,CAMK2G,SCARB1,STOML1,FADS2,NIPBL,HINFP,ARHGEF10,GREB1,SPOCK2,DLG3,ATN1,EFNA3,RBM12,MRNIP,PLEKHO1,LRRC23,ERCC2,TRMO,SEPT9,ARFIP1,ARHGAP19,AGFG1,ICA1,PAXBP1,LMO1,MAP4,MYT1,NUMA1,SETD4,CLDN11,PBX1,PLCD1,PPM1B,TMEM104,EMID1,NUBPL,ABLIM3,SNCA,KDM4B,COBL,ATP11A,TRIM2,BHLHB9,R3HDM1,SEZ6L,FLRT2" Drug 5865_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "BIN1,EP400,MARK4,CFLAR,CNOT8,TAOK2,CSF1,CNTNAP2,ZNF337,GIT2,DBT,RHOBTB1,TMCC2,DYNC1I1,EFNA3,MRNIP,EPB41L2,TRMO,HTATSF1,NR3C1,KLF12,HNMT,JAK2,MEIS1,NASP,CDK14,SLC25A23,RC3H2,ELOVL2,RIPOR1,SH3TC2,BSDC1,SH3BP2,LIMS2,SMARCA4,SPATA7,ZBTB43,SS18,ARHGEF9,PDLIM2,IQCE,FBXW11,ARHGEF12,ZNF34,TPD52,UBTF,SPHK2,ZFAND5,GDPD5,NAV3" Drug 6797_DN Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASPHD1,ADRA1D,AP2A2,ALCAM,PPFIA3,SCAPER,CACNA1D,PLEKHB1,SLIT2,LHX2,TPP1,SLC4A8,AKAP12,FEZ1,ARHGEF10,PDE4DIP,FAM169A,MFAP3L,DSCAM,SORBS3,ING4,ELAVL3,F3,FER,PDLIM5,CGREF1,HTATSF1,POLL,AGBL5,KHK,LSS,SLC11A2,PCDH9,PDE3B,SLC25A23,ELOVL2,PEX5,RAD52,GTDC1,SH3BP2,ARHGAP26,THSD1,TTBK2,PHLDB1,PLCB1,EXOC7,TCF7L2,TRIM2,KAT6B,NDRG4" Drug 2895_DN Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ACTN2,NME5,APC,MARK4,RASL11B,ALDH4A1,HAP1,CAMK2G,SEPT7,ADGRG1,AKAP7,CRY2,MAML1,DAPK3,MFAP3L,LYPD1,PARD6A,DSCAM,DYRK1A,SGK2,EIF4G2,SORBS3,PRELID3A,GPD2,TJAP1,KHK,ADAM22,NPR2,NPTX1,NTRK2,PLCD1,LRP12,TNPO2,PRKAR1B,RELN,CNNM2,PTHLH,FOXRED2,ABLIM3,PREX2,CXXC4,WDTC1,SOX2,ZC3H13,ARHGAP26,PCDHA5,TK2,CDK20,ZFP37,GDPD5" Drug 6041_DN Evoxine [522-11-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "MTUS1,ARHGDIG,CFLAR,BTRC,CAMK2G,KYAT1,SCARB1,SRSF11,PLEKHB1,LHX2,BAG4,CREM,CRY2,FEZ1,PDE4DIP,DZIP3,EDRF1,MFAP3L,LYPD1,DMTF1,DTNA,TOM1,MRNIP,ANKMY1,GALC,TXNL4A,COPS8,DHX35,KCNF1,LIG4,MPP2,OPA1,RETREG1,PTCH1,C1orf109,ROBO1,LGR4,FBXO11,SLC22A4,ZKSCAN3,TMCC1,SPART,THSD1,ELOVL4,NSFL1C,VAMP1,ANKRD12,EXOC7,ZNF34,MPPE1" Drug 5108_UP "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "DPF1,GAS7,CDK13,KSR1,EPS15L1,DNAJB5,SULT4A1,AKAP5,ENTPD4,CRMP1,ABCG1,USP6NL,ATN1,ING4,COQ7,RASGRP2,SPEG,FAM49B,DISC1,ITIH2,KCNMA1,LAMA2,MDFI,MIA2,NDUFA5,CNOT4,MINDY2,GRAMD1C,PROX1,SNRK,FAM120C,ZSCAN2,TCP11L1,RPS6KA2,IL17RB,ZNF821,DOCK10,DZIP1,SLC4A3,SCN3B,KDM4C,ZBTB43,MAPK8IP3,ZNF34,R3HDM1,TNS1,TPM2,VIPR2,LAT2,HPS4" Drug 2803_UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SLC12A5,NME5,APBA2,KSR1,SCAPER,GYG2,SLC16A4,RCBTB2,DBT,DRD1,HSD17B14,DMTN,STX2,F3,FGF12,OGA,SRCAP,GLS,GNG3,TDRKH,GRM7,HLF,ICA1,MAP4,GIT1,NDUFA5,P2RY1,PCDH9,LRP12,SIDT1,PTHLH,RAB3IL1,C1orf54,RGS3,RGS12,STUM,LIMS2,KIF13A,SPTAN1,SPART,ST5,ATP11A,KIAA1107,PSD3,CRTC1,DICER1,CABIN1,TRPC1,ITM2C,TIGD6" Drug 6681_UP Etoposide [33419-42-0]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY2,APAF1,SPTBN4,RGS11,CACNA1G,HAP1,SCARB1,CHM,FAM189A2,DNAJB5,SULT4A1,HOMER3,IFFO1,TCEAL2,CNTNAP2,EDRF1,BRINP1,EXOG,TRAPPC9,DTNA,RGS17,F5,FGF1,GABRA2,GFRA1,GNAO1,GSN,KLF12,KCNC1,MDM4,MIA2,MMP16,MOBP,CD200,NCAM1,NPY,OMG,PDE4D,PENK,PIK3R1,TNPO2,LRRN3,RASGRF1,KCNIP2,FRMPD1,SLC11A1,SPTB,ARHGEF12,UBE3A,SPHK2" Drug 2552_UP Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY2,AMH,AMPD3,OGT,ANK3,AZGP1,KSR1,KALRN,HIP1R,SLC16A4,CDH2,CHRNA4,RGS6,EDNRA,FABP7,FGFR3,FOXG1,GAA,GABRA1,GAP43,SIGLEC8,ALDH1L1,LYVE1,GNAS,GUCY1B1,KCND1,KCNJ5,KCNMA1,ADAM11,NTRK3,POU6F1,ACSM5,SUGCT,PNMA8A,PRR5L,SCN2B,TRIM46,ASAP3,CCDC92,PEG10,CLSTN2,PLCB1,TNS2,THRA,RIMBP2,SEZ6L,PRMT8,TRO,FAM155A,SLC26A10" Drug 7180_DN Meropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "APAF1,NUMB,BCL7A,CFLAR,SYNJ2,MTMR3,CCNT1,UBE2L6,NIPBL,COL9A2,SLC4A7,CSNK1E,FBXL5,RBM12,CELSR3,MFSD10,STX2,FYN,INPP5K,GART,AHDC1,PRRC2B,CLASRP,RBPJ,MAP4,MIA2,NEK1,NRGN,OGDH,PLEC,PLXNB1,MED1,RAB3IL1,BSDC1,RGS10,MYH14,FBXW7,MAP6D1,SEC14L1,CCDC92,MAPKBP1,KDM4C,ATP11A,EXOC7,TCF7L2,TRIM2,ARHGEF12,CHST8,RBFOX2,MVB12B" Drug 6482_DN Benserazide hydrochloride [14919-77-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABR,AK2,MRTFA,AMPD2,APC,APP,CDC14B,CDK10,ASPH,NUMB,C5,KRIT1,SLIT2,NMT2,CREM,MATR3,DTNA,EFNA3,EZH1,F3,FGFR1,PRELID3A,CSPG5,NCKAP1,MSL3,RAB40B,TDRKH,GPER1,BTN2A1,NEK1,PDE3B,PTPRE,RGS10,ITSN1,SLC15A2,TROVE2,CEP68,KLHL7,PLCB1,MTCL1,CAMSAP2,SATB2,PSD3,KCTD2,RBFOX2,UBE3A,VGF,ZNF74,FZD3,ACTR3B" Drug 6297_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NME5,PLA2G6,DOC2A,SEMA7A,BAIAP3,CFAP410,CACNA2D1,SCARB1,CDH8,TAOK2,HOMER3,CSF1,PDE4DIP,BRINP1,EIF4G2,IRAK4,PLEKHO1,STX2,ST3GAL6,ZNF589,FLT1,SORBS1,GLI2,ATF7,GRM1,HSF2,IRF8,KCNB1,MOBP,NUMA1,CLDN11,MINDY2,PTCH1,BEND5,GSTCD,SCN8A,DZIP1,SLC2A5,KIF21B,HECW1,MAPK8IP3,ACSBG1,VAMP1,ATP11A,WNT7A,ZBTB14,NT5M,EVI5,KCNAB1,DPF3" Drug 2020_UP Azacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADORA1,PLA2G6,CDK10,PRX,PDE8B,CADM3,ADGRB2,CA12,CACNA1A,CALB2,SPAG9,CHN2,CNTFR,KIAA0586,TMCC2,TRAPPC9,SORBS3,TNK2,SRPK3,ELN,PIPOX,TRMO,ALDH1L1,GJB1,GLS,SPACA9,CACFD1,KCNF1,MBP,GIT1,NFYA,NUCB1,OMG,DUSP26,CAMKV,RETREG2,PACSIN1,PPP5C,RAP1GAP,RGS12,RXRA,SLC2A5,LIMS2,SYN2,DNAH7,LILRA4,ZMYND8,VGF,VIPR2,NUP214" Drug 5537_UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "BEGAIN,PRX,PLA2G4C,DNAH17,CADM3,CFLAR,SCAPER,CACNB2,CD86,RIMS2,EDRF1,MAML1,CNIH3,TMCC2,ATN1,DSCAM,EPB41,HPCAL4,ERAP1,GNAO1,GPER1,NR3C1,GUCY1A1,ITIH2,KCND3,KCNN1,LIG4,MAP4,MBD1,MYBPC1,NPPA,POLG,PPARA,PROX1,ELOVL2,C1orf54,EMID1,ZNF821,SYBU,FAM214B,ARHGAP26,CEP68,PLCB1,KIAA0930,DICER1,TRO,ZNF24,SPHK2,HPS4,KCNAB1" Drug 7282_UP Meticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "AMPD3,PDE8B,BAIAP3,LDLRAD4,RUNX1T1,B4GALT6,RCHY1,IFFO1,ABCG1,PDE4DIP,CNTNAP2,CTNND2,EDRF1,AK5,EXOG,EGFR,DENND4A,ANKMY1,F5,TESK2,ZNF44,DENND2A,DISC1,POLL,GNAL,GUCY1B1,LSS,SCAMP5,NDUFA5,NF1,NOS1,STRN3,MAPK8,SYTL2,WDR25,ELOVL2,PEX5,RAD52,AMBRA1,SLC1A7,SLC6A9,ZHX3,SPTB,THSD1,ARC,EXOC7,SLC35G2,TEX15,TIAM1,KCNK12" Drug 7168_DN Diazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASPHD1,AP2A2,AK2,APBB2,CDK10,NUMB,ENTPD6,REPS2,FOXN3,HOMER3,CREM,MICAL2,CSNK1E,RIMS3,DLG3,OPTN,SORBS3,EPB41L1,STX2,PDLIM5,OGA,SYT17,SRCAP,PADI2,DHX35,KCNF1,LSS,MAP4,MATK,CNNM2,RAB3IL1,RAP1GAP,RGS10,SEC61A2,UEVLD,MAPK12,FNDC3A,PEX26,SLC15A2,ZHX3,ZBTB43,EXOC7,BEX4,ZNF384,RPRM,PLPPR2,VAV1,REEP1,MAP3K12,GAN" Drug 1482_DN Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABR,NDRG3,AP2A2,APAF1,CDC14B,CDK10,NUMB,KIF1A,C5,SRSF11,CHD1L,CREM,ABCG1,ARHGEF10,PDE4DIP,CTNND1,GIT2,DTNA,SEZ6L2,FEM1B,EML1,FECH,CSPG5,MPP6,USP19,MAP4,MPP2,NFYA,PDE4A,PPP3CC,CNNM2,PTPN13,RAB3IL1,WLS,SBF1,ZFP30,ITSN1,FUZ,FBXO11,ABLIM3,TTC17,TROVE2,KIAA0930,TCF7,ZNF34,BEX4,HIRA,VAV2,VGF,REEP1" Drug 621_DN nocodazole; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY6,ADD3,CDC7,PLA2G6,APP,SHROOM2,MARK4,ATP2A2,TAOK2,NIPBL,RAB26,CTNND2,PPP6R2,C2CD2L,DMTF1,SIDT2,TUBD1,TACC2,FAM49B,CGREF1,SESN1,GFER,DIDO1,CACFD1,AGBL5,DIPK1A,IPO5,OCRL,PBX1,MBOAT7,PPP3CA,PPP3CB,PKN2,RET,RIC8B,FOXRED2,FUZ,FBXO11,ZNF430,ELMO2,USP33,CDK19,CEP68,MCF2L,TCF7L2,OBSL1,ARHGEF12,PARD3,LMF1,MPPE1" Drug 2570_DN Methimazole [60-56-0]; Down 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG3,BIN1,CDC42BPA,ANK3,APC,SLC4A4,CDK5R1,LDLRAD4,CHN2,EPS15L1,CPS1,CTIF,DBN1,C2CD2L,SGSM2,EFNB3,SORBS3,ING4,DMTN,RASGRP2,MTSS1L,DLC1,ATP8A1,SEPT9,WASF3,GATM,SRCAP,COPS8,AFDN,MYO6,CCSER2,EPN1,MAPK7,CNNM2,PLPPR1,FAM120C,MAP6D1,CNKSR2,NCDN,TCF7L2,CRTC1,ATP13A2,CHST8,TLR4,TNNT1,SSBP2,LMF1,MAP3K12,STMN4,TIGD6" Drug 7095_DN SC 19220; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "RALGAPA1,BRAP,MTUS1,BIN1,KCNAB2,SOCS6,HOMER3,WHRN,SDC3,ARHGAP32,GIT2,PARD6A,RABGAP1L,ERCC2,TESK2,FHL1,FAM49B,TPK1,SRCAP,FERMT2,GUCY1A1,GUCY1B1,TAGLN3,NPR2,SLC11A2,PDE1C,PLCD1,POLG,MED1,PPP5C,RAB3A,RFX5,SEC61A2,C12orf49,SBF1,CCDC88A,TMCC1,TNIK,ZBTB43,DIP2A,FBXW11,EHBP1,TRIM2,MTMR14,CIAPIN1,VPS35L,SNX27,SMIM8,ACTR3B,AAAS" Drug 5611_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADRA1D,NME5,SEMA6A,APOC1,CFAP410,SCARB1,FOXN3,CHM,ABI3BP,ATRNL1,PDE4DIP,FAM169A,TBC1D5,KIAA0586,MFAP3L,OPTN,MBNL2,EIF4G2,COQ7,RRAGB,F3,SCML2,FER,CAMSAP1,GABRA2,GLYR1,BTN2A1,INPP1,KPNA5,LSS,MDM4,KITLG,SLC11A2,SERPINE2,SLC25A23,PLXNB1,FSD1,PPP5C,ZSCAN32,RAB3A,RAP1GAP,RAB3GAP1,SLC22A4,WDTC1,ST5,TTBK2,PLCB1,TNS2,CABIN1,TRIO" Drug 6508_UP Isradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "AK2,BEGAIN,APBB2,MARK4,ASTN1,CLGN,QKI,CNTN1,TCEAL2,IPCEF1,USP6NL,RASSF2,SRGAP3,EDNRB,MBNL2,VPS13B,ANKMY1,FGF13,FGFR1,AGAP2,ANKFY1,SORBS1,OGA,RUNDC3A,TXNL4A,HAS2,KPNA5,MAN2A2,MBD1,MYCN,MYT1,PCDH8,CDK14,PACSIN1,RGS4,TCP11L1,PPP1R9A,SLC1A7,SLN,PDZD2,WDTC1,CEP68,PLCB1,CABIN1,TRPC1,TRPM2,NSD2,SLC30A3,SEMA3B,SSPN" Drug 2948_UP Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "MTUS1,BEGAIN,APOC1,AZGP1,CLCN4,RCHY1,CREM,CSF3R,DZIP3,CTIF,CNNM1,EFNA3,C3orf18,RASGRP2,FER,AGAP2,GABRA4,NEU3,GFER,GRK4,SPACA9,ATXN2L,LSS,AFDN,GIT1,PLCB2,PLCD1,PLCL1,PLP1,CEP41,PTPRN2,SEC61A2,SBF1,SLC1A2,FAM214B,SNCA,ZHX3,CDK19,LHPP,VAMP1,MTCL1,EXOC7,PDLIM2,EHBP1,TRIM2,UBTF,BEST1,SLC17A7,ADAMTSL3,TIGD6" Drug 5886_UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ANK2,CDK13,ALDH4A1,ADAM23,CFLAR,CACNA1G,CA8,ARHGEF2,DCLK1,ASIC3,LY86,CSF1,CSF1R,C2CD2L,DSCAM,EBI3,TENM1,LRRC17,SIGLEC8,SEPT9,GNAL,PADI2,KCND3,KCNH2,KCNJ5,KPNA5,ADAM22,NNAT,KCNK10,SNTG1,PPP2R2B,LRRN3,CNNM2,BCAS3,GAL3ST4,KLHL11,ROM1,TCP11L1,DZIP1,SLC4A3,WDTC1,ARHGAP26,TCF4,PCDHGA10,CRTC1,TK2,DAAM2,LMF1,WIPF1,SLC30A3" Drug 3091_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ANK3,APC,MARK4,SLC4A4,KIF1A,BMP7,CACNB4,SCARB1,CDO1,COL9A2,SLITRK5,DZIP3,DGKG,DNAJC6,HIPK3,OPTN,ELN,ZNF549,AFF2,CSPG5,FYB1,GATM,RND1,POLL,GPD2,GRM1,IL6ST,KCNN1,LAMA2,MPP2,MX1,NF1,NNAT,SERPINI1,PLCD1,PLCL1,PTAFR,BEND5,RYR1,SLC2A5,SLC6A8,SNCA,KDM4B,INKA2,PHLDB1,PLCB1,TCF7L2,PLPPR2,LAT2,ZNF74" Drug 5985_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "SYT13,KCNAB2,APC,APP,CACNA1I,CDK5R2,CFAP410,CACNA1D,CACNG1,CAMK2B,USP2,QKI,AKAP5,NCOR2,CHD5,DCAF4,EDRF1,NOS1AP,VPS13B,FGF1,FGFR1,NSG1,GNAL,PCLO,SHISAL1,KCNJ3,KCNN2,AFDN,NFYA,NPR2,OPRL1,KCNK10,PDE4B,ENPP2,TMOD2,PLCD1,MAPK8,ZFHX4,KLHDC8A,WLS,PKNOX2,RGL1,TF,GPR161,SLC44A1,TRH,AMACR,TRPM2,OSBP2,CAMK1G" Drug 6925_UP "ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASPHD1,ASIC2,AP2A2,APBA2,GAS7,AQP4,SEMA4G,CFLAR,ST3GAL5,ARHGEF1,VAX2,DNAJB5,PDE4DIP,CTNND2,SNPH,GSDME,TMCC2,DTNA,FCF1,C3orf18,RASGRP2,RRAGB,INPP5K,SRCAP,GNG4,PRUNE2,KLF12,MBD1,NOVA2,MAPK7,PTN,RAD52,ZCWPW1,RGS10,EMID1,TRAPPC13,ZCCHC24,TSNAXIP1,IQSEC2,SS18,MAPK8IP3,STX1A,VPS13A,SYN2,EXOC7,WSCD1,TCF7L2,TK2,REEP1,KCNAB1" Drug 1525_DN Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ARID1A,AK2,GAS7,FAM131A,SLC4A4,BTRC,CBFA2T2,FOXN3,PLEKHB1,RAB28,SULT4A1,LRIG1,PDE4DIP,DCAF8,GIT2,SMG7,TMCC2,DTNA,CNNM1,RBM12,CDKL3,F3,B4GALNT1,ZNF276,SLC2A6,KCNJ3,MATK,NDUFA5,SLC25A23,PPP2R5C,NKAIN1,RAB3A,ZNF821,FBXO11,TMCC1,ELOVL4,PLCB1,ARC,FBXW11,KIAA0930,TCF7L2,AP4E1,TMOD1,KCTD2,ZMYND8,ZNF74,SPHK2,REEP1,FTSJ1,ST7" Drug 5019_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NME5,APBA2,PPFIA3,ASPH,CAMK2G,KRIT1,CBFA2T2,LHX2,RAB28,NECTIN3,EDRF1,INTS1,ZNF804A,MFAP3L,EFNA3,ENO2,TAOK3,FHL1,GAA,INPP5K,MSL3,GPR37,NR3C1,ARHGAP19,HSF2,IGSF1,IL6ST,MAP4,MATK,NF1,SLC11A2,SLC25A23,PMP22,LRP12,PPP2R2B,PTPA,ARHGEF10L,SBF1,SH3BP2,CPEB3,SLC1A7,EPN2,SMTN,SCMH1,SLN,CDK5RAP2,SS18,TRIM2,CRTC1,HPS4" Drug 1272_DN Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADORA2A,MRTFA,PPFIA4,APP,ARRB2,NCOA1,C5,OSGIN2,CBR1,HOMER3,SEC31B,MAML1,CTIF,DBN1,SMG7,DTNA,EEF1A2,FCGRT,FGFR1,SEMA4D,POMT1,MPP6,HTATSF1,STON1,ITGAM,ITPKB,ZNF862,NEFH,NRGN,NUCB1,ODF2,PDE3B,ARHGEF10L,PAQR6,DGLUCY,SLC6A8,MAPKBP1,KDM4B,WDTC1,ZCCHC24,SPTAN1,MAPK8IP3,SUPT5H,TBL1X,SLC44A1,TNS1,UBTF,ATP6V0E2,PRDM2,SMIM8" Drug 2727_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADORA1,APBB2,PPFIA3,ALDH4A1,CCDC181,BMP7,BTRC,CACNB4,CACNA2D2,STOML1,NCOR2,DAPK3,DBT,DMPK,DRD1,EDIL3,DLC1,HPCAL4,CSPG5,GFRA2,STMN2,HPSE2,SYNPO,KCND3,KIF5A,DDX25,NOS1,NTRK2,OXTR,PCSK2,PDE1C,LRRN3,CEP41,SYNDIG1,RPH3A,PKNOX2,SNCA,DOK5,SOX15,PEG10,IQSEC2,PLCB1,ASTN2,IQCE,FAM189A1,SLC19A3,BEST1,SPHK2,SLC17A7,NUP214" Drug 5393_DN Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "RALGAPA1,APLP1,GYG2,CFAP410,HAP1,ADGRG1,CHM,TAOK2,LHX2,SH2B1,PDE4DIP,MAML1,EFNA3,SH3GLB1,MBNL2,ZNF589,EFCAB2,FAM49B,SEPT9,INPP5K,GCNT2,GNG4,SPACA9,ATXN2L,ICA1,INPP5B,KCNH2,LSS,MGAT3,MIA2,ADAM22,NPTX1,PDE3B,CCSER2,NLE1,PLEC,PLXNB1,PRKAR1B,TMEM104,ELOVL2,RGS12,SH3BP2,SMARCA4,ZCCHC24,EMC1,SPTAN1,TRIM2,PSD3,VAV2,GDPD5" Drug 3711_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ADCY6,PKP4,APC,GAS7,SLC4A4,ATP2A2,C5,IL33,BTRC,RAB28,PICK1,ARHGAP24,TOX,MAML1,DAPK3,PLPPR4,TMCC2,ACOT8,OPTN,EFNA3,EFNB3,TUBD1,SCML2,FGFR1,CINP,GLYR1,GPM6B,EML4,MT1M,NUMA1,CCSER2,MAPK7,SAMD9,FAM120C,ZDHHC14,KCTD17,OGDHL,ARHGAP26,SPTB,SYNE1,TMPO,TNS1,TPM2,TRIO,REEP1,UPF3A,WNK1,GDPD5,VPS35L" Drug 6446_UP Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,NR0B1,ALCAM,BEGAIN,KCNAB2,APOC1,PPP4R4,PDE8B,ASPH,BRINP2,CFAP410,CACNA1D,CLGN,CHRNA4,SULT4A1,HOMER3,CPS1,ARHGEF10,PHYHIP,MFAP3L,SGK2,EGR3,LRRC23,RASGRP2,GAP43,SIGLEC8,GFER,GNAO1,GPR22,ICA1,IRF8,JAK2,KCNJ4,MAPT,ADAM22,SMOX,SLC25A23,LRP12,PPP5C,MAPK7,RET,SYBU,SLC11A1,PEG10,MAPK8IP3,POPDC3,PCDHA6,RIMBP2,AMOT,FAM13C" Drug 4717_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABHD6,ALK,SYT13,LGR5,PDE8B,SCAPER,CCKBR,QKI,FAM149A,CREM,SPOCK2,GIT2,EFNB3,EZH1,FGF12,KHDRBS3,GAD1,GCNT2,RUNDC3A,GNAS,GPM6B,TDRKH,CACFD1,GRM7,GRM8,HLF,MEF2C,MID1,NEFM,PDE4B,GPR85,STRN3,PPP5C,ELOVL2,C1orf54,RBBP6,SYBU,NLGN1,DZIP1,SNCA,SOX10,ZC3H13,PLCB1,SYT5,PCDHA6,SEZ6L,OSBP2,VAV2,SCG2,CAMK1G" Drug 5399_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,ARID1A,PLA2G6,C1QTNF1,MRTFA,CDC14B,ASPH,CDK5R1,SRSF11,COL9A3,DCC,GSDME,DMPK,DSCAM,EDNRA,RRAGB,FHL1,HBS1L,TMEM8B,GPM6B,NR3C1,HPSE2,ITPKB,JAK2,KIF5A,MAP4,NDUFA5,NF1,NNAT,NOS1,CNOT4,PDE3B,PLCD1,MAPK8,GRAMD1C,C1orf54,SH3BP2,FBXO11,LIMCH1,SP4,SAMSN1,PLCB1,ROBO3,MCF2L,ZEB1,PCDHGB6,UBE3A,SYNC,KCNAB1,SENP7" Drug 7257_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "BIN1,APC,MAP7,ZFYVE9,PICK1,CSF1,GIT2,RUSC2,KLHL3,FEM1B,STX2,BAIAP2,GAD2,COPS8,GLRB,KIF5C,LIG4,VWA5A,MBD1,NF1,NOVA2,NUMA1,PALM,PEX5,RAB3IL1,ZCWPW1,RGS4,TTLL7,PPP1R9A,AMBRA1,PPP4R3A,MYH15,ARHGAP26,SPTAN1,SPTB,SPART,CEP68,SYT1,ATP11A,WWC1,TRIM2,ZNF34,R3HDM1,TRPC1,ZMYND8,XRCC4,TFIP11,EMSY,KAT6A,RNF170" Drug 3018_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABAT,ADGRF5,BIN1,CDC42BPA,AQP4,ASPH,ATP2B3,CACNA1I,MAP7,MTMR7,DLGAP1,SLC4A8,RGS6,SUSD5,DZIP3,INTS1,MAGI2,ARNT2,EXOG,ATN1,OPTN,PRELID3A,SIGLEC8,INPP5K,ADAM28,GPM6B,GPR37,HPSE2,HNMT,HTR2A,MAG,NCAM1,NPY,OMG,CLDN11,PCDH9,PMP2,FSD1,BCAS3,ZSCAN32,SLC11A1,ZNF423,CDK19,ARHGEF9,SYT1,TACR1,AP4E1,RUNDC3B,FLRT2,ZNF225" Drug 2256_DN Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG2,LTBP4,MRTFA,BIN1,ALDH4A1,CFLAR,CAMK2G,SPAG9,CCNT1,CACNA2D2,DAPK3,DSCAM,PLXNC1,DMTN,LRRC23,SRCAP,TXNL4A,SPIN1,POLL,GNG4,GRIK5,IL6ST,ITPKB,KCNJ3,VWA5A,MAP4,MIA2,ZNF862,NF1,NUMA1,PCDH9,PIK3R1,FAM120C,RAB3A,MSANTD2,SLC25A36,GSTCD,SBF1,ZNF821,RBM34,CDK19,TBL1X,CRTC1,ZBTB14,SLC30A3,WNK1,PRDM2,SEMA3B,PHTF2,SSPN" Drug 3848_DN Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ACTN2,PLA2G6,MRTFA,CDC42BPA,APC,PLA2G4C,CDK13,DNAH17,MARK4,SLC4A4,AKAP7,RIMS2,DCAF4,CELSR3,MBNL2,ELN,CGREF1,SRCAP,GFER,GRIK5,ICA1,MIA2,MYO7A,ZNF862,NF1,PCDH9,PDPK1,PLCD1,PPP5C,RELN,SNRK,PTHLH,RAB3A,RAB3IL1,ZDHHC14,ASAP3,SMARCD3,MAPK8IP3,SYN2,KIAA1107,ZNF34,THRA,HEY2,TMOD1,FAM155A,PLPPR2,VIPR2,LAT2,REEP1,KCNAB1" Drug 5963_UP H-7 dihydrochloride; Up 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ABHD6,NDRG2,ADD2,CDC42BPA,APP,SLC4A4,KSR1,CACNA1I,BAIAP3,LDLRAD4,CAMK2B,RHBDL1,INA,CHRNA4,CLCN4,ARHGEF6,ATRNL1,RIMS3,DRD1,DTNA,HSD17B14,DMTN,ATP8A1,GABRA2,GPM6B,LPAR4,GUCY1A1,HRH3,HLF,IRF8,ITIH2,KCNMA1,LSS,NEFH,NNAT,PALM,CAMKV,NECAB2,SAMD9,PTPRH,S100B,FBXO11,CXXC4,SOX2,ROBO3,DOCK9,WIPF1,SLC17A7,ITM2C,PLSCR4" Drug 434_UP sodium 4-phenylbutyrate; Up 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADD2,ADORA2A,PROM1,CACNA1I,RAB29,CDH10,CHM,CHN2,CNTNAP2,PLPPR4,SRGAP3,DRP2,EXTL2,FGF1,DPYSL4,POMT1,FAM49B,GABRA5,DISC1,GRIN1,PTPRT,DIPK1A,KCNJ5,KHK,MBP,NOS1,PFKFB4,RETREG1,RC3H2,LRRN3,PTPRN,RAB3A,RASGRF1,GAL3ST4,GSTCD,ZFP30,SH3BP2,ASAP3,NPAS3,SPART,TCF4,KIAA0930,GPR161,TNS1,SEZ6L,LAT2,SLC13A3,SLC26A10,GDPD5,MVB12B" Drug 5520_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADD2,BEGAIN,ANK1,ANK3,CDK10,ATP6V0A1,CFAP410,CAMK2B,CLTB,QKI,SULT4A1,CSF1,RIMS2,EDRF1,DRD1,DYRK1A,NRN1,F5,OLFM1,C1orf61,AFF2,GAD2,RUNDC3A,GPM6B,GRIK5,DHX35,ITIH2,KCND3,LRP1B,PCBP3,CLDN11,CDK14,MINDY2,PTAFR,PTCH1,RYR3,SCN8A,ST6GAL1,RPH3A,PKNOX2,PDZD2,WDTC1,HECW1,KIAA0930,TMOD1,CABIN1,VAV2,KCNK12,SPHK2,WNK1" Drug 4623_UP Hymecromone [90-33-5]; Up 200; 22.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADCY6,PLA2G6,ADGRF5,GAS7,AQP4,BRINP2,N4BP2L1,CACNA1G,HAP1,ENTPD2,ADGRG1,SOCS6,TAOK2,RAB26,LRIG1,GREB1,CNIH3,MFAP3L,DMPK,SGK2,SIDT2,EPHA5,CSPG5,FYB1,SPACA9,GRM8,AP4S1,ELOVL5,HNMT,KIF5C,TAGLN3,NCAM1,FA2H,ENOX1,GSTCD,SYNDIG1,ZFP2,KANSL3,ARHGAP26,MAPK8IP3,PHLDB1,SYN2,KIAA1107,TCF7,TEX15,RPRM,FLRT2,WNK1,GJC2,DPF3" Drug 202_DN raloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ADORA2A,PPFIA1,ASPA,CADM3,SYNJ2,WASF1,CALB2,KALRN,INA,CBFA2T2,SCARB1,NEURL1,CHGA,STOML1,LY86,NCOR2,GREB1,RIMS3,KIAA0586,DLG3,ATN1,SRPK3,PLEKHO1,ERCC2,OLFM1,GFRA1,RUNDC3A,ARHGAP19,SYNPO,AFF1,NF1,NPY,NTRK3,PLCD1,BSDC1,ZFHX4,RPS6KA2,SNCA,TMCC1,ZSWIM8,ZC3H13,SPTB,ST5,PHLDB1,COBL,EXOC7,SEZ6L,FLRT1,SLC26A10,SLC17A7" Drug 3396_UP Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "RALGAPA1,ADORA2A,KIAA1324,SEMA6A,MRTFA,APC,ALDH7A1,N4BP2L1,HIP1R,CBFA2T2,CHM,AKAP6,VCAN,SEC14L5,RASSF2,DAPK3,DYRK1A,TUBB4A,CAMKK2,FYB1,GAP43,MSL3,GPER1,GPR37,INPP5B,KIF5A,L1CAM,LMO2,CNOT4,NPR2,FXYD1,CEP41,PTAFR,KLHDC8A,WLS,RYR1,SLC11A1,CXXC4,TSNAXIP1,ZC3H13,PLCB1,TCF7L2,ZEB1,SPX,HEY2,TRPM2,ZMYND8,UGT8,PHTF2,SENP7" Drug 6031_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,AP2A2,C1QTNF3,APBB2,CDC14B,CDK10,CAPRIN2,ALDH4A1,USP2,CBFA2T2,CRLF1,SLIT2,NMT2,VCAN,GREB1,RASSF2,TMCC2,SIDT2,EFNB3,KAT8,FGF12,FGFR1,DISC1,SRCAP,GLYR1,POLL,GRIK5,INPP5B,SMAD1,ADAM22,RETREG1,PLXNB1,PPP5C,GON4L,RAD52,RGS10,RPS6KA2,PAQR6,SEMA6D,ASAP3,SLC6A8,SHANK2,EMC1,PHLDB1,TACC1,CRTC1,CHST8,TK2,TPD52,ZNF45" Drug 6801_UP Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "NDRG3,ADCY6,AMT,DNAH17,ASPA,ALDH4A1,CACNA1I,NFS1,FADS2,VAX2,SMARCAL1,CREM,CRMP1,AATK,MICAL2,PDE4DIP,JAKMIP2,EDNRA,PHC2,EFNA3,MRNIP,GPM6B,LPAR4,GPER1,CACFD1,TJAP1,KCNMA1,MMP16,ZNF862,NTRK2,PIK3CD,PLCD1,SLC25A23,PPP5C,LRRC49,EMID1,RASA3,PPP1R9A,ZSWIM8,EMC1,IQSEC2,TSPYL2,VPS13A,PSD3,ZNF34,TNS1,LAT2,ZNF24,PRDM2,TIGD6" Drug 4551_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "APBB2,ARNTL,MYRF,BAIAP3,RAB28,NRXN3,DNAJB5,AATK,CSNK1E,PDE4DIP,MFAP3L,SGSM2,CHRDL1,EXOG,EDIL3,EDNRA,PLXNC1,AASS,TNK2,MRNIP,PNMA2,DENND2A,SRCAP,MSL3,GRK4,TJAP1,MAPT,MX1,NF1,CNOT4,SLC11A2,PLXNB1,POLG,RAB3IL1,DCUN1D2,RPS6KA2,MYH15,SPTAN1,ASTN2,ATP11A,SYNE1,TIAM1,TK2,AMACR,HIRA,PLPPR2,MICAL1,XRCC4,ZNF711,SPHK2" Drug 4447_DN nordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,PLA2G6,C1QTNF1,C1QTNF3,PPFIA3,PPP4R4,MARK4,ALDH4A1,SLC4A4,ADGRB2,CDK5R1,BTRC,CBFA2T2,ARHGAP33,TAOK2,CREM,KBTBD11,OPTN,ING4,SPEG,F3,FGFR1,SCARA3,POMT1,DENND2A,INPP5K,GPM6B,TDRKH,IL12A,INPP5B,MAPT,KITLG,MX1,MINDY2,BCAS3,PID1,ZNF821,ASAP3,SIRT2,MYH15,TMCC1,WDTC1,RAP1GAP2,COBL,ZEB1,TMPO,UBE3A,XRCC4,EPM2A,PHTF2" Drug 3581_DN Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "ASIC1,GAS7,PPFIA3,SHROOM2,CDC14B,PPP4R4,ARRB1,MARK4,SLC4A4,ALDH7A1,LDLRAD4,SULT4A1,AKAP7,ABI3BP,SH2B1,GREB1,NOS1AP,LYPD1,EDNRA,EFNB3,ING4,ACSL4,SCML2,SCARA3,ICA1,INPP1,KCNN2,LMO2,CNOT4,CCSER2,RAD52,GTDC1,ROM1,TCP11L1,EMID1,SH3BP2,NLGN1,SLC6A8,LIMCH1,WDTC1,ZCCHC24,KDM4C,ZNF423,SPTAN1,ZNF34,ZKSCAN5,XRCC4,REEP1,PRDM2,GDPD5" Drug 5827_UP Mifepristone [84371-65-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.44E-04 1.00E+00 2.92E-03 3.33E-02 50 198 "MRTFA,SEMA7A,CNTNAP1,SEMA4G,SLC4A4,ATP2B3,KIF1A,MYRF,BAIAP3,CACNG1,CDC42,CACNA2D2,CHI3L2,JAM2,NRXN3,RAB26,IQCK,SNPH,FCF1,KAT8,FER,TRMO,CGREF1,GLRB,GNG3,KCNB1,KIF5C,KIFC3,GIT1,PALM,SERPINI1,PPP2R2B,DCHS2,GON4L,RFX2,RGS12,TMEM206,FBXW7,RYR3,SUPT20H,BCAN,CCDC88A,LIMCH1,TMCC1,ZBTB43,TIMP4,BEX4,TRO,TFIP11,KCNAB1" Drug ctd:C012301 domoic acid CTD 3.52E-04 1.00E+00 2.99E-03 3.40E-02 26 84 "WDR35,CADM3,SLC25A14,CHGA,CST3,IST1,ARNT2,PDCD6IP,OLIG2,ACSL4,ERGIC3,NFU1,GLDC,GRIA1,HMGCL,JAK1,NPPA,PFKFB3,PTPN13,EFHD1,ANKRD12,TMEM9,CBX5,RBFOX2,SF1,NDRG4" Drug CID000005018 SCH 23390 Stitch 3.57E-04 1.00E+00 3.03E-03 3.45E-02 33 116 "ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1B,ADRB2,CCK,LRBA,CHRM1,CNR1,DRD1,EEF1A2,PPP1R1B,GAD1,GAD2,ARPP21,GPT2,GRIA1,GRIK1,GRIN2C,GRIN2D,HRH3,HTR2A,HTR5A,NPY,OPRL1,PDYN,PENK,PRKACB,RGS3,SOX10,TAC1,MLST8" Drug CID000001104 "(2S,3R)-Sphingosine" Stitch 3.57E-04 1.00E+00 3.03E-03 3.45E-02 87 390 "ACTN1,PLA2G6,ANK1,DGKZ,DGKD,PDXK,PLA2G4C,CALM1,CERS5,DGKI,LRBA,CDC42,SOCS6,CHN1,CHRM1,CHRNA4,CHRNB2,CLTB,GAL3ST1,PLCXD3,CYBB,BOC,DGKB,DGKG,GIT2,EGFR,ERBB4,PTK2B,ACTL6B,GALC,NEU3,GCNT2,GPT2,GPR12,PLCD4,GPR45,TNFAIP8L3,MYLK2,IGF1,ITGAM,KCNN2,ASPRV1,NEUROD2,ENPP2,GPR85,PENK,PLCB2,PLCD1,TRHDE,FA2H,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,PTK2,PBRM1,ACER3,RYR1,RYR3,MAPK12,SMPD3,SELL,IFT122,ST5,PLCB1,SYT1,ALG1,TIAM1,ACTR6,TPD52L2,WBP2,TRH,ZMYND8,TTPA,UGT8,SPHK2,FTSJ1,PLPPR5,PLD4,CERS6" Drug CID000004843 piracetam Stitch 3.58E-04 1.00E+00 3.04E-03 3.46E-02 15 38 "ABAT,ACHE,BCHE,CBS,CS,CST3,GPHN,GABRA1,GABRG2,GFAP,GLRB,POLL,SCN2A,ARHGEF9,EPM2A" Drug CID000003184 E 4031 Stitch 3.59E-04 1.00E+00 3.05E-03 3.47E-02 19 54 "HCN2,AASS,KCNA1,KCNA2,KCNA6,KCNB1,KCNC1,KCND1,KCND3,KCNH1,KCNH2,KCNJ3,KCNMA1,KCNQ2,KCNQ3,ENPP2,PTPRN2,TRH,KCNAB1" Drug ctd:C028451 "3,4,3',4'-tetrachlorobiphenyl" CTD 3.63E-04 1.00E+00 3.08E-03 3.51E-02 100 460 "SERPINA3,ACADM,ABHD6,ADCY6,AGT,OSBPL1A,AK2,BBOX1,AQP4,PDXK,N4BP2L1,ST3GAL5,C5,CA8,RHBDL1,USP2,CHN2,CLU,NGEF,FAM189A2,QKI,CNN3,BTF3L4,CRY2,GDA,FEZ2,PDE4DIP,PHF14,PITPNC1,RHOBTB1,RABGAP1L,FAM107B,NR1D2,SLC12A6,GNE,DNAJB6,GPR61,EIF1,EPB41,F5,FCGRT,FECH,FGF1,ILDR2,IQGAP2,DHRS4,GLI2,GPT2,GSTT2,FAM107A,HLF,HNRNPK,IDH3A,IL6R,KCNN2,IPO5,SMAD9,GPR155,MAOB,AQP11,MIA2,NFE2L2,NFIX,LRIT2,NPR2,SETD4,P2RY1,PAH,ENPP2,ABCB1,PIK3R1,PPARA,PPP2R5E,MAPK3,MASP1,APTX,ACSM5,ATG16L1,ZYG11B,KLHL11,CLIP1,RXRA,FNIP1,FAM102A,SLC1A2,PEX26,SLC6A9,LMBRD1,KDM4B,ERC1,SULF2,ANKRD28,ANKRD12,DOCK9,ENHO,UBTF,DNAJC12,AMN1,TTC7A,IFT88" Drug CID000007464 4-isopropylaniline Stitch 3.65E-04 1.00E+00 3.10E-03 3.52E-02 23 71 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,AGT,ALAD,BCHE,LRBA,CHRM1,NR1D2,ADGRV1,GNAS,KCNA2,KCNA4,KCNB1,KCND2,NPPA,PPP3CC,PRKACB,PRKCB,RORB" Drug CID000001218 SKF 81297 Stitch 3.70E-04 1.00E+00 3.14E-03 3.58E-02 16 42 "ABAT,ADORA2A,SLC32A1,DRD1,PPP1R1B,GAD1,GNAS,GRIA1,GRIA2,GRIA4,GRIK1,GRM3,HRH3,PDCD2,PDYN,ALG1" Drug CID000005641 urethane Stitch 3.75E-04 1.00E+00 3.18E-03 3.62E-02 44 169 "ADRA1D,ADRA1B,ADRB2,AGT,CCK,CCKBR,CHRM1,SULT4A1,BOC,DCC,DMPK,EDN1,EDN3,VPS26C,B3GAT1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,INPP5K,CRCP,GLRB,GRIK1,GRIN2C,GRIN2D,BCO1,NOS1,NPY,OPRL1,PDYN,PENK,KHDRBS2,ZNF365,SST,SSTR2,TAC1,TAC3,TACR1,TRH,TSC1,WRN,PORCN" Drug CID000001986 acetazolamide Stitch 3.75E-04 1.00E+00 3.18E-03 3.62E-02 31 107 "BRAP,APOC1,SLC4A4,ATP2A2,CA4,CA8,CA12,CACNA1A,CACNA2D1,NGB,SLC22A6,SLC4A7,SLC4A8,CTNND1,DMPK,NR1D2,DMTN,F3,CELF1,GLS,HBA1,KCNA1,KCNA2,KCNA4,KCNA6,KCNK1,KCNK2,PTCH1,RBFOX2,CA14,HPS4" Drug CID000166931 phosphine oxide Stitch 3.75E-04 1.00E+00 3.18E-03 3.62E-02 31 107 "LRBA,CHN1,AKAP6,DBI,GJB1,KCNMB4,GRM7,KCNC1,KCNJ3,KCNJ10,KCNMA1,KCNQ2,MAG,MBP,MOBP,MOG,NBL1,OMG,PC,PMP22,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,ROM1,RPS20,RYR1,RYR3,KIF1B,MLC1" Drug 7136_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.80E-04 1.00E+00 3.22E-03 3.66E-02 45 174 "MTUS1,MARCH3,MARK4,ALDH4A1,ST3GAL5,HIP1R,NRXN3,ARMC8,CREB5,ABCG1,CTH,KIAA0513,RIMS3,C2CD2L,CDON,ATN1,EFNA3,SORBS3,EXTL2,TUBB4A,ATP8A1,BAIAP2,FYN,AHDC1,GLS,GUCY1B1,BACH2,KIF5C,MAPT,NRGN,PFKFB2,SERPINI1,PIK3CD,RGS4,SH3GL3,FAM214B,TNIK,ARHGAP26,IQSEC2,ELOVL4,RGL1,SYT1,ZMAT3,DNAJC12,WNT7A" Drug CID005287911 coformycin 5'-phosphate Stitch 3.81E-04 1.00E+00 3.23E-03 3.68E-02 12 27 "BRAP,AMPD2,AMPD3,AQP4,BCS1L,LGI1,F3,F5,ADAM22,NCF2,PPP1R1A,NUDT11" Drug CID000220531 mAHP Stitch 3.81E-04 1.00E+00 3.23E-03 3.68E-02 12 27 "CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,INA,CHRM1,GRM1,GRM5,KCNN3,OXTR,PTPRN2" Drug 2928_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.83E-04 1.00E+00 3.24E-03 3.69E-02 46 179 "ABHD6,ADORA3,BIN1,ANK3,CLCN4,SIPA1L1,SEC14L5,RCAN1,FAM13A,ANKMY1,EYA1,F3,TUBB4A,ST3GAL6,OLFM1,FGR,GLUL,GRIK5,GSN,SCRG1,IL6ST,ITPKA,MOBP,MSR1,NAP1L2,NINJ2,NPTX1,TREM2,PFKFB4,CDK14,PGAM2,MARCH1,GTDC1,CPEB3,KDM4B,ZHX3,SPTAN1,SAMSN1,KANK1,TBL1X,SZT2,TMOD1,RPRM,LMF1,SLC13A3,ZBTB16" Drug 1005_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.83E-04 1.00E+00 3.24E-03 3.69E-02 46 179 "OSBPL1A,BIN1,OGT,CFLAR,ST3GAL5,CAMK2G,PDE4DIP,GIT2,ARMCX2,RCAN1,DTNA,TOM1,FHL1,HBS1L,B4GALNT1,DIDO1,CACFD1,HLF,KCNN1,MPP2,NACA,NAP1L2,NDUFA5,NPR2,NUCB2,MORC4,ROM1,HSPA4L,SGK1,SH3BGR,ITSN1,PPM1E,TSPYL2,POGZ,JMJD6,ATP11A,EXOC7,TRIM2,BHLHB9,WBP2,TRPC1,DNAJC12,VLDLR,ZNF74,PHTF2,FXR1" Drug CID004488326 Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol Stitch 3.85E-04 1.00E+00 3.24E-03 3.69E-02 25 80 "ADCY2,ADCY5,ADCY6,ADCY8,AP1B1,CACNA1B,CACNA1E,CALM1,CCK,CNR1,DNM2,DRD1,DMTN,KCNJ3,NME4,NPY,OPRL1,PDYN,PENK,MAPK8,RGS4,RIT2,SST,TAC1,TACR1" Drug 1737_UP Prenylamine lactate [69-43-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.86E-04 1.00E+00 3.24E-03 3.69E-02 47 184 "NDRG2,ARNTL,CADM3,ARHGEF7,CANX,UBE2L6,SEC31B,CSNK1G3,DOCK4,BRINP1,HP1BP3,KLHL3,SMG7,EFNB3,MBNL2,PLEKHO1,OGA,INPP5K,GLS,GLUL,IFI16,ITGA7,KCNN1,IPO5,MT1M,MX1,NF1,CNOT4,ENPP2,CCSER2,PLEC,SAMD9,GON4L,ZSCAN32,SAFB,SGK1,ELMO2,SLC22A4,KDM4B,NXT2,TCF7L2,TMPO,R3HDM1,PARD3,ZNF24,UPF3A,NLRP3" Drug ctd:D005047 Etoposide CTD 3.88E-04 1.00E+00 3.24E-03 3.69E-02 124 592 "ACADM,MTUS1,NR0B1,ALAD,BIN1,APAF1,KCNAB2,APLP1,IGDCC4,ATM,ATP1A1,KIF1A,BCL2L2,BID,BLM,CFLAR,ST3GAL5,DDR1,CAST,MAP7,PRC1,ENTPD2,ZBED1,LHX2,NMT2,ABCG2,COL9A3,TBPL1,CPS1,CREM,AKAP12,VCAN,CTH,DCAF4,HDAC4,DBN1,DCT,ZBTB24,HEPH,DMD,RCAN1,EDN1,EDNRB,EGFR,CERCAM,BSCL2,EN2,ERBB2,ERBB4,EFS,F3,FDFT1,FHL1,FOXF2,FOXO3,FLNC,ATP13A4,DPYSL4,SORBS1,CGREF1,FYN,DKK3,CAB39,AHCYL1,MTHFD2,SESN1,PPARGC1A,DBF4,GPM6B,GPR37,STMN2,GSTT2,SLC2A6,WIF1,HSP90AA1,STMN1,MATN2,MBP,MXI1,MYCN,MYT1,NAP1L1,NFE2L2,IGSF11,OGG1,P2RX7,PDE2A,PDE4B,ABCB1,SERPINE2,GPSM2,PLP1,PMP2,PMP22,PRKCZ,MAPK3,RAD52,ROBO1,RTKN,RXRA,MAPK12,ATXN1,MRAS,ZNF365,LIMCH1,RBM34,SCN3B,SOX10,SPP1,EPB41L3,INKA2,COBL,ANKRD28,ROBO3,TBL1X,TRIM2,TP53BP1,WRN,XRCC4,ZNF32,ZNF45,CIAPIN1,PCBP4,ST7" Drug 4400_DN Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.88E-04 1.00E+00 3.24E-03 3.69E-02 48 189 "NDRG2,ALK,CNTNAP1,GAS7,CADM3,LDLRAD4,CAMK2B,NEURL1,ARHGEF2,FOXN3,RAB28,ZFYVE9,AKAP7,ABI3BP,TCEAL2,SPOCK2,RABGAP1L,DSCAM,DTNA,ERCC2,KHDRBS3,TMEM8B,GNAS,GNG4,GRM1,ICA1,KCNN1,KIT,MBD1,MSI1,NF1,NFYA,NTRK2,RETREG1,PRKAR1B,PLPPR1,MYH14,EMID1,BTBD7,SMARCD3,LIMCH1,KDM4B,CLSTN2,ROBO3,ZEB1,R3HDM1,HIRA,PRDM2" Drug 6170_DN retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.88E-04 1.00E+00 3.24E-03 3.69E-02 48 189 "ACTN2,FAM131A,APP,SEMA4G,PPP4R4,ALDH4A1,HIP1R,HOMER3,C2CD2,MICAL2,VCAN,NR1D2,ST8SIA3,ELN,OLIG2,FOXG1,CGREF1,GAA,GAB1,GABRA4,GSN,ATXN2L,ITGA7,MAP4,TM6SF1,SCAMP5,MX1,OMG,PLEC,PLP1,BCAS3,PTX3,TMEM231,PID1,MAP6D1,ST6GAL1,SLC1A3,EPN2,TMCC1,DDN,ANKRD28,KAZN,AP4E1,THRA,TNNT1,CDK20,REEP1,WNK1" Drug 2797_DN Seneciphylline [480-81-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.88E-04 1.00E+00 3.24E-03 3.69E-02 48 189 "ADD3,AP2A2,ALAD,APC,APOC1,APP,STX16,CFLAR,SPAG9,CCNT1,EPS15L1,QKI,AKAP7,ENTPD4,CSNK1E,SOCS5,TBC1D5,DAPK3,DNAJC6,LYPD1,EDNRA,FCF1,EPB41L1,EPB41L2,PDLIM5,ARFIP1,GLYR1,RAB30,HTATSF1,PCSK1N,MAP4K5,HSD17B1,HSF2,KCNJ3,MDM4,MSRA,ELOVL2,FBXO11,BTBD7,SEPT8,KANK1,PLCB1,FBXW11,TMPO,CDK20,ZNF24,GDPD5,PHTF2" Drug 836_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.88E-04 1.00E+00 3.24E-03 3.69E-02 48 189 "RALGAPA1,OSBPL1A,APC,EPB41L5,PPFIA3,CDC14B,SCARB1,TAOK2,ZFYVE9,FAM189A2,CREM,CRY2,DBT,OPTN,GRB10,NR3C1,LIG4,NAP1L2,OXTR,PIK3CD,RAB3IL1,MORC4,ATXN1,ZNF821,SFPQ,HSPA4L,SH3BGR,PPM1E,ASAP3,SLC20A2,ZKSCAN3,SMARCC2,LIMCH1,ZBTB43,TSPYL2,DIP2A,PHLDB1,JMJD6,EXOC7,TCF7L2,AHCYL2,PARD3,ZMYND8,ZKSCAN5,VLDLR,ZNF189,ST7,FXR1" Drug 3231_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.88E-04 1.00E+00 3.24E-03 3.69E-02 48 189 "NDRG2,NME5,APOC1,CDK13,ADGRB3,CALB2,HIP1R,CD86,TPP1,WHRN,NRG2,HAPLN1,VCAN,RIMS2,RIMS3,SPOCK2,ATN1,EFNB3,EXTL1,FGFR1,PRELID3A,SRCAP,RND1,GLS,GNG3,TDRKH,GRB10,GRM1,GUCY1A1,IL6ST,ITIH2,KCNJ5,NPTX1,SNTG1,LRP12,POU3F4,PPARA,PPP5C,MAPK7,GDPD2,TCP11L1,RPS6KA2,ATXN1,PEX26,ATP10B,TBCEL,WSCD1,TRIM2" Drug 5914_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "AP2A2,OSBPL1A,AMPD3,APOC1,MARK4,ATP6V0A1,CLU,TPP1,QKI,NECTIN3,SDC3,RIMS2,EDRF1,SEC14L5,RASSF2,DTNB,EFNA3,MBNL2,ING4,SORBS1,HBS1L,DIDO1,KCNN1,MDM4,MX1,NAP1L2,MBOAT7,MAPK7,MAPK8,TTLL7,HSPA4L,SH3BGR,PPM1E,CPEB3,PREX2,ZKSCAN3,SPTB,RGL1,POPDC3,SEMA4A,TBCEL,ZEB1,ARHGEF12,TNS1,FLRT2,VGF,LAT2,SLC17A7,SSPN" Drug 4573_UP Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "PPP4R4,DNAH17,FUBP1,BAIAP3,BTRC,CCKBR,USP2,ARHGEF2,CDH10,CNTFR,CREM,SH2B1,CSF1,CNTNAP2,ARHGEF4,DMPK,DMTN,ETV1,REEP2,PTK2B,KAT8,KIAA1109,FGF1,FGFR1,FGFR3,FLT1,GNG3,GRIK2,GRIK5,KLF12,LIG4,MAN2A2,ADAM11,AFF1,NF1,NUMA1,PDGFRA,PIK3R1,RETREG1,MINDY2,RGR,RGS4,MCMBP,TSNAXIP1,SOX15,UNC5B,SLC44A1,CDK20,SLC17A7" Drug 4263_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ADCY6,CHN2,TAOK2,ARHGEF4,DCAF4,GPRASP1,DBT,PLPPR4,PARD6A,DLG3,DPH1,EFNA3,FAM13A,LPAR6,PLEKHO1,SPEG,ETV1,POLR1B,PNMA2,FYN,GLRB,PRRC2B,RNFT2,DIPK1A,ITPKB,JAK2,LIG4,NDP,PLCD1,STRN3,RC3H2,AP1AR,SH3BP2,PPP1R9A,SLC1A3,SLC4A3,PPP4R3A,CAND2,DIP2A,VAMP1,PLCB1,ANKRD12,WWC1,IQCE,TCF4,TRIO,WIPF1,ZNF189,PHTF2" Drug 3725_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "AP2A2,ADGRF5,PPFIA1,APOC1,APP,ADAM15,ADGRB2,CFLAR,MTMR2,BTRC,CANX,LARGE1,PLEKHB1,CPS1,CREB5,CTNND2,CNIH3,AK5,RCAN1,DTNA,EDNRA,FAM13A,ING4,VPS26C,FGF1,FOXG1,SEMA4D,GNAS,GPM6A,KPNA5,MARK1,ZNF862,NOS1,CNOT4,NPR2,ODF2,PIK3CD,PTCH1,PID1,ATXN1,MAPK8IP3,MLC1,ANKRD12,TMEM121,R3HDM1,TRIO,ZNF24,REEP1,SENP7" Drug 2086_DN Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ACTN1,OGT,APAF1,APOC1,APP,ARRB2,ASPH,ST3GAL5,CNOT8,ZFYVE9,CLCN3,VCAN,SDC3,PPP6R2,DBT,SIDT2,LPAR6,SPEG,TESK2,SCARA3,PDLIM5,INPP5K,ZNF276,GLRB,GLS,GPER1,FICD,GUCY1A1,ICA1,MBD1,NFYA,SLC11A2,NUCB1,KCTD15,PTPA,CNNM2,SYTL2,CCDC25,SH3BGR,ST6GAL1,BTBD7,ZKSCAN3,COA1,LIMCH1,NXT2,METTL3,NDRG4,PLSCR4,SMIM8" Drug 3280_DN Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "AP2A2,GAS7,MARCH3,BTRC,CACNA1D,B4GALT6,RAB28,ZFYVE9,PLAA,QKI,NECTIN3,CSF1R,SOCS5,SDC3,CTNND2,PPP6R2,DCAF4,DNAJC6,RBM12,OGA,GPD2,MUM1,GIT1,NPR2,NPTX1,LRP12,RIPOR1,RGS12,FBXW7,RPS6KA2,EMID1,WLS,CLIP1,FERMT1,FNDC3A,ZCCHC24,ZBTB43,CLASP2,THSD1,ANKRD12,TRIM2,AP4E1,TMOD1,TRIO,WIPF1,ZBTB14,ZNF24,KCNAB1,C12orf4" Drug 7000_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ASIC1,ADCY6,PLA2G6,DOC2A,APBB2,APLP1,ARRB1,MARK4,KYAT1,EPS15L1,TPP1,FEZ1,SGSM2,MED12,CDON,SIDT2,EFNB3,PHF20L1,EGR3,FAM198B,FHL1,DPYSL4,GPR153,INPP5K,GLYR1,GLS,HNMT,TJAP1,MAP4,MAPT,MBD1,MDM4,MMP16,ADAM22,ZSCAN32,PTPRE,FAM120C,GTDC1,ZFHX4,PAQR6,ZNF821,SH3BP2,SYBU,ELOVL4,WSCD1,THRA,ZMYND8,REEP1,NAV2" Drug 4083_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "PLA2G6,ANK1,APBB1,AQP4,ATP2B3,CADM3,BMP7,BAIAP3,ARHGEF2,VAX2,CNTN1,SEC31B,CSF1R,LRIG1,MICAL2,PDE4DIP,RASGRP2,CACNG2,FGFR3,GNG3,GNG4,SOX21,HNMT,C2orf72,IGF1,KCND3,KCNF1,AFDN,MMP16,NPTX1,NTRK2,PAK3,PLCD1,DCHS2,RGR,TMEM206,KCNIP2,ASIC4,ASAP3,NTNG1,SLCO1A2,SOX10,IZUMO4,ARC,COBL,SPX,TLR4,AMOT,KCNAB1" Drug 3043_UP Niacin [59-67-6]; Up 200; 32.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ACHE,ABHD6,ALK,ANK1,DDO,SEMA4G,PPP4R4,ALDH4A1,MPDZ,BMP7,BAIAP3,CACNG1,KALRN,CLGN,SULT4A1,RIMS2,SEC14L5,ZNF337,DSCAM,HIPK3,KCNMB2,FAM198B,RND1,GRIK2,HPSE2,HTR2A,KCND3,MBP,MYH3,MYO7A,PAH,PRKCZ,MAPK10,PTPRN2,GAL3ST4,CRTAC1,KCTD17,MYH14,KCNIP1,SLC11A1,SLCO1A2,TMCC1,DOK5,ACSBG1,TBCEL,TMOD1,ZBTB16,PLSCR4,CAMK1G" Drug 4310_UP Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "DDX3Y,SYNJ1,CACNA1I,CA12,NEURL1,ADGRG1,CSF1,RIMS3,CTIF,ATN1,DTNA,DTNB,ABCC9,SORBS3,HPCAL4,ATP8A2,PTGDR2,HTR2A,SHISAL1,ITGA7,KCNB1,KCNJ5,KIFC3,SMAD1,KITLG,ZNF862,NPTX2,NUCB1,PALM,CDK18,PRKCB,GAL3ST4,CRTAC1,RGR,ZNF671,SYNDIG1,NTNG1,SLC6A9,SLC15A2,WDTC1,VAMP1,SZT2,DOCK9,CRTC1,CA14,VAV1,VGF,ZIC3,MVB12B" Drug 1179_DN "ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "GRAMD1B,ADRB2,MTUS1,OSBPL1A,C1QTNF3,ZSCAN18,NUMB,ADAM23,CFLAR,SCAPER,LDLRAD4,THSD7A,TPP1,RUBCN,EDRF1,ZFYVE16,SPATA2,ENO2,ZNF589,FYB1,TXNL4A,MAP4K5,MEF2C,NUCB1,PIK3R1,PLEC,PLTP,PRKCZ,PTAFR,RAB3IL1,SEC14L1,GALNT10,SH3BP2,ZKSCAN3,WDTC1,SPATA7,ZSWIM8,CDK19,TCF7,TCF7L2,ARHGEF12,CABIN1,WBP2,ZBTB14,ZNF45,ZNF74,REEP1,MAP3K12,AAAS" Drug 4154_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "NDRG2,C1QTNF3,AMT,ALDH7A1,CA12,HAP1,CBFA2T2,CACNA2D2,FOXN3,RAB28,ZNF337,DBN1,HIPK3,EFNB3,PLXNC1,ZNF589,PRELID3A,KHDRBS3,SEPT9,SRCAP,GLS,HNMT,TJAP1,KCNQ3,VWA5A,MDM4,KITLG,CNOT4,SLC11A2,PTHLH,RAD52,SH3BP2,FNDC3A,SLC1A7,SHANK2,SNCA,ZCCHC24,POPDC3,ROBO3,TBCEL,CRTC1,KCTD2,PARD3,ZKSCAN5,VGF,MICAL1,WIPF1,CLDND1,SYNC" Drug 6385_UP 5707885; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "PLA2G4C,ATP6V0A1,ADAM15,ARHGAP33,RAB28,ARHGEF6,MFAP3L,SV2A,RCAN1,EFNA3,C3orf18,RCAN2,VPS26C,ZNF589,FGF12,GAB1,GATM,SRCAP,GLYR1,GNG4,GPD2,GPR22,GRIN1,NR3C1,GRM7,ICA1,INPP5B,KIF5C,LSS,KITLG,CD200,PLEC,C19orf57,PRKCB,PTAFR,PTPRO,ATG16L1,PPM1E,WDTC1,KIF21B,IZUMO4,ZC3H13,SZT2,PCDHGA10,PCDHGA1,PCDHA5,TRO,VLDLR,UBE3B" Drug 6628_UP Glimepiride [93479-97-1]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "C1QTNF1,EPB41L5,ASTN1,CCDC181,FUBP1,HAP1,CHI3L2,CHRNB2,CNTFR,CRY2,PLCH2,RABGAP1L,ECM2,DYRK1A,EDNRA,SGK2,HIPK3,SEMA3D,EFNA3,ZMYND10,KIAA1109,FGFR1,CAMSAP1,FLT1,ADAM28,PCDH17,GRIA1,GRIK1,KLF12,KITLG,NRCAM,OMG,PDE2A,SPATA6,MAPK10,ZSCAN32,PTPRB,KIRREL1,ASAP3,NTNG1,RBM34,COBL,EXOC7,PDLIM2,CRTC1,SLC44A1,ICAM5,VGF,KCNAB1" Drug 6794_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ALCAM,APC,EPB41L5,BCAS1,ATM,SLC4A4,ALDH7A1,CFLAR,GYG2,SLIT2,RCHY1,ENTPD4,PDE4DIP,MFAP3L,RABGAP1L,DSCAM,EDNRA,CDKL3,FGFR1,OGA,ZNF276,TXNL4A,MSL3,FERMT2,BTN2A1,MATK,GIT1,NEK1,NNAT,PDE3B,POLG,GTDC1,RGS3,RPS6KA2,SBF1,SH3BP2,FNDC3A,ZNF365,BTBD7,ZCCHC24,SPART,SS18,TTBK2,PHLDB1,TBL1X,KIAA0930,ARHGEF12,MAP3K12,PHTF2" Drug 4335_DN Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "MRTFA,APC,SEMA4G,ALDH4A1,ADAM23,ADGRB2,MYRF,BTRC,PICK1,CSNK1E,VCAN,DCAF8,ATN1,HIPK3,SORBS3,ERCC2,CDKL3,FGF1,C1orf61,SEPT9,SRCAP,AHDC1,ATXN2L,TJAP1,INPP5B,ITGA7,ITPKA,KCNN1,LYRM9,NF1,NTRK2,ODF2,SAMD9,WDR25,RALGDS,LIMS2,SLC9A5,BTBD7,MYH15,KDM4B,KAZN,CABIN1,TRIO,VIPR2,KLC2,SPHK2,KCNAB1,PHTF2,GAN" Drug 6223_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ARID1A,ALCAM,SRPX,AMH,DGKD,PLA2G4C,USP2,CACNA2D2,CHN2,CSF1R,MFAP3L,C2CD2L,DMPK,ST8SIA3,CNNM1,EFNB3,MBNL2,ING4,GAP43,IL6R,MAP4,PTOV1,NTRK2,OGDH,PALM,PPP2R2B,PRKAR1B,NKAIN1,RAB5B,RALGDS,NEK11,SMTN,SLC11A1,IQSEC2,ARC,MCF2L,ARHGEF12,GPR161,UBTF,MICAL1,LAT2,SF1,UPF3A,MAP3K12,GDPD5,WIPF2,MVB12B,KAT6A,TIGD6" Drug 2430_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ABHD6,KIDINS220,AK2,PKP4,APAF1,APBB2,APC,ATM,SLC4A4,C5,MYRF,LDLRAD4,CACNA1A,MAP7,CLCN4,TMEM184B,ENTPD4,VCAN,DOCK4,SPATA2,TUBD1,FGFR1,FOXG1,GABRA2,ALDH1L1,SRCAP,AHDC1,CRCP,ITGAM,MAP4,CNOT4,NUMA1,MBOAT7,GON4L,ZNF493,SCG5,DOCK10,SMARCD3,EMC1,TSPYL2,RBM26,TROVE2,EXOC7,TCF7,THRA,RBFOX2,ZMYND8,MAP3K12,GDPD5" Drug 4838_UP Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "DPF1,ACLY,ADD3,KIDINS220,NME5,AMPD3,APC,APP,ADAM15,PLEKHB1,QKI,HOMER3,ENTPD4,CRY2,CTNND2,ZNF337,RIMS3,KIAA0586,DCTN1,SLC12A6,EFNA3,SPEG,RRAGB,AGAP2,IQCG,TJAP1,KCNJ3,KHK,LSS,NFYA,NPTX1,OCRL,POLR2F,PRKAR1B,MAPK7,TCP11L1,SAFB,ELMO2,SMARCA4,THSD1,INKA2,CEP68,ARHGEF9,OBSL1,TEX15,PARD3,SSBP2,UBTF,NSD2" Drug 4798_UP Propantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "AK2,KCNAB2,APC,SEMA4G,BRINP2,ATM,RIPK1,CFLAR,BTRC,CFAP410,CAMK2B,ZMYM4,RAB33A,COL9A3,NECTIN3,PUM1,DBN1,DMPK,TRAPPC9,DTNA,EDNRB,SIDT2,ENO2,DLC1,ZNF589,BAIAP2,PDLIM5,GABRA2,RASSF8,KCNH2,KCNMA1,NF1,NPR2,SLC25A23,LRRN3,MRAS,FRMPD1,PPP4R3A,BTBD7,ZHX3,ZBTB43,COLGALT2,SS18,FCHO1,EXOC7,SMG6,WSCD1,ARHGEF12,ZMYND8" Drug 4411_DN Cyclosporin A [59865-13-3]; Down 200; 3.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ALCAM,APBB2,PDE8B,MARK4,NCOA1,ST3GAL5,SLIT2,LHX2,RAB26,SH2B1,AKAP12,RIMS2,DBN1,MFAP3L,DNM1,EFNA3,HSD17B14,FGF13,BAIAP2,DISC1,C1QL1,GPR19,PCLO,BRINP3,KCNN1,KHK,MAN2A2,MMP16,MOBP,ADAM22,NF1,PDE3B,RIPOR1,RGS12,CEP68,PHLDB1,AJAP1,ATP11A,WSCD1,DMXL2,ZNF34,HIRA,FLRT2,ZIC3,ZNF74,EMSY,PRDM2,MVB12B,KAT6A" Drug 7164_UP Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "MRTFA,APBA2,PLA2G4C,ASPH,ALDH4A1,RGS9,BCL7A,SYNJ2,SCAPER,MTMR3,CACNB4,ARHGEF2,PLAA,CLCN3,NCOR2,EGFR,ING4,DMTN,ANKMY1,DLC1,FECH,BAIAP2,CGREF1,FYB1,SRCAP,GRK4,NR3C1,BTN2A1,SLC2A6,INPP5B,KCND3,LIG4,MAP2,ADAM22,ZNF862,PIK3CD,MAPK8,RGS12,TCP11L1,SBF1,NLGN1,SNCA,FAIM2,EMC1,CLSTN2,TPD52,VIPR2,VLDLR,SSPN" Drug 1278_UP Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "PLA2G6,APAF1,CASK,STX16,CNOT8,SLC4A7,SLITRK5,ZFYVE16,DBT,SGSM2,RABGAP1L,RCAN1,DTNA,HIPK3,FRY,ZNF589,KIAA1109,FHL1,ANKFY1,OGA,GABRA2,GART,ARFIP1,LILRA2,TJAP1,KCNJ5,LSS,MEST,NFYA,SLC11A2,ST8SIA5,PURG,STRN3,PTAFR,RASA3,HSPA4L,PPM1E,FNDC3A,SLC2A5,PPP4R3A,SRPK2,TROVE2,NXT2,NSFL1C,ANKRD12,CAMSAP2,FBXW11,TK2,ACTR3B" Drug 4417_DN Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ADORA1,PLA2G6,FAM131A,PPP4R4,LDLRAD4,KYAT1,CBFA2T2,WHRN,SLC4A7,TCEAL2,CPS1,SEC14L5,RASSF2,MAML1,STX2,DENND4A,INPP5K,ALDH1L1,ICA1,ITIH2,KCNN1,KIF5C,MAN2A2,MAP4,TM6SF1,MOBP,ADAM22,CNOT4,PDE4A,PIK3CD,PLCD1,MTRF1L,MAPK7,PTHLH,RAD52,RGS12,FNDC3A,RPH3A,SLC1A7,TSNAXIP1,ROBO3,WSCD1,ZEB1,PCDHGA10,SLC44A1,R3HDM1,HIRA,VIPR2,EMSY" Drug 3855_UP 0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "NDRG2,ADD2,APAF1,PRX,PLA2G4C,STX16,CACNA1D,CACNB2,NEURL1,CDH18,WHRN,CRY2,NCOR2,SNCAIP,DAPK3,NR1D2,ATN1,AGAP2,FUT9,SRCAP,C1QL1,SPIN1,STON1,GPER1,GSN,HLF,IL6ST,KCNJ3,LSS,KITLG,AFDN,MMP16,ADAM22,NEK1,NUMA1,PCDHGC3,PCDH9,GRAMD1C,RGS12,SOX2,ZCCHC24,ZBTB43,ATP11A,DOCK9,TMOD1,RBFOX2,RUNDC3B,VAV2,SENP7" Drug 1264_DN Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "PPFIA1,CDK13,NCOA1,EIF4G3,OSGIN2,CLCN3,SH2B1,OSBPL3,DCAF8,CTIF,RASGRP2,EZH1,KAT8,ZNF589,FGFR1,FYB1,ERAP1,SESN1,MUM1,AGBL5,KIF2A,NUCB1,PDE3B,GPSM2,PPP5C,SAMD9,PTCH1,RAB5B,GTDC1,RGS10,DGLUCY,ITSN1,RAB3GAP1,INTS9,ZCCHC24,CLASP2,STXBP1,PRRC2C,ARHGEF9,DDHD2,FAM208A,TCF4,TCF7,WDR7,KAT6B,TNS1,METTL3,ELP5,EVI5" Drug 2238_DN Pindolol [13523-86-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 49 194 "ASIC1,NDRG2,APC,EPB41L5,PLA2G4C,MARK4,ASPH,CFLAR,SYNJ2,GYG2,VAX2,SEC14L5,CTIF,ZNF589,FGFR1,FHL1,GAB1,SEPT9,MALT1,POLL,TJAP1,IGSF1,LMO2,VWA5A,MSI1,ADAM22,LYRM9,NUMA1,SERPINE2,CCSER2,PRKAR1B,PRPH,ZSCAN2,RGS10,RNASEL,SH3BGR,PEX26,SMARCD3,SNCA,RBM34,ARHGAP26,PLCB1,EXOC7,KIAA0930,RPGRIP1L,TNS2,TIAM1,TK2,BEX4" Drug 4659_UP Equilin [474-86-2]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SYN3,ADGRB2,CACNA2D1,MTMR7,NEURL1,DLGAP1,CHI3L2,DNAJB5,AKAP5,CRMP1,ARHGAP24,MYEF2,MFAP3L,C2CD2L,PLPPR4,SRGAP3,HS3ST2,TOM1,DYRK1A,MBNL2,SRPK3,MTSS1L,ERBB4,APC2,AGAP2,GAB1,SIGLEC8,NEU3,GLI2,GPR75,GNAL,GPM6B,GRM8,BACH2,ELOVL5,P2RX7,PDE4A,PPP2R2B,PROX1,PLPPR1,RFX2,RGS12,EMID1,NLGN1,KANSL3,SLC9A5,PCDHGB6,LILRA4,REEP1,KCNAB1" Drug 6020_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "C1QTNF3,LTBP4,BIN1,APC,PPFIA3,CFAP410,CA4,CAMK2G,KYAT1,CCKBR,CDH8,EPS15L1,CRY2,PDE4DIP,MAML1,TMCC2,EFNA3,EFNB3,ENO2,RASGRP2,PRELID3A,INPP5K,SRCAP,GRK4,NR3C1,GSTM5,NXPH3,ICA1,KPNA5,MEF2C,CDK18,PDE3B,PGAM2,GRAMD1C,PRPH,EMID1,SH3BP2,SLC20A2,WDTC1,EMC1,KDM4C,SPTB,CDK19,MAPK8IP3,TACC1,TGFBR3,TRH,UBE3A,AMOT,SLC17A7" Drug 5821_DN Tetrandrine [518-34-3]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADRA1D,APP,PDE8B,CFLAR,CA12,CAMK2G,KIAA1549L,CLU,WHRN,CSF1,SIRPA,MED12,ERBB2,ERCC2,CDKL3,FHL1,TRMO,CELF1,TRAF3IP2,PRRC2B,ARHGAP19,ITPKB,MYO6,PDE1C,PLCD1,LRP12,PTPA,PTN,SH3TC2,ZDHHC14,BSDC1,RGS10,SEC61A2,PAQR6,SPTAN1,ZBTB43,LHPP,MAPK8IP3,ELOVL4,TTBK2,COBL,KAZN,WSCD1,TCF4,SATB2,NSD1,ATP13A2,ZNF384,LMF1,MAP3K12" Drug 1500_DN Tolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "NDRG3,OSBPL1A,ANK3,APC,ARRB1,MTMR9,CFLAR,BMP7,VAX2,SLC4A7,CHD1L,ABCG1,MICAL2,GIT2,FBXL5,SMG7,HIPK3,SORBS3,EZH1,TESK2,KAT8,PDLIM5,TXNL4A,SLC2A6,KIF5C,CNOT4,NPR2,PLXNB1,PMP22,MAPK8,GON4L,WDR25,CCDC25,FBXW7,FUZ,EPN2,KDM4B,WDTC1,SP2,ZNF423,SPTAN1,TROVE2,SYT1,MCF2L,TRIM2,PCDHA6,ZNF34,KCTD2,XRCC4,GDPD5" Drug 2866_UP Budesonide [51333-22-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADCY2,ADORA1,ADRA1B,MRTFA,CDC42BPA,CDK13,ATM,STX16,NRP2,CACNA1G,CA4,NEURL1,IPCEF1,CNTNAP2,ARHGEF4,CTIF,CDON,SHANK1,ATN1,DTNB,EGFR,ANKMY1,TUBB4A,DLC1,SORBS1,PRELID3A,SIGLEC8,GNAL,PCLO,GRIK5,MSR1,TMOD2,SERPINE2,PIK3CD,MTRF1L,PACSIN1,ZNF493,S100B,SALL1,STUM,ASAP3,SLC14A1,NMNAT2,ZBTB43,NPAS3,POGZ,ARC,TPM3,AMOT,KCNAB1" Drug 7521_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABHD6,ADORA1,AP2A2,ALCAM,BIN1,APAF1,APC,APLP1,PPFIA3,CFLAR,CA4,FOXN3,WHRN,CREM,NCOR2,ANKMY1,TESK2,FGFR1,BAIAP2,FOXF2,DPYSL4,GNG4,GPER1,GRB10,AFF1,NNAT,DUSP26,LRP12,CNNM2,WDR25,RGS12,WLS,ZNF821,BTBD7,KDM4B,ZCCHC24,KDM4C,UNC5B,TTBK2,PHLDB1,IQCE,PARD3,CHST5,METTL3,VAV2,MICAL1,KCNK12,ZNF24,GDPD5,ITM2C" Drug 5068_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "TRMT9B,BIN1,EPB41L5,BACH1,SYNJ1,FOXN3,DNAJB5,ARMC8,NRG2,CREB5,SDC3,ARHGEF4,MFAP3L,SMG7,KBTBD11,CHRDL1,EXOG,EDIL3,EFNA3,MBNL2,STX2,ZNF549,TDRKH,MUM1,IL6ST,MEF2C,NF1,PRKAB2,MAPK3,SYTL2,ELOVL2,ZSCAN2,CEP97,GAL3ST4,SUPT20H,ZFP30,SLC4A3,PPP4R3A,IQSEC2,CEP68,SYT11,ASTN2,KAZN,TK2,RIMBP2,METTL3,OSBP2,LAT2,WNK1,EVI5" Drug 2443_UP Cisapride [81098-60-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABAT,C3orf14,ADGRF5,APBB2,STX16,ADAM23,HAP1,CHM,DNAJB5,SLC4A7,CTNND1,CTNND2,EDRF1,TBC1D5,DAPK3,SMG7,ERBB2,PTK2B,DLC1,FER,OLFM1,PDLIM5,CAMKK2,ZMYND11,GNG4,GPM6B,GRIK5,HTR2A,NELL2,TREM2,PDE4D,CCSER2,PLP1,TNPO2,MAPK7,ZFHX4,ROM1,TCP11L1,ZNF821,SLC1A3,SLCO1A2,SLN,RIMS1,DNMBP,WWC1,PSD3,ATP13A2,ZMYND8,NSD2,JPH3" Drug 5695_DN S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "AP2A2,AP1B1,ARRB2,FUBP1,BTRC,CA4,CA12,B4GALT6,SDC3,DCAF8,GIT2,RUSC2,SORBS3,IRAK4,EN2,ANKMY1,FGFR1,IQCG,ANKFY1,GPR153,GALC,MALT1,GLYR1,ITPKB,KCNF1,KHK,LMO2,KITLG,MMP16,MPP2,LYRM9,NF1,CNOT4,SLC25A23,SNRK,TMEM104,ELOVL2,PEX5,RALGDS,GTDC1,RPS6KA2,FERMT1,SLC1A7,WWC1,TCF7,RPGRIP1L,TMOD1,ZBTB14,SYNC,PRDM2" Drug 668_UP monastrol; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "BIN1,PPFIA1,SEMA4G,ASCL1,EIF4G3,STX16,ATP2B2,CFLAR,BMP7,CACNA1I,HAP1,CCNT1,CHRNB2,CNOT8,TMEM184B,CNTN1,CRYM,DMD,ABI2,FCGRT,USP19,RUNDC3A,CACFD1,MAN1B1,ICA1,KCNMA1,GPSM2,FA2H,MED1,PPP2R2B,MAPK7,RGS3,ARHGEF10L,GSTCD,MAPK12,ZNF821,SGK1,PPP1R9A,ASAP3,SLC12A4,SLN,PHLDB1,ARHGEF9,EXOC7,TCF4,CHST5,ZNF189,WNK1,SLC17A7,NUP214" Drug 7028_UP Isoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SEMA6A,MRTFA,APBB2,ARRB1,CFLAR,MTMR3,GYG2,CA4,CBFA2T2,PDE4DIP,ARHGEF4,RUSC2,DMPK,ATN1,RCAN1,EDNRA,SIDT2,MBNL2,ENO2,LRRC23,F5,FHL1,AGAP2,IQCG,DPYSL4,FAM49B,GAD1,GLYR1,GRB10,SLC2A6,ATXN2L,ELOVL5,LSS,KITLG,NASP,PTCH1,SELL,FBXO11,SMTN,SLC20A2,SNCA,VAMP1,PLCB1,KIAA0930,ZNF34,SLC44A1,KCNK12,SPHK2,MAP3K12,ST7" Drug 389_UP wortmannin; Up 200; 0.01uM; HL60; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ANK1,APP,ARNTL,BACH1,WASF1,CA12,DLGAP1,PCYT1B,NCOR2,INTS1,GIT2,MAMLD1,EEF1A2,FAM13A,ELAVL4,ZNF391,BAIAP2,B4GALNT1,CACFD1,NR3C1,GRM7,GRM8,BTN2A1,GUCY1A1,PADI2,MX1,NHLH1,NNAT,SLC11A2,NUMA1,OCRL,C11orf49,PACSIN1,PRKAR1B,RAP1GDS1,DPF2,KCNIP2,SATB1,FUZ,EPN2,SMARCD3,ARHGEF9,MCF2L,AHCYL2,KCTD2,PARD3,VIPR2,NAV3,KCNAB1,MPPE1" Drug 5325_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABR,RIPK1,CFLAR,SCARB1,PLEKHB1,ENTPD4,AKAP12,GIT2,RCAN1,EFNA3,CELSR3,SUGP2,SORBS3,MRNIP,EPB41L2,COQ7,ANKMY1,CELF1,AHDC1,NR3C1,KIF2A,MAP4,MBD1,OPA1,PDPK1,PRODH,PRPH,PTK2,QDPR,RIC8B,SGK1,ITSN1,ABLIM3,SIRT2,SLC22A4,KDM4B,SPTAN1,VAMP1,ARHGEF9,SEMA4A,TBL1X,BHLHB9,KAT6B,CABIN1,CDK20,ZMYND8,SSBP2,CADM1,VGF,AAAS" Drug 2244_UP Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,ADRA1B,AMH,AMPH,ARHGDIG,CADM3,CACNG1,NEURL1,ADGRG1,TAOK2,SULT4A1,AKAP6,ATRNL1,DOCK4,SPOCK2,DMPK,DYNC1I1,HEYL,EFNB3,EFS,SPEG,ETV1,REEP2,OGA,GABRA2,NEU3,RND1,MSL3,GRK4,SMAD1,OPRL1,PACSIN1,PRKCB,MAPK7,SAMD9,RPS6KA2,STUM,ST6GAL1,SLC4A3,SLC1A7,SLC9A5,SLC11A1,SP4,SPTB,ATP10B,TRPC3,CLIP2,GDPD5,MVB12B,AP3B2" Drug 2215_DN Disulfiram [97-77-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "BIN1,PLA2G4C,ASPH,BCL7A,CCNT1,CDH10,CLGN,CRLF1,FOXN3,NECTIN3,SDC3,MFAP3L,SMG7,SLC12A6,EFNB3,EGFR,EIF4G2,SORBS3,EPB41L1,F3,FHL1,GCNT2,GNG4,TDRKH,STON1,GPER1,GPR37,GRIK5,ATXN2L,HNMT,MAP4,NRGN,CDK18,GSTCD,MAP6D1,WLS,EPN2,SPART,ST5,PHLDB1,ROBO3,RPGRIP1L,ARHGEF12,CRTC1,CHST8,THRA,FAM155A,SYNC,KCNAB1,NUP214" Drug 2819_DN beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ARID1A,NDRG2,NME5,CDC42BPA,MARK4,ADAM15,SYNJ1,CACNA1D,CDH10,CNTN1,AKAP5,CSF1,CTH,EDRF1,RIMS3,DNM1,DSCAM,SIDT2,MBNL2,FOXG1,SRCAP,POLL,STON1,GPR22,RASSF8,HNMT,IL6ST,INPP1,KPNA5,MOBP,MX1,NF1,NPTX1,NTRK2,PIK3CD,STRN3,PPP2R2B,ZSCAN32,SLC1A7,STX1A,KAZN,IQCE,SYNE1,TNS2,PCDHA6,AHCYL2,TGFBR3,SLC44A1,TK2,EPM2A" Drug 2012_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "APOC1,ASPH,BCL7A,ST3GAL5,PTBP2,CLDN10,ARHGAP33,NIPBL,CRY2,ARHGEF10,SOCS5,CX3CR1,ARHGAP32,CELSR3,IRAK4,VPS26C,ANKMY1,C1orf61,FYB1,CACFD1,ITGA7,KHK,KIF5A,MAP4,NF1,PAK3,CCSER2,PLEC,RET,GSTCD,TCP11L1,HUNK,SCP2,ITSN1,AMBRA1,RAB3GAP1,KBTBD4,ELMO2,MAPKBP1,SPART,SRPK2,FCHO1,SYT11,CRTC1,PARD3,NPL,CHST5,ZNF23,PRDM2,ZNF248" Drug 6001_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "AP2A2,C1QTNF1,KCNAB2,CACNB2,HAP1,NEURL1,CHM,CLCN4,CNTN1,RIMS2,JAKMIP2,GSDME,EFNB3,EPB41L1,SEMA4D,DKK3,ALDH1L1,GPM6B,PTPRT,GUCY1A2,GUCY1A1,KLF12,HLF,IRF8,KCNN1,LIG4,MDM4,MYT1,NCAM1,PFKFB2,ELOVL2,ZDHHC14,WLS,SH3BP2,SH3GL3,SYBU,PPP4R3A,PDZD2,TNIK,TSNAXIP1,PHLDB1,ACSBG1,SZT2,DOCK9,AP4E1,TGFBR3,CHST5,ZNF74,ITM2C,SSPN" Drug 7184_DN Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABHD6,AK2,C5,HOMER3,SLC4A7,CDC42BPB,CREM,DCAF8,NR1D2,SEZ6L2,MRNIP,FYN,B4GALNT1,SEPT9,CLASRP,MBD1,MIA2,MITF,PC,MED1,PRKAR1B,VPS13C,RAB5B,RAD51D,BSDC1,MSANTD2,SEC61A2,RIC8B,C12orf49,FBXW7,PAQR6,SEC14L1,CCDC92,MAPKBP1,ZHX3,ZBTB43,NCDN,ARHGEF9,PJA1,IQCE,TRIM2,TNS2,TSC2,VAV1,ZNF24,TFIP11,WNK1,MVB12B,MARCH8,ZNF248" Drug 2566_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "MRTFA,CDC14B,CACNA1I,CACNB2,CDH10,HOMER3,ARMC8,FAM149A,VCAN,CDON,EDNRB,FCF1,SORBS3,ELN,RASGRP2,GAD2,ZMYND11,ERAP1,SEPT9,SRCAP,MAN1B1,ATXN2L,KLF12,KHK,MDM4,MEF2C,SCAMP5,MID1,AFF1,AFDN,MYO6,NTRK2,NLE1,MAPK7,LRRC49,SYTL2,PTN,MRAS,LIMS2,SLC11A1,EMC1,TBL1X,THRA,TPM3,UBTF,LMF1,XRCC4,KCNAB1,UBE3B,KAT6A" Drug 142_UP tolbutamide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ALCAM,PPFIA1,ALDH4A1,BCL7A,NRP2,BMP7,SLC25A14,HIP1R,CBR1,SYNGR3,AP4M1,ZMYM4,ZBTB24,LYPD1,DMPK,MED12,DTNA,SIDT2,SH3GLB1,MBNL2,SORBS3,TAOK3,AFF2,SARAF,ATXN2L,JAK2,KIF5C,LIMS1,PAXBP1,MBD1,PTOV1,PC,PLEC,RETREG2,PRKAR1B,SUSD4,ZDHHC4,RGS12,NEK11,GALNT10,MYCBP2,FCHO1,SEPT8,TBL1X,ATMIN,TP53BP1,ZMYND8,UBE3A,ZNF142,GDPD5" Drug 4007_DN "Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASIC1,ARID1A,ADRA1D,BIN1,APC,CDC14B,PDE8B,ALDH4A1,ALDH7A1,C5,RAB26,HOMER3,WHRN,NRG2,AATK,CSNK1E,CDON,ATN1,AASS,LRRC23,MTSS1L,EZH1,CINP,DISC1,SEPT9,LPAR4,GRM8,GUCY1A2,GIT1,ZNF862,ODF2,PEX5,RAB3IL1,KHDRBS2,RGS10,RPS6KA2,FRMPD1,ASAP3,SLC1A7,SLC6A9,TSNAXIP1,SPTAN1,MAPK8IP3,KIAA0930,RIMBP2,OSBP2,LMF1,KCNAB1,KAT6A,TIGD6" Drug 5756_DN Thiethylperazine malate [52239-63-1]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "C1QTNF3,KCNAB2,ALDH7A1,SCAPER,CA8,CDC42,LARGE1,CLCN4,CSF1,DZIP3,EDRF1,LYPD1,SMG7,RBM12,EIF4G2,FGF1,GLYR1,KCNMB4,PCLO,DHX35,IL12A,KCNH2,MAPT,MDFI,MIA2,ZNF862,NDP,MBOAT7,PPARA,MAPK7,FAM120C,RAB3A,RGS7,GSTCD,ROM1,SH3BGR,LIMS2,BEX1,THSD1,COBL,KAZN,SZT2,GPR161,BHLHB9,TNS1,XRCC4,WNK1,HPS4,EPM2A,ACTR3B" Drug 5421_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "RALGAPA1,ACTN2,SLC12A5,LTBP4,APC,APOC1,DNAH17,MARK4,SYNJ1,SCARB1,CHM,LHX2,STOML1,FADS2,SH2B1,RIMS2,TBC1D5,SMG7,CNNM1,SORBS3,EIF5,ING4,ZNF589,OGA,SEPT9,AHDC1,RUNDC3A,SLC2A6,DHX35,KCNH2,MATN3,MIA2,ADAM22,SERPINI1,NLE1,PLXNB1,FSD1,PRKAR1B,PEX5,ATG16L1,RPS6KA2,SLC1A7,SMTN,ZSWIM8,UNC5B,SEMA4A,ARHGEF12,HEY2,TNS1,EVI5" Drug 6836_DN Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SLC12A5,ALCAM,CDC42BPA,CAPRIN2,BTRC,FAM189A2,AKAP7,CREM,CRY2,SDC3,CTNND2,PPP6R2,EDRF1,ARHGAP32,DTNA,TNK2,RRAGB,EZH1,BAIAP2,GLS,TDRKH,GPR37,ITPKB,MAPT,MEIS1,KITLG,MMP16,LYRM9,NF1,CCSER2,TMEM231,RAB3IL1,ZDHHC14,MSANTD2,RGS12,RIC8B,FOXRED2,SEC14L1,SLC9A5,TTC17,EMC1,TSPYL2,FCHO1,PCDHA6,TK2,PARD3,TRIO,MICAL1,MPPE1,EPM2A" Drug 1470_UP Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,BIN1,CDC42BPA,APBB2,APLP1,ATP2B2,ATP6V0A1,GYG2,CAMK2B,TAOK2,RAB33A,ZFYVE9,QKI,HOMER3,DAPK3,DMPK,DSCAM,EDNRA,KIAA1109,FGFR1,SEMA4D,GATM,GLYR1,POLL,GNAL,GPD2,GSTM5,HNMT,INPP5B,MYO7A,NNAT,PCBP3,RELN,CNTLN,PTCH1,PTHLH,PTH1R,RAD52,SALL1,KIF13A,RBM34,EMC1,ARC,IQCE,SZT2,CHST8,WIPF1,HPS4,MVB12B,DPF3" Drug 1915_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HG-U133A" Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASIC1,ACLY,ADD2,EP400,PPFIA1,KCNAB2,RASL11B,RGS11,P2RX6,NIPBL,AKAP7,SLC4A7,CRY2,ARHGAP32,ARHGAP24,DCAF8,SPOCK2,GIT2,B3GAT3,RUSC2,DTNA,EDN1,SRPK3,FER,C1orf61,SMC2,PDLIM5,HTATSF1,PRRC2B,PADI2,ARHGAP19,IL12A,KIF2A,IPO5,MYL3,NPPA,OMG,PIK3R1,PMS2,MAPK10,BSDC1,TCP11L1,ZNF331,SMARCD3,LHPP,TTBK2,NSD1,TSC2,MPPE1,AAAS" Drug 6632_DN SR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "RALGAPA1,BIN1,CDC42BPA,APBB2,ST3GAL5,MYRF,SOCS6,CLCN4,CREM,SH2B1,ABCG1,ARHGEF4,TOX,ARMCX2,MFAP3L,FBXL5,SMG7,TNK2,MRNIP,COQ7,C1orf61,DENND2A,GAD1,GLYR1,POLL,TDRKH,HLF,MDFI,ADAM22,PDE1C,PPARA,WDR25,RAB3A,SH3TC2,ZNF821,BCAN,MYH15,IQSEC2,ZBTB43,CAMTA2,MAPK8IP3,SUPT5H,WWC1,SMG6,TCF4,SZT2,TNS1,RPRM,LMF1,MAP3K12" Drug 1318_DN Metrizamide [31112-62-6]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "CDC42BPA,APAF1,ARNTL,NCOA1,CAPN3,FOXN3,SOCS6,TPP1,FADS2,TMEM184B,COL9A2,SLC4A7,HINFP,SIPA1L1,SLITRK5,CTIF,KIAA0753,DPH1,EEF1A2,IGSF6,SEMA4D,TJAP1,MAP4,NUCB1,SETD4,RETREG2,PTPA,SAMD9,SIDT1,ATG16L1,EXD2,CCDC25,TCP11L1,ATXN1,FAM214B,SLC6A8,KDM4B,WDTC1,ZCCHC24,ZBTB43,CAMTA2,ARHGEF9,TCF4,NSD1,ZNF34,TNNT1,RBFOX2,ATP6V0E2,LAMP5,HPS4" Drug 6668_DN Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "OGT,CDK10,ZBTB10,ARHGAP33,KIAA1549L,ARMC8,WHRN,AATK,VCAN,PDE4DIP,ARHGEF4,SUGP2,SORBS3,TENM1,COQ7,ERCC2,ANKMY1,EFEMP1,FGFR1,IQCG,SEMA4D,DENND2A,ERAP1,C1QL1,GNAS,STON1,HLF,SYNPO,TJAP1,IL6ST,VWA5A,MAPT,NF1,CNOT4,PC,MAPK7,REV3L,RPS6KA2,ATXN7,ASAP3,TMCC1,IQSEC2,TAB2,SYT1,SYNE1,DOCK9,GPR161,CABIN1,TNS1,SENP7" Drug 4348_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "NDRG2,ADD2,AP2A2,APOC1,APP,MARK4,ASPH,VCAN,DOCK4,TOX,EDN1,SGK2,ELN,EN2,F5,FGF14,ATP8A2,GFER,GNAL,GRB10,CACFD1,GRM3,HLF,ICA1,MAN2A2,BCO1,OGG1,KCNK10,PALM,PLTP,CNTLN,PTHLH,PTPRH,RAD52,ZNF493,ST6GAL1,SYBU,SLC11A1,RIMS1,ZC3H13,COLGALT2,RGL1,TBCEL,SMG6,ZEB1,TNS1,CHST5,UGT8,DNALI1,JPH3" Drug 4636_UP Chlormezanone [80-77-3]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASPHD1,ADCY6,ADGRF5,CDK10,SLC4A4,N4BP2L1,KSR1,BSN,DLGAP2,STOML1,RAB26,NRG2,VCAN,PPP1R16B,SIDT2,EFNA3,CALCRL,FYB1,GAB1,GNAL,LILRA2,PTGDR2,IL6ST,LIFR,CLDN11,P2RY1,PDE4B,PDE4D,TNPO2,PPARA,PTH1R,ST8SIA1,PEX26,SLC20A2,TNIK,ZNF423,BEX1,ARHGAP26,ATP10B,NXT2,MAPK8IP3,PHLDB1,ARC,ASTN2,CRTC1,ZKSCAN5,VAV2,VLDLR,SPHK2,SLC17A7" Drug 418_DN haloperidol; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ACADM,CDC42BPA,DGKD,APP,AQP6,PDXK,ARNTL,ASCL1,OSGIN2,HIP1R,NEURL1,TBRG4,PLEKHB1,TJP2,RIMS2,KIAA0513,ARNT2,E2F5,ABI2,ETV1,TAOK3,KAT8,FAM49B,CAMKK2,ZNF44,ZNF276,LAMP2,MBD1,MTR,NFYA,RALGDS,SUSD4,SHMT2,CDK5RAP2,USP33,NMNAT2,CDK19,COBL,TRIM2,TRIO,ZMYND8,SSBP2,VIPR2,XRCC4,SPHK2,ZNF189,ZNF195,GDPD5,MPPE1,AAAS" Drug 6466_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "CDC42BPA,ARHGDIG,ARRB1,ALDH4A1,SLC4A4,USP2,DGKI,CHRNB2,CNN3,SDC3,CTH,CEND1,CORO2B,KAT8,KIAA1109,OLFM1,FGFR1,C1orf61,AGAP2,GAD2,HBS1L,TMEM8B,KLF12,HLF,ICA1,KCNK1,KCNMA1,KCNN1,KCNN3,PACRG,MDM4,MSR1,CDK18,PDE3B,PLCD1,FA2H,LRRN3,MAPK7,PTHLH,PDZD2,WDTC1,ZCCHC24,SOX10,PEG10,AJAP1,KAZN,EXOC7,TRIM2,WIPF1,SLC30A3" Drug 6907_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "APOC1,CDC14B,RGS20,MTMR2,CHN2,DNAJB5,AATK,ARHGAP24,MFAP3L,MAGI2,RHOBTB1,G3BP2,SEC24B,KIAA1109,FHL1,WASF3,GLRB,KCNMB4,GNG3,LIG4,ARHGAP12,MEIS1,NF1,PALM,SERPINI1,NLE1,GON4L,CNTLN,PTPRN2,ATG16L1,SUGCT,HSPA4L,SH3BP2,AMBRA1,ST6GAL1,SNCA,EXOC7,KIAA1107,TNS2,HEY1,TPM2,ZMYND8,SSBP2,HIRA,LMF1,TFIP11,PCBP4,PLSCR4,SMIM8,GAN" Drug 362_UP rapamycin; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "NME5,KIAA1324,AQP6,ASCL1,SLC4A4,CADM3,SCAPER,CACNA1I,CAMK2B,SULT4A1,AKAP7,CALY,RIMS2,ECE2,BRINP1,GIT2,TMCC2,EFS,IQCG,ATP2C1,NEU3,RUNDC3A,GUCY1A1,IL6ST,KCND3,KCNJ3,KIF5A,MAOB,NTRK3,OMG,OXTR,GPR173,SH3GL3,FUZ,ZKSCAN3,SCN3B,TNIK,ZCCHC24,ZSWIM8,HECW1,ZC3H13,STX1A,VAMP1,DNMBP,CAMSAP2,TCF4,PHF24,CRTC1,SLC13A3,GDPD5" Drug 4390_DN Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SLC12A5,AMT,EP400,KCNAB2,APC,APP,NUMB,CA4,CAMK2B,ARHGEF1,ARHGEF2,MAGI1,CLGN,ADGRG1,SOCS6,DNAJB5,QKI,AKAP7,SLC4A7,CREM,ABCG1,EML1,ZMYND11,NCKAP1,POLL,IL6ST,MAPT,TM6SF1,KITLG,CNOT4,RC3H2,MINDY2,GRAMD1C,ZSCAN32,RAB5B,SLC15A2,LIMCH1,ZHX3,ATP11A,TRIM2,SZT2,CRTC1,PCDHA6,SLC44A1,CDK20,HIRA,VLDLR,EMSY,ST7,SSPN" Drug 4571_UP Levodopa [59-92-7]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "DPF1,TRMT9B,ASPH,ZSCAN18,MTMR3,CBS,CDH10,CRLF1,ABCG2,CREM,CNTNAP2,SDC3,CTNND2,ST18,TOX,MAML1,MFAP3L,TENM1,MTSS1L,ANKMY1,FGFR3,GABRA2,SEPT9,GFRA1,MSL3,CACFD1,KCND3,KPNA5,PALM,PDE4D,PIK3R1,PLCD1,PLP1,MINDY2,PTCH1,PTN,FBXW7,CPEB3,SLC1A7,SLC11A1,DOK5,SPTB,ZBTB43,PHLDB1,SMG6,TIAM1,TMOD1,ZNF24,STMN4,SEMA3B" Drug 6444_DN (S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "AK2,AMPD3,APOC1,CDK10,PLA2G4C,DNAH17,MARK4,CFLAR,LDLRAD4,MAP7,ZFYVE9,BAG4,ENTPD4,TM9SF4,LYPD1,EGR3,IRAK4,FGFR1,FAM49B,PRELID3A,INPP5K,ZNF276,HNMT,ITPKB,IPO5,MAPT,PDCD2,PIK3CD,RIPOR1,CEP97,RAD52,RGS3,ARHGEF10L,DCUN1D2,ROBO1,NEK11,WLS,SAFB,SYBU,SLC1A7,SMTN,FBXW11,TCF7L2,AHCYL2,SLC44A1,ZKSCAN5,UBTF,REEP1,HPS4,ACTR3B" Drug 5280_UP Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,BIN1,GAS7,APOC1,CAMK2G,ADGRG1,CHI3L2,CABP1,IFFO1,CRMP1,SDC3,RIMS2,DCAF4,CYBB,RUSC2,DMPK,DTNA,PHF20L1,OLFM1,FOXG1,PDLIM5,OGA,ALDH1L1,GCNT2,C1QL1,RUNDC3A,GRIK5,GRM2,IRAK3,HLF,ICA1,ITIH2,KCND3,AFF1,AFDN,MOBP,NF1,DCHS2,KLHL11,RPS20,KANSL3,SNAP25,EMC1,POPDC3,DMXL2,DOCK9,HEY2,R3HDM1,CHST5,KCNK12" Drug 2062_UP Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADGRF5,PDXK,BTRC,NRXN3,CLCN3,NMT2,ARMC8,ABI3BP,CREM,CNTNAP2,EDRF1,CTIF,C2CD2L,RABGAP1L,FAM13A,MBNL2,MTSS1L,ANKMY1,FGF1,SESN1,MSL3,GNAL,CNTRL,IFI16,GIT1,FSD1,APTX,GON4L,PTN,TMEM231,GAL3ST4,KCTD17,ATXN1,SUPT20H,SCG5,FRMPD1,FAM214B,IFT122,LIMCH1,TROVE2,RGL1,VAMP1,SMG6,KIAA0930,ARHGEF12,WIPF1,XRCC4,ZNF45,EMSY,PRDM2" Drug 6569_DN 5155877; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "C1QTNF3,APBB2,SEMA4G,PDXK,MTMR9,RIPK1,CFAP410,CCNT1,LHX2,NMT2,ABI3BP,NRG2,SOCS5,CNTNAP2,SLITRK5,SPOCK2,DTNA,APH1A,ETV1,KIAA1109,B4GALNT1,HTATSF1,MBD1,MDFI,MN1,NDP,NFYA,NPR2,OGG1,PAK3,PDE1C,FSD1,RGS7,SH3BP2,CNKSR2,LIMS2,KDM4D,SIRT2,SPTAN1,PBLD,SYT11,PSD3,TK2,HIRA,CADM1,WIPF1,HPS4,NAV3,KCNAB1,KAT6A" Drug 5876_DN Convolamine hydrochloride [500-56-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABHD6,AMT,KCNAB2,CDC14B,ALDH7A1,CFLAR,CDK5R1,CCNT1,LARGE1,LHX2,QKI,TM9SF4,DBT,DCTN1,SGSM2,PLXNC1,EPB41L2,VPS26C,SEMA4D,TPK1,TRAF3IP2,GAD1,SRCAP,COPS8,GPM6B,BTN2A1,DHX35,MEIS1,MMP16,MPP2,TAGLN3,SLC11A2,CCSER2,POLG,BSDC1,GTDC1,TTLL7,MAP6D1,TMEM156,PEX26,INTS9,MAPK8IP3,ATMIN,TCF4,ARHGEF12,BHLHB9,TRPM2,EMSY,HPS4,NUP214" Drug 1989_UP Antipyrine [60-80-0]; Up 200; 21.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "CDC42BPA,APBB2,CDC14B,SEMA4G,BCL7A,CFAP410,KRIT1,P2RX6,ARHGAP33,SRSF11,SLC4A7,CTH,KIAA0586,DAPK1,SPOCK2,ABI2,PLXNC1,IGSF6,EFS,CD320,ACSL4,SPIN1,GNG3,GPR12,GRIA4,SLC2A6,MYT1,SETD4,CAMKV,ZNF426,PACSIN1,VPS13C,MSANTD2,MRPS18A,MYH14,ATXN1,NUBPL,KBTBD4,KDM4B,ATP10B,POGZ,LARP4,GSE1,MGRN1,EHBP1,ZEB1,KCTD2,TNS1,HIRA,VIPR2" Drug 6841_UP Furosemide [54-31-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,ADORA2A,MRTFA,APLP1,ATP2A2,CFAP410,CACNG1,CALB1,CLGN,CHN2,EPS15L1,NECTIN3,RIMS3,RUSC2,ATN1,TENM1,SPEG,FOXG1,AFF2,SORBS1,TPK1,GNAO1,SPACA9,GRM1,GRM8,HNMT,VWA5A,MITF,NCF2,TREM2,PENK,LRRN3,FAM120C,RAD52,TTLL7,RYR1,RASA3,PPP1R9A,ASAP3,ZCCHC24,KIF21B,HECW1,MAPK8IP3,ZFPM2,TRIO,UCHL1,PDIA2,FLRT2,LAT2,GJC2" Drug 2715_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADRA1D,KIDINS220,AMH,APBB2,PPP4R4,LDLRAD4,EPS15L1,QKI,NRG2,CSF1,SIPA1L1,PPP1R16B,C3orf18,MTSS1L,PIPOX,F5,KIAA1109,FGFR1,FHL1,FYB1,GATM,ZNF276,MSL3,GPM6B,TJAP1,IL6ST,MEF2C,AFDN,NNAT,NUMA1,PCDH9,ENPP2,PTN,ZSCAN32,TMEM206,SEC14L1,PREX2,PEX26,SLC11A1,SPTB,LHPP,ADGRL3,SYNE1,THBS4,TK2,TPM3,REEP1,SH3GLB2,SYNC,TIGD6" Drug 267_DN genistein; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "KDM5D,BIN1,AMT,ANK2,GAS7,ARSF,ASCL1,CADM3,ATP6V0A1,NRP2,CALB1,CAMK2A,ADGRG1,SOCS6,CHRNB2,JAM2,RAB28,SULT4A1,CNTFR,PCYT1B,CRMP1,CHD5,DRP2,ATN1,ECM2,EFNB3,GAB1,SEPT9,SRCAP,GRIN1,BTN2A1,NCKAP1L,ATXN2L,L1CAM,LIG4,NPPA,NTRK3,PLCD1,PLXNB1,PTN,MARCH1,RAD52,EMID1,SYNDIG1,DOP1A,UNC5B,ZFR2,COBL,SEZ6L,VIPR2" Drug 6416_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,ADRA1D,ADGRF5,TRMT9B,APBB2,GAS7,BCAS1,PLA2G4C,CADM3,LDB2,SOCS6,SULT4A1,NRG2,AATK,RGS6,CNTNAP2,ATN1,DTNB,ST8SIA3,SNX29,ANKMY1,DLC1,PDLIM5,FYB1,C1QL1,LPAR4,C2orf72,KCND3,KHK,MAP2,MARK1,PCBP3,NTRK2,CAMKV,SMOX,PKN2,FAT4,SCG5,PKNOX2,RIMS1,SP4,PEG10,MAPK8IP3,ZEB1,ARHGEF12,TTPA,TUBB1,UGT8,NLRP3,SENP7" Drug 6420_DN Orlistat; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "BRAP,ADORA2A,LTBP4,TRMT9B,DNAH17,MARK4,GYG2,TPP1,CREB5,EDRF1,SPOCK2,PLEKHA1,TNK2,COQ7,STX2,FGFR1,PDLIM5,AHDC1,POLL,PRRC2B,GRK4,RASSF8,ELOVL5,LIFR,MAP4,SCAMP5,ZNF862,NF1,SLC11A2,PAK3,STRN3,RAB3A,ZDHHC14,KIRREL1,STUM,MRAS,SLC12A4,CDK5RAP2,KDM4B,DOP1A,EMC1,SPTB,NPAS3,CEP68,PCDHA5,CABIN1,TNS1,ZNF32,WNK1,DPF3" Drug 6489_DN Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "AMH,APC,EPB41L5,CFLAR,C5,CA12,MAGI1,CTNND1,DBN1,DBT,TRAPPC9,SIDT2,EGFR,BAIAP2,SEMA4D,PDLIM5,INPP5K,SRCAP,AHDC1,GNG4,SPACA9,GRM1,KCNH2,MAP4,GIT1,ZNF862,NF1,NUCB1,POLG,CNNM2,RIPOR1,EMID1,SAFB,ZNF821,SH3BP2,ABLIM3,SMTN,SLC22A4,ZHX3,UNC5B,TACC1,EXOC7,CDK20,SSBP2,VLDLR,KLC2,KCNK12,XRCC4,MAP3K12,ST7" Drug 5853_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "RALGAPA1,ACTN2,NME5,DDO,CDC14B,PPP4R4,ADAM23,SYNJ2,RAB29,MYRF,CDC42,CHM,SULT4A1,AKAP7,SLC4A8,RNF14,TENM4,NOS1AP,DTNA,LPAR6,TENM1,DLC1,AGAP2,DLL3,TBR1,GPR37,IGF1,ITIH2,KIT,MOBP,PLCD1,POLG,PPP5C,MAPK10,SAMD9,BCAS3,PTN,FAM184A,RGS12,ZNF334,SAMSN1,PLCB1,ARC,TRIM2,SLC44A1,TIAM1,ZMYND8,WIPF1,ZNF711,GAN" Drug 2461_UP Iohexol [66108-95-0]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "APC,CDK10,GYG2,BAIAP3,CDH2,CREM,SIPA1L1,PDE4DIP,EDRF1,DNAJC6,DLG4,ST8SIA3,SORBS3,ANKMY1,NCKAP1,SIGLEC8,SRCAP,AHDC1,GNG4,GRM1,ATXN2L,HNMT,KCNN1,MID1,MMP16,MYO6,NEUROD1,NRCAM,EPN1,WDR25,RGS12,ZFHX4,PNMA8A,SH3BP2,RPH3A,SMTN,SLC6A9,SLC11A1,LIMCH1,SOX15,IZUMO4,SEPT8,RPGRIP1L,THRA,CHST5,AMACR,LMF1,SLC13A3,KAT6A,NUP214" Drug 5346_DN Calciferol [50-14-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ALCAM,APC,SLC4A4,CACNA1D,RAB28,COL4A5,DCAF8,SMG7,PARD6A,DTNA,TOM1,FECH,FGFR1,FHL1,DISC1,KCNMB4,CNTRL,GRM1,SLC2A6,IL6ST,JAK2,KIF2A,MAP4,NUMA1,RAB3IL1,GTDC1,PAQR6,MAPK12,AMBRA1,ZNF365,MAPKBP1,WDTC1,FNBP1,EMC1,ITPRID2,ARHGEF9,ANKRD12,EXOC7,WDR7,TMOD1,KAT6B,TRPC1,ZMYND8,VAV1,VGF,VIPR2,MAP3K12,HPS4,PCBP4,MVB12B" Drug 5497_DN Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABR,ACTN2,AP2A2,CDC42BPA,SCAPER,MAGI1,RAB28,DCAF8,KIAA0753,G3BP2,ATN1,RCAN1,EDNRA,EPB41L2,FHL1,GAD1,INPP5K,CRCP,POLL,MAP4,SCAMP5,LYRM9,NFYA,ODF2,OGG1,SLC25A23,FSD1,TMEM104,PEX5,NKAIN1,RGS12,FOXRED2,SH3BGR,BTBD7,TMCC1,RBM34,ERC1,POPDC3,TCF7,ZNF34,THRA,TK2,KCTD2,CABIN1,CDK20,ZMYND8,KLC2,HPS4,MPPE1,KAT6A" Drug 3618_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,SPARCL1,MARK4,BRINP2,HAP1,CAMK2B,CAMK2G,CHM,CRMP1,CSF1,MICAL2,SPOCK2,DRD1,EDN1,SGK2,RASGRP2,CACNG3,CAMKK2,CSPG5,GABRG2,FERMT2,GRM3,INPP5B,KHK,FXYD7,NPR2,NUMA1,PAX6,CDK18,PDE4B,RETREG1,C19orf57,ELOVL2,PTPRN2,MARCH1,CCDC40,C1orf54,GAL3ST4,KLHL11,SYNDIG1,FRMPD1,CNKSR2,ARHGEF40,SLC11A1,SORCS3,TNIK,ATP10B,SLC19A3,TNS1,AMOT" Drug 6693_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "APBB2,APOC1,APP,PDE8B,ASPH,MYRF,CDC42,ABCG2,RAB26,CSNK1E,VCAN,CNTNAP2,ARHGEF4,ARMCX2,RHOBTB1,TMCC2,STX2,EZH1,TUBB4A,TMEM8B,GPM6B,GPER1,GRK4,GRM1,GUCY1B1,KCNN1,TM6SF1,NF1,NOS1,OPCML,PDGFRA,PTHLH,KHDRBS2,GTDC1,RGS10,KIRREL1,FBXW7,MAPK12,ASAP3,AMBRA1,IQSEC2,DDN,SUPT5H,TMEM121,THRA,CABIN1,TNS1,LMF1,EVI5,KCNAB1" Drug 5703_DN Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "FZD9,TRMT9B,AMH,BIN1,CDC42BPA,PPP4R4,ALDH4A1,SLC4A4,ST3GAL5,CA4,CACNA1D,CBFA2T2,VAX2,SIPA1L1,CTH,NOS1AP,DAPK3,DRD1,ELAVL3,EML1,MTSS1L,STX2,IQCG,TBR1,USP19,PCLO,CNTRL,IL6ST,MAP2,AFF1,KCNK10,PDE4A,DCUN1D2,SBF1,SH3BP2,SOX2,ZHX3,KDM4C,ZNF423,TSPYL2,MAPK8IP3,ATP11A,EXOC7,TBCEL,ZEB1,TGFBR3,AMACR,MICAL1,ZBTB14,EVI5" Drug 5949_DN AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADRA1B,KIDINS220,PKP4,CDK10,PDXK,DDX3Y,ATP2A2,NRP2,PROM1,ST3GAL5,SCAPER,NFS1,ARHGEF1,CHGA,SOCS6,CREB5,NCOR2,CNTNAP2,RUSC2,RABGAP1L,ERCC2,NRN1,GCNT2,GPM6B,GPR17,GPER1,HSF2,SCIN,INPP5B,KCNN1,MAPT,MEF2C,AFF1,MMP17,P2RY13,CDK18,PPP5C,WDR25,PTAFR,PTN,RAD52,IFT122,KDM4B,POGZ,TNS2,FRYL,TIMP4,VAV2,KCNAB1,AAAS" Drug 6209_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ANK3,APP,CDC14B,BMP7,ARHGEF7,C5,CCNT1,SCARB1,SYNGR3,DCAF8,ZNF337,SMG7,MRNIP,EPB41L1,FHL1,DISC1,MALT1,GPD2,ARHGAP19,ICA1,MEIS2,MITF,NUCB1,ODF2,PDE4A,PDPK1,PLEC,PMP22,POLG,PRKAR1B,RIPOR1,NKAIN1,RAB3IL1,SUSD4,MSANTD2,FOXRED2,SAFB,IL17RB,SEC14L1,SGK1,AMBRA1,FNDC3A,INTS9,KDM4B,TROVE2,POGZ,TJP1,LMF1,TFIP11,PCBP4" Drug 2807_DN Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASPHD1,AP2A2,ALAD,MTMR2,KYAT1,CDC27,ZFYVE9,NMT2,COL4A5,CRY2,CSNK1E,PDE4DIP,HIPK3,SIDT2,ZNF589,FECH,BAIAP2,IQCG,SEMA4D,CINP,SYT17,RAB30,PRRC2B,MIA2,KITLG,NEK1,NRGN,SLC25A23,LRP12,RALGDS,ZCWPW1,GTDC1,RNASEL,SGK1,ITSN1,CDK5RAP2,TMCC1,WDTC1,CLSTN2,MCF2L,EXOC7,MGRN1,PSD3,TRIO,ZMYND8,PLPPR2,ZNF23,HPS4,EPM2A,GAN" Drug 6315_UP Prazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "RALGAPA1,NME5,PLA2G6,PKP4,PPFIA3,SHROOM2,HAP1,NRXN3,CLCN4,HOMER3,GAL3ST1,CPS1,SLITRK5,APPL1,PHF14,ARMCX2,EFNA3,COQ7,RRAGB,FGFR1,FLT1,PNMA2,FYN,DENND2A,ZMYND11,GALC,TMEM8B,INPP5K,ZNF276,AP4S1,HNMT,JAK2,MX1,SNTG1,GRAMD1C,CNNM2,RAB3IL1,RAD52,GSTCD,TCP11L1,SUPT20H,ZFP30,TNIK,TAB2,KIAA1107,SZT2,ZBTB14,NT5M,KCNAB1,PHTF2" Drug 2337_UP Kawain [500-64-1]; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "APC,MARK4,NCOA1,CAMK2B,CAMK2G,GPR37L1,ABCG2,IFFO1,ZFYVE16,ZNF337,BRINP1,MFAP3L,RCAN1,TUBB4A,HPCAL4,FOXG1,ZMYND11,SIGLEC8,ZNF276,GLRB,PRUNE2,LILRA2,MEF2C,MYO7A,NELL2,NNAT,SLC11A2,NUCB1,NUMA1,CCSER2,ST8SIA5,PLTP,PMP22,MAPK7,ZSCAN32,RASGRF1,GAL3ST4,ASIC4,FAM102A,FERMT1,PKNOX2,SLC6A9,KDM4B,IZUMO4,KIF1B,SYT5,HPS4,PCBP4,ST7,UBE3B" Drug 6249_DN Thiorphan [76721-89-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "KIDINS220,AK2,CDC42BPA,ATM,CAST,FOXN3,PLAA,ARMC8,SLC4A7,CREM,NCOR1,LRIG1,FEZ1,ARHGAP32,GIT2,DNAJC6,SGSM2,RABGAP1L,EXOG,FEM1B,SUGP2,F3,F8,FGFR1,TACC2,FYN,GNG4,PADI2,JAK2,CCSER2,PLXNB1,RETREG2,MED1,ARHGEF10L,ROBO1,FOXRED2,SFPQ,TMCC1,ZSWIM8,SPTAN1,FAM168A,SMUG1,HIRA,SF1,REEP1,WNK1,WIPF2,MPPE1,MVB12B,ACTR3B" Drug 5737_DN Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASIC1,NME5,APLP1,PPFIA3,CDK10,STX16,ALDH7A1,CFAP410,ASIC3,B4GALT6,TAOK2,RAB28,SULT4A1,SLC4A7,CSF1,ARHGEF10,CNTNAP2,EDRF1,TOX,TBC1D5,CDON,PLEKHO1,ETV1,F3,FGF1,FGFR1,TRMO,CGREF1,OGA,INPP5K,MSL3,KLF12,INPP5B,KIF5C,NF1,SERPINI1,MAPK3,PTPRN2,RIPOR1,FAM184A,RGS4,COLGALT2,SYT11,ATP11A,FAM155A,UGT8,TFIP11,UPF3A,UBE3B,PHTF2" Drug 2174_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "RALGAPA1,NDRG3,GRAMD1B,AP2A2,MTUS1,AMT,APOC1,NCOA1,KIF1A,SYNJ2,CLGN,RCBTB2,SOCS6,RAB28,SLC4A7,SH2B1,PDE4DIP,CST3,SLITRK5,SPATA2,FRY,LPAR6,ING4,TNK2,EIF1,RASGRP2,CD320,ZNF589,KIAA1109,PRKAG2,WASF3,HNMT,SMAD1,GIT1,NINJ2,PTPA,MAPK8,GON4L,PTAFR,DOCK10,CEP68,KANK1,SYT11,ATP11A,CAMSAP2,PDLIM2,TK2,TLR4,TNS1,UPF3A" Drug 6490_DN Iodipamide [606-17-7]; Down 200; 3.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SRPX,BCAS1,CFLAR,MTMR2,SLC25A14,CDH8,CDH10,B4GALT6,CHD1L,AKAP12,SIPA1L1,FAM169A,DZIP3,GIT2,JAKMIP2,ABI1,KCTD3,MALT1,COPS8,GPR37,DIDO1,ELOVL5,VWA5A,MAP4,NFYA,SERPINE2,FSD1,CNNM2,TMEM104,NKAIN1,SUPT20H,HSPA4L,SGK1,FUZ,ELMO2,SLC20A2,ZC3H13,SPART,TCF7L2,TK2,BEX4,RBFOX2,FAM155A,CLDND1,XRCC4,ZFAND5,HPS4,MPPE1,FZD3,RNF170" Drug 2162_UP Gelsemine [509-15-9]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "TRMT9B,APAF1,APOC1,APP,PDE8B,BMP7,MAP7,SLC22A6,DTNA,HIPK3,HEYL,SIDT2,EIF1,VPS13B,FOXG1,PRELID3A,GPR153,GALC,INPP5K,ALDH1L1,SRCAP,ADAM28,GPR22,GRM1,HNMT,TJAP1,NCAM1,PDE1C,PDE4D,ST8SIA5,ZNF426,CEP41,WDR25,PTPN13,RIPOR1,TMEM206,NEK11,SHANK2,EFHD1,TMCC1,ZCCHC24,CDK19,TSPYL2,SEPT8,CEP68,FAM168A,TAC3,RPRM,PLSCR4,SENP7" Drug 1500_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ABHD6,ADGRF5,AMT,APAF1,BCAS1,BACH1,MPDZ,CFLAR,ST3GAL5,MTMR2,BAIAP3,CFAP410,TAOK2,DNAJB5,NECTIN3,SH2B1,PDE4DIP,GPRASP1,MFAP3L,EDNRA,SCARA3,ANKFY1,EFCAB2,GABRA2,GRIK5,HPSE2,KCNMA1,MBD1,KITLG,MSI1,NPPA,SETD4,LRRN3,PLPPR1,PTN,ROM1,EMID1,SYNDIG1,FRMPD1,PPP4R3A,PKNOX2,EMC1,SPART,ST5,MAPK8IP3,TAL1,TRIM2,PSD3,NT5M,KCNAB1" Drug 996_UP LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASPHD1,ADCY6,SRPX,MRTFA,PKP4,EPB41L5,PPFIA3,MADD,CDK13,CA12,KYAT1,SLC4A8,PDE4DIP,MFAP3L,LYPD1,KBTBD11,DMPK,HIPK3,F3,KAT8,ZNF589,DPYSL4,HBS1L,B4GALNT1,ERAP1,GLYR1,GPD2,NR3C1,ATXN2L,ELOVL5,KPNA5,MITF,NDUFA5,NEK1,NF1,SLC25A23,PPP2R2B,RALGDS,FAM184A,SH3BGR,SH3BP2,ANKRD6,SLC15A2,BTBD7,SLC22A4,DIP2A,FBXW11,RPGRIP1L,VGF,EPM2A" Drug 5789_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "PLA2G6,PDE8B,MARCH3,ASPH,ALDH4A1,ALDH7A1,SCARB1,KIAA1549L,STOML1,ARMC8,SLC4A8,CREB5,SLITRK5,PARD6A,AK5,TOM1,ERCC2,FYN,GAD1,PCDH17,TDRKH,GPR19,ICA1,MAPT,NF1,PBX1,KCTD15,MAPK7,PTPRE,PTPRH,RALGDS,BEND5,RGS7,ARHGEF10L,CSRNP3,SELL,ZFP30,SLC14A1,BTBD7,SS18,FAM168A,MCF2L,TMEM121,THRA,TIAM1,HIRA,VIPR2,WIPF1,PRDM2,EPM2A" Drug 4803_DN Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "BRAP,BCAS1,ARHGAP5,ATM,CFLAR,CDK5R1,SCAPER,GYG2,CFAP410,ARHGAP33,SLC4A7,SIPA1L1,HDAC4,SMG7,DTNA,F3,FAM49B,KHDRBS3,GPR153,ZNF44,SRCAP,MALT1,MSL3,IL6ST,JAK2,MIA2,SETD4,PDCD2,PDE3B,PLEC,PACSIN1,PPP2R2B,PTCH1,ZCWPW1,RPS6KA2,SBF1,PEX26,RBM34,CEP68,TTBK2,PDLIM2,KIAA0930,CABIN1,TPM1,CADM1,KCNK12,ZBTB14,SYNC,WIPF2,KAT6A" Drug 1229_UP clozapine; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "MRTFA,AMH,SEMA7A,ARHGDIG,MARK4,BMP7,RAB33A,KIAA1549L,RAB26,AKAP7,EDRF1,TMCC2,SGK2,PLEKHO1,ERCC2,TUBB4A,STON1,GPER1,ICA1,TJAP1,MDFI,MKLN1,ZNF862,NF1,NOS1,OGG1,POLG,WDR25,PTAFR,TMEM231,RGS4,FBXW7,SUPT20H,SLC4A3,RPH3A,EPN2,BTBD7,SLN,SPTB,ARHGEF9,ATP11A,IQCE,TBL1X,TRIO,OSBP2,ZNF23,ZNF74,WNK1,SEMA3B,PLSCR4" Drug 4568_UP Sparteine (-) [90-39-1]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASPHD1,ACTN2,APC,ASCL1,CCDC181,ATP2B2,CADM3,ADAM23,CACNA1I,CAMK2B,CD86,CHN2,TAOK2,CLCN4,CREM,CNTNAP2,CTNND2,EDRF1,RABGAP1L,EDNRB,ING4,ZNF391,ETV1,ST3GAL6,CAMSAP1,PDLIM5,GPR17,GRIA4,GSN,SOX21,HRH3,ICA1,LMO2,TM6SF1,NPR2,P2RY1,MAPK8,CCDC40,ARHGEF10L,FRMPD1,FUZ,HECW1,UNC5B,TROVE2,SLC44A1,RIMBP2,UBE3A,REEP1,NAV3,KCNAB1" Drug 488_DN iloprost; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "AMPD3,AMT,APBA2,APBB1,CDK10,PRX,ARNTL,ARSF,SLC4A4,AZGP1,RGS11,BAIAP3,CHRNB2,DNAJB5,ARHGEF6,PCYT1B,IFFO1,CPS1,ENTPD4,TMCC2,DYRK1A,EFNB3,SRPK3,VPS26C,RASL12,GAP43,COPS8,HPGDS,ATF7,SLC2A6,KCNQ3,MMP16,ADAM22,ENPP2,PLEC,PMS2,RETREG2,PRKCZ,MAPK10,RLBP1,DCUN1D2,GSTCD,RASA3,SHANK2,CRTC1,TEK,THBS4,SEZ6L,TUB,ZNF142" Drug 6461_DN Clioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASIC1,BRAP,PLA2G6,SEMA6A,MRTFA,APOC1,NUMB,ADAM15,BMP7,CA12,KRIT1,AP4M1,NRG2,CHD1L,SOCS5,PDE4DIP,DAPK3,DNM1,DTNA,TOM1,EFNA3,SCML2,MALT1,TXNL4A,DIDO1,BTN2A1,RNFT2,VWA5A,MAPT,NF1,NUCB1,OXTR,MINDY2,PTK2,RAB3A,RET,SEC61A2,SBF1,ITSN1,BCAN,SLC20A2,ZCCHC24,TROVE2,ITPRID2,TTBK2,ASTN2,MCF2L,TMOD1,ZNF189,SSPN" Drug 2542_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "TRMT9B,APC,FAM131A,CDK10,KIF1A,CACNA1I,CAPN3,SLC16A4,SLC4A7,CTNND1,SPOCK3,SV2A,CDON,FEM1B,ABI2,PLXNC1,MRNIP,LRRC23,RASGRP2,CDKL3,KAT8,GABRA2,SEPT9,ALDH1L1,MSL3,GRM1,GRM8,SLC2A6,KPNA5,MAPT,MYT1,PLCD1,FAM120C,KHDRBS2,RNASEL,MRAS,SLC1A7,SLC11A1,BTBD7,KDM4B,KDM4C,STX1A,VAMP1,EXOC7,TAL1,SYNE1,TNNT1,FLRT2,VIPR2,SYNC" Drug 4543_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SEMA4G,MTMR3,MAP7,SYNGR3,DNAJB5,CNTNAP2,SMG7,MRNIP,RGS17,ERCC2,SPEG,ACSL4,BAIAP2,SEMA4D,PNMA2,TRAF3IP2,GART,C1QL1,POLL,GPR17,ITPKA,KHK,KIF5C,L1CAM,MMP16,MT1M,ZNF862,NDP,PBX1,PLXNB1,RC3H2,SAMD9,KIRREL1,FBXW7,NCBP3,ATXN7,SCG5,ZFP30,SHANK2,SLC20A2,ZNF667,TNIK,SPART,MAPK8IP3,ASTN2,AHCYL2,TK2,FAM155A,LMF1,HPS4" Drug 6783_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADD2,ADORA1,BIN1,KCNAB2,EPB41L5,AQP4,ADAM15,BAIAP3,CACNA1D,CALB1,BRSK2,USP2,NEURL1,HAPLN1,SPOCK2,JAKMIP2,RUSC2,DNM2,ATN1,DYRK1A,VPS13B,LRRC23,ERCC2,EFS,OLFM1,FLNC,ZNF44,SIGLEC8,GCNT2,RAPGEF1,GRIK5,NR3C1,RNFT2,TJAP1,KCNJ5,CD200,MPP2,PGAM2,PTAFR,RAB3IL1,RGS12,ZFHX4,ASAP3,SLC1A7,PLCB1,ATP11A,PSD3,OBSL1,PLPPR2,SCG2" Drug 3561_UP Ciprofibrate [52214-84-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ACTN2,NDRG2,BIN1,ANK1,PPFIA3,ARHGDIG,BRINP2,ADGRB3,CACNA1I,CFAP410,RUNX1T1,CBFA2T2,TPP1,AATK,JAKMIP2,ATN1,CNNM1,EFNA3,EGFR,FGF1,GAD1,ERAP1,TMEM8B,ALDH1L1,GLS,ADAMTS13,GRIK5,NXPH3,HLF,HTR2A,KCNH2,ADAM22,NEUROD1,SLCO1C1,NOVA2,NTRK3,MAPK10,RAD52,TCP11L1,PPP1R9A,DOCK10,TNIK,SPTB,KAZN,WSCD1,CHST8,WIPF1,EMSY,GDPD5,STMN4" Drug 3835_UP Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ASIC1,KCNAB2,AQP6,BRINP2,ATP2B2,CACNA1I,CACNA2D1,CACNB2,CDH18,CDO1,CNTN1,ATN1,DTNB,EGFR,ELAVL3,EN2,RASGRP2,MTSS1L,IGSF6,TUBB4A,C1orf61,AGAP2,NSG1,SIGLEC8,C1QL1,ELOVL5,ICA1,ITPKA,KIT,NEUROD1,SLCO1C1,PDE1C,PLTP,POU3F4,PTHLH,KHDRBS2,KCNIP1,SCN8A,SELL,ZKSCAN3,LIMCH1,RBM34,SOX10,ARHGAP26,ZBTB43,TROVE2,TAC3,TBCEL,PIK3R5,XRCC4" Drug 1780_UP (-)-Cinchonidine [485-71-2]; Up 200; 13.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "ADORA1,C1QTNF3,SPOP,ARHGEF1,ARHGAP33,ZFYVE9,FAM189A2,COL9A2,CTIF,BRINP1,DCTN1,DNM2,MBNL2,RASGRP2,F5,PRKAG2,GLYR1,GLS,GRIK5,PADI2,MYO9A,NINJ2,NRGN,OCRL,PALM,PDE3B,PHKG1,RETREG1,DEF8,PTK2,BSDC1,ZNF671,ATXN1,AMBRA1,SLC6A8,SLC11A1,KBTBD4,MAPKBP1,TNIK,SPTB,THSD1,SS18,CAMSAP2,TNNT1,TNS1,TSC2,LAT2,ZNF142,MPPE1,ST7" Drug 6132_DN Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "KIDINS220,MTUS1,MRTFA,APBB2,NCOA1,SYNJ1,CAPN3,CAST,TAOK2,CREM,MICAL2,CSNK1E,RABGAP1L,PRKAG2,SRCAP,ZNF276,MSL3,POLL,IL6ST,MAP4,MID1,GIT1,OLR1,OMG,PIK3R1,NLE1,LRP12,PPARA,MAPK8,ZSCAN32,PEX5,ZNF493,TRIM68,SEC14L1,FAM214B,SLC11A1,ARFGAP1,WDTC1,KDM4C,SIN3B,TNS2,TEX15,PARD3,RBFOX2,HIRA,FLRT2,VIPR2,ZFP37,WNK1,NLRP3" Drug 2392_UP Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.90E-04 1.00E+00 3.24E-03 3.69E-02 50 199 "SLC12A5,AP2A2,SPARCL1,ALK,SYT13,ASPH,ZSCAN18,CFLAR,USP2,DGKI,HOMER3,ABI3BP,DGKG,DTNB,ST8SIA3,EFNA3,CELSR3,MTSS1L,PIPOX,TUBB4A,FECH,KIAA1109,SCARA3,FOXG1,ADAM28,GPR19,GRIK5,GRM7,ICA1,LAMA2,ADAM22,MYT1,NEK1,NF1,POU3F4,CNNM2,FAM120C,RGS3,NEK11,GALNT10,CNKSR2,ARHGEF40,SLC20A2,SOX10,PDLIM2,TCF7L2,SEZ6L,SSBP2,VGF,EMSY" Drug CID000000587 phosphocreatine disodium Stitch 3.95E-04 1.00E+00 3.28E-03 3.74E-02 35 126 "BRAP,AK2,ALAD,AMPD2,AMPD3,MADD,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CFLAR,LDHD,ENTPD2,SLC22A6,CS,AK5,DLG3,AK8,ATP2C1,GATM,GCK,MYBPC1,MYH6,OGDH,OPA1,P2RY1,PIK3C2A,PKM,PYGM,SLC6A8,IFT122,P2RY12,SLC30A4,GJC2" Drug CID000002156 amiodarone Stitch 4.18E-04 1.00E+00 3.47E-03 3.95E-02 42 160 "ASIC1,ADRB2,AGT,CFLAR,CACNA2D1,CALM1,ASIC3,CLTA,ABCG2,PLCXD3,MED12,PRKAG2,FOXG1,GALC,BRD8,PLCD4,GRIK1,TNFAIP8L3,KCNA1,KCNA2,KCNA4,KCND2,KCND3,KCNH2,MYH6,MYH7,MYL3,ABCB1,PLCB2,PLCD1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,PLCB1,TF,THRA,TRH,ZIC3,NETO1" Drug 1220_UP SAHA; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.18E-04 1.00E+00 3.47E-03 3.95E-02 42 160 "ABAT,ABHD6,ADRB2,ARNTL,ST3GAL5,ABCG1,PDE4DIP,CTH,DNAJC6,C2CD2L,PLPPR4,SRGAP3,EFNA3,RGS17,F3,TAOK3,BAIAP2,SORBS1,FYN,RND1,GUCY1B1,BACH2,DIPK1A,MAPT,MEF2C,MMP16,ODF2,PCDH9,PDGFRA,SERPINI1,RETREG1,PTCH1,RGS4,SH3GL3,KDM4B,TNIK,ARHGAP26,ELOVL4,RGL1,SYT1,TACC1,TGFBR3" Drug CID000065866 lercanidipine Stitch 4.20E-04 1.00E+00 3.48E-03 3.96E-02 21 63 "AGT,ANK1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG3,CACNG2,PKD1,RYR1,RYR3,TPCN2,NETO1" Drug CID000448864 hexadecyl octanoate Stitch 4.20E-04 1.00E+00 3.48E-03 3.96E-02 21 63 "CBS,KRIT1,CRLF1,TBC1D5,DBN1,GFAP,CNDP1,KCNK1,KCNK2,KCNK3,CAMK2N2,MEST,KITLG,NRGN,KCNK10,PLEC,PPP3CA,SLC12A2,SYP,TSC1,TSC2" Drug ctd:C076994 perfluorooctane sulfonic acid CTD 4.21E-04 1.00E+00 3.49E-03 3.97E-02 305 1630 "RALGAPA1,SERPINA3,ACADM,ACHE,ACLY,CLK4,ADORA1,ADRA1B,KIDINS220,OSBPL1A,OSBPL8,AK2,ALCAM,AMPD3,AMPH,CDC42BPA,GPAM,APOC1,APOC2,APP,MIER1,PPP4R4,TMEM263,ARHGAP5,ARNTL,PLA2G4C,STK33,ASPA,ATP1A1,ATP1A2,ATP1A3,ATP2B2,DOCK11,MPDZ,BCHE,IL33,CACNA1A,DDR1,CACNB2,CAMK2A,CAMK2G,CAST,CBR1,ZNF501,CCKBR,KRIT1,MTMR7,SCARB1,ARHGAP33,CDO1,CLGN,ADGRG1,SRSF11,CHM,CHRNB2,CLU,NGEF,FADS2,ABCG2,SULT4A1,NIPBL,COX4I1,MYRIP,CP,NECTIN3,CPS1,RBM39,NCOR1,ABCG1,CS,DZIP3,CTH,CTNND1,CTNND2,ZFYVE16,INTS1,SPOCK2,DBI,DBN1,ZEB2,SACS,MTX3,NR1D2,DMTF1,CASP8AP2,DRD1,EEF1A2,OPTN,PHF20L1,EGFR,AASS,KCTD3,ELAVL4,ENO2,RCAN2,ERBB2,F5,F8,ABCA8,FABP7,ACSL4,DLC1,ATP8A1,FDFT1,KIAA1109,FGFR3,POLK,ATP5PD,FOXO3,FLT1,SORBS1,SMC2,USP16,UFM1,CAMKK2,ZMAT1,STAG2,GAA,IQGAP2,GAP43,CPLX1,MYOZ2,GCK,ALDH1L1,GCNT2,GFAP,GFRA1,GFRA2,PPARGC1A,MALT1,KIRREL3,DHRS4,BRD8,GK,TNRC6A,GLUL,ZNF638,GOLGB1,GPD1,CNTRL,RAPGEF4,GRIA2,PLCD4,GRIN1,NR3C1,GSTT2,HBA1,ELOVL5,ACOT7,HMGCR,HP,HSD17B1,HSP90AA1,IGFBP1,LRRCC1,IL6ST,ITGAV,ITPKA,JAK2,KCNN2,KTN1,LIG4,PAXBP1,HECTD2,ARHGAP12,LSS,MAPT,MAT2A,MBNL1,MEF2C,MEIS1,MEST,MOG,ZNF680,NRBP2,ZNF92,MTTP,MYH6,MYH7,NCAM1,NDUFA5,NEK1,SLCO1C1,NFE2L2,ALDH1L2,NOS1,NUCB2,CLDN11,CNTN3,PC,PDE2A,PDE3A,PDE3B,ENPP2,ABCB1,PIK3R1,SNX10,XRN1,PKM,STRN3,POLG,PPARA,PPP1R1A,PPP3CA,PRKCB,PRKCG,MAPK3,MAPK8,GRAMD1C,PRPH,MASP1,SAMD9,VPS13C,PSMA6,PSMD13,PTH1R,PTK2,PTPRD,PTPRZ1,USP47,OXR1,ARID4A,REV3L,TTLL7,MRPS18A,SLC25A36,ZFHX4,CCDC82,LRRK2,LGR4,MEG3,ZNF354C,RXRG,CCDC112,AP1AR,RMI1,S100B,MAPK12,SATB1,SCP2,SH3BGR,KIF21A,HKDC1,CHD9,FNDC3A,SLC1A2,SLC1A3,CCDC88A,SLC15A2,SLCO1A2,SMARCE1,INAVA,KIF13A,SOX2,BDP1,ENKUR,UHRF1BP1L,SPP1,RBM26,PBLD,ITPRID2,ZNF302,SAMSN1,SSTR2,LARP4,SS18,SSPO,ERBIN,ADHFE1,MLC1,FGD4,VPS13A,SYN1,SYP,TCF4,ZEB1,TRIM2,WASHC4,TEK,TF,DICER1,CDH22,THRA,TJP1,ACTR6,TMOD1,TPM1,TRPC1,ANO5,TTPA,CCDC14,VSNL1,RICTOR,MICU3,KCNT2,ZNF540,ZNF138,SMARCAD1,EVI5,TRIM16L,GOPC,ZNF37BP,JMJD1C,SRGAP2B,SENP7" Drug CID003035668 7-Cl-Thio-Kyna Stitch 4.22E-04 1.00E+00 3.50E-03 3.98E-02 9 17 "B3GAT1,GLRB,GRIA1,GRIA2,GRIA4,GRIK1,GRIN2C,GRIN2D,TACR1" Drug CID000029642 S 254 Stitch 4.22E-04 1.00E+00 3.50E-03 3.98E-02 9 17 "ABAT,BOC,CDON,GAD1,GAD2,GFAP,RNASE1,SLC6A1,SLC6A11" Drug CID000156857 dihydroxyaflavinine Stitch 4.22E-04 1.00E+00 3.50E-03 3.98E-02 9 17 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2" Drug DB00897 Triazolam Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000126582 cyclobutylene AP5 Stitch 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug CID000190946 AC1Q5XN5 Stitch 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "CALM1,CCK,CCKBR,KRIT1,B3GAT1,TAC1,TACR1" Drug ctd:D010406 Penicillins CTD 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "CAMK2A,CLU,GRIA1,GRIA2,MT3,PLPPR1,SLC1A2" Drug DB00628 Clorazepate Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB00231 Temazepam Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB01595 Nitrazepam Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug DB00186 Lorazepam Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug CID000028123 tetrahydridoborate(1- Stitch 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "APAF1,CACNA1D,NECTIN3,CASP8AP2,NOS1,PMP2,SLC4A3" Drug DB00404 Alprazolam Drug Bank 4.33E-04 1.00E+00 3.58E-03 4.08E-02 7 11 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3" Drug 2452_UP Vigabatrin [60643-86-9]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.34E-04 1.00E+00 3.59E-03 4.09E-02 45 175 "NDRG3,GRAMD1B,BEGAIN,APBB2,CDK13,DNAH17,CFLAR,BMP7,INA,CD86,CD38,CHN2,COL9A3,CLOCK,CREM,ABCG1,SIPA1L1,CTNND1,DOCK4,ERBB2,KIAA1109,BAIAP2,PRKAG2,TRAF3IP2,NEU3,GNG3,AFF1,MMP17,MX1,NF1,OLR1,P2RY1,PDE4A,PDE4B,BCAS3,WDR25,PLPPR1,ITSN1,FRMPD1,SLC11A1,ATP10B,EPB41L3,WWC1,TPM1,ZBTB16" Drug 1166_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.34E-04 1.00E+00 3.59E-03 4.09E-02 45 175 "NDRG2,GRAMD1B,TRMT9B,APP,NCOA1,CFLAR,ST3GAL5,BTRC,CD86,COL9A2,CREM,MICAL2,SIPA1L1,KIAA0753,SGSM2,SIDT2,FAM13A,MBNL2,CAP2,OGA,LILRA2,NINJ2,KCNK10,PDE4B,PLCD1,PMP22,MBOAT7,PRKACB,PTPRN2,CEP97,HSPA4L,SLC1A7,SLC15A2,SNCA,FCHO1,RGL1,KIAA1107,TCF7L2,SZT2,TK2,RBFOX2,FLRT2,PARP11,PHTF2,FXR1" Drug 1161_UP SAHA; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.34E-04 1.00E+00 3.59E-03 4.09E-02 45 175 "ABHD6,ADD3,ADRB2,ALAD,APBB2,FAM131A,ST3GAL5,HIP1R,NMT2,STOML1,PREPL,CRY2,PDE4DIP,DOCK4,KIAA0513,RIMS3,DNAJC6,ANKRD46,EFNA3,ENO2,CDKL3,TESK2,PCYOX1,HBS1L,RND1,RAB40B,PADI2,IL11RA,KIF5C,NCAM1,SERPINI1,CCSER2,TMEM231,RPS6KA2,ANKRD6,PALLD,ZCCHC24,ZSWIM8,SPTAN1,CEP68,RGL1,STXBP1,CAMSAP2,RPGRIP1L,HEY1" Drug CID000001140 toluene Stitch 4.34E-04 1.00E+00 3.59E-03 4.09E-02 45 175 "ASIC1,ABHD6,LRRC7,LRRC4C,APP,AP4M1,CDO1,ASIC3,CHRNA4,DBT,LYPD1,AHCYL1,DNER,MSTN,GFAP,GPT2,GRIN2C,GRIN2D,HBA1,CDH20,MID1,MTTP,NDUFA5,NODAL,PAX6,ANLN,FXYD1,PRKCB,PRKCG,PKN2,PRKCZ,SUGCT,ROM1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,FAIM2,SCN3B,SP2,CLSTN2,LEFTY2,TNNT1,PDSS1" Drug 5640_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.38E-04 1.00E+00 3.59E-03 4.09E-02 46 180 "CFLAR,PLAA,CLCN3,ARMC8,PDE4DIP,DZIP3,KIAA0586,ZBTB24,RHOBTB1,ANKRD46,RBM12,EIF5,IRAK4,ARMCX1,SYT17,ITPKB,NAP1L2,PDCD2,PDE3B,PIK3R1,NLE1,ZSCAN32,RAD51D,ZCWPW1,RNASEL,ZC3H14,SUPT20H,ZFP30,FERMT1,SYBU,PAAF1,WDR37,SPATA7,ZNF302,CEP68,ZC3H4,ARHGEF9,ASTN2,FAM208A,TRIM2,ZMYND8,ZNF23,ZNF74,HPS4,MVB12B,ZNF248" Drug 5571_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.38E-04 1.00E+00 3.59E-03 4.09E-02 46 180 "ADORA1,ADORA2A,BIN1,CNTNAP1,APAF1,APC,ARRB1,DNAH17,N4BP2L1,CACNA1D,CACNG1,CAMK2B,SH2B1,AATK,TOX,DAPK1,DRD1,EDN3,EPB41L1,CACNG3,ZNF589,GLYR1,GRM7,KCNN2,PFKFB3,MAPK10,KLK6,RAP1GAP,RNASEL,MYH14,SYNDIG1,SMPD3,SELL,KANSL3,PKNOX2,SLC11A1,SLC22A4,AJAP1,WSCD1,TRIM2,DICER1,UCHL1,ZFP37,GDPD5,NAV2,AP3B2" Drug CID000446872 AC1L9K72 Stitch 4.38E-04 1.00E+00 3.59E-03 4.09E-02 68 292 "ACLY,ABHD6,PLA2G6,PITPNM2,ANK1,ANXA7,DGKZ,GPAM,DGKD,SPTBN4,PLA2G4C,ALDH7A1,BID,SPAG9,DGKI,LGI1,RAB33A,FADS2,HECTD1,CNTN1,PCYT1B,PLCXD3,DGKB,DGKG,PITPNC1,CHRDL1,EPB41,F3,PSD2,HRASLS5,ATP8A2,STARD10,PLCD4,GABARAPL2,MBP,NRGN,NUMA1,PCDH8,ABCB1,PLCB2,PLCD1,PLTP,MBOAT7,PTX3,PEX2,ATG16L1,ATP8B4,SMPD3,PEX26,CCDC88A,SLC12A4,ARFGAP1,SPTAN1,SPTB,SEPT8,ARHGEF9,PLCB1,TBL1X,DDHD1,PITPNB,SPHK2,PLPPR5,SLC30A4,SCG2,PLD4,PLSCR4,HRASLS,NETO1" Drug CID000092409 SKF89976A Stitch 4.39E-04 1.00E+00 3.59E-03 4.09E-02 13 31 "ABAT,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,NTRK2,SLC1A2,SLC6A1,SLC6A11,SLC17A7" Drug CID000073672 isoxaben Stitch 4.39E-04 1.00E+00 3.59E-03 4.09E-02 13 31 "CBS,CNOT8,EDN1,EDN3,EDNRB,RASL12,GFRA1,RAPGEF1,SEPT4,IRX1,RET,ARX,SOX10" Drug CID000000762 GTP - Na Stitch 4.40E-04 1.00E+00 3.59E-03 4.09E-02 183 925 "ABR,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,ADRA1B,ADRB2,KIDINS220,AP2A1,AP2A2,AP1B1,NME5,ARHGAP20,DOC2A,AMPD2,AMPD3,AMT,ARHGDIA,ARRB1,SEC11C,RGS9,CDK5R1,AP1M1,CACNA2D1,CALM1,KRIT1,CCNH,CCNT1,RGN,P2RX6,ARHGEF1,CDC42,COPB2,CHN1,CHN2,CHRM1,ARHGAP22,CLTA,CLTC,NGEF,MAP4K4,AKAP5,SEC24C,CSNK1E,CSNK1G3,GPSM1,HDAC9,ARHGAP32,ARHGAP24,MAGI2,RHOBTB1,DMD,DNM1,DNM2,SLC25A18,DRD1,DNM1L,EEF1A2,EEF1D,KLHL5,FAM13A,EGFR,RASA4,EIF4G1,EIF5,BSCL2,TUBD1,RASGRP2,ERCC2,RRAGB,TUBA1B,PTK2B,TUBB3,TUBB4A,SEC24B,POLR1B,SCARA3,AGAP2,NELFCD,RASL10A,ARFGAP2,CAMKK2,GAD2,IQGAP2,TUBA8,RAB40B,GNAL,GNAO1,GNAS,GNG3,GNG4,MCHR1,TUBA1C,RAPGEF4,RAPGEF1,GUCY1A2,GUCY1A1,GUCY1B1,ARHGAP36,MSL1,TUBB2B,ARHGAP12,MAG,KITLG,MT3,MX1,MYO5A,NCF2,NF1,NME4,NPY,NPR2,OCRL,OMG,PAH,PDYN,GNG2,PKM,GPSM2,POLG,POLR2F,PRKCB,PRKCG,MAPK3,KLK6,PTK2,QDPR,RAB3A,RASGRF1,RASGRF2,RGS10,RIT2,RNASE1,RPL15,RPL38,RPS20,MRAS,COPZ1,RPH3A,SIRT2,SLIT1,ARFGAP1,SNCB,ARHGAP26,SST,SSTR1,SSTR2,FGD4,SUPT5H,ABCC8,ARHGEF9,PLCB1,TAF6,MLST8,TAF9,TBL1X,TCEA1,ARHGAP9,DICER1,TIAM1,TRIO,TSC1,TSC2,TUBB2A,TUBB1,UBC,UBTF,PITPNB,VAV1,VAV2,VIPR2,XPO1,POLR3H,PRTFDC1,TUBA1A,NELFE,RTN4,NUP214,AAAS" Drug 3369_DN Rolitetracycline [751-97-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.40E-04 1.00E+00 3.59E-03 4.09E-02 47 185 "ASPHD1,MRTFA,EPB41L5,ARHGDIG,ATM,CFLAR,RCHY1,ENTPD4,RIMS3,GIT2,DBT,HP1BP3,RCAN1,MBNL2,ING4,FGFR1,OGA,ZNF44,GLYR1,FERMT2,GPD2,TDRKH,IL6ST,MBD1,MITF,ADAM22,ZNF862,NF1,CNOT4,SLC11A2,PDE3B,PIK3R1,RETREG1,STRN3,PMS2,SLC25A36,TRA2B,COA1,SNCA,EMC1,SS18,DMXL2,TRIM2,PCDHA6,TMPO,HIRA,SSPN" Drug 2551_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.40E-04 1.00E+00 3.59E-03 4.09E-02 47 185 "NDRG2,ADORA3,AMH,ANK3,DDO,PTCH2,SLC4A4,PROM1,CACNA1G,CACNA2D1,CAPN3,USP2,EPS15L1,ZFYVE9,CLCN4,CNTFR,NCOR2,DZIP3,RIPOR2,EXOG,DTNB,EDN3,FAM13A,CDKL3,CEND1,GAB1,GAD1,GSN,MMP16,OPCML,FXYD1,PTPRN2,ZFP2,SCG5,ASAP3,IZUMO4,ZC3H13,SAMSN1,AJAP1,ARHGEF9,DNMBP,CRTC1,TMOD1,RBFOX2,TRH,TUBB1,ZBTB16" Drug 3536_UP Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.40E-04 1.00E+00 3.59E-03 4.09E-02 47 185 "ADGRF5,AMPD3,ARNTL,DNAH17,CFLAR,ARHGEF2,CLGN,ADGRG1,FOXN3,STOML1,SOCS5,EDRF1,EXOG,DSCAM,DTNA,MBNL2,DMTN,FGFR1,SEPT9,INPP5K,GNG4,GRB10,ATXN2L,KLF12,ICA1,IL6ST,KPNA5,MPP2,ADAM22,BCO1,MX1,PHKG1,RIPOR1,TMEM206,RPS6KA2,PPM1E,SYBU,KANSL3,SMARCD3,ZNF415,KIF21B,TRIM2,PCDHA6,TK2,TRIO,UGT8,VLDLR" Drug 6895_UP 0297417-0002B [362658-29-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "NME5,APBB2,CDK13,ASPH,BACH1,IL33,SYNGR3,CRLF1,CACNA2D2,AKAP7,COL9A3,CREB5,CSF1,TBC1D5,SGSM2,RABGAP1L,ECM2,FCF1,OPTN,YAF2,KIAA1109,OGA,SEPT9,SRCAP,GNAL,SOX21,ITGA7,ITIH2,JAK2,KCNQ3,LSS,AFDN,MYO6,NEK1,CDK18,PDE4B,PDE4D,PFKFB2,RAD51D,CLIP1,TRAPPC13,FNDC3A,DZIP1,SOX15,TACR1,KIAA1107,ZBTB14,RNF146" Drug 6199_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "ASIC1,MTUS1,BIN1,APBB2,SLC4A4,NRP2,BTRC,CACNA2D1,HIP1R,MAGI1,FEZ1,PDE4DIP,SLITRK5,MFAP3L,KLHL3,PLPPR4,DYRK1A,MBNL2,MRNIP,ETV1,C1orf61,FERMT2,STON1,PCLO,KHK,MYO6,NCAM1,PFKFB2,CAMKV,CCSER2,PLCD1,CEP41,MAPK7,VPS13C,SYTL2,ITSN1,PPM1E,ANKRD6,SORCS3,TNIK,DBNDD2,ST5,MCF2L,TCF4,ATP13A2,KLC2,TRIM9,MAP3K12" Drug 6253_UP Ellipticine [519-23-3]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "ANK1,NCOA1,ADAM15,VAX2,QKI,ARHGEF6,CREM,CSF1,PDE4DIP,CTNND2,CDON,MBNL2,TNK2,HSD17B14,EN2,EPB41L1,LRRC23,BAIAP2,SCARA3,GAD1,B4GALNT1,GLS,SPACA9,PADI2,MAP4,NELL2,NF1,NPTX1,PDE4A,SERPINE2,RETREG1,PPP2R5C,PTCH1,C1orf54,SGK1,WDR47,SLC9A5,EFHD1,SNCA,ZCCHC24,CLSTN2,ARC,ATP11A,EXOC7,TPM1,TRPC1,PLPPR2,TIGD6" Drug 5623_UP Clioquinol [130-26-7]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "ASIC1,AMPD3,ANK1,CNTNAP1,DDX3Y,SLC4A4,ARHGEF2,FOXN3,ASIC3,CNTN1,IFFO1,CRMP1,VCAN,CNTNAP2,PHYHIP,CTIF,MAGI2,NTM,TMCC2,TOM1,EDNRA,TUBB4A,FGF13,FGFR1,ERAP1,SRCAP,RND1,GRM7,KCNN1,NOVA2,PAX6,PLP1,PLXNB1,PTPRD,SEMA6D,DOCK10,SLA,SLC11A1,KIF21B,TAC3,TAL1,WSCD1,DNAH7,TMOD1,SEZ6L,CHST5,VAV2,VLDLR" Drug 4099_UP Alprostadil [745-65-3]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "BEGAIN,PPP4R4,NRP2,SCAPER,MAP7,RAB33A,STOML1,CREM,AKAP12,PHF14,CTH,ARHGEF4,SPOCK2,C2CD2L,SPOCK3,SV2A,ARNT2,ATN1,EDIL3,ELAVL3,ATP8A2,GDF9,RUNDC3A,GPD2,CACFD1,SOX21,HAS2,HSD17B1,JAK2,KCNQ3,TM6SF1,MDM4,ADAM22,MX1,NF1,PBX1,SMOX,PTHLH,RGS4,KCTD17,CSRNP3,ZNF821,SLA,SS18,ARC,PSD3,NSD2,PHTF2" Drug 1421_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "NDRG3,ADD3,ARNTL,MARK4,CAPRIN2,ATP6V0A1,ST3GAL5,SCAPER,MTMR3,UBE2L6,DNAJB5,FEZ1,PPP1R16B,CX3CR1,ABI2,LPAR6,EPB41L2,EXTL2,FGFR1,ATP2C1,ADAMTS13,GSN,IFI16,ITGA7,ITGAV,KHK,KIF5C,VWA5A,MBD1,NRGN,CCSER2,RETREG1,GPSM2,TTC13,CCDC25,SATB1,ITSN1,WDR47,MAPKBP1,ZSWIM8,RGL1,STXBP1,SYT11,ARHGEF12,TP53BP1,RBFOX2,SSBP2,ITM2C" Drug 4563_UP Thiostrepton [1393-48-2]; Up 200; 2.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 48 190 "SLC12A5,FZD9,BCAS1,PDE8B,ASPH,RASL11B,ATP2B2,CADM3,SYNJ2,CACNA1I,CNTFR,TCEAL2,CREM,PDE4DIP,CNTNAP2,CTH,EDNRA,F5,REEP2,KAT8,SORBS1,GABRA2,RND1,MSL3,DIDO1,GRM8,PTGDR2,HPCA,IRF8,AFDN,PDE4D,PDGFRA,PFKFB2,SEPT4,LRRN3,PTHLH,SLC1A7,SLC6A9,RBM34,IQSEC2,MAPK8IP3,ADGRL3,SLC19A3,CHST5,VLDLR,LAT2,STMN4,JPH3" Drug 1943_UP Midecamycin [35457-80-8]; Up 200; 5uM; PC3; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ACLY,ADORA1,PLA2G6,ARNTL,CADM3,N4BP2L1,BMP7,MYRF,SPAG9,CHN2,DPH1,DTNA,EPB41L2,F3,AFF2,INPP5B,NCF2,NOVA1,SLC11A2,PC,FSD1,CYBC1,RET,RGS4,RNASE1,DCUN1D2,ATXN2,FHOD3,ZNF365,ARHGEF40,SLC12A2,ZKSCAN3,KDM4B,DOP1A,STXBP1,SYN2,SEMA4A,WSCD1,TCF4,TRIM2,ATP13A2,HEY1,TK2,BEX4,CA14,HIRA,PLPPR2,VIPR2,CLIP2,ZNF45" Drug 4797_DN Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ASPHD1,ABHD6,ADCY6,AP2A2,APC,EPB41L5,MTMR3,SOCS6,SH2B1,SDC3,DCAF8,DBT,PARD6A,ATN1,DTNA,SUGP2,TNK2,RGS17,ANKMY1,ERAP1,GART,GLS,ARHGAP19,DHX35,JAK2,KCNJ3,IPO5,MAP4,NCAM2,NOS1,SERPINE2,LRP12,PACSIN1,PPP2R2B,SAMD9,FAM120C,RGS10,TRAPPC13,ITSN1,ZKSCAN3,WDTC1,SOX2,EMC1,IQSEC2,DIP2A,TCF7L2,TRPC1,TSN,XRCC4,FZD3" Drug 6294_UP Aminohippuric acid [61-78-9]; Up 200; 20.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ASIC2,ADD2,ADGRF5,MRTFA,LGR5,PDE8B,CADM3,KIF1A,SYNJ2,CBFA2T2,NEURL1,LARGE1,LHX2,DNAJB5,CRMP1,FAM131B,DCT,CELSR3,PLXNC1,TENM1,ETV1,RRAGB,ZNF589,FGFR1,PDLIM5,GAB1,TRAF3IP2,HBS1L,POLL,STON1,LPAR4,SCIN,MBP,SCAMP5,NOVA1,PDE3B,PFKFB2,STRN3,CNNM2,RGS7,EMID1,ZFP30,DOCK10,PKNOX2,MYH15,PHLDB1,ARHGEF12,TK2,NT5M,KCNAB1" Drug 6225_UP Butacaine [149-16-6]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARID1A,ADCY6,AP2A2,SEMA6A,MRTFA,APC,PPFIA3,SLC4A4,ADAM23,ST3GAL5,CFAP410,NEURL1,B4GALT6,HOMER3,FAM149A,BAG4,GIT2,SPATA2,RABGAP1L,DMPK,DSCAM,SORBS3,RRAGB,F3,BAIAP2,GPR153,ZNF44,POLL,KCND3,MBP,MID1,NPTX1,SLC11A2,NRGN,CAMKV,SLC25A23,ZSCAN32,FAM120C,ACSM5,NKAIN1,RNASEL,GSTCD,KDM4C,ASTN2,TCF12,ZMYND8,VIPR2,LAT2,SCG2,MPPE1" Drug 4646_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "RALGAPA1,KLRC4,KIDINS220,MRTFA,AMPD3,EPB41L5,NRP2,KSR1,CACNA1G,HAP1,LARGE1,CHGA,NRXN3,COL9A3,IFFO1,SUSD5,NOS1AP,MFAP3L,AK5,EDN3,ABCA8,KIAA1109,FYB1,DKK3,GAD1,ALDH1L1,KCNF1,KCNN1,ADAM11,LYRM9,MYH7,NCAM1,NEFM,NF1,NOVA1,NTRK3,PTAFR,KHDRBS2,TCP11L1,MRAS,SH3BP2,SLA,KIF21B,HECW1,TAL1,SLC44A1,SEZ6L,FLRT2,NT5M,KCNAB1" Drug 453_UP "indomethacin, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "NDRG2,PLA2G6,ALCAM,PPFIA3,ASCL1,FUBP1,MTMR2,P2RX6,CNTFR,AATK,CSF1R,ATN1,SIDT2,EFNB3,EGR3,MRNIP,DMTN,TUBB4A,POMT1,ZNF276,ADAMTS13,CACFD1,IGSF1,JAK2,KCNB1,PACRG,TM6SF1,AFF1,NF1,NRGN,PCDHGC3,PDE1C,PIK3CD,RETREG1,POLG,FSD1,RGS3,RNF220,RNASEL,TCP11L1,FOXRED2,ATXN2,AMBRA1,TMCC1,SON,ZHX3,SSTR2,TIAM1,CADM1,SLC17A7" Drug 6612_DN Palmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "NME5,APC,KIF1A,CACNA1A,RAB28,HOMER3,IQCK,WHRN,HINFP,NCOR2,CDON,ATN1,SIDT2,SORBS3,STX2,TRMO,CINP,DENND2A,GAD1,INPP5K,C1QL1,CRCP,POLL,GPM6B,IL6ST,MAP4,MAPT,SCAMP5,AFDN,ZNF862,NF1,NUMA1,STRN3,SAMD9,RAD52,SEC61A2,RPS6KA2,ASAP3,ZNF415,SYT1,ATP11A,SYNE1,AHCYL2,THRA,TIAM1,CABIN1,METTL3,TRIO,TFIP11,VPS35L" Drug 1666_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ALAD,ALCAM,AMPD2,AMT,APOC1,APP,CDK10,RIPK1,KIF1A,BCL2L2,MTMR2,BTRC,CRLF1,SOCS6,TAOK2,PLAA,SLC4A8,CTNND2,DCAF8,HDAC4,MAML1,CNNM1,SIDT2,FGFR1,SYT17,INPP5K,SRCAP,GPR19,INPP5B,MAP4,NFYA,NPR2,SLC11A2,NUMA1,PDE3B,PLXNB1,RGS10,ABLIM3,PEX26,MAPKBP1,WDTC1,VAMP1,EXOC7,TCF7L2,TMEM121,TIAM1,VAV2,REEP1,GDPD5,URM1" Drug 1368_UP Diazoxide [364-98-7]; Up 200; 17.4uM; HL60; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "AP1B1,PKP4,APAF1,SLC4A4,EIF4G3,N4BP2L1,BMP7,CAMK2B,SRSF11,HDAC9,DCAF8,ZNF337,G3BP2,DTNA,VPS26C,GAP43,GNAS,CELF3,AGFG1,MAP4,NCF2,NELL2,OMG,CDIP1,RETREG2,C1orf109,PTX3,RAB3IL1,PAQR6,CLIP1,ATXN2,SEC14L1,STUM,ELMO2,SLC22A4,MAPKBP1,WDTC1,ZSWIM8,BEX1,KIF1B,WWC1,TCF4,TCF7L2,SPX,R3HDM1,RBFOX2,CADM1,VGF,GDPD5,AAAS" Drug 3866_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "APLP1,ASPH,RASL11B,ATP2B2,ADAM23,USP2,CACNA2D2,GPR37L1,STOML1,FADS2,SULT4A1,PICK1,WHRN,CRY2,RIMS3,TMCC2,DRD1,EFS,SPEG,AFF2,C1QL1,GPER1,SPACA9,DHX35,IRF8,KHK,TM6SF1,MEF2C,AFDN,ADAM22,OPRL1,CLDN11,SNTG1,PGAM2,PNMA3,PACSIN1,PLPPR1,FAM120C,HKDC1,PKNOX2,SPTB,ARC,KAZN,DOCK9,HEY1,PIK3R5,CHST5,TRIO,SLC30A3,SLC17A7" Drug 2075_DN Pindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "KCNAB2,LHX2,VCAN,PPP6R2,GPRASP1,SNPH,RABGAP1L,DNM2,FEM1B,SIDT2,EGFR,COQ7,SCML2,SEMA4D,CSPG5,SYT17,ZNF276,GNAS,GPD2,PCLO,AGFG1,DIPK1A,INPP5B,MX1,ODF2,KCTD15,CNNM2,SAMD9,APTX,PTPN13,ATG16L1,RGS10,MAPK12,SH3BP2,PEX26,BTBD7,COA1,POGZ,FBXW11,SATB2,PSD3,DICER1,METTL3,HIRA,FAM155A,NPDC1,ZBTB14,TFIP11,HPS4,MPPE1" Drug 6349_UP Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "BIN1,SEMA7A,SEMA4G,PPP4R4,ARRB2,DNAH17,SCAPER,LARGE1,RCBTB2,B4GALT6,AKAP7,ENTPD4,CNTNAP2,ARHGAP24,MFAP3L,AK5,DTNA,IRAK4,EZH1,FGFR1,SCARA3,FOXG1,CSPG5,RUNDC3A,GLYR1,GPM6A,GPER1,CACFD1,KCNJ5,NF1,NTRK2,NUMA1,PAK3,PLCD1,MAPK8,PROX1,GON4L,ROM1,KIF16B,SLC1A7,SLC9A5,SLC11A1,CEP68,EXOC7,TBCEL,TRIM2,UCHL1,VGF,WNK1,SEMA3B" Drug 2769_UP Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARID1A,ADD2,ALCAM,LTBP4,MRTFA,CDK13,MARK4,CFLAR,ST3GAL5,SYNJ2,MTMR3,CACNA1I,CACNG1,KALRN,ARHGEF1,TENM4,OSBPL3,HP1BP3,CDON,SNX29,FER,FHL1,KHDRBS3,SRCAP,GFER,GPM6B,PTGDR2,ELOVL5,IL6R,MAP4,MGAT3,MID1,AFF1,ADAM22,SLCO1C1,OPCML,P2RX7,SNTG1,PTHLH,ELOVL2,C1orf54,ZDHHC14,RGS3,CLSTN2,SAMSN1,NCDN,VAMP1,POPDC3,EXOC7,CRTC1" Drug 6518_UP Enilconazole [35554-44-0]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "AP2A2,AQP4,ASPH,N4BP2L1,SYNJ1,BTRC,CACNA2D1,CALB2,CLGN,GPR37L1,PLEKHB1,TAOK2,CNTFR,VCAN,CNTNAP2,GREB1,RASSF2,SPOCK2,GIT2,HP1BP3,EFNA3,SIGLEC8,GNAO1,GRM8,INPP5B,KCNC1,MAN2A2,MGAT3,NF1,NECAB2,PRKAR1B,PTX3,CCDC40,RAD52,FBXW7,KCNIP1,SLC1A2,SNCA,CAND2,ARHGAP26,POPDC3,SMG6,TRIM2,TLR4,TRH,AMACR,WNT7A,FTSJ1,ADAMTS9,JPH3" Drug 5750_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "RALGAPA1,AP2A2,C1QTNF1,CDC42BPA,PPFIA3,SLC4A4,BTRC,B4GALT6,RAB28,TCEAL2,ENTPD4,NCOR1,CSF1,DZIP3,SORBS3,PLEKHO1,FAM49B,PNMA2,GLRB,GNG3,GPM6B,TDRKH,GPER1,KLF12,IL12A,INPP5B,KCNH2,KIF5C,MAPT,MX1,ZNF862,ODF2,PTPRN2,PEX5,KCTD17,IL17RB,LIMS2,KBTBD4,DOK5,PHLDB1,STX1A,COBL,DNAH7,CABIN1,HIRA,VGF,WIPF1,NDRG4,MAP3K12,KCNAB1" Drug 5465_UP Pivampicillin [33817-20-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARHGDIG,MARK4,PTCH2,ATM,ARHGEF7,MTMR2,BTRC,HAP1,ADGRG1,FOXN3,IFFO1,MFAP3L,MBNL2,RASGRP2,EPHB1,STX2,ACSL4,PDLIM5,ERAP1,NR3C1,PADI2,VSIG4,DHX35,IL6ST,KHK,MDM4,ZNF862,SLC11A2,PDE1C,GPR85,PLTP,CCDC40,MYH14,WLS,PPP1R9A,SH3GL3,FBXO11,ELMO2,SLCO1A2,CXXC4,KDM4B,CLSTN2,ARHGEF9,DOCK9,RUNDC3B,ZKSCAN5,BEST1,ZIC3,EVI5,NUP214" Drug 2200_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "BCAR3,CDC42BPA,APBB2,CDK10,ZSCAN18,BTRC,CFAP410,CACNA2D1,THSD7A,CAMK2B,NMT2,PDE4DIP,EDRF1,ARHGAP24,BRINP1,DCT,SV2B,TRAPPC9,EDNRA,SORBS3,HSD17B14,FGF12,IQCG,GPR153,ZMYND11,SIGLEC8,ALDH1L1,GPM6B,GRM2,SCRG1,TJAP1,MKLN1,PLCL1,POU6F1,LRRN3,PPP3CC,BCAS3,FAM120C,MYH14,PREX2,EPN2,SMTN,SLN,EMC1,ZC3H13,CDK19,ATP10B,TCF4,AMACR,ZNF225" Drug 4076_DN Propylthiouracil [51-52-5]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "CDC42BPA,APBB2,APC,PDE8B,ASTN1,ALDH4A1,ALDH7A1,ADAM23,RAB28,RAB26,NCOR2,PDE4DIP,EDRF1,BRINP1,SMG7,SUGP2,EIF4G2,DMTN,ZNF549,ETV1,DLC1,ST3GAL6,ZNF44,SEPT9,GRM1,MAPT,MGAT3,MOBP,ODF2,PDE4B,SAMD9,ZSCAN32,FAM120C,IL17RB,DZIP1,PREX2,IQSEC2,ROBO3,ADGRL3,RPGRIP1L,PCDHA5,TIAM1,R3HDM1,TNS1,TRIO,ZMYND8,HIRA,OSBP2,TRIM9,TIGD6" Drug 1281_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ABHD6,NDRG2,MTUS1,TRMT9B,CDC42BPA,GAS7,CDK10,CFAP410,CAMK2G,INA,NMT2,CREM,DCAF8,SPOCK2,SGSM2,TRAPPC9,SEZ6L2,CNNM1,PLXNC1,FOXG1,CGREF1,SRCAP,SLC2A6,MAP4,MEF2C,GIT1,MYH7,PDE4D,PENK,CNTLN,PTAFR,RFX2,RASA3,ITSN1,MYH15,KDM4B,WDTC1,DOK5,IZUMO4,KDM4C,MAPK8IP3,DNMBP,TCF7L2,SZT2,THRA,PIK3R5,TPD52,SMUG1,ZMYND8,PLPPR2" Drug 7475_DN Trapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ASPHD1,AK2,BCAS1,CFLAR,ST3GAL5,C5,TAOK2,SMARCAL1,LRIG1,CTNND2,HDAC4,DAPK3,GIT2,FBXL5,COQ7,EZH1,CGREF1,GALC,MALT1,ZNF276,GPR19,GRB10,HMGCL,KCNF1,LIG4,MEIS2,MYO9A,OGG1,PPP3CC,PRKAR1B,LRRC49,SUSD4,RGS12,RNASEL,FERMT1,FNDC3A,NUBPL,EPN2,SON,ZBTB43,SS18,PHLDB1,TCF7L2,CHST8,HEY2,CABIN1,ZBTB14,MPPE1,ACTR3B,SSPN" Drug 1237_DN fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARRB2,SLC4A4,BCHE,CA12,CCNT1,SOCS6,QKI,CNTNAP2,FAM169A,DZIP3,KIAA0586,DBT,KIAA0753,LYPD1,PARD6A,KBTBD11,EFNA3,SPEG,ATP8A1,FGF1,TRMO,CGREF1,GLRB,PRRC2B,GPR37,GUCY1B1,MAN1B1,HSF2,MATN3,MEIS1,NASP,NDP,LRP12,PTPA,PRPH,FAM120C,RAD51D,ASAP3,SLC1A3,SPTAN1,TROVE2,CAMTA2,COBL,KAZN,KIAA1107,WWC1,TCF7L2,LAT2,EVI5,EPM2A" Drug 3352_UP Propantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ADORA1,KIDINS220,NME5,SYT13,RASL11B,N4BP2L1,SLC24A2,DNAJB5,RIMS2,DAPK3,SPOCK2,DNAJC6,DRP2,ABCC9,SNX29,TENM1,DMTN,AGAP2,FLNC,FOLR2,SEPT9,ATP8A2,ADAMTS13,GRIK5,SOX21,KLF12,IRF8,SHISAL1,KCNF1,KIF5A,KIFC3,MAOB,MGAT3,SLCO1C1,CDK18,PDE3B,PIK3CD,LRP12,GDPD2,C1orf54,TRIM68,SLC30A10,SFPQ,ASAP3,CNKSR2,SLC9A5,KDM4B,SSTR1,TBCEL,TUB" Drug 7166_UP Tomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "NME5,LTBP4,ASPH,AZGP1,GYG2,BAIAP3,COL4A5,LYPD1,CDON,DRD1,DSCAM,RCAN1,MBNL2,DMTN,RASGRP2,NRN1,BAIAP2,FHL1,EFCAB2,CGREF1,SLC2A6,ITIH2,KCNJ5,KPNA5,LIG4,TM6SF1,MPP2,ZNF862,NPTX1,PDE1C,LRP12,MAPK7,TMEM231,ZCWPW1,KHDRBS2,SYBU,EPN2,WDTC1,ZCCHC24,CLSTN2,AJAP1,SEMA4A,ROBO3,CDK20,TRPC1,VLDLR,ZBTB14,SYNC,PRDM2,SSPN" Drug 5927_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "KIDINS220,TRMT9B,BIN1,SEMA7A,APBB2,PPFIA3,CADM3,CDK5R1,CACNA1I,BAIAP3,SCARB1,PLEKHB1,TAOK2,FADS2,DNAJB5,WHRN,BAG4,AKAP12,CSF1R,DAPK3,MFAP3L,G3BP2,DMPK,EFNA3,EN2,ERCC2,ACSL4,BAIAP2,IQCG,PDLIM5,GABRA2,COPS8,GNG4,HNMT,KCNH2,LRP12,RAB3A,LIMS2,ELMO2,ZHX3,SS18,NSFL1C,KAZN,TBCEL,TRIM2,TPD52,NSD2,SPHK2,SH3GLB2,GDPD5" Drug 5679_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ACTN2,NDRG2,C1QTNF3,GAS7,DDO,SEMA4G,SLC4A4,SGCE,CALB1,FOXN3,TPP1,MYRIP,IPCEF1,PDE4DIP,ARHGEF4,EDRF1,GIT2,DCC,DMD,EFNB3,NCALD,SPEG,FABP7,AFF2,DCTN2,OGA,DISC1,LYVE1,GRIA1,GRM1,KCNH2,NTRK2,NECAB2,RELN,ASAP3,PREX2,BTBD7,SP4,PEG10,ZC3H13,TRIM2,SYNE1,HIF3A,DICER1,TK2,HEY2,PIK3R5,WIPF1,ANKS1B,ADAMTS9" Drug 6005_DN Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "AP2A2,TRMT9B,ANK3,APC,ARHGDIG,PDE8B,ASPH,NCOA1,ARHGEF7,CREM,PDE4DIP,FAM169A,GREB1,EDRF1,DCAF8,DBT,ZNF804A,RABGAP1L,EDNRA,SIDT2,EPB41L1,STX2,ACSL4,BAIAP2,GABRA2,GAD1,USP19,GLYR1,CNTRL,HNMT,IL6ST,IPO5,ZNF862,NF1,LRP12,PTN,FAM120C,RGS10,RNASEL,MRAS,ZHX3,SPART,IQCE,ATP13A2,CHST8,VIPR2,ZNF711,GDPD5,HPS4,KCNAB1" Drug 591_UP "N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Up 200; 20uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARID1A,ADD2,NCOA1,EIF4G3,ATP2B1,CBFA2T2,TBRG4,JAM2,ENTPD4,PPP6R2,TBC1D5,RIMS3,DAPK3,FEM1B,EPB41L1,GPHN,FGFR1,TRMO,NCKAP1,SEPT9,LILRA2,CLASRP,ICA1,KCNJ5,KIF2A,MAPT,MBP,NELL2,NFYA,NNAT,NPPA,PBX1,CAMKV,MAPK3,PRODH,PRPH,SBF1,SH3BP2,AMBRA1,WDTC1,EMC1,ZBTB43,NXT2,CEP68,EXOC7,WSCD1,TRPC1,DNAJC12,WNT7A,PRDM2" Drug 377_UP celecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ACTN1,NDRG3,ALCAM,CASK,ALDH4A1,BCL7A,KRIT1,DLGAP1,AKAP7,MICAL2,ARHGEF4,GIT2,KLHL3,SMG7,DSCAM,SGK2,TNK2,OLIG2,ERBB2,ERCC2,SEPT9,GART,GPM6B,GRB10,BTN2A1,NXPH3,HMX1,KTN1,MPP2,NPPA,OMG,SNTG1,PALM,PDE4B,POLG,PROX1,RAD51D,GSTCD,SATB1,SH3BP2,SLC1A3,KBTBD4,SMARCD3,TSPYL2,NSFL1C,SMUG1,CADM1,PLPPR2,MAP3K12,GDPD5" Drug 5219_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ASIC1,ACTN1,SLC12A5,APBB2,APC,PPFIA3,PDXK,ASPH,CBFA2T2,ARHGAP33,CDH18,CLGN,FOXN3,CHRNA4,FADS2,QKI,CSF1,ARHGEF10,DAPK1,ARMCX2,CDON,EDNRA,RBM12,FECH,AMOTL2,POLL,GPER1,JAK2,NCF2,NOVA2,MAPK10,SNRK,WDR25,RGS12,PPP1R9A,SMTN,KIF13A,PEG10,ZC3H13,IQSEC2,INKA2,MAPK8IP3,IQCE,TMOD1,CHST5,RUNDC3B,TRPC1,TRPM2,ITM2C,HRASLS" Drug 2165_DN Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ABHD6,DOC2A,APC,ADAM23,BCL2L2,SYNJ2,CACNA1A,HIP1R,PLAA,TMEM184B,SLITRK5,RIMS3,SPATA2,TRAPPC9,DTNB,DYRK1A,EFNA3,CELSR3,RASGRP2,CDKL3,PDLIM5,SEPT9,GLYR1,POLL,GNG4,STON1,DIDO1,MOBP,GIT1,MX1,NOS1,TREM2,PLCD1,PLTP,PMP22,POU6F1,SIDT1,PTPRN2,RAD52,SEC14L1,ZNF821,GALNT10,ANKRD6,ZCCHC24,UNC5B,TROVE2,PLCB1,ZBTB38,UBE3B,PHTF2" Drug 5311_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "C1QTNF1,PLA2G4C,SLC4A4,STX16,KIF1A,BMP7,KYAT1,CRY2,MICAL2,PDE4DIP,GREB1,ARHGEF4,SRGAP3,SORBS3,HSD17B14,F3,BAIAP2,PRKAG2,AHDC1,GLYR1,ATXN2L,HNMT,ICA1,LSS,MAP2,GIT1,LYRM9,CNOT4,NTRK2,P2RY1,PDPK1,WDR25,SYBU,SLC6A8,SLC20A2,SLN,KDM4C,FCHO1,EXOC7,TNS2,PLPPR2,LMF1,ZNF24,UPF3A,WNK1,PMEPA1,MAP3K12,GDPD5,HPS4,PCBP4" Drug 6502_UP Denatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ARID1A,NDRG2,AK2,GAS7,APOC1,ARHGDIG,ATM,ADAM23,SYNJ2,HIP1R,CHGA,QKI,CSF1R,PDE4DIP,ARHGEF4,MFAP3L,HP1BP3,SPOCK3,HS3ST2,ATN1,MBNL2,TUBB4A,GCNT2,HAS2,PTGDR2,KCND3,PACRG,MEF2C,AFDN,ADAM22,NEUROD1,NF1,OPCML,PCDH9,STRN3,LRRN3,GRAMD1C,PRPH,PTX3,TRIM68,SBF1,STUM,FRMPD1,PPP4R3A,KAZN,EXOC7,WSCD1,PSD3,SLC30A3,PLSCR4" Drug 436_UP HA-1077 dihydrochloride; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ASIC1,KDM5D,BRAP,AP1B1,LTBP4,APC,ARNTL,BMP7,BAIAP3,CAMK2A,CHN2,CNR1,ARHGEF10,SPATA2,KBTBD11,EFNB3,ING4,C3orf18,ZMYND10,FCGRT,FGF1,DCTN2,POMT1,FAM49B,SHISAL1,KCNK3,KHK,MEF2C,NNAT,NOS1,NOVA2,NTRK2,PFKFB4,RC3H2,PACSIN1,TMEM104,MTMR10,PTPRN,RNASEL,GSTCD,ASAP3,SLC9A5,SPART,DMXL2,PSD3,TNS1,SEZ6L,VIPR2,MPPE1,AAAS" Drug 7544_DN CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ADORA1,EPB41L5,APP,EDRF1,ARMCX2,ATN1,EGFR,SORBS3,LRRC23,CDKL3,EZH1,FAM49B,HBS1L,NCKAP1,POLL,CNTRL,MAP4K5,IRAK3,RASSF8,ARHGAP19,NF1,NFYA,CCSER2,PLCD1,SNRK,FAM120C,TMEM231,RAD51D,GTDC1,RGS12,MYH14,LGR4,SH3BP2,SLC22A4,LIMCH1,RBM34,CLSTN2,SS18,TTBK2,PLCB1,TGFBR3,THRA,TRPC1,ZKSCAN5,VGF,VLDLR,LMF1,SPHK2,EPM2A,TIGD6" Drug 2077_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "KIDINS220,MTUS1,AMPD2,APBB1,SEMA4G,CDK13,ASPH,ATM,ADGRB2,SYNJ2,NEURL1,GPR37L1,RAB28,CLTB,CNTNAP2,DCAF4,DAPK3,GIT2,DLG3,EXOG,CDON,DTNB,MAMLD1,EFNA3,IRAK4,MFSD10,COQ7,ANKMY1,BAIAP2,GAP43,SPACA9,CACFD1,ICA1,INPP5B,MX1,ZFYVE21,PLEC,PLXNB1,PKNOX2,ZNF415,IQSEC2,LHPP,MCF2L,EXOC7,NSD1,ATP13A2,CABIN1,LAT2,NSD2,AAAS" Drug 1683_UP Carbamazepine [298-46-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "PLA2G6,AMPH,GAS7,APLP1,MARK4,ATP6V0A1,ADAM15,ARHGEF2,FOXN3,RAB28,ZFYVE9,ABCG1,ATRNL1,EDRF1,NOS1AP,LYPD1,CDON,SORBS3,COQ7,NCALD,F3,TUBB4A,FHL1,CGREF1,GAD1,HBS1L,GAP43,SRCAP,GFER,GSTM5,INPP5B,LYRM9,NEUROD1,RETREG1,PPP5C,GSTCD,PPP4R3A,SLC15A2,USP33,PLCB1,TCF7L2,CABIN1,PIK3R5,TRPC1,TRPM2,RPRM,LMF1,ZIC3,REEP1,HPS4" Drug 5395_DN Aminophylline [317-34-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "C1QTNF3,DOC2A,APOC1,APP,BRINP2,CFLAR,HOMER3,BAG4,CREM,CRY2,SIPA1L1,PDE4DIP,TBC1D5,JAKMIP2,C2CD2L,LYPD1,TRAPPC9,MRNIP,EML1,IQCG,TRMO,AHDC1,GLYR1,GPER1,GRIK5,HNMT,ICA1,IPO5,MDM4,MITF,RETREG1,LRP12,PRKAR1B,PTHLH,ELOVL2,RAB3IL1,SH3BP2,FNDC3A,SLC1A7,EPN2,SPTAN1,THSD1,SS18,TTBK2,PLCB1,TCF7L2,RUNDC3B,VAV2,LMF1,SSPN" Drug 2459_UP Nitrofural [59-87-0]; Up 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 50 200 "ACTN2,ADORA1,CDC42BPA,LGR5,N4BP2L1,KIF1A,BMP7,CACNA1I,CDH2,ZFYVE9,STOML1,CREM,DAPK1,HIPK3,MBNL2,MRNIP,RASGRP2,KAT8,OLFM1,GNAL,GPM6B,GRM7,KLF12,ACOT7,HSF2,AFF1,P2RY1,TREM2,PGAM2,PIK3CD,PLCD1,PLP1,PLXNB1,PKN2,GDPD2,PTN,PTPRN2,PID1,ARHGEF40,ZC3H13,ATP10B,CLSTN2,NXT2,DMXL2,RPGRIP1L,RBFOX2,ZMYND8,TUBB1,ZBTB16,KCNAB1" Drug 4495_DN (-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ACTN1,ADRB2,PLA2G6,APC,CDK10,KIF1A,ADGRB2,SCAPER,CRY2,AATK,SNPH,ARHGAP24,SIDT2,DMTN,FGF1,CSPG5,GAD1,DISC1,GBX2,C1QL1,RNFT2,IL11RA,KCNJ5,MAPT,MEF2C,MT1M,LYRM9,PBX1,WDR25,RIPOR1,FAT4,ROGDI,SUGCT,ATXN2,FAM102A,ASAP3,BTBD7,KDM4B,IQSEC2,COBL,KAZN,EXOC7,TEX15,TNS1,WNT7A,NPDC1,XRCC4,ZNF74,NAV3" Drug 7394_DN Cefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "BIN1,ANK3,APBB2,MARK4,SYNJ2,MYRF,CHM,NIPBL,HOMER3,BAG4,HINFP,DZIP3,KIAA0513,GIT2,DLG3,CDON,EDNRA,SORBS3,EN2,ZNF589,TRMO,FAM49B,GART,GPD2,IFI16,JAK2,KIF5C,PFKFB2,POLG,MAPK7,RALGDS,RGS10,SEC61A2,TCP11L1,SHANK2,ELMO2,LIMCH1,FNBP1,ZBTB43,SEPT8,DNMBP,TRPC1,MICAL1,XRCC4,ZBTB14,MAP3K12,NT5M,NAV3,FZD3" Drug 166_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "AMT,SEMA7A,KCNAB2,APBB2,PDXK,BMP7,RAB29,CAMK2G,NEURL1,TPP1,NIPBL,CNTFR,IFFO1,NCOR2,TBC1D5,ACOT8,SUGP2,TUBD1,ETV1,FGFR1,FGFR3,CRCP,GLUL,ADAMTS6,ATXN2L,HMGCR,MBP,NFYA,SLC11A2,NRCAM,NTRK3,NUMA1,CAMKV,CNNM2,PTAFR,PAQR6,CLIP1,ASRGL1,SH3BP2,SLC1A7,ZKSCAN3,HECW1,SRPK2,SS18,NSFL1C,TCF7L2,VGF,NDRG4,REEP1" Drug 5401_UP Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "BBOX1,MRTFA,GAS7,MPDZ,CACNA1I,CACNA1G,BAIAP3,CAMK2G,INA,CBFA2T2,CHN2,CLCN4,AKAP7,SDC3,DNAJC6,DMPK,DTNA,EFNB3,PLEKHO1,CAMSAP1,FHL1,KHDRBS3,USP19,GNG3,CNTRL,HPSE2,KCNJ3,MYO7A,PDE3B,LRP12,RELN,PRR5L,SH3GL2,CPEB3,SNCA,KDM4B,DOK5,ZHX3,SAMSN1,PLCB1,SYP,ATP11A,GPR161,HEY1,LAT2,SPHK2,WNK1,KCNAB1,PARP11" Drug 4961_DN "Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "PPFIA1,APOC1,ASPH,STX16,ARHGEF7,SCAPER,MTMR2,WASF1,ZMYM4,CLU,NIPBL,CREM,FEZ1,DTNA,PLEKHO1,ACSL4,TXNL4A,NUDT21,CNTRL,BTN2A1,IGSF1,ITPKB,MAPT,MBNL1,MDM4,KITLG,GIT1,ZNF862,NF1,NFYA,OCRL,PDE4A,PLCD1,RETREG2,MBOAT7,PPP2R5C,PTHLH,CEP97,ZCWPW1,BTBD7,SLC22A4,TROVE2,EXOC7,BEX4,KAT6B,TRIO,NDRG4,REEP1,PRDM2" Drug 4249_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADRA1D,TRMT9B,APBB2,APC,APOC1,SEMA4G,MARK4,ADGRB2,NRG2,VCAN,ATN1,DTNA,TOM1,EDN1,MBNL2,ANKMY1,TUBB4A,ST3GAL6,CGREF1,ZNF44,RUNDC3A,GPR75,POLL,GRM1,KCNMA1,LSS,MATN3,AFF1,ODF2,OGG1,PBX1,PTPRN2,FAM120C,RAB3IL1,ZCWPW1,SEC61A2,SBF1,FRMPD1,KANSL3,RBM26,CEP68,SYT1,THRA,TIAM1,TSC2,OSBP2,CLIP2,EVI5,SEMA3B" Drug 3455_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ASIC1,APBB2,ALDH4A1,LDLRAD4,CACNA1D,NEURL1,SEPT7,ASIC3,STOML1,LY86,PICK1,AKAP7,ENTPD4,CSF1,SDC3,TMCC2,EFNA3,RND1,GPM6B,STON1,KCNN2,KIF5A,KIT,MAP4,MITF,ZNF862,NF1,NOS1,NUMA1,MED1,ATG16L1,KHDRBS2,GTDC1,ROM1,TCP11L1,SUPT20H,PPP1R9A,BTBD7,ZHX3,IQSEC2,PHLDB1,ARC,SYN2,ZEB1,CRTC1,VGF,VLDLR,SLC30A3,KCNAB1" Drug 5631_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NDRG2,MRTFA,BIN1,APC,CFLAR,MTMR3,CACNB2,CBFA2T2,CLGN,SLIT2,STOML1,QKI,CRY2,SIPA1L1,JAKMIP2,DSCAM,TOM1,EFNB3,MRNIP,F3,CAMSAP1,SCARA3,PRELID3A,GART,GLYR1,GRB10,RASSF8,INPP5B,MAP4,ZNF862,EPN1,PPARA,MED1,PRPH,PTCH1,NKAIN1,KCTD17,NEK11,RPS6KA2,SLC20A2,COA1,KDM4C,PSD3,PARD3,CDK20,RUNDC3B,ZKSCAN5,KCNK12,SSPN" Drug 6174_DN prochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NDRG2,ADD2,MRTFA,APOC1,CASK,KIF1A,BMP7,SOCS6,RAB28,OSBPL3,PPP1R16B,EDRF1,NR1D2,RASGRP2,PTK2B,FECH,FOXG1,ANKFY1,ZMYND11,ATXN2L,ITGA7,VWA5A,MAP4,NF1,SLC11A2,NUMA1,PDE4B,RC3H2,PRKCZ,RAB3A,TCP11L1,PAQR6,FOXRED2,ZNF821,AMBRA1,SLC11A1,SLC22A4,KDM4C,EXOC7,TCF4,TCF7,PSD3,TNS1,TSC2,UBTF,FLRT2,PLPPR2,ZNF225,NLRP3" Drug 2071_DN Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "AMT,APOC1,CDK10,CFLAR,ZFYVE9,WHRN,SLC4A7,CSNK1E,VCAN,FAM169A,SDC3,TOX,DBT,NR1D2,DMTF1,EDN1,SIDT2,RBM12,F3,SCARA3,INPP5K,SRCAP,ARFIP1,COPS8,GLRB,GPER1,SLC2A6,HNMT,SLC11A2,OGG1,MED1,TMEM260,HSPA4L,CCDC88A,COA1,KDM4C,ZBTB43,PBLD,CAMTA2,JMJD6,TCF7L2,UBTF,SF1,NT5M,NAV3,MPPE1,ST7,PHTF2,IFT88" Drug 2643_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "KIDINS220,NLGN4X,TRMT9B,APBA2,DGKD,PLA2G4C,NEURL1,TPP1,STOML1,FADS2,CREM,HAPLN1,LRIG1,CTH,CTNND2,DCAF4,NOS1AP,EDNRA,HSD17B14,ANKMY1,ARMCX1,FGFR3,RASL10A,AHDC1,GFER,GLYR1,GRIN1,KITLG,NDUFA5,NF1,PFKFB2,POLG,RGS10,RGS12,MYH14,TCP11L1,ZCCHC24,SPTAN1,IQSEC2,ZC4H2,AJAP1,ROBO3,WSCD1,PSD3,VIPR2,VSNL1,SPHK2,SLC30A3,FAM13C" Drug 1960_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ACLY,PKP4,GAS7,APLP1,CFLAR,CANX,SLC25A14,CBR1,FOXN3,CLTA,FADS2,AKAP12,NCOR1,CSNK1E,DPH1,ACSL4,FCGRT,FHL1,SEC23B,GAA,DENND2A,RNFT2,HNMT,L1CAM,MAP4,MBNL1,MBOAT7,QDPR,GAL3ST4,NUDT11,CLIP1,ATXN2,DOCK10,AMBRA1,RAB3GAP1,SMARCC2,CDK5RAP2,MAPKBP1,SON,TSPYL2,PHLDB1,WASHC4,NSD1,ARHGEF12,HEY1,TPM4,UBTF,SMIM8,LAS1L" Drug 3047_DN Nizatidine [76963-41-2]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ARID1A,AP1B1,PLA2G6,AMPD3,AMPH,ANK3,APBB2,AZGP1,ADGRB1,SGCE,CFAP410,MAP7,EPS15L1,RAB33A,CLCN4,CSNK1E,SIDT2,ELAVL3,EIF1,RASGRP2,LILRA2,PADI2,ATXN2L,KCNJ5,MDM4,SCAMP5,MYO7A,NNAT,PDE4D,PFKFB2,PHKG1,PROX1,TMEM231,ZNF821,SH3BGR,WDTC1,ARHGEF9,PLCB1,TAL1,TRIM2,PSD3,TMOD1,TPM1,TPM2,ZMYND8,ZFP37,SPHK2,KCNAB1,JPH3" Drug 2524_DN Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "PLA2G6,ARRB1,KIF1A,LDLRAD4,CFAP410,REPS2,CDH8,PICK1,CSF1,SIPA1L1,PDE4DIP,SPOCK3,CDON,RCAN1,EFNA3,SORBS3,LRRC23,RASGRP2,VPS26C,ADAM28,GNG3,LILRB4,GUCY1B1,SLC2A6,PADI2,ICA1,KCNMA1,MAP4,OXTR,ENPP2,PLCD1,LRRN3,RAB3IL1,SLC11A1,TSNAXIP1,DDN,LHPP,PLCB1,TAL1,TCF7,ATP13A2,SLC44A1,THRA,TPD52,SSBP2,XRCC4,ZNF32,SPHK2,SH3GLB2" Drug 6244_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "APP,ARNTL,ASPH,ADAM15,RGS11,CDH2,VAX2,DCAF8,DMPK,DSCAM,RCAN1,DTNA,SUGP2,EIF4G2,EPB41L1,STX2,ATP2C1,USP19,GLYR1,GLUL,CNTRL,PADI2,HMGCR,INPP5B,JAK2,LIG4,MPP2,ADAM22,ZNF862,NUMA1,PDE4A,RETREG1,LRP12,PPP5C,CNNM2,ELOVL2,SAFB,SEMA6D,RAB3GAP1,ARHGAP26,NSFL1C,ARC,EXOC7,WBP2,KLC2,XRCC4,MAP3K12,PHTF2,GAN" Drug 3078_UP Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADORA1,BEGAIN,ANK1,ANK3,APBA2,FUBP1,NEURL1,ARHGAP33,CHRNA4,NRXN2,SULT4A1,HOMER3,ABCG1,ARHGEF4,CTNND1,ARHGAP24,DCT,KLHL3,SMG7,DSCAM,USH1C,EDNRB,CELSR3,ELAVL3,CDHR1,HPCAL4,GNAO1,GPM6B,PCLO,MOBP,MPP2,GIT1,ADAM22,TAGLN3,NCAM1,TNPO2,PPP2R2B,CEP41,MAPK7,PTPRN2,RAD52,HKDC1,SLN,ASTN2,MTCL1,TNS1,VGF,NT5M,STMN4" Drug 6129_DN Piperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "CDC42BPA,PPFIA1,PKP4,ATM,SYNJ1,CAPN3,CDC42,ARHGAP33,PLAA,ENTPD4,DBT,RCAN1,HIPK3,FCF1,SUGP2,TNK2,ENO2,RASGRP2,WASF3,ADAM28,GLS,NCKAP1L,ICA1,MIA2,NEK1,NUMA1,OMG,GPR85,STRN3,MBOAT7,PEX5,RAD52,RAP1GAP,TCP11L1,MAP6D1,TRA2B,SLC11A1,SNCA,SS18,ATP11A,DNMBP,TCF7L2,TMPO,TNS1,ZKSCAN5,HIRA,XRCC4,SYNC,MARCH8" Drug 6310_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "AP2A2,MTUS1,CNTNAP1,APC,FAM131A,MARK4,ASPH,ATM,RIPK1,CCNT1,SEPT7,QKI,CNTNAP2,PPP6R2,TM9SF4,CNIH3,SPOCK3,DLG3,EIF5,ING4,ANKMY1,FCGRT,BACH2,ZNF862,NDP,RC3H2,CNNM2,ELOVL2,RAB5B,SH3TC2,RPS6KA2,SBF1,FAM102A,ASAP3,FUZ,SHANK2,WDTC1,ERC1,SYT11,KIAA0930,TMEM121,ZNF34,METTL3,TSC2,PLPPR2,TFIP11,MAP3K12,TIGD6,AAAS" Drug 2761_DN Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ABHD6,ARID1A,AK2,MRTFA,APBB2,PPFIA3,NCOA1,BCL7A,BMP7,MTMR3,ENTPD4,LRIG1,CTH,PPP6R2,MAML1,DSCAM,FEM1B,SIDT2,SORBS3,NCALD,F3,BAIAP2,DISC1,KIF5C,LSS,MBP,MITF,NPR2,SLC11A2,PDE3B,MED1,CNNM2,RNASEL,GSTCD,TCP11L1,SBF1,CCDC92,SLC1A7,SON,ZCCHC24,THSD1,ZNF34,TIAM1,TRIO,NSD2,FTSJ1,MPPE1,PHTF2,NUP214" Drug 2106_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "APC,MARCH3,BCL2L2,CFLAR,CANX,RCBTB2,NIPBL,HOMER3,SLC4A7,HINFP,CSNK1E,PPP6R2,TBC1D5,MATR3,HP1BP3,KIAA0753,KLHL3,SPOCK3,SIDT2,COQ7,ZNF589,BAIAP2,CAMSAP1,CSPG5,GLRB,HTATSF1,ACOT7,INPP5B,NFYA,SETD4,PLCD1,POLG,TMEM231,RPS6KA2,SBF1,ATXN1,ST6GAL1,SMTN,SMARCD3,SS18,KAZN,EXOC7,ZNF34,METTL3,SMUG1,TRIO,PRDM2,MPPE1,PHTF2" Drug 2290_DN Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADRA1D,APBA2,EPB41L5,APOC1,PLA2G4C,ALDH4A1,ATM,CA4,ARHGEF2,CACNA2D2,RCBTB2,CNOT8,AKAP7,GREB1,TBC1D5,DLG3,DUSP9,HSD17B14,ZNF589,KIAA1109,TPK1,TMEM8B,SPACA9,GRIK5,NR3C1,MAP4,MIA2,MYT1,NEK1,CNOT4,SERPINE2,PLTP,MAPK8,ELOVL2,PEX5,KCTD17,BTBD7,KIF13A,EMC1,ZBTB43,CLSTN2,PLCB1,ROBO3,FBXW11,CABIN1,WIPF1,LAT2,SLC30A3,WNK1" Drug 5008_DN Fluspirilen [1841-19-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ALAD,ASPH,CFLAR,CDK5R1,ARHGEF7,CACNA1D,SLIT2,LHX2,NMT2,ABCG1,MFAP3L,FBXL5,LYPD1,MAMLD1,RBM12,ENO2,SCML2,FGF12,BAIAP2,SEMA4D,GPR153,INPP5K,RAB30,MMP16,LYRM9,ZNF862,NRGN,RETREG1,LRP12,PPP2R2B,GON4L,CEP97,PAQR6,SH3BP2,FBXO11,SLC1A7,SMTN,FAM214B,SLC20A2,SLN,PDZRN3,VPS13A,EXOC7,ZNF34,VGF,EMSY,GDPD5,MPPE1,SMIM8" Drug 3091_UP Megestrol acetate [595-33-5]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ABAT,ABR,ABHD6,ADORA3,BIN1,ANK2,ANK3,APBA2,DNAH17,CHN2,TAOK2,ABI3BP,C2CD2,SPOCK3,SV2A,DLG4,RASGRP2,MTSS1L,ATP8A1,FGFR1,GABRA1,ZNF44,MGAT3,AFDN,MYO6,SLC11A2,NTRK3,NLE1,RELN,BCAS3,TMEM104,WDR25,ZSCAN32,PTPRN2,FAM120C,PID1,RAD52,RGS12,PLPPR3,NLGN1,SLC1A3,SLC11A1,UNC5B,ZC3H13,OBSL1,UBE3A,CLIP2,SH3GLB2,KCNAB1" Drug 3755_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "MTUS1,ADAM15,BTRC,CHM,TAOK2,CLCN4,LY86,PICK1,ENTPD4,CRMP1,PHF14,RIMS3,SMG7,CHRDL1,EGFR,ETV1,ANKFY1,PDLIM5,PNMA2,GFER,HTATSF1,MAP4K5,TM6SF1,NEK1,NFIX,CNOT4,PPARA,MED1,PRKAB2,PRKAR1B,ZSCAN32,ACSS3,SUPT20H,ASAP3,NLGN1,DZIP1,SNCA,ZHX3,CDK19,ARC,SYN2,SYT1,TBCEL,IQCE,ZEB1,TRIM2,TNS1,RUNDC3B,VLDLR" Drug 2199_DN Myosmine [532-12-7]; Down 200; 27.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NDRG2,AP1B1,APAF1,ARRB1,BACH1,SYNJ1,SLC25A14,INA,CD86,HOMER3,CSF1,PDE4DIP,DAPK3,RCAN1,EIF1,TUBD1,COQ7,RASGRP2,KIAA1109,GALC,GLS,POLL,ITGA7,KPNA5,LIG4,MAP4,ZNF862,NINJ2,NUCB1,PLP1,PILRA,RIPOR1,RAD52,RNASEL,SCG5,TMCC1,EMC1,CAND2,RAP1GAP2,NXT2,FBXW11,NSD1,TMPO,PARD3,RBFOX2,ZMYND8,ZNF32,PHTF2,SENP7" Drug 4272_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADRA1D,ANK1,APOC1,ATP1A3,SLC2A11,CACNA1I,CA8,CACNG1,KALRN,SCARB1,NCOR2,ATN1,ABCC9,SORBS3,MRNIP,ERBB4,GAB1,GAD2,GFRA1,PTGDR2,KCNB1,KCND3,KCNH1,KITLG,MMP17,CD200,MYT1,NPY,NUCB1,PDE4A,CAMKV,PTAFR,KLHL11,MYH14,EMID1,FRMPD1,CNKSR2,MAPK8IP3,SYP,ATP11A,DMXL2,SZT2,SLC19A3,PCDHA5,ICAM5,TRPC3,ZMYND8,CADM1,NUP214" Drug 2864_DN Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "MRTFA,AMT,APC,SEMA4G,SYNJ2,CA4,ARHGEF1,SCARB1,FAM189A2,HOMER3,AKAP7,DCAF4,DAPK3,HP1BP3,KBTBD11,SLC12A6,TSPAN5,CELSR3,MRNIP,FGFR1,IQCG,ANKFY1,NOP56,FAM49B,GPR153,ZNF44,HBS1L,SRCAP,CACFD1,INPP1,LIG4,MAP4,RETREG1,RETREG2,MBOAT7,PTHLH,RAD51D,RAD52,RGS10,SH3BP2,EPN2,THSD1,ATP11A,HEY2,TMOD1,ZMYND8,DNALI1,HPS4,ST7" Drug 6712_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "C1QTNF3,ANK2,APBB2,AQP4,PPP4R4,ARHGDIG,KSR1,FUBP1,CACNA1A,MTMR7,CACNA2D2,FAM149A,HAPLN1,FEZ1,DCT,MYEF2,C2CD2L,SRGAP3,MTSS1L,ST3GAL6,DBF4,GPR22,GRIK5,GRIN1,SOX21,KCNJ3,KCNJ5,VWA5A,ADAM11,ADAM22,PDGFRA,ENPP2,ABCB1,LRRN3,PPP5C,PTCH1,RASGRF1,ZNF821,RIMS1,ZNF423,ACSBG1,VAMP1,PCDHA5,SEZ6L,LILRA4,TPM1,SCG2,KCNAB1,JPH3" Drug 3034_DN Capsaicin [404-86-4]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "MTUS1,ALAD,APP,CFLAR,SYNJ1,MTMR2,B4GALT6,CLCN4,NMT2,IQCK,CSNK1E,RHOBTB1,FAM13A,SORBS3,COQ7,ZNF589,PDLIM5,CGREF1,GABRA2,INPP5K,WASF3,ATXN2L,ELOVL5,IL11RA,JAK2,SMAD1,NFYA,RETREG1,STRN3,MAPK7,RAD52,ZDHHC14,C12orf49,MCMBP,SCN2B,SH3BP2,RAB3GAP1,SLC20A2,RAP1GAP2,MAPK8IP3,PDLIM2,TCF7L2,TPM1,ZMYND8,SSBP2,ZKSCAN5,PRDM2,EVI5,UBE3B" Drug 4229_DN Cyclopenthiazide [742-20-1]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "RALGAPA1,MTUS1,TRMT9B,APP,SHROOM2,PDE8B,MAP7,SCARB1,REPS2,TPP1,DNAJB5,QKI,WHRN,PDE4DIP,ARHGAP24,DNAJC6,CNIH3,PLPPR4,EFNA3,ING4,PLEKHO1,COQ7,DENND4A,EFEMP1,ANKFY1,GLRB,IL11RA,DIPK1A,JAK2,LIG4,TAGLN3,CLDN11,PIK3R1,RETREG1,PLCD1,RC3H2,BCAS3,GON4L,PTCH1,PTPRN2,TMEM231,GSTCD,PPP1R9A,FNDC3A,TNIK,TROVE2,IQCE,ARHGEF12,ZNF34" Drug 2475_DN Benperidol [2062-84-2]; Down 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "DOC2A,BIN1,APC,SLC4A4,ADAM15,SYNJ2,CACNA1A,CCNT1,CHM,CNOT8,SLC4A7,AATK,DZIP3,ZFYVE16,DNM2,DTNA,LRRC23,NCALD,PIPOX,F5,PTK2B,DLC1,KAT8,ZMYND11,MUM1,KIF2A,MAP4,MDM4,NUMA1,OXTR,SERPINE2,PLCD1,SLC25A23,MAPK7,PTN,RAD52,FAM214B,SLC11A1,MYH15,DOK5,TROVE2,SUPT5H,TCF7,THBS4,ICAM5,KAT6B,GDPD5,PCBP4,NUP214" Drug 4653_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADCY6,CDK10,ARNTL,CDK13,ASPH,MTMR2,CANX,SPAG9,ARHGEF1,SCARB1,ZMYM4,TPP1,QKI,PDE4DIP,GIT2,DBT,EXOG,FCF1,EGFR,ETV1,ANKFY1,PDLIM5,ZMYND11,GART,ZNF276,GLRB,NR3C1,HSF2,TJAP1,DIPK1A,NDP,NFYA,PAK3,STRN3,FAM120C,FUZ,SHMT2,SLC22A4,ZKSCAN3,SS18,NXT2,TCF7L2,BHLHB9,SSBP2,HIRA,WIPF1,ZNF711,EVI5,PHTF2" Drug 6433_UP 5707885; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ACLY,ALCAM,APBB2,APP,LDLRAD4,CA4,CACNA1D,SOCS6,ZFYVE9,DNAJB5,QKI,PICK1,COL9A3,CHD1L,RIMS3,DAPK3,DTNA,EDNRA,EN2,ERCC2,CACNG3,ACSL4,FYN,GATM,ALDH1L1,NR3C1,GRM2,ACOT7,HSF2,ICA1,NEK1,LRP12,C1orf54,RPS6KA2,SYNDIG1,ASIC4,TAB2,CLSTN2,SS18,INKA2,CRTC1,DNAH7,TK2,VIPR2,VLDLR,NSD2,CLDND1,KCNAB1,RNF146" Drug 2946_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADRB2,APP,ASPH,ADAM23,ADAM15,CSF1,EDRF1,DGKG,CD320,ECSIT,KIAA1109,FGFR1,FLT1,PDLIM5,GABRA4,ZNF44,ZMYND11,INPP5K,SRCAP,GLYR1,MAP4K5,MAP4,NF1,ODF2,PIK3CD,NLE1,POLR2F,MAPK8,PTAFR,PEX5,ZNF493,GTDC1,RGS10,ZC3H14,DGLUCY,RASA3,TMCC1,WDTC1,KANK1,KAZN,DNMBP,KCTD2,R3HDM1,CABIN1,ZKSCAN5,PLPPR2,NT5M,PRDM10,PHTF2" Drug 6552_DN prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ANK3,PPFIA3,PDE8B,SLC4A4,SLC2A11,RGS9,CFLAR,FUBP1,SCARB1,ZFYVE9,SULT4A1,WHRN,SH2B1,NCOR2,TM9SF4,EXOG,SLC12A6,ATN1,EPB41L2,EZH1,ATF7,GPR19,INPP1,MAN2A2,MEF2C,NEK1,NF1,NRCAM,PLCD1,RAB3IL1,RGS4,SLC1A2,SLC15A2,LIMCH1,CLSTN2,STX1A,SYN2,FBXW11,WSCD1,CUX2,TCF7L2,TRIM2,AP4E1,TMOD1,ZKSCAN5,HIRA,VAV2,SLC30A3,CA10" Drug 4156_DN Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADORA1,KIDINS220,BIN1,CDC42BPA,SEMA7A,APC,DNAH17,MARK4,HAP1,NEURL1,CHM,PLEKHB1,FAM189A2,DNAJB5,CRMP1,CRY2,SNCAIP,RIMS2,ATN1,EFNB3,ING4,INPP5K,RND1,TJAP1,KIT,VWA5A,MDM4,ADAM22,NF1,PDE1C,PDPK1,RETREG1,PLCD1,RAB3A,RGS10,TCP11L1,RPS6KA2,SH3BP2,ASAP3,CPEB3,SNAP25,TROVE2,ROBO3,HEY2,TMOD1,TRPM2,VLDLR,PRDM2,KAT6A" Drug 2932_UP Zalcitabine [7481-89-2]; Up 200; 19uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "DOC2A,CDC14B,ARSE,AZGP1,LDLRAD4,CLCN4,HOMER3,CNR1,CREM,DGKG,SPOCK3,DLG4,SORBS3,DLC1,FGFR1,FLT1,KHDRBS3,GPR153,PCDH17,GNAS,SCIN,KCND1,KCND3,KCNMA1,MAP4,NCAM1,NINJ2,NPTX2,PFKFB2,MAPK7,PLPPR1,PTPRN2,TMEM255A,EMID1,HUNK,SEC14L1,ITSN1,BCAN,BTBD7,SNCA,ARHGAP26,LHPP,FCHO1,MAPK8IP3,VAMP1,MTCL1,ZFPM2,KCTD2,PLSCR4" Drug 449_UP radicicol; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ASIC1,MTUS1,AK2,APBB2,ARHGAP5,STX16,CLU,DNAJB5,CNTN1,HINFP,CSF1,SIPA1L1,SOCS5,CTH,ARHGAP32,GAPVD1,FBXL5,DNAJB6,E2F5,EGFR,TNK2,F5,PCYOX1,GAD2,ARFIP1,KTN1,LAMP2,MAOB,AFF1,CTNNA3,NAP1L2,OXTR,SERPINI1,MAPK3,ZSCAN32,PTPRN2,C1orf109,HSPA4L,DOCK10,LIMCH1,PDZD2,EMC1,ZC3H13,TSPYL2,EXOC7,TBL1X,BHLHB9,BEX4,JMJD1C" Drug 6081_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADD2,BEGAIN,SEMA7A,CDC14B,SEMA4G,ALDH7A1,NRP2,CFLAR,CACNG1,EPS15L1,KIAA1549L,DNAJB5,RGS6,NTM,HEYL,LRRC23,PIPOX,FOXF2,TPK1,GABRA2,GNAO1,PRUNE2,STON1,LPAR4,GRIA4,GRM7,SYNPO,ICA1,C2orf72,KCNB1,KIFC3,MYCN,CAMKV,MTRF1L,PURG,PPP5C,SAMD9,RGS10,EMID1,SH3BP2,ANKRD6,SLC2A5,KIF21B,KIAA1107,SLC19A3,R3HDM1,VLDLR,MVB12B,FAM13C" Drug 4784_DN Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "RBM10,ADCY6,DOC2A,EPB41L5,PPFIA3,ALDH4A1,RIPK1,CFLAR,CA12,SPAG9,SLIT2,HOMER3,AKAP7,SH2B1,LRIG1,HDAC4,GIT2,DCTN1,MED24,DLG3,DSCAM,DTNA,MRNIP,EPB41L2,AHDC1,CACFD1,IL6R,IL6ST,MITF,NUCB1,PLEC,MBOAT7,FSD1,PRKAR1B,NKAIN1,MYH14,ATXN2,ZNF821,SH3BP2,SCMH1,MAPKBP1,SPTAN1,NSFL1C,ASTN2,SEMA4A,TMEM121,UBTF,KLC2,SSPN" Drug 4972_UP Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NDRG2,AK2,APBA2,GAS7,ASPH,CDK5R1,HIP1R,SLC16A4,CLGN,SRSF11,HOMER3,SLC4A7,ARHGEF10,RASSF2,TBC1D5,MAML1,PARD6A,DTNA,EGR3,FGFR1,CAMSAP1,SRCAP,USP19,TXNL4A,GPM6B,GPER1,NXPH3,LSS,RETREG1,NLE1,PTHLH,ZNF493,RET,RGS12,SEC61A2,RPS6KA2,SGK1,FAM214B,SHANK2,SLC15A2,ZBTB43,PLCB1,ANKRD12,TBCEL,PARD3,CABIN1,WIPF1,LAT2,SEMA3B" Drug 1687_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ASPHD1,LTBP4,MRTFA,CDK10,ARRB1,ARRB2,NUMB,CFLAR,BMP7,QKI,HOMER3,CREM,CRY2,DBN1,DBT,DNM1,TRAPPC9,FER,FGFR3,DPYSL4,GPR153,CSPG5,SYT17,GART,NR3C1,FICD,RNFT2,INPP5B,KIF5C,LIG4,SLC11A2,ELOVL2,PTK2,RAB3A,RALGDS,RXRA,KIF16B,EPN2,SMTN,JMJD6,TACC1,EHBP1,TCF7L2,TRIM2,DOCK9,CDK20,HIRA,SMIM8,ACTR3B" Drug 4384_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "AP2A2,KIAA1324,ALK,BIN1,CNTNAP1,CDC14B,SEMA4G,BRINP2,CACNA1I,LDLRAD4,CAMK2G,CLCN4,ARHGEF6,WHRN,CSF1,RIMS3,DMPK,PIPOX,FGFR1,FGFR3,FOXG1,AGAP2,SEMA4D,DCTN2,RUNDC3A,GNG4,GRIK5,GRM1,KLF12,KIT,MID1,NPPA,NTRK2,PDE4B,SAMD9,PTX3,CCDC40,MAPKBP1,ZCCHC24,SAMSN1,VAMP1,SMG6,CRTC1,HEY2,UBE3A,VAV2,MICAL1,PRDM2,NUP214" Drug 4211_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ADRB2,CDC14B,BACH1,NRP2,CACNG1,CALB2,SCARB1,CLCN4,SULT4A1,IFFO1,PDE4DIP,DAPK3,SPOCK2,DYRK1A,SEMA3D,SIDT2,AGAP2,PDLIM5,PRELID3A,DENND2A,GAD2,GALC,GPR75,GNG3,AP4S1,HPSE2,ICA1,IGFBP1,MYH3,NF1,OPRL1,PHKG1,SERPINI1,CAMKV,PIK3CD,CNNM2,ZSCAN32,SH3TC2,EMID1,ST8SIA1,SLA,SLC11A1,SNCA,TROVE2,TBCEL,PCDHA5,ZKSCAN5,VSNL1,LAT2" Drug 5051_DN Roxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "APC,APLP1,LGR5,MARCH3,SLC4A4,EIF4G3,BCL2L2,SOCS6,CHM,AKAP7,IQCK,SLC4A7,NRG2,CSF1R,VCAN,SLITRK5,SPATA2,RCAN1,FAM13A,EGFR,ZNF589,SCARA3,FYN,ZMYND11,INPP5K,COPS8,GPER1,JAK2,NPR2,ODF2,MAPK7,CNNM2,ZDHHC14,FBXO11,DZIP1,FAM214B,ZNF667,TROVE2,EPB41L3,SS18,NXT2,CEP68,JMJD6,AHCYL2,GPR161,TK2,TRIO,OSBP2,SPHK2" Drug 1732_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NDRG2,ADCY2,ADD3,AMT,CNTNAP1,ARNTL,SLC4A4,CADM3,SEC31B,FEZ1,PPP1R16B,DOCK4,EPS8,CDKL3,CEND1,ZMYND10,FGFR1,PCYOX1,INPP5K,GJB1,NXPH3,KIF5C,NCAM1,NUCB2,SERPINI1,CCSER2,RETREG1,PLCD1,LRP12,PRRX1,PTX3,SATB1,SBF1,SLC15A2,DOP1A,ZCCHC24,NXT2,RGL1,STXBP1,NSFL1C,VPS13A,CAMSAP2,TCF4,SZT2,R3HDM1,TNS1,NPDC1,MARCH8,SMIM8" Drug 6514_DN Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ASPHD1,ABHD6,DOC2A,BIN1,APC,APLP1,ALDH4A1,MTMR9,MPDZ,SYNJ2,CDH8,MAGI1,CACNA2D2,CLU,CREM,DAPK3,MFAP3L,SIDT2,ING4,F8,DISC1,TXNL4A,GNG4,STON1,GPR37,CNTRL,ITPKB,VWA5A,NF1,NFYA,PDE3B,FAM120C,NKAIN1,ARID4A,SAFB,ZNF821,SYBU,PEX26,EPN2,THSD1,NXT2,FAM168A,ASTN2,RPGRIP1L,TPM1,HIRA,FAM155A,PLPPR2,CLDND1" Drug 2956_DN Torsemide [56211-40-6]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "GRAMD1B,CDC42BPA,APBB2,ASPH,RIPK1,RCBTB2,EPS15L1,RAB28,ENTPD4,CST3,SLITRK5,DOCK4,DTNA,EIF5,ING4,COQ7,EZH1,FHL1,FLT1,ERAP1,GLYR1,GOLGB1,PRRC2B,GSN,ICA1,IL11RA,ITGA7,MX1,STRN3,MINDY2,PTPA,PPP3CC,PTPRO,RAP1GAP,SH3BP2,FAM214B,SLC15A2,ARFGAP1,SPATA7,ZCCHC24,DMXL2,TCF7L2,KAT6B,TNS1,HSPBP1,SPHK2,WNK1,PRDM2,UBE3B" Drug 5967_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ALK,AMH,APAF1,FAM131A,APOC1,PLA2G4C,ALDH4A1,CFAP410,CBFA2T2,SCARB1,FOXN3,FADS2,NECTIN3,CRMP1,DBN1,CNIH3,EFNA3,EGFR,ERCC2,F5,CAMSAP1,SCARA3,FOXG1,GALC,GFER,USP19,GLS,TDRKH,GPR19,GPER1,CNTRL,KCNH2,MYCN,PCDH9,WDR25,ELOVL2,SLC4A3,SLC1A7,PPP4R3A,SNCA,KDM4B,TACC1,CHST8,TMOD1,ZBTB14,NDRG4,TFIP11,SLC30A3,KAT6A" Drug 1731_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ASIC1,NDRG2,AMT,CDC42BPA,CAMK2G,KYAT1,AP4M1,TAOK2,SLIT2,CLCN3,CNTFR,AKAP7,SPOCK2,DLG3,DTNA,EFNB3,EPHB1,ECSIT,OLFM1,CAMSAP1,INPP5K,ALDH1L1,USP19,PRRC2B,NXPH3,ITGA7,KIF5A,MGAT3,NF1,NFYA,NTRK3,ODF2,MAPK3,PTPRN2,ATXN2,SH3BP2,CCDC88A,KBTBD4,MAPKBP1,WDTC1,DBNDD2,NCDN,PLCB1,WWC1,SZT2,DAAM2,PARD3,RBFOX2,MARCH8" Drug 6156_DN "(+,-)-Synephrine [94-07-5]; Down 200; 24uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ARID1A,MRTFA,ARRB1,CDK13,MARK4,N4BP2L1,CA12,CAPN3,ZFYVE9,PLAA,CLCN4,CSNK1E,CTNND1,EDRF1,CTIF,C2CD2L,NR1D2,ST3GAL6,EFCAB2,GABRA4,SEPT9,ZNF276,HTATSF1,POLL,SPACA9,ITIH2,LSS,MID1,N6AMT1,LYRM9,ZNF862,OMG,PRKCZ,RAD52,ZCWPW1,RET,FAM102A,STX1A,KIAA1107,TCF7L2,SYNE1,TEX15,TMOD1,PARD3,TNS1,TPM2,ZMYND8,PLPPR2,TRIM9" Drug 3452_UP Methacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "C1QTNF3,APBB2,GAS7,ARHGDIG,ATP6V0A1,CFLAR,BTRC,AKAP7,WHRN,ENTPD4,ATRNL1,GREB1,RIPOR2,SPOCK2,GNE,EML1,VPS13B,NCALD,FGFR1,BAIAP2,FHL1,SRCAP,GPR19,KCNH2,MEF2C,ZNF862,PDE2A,PLXNB1,PACSIN1,MINDY2,ZSCAN2,RAD52,RPS6KA2,PEX26,SMTN,SLC22A4,FAIM2,WDTC1,ZBTB43,NPAS3,COBL,SYT5,TRIM2,PSD3,CRTC1,ZMYND8,PDIA2,EVI5,SSPN" Drug 3163_DN Glibenclamide [10238-21-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "ABHD6,PPFIA3,CAPRIN2,BCL7A,CAMK2G,SOCS6,FAM189A2,HOMER3,AKAP7,CRY2,CTNND2,RABGAP1L,TOM1,CNNM1,SORBS3,EIF5,VPS26C,ANKFY1,FYN,SYT17,MALT1,POLL,FERMT2,TDRKH,GRB10,HSD17B1,INPP5B,MATK,MDM4,MIA2,NF1,CNOT4,RGS3,RGS10,RPS6KA2,SBF1,SGK1,EPN2,BTBD7,EXOC7,TCF7L2,CRTC1,PCDHA6,TMEM121,ZNF34,HIRA,LMF1,REEP1,MPPE1" Drug 7539_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "NME5,AMPD3,ANK3,EPB41L5,SLC4A4,CFLAR,CACNA1I,BAIAP3,CBFA2T2,AP4M1,VCAN,DGKB,EXOG,TNK2,LRRC17,STX2,ZNF391,KIAA1109,FLT1,C1QL1,GPD2,KCNMA1,KIF5C,L1CAM,NF1,NOVA2,SETD4,POLG,CEP41,CNTLN,PEX5,TMEM231,RGS4,GSTCD,SUPT20H,SLC9A5,SHANK2,ZNF667,TSNAXIP1,IQSEC2,COBL,TBL1X,UGT8,LMF1,ZBTB14,ZNF74,TFIP11,WNK1,SEMA3B" Drug 325_UP radicicol; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "AGT,SYT13,PPFIA1,APP,ATP2B1,MPDZ,BCL7A,KRIT1,CRMP1,ARHGEF10,ATN1,RCAN1,SIDT2,SUGP2,BAIAP2,SMC2,PDLIM5,B4GALNT1,HPS5,AGBL5,HSF2,ICA1,KTN1,L1CAM,ADAM22,PTOV1,NAP1L2,NEK1,NNAT,CDK18,SMIM7,MBOAT7,PACSIN1,PRODH,RGS3,HSPA4L,ITSN1,SMARCE1,KDM4B,VPS13A,ANKRD28,CLASP1,TNS1,TRIO,UBE3A,PLPPR2,ZIC1,ZNF189,MAP3K12" Drug 4470_DN Cyproterone acetate [427-51-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "RALGAPA1,AP2A2,APBB1,APBB2,CFLAR,SCAPER,BTRC,CLCN4,AKAP7,SLC4A8,AATK,AK5,DMPK,ING4,ETV1,EZH1,FGFR1,CINP,FYB1,INPP5K,SYNPO,MAPT,GIT1,MX1,ODF2,ZNF426,GON4L,SNRK,PID1,RGS7,SLC25A36,TMEM156,ASAP3,BTBD7,SLC20A2,ZNF667,COA1,TMCC1,EMC1,SYT1,KAZN,TK2,BEX4,HIRA,CADM1,ZNF24,UPF3A,WNK1,URM1" Drug 338_UP "azathioprine, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 4.42E-04 1.00E+00 3.59E-03 4.09E-02 49 195 "BRAP,BIN1,ANK1,KCNAB2,CDK10,ARNTL,PLA2G4C,ATP6V0A1,SDC3,DYRK1A,EDN1,SIDT2,EFNB3,ING4,ENO2,EPHB1,STX2,SEMA4D,TRMO,CAMKK2,PRELID3A,FYB1,ERAP1,GNAL,GSN,ATXN2L,ITPKB,KIFC3,L1CAM,PTOV1,NF1,PCBP3,SLC11A2,NRGN,GPR173,EPN1,PPP2R2B,ZCWPW1,EMID1,FOXRED2,SH3BGR,ELMO2,CAND2,KAZN,TBL1X,PLPPR2,WIPF1,MVB12B,AAAS" Drug CID005311456 MTPG Stitch 4.54E-04 1.00E+00 3.69E-03 4.20E-02 8 14 "CACNA2D1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,MAP4" Drug CID000073026 HOOBt Stitch 4.54E-04 1.00E+00 3.69E-03 4.20E-02 8 14 "BOC,CHRDL1,GGT7,GGT5,OGDH,PTN,TMEM132D,TK2" Drug CID000004177 Me-lex Stitch 4.54E-04 1.00E+00 3.69E-03 4.20E-02 8 14 "TOX,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HMGCR" Drug CID000000861 D-triiodothyronine Stitch 4.60E-04 1.00E+00 3.73E-03 4.24E-02 90 409 "ACHE,ADRB2,AGT,C1QTNF3,MYH7B,APOC1,APOC2,APP,NCOA1,STX16,ATP2A2,ATP2B1,ATP2B2,ATP2B3,SLC2A11,FGF17,USP6,CD38,SULT4A1,SH2B1,NCOR1,NCOR2,CRYM,CS,MED12,FGF1,FGF11,FGF12,FGF13,FGF14,ACTL6B,ATP2C1,GCK,GGT7,GGT5,GHR,PPARGC1A,BRD8,GPD1,GPD2,NR3C1,GSTM5,GSTT2,IGF1,IGFBP1,KCND2,MBP,MSRA,MT3,DDX25,MYH3,MYH6,MYH7,MYO5A,MYO6,SLCO1C1,NRGN,PCSK1,PCSK2,PFKFB2,PFKFB3,PFKFB4,PFKP,PKM,TRHDE,PPARA,MED1,PRKCB,PRKCG,PKN2,PRKCZ,MYH14,GSTCD,RORB,RXRA,RXRG,MYO18A,SLC2A5,TMEM132D,USP33,SST,APOM,ADHFE1,TAC1,TAC3,TF,AKTIP,THRA,ACTR6,TRH" Drug CID000000730 guanosine 5'-diphosphate disodium salt Stitch 4.63E-04 1.00E+00 3.76E-03 4.27E-02 134 650 "ABR,ADCY5,ADCY6,ADCY8,BRAP,ADRA1B,ADRB2,KIDINS220,AP2A1,AP2A2,AP1B1,NME5,ARHGAP20,ARHGDIA,ARRB1,SEC11C,AP1M1,CACNA2D1,KRIT1,CCNH,ARHGEF1,ENTPD6,CDC42,COPB2,CHM,CHN1,CHN2,CHRM1,ARHGAP22,CLTA,CLTC,NGEF,SULT4A1,AKAP5,ENTPD4,SEC24C,GPSM1,ARHGAP32,ARHGAP24,MAGI2,RHOBTB1,DMD,DNM1,DNM2,DRD1,ACOT8,DNM1L,EEF1A2,EEF1D,KLHL5,FAM13A,EGFR,RASA4,EIF4G1,EIF5,BSCL2,TUBD1,RASGRP2,ERCC2,PTK2B,TUBB3,TUBB4A,SEC24B,AGAP2,RASL10A,FUT9,GCK,TUBA8,RAB40B,GNAL,GNAO1,GNAS,GNG3,GNG4,TUBA1C,RAPGEF4,RAPGEF1,LINGO1,ARHGAP36,TUBB2B,ARHGAP12,MAG,KITLG,MT3,NF1,NME4,OCRL,OMG,PDYN,GNG2,PKM,GPSM2,SEPT4,POLR2F,PRKCB,PRKCG,PTK2,RAB3A,RASGRF1,RGS10,RIT2,RNASE1,RPL15,RPL38,RPS20,RTN1,MRAS,COPZ1,RPH3A,SLIT1,ARFGAP1,ARHGAP26,FGD4,SUPT5H,ARHGEF9,PLCB1,MLST8,MCF2L,ALG1,TBL1X,ZEB1,TIAM1,TRIO,TSC1,TSC2,TUBB2A,TUBB1,PITPNB,VAV1,VAV2,XPO1,TUBA1A,RTN4,NUP214" Drug CID000005244 dehydroepiandrosterone sulfate Stitch 4.65E-04 1.00E+00 3.77E-03 4.29E-02 65 277 "ADORA1,ADORA2A,ADORA3,NR0B1,APOC2,ARNTL,CCK,P2RX6,CDO1,CHGA,SLC22A6,NRXN2,ABCG2,CNTFR,CRHBP,SH2B1,CX3CR1,BOC,DBI,RBM12,LPAR6,ACSL4,EFEMP1,SEMA4D,KHDRBS3,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,ACSS1,GK,LPAR4,GRIN2C,GRIN2D,NR3C1,TNFAIP8L3,IGF1,IGFBP1,MYO6,P2RY13,NDUFA5,P2RX7,P2RY1,PDE3B,SLC10A4,PPARA,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,SLCO1A2,ACSBG1,ACSL6,TPD52L2,TRH,P2RY12,NETO1" Drug CID006480473 AC1O59H4 Stitch 4.68E-04 1.00E+00 3.80E-03 4.32E-02 19 55 "ADAR,ADARB2,ASCL1,MYEF2,DYRK1A,EPB41,AHCYL1,ALDH1L1,HNMT,HNRNPK,MAT2A,MEF2C,MTR,NEUROD1,PCMT1,FBXO11,SNRPN,EPB41L3,AHCYL2" Drug CID000003440 furosemide Stitch 4.74E-04 1.00E+00 3.84E-03 4.37E-02 64 272 "ADCY2,ADCY5,ADCY6,ADCY8,ADD1,SLC12A5,AGT,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,C5,CA4,CA8,CA12,CACNA2D1,CCK,SLC5A11,SLC22A6,CLCN3,CLCN4,CLU,SLC4A7,SLC4A8,HAPLN1,CYBB,DCT,SLC12A6,NRN1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GNAS,KCNK3,KITLG,MTR,NBL1,NPPA,KLK6,PTPRN2,SLC1A2,SLC1A3,SLC6A1,SLC6A11,SLC12A2,SLC12A4,SLC15A2,SLC20A2,SLCO1A2,SPP1,TSPYL2,TAC1,TAC3,TNFRSF1B,RBFOX2,RGMB,CA14" Drug CID000003518 guanethidine Stitch 4.75E-04 1.00E+00 3.85E-03 4.38E-02 32 113 "ACHE,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,ANK2,BCHE,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CCK,CHRM1,CHRNA4,CHRNB2,DMPK,B3GAT1,CRCP,KCNH2,BCO1,NOS1,NPY,OPRL1,P2RY1,SCN4B,SST,TAC1,TAC3,TACR1" Drug CID000005691 wartmannin Stitch 4.75E-04 1.00E+00 3.85E-03 4.38E-02 163 813 "ADORA3,AGT,MYH7B,DGKZ,CDK13,ATM,SLC2A11,ALDH7A1,CFLAR,BTK,CALM1,CAST,CCK,RGN,AIFM1,SCARB1,LRBA,CDC42,CHRM1,ZFYVE9,CLCN3,MYL6B,CLTC,CSF1,ZFYVE16,LYPD1,DOCK2,TOM1,EDN1,EDNRA,SGK2,EGFR,PLEKHO1,STX2,ERBB2,ERBB4,TMEM74,CD320,RPS6KC1,PTK2B,FCGR3A,FGF1,ACTL6B,UBE2E3,FOXO3,FLT1,CAMKK2,FYN,GAB1,MSTN,GHR,LYVE1,GPR75,GNAO1,GOLGB1,ADAP1,GRB10,RAPGEF1,ZHX1,DDX19B,TNFAIP8L3,HMX1,HSP90AA1,HTR5A,MYLK2,IGF1,IL6ST,IL12A,ITGAM,JAK1,JAK2,KCNMA1,KCNQ2,KIT,LIG4,MATK,MEF2C,KITLG,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NFE2L2,NODAL,NOS1,NPY,NRGN,NTRK2,OLR1,OXTR,P2RY1,KCNK10,PCSK5,PDE3B,PDGFRA,ENPP2,PDPK1,PFKFB2,PFKFB3,PFKFB4,CDK14,ABCB1,SSH1,PIK3C2A,PIK3CD,PIK3R1,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,PTK2,RAB5B,RAD17,RAD52,RET,MYH14,GSTCD,RPS6KA2,RTKN,MAPK12,SGK1,MYO18A,FNDC3A,SLA,SLC2A5,SLC9A5,CDK5RAP2,STAU1,STX1A,FGD4,SYT1,EXOC7,TEK,TF,LEFTY2,TIAM1,ACTR6,PIK3R5,TP53BP1,TRPC1,TSC1,TSC2,VAV1,VAV2,P2RY12,RICTOR,XRCC4,SLC38A1,PLD4,ST8SIA2" Drug CID000643668 discodermolide Stitch 4.76E-04 1.00E+00 3.86E-03 4.40E-02 14 35 "NCOA1,NCOR1,NCOR2,TUBD1,TUBB3,TUBB4A,TUBA8,GPR162,TUBA1C,TUBB2B,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID000079091 "1-chloro-1,2,2-trifluorocyclobutane" Stitch 4.83E-04 1.00E+00 3.92E-03 4.46E-02 11 24 "CHRM1,GLRB,GRM1,GRM5,HTR2A,KCNH2,KCNJ3,KCNQ2,PRKCG,SCN2A,TPM3" Drug CID000498506 dihydroxy(oxo)azanium Stitch 4.83E-04 1.00E+00 3.92E-03 4.46E-02 11 24 "DDR1,CLDN10,WAC,GPT2,NBL1,OPA1,PENK,SMOX,PPP1R1A,TJP1,TK2" Drug CID000107704 beta-CCM Stitch 4.83E-04 1.00E+00 3.92E-03 4.46E-02 11 24 "ABAT,CBR1,DBI,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,ZEB1,RTN4" Drug CID000008932 digitoxigenine Stitch 4.87E-04 1.00E+00 3.95E-03 4.49E-02 18 51 "CA4,PCYT1B,FCGRT,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCNC1,KCNC2,HCN1,ENPP2,SARS,PDZD2,SPX,UBE3A,ZIC3,RNF103" Drug CID000137994 tempol Stitch 4.89E-04 1.00E+00 3.96E-03 4.50E-02 54 221 "AP1B1,AGT,APAF1,NUMB,CALB2,AIFM1,CD38,VCAN,CYBB,DLG4,DRD1,EDN1,ATL1,ELN,GPHN,KAT8,KCNMB4,GRK4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,KAT7,IGFBP1,KCNMA1,NCF2,NF1,NOS1,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,RBBP8,RTKN,S100B,MAPK12,MYO18A,SLC1A3,ERC1,SYP,TBL1X,SIRT1,XRCC4,ZBTB16" Drug CID000001032 propionate Stitch 4.91E-04 1.00E+00 3.98E-03 4.53E-02 62 262 "ACHE,ABHD6,ALAD,BBOX1,AMT,RIPK1,CACNA2D1,HAP1,NGB,CBS,SLC4A8,CS,HDAC9,HDAC4,DLG4,EIF4G2,GPHN,CACNG2,DCTN2,ACSS1,DNER,GFAP,LPAR4,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,HBA1,TNFAIP8L3,IGF1,KCNH1,MAT2A,MTR,NEFM,PAH,PC,GNG2,PENK,NLE1,ACSS3,SLC1A2,TMEM132D,HECW1,AKNA,CYB561A3,PCBP4,NELFE" Drug CID000003025 dibucaine Stitch 4.95E-04 1.00E+00 3.98E-03 4.53E-02 22 68 "ASIC1,ACHE,BCHE,CACNA1B,CALM1,RGN,ASIC3,CP,CALN1,SLC25A18,DTNB,PHC2,NFYA,OGDH,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TF,PLPPR5" Drug CID005288987 DB02841 Stitch 4.95E-04 1.00E+00 3.98E-03 4.53E-02 22 68 "ADORA2A,KIDINS220,ABCD2,GPAM,CANX,ABCG2,ABCG1,DTNB,EBF1,F8,TUBB4A,MCHR1,RAPGEF4,MBNL1,ABCB1,PLIN1,PLXNB3,STX1A,ACSBG1,ABCC8,SYN2,PMEPA1" Drug 2666_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.96E-04 1.00E+00 3.98E-03 4.53E-02 45 176 "CLK4,MTUS1,PLA2G6,AMPD3,APAF1,DNAH17,CDO1,CREM,CRY2,PDE4DIP,KIAA0513,ZNF337,DGKG,HIPK3,FAM13A,MBNL2,EIF5,BAIAP2,PRKAG2,FOXG1,CAP2,OGA,GCNT2,LILRA2,STON1,MOBP,NINJ2,KCNK10,PDE4B,PLCD1,PMP22,MBOAT7,PRKACB,HSPA4L,SLC15A2,TMCC1,SPTAN1,DNMBP,RPGRIP1L,AHCYL2,KCTD2,TPM1,ZBTB38,UBE3B,FXR1" Drug CID003331970 "4-aminopyrrolidine-2,4-dicarboxylate" Stitch 4.97E-04 1.00E+00 3.98E-03 4.53E-02 15 39 "ADORA1,ADORA2A,ADORA3,CACNA1B,CACNA1E,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PENK,TSC2,SLC17A6" Drug CID000002498 C16-ceramide Stitch 4.97E-04 1.00E+00 3.98E-03 4.53E-02 15 39 "C5,CCKBR,CERS5,CD38,DSCAM,FOLH1,GNAS,IFI16,MX1,ENPP2,RAD17,TIE1,PORCN,ANKS1B,HPS4" Drug CID009959010 CID9959010 Stitch 4.97E-04 1.00E+00 3.98E-03 4.53E-02 15 39 "CD38,CHRM1,INPP5K,LSS,PCDHGC3,RYR1,RYR3,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,TRPM2,TST" Drug 5578_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.99E-04 1.00E+00 3.98E-03 4.53E-02 46 181 "AGT,OSBPL1A,MRTFA,BIN1,SEMA4G,PPP4R4,ADAM23,USP2,CLGN,JAM2,TPP1,DNAJB5,CTH,EDRF1,MBNL2,ING4,SORBS1,SRCAP,GPR37,DIDO1,NR3C1,ICA1,IL6R,MDFI,NAP1L2,PDE1C,EPN1,POU3F4,HSPA4L,SGK1,SH3BGR,PPM1E,CPEB3,SORCS3,TNIK,ZCCHC24,JMJD6,POPDC3,TAC3,DMXL2,ZEB1,TRIM2,UCHL1,SPHK2,FXR1,DPF3" Drug CID000064735 LaCl3 Stitch 5.00E-04 1.00E+00 3.98E-03 4.53E-02 17 47 "ADRB2,AMT,ATP2B1,ATP2B2,CACNA2D1,CALM1,CCK,KRIT1,RGN,AIFM1,PTK2B,MAP4K5,GSTCD,MLC1,ABCC8,TRPC1,P2RY12" Drug CID004534086 KB-R7943 Stitch 5.00E-04 1.00E+00 3.98E-03 4.53E-02 17 47 "ASIC1,SLC24A4,ATP2B1,ATP2B2,SLC24A2,RCAN1,GRIK1,GRIK4,GRIK5,GRM1,RYR1,RYR3,SLC8A2,SLC12A2,PEG10,SYNE1,TRPC1" Drug CID000000138 delta-aminovaleric acid Stitch 5.00E-04 1.00E+00 3.98E-03 4.53E-02 17 47 "ABAT,ADORA1,TAOK2,BOC,F5,GABBR1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,AHCYL1,GATM,KCNK3,TPM2,PCDH15" Drug ctd:C063302 KN 62 CTD 5.00E-04 1.00E+00 3.98E-03 4.53E-02 17 47 "CAMK2A,CAMK2G,NCOR2,EDN1,EDN3,EDNRB,GAP43,PPARGC1A,ITGAM,MEF2C,NOS1,NPPA,P2RX7,ENPP2,MAPK3,SYN1,NLRP3" Drug 5597_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 47 186 "DPF1,LDLRAD4,CFAP410,CA4,CACNG1,ARHGEF2,LY86,NRG2,SNCAIP,CSF1R,PDE4DIP,CTH,FRY,ING4,GFAP,RND1,HPCA,MAOB,MAP2,NELL2,NNAT,OMG,PCSK2,GPR85,CDK14,MTRF1L,LRP12,GDPD2,C1orf54,RASGRF1,RFX2,CNKSR2,SLC1A7,CXXC4,SNCA,KDM4B,SYT11,TCF7,TRIM2,PCDHGB6,PCDHGA10,CRTC1,HEY2,UGT8,WIPF1,KCNAB1,FAM13C" Drug 841_UP resveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 47 186 "ADRA1D,RGS20,SLC2A11,N4BP2L1,TMEM257,CRY2,PDE4DIP,CTH,GIT2,CELSR3,MBNL2,EGR3,LRRC23,ARMCX1,ST3GAL6,KIAA1109,FYB1,GAB1,SESN1,GNAS,GPR19,NR3C1,GRM8,IRAK3,AFDN,SAMD9,TMEM104,C1orf54,CARF,TCP11L1,PAQR6,SCN2B,SH3BGR,ITSN1,FRMPD1,FNDC3A,SYBU,ZKSCAN3,SNCA,TSPYL2,THSD1,SYT5,POPDC3,ROBO3,VIPR2,SF1,NAV2" Drug 4130_DN Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,AMH,AMPH,APC,ARHGDIG,PDE8B,ATM,KIF1A,CFAP410,CA4,RUNX1T1,STOML1,NRG2,CPS1,ARHGEF10,RUSC2,HS3ST2,DSCAM,DUSP9,EDNRA,ING4,ZNF589,FGFR1,CAMSAP1,FHL1,C1orf61,GAD1,USP19,RAB30,GLS,GRIK5,HLF,TJAP1,MYO7A,NEUROD1,LRP12,FAM120C,TCP11L1,ZNF821,BCAN,IQSEC2,VAMP1,PLCB1,POPDC3,SMG6,PCDHGB6,TNS2,HEY2,SCG2" Drug 6313_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADORA1,ALAD,MRTFA,TRMT9B,CADM3,KIF1A,SYNJ2,CACNA1G,LDLRAD4,NDST3,LHX2,RIMS2,CTIF,ATN1,EFNA3,PLXNC1,EIF4G2,MRNIP,LRRC17,FGFR1,USP19,ZNF276,GLI2,CNTRL,SCIN,INPP5B,KCNF1,KHK,NF1,PDE4A,PFKFB2,CAMKV,SNRK,PTCH1,ACSS3,RAD52,RGS10,MRAS,FRMPD1,TNIK,SSTR2,TACR1,TAL1,KLHL4,NSD1,PCDHA5,LAT2,ZIC3,KCNAB1" Drug 412_DN tetraethylenepentamine pentahydrochloride; Down 200; 100uM; HL60; HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,MRTFA,DOC2A,ANK2,EPB41L5,SEMA4G,PDXK,PDE8B,SLC4A4,LDLRAD4,P2RX6,CBFA2T2,LARGE1,CHRNB2,CNTN1,RIMS2,ECE2,EDNRA,CNNM1,ABI2,SORBS3,ELAVL4,OLFM1,SEC23B,TMEM8B,ALDH1L1,PCDH17,GNG3,TDRKH,PADI2,ITIH2,LAMP2,NF1,NTRK2,OMG,PAK3,CAMKV,PLCB2,PACSIN1,PPM1B,MASP1,SH3BP2,SH3GL3,SNAP25,VAMP1,CA14,LAT2,ZNF74,NUP214" Drug 4342_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ALK,BEGAIN,APOC1,CDC14B,CDK13,ZSCAN18,DDX3Y,CFAP410,SCARB1,SYNGR3,ARMC8,CP,SNCAIP,ARHGEF10,CNTNAP2,CYBB,DNAJC6,RABGAP1L,DTNA,ELN,PRELID3A,GRM1,RASSF8,IL6R,MAP4,TM6SF1,MT1M,NOS1,NUMA1,SNTG1,PALM,CCDC40,RGS10,TCP11L1,CXXC4,TNIK,SP4,IQSEC2,DDN,LMO3,EXOC7,DMXL2,ZFPM2,THRA,TPM3,ZIC3,NT5M,NAV2,MVB12B" Drug 3383_DN Hymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASIC1,LTBP4,MRTFA,SEMA7A,APBA2,FAM131A,SLC2A11,CA12,CACNA1D,HAP1,USP2,ASIC3,ZFYVE9,SIPA1L1,PHF14,ARMCX2,ATN1,DLC1,FGFR1,PDLIM5,GPR153,DHX35,ICA1,IL6R,IL6ST,INPP5B,VWA5A,LYRM9,CDK18,PLTP,LRP12,POLG,PRKAR1B,PTPRO,FAM184A,KCTD17,AMBRA1,PKNOX2,KDM4B,CAMTA2,THSD1,SMG6,DMXL2,CRTC1,PCDHA6,TMOD1,ZMYND8,ZNF24,WIPF2" Drug 5642_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADRA1D,C1QTNF3,CNTNAP1,APBA2,GAS7,DGKD,CDC14B,N4BP2L1,NRP2,CA4,KYAT1,CHN2,WHRN,CRMP1,SDC3,GREB1,DTNA,ABCC9,EDN3,TNK2,RCAN2,CAMSAP1,PDLIM5,GPR153,GRIA4,KCND3,KIF5A,MAN2A2,MAOB,OPCML,PALM,PDE4A,PLCD1,MAPK10,ROM1,SH3BP2,SLC1A3,KANSL3,PKNOX2,CXXC4,SNCA,TSNAXIP1,ATP10B,POPDC3,SLC44A1,TK2,VLDLR,PRDM10,KCNAB1" Drug 5251_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "APBA2,CDK13,BRINP2,CACNA1G,CFAP410,RUNX1T1,CHI3L2,CLCN4,AKAP5,CRY2,SPOCK2,RASGRP2,F5,REEP2,CACNG3,KIAA1109,FHL1,HPCAL4,FOXG1,FUT9,NEU3,KLF12,HTR2A,C2orf72,KCNH2,KCNJ4,KIT,MYO7A,NF1,PCSK5,PDE1C,ZSCAN32,SLC1A7,PKNOX2,SLC8A1,BTBD7,HECW1,CDK19,EXOC7,TCF4,DMXL2,TCF7L2,SZT2,HEY2,TMOD1,TNS1,FAM155A,MVB12B,PAK5" Drug 4660_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "DPF1,ASPHD1,APBB1,EPB41L5,ARRB1,CDK13,KIF1A,SCAPER,IFFO1,DCC,C2CD2L,EDIL3,CELSR3,FGFR1,AGAP2,DCTN2,DPYSL4,GLYR1,GPR75,ATF7,PTGDR2,IGF1,KCNJ9,KCNMA1,KCNQ3,VWA5A,NCAM1,CNOT4,SNTG1,PCSK2,PFKFB4,RETREG1,PMP2,PRPH,C1orf54,MYH14,PAQR6,MRAS,DOCK10,SLA,PKNOX2,SLC12A4,WDTC1,ARC,SYN2,SMG6,PCDHGB6,ZNF34,MAP3K12" Drug 2440_DN Niridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABHD6,APC,CACNA1A,HIP1R,MAP7,COL9A2,CREM,CRY2,CSNK1E,EFNA3,EFNB3,ING4,MRNIP,CDKL3,F5,FHL1,FOXG1,AGAP2,IQCG,PDLIM5,SEPT9,LILRA2,SPACA9,TJAP1,ITGA7,MAP4,MEF2C,NCAM1,NDUFA5,NEFH,CNOT4,PLCB2,MAPK7,MAPK10,PTAFR,PTPRO,EMID1,ITSN1,FAM102A,SMTN,SNCA,IZUMO4,RAP1GAP2,NCDN,ADGRL3,TCF7L2,KCTD2,CABIN1,RBFOX2" Drug 6474_UP Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABHD6,ACTN2,SEMA6A,BEGAIN,ATP1A2,SGCE,RUNX1T1,CLGN,CHRNB2,CRMP1,PDE4DIP,PHF14,SPOCK2,ATN1,EGR3,TPK1,HBS1L,GALC,ALDH1L1,SRCAP,C1QL1,NR3C1,ICA1,ITGAM,KCNMA1,LIG4,MAPT,MBD1,NF1,CNOT4,CDK18,LRRN3,PTHLH,CEP97,CLIP1,PPP4R3A,ZSWIM8,ATP10B,POPDC3,KAZN,TRIM2,PCDHA6,HEY2,KCTD2,WIPF1,LAT2,XRCC4,ADAMTSL3,DPF3" Drug 4570_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "C1QTNF1,MRTFA,BIN1,CNTNAP1,APC,CDK13,SLC4A4,ARHGEF7,BTRC,FOXN3,CHM,HOMER3,AATK,DCAF4,SGSM2,EDIL3,CNNM1,FAM13A,ELAVL3,C1orf61,CSPG5,C1QL1,MAP4K5,BACH2,DHX35,HSF2,SHISAL1,LIG4,LYRM9,ODF2,PAK3,PDE1C,CDIP1,PROX1,CNNM2,SAMD9,PID1,GAL3ST4,SCN8A,ASAP3,BCAN,SLC4A3,ZNF334,ARHGEF9,SYT1,DNAH7,PLPPR2,EPM2A,TIGD6" Drug 832_UP Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "KCNAB2,APBB2,ALDH4A1,SLC2A11,CFLAR,CACNA1G,OSGIN2,CBFA2T2,SRSF11,CLU,COL9A3,RIMS2,DNAJC6,SPOCK3,F3,ZNF44,HBS1L,DISC1,SPACA9,GRM8,BTN2A1,KCNH2,ADAM22,PFKFB2,RETREG1,SAMD9,C1orf54,KHDRBS2,GTDC1,ROBO1,SCN2B,ZNF821,FRMPD1,FAM214B,BTBD7,SLC20A2,TSPYL2,CLSTN2,DIP2A,TACC1,FAM208A,KIAA0930,TCF7L2,SSBP2,VAV2,TFIP11,ITM2C,EPM2A,ZNF248" Drug 7029_DN Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADD3,BRAP,CDC42BPA,BCAS1,PPFIA3,ATP2B1,KIF1A,CFLAR,CAMK2G,ENTPD6,SOCS6,MAP4K4,HOMER3,CTH,EDRF1,TBC1D5,DBN1,DSCAM,SORBS3,ANKMY1,ATP2C1,BTN2A1,RNFT2,KHK,MAP4,MIA2,MSRA,SSH1,LRRC49,TMEM104,RGS3,RNASEL,SUPT20H,ITSN1,ABLIM3,EPN2,BTBD7,EMC1,IQSEC2,PDLIM2,SATB2,TCF7L2,PSD3,BEX4,TRPC1,VGF,LMF1,MAP3K12,HPS4" Drug 5446_DN Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASPHD1,ASIC1,AP2A2,APP,PDE8B,SLC4A4,CFLAR,SCAPER,GYG2,BTRC,CFAP410,CLGN,TAOK2,HOMER3,GIT2,RCAN1,SORBS3,ANKMY1,FGFR1,IQCG,SEMA4D,CGREF1,GRB10,GRIK5,HNMT,IL6ST,KPNA5,LMO2,KITLG,MMP16,ADAM22,ZNF862,PTHLH,RGS12,SLC6A8,KDM4B,INKA2,TTBK2,VPS13A,MCF2L,EXOC7,RPGRIP1L,PSD3,SLC44A1,TK2,PARD3,TRPC1,ZFP37,EPM2A" Drug 1697_UP Triamterene [396-01-0]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "APC,APLP1,PLA2G4C,SLC4A4,SLC2A11,ATP6V0A1,SYNJ2,CDH2,TAOK2,SLC4A8,GPRASP1,SMG7,KBTBD11,EFNA3,HSD17B14,LRRC23,GPR153,GAP43,GNG4,GPD1,GPR37,ATXN2L,HNMT,TJAP1,MAN2A2,ZNF862,NFYA,NTRK2,PCDH9,PURG,MBOAT7,POLG,PRKAR1B,MAPK7,RAD52,RGS10,SH3BP2,PREX2,USP33,SOX10,ARHGAP26,SPART,TROVE2,ACSBG1,TRPC3,VIPR2,NDRG4,REEP1,SCG2" Drug 3475_UP Cromolyn disodium salt [15826-37-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "LTBP4,APBB2,PPP4R4,ALDH4A1,CFLAR,CBFA2T2,NEURL1,B4GALT6,ABCG1,CSNK1E,PHF14,GREB1,ARHGEF4,NOS1AP,CDON,GNE,HIPK3,VPS26C,FGFR1,GPER1,INPP5B,JAK2,KCNF1,KCNN1,NF1,SERPINE2,PLXNB1,LRP12,MBOAT7,TNPO2,MAPK7,RAB5B,RPS6KA2,TRAPPC13,SEMA6D,ANKRD6,TMCC1,ZC3H13,SS18,TBL1X,KIAA0930,AP4E1,SLC44A1,TRIO,ZMYND8,MICAL1,XRCC4,ZIC3,WNK1" Drug 2727_DN Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,AMPD3,BIN1,CDC42BPA,APAF1,APOC1,PPP4R4,FUBP1,HIP1R,EPS15L1,ZFYVE9,IQCK,NRG2,CREM,SIPA1L1,MFAP3L,EFNA3,CELSR3,LPAR6,LRRC23,RRAGB,F5,ZNF589,PDLIM5,KHDRBS3,ZMYND11,SRCAP,ZNF276,GPR75,GNG4,LILRA2,TJAP1,MAP4,AFF1,NF1,PCDH9,SMIM7,POU6F1,RAB3IL1,ZNF821,SH3BP2,ARHGAP26,DDN,TROVE2,KIAA1107,TCF7L2,CRTC1,CLIP2,MAP3K12" Drug 5888_UP Mesalamine [89-57-6]; Up 200; 26.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SLC12A5,AP2A2,PPP4R4,ARRB2,CFAP410,CACNA1A,ARHGAP33,ZFYVE9,QKI,AKAP7,ARHGEF10,BRINP1,RABGAP1L,MBNL2,LPAR6,TNK2,HSD17B14,TUBD1,FGF1,ADAM28,GNAO1,PRRC2B,GPR37,GRM8,GSTM5,VWA5A,MAPT,MOBP,MYO7A,NRCAM,PDE4B,RETREG1,NECAB2,RAD51D,FBXW7,IL17RB,NLGN1,DZIP1,MYH15,IFT122,LIMCH1,TSNAXIP1,HECW1,ARHGAP26,CAMTA2,SLC44A1,RIMBP2,XRCC4,NT5M" Drug 4734_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG3,NDRG2,LTBP4,MRTFA,DOC2A,TRMT9B,FAM131A,CDC14B,PLA2G4C,ATP2A2,CA4,ADGRG1,TAOK2,PLAA,CNTNAP2,RIMS2,NOS1AP,MFAP3L,ATN1,DSCAM,EDNRA,HSD17B14,DLC1,PDLIM5,USP19,TDRKH,STON1,GRM1,MEF2C,MID1,MYT1,NFYA,RETREG1,MBOAT7,POLG,PPP5C,RAB3IL1,PEX26,LIMCH1,DOP1A,UNC5B,MAPK8IP3,STX1A,PLCB1,ROBO3,PCDHA5,THRA,TRIO,SPHK2" Drug 3830_DN Solasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ACTN2,ADRA1D,MRTFA,APAF1,APBB2,GAS7,ARHGDIG,MARK4,SLC4A4,SCAPER,SYNGR3,ASIC3,DNAJB5,SH2B1,RIMS2,SLC12A6,EFNA3,LRRC23,EZH1,F3,KAT8,GFER,POLL,KCNH2,ADAM22,RETREG1,SNRK,ZSCAN2,RAB3A,RAD52,ZMAT4,RGS3,EMID1,SH3BP2,FAM214B,SHANK2,SNCA,DOP1A,KDM4C,ARHGAP26,MAPK8IP3,STX1A,EXOC7,CRTC1,CHST8,TGFBR3,TNS1,VIPR2,LAT2" Drug 5686_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "MRTFA,ANK3,APOC1,PDE8B,CA4,SRSF11,PLAA,BAG4,SIPA1L1,SDC3,GIT2,ZNF804A,RCAN1,DTNA,EFNA3,ZNF589,BAIAP2,GALC,INPP5K,GLYR1,CLASRP,KCNF1,LSS,MDM4,KITLG,MITF,ADAM22,ZNF862,NDUFA5,PLXNB1,MINDY2,PRKAR1B,ZSCAN32,PEX5,ZDHHC14,FERMT1,SYBU,SLC1A7,BTBD7,ZHX3,THSD1,VPS13A,EXOC7,NSD1,RUNDC3B,FAM155A,LMF1,EVI5,EPM2A" Drug 7277_DN Azapropazone [13539-59-8]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NCOA1,ATP2A2,AP4M1,RCBTB2,QKI,CSNK1E,PARD6A,SGSM2,OPTN,EFNA3,EPHA5,RRAGB,SCARA3,IQCG,ANKFY1,EFCAB2,INPP5K,GBX2,GLYR1,LPAR4,SLC2A6,MBD1,ZNF862,NDUFA5,ODF2,PBX1,RAD52,RALGDS,ZDHHC14,RGS10,TMEM156,SUPT20H,ASAP3,COA1,ZBTB43,COLGALT2,FCHO1,PHLDB1,ARHGEF9,KAZN,EXOC7,TIAM1,TNS1,ZKSCAN5,FAM155A,OSBP2,UPF3A,EVI5,ACTR3B" Drug 3473_UP Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AK2,C1QTNF3,LTBP4,GAS7,ATM,ATP6V0A1,CFLAR,SYNJ1,SYNJ2,MTMR3,HIP1R,ENTPD4,ABCG1,CSF1R,GREB1,DCAF8,MAML1,PLEKHA1,VPS13B,FGFR1,IQCG,ZNF44,ATP8A2,GLYR1,GNAS,IL6ST,INPP5B,MATK,AFDN,MPP2,ADAM22,PCDH9,MINDY2,ELOVL2,ZDHHC14,GSTCD,CLIP1,SUPT20H,SH3BP2,COA1,SMARCD3,ZHX3,SPTAN1,EXOC7,KIAA0930,DICER1,ZMYND8,REEP1,WNK1" Drug 1182_DN "estradiol, USP; Down 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,ALAD,CDK10,NCOA1,NUMB,N4BP2L1,CFLAR,SLC25A14,CD86,TPP1,ENTPD4,VCAN,HP1BP3,DPH1,RCAN1,FCF1,ING4,TXNL4A,LILRB4,LILRA2,ICA1,KIF2A,LIG4,VWA5A,LSS,MITF,NF1,SLC11A2,OCRL,PIK3R1,PLCB2,PMS2,PTPA,RAB3IL1,CEP97,RALGDS,RAP1GAP,TRIM68,TCP11L1,GALNT10,KIF1B,IQCE,TCF4,KAT6B,UBTF,FLRT2,WNK1,MAP3K12,PRDM2" Drug 2560_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,KIDINS220,AGT,ADGRF5,ANK3,DDO,AZGP1,CACNA1G,CA12,BRSK2,CLU,TCEAL2,NCOR2,NCAN,BRINP1,ST8SIA3,EGFR,AASS,ERBB2,DCTN2,FYB1,LYVE1,RUNDC3A,GLI2,PRUNE2,PCLO,GRIK5,GPR45,KLF12,HNMT,TJAP1,KCNJ5,MAPT,MSR1,OPRL1,PROX1,PTPRG,EPN2,PKNOX2,SNCA,ACSBG1,TACR1,WSCD1,SYNE1,ICAM5,RBFOX2,TRO,TRPC3,BEST1" Drug 2852_DN Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AP2A2,KCNAB2,FAM131A,MARK4,ST3GAL5,CRLF1,TAOK2,RAB28,QKI,AKAP7,ARHGEF4,DNM1,TRAPPC9,EIF4G2,DMTN,ACSL4,CAMSAP1,FHL1,DPYSL4,SRCAP,POLL,CACFD1,NF1,PDE4A,PRPH,RAB3A,RAP1GAP,SBF1,ITSN1,SLC1A7,FAM214B,BTBD7,EMC1,MAPK8IP3,TTBK2,ARC,EXOC7,KIAA1107,ARHGEF12,ATP13A2,AP4E1,TPM1,PLPPR2,VAV2,MICAL1,LMF1,ZFP37,SYNC,IFT88" Drug 2795_DN Palmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "C1QTNF3,APBB2,GAS7,BCAS1,ALDH4A1,SYNJ1,SYNJ2,ARHGEF2,PLEKHB1,FAM189A2,HOMER3,CSF1,PPP6R2,RIMS3,MFAP3L,EFNB3,LRRC23,EZH1,FOXG1,GPR153,INPP5K,AHDC1,HNMT,KCNH2,LMO2,MOBP,ZNF862,NF1,RETREG1,LRP12,MBOAT7,WDR25,RIPOR1,ZCWPW1,RGS10,SH3BP2,ABLIM3,SLC1A7,SLC20A2,ERC1,FCHO1,MCF2L,CRTC1,MICAL1,KCNK12,SPHK2,GDPD5,NAV2,SENP7" Drug 5339_UP Hemicholinium bromide [312-45-8]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADORA1,AK2,APC,GAS7,MADD,MARK4,CACNA1I,SCARB1,CDC27,CACNA2D2,SULT4A1,LY86,IFFO1,C2CD2,CYBB,HDAC4,DRD1,NCALD,F3,KAT8,ZNF589,BAIAP2,OGA,BTN2A1,INPP5B,MAP4,ADAM22,ZNF862,NACA,NPTX1,NTRK2,PC,PRODH,ROBO1,WLS,ZNF821,ZFP30,SH3BP2,ITSN1,ZKSCAN3,ZHX3,ZSWIM8,UNC5B,DAAM2,TRPM2,XRCC4,NDRG4,HPS4,MPPE1" Drug 2843_UP Cefaclor [70356-03-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASIC1,NDRG2,APBB2,APC,CDC14B,ATP2A2,SLC2A11,PROM1,BMP7,CAMK2B,SYNGR3,ZFYVE9,NECTIN3,CREM,SH2B1,CTIF,CNIH3,RABGAP1L,DMPK,EGFR,STX2,FGFR1,BAIAP2,CAP2,SEMA4D,EFCAB2,GPR153,GAB1,GLS,IL6ST,KCNN2,KCNQ3,MMP17,NF1,NPTX2,OGG1,CNNM2,PTHLH,RAD52,RPS6KA2,SNCA,SOX3,THSD1,TRIO,FAM155A,LAT2,PRDM2,ITM2C,KAT6A" Drug 2441_UP Amphotericin B [1397-89-3]; Up 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "APC,SEMA4G,PDE8B,CFLAR,CFAP410,CACNB2,CHRNB2,CREM,CSF1,PDE4DIP,DAPK1,SPOCK2,DBT,PLEKHO1,TBC1D16,PTK2B,KIAA1109,CAMKK2,TRAF3IP2,GAP43,ADAM28,RND1,GPR75,GUCY1A2,SLC2A6,HTR2A,KCND3,KCNN1,NPPA,P2RX7,PDE4B,PDE4D,PFKFB4,MINDY2,WLS,ZNF821,SLC1A3,KDM4D,SHANK2,COA1,WDTC1,SPP1,ZC3H13,CAMSAP2,TEX15,ZNF34,TJP1,TMOD1,KLC2" Drug 4538_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASIC1,CDC14B,ALDH4A1,CDH10,NRXN3,ZFYVE9,CREM,CNTNAP2,SDC3,HDAC9,ZFYVE16,ARMCX2,SMG7,SIDT2,EFNA3,SUGP2,WAC,FGFR1,BAIAP2,TRMO,GAD1,TMEM8B,DISC1,GLS,GPM6B,GPR17,STON1,IFI16,TJAP1,ODF2,SMIM7,ZSCAN32,FAT4,ROGDI,RGS10,SUGCT,FBXW7,LIMS2,KBTBD4,IFT122,THSD1,CEP68,IQCE,SZT2,TFIP11,NT5M,MPPE1,SMIM8,TIGD6" Drug 6781_UP Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SLC12A5,AGT,KCNAB2,ARHGAP5,RGS20,ADAM23,CFLAR,CA4,CACNB2,HAP1,PDE4DIP,RIMS2,MBNL2,ENO2,STX2,FHL1,PDLIM5,GPR153,NSG1,RND1,GRIK5,NR3C1,GRM1,ICA1,MAP2,NPTX1,PIK3CD,PLCB2,LRP12,ZSCAN2,TCP11L1,CNKSR2,FAM214B,SLN,INKA2,ARHGEF9,DMXL2,CRTC1,DICER1,CHST8,TK2,TMPO,R3HDM1,TPD52,CHST5,TRO,RPRM,LAT2,EPM2A" Drug 5861_DN Diclofenac sodium [15307-79-6]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABR,AP2A2,ANK3,APP,ALDH7A1,CFLAR,C5,CLU,SLC4A7,BAG4,TENM4,C2CD2L,SGSM2,EFNA3,RBM12,STX2,ACSL4,EFEMP1,SEC23B,TRMO,GLRB,PRRC2B,IFI16,KIF2A,SMAD1,TAGLN3,NFYA,PBX1,CCSER2,SLC25A23,LRP12,MBOAT7,MINDY2,PTPA,PPP3CC,KLK6,ELOVL2,GTDC1,ATXN7,AMBRA1,SMTN,PDZD2,MAPK8IP3,MMS19,IQCE,ATP13A2,TRIO,CADM1,NUP214" Drug 1505_UP Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SEMA4G,SYNJ1,SCAPER,CACNA1I,CACNA1G,CA4,CDH8,DNAJB5,QKI,LY86,ABI3BP,NCOR1,OSBPL3,RIMS2,HDAC4,DAPK1,MFAP3L,DUSP9,EIF4G2,SPEG,ZNF589,FLNC,CGREF1,RUNDC3A,POLL,GRM1,NXPH3,ADAM22,ZNF862,NEUROD1,NNAT,NOVA2,NUCB1,PACSIN1,CEP41,PRKCB,PRODH,CEP97,ZFHX4,CARF,RASA3,SYBU,TTBK2,GPR161,BEX4,RUNDC3B,WIPF1,KCNK12,XRCC4" Drug 2288_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASIC1,ABHD6,AMT,CDC42BPA,APBA2,CFLAR,BTRC,CA12,RUNX1T1,ARHGAP33,RCBTB2,CNTN1,SLC4A7,BAG4,SH2B1,EDRF1,MAML1,MFAP3L,ATN1,SORBS3,IQCG,SRCAP,GLYR1,TDRKH,GRIK5,ICA1,ADAM22,NF1,NUMA1,FAM120C,RAB3IL1,ZCWPW1,ZNF821,SH3BP2,BCAN,RCOR3,VPS13A,FBXW11,TBL1X,DOCK9,PCDHA6,TK2,PARD3,ZMYND8,MICAL1,ZBTB14,ZNF24,SLC30A3,PHTF2" Drug 3121_DN (1)-Nipecotic acid [498-95-3]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "GRAMD1B,PLA2G6,C1QTNF3,MARK4,NFS1,SCARB1,NMT2,HOMER3,IQCK,CSF3R,CSNK1E,CTNND1,DGKG,DBT,DCTN1,GSDME,FCGRT,KIAA1109,CAMSAP1,CSPG5,GPR19,PCLO,IRAK3,VWA5A,AFDN,ZNF862,OXTR,PDE4D,PLEC,MAPK3,PTAFR,RGS10,SH3BP2,ANKRD6,TMCC1,WDTC1,ZCCHC24,ZSWIM8,SUPT5H,KAZN,EXOC7,DNMBP,CAMSAP2,SYNE1,ZMYND8,HIRA,NPDC1,ATP6V0E2,GDPD5" Drug 6057_DN Foliosidine [2520-38-9]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "PLA2G6,ALCAM,SRPX,SEMA7A,APBA2,GAS7,SEMA4G,CACNA1D,SEPT7,CHRNB2,TAOK2,CRMP1,CSF1,SDC3,KBTBD11,SLC12A6,TOM1,EFNA3,EFNB3,FAM49B,CGREF1,GAD2,HBS1L,GLS,GRM1,ITPKB,MAP2,ADAM22,ZNF862,NEK1,CNOT4,LRP12,PPP5C,PRPH,SEMA6D,SBF1,PPP1R9A,ASAP3,TSNAXIP1,KDM4C,VAMP1,PLCB1,COBL,KAZN,KIAA0930,TCF7L2,AHCYL2,GPR161,TK2" Drug 6462_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SERPINA3,MTUS1,MRTFA,AMPD3,BIN1,CAPRIN2,CFLAR,GYG2,BTRC,CAMK2B,CLU,BAG4,PDE4DIP,GIT2,SMG7,TOM1,OPTN,TRMO,PRELID3A,DISC1,MALT1,TXNL4A,TDRKH,PADI2,IGSF1,KCNF1,VWA5A,MGAT3,NF1,NPTX1,PDE4B,PLEC,PTPRE,RGS3,RPS6KA2,ZNF365,SHANK2,SCMH1,CXXC4,ERC1,ITPRID2,ASTN2,MCF2L,THRA,TK2,UBTF,SYNC,SEMA3B,SSPN" Drug 590_UP 3-aminobenzamide; Up 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADD2,NCOA1,BAIAP3,HIP1R,CBFA2T2,TBRG4,TAOK2,CNTFR,ENTPD4,TBC1D5,SIDT2,EGR3,RGS17,EIF1,ENO2,FGFR1,FGFR3,BAIAP2,TRMO,ALDH1L1,IRF8,VWA5A,MAPT,MBP,NELL2,NPPA,NPR2,OCRL,ODF2,PBX1,EPN1,TNPO2,LRRN3,MAPK3,PRPH,PTAFR,KCTD17,PAQR6,FOXRED2,ZNF821,AMBRA1,EPN2,FAM214B,CDK5RAP2,SNCB,IQCE,ATP13A2,ZMAT3,KCNAB1" Drug 1883_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; PC3; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "C1QTNF1,ANK3,EIF4G3,ATP2B1,WASF1,CDC27,SOCS6,CNTFR,COL4A5,CRMP1,SIPA1L1,FAM169A,ZBTB24,SRGAP3,EFNB3,TNK2,SEC23B,UFM1,STAG2,CRCP,GLS,TDRKH,NXPH3,KTN1,CLDN11,PACSIN1,PPM1B,PPP2R5C,C1orf109,ARID4A,RGS4,NUDT11,ATXN7,SLC1A3,SON,DOK5,ZHX3,BEX1,NXT2,STX1A,SEZ6L,TMPRSS5,UBE3A,UCHL1,DNAJC12,LMF1,VSNL1,XRCC4,ZNF189" Drug 3238_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,NME5,C1QTNF3,ALCAM,MRTFA,BIN1,APBB2,APC,GYG2,CA4,SLC16A4,NEURL1,ADGRG1,CHRNA4,AKAP7,BAG4,NECTIN3,VCAN,EDRF1,EFNB3,SPEG,FGFR1,HBS1L,ERAP1,GATM,ATXN2L,ITGA7,KCND3,LIFR,CNOT4,MTRF1L,MAPK7,RAB3A,MYH14,SH3BP2,ASAP3,ANKRD6,SLC6A8,ARHGAP26,CDK19,JMJD6,OBSL1,TEK,ICAM5,TNS1,PRMT8,TRPC1,PRDM2,SMIM8" Drug 3368_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SYN3,ASIC2,NDRG2,C1QTNF1,BCL2L2,CACNA1I,KALRN,CBARP,TAOK2,COL9A3,DAPK3,KLHL3,EDN1,EGFR,DMTN,PTK2B,C1orf61,GAD2,ERAP1,DISC1,RUNDC3A,GNAO1,GPER1,GRIK5,NR3C1,HLF,KCNMA1,MSR1,TAGLN3,NCAM1,NNAT,OPRL1,CDIP1,C19orf57,MAPK7,SAMD9,PTPRZ1,ZNF493,SLC1A6,KDM4B,KIF21B,IZUMO4,DOCK9,TRH,FLRT2,LAT2,KCNAB1,MVB12B,PARP11" Drug 3309_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,AMPD3,APBA2,APBB2,APC,CDC14B,CFLAR,CFAP410,CACNB2,CBFA2T2,WHRN,RCHY1,CSF1R,CNTNAP2,SDC3,CTIF,MFAP3L,RABGAP1L,EIF4G2,ING4,NCALD,GAB1,GABRG2,TRAF3IP2,GPM6B,GRIK5,ATXN2L,IL6ST,KCND3,MAP4,ADAM22,CLDN11,PLCD1,STRN3,MAPK8,PTHLH,RAD52,C1orf54,KCNIP1,RYR1,SLC1A7,COA1,PEG10,POPDC3,ROBO3,KIAA1107,TCF7L2,SYNE1,HEY2" Drug 2382_DN Bufexamac [2438-72-4]; Down 200; 18uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "KIDINS220,ALK,MRTFA,CDK10,ASPH,NCOA1,NUMB,MAP7,SRSF11,SOCS6,TAOK2,TMEM184B,OSBPL3,SLITRK5,ZNF337,TM9SF4,TRAPPC9,SORBS3,HBS1L,GART,ALDH1L1,SRCAP,AHDC1,MSL3,PRRC2B,IFI16,LIG4,MAP4,NF1,CNOT4,OGDH,RALGDS,RET,PAQR6,SLA,BTBD7,KIF1B,DDN,FCHO1,DIP2A,STXBP1,FBXW11,HIF3A,SIRT1,TK2,RBFOX2,VIPR2,PRDM2,HPS4" Drug 6293_UP Melatonin [73-31-4]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NME5,PLA2G6,ALK,SEMA7A,ASCL1,NRP2,BAIAP3,CACNA2D1,CAMK2B,INA,TAOK2,COL9A2,TBC1D5,CTIF,SGSM2,TUBD1,RASL10A,ZNF44,GAD1,SESN1,USP19,GLI2,CNTRL,SPACA9,CACFD1,KLF12,HNMT,ITPKA,KCNJ5,KIFC3,MAPT,MYT1,ODF2,SERPINI1,PPP2R2B,SAMD9,RGS10,RGS12,TTLL7,STUM,DDN,PHLDB1,SYN2,KIAA1107,DOCK9,CRTC1,NT5M,STMN4,KCNAB1" Drug 4206_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADRA1D,TRMT9B,APC,ARRB2,DNAJB5,NRG2,HAPLN1,RGS6,ARHGEF10,ATN1,LRRC23,FYB1,GAB1,DISC1,SEPT9,GRIK2,GRM1,GRM8,SOX21,SHISAL1,MGAT3,TAGLN3,ZNF862,NRGN,ODF2,PBX1,PDE4D,ENPP2,SLC25A23,PLXNB1,MAPK7,PTPRB,ZCWPW1,KHDRBS2,RGS4,MRAS,FRMPD1,KANSL3,MYH15,SOX2,DDN,VAMP1,THRA,ZMYND8,VIPR2,NT5M,SCG2,VPS35L,KCNAB1" Drug 2331_UP Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABHD6,TRMT9B,EPB41L5,CA12,CACNA1A,RUNX1T1,SEPT7,MICAL2,SLITRK5,ZNF337,BRINP1,KIAA0753,DYRK1A,ANKFY1,ATP2C1,KHDRBS3,GABRA2,ZMYND11,INPP5K,WASF3,LILRB4,RASSF8,KCNC1,VWA5A,MYT1,NPR2,NLE1,SLC25A23,PPP2R5C,PTCH1,TMEM206,FRMPD1,FNDC3A,SLC15A2,SNCA,TROVE2,SYN2,TCF4,TCF7,TCF7L2,TEX15,DNAH7,TJP1,TK2,TMOD1,CDK20,TRPC3,HIRA,LAT2" Drug 2627_DN Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADD3,AK2,CDC42BPA,ARHGDIG,ADAM15,BCL7A,MTMR2,MAP7,FAM189A2,VAX2,QKI,IQCK,DBT,HP1BP3,FBXL5,G3BP2,DTNA,FCF1,TNK2,MRNIP,EZH1,FECH,FHL1,MSL3,RNFT2,AGFG1,KCNJ3,MATK,NF1,NFYA,NRGN,ODF2,PLEC,PTCH1,RALGDS,SUPT20H,EPN2,ELMO2,SOX3,NXT2,NCDN,PDLIM2,IQCE,TMPO,TPD52,MICAL1,LMF1,XRCC4,MPPE1" Drug 3533_DN Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AK2,PPFIA3,ARRB1,MARK4,CAMK2G,SOCS6,PLAA,QKI,SLC4A7,BAG4,ABCG1,CSF1,PDE4DIP,DCTN1,RUSC2,DLG3,TSPAN5,EFNB3,ERBB2,ECSIT,NR3C1,MAN1B1,HSD17B1,HSF2,MATK,MPP2,GIT1,NF1,RALGDS,RGS3,RGS10,CCDC25,WLS,BTBD7,UNC5B,DIP2A,STX1A,ARHGEF9,ASTN2,ATP11A,IQCE,SATB2,TCF7L2,ZKSCAN5,ZBTB14,MAP3K12,EVI5,RNF170,SSPN" Drug 4578_UP Apigenin [520-36-5]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "PLA2G6,C1QTNF3,TRMT9B,APBB1,GAS7,PRX,CADM3,N4BP2L1,MTMR3,CACNA1G,CACNG1,HAP1,LARGE1,TAOK2,RAB28,AKAP6,CRMP1,CNTNAP2,CTNND2,SPOCK2,C2CD2L,SHANK1,DTNB,SEMA3D,RASGRP2,CDKL3,ZNF44,HBS1L,HPCA,KCND3,NOVA2,PALM,PDGFRA,PENK,MAPK10,RASGRF1,PAQR6,SELL,RASA3,SCG5,FRMPD1,CNKSR2,SLC1A7,ZNF415,PHF24,CBX5,PRDM2,KCNAB1,HRASLS" Drug 4196_DN Benperidol [2062-84-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "PPFIA3,ARRB2,CFLAR,CCNT1,LHX2,NRXN3,DNAJB5,RGS6,VCAN,SPOCK3,EXOG,ATN1,DTNA,MBNL2,LRRC23,MTSS1L,ST3GAL6,GAB1,SEPT9,LPAR4,GRIK2,GRM1,GRM8,SCIN,MAP4,MAPT,NF1,ODF2,PBX1,PROX1,BCAS3,PTPRB,RAD52,RGS10,FBXW7,SBF1,ATXN7,SLC1A7,FAM214B,KANSL3,ASTN2,THRA,TIAM1,TIMP4,TK2,ZMYND8,VIPR2,KCNAB1,MPPE1" Drug 1516_DN Loxapine succinate [27833-64-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "MRTFA,DOC2A,APOC1,PPFIA3,CFLAR,PLEKHB1,NCOR1,DZIP3,SDC3,DCAF8,KIAA0586,FBXL5,DMPK,SORBS3,EIF5,EPB41L1,F3,ACSL4,EFCAB2,FAM49B,B4GALNT1,CNTRL,CACFD1,MAP4,MPP2,GIT1,LYRM9,PDE3B,SSH1,APTX,WDR25,TMEM231,RGS10,ROM1,FOXRED2,AMBRA1,EPN2,WDTC1,EMC1,SPTAN1,TSPYL2,CAMTA2,NCDN,MAPK8IP3,PLCB1,SYT1,TCF7L2,TMEM121,NPL" Drug 4087_UP Solanine alpha [20562-02-1]; Up 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "DPF1,ANK1,GAS7,GYG2,KCNAB3,RAB33A,VAX2,CNTN1,AKAP6,CTNND2,C2CD2L,ARNT2,DSCAM,FAM198B,C1orf61,AGAP2,PRELID3A,OGA,FYB1,SIGLEC8,SRCAP,LYVE1,ATF7,GRM7,KCND3,KCNF1,KCNN1,KIT,MMP16,NOVA2,PDE4A,NECAB2,SPATA6,MAPK8,CCDC40,TMEM206,TCP11L1,SCN2B,SH3BP2,NTNG1,SLC6A11,KIF13A,ZC3H13,RBM26,SPART,AP4E1,MKRN3,PRDM2,SLC17A6" Drug 5943_UP rotenone; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ACTN1,ALCAM,LTBP4,MRTFA,DOC2A,TRMT9B,MARK4,ALDH4A1,ADAM15,BAIAP3,SPAG9,CACNA2D2,PDE4DIP,EDRF1,TOX,DAPK1,CTIF,DTNA,DYRK1A,OPTN,EFNA3,AASS,ENO2,REEP2,PDLIM5,TMEM8B,ELOVL5,ICA1,ITIH2,MAPT,MMP17,PDE1C,TTLL7,TMEM206,RYR1,SH3BP2,ASAP3,SLC2A5,WDTC1,SPTAN1,POPDC3,KAZN,TRIM2,TMEM121,GPR161,VGF,MICAL1,XRCC4,SLC30A3" Drug 3933_UP Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "APLP1,ASCL1,RUNX1T1,SEPT7,CRLF1,KIAA1549L,PICK1,SNCAIP,CSF1,DCAF4,NTM,ELAVL3,MTSS1L,ERCC2,REEP2,ZIC4,KIAA1109,FYN,SIGLEC8,PTGDR2,IFI16,ITGA7,KHK,L1CAM,TAGLN3,NPR2,NTRK2,TREM2,CAMKV,PLCB2,PTPRB,GAL3ST4,RFX2,KLHL11,KIF21B,ARHGAP26,ATP11A,SMG6,DOCK9,DNAH7,TMOD1,TNS1,VAV2,CLIP2,XRCC4,MKRN3,SLC30A3,SCG2,SLC17A7" Drug 3758_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ARID1A,CDC42BPA,KCNAB2,GAS7,ZSCAN18,ADAM23,BMP7,SCAPER,BTRC,ARHGEF2,NIPBL,AKAP5,CRMP1,HAPLN1,DLG3,TOM1,ING4,SPEG,ETV1,PTK2B,EFCAB2,NEU3,GFER,CACFD1,TJAP1,ITPKA,VWA5A,NF1,PDE4D,GON4L,SNRK,BEND5,RGS10,TMEM206,ASAP3,PEX26,ATP10B,MAPK8IP3,SYT1,KIAA1107,GPR161,TIAM1,TNS1,CDK20,HIRA,VGF,XRCC4,WNK1,TIGD6" Drug 283_UP quercetin dihydrate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "CDK10,AZGP1,BCL7A,SYNJ2,CD86,ADGRG1,TAOK2,SLIT2,NIPBL,COL4A5,C2CD2L,SMG7,MED12,SIDT2,EFNB3,MBNL2,EFEMP1,SEC23B,TRMO,SEPT9,GLYR1,ICA1,MBD1,MYO6,NUCB1,PBX1,PLEC,PTPA,RAB3IL1,FAM192A,FOXRED2,SBF1,ASRGL1,SH3BP2,ITSN1,ABLIM3,TMCC1,KDM4B,EMC1,NXT2,SEPT8,ARHGEF9,COBL,ANKRD12,CABIN1,VAV2,SF1,GDPD5,MPPE1" Drug 3673_DN Ofloxacin [82419-36-1]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASIC1,APAF1,APP,CDK10,MARK4,RAB28,PLAA,NMT2,RAB26,NCOR2,PHF14,TBC1D5,ARMCX2,DMPK,CDON,EZH1,ATP8A1,ZNF589,FGFR1,FYN,TRAF3IP2,MSL3,ACOT7,INPP5B,KCNJ5,MAPT,NDP,CNOT4,SLC11A2,NUCB1,PPARA,CNTLN,CCDC40,ATXN2,FNDC3A,TNIK,SS18,CEP68,ARC,COBL,EXOC7,TRIM2,TPM2,ZMYND8,RPRM,VAV2,VGF,LAT2,NSD2" Drug 5386_DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SEMA6A,ALCAM,APLP1,PPFIA3,CDC14B,BRINP2,ALDH7A1,CFLAR,BTRC,CA12,B4GALT6,SLIT2,ZFYVE9,PLAA,QKI,MICAL2,DAPK3,SMG7,GNE,MRNIP,LRRC23,ACSL4,GALC,GNG4,GRIK5,HSF2,IGSF1,KCNH2,KCNJ3,LSS,MDM4,NEK1,NPR2,MBOAT7,PPP2R5C,ELOVL2,FAM120C,PEX5,RPS6KA2,EPN2,WDTC1,TTBK2,IQCE,TRIM2,TGFBR3,TK2,KCTD2,ZKSCAN5,VGF" Drug 2388_DN Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "CDK13,MARK4,ZBTB10,NCOA1,NUMB,SCAPER,FOXN3,SOCS6,ARMC8,CSF1R,SPATA2,DNM2,ABI2,KCTD3,DCTN4,F3,AHDC1,TXNL4A,LILRA2,GPR22,EML4,ITGAM,KIF2A,MAP4,CNOT4,PDE3B,PDE4B,SAMD9,TMEM231,RALGDS,TRAPPC13,PPP4R3A,RAB3GAP1,KDM4B,ARHGAP26,SRPK2,THSD1,MAPK8IP3,TTBK2,DIP2A,STXBP1,KAZN,TCF4,TCF7L2,TNS1,RBFOX2,NSD2,FTSJ1,WIPF2" Drug 6698_DN Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ALAD,TRMT9B,CDC42BPA,APP,PDE8B,MARK4,EIF4G3,ST3GAL5,SYNJ2,SCAPER,KRIT1,CDC42,LRRFIP1,FOXN3,NRXN3,RAB26,NCOR2,ARMCX2,SGSM2,SIDT2,CELSR3,COQ7,SCARA3,AFF2,ATP2C1,GAB1,ERAP1,INPP5K,GPM6B,NOS1,SLC11A2,PAK3,RETREG1,FA2H,MAPK7,WDR25,C1orf54,ZNF671,MAPK12,FBXO11,MYH15,SPTAN1,DDN,THSD1,NCDN,TMEM121,TK2,LMF1,WIPF1" Drug 6323_DN Cefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABR,MTUS1,C1QTNF1,BIN1,APC,MARK4,MYRF,SEPT7,NCOR2,SIPA1L1,PDE4DIP,DCAF8,SPOCK2,DLG3,OPTN,SORBS3,DENND4A,ANKMY1,TUBB4A,FGF1,ANKFY1,SRCAP,RASSF8,KCNMA1,MBD1,MPP2,TAGLN3,NDUFA5,FSD1,PPARA,PPP5C,CNNM2,GON4L,RAD52,FUZ,AMBRA1,NLGN1,TMCC1,ERC1,SPTAN1,IQSEC2,ZBTB43,SRPK2,ELOVL4,TBCEL,KIAA0930,PLPPR2,TFIP11,SCG2" Drug 4200_DN Idoxuridine [54-42-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABR,PLA2G6,TRMT9B,APOC1,PDE8B,KIF1A,CCNT1,RGS6,ARHGEF10,SNPH,ATN1,SUGP2,SORBS3,EPB41L1,MTSS1L,FOXG1,CINP,FYB1,GAB1,ZNF44,LPAR4,GRM1,SOX21,RASSF8,MAPT,MGAT3,NRGN,NUMA1,ODF2,PBX1,RETREG1,PTPRB,SBF1,ASAP3,FUZ,SLC1A7,KANSL3,BTBD7,MYH15,WDTC1,DDN,VAMP1,GPR161,TIAM1,CABIN1,ZMYND8,VIPR2,KCNAB1,NUP214" Drug 3271_DN Brompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "KIDINS220,ALAD,APC,APOC1,PPFIA3,CDC14B,CFLAR,SCAPER,GYG2,CACNA1D,SLC4A8,PPP6R2,NR1D2,FEM1B,EGFR,IRAK4,FECH,FGFR1,CAMSAP1,FAM49B,GPR153,TXNL4A,GLS,GSN,MPP2,SLC11A2,PPP3CC,RGS10,RXRA,SBF1,ZNF821,SGK1,SH3BP2,WDTC1,ZCCHC24,ZHX3,SS18,KANK1,ANKRD12,MTCL1,EXOC7,TIAM1,CABIN1,VAV2,ZNF189,HPS4,SEMA3B,NAV2,EPM2A" Drug 5061_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ARID1A,APC,SLC4A4,CBFA2T2,ARHGEF2,SOCS6,CLCN4,HOMER3,CNTNAP2,HDAC9,ARHGAP24,RABGAP1L,TOM1,EDIL3,HIPK3,RGS17,LRRC23,SPEG,ETV1,ZNF589,TRAF3IP2,GAD1,GUCY1B1,INPP5B,SCAMP5,PAK3,PLXNB1,BCAS3,CNTLN,PTHLH,FAT4,ROGDI,RXRA,MAPK12,DZIP1,PEX26,SMARCC2,TMCC1,TNIK,EMC1,SS18,NXT2,NCDN,ELOVL4,ROBO3,ARHGEF12,TK2,OSBP2,LMF1" Drug 2282_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADRA1B,TRMT9B,AMPD3,GAS7,ATP2B2,SYNJ2,CFAP410,USP2,CBARP,TAOK2,RAB33A,ZFYVE9,CLTB,PLCH2,RIMS2,SNPH,MAGI2,SMG7,DMD,SGK2,DLC1,SCARA3,FLNC,B3GAT1,SEPT9,C1QL1,GPER1,GRIK1,GRM8,IL11RA,ITGA7,PDE4D,GPR85,POU3F2,MASP1,RAD52,RASGRF1,SLC25A36,ZFHX4,DOCK10,PKNOX2,SLC11A1,SPP1,EXOC7,WSCD1,DMXL2,TNS1,UGT8,FLRT2" Drug 2015_UP Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; HL60; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABAT,CDC42BPA,APOC1,CDK10,ARNTL,ARRB2,ATP2B1,BCL7A,CFLAR,OSGIN2,RAB29,CAST,SCARB1,ARHGAP33,SLC4A7,SOCS5,PPP1R16B,TNK2,RASGRP2,KIAA1109,ATP2C1,FYB1,STAG2,ZMYND11,IRAK3,ATXN2L,VWA5A,NTRK3,PDE3B,PDE4D,PFKFB3,CCSER2,RETREG1,PPM1B,PPP2R2B,TCP11L1,LGR4,ATXN7,ITSN1,ELMO2,KDM4B,FCHO1,SYT11,AGTPBP1,FBXW11,HIRA,XRCC4,EVI5,SLC17A7" Drug 4747_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG3,KIDINS220,NME5,TRMT9B,BIN1,AMT,GAS7,PLA2G4C,MPDZ,BTRC,TAOK2,QKI,FEZ1,NOS1AP,MAML1,ING4,DMTN,NCALD,C1orf61,TRMO,DISC1,INPP5K,POLL,GRB10,MEF2C,MMP16,ZNF862,NF1,NFYA,RGS3,GSTCD,SBF1,SELL,SH3BP2,WDTC1,ZHX3,CEP68,NSFL1C,EXOC7,SZT2,CHST8,TK2,TMOD1,KCTD2,TNS1,RUNDC3B,HIRA,LMF1,MPPE1" Drug 3435_UP Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AMPD3,APBB2,PPFIA3,PPP4R4,SYNJ2,SCAPER,BTRC,CACNA1D,FOXN3,TPP1,PICK1,DCAF8,DAPK3,CTIF,MFAP3L,LYPD1,RCAN1,DTNA,DTNB,TSPAN5,EFNA3,FHL1,ANKFY1,HBS1L,DISC1,GCNT2,TXNL4A,ATXN2L,HSD17B1,KCNJ3,VWA5A,MBD1,BCO1,PLEC,PMP22,ASAP3,SLC1A7,ZSWIM8,EMC1,FCHO1,CEP68,ATP11A,IQCE,UBE3A,VGF,SYNC,WNK1,MAP3K12,SSPN" Drug 6653_DN Bezafibrate [41859-67-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "PLA2G6,APOC1,BRINP2,FOXN3,HAPLN1,CNTNAP2,GIT2,MBNL2,PLXNC1,TENM1,EPB41L2,CDKL3,ZNF589,ANKFY1,SEPT9,SRCAP,GLYR1,KCNMB4,GPR37,KHK,MEIS1,MMP16,LYRM9,NF1,CNOT4,PLCD1,PLXNB1,MAPK7,CNNM2,CNTLN,PID1,ZCWPW1,TTLL7,MYH14,NEK11,RPS6KA2,ZNF821,ZFP30,ASAP3,IQSEC2,CEP68,SYT1,SMG6,SLC44A1,TRIO,VGF,XRCC4,HPS4,PHTF2" Drug 3580_DN Mephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "C1QTNF3,ALCAM,APBB2,GAS7,PPFIA3,CDK10,NUMB,CFLAR,CAMK2G,SOCS6,ENTPD4,NOS1AP,JAKMIP2,MFAP3L,ATN1,SIDT2,ANKMY1,ACSL4,BAIAP2,NOP56,PDLIM5,USP19,ZNF276,MAP4K5,RASSF8,ADAM22,NEK1,NF1,CCSER2,RETREG1,PLXNB1,PACSIN1,GON4L,RAB3A,ATG16L1,FAM184A,EMID1,FOXRED2,SLC6A8,ZCCHC24,ATP11A,EXOC7,KIAA1107,SMG6,CRTC1,CABIN1,CDK20,VAV2,MICAL1" Drug 5624_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,ADRA1D,AP2A2,PLA2G6,BIN1,MARK4,BMP7,CHRNB2,STOML1,SULT4A1,SOCS5,PDE4DIP,SDC3,DCAF4,ATN1,EFNA3,MRNIP,CAMSAP1,AFF2,OGA,GAB1,GLYR1,CACFD1,BTN2A1,NEUROD1,PDE3B,LRP12,MAPK7,SAMD9,TMEM231,RAB3IL1,RGS12,BCAN,RPH3A,RBM34,WDTC1,EMC1,KDM4C,SPART,ATP11A,TCF7,TGFBR3,TNS1,TRIO,RUNDC3B,TRPC1,ZNF711,PRDM2,KAT6A" Drug 6368_UP PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ACTN2,ALK,APC,DNAH17,CFAP410,CAMK2B,CHN2,CABP1,NRG2,ATRNL1,C2CD2L,LYPD1,ATN1,USH1C,EFNB3,ELN,KCNMB2,NCALD,FYB1,GLI2,LILRA2,SOX21,SHISAL1,TAGLN3,ZNF862,NF1,NPPA,PDE4B,PDE4D,LRRN3,CEP41,MARCH1,PID1,RASGRF1,BEND5,ZNF821,ANKRD6,SLC11A1,DOP1A,SPTAN1,SYT1,TPM1,TPM2,TRO,TRPC1,CA14,VGF,XRCC4,ZIC3" Drug 5563_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG2,PLA2G6,BIN1,ARHGDIG,CRLF1,RCBTB2,SLIT2,TPP1,FAM189A2,SLC4A7,SDC3,PPP6R2,HIPK3,EFNA3,KAT8,FGFR1,BAIAP2,FHL1,DPYSL4,PRELID3A,RAB30,POLL,RASSF8,KCNH2,VWA5A,MID1,NF1,NFYA,NOS1,SLC11A2,NRGN,NUCB1,SETD4,RETREG1,POLG,PRPH,SAMD9,TMEM231,FBXW7,SBF1,WDTC1,PHLDB1,MCF2L,WSCD1,CRTC1,AHCYL2,CDK20,REEP1,MPPE1" Drug 4644_UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "APOC1,AQP4,CDC14B,DDX3Y,NOL4,CACNA1I,CACNA2D1,RUNX1T1,CDH10,CHN2,EPS15L1,AKAP6,SEC14L5,MFAP3L,ST8SIA3,PLXNC1,CALCRL,SPEG,EZH1,FGFR1,AFF2,TBR1,CPLX2,GPR75,LILRA2,HLF,LMO2,NCAM1,NOVA2,NPTX1,PENK,SPATA6,POU3F2,PPP1R1A,PTPRG,MARCH1,C1orf54,SUSD4,MRAS,SLC11A1,KIF21B,SPTB,VAMP1,TACR1,DOCK9,TNS1,SEZ6L,VIPR2,PARP11" Drug 2335_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "NDRG3,NDRG2,ALK,MRTFA,MARK4,ALDH7A1,CFLAR,SYNJ2,C5,CDC42,SLC4A7,CSF1,SIPA1L1,KIAA0753,CNNM1,MRNIP,CDKL3,ZNF589,FOXG1,GPR153,DISC1,TJAP1,LSS,MAPT,MOBP,GIT1,NELL2,NINJ2,NNAT,NPR2,P2RX7,MTRF1L,PTAFR,FBXW7,SEMA6D,GALNT10,FERMT1,SLC15A2,BTBD7,SNCA,KIF1B,KAZN,TBL1X,NSD1,CRTC1,VGF,SPHK2,ZBTB38,WNK1" Drug 4582_UP "Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "DPF1,ADD2,C1QTNF3,CCDC181,ST3GAL5,FUBP1,LDB2,CREM,SH2B1,RIMS2,RIMS3,CTIF,NTM,DTNB,ELN,LRRC17,MTSS1L,ETV1,REEP2,ST3GAL6,DCTN2,CACFD1,SOX21,HLF,IGFBP1,KCNC1,MGAT3,MOBP,MYT1,PDE3B,PDE4D,PDGFRA,GPR85,MINDY2,CNNM2,PTPRG,PTPRH,RGS10,CARF,KIRREL1,FOXRED2,NTNG1,SOX15,MAPK8IP3,ADGRL3,WWC1,REEP1,ZNF225,EMSY" Drug 4083_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "RALGAPA1,BIN1,CDC42BPA,APBB2,ARRB2,ASTN1,KIF1A,BCL2L2,ST3GAL5,SYNJ2,BTRC,MAP7,CLCN4,STOML1,WHRN,SLC4A8,TCEAL2,NCOR2,SLITRK5,TOX,LYPD1,FGF1,POLR1B,GLYR1,GNAS,PCLO,GRM1,KLF12,MOBP,PDE1C,PIK3R1,RETREG1,NLE1,PRKAR1B,GRAMD1C,SH3TC2,MYH14,SH3BP2,PPP4R3A,SLN,LHPP,CEP68,ASTN2,GPR161,TIAM1,TMPO,TNS1,MICAL1,LAT2" Drug 6182_DN nordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ACTN2,ADD2,ANK3,APOC1,ALDH4A1,CAMK2B,REPS2,EPS15L1,ZFYVE9,AKAP7,SH2B1,DZIP3,PHF14,KIAA0753,DTNA,ST8SIA3,EDNRB,DLC1,KIAA1109,CAMKK2,CSPG5,POLL,GPR22,SOX21,IL6ST,SMAD1,MEF2C,MOBP,ZNF862,BCAS3,WDR25,RAB3A,RAB3IL1,ZDHHC14,RET,SH3BP2,SLC1A3,SLC11A1,ZHX3,DDN,NCDN,PLCB1,ATP11A,SZT2,PSD3,THBS4,TNS1,WNK1,NT5M" Drug 493_UP radicicol; Up 200; 0.1uM; SKMEL5; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "RBM10,ABHD6,NDRG2,PPFIA3,APP,ARHGAP5,ARNTL,ZSCAN18,CHRM4,CHRNB2,JAM2,DNAJB5,VCAN,ECE2,KLHL3,ING4,DCTN2,PDLIM5,ATP2C1,LILRA2,ADAMTS13,CACFD1,ITGA7,AFF1,NFYA,NPR2,NRGN,PALM,RC3H2,NUDT11,RNASEL,GSTCD,TCP11L1,HSPA4L,FBXO11,SMARCC2,MAPKBP1,SPART,LMO3,SS18,EXOC7,CBX5,ZMYND8,TST,FLRT1,ZNF32,SPHK2,HPS4,LAS1L" Drug 1512_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AK2,OGT,FAM131A,ATM,SLC4A4,CFLAR,BTRC,CACNA1D,SRSF11,RAB28,ZFYVE9,ARMC8,ZNF337,FBXL5,C2CD2L,SMG7,RCAN1,FEM1B,EZH1,FER,SEMA4D,GLYR1,CNTRL,DIDO1,RNFT2,LIG4,MBNL1,MPP2,NLE1,STRN3,LRP12,WDR25,TCP11L1,SEC14L1,ZNF821,FBXO11,UNC5B,CLSTN2,ELOVL4,ARHGEF9,PLCB1,EXOC7,IQCE,METTL3,SSBP2,REEP1,SEMA3B,SMIM8,PHTF2" Drug 4667_DN Azathioprine [446-86-6]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADRA1D,MTUS1,NME5,PPFIA4,PPFIA3,SLC4A4,LDLRAD4,SCARB1,ARHGEF2,AKAP7,NRG2,VCAN,PDE4DIP,KIAA0513,BRINP1,RUSC2,SMG7,ATN1,EDNRA,FGFR1,SCARA3,GRM1,MAPT,MDFI,MITF,NF1,OPCML,PDE4D,PIK3R1,SLC25A23,STRN3,TMEM231,KHDRBS2,RGS4,ZFP30,FRMPD1,SLC4A3,EPN2,SLC20A2,TNIK,ARHGAP26,SYT11,TCF4,AP4E1,TK2,AMACR,WIPF1,KCNAB1,NUP214" Drug 1414_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; HL60; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADD2,OSBPL1A,AK2,APBA2,MTMR2,LDLRAD4,CACNA1A,PICK1,AKAP6,C2CD2L,PARD6A,NR1D2,EIF5,IRAK4,ELN,C1orf61,CELF1,ALDH1L1,SRCAP,PCDH17,DIDO1,ADAMTS13,PTPRT,KCNN2,MEF2C,SLC11A2,SETD4,OCRL,CLDN11,P2RX7,SMIM7,MAPK10,CNNM2,BCAS3,C1orf109,MYH14,DBNDD2,SPTB,TSPYL2,THSD1,VPS13A,KAZN,DDHD2,WWC1,EHBP1,ARHGEF12,FLRT2,WRN,PRDM10" Drug 5022_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AP2A2,NME5,BIN1,AMT,APBA2,APP,CA4,CACNA1D,HAP1,KYAT1,RCBTB2,STOML1,ARMC8,NECTIN3,ENTPD4,CSF1R,RIMS2,PPP6R2,DAPK3,MFAP3L,KIAA1109,FGF12,FGFR3,DPYSL4,PRELID3A,TRAF3IP2,CNTRL,TJAP1,MMP16,MSI1,ADAM22,ZNF862,PDE4A,PLCD1,WDR25,NKAIN1,RAB3A,RAB3IL1,SLN,SOX3,SPTAN1,PHLDB1,ASTN2,EXOC7,IQCE,PSD3,TGFBR3,XRCC4,UPF3A" Drug 3259_UP Cefadroxil [50370-12-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "MRTFA,CDC42BPA,PPP4R4,ASPH,ALDH4A1,ATP2A2,SLC2A11,INA,CLGN,TAOK2,DNAJB5,RIMS3,DTNA,HIPK3,CNNM1,OPTN,F3,ZNF589,GLYR1,GLS,GPER1,MAPT,MDM4,MEIS2,KITLG,ADAM22,ZNF862,NF1,NOS1,NUMA1,PLCD1,STRN3,NECAB2,MINDY2,MAPK7,RAD52,PAQR6,ITSN1,SHANK2,TROVE2,SZT2,ARHGEF12,PCDHA5,ZNF34,TK2,KCTD2,EMSY,MVB12B,KAT6A" Drug 5604_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AK2,LTBP4,APBA2,GAS7,PDE8B,MARK4,SLC2A11,SYNJ1,GYG2,KYAT1,STOML1,CRY2,FAM169A,PPP6R2,MFAP3L,C2CD2L,MAGI2,ATN1,DTNA,HIPK3,TNK2,MRNIP,GPR153,SRCAP,ADAM28,GNG4,GPM6B,GRIK5,KCNH2,KIF5C,VWA5A,NRGN,LRRN3,TMEM231,EMID1,KCNIP1,SH3BP2,ASAP3,FAM214B,LIMCH1,ASTN2,PCDHA5,AHCYL2,DICER1,CABIN1,CDK20,ZIC3,HPS4,SEMA3B" Drug 2240_UP Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "SYN3,AP2A2,MRTFA,AMPH,APC,GAS7,PRX,CDK13,ALDH4A1,CFLAR,BRSK2,NRG2,TENM4,DMPK,ATN1,EDNRA,MTSS1L,ANKMY1,ATP8A1,GABRA2,PCLO,HTR5A,IL11RA,NDUFA5,NELL2,NF1,NNAT,NOVA2,PLCB2,PACSIN1,MINDY2,MAPK7,PRODH,SAMD9,ZMAT4,TMEM206,SCN8A,SH3BP2,SH3GL3,ST6GAL1,SLC2A5,MAPKBP1,CDK19,PCDHA5,R3HDM1,ZMYND8,UGT8,CLIP2,NT5M" Drug 2196_DN Ethotoin [86-35-1]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "PLA2G6,N4BP2L1,RIPK1,CFAP410,CACNA1A,CAPN3,SCARB1,HOMER3,SLC4A7,CSF1,PDE4DIP,ZNF337,TBC1D5,DAPK3,DBN1,RCAN1,DTNA,FRY,ABI2,EIF1,GPHN,ERCC2,VPS26C,KIAA1109,CAP2,GABRA4,TXNL4A,MAP4K5,IL6R,LIG4,LSS,MDM4,AFF1,N6AMT1,CCSER2,PTPA,SIDT1,ZDHHC14,C12orf49,FNDC3A,NUBPL,THSD1,ZC4H2,SS18,NXT2,RBFOX2,TSN,NSD2,MPPE1" Drug 1113_DN doxycycline; Down 200; 14.4uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "OSBPL1A,ANK3,CDK13,EIF4G3,MPDZ,SYNJ1,CCNT1,SYNGR3,CLTA,HINFP,APPL1,CTNND1,ZNF337,TM9SF4,KIAA0586,DBT,ZBTB24,G3BP2,DMTF1,SEZ6L2,GNAS,BTN2A1,MARK3,MKLN1,NAP1L1,CCSER2,SMIM7,ING3,BSDC1,ZDHHC4,RGS3,ITSN1,RAB3GAP1,KBTBD4,MYCBP2,SS18,NXT2,DIP2A,CAMSAP2,TBL1X,TCF7,TPM4,UBE2H,UBTF,MTCH1,WRN,WNK1,WIPF2,SMIM8" Drug 2551_DN Flumethasone [2135-17-3]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ALAD,NUMB,SYNJ2,CACNA1A,CACNB2,HIP1R,CD86,SCARB1,NMT2,HOMER3,IQCK,SLC4A7,CPS1,CSF1R,MICAL2,KIAA0753,RUSC2,NR1D2,CDON,MTSS1L,F8,EFCAB2,PDLIM5,ERAP1,INPP5K,COPS8,LILRA2,SLC2A6,NCKAP1L,IFI16,MEF2C,SLC11A2,OLR1,ENPP2,KCTD15,PLCB2,SIDT1,DEF8,TMEM231,CEP97,RAP1GAP,FBXW7,SEC14L1,ARHGEF40,WDTC1,FCHO1,DMXL2,TNNT1,LMF1" Drug 1867_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AP1B1,APC,ARRB1,ADAM23,MTMR3,CPS1,PPP1R16B,ZFYVE16,SMG7,DTNA,EFNA3,CELSR3,MBNL2,EIF1,SRCAP,MSL3,CACFD1,ELOVL5,LSS,MAP4,GIT1,NOS1,PENK,MAPK3,PTPRO,PEX5,PLEKHB2,RGS10,RNASEL,DOCK10,SLC20A2,TMCC1,WDTC1,CDK19,DDN,TROVE2,ZC4H2,STX1A,ARHGEF9,CAMSAP2,EHBP1,PSD3,TNS1,TPD52,TPM2,TRPS1,VAV2,VIPR2,SPHK2" Drug 1912_UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AMT,PPFIA3,RUNX1T1,CDH2,DNAJB5,B3GAT3,RUSC2,ATN1,DTNA,EDN1,EPB41L2,SCARA3,PDLIM5,SRCAP,GDF9,AHDC1,HTATSF1,MUM1,ARHGAP19,IL6ST,KIFC3,MYL3,MYO9A,NAP1L1,ZNF426,PRKACB,RIPOR1,SEC61A2,NEK11,FAM192A,SBF1,ATXN2,ZNF821,BCAN,WDR47,ARHGEF40,SMARCD3,WDTC1,ZHX3,LHPP,SS18,NXT2,TACC1,TK2,SEZ6L,TSC2,UBE3A,TFIP11,GDPD5" Drug 6988_DN clozapine; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AP1B1,OSBPL1A,CDC42BPA,PPFIA3,ARHGAP5,SCARB1,SRSF11,SOCS6,RAB28,HINFP,ZNF337,RIMS3,GIT2,RABGAP1L,DNM1,FGFR3,FYN,TXNL4A,PCSK1N,GPR37,MEIS2,MITF,NASP,NRCAM,OXTR,CCSER2,PPP2R5C,PRKAR1B,PRODH,CNNM2,TMEM260,RAD51D,SH3BP2,FERMT1,FNDC3A,SMTN,BTBD7,CDK5RAP2,ZBTB43,EXOC7,TBL1X,SATB2,TCF7L2,TRIM2,CLASP1,UBE2H,VAV1,NDRG4,EPM2A" Drug 2133_UP Cinchonine [118-10-5]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ABHD6,APAF1,KIF1A,ADGRB1,CACNA1I,MAP7,SLC16A4,SEPT7,CDC42,CLGN,SLC4A8,CREM,EDNRB,HEYL,EIF1,FECH,KIAA1109,CAMSAP1,FHL1,FOXG1,NBEA,PRELID3A,GPR153,ADAM28,PCLO,IL6ST,ITIH2,KIT,NUMA1,PTPN13,BEND5,RGS10,KCTD17,TCP11L1,MAP6D1,FAM102A,SLC1A7,CCDC88A,SLC20A2,SOX10,IZUMO4,TSPYL2,INKA2,TBCEL,AHCYL2,HIF3A,SYNC,WNK1,SENP7" Drug 4439_DN prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASPHD1,ARID1A,NME5,PLA2G6,C1QTNF3,LTBP4,ALK,APBB2,APC,PPP4R4,MTMR3,BAIAP3,CHN2,TAOK2,LHX2,CLCN4,STOML1,COL9A3,OSBPL3,SLITRK5,SMG7,FEM1B,MBNL2,PLXNC1,TUBB4A,SCML2,KIF2A,KITLG,MX1,LYRM9,PLCB2,CNTLN,RAB3IL1,RGS10,RGS12,KIRREL1,SELL,BCAN,SLC1A7,OGDHL,BEX1,IQSEC2,CEP68,TMPO,TNS1,VAV1,XRCC4,ZNF24,PARP6" Drug 4733_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADORA1,LGR5,ATP2B3,KSR1,SCAPER,BAIAP3,CAPN3,CBARP,DNAJB5,ARHGEF6,CNTN1,AKAP6,VCAN,DGKG,SPOCK2,RASGRP2,MTSS1L,IGSF6,ATP8A1,PRELID3A,CSPG5,SIGLEC8,LYVE1,LILRA2,GRIK5,SYNPO,IGFBP1,TJAP1,KCND3,KCNH1,KCNJ5,KIF5A,AFDN,MSR1,MYT1,NOVA2,OGG1,EPN1,SNRK,PTHLH,RGS4,TCP11L1,SYNDIG1,MRAS,KIF21B,PCDHGB6,AMACR,KCNK12,KCNAB1" Drug 5338_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "AMT,APC,RGS20,PDE8B,CFAP410,CHRNA4,C2CD2,FEZ1,DAPK3,GIT2,MFAP3L,RCAN1,KAT8,ZNF589,PRELID3A,GALC,SEPT9,POLL,KLF12,KCNH2,VWA5A,LSS,MAN2A2,MAP4,MITF,MPP2,NEK1,NF1,NLE1,PLEC,LRP12,PACSIN1,FAM120C,CEP97,RAD52,RGS3,NEK11,RPS6KA2,SLC1A7,CLSTN2,SS18,ADGRL3,TCF7L2,PARD3,PLPPR2,MICAL1,GDPD5,NAV2,MPPE1" Drug 5249_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ASPHD1,ALCAM,ASPH,CFLAR,CAMK2G,KRIT1,PLEKHB1,STOML1,QKI,HOMER3,TBC1D5,DBT,DTNA,HIPK3,ENO2,ACSL4,FGFR1,ANKFY1,TACC2,FAM49B,ZMYND11,GALC,MSL3,RNFT2,HMGCR,ITPKB,JAK2,MDM4,ADAM22,CNOT4,SLC11A2,RETREG1,LRP12,PRKAR1B,RAB3IL1,ROBO1,FBXW7,PPP4R3A,UHRF1BP1L,SPART,THSD1,GANAB,PRRC2C,ASTN2,AP4E1,ZNF34,TMPO,RBFOX2,ZNF189" Drug 2229_DN Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ARID1A,NDRG2,KIDINS220,LTBP4,APC,PPFIA3,ATM,ATP6V0A1,CFLAR,ARHGEF1,SLIT2,PICK1,AKAP7,CRY2,CSF1,CSF1R,SEC14L5,SMG7,SPACA9,GSTM5,RASSF8,HNMT,INPP5B,KCNJ3,KIF2A,ADAM22,NF1,CNOT4,NUMA1,PALM,PRODH,PTHLH,GSTCD,FAM214B,BTBD7,SNCA,TROVE2,THSD1,PLCB1,ARC,ASTN2,PSD3,PCDHA6,ZMYND8,VLDLR,LMF1,SPHK2,SYNC,EMSY" Drug 2112_UP Nimesulide [51803-78-2]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 49 196 "ADORA2A,APP,CDK13,ZSCAN18,ALDH4A1,KIF1A,LARGE1,PLEKHB1,HOMER3,RCHY1,ARHGAP24,PLPPR4,MRNIP,NCALD,ZNF549,HPCAL4,SEPT9,GLYR1,GPD1,STON1,TPPP,CACFD1,GUCY1B1,BACH2,SMAD9,GIT1,NF1,NPR2,PAK3,CDIP1,MAPK8,CNTLN,RIPOR1,RAD52,RGS4,ATXN7,SLA,SLC1A7,ZKSCAN3,HECW1,SAMSN1,MCF2L,TBL1X,EHBP1,SEZ6L,VIPR2,VLDLR,ZNF24,SLC17A7" Drug 2861_DN Piracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "SEMA6A,APOC1,RASL11B,STX16,CFLAR,SYNJ2,CA4,KRIT1,SRSF11,SOCS6,CHM,PLEKHB1,RAB28,CLU,FAM169A,DBT,DNM1,TSPAN5,HIPK3,CDKL3,FGFR1,DISC1,GLYR1,HTATSF1,KCNMB4,TDRKH,GSN,MAP4,TM6SF1,PDPK1,PIK3R1,PRKAB2,MAPK8,ELOVL2,RAB3A,RGS3,SLC25A36,SEC14L1,TRA2B,FNDC3A,EMC1,ZBTB43,THSD1,STX1A,TBL1X,VGF,EMSY,EPM2A" Drug 3574_UP Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ABHD6,ARNTL,CDK13,ADGRB3,SYNJ2,CACNA1D,CHRNA4,QKI,HOMER3,CNTFR,COL9A3,RGS6,ARHGEF10,PDE4DIP,RIPOR2,ATN1,HIPK3,EFNA3,EFS,SPEG,ZNF589,KIAA1109,GAD1,TMEM8B,MALT1,HMGCR,ADAM22,NF1,NFYA,CNOT4,NUCB1,NLE1,RETREG2,MINDY2,ZMAT4,KLHDC8A,RPS6KA2,S100B,ASIC4,CPEB3,WDTC1,TSNAXIP1,IQSEC2,PLCB1,WSCD1,RUNDC3B,ZMYND8,SEMA3B" Drug 1563_UP Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ARID1A,SHTN1,ARNTL,N4BP2L1,WASF1,KRIT1,CCNT1,HINFP,PPP1R16B,C2CD2L,DPYSL2,BSCL2,FGFR1,SEC23B,SMC2,ATP2C1,OGA,MALT1,DIDO1,KTN1,LAMP2,MAP4,MBD1,NINJ2,PPP2R5C,PRKACB,CNNM2,MSANTD2,PAQR6,TMEM156,SGK1,KBTBD4,ELMO2,ATF7IP,KDM3A,CDK19,PBLD,VAMP1,FBXW11,TCF4,CLASP1,CBX5,TST,EVI5,LMAN2L,WIPF2,PDSS2,ST7" Drug 5581_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ADORA2A,C1QTNF1,ALK,AMT,ANK2,APAF1,SEMA4G,CDK13,CHI3L2,NRG2,CNTNAP2,GSDME,DPH1,DRD1,DTNB,EDNRA,ING4,KIAA1109,KHDRBS3,TMEM8B,GLYR1,GPR19,STON1,GPER1,GRM8,TJAP1,KCNN1,VWA5A,LYRM9,SERPINI1,LRP12,PKN2,PTHLH,TRIM68,RNASEL,RYR1,SH3GL3,SLC6A11,SLC11A1,WDTC1,CDK19,NPAS3,ARHGEF9,SEMA4A,TK2,R3HDM1,TRIO,PRDM10" Drug 3733_UP 0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ASPHD1,AMPD3,AQP4,DNAH17,ASPH,ADAM23,BMP7,BAIAP3,CACNG1,CD86,FOXN3,CHI3L2,TAOK2,RAB33A,CLCN4,SUSD5,EDRF1,GIT2,RBM12,EFNB3,LPAR6,OGA,SIGLEC8,SRCAP,DIDO1,KCNJ3,LSS,NPTX1,SLC11A2,OGG1,RC3H2,TNPO2,PBRM1,SEMA6D,RPH3A,SLC1A7,SLC11A1,RBM34,SCN3B,ZC3H13,ARC,AMACR,LAT2,PRDM2,KCNAB1,MVB12B,KAT6A,PHTF2" Drug 4582_DN "Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ABR,ADRA1D,AK2,C1QTNF1,APC,MARK4,ATM,STX16,CFLAR,SYNJ2,CDC42,PLEKHB1,TPP1,DNAJB5,ENTPD4,FAM131B,HP1BP3,CDON,EDNRA,SIDT2,SCML2,PDLIM5,FAM49B,ZNF44,LSS,GIT1,PFKFB2,MAPK7,PRPH,SNRK,ATXN7,ITSN1,FNDC3A,WDTC1,ZBTB43,LHPP,POGZ,SS18,ELOVL4,PHLDB1,KIAA1107,SIN3B,DOCK9,TRIO,ZMYND8,KLC2,WNK1,MAP3K12" Drug 4298_DN 3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.01E-04 1.00E+00 3.98E-03 4.53E-02 48 191 "ACLY,NDRG3,CDK13,ASPH,ALDH4A1,ATM,STX16,KIF1A,ADAM15,CFLAR,IL33,SPAG9,CHM,HOMER3,CRMP1,DZIP3,HIPK3,EGFR,SORBS3,ING4,RGS17,FGFR1,FHL1,ANKFY1,FAM49B,FYN,GART,GRIK5,SOX21,GUCY1B1,NXPH3,ATXN2L,HSF2,INPP5B,ITIH2,LIG4,CNOT4,CLDN11,ZNF426,PROX1,SEC61A2,POGZ,ATP11A,TMPO,TNS1,SSBP2,WNK1,SEMA3B" Drug CID000133976 alpha-sialylcholesterol Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "CACNA1A,CACNA1B,CACNA1E,CACNA2D1,FGF1" Drug DB00371 Meprobamate Drug Bank 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5" Drug CID000042106 tiapamil Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "CACNA2D1,DMD,ABCB1,PIK3C2A,SYNE1" Drug CID000004047 mefruside Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "SLC22A6,PTPN5,HP,HPR,KCNK3" Drug ctd:C029433 lead tetraacetate CTD 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "APP,NRXN1,TUBB3,MAPT,SYP" Drug CID000167721 didansylcystine Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "DTNB,TPM1,TPM2,TPM3,TPM4" Drug CID005310991 A-192621 Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "EDN1,EDN3,EDNRA,EDNRB,ST8SIA2" Drug CID000070194 NPOH Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "AASS,DNER,GPD1,GPD2,ADHFE1" Drug CID009549889 3-IN Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "TKTL1,ELAVL2,MOG,RYR1,UBTF" Drug CID006918393 YM928 Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "GRIA1,GRIA2,GRIA4,GRM3,PTCH1" Drug CID000097045 benzoylacetate Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "ABHD6,APP,SLC22A6,KCNK3,ANKS1B" Drug CID000583065 "3,4-dihydroquinazoline" Stitch 5.03E-04 1.00E+00 3.99E-03 4.54E-02 5 6 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1E" Drug CID005327099 AC1NS1NG Stitch 5.25E-04 1.00E+00 4.16E-03 4.73E-02 39 147 "LRRC7,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ST3GAL5,GYG2,CD81,CHRNB2,CTH,BOC,EGFR,ERBB4,ADGRV1,ATP2C1,FYN,GABRA1,GABRG2,GALC,B4GALNT1,SIGLEC8,NEU3,GCNT2,ITGAM,MAG,MOBP,MOG,OMG,PRKCB,PRKCG,PKN2,PRKCZ,SMPD3,FNDC3A,ST6GAL1,ST8SIA1,NEU4,FTSJ1,SIGLEC10" Drug CID000019688 norethisterone oenanthate Stitch 5.33E-04 1.00E+00 4.22E-03 4.80E-02 31 109 "SERPINA3,SLITRK1,ADORA1,ADORA2A,ADORA3,ADRB2,APBB1,APBB2,APLP1,APP,BCHE,CHN1,CNTNAP2,ENO2,BAIAP2,CYP46A1,GPR17,GRIN2C,GRIN2D,ITIH2,MAPT,NBL1,NPTX1,PMP2,RELN,PRIMA1,SNCA,PDZRN3,THRA,WNT7A,RTN4" Drug CID000002293 BAPTA-AM Stitch 5.35E-04 1.00E+00 4.24E-03 4.82E-02 68 294 "ADCY5,ADCY6,ADCY8,ATP2B1,ATP2B2,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CAMK2B,CAMK2D,KRIT1,AIFM1,CDC42,CHRM1,DBI,EDNRA,EGFR,PTK2B,PPP1R1B,ACTL6B,FOXO3,CAMKK2,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM8,HSP90AA1,KCNH2,KCNJ3,KCNJ5,KCNN1,KCNN3,OGDH,P2RX7,P2RY1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PLCB2,MBOAT7,PPP3CA,PPP3CC,PRKCB,PRKCG,MAPK3,MAPK4,MAPK9,MAPK10,PTK2,RYR1,RYR3,MAPK12,TMEM132D,PLCB1,ACTR6,CABIN1,TRPC1,UBC,P2RY12,SCG2,PLD4,CAMK1G" Drug ctd:C513428 pyrachlostrobin CTD 5.54E-04 1.00E+00 4.39E-03 4.99E-02 162 810 "ACTN1,ADORA2A,ADRB2,SNX32,KCNT1,DPP10,PPFIA4,DDO,IGDCC4,BCHE,RGS11,GPR146,PROM1,BMP7,C1QC,DDR1,CALB1,JAM2,TPP1,TJP2,CNN3,COL4A5,HS3ST5,CRHBP,AKAP12,CSF1,CSF1R,ARHGEF10,IPCEF1,CYBB,BOC,PHF19,SPOCK3,DLX1,HS3ST2,CDON,EGFR,AASS,LPAR6,SORBS3,RASGRP2,EFS,ADGRV1,EYA1,F3,F5,EFEMP1,FGFR1,FGFR3,AMOTL2,POLK,FLNC,PDLIM5,FYB1,MEGF10,NEK6,ERAP1,ARFIP1,GHR,DHRS4,GLDC,GLI2,PCDH11X,PSRC1,LILRB4,FUT10,STON1,PLCD4,PARD3B,GRIK1,GRIK3,GSN,SLC2A6,ATOH8,RASSF8,NXPH3,NXPH2,HNMT,IGFBPL1,HPCA,IL6R,IL11RA,ITGAM,ITGAV,KCNC2,TTYH2,LAMP2,MATK,MATN3,ADAM11,MEST,AFF1,CCDC80,MSR1,FXYD7,NFE2L2,DDR2,P2RX7,TREM2,ANLN,PLTP,PMP22,PRRX1,SPATA6,SEPT4,NXPH1,PRKCG,SYTL2,SIDT1,PTPN13,PTX3,NWD1,KLHDC8A,KIRREL1,EPHA10,LRRK2,SOX8,WLS,HKDC1,SLC1A6,SLC6A7,SLC12A4,SNCB,PALLD,ZCCHC24,SPP1,PEG10,ITPRID2,ST5,INKA2,SEPT8,KANK1,VAMP1,SLC37A2,SEMA4A,PDLIM2,TCF7,NACC2,ICAM5,TLR4,DAAM2,TNFRSF1B,TNS1,TPM2,TPM4,KCNE5,CA14,AMOT,PLEKHH2,WIPF1,ZIC2,ZIC3,CRB2,SYNC,WNK1,ADAMTS9,TMEM178A,SLC17A7,TMEM63C,ADAMTSL3,MSRB3,SSPN" Drug CID000000535 1-aminocyclopropane-1-carboxylic acid Stitch 5.62E-04 1.00E+00 4.41E-03 5.01E-02 32 114 "AK2,PDXK,NAE1,CALB2,RUNX1T1,CRY2,CSF1,CSF1R,CTNND1,CTNND2,ABI1,EDIL3,ACSL4,FDFT1,SEMA4D,GLRB,GPT2,GRIN2C,GRIN2D,HPSE2,MARK3,CTNNA3,PCMT1,PDGFRA,APTX,RIT2,PUF60,ANKRD12,MLST8,WDR7,UBC,HPS4" Drug 3672_UP Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DPF1,RALGAPA1,ADORA2A,ADRA1D,NME5,CDC14B,CDK10,SLC4A4,ATP6V0A1,CFAP410,CACNA2D1,HIP1R,RAB26,EDRF1,TOX,NRN1,DLC1,KIAA1109,CAMSAP1,NSG1,IQGAP2,RUNDC3A,RND1,GRIK5,GRM8,C2orf72,IGF1,KCND3,MYL3,NEUROD1,NOS1,PALM,PCSK2,POU3F4,PTPRD,FEZF2,DGLUCY,DOCK10,ARHGEF40,SLC11A1,KDM4B,SCN3B,INKA2,SYP,DOCK9,TEX15,PIK3R5,TPM2,SPHK2" Drug 4265_DN Succinylsulfathiazole [116-43-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "RALGAPA1,PLA2G6,ANK3,APBB2,APOC1,SHROOM2,CDK10,SEMA4G,ST3GAL5,BTRC,CHN2,RAB26,CNTNAP2,PLPPR4,ETV1,RRAGB,FGF1,FGFR1,C1orf61,PRELID3A,GABRA2,CNTRL,HNMT,SHISAL1,DIPK1A,TM6SF1,MIA2,MX1,NF1,CNOT4,PAK3,PIK3R1,PLCD1,RC3H2,PRPH,PTCH1,KCTD17,AP1AR,MAPK12,SCG5,SMARCD3,KIF13A,TCF4,CRTC1,WIPF1,XRCC4,EVI5,KCNAB1,PARP11" Drug 2573_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MTUS1,AMT,PPFIA4,APC,CDC14B,PDE8B,CAPN3,CDH10,CHN2,TPP1,VCAN,CTIF,SPOCK3,TNK2,RASGRP2,DLC1,ST3GAL6,KAT8,NEU3,ALDH1L1,POLL,CACFD1,ATXN2L,IL11RA,MID1,AFDN,MOBP,KCTD15,EPN1,LRRC49,PTCH1,PTN,CEP97,FRMPD1,FNDC3A,CNKSR2,LIMS2,IZUMO4,SPTAN1,DMXL2,CRTC1,CHST8,SLC44A1,TPM1,VIPR2,CLIP2,REEP1,EVI5,PCBP4" Drug 4709_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SLC12A5,APBB2,BMP7,GYG2,ARHGAP33,SOCS6,CLU,TPP1,NMT2,COL4A5,CRY2,CSNK1E,SIPA1L1,SOCS5,PDE4DIP,PPP6R2,ATN1,OPTN,HSD17B14,ENO2,COQ7,SCML2,ST3GAL6,BAIAP2,FYN,TRAF3IP2,SYT17,GLS,GNG4,TDRKH,KPNA5,MIA2,NF1,NUMA1,OGG1,PTPRE,MAPKBP1,SOX2,LHPP,MAPK8IP3,ZEB1,PSD3,SLC44A1,THRA,TK2,ZKSCAN5,FAM155A,VGF,WIPF2" Drug 4461_DN fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADCY6,CDC42BPA,APLP1,SCARB1,ARMC8,MICAL2,SLITRK5,PHF14,FAM131B,DCAF8,HIPK3,ZNF589,PDLIM5,TRAF3IP2,HBS1L,GLYR1,SCIN,IL12A,INPP5B,JAK2,KIF5C,LSS,MBD1,MDFI,MEF2C,KITLG,NFYA,OGDH,PBX1,PC,PEX5,RGS7,MYH14,ZNF821,SH3BP2,ASAP3,SMARCA4,EMC1,SPTB,MAPK8IP3,CEP68,WSCD1,ZEB1,GPR161,TNS1,TRPM2,NSD2,TFIP11,PHTF2" Drug 2059_DN Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ARID1A,BRAP,MTUS1,AMT,PPFIA1,APOC1,APP,MTMR9,CDK5R1,MTMR3,QKI,WHRN,CSNK1G3,SDC3,SNPH,ZFYVE16,SGSM2,SIDT2,ELAVL2,ENO2,DMTN,USP21,TPK1,FYN,INPP5K,ZNF276,PCLO,ICA1,TJAP1,MIA2,MINDY2,SYTL2,PTHLH,SFPQ,HSPA4L,ST6GAL1,FAM214B,KBTBD4,KDM4B,KDM4C,TSPYL2,CAMTA2,NCDN,SATB2,CLASP1,TRIO,KLC2,TFIP11,PLSCR4" Drug 4022_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ALK,APP,ASTN1,ATP2B3,KIF1A,NRP2,FOXN3,ARHGAP22,EPS15L1,PICK1,WHRN,PARD6A,EXOG,ATN1,PLXNC1,COQ7,MTSS1L,ETV1,TUBB4A,FGF1,AFF2,SYT17,INPP5K,GFER,ZNF276,GLI2,TDRKH,GRM8,MX1,NPR2,OPCML,EPN1,FA2H,POLG,TMEM231,SH3TC2,RGS10,KCTD17,MYH14,IL17RB,ASAP3,SLC1A7,MYH15,DNAH7,THRA,TK2,LILRA4,CADM1,UPF3A" Drug 365_UP "estradiol, USP; Up 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "KCNAB2,GAS7,BCAS1,CDK10,CADM3,CDH8,CHRNB2,PPP6R2,B3GAT3,ECM2,FEM1B,OPTN,EGR3,MRNIP,LRRC23,TMEM8B,SRCAP,GRIN1,NR3C1,SLC2A6,ARHGAP19,HMX1,ICA1,KCNJ9,MYL3,NF1,SETD4,PCDH9,PFKFB2,PLCD1,PLXNB1,MAPK8,RET,ZNF671,SSTR2,COBL,EXOC7,WWC1,WSCD1,ATP13A2,THBS4,RIMBP2,TNS1,TPM3,NR2C2,UGT8,WNT7A,SLC13A3,MPPE1" Drug 503_DN "indomethacin, USP; Down 200; 100uM; SKMEL5; HG-U133A" Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "RALGAPA1,ASIC1,MPDZ,B4GALT6,JAM2,TMEM59L,PCYT1B,CREB5,MFAP3L,C2CD2L,DRP2,ATN1,SIDT2,SORBS3,ELAVL4,EPHB1,CEND1,HPCAL4,B3GAT1,SYT17,MALT1,LYVE1,HPGDS,MCHR1,GRIK5,HNMT,KCNB1,STMN1,MGAT3,ADAM22,FXYD6,OGDH,OGG1,SYTL2,SPDL1,PYGM,RIPOR1,RGS12,FNDC3A,KBTBD4,MAPKBP1,ZSWIM8,SRPK2,TNR,TPM1,TRIO,SSBP2,MICAL1,TFIP11" Drug 2438_UP Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABHD6,ADORA1,AGT,C1QTNF1,RIPK1,ADAM23,THSD7A,RUNX1T1,CDH2,CHGA,CLCN3,CREM,ARHGEF4,CTNND1,CTNND2,RIMS2,EDRF1,DLG3,E2F5,LRRC23,CEND1,TBC1D16,OLFM1,GABRA2,GNAL,GPM6B,SCAMP5,CD200,LYRM9,NNAT,NRCAM,P2RY1,CCSER2,ST8SIA5,PLP1,PPP2R2B,MASP1,RGS4,SLC2A5,FAM214B,FAIM2,SEPT8,CAMSAP2,TCF7L2,CRTC1,FAM155A,NUP214,DPF3,SENP7" Drug 4766_UP Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "TKTL1,FGD2,APBA2,ARSE,CDK13,ASCL1,RASL11B,ATP1A2,ATP1A3,NRXN3,CLCN4,AKAP7,COL9A3,CRMP1,CSF1,ARHGAP24,PHYHIP,HIPK3,HEYL,FGFR1,ADAM28,RUNDC3A,RND1,RAB30,GPM6B,GRM7,GSN,GSTM5,IFI16,TJAP1,KCNJ5,MOBP,ADAM22,MX1,PKN2,MAPK10,C1orf54,SH3GL3,MAPKBP1,SNCA,ZCCHC24,ATP10B,MAPK8IP3,PCDHGA10,SYNC,SLC17A7,MVB12B,PLSCR4,JPH3" Drug 7168_UP Diazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "GAS7,PLA2G4C,ASPH,PTCH2,ATM,MPDZ,CFLAR,CBFA2T2,CLCN3,QKI,SLC4A8,AKAP12,NCOR1,SOCS5,PDE4DIP,RIMS2,RASSF2,DNAJC6,LYPD1,SGK2,MBNL2,DLC1,SEMA4D,GFER,COPS8,POLL,CACFD1,MDM4,MIA2,PCDH9,STRN3,SAMD9,GON4L,NEK11,RXRA,SYBU,SLC6A9,ZCCHC24,EMC1,KDM4C,SPART,CLASP2,INKA2,SEMA4A,AP4E1,TMPO,VIPR2,PRDM2,PHTF2" Drug 4613_DN Bepridil hydrochloride [74764-40-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MTUS1,PPFIA3,APP,LGR5,ARNTL,CAMK2G,SPAG9,NFS1,B4GALT6,SLC4A7,BAG4,GPRASP1,DBT,ATN1,TUBD1,RRAGB,ATP8A1,ZNF589,SCARA3,ANKFY1,DENND2A,INPP5K,GART,MSL3,GPD2,SHISAL1,NDP,NEK1,NFYA,PTK2,PTPN13,RGS10,SH3BP2,ASAP3,ELMO2,SMARCD3,LIMCH1,TNIK,THSD1,SS18,GSE1,ARHGEF12,AHCYL2,TK2,BEX4,NSD2,TFIP11,NT5M,FZD3" Drug 4583_DN Terconazole [67915-31-5]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADRA1D,KIDINS220,CDK10,SLC4A4,KIF1A,ADGRB2,NRP2,CACNA1A,CDC42,ARHGAP33,FOXN3,TPP1,HOMER3,PICK1,CREB5,AATK,ARHGEF10,SNPH,CTIF,CNNM1,ELAVL3,EN2,CINP,ELOVL5,HSF2,SCIN,ITPKB,MAPT,MITF,LYRM9,NDP,OPCML,POLG,ELOVL2,RAB3IL1,ZCWPW1,SUGCT,DCUN1D2,TCP11L1,IL17RB,ASAP3,ZNF334,LIMCH1,SNCA,ZHX3,DDN,VGF,XRCC4,PRDM2" Drug 3831_DN Deltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADORA2A,ADRA1D,ALCAM,MRTFA,BIN1,BCL7A,CA4,ARHGAP33,TAOK2,AKAP12,CSF1,SDC3,RIMS2,KBTBD11,CNNM1,MBNL2,HSD17B14,SRCAP,ATXN2L,IL6R,ADAM22,NPR2,NPTX1,PFKFB2,PLCD1,FSD1,PRKAR1B,SNRK,ZSCAN2,TMEM231,RAD52,ENOX1,EMID1,ZNF365,PREX2,SLC22A4,SNCA,SPTAN1,LHPP,CLSTN2,ST5,MAPK8IP3,SYN2,CHST8,TGFBR3,CABIN1,LAT2,ZNF45,SSPN" Drug 3214_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "RALGAPA1,ARID1A,ADD2,BIN1,ASPH,ATP1A3,SEPT7,AKAP7,BAG4,VCAN,ARHGEF4,PLXNC1,FAM198B,OLFM1,AFF2,FYB1,GAB1,SESN1,GNG3,PRUNE2,GRM1,AP4S1,KIT,MOBP,MYCN,NEFM,NFIX,NOVA2,NTRK2,EPN1,LRP12,PTHLH,ZSCAN2,ZMAT4,TCP11L1,SELL,SH3GL3,SNCA,SYT5,DOCK9,TMOD1,R3HDM1,TRPC1,WIPF1,KCNK12,WNK1,PRDM2,NT5M,JPH3" Drug 3693_UP 0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "GRAMD1B,FAM135A,SEMA7A,ATP2A2,SLC2A11,BACH1,BMP7,CACNG1,CBS,CHM,NRXN3,RAB26,HOMER3,CTNND2,PYGO1,KLHL3,ARNT2,EXOG,EDN1,FRY,AASS,SRPK3,SEMA4D,ANKFY1,RUNDC3A,GRK4,GRM1,GRM2,HTR2A,IGF1,ITGA7,LSS,MMP16,NF1,PCBP3,PDE4B,CAMKV,PIK3CD,FXYD1,SPATA6,RFX2,RFX5,SELL,KDM4B,PCDHA5,GPR161,TNS1,UCHL1,ZNF154" Drug 5467_UP Etofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "PLA2G6,LTBP4,ANK1,SEMA7A,ALDH7A1,MTMR2,BTRC,FOXN3,CNTFR,FRMPD4,TBC1D5,MED12,DMTN,EZH1,CORO2B,FGFR1,GABRA5,TXNL4A,GPM6A,NR3C1,IGSF1,ITIH2,KCNF1,KCNH2,KCNJ5,KCNJ10,KCNN2,VWA5A,MAP4,MATK,GIT1,NKX2-2,NTRK2,RETREG1,POU3F4,ZCWPW1,MRAS,ST6GAL1,SLC2A5,SCN3B,FNBP1,RGL1,ASTN2,SYT5,HIF3A,TNS1,TRPC1,MAP3K12,EVI5" Drug 2720_DN Isopropamide iodide [71-81-8]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SLC12A5,NUMB,ATM,SYNJ2,LDLRAD4,ARHGEF1,CLGN,EPS15L1,AKAP7,ARMC8,NRG2,ENTPD4,SH2B1,CSF1,PDE4DIP,RABGAP1L,SLC12A6,CDKL3,FHL1,FAM49B,OGA,SEPT9,GART,GPR75,MSL3,LPAR4,GRM7,MAP4,NDUFA5,SLC11A2,OLR1,PLTP,PRKCZ,PEX5,RAB3IL1,ZCWPW1,TMEM206,SEC14L1,ANKRD6,SLC11A1,RBM26,KANK1,RBFOX2,TPM3,PLPPR2,XRCC4,URM1,NLRP3,TIGD6" Drug 1515_DN Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ARID1A,DOC2A,ARRB1,SLC4A4,CFLAR,RAB29,REPS2,HOMER3,CRY2,SDC3,DCAF8,SMG7,DMPK,SUGP2,EPB41L1,ACSL4,GLYR1,CNTRL,NR3C1,TJAP1,MPP2,NAP1L2,SETD4,PIK3R1,NLE1,MBOAT7,GON4L,PTPRE,MSANTD2,RGS10,RNASEL,TCP11L1,SBF1,SEC14L1,FUZ,FBXO11,SLC1A7,EFHD1,SLC20A2,KDM4B,ELOVL4,ASTN2,ATP11A,TBL1X,AP4E1,PARD3,LMF1,MVB12B,ACTR3B" Drug 2620_UP Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADGRF5,FAM135A,TRMT9B,ANK1,SLC4A4,N4BP2L1,LDLRAD4,CA4,HIP1R,NRXN2,CSF1,CTNND2,DMPK,ST8SIA3,MTSS1L,EFS,KIAA1109,SORBS1,AHDC1,GFER,PCDH17,GPM6B,CACFD1,IRAK3,KIFC3,MSR1,ZNF862,NOS1,NPR2,NTRK2,NUMA1,PURG,MINDY2,MAPK7,ZNF493,RGR,PNMA8A,FRMPD1,FAM214B,PKNOX2,ZCCHC24,SPTAN1,RGL1,PHLDB1,SYT11,TK2,UBE3A,ITM2C,PHTF2" Drug 3199_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,MRTFA,TRMT9B,BCAS1,SEMA4G,SLC4A4,CFLAR,SYNJ2,CAMK2G,FAM189A2,FADS2,ARMC8,BAG4,CSF1R,ATRNL1,FAM169A,ARHGEF4,CTNND2,CYBB,CTIF,DTNA,ELAVL3,LRRC23,STX2,GAA,LPAR4,NR3C1,KCNH2,PCDH9,NLE1,MAPK8,RIPOR1,CEP97,RGS12,FOXRED2,ZNF365,INTS9,KIF13A,ACSBG1,ANKRD12,DOCK9,ZNF34,THRA,TRPC1,HIRA,PLPPR2,VIPR2,ST7,TIGD6" Drug 6222_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APOC1,ARRB1,PDE8B,ADAM15,CDK5R1,SYNJ1,ST3GAL5,CHRNB2,QKI,PDE4DIP,DZIP3,MFAP3L,SPOCK3,RCAN1,ING4,DMTN,LRRC23,DLC1,FER,OLFM1,MPP6,OGA,HBS1L,LYVE1,HTATSF1,GPR37,GRM8,IL6ST,INPP5B,MATK,NACA,NF1,NUMA1,GON4L,C1orf54,RNASEL,NEK11,SYBU,COLGALT2,SS18,TTBK2,TMPO,NR2C2,OSBP2,GDPD5,MPPE1,UBE3B,NUP214,SSPN" Drug 4727_UP Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,ADORA1,BBOX1,SEMA4G,ARRB1,MARK4,ATP2B2,CAMK2B,CHRNB2,NECTIN3,CSF1,RIMS3,GSDME,MTSS1L,PRELID3A,DISC1,RND1,GNG3,GPD1,PCLO,SPACA9,ADAMTS13,GRM7,ATXN2L,ITIH2,VWA5A,MAPT,OPCML,GPR85,PLTP,PURG,MAPK7,SNRK,ZDHHC14,RFX3,EMID1,SEMA6D,ASAP3,CNKSR2,KIF21B,ARHGAP26,PCDHGB6,TGFBR3,AMACR,WIPF1,KCNK12,SYNC,ITM2C,PLSCR4" Drug 4673_UP Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "BRINP2,ADGRB2,BMP7,BTRC,HAP1,CAMK2B,LDB2,CHI3L2,PLEKHB1,HOMER3,ABCG1,CSF1,TBC1D5,PLPPR4,ATN1,DTNA,EFNB3,ELAVL3,ETV1,OLFM1,GAD2,LYVE1,GLYR1,CACFD1,JAK2,LIFR,NCAM1,PCBP3,RETREG1,PPP5C,MAPK3,CNNM2,PTCH1,RAD51D,RAD52,GTDC1,RGS12,SELL,SUPT20H,PHLDB1,EXOC7,TBCEL,TCF4,CHST8,ZNF34,NSD2,ZNF24,PRDM2,MVB12B" Drug 2038_UP Danazol [17230-88-5]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP1B1,SYT13,PDE8B,SLC4A4,ADGRB2,CACNA1I,MYRF,CA12,CACNA1A,CALB2,SPAG9,CNTFR,IQCK,DCT,TMCC2,ELN,BAIAP2,ALDH1L1,GNG3,SPACA9,CACFD1,KCNF1,LAMA2,GIT1,SAMD14,NTRK3,OMG,PFKFB2,DUSP26,CAMKV,PACSIN1,RAP1GAP,RNASE1,RXRA,LIMS2,SLC6A11,SLC11A1,SLN,SNAP25,ZC3H13,SPTB,SYN2,LILRA4,ZMYND8,CA14,VGF,VIPR2,CAMK1G,NUP214" Drug 3056_DN S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADORA1,FAM131A,MADD,SYNJ1,CBFA2T2,LARGE1,CLCN4,NMT2,STOML1,NCOR2,ABCG1,CSF1,SLITRK5,DCAF4,RUBCN,EDRF1,DGKG,DLG4,DYRK1A,EGR3,SORBS3,RASGRP2,F5,DLC1,FER,PDLIM5,GABRA2,SEPT9,GPD2,LILRA2,KIF3A,HPCA,MAP4,MID1,LRRN3,PLPPR1,SYNDIG1,TNIK,VAMP1,TAL1,TCF7L2,TRIM2,SZT2,PSD3,TMOD1,SSBP2,CLIP2,ZFP37,SSPN" Drug 6924_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "C1QTNF3,SEMA6A,AMH,CDC42BPA,ANK1,APLP1,SCAPER,GYG2,CAMK2G,SLC16A4,DNAJB5,CNTFR,COL9A3,RCHY1,RIMS3,DRP2,MBNL2,DMTN,F5,C1orf61,SEMA4D,AFF2,GPR153,GCNT2,GFER,NR3C1,HTR2A,ITPKB,PACRG,MYCN,NOS1,NTRK3,ST8SIA5,PLPPR1,RGS10,RYR1,SLC6A9,KDM4B,ZSWIM8,RBM26,CLSTN2,MAPK8IP3,EXOC7,IQCE,AHCYL2,THRA,TRIO,KCNAB1,KAT6A" Drug 4803_UP Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SYN3,BEGAIN,APAF1,APC,PPP4R4,RASL11B,ATP6V0A1,BTRC,CFAP410,CACNB4,CALB1,CALB2,CBFA2T2,ARHGAP33,CHD5,VCAN,RIMS2,ZNF337,CTIF,GIT2,KBTBD11,ELAVL3,RASGRP2,PTK2B,CORO2B,KAT8,IQCG,POLL,GRB10,GRM1,KCNMA1,PALM,PDE4B,PLCD1,PPP5C,PTPRB,PTPRE,KCNIP1,SH3BP2,FNDC3A,SLC6A8,SLC20A2,SNCA,SYN2,POPDC3,TRIM2,TNS1,SSBP2,WNK1" Drug 2864_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DPF1,ADORA1,AP2A2,PLA2G6,BEGAIN,AMPD3,PRX,PPP4R4,FUBP1,CACNA2D1,CACNB2,CAMK2G,CDO1,ZFYVE9,SIPA1L1,RIMS3,DAPK1,SPOCK2,BRINP1,TMCC2,ERBB2,GLS,GPR37,ADAMTS8,ICA1,ITIH2,SMAD9,BCO1,TAGLN3,MYO7A,NEUROD1,NF1,NPPA,NPTX1,OPCML,PIK3CD,PACSIN1,PPARA,CNTLN,PTCH1,GAL3ST4,KCTD17,EMID1,ASAP3,SLC1A7,PKNOX2,WDTC1,HECW1,ARC" Drug 2524_UP Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABAT,SRPX,ALK,APAF1,ATP2B2,LDLRAD4,CLCN4,CTNND2,GSDME,ST8SIA3,SEZ6L2,EDN3,COQ7,DMTN,STX2,F5,CACNG2,PTK2B,KIAA1109,C1orf61,FLT1,TMEM8B,MYOZ2,GLS,ATXN2L,KIF5A,NOS1,P2RY1,PCDH9,DUSP26,CCSER2,MARCH1,C12orf49,TCP11L1,PAQR6,NLGN1,EPN2,PKNOX2,PHLDB1,TACC1,TCF7L2,ARHGEF12,CRB1,ZNF34,TMOD1,RPRM,VGF,KCNK12,SLC17A7" Drug 6824_DN Napelline [5008-52-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABHD6,ADRA1D,SEMA6A,CDC14B,ARRB1,NCOA1,ALDH4A1,RIMS2,EDRF1,DNM2,DSCAM,TOM1,FEM1B,IRAK4,ING4,CDKL3,TESK2,KAT8,DISC1,GLYR1,GNG4,PADI2,IGSF1,KCNH2,KCNJ3,LIG4,TM6SF1,KITLG,LYRM9,NRGN,PRKAR1B,MAPK8,ELOVL2,ZSCAN32,PEX5,RAB3A,RAB3IL1,SH3BP2,FBXO11,SLC9A5,SNCA,CDK19,CEP68,STX1A,IQCE,ZNF34,MICAL1,PCBP4,ST7" Drug 3226_DN Zaprinast [37762-06-4]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,BIN1,CDC42BPA,APOC1,CADM3,USP2,LHX2,EPS15L1,CSNK1E,CTNND2,MAML1,MFAP3L,SORBS3,HSD17B14,GLS,GRB10,GRM8,ATXN2L,ELOVL5,HNMT,DHX35,ITPKB,MITF,MMP16,NDUFA5,ODF2,SLC25A23,MAPK7,SAMD9,RAB3A,C1orf54,ZDHHC14,RNASEL,NEK11,RPS6KA2,SBF1,NLGN1,ABLIM3,SMARCD3,RBM34,WDTC1,ZCCHC24,IQSEC2,PLCB1,EXOC7,NSD1,PIK3R5,TRIO,ST7" Drug 7064_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABAT,APBB2,ASPH,BMP7,CDK5R1,SGCE,ARHGAP33,SRSF11,SOCS6,ZFYVE9,NIPBL,SLC4A7,MICAL2,HDAC4,DTNA,RASGRP1,MBNL2,EGR3,DENND4A,F3,EFCAB2,GPD2,NR3C1,INPP5B,KTN1,MATK,MMP16,ZNF862,NF1,NFYA,NUMA1,PIK3R1,LRP12,POLG,PPP5C,SIDT1,ELOVL2,PTK2,WLS,FNDC3A,CEP68,MTCL1,AGTPBP1,RPGRIP1L,TCF12,TRIO,VGF,ZBTB14,NAV2" Drug 3881_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASPHD1,APLP1,PPFIA3,CDK13,ATM,RIPK1,SYNJ2,CBFA2T2,TAOK2,STOML1,PICK1,FEZ1,SIPA1L1,PDE4DIP,GPRASP1,ATN1,EFNA3,ING4,KAT8,ZNF589,USP19,RAB30,GLS,GPR19,PCLO,NR3C1,KCNH2,VWA5A,MDM4,ADAM22,NPTX1,NUMA1,SETD4,OGG1,MAPK8,PTHLH,PEX5,RAD52,DCUN1D2,ASAP3,ZKSCAN3,KDM4C,KIAA1107,ZNF34,SLC44A1,CABIN1,METTL3,TFIP11,WNK1" Drug 5507_DN Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SLC12A5,APC,MARK4,SLC4A4,SCAPER,KYAT1,AP4M1,TAOK2,NECTIN3,MICAL2,PDE4DIP,ZNF337,DMPK,CDON,EFNA3,PLEKHO1,EPB41L1,ERBB2,DLC1,FHL1,GAA,ZNF276,CRCP,MSL3,SPACA9,ITPKB,KCNF1,KCNJ3,LMO2,MITF,MPP2,NF1,MBOAT7,NKAIN1,RAB5B,RAD51D,RAD52,ZCWPW1,BSDC1,FBXW7,FUZ,PREX2,PPP4R3A,LIMCH1,MAPKBP1,KDM4B,ATP11A,ST7,RNF170" Drug 3071_DN Estrone [53-16-7]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ANK3,APOC1,MYRF,HIP1R,SCARB1,HOMER3,CX3CR1,RIMS3,DGKG,DBN1,TRAPPC9,FEM1B,OPTN,RASGRP2,CD320,CGREF1,CSPG5,GABRA4,SEPT9,SRCAP,GRM1,LAMA2,ZNF862,NINJ2,PLTP,MAPK7,BEND5,MYH14,TMEM206,PPM1E,AMBRA1,SNCA,KDM4B,DOP1A,MAPK8IP3,JMJD6,PLCB1,KAZN,ADGRL3,DMXL2,NSD1,ZNF34,THBS4,TMOD1,TPM3,FLRT2,UBE3B,NLRP3,TIGD6" Drug 4363_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SEMA6A,BIN1,APBA2,PPFIA3,APP,EIF4G3,ATP6V0A1,CDK5R1,SCAPER,CAMK2G,KRIT1,ARHGAP33,FOXN3,PLEKHB1,CLCN3,NIPBL,SLC4A7,DNM1,DTNA,ERCC2,NCALD,FGFR1,PRKAG2,NCKAP1,RAB30,STON1,INPP5B,ITPKB,KCNN2,IPO5,LAMP2,MBNL1,LRP12,PPP5C,PRKAR1B,C1orf109,ZDHHC14,RGS12,ZFHX4,SEC14L1,SH3BP2,SLC15A2,ZCCHC24,ZBTB43,PHLDB1,TRIM2,SIK3,HEY2,TPM1" Drug 3999_DN Gramine [87-52-5]; Down 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AMPD3,CDK10,SYNJ2,LARGE1,FOXN3,ARHGAP22,DNAJB5,WHRN,DLG3,ATN1,EDNRA,SORBS3,MRNIP,DMTN,CINP,TRAF3IP2,B4GALNT1,C1QL1,MSL3,PRRC2B,ITPKA,KHK,TAGLN3,PDE4D,EPN1,WDR25,RAB3IL1,RALGDS,KHDRBS2,SBF1,ATXN2,ASAP3,NLGN1,SLC1A7,PPP4R3A,SLC9A5,TSNAXIP1,DDN,MAPK8IP3,TIMP4,CABIN1,TNS1,SSBP2,ZKSCAN5,XRCC4,HPS4,SEMA3B,KCNAB1,NUP214" Drug 7026_DN Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABR,DGKD,APP,CDC14B,NUMB,EIF4G3,CDK5R1,SYNJ2,CAMK2G,REPS2,LHX2,HOMER3,ARMC8,COL4A5,C2CD2,CREM,KIAA0586,GIT2,FBXL5,MAMLD1,EIF5,STX2,EFEMP1,POLR1B,CAMSAP1,TRMO,PDLIM5,ATP2C1,CGREF1,INPP5K,MSL3,GRB10,RNFT2,KCNJ3,MAP4,NRGN,RETREG1,STRN3,PRKAR1B,PTPN13,ZCWPW1,CAMTA2,CEP68,HIRA,UBTF,LMF1,CLDND1,SPHK2,RNF170" Drug 1497_DN "Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADCY6,ALCAM,MRTFA,FAM131A,APP,CDK10,SYNJ2,CAMK2G,MAGI1,ZFYVE9,AKAP12,ABCG1,EDRF1,GIT2,SMG7,ING4,RGS17,EZH1,ZNF589,ZNF276,GNG4,MUM1,INPP5B,ITPKB,MIA2,NF1,SLC11A2,SETD4,SLC25A23,WDR25,NKAIN1,ZCWPW1,MAPK12,FUZ,AMBRA1,FNDC3A,PEX26,SCMH1,BTBD7,SLC20A2,SOX3,ZNF423,PHLDB1,SEMA4A,KIAA0930,TCF7L2,GDPD5,MARCH8,ACTR3B" Drug 959_UP "N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APC,ARRB1,ADAM15,BCL7A,CFLAR,KYAT1,MAGI1,FOXN3,SLC4A8,SIPA1L1,DZIP3,PPP6R2,DBT,SGSM2,DMPK,TRAPPC9,POLR1B,CAMSAP1,SEMA4D,DPYSL4,GPR153,RND1,TXNL4A,GLYR1,NR3C1,ITPKB,VWA5A,NTRK2,NUMA1,PDE4A,ELOVL2,ZDHHC14,PAQR6,FOXRED2,ZFP2,ASAP3,AMBRA1,FBXO11,SMTN,CDK5RAP2,SEMA4A,PSD3,ARHGEF12,SIK3,ZNF34,R3HDM1,DNAJC12,VAV1,EVI5" Drug 7148_UP Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MRTFA,BIN1,ALDH7A1,CFLAR,SCARB1,HOMER3,WHRN,ABI3BP,NRG2,HAPLN1,VCAN,CNTNAP2,LYPD1,SMG7,DTNA,EDNRA,OPTN,AASS,DENND4A,CDKL3,ETV1,SCARA3,FOXG1,TRMO,TRAF3IP2,SEPT9,GLYR1,TDRKH,GUCY1A1,ELOVL5,HSF2,KIF5C,MDFI,MN1,ZNF862,PC,MAPK12,SH3BP2,FUZ,FNDC3A,PPP4R3A,SHANK2,OGDHL,TRIM2,TPM2,TRPS1,WNT7A,EVI5,MPPE1" Drug 6758_DN Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABR,ARHGDIG,ASPH,SPAG9,ARHGEF1,NRXN3,CLCN4,TPP1,QKI,HOMER3,NCOR2,DAPK3,GIT2,CNIH3,MFAP3L,EFNA3,EPHA5,SPEG,ZNF589,FGFR1,ANKFY1,SEPT9,MSL3,GPD2,GUCY1B1,LSS,MIA2,TAGLN3,NASP,NUMA1,PIK3R1,RC3H2,MINDY2,PTPRN2,RIPOR1,RAB3A,RALGDS,FBXW7,SUPT20H,SLC14A1,LIMCH1,ARHGAP26,MAPK8IP3,TRIM2,RPGRIP1L,UGT8,NSD2,EVI5,PHTF2" Drug 3797_DN Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADGRF5,PKP4,SLC4A4,NRP2,CANX,CBS,ARHGAP33,QKI,PICK1,TCEAL2,ETV1,ATP8A1,ZMYND11,USP19,MSL3,GNG3,GPD2,EML4,HSF2,IL6ST,IL12A,ITGA7,JAK2,STRN3,PPP5C,MAPK7,PTHLH,PTPRE,RAD52,ARID4A,RPS20,MAPK12,ZNF821,DOCK10,PREX2,PPP4R3A,ZNF334,TNIK,CDK19,ZBTB43,LHPP,CRTC1,TMPO,TRIO,VGF,WIPF1,KCNAB1,MPPE1,PHTF2" Drug 1608_UP Probucol [23288-49-5]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "RBM10,NDRG2,ADRB2,ALAD,AMT,APBB2,ARNTL,MARK4,SYNJ2,CA12,P2RX6,CD86,PPP1R16B,CX3CR1,DBN1,C2CD2L,DNM1,SIDT2,ENO2,F3,HBS1L,PCSK1N,GNAS,DIDO1,GSTM5,TJAP1,ITGAM,KCNN1,MAP4,MBNL1,PLCB2,SMOX,LRP12,PMS2,PTK2,RFX5,TCP11L1,FAM192A,SLC2A5,SLC6A8,KDM4B,SPP1,ZC3H13,THSD1,MAPK8IP3,SEMA4A,SZT2,RBFOX2,MPPE1" Drug 3924_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC2,ANK1,NRP2,CFAP410,KALRN,SEPT7,STOML1,SULT4A1,LY86,RIMS3,TRAPPC9,FRY,ELN,MTSS1L,ERCC2,IGSF6,SPEG,APC2,EXTL1,REEP2,PTK2B,FHL1,DCTN2,GABRA5,LYVE1,PRUNE2,STON1,GRK4,GRM1,KHK,MDFI,NPPA,NTRK3,PFKFB2,PLP1,POU3F4,C1orf54,FAT4,KLHL11,STUM,CNKSR2,ZSWIM8,CAND2,ARHGAP26,MAPK8IP3,WSCD1,TRH,UCHL1,ADAMTS9" Drug 3308_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,C1QTNF3,DGKD,APOC1,ARRB2,ASPH,ALDH4A1,BTRC,CLGN,ZFYVE9,NCOR1,MICAL2,CSNK1E,FAM169A,DZIP3,TSPAN5,EFNB3,SORBS3,SEMA4D,GPR153,ERAP1,SYT17,DISC1,AHDC1,HNMT,MAP4,GIT1,NF1,PC,NLE1,PPP5C,SIDT1,GON4L,FOXRED2,ANKRD6,PREX2,BTBD7,SLC20A2,ZCCHC24,IQSEC2,TACC1,MCF2L,TCF7L2,ZMYND8,PLPPR2,VGF,ZIC3,EMSY,PCBP4" Drug 1609_UP Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,ACTN2,PKP4,APBB2,CDK10,SYNJ2,RUNX1T1,SEC31B,SPOCK2,SGSM2,SIDT2,EGR3,ANKMY1,FKTN,ZNF589,KIAA1109,OLFM1,BAIAP2,CAP2,OGA,AHDC1,GSTM5,MAP4,NELL2,NOS1,NPPA,NTRK3,P2RX7,PLCD1,RETREG2,PACSIN1,CNNM2,CCDC40,SLC11A1,KBTBD4,ELMO2,DOP1A,SON,WDTC1,ZHX3,EMC1,UHRF1BP1L,ZC3H13,FAM168A,RBFOX2,ELP5,TMPRSS5,REEP1,URM1" Drug 6506_DN Alfadolone acetate [23930-37-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,AMPD2,APC,APLP1,SEMA4G,ALDH4A1,ALDH7A1,KIF1A,GYG2,BTRC,CA12,CDH10,MAGI1,CACNA2D2,PLAA,PDE4DIP,EDRF1,DAPK3,G3BP2,CDON,EGFR,COQ7,ANKMY1,F3,SEMA4D,GAD1,GART,KCNH2,IPO5,MAPT,LYRM9,SLC25A23,LRP12,POLG,RAD51D,RAD52,SH3BP2,AMBRA1,KBTBD4,SPTAN1,SS18,EXOC7,CABIN1,ZMYND8,FAM155A,VLDLR,SYNC,MPPE1,SSPN" Drug 7314_DN Nifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MTUS1,CDC42BPA,APAF1,PPFIA3,APP,SCAPER,PLAA,BAG4,CPS1,NCOR2,GPRASP1,DCAF8,CNIH3,FEM1B,EFNA3,TENM1,RGS17,F3,FCGRT,FECH,PDLIM5,SEPT9,CNTRL,MUM1,ARHGAP19,DIPK1A,KIF2A,ZNF426,PTPRE,FBXW7,SUPT20H,ITSN1,ASAP3,SLC1A3,SMARCD3,LIMCH1,NXT2,ATP11A,IQCE,TMPO,TRIO,TRPC1,ZKSCAN5,HIRA,NDRG4,SPHK2,TFIP11,WNK1,PCBP4" Drug 7344_UP Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABHD6,C1QTNF3,CDK13,SYNJ2,BTRC,CCNT1,ARHGEF2,CACNA2D2,HOMER3,SPOCK3,DSCAM,EGFR,STX2,EFEMP1,HBS1L,DISC1,MALT1,RND1,GNG3,KIF3A,HNMT,IL6ST,KCNJ3,KIF5C,NF1,CNOT4,PTCH1,FAM120C,RFX2,NEK11,DOCK10,FBXO11,EMC1,TROVE2,MAPK8IP3,TTBK2,PLCB1,TCF7L2,CRTC1,SLC44A1,HEY1,PIK3R5,TRPC1,PLPPR2,UPF3A,PRDM2,HPS4,RNF170,SSPN" Drug 7248_DN Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ACLY,CFLAR,SCAPER,CLCN3,COL4A5,TENM4,ARHGAP32,DBT,DLG3,STX2,ETV1,EZH1,TUBB4A,FGFR1,EFCAB2,TRAF3IP2,SESN1,GLS,EML4,NR3C1,RNFT2,MMP16,ZNF862,SERPINI1,PLCD1,MAPK7,SYTL2,TMEM104,PTHLH,PID1,RAP1GAP,MAP6D1,RXRA,SATB1,KBTBD4,BTBD7,ZNF415,TNIK,SRPK2,COLGALT2,SYNE2,VAMP1,ARHGEF9,EXOC7,TCF4,TCF7L2,TRIM2,HEY1,MAP3K12" Drug 4488_UP Amrinone [60719-84-8]; Up 200; 21.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DNAH17,SCAPER,HAP1,LDB2,NEURL1,CHRNB2,EPS15L1,ABCG2,HOMER3,CNTN1,COL9A3,SH2B1,PDE4DIP,SDC3,FRMPD4,ATP8A1,OLFM1,GAB1,GUCY1A2,SHISAL1,ITGA7,KHK,LAMA2,MAOB,KITLG,MOBP,NPR2,OPCML,POU6F1,CEP41,PRKAR1B,MAPK8,PTCH1,ELOVL2,PTPRH,PTPRN2,ZSCAN2,FBXW7,ATP8B4,TCP11L1,SH3BP2,SLCO1A2,SCN3B,EMC1,DMXL2,SZT2,UBE3A,WIPF1,KCNAB1" Drug 5741_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,BIN1,APC,APLP1,CDK13,SLC4A4,BTRC,ASIC3,NMT2,SULT4A1,ENTPD4,ZNF804A,RUSC2,SGSM2,COQ7,CSPG5,GCNT2,ZNF276,GNG3,GNG4,GPD2,HSF2,JAK2,KCNH2,MAPT,ADAM22,MT1M,ZNF862,NEK1,PC,PFKFB2,SERPINI1,RETREG1,PPARA,MAPK7,FAM120C,RGS4,SMARCD3,IFT122,SNCA,EMC1,TROVE2,CEP68,JMJD6,KIAA1107,WWC1,CABIN1,LMF1,EVI5" Drug 7049_UP AH6809; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ARID1A,AP2A2,GAS7,DGKD,APP,PPP4R4,MADD,FUBP1,KALRN,RCBTB2,CTNND2,MFAP3L,G3BP2,EDN1,FAM13A,SUGP2,ING4,VPS26C,TESK2,FOXG1,SORBS1,FYB1,MSL3,GPM6B,STON1,HNMT,SHISAL1,INPP5B,KHK,FSD1,PRPH,PTCH1,GAL3ST4,SCG5,PEX26,SLC9A5,ZNF667,ARHGAP26,PBLD,MAPK8IP3,SEPT8,VPS13A,PLPPR2,VGF,REEP1,NT5M,SMIM8,NUP214,RNF146" Drug 2837_DN Propylthiouracil [51-52-5]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MRTFA,EP400,CDC14B,ST3GAL5,CCNT1,LHX2,RAB26,COL4A5,CREM,NCOR1,PDE4DIP,DZIP3,RABGAP1L,DPH1,ABCC5,ING4,TNK2,NCKAP1,SEPT9,KCNMB4,PRRC2B,CACFD1,RNFT2,MAPT,LYRM9,NRGN,NUCB1,PC,PDE3B,PPP2R5C,PRPH,SMTN,SIRT2,BTBD7,SLC20A2,ZKSCAN3,WDTC1,FNBP1,TROVE2,VPS13A,COBL,IQCE,NSD1,TPM1,PLPPR2,LMF1,MAP3K12,SEMA3B,EPM2A" Drug 5700_DN Felbinac [5728-52-9]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APBB2,APOC1,APP,MADD,ALDH4A1,SLC4A4,BTRC,CA4,KYAT1,SPOCK2,DBT,ARMCX2,JAKMIP2,MFAP3L,NTM,PLEKHO1,ZNF589,HBS1L,GCNT2,GNAS,INPP1,LMO2,LSS,MAP4,TM6SF1,MMP16,LRP12,MAPK8,SNRK,PSMD13,RIPOR1,SAFB,SBF1,FERMT1,ANKRD6,SLC1A7,FAM214B,SLC6A8,ZKSCAN3,WDTC1,POGZ,IQCE,ARHGEF12,TPM1,FAM155A,VAV2,VIPR2,ZNF248,SSPN" Drug 5459_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NME5,LTBP4,BCAS1,CDC14B,STX16,CFLAR,CBFA2T2,FADS2,ABI3BP,ENTPD4,SDC3,EDRF1,DNM2,OPTN,PLEKHO1,ANKMY1,FHL1,GLYR1,RAB30,POLL,GRIK5,ITPKB,KCNJ3,ZNF862,NDUFA5,NF1,NTRK2,LRP12,FAM184A,RGS3,RNASEL,EMID1,SAFB,ZNF430,SLC15A2,LIMCH1,SOX3,TSPYL2,SPART,POGZ,PLCB1,PDLIM2,CABIN1,VGF,VIPR2,SPHK2,SEMA3B,NAV2,EPM2A" Drug 6011_DN Hydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ARHGDIG,PDE8B,ASPH,BTRC,ARHGEF2,ZMYM4,B4GALT6,HOMER3,DBT,CDON,DRD1,RBM12,PLEKHO1,LRRC23,VPS26C,ANKMY1,GABRA2,DISC1,AHDC1,MALT1,RAB30,GRB10,IGSF1,ITPKB,KCNF1,MAP4,SETD4,KCTD15,PRODH,SAMD9,ATG16L1,SH3BP2,EPN2,WDTC1,SPTAN1,IQSEC2,ASTN2,MTCL1,PCDHA6,PCDHA5,CHST8,TMOD1,ZKSCAN5,PLPPR2,VIPR2,XRCC4,SF1,HPS4,MPPE1" Drug 7014_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AK2,APBA2,SCAPER,CACNG1,CBFA2T2,NEURL1,ENTPD4,DAPK3,TOM1,EDNRB,LRRC23,F5,KIAA1109,PRKAG2,SEMA4D,AFF2,FAM49B,TBR1,FYB1,ATXN2L,KCNF1,KCNH2,KCNJ5,KCNN1,MID1,LYRM9,NF1,PDE1C,PRODH,CNNM2,RAB3IL1,ATG16L1,GSTCD,RYR1,SLC20A2,TTC17,SNCA,SPTB,ATP11A,RPGRIP1L,PCDHGA10,TNS2,ZNF34,CABIN1,VIPR2,VLDLR,LAT2,SF1,ST7" Drug 4982_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ALCAM,SRPX,AMT,APP,NCOA1,MPDZ,CFLAR,CACNA1D,SYNGR3,REPS2,PLEKHB1,LHX2,TPP1,AKAP12,PDE4DIP,ARHGEF4,PPP6R2,RCAN1,DTNA,MAMLD1,VPS26C,KAT8,FHL1,PRELID3A,B4GALNT1,DISC1,POLL,NR3C1,IPO5,VWA5A,MAPT,LYRM9,NEK1,PLCD1,PRODH,TMEM104,PLPPR1,PLEKHB2,ZDHHC14,IL17RB,SH3BP2,SMARCC2,NCDN,VPS13A,SEMA4A,ROBO3,TCF7L2,VIPR2,REEP1" Drug 1711_DN Molsidomine [25717-80-0]; Down 200; 16.6uM; HL60; HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "C1QTNF1,ALAD,BEGAIN,APAF1,SEMA4G,CAMK2B,P2RX6,RAB26,SLC4A7,HINFP,RUBCN,DBN1,GSDME,ACOT8,PHF20L1,ING4,IGSF6,EZH1,CINP,GALC,PCSK1N,DIDO1,GRIK5,NOS1,SETD4,PLCD1,PMS2,PTPA,MAPK10,CNNM2,DPF2,MRPS18A,C12orf49,SUPT20H,CCDC88A,EMC1,SPTAN1,CAMTA2,THSD1,SS18,MAPK8IP3,STX1A,TNFRSF1B,TRPM2,TSN,LAMP5,NT5M,LMAN2L,SMIM8" Drug 4181_UP Betulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DPF1,NDRG2,LTBP4,APC,ADGRB3,SYNJ2,AKAP6,CREB5,ARHGEF10,ARHGAP24,DRD1,ATN1,EDN1,EFNB3,ELAVL3,MTSS1L,ALDH1L1,SRCAP,GDF9,GNAL,LPAR4,GRIK5,GUCY1A2,KCNJ3,IPO5,AFDN,MYO7A,ZNF862,NPY,OGG1,P2RY1,PCDH8,GDAP1L1,STRN3,PTPRD,ST6GAL1,BCAN,PKNOX2,NMNAT2,LMO3,FAM189A1,SLC35G2,TMOD1,TRIO,TRPC3,ZNF711,SLC17A7,PHTF2,JPH3" Drug 5923_DN PF-00875133-00 [351322-64-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MTUS1,AMT,SEMA4G,PRX,ARNTL,CDK13,CADM3,CACNA1I,LDLRAD4,NEURL1,TAOK2,QKI,CSF1,CSF1R,DAPK3,DMPK,CDON,ATN1,EN2,FGF12,SORBS1,TPK1,FUT9,ATP8A2,RAB30,STON1,GPR37,PTGDR2,KCNH2,KCNMA1,MSI1,NOVA1,PCDH9,PDE4A,LRP12,MAPK8,RAB3IL1,GAL3ST4,FRMPD1,IZUMO4,EMC1,UNC5B,INKA2,PLCB1,SZT2,TK2,TMPO,KCNK12,DNALI1" Drug 3838_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APBB2,MARK4,ASPH,MTMR2,GYG2,KYAT1,CBFA2T2,RCBTB2,SOCS6,CHM,TAOK2,TPP1,DNAJB5,SH2B1,SDC3,RIMS2,DAPK3,DTNA,EDNRA,MBNL2,EIF4G1,PLEKHA1,ING4,SCML2,KIAA1109,FGF12,GFER,GLYR1,HTATSF1,LSS,NEK1,NFYA,OCRL,SSH1,RETREG1,SNRK,RAB3A,CARF,CCDC25,EPN2,SMARCA4,CDK19,PLCB1,EXOC7,WASHC4,WNK1,SNX27,EPM2A,SSPN" Drug 6219_UP Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASPHD1,AP2A2,AMH,NCOA1,CFLAR,LDLRAD4,CAMK2B,CAMK2G,AKAP12,TBC1D5,C2CD2L,TMCC2,DPH1,DRD1,CNNM1,HSD17B14,IQGAP2,USP19,POLL,BTN2A1,RNFT2,HNMT,KCNH2,KCNJ3,MATK,MBP,MYH7,ZNF862,NF1,SERPINE2,PLCD1,PLEC,PPP5C,MAPK3,GON4L,PTCH1,ELOVL2,RAD52,ZFP30,FERMT1,SNCA,ANKRD12,UBTF,REEP1,SYNC,GDPD5,KCNAB1,ST7,SSPN" Drug 6099_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG2,NME5,ALCAM,KCNAB2,EPB41L5,ARRB1,MARK4,SLC4A4,GYG2,CACNA1I,NEURL1,LHX2,ZFYVE9,FAM189A2,SLC4A8,RCHY1,CSF1R,EDRF1,DAPK3,GIT2,DTNA,EFNA3,PLXNC1,VPS13B,PRELID3A,SEPT9,GLS,POLL,GNAS,RASSF8,IL6ST,JAK2,KIF5C,MPP2,GIT1,ADAM22,NEK1,LRP12,RAD52,WLS,ZNF821,PEX26,SNCA,KIF13A,KDM4C,MAPK8IP3,ELOVL4,CEP68,ARHGEF12" Drug 3122_DN Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADORA3,BIN1,AMT,ATP6V0A1,ADAM15,MTMR3,JAM2,TAOK2,ZFYVE9,CNTN1,IQCK,SIPA1L1,GPRASP1,ZNF337,DGKG,SPOCK2,DNM2,ING4,TNK2,PTK2B,RAB40B,PCLO,GRM1,PFKFB4,PLCL1,PLEC,SLC25A23,PRKCZ,CNNM2,SBF1,SEC14L1,SLC1A7,MYH15,KDM4B,SP2,SPTAN1,CDK19,KANK1,NSFL1C,KAZN,CAMSAP2,TCF7L2,PCDHGA10,ZNF34,PLPPR2,VAV2,BEST1,ZBTB38,PRDM10" Drug 6018_DN Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AGT,PLA2G6,MRTFA,AMH,CDC42BPA,APBB2,DNAH17,CAPRIN2,ATM,ADAM23,CFLAR,GYG2,BTRC,CAMK2G,NEURL1,HOMER3,SIPA1L1,GPRASP1,RIMS3,RABGAP1L,DTNA,STX2,F5,GABRA2,HTATSF1,CACFD1,INPP5B,LIG4,TAGLN3,NF1,NOS1,CNOT4,PDE3B,PDE4A,RETREG1,SAMD9,PTN,RGS3,SOX2,IQSEC2,PHLDB1,ARC,KAZN,ROBO3,MCF2L,PCDHA5,RIMBP2,XRCC4,HPS4" Drug 3192_DN Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADRA1D,PLA2G6,MRTFA,TRMT9B,APOC1,APP,ARRB1,CFAP410,CAMK2G,CRLF1,SOCS6,PLEKHB1,HOMER3,CRY2,NCOR1,FAM169A,CTH,PPP6R2,CTIF,SORBS3,ELAVL3,VPS13B,FGFR1,BAIAP2,FAM49B,TRAF3IP2,CNTRL,NR3C1,HNMT,LMO2,MSI1,NNAT,PRKAR1B,RAD51D,RGS3,RGS10,RGS12,PAQR6,KIF13A,WDTC1,ST5,VAMP1,ATP11A,EXOC7,TRIM2,CRTC1,SLC44A1,THRA,SSPN" Drug 5357_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,PLA2G6,ALK,BCL7A,CFLAR,ST3GAL5,CAMK2G,NCOR2,PDE4DIP,DOCK4,PHYHIP,GIT2,DMTN,F5,DLC1,FGF12,GABRA2,SPACA9,CLASRP,ITPKB,KCND3,KCNF1,MAPT,MIA2,GIT1,SETD4,KCNK10,POLG,ROM1,NEK11,AMBRA1,PPP4R3A,PKNOX2,SMARCC2,RIMS1,ZCCHC24,ZBTB43,NPAS3,CLSTN2,INKA2,CEP68,ARC,EXOC7,TCF7L2,PLPPR2,VIPR2,TFIP11,EVI5,GDPD5" Drug 2629_DN Bepridil hydrochloride [74764-40-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AK2,BIN1,OGT,APBB2,ALDH4A1,MTMR2,CFAP410,KYAT1,SCARB1,ZFYVE9,PPP6R2,DCAF8,RIMS3,MAMLD1,CNNM1,EFNA3,IRAK4,KAT8,FHL1,GPER1,RNFT2,JAK2,KIF2A,MAP4,NF1,SETD4,ODF2,PRKACB,RAD51D,ARID4A,RGS3,RNASEL,NEK11,FBXW7,TCP11L1,FERMT1,SMTN,TMCC1,CLASP2,CEP68,TMPO,TPD52,TPM1,ZMYND8,UBTF,VGF,EMSY,PRDM2,RNF170" Drug 3105_UP Urosiol [128-13-2]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,CNTNAP1,PPP4R4,CADM3,NRP2,THSD7A,REPS2,CHRNA4,TAOK2,CRMP1,AATK,DAPK1,DSCAM,E2F5,EEF1A2,CELSR3,SORBS3,PLEKHA1,LRRC23,KCNMB2,F5,PDLIM5,MYOZ2,ALDH1L1,FERMT2,SCRG1,SCIN,KCNJ5,MAP4,AFDN,MX1,NELL2,NRCAM,OXTR,EPN1,POU3F4,LRRC49,WDR25,MAP6D1,SLC11A1,SNCA,NPAS3,TACR1,TMOD1,TRO,UBE3A,XRCC4,STMN4,PLSCR4" Drug 1977_UP Miconazole [22916-47-8]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ACTN1,BRAP,APP,ARHGEF7,SRSF11,SEC31B,CREM,SOCS5,CTH,PPP6R2,TM9SF4,ZEB2,HP1BP3,KBTBD11,SUGP2,EIF5,ING4,FCGRT,FKTN,UFM1,ATP2C1,SARAF,MPP6,HBS1L,SRCAP,C1QL1,DIDO1,IRAK3,NAP1L1,NFYA,NRGN,GPSM2,PLCD1,FTO,PACSIN1,PRKAB2,SNRK,RAP1GAP,PPP4R3A,SLC11A1,EMC1,UHRF1BP1L,POGZ,SS18,KLHL7,TMPO,R3HDM1,ZNF189,HPS4" Drug 2869_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,ARID1A,CAPRIN2,DDX3Y,BAIAP3,CACNA1A,SIPA1L1,CTIF,DTNA,ELN,FOXG1,SORBS1,PDLIM5,SEPT9,SRCAP,GPM6B,GPER1,ADAMTS13,GRM2,GUCY1A1,HLF,ADAM22,NPTX2,CDK18,PURG,PRODH,PTAFR,S100B,SCN8A,KIF16B,ASAP3,DOCK10,SLC9A5,LIMCH1,ST5,MAPK8IP3,ABCC8,WSCD1,PCDHGA1,PARD3,TRPC1,UCHL1,VLDLR,SYNC,SLC30A3,KCNAB1,ITM2C,MVB12B,NUP214" Drug 7486_DN CP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DPF1,ASIC1,ADORA2A,AK2,APBB2,PPP4R4,ADGRB1,BTRC,CDC42,CLGN,CACNA2D2,SRSF11,DNAJB5,ARHGEF6,CNTFR,ARMC8,BAG4,PDE4DIP,MAML1,CTIF,TMCC2,SLC12A6,ATN1,EGFR,KIAA1109,FGFR1,SEMA4D,PDLIM5,RASSF8,ATXN2L,KCNJ3,KIT,NLE1,PLCD1,MAPK7,MYH14,BCAN,ZNF365,KDM4B,SOX15,SPTAN1,DMXL2,PCDHA5,AHCYL2,TRIO,UCHL1,VIPR2,REEP1,EPM2A" Drug 2518_DN Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG3,NDRG2,AP2A2,BIN1,CFLAR,SYNJ2,C5,CDH10,TPP1,HOMER3,SIPA1L1,RUBCN,ARHGAP32,C2CD2L,SUGP2,RASGRP2,PRKAG2,CAP2,GAA,USP19,GRM8,INPP5B,ARHGAP12,MEF2C,MGAT3,MITF,NNAT,CDIP1,LRRN3,TMEM231,CEP97,GSTCD,PAQR6,FOXRED2,DOCK10,DZIP1,ZKSCAN3,KDM4C,ARHGAP26,TROVE2,SS18,JMJD6,PLCB1,TNS2,FLRT2,VIPR2,XRCC4,SH3GLB2,HPS4" Drug 3176_DN Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABR,AP2A2,LTBP4,APAF1,APC,PPFIA3,MARCH3,CAPRIN2,ALDH4A1,ATM,KYAT1,RAB28,COL4A5,AKAP12,SOCS5,GIT2,KBTBD11,TRAPPC9,CELSR3,SUGP2,EML1,ENO2,ECSIT,BAIAP2,FYN,SEPT9,COPS8,MSL3,PADI2,HNMT,ITPKB,KCNH2,NFYA,SSH1,SLC25A23,FOXRED2,FNDC3A,URGCP,RAB3GAP1,KIF13A,WDTC1,SEMA4A,EXOC7,IQCE,TBL1X,CRTC1,HIRA,LMF1,ZBTB14" Drug 5964_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG2,SEMA6A,TRMT9B,SEMA7A,APC,CFAP410,CACNA1D,CAPN3,LHX2,RAB33A,CLCN4,SLC24A2,CSF1,SPOCK2,JAKMIP2,OPTN,ELN,HSD17B14,EPHB1,ATP8A1,FGFR3,GABRA2,MYOZ2,ALDH1L1,GPM6B,STON1,GPER1,PCLO,GRIK3,NR3C1,NXPH3,CNOT4,NPY,PCSK2,LRP12,RGS10,SEMA6D,ASAP3,SLC11A1,ARHGAP26,THSD1,TAL1,TNS2,TGFBR3,TLR4,LILRA4,RPRM,CA10,PLSCR4" Drug 1776_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; HL60; HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADCY6,AMT,ANK2,APOC1,CDK10,PDE8B,GYG2,CA12,SPAG9,NEURL1,COL9A2,APH1A,TRMO,NSG1,GAP43,RUNDC3A,ADAMTS13,PADI2,NXPH3,TJAP1,KCNA1,NCAM1,NOS1,NPPA,NTRK3,NUCB1,SETD4,PALM,POLG,BCAS3,CCDC40,CRTAC1,TCP11L1,ATXN2,ITSN1,ELMO2,SNAP25,EMC1,UNC5B,FCHO1,TBL1X,KAT6B,FLRT1,ATP6V0E2,ZNF142,REEP1,LAMP5,URM1,NUP214" Drug 7153_UP Pyrithyldione [77-04-3]; Up 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADRA1D,PPFIA3,KYAT1,RAB28,CLCN4,HOMER3,BAG4,HAPLN1,OSBPL3,VCAN,CNTNAP2,SDC3,EDRF1,DAPK3,MFAP3L,SPOCK3,CDON,DMTF1,LRRC23,ANKMY1,TUBB4A,FAM49B,FYN,GAD1,TMEM8B,ACOT7,KCNJ5,KIF5C,MAPT,ZNF862,NPR2,NUMA1,PBX1,RAD51D,SUPT20H,NLGN1,FAM214B,BTBD7,ARFGAP1,SOX2,CLUAP1,ARHGAP26,ARHGEF9,VPS13A,TGFBR3,CABIN1,ZNF711,EVI5,EPM2A" Drug 3080_UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABHD6,MTUS1,AMPH,OGT,FAM131A,PDE8B,CADM3,FUBP1,BTRC,CACNG1,P2RX6,NMT2,TCEAL2,PDE4DIP,RIMS2,USP6NL,KIAA0513,HS3ST2,SGK2,C3orf18,RASGRP2,CDKL3,CAMSAP1,GPM6B,GRM1,GRM7,KLF12,KHK,GIT1,PFKFB4,DUSP26,PNMA3,CNNM2,RIPOR1,ZCWPW1,MYH14,WLS,SH3BGR,NTNG1,CCDC92,PKNOX2,SLC11A1,SORCS3,ZNF423,TBCEL,PSD3,TNS1,CIAPIN1,SSPN" Drug 2362_UP Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "GRAMD1B,OGT,CDC42BPA,ANK3,AQP4,SEMA4G,BAIAP3,CFAP410,CDH2,TAOK2,MICAL2,PDE4DIP,SLITRK5,RIMS3,DBN1,SPOCK3,TRAPPC9,RCAN1,PLXNC1,ELAVL4,RASGRP2,NCALD,PRKAG2,SCARA3,ANKFY1,SIGLEC8,INPP5K,GRIK5,KLF12,ITIH2,KCNN1,LSS,MDM4,MPP2,MSR1,PGAM2,ST8SIA5,RALGDS,FOXRED2,SLC2A5,SNCA,EMC1,ARHGEF9,SYT5,PCDHGA10,TNS2,TMOD1,PARD3,TRPC3" Drug 5576_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "C1QTNF3,LTBP4,APOC1,PPFIA3,ATM,EIF4G3,CAMK2B,MAP7,KRIT1,CBFA2T2,TAOK2,CRY2,SIPA1L1,PPP6R2,RIMS3,EFNA3,STX2,KAT8,ZNF589,BAIAP2,SEMA4D,POLL,GRB10,KCNH2,VWA5A,ZNF862,SETD4,PDE3B,MBOAT7,PRKAR1B,PRPH,RALGDS,ATG16L1,RPS6KA2,EPN2,RBM34,ZHX3,ZBTB43,CLSTN2,DIP2A,PHLDB1,SYT1,TCF7,TRIM2,PSD3,PARD3,PLPPR2,MICAL1,ZNF184" Drug 2718_DN "Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APBB2,CFLAR,CLGN,QKI,CSNK1G3,SLITRK5,TBC1D5,RCAN1,DTNA,PLXNC1,RASGRP2,TESK2,ZNF589,ANKFY1,INPP5K,GLS,LILRA2,ITGAM,KIF2A,SMAD1,NF1,SLC11A2,ENPP2,SLC25A23,STRN3,RC3H2,ZSCAN32,TMEM231,FBXW7,CLIP1,HSPA4L,SLC2A5,ELMO2,SLC20A2,ZNF667,TROVE2,SS18,NXT2,NCDN,STX1A,ARHGEF9,EXOC7,KIAA1107,WWC1,SZT2,KAT6B,TRPS1,HSPBP1,CLDND1" Drug 1013_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APOC1,PPFIA3,ARHGDIG,PDE8B,CAPRIN2,SYNJ2,MTMR3,ARHGEF2,TAOK2,LRIG1,PDE4DIP,ARHGEF4,ST18,DBN1,LYPD1,NTM,RABGAP1L,DYRK1A,VPS13B,ZNF589,KIAA1109,AFF2,GPR153,SEPT9,SRCAP,COPS8,KPNA5,MPP2,NDUFA5,FA2H,PRKAR1B,MAPK8,PEX5,ROM1,TCP11L1,SCN8A,KDM4B,ZHX3,SPART,CLSTN2,THSD1,ATP11A,SMG6,WSCD1,ZNF34,TMOD1,CDK20,TRPC1,VGF" Drug 6354_DN Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,MTUS1,CASK,NUMB,SLC4A4,TAOK2,EPS15L1,CLU,FADS2,QKI,FAM169A,ARHGAP32,GIT2,DNAJC6,LYPD1,DLG3,CNNM1,TNK2,FCGRT,BAIAP2,EFCAB2,TPK1,ATP2C1,PRELID3A,ZMYND11,SESN1,COPS8,GNG4,IDH3A,JAK2,ARHGAP12,SCAMP5,SLC11A2,NUCB1,NLE1,PRPH,SYTL2,CLIP1,CSRNP3,ASAP3,AMBRA1,WDR37,SMARCA4,BEX1,KIAA0930,TNS2,CHST8,NDRG4,MPPE1" Drug 5466_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ADORA1,ALK,GAS7,APLP1,CDK13,MARK4,CFLAR,BAIAP3,CAMK2B,ARHGAP33,CACNA2D2,OSBPL3,ZNF804A,HEYL,EFNB3,ELAVL3,EZH1,OLFM1,CAMSAP1,TPK1,PRELID3A,GAD2,SIGLEC8,ALDH1L1,TDRKH,HRH3,LIG4,LMO2,AFDN,MMP16,ADAM22,NNAT,NPPA,OGG1,SERPINI1,LRP12,SEPT4,RAD52,ZDHHC14,RFX2,MRAS,PPP1R9A,FAIM2,WDTC1,ZCCHC24,CEP68,KIAA1107,RPGRIP1L,EVI5" Drug 6940_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASIC1,ADD2,ALK,ANK3,APBB2,ARHGDIG,CAPRIN2,CFLAR,CAMK2B,CCNT1,SCARB1,CRLF1,PLEKHB1,STOML1,WHRN,SLC4A8,CREM,DUSP9,EDNRA,OPTN,RBM12,C3orf18,APC2,KIAA1109,SEMA4D,HBS1L,INPP5K,POLL,PCLO,ITGA7,MIA2,ADAM22,NCAM1,NF1,GPR85,TMEM231,RAD52,RGS10,TCP11L1,SPTAN1,CLSTN2,ZNF302,TTBK2,VAMP1,ASTN2,IQCE,TK2,ZNF45,NUP214" Drug 7523_DN pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG2,ADORA2A,SPARCL1,ALCAM,BIN1,APAF1,MARCH3,MARK4,GYG2,BAIAP3,FOXN3,CHRNB2,NCOR1,DCAF8,F3,FOXG1,FOXF2,GAB1,HBS1L,SRCAP,COPS8,GNG4,GRB10,MAP4K5,HNMT,MPP2,NNAT,DUSP26,PLTP,PPP3CC,SNRK,WDR25,SYNDIG1,WLS,SLC20A2,EMC1,UNC5B,CLASP2,ST5,CHST5,VAV2,VIPR2,MICAL1,KCNK12,REEP1,EMSY,GDPD5,ITM2C,UBE3B" Drug 7146_DN (R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,SRPX,FAM131A,MADD,BCL2L2,CFLAR,CAMK2G,CLCN3,DZIP3,PARD6A,SUGP2,EGFR,PCOLCE2,F8,SCML2,ST3GAL6,POLR1B,CAMSAP1,SEC23B,EFCAB2,GHR,COPS8,GPD2,DIDO1,HNMT,IFI16,DIPK1A,NF1,SETD4,PDPK1,PIK3R1,PPP3CC,GTDC1,NCBP3,PPP1R9A,TMCC1,PDZD2,TNIK,TSPYL2,ARHGEF9,WWC1,HIRA,UBE3A,LMF1,TFIP11,UPF3A,KAT6A,ADAMTSL3,AAAS" Drug 3409_UP Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SRPX,LTBP4,APBB2,APLP1,ARHGDIG,DNAH17,MARK4,CACNA1I,C5,CAMK2G,PLAA,STOML1,ARMC8,SLC4A7,DZIP3,GREB1,ECE2,INTS1,BRINP1,RCAN1,EFNA3,ELN,FHL1,HBS1L,GCNT2,GLYR1,STON1,ELOVL5,IRF8,KCNH2,KHK,KITLG,MITF,NUMA1,PDE1B,RELN,RAB3A,SHANK2,RBM34,KDM4C,SPTAN1,CLSTN2,PLCB1,CRTC1,PCDHA6,TRIO,SCG2,SMIM8,SSPN" Drug 6814_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "LTBP4,BIN1,ALDH4A1,ADAM23,CFAP410,KALRN,ADGRG1,SOCS6,PLEKHB1,AKAP5,RCHY1,PDE4DIP,RIMS3,ATN1,MBNL2,ELAVL3,DMTN,ATP8A1,TBR1,GAD1,RND1,GNG3,PCLO,GRIK5,GRM1,ITGAM,KCNJ5,KHK,LMO2,MDFI,MMP16,ZNF862,NLE1,TNPO2,MAPK7,RAD52,C1orf54,MYH14,TCP11L1,RPH3A,LIMS2,SNCA,MAPK8IP3,DOCK9,PSD3,TNS2,VIPR2,CLIP2,ITM2C" Drug 367_UP "ICI 182,780; Up 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "RBM10,GAS7,AQP6,ARNTL,CHI3L2,CHRNB2,FADS2,AATK,KIAA0513,RCAN1,ECM2,TSPAN5,EDNRA,SIDT2,OPTN,CALCRL,CDKL3,EYA1,AHDC1,RUNDC3A,NR3C1,GRM8,SLC2A6,ARHGAP19,KCNQ3,KHK,MN1,PCDH9,PLCD1,EPN1,SLC25A23,PMS2,TMEM104,SH3BP2,ZCCHC24,EMC1,TSPYL2,SST,SSTR2,COBL,ATP13A2,RIMBP2,KCTD2,TNS1,MKRN3,LMAN2L,SLC17A7,MPPE1,NUP214" Drug 5637_UP "Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ABR,ASPHD1,NDRG2,GAS7,CDC14B,ARHGDIG,CDK13,BRINP2,DDX3Y,ATP6V0A1,CACNG1,CAMK2B,CDC42,KCNAB3,EPS15L1,ARHGAP24,SPOCK2,CHRDL1,DMPK,SIDT2,PLXNC1,FGF13,FOLR2,GAD1,GRIK1,GRM7,KCND3,KHK,MAOB,TAGLN3,MYCN,PDE4A,PLCD1,TNPO2,MAPK8,SH3BP2,SLC6A8,SLC8A1,SNCA,IZUMO4,INKA2,ABCC8,TBL1X,PDIA2,MICAL1,XRCC4,SLC30A3,EVI5,KCNAB1" Drug 4594_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "KCNAB2,ALDH4A1,SLC4A4,ADGRB2,CACNA1A,CACNB2,ARHGAP33,CLU,DNAJB5,COL9A2,CREB5,CSF1R,RUSC2,DLG3,DMPK,ELAVL3,TNK2,SPEG,OGA,ATXN2L,DIPK1A,KIF2A,MMP16,GIT1,MX1,NPR2,ODF2,CDIP1,POLG,MAPK7,SAMD9,ELOVL2,RAD52,ROM1,RXRA,ZNF821,AMBRA1,DZIP1,LIMS2,SLC14A1,MAPK8IP3,KIAA1107,CHST8,TNS1,UBTF,VGF,VIPR2,CLIP2,EVI5" Drug 2012_DN Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ACADM,ALCAM,OGT,CD38,CDC27,RCBTB2,CLTB,TMEM184B,PREPL,DCAF8,ABI2,RABEPK,EVL,GPR153,MPP6,HBS1L,GAP43,GLYR1,PRRC2B,DIDO1,MAN1B1,JAK2,NAP1L1,OCRL,PCMT1,PDE4A,ENPP2,CDK14,PLCD1,TRHDE,TNPO2,PPP3CB,PTN,RAD51D,RNASEL,MYH14,SGK1,ZKSCAN3,WDTC1,UNC5B,GANAB,NSFL1C,ANKRD12,SIRT1,THBS4,WBP2,UBE3A,GORASP1,PRDM2" Drug 3247_UP Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AMH,APBB2,DGKD,CDC14B,PPP4R4,CDK13,ATP6V0A1,CA12,CAMK2B,ARHGEF1,ARHGAP33,CHRNB2,AKAP7,WHRN,ENTPD4,PPP6R2,DTNA,EGFR,DMTN,FYB1,GAA,RASSF8,PTGDR2,IGSF1,IL6R,MAN2A2,MIA2,MYO7A,NUMA1,PPARA,MINDY2,MAPK8,PRODH,RAB3IL1,ITSN1,SLC6A8,ARFGAP1,DOP1A,KIF21B,ST5,PHLDB1,STX1A,POPDC3,ZMYND8,PLPPR2,VIPR2,SLC30A3,MARCH8,KAT6A" Drug 7185_DN Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SERPINA3,AMPD2,ATP2B1,KIF1A,BCL7A,MTMR2,PTBP2,CREM,ABCG1,ZNF337,INTS1,C2CD2L,DNM2,SUGP2,STX2,GAA,SEPT9,SRCAP,PSRC1,GOLGB1,KCNF1,MAP4,PC,SLC25A23,RAB3IL1,MCMBP,FAM192A,SBF1,ITSN1,AMBRA1,SCMH1,KDM4B,SOX3,ITPRID2,FAM168A,TACC1,ANKRD12,DNMBP,TCF7L2,TNS2,TIAM1,BHLHB9,PARD3,CABIN1,RPRM,PLPPR2,VAV1,VGF,XRCC4" Drug 4408_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "BEGAIN,CDC14B,SEMA4G,CDK13,SGCE,CFAP410,CACNA1A,GPR37L1,CHI3L2,TAOK2,IFFO1,CSF1,CDON,EDN1,FRY,TNK2,PTK2B,NSG1,ERAP1,SIGLEC8,ITGA7,KCNB1,KCND3,KCNMA1,AFDN,MOBP,ZNF862,NF1,NOVA2,NTRK3,OMG,GPR85,PNMA3,TNPO2,CEP41,RGS10,SELL,ZNF821,LIMS2,SLC11A1,SLC12A4,SNCA,SOX15,RGL1,PLCB1,SLC19A3,TUBB1,MVB12B,PAK5" Drug 2160_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG3,NDRG2,ADORA2A,PLA2G6,PPFIA4,MARK4,NCOA1,ATP6V0A1,C5,SCARB1,CDH10,RAB33A,PLAA,TPP1,STOML1,CNTN1,CSNK1E,SLITRK5,DZIP3,CTNND1,SMG7,SV2A,DNM2,E2F5,CELSR3,MRNIP,FLT1,GLS,POLL,LILRA2,ITPKB,AFF1,MYT1,NEFH,SLC25A23,POU6F1,PTPRN2,RAD52,EPN2,SLC11A1,KDM4B,ZCCHC24,CAND2,DDN,PLCB1,PDLIM2,AHCYL2,TMOD1,TPM1" Drug 5595_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ACTN2,ALK,MRTFA,EPB41L5,ARRB1,MARK4,GYG2,CACNA1G,CAMK2G,SLC16A4,CBFA2T2,CDC42,CRLF1,LHX2,STOML1,SH2B1,CSF1,CNTNAP2,MAML1,DAPK3,C2CD2L,EDNRA,SORBS3,DLC1,FGFR1,FOXG1,PRELID3A,GAD2,GAP43,GCNT2,GPER1,ADAMTS13,LMO2,MAP4,MSI1,ADAM22,ATXN7,ASAP3,ABLIM3,SLC22A4,SMARCD3,DOK5,DIP2A,ARC,WSCD1,TCF7L2,PSD3,TMEM121,PLPPR2" Drug 7334_UP Apramycin [37321-09-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ASPHD1,DOC2A,SEMA4G,PDE8B,ALDH4A1,ATP2A2,ATP6V0A1,MTMR3,CDH2,CACNA2D2,FADS2,BAG4,CSF1R,SIPA1L1,ARHGEF4,DSCAM,DTNA,MAMLD1,EDNRB,EFNA3,SUGP2,EZH1,F3,GAB1,HBS1L,DISC1,GNG4,CNTRL,SPACA9,HNMT,MID1,MYCN,NF1,CDK18,PIK3CD,PLPPR1,FAM120C,RIPOR1,KHDRBS2,ZFHX4,ABLIM3,SLC1A7,SHANK2,BTBD7,SMARCD3,KIF13A,RBM34,BEX4,NUP214" Drug 7476_UP Penbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APC,GAS7,PLA2G4C,ALDH4A1,SLC4A4,MTMR3,CAMK2G,STOML1,QKI,ENTPD4,NCOR2,MICAL2,ARMCX2,TMCC2,DMPK,DRP2,RCAN1,SORBS3,GPR153,GLS,GNAS,GNG4,JAK2,LMO2,MATK,MMP16,NF1,NOS1,NOVA2,SLC25A23,PLXNB1,MBOAT7,PPP2R2B,GDPD2,RIPOR1,SH3BP2,SLC1A7,SLC2A5,SHANK2,BTBD7,SNCA,WDTC1,STX1A,WWC1,TRIM2,PIK3R5,FAM155A,ZBTB14,TFIP11" Drug 5800_DN Rauwolscine hydrochloride [6211-32-1]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "C1QTNF3,MARK4,ST3GAL5,SYNJ2,CACNG1,ARHGEF2,DNAJB5,VCAN,PDE4DIP,PPP6R2,ARHGAP24,RUSC2,C2CD2L,TMCC2,DLG3,DPH1,HIPK3,DMTN,CDKL3,ZNF589,FGF1,C1QL1,GNG4,IL11RA,MAPT,MIA2,ZNF862,NF1,NPR2,NTRK2,ODF2,PCDH9,PLXNB1,MINDY2,PPP5C,MAPK7,PTPRH,RAP1GAP,SH3BP2,PREX2,ZNF667,WDTC1,SPTAN1,DDN,COBL,CRTC1,TPM2,SCG2,KCNAB1" Drug 5606_DN Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APBA2,APBB2,GAS7,ATM,EIF4G3,CFLAR,SCAPER,TAOK2,STOML1,AKAP7,CRY2,ATRNL1,PDE4DIP,EDRF1,SMG7,RABGAP1L,EFNA3,MBNL2,STX2,KAT8,FGFR1,SEMA4D,CGREF1,GART,RASSF8,HNMT,KCNH2,KCNJ3,TM6SF1,MIA2,ZNF862,PDE3B,LRP12,FSD1,RAD52,RGS12,SUPT20H,BTBD7,KDM4C,ZBTB43,ELOVL4,PLCB1,TRPC1,FAM155A,XRCC4,SYNC,SLC17A7,SSPN,SENP7" Drug 4726_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,DOC2A,MARK4,ALDH7A1,ADAM23,CA12,CAMK2G,TAOK2,CLCN4,NECTIN3,NCOR2,ARHGEF4,PPP6R2,NOS1AP,KIAA0586,CTIF,BRINP1,MFAP3L,RABGAP1L,DMPK,AASS,SEMA4D,CGREF1,FYB1,GAD1,GFER,GNG4,MUM1,ZNF862,NEUROD1,NF1,SLC11A2,NUMA1,LRP12,PPARA,MAPK7,RIPOR1,SOX2,ZCCHC24,SPTAN1,MAPK8IP3,EXOC7,SMG6,ZEB1,AHCYL2,FAM155A,VIPR2,KCNK12,REEP1" Drug 2970_DN Loracarbef [121961-22-6]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NDRG2,ADD1,AP2A2,BIN1,ASPH,SLC4A4,ATP6V0A1,BACH1,SYNJ2,BTRC,CLGN,SOCS6,CSF1,DZIP3,EDRF1,DGKG,RUSC2,RCAN1,EIF4G2,EIF1,KIAA1109,FGFR1,PDLIM5,ADAM28,GPD2,GPR22,CACFD1,GSN,MAP4K5,ITGA7,NINJ2,SERPINE2,SMOX,SLC25A23,STRN3,MAPK3,RAD52,RGS10,ARHGEF10L,RNASEL,ANKRD6,SLC1A7,SLC2A5,KDM4B,WDTC1,ZEB1,XRCC4,MAP3K12,KCNAB1" Drug 7260_UP Ethamivan [304-84-7]; Up 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "AP2A2,MTUS1,ALAD,APP,STX16,ZFYVE9,STOML1,DNAJB5,QKI,GIT2,DPH1,SGK2,EGFR,LRRC23,ERCC2,ZNF391,F3,BAIAP2,CGREF1,FYN,MAN1B1,ATXN2L,TJAP1,INPP5B,ITPKA,KIF5C,LIG4,MBD1,SLC11A2,MAPK7,MAPK8,FAM120C,WDR37,SLC20A2,SNCA,TMCC1,UNC5B,NXT2,CEP68,VPS13A,SYT1,WWC1,TCF4,HIRA,ZBTB14,EMSY,EPM2A,FAM13C,KAT6A" Drug 7069_DN 0198306-0000 [212631-61-3]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "BIN1,CDC42BPA,SHROOM2,ATP2A2,ADAM15,CNOT8,PLAA,CRY2,PDE4DIP,SLITRK5,EDRF1,ARHGAP32,B3GAT3,PARD6A,SGSM2,ERCC2,FOXG1,SEMA4D,SRCAP,KLF12,KCNJ5,KIF5C,KPNA5,L1CAM,LIG4,NF1,NFYA,PENK,KCTD15,ZNF426,GRAMD1C,BCAS3,RGS3,ARHGEF10L,MCMBP,SUPT20H,DZIP1,BTBD7,SEPT8,ARHGEF9,SZT2,SYNE1,SSBP2,FAM155A,MICAL1,NSD2,ZNF24,HPS4,UBE3B" Drug 3617_UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "ACTN2,GRAMD1B,ADRA1D,TRMT9B,MARK4,DDX3Y,GYG2,CALB2,CLCN4,NRXN2,SPOCK3,ERCC2,SPEG,REEP2,FABP7,PTK2B,DCTN2,ADAM28,GFER,RUNDC3A,PRUNE2,SYNPO,IFI16,ITGA7,KCNJ5,KHK,LAMA2,MBP,MGAT3,CD200,MX1,ZNF862,MYT1,NELL2,NTRK2,PLTP,ELOVL2,KLHDC8A,EMID1,SLC11A1,MAPKBP1,PDZD2,TNIK,TSNAXIP1,ATP10B,SAMSN1,VAMP1,WSCD1,FLRT2" Drug 4186_UP Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "SYN3,AP2A2,DOC2A,APC,GAS7,CDK10,PPP4R4,ZSCAN18,NRP2,CFLAR,SYNJ1,FUBP1,FOXN3,ASIC3,DNAJB5,RAB26,IFFO1,SPOCK2,SGSM2,IRAK4,SPEG,PDLIM5,OGA,HBS1L,GALC,ERAP1,DISC1,GPR162,GRIA4,KLF12,HNMT,KCNB1,MOBP,LYRM9,PGAM2,PRKAR1B,RET,EMID1,KCNIP1,RASA3,NTNG1,SLC15A2,LIMCH1,KIF13A,PDZRN3,TEX15,NSD2,WNK1,PARP6" Drug 2868_DN Phenindione [83-12-5]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "APOC1,CDK10,ATM,MPDZ,CFLAR,SCAPER,BTRC,ASIC3,ENTPD4,ABCG1,DBN1,B3GAT3,TRAPPC9,CELSR3,VPS13B,F3,FER,FGFR1,PDLIM5,GPR153,SRCAP,TXNL4A,BTN2A1,IGSF1,INPP1,TM6SF1,MITF,GIT1,SLC11A2,NRGN,PDE3B,PDPK1,PLCD1,SLC25A23,MINDY2,MAPK8,ATG16L1,RGS3,SLC25A36,GSTCD,CCDC25,ITSN1,SLC22A4,SPTAN1,TCF7,KAT6B,MICAL1,CIAPIN1,NAV2" Drug 1671_DN Meticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "NUMB,BCL7A,CFLAR,HOMER3,SLC4A7,PDE4DIP,B3GAT3,TRAPPC9,DTNA,RBM12,SH3GLB1,SUGP2,CDKL3,EZH1,FER,FAM49B,GALC,SEPT9,MAP4K5,HSD17B1,TJAP1,DIPK1A,MAN2A2,MAP4,MAPT,SLC25A23,RAB3A,RAB5B,ZCWPW1,IL17RB,SH3BP2,ITSN1,KIF16B,PEX26,LHPP,TROVE2,POGZ,ELOVL4,NSFL1C,MTCL1,EXOC7,SIN3B,PSD3,CDK20,TRPC1,HIRA,PLPPR2,EVI5,SEMA3B" Drug 3824_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "DOC2A,AMPD3,SEMA7A,APP,SEMA4G,ATP1A3,NRP2,BMP7,FUBP1,SCAPER,MTMR3,CDH10,STOML1,CRY2,MFAP3L,HIPK3,EFNA3,KAT8,FGFR1,OGA,HBS1L,NEU3,GRIK5,IL12A,ITGA7,ITIH2,LAMA2,MEF2C,NEUROD1,NOS1,OPRL1,PAK3,PCDH9,PFKFB4,STRN3,PKN2,ACSS3,GAL3ST4,FBXW7,NTNG1,SNCA,RBM34,DDN,KAZN,TNS1,NT5M,PHTF2,TIGD6,SENP7" Drug 5814_DN (R)-Propranolol hydrochloride [13071-11-9]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "MADD,ASPH,MPDZ,CAMK2G,CCNT1,LRRFIP1,RAB28,NMT2,CSF1,SIPA1L1,DZIP3,SDC3,PPP6R2,ZFYVE16,RHOBTB1,SMG7,MAMLD1,ACSL4,EFEMP1,CAMSAP1,GSN,DHX35,IL6R,MAP4,MEIS1,ZNF862,NFIX,SSH1,PLCD1,MAPK7,SAMD9,MCMBP,ATXN1,IL17RB,PPP1R9A,PEX26,ZNF430,INTS9,SRPK2,POGZ,SEPT8,SLC35G2,AHCYL2,ATP13A2,ZNF34,BHLHB9,TRPC1,TRIM9,NAV3" Drug 7390_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.67E-04 1.00E+00 4.41E-03 5.01E-02 49 197 "CDC42BPA,APBB2,CASK,MARK4,ALDH4A1,MAP7,ARHGEF1,ARHGEF2,ZFYVE9,CLCN3,HOMER3,RCHY1,BAG4,NECTIN3,DZIP3,KIAA0513,KLHL3,DLG3,CDON,EDNRA,FEM1B,FCF1,SORBS3,ELAVL2,EN2,MFSD10,MAN1B1,SYNPO,INPP5B,KIF2A,SCAMP5,NF1,NUMA1,PFKFB2,SYTL2,ATG16L1,ZNF671,SBF1,SCN8A,SH3BGR,NUBPL,BTBD7,SLC22A4,NXT2,TRIM2,TRPC1,NSD2,MAP3K12,SMIM8" Drug 3887_DN "Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 46 182 "ARID1A,MAP4K3,ZBTB10,SYNJ1,ARHGEF7,ZBED5,NIPBL,PUM1,USP6NL,FBXL5,DYRK1A,E2F5,RASGRP1,WAC,CHST15,SEC24B,TACC2,BRINP3,KIF2A,ARHGAP12,NFE2L2,NFYA,CNOT4,PIK3R1,CCSER2,STRN3,PPM1B,QRICH1,REV3L,SETD5,ATXN7,SCAF8,CHD9,FBXO11,TMCC1,SON,KDM3A,ZC3H4,CAMSAP2,FBXW11,TCF7L2,PUM2,KAT6B,ZMYND8,UBE3A,PRDM2" Drug 446_DN 15d-PGJ2; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "NDRG2,GAS7,LGR5,ARNTL,ATP6V0A1,AP4M1,NIPBL,ABI3BP,HINFP,SDC3,CTH,DLG3,EGFR,SORBS3,BSCL2,EFS,ETV1,KAT8,TXNL4A,RASSF8,HAS2,KCNJ10,N6AMT1,MYL3,CLDN11,PC,GPSM2,PMS2,C19orf57,CNNM2,SPDL1,PTX3,PAQR6,ATXN1,ZNF821,TROVE2,ZFR2,MCF2L,EXOC7,TBL1X,TCF4,UCHL1,DNAJC12,WNT7A,SLC13A3,ZBTB14,ZNF32,AAAS" Drug 5596_DN LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "ASPHD1,AK2,CDC42BPA,PPFIA3,ATP2A2,ATP6V0A1,CAMK2G,LHX2,RAB28,AKAP12,FAM169A,DBN1,C2CD2L,PARD6A,RCAN1,EDNRA,EFNA3,RBM12,EGR3,EPB41L1,VPS26C,EFEMP1,FGFR3,MALT1,SLC2A6,JAK2,KCNF1,IPO5,VWA5A,ELOVL2,RAB3A,SUSD4,ROBO1,WLS,FOXRED2,SGK1,SMTN,EMC1,FCHO1,ELOVL4,KANK1,JMJD6,KAZN,NACC2,REEP1,MVB12B,ST7,SSPN" Drug 2146_UP Trimethylcolchicinic acid [3482-37-9]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "ACTN2,KIDINS220,APAF1,APC,FAM131A,CDC14B,CASK,ARHGDIG,ZBTB10,SLC16A4,CHN1,ABCG2,LRRC23,KIAA1109,HPCAL4,FOXG1,ALDH1L1,GFER,RND1,GPM6B,GPR19,HMGCR,IL6ST,MAP4,SCAMP5,BCO1,ZNF862,SLCO1C1,CNOT4,PFKFB4,SERPINE2,ZCWPW1,GAL3ST4,FOXRED2,MYH15,PALLD,IZUMO4,KDM4C,SPTAN1,ZBTB43,JMJD6,VAMP1,ATP11A,CAMSAP2,PSD3,ATP13A2,TPM3,ZKSCAN5" Drug 970_DN 5230742; Down 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "ADD3,AP2A2,APP,CFLAR,COL4A5,CHD1L,PDE4DIP,DCAF8,DNAJC6,HIPK3,MBNL2,EGR3,KAT8,EFCAB2,CGREF1,GART,ARFIP1,NUDT21,EML4,GPR37,JAK2,KCNJ3,KHK,MBNL1,MDM4,MEIS1,NF1,NRGN,SLC25A23,RETREG2,MBOAT7,PRKAR1B,CEP97,RGS10,FNDC3A,SCMH1,ELMO2,NXT2,NSFL1C,PLCB1,TMPO,KAT6B,RBFOX2,NSD2,ZNF184,TFIP11,MAP3K12,SSPN" Drug 4743_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "GAS7,MADD,CDK13,ATM,CFLAR,ST3GAL5,SYNJ2,GYG2,ARHGAP33,AKAP12,GREB1,DOCK4,DBT,SMG7,DTNA,FCF1,MBNL2,ENO2,STX2,FGFR1,INPP5K,SRCAP,CNTRL,RNFT2,MAP4K5,HNMT,TJAP1,IL6ST,KCNJ3,MIA2,MMP16,PDE3B,LRP12,PMS2,NKAIN1,SLC25A36,ZNF821,COA1,LIMCH1,WDTC1,SS18,SZT2,ZNF34,HIRA,XRCC4,WNK1,MPPE1,SSPN" Drug 1580_UP Furosemide [54-31-9]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "NDRG2,BRAP,C1QTNF3,MAP4K3,APBA2,APP,BACH1,CCNT1,CHRNB2,DCAF8,TRAPPC9,RBM12,FAM13A,GOLGA7,ENO2,EPB41L2,IGSF6,F3,ACSL4,KIAA1109,POMT1,ATP2C1,OGA,GLUL,CLASRP,IFI16,KCNN1,LAMP2,TM6SF1,NFE2L2,PIK3C2A,LRP12,PPP2R5C,SAMD9,PTK2,ARID4A,SLC25A36,DOCK10,AMBRA1,SLC2A5,KBTBD4,KDM3A,EPB41L3,TK2,PARD3,TPD52,TRIM9,LMAN2L" Drug 1174_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "ASIC1,ARID1A,AP2A2,ANK1,ASPH,ATP6V0A1,SYNJ2,BTRC,SLC16A4,ARHGAP33,CNOT8,SULT4A1,CREM,SIPA1L1,PDE4DIP,B3GAT3,SORBS3,EIF1,RASGRP2,DCTN2,GABRA4,GSN,IL11RA,MYCN,PDPK1,CCSER2,ST8SIA5,PPP5C,VPS13C,PTAFR,PTK2,PTN,ZNF493,RGS3,FNDC3A,ZNF415,KAZN,EXOC7,CAMSAP2,SZT2,TEX15,TPD52,HIRA,FLRT2,LMF1,REEP1,GDPD5,PHTF2" Drug 2703_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "KIDINS220,DOC2A,ANK2,APBB2,ARRB1,ASCL1,CAST,HIP1R,CBR1,SLC16A4,AKAP7,RCHY1,CTH,ARHGAP32,ZFYVE16,KIAA0753,SMG7,CNNM1,CELSR3,ELN,RASGRP2,GATM,RUNDC3A,GLS,GRK4,VWA5A,MAP4,NNAT,MINDY2,CEP97,FAM184A,RGS3,RNASEL,RPS6KA2,PPM1E,FRMPD1,IZUMO4,ARHGAP26,TSPYL2,LHPP,ARHGEF9,PDLIM2,TBL1X,PIK3R5,TPM1,UBTF,VLDLR,SENP7" Drug 3252_DN Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "MTUS1,AK2,C1QTNF3,APLP1,PPFIA3,APP,ATM,STX16,CFLAR,BMP7,SYNJ2,FADS2,CSF1,SIPA1L1,GREB1,SMG7,SUGP2,CGREF1,OGA,ZNF44,DISC1,TJAP1,IL6ST,MAP4,MITF,ADAM22,PIK3R1,PMS2,PRKAR1B,ATG16L1,RGS10,RGS12,SLC25A36,GSTCD,SBF1,TRA2B,RASA3,FUZ,DOP1A,POGZ,PRRC2C,TACC1,TBL1X,BHLHB9,KAT6B,ZMYND8,REEP1,WNK1" Drug 5058_DN "Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "APBB2,ADAM15,SRSF11,CHM,SLITRK5,DAPK3,DBT,DLG3,EDIL3,EGFR,STX2,VPS26C,ANKFY1,PDLIM5,ZNF276,SPIN1,GLUL,PCLO,RASSF8,SYNPO,AGFG1,LIG4,MBD1,MBNL1,NEK1,CNOT4,SMIM7,LRP12,PRKAB2,ELOVL2,ATG16L1,RFX5,SBF1,CSRNP3,SEC14L1,PPP1R9A,KDM4B,PEG10,ZBTB43,CEP68,EHBP1,GPR161,TK2,BHLHB9,UGT8,ZNF45,EVI5,KAT6A" Drug 4268_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "MTUS1,PPFIA1,PKP4,ATM,ADAM15,SYNJ2,SPAG9,CDC27,SOCS6,CLCN3,SDC3,DAPK3,DBT,SMG7,SPOCK3,EGFR,MBNL2,FER,SPIN1,PCLO,RASSF8,AGFG1,IL6ST,MAP4,TM6SF1,NFIX,NUMA1,PDE1C,PIK3R1,PLEC,STRN3,RC3H2,PRKAB2,SLC25A36,KIRREL1,SEC14L1,PPP1R9A,TNIK,SPTAN1,PLCB1,PSD3,DICER1,TMPO,SF1,EVI5,KCNAB1,UBE3B,FXR1" Drug 6136_DN Trifluridine [70-00-8]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "GRAMD1B,PKP4,LDLRAD4,SLC16A4,TPP1,CRY2,ZNF337,CTIF,C2CD2L,SMG7,COQ7,ANKFY1,EFCAB2,SEPT9,INPP5K,ZNF276,PSRC1,DIDO1,CIT,ARHGAP19,ATXN2L,ITPKB,MDM4,NINJ2,SLC11A2,PDE4D,PIK3R1,MBOAT7,RIPOR1,RAD52,ZNF493,RNASEL,MAP6D1,FAM214B,MAPKBP1,SNCA,TMCC1,WDTC1,SPATA7,EMC1,KIAA1107,RBFOX2,FLRT2,PLPPR2,XRCC4,ZFP37,ZNF32,ZBTB38" Drug 901_UP 5114445; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 48 192 "APBB2,ATP2B2,KSR1,LDLRAD4,CA4,GPR37L1,SRSF11,PLEKHB1,ARMC8,COL9A3,TRAPPC9,CDON,RASGRP2,MTSS1L,ST3GAL6,KIAA1109,AGAP2,EFCAB2,ERAP1,MSL3,GNAS,GNG4,STON1,CNTRL,MGAT3,ADAM22,NUMA1,GRAMD1C,ZSCAN2,RAB3IL1,RGR,KCTD17,RASA3,ZFP30,SH3BP2,FAM214B,THSD1,SYP,ASTN2,SEMA4A,ROBO3,RIMBP2,TRIO,RUNDC3B,TRO,VAV2,VLDLR,JPH3" Drug 5698_UP Perphenazine [58-39-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 47 187 "NDRG2,FGD2,CDC14B,CFLAR,HAP1,DLGAP1,CHRNB2,SPOCK2,SLC12A6,EGFR,RASGRP2,HPCAL4,TPPP3,GAB1,GAD1,SIGLEC8,RND1,TDRKH,SPACA9,ATXN2L,BCO1,LRP12,PPP2R2B,PTCH1,RASGRF1,RGS12,TCP11L1,SBF1,ZNF821,CPEB3,PKNOX2,BTBD7,ZCCHC24,ZC3H13,AJAP1,PLCB1,POPDC3,TRIM2,TEX15,CDK20,DNAJC12,VLDLR,ZIC3,KCNAB1,PARP11,EPM2A,SSPN" Drug 5204_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.68E-04 1.00E+00 4.41E-03 5.01E-02 47 187 "TRMT9B,AMH,AMT,SLC2A11,CFLAR,HAP1,KRIT1,ZFYVE9,SDC3,TBC1D5,RIMS3,MAGI2,MBNL2,ING4,TNK2,EZH1,REEP2,FAM198B,FHL1,EFCAB2,SRCAP,GLYR1,MSL3,GPER1,CNTRL,AP4S1,MAOB,ADAM22,ZNF862,NELL2,CNOT4,PLEC,PPP2R5C,RAB3IL1,RAD52,RALGDS,ZNF493,PAQR6,WDTC1,DOK5,SS18,RGL1,AHCYL2,XRCC4,MPPE1,MARCH8,SSPN" Drug CID000004837 piperazine Stitch 5.70E-04 1.00E+00 4.42E-03 5.02E-02 23 73 "ABR,ADORA2A,ATP6V1G2,CACNA2D1,CALM1,AP4M1,SLC22A6,SOCS5,MAP4K5,HRH3,HTR2A,HTR5A,KCNK3,NUCB1,P2RX7,SNTG1,AP1AR,SOX10,CLSTN2,SST,ZEB1,ARHGAP9,SLC17A6" Drug CID000002826 pseudococaine Stitch 5.72E-04 1.00E+00 4.43E-03 5.04E-02 119 570 "ABAT,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AMH,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,RGS9,NGB,CAMK2B,CCK,ASIC3,CHRM1,CHRNA4,CHRNB2,JAM2,HOMER3,CNR1,CREM,CRHBP,SLC32A1,CSNK1E,GPSM1,CX3CR1,MYEF2,PARD6A,DLG4,DRD1,EDN1,EDN3,TUBA1B,PPP1R1B,FGF1,ACTL6B,FOXM1,ATP2C1,SALL3,TCERG1,LOXL3,FERMT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IL1RAPL1,KAT7,HAS2,TNFAIP8L3,HNMT,HTR2A,KCNH2,MAOB,MBD1,MMP16,MMP17,MOBP,MYH6,NEFM,NEFH,NOS1,NPY,NPPA,NPTX2,NTRK3,OPRL1,PDYN,PENK,PIK3C2A,PIK3CD,PIK3R1,PPP3CA,PPP3CC,PTHLH,RXRG,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,SCN3B,SYT4,TAC1,TACR1,ZEB1,ACTR6,CABIN1,PIK3R5,TRH,SLC17A7,SLC17A6,NUP214" Drug CID000007360 tetrahydrofurfuryl alcohol Stitch 5.72E-04 1.00E+00 4.44E-03 5.05E-02 12 28 "ADCY2,ADCY5,ADCY6,ADCY8,ALDH4A1,FOLH1,GART,HRH3,PRODH,PTHLH,SPP1,ADHFE1" Drug CID000003925 QX-314 Stitch 5.83E-04 1.00E+00 4.52E-03 5.14E-02 25 82 "ASIC3,CHRM1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM3,KCNJ3,KCNK3,ENPP2,SCN4B,SCN3B,TRPC1" Drug CID000027915 "3,4-dihydroxyphenylglycine" Stitch 6.01E-04 1.00E+00 4.65E-03 5.29E-02 10 21 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,MAPK8,RAB5B,SHANK2" Drug CID000128390 AA-2379 Stitch 6.01E-04 1.00E+00 4.65E-03 5.29E-02 10 21 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000071157 nefiracetam Stitch 6.05E-04 1.00E+00 4.69E-03 5.33E-02 19 56 "ACHE,APLP1,BCHE,CA4,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,CHRM1,CHRNA4,CHRNB2,DMTN,GAD1,GAD2,GRIA1,NCAM1,PRKACB,S100B,SYN2" Drug CID000008924 bis(hexamethylene)triamine Stitch 6.05E-04 1.00E+00 4.69E-03 5.33E-02 19 56 "SERPINA3,DYNLL1,RHBDL1,ZBED1,CREM,MYEF2,ARNT2,HPCA,NCOA7,NFYA,PCMT1,PDYN,PSAT1,PKIA,RFX2,SEPHS1,SLC8A3,HHIP,TPM1" Drug CID010425705 lecithin Stitch 6.19E-04 1.00E+00 4.79E-03 5.45E-02 70 306 "ACLY,ABHD6,PLA2G6,SYT13,PITPNM2,AMPD3,DGKZ,GPAM,DGKD,APOC1,APOC2,PLA2G4C,SPAG9,DGKI,FADS2,HECTD1,CNTN1,PLCXD3,DGKB,DGKG,PITPNC1,CHRDL1,DTNB,EPB41,CD320,F3,PRAM1,AGAP2,AGAP3,ATP6V1H,HRASLS5,ATP8A2,NEU3,GPR162,LOXL3,PLCD4,HMGCR,MAT2A,MBP,MTTP,NUMA1,OLR1,CNTN3,ENPP2,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLP1,MBOAT7,PRKCB,PRKCG,RPE65,ATP8B4,SMPD3,SLC12A4,ADHFE1,PLCB1,SYT1,DDHD1,TPD52L2,PITPNB,PLPPR5,SLC30A4,GDPD5,PLD4,PLSCR4,HRASLS,NETO1" Drug CID000003455 GBR 12909 Stitch 6.20E-04 1.00E+00 4.80E-03 5.46E-02 22 69 "ASIC1,ASIC3,DRD1,PPP1R1B,FOXM1,LOXL3,MCHR1,CIT,HTR2A,MAOB,MBD1,BCO1,PDYN,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,MLST8,TCF12,TRO" Drug CID005310996 ADP beta S Stitch 6.25E-04 1.00E+00 4.84E-03 5.50E-02 28 96 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,CACNA1B,CACNA1E,P2RX6,ENTPD2,PLCXD3,LPAR6,EN2,LPAR4,PLCD4,HNMT,MAT2A,P2RY13,P2RX7,P2RY1,PLCB2,PLCD1,SLC6A7,PLCB1,P2RY12,SHD" Drug CID000005087 Ro-1724 Stitch 6.32E-04 1.00E+00 4.88E-03 5.55E-02 31 110 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRB2,PDE8B,ALDH7A1,CALM1,LRBA,EBF1,ACTL6B,RAPGEF4,CIT,KCNMA1,MATN3,NAP1L2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,ACTR6" Drug CID000643998 GDP-b-S Stitch 6.32E-04 1.00E+00 4.88E-03 5.55E-02 42 163 "ADCY5,ADCY6,ADCY8,ADORA2A,ARHGDIA,CACNA1A,CACNA1B,CACNA2D1,CHRM1,MYL6B,BSCL2,B3GAT1,GALR1,GNAL,GNAO1,GNAS,GNG3,GRM1,GRM2,GRM5,GRM8,KCNJ3,KCNJ4,KCNJ5,KCNMA1,MYL3,P2RY1,PLCB2,PRKCB,PRKCG,MAPK3,RAB3A,ARHGAP26,SST,PLCB1,TAC1,TAC3,TACR1,TBL1X,NTSR2,VIPR2,PLD4" Drug CID000015133 Tr-J Stitch 6.33E-04 1.00E+00 4.88E-03 5.55E-02 13 32 "MTMR2,CANX,QKI,PNKD,GALC,MSTN,GJB1,POLL,MAG,MBP,NBL1,NTRK3,PMP22" Drug CID000547450 NSC153858 Stitch 6.33E-04 1.00E+00 4.88E-03 5.55E-02 13 32 "TUBD1,TUBB3,TUBB4A,FOLH1,TUBA8,TUBA1C,TUBB2B,MAP2,MAPT,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000002317 benextramine Stitch 6.33E-04 1.00E+00 4.88E-03 5.55E-02 13 32 "ADRA1D,ADRA1B,ADRB2,AGT,CACNA2D1,INA,P2RX6,CHRM1,DMPK,HP,HPR,NPY,P2RX7" Drug CID006335948 3-aminopropylphosphinic acid Stitch 6.33E-04 1.00E+00 4.88E-03 5.55E-02 13 32 "CACNA1A,CACNA1B,CACNA1E,CACNA2D1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,SLC6A1,SLC6A11,PEG10" Drug CID000010701 2-nitroimidazole Stitch 6.35E-04 1.00E+00 4.88E-03 5.55E-02 35 129 "ADRA1B,ALDH7A1,DMD,DTNA,DTNB,TUBD1,GMPR2,TUBB3,TUBB4A,FCGR3A,FOXM1,SEMA4D,B4GALNT1,TUBA8,TUBA1C,TUBB2B,L1CAM,MX1,SLC11A2,PDE1B,PPARA,MAPK10,AP1AR,SARS,SLC11A1,ATP11A,KLHL4,MGRN1,SYNE1,ARHGAP9,SIRT1,CRB1,TUBB2A,TUBB1,TUBA1A" Drug CID000024083 magnesium sulfate Stitch 6.37E-04 1.00E+00 4.88E-03 5.55E-02 18 52 "ATP2A2,CACNA2D1,TUBD1,GPHN,TUBB3,TUBB4A,TUBA8,CBX1,STON1,TUBA1C,GRIN2C,GRIN2D,TUBB2B,IPO5,PMP2,TUBB2A,TUBB1,TUBA1A" Drug 2874_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "DPF1,ARID1A,SRPX,ALK,BEGAIN,CDC42BPA,GAS7,PPP4R4,ALDH4A1,CFLAR,CFAP410,CA4,CACNB2,SLC16A4,FHL5,CTIF,TMCC2,DMPK,DNAH9,ATN1,DUSP9,EFNB3,C3orf18,ZNF589,FGF1,PDLIM5,RND1,GLI2,ATF7,PCLO,GRM3,GUCY1B1,ICA1,IRF8,MSR1,TMOD2,SERPINE2,CEP41,RPS6KA2,EMID1,KCNIP1,SH3BP2,SLN,MAPK8IP3,SYT5,TMEM121,ZNF34,CABIN1,EVI5" Drug 1761_DN Syrosingopine [84-36-6]; Down 200; 6uM; HL60; HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "BRAP,ADRB2,PKP4,APAF1,ARNTL,RAB29,PTBP2,KRIT1,LRBA,RCBTB2,SLC4A7,CSF3R,CTH,HDAC4,DPYSL2,SUGP2,ABI2,KIAA1109,SMC2,STAG2,GLS,MAP4K5,IRAK3,ARHGAP19,RBPJ,MEST,NUCB2,RETREG2,MINDY2,PPM1B,CLIP1,NCBP3,ATXN7,DOCK10,ELMO2,SP2,ITPRID2,TTBK2,SUPT5H,PRRC2C,TCF7L2,CLASP1,TK2,R3HDM1,TNS1,METTL3,HIRA,MEAF6,PDSS2" Drug 4367_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABHD6,ADRA1D,AP2A2,MRTFA,BIN1,GYG2,CFAP410,KRIT1,CLGN,SOCS6,AKAP12,ZNF804A,MFAP3L,DMPK,ANKMY1,FECH,FOXG1,RUNDC3A,TDRKH,GPER1,DIDO1,GRIK5,BTN2A1,PADI2,BRINP3,MMP16,NDUFA5,CNOT4,SLC25A23,RAB3IL1,CCDC40,GSTCD,TCP11L1,ITSN1,FBXO11,TMCC1,ZCCHC24,SPTAN1,IQSEC2,CAMTA2,EXOC7,PCDHA6,AP4E1,ZNF106,HEY2,TMOD1,TPD52,PLPPR2,KAT6A" Drug 2791_UP Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "LTBP4,APBA2,PPFIA3,MPDZ,SCAPER,GYG2,CACNA2D1,CBFA2T2,ARHGAP33,B4GALT6,TAOK2,FADS2,AKAP7,TENM4,NOS1AP,DAPK3,DNM1,TRAPPC9,DUSP9,HSD17B14,STX2,ZNF589,CAMSAP1,SORBS1,GPR153,ERAP1,GPER1,VWA5A,MMP16,ADAM22,NF1,PCDH9,CDK18,PLCD1,PTHLH,RAB3A,RGS12,FBXW7,BCAN,PKNOX2,SHANK2,BTBD7,LIMCH1,ZCCHC24,ARC,KAZN,ARHGEF12,CABIN1,TFIP11" Drug 6880_DN BAS 012416453; Down 200; 38uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABHD6,MRTFA,APBB2,PDE8B,MARCH3,MARK4,BAIAP3,SPAG9,CNOT8,FADS2,ENTPD4,LYPD1,SMG7,DMPK,TNK2,LRRC23,DENND4A,ANKMY1,SEMA4D,GPR153,ALDH1L1,SRCAP,GPR37,GRB10,ADAMTS13,CACFD1,TJAP1,LIG4,SCAMP5,RETREG1,MAPK7,MAPK8,RAB3IL1,RASGRF1,ZDHHC14,SLC22A4,UNC5B,ZBTB43,PHLDB1,CHST8,ZNF34,TK2,BHLHB9,HEY2,NR2C2,HIRA,VAV2,VGF,ZNF24" Drug 4798_DN Propantheline bromide [50-34-0]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "LTBP4,DOC2A,APBB2,APOC1,CACNB2,SPAG9,B4GALT6,LHX2,CNTNAP2,HDAC4,SMG7,EDNRA,FEM1B,EFNB3,MRNIP,EPB41L2,CAMSAP1,C1orf61,TRMO,GLS,STON1,MAP4K5,HSF2,DIPK1A,MAP2,MAP4,MAPT,NEK1,PDE3B,PDE4A,PIK3CD,PACSIN1,GON4L,RGS10,ITSN1,SYBU,ELMO2,LIMCH1,SOX2,ZCCHC24,TROVE2,MAPK8IP3,STX1A,THRA,RPRM,VAV2,LMF1,SYNC,SSPN" Drug 4567_DN Cefixime [79350-37-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NME5,BIN1,ASPH,CFLAR,SYNJ2,BTRC,MAP7,ARHGEF1,NMT2,QKI,HOMER3,ENTPD4,TBC1D5,DNAJC6,KIAA0753,FEM1B,FCF1,EN2,LRRC23,ZNF589,PRRC2B,GPM6B,MAP4K5,KLF12,INPP5B,MPP2,GIT1,CNOT4,PCDH9,PDE1C,PLXNB1,RC3H2,RAB5B,RAD51D,RAP1GAP,LIMCH1,TMCC1,ZBTB43,POGZ,CEP68,DIP2A,GSE1,KIAA0930,WIPF1,NSD2,NDRG4,MPPE1,UBE3B,SMIM8" Drug 6129_UP Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NLGN4X,AMPH,CDC42BPA,APOC1,ADGRB1,BMP7,SYNJ2,CFAP410,RUNX1T1,ENTPD2,CHRNA4,TAOK2,DNAJB5,CABP1,SRGAP3,RASGRP2,KAT8,DPYSL4,PDLIM5,TDRKH,KIF3A,TJAP1,KCNN1,LAMA2,MGAT3,MMP16,NRCAM,PDE4A,PDE4D,PLCD1,MORC4,SELL,CNKSR2,SLC1A3,PKNOX2,TMCC1,RBM34,DOP1A,SOX10,ARHGAP26,INKA2,ASTN2,DNAH7,TRPC1,VSNL1,REEP1,SH3GLB2,PRDM2,PARP11" Drug 6786_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "BEGAIN,PDXK,CFLAR,MTMR3,BAIAP3,CA4,TAOK2,CLCN4,FAM149A,RIMS2,RUSC2,PARD6A,DTNA,TNK2,MTSS1L,PDLIM5,B3GAT1,GAA,GLYR1,TDRKH,GPR19,GRM1,HLF,HNMT,IL6R,JAK2,VWA5A,ZNF862,NPY,CDK14,PLEC,SLC25A23,RAB3IL1,RPS6KA2,EMID1,RASA3,SLC15A2,SLCO1A2,SLN,WDTC1,SPTB,STX1A,VPS13A,PSD3,ARHGEF12,TK2,TPM3,VLDLR,SSPN" Drug 4984_DN beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,AMT,ATM,CFLAR,CA12,B4GALT6,TPP1,QKI,SLC4A7,CREM,SIPA1L1,PDE4DIP,FAM169A,C2CD2L,MED12,EDNRA,CELSR3,MRNIP,COQ7,VPS26C,SYT17,GRIK5,SLC2A6,MBD1,GIT1,ADAM22,NF1,LRP12,TMEM104,RAB3A,RAB3IL1,WLS,FOXRED2,SH3BP2,PPP1R9A,PPM1E,FNDC3A,PREX2,SLC6A8,BTBD7,LIMCH1,VPS13A,ROBO3,SLC44A1,TK2,VAV2,WNK1,EVI5,PHTF2" Drug 6040_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASIC1,ARID1A,KIDINS220,KIF1A,CACNA1I,LDLRAD4,KYAT1,USP2,ARHGEF2,SEPT7,CRLF1,CACNA2D2,SRSF11,FOXN3,PLEKHB1,NMT2,GREB1,DAPK3,DNM1,DSCAM,SEZ6L2,PLXNC1,SORBS3,RRAGB,EZH1,F3,FER,FGFR1,FOXG1,SRCAP,TDRKH,CNTRL,ELOVL5,DHX35,LMO2,KITLG,NRGN,SLC25A23,ZDHHC14,TCP11L1,SH3BP2,BTBD7,PHLDB1,STX1A,ATP11A,PCDHA5,DICER1,ZNF34,SSPN" Drug 3051_DN Bemegride [64-65-3]; Down 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ARID1A,BCAR3,APBB2,APC,APOC1,ATP6V0A1,MAP7,CHRNA4,SLC4A7,ABI3BP,SIPA1L1,PDE4DIP,DBT,EXOG,EEF1A2,FEM1B,TUBD1,ATP8A1,FER,PDLIM5,ATP2C1,GAB1,ZMYND11,ERAP1,SEPT9,GLS,GPM6B,LILRA2,ATXN2L,MAP4,MEF2C,AFDN,NCAM1,NINJ2,PPARA,LRRN3,MAPK8,ZSCAN32,ZDHHC14,RET,FOXRED2,GALNT10,SNCA,SOX2,ZHX3,ZEB1,TRPS1,PHTF2,SSPN" Drug 1513_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "CDC42BPA,APBB2,ADAM15,BTRC,CAMK2G,SOCS6,RAB28,FAM189A2,SULT4A1,CHD1L,ARHGEF10,DNAJC6,TMCC2,SUGP2,VPS26C,TESK2,FGFR1,PRELID3A,GART,MALT1,GLYR1,RAB30,GLS,GPR19,GPR37,CACFD1,KCNJ3,MITF,GIT1,NFYA,SLC11A2,CCSER2,FSD1,MAPK8,ROM1,TCP11L1,SBF1,SH3BP2,KIF16B,SLC1A7,ZHX3,EMC1,ARC,TBL1X,CHST8,TPM1,UBTF,SF1,EPM2A" Drug 762_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADD1,SYT13,CDC42BPA,APBB2,NCOA1,NRP2,BAIAP3,LARGE1,CHRNB2,DRP2,VPS13B,EPB41L2,STX2,ZNF589,OLFM1,FGFR1,ZMYND11,USP19,ZNF276,CACFD1,ARHGAP19,ITIH2,L1CAM,VWA5A,GIT1,NEK1,NNAT,NTRK3,PDPK1,PTPA,LRRC49,PTHLH,CCDC40,RAP1GDS1,ZNF671,RXRA,BCAN,SLC20A2,GLT8D1,ERC1,CEP68,VAMP1,EXOC7,DMXL2,SEZ6L,CHST5,ZNF24,MAP3K12,MPPE1" Drug 2774_DN Racecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "MTUS1,APBB2,APP,ARNTL,RIPK1,CBFA2T2,VAX2,COL4A5,PREPL,EDRF1,TBC1D5,MFAP3L,HP1BP3,RABGAP1L,TSPAN5,HIPK3,CNNM1,EPB41L1,SCML2,TESK2,ZNF589,STON1,CNTRL,BTN2A1,KCNH2,MMP16,MPP2,ADAM22,ZNF862,NEK1,NUCB1,RETREG1,PLCD1,WDR25,SH3BP2,SLC6A8,SLC22A4,WDTC1,SOX3,KDM4C,CDK19,THSD1,INKA2,ATP11A,SIK3,UBE2H,VLDLR,LMF1,PHTF2" Drug 1298_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "KIDINS220,APBB2,ARNTL,MARK4,NCOA1,N4BP2L1,CFLAR,ARHGEF7,C5,HOMER3,CHD1L,RNF14,TM9SF4,DBT,ABI2,ERCC2,ERAP1,ARFIP1,HTATSF1,LPAR4,EML4,MUM1,HSF2,ZNF862,SETD4,ZNF426,MINDY2,PTPA,MAPK3,PTK2,ARHGEF10L,CLIP1,ATXN1,ATXN2,AMBRA1,SLC2A5,SIRT2,CCDC88A,BTBD7,KDM4C,DBNDD2,ZBTB43,NXT2,TBL1X,WASHC4,PARD3,TNS1,TRPS1,XRCC4" Drug 3163_UP Glibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADRA1D,DDO,APP,CDC14B,CDK13,ALDH7A1,SYNJ2,CACNA1I,BTRC,NEURL1,FOXN3,LY86,PITPNM3,SNPH,MFAP3L,RUSC2,RCAN1,MBNL2,ACSL4,FGF12,FOXG1,EFCAB2,SIGLEC8,RUNDC3A,RAPGEF1,GRM2,HPSE2,IGF1,KPNA5,TAGLN3,MYL3,ZNF862,NOVA2,P2RX7,PPP5C,PTPRB,SH3GL3,CNKSR2,FAIM2,TBCEL,RPGRIP1L,SZT2,PCDHA5,TLL2,TRIO,XRCC4,ZIC3,NUP214,ADAMTSL3" Drug 2969_DN "(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "BIN1,ANK3,MARK4,SYNJ2,BTRC,CD86,CLGN,ARMC8,CPS1,SH2B1,CRY2,SIPA1L1,EDRF1,SIDT2,EIF4G2,MRNIP,EIF1,LRRC23,FER,FGFR1,PCYOX1,GALC,INPP5K,PCLO,SCAMP5,MX1,NPR2,NRCAM,PDE4A,ENPP2,ZCWPW1,RGS10,MAP6D1,AMBRA1,ANKRD6,SLC1A7,FAM214B,TMCC1,KDM4B,TSPYL2,SEPT8,DNMBP,TCF7,AP4E1,ZKSCAN5,PLPPR2,LAT2,XRCC4,TFIP11" Drug 3282_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABAT,SRPX,SYNJ2,CCNT1,MAGI1,SOCS6,NMT2,COL4A5,SH2B1,CTH,KIAA0586,HP1BP3,NR1D2,RCAN1,DTNA,F8,ANKFY1,ZMYND11,TXNL4A,POLL,GSN,INPP5B,KIF2A,LIG4,MBNL1,CNOT4,NPTX1,NRCAM,PRKACB,PRKAR1B,GON4L,WDR25,ELOVL2,ZSCAN32,TMEM231,RGS10,GSTCD,UEVLD,RCOR3,ZCCHC24,EMC1,THSD1,NXT2,MTCL1,TRIM2,TMPO,CABIN1,ZKSCAN5,UBE2H" Drug 2178_UP Delcorine; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "SLC12A5,APBA2,ASCL1,PDE8B,ZSCAN18,BACH1,LDLRAD4,CFAP410,THSD7A,DGKI,REPS2,CDC42,CDH8,SOCS6,B4GALT6,PDE4DIP,DAPK3,CTIF,DLG4,EPHB1,ZNF276,CACFD1,GRM1,PTGDR2,TJAP1,ITIH2,KCNB1,KHK,MOBP,MPP2,GIT1,SNTG1,PPP2R2B,MAPK10,CCDC40,RGS12,SH3GL3,CXXC4,SNCA,LHPP,IQCE,TCF4,KCTD2,PRMT8,LMF1,SYNC,SLC17A7,KCNAB1,JPH3" Drug 5319_UP Ambroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PPFIA1,KSR1,LHX2,HOMER3,SMARCAL1,PDE4DIP,DZIP3,ZNF337,TBC1D5,GIT2,DTNA,EGFR,F3,KAT8,FGFR1,FHL1,DPYSL4,MPP6,NCKAP1,MSL3,HNMT,JAK2,KCND3,KCNJ3,KIF5C,MAP4,NFYA,OXTR,PC,SLC25A23,PLXNB1,RAB3A,RBBP6,ROM1,TCP11L1,FNDC3A,SOX2,SPTAN1,ZNF302,FCHO1,ANKRD28,SEMA4A,MCF2L,R3HDM1,TRPC1,KCNK12,XRCC4,KCNAB1,MPPE1" Drug 948_DN Y-27632; Down 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "OGT,PKP4,DGKD,APP,ARRB1,ATP6V0A1,PLEKHB1,CLCN3,QKI,ARHGEF6,PARD6A,RABGAP1L,MRNIP,RRAGB,F8,KAT8,PDLIM5,INPP5K,GLYR1,RBPJ,INPP5B,KCNF1,KHK,MAP4,MAPT,MDM4,MPP2,NCAM2,CNOT4,NRGN,NUCB1,SMOX,RETREG2,SIDT1,RAD51D,CHD9,FBXO11,NUBPL,ZNF365,SCMH1,ZKSCAN3,ERC1,MAPK8IP3,CEP68,ANKRD12,AP4E1,NR2C2,KLC2,ZNF142" Drug 2431_UP Melatonin [73-31-4]; Up 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NDRG2,ADCY6,DDX3Y,CDK5R1,CACNA2D1,THSD7A,CHRNB2,ZFYVE9,CLCN4,CNN3,GPRASP1,SPOCK2,DLG3,SEZ6L2,CAMKK2,GAD2,SIGLEC8,RND1,GPM6A,STON1,GRM1,KCNJ5,MAPT,AFF1,NELL2,PDE4D,PURG,TNPO2,PLPPR1,KCTD17,TTLL7,ZFHX4,C12orf49,FERMT1,FNDC3A,ZNF365,SLC1A3,PREX2,SNCA,MAPK8IP3,WWC1,PSD3,AP4E1,PRMT8,TRPC1,ZIC3,MKRN3,REEP1,FZD3" Drug 1701_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "APBB2,ARRB2,MPDZ,BCL2L2,CFLAR,SYNJ2,CCNT1,SLC4A7,ABCG1,DZIP3,GIT2,SIDT2,EZH1,ZNF589,FER,DPYSL4,FAM49B,NR3C1,TJAP1,IL6ST,KCNH2,MAPT,MIA2,MMP16,OGDH,PIK3R1,SNX10,STRN3,POLG,ARHGEF10L,RPS6KA2,KIF16B,EPN2,EFHD1,BTBD7,ERC1,SRPK2,TROVE2,CAMTA2,PHLDB1,TACC1,KIAA0930,CRTC1,AHCYL2,TMOD1,PARD3,HIRA,UBTF,TFIP11" Drug 5622_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "EP400,APC,FAM131A,PPFIA3,PDE8B,SYNJ1,SCAPER,CFAP410,NMT2,ABI3BP,PDE4DIP,HIPK3,STX2,NCALD,RRAGB,KIAA1109,FOXG1,GAB1,GABRA2,HBS1L,MALT1,GLYR1,GLS,NR3C1,ICA1,INPP5B,KCNF1,LMO2,KITLG,NDUFA5,CNOT4,NPTX1,PDE3B,LRP12,PRPH,FAM120C,KIF16B,ASAP3,FNDC3A,COA1,STX1A,PLCB1,ATP11A,CRTC1,CABIN1,ZNF711,SYNC,PHTF2,SENP7" Drug 2083_UP Isoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "DDO,SEMA4G,SLC4A4,MYRF,CCNT1,TPP1,ARMC8,COL9A3,CREB5,DZIP3,SMG7,FEM1B,FCF1,MBNL2,TUBD1,NCALD,TRMO,GPR19,GPR37,PCLO,GRIK2,GUCY1B1,IFI16,SHISAL1,IGFBP1,NFYA,PDE4B,PENK,PLXNB1,MAPK7,KHDRBS2,NUDT11,FBXW7,CLIP1,SLC6A9,TSNAXIP1,IQSEC2,CAMTA2,PHLDB1,SYT1,AHCYL2,DNAH7,THRA,TRPC1,HIRA,ZNF189,MAP3K12,KCNAB1,EPM2A" Drug 1677_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,LTBP4,PPFIA3,CDC14B,MADD,ARNTL,ARRB1,NCOA1,ATM,MTMR9,RIPK1,CFLAR,CCNT1,SCARB1,CNOT8,GIT2,SIDT2,RBM12,MFSD10,TESK2,FECH,CAMKK2,GAA,IPO5,NPR2,OGG1,TMEM104,NEK11,ATXN2,PEX26,SMTN,SMARCC2,CDK5RAP2,RAP1GAP2,MAPK8IP3,ARHGEF9,TACC1,EXOC7,PDLIM2,ARHGEF12,BEX4,CABIN1,ZMYND8,HIRA,UBTF,KLC2,HPS4,SEMA3B,MPPE1" Drug 2381_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NDRG2,ADORA1,SEMA6A,CDC42BPA,APAF1,APP,CDC14B,SPTBN4,ARRB1,ARRB2,GYG2,USP2,NEURL1,CDH8,ARHGAP33,LARGE1,FAM149A,AATK,DCT,CDON,ST8SIA3,SGK2,SORBS3,CDHR1,CDKL3,PIPOX,TRAF3IP2,INPP5K,GATM,PRUNE2,MEF2C,NF1,PPARA,MAPK8,CNNM2,PTAFR,PLPPR1,GAL3ST4,RNASEL,TMEM206,FERMT1,KDM4B,MAPK8IP3,KAZN,WSCD1,ICAM5,SSBP2,CLIP2,LAMP5" Drug 3886_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ACTN2,AMPD3,APC,PLA2G4C,CDK13,ATM,SYNJ2,GYG2,CA12,ARHGAP33,TAOK2,WHRN,NCOR2,CSF1,RIMS2,DNM1,EGFR,SORBS3,ING4,TNK2,HSD17B14,STX2,FGFR1,GPR153,SRCAP,RUNDC3A,MAP2,MMP17,BCO1,NF1,NPTX1,PLCD1,PRKCB,MAPK8,PTCH1,FAM120C,NKAIN1,RASA3,WDTC1,ST5,AJAP1,VPS13A,KIAA1107,TMEM121,SLC44A1,ZKSCAN5,ZNF74,SPHK2,MPPE1" Drug 2313_UP "Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NDRG2,ADCY2,ADORA2A,KIDINS220,PLA2G6,APBA2,GAS7,AQP4,CDC14B,RASL11B,KSR1,CACNA1G,CACNG1,CLGN,GPR37L1,AKAP6,NRG2,HAPLN1,CTIF,RASGRP2,ERBB4,FGFR1,CSDC2,GLS,POLL,GNAL,SOX21,HTR2A,LSS,MAN2A2,ADAM22,BCO1,SERPINE2,ZSCAN2,CXXC4,SOX3,HECW1,ZC3H13,DDN,ARC,ADGRL3,PSD3,ARHGEF12,HIF3A,TNS1,TRO,FAM155A,ST7,ADAMTSL3" Drug 3359_UP Nadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NME5,ASTN1,ST3GAL5,GYG2,LDLRAD4,CAMK2B,RAB33A,LRIG1,PLCH2,RIMS2,RUSC2,ATN1,DTNA,EFNB3,LRRC23,CDKL3,FHL1,FYN,RND1,ADAMTS13,GSN,PTGDR2,HTR2A,ITGAM,KPNA5,MAPT,AFF1,BCO1,NTRK2,KCNK10,ENPP2,GPR85,PIK3CD,PLTP,PEX5,ZSCAN2,RGS3,ZNF821,RASA3,PPP1R9A,ASAP3,SNCA,SOX3,ZC3H13,RBM26,SEZ6L,OSBP2,EMSY,NUP214" Drug 3236_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,APLP1,CADM3,EPS15L1,ZFYVE9,CSF1R,DAPK3,MAGI2,KBTBD11,CDON,DTNA,EGFR,EIF4G2,LRRC23,RASGRP2,SEPT9,GRIK5,GRM8,BTN2A1,ATXN2L,KCNQ3,MGAT3,MMP16,MSI1,MSR1,PC,RETREG1,LRP12,SAMD9,PEX5,RPS6KA2,SGK1,BCAN,NLGN1,FAM214B,PKNOX2,ZCCHC24,IQSEC2,TROVE2,PHLDB1,KIAA0930,TCF7L2,CRTC1,AHCYL2,ZNF34,CABIN1,ZIC3,SCG2,SSPN" Drug 3847_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "MRTFA,BIN1,ARHGDIG,ATM,CFLAR,SYNJ2,GYG2,BAIAP3,CA12,CLU,CNTNAP2,DZIP3,C2CD2L,DUSP9,EDNRA,ING4,ELN,HSD17B14,FGFR1,BAIAP2,AHDC1,GFER,MALT1,MIA2,ADAM22,NTRK2,PLCD1,PRPH,RAB3A,RAB3IL1,RAD52,ENOX1,ZMAT4,EMID1,SEC14L1,SLC1A7,SLC15A2,SNCA,EMC1,UNC5B,SPTAN1,ST5,CRTC1,VIPR2,LMF1,LAT2,KCNK12,ZFP37,ST7" Drug 7174_DN Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "MTUS1,MARCH3,ALDH4A1,EIF4G3,BCL7A,PTBP2,SOCS6,TAOK2,CREM,DCAF8,SPATA2,SMG7,VPS26C,POLR1B,INPP5K,PRRC2B,GPR37,MUM1,RBPJ,IL6ST,MAP4,MIA2,NEK1,NF1,SETD4,SLC25A23,POLG,MAPK3,NKAIN1,FBXW7,PEX26,SLC15A2,SMARCC2,ZHX3,ZSWIM8,ZBTB43,SS18,STXBP1,COBL,ANKRD28,ANKRD12,TCF7L2,CHST8,KCTD2,CABIN1,LMF1,ZNF24,UPF3A,EPM2A" Drug 6042_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,ADCY2,BRAP,ADRA1D,KIDINS220,PLA2G6,FAM131A,ATP2A2,KSR1,USP2,FOXN3,WHRN,CRY2,SDC3,RASSF2,JAKMIP2,EDNRA,CELSR3,MBNL2,PLXNC1,CAMSAP1,PDLIM5,GABRA2,B4GALNT1,RAB30,IL6R,KCNF1,KCNH2,KPNA5,MAP4,MMP16,MSI1,NDUFA5,NNAT,CCDC25,RPS6KA2,SEC14L1,SH3BP2,ASAP3,SLC15A2,PHLDB1,VAMP1,PLCB1,EXOC7,TNS1,WIPF1,SYNC,EVI5,NUP214" Drug 6603_DN Reserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PPFIA3,CACNA1A,CBFA2T2,SCARB1,ARHGEF2,TPP1,HOMER3,MFAP3L,EXOG,DMPK,CDON,TOM1,EFNA3,FAM13A,MBNL2,EN2,PLEKHO1,PDLIM5,FYN,GLS,GPM6B,MAN1B1,KPNA5,IPO5,MAPT,MDM4,LYRM9,PC,PLEC,MAPK7,GRAMD1C,RAD52,RAP1GAP,FUZ,SLC4A3,SLC6A8,SMARCA4,EMC1,ZBTB43,DDN,WWC1,SMG6,RPGRIP1L,SZT2,PARD3,CABIN1,NDRG4,FTSJ1,NT5M" Drug 6194_DN genistein; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PLA2G6,AMT,GAS7,APOC1,APP,ZSCAN18,ATP2A2,ADAM23,BMP7,SYNJ2,SCAPER,LDLRAD4,STOML1,FADS2,HOMER3,TBC1D5,TRAPPC9,DTNA,COQ7,RASGRP2,CDKL3,ANKMY1,DLC1,FHL1,DIDO1,ITGAM,KCNN2,NLE1,PLCB2,PPP3CC,ZNF493,RET,PLPPR3,FOXRED2,SLC1A3,SLC2A5,ZNF667,SPP1,KDM4C,KIF1B,DDN,KAZN,CUX2,KCTD2,TNS1,CDK20,CADM1,HPS4,UBE3B" Drug 3072_DN Rolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADORA2A,ADRA1D,PLA2G6,FAM135A,PKP4,APC,MARK4,ADAM23,CFLAR,BMP7,SYNJ2,MYRF,BTRC,HIP1R,SCARB1,FOXN3,CLCN4,ZNF337,CTIF,KIAA0753,DTNA,EIF4G2,TNK2,RASGRP2,CD320,ZNF589,CAMKK2,GABRA4,SEPT9,PCLO,GRM1,ACOT7,MSRA,ZNF862,NRCAM,NUMA1,PLPPR1,BEND5,AMBRA1,SLC1A7,ZNF667,WDTC1,KAZN,EXOC7,ADGRL3,TPM3,PLPPR2,NPDC1,PHTF2" Drug 3305_UP Cisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABHD6,ARID1A,KIAA1324,SPARCL1,CDC42BPA,APBA2,CACNA1A,RHBDL1,RCBTB2,FOXN3,QKI,HOMER3,CSF1R,CYBB,RIMS3,DAPK3,CTIF,JAKMIP2,MTSS1L,SEPT9,GNG3,GRIK5,NR3C1,GRM1,GRM8,SOX21,HRH3,ATXN2L,LSS,MBP,MDM4,PLCD1,PLTP,SLC9A5,WDTC1,TSNAXIP1,ZNF423,MAPK8IP3,ARC,KIAA1107,WSCD1,SZT2,DOCK9,HEY2,RUNDC3B,KCNK12,SPHK2,KCNAB1,KAT6A" Drug 6468_DN Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "SEMA6A,LTBP4,MARK4,CAPRIN2,B4GALT6,NMT2,NECTIN3,SH2B1,GREB1,GIT2,HP1BP3,RABGAP1L,DLG3,DTNA,TOM1,EDNRA,SIDT2,EFNB3,CDKL3,F3,SESN1,GLS,GPER1,HSF2,KCNJ3,MAPT,ZNF862,NEK1,NF1,SETD4,PIK3CD,ZSCAN32,TMEM231,RAB3IL1,ZNF821,BCAN,LIMCH1,TROVE2,MAPK8IP3,TTBK2,TBL1X,TMOD1,RBFOX2,SSBP2,DNAJC12,VAV1,MICAL1,XRCC4,SSPN" Drug 6144_DN Piretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASIC1,MTUS1,APC,ARHGEF7,SGCE,CDC42,RAB33A,ZFYVE9,CREM,CRMP1,ARHGEF10,CTNND1,CELSR3,MRNIP,ZNF589,FHL1,SEPT9,ZNF276,POLL,SPACA9,ITIH2,NDUFA5,PDE4B,SERPINE2,PIK3R1,CCSER2,NLE1,MAPK8,RIPOR1,RAD52,TCP11L1,MAP6D1,MRAS,FAM102A,SPATA7,SS18,SYN2,EXOC7,ADGRL3,TNS2,CHST8,TGFBR3,THBS4,HIRA,VIPR2,LMF1,CLIP2,KCNAB1,MARCH8" Drug 6142_UP Dorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NR0B1,C1QTNF3,BCAR3,APBB2,B3GALT2,HIP1R,FAM149A,ATN1,DSCAM,SEZ6L2,ERBB2,TUBB4A,AGAP2,AFF2,KHDRBS3,GPR75,GNAL,GPD1,GRIK2,GRM7,KIF5C,MATN2,MGAT3,MYT1,NCAM1,NOS1,MASP1,PLPPR1,PTHLH,NTNG1,CNKSR2,NLGN1,ZNF365,DOP1A,ZHX3,SP4,SPTAN1,TROVE2,INKA2,WWC1,WSCD1,AMACR,TMPRSS5,UGT8,BEST1,SPHK2,SLC17A7,KCNAB1,SSPN" Drug 6473_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADORA2A,AP2A2,PLA2G6,BIN1,CDC42BPA,APC,EPB41L5,FAM131A,CDC14B,CDK10,ADAM15,CACNA1I,LDLRAD4,LHX2,SH2B1,CNTNAP2,NOS1AP,ZNF337,RABGAP1L,DSCAM,DTNA,EDNRA,EFNA3,PLXNC1,COQ7,OGA,GNG4,DIDO1,CACFD1,IDH3A,KCNF1,KCNH2,MMP16,NELL2,NF1,P2RY1,MINDY2,PTN,ZCWPW1,FBXW7,SMTN,DOK5,SEMA4A,TRIM2,RBFOX2,ZMYND8,PLPPR2,HPS4,SEMA3B" Drug 6460_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ACTN2,ADORA1,NR0B1,C1QTNF1,ALCAM,KSR1,SCAPER,SGCE,CBFA2T2,ADGRG1,ZFYVE9,CSF1,RIMS2,RIMS3,F5,FOXG1,AGAP2,KHDRBS3,ERAP1,SRCAP,MSTN,GPR75,GPM6B,IL6R,ITIH2,KCND3,KCNJ4,KCNJ5,KCNMA1,MARK1,MBD1,ADAM22,NF1,NKAIN1,RAD51D,ENOX1,ZNF493,RGS12,EMID1,KANSL3,SLC11A1,KIF21B,TSNAXIP1,AJAP1,PLCB1,POPDC3,TRIM2,KCNAB1,JPH3" Drug 5406_UP Nizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PLA2G6,MRTFA,BIN1,GAS7,APOC1,ASPH,ADGRB3,CDC42,KCNAB3,CDH10,RGS6,DTNA,ANKMY1,EXTL1,EYA1,KIAA1109,FHL1,GABRG2,GALC,SRCAP,GNAL,PRUNE2,GPM6A,KPNA5,MID1,NFYA,CNOT4,NTRK2,CDK18,TMOD2,PIK3CD,PLCD1,PTAFR,PTHLH,PTN,RAD52,SYNDIG1,ASAP3,FBXO11,SMARCD3,ZCCHC24,TSNAXIP1,ATP10B,SYN2,DOCK9,UCHL1,ZIC3,ADAMTS9,KCNAB1" Drug 6806_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AMPH,BIN1,APBA2,CDK13,MARK4,CHRD,ALDH7A1,AZGP1,CACNA1I,KALRN,MTMR7,CDH18,CLCN4,COL9A3,AATK,CSF1,PDE4DIP,RUSC2,TMCC2,ATN1,EFNB3,FHL1,GAD1,PCLO,GUCY1A1,HAS2,ICA1,IRF8,MAN2A2,ADAM22,TAGLN3,ZNF862,NF1,SAMD9,PTCH1,RIPOR1,BEND5,CRTAC1,ZMAT4,RAVER2,PKNOX2,SLC11A1,KDM4B,KIF21B,ARHGAP26,MAPK8IP3,DOCK9,TNS2,LAT2" Drug 7266_UP THIP Hydrochloride; Up 200; 22.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "RALGAPA1,ASIC1,ADCY6,SHROOM2,CDK5R1,FOXN3,RAB28,STOML1,DZIP3,LYPD1,EIF4G2,RGS17,KCNMB2,F3,FOXG1,GAD2,TMEM8B,SRCAP,CNTRL,INPP5B,JAK2,KCNN1,KIF5C,VWA5A,NFYA,NOVA2,SLC11A2,POLG,WDR25,ZSCAN32,PTPRE,RAB3A,RAB3IL1,RGS4,MYH14,ZFP2,FAM214B,SMARCD3,MYH15,SOX10,SYT1,KIAA1107,FBXW11,TRIM2,TK2,CABIN1,SSBP2,ZNF189,EPM2A" Drug 4947_UP Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "FAM131A,BRINP2,ALDH7A1,CACNA1I,MYRF,BAIAP3,CACNG1,CAMK2B,CBFA2T2,CLCN4,NRXN2,WHRN,CRMP1,MICAL2,EDRF1,RIMS3,ST8SIA3,EGFR,TNK2,NRN1,KIAA1109,AFF2,FYB1,GNAS,KCNH2,MGAT3,NNAT,CLDN11,CDK14,CAMKV,MTRF1L,MAPK7,PTPRB,RAD52,RGS12,CCDC25,TCP11L1,KCNIP1,LIMCH1,WDTC1,ZNF423,VAMP1,PLCB1,SYP,POPDC3,SYNE1,CHST5,TRIO,VAV2" Drug 3757_DN Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASIC1,ADGRF5,AMPD3,ATP2A2,BMP7,SYNJ2,AP4M1,CHM,NRXN3,CLCN4,RAB26,SLC4A8,NRG2,CTNND2,HDAC9,LYPD1,SGK2,FGFR1,ZMYND11,GNAS,CNTRL,SHISAL1,IL11RA,INPP5B,VWA5A,MAPT,CNOT4,PRKAR1B,SAMD9,PTHLH,RAB3IL1,RAD51D,RAD52,RGS4,RGS7,RBM34,ATP10B,TBCEL,TCF4,ZEB1,DNAH7,GPR161,TIAM1,TNS1,TRIO,HIRA,LAT2,SCG2,TIGD6" Drug 6474_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASIC1,AK2,MRTFA,TRMT9B,BIN1,ANK3,APP,CFLAR,CACNA1I,CCNT1,B4GALT6,LHX2,PLAA,SLC4A8,ABI3BP,ENTPD4,DAPK3,MFAP3L,EDNRA,EGFR,SORBS3,EZH1,FHL1,CINP,OGA,HSD17B1,MAP4,NEK1,SLC11A2,PLEC,PEX5,RAB3IL1,ZDHHC14,RGS10,FERMT1,BCAN,NLGN1,WDTC1,TROVE2,MAPK8IP3,ARC,TCF7L2,THRA,FAM155A,PLPPR2,URM1,KAT6A,TIGD6,SSPN" Drug 6302_UP Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PPFIA3,CACNG1,CALB2,RUNX1T1,SCARB1,SYNGR3,CHRNB2,TAOK2,RAB33A,VCAN,PDE4DIP,MAML1,SPOCK3,CELSR3,ELN,COQ7,EZH1,ABCA8,ZNF589,KIAA1109,FYN,TRAF3IP2,SIGLEC8,INPP5K,ZNF276,KLF12,IL6ST,INPP5B,SMAD1,MGAT3,MT1M,NFYA,PBX1,NDUFS7,PTCH1,RAB5B,RGS12,MYH14,SH3BP2,EPN2,CCDC88A,SLC9A5,KANK1,EXOC7,ZEB1,ARHGEF12,VGF,ZNF225,NT5M" Drug 5746_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADORA1,NME5,APBB2,AQP4,PRX,ASTN1,SCAPER,CA12,CACNG1,KCNAB3,SH2B1,DTNB,EDNRB,PLXNC1,ELN,FABP7,FOXG1,GPR19,LPAR4,KLF12,KCNA4,KCND3,NDUFA5,NEFM,NF1,NPR2,TREM2,SNTG1,GPR85,RALGDS,C1orf54,RGS4,STUM,PKNOX2,FAIM2,TMCC1,DOP1A,KIF21B,ZSWIM8,HECW1,LHPP,SYT5,CRB1,THRA,TRPC1,RPRM,LAT2,ZIC3,KCNAB1" Drug 2030_UP Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "RALGAPA1,ACTN1,NDRG2,APBB2,SHTN1,CDK10,CADM3,SYNJ2,MTMR3,LDLRAD4,SLC25A14,CAPN3,CD86,SLIT2,RAB33A,DCAF8,EFNB3,BSCL2,F3,KAT8,OLFM1,CAMSAP1,SRCAP,GDF9,USP19,LILRA2,HNMT,ICA1,TJAP1,KIF5A,LSS,NINJ2,PRKCZ,RAB3IL1,TRIM68,TCP11L1,GALNT10,SLC15A2,ELMO2,IFT122,TMCC1,DOK5,ZBTB43,TSPYL2,SEMA4A,CLASP1,PHF24,KAT6B,ACTR3B" Drug 2120_DN Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AP2A2,PPFIA1,APP,ARRB2,ZBTB10,MPDZ,BCL2L2,PTBP2,FOXN3,HOMER3,FEZ2,PDE4DIP,SGSM2,TRAPPC9,EDN1,RBM12,YAF2,F3,EFEMP1,ARHGAP19,LIG4,NAP1L3,SETD4,PDCD2,PTPA,PTHLH,PTPN13,RIPOR1,RAB3A,RPS6KA2,ATXN1,SCP2,IL17RB,SUPT20H,SH3BGR,ITSN1,SS18,ARHGEF9,EXOC7,PDLIM2,TCF4,METTL3,SMUG1,LMF1,WIPF1,HPS4,PLSCR4,PDSS2,AAAS" Drug 5861_UP Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "C1QTNF1,MRTFA,DOC2A,APC,CDK13,RGS9,MAP7,CLDN10,CRLF1,DNAJB5,CNTN1,AKAP6,CSF1R,PDE4DIP,EDIL3,EFNB3,TENM1,VPS26C,CACNG3,CORO2B,FCGRT,SORBS1,DISC1,GFRA2,MSL3,GNG3,PRUNE2,LPAR4,SCIN,KCNF1,MDFI,NF1,NNAT,PPP1R1A,PRKAR1B,MAPK10,PTPRN2,SLC4A3,SLN,KIF13A,DOK5,ARHGAP26,ASTN2,TACR1,FAM189A1,CRTC1,WIPF1,LAT2,SLC17A7" Drug 1553_UP Oxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ACLY,APBB2,ARNTL,ASPH,N4BP2L1,BARD1,CCNT1,RIMS2,CX3CR1,MED12,FEM1B,SIDT2,APH1A,PRKAG2,PDLIM5,MPP6,KIF5A,KTN1,MYT1,NEUROD2,NPPA,NTRK3,SETD4,PDE3B,SMIM7,PPP2R5C,CNNM2,PTK2,PTX3,ARID4A,ARHGEF10L,RNASE1,SH3BP2,SLC6A8,KBTBD4,KDM4B,DOP1A,ZSWIM8,TSPYL2,SYN2,MCF2L,MGRN1,TCF7L2,SMUG1,PRDM2,FIP1L1,CAMK1G,NUP214,AAAS" Drug 6992_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADRA1D,SEMA6A,AMPD3,BIN1,SHROOM2,PDE8B,NCOA1,CFLAR,OSGIN2,BTRC,IFFO1,CRY2,NCOR2,CSF1,PDE4DIP,CTH,RIMS2,EDRF1,GPRASP1,KIAA0586,GIT2,SGSM2,TMCC2,MED12,CDON,EIF5,ENO2,MTSS1L,KAT8,GPR153,OGA,DISC1,COPS8,GLS,TJAP1,KIF5C,MAP4,EPN1,PTN,CCDC40,RAD52,SMARCD3,RBM34,ARHGAP26,SPTAN1,ACSBG1,BCL2L13,LMF1,ZNF74" Drug 6426_DN 0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "MTUS1,APLP1,PPFIA3,APP,SLC4A4,SYNJ2,CBFA2T2,CNOT8,RAB26,PHF14,LYPD1,SMG7,SPOCK3,F8,DLC1,BAIAP2,DISC1,GBX2,SRCAP,POLL,GPM6A,TJAP1,KIFC3,TAGLN3,NEK1,NF1,NLE1,BCAS3,FAM184A,ZDHHC14,TTLL7,SEC61A2,NEK11,RXRA,SCG5,ITSN1,SH3GL2,FBXO11,ZNF415,WDTC1,TNIK,BEX1,TROVE2,ST5,TK2,BEX4,WNT7A,XRCC4,DPF3" Drug 4697_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "KDM5D,NDRG2,ADD2,NME5,LTBP4,SEMA4G,BRINP2,SLC4A4,CACNB2,QKI,RCHY1,CREM,ARMCX2,ELMO1,DPH1,ING4,ANKFY1,GALC,RUNDC3A,GLYR1,GRB10,GSN,ELOVL5,TJAP1,KCNJ3,KCNMA1,LIG4,VWA5A,AFDN,MMP17,PLCD1,LRP12,C1orf54,ROBO1,TMEM206,ZNF821,SLA,FAM214B,EMC1,KDM4C,EPB41L3,NCDN,AJAP1,ROBO3,KAT6B,OSBP2,VGF,MICAL1,ZIC3" Drug 5503_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "SYN3,MRTFA,BIN1,APP,ASPH,RASL11B,ATP1A3,SLC4A4,ALDH7A1,CDK5R1,SGCE,CACNA1I,B4GALT6,CNTNAP2,DZIP3,RIMS2,ING4,EPB41L2,ZNF589,FHL1,CNTRL,GRB10,NR3C1,KCNH2,KIF5A,VWA5A,MMP16,NFYA,RAD52,C1orf54,NEK11,RPS6KA2,PEX26,SMTN,KANSL3,COA1,SMARCA4,TMCC1,ATP10B,TROVE2,ST5,PLCB1,ASTN2,ANKRD12,CRTC1,TGFBR3,HEY2,XRCC4,EVI5" Drug 1204_UP "aspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADRA1D,ADGRF5,ALAD,GAS7,BCAS1,MARK4,STX16,MPDZ,CHN2,CLCN4,TPP1,DNAJB5,AKAP7,PARD6A,SPOCK3,HIPK3,EIF5,MRNIP,FGFR1,AFF2,CSDC2,C1QL1,ICA1,SCIN,MAP4,NF1,CNOT4,PDGFRA,PIK3CD,POLG,WDR25,CNTLN,PTN,TMEM231,RAB3IL1,GAL3ST4,ATXN2,PEX26,SLC6A9,BTBD7,SLC20A2,KDM4C,EXOC7,ATP13A2,WNT7A,SPHK2,SCG2,HPS4,AAAS" Drug 4090_DN Myricetin [529-44-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADCY6,AP2A2,NME5,ST3GAL5,SYNJ2,LARGE1,NCOR2,TBC1D5,PLPPR4,CHRDL1,DYNC1I1,EDN1,FAM13A,EGFR,IRAK4,LRRC23,STX2,ETV1,IQCG,TACC2,C1QL1,TDRKH,DIDO1,INPP5B,KHK,KIFC3,NFYA,NPR2,PAK3,PBX1,PLCD1,GRAMD1C,ZSCAN32,ZSCAN2,ATG16L1,FBXW7,CSRNP3,ATXN7,ZFP30,DZIP1,ARHGEF40,SLN,LIMCH1,TROVE2,CRTC1,GPR161,TK2,EMSY,SEMA3B" Drug 2651_DN Suloctidil [54063-56-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ALDH4A1,CFAP410,CAMK2B,KYAT1,SCARB1,PLEKHB1,NMT2,ARMC8,SLC4A8,GREB1,PARD6A,CNNM1,EFNB3,SORBS3,PCOLCE2,AGAP2,CAMKK2,CSPG5,GPR19,KCNJ3,MAPT,GIT1,NASP,OGG1,RETREG1,KCTD15,RIPOR1,NEK11,LGR4,WLS,FUZ,PEX26,SMTN,SLC15A2,SOX3,SEPT8,CEP68,PHLDB1,ARHGEF9,TACC1,EXOC7,TCF7,ATP13A2,TMOD1,CDK20,LMF1,MPPE1,MVB12B,SSPN" Drug 4252_DN Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PDE8B,ATP1A3,ADGRB2,BAIAP3,HOMER3,COL9A2,RCHY1,EDRF1,SGSM2,ATN1,DTNA,PLXNC1,IRAK4,LRRC23,IQCG,ALDH1L1,RUNDC3A,GPR19,GRIK2,GRM8,HNMT,KCNN1,AFF1,ADAM22,MYO7A,NF1,CNOT4,NOVA2,PBX1,RETREG1,PKN2,RGS10,FBXW7,ZFP30,FRMPD1,ASAP3,KANSL3,SNCA,DOK5,VAMP1,ASTN2,DNAH7,VLDLR,LAT2,ZNF45,SPHK2,PARP6,KCNAB1,UBE3B" Drug 6352_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "RBM10,MRTFA,APLP1,APOC1,APP,CFLAR,MTMR2,TAOK2,SLITRK5,DCAF4,DCAF8,ZNF337,RUSC2,LYPD1,FCGRT,FGFR1,DENND2A,TMEM8B,GPER1,IL11RA,MAP4,ZNF862,NUCB1,PC,MBOAT7,FA2H,APTX,SYTL2,RAB3IL1,SH3TC2,MAPK12,SBF1,PEX26,KDM4D,CCDC88A,TMCC1,TNIK,SPTAN1,ZBTB43,STX1A,KANK1,ARHGEF9,PLCB1,TMEM121,TSC2,ZKSCAN5,LMF1,NDRG4,PHTF2" Drug 2090_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "C1QTNF1,MRTFA,APP,ALDH4A1,ATP2A2,CAST,ARHGAP22,KIAA1549L,COL9A3,AATK,SDC3,PLPPR4,EDNRA,HIPK3,EFNA3,SORBS3,FOXG1,DLL3,B4GALNT1,GLYR1,POLL,GPR19,GUCY1B1,BACH2,HSF2,MEF2C,GIT1,NF1,CNOT4,PIK3CD,STRN3,RC3H2,BCAS3,PTN,RAD52,RGS10,ZNF821,PKNOX2,SPTB,ZBTB43,JMJD6,COBL,CHST8,MTMR14,TK2,TRPC1,TRPC3,SEMA3B,RNF170" Drug 2899_DN Ajmaline [4360-12-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PLA2G6,C1QTNF3,DOC2A,AMT,APBA2,APC,BCAS1,CLU,CREM,GREB1,NOS1AP,DNM1,TRAPPC9,DYRK1A,CNNM1,EFNA3,LRRC23,F3,KAT8,FHL1,PDLIM5,TRAF3IP2,TJAP1,KHK,LSS,ADAM22,NTRK2,RETREG1,LRP12,PPP5C,PRKAR1B,SBF1,SUPT20H,SH3BP2,SYBU,ABLIM3,ZNF365,CXXC4,ZSWIM8,INKA2,STX1A,TCF7L2,TK2,HEY2,TMOD1,RPRM,VGF,ZNF24,SMIM8" Drug 2822_DN Benzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AMPD3,GAS7,MARK4,CADM3,BMP7,RUNX1T1,CBFA2T2,REPS2,PICK1,CSF1,SIPA1L1,SPOCK2,CDON,DSCAM,EDNRB,EIF4G2,NCALD,TUBB4A,DLC1,FHL1,ALDH1L1,GPR22,HMGB1,KCNN2,KHK,MMP16,MX1,ZNF862,NEK1,PIK3CD,RETREG1,WDR25,RAB3A,RAD52,ZDHHC14,NEK11,LIMCH1,MAPKBP1,WDTC1,ARHGAP26,INKA2,PHLDB1,SYNE1,HEY2,VIPR2,ZIC3,SLC30A3,KCNAB1,SSPN" Drug 3417_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABR,SLC12A5,AK2,LTBP4,AMPH,CDC42BPA,ATM,ALDH7A1,CFLAR,GYG2,CAMK2G,ZMYM4,ASIC3,TAOK2,AKAP7,DAPK3,ZNF804A,CDON,DRD1,SGK2,SORBS3,STX2,FAM49B,HBS1L,SIGLEC8,SEPT9,GNAO1,GRM1,HRH3,LSS,MIA2,ADAM22,RAB3IL1,RAD52,ZDHHC14,RGS10,GSTCD,EMID1,WLS,BTBD7,SPART,SS18,ATP11A,IQCE,PCDHA5,TGFBR3,CABIN1,SPHK2,KCNAB1" Drug 6656_UP Cholecalciferol [67-97-0]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "RALGAPA1,ADD2,SEMA6A,APAF1,CDC14B,ASCL1,SLC4A4,CFLAR,SYNJ1,BAIAP3,HAP1,RUNX1T1,DNAJB5,EDRF1,SRGAP3,DUSP9,ING4,ETV1,FABP7,FGFR1,BAIAP2,PRELID3A,GABRA2,GAD2,ADAMTS13,AP4S1,ATXN2L,HSD17B1,ITIH2,KCNN1,LAMA2,NELL2,CLDN11,PURG,MAPK8,FOXRED2,SALL1,SH3BP2,PKNOX2,SLN,ZHX3,BEX1,ATP10B,VAMP1,PCDHGB6,TLR4,CADM1,STMN4,KCNAB1" Drug 1073_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,DGKD,NCOA1,ATM,STX16,ATP6V0A1,FUBP1,C5,HIP1R,REPS2,FOXN3,LHX2,NCOR1,LRIG1,FEZ1,ARHGAP32,GIT2,SMG7,DLG3,OPTN,SORBS3,ERBB2,GFER,GHR,HTATSF1,CLASRP,MAN1B1,KCNJ3,MMP16,SLC11A2,OGG1,KCTD15,SYTL2,RAP1GAP,ROBO1,ATXN1,ATXN7,PDZRN3,SYT1,TCF7L2,KCTD2,PARD3,KAT6B,SSBP2,UBE3A,UBTF,MTCH1,PRDM2,IFT88" Drug 1428_DN Nimesulide [51803-78-2]; Down 200; 13uM; HL60; HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ACTN2,APC,APP,SEMA4G,ATP2B1,KRIT1,CCNT1,SRSF11,CHRNB2,SOCS5,DCAF8,ZEB2,SMG7,FEM1B,EFNB3,ABI2,ERCC2,DENND4A,VPS26C,EZH1,ACSL4,KIAA1109,SEC23B,GPR153,STAU2,FYN,STAG2,GLS,PRRC2B,DIDO1,NR3C1,LAMP2,MPP2,PTOV1,NEK1,RETREG1,CNNM2,PEX5,CLIP1,BCAN,ZCCHC24,UNC5B,VPS13A,TACC1,KIAA0930,SZT2,KCTD2,CABIN1,ST7" Drug 7296_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASPHD1,CDC42BPA,CDK10,PPP4R4,MARK4,ASTN1,SCARB1,CACNA2D2,CHN2,RAB26,HDAC9,MFAP3L,RUSC2,EDNRB,SIDT2,COQ7,RRAGB,EZH1,KIAA1109,IQCG,TRMO,FYB1,GPER1,ELOVL5,IL6ST,LIG4,MGAT3,MYCN,NOVA1,CCSER2,SLC25A23,TMEM231,UEVLD,PAQR6,SCN8A,AMBRA1,ST6GAL1,PPP4R3A,TMCC1,SOX2,TNIK,DDN,MAPK8IP3,EXOC7,ZEB1,DOCK9,ZFPM2,CABIN1,PRMT8" Drug 1975_UP Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NDRG3,ANK2,DGKD,APP,ARNTL,KRIT1,TJP2,QKI,CHD1L,SOCS5,CTH,RUBCN,DCAF8,KIAA0586,ZNF804A,HP1BP3,ING4,FKTN,ARFIP1,TXNL4A,DBF4,LILRA2,IRAK3,NAP1L1,NRGN,NTRK3,SETD4,OMG,SMOX,STRN3,RETREG2,PPM1B,PPP2R5C,RAP1GAP,ARID4A,TCP11L1,HSPA4L,KBTBD4,ELMO2,EMC1,SPP1,EHBP1,TCF7L2,AHCYL2,SIRT1,VIPR2,ZNF24,ZNF189,EVI5" Drug 7310_DN Chenodiol [474-25-9]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "MTUS1,CDC42BPA,APOC1,PPFIA3,MARCH3,MARK4,CFLAR,ST3GAL5,ARHGEF2,CPS1,KLHL3,SGSM2,TENM1,MRNIP,EPHA5,SPEG,B4GALNT1,AHDC1,GPM6B,SLC2A6,IL11RA,DIPK1A,L1CAM,NF1,NPR2,SLC11A2,SAMD9,PTPRN2,RAB3IL1,SH3TC2,RAP1GAP,RPS6KA2,RXRA,SBF1,ITSN1,KBTBD4,SMARCD3,TTC17,CDK19,ELOVL4,PHLDB1,JMJD6,IQCE,SZT2,AHCYL2,ZNF34,R3HDM1,TRPC1,MPPE1" Drug 5904_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADORA1,MRTFA,APBB2,PPFIA3,RGS20,ATP2A2,CADM3,CACNA1D,CCKBR,USP2,INA,ARHGAP33,CLGN,FOXN3,LHX2,SULT4A1,RIMS3,DAPK3,RASGRP2,CORO2B,FCGRT,FGFR1,FGR,GABRA2,RND1,SHISAL1,ITIH2,LAMA2,NOS1,KCNK10,PLTP,MAPK10,PLPPR1,C1orf54,ENOX1,KCNIP2,SEMA6D,SLC1A7,ZNF423,ATP10B,COLGALT2,PHLDB1,PCDHGA10,TMEM151B,SEZ6L,TMPRSS5,OSBP2,VAV2,WIPF1" Drug 7076_UP PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "APBA2,APBB2,ALDH7A1,SOCS6,CLCN3,OSBPL3,USP6NL,FAM131B,DCAF8,SGSM2,KBTBD11,CNNM1,PLEKHO1,BAIAP2,CSPG5,ERAP1,DISC1,INPP5K,GPER1,MIA2,SLC11A2,OGG1,CDIP1,POLG,PTPRE,RAB3A,ZDHHC14,MRPS18A,MYH14,ZNF671,MCMBP,SAFB,SBF1,ZFP30,DOCK10,DZIP1,SLC6A8,SMARCD3,SEPT8,PHLDB1,TCF4,TCF7L2,SZT2,AHCYL2,TGFBR3,CABIN1,METTL3,NPDC1,UPF3A" Drug 336_DN nitrendipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "KDM5D,ADCY6,LTBP4,BIN1,DGKD,CADM3,MTMR2,BAIAP3,HIP1R,JAM2,NIPBL,AKAP12,PDE4DIP,TSPAN5,HSD17B14,F5,ZMYND10,FOLR2,KHDRBS3,NEU3,MALT1,STON1,FAM107A,ARHGAP19,IGF1,KHK,MBD1,MYO7A,SATB1,SH3BP2,FERMT1,KDM4B,SCN3B,EMC1,MYCBP2,THSD1,ANKRD12,EXOC7,TRIM2,WASHC4,DOCK9,CDH22,TRIO,TUBB1,AMOT,VAV2,LMF1,WNT7A,MPPE1" Drug 6597_UP "16, 16-dimethylprostaglandin E2 methyl acetate solution; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "PLA2G6,CDC42BPA,APP,PPP4R4,CADM3,ARHGAP33,DNAJB5,QKI,PICK1,CNTNAP2,DAPK3,TMCC2,DNM2,SHANK1,EFNA3,EFNB3,IRAK4,PLEKHO1,DMTN,KAT8,INPP5K,GPER1,HSD17B1,ITIH2,KCNH2,KCNJ3,NPR2,PDE4A,PIK3CD,PPP2R2B,PPP5C,MAPK7,WDR25,MYH14,ROBO1,RPS6KA2,KCNIP1,PPP1R9A,SYBU,FAM214B,SMARCD3,SS18,FBXW11,CABIN1,ZKSCAN5,CADM1,WNK1,SEMA3B,NAV2" Drug 7280_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADCY6,GAS7,LGR5,SLC4A4,KRIT1,LHX2,RAB28,QKI,CSF1R,SOCS5,RUSC2,SMG7,DTNA,E2F5,AASS,PLEKHO1,ACSL4,ATP8A1,TESK2,FLT1,TRMO,NCKAP1,TMEM8B,SYT17,GPER1,KIF5C,MAN2A2,NF1,NOS1,SLC25A23,LRP12,MED1,MAPK7,ROGDI,GTDC1,ZFP30,DOCK10,SMARCD3,TMCC1,WDTC1,SOX2,ARHGAP26,ADGRL3,TK2,TRPC1,HIRA,MICAL1,WNT7A,XRCC4" Drug 919_DN carbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ABHD6,CDK10,SYNJ2,GYG2,OSGIN2,KYAT1,QKI,NCOR1,CTH,PPP6R2,DBT,LYPD1,PARD6A,RABGAP1L,MAMLD1,PLEKHA1,ANKMY1,FHL1,NOP56,FAM49B,MPP6,GHR,TXNL4A,GPER1,SLC2A6,NF1,NPR2,PC,KCTD15,PRPH,SAMD9,ROBO1,ASAP3,SYBU,SLC6A8,SIRT2,SLC15A2,ZKSCAN3,SMARCD3,ERC1,ZBTB43,LHPP,SYT1,ASTN2,AHCYL2,TMEM121,VGF,MPPE1,MVB12B" Drug 1885_DN Troleandomycin [2751-09-9]; Down 200; 5uM; PC3; HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "RBM10,KIDINS220,APLP1,DGKD,APP,MARK4,EIF4G3,FUBP1,NFS1,CHRNB2,CNOT8,NIPBL,ELAVL2,STX2,CAMSAP1,SEC23B,STAU2,MPP6,OGA,TRAF3IP2,BTN2A1,PSIP1,RNFT2,HNMT,DIPK1A,NEK1,OGDH,LRP12,MAPK3,MAPK9,PTHLH,SUPT20H,SLC11A1,ELMO2,SON,CAND2,SRPK2,GANAB,GSE1,TBL1X,TCF12,HEY1,TJP1,TMPO,TRIO,PLPPR2,CLDND1,ZNF189,FTSJ1" Drug 4216_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "CFLAR,ARHGEF7,KRIT1,CNOT8,QKI,BAG4,VCAN,DBT,CNIH3,EXOG,DTNA,RGS17,ETV1,FER,ANKFY1,TRMO,GRM1,DIPK1A,KIF5C,LIG4,TAGLN3,MTR,PAK3,CCSER2,RETREG1,PLCD1,STRN3,RAP1GAP,ZCWPW1,FBXO11,SLC1A3,TMCC1,TNIK,SPTAN1,TROVE2,SAMSN1,NXT2,ARHGEF9,PLCB1,WWC1,ARHGEF12,ZNF34,RUNDC3B,SSBP2,UBTF,NDRG4,KCNAB1,MPPE1,SMIM8" Drug 7023_UP Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "KCNAB2,APBB2,PPFIA3,ARHGDIG,PDE8B,DNAH17,SCAPER,BAIAP3,CACNB4,CAMK2G,FADS2,GPRASP1,RIMS3,DAPK3,PHF20L1,MRNIP,PCOLCE2,EPB41L2,PIPOX,FAM198B,KIAA1109,TPK1,GPER1,GRIK5,INPP5B,MGAT3,MKLN1,SETD4,PDE3B,ZDHHC14,RFX2,EXD2,ROM1,FBXW7,SAFB,SBF1,PPP1R9A,PREX2,PEX26,CDK5RAP2,SNCA,STX1A,KAZN,ROBO3,R3HDM1,FAM155A,ZNF45,SLC30A3,ST7" Drug 4681_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "DPF1,ABAT,ACHE,MRTFA,MARK4,ADAM23,ADGRB2,MPDZ,CACNG1,CAMK2B,CBS,USP2,GPR37L1,ADGRG1,CHGA,TAOK2,FAM131B,C2CD2L,AK5,DPH1,DRP2,ZNF589,ANKFY1,USP21,FYB1,FYN,GAB1,GAD2,SIGLEC8,LYVE1,POLL,SPACA9,HLF,MATN3,P2RY13,NOVA2,ENOX1,TCP11L1,SCN2B,SLC1A6,SLC6A9,MAPK8IP3,PCDHGB6,TMEM121,GPR161,R3HDM1,NSD2,ZNF24,SEMA3B" Drug 317_UP N-phenylanthranilic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AMT,CDC42BPA,APBA2,CDK10,CHRD,REPS2,CHRM4,PCYT1B,CP,OSBPL3,PDE4DIP,TM9SF4,AK5,SIDT2,EIF4G2,HSD17B14,ERCC2,CACNG2,GAB1,ALDH1L1,SRCAP,MCHR1,AP4S1,NCKAP1L,ATXN2L,NNAT,NPY,NPTX1,DDR2,OPCML,CAMKV,LRRN3,PPP2R5C,KCTD17,ZNF821,ITSN1,FERMT1,FNDC3A,SLC1A3,RPH3A,SLC8A1,SNCA,NMNAT2,SSTR1,TCF7L2,TRIO,VIPR2,WNT7A,SLC13A3" Drug 4790_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AP2A2,BIN1,ANK3,ASPH,ATM,CFLAR,SYNJ2,MTMR2,CACNA1D,SOCS6,NMT2,CREM,SIPA1L1,PDE4DIP,GIT2,DTNA,EDNRA,FECH,NOP56,INPP5K,TXNL4A,GPD2,JAK2,KIF2A,IPO5,MIA2,MITF,NFYA,PDCD2,PLXNB1,LRP12,PRODH,GON4L,TMEM104,WDR25,PTCH1,FAM120C,FOXRED2,ZNF430,SHANK2,INTS9,SPATA7,TSPYL2,SATB2,CABIN1,RUNDC3B,ZKSCAN5,XRCC4,PCBP4" Drug 2549_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ASIC1,APC,APP,CDK10,NCOA1,CAPN3,CBFA2T2,ARHGAP33,PLAA,STOML1,CREM,SIPA1L1,ZNF337,DTNA,FEM1B,PLXNC1,MRNIP,RASGRP2,ZNF589,ANKFY1,CGREF1,GABRA4,HBS1L,RAB40B,MAP4K5,NCKAP1L,MEF2C,NF1,PLTP,PPP5C,SIDT1,GON4L,ZDHHC14,RGS3,FAM214B,BTBD7,WDTC1,UHRF1BP1L,NCDN,MAPK8IP3,STX1A,KAZN,TCF7L2,THRA,TNNT1,CDK20,UBE3A,PLPPR2,LMF1" Drug 1743_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; HL60; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "NDRG2,CNTNAP1,APP,ARNTL,CADM3,ENTPD6,CLOCK,CRYM,TM9SF4,GIT2,KIAA0753,DNM2,DPH1,SIDT2,EGR3,ING4,PLEKHO1,CEND1,ECSIT,TRAF3IP2,GAP43,ALDH1L1,SRCAP,RUNDC3A,ACOT7,JAK2,KIF5C,VWA5A,MYT1,OCRL,NLE1,PLCB2,PLCD1,GON4L,RNASEL,SAFB,ATXN7,ZNF821,FNDC3A,KBTBD4,NXT2,PLCB1,PHF24,PARD3,ZMYND8,CADM1,XRCC4,ZNF24,GDPD5" Drug 1756_UP Tetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; HL60; HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ADORA1,AGT,APOC1,BCL7A,CD38,ENTPD6,NEURL1,CNTFR,CPS1,FEZ2,DNM2,ERBB2,ERCC2,AFF2,CRCP,RAB30,TDRKH,DIDO1,CACFD1,PADI2,ACOT7,KIF5C,MAP4,GIT1,NELL2,ODF2,PALM,PLCB2,PACSIN1,PPP5C,PRPSAP2,CCDC40,RGS12,ZNF671,TCP11L1,NTNG1,PKNOX2,CCDC88A,SP4,THSD1,TCF4,TMEM151B,NSD1,RBFOX2,HSPBP1,NPDC1,ATP6V0E2,ZNF142,LAMP5" Drug 2054_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "ACTN1,ADCY6,MRTFA,ARRB2,ASPH,SPAG9,AP4M1,LHX2,AKAP7,CHD1L,HINFP,ARHGEF4,GNE,FGFR1,BAIAP2,TRMO,CRCP,GNAS,PCLO,ARHGAP19,IL6ST,SMAD1,NUCB1,CDIP1,POLG,PRKAB2,BCAS3,TMEM260,PAQR6,SBF1,SEC14L1,SH3BP2,PEX26,SPTAN1,CEP68,TTBK2,VPS13A,TBL1X,TCF7L2,GPR161,TMPO,HIRA,NPDC1,XRCC4,ZNF24,EVI5,SMIM8,RNF170,SSPN" Drug 2947_UP Risperidone [106266-06-2]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "AGT,CDC42BPA,APOC1,KIF1A,CALB2,ARHGEF10,CNIH3,SPOCK3,CELSR3,SORBS3,ELN,VPS13B,RASGRP2,CEND1,CAMKK2,PRELID3A,SEPT9,WASF3,GATM,TJAP1,KIF5C,SMAD1,AFDN,CNOT4,NLE1,MYH14,TCP11L1,RYR1,GALNT10,RASA3,FUZ,CCDC92,EPN2,BTBD7,ARHGAP26,INKA2,PDLIM2,CUX2,TRIM2,SZT2,SLC44A1,TMOD1,KCTD2,RBFOX2,CDK20,UBTF,FLRT1,SLC13A3,EVI5" Drug 3140_UP Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.40E-04 1.00E+00 4.88E-03 5.55E-02 49 198 "DPF1,KIDINS220,AGT,CDC42BPA,BCAS1,AQP4,CACNA1G,LDB2,CBFA2T2,CHN2,LHX2,EPS15L1,CREB5,CRYM,CHD5,DCAF4,RUSC2,SPOCK3,EEF1A2,CELSR3,SORBS3,ZNF549,F5,GPR153,GABRA2,ERAP1,GLRB,GPR22,GRM7,AP4S1,KCND3,LSS,MDFI,SCAMP5,AFDN,MYCN,OMG,LRRN3,RAD51D,ZMAT4,RGS12,TTLL7,SLC11A1,SS18,WSCD1,TJP1,TK2,RBFOX2,URM1" Drug CID000004826 pinacidil Stitch 6.41E-04 1.00E+00 4.88E-03 5.55E-02 26 87 "ADORA1,ADORA2A,ADORA3,AMH,DYNLL1,CACNA2D1,CTH,ABCC9,EDN1,EDN3,GUCY1A2,GUCY1B1,KCNA2,KCNB1,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNK3,NOS1,NPPA,NPR2,PRKCB,PRKCG,ABCC8" Drug 2899_UP Ajmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ASIC1,ADRA1D,AK2,GAS7,ARHGDIG,ATM,SLC2A11,CFLAR,SCAPER,NEURL1,ARHGAP33,PICK1,NRG2,CPS1,ENTPD4,SPOCK2,ERBB2,DLC1,OLFM1,GABRA2,NEU3,C1QL1,GLS,GPER1,NR3C1,KCNH2,KIF5A,BCO1,NNAT,CNOT4,SLC25A23,POU3F2,PRODH,FAM120C,TMEM206,FRMPD1,IQSEC2,JMJD6,TCF4,KIAA0930,TMEM121,TRIO,TRPM2,ZMYND8,SYNC,GDPD5,ITM2C,SSPN" Drug 4426_DN 3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "AK2,BIN1,GAS7,APLP1,FAM131A,PDE8B,ATM,CADM3,CFLAR,FOXN3,RIMS2,RASSF2,RIMS3,SPOCK2,RUSC2,SMG7,SIDT2,GPR153,OGA,SRCAP,RUNDC3A,RND1,PCLO,NR3C1,GRM1,ICA1,KCNN1,MOBP,ADAM22,NOS1,CNOT4,PIK3CD,RETREG1,NLE1,MINDY2,PRKAR1B,MAPK8,EMID1,ASAP3,CXXC4,ZCCHC24,RBM26,ATP11A,PCDHGA10,SLC44A1,HIRA,VGF,KCNK12" Drug 4996_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "SEMA6A,CDC14B,CFAP410,BRSK2,NEURL1,ARHGEF6,CSF1,RUSC2,SMG7,SLC12A6,RCAN1,DYRK1A,EZH1,NRN1,FGFR1,CAMSAP1,AFF2,PDLIM5,OGA,ALDH1L1,SRCAP,GPM6B,SPACA9,GRIN1,IL6R,KITLG,PC,PLPPR1,EMID1,SH3BP2,SLA,RPH3A,MAPKBP1,IZUMO4,PEG10,THSD1,INKA2,PLCB1,SYN2,PCDHGB6,CRTC1,TMEM121,HIRA,FLRT2,SLC30A3,EMSY,SEMA3B,SLC17A7" Drug 3164_DN Albendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "MRTFA,PPFIA3,MARK4,ATM,KIF1A,BCL2L2,BCL7A,CFLAR,SYNJ1,CACNA1D,CAMK2G,PLEKHB1,TAOK2,PDE4DIP,SDC3,SMG7,RABGAP1L,KBTBD11,MRNIP,POLR1B,FGFR1,SEMA4D,MPP6,RNFT2,IPO5,NASP,NUMA1,RETREG1,CNNM2,ZSCAN32,MSANTD2,RGS3,ROBO1,TRAPPC13,FNDC3A,WDTC1,NCDN,EXOC7,TCF7L2,AHCYL2,ZNF34,BHLHB9,TPD52,HIRA,RPRM,EVI5,NAV2,UBE3B" Drug 6753_DN Caffeic acid [3331-39-5]; Down 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "NDRG3,CDK10,ARHGDIG,ARRB2,ASPH,ATP1A3,STX16,KIF1A,CANX,CBFA2T2,ARHGEF2,CHM,RAB28,NRXN3,TBC1D5,BRINP1,HP1BP3,RUSC2,EFNA3,CELSR3,ETV1,RRAGB,ST3GAL6,FCGRT,ANKFY1,GAB1,ZNF44,GCNT2,GPD2,EML4,KCNN1,NF1,PLXNB1,MAPK7,SYTL2,RGS10,FBXW7,CLIP1,FAM214B,CCDC88A,SLC20A2,ZNF667,WDTC1,GSE1,TRIO,UGT8,NSD2,PHTF2" Drug 3925_DN Deltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ALCAM,LTBP4,FAM131A,PPP4R4,ALDH7A1,MTMR3,CBFA2T2,CHM,CNTFR,AKAP7,SLC4A7,NECTIN3,CSF1R,DUSP9,EDN1,HIPK3,FCF1,MBNL2,EPB41L2,LRRC23,EZH1,FAM49B,ARFIP1,RUNDC3A,EML4,KCNF1,KCNH2,KCNMA1,MAP4,MDM4,KITLG,NELL2,PCDH9,PLCD1,MINDY2,WDR25,ZDHHC14,NEK11,FBXW7,SELL,DOCK10,FAM214B,SLN,ZCCHC24,ARC,KIAA1107,ZNF24,PHTF2" Drug 3104_DN Nilutamide [63612-50-0]; Down 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "PLA2G6,PPFIA4,AZGP1,BMP7,LDLRAD4,CDO1,B4GALT6,CREM,GPRASP1,SIDT2,VPS13B,COQ7,LRRC23,ERCC2,F5,KIAA1109,CAMSAP1,FLT1,GAB1,GABRA4,ZNF44,GATM,GRM1,IL6ST,KIFC3,LAMA2,NF1,NINJ2,CCSER2,PTPRO,CEP97,RAD52,ZNF821,CPEB3,BCAN,SLC2A5,SLC6A8,ZCCHC24,DBNDD2,STX1A,VAMP1,CAMSAP2,TCF7L2,CRTC1,ZNF34,RBFOX2,REEP1,FAM13C" Drug 3814_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "APC,ATM,NRP2,CFLAR,BMP7,BTRC,CBS,SEPT7,ARHGAP33,CACNA2D2,CLCN4,IFFO1,TCEAL2,FAM13A,DMTN,PRELID3A,OGA,GNG3,GNG4,GPM6B,IL6ST,INPP5B,ITGA7,ITIH2,LSS,MDM4,OGG1,PIK3R1,PLCD1,EPN1,MINDY2,GRAMD1C,MCMBP,TRAPPC13,SUPT20H,DOCK10,BCAN,PREX2,ZNF334,BTBD7,OGDHL,SNCA,TBCEL,GPR161,VIPR2,TFIP11,PCBP4,DPF3" Drug 6751_DN Ceforanide [60925-61-3]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ABR,ARID1A,MRTFA,ASPH,ATP1A3,CANX,CHM,PLAA,HOMER3,CPS1,ENTPD4,DZIP3,TBC1D5,HP1BP3,SPOCK3,EFNA3,EPB41L2,FCGRT,ANKFY1,OGA,ZNF44,EML4,INPP5B,JAK2,LSS,MAP4,CNOT4,OCRL,PLCD1,STRN3,MINDY2,ZCWPW1,RGS10,FBXW7,CLIP1,TMEM156,SFPQ,FUZ,FNDC3A,SLC6A8,EMC1,TAB2,SS18,GSE1,UBTF,UGT8,NSD2,PHTF2" Drug 783_UP forskolin; Up 200; 50uM; HL60; HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "GRAMD1B,ADORA2A,ANXA7,GAS7,ARRB2,CFLAR,CCNT1,CD38,FOXN3,TMEM184B,NIPBL,AATK,MICAL2,VCAN,RABGAP1L,FEM1B,USPL1,KAT8,GART,COPS8,LILRA2,GRIK5,MBP,AFF1,PDE3B,PDE4B,SSH1,RETREG2,PRPH,PTPRE,RAP1GAP,MRPS18A,RXRA,ARHGEF40,KIF21B,FNBP1,RBM26,EPB41L3,NXT2,FAM208A,FBXW11,WASHC4,SPX,KCTD2,ZMYND8,LAT2,CLDND1,WNK1" Drug 5273_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "RALGAPA1,ACTN2,NME5,AK2,APBA2,APBB2,GAS7,APOC1,ATM,CFLAR,CBFA2T2,ARHGAP33,CHM,CSF1R,EXOG,DRD1,FCF1,EGFR,ING4,EZH1,OGA,ZNF44,INPP5K,GNG3,KCNH2,KHK,MBD1,ADAM22,NDUFA5,LRP12,MBOAT7,PPP2R2B,PLPPR1,RGS10,RGS12,SLC25A36,PREX2,POGZ,TACC1,KIAA0930,RPGRIP1L,AP4E1,ZNF34,KAT6B,CDK20,ZMYND8,WNK1,SSPN" Drug 4558_DN CP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ASPHD1,AP2A2,NME5,BIN1,KCNAB2,SEMA4G,ARHGEF1,ARMC8,SLC4A8,CSNK1E,FAM131B,MFAP3L,RUSC2,LYPD1,DLG3,EFNA3,SORBS3,SPEG,ANKMY1,EZH1,TRAF3IP2,DENND2A,SYT17,DISC1,GPR17,GRK4,HAS2,KLF12,GIT1,NDP,PBX1,STRN3,RC3H2,PTHLH,PTPRN2,DOCK10,DZIP1,KDM4C,CDK19,ZBTB43,SPART,GSE1,TBL1X,ARHGEF12,DNAH7,XRCC4,HPS4,ZNF248" Drug 6732_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "AP2A2,AGT,MRTFA,ASTN1,CFAP410,MAP7,CHGA,CREM,ABCG1,CTH,SEC14L5,MFAP3L,EDNRB,HIPK3,FCF1,ING4,COQ7,FGFR1,GAD1,NEU3,ZNF276,HPGDS,GPR17,GPER1,EML4,GPR45,HNF4G,SHISAL1,MDM4,KITLG,AFDN,RETREG1,MAPK8,IL17RB,SLC1A7,SNAP25,PDZRN3,SPP1,ASTN2,TCF4,DOCK9,DNAH7,TK2,TRPC1,ZNF24,PRDM2,PRDM10,EPM2A" Drug 3098_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ADRA1D,MRTFA,ATP6V0A1,KIF1A,BACH1,SOCS6,RAB28,PLAA,AKAP7,ARHGEF10,CTNND1,GPRASP1,RIMS3,DTNA,HIPK3,MBNL2,FER,IQCG,PDLIM5,CAMKK2,GABRA2,GALC,HTATSF1,PRRC2B,GPD2,IL11RA,KPNA5,AFDN,ZNF862,NFYA,CDK14,RETREG1,PLEC,PLTP,PRKAB2,PTAFR,DPF2,TMEM206,SEC14L1,FNDC3A,SLC1A7,PEX26,KIF1B,CDK19,TMPO,PLPPR2,EMSY,PRDM2" Drug 3845_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "NDRG2,ADORA3,SEMA7A,APAF1,KCNAB2,ASPH,BRINP2,CHRD,MTMR3,CACNA1G,CCNT1,ZFYVE9,PICK1,CRY2,RASSF2,DAPK1,DAPK3,CTIF,NR1D2,FCF1,ERBB2,CEND1,KIAA1109,CAMSAP1,C1orf61,ANKFY1,CAMKK2,FUT9,GLYR1,ELOVL5,IL6ST,KIT,LSS,KITLG,NEUROD1,NF1,NINJ2,NUMA1,PDE3B,TMOD2,PTPRN2,DOCK10,PEG10,ZBTB43,TROVE2,ATP11A,SMG6,UBE3B" Drug 1412_DN "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; HL60; HG-U133A" Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ACTN2,AP1B1,PKP4,SHTN1,ATM,BTK,CHRNB2,TJP2,SLC4A7,CSNK1G3,TM9SF4,GIT2,ZEB2,G3BP2,RCAN1,EFNB3,KCTD3,CEND1,WAC,POMT1,TRAF3IP2,GART,SESN1,NXPH3,IFI16,MAP4,MBNL1,MKLN1,SLC11A2,RC3H2,RETREG2,PTPA,CNNM2,ATXN2,SGK1,CCDC88A,ZCCHC24,FNBP1,CLASP2,FCHO1,CEP68,GSE1,ANKRD12,ZEB1,TMPO,METTL3,TSN,UBTF" Drug 7545_UP semustine; Up 200; 100uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "BRAP,PLA2G6,ASPH,ADGRB1,MPDZ,BTRC,CHRNB2,TAOK2,CREM,RUBCN,GPRASP1,C2CD2L,EFNB3,LRRC23,STX2,CDKL3,EZH1,BAIAP2,CINP,B4GALNT1,SRCAP,TDRKH,CACFD1,FICD,TJAP1,ITGA7,ITPKA,MDFI,SLC11A2,PDE4D,EPN1,TNPO2,SAMD9,PTHLH,GAL3ST4,TRIM68,ZNF671,TRAPPC13,HSPA4L,SCG5,PEX26,UNC5B,ASTN2,TIAM1,TK2,CDK20,SPHK2,EMSY" Drug 4431_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "AMH,APAF1,STX16,KIF1A,PROM1,LDLRAD4,RUNX1T1,CBS,MAGI1,ZFYVE9,STOML1,TCEAL2,NCOR2,CSF1,NCAN,RIMS3,MAGI2,EGFR,ETV1,ATP8A2,RND1,RAB30,MSL3,CACFD1,PTGDR2,KCNB1,KCNN2,ADAM11,MGAT3,AFF1,NEFM,NNAT,PALM,PDE3B,PNMA3,TNPO2,GAL3ST4,EMID1,SCN8A,LIMS2,PKNOX2,ZHX3,NPAS3,MCF2L,SZT2,PCDHGA10,TPM1,SLC17A7" Drug 6678_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "RALGAPA1,PKP4,PRX,CFLAR,SYNJ1,BTRC,CACNA2D1,SCARB1,VAX2,DNAJB5,FAM149A,FEZ1,DAPK3,MAGI2,SRGAP3,DTNA,EDIL3,ING4,ETV1,FGF1,C1QL1,GSN,KCNJ4,KCNN1,KIT,LMO2,MATK,ADAM22,NCAM1,NTRK2,PAK3,PDE4D,TNPO2,LRRN3,PTPRN2,TMEM231,HKDC1,PKNOX2,SLC11A1,BEX1,NPAS3,PLCB1,COBL,CRTC1,R3HDM1,LILRA4,FLRT2,PRDM2" Drug 3139_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "RALGAPA1,BIN1,ANK3,APBB2,APOC1,MTMR3,ARHGEF1,DNAJB5,CNTN1,PDE4DIP,RUBCN,SPOCK2,DBT,MRNIP,VPS13B,ETV1,PTK2B,CAMSAP1,ATP2C1,GAA,GAB1,ADAM28,GLS,MUM1,TJAP1,IL6ST,IL11RA,LAMA2,MAP4,NRCAM,OXTR,PFKFB4,PIK3R1,PLCD1,PLCL1,CNNM2,CNTLN,SH3BP2,SLC6A8,ZCCHC24,DNMBP,TCF7L2,KAT6B,TNS1,RBFOX2,TRPS1,LMF1,AAAS" Drug 982_UP (-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ASIC1,ABHD6,NDRG2,ARNTL,BCL7A,CFLAR,BTRC,B4GALT6,RAB28,RAB26,SIPA1L1,DZIP3,PHF14,CTH,DBT,DNAJC6,SGSM2,KBTBD11,ACOT8,DSCAM,ANKMY1,TDRKH,GPR19,GPR37,KIF3A,RNFT2,JAK2,KIF5C,MAPT,MPP2,SLC11A2,PALM,PMP22,PRKAR1B,RAB3IL1,RGS3,TCP11L1,ASAP3,ZNF365,SPTAN1,LHPP,ELOVL4,MICAL1,SF1,REEP1,MAP3K12,MVB12B,SMIM8" Drug 4712_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.55E-02 48 193 "ADORA1,AMPD3,CDC42BPA,PLA2G4C,ARHGEF1,DGKI,CDH2,KIAA1549L,WHRN,CRMP1,ARHGEF10,NOS1AP,RIPOR2,DSCAM,RCAN1,EN2,FGFR1,FOXG1,GAD1,ALDH1L1,SRCAP,GLYR1,PCLO,HPSE2,SYNPO,KCNF1,ADAM11,BCO1,NF1,CNOT4,SERPINI1,PMP2,PTAFR,PTX3,RAD52,C1orf54,TCP11L1,SLA,PHLDB1,VPS13A,PCDHA6,TNS1,AMACR,NT5M,SEMA3B,NAV2,FAM13C,SSPN" Drug 2679_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 6.43E-04 1.00E+00 4.88E-03 5.56E-02 45 178 "CLK4,C3orf14,MTUS1,SYT13,AMPD3,APP,ATP6V0A1,TAOK2,TPP1,ABCG2,CREM,USP6NL,ZNF337,DGKG,DBT,FAM13A,MBNL2,ENO2,KIAA1109,CAP2,AGAP2,PDLIM5,ATP2C1,OGA,GALC,STON1,MUM1,NUMA1,PDE4B,PMP22,LRP12,MBOAT7,PRKACB,MARCH1,ZNF821,HSPA4L,SLC15A2,SPTB,FAM168A,TCF7L2,TGFBR3,DAAM2,TPM1,ZBTB38,FXR1" Drug CID004636050 AC1NE3N8 Stitch 6.43E-04 1.00E+00 4.88E-03 5.56E-02 45 178 "ADCY5,ADCY6,ADCY8,ATP1A2,ATP1A3,SLC4A4,CACNA1A,NFS1,CBS,INA,ARHGEF1,CD38,ASIC3,CHRM1,ATN1,EDN1,EDN3,EPB41,FECH,GALC,GALR1,NFU1,GLS,NR3C1,KCNJ9,KCNJ16,MTR,NPY,P2RY1,PPP2R2B,PRKCB,MAPK9,MAPK10,ATXN7,SCN4B,SCNN1D,SLC12A2,SLC14A1,SCN3B,SST,TAC1,TAC3,TTPA,VIPR2,P2RY12" Drug 5565_DN "ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 6.44E-04 1.00E+00 4.89E-03 5.56E-02 47 188 "ASPHD1,LTBP4,APBA2,BCAS1,SYNJ2,CA12,HOMER3,RCHY1,LRIG1,GREB1,RCAN1,CNNM1,RASGRP1,RBM12,EGR3,VPS26C,ZNF589,FOXG1,C1orf61,MSL3,IL6ST,JAK2,KCNF1,KCNH2,VWA5A,MDM4,MIA2,GIT1,ADAM22,MBOAT7,PPP5C,SAMD9,ZCWPW1,RET,FBXW7,SGK1,SYBU,PREX2,WDTC1,EMC1,SPTAN1,AHCYL2,TMEM121,ZNF34,SEMA3B,ACTR3B,GAN" Drug 4581_UP Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.44E-04 1.00E+00 4.89E-03 5.56E-02 47 188 "ADRB2,BCAS1,PPP4R4,CAMK2B,CANX,ARHGEF2,RAB28,NRXN3,CLCN4,QKI,SLC4A7,CREM,VCAN,PHF14,C2CD2L,SEMA3D,EFNB3,ING4,PLEKHO1,EFEMP1,FOXG1,FLT1,GAB1,GABRA2,ZNF44,ERAP1,SIGLEC8,SRCAP,ICA1,ITGA7,IPO5,MIA2,MMP16,SNRK,PTAFR,PTPRH,RGS12,TMEM156,RASA3,PPP4R3A,SNAP25,TSNAXIP1,TK2,CDK20,ZNF225,NAV3,PHTF2" Drug 6737_UP Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.44E-04 1.00E+00 4.89E-03 5.56E-02 46 183 "AGT,NME5,EPB41L5,BCAS1,FUBP1,IL33,MAP7,SCARB1,ARHGAP33,CACNA2D2,CREM,CTH,MAGI2,TENM1,EFS,ETV1,F5,DLC1,SORBS1,GLYR1,GNG3,IGFBP1,KCNN1,LMO1,MMP16,MX1,PALM,PDE2A,PDE4D,GPR85,PFKFB3,DUSP26,SNRK,PTHLH,RGS12,RIMS1,TNIK,ARHGAP26,ATP10B,CEP68,SYT5,MCF2L,TBL1X,TK2,TRPC3,PARP11" Drug 5221_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.44E-04 1.00E+00 4.89E-03 5.56E-02 46 183 "ARID1A,ADRA1D,MRTFA,DNAH17,MARK4,CADM3,N4BP2L1,AZGP1,BMP7,NEURL1,TAOK2,LRIG1,SDC3,GREB1,CDON,SLC12A6,EFNB3,EGR3,DLC1,GAP43,SRCAP,LYVE1,GRIK5,IL6ST,MAP4,AFDN,ZNF862,NOVA2,PILRA,TNPO2,SAMD9,PTHLH,ZSCAN2,MYH14,ATXN1,SEC14L1,FRMPD1,SPTAN1,TSPYL2,CLSTN2,RGL1,EXOC7,TRIM2,R3HDM1,SEMA3B,TIGD6" Drug 3704_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.44E-04 1.00E+00 4.89E-03 5.56E-02 46 183 "NME5,CDK10,ATP6V0A1,CACNA1I,DLGAP2,ZFYVE9,TPP1,RAB26,HOMER3,NRG2,CSF1R,PDE4DIP,HDAC9,DMD,ATN1,DTNB,ECM2,ING4,RGS17,ST3GAL6,ZNF589,PRELID3A,NSG1,GAP43,SYT17,POLL,IFI16,KCNH2,KIFC3,MIA2,PCDH9,PFKFB2,PFKFB4,BEND5,RASA3,SLC1A6,SLC11A1,SLC15A2,SOX15,FAM168A,SYN2,SYT5,GPR161,TRIO,OSBP2,SPHK2" Drug 1709_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.44E-04 1.00E+00 4.89E-03 5.56E-02 46 183 "BCL7A,CFLAR,C5,SLC4A7,TBC1D5,SMG7,NR1D2,DTNA,FCF1,ZNF589,FER,B4GALNT1,SEPT9,CRCP,SPIN1,IL6ST,MAP4,MITF,GIT1,MYO6,PIK3R1,STRN3,PRKAB2,PKN2,GON4L,TMEM104,TMEM260,PLEKHB2,RGS10,SLC25A36,RPS6KA2,ZNF331,MAPKBP1,TMCC1,KDM4B,CEP68,TBL1X,EHBP1,DICER1,TMPO,ZMYND8,SF1,ZBTB38,WNK1,ST7,FXR1" Drug 6185_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.44E-04 1.00E+00 4.89E-03 5.56E-02 46 183 "GRAMD1B,APAF1,APC,CDC14B,SLC4A4,CFLAR,BTRC,CREM,CRYM,MICAL2,TM9SF4,MFAP3L,SPOCK3,FAM13A,MBNL2,KIAA1109,CAP2,OGA,NEFM,NOS1,NPPA,PCSK5,PDE4B,PDE4D,RETREG1,PMP22,MBOAT7,PRKACB,PKN2,CNNM2,CNTLN,CRTAC1,HSPA4L,SH3GL3,SLC1A7,SLC15A2,RIMS1,LHPP,ATP10B,ASTN2,ZMYND8,LMF1,VSNL1,CLIP2,ZBTB38,PRDM10" Drug CID000002369 betaxolol Stitch 6.62E-04 1.00E+00 5.02E-03 5.71E-02 17 48 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CA4,CA12,CACNA2D1,TBPL1,EDN1,DNER,MAPK3,MAPK4,MAPK7,TPM3" Drug CID000121892 retigabine Stitch 6.62E-04 1.00E+00 5.02E-03 5.71E-02 17 48 "ABAT,ANK3,CHN1,CHRNA4,CHRNB2,SV2A,NTM,GABRG2,GRIK1,KCNA1,KCNA2,KCNC1,KCNH2,KCNQ2,KCNQ3,SLC6A1,ARFGAP1" Drug CID000068933 BT325 Stitch 6.68E-04 1.00E+00 5.06E-03 5.76E-02 14 36 "SYNJ2,ABCG1,DBI,BLOC1S6,DMD,DTNB,GFAP,STMN2,HPS5,BLOC1S2,ATXN7,SLC14A1,P2RY12,HPS4" Drug CID000002433 AC1L1DNZ Stitch 6.78E-04 1.00E+00 5.14E-03 5.84E-02 16 44 "ASIC3,STX2,GABBR1,GAP43,GJB1,KCNA1,KCNA2,PRPH,QDPR,SCN4B,FOXRED1,SCN3B,STX1A,JMJD6,PUM2,ST8SIA2" Drug CID000061671 vanadyl Stitch 6.81E-04 1.00E+00 5.16E-03 5.87E-02 70 307 "MTUS1,AGT,PDE8B,DNAH17,DYNLL1,ATP2B1,ATP2B2,ALDH7A1,MTMR3,ENTPD2,LRBA,CTNND1,MAML1,DNAL1,DLG4,DNAH9,EGFR,ERBB4,PTK2B,FGF1,FYN,BRD8,IGF1,JAK1,KCNJ5,MAG,MBP,MOBP,MOG,MYO7A,OLR1,OMG,PCDH8,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PDGFRA,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTH1R,PTK2,PTPRG,PTPRZ1,MAPK12,SSTR2,CABIN1,CADM1,VAV1,WRN,DNAH10" Drug CID000022251 thioflavin Stitch 6.81E-04 1.00E+00 5.16E-03 5.87E-02 15 40 "SERPINA3,ACHE,APLP1,APP,ATM,BCHE,GFAP,MAP2,MAPT,NPY,ATXN1,SNCB,SNCA,SYP,UBC" Drug CID005315496 AC1NST48 Stitch 6.94E-04 1.00E+00 5.25E-03 5.98E-02 123 595 "AP2A1,AP1B1,OSBPL1A,ABCD2,ANK1,APLP1,DGKD,APP,DYNLL1,STX16,KIF1A,ADAM15,GPC2,CANX,ENTPD2,ENTPD6,AP4M1,LRBA,CDC42,CDR1,COPB2,CHGB,B4GALT6,COG1,CLTC,CNTN1,AKAP5,GAL3ST1,HAPLN1,VCAN,SDC3,SPOCK2,DCTN1,SPOCK3,DNM1,DNM2,RCAN1,DNM1L,EGFR,GOLGA7,STX2,CD320,F3,TUBB3,FCGRT,FGF1,ACTL6B,AGAP2,AGAP3,DCTN2,FOLR2,NBEA,NPTN,ERGIC3,AP4B1,B4GALNT1,JPH4,NEU3,GCNT2,ARFIP1,GJB1,GOLGB1,GRIA1,KIF3A,AP4S1,GABARAPL2,HMGCR,SMAP1,ITGAV,ITPKB,KCNC1,KCND2,KCNH2,KIF5A,LAMP2,MTTP,NEUROD1,OCRL,PCSK1,PCSK5,PCSK2,PDE1C,GPR85,ABCB1,PIK3C2A,SNX10,PLTP,PRKACB,MAPK3,RAB3A,RAB5B,PID1,ALG9,CLIP1,AP1AR,SCN2A,SMPD3,ST6GAL1,SYBU,ARFGAP1,SNAP25,BDP1,SPTB,STX1A,SULF2,NSFL1C,SYT4,EXOC7,WDR7,TF,AP4E1,TGFBR3,ACTR6,TPD52,SGK3,UBC,GORASP1,SLC30A3,SCG2,PLD4,GOPC,AP3B2,ST8SIA2" Drug CID000001951 AC1L1CLB Stitch 6.97E-04 1.00E+00 5.28E-03 6.00E-02 27 92 "ADORA2A,ANK2,SPTBN4,CAST,AP4M1,LRBA,DMPK,DYRK1A,B3GAT1,LOXL3,GRIA2,GRIN2C,GRIN2D,HTR2A,HTR5A,MAOB,MOBP,NRGN,TREM2,PDE1B,ABCB1,SMOX,PRKACB,SPTAN1,TAC1,TAC3,TACR1" Drug CID000146339 DAPs Stitch 6.97E-04 1.00E+00 5.28E-03 6.00E-02 27 92 "NR0B1,AQP4,SGCE,CACNA1A,CACNA1B,CACNA1E,DLGAP2,DLGAP1,DMD,DMPK,DPYSL2,DTNA,DTNB,EIF4G1,EIF4G2,DMTN,ATP8A2,MSTN,GK,HP,HPR,ITGA7,KCNJ10,NOS1,ENPP2,XPO1,SSPN" Drug CID000001143 neotrehalose Stitch 7.04E-04 1.00E+00 5.33E-03 6.06E-02 52 214 "ABHD6,APAF1,C5,CAPN3,CNR1,COL11A2,CS,HDAC9,DYNC1I1,ATN1,HIPK3,EN2,ENO2,PPP1R1B,FOXG1,ATP6V1H,GAA,DNER,GCK,GFAP,PPARGC1A,TCERG1,GPD1,GPD2,STON1,PTPN5,PACSIN2,HP,HPR,HSP90AA1,PACRG,MYH7,OGG1,PAH,CNTN3,PC,PENK,PFKP,ABCB1,PKM,PACSIN1,SNRK,PYGM,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SNCA,GANAB,UBC,JPH3" Drug CID000001263 AC1L1B35 Stitch 7.05E-04 1.00E+00 5.34E-03 6.07E-02 23 74 "ACHE,APLP1,APP,BCHE,SIRPA,CYP46A1,MAPT,MTR,NEFH,NTRK3,PKM,KLK6,RET,SP2,SP4,WWC1,TK2,TNFRSF1B,TPM1,TPM2,TPM3,TPM4,SMUG1" Drug CID000002798 clofilium Stitch 7.05E-04 1.00E+00 5.34E-03 6.07E-02 23 74 "ADRB2,HCN2,PNMA2,RBPJ,KCNA1,KCNA2,KCNA4,KCNA6,KCNB1,KCND1,KCND2,KCND3,KCNH1,KCNH2,KCNK1,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNK10,ENPP2,FXYD1,SLC12A2" Drug ctd:D002330 Carmustine CTD 7.08E-04 1.00E+00 5.36E-03 6.09E-02 103 485 "ACTN1,PLEKHG5,ADRA1B,AGT,ALAD,AMH,ANK2,CNTNAP1,KCNAB2,APC,VAT1L,ARNTL,ATP1A3,ADAM15,BMP7,BAIAP3,CALB2,PRC1,CDC25B,CHRM4,NGEF,COL9A1,CRYBB1,PITPNC1,ELMO1,ECM2,EDNRA,PHC2,SPEG,APC2,ETV1,EXTL1,F3,FECH,BAIAP2,FOXF2,CGREF1,FYN,GABRA2,GALNT15,NEK6,GFAP,GLRB,GP1BB,GPR37,ATXN2L,IGF1,KCNA4,KCND2,KCNH2,KIF5A,STMN1,MDM4,MGAT3,SCAMP5,MSR1,NBL1,NFE2L2,NFIX,NKX2-2,OGG1,PCDHGC3,PFKFB2,ABCB1,PIK3CD,ZNF655,SEPT4,MED1,MAPK10,PRPH,MASP1,RGR,RIT2,RORB,MEG3,STX1B,SCN8A,TNFRSF19,SFPQ,SHMT2,ST6GAL1,ST8SIA1,PKNOX2,SLC12A2,SLC14A1,SLC15A2,SLCO1A2,ZC3H13,SYP,TAC1,POPDC3,CUX2,ICAM5,NPL,SYNPO2,CADM1,UGT8,VGF,VLDLR,WIPF1,SF1,ZNF189,SLC30A3" Drug CID000000727 lindane Stitch 7.08E-04 1.00E+00 5.36E-03 6.10E-02 40 154 "ARSE,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CALM1,CBS,CCK,RGN,CS,PLCXD3,TOX,CHRDL1,DOCK2,ERBB2,EFS,FGFR3,FOXM1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,LYVE1,GPT2,PLCD4,TNFAIP8L3,HSD17B1,PLCB2,PLCD1,MAPK3,GSTCD,RYR1,RYR3,DDN,PLCB1" Drug 4819_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ACTN2,ADRA1B,SPARCL1,SEMA6A,GAS7,LDLRAD4,KRIT1,NEURL1,CLU,QKI,NECTIN3,ARMCX2,KIAA0753,SHANK1,EFNA3,RRAGB,FHL1,RND1,HRH3,ATXN2L,HLF,ICA1,IL6R,IL6ST,JAK2,MAN2A2,MAOB,MKLN1,NOS1,CDK18,CEP41,PRKAR1B,MAPK7,GRAMD1C,PTHLH,TCP11L1,IL17RB,ZFP30,PPP1R9A,CCDC88A,SLC11A1,MLC1,SMG6,AP4E1,TRPC1,FAM155A,XRCC4,NT5M,PLSCR4" Drug 3033_UP Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABAT,ACHE,AGT,NR0B1,BIN1,ANK3,ATP1A2,B3GALT2,KALRN,RUNX1T1,USP2,NRXN3,CNTN1,COL9A3,ARHGEF10,RIMS2,BRINP1,DCC,MFAP3L,TMCC2,EPB41,APC2,CEND1,CORO2B,TBR1,TMEM8B,GPD1,GSTM5,GPR45,HNMT,KCNC1,KCNJ5,KCNN3,MSR1,MYO6,NELL2,NRCAM,OPRL1,MAPK7,DCHS2,CNNM2,PTPN13,SOX15,MAPK8IP3,ACSBG1,RIMBP2,TRPC3,MAP3K12,AP3B2" Drug 6702_DN Niacin [59-67-6]; Down 200; 32.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "APP,SLC4A4,CBFA2T2,SYNGR3,CDC42,CLCN4,PDE4DIP,CNTNAP2,SGSM2,RABGAP1L,DPH1,CNNM1,EFNA3,EGFR,COQ7,DENND4A,B4GALNT1,COPS8,GLRB,MSL3,POLL,CNTRL,BACH2,IL6ST,DIPK1A,MMP16,PDE4D,RETREG1,PPARA,PPP3CC,PTCH1,PTN,PTPRE,C1orf54,MRPS18A,SCN8A,SCG5,ASAP3,FBXO11,SLC4A3,CAND2,UNC5B,BEX1,SPTAN1,THSD1,ARHGEF12,THRA,ZNF45,KCNAB1" Drug 4708_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASPHD1,ADORA2A,AK2,SEMA6A,BIN1,NUMB,CBFA2T2,ARHGEF2,TAOK2,AKAP7,LRIG1,ARHGEF10,SDC3,DCAF8,CTIF,BRINP1,JAKMIP2,MFAP3L,PLEKHO1,ST3GAL6,FHL1,SEMA4D,MSL3,GRM8,HNMT,INPP5B,KPNA5,LIG4,LMO2,NF1,NFYA,PRKAR1B,SEC14L1,ANKRD6,SLC15A2,BTBD7,SNCA,WDTC1,MAPK8IP3,ARC,ATP11A,SMG6,ZEB1,THRA,PARD3,VIPR2,ZNF74,DNALI1,EVI5" Drug 5984_UP Meticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG2,NR0B1,APP,CDC14B,PLA2G4C,MARK4,B3GALT2,NOL4,SCAPER,GYG2,CACNA1G,CACNB4,CDH2,TAOK2,DNAJB5,FAM149A,DMTN,ZIC4,ATP8A1,FHL1,GAP43,NEU3,PTGDR2,KCNJ5,KCNMA1,KCNN1,PLXNB1,GRAMD1C,PTPRD,RGS12,TTLL7,EMID1,KCNIP1,SCN8A,SH3BP2,ASAP3,SLA,SLC2A5,SLC8A1,SMARCD3,KIF13A,KDM4C,ACSBG1,TMOD1,LAT2,NT5M,ITM2C,WIPF2,TIGD6" Drug 502_UP sodium 4-phenylbutyrate; Up 200; 200uM; SKMEL5; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASCL1,DNAH17,NCOA1,ADGRB2,CH25H,ADGRG1,CHRM4,RAB28,CLTB,ARHGEF6,CNTFR,PDE4DIP,SGSM2,KAT8,FGFR1,FLNC,PNMA2,FYB1,GAD2,GPD2,PTPRT,SOX21,PADI2,IGF1,VWA5A,NAP1L1,NNAT,CCSER2,MBOAT7,RELN,RAP1GAP,RNASEL,SYNDIG1,ZNF331,SH3BP2,KIF16B,FAM214B,EFHD1,SMARCA4,SCN3B,ZC3H13,SPART,SST,NCDN,SYT11,TF,PLPPR2,MPPE1,LAS1L" Drug 2179_UP Graveoline [485-61-0]; Up 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BCAR3,TRMT9B,BIN1,ANK1,APC,GAS7,LDLRAD4,CFAP410,NMT2,CLOCK,CREM,AATK,VCAN,CNTNAP2,PPP6R2,EDRF1,SNPH,RIMS3,MYEF2,MFAP3L,SMG7,CD320,AGAP2,GPR153,FYB1,PCDH17,GRIN1,KCND1,KCND3,AFDN,P2RY1,PCSK2,PDGFRA,SH3BP2,CPEB3,SHANK2,SPTB,CDK19,ATP10B,ST5,STX1A,RALYL,ATP13A2,BHLHB9,TPM1,RUNDC3B,TRPC1,FAM155A,SLC13A3" Drug 405_UP tetraethylenepentamine pentahydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "RALGAPA1,RBM10,NDRG2,APBB2,GAS7,CADM3,CFAP410,HAP1,CAMK2G,SCARB1,CHGA,SLIT2,KIAA1549L,LY86,CNTFR,SPATA2,DPP6,DRP2,RCAN1,E2F5,EFNB3,SRPK3,FGFR1,DPYSL4,POMT1,GRB10,NR3C1,NNAT,OMG,OPCML,ENPP2,PMS2,RETREG2,PPP3CA,CEP41,PTPRN,C1orf109,RAD52,TCP11L1,SLC11A1,SNCA,KDM4B,ANKRD28,SEZ6L,TRIO,UBE3A,KCNAB1,MPPE1,AAAS" Drug 1603_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG3,C1QTNF1,PPFIA1,GAS7,ARNTL,BMP7,MTMR2,CD86,FOXN3,ARHGEF10,PPP1R16B,DTNA,EEF1D,SRPK3,BSCL2,PLEKHO1,ENO2,RASGRP2,RABEPK,VPS26C,EZH1,CAMSAP1,TRMO,SRCAP,PRDM5,MUM1,IDH3A,IL6R,MAP4,GIT1,NELL2,NTRK3,OMG,PDE4B,PTAFR,BCAN,FAM214B,SLC6A8,MAPKBP1,TMCC1,KDM4B,WDTC1,STX1A,TBL1X,EHBP1,TCF4,SMUG1,GDPD5,IFT88" Drug 2717_DN Ebselen [60940-34-3]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABAT,BRAP,KIDINS220,AMPD3,APBB2,APC,PPP4R4,ARRB1,CDK5R1,FUBP1,CAPN3,CLCN3,HOMER3,NRG2,USP6NL,CTIF,E2F5,SUGP2,ERCC2,ST3GAL6,CAMSAP1,KHDRBS3,CELF1,SEPT9,ALDH1L1,GPR75,RAB40B,GNG4,PADI2,MAP4,NNAT,NUMA1,CNTLN,RAB5B,SBF1,GALNT10,ANKRD6,ELMO2,MYH15,KDM4B,RBM26,ZC4H2,CAMSAP2,OBSL1,TK2,SH3GLB2,EVI5,UBE3B,NLRP3" Drug 3507_DN Tribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "AP2A2,PLA2G6,AMPD3,ARRB1,MARK4,ATP6V0A1,ADAM15,CFLAR,CDK5R1,GYG2,CFAP410,CACNA1D,SOCS6,PLAA,RAB26,NCOR1,PDE4DIP,GIT2,DBN1,LYPD1,TOM1,SIDT2,EFNA3,EGFR,COQ7,F3,KAT8,BAIAP2,TXNL4A,GPR37,MITF,ADAM22,NPTX1,PC,RETREG1,TNPO2,ZDHHC14,ROM1,SLC20A2,SLC22A4,RBM34,PHLDB1,ASTN2,PDLIM2,ZMYND8,ZKSCAN5,LMF1,ZNF24,UBE3B" Drug 1648_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BRAP,LTBP4,APOC1,CDC14B,ARNTL,ARRB2,ALDH4A1,ATM,MPDZ,BMP7,GYG2,KYAT1,CRY2,CSNK1E,CTNND2,RIMS3,DBN1,DBT,SGSM2,DSCAM,EFNA3,PCOLCE2,VPS26C,BAIAP2,SPIN1,RNFT2,ITPKB,KCNH2,MAP4,MPP2,NF1,APTX,GON4L,SH3BGR,PEX26,EPN2,BTBD7,SMARCD3,TSPYL2,MAPK8IP3,ELOVL4,JMJD6,KIAA0930,TCF7,BEX4,PARD3,LMF1,HPS4,SSPN" Drug 2642_DN Bisoprolol fumarate; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "AK2,BIN1,PPFIA3,CDC14B,ARHGDIG,MTMR2,QKI,DCAF8,GIT2,FBXL5,LYPD1,DSCAM,KAT8,BAIAP2,CAMSAP1,AGAP2,POLL,NR3C1,BTN2A1,HNMT,HSF2,GIT1,NFYA,CNOT4,SLC11A2,RETREG1,FSD1,PRKAR1B,NKAIN1,RAD51D,ZDHHC14,RGS3,ROBO1,ZNF821,ITSN1,ABLIM3,EMC1,ZBTB43,NXT2,FAM168A,MCF2L,TCF12,NSD1,TPD52,TPM1,ZMYND8,XRCC4,ZNF189,WNK1" Drug 5414_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG2,ALK,MRTFA,APBA2,APBB2,MARK4,AZGP1,CFLAR,MTMR3,CACNA1I,LDLRAD4,CBFA2T2,CDC42,EPS15L1,SULT4A1,GREB1,DTNA,EDNRA,EFNB3,SORBS3,COQ7,F5,CORO2B,DLC1,SORBS1,ALDH1L1,GLYR1,PCLO,NR3C1,RASSF8,ATXN2L,KCND3,KCNN1,LMO2,NAP1L3,NCAM1,NEFM,PDE3B,RETREG2,PPP5C,MAPK8,PTN,SATB1,LIMCH1,KIF21B,KIAA1107,UCHL1,MKRN3,WNK1" Drug 6791_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "RALGAPA1,ADRA1B,AMPD3,MARK4,ST3GAL5,BAIAP3,CA4,CACNB2,HAP1,NEURL1,CHRNA4,SULT4A1,CNTFR,RUSC2,EFNA3,REEP2,FHL1,FLNC,CNTRL,GRIA4,IRF8,MEF2C,MMP17,MOBP,ZNF862,MYT1,NPTX2,SLC25A23,POU6F1,CEP41,PRKAR1B,MAPK8,RAB3IL1,C1orf54,RFX2,EMID1,AMBRA1,CNKSR2,DZIP1,SLC1A7,FAM214B,SNCA,ZSWIM8,SPTB,PLCB1,TAL1,FAM189A1,PSD3,LAT2" Drug 3934_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1B,SEMA6A,ATP2B2,WHRN,CRY2,DCAF4,NOS1AP,TOX,USH1C,EDIL3,ERCC2,TUBB4A,PRELID3A,NSG1,NEU3,GFER,CSDC2,HPGDS,POLL,GNAO1,PTGDR2,ICA1,IL11RA,NCAM1,PCBP3,NTRK2,TREM2,ENPP2,CDIP1,PRKCB,GDPD2,SYNDIG1,ASIC4,CNKSR2,PDZD2,SOX2,SOX10,ZSWIM8,NMNAT2,JMJD6,TAC3,ATP11A,TCF4,DOCK9,HIF3A,THRA,TNS1,LILRA4,AP3B2" Drug 2676_DN LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG2,KIDINS220,AP2A2,MRTFA,TRMT9B,ANK3,APOC1,CACNA1G,TMEM184B,IQCK,NCOR2,ARHGAP32,SV2A,CDON,DYRK1A,E2F5,MBNL2,EIF4G2,ELN,MTSS1L,ERBB2,KIAA1109,FHL1,SEPT9,ALDH1L1,RUNDC3A,GPM6B,GRM8,KCND3,KHK,MAP4,MGAT3,NUMA1,MAPK7,SYTL2,ZCWPW1,KHDRBS2,ITSN1,FRMPD1,CCDC92,NLGN1,SOX2,ZCCHC24,ARHGAP26,MAPK8IP3,TNS2,XRCC4,ZNF142,TIGD6" Drug 6618_DN Protoveratrine A [143-57-7]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NME5,AMT,APBB2,CDK10,ALDH4A1,KSR1,ST3GAL5,SYNJ2,BTRC,WHRN,CSNK1E,DZIP3,AASS,SORBS3,PLEKHO1,ZNF549,SCARA3,C1orf61,ZNF44,TRAF3IP2,GLS,CNTRL,SHISAL1,IL11RA,INPP5B,MAN2A2,MAPT,MDM4,AFDN,NDUFA5,NF1,PC,SLC25A23,PTPA,GON4L,FAT4,BEND5,GSTCD,ATXN7,ZNF821,AMBRA1,ANKRD6,ELMO2,LHPP,TK2,TNS1,RPRM,NDRG4,SMIM8" Drug 6355_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADD1,APOC1,ATM,CFLAR,QKI,WHRN,SDC3,TOX,DBT,RABGAP1L,EDNRA,FEM1B,EPHA5,FCGRT,BAIAP2,FAM49B,USP19,GLS,MSL3,GNG4,PRRC2B,GPM6B,GUCY1B1,IL6ST,L1CAM,MATN3,MYO6,PC,SMOX,RC3H2,LRP12,MBOAT7,FSD1,CEP97,MYH14,FUZ,FAM214B,SHANK2,BTBD7,ZBTB43,DDN,SS18,TK2,TNS1,HIRA,NDRG4,SH3GLB2,MAP3K12,WIPF2" Drug 2400_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MTUS1,PLA2G6,MRTFA,NCOA1,ATP2B1,MTMR2,LDLRAD4,CAPN3,ZFYVE9,CPS1,MICAL2,OSBPL3,CST3,ZFYVE16,ZNF337,TBC1D5,CTIF,B3GAT3,E2F5,SORBS3,TNK2,RASGRP2,GPHN,VPS26C,ZNF589,ANKFY1,OGA,TRAF3IP2,GAD2,SEPT9,ALDH1L1,EML4,ITGA7,CNOT4,NLE1,ST8SIA5,ZSCAN32,RAB3IL1,RALGDS,FAM184A,RIC8B,GSTCD,TCP11L1,SLC15A2,SPTAN1,FAM168A,EXOC7,HIF3A,ZMYND8" Drug 2028_UP Azathioprine [446-86-6]; Up 200; 14.4uM; HL60; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,SEMA4G,MARK4,ASPH,AZGP1,CA12,CD86,CHN2,SULT4A1,CNTN1,AATK,DBN1,B3GAT3,HP1BP3,C2CD2L,SMG7,DSCAM,RCAN1,FRY,DMTN,FLNC,FYB1,SRCAP,OS9,CACFD1,FAM107A,ITIH2,NINJ2,NTRK3,OCRL,PDE4B,NLE1,SNRK,RGS12,CCDC25,ZFP30,SLC2A5,SLC20A2,ATP10B,ZC4H2,FCHO1,MLC1,TAC3,IQCE,FBXW11,CHST5,FIP1L1,SMIM8,ACTR3B" Drug 3995_UP Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "FZD9,ADRA1D,LTBP4,TRMT9B,OGT,B3GALT2,CADM3,NRP2,CACNA1G,LDLRAD4,CACNG1,SLC16A4,MAGI1,ADGRG1,TPP1,RGS6,DCT,SV2B,ETV1,F5,SRCAP,GNAO1,PRUNE2,KCNN1,KHK,MAP2,NCAM1,NPTX1,GPR173,NLE1,PPP1R1A,PPP2R2B,C1orf54,SUSD4,BEND5,RFX2,SLA,ZNF334,CXXC4,SNCA,SOX15,PLCB1,MCF2L,TEX15,TNS1,VIPR2,VSNL1,DPF3,JPH3" Drug 5359_UP Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "AGT,CDC14B,MARK4,CA12,CAMK2G,ARHGEF2,CHRNB2,EPS15L1,FAM189A2,AKAP7,C2CD2,SDC3,SMG7,ATN1,EGR3,FGFR1,FHL1,GAD2,GLYR1,CACFD1,HRH3,ATXN2L,INPP5B,KCND3,IPO5,VWA5A,MAP4,MBD1,MIA2,NOS1,OMG,KCNK10,GON4L,PTN,RGS10,NEK11,FOXRED2,SBF1,SLC1A7,EPN2,KDM4B,IQSEC2,ARC,TACR1,KIAA0930,THRA,TIAM1,FAM155A,EVI5" Drug 7234_UP Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "AK2,TRMT9B,AMH,APOC1,PLA2G4C,SLIT2,FAM189A2,MYRIP,HAPLN1,PLCH2,SPOCK3,ST8SIA3,CNNM1,EN2,RASGRP2,BAIAP2,PDLIM5,OGA,GAB1,SRCAP,POLL,GRM1,ELOVL5,ITPKB,LSS,MGAT3,NUMA1,PRKCB,MAPK10,PTHLH,PEX5,RASGRF1,SH3GL3,SYBU,PREX2,SLC2A5,FAIM2,KDM4C,IQSEC2,ANKRD12,MCF2L,TRIM2,CRTC1,ZNF34,RUNDC3B,TUBB1,VSNL1,WNK1,SEMA3B" Drug 7363_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BIN1,CDC42BPA,NRP2,DNAJB5,PICK1,NRG2,CSF1,TENM4,ABCC9,PLXNC1,OGA,GABRA5,SIGLEC8,CSDC2,GLI2,IRAK3,ARHGAP19,SHISAL1,IL11RA,IL12A,KCNC1,KIF5C,MMP16,NOVA1,PDE4D,EPN1,PMP2,PRKAR1B,FAM120C,TCP11L1,EMID1,SH3BP2,FUZ,NLGN1,KANSL3,BTBD7,RBM34,ZSWIM8,HECW1,PHLDB1,TCF4,CRTC1,SPX,SLC44A1,CABIN1,AMACR,KCNK12,KCNAB1,NUP214" Drug 2065_UP Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "TTYH1,C1QTNF1,ANK3,ADAM15,SYNJ2,MYRF,BAIAP3,RAB28,DNAJB5,USP6NL,TOX,CTIF,DBT,SPATA2,MFAP3L,DLG3,DPH1,DTNB,TOM1,HIPK3,EFNA3,TUBB4A,ZNF589,FGF1,TMEM8B,SRCAP,SYNPO,ICA1,LIG4,GIT1,PBX1,PPP5C,PRKAR1B,MAPK8,WDR25,PTHLH,RAB3IL1,PID1,SH3TC2,AMBRA1,SHANK2,ELMO2,KDM4C,UNC5B,DBNDD2,EXOC7,SSBP2,ZNF24,HPS4" Drug 7461_UP Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "LTBP4,BEGAIN,AMPD3,PLA2G4C,MARK4,SLC4A4,FGF17,SCAPER,SGCE,FOXN3,TPP1,AKAP5,CREM,ENTPD4,CRY2,MAML1,KBTBD11,TRAPPC9,DYRK1A,FAM198B,C1orf61,GAB1,GABRA5,SRCAP,MALT1,RAB30,GPR37,SPACA9,KLF12,MAP4,MAPT,MMP16,ADAM22,NEK1,NF1,SLC25A23,PLXNB1,POLG,RAD52,RPS6KA2,SEC14L1,SLA,SLC1A7,CXXC4,HECW1,THSD1,INKA2,THRA,KCTD2" Drug 1295_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MTUS1,BIN1,CDC42BPA,APP,BCL7A,LDLRAD4,CD86,CHN2,ARMC8,ARHGEF10,DAPK1,SPOCK2,SV2A,SGSM2,DTNA,ST8SIA3,CDHR1,FHL1,AFF2,OGA,SPIN1,GNG3,GPR19,MAP4K5,PADI2,INPP5B,ITGA7,MAP4,GIT1,NEFH,NEK1,NINJ2,MAPK3,MAPK8,PTAFR,PTCH1,TMEM231,RAP1GAP,RGS3,ZNF365,RAB3GAP1,SNCA,ATP11A,CAMSAP2,TK2,ICAM5,KCTD2,SMUG1,BEST1" Drug 3766_UP Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "DPF1,NDRG2,ADORA1,AP2A2,ATP2B2,SLC2A11,CFAP410,SYNGR3,CDO1,ADGRG1,CHI3L2,KIAA1549L,ABCC9,EFNB3,EIF4G2,ING4,RGS17,MTSS1L,ETV1,C1orf61,GPD1,GRM1,SOX21,IGFBP1,KCNB1,KCNN2,KIT,LMO1,AFDN,NTRK3,OPCML,PAH,EPN1,PILRA,PNMA8A,EMID1,RYR1,PPP4R3A,SLC11A1,SNCA,ZSWIM8,SLC19A3,CHST8,SLC44A1,TLR4,CHST5,RPRM,KCNAB1,GJC2" Drug 3440_DN Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1D,EPB41L5,FAM131A,MARK4,CA12,SCARB1,UBE2L6,VAX2,SLC4A7,SH2B1,CSNK1E,DBT,SMG7,DTNA,MRNIP,ANKMY1,FHL1,FAM49B,CNTRL,IL6ST,MAP4,MPP2,ADAM22,NPTX1,SLC25A23,STRN3,PRKAR1B,MAPK8,PRPH,CNNM2,ARHGEF10L,CCDC25,ABLIM3,SLC15A2,BTBD7,KDM4B,ZHX3,TSPYL2,CAMTA2,NCDN,DIP2A,STX1A,SEMA4A,EHBP1,NSD1,SLC44A1,CABIN1,CDK20,ZMYND8" Drug 3011_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "C3orf14,C1QTNF3,BIN1,ANK3,NCOA1,ADAM15,NRP2,SYNJ2,SLC16A4,SCARB1,ARHGEF10,ZNF337,CTIF,BRINP1,MBNL2,ABI2,AASS,C3orf18,EFCAB2,SIGLEC8,AHDC1,ADAM28,GNAS,LILRA2,GRK4,GSN,SLC2A6,MAP4,MGAT3,AFDN,NINJ2,SYTL2,PLPPR1,PTPRB,KHDRBS2,TMEM206,SYNDIG1,DDN,MAPK8IP3,TCF7L2,DOCK9,CDK20,TRO,BEST1,LMF1,XRCC4,SEMA3B,KCNAB1,PHTF2" Drug 326_UP rapamycin; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ACADM,ACTN1,AGT,C1QTNF1,SPOP,SYT13,ARNTL,NRP2,KRIT1,CBFA2T2,SLC4A7,HINFP,CTNND1,GPRASP1,JAKMIP2,ABI1,RASGRP1,MBNL2,TESK2,OLFM1,B4GALNT1,RAB40B,ICA1,KTN1,L1CAM,LAMP2,AFF1,ADAM22,PTOV1,NEK1,OMG,CCSER2,PLCD1,PACSIN1,PPM1B,MAPK10,BSDC1,KDM4B,TSNAXIP1,DBNDD2,LMO3,VPS13A,COBL,ANKRD28,CLASP1,TRIO,ZIC1,MAP3K12,MPPE1" Drug 5475_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MRTFA,BIN1,SPTBN4,AZGP1,CAMK2B,DLGAP2,GPR37L1,RCBTB2,TAOK2,AKAP6,SLC4A7,MYRIP,TBC1D5,HP1BP3,ABCC9,ELAVL2,STX2,CORO2B,ZNF589,OLFM1,FGFR1,FLNC,PRELID3A,C1QL1,GPM6B,TDRKH,GRM8,RASSF8,TJAP1,IPO5,LIG4,ADAM22,CNOT4,GPR85,RAD52,RGS12,RPS6KA2,SBF1,ZNF821,PPP1R9A,PKNOX2,SLC15A2,ZKSCAN3,ZC3H13,SYT5,SEMA4A,TCF7,MICAL1,ZNF711" Drug 5545_UP Isoflupredone acetate [338-98-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "CDC42BPA,APBA2,APBB2,APP,SEMA4G,PLA2G4C,ALDH7A1,SYNJ1,MTMR3,CAST,TPP1,CNN3,CNTFR,FAM149A,FEZ1,TBC1D5,KIAA0586,DAPK3,RABGAP1L,GNE,DTNA,NRN1,FGF13,FHL1,RUNDC3A,PCLO,HNMT,JAK2,KCNJ5,LIG4,MDM4,LRP1B,NFYA,NTRK2,PIK3CD,STRN3,FSD1,ELOVL2,SYNDIG1,SYBU,SLC2A5,SMTN,ROBO3,SEZ6L,CLIP2,XRCC4,ZNF24,HRASLS,NUP214" Drug 6002_DN Iobenguane sulfate; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "APBB2,FAM131A,ALDH4A1,BCL7A,SCAPER,C5,CBFA2T2,NMT2,CREM,PDE4DIP,FAM169A,CTH,DCAF8,MFAP3L,LYPD1,SGSM2,CDON,OPTN,DENND4A,VPS26C,ANKMY1,ACSL4,ZNF589,ATP2C1,GABRA2,GLS,MSL3,GRB10,LYRM9,NF1,SLC11A2,LRP12,PRODH,GON4L,FBXW7,ZNF821,ANKRD6,BTBD7,ZSWIM8,SPTAN1,TTBK2,TCF7L2,WDR7,AHCYL2,TFIP11,WNK1,GDPD5,PCBP4,MPPE1" Drug 6004_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASPHD1,ALCAM,TRMT9B,APBB2,ARRB1,ALDH7A1,ADAM23,MTMR2,CBFA2T2,ARHGAP33,ADGRG1,QKI,HOMER3,AKAP7,CNTNAP2,PPP6R2,EDRF1,DAPK3,OPTN,ACSL4,FECH,GABRA2,HNMT,IL6R,IL6ST,KCNJ3,IPO5,MAP4,MAPT,MEIS1,CNOT4,OGG1,LRP12,PRODH,FAM120C,RGS3,SAFB,MRAS,SMARCC2,ZHX3,NCDN,CEP68,TTBK2,MTCL1,PSD3,ARHGEF12,ZKSCAN5,PLPPR2,ZFP37" Drug 2270_DN Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,SEMA6A,MRTFA,AMPD3,FAM131A,RASL11B,ATM,ALDH7A1,GYG2,BTRC,RCBTB2,FOXN3,SLIT2,ZFYVE9,CNTN1,EDRF1,SMG7,PARD6A,KBTBD11,DSCAM,MBNL2,ACSL4,FGFR1,GLYR1,MSL3,GRIK5,GSN,ELOVL5,IL6ST,LIG4,TM6SF1,PDE3B,PLCD1,MAPK8,RAB3A,KLHDC8A,TCP11L1,SBF1,ZNF821,TRA2B,FBXO11,MAPKBP1,PLCB1,TACC1,TBL1X,AHCYL2,KAT6B,MPPE1,EPM2A" Drug 4228_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "TRMT9B,APBB2,APC,ADGRB2,LHX2,RAB26,ATN1,SGK2,SIDT2,EGFR,SORBS3,PLEKHO1,LRRC23,MTSS1L,ST3GAL6,DISC1,SEPT9,RUNDC3A,GPR75,LPAR4,GRM1,SCIN,KCNN1,KIF5C,MAPT,MBD1,AFF1,CNOT4,NPR2,NUCB1,PLXNB1,PTPRB,FRMPD1,SLC1A7,PPP4R3A,FAM214B,DOK5,UNC5B,IQSEC2,SS18,ATP11A,ZEB1,TRIM2,TNS2,TEX15,OSBP2,SPHK2,KCNAB1,PHTF2" Drug 6480_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADORA2A,MRTFA,CDK10,SLC4A4,CFLAR,MTMR2,BAIAP3,CA12,CACNA1D,SYNGR3,ARHGAP33,ABI3BP,LRIG1,PDE4DIP,ZNF804A,HP1BP3,EFNA3,F3,PRELID3A,INPP5K,GLS,GNG4,TDRKH,RASSF8,HNMT,MAPT,TM6SF1,LYRM9,NELL2,NFYA,NPTX1,SETD4,PTCH1,RGS3,RGS10,FBXW7,ZNF821,BCAN,NLGN1,SLC6A8,CXXC4,TROVE2,TACC1,PSD3,AHCYL2,CABIN1,PCBP4,EPM2A,SMIM8" Drug 6696_DN Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "CDC42BPA,CNTNAP1,APC,PPFIA3,ALDH7A1,ST3GAL5,CFAP410,SYNGR3,NRXN3,STOML1,PICK1,ARMCX2,SPATA2,MRNIP,AFF2,DPYSL4,FYB1,TRAF3IP2,GPM6B,INPP5B,KCNN1,MGAT3,NDUFA5,NF1,OPCML,PFKFB2,RETREG1,PLCD1,ZSCAN2,PID1,RAD52,ARHGEF10L,TRAPPC13,FAM102A,ASAP3,FBXO11,WDTC1,BEX1,WSCD1,DOCK9,TMEM121,TK2,HIRA,OSBP2,XRCC4,MAP3K12,KCNAB1,TIGD6,DPF3" Drug 6056_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "RALGAPA1,ASIC1,PLA2G6,ALCAM,APBA2,KCNAB2,APOC1,SEMA4G,RGS20,NUMB,ALDH4A1,SYNJ2,USP2,SEPT7,CDH10,SLC12A6,EDNRA,SORBS3,EN2,LRRC23,VPS26C,FHL1,DPYSL4,PDLIM5,FYB1,GLS,GRM1,HLF,KCNN2,SMAD1,MAP2,MMP16,NF1,NNAT,OXTR,SLC25A23,NKAIN1,RPS6KA2,ASAP3,SLN,AJAP1,VAMP1,ZEB1,TNS2,CRTC1,DICER1,TNS1,NPL,SMIM8" Drug 6682_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "RALGAPA1,ACHE,ADCY2,LTBP4,MRTFA,EPB41L5,AQP4,CFLAR,BAIAP3,CCNT1,TMEM257,ADGRG1,DNAJB5,CPS1,NCOR2,PDE4DIP,DLC1,FGFR1,EFCAB2,SRCAP,GSN,KLF12,VSIG4,ELOVL5,JAK2,KIT,ADAM22,MSR1,MYCN,NTRK2,CLDN11,PDE4A,PDE4B,PPP2R2B,MAPK8,GON4L,PTN,KHDRBS2,PNMA8A,TCP11L1,RASA3,FRMPD1,DOCK10,NTNG1,ZNF334,SNCA,ARHGAP26,ARC,TEX15" Drug 7171_UP Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "APBB2,CFLAR,AP4M1,ARHGEF10,PDE4DIP,HDAC4,DAPK3,MFAP3L,LYPD1,DTNA,SORBS3,EML1,MTSS1L,ERCC2,ACSL4,AGAP2,SEMA4D,DPYSL4,PRELID3A,ZNF44,SIGLEC8,MALT1,GLS,ATXN2L,NFYA,NUMA1,PCDH9,STRN3,POLG,PRKAR1B,PRPH,WDR25,WLS,ZFP30,PPP4R3A,WDTC1,EMC1,SPTAN1,IQSEC2,ZC4H2,JMJD6,PLCB1,ARC,ATP11A,SPX,TPM1,CDK20,AMACR,ZNF189" Drug 4593_DN Ethionamide [536-33-4]; Down 200; 24uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "APBB2,CDK10,CDK13,ADGRB2,CACNA1A,CBFA2T2,WHRN,PPP6R2,DLG3,CDON,EDIL3,EFNA3,SCML2,BAIAP2,OGA,USP19,PRRC2B,ELOVL5,DHX35,INPP5B,MAPT,SCAMP5,MT1M,PPP5C,GRAMD1C,PROX1,CNNM2,RIPOR1,RAB3A,PID1,CEP97,TCP11L1,MAPK12,ZNF821,DZIP1,ZNF334,ARHGAP26,VAMP1,ASTN2,CRTC1,TMEM121,SSBP2,VGF,VIPR2,LMF1,XRCC4,WNK1,EVI5,KAT6A" Drug 5539_UP Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BIN1,APBB2,PLA2G4C,ASPH,ALDH7A1,SCAPER,GYG2,AKAP6,BRINP1,SLC12A6,DSCAM,TOM1,EDIL3,TSPAN5,EDNRA,MTSS1L,NCALD,HPCAL4,FOXG1,FYB1,GAD2,GRIK5,DHX35,KCND3,ADAM22,ZNF862,NF1,CNOT4,NOVA2,ODF2,PLP1,C1orf54,KLHDC8A,TCP11L1,SCNN1D,MRAS,CNKSR2,SLC1A2,SLC6A8,TMCC1,SOX2,SPP1,BEX1,ATP10B,SYT11,PLCB1,NSD2,ZIC3,WNK1" Drug 7246_DN Etodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BIN1,APP,CFLAR,SYNJ2,HIP1R,CCNT1,REPS2,EPS15L1,SMARCAL1,CSNK1E,OSBPL3,SDC3,PPP6R2,USP6NL,DLC1,FHL1,EFCAB2,CINP,FAM49B,TRAF3IP2,GFER,HMGCR,DHX35,HSF2,IFI16,MIA2,NEK1,NFYA,RC3H2,TNPO2,ELOVL2,PTN,CASC3,CCDC88A,SMARCC2,DOP1A,SPATA7,KDM4C,SRPK2,COLGALT2,STX1A,VPS13A,EXOC7,FBXW11,KIAA0930,TK2,TNS1,TRPM2,PCBP4" Drug 4568_DN Sparteine (-) [90-39-1]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1D,C1QTNF1,KCNAB2,SYNJ2,MYRF,BTRC,CHM,CLCN4,QKI,SLC4A8,HAPLN1,ARHGEF10,SNPH,CNIH3,EXOG,LPAR6,MRNIP,ERCC2,EFEMP1,BAIAP2,FYB1,FYN,ZMYND11,SYNPO,INPP5B,JAK2,KIF5C,ARHGAP12,LSS,MT1M,PFKFB2,STRN3,GON4L,PID1,COA1,MYH15,KDM4B,TNIK,VAMP1,KIAA1107,IQCE,ARHGEF12,VIPR2,LAT2,XRCC4,MAP3K12,NT5M,PCBP4,PHTF2" Drug 2391_DN Nortriptyline hydrochloride [894-71-3]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG3,ALK,DOC2A,PPFIA1,SLC4A4,N4BP2L1,CFAP410,CAPN3,CAST,MAP7,CD86,ARHGAP33,IQCK,RCHY1,ARHGEF4,ZNF337,CTIF,DTNA,TSPAN5,EIF4G1,F5,ZNF589,SEMA4D,CINP,ZNF44,TRAF3IP2,GAD2,USP19,ZNF276,GLS,SPACA9,GRM1,ELOVL5,JAK2,MAP4,PFKFB2,NLE1,GTDC1,RGS10,SBF1,STUM,ANKRD6,WDTC1,ZBTB43,EXOC7,PLPPR2,VIPR2,NPDC1,URM1" Drug 1475_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "KIDINS220,MARK4,BCL7A,OSGIN2,FOXN3,LHX2,QKI,HOMER3,SLC4A7,SLC4A8,CTNND2,DCAF8,SIDT2,EFNA3,EPB41L1,ZNF589,DPYSL4,FAM49B,CGREF1,CSPG5,MALT1,COPS8,GNG4,TDRKH,HNMT,ITPKB,NPR2,PIK3R1,MBOAT7,MED1,ZCWPW1,MAP6D1,WLS,FOXRED2,ITSN1,ZKSCAN3,SMARCD3,KDM4B,WDTC1,ZHX3,ZNF423,TACC1,AHCYL2,ZNF34,TPM1,TRPC1,REEP1,PRDM2,GDPD5" Drug 606_UP (+/-)-thalidomide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADORA3,BIN1,APBB1,GAS7,ARRB2,SLC4A4,CACNA1A,ARHGAP33,TAOK2,NRXN1,ARHGEF6,PCYT1B,ARHGEF4,ECE2,ATN1,ING4,ELN,ETV1,RRAGB,STAU2,GAB1,SEPT9,GRM1,PADI2,KCNJ3,KCNQ2,NAP1L1,NAP1L2,NCAM1,SNTG1,PDE1C,PIK3CD,PPP2R2B,CCDC40,RNH1,FOXRED2,SLC8A1,WDTC1,DOK5,SP4,SPART,TMEM151B,TEX15,CDH22,TNS1,CA14,WIPF1,SPHK2,MAP3K12" Drug 6074_DN Anabasine [494-52-0]; Down 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABHD6,AP2A2,APP,CAPRIN2,CADM3,MTMR3,CA12,CNTN1,CRY2,CSF1R,RIMS2,TBC1D5,DAPK3,TMCC2,DTNA,DUSP9,HIPK3,FEM1B,MRNIP,C3orf18,ENO2,ZNF589,KIAA1109,GNAS,GNG4,GRB10,ITPKB,TM6SF1,PRKAR1B,PRPH,GON4L,NKAIN1,RAB3IL1,FAM184A,RGS10,ROM1,WLS,ZNF821,PEX26,SNCA,ST5,PLCB1,SYN2,MCF2L,PCDHA6,ZNF34,SLC44A1,TIAM1,PLPPR2" Drug 3687_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ARID1A,ADCY6,MRTFA,ALDH7A1,SCAPER,IL33,SYNGR3,PLEKHB1,LHX2,HOMER3,HAPLN1,NCOR2,DLG3,DPH1,DSCAM,FGF1,TRMO,CINP,TRAF3IP2,GAD2,ZMYND11,SRCAP,GNG4,GPR19,ITPKA,MAN2A2,MAPT,SCAMP5,ZNF862,NDUFA5,CNOT4,CLDN11,RETREG1,PTHLH,PTPRB,CCDC40,RGS10,SUPT20H,ASAP3,BTBD7,SLN,SYT11,KIAA1107,AMACR,WIPF1,WNT7A,XRCC4,MPPE1,GAN" Drug 2858_DN Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "AP2A2,SEMA6A,SRPX,KCNAB2,GYG2,CLGN,SOCS6,TAOK2,CLCN3,QKI,CTNND2,EDRF1,TBC1D5,GIT2,HIPK3,DMTN,ANKMY1,KAT8,ZNF589,FGFR1,FHL1,EFCAB2,SYT17,SRCAP,POLL,GPER1,MDM4,MIA2,PLEC,MINDY2,PRKAR1B,GON4L,RGS10,ZNF821,ZFP30,SYBU,BTBD7,ZSWIM8,EMC1,ARHGEF9,ASTN2,TACC1,EXOC7,TNS2,CRTC1,SLC44A1,TK2,WIPF1,SSPN" Drug 5103_UP Sulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MAP4K3,APC,BCAS1,SLC4A4,ADAM23,NRP2,ARHGAP33,SOCS6,CHN2,HOMER3,AKAP5,CRMP1,CSF1,DZIP3,DMPK,DTNA,COQ7,EPHB1,FGFR1,GPR19,GRM8,SOX21,NTRK2,RETREG1,MINDY2,PKN2,CNNM2,PTPRB,FAM120C,TMEM231,RAD52,RGS12,IL17RB,ZNF821,FBXO11,BTBD7,SOX2,GLT8D1,BEX1,ARHGAP26,MAPK8IP3,ASTN2,ATP11A,ARHGEF12,TPM2,VAV2,LAT2,NSD2,FZD3" Drug 2120_UP Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADORA2A,MRTFA,BEGAIN,BAIAP3,SYNGR3,RAB28,ABCG2,DNAJB5,COL9A2,CTNND2,PARD6A,EFNA3,LRRC23,MTSS1L,EZH1,HPCAL4,SORBS1,GAD2,DISC1,SRCAP,GRM1,SOX21,INPP5B,KIF5C,SMAD1,MAPT,CNOT4,NUMA1,PAK3,PDPK1,GPR85,RGS4,RGS10,ZNF821,ZFP30,SLC6A9,SMARCC2,SNCA,KDM4B,TSNAXIP1,TCF7L2,CHST8,CDK20,PRMT8,SPHK2,PRDM2,NT5M,SEMA3B,NUP214" Drug 6802_UP Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "PLA2G6,AMT,APBB2,ASCL1,ASPH,ALDH4A1,CFLAR,MTMR3,CA4,KCNAB3,ZFYVE9,DNAJB5,FAM149A,WHRN,CTH,GREB1,HDAC4,DBN1,DCT,DTNA,EFNB3,DMTN,CEND1,FYB1,SRCAP,GFER,GLYR1,ATF7,GRM1,IRAK3,IL6R,JAK2,LIG4,ZNF862,NPTX1,PCDHGC3,PFKFB2,CAMKV,ZSCAN2,TCP11L1,RPH3A,SLC11A1,KDM4B,ZSWIM8,SPTAN1,PLCB1,PSD3,CRTC1,KCNAB1" Drug 2966_UP Ioxaglic acid [59017-64-0]; Up 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "PLA2G6,MRTFA,BIN1,CDC42BPA,CDC14B,KIF1A,ZFYVE9,CLCN4,CLOCK,CSNK1E,SLITRK5,CTNND2,EDRF1,SMG7,FAM13A,LRRC23,CAMSAP1,FHL1,GAD2,GRM7,PADI2,IL6ST,MAP4,ADAM22,SAMD14,FXYD7,NRGN,PDE1B,PPP2R2B,PTAFR,RET,ROM1,MRAS,ST6GAL1,SLC1A7,LIMS2,BTBD7,SLN,TMCC1,ARHGAP26,SSTR2,INKA2,SEPT8,EXOC7,PDLIM2,SZT2,ZNF34,TPM1,UBTF" Drug 4687_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,AMT,RGS20,MARK4,NUMB,ALDH4A1,KIF1A,GYG2,SPAG9,SYNGR3,B4GALT6,AKAP7,ARHGEF4,DCAF8,DAPK3,CTIF,SMG7,PARD6A,MBNL2,AASS,PLEKHO1,STX2,ACSL4,FER,SEMA4D,CNTRL,RASSF8,ATXN2L,JAK2,MAP4,MAPT,NEUROD1,SERPINE2,MAPK7,TMEM260,RIPOR1,SH3BP2,PEX26,KIF13A,SS18,SMG6,TRIM2,TRIO,VIPR2,XRCC4,SF1,DNALI1,RNF170,SSPN" Drug 2539_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1D,AMPD3,ARRB1,SLC4A4,KIF1A,SLC16A4,SCARB1,KCNAB3,NMT2,HOMER3,ARHGEF10,CTIF,SPOCK3,DTNA,FCF1,EFNA3,SORBS3,RASGRP2,MTSS1L,VPS26C,KAT8,PDLIM5,GAA,INPP5K,ADAM28,TJAP1,MAP4,N6AMT1,MYT1,NF1,NNAT,NPR2,PIK3R1,RALGDS,RGS10,FRMPD1,BTBD7,SNCA,KAZN,EXOC7,DMXL2,TCF7,TCF7L2,TMOD1,RBFOX2,TRIO,FLRT2,PLPPR2,EMSY" Drug 3574_DN Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "PPFIA3,PPP4R4,PDXK,ALDH4A1,BTRC,CACNB2,TAOK2,SULT4A1,AKAP7,CRY2,ABCG1,DCAF8,DBN1,MFAP3L,DNM2,DSCAM,EIF4G2,MTSS1L,SEMA4D,USP21,INPP5K,HNMT,ICA1,ADAM22,PCDH9,LRP12,MBOAT7,PEX5,RAB3A,RAB3IL1,RAD52,SUSD4,GTDC1,NEK11,TCP11L1,EMID1,SH3BP2,CCDC88A,ZKSCAN3,EMC1,CAMTA2,NXT2,ARHGEF9,POPDC3,EXOC7,ZEB1,TGFBR3,THRA,CDK20" Drug 6256_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BIN1,PTCH2,NUMB,CFLAR,GYG2,CACNA1G,CACNA1D,ARHGEF2,SRSF11,QKI,CSF1R,SIPA1L1,ARHGEF4,CTIF,TMCC2,EGFR,LRRC23,FER,POLL,PCLO,GRIK5,HNMT,IL6ST,KCNH2,MAP4,PDE3B,RETREG1,PLCD1,RETREG2,MAPK7,GSTCD,UEVLD,RASA3,FNDC3A,SYBU,SLC15A2,SLC22A4,FAIM2,IQSEC2,TROVE2,PHLDB1,PLPPR2,LMF1,KCNK12,XRCC4,SPHK2,EVI5,KCNAB1,AP3B2" Drug 2315_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "SYN3,ADORA2A,GAS7,SEMA4G,ADAM15,CAMK2B,KCNAB3,LHX2,CLCN4,TPP1,SLC4A7,RASSF2,SPOCK2,JAKMIP2,DTNA,HIPK3,ELAVL2,ELAVL3,ELN,EN2,VPS13B,KCNMB2,ZNF589,FGF12,FGFR1,FHL1,FOXF2,GPR153,GLYR1,RASSF8,KLF12,ITPKA,BCO1,TAGLN3,NTRK3,OPCML,SERPINE2,PLCD1,PLTP,PACSIN1,MAPK10,PTH1R,ZSCAN2,SH3GL3,PKNOX2,CCDC88A,SLC9A5,ZNF423,VIPR2" Drug 3451_UP Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,C1QTNF3,AMT,CDC14B,ATP6V0A1,KSR1,CACNA1A,ARHGEF2,SRSF11,PICK1,SLC4A8,ENTPD4,NCOR1,ATRNL1,RIMS3,KBTBD11,DTNA,SCARA3,GABRG2,ADAM28,NR3C1,KCNA1,MAP4,MATK,TM6SF1,ZNF862,PCDH9,CDK18,PDE3B,PRKAR1B,PRODH,ZSCAN2,RAD52,GTDC1,TCP11L1,RPS6KA2,ASAP3,SMARCD3,VPS13A,SYT5,TGFBR3,CABIN1,VGF,VIPR2,VLDLR,WNK1,GDPD5,KCNAB1,MPPE1" Drug 7090_DN SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADD1,SRPX,BCAS1,APP,KIF1A,BCL7A,SCARB1,LHX2,FAM189A2,SLC4A7,FEZ1,PARD6A,RABGAP1L,RCAN1,DTNA,SIDT2,SORBS3,ING4,PDLIM5,ZNF276,TXNL4A,POLL,CACFD1,KHK,MAP4,MBD1,ADAM22,NCAM2,SETD4,PPP2R2B,RAB3A,RGS12,NEK11,TCP11L1,FERMT1,PEX26,EPN2,SHANK2,SMARCC2,SOX3,LHPP,TROVE2,ASTN2,PDLIM2,TBL1X,TP53BP2,PLPPR2,SEMA3B,URM1" Drug 6012_UP Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1D,LTBP4,CDK13,ATP1A2,CA4,CAMK2B,USP2,CACNA2D2,CHM,CSNK1E,PLCH2,PDE4DIP,RASSF2,SPOCK2,SLC12A6,DTNA,SIDT2,ING4,SRPK3,VPS13B,COQ7,RASGRP2,MTSS1L,FGFR3,HPCAL4,FOXG1,IQCG,GALC,GLS,KCND3,KCNN2,MID1,PFKFB2,PPP1R1A,PPP2R2B,GRAMD1C,ZDHHC14,KCTD17,TMEM206,WLS,RASA3,TACR1,SZT2,TMOD1,NPL,OSBP2,SCG2,MVB12B,SSPN" Drug 3615_UP Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "SYN3,AK2,SYT13,MRTFA,AMPH,BIN1,CAMK2B,CAST,NRXN3,CNN3,CPS1,CSF1,TENM4,ELMO1,TMCC2,EXOG,TRAPPC9,EN2,ERCC2,DCTN2,FAM49B,CSPG5,DENND2A,GAD2,HBS1L,HPGDS,GNAO1,SYNPO,INPP5B,ITIH2,KCNH2,KIFC3,LSS,CD200,NEUROD1,NTRK3,PTCH1,PTH1R,ELOVL2,ZFP2,STUM,SLC11A1,SLCO1A2,ZSWIM8,MAPK8IP3,VAMP1,CUX2,UBE3A,CA10" Drug 4081_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NME5,PLA2G6,ADGRF5,BCHE,NRP2,FUBP1,SCAPER,CA12,CACNA2D1,SCARB1,RAB33A,CLCN4,SULT4A1,CNTN1,ABCG1,SEC14L5,RIMS3,MAML1,DMPK,DTNA,EDIL3,EFNA3,PIPOX,CAMSAP1,PDLIM5,GPR17,MARK1,ADAM22,LYRM9,NF1,NTRK2,NTRK3,PDE2A,PRRX1,PTPRN2,CCDC40,RGS4,TMEM206,ZNF821,NTNG1,SLC1A2,RPH3A,KDM4B,TNIK,PLCB1,PCDHGA1,TNS1,CA14,KCNAB1" Drug 4649_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NME5,AMT,KCNAB2,CFLAR,CANX,LHX2,CLCN4,NCOR2,CSNK1E,VCAN,PDE4DIP,DCAF4,TBC1D5,RUSC2,EDNRA,FAM13A,PLEKHO1,BAIAP2,CAMKK2,INPP5K,POLL,GOLGB1,TDRKH,GRM1,TJAP1,NF1,PLCD1,SLC25A23,FSD1,PRKAR1B,GON4L,TMEM231,ROM1,SAFB,FNDC3A,ELMO2,SLC20A2,ERC1,SPTAN1,ELOVL4,ARHGEF12,BHLHB9,KCTD2,ZNF384,LMF1,WIPF1,HPS4,UBE3B,PHTF2" Drug 3047_UP Nizatidine [76963-41-2]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABHD6,SPARCL1,CCDC181,RGS9,FUBP1,CACNA1G,NRXN3,ABCG2,RAB26,RGS6,BRINP1,JAKMIP2,PARD6A,SLC12A6,PTK2B,ZNF589,CSPG5,SIGLEC8,SEPT9,GPD1,GPR45,KCNC1,MYH7,NPPA,OPCML,PDE1C,ABCB1,SMOX,PURG,PMP2,MAPK7,DCHS2,RGS4,RGS7,SEMA6D,LRRTM4,CNKSR2,FAIM2,SPTB,ACSBG1,SYT1,ASTN2,TACR1,ROBO3,FAM189A1,DICER1,TPM3,KLC2,SLC17A7" Drug 4008_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "TRMT9B,GAS7,APP,ASPH,CNOT8,NRXN3,DNAJB5,HOMER3,WHRN,SH2B1,CREB5,CSF1,ARHGEF10,ARHGAP24,ATN1,EFNA3,EGFR,MBNL2,AASS,ST3GAL6,CINP,ZNF276,LPAR4,GRM8,GUCY1A2,INPP5B,NUMA1,RETREG1,FA2H,FSD1,PPARA,MINDY2,PTPRB,FAM120C,MYH14,FRMPD1,SLC6A9,SLC9A5,SS18,TCF7L2,TRIM2,DNAH7,GPR161,TK2,TRIO,RPRM,XRCC4,KCNAB1,TIGD6" Drug 7518_DN DNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MTUS1,APAF1,PPP4R4,MARCH3,CFLAR,SYNGR3,ARHGEF2,MAGI1,ASIC3,RAB26,CNTFR,PDE4DIP,CNTNAP2,SLITRK5,SPOCK2,EXOG,ATN1,DUSP9,TUBD1,LRRC23,BAIAP2,C1orf61,ANKFY1,TRMO,DISC1,GART,GLYR1,CACFD1,KHK,MIA2,MX1,NPR2,PLXNB1,CDIP1,POLG,BTBD7,DDN,PLCB1,ASTN2,IQCE,TNS2,TNS1,ZMYND8,ZKSCAN5,VAV2,LAT2,XRCC4,MVB12B,RNF170" Drug 2092_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ARID1A,PPP4R4,SCAPER,CFAP410,CDH10,LARGE1,CLCN3,CLCN4,DNAJB5,AKAP5,HAPLN1,TENM4,CSF1R,C2CD2L,HS3ST2,ST8SIA3,SGK2,EGFR,TUBB4A,FGFR1,DLL3,SYT17,ALDH1L1,GLI2,GNG4,INPP5B,KIFC3,GIT1,ODF2,PALM,PDGFRA,PNMA3,MAPK7,CNTLN,PTHLH,RAD52,RALGDS,TRAPPC13,ANKRD6,SLC9A5,SLC20A2,ERC1,SPTB,TPM2,RUNDC3B,RPRM,WNK1,STMN4,HPS4" Drug 2732_DN Iopamidol [60166-93-0]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABHD6,BRAP,SLC12A5,ADRA1D,AP2A2,MTUS1,SRPX,FAM131A,ASPH,NUMB,FUBP1,EPS15L1,AKAP7,NRG2,SH2B1,DZIP3,PPP1R16B,DBN1,FCF1,TUBD1,PIPOX,F5,AGAP2,SEPT9,GPR75,EML4,GRM1,GRM7,TJAP1,KPNA5,MAP4,AFF1,MYT1,PCDH9,PLTP,MED1,PTAFR,ZSCAN32,ZCWPW1,SEC14L1,ZNF821,FAM102A,SLC11A1,DDN,LHPP,ADGRL3,TK2,CLIP2,MAP3K12" Drug 6826_DN Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "LTBP4,ATM,KIF1A,BTRC,CAMK2G,B4GALT6,TAOK2,ZFYVE9,FAM169A,SDC3,GIT2,DNAJC6,ING4,ANKMY1,EXTL2,FGF12,FGFR1,FGFR3,FHL1,SEMA4D,FAM49B,OGA,TXNL4A,TDRKH,MAP4,MBD1,KITLG,SCAMP5,PLEC,PLXNB1,RAB3IL1,RPS6KA2,SUPT20H,EPN2,BTBD7,SLC20A2,TTC17,SNCA,ZCCHC24,ZSWIM8,PHLDB1,JMJD6,ARC,KIAA0930,TCF7,PARD3,TRIO,MICAL1,GDPD5" Drug 7081_UP PHA-00846566E [724718-26-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BRAP,AK2,AMPD3,STX16,ALDH7A1,BMP7,GYG2,SGCE,CACNA1D,CAMK2B,CBFA2T2,SCARB1,ARMC8,PDE4DIP,NOS1AP,CTIF,FEM1B,EFNA3,EFNB3,ELAVL3,EFCAB2,PDLIM5,OGA,SRCAP,STON1,ATXN2L,IL6R,KCNJ3,MAP4,MMP17,GIT1,MX1,NNAT,PDPK1,PPP2R2B,PRPH,FAM184A,BSDC1,RGS10,FBXW7,SUPT20H,RAB3GAP1,SHANK2,IQSEC2,KAT6B,CABIN1,MICAL1,HPS4,ST7" Drug 2923_UP Moxonidine [75438-57-2]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "SYN3,KIDINS220,AMPD3,CDC42BPA,ANK2,MPDZ,KSR1,COL9A2,ABCG1,DAPK3,JAKMIP2,SORBS3,ELN,STX2,FGFR1,GPR153,GAD1,CPLX2,SRCAP,GNAL,GPM6B,GPR22,GRIN1,ATXN2L,ICA1,MEF2C,GIT1,ADAM22,NCAM1,NOS1,CNOT4,OPCML,OPRL1,NLE1,POU6F1,CEP41,PTPRN2,MYH14,TCP11L1,SEMA6D,RASA3,PREX2,FAM214B,SLC11A1,SNCA,TEX15,AMACR,VAV2,NUP214" Drug 3274_UP Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NME5,AMPD3,BIN1,OGT,CDC42BPA,ALDH7A1,CACNA1A,HAP1,CBFA2T2,CDH10,SOCS6,CHI3L2,ZFYVE9,CNTFR,ATRNL1,SPOCK2,RUSC2,DTNA,DYRK1A,PLXNC1,KCNMB2,NCALD,SPEG,SCML2,FGF12,FUT9,SIGLEC8,ADAM28,GNG4,GRB10,ITIH2,ITPKB,BCO1,NUMA1,EPN1,MTRF1L,MAPK7,C1orf54,KANSL3,ZCCHC24,PHLDB1,STX1A,SZT2,PCDHA5,CDK20,TPM2,VLDLR,GDPD5,ITM2C" Drug 6134_UP Ronidazole [7681-76-7]; Up 200; 20uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BCAR3,ATP2B2,ADGRB2,SYNJ2,MTMR3,MYRF,BTRC,HIP1R,CDH2,DNAJB5,SULT4A1,FAM149A,USP6NL,SV2B,DSCAM,EDIL3,EGR3,EIF1,GLRB,NXPH3,PTGDR2,KLF12,ICA1,TJAP1,KCND3,KCNJ5,MYT1,CLDN11,TREM2,PFKFB4,SERPINI1,PLTP,PTAFR,EMID1,RPS20,SYNDIG1,SLC9A5,SNAP25,PALLD,KDM4B,DOP1A,HECW1,DDN,EXOC7,WSCD1,TRPC1,LMF1,SPHK2,SLC17A7" Drug 603_DN nifedipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ACTN1,ADD2,BRAP,APBB2,ARNTL,MTMR2,CCK,CHRNB2,ENTPD4,SH2B1,TENM4,BRINP1,GIT2,DBT,DPP6,ACOT8,RCAN1,E2F5,SIDT2,EFNB3,ING4,LRRC23,KIAA1109,TMEM8B,GPD2,LILRA2,GRM1,NXPH3,AGBL5,KIFC3,NEK1,NELL2,PAK3,NLE1,MINDY2,PPP2R2B,LRRN3,RELN,RBBP6,SAFB,ZNF821,SLC11A1,RCOR3,IGSF9B,TMCC1,NMNAT2,TEX15,BHLHB9,TRIO" Drug 2257_DN Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "RALGAPA1,SRPX,MRTFA,BIN1,GAS7,DNAH17,RASL11B,ALDH4A1,BCL7A,CAMK2B,CAMK2G,ZFYVE9,SH2B1,MFAP3L,NR1D2,DTNA,EFNA3,PLXNC1,TNK2,RGS17,MSL3,GNG4,ELOVL5,MAP4,MAPT,MMP16,ZNF862,NUMA1,MINDY2,MAPK7,LRRC49,PTCH1,RIPOR1,RAB3IL1,ZNF821,ANKRD6,WDTC1,SZT2,TPM1,TRIO,RUNDC3B,VGF,KCNK12,SF1,ZIC3,WNK1,PRDM2,MPPE1,TIGD6" Drug 4506_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,AK2,APOC1,ADGRB2,CDK5R1,IL33,LHX2,LY86,AKAP7,HAPLN1,CSF1R,PDE4DIP,SGSM2,EDNRA,SGK2,TNK2,F3,SCML2,KIAA1109,FGF1,GAD2,SYT17,KCNMB4,GPR19,MAPT,TM6SF1,MMP16,PPARA,GRAMD1C,PTN,GAL3ST4,RGS10,CARF,NEK11,SELL,PPP4R3A,SLC9A5,UNC5B,DDN,ATP11A,EHBP1,TNS2,MICAL1,LMF1,ZNF24,WNK1,PRDM2,EPM2A,DPF3" Drug 961_DN 5253409; Down 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASPHD1,BRAP,EP400,APP,SYNJ2,MTMR3,AP4M1,LHX2,AKAP12,NCOR1,RIMS3,DNAJC6,G3BP2,ACOT8,EFEMP1,POLR1B,CGREF1,COPS8,GPER1,BRINP3,KCNJ3,KHK,MDM4,MMP16,NASP,NRGN,PCDH9,PDE3B,PIK3R1,POLG,GTDC1,SFPQ,NUBPL,KBTBD4,CDK5RAP2,MYCBP2,NXT2,VPS13A,TACC1,ANKRD12,TCF7L2,TRIM2,BHLHB9,KAT6B,ZMYND8,ZBTB14,PRDM10,MARCH8,PHTF2" Drug 5096_DN Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "MTUS1,BIN1,APBB2,APOC1,APP,KRIT1,ARHGEF2,TAOK2,STOML1,CREM,CNTNAP2,AK5,TRAPPC9,EDIL3,HIPK3,CNNM1,MBNL2,RGS17,STX2,DENND4A,SCML2,FGFR1,GLYR1,POLL,SHISAL1,IL6ST,JAK2,KCNN1,MX1,NUMA1,PDE4A,CDIP1,BCAS3,PEX5,PID1,RGS3,TCP11L1,SCN8A,ZFP30,LIMCH1,EMC1,BEX1,ELOVL4,ZNF34,CABIN1,ZNF24,ZNF225,UBE3B,SENP7" Drug 1509_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "SLC12A5,GAS7,SEMA4G,ASCL1,ATP2B2,SLC2A11,NRP2,CFLAR,SCAPER,QKI,AKAP6,CSF1,ARHGAP24,HDAC4,CDON,VPS13B,SPEG,FGFR1,GAD2,ADAMTS13,GRM8,GSTM5,GUCY1A1,ELOVL5,KCND3,KCNH2,KCNN1,KIFC3,VWA5A,MBP,MMP17,NNAT,NPPA,PALM,CDK14,CNTLN,PTN,RAB3IL1,RFX2,RFX3,BCAN,FAM214B,PKNOX2,SLN,SNAP25,ERC1,PLCB1,SYP,HIF3A" Drug 2050_UP Tamoxifen citrate [54965-24-1]; Up 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADRA1D,C1QTNF1,OGT,ANK3,BMP7,FUBP1,MYRF,SYNGR3,NMT2,HOMER3,CREM,VCAN,HDAC9,DBT,SMG7,EFNA3,PLXNC1,CDKL3,FOXG1,B4GALNT1,SRCAP,C1QL1,GLI2,GLYR1,GPR19,LPAR4,SHISAL1,KCNJ5,KIF5C,PDGFRA,GPR85,FA2H,POLG,MAPK8,PTCH1,SH3TC2,RGS4,SUGCT,MAPK12,SUPT20H,SNCA,TSNAXIP1,DDN,IQCE,ARHGEF12,AHCYL2,ZNF34,CBX5,NUP214" Drug 4531_DN alpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ASIC1,APC,ALDH4A1,RAB28,PLAA,DNAJB5,AATK,SNPH,MFAP3L,RUSC2,DMPK,TOM1,ETV1,STON1,GRK4,CNTRL,GRIK2,GRM1,SHISAL1,MPP2,MT1M,MX1,PBX1,PTPA,CNTLN,PEX5,RGS4,RGS10,ZNF821,ZFP30,AMBRA1,DZIP1,FAM214B,SCMH1,LIMCH1,ZNF415,IQSEC2,ZBTB43,MAPK8IP3,IQCE,CRTC1,DNAH7,PARD3,TNS1,TRIO,RPRM,WNT7A,ZBTB14,HPS4" Drug 1313_UP Carbarsone [121-59-5]; Up 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ABHD6,MTUS1,ARNTL,NUMB,MYRF,BTRC,CAPN3,KRIT1,CCNT1,SCARB1,CLGN,EPS15L1,BAG4,CREM,CSNK1E,PDE4DIP,SLITRK5,PPP1R16B,SPATA2,RUSC2,SGSM2,DTNA,PHC2,SUGP2,PTK2B,CELF1,SEPT9,ADAM28,RAB40B,SERPINE2,RC3H2,POU6F1,RELN,ZNF493,TRIM68,RNASEL,EXD2,SLC2A5,BTBD7,TMCC1,DOK5,SPTAN1,TROVE2,EXOC7,EHBP1,ZEB1,PARD3,RBFOX2,TRIM9" Drug 2184_DN Flurandrenolide [1524-88-5]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ACTN2,NDRG2,BRAP,PLA2G6,PPFIA4,APOC1,CAMK2G,INA,CD86,SCARB1,TAOK2,TMEM184B,IQCK,ZNF337,ING4,EIF1,LRRC23,F5,USP19,RAB40B,ICA1,IFI16,MEF2C,SCAMP5,MYT1,NFYA,SLC11A2,NUCB1,PLCB2,PLEC,PLP1,PILRA,MAPK7,SIDT1,RIPOR1,CEP97,ZCWPW1,RGS3,FBXW7,GALNT10,WDTC1,RAP1GAP2,ATP11A,KIAA1107,PLPPR2,LAT2,TRIM9,EVI5,PHTF2" Drug 1433_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; HL60; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BRAP,APBA2,APOC1,MARK4,CAPRIN2,BMP7,CAPN3,P2RX6,ARHGAP33,IQCK,SEC31B,AATK,ARHGEF10,ZNF337,HP1BP3,FAM13A,SORBS3,STX2,INPP5K,GDF9,GNG3,GPR12,ELOVL5,DHX35,ICA1,KCNA1,KCNN1,VWA5A,MYO7A,NTRK3,SERPINE2,ZSCAN32,ZFHX4,MYH14,CLIP1,ZNF821,ITSN1,NAXD,ZSWIM8,GANAB,MLC1,VAMP1,MGRN1,TCF7L2,RBFOX2,TSC2,SLC17A7,PCBP4,AAAS" Drug 7398_DN Merbromin [129-16-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "PPFIA3,CDK13,MAP7,CHM,AKAP7,ABI3BP,RCHY1,CSNK1E,PDE4DIP,PPP6R2,TBC1D5,SGSM2,DNM1,EGFR,LPAR6,TUBD1,EPB41L1,LRRC23,SPEG,TRMO,PDLIM5,FAM49B,FYN,ZMYND11,TMEM8B,DISC1,GPD2,DHX35,IL6ST,KIF5C,MAN2A2,MITF,NF1,PDE1C,SYTL2,RGS10,TCP11L1,RXRA,ATXN1,SCG5,ELMO2,SMARCA4,TMCC1,ERC1,SS18,EXOC7,SYNE1,TRIO,LMF1" Drug 389_DN wortmannin; Down 200; 0.01uM; HL60; HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ANK1,APBB2,APOC1,AQP6,CDC14B,ADAM23,CACNA1D,MAP7,CD86,ABCG2,CRHBP,RGS6,RCAN1,DTNA,EFNB3,FYN,HTATSF1,PCSK1N,FERMT2,KIF5A,LYRM9,OMG,OPCML,MED1,PRKAR1B,MAPK7,MAPK8,VPS13C,PTPRD,PYGM,RIPOR1,RALGDS,SUSD4,MORC4,RLBP1,MAPK12,SMTN,SLC11A1,ATP10B,PHLDB1,PLCB1,DNMBP,ARHGEF12,TJP1,CBX5,TRIO,KLC2,LMAN2L,AAAS" Drug 7330_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ADCY6,AP2A2,ALCAM,APOC1,MADD,CDK13,CFLAR,ST3GAL5,CA12,CREM,NCOR1,RIMS2,DBN1,TMCC2,DTNA,SIDT2,SORBS3,MFSD10,VPS26C,SEMA4D,INPP5K,MSL3,GRB10,LMO2,MAP4,NCAM2,NDUFA5,PCDH9,LRP12,PRKAR1B,PRPH,ELOVL2,RAB3IL1,GSTCD,SAFB,GALNT10,KDM4B,SS18,ATP11A,MCF2L,SZT2,TMEM121,CABIN1,VIPR2,DNALI1,HPS4,WIPF2,KAT6A,SSPN" Drug 583_UP HNMPA-(AM)3; Up 200; 5uM; PC3; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "SERPINA3,ABAT,NDRG2,KIAA1324,APBB2,APOC1,ARSF,MPDZ,BID,SLC25A14,MAP7,IQCK,ECE2,ATN1,DUSP9,USH1C,KCNMB2,PIPOX,OLFM1,DLL3,RAB30,GLS,GRK4,GRIA4,GRIK5,SOX21,NXPH3,ARHGAP19,ITIH2,MKLN1,CTNNA3,OGG1,PC,PRKAR1B,MAPK3,PTHLH,FAM214B,PKNOX2,KBTBD4,SPART,SSTR2,SYT11,PLCB1,TF,PARD3,CA14,TUB,CADM1,MPPE1" Drug 311_DN monastrol; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "NDRG2,ASCL1,CACNA1A,HAP1,CH25H,CDH8,B4GALT6,RAB33A,CLTB,ARHGEF6,DTNA,E2F5,TUBD1,CDKL3,CACNG2,AGAP2,GAB1,GABRA5,TRAF3IP2,GAD2,LILRA2,PTPRT,C2orf72,ITGAM,NOVA2,NPR2,NTRK3,OGG1,PTPRO,RGS4,SCNN1D,RPH3A,SHANK2,SPATA7,SPP1,ZC3H13,ZC4H2,SYN1,TACC1,KLHL4,TCF7,TMEM151B,TEK,TNS1,SEZ6L,TPD52,CDK20,VIPR2,NUP214" Drug 7547_DN Ald1.1-H_000455; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ALAD,CDK10,SYNJ2,SCAPER,KYAT1,PLEKHB1,TPP1,SULT4A1,HOMER3,NCOR2,PHF14,PPP6R2,SPOCK3,DLG4,ATN1,CNNM1,SIDT2,EGFR,RGS17,TRMO,SIGLEC8,INPP5K,COPS8,MSL3,JAK2,MAPT,MX1,NPR2,KCNK10,CCSER2,PTPRH,NEK11,SUPT20H,ZFP30,SH3GL2,FAM214B,SLC6A9,ZNF667,DDN,MAPK8IP3,ROBO3,ZEB1,RUNDC3B,UGT8,ZNF711,ZNF74,URM1,MVB12B,EPM2A" Drug 4068_DN Dibucaine [85-79-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "BIN1,CDC14B,ASPH,MAP7,KRIT1,TAOK2,CLCN4,NMT2,NIPBL,GIT2,SMG7,DLG3,EFNA3,EGFR,MBNL2,PLEKHO1,DENND4A,CDKL3,RRAGB,ATP8A1,ZNF589,TRMO,ATP2C1,DENND2A,DISC1,SRCAP,GNAS,ARHGAP19,SHISAL1,TJAP1,IL6ST,LRP12,MSANTD2,RPS6KA2,SH3BP2,SMTN,ELMO2,EMC1,RGL1,FAM168A,ARHGEF9,EXOC7,ZEB1,SIK3,TIAM1,ZNF45,MPPE1,ST7,KAT6A" Drug 496_UP iloprost; Up 200; 1uM; SKMEL5; HG-U133A Broad Institute CMAP Up 7.22E-04 1.00E+00 5.38E-03 6.12E-02 49 199 "ACADM,ABHD6,ALK,AMT,APOC1,ASCL1,RGS11,MTMR3,CHRM4,DNAJB5,ARHGEF6,DLG3,SEZ6L2,SUGP2,KCNMB2,EYA1,ACSL4,ZNF589,ATP2C1,OGA,USP19,LILRA2,GRIA4,NXPH3,KCNC1,AFF1,NACA,NPTX1,GPSM2,C11orf49,NUDT11,TCP11L1,ASRGL1,FBXO11,SLC1A3,MAPKBP1,ZSWIM8,SPTB,SPART,LMO3,ZFR2,CBX5,KAT6B,TNNT1,SEZ6L,TST,FLRT1,ZNF32,NUP214" Drug 6516_DN Tiletamine hydrochloride; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,ABHD6,FAM131A,BCAS1,SLC4A4,CFLAR,BTRC,CBFA2T2,TAOK2,SIPA1L1,DZIP3,RIMS3,GIT2,DBN1,KIAA0753,CNNM1,EGFR,COQ7,LRRC23,STX2,C1orf61,INPP5K,MALT1,CNTRL,GRIK5,BTN2A1,RNFT2,HNMT,LMO2,MITF,LYRM9,OGDH,NKAIN1,FOXRED2,ZC3H13,ZBTB43,SS18,ASTN2,MTCL1,EXOC7,PSD3,CHST8,CABIN1,CDK20,HIRA,EMSY,GDPD5,RNF146" Drug 3968_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,AK2,APBA2,CDC14B,PPP4R4,ATM,SCAPER,CACNA1D,ARHGEF2,RAB28,CPS1,CNTNAP2,RIMS2,CYBB,TMCC2,CDON,DRD1,ATN1,MRNIP,LRRC23,KIAA1109,FGFR3,FHL1,FAM49B,GAD2,GCNT2,GNG4,GPM6B,GPER1,GPR37,GSTM5,INPP5B,KCNK2,KCNMA1,SMAD1,MMP16,ADAM22,PDE1C,PDE4A,PFKFB2,RAB3IL1,SEMA6D,NLGN1,PREX2,FAM214B,ATP10B,UCHL1,EMSY" Drug 6964_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "AK2,CDC42BPA,ADAM15,SYNJ2,CCNT1,CNOT8,RAB28,HOMER3,CHD1L,CREM,SOCS5,DCAF8,C2CD2L,SMG7,MRNIP,VPS26C,F8,PDLIM5,TRAF3IP2,INPP5K,GPD2,RNFT2,HSF2,NEK1,NFYA,CCSER2,RETREG1,KCTD15,SLC25A23,FSD1,PPP2R5C,CCDC25,TRAPPC13,AMBRA1,SOX3,TSPYL2,SS18,ARHGEF9,EXOC7,SATB2,ARHGEF12,BHLHB9,RBFOX2,SSBP2,SF1,MAP3K12,RNF170,GAN" Drug 2412_UP Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ABAT,ACTN2,ANK3,SLC4A4,ADGRB1,USP2,DCAF4,SEC14L5,DBT,DSCAM,USH1C,FCF1,DMTN,LRRC23,CAMSAP1,GABRA4,ERAP1,POLL,TJAP1,KCNN1,KHK,LSS,MID1,ADAM22,NAP1L2,NEK1,NPPA,NTRK2,PDE1C,PDE4B,PHKG1,PTAFR,SCN2B,GALNT10,ASAP3,SYBU,EPN2,BTBD7,SLC20A2,SOX2,TROVE2,PDLIM2,TBL1X,TCF7L2,TEX15,DNAH7,TRPS1,SPHK2" Drug 2485_DN "Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,NDRG2,ANK2,ARRB1,ATP2A2,ADAM23,SYNJ2,CACNB2,CAPN3,CBR1,CLCN4,STOML1,C2CD2,CSNK1E,CTH,HDAC9,TM9SF4,CTIF,DTNA,EFNA3,PCOLCE2,KAT8,CSPG5,SEPT9,INPP5K,GRB10,LSS,MAP4,P2RX7,TRHDE,PTCH1,TMEM231,RAB3IL1,RAD51D,RAD52,RNASEL,SEC14L1,SLC11A1,ZNF667,EMC1,RAP1GAP2,DDN,SEPT8,KAZN,TNS1,RBFOX2,ATP6V0E2,URM1" Drug 3404_UP Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "NDRG2,BRAP,APBB2,APOC1,PPFIA3,ARHGDIG,PDE8B,BTRC,PCYT1B,SNCAIP,HDAC4,SGSM2,TOM1,VPS13B,FHL1,SCARA3,GAD1,HBS1L,ALDH1L1,SPACA9,KCNJ3,LMO2,KITLG,NTRK3,PIK3CD,PLPPR1,ZSCAN32,GSTCD,TCP11L1,PREX2,SHANK2,LIMCH1,RBM34,ZNF423,ZBTB43,SPART,CLSTN2,ST5,PHLDB1,MTCL1,ARHGEF12,TRPC1,VGF,ZFP37,REEP1,MPPE1,MARCH8,SSPN" Drug 6811_DN Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "RALGAPA1,APBB2,GAS7,PDXK,MARK4,CFLAR,ST3GAL5,BTRC,FOXN3,B4GALT6,TAOK2,ZFYVE9,RIMS2,SLC12A6,SIDT2,RRAGB,ZNF589,DPYSL4,POLL,GSN,MAP4,PCDH9,TNPO2,MED1,PPP2R5C,PRODH,RAB3A,RGS3,RGS10,NEK11,RPS6KA2,SH3BP2,SMTN,SLC9A5,SNCA,ZCCHC24,ZHX3,CEP68,STX1A,KIAA0930,AHCYL2,TMEM121,CHST8,SLC44A1,TK2,PARD3,WNK1,AAAS" Drug 3522_DN Imidurea [39236-46-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ADD1,BIN1,CDC42BPA,CDK13,RASL11B,KIF1A,CFLAR,CAMK2G,ABI3BP,CSF1,LRIG1,DZIP3,MFAP3L,LYPD1,SMG7,KBTBD11,MED12,PHF20L1,SUGP2,MBNL2,SCML2,DPYSL4,SEPT9,TDRKH,HNMT,HSD17B1,KCNH2,KIF2A,MEIS1,ADAM22,LYRM9,NEK1,MBOAT7,PPP5C,CEP97,RAD52,RALGDS,RGS10,ZFP30,SLC20A2,ZHX3,SPTAN1,ZNF34,ZMYND8,MICAL1,LMF1,SEMA3B,SMIM8" Drug 1610_UP Ascorbic acid [50-81-7]; Up 200; 22.4uM; HL60; HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "KIDINS220,ALAD,ARNTL,EIF4G3,CFLAR,ARHGAP33,FOXN3,PLAA,CLCN3,QKI,CHD1L,SEC31B,CSF1,CTH,DBN1,DBT,C2CD2L,SIDT2,ABI2,ZNF589,SMC2,PDLIM5,OGA,FYB1,GABRA4,ZNF638,NXPH3,IL6R,MAP4,MPP2,NPPA,OMG,GPSM2,STRN3,POLG,BCAN,FAM214B,ARHGEF40,ZC3H13,CDK19,TTBK2,PRRC2C,KAZN,MCF2L,TK2,ZKSCAN5,CADM1,ST7" Drug 3021_UP Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "NDRG2,ADCY2,MTUS1,CDC42BPA,APOC1,PLA2G4C,CCDC181,NRP2,CAPN3,CBFA2T2,TMEM257,GPR37L1,PDE4DIP,ZEB2,RUSC2,NR1D2,EFNB3,EGR3,ING4,ELN,RASGRP2,ZNF549,ATP8A1,STON1,SCIN,KCNK1,PACRG,MAG,MBNL1,MMP16,MSR1,SLC11A2,OMG,PDE4A,ENPP2,PTH1R,SGK1,SLC1A3,SPP1,LHPP,TAL1,AP4E1,SEZ6L,TPM3,SSBP2,UBE3A,WNT7A,SCG2" Drug 3193_DN Mebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASPHD1,LTBP4,MRTFA,DNAH17,MARK4,ALDH4A1,ATP6V0A1,CFLAR,TAOK2,FAM189A2,HOMER3,PDE4DIP,CTIF,RABGAP1L,HSD17B14,KAT8,FYN,POLL,GNG4,GOLGB1,GRB10,HNMT,KCNH2,MEIS1,NEK1,CNOT4,CAMKV,SLC25A23,POLG,RGS12,FNDC3A,SLC1A7,SMTN,SLC20A2,RBM34,ZBTB43,ST5,ELOVL4,TACC1,ANKRD12,EXOC7,PCDHA5,THRA,TPD52,ZKSCAN5,EVI5,HPS4,TIGD6" Drug 5342_UP Carbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,ABHD6,AP2A2,SEMA6A,ALK,APC,EPB41L5,ATM,CFLAR,ST3GAL5,CACNA1I,CACNB2,FOXN3,CLCN3,CRY2,PPP6R2,HDAC4,ZNF589,FER,ANKFY1,SORBS1,OGA,SEPT9,GRB10,KCNN1,MAP4,ZNF862,NOS1,NPR2,PC,GON4L,PEX5,ROM1,KCNIP1,ITSN1,SLC6A8,SLC9A5,BTBD7,ZKSCAN3,ZHX3,UNC5B,PLCB1,MCF2L,TCF7L2,PCDHA6,VAV2,KCNK12,GDPD5" Drug 5525_UP Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "DPF1,ADCY6,BIN1,CDC42BPA,ANK1,SEMA7A,BACH1,CFLAR,USP2,QKI,CNR1,NCAN,CNTNAP2,SNPH,RASSF2,HP1BP3,RABGAP1L,MED12,EDIL3,RCAN2,REEP2,TUBB4A,FGF1,FGFR1,BAIAP2,SCARA3,GAB1,ZNF44,POLL,SYNPO,ITIH2,KCNB1,ADAM22,MX1,NOVA1,PLXNB1,PPARA,DIRAS2,ZSCAN32,RALGDS,GTDC1,SH3BP2,ZBTB43,KAZN,PSD3,TRPC3,KCNK12,SEMA3B" Drug 4848_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,ARID1A,ADRA1D,PLA2G6,SEMA6A,APLP1,FAM131A,ARRB1,MARK4,ATP6V0A1,SCAPER,CRLF1,CACNA2D2,FAM189A2,FAM169A,DAPK3,JAKMIP2,HSD17B14,MTSS1L,ERCC2,FGFR1,TXNL4A,PCLO,DHX35,IGSF1,KCNN2,VWA5A,MIA2,NF1,CNOT4,NUCB1,RETREG1,SAMD9,RGS10,KCTD17,ASAP3,PREX2,WDTC1,CDK19,TSPYL2,SS18,RGL1,PHLDB1,KAZN,AHCYL2,ZNF34,TMOD1,CADM1" Drug 3627_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ACTN2,AP2A2,NME5,LTBP4,BIN1,KCNAB2,APLP1,PLA2G4C,ATM,SLC4A4,CFLAR,BAIAP3,LDLRAD4,SLIT2,CRY2,PDE4DIP,SLC12A6,FAM49B,ZNF44,GPER1,SLC2A6,MAP4,MIA2,MMP17,PLCD1,SMIM7,PRKAR1B,PRKCB,MAPK10,CNNM2,ZSCAN2,MYH14,KCNIP1,ZNF821,RPH3A,FAM214B,DOK5,IQSEC2,CLSTN2,SUPT5H,VPS13A,EXOC7,KIAA1107,TBCEL,CRTC1,CHST8,PARD3,MICAL1" Drug 2114_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ADORA2A,MRTFA,KCNAB2,APC,ALDH4A1,ATP2B2,ADGRB2,CCNT1,CDH8,PICK1,DBT,CELSR3,MTSS1L,EZH1,KIAA1109,DCTN2,DLL3,DISC1,SRCAP,SPIN1,GLYR1,GNAL,GNG3,GNG4,TPPP,INPP5B,KIF5C,SMAD1,GIT1,MT1M,SLCO1C1,CNOT4,OPRL1,PAK3,PDE4B,MAPK7,PTPRH,RGS4,ZBTB43,INKA2,TBL1X,SYNE1,TPM1,HIRA,EMSY,PRDM2,SEMA3B,SLC17A7" Drug 2076_UP Nocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "BRAP,GRAMD1B,PLA2G6,ANK3,APBB1,ALDH4A1,KIF1A,C5,MYRF,SYNGR3,ARHGAP22,LHX2,STOML1,NIPBL,ARMC8,FAM149A,AATK,CSF1,SMG7,SUGP2,MRNIP,CDKL3,FGF1,SEPT9,SRCAP,C1QL1,DBF4,GPM6A,STON1,GIT1,ADAM22,PAK3,PALM,SMOX,SMIM7,FSD1,BEND5,SMARCD3,MYH15,LHPP,VAMP1,ASTN2,ATP11A,CBX5,SEZ6L,TPM2,ZMYND8,MARCH8" Drug 7442_UP Acemetacin [53164-05-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "LTBP4,MRTFA,APAF1,SEMA4G,SYNJ2,GYG2,CACNA1D,ARHGEF6,SDC3,RIMS2,PPP6R2,GIT2,DNAJC6,DLG3,DNM1,ATN1,DTNA,TOM1,MBNL2,COQ7,ZNF589,BAIAP2,PRKAG2,FAM49B,SYT17,POLL,GRIN1,ELOVL5,AGBL5,INPP1,ZNF862,MYT1,SETD4,PTCH1,RAB3IL1,RNASEL,RPS6KA2,SH3BP2,EPN2,LIMS2,SLC22A4,PLCB1,EXOC7,KIAA0930,MAP3K12,MPPE1,PHTF2,SSPN" Drug 4361_DN Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "AP2A2,MTUS1,AK2,SEMA6A,ADAM15,SYNJ2,CDC27,FAM169A,DAPK3,SMG7,NR1D2,TSPAN5,EIF4G1,COQ7,ERCC2,NCALD,AGAP2,SPIN1,GLYR1,STON1,IL6ST,INPP5B,MAP4,MMP16,ZNF862,NEK1,NOS1,NUMA1,PIK3R1,MED1,GRAMD1C,ATG16L1,SLC25A36,SEC14L1,SH3BP2,SON,ZBTB43,PRRC2C,TBL1X,KIAA0930,TCF7L2,WASHC4,DICER1,USP1,PLPPR2,ZNF24,ZBTB38,SNX27" Drug 1783_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ADORA1,EIF4G3,BCL7A,CA12,HAP1,SLIT2,COL9A2,PPP6R2,SPOCK2,C2CD2L,RASGRP2,FCGRT,BAIAP2,ALDH1L1,LILRA2,GRM1,VSIG4,ITGAM,LAMA2,MAP4,GIT1,MX1,MYO7A,NELL2,NUCB1,OGG1,OLR1,PALM,PACSIN1,ELOVL2,RGS12,RNASE1,ITSN1,NTNG1,CLSTN1,SMARCA4,KDM4B,FCHO1,STX1A,MLC1,KIAA0930,ARHGEF12,ICAM5,TNS1,TRPM2,SF1,URM1,WIPF2" Drug 5732_DN Sulfameter [651-06-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "MTUS1,MARK4,SCAPER,LARGE1,FOXN3,CHM,CHN2,TAOK2,CREB5,GIT2,MFAP3L,SMG7,EDNRA,EML1,EPHA5,TAOK3,SCML2,FGF13,SCARA3,KIF2A,CNOT4,PLCD1,STRN3,MAPK3,PTN,TMEM231,RAB3A,ATG16L1,RAP1GAP,RPS6KA2,RXRA,SAFB,MAPK12,TMCC1,MAPK8IP3,VAMP1,ATP11A,FBXW11,CRTC1,ATP13A2,ZMAT3,ZNF34,CABIN1,HIRA,VGF,XRCC4,SH3GLB2,MAP3K12" Drug 2459_DN Nitrofural [59-87-0]; Down 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "RALGAPA1,ADRB2,KIDINS220,AMH,AMPD3,BIN1,APAF1,APOC1,NCOA1,SCAPER,LDLRAD4,SCARB1,COL9A2,PDE4DIP,DGKG,MAGI2,CNNM1,EFNB3,TNK2,C3orf18,FOXG1,GABRA2,MSL3,IL6ST,JAK2,LSS,MDM4,NAP1L2,NF1,NUMA1,OGG1,MAPK10,RAD52,SMTN,CAND2,TROVE2,ADGRL3,KIAA1107,TBCEL,TCF7,TNS2,CRTC1,ICAM5,FLRT2,BEST1,XRCC4,ZFP37,NLRP3" Drug 5620_DN Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ARID1A,NDRG2,BIN1,SCAPER,GYG2,CAMK2G,CDH8,CLGN,CHRNB2,SLIT2,SULT4A1,NRG2,SH2B1,CSF1R,EFNA3,EFNB3,EIF4G2,LRRC23,FER,KIAA1109,FOXG1,AFF2,GPR153,OGA,GAB1,GCNT2,SRCAP,RNFT2,RASSF8,HNMT,KCNJ3,MPP2,NEUROD1,NF1,EPN1,SAMD9,ELOVL2,FAM184A,RGS12,ZNF821,FAM214B,CLSTN2,MAPK8IP3,SEMA4A,SZT2,PSD3,SYNC,SLC17A7" Drug 4804_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASPHD1,ASIC1,ABHD6,AP2A2,LTBP4,DGKD,CDC14B,ARRB2,PDE8B,CFLAR,MTMR3,HAP1,SPAG9,ARHGAP33,LHX2,ABCG1,SDC3,ARHGEF4,DCTN1,ZNF804A,HP1BP3,RCAN1,DTNA,ENO2,MSL3,GNG3,GOLGB1,PRRC2B,DHX35,KHK,IPO5,AFDN,NRGN,NUCB1,PLEC,SAMD9,RIPOR1,KCTD17,FUZ,SMTN,KIF13A,LHPP,PHLDB1,ZNF34,SLC44A1,KCTD2,NSD2,NDRG4" Drug 3422_UP Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "DPF1,ALK,APBB2,PPFIA3,CDK13,ATM,ATP6V0A1,CFLAR,CACNA1D,GREB1,SNPH,DAPK3,CNIH3,RUSC2,DTNA,C3orf18,OGA,GAB1,GFER,GLYR1,GNG4,LPAR4,KHK,IPO5,MAOB,MBD1,NELL2,P2RX7,TMEM104,RAB3A,RAB3IL1,RAD52,SH3TC2,ZDHHC14,TCP11L1,EMID1,WLS,ASAP3,SMTN,BTBD7,CEP68,PLCB1,CRTC1,UBTF,PLPPR2,VIPR2,VLDLR,KCNAB1" Drug 7497_DN CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "NDRG2,ADD2,SEMA4G,BACH1,SCAPER,CA4,CACNA1D,KALRN,KCNAB3,QKI,FEZ1,MICAL2,EDRF1,SNX29,HIPK3,PLXNC1,SORBS3,FGFR1,FHL1,FLNC,TRMO,TXNL4A,CRCP,GLYR1,GNG3,GNG4,PRDM5,MAP4K5,HSF2,IL6R,INPP5B,ITIH2,OPRL1,MBOAT7,DCUN1D2,GSTCD,PKNOX2,SMARCD3,WDTC1,INKA2,PLCB1,ANKRD12,DOCK9,TPD52,SLC30A4,EPM2A,SMIM8,RNF170" Drug 4325_DN Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "KIDINS220,AP2A2,APLP1,ALDH4A1,ADGRB2,CDK5R1,ARHGAP33,PLEKHB1,B4GALT6,NRG2,HAPLN1,CSF1,SLITRK5,DTNA,SORBS3,EN2,ETV1,FGFR1,SCARA3,SORBS1,CINP,GLRB,GUCY1B1,ITPKB,KHK,MAPT,MDFI,MEF2C,NDP,NFIX,PTPA,PRKAR1B,MAPK7,ZDHHC14,ZC3H14,PAQR6,SFPQ,SH3BP2,BEX1,ATP11A,TBCEL,CABIN1,UBTF,VAV2,VIPR2,SPHK2,KCNAB1,PHTF2" Drug 2427_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASIC1,KIDINS220,PPFIA4,APAF1,APOC1,ASPH,ADAM23,SCAPER,HIP1R,PLAA,QKI,CRY2,GSDME,SGSM2,DTNA,CNNM1,LRRC23,F3,FHL1,FOXG1,AGAP2,IQCG,GATM,NCKAP1L,DHX35,MAP4,NF1,NINJ2,NUMA1,PDE4D,CNNM2,RGS10,ZNF671,ZNF821,SMTN,FAM214B,SLC6A8,CCDC88A,EMC1,NCDN,ATP11A,ADGRL3,TCF7L2,CHST8,ICAM5,TRPS1,REEP1,WNK1" Drug 6833_DN (-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "AP2A2,ALCAM,ATM,CFLAR,SCAPER,BTRC,CACNB2,FOXN3,TAOK2,ENTPD4,CRY2,GREB1,PARD6A,DTNA,SIDT2,SORBS3,ZNF589,FGFR1,SEMA4D,GPR153,OGA,INPP5K,TXNL4A,GRB10,ATXN2L,HSD17B1,KCNJ3,MAP4,NEK1,SLC11A2,NUMA1,PCDH9,RETREG1,PRKAR1B,RAB3A,RAD51D,RAD52,ANKRD6,SMTN,COA1,CEP68,TTBK2,PHLDB1,TCF12,PSD3,TMEM121,ZMYND8,PLPPR2" Drug 346_UP 2-propylpentanoic acid; Up 200; 2000uM; MCF7; HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "NME5,ANK2,AQP6,NRP2,BMP7,GYG2,RAB29,SYNGR3,CHRM4,ECE2,RASSF2,JAKMIP2,TMCC2,EFNA3,TNK2,EXTL2,ARMCX1,TUBB4A,ZNF589,FGFR1,CAMSAP1,FYN,SYT17,RUNDC3A,RAB40B,GRB10,ADAMTS6,KCNH2,KIF5C,MMP16,NOS1,MBOAT7,SH3GL3,ASAP3,ST6GAL1,SYBU,KBTBD4,ZCCHC24,ELOVL4,AGTPBP1,TRIM2,TMEM121,BEX4,TST,DNAJC12,REEP1,MPPE1,IFT88" Drug 2775_UP Epivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "NDRG2,DOC2A,BIN1,APBA2,APBB2,PPFIA3,MARK4,CFLAR,ST3GAL5,GYG2,CACNA1D,CDC42,SRSF11,ZFYVE9,FADS2,QKI,HOMER3,AKAP5,MAGI2,KBTBD11,MBNL2,PDLIM5,TDRKH,GPER1,GPR37,GRM1,SLC2A6,KIT,NDUFA5,NRGN,OMG,CDK18,SLC25A23,PTHLH,RGS3,ZNF821,SH3GL3,SLN,KDM4B,WDTC1,THBS4,TK2,PARD3,TRIO,ZMYND8,HIRA,SLC30A4,EMSY" Drug 5696_DN Androsterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ASPHD1,ADCY6,BIN1,APOC1,ARRB1,ATM,CFLAR,CDK5R1,MTMR2,CLGN,PLEKHB1,QKI,HOMER3,DCAF8,GIT2,DBT,JAKMIP2,LYPD1,DTNA,PHF20L1,FGFR1,BAIAP2,PRELID3A,GLYR1,RNFT2,HNMT,HSD17B1,MAP4,MDM4,MMP16,ZNF862,NFYA,SLC25A23,PPP2R2B,RXRA,FERMT1,SIRT2,ZHX3,SPTAN1,NCDN,SEMA4A,MCF2L,TCF7L2,MICAL1,XRCC4,ZBTB14,WNK1,SMIM8" Drug 5316_DN Glycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "AP1B1,CDC42BPA,ANK3,PPFIA3,BCL7A,AP4M1,ARMC8,NCOR1,ARHGEF10,SIPA1L1,DZIP3,KIAA0513,SMG7,DPH1,SORBS3,SEMA4D,CSPG5,SRCAP,COPS8,MAP4K5,HSF2,KIF5C,MAP4,MBD1,MEIS2,PTOV1,NACA,PDE3B,SSH1,RAD51D,ARHGEF10L,PEX26,SCMH1,KIF1B,TROVE2,CAMTA2,ELOVL4,FBXW11,TCF7L2,TRIM2,TIAM1,BHLHB9,KCTD2,RBFOX2,HIRA,MPPE1,PDSS2,SMIM8" Drug 2893_UP Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ACTN2,ATM,SLC2A11,CADM3,CACNG1,HIP1R,ARHGAP33,FOXN3,CHRNB2,ZFYVE9,FADS2,LY86,ST18,CDON,EFNB3,TNK2,SEMA4D,GAB1,SEPT9,ATP8A2,SRCAP,RND1,GRIN1,GRM7,GRM8,HTR2A,BCO1,NDUFA5,NF1,NUMA1,PDE1C,PLCD1,SLC25A23,CEP41,PRKAR1B,PRKCB,ZMAT4,RGS12,SATB1,NFASC,VAMP1,PCDHGA10,SYNE1,CRTC1,TK2,R3HDM1,FLRT2,MVB12B" Drug 7089_DN lomustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ADD3,SRPX,ANK3,CASK,CDK13,KIF1A,SYNJ2,MTMR2,MAGI1,RAB26,HOMER3,WHRN,PDE4DIP,DZIP3,E2F5,EIF5,ARMCX1,DLC1,TESK2,SYT17,SRCAP,MALT1,ZNF276,GPR19,GPER1,BRINP3,JAK2,MBNL1,MPP2,ADAM22,PRODH,SYTL2,GON4L,SUSD4,ARHGEF10L,FERMT1,AMBRA1,SMTN,SLC15A2,SMARCA4,SPATA7,CDK19,CEP68,TACC1,ANKRD12,KAT6B,ZBTB14,SEMA3B" Drug 4141_DN Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ADORA2A,KIDINS220,PLA2G6,MRTFA,MARK4,BRINP2,ATM,CFLAR,SCAPER,GYG2,CFAP410,CCNT1,CBFA2T2,ASIC3,FADS2,QKI,ARHGEF10,GREB1,DRD1,ERCC2,FGFR1,GAD1,RAB30,FERMT2,PRRC2B,PCLO,GRB10,NR3C1,DHX35,IL6R,KCND3,KCNF1,KIF5C,GIT1,NDUFA5,NUMA1,MAPK8,ZSCAN32,SLC25A36,LIMS2,SNCA,THSD1,EXOC7,PCDHGB6,R3HDM1,XRCC4,WNK1,SCG2" Drug 6774_DN Anabasine [494-52-0]; Down 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ALCAM,MRTFA,APBB2,CDK10,ASPH,NUMB,ARHGEF7,SCAPER,CBFA2T2,TAOK2,ABCG1,CSNK1E,CTH,DTNA,TOM1,SORBS3,ELAVL3,SCML2,FGFR1,FOXG1,SMC2,FAM49B,INPP5K,MAP4K5,ELOVL5,NF1,NNAT,CCSER2,RETREG1,ZSCAN32,ATG16L1,FAM184A,ZNF821,SOX3,CLSTN2,ELOVL4,ARC,KAZN,TCF7L2,TNS2,TMOD1,BEX4,CDK20,TRPC1,LMF1,XRCC4,SEMA3B,EPM2A" Drug 5355_UP Lynestrenol [52-76-6]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.26E-04 1.00E+00 5.38E-03 6.12E-02 48 194 "ACTN2,APBB2,CFLAR,ST3GAL5,KALRN,SLIT2,MICAL2,SIPA1L1,EGFR,EGR3,ERCC2,SRCAP,GLYR1,GNG3,GNG4,NR3C1,ATXN2L,JAK2,IPO5,MAP4,MDM4,MIA2,SLCO1C1,NPTX1,PDE4B,SMOX,POU3F4,CNNM2,TMEM104,RGS10,KCNIP1,SH3BP2,SYBU,ZNF365,SLC9A5,LIMCH1,TSNAXIP1,POPDC3,TRIM2,SPX,ZNF34,DAAM2,TRPM2,LAT2,XRCC4,NDRG4,SEMA3B,NAV2" Drug CID000472252 racemates Stitch 7.26E-04 1.00E+00 5.38E-03 6.12E-02 9 18 "ABHD6,BOC,RCAN1,RCAN2,EFS,ATP8A2,GRM3,SCN2A,HHIP" Drug CID000122081 LOE 908 Stitch 7.26E-04 1.00E+00 5.38E-03 6.12E-02 9 18 "ASIC1,ADD3,CACNA2D1,EDN1,EDNRA,EDNRB,PTK2B,MAPK3,TRPC1" Drug CID000002809 clorazepate Stitch 7.26E-04 1.00E+00 5.38E-03 6.12E-02 9 18 "SEMA6A,TPP1,EGR3,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug 5413_UP Methiothepin maleate [19728-88-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-04 1.00E+00 5.40E-03 6.14E-02 47 189 "ALK,APAF1,GAS7,APOC1,CDC14B,CFLAR,GYG2,CACNA1I,CAMK2G,DNAJB5,QKI,FHL5,ARHGAP24,DTNA,OPTN,EGR3,ETV1,PTK2B,ATP8A1,FHL1,SRCAP,GLYR1,GLS,NR3C1,RASSF8,ATXN2L,KCNJ4,MSR1,MYO7A,MAPK10,PTPRE,RAB5B,SELL,STUM,ASAP3,SHANK2,PLCB1,MCF2L,TRIM2,RPGRIP1L,ZNF34,ZKSCAN5,DNAJC12,SYNC,SEMA3B,NAV2,SLC17A7" Drug 4401_DN Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.29E-04 1.00E+00 5.40E-03 6.14E-02 47 189 "APP,CDK13,EIF4G3,CFLAR,CDK5R1,GYG2,SOCS6,TAOK2,SLIT2,RAB28,SLC4A7,C2CD2,AKAP12,ZFYVE16,DTNA,EGFR,EML1,F3,FGFR3,SYNCRIP,GAD1,USP19,MALT1,CNTRL,NR3C1,NF1,RETREG1,PLCD1,GRAMD1C,ITSN1,TTC17,LIMCH1,RBM34,SPART,CLASP2,FAM168A,KLHL7,TACC1,EXOC7,TCF7L2,TMPO,BEX4,VGF,ZIC1,REEP1,EPM2A,ST7" Drug 6649_DN Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.29E-04 1.00E+00 5.40E-03 6.14E-02 47 189 "MTUS1,NME5,C1QTNF1,APC,STX16,CFLAR,SYNJ2,CCNT1,HOMER3,VCAN,PDE4DIP,SMG7,EDIL3,EGFR,COQ7,EPHA5,SCML2,EFEMP1,KIAA1109,BAIAP2,SEMA4D,FYN,KIF5C,NEK1,NF1,NUMA1,LRP12,POLG,MED1,WDR25,PTPRN2,PLEKHB2,ATG16L1,AMBRA1,KDM4B,UNC5B,COLGALT2,TCF7L2,PSD3,ATP13A2,TRIO,UBTF,ZBTB14,ZNF24,MAP3K12,SNX27,KAT6A" Drug 3690_DN 0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.29E-04 1.00E+00 5.40E-03 6.14E-02 47 189 "ABR,ACTN1,MTUS1,ALAD,PKP4,HAP1,LARGE1,ZFYVE9,PLAA,KIAA1549L,HOMER3,DZIP3,TOX,DMPK,RRAGB,FGF1,PDLIM5,ZMYND11,GART,GBX2,GLYR1,PSRC1,EML4,ELOVL5,AGFG1,MBNL1,PIK3R1,PLEC,PTN,ATG16L1,TCP11L1,DZIP1,BTBD7,EMC1,PEG10,CDK19,SS18,TCF4,TRIM2,TIMP4,TRIO,LAT2,NSD2,XRCC4,NAV3,MPPE1,UBE3B" Drug 1019_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.30E-04 1.00E+00 5.40E-03 6.14E-02 44 174 "LTBP4,OGT,APBB2,BACH1,SYNJ2,REPS2,PDE4DIP,NOS1AP,INTS1,DBT,DNM1,ING4,EZH1,TESK2,ZNF589,HBS1L,ERAP1,INPP5K,BRD8,GLS,STON1,GRIK5,HNMT,LMO2,MXI1,LYRM9,ZNF862,MINDY2,CNNM2,PTCH1,RALGDS,BSDC1,PAQR6,ASAP3,SLC9A5,BTBD7,KDM3A,CDK19,CEP68,SZT2,NR2C2,RUNDC3B,MARCH8,UBE3B" Drug 6177_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.30E-04 1.00E+00 5.40E-03 6.14E-02 44 174 "CLK4,GRAMD1B,BTRC,CAMK2G,KRIT1,CD38,TPP1,CREM,PDE4DIP,DGKG,HS3ST2,EFNA3,FAM13A,MBNL2,MRNIP,VPS13B,KIAA1109,FGFR1,BAIAP2,C1orf61,CAP2,AGAP2,ATP2C1,STON1,MUM1,CD200,NRCAM,NTRK2,KCNK10,PDE4B,PDE4D,MBOAT7,PPM1B,PRKACB,MAPK7,HSPA4L,KDM4B,SPATA7,ARHGAP26,SPTAN1,TPM1,FLRT2,ZBTB38,FXR1" Drug CID000104727 aluminum Stitch 7.30E-04 1.00E+00 5.40E-03 6.15E-02 46 184 "SERPINA3,ADCY2,ADCY5,ADCY6,ADCY8,ALAD,APBB1,APBB2,APP,ATP1A1,BCHE,DST,CALM1,NGB,CNOT8,TBPL1,PLCXD3,ARHGAP32,BSCL2,ELN,GNAL,GNAS,GNG3,GPT2,STON1,HBA1,IDH3A,IDH3B,MAP2,MAPT,NEFM,NEFH,NOS1,ANLN,PKM,PLCB2,PLCD1,PPP3CA,PPP3CC,RELN,QDPR,SNCA,PLCB1,TBL1X,TF,CABIN1" Drug 5210_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.30E-04 1.00E+00 5.40E-03 6.15E-02 46 184 "ADRA1D,OSBPL1A,BIN1,APBA2,GAS7,ST3GAL5,CLU,DNAJB5,CTH,EDRF1,INTS1,RUSC2,CDON,ATN1,RCAN1,MBNL2,BAIAP2,FOXG1,AFF2,SORBS1,ATP2C1,ERAP1,SRCAP,GLYR1,GRB10,DIDO1,NR3C1,NAP1L2,NF1,OXTR,PLCD1,DCHS2,KLK6,RAD52,HSPA4L,SGK1,SH3BGR,CPEB3,CCDC88A,KIF1B,TRIM2,ZMYND8,UCHL1,VLDLR,PRDM2,FXR1" Drug 2946_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.30E-04 1.00E+00 5.40E-03 6.15E-02 46 184 "BIN1,APBB2,ST3GAL5,CD86,AP4M1,ZFYVE9,TPP1,CREM,ABCG1,SIPA1L1,VCAN,PPP1R16B,SPOCK2,TRAPPC9,FAM13A,PRELID3A,COPS8,PRUNE2,PADI2,HNMT,TJAP1,VWA5A,LSS,MEF2C,MIA2,NRCAM,PDE3B,PDE4B,CCSER2,RETREG1,PILRA,PRKCZ,MAPK7,RAB3IL1,RXRA,SHANK2,TNIK,SPTAN1,THSD1,EPB41L3,SYT5,PDLIM2,SLC44A1,TNS1,TPM1,UBTF" Drug 3630_UP 0179445-0000 [211246-22-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.31E-04 1.00E+00 5.40E-03 6.15E-02 45 179 "MRTFA,APOC1,ARHGDIG,FUBP1,SCAPER,CACNA2D1,CAMK2B,CCNT1,AKAP6,CRMP1,VCAN,EDRF1,CTIF,FEM1B,REEP2,FAM198B,IP6K2,CELF1,HBS1L,SRCAP,SESN1,GLS,HRH3,ATXN2L,CD200,NELL2,NFYA,CNOT4,NPY,SMIM7,PPP2R5C,VPS13C,FAM120C,FBXW7,RPS20,SFPQ,DZIP1,PPP4R3A,ZSWIM8,ZBTB43,DDN,DICER1,ZMAT3,VIPR2,MKRN3" Drug 2694_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 7.31E-04 1.00E+00 5.40E-03 6.15E-02 45 179 "APBB2,MARK4,HIP1R,INA,DNAJB5,RAB26,PDE4DIP,RUBCN,KIAA0513,RIMS3,DNAJC6,MAMLD1,EFNA3,MBNL2,TBC1D16,TESK2,FER,RND1,GOLGB1,KIF3A,RNFT2,KIF5C,MEF2C,SCAMP5,NCAM1,PCDH9,SERPINI1,CCSER2,SEPT4,TTLL7,RPS20,ASRGL1,PALLD,ZSWIM8,SPTAN1,ELOVL4,RGL1,STXBP1,SYT11,MTCL1,CAMSAP2,TRIM2,RPGRIP1L,HEY1,SLC17A7" Drug CID000130594 NBD-colcemid Stitch 7.41E-04 1.00E+00 5.48E-03 6.23E-02 11 25 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,NPPA,ADHFE1,TUBB2A,TUBB1,TUBA1A" Drug CID005322157 AC1NT1AF Stitch 7.41E-04 1.00E+00 5.48E-03 6.23E-02 11 25 "ASIC1,ASIC3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TAC1,TAC3,TRH" Drug CID006439511 HF-2035 Stitch 7.41E-04 1.00E+00 5.48E-03 6.23E-02 11 25 "CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,DAPK3,CAMKK2,MYLK2,NOS1,CAMKV,CAMK1G" Drug CID000001310 "1-aminocyclopentane-1,3-dicarboxylate" Stitch 7.46E-04 1.00E+00 5.52E-03 6.27E-02 31 111 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,C5,CHRM1,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,LMO2,MAP4,OMG,PRKCB,PRKCG,MAPK3,PLD4" Drug CID011947681 nitroprusside Stitch 7.46E-04 1.00E+00 5.52E-03 6.27E-02 31 111 "RALGAPA1,ADCY6,AGT,ALDH7A1,CACNA2D1,CBS,CNTN1,CTH,DMPK,NR1D2,EDN1,EDN3,F3,F5,BRD8,GUCY1A2,GUCY1B1,BCO1,NOS1,NPPA,NPR2,NPTX1,NPTX2,PDE2A,PDE3A,PDE3B,MAPK3,ACER3,SLC12A2,PEG10,TLR4" Drug CID011979316 vasopressin Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 85 388 "ADCY2,ADCY5,ADCY6,ADCY8,SLC12A5,ADRA1D,ADRA1B,ADRB2,AGT,ALAD,AQP4,AQP6,PDE8B,STX16,CCK,CD38,LRBA,CLCN3,CLCN4,AKAP7,PLCXD3,EDN1,EDN3,EDNRA,F8,TPK1,GALR1,INPP5K,GNAS,PLCD4,HPS5,CPT1C,HTR2A,AQP11,NNAT,NPY,NPPA,NPR2,NPTX2,NUCB2,OXTR,PCSK2,PDYN,PENK,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,KLK6,PYGM,CLIP1,SAFB,MAPK12,SCNN1D,SGK1,SCG5,SLC12A2,SLC14A1,SST,PLCB1,TAC1,TAC3,AZIN2,PIK3R5,TRH,UBC,VGF,CLIP2,WNK1,HPS4,WNK3,PLD4,SLC17A6" Drug CID000142559 diphosphene Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "CBS,DMPK,ITIH2,PMP2" Drug DB00201 Caffeine Drug Bank 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ADORA1,ADORA2A,PDE4B,RYR1" Drug CID005329388 aminothiazole 6 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIK1,GRIK3,GRIK4,GRIK5" Drug CID003018579 diCl-HQC Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIK1,GRIK3,GRIK4,GRIK5" Drug ctd:C044610 etizolam CTD 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GABRA2,GABRA3,GABRA5,GABRG2" Drug CID006914513 AC1OCA3P Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "BOC,B3GAT1,TAC1,TACR1" Drug ctd:C102280 LY 306740 CTD 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "PDYN,PENK,TAC1,TACR1" Drug DB01303 Oxtriphylline Drug Bank 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ADORA1,ADORA2A,PDE3A,PDE4A" Drug CID000022741 4-phenoxybutyric acid Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ABHD6,EDN1,EDNRA,EDNRB" Drug CID000120220 Brn 1074551 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIK1,GRIK3,GRIK4,GRIK5" Drug DB00996 Gabapentin Drug Bank 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ADORA1,CACNA1B,CACNA2D1,CACNA2D2" Drug CID004223812 sunifiram Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011105661 4-(chloromethyl)-3-methoxy-5-methylisoxazole Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000158974 acromelic acid B Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIK1,GRIK3,GRIK4,GRIK5" Drug CID000022860 AC 110 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "CACNA1A,CACNA1B,CACNA1E,CACNA2D1" Drug CID000128573 DMIPP Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "KDM5D,AMH,INPP1,SMUG1" Drug CID009571043 R 80122 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ALDH7A1,CACNA2D1,PDE3A,PDE3B" Drug ctd:C096324 botulinum toxin type C CTD 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "SLC12A5,STX1B,SNAP25,STX1A" Drug ctd:D000122 Acetylthiocholine CTD 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ACHE,BCHE,CHRNA4,CHRNB2" Drug CID000359501 NSC290205 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "ARSE,GNAS,MX1,TMEM132D" Drug DB01205 Flumazenil Drug Bank 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GABRA1,GABRA2,GABRA3,GABRA5" Drug ctd:D001030 Apamin CTD 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "KCNN1,KCNN2,KCNN3,TAC1" Drug CID000174812 CP 205 Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "MAPK3,MAPK8,SYT1,SIRT1" Drug CID000066605 "2,4,6-triaminotoluene" Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "DYNLL1,ANLN,RDX,TNNT1" Drug CID009964065 3-isoxazolol Stitch 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "GRIA1,GRIA2,GRIA4,GRM3" Drug DB07574 "2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE" Drug Bank 7.50E-04 1.00E+00 5.52E-03 6.28E-02 4 4 "TUBA1B,TUBA1C,TUBB2B,TUBA1A" Drug ctd:D012969 Sodium Fluoride CTD 7.56E-04 1.00E+00 5.56E-03 6.33E-02 187 958 "ACHE,ACTN1,ELFN2,ZNF608,SNX32,TBC1D14,ALAD,OGT,APBB1,APOC1,SHTN1,ARHGAP5,ATM,ATP1B3,BCHE,KSR1,SCAPER,CACNA2D1,CANX,CDC25B,CDC27,CDH2,IGFN1,CHN1,SYNPR,CHRNA4,RAB3C,RAB28,CLU,CLTC,RAB26,MFSD4A,CP,AKAP12,CS,CSNK1G3,ATRNL1,CST3,GPSM1,DAPK1,DAPK3,SIRPA,DBN1,DLG2,RAB39B,TRAPPC9,CASP8AP2,ATN1,EEF1A2,HIPK3,GPR61,ASB3,TNK2,EPB41L2,SLC43A2,APC2,TUBA1B,PRAM1,TUBB4A,FGR,STAMBP,ZMYND11,NCKAP1,TUBA8,ARFIP1,GFRA1,PCDH17,NTNG2,RAB30,GOLGB1,LILRB4,DIPK1C,GPR12,TUBA1C,GRM5,RNF165,RASSF8,BACH2,HNRNPK,HSP90AA1,IDH3A,IGF1,LRRC25,DOCK7,IL6R,TUBB2B,KCNA1,KCNH1,STMN1,HECTD2,ASPRV1,MBD1,MBP,MEIS2,SRSF12,MMP16,CTNNA3,NAP1L1,NEFM,CCDC13,NFE2L2,NFYA,NINJ2,NPR2,ODF2,OPRL1,CLDN11,GLIPR1L2,PAK3,PCSK2,PDE4D,OLA1,NALCN,XRN1,PKM,PLP1,FAT3,PPP1R1A,PPP2R2B,PPP2R5C,PPP3CA,PRKACB,PRKCB,MAPK3,PRPSAP2,SIDT1,PTPRG,ZSCAN2,RAB3A,SLC25A48,FAM184A,RBBP6,RBBP8,RDX,CRTAC1,REV3L,RNASEL,KCNIP1,ATXN1,SCN4B,FNIP1,ITSN1,MYO18A,SLC6A9,KDM4D,NAPB,CPEB4,SORCS3,SMARCE1,RCOR3,SCN3B,BDP1,SPP1,ST5,CEP68,GANAB,FGD4,ABCC8,SYP,CLASP1,AZIN2,PCDHB15,TEX15,SIRT1,ITGB3BP,AP4E1,MTMR14,TIE1,HEY1,TJP1,ICAM5,TMPO,DCBLD1,TUBB2A,TUBB1,DNAJC12,MTCH1,TBC1D15,SLC13A3,ZFP37,CELF4,ANKS1B,TUBA1A,SNX14,NETO2,CPNE4,JPH3" Drug CID000025701 cysteic acid Stitch 7.72E-04 1.00E+00 5.68E-03 6.46E-02 22 70 "CBS,SULT4A1,PHC2,FOLH1,GAD1,GAD2,SULT1C4,PCSK1N,GRIK1,GRIK4,GRIK5,LSS,CHST6,OGDH,OMG,GAL3ST4,SLC1A2,SLC1A3,CLSTN2,CHST8,CHST5,GAL3ST3" Drug CID000001136 M-HT Stitch 7.72E-04 1.00E+00 5.68E-03 6.46E-02 22 70 "SERPINA3,ACHE,APLP1,APOC1,BCHE,RUNX1T1,CBFA2T2,CHN1,CLU,CNR1,CX3CR1,CD320,GART,GLUL,HNMT,MAPT,MAPK8,MAPK9,SYP,TTPA,ZIC1,NETO1" Drug CID000010457 suberate Stitch 7.76E-04 1.00E+00 5.71E-03 6.49E-02 19 57 "ACADM,APOC2,BCHE,NSL1,CALCRL,EPB41,GAP43,GRIA1,GRIA2,GRIA4,NCF2,NPY,PTN,SCN2A,SLC1A2,SLC1A3,TGFBR3,THRA,VIPR2" Drug CID000006395 methanesulfonate Stitch 7.76E-04 1.00E+00 5.71E-03 6.49E-02 19 57 "CBS,F3,GRM1,GRM5,KCNJ5,NBL1,OPRL1,P2RX7,PDCD2,PDYN,RYR1,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC12A2,SPX,TP53BP1,KCNT2" Drug CID000036811 dobutamine Stitch 7.76E-04 1.00E+00 5.71E-03 6.50E-02 37 140 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,NR0B1,ALAD,AQP4,ALDH7A1,AP1M1,CACNA2D1,VCAN,DBT,DMD,ERBB2,FOXO3,MSTN,GK,BVES,HP,HPR,IGF1,ITGA7,KCNJ5,MYH6,PDE3A,PDE3B,PDPK1,PKN2,TET1,SMUG1,TSC1,TSC2,RICTOR,ZIC3" Drug 2725_DN Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ASIC1,SLC12A5,ADRA1D,AMPD3,APC,PPP4R4,ASPH,ATP2A2,CACNA1A,EPS15L1,HOMER3,IQCK,NRG2,PPP1R16B,USP6NL,SV2A,RABGAP1L,RCAN1,EFNB3,IGSF6,KIAA1109,IQCG,SEPT9,GPR75,POLL,ATXN2L,IFI16,KPNA5,SMAD1,NNAT,TMEM104,PTAFR,FAM120C,RGS10,ZNF821,ANKRD6,SLC11A1,TMCC1,TROVE2,NCDN,FAM168A,EXOC7,ADGRL3,KIAA1107,PSD3,TK2,LMF1,MAP3K12,TIGD6" Drug CID000005775 phentolamine Stitch 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,APOC2,ATP1A2,ATP1A3,ALDH7A1,CACNA2D1,CCK,CHRM1,CHRNA4,CHRNB2,CRYBB1,DLG3,DMPK,DRD1,EDN1,ARFGAP2,B3GAT1,GABRA1,GCNT2,HRH3,ATXN2L,HMX1,HTR2A,HTR5A,BCO1,NF1,NOS1,NPY,OPRL1,PDYN,PENK,PYGM,RET,SST,TAC1,TAC3,TACR1,TRH,UBTF" Drug 6321_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "NME5,SHROOM2,KIF1A,ST3GAL5,SCAPER,LDLRAD4,CBFA2T2,CPS1,CRMP1,SUSD5,PDE4DIP,CNTNAP2,TBC1D5,RIMS3,MFAP3L,KIAA0753,MRNIP,PLEKHO1,STX2,SCARA3,DENND2A,GPR22,PTGDR2,HNMT,KCNK1,KCNN1,MAPT,AFF1,NTRK3,ODF2,LRRN3,MAPK8,SCN8A,FNDC3A,CCDC88A,SNCA,KDM4B,ZHX3,PHLDB1,SYN2,PCDHGA10,TIAM1,R3HDM1,CABIN1,TRIO,WIPF1,NT5M,UBE3B,PHTF2" Drug 4178_UP Furazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "DPF1,AGT,AMPH,APBB2,SEMA4G,RGS20,ASPH,BRINP2,ATP1A2,N4BP2L1,CLCN4,HOMER3,NCOR2,ARHGAP24,RIMS3,DAPK1,DCT,DRD1,C3orf18,PIPOX,F5,ZNF589,FGF12,AGAP2,IQCG,FAM49B,PNMA2,ZNF44,ADAMTS8,GRM7,GUCY1A2,IL6R,KCNMA1,MID1,MN1,KCNK10,PCDH8,GPR85,PFKFB2,RFX3,SCN2B,PPP1R9A,BEX1,MAPK8IP3,PHLDB1,PCDHGB6,HIF3A,TIMP4,ZNF711" Drug 3477_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ABHD6,ALCAM,CDC42BPA,APC,EPB41L5,FAM131A,ADAM15,ST3GAL5,QKI,BAG4,CTH,C2CD2L,TRAPPC9,CELSR3,PHF20L1,TNK2,F3,GPR153,DISC1,GCNT2,TXNL4A,RAB30,CNTRL,NR3C1,LSS,MAP4,ODF2,PTPN13,RALGDS,MSANTD2,NEK11,SMARCC2,MAPKBP1,RBM34,GLT8D1,EMC1,SPART,THSD1,FCHO1,ELOVL4,SEMA4A,TBL1X,BEX4,PARD3,TRPC1,UBTF,LMF1,REEP1,MAP3K12" Drug 4807_DN Nystatine [1400-61-9]; Down 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ABHD6,AP2A2,ATM,CFLAR,SLC25A14,SOCS6,NMT2,QKI,AKAP7,DBT,FBXL5,SACS,SUGP2,EPB41L2,STX2,F3,CAMSAP1,TRMO,STAU2,ITPKB,JAK2,MEIS2,NF1,NOS1,CCSER2,STRN3,WDR25,PPM1E,ABLIM3,LIMCH1,KIF13A,ERC1,SPART,ZNF302,NEK4,KANK1,SYT1,FAM208A,DMXL2,SATB2,TCF7L2,DOCK9,TMPO,RBFOX2,KCNK12,REEP1,UPF3A,ACTR3B,GAN" Drug 4971_DN Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ACTN2,ADRA1D,AK2,EP400,APP,KIF1A,CACNA1D,CDC27,RCBTB2,CLU,FAM189A2,JAKMIP2,DNM1,TSPAN5,EDNRA,EFNA3,SORBS3,IRAK4,BAIAP2,OGA,SRCAP,RAB30,GNG3,GNG4,GRIK5,CACFD1,IPO5,LMO2,ZNF862,NPTX1,SETD4,PDE3B,MBOAT7,MAPK7,PTHLH,ZCWPW1,TTC17,RBM34,FNBP1,UNC5B,MAPK8IP3,STX1A,SEMA4A,ROBO3,TCF7,RPGRIP1L,KCTD2,VIPR2,EVI5" Drug 4966_UP Lysergol [602-85-7]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "NDRG2,MRTFA,TRMT9B,APBA2,APLP1,FAM131A,PRX,LDLRAD4,BRSK2,CBFA2T2,ADGRG1,ARHGEF6,CSF1,TENM4,PDE4DIP,MFAP3L,DMPK,SIDT2,DMTN,ERCC2,RASL12,ZNF589,SEMA4D,SRCAP,POLL,KLF12,IRF8,INPP5B,ITGA7,KCNJ5,AFF1,NNAT,RETREG1,NLE1,PPP5C,ATG16L1,ZNF493,RGS10,EMID1,FOXRED2,SLC1A7,SLN,DOP1A,ZBTB43,POPDC3,EXOC7,ZEB1,PCDHGB6,PIK3R5" Drug 6293_DN Melatonin [73-31-4]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "MTUS1,ATM,CDK5R1,C5,HIP1R,SPAG9,NMT2,ABI3BP,HAPLN1,GIT2,DBN1,SMG7,SPOCK3,RCAN1,TNK2,EN2,FCGRT,POLR1B,EFCAB2,ERAP1,TXNL4A,MSL3,GNG4,MAN1B1,DHX35,MITF,PC,PDE1C,PIK3R1,LRP12,MINDY2,MAPK3,SH3TC2,GAL3ST4,SLC25A36,TCP11L1,SBF1,KDM4D,IFT122,TMCC1,ZBTB43,SYT11,JMJD6,EXOC7,CABIN1,ZNF142,TFIP11,MAP3K12,PLSCR4" Drug 6520_DN Dimaprit dihydrochloride [23256-33-9]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ALCAM,MRTFA,BIN1,CDC14B,SEMA4G,PDE8B,MTMR9,CACNG1,CRLF1,CHRNB2,FAM189A2,NRG2,ARHGAP24,DAPK3,GIT2,PARD6A,EXOG,TRAPPC9,SUGP2,MRNIP,MTSS1L,CDKL3,VPS26C,INPP5K,GNG4,GRIK5,GRM1,ELOVL5,KCNH2,KCNMA1,GIT1,NNAT,NRGN,SETD4,PLXNB1,PPP5C,PTN,RAD51D,ZDHHC14,RGS10,SMTN,SLC20A2,SS18,AJAP1,VAMP1,CHST8,GPR161,TMOD1,BEX4" Drug 4975_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "NDRG2,ADD2,ADORA1,AP2A2,ALK,AMPD3,CDC42BPA,ASPH,DDX3Y,ALDH7A1,CDK5R1,GYG2,SGCE,LDLRAD4,CA4,ARHGAP33,CLGN,CNTFR,CHD5,VCAN,SDC3,NOS1AP,RIPOR2,RASSF2,DBN1,HS3ST2,EDNRB,FUT9,USP19,GLS,GRIK2,NR3C1,KCNN1,KPNA5,NCF2,PENK,GRAMD1C,PTHLH,SCN8A,SLC1A7,SLC2A5,SLC9A5,TNIK,DDN,ARC,POPDC3,WSCD1,TEX15,TRPM2" Drug 5969_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ARID1A,ADCY2,MTUS1,PTCH2,RASL11B,BMP7,CACNB2,RAB28,HOMER3,CRMP1,CNTNAP2,EDIL3,FAM13A,CDKL3,CEND1,F5,KIAA1109,SEMA4D,ZMYND11,SIGLEC8,POLL,GNG4,TDRKH,GPR17,DIPK1A,KPNA5,MOBP,GIT1,PALM,PCDH9,MAPK7,PTN,PEX5,RAD51D,BEND5,EMID1,SCN3A,FRMPD1,SLC12A4,ZNF334,SLN,THSD1,SS18,SYT5,ZFPM2,RIMBP2,TPM2,CA14,TFIP11" Drug 2939_DN Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ABHD6,MTUS1,PLA2G6,MRTFA,PKP4,MARK4,C5,BTRC,CAPN3,ARHGEF1,ENTPD6,CDC42,IQCK,CRY2,SLITRK5,MAML1,ECM2,E2F5,SIDT2,PCOLCE2,EIF1,LRRC23,RASGRP2,ECSIT,SEMA4D,ITGAM,LIG4,MATK,MEF2C,NRCAM,ODF2,OGG1,PTPA,SNRK,PTAFR,RET,MRPS18A,ZNF821,WDTC1,STX1A,VPS13A,RPGRIP1L,SYNE1,PSD3,TRPM2,PLPPR2,WNK1,PRDM10,PHTF2" Drug 2677_DN chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "MRTFA,ATP2B1,MPDZ,CAST,MAP7,PLAA,HOMER3,SH2B1,C2CD2L,SMG7,TOM1,DNAJB6,E2F5,FRY,PLXNC1,ELN,PTK2B,SEPT9,MSL3,GNAS,GPD2,LSS,MAPT,MIA2,NFYA,NUMA1,MINDY2,MAPK3,DEF8,TMEM231,GSTCD,ZNF671,SLC6A8,SIRT2,KBTBD4,MAPKBP1,SS18,FAM168A,ARHGEF9,CAMSAP2,TBL1X,TCF7L2,TNS2,R3HDM1,PIK3R5,CDK20,TPM2,CLIP2,WIPF2" Drug 282_DN fludrocortisone acetate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ALAD,EP400,ARNTL,MTMR9,RGS11,MYRF,TBRG4,CHN1,LHX2,SH2B1,CSF1R,PTK2B,FGFR1,SEMA4D,CGREF1,GNAO1,GPM6B,BTN2A1,SOX21,HMX1,ICA1,IGF1,KCND3,KCNJ5,KCNJ10,LAMA2,MAP4,MMP17,ADAM22,CTNNA3,MYL3,SETD4,OCRL,RETREG1,PLXNB1,RC3H2,RNH1,PCMTD2,PREX2,SMARCC2,KDM4B,IQCE,TBL1X,BHLHB9,PDIA2,WNT7A,ZNF142,MVB12B,AAAS" Drug 4701_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ADRA1D,BIN1,APBA2,APBB2,MARK4,NCOA1,KYAT1,FOXN3,B4GALT6,CLU,AKAP7,BAG4,SH2B1,CSF1R,SDC3,ARHGEF4,MFAP3L,SMG7,RABGAP1L,DTNA,ST3GAL6,FHL1,CGREF1,FYN,TRAF3IP2,ERAP1,INPP5K,GFER,MSL3,GNG4,TDRKH,HNMT,KPNA5,NDUFA5,NEUROD1,PDE3B,PDPK1,PRKAB2,CNNM2,ZCCHC24,ARHGAP26,RPGRIP1L,PSD3,PARD3,TPM1,VIPR2,XRCC4,KAT6A,TIGD6" Drug 2534_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ABHD6,SRPX,APBB2,PPP4R4,ASPH,ALDH4A1,SMARCAL1,RIMS2,ZNF337,GSDME,DYRK1A,ST8SIA3,SEZ6L2,CELSR3,COQ7,FHL1,CAP2,AGAP2,PDLIM5,GABRA4,GAD2,GATM,GLS,PCLO,KLF12,HTR2A,KCNB1,KIT,NEUROD1,ZFYVE21,PPP5C,PTH1R,PID1,MAP6D1,SEMA6D,LIMS2,CCDC88A,SLC11A1,SOX10,TACR1,DNMBP,IQCE,TCF7L2,PSD3,TMOD1,TRPS1,ZMYND8,CLIP2,STMN4" Drug 1685_UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "AP2A2,KCNAB2,APC,CDC14B,ARHGDIG,ATM,BMP7,HIP1R,KYAT1,CCNT1,FOXN3,B4GALT6,RAB28,BAG4,GPRASP1,RIMS3,FCF1,MBNL2,LRRC23,ERCC2,NCALD,BAIAP2,GAP43,GNG4,NR3C1,INPP5B,MAP4,NFYA,PCDH9,CDK14,FSD1,RAD51D,ROM1,SEC14L1,TRA2B,ITSN1,FBXO11,FNDC3A,BTBD7,ZCCHC24,HECW1,KDM4C,CEP68,EXOC7,TCF7L2,TRIM2,TRPC1,PRDM2,GDPD5" Drug 2314_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "OGT,ASCL1,RASL11B,CADM3,GYG2,CH25H,CCKBR,USP2,SEPT7,CDC42,FADS2,CNTFR,AKAP7,CREM,ATRNL1,CHD5,NOS1AP,RUSC2,EDNRA,EFNB3,ATP8A1,AGAP2,DCTN2,GAB1,GRM1,GRM2,ITGAM,KCNC1,KCNJ5,MAN2A2,ADAM22,BCO1,MYO7A,NOVA2,NPR2,PPP2R2B,PTHLH,ZFHX4,MYH14,WLS,CLIP1,SLC30A10,BCAN,SLC9A5,TACC1,PARD3,LAT2,SLC30A3,DNALI1" Drug 4413_DN Vitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ARID1A,MRTFA,OGT,APP,CDC14B,CDK5R1,CBFA2T2,NEURL1,PLAA,DNAJB5,QKI,CNTN1,SLC4A7,NECTIN3,RIMS3,DBT,ERCC2,DENND4A,FGFR1,BAIAP2,IQCG,TRAF3IP2,HBS1L,NCKAP1,USP19,KCNMB4,NR3C1,ATXN2L,TJAP1,IL6R,KCNN1,MMP16,MPP2,NF1,NRGN,PLCD1,SLC25A23,LRP12,MAPK7,NKAIN1,ZFP30,SNCA,EXOC7,WSCD1,DMXL2,SZT2,KCNK12,ZNF45,SSPN" Drug 2988_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "C3orf14,PLA2G6,ANK3,ATP2B2,CLGN,AKAP7,FAM149A,BRINP1,SGSM2,C3orf18,EPB41,RASGRP2,PIPOX,DLC1,EFCAB2,GAB1,INPP5K,WASF3,GATM,ALDH1L1,AHDC1,ADAM28,LILRA2,GRK4,GRM7,KCND3,MAPT,MOBP,MAPK7,ZSCAN32,ZCWPW1,ZDHHC14,RGS3,MAP6D1,RASA3,NLGN1,KIF1B,SPART,CEP68,SYT5,TNNT1,TNS1,TPM1,TRO,LMF1,SEMA3B,PCBP4,FAM13C,JPH3" Drug 6264_UP Tropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "AMPD3,ASPH,KSR1,CAMK2B,PLEKHB1,VAX2,QKI,DAPK3,EFNA3,ELAVL3,OLFM1,SORBS1,PDLIM5,GABRA2,USP19,GPR19,ATXN2L,TJAP1,KCNF1,KCNN1,NF1,NUMA1,PENK,PLTP,PRKCB,MAPK7,GON4L,WDR25,ATG16L1,RGS3,RGS10,RGS12,FBXW7,RPS6KA2,KCNIP1,ZFP2,ZFP30,BTBD7,WDTC1,ZHX3,MAPK8IP3,PLCB1,SEMA4A,PCDHGA10,TRPC1,PLPPR2,KCNK12,WNK1,SEMA3B" Drug 2197_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "RALGAPA1,ABHD6,AMPD3,APBB2,APC,APOC1,KIF1A,CAMK2G,INA,LARGE1,CLCN4,CSF1,SV2A,DTNA,TOM1,EFNA3,PIPOX,PTK2B,GAB1,CRCP,POLL,GNG4,MAP4,NOS1,OCRL,PLP1,PILRA,MAPK3,MAPK8,CNTLN,RIPOR1,RAB3IL1,FAM184A,PLPPR3,SEC14L1,ZNF821,SLC6A8,SLC11A1,MAPKBP1,KDM4B,TSPYL2,DDN,ADGRL3,TCF7,PCDHGA10,PARD3,PLPPR2,VSNL1,ZNF225" Drug 4725_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "SLC12A5,BIN1,APBA2,MARK4,SLC2A11,LDLRAD4,CBFA2T2,AKAP7,CSF1R,ARHGEF10,CSNK1E,BRINP1,SPOCK3,DMPK,CDON,DSCAM,AASS,MRNIP,HSD17B14,FYB1,GAD1,SEPT9,SRCAP,GLS,GNG4,CACFD1,KIF5C,MGAT3,ADAM22,NEUROD1,NPTX1,SLC11A2,NUMA1,RAB3A,RAB3IL1,RGS10,PEX26,WDTC1,MAPK8IP3,STX1A,PLCB1,TRIM2,THRA,TRIO,VIPR2,MICAL1,SPHK2,DNALI1,KAT6A" Drug 3552_DN Milrinone [78415-72-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "AK2,APC,CDK10,PLA2G4C,CACNB2,SULT4A1,CHD1L,CREM,APPL1,CTNND2,GIT2,DBN1,MFAP3L,MED24,EDNRA,ENO2,CAMSAP1,ANKFY1,DPYSL4,GART,GLS,NUDT21,RNFT2,ICA1,ITPKB,MITF,NEK1,NUMA1,RETREG1,MINDY2,PRKAR1B,RAB3IL1,ATG16L1,BTBD7,TMCC1,EMC1,CLASP2,TROVE2,MAPK8IP3,ARHGEF9,IQCE,TCF7L2,AHCYL2,TIAM1,RUNDC3B,LMF1,CLDND1,HPS4,MARCH8" Drug 3097_DN Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "NDRG2,BRAP,MTUS1,PPFIA4,CDK10,ZBTB10,ADAM15,LDLRAD4,HIP1R,NMT2,IQCK,CREM,ZNF337,DNM2,DPH1,DTNA,HIPK3,ENO2,VPS13B,COQ7,PTK2B,FLT1,CAMKK2,GABRA4,SRCAP,GRM1,IL6ST,AFDN,N6AMT1,NUCB1,MAPK7,BEND5,MYH14,TMEM206,TCP11L1,HSPA4L,SLC2A5,KDM4B,DOP1A,WDTC1,TNIK,FCHO1,JMJD6,THBS4,TRPS1,XRCC4,ZNF24,PRDM10,NLRP3" Drug 2759_DN Cytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "AK2,C1QTNF3,CDC42BPA,APBB2,NCOA1,BMP7,CA12,CNOT8,EPS15L1,DNAJB5,CREM,GREB1,CTNND2,SPATA2,PARD6A,DTNA,HIPK3,SORBS3,EPB41L1,ZNF589,POLR1B,FGFR1,DISC1,RAB30,MSL3,CACFD1,BTN2A1,INPP5B,KCNJ3,MITF,SLC25A23,RETREG2,GTDC1,SEC61A2,RNASEL,GSTCD,CLIP1,ELMO2,SLC22A4,COA1,SPTAN1,PCDHA6,TRIO,UBTF,VAV2,CLDND1,WNK1,ST7,UBE3B" Drug 4769_UP Sulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "CDC42BPA,APC,ADGRB3,SYNJ2,BTRC,CFAP410,CDH10,RCBTB2,RAB28,VCAN,DCAF4,HDAC9,GIT2,DCT,FCF1,EFNA3,AASS,F5,FAM198B,DLC1,ZNF589,OLFM1,FHL1,TRAF3IP2,GNAL,GRK4,HAS2,KCND3,KCNH2,KCNMA1,NCAM1,NEFM,NOVA1,PDE4B,LRRN3,ELOVL2,RASGRF1,RFX2,NLGN1,OGDHL,KDM4C,ARHGEF12,TGFBR3,TNS1,LILRA4,TRH,LAT2,WNK1,EPM2A" Drug 1757_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "RBM10,NDRG2,CDK10,PDXK,ARRB2,KYAT1,NEURL1,LRRFIP1,CLGN,JAM2,CLTB,NCOR1,CRYM,FEZ2,PPP6R2,DOCK4,HP1BP3,DNM2,EFNB3,IGSF6,TRMO,USP21,GRB10,CACFD1,IPO5,SETD4,OGDH,OGG1,PACSIN1,POLR2F,RASGRF1,ATXN7,ELMO2,INTS9,CDK19,THSD1,MLC1,TAC3,MCF2L,TMEM151B,TRPM2,TMPRSS5,ZKSCAN5,HIRA,GORASP1,FLRT2,NPDC1,HPS4,URM1" Drug 4320_UP Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-04 1.00E+00 5.95E-03 6.77E-02 49 200 "ADRA1D,PLA2G6,CDK10,PTCH2,NRP2,BMPR1B,FUBP1,BTRC,RUNX1T1,INA,SLC24A2,TPP1,RCHY1,MAML1,CTIF,MFAP3L,DTNB,SYT17,ATP8A2,IL1RAPL1,ICA1,KCNB1,MARK1,MIA2,NFYA,OPRL1,PALM,PIK3CD,PLCB2,TNPO2,POU3F4,PRKCB,PTAFR,ASIC4,ASAP3,NTNG1,SLC1A2,SLC4A3,ZNF334,ZSWIM8,HECW1,IQSEC2,ARC,ATP11A,SZT2,AMACR,ZMYND8,NDRG4,ZNF154" Drug 1649_DN trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADCY6,MRTFA,MPDZ,LHX2,TMEM184B,SMARCAL1,C2CD2,CRY2,MICAL2,CSNK1E,APPL1,DCAF8,RIMS3,DBN1,RBM12,SUGP2,COQ7,POLR1B,FGFR3,GHR,GPR37,BRINP3,ITPKB,KCNJ3,MAP4,NEK1,NRGN,OGDH,POLG,PTPRG,RIPOR1,SUSD4,ITSN1,EPN2,WDTC1,ELOVL4,JMJD6,TACC1,KIAA0930,TCF7L2,CLASP1,UBTF,LMF1,NSD2,SH3GLB2,WNK1,NUP214,ACTR3B" Drug 4792_UP Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADORA1,AK2,AMH,APOC1,PPFIA3,ATM,NRP2,KSR1,CD86,ARHGEF2,CHRNA4,SULT4A1,COL9A3,MAGI2,DSCAM,EFNA3,EGR3,SORBS3,IGSF6,DLC1,FGFR1,PDLIM5,FYB1,POLL,SPACA9,GRM8,PTGDR2,IL6ST,INPP5B,KCNH2,KCNN1,KIF5A,PALM,GPR85,CRTAC1,EMID1,SNCA,EMC1,ZC3H13,TAL1,TRIM2,GPR161,R3HDM1,TRO,ZMYND8,ADAMTS9,SEMA3B,NAV2" Drug 3938_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ACTN2,AP2A2,AK2,C1QTNF3,LTBP4,MRTFA,ATM,BCL2L2,CFLAR,CFAP410,RCHY1,CPS1,HP1BP3,DRD1,VPS13B,FHL1,DLL3,GLS,GNG4,GPER1,GRIK5,RASSF8,IL6ST,KCNMA1,KCNN1,KCNN2,ADAM22,NELL2,PCDHGC3,PDE1C,PFKFB2,PPP2R2B,MAPK8,PLPPR1,FAM120C,ZDHHC14,FNDC3A,FAM214B,MAPKBP1,KIF13A,DOP1A,PEG10,POPDC3,KIAA1107,TCF7,TRPC1,WIPF1,SPHK2" Drug 5315_DN Danazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "BRAP,ALAD,PPFIA1,APP,ARRB2,NCOA1,ADAM15,NIPBL,C2CD2,CREM,APPL1,RUBCN,ZNF337,EXOG,PLEKHA1,ANKFY1,TRMO,FAM49B,SEPT9,MSL3,GPR37,NR3C1,RNFT2,KIF5C,MYO9A,PCDH9,PMS2,PRKACB,PKIA,SYTL2,MCMBP,SMTN,SLC15A2,INTS9,RCOR3,SP2,ZSWIM8,CLASP2,TACC1,PJA1,EXOC7,AGTPBP1,TCF7L2,UBTF,VGF,NSD2,ZNF184,TFIP11" Drug 3747_UP Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "AP2A2,TRMT9B,ARHGDIG,CDK13,ADAM23,KALRN,CDO1,ZFYVE9,SULT4A1,ERC2,DYRK1A,ABCC9,EFNB3,MRNIP,NCALD,FABP7,OLFM1,ACTL6B,CAMSAP1,RAB30,GNAO1,ADAMTS13,KCNN1,MAN2A2,MBP,ADAM11,MMP17,ADAM22,MT1M,LYRM9,NPTX1,ENPP2,MAPK10,PTPRD,KCNIP1,SH3BP2,DOCK10,PKNOX2,FAIM2,MYT1L,KIF21B,IZUMO4,TF,TLR4,AMACR,TRO,ZIC3,KCNAB1" Drug 3910_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "BRAP,LTBP4,BIN1,SEMA7A,CDK13,CANX,HIP1R,MAGI1,SOCS6,LHX2,PLAA,STOML1,RIMS2,CTIF,SUGP2,DLL3,GAD1,ERAP1,GCNT2,RUNDC3A,ICA1,VWA5A,MAP2,NF1,CNOT4,NPR2,NUMA1,LRP12,PRKAR1B,MAPK8,CNNM2,NKAIN1,SH3BP2,FERMT1,SHANK2,LIMCH1,SNCA,LHPP,VAMP1,VPS13A,KIAA1107,WSCD1,RPGRIP1L,ARHGEF12,HEY1,DAAM2,PARD3,PLPPR2" Drug 2626_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "MRTFA,PLA2G4C,CA4,HIP1R,CHN2,ZFYVE9,NRG2,ATRNL1,PDE4DIP,RIMS2,MFAP3L,DUSP9,SIDT2,DMTN,ZNF589,CAMSAP1,GAB1,TMEM8B,RUNDC3A,GRIK1,HTR5A,KIT,LMO2,AFF1,NOS1,POU3F4,MINDY2,CNTLN,PTPRD,RAP1GAP,ZMAT4,GSTCD,FAM214B,BTBD7,SLN,SPTAN1,IQSEC2,ST5,AJAP1,PLCB1,EXOC7,PSD3,SLC44A1,METTL3,TRPC1,TRPM2,NDRG4,FAM13C" Drug 6101_DN Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "GAS7,NUMB,CADM3,GYG2,ZFYVE9,CNTN1,CRY2,CSF1R,SDC3,DTNA,HIPK3,VPS13B,FAM198B,KIAA1109,FHL1,GNAS,CNTRL,RASSF8,ELOVL5,INPP5B,MAPT,TM6SF1,ADAM22,NUMA1,PLCD1,SLC25A23,RALGDS,FAM184A,SBF1,ZNF821,SNCA,KIF13A,ZCCHC24,EMC1,KDM4C,IQSEC2,PHLDB1,VPS13A,PLCB1,PSD3,ARHGEF12,TGFBR3,ZNF34,CDK20,VLDLR,WIPF1,SF1,GAN" Drug 834_UP 5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "CDC42BPA,ANK3,FAM131A,PPFIA3,CDC14B,ST3GAL5,SCAPER,ZFYVE9,FADS2,CREM,LRIG1,PDE4DIP,CTH,ARHGEF4,EDRF1,DNAJC6,MFAP3L,EFNA3,CELSR3,IRAK4,EN2,ENO2,ARMCX1,GPR153,SRCAP,AHDC1,GNG4,NR3C1,BTN2A1,KCNK1,GIT1,LYRM9,MYO6,PRPH,RALGDS,MORC4,RNASEL,ROBO1,FNDC3A,NLGN1,ZNF365,ZKSCAN3,THSD1,KIAA0930,TK2,WBP2,EPM2A,SSPN" Drug 4399_DN Ethamsylate [2624-44-4]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ARID1A,ALCAM,MRTFA,APOC1,PLA2G4C,CADM3,CFLAR,CDC42,DNAJB5,WHRN,AKAP12,CNTNAP2,SPOCK2,MFAP3L,EDNRA,CNNM1,FGF12,FOXG1,SYT17,GNG4,TJAP1,IL6R,KCNN1,KIT,KPNA5,MAP4,KITLG,ADAM22,NEUROD1,RETREG1,PPARA,RAB3A,RNASEL,TCP11L1,EMC1,IQSEC2,AJAP1,ROBO3,EXOC7,SMG6,WSCD1,TCF7,HIRA,ZIC3,SYNC,EMSY,PRDM2,SLC17A7" Drug 3875_DN Quinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ASIC1,AP2A2,KCNAB2,APP,ARRB1,SLC4A4,CFLAR,CLGN,NCOR2,CSNK1E,SIPA1L1,PARD6A,DMPK,SLC12A6,DUSP9,ZNF589,FER,KIAA1109,FGF12,FHL1,GLYR1,GLS,MAP2,KITLG,MMP17,NEK1,NF1,NUMA1,PIK3CD,PLCD1,TNPO2,FAM120C,RAB3A,GSTCD,WDTC1,IQSEC2,MAPK8IP3,ARHGEF9,KIAA1107,CHST8,ZNF34,TK2,KCNK12,ZFP37,ZIC3,SYNC,ITM2C,SENP7" Drug 1478_DN Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "FAM131A,ARRB1,CFLAR,BTRC,KYAT1,TAOK2,VAX2,HOMER3,MICAL2,DZIP3,TRAPPC9,DTNA,HIPK3,SIDT2,SUGP2,IRAK4,FKTN,KAT8,ZNF589,FAM49B,NCKAP1,KCNJ3,CNOT4,NPR2,SLC11A2,MED1,PRPH,APTX,SBF1,ATXN1,BTBD7,MAPKBP1,KDM4B,EMC1,CEP68,EXOC7,TCF7L2,AHCYL2,ZNF34,BEX4,PARD3,HIRA,ZNF74,TFIP11,MAP3K12,SEMA3B,EPM2A,NUP214" Drug 3199_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "KIDINS220,ALK,APOC1,CACNA1D,HAP1,NEURL1,CHM,TMEM59L,CSF1,CNTNAP2,SNPH,HDAC4,SV2B,SLC12A6,EFNB3,ERBB2,PTK2B,OLFM1,AGAP2,FLNC,PDLIM5,OGA,HRH3,ATXN2L,KCNH2,KCNJ4,KIT,TAGLN3,NOVA2,PALM,GPR85,PGAM2,GDAP1L1,SPATA6,MAPK8,PRPH,RPS6KA2,EPN2,OGDHL,CDK19,NPAS3,CLSTN2,R3HDM1,PIK3R5,AMACR,TRO,FAM155A,PRDM2" Drug 2515_DN Hexestrol [84-16-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "MRTFA,MAP4K3,APBB2,NCOA1,ADAM23,CD86,TPP1,QKI,RCHY1,BAG4,SLITRK5,CX3CR1,DBT,RCAN1,DTNA,FAM13A,ENO2,MTSS1L,ST3GAL6,ZNF589,CSPG5,GAA,INPP5K,LILRA2,LPAR4,GRM8,TJAP1,JAK2,MAP4,MYT1,PIK3CD,RAD52,ZCWPW1,GSTCD,SLC6A8,CCDC88A,SNCA,TMCC1,KDM4C,TCF7L2,TMPO,TNS1,TPD52,FLRT2,VIPR2,NSD2,LAMP5,WIPF2" Drug 3774_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "MTUS1,ALDH7A1,NRP2,SYNJ2,ARHGEF7,CFAP410,CBS,NEURL1,CHM,CHN2,B4GALT6,DNAJB5,LY86,AKAP5,ABI3BP,VCAN,CNTNAP2,SLITRK5,DAPK3,CTIF,EXOG,FCF1,EGFR,ETV1,ANKFY1,PDLIM5,SEPT9,PRRC2B,ELOVL5,HNMT,SCIN,NUMA1,STRN3,PRPH,SNRK,ZSCAN32,ENOX1,NEK11,IL17RB,SLC6A9,SLC9A5,ZNF415,PEG10,CEP68,KIAA1107,TNS1,REEP1,PHTF2" Drug 4379_UP CP-320650-01 [172079-28-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADORA1,MARK4,N4BP2L1,SLC16A4,CDH2,SULT4A1,AKAP5,CREM,DCAF4,NOS1AP,CTIF,CNIH3,SRGAP3,EN2,ETV1,KIAA1109,FYB1,GAD2,RND1,GRM3,SHISAL1,C2orf72,CD200,MYT1,FXYD7,SLCO1C1,NTRK3,KCNK10,PCDHGC3,TMOD2,PLCD1,PLTP,PPARA,CEP41,TTLL7,TMEM206,RPS6KA2,KCNIP1,SLC6A9,SPART,VAMP1,THBS4,R3HDM1,TRIO,HIRA,UCHL1,WIPF1,SLC30A3" Drug 1532_DN Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "PLA2G6,MRTFA,CDC42BPA,APBB2,PPFIA3,ARHGDIG,SLC4A4,KIF1A,CFLAR,ST3GAL5,MTMR2,CBFA2T2,SRSF11,FAM189A2,CREM,DCAF8,TBC1D5,DAPK3,TOM1,HIPK3,EGFR,DENND4A,FER,FGFR1,BAIAP2,AHDC1,CRCP,RAB30,TJAP1,INPP5B,MBD1,MIA2,NEK1,ZCWPW1,NEK11,MCMBP,TCP11L1,ZNF821,SPTAN1,CDK19,MAPK8IP3,PLCB1,ATP11A,NPL,ZMYND8,PLPPR2,HPS4,ACTR3B" Drug 2791_DN Salsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "NDRG2,ANK3,APBB2,APOC1,PPP4R4,ARHGDIG,MARK4,ALDH4A1,ATM,CFLAR,CACNA1D,CHM,PLEKHB1,HOMER3,CSF1R,EDRF1,JAKMIP2,LYPD1,EXOG,DSCAM,PLEKHO1,KIAA1109,FAM49B,TPK1,GLYR1,RASSF8,JAK2,LMO2,ADAM22,NUMA1,PDE3B,PMS2,CEP41,TMEM104,CEP97,TRA2B,SLC1A7,SMTN,FAM214B,COA1,EMC1,THSD1,ATP11A,TGFBR3,TIAM1,TK2,TMOD1,TPM1" Drug 4198_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "MTUS1,PLA2G6,TRMT9B,APC,ARHGAP22,DNAJB5,RGS6,ARHGEF10,CSNK1E,CNTNAP2,RIMS3,BRINP1,RUSC2,C2CD2L,SGSM2,ATN1,MBNL2,MTSS1L,ZNF391,ZNF589,FGFR1,FYB1,SEPT9,GRIK2,GRM1,SOX21,KPNA5,MAPT,MGAT3,ENPP2,RETREG1,PMS2,PTPRB,PID1,KHDRBS2,TTLL7,SBF1,FRMPD1,ZNF667,SOX2,SPATA7,VAMP1,ASTN2,TCF4,TMEM121,TIAM1,OSBP2,VIPR2" Drug CID000220461 NSC3260 Stitch 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "SERPINA3,ANXA7,DYNLL1,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ADAM15,CALM1,RHBDL1,LRBA,MYL6B,CHD1L,SEZ6L2,EGFR,ACTL6B,FOLH1,ATP2C1,RND1,GRIA1,GRIA2,GRIA4,GSN,WIF1,MYLK2,MBD1,MSR1,MYL3,PCMT1,SERPINE2,PKM,PSAT1,PRKACB,RNASEL,RYR1,RYR3,SUPT20H,MLC1,ACTR6,TNNT1,TPM1,TPM2,TPM3,TPM4,AMACR,TMEFF2,RPRM,NUP214" Drug 6796_DN Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "NME5,ALCAM,APBB2,PLA2G4C,SCAPER,CACNA2D2,SLIT2,TPP1,PPP6R2,EDRF1,MFAP3L,SMG7,TOM1,SORBS3,FAM198B,SCML2,ZNF589,BAIAP2,PDLIM5,HBS1L,SRCAP,GLYR1,GNG4,INPP1,INPP5B,NNAT,PDPK1,PRODH,TMEM104,ZSCAN32,PEX5,CEP97,RGS3,PAQR6,ZNF821,BTBD7,ZCCHC24,TSNAXIP1,EMC1,ZBTB43,FAM168A,VAMP1,TNS2,AHCYL2,BHLHB9,VGF,FIP1L1,PHTF2" Drug 4284_DN Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABR,ARID1A,C1QTNF1,CDK10,PDXK,ARRB2,ATM,CFLAR,C5,HIP1R,KIAA1549L,WHRN,PDE4DIP,SDC3,PHF14,DBN1,DCTN1,SORBS3,COQ7,TESK2,BAIAP2,ANKFY1,FYN,DENND2A,SEPT9,INPP5K,SHISAL1,MDFI,TAGLN3,NUCB1,OGDH,NLE1,BCAS3,SH3TC2,CCDC25,MAPK12,SMTN,SLC20A2,SEPT8,KIAA0930,TCF7L2,TMEM121,KCTD2,UBTF,MICAL1,WNK1,KCNAB1,AAAS" Drug 445_UP diclofenac sodium; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "KDM5D,ANK1,APC,AQP6,BRINP2,RASL11B,BMP7,LDLRAD4,CD86,NEURL1,MAGI1,NRXN1,RIMS2,SNPH,EYA1,BAIAP2,FGR,DENND2A,GAD2,C1QL1,BTN2A1,HMX1,HTR2A,VWA5A,LSS,MMP17,ADAM22,MX1,NOVA2,NPR2,RC3H2,PRKAR1B,MTMR10,ACSM5,ASAP3,DZIP1,SLA,SLC1A2,PKNOX2,ELMO2,ZC3H13,SPART,SYT11,PLCB1,SYT5,TCF7L2,AHCYL2,THRA" Drug 4428_DN "aspirin, USP; Down 200; 100uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ARID1A,APBB2,MPDZ,BMPR1B,MTMR3,QKI,CREM,AATK,CSNK1E,VCAN,PDE4DIP,SLITRK5,ARHGAP24,EDIL3,HIPK3,FEM1B,CNNM1,IRAK4,ING4,NCALD,EZH1,SYT17,GNG3,CNTRL,RASSF8,ATXN2L,ICA1,KITLG,MT1M,NF1,NPR2,PLCB2,RAB3IL1,KCTD17,TTLL7,SELL,CCDC88A,COA1,BEX1,SPTB,IQSEC2,SEMA4A,ZEB1,TSN,MICAL1,XRCC4,EPM2A,PHTF2" Drug 908_DN 5140203; Down 200; 15uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ACTN1,MARK4,MPDZ,SOCS6,PLEKHB1,LRIG1,INTS1,SMG7,EFNB3,EPB41L1,SCML2,DLC1,EFCAB2,GPR153,CACFD1,MUM1,MATK,MEIS1,PALM,PDE3B,SSH1,RETREG1,PMP22,LRP12,SIDT1,ELOVL2,PTPRG,PEX5,CEP97,RGS10,RPS6KA2,SBF1,EPN2,ZHX3,ZBTB43,FCHO1,TACC1,MCF2L,TRIM2,THRA,CABIN1,CDK20,HIRA,LMF1,NAV2,MPPE1,ACTR3B,TIGD6" Drug 1815_UP Sulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "NDRG3,BIN1,PPFIA1,KCNAB2,ASPH,ALDH4A1,ATM,ADGRB2,CFLAR,BTRC,CDH2,ZMYM4,CNOT8,AKAP7,CHD1L,PREPL,SPOCK3,E2F5,FCF1,SIDT2,APH1A,USPL1,ETV1,TESK2,USP21,DLL3,OGA,ARFIP1,C1QL1,ATXN2L,INPP5B,MBNL1,ZFYVE21,CNNM2,RAP1GDS1,SS18,SYN2,KAZN,TRIM2,TNS2,SLC35G2,TMEM121,RBFOX2,TPD52,METTL3,TRIO,FIP1L1,ST7" Drug 4117_DN Etifenin [63245-28-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "AK2,APBA2,CDK13,PDE8B,ATM,SLC2A11,CFLAR,BMP7,RAB28,EDRF1,HP1BP3,RUSC2,RABGAP1L,SUGP2,ING4,VPS26C,ZNF589,DPYSL4,FAM49B,SEPT9,GPD2,GRB10,SPACA9,RASSF8,KCNH2,KITLG,NOS1,NPR2,MAPK8,SAMD9,PLPPR1,PTHLH,PTN,NKAIN1,RGS12,SH3BP2,ZNF430,SLC15A2,BTBD7,TROVE2,PLCB1,PSD3,ARHGEF12,AP4E1,TPD52,ZMYND8,MICAL1,EMSY" Drug 2770_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "SPARCL1,PPFIA3,ST3GAL5,SYNJ2,CACNA1I,HAP1,SLC16A4,ZFYVE9,SLC4A7,CPS1,SH2B1,CRMP1,PHF14,DBN1,TMCC2,DTNA,CNNM1,SIDT2,EFNA3,LRRC23,ZNF589,GAB1,GCNT2,GPM6B,STON1,CNTRL,GRB10,TJAP1,MAP4,PLTP,POU3F2,PPP3CC,PPP5C,PRKCB,RPS6KA2,SLC2A5,BTBD7,CXXC4,LIMCH1,TSNAXIP1,HECW1,TBCEL,TCF7L2,SZT2,PCDHA5,SEZ6L,LMF1,NT5M" Drug 7201_UP Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABHD6,BIN1,GAS7,PPFIA3,MARK4,ALDH4A1,ALDH7A1,SCARB1,MAGI1,LHX2,RAB28,QKI,AKAP12,GIT2,LYPD1,SMG7,DSCAM,RCAN1,OPTN,MBNL2,COQ7,DENND4A,CDKL3,F3,F8,FGFR1,FHL1,COPS8,GLYR1,CACFD1,TJAP1,KCNK1,PCDH9,STRN3,MAPK8,SAMD9,WLS,ZFP30,RAB3GAP1,SNCA,WDTC1,ZCCHC24,KDM4C,NSFL1C,TPD52,VIPR2,CLDND1,SEMA3B" Drug 3470_DN Securinine [5610-40-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ASPHD1,APBB2,PPFIA3,SYNJ2,CFAP410,RAB26,CRY2,CSNK1E,PDE4DIP,FAM169A,HDAC4,KIAA0513,RIMS3,C2CD2L,PARD6A,SGSM2,DTNA,SORBS3,EZH1,F8,ZNF589,INPP5K,NR3C1,MUM1,PADI2,SLC11A2,RETREG1,RETREG2,PKIA,PEX5,NKAIN1,RALGDS,FOXRED2,MAPK12,ATXN1,ZKSCAN3,SMARCC2,ELOVL4,TACC1,SEMA4A,IQCE,KCTD2,TPM1,CDK20,LMF1,XRCC4,NDRG4,MAP3K12" Drug 4607_DN Dimethadione [695-53-4]; Down 200; 31uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "MTUS1,MRTFA,SHROOM2,MADD,ASPH,SYNJ2,SCAPER,MAP7,CDH2,TAOK2,CLU,FADS2,RAB26,BAG4,CTNND2,ZNF337,ING4,TUBD1,EPHA5,TUBB4A,ZNF589,ANKFY1,TRMO,USP21,GPER1,GRIK2,CACFD1,NR3C1,KHK,KIF5C,NASP,NFYA,PLCD1,PLXNB1,PPP5C,RALGDS,SLC1A7,ELMO2,TNIK,ZBTB43,TAB2,FBXW11,TRIM2,AHCYL2,SMUG1,NSD2,NDRG4,SH3GLB2" Drug 541_UP Iressa; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADORA2A,APBB2,ARRB2,ATP2B2,SYNJ2,CARS,DLGAP1,CHN2,CHRM4,ZFYVE9,STOML1,FAM189A2,CTH,ECE2,SPOCK2,C2CD2L,SMG7,SGK2,EFNB3,ING4,PTK2B,SCML2,TESK2,ZNF589,FYN,ERAP1,PCSK1N,GRB10,NXPH3,INPP5B,NTRK3,P2RX7,PLCD1,CCDC40,GAL3ST4,ST6GAL1,KIF21B,ZSWIM8,CDK19,SPART,SRPK2,SSTR2,SEMA4A,PHF24,KAT6B,VGF,VLDLR,SLC38A1" Drug 6417_DN CGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "AP2A2,TRMT9B,APC,PPFIA3,ALDH7A1,CBFA2T2,RCBTB2,RAB28,TPP1,SULT4A1,RAB26,CRY2,CNTNAP2,SLITRK5,SPOCK2,PDLIM5,TRAF3IP2,DISC1,SRCAP,C1QL1,GNG4,ELOVL5,ADAM22,ZNF862,NPR2,FSD1,MAPK7,PTCH1,RAB3A,RGS10,TRAPPC13,SBF1,FBXO11,SLC20A2,KDM4B,SPTB,DDN,VPS13A,TMEM121,CABIN1,OSBP2,PLPPR2,WNT7A,KLC2,XRCC4,SEMA3B,KCNAB1,NUP214" Drug 3137_DN Tiletamine hydrochloride; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "NDRG3,BIN1,CDK13,MTMR3,CACNA1A,SOCS6,DNAJB5,CSNK1E,SIPA1L1,SLITRK5,SPOCK2,OLIG2,LRRC23,GAA,GPM6B,GRM1,IL11RA,MBNL1,GIT1,MX1,ZNF862,OGG1,PDE4D,PLCD1,PLEC,SLC25A23,PMP22,CNNM2,BEND5,ZDHHC14,MYH14,GSTCD,FAM214B,TMCC1,TNIK,DBNDD2,NCDN,STX1A,KAZN,DNMBP,CAMSAP2,TCF7L2,TMOD1,PARD3,RBFOX2,MKRN3,LAMP5,FZD3" Drug 843_DN 5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "SLC12A5,AP1B1,MTUS1,BIN1,OGT,CDC42BPA,APC,SYNJ2,SPAG9,B4GALT6,QKI,LYPD1,PARD6A,G3BP2,EFNB3,EGR3,COQ7,MTSS1L,CDKL3,RACK1,ST3GAL6,TRMO,SEPT9,GART,GHR,SPIN1,GPER1,IDH3B,KCNJ3,CNOT4,PC,PIK3R1,STRN3,PRKAB2,PLEKHB2,RALGDS,RET,SYT1,SEMA4A,TIAM1,BEX4,CDK20,TRIO,HIRA,RPRM,ZNF45,PRDM2,MPPE1" Drug 5969_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "DPF1,ACTN2,TRMT9B,APAF1,PPP4R4,SCAPER,CACNA2D1,SYNGR3,NEURL1,TCEAL2,CSNK1E,CNTNAP2,DZIP3,ATN1,DTNB,TOM1,CNNM1,ELN,KCNMB2,PIPOX,DLC1,KIAA1109,FGFR1,CAMSAP1,GABRA2,GPM6A,STON1,CNTRL,TJAP1,KCNN1,MT1M,PIK3CD,MAPK10,PTAFR,KCTD17,RPS6KA2,CPEB3,CNKSR2,FAM214B,MYH15,SYN2,IQCE,PCDHA5,THRA,TK2,VGF,KCNK12,NT5M" Drug 7022_UP Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADD2,ADRB2,MRTFA,APBB2,ARHGDIG,SYNJ2,TAOK2,SLC4A7,SH2B1,PDE4DIP,ARHGEF4,KIAA0513,TRAPPC9,DTNA,OPTN,EFNB3,EGFR,EGR3,MTSS1L,ZNF589,KIAA1109,PRKAG2,AFF2,DPYSL4,NEU3,TXNL4A,ELOVL5,KIF5C,IPO5,MAP4,LYRM9,NF1,PDE3B,PEX5,RAD52,NLGN1,FAM214B,RBM34,ERC1,AJAP1,PLCB1,EXOC7,PLPPR2,KCNK12,ZNF24,ZNF45,LRP8,SEMA3B" Drug 2741_DN Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABHD6,MTUS1,PKP4,PPP4R4,ARRB1,SYNJ1,FUBP1,SLC16A4,SCARB1,FOXN3,CHM,EPS15L1,CREM,CSF1,DZIP3,USP6NL,HDAC9,DAPK3,E2F5,NCALD,RRAGB,KAT8,ZNF589,FGFR1,FHL1,CAP2,NBEA,DISC1,WASF3,LILRA2,IL6ST,MDM4,MEF2C,NNAT,SERPINE2,CCSER2,POU6F1,MINDY2,PTCH1,RIPOR1,RGS3,SCG5,STX1A,ATP11A,ADGRL3,KIAA1107,TCF4,CRTC1" Drug 6255_DN Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABAT,ASPHD1,MTUS1,CDK10,BMP7,CHN1,CNOT8,TMEM184B,GIT2,MED24,RHOBTB1,DNM1,NR1D2,ERBB2,F3,CINP,SYT17,SRCAP,COPS8,NR3C1,ICA1,DIPK1A,NCAM2,CNOT4,CCSER2,SMIM7,FSD1,PTK2,RIPOR1,TMEM231,MSANTD2,SEC61A2,CCDC25,MCMBP,SAFB,SFPQ,KBTBD4,SMARCC2,TMCC1,POGZ,NXT2,ANKRD12,TRIM2,CLASP1,TIAM1,RPRM,MVB12B,RNF146" Drug 4531_UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ACHE,SYT13,CDC42BPA,ADAM23,CFLAR,CAMK2B,RUNX1T1,SEPT7,PCYT1B,CRY2,RIPOR2,RIMS3,SPOCK3,AK5,SIDT2,CEND1,F5,DCTN2,SYT17,GPR22,GPER1,GRM8,GSN,HLF,DIPK1A,JAK2,MMP16,NCAM1,NEFM,PDE3B,PDE4D,PLCB2,PTPRN2,NEK11,SCN8A,KANSL3,SLC11A1,DOP1A,TNIK,SYT11,VAMP1,ADGRL3,TIMP4,SSBP2,LAT2,SH3GLB2,PRDM2,MVB12B" Drug 2234_DN Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ARID1A,APBA2,APC,APOC1,ARRB1,ALDH4A1,ATM,BCL7A,CAMK2G,ARHGAP33,FOXN3,ZFYVE9,CSF1R,SDC3,SEC14L5,CTIF,ING4,DMTN,EZH1,FER,FGFR1,CGREF1,INPP5K,GCNT2,POLL,GRIK5,CACFD1,INPP1,TM6SF1,MYO7A,PALM,PDE3B,LRRC49,RGS10,RGS12,ANKRD6,FAM214B,BTBD7,MAPKBP1,SOX3,TTBK2,KAZN,CHST8,TMOD1,RUNDC3B,LMF1,SYNC,PRDM2" Drug 3525_DN Mecamylamine hydrochloride [826-39-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "KIDINS220,AP1B1,AMPD3,CDK10,MARK4,ALDH4A1,ATM,CFLAR,SYNJ2,CFAP410,TMEM184B,CSF1,FAM169A,DAPK3,RUSC2,SMG7,SIDT2,EGFR,ENO2,MSL3,STON1,CNTRL,NR3C1,MAN1B1,INPP1,KHK,IPO5,GIT1,NPTX1,PCDH9,PLXNB1,PTPRE,TMEM231,SMTN,CDK5RAP2,WDTC1,SPTAN1,MAPK8IP3,STX1A,AJAP1,ASTN2,ATP11A,TCF7,AP4E1,TK2,CABIN1,WNK1,MAP3K12" Drug 333_DN diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABR,BRAP,ANK3,GAS7,ARRB2,SYNJ2,BAIAP3,CA12,HIP1R,LARGE1,ADGRG1,CHRM4,PCYT1B,NCOR2,DNM2,ATN1,DNAJB6,TNK2,SRPK3,EPB41L1,LRRC23,ERCC2,BAIAP2,FLNC,SEPT9,LILRA2,FAM107A,ATXN2L,L1CAM,MAP4,GIT1,MYL3,MYO6,NNAT,OPCML,CCSER2,NLE1,PLEC,POLG,RIPOR1,SYNDIG1,FOXRED2,ITSN1,CDK5RAP2,DOP1A,ZBTB43,KCTD2,PMEPA1" Drug 2255_DN Pentylenetetrazole [54-95-5]; Down 200; 29uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "NDRG2,AP2A2,BEGAIN,AMPD3,BIN1,AMT,GAS7,ASPH,RASL11B,ATP6V0A1,SYNJ1,GYG2,BTRC,CFAP410,FADS2,HOMER3,BAG4,EDRF1,TOM1,EGFR,DMTN,LRRC23,FGF12,FHL1,SRCAP,GLYR1,POLL,GNG3,GRB10,NR3C1,KCNN2,TM6SF1,SERPINE2,MAPK7,ZDHHC14,RGS3,RNASEL,WLS,SH3BP2,SLC22A4,RBM34,PLCB1,ZNF34,TMOD1,CABIN1,KCNK12,SLC30A3,KCNAB1" Drug 2156_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABR,NDRG3,NDRG2,APBB2,N4BP2L1,RIPK1,BACH1,SPAG9,CNOT8,CHD1L,DGKG,RCAN1,EFNA3,ABI2,EPB41L2,RASGRP2,ZNF589,KIAA1109,PDLIM5,TRAF3IP2,ZMYND11,HMGCR,HSF2,KPNA5,LSS,NF1,NFYA,OCRL,ENPP2,SERPINE2,CCSER2,MINDY2,PKN2,RASA3,SLC2A5,SLC11A1,KDM4B,TROVE2,NXT2,MAPK8IP3,NSFL1C,DNMBP,TBL1X,TCF4,ZEB1,THRA,TMOD1,ST7" Drug 2940_UP Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABHD6,PDE8B,KSR1,LDLRAD4,BTRC,RUNX1T1,RAB28,NRXN3,CLU,DNAJB5,CNTN1,SIPA1L1,CTNND1,SEC14L5,DBT,DNAJC6,CDON,EDNRA,HEYL,FAM13A,ELN,RASGRP2,FCGRT,SORBS1,KHDRBS3,ALDH1L1,GLRB,GNG4,GPM6B,SPACA9,GRM1,ATXN2L,SCAMP5,MYO6,P2RY1,TREM2,TCP11L1,SCG5,SLC1A2,SLC11A1,BTBD7,WDTC1,IZUMO4,TNS2,TJP1,TRH,KCNE5,KCNAB1" Drug 7451_DN Triflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ABR,AK2,PKP4,ALDH4A1,ATM,CAMK2G,SPAG9,CBFA2T2,FOXN3,ZFYVE16,RIMS3,C2CD2L,MAMLD1,FEM1B,CELSR3,SUGP2,BAIAP2,CAMSAP1,GPR153,B4GALNT1,SEPT9,AHDC1,BTN2A1,DIPK1A,MBD1,NCAM2,NEK1,NF1,ODF2,CNNM2,RIPOR1,FUZ,PEX26,EPN2,CDK5RAP2,MAPKBP1,KDM4B,SOX3,SPTAN1,LHPP,FCHO1,HIRA,UBTF,LMF1,XRCC4,EMSY,GDPD5,ACTR3B" Drug 3529_UP Lansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "TRMT9B,APBB2,DNAH17,CADM3,CACNA1I,CBFA2T2,ARHGEF2,FOXN3,CHM,SLIT2,TMEM59L,FADS2,AKAP7,NCOR2,SDC3,CTIF,FABP7,ST3GAL6,ZNF589,IQCG,RND1,GPD2,GPM6A,GPM6B,IL6R,KCNN1,KPNA5,MSI1,OPRL1,DUSP26,PLEC,PPP5C,MAPK8,RAB3IL1,RGR,SLC1A7,SMARCD3,HECW1,TROVE2,ST5,MAPK8IP3,PLCB1,PCDHGB6,PCDHGA10,ICAM5,HEY2,TRIO,ZIC3" Drug 3282_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.19E-04 1.00E+00 5.95E-03 6.77E-02 48 195 "ADORA2A,KIDINS220,AP2A2,C1QTNF3,AMPD3,APBB2,PDXK,ARRB2,DNAH17,ASPH,ALDH4A1,ATP6V0A1,BAIAP3,HAP1,CRY2,RIMS3,KIAA0586,SIDT2,ELAVL3,F3,DLC1,FOLR2,ALDH1L1,INPP1,LMO2,ZNF862,NUCB1,NUMA1,OGDH,CLDN11,PALM,C1orf54,ZNF365,FAM214B,KDM4B,TSPYL2,TROVE2,CAMTA2,VAMP1,SMG6,PCDHGA1,TMOD1,ZMYND8,FAM155A,VIPR2,WIPF1,KLC2,SPHK2" Drug CID000451435 AC1L9PN4 Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "CALB1,ENO2,MBP,NEFM,NEFH,RET" Drug ctd:C459562 "L-826,141" CTD 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "PDE8B,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D" Drug CID000016247 aminocarb Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "ACHE,AMH,BCHE,KCNMA1,DNMBP,TUBA1A" Drug CID000017517 isoprocarb Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "ACHE,APBB1,BCHE,CLTC,FXYD1,PBRM1" Drug ctd:D010095 Oxotremorine CTD 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "ACHE,CHGA,CHGB,EDN1,NPY,SCG2" Drug DB00829 Diazepam Drug Bank 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "GABRA1,GABRA2,GABRA3,GABRA5,GABRB1,GABRB3" Drug CID000520075 vinyl sulfonamide Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "EDN1,EDN3,EDNRA,EDNRB,EGFR,ERBB2" Drug CID000181428 FK960 Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "ACHE,BCHE,MAPK9,MAPK10,SLC1A2,SST" Drug CID000194954 Hexapeptide 4 Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "B3GAT1,MCHR1,SST,SSTR1,SSTR2,TACR1" Drug CID004014619 AC1N21PP Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID005311462 mM PEP Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug ctd:C035964 trequinsin CTD 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "PDE8B,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D" Drug CID000107216 "1,3-cyclopentanedicarboxylic acid" Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID000175064 LY97241 Stitch 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "KCNA1,KCNA2,KCNA4,KCND2,KCNH1,KCNH2" Drug ctd:D005702 Galantamine CTD 8.21E-04 1.00E+00 5.95E-03 6.77E-02 6 9 "ACHE,APP,BCHE,CHRM1,CHRNA4,CHRNB2" Drug 5602_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.23E-04 1.00E+00 5.97E-03 6.79E-02 47 190 "ACTN1,ARID1A,AGT,APAF1,APBA2,APOC1,ASCL1,GYG2,CFAP410,ZFYVE9,ABCG1,VCAN,PDE4DIP,CTH,GREB1,RASSF2,MFAP3L,DRD1,EDNRA,EFNB3,ING4,MTSS1L,CEND1,AGAP2,GATM,GNAL,GPR19,STON1,GPR37,GRM8,MAN2A2,MIA2,AFF1,AFDN,MOBP,NF1,SLC9A5,TSNAXIP1,CDK19,NPAS3,SPART,PHLDB1,FAM168A,TRIM2,BEX4,XRCC4,SSPN" Drug 3165_UP Retinoic acid [302-79-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.23E-04 1.00E+00 5.97E-03 6.79E-02 47 190 "AMT,OGT,APBA2,GAS7,CDK13,ASTN1,ADAM23,BTRC,CA4,CACNG1,CAST,RUNX1T1,TMEM59L,LY86,SLC4A8,CSF1,KLHL3,C3orf18,EPB41L1,FLT1,GAP43,SOX21,HRH3,PFKFB3,PLP1,PTPRH,RAP1GAP,SCN2B,SELL,SLC6A9,SLC8A1,SHANK2,SLC22A4,FAIM2,HECW1,PLCB1,KAZN,TRIM2,PCDHGB6,TRIO,VSNL1,WIPF1,MKRN3,GDPD5,PRDM10,SEMA3B,HRASLS" Drug 7528_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.23E-04 1.00E+00 5.97E-03 6.79E-02 47 190 "NME5,ANK3,CFLAR,ST3GAL5,IL33,CLCN3,ABI3BP,CREM,PDE4DIP,CNTNAP2,CTH,ARHGAP32,HP1BP3,FBXL5,PARD6A,RCAN1,MBNL2,EPB41L2,STX2,ETV1,FER,GLRB,GPR37,GUCY1B1,KLF12,MYO6,NAP1L2,NOVA1,PLCD1,RC3H2,MAPK7,LRRC49,RGS10,CSRNP3,MRAS,SH3BGR,DOCK10,SHANK2,KBTBD4,ELMO2,KDM4B,SPTAN1,CDK19,NXT2,SSBP2,UBE2H,MPPE1" Drug 5926_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.23E-04 1.00E+00 5.97E-03 6.79E-02 47 190 "ADCY2,ADORA1,MTUS1,CDC42BPA,ARHGDIG,CADM3,CACNA1I,LDLRAD4,CA12,CACNG1,SLC16A4,EPS15L1,GREB1,MFAP3L,DMPK,CDON,ATN1,RASGRP1,EGR3,FGF12,SORBS1,GRIK5,ICA1,KCNF1,PCBP3,NUCB1,KCNK10,PDE4A,PFKFB3,LRP12,MAPK8,GAL3ST4,RET,RGS10,ZFHX4,ROM1,SGK1,PREX2,LIMS2,DOP1A,TSNAXIP1,KAZN,TBCEL,TCF7L2,TRIM2,SZT2,DNALI1" Drug ctd:D013619 Tacrine CTD 8.24E-04 1.00E+00 5.97E-03 6.79E-02 18 53 "ACHE,ADCYAP1R1,BCHE,CHRM1,CHRNA4,CHRNB2,DLG2,GABRA4,ITGAM,KCNH2,KCNN2,MYBPC1,NEUROD1,NOS1,SLC6A1,SNCA,SYN2,SLC47A2" Drug 1585_UP Terbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; HL60; HG-U133A Broad Institute CMAP Up 8.27E-04 1.00E+00 5.99E-03 6.81E-02 46 185 "AP2A2,APBA2,PPFIA3,SEMA4G,ARRB2,CFLAR,CAST,CD86,CD38,CREM,MICAL2,PPP1R16B,DOCK4,FAM13A,PLEKHO1,EPB41L2,BAIAP2,MALT1,RUNDC3A,PRRC2B,CACFD1,CLASRP,ATXN2L,KCNN1,OLR1,CLIP1,SGK1,SH3BP2,FUZ,AMBRA1,SLA,ARHGEF40,CCDC88A,ZSWIM8,BEX1,SPTB,CDK19,TSPYL2,PLCB1,ATP11A,KAT6B,TSN,CADM1,FLRT2,PLPPR2,CLDND1" Drug 5632_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.27E-04 1.00E+00 5.99E-03 6.81E-02 46 185 "NDRG2,APAF1,AQP6,PRX,SLC4A4,CA4,RUNX1T1,SLC16A4,CD86,RGS6,JAKMIP2,DYRK1A,EFNB3,MBNL2,ZNF589,KIAA1109,FGF13,GAB1,SIGLEC8,ATP8A2,GPR162,C1QL1,RND1,SPACA9,GRM7,CELF3,ATXN2L,KCNK2,VWA5A,MMP17,MX1,NPTX2,PCSK5,PLCB2,PILRA,MAPK8,PTAFR,ZNF821,SH3BP2,SLC11A1,SHANK2,SLN,CDK19,ATP10B,TRIM2,PCDHGA10" Drug 6082_UP Tetrandrine [518-34-3]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.27E-04 1.00E+00 5.99E-03 6.81E-02 46 185 "RALGAPA1,SYN3,ACTN2,BEGAIN,BIN1,APOC1,ARHGDIG,PLA2G4C,ATP1A2,BAIAP3,CSF1,HDAC9,RASSF2,ELAVL2,ACSL4,CAMSAP1,AFF2,SRCAP,PRUNE2,GRM2,GRM7,SLC2A6,HMGCR,ICA1,CD200,TAGLN3,MX1,MYH7,NEFM,NOVA2,NPPA,PAH,TREM2,CDK18,SERPINE2,PURG,RGS12,SLC11A1,SLN,KIF21B,INKA2,PHF24,PSD3,PCDHA3,PIK3R5,TRPM2" Drug 1167_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.27E-04 1.00E+00 5.99E-03 6.82E-02 43 170 "GRAMD1B,APBB2,APP,ARNTL,NCOA1,CFLAR,CD86,CREM,SIPA1L1,PPP1R16B,SV2B,EDNRB,EEF1A2,FAM13A,MBNL2,FHL1,CAP2,ANKFY1,AHDC1,LILRA2,MUM1,IL6ST,PDE4B,PDE4D,PMP22,MBOAT7,PRKAB2,PRKACB,MAPK8,TRIM68,TCP11L1,HSPA4L,PEX26,SPTAN1,EXOC7,CAMSAP2,DMXL2,TNS2,TPD52L2,ZMYND8,FLRT2,SF1,ZBTB38" Drug CID000192866 "1,2-diglyceride" Stitch 8.29E-04 1.00E+00 6.00E-03 6.83E-02 44 175 "ABHD6,AGT,DGKZ,GPAM,DGKD,SLC2A11,CCK,DGKI,LGI1,CHRM1,MYL6B,PCYT1B,GAL3ST1,PLCXD3,DGKB,DGKG,EDN1,EDN3,EDNRA,TUBB3,PLCD4,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,KCNH1,MYL3,NRGN,PDPK1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,SMPD3,SLC2A5,PLCB1,TRH,PLPPR5,SCG2,PLD4" Drug CID000010595 lithocholyltaurine Stitch 8.29E-04 1.00E+00 6.00E-03 6.83E-02 44 175 "ABAT,APAF1,CACNA1A,CACNA1B,CRLF1,CLTA,CNR1,HDAC9,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSP90AA1,IGF1,OGG1,PAH,PENK,ABCB1,PACSIN1,PRKCB,PRKCG,PKN2,PRKCZ,PYGM,QDPR,FBXW7,ATXN7,FOXRED1,SLC1A3,SLCO1A2,SNCA,MCF2L,NR2C2,CA10,PRTFDC1,JPH3" Drug CID005195771 1-phenylpentan-3-amine Stitch 8.38E-04 1.00E+00 6.06E-03 6.90E-02 12 29 "CAST,CHGA,ENO2,GFAP,MAP2,MBP,NEFM,NEFH,NPY,PRPH,SYP,UCHL1" Drug CID000125958 SR 95103 Stitch 8.40E-04 1.00E+00 6.08E-03 6.91E-02 8 15 "ABAT,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2" Drug CID000003821 ketamine Stitch 8.40E-04 1.00E+00 6.08E-03 6.92E-02 61 262 "ASIC1,AMT,ARSE,CACNA2D1,ASIC3,CHRNA4,CHRNB2,CNR1,CNTN1,DLG4,GRIN3A,F3,F5,F8,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,TNFAIP8L3,KCNB1,NOS1,NPPA,OPRL1,PENK,MAPK3,KLK6,GSTCD,RYR1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,SPP1,TACR1,TTPA,VSNL1" Drug CID001008511 "1,4-bis-(phenoxyacetyl)piperazine" Stitch 8.59E-04 1.00E+00 6.21E-03 7.07E-02 54 226 "AP1B1,OGT,ATP1A1,STX16,AP1M1,CACNA1E,RUNX1T1,AP4M1,CLTC,SLC32A1,ABCG1,CSNK1E,CSNK1G3,ZFYVE16,HP1BP3,BLOC1S6,SNAP91,ACOT8,PDCD6IP,TOM1,ABI2,ELAVL2,VTI1B,AGAP2,FOLH1,NBEA,PDLIM5,NCKAP1,COPS8,GRB10,GRIK1,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM8,IL12A,LAMP2,LSAMP,NF1,NNAT,RET,S100B,SYP,SYT1,TCF7,TF,P2RY12,SLC30A3,SLC30A4,HPS4,SLC17A7,AP3B2" Drug CID000002185 N-arachidonoylethanolamine Stitch 8.59E-04 1.00E+00 6.21E-03 7.07E-02 54 226 "ASIC1,ABHD6,ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,CACNA1I,CACNA1A,CACNA1B,CACNA1E,CBR1,CBS,CCK,COPB2,FADS2,CNR1,SH2B1,VCAN,EDN1,ENPP6,STX2,FOXM1,HRASLS5,CRCP,GRIK1,GRM5,HTR2A,HTR5A,KCNA1,KCNA2,KCNA4,KCNA6,KCNH2,KCNJ3,KCNK1,KCNK3,PPM1L,CCDC80,NPY,NTRK2,KCNK10,PDE3B,ANLN,FTO,PPARA,MAPK3,MAPK8,MAPK9,MAPK10,EFHD1,ZNF106,PLD4,HRASLS" Drug ctd:D012964 Sodium CTD 8.63E-04 1.00E+00 6.24E-03 7.10E-02 25 84 "ADRB2,AGT,ATP1A1,SLC4A4,CACNA1E,CP,EDN1,EDN3,SLC9B2,FGF13,GRM1,IGF1,KCNH2,KCNK1,NOS1,SCN2A,SCN2B,SCN3A,SCN8A,SCNN1D,SLC6A11,SLC8A1,SLC20A2,SCN3B,SLC17A7" Drug CID000010535 neuroNal Stitch 8.67E-04 1.00E+00 6.27E-03 7.13E-02 17 49 "ASIC2,ASIC1,ACHE,LGI1,CLGN,CHRNA4,CHRNB2,TPP1,TUBB3,LINGO1,TAGLN3,NOS1,NPTX1,NPTX2,OMG,ASIC4,RUSC1" Drug CID003000715 thiopental Stitch 8.79E-04 1.00E+00 6.36E-03 7.23E-02 31 112 "AGT,AK2,APOC2,BCHE,CACNA2D1,BOC,AK5,DMD,TRAPPC9,EDN1,EDN3,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,STON1,IL1RAPL1,TNFAIP8L3,HSP90AA1,PIK3C2A,PRKCB,PRKCG,PKN2,PRKCZ,PYGM,RYR1,RYR3,S100B,ARX" Drug CID000006334 propan Stitch 8.95E-04 1.00E+00 6.47E-03 7.36E-02 13 33 "KDM5D,ATP6V0A1,CDO1,CEP170,DTNA,SDCBP2,DNER,MEST,NPTX1,RAB3IL1,PDZD2,ST5,FTSJ1" Drug CID000017011 Depixol Stitch 8.95E-04 1.00E+00 6.47E-03 7.36E-02 13 33 "ADCY5,ADCY6,ADCY8,CALY,DRD1,ZMYND10,GRIK4,GRIK5,GRIN2C,GRIN2D,KITLG,PDCD2,ABCB1" Drug CID004629888 AC1NDQB9 Stitch 8.95E-04 1.00E+00 6.47E-03 7.36E-02 13 33 "ASCL1,BMPR1B,PNKD,SIRPA,DMPK,DYRK1A,EFS,POLK,GPER1,ZDHHC4,RNASE1,UEVLD,TP53BP2" Drug CID004186342 Ip5I Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "PLA2G6,P2RX6,P2RX7,P2RY1,SYP,SLC17A7,SLC17A6" Drug CID000449117 be-6 Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "LGI1,DCT,EN2,PTK2B,GRB10,PTK2,UBE3A" Drug DB01873 Epothilone D Drug Bank 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB1,TUBA1A" Drug CID000176108 endothall thioanhydride Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "EDNRA,INPP5K,PPM1L,PTPA,PPP3CA,PPP3CC,CABIN1" Drug DB03010 Epothilone B Drug Bank 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "TUBA1B,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB1,TUBA1A" Drug CID001894360 AMN082 Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "STX2,GRIK1,GRM1,GRM2,GRM5,GRM7,GRM8" Drug CID011633167 2ohu Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "IP6K1,LRRC23,IP6K2,IP6K3,HSP90AA1,ITPKA,ITPKB" Drug CID000474412 dGprG2'OMe Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "ATP6V0A1,NRP2,SUMF2,FLT1,NPTX1,NPTX2,EXOSC10" Drug CID000068722 pivoxazepam Stitch 8.98E-04 1.00E+00 6.48E-03 7.37E-02 7 12 "F3,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000176408 SCH 58261 Stitch 9.00E-04 1.00E+00 6.49E-03 7.39E-02 16 45 "ADORA1,ADORA2A,ADORA3,BLOC1S6,DRD1,PPP1R1B,GAD1,GAD2,GFRA1,GRM5,P2RY1,PENK,SLC1A2,SLC1A3,SLC6A1,SYP" Drug CID000446744 AC1L9K1W Stitch 9.00E-04 1.00E+00 6.49E-03 7.39E-02 16 45 "CHM,FKTN,FOLH1,GPM6B,L1CAM,MAG,MBP,MOBP,MOG,NASP,OMG,PLP1,PMP22,POU3F4,ATXN7,GJC2" Drug CID000115201 philanthotoxin Stitch 9.00E-04 1.00E+00 6.49E-03 7.39E-02 16 45 "PLA2G6,CHRNA4,CHRNB2,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,GSN,ZIC3" Drug CID000003843 AC1L1GU8 Stitch 9.13E-04 1.00E+00 6.58E-03 7.49E-02 20 62 "ADORA2A,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ALDH7A1,LRBA,DYRK1A,EDN1,STX2,GUCY1A2,GUCY1B1,IGFBP1,NOS1,NPPA,NPR2,CNTN3,PTPA,PRKACB,MAPK12" Drug CID004473765 AC1NBU2S Stitch 9.14E-04 1.00E+00 6.58E-03 7.49E-02 32 117 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,HAP1,AIFM1,CACNA2D2,CNR1,EDN1,CACNG7,CACNG2,GUCY1A2,GUCY1A1,GUCY1B1,NPPA,NPR2,PKD1,MAPK3,PYGM,RTKN,RYR1,RYR3,SYT1,TRH,VIPR2" Drug CID000004426 AC1L1I54 Stitch 9.20E-04 1.00E+00 6.58E-03 7.49E-02 15 41 "ADCY2,ADCY5,ADCY6,ADCY8,CACNA1A,CACNA1B,CACNA1E,CACNA2D1,SDCBP2,MCHR1,OPRL1,PDYN,PENK,SSTR1,SSTR2" Drug CID000447446 U cm Stitch 9.20E-04 1.00E+00 6.58E-03 7.49E-02 15 41 "ADAR,PDXK,ARHGEF25,CD86,CDC25B,TRIM69,AASS,MALT1,INSM2,GRB10,RAD17,FEZF2,TP53BP1,KCNT2,SLC26A10" Drug CID000082320 1-EBIO Stitch 9.20E-04 1.00E+00 6.58E-03 7.49E-02 14 37 "SLC4A4,CACNA1A,CACNA1B,KCNMB4,KCNMA1,KCNN1,KCNN2,KCNN3,LSS,MAP4,MTR,PRPH,RPS6KA2,PEG10" Drug 4742_DN Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG3,NDRG2,KIDINS220,LTBP4,BIN1,APBA2,GAS7,CDC14B,MARK4,ST3GAL5,WHRN,CSNK1E,CNTNAP2,NOS1AP,DCAF8,MRNIP,HSD17B14,DMTN,ST3GAL6,AFF2,ALDH1L1,GLS,ATXN2L,MAP4,MSI1,ADAM22,ZNF862,NOS1,RETREG1,NLE1,PRKAR1B,RAB3A,RALGDS,ZFHX4,PAQR6,SELL,PEX26,SNCA,UNC5B,ZNF423,MAPK8IP3,ROBO3,SMG6,SZT2,PCDHA5,HIRA,MICAL1,NDRG4" Drug 5636_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABHD6,EP400,APC,GAS7,MARK4,NCOA1,SCAPER,GYG2,BTRC,KYAT1,CBFA2T2,ARHGEF2,ZFYVE9,BAG4,ATRNL1,SIPA1L1,MFAP3L,FBXL5,ING4,F3,ZNF589,BAIAP2,CAMSAP1,NR3C1,RASSF8,KCNH2,KCNJ3,MPP2,PCDH9,PLEC,RETREG2,PRODH,TMEM104,WDR25,ROBO1,NEK11,ABLIM3,SLC20A2,ZHX3,EXOC7,TMEM121,TK2,BHLHB9,PARD3,TPM1,HIRA,SLC17A7,TIGD6" Drug 7316_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "GAS7,ARRB2,KSR1,SYNJ2,MYRF,CHN2,TAOK2,ZFYVE9,DNAJB5,WHRN,CSF1,VCAN,CNTNAP2,RHOBTB1,EFNB3,ELAVL2,DLC1,FOXG1,FLT1,DENND2A,SYT17,ELOVL5,IFI16,INPP5B,KCNC1,KHK,CNOT4,PALM,PDE4D,MAPK8,PAQR6,DOCK10,DZIP1,PEX26,SLC15A2,SLC20A2,SNCA,TMCC1,TNIK,PEG10,SAMSN1,THSD1,CEP68,VAMP1,KAZN,TIAM1,TK2,TRPC1" Drug 2717_UP Ebselen [60940-34-3]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADD2,BIN1,MPDZ,CFAP410,CACNA2D1,CDO1,RAB26,SIPA1L1,CHD5,RIMS2,DBT,MFAP3L,MAMLD1,SORBS3,RASGRP2,FGFR1,PRELID3A,B3GAT1,GABRA5,GALC,AP4S1,BACH2,SCRG1,HTR2A,KCNJ3,KCNJ4,MPP2,MSR1,MX1,OGG1,OXTR,POU3F2,CEP41,GAL3ST4,RGS10,RNASE1,PKNOX2,LIMCH1,PALLD,SYT5,DNMBP,IQCE,TCF4,DNAH7,BEX4,FLRT1,ST7,PAK5" Drug 6923_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADORA2A,ADRA1D,BIN1,DNAH17,ATP2A2,MFAP3L,HP1BP3,NR1D2,ATN1,EFNA3,EIF4G2,PLEKHO1,EPB41L2,CAMSAP1,ZNF44,ALDH1L1,NR3C1,ATXN2L,SYNPO,IRF8,MAP2,MBNL1,MDFI,MEF2C,MITF,ADAM22,NEFM,NUMA1,ENPP2,PROX1,PTHLH,FAM120C,FAM184A,RGS12,SBF1,CCDC88A,BTBD7,ZCCHC24,NXT2,STX1A,EXOC7,CHST8,TMPO,TRH,PLPPR2,MICAL1,NAV2,ST7" Drug 5724_DN Mefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABHD6,ADCY6,APOC1,ARRB2,C5,KYAT1,SOCS6,CLCN4,ENTPD4,SLITRK5,DZIP3,GIT2,RUSC2,SGSM2,EGFR,IRAK4,STX2,ERAP1,KCNMB4,GNAS,GUCY1B1,MBD1,MX1,ZNF862,NDP,PDE1C,PFKFB2,SAMD9,GON4L,TMEM104,PTCH1,ELOVL2,RAB3A,RGS3,CCDC25,AMBRA1,BTBD7,LIMCH1,TNIK,SS18,COBL,FBXW11,AHCYL2,CABIN1,ZKSCAN5,WNK1,MAP3K12,EVI5" Drug 4296_DN Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADGRF5,KCNAB2,APC,GAS7,MARK4,BCL7A,CAMK2B,MAGI1,WHRN,SLC4A8,TCEAL2,CRMP1,CRY2,ATN1,SUGP2,EN2,PLEKHO1,LRRC23,FLT1,DENND2A,DISC1,C1QL1,POLL,SOX21,ARHGAP19,KCNMA1,NOVA1,PC,ZNF426,TMEM231,RGS10,SLC1A3,SMTN,BTBD7,SMARCA4,TNIK,LHPP,ROBO3,TNS2,SLC44A1,BHLHB9,TNS1,VIPR2,LMF1,CLIP2,LAT2,XRCC4,ZBTB14" Drug 5877_DN Azaperone [1649-18-9]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABHD6,ARID1A,ADD2,EP400,MADD,MARK4,SLC4A4,CFLAR,CDK5R1,C5,ZMYM4,LARGE1,CLU,CSF1,DZIP3,TM9SF4,SIRPA,SGSM2,COQ7,BAIAP2,ZNF276,GLRB,GLS,GPER1,MAPT,SCAMP5,PBX1,PDPK1,PTPA,TMEM104,RAP1GAP,TMEM156,FAM102A,SLC6A8,TMCC1,KDM4C,MAPK8IP3,TTBK2,SYT1,IQCE,WSCD1,TCF4,TNS2,ATP13A2,ZNF34,CADM1,NAV3,ST7" Drug 6582_DN AG-028671 [847803-03-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "APBA2,ALDH4A1,ADGRB2,SYNJ2,WASF1,CDC27,CDH2,B4GALT6,NMT2,CNTN1,VCAN,SOCS5,F3,ACSL4,EFEMP1,ST3GAL6,ZNF589,FYN,GART,USP19,GLRB,CACFD1,MAP4K5,KLF12,ACOT7,KCNMA1,MBNL1,MYO6,CDK18,PDE1C,PLEC,FSD1,PTCH1,FAT4,RGS4,SBF1,ZNF821,SUPT20H,DOCK10,TAB2,KAZN,TNS1,TRIO,CLDND1,ZNF74,FZD3,ST7,UBE3B" Drug 7252_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AMT,CDC42BPA,ST3GAL5,CBFA2T2,SCARB1,CHM,TAOK2,NRXN3,ZFYVE9,QKI,FAM131B,SNPH,DBT,LYPD1,EDIL3,LPAR6,DENND4A,FLT1,CGREF1,TMEM8B,C1QL1,RNFT2,IFI16,SHISAL1,TJAP1,DIPK1A,LIG4,CNOT4,PALM,GON4L,PTPRN2,RGS4,AP1AR,PPP1R9A,SLC1A3,SIRT2,SMARCD3,LIMCH1,KDM4B,SPTAN1,SYT1,ARHGEF12,CHST8,TK2,ZNF45,NT5M,HPS4,PHTF2" Drug 1002_DN 2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AK2,APP,CDK10,MARK4,ATP6V0A1,CFLAR,SYNJ2,GYG2,CCNT1,TAOK2,HOMER3,NCOR1,CTNND2,PARD6A,DLG3,MED12,DTNA,CELSR3,PCOLCE2,ACSL4,SYT17,INPP5K,SRCAP,MAP4,MAPT,NEK1,OGG1,OXTR,PLEC,POLG,TMEM104,SEC61A2,PAQR6,FOXRED2,PEX26,CDK5RAP2,TROVE2,VAMP1,IQCE,SIN3B,KIAA0930,TCF7L2,HEY2,HIRA,EIF4ENIF1,PRDM2,URM1,ST7" Drug 2122_DN Nifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "PKP4,APBB2,CDC14B,MTMR9,BCL2L2,CA12,CANX,RCBTB2,ZNF337,TBC1D5,MATR3,RABGAP1L,SIDT2,COQ7,F3,CGREF1,TRAF3IP2,HBS1L,ZMYND11,GLRB,HTATSF1,GPER1,IFI16,SHISAL1,INPP5B,NACA,SLC11A2,RETREG1,NLE1,PLCD1,MAPK3,MAPK7,TMEM231,ZNF671,SBF1,SUPT20H,SH3BGR,PPP1R9A,ST6GAL1,SYT11,ARHGEF9,EXOC7,FBXW11,ARHGEF12,HIRA,FAM155A,WIPF1,NAV3" Drug 7142_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "SLC4A4,B4GALT6,TPP1,ENTPD4,DCAF8,KIAA0513,KLHL3,EDIL3,SUGP2,C3orf18,FGFR1,ATP2C1,GCNT2,HTATSF1,RNFT2,MEIS1,MPP2,OCRL,OGG1,PIK3R1,LRP12,RIPOR1,TMEM231,RAB3A,NCBP3,ITSN1,RAB3GAP1,SMARCC2,SPATA7,FNBP1,ARHGAP26,ZBTB43,ELOVL4,SEPT8,DIP2A,STX1A,ARHGEF9,TRIM2,ATP13A2,SSBP2,HIRA,LMF1,XRCC4,ZNF45,UPF3A,WIPF2,NUP214,IFT88" Drug 6605_DN Lactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "RALGAPA1,KIDINS220,BIN1,PDE8B,ALDH4A1,SLC4A4,CACNA1A,LARGE1,CHM,TPP1,AKAP7,WHRN,CNIH3,SGSM2,RABGAP1L,TOM1,TNK2,PLEKHO1,COQ7,ERCC2,ZNF549,POLR1B,FGFR1,ANKFY1,DENND2A,GAD1,HLF,HSF2,TJAP1,MDM4,ADAM22,LYRM9,PRKAR1B,GRAMD1C,SAFB,SBF1,ZNF821,ZFP30,BCAN,SLC4A3,TMCC1,MAPK8IP3,CRTC1,CABIN1,RPRM,WIPF1,EMSY,EPM2A" Drug 1181_UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABHD6,MTUS1,BIN1,APBB2,ST3GAL5,SLITRK5,DZIP3,DOCK4,GPRASP1,CDON,TNK2,RRAGB,KIAA1109,FHL1,ANKFY1,PDLIM5,GABRA4,RAB40B,GNAL,GPD2,GPM6B,KCNC1,MAP4,ZNF862,SLC11A2,SERPINE2,STRN3,LRP12,PROX1,SEC61A2,TMEM206,RPS6KA2,WLS,GALNT10,ITSN1,ANKRD6,ADGRL3,ZEB1,DOCK9,TNS2,PARD3,TPD52,SSBP2,FAM155A,REEP1,KCNAB1,PCBP4,FAM13C" Drug 4208_DN Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "PLA2G6,APC,LGR5,MTMR2,LHX2,CLCN3,DNAJB5,RGS6,CHRDL1,ATN1,MBNL2,SORBS3,LRRC23,MTSS1L,FOXG1,SEMA4D,FYB1,ZNF44,SEPT9,AHDC1,GPD2,GRIK2,GRM8,SOX21,KIF5C,KPNA5,PACRG,RETREG1,PROX1,PTPRB,RAB3A,RAD52,RGS4,ATXN7,FRMPD1,SLC1A7,PPP4R3A,KANSL3,MYH15,SPATA7,VAMP1,TRIM2,CABIN1,TRIO,RUNDC3B,VIPR2,ZNF711,EVI5" Drug 3055_UP Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACTN2,MTUS1,LTBP4,ALK,CDK10,DDX3Y,CCDC181,ATP2B3,RGS9,BMP7,FUBP1,CACNA2D1,USP2,AKAP6,COL9A3,ARHGEF10,PPP1R16B,USP6NL,DNAJC6,APC2,KAT8,BAIAP2,PRELID3A,RUNDC3A,PCLO,GUCY1A1,KCND3,NCAM1,NPY,PDE1C,BCAS3,PTHLH,PTPN13,BEND5,MYH14,CLIP1,RYR1,SCN8A,ASAP3,SPTB,NFASC,TACR1,ATP13A2,TK2,VAV2,KLC2,MAP3K12,GDPD5" Drug 7139_DN "Chrysene-1,4-quinone [100900-16-1]; Down 200; 15.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "GRAMD1B,CAPRIN2,ATM,BCL2L2,ARHGEF7,MTMR3,WASF1,CAMK2G,RNF14,NCOR1,ARHGEF10,SOCS5,TBC1D5,GIT2,RBM12,LPAR6,EML1,SCML2,ZNF589,POLR1B,CAMSAP1,CAMKK2,GBX2,PRRC2B,EML4,NR3C1,IFI16,ITPKB,NACA,NFYA,NOVA1,SLC11A2,PDGFRA,RALGDS,KIF16B,NUBPL,WDR37,FNBP1,CLASP2,ZC3H4,TACC1,DNMBP,TCF7L2,PSD3,NSD1,NACC2,METTL3,SF1" Drug 3453_DN Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "EPB41L5,APP,BCL2L2,BMP7,ST3GAL5,BTRC,RAB28,QKI,COL9A2,BAG4,CTNND2,SGSM2,DTNA,SUGP2,MBNL2,LRRC23,EZH1,F3,SCML2,BAIAP2,FAM49B,INPP5K,ARFIP1,MALT1,EML4,NR3C1,HNMT,MAPT,ADAM22,RIPOR1,CEP97,GTDC1,SFPQ,KBTBD4,ZHX3,TSPYL2,LHPP,CLASP2,SS18,SEMA4A,MCF2L,TCF7,TMPO,PARD3,TRPC1,VAV2,XRCC4,GDPD5" Drug 7224_DN Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ASPHD1,KIDINS220,DGKD,PPFIA3,NCOA1,ATP2B1,SYNJ2,C5,QKI,SLC4A7,CREM,ABCG1,MICAL2,DZIP3,DCTN1,FBXL5,SMG7,SGSM2,DMPK,EDNRA,EGFR,MBNL2,BAIAP2,DPYSL4,ZNF276,HNMT,INPP5B,IPO5,MAP4,OGG1,PDE4A,SMIM7,PPP2R5C,RIPOR1,NKAIN1,FBXW7,SBF1,KIF16B,MAPKBP1,TMCC1,TROVE2,CAMTA2,FAM168A,VPS13A,TCF7L2,VAV1,REEP1,SCG2" Drug 3482_DN Pyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG2,ADRA1D,BIN1,APC,PPFIA3,ARNTL,CDK13,STX16,ST3GAL5,SCAPER,C5,CFAP410,SOCS6,PLEKHB1,LHX2,ABI3BP,EDRF1,DBN1,MFAP3L,SLC12A6,ATN1,HIPK3,EFNB3,EIF4G2,LRRC23,F3,FGFR1,ZNF276,LPAR4,HNMT,ICA1,INPP5B,RETREG1,MBOAT7,MINDY2,PPP5C,MAPK10,GON4L,RGS10,NEK11,ZNF821,SLC22A4,LIMCH1,TSNAXIP1,ATP11A,TMOD1,RBFOX2,MPPE1" Drug 6372_UP 3-nitropropionic acid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "PKP4,GAS7,BCAS1,APP,SLC4A4,SLC2A11,CDK5R1,BAIAP3,STOML1,SULT4A1,SLITRK5,TOX,LYPD1,DTNB,EN2,PDLIM5,FYB1,DISC1,GFER,GNG3,LILRA2,GRIN1,KCNMA1,TAGLN3,ZNF862,DUSP26,PLCB2,LRRN3,PRKAR1B,SAMD9,PLPPR1,ACSS3,RNASE1,SALL1,ZNF821,SLC15A2,SMARCD3,ZNF415,KDM4B,DDN,TROVE2,SYT1,TNS1,TPM1,VGF,VIPR2,XRCC4,PARP6" Drug 3288_DN Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ASPHD1,APOC1,ASPH,ALDH4A1,SYNJ2,CFAP410,ARHGEF2,CACNA2D2,LHX2,EPS15L1,ZFYVE9,QKI,CSNK1E,DCTN1,RCAN1,TOM1,CELSR3,PLEKHO1,STX2,F8,BAIAP2,FAM49B,CGREF1,GPD2,GSN,BRINP3,MAP4,KITLG,GIT1,NUMA1,PDE4A,SLC25A23,PLXNB1,MBOAT7,MAPK7,MSANTD2,GSTCD,ZFP30,PDZRN3,WDTC1,CEP68,VPS13A,SEMA4A,EXOC7,KIAA0930,TCF7,MARCH8,RNF170" Drug 2339_UP Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "MTUS1,MRTFA,MARK4,CAPRIN2,BMP7,CDK5R1,GPR37L1,SULT4A1,SLC4A7,CREM,CSF1,VCAN,SLITRK5,PPP1R16B,RCAN1,DLC1,TESK2,PDLIM5,GABRA4,INPP5K,LSS,AFF1,NF1,NUMA1,P2RY1,PFKFB3,PLP1,SLC25A23,FAM184A,PLPPR3,FNDC3A,SHANK2,SNCA,TMCC1,KDM4B,ZBTB43,ATP10B,CLSTN2,STXBP1,KAZN,DNMBP,TBL1X,SIN3B,TCF7L2,CRTC1,TK2,CDK20,UBE3B" Drug 4166_DN Solanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ASPHD1,NRP2,ARHGEF7,CFAP410,CA4,ARHGEF1,CBFA2T2,ARHGEF2,FOXN3,SNCAIP,PDE4DIP,PHF14,SORBS3,SCML2,ZNF589,DPYSL4,KHDRBS3,SEPT9,RND1,GLYR1,POLL,GPER1,GSN,RNFT2,BRINP3,KCNK2,KCNN1,AFF1,ADAM22,MX1,NEUROD1,SERPINI1,PLEC,RGS10,KCNIP1,DHX30,COA1,SNAP25,ZHX3,THSD1,PLCB1,TCF7,HEY2,PARD3,TRPM2,MICAL1,REEP1,PDSS2" Drug 1604_UP Clorgyline hydrochloride [17780-75-5]; Up 200; 13uM; HL60; HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AP1B1,MARK4,ATM,EIF4G3,ATP2B1,RAB28,CLCN3,PPP1R16B,PPP6R2,RUBCN,ARHGAP32,DCAF8,GIT2,FEM1B,CELSR3,OLIG2,ENO2,STX2,SEC23B,SMC2,ATP2C1,OGA,NR3C1,IFI16,LAMP2,PLCD1,PLEC,MAPK3,SAMD9,PTX3,RPS6KA2,ATXN7,DOCK10,ELMO2,KDM4B,WDTC1,GLT8D1,CDK19,THSD1,MAPK8IP3,KLHL7,RBFOX2,NR2C2,HIRA,WIPF1,HPS4,RNF170,AAAS" Drug 6844_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "EPB41L5,NCOA1,BTRC,CNOT8,NMT2,QKI,AKAP12,NCOR1,CTNND2,RIMS2,EXOG,DMTN,ZNF589,FGF12,FGFR3,MALT1,GNG4,GPR19,IGSF1,JAK2,KCNH2,KCNJ3,MAPT,TM6SF1,MEIS2,NFYA,PCDH9,PDE3B,PRKAR1B,RGS12,PAQR6,WLS,SHANK2,SNCA,SPTAN1,SEPT8,TTBK2,ANKRD28,IQCE,CRTC1,TMEM121,SLC44A1,TK2,ZKSCAN5,ZBTB14,ZNF45,TFIP11,SSPN" Drug 5000_UP "Amethopterin (R,S) [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADRA1D,LTBP4,APLP1,ADAM23,CAMK2B,CRLF1,ASIC3,SULT4A1,NRG2,SH2B1,DRD1,ELN,VPS13B,EPHB1,DLC1,FGFR3,CAMSAP1,SCARA3,SORBS1,GAD1,SIGLEC8,SRCAP,SESN1,RND1,GNAO1,GPD1,GRM1,ICA1,KCNH2,KIF5C,MIA2,ADAM22,NF1,NOS1,PFKFB4,MBOAT7,MAPK8,RPS6KA2,FRMPD1,ATP10B,ATP11A,SEMA4A,WSCD1,ZEB1,PCDHA5,TNS1,METTL3,KCNK12" Drug 3397_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ASIC1,NDRG2,LTBP4,BIN1,APC,BCAS1,ALDH7A1,GYG2,FADS2,RCHY1,CSF1,KIAA0586,ATN1,DSCAM,ELN,SPEG,ZNF589,FGF12,CAMSAP1,GAD2,TMEM8B,RND1,TDRKH,ITPKB,JAK2,SMAD1,MSI1,NEK1,SETD4,PALM,PDE3B,CDK14,RETREG1,RGS3,SUPT20H,ITSN1,ASAP3,PKNOX2,SMARCD3,SNCA,KIF13A,ZCCHC24,THSD1,SEMA4A,PDIA2,MICAL1,WIPF1,DNALI1" Drug 3372_UP Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG2,ADCY2,KIAA1324,ATP2A2,BAIAP3,LDLRAD4,CFAP410,CDH8,PLEKHB1,SULT4A1,COL9A3,NRG2,NCOR2,AATK,MICAL2,DGKG,BRINP1,RUSC2,SPOCK3,HS3ST2,USH1C,SGK2,EGFR,TNK2,ERCC2,CEND1,PTK2B,FHL1,GLYR1,GPM6B,GRIK5,KLF12,KIF5A,LMO2,KITLG,MOBP,BCO1,ZNF862,NPPA,RFX2,SH3GL3,SLA,RPH3A,DICER1,GPR161,TRPM2,FLRT2,KCNAB1" Drug 7092_UP GSK-3beta Inhibitor VIII; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ASIC1,MTUS1,LTBP4,MRTFA,CDK10,MARK4,BMP7,SYNJ2,ENTPD6,WHRN,CRY2,CSNK1E,PDE4DIP,NOS1AP,GIT2,RABGAP1L,SUGP2,MRNIP,ERCC2,F3,SEMA4D,OGA,SRCAP,DIDO1,ADAMTS13,NR3C1,ATXN2L,IL6R,IL6ST,KCNH2,KCNJ3,MAN2A2,MAP4,LYRM9,CDK18,PIK3R1,CNNM2,RNASEL,RXRA,ZNF821,ZHX3,ZBTB43,POGZ,SS18,VPS13A,TRPC1,VLDLR,LMF1" Drug 4752_DN Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AK2,LTBP4,BIN1,GAS7,MARK4,GYG2,CBFA2T2,ARHGAP33,CLGN,FOXN3,COL4A5,CTH,EFNB3,STX2,NCALD,ZNF589,KIAA1109,C1orf61,IQCG,HBS1L,INPP5K,SRCAP,ZNF276,GLYR1,GLS,GRM1,MEF2C,KITLG,MID1,ADAM22,MYT1,PPP5C,RAB3A,RAD52,ROM1,FBXW7,FBXO11,SMARCD3,KIF13A,ZCCHC24,SPTAN1,DMXL2,CRTC1,PCDHA5,TMEM121,CABIN1,REEP1,SSPN" Drug 1964_DN Cimetidine [51481-61-9]; Down 200; 15.8uM; HL60; HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACTN1,NDRG2,ADAM23,SYNJ1,RUNX1T1,KRIT1,LRBA,FOXN3,TBC1D5,MAML1,GIT2,RCAN1,SUGP2,DENND4A,SEC23B,FAM49B,STAG2,ARFIP1,GLUL,LILRA2,GRB10,KTN1,MAP4,MITF,OCRL,OPA1,LGR4,CLIP1,ATXN2,SH3BP2,DOCK10,PEX26,CCDC88A,SCMH1,GLT8D1,ARHGAP26,RBM26,DIP2A,TACC1,TMPO,TPD52,CHST5,UBTF,GORASP1,LAT2,CLDND1,ZNF142,URM1" Drug 1010_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABR,ABHD6,AK2,ATP6V0A1,CFLAR,B4GALT6,LHX2,EPS15L1,DBT,FCF1,OLFM1,CINP,GHR,FERMT2,MUM1,BRINP3,KCNJ3,KHK,MMP16,GIT1,NAP1L2,NASP,NEK1,NFYA,SLC11A2,NRGN,OGG1,PLXNB1,LRP12,LRRC49,ZCWPW1,FAM192A,FOXRED2,ZFP30,EPN2,CLASP2,NXT2,SYT1,SEMA4A,HEY2,RBFOX2,PLPPR2,ZBTB14,ZNF45,NDRG4,CIAPIN1,PHTF2,SSPN" Drug 7314_UP Nifenazone [2139-47-1]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG2,FAM135A,MRTFA,KCNAB2,EPB41L5,APOC1,MARK4,ALDH7A1,BAIAP3,BTRC,MAP7,SCARB1,STOML1,ENTPD4,ARHGEF10,RUSC2,SPOCK3,IRAK4,ABCA8,ZNF589,BAIAP2,TRMO,INPP5K,SPACA9,ATXN2L,ELOVL5,MATN3,SCAMP5,MYH3,NDP,NF1,CAMKV,CCSER2,CNNM2,FAM184A,RGS4,ARHGEF10L,PAQR6,RXRA,ASAP3,THSD1,MAPK8IP3,SYT1,EXOC7,THRA,VAV2,WIPF1,ZNF74" Drug 2103_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADD1,APC,APP,CDC14B,CANX,MAP7,FOXN3,KIAA1549L,HOMER3,PARD6A,EFNA3,SUGP2,EPB41L1,COQ7,SPEG,ZNF589,FGF1,FGFR1,SRCAP,GPD2,CLASRP,SHISAL1,INPP5B,JAK2,MAP4,MPP2,ZNF862,ODF2,LRP12,SAMD9,GON4L,RIPOR1,FAM184A,ZDHHC14,RGS4,SLC20A2,CAMTA2,SS18,ATP11A,EXOC7,PDLIM2,ZEB1,SZT2,CABIN1,TPD52,ZNF45,ZNF189,PRDM2" Drug 5447_DN Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABR,ASIC1,LTBP4,PPFIA3,TPP1,FAM169A,SDC3,KIAA0586,GIT2,DSCAM,EIF4G2,SORBS3,PLEKHO1,DMTN,FHL1,MPP6,DISC1,MALT1,PRRC2B,GPM6B,TDRKH,SLC2A6,IL6ST,INPP5B,JAK2,KPNA5,LMO2,TM6SF1,NDUFA5,NUMA1,PC,PTHLH,CEP97,EMID1,SOX3,EMC1,SPART,INKA2,MAPK8IP3,PLCB1,MTCL1,MCF2L,TGFBR3,VGF,KLC2,SPHK2,MAP3K12,MVB12B" Drug 4149_UP Dibucaine [85-79-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "RALGAPA1,AP2A2,AGT,MARK4,ATP2B2,CFLAR,SYNJ2,CACNA1I,RUNX1T1,USP2,ADGRG1,CHGA,AKAP7,DAPK1,CTIF,DRP2,DYRK1A,SNX29,CALCRL,ETV1,AGAP2,FAM49B,OGA,GRIK2,HRH3,KLF12,KCNB1,KCNJ10,LIFR,NPR2,PLP1,STRN3,PPP5C,SAMD9,GDPD2,RYR3,DOCK10,ST6GAL1,PKNOX2,SLCO1A2,RBM26,MAPK8IP3,CRB1,WIPF1,SLC30A3,SLC17A7,PHTF2,NLRP3" Drug 4840_DN Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "BRAP,PKP4,APBB2,PPFIA3,CDC14B,CDK10,ATP6V0A1,CFLAR,RAB29,MAP7,KRIT1,SCARB1,PLEKHB1,NIPBL,AKAP7,WHRN,COL4A5,RIMS3,FCF1,SIDT2,SORBS3,IRAK4,ENO2,PRKAG2,DISC1,MALT1,CRCP,DHX35,KCNF1,MAP4,MBD1,RETREG1,SLC25A23,PEX5,RAD51D,RAD52,SLC6A8,SPATA7,SS18,FCHO1,CAMSAP2,SLC44A1,RUNDC3B,SPHK2,REEP1,EVI5,URM1,UBE3B" Drug 7055_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AP2A2,SEMA6A,LTBP4,DOC2A,APBB2,ARHGDIG,BCL7A,BMP7,SGCE,CA12,FOXN3,USP6NL,LYPD1,ATN1,SORBS3,HSD17B14,BAIAP2,DPYSL4,FAM49B,DISC1,GPD2,STON1,GPER1,CACFD1,ATXN2L,VWA5A,MAP4,MITF,MMP16,CLDN11,PCDH9,MINDY2,CEP97,RGS3,TCP11L1,EMID1,MAPK12,SH3BP2,MAPKBP1,DOP1A,KDM4C,ARHGAP26,IQSEC2,PHLDB1,TMPO,TSC2,VIPR2,VSNL1" Drug 6315_DN Prazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG3,CDC42BPA,ARRB2,KSR1,NFS1,CREM,ARHGEF4,PPP6R2,SMG7,DLG3,DTNA,EGFR,ANKMY1,TUBB4A,TACC2,CGREF1,DLL3,ERAP1,TXNL4A,GLYR1,BTN2A1,SYNPO,KCNMA1,MAPT,MYO6,NUCB1,PTPA,MAPK7,PEX5,PID1,GAL3ST4,RPS6KA2,SBF1,FAM102A,IFT122,TMCC1,WDTC1,TSPYL2,SAMSN1,ELOVL4,ARHGEF9,BHLHB9,TSC2,PLPPR2,MICAL1,ZNF45,MAP3K12,PCBP4" Drug 6708_DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "RALGAPA1,TRMT9B,ANK3,PDE8B,SLC4A4,STX16,FOXN3,CHM,KIAA1549L,QKI,CNTNAP2,RCAN1,FCF1,COQ7,ETV1,CINP,OGA,GPD2,GPM6B,INPP5B,KPNA5,NASP,NDP,NEK1,NFYA,NUMA1,CLDN11,PDE4D,PLXNB1,TMEM231,RAD52,ATG16L1,RPS6KA2,ASAP3,PPP4R3A,SPTAN1,POGZ,NCDN,TCF4,TCF7L2,DNAH7,GPR161,THRA,TMPO,RUNDC3B,HIRA,EPM2A,PHTF2" Drug 6084_UP Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NLGN4X,LTBP4,ALK,BIN1,ARHGDIG,PLA2G4C,ATP2B2,CFAP410,ARHGEF2,SULT4A1,LY86,CNN3,CSF1,ARHGEF10,MICAL2,CHD5,VCAN,RASSF2,BRINP1,DCC,LRRC23,SPEG,REEP2,FHL1,FYB1,RUNDC3A,GRK4,GRIN2C,GSN,KHK,KCNK10,SNTG1,SAMD9,PTPRB,FAM120C,KCNIP2,ZFP2,SH3BP2,SLC6A9,ARHGEF40,SSTR2,ZEB1,FAM189A1,TMOD1,SLC30A3,STMN4,PLSCR4,KAT6A" Drug 6808_UP Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACTN1,ADORA1,AGT,AMH,AMPD3,BIN1,OGT,EP400,BCL2L2,CALB1,ARHGAP33,CPS1,GREB1,DTNA,EGR3,DENND4A,ACSL4,GNAS,KCNMA1,KCNQ3,CLDN11,SMOX,C19orf57,MAPK10,PTHLH,FAM120C,RET,GTDC1,SBF1,FBXO11,SLN,SMARCD3,KDM4B,WDTC1,ZCCHC24,AJAP1,FAM168A,KAZN,HEY2,R3HDM1,TPM2,FAM155A,LMF1,SPHK2,SLC17A7,KAT6A,SMIM8,SENP7" Drug 7430_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AP2A2,ALCAM,APOC1,BCAS1,CDK10,ATM,ADGRG1,QKI,AKAP7,PDE4DIP,RUBCN,EDRF1,GPRASP1,DCAF8,KIAA0586,PARD6A,DTNA,EML1,PLEKHO1,FYN,MSL3,KIF5C,PDE3B,NLE1,SLC25A23,FA2H,PRKAR1B,PTPN13,TMEM231,GTDC1,FERMT1,ANKRD6,PEX26,SLC6A8,WDTC1,UHRF1BP1L,LHPP,POGZ,COBL,ANKRD12,MCF2L,PDLIM2,PCDHA6,CABIN1,MPPE1,ST7,KAT6A,GAN" Drug 5277_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "DPF1,AQP6,MARK4,CACNA1I,RUNX1T1,TPP1,FAM189A2,CNTN1,SNPH,C2CD2L,ST8SIA3,EDN3,TNK2,RASGRP2,IGSF6,PTK2B,KIAA1109,OLFM1,FHL1,FOXG1,FAM49B,FYN,DISC1,RUNDC3A,GRM1,IL6R,IL12A,ITIH2,CD200,MSR1,NCF2,CLDN11,TREM2,PCDH9,SERPINE2,EPN1,SBF1,SLC14A1,SPTB,IQSEC2,TCF7L2,PCDHGB6,CHST5,UBE3A,VGF,MICAL1,LAT2,EVI5" Drug 5754_DN Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AP2A2,NME5,PPFIA3,SEMA4G,MARCH3,SLC4A4,CFLAR,KYAT1,CLCN4,DNAJB5,SULT4A1,CREB5,USP6NL,GIT2,CDON,DPH1,FAM13A,EIF4G2,DENND4A,FGF1,FGFR1,IQCG,CINP,FYN,GLI2,MUM1,LIFR,ADAM22,TAGLN3,NEK1,NF1,POLG,MAPK7,RIPOR1,SH3TC2,RPS6KA2,CLIP1,IFT122,SNCA,CAMTA2,COLGALT2,MAPK8IP3,EXOC7,TK2,CABIN1,TNS1,LMF1,PHTF2" Drug 4697_DN Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AK2,BIN1,CDC42BPA,APBA2,APC,MARK4,ATM,BTRC,CA12,ARHGEF2,SLIT2,QKI,AKAP7,SH2B1,ARHGEF4,SMG7,SGSM2,RABGAP1L,TRAPPC9,DSCAM,DTNA,EDNRA,SEPT9,TDRKH,GRM8,KIF2A,MAP4,MIA2,NCAM2,NEUROD1,NF1,SMIM7,PPARA,RGS10,ZNF821,BTBD7,SOX2,ZCCHC24,ZHX3,ARHGAP26,MAPK8IP3,ARC,TNS2,PARD3,TRIO,VIPR2,EVI5,TIGD6" Drug 5739_DN Cytisine (-) [485-35-8]; Down 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "CDC14B,BCL2L2,CFLAR,CBFA2T2,SOCS6,ENTPD4,SLITRK5,EDRF1,PARD6A,EIF4G2,TENM1,ANKMY1,SCML2,FGFR1,PDLIM5,FAM49B,B4GALNT1,ZNF276,GPR37,RASSF8,KIF2A,MAP4,MAPT,MIA2,CDIP1,MAPK7,ELOVL2,PEX5,RAB3IL1,FAM184A,GAL3ST4,SUGCT,MAPK12,IL17RB,AMBRA1,SIRT2,SLC20A2,IFT122,KDM4C,ARHGAP26,SUPT5H,SYT1,IQCE,CHST8,GPR161,LMF1,TFIP11,EVI5" Drug 6899_DN SB 203580; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADORA2A,CDC42BPA,BTRC,MAGI1,CLGN,SOCS6,RAB28,TPP1,QKI,IQCK,CREM,TBC1D5,CNNM1,OLIG2,DMTN,VPS26C,ZNF589,TRAF3IP2,USP19,C1QL1,GLYR1,GLS,BTN2A1,INPP1,PDE3B,PLCD1,MAPK7,PTAFR,C1orf54,ZDHHC14,SH3BP2,FRMPD1,SLC1A7,PREX2,LIMCH1,UNC5B,ARHGAP26,IQSEC2,ATP11A,TCF7,TRIM2,PSD3,BEX4,TUBB1,MICAL1,LAT2,HPS4,TIGD6" Drug 896_DN 5152487; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "LTBP4,ANK3,STX16,REPS2,TAOK2,QKI,ENTPD4,RUBCN,RABGAP1L,EFNB3,EML1,DMTN,FHL1,POMT1,PDLIM5,CRCP,KCNMB4,AGFG1,KCNK1,IPO5,MAP4,MAPT,NF1,SLC11A2,RETREG1,PPP2R5C,MAPK8,RALGDS,CCDC25,ZNF821,SLC6A8,SLC15A2,ZBTB43,ELOVL4,TACC1,EXOC7,FBXW11,AHCYL2,ATP13A2,CABIN1,TPM1,TRPC1,ZMYND8,HIRA,SF1,GDPD5,PCBP4,EPM2A" Drug 1930_UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "APP,AQP6,MAP7,IFFO1,PDE4DIP,ECE2,SPATA2,KLHL3,EDN1,ING4,EML1,EZH1,GFER,GLS,DIDO1,SHISAL1,KCNJ3,KIF5A,GIT1,MYL3,NELL2,NFYA,CDK18,PPP2R2B,CEP41,MAPK7,PTN,RAB3A,RET,MAPK12,ATXN2,SH3BP2,ARHGEF40,ZKSCAN3,ZBTB43,WSCD1,TNS2,PLPPR2,VIPR2,LAT2,WRN,ZBTB14,ZNF24,REEP1,GDPD5,MVB12B,AAAS,DPF3" Drug 1959_DN Paclitaxel [33069-62-4]; Down 200; 4.6uM; PC3; HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "MAP4K3,GAS7,APP,ASPH,ATP2B1,WASF1,CDC27,COL4A5,SLC4A7,SOCS5,APPL1,SPOCK2,ZBTB24,FBXL5,G3BP2,SH3YL1,SEC23B,PDLIM5,FAM49B,ATP2C1,STAG2,NCKAP1,GLS,IL6ST,KTN1,NAP1L1,NAP1L2,SLC11A2,NUCB2,PCMT1,PIK3C2A,PPM1B,C1orf109,RBBP6,RGS10,LGR4,PEG10,ZNF302,LARP4,SEPT8,CEP68,KLHL7,TCF7L2,TRPS1,UBE3A,ZNF189,EVI5,PHTF2" Drug 6863_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACTN2,KIAA1324,CDK10,SEMA4G,RGS11,NRP2,SCAPER,BTRC,ARHGAP33,NRXN3,AKAP7,ARMC8,ACOT8,ATN1,ST8SIA3,FEM1B,FCF1,MBNL2,EIF5,SEMA4D,DCTN2,GAB1,HBS1L,SYT17,GNG3,TDRKH,GRM7,KLF12,SHISAL1,KCNJ4,MBD1,NOVA2,NPR2,ELOVL2,FAM120C,TMEM231,RAD52,RGS12,TTLL7,NEK11,ATXN2,THSD1,NCDN,JMJD6,MCF2L,CDK20,ZMYND8,ZNF45" Drug 6666_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AMPD3,ALDH4A1,KIF1A,ADAM23,ARHGEF1,CBFA2T2,SYNGR3,NRXN3,STOML1,QKI,VCAN,PDE4DIP,ARHGEF4,RIMS2,RUSC2,SPOCK3,EFNA3,PLXNC1,AASS,TENM1,LRRC23,MTSS1L,BAIAP2,DCTN2,CINP,GNAL,GNG4,GRM8,NOVA2,NLE1,PPP5C,SAMD9,PID1,RAD52,RALGDS,ZCWPW1,ITSN1,DZIP1,ZNF667,WDTC1,IQSEC2,SAMSN1,KAZN,WWC1,TBCEL,GPR161,TIAM1,SEMA3B" Drug 4812_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "OSBPL1A,AK2,ATP6V0A1,SCARB1,FADS2,NIPBL,USP6NL,G3BP2,TSPAN5,FEM1B,SIDT2,DCTN4,DENND4A,ANKMY1,MALT1,GPR37,ELOVL5,DHX35,IPO5,NF1,PDE3B,CCSER2,SLC25A23,STRN3,PTK2,RAB3IL1,CEP97,RAD52,SEC14L1,ELMO2,BTBD7,LIMCH1,RBM34,KDM3A,TROVE2,SS18,PHLDB1,SYT1,TACC1,TCF7L2,TMOD1,RUNDC3B,LMF1,ZNF32,EVI5,MPPE1,PHTF2,RNF146" Drug 411_UP sodium 4-phenylbutyrate; Up 200; 1000uM; HL60; HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "NDRG2,CAPRIN2,ZSCAN18,MTMR3,CBR1,CD38,CLCN3,STOML1,DGKG,GIT2,C2CD2L,EFNB3,EGFR,ING4,BAIAP2,POMT1,PDLIM5,FYN,LYVE1,GRIK5,IFI16,KIF5C,ADAM22,NINJ2,NRGN,PDE4B,PLCD1,MED1,RIPOR1,RAB3A,PAQR6,ZNF821,ZFP30,ITSN1,DOCK10,CHD9,KIF1B,SRPK2,POGZ,TCF4,ZEB1,SEZ6L,KLC2,ZNF142,LMAN2L,MPPE1,PDSS2,ZNF248" Drug 2775_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ADCY6,CDC42BPA,APP,GYG2,CAMK2G,CNOT8,SLIT2,CLCN3,CRY2,PDE4DIP,PARD6A,DTNA,SIDT2,EFNB3,FGFR1,ANKFY1,GPR153,ALDH1L1,TXNL4A,MSL3,GPD2,BTN2A1,ITPKB,MAN2A2,ZNF862,CNOT4,STRN3,MAPK7,SBF1,ASAP3,SLC1A7,SLC6A8,LIMCH1,MAPKBP1,WDTC1,ZCCHC24,CDK19,ST5,STX1A,ASTN2,ANKRD12,RPGRIP1L,WDR7,PCDHA6,AHCYL2,PARD3,VLDLR,REEP1" Drug 5519_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ABHD6,SLC12A5,MTUS1,APC,CASK,ATM,CFLAR,ST3GAL5,SCAPER,SRSF11,NECTIN3,PDE4DIP,GIT2,MAMLD1,MRNIP,COQ7,VPS26C,ANKMY1,FECH,SEMA4D,DPYSL4,TRMO,HBS1L,CIT,KIF2A,VWA5A,ADAM22,KLK6,ZCWPW1,RGS12,SBF1,AMBRA1,FBXO11,SCMH1,SLC22A4,MCF2L,EXOC7,FBXW11,TIAM1,TPD52,TPM1,TRIO,TSC2,TFIP11,VPS35L,MPPE1,KAT6A,SSPN" Drug 4591_DN Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "C1QTNF1,MRTFA,ADGRB2,CACNB2,CCNT1,DNAJB5,AATK,ARHGEF10,DBT,ARMCX2,EDNRA,CNNM1,ELAVL3,LRRC23,FGFR1,PRELID3A,CGREF1,FYB1,ZNF276,MEF2C,GIT1,LYRM9,ZNF862,NDP,ODF2,NLE1,PPP5C,MYH14,ROM1,ZNF671,TCP11L1,RPS6KA2,IL17RB,ZNF821,ITSN1,BCAN,SLC4A3,ZNF334,SLC22A4,CEP68,VAMP1,ASTN2,KAZN,TCF4,AHCYL2,VGF,VIPR2,UBE3B" Drug 6845_UP Ampyrone [83-07-8]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "AP2A2,PLA2G6,ALAD,MRTFA,KCNAB2,SLC4A4,CFLAR,ADGRG1,CHN2,TAOK2,DNAJB5,SULT4A1,RIMS3,EFNB3,MBNL2,ERCC2,DLC1,KAT8,PCLO,GRM1,ICA1,TJAP1,MAP2,MMP16,ADAM22,MYT1,NF1,NNAT,NTRK2,NUMA1,RIPOR1,RAD52,ZFHX4,MYH14,RYR1,SBF1,ZNF821,FAM214B,SNCA,KDM4B,WDTC1,ZCCHC24,SYN2,WSCD1,DICER1,GPR161,UCHL1,AP3B2" Drug 1301_DN Domperidone maleate; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "RBM10,BRAP,PLA2G6,AMPD3,ARHGEF1,NCOR1,CSF1,BSCL2,ERCC2,FGFR1,SEPT9,GLYR1,PRRC2B,LILRA2,STON1,FICD,VWA5A,MAP4,ZNF862,OGDH,PDE4A,RETREG1,PLEC,RAD52,DPF2,RGS10,FBXW7,ATXN7,SLC11A1,KBTBD4,SMARCC2,MAPKBP1,ZCCHC24,FCHO1,MLC1,PRRC2C,PDLIM2,TCF7,SYNE1,PARD3,KAT6B,TNNT1,TNS1,RBFOX2,WBP2,UBTF,NPDC1,PRDM2" Drug 4390_UP Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "C1QTNF1,GAS7,N4BP2L1,BAIAP3,CAMK2B,BRSK2,RUNX1T1,GPR37L1,FHL5,AKAP5,CSF1,ATRNL1,VCAN,SLITRK5,CYBB,SV2A,ATN1,USH1C,TENM1,TNK2,ELN,RCAN2,LRRC17,EPHA5,GABRA2,LILRB4,PRUNE2,GPER1,GRIN2C,MEF2C,DDX25,MYBPC1,PDE1C,PACSIN1,LRRN3,VPS13C,PTAFR,CCDC40,RASGRF1,SCN2B,SLC1A7,SHANK2,FAIM2,ZC3H13,SYT5,PCDHGB6,OSBP2,SLC30A3" Drug 2621_DN Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "APP,ARNTL,ALDH4A1,STX16,CFLAR,BMP7,GYG2,CAMK2B,SOCS6,QKI,SIPA1L1,PDE4DIP,EDRF1,FCF1,EFNA3,SUGP2,EGFR,FER,AGAP2,NOP56,GPER1,GRIK5,RNFT2,HNMT,KIF5C,IPO5,MAPT,NCAM2,OGG1,WDR25,ELOVL2,PEX5,CEP97,ZDHHC14,EMID1,FOXRED2,ZNF821,SMTN,SNCA,SOX3,NXT2,ATP11A,TMPO,CABIN1,CDK20,XRCC4,REEP1,RNF146" Drug 4141_UP Metronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACTN2,LTBP4,MRTFA,APAF1,APBA2,RASL11B,ATP1A3,ATP2B2,RUNX1T1,NEURL1,CDH10,CHN2,CLCN4,CSF1,RIMS2,BRINP1,ELMO1,KLHL3,ATN1,EFNB3,PLXNC1,KIAA1109,GAD1,ATXN2L,ACOT7,ICA1,KCNMA1,MDM4,MID1,ADAM22,CLDN11,ENPP2,PRKCB,FOXRED2,SH3BP2,SLC1A2,SLC2A5,ATP10B,KIAA1107,WSCD1,OBSL1,HIF3A,PIK3R5,TRPC3,VAV2,WIPF1,SLC17A7,MARCH8" Drug 631_DN benserazide hydrochloride; Down 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Down 9.22E-04 1.00E+00 6.58E-03 7.49E-02 48 196 "ACLY,PLA2G6,BCAR3,ARRB2,ADAM15,AZGP1,NRP2,CACNA1I,MAP7,CBFA2T2,CDC27,ARHGAP33,NIPBL,CRMP1,DAPK3,DNAJB6,FAM13A,ABI2,DCTN4,FGFR1,B3GAT1,SPIN1,DIDO1,BTN2A1,CELF3,STMN1,MAP4,NF1,POLG,FSD1,PPP3CA,MAPK7,GON4L,RBBP6,MSANTD2,KDM4C,TEX2,MAPK8IP3,PHLDB1,FRYL,CHST5,ZNF384,TRIO,TSN,UBE3A,UBTF,KLC2,SNX27" Drug CID000004782 eye gene Stitch 9.24E-04 1.00E+00 6.59E-03 7.50E-02 81 369 "ADCY2,ADCY5,ADCY6,ADCY8,ADD1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,MYH7B,DGKZ,IGDCC4,ALDH7A1,CACNA1D,CACNA2D1,CACNB2,CHRM1,MYL6B,PLCXD3,MYEF2,DRD1,EDN1,EDN3,EDNRA,EDNRB,ACTL6B,LOXL3,PLCD4,GUCY1A2,GUCY1B1,MYLK2,IGF1,RBPJ,KCNC1,KCND2,KCND3,KCNN1,KCNN3,MAOB,AFDN,BCO1,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NOS1,NPY,NPPA,NPR2,PDE3A,PDE3B,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,PYGM,MYH14,MAPK12,MYO18A,SLC12A2,PEG10,MLC1,PLCB1,TAC1,ACTR6,TRPC1,TSC2,TTPA,UBTF,PLD4" Drug 3448_UP Dienestrol [84-17-3]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "NME5,AK2,MRTFA,CDC42BPA,CDK13,MARK4,RASL11B,ALDH4A1,MTMR3,CACNB4,CACNA2D2,VAX2,CTIF,CNNM1,EGFR,EGR3,LRRC17,DLC1,FGF12,BAIAP2,FOXG1,DISC1,RND1,NXPH3,TJAP1,TM6SF1,MITF,NNAT,SMOX,ELOVL2,ZDHHC14,ZFHX4,SUPT20H,RASA3,SGK1,SYBU,PREX2,EPN2,BTBD7,OGDHL,KDM4B,ARHGAP26,SPTAN1,ARC,PCDHA5,LAT2,SEMA3B" Drug 3823_DN CP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "ACTN1,ADRA1D,MRTFA,SEMA7A,IL33,BTRC,CBS,ARHGAP33,CLCN4,AKAP7,RCHY1,HAPLN1,TENM4,VCAN,TOX,LYPD1,DLG3,ELAVL2,GBX2,GPR17,HAS2,ITGA7,MDM4,MIA2,MT1M,NF1,PDE4A,EPN1,TNPO2,PTHLH,PTPRN2,RAD52,RGS4,RGS7,KCTD17,ZNF821,DOCK10,PREX2,SNCA,CDK19,TNS1,VAV2,VIPR2,EMSY,NT5M,NAV3,ZNF248" Drug 3855_DN 0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "AP2A2,AMPD3,GAS7,APOC1,NRP2,BMP7,BAIAP3,CAMK2G,C2CD2,ARHGEF10,SDC3,RIMS2,HDAC4,ARMCX2,RASGRP1,EGR3,FGFR1,GNG4,GRIK5,MYO7A,NF1,NPPA,NPR2,PCDH9,PFKFB3,RELN,SIDT1,PTPRE,RAB3IL1,ENOX1,ZMAT4,TRIM68,TCP11L1,EMID1,ZNF365,PREX2,SNCA,WDTC1,ST5,SYN2,MCF2L,WWC1,DICER1,TIAM1,FAM155A,NAV2,SSPN" Drug 7305_UP Econazole nitrate [24169-02-6]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "MRTFA,TRMT9B,ALDH7A1,CAPN3,HIP1R,MAP7,HOMER3,CSF1,VCAN,ARHGEF4,HDAC9,DNAJC6,MTSS1L,EZH1,DENND2A,GAD1,POLL,GNG4,GRM1,GUCY1B1,IFI16,SCIN,DIPK1A,KCNC1,MX1,PAK3,PALM,PBX1,FA2H,PRKAR1B,SAMD9,PTPRE,PEX5,RGS4,RGS10,KCTD17,TMCC1,THSD1,SS18,SYT11,KIAA1107,DOCK9,SLC35G2,TIAM1,TK2,WIPF1,ST7" Drug 2250_DN Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "NDRG2,KIDINS220,APC,BCAS1,ALDH4A1,SYNJ2,NEURL1,AKAP7,ABI3BP,ARHGEF4,SEC14L5,RIMS3,MFAP3L,EFNA3,SORBS3,ZNF589,FOXG1,GAB1,SRCAP,GLYR1,GRIK5,IGSF1,IL6ST,CNOT4,NPTX1,PTHLH,PTN,RAB3A,C1orf54,RGS10,CCDC25,SH3BGR,FNDC3A,SIRT2,SOX2,DOK5,PLCB1,SYN2,MCF2L,ARHGEF12,PCDHA6,TMOD1,TRIO,FAM155A,VIPR2,ZNF24,SPHK2" Drug 7525_DN daunorubicin HCl; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.28E-04 1.00E+00 6.62E-03 7.53E-02 47 191 "C1QTNF3,ARHGEF2,CDC27,FOXN3,LHX2,FADS2,QKI,ARHGAP32,KIAA0586,PARD6A,DLG3,DTNA,E2F5,FEM1B,EFNA3,MBNL2,EML1,PSRC1,GPR37,MAP4K5,ARHGAP19,BRINP3,MAP4,MEIS1,ADAM22,NNAT,NRCAM,PIK3R1,LRRC49,ELOVL2,MCMBP,ATXN1,KIF16B,FBXO11,KDM4B,SON,RAP1GAP2,AGTPBP1,TBL1X,TMPO,PARD3,RPRM,LMF1,WRN,ZNF184,NAV2,MPPE1" Drug 1004_UP trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.34E-04 1.00E+00 6.66E-03 7.57E-02 46 186 "ACHE,NDRG2,AMPD3,PPFIA3,ARHGDIG,CFLAR,BAIAP3,KYAT1,WHRN,LRIG1,ATRNL1,NOS1AP,RCAN1,SIDT2,LRRC23,GPR153,IQGAP2,SRCAP,GFRA2,GPM6B,GPER1,TJAP1,KCNH2,LSS,NEK1,NF1,SLCO1C1,PALM,PDE4A,SLC25A23,VPS13C,RAD52,RAVER2,SYBU,SHANK2,TSPYL2,CLSTN2,MAPK8IP3,VPS13A,POPDC3,TRIM2,TMOD1,VAV1,VIPR2,SCG2,SEMA3B" Drug 1612_UP "Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A" Broad Institute CMAP Up 9.34E-04 1.00E+00 6.66E-03 7.57E-02 46 186 "ADD3,BIN1,PPFIA1,APAF1,ARNTL,MARK4,ST3GAL5,SPAG9,RAB28,FEZ1,SLITRK5,PPP1R16B,CX3CR1,ZFYVE16,GSDME,RABGAP1L,SIDT2,MBNL2,ABI2,LPAR6,ENO2,EPS8,EXTL2,FGFR1,IFI16,KIF5C,MEF2C,NPPA,CCSER2,RETREG1,GPSM2,PACSIN1,MAPK3,CNNM2,PTX3,RPS6KA2,ZC4H2,CEP68,STXBP1,PJA1,CAMSAP2,RBFOX2,CA14,DNAJC12,ITM2C,RNF170" Drug 2857_UP Mycophenolic acid [24280-93-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.37E-04 1.00E+00 6.68E-03 7.60E-02 45 181 "ATM,CFLAR,CALB2,ARHGEF1,CRLF1,FOXN3,SOCS6,AKAP5,CSF1,PDE4DIP,ZNF337,SPOCK2,EFNB3,ING4,RASGRP2,FGFR1,FGFR3,CAMSAP1,FAM49B,OGA,GAD1,SESN1,RND1,GPER1,NR3C1,KCNH2,KHK,VWA5A,ADAM22,CNOT4,SERPINI1,SNRK,FAM120C,RAD52,KCNIP1,ZFP2,IL17RB,BCAN,SOX3,UNC5B,DMXL2,ZMAT3,FLRT2,PLPPR2,LAT2" Drug 2785_UP Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.37E-04 1.00E+00 6.68E-03 7.60E-02 45 181 "ASIC1,C1QTNF3,SLC4A4,ST3GAL5,SCAPER,CACNG1,CBFA2T2,TAOK2,ATRNL1,DCAF4,KIAA0513,DAPK1,GIT2,DMPK,TRAPPC9,SHANK1,DUSP9,OPTN,MBNL2,ELAVL3,LRRC23,CEND1,FDFT1,ZNF589,GFER,SLC2A6,HMGCR,ICA1,TJAP1,KCNH2,LSS,SLCO1C1,PIK3CD,C1orf54,KCTD17,ZNF821,SLC2A5,EMC1,HECW1,SPTAN1,CDK19,ARHGEF9,WSCD1,TRIM2,SEMA3B" Drug 2540_UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.39E-04 1.00E+00 6.69E-03 7.61E-02 42 166 "ABHD6,BIN1,APAF1,ARRB2,CFLAR,ST3GAL5,LDLRAD4,CFAP410,CD86,CD38,COL9A3,CREM,PDE4DIP,PPP1R16B,RUBCN,DOCK4,GSDME,FAM13A,ING4,PLEKHO1,BAIAP2,FHL1,CAP2,GLS,OLR1,PDE4B,PDE4D,SSH1,RETREG1,PTPRO,BSDC1,CLIP1,ATXN1,SEC14L1,ZNF821,SGK1,PALLD,SPTAN1,DNMBP,TPM4,TRPS1,CLDND1" Drug 2926_UP Zardaverine [101975-10-4]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.40E-04 1.00E+00 6.70E-03 7.62E-02 44 176 "TKTL1,BIN1,APBB2,FAM131A,PRX,DNAH17,SLC2A11,MYOM1,CD86,CD38,CHN2,CREM,MICAL2,SIPA1L1,PPP1R16B,CTNND1,DOCK4,SPOCK3,FAM13A,DLC1,BAIAP2,MDFI,SAMD14,ZNF862,NOVA1,OLR1,PDE4B,PDE4D,PFKFB4,CDK14,PGAM2,SERPINI1,TCP11L1,BCAN,RPH3A,PALLD,BEX1,SPTAN1,PCDHA5,ZFPM2,TNS1,SEZ6L,ZBTB38,KAT6A" Drug 3102_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.40E-04 1.00E+00 6.70E-03 7.62E-02 44 176 "ADORA3,BIN1,ANK3,AQP4,DNAH17,MPDZ,USP2,NEURL1,ARHGAP33,CHI3L2,CHN2,CREM,CSNK1E,NCAN,EDRF1,RIPOR2,DAPK1,BRINP1,MFAP3L,RCAN1,CELSR3,DLC1,FGFR1,FGR,CAMSAP1,KCNMB4,GNG4,KLF12,VSIG4,SCRG1,ITIH2,ITPKA,KHK,PDE1C,MARCH1,ABLIM3,SLC11A1,SLCO1A2,SAMSN1,TACR1,TEK,TK2,PIK3R5,ZBTB16" Drug CID000060860 metaiodobenzylguanidine Stitch 9.47E-04 1.00E+00 6.74E-03 7.67E-02 10 22 "CBFA2T2,ENO2,MCHR1,BCO1,MYCN,NPPA,SST,SSTR1,SSTR2,SMUG1" Drug CID000445682 Fe-mo-s Cluster Stitch 9.47E-04 1.00E+00 6.74E-03 7.67E-02 10 22 "CSF1R,GRIA1,GRIA2,GRIA4,GRIK5,GRM8,MITF,ENPP2,ARHGAP9,RASD2" Drug CID000444878 carboxymethyl-CoA Stitch 9.47E-04 1.00E+00 6.74E-03 7.67E-02 10 22 "ABHD6,CLTB,CS,DHRS4,MT3,PCSK1,PKM,PLCD1,SYNE2,NR2E1" Drug CID000126186 6 mEq Stitch 9.47E-04 1.00E+00 6.74E-03 7.67E-02 10 22 "SLC12A5,EDNRA,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIK1,SLC12A2" Drug CID000445522 H-Mn Stitch 9.55E-04 1.00E+00 6.80E-03 7.73E-02 22 71 "ALS2,DYNLL1,MTMR2,CHM,DCTN1,ATL1,BSCL2,TUBA1B,GPR162,TXNL4A,TUBA1C,HMX1,IL6ST,JAK1,MSI1,PMP22,PRPH,CLIP1,SLC12A4,ZFP91,NPL,TUBA1A" Drug CID000002460 "dibutyryl cyclic 3',5'-AMP" Stitch 9.59E-04 1.00E+00 6.82E-03 7.76E-02 116 561 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,APOC1,APOC2,APP,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ALDH7A1,RGS11,CDK5R1,CACNA2D1,CALM1,CCK,USP2,RGN,SCARB1,LRBA,CHGA,CHRM1,MYL6B,PCYT1B,AKAP6,COL4A5,LETMD1,CPS1,CREM,CSF1,BOC,DBT,CALN1,EDN1,EDN3,ENO2,FCGR1A,FGF1,ACTL6B,TPK1,GALC,GAP43,GPR162,GFAP,CRCP,GLUL,GNAS,GPD1,TNFAIP8L3,IGF1,IGFBP1,IL12A,ITGAM,KIT,LAMA2,MAG,MAP2,MBP,MMP16,MMP17,MYCN,MYL3,NEFM,NEFH,NFIA,NPPA,HCN1,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PENK,PKD1,FTO,SPATA6,FA2H,PTPA,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,LAMA1,PTAFR,PTHLH,PYGM,RAP1GAP,MAPK12,SLC1A2,SLC1A3,TMCC1,SST,APOM,LEFTY2,TGFBR3,ACTR6,TRH,TMPRSS5,TTPA,PLD4" Drug ctd:D008344 Maneb CTD 9.60E-04 1.00E+00 6.84E-03 7.78E-02 77 348 "ACHE,ADORA1,APBB1,ASCL1,RIPK1,ADGRB1,BID,CDK5R1,CACNA1E,CALM1,DGKI,NOG,ADGRG1,CLU,NIPBL,FEZ1,DBI,ARNT2,DNM2,DNAJB6,HEYL,EIF4G2,ENO2,LRRC17,TUBA1B,PTK2B,FGFR3,SEMA4D,ATP8A2,CPLX1,HBA1,HNRNPK,HSP90AA1,IDH3A,IGF1,ITGAM,KCNA2,KCNMA1,KIT,STMN1,LIFR,MAP2,MAPT,MBNL1,MDM4,MEF2C,ADAM22,FXYD6,NDP,NEUROD1,NFE2L2,NTRK2,PAX6,PDE1B,PDGFRA,PDYN,PRKCZ,MAPK3,RPS6KA2,LRRK2,SLC8A1,SIRT2,CCDC88A,CDK5RAP2,SNCA,ZHX3,KIF1B,SYT5,TEK,SIRT1,HEY2,TNR,UBC,UCHL1,TUBA1A,RTN4,AP3B2" Drug ctd:C517284 monomethyl phthalate CTD 9.63E-04 1.00E+00 6.85E-03 7.80E-02 186 957 "ARID1A,ADCY6,ADORA1,ADRB2,AK2,BCAR3,ALK,DOC2A,BIN1,ANK2,PARG,KCNAB2,APC,ALS2,CDK10,ARHGAP5,CADPS,ATP1A2,SLC4A4,ALDH7A1,B3GALT2,PROM1,ST3GAL5,BTK,CA12,CACNB2,CH25H,CCK,RGN,CD38,CDK11B,CDC27,CDH2,NOG,CFL2,SLC22A6,CLCN3,ABCG2,COL9A3,CP,NCOR1,NCOR2,OSBPL3,SDC3,CTNND1,HDAC4,DCT,KIAA0319,SLC12A6,DPP6,DRD1,DYRK1A,ABCC5,EEF1A2,OPTN,PLXNC1,IRAK4,COPS4,EN2,OLIG2,ERBB2,FABP7,EFEMP1,ST3GAL6,CHST15,FER,VTI1B,FOXO3,FLT1,PDLIM5,ATP6V1H,TBR1,DOT1L,GAB1,TRAF3IP2,GALR1,ACSS1,SULT1C4,GDF9,CYP46A1,GHR,GJB1,COPS8,GLI2,POLL,GRIA1,PLCD4,GSN,GUCY1A1,ATOH8,TOX2,HRH3,HMGCR,TLX1,HSD17B1,IGF1,HES5,INPP1,ITGA7,KCNA2,KCND1,KCNJ3,MAOB,MAT2A,MMP17,NAP1L1,NELL1,NEUROD1,NPR2,NPTX2,SLC11A2,NUCB2,PAH,PC,PCDH8,PCSK1,PDE4D,PKM,EXOSC10,POLR2F,PPARA,MED1,MAPK4,MASP1,RAD17,RAD51D,RAD52,RET,PBRM1,FBXW7,MCMBP,LRRK2,LGR4,CLIP1,MAPK12,SCN2A,SCN8A,TNFRSF19,SOX6,TRA2B,SLC1A3,SMTN,SLC6A1,SLC9A5,SLC12A2,SLC12A4,SLC15A2,SMARCE1,SNAP25,TRERF1,SOX11,KDM4C,SPTB,KIF1B,SSTR1,LRRC4,MPRIP,SUPT5H,ARC,SYP,SYT1,TACC1,ATMIN,TCF12,SLC19A3,DICER1,SIRT1,THRA,TIAM1,PARD3,CABIN1,TPM3,NR2C2,TRPC3,TSC1,TST,SGK3,AMOT,VAV2,BEST1,P2RY12,ZIC1,PMEPA1,SLC38A1,FXR1,IFT88" Drug CID000005537 trequinsin Stitch 9.86E-04 1.00E+00 7.01E-03 7.98E-02 19 58 "ADCY5,ADCY6,ADCY8,ADD3,ALDH7A1,CALM1,ABCC5,FGF1,PTPN5,HP,HPR,PDCD2,PDE1C,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,ABCB1" Drug ctd:C483909 torcetrapib CTD 9.90E-04 1.00E+00 7.04E-03 8.01E-02 76 343 "ANK3,EP400,APBB2,CASK,ATP2A2,DST,CAMK2D,LONRF2,HECTD1,AHCTF1,CREM,RBM39,APPL1,CTH,EDRF1,PYGO1,CYBB,TCAF1,GIT2,DBT,EDN1,FSD1L,MBNL2,EIF4G1,AFF2,PDLIM5,HTATSF1,NR3C1,IFI16,C5orf24,IL6ST,JAK1,MAP4,KITLG,POC1B,MITF,MKLN1,MYO6,AMZ2P1,NFE2L2,PDE4B,PDE4D,CDK14,ZNF655,CCSER2,LRP12,ING3,TNPO2,PRKACB,VPS13C,RBBP6,EXD2,UEVLD,ZNF331,CSRNP3,MRAS,CHD9,CCDC88A,CPEB4,PALLD,ERC1,ITPRID2,PRRC2C,TACC1,EHBP1,TCF4,TRIM2,PMS2CL,TP53BP1,RBFOX2,TPM4,TTC3,DNAJC12,FLRT2,SLC30A4,ZNF37BP" Drug CID000003891 AC1L1GXW Stitch 1.00E-03 1.00E+00 7.12E-03 8.10E-02 27 94 "MYH7B,NUMB,SEPT7,CDC27,CDC42,MAGI1,DLGAP1,NUMBL,CLTC,DBN1,DLG4,DNM2,SHANK1,DNM1L,F8,ACTL6B,FHL1,SYT3,ATE1,SYNPO,HSP90AA1,SCIN,MYO5A,ANLN,PDLIM2,ACTR6,SYNPO2" Drug CID000001927 9-HODE Stitch 1.03E-03 1.00E+00 7.27E-03 8.28E-02 37 142 "ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,AGT,APC,COL4A5,NCOR1,NCOR2,ABCG1,CSF1,HDAC9,HEPH,E2F5,E2F6,PIPOX,PNMA2,PPARGC1A,GPD1,GPD2,GRIA1,GRIA2,GRIA4,GRIK5,GRM2,GRM3,OLR1,PPARA,MED1,RXRA,RXRG,TCF12,SIRT1,TPM3,NETO1" Drug 1778_UP Berberine chloride [633-65-8]; Up 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ACTN1,ADAR,PLA2G6,APOC1,N4BP2L1,MTMR3,CA12,P2RX6,CHI3L2,CHN2,SLIT2,PICK1,IQCK,PCYT1B,COL9A2,OSBPL3,MED12,EEF1D,RBM12,PIPOX,FYB1,HIGD1B,AHDC1,ADAM28,RUNDC3A,CRCP,GPR12,SCAMP5,MOBP,LYRM9,NPPA,PDE3B,NLE1,PLTP,DEF8,RGS12,RNASE1,TCP11L1,NTNG1,PREX2,FAM214B,IZUMO4,ST5,TLR4,SMUG1,TRPS1,ZNF142,STMN4" Drug 1721_UP Ceftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABAT,NDRG2,ADD2,AMT,CNTNAP1,APOC1,BACH1,BMP7,NEURL1,TAOK2,CLCN3,DNAJB5,CRY2,CRYM,INTS1,EFNB3,STX2,DPYSL4,POMT1,TDRKH,NR3C1,MYT1,NEFH,NTRK3,OCRL,OPRL1,CCSER2,GPSM2,PLEC,CDIP1,MBOAT7,MAPK10,DEF8,CCDC40,RNASEL,ATF7IP,WDTC1,ZCCHC24,DBNDD2,NXT2,PDLIM2,TK2,PARD3,RBFOX2,ZMYND8,ZNF32,MARCH8,CAMK1G" Drug 2931_DN Tocainide hydrochloride; Down 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,MRTFA,PKP4,MARCH3,SCAPER,ARHGEF1,LHX2,EPS15L1,CSF1R,OSBPL3,DGKG,GSDME,RABGAP1L,EXOG,PCOLCE2,KIAA1109,CSPG5,FYB1,COPS8,GLYR1,GSN,AGFG1,LAMA2,MATK,MEF2C,NEK1,CNOT4,PCDH9,PIK3R1,PTPA,RAD52,RET,MCMBP,SLC2A5,ARHGEF40,PALLD,ZC4H2,MAPK8IP3,STX1A,KAZN,EXOC7,CAMSAP2,ZEB1,SYNE1,AP4E1,XRCC4,MAP3K12,PRDM2" Drug 6204_UP Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,ADCY6,AP2A2,GAS7,CADM3,BCL7A,BMP7,SCAPER,MTMR3,KYAT1,NEURL1,LRRFIP1,FAM189A2,CSF1,DAPK3,MFAP3L,ATN1,DSCAM,EBI3,LRRC23,F3,EFEMP1,PRELID3A,FYB1,POLL,GNG4,GPM6B,GRM8,IL6ST,MEIS1,PDE3B,WDR25,RALGDS,RASA3,ITSN1,SMTN,PKNOX2,BTBD7,CEP68,PHLDB1,TK2,ZMYND8,PLPPR2,MICAL1,ZNF711,MPPE1,UBE3B,PHTF2" Drug 5402_UP Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "FAM135A,MRTFA,AMPD3,CDC42BPA,GAS7,PDE8B,PTCH2,CFLAR,MTMR2,CFAP410,CAMK2G,CHRNB2,CNTNAP2,RIMS3,DMPK,DRD1,HIPK3,DMTN,NRN1,FGF1,HPCAL4,AGAP2,ZMYND11,USP19,POLL,GRM3,NXPH3,ITIH2,KCNN1,LMO1,MDFI,MYO7A,NDUFA5,PDE3B,PENK,PRKCB,SNRK,PTN,CCDC40,ZNF493,ASIC4,RASA3,CPEB3,FBXO11,SHANK2,MICAL1,WNK1,KCNAB1" Drug 2334_UP Riluzole hydrochloride; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MRTFA,AMH,ARRB1,MARK4,NCOA1,DDX3Y,N4BP2L1,RIPK1,SYNJ2,CAMK2B,HIP1R,CD38,CREM,PPP1R16B,TOX,GSDME,EDN3,SIDT2,ABI2,COQ7,ERBB2,KIAA1109,FHL1,INPP5K,LILRA2,GRB10,VWA5A,ADAM22,NOVA2,GDPD2,KHDRBS2,RET,GSTCD,TRAPPC13,MRAS,FAM102A,BCAN,KDM4C,RAP1GAP2,ACSBG1,VAMP1,WSCD1,TCF4,PSD3,CDK20,FLRT2,WNK1,SLC17A7" Drug 3336_DN Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "LTBP4,AMT,ANK3,APBA2,CDK10,MARK4,ASPH,MPDZ,BTRC,SCARB1,ZFYVE9,HOMER3,CNTN1,CRY2,GREB1,EDRF1,DAPK3,KBTBD11,DTNA,MRNIP,HBS1L,SRCAP,USP19,GLS,GNG3,GRB10,KHK,CNOT4,CDK18,PLCD1,PRKAR1B,RGS12,GSTCD,SH3BP2,SYBU,ABLIM3,BTBD7,ZCCHC24,SPTAN1,KAZN,MCF2L,CRTC1,TMOD1,CDK20,CADM1,LMF1,KCNK12,HPS4" Drug 4106_UP "Azathymine, 6 [932-53-6]; Up 200; 31.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "DPF1,ACTN2,ARRB1,SYNJ1,CHRNB2,CRY2,NCOR2,TENM4,ARHGAP24,KIAA0319,DYRK1A,EDN3,EDNRB,EFNB3,PLXNC1,FUT9,GAD1,RND1,GNAO1,GPM6A,GRIN2C,GRM8,GSTM5,ICA1,KCNK2,VWA5A,MAOB,MSI1,MX1,SLCO1C1,OMG,PURG,PACSIN1,PRKCB,VPS13C,ZSCAN2,TRIM68,TMEM206,SCN8A,CNKSR2,PKNOX2,SMARCD3,KIF13A,DOP1A,SOX10,SP4,DOCK9,PRDM2" Drug 7283_UP Norfloxacin [70458-96-7]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "APC,KIF1A,KSR1,CACNB4,CHGA,RAB28,DNAJB5,HAPLN1,CSF1R,AASS,CDKL3,EFEMP1,FYB1,ZNF44,GAD1,SEPT9,GPM6B,LPAR4,IRAK3,KCNC1,KCND3,LSS,MAPT,MGAT3,AFDN,PDE4D,SAMD9,PLPPR1,KHDRBS2,RGS3,SCN2B,MRAS,FRMPD1,AMBRA1,SLC6A9,WDTC1,SOX2,KDM4C,TEK,SPX,THRA,PIK3R5,TRO,OSBP2,VIPR2,XRCC4,REEP1,KCNAB1" Drug 6078_DN Trioxsalen [3902-71-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,SLC12A5,ADRA1D,NME5,BIN1,APBA2,CADM3,ATP6V0A1,RIPK1,CDK5R1,MTMR3,CACNA1I,BTRC,NEURL1,HOMER3,CSNK1E,PDE4DIP,DOCK4,MFAP3L,KBTBD11,DTNA,DUSP9,STX2,FOXG1,DISC1,POLL,RASSF8,KCNJ3,KCNMA1,KPNA5,MAP4,MID1,MMP16,MPP2,NF1,MBOAT7,MAPK7,PRPH,PTN,RAD52,SH3BP2,SLC20A2,WDTC1,SPART,TACC1,KIAA0930,PCDHA6,TMEM121" Drug 2103_UP Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,ARID1A,PLA2G6,LGR5,LARGE1,CLCN4,ABCG2,CPS1,FAM169A,SLITRK5,DAPK3,SMG7,PLXNC1,ANKMY1,FGF1,TRAF3IP2,SEPT9,GLYR1,FERMT2,CACFD1,BACH2,ICA1,MEIS1,MMP16,MYO7A,PAK3,PBX1,CDK14,SERPINI1,FAT4,ZCWPW1,RGS10,FBXW7,SCN8A,DZIP1,ZKSCAN3,SLN,ZHX3,IQSEC2,ZBTB43,DDN,SAMSN1,PRRC2C,ASTN2,IQCE,TK2,ZBTB14,MAP3K12" Drug 4285_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,ALK,AMPD3,PKP4,EPB41L5,ADAM23,MTMR3,CDO1,DNAJB5,SULT4A1,IFFO1,DCT,ATN1,MRNIP,LRRC17,FOLR2,ALDH1L1,HTATSF1,GRM1,VSIG4,HTR2A,KCNQ3,MAP4,MARK1,MMP16,FXYD7,OMG,PCDH9,PDE4D,PFKFB4,NECAB2,MAPK10,RAD52,ZCWPW1,KCTD17,CNKSR2,SLC11A1,UNC5B,MLC1,SYN2,ADGRL3,TEX15,ZFPM2,TMPO,CDK20,CADM1,VIPR2,WNT7A" Drug 1240_DN 2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "CDC42BPA,APAF1,ARHGEF7,FUBP1,MTMR3,NIPBL,HOMER3,CDC42BPB,CREM,HINFP,DZIP3,SDC3,PPP6R2,DCAF8,TM9SF4,ZNF804A,EDN1,SIDT2,SORBS3,COQ7,FGF1,BAIAP2,TRMO,ATP2C1,GBX2,PRRC2B,MUM1,DHX35,MATN3,NDP,NUMA1,PC,PDE4B,CCSER2,STRN3,FAM120C,KIRREL1,SH3BP2,AMBRA1,LIMCH1,SNCA,STX1A,CHST8,CBX5,PARD3,UPF3A,NUP214,SENP7" Drug 7504_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NME5,CDC42BPA,CDK13,IL33,KYAT1,CHRNB2,CLU,MYRIP,TBC1D5,SMG7,ATN1,DTNB,FEM1B,FCF1,TENM1,MRNIP,ETV1,FHL1,PDLIM5,ALDH1L1,RND1,MSL3,IL6ST,PCDH9,RETREG1,MAPK8,PRPH,PEX5,CCDC40,ARHGEF10L,TTLL7,MCMBP,ZNF821,MRAS,SLC14A1,TNIK,ZBTB43,ATP10B,POGZ,SYT1,TIMP4,TK2,TNS1,TRIO,HIRA,VGF,ZNF74,SYNC" Drug 7502_UP CP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ALAD,LTBP4,MRTFA,CDC42BPA,APC,GAS7,ALDH4A1,HOMER3,CNTNAP2,HDAC9,CDON,ABI1,DTNA,EDN1,CNNM1,TNK2,LRRC23,FGFR1,FYB1,SYT17,SLC2A6,ATXN2L,TAGLN3,NF1,NFIX,CDK18,PDE4D,RC3H2,POLG,ZSCAN32,TMEM231,ZNF671,FAM192A,FUZ,SLC22A4,IQSEC2,VPS13A,ASTN2,IQCE,SMG6,DNAH7,R3HDM1,CABIN1,FAM155A,LMF1,TFIP11,PLSCR4,ACTR3B" Drug 6754_UP Fusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADORA1,ALK,GAS7,SEMA4G,SLC4A4,DLGAP1,COL9A3,TCEAL2,PPP6R2,JAKMIP2,SV2A,EDN1,TENM1,FGFR1,HPCAL4,FOXG1,C1orf61,FLT1,EFCAB2,GAD1,KCNMB4,GNG3,PRUNE2,TDRKH,IGFBP1,IL6R,KCNJ3,PACRG,MAG,MAN2A2,MDFI,CLDN11,PALM,PROX1,CCDC40,C1orf54,KCNIP2,SLC20A2,SLCO1A2,HECW1,ATP10B,DNAH7,CABIN1,TPM1,TRPC3,REEP1,EMSY,STMN4" Drug 2692_UP troglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MTUS1,ASCL1,ALDH4A1,AZGP1,CACNB4,EPS15L1,NRXN2,NCOR2,ARHGEF10,VCAN,PDE4DIP,DGKG,PARD6A,EDN3,AFF2,EFCAB2,CSPG5,SIGLEC8,GPD1,GSN,ATXN2L,HPCA,KCND3,MID1,MOBP,MSR1,LYRM9,PCDH9,PPARA,MAPK7,PTHLH,PTH1R,ZSCAN2,RAB3A,CCDC40,RASGRF1,SUGCT,EMID1,SLN,PHF24,AHCYL2,ZNF34,TPM1,CA14,TUBB1,ZNF225,EVI5,CAB39L" Drug 3029_DN Dimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ARID1A,MTUS1,BCAR3,BIN1,AZGP1,KSR1,CDK5R1,SYNJ1,CACNB2,CHM,RUBCN,SMG7,EXOG,CELSR3,PLXNC1,ELAVL3,FCGRT,FHL1,ZMYND11,SEPT9,INPP5K,WASF3,GPM6B,LILRA2,TJAP1,JAK2,SMAD1,NEK1,NFYA,NINJ2,CNOT4,SERPINE2,LRP12,POLG,TRAPPC13,MAPKBP1,DOP1A,NSFL1C,PLCB1,KIAA1107,DMXL2,TCF7L2,TNS2,TPD52,TRPS1,ZKSCAN5,ZNF225,KCNAB1" Drug 3187_UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "RALGAPA1,ACTN2,AMH,APOC1,ARHGDIG,SLC2A11,CACNA1D,INA,CBFA2T2,CLCN4,NMT2,STOML1,PDE4DIP,DNAJC6,ING4,ACSL4,FGF12,HPCAL4,FOXF2,AGAP2,GPM6B,KCND2,PAH,PIK3CD,PLCD1,PDZRN4,MINDY2,CEP41,FAM120C,S100B,CCDC88A,SHANK2,SLC12A4,SORCS3,KDM4B,KIF21B,TACR1,DOCK9,PCDHA2,GPR161,TGFBR3,R3HDM1,VSNL1,WIPF1,SLC13A3,XRCC4,EPM2A,AP3B2" Drug 7241_DN Mesalamine [89-57-6]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "CDC42BPA,EPB41L5,ALDH4A1,ATM,SYNJ2,VAX2,HOMER3,ARHGEF6,LRIG1,PDE4DIP,DCTN1,LYPD1,RABGAP1L,CDON,EGFR,MBNL2,ENO2,DENND4A,F3,FOXG1,FAM49B,DISC1,SRCAP,IL6ST,INPP5B,MPP2,CNOT4,RETREG1,PLEC,MBOAT7,PRKAR1B,RIPOR1,SBF1,MAPKBP1,WDTC1,KDM4C,ZBTB43,CLASP2,ARHGEF9,TCF7,ZMYND8,MICAL1,MAP3K12,NAV2,MVB12B,SMIM8,ZNF248,TIGD6" Drug 7066_UP SB 203580; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "APBB2,APP,CDK13,MARCH3,NCOA1,SCAPER,ENTPD4,SH2B1,VCAN,RIMS3,EDIL3,EFNA3,FAM13A,EGFR,SORBS3,TUBB4A,TESK2,FGFR1,SCARA3,OGA,FYB1,FYN,DENND2A,USP19,GLRB,KCNMB4,FICD,SLC2A6,MIA2,SCAMP5,TAGLN3,PC,PLXNB1,CDIP1,MED1,MAPK7,RAB3A,FAM184A,ZFP30,FUZ,KIF13A,SPTAN1,ZBTB43,ATP11A,DNMBP,TNS1,MAP3K12,PRDM2" Drug 6621_DN Lysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "CDC42BPA,ATM,CFLAR,MYRF,SCARB1,HOMER3,CPS1,CREM,NCOR2,ABCG1,SIPA1L1,RUSC2,PLEKHO1,EPB41L1,EPHA5,ST3GAL6,ANKFY1,ERAP1,SRCAP,GLS,POLL,NR3C1,SHISAL1,IL6ST,MIA2,MMP16,NDUFA5,PAK3,NLE1,SH3TC2,ZNF821,SH3GL2,ASAP3,FBXO11,BCAN,ELMO2,KDM4B,CLASP2,SS18,NCDN,MAPK8IP3,SEPT8,ASTN2,SMG6,CABIN1,NR2C2,NAV3,EPM2A" Drug 3355_DN (+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MRTFA,DOC2A,APLP1,APOC1,PDE8B,MTMR3,GYG2,CA4,CBFA2T2,RAB28,FADS2,WHRN,ENTPD4,CRY2,DCAF4,EDRF1,RABGAP1L,DTNA,HSD17B14,SEMA4D,DPYSL4,SYT17,SRCAP,ZNF276,GLS,GNG3,CNTRL,CACFD1,MIA2,ADAM22,CDK18,SERPINE2,SLC25A23,RPS6KA2,ZNF821,SH3BP2,EPN2,SLC6A8,IQSEC2,TROVE2,THSD1,ST5,FBXW11,SLC44A1,TRPC1,WIPF1,XRCC4,ST7" Drug 1975_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "PLA2G6,OGT,PPFIA1,KCNAB2,SEMA4G,N4BP2L1,RUNX1T1,TBRG4,FOXN3,EPS15L1,CLCN3,CYBB,GIT2,SPATA2,KIAA0753,DTNA,SIDT2,PHF20L1,RASGRP2,OGA,BTN2A1,HNMT,MAP4,MBD1,MITF,GIT1,MYO5A,SETD4,KCTD15,MED1,TMEM231,RGS10,NEK11,SATB1,BCAN,SLC11A1,SCMH1,ZKSCAN3,WDTC1,ZSWIM8,MPRIP,DIP2A,MTMR14,KAT6B,PIK3R5,RBFOX2,TPD52,LAMP5" Drug 6240_DN Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADD1,BRAP,MTUS1,CDC42BPA,PKP4,APP,OSGIN2,MAP7,KRIT1,ZMYM4,DCAF8,ZNF337,INTS1,GIT2,DLG3,RBM12,SH3GLB1,RACK1,KIAA1109,SEMA4D,PDLIM5,CGREF1,ZNF276,MIA2,PMP22,PPP5C,PRKACB,PTK2,REV3L,ROBO1,ITSN1,AMBRA1,PEX26,ELMO2,SMARCC2,KDM4B,SPATA7,SS18,AGTPBP1,TCF7L2,PSD3,ATP13A2,ZNF106,TIAM1,RBFOX2,VAV1,CLDND1,C12orf4" Drug 3455_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,AP2A2,ALDH4A1,B4GALT6,SLC4A7,CRY2,CSNK1E,PPP6R2,GPRASP1,KIAA0586,GIT2,PARD6A,E2F5,FEM1B,SUGP2,IRAK4,ECSIT,SEMA4D,PDLIM5,GALC,GLUL,RNFT2,HNMT,KCNJ3,CNOT4,PC,ELOVL2,NEK11,FBXW7,NUBPL,ABLIM3,BTBD3,IFT122,TROVE2,LARP4,KLHL7,PLCB1,TACC1,SEMA4A,TRIM2,TMPO,TRPC1,HIRA,UBTF,VAV2,LMF1,CLDND1,PHTF2" Drug 5087_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADRA1D,KCNAB2,ASPH,STX16,CACNA1A,CANX,KIAA1549L,ARHGEF4,DAPK3,EDIL3,HIPK3,FCF1,EN2,ETV1,SCML2,KIAA1109,ANKFY1,DLL3,GART,GPD2,HNMT,AGFG1,DHX35,HSF2,SCIN,INPP5B,KCNN1,NDP,CNOT4,NUMA1,STRN3,MAPK7,KLK6,SH3BGR,ZFP30,SNCA,TMCC1,PEG10,SS18,TCF4,OSBP2,WIPF1,ZNF74,ZNF225,EVI5,MPPE1,PHTF2,RNF170" Drug 4832_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,BAIAP3,CAMK2B,CACNA2D2,AKAP7,FAM169A,DBT,HP1BP3,CDON,DTNA,EDNRA,EIF5,TNK2,NCALD,ANKMY1,SCML2,FER,FGFR1,MSL3,GNG4,STON1,GPER1,HNMT,HSF2,INPP1,KCNH2,KIF2A,NPR2,OPA1,PDE3B,TNPO2,PPARA,PPP5C,ELOVL2,FAM184A,GTDC1,RGS12,CCDC25,SLC1A7,BTBD7,SLC20A2,CXXC4,SNCA,WDTC1,SOX2,RGL1,TCF7L2,TNS2" Drug 605_UP monastrol; Up 200; 20uM; MCF7; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,LTBP4,BIN1,ANK1,APBB1,KIAA1614,ARRB1,ARRB2,CADM3,HIP1R,ARHGEF6,PCYT1B,DCT,EDNRA,FAM13A,EIF4G2,ELN,STX2,GNAO1,GPR19,MCHR1,GRIN2C,GRM1,PADI2,HAPLN2,AGBL5,KCNMA1,MAPT,KITLG,NTRK3,PDE1C,GPR173,PNMA3,PTCH1,PTPRD,CCDC40,ZFHX4,FNBP1,HECW1,PSD3,TEX15,CDH22,PARD3,TMPRSS5,CA14,SPHK2,TFIP11,GDPD5" Drug 4161_UP Cefadroxil [50370-12-2]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ALK,ANK1,APC,CDC14B,CFLAR,SYNJ2,BAIAP3,CCKBR,CDO1,AKAP7,AKAP6,SUSD5,VCAN,ARHGAP24,HEPH,DMD,DTNB,EDN1,VPS13B,ERBB2,F5,FAM49B,OGA,FYB1,GFER,RUNDC3A,GNAO1,GRIK1,GUCY1A2,KLF12,MOBP,KCNK10,PDE4D,ENPP2,CDK14,PTPRD,PPP1R9A,CNKSR2,SLC1A3,PKNOX2,IZUMO4,SPTB,CRTC1,TEX15,TEK,CLIP2,XRCC4,AP3B2" Drug 1560_UP Fipexide hydrochloride [34161-23-4]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,BEGAIN,ARNTL,BMP7,SCAPER,HAP1,P2RX6,SLC24A2,PICK1,SEC31B,ENTPD4,FEZ2,SLITRK5,KIAA0586,EPHB1,STX2,IGSF6,ANKMY1,ECSIT,TRMO,TPK1,TRAF3IP2,PCSK1N,ADAMTS13,IL6R,KIF5C,NFYA,P2RX7,PDE4B,PLCD1,SLC25A23,POLR2F,RLBP1,RNH1,TCP11L1,SH3BP2,ITSN1,SLC11A1,ZC3H13,MLC1,FAM208A,TCF4,OBSL1,KAT6B,TRPS1,CA14,GORASP1,STMN4" Drug 3463_UP Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ALCAM,LTBP4,AMPD3,APOC1,PPP4R4,ARHGDIG,CACNB2,RCBTB2,ZFYVE9,SLC4A8,EDRF1,DCAF8,DUSP9,EGFR,VPS26C,FGFR1,SEPT9,NR3C1,HNMT,JAK2,KCNF1,MMP17,NF1,NNAT,NTRK2,NUMA1,CLDN11,PENK,PRODH,ELOVL2,RALGDS,ZDHHC14,RGS12,ZNF821,ASAP3,ANKRD6,FAM214B,BTBD7,SPTAN1,PHLDB1,VPS13A,EXOC7,KIAA0930,UBE3A,VLDLR,PRDM2,MPPE1,TIGD6" Drug 1367_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ACADM,SHROOM2,ARRB2,ATP2B1,BACH1,OSGIN2,WASF1,CA12,CAST,KRIT1,SRSF11,RAB28,SOCS5,PPP6R2,RUBCN,HDAC9,ZEB2,FBXL5,C2CD2L,DLG3,SRPK3,VPS26C,ACSL4,KIAA1109,SEC23B,EFCAB2,ERAP1,GART,CRCP,PADI2,HNMT,KTN1,MARK3,PDE1C,PDE3B,ENPP2,RETREG1,PPM1B,EXD2,SCP2,CHD9,KBTBD4,GLT8D1,TTBK2,KLHL7,CADM1,EVI5,JMJD1C" Drug 6563_UP PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ARID1A,APBA2,ASPH,NRP2,CFAP410,CA12,ARHGAP22,CLCN4,CSF1R,CSNK1E,SDC3,SMG7,APH1A,CAMSAP1,SEMA4D,CAMKK2,CELF1,TMEM8B,GPER1,CACFD1,PADI2,MMP16,MN1,GIT1,NNAT,SMOX,MAPK10,PTPRH,ATG16L1,RGS10,KIRREL1,MAPK12,OGDHL,SPTAN1,MAPK8IP3,SYT1,TRIM2,ARHGEF12,DICER1,PARD3,CABIN1,ZMYND8,HIRA,WIPF1,LAT2,EMSY,HPS4,ACTR3B" Drug 6867_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ASPHD1,PLA2G6,MARCH3,ADAM23,CACNA2D2,RCBTB2,SOCS6,CHI3L2,QKI,IQCK,PDE4DIP,DAPK3,SMG7,ARNT2,RCAN1,LPAR6,ARMCX1,PTK2B,BAIAP2,PDLIM5,TRAF3IP2,GBX2,POLL,CNTRL,GRM1,MAP4K5,KCNMA1,NDP,NFYA,OCRL,PDE4A,PDPK1,FSD1,MAPK7,SYTL2,SBF1,BTBD7,CDK5RAP2,ZNF415,KDM4B,SPTB,LHPP,DICER1,BEX4,RBFOX2,LMF1,ZNF74,SEMA3B" Drug 3708_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MTUS1,ADGRF5,PKP4,APC,CDC14B,MARCH3,ATM,CFLAR,SOCS6,ENTPD4,SH2B1,PDE4DIP,SLITRK5,SMG7,AK5,HIPK3,CDKL3,FGFR1,SEMA4D,MARK1,GIT1,ZNF862,EPN1,RC3H2,CEP41,CNNM2,RGS3,RGS7,ZNF671,KDM4B,WDTC1,SPTB,IQSEC2,ZBTB43,THSD1,IQCE,TMEM121,GPR161,CABIN1,TRIO,ZMYND8,VAV2,MICAL1,SF1,ZNF74,TFIP11,EVI5,KAT6A" Drug 2643_DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,ATM,CFLAR,SYNJ2,SCARB1,ZFYVE9,DBT,SMG7,EFNB3,SORBS3,FER,BAIAP2,FAM49B,GRIK5,HNMT,DHX35,LIG4,MBD1,NACA,NFYA,PDE3B,PIK3R1,PMS2,WDR25,PSMD13,RAB3IL1,CEP97,RAD52,ZDHHC14,ROM1,ZNF821,SH3BP2,ELMO2,RCOR3,ZHX3,ATP11A,TBL1X,CRTC1,TK2,TPD52,ZMYND8,HIRA,XRCC4,ZNF74,TFIP11,WNK1,EMSY,HPS4" Drug 5884_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG3,KIDINS220,APP,PDE8B,MARCH3,BCL2L2,CFLAR,SPAG9,LRRFIP1,CNOT8,DAPK3,DBT,PLXNC1,EIF5,IRAK4,EML1,COQ7,CDKL3,ETV1,F8,FHL1,GART,ZNF276,PRRC2B,MAP4K5,DIPK1A,INPP5B,MAPT,MITF,MPP2,NFYA,SLC11A2,CCSER2,ZNF426,PID1,TTLL7,FNDC3A,RAB3GAP1,SMARCA4,SNCA,TEX2,EXOC7,TBL1X,NR2C2,AMACR,PLPPR2,MAP3K12,PLSCR4" Drug 5001_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "APBB2,CDC14B,DNAH17,INA,MYRIP,NCOR2,ARHGEF4,ST8SIA3,EDN3,SGK2,TNK2,ELN,KCNMB2,CORO2B,KIAA1109,FGF13,FOXG1,OGA,GABRA2,SRCAP,GRIK5,KCNJ5,KCNQ3,ADAM22,MX1,NF1,PCSK5,PIK3CD,MTRF1L,PRKAR1B,MAPK8,PTHLH,FAT4,KLHL11,MYH14,PNMA8A,TCP11L1,PKNOX2,SNAP25,ZC3H13,ARHGAP26,ATP11A,WSCD1,THRA,TNS1,SPHK2,SLC30A3,PLSCR4" Drug 7405_UP Flavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,PLA2G6,BIN1,PPFIA3,MARK4,ALDH4A1,ADGRB2,CFLAR,TAOK2,BAG4,ENTPD4,SH2B1,CRY2,FEZ1,GIT2,DNAJC6,DCT,ING4,MRNIP,RASGRP2,NCALD,ZNF589,SRCAP,GFER,RND1,GRIK2,HRH3,KCNN1,KIF5A,MBD1,MSI1,ADAM22,SLC11A2,PALM,GPR85,RAB3A,TRIM68,EPN2,SLC11A1,LIMCH1,ZCCHC24,ARHGAP26,THSD1,TCF7L2,TEX15,PARD3,PIK3R5,SSPN" Drug 6611_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADRA1D,AP1B1,MTUS1,MRTFA,BIN1,APC,CDK5R1,SYNJ2,MYRF,HOMER3,ARMC8,CPS1,CREM,NCOR2,PDE4DIP,SUGP2,AASS,PLEKHO1,LRRC23,POLL,GRK4,SYNPO,INPP5B,KPNA5,MAPT,AFDN,GIT1,LYRM9,NDP,NUMA1,FSD1,MAPK7,RAB3IL1,RAD52,SBF1,ZNF821,BCAN,SMARCD3,EMC1,SPTAN1,MAPK8IP3,EXOC7,WSCD1,GPR161,TRIO,SSBP2,ZKSCAN5,TFIP11" Drug 4822_UP Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "SYN3,ADD2,FZD9,AP2A2,ANK1,ANK2,KSR1,CAMK2B,CHRNB2,VCAN,CTH,MYEF2,KBTBD11,ATN1,DTNB,AASS,EN2,ST3GAL6,FGF1,HPCAL4,HBS1L,GPM6B,PCLO,GRIN2C,KPNA5,MMP16,ADAM22,MSR1,NCAM1,MTRF1L,PURG,MAPK7,RELN,ZSCAN32,PTPRB,RPS6KA2,ZFP2,JMJD6,ZFR2,SYT5,PCDHGA10,TEK,GPR161,THBS4,FAM155A,MKRN3,GDPD5,JPH3" Drug 3907_UP PHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADD2,ADRA1B,ANK1,CDC14B,RGS20,ASGR1,ADGRB2,SCAPER,MTMR3,CACNA1I,CAMK2B,ARHGEF1,STOML1,AKAP7,DCC,ELMO1,KLHL3,RASGRP2,MTSS1L,ERBB4,DLC1,ALDH1L1,RND1,GRIK5,ICA1,TJAP1,ITIH2,L1CAM,ADAM22,NNAT,NPTX2,SLC11A2,STRN3,LRP12,MAPK7,GRAMD1C,ZDHHC14,EPN2,SLC8A1,IZUMO4,HECW1,TBCEL,PCDHA5,TMOD1,PRDM2,STMN4,PAK5,DPF3" Drug 4754_DN PNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,MTUS1,LTBP4,MRTFA,AMPD3,FAM131A,ARRB1,MARK4,ADAM15,ST3GAL5,CACNA1D,CAMK2G,ADGRG1,QKI,AKAP12,PPP6R2,TBC1D5,MFAP3L,HSD17B14,NCALD,KAT8,BAIAP2,PDLIM5,GAD1,GLYR1,GLS,NR3C1,GRM1,ATXN2L,LIG4,LMO2,MEIS1,KITLG,PRKAR1B,PTK2,FAM120C,RAB3A,ZDHHC14,RGS3,FAM214B,ARHGAP26,NXT2,PLCB1,KAZN,DICER1,THRA,ZKSCAN5,MICAL1" Drug 6863_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ALAD,LTBP4,MRTFA,ASPH,ADGRB2,BAIAP3,CBFA2T2,TAOK2,CLU,QKI,PICK1,SH2B1,DZIP3,MFAP3L,LPAR6,PTK2B,FGFR1,FOXG1,GPM6B,LPAR4,KCNJ5,KCNN1,TAGLN3,MX1,NLE1,STRN3,FSD1,PRKAR1B,MAPK7,SYTL2,PBRM1,TRAPPC13,SBF1,ZNF821,FUZ,PEX26,BTBD7,CDK5RAP2,KDM4B,SPART,CEP68,ARHGEF12,BEX4,RBFOX2,TRIO,VAV2,LMF1,MVB12B" Drug 5725_UP Ricinine [524-40-3]; Up 200; 24.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "PLA2G6,FAM135A,TRMT9B,APC,PRX,ASTN1,ST3GAL5,RAB26,CNR1,ABCG1,FEZ1,SDC3,C2CD2L,ATN1,ING4,MRNIP,EPHB1,PIPOX,HPCAL4,TBR1,DENND2A,GPM6A,GPR22,GRM7,GRM8,HPCA,VWA5A,NDUFA5,NPTX1,OPCML,PDE4D,GPR85,PFKFB2,ZSCAN32,ZCWPW1,RFX2,RGS10,RXRA,DZIP1,PPP4R3A,SLC6A9,IQSEC2,MCF2L,TCF4,SZT2,TLR4,PRDM2,SEMA3B" Drug 3763_DN Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ASIC1,ADRA1D,APC,ARRB2,NEURL1,CHM,PLEKHB1,LHX2,NRXN3,HOMER3,CNTNAP2,CTNND2,GPRASP1,RIMS3,GIT2,MFAP3L,SGSM2,ANKMY1,PNMA2,OGA,NEU3,GFER,HSF2,IL12A,INPP5B,ITPKA,LMO2,STRN3,PPARA,CNNM2,SAMD9,PLPPR1,RAD52,BEND5,RGS10,SLC22A4,LHPP,SMG6,GPR161,CABIN1,TNS1,TRIO,XRCC4,MAP3K12,NT5M,HPS4,TIGD6,AAAS" Drug 2782_DN Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "RALGAPA1,APP,ARHGDIG,BAIAP3,ASIC3,CNOT8,SLIT2,DNAJB5,CREM,ENTPD4,CSF1,EDRF1,DAPK3,ARMCX2,JAKMIP2,RABGAP1L,DTNA,HIPK3,OPTN,ING4,NCALD,SEPT9,ALDH1L1,AHDC1,POLL,GRIK5,ELOVL5,ITIH2,ADAM22,SLC11A2,MAPK8,CNNM2,FAM120C,ZSCAN2,RAD52,C1orf54,RGS10,SMARCD3,LIMCH1,ZC3H13,SPART,INKA2,SEMA4A,TMEM121,SLC44A1,KAT6B,CABIN1,MAP3K12" Drug 6507_DN Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADCY6,MTUS1,AK2,AMH,CDC42BPA,EPB41L5,ALDH4A1,CFLAR,SYNJ2,BTRC,B4GALT6,SIPA1L1,DZIP3,PPP6R2,GIT2,DBT,MFAP3L,SMG7,EGFR,IRAK4,CDKL3,EZH1,F3,GNG4,GPR37,CNTRL,GRIK5,IL6R,LMO2,MAPT,NF1,OCRL,PIK3CD,MAPK7,CCDC25,TRAPPC13,EPN2,UNC5B,SS18,NXT2,EXOC7,PSD3,AHCYL2,KCNK12,ZBTB14,GDPD5,ST7,SSPN" Drug 6359_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "AP1B1,MTUS1,AK2,APOC1,PPFIA3,ATM,CLU,QKI,VCAN,SDC3,INTS1,GIT2,CNIH3,PLPPR4,SLC12A6,LRRC23,ANKMY1,FGFR1,PRELID3A,GPR153,INPP5K,L1CAM,MX1,FA2H,RAB3IL1,RAB5B,UEVLD,FUZ,NUBPL,SMARCC2,TMCC1,WDTC1,ZBTB43,THSD1,SS18,FCHO1,STX1A,SYN2,EXOC7,TRIM2,CHST8,TK2,SSBP2,ZKSCAN5,HIRA,UBTF,NDRG4,EMSY" Drug 4474_DN Sulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ALK,BIN1,APBB1,APC,SHROOM2,MARK4,CDK5R1,SCAPER,REPS2,LY86,ENTPD4,AATK,GIT2,PARD6A,AK5,PLEKHO1,SPEG,KIAA1109,BACH2,HNMT,MAPT,TM6SF1,NF1,PIK3R1,SLC25A23,PRKAR1B,ELOVL2,RGS10,KIRREL1,CLIP1,SUPT20H,SH3BP2,BTBD7,SLC20A2,WDTC1,UNC5B,SPTB,IQSEC2,ZBTB43,SYT1,IQCE,TEX15,TMPO,WNT7A,ZNF24,WNK1,EVI5,SEMA3B" Drug 2166_UP Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "SYN3,ADORA1,FAM135A,AMPD3,BIN1,RASL11B,SLC4A4,MPDZ,CFAP410,CACNA2D1,CDH2,CHRNA4,TAOK2,ZFYVE9,NMT2,AATK,PDE4DIP,RIMS2,PLPPR4,CDON,SIDT2,LRRC23,TUBB4A,CGREF1,ALDH1L1,RND1,GRM8,TJAP1,MAP4,MYO7A,NOVA2,NTRK2,PRKCZ,PROX1,ZCWPW1,RGS4,NEK11,SLCO1A2,SPTB,SYT1,WSCD1,SYNE1,TGFBR3,VAV2,VIPR2,VSNL1,CLIP2,GDPD5" Drug 5883_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "GAS7,SYNJ1,MYRF,HAP1,RCBTB2,CSF1R,PDE4DIP,ARHGAP24,CNIH3,TOM1,CNNM1,MBNL2,ING4,RGS17,PIPOX,DLC1,SEPT9,GNAO1,GPR37,ITIH2,KCNJ5,KPNA5,MIA2,CNOT4,PRKAR1B,MAPK7,MAPK8,RAB3IL1,PNMA8A,TMEM206,ZNF671,MAPK12,ASAP3,SLC11A1,SMARCD3,SAMSN1,COBL,ASTN2,KLHL4,PCDHA5,TMEM121,TRPC3,UGT8,LAT2,NT5M,SCG2,KCNAB1,DPF3" Drug 7186_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ASPHD1,ABHD6,AP2A2,BIN1,EP400,APAF1,BCAS1,ARHGDIG,ARRB2,CDK13,ATM,SCAPER,USP2,SRSF11,FOXN3,HOMER3,CREM,NCOR1,ABCG1,DTNA,SIDT2,SORBS3,MRNIP,IP6K2,ATP2C1,GABRA2,SEPT9,KIF5C,IPO5,NRGN,SETD4,PBX1,SLC25A23,FBXW7,AMBRA1,ELMO2,SLC20A2,ZHX3,UHRF1BP1L,UNC5B,TCF7L2,TRIM2,METTL3,RPRM,PLPPR2,VAV1,VGF,WIPF2" Drug 5592_DN troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "C1QTNF3,SEMA6A,BIN1,APBA2,APC,APOC1,ARHGDIG,PDE8B,MARK4,GYG2,CBFA2T2,CRLF1,SOCS6,FADS2,ARHGEF10,ATN1,HIPK3,COQ7,STX2,SEMA4D,CRCP,RAB30,GPM6B,RASSF8,ITIH2,MEF2C,MID1,NF1,NRGN,PLEC,PPP2R2B,MAPK8,PRODH,RPS6KA2,SBF1,SH3BP2,SLC1A7,SHANK2,MAPKBP1,PHLDB1,STX1A,WSCD1,KIAA0930,PSD3,TGFBR3,CABIN1,REEP1,PLSCR4" Drug 1887_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADORA1,PKP4,SEMA4G,ASPH,NUMB,CNOT8,CNTFR,CDC42BPB,DAPK1,RUSC2,C2CD2L,SRGAP3,DPYSL2,EFNB3,TNK2,EPB41L1,FGFR1,SCARA3,TRMO,SMC2,ATP2C1,NCKAP1,GAP43,TMEM8B,CRCP,PRRC2B,KTN1,NELL2,PAK3,TRHDE,PTPA,PRKACB,MAPK7,ACSS3,ARID4A,NUDT11,KDM4D,ARHGEF40,OBSL1,TK2,SEZ6L,TPM3,UBE3A,LMF1,WNT7A,MAP3K12,SLC17A7,MVB12B" Drug 2749_UP Monocrotaline [315-22-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "OSBPL1A,NME5,TRMT9B,PPFIA3,CDC14B,ST3GAL5,FADS2,CRMP1,CSF1R,PLCH2,SEC14L5,SPOCK2,SPOCK3,SLC12A6,SIDT2,EFNA3,DMTN,ETV1,FGFR1,FHL1,SIGLEC8,GRM2,BTN2A1,TJAP1,IL6R,KCNQ3,KIT,MAP4,MMP16,NTRK2,CDK18,PRODH,SIDT1,RFX2,RPS6KA2,EMID1,PPP1R9A,SLC2A5,PKNOX2,SOX10,IQSEC2,TROVE2,SAMSN1,PHLDB1,TRIO,EMSY,EPM2A,NLRP3" Drug 282_UP fludrocortisone acetate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "RALGAPA1,ABR,RBM10,ASCL1,ATP2B2,CAMK2B,ADGRG1,TAOK2,COL4A5,AATK,ECE2,C2CD2L,SMG7,RCAN1,MBNL2,LPAR6,ELAVL4,FGFR1,SEC23B,RUNDC3A,GLYR1,NCKAP1L,NAP1L1,NF1,NPR2,OPCML,OPRL1,PLCD1,PLEC,RAB3IL1,C1orf54,SEMA6D,SH3BP2,ST6GAL1,SLC9A5,WDTC1,LMO3,NXT2,PHLDB1,PRRC2C,COBL,SZT2,CHST8,UBE3A,GDPD5,SNX27,MPPE1,ZNF248" Drug 2902_DN Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "AP2A2,ARNTL,CDK13,NUMB,CFLAR,CDC27,HOMER3,CSF3R,ARHGEF10,PPP1R16B,ARHGAP32,TBC1D5,DTNA,ABCC5,FHL1,ERAP1,RAB40B,MUM1,IL6R,JAK2,MX1,NUMA1,OPA1,PIK3CD,PIK3R1,PTPA,SNRK,TMEM231,ROGDI,DGLUCY,MAPK12,ZFP30,SH3BP2,PPM1E,ARFGAP1,TSPYL2,SS18,NSFL1C,DNMBP,PDLIM2,ZEB1,TMPO,ZNF24,ZNF225,NT5M,CIAPIN1,FIP1L1,MARCH8" Drug 308_DN sulindac sulfide; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADORA3,MTUS1,C1QTNF1,ALCAM,BEGAIN,OGT,APAF1,APBB2,APP,AQP6,ATP6V0A1,SYNJ2,INA,CHGB,CNTN1,TBC1D5,TMCC2,DLG3,ABCC9,ERBB4,ETV1,EXTL2,KIAA1109,GAP43,MAN1B1,ITIH2,AFF1,ADAM22,NEUROD2,NF1,NOVA1,ODF2,PRKCB,MAPK3,PRPH,MTMR10,RALGDS,PBRM1,RNASEL,ZNF821,SH3BP2,KBTBD4,SNAP25,SNCA,HECW1,VPS13A,TRPM2,ZNF195" Drug 3540_UP Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,SLC12A5,ANK2,APBB2,SLC4A4,CFLAR,CACNB2,DGKI,CDH2,SLIT2,FADS2,ENTPD4,CSF1R,RIMS2,DBT,EDNRA,PLXNC1,SORBS3,KCNMB2,SPEG,GATM,MALT1,RND1,GNG4,GPD2,GRM8,PTGDR2,KCND3,ADAM22,PENK,LRP12,CCDC40,RAD52,FAM184A,RGS12,KCTD17,NEK11,SH3BP2,SLC6A9,ARHGEF40,PCDHGA10,TNS2,CRTC1,R3HDM1,PLPPR2,VAV2,NT5M,SLC17A7" Drug 7386_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MRTFA,CFLAR,MYRF,ARHGEF2,CHM,IQCK,BAG4,ENTPD4,PPP6R2,KIAA0513,DLG3,CDON,FEM1B,EN2,SPEG,ATP2C1,DENND2A,COPS8,GLRB,GNAS,GPER1,INPP5B,LIG4,NUCB1,BCAS3,RAD51D,RGS10,MCMBP,TMEM156,SBF1,SCN8A,FAM214B,KDM4D,KBTBD4,BTBD7,LIMCH1,ARHGAP26,ZBTB43,ELOVL4,CEP68,VAMP1,KIAA0930,SYNE1,NSD1,TIAM1,BHLHB9,UPF3A,MAP3K12" Drug 1695_UP Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "AP2A2,C1QTNF3,ALCAM,ATP6V0A1,CFAP410,CBFA2T2,ARHGAP33,TAOK2,ZFYVE9,PDE4DIP,GREB1,DCAF8,GIT2,TMCC2,DNM2,DTNA,EIF4G2,LRRC23,SEMA4D,C1QL1,PRUNE2,TDRKH,TJAP1,IL6ST,ITIH2,MAP4,NUMA1,ODF2,RETREG1,PLXNB1,PMP22,CARF,EMID1,SMTN,SLN,ZCCHC24,NMNAT2,ZBTB43,TROVE2,ST5,EXOC7,TCF7L2,TRIM2,PSD3,KAT6B,TRPC1,VIPR2,EPM2A" Drug 2998_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,ANK3,MAP4K3,CAPN3,CLCN4,ARMC8,CSNK1E,SIPA1L1,PPP1R16B,ZNF337,FRY,FAM13A,PLXNC1,LRRC23,VPS26C,EFCAB2,CAMKK2,SEPT9,GART,NCKAP1L,INPP1,ITGAM,KCND3,MAP4,NEFH,NRGN,NUMA1,PDE4B,PLTP,MBOAT7,PTK2,PTN,CEP97,RALGDS,KHDRBS2,CCDC25,UEVLD,DGLUCY,FOXRED2,BTBD7,SLC20A2,TROVE2,SS18,FAM168A,ATP11A,SZT2,TPD52,MPPE1" Drug 2765_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MRTFA,APP,CDC14B,ASPH,NCOA1,ATP6V0A1,RIPK1,CBFA2T2,SCARB1,CNOT8,FAM189A2,CREM,PDE4DIP,PPP6R2,TRAPPC9,GNE,IRAK4,F3,ZNF589,FGFR1,DISC1,GLYR1,RAB30,GLS,CACFD1,KCNH2,LSS,MITF,ZNF862,NEK1,NLE1,RGS10,RNASEL,PPM1E,EPN2,EMC1,UNC5B,MAPK8IP3,STX1A,VPS13A,TMOD1,TRPC1,CLDND1,ZNF24,TFIP11,EVI5,MPPE1,PHTF2" Drug 2457_DN Hexetidine [141-94-6]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "BRAP,SRPX,AMPH,APBB2,APOC1,ATP2A2,SCAPER,CFAP410,CDC42,CHRNB2,TPP1,SLC4A7,ARHGEF10,CX3CR1,DGKG,NR1D2,DTNA,FEM1B,EFNA3,PLEKHA1,TNK2,C3orf18,RASGRP2,NCALD,MAP4,MDM4,SCAMP5,MYO7A,NF1,NUMA1,PMP22,PRKAR1B,MAPK8,MAPK10,RAD52,ZNF493,RGS10,EMID1,SMTN,SLC11A1,IQSEC2,ZC4H2,ADGRL3,TNS2,CRTC1,KCTD2,LAMP5,ZNF225" Drug 5461_DN Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "C1QTNF3,CDC42BPA,DNAH17,BRINP2,ATM,CFLAR,BAIAP3,CCNT1,ARHGAP33,MAGI1,SRSF11,PICK1,EDRF1,DAPK3,MFAP3L,RUSC2,DSCAM,VPS13B,F5,FHL1,EFCAB2,GCNT2,GPM6B,TDRKH,GRIK5,AP4S1,KCNF1,MAP4,ADAM22,CNOT4,RETREG1,LRP12,MAPK7,PRODH,PTHLH,ELOVL2,ZDHHC14,GSTCD,ZNF821,CXXC4,EMC1,MAPK8IP3,AJAP1,SEMA4A,RPGRIP1L,SPHK2,WNK1,SENP7" Drug 1726_UP Thiocolchicoside [602-41-5]; Up 200; 7uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "BIN1,APBA2,ARNTL,RASL11B,CFLAR,OSGIN2,CD86,ZFYVE9,SEC31B,PPP1R16B,DOCK4,G3BP2,TRAPPC9,DPH1,SIDT2,EFNB3,ING4,ECSIT,KAT8,KIAA1109,TRMO,SRCAP,NR3C1,FAM107A,MUM1,NXPH3,ACOT7,GIT1,MYT1,NINJ2,ODF2,OPA1,PLEC,RGS3,RIC8B,SATB1,ATXN2,ZCCHC24,VAMP1,KCTD2,PARD3,KAT6B,ZMYND8,SSBP2,NPDC1,WNK1,JMJD1C,AAAS" Drug 6960_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,AK2,ATM,RIPK1,SRSF11,ARMC8,CHD1L,CREM,ABCG1,DAPK3,DBT,FBXL5,MED24,FCF1,POLR1B,FHL1,EFCAB2,CINP,CNTRL,KCNF1,KCNJ3,MAP4,LYRM9,NPR2,PMS2,SAMD9,ELOVL2,PEX5,RAB3A,RAD51D,SAFB,SH3BP2,SYBU,ABLIM3,ZKSCAN3,EMC1,LHPP,FCHO1,ARC,SYT1,ANKRD12,EXOC7,TCF7,TCF7L2,METTL3,VGF,VIPR2,NUP214" Drug 3126_DN Gliquidone [33342-05-1]; Down 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "MRTFA,BIN1,AMT,CDK10,ASPH,ATP6V0A1,MTMR3,BTRC,SCARB1,SOCS6,AKAP7,ARMC8,DGKG,SPOCK2,RHOBTB1,DNM2,VPS13B,FGFR1,GAA,ADAM28,GPD2,PCLO,GRM1,IRF8,KIT,MAP4,NRCAM,P2RY1,PFKFB4,PPP3CC,CNTLN,SBF1,SEC14L1,RASA3,TMCC1,TNIK,ZCCHC24,SPTAN1,IQSEC2,FAM168A,DNMBP,SIN3B,PCDHGA10,TPM2,FLRT2,PLPPR2,ZBTB14,TIGD6" Drug 5627_UP Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADD2,ADORA3,PLA2G6,ALK,SYT13,CDC42BPA,KSR1,BAIAP3,CCKBR,CACNA2D2,PICK1,VCAN,NOS1AP,SMG7,ELAVL2,CEND1,PRUNE2,KHK,VWA5A,MAN2A2,MAOB,MARK1,MOBP,SLCO1C1,NPY,TREM2,PFKFB2,CEP41,PRKCB,MAPK10,PTAFR,CCDC40,RORB,KCNIP1,SH3GL3,CNKSR2,SLC1A7,SLC11A1,SLCO1A2,KIF13A,KIF21B,MAPK8IP3,SYN2,EXOC7,WSCD1,SEZ6L,KCNAB1,SLC17A6" Drug 335_DN nifedipine; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADCY6,DGKD,ATM,MTMR2,ARHGAP33,CRHBP,ARHGEF10,PDE4DIP,INTS1,CALCRL,EFS,CEND1,FHL1,FOLR2,KHDRBS3,MPP6,TMEM8B,NEU3,LILRA2,GPR19,GRIN2C,BTN2A1,ARHGAP19,HLF,HMX1,IGF1,KHK,MAPT,MBOAT7,MAPK8,CRTAC1,SATB1,SH3BP2,FERMT1,PPP4R3A,SLC9A5,IGSF9B,KDM4B,SPART,SSTR2,TRIM2,CDH22,SEZ6L,ZMYND8,TUBB1,WNT7A,SLC13A3,MPPE1" Drug 7194_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,ADD3,AK2,BIN1,APAF1,APBB2,EPB41L5,CDK10,ST3GAL5,SCAPER,USP2,PICK1,SMARCAL1,CREM,MICAL2,DZIP3,TBC1D5,C2CD2L,TOM1,FEM1B,PHF20L1,ZNF589,AFF2,FYN,GLYR1,MSL3,NF1,NRCAM,PDPK1,PRKAR1B,TMEM104,PEX5,RAB3A,NEK11,SMTN,TROVE2,ARHGEF9,EXOC7,TCF7,TCF7L2,TNS2,PCDHA5,KCTD2,PARD3,CABIN1,LMF1,REEP1,MAP3K12" Drug 1751_UP Stachydrine hydrochloride; Up 200; 22.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ASIC1,ARID1A,NDRG2,BEGAIN,PPFIA1,APP,SEMA4G,ADAM15,SCAPER,LDLRAD4,ZFYVE9,PICK1,CNTFR,ECE2,ARHGAP32,DBN1,KLHL3,DNM2,FEM1B,ECSIT,EFCAB2,POMT1,SRCAP,GRB10,ELOVL5,ACOT7,PLCB2,PTPA,RAD51D,RAP1GAP,RGS12,SEC61A2,TMEM206,LGR4,BCAN,LIMS2,KBTBD4,THSD1,FAM168A,TAC3,TBL1X,THBS4,TNS1,SMUG1,SSBP2,VGF,LAMP5,HPS4" Drug 7352_DN Zalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG3,APC,CDC14B,ARHGAP5,MARK4,ATP6V0A1,ADAM15,CFLAR,C5,CA12,KYAT1,ARHGEF1,MAGI1,TAOK2,PLAA,SLC4A7,RCHY1,CSNK1E,SDC3,RIMS2,HP1BP3,DRD1,EFNA3,DMTN,LRRC23,PRKAG2,SEMA4D,GART,GPD2,RNFT2,HNMT,ITPKB,MITF,MMP16,SLC11A2,MAPK8,SYTL2,WDR25,BTBD7,ZKSCAN3,CLASP2,AHCYL2,BEX4,XRCC4,REEP1,DNALI1,SMIM8,ACTR3B" Drug 1333_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "OSBPL1A,PPFIA4,APAF1,GAS7,LDLRAD4,FOXN3,DZIP3,ARHGAP32,TBC1D5,ERCC2,TRMO,CINP,CELF1,CGREF1,BTN2A1,MAP4K5,ICA1,TJAP1,IL6R,INPP1,NF1,CNOT4,RETREG1,MINDY2,PPP3CB,MAPK3,PTK2,RGS10,ARHGEF10L,PAQR6,RXRA,FAM102A,FNDC3A,ARHGEF40,SLC22A4,TSPYL2,TROVE2,POGZ,ARHGEF9,EXOC7,TNS1,TRPS1,VIPR2,NPDC1,EMSY,FIP1L1,MPPE1,PHTF2" Drug 6585_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "RBM10,ADCY6,BIN1,ANK3,APC,GAS7,ADAM23,BID,DNAJB5,HOMER3,CHD1L,ENTPD4,ABCG1,SIPA1L1,DCAF8,MAML1,DAPK3,GIT2,DMPK,DUSP9,APH1A,SORBS3,STX2,FGF1,INPP5K,GFER,NR3C1,SLC2A6,DHX35,KCNMA1,LYRM9,ZNF862,PLCD1,ARHGEF10L,WDR47,FAM214B,RAB3GAP1,BTBD7,COA1,CDK5RAP2,ZBTB43,EXOC7,TNS1,XRCC4,REEP1,SEMA3B,NAV3,MPPE1" Drug 662_DN resveratrol; Down 200; 50uM; PC3; HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ADORA1,PRX,PDE8B,BCL7A,CA4,NEURL1,CDC27,FOXN3,KIAA1549L,FEZ2,ZNF337,RHOBTB1,DTNA,RBM12,KCTD3,TNK2,EPB41L1,EPB41L2,OLFM1,CAMSAP1,NCKAP1,MALT1,RUNDC3A,DBF4,GLI2,GNG4,HAS2,PTGDR2,ARHGAP19,NCF2,NPY,PDE1C,SMIM7,ATG16L1,RGS3,RGS4,NUDT11,ZNF821,SFPQ,SLC11A1,DIP2A,JMJD6,TBL1X,WSCD1,SZT2,ARHGEF12,KCTD2,ZFAND5" Drug 4469_DN Stachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "RALGAPA1,NME5,PLA2G6,BIN1,MTMR9,CFLAR,HIP1R,MAP7,OSBPL3,SIRPA,AK5,EDIL3,CNNM1,FAM13A,IRAK4,DENND2A,SEPT9,KPNA5,MBD1,MPP2,MX1,CNNM2,SAMD9,SNRK,RAB5B,TTLL7,CLIP1,IL17RB,ASAP3,KDM4D,SHANK2,SLC20A2,WDTC1,KDM4C,SPTAN1,SPTB,ZBTB43,COLGALT2,DIP2A,COBL,SYNE1,ARHGEF12,CRTC1,ATP13A2,TMPO,CABIN1,TNS1,ZKSCAN5" Drug 6181_DN 2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG3,AGT,APOC1,CASK,NCOA1,BMP7,CAPN3,HIP1R,CD86,SCARB1,SOCS6,RAB33A,ZFYVE9,NMT2,CPS1,C2CD2,OSBPL3,PPP1R16B,SIDT2,RASGRP2,CD320,CAMSAP1,INPP5K,SLC2A6,MUM1,ATXN2L,TJAP1,SMAD1,MAPK8,PTAFR,PTK2,RIPOR1,RET,SEC14L1,MRAS,ARFGAP1,KAZN,DNMBP,TCF7L2,PSD3,TGFBR3,THBS4,KCTD2,KAT6B,TNNT1,TNS1,PLPPR2,ACTR3B" Drug 4476_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "AMT,OGT,CDC42BPA,APBB2,CFLAR,C5,KRIT1,SCARB1,CNOT8,LY86,CNTNAP2,ZNF337,TBC1D5,DBT,RABGAP1L,DTNA,HSD17B14,ETV1,ATP2C1,ZMYND11,SPIN1,FERMT2,KIF5C,ARHGAP12,MX1,NFYA,NUMA1,PCDH9,PDE1C,CDK14,FSD1,MED1,SNRK,PTCH1,SLC25A36,MAP6D1,ASAP3,SLC20A2,EMC1,KDM4C,SS18,SYT1,COBL,PSD3,CADM1,SF1,WNK1,PRDM2" Drug 6897_DN NS-398; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,AP2A2,BIN1,CDC42BPA,FAM131A,ARRB1,BTRC,CAMK2B,CLGN,CRLF1,STOML1,LRIG1,DBN1,FBXL5,TRAPPC9,EPB41L1,DMTN,STX2,FGFR1,GPR153,USP19,GLYR1,GPR19,NR3C1,HSD17B1,KCNF1,MAP4,NEK1,PLCD1,MINDY2,MAPK7,PTAFR,C1orf54,ZDHHC14,SH3BP2,FRMPD1,PREX2,SHANK2,LIMCH1,ARHGAP26,IQSEC2,SUPT5H,ATP11A,KAZN,TRIM2,TK2,MICAL1,ZBTB14" Drug 3849_DN Acacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "NDRG2,ADRA1D,MRTFA,APP,ARRB1,ALDH4A1,ATP6V0A1,BAIAP3,CALB2,HAP1,CAMK2B,CBFA2T2,CHM,TAOK2,BAG4,ARHGEF10,DAPK3,GIT2,DTNA,MBNL2,CDKL3,GLS,PCLO,IL6ST,NPR2,PCDH9,RETREG1,PLCD1,STRN3,MINDY2,PPP5C,CNNM2,SNRK,ZSCAN32,RGS10,RGS12,SLC15A2,BTBD7,ZCCHC24,VAMP1,SYN2,ARHGEF12,TGFBR3,TMOD1,RUNDC3B,ZFP37,KCNAB1,SSPN" Drug 5643_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ABHD6,TRMT9B,BIN1,AMT,MARK4,ATP2A2,GYG2,CACNA1I,CBFA2T2,ARHGEF2,UBE2L6,RCBTB2,CHRNB2,STOML1,FAM189A2,NRG2,SH2B1,TMCC2,VPS13B,IGSF6,ATP8A1,ZNF589,FGF12,BAIAP2,SRCAP,GLS,ITIH2,KCNMA1,KIF2A,MSI1,ADAM22,PDE3B,PPP3CC,PRKAR1B,FAM184A,ZDHHC14,BCAN,FAM214B,COA1,ATP11A,ROBO3,DMXL2,TGFBR3,CABIN1,PLPPR2,ZNF711,EVI5,SENP7" Drug 2172_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "PLA2G6,KCNAB2,ZBTB10,SYNJ2,CCNT1,LARGE1,NMT2,CST3,TM9SF4,DGKG,SIDT2,ING4,EIF1,RASGRP2,F5,FHL1,GATM,POLL,GPR22,PADI2,KPNA5,MAP4,MDM4,SCAMP5,MYT1,NUMA1,DEF8,TMEM104,PTAFR,RAB3IL1,RAD52,RNASEL,SBF1,SLC20A2,ZHX3,RBM26,DDN,ATP11A,EXOC7,PCDHGA10,PSD3,ZNF34,THRA,R3HDM1,KAT6B,ZMYND8,PRDM2,UBE3B" Drug 4948_DN Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "DOC2A,PPFIA3,APP,ASPH,BTRC,CLU,RAB26,ENTPD4,EDRF1,JAKMIP2,MFAP3L,MED24,SMG7,TRAPPC9,RCAN1,TSPAN5,EDNRA,PLEKHO1,ACSL4,FGF12,PRELID3A,POLL,DHX35,IGSF1,KCNJ3,VWA5A,MAPT,NF1,NPR2,PDE3B,PLCD1,PLEC,POLG,WDR25,ZCWPW1,FBXW7,SBF1,SH3BP2,PPP1R9A,EPN2,SMTN,SS18,FCHO1,NSD1,ATP13A2,TMOD1,KCTD2,VAV2" Drug 6125_DN Leucomisine [17946-87-1]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "ASIC1,N4BP2L1,BACH1,SGCE,CHM,SH2B1,CSF1,PPP1R16B,SGSM2,RABGAP1L,ABI2,ENO2,ZNF589,ANKFY1,ERAP1,INPP5K,WASF3,ZNF276,GLYR1,GLS,LILRA2,NR3C1,IL6ST,LIG4,VWA5A,MDM4,MIA2,NUMA1,PDE4D,CCSER2,RETREG1,STRN3,PILRA,PTPRO,MRPS18A,ZNF821,SUPT20H,FAM214B,SLC11A1,WDTC1,FBXW11,TCF7,KCTD2,PARD3,RBFOX2,KCNAB1,UBE3B,PHTF2" Drug 3394_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-03 1.00E+00 7.27E-03 8.28E-02 48 197 "AMPD3,BIN1,CNTNAP1,APC,APLP1,PLA2G4C,DNAH17,SCAPER,CACNB2,CCNT1,CLGN,STOML1,PICK1,CTH,RIMS3,SLC12A6,DSCAM,NCALD,SPEG,FGF12,OGA,RUNDC3A,RAB30,KCNJ5,KPNA5,SMAD1,MAPT,GIT1,MSI1,NDUFA5,NF1,SNTG1,CDK14,PLTP,MED1,RGS10,PEX26,PKNOX2,SMARCD3,ZCCHC24,TSNAXIP1,DOK5,VAMP1,TCF7L2,PDIA2,WIPF1,SPHK2,EVI5" Drug CID000003987 oleoyl-lysophosphatidic acid Stitch 1.04E-03 1.00E+00 7.29E-03 8.29E-02 85 392 "ABHD6,ADRA1B,OSBPL8,PLA2G6,SEMA6A,MYH7B,GPAM,ARRB1,ARHGEF25,CDC42,CHN1,MYL6B,CLTC,AKAP5,AKAP12,RGS6,CTNND1,ZBTB24,DPYSL2,DNM1L,SH3GLB1,EGFR,BSCL2,ENPP6,ERBB4,PTK2B,FGF1,ACTL6B,WDR83,GAB1,MSTN,MALT1,RND1,GNAL,GNAO1,GNAS,GNG3,GOLGB1,GPR12,LPAR4,MCHR1,GRB10,GPR45,IGF1,SCIN,GIT1,MYL3,NODAL,NPR2,KCNK10,ENPP2,SSH1,PIK3C2A,PIK3CD,PIK3R1,MBOAT7,PRKCB,PRKCG,MAPK3,MAPK4,MAPK9,MAPK10,ELOVL2,PTK2,RASGRF1,RDX,RET,RGS3,RTKN,MAPK12,SLC6A1,SLC20A2,PALLD,TBL1X,TIAM1,ACTR6,DDHD1,TRPC1,TSC1,GORASP1,P2RY12,SLC26A10,SPHK2,PLPPR5,PLD4" Drug CID000066393 "estradiol-2,3-quinone" Stitch 1.04E-03 1.00E+00 7.32E-03 8.33E-02 25 85 "SLC25A25,ADRB2,AQP4,ARSE,CCK,FEM1B,AGAP3,GFAP,GRIA1,GRIA2,GRIA4,MAP4K5,HNMT,HTR2A,NPY,PDE1A,PDYN,PENK,POU3F2,SOX11,SST,TAC1,TNR,TRH,SLC17A7" Drug CID000008343 DEHP Stitch 1.04E-03 1.00E+00 7.32E-03 8.33E-02 25 85 "LRRC4C,USP6,CDO1,CP,DLG4,DMPK,DYRK1A,EGFR,ERBB4,CACNG2,POLK,PPARGC1A,BRD8,GRIA1,GRIA2,GRIA4,CIT,KCNJ16,NOS1,PENK,ABCB1,PPARA,MAPK3,DDN,TP53BP2" Drug 6144_UP Piretanide [55837-27-9]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ACTN2,ADORA3,BCAR3,BIN1,APBB2,ARSE,BTRC,CA12,RUNX1T1,SEPT7,CHRNA4,PICK1,ABCG1,RIPOR2,DGKG,SPOCK2,DMD,TRAPPC9,EFNA3,SORBS3,ING4,ERBB4,ARMCX1,FOXG1,KHDRBS3,ZMYND11,GRM8,SCIN,NHLH1,P2RY1,PRPH,CNNM2,MYH14,CARF,FBXW7,SLC1A7,SHANK2,SLC20A2,TMCC1,KDM4B,RALYL,SLC35G2,TK2,TMOD1,BEST1,MKRN3,ZBTB16" Drug 3858_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ADRA1D,LTBP4,AMH,APC,FAM131A,BMP7,CFAP410,C2CD2,ARHGEF4,RIMS2,KBTBD11,RASGRP1,EGR3,ELN,FGFR1,ALDH1L1,GFER,MSL3,POLL,ATXN2L,NPR2,PFKFB3,PLCD1,PPP5C,MAPK7,SIDT1,PTPRE,ENOX1,ZMAT4,RET,RGS10,EMID1,SH3BP2,ASAP3,ZNF365,SLC1A7,FAM214B,LIMCH1,KIF13A,MCF2L,CHST8,TIAM1,TK2,VIPR2,LAT2,GDPD5,NAV2" Drug 2919_DN Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "NDRG3,BRAP,ADRB2,MRTFA,PPFIA4,ZBTB10,ATP2B1,CFLAR,SCAPER,KRIT1,SLC16A4,ZMYM4,CHM,QKI,CPS1,ENO2,F3,ZNF589,FGFR1,SEMA4D,FLT1,POMT1,ATP2C1,SESN1,MAN1B1,IL6R,JAK2,LSS,OLR1,PIK3C2A,MINDY2,PKN2,RAD52,TMEM156,SEC14L1,SLC6A8,KDM4B,SPTAN1,JMJD6,VAMP1,ANKRD12,DNMBP,TCF7L2,TPM2,UBE3A,XRCC4,MAP3K12" Drug 7556_UP vinblastine sulfate; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ACTN1,BRAP,MRTFA,BIN1,PKP4,NUMB,CCNT1,PLAA,CLCN3,CREM,AKAP12,TOX,SGSM2,TNK2,EZH1,FGF1,AMOTL2,DPYSL4,SRCAP,FERMT2,PSRC1,PRRC2B,ARHGAP19,IL6ST,DIPK1A,KIF5C,SETD4,OGG1,PDE1C,PDE4A,MBOAT7,SAFB,ASAP3,ARFGAP1,BEX1,SRPK2,CLASP2,CAMTA2,PHLDB1,COBL,TMPO,CABIN1,HIRA,UBE3A,SYNC,PRDM2,LAS1L" Drug 6752_DN Pipemidic acid [51940-44-4]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "APC,ARHGDIG,ASPH,STX16,ATP2A2,MTMR2,CANX,CCNT1,ARHGEF1,CHM,QKI,HAPLN1,DZIP3,TBC1D5,HP1BP3,EXOG,FCF1,MTSS1L,KIAA1109,ANKFY1,FYB1,USP19,MSL3,NUDT21,SCIN,KCNN1,KIF2A,MYO6,PLCD1,POLR2F,BCAS3,CNTLN,PTK2,RAB3IL1,ZCWPW1,RGS10,TAB2,SS18,PHLDB1,GPR161,BEX4,UGT8,OSBP2,NSD2,WNT7A,KCNAB1,PHTF2" Drug 4094_DN Decamethonium bromide [541-22-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "GRAMD1B,MTUS1,AMT,CDC42BPA,KCNAB2,AQP4,NCOA1,ST3GAL5,MYRF,IL33,CFAP410,KYAT1,SCARB1,SOCS6,NMT2,TCEAL2,CRMP1,BRINP1,RUSC2,SGSM2,ING4,EML1,LRRC23,MTSS1L,STX2,SPEG,SCML2,FOXG1,CINP,SEPT9,LMO2,TM6SF1,CDK14,RETREG1,MAPK7,PRPH,PTPRB,MAPK12,CSRNP3,DZIP1,PREX2,SLN,TK2,R3HDM1,HIRA,WIPF1,SH3GLB2" Drug 2722_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ADRA1D,APC,ARRB1,NUMB,STX16,N4BP2L1,CACNA1A,CAST,CHM,RAB28,CSNK1G3,VCAN,PPP1R16B,DTNA,CELSR3,MRNIP,EPB41L2,LRRC23,OGA,FYB1,HBS1L,SEPT9,ARFIP1,LILRA2,PADI2,ITGAM,LIG4,LSS,AFF1,ZNF862,OLR1,ENPP2,MINDY2,PRKCZ,MAPK7,SNRK,RNASEL,UEVLD,FUZ,PEX26,SS18,NXT2,TCF7L2,ZEB1,TMPO,RBFOX2,WIPF1" Drug 3123_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "GRAMD1B,MTUS1,BIN1,CBFA2T2,SCARB1,ENTPD6,HOMER3,SEC31B,CSNK1E,CTNND1,TM9SF4,INTS1,SPATA2,PCOLCE2,COQ7,PTK2B,CAMSAP1,CGREF1,SEPT9,AHDC1,COPS8,SLC2A6,NRCAM,NLE1,PLCD1,PLEC,PILRA,GON4L,TMEM231,RAB3IL1,RET,ARFGAP1,EMC1,NCDN,VPS13A,KAZN,EXOC7,TCF4,TCF7,KCTD2,R3HDM1,CABIN1,TPD52,ZKSCAN5,BEST1,UPF3A,MARCH8" Drug 1778_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "RBM10,PLA2G6,APP,ARNTL,ATP2A2,ATP2B1,CAST,IPCEF1,GAPVD1,ZFYVE16,MATR3,GIT2,DBT,KIAA0753,ABI2,EIF5,COPS4,DENND4A,ACSL4,GLS,GLUL,PRRC2B,KTN1,MBD1,NEK1,NUMA1,SMIM7,ZNF426,MAPKAP1,RAB5B,PLEKHB2,RDX,UBR7,PCMTD2,ATXN2,CHD9,PPP4R3A,ARHGEF40,KBTBD4,NXT2,TTBK2,ANKRD12,EXOC7,DICER1,TPD52,EVI5,MPPE1" Drug 2785_DN Rescinnamin [24815-24-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "APBB2,APOC1,ARHGDIG,BMP7,SYNJ1,CAMK2G,SOCS6,ZFYVE9,CLCN3,HOMER3,NCOR1,SOCS5,PDE4DIP,G3BP2,EFNA3,KAT8,ZMYND11,GLYR1,RAB30,GPD2,GPR37,MUM1,HSF2,JAK2,MAP4,MBNL1,KITLG,NRGN,PDE3B,LRP12,PRKAR1B,PEX5,CEP97,RAD51D,RET,SEC61A2,IL17RB,SFPQ,SGK1,ITSN1,PPP4R3A,DMXL2,TNS2,TMPO,PARD3,UBTF,PHTF2" Drug 2699_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "MTUS1,AMT,ANK2,SLC4A4,KIF1A,CAMK2G,HIP1R,CBS,CLGN,PLAA,HOMER3,NCOR2,CTH,NR1D2,DTNA,MBNL2,RASGRP2,ZNF589,ZNF276,GNAS,GRB10,PADI2,ATXN2L,KCND3,LSS,MAP4,PTPRO,RIPOR1,FAM184A,LGR4,FOXRED2,IZUMO4,DDN,MAPK8IP3,KAZN,ROBO3,EXOC7,CAMSAP2,TCF4,TNS1,CDK20,SMUG1,FLRT2,VIPR2,MAP3K12,EMSY,HPS4" Drug 464_DN WY-14643; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "RBM10,ARID1A,AP2A2,ASCL1,ASPH,ADAM23,MYRF,CHN2,WHRN,CPS1,ENTPD4,GIT2,HP1BP3,RCAN1,SUGP2,EGFR,BSCL2,C3orf18,FCGRT,NEU3,GPER1,GPR37,CACFD1,KIFC3,NPTX1,PCDH9,SNX10,EPN1,ZSCAN32,PTX3,SAFB,ATXN2,ZNF821,ITSN1,AMBRA1,SHANK2,TNIK,SPTB,ITPRID2,MAPK8IP3,PHLDB1,GPR161,THBS4,LMF1,ZNF189,MPPE1,AAAS" Drug 3375_DN Ethaverine hydrochloride [985-13-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ASIC1,AP2A2,APBB2,APLP1,PLA2G4C,CACNA1D,HAP1,STOML1,GREB1,NOS1AP,RIMS3,DMPK,ATN1,DTNA,EGFR,ING4,CDKL3,OGA,ERAP1,SEPT9,GLYR1,GPR37,ELOVL5,ICA1,IL6R,IL6ST,ZNF862,PCDH9,STRN3,LRP12,POLG,PRKAR1B,MAPK10,PTPRO,ZFHX4,FBXW7,TCP11L1,FERMT1,PEX26,SNCA,NCDN,ATP11A,TBCEL,ZKSCAN5,VAV2,VGF,WIPF1" Drug 6809_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "ADRA1D,AK2,ALCAM,APOC1,ARRB1,ALDH4A1,ATM,ATP6V0A1,CFLAR,BTRC,CARS,PLEKHB1,TAOK2,SH2B1,SIPA1L1,SDC3,GREB1,RIMS2,PPP6R2,HP1BP3,DTNA,EFNA3,EIF4G2,ZNF589,FER,FGFR1,DPYSL4,FAM49B,OGA,FYN,INPP5K,TXNL4A,NCAM2,RETREG1,SEC14L1,SLC1A7,ZKSCAN3,EMC1,ZBTB43,CLASP2,TROVE2,KCTD2,TRIO,MPPE1,EPM2A,ST7,PHTF2" Drug 5456_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.32E-03 8.33E-02 47 192 "C1QTNF3,APBB2,CDC14B,PDE8B,ATM,BAIAP3,BTRC,CBFA2T2,CLGN,PLEKHB1,PLAA,ANKMY1,F3,FER,HBS1L,DISC1,INPP5K,COPS8,GPER1,CNTRL,MATK,ADAM22,ZNF862,NF1,CNOT4,PLEC,MAPK8,EMID1,SBF1,ZNF821,SLC20A2,LIMCH1,SPART,INKA2,MAPK8IP3,EXOC7,TCF7,AHCYL2,SLC44A1,TPD52,REEP1,ZNF189,WNK1,GDPD5,SEMA3B,EPM2A,SENP7" Drug CID005478935 Lopac-P-178 Stitch 1.05E-03 1.00E+00 7.33E-03 8.34E-02 21 67 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,P2RX6,ENTPD2,PLCXD3,B3GAT1,PLCD4,NOS1,P2RX7,P2RY1,PLCB2,PLCD1,EXOSC10,SLCO1A2,PLCB1,TAC1,TACR1,P2RY12" Drug 5958_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 7.37E-03 8.39E-02 46 187 "C1QTNF1,PPP4R4,MPDZ,SYNJ1,EPS15L1,PLAA,CLCN4,CLU,TPP1,CTH,SPOCK3,AK5,DPH1,EDN1,HEYL,FGF1,PDLIM5,RUNDC3A,ICA1,IL12A,MARK1,ADAM22,NAP1L2,NF1,OXTR,PDE1C,PDE4D,NLE1,POLG,CEP41,PTHLH,FAM120C,RAP1GAP,RGS7,RGS10,GSTCD,ZNF821,HSPA4L,PDZD2,KDM4C,ARHGAP26,ZBTB43,ATP11A,ZEB1,PCDHGB6,MPPE1" Drug 3240_UP GBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.05E-03 1.00E+00 7.37E-03 8.39E-02 46 187 "SPARCL1,SEMA6A,BTRC,SLC16A4,CD86,WHRN,NRG2,VCAN,RIMS2,EDN1,EGR3,EN2,CDKL3,FAM198B,FGFR1,HPCAL4,SORBS1,PRELID3A,ZNF44,SIGLEC8,ALDH1L1,GCNT2,GPR162,RND1,GNG3,GRIK2,ADAMTS13,GRM1,KCNMA1,KPNA5,MAP2,NF1,NTRK2,ENPP2,PHKG1,LRP12,KHDRBS2,KCTD17,SFPQ,SLC22A4,EPB41L3,ARC,DMXL2,PSD3,FAM155A,MKRN3" Drug 3851_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.05E-03 1.00E+00 7.37E-03 8.39E-02 46 187 "KRIT1,SMARCAL1,ZBTB24,RHOBTB1,SACS,ANKRD46,RBM12,EGR3,PLEKHO1,ARMCX1,TBC1D16,GPR19,RNFT2,BRINP3,JAK2,MEIS1,THYN1,PDCD2,PIK3R1,RETREG1,ZSCAN32,ERI2,ROBO1,TCP11L1,ZFP30,ITSN1,PAAF1,TMCC1,CLUAP1,ZNF302,CEP68,KANK1,ZC3H4,ARHGEF9,ASTN2,MCF2L,FAM208A,TBL1X,SMUG1,ZMYND8,ZIC1,ZNF23,HPS4,MPPE1,SMIM8,ZNF248" Drug CID000123795 Deltorphin Ii Stitch 1.06E-03 1.00E+00 7.39E-03 8.41E-02 18 54 "RGS20,CCK,BOC,SIRPA,HEYL,RGS17,DMTN,TUBB3,KCNJ3,OPRL1,PDYN,PENK,SERPINE2,PRKCB,PRKCG,SLC15A2,SLCO1A2,TPM3" Drug CID000008998 meso-erythritol Stitch 1.06E-03 1.00E+00 7.39E-03 8.41E-02 18 54 "ABHD6,AQP6,MIER1,SLC4A4,CACNA1B,CAPN3,CBS,CHM,TNK2,GAA,GK,GPD2,INPP1,MBNL1,SERPINI1,SST,ADHFE1,MCF2L" Drug 4989_UP Thioguanosine [85-31-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.06E-03 1.00E+00 7.41E-03 8.43E-02 45 182 "MRTFA,BIN1,EPB41L5,N4BP2L1,BAIAP3,RUNX1T1,SRSF11,EDRF1,EDNRB,EFNB3,ELN,NRN1,CORO2B,AMOTL2,FHL1,OGA,HBS1L,SRCAP,GFER,LYVE1,FICD,ICA1,KCNH2,MEF2C,MIA2,NACA,NEUROD1,NOVA2,MTRF1L,PNMA3,EMID1,PPM1E,RIMS1,RBM34,KIF21B,SP2,ZC3H13,ATP10B,THSD1,WSCD1,DICER1,TRIO,VLDLR,ZNF711,EMSY" Drug 1555_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 1.06E-03 1.00E+00 7.44E-03 8.46E-02 44 177 "NDRG2,ALCAM,BIN1,GAS7,ARRB2,DNAH17,CFLAR,CD86,CD38,ARHGAP33,CHN2,PICK1,AATK,CSF1R,PPP1R16B,CTNND1,RUBCN,DOCK4,MED12,FAM13A,KIAA1109,RUNDC3A,ITGAM,NCF2,NTRK2,OLR1,PDE4B,SMOX,PPP2R5C,PTPRE,SEC14L1,SGK1,SLA,SLC2A5,ARHGEF40,SPTAN1,CDK19,TSPYL2,SAMSN1,EPB41L3,PLCB1,PDLIM2,TPM4,CLDND1" Drug 4590_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.06E-03 1.00E+00 7.44E-03 8.46E-02 44 177 "APBB1,C5,IL33,MAP7,ARHGEF2,ADGRG1,EPS15L1,WHRN,CREM,AKAP12,ABCG1,CSNK1E,PHF14,CTH,PITPNC1,ARNT2,DTNA,ETV1,HBS1L,GPD1,GPM6B,SHISAL1,ITGA7,JAK2,NRCAM,PALM,PDE4B,PDE4D,PDGFRA,SMOX,PMP22,PPP3CA,PTHLH,RGS12,CCDC102B,LGR4,RBM34,TSNAXIP1,DOK5,ATP10B,EPB41L3,TBL1X,DNAH7,OSBP2" Drug CID000000823 glycerol-3-phosphocholine Stitch 1.07E-03 1.00E+00 7.46E-03 8.48E-02 43 172 "ACHE,ABHD6,PLA2G6,GPAM,PLA2G4C,PDE8B,ALDH7A1,CAPN3,CNTFR,PCYT1B,PLCXD3,ENPP6,GFRA1,GFRA2,MCHR1,PLCD4,IL6ST,LIFR,NTRK2,NTRK3,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ENPP2,PLCB2,PLCD1,GDPD2,PTAFR,RXRA,RXRG,SMPD3,PLCB1,ZFP91,SGK3,PORCN,GDPD5,PLD4" Drug 6187_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.07E-03 1.00E+00 7.46E-03 8.49E-02 42 167 "ARID1A,GRAMD1B,BIN1,DDO,CFLAR,BTRC,TPP1,CREM,CSNK1E,PDE4DIP,KIAA0513,OPTN,FAM13A,MBNL2,ETV1,FECH,KIAA1109,FGFR1,BAIAP2,CAP2,OGA,MSL3,MUM1,NRCAM,NUCB1,KCNK10,PDE4B,PDE4D,MBOAT7,PRKACB,PKN2,CNNM2,PTPRN2,HSPA4L,CPEB3,SLC15A2,SNCA,SPTAN1,CDK19,PSD3,FLRT2,ZBTB38" Drug CID000026627 lithium chromate Stitch 1.07E-03 1.00E+00 7.49E-03 8.52E-02 67 296 "ASIC2,ASIC1,ACHE,ADCY5,ADCY6,ADCY8,BRAP,SLC24A4,NT5C3B,APOC1,APOC2,APP,AQP6,ARHGDIA,ARNTL,DYNLL1,ATP1A1,ATP1A3,SLC4A4,ATP1B3,CACNA2D1,AIFM1,CHRM1,SLC24A2,CREM,CSNK1E,NR1D2,DRD1,ERBB4,SLC9B2,ACTL6B,FOXO3,GNAL,LOXL3,GRIA1,GRIK1,CIT,TNFAIP8L3,INPP1,MITF,NPY,PDPK1,PDYN,PMP2,PPP2R2C,PPP3CA,KANSL1,PRKCB,PRKCG,PRODH,ENOX1,SLC6A1,SLC8A2,SLC12A2,CUX2,SYNE1,TGFBR3,ICAM5,ACTR6,TRH,TRPC1,SLC13A3,ETNPPL,SLC30A3,SLC17A7,SNX14,NETO1" Drug ctd:D000517 alpha-Chlorohydrin CTD 1.08E-03 1.00E+00 7.53E-03 8.57E-02 183 942 "ABAT,ABR,ACADM,AS3MT,ACTN1,SORCS2,ALAD,SPARCL1,SEMA6A,ABCD2,LTBP4,KCNT1,AMPD3,AMT,PHYHD1,APP,AQP6,ARNTL,ALDH4A1,ALDH7A1,ADAM23,BID,ST3GAL5,MYRF,IL33,MMD2,CALB2,RGN,AIFM1,CD38,CDC25B,CDH2,CDO1,UBE2L6,SLC22A6,TPP1,SULT4A1,SUMF2,MFSD4A,CPS1,GDA,ABCG1,CRYM,CST3,FAM169A,CTH,GREB1,EDRF1,ACY3,MATR3,DAPK1,SCRN1,SIRPA,DBT,PITPNC1,DNAJC6,C2CD2L,GRIN3A,CALN1,NR1D2,DOCK2,RCAN1,GNE,RASGRP1,SEMA3D,EGFR,AASS,SLC43A2,EPS8,ERBB4,FAM198B,TUBB3,ATP8A1,DCTN2,FOLR2,ST6GALNAC3,B3GAT1,GABRB3,GABRG1,GCK,TUBA8,GHR,HPGDS,SPIN1,GLS,GLUL,GNAO1,LILRB4,GPD1,GRB10,GRIK3,GSTT2,MFSD2A,VSIG4,ACOT7,SCRG1,HP,HSP90AA1,IGF1,SCIN,IL6R,DIPK1A,JAK1,JAK2,SLC35G1,L1CAM,CAMK2N2,LSS,MAOB,MAPT,MRPL42,SESN3,CCDC80,MSRA,P2RY13,NFIA,NUCB2,IGSF11,P2RX7,PAH,PC,PDE1A,PDGFRA,ENPP2,PFKP,PGAM2,ABCB1,PIK3R1,PKM,PLTP,PSAT1,DRAM2,PRKCB,MAPK4,SLC22A23,LAMA1,PLPPR1,PTH1R,ELOVL2,PTPRD,PTPRN,NKAIN1,QDPR,ACSS3,VEPH1,PRIMA1,RPS20,SAFB,KIF27,SGK1,ABLIM3,SLC1A3,SLC2A5,LIMS2,SLC6A8,SP4,PBLD,EPB41L3,MAPK8IP3,RGL1,SEPT3,NSFL1C,PRRC2C,COBL,KLHL4,KIAA0930,SATB2,TRIM2,SYNE1,GPRIN3,TF,NPL,TPM3,TPM4,AMACR,TST,KCNT2,ZBTB16,SPIRE1,TUBA1A,RSPRY1,SLC39A12,AP3B2" Drug CID003050291 Prt-H Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "MED12,INPP5K,BRD8,GNAS,DDX25,NPR2,RXRA,RXRG,ARX,THRA,TRH" Drug CID006369389 V-X-A Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIK1,GRM5" Drug CID000004853 Pirmenolum Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "ASIC1,PDXK,ASIC3,CHRM1,KCNH2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug CID000100073 NSC332029 Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "TUBD1,TUBB3,TUBB4A,TUBA8,GPR162,TUBA1C,TUBB2B,TUBB2A,TUBB1,UBE3A,TUBA1A" Drug CID000011754 oxidized cholesterol Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "APOC2,APP,ABCG1,CYP46A1,HMGCR,BCO1,MTTP,RXRG,JMJD6,NETO1,JPH3" Drug CID000132846 "L-733,060" Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "CCKBR,FOXM1,B3GAT1,CRCP,GRIN1,GRM1,GRM5,HRH3,TAC1,TAC3,TACR1" Drug CID000011485 chloroacetanilide Stitch 1.10E-03 1.00E+00 7.70E-03 8.76E-02 11 26 "SLC4A4,KYAT1,ABCG2,GMPR2,HMGB1,RDX,GSTCD,AP1AR,SAFB,SOX10,TNNT1" Drug CID000031402 pregnanolone Stitch 1.12E-03 1.00E+00 7.83E-03 8.91E-02 26 90 "CACNA2D1,DBI,SLC29A4,STX2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,B4GALNT1,GFER,GLRB,GRIA2,GRIK1,GRIN2C,GRIN2D,MBP,MOBP,NPY,GPR85,SERPINI1,NETO1" Drug CID000107688 obidoxime Stitch 1.12E-03 1.00E+00 7.84E-03 8.92E-02 17 50 "SERPINA3,ACHE,AMT,BCHE,CBS,CHGA,CHRM1,CLTA,TOX,ENO2,B3GAT1,GFAP,MBP,TRHDE,SPP1,SYP,UCHL1" Drug CID000005040 NSC226080 Stitch 1.13E-03 1.00E+00 7.91E-03 9.00E-02 155 783 "BRAP,AGT,CDC42BPA,MAP4K3,MYH7B,ALDH4A1,ATM,EIF4G3,CFLAR,BMPR1B,IL33,CCNH,CCNT1,AIFM1,CD86,CDC42,CLTC,ABCG2,CNTFR,CREM,CS,CSF1,CSF1R,CSF2RA,CSF3R,VCAN,PITPNM3,ARNT2,CNNM1,EBI3,EGFR,EIF4G1,EIF4G2,EIF5,EIF1,EN2,ERBB2,ERBB4,ERCC2,RRAGB,F3,RPS6KC1,PTK2B,PPP1R1B,ACTL6B,FGFR1,FGFR3,FOXO3,EVL,FLT1,FYN,GAB1,RAPGEF6,ATP8A2,DNER,GFRA1,GFRA2,CSDC2,PPARGC1A,GLUL,OS9,GOLGB1,LILRB4,NR3C1,TNFAIP8L3,HSP90AA1,IGF1,IGFBP1,IL6ST,IL12A,JAK1,JAK2,KCNA1,KIT,LIFR,IL17D,SESN3,MYH3,MYH6,MYH7,MYO5A,MYO6,NF1,NTRK2,NTRK3,OLR1,PCSK5,PDGFRA,PDPK1,PENK,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PKD1,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,PRKAB2,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSMA6,PSMD13,ANKHD1,PTK2,PPP2R3C,QDPR,ARID4A,RDX,MYH14,FBXW7,RPS6KA2,RYR1,RYR3,MAPK12,FNIP1,SGK1,MYO18A,FNDC3A,PREX2,SLC6A1,TRERF1,COBL,TAC1,MLST8,CRTC1,TF,SIRT1,ACTR6,ZFP91,CABIN1,PIK3R5,PPIL6,TSC1,TSC2,EIF4ENIF1,UBE2H,RICTOR,XPO1,XRCC4,ZIC3,ZBTB16,SLC38A1,NUP214,JPH3" Drug ctd:D011224 Prazosin CTD 1.14E-03 1.00E+00 7.98E-03 9.08E-02 20 63 "ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ATP2A2,ABCG2,EDN1,PPARGC1A,IGF1,MYH6,MYH7,NPY,NPPA,ABCB1,PKM,PLCD1,MAPK3,SLC8A1,PLCB1" Drug CID000071329 dofetilide Stitch 1.14E-03 1.00E+00 7.98E-03 9.08E-02 20 63 "ANK2,CACNA2D1,ASIC3,AASS,EFS,KCNA4,KCNB1,KCND3,KCNH1,KCNH2,KCNJ3,KCNK2,ENPP2,HMGCLL1,RGR,KCNIP2,SCN4B,SCN3B,PEG10,KCNAB1" Drug CID000005033 radicicol Stitch 1.15E-03 1.00E+00 7.99E-03 9.09E-02 49 203 "ACLY,PHF12,APAF1,CACNA1A,CACNA1B,PLEKHB1,DCTN1,HP1BP3,DYNC1I1,ATN1,EGFR,EN2,ENO2,ERBB2,ERBB4,PRMT5,PPP1R1B,FOXG1,DCTN2,GFAP,PPARGC1A,TCERG1,NR3C1,PACSIN2,HSP90AA1,IGF1,MX1,NOS1,OGG1,PAH,ABCB1,PLIN1,PACSIN1,PPP5C,MAPK3,PSMA6,PTX3,QDPR,RAB3A,FBXW7,ATXN7,FOXRED1,SLC1A3,SYT1,SMG6,TRH,UBC,PRTFDC1,JPH3" Drug CID000006053 DMAB Stitch 1.15E-03 1.00E+00 7.99E-03 9.09E-02 35 133 "APAF1,CACNA1A,CACNA1B,CNR1,HDAC9,DYNC1I1,ATN1,EN2,ENO2,PPP1R1B,FOXG1,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSP90AA1,IGF1,OGG1,PAH,PENK,ABCB1,PACSIN1,QDPR,GSTCD,FBXW7,ATXN7,FOXRED1,SLC1A3,SLC20A2,SNCA,DDN,PRTFDC1,JPH3" Drug 1861_UP Triamterene [396-01-0]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "AMT,KCNAB2,APBB2,APC,FAM131A,ARNTL,ARRB1,N4BP2L1,KIF1A,SYNJ1,MAP7,ZMYM4,CHN2,FHL5,CSF1,CSNK1E,SEC14L5,ELN,KIAA1109,GAD2,INPP5K,TXNL4A,FERMT2,GUCY1A1,ELOVL5,SMAD1,MBP,GIT1,NTRK2,PIK3R1,PPP5C,PTN,RAB3IL1,RAD52,RAP1GAP,PAQR6,ZNF667,WDTC1,ARHGAP26,TSPYL2,CUX2,CHST8,PARD3,KAT6B,RBFOX2,PLPPR2,LAT2,PARP11" Drug 2126_DN Cloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADRA1D,ALAD,APC,APP,MARK4,SYNJ2,RAB29,CACNA2D2,HOMER3,IQCK,CSF1,PDE4DIP,DZIP3,TOX,ZFYVE16,TBC1D5,SIRPA,CNIH3,SPOCK3,CDON,SLC12A6,CNNM1,EGFR,ING4,F3,TRAF3IP2,DISC1,GPER1,SLC2A6,KLF12,SHISAL1,PDCD2,CDK14,RNF220,MCMBP,SH3BGR,SLC1A7,CDK19,SS18,NCDN,MAPK8IP3,FAM168A,KIAA1107,ZEB1,TRIM2,TMPO,CABIN1,ACTR3B" Drug 1825_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "BIN1,APOC1,APP,CDK10,CFLAR,SCARB1,SLC4A7,CSF1,CSNK1E,DZIP3,SDC3,ZFYVE16,TMCC2,DLG3,FEM1B,SPEG,BAIAP2,CGREF1,GAD1,INPP5K,USP19,FERMT2,SHISAL1,KIFC3,MEIS1,TAGLN3,ZNF862,NUCB1,ODF2,OGG1,PDPK1,KCTD15,NLE1,MED1,RIPOR1,GAL3ST4,FUZ,SLC1A3,PEX26,FAM214B,KBTBD4,ARHGEF9,DNMBP,WSCD1,ZEB1,NSD1,CABIN1,SMIM8" Drug 6262_DN Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADD3,ALCAM,ARRB2,BMP7,MTMR2,NFS1,REPS2,NCOR1,ABCG1,CTNND1,PPP6R2,KIAA0513,KIAA0586,GIT2,KIAA0753,PARD6A,DLG3,F3,SCML2,PDLIM5,GRB10,CLASRP,MAP4,MAPT,NCAM2,NEK1,OPA1,STRN3,PPP3CC,RAD51D,SEC61A2,ITSN1,SLC20A2,RCOR3,TMCC1,WDTC1,TACC1,DNMBP,TBL1X,OBSL1,BHLHB9,KCTD2,NPL,METTL3,HIRA,UBTF,VAV1,MAP3K12" Drug 5289_UP Flucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "KIAA1324,PLA2G6,ALCAM,CDC14B,PLA2G4C,DNAH17,ALDH4A1,KIF1A,BTRC,CAMK2G,ADGRG1,NMT2,VAX2,QKI,ABI3BP,PDE4DIP,INTS1,DAPK3,C2CD2L,FEM1B,EGFR,VPS26C,F3,FOXG1,PDLIM5,GAD1,B4GALNT1,GLYR1,ELOVL5,LSS,TM6SF1,NEUROD1,SLC25A23,PRKAR1B,WDR25,ITSN1,SLC1A7,KDM4C,SS18,FCHO1,INKA2,CEP68,POPDC3,TRIM2,KAT6B,ZMYND8,LMF1,NDRG4" Drug 2841_UP Tobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADORA3,NME5,ALCAM,BIN1,APLP1,BCAS1,SLC2A11,CA12,CACNB2,FOXN3,SPOCK2,SPOCK3,DMPK,HIPK3,KCNMB2,FGFR1,GLS,GNG3,FERMT2,STMN2,GRM1,LMO2,TM6SF1,ADAM22,PCDH9,PFKFB2,PLCD1,MINDY2,PTN,RAD51D,C1orf54,GAL3ST4,ZFHX4,RYR1,NLGN1,SLC1A7,ZSWIM8,NACAD,SYN2,DMXL2,DOCK9,TIAM1,TK2,VAV2,WNK1,PRDM2,ST7,RNF170" Drug 266_UP (+/-)-thalidomide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RBM10,CDK10,BARD1,BAIAP3,CHRM4,TPP1,TJP2,PCYT1B,IFFO1,CTNND2,CTIF,GIT2,FBXL5,MBNL2,MRNIP,LRRC23,FHL1,ARHGAP19,SYNPO,AGBL5,ITPKB,KCNC1,MBD1,MYL3,NELL2,NRGN,OPRL1,FSD1,MED1,DPF2,SAFB,ZNF821,SH3BP2,SHMT2,FNDC3A,ABLIM3,IFT122,KDM4B,WDTC1,EMC1,CLASP2,WWC1,TBL1X,SEZ6L,TSC2,LMF1,MPPE1,AAAS" Drug 7302_UP Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "APC,CDC14B,STX16,CACNA1A,CHN2,DNAJB5,HAPLN1,NCOR2,VCAN,CTNND2,DSCAM,DUSP9,EGFR,AASS,EN2,MTSS1L,ETV1,RRAGB,DISC1,GATM,GPM6B,GPR17,KLF12,TJAP1,SCIN,ADAM11,NDP,OPRL1,MBOAT7,PRPH,WDR25,PEX5,RALGDS,PAQR6,SCG5,PEX26,SNCA,PHLDB1,SYN2,ASTN2,TCF4,DNAH7,GPR161,SLC44A1,BEX4,CDK20,VAV2,KCNAB1" Drug 6657_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,BRAP,ADRA1D,PLA2G6,TRMT9B,AMPD3,CBFA2T2,RAB28,DNAJB5,CHD1L,AATK,VCAN,SDC3,PPP6R2,CNIH3,LYPD1,CHRDL1,HIPK3,PLXNC1,AASS,KIAA1109,ZNF44,SEPT9,GPM6B,HSF2,KHK,MAPT,TM6SF1,NF1,NFYA,CNOT4,PPP5C,MAPK7,PTHLH,RAB3A,NEK11,SUPT20H,PREX2,BTBD7,ZNF667,UNC5B,TROVE2,AHCYL2,TMEM121,CABIN1,TPM2,OSBP2,WIPF1" Drug 6630_UP Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ACTN2,NR0B1,ADGRF5,ALK,AMPH,APBB1,APOC1,ATP2B3,BMP7,GYG2,CACNA1G,CACNA1D,NEURL1,ARHGEF2,CHI3L2,CHRNB2,ABCG2,JAKMIP2,SPOCK3,DTNA,HIPK3,FABP7,ZNF589,FGF1,GFER,RUNDC3A,RND1,GRIK1,ADAMTS6,HTR2A,INPP5B,KCND3,NTRK2,OPCML,NLE1,RASGRF1,FRMPD1,ASAP3,DZIP1,VAMP1,TPM1,UBE3A,VAV2,VGF,ZNF24,SLC30A3,EVI5,PARP6" Drug 2437_UP Carbimazole [22232-54-8]; Up 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADD2,ARRB1,CFAP410,CA12,THSD7A,INA,ZFYVE9,CLCN3,CSF1,DAPK1,DBT,E2F5,EIF1,MTSS1L,CDHR1,ANKMY1,PTK2B,DLC1,PRKAG2,AFF2,TRAF3IP2,CPLX2,GFER,USP19,RUNDC3A,GLI2,KCND3,MX1,MAPK8,WDR25,PTCH1,PTPN13,CRTAC1,SH3BGR,FERMT1,TNIK,DOK5,MTCL1,WWC1,RPGRIP1L,TJP1,TMOD1,TNS1,RBFOX2,RPRM,SLC17A7,KCNAB1,ST7" Drug 2708_UP Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASPHD1,TRMT9B,AMPH,APBA2,APP,ALDH4A1,KIF1A,CAPN3,LARGE1,TAOK2,NRXN2,STOML1,PICK1,SLC4A8,HAPLN1,NCOR2,AATK,RIMS2,EXOG,DLC1,GAB1,SIGLEC8,SEPT9,POLL,GRK4,SPACA9,HTR5A,SCAMP5,MMP17,OMG,OXTR,FSD1,LRRN3,RGS4,SNCA,SPTAN1,TACR1,ROBO3,TAL1,TEX15,CHST8,TMOD1,TNS1,RUNDC3B,FLRT1,VAV2,WNT7A,SLC17A7" Drug 4735_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG3,ADRA1D,TRMT9B,AMPD3,MADD,CAMK2G,NEURL1,TAOK2,SLIT2,CLU,COL9A2,RIMS2,SLC12A6,SUGP2,SORBS3,F3,ZNF589,KIAA1109,FGF12,FHL1,AFF2,HTATSF1,POLL,STON1,GRM1,GRM8,KPNA5,MAP4,KITLG,MMP16,MSI1,ADAM22,ZNF862,MYT1,NUMA1,SERPINI1,MSANTD2,GSTCD,SELL,ZNF821,SLC1A7,BTBD7,COA1,PCDHA5,TNS1,HIRA,MICAL1,HPS4" Drug 6345_UP Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,MRTFA,PPP4R4,KIF1A,FUBP1,CACNA2D2,QKI,CSF1,CSNK1E,RIMS3,MFAP3L,DMPK,EDN3,EFNB3,IRAK4,TNK2,FGFR1,TBR1,GNAO1,GPR17,RASSF8,SHISAL1,MDFI,CNOT4,NUMA1,PDE1C,PDE4D,PENK,PRKAR1B,MAPK7,GRAMD1C,PLPPR1,RAD52,ASIC4,IL17RB,ZFP30,FRMPD1,ELMO2,KDM4C,LHPP,VPS13A,ARHGEF12,CRTC1,TRIO,VGF,WNK1,STMN4,SEMA3B" Drug 6502_DN Denatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "DOC2A,TRMT9B,APC,PPFIA3,CFLAR,SYNJ2,GYG2,BTRC,PLAA,SH2B1,CSNK1E,SIPA1L1,PDE4DIP,FAM169A,SDC3,GIT2,DBT,CDON,DSCAM,DISC1,AHDC1,GOLGB1,GRIK5,GRM1,INPP5B,KCNH2,KHK,IPO5,VWA5A,SLC25A23,PPP5C,TMEM104,KIF16B,AMBRA1,ZNF365,PKNOX2,SLC20A2,ZKSCAN3,ZHX3,ZC3H13,TROVE2,FBXW11,RPGRIP1L,VGF,MICAL1,ZNF74,HPS4,ST7" Drug 983_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ABHD6,CDC14B,BCL7A,BMP7,SYNJ2,ARHGEF7,CCNT1,REPS2,SRSF11,B4GALT6,AKAP7,NECTIN3,ENTPD4,NCOR1,SOCS5,PDE4DIP,PPP6R2,SPATA2,FBXL5,RBM12,PHF20L1,F8,FAM49B,ZNF276,TXNL4A,GRB10,FICD,ATXN2L,PDCD2,PDE3B,RETREG2,MINDY2,PRKAR1B,PRODH,NKAIN1,QDPR,ROBO1,FOXRED2,MAPK12,SCMH1,ZKSCAN3,MAPKBP1,PDZRN3,SPART,ASTN2,IQCE,KIAA0930,CABIN1" Drug 7278_UP Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RALGAPA1,MRTFA,CFLAR,PTBP2,RUNX1T1,KRIT1,SCARB1,SRSF11,TAOK2,ZFYVE9,CLCN4,NIPBL,AKAP7,RIMS3,DBT,IRAK4,C3orf18,VPS13B,F3,FGF13,FGFR1,TRMO,ATP2C1,SYT17,KIF3A,HSF2,IFI16,TJAP1,MIA2,NOS1,NUMA1,MAPKAP1,MAPK3,FAT4,PPP1R9A,KDM4D,SLC14A1,TMCC1,ARHGAP26,CEP68,ARHGEF12,MICAL1,LMF1,WNK1,EMSY,PLSCR4,PHTF2,RNF146" Drug 3035_UP Sulconazole nitrate [61318-91-0]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "LGR5,SEMA4G,CCDC181,HAP1,MTMR7,CBFA2T2,REPS2,MAGI1,CRYBB1,RGS6,SUSD5,CNTNAP2,RIMS3,SPOCK2,JAKMIP2,EDN3,RASGRP2,EPHB1,CHST15,CAMSAP1,GABRG2,RUNDC3A,GRIA4,CACFD1,KLF12,HTR2A,KCNA4,KCNN3,L1CAM,ADAM22,OPRL1,CLDN11,EPN1,POU6F1,PPARA,LRRC49,MYH14,ASIC4,SH3GL3,PREX2,SMTN,SLC11A1,SHANK2,LHPP,ST5,TMOD1,TRPC1,PMEPA1" Drug 4020_DN "(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,ADCY6,NME5,BIN1,APC,SEMA4G,ARRB2,PDE8B,MARK4,ALDH4A1,ATP2A2,SYNJ2,C5,SOCS6,DNAJB5,HOMER3,BAG4,CNTNAP2,PARD6A,DPH1,EDN1,SIDT2,PLEKHO1,COQ7,SRCAP,GLRB,KIF5C,LIG4,SLC11A2,CDK14,RC3H2,PTPA,CNTLN,ZSCAN32,RGS7,PAQR6,IL17RB,ST6GAL1,SLC6A9,CAND2,CDK19,TCF4,TRIM2,NSD2,ZNF711,NDRG4,EMSY,EVI5" Drug 1485_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "KCNAB2,APBB2,APC,BCAS1,CFLAR,SYNJ2,SCAPER,TAOK2,SIPA1L1,GREB1,EDRF1,DAPK3,DBT,MFAP3L,MAGI2,DMPK,EDNRA,MBNL2,DMTN,RRAGB,F3,FOXG1,GPR153,ALDH1L1,GLYR1,ADAMTS13,NR3C1,IL1RAPL1,INPP5B,KCNH2,KCNJ5,MATK,BCO1,NPTX1,PLCD1,ZNF493,ANKRD6,CXXC4,USP33,ELOVL4,EXOC7,IQCE,ARHGEF12,CHST8,AP4E1,CDK20,FLRT2,KCNAB1" Drug 3051_UP Bemegride [64-65-3]; Up 200; 25.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ABHD6,ADCY6,MTUS1,SEMA4G,ARHGDIG,CFAP410,CACNG1,CDH10,MAGI1,CACNA2D2,LHX2,RAB26,CHD5,USP6NL,DMD,TRAPPC9,DSCAM,EDN3,EPB41L1,LRRC17,FHL1,ZNF276,C2orf72,IL6ST,KIF5A,KIFC3,PCSK5,PDE1C,DCHS2,CNNM2,BCAS3,RAB3A,GAL3ST4,KCTD17,SEMA6D,SCNN1D,SYBU,SLC11A1,DOK5,PEG10,NFASC,ATP10B,TAC1,PHF24,AP4E1,ICAM5,DAAM2,MAP3K12" Drug 2486_DN Trimethadione [127-48-0]; Down 200; 28uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,NDRG2,MTUS1,SYNJ2,CLCN4,IQCK,HINFP,ABCG1,AATK,CSNK1E,USP6NL,TM9SF4,DTNA,MBNL2,TUBD1,LRRC23,DLC1,GABRA2,ZMYND11,SRCAP,USP19,GRM1,ICA1,TJAP1,JAK2,MYO7A,SLC11A2,PLCD1,PTAFR,RIPOR1,GSTCD,SEC14L1,MRAS,DOCK10,PEX26,EPN2,FAM214B,ZKSCAN3,TSPYL2,TROVE2,SEPT8,PDLIM2,WWC1,TCF4,THBS4,ICAM5,TRPS1,NUP214" Drug 3465_UP Amrinone [60719-84-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,AK2,SRPX,MRTFA,AMPD3,AMT,KCNAB2,AQP4,CFLAR,ZFYVE9,HOMER3,SH2B1,CSF1,DAPK3,PARD6A,TUBB4A,FAM49B,GABRA2,ERAP1,SEPT9,GFER,USP19,GLS,STON1,SPACA9,MAP4,BCO1,ZNF862,NTRK2,SERPINE2,ZSCAN2,RAD52,GTDC1,RGS12,RNASEL,FBXW7,SMTN,FAM214B,TMCC1,KDM4C,UNC5B,CDK19,PHLDB1,PLCB1,ATP11A,ARHGEF12,THRA,NT5M" Drug 6275_UP Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADORA1,SYT13,AMPD3,ANK3,APC,GAS7,ARRB1,RGS20,MARK4,AZGP1,CFLAR,SYNJ2,MTMR2,TAOK2,QKI,CSF1,SIPA1L1,EDN1,EDNRB,SUGP2,CEND1,ZNF589,GPR153,COPS8,PCLO,JAK2,KCND3,PACRG,MAP4,MMP16,MPP2,NF1,P2RY1,CAMKV,RETREG1,ZCWPW1,ZNF365,WDTC1,SOX2,ZHX3,SPTAN1,PSD3,TNS2,TRPM2,FAM155A,XRCC4,SLC30A3,SLC17A7" Drug 4130_UP Pheniramine maleate [132-20-7]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "CDC42BPA,SEMA4G,ATP1A2,BCL7A,SYNJ1,SYNJ2,CACNA1G,BAIAP3,RUNX1T1,CHN2,CLCN4,CRY2,DAPK1,DAPK3,TMCC2,DYRK1A,SIDT2,SCML2,FOXF2,B3GAT1,ALDH1L1,GNAL,GOLGB1,ACOT7,LSS,MSI1,MX1,MYT1,OMG,PACSIN1,GDPD2,PTAFR,ZSCAN32,RAD52,C1orf54,RGS10,ZFP2,RASA3,FBXO11,SHANK2,NMNAT2,SYT11,SEMA4A,KIAA1107,HIF3A,TEK,PIK3R5,PLSCR4" Drug 6894_DN SB 203580; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RALGAPA1,ABR,OGT,APBB1,SCARB1,LARGE1,CHN2,CHRNB2,WHRN,PDE4DIP,TOX,ATN1,RCAN1,EDNRA,FAM13A,APH1A,ING4,MRNIP,HSD17B14,ANKMY1,SCARA3,GPER1,MAN1B1,TM6SF1,NFIX,RETREG1,PLEC,MED1,MAPK7,GRAMD1C,APTX,GON4L,WDR25,RGS3,ASAP3,UNC5B,LHPP,NACAD,VAMP1,TMPO,R3HDM1,HIRA,LMF1,NSD2,WNT7A,WNK1,EMSY,DPF3" Drug 4470_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADORA1,AGT,ALK,SEMA7A,APAF1,GAS7,ASCL1,ATP6V0A1,NRP2,GYG2,LDLRAD4,THSD7A,CHN2,TAOK2,STOML1,COL9A3,CHRDL1,EDNRB,EFNA3,MRNIP,FYN,GAB1,PTGDR2,ICA1,LAMA2,MYT1,P2RY1,PCDHGC3,PDE3B,SMOX,PURG,POU6F1,PTPRN2,RFX2,RGS12,TCP11L1,HKDC1,ZNF334,ZHX3,PLCB1,MCF2L,SMG6,PCDHGA10,PCDHA5,DNAH7,TRPC3,VAV2,LAT2" Drug 2646_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "TKTL1,TRMT9B,SEMA7A,GAS7,DDO,SEMA4G,MARK4,CADM3,RUNX1T1,ASIC3,SLIT2,COL9A3,LRIG1,RIMS2,PPP6R2,SMG7,TMCC2,DMPK,EDN3,EDNRA,SIDT2,ERCC2,IQCG,DPYSL4,GPR153,GABRA4,SEPT9,PCDH17,ATF7,GRM2,GUCY1A1,ATXN2L,IRF8,INPP5B,ITGA7,KCNJ4,AFF1,PRPH,PREX2,ZCCHC24,EMC1,HECW1,SPTAN1,TNS1,TRPC3,HIRA,PLPPR2,NDRG4" Drug 7270_DN "Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "BIN1,EP400,APBB2,APC,APLP1,APP,ALDH4A1,ATP2A2,MPDZ,CFLAR,SCAPER,CCNT1,SLC4A7,FAM169A,ZFYVE16,SPATA2,SGSM2,STX2,ERCC2,VPS26C,ZNF589,BAIAP2,CINP,FICD,SLC2A6,MAPT,MN1,ZNF862,NUMA1,OGG1,MBOAT7,POLG,PPP5C,ELOVL2,RAB3IL1,SUGCT,TCP11L1,FAM214B,KBTBD4,IFT122,CDK19,NXT2,AGTPBP1,KIAA0930,RBFOX2,OSBP2,MAP3K12,MPPE1" Drug 5420_DN Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,APBB2,ALDH7A1,CFAP410,AKAP7,CHD1L,CRY2,GPRASP1,KIAA0586,DBN1,MFAP3L,DSCAM,IRAK4,EPB41L1,KAT8,ZNF589,RUNDC3A,ZNF276,TXNL4A,MSL3,GPD2,GPR19,GPER1,SPACA9,HNMT,DHX35,KHK,LSS,MDM4,MMP16,NPR2,ELOVL2,PEX5,NKAIN1,GTDC1,RGS12,RNASEL,SMTN,KIF13A,PHLDB1,PLCB1,SEMA4A,TK2,KCTD2,VGF,ZNF74,PHTF2,SSPN" Drug 6362_UP Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "PPFIA3,PPP4R4,ARRB2,NRP2,ST3GAL5,CACNB2,ARHGEF1,TPP1,PICK1,COL9A2,SLC4A7,IFFO1,CREM,PDE4DIP,ARHGAP24,SMG7,E2F5,EFNA3,EFNB3,TUBD1,COQ7,STX2,FGF1,GHR,CRCP,GLS,PRRC2B,KCNMA1,VWA5A,NUMA1,CCSER2,RETREG1,MED1,PTN,RAD52,SLC4A3,FAM214B,SPART,LHPP,PHLDB1,PCDHGA10,TRIO,RUNDC3B,HIRA,OSBP2,ZNF711,WNK1,EVI5" Drug 7334_DN Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SERPINA3,ASIC1,CDC42BPA,APC,APOC1,PPFIA3,BMP7,DNM2,DTNA,FEM1B,SIDT2,SUGP2,SORBS3,ENO2,CDKL3,ANKFY1,GALC,SYT17,INPP5K,ZNF276,PRRC2B,DHX35,INPP5B,ITPKB,MAP4,MAPT,MATK,KITLG,NUMA1,KCTD15,LRP12,PMS2,GSTCD,ATXN7,FUZ,SCMH1,TSPYL2,CLASP2,STX1A,IQCE,SZT2,AHCYL2,KAT6B,CABIN1,KCNAB1,MPPE1,SMIM8,RNF170" Drug 2162_DN Gelsemine [509-15-9]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "PKP4,PPP4R4,MARK4,SYNJ2,SCAPER,C5,USP2,FOXN3,RAB33A,CNTN1,CREM,ARHGEF10,ZNF337,TM9SF4,RIMS3,ING4,TNK2,RASGRP2,ZNF589,AFF2,SRCAP,USP19,GPR19,CACFD1,MX1,MYT1,CNOT4,MBOAT7,POU6F1,MINDY2,MAPK3,ZSCAN32,PEX5,RAB3IL1,RGS3,DCUN1D2,PREX2,ZKSCAN3,KDM4B,ZCCHC24,DOK5,PLCB1,ATP11A,RBFOX2,TPM1,ZKSCAN5,ZNF225,PHTF2" Drug 6153_DN Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,KIDINS220,MTUS1,SEMA4G,N4BP2L1,CFLAR,BTRC,RAB28,CRMP1,EDRF1,KIAA0513,DCT,CDON,MRNIP,PDLIM5,SEPT9,ZNF276,SPACA9,GRM1,BTN2A1,GSN,ITIH2,MAP4,CNOT4,NPR2,PLP1,PTPN13,RIPOR1,MARCH1,RGS10,MAP6D1,ATXN1,GALNT10,RASA3,PPM1E,CPEB3,BCAN,FAM214B,SLC11A1,IQCE,TCF7L2,SYNE1,TNS2,VIPR2,LMF1,CLIP2,ZFP37,ZIC3" Drug 3417_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASPHD1,AP2A2,MARCH3,EIF4G3,CFLAR,SOCS6,QKI,LRIG1,CSNK1E,DBT,SMG7,SIDT2,ABI2,EZH1,CGREF1,GRB10,KIF5C,LIG4,MAP4,NFYA,CCSER2,SMIM7,MBOAT7,TNPO2,POLR2F,WDR25,NKAIN1,RAB5B,ATG16L1,ZCWPW1,NCBP3,TRAPPC13,BTBD3,EPN2,ARFGAP1,ZSWIM8,TSPYL2,CLASP2,TROVE2,EXOC7,IQCE,NR2C2,TRIO,HIRA,ZNF142,REEP1,MPPE1,RNF170" Drug 1435_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "GRAMD1B,BEGAIN,AMT,CDC42BPA,SEMA7A,PPFIA1,ATM,CFLAR,NAE1,MTMR3,OSGIN2,CA12,CHN2,ZNF337,TM9SF4,ING4,BSCL2,VPS26C,CD320,F3,PRKAG2,CAMSAP1,ATP2C1,OGA,FYB1,GPR12,HRH3,AGBL5,RBPJ,KCNJ3,MYT1,NNAT,NTRK3,PAK3,PLEC,QRICH1,TMEM206,ZNF671,SUPT20H,SLC11A1,KBTBD4,LMO3,ZC4H2,MLC1,TNS1,TSC2,PRDM2,ZNF248" Drug 6684_DN Hydrocortisone base [50-23-7]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "TRMT9B,BIN1,PDE8B,SLC4A4,MYRF,CBFA2T2,ABCG2,TENM4,PDE4DIP,CNTNAP2,KLHL3,CHRDL1,MFSD10,CDKL3,PDLIM5,TRAF3IP2,C1QL1,TDRKH,GRK4,IL6ST,TM6SF1,MMP16,NOS1,PAK3,RETREG1,PRPH,PTHLH,PTN,PTPRN2,TMEM231,RAD52,C1orf54,FAM184A,KIRREL1,SCG5,FBXO11,SLC14A1,UNC5B,SPTAN1,KIAA1107,ARHGEF12,TK2,TPM2,SSBP2,HIRA,LMF1,KCNAB1,DPF3" Drug 6812_UP Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,ADORA1,PLA2G6,BIN1,BAIAP3,CAMK2B,CDH2,CLGN,CNOT8,RAB33A,PDE4DIP,SEC14L5,RIMS3,DCT,DTNA,DUSP9,EDN3,EFNA3,NCALD,ACSL4,CAMSAP1,HPCAL4,FYN,GAD1,RND1,CRCP,RAB30,HNMT,IL6R,MDM4,AFDN,CLDN11,PDE1C,PTHLH,ZSCAN2,EMID1,ZCCHC24,CAMTA2,MAPK8IP3,VAMP1,ATP11A,SMG6,TK2,DAAM2,TRO,LAT2,SPHK2,SLC17A7" Drug 4664_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RALGAPA1,TTYH1,ASPHD1,BBOX1,APBB1,CACNB2,MTMR7,TMEM257,CDH10,CHI3L2,STOML1,VAX2,HOMER3,ABCG1,C2CD2L,SRGAP3,AK5,DRP2,HIPK3,EZH1,FYB1,SIGLEC8,GPR75,GNAL,GRIK3,GRM8,KLF12,KCNN1,VWA5A,LSS,GIT1,MYO7A,P2RX7,NLE1,ZNF426,PROX1,PTH1R,RAD51D,RGR,ARHGAP26,ZBTB43,TROVE2,KIAA1107,RPGRIP1L,UGT8,VIPR2,ZFP37,JPH3" Drug 2918_UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "KIDINS220,AMPD3,CDC42BPA,ANK3,APBB2,APOC1,ARHGDIG,CADM3,RHBDL1,CCK,CBFA2T2,CNTN1,IQCK,SLC4A8,SH2B1,ABCG1,CDON,EIF4G2,RASGRP2,TLR7,CSDC2,CACFD1,GRM1,HMGB1,IL12A,MDFI,SCAMP5,ADAM22,MYO6,ZNF862,FXYD7,NEUROD1,PDE4A,PDGFRA,KCNIP1,CXXC4,SPTAN1,DIP2A,PLCB1,KAZN,EXOC7,PCDHGA10,PCDHA3,ATP13A2,TK2,SEZ6L,VIPR2,SLC13A3" Drug 2157_UP Austricine [10180-88-8]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,APAF1,CASK,SEPT7,SLIT2,NMT2,DNAJC6,EIF1,FLNC,CAMKK2,GPR153,GAP43,ALDH1L1,HTR2A,KPNA5,MEF2C,MOBP,TAGLN3,NPPA,NUMA1,PENK,PFKFB4,STRN3,PPP5C,BCAS3,PTAFR,PTPRN2,ZNF493,BSDC1,RFX2,RPS20,ZCCHC24,SOX10,HECW1,SPART,SS18,SEPT8,FAM168A,SYN2,TBCEL,AHCYL2,UBE3A,KLC2,ZNF32,SPHK2,EVI5,TIGD6,SENP7" Drug 4603_UP Practolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "AQP4,ADGRB1,CACNA1G,RUNX1T1,NRXN3,RGS6,NOS1AP,RIMS3,HEPH,MAGI2,ARNT2,DRP2,DYRK1A,EDNRB,PLXNC1,ZNF549,AGAP2,FLT1,DOT1L,FYB1,TOX3,GPR45,IGF1,ITPKA,KCNA2,AFF1,MMP16,MYCN,MYT1,NF1,PDE4D,PENK,CCDC102B,PRR5L,KANSL3,ZHX3,DDN,LHPP,VAMP1,ARC,TACR1,KAZN,TRIM2,TPM1,PRMT8,FLRT2,VIPR2,WIPF1" Drug 6727_DN Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,EP400,TAOK2,KIAA1549L,TENM4,MICAL2,FAM169A,DZIP3,PPP6R2,MFAP3L,AASS,MRNIP,VPS13B,SPEG,ETV1,ANKMY1,RRAGB,ZNF589,SORBS1,FYB1,DENND2A,GLRB,POLL,KIF5C,MGAT3,NF1,OGG1,PRKAR1B,GRAMD1C,PRPH,SYTL2,FOXRED2,ATXN7,LIMCH1,PHLDB1,SYT11,KIAA1107,RPGRIP1L,NSD1,ARHGEF12,TK2,TRPC1,PLPPR2,VGF,WIPF1,XRCC4,ZNF45,ADAMTSL3" Drug 4189_UP Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC2,ADRA1D,APC,CDK10,ZSCAN18,BACH1,NRP2,MYRF,CA12,CACNG1,ARHGEF2,LARGE1,CHRNA4,RAB26,HOMER3,IPCEF1,PDE4DIP,ZEB2,EDN3,F5,CORO2B,LYVE1,GNAL,GRIK3,GPR45,HPSE2,KCND3,MARK1,MMP16,ADAM22,NTRK2,OPRL1,LRRN3,PRKAR1B,PTH1R,PTPRG,ENOX1,GAL3ST4,PBRM1,SLC6A8,ARHGEF40,MAPK8IP3,SEZ6L,TRH,VAV2,WNK1,DNALI1,SLC17A7" Drug 3864_UP Ethisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "LTBP4,SEMA7A,APOC1,SEMA4G,PTCH2,CFAP410,CAMK2B,CDO1,CHI3L2,FADS2,SULT4A1,PICK1,AKAP5,CRY2,TMCC2,TRAPPC9,ATN1,EN2,ETV1,DLC1,AGAP2,FYB1,SIGLEC8,CPLX2,SRCAP,CSDC2,GPER1,NR3C1,IRF8,KCNJ5,KIT,MSR1,FXYD7,NAP1L1,PDE1C,TMOD2,RYR1,ASIC4,BCAN,SLC1A2,SNAP25,ZSWIM8,IZUMO4,ARHGAP26,SPTB,ARC,HEY1,PARP11" Drug 5452_DN Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,PLA2G6,MARK4,GYG2,BAIAP3,CBFA2T2,CLGN,FADS2,SDC3,CTNND2,TBC1D5,DPH1,RGS17,EML1,DMTN,DENND4A,FER,FHL1,CINP,AHDC1,GLYR1,GPD2,GPM6B,KIF5C,KPNA5,MBD1,NDUFA5,CNOT4,NPR2,NTRK2,SMIM7,MED1,MAPK8,GON4L,PEX5,RAD52,RGS10,SBF1,SLC1A7,RBM34,WDTC1,SPART,INKA2,TMEM121,ZFP37,EPM2A,KAT6A,ZNF248" Drug 2622_UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,ADORA3,NME5,MARK4,LDLRAD4,TPP1,FADS2,AKAP7,WHRN,ARHGEF10,PDE4DIP,CTNND2,MFAP3L,SPOCK3,CDON,SLC12A6,ST8SIA3,TNK2,RCAN2,DLC1,SEMA4D,GPR153,GAD2,SRCAP,C1QL1,GNAL,GNAS,GRIK5,GRM2,GRM8,HAS2,KCNMA1,LMO2,ADAM22,ZNF862,NOS1,NPY,SAMD9,SNAP25,KDM4C,ZC3H13,IQSEC2,SMG6,CRTC1,HIF3A,TLR4,TIGD6,AP3B2" Drug 2201_DN Foliosidine [2520-38-9]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,ADRA1D,AMPD3,APBB2,GAS7,KIF1A,INA,CDH10,LARGE1,HOMER3,CSF3R,PDE4DIP,PPP1R16B,DGKG,RCAN1,EEF1A2,EFNA3,PLXNC1,ING4,RRAGB,TRAF3IP2,GALC,GPR19,GPR22,GRIK5,CACFD1,PADI2,ITGAM,MAP4,SCAMP5,NCAM1,PLP1,PTPA,PTAFR,RAP1GAP,SBF1,SLC1A7,LIMS2,FAM214B,TMCC1,CAND2,FCHO1,PSD3,AHCYL2,RBFOX2,VIPR2,UPF3A,EVI5" Drug 6350_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,PPFIA3,ALDH4A1,STX16,ST3GAL5,ARHGEF1,NRXN3,CLCN3,PICK1,ARMC8,IFFO1,CREM,AATK,CSF1R,CSNK1E,RIMS3,PARD6A,EGFR,IRAK4,EN2,F5,KIAA1109,B3GAT1,GAD2,ELOVL5,IRF8,ITIH2,KPNA5,LIFR,NDP,NPR2,TREM2,PDE2A,PLCB2,PLCD1,GRAMD1C,WDR25,TMEM206,SLC11A1,SLC20A2,PHLDB1,KAZN,KIAA1107,PSD3,CRTC1,VAV2,LAT2,REEP1" Drug 1797_DN Trichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADGRF5,APC,APOC1,APP,MARK4,ST3GAL5,PLEKHB1,EPS15L1,SLC4A7,CSF1,GIT2,TRAPPC9,EFNA3,EIF5,TNK2,EPB41L1,SCML2,SCARA3,PDLIM5,FAM49B,INPP5K,GART,ZNF276,GLUL,GPER1,MUM1,DIPK1A,KHK,SMAD1,MX1,ZNF862,NFYA,PFKFB2,PLEC,SLC25A23,MBOAT7,PTHLH,RGS4,ELMO2,CDK19,SS18,DNMBP,IQCE,WASHC4,KAT6B,FAM155A,UPF3A,SMIM8" Drug 4020_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ACHE,ADARB2,AMT,PPFIA4,DDO,PTCH2,ATP2B3,ADAM23,BAIAP3,CCK,GPR37L1,AKAP5,CSF1,RIMS2,TOX,INTS1,ZEB2,SRGAP3,DRP2,EPB41,FGFR1,AGAP2,SEMA4D,EFCAB2,FYB1,SIGLEC8,GATM,LYVE1,RUNDC3A,CACFD1,HTR5A,IGSF1,KCNC1,KCNJ5,ADAM22,NTRK3,PALM,ENPP2,LRRN3,KANSL3,CXXC4,SOX15,SPTAN1,ADGRL3,THRA,PRMT8,NT5M,NLRP3" Drug 1690_DN Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "LTBP4,DGKD,SHROOM2,PDXK,MADD,ARNTL,ARRB1,KIF1A,BCL2L2,BCL7A,SYNJ2,CCNT1,NIPBL,AKAP7,PDE4DIP,PPP6R2,GIT2,CELSR3,PHF20L1,STX2,EZH1,CAMSAP1,CGREF1,GPD2,IL6ST,KIF5C,LIG4,MPP2,GIT1,NRGN,PDE3B,FBXW7,RXRA,SEC14L1,SLC20A2,MAPKBP1,WDTC1,SYT1,TCF7,TCF7L2,TRIM2,TNS2,CABIN1,ZMYND8,HIRA,CADM1,MAP3K12,RNF170" Drug 1985_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARRB2,BCL7A,BMP7,CCNT1,SLC4A7,CREM,NCOR2,AATK,PPP1R16B,FBXL5,DNM1,MED12,MRNIP,IGSF6,EFS,PIPOX,PCDH17,GNAS,GNG3,GNG4,GRIK5,HRH3,IGF1,TJAP1,KCNH2,MT1M,NF1,NRGN,NTRK3,PDE4A,PLEC,FTO,PTPA,ARID4A,TMEM206,ITSN1,SYBU,ARHGEF40,ZCCHC24,ZHX3,DIP2A,OBSL1,AHCYL2,CDH22,VIPR2,ZNF189,NT5M,ZNF248" Drug 6127_UP Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASPHD1,SEMA6A,FAM135A,BIN1,BMP7,RUNX1T1,SOCS6,CHRNB2,FAM149A,DZIP3,MFAP3L,KLHL3,SV2B,ST8SIA3,OPTN,EIF1,RASGRP2,CEND1,AFF2,KHDRBS3,ZMYND11,HPGDS,HTR5A,KCNA2,NEFM,NHLH1,NOS1,CNOT4,P2RY1,PCDH9,PGAM2,DUSP26,PLCD1,SLC25A23,PPP2R2B,PPP5C,PRKCZ,CNNM2,ELOVL2,SLC11A1,TMCC1,DOP1A,TNIK,MAPK8IP3,PLCB1,WWC1,PARD3,KLC2" Drug 1970_DN Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "APP,SEMA4G,FOXN3,CLTB,SMARCAL1,SPATA2,SMG7,NR1D2,DTNA,CEND1,KIAA1109,SUCO,SEC23B,DBF4,GLS,OS9,ITGAV,KCNN2,IPO5,MITF,GIT1,MYO5A,NEFH,PFKFB3,PPM1B,MAPK9,C1orf109,RAP1GDS1,RDX,EXD2,ITSN1,BCAN,SLC2A5,ELMO2,MAPKBP1,MAPK8IP3,RGL1,DMXL2,SIRT1,TK2,TMPO,R3HDM1,PIK3R5,TSN,ZBTB14,ZNF142,ZNF184,SNX27" Drug 6480_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ABHD6,SEMA7A,APBA2,KCNAB2,PPFIA3,SLC4A4,KSR1,MTMR3,THSD7A,RHBDL1,NEURL1,CHRNA4,RAB33A,DNAJB5,COL9A3,CHD5,PDE4DIP,RIMS3,CTIF,CHRDL1,ABCC9,AASS,EIF4G2,EFS,CACNG3,ST3GAL6,TBR1,GFER,GUCY1B1,ITIH2,KCND3,LMO2,MBD1,ADAM22,TREM2,PTPRB,RALGDS,EMID1,FRMPD1,COA1,SOX10,NCDN,TRIM2,FAM189A1,GPR161,SEZ6L,HRASLS,PHTF2" Drug 1723_UP Bromperidol [10457-90-6]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADCY6,APC,APP,ARNTL,ADAM15,AZGP1,WASF1,ENTPD6,TAOK2,AKAP7,OSBPL3,DOCK4,TM9SF4,C2CD2L,PCOLCE2,TUBD1,CEND1,SH3YL1,KAT8,AGAP2,INPP5K,RUNDC3A,CACFD1,KLF12,AGFG1,KCNN1,KIF5A,KIF5C,MYT1,NUCB1,PIK3R1,RETREG1,NLE1,MINDY2,PTX3,CLIP1,AMBRA1,BTBD3,MAPKBP1,TBL1X,MGRN1,EHBP1,PARD3,KAT6B,CHST5,ZMYND8,FLRT1,ZNF142" Drug 6320_UP Nimodipine [66085-59-4]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,ARID1A,PKP4,APBB2,APC,APOC1,CDC14B,FGF17,SCAPER,LDLRAD4,SYNGR3,WHRN,AATK,SUSD5,ATN1,DUSP9,PLXNC1,MRNIP,STX2,BAIAP2,TBR1,ZMYND11,GLRB,GPER1,GRIK5,GSTM5,GUCY1A2,ATXN2L,KCNN1,VWA5A,PALM,PFKFB2,CCSER2,PTCH1,PTPRE,RAB3A,RALGDS,KCTD17,TCP11L1,STUM,SH3BP2,KDM4C,MAPK8IP3,CRTC1,TIAM1,LAT2,PARP6,RNF170" Drug 3970_UP Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "DPF1,ADD2,MRTFA,TRMT9B,APAF1,MARK4,CADM3,GYG2,HAP1,CLGN,GPR37L1,CLCN4,RIMS3,INTS1,SV2A,DPP6,ST8SIA3,ELN,IGSF6,ZNF391,FGFR3,RASL10A,GPD1,GRM8,GUCY1A2,IGF1,KCNC1,ADAM11,MDFI,ADAM22,TAGLN3,NOVA2,NTRK2,PALM,ZNF426,CNTLN,PTAFR,RAD52,RASA3,FBXO11,PKNOX2,ZSWIM8,NMNAT2,TAL1,SYNE1,RALYL,TMOD1,AMACR" Drug 4757_DN PNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SRPX,BIN1,CDC42BPA,FAM131A,PPFIA3,ALDH7A1,ST3GAL5,CFAP410,CA4,ARHGEF1,LHX2,WHRN,ABI3BP,NCOR2,PDE4DIP,PPP6R2,NOS1AP,C2CD2L,EFNB3,EIF4G2,SORBS3,C1orf61,AFF2,GPR153,GRM1,ATXN2L,IL6ST,MEF2C,NFYA,NNAT,RETREG1,SAMD9,RIPOR1,TMEM231,RAB3A,RAB3IL1,RGS10,KCTD17,PAQR6,EPN2,WDTC1,LHPP,CLSTN2,PLCB1,ARC,SMG6,KIAA0930,TK2" Drug 1415_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADORA3,PLA2G6,ALCAM,ATP2B1,HIP1R,ENTPD6,SLC4A7,SOCS5,RUBCN,TM9SF4,DDX46,FEM1B,EFNB3,ABI2,KCTD3,EPB41L2,ERCC2,DENND4A,VPS26C,EZH1,SEC23B,TRMO,STAU2,TRAF3IP2,DIDO1,NXPH3,KTN1,LAMP2,MBNL1,NFYA,PIK3R1,STRN3,LRP12,PPM1B,PTPA,CNNM2,RDX,RFX5,SATB1,SFPQ,CHD9,SPART,EPB41L3,NXT2,CBX5,RBFOX2,TPD52,MPPE1" Drug 1748_UP Ajmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "AMT,PKP4,ARNTL,ATP2A2,SLC24A2,IQCK,AKAP6,SEC31B,GIT2,EFNB3,FCGRT,CAMSAP1,PCYOX1,SMC2,ZMYND11,ERAP1,TMEM8B,KCNMB4,NR3C1,NXPH3,LSS,MIA2,NACA,NCAM1,SLC11A2,PDE4B,CCSER2,GPSM2,LRP12,MBOAT7,SAMD9,GON4L,RGS12,SEC61A2,FBXW7,AMBRA1,ZKSCAN3,EMC1,ZMAT3,TK2,PARD3,WBP2,UCHL1,VSNL1,REEP1,WNK1,NUP214,RNF170" Drug 6224_DN Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ALAD,AMPD2,PKP4,CASK,ARHGEF7,KRIT1,SCARB1,ZMYM4,NMT2,NCOR1,SOCS5,DCAF8,INTS1,GIT2,PARD6A,NR1D2,EPB41L1,SEMA4D,GPR19,AGBL5,DIPK1A,JAK2,MAP4,NFYA,NUCB1,PPP3CC,PPP5C,MAPK3,C1orf109,RAB3IL1,FOXRED2,CHD9,SCMH1,ZKSCAN3,SPATA7,ZSWIM8,UHRF1BP1L,POGZ,FCHO1,SUPT5H,ANKRD28,MTCL1,FBXW11,TIAM1,KAT6B,VAV1,FTSJ1,FIP1L1" Drug 2159_DN Sulfabenzamide [127-71-9]; Down 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ACTN2,AP2A2,RIPK1,ADAM15,BMP7,C5,CFAP410,CACNB2,USP2,RAB33A,PLAA,ZNF337,DGKG,CTIF,TRAPPC9,DTNB,E2F5,ING4,RASGRP2,PRKAG2,AFF2,ZNF44,ZMYND11,SRCAP,GIT1,CCSER2,PLTP,POU6F1,MINDY2,PTCH1,ZNF821,SH3BP2,EPN2,FAM214B,SLC11A1,SNCA,IZUMO4,UNC5B,FCHO1,NSD1,CHST8,TMOD1,TNS1,TRPS1,ZMYND8,LAMP5,GDPD5,PARP11" Drug 4977_DN SR-95639A [115767-94-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG3,PLA2G6,ALCAM,ANK3,DGKD,APP,RGS20,CA12,RCBTB2,VAX2,AKAP7,IQCK,FEZ1,PDE4DIP,DRD1,DTNA,TOM1,EDNRA,SORBS3,MRNIP,RRAGB,KIAA1109,TDRKH,KCNJ3,VWA5A,ZNF862,PTHLH,RIPOR1,ZDHHC14,RGS10,ZNF821,SLC6A8,SIRT2,RBM34,WDTC1,KDM4C,ROBO3,TRIM2,ARHGEF12,DICER1,CHST8,TPM1,CDK20,TRIO,RUNDC3B,LMF1,ZIC3,SSPN" Drug 5413_DN Methiothepin maleate [19728-88-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,C1QTNF3,SEMA6A,CDC42BPA,APC,APLP1,ALDH7A1,C5,TAOK2,ZFYVE9,CLU,CNTNAP2,DOCK4,TBC1D5,GIT2,ATN1,MAMLD1,SORBS3,EPB41L1,KAT8,SEMA4D,OGA,SPACA9,IGSF1,KHK,IPO5,VWA5A,KITLG,NF1,RETREG1,NLE1,STRN3,MBOAT7,PRKAR1B,RAB3IL1,MAPK12,UNC5B,ST5,VPS13A,PLCB1,KAZN,TCF7L2,PSD3,ARHGEF12,TNS2,AP4E1,EVI5,GDPD5" Drug 401_DN LY294002; Down 200; 10uM; ssMCF7; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RBM10,BRAP,APBA2,CDK10,ARNTL,BRINP2,HIP1R,IFFO1,AATK,CSNK1E,GAPVD1,DBN1,CALCRL,COQ7,FGFR3,CAP2,CAMKK2,ATP2C1,GNAO1,GPR19,RNFT2,SLC2A6,ARHGAP19,BRINP3,ITPKB,L1CAM,MAPT,MBD1,ADAM22,NRGN,MBOAT7,FSD1,NKAIN1,FOXRED2,ATXN2,ITSN1,KBTBD4,SNCB,ZCCHC24,EMC1,NXT2,SEPT8,NACC2,TMPO,TNS1,WIPF1,SLC13A3,GDPD5" Drug 3012_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ABAT,C3orf14,APBB2,ATP2B2,CADM3,FUBP1,MTMR3,THSD7A,CDC42,SOCS6,LHX2,ABCG2,DNAJB5,ARHGEF10,CHD5,TM9SF4,DYRK1A,COQ7,RASGRP2,DLC1,GABRA4,GNAL,GNAS,LILRA2,PADI2,MAP4,MAPT,MYBPC1,PHKG1,PLP1,CNTLN,PTCH1,ANKRD6,EPN2,MAPKBP1,ZNF415,ZCCHC24,SPTAN1,RAP1GAP2,NCDN,ATP11A,WSCD1,TCF7L2,PCDHGB6,TRO,OSBP2,LAT2,KCNK12" Drug 2754_UP Dacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,APLP1,CALB1,CDH10,RCBTB2,FOXN3,LHX2,PHF14,ARHGEF4,SEC14L5,TMCC2,DTNB,EDIL3,EDNRA,PLXNC1,EIF4G2,DMTN,ETV1,C1orf61,OGA,GABRG2,POLL,GRIK5,GSN,IL6R,KIT,VWA5A,MAP4,PDPK1,TMOD2,ELOVL2,FAM184A,KCTD17,PKNOX2,SLN,ZCCHC24,HECW1,IQSEC2,CAMTA2,PHLDB1,NSFL1C,JMJD6,VAMP1,KAZN,TBCEL,CRTC1,DICER1,SLC17A6" Drug 252_DN celecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,OGT,GAS7,APP,SLC4A4,HIP1R,CD86,CHGA,LHX2,CLU,SMARCAL1,CTIF,DRP2,DTNB,EIF4G2,F3,GAD2,DISC1,NR3C1,BTN2A1,PTPRT,C2orf72,IGF1,KCNJ5,LAMP2,STMN1,LIMS1,NF1,NPR2,STRN3,PPP2R2B,PPP2R5C,MAPK8,PTHLH,KLHDC8A,ROBO1,SATB1,ATXN2,ITSN1,FNDC3A,SPART,SSTR2,PRRC2C,ANKRD12,SEZ6L,PRMT8,UGT8,ZNF23" Drug 2392_DN Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,PLA2G6,ALK,MRTFA,CDC42BPA,APP,MARCH3,NCOA1,SYNJ2,CFAP410,CAPN3,CAST,KRIT1,IQCK,SH2B1,TBC1D5,MAML1,CTIF,SGSM2,TRAPPC9,TSPAN5,SORBS3,FCGRT,ZNF589,FHL1,SRCAP,MAP4K5,ELOVL5,LIG4,MAP4,RETREG1,ST8SIA5,FAM184A,ZNF493,FBXW7,ZNF671,MAP6D1,NUBPL,FCHO1,PJA1,EXOC7,TBL1X,TCF7L2,HIF3A,ZMAT3,TLR4,KAT6B,PIK3R5" Drug 6576_DN Prostaglandin E1; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SLC12A5,KIAA1324,LTBP4,APBA2,EPB41L5,APOC1,MARCH3,MARK4,KIF1A,BCL7A,CFLAR,CACNA1I,CHRNB2,VAX2,SLC4A7,DTNA,DTNB,EPB41L2,F3,F5,SRCAP,GLS,GNG4,GPER1,GRB10,GRM1,INPP5B,ITIH2,VWA5A,MAN2A2,NF1,NLE1,PLTP,EMID1,FOXRED2,SH3BP2,PEX26,COA1,ZCCHC24,EMC1,MAPK8IP3,EXOC7,PDLIM2,KIAA0930,TCF7L2,PARD3,PLPPR2,PRDM2" Drug 1913_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ARID1A,BRAP,BARD1,CHRNB2,ZFYVE9,TMEM184B,IQCK,HINFP,NCOR1,AATK,SOCS5,DZIP3,SEZ6L2,SORBS3,DMTN,ERCC2,FECH,EVL,PDLIM5,STAG2,GAD1,MALT1,CACFD1,BTN2A1,HNMT,PTHLH,ROGDI,RNF220,MYH14,SH3BP2,SH3GL3,SMTN,FAM214B,ELMO2,LIMCH1,SON,WDTC1,PEG10,ATP10B,CAMTA2,POGZ,GSE1,VAMP1,EXOC7,TBL1X,ZNF189,PRDM2,PARP6" Drug 665_UP "estradiol, USP; Up 200; 0.01uM; PC3; HG-U133A" Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "APBB2,SEMA4G,EIF4G3,STX16,NRP2,BMP7,ADGRG1,CNOT8,FAM189A2,TMEM184B,ARHGEF6,NCOR2,INTS1,SPATA2,G3BP2,DRP2,MBNL2,ZNF589,RUNDC3A,CACFD1,KIF3A,SLC2A6,MAN1B1,HMGCR,KCNN1,MAN2A2,MYO6,CLDN11,MED1,PTH1R,ZSCAN32,RGS3,RNASE1,PAQR6,SGK1,RCOR3,TSNAXIP1,SPART,SEMA4A,PHF24,TMPRSS5,TUB,VAV2,ZNF142,WNK1,EVI5,SLC17A7,PDSS2" Drug 5110_UP Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "PLA2G6,GAS7,SLC4A4,FOXN3,CHN2,STOML1,DNAJB5,VCAN,ABCC9,IGSF6,FGFR1,DISC1,LYVE1,HPGDS,GPM6B,GRM7,GRM8,BACH2,ITIH2,KCNA2,AFDN,NOS1,NOVA2,NTRK2,NTRK3,ABCB1,RETREG1,NECAB2,PPP5C,PTPRB,PTPRH,TMEM231,KHDRBS2,SLC6A15,RPS6KA2,S100B,ZNF821,SLC8A1,SAMSN1,MAPK8IP3,TACR1,PHF24,TK2,TLL2,CABIN1,TPM2,VIPR2,NUP214" Drug 3045_UP Hymecromone [90-33-5]; Up 200; 22.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "PLA2G6,ADGRF5,CDC42BPA,RGS20,ALDH4A1,RGS9,CFAP410,CALB2,USP2,CRLF1,SUSD5,CNTNAP2,SPOCK3,EDN3,EPB41,ZNF391,CORO2B,FLT1,SEPT9,NEU3,ZNF276,PCLO,RAPGEF4,GRIK1,GRIK5,WIF1,RASSF8,HLF,HTR5A,C2orf72,LSAMP,MAP2,MYH3,NF1,PDE4D,BCAS3,TTLL7,ZFP2,ASAP3,SMTN,SLC12A4,SLCO1A2,TCF7L2,PCDHGB6,DOCK9,TK2,SLC26A10,PMEPA1" Drug 4991_DN Glipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG3,NME5,OGT,PPFIA1,APP,SHROOM2,CAPRIN2,BCL7A,CFLAR,BTRC,MAGI1,QKI,CHD1L,ENTPD4,NCOR1,PDE4DIP,PARD6A,SGSM2,DTNA,TOM1,FCF1,EPB41L1,ACSL4,FER,SRCAP,ARFIP1,NR3C1,MAN2A2,MBP,CNOT4,NUMA1,RETREG1,PRKAB2,TMEM231,RAB3A,FAM184A,ROM1,PPP4R3A,LIMCH1,ZHX3,SS18,TTBK2,TMPO,VAV2,XRCC4,ZNF74,SMIM8,RNF146" Drug 6812_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RALGAPA1,ADRA1D,ATP6V0A1,GYG2,CRLF1,CHM,AKAP7,CSF1,CSF1R,CTNND2,RIMS2,PARD6A,MED12,DSCAM,TNK2,FHL1,FOXG1,SEMA4D,SRCAP,GLS,GNG4,GPR19,JAK2,KIF5C,MAP4,KITLG,GIT1,NUMA1,RETREG1,MED1,PPP5C,MAPK7,WDR25,ZSCAN32,RGS10,NEK11,SLC9A5,ZCCHC24,EMC1,ARHGAP26,CDK19,TROVE2,CEP68,ARHGEF9,IQCE,SLC44A1,ZKSCAN5,EPM2A" Drug 6297_DN Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "RBM10,BRAP,PPFIA3,APP,ZBTB10,CFLAR,SOCS6,ZFYVE9,VCAN,FAM169A,SLITRK5,PPP6R2,ZNF337,DLG3,DYNC1I1,RCAN1,OPTN,SUGP2,STX2,DENND4A,RACK1,PRRC2B,GPM6B,HNMT,MAP4,MEIS1,NEK1,PIK3R1,PLCD1,FA2H,WBP1L,RAB5B,SH3TC2,GAL3ST4,FAM102A,SLC1A3,KDM4D,SMARCA4,WDTC1,KDM4C,BEX1,ZBTB43,JMJD6,PSD3,ZMAT3,XRCC4,MAP3K12,PCBP4" Drug 6043_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,ABHD6,ADRA1D,MRTFA,PPFIA3,ARRB1,ALDH4A1,SYNJ2,USP2,ARHGEF2,SEPT7,FOXN3,QKI,HOMER3,NECTIN3,HINFP,CSF1,FAM169A,RASSF2,RABGAP1L,RCAN1,EFNA3,KAT8,FGFR1,ANKFY1,OGA,TRAF3IP2,GNG4,TDRKH,KCNF1,MAP4,ZNF862,NF1,RAB3IL1,ZFHX4,TRAPPC13,SUPT20H,ANKRD6,SLC6A8,ZHX3,KDM4C,PHLDB1,KIAA0930,TRIM2,PCDHA5,TMOD1,VGF,MPPE1" Drug 1503_DN Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG3,APOC1,CDK10,ARRB1,ARRB2,KIF1A,BTRC,CACNB2,CAMK2B,B4GALT6,SH2B1,CSF1R,HP1BP3,SLC12A6,DSCAM,DTNA,HIPK3,ING4,PCOLCE2,CDKL3,EZH1,INPP5K,GNG4,IL6ST,JAK2,MAP4,SCAMP5,ADAM22,NDUFA5,NF1,POLG,PRPH,PEX5,GSTCD,ITSN1,FNDC3A,BTBD7,KDM4B,EMC1,ZNF423,CDK19,ZBTB43,NCDN,SYT1,ATP11A,TRIO,TRPC1,HIRA" Drug 6865_DN SC-560; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,KIAA1324,MRTFA,APBB1,APC,CDK10,SLC4A4,RGS11,SCAPER,CFAP410,CDC42,ARHGAP33,NRXN3,CNTFR,AKAP7,AATK,SMG7,ACOT8,ST8SIA3,CELSR3,MBNL2,EIF5,ING4,MRNIP,ERCC2,TUBB4A,DCTN2,CGREF1,ERAP1,GRM7,KCNJ4,NPR2,CDK14,PTPRE,CCDC40,RAD52,ZNF671,CSRNP3,SH3BGR,SPTAN1,NCDN,CEP68,MCF2L,THRA,TIMP4,CDK20,ZMYND8,PARP6" Drug 5524_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SRPX,APBB2,MARK4,CFLAR,SYNJ2,CACNA1D,SLC25A14,MICAL2,SIPA1L1,SOCS5,PDE4DIP,TM9SF4,GIT2,SPATA2,SGSM2,CDON,MAMLD1,EFNA3,SORBS3,ERBB2,DLC1,FHL1,TRAF3IP2,GAD1,AHDC1,TDRKH,KCNJ3,LMO2,NF1,OCRL,LRP12,MAPK8,SUSD4,CLIP1,ITSN1,FERMT1,FUZ,SCMH1,BTBD7,ZCCHC24,ASTN2,TCF7,SLC44A1,KCTD2,PARD3,CADM1,PLPPR2,MPPE1" Drug 3433_UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADD2,NME5,MRTFA,DOC2A,AMPD3,APBB2,PDE8B,RASL11B,SLC4A4,SCAPER,CAMK2G,CDH8,ABI3BP,EDRF1,DAPK3,DRD1,RCAN1,EDN1,EDNRA,MTSS1L,SCML2,ALDH1L1,GPER1,IPO5,KITLG,MMP16,POLG,MINDY2,PRKAR1B,PTHLH,FAM120C,PEX5,RAB3IL1,ZDHHC14,KLHDC8A,WLS,ASAP3,FNDC3A,KAZN,EXOC7,CRTC1,TK2,VGF,VIPR2,SPHK2,WNK1,MVB12B,AP3B2" Drug 342_UP "novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "CDC42BPA,AZGP1,CDH18,CNOT8,JAM2,CNTFR,ENTPD4,HINFP,SEC14L5,C2CD2L,EFNB3,ELAVL4,KCNMB2,F5,BAIAP2,SEC23B,NSG1,GJB1,FERMT2,GRIK5,PTGDR2,KCNQ3,MAN2A2,MAPT,NAP1L1,NF1,NPPA,PDE4B,GPR173,LRRN3,MAPK10,RMI1,SEMA6D,SELL,SH3BP2,SLA,SLC12A2,SLC20A2,ZSWIM8,NMNAT2,ZBTB43,TRIM2,CLASP1,PHF24,FLRT1,ZNF24,PRDM2,SLC17A7" Drug 1775_UP Hydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "AGT,PLA2G6,SPARCL1,PPFIA1,APOC1,SEMA4G,ARRB2,MARK4,CACNA1I,OSGIN2,P2RX6,RAB26,AATK,ZNF804A,DNM2,EFNB3,SUGP2,BSCL2,ELN,EFS,FHL1,SEMA4D,CRCP,GLS,TJAP1,KCNH2,NOS1,NRGN,OGDH,POLG,PRPSAP2,MYH14,RXRA,ATXN7,EPN2,INTS9,TNIK,FNBP1,ZHX3,UNC5B,DBNDD2,TAC3,DDHD2,TCF4,TNS1,MPPE1,MARCH8,SMIM8" Drug 6459_DN S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASIC1,SEMA6A,AMH,CDC42BPA,FAM131A,CDK10,PLA2G4C,ATM,LDLRAD4,BTRC,B4GALT6,RAB28,ENTPD4,GREB1,NOS1AP,EFNB3,EGFR,SORBS3,LRRC23,OGA,DISC1,HNMT,HSD17B1,KCNH2,KHK,ODF2,PRODH,TMEM104,FAM184A,RGS3,WLS,EPN2,FAM214B,SLC20A2,LIMCH1,EMC1,IQSEC2,LHPP,POGZ,MAPK8IP3,ARC,TMEM121,SLC44A1,XRCC4,SYNC,MAP3K12,EVI5,MPPE1" Drug 436_DN HA-1077 dihydrochloride; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "MTUS1,GAS7,ZSCAN18,OSGIN2,HIP1R,SEPT7,NRXN1,NIPBL,NCOR2,CNIH3,C2CD2L,FAM13A,F5,FKTN,TESK2,BAIAP2,HPCAL4,SEPT9,GLYR1,GLS,ZNF638,GRIK5,NR3C1,SOX21,ICA1,KCNJ5,KTN1,LAMP2,MAPT,MMP17,NACA,NF1,NTRK3,OPCML,NLE1,NUDT11,ATXN2,CHD9,SLC6A9,FAIM2,DOK5,DBNDD2,VAMP1,PLCB1,IQCE,DMXL2,METTL3,UCHL1" Drug 6453_DN Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SEMA6A,TRMT9B,AMPD3,CDK10,PLA2G4C,MARK4,BAIAP3,CACNA1D,ENTPD4,SH2B1,MICAL2,GIT2,HP1BP3,EGFR,PLXNC1,COQ7,DMTN,FHL1,CNTRL,CACFD1,IPO5,LMO2,MAP4,LYRM9,NELL2,NFYA,NPR2,ODF2,P2RY1,PLXNB1,PRODH,PTN,ZSCAN32,RAB3IL1,KHDRBS2,ZNF821,BCAN,ZHX3,EMC1,LHPP,ARHGEF9,ARC,TCF7,HEY1,RBFOX2,LMF1,SYNC,URM1" Drug 3814_UP Guaifenesin [93-14-1]; Up 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "LTBP4,FGD2,AQP4,ATP2B2,CHRM4,TAOK2,STOML1,HAPLN1,DGKG,TRAPPC9,ATN1,DTNB,CALCRL,PIPOX,CACNG3,FGFR3,FLT1,EFCAB2,DKK3,SIGLEC8,DISC1,ALDH1L1,RAB30,LILRB4,RAPGEF4,ATXN2L,ICA1,KCNF1,MARK1,KITLG,AFDN,CD200,MYT1,NELL2,NPTX2,GPR85,PNMA3,RET,RGS12,RORB,EMID1,TRIM46,PKNOX2,SPTB,SEMA4A,THRA,SPHK2,HRASLS" Drug 1838_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ACTN2,NDRG2,ALAD,CDC42BPA,PDXK,ATP1A3,SYNJ1,CBFA2T2,CDC42,ZMYM4,CLCN4,TPP1,IQCK,DAPK3,DSCAM,EFNA3,PLXNC1,KCNMB2,PIPOX,FLNC,AHDC1,CACFD1,KCND3,KCNN1,MAP4,NEFH,CNOT4,PBX1,PIK3R1,PTN,PEX5,RIPOR1,MYH14,TCP11L1,PLPPR3,FUZ,SLC6A8,ARHGEF40,SLC12A2,CDK19,RBM26,TROVE2,ADGRL3,TCF7L2,PARD3,TRPS1,CLIP2,SPHK2" Drug 6788_UP Sulfaquinoxaline sodium salt [967-80-6]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "SPARCL1,KCNAB2,PRX,DNAH17,BAIAP3,CACNA1D,EPS15L1,QKI,PPP6R2,RASSF2,JAKMIP2,DMPK,TRAPPC9,EDNRB,MBNL2,AGAP2,RND1,GLYR1,GRIK5,GRIN1,ITIH2,KCNMA1,IPO5,LIG4,MAN2A2,KITLG,MPP2,ZNF862,NPTX1,PDE4D,EPN1,MAPK8,RGS10,RGS12,RNASE1,SUPT20H,SH3BP2,ASAP3,CNKSR2,INKA2,STX1A,POPDC3,TBCEL,PSD3,TK2,FAM155A,UCHL1,KCNK12" Drug 333_UP diclofenac sodium; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADORA2A,KIAA1324,DOC2A,APBB1,GAS7,LGR5,KIF1A,CCKBR,RAB28,NRXN1,CLTB,LY86,NIPBL,ARHGEF6,IFFO1,SH2B1,SIPA1L1,NCAN,FAM131B,MFAP3L,DLG3,SUGP2,BSCL2,ERBB2,EFS,F5,MALT1,GPR12,GRIK5,GRM7,KCND3,MBP,SETD4,OMG,CDK18,PIK3CD,MED1,PTPRD,RFX3,MAP6D1,KIF16B,SLC1A7,KBTBD4,SLC12A4,SST,SYN1,TACR1,AHCYL2" Drug 2815_DN Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "AMPD3,CDC42BPA,GAS7,APOC1,CDK10,ARHGDIG,MARK4,CFAP410,CACNA1D,LHX2,DNAJB5,SULT4A1,CNTN1,CSNK1E,SIPA1L1,JAKMIP2,DTNA,SORBS3,ENO2,LRRC23,GPR153,CSPG5,HBS1L,DISC1,AHDC1,GLYR1,NR3C1,HNMT,DHX35,TJAP1,SMAD1,MDM4,MITF,MOBP,MX1,NEK1,SMIM7,POLG,MINDY2,PRPH,ELOVL2,CEP97,RAD52,SH3BP2,FAM214B,R3HDM1,RBFOX2,KCNK12" Drug 4579_DN Tiabendazole [148-79-8]; Down 200; 19.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "MTUS1,MRTFA,PKP4,ASPH,ADGRB2,FOXN3,CLCN4,TPP1,COL9A2,NCOR2,ARHGEF10,TOM1,MAMLD1,AASS,ETV1,CINP,DLL3,FYB1,ZMYND11,C1QL1,SLC2A6,MAP4K5,INPP5B,ITPKA,KIF2A,MDFI,ZNF862,CNOT4,PDE1C,GRAMD1C,PROX1,CNNM2,TMEM231,RAB5B,FAM184A,MYH14,ROM1,SCN8A,ASAP3,FBXO11,FNDC3A,ZNF334,SLC20A2,ARHGAP26,SYT1,SZT2,UGT8,WNK1" Drug 908_UP 5140203; Up 200; 15uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "BRAP,ANK3,APBA2,APP,RASL11B,STX16,CFLAR,C5,ARHGEF2,CDH2,LRRFIP1,MAGI1,VAX2,FEZ1,EDRF1,RCAN1,DTNA,DUSP9,SIDT2,EIF4G2,IRAK4,F8,PDLIM5,HTATSF1,GPD2,NUDT21,CNTRL,SPACA9,INPP5B,LIG4,MBD1,MDM4,MITF,SETD4,MINDY2,RNASEL,FNDC3A,SLC6A8,BTBD7,ZCCHC24,AP4E1,RBFOX2,MICAL1,VLDLR,XRCC4,WNK1,PHTF2,SSPN" Drug 2106_UP Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,PLA2G6,MRTFA,DOC2A,APP,SEMA4G,MTMR3,BTRC,CDC42,LARGE1,DNAJB5,IQCK,CRMP1,TM9SF4,CTIF,ATN1,ANKMY1,EZH1,KAT8,FGFR1,FYN,ATP8A2,GLYR1,TDRKH,CACFD1,INPP5B,MGAT3,MITF,CNOT4,NPPA,PCDH9,BCAS3,PTN,PEX5,RIPOR1,SUSD4,RGS10,NEK11,STUM,AMBRA1,ZHX3,COLGALT2,MAPK8IP3,ARC,WSCD1,RIMBP2,VGF,MAP3K12" Drug 2905_UP Cyclopenthiazide [742-20-1]; Up 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ACTN2,BIN1,CDC14B,ATP6V0A1,CACNG1,CLGN,CLCN4,STOML1,CNTN1,SPOCK2,DTNA,ST8SIA3,FAM13A,LPAR6,MRNIP,RRAGB,SH3YL1,SEC24B,GAA,RAB40B,KIFC3,MAP4,TM6SF1,AFF1,ADAM22,NCAM1,NTRK3,NLE1,SMOX,SLC25A23,LRP12,PPARA,LRRN3,CEP41,BCAS3,PTAFR,RGS10,TCP11L1,SH3BP2,SLC1A7,ARHGAP26,NPAS3,TBCEL,TCF7L2,SZT2,SLC13A3,ZFP37,PRDM10" Drug 5082_UP Isometheptene mucate; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ASPHD1,MRTFA,ADGRB1,BAIAP3,LDLRAD4,CDH10,CACNA2D2,RAB26,AKAP6,SUSD5,FAM131B,ECM2,FRY,COQ7,CEND1,CORO2B,EFCAB2,PRELID3A,GATM,RUNDC3A,GNAO1,SPACA9,HRH3,KCNF1,KCNJ5,MAPT,MATN3,TREM2,PBX1,PROX1,PID1,RAD52,RGR,RGS10,MYH14,CNKSR2,RIMS1,SNAP25,SNCA,HECW1,DDN,TACR1,MCF2L,KIAA1107,SYNE1,R3HDM1,CHST5,SEMA3B" Drug 7238_DN Leflunomide [75706-12-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "MRTFA,CDC42BPA,EPB41L5,CDC14B,ALDH4A1,BCL7A,CFLAR,CACNA1D,SCARB1,HOMER3,ABCG1,LRIG1,SOCS5,FAM169A,GPRASP1,GIT2,DBN1,PHC2,SIDT2,EZH1,EFEMP1,FOXG1,DPYSL4,CGREF1,AHDC1,COPS8,HNMT,INPP5B,KCNJ3,KIF5C,IPO5,MITF,PDE4A,RC3H2,PRKAR1B,SAMD9,NKAIN1,GTDC1,SFPQ,SLC1A7,PPP4R3A,SMTN,FNBP1,CAMTA2,ASTN2,MCF2L,SATB2,BEX4" Drug 1163_UP 2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "APP,MARK4,NCOA1,N4BP2L1,ST3GAL5,CAMK2G,MAP7,CNOT8,NMT2,AKAP6,SLC4A7,TBC1D5,RUSC2,FCF1,TNK2,EIF1,RASGRP2,RABEPK,ECSIT,F5,FOXG1,HTATSF1,LPAR4,MAP4,OLR1,PENK,NLE1,SLC25A23,POU3F2,PPP5C,PTPRB,PTPRN2,TMEM231,SUSD4,ITSN1,PALLD,KDM4C,UNC5B,CDK19,PLCB1,SIN3B,TCF7L2,FLRT2,VIPR2,MAP3K12,KCNAB1,UBE3B,PHTF2" Drug 7526_DN 15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NME5,APOC1,PPFIA3,NCOA1,ARHGEF1,CDC42,ARHGAP22,CLTB,RAB26,NRG2,TENM4,CNTNAP2,ATN1,TUBD1,EZH1,SORBS1,USP19,CRCP,GLI2,GLRB,IL12A,INPP5B,MMP17,ZNF862,NPR2,PALM,PTPRN2,SH3TC2,RAP1GAP,GAL3ST4,MRAS,SCG5,SLC4A3,KDM4B,WDTC1,SPTAN1,FCHO1,ARHGEF9,SYT1,ROBO3,IQCE,CHST5,HIRA,PDIA2,WRN,ZNF74,NDRG4,HPS4" Drug 5479_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NLGN4X,BIN1,FAM131A,SLC4A4,ATP2B2,CADM3,SYNJ1,CFAP410,INA,FOXN3,CLCN4,WHRN,COL9A3,ATRNL1,SLITRK5,RIPOR2,ARHGAP24,KBTBD11,NCALD,IGSF6,OLFM1,PRELID3A,CNTRL,NR3C1,IPO5,MMP16,NELL2,NTRK2,KCNK10,WDR25,BEND5,ZDHHC14,KLHDC8A,ROBO1,SLC2A5,COA1,PDZD2,IQSEC2,SYT5,EXOC7,CRTC1,THRA,HEY1,TNS1,PIK3R5,LMF1,WIPF1,ZIC3" Drug 2849_UP Tetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "NDRG2,ADCY6,AP2A2,KIAA1324,C1QTNF3,CDC42BPA,APAF1,APBB2,BCAS1,ARHGDIG,PDE8B,ALDH4A1,ALDH7A1,KYAT1,CSF1,FEZ1,PPP6R2,DOCK4,SPOCK2,DNM2,SORBS3,ELN,CDKL3,SCARA3,GABRA5,GNAO1,TDRKH,ELOVL5,VWA5A,MMP16,MSI1,CNOT4,PC,PPARA,PPP2R2B,PRKAR1B,MAPK10,PTN,RAD52,CRTAC1,CARF,SLN,SOX3,ZCCHC24,ROBO3,TK2,REEP1,GDPD5" Drug 2176_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "APAF1,APC,APP,ASPH,KIF1A,ADAM15,MPDZ,SH2B1,CSF1,PPP1R16B,ZNF337,TSPAN5,HIPK3,FEM1B,SIDT2,FAM13A,PLXNC1,ZNF589,CAMSAP1,FHL1,NBEA,GNG4,GRIK5,LSS,MDM4,CCSER2,PLCD1,PLP1,ZSCAN32,RAB3A,ZNF493,MAPK12,SBF1,TMCC1,IZUMO4,SPTAN1,ZBTB43,SS18,JMJD6,EXOC7,TGFBR3,SLC44A1,KAT6B,TPM3,VIPR2,MKRN3,EVI5,GDPD5" Drug 5284_UP Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "ADCY6,AGT,ALCAM,APC,BCAS1,MARK4,ASPH,NCOA1,ALDH4A1,SYNJ2,SCAPER,BTRC,CAMK2B,NEURL1,PDE4DIP,SPOCK2,DSCAM,EIF4G2,KIAA1109,BAIAP2,GABRA2,AHDC1,GRIK5,BTN2A1,PTGDR2,IL6R,MAP4,MDFI,PTN,NKAIN1,ZNF821,SH3BP2,FNDC3A,SYBU,SLC1A7,PREX2,SLC9A5,ZKSCAN3,SNCA,FCHO1,INKA2,CEP68,TMEM121,CDK20,TRIO,ZMYND8,PLPPR2,KLC2" Drug 3170_DN Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.16E-03 1.00E+00 7.99E-03 9.09E-02 48 198 "TRMT9B,APOC1,SOCS6,FAM189A2,HOMER3,CRY2,ARHGEF10,SOCS5,RABGAP1L,FCF1,EFNA3,SUGP2,RGS17,ENO2,F3,DPYSL4,ZNF44,GALC,GRB10,HSD17B1,LMO2,NFYA,SLC11A2,PDE3B,PMP22,RAB3A,RAB5B,ZCWPW1,RGS12,EMID1,TRAPPC13,SLC1A7,KIF13A,KDM4B,THSD1,STX1A,VAMP1,TACC1,MTCL1,SEMA4A,IQCE,KIAA0930,TCF7L2,TNS2,PCDHA6,AHCYL2,WBP2,ZKSCAN5" Drug ctd:D008345 Manganese CTD 1.17E-03 1.00E+00 8.05E-03 9.16E-02 101 481 "ACHE,DSCAML1,AGT,APLP1,APP,AQP4,ARHGDIA,ATM,ATP1A3,MYOM1,CA8,CAMK2A,AKAP7,NRG2,CRYM,RGS6,ARHGEF4,SCRN1,HEPH,ABI2,ERCC2,PTK2B,ATP8A1,FCGR1A,PPP1R1B,OLFM1,FHL1,VTI1B,FOXO3,DACH2,STAU2,SDCBP2,GABRG2,GFAP,PPARGC1A,TNRC6A,GLUL,GPD1,MCHR1,GPER1,GPR34,GRIN1,ANKRD36BP1,FAM107A,GUCY1A1,GUCY1B1,ATOH8,HMGCR,IDH3A,IL12A,ITGA7,ITGAM,ITIH2,KCNJ3,KCNJ11,SFXN5,MBP,MID1,NFE2L2,NFIX,NOS1,NPPA,SLC11A2,OGDH,OGG1,ABCB1,FA2H,MAPK3,MAPK8,MAPK9,PTX3,RPE65,GLDN,LRRK2,SCN7A,SLC30A10,SLC1A2,SLC1A3,SIRT2,SLC12A2,SNCA,SCN3B,MYT1L,SPP1,SPTAN1,STOX1,VPS13A,SYN1,TACR1,PCDHA6,ATP13A2,TF,LEFTY2,TRPC3,UCHL1,LAT2,ZFP41,SLC38A1,EPM2A,AP3B2,SLC4A10" Drug CID000001210 "Tubocurarine,d" Stitch 1.17E-03 1.00E+00 8.05E-03 9.16E-02 22 72 "ACHE,BCHE,BSN,CHRM1,CHRNA4,CHRNB2,CNTN1,SNAP91,DMPK,MYOZ2,KCNMB4,GRIK1,KCNN1,KCNN2,KCNN3,ENPP2,RPS6KA2,SNRPN,TCEA1,TMPO,TUB,FTSJ1" Drug CID000000194 AC1L1IO7 Stitch 1.17E-03 1.00E+00 8.05E-03 9.16E-02 22 72 "ADORA1,ADORA2A,ADORA3,AMPD2,AMPD3,P2RX6,ENTPD2,LPAR6,GMPR2,LPAR4,NUDT21,MBP,P2RY13,NHLH1,P2RX7,P2RY1,ENPP2,APTX,PYGM,SARS,DDN,P2RY12" Drug 3340_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "TKTL1,NDRG2,NME5,KIAA1324,ARRB1,CACNG1,RAB33A,CRMP1,CSF1R,NOS1AP,HP1BP3,ATN1,EFNB3,SPEG,ZIC4,FGFR3,FYB1,FYN,GAP43,GNAO1,GNAS,GPR22,GRIK5,GRM7,ICA1,IL6R,KCNB1,KCND3,NF1,NNAT,PCDHGC3,PDE3B,SCN8A,RASA3,ASAP3,SLC1A2,SLC9A5,SOX10,DOK5,LMO3,TBL1X,WSCD1,DOCK9,VAV2,WIPF1,DNALI1,PAK5" Drug 7065_DN SC 19220; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "BRAP,C1QTNF1,KCNAB2,MARK4,ALDH4A1,MPDZ,ST3GAL5,CBFA2T2,RCBTB2,PLAA,WHRN,PDE4DIP,EDRF1,SIRPA,B3GAT3,SMG7,ETV1,KIAA1109,FGF1,DPYSL4,POMT1,DENND2A,GART,SRCAP,KLF12,KHK,PENK,VPS13C,GON4L,RAB3IL1,ROGDI,TRAPPC13,SUPT20H,FAM102A,DZIP1,PEX26,KBTBD4,KDM4C,RAP1GAP2,TCF4,TCF7L2,ZMAT3,MICAL1,NDRG4,MAP3K12,EMSY,ST7" Drug 5629_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "ARID1A,GAS7,PDE8B,MARK4,SYNJ2,GYG2,CACNA1I,SULT4A1,ABCG1,PDE4DIP,ARHGEF4,RIMS2,DCAF4,ARMCX2,MFAP3L,HP1BP3,SLC12A6,EFNB3,LRRC23,KIAA1109,HBS1L,GLYR1,RAB30,CACFD1,KPNA5,LYRM9,STRN3,MED1,GRAMD1C,SUPT20H,ANKRD6,SIRT2,BTBD7,COA1,ZHX3,ANKRD28,KIAA0930,CRTC1,CHST8,TMOD1,CDK20,TRIO,ZFP37,ZBTB14,SYNC,SLC17A7,SENP7" Drug 6485_DN Chrysin [480-40-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "MTUS1,CDC14B,MARCH3,KRIT1,LHX2,RAB28,AKAP12,FAM169A,GIT2,DBT,RABGAP1L,EXOG,PLEKHO1,STX2,FGFR3,BAIAP2,SYNCRIP,PDLIM5,MALT1,SLC2A6,HNMT,MAP4,PMP22,FA2H,PRKAR1B,PTCH1,RIPOR1,ITSN1,FERMT1,SHANK2,ELMO2,PDZRN3,ERC1,SPART,CLASP2,ELOVL4,JMJD6,MCF2L,ACTR6,BEX4,SSBP2,LMF1,ZIC1,REEP1,C12orf4,MARCH8,RNF170" Drug 2842_UP Tolazamide [1156-19-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "MTUS1,AK2,KCNAB2,GAS7,ATM,SLC2A11,CFLAR,BMP7,GYG2,CACNA1I,BTRC,CA4,CACNB2,KYAT1,SLIT2,SLC4A7,CSF1R,RIMS2,SIDT2,ERCC2,VPS26C,KIAA1109,FGFR1,BAIAP2,FAM49B,OGA,GLS,ADAMTS13,GRM1,IL6ST,KHK,MAP4,ADAM22,NF1,LRP12,SYNDIG1,SELL,LIMCH1,IQSEC2,MAPK8IP3,JMJD6,ATP11A,DMXL2,UBE3A,LMF1,WNK1,PHTF2" Drug 455_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "NDRG2,ADD3,AGT,ALCAM,GAS7,PDE8B,CA12,AP4M1,CNTFR,SH2B1,INTS1,EXOG,DRP2,SIDT2,EFNB3,MBNL2,EGR3,PLEKHA1,MRNIP,SCML2,FDFT1,NCKAP1,GART,RUNDC3A,HPGDS,ATXN2L,MAN2A2,AFF1,MX1,MYO6,NF1,NPPA,RGS3,TCP11L1,SEMA6D,ATXN2,AMBRA1,ELMO2,TMCC1,SON,COBL,TAL1,TCF7,WASHC4,FAM155A,SLC13A3,VPS35L" Drug 4067_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "MRTFA,DNAH17,NRP2,MYRF,ARHGAP22,DNAJB5,CNTFR,NRG2,NCOR2,MFAP3L,SMG7,CELSR3,AASS,STX2,ST3GAL6,ZNF44,ERAP1,TMEM8B,USP19,GPR19,GPER1,GUCY1A1,GUCY1B1,MAPT,NOVA2,ZSCAN32,RAB3IL1,SH3TC2,RGS4,PREX2,UNC5B,DDN,THSD1,CEP68,TBL1X,TRIM2,RPGRIP1L,PCDHA5,TRIO,HIRA,PLPPR2,VGF,MICAL1,XRCC4,EMSY,UBE3B,TIGD6" Drug 2833_DN Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "APC,CDK10,NUMB,SYNJ2,MTMR2,BTRC,CAMK2G,B4GALT6,RAB28,CLCN3,QKI,SLC4A8,DZIP3,TBC1D5,HP1BP3,SMG7,DSCAM,PDLIM5,CGREF1,HBS1L,SRCAP,GLYR1,CNTRL,MAP4,ADAM22,RETREG1,SLC25A23,STRN3,PKN2,PRPH,WDR25,ELOVL2,SLC25A36,SEC14L1,TRA2B,SYBU,SIRT2,USP33,ZCCHC24,ZBTB43,THSD1,ASTN2,TMPO,ZMYND8,VGF,ZNF45,MPPE1" Drug 1703_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "NDRG2,KIDINS220,ALCAM,SLC4A4,CDK5R1,RAB28,MFAP3L,KBTBD11,MBNL2,RGS17,HSD17B14,BAIAP2,IQCG,EFCAB2,CGREF1,TMEM8B,GPER1,ICA1,INPP5B,KCNK1,KCNMA1,KHK,MBP,NRCAM,NUMA1,RETREG1,PLCD1,ING3,SIDT1,ELOVL2,RAD52,GSTCD,SH3BP2,SLC22A4,ZCCHC24,ST5,EHBP1,SZT2,PSD3,ZNF34,TMPO,TRIO,RUNDC3B,XRCC4,WNK1,VPS35L,EPM2A" Drug 3850_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "ADORA1,NME5,BACH1,MTMR3,CAMK2B,CLGN,ADGRG1,CNTNAP2,FAM169A,ECE2,DAPK3,SPOCK2,DYRK1A,ING4,ERCC2,SPEG,CAMSAP1,CAMKK2,FUT9,GAD2,NEU3,SPIN1,GPER1,PCLO,GSN,KHK,LSS,KITLG,NUMA1,PTAFR,MARCH1,RGS12,RPS6KA2,BCAN,PPP4R3A,SLN,OGDHL,FAIM2,RBM34,TSNAXIP1,ZBTB43,POPDC3,SZT2,PIK3R5,SLC13A3,KCNAB1,KAT6A" Drug 4671_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "RALGAPA1,ARID1A,ADRB2,AGT,ANK3,PPFIA4,LGR5,ATP1A3,NRP2,CLCN4,ENTPD4,CRY2,ARHGEF10,ARHGAP24,KIAA0513,FBXL5,RHOBTB1,GABRA2,GBX2,C1QL1,MDFI,MID1,AFF1,PPARA,FAM120C,PTX3,TMEM231,ROM1,FOXRED2,ZNF821,PPP1R9A,FRMPD1,NLGN1,PEX26,TSNAXIP1,KDM4C,UNC5B,RBM26,DDN,PHLDB1,TK2,TNS1,WNT7A,EVI5,SCG2,NAV3,NAV2" Drug 4118_UP Gramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "AGT,AMPD3,ASTN1,B3GALT2,BAIAP3,RUNX1T1,CDH10,CHRNB2,C2CD2L,SPOCK3,DYRK1A,EFNB3,MTSS1L,ST3GAL6,DCTN2,SORBS1,FYN,GPR75,RAPGEF4,GSTM5,GUCY1B1,HPSE2,KCND3,KCNJ5,ADAM22,NF1,SAMD9,RAB3A,GSTCD,RASA3,SH3BP2,FRMPD1,SNCA,SOX10,ATP10B,SYT5,WSCD1,TF,TNS1,TPM2,TRPC1,PDIA2,FLRT1,WIPF1,ZIC3,DNALI1,PARP11" Drug 3322_DN Iohexol [66108-95-0]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.17E-03 1.00E+00 8.05E-03 9.16E-02 47 193 "ADORA2A,SEMA6A,ANK3,EPB41L5,ARNTL,SYNJ1,CA4,ARHGEF2,RCAN1,DTNA,FCF1,EFNA3,HSD17B14,FER,RUNDC3A,GLYR1,RAB30,GPER1,GRB10,TJAP1,KITLG,GIT1,NEK1,NF1,NFYA,NPTX1,PDE3B,STRN3,ZSCAN32,ATG16L1,ZNF493,RGS10,TCP11L1,FNDC3A,NXT2,STX1A,PLCB1,TRIM2,PSD3,TMOD1,TMPO,KAT6B,TRPC1,ZIC3,ZNF24,GDPD5,LAS1L" Drug CID000017429 FP-I Stitch 1.18E-03 1.00E+00 8.09E-03 9.21E-02 16 46 "SLC12A5,APBB1,ZFYVE9,EDN1,ATP8A2,GFAP,LYVE1,RBPJ,LAMP2,PDYN,PTHLH,ADHFE1,SYN1,SYN2,TBL1X,WIPF1" Drug CID000000109 cysteine sulfinic acid Stitch 1.18E-03 1.00E+00 8.09E-03 9.21E-02 16 46 "PRX,NFS1,CDO1,CTH,PLEKHM1,CDON,GAD1,GAD2,PCSK1N,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,SCRT2" Drug CID011819083 1 sulfonylurea Stitch 1.18E-03 1.00E+00 8.11E-03 9.23E-02 37 143 "APLP1,CACNA2D1,NGB,CAPN3,CLCN3,DBI,HEPH,ABCC5,ABCC9,GAD2,INPP5K,GCK,GPD1,GPD2,HBA1,HMX1,KCNA1,KCNA4,KCNA6,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNJ16,NEUROD1,PFKFB2,PFKFB3,PFKFB4,ABCB1,FTO,ENOX1,RIT2,SST,ABCC8,TCF7,NETO1" Drug 6195_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 8.12E-03 9.24E-02 46 188 "NDRG2,ADD2,MTUS1,APP,TAOK2,CLCN4,HOMER3,CPS1,C2CD2,MICAL2,VCAN,SLITRK5,CTH,RHOBTB1,KBTBD11,PCOLCE2,NCALD,DLC1,FOXG1,CAMKK2,FYB1,SEPT9,GART,SRCAP,GRB10,ATXN2L,ELOVL5,SMAD1,MAP4,NDUFA5,PTAFR,RAD52,RAP1GAP,GSTCD,LGR4,PLPPR3,ZNF821,SLC1A3,ZNF667,EMC1,DDN,CUX2,TNNT1,TNS1,CDK20,FLRT2" Drug 4296_UP Gossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 8.12E-03 9.24E-02 46 188 "PKP4,EPB41L5,AQP6,CDK10,CBS,ARHGEF2,LARGE1,STOML1,DNAJB5,CREB5,CTH,NR1D2,DTNA,MBNL2,ELN,ATP8A1,FGFR1,TBR1,ERAP1,RND1,FERMT2,GPR22,PADI2,IL6ST,MAP4,MDM4,PDE3B,PFKFB3,PFKFB4,LRP12,PRKAB2,VPS13C,ZSCAN32,PTX3,SLC25A36,CPEB3,DZIP1,SPTB,SSTR2,ARC,TCF4,RUNDC3B,CADM1,SLC13A3,MKRN3,EPM2A" Drug 5921_UP thioridazine hydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 8.12E-03 9.24E-02 46 188 "APAF1,CDK10,PPP4R4,SYNJ2,BTRC,CBS,MAGI1,LHX2,TPP1,QKI,PICK1,SLC4A7,PDE4DIP,CTH,HDAC9,RUSC2,RABGAP1L,ATN1,TOM1,OPTN,MBNL2,ELN,EZH1,EFEMP1,FGFR1,RND1,MAP2,ADAM22,NCF2,NFYA,OPCML,POU6F1,CNNM2,PNMA8A,GSTCD,ATXN1,FNBP1,ZHX3,TSPYL2,SYT1,ARHGEF12,CHST5,VLDLR,WNT7A,PMEPA1,PRDM2" Drug 2461_DN Iohexol [66108-95-0]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 8.12E-03 9.24E-02 46 188 "ABR,AK2,MRTFA,CDK10,CDK13,ATM,STX16,CFLAR,BTK,CD86,SCARB1,HOMER3,RUBCN,GIT2,DBT,DTNA,VPS26C,ZNF589,PDLIM5,FAM49B,ALDH1L1,TXNL4A,MSL3,IL6R,MAP4,PIK3CD,PLEC,ZNF426,PMS2,SNRK,RGS10,SLC25A36,RASA3,SMARCA4,ARHGAP26,RBM26,TROVE2,POGZ,ZC4H2,GANAB,KAZN,ZMYND8,HIRA,LAT2,NSD2,WNK1" Drug CID000004242 NSC-343257 Stitch 1.19E-03 1.00E+00 8.12E-03 9.24E-02 54 229 "AGT,APOC1,APOC2,APP,ATP1A1,ATP1A2,ATP1A3,ATP1B3,GPC2,B4GALT6,COG1,CLTC,SLC4A7,HAPLN1,VCAN,SDC3,HDAC4,SPOCK2,SPOCK3,NTM,SLC25A18,CALCRL,FCGRT,FOLR2,NPTN,DNER,NEU3,GHR,HMGCR,IGF1,LAMP2,SYT9,MTTP,NPPA,PDE1C,ABCB1,PLP1,PSD,PTHLH,PID1,ALG9,SMPD3,FNDC3A,ZNF365,SLC9A5,SHANK2,BDP1,APOM,NEU4,TF,TGFBR3,RBFOX2,PITPNB,HPS4" Drug CID005288622 AC1NRBT8 Stitch 1.19E-03 1.00E+00 8.13E-03 9.25E-02 9 19 "AGT,CLTA,APPL1,EDN1,EDNRA,FGF1,SEPHS1,TNNT1,AAAS" Drug CID000030768 etifoxine Stitch 1.19E-03 1.00E+00 8.13E-03 9.25E-02 9 19 "ATM,DBI,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PTCH1" Drug ctd:C071262 SK&F 82958 CTD 1.19E-03 1.00E+00 8.13E-03 9.25E-02 9 19 "ADCY2,ADCY5,ADCY6,ADCY8,DRD1,PPP1R1B,NOS1,PDYN,RYR1" Drug CID000031721 p-methoxyamphetamine Stitch 1.19E-03 1.00E+00 8.13E-03 9.25E-02 9 19 "ABR,CARS,E2F6,LOXL3,MAOB,PMP2,SEPT4,SOX10,ZEB1" Drug CID006438338 Volkensin Stitch 1.19E-03 1.00E+00 8.13E-03 9.25E-02 9 19 "ADORA1,CHRM1,CLU,DRD1,EEF1A2,FCGRT,GAD1,GAD2,HTR2A" Drug ctd:D010852 Picrotoxin CTD 1.19E-03 1.00E+00 8.16E-03 9.28E-02 27 95 "ADRA1B,ADRB2,ALAD,CALB1,CALB2,CCKBR,CHRM1,EDN1,EDN3,EDNRB,GABRA1,GABRA2,GABRB1,GABRB3,GABRG2,GAD1,GAD2,GPD1,KCNJ11,SMAD1,PDE4D,PFKP,PGAM2,SSTR2,ABCC8,ACSL6,TGFBR3" Drug CID000004008 manidipine Stitch 1.19E-03 1.00E+00 8.16E-03 9.28E-02 27 95 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CBFA2T2,CACNA2D2,EDN1,CACNG7,CACNG3,CACNG2,ACTL6B,HMGCR,MYH6,NPPA,OLR1,PKD1,RYR1,RYR3,TPCN2,ACTR6" Drug 1590_UP Betamethasone [378-44-9]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.19E-03 1.00E+00 8.17E-03 9.29E-02 45 183 "ADD2,ADORA3,AMT,APC,ARNTL,CA12,RCBTB2,AKAP7,PPP1R16B,FEM1B,FAM13A,EPB41L2,DENND4A,VPS26C,CEND1,F3,CAP2,CRCP,GLUL,IRAK3,MAN1B1,ITGA7,KCNH2,AFF1,MPP2,NTRK2,PLCD1,RETREG2,RDX,TMEM156,ATXN7,FNDC3A,SLA,SLC11A1,ELMO2,KDM4B,POGZ,SAMSN1,STAU1,KANK1,TCF7L2,FLRT2,VIPR2,WIPF1,ZBTB16" Drug 7088_DN pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.19E-03 1.00E+00 8.17E-03 9.29E-02 45 183 "ANK3,APBB2,APP,IL33,CBFA2T2,RCBTB2,RAB28,ZFYVE9,ABI3BP,HAPLN1,PDE4DIP,CTH,SMG7,G3BP2,DYNC1I1,RCAN1,APH1A,IRAK4,EPB41L2,ETV1,SPIN1,HTATSF1,GPR37,KCNMA1,MAP4,PIK3R1,PLEC,BCAS3,PTCH1,RPS6KA2,ZFP30,PEX26,RAB3GAP1,CDK19,PDLIM2,TRIM2,SYNE1,PSD3,AHCYL2,KAT6B,METTL3,SSBP2,HIRA,ZBTB38,MPPE1" Drug CID000038945 tocainide Stitch 1.20E-03 1.00E+00 8.20E-03 9.32E-02 12 30 "ASIC1,ANK2,ASIC3,ACOT7,KCNA4,KCND2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug 6047_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.20E-03 1.00E+00 8.22E-03 9.35E-02 44 178 "ALCAM,CFLAR,KRIT1,TAOK2,CLCN3,HOMER3,ARMC8,FEZ1,PDE4DIP,ZBTB24,RHOBTB1,ANKRD46,EIF5,EZH1,ARMCX1,TBC1D16,GPR19,JAK2,SETD4,PDCD2,PIK3R1,RFX5,MAP6D1,TRAPPC13,ZFP30,ITSN1,SYBU,PAAF1,ZNF365,ZKSCAN3,ZNF302,CEP68,KANK1,ZC3H4,ARHGEF9,ASTN2,FAM208A,CHST8,ZMYND8,ZIC1,ZNF23,MAP3K12,HPS4,ZNF248" Drug ctd:D013501 Surface-Active Agents CTD 1.21E-03 1.00E+00 8.26E-03 9.40E-02 40 158 "C1QTNF4,APP,ATP1B3,LDHD,NFS1,CDH2,L3MBTL4,ACBD5,NCAN,PHF14,DBT,PITPNC1,EBF1,GOLGA7,ARFIP1,KCNA2,NCAM1,NINJ2,DDR2,PAH,DUSP26,PKM,PACSIN1,FSD1,MAPK3,MTMR10,SLC25A36,KIRREL1,RPE65,SLC6A1,TNIK,MAPK8IP3,ADHFE1,STX1A,SF1,AGMO,FSTL5,MDH1B,MPPE1,CBLN2" Drug CID000003892 NSC339663 Stitch 1.21E-03 1.00E+00 8.29E-03 9.43E-02 58 250 "ACTN1,MRTFA,MYH7B,ARRB1,ARRB2,DYNLL1,SLC2A11,CBS,CDC42,MYL6B,CLTA,CLTC,DLG4,ABI2,SORBS3,TUBD1,EPHB1,TUBB3,TUBB4A,FER,ACTL6B,GAB1,TUBA8,RND1,TUBA1C,RAPGEF1,GSN,TUBB2B,AFDN,TAGLN3,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,PIK3R1,PLEC,MAPK3,MAPK4,MAPK7,PTK2,MYH14,RTKN,MYO18A,SMTN,SHANK2,SLC12A2,SNAP25,SYNE2,ARC,SYNE1,ACTR6,TPD52,TUBB1,ANKS1B,TUBA1A" Drug ctd:D002712 Chlorides CTD 1.23E-03 1.00E+00 8.37E-03 9.52E-02 15 42 "SLC12A5,ADRB2,SLC22A6,CLCN3,SLC12A6,GABRA1,GABRA2,GABRA4,GABRB3,GABRG2,IGF1,NPPA,SLC6A11,SLN,BEST1" Drug CID000009012 m262 Stitch 1.23E-03 1.00E+00 8.37E-03 9.52E-02 15 42 "API5,ASIC3,BAG4,DBT,EEF1A2,LNX1,KCNC1,KCNC2,KCNH2,KIT,KITLG,PDCD2,SLC20A2,LRRC4,NELFE" Drug CID000068930 5 beta-alphaxalone Stitch 1.23E-03 1.00E+00 8.37E-03 9.52E-02 15 42 "SNAP91,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,GRIK1,KCNJ3,KCNQ2,TPM3" Drug CID005289411 ST-8 Stitch 1.23E-03 1.00E+00 8.37E-03 9.52E-02 15 42 "CANX,AIFM1,SUMF2,ST18,ST8SIA3,SDCBP2,B4GALNT1,NCAM1,ST8SIA5,ST6GAL1,ST8SIA1,ST5,TP53BP2,ST7,ST8SIA2" Drug CID000005376 AC1L1K7T Stitch 1.24E-03 1.00E+00 8.46E-03 9.62E-02 128 632 "SERPINA3,OSBPL6,OSBPL8,ALCAM,BCAR3,KCNT1,CDK10,NCOA1,BARD1,FGF17,CFLAR,BMPR1B,MTMR2,CALM1,RUNX1T1,FOXN3,CHGA,CHGB,CHM,CLCN3,CLCN4,CLU,SULT4A1,CNTFR,SLC4A8,CREM,NCOR1,NCOR2,CRYM,CSF1,CSF1R,CSF2RA,CSF3R,PLCXD3,GREB1,ST18,HDAC9,SPATA2,GSDME,CALN1,DRD1,TSPAN5,EGFR,OLIG2,DMTN,ERBB2,ERBB4,PTK2B,ZMYND10,FGFR1,FGFR3,FLT1,TRIM16,SULT1C4,MSTN,GFRA1,GFRA2,PPARGC1A,KCNMB4,GPER1,TMEM121B,PLCD4,NR3C1,HSD17B1,HTR2A,IGF1,IGFBP1,NKD1,IL6ST,KCNMA1,KIT,LIFR,ADAM11,MYH6,MYO5A,BEX5,NAP1L1,NDUFA5,NFIX,NODAL,NOS1,NOVA1,NTRK2,NTRK3,OGG1,OXTR,PDGFRA,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PPARA,MED1,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,BCAS3,PTK2,RBBP8,ZDHHC4,RXRG,SAFB,IL17RB,CCDC88A,SMARCA4,DDN,SSTR1,SSTR2,PLCB1,TF,LEFTY2,ZFP91,TNFRSF1B,TNR,PIK3R5,RBFOX2,NR2C2,USP1,XRCC4,SCG2,PLD4,NUP214,NETO1" Drug CID000000654 diethyl phosphate Stitch 1.24E-03 1.00E+00 8.50E-03 9.67E-02 32 119 "ACHE,AP2A1,AP2A2,AMPH,ASCL1,BCHE,KYAT1,REPS2,EPS15L1,CLTA,CLTB,CLTC,HAPLN1,SPATA2,SNAP91,DMPK,EN2,DMTN,GHR,AGFG1,ZIC5,MTTP,NEUROD1,RLBP1,SH3GL3,ADHFE1,TCF12,TF,SIRT1,RGMB,IFT88,ST8SIA2" Drug CID000003542 1-(5-isoquinolinesulfonyl)-2-methylpiperazine Stitch 1.29E-03 1.00E+00 8.79E-03 1.00E-01 70 314 "ADCY5,ADCY6,ADCY8,AGT,DGKZ,DGKD,ALDH7A1,CACNA2D1,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,AIFM1,DGKI,LRBA,NOG,CRLF1,CHRM1,MYL6B,DGKB,DGKG,EDN1,EDN3,EDNRA,EGFR,ERBB4,FCGR1A,FCGR3A,ACTL6B,GAP43,MSTN,STON1,NR3C1,HTR2A,MYLK2,IGF1,ITGAM,LAMA2,ASPRV1,MBP,MYBPC1,MYL3,NCF2,NODAL,NPPA,NRGN,PDE3A,PKM,PLEC,TRHDE,PTPA,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,LAMA1,PTHLH,MAPK12,FNDC3A,TMEM132D,VAMP1,TAC1,TAC3,TACR1,LEFTY2,ACTR6,TNS1,PLD4" Drug CID000025437 cerbroside Stitch 1.29E-03 1.00E+00 8.79E-03 1.00E-01 23 77 "ARSE,ASPA,GPC2,CBS,CLTB,QKI,GAL3ST1,GALC,NKX6-2,MAG,MBP,PLP1,PMP2,PRKCB,PRKCG,PKN2,PRKCZ,IFT122,NEU4,TPD52L2,UGT8,SHD,GAL3ST3" Drug ctd:C545373 ponatinib CTD 1.29E-03 1.00E+00 8.79E-03 1.00E-01 21 68 "CSF1R,EGFR,EPHA5,EPHB1,ERBB4,PTK2B,FGFR1,FGFR3,FGR,FLT1,FYN,JAK1,JAK2,KIT,NTRK2,NTRK3,DDR2,PDGFRA,MAPK3,RET,TEK" Drug 5445_DN Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "LTBP4,APBB2,PPFIA3,BRINP2,GYG2,BTRC,CBFA2T2,ARHGEF6,COL4A5,AKAP12,CRY2,CNTNAP2,CTH,RUSC2,TOM1,CNNM1,EFNA3,EZH1,ZNF589,FGFR1,FHL1,SEMA4D,AHDC1,RAB30,GRIK5,HNMT,NTRK2,MAPK7,ATG16L1,EMID1,ASAP3,SHANK2,ZKSCAN3,SLN,COA1,ZSWIM8,SPART,MAPK8IP3,PLCB1,ATP11A,KIAA0930,ARHGEF12,SLC44A1,KCNK12,SPHK2,WNK1,EPM2A,SENP7" Drug 2519_UP Avermectin B1 [71751-41-2]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ARID1A,BCAR3,AZGP1,NRP2,CACNA1I,USP2,CRLF1,CLCN4,NCOR2,RGS6,GSDME,E2F5,USH1C,SRPK3,ELN,EPB41,KIAA1109,FGFR3,PDLIM5,GNAL,KCND3,KIF5C,LAMA2,MEF2C,AFDN,ADAM22,PMP22,PRKAR1B,MAPK7,PLPPR1,PTPRB,ZSCAN2,KLHDC8A,ROM1,RTN1,SCN2B,PPM1E,ASAP3,SLC1A3,SLC11A1,SPTAN1,RAP1GAP2,KIAA1107,PSD3,PCDHA5,TIAM1,TK2,STMN4" Drug 7548_DN DNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AP2A2,MRTFA,APBB2,CDK10,ATP2A2,ATP2B2,ARHGEF2,PLEKHB1,TPP1,SULT4A1,HOMER3,NCOR2,PDE4DIP,SDC3,SPOCK3,ATN1,DTNA,SIDT2,TENM1,EML1,F3,ZNF589,CGREF1,EML4,PTGDR2,ATXN2L,MATN3,NF1,NFYA,NPR2,KCNK10,CDK18,PLXNB1,PPP5C,PID1,RGS3,NEK11,SUPT20H,AMBRA1,SLC6A9,DDN,JMJD6,ARHGEF9,COBL,UGT8,ZNF45,MVB12B,EPM2A" Drug 4552_DN Ergocryptine-alpha [511-09-1]; Down 200; 7uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,ACTN1,NME5,APC,ALDH4A1,LRRFIP1,LHX2,CLCN4,IQCK,CHD1L,HAPLN1,VCAN,KBTBD11,OPTN,MRNIP,PLEKHO1,FGFR1,TRAF3IP2,GLS,GPR37,GRIK2,SHISAL1,DIPK1A,MAPT,MBD1,MX1,NASP,NUMA1,PDPK1,RC3H2,GON4L,RAD51D,FBXW7,SH3BP2,DZIP1,SLC14A1,SLC20A2,ZBTB43,DDN,ST5,MAPK8IP3,ASTN2,WWC1,KIAA0930,ARHGEF12,TIAM1,TNS1,WIPF1" Drug 3406_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "RALGAPA1,KIDINS220,AMPD3,APOC1,PPFIA3,ALDH4A1,SLC2A11,KIF1A,CACNB2,CACNA2D2,TPP1,GREB1,DRD1,RCAN1,EDNRA,EGR3,HSD17B14,SCML2,TMEM164,FHL1,GPR153,TXNL4A,GLS,ATF7,NR3C1,ATXN2L,KCNF1,SHC3,MGAT3,PCBP3,PDE3B,SAMD9,ZSCAN32,FAM120C,ZDHHC14,RGS3,SGK1,SYBU,SNCA,KDM4B,INKA2,STX1A,POPDC3,EXOC7,VGF,REEP1,UBE3B,PHTF2" Drug 6134_DN Ronidazole [7681-76-7]; Down 200; 20uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ALAD,APAF1,NCOA1,N4BP2L1,BACH1,CAMK2G,CDC42,ARHGAP33,RAB33A,ZFYVE9,CLCN4,NMT2,CSF1,ZFYVE16,SMG7,SLC12A6,MRNIP,COQ7,NCALD,ANKFY1,WASF3,POLL,LILRA2,LPAR4,MAP4K5,MAP4,N6AMT1,OMG,PDE4D,CCSER2,PTPA,RAB3A,MAP6D1,SH3BP2,DOCK10,FNDC3A,ANKRD6,TMCC1,ZCCHC24,SS18,KCTD2,PARD3,RBFOX2,TPM1,TRPS1,HIRA,PLPPR2,EMSY" Drug 2883_UP Trolox [53188-07-1]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ALK,ATP1A3,CFAP410,HAP1,SCARB1,ARHGAP33,CRY2,TMCC2,DTNB,DYRK1A,HSD17B14,ERBB2,DLC1,FYN,SYT17,RND1,GPR17,SOX21,HLF,IRF8,KCNMA1,KCNN2,AFDN,ADAM22,NFIX,OGG1,PLTP,CEP41,MAPK7,C1orf54,ZNF493,ZMAT4,TRIM68,RGS12,ZFP2,RASA3,DZIP1,SHANK2,SCMH1,IZUMO4,ARC,TBCEL,TK2,LILRA4,FAM155A,XRCC4,EVI5,KCNAB1" Drug 2284_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "DPF1,LTBP4,BIN1,ANK1,PRX,ARHGDIG,MARK4,SLC2A11,CFLAR,GYG2,CACNA1G,INA,CDH2,SULT4A1,LY86,CNTFR,WHRN,CSF1,CHD5,DMPK,KCNMB2,SPEG,GPR162,C1QL1,GPM6A,GRIK1,KCNJ5,KCNQ3,NNAT,PALM,PCDH9,CEP41,C1orf54,RGS4,RGS10,SEMA6D,SLC1A2,SLC2A5,OGDHL,SNAP25,PEG10,ARHGAP26,TACC1,ADGRL3,WSCD1,SZT2,FLRT2,WIPF1" Drug 4844_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "TRMT9B,ADGRB1,NRP2,CACNB2,ZFYVE9,ARHGEF6,CSF1,CNTNAP2,TBC1D5,BRINP1,MFAP3L,MAGI2,KLHL3,ATN1,ST8SIA3,CDHR1,ABCA8,GAD1,HBS1L,GPM6A,NR3C1,ATXN2L,SYNPO,ICA1,TJAP1,KCNMA1,LSS,MID1,MPP2,FTO,MAPK8,FAM120C,SH3GL3,ASAP3,SMTN,PKNOX2,SP2,STX1A,AJAP1,ARC,PDLIM2,WSCD1,TCF7,ZEB1,DOCK9,TK2,NT5M,ST7" Drug 6476_DN Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABAT,AMPD3,BIN1,ADAM15,BAIAP3,BTRC,CA12,RAB28,ARMCX2,HP1BP3,SMG7,DRD1,ING4,EN2,EPB41L2,FGFR1,SEMA4D,OGA,FYB1,TXNL4A,MSL3,STON1,GPER1,CNTRL,KCNH2,KLC1,IPO5,LMO2,ZNF862,NELL2,NFYA,NPTX1,SIDT1,WDR25,RGS3,RGS10,RNASEL,SLC6A8,SLC15A2,LIMCH1,SOX2,THSD1,MAPK8IP3,SMG6,THRA,TPM1,CDK20,URM1" Drug 5753_DN Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AK2,APBB2,CDC14B,CFLAR,MAP7,CHM,B4GALT6,TPP1,ENTPD4,PDE4DIP,SLITRK5,SDC3,PPP6R2,RUSC2,CDON,DNM2,SORBS3,EZH1,SCML2,ANKFY1,ATP2C1,OGA,TMEM8B,KIF3A,RASSF8,DHX35,IL11RA,GIT1,ADAM22,ZNF862,NUMA1,SLC25A23,ZNF426,MAPK7,GRAMD1C,CNNM2,ATG16L1,FAM184A,CCDC25,TCP11L1,TRAPPC13,LARP4,MAPK8IP3,CEP68,DIP2A,CRTC1,VGF,XRCC4" Drug 3879_DN Homosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "SEMA7A,APP,CDK13,SLC2A11,ALDH7A1,NEURL1,FADS2,ARHGEF4,DAPK3,SPATA2,DSCAM,NCALD,CDKL3,KAT8,ZNF589,GCNT2,HSD17B1,INPP5B,KCNH2,KHK,MAOB,MMP17,ADAM22,NF1,SERPINE2,PLCD1,PLXNB1,TNPO2,POLG,MAPK10,PRODH,PTHLH,FAM120C,RAB3IL1,CCDC40,ANKRD6,SNCA,FCHO1,RGL1,STX1A,POPDC3,ARHGEF12,DAAM2,PLPPR2,VIPR2,KCNK12,SPHK2,GDPD5" Drug 283_DN quercetin dihydrate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ACADM,ASIC1,NDRG2,CDC42BPA,PPFIA3,ARNTL,MTMR9,MYRF,BAIAP3,CH25H,CLDN10,KRIT1,INA,ARHGAP33,KIAA1549L,STOML1,IFFO1,KLHL3,DPH1,OPTN,FGFR1,CGREF1,NCKAP1,GNAO1,PRDM5,IGF1,KCNJ5,CTNNA3,NTRK3,NKAIN1,ENOX1,SAFB,PREX2,PKNOX2,SLC15A2,SNCA,KDM4B,ARHGAP26,TBL1X,TCF7,TEX15,THRA,TMPRSS5,TUB,SLC13A3,WNK1,SLC17A7,KCNAB1" Drug 2132_DN Xylazine [7361-61-7]; Down 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "GRAMD1B,MARK4,SYNJ2,SCARB1,ENTPD6,CHM,TAOK2,VCAN,ARHGAP32,SGSM2,SIDT2,EFNA3,SUGP2,ING4,PCOLCE2,PDLIM5,TRAF3IP2,ADAM28,KCNJ5,OGDH,P2RY1,PDPK1,PLCB2,RETREG2,MINDY2,PRKAB2,RALGDS,BSDC1,PAQR6,RXRA,ZNF821,KDM4B,SPATA7,RBM26,SYT11,VAMP1,ATP11A,DNMBP,TBL1X,TCF4,SZT2,R3HDM1,PARD3,TNNT1,TNS1,ZNF142,REEP1,KAT6A" Drug 7384_UP Mephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "LTBP4,APBB2,APC,PPFIA3,AQP4,ADGRB2,BAIAP3,HAP1,TAOK2,NRG2,NCOR2,USP6NL,DBT,CNIH3,RUSC2,EXOG,DPH1,EDIL3,EFNA3,IRAK4,PLEKHO1,COQ7,ETV1,ZMYND10,FGF1,FGFR1,DENND2A,GRM2,MAPT,TAGLN3,PLCD1,PRODH,CNNM2,PTCH1,PTPRN2,FAM120C,TMEM231,RGS4,MYH14,KIRREL1,TRAPPC13,MAPK12,CSRNP3,ST6GAL1,BTBD7,SLC20A2,ZKSCAN3,TRIO" Drug 1544_UP Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADORA2A,BIN1,MARK4,ATP6V0A1,HAP1,HOMER3,CSF1,VCAN,DNAJC6,EFNB3,EIF4G2,CEND1,FOXG1,AGAP2,TDRKH,GRM1,GRM2,GSN,ICA1,ITPKB,KIFC3,LMO2,AFDN,PLCD1,PRKAR1B,PTN,SEC61A2,DOCK10,ZNF365,PKNOX2,SLC6A8,CXXC4,HECW1,ERC1,PEG10,CDK19,ZBTB43,INKA2,STX1A,KIAA1107,TCF4,PSD3,TK2,PLPPR2,WIPF1,ZBTB14,EPM2A,RNF170" Drug 6478_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADORA1,CDC42BPA,CCDC181,SLC4A4,SCAPER,BSN,CFAP410,KALRN,CDH8,ZFYVE9,WHRN,LRIG1,ARHGEF10,PDE4DIP,EDN3,EGR3,DENND2A,GALC,INPP5K,SRCAP,GNAS,LPAR4,KCND3,KCNMA1,SMAD1,MAN2A2,OPRL1,SLC25A23,LRP12,PPP2R2B,MAPK8,ASAP3,ST6GAL1,FAM214B,SLCO1A2,SNAP25,FAIM2,PDZD2,ZCCHC24,HECW1,SS18,TRIM2,TNS1,TRO,VSNL1,SLC30A3,WNK1,EPM2A" Drug 2273_DN Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABHD6,SLC12A5,APBB2,DNAH17,ATM,MTMR3,FOXN3,CNTN1,ENTPD4,SH2B1,RASSF2,ATN1,EFNA3,EGFR,LRRC23,FGFR1,FOXG1,AGAP2,DISC1,GLYR1,INPP5B,LSS,MPP2,ADAM22,ZNF862,NUMA1,RETREG1,MAPK10,PTN,RAB3A,RGS10,KLHDC8A,TRA2B,SNCA,WDTC1,EMC1,PLCB1,DOCK9,AP4E1,TK2,KAT6B,CABIN1,TRPC1,VGF,KCNAB1,NUP214,SENP7,JPH3" Drug 3625_UP Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASIC1,AMPD3,GAS7,ASCL1,ZSCAN18,ATP1A2,SLC2A11,CADM3,CFAP410,CACNA1D,INA,CBFA2T2,SULT4A1,NRG2,AATK,MICAL2,CTIF,DCT,RABGAP1L,TMCC2,SGK2,SPEG,CAMSAP1,FHL1,AFF2,RND1,TPPP,GRIK1,GRM2,MGAT3,CD200,NF1,NPY,PACSIN1,RNASE1,EMID1,SELL,RASA3,PDZD2,SOX10,EMC1,HECW1,ACSBG1,WSCD1,CRTC1,UBE3A,CA10,DNALI1" Drug 4255_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASIC1,ALAD,APOC1,ADAM23,ADGRB2,KSR1,BAIAP3,SYNGR3,CDH10,CRLF1,TPP1,CDC42BPB,HINFP,EDRF1,DTNA,TOM1,DYRK1A,SIDT2,PLXNC1,SORBS3,DMTN,KIAA1109,FGF1,C1orf61,AFF2,CSPG5,SEPT9,RUNDC3A,GPR75,CNTRL,ITPKA,KCND3,MGAT3,ADAM22,NDP,TNPO2,RAB3A,ENOX1,ZNF821,KANSL3,SLC6A9,MYH15,KDM4B,DDN,MAPK8IP3,THRA,TIAM1,VGF" Drug 4799_DN Zalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADCY6,AP2A2,PLA2G6,C1QTNF3,LTBP4,AMPD2,BIN1,CFLAR,MTMR3,CFAP410,LHX2,MICAL2,PDE4DIP,SDC3,ARHGEF4,NOS1AP,TM9SF4,EFNB3,ANKMY1,ECSIT,CAMSAP1,MSL3,GNG3,ELOVL5,HNMT,MAPT,MBD1,NF1,NOS1,NUCB1,MBOAT7,RAB3A,RNF220,SBF1,SH3BP2,ABLIM3,SMTN,FAM214B,SOX2,MCF2L,SZT2,ARHGEF12,TMEM121,KAT6B,CABIN1,ZKSCAN5,XRCC4,SSPN" Drug 4553_UP U-62066 [87151-85-7]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ACHE,AMT,EPB41L5,GAS7,CDK13,CCDC181,SLC4A4,NRP2,EPS15L1,CNTNAP2,MFAP3L,RABGAP1L,DRP2,EDN1,HIPK3,DLC1,AFF2,TBR1,FYB1,ZNF44,SIGLEC8,ALDH1L1,SRCAP,ADAM28,GNG3,GPM6B,GPR19,ICA1,IL6ST,KCND3,LIG4,MMP16,NCAM1,ODF2,FA2H,POLG,POU6F1,PROX1,CCDC40,SH3BP2,DZIP1,ZNF415,SOX2,IZUMO4,BEX1,SS18,KIAA1107,PCDHGA10" Drug 2027_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "APOC1,ARNTL,BCL7A,RUNX1T1,FAM189A2,CPS1,C2CD2,CRYM,OSBPL3,HDAC9,RCAN1,TOM1,EDNRB,EFNB3,EFS,F8,SUCO,DPYSL4,POMT1,ATP2C1,GLS,GNG3,PADI2,NXPH3,ICA1,SCAMP5,MYT1,NELL2,NTRK3,PFKFB3,LRP12,PPP2R5C,MAPK10,PRPH,CRTAC1,TCP11L1,AP1AR,SH3BP2,SLC15A2,ELMO2,DOK5,SPTB,ZC4H2,SYN2,PHF24,PARD3,LAT2,XRCC4" Drug 6743_DN Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASIC1,CDK10,ARHGDIG,LDLRAD4,LHX2,NMT2,RAB26,WHRN,CRMP1,MICAL2,BRINP1,MFAP3L,ATN1,AASS,EN2,LRRC23,MTSS1L,ST3GAL6,ZNF589,GAB1,SIGLEC8,AHDC1,POLL,TDRKH,GRK4,ICA1,INPP5B,MBD1,ZNF862,NEUROD1,NF1,NOS1,ODF2,KCTD15,PRKAR1B,RALGDS,RPS6KA2,FOXRED2,SCG5,FUZ,DZIP1,TSNAXIP1,BEX1,RPGRIP1L,PCDHA5,MAP3K12,PRDM2,KCNAB1" Drug 6806_DN Cyproterone acetate [427-51-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABHD6,CDC42BPA,CDC14B,ARRB1,ARRB2,PLA2G4C,RIPK1,SYNJ2,BTRC,LHX2,RCHY1,FEZ1,MFAP3L,PARD6A,DLG3,EZH1,ZNF589,FECH,FHL1,INPP5K,GPD2,CNTRL,MAP4K5,PCDH9,SERPINE2,PPP5C,PRKAR1B,TMEM104,RPS6KA2,ZFP30,FERMT1,CHD9,RAB3GAP1,ZKSCAN3,UHRF1BP1L,UNC5B,TROVE2,NXT2,FCHO1,SYT1,ASTN2,TCF7,TMEM121,CHST8,SF1,ZNF24,MFF,EPM2A" Drug 6982_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ALCAM,AMH,BCAS1,RGS20,ASPH,CFLAR,PROM1,CRLF1,CNOT8,TPP1,VAX2,FEZ1,ARHGEF10,CTH,ENO2,KAT8,DPYSL4,GAP43,ERAP1,INPP5K,AHDC1,GFER,ICA1,TJAP1,VWA5A,MAP4,MIA2,MPP2,ZNF862,PALM,PDE4A,TMEM104,ZSCAN32,ZSCAN2,RGS12,SBF1,PKNOX2,ZKSCAN3,COA1,EMC1,NXT2,ASTN2,TK2,TPM1,CHST5,ZMYND8,REEP1,SSPN" Drug 6685_DN Meglumine [6284-40-8]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "KCNAB2,PDXK,MARCH3,ATM,CFLAR,SYNJ2,KRIT1,SOCS6,RAB26,ENTPD4,SLITRK5,RUSC2,SMG7,SGSM2,NBEA,ATP2C1,CGREF1,TXNL4A,COPS8,POLL,PCLO,IL6ST,TM6SF1,MSRA,OPCML,PAK3,PLCD1,LRP12,PTCH1,PTN,PTPRN2,TMEM231,MRPS18A,SEC61A2,KIRREL1,PPP1R9A,AMBRA1,FBXO11,ST6GAL1,TNIK,CAND2,KIAA1107,ARHGEF12,HIRA,WIPF1,HPS4,NAV3,KCNAB1" Drug 1295_DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ANK2,PPFIA4,ARRB2,CDK13,NCOA1,NUMB,C5,CANX,SPAG9,TPP1,CHD1L,RUBCN,ABI2,FECH,CINP,DISC1,GART,GLYR1,GLS,HTATSF1,HSF2,ICA1,NUCB1,OGG1,OLR1,POLG,MINDY2,RAD51D,RAD52,GTDC1,SH3BP2,DZIP1,SLC15A2,ZCCHC24,SPTAN1,NXT2,MLC1,ARHGEF9,ATP11A,EXOC7,TBL1X,TNNT1,TNS1,TPD52,XRCC4,ZNF24,REEP1,WIPF2" Drug 7496_UP Suramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,AP2A2,DOC2A,APLP1,PPFIA3,CDK13,MARCH3,NCOA1,ADGRB2,CFLAR,CAMK2G,SRSF11,VAX2,CDON,EFNB3,CELSR3,EIF5,C3orf18,NCALD,CDKL3,ANKMY1,AGAP2,COPS8,POLL,TJAP1,VWA5A,NEK1,CNOT4,PDE3B,NLE1,PPP5C,CNNM2,PEX5,CARF,EMID1,SYBU,RPH3A,SLC6A8,ST5,MAPK8IP3,TACC1,PARD3,TRIO,PLPPR2,MAP3K12,HPS4,PCBP4,UBE3B" Drug 5014_DN Bemegride [64-65-3]; Down 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ARID1A,ALCAM,MRTFA,AMT,APP,PLA2G4C,SLC4A4,CFLAR,ARHGEF7,CACNA1D,CLGN,RIMS2,GPRASP1,DAPK3,MFAP3L,DNM1,DPH1,DSCAM,EFNA3,SUGP2,SORBS3,ING4,FER,FGFR1,SRCAP,GLS,CACFD1,TJAP1,IL6ST,KCNN2,MSI1,ZNF862,PLCD1,PPP2R2B,FAM120C,RAB3A,RALGDS,SEC61A2,SBF1,CPEB3,FAM214B,LIMCH1,TSPYL2,PHLDB1,EXOC7,PCDHA6,ZNF34,XRCC4" Drug 4823_UP Fosfosal [6064-83-1]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ACTN2,KIDINS220,APC,LDLRAD4,BTRC,SRSF11,TPP1,STOML1,DNAJB5,ENTPD4,PDE4DIP,CNTNAP2,DZIP3,TBC1D5,GIT2,MFAP3L,EFNA3,ING4,RRAGB,KIAA1109,HBS1L,RND1,ATXN2L,IL6R,JAK2,LIG4,LSS,MAN2A2,MDM4,MSR1,NEK1,NPR2,PALM,ZNF493,NEK11,UEVLD,KDM4B,IQSEC2,SAMSN1,AJAP1,SMG6,PCDHA5,CABIN1,XRCC4,ZIC3,SH3GLB2,SLC30A3,JMJD1C" Drug 165_UP exemestane; Up 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "KCNAB2,APBB2,PRX,N4BP2L1,MPDZ,ST3GAL5,RAB29,KALRN,FOXN3,SLIT2,CNTFR,CNTN1,CRMP1,ACOT8,SUGP2,MBNL2,ETV1,EFEMP1,FGFR1,C1orf61,AFF2,PDLIM5,SRCAP,CRCP,SPACA9,GRIN1,PRDM5,NXPH3,NOS1,NPPA,SLC11A2,NRGN,NUMA1,PALM,PTPRD,RLBP1,TMEM206,SEMA6D,ASIC4,SLC12A2,SNAP25,TMCC1,SON,ATP10B,GANAB,NSFL1C,TP53BP2,CA14" Drug 6433_DN 5707885; Down 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "PKP4,CNTNAP1,GAS7,ARNTL,BCL7A,GYG2,CFAP410,SEPT7,TAOK2,FAM189A2,VAX2,AKAP7,BAG4,SMG7,KBTBD11,EXOG,DMPK,DNAH9,ATN1,PLEKHO1,STX2,FHL1,TRAF3IP2,ZMYND11,ERAP1,HTATSF1,FERMT2,GRIK5,RASSF8,ITPKB,KHK,MAP4,MAPT,NF1,PIK3R1,ELOVL2,RAB3IL1,RGS3,ITSN1,FNDC3A,SLN,KDM4B,TCF7L2,R3HDM1,PLPPR2,LAT2,HPS4,UBE3B" Drug 6777_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADCY6,AMT,SEMA4G,CACNA1I,CA4,SLC16A4,FADS2,VAX2,CSF1,GREB1,CTIF,ZNF804A,ING4,MRNIP,GLYR1,PCLO,SPACA9,NR3C1,KITLG,MSI1,NOVA2,NPTX1,NUMA1,OPRL1,CDK18,LRP12,PTAFR,PTN,PTPRO,SLC6A15,RGS12,MYH14,KCNIP1,SNCA,KDM4B,TROVE2,PLCB1,ATP11A,TBCEL,RPGRIP1L,SZT2,PSD3,ARHGEF12,GPR161,TPM2,CHST5,FAM155A,CLIP2" Drug 6421_DN PF-00539758-00 [351321-34-1]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "RALGAPA1,ADORA2A,AP2A2,LTBP4,BIN1,APC,MARK4,ATP2A2,SCAPER,GYG2,ARHGEF1,CBFA2T2,RAB28,TPP1,SULT4A1,CREB5,VCAN,CNTNAP2,SDC3,SPOCK2,STX2,PDLIM5,CGREF1,INPP5K,ZNF276,KCNB1,KIF2A,NELL2,SLC11A2,MAPK7,GAL3ST4,RGS10,RGS12,ZNF671,SLC12A4,SNCA,KDM4B,SPTB,NPAS3,DDN,LHPP,TBCEL,BHLHB9,R3HDM1,TNS1,OSBP2,LMF1,NUP214" Drug 3307_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AP2A2,ALCAM,LTBP4,APBB2,GAS7,APOC1,ARRB1,MARK4,NCOA1,SYNJ2,ARHGEF2,PLEKHB1,ZFYVE9,PDE4DIP,CTH,DTNA,FEM1B,VPS13B,FHL1,C1orf61,CGREF1,ERAP1,GLYR1,GPER1,HNMT,SCAMP5,NEK1,NF1,NPTX1,PPP2R5C,GON4L,RGS10,RNASEL,FBXW7,PEX26,ZCCHC24,SPART,LHPP,PHLDB1,EXOC7,TCF7L2,TRIM2,TMPO,CABIN1,VGF,XRCC4,ZBTB14,ZIC3" Drug 5481_UP Imidurea [39236-46-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "CDK13,MARK4,ATP1A3,CACNB2,CALB1,FOXN3,FADS2,CSF1R,DBT,HP1BP3,DTNB,EPB41L2,DMTN,RASGRP2,MTSS1L,ERAP1,GNG3,DHX35,ICA1,KCNJ10,MOBP,ADAM22,MSR1,TAGLN3,NELL2,P2RY1,SNTG1,RETREG1,PACSIN1,PPARA,ACSM5,RAB3IL1,KCNIP1,FUZ,RPH3A,SLC15A2,ELMO2,PDZD2,KIF21B,KDM4C,PEG10,SEMA4A,ZMYND8,FLRT2,VAV2,ZNF45,SPHK2,SEMA3B" Drug 3786_UP Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ACTN2,AP2A2,GAS7,SLC4A4,N4BP2L1,C5,CALB2,ADGRG1,SLC22A6,NMT2,SULT4A1,CREB5,DCT,ECM2,PLXNC1,ING4,SEMA4D,PDLIM5,GAP43,RUNDC3A,GRM2,IGF1,KCNC1,KCND3,LMO1,MMP16,MOBP,SLCO1C1,NUMA1,OPCML,OPRL1,PDGFRA,TNPO2,PTAFR,PTN,ZMAT4,KIRREL1,EMID1,FRMPD1,DOCK10,SCN3B,MAPK8IP3,SYT11,HIF3A,NDRG4,EVI5,KCNAB1,PAK5" Drug 5099_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ARID1A,ADD2,CDC14B,SEMA4G,SLC4A4,KIF1A,CFLAR,ARHGEF7,FUBP1,MYRF,LARGE1,TAOK2,NMT2,ARMC8,CREM,CSNK1E,PDE4DIP,DCAF4,DAPK3,FAM13A,SORBS3,HSD17B14,ETV1,FGFR1,BAIAP2,SEMA4D,GAB1,B4GALNT1,GLI2,IL12A,LSS,NUMA1,ODF2,KCTD15,CDIP1,FAM184A,RGS4,GSTCD,ROM1,FBXW7,ZFP30,SLN,ZNF415,RBM34,WDTC1,PHLDB1,SYN2,TRPC1" Drug 7284_UP Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "MRTFA,APC,CDK10,ALDH7A1,KIF1A,BCL2L2,CFLAR,CLTB,HOMER3,PDE4DIP,SLITRK5,TOX,KIAA0513,RUSC2,EDNRA,BAIAP2,AGAP2,EFCAB2,ZNF44,GAD1,GPR17,DIPK1A,INPP5B,KPNA5,LIG4,MAPT,SCAMP5,PALM,PDE4B,MAPK7,PTCH1,NCBP3,SCN8A,SEC14L1,ZNF821,SCG5,SH3BP2,DOCK10,AMBRA1,SLC1A7,ARHGEF40,THSD1,VAMP1,KAZN,RUNDC3B,WIPF1,WNT7A,EPM2A" Drug 6221_DN Calycanthine [595-05-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "SYNJ2,KYAT1,NIPBL,CTH,PPP6R2,GIT2,SGSM2,FGFR1,FHL1,AHDC1,GPR19,LIG4,MAP4,MAPT,MIA2,MITF,GIT1,NCAM2,NFYA,NPR2,NUCB1,OGG1,PC,PCDH9,PDE4A,SMIM7,FA2H,CNNM2,LRRC49,RIPOR1,RAB3IL1,RGS10,RPS6KA2,SUPT20H,ZKSCAN3,NCDN,ELOVL4,ANKRD12,TBL1X,TCF7,NSD1,TIAM1,PARD3,RBFOX2,RPRM,VAV1,ZNF23,MVB12B" Drug 3784_UP Vincamine [1617-90-9]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "TTYH1,ADGRF5,TRMT9B,LGR5,ATP1A2,MTMR3,CACNA1G,SEPT7,JAM2,KIAA1549L,SULT4A1,AKAP7,SNCAIP,CYBB,DNAH9,EFNA3,ING4,MRNIP,LRRC23,EPHB1,SCML2,FYB1,GAB1,RAB30,GNAL,GNG4,GPR17,GRM7,ADAMTS6,IGFBP1,NUMA1,PBX1,CDK18,PDE2A,ENPP2,RASGRF1,GAL3ST4,PNMA8A,EMID1,RASA3,CPEB3,KDM4C,ACSBG1,COBL,PCDHGA1,SLC44A1,HEY2,ZIC3" Drug 7445_UP Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "SLC12A5,ADORA1,ADORA2A,NME5,AK2,PPFIA3,SLC4A4,SCAPER,MAGI1,SOCS6,RAB33A,PICK1,CREM,PDE4DIP,PPP6R2,MFAP3L,SPOCK3,OPTN,ERCC2,C1orf61,IQCG,ERAP1,USP19,RASSF8,NF1,CNOT4,SERPINE2,SMIM7,MINDY2,RAB3IL1,KCTD17,GSTCD,ROM1,PAQR6,BCAN,SLC1A7,FAM214B,ZCCHC24,ZHX3,EMC1,ZBTB43,FAM168A,KIAA0930,TCF7L2,SZT2,AHCYL2,TNS1,KAT6A" Drug 122_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "BRAP,GRAMD1B,ADORA2A,PDXK,ARNTL,ASCL1,ALDH4A1,CFLAR,CACNA1I,P2RX6,DNAJB5,AKAP7,IQCK,PPP6R2,C2CD2L,DNM2,DTNA,ELAVL4,ZNF589,FGFR3,AFF2,INPP5K,RUNDC3A,GOLGB1,KCNJ5,KHK,VWA5A,MAP4,MIA2,NEK1,MBOAT7,TMEM104,PTN,ZSCAN32,ZFHX4,FOXRED2,FERMT1,ABLIM3,RAB3GAP1,ZC3H13,CEP68,KAZN,EXOC7,TRIM2,TK2,SEZ6L,TSN,SEMA3B" Drug 2931_UP Tocainide hydrochloride; Up 200; 17.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "BIN1,CDC42BPA,ANK2,ANK3,APBB2,PDE8B,MYRF,TAOK2,HOMER3,CRY2,PHF14,CTNND1,DCAF4,TNK2,RASGRP2,STX2,TBC1D16,KAT8,GAD2,GATM,RUNDC3A,GRM7,ICA1,SCIN,KCND1,MYO6,ZNF862,NPTX2,PLEC,SLC25A23,PPARA,PTAFR,RGS10,SEC61A2,FOXRED2,FAM102A,ANKRD6,SMTN,PEG10,SPTAN1,TROVE2,FCHO1,SZT2,SLC19A3,TK2,TNS1,TPM3,VGF" Drug 1747_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABR,CNTNAP1,CDK10,ARNTL,MTMR9,CADM3,SCAPER,MTMR2,HIP1R,AKAP7,SEC31B,SPOCK2,DCTN1,DPH1,EFNB3,ING4,EPB41L2,ECSIT,TUBB4A,ZNF589,TRMO,PRRC2B,LILRA2,PTPRT,KCNN1,KHK,GIT1,NUCB1,PLCB2,POLR2F,PRPH,RAD52,SAFB,ATXN2,SH3GL3,AMBRA1,NSFL1C,VPS13A,OBSL1,TMPO,KAT6B,ZMYND8,UBE3A,NPDC1,ZNF24,WNK1,GDPD5,ZNF248" Drug 451_DN TTNPB; Down 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "CDC42BPA,SEMA7A,DGKD,SLC4A4,ATP2B2,ATP6V0A1,BAIAP3,HAP1,SCARB1,CHGB,CHRM4,CSF1,RIMS2,GIT2,DCC,RHOBTB1,FEM1B,CELSR3,SUGP2,MBNL2,RGS17,KAT8,SARAF,OGA,GJB1,PRRC2B,BTN2A1,FAM107A,MAN1B1,ICA1,LAMA2,MEF2C,MT1M,MYO7A,NPY,PENK,MBOAT7,NUDT11,ATXN2,ARHGEF40,SMARCD3,MAPKBP1,SRPK2,SYN1,SEZ6L,FLRT1,NDRG4,AAAS" Drug 3463_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "EPB41L5,ATM,CFLAR,ST3GAL5,C5,BTRC,CACNA1D,RAB28,DCAF8,HDAC4,LYPD1,SMG7,FEM1B,OPTN,MBNL2,ECSIT,BAIAP2,GPD2,HNMT,MAP4,GIT1,ADAM22,LYRM9,NAP1L1,PC,MAPK3,ZSCAN32,PEX5,RNASEL,ROBO1,FOXRED2,SFPQ,FNDC3A,BTBD3,EPN2,RBM34,EMC1,ZBTB43,TSPYL2,CAMTA2,SYT1,SEMA4A,TMPO,RPRM,PLPPR2,VAV2,LMF1,XRCC4" Drug 1811_UP Diprophylline [479-18-5]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "KIDINS220,MRTFA,PDXK,PDE8B,MPDZ,CA12,SYNGR3,FOXN3,ASIC3,RAB33A,RAB28,ZFYVE9,KIAA1549L,PICK1,AKAP7,CSF1R,RABGAP1L,SIDT2,ZNF589,B4GALNT1,SYT17,SEPT9,GPR19,BTN2A1,GUCY1B1,IPO5,MBD1,MIA2,SCAMP5,PALM,SAMD9,PTPRH,PTPRN2,RAP1GAP,RGS10,SFPQ,RPH3A,PEX26,SPTAN1,JMJD6,ROBO3,AHCYL2,CHST8,XRCC4,ZNF32,PCBP4,MVB12B,NUP214" Drug 2214_DN Diazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "KIDINS220,SEMA6A,SRPX,LTBP4,MRTFA,ARHGDIG,PLA2G4C,MARK4,ATM,CFLAR,MTMR3,CACNA1A,HAP1,ZFYVE9,PICK1,AKAP7,CSF1,SDC3,CTIF,SMG7,CDON,DMTN,FGFR1,FHL1,FAM49B,GPR153,HBS1L,SRCAP,RAB30,GNG4,ITPKB,SCAMP5,MPP2,NOS1,MBOAT7,PPP2R2B,TMEM104,RAB3A,RGS12,TCP11L1,ZBTB43,WSCD1,TCF7,RBFOX2,TRIO,ZIC3,KAT6A,RNF170" Drug 4211_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,AGT,TRMT9B,APOC1,ARHGDIG,KALRN,ARHGAP22,LHX2,LY86,PICK1,IQCK,CSF1,RGS6,DZIP3,RIMS2,SEC14L5,RABGAP1L,DTNA,DUSP9,PLXNC1,EPB41,MTSS1L,F5,ST3GAL6,FGFR1,GRM8,GUCY1A2,PACRG,NEUROD1,NF1,NTRK3,PDE4D,PIK3R1,ST8SIA5,PLXNB1,PTPRB,ZCWPW1,MRAS,KANSL3,ASTN2,GPR161,TIMP4,UGT8,VGF,XRCC4,NDRG4,SPHK2,KCNAB1" Drug 3304_DN Calciferol [50-14-6]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABR,ADORA2A,APOC1,BTRC,CAMK2G,ARHGEF2,SOCS6,TAOK2,VAX2,CTH,TBC1D5,MAML1,GIT2,MFAP3L,RCAN1,EFCAB2,FAM49B,RAB30,FERMT2,TDRKH,LIG4,SCAMP5,MPP2,NF1,NFYA,NRGN,PRKAR1B,GON4L,RGS10,RPS6KA2,WLS,ANKRD6,ZNF365,FAM214B,SLC20A2,KDM4B,ZCCHC24,VAMP1,EXOC7,FBXW11,WDR7,KAT6B,ZMYND8,PLPPR2,ZNF45,REEP1,GDPD5,SSPN" Drug 3074_DN Tyloxapol [25301-02-4]; Down 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AP2A2,ATP6V0A1,LDLRAD4,SLC16A4,SOCS6,EPS15L1,BAG4,VCAN,EDRF1,SPATA2,DNM2,DTNA,FAM13A,PLXNC1,EIF1,RASGRP2,ERCC2,PRKAG2,ZMYND11,ERAP1,GLYR1,GLS,GPD2,LILRA2,SLC11A2,ZNF426,PTAFR,PTN,PEX5,RAB3IL1,ZNF493,RXRA,SLC2A5,SLC6A8,ZCCHC24,CDK19,RBM26,ADGRL3,TBL1X,DMXL2,TCF7L2,TPM2,TRPS1,HIRA,XRCC4,ZBTB14,SPHK2,NT5M" Drug 7191_DN Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,ALAD,DGKD,SYNJ2,PTBP2,SOCS6,TAOK2,ARHGEF10,C2CD2L,DLG3,PHF20L1,SUGP2,STX2,EFEMP1,CSPG5,SEPT9,GART,GPR19,GPR37,MATK,MITF,MYO9A,NEK1,NF1,NFYA,CNOT4,NUCB1,SMIM7,APTX,ARID4A,SFPQ,ITSN1,AMBRA1,KDM4B,SON,WDTC1,ZBTB43,SEPT8,FAM168A,DNMBP,TCF7,TCF7L2,TNS2,PARD3,SSBP2,UBTF,UPF3A,MAP3K12" Drug 6342_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "APBB2,ZBTB10,SLC25A14,CNOT8,NMT2,HAPLN1,USP6NL,DCAF8,TOX,SPATA2,FEM1B,ABI2,LPAR6,ACSL4,FCGRT,PRKAG2,FHL1,FAM49B,MPP6,NCKAP1,GBX2,TXNL4A,FERMT2,KIF5C,IPO5,NEK1,LRP12,SYTL2,PTX3,TMEM231,PID1,SH3TC2,DOCK10,AMBRA1,KDM4D,RAB3GAP1,TNIK,SRPK2,SS18,FAM168A,TCF4,TCF7L2,PSD3,SLC35G2,VPS35L,NAV3,SNX27,MPPE1" Drug 3515_UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "APBB2,FAM131A,ATM,CFLAR,CACNA1I,CAMK2A,ARHGEF1,TAOK2,ZFYVE9,ENTPD4,RIMS2,ATP8A1,ERAP1,ALDH1L1,MALT1,LYVE1,GRK4,GRM1,AP4S1,ELOVL5,TJAP1,IL11RA,ADAM22,MX1,ZNF862,PCDH9,PENK,MAPK7,MAPK10,RIPOR1,ZMAT4,SELL,ITSN1,CXXC4,SMARCD3,ZC3H13,PHLDB1,KIAA0930,PSD3,TEX15,TMOD1,PIK3R5,OSBP2,VIPR2,MVB12B,PARP11,EPM2A,NUP214" Drug 641_DN benserazide hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "APC,APOC1,ARHGDIG,MTMR2,CACNA1I,KALRN,SPAG9,NEURL1,ARHGAP33,CHN2,SLC24A2,LY86,IFFO1,SEC14L5,ECE2,HS3ST2,FEM1B,OPTN,EGFR,RGS17,SRPK3,EFS,TRMO,GAP43,ZNF276,GNAS,ADAMTS13,PRDM5,BTN2A1,ATXN2L,MBP,MMP16,NPR2,PLCD1,PTH1R,PTPRN,SUSD4,FUZ,SHANK2,KBTBD4,SPART,SLC19A3,UCHL1,VIPR2,WIPF1,ZBTB16,PMEPA1,STMN4" Drug 1920_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "RBM10,AP2A2,PLA2G6,SLC4A4,CADM3,MPDZ,CDH2,CHRNB2,PICK1,GIT2,C2CD2L,DTNA,LPAR6,CEND1,KIAA1109,OLFM1,FGFR1,GLS,GRB10,GSTM5,SLC2A6,NXPH3,KLF12,KIF2A,MYL3,MYO6,MYO9A,PC,MAPK3,PRPH,CNNM2,PTPRN2,RIPOR1,TMEM206,IL17RB,SUPT20H,ITSN1,ST6GAL1,ZNF430,SMARCA4,SS18,MCF2L,KIAA0930,ZMAT3,SEZ6L,TRPC1,LAT2,REEP1" Drug 6342_UP Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ARID1A,NDRG2,APAF1,ARRB2,ALDH4A1,CACNA1I,IL33,CACNA1D,KALRN,MAP7,CHRNB2,PICK1,CABP1,COL9A2,SH2B1,CSNK1E,MFAP3L,SIDT2,EFNA3,FAM13A,SORBS3,NCALD,ZNF589,FOXG1,GAD2,GATM,GNAL,SCIN,MEF2C,NDP,NUMA1,ODF2,SNTG1,PALM,PENK,CDIP1,PPARA,MAPK8,MASP1,SLC4A3,PKNOX2,SHANK2,IFT122,UNC5B,ACSBG1,VAMP1,CRTC1,THRA" Drug 6674_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ALK,CDC42BPA,APAF1,APC,GAS7,BRINP2,ADAM23,CFLAR,ST3GAL5,LHX2,KIAA1549L,RAB26,CREM,PDE4DIP,SPOCK3,SGK2,TENM1,ANKFY1,LPAR4,GPER1,GRIK2,SPACA9,HLF,DIPK1A,LIFR,VWA5A,MEF2C,NDUFA5,CNNM2,SNRK,CNTLN,PTPRE,RGS10,MYH14,GSTCD,ZFP30,ASAP3,DZIP1,PEX26,FAM214B,SHANK2,TMCC1,LHPP,IQCE,KIAA0930,VGF,TFIP11,PHTF2" Drug 3129_UP Isradipine [75695-93-1]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AGT,CDC42BPA,ARHGAP5,DNAH17,MARK4,MYOM1,KSR1,BMP7,GYG2,MYRF,CACNG1,SEPT7,CHGB,CHN2,DZIP3,RIMS3,DCT,SIDT2,SORBS3,EYA1,C1orf61,KHDRBS3,FYB1,WASF3,ADAM28,GPM6B,GRM1,ITPKA,KCNJ5,MAP4,MBP,MOBP,MT1M,LYRM9,PDE2A,CAMKV,FAM120C,NTNG1,PREX2,BTBD7,IZUMO4,SPTB,STX1A,PLCB1,TRH,VIPR2,SLC13A3,ZIC3" Drug 5748_DN Butacaine [149-16-6]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AP1B1,MTUS1,ALK,SEMA4G,MYRF,SOCS6,DNAJB5,HAPLN1,CSF1,VCAN,EDRF1,GPRASP1,KLHL3,EZH1,CGREF1,OGA,FYN,TRAF3IP2,B4GALNT1,GART,GNG3,GPM6B,TDRKH,DHX35,KCNH2,KIF5C,TM6SF1,ZNF862,FSD1,PPP2R5C,GRAMD1C,PTN,RAB3IL1,ARID4A,SUGCT,CCDC25,RPS6KA2,SH3BGR,SH3BP2,SNCA,DDN,CAMTA2,MAPK8IP3,ELOVL4,CHST8,CABIN1,ZMYND8,CADM1" Drug 4284_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADORA3,ADRA1D,ALK,SYT13,APBB1,KCNAB2,GAS7,N4BP2L1,BACH1,BMP7,BTK,CAMK2A,CD38,NRXN1,DNAJB5,CSF1,VCAN,EDRF1,BRINP1,DBT,FABP7,TBR1,FYB1,HTATSF1,GRIK5,ICA1,LSS,MDM4,KITLG,AFDN,ADAM22,NPTX2,PCSK1,MTRF1L,PTAFR,TMEM255A,MYH14,EMID1,SH3BP2,FRMPD1,RBM34,NFASC,MCF2L,CUX2,VAV1,ADAMTS9,EPM2A,CAMK1G" Drug 4523_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "RALGAPA1,ADCY6,AP2A2,ALDH4A1,CDH10,FADS2,DNAJB5,QKI,WHRN,ABCG1,PDE4DIP,CNTNAP2,TBC1D5,RUSC2,PLXNC1,TENM1,MRNIP,ETV1,DLL3,TRAF3IP2,SYT17,USP19,GPR17,STON1,GRM1,MX1,NASP,NEK1,NF1,CNOT4,STRN3,MAPK3,MAPK7,PID1,FBXW7,SUPT20H,EPN2,SIRT2,ELMO2,IQSEC2,ZBTB43,CRTC1,TMEM121,TIAM1,LAT2,NSD2,WNT7A,XRCC4" Drug 5496_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,ACTN2,C1QTNF3,MRTFA,PKP4,PPFIA3,CDK10,CFLAR,SCAPER,LRRFIP1,MAGI1,CNOT8,NMT2,CREM,NCOR1,PPP6R2,KIAA0513,MFAP3L,RABGAP1L,DSCAM,DCTN4,EPB41L1,STX2,ANKMY1,DLC1,NOP56,OGA,ERAP1,INPP5K,KHK,MPP2,MYO6,PSMD13,FOXRED2,ZNF821,SHMT2,FBXO11,URGCP,SMARCA4,RBM34,STX1A,ATP11A,ANKRD12,ZNF34,PLPPR2,ZNF23,MPPE1,TIGD6" Drug 2986_DN Theophylline monohydrate [5967-84-0]; Down 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABAT,NDRG2,BACH1,CFLAR,KSR1,SCARB1,ZFYVE9,CLCN4,DNAJB5,SMG7,SV2A,SIDT2,MBNL2,LRRC23,ERBB2,CDKL3,C1orf61,GAB1,GABRA2,SIGLEC8,GNG4,LILRA2,GRM1,GRM7,MAP4,MAPT,NINJ2,ENPP2,PTCH1,RAB3A,RALGDS,TCP11L1,SYNDIG1,RASA3,SNAP25,ZNF415,SPTAN1,CEP68,SYT11,CAMSAP2,TNNT1,RBFOX2,TRO,PLPPR2,LAT2,SEMA3B,KCNAB1,PCBP4" Drug 5820_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "RALGAPA1,ARID1A,ADD2,MTUS1,PTCH2,ASTN1,ATP1A3,ATP2B2,NEURL1,AP4M1,QKI,CPS1,ENTPD4,FEZ1,ARHGAP24,ZNF337,GIT2,MAGI2,TAGLN3,MX1,NUCB1,PFKFB2,PIK3R1,PPARA,PPP5C,RASGRF1,KHDRBS2,GAL3ST4,RGS12,TMEM206,FNDC3A,ELMO2,SLC20A2,IFT122,TMCC1,KDM4B,KAZN,TBCEL,DOCK9,TNS1,LILRA4,VGF,PRDM2,KCNAB1,SMIM8,PHTF2,DPF3,RNF146" Drug 1893_UP Doxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADORA1,ANK3,SHTN1,ASCL1,ATM,FUBP1,CLDN10,REPS2,SOCS6,KIAA1549L,ARMC8,CRMP1,SOCS5,G3BP2,TMCC2,CEND1,ZNF589,FGFR1,ATP2C1,ERAP1,C1QL1,CRCP,PRRC2B,PCLO,GIT1,NAP1L1,NTRK2,PDE3B,MINDY2,RGS12,NUDT11,TMEM156,ATXN2,SLC1A7,LIMS2,DOP1A,RAP1GAP2,LARP4,STX1A,TCF7L2,TGFBR3,ZMYND8,TMPRSS5,VGF,CLIP2,ZNF24,MPPE1,NUP214" Drug 456_DN (-)-quinpirole hydrochloride; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADCY2,BIN1,ARNTL,BCL7A,SCARB1,LRRFIP1,SULT4A1,IFFO1,SDC3,ARHGAP32,DYNC1I1,ECM2,IRAK4,BSCL2,ERBB2,ETV1,VPS26C,EZH1,FOLR2,NSG1,GAD2,GDF9,GNG4,GUCY1A1,ATXN2L,VSIG4,L1CAM,STMN1,MMP17,ADAM22,OPCML,OPRL1,CDK18,NLE1,SMOX,MBOAT7,RGS4,PNMA8A,RPS6KA2,SYNDIG1,FNDC3A,PEX26,SLC8A1,CDK5RAP2,VAMP1,KCTD2,PARD3,TRPM2" Drug 4012_DN Pheniramine maleate [132-20-7]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "APC,SHROOM2,CDK10,DNAH17,SYNJ2,MAP7,ARHGEF2,CLU,DNAJB5,HOMER3,CNTNAP2,MFAP3L,RUSC2,SIDT2,MRNIP,STX2,ETV1,ZNF589,FER,TRAF3IP2,MSL3,GPER1,MUM1,SHISAL1,IL11RA,INPP5B,GIT1,PAK3,PBX1,SERPINI1,RALGDS,MYH14,IL17RB,ZFP30,SLC1A7,SLC6A9,KDM4D,ELMO2,WDTC1,LHPP,ARHGEF9,ARC,SYN2,ZKSCAN5,XRCC4,REEP1,SEMA3B,UBE3B" Drug 1436_UP Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABAT,WASF1,CAMK2B,RUNX1T1,RCBTB2,CHN2,ZFYVE9,CNTN1,DAPK1,NR1D2,FEM1B,KCTD3,BSCL2,EPB41L2,STX2,WAC,TUBB4A,KIAA1109,OLFM1,PRKAG2,AFF2,ATP2C1,OGA,HBS1L,ZMYND11,ERAP1,GLS,HMX1,NELL2,CNOT4,STRN3,PPP2R2B,CNNM2,PTPRN2,TTC13,RNASEL,GALNT10,ELMO2,ZHX3,SPART,SS18,CAMSAP2,TCF4,ZMAT3,TMPO,HIRA,XRCC4,SLC17A7" Drug 309_DN sulindac sulfone; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "NME5,BEGAIN,OGT,ANK2,PKP4,APBB2,ARHGDIG,CADM3,SYNJ2,CAPN3,ARHGEF2,CPS1,SPATA2,TMCC2,USH1C,KCNMB2,ERBB4,EXTL2,DLC1,FGFR1,PRKAG2,SUCO,SMC2,DISC1,GART,RUNDC3A,GRIA4,HSF2,ADAM22,NF1,NNAT,CAMKV,PLEC,PPP3CB,PRKAB2,MAPK3,PRPH,MTMR10,SUSD4,SUPT20H,ZKSCAN3,SNCA,TRIM2,TEX15,TNS1,TMPRSS5,TFIP11,EPM2A" Drug 5333_UP "Zidovudine, AZT [30516-87-1]; Up 200; 15uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "BRAP,ARHGDIG,ATM,ATP6V0A1,ADAM23,BCL7A,NRP2,CFLAR,ST3GAL5,SCARB1,CHRNB2,PDE4DIP,DAPK3,GIT2,ATN1,SIDT2,OPTN,NCALD,ZNF589,OLFM1,CAMSAP1,PRELID3A,GABRA2,GLYR1,NR3C1,GSN,AGBL5,MAP4,ZNF862,NEK1,NF1,NNAT,PBX1,PC,PDE3B,PLEC,CNNM2,RGS10,KCTD17,FOXRED2,SBF1,EPN2,SMTN,WWC1,TK2,ZBTB14,NDRG4,TFIP11" Drug 3869_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "AP2A2,AK2,APBB2,FAM131A,CDK13,NECTIN3,ARHGEF4,HDAC4,CTIF,RABGAP1L,DTNA,PHC2,HSD17B14,PLEKHO1,COQ7,ERCC2,KAT8,GPR153,GCNT2,SRCAP,POLL,ELOVL5,KCNH2,LMO2,MBD1,KITLG,NF1,LRP12,MBOAT7,NKAIN1,RAB3A,SLC1A7,SLC15A2,KIF13A,WDTC1,KDM4C,MAPK8IP3,STX1A,ATP11A,SEMA4A,MCF2L,EXOC7,KIAA1107,SMG6,CHST8,SLC44A1,PLPPR2,EPM2A" Drug 5683_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ASPHD1,ALCAM,APOC1,CLGN,HOMER3,SLC4A7,FAM169A,CTNND2,DCAF8,GIT2,MFAP3L,MED12,EPB41L1,CDKL3,ZNF589,ERAP1,TXNL4A,POLL,GPD2,HNMT,MAP4,SCAMP5,MITF,PDE3B,SLC25A23,PLXNB1,PRPH,PTCH1,TMEM231,MAPK12,FERMT1,EPN2,FAM214B,LIMCH1,ERC1,ELOVL4,SEPT8,EXOC7,ARHGEF12,AHCYL2,ATP13A2,AP4E1,BEX4,PARD3,TPM1,GDPD5,MPPE1,SMIM8" Drug 4534_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "MTUS1,AMT,KCNAB2,BCAS1,SEMA4G,ZSCAN18,NRP2,BAIAP3,CAMK2B,CD86,ASIC3,TAOK2,SH2B1,CRY2,VCAN,MAML1,MFAP3L,SRGAP3,EIF4G2,EPHA5,ETV1,GAB1,ERAP1,RND1,GPR22,GUCY1A2,HRH3,KCNN1,KIF5C,LIG4,ADAM22,NNAT,NPTX1,PDGFRA,PTPRO,RGS12,TMEM206,CCDC102B,MRAS,SLC2A5,HECW1,ZBTB43,NACAD,PHLDB1,VAMP1,ZEB1,CRB1,TMOD1" Drug 1972_DN Levodopa [59-92-7]; Down 200; 20.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "NDRG2,SPOP,KCNAB2,CASK,MARK4,PLAA,NIPBL,SMARCAL1,DCAF8,SIRPA,DBT,DCTN1,KIAA0753,TRAPPC9,FKTN,KIAA1109,SEC23B,SEMA4D,USP21,GPR153,OGA,SPIN1,LILRA2,DIDO1,NR3C1,ITGAV,KTN1,MBNL1,NFE2L2,NFYA,PFKFB3,SMIM7,EXOSC10,RETREG2,PCMTD2,ATXN2,SH3BP2,BCAN,ZNF430,MAPKBP1,SP2,MAPK8IP3,ZEB1,FRYL,TMPO,RBFOX2,WBP2,MFF" Drug 3337_DN Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ADRA1D,AP2A2,APBB2,BTRC,HAP1,ASIC3,VAX2,CNTN1,WHRN,NCOR1,CSF1,RBM12,SORBS3,HSD17B14,KAT8,SEMA4D,PRELID3A,DISC1,SEPT9,GCNT2,RAB30,ICA1,KCNJ5,VWA5A,MITF,CNOT4,SLC11A2,PLCD1,PRODH,TMEM104,RAD52,KCTD17,ZNF821,SGK1,SH3BP2,SYBU,PPP4R3A,SLC6A8,EMC1,IQSEC2,ELOVL4,PLCB1,SEMA4A,MCF2L,KIAA1107,SLC44A1,VIPR2,SYNC" Drug 2903_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ACTN2,BCAR3,APBB2,MARK4,CA8,ENTPD6,CLCN4,FAM149A,SIRPA,SV2A,NTM,SGSM2,DTNB,EEF1A2,EFNA3,KHDRBS3,GPR22,SPACA9,IL6ST,NEFH,NOS1,CDK14,EPN1,SLC25A23,ZNF426,LRP12,CEP41,PTPRH,PTPRN2,GAL3ST4,RFX2,MYH14,RPS20,CPEB3,SLC6A8,RBM26,VAMP1,TACR1,TCF7L2,RBFOX2,VAV2,CLIP2,SLC13A3,ZBTB38,SLC17A7,KCNAB1,PARP11,EPM2A" Drug 6075_DN Delsoline [509-18-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ALCAM,MRTFA,AMT,APBA2,KCNAB2,PPFIA3,CACNA1I,CA4,CAMK2B,PLEKHB1,SLC4A8,BAG4,CSF1R,LRIG1,PDE4DIP,TMCC2,DNM1,DUSP9,EML1,BAIAP2,SYT17,ALDH1L1,GCNT2,POLL,KCNMA1,NF1,PDE4B,MAPK7,PRODH,PTN,PTPRE,RAD51D,RGS10,WLS,SEC14L1,SH3BP2,SLC1A7,SNCA,KDM4C,KANK1,FAM168A,PARD3,CABIN1,TPM1,HIRA,VGF,VIPR2,MVB12B" Drug 6407_UP 3-nitropropionic acid; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "SLC12A5,AP2A2,ALAD,PPP4R4,ARHGEF1,RCBTB2,CNOT8,LHX2,IFFO1,CSF1,CHD5,PDE4DIP,TOX,EDIL3,MRNIP,RGS17,APC2,FGFR1,FYN,INPP5K,MSL3,GNG4,GRIK5,MMP16,NPR2,ODF2,CDIP1,PRKAR1B,PRPH,CNTLN,ZSCAN32,RAVER2,TCP11L1,PAQR6,RXRA,STUM,FUZ,BCAN,SNCA,KDM4B,ZHX3,COBL,ATP11A,TBCEL,CHST5,VGF,ZNF74,PARP6" Drug 5843_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.30E-03 1.00E+00 8.79E-03 1.00E-01 48 199 "ABHD6,ADD2,BIN1,APC,PPFIA3,APP,PDE8B,NCOA1,CFLAR,SLC25A14,NRG2,CSNK1E,SPOCK2,TMCC2,RCAN1,TNK2,DENND4A,FER,BAIAP2,FHL1,FYN,B4GALNT1,DISC1,GART,KIF3A,RNFT2,PLCD1,SEC61A2,KBTBD4,BTBD7,ZKSCAN3,COA1,SNCA,BEX1,DDN,LHPP,GSE1,TCF4,TRIM2,PSD3,TNS2,TK2,TRIO,XRCC4,SH3GLB2,MAP3K12,SMIM8,AAAS" Drug CID000446186 1i32 Stitch 1.30E-03 1.00E+00 8.80E-03 1.00E-01 34 129 "CASKIN1,EIF4G3,SYNJ2,SCARB1,CHGA,EDNRB,MRO,EIF4G1,EIF4G2,EIF1,SRRM1,ERBB2,ADGRV1,FECH,STAU2,RNPS1,TNRC6A,GOLGB1,GRK4,HPS5,ACOT7,MITF,XRN1,PTPA,CASC3,SOX10,STAU1,SMG6,TCF7L2,ZFP91,TSC1,TSC2,UPF3A,SCG2" Drug 5046_DN Pivampicillin [33817-20-8]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADRA1D,ALAD,LGR5,CDC14B,TPP1,HOMER3,ARMC8,VCAN,AK5,DLG3,SUGP2,MBNL2,STX2,ATP8A1,ZNF589,HBS1L,PRRC2B,GPR37,HSF2,IL6ST,INPP5B,L1CAM,MAPT,NF1,STRN3,PRKAB2,PTHLH,PEX5,SUGCT,RXRA,ASAP3,PPP4R3A,ELMO2,THSD1,ATP11A,KAZN,TCF4,KIAA0930,AHCYL2,ATP13A2,CABIN1,OSBP2,LMF1,TFIP11,MAP3K12,EVI5,KAT6A" Drug 6767_DN Leucomisine [17946-87-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "EPB41L5,CDK10,PLA2G4C,ALDH4A1,ATP6V0A1,SYNGR3,B4GALT6,SLIT2,ARMC8,CREM,AKAP12,ARHGEF10,DCAF8,ZNF337,SMG7,ELAVL3,RGS17,STX2,BAIAP2,CELF1,OGA,SRCAP,GLS,ACOT7,DHX35,INPP5B,MAPT,MBD1,NACA,NFYA,PCDH9,PDE3B,TMEM104,FAM184A,PPP4R3A,EPN2,SHANK2,SLC15A2,ARHGAP26,KAZN,TRPC1,LMF1,ZBTB38,REEP1,MARCH8,SMIM8,PHTF2" Drug 3903_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "NME5,PLA2G6,BIN1,APBB2,CDK13,SCARB1,B4GALT6,COL4A5,CTIF,SMG7,EXOG,EDNRA,HIPK3,PLXNC1,STX2,ERCC2,EZH1,ACSL4,SCML2,ZNF589,SCARA3,SEMA4D,ATP2C1,PRELID3A,OGA,HBS1L,SRCAP,GPER1,KCNJ3,MAOB,MMP17,NF1,NTRK2,PDE3B,PTHLH,RAB3IL1,RASA3,TSPYL2,EXOC7,SMG6,HEY1,TK2,FAM155A,PLPPR2,XRCC4,ZIC3,EMSY" Drug 3363_UP Doxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADD2,ADORA2A,NME5,TRMT9B,ATP1A2,ATP2A2,CA4,CAST,ARHGEF2,RAB33A,TPP1,NCOR2,AATK,ERBB2,F5,FHL1,FOXG1,FOLR2,GAD1,PRUNE2,GRB10,GRM7,KIFC3,MID1,MOBP,ZNF862,NELL2,NNAT,NOVA2,NPTX2,NTRK2,PCDHGC3,PLXNB1,TNPO2,PTAFR,KCNIP1,SALL1,SLCO1A2,LMO3,ZEB1,SZT2,TEK,TNS1,ADAMTS9,ITM2C,EPM2A,NUP214" Drug 6171_DN "Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADD2,AGT,C1QTNF3,CDC42BPA,ANK2,APOC1,PPP4R4,ALDH4A1,LDLRAD4,AP4M1,REPS2,TAOK2,RAB33A,PPP6R2,TBC1D5,NR1D2,DNM2,ST8SIA3,GAB1,SRCAP,PRUNE2,SOX21,MAP4,MATK,MEF2C,MYO7A,NDUFA5,SLC11A2,NUMA1,OMG,TREM2,NLE1,ST8SIA5,PLP1,BCAS3,FAM120C,RAB3A,ZFHX4,EPN2,SLC11A1,KDM4C,NSD1,AHCYL2,TMOD1,CDK20,FLRT2,FLRT1" Drug 2467_DN Omeprazole [73590-58-6]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "NDRG2,BIN1,BACH1,RAB33A,NMT2,IQCK,RCHY1,SMG7,RCAN1,HIPK3,EFNA3,MBNL2,ABI2,FHL1,ANKFY1,CELF1,SEPT9,GLS,RAB40B,EML4,NCKAP1L,TJAP1,ITGA7,JAK2,LSS,MAP4,MDM4,MEF2C,SCAMP5,GIT1,NFYA,SLC11A2,NUMA1,OGG1,PLCD1,SLC25A23,PRKCZ,CNNM2,PTPRN2,MSANTD2,CARF,SAFB,ZCCHC24,SS18,TCF7L2,PCBP4,SENP7" Drug 2799_UP Gramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADORA1,LTBP4,ASPH,LDLRAD4,CAMK2A,CAMK2B,CAMK2G,CBFA2T2,ZFYVE9,AKAP7,DUSP9,DMTN,FAM198B,CAMSAP1,ERAP1,GFER,GPR22,GRM8,IL6ST,KCNQ3,MAPT,MEF2C,MID1,PRKAR1B,MAPK8,RAB3IL1,KLHDC8A,RPS6KA2,SEMA6D,ARHGEF40,HECW1,TSPYL2,SPART,POPDC3,SEMA4A,EXOC7,KIAA1107,TBCEL,TRIM2,PSD3,GPR161,TK2,CABIN1,CA14,UCHL1,SYNC,KAT6A" Drug 2787_DN Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ABHD6,KIDINS220,AP2A2,SRPX,ATP6V0A1,CACNA1D,KYAT1,CCNT1,USP2,CNOT8,CSNK1E,GREB1,EDRF1,RABGAP1L,DTNA,EFNA3,NCALD,ZNF589,BAIAP2,HBS1L,STON1,CACFD1,ATXN2L,IL6ST,KCNJ3,KIF5C,LSS,MAP4,MAPT,MPP2,NUMA1,PDE3B,STRN3,PTPRE,FOXRED2,ZKSCAN3,RBM34,TROVE2,THSD1,NCDN,PLCB1,AHCYL2,TMOD1,SF1,REEP1,EMSY,EPM2A" Drug 7098_DN 0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "RALGAPA1,PPFIA3,ATM,BCL7A,ZFYVE9,HOMER3,WHRN,SDC3,DCAF4,ZFYVE16,GIT2,RABGAP1L,APH1A,EPB41L2,ERBB2,ETV1,F3,FAM49B,TRAF3IP2,SRCAP,FERMT2,GUCY1B1,DIPK1A,MAP4,MDFI,MITF,NPR2,SETD4,ARHGEF10L,MCMBP,AMBRA1,PEX26,RAB3GAP1,ZBTB43,TSPYL2,DIP2A,SYNE2,ARHGEF9,EXOC7,PDLIM2,TBL1X,MGRN1,TCF7L2,NR2C2,HIRA,EMSY,ACTR3B" Drug 4612_DN Capsaicin [404-86-4]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "TRMT9B,APP,ASPH,ADAM15,CFLAR,SYNJ2,SPAG9,QKI,ARHGAP32,DAPK3,HP1BP3,RUSC2,SLC12A6,RGS17,VPS26C,ZNF589,BAIAP2,FHL1,ANKFY1,SIGLEC8,INPP5K,C1QL1,MSL3,GNAS,DHX35,DIPK1A,MBD1,NDP,NFYA,NUCB1,PLCD1,PLEC,RC3H2,LRP12,PEX5,GTDC1,TMEM156,SH3BGR,AMBRA1,ST5,ARHGEF9,FBXW11,TCF4,TMEM121,NSD2,EVI5,RNF146" Drug 5440_DN Imipramine hydrochloride [113-52-0]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "SLC12A5,NME5,SEMA6A,ALCAM,BRINP2,CFLAR,BAIAP3,CBFA2T2,FADS2,SIPA1L1,CNTNAP2,GIT2,MFAP3L,SGSM2,SUGP2,NCALD,ACSL4,SEMA4D,MPP6,OGA,MALT1,RAB30,MSL3,PRRC2B,INPP5B,KCNJ3,MPP2,ADAM22,NDUFA5,NTRK2,SERPINE2,PRKAR1B,FBXO11,SLC1A7,SLC20A2,EMC1,CLASP2,PLCB1,EXOC7,ARHGEF12,AHCYL2,TGFBR3,TMOD1,TRPC1,KLC2,SPHK2,EVI5" Drug 4174_DN Decamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "C1QTNF3,LTBP4,AMPD3,RUNX1T1,CACNA2D2,DNAJB5,WHRN,NOS1AP,SRGAP3,DTNA,DYRK1A,ELN,DMTN,EZH1,SEPT9,GPER1,ADAMTS13,DHX35,INPP5B,TM6SF1,ADAM22,BCO1,MYT1,NEUROD1,NF1,NOS1,STRN3,TMEM104,C1orf54,KCNIP1,SBF1,SH3BP2,CPEB3,RPH3A,SLC2A5,FAM214B,SNAP25,TNIK,DOK5,ZHX3,POPDC3,KAZN,TBCEL,RPGRIP1L,PARD3,VGF,ZIC3" Drug 4312_DN Benfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "RALGAPA1,MTUS1,PLA2G6,CDC42BPA,ASPH,ATM,CFLAR,SPAG9,KRIT1,SRSF11,ABI3BP,FCF1,ING4,FER,FAM49B,ZNF44,SPIN1,AGFG1,IFI16,IL6ST,MAP4,N6AMT1,NDP,NFIX,NUMA1,ZNF426,STRN3,RC3H2,PKN2,SLC25A36,KIRREL1,SEC14L1,CCDC88A,BTBD7,ARHGAP26,SS18,TBL1X,EHBP1,TCF4,TRIM2,PSD3,DICER1,TMPO,SF1,ZBTB38,WNK1,PRDM2" Drug 6457_UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "SYN3,ACTN2,SEMA6A,SYT13,CDC42BPA,GAS7,APLP1,MARK4,N4BP2L1,SLC16A4,CLGN,WHRN,ARHGEF10,ATRNL1,DAPK1,SRGAP3,ATN1,ST8SIA3,EFS,OLFM1,NSG1,ERAP1,GFER,GPM6B,STON1,HMGCR,MAPT,NDUFA5,CNOT4,OPCML,CDK18,GON4L,RAB5B,TCP11L1,EMID1,ZFP2,FAM214B,SNCA,ZHX3,EMC1,TRIM2,HIF3A,SPX,CHST5,SLC26A10,SLC30A3,WNK1" Drug 4828_UP Simvastatin [79902-63-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADD2,ADORA1,ADORA2A,NME5,C1QTNF3,SYT13,APC,GAS7,CFLAR,DCAF4,SNPH,DBN1,DTNA,EDNRB,DLC1,BAIAP2,TOX3,PCLO,KLF12,KCNJ3,LSS,MAN2A2,MSI1,CDK18,CDK14,PIK3CD,EPN1,PLTP,PRKAR1B,C1orf54,RGS12,FBXW7,ASAP3,SMTN,PKNOX2,SLCO1A2,DOK5,ATP10B,INKA2,SYN2,SYT5,EXOC7,PCDHGA10,PSD3,OBSL1,HEY1,WNK1" Drug 6272_DN Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "PPFIA3,RIPK1,KIF1A,C5,UBE2L6,SOCS6,PLAA,ARMC8,CSNK1E,DZIP3,DCAF8,GIT2,C2CD2L,PARD6A,DLG3,CELSR3,CDKL3,EZH1,EFCAB2,FAM49B,GNG4,GRB10,MAP4K5,HSD17B1,NAP1L1,NASP,NUCB1,OGG1,PDE3B,PLXNB1,TMEM231,BSDC1,ZDHHC4,WLS,FERMT1,KBTBD4,SLC20A2,CDK5RAP2,PBLD,SEPT8,ASTN2,TACC1,TBL1X,TCF7L2,CLASP1,KAT6B,ZMYND8" Drug 4795_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "KIAA1324,AMPD3,CDC42BPA,CDK13,MARK4,ASPH,BAIAP3,CBFA2T2,AATK,CSF1,SPOCK2,MAGI2,RABGAP1L,KBTBD11,EFNA3,FAM13A,TNK2,DMTN,F5,CACNG3,AGAP2,GLS,GNG4,GRB10,PTGDR2,KLF12,SYNPO,MBD1,ADAM22,MX1,NF1,NTRK3,P2RY1,NLE1,EPN1,PTPRE,C1orf54,LIMS2,SMARCD3,WDTC1,IZUMO4,SAMSN1,SYN2,GPR161,BEX4,WIPF1,ZNF74" Drug 4961_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "PPFIA3,SEMA4G,ALDH7A1,SCAPER,LDLRAD4,CAMK2B,NEURL1,ARHGAP33,SULT4A1,HOMER3,DAPK3,MFAP3L,TMCC2,USH1C,SIDT2,EFNB3,PLXNC1,MTSS1L,ZMYND10,ZNF589,CAMSAP1,FHL1,LYVE1,ADAMTS13,GRM8,GUCY1A2,HRH3,ATXN2L,SYNPO,KCNH2,MAP2,NEUROD1,NNAT,CNOT4,CDK14,RETREG1,MTRF1L,NLGN1,SLC1A7,SLC8A2,KDM4B,ARC,SYT5,MCF2L,ICAM5,PARD3,TNS1" Drug 3785_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "RASL11B,CADM3,RGS9,CAMK2B,CDO1,KIAA1549L,SLC24A2,CNTFR,MAGI2,SRGAP3,ING4,FABP7,FLT1,GNAO1,GRM8,GSTM5,IGF1,IL6R,KIT,KPNA5,MGAT3,MMP16,NUMA1,PBX1,CDK18,PPP1R1A,DCHS2,GDPD2,PTN,RET,ABLIM3,PREX2,SLC2A5,RIMS1,ZC3H13,NPAS3,SPART,ATP10B,MCF2L,KLHL4,DOCK9,OBSL1,WIPF1,MAP3K12,EVI5,PARP6,JPH3" Drug 3861_DN Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "DOC2A,CDC42BPA,APBB2,APC,DNAH17,MARK4,BAIAP3,CBFA2T2,ARHGAP33,TAOK2,AKAP7,ZNF804A,DNM1,EFNA3,ING4,ELN,FGF12,FGFR1,EFCAB2,PDLIM5,B4GALNT1,SRCAP,GFER,GLS,ATXN2L,ITPKB,ZNF862,NRGN,PDE4A,PFKFB2,PLEC,SNRK,RAD52,ZDHHC14,SH3BP2,SNCA,WDTC1,TROVE2,TNS2,HEY2,MICAL1,LAT2,ZNF74,NDRG4,MAP3K12,PRDM2,HPS4" Drug 4623_DN Hymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "APC,APP,PDE8B,ASTN1,ATP2B2,SYNJ2,LDLRAD4,CFAP410,ABCG2,CREM,NCOR2,DZIP3,GPRASP1,RUSC2,SGSM2,RCAN1,DTNB,MBNL2,RGS17,KIAA1109,ANKFY1,DENND2A,SIGLEC8,CACFD1,TJAP1,DIPK1A,NEK1,OCRL,PALM,SYTL2,ZSCAN2,TMEM231,FAT4,RAP1GDS1,DCUN1D2,KIRREL1,RBM34,IQSEC2,TAB2,TCF7L2,TIAM1,TK2,RBFOX2,NSD2,EMSY,VPS35L,MPPE1" Drug 1217_DN chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "AMT,CDC42BPA,MADD,CA12,CDC25B,SOCS6,FADS2,NCOR1,OSBPL3,ARHGEF4,ARHGAP32,C2CD2L,DLG3,TUBD1,ETV1,EZH1,FCGRT,ZNF589,DPYSL4,GAD1,AHDC1,PRRC2B,MAN1B1,ARHGAP19,PCDH9,PDE4B,MBOAT7,PRPH,RIPOR1,RAD51D,ZDHHC14,ARHGEF10L,SBF1,PEX26,SMTN,SMARCC2,STX1A,KAZN,TCF7L2,CLASP1,ARHGEF12,KCTD2,HIRA,TRIM9,MAP3K12,PLSCR4,NUP214" Drug 3521_DN Phensuximide [86-34-0]; Down 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "KIDINS220,AP2A2,AK2,PLA2G6,C1QTNF3,SRPX,APBB2,APC,PPFIA3,MARCH3,RASL11B,ATM,CFLAR,SCAPER,SOCS6,B4GALT6,VAX2,HOMER3,CHD1L,CRY2,CTH,DAPK3,PHF20L1,ZNF589,FHL1,HBS1L,NR3C1,HNMT,MAPT,MITF,CNOT4,NPTX1,PALM,PTPA,PPP3CC,CNNM2,ELOVL2,WLS,BTBD7,ZCCHC24,UNC5B,ELOVL4,PHLDB1,POPDC3,TMOD1,WNK1,SSPN" Drug 954_UP (+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "NDRG2,C1QTNF3,LTBP4,EPB41L5,BCL7A,CFLAR,MTMR2,CACNA1A,NFS1,MAGI1,ZFYVE9,RAB26,PHF14,ARHGEF4,SLC12A6,CELSR3,IRAK4,FGFR1,FAM49B,GRB10,IL11RA,KCNK1,MBD1,NRCAM,PFKFB2,PPP5C,MAPK8,ATG16L1,EMID1,PAQR6,ATXN1,ZFP2,ZNF821,PEX26,PPP4R3A,SMTN,SLC6A8,ELMO2,MAPKBP1,VPS13A,RPGRIP1L,ARHGEF12,TMOD1,CDK20,RUNDC3B,MICAL1,EVI5" Drug 4001_DN Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ASIC1,BIN1,APP,ARRB2,ALDH4A1,KIF1A,DNAJB5,RAB26,HOMER3,SH2B1,ARHGAP24,RUSC2,ATN1,DTNA,PLXNC1,SORBS3,COQ7,SCARA3,CINP,B4GALNT1,SEPT9,GCNT2,GFER,MSL3,POLL,GUCY1A2,SHISAL1,MN1,NDUFA5,FA2H,CNNM2,RALGDS,RGS10,PEX26,SLC6A9,TSNAXIP1,SS18,MAPK8IP3,ARC,TK2,CABIN1,MICAL1,WIPF1,XRCC4,REEP1,SEMA3B,MPPE1" Drug 7086_UP PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "APLP1,ARHGAP5,ARNTL,ARRB2,ATM,CFLAR,ST3GAL5,SCAPER,RAB29,NFS1,CLCN4,FADS2,NIPBL,PREPL,GIT2,DBT,COQ7,ERCC2,RACK1,TESK2,FAM49B,DENND2A,GART,CNTRL,SLC2A6,IFI16,INPP1,MDFI,SMIM7,ZNF426,CDIP1,MED1,SAMD9,SNRK,TMEM260,NUDT11,ASRGL1,ITSN1,ST6GAL1,FNBP1,ZBTB43,SYT1,ATP11A,ARHGEF12,TK2,HPS4,SMIM8" Drug 7059_DN "Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ACTN1,MTUS1,CDC42BPA,ANK3,APBB1,ALDH4A1,CCNT1,TAOK2,AKAP7,NRG2,PDE4DIP,KIAA0513,DBT,SORBS3,LRRC23,SEMA4D,POMT1,CINP,ZMYND11,GBX2,CRCP,PADI2,SCIN,IL11RA,MAP2,MEF2C,ADAM22,PPP5C,MAPK7,PRPH,PTX3,TMEM231,SH3TC2,SEC14L1,FUZ,DZIP1,TMCC1,SPTB,RAP1GAP2,SEPT8,TTBK2,RGL1,JMJD6,EHBP1,SYNE1,TNS1,PHTF2" Drug 6195_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "RALGAPA1,SEMA7A,CACNA1I,CACNA1G,BTRC,TMEM59L,VAX2,PDE4DIP,DZIP3,SNPH,DLG3,ATN1,DSCAM,SEZ6L2,OPTN,MBNL2,EGR3,C3orf18,VPS13B,F5,FGFR1,FHL1,ZNF44,GABRA5,FERMT2,GPD2,PCLO,KCNJ5,ZNF862,CNOT4,NPPA,OPRL1,PCSK5,PDE4D,SERPINI1,CCSER2,GALNT10,ASAP3,CNKSR2,PALLD,KDM4B,ZCCHC24,CDK19,SS18,CRB1,UBE2H,PRDM2" Drug 2185_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "GRAMD1B,ATP2A2,ADAM15,CFAP410,CBR1,SCARB1,CLGN,HOMER3,COL9A2,CSF1,FEZ1,ZFYVE16,ZNF337,RCAN1,OGA,HBS1L,SRCAP,TXNL4A,POLL,PRRC2B,SLC2A6,MUM1,KPNA5,LSS,MYT1,ENPP2,CCSER2,TMEM104,ZSCAN32,RAB3IL1,CEP97,RAP1GAP,TCP11L1,SBF1,CCDC88A,ELMO2,TMCC1,KDM4B,SS18,NSFL1C,SIN3B,DMXL2,TCF7L2,ZMYND8,NSD2,LAMP5,EVI5" Drug 4133_UP "Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ASPHD1,ACTN2,APAF1,GAS7,SYNJ1,CBFA2T2,ZFYVE9,HAPLN1,CRY2,DCAF4,DAPK3,ATN1,EGR3,EIF5,KCNMB2,IGSF6,DLC1,KIAA1109,GAB1,GAD1,NEU3,GRIK5,GSTM5,ATXN2L,KLF12,ACOT7,KCNJ3,KCNMA1,MIA2,ADAM22,NF1,CLDN11,GPR85,PLCD1,PACSIN1,RAB3IL1,RGS10,PNMA8A,DOCK10,SLC11A1,ZNF415,SP4,KIAA1107,SLC35G2,HIF3A,FAM155A,SSPN" Drug 2068_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "MTUS1,CDC42BPA,ARNTL,CDK13,ASPH,STX16,MTMR2,SPAG9,CDH2,CHM,CLCN4,CLTB,QKI,BAG4,CREM,GIT2,HIPK3,FCF1,EGFR,MBNL2,ING4,PLEKHO1,DENND4A,EZH1,WAC,FHL1,ZMYND11,SIGLEC8,GCNT2,MAP4,MEF2C,ZFYVE21,PPP5C,MAPK8,RAD51D,MYH14,SS18,SEMA4A,TBCEL,PSD3,ARHGEF12,RBFOX2,ZKSCAN5,UBE2H,UGT8,MAP3K12,SENP7" Drug 6613_DN Theobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "APP,DNAH17,MYRF,CFAP410,CACNA1A,MAP7,SCARB1,PLEKHB1,CLCN4,DNAJB5,PICK1,CPS1,CREM,ABCG1,CSF1R,CTIF,EGFR,HSD17B14,PLEKHO1,ANKMY1,C1orf61,FYN,TRAF3IP2,INPP5K,CRCP,GPD2,SPACA9,HLF,MBD1,AFDN,MMP16,CNOT4,PRKAR1B,PTPRE,FAM120C,RPS6KA2,SH3BP2,SLC14A1,WDTC1,MAPK8IP3,RPGRIP1L,CRTC1,ZMYND8,ZNF711,WNK1,KAT6A,PHTF2" Drug 6575_DN Gly-His-Lys acetate salt; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADORA1,KIDINS220,KIAA1324,APOC1,PPFIA3,CDK10,MADD,BACH1,AP4M1,CHRNB2,ABCG1,DCAF8,SMG7,NR1D2,EPB41L1,EPB41L2,F5,PTK2B,ZNF589,USP19,GLS,GNG4,MAN1B1,INPP5B,MAP4,NLE1,SLC25A23,PLTP,MAPK3,RAD51D,TRIM68,PEX26,SMTN,RBM34,KDM4C,EXOC7,PDLIM2,SIN3B,BHLHB9,TMPO,PARD3,CABIN1,ZKSCAN5,PLPPR2,EMSY,PRDM2,SMIM8" Drug 5932_UP "rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ABR,LTBP4,ZBTB10,N4BP2L1,SYNJ2,IL33,RAB33A,RAB26,WHRN,CHD1L,ABCG1,VCAN,FRMPD4,ING4,STX2,ETV1,OGA,TMEM8B,ATP8A2,INPP5K,POLL,GPR19,STON1,DIDO1,SPACA9,BACH2,HNMT,MT1M,NF1,CNOT4,PENK,PRPH,PTHLH,TMEM231,SUPT20H,ASAP3,CDK19,NXT2,CEP68,TAL1,KIAA1107,TNS1,TRIO,WIPF1,HPS4,PLSCR4,RNF170" Drug 3213_UP Colchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "NME5,ASTN1,ALDH7A1,BTRC,CALB2,CDC42,KIAA0513,RASSF2,ARMCX2,DMPK,ATN1,DTNA,PLXNC1,SPEG,ETV1,FGFR1,PRELID3A,GRM7,HAS2,IRF8,KCNN1,LSS,AFDN,GIT1,NF1,PALM,PCSK5,PFKFB2,SPATA6,RGS12,KCTD17,SEMA6D,SCN2B,PPP1R9A,ASAP3,SLC2A5,PEX26,SMTN,LIMS2,SLC6A8,PALLD,PSD3,GPR161,TLR4,R3HDM1,TRPC1,VSNL1" Drug 3166_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "MRTFA,DOC2A,ATP6V0A1,BCL7A,CACNA1D,CAMK2G,FAM189A2,SH2B1,ABCG1,PARD6A,KBTBD11,HSD17B14,EPB41L2,STX2,EZH1,SEMA4D,GPR153,ZNF44,GALC,USP19,RNFT2,HNMT,KCNJ3,MATK,NFYA,PDE3B,SLC25A23,MINDY2,LRRC49,PTPRE,RIPOR1,BTBD7,EMC1,IQCE,TCF7L2,CRTC1,CHST8,ZNF34,NPL,ZKSCAN5,HIRA,RPRM,VIPR2,ZNF74,HPS4,EPM2A,UBE3B" Drug 3870_UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "KIAA1324,ALCAM,APBB2,APC,GAS7,ATM,ADGRB1,RHBDL1,CCK,ARHGEF1,CSF1,RUSC2,EFNA2,EFNB3,VPS13B,USP19,GRM1,RASSF8,ICA1,ITPKA,MAPT,MATN3,MMP16,ADAM22,NF1,OMG,PPARA,CEP41,PTAFR,ZSCAN32,RGS12,RPS6KA2,EMID1,RPS20,ZFP2,SH3GL3,DOCK10,IZUMO4,EMC1,ROBO3,TBCEL,TCF4,PCDHA5,HIRA,LAT2,XRCC4,KAT6A" Drug 2067_UP Ursolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ALK,TRMT9B,APBB2,ALDH4A1,MPDZ,MYRF,CACNA1A,CARS,LARGE1,CHI3L2,SLC4A8,CSF1,DZIP3,BRINP1,DPH1,EDNRA,ING4,MTSS1L,EZH1,ATP8A1,BAIAP2,OGA,SIGLEC8,DISC1,SRCAP,C1QL1,MSL3,SHISAL1,KPNA5,NUCB1,RETREG1,RAB3A,RAB3IL1,ZCWPW1,FBXW7,TRAPPC13,SATB1,SUPT20H,KDM4C,CEP68,DIP2A,FBXW11,SMG6,RPGRIP1L,AHCYL2,ZNF24,SPHK2" Drug 6921_UP "H-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADCY6,NME5,ALAD,LTBP4,ARHGEF7,LARGE1,SOCS6,CLCN3,NMT2,OSBPL3,SGSM2,EIF4G1,EML1,TBC1D16,FYN,SYT17,GLRB,PCLO,NR3C1,RASSF8,AGFG1,IL6ST,JAK2,KCNK1,MMP16,NAP1L1,CDK14,MED1,PRKACB,PRKAR1B,RALGDS,SEC14L1,ELMO2,ZHX3,ZNF302,ANKRD12,ROBO3,EXOC7,TBL1X,TGFBR3,NR2C2,TRIO,HIRA,SF1,ZBTB38,WNK1,SNX27" Drug 4111_DN Phenacetin [62-44-2]; Down 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADRA1D,PLA2G6,MRTFA,EPB41L5,APOC1,PDE8B,ATM,KIF1A,CFLAR,ABI3BP,GREB1,JAKMIP2,HP1BP3,TRAPPC9,DRD1,CELSR3,ING4,LRRC23,ATP8A1,ZNF589,FGFR1,FHL1,FAM49B,DISC1,SEPT9,GLYR1,GNAS,NPR2,NLE1,LRP12,MAPK7,MAPK8,TMEM104,PLPPR1,PTN,TCP11L1,ANKRD6,ABLIM3,SNCA,ATP11A,ARHGEF12,TNS2,VGF,UPF3A,SEMA3B,KCNAB1,UBE3B" Drug 4221_DN Tolnaftate [2398-96-1]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ADCY6,PLA2G6,CFLAR,ST3GAL5,SPAG9,QKI,BAG4,SLITRK5,CTH,ARHGEF4,CNIH3,PLPPR4,MBNL2,DMTN,EPHA5,SPEG,ETV1,ANKMY1,POLR1B,PDLIM5,DENND2A,ZMYND11,GLI2,SHISAL1,IL6ST,DIPK1A,JAK2,TAGLN3,NDP,PIK3R1,RETREG1,RC3H2,SNRK,ZSCAN32,PTPRN2,RAD51D,FUZ,FBXO11,ST6GAL1,NLGN1,LIMCH1,ARHGEF12,ZNF34,WIPF1,NSD2,KCNAB1,EPM2A" Drug 3969_DN 0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "LTBP4,MRTFA,BIN1,PLA2G4C,BRINP2,BMP7,SGCE,CSF1,RUSC2,DMPK,EDNRA,RASGRP1,EFNB3,EGR3,RASGRP2,PIPOX,CEND1,F5,KIAA1109,CAMSAP1,AGAP2,FAM49B,SRCAP,GNG4,GPR37,GRIK5,ATXN2L,KCNMA1,KCNN1,VWA5A,NPR2,CDK18,PDE1C,PFKFB3,MAPK7,SIDT1,RPH3A,UNC5B,PEG10,IQSEC2,TROVE2,POPDC3,CRTC1,DICER1,VGF,LAT2,SEMA3B" Drug 2793_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "BTRC,CA4,CACNA1D,USP2,ARMC8,CSF1,CSF1R,SPOCK2,EFNB3,LRRC23,FAM198B,ZNF589,KIAA1109,FGFR1,SEMA4D,ELOVL5,HNMT,LMO2,SMAD1,MIA2,MOBP,MX1,NEK1,NF1,SLC11A2,NTRK2,PIK3CD,NLE1,LRP12,PPP2R2B,CEP41,PRKAR1B,RAD52,DCUN1D2,FOXRED2,SH3BP2,SIRT2,LIMCH1,EMC1,CEP68,ATP11A,SYNE1,SLC44A1,TMOD1,TPM1,VGF,KCNK12" Drug 1707_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "MTUS1,C1QTNF3,LTBP4,DGKD,FAM131A,CDK13,ALDH4A1,RIPK1,SYNJ2,CA12,HIP1R,PLEKHB1,WHRN,CRY2,CSF1R,DAPK3,DNM1,SLC12A6,OPTN,CDKL3,VPS26C,GAA,AHDC1,NR3C1,RNFT2,INPP5B,KCNH2,MAP4,PDE3B,RETREG1,PLEC,PPP3CA,PRKAR1B,APTX,RAB5B,DCUN1D2,SYBU,FAM214B,SLC20A2,WDTC1,EMC1,FCHO1,CEP68,IQCE,TCF7,MICAL1,UBE3B" Drug 4744_UP Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "RALGAPA1,ASIC1,BEGAIN,APBA2,KCNAB2,BRINP2,ADGRB2,GYG2,CDH2,CHGA,CHM,CLCN4,NECTIN3,CRY2,SNCAIP,CSF1R,SV2A,KBTBD11,TRAPPC9,DTNA,HIPK3,FAM13A,VPS13B,MTSS1L,ZNF589,GPR153,GAD1,ERAP1,SRCAP,TJAP1,KCNH2,MYT1,OPCML,PLCD1,MINDY2,MAPK7,PLPPR1,PTHLH,EMID1,RPH3A,TSPYL2,ATP10B,SYP,THBS4,THRA,MKRN3,SYNC" Drug 6518_DN Enilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ASIC1,ABHD6,BIN1,APC,APLP1,SEMA4G,C5,REPS2,VAX2,AKAP7,WHRN,BAG4,CREM,HINFP,SOCS5,PDE4DIP,FAM169A,SDC3,DBT,LYPD1,DNM2,RBM12,EGFR,C1orf61,B4GALNT1,GRIK5,ELOVL5,IL6R,RIPOR1,TRAPPC13,ZNF821,SUPT20H,KIF16B,SMTN,ZC3H13,SS18,NXT2,SEMA4A,EXOC7,AHCYL2,TJP1,CDK20,SSBP2,UBTF,XRCC4,ZBTB14,MAP3K12" Drug 3828_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.32E-03 1.00E+00 8.84E-03 1.01E-01 47 194 "ASPHD1,ADORA2A,AK2,APBB2,APC,APOC1,ATM,CFLAR,KYAT1,CBFA2T2,FOXN3,DNAJB5,AKAP7,RCHY1,SH2B1,CTNND2,DMPK,LRRC23,ZNF589,GPR153,HBS1L,SRCAP,GFER,HNMT,MPP2,ADAM22,LYRM9,NDUFA5,PLCD1,PRODH,SNRK,ZSCAN2,RAD52,TCP11L1,SBF1,SEC14L1,ITSN1,BTBD7,LIMCH1,SPTAN1,ASTN2,EXOC7,TGFBR3,PLPPR2,LAT2,ZFP37,SSPN" Drug ctd:C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid CTD 1.32E-03 1.00E+00 8.85E-03 1.01E-01 123 605 "NDRG3,ADRB2,AK2,AMH,APAF1,PDXK,IGDCC4,DYNLL1,ALDH4A1,ATP2B2,CFLAR,BMP7,CA4,CACNA1B,CAMK2A,CAMK2G,CANX,NFS1,CCKBR,METTL6,SEPT7,CCPG1,JAM2,ARHGAP22,DNAJB5,SULT4A1,WHRN,IFFO1,BAG4,NCAN,CNTNAP2,ARHGEF4,ECE2,CENPL,RASSF2,DAPK3,RUSC2,ZC3H11A,KBTBD11,DMPK,SLC29A4,PDCD6IP,TMTC1,SIDT2,EGFR,MBNL2,EIF4G2,RASGRP2,RABEPK,EFS,F3,OLFM1,POLK,CGREF1,ST6GALNAC3,GATM,PLCD4,GRIK5,KIF3A,ZHX1,MAN1B1,GABARAPL2,HMGCR,HSP90AA1,CELF5,ITGAV,ITPKA,KCNJ4,KIT,LIFR,FGFBP3,LSS,NACA,NEFH,NF1,PC,PCDHGC3,PRTG,GNG2,TMEM38A,GPSM2,HMGCLL1,RC3H2,EPB41L4B,PPP2R2C,NKAIN4,APTX,MTMR10,ELOVL2,TUG1,PID1,SLC6A15,ZMAT4,RPRD1A,SETD5,FBXW7,RTKN,MRAS,CHD9,ZNF365,LIMCH1,PALLD,SCN3B,SOX11,CAND2,SRPK2,STOX1,TAF9,TRIM2,DOCK9,AHCYL2,VWCE,TEK,ATP13A2,HHIP,TRH,KCNE5,TSC2,RPRM,SLAIN1,WIPF1,NSD2,SENP7" Drug CID000005566 trifluoperazine Stitch 1.33E-03 1.00E+00 8.90E-03 1.01E-01 72 325 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1B,MYH7B,ANXA7,SPTBN4,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA2D1,CALM1,CAMK2B,CAMK2D,KRIT1,RGN,LRBA,CHRM1,CHRNA4,CHRNB2,MYL6B,CALY,DRD1,F3,PTK2B,ACTL6B,ATP2C1,HTR2A,MYLK2,KCNH2,KCNN1,KCNN2,KCNN3,MAP2,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,NOS1,PDE1A,PDE1C,PDE1B,ABCB1,PHKG1,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MYH14,S100B,MYO18A,SPTAN1,SST,SYN1,SYN2,SYP,ACTR6,TNNT1,CABIN1,TRH,NUP214" Drug 5254_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.33E-03 1.00E+00 8.93E-03 1.02E-01 46 189 "PLA2G6,APC,ARRB1,ADAM15,SYNJ1,RAB28,DAPK3,DBN1,RABGAP1L,NR1D2,RCAN1,FCF1,MBNL2,ING4,EPB41L2,RRAGB,FGF13,FGFR1,CAMSAP1,IQCG,PDLIM5,GNAS,STON1,RASSF8,KCNJ3,MBP,MDM4,KITLG,NUMA1,PDE3B,PLEC,FAM184A,SLC15A2,WDTC1,KDM4C,ZC3H13,STX1A,PLCB1,PCDHA5,TMPO,RBFOX2,ZBTB14,MPPE1,EPM2A,PHTF2,SENP7" Drug 7206_UP Ivermectin [70288-86-7]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-03 1.00E+00 8.93E-03 1.02E-01 46 189 "AK2,APLP1,DDO,PLA2G4C,BAIAP3,CA4,CACNB2,ARHGEF2,CDH10,CLGN,NRXN3,BAG4,OPTN,EGR3,DLC1,BAIAP2,FHL1,FYN,GCNT2,SRCAP,GRB10,GRM1,CELF3,RASSF8,SYNPO,ICA1,ITPKB,MGAT3,MIA2,KITLG,AFDN,MSI1,EMID1,RYR1,FRMPD1,SYBU,WDTC1,KIF21B,KDM4C,VAMP1,ARHGEF9,PCDHGA10,TMOD1,PRDM2,PHTF2,RNF170" Drug 1832_DN Isoflupredone acetate [338-98-7]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.33E-03 1.00E+00 8.93E-03 1.02E-01 46 189 "ABHD6,MTUS1,ADGRF5,APBB1,APOC1,SYNJ2,NIPBL,SLC4A7,CSF1,CSNK1E,DAPK3,LYPD1,EN2,COQ7,SCML2,SEMA4D,CGREF1,FYN,INPP5K,GBX2,USP19,HTATSF1,FERMT2,GPER1,ICA1,KIFC3,MITF,ZNF862,NEK1,ODF2,PDE4B,GRAMD1C,CNTLN,PTHLH,GAL3ST4,RGS4,FNBP1,NCDN,VPS13A,DNMBP,EHBP1,ZEB1,VAV2,PRDM2,NAV3,URM1" Drug 2832_UP Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.33E-03 1.00E+00 8.93E-03 1.02E-01 46 189 "ADORA2A,NME5,PPFIA3,ATM,NRP2,CFLAR,CACNA1I,FOXN3,WHRN,RASSF2,DBT,TMCC2,EXOG,EFNB3,SUGP2,FGFR1,OGA,MSL3,TDRKH,EML4,IL6ST,INPP1,KCNH2,MITF,AFDN,ZNF862,PLCD1,PACSIN1,MAPK8,C1orf54,RGS4,RGS12,FBXW7,KCNIP1,PPP1R9A,ASAP3,ATP10B,INKA2,PLCB1,WSCD1,TCF7L2,AP4E1,ZMYND8,PLPPR2,WNK1,PARP11" Drug 1225_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.33E-03 1.00E+00 8.93E-03 1.02E-01 46 189 "GRAMD1B,SEMA4G,ALDH4A1,STX16,MPDZ,NRP2,BTRC,EPS15L1,CRY2,CTH,EDRF1,GIT2,KLHL3,ARNT2,EZH1,TMEM164,RND1,DIDO1,MMP16,NACA,NAP1L2,NFYA,OXTR,SMOX,POLG,MED1,WDR25,PTHLH,TMEM231,SH3TC2,RGS4,RXRA,HSPA4L,ITSN1,SLC11A1,BTBD7,SLC20A2,PDZD2,RAP1GAP2,MAPK8IP3,ASTN2,TBCEL,TRIM2,CABIN1,UGT8,SEMA3B" Drug ctd:D002112 Calcifediol CTD 1.34E-03 1.00E+00 8.97E-03 1.02E-01 26 91 "AQP4,ATP1A1,ATP1A3,CANX,CDH2,CLTA,DPP6,RASGRP1,DCTN4,CSPG5,GABBR1,NCKAP1,CPLX2,GFAP,GLUL,IGF1,KLC1,MAP2,MOBP,PDPK1,PSAT1,PPM1B,MAPK9,SNRK,SLC1A3,SYT1" Drug 7074_UP MS-275; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.34E-03 1.00E+00 9.00E-03 1.02E-01 45 184 "MTUS1,ADGRF5,BRINP2,SLC4A4,ST3GAL5,SYNGR3,CLU,ABCG1,DZIP3,PLPPR4,RGS17,FGF13,FYB1,FYN,SYT17,GRB10,KIF5C,MAP2,MAPT,MEF2C,SCAMP5,MMP16,TAGLN3,PDE4B,ENPP2,SERPINI1,PMP22,PRPH,PTPRH,SH3TC2,RGS4,RGS7,SCG5,SYBU,BEX1,RAP1GAP2,SAMSN1,CEP68,RGL1,SYT1,TNS1,DNAJC12,TRIM9,NAV3,PLSCR4" Drug 573_UP deferoxamine mesylate salt; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.34E-03 1.00E+00 9.00E-03 1.02E-01 45 184 "AMPD3,APAF1,APBA2,PDXK,ASCL1,ASPH,ST3GAL5,CBFA2T2,SCARB1,CDH18,CHRNA4,PICK1,CNTN1,ARHGEF10,FEM1B,EFNB3,EGFR,ENO2,OLFM1,IP6K2,DPYSL4,GAP43,SOX21,ADAM22,MXI1,OGG1,SNTG1,PDE1C,PFKFB3,PFKFB4,PFKP,MAPK3,PTPRN,RGS12,RNASE1,RNASEL,TCP11L1,SH3BP2,KDM4B,KDM3A,OBSL1,TRPC1,VLDLR,PRDM2,SLC17A7" Drug 4205_UP Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.34E-03 1.00E+00 9.00E-03 1.02E-01 45 184 "APC,CDC14B,ZSCAN18,NRP2,IL33,CFAP410,MAP7,SCARB1,NEURL1,LARGE1,CHN2,CHRNB2,CNTN1,CREM,PLCH2,ERC2,CTH,FRMPD4,PITPNC1,HIPK3,PLEKHO1,TRMO,PDLIM5,DENND2A,DISC1,ALDH1L1,HTR2A,KCND3,MT1M,MX1,PDE2A,PDGFRA,SMOX,SPATA6,PTHLH,ZSCAN32,RGS4,RGS12,KCNIP1,RIMS1,TBL1X,TPM3,ZBTB38,SLC17A7,HRASLS" Drug 6184_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.36E-03 1.00E+00 9.07E-03 1.03E-01 44 179 "ADORA1,PDE8B,BTRC,MAP7,CHRNA4,COL9A2,CREM,SIPA1L1,PDE4DIP,SNPH,DGKG,SV2B,FAM13A,MBNL2,SORBS3,KIAA1109,FGFR1,BAIAP2,CAP2,CACFD1,FAM107A,ITIH2,PDE4B,PFKFB2,PLCL1,PMP22,MBOAT7,PRKACB,CEP41,KLK6,PTPRN2,MARCH1,SCN2B,HSPA4L,FRMPD1,CDK19,ATP10B,JMJD6,PSD3,OBSL1,SEZ6L,ZMYND8,ZBTB38,SLC17A7" Drug 1169_UP geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.36E-03 1.00E+00 9.07E-03 1.03E-01 44 179 "AGT,TRMT9B,APC,PPP4R4,CFLAR,LDLRAD4,TPP1,IQCK,SEC31B,CREM,CRY2,RCAN1,EFNB3,FAM13A,MBNL2,SORBS3,CDKL3,F5,OGA,ATXN2L,HSP90AA1,NUCB1,KCNK10,PDE4B,PDE4D,PLCD1,PMP22,MBOAT7,PRKACB,ZNF493,FBXW7,RPS6KA2,RXRA,HSPA4L,SLN,TSNAXIP1,MAPK8IP3,ARHGEF9,KAT6B,TPD52,TPM1,UCHL1,FLRT2,PLPPR2" Drug CID000039484 1-methyl-4-phenylpyridinium Stitch 1.36E-03 1.00E+00 9.08E-03 1.03E-01 37 144 "SLC25A14,AIFM1,CDO1,SLC22A6,SLC25A27,SLC29A4,DRD1,GFAP,LOXL3,GPR37,GRIK1,GRIN2C,GRIN2D,GRM2,GRM3,GRM8,LINGO1,PACRG,MAOB,NOS1,OGDH,ABCB1,MAPK3,MAPK8,MAPK9,MAPK10,NDUFS7,PTPRD,QDPR,SLC22A4,SNCA,MGRN1,CYB561A3,SIRT1,ZMAT3,TK2,PORCN" Drug 3464_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.37E-03 1.00E+00 9.17E-03 1.04E-01 42 169 "APAF1,APBB2,KIF1A,LHX2,ZFYVE9,MICAL2,TBC1D5,RIMS3,RHOBTB1,SACS,EGR3,EIF5,PLEKHO1,TESK2,CAMSAP1,EVL,CAMKK2,B4GALNT1,GRB10,BRINP3,MAPT,MXI1,PIK3R1,RALGDS,RGS10,ROBO1,LGR4,FAM102A,TMCC1,CDK19,CAMTA2,PLCB1,ASTN2,TBL1X,ZMAT3,TNNT1,SMUG1,ZNF32,HPS4,UBE3B,PHTF2,NETO2" Drug CID000003661 atropine sulfate Stitch 1.39E-03 1.00E+00 9.29E-03 1.06E-01 76 347 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,ARNTL,BCHE,CACNA1B,CACNA1E,CACNA2D1,HAP1,CCK,CCKBR,INA,CHRM1,CHRNA4,CHRNB2,CLCN3,CLCN4,CP,BOC,DMPK,MED12,DRD1,EDN1,EDN3,TNK2,FOXM1,B3GAT1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,INPP5K,CRCP,GLS,GUCY1A2,GUCY1B1,HRH3,HTR5A,BCO1,NOS1,NPY,NPPA,NPR2,OPRL1,PDYN,PENK,PIK3C2A,PTPRN,PTPRN2,SNCA,SPP1,SST,ABCC8,SYN1,SYN2,TAC1,TAC3,TACR1,AZIN2,TRH,VIPR2,PORCN" Drug CID000062276 lactofen Stitch 1.40E-03 1.00E+00 9.38E-03 1.07E-01 24 82 "APBA2,BTK,CACNA1I,CACNA1G,TOX,SPOCK2,WDR20,EXOG,FLT1,MEF2C,SESN3,PCDHGC3,PDPK1,PMS2,IRX1,COBL,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,TMEFF2,TUBA1A" Drug ctd:D007545 Isoproterenol CTD 1.41E-03 1.00E+00 9.45E-03 1.08E-01 198 1034 "SERPINA3,ACADM,ADCY5,ADCY6,CCDC85A,TMCC3,ADD3,ADRA1B,ADRB2,AP1B1,AGT,SORCS2,ADGRF5,ARHGAP20,MYH7B,APAF1,GPAM,PHYHD1,SHROOM2,ARNTL,ARRB1,ARRB2,ASPH,ATP2A2,N4BP2L1,CA4,HAP1,CAMK2B,CH25H,SPAG9,MAP7,CD38,CDH2,LGI1,CDO1,CRLF1,CLCN3,CLU,ABCG2,MYRIP,CP,CPS1,CREM,GDA,VCAN,ARHGAP24,SPOCK2,PITPNC1,DCT,HEPH,ARNT2,DMD,EDN1,EDNRA,EDNRB,HIPK3,TMTC1,FRY,EGFR,SORBS3,ELN,CALCRL,EPS8,DENND4A,EZH1,TUBA1B,FCGR3A,FGFR3,TMEM164,FHL1,FOXO3,FLT1,TACC2,SORBS1,RASL10A,OGA,GALNT15,GCNT2,TUBA8,SESN1,CSDC2,GGT5,PPARGC1A,LYVE1,GK,RND1,GLUL,GNAS,GNG3,STON1,RAPGEF4,PTPN5,PSIP1,IRAK3,HLF,HMGCR,AGBL5,HPCA,HSPA1L,HSP90AA1,SMAP1,IFI16,IGF1,IL12A,ITGAM,ITPKB,KCNB1,KCND2,LAMA2,ARHGAP12,PACRG,SMAD1,MBD1,MEF2C,CCDC80,ADAM22,MSR1,MDGA1,MYCN,MYH7,MYL3,MYO5A,NCF2,NOS1,NPPA,NUCB2,OGDH,PDE3B,PDE4A,GNG2,PENK,ABCB1,PIK3R1,PKM,SH3KBP1,PPARA,RASGEF1B,PRKCB,MAPK3,MAPK8,PRODH,PROX1,PTH1R,PTPRD,PTX3,PEX2,QDPR,RAD52,BSDC1,TTLL7,KLHDC8A,PCMTD2,FBXW7,CLIP1,SCN3A,SCN4B,SCN7A,SOX6,SELL,PPM1E,DOCK10,ABLIM3,SMTN,SLC8A1,MBD5,PALLD,TNIK,SPP1,KIF1B,TROVE2,NXT2,KLHL7,SYN2,TAC1,POPDC3,MCF2L,CUX2,DOCK9,HIF3A,CRB1,THRA,TIAM1,TIMP4,TLR4,R3HDM1,TPM1,ZNF346,PPIL6,TUBB2A,UBC,UCHL1,TBC1D15,KCNT2,SPHK2,ZBTB16,REEP1,INTS3,RNF103" Drug CID000060662 mibefradil Stitch 1.42E-03 1.00E+00 9.50E-03 1.08E-01 20 64 "CACNA1I,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,CACNA2D2,DBI,CACNG7,CACNG3,CACNG2,KCNN1,KCNN3,KCNK10,PKD1,RYR1,RYR3,TPCN2,SPX" Drug CID000448159 CC-I Stitch 1.42E-03 1.00E+00 9.50E-03 1.08E-01 20 64 "APAF1,CACNA2D1,CBR1,CX3CR1,DBN1,DPYSL2,GFAP,GRM1,GRM2,GRM3,GRM5,GRM8,LIMS1,NPY,OPRL1,P2RY1,PRKCG,SLC1A2,SLC6A1,TACR1" Drug CID000001869 NSC97113 Stitch 1.44E-03 1.00E+00 9.63E-03 1.10E-01 17 51 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,DPP10,GNE,CAP2,AHCYL1,GPM6A,RNASE1,PBRM1,AHCYL2,METTL3" Drug CID000023943 U nu Stitch 1.44E-03 1.00E+00 9.63E-03 1.10E-01 17 51 "TAOK1,CNOT8,COL11A2,COQ7,PSD2,MAG,MBP,MOBP,MOG,OMG,PLP1,PMP22,PSAT1,MGRN1,PSD3,WIPF1,GJC2" Drug CID000096918 atherosperminine Stitch 1.44E-03 1.00E+00 9.63E-03 1.10E-01 10 23 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000015465 AC1L25Y6 Stitch 1.44E-03 1.00E+00 9.63E-03 1.10E-01 10 23 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CACNA2D1,CALM1,CBR1,ATP2C1,PNMA2,WLS" Drug CID000002753 cilostamide Stitch 1.45E-03 1.00E+00 9.66E-03 1.10E-01 32 120 "ADCY5,ADCY6,ADCY8,ADRB2,PDE8B,ALDH7A1,CALM1,CCK,LRBA,CNTFR,SH2B1,VCAN,TUBB3,RAPGEF4,CIT,IGF1,IGFBP1,NPY,NPPA,NRDC,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PRKACB,PBRM1,FNDC3A" Drug CID000003639 hydrochlorothiazide Stitch 1.45E-03 1.00E+00 9.66E-03 1.10E-01 32 120 "ASIC1,ACLY,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,ADD2,BRAP,AGT,CA4,CA8,CA12,CACNA2D1,NGB,ASIC3,SLC22A6,DCT,ELN,HBA1,KCNK3,KCNMA1,NPPA,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,CA14,TSC1,WNK1" Drug CID003531687 SCH 50911 Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "CBS,CHRM1,CNR1,GABBR1,CNTN3,SLC6A1,ADHFE1,MLST8" Drug CID000366135 NSC-634462 Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "ALDH7A1,KHDRBS3,PDE3A,PDE3B,PMP2,SYNE1,MAP3K12,TUBA1A" Drug CID000003956 LY163892 Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "BRAP,CACNA2D1,CLTB,TBPL1,AASS,GCNT2,BCO1,WLS" Drug ctd:C008890 phosphoramidon CTD 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "AGT,EDN1,EDNRA,EDNRB,EGFR,MAPK3,SELL,TAC1" Drug CID010130754 2-PMPA Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "FOLH1,GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID000448216 pentasulfane Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1E,B3GAT1,TACR1,TRH" Drug CID000134141 fluphenazine-N-mustard Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "CALM1,KRIT1,DRD1,GAD1,GAD2,MYLK2,PENK,SST" Drug CID000003083 DM-nitrophen Stitch 1.45E-03 1.00E+00 9.67E-03 1.10E-01 8 16 "CACNA1A,CALB2,MYH6,QDPR,RYR1,RYR3,TMPO,TMEFF2" Drug 3017_DN Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "C3orf14,BCAR3,ANK2,ANK3,NCOA1,NUMB,ATP2B2,AZGP1,SYNJ1,MTMR3,CAPN3,FAM149A,BAG4,NRG2,SLITRK5,AASS,C3orf18,CAMSAP1,GABRA2,SIGLEC8,GNAS,GPD2,GRK4,KLF12,NINJ2,MAPK7,MAPK8,PLPPR1,PTK2,TCP11L1,RXRA,SEC14L1,RASA3,SH3BP2,NLGN1,ANKRD6,SNCA,FCHO1,CEP68,STX1A,KIAA1107,TCF7L2,TEX15,TRO,ZMYND8,SEMA3B,PHTF2,JPH3" Drug 7156_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "BIN1,MARK4,CFLAR,SYNJ2,TAOK2,WHRN,HAPLN1,IPCEF1,PDE4DIP,CTNND2,HDAC9,GIT2,SMG7,DRP2,YAF2,FAM13A,SORBS3,EPHA5,EFEMP1,FGF1,BAIAP2,SEMA4D,TRMO,PDLIM5,FYB1,GAB1,SEPT9,GLI2,GUCY1B1,IRAK3,INPP5B,JAK2,OPRL1,PLCD1,MBOAT7,MED1,CNNM2,PTPRE,TMEM231,RAD52,KHDRBS2,KIRREL1,ERC1,BHLHB9,R3HDM1,MICAL1,WIPF1,RNF170" Drug 3020_DN Nadolol [42200-33-9]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "C3orf14,ACTN2,NDRG2,MTUS1,BIN1,ANK3,NCOA1,ATM,NRP2,CACNB2,CACNB4,CBFA2T2,SCARB1,ABCG2,CLOCK,RUBCN,DYRK1A,E2F5,SIDT2,FAM13A,C3orf18,RASGRP2,PDLIM5,FAM49B,GABRA2,SIGLEC8,ADAM28,GNG4,GRK4,GRM7,MAP4,TAGLN3,CNOT4,PHKG1,PLEC,PROX1,TMEM231,MAP6D1,SYNDIG1,EPN2,SMTN,IZUMO4,UNC5B,PARD3,KAT6B,TRO,KCNAB1,NUP214" Drug 2935_UP Harpagoside [19210-12-9]; Up 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ADORA1,BCAS1,SEMA4G,PLA2G4C,BCL2L2,CACNB4,CLCN4,STOML1,DNAJB5,RAB26,CREM,USP6NL,SV2A,SHANK1,DTNB,EDNRA,EFNA3,SORBS3,ELAVL3,KAT8,ZNF44,GAD2,RND1,GNG4,GPR22,RAPGEF1,SOX21,AFDN,MYO9A,PDE4D,PFKFB4,PLCD1,MAPK8,LRRC49,PTPN13,RASA3,ST6GAL1,HECW1,ZC3H13,SPTAN1,CDK19,PDLIM2,THRA,TMOD1,TNS1,FAM155A,GDPD5,PRDM10" Drug 5853_DN Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ACTN1,ADD1,BRAP,SHROOM2,NCOA1,SLC4A4,ALDH7A1,C5,CA12,HIP1R,LARGE1,CNOT8,KIAA1549L,CNTNAP2,SPATA2,KLHL3,SUGP2,IRAK4,ING4,STX2,SPEG,TRAF3IP2,DISC1,INPP5K,ZNF276,GNG4,RASSF8,ARHGAP19,PDE4D,PIK3CD,ELOVL2,PTN,ZSCAN32,RAB3IL1,GTDC1,SH3GL3,ST6GAL1,POGZ,KAZN,IQCE,PSD3,TGFBR3,CBX5,HIRA,PLPPR2,XRCC4,SMIM8,PHTF2" Drug 318_DN LY294002; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABHD6,APBB1,CD86,CD38,LHX2,ARHGEF6,PICK1,C2CD2,ARHGEF10,SIPA1L1,DGKG,DBN1,RCAN1,RBM12,EFNB3,COQ7,FGFR3,GLS,GNAO1,GRK4,GRIK1,GRIN1,GRM2,SLC2A6,SYNPO,ITPKB,NTRK3,RETREG1,FSD1,TMEM104,MTMR10,RAB3A,RXRG,SGK1,SH3BP2,SLC6A9,KBTBD4,SPART,ELOVL4,KAZN,EXOC7,WWC1,TMEM151B,TEK,NPL,REEP1,PRDM10,MVB12B" Drug 4525_DN Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "BRAP,APC,CDC14B,ALDH4A1,SYNJ2,SCAPER,MAP7,RCBTB2,RAB28,CLCN4,AKAP7,HAPLN1,DBN1,DBT,EXOG,EDNRA,FCF1,EFNA3,ERCC2,PRELID3A,SYT17,USP19,GPD2,RASSF8,SCIN,MAPT,NDP,CNOT4,PPP5C,ELOVL2,PEX5,RAB3A,PID1,FBXW7,TRAPPC13,AMBRA1,DZIP1,FAM214B,WDTC1,SS18,ASTN2,ZMAT3,UGT8,WIPF1,XRCC4,NT5M,HPS4,NAV3" Drug 5687_DN Epiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "APBB2,APLP1,ATP6V0A1,CA4,ZFYVE9,VAX2,ARMC8,SMARCAL1,BAG4,ABCG1,PDE4DIP,DZIP3,CTNND2,ARMCX2,MFAP3L,RABGAP1L,MED12,DRD1,OPTN,PRELID3A,CGREF1,TRAF3IP2,SRCAP,GPR19,CNTRL,IPO5,MID1,MITF,MPP2,ADAM22,ZNF862,NDUFA5,NUMA1,SLC25A23,PPP3CC,MAPK8,PTHLH,ZSCAN32,RIPOR1,RALGDS,RAP1GAP,NEK11,SHANK2,SPART,MAPK8IP3,KIAA0930,TGFBR3,VGF" Drug 2648_UP Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ADORA1,AP2A2,TRMT9B,AMPD3,FAM131A,CDC14B,SLC2A11,ADGRB1,CACNB2,CAMK2B,ARHGAP33,CHN2,SLIT2,TPP1,LRIG1,DTNB,PIPOX,ANKMY1,DLC1,FGFR1,SEMA4D,PRELID3A,GPR153,C1QL1,IL6ST,MAN2A2,MBD1,MIA2,NDUFA5,NOS1,MBOAT7,PACSIN1,RGS10,TCP11L1,DOCK10,KIF13A,ZCCHC24,IZUMO4,SPTAN1,IQSEC2,SYT11,PLCB1,EXOC7,RALYL,PARD3,ZKSCAN5,FAM13C,AP3B2" Drug 6002_UP Iobenguane sulfate; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABHD6,FZD9,MRTFA,SEMA4G,SGCE,THSD7A,USP2,MTMR7,CDH10,CHM,CABP1,SMARCAL1,PDE4DIP,ABCC9,EDNRA,EFNA3,C3orf18,EFCAB2,OGA,HBS1L,GATM,GRK4,GRIK5,GRM8,IGSF1,KCNB1,KCND3,KCNH2,KCNN1,MOBP,KCNK10,PFKFB2,PPP5C,ZSCAN2,RAB3IL1,MYH14,SBF1,ASAP3,SMARCD3,TSNAXIP1,KIAA0930,DOCK9,TGFBR3,THRA,HEY2,WIPF1,MKRN3,SCG2" Drug 3418_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "AP2A2,PLA2G6,C1QTNF3,DOC2A,AMPD3,CDC42BPA,GAS7,CDK10,SEMA4G,ARRB1,CDK13,RASL11B,SCAPER,BTRC,CFAP410,CALB1,SCARB1,CACNA2D2,SOCS6,TPP1,ENTPD4,PLCH2,DCAF8,MED24,DTNA,OPTN,ELAVL3,SPEG,ACSL4,KAT8,FGFR1,CAMKK2,RND1,GLYR1,KCNJ5,KIFC3,KITLG,RGS10,PSD3,AHCYL2,CHST8,ZNF34,TK2,TMOD1,METTL3,ZKSCAN5,ITM2C,MPPE1" Drug 383_UP cobalt(II) chloride hexahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABR,DGKD,ARNTL,NCOA1,CADM3,ATP6V0A1,BMP7,BTRC,KRIT1,CD86,FOXN3,CHRM4,CHRNB2,SLC4A7,OSBPL3,EFNB3,SUGP2,FABP7,ZNF589,TRMO,PDLIM5,TMEM8B,SRCAP,RND1,GLRB,GLS,LILRA2,BTN2A1,HMX1,IL12A,ITGAM,L1CAM,MAPT,ODF2,SNX10,MAPK8,SCNN1D,SH3BP2,SLC1A3,KDM4B,UHRF1BP1L,TSPYL2,SEPT8,COBL,POPDC3,SLC13A3,SLC17A7,MPPE1" Drug 6049_DN (cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "RALGAPA1,ASIC1,AP2A2,LTBP4,FAM131A,ARHGDIG,CACNA1I,USP2,SEPT7,CDH10,CRLF1,CSF1,ARMCX2,RCAN1,EFNA3,RBM12,EN2,DMTN,FOXG1,C1orf61,GPR153,GABRA2,SRCAP,GRM1,INPP5B,KCNH2,LIG4,MAP2,CNOT4,NRGN,NUMA1,WDR25,RGS10,TCP11L1,WLS,SBF1,ZNF821,ANKRD6,MAPK8IP3,ELOVL4,PLCB1,SEMA4A,ZEB1,DICER1,CHST8,SLC44A1,TRPC1,KCNAB1" Drug 6356_DN Pinacidil [85371-64-8]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ACLY,PPFIA3,CASK,CFLAR,CDK5R1,MTMR2,SPAG9,CDH2,CLCN4,QKI,CHD1L,ARHGEF4,ZNF337,MATR3,GIT2,ARMCX2,DNAJC6,FCF1,USPL1,FER,ZMYND11,TMEM8B,EML4,KIF2A,MAPK9,RIPOR1,RAB3IL1,UEVLD,CLIP1,SUPT20H,AMBRA1,SMARCC2,TTC17,TMCC1,TNIK,KDM4C,TEX2,ARHGEF9,ANKRD12,TCF4,RBFOX2,METTL3,DNAJC12,WNT7A,NDRG4,ZFAND5,ACTR3B,ADAMTSL3" Drug 3403_UP Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "BIN1,APC,MARK4,ALDH4A1,ATP1A2,CACNA1I,CACNB2,TAOK2,TPP1,CSF1,RASSF2,RCAN1,EFNB3,MBNL2,ELN,EML1,EXTL1,ACSL4,FGFR3,SRCAP,GFER,GLS,POLL,TDRKH,STON1,INPP1,KCNJ5,MDM4,MIA2,KITLG,AFDN,SERPINI1,SLC25A23,NKAIN1,RAB3A,SHANK2,CLSTN2,INKA2,PLCB1,CRTC1,PCDHA5,THRA,TK2,TMOD1,TPD52,PRDM2,KCNAB1,ST7" Drug 1079_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "APP,ATM,CFLAR,BMP7,MTMR3,MTMR2,C5,HIP1R,UBE2L6,SRSF11,LHX2,C2CD2,FEZ1,SOCS5,PDE4DIP,RIMS3,GIT2,DBT,DNAJC6,MFAP3L,FBXL5,RCAN1,ENO2,ERBB2,TESK2,BAIAP2,PDLIM5,HTATSF1,RAB40B,PADI2,MAP4,NUCB1,PLEC,SYTL2,ZSCAN32,ANKRD6,NUBPL,SHANK2,SLC15A2,ELMO2,PDZRN3,ZSWIM8,DIP2A,JMJD6,TCF7,NSD1,PARD3,RPRM" Drug 5996_DN Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "SLC12A5,AK2,MRTFA,APBB2,APLP1,ASPH,MTMR3,ARHGEF2,HOMER3,ARMC8,ENTPD4,CSF1R,CNTNAP2,ZFYVE16,SGSM2,RABGAP1L,DRD1,SORBS3,ANKMY1,KAT8,ZNF589,FAM49B,USP19,IL6R,MAP4,NFYA,NPR2,CCSER2,PRKAR1B,SAMD9,PTPRG,GTDC1,RGS10,TRAPPC13,FOXRED2,SGK1,AMBRA1,FAM214B,SPTAN1,LHPP,PLCB1,DNMBP,TK2,ZKSCAN5,VAV2,TFIP11,MAP3K12,GDPD5" Drug 3442_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ALCAM,ATP6V0A1,MPDZ,BCL7A,CFLAR,GYG2,CRLF1,ZFYVE9,DNAJC6,RABGAP1L,EFNB3,SORBS3,STX2,CDKL3,RRAGB,ZNF589,FGFR1,CSPG5,USP19,MSL3,PCSK1N,IGSF1,MATK,TM6SF1,MPP2,GIT1,ADAM22,NEK1,NPTX1,SETD4,PDE3B,MBOAT7,PRKAR1B,ZSCAN2,RGS10,FERMT1,MAPKBP1,CAMTA2,VPS13A,TNS2,AP4E1,PARD3,CDK20,ZNF74,REEP1,SEMA3B,PCBP4,KAT6A" Drug 2190_UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABAT,BIN1,APC,PDE8B,ALDH4A1,N4BP2L1,BCL2L2,CFAP410,DAPK3,SPOCK2,CTIF,SMG7,DMPK,DSCAM,CELSR3,MBNL2,ERBB2,ETV1,FER,KIAA1109,FOXG1,C1orf61,DCTN2,ADAM28,STON1,MUM1,JAK2,KCNJ5,MDFI,DUSP26,CCSER2,SLC25A23,POU6F1,PPP2R2B,PTPN13,FAM120C,PPM1E,CPEB3,WDTC1,ZCCHC24,SPTB,SPART,TROVE2,IQCE,TCF4,ATP13A2,HIRA,UGT8" Drug 3238_DN Ambroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ADORA2A,LTBP4,APBA2,ARHGDIG,KIF1A,SCAPER,BAIAP3,SRSF11,QKI,WHRN,ENTPD4,CRY2,CSF1R,FAM169A,EIF4G2,HSD17B14,LRRC23,VPS26C,PDLIM5,GABRA2,DHX35,KCNQ3,MDM4,MGAT3,KITLG,MSR1,NDUFA5,NEK1,PTPA,PPP3CC,MAPK8,RELN,C1orf54,RGS10,RGS12,ROBO1,PKNOX2,SMARCD3,WDTC1,SPART,PIK3R5,CDK20,ZMYND8,VGF,TFIP11,KCNAB1,TIGD6,SSPN" Drug 1_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABR,ADORA2A,AP1B1,BIN1,ANK2,PPFIA3,SYNJ2,ARHGEF7,CHGB,CHN2,VAX2,TMEM184B,ARHGEF6,ECE2,ARHGAP32,DCAF8,INTS1,DMPK,DTNA,DUSP9,FEM1B,SIDT2,EFNB3,SUGP2,PRKAG2,TRMO,RUNDC3A,CNTRL,ATXN2L,KLF12,ADAM22,NTRK3,PBX1,CEP41,PRPSAP2,VPS13C,ATXN2,SEC14L1,SH3BP2,SCN3B,NMNAT2,TRPC1,SSBP2,TUB,PLPPR2,WRN,PRDM2,CAMK1G" Drug 481_UP WY-14643; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ABHD6,BRAP,APBB1,PDXK,CADM3,SYNJ2,CAMK2A,CACNA2D2,C2CD2,SDC3,ARHGAP32,SORBS3,COQ7,FABP7,OLFM1,HPCAL4,FYB1,GAD2,ALDH1L1,CYP46A1,GRM1,RASSF8,MAN1B1,ATXN2L,SYNPO,HTR2A,MAPT,MBD1,MMP17,MYL3,NTRK3,SETD4,LRRN3,MTMR10,C1orf54,TCP11L1,DOCK10,SLA,SLC1A2,SLC9A5,KBTBD4,SPART,POGZ,TCF7L2,TPM3,TRPC1,TMPRSS5,RPRM" Drug 3560_UP Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "AP2A2,PLA2G6,APAF1,BCAS1,PPP4R4,ATM,SLC2A11,SYNJ2,SCAPER,BAIAP3,HIP1R,CDH2,CLGN,CNN3,CPS1,ARHGEF10,SMG7,EXOG,LRRC23,KHDRBS3,TRAF3IP2,GAD1,SRCAP,IL6ST,ITPKA,KCNJ4,KCNK1,SMAD1,MDFI,NF1,PC,PENK,PFKFB2,PLEC,SEMA6D,FAM214B,COA1,SMARCD3,SPTAN1,ACSBG1,ROBO3,AHCYL2,SLC44A1,VIPR2,WIPF1,SLC30A3,WNK1,ZNF248" Drug 1829_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ANK3,NUMB,CARS,AP4M1,ZMYM4,FOXN3,CLU,ARHGEF6,IQCK,SLC4A7,CDC42BPB,CTH,PPP6R2,SGSM2,SUGP2,VPS13B,FHL1,POMT1,ATP2C1,NCKAP1,SEPT9,GLUL,NR3C1,MARK3,PDCD2,PPP3CC,PRKAB2,PRKACB,BCAS3,TMEM104,ROGDI,EPN2,RAB3GAP1,KBTBD4,SMARCC2,TMCC1,GLT8D1,UHRF1BP1L,SUPT5H,WSCD1,PARD3,TPD52,TSC1,HIRA,PLPPR2,TFIP11,UPF3A,ST7" Drug 5012_DN Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "AK2,BIN1,APBA2,FAM131A,ARRB1,CADM3,ST3GAL5,MAGI1,FOXN3,LHX2,ZFYVE9,STOML1,AKAP7,RIMS2,SEC14L5,C2CD2L,SGSM2,DNM1,EFNA3,EN2,ZNF589,BAIAP2,FHL1,PDLIM5,CGREF1,USP19,RASSF8,IL6R,MSI1,ZNF862,PRPH,WDR25,FAM120C,RAB3A,CEP97,GTDC1,RGS12,PPP1R9A,CPEB3,BTBD7,LIMCH1,ZHX3,CLSTN2,POPDC3,TCF7,PSD3,CRTC1,MPPE1" Drug 5355_DN Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ASPHD1,PPFIA3,BCL7A,KRIT1,LRRFIP1,FOXN3,LHX2,QKI,NIPBL,COL4A5,AKAP12,ARHGEF10,USP6NL,DCAF8,LYPD1,MED12,SH3GLB1,EPB41L2,TESK2,KIAA1109,GAA,NCKAP1,ARFIP1,GHR,GPR37,BTN2A1,MUM1,BRINP3,MAP4,MEIS2,SETD4,PCMT1,SSH1,PMP22,PCMTD2,SFPQ,SLC15A2,SPART,SS18,VAMP1,TACC1,IQCE,TRIO,LMF1,PCBP4,WIPF2,EPM2A,MARCH8" Drug 7167_DN Natamycin [7681-93-8]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "ADD3,BCAR3,CDC14B,ARHGAP5,NUMB,EIF4G3,CFLAR,SYNJ1,OSGIN2,PTBP2,CREM,CSNK1E,DCAF8,FBXL5,RABGAP1L,DLG3,NR1D2,RCAN1,DTNA,FEM1B,EPB41L1,RACK1,FYN,GPR37,MAP4K5,RBPJ,KIF5C,SLC11A2,MED1,ARID4A,SUPT20H,ITSN1,PEX26,SLC15A2,ELMO2,SMARCC2,CDK5RAP2,ZSWIM8,UHRF1BP1L,SS18,FCHO1,TACC1,ARHGEF12,RPRM,UPF3A,MFF,EVI5,PHTF2" Drug 418_UP haloperidol; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "AGT,APOC1,PPFIA3,N4BP2L1,SYNJ2,CACNA1A,CANX,CBFA2T2,CDH18,TPP1,CSF1,CSF1R,DRP2,DTNB,FEM1B,EFNB3,EPHB1,NRN1,FOLR2,NSG1,GLRB,LUZP2,FAM107A,ATXN2L,MMP17,NRGN,GPR173,CCSER2,FXYD1,CEP41,MASP1,FAM184A,ENOX1,CRTAC1,ATXN2,ZNF821,FNDC3A,KBTBD4,ELMO2,AJAP1,ADGRL3,ZNF34,TNS1,PDIA2,WNT7A,ZBTB16,UPF3A,SLC17A7" Drug 2167_UP Benzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "LGR5,DNAH17,CADM3,ADGRB1,FUBP1,BTRC,REPS2,CNTFR,CREM,CRYM,AATK,VCAN,GSDME,HIPK3,ELAVL3,BSCL2,C3orf18,LRRC23,CEND1,FGFR1,FHL1,PDLIM5,GPR19,KIF3A,WIF1,MAP4,ZNF862,NNAT,PGAM2,PLCD1,PPP5C,LRRC49,PTPRN2,RIPOR1,NEK11,TCP11L1,FOXRED2,SBF1,GALNT10,ANKRD6,SMARCD3,KDM4B,ATP10B,SS18,TACR1,CDK20,WIPF1,ZFP37" Drug 3078_DN Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "KIDINS220,AP2A2,C1QTNF3,APAF1,APC,MARK4,RIPK1,CAPN3,CBR1,SLC16A4,SCARB1,SOCS6,TPP1,CLOCK,DTNA,FAM13A,SEC24B,EVL,FYB1,TRAF3IP2,HBS1L,ERAP1,DISC1,INPP5K,LILRA2,PCLO,LAMA2,NUCB1,SETD4,STRN3,MINDY2,PPP3CC,MAPK8,SIDT1,TCP11L1,PPM1E,KDM4B,EMC1,SPTAN1,SZT2,SYNE1,SIK3,KAT6B,TPM3,NPDC1,TFIP11,KCNAB1,UBE3B" Drug 4094_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "NR0B1,LTBP4,MRTFA,GAS7,APP,BRINP2,MTMR3,CAMK2B,CLCN4,HAPLN1,MICAL2,SPOCK3,SGSM2,DSCAM,RCAN1,TNK2,SRPK3,KIAA1109,OLFM1,NSG1,RUNDC3A,GPD2,RAPGEF4,GRIA4,SPACA9,GSTM5,ELOVL5,IRF8,KCND3,KCNN1,MDM4,MMP16,MOBP,DDX25,NUCB1,PHKG1,PMP2,RAB3IL1,KCTD17,SCNN1D,SH3BP2,SLC11A1,SOX2,CDK19,OBSL1,CRTC1,SPX,NSD2" Drug 1969_UP Dibucaine [85-79-0]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 1.46E-03 1.00E+00 9.68E-03 1.10E-01 48 200 "APAF1,ARNTL,CFLAR,MTMR2,GYG2,BTRC,SLIT2,ZFYVE9,CLCN4,SLC4A7,NCOR1,CSF1R,ARHGAP32,TM9SF4,TBC1D5,ZNF804A,DTNA,TRMO,FYB1,ZNF44,TXNL4A,HNMT,IFI16,KCNN1,KIF2A,NCF2,NTRK3,OXTR,ENPP2,RETREG1,PTPA,TMEM104,BSDC1,RLBP1,CLIP1,SAFB,CHD9,ARHGEF40,IFT122,WDTC1,ZC4H2,FCHO1,TTBK2,TCF4,TST,ZKSCAN5,NPDC1,RNF103" Drug 1521_DN Cyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ARID1A,GAS7,FAM131A,CFLAR,BTRC,MAP7,CBFA2T2,FOXN3,SLIT2,CLCN3,SDC3,GIT2,FBXL5,TMCC2,CNNM1,SIDT2,SORBS3,EPB41L1,SYT17,INPP5K,COPS8,GLYR1,RAB30,GLS,GNG4,MAP4K5,PADI2,DHX35,IGSF1,MPP2,GIT1,SLC11A2,SETD4,RETREG1,RAB3A,ATG16L1,TRAPPC13,SBF1,ZNF821,PPP4R3A,BTBD7,POGZ,IQCE,TNS2,TMEM121,PARD3,GDPD5" Drug 3135_DN Alfaxalone [23930-19-0]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ABHD6,PLA2G6,APAF1,MARK4,ZBTB10,ATP2A2,MAP7,CCNT1,SCARB1,TPP1,NIPBL,SIPA1L1,ZNF337,DGKG,CTIF,SMG7,EXOG,DTNA,EIF4G2,SCML2,INPP5K,GLYR1,GLS,IL6ST,MBNL1,AFF1,AFDN,ZNF862,CNOT4,ODF2,P2RY1,PDE4A,RAB3IL1,ZNF493,RASA3,SLC15A2,TMCC1,ZCCHC24,SPTAN1,ATP11A,KAZN,KCTD2,CABIN1,EVI5,KCNAB1,WIPF2,PHTF2" Drug 5297_DN Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ADD1,APC,ARRB2,ADAM15,CFLAR,PLAA,CREM,CSNK1E,ZNF337,C2CD2L,RABGAP1L,TRAPPC9,SIDT2,CELSR3,EIF5,PLEKHO1,CDKL3,TRMO,CSPG5,INPP5K,TXNL4A,MUM1,TJAP1,INPP5B,ZNF862,NEK1,NPR2,PDE3B,PDE4A,RETREG1,PRPH,RAD51D,ATG16L1,RGS10,CCDC25,MAPK12,IL17RB,EMC1,TSPYL2,CADM1,VGF,VIPR2,ZIC1,REEP1,MAP3K12,EPM2A,SMIM8" Drug 6692_UP Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "SPARCL1,APBB1,ATP1A3,NRP2,MTMR3,ARHGEF2,CLCN4,CSF1,RGS6,MICAL2,RIMS2,ATN1,DTNA,PLXNC1,MRNIP,EPB41,FAM198B,ZNF44,SIGLEC8,LYVE1,SPACA9,GRM8,ATXN2L,ITPKA,KCNC1,KCNJ5,ADAM22,MX1,MYH7,SLCO1C1,MAPK8,ZSCAN32,RGS4,SCNN1D,SLC6A9,SLC11A1,CXXC4,SNAP25,SOX10,INKA2,VAMP1,ARC,CNTN2,TUBB1,DNALI1,SCG2,NLRP3" Drug 7406_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ASPHD1,ARID1A,ADRA1D,AP2A2,ALK,CDK10,ADAM23,ARHGEF6,SIPA1L1,VCAN,HDAC4,C2CD2L,EFNB3,EGFR,FGFR1,ALDH1L1,GNG3,TJAP1,ITGAM,KCNB1,KIF2A,PALM,PCDHGC3,PCDH9,MBOAT7,PTN,RIPOR1,RAB3A,RAB3IL1,RGS12,MRAS,LIMS2,FAM214B,PKNOX2,SLC6A9,SNCA,SOX2,CDK19,TAC3,ANKRD12,PCDHA5,AHCYL2,TPD52,ZBTB14,HPS4,MVB12B,UBE3B" Drug 3871_DN Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "PLA2G6,MRTFA,APBB2,GAS7,CRLF1,WHRN,NCOR2,USP6NL,RIMS3,CTIF,ATN1,HSD17B14,DMTN,KAT8,ZNF589,FAM49B,GCNT2,RAB30,GPER1,ATXN2L,MAP2,MMP17,BCO1,CNOT4,NPR2,RETREG1,PLCD1,PPP5C,PRKCB,FAM120C,PEX5,RAB3A,RAD51D,RGS12,BTBD7,SLC22A4,SMARCD3,LIMCH1,ZBTB43,MAPK8IP3,ARHGEF9,SMG6,KIAA0930,TNS2,THRA,EVI5,ITM2C" Drug 5049_DN Indomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ARID1A,NME5,ANK3,APP,CHN2,TPP1,AKAP7,CSF1R,DBT,HP1BP3,PARD6A,EFNA3,MBNL2,ING4,PLEKHO1,SPEG,KIAA1109,FOXG1,B4GALNT1,GPR37,CNTRL,GUCY1B1,MEF2C,CNOT4,FA2H,SYTL2,GON4L,ELOVL2,ZSCAN32,SUGCT,ATXN7,SCN8A,SH3BP2,DZIP1,BTBD7,PDZD2,POGZ,SS18,FBXW11,SYNE1,ARHGEF12,GPR161,BEX4,CADM1,LMF1,SPHK2,EVI5" Drug 2804_UP Boldine [476-70-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ACTN2,ADRA1D,SPARCL1,MRTFA,BEGAIN,BIN1,APAF1,PPFIA3,RASL11B,ATP2B2,CACNA1I,CAMK2B,OSBPL3,CTIF,PLPPR4,MBNL2,SORBS3,STX2,CAMSAP1,FHL1,AFF2,OGA,GFER,HPGDS,MSL3,GRIK2,GRM7,HAS2,KCNN1,KCNQ3,ADAM11,NCAM1,NF1,PCSK2,TNPO2,PKN2,SAMD9,RAB3IL1,ZNF671,ASIC4,RPH3A,BTBD7,MYH15,RIMS1,POPDC3,TRO,PRDM2" Drug 3194_DN Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "SEMA6A,LTBP4,DNAH17,ATM,ATP2A2,SCAPER,VAX2,CRY2,PDE4DIP,GREB1,ARHGEF4,KIAA0586,CTIF,SGSM2,EDNRA,ELAVL3,VPS13B,FGFR1,PRKAG2,SEMA4D,POMT1,MALT1,MSL3,POLL,LPAR4,MIA2,MSI1,NNAT,CAMKV,MBOAT7,WDR25,RAB5B,FBXW7,SMTN,KIF13A,TMCC1,ZHX3,EMC1,STX1A,ATP11A,TNS2,VGF,VIPR2,REEP1,WNK1,EPM2A,RNF170" Drug 7381_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "APBB2,APP,MARK4,ATP2A2,SYNJ2,ARHGEF2,CLCN3,HOMER3,IQCK,SLC4A7,RCHY1,NCOR1,PPP6R2,SIRPA,DNAJC6,ING4,TNK2,EN2,EPB41L1,STX2,VPS26C,ST3GAL6,ZNF589,TRMO,FYN,TMEM8B,INPP5K,EML4,DIPK1A,KHK,SCAMP5,SERPINI1,STRN3,POLG,FSD1,SCN8A,SH3GL2,AMBRA1,SLC1A3,SLC6A8,SHANK2,FNBP1,CDK19,DIP2A,EXOC7,DNMBP,ZBTB14" Drug 6098_DN Streptozotocin [18883-66-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ALCAM,MRTFA,SCAPER,GYG2,CFAP410,KYAT1,SRSF11,ARHGEF4,RIMS2,GIT2,MFAP3L,DUSP9,EFNA3,EGR3,SORBS3,ING4,ZNF589,FGF12,FGFR1,FHL1,FOXG1,IQCG,ALDH1L1,USP19,GRM8,ITIH2,KPNA5,MIA2,NUMA1,LRP12,MAPK7,ZSCAN32,CEP97,ZDHHC14,SEC61A2,ITSN1,BCAN,RBM34,KDM4B,IQSEC2,MAPK8IP3,PHLDB1,VPS13A,TRIM2,ARHGEF12,PCDHA5,SSPN" Drug 4706_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "MRTFA,BIN1,AMT,MARK4,ALDH7A1,NMT2,WHRN,LRIG1,NOS1AP,DBN1,RABGAP1L,IRAK4,ERCC2,SCML2,ST3GAL6,FGFR1,DPYSL4,FYB1,GFER,GLS,CNTRL,GRM8,MAP4,MGAT3,ADAM22,ZNF862,NF1,RETREG1,PPARA,PPP2R2B,GRAMD1C,SAMD9,RAB3A,RNASEL,FBXW7,SUPT20H,FAM214B,KIF13A,ZHX3,MAPK8IP3,IQCE,TK2,RBFOX2,XRCC4,SYNC,MAP3K12,KCNAB1" Drug 900_UP 5186324; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "MRTFA,APAF1,APBB2,ARHGAP5,ARHGDIG,C5,CACNA2D2,FADS2,HOMER3,TENM4,GREB1,CTNND2,DBT,SUGP2,EIF4G2,EN2,DENND4A,CDKL3,PDLIM5,OGA,FYB1,GNG4,CNTRL,GRM8,RNFT2,HNMT,MITF,PPP5C,PRKAR1B,GTDC1,ZNF365,PPP4R3A,SMTN,ZNF430,SLC20A2,SLC22A4,NCDN,MTCL1,EXOC7,PCDHA6,THRA,TRIO,RUNDC3B,ZMYND8,ZNF24,WNK1,FIP1L1" Drug 7018_DN Glafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ASPHD1,ARID1A,CDC42BPA,PPFIA3,APP,NUMB,ATM,ADAM15,CFLAR,SPAG9,LHX2,RAB28,CREM,CSNK1E,PPP6R2,DLG3,EIF5,MRNIP,ATP2C1,GART,COPS8,DHX35,NAP1L1,NUCB1,OPA1,POLG,PPP3CC,ZCWPW1,TRAPPC13,ATXN7,SGK1,ITSN1,AMBRA1,SYBU,TTC17,UHRF1BP1L,CDK19,CEP68,SATB2,TMPO,RBFOX2,TRPC1,NSD2,KLC2,ZNF45,URM1,ZNF248" Drug 3054_UP Monobenzone [103-16-2]; Up 200; 20uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ABHD6,SEMA4G,RGS20,ASTN1,MPDZ,RGS11,BMP7,MYRF,CHGA,NRXN2,STOML1,PCYT1B,COL9A3,ZNF337,INTS1,DCC,DSCAM,SGK2,HEYL,SRPK3,FGFR1,FGFR3,SIGLEC8,ZNF276,GLRB,GPM6B,KLF12,SCIN,IL6ST,KCNB1,AFDN,MOBP,CD200,PDZRN4,CRTAC1,ASIC4,SLC14A1,SLCO1A2,SOX15,WSCD1,DOCK9,AP4E1,RUNDC3B,VAV2,VSNL1,PMEPA1,SLC17A7" Drug 3712_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "LTBP4,BEGAIN,AMPH,APP,PPP4R4,ARSE,DNAH17,RASL11B,CACNA1D,CACNG1,KALRN,CBS,ARHGEF2,SULT4A1,AKAP12,CSF1,CNTNAP2,MFAP3L,SV2B,RABGAP1L,DYRK1A,KAT8,OLFM1,AFF2,GAD2,CPLX2,GLUL,AP4S1,ATXN2L,ITPKA,MATN3,CD200,NNAT,NOVA2,NPTX1,SYNDIG1,ABLIM3,SOX10,ZHX3,ATP11A,KAZN,PCDHGA10,HEY1,TRO,LAT2,SEMA3B,NAV2" Drug 5424_DN Cefoperazone dihydrate; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "APLP1,PPFIA3,ALDH4A1,ATM,ATP6V0A1,CFLAR,CFAP410,ARHGEF2,ADGRG1,FOXN3,B4GALT6,SLIT2,IQCK,NECTIN3,CRY2,CSNK1E,SIPA1L1,DBN1,JAKMIP2,SMG7,SIDT2,SORBS3,BAIAP2,FAM49B,HNMT,IL6ST,VWA5A,MIA2,GIT1,NF1,PLXNB1,TMEM231,ATG16L1,SBF1,BTBD7,ZSWIM8,ZBTB43,SS18,TTBK2,VAMP1,RPGRIP1L,TK2,PARD3,HIRA,KCNK12,NDRG4,GDPD5" Drug 898_DN 5213008; Down 200; 18uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ACTN1,APLP1,SYNJ2,MTMR3,CBR1,CLTB,CSNK1E,SOCS5,HDAC4,DNAJC6,DYRK1A,SEZ6L2,EGR3,CDKL3,FGFR1,PDLIM5,GPR153,INPP5K,BTN2A1,HSD17B1,JAK2,MEIS1,SLC11A2,PALM,PMP22,PRKAR1B,RIPOR1,ZCWPW1,RGS10,TCP11L1,RPS6KA2,MAP6D1,ZFP30,EPN2,TROVE2,CEP68,SEMA4A,TCF7L2,TRIM2,TNS2,THRA,TIAM1,CABIN1,TPM1,WBP2,GDPD5,TIGD6" Drug 5325_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "BRAP,APC,PDE8B,CFLAR,CACNA1D,AP4M1,PDE4DIP,DSCAM,DTNA,EGFR,EIF4G2,CDKL3,DLC1,FGF12,GAD1,DISC1,GRIK5,HNMT,DHX35,HSF2,KCNJ3,LSS,MDM4,MPP2,ZNF862,NEK1,NF1,NFYA,NTRK2,SSH1,SAMD9,PTHLH,ELOVL2,SEC14L1,ITSN1,FNDC3A,BTBD7,ZCCHC24,EMC1,ARHGAP26,PLCB1,SLC44A1,TMOD1,XRCC4,ZNF24,TFIP11,MPPE1" Drug 1927_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; PC3; HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "MAP4K3,APLP1,SHTN1,NUMB,EIF4G3,ATP2B1,KRIT1,SOCS6,FADS2,SLC4A7,NCOR1,FAM169A,CTH,GIT2,RUSC2,ACSL4,FCGRT,SEC23B,STAG2,CRCP,GLS,PRRC2B,KTN1,MEIS2,MID1,NAP1L1,SNX10,PLCD1,PPM1B,LGR4,CLIP1,AMBRA1,CHD9,SLC1A3,SLN,SMARCC2,PEG10,NXT2,PHLDB1,FAM168A,POPDC3,AGTPBP1,TCF7L2,CRTC1,PLPPR2,CLIP2,CERS6" Drug 4155_DN Ticlopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ASIC1,ADORA1,AP2A2,NME5,APBB2,APOC1,CAPRIN2,CFAP410,CA4,CAMK2G,SLIT2,CRY2,PPP6R2,MED24,TMCC2,HIPK3,EFNB3,SUGP2,PLXNC1,ING4,VPS13B,ZNF589,TRAF3IP2,GAD2,SEPT9,GCNT2,GPER1,KCNH2,KCNMA1,KIT,MMP16,NF1,PLCD1,MINDY2,PRKAR1B,RGS12,DCUN1D2,TCP11L1,SH3BP2,KIF13A,DOK5,CRTC1,TRPM2,VIPR2,MICAL1,KCNAB1,PLSCR4" Drug 6052_DN Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "C1QTNF3,LTBP4,APBB2,EPB41L5,CFLAR,CACNA1I,BTRC,CAST,SYNGR3,STOML1,QKI,CREM,ENTPD4,AKAP12,CTH,GREB1,DTNA,KAT8,C1orf61,TXNL4A,HNMT,INPP5B,KCNJ3,LMO2,CNOT4,NUMA1,PPP2R5C,RGS10,FBXW7,SBF1,SEC14L1,FBXO11,ANKRD6,KDM4C,RAP1GAP2,MAPK8IP3,ELOVL4,PHLDB1,NSFL1C,VAMP1,TCF7L2,TRIM2,PSD3,ZMYND8,ZKSCAN5,HPS4,ST7" Drug 3583_DN Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ALAD,MRTFA,GAS7,BCAS1,PPFIA3,ARRB1,CFLAR,GYG2,RAB29,CACNB2,SCARB1,SOCS6,PLAA,VAX2,CREM,ENTPD4,MICAL2,GIT2,JAKMIP2,C2CD2L,PARD6A,ATN1,CELSR3,ENO2,COQ7,CAMSAP1,EFCAB2,DPYSL4,TPK1,PRELID3A,TDRKH,KITLG,MID1,MPP2,ADAM22,NUMA1,SERPINE2,PPP3CC,RAB3IL1,EMID1,ANKRD6,ZCCHC24,ST5,EXOC7,DICER1,CABIN1,VAV1" Drug 1330_DN Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "GRAMD1B,ADORA3,C1QTNF3,CDC42BPA,APAF1,APBB2,CFLAR,MTMR2,LDLRAD4,CACNA1A,CAPN3,KYAT1,TPP1,MICAL2,RUBCN,DTNA,FEM1B,SUGP2,EIF1,GPHN,ARFIP1,AHDC1,LILRA2,MAP4K5,HSF2,TJAP1,IL6R,MIA2,SLC11A2,PDE4B,CCSER2,TMEM231,RGS10,ZNF671,FAM102A,NXT2,CEP68,NSFL1C,ATP11A,TNNT1,TPM1,SSBP2,ZNF142,FTSJ1,EMSY,NT5M,MPPE1" Drug 2064_UP Spironolactone [52-01-7]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "APP,ALDH4A1,BCL2L2,SCAPER,BTRC,CA12,SOCS6,CLCN4,DNAJB5,SLC4A7,CREM,DAPK3,SPATA2,ZNF804A,SMG7,EFNA3,FAM13A,MRNIP,TUBD1,CDKL3,SYT17,SRCAP,RNFT2,PDE4B,PFKFB2,ZFP30,PEX26,SLC6A8,SMARCD3,TNIK,EMC1,UHRF1BP1L,PEG10,COLGALT2,THSD1,CEP68,TCF4,KIAA0930,ARHGEF12,ZNF34,TIAM1,TK2,KAT6B,NSD2,XRCC4,EMSY,HPS4" Drug 4983_UP Daunorubicin hydrochloride [23541-50-6]; Up 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "SERPINA3,SYN3,NDRG2,SYT13,APLP1,ALDH4A1,ADAM15,LDLRAD4,CACNG1,RUNX1T1,RAB33A,CLCN4,HOMER3,CNTN1,CSF1R,CNTNAP2,RIMS2,RIPOR2,SGSM2,HS3ST2,SORBS3,MTSS1L,CD320,SEMA4D,ZNF44,LYVE1,GRM8,GUCY1A2,ITIH2,KCNB1,VWA5A,MID1,NELL2,NOVA2,NUCB1,P2RY1,PLXNB1,TCP11L1,ZFP2,FUZ,SYT11,PLCB1,CABIN1,OSBP2,LMF1,VSNL1,ZBTB14" Drug 5200_UP haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ADD2,AMH,APP,ASPH,ATM,AZGP1,BCL2L2,SCAPER,BAIAP3,ARHGAP33,CLGN,AKAP7,CRY2,PDE4DIP,CTH,RIMS2,PHYHIP,SRGAP3,KBTBD11,RASGRP2,CEND1,CACNG2,ALDH1L1,GLS,GNAO1,GUCY1A2,MDFI,MSI1,MTRF1L,POU3F4,RALGDS,ASAP3,CPEB3,CNKSR2,PREX2,LIMCH1,SNCA,DDN,INKA2,WSCD1,CRTC1,WIPF1,XRCC4,ZFP37,ZIC3,SCG2,SSPN" Drug 2495_DN Ethionamide [536-33-4]; Down 200; 24uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "NDRG2,SYNJ2,MTMR2,CFAP410,HIP1R,CD86,PLAA,CRY2,ABCG1,AATK,CSF1R,CSNK1E,SMG7,CNNM1,EIF5,EIF1,DLC1,CELF1,GALC,LILRB4,GRM1,ATXN2L,TJAP1,NCAM1,NUMA1,P2RY1,STRN3,CNNM2,CNTLN,PTPRN2,RAB3IL1,RAD52,MYH14,PAQR6,GALNT10,FAM214B,SLC11A1,SEPT8,KANK1,SYN2,DNMBP,KIAA1107,CRTC1,SYNC,PCBP4,UBE3B,ACTR3B" Drug 5348_UP Bisoprolol fumarate; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ALCAM,AMT,ANK3,APC,APOC1,PPP4R4,SLC4A4,BCL7A,CFLAR,GIT2,MFAP3L,G3BP2,SH3GLB1,KAT8,FHL1,GAD1,HBS1L,TXNL4A,HNMT,DHX35,INPP5B,KCNF1,KCNJ3,KHK,VWA5A,MAP4,MIA2,MMP16,MPP2,GIT1,NEK1,NNAT,STRN3,PMS2,MINDY2,SH3BP2,NLGN1,ANKRD6,BTBD7,ARC,RPGRIP1L,PSD3,RUNDC3B,ZNF24,GDPD5,HPS4,MPPE1" Drug 4073_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "TRMT9B,CDC42BPA,KCNAB2,APOC1,MARK4,ASTN1,BCL2L2,LARGE1,TAOK2,DNAJB5,ARMC8,BRINP1,ATN1,EZH1,F3,TUBB4A,DLC1,EFCAB2,PNMA2,C1QL1,GPER1,GUCY1B1,KIFC3,MGAT3,NOVA1,NOVA2,SLC11A2,NUMA1,CNTLN,PLPPR1,FAM120C,RAD51D,SH3TC2,MAPK12,SELL,SLC1A7,LHPP,MAPK8IP3,EXOC7,PCDHGA10,SYNE1,ARHGEF12,CRTC1,CABIN1,ZMYND8,NT5M,STMN4" Drug 4398_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ADCY6,BIN1,APC,EPB41L5,ATM,EIF4G3,STX16,CDK5R1,RAB29,SOCS6,DNAJB5,ABCG1,EDRF1,SMG7,ATN1,DTNA,APH1A,FGF13,FOXG1,SEMA4D,ATP2C1,MALT1,GLYR1,CACFD1,NR3C1,IL6ST,KCNF1,KIF2A,IPO5,MIA2,NF1,CNOT4,NUMA1,RETREG1,CEP97,RGS12,BTBD7,MAPK8IP3,PHLDB1,TBL1X,TCF7L2,PSD3,CRTC1,TK2,HIRA,VLDLR,WIPF2" Drug 6828_DN Piretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "DOC2A,BIN1,CDC42BPA,BCAS1,PPFIA3,MARK4,NCOA1,GYG2,BTRC,CACNA1D,CHM,PLAA,QKI,CSF1R,FAM169A,SDC3,RIMS2,RABGAP1L,DNM1,ERBB2,EXTL2,ZNF589,OGA,ERAP1,GLYR1,JAK2,MAPT,NOS1,CNOT4,PPP5C,RAD52,ZCWPW1,RGS10,RGS12,CCDC25,RPS6KA2,KIF16B,SLC9A5,COA1,ZCCHC24,KDM4C,PLCB1,ZKSCAN5,RPRM,VGF,MICAL1,HPS4" Drug 6345_DN Alverine citrate salt [5560-59-8]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ACLY,BRAP,BIN1,KCNAB2,ASPH,CLU,VCAN,SLITRK5,ARMCX2,EGFR,EZH1,F3,TUBB4A,SCML2,TESK2,CINP,GPD2,MAN1B1,DIPK1A,ZNF862,SLC11A2,SETD4,PIK3R1,PTPA,PID1,RAD51D,ROGDI,ZDHHC14,MAPK12,SH3BP2,EPN2,TTC17,FCHO1,SYT1,ATP13A2,CABIN1,TNS1,LMF1,XRCC4,TRIM9,TFIP11,PCBP4,ST7,PHTF2,TIGD6,AAAS,RNF146" Drug 327_DN arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ACLY,ADORA2A,SEMA7A,GAS7,DGKD,MARK4,ALDH4A1,CADM3,CFAP410,PTBP2,CHRNB2,TAOK2,CLCN4,NIPBL,PICK1,CNTNAP2,GREB1,TBC1D5,KLHL3,EPB41L2,LRRC23,STX2,TBR1,GJB1,HTATSF1,MCHR1,DIDO1,CACFD1,BTN2A1,SOX21,SCIN,KCNJ5,KHK,FXYD6,PC,PLCD1,LRRC49,PTPRN,FOXRED2,SH3BP2,ABLIM3,CDK5RAP2,SPTB,SEPT8,TRIM2,TF,UPF3A" Drug 6770_DN Oxybutynin chloride [1508-65-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ABHD6,ASPH,ATP6V0A1,CBFA2T2,MAGI1,SLIT2,HOMER3,ABCG1,ARHGEF10,CTH,CTNND2,DCAF8,SMG7,TRAPPC9,RBM12,FECH,KIAA1109,ANKFY1,INPP5K,TXNL4A,GLS,KIF2A,MAP4,MPP2,GIT1,ADAM22,NF1,NFYA,NNAT,PDE3B,PPP2R2B,NEK11,ZNF821,EPN2,SHANK2,SLC15A2,WDTC1,SPATA7,NCDN,TTBK2,TCF7,TNS2,TMOD1,VGF,LMF1,HPS4,PHTF2" Drug 5318_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ABR,ADCY6,BRAP,OGT,APC,NCOA1,EIF4G3,KRIT1,REPS2,FOXN3,NIPBL,RHOBTB1,DNM1,BSCL2,TESK2,ANKFY1,INPP5K,GHR,MALT1,NR3C1,RNFT2,SLC2A6,ARHGAP19,MMP16,SLC11A2,PLEC,PRKACB,USP47,RNASEL,FOXRED2,GALNT10,SMTN,KBTBD4,MAPKBP1,GLT8D1,KIF1B,ZBTB43,SS18,SYT1,TACC1,TCF7L2,TRIM2,SSBP2,HIRA,CADM1,LMF1,WIPF2" Drug 1441_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; HL60; HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ACTN2,AP1B1,PLA2G6,GAS7,SLC4A4,BMP7,SLC25A14,KYAT1,EPS15L1,CLCN3,TMEM184B,CRYM,SPOCK2,MED12,TRAPPC9,DNM2,EFNB3,SRPK3,SEMA4D,PCSK1N,KCNMB4,DIDO1,INPP5B,MBD1,MPP2,NEFH,NPPA,OGDH,CLDN11,PDPK1,PLCD1,CDIP1,CNNM2,RDX,C12orf49,SLC2A5,PEX26,SLC11A1,ZKSCAN3,WDTC1,ZBTB43,MAPK8IP3,DIP2A,GANAB,OBSL1,CHST5,ZNF189" Drug 5256_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "NDRG2,APOC1,ARSE,CADM3,BCL2L2,BAIAP3,RUNX1T1,USP2,CHRNB2,CLCN4,CNR1,PDE4DIP,HDAC9,MFAP3L,C2CD2L,LRRC23,ERCC2,CAMSAP1,SCARA3,TRMO,FUT9,GABRA2,GABRG2,GSN,ICA1,ITGA7,KCNN1,MSI1,ADAM22,SLC11A2,PIK3CD,PLCD1,MBOAT7,MAPK7,FAM120C,FAT4,TTLL7,ZNF821,STX1A,ZEB1,SLC35G2,RIMBP2,CDK20,FAM155A,UBE2H,UBE3A,MVB12B" Drug 1318_UP Metrizamide [31112-62-6]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ABAT,ALAD,PPFIA1,DNAH17,STX16,ATP2A2,SYNJ1,BTRC,CBR1,CLGN,SLC4A7,SMARCAL1,BAG4,RNF14,ZFYVE16,DBT,GSDME,RCAN1,HIPK3,FCF1,CELSR3,EPB41L2,PTK2B,ZNF589,CELF1,GALC,ARFIP1,HSF2,KPNA5,MAP4,NFYA,SLC11A2,PENK,PLEC,ZNF671,RASA3,PPM1E,IZUMO4,KDM4C,SS18,NXT2,PLCB1,TBCEL,TMPO,KAT6B,TSN,SLC17A7" Drug 866_UP ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ASIC1,MRTFA,CDC14B,ASPH,EIF4G3,GYG2,HOMER3,PDE4DIP,PPP6R2,ZNF337,CTIF,ATN1,DUSP9,LRRC23,CDKL3,F8,FAM198B,EFCAB2,FAM49B,FYB1,ERAP1,LPAR4,GRM8,HMGCR,LIG4,AFDN,LYRM9,PIK3CD,MAPK8,PTPRB,RAB3IL1,KHDRBS2,RGS10,KCTD17,ROM1,FUZ,NLGN1,KANSL3,ELMO2,ZNF415,ZBTB43,PLCB1,TK2,REEP1,EMSY,ZNF248,SSPN" Drug 6163_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ADORA2A,AMT,APAF1,SEMA4G,MARK4,BMP7,C5,CAPN3,ARHGAP33,EPS15L1,AKAP7,CPS1,SEC31B,ENTPD4,PPP1R16B,CTNND1,ARHGAP32,PLXNC1,STX2,GAA,SRCAP,GNG4,ATXN2L,TJAP1,MATK,NDUFA5,NEFH,NUMA1,ST8SIA5,PMP22,PRKAB2,RAB3A,ZDHHC14,TCP11L1,SEC14L1,MRAS,URGCP,MAPKBP1,KDM4B,DDN,DNMBP,CAMSAP2,TCF7,TCF7L2,XRCC4,NT5M,KAT6A" Drug 6247_UP Fluorometholone [426-13-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ASIC2,CDC42BPA,KCNAB2,BCAS1,APP,MARK4,ADAM23,CFLAR,SYNJ2,RAB29,ARHGEF2,CRLF1,CHN2,QKI,CTH,RIMS3,MFAP3L,KBTBD11,DTNA,SUGP2,EGFR,ACSL4,DLC1,FER,FHL1,B4GALNT1,GLYR1,GRIK5,IL6ST,KCNJ4,MDFI,MID1,POLG,CEP97,RAP1GDS1,RPS6KA2,WDR47,SMARCC2,SPTAN1,CDK19,NCDN,PSD3,TPM1,TRPC1,VLDLR,LRP8,MPPE1" Drug 4572_DN Cyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "RALGAPA1,MTUS1,APC,CDK13,ARHGEF1,CBFA2T2,PLAA,CLCN4,TPP1,QKI,CDC42BPB,SLITRK5,TBC1D5,RIMS3,DBT,FEM1B,EN2,EPHA5,DENND4A,FECH,CAMKK2,INPP5K,C1QL1,MAP4,CNOT4,PDPK1,PRPH,RIPOR1,RAB3IL1,ATG16L1,RPS6KA2,SAFB,SUPT20H,AMBRA1,PDZD2,KDM4C,ZBTB43,TROVE2,CEP68,KIAA1107,TCF7L2,ARHGEF12,TPM2,VIPR2,LAT2,PHTF2,AAAS" Drug 6058_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "AMPD3,GAS7,CDK13,ATP1A3,CACNA1G,CDH2,ADGRG1,CBARP,DNAJB5,FAM149A,RIPOR2,SNPH,SPOCK3,DUSP9,SRPK3,MTSS1L,ZNF391,FHL1,ZNF44,GAD1,GAP43,GNAL,GPM6B,GRK4,GRM8,ATXN2L,IRF8,KCND3,KCNN1,LAMA2,MDFI,NTRK3,OLR1,SAMD9,EMID1,SLC1A7,SLC11A1,SOX2,KIF21B,ARHGAP26,WSCD1,TPM2,FLRT1,VLDLR,KCNAB1,PARP11,JPH3" Drug 5329_UP Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "ADD1,AP2A2,APC,APLP1,APOC1,CDK13,ATM,ST3GAL5,LDLRAD4,CBR1,CLGN,NRG2,PDE4DIP,KIAA0513,GIT2,DLG3,FEM1B,KIAA1109,FGFR1,TXNL4A,GRB10,KCNH2,KCNJ3,MAP4,MAPT,NACA,NEK1,NF1,NFYA,SERPINE2,PMS2,RGS3,FNDC3A,ANKRD6,KANSL3,SLC20A2,ERC1,ATP10B,TCF7L2,PSD3,TMPO,PARD3,TRIO,PLPPR2,VAV2,DNALI1,C12orf4" Drug 524_DN nordihydroguaiaretic acid; Down 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "RALGAPA1,ACADM,ASIC1,NDRG2,ARHGAP5,ASCL1,MARK4,ZBTB10,CNOT8,AKAP6,SH2B1,AATK,CTNND1,DLG3,FEM1B,SIDT2,EFNA3,VPS26C,EZH1,FGR,PRKAG2,ZNF638,GNG4,ADAMTS13,CACFD1,IDH3A,BRINP3,LAMP2,NRGN,SETD4,PDE3B,RETREG1,PLCD1,PMS2,PACSIN1,PPP3CB,ZSCAN32,ATXN1,ZNF821,FAM214B,KBTBD4,KDM4B,ZHX3,NMNAT2,DIP2A,TMEM121,DNAJC12" Drug 4960_UP Miconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.48E-03 1.00E+00 9.75E-03 1.11E-01 47 195 "PLA2G6,C1QTNF1,CNTNAP1,FAM131A,AZGP1,CACNA1I,BAIAP3,EPS15L1,CLTB,COL9A3,CSF1,SUSD5,SDC3,SNPH,MYEF2,RUSC2,CDON,ST8SIA3,SIDT2,RCAN2,LRRC17,GNAS,LPAR4,GRM8,GSTM5,KCNMA1,KCNN1,VWA5A,NOVA2,OPCML,KCNK10,RETREG1,PLP1,GAL3ST4,TCP11L1,SLCO1A2,KIF21B,ZC3H13,SYT5,POPDC3,SEZ6L,VIPR2,WIPF1,LAT2,XRCC4,DNALI1,SCG2" Drug CID006448119 Chr 5 Stitch 1.48E-03 1.00E+00 9.75E-03 1.11E-01 33 125 "SLC12A5,ATP1A2,BLM,CDR1,CLGN,CHGA,AKAP12,DPP6,EN2,FDFT1,GABRA2,GABRA4,GCK,GCNT2,PPARGC1A,HTR5A,IGF1,KITLG,NF1,NRGN,PHKG1,CAMKV,IRX1,RELN,PTCH1,SLC12A4,SYT1,TAC1,ZFPM2,THBS4,ZNF346,VLDLR,TUBA1A" Drug ctd:C045950 propiconazole CTD 1.48E-03 1.00E+00 9.80E-03 1.12E-01 306 1668 "NDRG2,FMNL2,ADCY6,ADD1,PLEKHH1,ADRA1B,KLHL13,PLA2G6,ALCAM,BBOX1,EP400,ANXA7,APBB2,DGKZ,ALS2,APP,CDC14B,MIER1,CDK10,PDXK,MADD,ARRB1,ASPH,DDX3Y,DYNLL1,ATM,ATP1A2,ATP2A2,ATP2B2,BID,PROM1,LDHD,ST3GAL5,CA8,CAMK2B,CANX,CARS,CBR1,CBS,RGN,SCARB1,ZNF445,MAGI1,FOXN3,CNOT8,PLAA,CLCN3,CLCN4,NMT2,CLTB,NGEF,TJP2,QKI,TMEM184B,HECTD1,NIPBL,TBPL1,AHCTF1,ACBD5,NSL1,CHD1L,NECTIN3,FAM171B,C2CD2,CREM,RBM39,CRY2,NCOR2,GDA,FEZ2,CSNK1E,GREB1,USP6NL,GAPVD1,DCAF8,LONRF1,TM9SF4,MAML1,TOMM20,IP6K1,SIRPA,DBT,DCT,CEP170,BLOC1S6,ZC3H11A,DDX46,RHOBTB1,G3BP2,MTX3,FAM107B,CPEB2,RCAN1,ARRDC4,GOLT1B,SGK2,OPTN,MBNL2,AASS,EIF4G2,PAN3,EIF1,PIPOX,EXTL1,ADGRV1,F5,WAC,SH3YL1,PTK2B,TAOK3,DLC1,RACK1,FDFT1,FGF1,FGFR3,SEC23B,VTI1B,FOXM1,FOXO3,SORBS1,USP16,UFM1,CAMKK2,CELF1,CSPG5,SARAF,GAB1,NEK6,NCKAP1,INPP5K,CPLX1,GBX2,GHR,PPARGC1A,RUNDC3A,RNPS1,TNRC6A,GLUL,GPT2,PRRC2B,RAPGEF4,DIDO1,NR3C1,GSTT2,FICD,PSIP1,MUM1,HBA1,PACSIN2,HLF,ELOVL5,HMGB1,HMGCR,HNMT,HNRNPK,LRRC75A,HSP90AA1,IGF1,IL11RA,INPP5B,ITIH2,JAK1,SLC35G1,KCNK1,TTYH2,STMN1,LIG4,HECTD2,FGFBP3,ARHGAP12,SMAD1,PIK3AP1,GPR155,ADAM11,CHIC1,MKLN1,NRBP2,THYN1,MTTP,NFIA,NFIX,NUMA1,PAH,PAX6,PBX1,PC,PCDHGC3,PCSK5,PDE2A,PFKFB3,ABCB1,SERPINE2,PIK3R1,SNX10,ZFYVE21,RETREG1,PLEC,EPN1,PLTP,ASPDH,PLXNB1,PSAT1,RETREG2,SEPT4,PPARA,MINDY2,PPM1B,PPP3CA,RASGEF1B,CEP41,MAPK3,PROX1,MASP1,RELN,BCAS3,PSMA6,ANKHD1,PTH1R,PTPRD,PEX5,RIPOR1,SUSD4,RBBP8,RGS12,SEC61A2,PBRM1,ZFHX4,CYB561D1,TMEM206,PCMTD2,FBXW7,ZC3H14,ACER3,PTGR2,ST6GALNAC6,ATXN1,ATXN2,TNFRSF19,SMPD3,SFPQ,TRA2B,HSPA4L,SGK1,KIF16B,AMBRA1,ST3GAL3,SLC2A5,PEX26,RAB3GAP1,SLC20A2,CPEB4,ABTB1,SMARCA4,PALLD,TMCC1,SON,WDTC1,SOX5,ZCCHC24,ZHX3,KIF1B,LHPP,SRPK2,TAB2,PBLD,SMOC1,NXT2,NEK4,NSFL1C,FAM168A,PRRC2C,COBL,TACC1,SEMA4A,ATMIN,ZEB1,PUM2,TNS2,SIK3,TF,ENHO,NACC2,TK2,LRRC8A,TMPO,TNS1,TSC1,TST,TTC3,TUBB2A,BCL2L13,SLC13A3,ETNPPL,XPO1,SPHK2,ZBTB16,MAP3K12,EVI5,RNF103,HPS4,ITM2C,PCBP4,RTN4,CERS6,RNF170,SPATA13" Drug CID000005052 3-isoreserpine Stitch 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "ABCF1,ACHE,ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRA1D,ADRA1B,ADRB2,ABCD2,AMT,API5,CACNA2D1,CCK,CHGB,CHRM1,ABCG2,ABCG1,DRD1,ABCC5,ABCC9,EDNRA,EDNRB,ABCA8,PRMT5,OLFM1,GFER,LOXL3,HTR2A,KCNH1,MAOB,NPY,PENK,ABCB1,PIK3C2A,PIK3CD,PIK3R1,SCG5,SMARCD3,VPS13A,NUDT10,MLST8,TGFBR3,TRH,SCG2" Drug 1550_UP Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; HL60; HG-U133A Broad Institute CMAP Up 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "APBA2,MARK4,NRP2,SCAPER,CD86,ARHGAP33,SH2B1,PPP1R16B,ATN1,SIDT2,FAM13A,PHF20L1,ENO2,DMTN,IGSF6,F3,ALDH1L1,PCDH17,GNAO1,PRRC2B,IFI16,ITGAM,NCF2,RETREG1,PLCD1,SLC25A23,PPP2R5C,SAMD9,PTAFR,RGS12,ARHGEF10L,RNASE1,MYH14,FBXW7,ZNF671,SGK1,SH3BP2,SLC6A8,HECW1,SPP1,SAMSN1,PDLIM2,WASHC4,CLDND1,CAMK1G,ACTR3B" Drug 4306_DN Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "RALGAPA1,NME5,ATM,ATP2B1,SRSF11,B4GALT6,ABI3BP,ENTPD4,ARHGAP24,NR1D2,DTNA,EDIL3,ING4,FER,FGF13,SPIN1,HTATSF1,NR3C1,HAS2,AGFG1,IFI16,IL6ST,MAP4,MIA2,NFIX,STRN3,LRP12,PKN2,SLC25A36,KIRREL1,ATXN1,TNIK,ZBTB43,TTBK2,TBL1X,EHBP1,PSD3,DICER1,TMPO,SF1,ZNF24,ZBTB38,WNK1,PRDM2,EVI5,KAT6A" Drug 3833_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "BIN1,CHM,TAOK2,AKAP7,RIMS2,DAPK3,MBNL2,PLEKHA1,PLEKHO1,LRRC23,VPS26C,KIAA1109,BAIAP2,FHL1,ANKFY1,GPR153,GAB1,INPP5K,GLYR1,GPD2,MAP4K5,INPP5B,MBD1,ADAM22,NEK1,NFYA,NPR2,ODF2,SERPINI1,PLCD1,PLEC,RAB3A,RAD52,ZDHHC14,RGS12,GSTCD,EMID1,ASAP3,FUZ,ELMO2,WDTC1,SPTAN1,ARHGEF12,TRIO,ZKSCAN5,MAP3K12" Drug 999_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "NDRG2,OSBPL1A,AMPD3,APP,ZFYVE9,SLC4A8,LRIG1,FAM169A,SEC14L5,DOCK4,ARMCX2,MFAP3L,RABGAP1L,EPHA5,ZNF589,BAIAP2,B4GALNT1,DIDO1,NR3C1,IL6R,ADAM22,NAP1L2,PDE4A,MBOAT7,MAPK8,RAB3A,RALGDS,RGS10,RNASEL,HSPA4L,SH3BGR,LIMCH1,MAPKBP1,ZCCHC24,ZNF423,ATP10B,TROVE2,SSTR2,MAPK8IP3,TRIM2,R3HDM1,CABIN1,AMACR,VLDLR,WNK1,FXR1" Drug 7405_DN Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "AP2A2,MTUS1,ATM,SYNJ2,CA12,AP4M1,EPS15L1,CLCN3,GREB1,RHOBTB1,SGSM2,DLG3,RASGRP1,EGR3,PCOLCE2,PLEKHO1,EPB41L1,OLFM1,BAIAP2,TMEM164,SMC2,ATP2C1,GPR19,MAP4K5,IL6ST,JAK2,ODF2,OGDH,PC,PFKFB3,PIK3R1,FAM216A,SMOX,ING3,SUSD4,RET,SGK1,AMBRA1,PEX26,RCOR3,MYCBP2,CEP68,SATB2,TRIO,HIRA,SF1" Drug 5821_UP Tetrandrine [518-34-3]; Up 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "MTUS1,PPFIA1,APBB2,LGR5,ARNTL,ALDH4A1,ST3GAL5,C5,IL33,CDC42,AKAP7,SUSD5,VCAN,CTH,FAM13A,TENM1,MRNIP,PLEKHO1,RRAGB,NRN1,FDFT1,GABRG2,GLRB,TDRKH,HMGCR,AFDN,GIT1,MT1M,TAGLN3,NTRK2,MAPK8,GDPD2,SUGCT,MYH14,NEK11,TCP11L1,ASAP3,FAM214B,IFT122,IQSEC2,SYT1,KIAA1107,TNS1,HIRA,CLDND1,PARP6" Drug 4437_UP 17-DMAG; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.49E-03 1.00E+00 9.86E-03 1.12E-01 46 190 "KCNAB2,ARRB1,KIF1A,CBS,CLU,AKAP6,WHRN,CSF1,CHD5,CTH,EDRF1,BRINP1,ST8SIA3,EDN1,IGSF6,REEP2,BAIAP2,CAP2,GRIK2,SPACA9,GRIN1,CACFD1,GRM3,HRH3,SYNPO,MAP2,MDFI,NF1,OXTR,TREM2,PDE4B,PGAM2,PTPRN2,RFX2,RGS4,RGS12,SYNDIG1,HSPA4L,ST6GAL1,PDZD2,TSPYL2,TACR1,EXOC7,ZIC3,SLC17A7,NUP214" Drug CID006445562 EKB-569 Stitch 1.50E-03 1.00E+00 9.90E-03 1.13E-01 25 87 "CLK4,BTK,CSNK1E,DAPK3,EGFR,TNK2,EPHA5,EPHB1,ERBB2,ERBB4,FER,CAMKK2,FYN,MAP4K5,MYLK2,JAK2,KIT,LSS,PHKG1,MAPK3,PTK2,RPS6KA2,TNIK,TEK,EPM2A" Drug CID000004456 neostigmine Stitch 1.50E-03 1.00E+00 9.90E-03 1.13E-01 25 87 "ACHE,ADRA1B,ADRB2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,BCHE,CHRM1,CHRNA4,CHRNB2,DMPK,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,CCDC80,PEG10,SST,PRDM2" Drug CID000008082 piperidine Stitch 1.50E-03 1.00E+00 9.91E-03 1.13E-01 34 130 "ACHE,ADRA1D,BCHE,CHRM1,BOC,GPRASP1,HDAC4,PHF19,DMD,SLC29A4,F3,PNMA2,B3GAT1,HPGDS,POLL,MCHR1,GRIN2C,GRIN2D,HRH3,HTR2A,KCNA4,KCNH2,MTTP,OPRL1,PTCH1,PEX2,PEX5,QDPR,PEX26,CLSTN2,TAC1,TACR1,SMUG1,FTSJ1" Drug 7389_UP 0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.51E-03 1.00E+00 9.96E-03 1.13E-01 45 185 "ABHD6,GRAMD1B,NME5,APBB2,CDK10,PPP4R4,CADM3,CDK5R1,MAP7,FOXN3,TAOK2,WHRN,CREM,SDC3,CTH,PITPNC1,DUSP9,EDN1,EFNA3,LPAR6,MRNIP,CDKL3,DLC1,PRELID3A,ZNF276,GLYR1,TJAP1,DIPK1A,KCNMA1,CLDN11,PLCD1,SMOX,SMIM7,FA2H,PPP5C,RAB3A,RAD52,RPS6KA2,SLC8A1,TNIK,PHLDB1,ARHGEF12,CRTC1,MPPE1,PLSCR4" Drug 7402_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.51E-03 1.00E+00 9.96E-03 1.13E-01 45 185 "ARID1A,ADCY6,CDC42BPA,KCNAB2,GAS7,NRP2,SYNJ1,CARS,ARHGEF2,PLEKHB1,TAOK2,CTNND2,EXOG,DPH1,EFNA3,PLEKHO1,COQ7,CDKL3,EZH1,DLC1,ST3GAL6,TESK2,FYB1,CSDC2,C1QL1,ZNF276,GLRB,HMGCR,TJAP1,MIA2,MMP16,CNOT4,PLCD1,TMEM231,C1orf54,ARHGEF10L,FUZ,ARHGEF40,SLC20A2,ARFGAP1,DDN,MAPK8IP3,ZKSCAN5,XRCC4,KCNAB1" Drug DB00753 Isoflurane Drug Bank 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "CALM1,ATP2C1,GABRA1,GRIA1,KCNA1" Drug CID000441159 AC1L9ANR Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "CDO1,CDON,BCO1,PPARA,RXRG" Drug CID000129517 MS-857 Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ALDH7A1,CALM1,KRIT1,PDE2A,PDE3A" Drug CID005289517 thio-ATPA Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "GRIA1,GRIA2,GRIA4,GRIK1,GRM3" Drug CID000008163 2-undecanone Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "HPGDS,KCNH1,PCSK5,RDX,TMEM132D" Drug CID000119072 vioxanthin Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "CD86,MAPK3,MAPK9,MAPK10,GORASP1" Drug CID000196939 Men 10573 Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ELAVL3,B3GAT1,TAC1,TAC3,TACR1" Drug CID000155672 AC1L4ERC Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ACHE,CHRM1,DMPK,PNMA2,MT3" Drug CID000012959 dimethyl phosphorodithioate Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ACHE,BCHE,DMPK,DMTN,PIK3C2A" Drug CID005460582 nitroxide Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "CLTC,PNMA2,PAX6,SYNE1,ARHGAP9" Drug CID000092956 DPhP Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "DMPK,POLK,PC,SCP2,TP53BP2" Drug CID000068460 aureothricin Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "TAOK1,TAOK2,PTK2B,ITGAV,PTK2" Drug CID000196940 Men 10612 Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ELAVL3,B3GAT1,TAC1,TAC3,TACR1" Drug CID000104788 gonyautoxin II Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "NKX6-2,CIT,KIT,TRERF1,ST8SIA2" Drug CID000145939 Phorphin Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "CCK,PDYN,PENK,CLIP1,CLIP2" Drug CID000068410 "2-methyl-1,2-propanediol" Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "APPL1,MTR,GSTCD,SCN2A,FAIM2" Drug CID000032832 3-nitropropanol Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "AASS,DNER,GPD1,GPD2,ADHFE1" Drug CID006449836 TZC-5665 Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ALDH7A1,CALM1,KRIT1,PDE2A,PDE3A" Drug DB00277 Theophylline Drug Bank 1.52E-03 1.00E+00 1.00E-02 1.14E-01 5 7 "ADORA1,ADORA2A,PDE3A,PDE4A,PDE4B" Drug CID000388647 AC1L8WBM Stitch 1.52E-03 1.00E+00 1.00E-02 1.14E-01 35 135 "SYN3,ACTN1,ADRA1B,DYNLL1,CBFA2T2,CLU,CLTB,CNR1,SLC32A1,SLC25A18,ELAVL3,ERBB2,TLR7,NRG3,GRIA1,GRIA2,GRIA4,NR3C1,MAP4K5,HPS5,SYNPO,HSP90AA1,IL12A,KITLG,PIK3R1,SLC6A11,SLC14A1,ERC1,SSTR1,SYN1,SYN2,PJA1,THRA,TK2,FXR1" Drug 5203_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.53E-03 1.00E+00 1.00E-02 1.14E-01 44 180 "BIN1,DNAH17,ST3GAL5,SOCS6,CLU,DNAJB5,NECTIN3,CRY2,EDRF1,RCAN1,EFNB3,MBNL2,KIAA1109,SEMA4D,SORBS1,GRB10,DIDO1,CACFD1,NR3C1,ICA1,KCNQ3,ZNF862,NAP1L2,NDUFA5,NF1,NUCB1,OXTR,PLCD1,MBOAT7,KLK6,MORC4,HSPA4L,SGK1,SH3BGR,ITSN1,DOCK10,FAIM2,ZCCHC24,TSPYL2,ZEB1,ARHGEF12,LAT2,XRCC4,FXR1" Drug 5590_UP thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.53E-03 1.00E+00 1.00E-02 1.14E-01 44 180 "KIDINS220,AGT,AMT,CNTNAP1,APAF1,CAMK2B,CRMP1,CSF1R,CNTNAP2,RIMS2,SPOCK2,SLC12A6,DRD1,EFNB3,IGSF6,FGF13,EFCAB2,GAD1,ERAP1,GRIK1,NR3C1,GUCY1A2,HRH3,IRF8,NCAM1,SLCO1C1,ENPP2,GPR85,CDK14,MINDY2,LRRN3,ELOVL2,RGS4,KCTD17,TTLL7,SLC11A1,CDK19,PLCB1,SYP,SYT5,WSCD1,TRIM2,TRIO,WIPF1" Drug CID000009528 flurothyl Stitch 1.53E-03 1.00E+00 1.01E-02 1.15E-01 16 47 "ABAT,PDXK,CA4,DLG4,EEF1A2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIN1,GRIN2C,GRIN2D,TSC2,SLC30A3" Drug ctd:C057416 KT 5720 CTD 1.53E-03 1.00E+00 1.01E-02 1.15E-01 16 47 "PLA2G6,APP,CHRM1,FGF1,GPER1,GRIN1,ITGAM,KCNC2,NOS1,NPPA,NUCB2,ABCB1,MAPK3,SLC1A2,SNAP25,SIRT1" Drug CID000784625 5-(2-chlorophenyl)-2-furoic acid Stitch 1.53E-03 1.00E+00 1.01E-02 1.15E-01 16 47 "METAP1D,SLC12A5,CD81,ABCG2,FKTN,GOLGB1,GRIK4,NEFM,NEFH,NTRK2,RELN,RDX,SLC12A2,TSC1,TSC2,BEST1" Drug ctd:C012606 4-vinyl-1-cyclohexene dioxide CTD 1.55E-03 1.00E+00 1.02E-02 1.16E-01 42 170 "ACHE,PLA2G6,AMH,ARHGAP5,KSR1,FOXN3,DAPK1,SIRPA,DLG4,DNM1L,TSPAN5,EGFR,EIF4G1,ELAVL2,GHR,GRB10,RAPGEF1,PTPN5,ITGAV,JAK1,KLC1,LIMS1,NFIA,PDGFRA,PIK3C2A,MED1,PPP2R5C,PRKAB2,PRKACB,PRKAR1B,MAPK8,PTPRG,TNFRSF19,SFPQ,KIF1B,MAPK8IP3,MLST8,SIN3B,TGFBR3,TTC3,UBE2H,KCNAB1" Drug CID000548548 AC1LC61J Stitch 1.55E-03 1.00E+00 1.02E-02 1.16E-01 19 60 "ABAT,CDO1,NPIPA1,GDA,ACOT8,DTNB,PNMA2,PCSK1N,GRIK1,GRM1,GRM2,GRM5,GRM8,SOX21,OLR1,OMG,RNH1,SPTB,MSRB3" Drug 1786_UP Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.56E-03 1.00E+00 1.02E-02 1.17E-01 39 155 "NDRG2,ADD3,ADORA3,BIN1,ARRB2,CFLAR,LDLRAD4,CREM,PPP1R16B,DOCK4,HP1BP3,GOLT1B,MBNL2,EIF5,ING4,DCTN4,ACSL4,GLUL,IRAK3,AGFG1,ITGAV,ARHGAP12,AFF1,PDE3B,PDE4B,PDE4D,SATB1,ATXN7,SEC14L1,SGK1,FNDC3A,SLA,SLC12A2,ELMO2,SAMSN1,CEP68,SSBP2,FLRT2,ZBTB16" Drug CID000123797 Neuropeptide Ff Stitch 1.59E-03 1.00E+00 1.04E-02 1.19E-01 21 69 "ASIC2,ASIC1,CCK,ASIC3,PPP1R1B,FGR,GAD1,GALR1,GNAO1,PRLHR,GPR17,GPR26,GRIA2,KCNJ3,KCNJ5,NPY,OPA1,OPRL1,PDYN,PENK,SST" Drug CID000005619 AC1Q3O8K Stitch 1.59E-03 1.00E+00 1.04E-02 1.19E-01 26 92 "AP1B1,CACNA2D1,CCK,CCKBR,KRIT1,CNR1,SIRPA,CEP170,DNM1,DRD1,FOXM1,GRIN2C,GRIN2D,GABARAPL2,KCNJ3,KCNJ5,NME4,NPY,OPCML,OPRL1,PDYN,PENK,GSTCD,SST,TPM3,P2RY12" Drug CID000008420 2-naphthalenesulfonate Stitch 1.59E-03 1.00E+00 1.04E-02 1.19E-01 26 92 "AMT,EIF4G3,SCARB1,CHGA,CHGB,COL11A2,DRD1,EIF4G1,EIF4G2,ERBB2,NEU3,CNDP1,GRIK1,GRIK3,GRIK4,HMX1,HSD17B1,KCNK1,SCG3,RBBP8,SMARCA4,STAU1,SLC13A3,SMARCAD1,UPF3A,SCG2" Drug CID000004862 AC1L1J4H Stitch 1.60E-03 1.00E+00 1.05E-02 1.19E-01 11 27 "TUBD1,TUBB3,TUBB4A,DNER,TUBA8,TUBA1C,TUBB2B,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000004450 nefopam Stitch 1.60E-03 1.00E+00 1.05E-02 1.19E-01 11 27 "ASIC1,ASIC3,HRH3,S100B,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,SP2" Drug CID004627981 AC1NDLZU Stitch 1.61E-03 1.00E+00 1.06E-02 1.20E-01 15 43 "ALDH7A1,CS,NCAN,TRAPPC9,CASP8AP2,AASS,GABRG2,CIT,KCNC1,KCND3,KCNIP2,ITPRID2,SST,RGL1,PDLIM2" Drug CID000003698 amrinone Stitch 1.61E-03 1.00E+00 1.06E-02 1.20E-01 15 43 "ADCY5,ADCY6,ADCY8,ADRB2,ALDH7A1,CACNA2D1,LRBA,CFL2,NAP1L2,PDE2A,PDE3A,PDE3B,PDE4B,PDE4D,PRKACB" Drug CID000169313 3-(2-carboxyindol-3-yl)propionic acid Stitch 1.61E-03 1.00E+00 1.06E-02 1.20E-01 15 43 "TNK2,GLRB,HP,HPR,NTRK2,NTRK3,PKM,SP2,SP4,TK2,TNFRSF1B,TPM1,TPM2,TPM3,TPM4" Drug CID000065167 POPC Stitch 1.63E-03 1.00E+00 1.07E-02 1.22E-01 68 306 "ACLY,ABHD6,PLA2G6,SYT13,AMPD2,AMPD3,ANK1,ANXA7,DGKZ,GPAM,DGKD,APOC1,APOC2,SPTBN4,PLA2G4C,CERS5,SCARB1,DGKI,FADS2,PCYT1B,ABCG1,PLCXD3,PNPLA8,DGKB,DGKG,PITPNC1,CHRDL1,DTNB,RBM12,F3,FOLH1,STARD10,NEU3,LOXL3,PLCD4,ACOT7,MAOB,MAT2A,MBP,NOVA2,PCDH8,GPR85,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PLP1,PLTP,PRKCB,PRKCG,PRKCZ,SCP2,SMPD3,SLC12A4,SPTAN1,PLCB1,TBL1X,PIK3R5,TPD52L2,TTPA,PITPNB,PLPPR5,SLC30A4,SCG2,PLD4,NETO1" Drug ctd:D010424 Pentobarbital CTD 1.64E-03 1.00E+00 1.07E-02 1.22E-01 31 116 "APAF1,APP,CACNA1I,CCK,CNR1,FOLH1,GABRA1,GABRA2,GABRA4,GABRB1,GABRB3,GABRG2,GAP43,GFAP,GJB1,GNAO1,GNAS,GRIA2,GRIN1,GRIN2C,KCNH2,NPY,NPPA,NTRK3,PDYN,PENK,ABCB1,MED1,MAPK3,TRH,UCHL1" Drug ctd:D005472 Fluorouracil CTD 1.64E-03 1.00E+00 1.07E-02 1.22E-01 254 1364 "ADD3,MTUS1,ALCAM,BCAR3,AMPD2,AMT,EP400,APAF1,APBA2,APBB2,UPRT,APOC1,PDXK,ZSCAN18,ZNF582,BID,BLM,CFLAR,PROM1,CDK5R1,DST,GYG2,SGCE,CA12,CALB2,CANX,PRC1,CBS,AIFM1,CD38,LRBA,CDC25B,DCLK1,TBRG4,NOG,ADGRG1,RCBTB2,SRSF11,FOXN3,PLEKHB1,CHRNA4,CLCN3,TPP1,CLTC,ABCG2,TMEM184B,MAGED1,CP,SEC31B,PREPL,CRHBP,AKAP12,NCOR1,NCOR2,CSF1,CSNK1E,KIAA0040,CTNND2,PUM1,HDAC4,DAPK1,DCC,DCT,ALKBH8,FAM107B,NR1D2,ABI1,PDCD6IP,GNE,ABCC5,EDIL3,EDN1,EDNRA,OPTN,EGFR,ABI2,LPAR6,EIF5,PCOLCE2,ELN,TUBD1,OLIG2,PLEKHO1,SRRM1,ERBB2,ERBB4,ERCC2,TMEM74,F3,F8,ARMCX1,TUBB3,TAOK3,DLC1,PPP1R1B,OLFM1,MAD2L2,PRKAG2,CAP2,SYNCRIP,AGAP3,FOXO3,FLT1,PDLIM5,PNMA2,FYN,GABRB3,NEK6,IQGAP2,SEPT9,GART,DNER,TUBA8,GDF1,SESN1,GFAP,GFRA1,MALT1,DBF4,CBX1,FERMT2,PSRC1,GP1BB,KIF3A,AP4S1,GUCY1B1,MAP4K5,ATOH8,HBA1,ELOVL5,HAPLN2,ACOT7,IFI16,IGF1,RBPJ,ITGAV,KCNQ2,KHK,KIT,L1CAM,TTYH2,LIFR,LSS,MAP2,MAPT,MBNL1,MBP,MDFI,MDM4,KITLG,MT1M,MXI1,MYCN,MYO6,NASP,NBL1,NEK1,NEUROD1,NFE2L2,NFYA,NME4,NODAL,NPPA,NTRK2,GPR137C,PAX6,ABCB1,SERPINE2,ANLN,SMOX,SLC25A23,PURG,MAPKAP1,EXOSC10,POLG,PPP3CA,KANSL1,PRKCZ,MAPK3,MAPK7,KLK6,SYTL2,LAMA1,PTCH1,PTK2,NKAIN1,RDX,RGS4,ZNF532,SETD5,MCMBP,LGR4,RTKN,SCN2B,SEC14L1,MRAS,ITSN1,FAM102A,SHMT2,R3HDM2,SEC31A,SEPHS1,ELMO2,EFHD1,ARFGAP1,ZKSCAN3,ANKRD36,KDM4B,SOX2,FNBP1,EMC1,UNC5B,PEG10,DBNDD2,MESP1,SST,EPB41L3,INKA2,MPRIP,STAU1,NEK4,KLHL7,SYP,MMS19,TCF7L2,TRIM2,PCDHA5,TEK,DICER1,LEFTY2,ZMAT3,TGFBR3,TK2,TNFRSF1B,PARD3,TNNT1,SEZ6L,TPM1,STXBP4,ZMYND8,CA14,TSC2,TST,UCHL1,UGT8,FLRT2,LMF1,ZNF32,NT5M,LRP8,ADAMTS9,SCG2,VANGL2,NETO2" Drug 3761_UP Flecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADD2,SEMA6A,AMH,BCAS1,CDK10,BRINP2,ATP2B2,FUBP1,C5,BAIAP3,CDO1,TOX,EFNA3,ING4,ELAVL3,REEP2,OLFM1,GATM,RND1,SPACA9,GRIK5,GRM8,ITIH2,KCND2,KCNMA1,AFDN,ADAM22,NPY,PURG,TNPO2,PPP2R2B,PTAFR,PTPRO,ZNF821,CPEB3,DOCK10,CNKSR2,SLC8A1,ZC3H13,NCDN,TAC3,MCF2L,OBSL1,PCDHA6,TMOD1,FLRT2,KCNAB1" Drug 499_DN "novobiocin sodium, USP; Down 200; 100uM; ssMCF7; HG-U133A" Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "NDRG2,OGT,NCOA1,N4BP2L1,ATP6V0A1,RGS11,SLC25A14,MAP4K4,ARHGEF6,DAPK3,DRP2,DTNA,FEM1B,SIDT2,PLEKHO1,ERCC2,F3,RASL10A,HPGDS,MAN1B1,SYNPO,MAOB,MARK1,MATK,FXYD6,NLE1,PNMA3,MAPK7,NKAIN1,ARHGEF10L,RNASE1,FAM192A,ITSN1,SNCA,TNIK,TSNAXIP1,DBNDD2,CLASP2,ELOVL4,EXOC7,ARHGEF12,TF,SEZ6L,HIRA,GDPD5,MPPE1,MVB12B" Drug 6772_DN Piperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "APC,EPB41L5,PPFIA3,BCL7A,CDK5R1,BTRC,SYNGR3,PLAA,QKI,NCOR1,MICAL2,MFAP3L,SMG7,DTNA,SIDT2,ELAVL3,VPS26C,FHL1,B4GALNT1,SRCAP,GFER,GLS,GRB10,KHK,MEIS1,LYRM9,NEK1,NFYA,CNOT4,ODF2,PDE3B,RETREG1,RAD51D,PAQR6,SH3BP2,SHANK2,WDTC1,NXT2,TNS2,BEX4,PARD3,HIRA,WRN,EMSY,MFF,UBE3B,PHTF2" Drug 3263_UP Piperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "LTBP4,ANK2,APBB2,ASPH,CAMK2B,RUNX1T1,CHRNB2,DNAJB5,WHRN,MFAP3L,DNM1,DUSP9,SNX29,ING4,DMTN,F3,GLYR1,GLS,GNAS,MAN2A2,MAPT,MDM4,MEIS2,KITLG,MMP16,TAGLN3,NOS1,NUMA1,PDE3B,PLCD1,C1orf54,ZCWPW1,RFX2,RPS6KA2,SH3BP2,ZNF365,CCDC88A,HECW1,ARHGAP26,ZEB1,OBSL1,ZNF34,UBE3A,ZFP37,SPHK2,SYNC,UBE3B" Drug 1494_DN Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABAT,PKP4,FAM131A,PPFIA3,ARRB1,CFLAR,BTRC,SPAG9,NIPBL,DBT,HIPK3,CNNM1,SCML2,EFEMP1,COPS8,HTATSF1,GNG4,HSF2,MIA2,SETD4,PIK3R1,CCSER2,STRN3,LRP12,MED1,MAPK3,VPS13C,C1orf109,PEX5,RAB3IL1,MAP6D1,FNDC3A,EPN2,BTBD7,RCOR3,MAPKBP1,ZNF302,ATP11A,TBL1X,AHCYL2,ZNF34,HIRA,ZBTB14,ZNF23,ZNF184,PHTF2,SSPN" Drug 2706_UP Vidarabine [5536-17-4]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "TKTL1,ACTN2,ANK2,KSR1,SYNJ1,HAP1,HAPLN1,SIPA1L1,EDNRA,ELN,VPS13B,LRRC23,RASGRP2,ERBB2,TUBB4A,PRELID3A,GAA,GAB1,GLRB,GNAS,STON1,PCLO,SPACA9,MOBP,LYRM9,MYO7A,KCNK10,PDE4D,PPARA,DCHS2,SYTL2,RGS12,SYNDIG1,SH3BGR,RPH3A,ZNF415,ZC3H13,IQSEC2,ATP10B,PLCB1,SYT1,PCDHGA10,DOCK9,CHST8,TLR4,TRIO,SLC17A6" Drug 2547_UP Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADRA1D,C1QTNF1,AMH,ASCL1,B3GALT2,CADM3,KIF1A,CACNB4,BRSK2,CHRNA4,EPS15L1,NRXN3,RAB26,PDE4DIP,NOS1AP,PHYHIP,MFAP3L,TMCC2,EFS,GAB1,DENND2A,SEPT9,GFER,GPD1,PRUNE2,SOX21,GPR45,SCIN,MEF2C,ADAM22,NEUROD1,NF1,NPTX1,LRRN3,NUDT11,SUGCT,RTN1,SCN2B,ASAP3,CCDC92,SOX2,WSCD1,PCDHGA10,DOCK9,SPX,TIAM1,PRMT8" Drug 1662_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASPHD1,ABHD6,CDC7,CDC42BPA,CDC14B,NCOA1,MTMR2,CACNA1D,SRSF11,TAOK2,CRY2,RIMS3,GIT2,DLG3,SIDT2,RBM12,PHF20L1,KAT8,FGFR3,ANKFY1,INPP5K,FERMT2,BTN2A1,HSF2,ITPKB,KCNH2,NAP1L2,NF1,NFYA,NRGN,SETD4,PIK3R1,POLG,SEC61A2,FERMT1,EMC1,RAP1GAP2,TACC1,TMPO,KCTD2,TNNT1,PLPPR2,LMF1,KLC2,TFIP11,WNK1,GDPD5" Drug 4291_UP PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADD2,PKP4,ZSCAN18,ASTN1,TAOK2,PLAA,CSF1R,CTNND2,RIMS3,MAML1,SPOCK3,DTNA,EDN1,SEMA3D,MBNL2,CEND1,PDLIM5,NSG1,GPD1,GPR22,RASSF8,KCND3,MDM4,AFF1,CTNNA3,SLCO1C1,NFIX,PDE2A,EPN1,PPARA,PRKAB2,PTAFR,ZSCAN32,RPS20,DZIP1,PKNOX2,SNCA,ZC3H13,MLC1,VAMP1,COBL,TMPO,CHST5,RUNDC3B,FLRT2,WNK1,KAT6A" Drug 6637_DN Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,AP2A2,MRTFA,KIF1A,CACNA1A,CACNB2,TAOK2,AKAP7,CSF1,PDE4DIP,EDRF1,EDIL3,TNK2,HSD17B14,PLEKHO1,MTSS1L,DENND4A,EZH1,F3,PDLIM5,PNMA2,FYN,GABRA2,ZNF44,GPD2,GPR37,GRM8,IDH3A,IL6ST,KCNMA1,KIF5C,MAPK8,CNNM2,PTN,ARHGEF10L,ZNF821,BCAN,ANKRD6,LIMS2,DDN,TROVE2,PDLIM2,TK2,WIPF1,EMSY,EVI5,PHTF2" Drug 2207_DN Betonicine [515-25-3]; Down 200; 25.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "RALGAPA1,ADRA1D,ALK,DOC2A,KCNAB2,GAS7,BCL7A,CDH8,COL9A2,SIPA1L1,PDE4DIP,GPRASP1,EEF1A2,EFNA3,RASGRP2,KCNMB2,POLL,GPR19,MAP4,SCAMP5,SLCO1C1,NOS1,OCRL,ODF2,PLP1,PTPA,MAPK3,CNNM2,RAB3IL1,RAP1GAP,RNASEL,C12orf49,TCP11L1,SEC14L1,FAM102A,ANKRD6,SLC11A1,ELMO2,IZUMO4,DBNDD2,RAP1GAP2,DDN,SYNE1,NSD1,ZMAT3,TRPS1,VSNL1" Drug 3720_DN Isosorbide dinitrate [87-33-2]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,ARID1A,C1QTNF3,ALDH7A1,SCARB1,AKAP7,AATK,DAPK3,RUSC2,PARD6A,ATN1,ELAVL3,PRELID3A,ZNF276,MSL3,POLL,ELOVL5,SCIN,IL6ST,VWA5A,MOBP,ZNF862,CNOT4,NTRK2,PDE3B,PFKFB2,MINDY2,PPP5C,CNNM2,ACSS3,RGS10,ZNF671,FOXRED2,BCAN,SOX15,IZUMO4,MAPK8IP3,MLC1,AP4E1,TIMP4,R3HDM1,TNS1,VIPR2,VLDLR,SCG2,MVB12B,GAN" Drug 5454_DN Tolfenamic acid [13710-19-5]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,ALCAM,PPFIA3,MARK4,SCAPER,MTMR2,QKI,HOMER3,CREM,DCAF8,RUSC2,EXOG,STX2,EZH1,FGF12,FHL1,DISC1,RAB30,MSL3,POLL,GRB10,ITPKB,KPNA5,MAP4,MATK,NDUFA5,NF1,NFYA,CNOT4,STRN3,MINDY2,PRPH,PTHLH,TMEM231,BTBD7,PHLDB1,PLCB1,SEMA4A,DNMBP,KIAA0930,TIAM1,KLC2,KCNK12,ZNF74,SPHK2,WNK1,GDPD5" Drug 6232_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ARID1A,ADCY6,APBB2,APOC1,PLA2G4C,ATM,BCL2L2,CHM,DAPK3,SGSM2,DNM1,ATN1,DTNA,MBNL2,ING4,ELAVL3,KIAA1109,FYB1,GABRA2,MALT1,GPR37,CACFD1,IGSF1,IL6ST,MATK,MOBP,NF1,NPPA,PRKAR1B,PTHLH,RGS3,RNASEL,FBXW7,SEMA6D,SH3BP2,ST6GAL1,HECW1,SPTAN1,ZBTB43,PHLDB1,MCF2L,TAL1,ARHGEF12,GPR161,CABIN1,TRPC1,NUP214" Drug 6058_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "KCNAB2,EPB41L5,ARRB1,SYNJ2,CAMK2G,ARHGEF1,SCARB1,SRSF11,HOMER3,ARMC8,CRY2,GREB1,DCAF8,TBC1D5,FBXL5,EFNA3,KAT8,FGFR3,GPR153,GLYR1,RAB30,TDRKH,HNMT,IL6ST,ADAM22,OGG1,PDE3B,NLE1,PRKAR1B,CNNM2,NEK11,IL17RB,FBXO11,WDR37,ZCCHC24,SPTAN1,TSPYL2,SPART,PHLDB1,VPS13A,PLCB1,TACC1,EXOC7,PSD3,REEP1,EPM2A,ST7" Drug 6707_DN Propofol [2078-54-8]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "OGT,PPFIA3,PDE8B,ALDH4A1,NRP2,ST3GAL5,ARHGEF7,MYRF,CANX,CDC42,FOXN3,TAOK2,RAB28,WHRN,ENTPD4,HP1BP3,CHRDL1,DLG3,FCF1,IRAK4,EPB41L1,COQ7,F3,KIAA1109,FGFR1,USP19,CNTRL,INPP5B,KIF5C,MAP4,SCAMP5,NF1,CNOT4,PDE4D,SH3TC2,FAT4,CCDC88A,TNIK,KDM4C,BEX1,TAB2,CAMTA2,SS18,GPR161,TPM2,ZKSCAN5,PHTF2" Drug 5728_DN Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "AP2A2,AK2,AMT,APC,APOC1,PPP4R4,CDC42,DNAJB5,SULT4A1,CRY2,EDRF1,SIDT2,EFNA3,EIF4G2,ING4,ANKMY1,TUBB4A,OGA,SRCAP,ZNF276,GLI2,TDRKH,KCNH2,MAPT,NDP,NF1,ODF2,CLDN11,PDE4A,NLE1,PTPA,MAPK7,RAB3IL1,GAL3ST4,KCTD17,MAP6D1,ZNF331,SH3BGR,FBXO11,ARHGAP26,DDN,THSD1,KAZN,TNS2,ZNF45,MAP3K12,DPF3" Drug 5343_UP Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "SRPX,APBA2,APC,ARRB1,CDK13,ATM,CFLAR,CA12,SCARB1,FAM189A2,FADS2,CSF1,ARHGEF10,SPOCK2,MFAP3L,CDON,DSCAM,OPTN,DLC1,KAT8,ZNF589,SEMA4D,TXNL4A,GLYR1,PCSK1N,SPACA9,INPP5B,KCNMA1,NFYA,PDE3B,NLE1,NKAIN1,RAD52,RGS12,SEC14L1,RPH3A,ERC1,SPART,TROVE2,INKA2,VPS13A,EXOC7,WSCD1,TRIM2,ZNF34,FAM155A,GDPD5" Drug 5018_DN Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABHD6,ARID1A,PLA2G6,C1QTNF3,BIN1,CDC42BPA,EP400,APP,CADM3,KSR1,GYG2,SLIT2,STOML1,AKAP7,ARHGEF10,PPP6R2,DCAF8,RASSF2,RIMS3,GIT2,PARD6A,EFNA3,EN2,DLC1,FGFR1,FGFR3,TMEM164,IQCG,GLYR1,POLL,STON1,DIPK1A,KCNN2,MAN2A2,ZNF862,PDE1C,PLEC,FAM120C,NKAIN1,CEP97,FAM184A,RGS12,KIF13A,ZCCHC24,TMOD1,FAM155A,MPPE1" Drug 7467_DN Methocarbamol [532-03-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "APC,CDK10,ST3GAL5,RAB28,FAM189A2,AKAP7,SLC4A7,DCAF8,HDAC4,GIT2,HP1BP3,FCF1,COQ7,BAIAP2,MALT1,GPR19,CLASRP,DIPK1A,NFYA,OGG1,PDE3B,STRN3,RETREG2,RAD51D,RALGDS,RGS10,FOXRED2,SBF1,ZNF365,EPN2,SLC6A8,SLC15A2,SOX3,MAPK8IP3,PHLDB1,ARHGEF9,COBL,MTCL1,TRIM2,KCTD2,ZMYND8,HIRA,ZNF184,MAP3K12,EMSY,MARCH8,SSPN" Drug 4250_DN 6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "TRMT9B,ADGRB2,KSR1,BAIAP3,MAP7,CACNA2D2,TAOK2,WHRN,CSF1R,ARHGEF10,ATN1,CNNM1,MTSS1L,TUBB4A,ST3GAL6,EFCAB2,SEPT9,RUNDC3A,GPR75,POLL,LPAR4,GRM1,KCNN1,LSS,AFF1,NOVA2,SLC11A2,ODF2,PLXNB1,PRKAR1B,PRPH,PTPRB,RGS4,RGS7,FRMPD1,TSNAXIP1,VAMP1,SZT2,TNS2,TPM2,ZMYND8,OSBP2,MICAL1,LMF1,SPHK2,NUP214,TIGD6" Drug 6615_UP Miconazole [22916-47-8]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADD1,BRINP2,BMP7,GYG2,LDLRAD4,CAPN3,TPP1,CP,CRY2,CHD5,PLPPR4,ABCC9,EDN3,HIPK3,ING4,CEND1,ZNF589,KIAA1109,FGF1,SIGLEC8,GCNT2,HNMT,HTR2A,KCND3,KCNN1,KIT,VWA5A,MGAT3,ADAM22,SAMD14,NEFM,PFKFB4,PMP2,RGS12,RYR1,SH3BP2,ASAP3,PPP4R3A,SNCA,KDM4C,SPTB,SYT11,FAM189A1,RUNDC3B,STMN4,SEMA3B,DPF3" Drug 1432_DN Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "KCNAB2,APC,APP,ATP2B1,N4BP2L1,SYNJ2,PLAA,SLC4A7,SOCS5,APPL1,CTH,ZEB2,DENND4A,ACSL4,SEC23B,SMC2,FAM49B,STAG2,TRAF3IP2,SPIN1,OS9,MAP4K5,IRAK3,IFI16,KTN1,AFF1,MYO5A,NAP1L1,NFE2L2,NFYA,NUCB2,SNX10,RETREG1,PLCD1,GSTCD,CLIP1,ATXN7,HSPA4L,DOCK10,FBXO11,RBM26,SPART,ZNF302,EPB41L3,STAU1,UBE3A,EVI5" Drug 2951_UP Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADRA1D,AGT,PLA2G6,AMPD3,BIN1,PPFIA4,APOC1,SCAPER,MYRF,CAST,ZFYVE9,COL9A3,ZNF337,TM9SF4,RIMS3,CELSR3,SORBS3,TNK2,MRNIP,FHL1,GRIK5,SCRG1,CNOT4,NRCAM,PLCD1,FSD1,RYR1,STUM,SNCA,TNIK,TSNAXIP1,IZUMO4,SPTAN1,PDLIM2,WWC1,SZT2,PCDHGA10,KCTD2,TNS1,FLRT1,VAV2,CLIP2,SLC13A3,TRIM9,SLC30A3,WNK1,KCNAB1" Drug 2488_DN Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "APBB2,CDK10,NMT2,BAG4,CREM,VCAN,CNNM1,LRRC23,NCALD,VPS26C,PTK2B,KIAA1109,TRMO,ZNF44,ZMYND11,WASF3,POLL,LILRA2,EML4,SPACA9,PADI2,SCAMP5,NEFH,NPR2,PDE4B,PLCD1,PTPRN2,RIPOR1,RAB3IL1,RAD52,MYH14,CARF,RASA3,SCG5,TMCC1,IZUMO4,KANK1,CAMSAP2,AP4E1,ICAM5,NSD2,XRCC4,ZNF24,SYNC,NT5M,UBE3B,ACTR3B" Drug 253_UP cox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADORA1,BIN1,ARNTL,DNAH17,NRP2,CAMK2A,ASIC3,TMEM59L,SH2B1,NCOR2,DYNC1I1,ING4,C3orf18,FGR,CYP46A1,GLI2,GNAL,GNAO1,GRM2,GRM8,FAM107A,IGF1,L1CAM,LAMA2,CTNNA3,FXYD6,PNMA3,PACSIN1,C19orf57,MAPK8,PYGM,RIPOR1,RAB3A,PNMA8A,FAM192A,FOXRED2,ABLIM3,CXXC4,SNCA,IZUMO4,SPTB,ZFR2,TEK,TNS1,SEZ6L,LMF1,NUP214" Drug 2755_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "KCNAB2,APOC1,CDK10,ARNTL,ATM,SLC4A4,ATP6V0A1,KIF1A,SYNJ2,RUNX1T1,CACNA2D2,PLEKHB1,DNAJB5,PPP6R2,EFNB3,EPB41L1,FOXG1,SEMA4D,TRAF3IP2,SEPT9,ALDH1L1,SRCAP,GNG4,ICA1,KCNN1,VWA5A,ZNF862,NOS1,NPTX1,NPTX2,PDE4A,PLXNB1,GON4L,C1orf54,SLC6A8,SIRT2,WDTC1,ARHGAP26,TSPYL2,ATP11A,DMXL2,TK2,TMOD1,WNK1,MAP3K12,DNALI1,GAN" Drug 7328_UP Nifurtimox [23256-30-6]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "PLA2G6,SEMA6A,CDK10,MARK4,SCAPER,BRSK2,SH2B1,SIPA1L1,GREB1,GIT2,EFNA3,EGFR,MTSS1L,EZH1,ATP8A1,ST3GAL6,FGFR1,IQCG,HBS1L,HNMT,KCNC1,KCND3,LMO1,MEIS2,MMP16,ADAM22,NFIX,POLG,RIPOR1,ZSCAN2,ATG16L1,RGS12,KCTD17,ZFHX4,SUGCT,SBF1,SHANK2,WDTC1,ST5,TMOD1,PARD3,RUNDC3B,ZNF23,ZNF74,UPF3A,PRDM2,SENP7" Drug 4162_DN Tobramycin [32986-56-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASPHD1,ASIC1,ADD3,MRTFA,AMT,PLA2G4C,CDK13,ASPH,CLCN3,SLC4A7,SNCAIP,MFAP3L,NR1D2,DTNA,FCF1,EFNA3,MBNL2,CAMSAP1,ZMYND11,GLYR1,HTATSF1,GNG4,GPD2,EML4,KCNK2,MDM4,KITLG,ADAM22,NF1,PRKAR1B,PTHLH,ZSCAN32,RAB3IL1,RGS10,PEX26,WDTC1,PLCB1,POPDC3,WASHC4,PSD3,AP4E1,PARD3,ZBTB38,REEP1,SYNC,FIP1L1,SSPN" Drug 3909_DN CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ACADM,ARID1A,APLP1,ARRB1,CFLAR,SYNJ2,CAMK2G,FADS2,USP6NL,LYPD1,DMPK,DNM2,DRD1,ATN1,EGR3,PLXNC1,HSD17B14,PLEKHO1,C1orf61,FAM49B,GCNT2,SRCAP,GLYR1,RAB30,ICA1,ITPKB,VWA5A,MAP2,MPP2,PIK3CD,RETREG1,PRKAR1B,PTHLH,RASA3,LIMCH1,NXT2,STX1A,PLCB1,KIAA1107,TNS2,SLC44A1,HEY1,PARD3,WNK1,GDPD5,PCBP4,PHTF2" Drug 6813_DN 6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "RALGAPA1,ARID1A,ALCAM,CDC42BPA,CFLAR,SYNJ2,SCAPER,GYG2,BTRC,ZFYVE9,TPP1,ENTPD4,SH2B1,CRY2,FAM169A,RIMS2,DCAF8,EXOG,ING4,LRRC23,FHL1,GLYR1,ARHGAP19,IL6ST,KCNH2,MAP4,TM6SF1,NOS1,PCBP3,NUMA1,STRN3,MAPK8,APTX,RAD52,RGS12,SLC25A36,CCDC25,ROM1,RPS6KA2,SEC14L1,ANKRD6,SLC9A5,MAPKBP1,CAMTA2,EXOC7,FIP1L1,ST7" Drug 6873_DN "H-89, Dihydrochloride; Down 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "BIN1,APBB2,CDK10,CDK13,ASPH,CFLAR,SYNJ2,CDH2,HOMER3,SLC4A8,CPS1,DZIP3,ZFYVE16,SGSM2,ABCC5,TENM1,ETV1,FGF13,FGFR1,FHL1,GLI2,POLL,NXPH3,KIFC3,SLC11A2,NUCB1,OCRL,PLEC,POU3F2,SAFB,SIRT2,SLC9A5,SLC14A1,BTBD7,SLC20A2,ZNF667,SMARCD3,POGZ,SYT1,KIAA0930,ARHGEF12,BHLHB9,FAM155A,LMF1,WIPF1,XRCC4,PHTF2" Drug 3936_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ACTN2,NME5,SEMA6A,KCNAB2,GAS7,APLP1,CDC14B,PLA2G4C,ASPH,BRINP2,ATP2A2,NECTIN3,CPS1,CSF1,CSF1R,DMPK,CDON,SLC12A6,EDN1,EFNB3,VPS13B,FHL1,IQCG,HBS1L,DISC1,JAK2,KIF5A,MAP4,NF1,PFKFB2,SERPINI1,RETREG1,STRN3,RGS10,ROM1,RPS6KA2,SEMA6D,SBF1,SH3BP2,DOCK10,FAM214B,MAPKBP1,IQCE,SATB2,TRPC1,VIPR2,EMSY" Drug 3637_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,ALCAM,DOC2A,AMPD3,BIN1,PPP4R4,ASPH,SYNJ1,BAIAP3,CA12,CACNA1A,FOXN3,LHX2,ZFYVE9,SH2B1,PDE4DIP,MFAP3L,ZNF589,FOXG1,C1orf61,FOXF2,PDLIM5,B4GALNT1,GCNT2,GPR19,GSN,MMP16,BCO1,NPTX2,PCDH9,EPN1,LRP12,PRKAR1B,RELN,ZDHHC14,RET,ZFHX4,KCNIP1,KDM4B,ZCCHC24,DOK5,DOCK9,TGFBR3,THRA,TNS1,ZFP37,ITM2C" Drug 2496_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABHD6,MTUS1,BIN1,FAM131A,APOC1,CDK10,BACH1,SYNJ2,TAOK2,ABCG1,RUBCN,EDRF1,ZNF337,DGKG,EFNA3,FAM13A,PLXNC1,EIF5,TUBD1,F5,PDLIM5,USP19,POLL,GRM1,TJAP1,MDM4,GIT1,OGG1,GPR85,RAB3A,RAB3IL1,ZNF821,GALNT10,EPN2,BTBD7,MAPK8IP3,ADGRL3,TCF4,TCF7L2,ICAM5,R3HDM1,VIPR2,CLIP2,XRCC4,ZNF225,NUP214,AAAS" Drug 4624_DN Ketoconazole [65277-42-1]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,MRTFA,STX16,ATP2B2,CACNA1I,CFAP410,CHN2,ABCG2,ARMC8,CABP1,HDAC9,BRINP1,SPOCK3,FCF1,MBNL2,SORBS3,TUBB4A,KIAA1109,CRCP,NASP,OPCML,PDE4D,PEX5,RAD51D,SH3TC2,FAT4,RGS4,RGS10,SCG5,SLC1A7,COA1,IFT122,DDN,THSD1,VAMP1,ARHGEF9,DNMBP,ADGRL3,WWC1,TCF7L2,ARHGEF12,AHCYL2,TK2,OSBP2,XRCC4,EVI5,EPM2A" Drug 2628_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "MTUS1,CDC42BPA,EPB41L5,BCAS1,APP,ADAM15,ST3GAL5,FUBP1,SPAG9,CLCN3,FAM189A2,CREM,SIPA1L1,FBXL5,G3BP2,EFNA3,EIF5,TNK2,EXTL2,F3,ANKFY1,CGREF1,SRCAP,MSL3,LIG4,NASP,NF1,SLC11A2,TMEM231,ZDHHC14,MYH14,CLIP1,AMBRA1,SS18,NXT2,DIP2A,PHLDB1,ASTN2,EXOC7,TBL1X,TIAM1,TMPO,RBFOX2,UBTF,MICAL1,XRCC4,RNF146" Drug 4779_DN Pyrimethamine [58-14-0]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "PLA2G6,BIN1,PPFIA3,ADAM15,CFLAR,CAMK2G,LHX2,HOMER3,SH2B1,CSNK1E,DCTN1,ZNF804A,SGSM2,ATN1,DTNA,EIF5,PDLIM5,FAM49B,KHDRBS3,SEPT9,ZNF276,PSRC1,ARHGAP19,ELOVL5,HNMT,MAP4,MITF,PDE4A,PLXNB1,PACSIN1,SAMD9,RGS3,KCTD17,EPN2,SMTN,ELMO2,BTBD7,KIF13A,CEP68,ARHGEF9,MCF2L,NSD1,TMEM121,TMOD1,CABIN1,HPS4,WIPF2" Drug 2390_DN "Glutethimide, para-amino [125-84-8]; Down 200; 17.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ALK,MRTFA,DOC2A,AMT,SYNJ2,CAPN3,MAP7,CCNT1,CD86,ZNF337,CTIF,KIAA0753,SIDT2,RBM12,SORBS3,ANKMY1,FCGRT,ZNF589,FHL1,OGA,FYB1,WASF3,ALDH1L1,SRCAP,SPIN1,LILRA2,ITPKB,NFYA,CNOT4,SSH1,PEX5,FAM184A,SH3BP2,KBTBD4,ARHGAP26,ZC4H2,TCF4,ARHGEF12,HIF3A,PIK3R5,ZMYND8,HIRA,XRCC4,ZNF32,UPF3A,PRDM2,PHTF2" Drug 7382_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "CDC42BPA,APP,SYNJ2,CA12,CCNT1,CLCN3,CLU,FADS2,BAG4,CSNK1E,PPP6R2,DLG3,DNM2,EDNRA,F8,AMOTL2,SCARA3,CINP,CAMKK2,GPR153,SYNPO,SMAD1,SLC11A2,SETD4,PAK3,PBX1,RC3H2,LRP12,MAPK7,SIDT1,RGS10,KIRREL1,AMBRA1,PEX26,ELMO2,TMCC1,FNBP1,NMNAT2,BEX1,ELOVL4,SUPT5H,EXOC7,TCF4,PARD3,UGT8,ZNF189,SH3GLB2" Drug 4776_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABHD6,ALDH4A1,BCL7A,CFLAR,CA12,ARHGAP33,AKAP12,GPRASP1,ZNF337,DAPK3,TUBD1,ANKMY1,WAC,DLC1,CAMSAP1,ZMYND11,ERAP1,TXNL4A,ITPKB,JAK2,KCNJ3,KIF2A,IPO5,MAP4,NCAM2,NF1,OCRL,PIK3R1,POLG,PPP2R5C,PRODH,CEP97,RXRA,ZNF331,FAM192A,SMTN,TACC1,SEMA4A,TCF7L2,DICER1,ZNF34,TPM1,VGF,LMF1,XRCC4,HPS4,MPPE1" Drug 5962_DN valinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADRB2,GAS7,ALDH7A1,KIF1A,SYNJ2,FOXN3,CHGB,TAOK2,PICK1,AKAP7,TCEAL2,CRMP1,CSF1R,IPCEF1,RIMS3,DRD1,HIPK3,CNNM1,MRNIP,FGFR1,CAMSAP1,GAB1,GNAL,GPD2,HLF,SHISAL1,DIPK1A,KCNMA1,ADAM22,NDP,EPN1,PRKAR1B,RAB3A,FBXW7,TCP11L1,SCN2A,DOCK10,CNKSR2,SOX10,SEMA4A,MCF2L,CRTC1,CHST8,TIAM1,OSBP2,TFIP11,KCNAB1" Drug 506_DN wortmannin; Down 200; 0.01uM; SKMEL5; HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "CDC42BPA,ARNTL,ALDH4A1,CAMK2G,SLC25A14,NIPBL,WHRN,COL9A3,CDC42BPB,CREB5,EDRF1,FEM1B,SUGP2,BSCL2,FAM198B,PCYOX1,TRMO,KHDRBS3,FYB1,GNAL,KCNJ5,MEF2C,ADAM22,NFYA,NLE1,PLEC,PPP2R5C,RAP1GAP,AP1AR,FOXRED2,ATXN2,SH3BP2,CHD9,ELMO2,SMARCD3,MAPKBP1,HECW1,EXOC7,ATP13A2,CHST8,TMPO,NSD2,NPDC1,ZNF184,EVI5,MPPE1,AAAS" Drug 2104_UP Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,MRTFA,ANK3,SEMA4G,ALDH7A1,KIF1A,SCAPER,SCARB1,CPS1,SDC3,CTIF,ELAVL2,PLEKHA1,EZH1,FGF1,FGFR1,FAM49B,SEPT9,LYVE1,TDRKH,CNTRL,ICA1,JAK2,GIT1,CNOT4,NOVA2,OPCML,PDE4D,POLG,TMEM231,RAB3IL1,GAL3ST4,SLA,SLC2A5,CCDC88A,ZKSCAN3,MYH15,COLGALT2,SYNE1,PSD3,CHST8,TPM1,SSBP2,HIRA,UBTF,LMF1,NT5M" Drug 2352_UP Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "NDRG2,AMT,KCNAB2,MARK4,CAMK2B,CAMK2G,SLC25A14,HIP1R,MAP7,TAOK2,IQCK,FEZ1,ARHGEF10,DAPK3,KIAA0753,COQ7,ST3GAL6,FOXG1,C1orf61,TRMO,PDLIM5,GABRA2,GAD2,NEU3,GRB10,ITGAM,VWA5A,MAPT,MDFI,MDM4,MPP2,CNNM2,RET,PLPPR3,MRAS,BTBD7,ZKSCAN3,SNAP25,DOK5,ZC4H2,VAMP1,EXOC7,PDLIM2,CRTC1,TMOD1,TPM2,HIRA" Drug 5671_UP Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "NDRG2,ADD2,KIDINS220,OSBPL1A,BIN1,APP,ATP2B3,CADM3,ADAM23,GYG2,JAM2,HOMER3,CPS1,HAPLN1,CST3,HDAC9,DBT,SGK2,HIPK3,EGFR,EPB41L1,DLC1,FHL1,FOXG1,DPYSL4,NSG1,NCKAP1,GAP43,ATP8A2,GRM8,TLX1,IGSF1,MATN3,PHKG1,SUGCT,PNMA8A,PPP1R9A,PREX2,SLC14A1,VAMP1,SYN2,OBSL1,DICER1,SPX,LAT2,SLC30A3,SEMA3B" Drug 1178_DN fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,ADORA2A,AP2A2,C1QTNF3,APC,PDXK,MARK4,CDC42,FOXN3,ARMC8,SEC31B,C2CD2,SPATA2,LPAR6,ENO2,ECSIT,ZNF589,FGFR1,CAMSAP1,CAMKK2,CACFD1,MAP4K5,SLC11A2,SETD4,PFKFB3,KCTD15,PLCB2,MBOAT7,PTPA,SAMD9,TMEM104,PTAFR,PTCH1,GTDC1,DZIP1,ARFGAP1,COA1,NCDN,FAM168A,TCF4,TCF7L2,NSD1,ZMAT3,CADM1,GORASP1,XRCC4,ZNF142" Drug 4381_DN PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "KIDINS220,AK2,SRPX,LTBP4,ALK,BIN1,PPP4R4,PDE8B,DNAH17,BRINP2,CADM3,SGCE,CACNA1I,CFAP410,CDC42,SOCS6,SLIT2,AKAP7,EDNRA,KIAA1109,FGFR3,KHDRBS3,TMEM8B,GRIK5,GRM1,MID1,ADAM22,NNAT,PDE4B,CDK14,POU3F2,PRKAR1B,PTHLH,ELOVL2,CCDC40,ZMAT4,KCTD17,RPS6KA2,SNCA,TSNAXIP1,DOCK9,HEY2,DAAM2,PARD3,UBE3A,VAV2,KAT6A" Drug 2531_DN Butamben [94-25-7]; Down 200; 20.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "NDRG2,ADRA1D,BIN1,DNAH17,CFLAR,CACNA1A,CAMK2G,CDH10,PLAA,HOMER3,SH2B1,PPP1R16B,PLXNC1,MTSS1L,F5,ST3GAL6,FCGRT,FHL1,FYB1,GRM8,MAP4,ZNF862,NF1,OLR1,PDE4B,ENPP2,NLE1,FAM120C,ZCWPW1,KHDRBS2,RGS10,ARHGEF10L,FOXRED2,FRMPD1,SLC1A7,BTBD7,TSNAXIP1,UNC5B,IQSEC2,TCF4,DMXL2,TCF7L2,THRA,RBFOX2,REEP1,FAM13C,ST7" Drug 3125_UP Nitrocaramiphen hydrochloride; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADD2,AP2A2,MTUS1,PLA2G6,AMPH,ADGRB3,MPDZ,BMP7,COL9A3,CRY2,CSF1,RIMS2,ZNF337,CTIF,TMCC2,HS3ST2,MAMLD1,SGK2,SRPK3,ETV1,F5,FGF12,WASF3,GPR22,SCRG1,KCNN1,CD200,ADAM22,NRCAM,OMG,CEP41,KLK6,PTPRN2,MARCH1,CLIP1,GALNT10,FAM102A,ASAP3,SLC1A3,PREX2,ADGRL3,CRTC1,ATP13A2,TPM1,RPRM,PLSCR4,ADAMTSL3" Drug 2125_DN Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADCY6,ADD1,ADGRF5,AMPD2,FAM131A,CDC14B,SEMA4G,ST3GAL5,MYRF,EPS15L1,SPATA2,CNNM1,SIDT2,IRAK4,F3,FGF1,BTN2A1,IL6ST,KIF2A,IPO5,PIK3R1,SLC25A23,MAPK7,CNNM2,SAMD9,GON4L,ZNF671,ATXN1,SH3BGR,SH3BP2,SLC1A7,RAB3GAP1,ZKSCAN3,SMARCA4,CAMTA2,COBL,EXOC7,EHBP1,TCF4,SATB2,TCF7L2,ZEB1,ARHGEF12,CABIN1,HIRA,XRCC4,AAAS" Drug 1146_DN "ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "APC,N4BP2L1,ADAM23,CDC42,SOCS6,SEC31B,RNF14,CSF1R,RHOBTB1,NR1D2,FCF1,ING4,CINP,GLS,GOLGB1,LILRA2,EML4,MUM1,HNMT,ICA1,VWA5A,TM6SF1,NFYA,ZNF426,PMS2,SAMD9,ZSCAN32,RNASEL,AMBRA1,ARHGEF40,ARFGAP1,SMARCC2,MAPKBP1,TMCC1,WDTC1,EMC1,PBLD,CAMTA2,ATP11A,EXOC7,TCF7L2,ARHGEF12,THBS4,THRA,ZNF32,EVI5,URM1" Drug 1495_UP Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "C1QTNF1,CDC42BPA,APBB2,APC,BCAS1,ARHGDIG,ASPH,CFLAR,ST3GAL5,SLC16A4,NEURL1,ARHGAP33,DNAJB5,HOMER3,ARMC8,AKAP5,DAPK3,SPOCK3,PHF20L1,TNK2,F3,DLC1,OGA,B4GALNT1,MBD1,MDM4,NELL2,NNAT,NUMA1,PLCD1,PACSIN1,MAPK8,PRODH,TRIM68,SFPQ,PPP4R3A,PKNOX2,SPTB,SPART,CHST8,ZKSCAN5,SPHK2,SCG2,UBE3B,RNF170,SSPN,SENP7" Drug 990_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "CACNB2,KYAT1,FOXN3,PICK1,CNTN1,ARHGEF10,PDE4DIP,SDC3,TRAPPC9,ATN1,HIPK3,EGR3,CDKL3,VPS26C,ZNF589,FGF12,FHL1,DISC1,AHDC1,GNG4,NR3C1,TJAP1,KCNH2,KCNN1,MIA2,LYRM9,NPR2,GRAMD1C,SAMD9,RGS10,RGS12,RNASEL,CARF,RPS20,SH3BP2,FUZ,CXXC4,WDTC1,SOX10,DOK5,TROVE2,MAPK8IP3,DIP2A,PLCB1,AHCYL2,SLC44A1,R3HDM1" Drug 6203_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,NDRG2,MTUS1,BIN1,SEMA4G,ALDH4A1,CFAP410,REPS2,CHM,TAOK2,CLCN4,CPS1,SIRPA,RUSC2,TRAPPC9,ST8SIA3,ELN,RASGRP2,ERCC2,FHL1,GABRA4,SRCAP,MAP4,N6AMT1,PDE4A,CDK14,PTPA,PRKCZ,WDR25,ZCWPW1,ZDHHC14,RGS10,ZFHX4,SLC1A3,SLC15A2,KDM4C,IQSEC2,ZC4H2,CUX2,TMOD1,KCTD2,TNNT1,TNS1,CDK20,TRIM9,NT5M,GDPD5" Drug 5021_DN Suloctidil [54063-56-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADD3,NME5,PPFIA3,RCBTB2,SRSF11,SOCS6,B4GALT6,LHX2,ZFYVE9,QKI,AKAP7,PDE4DIP,GREB1,TBC1D5,DBN1,EFNA3,MRNIP,COQ7,SCML2,FGFR3,SRCAP,USP19,GPD2,NR3C1,MUM1,PADI2,MMP16,NUMA1,LRP12,GON4L,PTHLH,GSTCD,LGR4,SHANK2,ZHX3,CLASP2,CEP68,IQCE,TCF7L2,RPGRIP1L,TMOD1,VGF,SF1,WNK1,MVB12B,SMIM8,PHTF2" Drug 442_DN oligomycin; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "BRAP,AMPD3,ARHGDIG,CADM3,DLGAP1,CHRNA4,JAM2,DNAJB5,CRMP1,ARHGEF4,CTNND2,KLHL3,DTNA,RUNDC3A,HPGDS,GPM6B,GRIK5,ELOVL5,SCIN,KCNF1,MAOB,SETD4,ODF2,PLCD1,MAPK8,MASP1,MTMR10,FAM184A,RET,FOXRED2,ATXN2,FUZ,ST6GAL1,ABLIM3,PKNOX2,KBTBD4,SLC15A2,SLN,EMC1,JMJD6,EXOC7,GPR161,CDH22,TMPRSS5,WIPF1,ZNF74,ST7" Drug 1346_UP Chlorogenic acid [327-97-9]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABAT,NDRG2,CDC42BPA,CDK10,ATP2A2,BCL7A,C5,CAMK2G,NFS1,SCARB1,QKI,NIPBL,BAG4,CPS1,GIT2,DLG4,DTNA,TOM1,PTK2B,ST3GAL6,FGFR1,EFCAB2,ERAP1,TXNL4A,GLYR1,KCNMB4,KCND3,NFYA,NPR2,PFKFB4,PIK3R1,CCSER2,PMS2,APTX,SBF1,SLC1A7,DHX30,BTBD7,ARFGAP1,KDM4B,BEX1,SRPK2,PLCB1,EXOC7,TBL1X,EHBP1,CHST8" Drug 2037_UP Lynestrenol [52-76-6]; Up 200; 14uM; HL60; HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ASIC1,APBB2,RASL11B,ADAM15,BMP7,MTMR3,CAST,RUNX1T1,CHRM4,KIAA1549L,ABCG2,DNAJB5,CRY2,AATK,CTH,C2CD2L,NR1D2,ATN1,DSCAM,TOM1,PLXNC1,ING4,RASGRP2,CAMSAP1,TRMO,CELF1,GPR12,HNMT,NEUROD2,NF1,FTO,PPP2R2B,RFX5,SH3BP2,FAM102A,SLC2A5,KBTBD4,ELMO2,ZC3H13,SPTB,LMO3,ST5,TBL1X,TMOD1,SEZ6L,CA14,MAP3K12" Drug 4699_UP Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "NME5,ASPH,ATP1A3,ADAM15,MPDZ,MTMR2,RUNX1T1,CDC42,QKI,RIMS2,EDRF1,GIT2,DBT,PARD6A,ATN1,RASGRP2,NCALD,RRAGB,FGF12,FGFR1,FHL1,GALC,GLYR1,GNAS,NUDT21,GRIK5,GSN,GSTM5,KCNJ3,KITLG,MID1,MSI1,STRN3,NKAIN1,PNMA8A,TCP11L1,SLC20A2,ZKSCAN3,UNC5B,SYN2,ZNF34,SSBP2,UCHL1,OSBP2,ZIC3,ZNF74,RNF146" Drug 1729_DN Iobenguane sulfate; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "APBB2,CDC14B,STX16,BARD1,BTK,SPAG9,PLAA,CLCN3,CLTB,PREPL,PPP6R2,RUBCN,DCAF8,KIAA0586,ZNF804A,G3BP2,MBNL2,EIF5,HTATSF1,PRRC2B,MAP4K5,HNMT,VWA5A,NF1,OGDH,KCTD15,TRHDE,PPP2R2B,ZSCAN32,ATXN2,SFPQ,EMC1,TROVE2,SS18,FCHO1,TAC3,MCF2L,AHCYL2,WBP2,TRPM2,SSBP2,HIRA,VIPR2,LAT2,TRIM9,PDSS2,EPM2A" Drug 2308_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "LTBP4,APBB2,APC,DGKD,PPP4R4,SLC4A4,SCAPER,HIP1R,RAB33A,CRMP1,EDRF1,FEM1B,EEF1D,EGFR,DMTN,EFS,IP6K2,GABRA2,NCKAP1,TXNL4A,MSL3,GSN,ARHGAP19,ELOVL5,TJAP1,KCNN1,NF1,SLC11A2,CDK14,PRKAR1B,ATG16L1,TCP11L1,CLIP1,ZNF821,FNDC3A,RPH3A,ZHX3,ZBTB43,VPS13A,TNS2,ACTR6,TRIO,HIRA,CADM1,LMF1,WIPF1,XRCC4" Drug 2119_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "KIDINS220,PPFIA3,ARRB2,ATM,CAMK2G,SPAG9,CLU,NIPBL,HOMER3,WHRN,CPS1,CSNK1E,TM9SF4,TBC1D5,SIRPA,DBT,SUGP2,TNK2,FAM49B,DENND2A,GLRB,PRRC2B,RNFT2,IFI16,IL6ST,L1CAM,MX1,CCSER2,TNPO2,GON4L,LGR4,AP1AR,ATXN7,SUPT20H,ITSN1,ASAP3,ZNF430,ZKSCAN3,CDK5RAP2,KDM4C,SS18,EXOC7,KIAA0930,ARHGEF12,CABIN1,HIRA,MPPE1" Drug 3517_DN Torsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABHD6,PPFIA3,MARK4,CFLAR,BMP7,SYNJ2,SLC4A7,ABI3BP,MICAL2,PDE4DIP,ARHGEF4,RUSC2,RCAN1,TSPAN5,RGS17,COQ7,BAIAP2,HBS1L,INPP5K,TXNL4A,MSL3,GPD2,HNMT,ADAM22,NPTX1,NRGN,SERPINE2,RETREG1,PLXNB1,FBXW7,RXRA,ASAP3,SMTN,SLC20A2,SLC22A4,WDTC1,FCHO1,ELOVL4,CEP68,VPS13A,ASTN2,TMEM121,AP4E1,ZMYND8,LMF1,WNK1,MAP3K12" Drug 1691_DN Triflupromazine hydrochloride [1098-60-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ABHD6,AP2A2,MRTFA,AMPD2,APAF1,CAPRIN2,NCOA1,ATM,ST3GAL5,C5,CCNT1,TAOK2,CLOCK,ABCG1,EDRF1,GIT2,FEM1B,SIDT2,IRAK4,EZH1,FER,HSF2,IL6ST,IPO5,MAPT,MIA2,NFYA,CCSER2,SLC25A23,MINDY2,PRKAR1B,GON4L,SNRK,TMEM231,ACSS3,FBXW7,NCDN,CEP68,TACC1,RPRM,UBTF,VAV2,WRN,TFIP11,EVI5,RNF170,LAS1L" Drug 3724_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "AMT,APOC1,ADGRB2,CANX,ARHGEF2,SOCS6,CHN2,B4GALT6,CHRNB2,CRY2,NCOR2,CTNND2,ARMCX2,PARD6A,DMPK,SIDT2,TUBD1,ATP8A1,FGF1,FGFR1,KCNMB4,TDRKH,CACFD1,CNOT4,PC,SERPINI1,PIK3CD,RETREG1,MAPK7,CNNM2,SAMD9,SUSD4,GAL3ST4,ROM1,IL17RB,TSNAXIP1,SPTAN1,DDN,SS18,MLC1,TNS2,TIAM1,TMPO,CABIN1,TNS1,VGF,GAN" Drug 4629_DN Droperidol [548-73-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "ADCY6,AP2A2,MTUS1,BIN1,AMT,PPFIA4,STX16,ADGRB2,CFAP410,PLEKHB1,ABCG2,CHD1L,RABGAP1L,ATN1,FCF1,MBNL2,DMTN,SEPT9,C1QL1,GPM6B,GRIK2,NR3C1,NUMA1,PIK3R1,GON4L,TMEM231,RAD52,SH3TC2,BSDC1,RGS4,RGS10,FOXRED2,ATXN7,ASAP3,SLA,SLC20A2,RBM34,WDTC1,TSNAXIP1,ADGRL3,SATB2,TNS1,NSD2,SF1,EMSY,EPM2A,SMIM8" Drug 3333_DN Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "AK2,APBA2,APC,BCAS1,CDK10,ATM,CFLAR,RAB29,SOCS6,CLU,FAM169A,CTNND2,TBC1D5,DAPK3,DBN1,KBTBD11,DNM2,KAT8,IQCG,PDLIM5,GNG4,RASSF8,DHX35,KCNH2,MIA2,MPP2,LYRM9,NF1,OCRL,MINDY2,PRKAR1B,TMEM231,RGS12,RPS6KA2,SAFB,SYBU,SMARCA4,SPTAN1,MAPK8IP3,PHLDB1,EXOC7,SMG6,TMOD1,ZKSCAN5,PLPPR2,VGF,EMSY" Drug 2052_UP Diazoxide [364-98-7]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "CDC42BPA,ATP1A3,CACNA1G,BTRC,B4GALT6,EDRF1,TUBD1,VPS26C,SCML2,FGF1,FGFR1,NOP56,GAD2,HPGDS,GNG4,GPM6B,GPR37,GRIK2,GRIK5,GRM1,INPP5B,MAP4,SCAMP5,ADAM22,NOS1,NUCB1,PROX1,SAMD9,RALGDS,KHDRBS2,GAL3ST4,SLC6A15,RGS4,TCP11L1,CSRNP3,ATXN1,IL17RB,SLC4A3,ARHGEF40,CEP68,COBL,ASTN2,EHBP1,SSBP2,TRIM9,MARCH8,NUP214" Drug 2298_DN Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "AP2A2,MRTFA,AMT,ANK3,SEMA7A,APBB2,APOC1,ARRB1,KIF1A,ADAM15,SCAPER,BTRC,MAP7,TPP1,NMT2,QKI,HOMER3,CREM,GIT2,KBTBD11,DTNA,LRRC23,FECH,GART,COPS8,NUDT21,EML4,NR3C1,MAP4K5,ATXN2L,HSD17B1,HSF2,INPP5B,JAK2,KIF5C,ZNF862,PRKAR1B,LRRC49,ZNF365,RCOR3,SS18,NXT2,PLCB1,TK2,PARD3,TRPC1,CLDND1" Drug 5723_DN Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "MTUS1,APLP1,APP,ATP2A2,ALDH7A1,CDK5R1,ARHGEF2,ASIC3,SULT4A1,VCAN,TOM1,STX2,ANKMY1,EZH1,FGF13,OGA,FYN,GNG4,GPER1,MAPT,MBD1,SCAMP5,ADAM22,ZNF862,NDP,NF1,CNOT4,NPR2,NUMA1,RETREG1,PEX5,PID1,GAL3ST4,TTLL7,IL17RB,FAM102A,AMBRA1,FBXO11,CCDC88A,SLC22A4,BEX1,TROVE2,ZNF34,METTL3,VGF,NSD2,PHTF2" Drug 6728_DN Betamethasone [378-44-9]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.65E-03 1.00E+00 1.07E-02 1.22E-01 47 196 "MRTFA,MARK4,ADAM23,MYRF,BTRC,ARHGEF1,CHN2,CRMP1,ARHGEF10,VCAN,RIMS3,EIF4G2,SORBS3,IRAK4,FYB1,FYN,LYVE1,LPAR4,GRK4,KCNN1,MAP4,NEUROD1,NOS1,NOVA1,SNTG1,PAK3,ZNF426,GRAMD1C,PTHLH,PTN,ZSCAN32,RALGDS,RGS10,MYH14,KIRREL1,RXRA,SH3BP2,DOCK10,WDTC1,LHPP,MAPK8IP3,TCF4,DOCK9,THRA,CABIN1,TRIO,PRDM2" Drug CID000004763 phenobarbital Stitch 1.66E-03 1.00E+00 1.08E-02 1.23E-01 78 360 "ABAT,ABR,AGT,APOC1,APOC2,ALDH7A1,CAPN3,CH25H,CPS1,ACY3,B3GAT3,ACOT8,AASDH,EGFR,ERBB4,PIPOX,F8,FECH,FOXM1,PNMA2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MSTN,CYP46A1,GGT7,GGT5,GJB1,HPGDS,GPT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,GSTM5,GSTT2,HAS2,ACOT7,INSM1,KCNH2,KCNQ3,NODAL,ABCB1,PLEC,PPARA,PRKCB,PRKCG,PKN2,PRKCZ,PTPRN,QDPR,PBRM1,GSTCD,RXRA,DDN,CLSTN2,APOM,ADHFE1,ZEB1,LEFTY2,GPR161" Drug CID000123817 dodecylphosphocholine Stitch 1.67E-03 1.00E+00 1.08E-02 1.23E-01 14 39 "AMPH,BIN1,APOC1,APOC2,BCL2L2,CACNA1B,CCKBR,MBP,NPY,PTHLH,PTH1R,TAC1,TACR1,TPM3" Drug CID006441213 LIGA20 Stitch 1.67E-03 1.00E+00 1.08E-02 1.23E-01 14 39 "SLC24A4,SLC24A2,CNTFR,B4GALNT1,NEU3,GFRA1,GFRA2,GRIK1,IL6ST,LIFR,NTRK2,NTRK3,SLC8A2,ZFP91" Drug CID000100208 Dolastatin 10 Stitch 1.67E-03 1.00E+00 1.08E-02 1.23E-01 14 39 "ABCG2,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,STMN1,MX1,ABCB1,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000001225 SKF 82958 Stitch 1.67E-03 1.00E+00 1.08E-02 1.23E-01 14 39 "ADORA2A,CAMK2B,CAMK2D,CHRM1,CNR1,DRD1,PPP1R1B,GRIA1,GRIN2C,GRIN2D,GRM1,PDYN,MAPK3,SYT1" Drug CID000005422 isotetrandrine Stitch 1.67E-03 1.00E+00 1.08E-02 1.23E-01 27 97 "KDM5D,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,CACNG7,CACNG2,SCARA3,LYVE1,KCNMB4,GPT2,HMGB1,LRRC25,KCNMA1,ABCB1,PKD1,RYR1,RYR3,SP4,RGL1" Drug 6319_UP Hexetidine [141-94-6]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "CACNG1,MAP7,LHX2,NRXN3,RAB26,CREB5,AATK,MICAL2,HDAC9,BRINP1,EDNRA,MBNL2,TNK2,SRPK3,FAM198B,DLC1,FYN,ZNF44,TRAF3IP2,INPP5K,ZNF276,GPM6B,GRK4,KCNK1,KIF5C,VWA5A,MT1M,NNAT,NTRK3,NUMA1,ODF2,RETREG1,POLG,SAMD9,PTPRE,RGS10,ATXN1,ELMO2,TROVE2,CEP68,SYT1,KIAA0930,GPR161,TIAM1,REEP1,KCNAB1" Drug 1663_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "APBB2,ARNTL,MARK4,NUMB,CFLAR,CACNA1I,BTRC,CAMK2G,B4GALT6,ZFYVE9,FADS2,ENTPD4,DBT,LYPD1,SMG7,MBNL2,KMT5B,SEMA4D,GHR,GLS,STON1,GPER1,GPR37,NR3C1,RNFT2,ARHGAP12,MMP16,ZNF862,PCDH9,PMP22,SIDT1,ZCWPW1,MYH14,WLS,SEC14L1,ZNF821,SH3BGR,ASAP3,SMTN,SLC6A8,ZCCHC24,FNBP1,TRIM2,CRTC1,BEX4,EMSY" Drug 2466_DN "Azathymine, 6 [932-53-6]; Down 200; 31.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "PKP4,APAF1,KCNAB2,APC,STX16,CFLAR,CCNT1,SRSF11,EPS15L1,CLCN3,HOMER3,ARMC8,SLC4A7,DBT,DTNA,FCF1,TUBD1,PDLIM5,CAMKK2,ZMYND11,INPP5K,SPIN1,GLYR1,HTATSF1,TJAP1,NF1,NFYA,CNOT4,NUMA1,PIK3CD,PMS2,PRKAB2,PKN2,GALNT10,SH3BP2,ZBTB43,TCF4,DICER1,SLC44A1,TMPO,KAT6B,TRPS1,FLRT2,PRDM2,NLRP3,SENP7" Drug 5085_DN Iodipamide [606-17-7]; Down 200; 3.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "MTUS1,ALDH7A1,ADGRB2,MPDZ,CACNA1A,MAP7,CBFA2T2,RCHY1,DAPK3,SMG7,CDON,EGFR,MBNL2,IRAK4,ETV1,VPS26C,ANKMY1,ZNF589,B4GALNT1,TMEM8B,IL6ST,JAK2,KCNN1,LIFR,MT1M,NF1,PC,STRN3,RAP1GAP,KIRREL1,PAQR6,AP1AR,CSRNP3,ZFP30,SLC14A1,ZNF415,TNIK,NXT2,TMPO,SSBP2,UGT8,VGF,WNT7A,ZNF74,EVI5,PHTF2" Drug 7078_UP Alsterpaullone; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "ASIC1,AP2A2,BIN1,APBA2,CASK,ASPH,NRP2,SYNJ2,KYAT1,LRBA,PLEKHB1,KIAA1549L,SEZ6L2,SIDT2,ERCC2,ACSL4,FGFR1,FHL1,ATP2C1,CELF1,CSPG5,GART,GNAL,DIDO1,MIA2,NCF2,NUCB1,POLG,PRPH,PTAFR,MCMBP,WLS,SFPQ,SCG5,SLC6A8,LIMCH1,BEX1,SEPT8,JMJD6,TCF4,AHCYL2,NPDC1,UPF3A,PRDM2,URM1,PCBP4" Drug 6555_UP Prostaglandin E1; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "APBB1,ADGRB2,SYNJ1,ST3GAL5,HAP1,MAP7,CBS,CCNT1,CREM,AKAP12,CSNK1E,CTH,GIT2,PITPNC1,G3BP2,EFNA3,MRNIP,ETV1,FYB1,INPP5K,GLYR1,GRM1,KCNN1,MAPT,MIA2,MX1,NF1,NTRK2,PC,PIK3R1,SMOX,PRKAR1B,CNNM2,SNRK,PTHLH,FBXW7,ZFP30,ASAP3,UNC5B,ARHGAP26,ZBTB43,MAPK8IP3,TBL1X,TCF4,MICAL1,NT5M" Drug 4437_DN 17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "C1QTNF3,LTBP4,MARK4,ADAM23,ADGRB2,BMPR1B,HIP1R,PLEKHB1,RAB26,COL9A2,HAPLN1,MICAL2,DLG3,ATN1,EDIL3,SIDT2,EFNA3,MRNIP,STX2,NCALD,SCARA3,HAS2,KLF12,MAPT,MIA2,NF1,ODF2,PFKFB4,PIK3R1,PLCB2,MAPK7,WDR25,PTPRH,RALGDS,KIRREL1,TMEM206,PPP4R3A,KDM4D,ARHGEF40,DDN,TROVE2,ASTN2,TMPO,ZBTB14,TRIM9,NT5M" Drug CID000004943 propofol Stitch 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "ASIC1,AK2,APOC2,HCN2,CACNA2D1,ASIC3,CHRM1,CHRNA4,CHRNB2,AK5,ARNT2,DMD,TRAPPC9,EDN1,AASS,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,STON1,GRIN2C,GRIN2D,IL1RAPL1,TNFAIP8L3,NBL1,NOS1,HCN1,CNTN3,PIK3C2A,PYGM,RYR1,RYR3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,ARX,SLC6A1,SCN3B" Drug 2190_DN Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "ADORA3,ADRA1D,PLA2G6,PPFIA4,APP,MPDZ,CAMK2G,LARGE1,DGKG,EFNA3,FAM13A,MRNIP,EIF1,ENO2,LRRC23,CDKL3,CD320,F5,FGFR1,FHL1,NBEA,CSPG5,WASF3,PADI2,MAP4,OLR1,PFKFB3,PLCD1,PLTP,POLR2F,PPP5C,RAB3A,RAB3IL1,GALNT10,SH3BP2,SLC2A5,LIMS2,SNCA,KDM4B,IZUMO4,DDN,KAZN,TGFBR3,R3HDM1,RBFOX2,ZKSCAN5" Drug 417_UP thioridazine hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "ADCYAP1R1,AGT,AMPD3,OGT,APOC1,CAMK2B,CANX,CDH18,CHRM4,KLHL3,DYNC1I1,DSCAM,SUGP2,EPHB1,FLNC,NSG2,CYP46A1,C1QL1,CNTRL,GRIK5,SOX21,HMGCR,MMP17,NPPA,NRGN,PHKG1,NLE1,PLEC,ATXN1,ATXN2,ZNF821,SH3BP2,FNDC3A,DZIP1,KBTBD4,ELMO2,LMO3,POPDC3,EXOC7,TNS1,PLPPR2,WIPF1,SLC13A3,SLC17A7,MVB12B,GAN" Drug 1225_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "APBB2,APP,MARCH3,MARK4,RIPK1,MTMR3,SLC4A7,DCAF8,KIAA0586,SORBS3,F3,FGF1,DPYSL4,POMT1,ERAP1,GBX2,KCNMB4,PCLO,NOVA1,NRGN,SETD4,PIK3R1,GPSM2,MINDY2,PTPA,PRPH,RIPOR1,ATG16L1,SEC61A2,MYH14,EPN2,SMTN,KBTBD4,SMARCC2,KDM4B,KDM3A,SYT11,NACC2,TK2,TSC2,TRIM9,ZNF189,MAP3K12,EVI5,WIPF2,FZD3" Drug 6498_UP Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.67E-03 1.00E+00 1.09E-02 1.23E-01 46 191 "AK2,C1QTNF1,CNTNAP1,APOC1,ATP1A3,GYG2,CACNB4,PLEKHB1,TPP1,SLC4A8,SNCAIP,GREB1,RCAN1,EGR3,C3orf18,FER,FGFR1,CAMSAP1,PDLIM5,TPPP3,GABRA2,GALC,PCDH17,RND1,TXNL4A,GPR75,GPR45,HMGCR,MBD1,PURG,PACSIN1,POU6F1,PPP5C,RGS3,WLS,ARC,TRIM2,DNAH7,SLC44A1,KCTD2,TRIO,TRPM2,HIRA,SLC30A3,EVI5,MVB12B" Drug CID000492400 NVP & EFV Stitch 1.67E-03 1.00E+00 1.09E-02 1.23E-01 32 121 "FGF17,NOG,TPP1,ABCG2,CREM,CSF2RA,HDAC9,ABCC5,EGFR,EN2,ERBB2,F8,FGF1,FGFR1,FGFR3,FLT1,FOLH1,GBX2,GRIN2C,GRIN2D,HPCA,HSP90AA1,IGF1,PDE4A,PDE4B,PDE4D,ABCB1,PIK3CD,PTCH1,RALGDS,VPS13A,ZIC2" Drug CID000010881 tropone Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "CBS,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,AFF1,PTK2,TUBB2A,TUBB1,TUBA1A" Drug CID000023678 "N,N'-ethylenebis(iodoacetamide" Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "DCC,TUBD1,ENO2,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000122777 AC1L3V8I Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "CA4,CBS,HEPH,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID011644425 CGP57380 Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "EIF4G3,CDC42,EIF4G2,KCNA2,MAPK3,MAPK9,MAPK10,MAPK12,STX1A,TSC2,ZBTB16,ST8SIA2" Drug CID000615942 NSC332598 Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "SLC4A7,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MX1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID000004429 AC1L1I5D Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "CCK,CCKBR,SULT4A1,BOC,SIRPA,DMTN,CSPG5,KCNJ3,OPRL1,PDYN,PENK,HPS4" Drug CID000032851 "3,4-dimethylhexane-2,5-dione" Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 12 31 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,NEFM,NEFH,CLSTN2,TUBB2A,TUBB1,TUBA1A" Drug CID000125748 anthglutin Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "KYAT1,GGT7,GGT5,SLC1A2,SLC1A3,SLC1A6,SLC1A7" Drug CID003964410 Mspg Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "GRIK1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug CID005311347 PD140548 Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "CALM1,CCK,CCKBR,KRIT1,B3GAT1,TAC1,TACR1" Drug CID000518955 TMBr-3 Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "MYH7B,TMOD2,TMOD1,TPM1,TPM2,TPM3,TPM4" Drug CID000125520 4-PIOL Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,SIRT2" Drug CID000093364 Ro 11-3128 Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GOPC" Drug CID000006367 acetyl chloride Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "ACLY,API5,PHF19,F3,NAP1L2,RNH1,CLSTN2" Drug CID000122783 8-hydroxycoumarin Stitch 1.68E-03 1.00E+00 1.09E-02 1.24E-01 7 13 "AK2,ATP2B1,ATP2B2,ATP2B3,FDFT1,NBL1,TAC1" Drug CID000000193 S-adenosyl-D-homocysteine Stitch 1.69E-03 1.00E+00 1.09E-02 1.24E-01 52 222 "AS3MT,ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,AMPD2,AMPD3,DPP10,CAMK2B,SPAG9,CBS,CCNH,CDO1,KMT2C,FADS2,CS,VCAN,CTH,DYRK1A,COQ7,ERCC2,DOT1L,GAA,AHCYL1,GATM,TCERG1,HNMT,KHK,MAT2A,N6AMT1,MTR,PCMT1,GPR85,PFKFB2,PFKFB3,PFKFB4,PFKP,POLR2F,PTPA,RAB3A,MYO18A,SHMT2,FBXO11,RPH3A,SUPT5H,TBL1X,NSD1,AHCYL2,METTL3,XRCC4,PRDM2" Drug CID000005680 A0666_sigma Stitch 1.69E-03 1.00E+00 1.09E-02 1.24E-01 18 56 "ADRA1B,SLC4A4,CACNA2D1,CAMK2B,CAMK2D,KRIT1,SLC4A7,CALCRL,KCND3,PMP2,PPP3CA,PPP3CC,PRKCB,PRKCG,KCNIP2,ABCC8,SYN2,CABIN1" Drug 3279_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.70E-03 1.00E+00 1.10E-02 1.25E-01 45 186 "MTUS1,ATM,STX16,ADAM15,MPDZ,CFLAR,SPAG9,KRIT1,CLCN3,SLC4A8,SOCS5,GREB1,TBC1D5,DBT,FCF1,SUGP2,IRAK4,ANKFY1,ZNF44,GHR,EML4,GPR37,IL6ST,ITPKB,KCNJ3,MMP16,NFYA,NUMA1,PIK3R1,SLC25A36,ZNF821,TRA2B,ARHGEF9,EXOC7,TBL1X,TCF7,TCF7L2,TRIM2,DICER1,BHLHB9,KAT6B,HIRA,WNK1,SNX27,FXR1" Drug 6831_UP Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.10E-02 1.25E-01 45 186 "MARK4,SYNJ1,SCAPER,HIP1R,FADS2,FAM149A,CABP1,ABI3BP,CPS1,CREM,EDRF1,MBNL2,USPL1,IGSF6,SCARA3,FYN,SEPT9,SRCAP,GNAS,GPD2,GRIN1,NXPH3,ICA1,IL6R,MDM4,MIA2,MN1,NOVA2,CDK18,SERPINI1,PRKAB2,KLHDC8A,RYR1,DOCK10,PEX26,TSNAXIP1,JMJD6,TBCEL,SMG6,EHBP1,WSCD1,UCHL1,ZFAND5,EVI5,FXR1" Drug 5072_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.10E-02 1.25E-01 45 186 "SLC12A5,ADRB2,AMPH,BIN1,SEMA7A,ASTN1,NRP2,HAPLN1,PDE4DIP,HDAC9,BRINP1,ST8SIA3,ELN,MTSS1L,FGFR1,SRCAP,GLI2,GPM6B,SPACA9,IRAK3,ICA1,MOBP,MSR1,NEUROD1,PDGFRA,PIK3CD,PTPRH,PTX3,RGS4,RGS10,RYR1,SLA,SLC1A7,KDM4B,ZC3H13,PHLDB1,SYN2,SYT1,ASTN2,KAZN,TBCEL,TNS1,TRIO,KCNAB1,AP3B2" Drug 1226_UP 17-AAG; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.10E-02 1.25E-01 45 186 "CDC42BPA,PKP4,GAS7,STX16,ALDH7A1,KIF1A,MPDZ,BID,CFLAR,C5,CBFA2T2,ZMYM4,FOXN3,ABI3BP,CRY2,CTH,EDRF1,GPRASP1,GIT2,TRAPPC9,EDN1,ELAVL3,PRELID3A,OGA,MSL3,GPER1,DIDO1,ITIH2,MMP16,GIT1,ADAM22,NACA,NFYA,OXTR,PTPRH,RAD52,C1orf54,GAL3ST4,RGS4,HSPA4L,PDZD2,TSNAXIP1,ZBTB43,SEMA3B,NUP214" Drug 5585_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.70E-03 1.00E+00 1.10E-02 1.25E-01 45 186 "OSBPL1A,BIN1,PRX,ST3GAL5,KYAT1,ZFYVE9,DNAJB5,NRG2,CTH,EDRF1,RUSC2,RCAN1,EDNRA,MBNL2,PLXNC1,EFS,CDKL3,OLFM1,OGA,GAD1,GLYR1,ICA1,CD200,NAP1L2,PDE1C,PMP2,C1orf54,TTLL7,SYNDIG1,HSPA4L,SH3BGR,CPEB3,DOCK10,ST6GAL1,PKNOX2,SLC9A5,SHANK2,COLGALT2,ARC,POPDC3,TACR1,WSCD1,DMXL2,ZEB1,VLDLR" Drug CID000127504 R 61837 Stitch 1.70E-03 1.00E+00 1.10E-02 1.25E-01 13 35 "KCNH8,CACNA1A,DCC,ELAVL4,FOXM1,TBR1,KCNA1,OGG1,ANLN,SLC1A3,SLC14A1,MESP1,ROBO3" Drug CID000129949 nitrobenzyl-DOTA Stitch 1.70E-03 1.00E+00 1.10E-02 1.25E-01 13 35 "TKTL1,SLC5A11,COG1,AASS,FGFR1,FGFR3,AKAP3,HTR2A,KCNH2,PTPRN2,ROBO2,SHANK2,BEST1" Drug ctd:C503753 Indolinone A CTD 1.70E-03 1.00E+00 1.10E-02 1.25E-01 13 35 "INA,DNM1,DPYSL2,DTNB,DNM1L,SH3GLB1,HNRNPK,IDH3A,MAPT,PDE4B,PACSIN1,MAPK3,SYN1" Drug CID010413188 Rp-8-CPT-cAMPS Stitch 1.70E-03 1.00E+00 1.10E-02 1.25E-01 13 35 "ADCYAP1R1,ADORA2A,ALDH7A1,HCN2,GCK,HCN1,PDCD2,PDE3A,PDE3B,PLIN1,PTPA,MLC1,VIPR2" Drug 6220_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.71E-03 1.00E+00 1.11E-02 1.26E-01 44 181 "APAF1,KRIT1,MICAL2,DCAF8,SACS,DNM2,EGR3,EIF5,PLEKHO1,TBC1D16,RACK1,FOXM1,CAMKK2,B4GALNT1,GHR,RNFT2,BRINP3,MBP,PDCD2,SSH1,PIK3R1,MAPKAP1,LRRC49,ZSCAN32,RFX5,ZDHHC4,RIC8B,AP1AR,SEC14L1,KBTBD4,CDK5RAP2,CDK19,TBL1X,ATP13A2,ZMAT3,TIAM1,SMUG1,LRP8,EVI5,MARCH8,UBE3B,PHTF2,ZNF248,NETO2" Drug 2675_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.71E-03 1.00E+00 1.11E-02 1.26E-01 44 181 "MTUS1,APAF1,APBB2,ATP1A2,ATP2B1,NRP2,CD86,LARGE1,EPS15L1,VCAN,PDE4DIP,EDRF1,RCAN1,HIPK3,MBNL2,EGR3,FER,PRKAG2,CAP2,ERAP1,GNAO1,STON1,GSN,IL6ST,TAGLN3,OLR1,P2RX7,ENPP2,SMOX,LRP12,CNNM2,RALGDS,SGK1,NTNG1,SHANK2,DOP1A,SPP1,ACSBG1,PLCB1,ANKRD28,DNMBP,DNAH7,AP4E1,ZNF34" Drug 3290_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.71E-03 1.00E+00 1.11E-02 1.26E-01 44 181 "APOC1,PDXK,BCL7A,CA12,LRRFIP1,CSNK1E,GREB1,SACS,TSPAN5,EGR3,TBC1D16,RACK1,CAMSAP1,SEMA4D,FAM49B,CAMKK2,MSL3,PRRC2B,GRB10,ITPKB,KCNH2,MAP4,MIA2,MMP16,NRCAM,PDCD2,PMP22,ELOVL2,RAB3A,RALGDS,ATG16L1,MAP6D1,LGR4,SPTAN1,CDK19,ATMIN,ZMAT3,TIAM1,CBX5,VGF,SLC38A1,EPM2A,FZD3,NETO2" Drug ctd:C101814 perfluoro-n-undecanoic acid CTD 1.72E-03 1.00E+00 1.11E-02 1.27E-01 86 404 "AGT,NR0B1,ALCAM,ANK2,DDO,RASL11B,CA4,CACNA1D,CH25H,CCK,LGI1,CDO1,CHGB,LHX2,ABCG2,C4orf33,TMEM184B,SLC35F1,CREM,FAM169A,RIPOR2,SACS,CHRDL1,EDN1,EDNRB,EEF1A2,SGK2,TMTC1,CERCAM,LRRC17,FABP7,OLFM1,AMOTL2,DKK3,ARPP21,GATM,GFRA1,GFRA2,PCDH17,CSDC2,GHR,GJB1,GPD1,TPPP,FICD,GUCY1A2,HAS2,HPS5,HMGCR,IGFBP1,IL11RA,ITIH2,KCNK1,LSAMP,MMP17,MT3,MX1,MYCN,MYH6,NBL1,NEFH,NELL2,NFE2L2,ENPP2,PPARA,RANBP3L,PTN,QDPR,S100B,SCN4B,SCP2,NTNG1,SLA,FAM81A,SLC8A1,SHANK2,SLCO1A2,SNCB,GLT8D1,TF,DCBLD1,TMEFF2,UCHL1,VIPR2,ETNPPL,WNK2" Drug CID000003822 ketanserin Stitch 1.73E-03 1.00E+00 1.12E-02 1.27E-01 34 131 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA3,ADRA1D,ADRA1B,ADRB2,AGT,CACNA2D1,CCK,CCKBR,CHRM1,PLCXD3,DRD1,DMTN,PLCD4,HRH3,TNFAIP8L3,HMGCR,HTR2A,HTR5A,KCNH2,PLCB2,PLCD1,SOX10,JMJD6,PLCB1,TAC1,TACR1,TF,TRH,NETO1" Drug 1345_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.73E-03 1.00E+00 1.12E-02 1.27E-01 43 176 "ADRB2,ARNTL,CDK13,ZBTB10,SLC4A4,RIPK1,CNOT8,TPP1,CX3CR1,ZFYVE16,DBN1,DTNA,FAM13A,ENO2,ANKFY1,ARFIP1,GLUL,ITGAM,LIG4,MXI1,PFKFB3,POLG,MINDY2,RET,TMEM156,SUPT20H,FBXO11,SLC2A5,SLC6A8,RAB3GAP1,KDM4B,KDM3A,KDM4C,NXT2,MAPK8IP3,ATP11A,TCF7L2,AHCYL2,TLR4,KAT6B,TNS1,REEP1,TFIP11" Drug 1393_UP Nocodazole [31430-18-9]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.73E-03 1.00E+00 1.12E-02 1.27E-01 43 176 "SHTN1,ARRB2,MARK4,ATP2B1,CFLAR,KRIT1,CD86,FOXN3,CHN2,CREM,MICAL2,PPP1R16B,DOCK4,PLEKHO1,PDLIM5,MALT1,MEF2C,PDE4B,PDE4D,SMOX,SMIM7,LRP12,MINDY2,PPM1B,PRKACB,PTK2,PTX3,CLIP1,ATXN1,ATXN7,SGK1,MAPKBP1,SAMSN1,EPB41L3,STX1A,PLCB1,TACC1,ANKRD12,TPM4,FLRT2,WIPF1,CLDND1,EVI5" Drug CID006332158 AC1O3MDH Stitch 1.74E-03 1.00E+00 1.12E-02 1.28E-01 28 102 "ADORA1,ADORA2A,ADORA3,ADRB2,AGT,NGB,CHRM1,EDN1,EDN3,EDNRA,EDNRB,B3GAT1,PPARGC1A,CRCP,GRIN2C,GRIN2D,CIT,HBA1,IGF1,NOS1,OXTR,POU6F1,RYR1,RYR3,TAC1,TAC3,TACR1,VIPR2" Drug 1598_UP Colchicine [64-86-8]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 1.75E-03 1.00E+00 1.13E-02 1.28E-01 42 171 "ARRB2,MARK4,ATP2B1,CAST,SPAG9,CD86,CREM,MICAL2,SIPA1L1,PPP1R16B,DOCK4,FAM13A,PLEKHO1,VPS26C,KIAA1109,CAP2,MALT1,PACSIN2,MBD1,GIT1,OLR1,PDE3B,PDE4B,SSH1,RETREG1,SMOX,BSDC1,ATXN1,ATXN7,SEC14L1,ARHGEF40,ELMO2,MAPKBP1,UHRF1BP1L,SAMSN1,EPB41L3,STX1A,PLCB1,ANKRD12,TPM4,WIPF1,CLDND1" Drug 2723_UP Cycloheximide [66-81-9]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.75E-03 1.00E+00 1.13E-02 1.28E-01 42 171 "BRAP,SPARCL1,DNAH17,SYNJ1,MAP7,CD86,CHRNA4,COL9A3,CREM,SIPA1L1,ST8SIA3,EGR3,TLR7,BAIAP2,ZNF44,TRAF3IP2,PCLO,SPACA9,KLF12,MEF2C,MGAT3,NOVA2,PDE4B,PMP2,PPP1R1A,SIDT1,PTX3,SUGCT,SCN2B,SH3BGR,RAB3GAP1,ATF7IP,ZNF415,DOP1A,SAMSN1,MAPK8IP3,SYT1,TGFBR3,UBE2H,LMF1,XRCC4,SCG2" Drug 2723_DN Cycloheximide [66-81-9]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.75E-03 1.00E+00 1.13E-02 1.28E-01 42 171 "AMT,KCNAB2,APBB2,ADAM23,CLCN4,ARHGEF10,MICAL2,ARHGAP32,ZNF337,TBC1D5,KBTBD11,RACK1,ZNF589,SEMA4D,CAMKK2,FYN,SEPT9,RAB40B,LILRA2,GPR22,GRB10,LSS,MAP4,PDCD2,TMEM231,RALGDS,FBXW7,RPS6KA2,LGR4,DZIP1,ZNF667,DDN,KANK1,ATP11A,KAZN,WWC1,TBL1X,ZMAT3,HIRA,NSD2,LRP8,NETO2" Drug CID000023930 manganese Stitch 1.75E-03 1.00E+00 1.13E-02 1.28E-01 155 791 "METAP1D,ADCY2,ADCY5,ADCY6,ADCY8,BRAP,ALAD,APOC1,APOC2,APP,PDXK,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,FUBP1,GYG2,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,NGB,CCK,KRIT1,RGN,CBFA2T2,ENTPD2,TIGD7,CACNA2D2,CHRM1,CHRNA4,B4GALT6,CHRNB2,CNOT8,ZFYVE9,COL4A5,GAL3ST1,CP,CPS1,ENTPD4,CSNK1E,CSNK1G3,DAPK3,B3GAT3,DNM1,DTNB,DYRK1A,AASDH,CACNG7,IRAK4,CALCRL,TUBD1,ENO2,DMTN,ERBB2,ERBB4,PIPOX,CACNG2,TUBA1B,PTK2B,TUBB3,TUBB4A,FDFT1,PPP1R1B,FECH,FGF1,POLR1B,ACTL6B,ATP2C1,FUT9,B3GAT1,GABBR1,GCNT2,TUBA8,GHR,TTBK1,GLUL,POLL,CNDP1,TUBA1C,GUCY1A2,GUCY1A1,GUCY1B1,GYG1,HBA1,IDH3A,IDH3B,IL12A,INPP1,TUBB2B,ITGA7,ITGAM,ITGAV,ITPKA,LAMA2,LIG4,MAP4,MBP,NBL1,NOS1,NPR2,SLC11A2,P2RY1,PC,PDE4B,PENK,PHKG1,PKD1,PKM,POLG,POLR2F,PTPA,PPP3CA,PPP3CC,PPP5C,PKN2,MAPK3,MAPK9,CNNM2,LAMA1,PTK2,PYGM,NUDT11,NEK11,ACER3,RYR1,RYR3,GALNT10,ASRGL1,FNDC3A,SLC11A1,SNCA,NMNAT2,ITPRID2,NUDT10,ATP11A,TF,ACTR6,CABIN1,TUBB2A,TUBB1,UGT8,WRN,TUBA1A,GAL3ST3,NUP214,MSRB3" Drug CID006442177 everolimus Stitch 1.75E-03 1.00E+00 1.13E-02 1.28E-01 35 136 "BRAP,ATM,PARD6A,EGFR,ERBB2,RRAGB,RPS6KC1,EVL,CAMKK2,PPARGC1A,IGF1,KCNA1,KCNH2,KIT,MBP,NPY,PDGFRA,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PTPA,PPP3CA,PPP3CC,RPS6KA2,TRERF1,MLST8,ALG1,CRTC1,CABIN1,PIK3R5,TSC2,UBTF,RICTOR,ZIC3" Drug CID000004402 AC1Q4Y39 Stitch 1.75E-03 1.00E+00 1.13E-02 1.29E-01 20 65 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ALDH7A1,CHRM1,SLC29A4,DRD1,F3,HRH3,KCNJ3,KCNJ5,PTPA,RGS4,EFHD1,MLC1" Drug ctd:D018967 Risperidone CTD 1.75E-03 1.00E+00 1.13E-02 1.29E-01 20 65 "CAMK2A,CHGA,CHGB,CHRM4,FADS2,ABCG2,DRD1,ERBB2,ERBB4,CAMKK2,HMGCR,HTR2A,KCNH2,MAOB,MAP2,ABCB1,PPP3CA,S100B,SNAP25,SLC17A6" Drug CID000012967 N-ethyl-N-nitrosourea Stitch 1.77E-03 1.00E+00 1.14E-02 1.30E-01 62 275 "APC,ARNTL,BLM,RUNX1T1,LRBA,RCBTB2,CHRNA4,QKI,HECTD1,AHCTF1,CRY2,TRIM69,RIMS3,CHRDL1,MED12,PHC2,EGFR,ENO2,COQ7,ERBB2,ERCC2,F8,FECH,B3GAT1,NRG3,GAA,ILDR2,GCK,GFAP,ATE1,RBPJ,ITPKB,AQP11,KITLG,MITF,MX1,MYO7A,NBL1,NELL1,NF1,PAH,PDE1B,ZNF655,PMS2,PTCH1,RASGRF1,FBXW7,SARS,SUPT20H,SMARCA4,SMARCD3,SOX10,DDN,ABCC8,SIRT1,ZFPM2,TSC2,CELF4,SMARCAD1,TUBA1A,PCDH15,IFT88" Drug ctd:D001565 Benzoates CTD 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "GPD1,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2" Drug CID006439129 AC1O5R1H Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "ACHE,BCHE,NPTX1,NPTX2,FXYD1,PTPA" Drug CID000194032 gamma-methyl-L-leucine Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "EDNRA,EDNRB,OPA1,PENK,EXOSC10,ARHGAP9" Drug CID000056205 difloxacin Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "NUMBL,ZMYND10,PDCD2,SLC14A1,ACSBG1,TRIO" Drug CID004369409 AC1NA019 Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "LHX2,CTH,IGSF6,MAT2A,RDX,RYR1" Drug CID000010692 copper gluconate Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "CP,GAA,HP,HPR,GSTCD,DDN" Drug CID000021803 chlorpyrifos-methyl Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "ACHE,BCHE,DMPK,DMTN,ATP8A2,CLDN11" Drug CID000407006 6-chloro-5H-purine Stitch 1.78E-03 1.00E+00 1.14E-02 1.30E-01 6 10 "ADORA1,ADORA3,EXOSC10,RNASE1,SALL1,SYNE1" Drug CID005192996 CID5192997 Stitch 1.79E-03 1.00E+00 1.15E-02 1.31E-01 25 88 "ALS2,NUMB,CABP1,NCALD,DKK3,GABRA1,GABRA2,GALC,DNER,CBX1,GRK4,WIF1,HPCA,KCNC1,KCND1,KCND2,KCND3,NPR2,PMP22,PTPA,MAPK3,KCNIP3,KCNIP2,KCNIP1,VSNL1" Drug CID000007045 Quinoxaline Stitch 1.83E-03 1.00E+00 1.17E-02 1.33E-01 17 52 "ADORA2A,ADORA3,CTH,F3,TNRC6A,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,SST,RGMB" Drug 6055_DN Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADRA1D,APBA2,SEMA4G,ALDH4A1,KSR1,CA4,CBFA2T2,SEPT7,HOMER3,CNTFR,CPS1,CSF1,SEC14L5,EXOG,CDON,HIPK3,EIF4G2,EN2,DLC1,FGF12,INPP5K,GRB10,SPACA9,GRIK5,GRM1,HLF,DHX35,KCNH2,VWA5A,SMAD1,MAP2,MGAT3,MPP2,MSI1,LRP12,PRKAR1B,RAB3IL1,RAD52,ZNF821,ANKRD6,FAM214B,VAMP1,VPS13A,TNS1,KCNK12,SEMA3B,KCNAB1" Drug 3924_DN Solasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "LTBP4,APLP1,DNAH17,MARK4,BRINP2,CFAP410,RAB28,CNTN1,CPS1,CSF1R,MFAP3L,CDON,DNM2,ATN1,DSCAM,EDN1,FCF1,STX2,ERBB2,FAM198B,PRKAG2,FHL1,GAD1,SRCAP,GLYR1,GLS,CACFD1,DHX35,IL6ST,ITIH2,KCNN2,CDK18,SERPINI1,PRKAR1B,FBXW7,SLN,COA1,LHPP,ATP10B,THSD1,AJAP1,VPS13A,PLCB1,PCDHA6,TRIO,KCNK12,PHTF2" Drug 4618_UP Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABAT,SLC4A4,NRP2,BTRC,CA8,SEPT7,RAB28,TMEM59L,FAM149A,NRG2,HAPLN1,CSF1,VCAN,CTNND2,SPOCK2,MFAP3L,EDNRA,APC2,ARPP21,HPGDS,GPM6A,GRM2,GRM8,KCNC1,KCNJ5,MAN2A2,MATN3,DDX25,LYRM9,MYL3,NEFM,NF1,OGG1,PDE4D,RETREG1,PPARA,SLC2A5,ZNF423,PHLDB1,SYN2,TBCEL,RALYL,VIPR2,REEP1,SLC30A4,CAMK1G,NUP214" Drug 3256_DN "Tocopherol (R,S) [10191-41-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AK2,ALCAM,GAS7,FAM131A,APOC1,ARRB1,ATM,SLC4A4,ADAM15,SYNJ2,PLEKHB1,TPP1,SLC4A7,NECTIN3,SH2B1,SOCS5,PPP6R2,DCAF4,DAPK3,ARMCX2,RABGAP1L,EGFR,IRAK4,ING4,OGA,GART,TXNL4A,SPACA9,GSN,ELOVL5,LYRM9,CNOT4,PEX5,RPS6KA2,EMID1,SH3BP2,FUZ,SIRT2,ELMO2,BTBD7,WDTC1,ATP11A,EHBP1,REEP1,FTSJ1,EMSY,EPM2A" Drug 5312_UP Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,ALCAM,APOC1,PPFIA3,ASPH,KIF1A,CFLAR,ADGRG1,FOXN3,TAOK2,VAX2,QKI,FEZ1,PDE4DIP,GREB1,EGFR,ABI2,EGR3,COQ7,B4GALNT1,GFER,POLL,IL6R,KHK,LSS,MAPT,ADAM22,NFYA,OGG1,RAB3A,RAB3IL1,RET,TCP11L1,SLC1A7,COA1,KDM4B,PHLDB1,DNMBP,TCF7,TRIM2,KAT6B,CDK20,VIPR2,GDPD5,HPS4,NAV2,ZNF248" Drug 2844_DN Terconazole [67915-31-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG3,CDC14B,MARK4,NUMB,EIF4G3,SYNJ2,BTRC,CAMK2G,PLEKHB1,TAOK2,QKI,ENTPD4,CTNND1,GIT2,SGSM2,DNM2,FEM1B,SUGP2,EIF5,ENO2,F3,KAT8,FHL1,ERAP1,GART,GLYR1,GPD2,KCNJ3,IPO5,MAP4,GIT1,CNOT4,SETD4,NKAIN1,BSDC1,RIC8B,TCP11L1,SIRT2,KDM4C,ERC1,THSD1,FAM168A,EXOC7,FRYL,RBFOX2,WRN,PHTF2" Drug 2941_DN 3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,NDRG2,MRTFA,KIF1A,FUBP1,OSGIN2,CFAP410,KRIT1,SLC16A4,FOXN3,SOCS6,LHX2,ZFYVE9,CLCN4,DGKG,B3GAT3,RABGAP1L,SIDT2,RASGRP2,SCML2,PADI2,MAP4,MEF2C,MX1,PDE4A,CCSER2,PLCL1,STRN3,ZSCAN32,RAD52,ZNF493,ATXN2,GALNT10,ANKRD6,KBTBD4,ZNF667,ZCCHC24,KDM4C,TSPYL2,SEPT8,TCF7L2,PSD3,AP4E1,ZMYND8,FLRT2,MAP3K12,FZD3" Drug 7212_UP Delsoline [509-18-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,KIDINS220,AK2,AMH,AQP4,BAIAP3,BTRC,CHM,CABP1,SDC3,INTS1,SRGAP3,EDIL3,OPTN,EFNA3,HSD17B14,MTSS1L,ATP2C1,OGA,DKK3,SRCAP,GPD2,PRDM5,GUCY1A2,KCNQ3,MITF,MMP16,NFYA,CNOT4,PHKG1,LRRN3,MAPK7,KHDRBS2,TCP11L1,SLC11A1,ZCCHC24,IQSEC2,SS18,PHLDB1,PLCB1,EXOC7,ARHGEF12,TF,DAAM2,PIK3R5,PRMT8,SYNC" Drug 5536_DN Scoulerine [6451-73-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SLC12A5,AP2A2,APC,EPB41L5,CDK5R1,NMT2,NECTIN3,CSNK1E,PDE4DIP,DCAF8,ZNF337,GIT2,MFAP3L,RABGAP1L,DPH1,EFNA3,EGFR,IRAK4,EPB41L1,ANKMY1,SEMA4D,TRMO,PRELID3A,TRAF3IP2,NCKAP1,SPACA9,RNFT2,VWA5A,MIA2,GIT1,LRP12,TNPO2,POLG,MAPK8,RGS12,SBF1,PEX26,PPP4R3A,SLC22A4,RCOR3,SPART,FAM168A,SEMA4A,EXOC7,SLC44A1,PIK3R5,CLDND1" Drug 2163_UP "(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SYN3,NDRG2,APBB2,DDO,APP,CDK10,SEMA4G,CADM3,CAST,MAP7,CRMP1,SIPA1L1,PPP1R16B,SV2B,SIDT2,SORBS3,VPS13B,KIAA1109,PDLIM5,FYB1,GAP43,GSN,ITIH2,KIFC3,MAP4,CD200,ZNF862,NEUROD1,NPR2,NTRK2,PURG,SUSD4,RFX2,RGS10,TCP11L1,MAP6D1,STUM,SLC1A3,PKNOX2,SNAP25,LHPP,AJAP1,FAM168A,CAMSAP2,SLC35G2,VSNL1,KCNAB1" Drug 1208_DN "estradiol, USP; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "C1QTNF1,BIN1,APAF1,KCNAB2,PPFIA3,BCHE,SCAPER,ABI3BP,APPL1,OPTN,MBNL2,SORBS3,C3orf18,EML1,F3,ATP8A1,FGFR1,GPR19,IL6R,MATN3,SLC11A2,CDK14,PIK3R1,STRN3,RETREG2,FSD1,PRPH,SIDT1,RIPOR1,RAD52,RALGDS,NUDT11,MCMBP,ITSN1,SLC20A2,SNCA,SPTAN1,SEPT8,STX1A,SYT11,WSCD1,ZNF34,METTL3,SMUG1,HIRA,ZNF189,UBE3B" Drug 6094_DN Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,SEMA6A,SRPX,MRTFA,APBB2,PPFIA3,SLC4A4,CACNA1I,CACNA1A,CLU,FAM189A2,QKI,CSF1R,FEZ1,PDE4DIP,RIMS3,DAPK3,RUSC2,RCAN1,HIPK3,EGFR,ING4,ZNF276,KCNMA1,ADAM22,NF1,SLC11A2,NRGN,PPP2R5C,PTN,RAB3IL1,RGS10,PAQR6,ZNF821,SLC1A7,SMARCD3,KDM4C,ZC3H13,IQSEC2,ST5,NCDN,MAPK8IP3,VPS13A,SYN2,KIAA0930,ZMYND8,VLDLR" Drug 2309_DN Tropicamide [1508-75-4]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AK2,SEMA7A,BCL7A,NMT2,QKI,ENTPD4,EDRF1,RCAN1,OPTN,SORBS3,COQ7,F3,GPR153,ERAP1,TXNL4A,GRIK5,CACFD1,GRM1,GSN,HNMT,KCNN2,VWA5A,MAP4,TM6SF1,LYRM9,ZNF862,NTRK2,STRN3,MINDY2,PPP5C,FAM184A,FBXW7,ZNF365,KDM4B,WDTC1,PLCB1,TCF7L2,TK2,TMOD1,MICAL1,LMF1,ZNF24,GDPD5,HPS4,MVB12B,EPM2A,RNF170" Drug 444_DN clofibrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARHGDIG,ARRB1,C5,DLGAP1,CHRNA4,JAM2,DNAJB5,PICK1,CPS1,CSNK1E,SEC14L5,KLHL3,RCAN1,DTNA,ECM2,FEM1B,NCALD,FGFR1,IQCG,GJB1,RUNDC3A,HPGDS,GPM6B,GRM1,SOX21,MEIS1,MPP2,ADAM22,NOVA1,PRODH,NDUFS7,MTMR10,ZSCAN32,RGS3,ABLIM3,SLC9A5,KBTBD4,POGZ,EXOC7,EHBP1,CDH22,METTL3,TMPRSS5,WIPF1,ZNF74,STMN4,NUP214" Drug 2427_UP Butoconazole nitrate [32872-77-1]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SYN3,NDRG3,ADORA1,FAM131A,MPDZ,KSR1,SGCE,CACNA2D2,ZFYVE9,CLCN4,DZIP3,TM9SF4,EDNRA,EIF1,FGFR1,INPP5K,NEU3,ALDH1L1,PTGDR2,HTR5A,IL6ST,MYO6,NTRK2,PDE2A,PGAM2,PLP1,MTRF1L,PPARA,CNNM2,WDR25,RFX3,ZFHX4,MAP6D1,SEC14L1,SH3BGR,RPH3A,PREX2,CXXC4,ATP10B,MAPK8IP3,SEPT8,MTCL1,TAL1,RPGRIP1L,PCDHGB6,PCDHGA10,SLC17A7" Drug 7253_UP Methylatropine nitrate [52-88-0]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "RALGAPA1,ASIC1,AMPD3,KCNAB2,DNAH17,MYRF,NEURL1,CDH10,NRXN3,ZFYVE9,WHRN,VCAN,PDE4DIP,CTNND2,GIT2,CDON,ANKMY1,ZNF589,FYB1,ERAP1,GLS,POLL,CNTRL,ITGA7,KCNF1,KCNN1,MATN3,MBD1,SCAMP5,NUMA1,PDGFRA,STRN3,GON4L,SUPT20H,SLC1A3,SLC6A9,KDM4C,TROVE2,PLCB1,SYT1,DOCK9,TK2,TNS1,WNT7A,ZNF711,TFIP11,KAT6A" Drug 5939_DN PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SYT13,BIN1,CDK13,ATP2A2,ADAM15,ADGRB2,NRP2,CALB2,SYNGR3,NRXN3,AKAP7,PDE4DIP,TBC1D5,MFAP3L,SPOCK3,EPHA5,ETV1,ZMYND11,MAP4K5,RASSF8,TJAP1,KCNJ5,KCNN1,GPR85,CCSER2,RETREG1,PLEC,POLG,PTN,MYH14,FBXW7,SEMA6D,SAMSN1,PLCB1,TIAM1,TMOD1,CABIN1,ZMYND8,VAV2,VGF,NSD2,CLDND1,ZNF74,PRDM2,PARP6,EPM2A,GJC2" Drug 7491_UP CP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "CNTNAP1,APBB2,CDC14B,C5,MAP7,CBFA2T2,ASIC3,QKI,RAB26,AKAP7,ARMC8,CTH,ARNT2,PLEKHO1,DMTN,CDKL3,BAIAP2,TRMO,CINP,CGREF1,DENND2A,GART,MSL3,PDGFRA,KCTD15,CDIP1,SAMD9,PTHLH,PEX5,TMEM231,FAM184A,GSTCD,SBF1,SLC20A2,WDTC1,KDM4C,SS18,SZT2,HIRA,UBE2H,UGT8,WIPF1,TRIM9,MAP3K12,EMSY,ST7,UBE3B" Drug 3456_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABR,ACTN1,SLC12A5,AP1B1,APBB2,CDK13,BMP7,SYNGR3,RAB28,CSNK1E,FAM169A,PPP6R2,TM9SF4,B3GAT3,MFAP3L,LYPD1,MED12,EIF4G2,EIF5,EPB41L1,LRRC23,ZNF589,FAM49B,GCNT2,SRCAP,GLS,GRB10,INPP5B,LSS,MPP2,GIT1,NF1,OXTR,PLEC,FSD1,APTX,RIPOR1,ZCWPW1,NEK11,CLIP1,SCMH1,TSPYL2,SPART,FAM168A,TMOD1,TRPC1,PLPPR2" Drug 348_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADCY2,C1QTNF1,AMT,ANK2,CACNA1A,PTBP2,CDO1,CNOT8,ECE2,CTIF,JAKMIP2,E2F5,IRAK4,TNK2,ETV1,CEND1,F8,TUBB4A,ZNF589,FGFR1,BAIAP2,C1orf61,FAM49B,FYN,HBS1L,GJB1,RUNDC3A,RAPGEF1,GRIA4,KCND3,NOS1,OMG,NLE1,PPP3CB,PKN2,SH3GL3,KIF16B,KBTBD4,CDK5RAP2,ARHGAP26,KLHL7,AGTPBP1,TRIM2,TMEM121,SEZ6L,MPPE1,GAN" Drug 3007_DN Indoprofen [31842-01-0]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABAT,PLA2G6,BCAR3,CFLAR,CACNA1A,CAMK2G,CHRNA4,ZFYVE9,CLCN4,DNAJB5,NRG2,PDE4DIP,RUBCN,BRINP1,FAM13A,ABI2,AASS,C3orf18,DLC1,ZNF589,GABRA2,SEPT9,ADAM28,LILRA2,GRM7,IL11RA,MGAT3,ZNF862,ODF2,OLR1,MAPK8,RAB3A,ZDHHC14,ZNF671,MAP6D1,CLIP1,FBXO11,ZNF415,DDN,DMXL2,TCF7L2,PSD3,TRO,OSBP2,FLRT1,MAP3K12,SEMA3B" Drug 583_DN HNMPA-(AM)3; Down 200; 5uM; PC3; HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABR,ADD3,CDC14B,ADGRG1,CLTB,NIPBL,HAPLN1,FEZ2,CNTNAP2,HP1BP3,FEM1B,RBM12,EGFR,ING4,MRNIP,RGS17,BSCL2,C3orf18,EN2,FGF1,SCARA3,SEC23B,GAB1,SEPT9,GLS,PRRC2B,SLC2A6,MAN1B1,HMX1,KCNH2,KCNJ5,MBD1,MBP,NOS1,C19orf57,QDPR,RALGDS,GSTCD,CSRNP3,TNIK,EPB41L3,TBL1X,TUB,NPDC1,ZNF23,SLC17A7,AAAS" Drug 5201_DN "aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADCY6,AP2A2,ARRB2,BRINP2,CFLAR,AP4M1,SLIT2,DTNA,SUGP2,EGFR,SORBS3,PLEKHO1,EPB41L1,FGFR1,BAIAP2,ANKFY1,OGA,GALC,GNG4,GPD2,TDRKH,ATXN2L,INPP5B,KCNF1,KIF5C,MDM4,ADAM22,NF1,NFYA,SLC11A2,MAPK7,KLK6,SYTL2,RIPOR1,RGS10,SH3BP2,ZHX3,ZSWIM8,EMC1,TROVE2,PSD3,PCDHA6,AP4E1,TK2,CDK20,VGF,SF1" Drug 4266_DN Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASPH,KRIT1,SRSF11,ZFYVE9,CREM,PDE4DIP,SMG7,SPOCK3,EFNA3,ING4,ATP2C1,FYN,TRAF3IP2,CRCP,SPIN1,PCLO,KIF3A,AGFG1,IL6ST,KIF5C,MAP4,TM6SF1,NFIX,CNOT4,PAK3,PDE1C,STRN3,PTN,RAD51D,SLC25A36,FBXO11,PBLD,THSD1,ZC3H4,KAZN,WWC1,TCF4,TRIM2,ARHGEF12,DICER1,TMPO,SF1,TFIP11,WNK1,EVI5,MPPE1,FXR1" Drug 7169_UP Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,AK2,BIN1,ALDH4A1,CADM3,ARHGEF7,SCAPER,ARHGEF2,NRXN1,FAM189A2,HAPLN1,SOCS5,PDE4DIP,GIT2,LYPD1,RABGAP1L,CDON,RCAN1,DTNA,SGK2,MBNL2,CDKL3,BAIAP2,FHL1,SYT17,GNG4,NR3C1,GRM8,HPCA,KCNN1,LMO2,LSS,LRRN3,MAPK7,PRPH,SAMD9,FAM120C,RIPOR1,ZDHHC14,RPS6KA2,FRMPD1,SLC11A1,EMC1,TTBK2,VPS13A,TPD52,SSPN" Drug 1389_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,ADORA3,OGT,APBA2,CDC14B,CFLAR,CD86,SEPT7,ADGRG1,EPS15L1,SLC24A2,CNTN1,SPOCK2,MED24,DSCAM,SRPK3,CDKL3,EZH1,MPP6,SPIN1,GLYR1,INPP5B,MAN2A2,MAP4,TAGLN3,NPY,NPPA,ODF2,CDK14,CNNM2,DEF8,RNASEL,NEK11,SH3BP2,CCDC88A,ZHX3,PEG10,ST5,MAPK8IP3,PHF24,TMPO,R3HDM1,KAT6B,CHST5,LAT2,SLC17A7,CAMK1G" Drug 3400_UP 2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "FZD9,C1QTNF1,KCNAB2,CACNA1I,CAMK2B,RUNX1T1,CDH8,RAB33A,SULT4A1,WHRN,SDC3,RASSF2,ING4,ELAVL3,TUBB4A,DLC1,FGR,FHL1,FOXG1,TMEM8B,GPER1,GRM1,HRH3,HLF,KCNMA1,LIFR,AFDN,ADAM22,TAGLN3,MX1,MYCN,CLDN11,CAMKV,PTCH1,FAM120C,ZDHHC14,ZMAT4,S100B,BCAN,CXXC4,RIMS1,CLSTN2,MLC1,ARC,EXOC7,SYNE1,EPM2A" Drug 2233_DN Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AMT,APBA2,APOC1,CFLAR,GYG2,CACNA1A,SYNGR3,ARHGAP33,FAM189A2,SIPA1L1,SEC14L5,RIMS3,CTIF,TMCC2,CDON,EDNRA,ANKMY1,SCML2,CAMSAP1,FHL1,FOXG1,IQCG,GNG4,CACFD1,ICA1,MIA2,MMP16,MYO7A,CDK18,PDE3B,PRKAR1B,PRODH,PTHLH,RGS10,RXRA,PREX2,STX1A,VPS13A,PCDHA6,TRPC1,FAM155A,FLRT2,VLDLR,WIPF1,WNK1,KCNAB1,PHTF2" Drug 4673_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARID1A,ALAD,PPFIA4,APBB2,ARRB2,ADAM23,CACNA1G,CAMK2B,SYNGR3,AKAP7,SH2B1,ARHGEF10,VCAN,SGSM2,DTNA,EFNA3,CDKL3,ST3GAL6,AFF2,FYB1,GABRA2,ZNF44,GNG3,GPR37,KIF5C,MAPT,AFF1,OPCML,MAPK7,SAMD9,ELOVL2,RGS10,SUGCT,ZNF671,MCMBP,NLGN1,ARHGAP26,SPTAN1,DDN,LHPP,TCF7L2,THRA,TIAM1,TNS1,ZMYND8,WIPF1,TIGD6" Drug 5887_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "PPP4R4,ARNTL,CDK13,BMP7,CACNA1I,CACNA1G,CACNA1A,CAMK2B,CBFA2T2,NEURL1,AP4M1,DNAJB5,HAPLN1,PDE4DIP,CTNND2,MAGI2,SMG7,EGFR,MBNL2,RGS17,FOXG1,SEPT9,MSL3,LPAR4,GRIK5,SCIN,INPP5B,KIT,MATN3,MX1,PTN,ACSS3,RAD52,SH3TC2,RGS12,KCTD17,NEK11,FBXW7,EMID1,ASAP3,TSNAXIP1,COBL,ZFPM2,VIPR2,WIPF1,WNT7A,KCNAB1" Drug 1941_DN Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "FAM131A,ST3GAL5,FUBP1,CARS,ARHGEF2,CDH2,ADGRG1,SLC4A7,PPP6R2,TM9SF4,SIRPA,DCTN1,SGSM2,DTNA,SORBS3,C3orf18,EPB41L2,COQ7,ERBB2,TMEM164,SEPT9,MAN1B1,IL6ST,SMAD1,MITF,MX1,PAK3,MBOAT7,TNPO2,MED1,CNNM2,PTN,RALGDS,ATXN7,SHANK2,CDK19,POGZ,NCDN,VAMP1,TBL1X,TRIM2,OBSL1,SPX,HIRA,ZNF142,LRP8,MPPE1" Drug 1322_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "MAP4K3,GAS7,CDK13,N4BP2L1,CFLAR,RAB28,TM9SF4,TBC1D5,GSDME,SUGP2,ABI2,PLEKHO1,ERCC2,IGSF6,VPS26C,ICA1,TJAP1,JAK2,LIG4,MEF2C,NDUFA5,OLR1,MINDY2,SIDT1,CEP97,RAD51D,RGS10,HSPA4L,DOCK10,AMBRA1,FNDC3A,SLC12A2,ZCCHC24,CDK19,TSPYL2,NXT2,VAMP1,ARHGEF9,EXOC7,SIK3,RBFOX2,METTL3,UBE2H,XRCC4,ZNF24,FTSJ1,LAMP5" Drug 663_DN U0125; Down 200; 1uM; PC3; HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADD3,BIN1,PPFIA3,NRP2,CFLAR,SYNJ1,ST3GAL5,NEURL1,CRMP1,SGSM2,DTNA,SIDT2,MBNL2,EPB41L2,KCNMB2,OLFM1,FGFR1,BAIAP2,C1orf61,CAMKK2,CELF1,SESN1,C1QL1,GLYR1,GNG3,GNG4,PRRC2B,FAM107A,PTGDR2,ARHGAP19,KCNH2,KIF5A,PAXBP1,MPP2,PBX1,PIK3R1,MBOAT7,NUDT11,SEMA6D,SBF1,ITSN1,EMC1,TCF4,SZT2,TRPM2,TRPS1,SSBP2" Drug 4575_DN Piromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "PKP4,APC,FAM131A,CACNA1A,PLAA,DNAJB5,CSF1R,ARHGEF10,PDE4DIP,CDON,FEM1B,LPAR6,EN2,EZH1,FGFR1,SCARA3,FYB1,ERAP1,SYT17,C1QL1,GLRB,GPM6B,GRM1,SHISAL1,KHK,SCAMP5,LYRM9,NDP,OPCML,PAK3,FA2H,PROX1,RAB3IL1,FNDC3A,ZNF334,BTBD7,SPTAN1,ARHGEF9,ASTN2,TCF4,CRTC1,ZNF32,WNK1,NT5M,EVI5,KCNAB1,PHTF2" Drug 6212_DN Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "PKP4,ARRB2,ZBTB10,SCARB1,RAB28,NIPBL,DCAF8,ZNF337,GIT2,DBT,DCTN1,FEM1B,FCF1,SH3GLB1,RACK1,NBEA,CINP,PDLIM5,FAM49B,SYT17,ARFIP1,MAP4K5,IL6ST,OXTR,PRKAR1B,PTPN13,BSDC1,MYH14,TCP11L1,SFPQ,SUPT20H,AMBRA1,KBTBD4,SMARCC2,WDTC1,NSFL1C,KLHL7,ANKRD12,TBL1X,TCF7,TCF7L2,TIAM1,KAT6B,HIRA,VAV1,NSD2,MPPE1" Drug 5069_DN Gemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NME5,APOC1,ARRB2,MARK4,ALDH4A1,CANX,AP4M1,CLCN4,TPP1,HOMER3,BAG4,VCAN,PARD6A,DLG3,EDIL3,EFNA3,FAM13A,MBNL2,EN2,TUBB4A,ANKFY1,EFCAB2,TRMO,DENND2A,HSF2,SHISAL1,MBD1,MIA2,MX1,SLC11A2,PAK3,PLXNB1,MAPK7,TCP11L1,SCN8A,ASAP3,DZIP1,ELMO2,TMCC1,BEX1,ZBTB43,THSD1,TIAM1,METTL3,UPF3A,MAP3K12,FZD3" Drug 7411_UP Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "RALGAPA1,ALCAM,APAF1,ARHGDIG,CDK5R1,BTRC,TPP1,NECTIN3,EDRF1,SEC14L5,C2CD2L,SMG7,EFNB3,CELSR3,PHF20L1,DENND4A,CDKL3,FGFR1,GAP43,COPS8,RNFT2,ATXN2L,ELOVL5,KIF5C,MIA2,SCAMP5,MITF,MMP16,NTRK2,MBOAT7,PRPH,ZSCAN32,RIPOR1,RAB3IL1,FAM184A,RGS12,RNASEL,GSTCD,PAQR6,SBF1,SLC11A1,KIF21B,ZC3H13,WIPF1,TFIP11,GDPD5,HPS4" Drug 2849_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AMPD3,CDC14B,CDK10,EIF4G3,CFLAR,CFAP410,CAMK2G,SRSF11,PLEKHB1,TAOK2,CLCN3,HOMER3,NCOR1,LRIG1,DAPK3,GIT2,DMTN,ACSL4,ZNF589,FGFR1,DPYSL4,TXNL4A,GLS,GPR19,NR3C1,JAK2,NPTX1,PLEC,LRP12,ZDHHC14,GTDC1,RXRA,SBF1,EMC1,CDK19,VPS13A,ARC,ANKRD28,ASTN2,SEMA4A,EXOC7,IQCE,TMOD1,TRIO,TRPC1,ZMYND8,PHTF2" Drug 5100_DN Cyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "APC,ASPH,SLC4A4,ALDH7A1,FUBP1,CACNA1A,HIP1R,MAP7,LARGE1,WHRN,HINFP,SDC3,BRINP1,DNAJC6,EDIL3,HIPK3,MBNL2,RGS17,STX2,FGFR1,SEMA4D,CGREF1,GAB1,USP19,C1QL1,CNTRL,GIT1,NFIX,STRN3,POLG,PPARA,RAB3A,BEND5,RGS4,SHANK2,MYH15,UNC5B,ATP11A,EXOC7,WSCD1,THRA,OSBP2,ZNF225,NT5M,SLC17A7,AAAS,SENP7" Drug 5274_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASPHD1,ADRA1D,ALCAM,BIN1,APC,SYNJ2,CFAP410,HAP1,CDH8,CRLF1,LY86,GIT2,DRD1,DTNA,ING4,CAMSAP1,FHL1,GCNT2,GLS,GPER1,RASSF8,ATXN2L,KIF5A,KIF5C,MBD1,KITLG,MOBP,NF1,SETD4,MBOAT7,PRKAR1B,GRAMD1C,RAD52,RGS10,SH3BP2,SH3GL3,DOCK10,FUZ,FBXO11,WDTC1,ZCCHC24,THSD1,TCF7L2,AP4E1,TRIO,ZIC3,SSPN" Drug 3965_UP PHA-00851261E [724719-49-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,KIDINS220,BEGAIN,AMH,CRLF1,STOML1,PICK1,WHRN,COL9A3,AKAP5,DGKG,CTIF,DCC,DCT,SMG7,RCAN2,ANKMY1,CACNG2,GABRA5,GPR12,STON1,SOX21,PTGDR2,ICA1,PCBP3,PCSK1,PCSK2,CAMKV,PLCD1,SMIM7,CDIP1,C1orf54,KLHDC8A,RPS20,ZFP2,SCG5,SLC1A3,UNC5B,JMJD6,TCF4,SZT2,CHST8,THBS4,TMOD1,TPM3,HIRA,LAT2" Drug 141_UP chlorpropamide; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADCY2,ANK3,APBB2,ALDH4A1,CADM3,GYG2,CACNA1I,NEURL1,CHRNA4,TAOK2,ZFYVE9,IQCK,PCYT1B,AATK,RIMS2,DAPK3,PHF20L1,SUGP2,F8,C1orf61,AGAP2,AFF2,PCDH17,RUNDC3A,MCHR1,SOX21,NXPH3,KIF5A,MAN2A2,MYT1,PC,PCDH9,PLEC,PACSIN1,PRKAR1B,ATG16L1,RLBP1,NEK11,SMARCC2,CLSTN2,HIF3A,THRA,TP53BP1,RPRM,GDPD5,MPPE1,CERS6" Drug 984_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AK2,CDC42BPA,APOC1,ASTN1,MTMR3,SGCE,CAMK2G,CRLF1,RAB28,DCT,LYPD1,DTNA,DYRK1A,CNNM1,SUGP2,LRRC23,OLFM1,PDLIM5,DISC1,TDRKH,GRIK5,NR3C1,MPP2,PFKFB2,MED1,PPP5C,WDR25,RAD52,FAM184A,RPS20,SH3BP2,KANSL3,SLC11A1,BTBD7,COA1,SNCA,RBM34,MAPK8IP3,ADGRL3,TEK,CABIN1,AMACR,VIPR2,SPHK2,MVB12B,TIGD6,RNF170" Drug 3382_UP 3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,AP2A2,CACNA1I,RHBDL1,ARHGEF2,SULT4A1,CNTFR,CNTN1,CRYM,SNCAIP,CSF1R,FAM169A,DAPK3,RUSC2,TMCC2,FRY,MTSS1L,TUBB4A,DISC1,GRB10,GRIK5,GUCY1B1,HRH3,KIF5A,MAN2A2,MAOB,TAGLN3,MYH6,MYO7A,NOVA2,POU3F4,PTPRH,CCDC40,RAD52,RPS6KA2,SYNDIG1,SMPD3,ASIC4,SOX10,HECW1,SPP1,ABCC8,SZT2,HIF3A,R3HDM1,FLRT2,STMN4" Drug 3362_DN Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASIC1,APC,MARCH3,CFLAR,USP2,ARHGAP33,TAOK2,ARHGEF10,CTH,JAKMIP2,RCAN1,DTNA,EGFR,STX2,FGFR1,DPYSL4,TPK1,INPP5K,GCNT2,TM6SF1,MEIS2,ADAM22,PLCD1,PLXNB1,PPP5C,MAPK8,GRAMD1C,RAB3A,RAD52,RALGDS,TCP11L1,SBF1,PEX26,SOX3,EMC1,TROVE2,PLCB1,KIAA1107,ZNF34,TRPC1,VLDLR,XRCC4,NDRG4,REEP1,SYNC,GDPD5,SSPN" Drug 2170_DN Solasodine [126-17-0]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADRA1D,MTUS1,AMPD3,APAF1,APOC1,NCOA1,ATP2A2,KIF1A,AP4M1,LARGE1,FOXN3,ZNF337,DGKG,DBT,HP1BP3,OPTN,EIF1,F5,FGFR1,GABRA4,SRCAP,GRIK5,IPO5,MYT1,NCAM1,SLCO1C1,CEP41,RIPOR1,SYNDIG1,FNDC3A,LIMS2,SLC11A1,BTBD7,SLC20A2,IZUMO4,ATP11A,PCDHGA10,PSD3,THRA,TMOD1,RBFOX2,TPM3,VSNL1,MKRN3,SYNC,MPPE1,SENP7" Drug 4766_DN Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARID1A,SLC12A5,SLC4A4,SCAPER,CA4,CAMK2G,ARHGEF2,TAOK2,STOML1,CRY2,CNTNAP2,RIMS2,ATN1,GNE,CNNM1,EGFR,SORBS3,AGAP2,SEMA4D,SRCAP,USP19,PCLO,NR3C1,INPP1,KCNF1,MDM4,MEF2C,MID1,SMIM7,RAD52,KCTD17,ZFHX4,ZNF821,SLC1A7,PEX26,FAM214B,CCDC88A,ZNF423,THSD1,ARHGEF9,PLCB1,AHCYL2,DICER1,THRA,TMOD1,SCG2,SEMA3B" Drug 2781_UP Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,NDRG2,AMPD3,BIN1,APC,ASPH,SYNJ2,CAMK2G,SLC16A4,RAB33A,ZFYVE9,HOMER3,SH2B1,RIMS2,INTS1,EGFR,MBNL2,FHL1,AFF2,GPER1,SPACA9,INPP5B,KCNJ5,SMAD1,MAP4,MOBP,ADAM22,NTRK2,NUMA1,MINDY2,PTN,RAD52,FAM184A,RPS6KA2,KCNIP1,SEC14L1,PPP1R9A,KDM4B,IQSEC2,TROVE2,CLSTN2,ARHGEF12,DICER1,HIRA,LMF1,WIPF1,LAT2" Drug 4540_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "DPF1,MTUS1,CDC14B,CDK10,ZSCAN18,GYG2,CACNA1G,RUNX1T1,SCARB1,NEURL1,CRLF1,ADGRG1,ASIC3,CHN2,SULT4A1,TCEAL2,EDRF1,CDON,EGFR,MBNL2,SORBS3,ING4,ETV1,REEP2,FOXG1,DCTN2,ERAP1,GFER,HSD17B1,SHISAL1,KCNJ5,ENPP2,SPATA6,TNPO2,PPP2R2B,RASGRF1,BEND5,GAL3ST4,KCTD17,MRAS,ZSWIM8,RBM26,SYT1,TACR1,TRIM2,CADM1,STMN4" Drug 3748_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACLY,ARID1A,AK2,DOC2A,GAS7,ARRB2,ASPH,MYRF,CHM,TPP1,STOML1,CHD1L,RIMS3,DCTN1,TOM1,ZNF589,GCNT2,ZNF276,SCIN,INPP5B,MAP4,NEK1,PDE4D,NLE1,SLC25A23,SAMD9,FAM120C,RAB3IL1,ACSS3,RAD52,RALGDS,FAM184A,FNDC3A,SLC4A3,CCDC88A,ELMO2,SMARCA4,CAMSAP2,ZEB1,RPGRIP1L,CHST8,TMPO,TRIO,VLDLR,SPHK2,WNK1,NT5M" Drug 1468_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "MTUS1,ATM,CFLAR,KYAT1,REPS2,FOXN3,SLC4A8,NCOR1,DCAF8,SMG7,HIPK3,SIDT2,EFNA3,EGFR,EPB41L1,FAM49B,PRELID3A,TRAF3IP2,SRCAP,GLS,GNG4,GRB10,NR3C1,DIPK1A,ITPKB,LIG4,MITF,ADAM22,NRCAM,PDE4A,SLC25A23,WDR25,FERMT1,EPN2,SHANK2,BTBD7,ZNF423,ZBTB43,EXOC7,TRIM2,PLPPR2,VGF,KLC2,EMSY,GDPD5,SEMA3B,PHTF2" Drug 5527_DN Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG3,SRPX,OGT,PPFIA3,APP,NUMB,KIF1A,SYNJ2,FAM189A2,AKAP7,MICAL2,LYPD1,EFNA3,CELSR3,SORBS3,ING4,PLEKHO1,SEMA4D,DISC1,INPP5K,BTN2A1,RNFT2,KCNJ3,LMO2,VWA5A,MIA2,MPP2,SLC11A2,PDE3B,POLG,MAPK8,PRPH,RAD52,ZCWPW1,RGS12,FUZ,ZNF365,PPP4R3A,INTS9,LIMCH1,ZCCHC24,ZSWIM8,LHPP,ATP11A,PIK3R5,PLPPR2,VAV1" Drug 1536_UP "Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "DPF1,APBB2,PLA2G4C,NUMB,SLC2A11,SYNJ2,ARHGAP33,CACNA2D2,SRSF11,HOMER3,CNTN1,SLC4A8,HDAC4,SPOCK2,DNAJC6,DTNA,MBNL2,RCAN2,BAIAP2,CAMSAP1,TRMO,PDLIM5,ATP2C1,GNAL,NR3C1,GRM1,KCNJ5,MAOB,MMP16,CD200,PDE4A,SERPINE2,CEP41,ELOVL2,FAM120C,ROBO1,EMID1,SEMA6D,STUM,ZNF365,BTBD7,SLN,SPART,TTBK2,VAV2,ZBTB14,RNF170" Drug 4101_DN Betulinic acid [472-15-1]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ANK3,GAS7,ALDH4A1,ST3GAL5,LARGE1,CHM,ENTPD4,ARHGEF10,VCAN,PDE4DIP,DBT,SMG7,EIF4G2,PLEKHO1,COQ7,ZNF549,ETV1,MSL3,LIG4,MBD1,NUMA1,CLDN11,PAK3,PLCD1,STRN3,MINDY2,PPP5C,WDR25,ZSCAN32,RAB3A,FBXW7,IL17RB,SELL,ANKRD6,PEX26,SLN,COA1,UNC5B,EXOC7,KIAA1107,DICER1,GPR161,SSBP2,HIRA,SEMA3B,PHTF2,AAAS" Drug 1853_UP Diprophylline [479-18-5]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABR,AGT,AMT,APAF1,PDXK,CASK,ATP6V0A1,CACNB2,ZFYVE9,TPP1,HOMER3,DAPK3,GSDME,FCF1,EFNA3,FGFR1,EFCAB2,AHDC1,LIG4,MAP4,N6AMT1,NEFH,SMOX,ZNF426,MAPK3,MAPK8,PTAFR,RAD51D,RXRA,GALNT10,ITSN1,DZIP1,SLC2A5,PEX26,ZNF667,TNIK,TSPYL2,TROVE2,NCDN,RGL1,TCF7L2,ARHGEF12,RBFOX2,TPD52,SMUG1,ZMYND8,VIPR2" Drug 3884_DN Phenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "MRTFA,BIN1,APBB2,PLA2G4C,CDK13,SLC2A11,ALDH7A1,KIF1A,CA4,CA12,KYAT1,CLGN,FADS2,SH2B1,USP6NL,RIMS3,CTIF,ZNF804A,ATN1,ERCC2,SCARA3,NOP56,OGA,SEPT9,GCNT2,SRCAP,C1QL1,GPER1,GRM8,AGBL5,KCNH2,KHK,NRGN,NTRK2,PIK3CD,TNPO2,MAPK8,RAD52,RGS12,RPS6KA2,RASA3,LIMCH1,SNCA,MAPK8IP3,EXOC7,ARHGEF12,THRA" Drug 7021_UP Ethamivan [304-84-7]; Up 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,ADCY2,MRTFA,PPFIA3,PDXK,ADAM23,SYNJ2,CDK5R2,SLIT2,EPS15L1,CLCN4,SLC4A7,SIPA1L1,SOCS5,RIMS2,GPRASP1,SHANK1,DTNA,EDNRA,PHF20L1,ELAVL3,DLC1,FYB1,GAD1,GRIN1,GPR45,ELOVL5,KCNF1,IPO5,MAP4,MEIS2,MGAT3,KITLG,ADAM22,NASP,PDE3B,PIK3CD,PEX5,RIPOR1,RGS12,ARHGAP26,CLASP2,TRO,PLPPR2,ZBTB14,ZNF74,PRDM2" Drug 3543_UP Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "DPF1,ADGRF5,ALCAM,SRPX,APBB2,SEMA4G,AZGP1,CFLAR,CACNA1I,LDLRAD4,CDC42,SLIT2,ARMC8,SNCAIP,SOCS5,NOS1AP,DOCK4,RASSF2,DTNA,SORBS3,IGSF6,ZNF589,FECH,KHDRBS3,FYN,GALC,MALT1,GRM3,HNMT,IL6R,KPNA5,MSR1,NOVA2,NPR2,PLP1,MINDY2,PPP2R2B,RAD52,FAM184A,SYBU,PDZRN3,SS18,SYT11,KIAA1107,DMXL2,UBE3A,XRCC4" Drug 4836_DN Dydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADRA1D,MRTFA,AMT,MTMR2,C5,CAMK2G,SCARB1,ARHGAP33,RAB28,WHRN,AKAP12,ZNF337,ZNF804A,MFAP3L,G3BP2,SORBS3,MTSS1L,ERCC2,EZH1,KAT8,GPD2,GPER1,TJAP1,TM6SF1,GIT1,NF1,PRODH,GON4L,PEX5,RAB3IL1,RGS12,RNASEL,FBXW7,SUPT20H,SH3BP2,FAM214B,SNCA,TAB2,TROVE2,TTBK2,PHLDB1,STX1A,TNS2,CHST8,SPHK2,MPPE1,SMIM8" Drug 7510_DN 0393-0188; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG3,ASPH,ADAM15,CNOT8,QKI,SLC4A7,ENTPD4,MATR3,HP1BP3,SPOCK3,YAF2,ELAVL2,EPB41L2,FHL1,OGA,COPS8,GNAS,NUDT21,JAK2,NF1,NFYA,ZFYVE21,LRRN3,BCAS3,ZSCAN32,GTDC1,RGS4,SH3BP2,SH3GL3,WDR37,SLC4A3,KIF13A,LMBRD1,WDTC1,TNIK,ZBTB43,TAB2,ACSBG1,FBXW11,TRIM2,TPD52,NR2C2,HIRA,UBE2H,NSD2,TRIM9,FZD3" Drug 1048_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABAT,PPFIA3,STX16,CDK5R1,SYNJ2,PTBP2,COL4A5,RNF14,SOCS5,DLG3,DMTF1,E2F5,TSPAN5,SH3GLB1,ABI2,EGR3,CDKL3,ECSIT,SCML2,NOP56,FAM49B,FYN,NCKAP1,SEPT9,INPP5K,GLYR1,GPR19,GRB10,FICD,JAK2,NAP1L1,PCDH9,RETREG1,KCTD15,SMOX,MBOAT7,KLK6,NKAIN1,TRA2B,SGK1,SOX3,ZBTB43,KIAA0930,TRIM2,SF1,ZNF24,ZBTB38" Drug 2988_UP Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABAT,GRAMD1B,AMPH,LGR5,PDE8B,DDX3Y,CACNG1,HIP1R,CDH10,QKI,SLC4A8,TCEAL2,CRMP1,TOX,MFAP3L,SPOCK3,EXOG,FCF1,CNNM1,RRAGB,FHL1,FOXG1,GABRG2,NCKAP1,GFER,GLS,PCSK1N,PRUNE2,GPM6B,PTGDR2,ATXN2L,MDM4,NPPA,PTAFR,RFX2,RGS12,PNMA8A,SNCA,EMC1,MAPK8IP3,TACR1,DNMBP,PHF24,AHCYL2,TPM3,TRH,SPHK2" Drug 1698_UP Isoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADRA1D,APOC1,BACH1,SCAPER,B4GALT6,RAB28,ZFYVE9,BAG4,CRMP1,GPRASP1,SPOCK2,EDNRB,MBNL2,PLXNC1,NCALD,F3,BAIAP2,FHL1,CGREF1,NCKAP1,GRIK5,MAN2A2,NDUFA5,NEK1,NF1,NFYA,CNOT4,MED1,PRKCB,MAPK8,RAD52,ZNF821,FNDC3A,RAB3GAP1,BTBD7,KIF13A,SPART,STX1A,PLCB1,ARC,FBXW11,TEX15,TK2,DAAM2,LMF1,ZNF45,SSPN" Drug 3183_DN "Methylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADCY6,ALCAM,DOC2A,TRMT9B,CDK10,ATP2A2,CFLAR,SYNJ2,SCAPER,CFAP410,CACNA1D,SOCS6,FAM169A,DCAF8,CTIF,CNNM1,OPTN,EIF5,BAIAP2,SEMA4D,GAB1,ZNF44,TRAF3IP2,ERAP1,COPS8,GOLGB1,GRM1,MAP4,NUMA1,OGG1,MAPK7,ZCWPW1,GTDC1,RGS3,PPP4R3A,KIF13A,WDTC1,ZBTB43,STX1A,VAMP1,ATP13A2,SLC44A1,TMOD1,CABIN1,ZKSCAN5,HIRA,SSPN" Drug 2307_UP Trimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASIC1,ADORA2A,KIDINS220,SPARCL1,ALK,MRTFA,APBA2,CDK13,RASL11B,DDX3Y,GYG2,DCLK1,DCAF4,SEC14L5,ELAVL3,ERCC2,APC2,TPK1,FYN,GABRG2,GLS,IRAK3,GPR45,ITPKA,MAP2,MID1,ADAM22,NPR2,POU3F4,MAPK7,RELN,PTPRO,RGS7,SBF1,TRIM46,SH3BP2,SHANK2,POPDC3,ATP11A,RPGRIP1L,PSD3,OBSL1,TMOD1,TRPC3,OSBP2,MKRN3,AP3B2" Drug 1691_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,NME5,DOC2A,ATP6V0A1,HAP1,SCARB1,RAB28,CLU,FADS2,AKAP7,NECTIN3,CTIF,JAKMIP2,HP1BP3,PARD6A,EFNA3,RGS17,RRAGB,RUNDC3A,TDRKH,GRB10,HNMT,ICA1,INPP5B,KCNMA1,MAP4,TAGLN3,MX1,NUCB1,NUMA1,PCDH9,PENK,WDR25,RAD52,ROM1,ASAP3,FBXO11,ABLIM3,PEX26,ZCCHC24,SPART,JMJD6,EHBP1,TCF7L2,TRIM2,HIRA,RNF146" Drug 6237_UP Cefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,AP2A2,BCAS1,PDE8B,DNAH17,RGS11,ARHGEF1,CDH10,CHN2,CLCN3,VAX2,COL9A3,PDE4DIP,SPOCK2,FECH,FGF12,FHL1,EFCAB2,GABRA2,ERAP1,GRM8,MAP4K5,KHK,NRGN,LRRN3,SAMD9,FAM120C,KHDRBS2,RGR,RNASEL,ZNF821,MRAS,FAM214B,MAPKBP1,SNCA,PHLDB1,ASTN2,WSCD1,KIAA0930,TCF7L2,TNS2,UBTF,MICAL1,REEP1,EMSY,ADAMTS9,SEMA3B" Drug 3445_UP Vidarabine [5536-17-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "BIN1,RGS20,SLC2A11,CFLAR,RCBTB2,FADS2,ENTPD4,CSF1R,GREB1,NOS1AP,CDON,GNE,ANKMY1,REEP2,FGFR1,CAMSAP1,FHL1,FOXG1,PDLIM5,GPR153,SEPT9,TXNL4A,GNAS,GPR19,GRM7,ITPKB,KHK,MITF,ZNF862,NDUFA5,PENK,C19orf57,PRKAR1B,GTDC1,EMID1,RXRA,ASAP3,FAM214B,KANSL3,SNCA,TMCC1,WDTC1,SPTAN1,TMEM121,SLC44A1,NDRG4,AP3B2" Drug 2034_DN Josamycin [16846-24-5]; Down 200; 4.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARID1A,BRAP,ALAD,AMPD2,APP,BACH1,RAB29,CARS,ENTPD6,SMARCAL1,CSF1R,DCAF8,ZNF337,ZNF804A,KIAA0753,DTNA,ANKRD46,SIDT2,IGSF6,EZH1,SEC23B,FYN,CRCP,SPIN1,PRRC2B,IRAK3,KTN1,MAN2A2,MARK3,AFF1,MTR,NEFH,NFYA,OPA1,CDK14,MBOAT7,FAM192A,ATXN2,SPART,MAPK8IP3,DIP2A,GSE1,ANKRD12,CABIN1,RBFOX2,TSC2,ZNF189" Drug 3584_DN Mesalamine [89-57-6]; Down 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "APC,PRX,PPP4R4,ARRB1,DNAH17,MARK4,ASPH,KIF1A,CA12,TAOK2,CLU,FADS2,SULT4A1,CRY2,MFAP3L,DNM1,EDNRA,FCF1,NCALD,USP19,KCNMB4,ATXN2L,INPP5B,MAP4,MMP16,NF1,CNOT4,NPR2,PLXNB1,STRN3,MAPK7,PTHLH,SH3BP2,ASAP3,FUZ,NLGN1,EPN2,SLC6A8,SLC22A4,KDM4C,SPTAN1,NCDN,STX1A,SEMA4A,EXOC7,MICAL1,WIPF1" Drug 3299_DN Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASIC1,PLA2G6,AMT,APOC1,PPFIA3,MARK4,ALDH4A1,CFLAR,GYG2,B4GALT6,FAM189A2,CSNK1E,EDRF1,MAML1,GIT2,LYPD1,KBTBD11,ACSL4,FGFR1,GPER1,CACFD1,ICA1,LIG4,MPP2,GIT1,NEK1,NF1,LRP12,PPP3CC,SIDT1,TMEM104,RGS10,SH3BP2,AMBRA1,BTBD7,UNC5B,STX1A,VPS13A,TACC1,PSD3,ATP13A2,TK2,WNK1,EMSY,PCBP4,MVB12B,SSPN" Drug 5410_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NME5,EPB41L5,ARHGDIG,ALDH7A1,CDK5R1,SLIT2,BAG4,ENTPD4,SH2B1,SIPA1L1,EDRF1,DCAF8,ING4,KAT8,ZNF589,FGFR1,BAIAP2,CINP,OGA,SRCAP,MSL3,GPER1,ELOVL5,HNMT,IL6ST,INPP5B,KCNJ3,IPO5,LSS,MBD1,MPP2,NCAM2,NUMA1,PRKAR1B,PRODH,ZDHHC14,GTDC1,RGS12,SLC1A7,RBM34,INKA2,KAZN,EXOC7,TCF7L2,TRIM2,KCTD2,ZNF45" Drug 5597_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "PLA2G6,APBB2,CAMK2G,CRY2,CNTNAP2,SMG7,RABGAP1L,ATN1,EFNA3,RBM12,EFEMP1,FGFR3,DPYSL4,GPR153,MALT1,RAB30,POLL,GRIK5,INPP5B,ITIH2,JAK2,KHK,KIF5C,LIG4,VWA5A,OGG1,PC,PPP5C,PRKAR1B,FAM120C,NKAIN1,RAB3A,SHANK2,SLC20A2,LIMCH1,ZCCHC24,CLASP2,CLSTN2,CEP68,ASTN2,SEMA4A,TNS2,TMEM121,CDK20,LMF1,SYNC,EMSY" Drug 3277_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,ADORA1,AMPD3,CDC14B,ARRB2,ASPH,ATP6V0A1,BCL7A,CACNA1I,LDLRAD4,BTRC,PTBP2,USP2,EPS15L1,CLU,DNAJB5,PICK1,ENTPD4,SNCAIP,EDRF1,RIMS3,DTNA,EGR3,SORBS3,DMTN,OLFM1,IQCG,GRM7,INPP1,MDM4,MX1,ZNF862,NELL2,NUMA1,LRP12,RAB3IL1,MYH14,RYR1,TRA2B,ZNF365,RAB3GAP1,ARHGAP26,CAMTA2,STX1A,CHST8,KCNK12,UBE3B" Drug 3355_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AP2A2,LTBP4,CACNA1A,CACNG1,CAMK2B,NCOR2,DZIP3,RIMS2,SPOCK2,CTIF,BRINP1,HIPK3,ETV1,SCML2,ZNF589,FHL1,RND1,ADAMTS13,NR3C1,GRM2,IL1RAPL1,IRF8,MMP17,TAGLN3,MYCN,NEK1,KCNK10,CDIP1,LRP12,CEP41,MAPK7,CCDC40,TRIM68,EMID1,KCNIP1,ASAP3,SLC1A2,WDTC1,EMC1,ZC3H13,SPTB,ATP10B,ACSBG1,JMJD6,EXOC7,GPR161,TNS1" Drug 6800_DN Chlorthalidone [77-36-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,NME5,SEMA6A,ALCAM,PLA2G4C,KIF1A,BMP7,CAMK2B,SPAG9,FOXN3,CHM,SMARCAL1,CRY2,PDE4DIP,SDC3,RCAN1,TSPAN5,SIDT2,ELAVL3,STX2,NCALD,ZNF589,HBS1L,GLS,POLL,FERMT2,GPD2,GSN,HSD17B1,INPP5B,MIA2,NOS1,NUCB1,PCDH9,SBF1,EPN2,SHANK2,ZBTB43,VAMP1,KAZN,EXOC7,TCF7L2,TMOD1,TFIP11,EPM2A,MARCH8,UBE3B" Drug 5360_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADCY6,SEMA6A,APBA2,BCAS1,ARHGDIG,ATM,BCL7A,CFLAR,ST3GAL5,RCBTB2,FAM189A2,AKAP7,NCOR1,MFAP3L,SGK2,F5,DLC1,ZNF589,FHL1,SEMA4D,PRELID3A,ZNF276,TXNL4A,MSL3,POLL,GUCY1A2,KCNK2,MAP4,MATK,ZNF862,NF1,NOS1,KCNK10,PRKAR1B,MAPK10,PPP1R9A,FUZ,FNDC3A,KIF21B,DOK5,ZBTB43,TRIM2,NSD1,ARHGEF12,TMEM121,NR2C2,MPPE1" Drug 5292_DN Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARID1A,APC,CFLAR,SYNJ2,SCARB1,SLC4A7,LRIG1,FAM169A,DZIP3,GREB1,CTNND1,ARHGAP32,GIT2,DCTN1,HP1BP3,PARD6A,DLG3,WAC,TBC1D16,POLR1B,FAM49B,CGREF1,ZNF44,PRRC2B,IL6ST,INPP5B,KIF2A,MEIS1,MMP16,NF1,NPR2,NLE1,PMS2,PRKCZ,ARHGEF10L,MAPK12,FERMT1,EMC1,ZBTB43,SS18,NCDN,FAM168A,EXOC7,ATP13A2,TMPO,LMF1,MPPE1" Drug 7358_DN Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASIC1,AP2A2,BIN1,CDC42BPA,APLP1,APOC1,CDK13,CFLAR,C5,ARHGEF1,PLEKHB1,TAOK2,HOMER3,SDC3,MFAP3L,TMCC2,CDON,EDNRA,EFNA3,DMTN,LRRC23,KIAA1109,GPR153,INPP5K,GLYR1,GPD2,DHX35,KCNH2,MAP4,KITLG,AFF1,MMP16,STRN3,NEK11,EMID1,PPP4R3A,SLC20A2,ZKSCAN3,COA1,SNCA,ELOVL4,ARHGEF12,TK2,CABIN1,TRPC1,SYNC,SSPN" Drug 1279_UP Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "CDC42BPA,GAS7,APP,CDK13,CAMK2G,IQCK,CSNK1E,DAPK1,RUSC2,C2CD2L,SV2B,RABGAP1L,COQ7,DENND4A,FECH,HBS1L,TXNL4A,OS9,ELOVL5,MAP4,NFYA,PPP3CC,MAPK7,CNTLN,PTAFR,ZDHHC14,LGR4,URGCP,EPN2,DHX30,SLC11A1,SHANK2,SLC20A2,TMCC1,WDTC1,UNC5B,ZBTB43,RGL1,ATP13A2,ZNF34,TMOD1,TST,HIRA,XRCC4,WNK1,NLRP3,ZNF248" Drug 2985_DN "Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ANK3,PPFIA4,APBB2,BCL7A,SCAPER,CACNB4,SOCS6,TAOK2,HOMER3,IQCK,ARHGEF10,PDE4DIP,SLITRK5,RUBCN,DYRK1A,EEF1A2,LRRC23,RASGRP2,DLC1,ZNF589,KIAA1109,INPP5K,AHDC1,ADAM28,GNAS,GPM6B,RETREG1,PPARA,PLPPR1,ZCWPW1,KHDRBS2,ZDHHC14,RGS10,TCP11L1,SYNDIG1,FAM214B,SNCA,IZUMO4,SPTAN1,AHCYL2,SLC44A1,TNNT1,TPM1,TRO,EVI5,PCBP4,PARP11" Drug 2915_UP Ethamsylate [2624-44-4]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADD2,SLC12A5,CDC42BPA,ANK3,PRX,PPP4R4,PDE8B,DDX3Y,ADGRB1,BTRC,THSD7A,INA,MAGI1,PLEKHB1,ZFYVE9,CLCN4,NRXN1,MICAL2,DAPK3,SV2B,ST8SIA3,SORBS3,TBC1D16,OLFM1,FOXG1,KHDRBS3,NEU3,SPACA9,MYO6,NOVA2,NPPA,NTRK2,EPB41L4B,PRPH,RIPOR1,IL17RB,CXXC4,SORCS3,SMARCD3,LIMCH1,ARHGAP26,RAP1GAP2,ZNF34,TIAM1,TJP1,TPM3,CLIP2" Drug 2512_DN Anabasine [494-52-0]; Down 200; 24.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "MRTFA,APC,NCOA1,N4BP2L1,ADAM23,ST3GAL5,SYNJ2,ENTPD6,CDH10,HOMER3,RUSC2,TRAPPC9,DTNA,MRNIP,RASGRP2,VPS26C,ZNF589,SEPT9,LILRA2,SLC2A6,MYT1,NCF2,NEFH,NF1,CNOT4,RETREG1,PLCB2,PLTP,LRRN3,FAM120C,RAB3A,RAD52,GSTCD,FAM102A,FAM214B,ARHGEF40,MYH15,KDM4C,PLCB1,EXOC7,CAMSAP2,RBFOX2,FLRT2,XRCC4,ZNF32,UPF3A,ST7" Drug 4793_UP Zardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SEMA7A,APBA2,APC,APOC1,ARNTL,ATM,ATP6V0A1,SYNJ1,BTRC,CAST,TCEAL2,NECTIN3,DCT,ING4,EFS,ACSL4,OLFM1,FGF13,PRKAG2,IQCG,GABRA2,DISC1,GRB10,ICA1,DIPK1A,ITIH2,MAN2A2,RAP1GDS1,KCNIP1,SH3GL3,CCDC88A,LIMCH1,UHRF1BP1L,TROVE2,NXT2,MAPK8IP3,NEK4,PLCB1,TLR4,TMPO,PIK3R5,TRPC3,SSBP2,DNAJC12,CLDND1,ZFAND5,SLC17A7" Drug 7514_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "KIF1A,NRP2,CALB1,ARHGEF1,AKAP7,NCOR1,CSF1R,SIPA1L1,SEC14L5,TBC1D5,CTIF,DPH1,TOM1,EDN3,EPB41L2,DMTN,LRRC23,MPP6,MSL3,ATXN2L,TJAP1,KCNJ5,IPO5,MAN2A2,MYT1,OCRL,CDK18,PDE1C,NECAB2,MAPK7,MAPK8,GSTCD,EMID1,CLIP1,FAM214B,SLC20A2,RCOR3,DOK5,HECW1,SYT11,FBXW11,DOCK9,ARHGEF12,PIK3R5,TPM2,TRIO,LAT2" Drug 1219_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "APOC1,PPFIA3,SHROOM2,STX16,BACH1,CFAP410,ARHGEF2,ZMYM4,EPS15L1,CLU,ARMC8,ABI3BP,CRY2,GIT2,EDIL3,STX2,FGF1,FOXG1,CAP2,SEMA4D,DLL3,FYB1,SYT17,INPP5K,ALDH1L1,STON1,GRM1,AFF1,MMP16,NACA,NAP1L2,OXTR,PDE4D,PIK3R1,RETREG1,LRRN3,HSPA4L,ITSN1,PPP1R9A,PDZD2,KDM4C,ZBTB43,RAP1GAP2,PHLDB1,ARHGEF9,MTCL1,SCG2" Drug 6313_DN "Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "C1QTNF1,ASPH,MPDZ,CFLAR,CCNT1,BAG4,ZFYVE16,ZNF337,DBT,SPOCK3,FEM1B,OPTN,F8,FGFR1,CAMSAP1,FYN,NCKAP1,INPP5K,CRCP,IPO5,MEIS1,MMP16,MN1,SETD4,PCDH9,PIK3R1,CNNM2,BCAS3,ZSCAN32,PTPN13,SH3TC2,RBBP6,TMEM156,SAFB,SMARCC2,ARHGAP26,ZBTB43,COLGALT2,ELOVL4,MLST8,TRIM2,TNS1,HIRA,MICAL1,LMF1,ZNF45,PLSCR4" Drug 5016_DN Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,C1QTNF3,DOC2A,APBA2,GAS7,APP,ARRB1,PDE8B,KSR1,ZFYVE9,RIMS2,RASSF2,KIAA0586,DBN1,EFNA3,DMTN,ANKMY1,FECH,GPR153,TRAF3IP2,SRCAP,FERMT2,GPD2,GRM1,TJAP1,IGSF1,MAPT,MATK,MPP2,ZNF862,NF1,NLE1,PRKAR1B,ZSCAN32,FAM120C,RAD52,ATXN1,SH3BP2,SLC1A7,BTBD7,SLN,TSPYL2,TRPC1,XRCC4,WNK1,PRDM2,GDPD5" Drug 4966_DN Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,AMT,ANK3,APP,ASPH,ALDH4A1,CFLAR,BTRC,KYAT1,KRIT1,B4GALT6,QKI,ARHGEF4,PPP6R2,HDAC4,RIMS3,MFAP3L,RABGAP1L,ACOT8,MBNL2,EPB41L1,EZH1,BAIAP2,CRCP,BTN2A1,RNFT2,MBP,NRGN,PDE3B,SLC25A23,PTHLH,RAD51D,RAP1GDS1,ARHGEF10L,GSTCD,SYBU,PEX26,FAM214B,CDK5RAP2,RCOR3,WDTC1,THSD1,STX1A,ARHGEF9,SLC44A1,KAT6B,CABIN1" Drug 3762_DN Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADD2,MRTFA,APC,BMP7,SYNJ1,MYRF,SOCS6,PLEKHB1,HOMER3,COL9A2,PHF14,TRAPPC9,EFNA3,FAM13A,PTK2B,CINP,GFER,GLYR1,KCNMB4,GPM6B,ELOVL5,SHISAL1,ZNF862,CNOT4,NPR2,PDE4A,ACSS3,RPS6KA2,ST6GAL1,DZIP1,OGDHL,ZNF415,KDM4B,ZHX3,ATP10B,THSD1,SS18,ST5,ARC,SYN2,SYT1,TBCEL,TIAM1,WNK1,SCG2,KAT6A,TIGD6" Drug 3549_DN Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "SLC12A5,AK2,PPFIA3,PLA2G4C,BCL7A,CFLAR,ST3GAL5,CACNB2,KYAT1,MAGI1,TMEM184B,AKAP7,ABCG1,TRAPPC9,DSCAM,SIDT2,CELSR3,FAM49B,INPP5K,STON1,KCNJ3,TM6SF1,MEIS2,MIA2,MPP2,ADAM22,NEK1,NF1,NFYA,NRCAM,PPP5C,ATG16L1,TRA2B,SH3BP2,PPP4R3A,SLC20A2,LIMCH1,ZHX3,SS18,CEP68,PJA1,EXOC7,NPL,ZBTB14,ZNF24,MARCH8,NUP214" Drug 6813_UP 6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ASIC1,LTBP4,AMT,ALDH4A1,SYNJ1,HIP1R,ARHGEF1,ARHGAP33,CLGN,RCBTB2,SULT4A1,LY86,RCHY1,CPS1,VCAN,MAML1,DAPK1,SPOCK2,GIT2,DMPK,DRD1,DTNB,GNG3,GRM1,GUCY1A2,HNMT,ICA1,VWA5A,MID1,PENK,CAMKV,TCP11L1,ABLIM3,SLC1A7,BTBD7,KIF13A,FAIM2,DOP1A,PDZD2,ZCCHC24,CLSTN2,SYT5,SYNE1,OBSL1,UCHL1,OSBP2,KAT6A" Drug 4771_DN Probenecid [57-66-9]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "CFLAR,QKI,HOMER3,USP6NL,DBT,SMG7,FEM1B,ABI2,COQ7,EZH1,ZMYND11,GLS,GPD2,BTN2A1,MAPT,MBNL1,MTR,NCAM2,NUMA1,ODF2,PDE3B,PIK3R1,RETREG1,POLG,TMEM231,ZDHHC14,RGS10,SLC25A36,FERMT1,AMBRA1,PEX26,SHANK2,TROVE2,POGZ,ELOVL4,TACC1,TBL1X,TCF7,TCF7L2,TMPO,RBFOX2,UBE3A,UBTF,MPPE1,KAT6A,JMJD1C,FXR1" Drug 4666_DN Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "PPFIA4,ASPH,ATP1A3,RAB28,SH2B1,MICAL2,PDE4DIP,TOX,SGSM2,KBTBD11,DTNA,EDN1,EDNRA,EN2,MTSS1L,DENND4A,CDKL3,ST3GAL6,TESK2,FER,GRM1,TJAP1,KIF2A,MAPT,MDFI,MMP16,MX1,NF1,CNOT4,PLCD1,MAPK7,ELOVL2,FAM120C,TMEM231,ZCWPW1,TTLL7,ROM1,MCMBP,FNDC3A,ZNF667,ARHGAP26,LHPP,ASTN2,FBXW11,THRA,TIAM1,WIPF1" Drug 1275_UP Bezafibrate [41859-67-0]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABAT,ABHD6,MRTFA,EP400,STX16,BCL2L2,CAPN3,NFS1,IQCK,RCHY1,CREM,CRMP1,OSBPL3,SIPA1L1,VCAN,DLG4,RCAN1,SIDT2,EFNA3,FAM13A,COQ7,CDKL3,INPP5K,ZNF276,JAK2,LIG4,LSS,NFYA,SLC11A2,PDE4B,PLTP,CNTLN,ZNF821,GALNT10,ANKRD6,PEX26,SLC11A1,SNCA,TMCC1,EMC1,SS18,MAPK8IP3,CAMSAP2,OBSL1,TNS1,TPM1,NPDC1" Drug 5447_UP Isradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,ALK,BIN1,MYRF,LDLRAD4,CCKBR,TAOK2,CLTB,PICK1,GREB1,SLC12A6,DRD1,SGK2,ING4,LRRC23,VPS26C,DLC1,FOXG1,ERAP1,ICA1,TJAP1,KCNB1,KCNMA1,PACRG,MAP4,MAPT,LRP1B,NF1,OPCML,PTHLH,PTPRH,RAB3IL1,RGS12,CNKSR2,RIMS1,ZHX3,SPTB,TROVE2,JMJD6,ABCC8,WSCD1,CRTC1,CHST8,CHST5,TRPC1,NT5M,AP3B2" Drug 6252_UP Hexestrol [84-16-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "AMPD3,AMT,APBB2,CACNA1D,CAMK2B,TPP1,VAX2,CREM,HAPLN1,CRY2,CSF1R,DBT,JAKMIP2,RCAN1,DTNA,CNNM1,MBNL2,EGR3,PLXNC1,ENO2,PIPOX,FLNC,GAB1,B4GALNT1,MALT1,GLS,GRB10,GRM1,IL6ST,INPP1,KHK,NPR2,PPP2R5C,SAMD9,PTX3,ATG16L1,C1orf54,SGK1,SLC1A7,SMTN,TSPYL2,SYT11,TGFBR3,SLC44A1,TPM1,PRDM2,UBE3B" Drug 6547_DN prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN1,APP,RGS20,MARK4,ADAM15,CFLAR,KRIT1,SCARB1,AKAP7,NRG2,TBC1D5,SPOCK2,TMCC2,DPH1,RCAN1,MAMLD1,FCF1,OPTN,ELN,EML1,LRRC23,FGF13,GRK4,GUCY1B1,KCNMA1,NUMA1,PALM,SERPINI1,SPATA6,MAPK7,WDR25,PTX3,RAB3IL1,SLC4A3,TMCC1,SMG6,TCF7L2,TRIM2,SYNE1,GPR161,TNS1,AMACR,VGF,LAT2,MAP3K12,PRDM2,ACTR3B" Drug 6930_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "APP,MADD,NUMB,KIF1A,BACH1,MPDZ,CFLAR,SYNJ2,REPS2,FOXN3,RAB28,CLCN3,CREM,CSNK1E,ZNF337,RABGAP1L,PHF20L1,EIF5,VPS13B,CGREF1,GART,SLC2A6,ATXN2L,AGBL5,KCNJ3,OGG1,SSH1,POLG,PRODH,PEX5,RIPOR1,HSPA4L,AMBRA1,PDZRN3,ERC1,SEPT8,DIP2A,TCF7,PSD3,TPD52,TRIO,TRPC1,REEP1,ZNF184,HPS4,PCBP4,JMJD1C" Drug 1371_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ARID1A,APP,ATP2B1,WASF1,KRIT1,SRSF11,CNOT8,SOCS5,APPL1,ARHGAP32,DCAF8,ZEB2,EGR3,VPS26C,ACSL4,SEC23B,ERAP1,SRCAP,IRAK3,KTN1,NFE2L2,GPSM2,PPM1B,RBBP6,MSANTD2,CLIP1,ATXN7,HSPA4L,KBTBD4,SMARCC2,GLT8D1,EMC1,SPART,TROVE2,EPB41L3,LARP4,KLHL7,ANKRD12,FAM208A,ATMIN,TCF4,TMPO,TNS1,WIPF1,ZNF189,EVI5,VPS35L" Drug 3836_DN N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ADRA1D,MRTFA,CDC14B,BAIAP3,SRSF11,PLAA,NMT2,CSF1,HDAC4,HSD17B14,DMTN,ANKMY1,FOXG1,SEMA4D,CINP,MSL3,STON1,SLC2A6,HNMT,IL6R,ADAM22,NF1,CNOT4,NPTX1,NTRK2,PFKFB2,NLE1,RAD52,ZMAT4,CCDC25,NEK11,EMID1,SH3BP2,ASAP3,SLC1A7,FAM214B,ZKSCAN3,SMARCD3,THSD1,NSFL1C,VPS13A,CABIN1,VIPR2,LAT2,KCNK12,ZNF45,REEP1" Drug 7478_UP Mefexamide hydrochloride [3413-64-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "BEGAIN,AMH,APOC1,ARHGDIG,MARK4,SLC4A4,ALDH7A1,SYNJ1,C5,RUNX1T1,HOMER3,CREM,ENTPD4,CRY2,SIPA1L1,SEC14L5,MFAP3L,HIPK3,MBNL2,ERCC2,KAT8,FGFR1,BAIAP2,OGA,GPR37,RNFT2,DHX35,ITIH2,KCNH2,KCNJ3,LMO2,MAP4,MAPT,NOS1,PDE3B,ZMAT4,PNMA8A,PAQR6,MAPK12,FAM214B,INKA2,FAM168A,ANKRD12,KIAA0930,KCTD2,ZNF24,SCG2" Drug 3467_DN Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ABHD6,NDRG2,PPFIA3,ASPH,MTMR9,GYG2,BTRC,TAOK2,VAX2,DBN1,DNM1,DSCAM,DTNA,PLEKHO1,LRRC23,INPP5K,GNG4,LPAR4,ATXN2L,TJAP1,IGSF1,MPP2,ADAM22,NRGN,SSH1,NLE1,LRRC49,WDR25,ZSCAN32,CEP97,RAD51D,ARHGEF10L,SHANK2,LIMCH1,RBM34,CEP68,TTBK2,SEMA4A,EXOC7,TCF7L2,AHCYL2,TMOD1,CDK20,PLPPR2,KCNK12,SMIM8,NUP214" Drug 2689_DN clozapine; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "NDRG2,MTUS1,FAM131A,CDK10,SLC4A4,MPDZ,INA,CLGN,TAOK2,STOML1,QKI,HOMER3,CREM,SH2B1,CSF1,EDRF1,ARHGAP32,ZNF337,TM9SF4,C2CD2L,DSCAM,EGR3,ERBB2,CSPG5,DISC1,ZNF276,LIG4,SMAD1,MAP4,MDM4,MEF2C,NF1,CNOT4,PDE4A,PRKCZ,RGS3,TCP11L1,MRAS,RASA3,SH3BGR,MLC1,WWC1,TPM3,ZMYND8,CLIP2,ZNF711,SPHK2" Drug 3165_DN Retinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "BCAS1,ARRB2,ATP6V0A1,CFLAR,BMP7,SOCS6,COL4A5,AKAP12,PDE4DIP,SDC3,GREB1,KBTBD11,TSPAN5,EGR3,COQ7,DMTN,LRRC23,SCML2,GHR,TXNL4A,POLL,NR3C1,HNMT,BRINP3,KCNH2,KHK,NFYA,PRKACB,RAB3A,CEP97,RGS10,RGS12,SLC1A7,KIF13A,WDTC1,VAMP1,TACC1,TCF7L2,TNS2,AHCYL2,CHST8,SSBP2,HIRA,PLPPR2,VIPR2,HPS4,EPM2A" Drug 4797_UP Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ALK,APBA2,CDK10,BRINP2,SLC4A4,CADM3,SCAPER,ARHGEF2,PLEKHB1,CHRNA4,DNAJB5,COL9A3,AKAP5,CREM,DTNA,ZNF589,IQCG,GABRA2,SIGLEC8,GRIK5,NR3C1,GRM7,GSN,KLF12,SYNPO,INPP5B,ITIH2,KCNJ5,KCNMA1,NPTX1,PALM,LRRN3,RGS7,TTLL7,MRAS,ST6GAL1,CNKSR2,SLCO1A2,WDTC1,SOX10,ZC3H13,CRTC1,TK2,CHST5,VAV2,ZNF24,NT5M" Drug 2444_UP Epiandrosterone [481-29-8]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.84E-03 1.00E+00 1.17E-02 1.33E-01 47 197 "ACTN2,ADORA1,CDC42BPA,PPFIA3,CDC14B,ALDH4A1,KIF1A,MPDZ,THSD7A,CHN2,CHRNA4,DZIP3,MFAP3L,SMG7,SORBS3,EIF1,ERBB2,ANKMY1,BAIAP2,GAD2,SEPT9,ADAM28,GNG4,GPM6A,CACFD1,SYNPO,MYT1,ODF2,PGAM2,PLCD1,EPN1,PTPRG,ZFHX4,NEK11,SMTN,MAPK8IP3,WSCD1,PCDHGB6,ATP13A2,AP4E1,TK2,ICAM5,TRPC1,TRPC3,KCNK12,ZIC3,SLC30A3" Drug ctd:D010830 Physostigmine CTD 1.86E-03 1.00E+00 1.18E-02 1.34E-01 9 20 "ACHE,APP,CHRNA4,CHRNB2,DRD1,GFAP,MAP2,NTRK2,SYP" Drug CID000023305 2-methylindoline Stitch 1.86E-03 1.00E+00 1.18E-02 1.34E-01 9 20 "CHGA,CHGB,SV2A,GNAS,SCG3,PCSK5,SCG5,SYN2,SCG2" Drug CID000228398 N-ethylglutamine Stitch 1.86E-03 1.00E+00 1.18E-02 1.34E-01 9 20 "BOC,GLS,GLUL,GRIK1,MAG,NOVA2,SLC1A2,SLC1A3,ADHFE1" Drug ctd:D001418 Baclofen CTD 1.86E-03 1.00E+00 1.18E-02 1.34E-01 9 20 "GABBR1,GABRB1,MAOB,PDYN,PENK,MAPK3,RYR1,TAC1,SCG2" Drug CID000004593 olprinone Stitch 1.86E-03 1.00E+00 1.18E-02 1.34E-01 9 20 "ADRB2,ARHGDIG,ALDH7A1,EDN1,TNFAIP8L3,PDE2A,PDE3A,PDE3B,PDIA2" Drug 7062_UP GW8510; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "ACTN1,ALCAM,SRPX,KCNAB2,APOC1,KIF1A,BMP7,CA4,CAMK2B,CAMK2G,RHBDL1,CNTFR,SLC4A7,CRY2,CSF1,CD320,F5,FHL1,PDLIM5,HBS1L,GALC,ERAP1,USP19,GLYR1,GNAS,NR3C1,LYRM9,NF1,NPR2,SLC25A23,MTRF1L,PTPA,PEX5,PPP1R9A,WDTC1,IQSEC2,ST5,ROBO3,TCF7,ZMAT3,UPF3A,GDPD5,SEMA3B,URM1,KCNAB1,SSPN" Drug 6544_UP 5155877; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "MTUS1,C1QTNF1,KCNAB2,SEMA4G,PDXK,CASK,ARRB2,ATM,ADGRB2,CCNT1,LARGE1,QKI,PICK1,OSBPL3,CDON,CNNM1,SORBS3,IRAK4,TNK2,PIPOX,SORBS1,PRELID3A,TRAF3IP2,ERAP1,GPER1,MUM1,SHISAL1,MAPT,ODF2,PIK3R1,CCSER2,GON4L,C1orf54,RPS6KA2,BCAN,LIMCH1,ERC1,ZBTB43,MAPK8IP3,JMJD6,SYT1,SYT5,KAZN,WWC1,TBCEL,EVI5" Drug 2873_DN Imipenem [74431-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "SEMA6A,APOC1,ATM,CFLAR,BMP7,SCAPER,CBR1,SOCS6,ARMC8,PDE4DIP,ARHGEF4,PPP6R2,DAPK3,B3GAT3,DTNA,HIPK3,SORBS3,VPS13B,FGFR1,FAM49B,CACFD1,MAP4K5,HSD17B1,IL6ST,KCNH2,MBD1,MPP2,GIT1,PLXNB1,MBOAT7,CNNM2,TMEM231,SLC25A36,CLIP1,SEC14L1,FNDC3A,SLC22A4,WDTC1,MAPK8IP3,ASTN2,TBL1X,ZMYND8,UBE3A,REEP1,EMSY,SEMA3B" Drug 5442_DN Trifluoperazine dihydrochloride [440-17-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "APBB2,APP,ARRB1,PDE8B,MARK4,GYG2,BTRC,RAB28,HOMER3,GIT2,TRAPPC9,DNM2,EFNA3,EIF4G2,VPS13B,KAT8,ZNF589,SEMA4D,GART,MALT1,GLYR1,HNMT,JAK2,MIA2,MPP2,CNOT4,SLC11A2,PDE3B,MAPK8,PRODH,PEX5,CEP97,GTDC1,FOXRED2,MAPKBP1,RBM34,CEP68,SLC44A1,ZKSCAN5,VGF,LMF1,KCNK12,XRCC4,ZNF45,FTSJ1,RNF170" Drug 23_UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "NDRG3,ALAD,BIN1,GYG2,RAB29,ENTPD6,UBE2L6,CHN1,CHRM4,IFFO1,GAPVD1,EFNA3,ENO2,ARMCX1,BAIAP2,SEC23B,GPR153,FYN,RAB40B,AGBL5,KCNN1,KIF5C,L1CAM,MITF,MYO6,MYT1,NRGN,PIK3CD,SNX10,PLCD1,SEC14L1,SH3GL3,PPM1E,AMBRA1,SMARCD3,ZCCHC24,MYCBP2,ZC3H13,STXBP1,COBL,TBL1X,TMEM121,SEZ6L,TRIO,REEP1,MAP3K12" Drug 4104_DN Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "AP2A2,MTUS1,AK2,PLA2G6,CDC42BPA,PKP4,APOC1,CFLAR,SPAG9,CCNT1,CDC27,TPP1,GREB1,GIT2,EIF4G1,FGFR1,CRCP,GLYR1,GNAS,RASSF8,DHX35,IL6ST,INPP5B,MAP4,NEK1,NUMA1,ZSCAN32,RNASEL,TCP11L1,PPP4R3A,COA1,PRRC2C,CAMSAP2,TBL1X,EHBP1,PSD3,TMPO,KAT6B,CABIN1,CADM1,UBTF,VGF,WNK1,PRDM2,EVI5,KAT6A" Drug 2292_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "CDC42BPA,APC,APOC1,PPFIA3,CDK13,MARK4,CFLAR,QKI,HOMER3,PUM1,HP1BP3,DNM1,SORBS3,EIF5,ING4,LRRC23,ZNF589,PRELID3A,GNG4,CNTRL,NR3C1,ACOT7,IL6ST,INPP5B,NASP,PLXNB1,PRPH,SLC25A36,RNASEL,ZNF821,SH3BP2,ZNF365,FAM214B,BTBD7,EMC1,POGZ,SS18,ST5,ELOVL4,ASTN2,TK2,TMPO,MICAL1,WNK1,GDPD5,RNF170" Drug 2580_UP Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "ACTN2,NDRG2,MTUS1,AMH,CDC42BPA,ATP1A2,ATP1A3,CHGA,CHRNA4,ZFYVE9,NMT2,STOML1,COL9A3,CSF1,CSNK1E,SUSD5,ABCC9,USH1C,EDNRA,EGFR,CDKL3,ABCA8,FGF12,FGFR3,ATP2C1,ADAM28,SLC2A6,MAPT,MMP16,NNAT,DUSP26,PDZRN4,PPP5C,RGS4,SYNDIG1,SCN2B,SGK1,SLN,IZUMO4,CAND2,SPTB,SYT5,TMOD1,PARD3,TRPC1,ZBTB38" Drug 6513_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "AK2,GAS7,PLA2G4C,ADAM23,CFLAR,SLC16A4,CLGN,CHRNA4,HOMER3,IFFO1,GREB1,SPOCK2,BRINP1,DTNA,FHL1,AGAP2,GCNT2,GPR162,GNAO1,FERMT2,GRIN2C,SLC2A6,ATXN2L,TJAP1,MBD1,NEFM,PDE1C,MTRF1L,RAD52,TRIM68,MRAS,PPP4R3A,SNAP25,HECW1,SMG6,TRIM2,PCDHGA10,DOCK9,PSD3,SLC44A1,KCTD2,TRPC3,NSD2,SLC30A3,PLSCR4,JPH3" Drug 7176_DN Trifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "SERPINA3,OGT,SHROOM2,EIF4G3,BCL2L2,ARHGEF7,CDC27,LARGE1,FOXN3,TMEM184B,IQCK,CREM,SOCS5,CTH,PPP6R2,B3GAT3,E2F5,TNK2,MFSD10,ERBB2,RACK1,FGFR1,EFCAB2,PSRC1,GPD2,MAP4,MEIS1,NRGN,CCSER2,TNPO2,MED1,TMEM104,CEP97,GTDC1,FAM192A,ITSN1,RAB3GAP1,CDK5RAP2,WDTC1,PRRC2C,TRIM2,TRIO,RPRM,VAV1,LMF1,MAP3K12" Drug 1207_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "ASIC1,ZBTB10,STX16,N4BP2L1,KIF1A,BACH1,IL33,KRIT1,CPS1,AKAP12,ABCG1,VCAN,EXOG,SGK2,ING4,C1orf61,FAM49B,NCKAP1,ERAP1,LILRB4,TDRKH,STON1,DIDO1,ICA1,NOVA1,OPCML,RETREG1,PTHLH,SUPT20H,ZFP30,FERMT1,DOCK10,ST6GAL1,SLC1A7,LIMS2,KDM4D,TSNAXIP1,PBLD,POGZ,COLGALT2,TCF4,PCDHGA10,THRA,REEP1,EMSY,PLSCR4" Drug 602_UP cyclosporine A; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "MTUS1,C1QTNF3,SEMA4G,CHRD,SLC4A4,MTMR3,HAP1,PICK1,IFFO1,RIMS2,CYBB,DRP2,SUGP2,ELN,KCNMB2,ERCC2,OLFM1,TRMO,NSG1,GAB1,DENND2A,GRIA4,SOX21,MAN1B1,KIF2A,KIF5A,MMP17,CNOT4,NTRK3,CEP41,MASP1,SUSD4,BSDC1,ARHGEF10L,KIF16B,SLC22A4,RIMS1,SPTB,TROVE2,SEZ6L,TMPRSS5,CADM1,FLRT1,KCNAB1,HRASLS,CAMK1G" Drug 1525_UP Chlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.87E-03 1.00E+00 1.19E-02 1.35E-01 46 192 "ADRA1B,MRTFA,PRX,N4BP2L1,CFLAR,MTMR3,BAIAP3,CAMK2B,ARHGEF1,CHRNB2,LHX2,CSF1,ELMO1,MFAP3L,ZNF589,FGF13,AMOTL2,CAMSAP1,FHL1,POLL,ELOVL5,KCNJ4,MIA2,MITF,ZNF862,NOVA2,NPPA,NPR2,NTRK2,CDK18,PDE4A,PRODH,FAM120C,ZFHX4,RPS20,SYBU,ZNF365,RAB3GAP1,SLN,RBM34,ZSWIM8,ARHGAP26,PCDHGA1,CDK20,VLDLR,MARCH8" Drug CID000005118 AC1L1JND Stitch 1.88E-03 1.00E+00 1.19E-02 1.36E-01 23 79 "ADCY6,ADORA2A,ADRA1B,NGB,CHRM1,DRD1,ENO2,PPP1R1B,GAD1,GAD2,GRIN1,GRIN2C,GRIN2D,GSN,HTR2A,KCNJ3,KCNJ5,KCNJ9,RGS3,MLST8,NTSR2,PORCN,DPYSL5" Drug 6872_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 1.90E-03 1.00E+00 1.20E-02 1.37E-01 45 187 "NDRG2,APOC1,ADAM15,BTRC,CA12,EPS15L1,LRIG1,GREB1,TBC1D5,SMG7,DTNA,E2F5,FCF1,RASGRP1,APH1A,EGR3,KIAA1109,BAIAP2,KCNMB4,HSF2,JAK2,KCNF1,KIF5C,LIG4,LSS,CNOT4,PIK3R1,NLE1,PLEC,PEX5,ATG16L1,RET,GSTCD,FOXRED2,SGK1,FNDC3A,NXT2,ASTN2,DMXL2,TRIM2,TRIO,HIRA,EMSY,SCG2,NUP214" Drug 953_UP radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.90E-03 1.00E+00 1.20E-02 1.37E-01 45 187 "NDRG2,OSBPL1A,MPDZ,CFLAR,SCARB1,FOXN3,VAX2,ARMC8,AKAP5,CSNK1E,PDE4DIP,FAM169A,CTH,EDRF1,ARHGAP24,DBT,RCAN1,DTNA,DUSP9,FHL1,ATP2C1,B4GALNT1,GRB10,NR3C1,JAK2,MAOB,NAP1L2,KLK6,ZSCAN2,MORC4,TCP11L1,FOXRED2,ATXN1,HSPA4L,SGK1,SH3BGR,ZFP30,FBXO11,PREX2,SLC2A5,TROVE2,ATP11A,FBXW11,VLDLR,FXR1" Drug 4163_UP Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.90E-03 1.00E+00 1.20E-02 1.37E-01 45 187 "BIN1,N4BP2L1,FGF17,ENTPD2,ADGRG1,TAOK2,BRINP1,SPOCK3,EDIL3,ST8SIA3,EDN1,EGFR,ERBB4,CEND1,F5,CORO2B,AGAP2,GAD1,ATP8A2,GFER,RND1,GPR22,GRIA4,KCNMA1,LMO1,MID1,OPCML,KCNK10,PALM,PTPRB,KLHL11,TMEM206,SLC1A3,KIF21B,MLC1,ARC,PCDHGA10,RALYL,SLC35G2,SPX,TNS1,SEZ6L,ZIC3,SEMA3B,AP3B2" Drug ctd:D015127 "9,10-Dimethyl-1,2-benzanthracene" CTD 1.90E-03 1.00E+00 1.20E-02 1.37E-01 200 1052 "ACTN1,NDRG2,ADCY2,ADCY5,ADD3,HHATL,ADORA2A,HACE1,OSBPL1A,SPARCL1,ANK3,PPFIA4,APAF1,APOC1,MADD,CASK,RGS20,ASCL1,MARCH3,ASPA,CHRD,ATM,MYOM1,KIF1A,MPDZ,BID,CFLAR,C1QC,IL33,CACNA2D1,CALB1,CAMK2B,CAPN3,KYAT1,SCARB1,SYNGR3,CFL2,FOXN3,ARHGAP22,SLIT2,NRXN1,CLU,QKI,HECTD1,CNN3,AKAP6,GDA,TENM4,PDE4DIP,CST3,GPSM1,ARHGAP32,FRMPD4,DBI,AIF1L,LYPD1,KIF19,DLG2,DNAJB6,EDNRB,EEF1D,LPAR6,EIF4G2,CERCAM,BSCL2,GPHN,TMEM132C,EFEMP1,RACK1,FGF13,SYNCRIP,FOXO3,FLNC,ATP13A4,FLT1,DPYSL4,PDLIM5,ARFGAP2,CAMKK2,CGREF1,NSG1,TPPP3,ABLIM2,AHCYL1,HIGD1B,GATM,TUBA8,SESN1,MMADHC,GGT7,GHR,PPARGC1A,MALT1,LYVE1,HPGDS,GLS,OS9,KCNMB4,RAB40B,GPD1,RAPGEF4,GRB10,GSN,GYG1,HBA1,HNRNPK,HP,IDH3B,IGF1,IL12A,TUBB2B,KHK,KIT,STMN1,SMAD1,MAT2A,AQP11,MEIS2,KITLG,MN1,DBNL,CCDC80,MYH7,HNRNPM,RCOR2,NELL1,NFE2L2,NFIX,NPTX1,NUCB2,SETD4,OGG1,PDE1C,PENK,TMIE,PLCL1,FXYD1,PPP2R2B,PKIA,PRKCB,PSMD13,PTPRD,PPP2R3C,IQSEC3,RDX,SETD5,RXRG,MAPK12,HOGA1,PUF60,SCAF8,SH3BGR,FBXO11,SLC1A3,SLC6A8,SLC12A2,CPEB4,NAXD,SLN,GKAP1,LIMCH1,MYCBP2,SPP1,ITPRID2,MPRIP,VPS13A,PDLIM2,DOCK9,OBSL1,ARHGAP9,DICER1,AKTIP,THRA,ZFP91,TMPO,PARD3,KAT6B,TNS1,PIK3R5,TP53BP2,TPM1,TPM3,ZNF384,SSBP2,UBE2H,VGF,VLDLR,VSNL1,SLC13A3,ZNF32,SH3GLB2,CSDE1,WNK2,GOPC,RTN4,ACTR3B,FXR1,NETO2,RNF146,CBLN2" Drug 3808_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.92E-03 1.00E+00 1.22E-02 1.38E-01 44 182 "CDC7,PDXK,ARRB2,ST3GAL5,CA12,CAMK2G,LHX2,ARHGAP32,TBC1D5,RIMS3,DLG3,ABCC5,EFNA3,FAM13A,PLEKHO1,SCARA3,PSRC1,GPER1,SHISAL1,ITPKB,JAK2,ZNF862,RAB3A,SH3TC2,ATG16L1,MAP6D1,FAM102A,DOCK10,ST6GAL1,ANKRD6,LIMS2,COA1,PDZD2,PHLDB1,TRIM2,GPR161,HEY1,CBX5,REEP1,MPPE1,MVB12B,PLSCR4,FZD3,PHTF2" Drug 1160_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.92E-03 1.00E+00 1.22E-02 1.38E-01 44 182 "AP2A2,PLA2G6,PDE8B,ATP6V0A1,CFLAR,ST3GAL5,SULT4A1,CREM,KIAA0513,ZNF337,DBT,FAM13A,VPS13B,EPB41L2,ERBB2,CAP2,HBS1L,GLYR1,TAGLN3,KCNK10,PDE4B,CCSER2,NECAB2,MBOAT7,PRKAB2,PRKACB,KLK6,PTAFR,RGS10,FBXW7,ASIC4,RASA3,HSPA4L,ITSN1,PEX26,DNMBP,TBL1X,SLC44A1,TNNT1,TNS1,TPM1,KCNAB1,PCBP4,PHTF2" Drug 3142_UP Ribavirin [36791-04-5]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.92E-03 1.00E+00 1.22E-02 1.38E-01 44 182 "ABHD6,ADORA3,BCAS1,ASPH,MPDZ,BMP7,CACNB4,CACNA2D2,TAOK2,PICK1,CREB5,RIPOR2,DTNA,SIDT2,CEND1,FGR,C1orf61,GFER,GRIK5,GRM7,VSIG4,KCNMA1,OMG,SNTG1,PBX1,CAMKV,FSD1,CEP41,MAPK10,PTPRB,MARCH1,FOXRED2,SLC1A3,PREX2,SLC11A1,SLN,SNAP25,SNCA,ATP10B,ACSBG1,TMOD1,VIPR2,ZBTB16,ADAMTS9" Drug CID000007333 "1,3-di-o-tolylguanidine" Stitch 1.93E-03 1.00E+00 1.22E-02 1.39E-01 19 61 "KDM5D,CACNA1E,CCKBR,DNM1,DNM2,DRD1,DNM1L,ZMYND10,DNER,MCHR1,GRIN2C,GRIN2D,KCNJ3,KITLG,NPY,OPRL1,RBBP8,SYN2,SSPN" Drug CID005311317 AC1NSKF2 Stitch 1.93E-03 1.00E+00 1.22E-02 1.39E-01 19 61 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,ADORA3,ENTPD2,MAP4K4,OSBPL3,SLC29A4,GART,SESN1,CIT,EPN1,PYGM,TMEM132D,STX1A,ZMAT3,ST8SIA2" Drug CID000003340 fenoldopam Stitch 1.94E-03 1.00E+00 1.23E-02 1.39E-01 21 70 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,ALDH7A1,CACNA2D1,DRD1,EDNRA,EDNRB,PPP1R1B,GNAS,GRK4,CIT,NPPA,PDE3A,PLCB2,PLCB1" Drug 4164_UP Thioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.94E-03 1.00E+00 1.23E-02 1.40E-01 43 177 "ADORA2A,CDC14B,N4BP2L1,CALB1,NCOR2,CRYM,RUSC2,CDON,DSCAM,EPHB1,ERBB2,EFS,F5,FLT1,OGA,GABRA2,DISC1,SRCAP,RND1,GRIK2,IFI16,IL6R,ITGAM,MOBP,NCAM1,NEFM,ACSM5,RPS6KA2,ATXN1,SCG5,ST6GAL1,CNKSR2,SLC6A9,SLC11A1,ATP10B,MAPK8IP3,AJAP1,TRIM2,PHF24,LAT2,PRDM2,SEMA3B,NAV2" Drug 3060_UP Digoxigenin [1672-46-4]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.94E-03 1.00E+00 1.23E-02 1.40E-01 43 177 "CLK4,SLC12A5,CDC14B,PROM1,CACNB4,THSD7A,RUNX1T1,CBFA2T2,CDH10,NRG2,CREM,CSF1,CTNND2,EIF1,APC2,HPCAL4,IP6K2,PRELID3A,ALDH1L1,RND1,GNAL,GRM1,BTN2A1,IL6ST,MAG,NFYA,NNAT,CNOT4,PDE4B,ENPP2,CNNM2,PTX3,MYH14,SELL,SFPQ,PPM1E,SLC1A7,SMTN,ZNF430,BTBD7,ATF7IP,SLCO1A2,CHST8" Drug 1159_UP 17-AAG; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.96E-03 1.00E+00 1.24E-02 1.41E-01 42 172 "NDRG3,NDRG2,GRAMD1B,MTUS1,CFLAR,ST3GAL5,GYG2,CD86,RAB28,RCHY1,CREM,SIPA1L1,EDRF1,KIAA0753,RCAN1,FAM13A,MBNL2,VPS13B,F5,KIAA1109,FHL1,CAP2,ATP2C1,OGA,HSP90AA1,MPP2,PDE4B,PDE4D,NECAB2,MBOAT7,PRKACB,ZSCAN32,HSPA4L,ITSN1,ZC3H13,SPTAN1,SRPK2,NPDC1,MPPE1,PHTF2,FXR1,SENP7" Drug CID000003918 levo-dromoran tartrate Stitch 1.97E-03 1.00E+00 1.24E-02 1.41E-01 27 98 "ADCY2,ADCY5,ADCY6,ADCY8,DMPK,LYVE1,GNAS,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,TNFAIP8L3,OPCML,OPRL1,PDYN,PENK,AP1AR" Drug CID000002832 NSC3096 Stitch 1.97E-03 1.00E+00 1.24E-02 1.41E-01 27 98 "CDK13,BLM,CHN1,GPSM1,DBN1,DCTN1,TUBD1,TUBB3,TUBB4A,ACTL6B,TUBA8,TUBA1C,NR3C1,HSP90AA1,TUBB2B,NUMA1,CNTN3,CDK14,ABCB1,PTCH1,PTK2,PTPRN2,FBXW7,ACTR6,TUBB2A,TUBB1,TUBA1A" Drug CID000002360 ODAP Stitch 1.97E-03 1.00E+00 1.24E-02 1.41E-01 16 48 "CA4,FOLH1,GGT5,POLL,GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRM3,IL6ST,MID1,NDUFA5,NDUFS7" Drug CID000466959 Hb H Stitch 1.97E-03 1.00E+00 1.24E-02 1.41E-01 16 48 "ADAR,KIDINS220,BCS1L,NGB,LRBA,CS,DLG3,EPB41,TUBB3,FOXG1,GNAS,PTPN5,HBA1,PPP1R1A,SOX8,SCN2A" Drug CID000004916 procaterol Stitch 1.97E-03 1.00E+00 1.24E-02 1.41E-01 16 48 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,ARHGDIG,ALDH7A1,GALR1,GNAO1,GNAS,ITGAM,NEUROD1,PTPRN2,PDIA2" Drug CID000328776 AC1L73CW Stitch 2.01E-03 1.00E+00 1.27E-02 1.44E-01 24 84 "PDE8B,RGN,GAP43,GNAO1,NR3C1,TNFAIP8L3,HNMT,SLC11A2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PIK3R1,MAPK3,MAPK4,MAPK7,MAPK8,RGL1,STMN4" Drug 2579_DN Folinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RALGAPA1,ASIC1,MRTFA,BIN1,AMT,SLC4A4,CACNA1I,CHN2,TAOK2,NMT2,SPATA2,ST8SIA3,EDNRB,PLEKHA1,ELN,LRRC23,DLC1,FGFR1,FHL1,GAD2,GPM6B,GRM7,MOBP,GIT1,NTRK2,PDE4A,SLC25A23,MAPK7,LRRC49,PTAFR,PEX5,FOXRED2,SBF1,SH3BP2,AMBRA1,EPN2,ZKSCAN3,IQCE,TCF7L2,OBSL1,THRA,CDK20,TPM3,LMF1,REEP1,MAP3K12,KCNAB1" Drug 1579_UP Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "MRTFA,APAF1,BMP7,CAMK2B,CAST,CHRNB2,SLC24A2,MAP4K4,AKAP7,SLC4A7,CSF1,RIMS3,DAPK1,C2CD2L,TRAPPC9,ANKRD46,F3,ZNF589,FLNC,ATP2C1,PRRC2B,KCNN1,KHK,MYT1,NEFH,NPPA,NTRK2,PDE1C,PLCB2,PPP2R2B,MAPK3,PTK2,CCDC40,RLBP1,ZNF671,SAFB,SCN2B,SH3BP2,SLA,ELMO2,SMARCA4,ZC3H13,IQSEC2,OBSL1,MFF,PRDM2,SNX27" Drug 5681_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "APBB2,APOC1,APP,ARRB1,ARRB2,ATP6V0A1,CDK5R1,TAOK2,SLC4A7,ENTPD4,SIPA1L1,PDE4DIP,GPRASP1,DAPK3,DTNA,EFNA3,MRNIP,ZNF589,FGFR1,ANKFY1,EFCAB2,TRAF3IP2,GART,COPS8,GLYR1,MSL3,CNTRL,RNFT2,HNMT,INPP5B,KCNJ3,MBNL1,MDM4,ADAM22,NUMA1,SMIM7,FSD1,NEK11,RPS6KA2,SLC1A7,LIMCH1,USP33,NXT2,ELOVL4,MAP3K12,EVI5,PHTF2" Drug 5449_DN Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG3,C1QTNF3,LTBP4,PPFIA3,ARHGDIG,MARK4,SYNJ2,SCAPER,BTRC,KYAT1,MAGI1,ARHGEF6,NECTIN3,MAML1,RUSC2,DSCAM,EIF4G2,PLEKHO1,DMTN,EFEMP1,FER,FHL1,SEMA4D,KPNA5,ADAM22,ZNF862,NDUFA5,SLC11A2,MINDY2,ASAP3,SLC6A8,LIMCH1,EMC1,ERC1,TSPYL2,PLCB1,MCF2L,EXOC7,IQCE,PSD3,CHST8,AP4E1,TGFBR3,PARD3,ZFP37,MPPE1,MVB12B" Drug 3520_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "KIDINS220,AP2A2,PLA2G6,APBB2,ARRB1,PLA2G4C,MARK4,GYG2,CRLF1,B4GALT6,NMT2,SH2B1,PPP6R2,MAML1,DAPK3,RUSC2,EFNA3,EN2,LRRC23,GPR153,GAB1,NCKAP1,COPS8,TDRKH,GPR19,INPP5B,KCNH2,MID1,NEK1,NF1,NFYA,GPSM2,PRKAR1B,RGS12,ZKSCAN3,KDM4C,CAMTA2,POGZ,CEP68,PHLDB1,ARHGEF9,IQCE,CHST8,BHLHB9,ZMYND8,SPHK2,SSPN" Drug 459_UP copper(II) sulfate pentahydrate; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RBM10,APAF1,DGKD,ARNTL,BACH1,MAP7,SEPT7,CDC27,TAOK2,CLU,PCYT1B,IFFO1,CRMP1,B3GAT3,BSCL2,SMC2,OGA,TMEM8B,INPP5K,NEU3,SYNPO,AGFG1,RBPJ,KCNN1,MT1M,NELL2,CAMKV,PNMA3,CNNM2,MAPK12,ATXN2,GALNT10,SLC1A3,SLC20A2,SNAP25,MAPKBP1,EMC1,SRPK2,ANKRD12,CAMSAP2,DMXL2,ZEB1,CHST8,SPX,TRPM2,TMPRSS5,NPDC1" Drug 592_DN probucol; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "PLA2G6,BIN1,OGT,APAF1,APOC1,ARNTL,ARSE,ALDH4A1,ATM,NRP2,CFLAR,ARHGAP33,CHRM4,SLC24A2,SEC14L5,DRP2,RCAN1,SUGP2,APH1A,ZNF589,HPCAL4,GALC,GLYR1,PTPRT,NXPH3,ATXN2L,C2orf72,IGF1,STMN1,AFF1,PALM,PFKFB2,GSTCD,TMEM206,FUZ,SLA,DOK5,PHLDB1,COBL,SEMA4A,TNS2,TEX15,DAAM2,TRIO,TMPRSS5,VAV1,AAAS" Drug 3024_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADORA2A,ADRA1D,TRMT9B,AMPD3,CDK10,AZGP1,NIPBL,CPS1,OSBPL3,CTIF,EXOG,HIPK3,MRNIP,MTSS1L,KIAA1109,ZNF44,ERAP1,SEPT9,SPACA9,GRM8,SLC2A6,NCKAP1L,KCND3,SMAD1,NFYA,ODF2,SLC25A23,PLTP,LRP12,PTPA,PTN,FAM120C,RGS10,TCP11L1,SCN2B,SEC14L1,ITSN1,WDTC1,CAMSAP2,FBXW11,TCF4,TCF7L2,SYNE1,THRA,CABIN1,UBE3A,ZNF142" Drug 6519_DN Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,TRMT9B,CDC14B,PDE8B,CACNG1,CDH8,CRLF1,CHRNB2,CLU,LY86,FAM169A,DZIP3,MFAP3L,SMG7,RABGAP1L,SORBS3,MTSS1L,KAT8,CAMSAP1,GAD1,GART,IGSF1,MAPT,MIA2,NF1,NPR2,NPTX1,NUMA1,PLEC,TMEM104,FAM120C,TMEM231,C1orf54,KHDRBS2,SH3BP2,BCAN,ZNF365,SLC22A4,WDTC1,ZC3H13,SS18,CEP68,TBL1X,NSD1,AHCYL2,SSBP2,HIRA" Drug 3603_DN Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ARRB1,ASPH,ATM,BMP7,SCAPER,BTRC,ARHGAP33,SLIT2,RAB28,QKI,SLC4A7,NCOR1,ZNF337,DAPK3,HIPK3,COQ7,STX2,ZNF589,SYT17,ALDH1L1,ZNF276,MSL3,TDRKH,CNTRL,GSN,MUM1,IL6ST,MAP4,CNOT4,PPP5C,PTHLH,GSTCD,TCP11L1,RPH3A,KDM4C,THSD1,ASTN2,TCF7,PCDHA6,AHCYL2,AP4E1,HEY1,TK2,PLPPR2,GDPD5,ZNF248,LAS1L" Drug 7551_DN vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "PPFIA3,ASPH,CA12,CAMK2B,KYAT1,JAM2,QKI,HOMER3,SLC4A7,CRY2,NCOR2,ABCG1,PDE4DIP,DAPK3,DTNA,SORBS3,CAMSAP1,ATP2C1,MPP6,OGA,KCNMB4,GNG4,NXPH3,KHK,LSS,MATK,MMP16,MSI1,NACA,LRP12,PACSIN1,RIPOR1,RGS12,TCP11L1,RPS6KA2,SEC14L1,FBXO11,CCDC88A,RCOR3,SNCA,SP4,PBLD,ANKRD12,TRIM2,TNS2,RPRM,ZNF45" Drug 6056_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "MTUS1,KIAA1324,MARK4,LDB2,CDH2,QKI,NCOR2,IPCEF1,SPOCK2,SMG7,SPOCK3,SGK2,MBNL2,ELAVL3,NCALD,CEND1,PTK2B,ST3GAL6,SORBS1,KHDRBS3,GAP43,ALDH1L1,C1QL1,GPM6A,GPM6B,SOX21,HTR2A,KCNB1,PFKFB2,PRKCB,PTAFR,PTPRN2,FAM120C,ZMAT4,CARF,SH3BP2,BCAN,RPH3A,LIMS2,KANSL3,SLC11A1,ATP11A,TBCEL,TK2,HEY2,TRH,FLRT2" Drug 1534_DN Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASPHD1,NDRG2,APBB2,CDK10,KIF1A,ADAM15,GYG2,CACNA1D,VAX2,SULT4A1,CREM,DBT,TMCC2,DNM1,RCAN1,DTNA,SORBS3,CDKL3,VPS26C,PDLIM5,CNTRL,KCNJ3,NFYA,NOS1,OGG1,PDE3B,STRN3,PRKACB,MAPK8,WDR25,RGS10,ROM1,NEK11,ZNF331,SBF1,ZNF821,ANKRD6,PPP4R3A,UNC5B,LHPP,PLCB1,ARC,TCF7L2,TNS2,PCDHA6,XRCC4,SPHK2" Drug 1904_DN Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADRB2,PLA2G6,PPFIA1,ARHGAP5,MARK4,BCL7A,BID,HIP1R,CHRNB2,ARMC8,SOCS5,SIRPA,KIAA0753,MAMLD1,SEZ6L2,SORBS3,PCOLCE2,DCTN4,EPB41L2,BAIAP2,AMOTL2,WASF3,DBF4,PRRC2B,HAS2,LAMP2,MKLN1,NEK1,PIK3CD,MAPK3,C1orf109,CEP97,MSANTD2,ABLIM3,SLC2A5,SLC12A2,GANAB,ZEB1,HEY1,CBX5,KCTD2,R3HDM1,RBFOX2,TRIO,PLPPR2,SPHK2,NAV3" Drug 5645_DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AP2A2,GAS7,AQP4,MARK4,CAMK2G,CDC42,CLGN,CRLF1,STOML1,RCHY1,SH2B1,KBTBD11,SORBS3,LRRC23,STX2,NCALD,ZNF589,FGFR1,FHL1,OGA,ALDH1L1,TXNL4A,KLF12,MMP16,ZNF862,EPN1,SAMD9,PLPPR1,RAB3IL1,CEP97,RGS10,KCTD17,ASAP3,RPH3A,WDTC1,ZHX3,ELOVL4,PLCB1,ATP11A,SZT2,CRTC1,RUNDC3B,VAV1,VIPR2,SLC17A7,EPM2A,SSPN" Drug 4970_DN Hydrochlorothiazide [58-93-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADORA2A,ADRA1D,BIN1,NCOA1,KIF1A,CACNA1D,CAMK2G,KYAT1,QKI,CSNK1E,PDE4DIP,ARHGEF4,JAKMIP2,DRD1,EFNA3,CELSR3,EML1,SCML2,FGF12,C1orf61,EFCAB2,PRELID3A,ATXN2L,KIF5C,LYRM9,ZNF862,NTRK2,NUMA1,NKAIN1,RAB3A,RAB3IL1,NEK11,SUPT20H,PPP1R9A,ZCCHC24,ARHGAP26,SPTAN1,CDK19,ZBTB43,TROVE2,MAPK8IP3,EXOC7,DICER1,TMEM121,TMOD1,TRPC1,ST7" Drug 1430_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASIC1,CDC14B,CAST,ZFYVE9,CLCN3,AATK,PPP1R16B,SIRPA,C2CD2L,IRAK4,MRNIP,KIAA1109,FGR,FOXM1,GAA,PRRC2B,FAM107A,NACA,OCRL,PALM,ENPP2,PLCD1,MAPK3,CNNM2,DEF8,TMEM260,C1orf54,CCDC25,ZNF671,FAM214B,ELMO2,SLN,MAPKBP1,TNIK,FAM208A,MGRN1,EHBP1,TCF4,THRA,KAT6B,TNS1,PLPPR2,TRIM9,VPS35L,SNX27,ZNF248,AAAS" Drug 2712_DN Sulfameter [651-06-9]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASIC1,APAF1,APBB2,PPP4R4,ARRB1,BACH1,HOMER3,CLOCK,CREM,SH2B1,OSBPL3,VCAN,DOCK4,DTNA,CELSR3,ING4,ZNF589,GNG4,LILRA2,GPR22,MAP4,NF1,OCRL,OGG1,PCDH9,PLTP,ZDHHC14,FBXW7,CLIP1,SH3BP2,SLC11A1,KDM4B,SS18,CAMSAP2,KIAA1107,WWC1,CRTC1,TK2,TMPO,TPM2,TPM3,REEP1,MAP3K12,EVI5,GDPD5,UBE3B,PHTF2" Drug 2155_DN Vitexin [3681-93-4]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,NDRG2,MRTFA,APOC1,BMP7,USP2,RIMS3,HIPK3,EFNA3,ING4,ELN,ETV1,FHL1,GAA,ZMYND11,GATM,USP19,POLL,KCNMB4,MAP4K5,GIT1,MX1,MYT1,NOS1,SLC11A2,OGG1,PLCD1,CNTLN,ZSCAN32,RAB3IL1,RAD51D,ZDHHC14,SH3BGR,PPM1E,PREX2,SLC11A1,SLC15A2,IZUMO4,TSPYL2,JMJD6,PLCB1,PDLIM2,TCF4,KCTD2,TPM1,MPPE1,PHTF2" Drug 7096_DN "ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BIN1,CFLAR,ENTPD6,KIAA1549L,HOMER3,DCAF4,ZFYVE16,ZNF589,FGFR1,BAIAP2,FHL1,TPK1,OGA,GART,CRCP,FERMT2,GUCY1A1,GUCY1B1,SLC2A6,MKLN1,NASP,NPR2,NUCB1,PAX6,PDE1C,PLCD1,POLG,PPP5C,TMEM104,RAB3A,SEC61A2,MYH14,MCMBP,SBF1,ATXN2,CCDC88A,WDTC1,TNIK,TSPYL2,NCDN,SIK3,ATP13A2,MTMR14,TK2,SMIM8,ACTR3B,AAAS" Drug 6261_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,AK2,MTMR2,CBFA2T2,PLAA,SMG7,SGSM2,DNM1,FEM1B,SIDT2,SUGP2,EGFR,EIF5,F8,GLS,MSL3,GRB10,IGSF1,MAP4,MBD1,MITF,NUCB1,PLXNB1,NKAIN1,SEC61A2,ROBO1,WLS,RXRA,NCBP3,ITSN1,FUZ,SMARCA4,RCOR3,WDTC1,SOX3,FNBP1,EMC1,ZBTB43,TROVE2,ELOVL4,FAM168A,FBXW11,TBL1X,TCF7L2,HIRA,EIF4ENIF1,MAP3K12" Drug 4729_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "FAM131A,SLC2A11,CFLAR,CACNA1D,ARHGEF1,ARHGEF2,FOXN3,HOMER3,NCOR2,EDRF1,DBN1,SMG7,PARD6A,DSCAM,MBNL2,ING4,STX2,NCALD,AFF2,GAD1,SEPT9,TDRKH,MAP4K5,ATXN2L,AGFG1,IL6ST,KCNF1,KCNMA1,MAP4,NF1,RETREG1,STRN3,PRKAR1B,RAD52,SELL,ZNF423,TROVE2,PLCB1,TBL1X,EHBP1,DICER1,TMPO,HIRA,ZNF45,SPHK2,MAP3K12,PRDM2" Drug 2057_UP Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "TRMT9B,ZSCAN18,ALDH4A1,ATM,SLC4A4,BTRC,LARGE1,HOMER3,AKAP7,TENM4,DAPK3,DBT,LYPD1,FCF1,ELN,FGF1,FGFR1,TRMO,CINP,TRAF3IP2,GCNT2,HTATSF1,IL6ST,KHK,LIG4,CDK14,PTPA,MAPK7,PRPH,PTCH1,CCDC40,TRA2B,PPP1R9A,ST6GAL1,CDK19,THSD1,CEP68,SYT11,IQCE,TRIM2,DOCK9,ZKSCAN5,WIPF1,SH3GLB2,EVI5,KCNAB1,PHTF2" Drug 6590_UP prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADCY2,BIN1,GAS7,MADD,MTMR3,GYG2,CACNA1I,MYRF,CFAP410,MFAP3L,DTNA,ST8SIA3,EGFR,PLEKHO1,SCML2,BAIAP2,GPR153,CSPG5,GLS,CNTRL,GRB10,MAP4K5,NXPH3,MAN2A2,ADAM22,MYO7A,ZNF862,CNOT4,PENK,SNRK,FAM120C,ZFHX4,NEK11,RPS6KA2,FERMT1,EPN2,SLC9A5,RCOR3,ZCCHC24,ATP10B,PCDHA6,CHST8,HEY1,TMOD1,TPM1,RPRM,LAT2" Drug 2489_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AP2A2,MTUS1,C1QTNF3,BIN1,GAS7,APOC1,CDK10,ASPH,SCAPER,CACNA1A,RAB33A,NMT2,HOMER3,CNTN1,ABCG1,SLITRK5,ING4,TUBD1,PIPOX,PTK2B,ZNF44,GART,GLS,GPR19,IL11RA,SLC11A2,SETD4,PENK,CCSER2,PLCD1,SLC25A23,PILRA,DEF8,CNTLN,PTN,RAD52,SEC14L1,SLC11A1,TROVE2,TCF7L2,CRTC1,TPM1,ELP5,CLIP2,SYNC,ACTR3B,SENP7" Drug 3384_UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,ADRA1D,CDC42BPA,N4BP2L1,ATP6V0A1,CACNA1I,LDLRAD4,CFAP410,HIP1R,INA,NEURL1,CBARP,ZFYVE9,SULT4A1,CPS1,RASSF2,SRGAP3,C3orf18,MTSS1L,FGFR3,NEU3,C1QL1,NR3C1,TJAP1,LIFR,MYCN,ZNF862,NNAT,NPPA,TMOD2,EPN1,CEP41,MAPK8,RASGRF1,ZDHHC14,RGS10,SYNDIG1,ST6GAL1,KDM4B,TSNAXIP1,PEG10,SYT11,JMJD6,ROBO3,TCF4,OSBP2,KCNAB1" Drug 6362_DN Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BRAP,APLP1,ATP2A2,ADAM23,CFLAR,LDLRAD4,QKI,VCAN,TOX,RUSC2,DNM2,EDNRA,SUGP2,MRNIP,HSD17B14,BAIAP2,TRAF3IP2,INPP5K,GPER1,GRIK5,GUCY1A1,HSF2,KIF5C,MX1,SLC11A2,PC,PLCD1,RC3H2,MAPK3,PEX5,SEC61A2,ZNF671,ASAP3,AMBRA1,SMARCA4,TMCC1,BEX1,MAPK8IP3,ASTN2,SMG6,WSCD1,PLPPR2,TRIM9,NDRG4,SH3GLB2,DPF3,RNF146" Drug 6929_DN 2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BRAP,KIDINS220,OSBPL1A,STX16,BMP7,C5,SOCS5,PDE4DIP,GIT2,C2CD2L,DCTN4,FAM49B,SRCAP,CRCP,GRM8,BTN2A1,RNFT2,ATXN2L,HSF2,IPO5,MAP4,NCAM2,NPR2,SETD4,TNPO2,POLG,GTDC1,RGS3,ZFP30,FUZ,ZKSCAN3,ERC1,PBLD,TROVE2,ITPRID2,ANKRD12,SATB2,TCF7L2,BEX4,RBFOX2,TRIO,TRPC1,HIRA,NSD2,XRCC4,MARCH8,ZNF248" Drug 1328_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABR,ADORA3,APP,STX16,N4BP2L1,RIPK1,CFLAR,SCAPER,CAPN3,CLCN4,QKI,SLITRK5,KIAA0586,DTNA,FRY,RBM12,CELSR3,ERCC2,PDLIM5,GLS,VSIG4,VWA5A,NF1,NFYA,PDE4B,MAPK3,SAMD9,SIDT1,C1orf109,CEP97,RAD51D,RGS10,SH3BP2,AMBRA1,RAB3GAP1,KIF1B,TAB2,NXT2,PJA1,TNNT1,NR2C2,XRCC4,ZNF142,LAMP5,MPPE1,ACTR3B,RNF146" Drug 7431_DN Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BRAP,APOC1,PPFIA3,CDK10,ADAM15,CFLAR,VAX2,ABCG1,PDE4DIP,PPP6R2,KIAA0586,C2CD2L,RABGAP1L,TRAPPC9,RCAN1,DTNA,RBM12,SUGP2,SORBS3,TNK2,BAIAP2,CELF1,INPP5K,SRCAP,GLS,CNTRL,LSS,NFYA,PMP22,RAD51D,RALGDS,GTDC1,RGS10,TCP11L1,FUZ,BTBD7,WDTC1,CDK19,MCF2L,AGTPBP1,ZNF74,SPHK2,REEP1,SEMA3B,MPPE1,ST7,UBE3B" Drug 2150_DN Harmane hydrochloride [21655-84-5]; Down 200; 18.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,AP2A2,GAS7,PPP4R4,MARK4,ATP6V0A1,SYNJ2,SOCS6,CLCN4,OSBPL3,DGKG,ELN,FGFR1,AGAP2,GAA,GAB1,GABRA4,SEPT9,WASF3,SRCAP,LILRA2,LSS,MAP4,P2RY1,PTPA,PTCH1,PEX5,MYH14,GSTCD,ITSN1,AMBRA1,SLC11A1,KDM4B,WDTC1,IZUMO4,NCDN,DNMBP,TCF4,TCF7L2,CHST8,TMOD1,TNNT1,RBFOX2,TPM1,HIRA,URM1,PHTF2" Drug 2319_UP Phenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADORA2A,AMPH,APBA2,EPB41L5,ARSE,CADM3,MTMR3,GYG2,ZFYVE9,AKAP7,SLC4A7,RCHY1,ATRNL1,PPP1R16B,HS3ST2,SHANK1,SGK2,EPHB1,PTK2B,OLFM1,FGFR1,HPCAL4,GAB1,GABRA2,GUCY1A2,HNMT,HTR5A,ICA1,KCNB1,KCNC1,MOBP,EPN1,PPARA,GDPD2,RAB3IL1,CCDC40,C1orf54,KHDRBS2,ZFHX4,STUM,FAIM2,ZNF423,TCF4,HIF3A,TRPM2,SLC30A3,GJC2" Drug 1828_UP Naproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "MRTFA,BIN1,SHROOM2,ADGRB2,MPDZ,CFLAR,SYNJ1,FOXN3,NRXN3,ELMO1,EDNRA,FGF1,CSPG5,ERAP1,GNAL,GNG4,GRIK5,CACFD1,BACH2,IL6ST,SCAMP5,NAP1L3,CNOT4,SLC11A2,MAPK8,CNNM2,SIDT1,RAB3A,NUDT11,STUM,SH3GL3,SLC1A7,PEX26,CCDC88A,WDTC1,FNBP1,SPTB,CAMTA2,MAPK8IP3,SYN2,ZNF34,BEX4,CABIN1,SF1,ZNF74,SPHK2,AAAS" Drug 5451_DN Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADCY6,PLA2G6,CDC14B,CACNB2,MAGI1,CRY2,SIPA1L1,PDE4DIP,CNTNAP2,ZNF804A,RUSC2,DSCAM,PLXNC1,DENND4A,ANKMY1,ZNF589,FHL1,DISC1,INPP5K,AHDC1,ELOVL5,JAK2,KHK,NDUFA5,NF1,SERPINE2,PTHLH,RAD52,CARF,EMID1,SH3BP2,SLC1A7,SMTN,BTBD7,SLC20A2,SPATA7,KDM4C,PHLDB1,VAMP1,MCF2L,KIAA0930,TRPC1,PLPPR2,ZFP37,ZBTB14,WNK1,EMSY" Drug 5515_DN Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RBM10,ABHD6,AP1B1,BCAR3,APC,MICAL2,USP6NL,KIAA0586,GIT2,SPATA2,SMG7,EGFR,IRAK4,EPB41L1,EPB41L2,COQ7,ANKMY1,POLR1B,FGFR1,DIDO1,NR3C1,CIT,MAP4K5,HSD17B1,IL6ST,VWA5A,MAPT,TM6SF1,NF1,SLC11A2,OXTR,PRKAR1B,SYTL2,PTPN13,RAB3A,MSANTD2,RGS3,PPP4R3A,BTBD7,INTS9,DNMBP,TRIM2,CHST8,HIRA,XRCC4,NAV2,SSPN" Drug 7542_DN Ald1.1-H_000455; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,AK2,SEMA6A,CDC42BPA,MARK4,ATP6V0A1,BCL7A,PLEKHB1,DBN1,DBT,SMG7,SIDT2,EGFR,MBNL2,EFEMP1,CINP,ATP2C1,HBS1L,ERAP1,TXNL4A,GPR19,CACFD1,MAP4K5,IRAK3,RASSF8,ITPKB,MAP4,MAPT,ODF2,CCSER2,PRKAR1B,RAD51D,RGS12,MYH14,ZFP30,RBM34,ZHX3,CLSTN2,CEP68,SEMA4A,TMPO,PARD3,PLPPR2,VGF,PRDM2,KAT6A,SMIM8" Drug 2693_UP rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,FZD9,MTUS1,PKP4,SEMA4G,PLA2G4C,BMP7,CACNA1G,CFAP410,SCARB1,SYNGR3,HOMER3,CREM,ABCG1,SUSD5,FAM169A,FAM131B,DGKG,DAPK3,TRAPPC9,HIPK3,FER,FHL1,C1orf61,GABRA4,ERAP1,WASF3,GPM6B,GRIK2,WIF1,LYRM9,PCDH9,CNNM2,RAD51D,SUGCT,SCG5,FAIM2,DOP1A,TROVE2,ST5,ZNF34,PRMT8,TRPC1,TRPS1,ZFP37,ZBTB38,ZNF225" Drug 2960_UP Phensuximide [86-34-0]; Up 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "C1QTNF1,MRTFA,SLC4A4,ATP2A2,KIF1A,ADAM23,GYG2,CACNB2,THSD7A,CAPN3,REPS2,CHRNA4,CLTB,HOMER3,SH2B1,FAM169A,EFNA3,MRNIP,RASGRP2,ST3GAL6,FHL1,HPCAL4,AGAP2,MAN1B1,AFDN,CD200,GIT1,POLG,CEP41,RELN,CNNM2,TMEM231,SH3BP2,FNDC3A,ANKRD6,SLC11A1,BTBD7,RBM34,PEG10,DBNDD2,SPTAN1,LHPP,TBCEL,PSD3,GDPD5,NLRP3,SSPN" Drug 5524_UP Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "GAS7,CDC14B,PLA2G4C,PTCH2,CFAP410,USP2,CBFA2T2,CDH10,RAB33A,QKI,LRIG1,VCAN,GPRASP1,DAPK3,EDNRA,MTSS1L,NCALD,NRN1,TPK1,GUCY1A2,DHX35,ICA1,IGF1,MDM4,MSR1,CNOT4,STRN3,NECAB2,MAPK8,ELOVL2,CCDC40,ATG16L1,CNKSR2,PKNOX2,KIF13A,HECW1,IQSEC2,SYT11,VPS13A,SYN2,KAZN,SMG6,OBSL1,TK2,R3HDM1,KCNK12,HPS4" Drug 1484_UP Oxethazaine [126-27-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "PLA2G6,SRPX,CDC42BPA,MARK4,ASPH,CFLAR,ST3GAL5,ARHGEF7,SCAPER,BAIAP3,VCAN,NCAN,PPP6R2,RIMS3,EFNB3,MBNL2,ELN,LRRC23,F3,DLC1,SCARA3,OGA,DISC1,GPD2,GRIK5,ATXN2L,INPP5B,KCNH2,VWA5A,KITLG,MMP17,MYH6,SETD4,SERPINE2,RETREG1,PLTP,TRIM68,BCAN,ANKRD6,FAM214B,WDTC1,EMC1,VPS13A,KAZN,WSCD1,CHST5,TRO" Drug 2806_UP Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ACTN2,PLA2G6,CACNA1I,CACNA2D1,CBFA2T2,SEPT7,AKAP7,WHRN,SNCAIP,HS3ST2,DYNC1I1,DTNA,STX2,F3,FGF12,CAMSAP1,OGA,GFER,LILRA2,GRM7,KCNJ5,MATN3,AFDN,KCNK10,PDE1C,PLCD1,RAB3IL1,RAD52,C1orf54,RGS10,PNMA8A,TCP11L1,SYNDIG1,RASA3,CPEB3,RPH3A,EPN2,SMTN,PKNOX2,ARHGEF40,SLC20A2,CLSTN2,INKA2,SEMA4A,CABIN1,SYNC,KCNAB1" Drug 6799_UP Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "MRTFA,APP,PDXK,ASCL1,PDE8B,MARK4,ATP2A2,CACNA1A,ARHGEF1,CLGN,TAOK2,ZFYVE9,FADS2,SULT4A1,CDC42BPB,RASSF2,ANKMY1,ZNF589,PDLIM5,GPR153,GAB1,HLF,KHK,KIT,MEF2C,MPP2,MSI1,OGG1,EMID1,PEX26,FAM214B,ZSWIM8,CAMTA2,STX1A,SEMA4A,CRTC1,PCDHA6,TMEM121,TK2,TPM2,TRIO,FAM155A,KCNK12,SF1,ITM2C,EPM2A,KAT6A" Drug 4371_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ACTN2,AP2A2,MRTFA,AMPD3,AMT,APLP1,APP,DNAH17,BMP7,SYNJ1,GYG2,CA12,CRLF1,SOCS6,ASIC3,PLAA,CNTFR,CNTNAP2,EGR3,PLXNC1,TNK2,VPS13B,STX2,OLFM1,FGFR1,FGFR3,FOXG1,SEMA4D,PRELID3A,GPR37,TJAP1,KIFC3,KIT,MID1,NF1,MAPK10,PTPRE,RAD51D,FAM184A,ZCWPW1,RGS10,PLCB1,ROBO3,MCF2L,TK2,CDK20,FAM155A" Drug 5429_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "SYN3,ACTN2,SEMA4G,PPP4R4,LDLRAD4,CHRNA4,CSF1R,NCAN,RIMS3,SV2B,HS3ST2,SLC12A6,ATN1,EDNRA,SIDT2,EGFR,ING4,ELN,C3orf18,ERCC2,EFS,FOXG1,ALDH1L1,RUNDC3A,HPGDS,TJAP1,ITGA7,MAOB,MAP4,MSR1,LRRN3,PRKCB,MAPK7,RAB3A,SH3BP2,FAM214B,ARHGEF40,SHANK2,PDZD2,WDTC1,ZHX3,SPTAN1,CDK19,TNS1,TPM1,PLPPR2,PLSCR4" Drug 3578_DN "(+,-)-Synephrine [94-07-5]; Down 200; 24uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "SLC12A5,AK2,C1QTNF3,ARRB1,PDE8B,ASPH,CFLAR,CACNB2,CAMK2G,FADS2,AKAP7,ABI3BP,CRY2,CSNK1E,DBT,MFAP3L,ATN1,EPB41L1,MTSS1L,TPK1,USP19,ICA1,INPP1,MAPT,KITLG,MID1,NPR2,PMP22,PACSIN1,GON4L,WDR25,RAB3A,NLGN1,FAM214B,SLC6A8,CCDC88A,BTBD7,LIMCH1,KIF13A,ZHX3,ZNF423,POPDC3,KIAA0930,VAV2,NSD2,PRDM2,EVI5" Drug 5849_DN Glibenclamide [10238-21-8]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BRAP,PKP4,KCNAB2,DGKD,MARCH3,CDK5R1,CBFA2T2,FOXN3,CNOT8,VCAN,CTH,TM9SF4,FBXL5,EFNB3,ST3GAL6,FECH,B4GALNT1,GLRB,GPR37,SMAD1,MPP2,TAGLN3,LRP12,MINDY2,KLK6,BSDC1,RNH1,KIRREL1,TMEM156,ATXN1,SH3BGR,RAB3GAP1,RCOR3,PDZD2,SPATA7,CAND2,SRPK2,TAB2,ITPRID2,ST5,EXOC7,ARHGEF12,TJP1,RBFOX2,PLPPR2,ZFAND5,NAV3" Drug 1740_UP Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "CDC42BPA,APP,ARNTL,ASPH,ADAM15,MTMR3,CHRM4,ZFYVE9,TPP1,SEC31B,CLOCK,AATK,PPP1R16B,EDRF1,DCT,SRGAP3,TRAPPC9,SUGP2,NSG1,USP19,RAB30,GNG4,NXPH3,KLF12,ITGA7,ADAM22,PTOV1,NEUROD2,NF1,PALM,RASGRF1,TMEM206,ATXN2,SLC15A2,ELMO2,TNIK,IZUMO4,NXT2,ARHGEF9,VPS13A,TCF4,TCF7L2,TMOD1,SSBP2,WNK1,SLC17A7,NLRP3" Drug 2242_DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BIN1,CAPRIN2,ATP6V0A1,SYNJ2,HAP1,ARHGEF1,CBFA2T2,RAB28,AKAP7,SMARCAL1,SEC14L5,CTIF,MFAP3L,TMCC2,CDON,FER,FHL1,TMEM8B,POLL,GRB10,SPACA9,ADAM22,CNOT4,NUMA1,CDK18,PIK3CD,KCTD15,PRKAR1B,PTHLH,PTN,RAB3IL1,DCUN1D2,TCP11L1,EMID1,SEC14L1,PREX2,SNCA,LHPP,CLSTN2,THSD1,PLCB1,ARC,ROBO3,KAT6B,NDRG4,SYNC,EMSY" Drug 441_UP arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ALAD,CDC14B,ARRB2,SLC4A4,NRP2,CACNA1I,CAMK2G,INA,CBFA2T2,ARHGEF2,GREB1,B3GAT3,DNM2,DPP6,RCAN1,DTNA,STX2,TBC1D16,TUBB4A,TRMO,GPR153,ALDH1L1,RAB40B,NR3C1,ICA1,JAK2,MAP4,MYO6,NPY,NRGN,NTRK3,PLXNB1,FSD1,PTH1R,RNF220,RNASEL,SH3GL3,ELMO2,CDK5RAP2,SNAP25,RGL1,EXOC7,TBL1X,TRPM2,UCHL1,NDRG4,SPHK2" Drug 6252_DN Hexestrol [84-16-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NUMB,C5,PTBP2,ARMC8,C2CD2,AKAP12,ABCG1,ARHGEF10,DBT,HP1BP3,PARD6A,RABGAP1L,DPH1,ABCC5,RBM12,MRNIP,CDKL3,ANKMY1,F8,EFCAB2,GHR,ZNF276,GRB10,AGBL5,MAP4,LYRM9,NFYA,NUCB1,PDE3B,SMIM7,MSANTD2,SEC61A2,ROBO1,TCP11L1,TMCC1,KIF1B,ZBTB43,LHPP,ANKRD28,FAM208A,TCF7L2,KCTD2,HIRA,CADM1,LMF1,NUP214,ZNF248" Drug 3228_DN Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AP2A2,BIN1,APP,ALDH4A1,EPS15L1,WHRN,SMARCAL1,LRIG1,CDON,OPTN,EIF4G2,HSD17B14,MTSS1L,GABRA2,SRCAP,POLL,GNG4,CACFD1,GRM8,KCNQ3,LMO2,MPP2,SLC11A2,PC,CCSER2,RETREG1,PRKAR1B,RGS12,ROM1,EMID1,NLGN1,FAM214B,KDM4C,UNC5B,TROVE2,PLCB1,ATP11A,TNS2,PCDHA5,AHCYL2,THRA,ZKSCAN5,VGF,SYNC,KCNAB1,MARCH8,GAN" Drug 3986_DN Fusaric acid [536-69-6]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ALAD,TRMT9B,APC,APP,ASPH,MTMR9,BTRC,LHX2,CLU,RAB26,PICK1,NRG2,RABGAP1L,CHRDL1,MBNL2,SORBS3,LRRC23,DENND4A,VPS26C,EZH1,SRCAP,C1QL1,GNAS,LPAR4,GRM8,GUCY1A2,MN1,PAK3,PBX1,MYH14,KIRREL1,FRMPD1,ASAP3,NLGN1,SLC6A9,BTBD7,ARHGEF9,ARC,SYN2,RIMBP2,UBTF,OSBP2,XRCC4,TRIM9,REEP1,EVI5,MPPE1" Drug 6145_UP Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ANK1,APBB2,CDC14B,ATP1A2,ATP2B2,CBFA2T2,KCNAB3,ZFYVE9,ABCG2,CNIH3,KLHL3,SHANK1,EDNRA,EFNA3,MBNL2,EFS,ETV1,ADAM28,PCSK1N,STON1,ADAMTS13,KIF5C,AFDN,CD200,SAMD14,PDE4D,PPP2R2B,FAM120C,GAL3ST4,CARF,KCNIP1,RYR1,ASIC4,RPH3A,LIMS2,SLC9A5,SLC11A1,TMCC1,KDM4B,SOX10,AJAP1,WSCD1,TCF4,ATP13A2,TK2,UBE3A,DPF3" Drug 1940_DN Dehydrocholic acid [81-23-2]; Down 200; 9.6uM; PC3; HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AK2,PPFIA3,APP,BARD1,FADS2,CTNND1,C2CD2L,LYPD1,EXOG,SEZ6L2,APH1A,DMTN,TMEM164,AMOTL2,ATP2C1,TRAF3IP2,NCKAP1,CACFD1,NR3C1,MAN1B1,MBNL1,SETD4,TRHDE,STRN3,PPM1B,TMEM260,PTX3,RIPOR1,QDPR,BSDC1,ZFHX4,WLS,SFPQ,HSPA4L,WDTC1,NMNAT2,ZBTB43,DIP2A,ANKRD12,IQCE,OBSL1,FRYL,CBX5,TSN,ZFAND5,MPPE1,ACTR3B" Drug 3088_DN Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,PLA2G6,APOC1,LDLRAD4,CAMK2B,SCARB1,B4GALT6,NMT2,COL9A2,CLOCK,CREM,ARHGEF10,CTNND1,DBT,HIPK3,OPTN,EIF4G2,TNK2,COQ7,CD320,KAT8,CAMSAP1,EFCAB2,GABRA4,ALDH1L1,LILRB4,LILRA2,GRM1,IL6ST,PLCB2,PLTP,MAPK7,PTCH1,RAB3IL1,FBXW7,ZNF671,ARHGEF40,WDTC1,TNIK,PLCB1,KAZN,EXOC7,DNMBP,TPM3,TRPS1,FLRT2,TIGD6" Drug 2068_DN Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "APBA2,KCNAB2,ASPH,CFLAR,TAOK2,EPS15L1,ARHGEF6,CDC42BPB,DZIP3,SDC3,ARHGAP32,ZFYVE16,KIAA0586,FBXL5,SGSM2,TRAPPC9,DNM2,RBM12,SPEG,EFCAB2,POMT1,MATN3,ZNF862,NRGN,SETD4,PC,NLE1,MAPK7,SEC61A2,ASAP3,ST6GAL1,FAM214B,SMARCC2,CDK5RAP2,SPTAN1,ST5,NCDN,ELOVL4,FAM168A,ARHGEF9,IQCE,TBL1X,TRIM2,FAM155A,WNT7A,NDRG4,WIPF2" Drug 6843_DN Isocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADD3,ADRA1D,MRTFA,CDC42BPA,PPFIA3,ATP6V0A1,BCL2L2,BTRC,MAGI1,SOCS6,ZFYVE9,NMT2,CSF1R,ARHGEF4,FBXL5,MED24,GNE,DTNA,VPS26C,FGFR1,HSF2,MAPT,MMP16,NCAM2,CNOT4,MINDY2,PRODH,CNNM2,RAB3A,RGS12,ROM1,RPS6KA2,SBF1,ZNF365,PEX26,SMTN,SLC9A5,SLC22A4,SNCA,UNC5B,TTBK2,MCF2L,ZNF34,TK2,NPL,GDPD5,MPPE1" Drug 5044_UP Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASPHD1,ADCY2,ATP2B3,NRP2,BAIAP3,LDLRAD4,CACNG1,KALRN,CDH8,CRLF1,CACNA2D2,VAX2,WHRN,RGS6,CTIF,HS3ST2,TRAPPC9,HEYL,AGAP2,B3GAT1,SIGLEC8,GNG4,GRM7,FAM107A,IRAK3,IRF8,C2orf72,SMAD9,MAN2A2,MATK,MMP16,MYT1,NEUROD1,PCBP3,PIK3CD,NECAB2,SEPT4,SH3BP2,SLA,SLC8A1,SNCA,VAMP1,TNS1,TUBB1,VLDLR,VSNL1,PARP6" Drug 1502_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,BRAP,BEGAIN,CDC42BPA,AQP6,ALDH4A1,MTMR2,BTRC,CA12,DNAJB5,MFAP3L,DTNA,PHF20L1,F3,BAIAP2,EFCAB2,TRMO,DISC1,GNG3,GPM6B,TDRKH,GPR37,GRIK5,RNFT2,VWA5A,MBD1,TM6SF1,MDM4,NPTX1,NRGN,ODF2,NLE1,FAM184A,BSDC1,RPS6KA2,ZNF821,SH3BGR,SHANK2,RBM34,USP33,IQCE,SZT2,CRTC1,CABIN1,ZKSCAN5,VIPR2,MICAL1" Drug 4080_DN Cefadroxil [50370-12-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABR,NME5,APBB2,SEMA4G,MARK4,ASTN1,ATP2A2,ALDH7A1,ADAM23,C5,TAOK2,KIAA1549L,DNAJB5,RAB26,CNTFR,ENTPD4,CREB5,CSF1,VCAN,DZIP3,SNPH,MFAP3L,PLPPR4,SORBS3,MTSS1L,KCNMA1,ZNF862,NUMA1,PIK3R1,PMS2,PPP5C,GRAMD1C,TMEM231,KIRREL1,DOCK10,AMBRA1,DZIP1,SLC4A3,TMCC1,UNC5B,ASTN2,R3HDM1,TPM2,HIRA,MICAL1,ZBTB14,MAP3K12" Drug 7416_DN Cortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "KIDINS220,APC,DGKD,APP,NUMB,ATP6V0A1,REPS2,FOXN3,HOMER3,PDE4DIP,GREB1,RUBCN,EDRF1,DTNA,EML1,FGFR1,ANKFY1,CSPG5,ACOT7,HMGCL,DIPK1A,KCNJ3,KIF5C,MAPT,NEK1,NF1,CNOT4,PDE3B,KCTD15,PLEC,SLC25A23,VPS13C,TRAPPC13,ITSN1,FUZ,SYBU,SMARCC2,FNBP1,ZBTB43,TSPYL2,LHPP,EXOC7,TCF7L2,KAT6B,KLC2,EVI5,SEMA3B" Drug 5028_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,AP2A2,BIN1,APBA2,FAM131A,CADM3,CFLAR,CA4,CACNA1D,CLGN,CSF1R,SIPA1L1,CNTNAP2,PPP6R2,SEC14L5,TBC1D5,KIAA0586,MAML1,CDON,EN2,COQ7,LRRC23,ZNF589,IQCG,MALT1,KCNJ5,KCNN2,KIF5C,PBX1,NLE1,PLCD1,FAM120C,ARHGEF10L,SH3BP2,SMTN,KIF13A,ZHX3,LHPP,EXOC7,TCF7L2,RUNDC3B,TSC2,KLC2,GDPD5,MPPE1,MVB12B,KAT6A" Drug 7307_UP Triamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "KCNAB2,APP,PPP4R4,ALDH4A1,MAP7,CLCN3,STOML1,DNAJB5,HOMER3,WHRN,IFFO1,CRY2,PDE4DIP,HDAC9,ARHGAP24,SIDT2,REEP2,EFEMP1,TESK2,SORBS1,DENND2A,SYT17,STON1,ITIH2,MMP16,NFYA,PALM,PCDH9,SSH1,PLCD1,SMOX,LRRC49,PTPRN2,TMEM231,RALGDS,ZCWPW1,TTLL7,SCG5,PREX2,PEX26,DDN,MAPK8IP3,TIAM1,TPM2,ZMYND8,VLDLR,PHTF2" Drug 3264_DN Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AK2,AMT,ANK3,APC,GAS7,FAM131A,ASPH,ATM,CACNA1D,NMT2,CSF1R,RABGAP1L,EFNA3,EGFR,ING4,VPS26C,KIAA1109,FOXG1,PRELID3A,GNG4,GPD2,ELOVL5,TJAP1,KPNA5,MPP2,NPTX1,CDK18,PPP2R5C,PRKAR1B,RAD52,RGS12,SBF1,SUPT20H,PPP1R9A,BTBD7,IQSEC2,CLSTN2,SS18,PHLDB1,EXOC7,CRTC1,TRIO,TRPC1,WIPF1,SEMA3B,WIPF2,EPM2A" Drug 6096_UP (R) -Naproxen sodium salt [26159-34-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADRA1D,LTBP4,BEGAIN,KSR1,MYRF,KALRN,INA,EPS15L1,DNAJB5,NCOR2,ARHGEF10,SEC14L5,EDN1,LRRC23,SPEG,FGFR1,FYB1,ZNF44,GAD1,PRUNE2,ADAMTS13,SHISAL1,C2orf72,TJAP1,KIF5A,MAP4,AFDN,TAGLN3,P2RY1,KCNK10,EPN1,RGS12,KLHL11,RYR1,SLC30A10,SH3BP2,RPH3A,PEG10,SPTAN1,SPTB,CLSTN2,SYT11,SYT5,KIAA1107,SLC26A10,SLC30A3,SLC17A7" Drug 6301_DN Clopamide [636-54-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "MTUS1,EP400,ASPH,MTMR2,SOCS6,BAG4,USP6NL,KIAA0513,C2CD2L,SIDT2,LPAR6,EN2,ERCC2,SPEG,F3,B4GALNT1,ERAP1,GNG4,SLC2A6,KLF12,AGBL5,KCNMA1,ARHGAP12,MEIS1,TAGLN3,ZNF862,SLC11A2,PLCD1,MINDY2,PPP3CC,NDUFS7,PTK2,FAT4,GAL3ST4,SBF1,ASAP3,ZBTB43,SS18,ARHGEF9,PLCB1,IQCE,CBX5,PARD3,TNS1,XRCC4,WIPF2,MPPE1" Drug 3680_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASIC1,ARID1A,C1QTNF3,CDC42BPA,CDK10,NRG2,CREM,VCAN,HDAC9,SGSM2,DMPK,ATN1,EFNA3,MBNL2,ANKMY1,CINP,GBX2,GCNT2,GPR19,CACFD1,ELOVL5,KCNB1,KHK,TAGLN3,NF1,RETREG1,PLEC,SYTL2,PTHLH,TCP11L1,SAFB,SATB1,FUZ,SLC1A7,ELMO2,SNCA,EMC1,CDK19,ARC,FBXW11,TRIM2,DNAH7,PLPPR2,LAT2,NSD2,XRCC4,NAV3" Drug 2767_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADCY6,C1QTNF3,APC,PPFIA3,BMP7,GYG2,PLEKHB1,FAM189A2,DNAJB5,RAB26,HOMER3,CSNK1E,PDE4DIP,ARHGEF4,KIAA0513,TRAPPC9,CELSR3,TNK2,ANKMY1,SEMA4D,SRCAP,AHDC1,AGBL5,MAP4,ZNF862,NPR2,NUCB1,PC,PLEC,SIDT1,RAD52,RGS10,MCMBP,SBF1,SEC14L1,WDTC1,TSPYL2,FCHO1,STX1A,ATP11A,OBSL1,TMEM121,ZNF34,CABIN1,PLPPR2,VGF,HPS4" Drug 3475_DN Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,AP2A2,AK2,FAM131A,ST3GAL5,CRLF1,TAOK2,FAM189A2,CREM,CRY2,PDE4DIP,INTS1,MFAP3L,MED12,FEM1B,SIDT2,EIF4G2,ING4,ENO2,LRRC23,DISC1,RAB30,GNG4,LPAR4,JAK2,KHK,MAP4,GIT1,LYRM9,NRGN,PDPK1,RETREG2,POLG,PRPH,ZSCAN32,SEC61A2,NEK11,FERMT1,FUZ,ABLIM3,EPN2,SOX3,LHPP,NCDN,TMOD1,CDK20,TRPC1" Drug 4762_DN Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ARID1A,NDRG2,AP2A2,CDC14B,PDXK,CAMK2B,ARHGEF1,LHX2,FADS2,WHRN,NCOR2,ARHGEF10,CNTNAP2,GREB1,RIMS2,PPP6R2,DAPK3,ATN1,CNNM1,EFNB3,HSD17B14,FGFR3,C1orf61,GOLGB1,ZNF862,NPTX1,OGG1,PDE4A,SERPINI1,PRKAR1B,ELOVL2,CEP97,ZDHHC14,RET,RIC8B,ZNF821,SMARCD3,DOP1A,WDTC1,FNBP1,LHPP,MAPK8IP3,JMJD6,ARC,DMXL2,UBTF,MVB12B" Drug 5392_DN Metolazone [17560-51-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RALGAPA1,AP2A2,C1QTNF3,APLP1,CDC14B,ARHGDIG,BRINP2,ALDH7A1,SYNJ2,KYAT1,B4GALT6,SLIT2,AKAP7,SH2B1,EDRF1,JAKMIP2,CNNM1,ACSL4,FGFR1,CGREF1,OGA,SEPT9,RUNDC3A,GNG4,INPP5B,MDM4,MGAT3,MPP2,NEK1,NPR2,NLE1,PRKAR1B,PRODH,PEX5,ZDHHC14,RGS12,KDM4B,PHLDB1,MCF2L,CHST8,TGFBR3,BHLHB9,TPM1,CADM1,VAV2,CLDND1,ZNF45" Drug 5006_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "DPF1,KIDINS220,C1QTNF1,MRTFA,ANK3,CDC14B,ASPH,ATM,SCAPER,CFAP410,CACNG1,INA,ARHGEF1,CBFA2T2,HOMER3,ARHGEF6,RIMS3,DCT,DMPK,SIDT2,ERCC2,GABRA2,BTN2A1,LSS,KITLG,ADAM22,NOS1,PURG,PRKAR1B,MAPK8,MAPK10,BCAN,SLC1A7,LIMS2,KANSL3,COA1,TSNAXIP1,HECW1,INKA2,PLCB1,WSCD1,SLC35G2,KCNK12,MAP3K12,SLC17A7,EPM2A,PHTF2" Drug 2274_DN Methocarbamol [532-03-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RALGAPA1,ADRA1D,CDC42BPA,APLP1,FAM131A,ARRB1,ATM,SLC4A4,ALDH7A1,CFLAR,KRIT1,TAOK2,HOMER3,CNTN1,ABI3BP,RASSF2,MAML1,DBN1,DTNA,NCALD,ZNF589,FGF12,FOXG1,IQCG,PRELID3A,SRCAP,MSL3,STON1,SPACA9,INPP5B,ITPKB,JAK2,MSI1,ZNF862,PLCD1,PPP2R2B,MAPK8,GRAMD1C,ELOVL2,RGS3,TSNAXIP1,AHCYL2,ZMYND8,GDPD5,KAT6A,PHTF2,SSPN" Drug 1735_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "SEMA7A,PPP4R4,ALDH4A1,MTMR2,CAMK2B,CDC42,TAOK2,RAB33A,CLCN4,DNAJB5,AKAP7,DOCK4,BRINP1,DCT,DPH1,ZNF589,PDLIM5,GAP43,ERAP1,LUZP2,GRIK5,GRM1,NXPH3,HRH3,KCNN1,PAK3,PENK,LRP12,PRRX1,PACSIN1,DEF8,SAFB,ITSN1,AMBRA1,LIMS2,KDM4C,ZC3H13,IQSEC2,ARHGEF9,TACR1,OBSL1,TEX15,TMOD1,ZMYND8,TMPRSS5,FLRT1,SLC17A7" Drug 144_DN chlorpropamide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "SYT13,AMT,APBB2,GAS7,SLC4A4,ADAM23,ADAM15,BCL7A,CFLAR,CACNA1I,BAIAP3,CACNA1D,ARHGEF2,UBE2L6,FOXN3,EPS15L1,SEZ6L2,SRPK3,CEND1,TBC1D16,FLNC,GAP43,NEU3,SRCAP,ZNF276,CACFD1,SCIN,MPP2,ADAM22,OPCML,PALM,PRPH,BSDC1,GTDC1,ASIC4,FUZ,LIMS2,TMCC1,GANAB,IQCE,TCF7,SPX,PIK3R5,TRPM2,CA14,PRDM2,NUP214" Drug 4414_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ARID1A,APOC1,MARK4,SLC2A11,BCL2L2,CDK5R1,CHRNB2,LHX2,HOMER3,RCHY1,RIMS2,RIMS3,SPOCK2,SLC12A6,OPTN,HSD17B14,ERCC2,FHL1,SEMA4D,GAB1,GAD1,SRCAP,GLYR1,GRM8,ICA1,KCNJ3,LMO2,LYRM9,NDUFA5,CNOT4,PLCD1,PPP5C,MAPK7,PTHLH,C1orf54,GSTCD,ROM1,ASAP3,FAM214B,KDM4B,AJAP1,SEMA4A,EXOC7,SZT2,DICER1,TMOD1,FLRT2" Drug 2425_DN Naringin hydrate [11032-30-7]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABR,KIDINS220,GAS7,CASK,ARNTL,SCAPER,MTMR2,C5,SLC25A14,SPAG9,QKI,NIPBL,FEZ1,SOCS5,DBT,DTNA,ING4,ZNF589,CAP2,PCYOX1,TRMO,LILRA2,KIF2A,IPO5,MAP4,NUMA1,ZFYVE21,PLCB2,SLC25A23,RC3H2,MINDY2,MAPK3,PTAFR,ZSCAN32,SAFB,SEC14L1,ZCCHC24,NXT2,FAM168A,ANKRD12,TCF7L2,ZEB1,KAT6B,ZNF24,LAMP5,PHTF2,NLRP3" Drug 871_DN ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABHD6,ADCY6,MRTFA,CDK10,GYG2,C5,CLCN3,NIPBL,AKAP12,ARHGAP32,HDAC4,RIMS3,PARD6A,F8,SCML2,FHL1,NOP56,EFCAB2,TRMO,SESN1,GPD2,DHX35,LSS,NF1,NRCAM,PMS2,PTCH1,ACSS3,ITSN1,PPP4R3A,SLC15A2,ZCCHC24,ZHX3,SP2,SPTAN1,TACC1,SEMA4A,FAM208A,IQCE,KIAA0930,TCF7L2,AHCYL2,KAT6B,ZMYND8,VGF,PCBP4,SMIM8" Drug 3876_DN Oxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "CDC42BPA,GAS7,APLP1,SLC2A11,BCL7A,CFLAR,CA12,MAGI1,BAG4,NCOR2,DZIP3,CTIF,DSCAM,MAMLD1,ING4,HSD17B14,ERCC2,KAT8,ZNF589,CGREF1,HBS1L,SRCAP,AHDC1,FERMT2,GPER1,GRM8,IL6R,MAP2,KITLG,MMP17,TNPO2,RAD51D,RAD52,RGS10,SELL,LIMCH1,MAPKBP1,ZCCHC24,ZNF423,IQSEC2,CEP68,ARHGEF12,HEY1,LMF1,ZIC3,MAP3K12,EPM2A" Drug 4684_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADD2,APC,CFLAR,BTRC,CHM,RCHY1,NCOR2,ARHGEF4,DCT,C2CD2L,SPOCK3,TOM1,SRPK3,ETV1,EZH1,ZNF589,OLFM1,DPYSL4,PDLIM5,GAD2,LYVE1,GPR19,JAK2,SMAD1,ADAM11,MYO7A,NF1,NFYA,PFKFB2,MINDY2,CNNM2,MARCH1,RAD51D,SH3TC2,BSDC1,SELL,DOCK10,SLC6A9,SLC9A5,ATP10B,TBCEL,TRO,TRPC1,HIRA,VAV2,ZIC3,ZNF24" Drug 6801_DN Pyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AP2A2,NME5,PPFIA3,PLA2G4C,ALDH7A1,UBE2L6,BAG4,CREM,CSF1,SOCS5,CTH,MFAP3L,C2CD2L,EDNRA,HIPK3,NCALD,ANKMY1,FAM198B,FOXG1,SEMA4D,NOP56,PRELID3A,SEPT9,RAB30,CNTRL,MUM1,NEK1,NF1,NPR2,PDE3B,SMIM7,ZSCAN32,TMEM231,RGS10,CCDC25,SH3BP2,RAB3GAP1,SHANK2,LIMCH1,MAPKBP1,ELOVL4,PLCB1,ASTN2,TRPC1,VGF,EMSY,ST7" Drug 7018_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "APBB2,GAS7,CFLAR,SCAPER,LRRFIP1,VAX2,DNAJB5,QKI,AKAP12,FEZ1,PDE4DIP,KIAA0513,GIT2,TMCC2,DLG3,DTNA,EPB41L2,PRKAG2,TACC2,GAD2,GLS,PRRC2B,GPER1,GRK4,BTN2A1,IL6R,KCNF1,KCNJ5,MAP4,LYRM9,NEK1,NF1,OPRL1,PTAFR,RALGDS,CCDC25,PEX26,WDTC1,ZSWIM8,PHLDB1,SEMA4A,CAMSAP2,ATP13A2,CHST5,NDRG4,PRDM2,STMN4" Drug 2288_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,GAS7,PRX,ARHGDIG,MARK4,ATP1A2,SLC4A4,ATP2B2,FGF17,CAMK2B,RUNX1T1,USP2,ASIC3,CNN3,CNTFR,CSF1,CSF1R,DMPK,ATN1,EFNB3,EIF4G2,SCARA3,PDLIM5,GPR162,RAPGEF1,GRM1,MAOB,MAP4,MEF2C,MGAT3,MOBP,MSR1,NTRK2,OMG,PALM,PDE4B,PFKFB2,SAMD9,PTPRH,C1orf54,DDN,ATP10B,PHLDB1,EXOC7,CRTC1,TRPM2,DNALI1" Drug 5545_DN Isoflupredone acetate [338-98-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "PPP4R4,MARK4,ATM,ADAM23,ADAM15,CFLAR,MTMR2,BAIAP3,CCKBR,ARHGAP33,LRRFIP1,TAOK2,FAM189A2,QKI,GIT2,DUSP9,DMTN,ANKMY1,PRELID3A,CNTRL,SPACA9,HNMT,KCNJ3,KCNQ3,LMO2,VWA5A,MAP4,RETREG1,MAPK8,RAD52,BSDC1,RGS12,GSTCD,NEK11,SLC1A7,PPP4R3A,RIMS1,SNCA,ZCCHC24,ZHX3,EXOC7,TNS2,PIK3R5,HIRA,VAV1,EMSY,KAT6A" Drug 3831_UP Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "APOC1,PPP4R4,CACNA1I,LDLRAD4,USP2,NEURL1,FADS2,SULT4A1,CRYM,DAPK3,CTIF,ATN1,DTNB,EIF4G2,EPB41,RASGRP2,CEND1,FGF1,OLFM1,CAMSAP1,C1orf61,SRCAP,C1QL1,GPER1,DHX35,KCNQ3,KIFC3,LSS,KITLG,MMP17,PCBP3,CDK18,PFKFB4,PIK3CD,TNPO2,SLC6A11,SLC11A1,ZEB1,PCDHGA10,SYNE1,TNFRSF1B,PIK3R5,TRIO,ZBTB38,SCG2,MVB12B,NUP214" Drug 7515_UP CP-645525-01 [287190-82-3]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ACLY,ABHD6,NME5,DNAH17,KIF1A,CFLAR,FUBP1,CBFA2T2,EPS15L1,DAPK3,SPOCK3,CDON,ABI1,TOM1,OPTN,EFNB3,PLXNC1,REEP2,FGFR1,MSL3,LPAR4,SYNPO,MYO7A,ZNF862,OCRL,OMG,PPP5C,MAPK7,LRRC49,PTCH1,ZSCAN2,RAB3IL1,RPS6KA2,CLIP1,LIMS2,FAM214B,NMNAT2,AJAP1,TBL1X,TCF7L2,TRIM2,BEX4,PARD3,PRMT8,ZNF184,WNK1,RNF146" Drug 7012_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASPH,GYG2,CHRNB2,TPP1,TCEAL2,ARHGEF10,SOCS5,MFAP3L,RCAN1,DTNA,ENO2,MTSS1L,EPHB1,FHL1,GABRA2,GAD1,LYVE1,GLYR1,RAB30,GPR75,LPAR4,CNTRL,GRM8,HNMT,MAP4,MDM4,GPR85,SAMD9,PTHLH,RAB3IL1,C1orf54,ZNF821,BCAN,ABLIM3,KANSL3,COA1,SNCA,ERC1,IQCE,NR2C2,AMACR,TRPC1,TRPC3,KCNK12,ZBTB14,NDRG4,PRDM2" Drug 4185_DN Probenecid [57-66-9]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ADRA1D,PLA2G6,APLP1,ARRB2,ADAM23,CDK5R1,LHX2,NRXN3,DNAJB5,WHRN,RGS6,ARHGEF10,CNTNAP2,SGSM2,ATN1,MBNL2,SORBS3,LRRC23,MTSS1L,ST3GAL6,FGF1,FOXG1,GAB1,GPM6B,LPAR4,GRIK2,GRM1,SOX21,RASSF8,SCIN,ODF2,ENPP2,PIK3R1,RETREG1,PTPRB,ZCWPW1,FRMPD1,KANSL3,WDTC1,SOX2,VAMP1,THRA,TIAM1,OSBP2,VGF,VIPR2,KCNAB1" Drug 4453_DN clozapine; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RALGAPA1,KIDINS220,CDC42BPA,APC,CDK10,ATP2A2,ADGRB2,ST3GAL5,IL33,BTRC,MAP7,CLCN4,HOMER3,CREM,HIPK3,SIDT2,EGFR,EPB41L2,LRRC23,KIAA1109,TRMO,HBS1L,MEF2C,MIA2,NUMA1,CLDN11,PAK3,PFKFB2,NLE1,PPP5C,MAPK7,GRAMD1C,CNNM2,CNTLN,PTPRN2,RAB3IL1,RALGDS,ATG16L1,FBXO11,PPP4R3A,SNCA,BEX1,SS18,COBL,EXOC7,KIAA1107,PHTF2" Drug 762_UP alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASIC1,ADD2,AK2,AMT,APBA2,APBB2,ARNTL,ATM,CADM3,CFLAR,CA12,NFS1,KRIT1,SOCS6,TAOK2,NIPBL,CDC42BPB,ZNF337,B3GAT3,SRGAP3,AK5,ANKRD46,MBNL2,FCGRT,DENND2A,PRRC2B,CNTRL,KIF3A,RNFT2,SMAD1,MKLN1,TNPO2,MAPK3,TMEM104,SEC61A2,CCDC25,ZC3H14,MAPK12,DOCK10,SIRT2,KBTBD4,ELMO2,ZHX3,ST5,TMPRSS5,DNAJC12,ZNF184" Drug 3846_DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,MRTFA,CDK13,C5,BAIAP3,TAOK2,CLU,CSF1,CNTNAP2,DCAF4,GIT2,ZNF804A,SLC12A6,TOM1,SORBS3,PLEKHO1,ZNF589,PRELID3A,CACFD1,KCNJ3,MAP4,MMP16,ADAM22,NPR2,PLEC,PLXNB1,MAPK7,SNRK,ZSCAN2,RAB3A,ZDHHC14,ZMAT4,TRIM68,TCP11L1,EMID1,SBF1,SH3BP2,LIMCH1,WDTC1,IQSEC2,SYN2,EXOC7,KIAA1107,TCF7,TNS1,LAT2,EMSY" Drug 1950_UP Josamycin [16846-24-5]; Up 200; 4.8uM; PC3; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "BIN1,ALDH4A1,FUBP1,GYG2,CAMK2B,CLDN10,CCNT1,INA,CHRM4,CRY2,CTH,RASSF2,AK5,E2F5,SPEG,ACSL4,FGFR1,PDLIM5,TRAF3IP2,DENND2A,B4GALNT1,TDRKH,INPP5B,NELL2,NTRK3,PBX1,PDE3B,PLCD1,C19orf57,GON4L,RGS4,RPRD1A,SH3BP2,SLN,SMARCD3,TSPYL2,NXT2,MAPK8IP3,WSCD1,NSD1,UCHL1,SF1,MAP3K12,EVI5,PARP6,SLC17A7,DPF3" Drug 3292_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ASIC1,SEMA6A,MARK4,BCL7A,BMP7,C5,BTRC,HAP1,CCNT1,SCARB1,LRIG1,FAM169A,RUSC2,RABGAP1L,MBNL2,SCML2,C1orf61,SEMA4D,EFCAB2,GPR153,GAB1,B4GALNT1,ERAP1,DISC1,SRCAP,CRCP,HTATSF1,MAP4,NF1,NUMA1,PDE3B,PDPK1,STRN3,MED1,WDR25,PTHLH,FAM184A,RNASEL,ROM1,WLS,FUZ,SLN,ARHGEF9,TCF7L2,AHCYL2,VGF,SF1" Drug 4779_UP Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "PPP4R4,BRINP2,ATM,MTMR2,BTRC,CAMK2G,RCBTB2,STOML1,COL9A3,SOCS5,DCAF4,SPOCK3,EFNA3,EGR3,ING4,GPHN,STX2,DENND4A,ARMCX1,ZNF589,IQCG,GABRA2,ERAP1,VSIG4,KCNN2,LIG4,MBNL1,ADAM22,NF1,NPY,SLC25A23,PTAFR,CPEB3,PPP4R3A,SLN,PEG10,NXT2,POPDC3,WSCD1,TRIM2,ARHGEF12,BEX4,CHST5,DNAJC12,VLDLR,WIPF1,CLDND1" Drug 5469_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ACTN2,SLC12A5,ALAD,CDK10,NCOA1,LRIG1,PDE4DIP,DCAF8,DAPK3,DLG3,DSCAM,SIDT2,RGS17,EPB41L1,ANKMY1,DLC1,TESK2,DPYSL4,USP21,INPP5K,GART,MSL3,GOLGB1,MUM1,MAN1B1,MAPT,MPP2,NCAM2,NF1,PC,SLC25A23,NKAIN1,GTDC1,SFPQ,AMBRA1,SMTN,FAM214B,NCDN,PHLDB1,FAM168A,ARHGEF9,MTCL1,TAF6,KCTD2,CABIN1,TRIO,HPS4" Drug 7488_DN ST021200; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RALGAPA1,C1QTNF3,GAS7,SLC4A4,BTRC,CAMK2G,CBFA2T2,CDC27,SLIT2,NMT2,HDAC4,CTIF,GIT2,JAKMIP2,DTNA,ING4,STX2,PIPOX,KIAA1109,TRAF3IP2,HBS1L,ATP8A2,SYNPO,KIT,AFF1,ZNF862,PRKAR1B,MAPK7,PRPH,RAB3A,RAD51D,MYH14,ZNF821,SLC15A2,SMARCD3,RCOR3,KDM4B,KDM4C,MAPK8IP3,VPS13A,PLCB1,WSCD1,RPGRIP1L,SLC44A1,HEY2,UCHL1,REEP1" Drug 5678_DN Thonzonium bromide [553-08-2]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "RIPK1,CA4,TBRG4,HOMER3,SLC4A7,ARHGEF10,SIPA1L1,DZIP3,MFAP3L,SORBS3,EIF5,ZNF589,PDLIM5,PRELID3A,CGREF1,TBR1,TRAF3IP2,INPP5K,MALT1,GLYR1,RASSF8,HNMT,MAPT,MMP16,ADAM22,NF1,NFYA,SLC11A2,NUMA1,PDE4A,TMEM104,PTHLH,PTPRE,FAM184A,FOXRED2,SLC1A7,SLC22A4,WDTC1,EMC1,ELOVL4,AP4E1,CABIN1,ZNF24,ZNF74,SMIM8,PHTF2,ACTR3B" Drug 5490_DN Niflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "AK2,C1QTNF3,SRPX,APOC1,APP,KIF1A,C5,RAB28,NMT2,VAX2,QKI,AKAP7,SLC4A8,BAG4,CTNND2,ZNF337,C2CD2L,SGSM2,DLG3,DSCAM,MAMLD1,CNNM1,SIDT2,ENO2,PCLO,TM6SF1,NF1,ODF2,PPP5C,RGS10,RGS12,SEC61A2,GSTCD,SBF1,PEX26,LIMCH1,MAPKBP1,CDK19,SPART,VPS13A,TIAM1,NPL,UBTF,PLPPR2,ZNF74,EPM2A,RNF146" Drug 2281_DN Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "KCNAB2,APC,DNAH17,ALDH7A1,CFLAR,CA4,MAGI1,LYPD1,RCAN1,EGFR,PLXNC1,DMTN,CAMSAP1,FOXG1,C1orf61,EFCAB2,TPK1,SRCAP,GLYR1,RAB30,STON1,NR3C1,INPP5B,MPP2,NF1,PLCD1,PTN,KLHDC8A,CCDC25,TCP11L1,SUPT20H,SH3BP2,ZCCHC24,IQSEC2,CLSTN2,TTBK2,PLCB1,TCF7L2,NSD1,CRTC1,BHLHB9,VGF,KCNK12,SLC30A3,KCNAB1,WIPF2,TIGD6" Drug 3511_DN Roxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ABR,NDRG3,ADD1,AK2,MARK4,KYAT1,VAX2,SH2B1,NCOR1,LRIG1,CSNK1E,PDE4DIP,RIMS3,MAML1,TOM1,SUGP2,EZH1,KAT8,FHL1,ANKFY1,HBS1L,TXNL4A,NR3C1,MAN1B1,INPP1,MAPT,MATK,MBD1,KITLG,NUCB1,FSD1,TMEM104,PTCH1,PTPRG,ZCWPW1,SUPT20H,SH3BP2,RBM34,STX1A,EXOC7,SATB2,TCF7L2,CHST8,ZKSCAN5,ZBTB14,WNK1,SSPN" Drug 5491_UP Pizotifen malate [5189-11-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,ADGRF5,AMPD3,BIN1,APP,CDC14B,SCAPER,USP2,ARHGEF1,NRG2,AATK,MICAL2,IPCEF1,DCT,HP1BP3,MBNL2,ELN,EN2,SPEG,SRCAP,NR3C1,DHX35,TJAP1,KCNH2,KCNJ3,GIT1,NUMA1,OPRL1,MTRF1L,LRP12,RGS4,KLHDC8A,RPS6KA2,ZNF821,MRAS,SH3BP2,SLC6A8,ZNF334,SLN,TMCC1,TROVE2,PLCB1,TEX15,RIMBP2,TRPM2,LMF1,KCNK12" Drug 5314_DN Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "ARID1A,ADD3,PPFIA1,APC,APP,NCOA1,MPDZ,BCL2L2,CCNT1,REPS2,COL9A2,ZNF337,KIAA0586,HP1BP3,GNE,SEZ6L2,CDKL3,TRMO,MAP4K5,MUM1,ACOT7,KHK,KIF5C,NPR2,SETD4,ODF2,RETREG1,GON4L,ARID4A,MAPK12,AMBRA1,EPN2,ELMO2,FNBP1,KDM3A,CDK19,TAB2,CLASP2,SYT1,EXOC7,CAMSAP2,TBL1X,RBFOX2,ZNF384,TRIO,CADM1,FTSJ1" Drug 1380_UP Spironolactone [52-01-7]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG2,APAF1,CDK10,PDXK,ARNTL,ATM,RIPK1,SLC25A14,CBFA2T2,SRSF11,HINFP,CTH,ZNF804A,VPS26C,CD320,FCGRT,ATP2C1,GLYR1,GLS,PCSK1N,GRIK5,MAN1B1,IDH3A,ODF2,SLC25A23,MINDY2,PTX3,ZDHHC4,SGK1,ITSN1,KBTBD4,ELMO2,GLT8D1,UHRF1BP1L,KDM4C,TSPYL2,SEPT8,VAMP1,TAC3,TBL1X,CHST8,CBX5,CA14,ZKSCAN5,PRDM2,EVI5,URM1" Drug 1766_DN Cytisine (-) [485-35-8]; Down 200; 21uM; HL60; HG-U133A Broad Institute CMAP Down 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "NDRG3,NDRG2,AK2,APBA2,ATM,CFLAR,BMP7,SYNJ2,CAST,CD86,SLC4A7,CSF1,TM9SF4,SPOCK2,GIT2,F3,PDLIM5,DISC1,LILRB4,MAN1B1,ELOVL5,MAP4,OCRL,PFKFB3,CDK14,PLCD1,RC3H2,PMS2,PRKAB2,GON4L,QRICH1,RAB3IL1,BSDC1,SH3BP2,DZIP1,PEX26,EMC1,POGZ,ITPRID2,TCF7L2,MTMR14,CABIN1,CHST5,ZMYND8,UBE3A,ZNF24,UBE3B" Drug 5469_UP "(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.06E-03 1.00E+00 1.28E-02 1.46E-01 47 198 "SPARCL1,SYT13,AMPD3,GAS7,CDC14B,ARHGDIG,MARK4,CADM3,BAIAP3,EPS15L1,COL9A3,RGS6,CTH,SPOCK2,DRD1,ELN,TUBB4A,CORO2B,ZNF589,BAIAP2,FOXG1,FLT1,ANKFY1,FYN,GLS,GPR37,GUCY1A2,KCNJ5,KCNMA1,LSS,MAN2A2,MOBP,CD200,NF1,PDE4D,LRP12,RAD52,RPS6KA2,KIF21B,PEG10,TCF4,RPGRIP1L,PSD3,OBSL1,TRPC1,VAV2,LMF1" Drug ctd:D008767 Methylmercury Compounds CTD 2.06E-03 1.00E+00 1.28E-02 1.46E-01 167 863 "SERPINA3,ABCF1,ACADM,ACHE,CLK4,AS3MT,NDRG2,AP1B1,AGT,OSBPL1A,AK2,EP400,APAF1,APC,VAT1L,APOC2,APP,DDX3Y,ATP2B2,ALDH7A1,ADGRB1,NRP2,CACNA1G,CALM1,PTBP2,CH25H,CBS,INA,CDC42,COPB2,CHGB,CHN2,CHRM1,ZBED5,SLC22A6,TPP1,FADS2,CP,RBM39,NCOR2,CSF3R,CSNK1E,CST3,CTNND1,DLG4,DLX1,MED12,FARSB,DNM1L,TSPAN5,EEF1A2,HIPK3,EGFR,EIF4G1,ELAVL4,COQ7,GPHN,SLC43A2,SRRM1,PIPOX,FABP7,TUBB3,TUBB4A,RACK1,FECH,FGF13,AMOTL2,FOXG1,FLT1,NOP56,PDLIM5,ERGIC3,FYN,SALL3,GFAP,ZNF638,GOLGB1,GPD2,GRIK2,ADAMTS13,GSN,FAM107A,MAN1B1,NCKAP1L,ELOVL5,HMGCR,HNRNPK,AGFG1,HSP90AA1,IGFBP1,JAK2,KIF5C,KTN1,LAMP2,LSS,MAOB,MAP2,MAPT,MBP,MEST,MYH7,NCAM1,NEFH,NEUROD1,NFE2L2,NOS1,OGG1,PAH,PDGFRA,ABCB1,PIK3C2A,PIK3R1,CCSER2,TMEM38A,PLP1,MAPK3,MAPK8,MAPK9,GDPD1,PEX2,RAP1GAP,ARID4A,RGR,RNH1,ELP2,MRAP2,RPL38,RTN1,S100B,SBF1,ATXN2,FERMT1,SLC1A2,SLC1A3,SLIT1,EPC1,SMARCC2,SMARCE1,SNAP25,SNCA,SOX5,NFASC,APOM,ACSBG1,SYT11,SUPT5H,VAMP1,SYP,SYT1,CAMSAP2,TCF7L2,DNAH7,AKTIP,CABIN1,TPM1,NPL,TPM2,TPM3,NR2C2,UBC,UCHL1,TUBA1A,SCG2,HNRNPA3,IFT88,RNF146,CPNE4" Drug 3028_DN Moxalactam disodium salt [64953-12-4]; Down 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "PKP4,APAF1,NCOA1,CAMK2G,CBFA2T2,QKI,HOMER3,SLITRK5,RUBCN,TBC1D5,DBT,DCTN1,NR1D2,DTNA,FIS1,HIPK3,FCF1,GPHN,PDLIM5,MPP6,GPD2,GRB10,NCKAP1L,ITGAM,LIG4,SMAD1,MDM4,NF1,NFYA,PIK3CD,SLC25A23,RC3H2,TMEM231,TRIM68,GTDC1,C12orf49,NSFL1C,EXOC7,TCF4,AHCYL2,KCTD2,KAT6B,CABIN1,LAT2,NSD2,EMSY" Drug 3799_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ABHD6,ADCY6,BIN1,PPP4R4,RASL11B,SYNJ2,C5,TAOK2,CLCN4,DNAJB5,HOMER3,NRG2,TENM4,TOX,DAPK3,DTNA,MBNL2,ING4,ZNF589,TDRKH,EML4,GPR37,ATXN2L,SHISAL1,SCIN,IL6ST,IL11RA,IL12A,KIF5C,LIFR,MAPT,SCAMP5,NF1,PIK3R1,PTHLH,ARID4A,RGS10,ZNF671,CSRNP3,TSNAXIP1,TCF7L2,TIAM1,VGF,LAT2,XRCC4,PLSCR4" Drug 3672_DN Clemizole hydrochloride [1163-36-6]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ARID1A,APC,CDK13,MARCH3,ALDH7A1,NRP2,CA12,HAP1,SCARB1,SEPT7,CNTFR,AKAP7,IQCK,ARMC8,HAPLN1,VCAN,GPRASP1,DBT,DMPK,DUSP9,GPR19,CACFD1,IL11RA,MAPT,MIA2,PAK3,PIK3R1,PRKAR1B,ROM1,DZIP1,SLC1A7,COA1,SNCA,WDTC1,TNIK,KDM4C,TROVE2,SS18,TRIM2,GPR161,BHLHB9,TNS1,LMF1,WNT7A,TRIM9,KAT6A" Drug 431_DN troglitazone; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ARID1A,NDRG2,LGR5,ASCL1,STX16,BMPR1B,CACNA1I,CBFA2T2,CHRNB2,TAOK2,IFFO1,ZNF804A,ATN1,RCAN1,SUGP2,EGFR,SORBS3,LRRC23,EPHB1,ETV1,FYN,AHCYL1,NEU3,TXNL4A,AP4S1,MAPT,MEF2C,MYL3,EPN1,PTX3,RGS12,RNASEL,SATB1,ATXN2,SIRT2,MAPKBP1,CLASP2,GANAB,WSCD1,KIAA0930,CABIN1,TNS1,FAM155A,KCNK12,SH3GLB2,GDPD5" Drug 5909_DN AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "KIDINS220,ANK1,APP,ADAM15,KSR1,CDK5R1,BTRC,B4GALT6,QKI,HAPLN1,PDE4DIP,TMCC2,CHRDL1,DNM2,RCAN1,NCALD,EXTL2,SCML2,OLFM1,GAB1,GLRB,EML4,ITIH2,KCNJ3,VWA5A,ADAM22,CDK18,GPR85,PENK,PRKAR1B,ZNF821,MRAS,ANKRD6,TMCC1,SPTB,NXT2,COBL,ICAM5,METTL3,OSBP2,WIPF1,CLDND1,WNK1,SCG2,NAV3,NUP214" Drug 2561_DN Dicumarol [66-76-2]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "C1QTNF3,CDK13,ZBTB10,SLC4A4,SCAPER,CD86,QKI,ENTPD4,TM9SF4,DBT,DTNA,FCF1,FCGRT,ANKFY1,MSL3,LILRA2,ICA1,ITGAM,MIA2,SLC11A2,RC3H2,POLR2F,GTDC1,MRPS18A,C12orf49,GSTCD,ZNF331,ATXN1,SEC14L1,GALNT10,ZFP30,NUBPL,ZKSCAN3,KIF1B,CDK19,NCDN,MAPK8IP3,ATP11A,EXOC7,FBXW11,DMXL2,KCTD2,SSBP2,FLRT2,WIPF1,NSD2" Drug 3181_DN Ethacrynic acid [58-54-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ADCY6,DOC2A,PPFIA3,CAMK2G,TAOK2,SDC3,RABGAP1L,EFNA3,RBM12,FGFR1,FGFR3,BAIAP2,CGREF1,TXNL4A,POLL,CNTRL,GRB10,PADI2,ITPKB,KCNF1,MAP4,LRP12,MBOAT7,WDR25,CEP97,RGS3,ARHGEF10L,EMID1,AMBRA1,KIF13A,WDTC1,SOX3,MAPK8IP3,STX1A,TACC1,IQCE,AHCYL2,ZNF34,SLC44A1,TIAM1,NPL,ZMYND8,HIRA,VAV1,EMSY,C12orf4" Drug 6435_DN AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ADD1,NME5,AK2,CDC42BPA,PKP4,CNTNAP1,EPB41L5,ARNTL,PLA2G4C,ALDH4A1,CDK5R1,SYNJ2,CA4,CACNG1,ENTPD4,MFAP3L,SMG7,NR1D2,F3,WAC,TRAF3IP2,ZMYND11,ARFIP1,HTATSF1,GRIK5,RASSF8,INPP5B,MAP4,NFYA,NNAT,NOS1,NUMA1,MAPK7,ZSCAN32,FOXRED2,FBXO11,PALLD,LHPP,SMG6,EHBP1,SLC44A1,VGF,LAT2,WNK1,PRDM2,UBE3B" Drug 4341_UP Vincamine [1617-90-9]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ACHE,ACTN2,SLC12A5,PPP4R4,BRINP2,BAIAP3,CHRNB2,ARHGAP22,TPP1,DSCAM,EDN1,TENM1,TNK2,PDLIM5,TRAF3IP2,HBS1L,RND1,IL6ST,DIPK1A,TM6SF1,MOBP,DDR2,OPRL1,LRRN3,PRKAR1B,MAPK8,PTX3,KIRREL1,ATXN7,SH3BP2,SLA,SLC1A7,SP4,HECW1,ZNF423,RBM26,KAZN,MCF2L,DMXL2,TUB,UCHL1,VSNL1,SF1,NAV3,SLC17A7,KCNAB1" Drug 3103_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "OSBPL1A,AMPD3,APC,N4BP2L1,CAMK2B,HIP1R,SCARB1,NMT2,COL9A2,ZNF337,TM9SF4,SMG7,RCAN1,DTNA,HIPK3,FRY,GPHN,CAMSAP1,FLT1,ALDH1L1,GLS,ITGA7,ITGAM,LAMA2,SMAD1,ZNF862,NF1,CDK14,TRHDE,MAPK8,ZSCAN32,FAM184A,BEND5,LGR4,SCG5,MAPKBP1,DOP1A,TNIK,TCF7L2,THBS4,KCTD2,PARD3,TPM3,LAMP5,ACTR3B,LAS1L" Drug 7147_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "CDK10,MADD,NRXN3,ZFYVE9,CNTNAP2,RUSC2,TRAPPC9,OPTN,EFNA3,LPAR6,EIF5,TUBB4A,SEMA4D,CGREF1,FYN,GAD1,ERAP1,GFER,TDRKH,INPP5B,KCND3,KIF5C,MAP4,MAPT,ADAM22,MYO9A,SETD4,PTPA,ZSCAN32,PTPRH,MAPK12,PPP4R3A,LIMS2,SLC6A8,SHANK2,SLC14A1,WDTC1,TNIK,ZBTB43,VPS13A,TRIM2,DOCK9,CABIN1,RUNDC3B,TRPS1,EVI5" Drug 5922_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "TRMT9B,APP,PTCH2,BRINP2,ASTN1,ALDH7A1,ADAM23,CACNG1,ARHGEF2,CRLF1,FOXN3,PDE4DIP,CTNND2,ST8SIA3,ING4,FGFR1,FGFR3,GALC,GLYR1,GPR19,KLF12,ITGA7,KIF5C,MSR1,NF1,ODF2,PALM,PDE4B,MAPK8,RASGRF1,RGS7,SEC61A2,RAVER2,STK32B,S100B,IL17RB,SELL,PEX26,ZNF667,FAIM2,IQSEC2,MAPK8IP3,HIF3A,TNS1,RPRM,KCNAB1" Drug 1957_DN Methotrexate [59-05-2]; Down 200; 8.8uM; PC3; HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ACADM,AMPD3,APBB2,APP,ASPH,ATP2B1,CDC27,CDH2,HOMER3,NECTIN3,CTH,FBXL5,KIAA0753,SEC23B,ATP2C1,STAG2,NCKAP1,GLS,CLASRP,IL6ST,ITGAV,KIF2A,KTN1,LAMP2,NAP1L1,PCMT1,PDE1C,TRHDE,PPM1B,TTC13,RBBP6,CLIP1,SFPQ,GLT8D1,PEG10,RAP1GAP2,LARP4,ERBIN,DIP2A,STXBP1,KLHL7,ACTR6,UBE3A,EVI5,ST7,CERS6" Drug 7004_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ADRA1D,PLA2G6,LTBP4,ALDH7A1,SCAPER,RUNX1T1,NEURL1,ENTPD4,DOCK4,TMCC2,DNM1,ENO2,MTSS1L,VPS26C,FER,FHL1,SEMA4D,RUNDC3A,ADAMTS8,ELOVL5,HNMT,TJAP1,KCNF1,KIF5C,GIT1,NAP1L2,NF1,NPY,GPR85,PRKAR1B,PKN2,RALGDS,GTDC1,ROBO1,ZNF821,FBXO11,FAM214B,SLC6A9,SHANK2,SNCA,PHLDB1,AP4E1,EMSY,GDPD5,SEMA3B,NUP214" Drug 3908_DN CP-320650-01 [172079-28-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "CDC42BPA,PPFIA1,APP,PDXK,CAMK2G,SRSF11,B4GALT6,CNOT8,TMEM184B,CHD1L,AKAP12,LRIG1,DCAF8,MAML1,DBT,SMG7,DMPK,ABI2,STX2,CINP,GLYR1,GSN,INPP5B,ITGAV,KCNJ3,MPP2,NEK1,NPTX1,PC,SERPINE2,PPP3CA,RBBP6,SFPQ,ANKRD6,WDR37,SMTN,SLC20A2,PDZRN3,CDK19,RAP1GAP2,ITPRID2,GANAB,IQCE,TRIO,NDRG4,EVI5" Drug 3250_UP Carbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ADD2,PRX,BAIAP3,CDH10,CHRNB2,AKAP7,CREB5,TENM4,EDRF1,HP1BP3,TMCC2,ATN1,MBNL2,VPS13B,DLC1,FOXG1,GABRA2,GLYR1,ATXN2L,KCNMA1,KCNN2,MID1,MITF,AFDN,NNAT,LRP12,MINDY2,MAPK7,RAD52,SELL,PPP4R3A,BTBD7,SNCA,TSNAXIP1,CDK19,ATP11A,EXOC7,ZEB1,SZT2,TGFBR3,TMOD1,TMPO,SPHK2,SYNC,UPF3A,KAT6A" Drug 7427_DN Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "APC,PPFIA3,CDC14B,BMP7,CBFA2T2,UBE2L6,ABCG1,DCAF8,SGSM2,DLG3,SUGP2,APH1A,TNK2,EPB41L2,VPS26C,ANKFY1,ATP2C1,GHR,GPR19,MUM1,ARHGAP19,IPO5,MAP4,NF1,NFYA,SLC25A23,PMP22,POLG,CLIP1,ITSN1,ZNF365,RAB3GAP1,SMARCA4,SMARCC2,ZHX3,SPART,MAPK8IP3,CEP68,PHLDB1,SIN3B,TCF7L2,ARHGEF12,TP53BP1,TRPC1,HIRA,ST7" Drug 1982_DN Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; HL60; HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "EP400,APP,NCOA1,SYNJ1,KRIT1,LRBA,CDC27,CLCN3,QKI,NIPBL,ENTPD4,CTH,HDAC4,DMTF1,EPB41L2,KIAA1109,SEC23B,ATP2C1,GPR153,STAG2,HTATSF1,HNMT,KTN1,MYO9A,NFE2L2,PIK3R1,DPF2,RPRD1A,AP1AR,SBF1,ATXN2,DOCK10,FBXO11,BCAN,CCDC88A,SP2,RBM26,SPART,TAB2,CLASP2,SAMSN1,SUPT5H,AGTPBP1,TCF7L2,WIPF1,CERS6" Drug 4205_DN Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "MTUS1,TRMT9B,ARRB2,ARHGAP22,LHX2,NRXN3,PLAA,DNAJB5,RGS6,TOX,BRINP1,C2CD2L,SGSM2,DLG3,ATN1,SORBS3,LRRC23,ERCC2,FYB1,ZNF44,GBX2,GRM1,SOX21,MDFI,PBX1,ENPP2,RETREG1,PROX1,PTPRB,KHDRBS2,RGS7,CCDC25,FAM102A,FRMPD1,SLN,MYH15,IFT122,SOX2,ASTN2,IQCE,TRIM2,GPR161,THRA,RUNDC3B,ZMYND8,NUP214" Drug 4343_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "APBB1,ARRB2,PDE8B,NRG2,SH2B1,NCOR2,SLITRK5,SPOCK2,SRGAP3,ATN1,EEF1A2,FEM1B,CNNM1,EGFR,KIAA1109,FGFR1,PRELID3A,GABRA2,GAP43,GPD2,GPER1,HLF,IL6ST,INPP5B,VWA5A,LSS,MEF2C,ZNF862,NTRK2,NUCB1,OGDH,RETREG1,EPN1,C1orf54,RASA3,PPP4R3A,MAPK8IP3,ZEB1,PCDHA5,GPR161,TRIO,OSBP2,VLDLR,ZNF711,PHTF2,SENP7" Drug 494_UP fluphenazine dihydrochloride; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "ASIC1,NDRG3,NDRG2,AMT,ASCL1,ATP2B1,CFAP410,CHRNB2,LHX2,DPP6,IRAK4,DCTN2,RASL10A,TBR1,OGA,GAD2,GPD2,LILRA2,CACFD1,SOX21,NXPH3,NCKAP1L,HMGCR,IGF1,KCNJ9,AFF1,NPTX1,OXTR,PALM,EPN1,SLC6A15,NUDT11,SYNDIG1,GALNT10,ASRGL1,RASA3,FBXO11,SNAP25,MAPKBP1,SPART,EXOC7,TNNT1,TST,FLRT1,SPHK2,LAS1L" Drug 2563_DN Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.09E-03 1.00E+00 1.30E-02 1.48E-01 46 193 "GRAMD1B,MRTFA,APBB2,ARRB1,CDK13,SLC4A4,ADAM15,LDLRAD4,PLAA,RCHY1,CREM,DBN1,SMG7,NR1D2,RCAN1,FCF1,GPHN,CD320,PDLIM5,GART,GNG3,IL6R,MEF2C,AFF1,PPP5C,SIDT1,DEF8,ZSCAN32,TMEM231,ZDHHC14,EXD2,GALNT10,SH3BP2,EMC1,DDN,NXT2,NCDN,MLC1,DMXL2,NSD1,CDK20,ELP5,TSN,XRCC4,ZNF74,LAMP5" Drug CID006450346 ganglioside GD2 Stitch 2.09E-03 1.00E+00 1.30E-02 1.48E-01 15 44 "CD81,CYBB,BOC,ENO2,FCGR3A,B3GAT1,B4GALNT1,MAG,KITLG,MYCN,NCAM1,PAX6,ST8SIA1,SOX2,CNTN2" Drug ctd:C419410 "N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester" CTD 2.09E-03 1.00E+00 1.30E-02 1.48E-01 15 44 "APP,NUMB,CDH2,CSF1,ENO2,TUBB3,FOXO3,FLT1,HMGB1,RBPJ,ITGAM,MAP2,HEY1,TLR4,HEY2" Drug CID000001688 Ro 5-4864 Stitch 2.09E-03 1.00E+00 1.30E-02 1.48E-01 15 44 "CACNA2D1,CBR1,AIFM1,DBI,ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,SLC6A7,ZEB1,ZNF384,HPS4" Drug CID000325714 NSC294864 Stitch 2.11E-03 1.00E+00 1.31E-02 1.49E-01 22 75 "KLRC4,FZD9,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CACNA2D1,GAL3ST1,VCAN,GREB1,GTF2IRD2,CSPG5,HAS2,TTYH2,VWA5A,NCF2,PDYN,TACR1,DNMBP,CYB561A3,TNNT1,CLIP2" Drug CID000002393 WP631 Stitch 2.11E-03 1.00E+00 1.31E-02 1.49E-01 22 75 "DPF1,SEMA6A,BMPR1B,CALB1,CALB2,NOG,PCYT1B,GAL3ST1,SLC32A1,GPHN,GAD1,GAD2,MYCN,OMG,GPSM2,PTPRN2,TCEA1,AMACR,PORCN,HPS4,SLC17A7,SLC17A6" Drug CID000002464 NSC89595 Stitch 2.12E-03 1.00E+00 1.31E-02 1.49E-01 18 57 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,NCOR1,ERCC2,PTK2B,FOXG1,ITGAM,PIK3C2A,PIK3CD,PIK3R1,MAPK3,MAPK4,MAPK7,RNASE1,TIAM1,UBC" Drug CID000004498 nipecotic acid Stitch 2.12E-03 1.00E+00 1.31E-02 1.49E-01 18 57 "ABAT,SLC32A1,GDA,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GLRB,GRIK1,SLC6A1,SLC6A11,SLCO1A2,SLC17A7,SLC17A6" Drug ctd:D016291 Dizocilpine Maleate CTD 2.12E-03 1.00E+00 1.32E-02 1.50E-01 25 89 "ADORA3,APP,CAMK2A,CCK,AIFM1,CNR1,DLG4,DRD1,PPP1R1B,GAP43,GFAP,GRIA1,GRIN1,GRIN2C,MAPT,NEFM,ENPP2,PENK,PRKCG,MAPK3,PRODH,PTN,SST,TAC1,AHCYL2" Drug 2854_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.12E-03 1.00E+00 1.32E-02 1.50E-01 45 188 "ADORA1,NME5,PLA2G4C,MARK4,ATM,CFLAR,CACNA1I,CA4,SPAG9,SLC16A4,SYNGR3,ZFYVE9,FADS2,COL9A2,LRIG1,VCAN,DOCK4,DBT,ATN1,KIAA1109,FGFR1,FHL1,TRAF3IP2,MSL3,TDRKH,MIA2,ZNF862,NDUFA5,PLCD1,PACSIN1,PRKAR1B,MAPK10,CCDC40,RAD52,SLC25A36,SEC14L1,SH3BP2,RPH3A,PEX26,KDM4C,THSD1,TK2,ZKSCAN5,UBE3A,PRDM2" Drug 7466_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.12E-03 1.00E+00 1.32E-02 1.50E-01 45 188 "APAF1,ARHGDIG,ARRB1,CDK13,SLC4A4,ATP2B2,MPDZ,ST3GAL5,SCAPER,BAIAP3,CACNA1D,CBFA2T2,SCARB1,NEURL1,RCBTB2,QKI,MFAP3L,MBNL2,MRNIP,VPS13B,ACSL4,FGF12,BAIAP2,FHL1,C1orf61,OGA,ZNF44,GNAS,KCNH2,MAP4,MDM4,MPP2,PRKAR1B,PTCH1,RIPOR1,RAB3IL1,GSTCD,ELOVL4,STX1A,COBL,WWC1,TRIM2,ARHGEF12,TRPC1,EPM2A" Drug 4010_UP Azacytidine-5 [320-67-2]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.12E-03 1.00E+00 1.32E-02 1.50E-01 45 188 "AMH,SEMA7A,AQP6,CDC14B,PPP4R4,BMP7,BAIAP3,GPR37L1,PLEKHB1,CLU,AKAP7,CREB5,AKAP12,IPCEF1,CTH,CTNND2,SPOCK3,BAIAP2,PRELID3A,GAB1,GABRA2,HAS2,HPSE2,ICA1,ITGA7,KCNF1,KCNQ3,NF1,PALM,CAMKV,PTHLH,PTH1R,C1orf54,RGS4,SFPQ,SLC11A1,MAPK8IP3,ARC,SLC44A1,TMOD1,TPM2,TPM3,TRO,SEMA3B,CAMK1G" Drug CID000198428 PDE I Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "ADORA1,ALDH7A1,CALM1,KRIT1,RGN,NAP1L2,PDE2A,PDE3A,PDE3B,ENPP2" Drug CID006327609 amino nitrate Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "NPIPA1,NRG2,SPEG,KCNH1,NBL1,RDX,ZNF365,TNNT1,WIPF2,NUP214" Drug CID000003452 gamma-acetylenic GABA Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "ABAT,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,MLST8" Drug CID000016546 tropolone methyl ether Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TBL1X,TUBB2A,TUBB1,TUBA1A" Drug CID000122222 DALDA Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "ATP6V0A1,DMTN,DNER,GFER,HNMT,OPRL1,PDYN,PENK,PIK3C2A,SHD" Drug CID000001547 2-chloro-N6-cyclopentyladenosine Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "ADARB2,ADORA1,ADORA2A,ADORA3,GRM2,GRM3,PTPN5,HP,HPR,P2RY1" Drug CID000009034 methohexital Stitch 2.13E-03 1.00E+00 1.32E-02 1.50E-01 10 24 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MAPK3" Drug CID000000401 L-cycloserine Stitch 2.15E-03 1.00E+00 1.33E-02 1.52E-01 20 66 "ABAT,MIER1,ARSE,KSR1,TOX,DOCK2,GALC,GLRB,GPT2,GRIA1,GRIA2,GRIK1,GRIN2C,GRIN2D,MSRA,OGDH,CNTN3,SHMT2,SLC6A9,FTSJ1" Drug CID000104826 resiniferatoxin Stitch 2.15E-03 1.00E+00 1.33E-02 1.52E-01 20 66 "ASIC1,ASIC3,CST3,SYT17,ATP8A2,IGFBP1,MAT2A,NAP1L2,ABCB1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TAC1,PRRT1,ZIC3,ST8SIA2,GAN" Drug CID000447409 T-C-T Stitch 2.15E-03 1.00E+00 1.33E-02 1.52E-01 30 113 "ABHD6,AXIN2,BRAP,ADRB2,APC,ATM,BLM,CHM,QKI,COL4A5,GAL3ST1,TOX,DCT,SACS,ACOT8,F3,GAA,HPGDS,NR3C1,PTGDR2,MAP4,MBNL1,NCAM1,SERPINI1,SALL1,TET1,GPR161,HHIP,TTPA,PCBP4" Drug 7507_UP daunorubicin HCl; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.15E-03 1.00E+00 1.33E-02 1.52E-01 44 183 "ABR,APC,APLP1,PRX,CFLAR,BMP7,P2RX6,RCBTB2,SLIT2,DNAJB5,WHRN,ABCG1,DMPK,MED12,F8,FGFR3,DPYSL4,SYT17,ALDH1L1,SESN1,GLS,AGBL5,IL6R,INPP1,MITF,NPTX1,PDE4A,PPP2R2B,SNRK,TMEM231,RALGDS,C1orf54,RAP1GDS1,IL17RB,ZNF821,SLC6A8,SNCA,SOX10,SS18,ELOVL4,ARC,ATP13A2,ZMAT3,ZNF34" Drug CID000000305 choline Stitch 2.16E-03 1.00E+00 1.34E-02 1.52E-01 70 320 "ACHE,ABHD6,PLA2G6,APC,GPAM,ATP1A1,ATP1A2,ATP1A3,ATP1B3,BCHE,CA4,CA8,CA12,CACNA2D1,CALB2,SPAG9,CBS,CHRM1,CHRNA4,CHRNB2,PCYT1B,ABCG1,PLCXD3,PNPLA8,HEPH,ENPP6,ST3GAL6,PSD2,GAD1,GAD2,GFAP,GPT2,GRIA2,PLCD4,GRIK1,TNFAIP8L3,KCNN1,MAT2A,AQP11,MTR,NEUROD1,NPPA,ENPP2,PLCB2,PLP1,PLTP,PPARA,PTCH1,RAB3A,SMPD3,SEC14L1,SLC6A1,SLC6A11,SLC12A4,SLC22A4,DDN,ADHFE1,VPS13A,PLCB1,SYT1,SLC44A1,SMUG1,TRH,CA14,HEPACAM,PLPPR5,SLC30A4,PLD4,SLC17A6,GJC2" Drug ctd:D008628 Mercury CTD 2.16E-03 1.00E+00 1.34E-02 1.52E-01 118 585 "RALGAPA1,SERPINA3,ACHE,ARID1A,AP2A2,ALAD,CARNS1,ANK1,GAS7,ALS2,APP,AQP4,ZBTB10,ATP1B3,AZGP1,BLM,CDK5R1,IL33,FOXK1,DIRAS1,SCARB1,LRRFIP1,CLGN,SLC22A6,PPT2,NMT2,CLTC,ABCG2,CP,ABCG1,SEC24C,PDE4DIP,HEPH,PLPPR4,DTNA,EIF4G1,SRPK3,USPL1,EMX2,EZH1,F5,NSRP1,FABP7,RPS6KC1,FCGR1A,FCGR3A,FECH,DPYSL4,CSPG5,FAM184B,TUBA8,TOX3,MSL3,OS9,LILRA2,GPER1,GSN,MAN1B1,KLF12,HSF2,HSPA1L,HSP90AA1,IRF8,IGF1,JAK2,KCNH2,MSR1,PTOV1,MT1M,MT3,SCG3,MTR,NAP1L1,NFE2L2,SLC11A2,NTRK3,OGG1,PDE1A,ABCB1,PIK3R1,PLXNB3,PPP3CB,PRKCG,MAPK3,RELN,DEF8,ANKHD1,ARID4A,ZFHX4,IL17RB,SH3BP2,DOCK10,LIMS2,SLC11A1,SLC12A2,SLC22A4,SPP1,CLASP2,TAC1,PCDHB4,TNS2,HIF3A,TF,ITGB3BP,TK2,TPM2,TST,CADM1,GORASP1,ZBTB38,ZBTB16,SH3GLB2,CADM2,NAV3,MVB12B,RTN4,NLRP3,FRMD6" Drug CID000003337 fenfluramine Stitch 2.18E-03 1.00E+00 1.35E-02 1.54E-01 43 178 "ASIC1,ADAR,ADRA1B,LRRC4C,CCK,ASIC3,CHRM1,DCT,DNAH9,OPTN,CD320,TUBB3,FGR,GAD1,GAD2,MALT1,LOXL3,GPD1,GPD2,TNFAIP8L3,HTR2A,HTR5A,IGF1,IGFBP1,MAOB,NPY,PDYN,PENK,FTO,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,SOX10,TROVE2,SST,TAC1,ZFP91,TRH,TUB,PLPPR5" Drug ctd:C016601 afimoxifene CTD 2.19E-03 1.00E+00 1.36E-02 1.54E-01 99 479 "CLK4,AK2,ALAD,BCAR3,ANK3,SHROOM2,TMEFF1,ASCL1,MARK4,NCOA1,DDX3Y,DYNLL1,BMP7,CA12,COPB2,SLIT2,NCOR1,ABCG1,GREB1,ECE2,MATR3,RHOBTB1,AK5,FAM107B,ARNT2,RPS6KL1,DRD1,ABCC5,RASGRP1,EGFR,EGR3,EIF5,EPS8,ERBB2,STRADA,OLFM1,CAP2,FLNC,FLT1,NOP56,NRG3,SESN1,PPARGC1A,RND1,CBX1,LNX1,GPER1,ELOVL5,HMGB1,IGF1,IGFBP1,JAK2,KHK,STMN1,MMP16,NEFM,NME4,NPR2,PCDH8,PMP22,SCHIP1,FA2H,TATDN3,PRKCZ,MAPK3,MAPK8,MAPK9,PRODH,PTHLH,ELOVL2,RET,CLIP1,RXRA,MAPK12,SELL,ZNF821,SFPQ,FAM102A,CLSTN1,NBPF1,SMTN,COA1,FAIM2,SON,TRERF1,SYT1,TACC1,TAF9,WWC1,TCF7L2,ZEB1,TMPO,NEIL2,SGK3,MEAF6,XPO1,DHX33,FRMD6,ST8SIA2" Drug CID000071273 S-ropivacaine Stitch 2.20E-03 1.00E+00 1.36E-02 1.55E-01 14 40 "ASIC1,TKTL1,ASIC3,TRAPPC9,OGA,ATP8A2,KCND3,KCNH2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug ctd:D013779 Tetrodotoxin CTD 2.20E-03 1.00E+00 1.36E-02 1.55E-01 14 40 "ENTPD4,CYBB,PPP1R1B,GRIA1,GRIA2,KCNC1,KCNC2,NPY,PRKCB,SCN2A,SCN2B,SCN3A,SCN8A,ARC" Drug CID005281614 fisetin Stitch 2.20E-03 1.00E+00 1.36E-02 1.55E-01 14 40 "CRLF1,FADS2,DNM1,CASP8AP2,FARSB,PNMA2,ALDH1L1,GPD2,PTPN5,CD200,MTR,PSAT1,POU3F4,SIRT1" Drug CID000024766 chondroitin sulfate Stitch 2.23E-03 1.00E+00 1.38E-02 1.57E-01 87 413 "ALCAM,APLP1,APP,ARSE,PROM1,DST,GPC2,MYOM2,CDH2,NOG,B4GALT6,COG1,CNTN1,COL4A5,COL9A1,COL9A2,COL9A3,COL11A2,HAPLN1,CSF1,VCAN,NCAN,SDC3,ARHGEF4,KIAA0586,SPOCK2,B3GAT3,SPOCK3,NTM,ELN,OLIG2,EXTL2,F3,FABP7,ACSL4,FGF1,CSPG5,B3GAT1,OGA,CHL1,GALC,B4GALNT1,MYOZ2,NEU3,GFAP,LYVE1,HAS2,HMGB1,ATCAY,ITIH2,L1CAM,MAG,CHST6,MMP16,MMP17,MOBP,MOG,RSPO2,NCAM1,NCAM2,OMG,SERPINE2,SEMA5B,PLXNB3,PTN,PTPRB,PTPRZ1,SELL,FNDC3A,BCAN,NLGN1,SLC1A3,SPP1,CLSTN2,ITPRID2,THSD1,CNTN2,NEU4,CHST8,TGFBR3,HHIP,THBS4,TNR,CHST5,ADAMTS9,RTN4,NETO1" Drug CID000327966 AC1L71LN Stitch 2.25E-03 1.00E+00 1.39E-02 1.59E-01 33 128 "ASIC1,APLP1,CDK5R1,PRC1,CBS,CHGA,ASIC3,HP1BP3,DRD1,FCGRT,PPP1R1B,TPK1,CBX1,IL12A,SCG3,NEUROD1,PCSK1,PCSK2,PENK,PKD1,POU3F4,PTPRN,SCG5,SLC12A2,SST,SSTR1,STX1A,SYT4,ALG1,TK2,TRH,TRPC1,SCG2" Drug CID000452307 A-74702 Stitch 2.26E-03 1.00E+00 1.40E-02 1.59E-01 23 80 "C1QTNF3,BMPR1B,RUNX1T1,PLEKHB1,ZFYVE9,NCOR1,NCOR2,HDAC9,MED12,BRD8,GPR37,HMX1,KCNJ5,PACRG,RORB,LRRK2,RXRA,RXRG,SAFB,SST,SSTR2,THRA,ZBTB16" Drug CID000051605 fenoxycarb Stitch 2.26E-03 1.00E+00 1.40E-02 1.59E-01 23 80 "CALB1,CALB2,CAMK2B,CHRNA4,CHRNB2,DMPK,FOXG1,GBX2,KCNA6,KCNN1,KCNN2,KCNN3,NAP1L2,NPY,NUCB1,PCSK2,PLCB2,LRP12,TMEM132D,NPL,ZIC1,PRDM2,HPS4" Drug CID000005358 sumatriptan Stitch 2.26E-03 1.00E+00 1.40E-02 1.59E-01 23 80 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,CACNA2D1,P2RX6,LPAR6,B3GAT1,CRCP,LOXL3,LPAR4,HTR2A,HTR5A,MAOB,P2RY13,P2RX7,P2RY1,CCDC88A,TACR1,P2RY12" Drug CID000002399 BiM4 Stitch 2.26E-03 1.00E+00 1.40E-02 1.59E-01 63 283 "ADORA1,ADORA2A,ADRA1B,AGT,APP,CFLAR,CALM1,AIFM1,LRBA,NUMBL,CHRM1,CHD1L,HDAC4,MAML1,EDN1,EDNRA,EDNRB,CELSR3,EGFR,PTK2B,GPR162,RAPGEF4,GRIN2C,GRIN2D,GRM1,GRM2,GRM5,GRM7,GRM8,HTR2A,IGF1,ASPRV1,NTRK2,KCNK10,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PSD,PSMA6,PTHLH,PTK2,RPS6KA2,MAPK12,SLC1A2,SLC1A3,SLC20A2,RIMS1,PLCB1,VAV2,PLD4" Drug CID000004375 FG 7142 Stitch 2.28E-03 1.00E+00 1.40E-02 1.59E-01 13 36 "ABAT,CCK,CCKBR,DBI,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HTR2A,TACR1,ZEB1" Drug CID000013165 hydroxyethyl acrylate Stitch 2.28E-03 1.00E+00 1.40E-02 1.59E-01 13 36 "TKTL1,KDM5D,AMT,TNK2,F8,GPR162,MCHR1,MAG,KITLG,SCN2A,TRERF1,TCF12,TTC7A" Drug CID000001676 enprofylline Stitch 2.28E-03 1.00E+00 1.40E-02 1.59E-01 13 36 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,PDXK,ALDH7A1,P2RX7,PDE4B,BEX1" Drug CID000159325 torcetrapib Stitch 2.28E-03 1.00E+00 1.40E-02 1.59E-01 13 36 "APOC1,SCARB1,ABCG1,FDFT1,HMGCR,MTTP,GPR85,PLTP,PPARA,SLC12A4,TNFRSF1B,P2RY12,NETO1" Drug CID006398525 Sulcrate Stitch 2.28E-03 1.00E+00 1.40E-02 1.59E-01 37 148 "SERPINA3,ACLY,ADRB2,OGT,APAF1,APLP1,APP,AZGP1,BCHE,NGB,TBPL1,PLCXD3,ARHGAP32,BSCL2,TUBA1B,PTK2B,DNER,CYP46A1,GNAL,GNAS,GNG3,GPT2,PLCD4,HBA1,HRH3,NEFM,NEFH,P2RX7,PDE1C,PDE1B,PLCB2,QDPR,SST,PLCB1,TBL1X,TF,PLD4" Drug 1135_UP minocycline; Up 200; 10.5uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADD3,AK2,ALAD,APP,NUMB,FUBP1,RAB26,RNF14,TBC1D5,INTS1,TRAPPC9,DTNA,TNK2,PCOLCE2,BAIAP2,ZNF44,GART,SRCAP,RAB40B,BTN2A1,HSF2,ICA1,KCNJ3,NF1,PRKACB,VPS13C,PTPRG,FBXW7,LGR4,MAPK12,ATXN1,ITSN1,ABLIM3,GLT8D1,NCDN,DNMBP,TBL1X,EHBP1,RBFOX2,TPD52,TRIO,ZMYND8,HIRA,VGF,WRN,FIP1L1,MPPE1" Drug 5875_DN Gabapentin [60142-96-3]; Down 200; 23.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADRB2,MTUS1,AMT,APBB2,DGKD,APP,MARK4,MTMR9,IQCK,ARMC8,NRG2,VCAN,CNTNAP2,HDAC9,DAPK3,FBXL5,C2CD2L,EIF5,ERCC2,ZNF589,FGF13,INPP5K,AHDC1,MAP4K5,MUM1,L1CAM,MAN2A2,MAPT,MBD1,SCAMP5,TAGLN3,LRP12,POLG,SH3TC2,TMEM156,SH3BGR,ST6GAL1,EPN2,RAB3GAP1,SCMH1,ERC1,ZBTB43,NXT2,XRCC4,VPS35L,NAV3,KAT6A" Drug 1892_UP Levodopa [59-92-7]; Up 200; 20.2uM; PC3; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,PLA2G6,ATM,CADM3,ATP6V0A1,BTRC,KIAA1549L,DNAJB5,TOX,KLHL3,PARD6A,RABGAP1L,DTNA,EFNB3,EPB41L1,OLFM1,AFF2,ATP2C1,SRCAP,ARFIP1,PCDH17,ADAMTS13,KLF12,MAP4,TAGLN3,MYO9A,NAP1L1,NPPA,NTRK3,PTPA,RAB3A,ATXN2,IL17RB,ANKRD6,SLC1A7,SLC11A1,DOK5,SPTB,FCHO1,MCF2L,TCF7L2,SEZ6L,TRPC1,VIPR2,LAT2,MPPE1,SMIM8" Drug 2755_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,SPARCL1,APC,APLP1,PPFIA3,ASPH,N4BP2L1,GYG2,CACNA1I,CACNA2D1,RCBTB2,HOMER3,AKAP7,SLC4A7,PHF14,MAGI2,KBTBD11,EFNA3,EGFR,ERCC2,ZNF589,FHL1,POLL,ATF7,TDRKH,GPR22,GPER1,ICA1,IL6ST,KCNF1,KIT,NF1,OGG1,MINDY2,ZDHHC14,TRIM68,RGS3,UEVLD,FOXRED2,SH3BP2,KIF16B,PKNOX2,FCHO1,POPDC3,RBFOX2,ZNF45,EPM2A" Drug 2933_DN Decamethonium bromide [541-22-0]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ARID1A,NDRG3,PPFIA4,PPFIA1,APAF1,APC,BACH1,OSGIN2,SLC25A14,CAPN3,ENTPD6,EPS15L1,TPP1,NIPBL,HOMER3,CSF3R,DZIP3,VPS26C,F8,FHL1,TRMO,ERAP1,USP19,PRRC2B,INPP1,CCSER2,RC3H2,MINDY2,PTPA,SIDT1,PTPRN2,BSDC1,RET,DOCK10,FUZ,WDTC1,TNIK,CDK19,ZC4H2,SYT11,TACC1,EXOC7,TRPS1,UBE2H,FLRT2,ATP6V0E2,PRDM2" Drug 6804_UP Midodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "SEMA6A,CDC14B,MARK4,CFLAR,BAIAP3,CA4,NFS1,STOML1,CLTB,VAX2,CNTN1,RIMS2,JAKMIP2,DNM2,ST8SIA3,EFNB3,STX2,REEP2,TDRKH,TJAP1,ITGAM,ITIH2,IPO5,VWA5A,MBD1,MDFI,ZNF862,CDIP1,KLHDC8A,TCP11L1,EMID1,PPP1R9A,ASAP3,FAM214B,SLC11A1,BEX1,SPTB,TROVE2,INKA2,STX1A,ZNF34,UBE3A,UCHL1,VIPR2,WIPF1,SLC17A7,KCNAB1" Drug 3994_DN Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AMPD3,BIN1,KCNAB2,APC,GAS7,APP,LGR5,MADD,NRP2,CFLAR,ARHGEF1,SEPT7,FOXN3,CHI3L2,LHX2,DNAJB5,WHRN,AATK,CNTNAP2,EDRF1,BRINP1,ATN1,FAM13A,MRNIP,LRRC23,DENND4A,GUCY1A2,SHISAL1,PBX1,EPN1,PTPRB,RAB3IL1,RGS4,ARHGEF10L,SUGCT,FRMPD1,FBXO11,SLC6A9,SMARCD3,SNCA,KDM4B,SYN2,SYT1,GPR161,RPRM,EVI5,KCNAB1" Drug 6244_DN Hexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "APBB2,APC,MADD,ALDH4A1,ATM,EIF4G3,CFLAR,SYNJ2,SLC4A8,PDE4DIP,DNM1,DTNA,SIDT2,IRAK4,CDKL3,F8,FGFR1,FHL1,DPYSL4,TRMO,MSL3,KCNMB4,DIDO1,KHK,MAP4,MAPT,NEK1,PRPH,LRRC49,RIPOR1,TMEM231,RAB3IL1,FAM184A,ZDHHC14,ROBO1,SCMH1,ZKSCAN3,UNC5B,ZBTB43,TROVE2,CAMTA2,ANKRD28,ANKRD12,OBSL1,PARD3,TRPC1,NDRG4" Drug 2187_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "SLC12A5,BIN1,CDC42BPA,CDC14B,CDK10,ARSE,TAOK2,ZFYVE9,HOMER3,CNR1,RCHY1,CREM,DAPK3,SORBS3,LRRC17,CDHR1,ATP8A1,DCTN2,KHDRBS3,DENND2A,ATP8A2,INPP5K,NEU3,GLYR1,ACOT7,KIT,MAP4,AFDN,CD200,NNAT,SLC25A23,DCHS2,CNNM2,KLHDC8A,STUM,SH3BGR,ITSN1,SLN,SNCA,SPTB,VAMP1,SYN2,WSCD1,TPM1,TRPC3,FLRT2,PAK5" Drug 1203_DN haloperidol; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,MTUS1,CDC42BPA,APP,MARCH3,BCHE,WASF1,CA12,ARMC8,TENM4,SNPH,LYPD1,TRAPPC9,EFNA3,SPEG,EZH1,SCML2,FGF1,POMT1,CGREF1,GBX2,AHDC1,GLRB,MAP4,SCAMP5,SETD4,PAK3,PC,LRP12,PTPA,PPP5C,RAP1GAP,SEC61A2,ASAP3,CCDC88A,SNCA,ZBTB43,SPART,ELOVL4,STX1A,TK2,CLIP2,TRIM9,NDRG4,EPM2A,FZD3,ST7" Drug 1964_UP Cimetidine [51481-61-9]; Up 200; 15.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACTN1,PPFIA1,DGKD,CDK10,ARRB2,BMP7,CHRNB2,ZFYVE9,CHD1L,KIAA0753,ABI2,BSCL2,CD320,MPP6,ZNF44,TXNL4A,GLYR1,DIDO1,GRIK5,MAN1B1,JAK2,NRGN,PDE4D,ENPP2,GPSM2,PLCD1,GON4L,PTK2,BSDC1,RDX,SGK1,ITSN1,CCDC92,FAIM2,KDM4B,FNBP1,POGZ,NSFL1C,PDLIM2,DMXL2,TK2,ZKSCAN5,PLPPR2,FIP1L1,MARCH8,ZNF248,AAAS" Drug 3073_DN Flucytosine [2022-85-7]; Down 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "C1QTNF3,CDC42BPA,APAF1,SCAPER,HIP1R,B4GALT6,PDE4DIP,PLXNC1,EIF4G2,EIF1,VPS13B,KIAA1109,PDLIM5,GABRA2,GPD2,PCLO,IL11RA,N6AMT1,NINJ2,PLTP,PRKCZ,MAPK8,CNTLN,PTN,BEND5,MYH14,RXRA,SEC14L1,FAM214B,TMCC1,WDTC1,ZHX3,SPTAN1,CDK19,KANK1,ATP11A,KAZN,CAMSAP2,ADGRL3,TBL1X,FLRT2,PLPPR2,XRCC4,MKRN3,PRDM10,UBE3B,NLRP3" Drug 5725_DN Ricinine [524-40-3]; Down 200; 24.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RALGAPA1,AP2A2,BIN1,ALDH7A1,CA8,B4GALT6,SULT4A1,TCEAL2,CREB5,HAPLN1,PARD6A,EIF4G2,EPHA5,CINP,CSPG5,OGA,FYN,ERAP1,GPD2,TDRKH,KLF12,LIFR,MAPT,NPR2,CCSER2,GRAMD1C,RAB3IL1,SH3TC2,RPS6KA2,SBF1,SH3BP2,ASAP3,FUZ,SNCA,SS18,SYT11,TCF7L2,SZT2,CHST8,TIAM1,UGT8,WIPF1,KLC2,XRCC4,KCNAB1,MPPE1,ACTR3B" Drug 6086_DN Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "PLA2G6,APBA2,GYG2,BTRC,CACNA1D,KYAT1,CLU,NECTIN3,SH2B1,CSF1R,LRIG1,RIMS2,MFAP3L,TMCC2,EGFR,ING4,C3orf18,F3,C1orf61,OGA,RASSF8,INPP1,INPP5B,ITIH2,KCNMA1,VWA5A,MID1,MSI1,NF1,GRAMD1C,PRPH,PTN,ZSCAN32,RGS10,SEMA6D,PREX2,MAPK8IP3,SYN2,KAZN,MCF2L,AHCYL2,TMOD1,CABIN1,ZMYND8,VGF,VIPR2,WNK1" Drug 6755_UP Mitoxantrone dihydrochloride [70476-82-3]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACHE,NR0B1,BRINP2,B3GALT2,CA4,CACNG1,KALRN,CAMK2B,CDC42,EPS15L1,ABCG2,ARHGEF4,RIMS2,SEC14L5,RIMS3,ATN1,ING4,FOXG1,SIGLEC8,RUNDC3A,PRUNE2,GPM6B,GRIK3,HTR2A,SHISAL1,KCNH1,MAG,ADAM22,P2RY13,P2RY1,PALM,TMEM231,MARCH1,CCDC40,ENOX1,SCN3A,FRMPD1,DZIP1,SLA,SLC2A5,ATP10B,SYT5,SEZ6L,RUNDC3B,UBE3A,FLRT2,NLRP3" Drug 3205_UP Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG2,SPARCL1,CCDC181,SYNJ2,GYG2,CACNA1D,CBFA2T2,SLC4A7,BAG4,MYRIP,CNTNAP2,PPP1R16B,ARHGEF4,NOS1AP,BRINP1,DUSP9,ST8SIA3,ING4,ERCC2,EXTL1,ATP8A1,GPR75,GUCY1A2,KCNJ5,AFDN,ADAM22,ZNF426,PPP5C,GAL3ST4,RGS4,EPN2,SMTN,OGDHL,RBM34,ZHX3,RBM26,ATP10B,EXOC7,ADGRL3,ARHGEF12,CRTC1,SLC35G2,GPR161,TMOD1,CABIN1,VAV2,CLIP2" Drug 7373_DN Nitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ABR,AP2A2,APBB2,APC,ALDH4A1,MYRF,NIPBL,AKAP7,CREM,SGSM2,DLG3,DYNC1I1,COQ7,ERBB2,ETV1,TRMO,GAD1,GNAS,INPP5B,KIF5C,ARHGAP12,MBD1,NAP1L1,PAK3,PDGFRA,PIK3R1,PLCD1,POLG,FSD1,SYTL2,SNRK,PTN,RAB3IL1,GTDC1,SFPQ,FAM102A,KIF16B,AMBRA1,LIMS2,TMCC1,FCHO1,RGL1,FAM168A,ZNF34,ZBTB14,TRIM9,RNF170" Drug 3638_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,BIN1,CDC42BPA,KCNAB2,APC,APOC1,GYG2,CACNA1I,BAIAP3,HAP1,CDO1,AKAP5,SNCAIP,SIPA1L1,CNTNAP2,DAPK1,MFAP3L,SHANK1,ZNF589,FOXG1,DLL3,C1QL1,GSN,DHX35,ICA1,KCNH2,ADAM22,NDUFA5,NEK1,NPTX1,CDK18,RETREG1,EPN1,RAB3A,RAD52,SLC1A2,CXXC4,WDTC1,DOK5,KDM4C,RPGRIP1L,ARHGEF12,CRTC1,SLC35G2,PIK3R5,PRDM2,ITM2C" Drug 3344_DN Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AK2,MRTFA,APBB2,APLP1,APOC1,PLA2G4C,ASPH,CA12,CBFA2T2,RCBTB2,CLU,CRY2,ARHGEF10,GIT2,DNM2,SLC12A6,CELSR3,SORBS3,FER,BAIAP2,SEMA4D,ANKFY1,HBS1L,RAB30,MAP4,ADAM22,NPTX1,PDE3B,PRKAR1B,ZSCAN32,ROM1,TCP11L1,SYBU,EPN2,ZBTB43,SUPT5H,ATP11A,SEMA4A,SZT2,CDK20,ZKSCAN5,VAV1,VAV2,ZNF45,WNK1,HPS4,SSPN" Drug 5928_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ABR,MTUS1,C1QTNF1,LTBP4,PPFIA1,APBB2,CDK10,CDC42,ASIC3,CHRNB2,ARHGAP22,NIPBL,IFFO1,SMARCAL1,DUSP9,EDNRA,EFNA3,ING4,STX2,SCML2,ANKFY1,PRELID3A,TMEM8B,TXNL4A,POLL,GPER1,BACH2,HNMT,KHK,MAPT,PLCB2,PPP5C,PTHLH,BEND5,GTDC1,IL17RB,KIF16B,SLC1A7,SLC15A2,DDN,NXT2,ARHGEF9,TNS1,TRIO,VGF,WIPF1,SMIM8" Drug 1863_UP Mefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,OSBPL1A,APC,APOC1,DNAH17,NCOA1,KRIT1,SLC16A4,CDC42,RAB33A,CLCN3,CLCN4,IQCK,ZFYVE16,GIT2,SGSM2,MRNIP,EIF1,ENO2,RASGRP2,ANKFY1,EFCAB2,VWA5A,N6AMT1,NF1,PIK3R1,CDIP1,CEP41,CNNM2,GSTCD,TRA2B,RASA3,ITSN1,TMCC1,WDTC1,CDK19,THSD1,ZC4H2,KAZN,TBCEL,SIN3B,ATP13A2,DICER1,TK2,RBFOX2,BCL2L13,PRDM2" Drug 6036_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "MTUS1,KCNAB2,APOC1,ASPH,MTMR9,BTRC,KRIT1,CBFA2T2,SRSF11,NMT2,FEZ1,DAPK3,MFAP3L,DTNA,ABCC5,EDNRA,ENO2,VPS26C,GALC,GART,USP19,GLYR1,MAP4,MEIS2,MMP16,CNOT4,PDE3B,SERPINE2,LGR4,SEC14L1,SFPQ,FBXO11,SLC20A2,SLC22A4,EMC1,THSD1,MAPK8IP3,VAMP1,PLCB1,TACC1,EXOC7,TRIM2,ZNF34,KCTD2,RBFOX2,CDK20,UBE2H" Drug 5535_DN Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASPHD1,OGT,MARK4,SLC4A4,ST3GAL5,CACNA1D,AKAP7,ABI3BP,PDE4DIP,ARHGAP32,KIAA0586,GIT2,SMG7,TRAPPC9,CDON,EFNA3,IRAK4,PLEKHO1,EPB41L1,SEMA4D,HBS1L,INPP5K,GRB10,ARHGAP19,ITPKB,KCNF1,KCNJ3,NF1,NFYA,MINDY2,PPP5C,PRKAR1B,FOXRED2,SH3BP2,FUZ,AMBRA1,FAM214B,SCMH1,ZCCHC24,NXT2,ASTN2,TGFBR3,RBFOX2,TRIO,UBTF,PLPPR2,ZBTB14" Drug 6560_DN Gly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,NCOA1,ST3GAL5,MAP7,CHN2,DZIP3,PARD6A,ATN1,EDNRA,EDNRB,SGK2,PLEKHO1,PTK2B,TRAF3IP2,SIGLEC8,SYT17,GART,SRCAP,CRCP,GPM6B,GPER1,IL12A,INPP5B,ITPKA,PTN,TMEM231,FAT4,ZFP30,SH3BP2,ITSN1,PEX26,SNCA,KIF13A,WDTC1,BEX1,PBLD,COLGALT2,SEPT8,VPS13A,DNMBP,WSCD1,PSD3,TNS1,ZKSCAN5,MICAL1,MAP3K12,DPF3" Drug 314_DN sulindac sulfone; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "BIN1,KCNAB2,CDK10,ARNTL,ASCL1,BTRC,CBFA2T2,AP4M1,LHX2,ARHGEF6,DGKG,SIDT2,EML1,FGFR1,GPR153,GAB1,SRCAP,GPR19,PTPRT,SOX21,C2orf72,KCNJ3,KCNMA1,KIFC3,NOVA2,OPCML,PCSK2,SNX10,RGS4,RPH3A,SLC8A1,BTBD7,SNCB,ZHX3,ZC4H2,AJAP1,SYN1,TBL1X,TCF7,OBSL1,TEK,TPD52,FLRT1,GDPD5,KCNAB1,MARCH8,AAAS" Drug 1185_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RALGAPA1,ASIC1,TRMT9B,PPFIA1,GAS7,APP,SLC16A4,TPP1,DNAJB5,IQCK,HINFP,CSF1,PDE4DIP,SLITRK5,RIMS2,KIAA0753,DTNA,EGR3,MRNIP,EIF1,EPB41L2,NRN1,FOXG1,GAD2,ERAP1,INPP5K,ALDH1L1,RND1,GLYR1,NEFH,NINJ2,PIK3R1,PTAFR,TMEM231,KLHDC8A,PAQR6,TRAPPC13,SH3BP2,NTNG1,SPTAN1,RBM26,SS18,MAPK8IP3,PDLIM2,TNS1,WIPF2,PHTF2" Drug 3089_UP Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACTN2,BCAR3,AMPH,PLA2G4C,ATP2B2,MPDZ,GYG2,CACNG1,REPS2,RAB33A,NMT2,CNTN1,FAM149A,PDE4DIP,DBT,JAKMIP2,ERBB2,ANKMY1,EXTL1,DLC1,CGREF1,GPR153,ATP8A2,ZNF276,GLRB,GLS,ATXN2L,IL6ST,KCNJ5,GIT1,OMG,PDGFRA,SYTL2,ZSCAN32,PTPRH,KCNIP1,TRIM46,ST6GAL1,EPN2,SLC9A5,SLCO1A2,MYT1L,IQSEC2,CUX2,THRA,TJP1,SLC17A7" Drug 2232_UP Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "SYN3,APLP1,SYNJ1,CACNA1G,ASIC3,QKI,AKAP6,SPOCK2,DPP6,RCAN1,DTNB,ST8SIA3,SIDT2,TNK2,PTK2B,SORBS1,TPK1,OGA,GAD1,GAD2,GBX2,RND1,GRIA4,GRM8,KIF5A,ADAM22,NPR2,PCBP3,PDGFRA,PLCD1,PTAFR,TMEM206,SYNDIG1,RYR1,ITSN1,ASAP3,CPEB3,ST6GAL1,SLA,KDM4B,TSPYL2,SPART,VAMP1,DNAH7,CHST8,TPM2,HPS4" Drug 6088_DN Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASPHD1,APBA2,KCNAB2,APBB2,CAPRIN2,SYNJ2,CA4,CACNA1D,KYAT1,CBFA2T2,PLEKHB1,PLAA,NMT2,QKI,NECTIN3,CSF1R,C2CD2L,RABGAP1L,DLG3,DUSP9,PRELID3A,NR3C1,MUM1,RASSF8,PADI2,IPO5,MMP16,MSI1,MINDY2,PRKAR1B,CEP97,RGS12,WLS,SBF1,ANKRD6,SLC1A7,SMARCD3,EMC1,KDM4C,IQSEC2,THSD1,EXOC7,AP4E1,TMOD1,VIPR2,TFIP11,SEMA3B" Drug 2562_DN Isocarboxazid [59-63-2]; Down 200; 17.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,ABHD6,APC,CDK13,SYNJ2,CAMK2G,HOMER3,ARMC8,SIPA1L1,MAML1,CTIF,SPATA2,TRAPPC9,EFCAB2,PDLIM5,MSL3,MUM1,MAP4,SCAMP5,GIT1,OCRL,TMEM104,PTCH1,FAM120C,RAB3IL1,SEC14L1,GALNT10,MRAS,SH3BP2,LIMS2,MYH15,KDM4B,ZHX3,IZUMO4,SPTAN1,MAPK8IP3,DIP2A,EXOC7,TCF4,DMXL2,SZT2,TPD52,TPM2,ZMYND8,PLPPR2,WNK1,ACTR3B" Drug 3780_UP Proglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "DPF1,ADCY2,MRTFA,CDC14B,PDE8B,ASTN1,NRP2,FUBP1,BAIAP3,NMT2,INTS1,DAPK3,ING4,GATM,GNAL,GRIK2,RASSF8,NXPH3,KCNJ4,LAMA2,MAG,MMP17,NF1,NPPA,PCDH9,PDE4D,ENPP2,PGAM2,PNMA3,RGS10,PAQR6,RTN1,CPEB3,SLCO1A2,ZHX3,HECW1,ZC3H13,IQSEC2,SYT11,ADGRL3,SLC44A1,TMOD1,ZIC3,ZNF225,EVI5,NUP214,NLRP3" Drug 3674_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADCY2,NME5,KCNAB2,BRINP2,ALDH4A1,ADGRB2,MYRF,NEURL1,NRXN3,SULT4A1,COL9A3,ABCG1,SNCAIP,DYRK1A,PLXNC1,ELAVL4,FGF12,FGFR3,C1orf61,SIGLEC8,CSDC2,ADAMTS13,GRIN1,GRM3,ITGA7,MAPT,MSR1,PDE3B,DUSP26,PLXNB1,RFX2,SELL,STUM,RASA3,NTNG1,SLCO1A2,SNAP25,ZHX3,ATP10B,MAPK8IP3,VAMP1,PLCB1,ZFPM2,THRA,TRO,KCNAB1,SENP7" Drug 2683_DN nordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ABAT,BCAR3,PPFIA4,APC,SLC16A4,ARHGAP33,CLGN,ZFYVE9,AKAP7,NCOR2,SLITRK5,ARHGAP32,DAPK3,DYRK1A,ABI2,ING4,ELN,LRRC23,SEPT9,SRCAP,AHDC1,GLS,IFI16,TJAP1,MAP4,MAPT,NRGN,OLR1,PMP22,PPARA,PPP2R5C,SIDT1,GON4L,RAB3IL1,KHDRBS2,ZNF671,CCDC92,PPP4R3A,EPN2,ZHX3,EMC1,KDM4C,ARHGAP26,FCHO1,MAPK8IP3,NSD1,RBFOX2" Drug 6332_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,MRTFA,FAM131A,SHROOM2,CASK,C5,AP4M1,NIPBL,ARHGEF4,DCAF8,KIAA0753,LYPD1,SMG7,MED12,DYNC1I1,ABI1,ERCC2,SPEG,ATP2C1,DENND2A,GAD1,GPD2,GPM6B,ARHGAP19,KLF12,SYNPO,IL11RA,ITPKB,MAP4,OGDH,PIK3R1,LRP12,PTPA,SYTL2,BSDC1,AP1AR,SCG5,PPP1R9A,EPN2,SLC14A1,ELMO2,TMCC1,SP2,EMC1,TBL1X,TRIO,UBTF" Drug 6148_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "KIDINS220,AMPD3,CDC42BPA,PKP4,PPP4R4,ATP2A2,ARHGEF7,SGCE,BTRC,CAPN3,CDC42,NMT2,HOMER3,ENTPD4,CRMP1,PPP6R2,ARHGAP32,SMG7,PIPOX,ZNF589,CRCP,POLL,SPACA9,GRIK5,MID1,NF1,OMG,PTPA,MAPK3,PTN,PEX5,RIPOR1,CEP97,RNASEL,FOXRED2,FAM214B,KBTBD4,SLC15A2,UNC5B,PSD3,TEX15,RBFOX2,SMUG1,PLPPR2,WNK1,NT5M,KAT6A" Drug 5664_DN Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ABHD6,AMPD2,APC,APOC1,APP,CA4,B4GALT6,TAOK2,ZFYVE9,HOMER3,ARMC8,RCHY1,ARHGEF10,PDE4DIP,DZIP3,CTH,ZNF804A,TRAPPC9,DRD1,GNE,PLEKHO1,FAM49B,PRELID3A,TBR1,INPP5K,MALT1,POLL,CNTRL,HNMT,IL6R,TM6SF1,ZNF862,SLC11A2,PRODH,ZSCAN32,RIPOR1,CCDC25,FERMT1,LIMCH1,SS18,EXOC7,AP4E1,FAM155A,VAV1,LMF1,ZBTB38,PRDM2" Drug 444_UP clofibrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG2,ALAD,SYT13,CASK,ARNTL,ARRB2,ASCL1,SLC4A4,EIF4G3,ATP6V0A1,CACNA1I,CAMK2G,INA,ARHGEF2,CLCN4,CNTN1,GREB1,B3GAT3,TMCC2,DTNA,SIDT2,EPHB1,TBC1D16,FGFR1,FHL1,FLNC,RAB40B,GNAS,ICA1,JAK2,KHK,NRGN,NTRK3,PLXNB1,FSD1,ARHGEF10L,RNASEL,SH3GL3,SLC11A1,ELMO2,ZKSCAN3,SNCA,TMCC1,RGL1,EXOC7,ATP13A2,NDRG4" Drug 6814_DN Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASPHD1,AK2,CDC42BPA,ARHGDIG,MARK4,ADAM15,BMP7,TAOK2,AKAP7,CSF1R,SOCS5,MFAP3L,KBTBD11,CNNM1,EFNA3,SORBS3,NCALD,CDKL3,EZH1,ZNF589,FAM49B,INPP5K,HSF2,KCNH2,GIT1,STRN3,PRKAR1B,PRPH,GSTCD,SAFB,SLC1A7,SLC9A5,KDM4C,SPTAN1,ST5,MAPK8IP3,TTBK2,ATP11A,EXOC7,IQCE,KIAA0930,CRTC1,ZNF34,PLPPR2,WIPF2,EPM2A,PHTF2" Drug 2556_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,MRTFA,CDC42BPA,PPFIA1,ADAM23,ADAM15,CACNB2,CAST,AP4M1,FOXN3,TPP1,QKI,AKAP7,CREM,PPP1R16B,DOCK4,SMG7,ABI2,IRAK4,TUBD1,LRRC23,CINP,FAM49B,INPP5K,CACFD1,NCKAP1L,IPO5,VWA5A,MAP4,MEF2C,AFF1,CNOT4,CDK14,PIK3CD,RETREG1,MSANTD2,PPP4R3A,ARHGEF40,ELMO2,BTBD7,SPTAN1,PDLIM2,DMXL2,TCF7,THRA,TNNT1,FIP1L1" Drug 2505_UP Ricinine [524-40-3]; Up 200; 24.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "TKTL1,MTUS1,ANK1,PPFIA2,APAF1,APBA2,APBB2,ATP6V0A1,FGF17,NRP2,SYNJ1,ARHGAP33,CHRNA4,CLCN4,RAB26,MICAL2,PDE4DIP,KIAA0513,DAPK3,CNIH3,CDHR1,RRAGB,FHL1,FLT1,PDLIM5,ARPP21,ERAP1,NEU3,PCDH17,NCKAP1L,KLF12,IL6ST,KCNN1,ADAM11,PDE1C,RIPOR1,RAB3IL1,BEND5,KLHDC8A,ZSWIM8,IZUMO4,CLSTN2,MAPK8IP3,TMOD1,TNNT1,RUNDC3B,KCNAB1" Drug 384_DN retinoic acid; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACTN2,ADORA2A,SEMA6A,DOC2A,GAS7,MARK4,RASL11B,CACNA1A,KALRN,INA,CHGB,LY86,GREB1,KLHL3,DRP2,EDNRA,EGR3,ELAVL4,ELN,LRRC23,EPHB1,TBC1D16,DLL3,GAD2,HPGDS,GLYR1,ADAMTS6,IRF8,SCIN,MAOB,MBD1,RETREG1,MAPK7,RGS12,SYNDIG1,SH3GL3,ZKSCAN3,SNAP25,ZC3H13,CLASP2,SSTR2,RGL1,TNS1,TRIO,SSBP2,VAV2,ZNF184" Drug 5002_DN Cholecalciferol [67-97-0]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "BIN1,APC,APP,MARCH3,ATP6V0A1,BCL7A,ST3GAL5,KYAT1,SYNGR3,MAGI1,CLGN,ADGRG1,RCBTB2,CLU,STOML1,PDE4DIP,RIMS2,DOCK4,DNM1,GNE,DTNA,SORBS3,LRRC23,BAIAP2,GPR37,CACFD1,MAP4,MPP2,MYO9A,SLC11A2,RETREG1,FSD1,PPP2R2B,RAD52,RGS10,SHANK2,SLN,SPTAN1,ARHGEF12,CRTC1,PARD3,CABIN1,FAM155A,EMSY,MPPE1,EPM2A,SSPN" Drug 1488_UP Captopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACTN2,PLA2G6,BIN1,CDC42BPA,APAF1,APBB2,SLC4A4,CFLAR,SCAPER,GYG2,BTRC,ARHGAP33,GREB1,LYPD1,SHANK1,PHF20L1,LRRC23,SPEG,FGFR1,BAIAP2,ELOVL5,C2orf72,INPP5B,KCNH2,KCNN1,VWA5A,MDM4,ADAM22,NF1,CLDN11,PDE4D,PRKAR1B,PTHLH,RGS7,BTBD7,MAPKBP1,SNCA,EMC1,ARHGAP26,ARC,MCF2L,EXOC7,CRTC1,CADM1,KCNK12,SPHK2,PRDM2" Drug 1702_DN Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASPHD1,MRTFA,PPFIA3,SHROOM2,NUMB,ATM,GYG2,LRBA,MAGI1,LYPD1,OPTN,ZNF589,FER,FGFR3,BAIAP2,GLS,MUM1,HNMT,HSD17B1,ICA1,INPP5B,MIA2,MITF,NAP1L1,CNOT4,OGDH,PLXNB1,GON4L,RIPOR1,TMEM231,RAB3A,RPS6KA2,ZNF821,SHANK2,ZBTB43,ASTN2,ATP11A,SIN3B,TRIM2,TNS2,CRTC1,TRPC1,CADM1,VAV2,MICAL1,LMF1,EVI5" Drug 3264_UP Pepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "MRTFA,APAF1,PLA2G4C,PDE8B,MARK4,ASPH,CDK5R1,SCAPER,OSGIN2,WASF1,BAIAP3,HAP1,CBFA2T2,CDC42,ARMC8,ENTPD4,SDC3,RIMS3,RUSC2,SLC12A6,DTNA,ELAVL2,DMTN,SPEG,DISC1,GART,RND1,GPD2,INPP5B,KCNH2,MEIS2,KITLG,MYO9A,NUMA1,PIK3CD,SMIM7,PPARA,MAPK7,AP1AR,LIMCH1,CAMTA2,TACC1,ZNF34,HEY2,TPM2,EMSY,MVB12B" Drug 6869_UP STOCK1N-28457; Up 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "CNTNAP1,ALDH4A1,CFLAR,CA4,STOML1,SMARCAL1,CRY2,CSF1R,EDRF1,LYPD1,KBTBD11,EPB41L1,F3,FHL1,PDLIM5,HBS1L,GNG3,SPACA9,BTN2A1,HSD17B1,TM6SF1,MMP17,PALM,PDE4A,PLTP,PPP5C,CCDC40,C1orf54,ZDHHC14,RGS12,RNASEL,NEK11,RPS6KA2,SLC22A4,CXXC4,ZNF423,IQSEC2,TSPYL2,INKA2,MAPK8IP3,TK2,PARD3,ZKSCAN5,SYNC,PRDM2,NT5M,KCNAB1" Drug 7290_UP Proxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,MTUS1,ALK,BIN1,ATP1A3,SYNJ2,SCAPER,TAOK2,ZFYVE9,CLCN4,CREB5,PDE4DIP,ARHGEF4,SEC14L5,MFAP3L,ATN1,EGFR,ZNF391,ETV1,GAD1,ZNF276,ATXN2L,KLF12,KCNC1,KCNJ3,KCNMA1,KHK,LIG4,SCAMP5,MMP16,NCF2,NFYA,PIK3R1,RAD52,ZCWPW1,ENOX1,SCN3A,ZFP30,ARHGEF12,TNS1,RUNDC3B,MICAL1,WIPF1,XRCC4,REEP1,PRDM2,DPF3" Drug 578_UP DAPH; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "MRTFA,EP400,CNTNAP1,GAS7,ALDH4A1,CAMK2B,ENTPD4,SH2B1,CSF1,DCAF8,FAM13A,ING4,HSD17B14,RABEPK,ZNF589,USP21,GPR153,SRCAP,PCDH17,PRRC2B,NXPH3,ATXN2L,KLF12,SYNPO,VWA5A,MAN2A2,OPA1,PBX1,CAMKV,POLG,RAB3IL1,TCP11L1,PEX26,FAM214B,SMARCC2,MAPKBP1,HECW1,TNS2,AHCYL2,TK2,TP53BP2,TSC1,WIPF1,NPDC1,ZNF142,PARP6,SNX27" Drug 2500_DN Nystatine [1400-61-9]; Down 200; 4.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,MTUS1,SLC4A4,ATP2A2,MYRF,CD86,SH2B1,SIPA1L1,EDRF1,DGKG,EFNA3,LRRC23,DLC1,ZNF589,IQCG,PDLIM5,ALDH1L1,SRCAP,AHDC1,ZNF276,POLL,GPM6B,GPR19,GRM1,MID1,NCAM1,CNOT4,PFKFB2,PLCD1,POU6F1,CNNM2,PTCH1,MYH14,SLC11A1,DOK5,DDN,NSFL1C,SYN2,ADGRL3,KIAA1107,WWC1,TCF7L2,ZBTB16,MAP3K12,NUP214,ACTR3B,SENP7" Drug 6465_DN Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG3,SRPX,TRMT9B,CDC42BPA,APP,CDC14B,MARK4,ATM,KIF1A,CFLAR,CRLF1,SLIT2,ZFYVE9,ABI3BP,BAG4,SH2B1,PDE4DIP,GREB1,DCAF8,PARD6A,DSCAM,PRELID3A,INPP5K,GLS,RASSF8,MAPT,MATK,ZNF862,P2RY1,PDE3B,PMS2,TMEM104,PTN,RGS10,FBXW7,MAPK12,SYBU,SLC20A2,SOX2,ARC,IQCE,FBXW11,SLC44A1,ZMYND8,TSN,MAP3K12,AAAS" Drug 892_UP 5162773; Up 200; 7uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADD1,MRTFA,APBB2,SLC4A4,STX16,CFLAR,CAMK2B,CBFA2T2,CDC27,LRRFIP1,FAM189A2,FADS2,VAX2,SLC4A7,ARHGEF4,GIT2,DTNA,FCF1,SIDT2,RRAGB,REEP2,DPYSL4,RAB30,GNAS,GPD2,SPACA9,GRM8,HNMT,KIF2A,MDM4,MPP2,LYRM9,CNOT4,PRKAB2,ROM1,ZNF821,FNDC3A,ANKRD6,FAM214B,SHANK2,PHLDB1,ARHGEF9,MTCL1,KAT6B,XRCC4,SSPN,SENP7" Drug 6168_DN 2-propylpentanoic acid; Down 200; 1000uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ACTN2,ADD2,APAF1,APOC1,ASPH,ZSCAN18,BACH1,SCAPER,CBFA2T2,ZMYM4,PLAA,OSBPL3,ARHGAP32,KIAA0753,RHOBTB1,TSPAN5,COQ7,FOXG1,ANKFY1,PDLIM5,GALC,SRCAP,GLS,HTATSF1,GPD2,SLC11A2,NUMA1,MAPK8,SAMD9,PTK2,RAB3A,ZNF493,ST6GAL1,RAB3GAP1,DDN,ZC4H2,CEP68,DNMBP,TCF7L2,AHCYL2,KCTD2,RBFOX2,PLPPR2,VIPR2,WNK1,KCNAB1,NLRP3" Drug 7268_UP Isoxicam [34552-84-6]; Up 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,KIDINS220,ARRB2,ZBTB10,PTBP2,EPS15L1,SLC4A7,CTNND2,EIF5,TUBD1,PLEKHO1,ANKMY1,ST3GAL6,TPK1,COPS8,TDRKH,GPER1,MUM1,MAN1B1,KCNN1,KIF5C,MKLN1,AFDN,NACA,NF1,PDGFRA,PIK3R1,STRN3,MAPK7,PTPRN2,RAB3A,ATG16L1,AP1AR,SCG5,ZHX3,CAND2,SPTAN1,ZBTB43,THSD1,SS18,ELOVL4,ASTN2,KIAA1107,ARHGEF12,ZNF189,NAV3,PLSCR4" Drug 447_UP retinoic acid; Up 200; 1uM; PC3; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RBM10,AMPD3,APBB1,APOC1,APP,PRX,BRINP2,CFAP410,CALB2,CBFA2T2,NEURL1,ZFYVE9,AKAP6,IFFO1,CPS1,NCOR2,SNPH,DPP6,EFNB3,SUGP2,PRKAG2,POMT1,C1QL1,PRRC2B,GPM6B,GPR37,ATXN2L,HTR2A,CD200,NUMA1,SNTG1,PCDH9,PTPRN2,ACSM5,SLA,SLC1A3,KDM4D,ZSWIM8,LHPP,PLCB1,EXOC7,AHCYL2,CABIN1,TUB,VIPR2,VSNL1,RNF170" Drug 1158_DN chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG3,KIDINS220,ADAM23,SYNJ2,SCARB1,QKI,HOMER3,SLC4A7,BAG4,EDRF1,INTS1,SIRPA,DTNA,FRY,TUBD1,SCML2,PDLIM5,FAM49B,CACFD1,MAP4K5,AGBL5,MIA2,NF1,NUMA1,GPR85,PIK3R1,RETREG1,WBP1L,SNRK,ATG16L1,ARID4A,RNASEL,GSTCD,ATXN1,SEC14L1,KBTBD4,SLC15A2,MAPKBP1,SPTAN1,RGL1,TCF4,TCF7,ARHGEF12,AHCYL2,KCTD2,ATP6V0E2,EVI5" Drug 373_UP "estradiol, USP; Up 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "KIAA1324,GAS7,BRINP2,SLC4A4,MTMR3,BAIAP3,CA12,CACNA1A,HAP1,ZMYM4,CHD1L,MICAL2,FBXL5,FEM1B,SORBS3,ELAVL4,PIPOX,OLFM1,FGFR1,FGFR3,BAIAP2,CAMSAP1,RUNDC3A,ZNF638,ATXN2L,JAK2,KCNJ5,ADAM22,NF1,NTRK3,PLCD1,LRRN3,RET,RGS3,IL17RB,ZNF821,SYBU,SLA,TTC17,PALLD,RAP1GAP2,TROVE2,TCF7,TMPRSS5,UBE3A,AMOT,ZNF74" Drug 2709_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG2,AGT,PLA2G6,ANK1,APBB2,EPB41L5,CA8,CALB1,CDO1,CBARP,ZFYVE9,SLC24A2,CNTFR,PLCH2,PHYHIP,SPOCK2,DBT,C2CD2L,ECM2,FOXG1,GCNT2,GPM6B,SPACA9,KIF3A,KCNJ3,MBNL1,SCAMP5,MX1,MYO6,NF1,CNOT4,PGAM2,PPARA,PRKAR1B,PTPN13,GAL3ST4,CRTAC1,SYNDIG1,ST6GAL1,SNCA,SPART,ACSBG1,IQCE,CHST8,BEST1,VSNL1,SENP7" Drug 7289_DN Phenindione [83-12-5]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "BIN1,APBB2,FAM131A,EIF4G3,RAB29,WASF1,PTBP2,RCBTB2,SRSF11,RAB28,AKAP7,WHRN,NRG2,DBT,FBXL5,DLG3,SORBS3,PLEKHO1,COPS8,SLC2A6,MAP4,MKLN1,NFYA,PDE1C,PDPK1,PLCD1,MED1,RAD51D,ATG16L1,GTDC1,RPS6KA2,CLIP1,ITSN1,FAM214B,LIMCH1,TMCC1,PEG10,ARHGAP26,ZBTB43,CEP68,TTBK2,DIP2A,MGRN1,HIRA,UBTF,LMF1,XRCC4" Drug 4482_DN Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NME5,APBB1,SYNGR3,ARHGAP33,LY86,AATK,DCAF8,SMG7,PLPPR4,RABGAP1L,ING4,ETV1,HBS1L,SEPT9,POLL,TDRKH,GPR19,GPER1,GPR37,SHISAL1,IL12A,KCNJ5,MMP16,NF1,CLDN11,STRN3,POU3F2,MINDY2,PRKAR1B,CNTLN,PID1,RGS3,KIRREL1,IL17RB,SEC14L1,ASAP3,SIRT2,BTBD7,ZNF667,SNCA,MLC1,KIAA1107,AHCYL2,R3HDM1,CADM1,MICAL1,PARP6" Drug 2724_DN Amrinone [60719-84-8]; Down 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RALGAPA1,AMPD3,CDC42BPA,PPP4R4,ATP2B1,BACH1,SYNJ2,MAP7,CHM,NMT2,CREM,SIPA1L1,USP6NL,DOCK4,ARHGAP32,DTNA,ANKMY1,FER,SEMA4D,ATP2C1,INPP5K,GPR75,MSL3,PADI2,ATXN2L,ITGAM,NRGN,NUCB1,PCDH9,PENK,PTPA,PRKCZ,MAPK7,MAPK8,PTAFR,PTPRO,TMEM206,WDTC1,FAM168A,PLCB1,KIAA1107,TCF7L2,SZT2,TPM1,ZMYND8,ZNF225,ACTR3B" Drug 2408_UP Disopyramide [3737-09-5]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ARNTL,ATP2A2,KIF1A,CACNA1I,SEPT7,HOMER3,PCYT1B,FAM149A,DGKG,SPOCK3,DTNA,TNK2,ERBB2,FGFR1,PDLIM5,GFRA1,GUCY1B1,KCNJ5,MAP4,MMP16,MYCN,NEK1,PDE3B,PDE4A,PLCD1,PPARA,RGS3,RGS12,NUDT11,CLIP1,RYR1,PPM1E,PEX26,TMCC1,RBM26,RAP1GAP2,CLSTN2,SS18,ACSBG1,PDLIM2,TBL1X,CRTC1,TMOD1,TPM1,AMACR,NSD2,NLRP3" Drug 7439_UP Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "SLC12A5,LTBP4,PPFIA3,ALDH4A1,MPDZ,BCL7A,SCAPER,WHRN,FAM169A,PPP6R2,DAPK3,C2CD2L,TOM1,SIDT2,ING4,MRNIP,EPB41L1,FGFR3,TRAF3IP2,ALDH1L1,LPAR4,CACFD1,ITPKB,MAP4,NPTX1,SETD4,PALM,NLE1,PRPH,RIPOR1,KCTD17,EMID1,SBF1,EPN2,SLC11A1,BTBD7,SMARCC2,ZCCHC24,TSNAXIP1,ZHX3,ZSWIM8,NCDN,ASTN2,FAM208A,DMXL2,SLC30A3,MVB12B" Drug 6840_DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RALGAPA1,ARID1A,ADCY6,EPB41L5,CFLAR,SCAPER,CACNA1D,RAB28,HOMER3,CREM,CNTNAP2,DZIP3,CTH,GREB1,ARHGEF4,MFAP3L,EXOG,DSCAM,EDNRA,ING4,TNK2,NCALD,ZNF589,OGA,GNG4,MAPT,KITLG,GIT1,NASP,NUMA1,PDE3B,NKAIN1,RGS12,RNASEL,PAQR6,SLC9A5,SLC20A2,COA1,ZCCHC24,TROVE2,VPS13A,PLCB1,ATP11A,ARHGEF12,ZNF34,CABIN1,RBFOX2" Drug 2203_DN Karakoline [39089-30-0]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "RALGAPA1,ALK,PPP4R4,ATP2A2,ADAM15,CACNB2,CAMK2G,CAPN3,SULT4A1,AKAP7,CSF1,EDRF1,DBT,RCAN1,EEF1A2,SIDT2,EFNB3,RASGRP2,ERCC2,KIAA1109,CRCP,ICA1,IL6ST,AFF1,MOBP,SLCO1C1,PDE4D,CCSER2,STRN3,KLK6,PTK2,CEP97,RAD52,ANKRD6,SLC11A1,VAMP1,EXOC7,PCDHGA10,R3HDM1,RBFOX2,UBTF,ZFP37,LAMP5,URM1,WIPF2,KAT6A,TIGD6" Drug 2303_UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "CDC42BPA,APC,CFLAR,SYNJ1,GYG2,CACNA2D1,CALB2,HIP1R,RUNX1T1,CD86,GPR37L1,CLCN4,AKAP6,NCAN,CYBB,SGK2,EFNB3,HSD17B14,VPS13B,RASGRP2,KCNMB2,CDHR1,ZNF589,FHL1,PCLO,GRM1,PTGDR2,ICA1,KIT,MAPT,CEP41,MAPK10,PRODH,PTHLH,RAB3IL1,MYH14,S100B,NTNG1,SLC6A9,SNCA,ZCCHC24,BEX1,DAAM2,TPM2,LAMP5,PLSCR4,CAMK1G" Drug 5644_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "CDC42BPA,SEMA7A,APC,ALDH7A1,CRLF1,CACNA2D2,CNTN1,CSF1,BRINP1,DTNA,EGFR,EIF4G2,ELAVL3,ELN,C3orf18,NCALD,SCML2,DLC1,FHL1,C1orf61,GNAL,ITPKB,KCNMA1,MOBP,MYT1,KCNK10,PDE1C,ELOVL2,PTN,FAM120C,ZFHX4,TCP11L1,RASA3,NLGN1,SLC2A5,FAM214B,DOK5,SYT11,ATP11A,PCDHA5,AHCYL2,CHST8,TMOD1,TNS1,SEZ6L,VIPR2,SYNC" Drug 1771_UP Calycanthine [595-05-1]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADCY2,AP2A2,C1QTNF3,CDC42BPA,APOC1,ALDH4A1,NRP2,CLDN10,CHN2,TAOK2,SLIT2,RAB26,CTIF,EFNB3,ING4,GPHN,DLC1,C1orf61,TRMO,CAMKK2,GABRA4,GALC,PCDH17,NXPH3,HTR2A,ARHGAP12,TM6SF1,GIT1,NOS1,NUCB1,OPCML,ENPP2,GPSM2,LRP12,MAPK9,PTCH1,PTPRN2,RAB3IL1,RGS12,MYH14,FAM102A,ELMO2,DOP1A,OBSL1,SEZ6L,TPM3,HIRA" Drug 1516_UP Loxapine succinate [27833-64-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASIC1,ADD2,ADORA1,ADORA2A,AK2,AMH,AQP4,CFLAR,SYNJ2,GYG2,ARHGAP33,CACNA2D2,HOMER3,AKAP7,TENM4,EDN1,EFNB3,FOXG1,IQCG,TBR1,GABRA1,NEU3,GFER,TXNL4A,POLL,TDRKH,ATXN2L,ADAM22,PALM,CDK18,PURG,LRP12,MINDY2,MAPK7,MAPK10,PRODH,ZFHX4,SH3BP2,ITSN1,EPN2,SSTR2,STX1A,SEZ6L,TTPA,LAT2,GDPD5,NLRP3" Drug 3616_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG2,AP2A2,AMT,ARHGDIG,SGCE,CA4,ARHGAP33,FOXN3,SOCS6,STOML1,BAG4,SIPA1L1,PDE4DIP,SDC3,EDRF1,MFAP3L,EXOG,DMPK,MRNIP,FOXG1,C1orf61,GAB1,GAD1,B4GALNT1,ALDH1L1,MSL3,ITPKB,BCO1,LYRM9,PPP5C,PRKCB,MAPK8,PRPH,PTPRO,ZSCAN2,RGS10,TNIK,ZHX3,KDM4C,STX1A,SLC44A1,TMOD1,FLRT2,ZIC3,PLSCR4,EPM2A,ST7" Drug 5107_UP Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "PKP4,KCNAB2,APBB2,ADAM23,BTRC,MAGI1,ARHGAP22,SH2B1,ABCG1,SLITRK5,FAM131B,TM9SF4,CTIF,SIRPA,MFAP3L,RUSC2,DTNA,ST8SIA3,MRNIP,COQ7,PTK2B,ST3GAL6,BAIAP2,SORBS1,RUNDC3A,GNAL,SPACA9,CNOT4,NPR2,PCBP3,MINDY2,LRRN3,PTPRH,RGS10,RGS12,RPS6KA2,IL17RB,SLC4A3,KDM4C,ARHGAP26,SPTB,ZBTB43,MAPK8IP3,SYT11,TK2,TRPC1,EPM2A" Drug 3289_DN Biotin [58-85-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "AP2A2,APOC1,ASPH,NCOA1,STX16,SYNJ2,CFAP410,LRRFIP1,CLGN,PLEKHB1,COL9A2,SH2B1,CSNK1E,DCAF8,KBTBD11,CNNM1,SIDT2,EML1,TXNL4A,SLC2A6,PADI2,HNMT,IL6ST,KCNH2,MAP4,MBD1,MPP2,POLG,RIPOR1,RAB5B,SLC25A36,GSTCD,ROBO1,WLS,TRA2B,TROVE2,SS18,ASTN2,ATP11A,TACC1,IQCE,TBL1X,TCF7,ATP13A2,ZMYND8,GDPD5,HPS4" Drug 4220_UP Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASCL1,DDX3Y,ATP1A2,CCK,USP2,GPR37L1,CHRNA4,NRXN2,CABP1,NRG2,CSF1,RGS6,NOS1AP,MFAP3L,TRAPPC9,ABCC9,ST8SIA3,EPB41,ANKMY1,ST3GAL6,C1orf61,GABRA5,GJB1,GLI2,PTGDR2,HTR5A,KCNA2,KCNH1,MMP16,P2RX7,PCSK5,PTPRG,GAL3ST4,FOXRED2,RASA3,SLA,PKNOX2,MAST1,TSNAXIP1,MAPK8IP3,TRIM2,TEK,TNS1,TRO,LMF1,PRDM2,NLRP3" Drug 6329_DN Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG3,MRTFA,SLC4A4,TBRG4,BAG4,ARHGEF4,TOX,DBT,SPATA2,SMG7,ABI2,ING4,EPB41L1,EPB41L2,USP21,NCKAP1,INPP5K,MAN1B1,JAK2,MKLN1,GIT1,TAGLN3,OCRL,SLC25A23,RC3H2,CEP97,RGS10,LIMS2,SIRT2,NAXD,TNIK,BEX1,SRPK2,NXT2,MAPK8IP3,DIP2A,STX1A,SYT1,CLASP1,CHST8,CABIN1,TNS1,XRCC4,TRIM9,MPPE1,ST7,RNF146" Drug 2990_DN Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "NDRG2,PLA2G6,NCOA1,ATP2B2,CFLAR,SYNJ2,CACNB4,NRG2,VCAN,SLITRK5,ZNF337,TM9SF4,DBN1,KIAA0753,SORBS3,C3orf18,COQ7,ERBB2,CDKL3,FLT1,ZNF44,INPP5K,ADAM28,NCKAP1L,KLF12,VWA5A,MAP4,NINJ2,PMP22,PPP2R5C,PLPPR1,RALGDS,RGS10,CLIP1,FOXRED2,SH3BP2,ZCCHC24,FAM168A,CAMSAP2,KIAA1107,WWC1,TCF4,TCF7L2,TNS1,TRO,PCBP4,JPH3" Drug 6265_DN Thioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ASPHD1,ARID1A,EP400,APP,STX16,CCNT1,CBFA2T2,SCARB1,LHX2,COL9A2,ABCG1,FEZ1,GIT2,MED24,PARD6A,SIDT2,CDKL3,FGFR1,NOP56,DPYSL4,INPP5K,MSL3,GNG4,KIF5C,IPO5,MITF,NACA,NCAM2,NF1,NFYA,OPA1,PDE3B,NEK11,AMBRA1,PEX26,EPN2,MAPKBP1,EMC1,UHRF1BP1L,SS18,OBSL1,KAT6B,VGF,KLC2,ZNF24,ZBTB38,MVB12B" Drug 3022_UP Iocetamic acid [16034-77-8]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "ADCY2,FAM135A,ASCL1,ATP1A2,MYOM1,CACNA1I,KALRN,CBFA2T2,CDH2,NRG2,NCOR2,RGS6,MICAL2,KLHL3,ST8SIA3,SRPK3,EIF1,CACNG2,CORO2B,SIGLEC8,GFER,LILRA2,RAPGEF1,ATXN2L,SCIN,SMAD1,AFDN,MYCN,PDE4D,DUSP26,CCSER2,STRN3,PPP1R1A,FAM120C,ST6GAL1,LIMS2,KANSL3,PALLD,LHPP,MAPK8IP3,TIAM1,TLL2,PRMT8,KLC2,ZNF32,ZNF225,PMEPA1" Drug 890_UP 5149715; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "KIDINS220,ALCAM,CDC42BPA,APBB2,ATM,RGS9,BCL7A,CDK5R1,SCAPER,CAMK2B,NMT2,VAX2,BAG4,CREM,ANKMY1,FHL1,HNMT,INPP5B,KCNJ3,KPNA5,MITF,ZNF862,PDE3B,MINDY2,PTPN13,TMEM231,RAB3IL1,ITSN1,FRMPD1,FNDC3A,SMTN,SHANK2,SLC20A2,SLC22A4,SNCA,ZCCHC24,MYCBP2,KDM4C,SPART,ASTN2,TBL1X,CRTC1,HEY2,TRIO,RUNDC3B,UBE3A,SCG2" Drug 6575_UP Gly-His-Lys acetate salt; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.29E-03 1.00E+00 1.40E-02 1.59E-01 47 199 "MAP4K3,APP,CASK,NCOA1,MTMR2,CAMK2G,CLGN,SOCS6,LHX2,CLCN3,RNF14,FEZ1,SOCS5,APPL1,PPP6R2,TOM1,STX2,EFCAB2,OGA,ERAP1,INPP5K,GART,GLS,POLL,BTN2A1,ATXN2L,KCNJ3,MEIS2,LYRM9,NEK1,NPR2,SIDT1,RPRD1A,RAB3GAP1,SIRT2,BTBD7,MAPKBP1,KDM4C,SEMA4A,IQCE,WDR7,TMPO,VAV2,REEP1,EPM2A,FZD3,RNF146" Drug CID000055483 dopexamine Stitch 2.31E-03 1.00E+00 1.41E-02 1.60E-01 12 32 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CACNA2D1,DRD1,KAT8,FOLH1,INPP1" Drug CID005311037 KW-6002 Stitch 2.31E-03 1.00E+00 1.41E-02 1.60E-01 12 32 "ADORA1,ADORA2A,ADORA3,ADRB2,GRIA1,GRIA2,GRIA4,GRM3,GRM5,HTR2A,MAOB,PDYN" Drug CID000003583 AC1L1G95 Stitch 2.31E-03 1.00E+00 1.41E-02 1.60E-01 12 32 "ABCG2,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,STMN1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID003467590 STO-609 Stitch 2.31E-03 1.00E+00 1.41E-02 1.60E-01 12 32 "CAMK2B,CAMK2D,KRIT1,CD86,CAMKK2,HMGB1,ITGAM,MAPK3,MAPK4,PBRM1,GSTCD,SLC12A2" Drug CID000105060 indo-1 Stitch 2.31E-03 1.00E+00 1.41E-02 1.61E-01 27 99 "AGT,PHF12,DGKZ,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CACNA1D,CACNA2D1,CACNB2,CALM1,CHRM1,EDN1,EDNRA,ADGRV1,ATP2C1,GRIK1,KCNMA1,MAG,PRKCB,PRKCG,RYR1,RYR3,SLC8A3,SNAP25,TRH" Drug 4134_DN (-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "NDRG2,ADORA2A,KIDINS220,C1QTNF3,BIN1,CDC42BPA,CNTNAP1,RGS20,PDE8B,CFAP410,CDC27,CHM,ZFYVE9,CYBB,RUSC2,SGK2,EN2,ERCC2,FHL1,GAD1,DISC1,GNAS,FERMT2,GPM6B,IL6ST,KCND3,MAP4,AFF1,NEK1,NF1,KCNK10,PRKAB2,MAPK8,RNASEL,SEMA6D,SEC14L1,CCDC88A,MAPKBP1,SNCA,PALLD,IQSEC2,THSD1,EHBP1,PSD3,KAT6B,WNK1" Drug 1101_UP catechin; Up 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "APBB2,APP,ARHGAP5,ATM,MPDZ,UBE2L6,EPS15L1,CLOCK,DTNA,EIF5,TNK2,TESK2,PDLIM5,CGREF1,GLUL,AGBL5,ICA1,MBD1,MKLN1,MYO9A,NAP1L1,NCAM2,NEK1,NF1,SETD4,PDE3B,PLEC,ING3,MED1,PPP5C,PRKACB,PTK2,ZSCAN32,MORC4,ATXN1,PEX26,IFT122,MYCBP2,ERC1,LHPP,FAM168A,JMJD6,FBXW11,SMUG1,LMF1,ZBTB38" Drug 4715_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ADORA2A,STX16,MTMR3,CSF1R,CTIF,BRINP1,MFAP3L,RABGAP1L,DTNA,EFNA3,RGS17,HSD17B14,COQ7,ACSL4,ST3GAL6,ERAP1,ZNF276,GLS,MSL3,GNG4,GPD2,TJAP1,DIPK1A,NEUROD1,NF1,NUMA1,PPARA,PPP2R2B,PRPH,WDR25,ZDHHC14,TCP11L1,ZNF821,ANKRD6,SOX2,SPTAN1,TROVE2,NXT2,NCDN,ARC,TRIM2,THRA,VGF,VIPR2,LMF1,C12orf4" Drug 1119_UP yohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "BRAP,OSBPL1A,APP,ARHGAP5,BMP7,SYNJ2,UBE2L6,SLC4A7,SOCS5,CTNND2,KIAA0586,INTS1,MFAP3L,DNM1,DTNA,SEZ6L2,CELSR3,SUGP2,EFCAB2,GART,KCNJ3,MAP4,MAPT,NEK1,NF1,PC,MED1,VPS13C,GON4L,RAP1GAP,ARHGEF10L,FOXRED2,ATXN1,PEX26,EPN2,SS18,NCDN,DIP2A,FAM168A,EHBP1,TPD52,BCL2L13,TFIP11,EVI5,MPPE1,JMJD1C" Drug 5498_UP Dapsone [80-08-0]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ASIC1,NDRG2,ADCY6,ADD2,PLA2G6,APC,RASL11B,MTMR3,MTMR2,CACNB2,ARHGEF1,KCNAB3,CHN2,ZFYVE9,DAPK3,HP1BP3,SHANK1,DTNA,ELAVL3,LRRC17,EZH1,FGFR1,AFF2,INPP5K,CNTRL,KLF12,IGSF1,NRGN,NUCB1,OPRL1,PDE1C,PDE1B,CDK14,CEP41,GSTCD,ZNF821,SH3BP2,COA1,RBM26,SEMA4A,TGFBR3,MICAL1,LMF1,EVI5,GDPD5,SLC17A7" Drug 4466_UP Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "SEMA7A,APAF1,AQP4,KSR1,IL33,RUNX1T1,CSF1,PDE4DIP,SDC3,CYBB,NR1D2,ABCC9,EDN1,TENM1,ING4,AMOTL2,CAMSAP1,FLT1,GABRA2,GAP43,RND1,GLI2,STON1,CACFD1,NXPH3,VWA5A,NF1,NPPA,ODF2,PDE3B,POU6F1,GRAMD1C,SNRK,PTCH1,ZCWPW1,TCP11L1,HKDC1,SLC11A1,SLC15A2,SCN3B,SZT2,THRA,CDK20,TPM2,ZMYND8,PLSCR4" Drug 4149_DN Dibucaine [85-79-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ASIC1,NDRG2,NME5,AMPD3,PLA2G4C,SYNJ1,CDH8,FOXN3,SLC4A7,CRMP1,CRY2,DCAF4,NOS1AP,GPRASP1,DCAF8,SMG7,TMCC2,HIPK3,ING4,SCML2,PRELID3A,GAD2,SEPT9,GPER1,ATXN2L,DHX35,KCNH2,KIT,VWA5A,CDK18,MINDY2,PTHLH,FAM120C,KCNIP1,SELL,PEX26,ZBTB43,TROVE2,THSD1,PLCB1,ROBO3,EXOC7,SIN3B,SCG2,KCNAB1,KAT6A" Drug 4727_DN Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "C1QTNF3,PKP4,APC,PLA2G4C,EIF4G3,CAMK2G,CBFA2T2,MAGI1,CLCN3,JAKMIP2,DTNA,EDNRA,EFNB3,MBNL2,DMTN,DLC1,KIAA1109,FHL1,AFF2,ZMYND11,GNAS,PCLO,IL6ST,LMO2,MAP4,MAPT,KITLG,MITF,NF1,GRAMD1C,SAMD9,ELOVL2,PTK2,GSTCD,FAM214B,EMC1,KDM4C,SEMA4A,TCF7L2,PSD3,PCDHA5,TMPO,CABIN1,RUNDC3B,WNK1,PHTF2" Drug 5091_UP Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ACTN1,ADRB2,KIDINS220,PPFIA4,GAS7,APLP1,CBS,NRXN3,DNAJB5,COL9A2,ABCG1,CNTNAP2,SGSM2,SIDT2,PDLIM5,GAD1,GPM6B,ICA1,MAP4,NDUFA5,NF1,CNOT4,MINDY2,PPP5C,SNRK,PTPRH,TMEM231,RPS6KA2,SCN2A,SEC14L1,DZIP1,SLC4A3,SPTB,ZBTB43,DDN,INKA2,MAPK8IP3,PHLDB1,PDLIM2,TPM2,TRIO,ZMYND8,VAV2,LAT2,NAV3,FAM13C" Drug 2632_DN Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "BIN1,ANK3,EPB41L5,BCAS1,ALDH4A1,STX16,BCL7A,SOCS6,VAX2,QKI,ARMC8,SIPA1L1,TM9SF4,DAPK3,GIT2,FBXL5,G3BP2,FCF1,EFNA3,F3,AGAP2,FAM49B,CSPG5,POLL,GPER1,HNMT,DHX35,LIG4,MAP4,NUCB1,ELOVL2,PEX5,CEP97,ZDHHC4,ABLIM3,ZBTB43,TACC1,DNMBP,TCF7L2,TK2,CABIN1,MICAL1,XRCC4,NDRG4,MAP3K12,EMSY" Drug 5932_DN "rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ASPHD1,ADRA1D,AMPH,BIN1,GAS7,CDK10,ALDH4A1,NRP2,CLTB,PDE4DIP,PLPPR4,CHRDL1,DSCAM,TOM1,CNNM1,SUGP2,AASS,F3,SORBS1,GLRB,GNG4,SCIN,AFDN,MSR1,PAK3,PDGFRA,PFKFB2,PIK3R1,CCSER2,SH3GL2,SLA,SLC1A3,KDM4B,ARHGAP26,TROVE2,JMJD6,ASTN2,KAZN,PSD3,R3HDM1,CABIN1,TNS1,PDIA2,PLPPR2,NAV3,SLC17A7" Drug 3126_UP Gliquidone [33342-05-1]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ARID1A,NDRG2,FZD9,FAM135A,AMPH,PLA2G4C,CCDC181,ATP2B2,CACNA1D,CBFA2T2,CHGB,CHN2,EPS15L1,RAB28,ZFYVE9,PLAA,RAB26,CREB5,DRD1,F5,FLT1,SEPT9,ALDH1L1,ADAM28,GRM8,BACH2,HTR5A,ITPKA,TAGLN3,NCAM1,NUMA1,OPRL1,PENK,PFKFB2,PRPH,MRAS,ZNF365,SLC6A8,SLC11A1,SLC20A2,SNCA,FAIM2,ATP10B,OBSL1,KLC2,SLC17A6" Drug 6642_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ARID1A,NME5,PLA2G6,APC,ASPH,ALDH4A1,SYNJ2,BTRC,MAP7,PLEKHB1,IQCK,WHRN,PDE4DIP,SMG7,DLG3,PLEKHO1,EPHA5,ERCC2,TUBB4A,FGFR1,ZNF276,SYNPO,TJAP1,KIF5C,MITF,NF1,PDE1C,CCSER2,STRN3,PTPRE,PTPRH,RAB5B,MYH14,ROM1,ZNF671,CCDC88A,SLC20A2,UNC5B,MAPK8IP3,DNMBP,TMEM121,SSBP2,WIPF1,XRCC4,EMSY,UBE3B" Drug 1856_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ASIC1,CDK10,ZBTB10,OSGIN2,SPAG9,CLCN3,QKI,VCAN,PPP1R16B,PPP6R2,TBC1D5,KIAA0586,RABGAP1L,HIPK3,VPS13B,GPHN,EPS8,VPS26C,ZNF589,FYN,SEPT9,GLS,ICA1,KIF2A,MDM4,MIA2,NF1,NFYA,SETD4,ZFYVE21,CDIP1,MAPK12,ITSN1,FERMT1,PPP4R3A,ERC1,SRPK2,SEPT8,TTBK2,PJA1,TCF4,TPM1,ZMYND8,XRCC4,EPM2A,ST7" Drug 7487_UP semustine; Up 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "AGT,BCAS1,CFLAR,CACNG1,TAOK2,IFFO1,CREM,CSF1R,EDRF1,TBC1D5,HP1BP3,ATN1,FEM1B,TNK2,EZH1,FECH,KIAA1109,GABRG2,B4GALNT1,PCLO,GRB10,GRIN1,MAP4,MMP17,MN1,CD200,ADAM22,NECAB2,PPP5C,MAPK8,FAM120C,C1orf54,RGS12,SATB1,FNDC3A,SLC1A7,SLC6A8,SLC9A5,BTBD7,SLC20A2,UNC5B,VPS13A,POPDC3,TRO,TRPC1,CLIP2" Drug 4839_DN Sulfaguanidine [57-67-0]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ADRA1D,AK2,PPFIA3,ARRB1,ARRB2,MARK4,CFLAR,SCARB1,RAB28,FADS2,WHRN,PDE4DIP,ARHGAP32,DCAF8,DBT,DSCAM,FCF1,CRCP,MAP4,MIA2,NF1,NUMA1,RETREG1,PRKAR1B,PTPRE,RAB3IL1,RAD52,SAFB,SH3BP2,SMTN,SLC20A2,SLC22A4,TMCC1,SPART,TROVE2,CAMTA2,NCDN,PHLDB1,NSFL1C,MTCL1,IQCE,RUNDC3B,CLDND1,NDRG4,URM1,SMIM8" Drug 4264_DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "PLA2G6,APBB2,APOC1,PDE8B,ST3GAL5,BAIAP3,SLC16A4,LARGE1,CHN2,DNAJB5,RAB26,CRMP1,CTIF,SMG7,CHRDL1,DYRK1A,EFNA3,IRAK4,COQ7,ETV1,TAOK3,DLC1,TESK2,PRELID3A,SIGLEC8,ALDH1L1,KCNMB4,GPM6B,GPER1,DIPK1A,ITPKA,MIA2,CNOT4,RETREG1,TNPO2,RALGDS,ZFP30,FBXO11,ANKRD6,PPP4R3A,SLC22A4,KIF13A,SYT11,VAMP1,SSBP2,SPHK2" Drug 1814_DN Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ABR,ADGRF5,AMPD2,CDK10,MARK4,BID,CDK5R1,CA12,SCARB1,LHX2,CSF1,PPP6R2,KIAA0513,EFNA3,EZH1,SCML2,FGF1,FGFR1,BAIAP2,CGREF1,GAD1,SYT17,DISC1,SRCAP,USP19,SLC2A6,KIFC3,MX1,ODF2,SLC25A23,FA2H,PTPA,BCAS3,MCMBP,ATXN1,SUPT20H,FAM214B,IFT122,ROBO3,EHBP1,TRIM2,HIRA,LMF1,UPF3A,EPM2A,PHTF2" Drug 5954_UP PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "SEMA6A,ARRB1,RGS20,BAIAP3,CA4,RUNX1T1,ADGRG1,RAB28,PICK1,CNTFR,SH2B1,NCAN,CYBB,TBC1D5,RUSC2,PARD6A,DRD1,DUSP9,EGR3,STX2,ZNF589,EFCAB2,TMEM8B,POLL,GPR37,LMO2,NF1,NUMA1,PFKFB2,PIK3CD,EPN1,MAPK7,ZDHHC14,SBF1,ZNF365,SPART,ATP10B,VAMP1,WSCD1,TCF7L2,SZT2,HEY1,DAAM2,LAT2,ZNF24,KCNAB1" Drug 1211_DN retinoic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ABR,APBA2,BCL7A,WHRN,PDE4DIP,CNTNAP2,SNPH,HDAC4,B3GAT3,SEZ6L2,EFNA3,EIF5,ERCC2,FGF1,GAD1,GFER,PRRC2B,INPP5B,L1CAM,MAP4,NDP,NFIX,NPR2,SETD4,PAK3,PC,PDE4B,PTPA,BCAS3,PEX5,RIPOR1,SEC61A2,IL17RB,SH3GL2,ASAP3,ZBTB43,TROVE2,THSD1,KAZN,TBL1X,AHCYL2,TIMP4,TSC2,NPDC1,MAP3K12,WIPF2" Drug 2784_DN Retrorsine [480-54-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "APBB2,PPFIA3,ATM,SOCS6,ZFYVE9,NMT2,HOMER3,BAG4,ENTPD4,HDAC4,HIPK3,COQ7,KIAA1109,BAIAP2,GALC,IL6ST,INPP5B,KCNH2,KCNJ3,IPO5,MDM4,MITF,MYO9A,NFYA,NPR2,NPTX1,RETREG1,MBOAT7,GON4L,PTK2,RAB5B,GSTCD,ANKRD6,ZKSCAN3,COA1,WDTC1,POGZ,SS18,MCF2L,TMOD1,TMPO,PARD3,ZKSCAN5,WIPF1,MPPE1,PHTF2" Drug 4305_DN Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "AK2,SCAPER,SRSF11,CHM,DNAJB5,RAB26,HOMER3,ENTPD4,CREB5,GIT2,CNIH3,CNNM1,STX2,SPIN1,GPR37,RASSF8,AGFG1,IL6ST,KHK,MAP4,MMP16,MX1,NFIX,NUMA1,NLE1,STRN3,PRKAB2,PKN2,SAMD9,TMEM231,SEC14L1,KBTBD4,TNIK,ZBTB43,TTBK2,PLCB1,TBL1X,TCF4,PSD3,DICER1,TMPO,R3HDM1,SF1,ZNF24,WNK1,PRDM2" Drug 4021_UP Nadolol [42200-33-9]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "CDC14B,ASCL1,ADAM23,NRP2,CFLAR,CDH8,PLEKHB1,ZFYVE9,IFFO1,TCEAL2,SGSM2,ABCC9,ST8SIA3,HIPK3,CELSR3,DLC1,SIGLEC8,LYVE1,GRM1,JAK2,KCNF1,MAPT,TM6SF1,NOVA2,PIK3R1,RETREG1,PPARA,PKN2,C1orf54,BEND5,RFX2,ZNF671,RPS20,SCN3A,MRAS,TNIK,NPAS3,PHLDB1,VAMP1,MCF2L,DOCK9,CDK20,TRIO,VGF,SLC17A7,CAMK1G" Drug 4317_DN Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "NME5,ALK,MRTFA,EP400,ATM,ADGRB2,CFLAR,CFAP410,CACNA2D2,FOXN3,DNAJB5,CNTN1,CPS1,CRY2,CSNK1E,PDE4DIP,DCAF4,ING4,FGF1,CINP,OGA,GNG4,IL6ST,KIF5C,NDP,CNOT4,NUMA1,ODF2,PDE4D,NLE1,RAB3A,RAB3IL1,C1orf54,ASAP3,PREX2,BEX1,ZBTB43,ELOVL4,R3HDM1,TPM2,ZMYND8,VIPR2,NPDC1,PARP6,KCNAB1,MPPE1" Drug 2527_UP Althiazide [5588-16-9]; Up 200; 10.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "RASL11B,CACNA1G,CALB2,MTMR7,STOML1,DNAJB5,FAM149A,TCEAL2,ARHGEF10,DZIP3,PHYHIP,MFAP3L,PLPPR4,EFNB3,AASS,DMTN,FGFR3,FLNC,TOX3,GNG4,GRM8,KCNB1,KCNC1,KCND3,KIF5C,MMP17,ADAM22,TAGLN3,LYRM9,CAMKV,PROX1,LRRC49,KLHDC8A,SLC1A3,PREX2,KANSL3,SLC11A1,TMCC1,ACSBG1,TRIM2,CRTC1,TEX15,TF,SEZ6L,CHST5,LMF1" Drug 3783_UP Ethisterone [434-03-7]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ALK,PKP4,APAF1,BCAS1,CDC14B,KALRN,SYNGR3,ARHGAP33,LARGE1,RIMS2,SV2B,SPOCK3,SRPK3,RASL12,KAT8,OLFM1,AGAP2,ZNF44,HBS1L,GNG3,GPD2,SPACA9,GRIK5,GRIN1,SOX21,KPNA5,MOBP,NF1,NPPA,NUMA1,PDE4B,KCTD17,PKNOX2,SLC6A11,SLC11A1,KDM4C,TROVE2,MAPK8IP3,VAMP1,SZT2,CRTC1,R3HDM1,TUBB1,ZFP37,EMSY,EVI5" Drug 7537_DN CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "RALGAPA1,NME5,APBB2,APC,EPB41L5,APP,LGR5,RGS20,CDK13,MARK4,ASPH,SYNJ2,CNOT8,CLCN4,PDE4DIP,GIT2,DNAJC6,CDON,YAF2,EGFR,FGF1,FLT1,GLYR1,GPD2,GPM6B,BACH2,MBNL1,TAGLN3,MYO6,NF1,NUMA1,CNTLN,PTX3,TMEM231,SAFB,ZFP30,SLC9A5,ZNF667,EMC1,THSD1,ASTN2,SEMA4A,RBFOX2,WNT7A,ZNF74,SEMA3B" Drug 955_UP 5248896; Up 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "SLC12A5,LTBP4,BIN1,APBB2,APC,APOC1,ST3GAL5,SCAPER,CACNA1D,SCARB1,ZFYVE9,CTH,PPP6R2,RIMS3,DBT,SORBS3,FGFR1,BAIAP2,FHL1,TPK1,INPP5K,SRCAP,GLS,GPD2,NR3C1,MBD1,NF1,GON4L,RNASEL,GSTCD,EMID1,RXRA,ATXN1,ZNF365,FAM214B,BTBD7,SLC22A4,MAPKBP1,SNCA,EXOC7,SZT2,TRPC1,ZIC3,REEP1,MAP3K12,PRDM2" Drug 971_DN oxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "APP,MPDZ,BMP7,SYNJ2,CA12,CCNT1,ARMC8,DCAF8,HDAC4,PARD6A,ABCC5,EFNA3,EGR3,EPB41L1,RRAGB,EFCAB2,INPP5K,SRCAP,CNTRL,IL6ST,KCNJ3,MAP4,MEIS1,SCAMP5,MPP2,CNOT4,NRGN,PIK3R1,KCTD15,SMOX,PMP22,MED1,ELOVL2,RET,ARHGEF10L,FERMT1,ABLIM3,PEX26,PPP4R3A,DIP2A,COBL,ANKRD12,KAT6B,LMF1,ZNF74,ZNF142" Drug 6876_DN BAS 012416453; Down 200; 38uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ADD1,ADD2,BIN1,CDK10,ARHGAP5,PTBP2,KRIT1,NMT2,NIPBL,HOMER3,ENTPD4,SOCS5,DZIP3,ZFYVE16,DBT,MED24,RABGAP1L,TMCC2,SEC16A,ABCC5,EN2,DENND4A,GAD1,NCKAP1,GPER1,IFI16,KHK,SETD4,MINDY2,KIRREL1,CLIP1,HSPA4L,PDZD2,POGZ,NCDN,VPS13A,ANKRD12,SEMA4A,WWC1,WSCD1,ARHGEF12,FAM155A,ZBTB14,SYNC,EVI5,HPS4" Drug 7534_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ARID1A,FAM135A,AMPD3,CACNA1D,BRSK2,B4GALT6,LHX2,BAG4,SIPA1L1,GREB1,CTIF,DCT,TRAPPC9,RASGRP1,SUGP2,EGR3,DLC1,ZNF589,FGF12,FLNC,GPR153,TMEM8B,SEPT9,LYVE1,GLS,NXPH3,JAK2,MDM4,MITF,NFYA,PCDHGC3,PCDH9,SMOX,MINDY2,GDPD2,PTAFR,ZDHHC14,RET,TCP11L1,SGK1,CCDC88A,THSD1,ST5,THRA,TRO,VGF" Drug 1699_DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "BRAP,MTUS1,MRTFA,CDC42BPA,DGKD,PDXK,ARRB1,CDK13,ATM,STX16,CFLAR,QKI,SOCS5,DCAF8,INTS1,GIT2,DNM1,SIDT2,EFNA3,SH3GLB1,SUGP2,PLEKHO1,VPS26C,KAT8,AHDC1,IL6ST,KCNF1,MITF,OGG1,PDE3B,GON4L,PTPRE,FBXW7,EPN2,ZNF430,ZSWIM8,TACC1,EXOC7,KIAA0930,TNS2,AHCYL2,ATP13A2,PARD3,ZMYND8,HIRA,MPPE1" Drug 2213_DN Ivermectin [70288-86-7]; Down 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "NDRG2,KIDINS220,SEMA4G,CDK13,MARK4,SYNJ2,GYG2,CAMK2G,MAGI1,TAOK2,SLIT2,LHX2,DBN1,DMTN,ZNF589,FGFR3,TMEM164,MALT1,RAB30,GPER1,GPR37,BRINP3,ITPKB,KCNH2,LMO2,MAP4,PCDH9,CDK18,PMP22,NKAIN1,ATG16L1,RET,NEK11,LGR4,ATXN7,ANKRD6,EPN2,SLC6A8,SCMH1,ZCCHC24,CEP68,SLC44A1,TIAM1,ZIC3,REEP1,EMSY" Drug 1185_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "BRAP,MTUS1,APC,ADAM23,CAMK2G,TPP1,ARHGAP32,DBN1,SPATA2,C2CD2L,RBM12,ENO2,COQ7,ZNF589,CAP2,POMT1,GART,LILRA2,ITGA7,ITPKB,NUMA1,PDE4D,PRKCZ,TMEM104,RAB3IL1,RET,RGS10,RNASEL,CCDC25,ATXN7,SEC14L1,GALNT10,PPP4R3A,BTBD3,MAPKBP1,SNCA,ZNF302,VPS13A,IQCE,KIAA0930,TCF7L2,ZMAT3,CABIN1,RBFOX2,MAP3K12,ST7" Drug 2844_UP Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "FZD9,BIN1,SEMA4G,ATM,N4BP2L1,ADAM23,CFLAR,PROM1,CACNA1I,CA4,NEURL1,RCBTB2,TPP1,NOS1AP,SGK2,SIDT2,EFNB3,C3orf18,VPS13B,NCALD,FGF12,FAM49B,GAB1,DISC1,SEPT9,KHK,MID1,AFF1,ADAM22,PCDH9,PIK3CD,NECAB2,MAPK10,RGS12,RASA3,PEX26,SLC9A5,SNCA,KDM4B,IQSEC2,POPDC3,ZEB1,CRB1,ZKSCAN5,REEP1,PRDM2" Drug 2504_DN Skimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.33E-03 1.00E+00 1.42E-02 1.62E-01 46 194 "ASIC1,APC,ARHGEF7,CAMK2G,ARMC8,CPS1,DCTN1,RHOBTB1,DTNA,IRAK4,TNK2,DENND4A,PCYOX1,SEPT9,ARFIP1,PRRC2B,LILRB4,ACOT7,ITGA7,PAXBP1,NFYA,SLC11A2,PDE4B,RETREG1,DEF8,ZSCAN32,GTDC1,GSTCD,SPATA7,KDM4C,KIF1B,TAB2,DIP2A,GSE1,NSFL1C,KAZN,EXOC7,ZEB1,TK2,LAT2,ZNF32,PRDM2,EVI5,CIAPIN1,EPM2A,NLRP3" Drug ctd:D020001 1-Butanol CTD 2.35E-03 1.00E+00 1.43E-02 1.63E-01 21 71 "AGT,APP,C5,CHRNA4,CHRNB2,EGFR,PTK2B,RACK1,FGR,GABRA1,GABRG2,GAP43,GRM1,GRM5,IGFBP1,P2RY1,PENK,PRKCB,PRKCZ,MAPK3,SYN1" Drug CID002724274 tungsten carbide Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "SLC4A4,ARHGAP32,DMTF1,CLASRP,MBNL1,MT3,NOVA2,PDLIM2" Drug CID000010624 psilocybin Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "DMTN,GRM2,HTR2A,HTR5A,MATK,SOX10,SPP1,SMUG1" Drug CID000422254 NSC142627 Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "ALDH7A1,DLG4,LOXL3,MAOB,PCSK2,ADHFE1,ABCC8,HHIP" Drug CID000107950 "CL 218,872" Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "BCS1L,ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000170209 Revalor Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "BRAP,ADRB2,ALDH7A1,MSTN,IGF1,STX1A,TAC1,ZNF384" Drug CID000006321 unithiol Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "ALAD,SLC22A6,DTNB,HEYL,OGG1,TAC1,TAC3,SLC13A3" Drug CID000006782 DiBP Stitch 2.36E-03 1.00E+00 1.44E-02 1.63E-01 8 17 "DMPK,DYRK1A,POLK,GPR162,CLDN11,PPARA,SOX10,TP53BP2" Drug 4271_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.37E-03 1.00E+00 1.44E-02 1.64E-01 45 189 "KIDINS220,ALAD,PPFIA1,PKP4,ASPH,STX16,ADAM15,CDC27,CLCN3,KIAA1549L,ARHGAP24,DBT,SMG7,FCF1,FYN,CRCP,SPIN1,MAP4K5,HAS2,AGFG1,IFI16,IL6ST,JAK2,KCNMA1,MAP4,MMP16,NFIX,NUMA1,STRN3,RGS10,GSTCD,KIRREL1,CCDC88A,SS18,TBL1X,EHBP1,TCF4,ZEB1,PSD3,DICER1,TMPO,SF1,WNK1,EMSY,FXR1" Drug 4304_DN Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.37E-03 1.00E+00 1.44E-02 1.64E-01 45 189 "RALGAPA1,CDC42BPA,ASPH,ATM,CFLAR,SPAG9,SRSF11,HOMER3,FCF1,STX2,VPS26C,HBS1L,CRCP,SPIN1,HTATSF1,FERMT2,RASSF8,AGFG1,SCIN,IL6ST,MAP4,MMP16,MYO6,NFIX,PDE4D,STRN3,PKN2,SLC25A36,SEC14L1,PPP1R9A,FBXO11,ZNF667,TNIK,TBL1X,EHBP1,TCF4,ZEB1,DICER1,TMPO,R3HDM1,SF1,WNK1,PRDM2,EVI5,KAT6A" Drug CID000003844 KT5720 Stitch 2.37E-03 1.00E+00 1.44E-02 1.64E-01 45 189 "ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,PRX,ALDH7A1,KRIT1,LRBA,AKAP5,MAML1,DRD1,CALCRL,CRCP,DBF4,RAPGEF4,GRIA1,GUCY1A2,GUCY1B1,PTGDR2,MYLK2,IGF1,KCNH2,KCNJ4,NPR2,NTRK3,CNTN3,PDCD2,PDE3A,PDE4B,PDE4D,ABCB1,PLIN1,PTPA,PRKACB,PRKCB,PRKCG,MAPK3,MAPK12,SLC11A1,SLC20A2,MLC1,HHIP,VIPR2,RGMA" Drug 6831_DN Securinine [5610-40-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.37E-03 1.00E+00 1.44E-02 1.64E-01 45 189 "AP2A2,AK2,ATM,CFLAR,ST3GAL5,PLEKHB1,LHX2,RAB26,GREB1,DSCAM,EDNRA,CNNM1,EFNA3,STX2,NCALD,EXTL2,ARMCX1,ZNF589,POLR1B,FGFR1,SEMA4D,ZNF44,DISC1,INPP5K,GPR19,BRINP3,KCNJ3,MEIS1,NUMA1,OGG1,PLEC,SIDT1,RGS10,CCDC25,TTBK2,DIP2A,PHLDB1,VAMP1,PLCB1,ASTN2,TACC1,TMEM121,ZMYND8,VAV2,MVB12B" Drug CID000008230 Argipressin Stitch 2.38E-03 1.00E+00 1.45E-02 1.64E-01 19 62 "ADCY2,ADCY5,ADCY6,ADCY8,AGT,HDAC4,MYEF2,EDN1,EDN3,EDNRA,NPPA,OPA1,OXTR,PDYN,SST,AZIN2,TPM3,TRPC1,SLC17A7" Drug CID000005604 NSC56408 Stitch 2.38E-03 1.00E+00 1.45E-02 1.64E-01 19 62 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,ADORA3,CAMK2B,LRBA,SLC29A4,FDFT1,AHCYL1,CIT,DDX19B,PRKACB,TMEM132D,SYNE1,AHCYL2,TUB,UBTF" Drug CID000006560 isobutanol Stitch 2.38E-03 1.00E+00 1.45E-02 1.64E-01 19 62 "CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,LRBA,CLTA,RBM39,CS,KCNMB2,GALC,GALR1,ANLN,PTAFR,PEX5,RNASE1,FAIM2,CLSTN2,ADHFE1" Drug CID000121907 EGTA-AM Stitch 2.38E-03 1.00E+00 1.45E-02 1.64E-01 19 62 "PLA2G6,ATP2B1,ATP2B2,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB2,CALM1,CANX,RHBDL1,SV2B,SV2A,GRIK1,GSN,KCNH2,OXTR,APTX,XPO1" Drug CID000001922 8-phenyltheophylline Stitch 2.38E-03 1.00E+00 1.45E-02 1.64E-01 19 62 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,APC,ALDH7A1,P2RX6,GPR162,LPAR4,P2RY13,P2RX7,P2RY1,RNH1,P2RY12" Drug 5957_UP valinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-03 1.00E+00 1.46E-02 1.66E-01 44 184 "KIDINS220,SPARCL1,MRTFA,BEGAIN,TRMT9B,BAIAP3,CA4,CBFA2T2,ARHGEF2,CLGN,QKI,SH2B1,CTIF,RUSC2,DRD1,DTNA,EGFR,SORBS3,RCAN2,FGFR3,AMOTL2,FYN,INPP5K,ALDH1L1,POLL,GRB10,HTR5A,MAP2,NUMA1,MAPK7,TMEM231,RAB3IL1,C1orf54,PPM1E,KIF21B,RBM26,INKA2,WSCD1,SYNE1,PSD3,AP4E1,VLDLR,NAV2,SSPN" Drug 5027_UP Etoposide [33419-42-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-03 1.00E+00 1.46E-02 1.66E-01 44 184 "SLC12A5,LTBP4,ANK1,APC,RGS20,N4BP2L1,CFLAR,ST3GAL5,SCAPER,CFAP410,TPP1,DNAJB5,CRY2,HIPK3,ELN,HSD17B14,VPS13B,KAT8,SRCAP,SESN1,RND1,GLYR1,POLL,GPER1,GRIK5,ATXN2L,ICA1,ITIH2,KCNMA1,MAP2,PTAFR,RALGDS,RFX5,FAM214B,VAMP1,ASTN2,EXOC7,KIAA1107,ZMAT3,BEX4,CDK20,ZFP37,MAP3K12,SEMA3B" Drug 2758_UP Ellipticine [519-23-3]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.41E-03 1.00E+00 1.46E-02 1.66E-01 44 184 "NDRG2,APC,APOC1,CDC14B,N4BP2L1,LDLRAD4,SLC16A4,CDO1,SLIT2,RAB33A,CNR1,CRMP1,SPOCK2,DMPK,SHANK1,DUSP9,EN2,KHDRBS3,GAD1,GLS,GNG3,NR3C1,HPSE2,IL6ST,MAN2A2,MAOB,MAP4,MID1,NPTX1,NTRK2,PCDH9,PFKFB2,SERPINE2,PPP5C,ELOVL2,FAM184A,DZIP1,RPH3A,MYH15,ZCCHC24,ARC,TF,SYNC,KCNAB1" Drug 839_UP 5224221; Up 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.44E-03 1.00E+00 1.48E-02 1.69E-01 43 179 "GAS7,PPFIA3,RGS20,CARS,ARHGEF2,CLGN,FAM189A2,QKI,CREM,CTH,EDRF1,DAPK3,GIT2,DNAJC6,MFAP3L,DTNA,TOM1,MBNL2,BAIAP2,AMOTL2,GRB10,NR3C1,BTN2A1,INPP5B,KIF5C,MDM4,NRCAM,OXTR,CDK18,MAPK8,PRPH,C1orf54,SUSD4,ZNF821,ZFP30,PPM1E,ERC1,POPDC3,ZNF34,TRIO,BCL2L13,VLDLR,ST7" Drug 3993_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 2.48E-03 1.00E+00 1.50E-02 1.71E-01 42 174 "ARID1A,BCAR3,APP,BCL7A,CFLAR,AP4M1,RCBTB2,SOCS6,HOMER3,SMARCAL1,KBTBD11,COQ7,TRAF3IP2,GBX2,GPER1,DIDO1,HAS2,DHX35,SMAD1,NDP,PDE1C,PTHLH,SCAF8,ZFP30,URGCP,KDM4D,KBTBD4,CDK5RAP2,CAND2,ZC3H4,ARHGEF9,NSD1,TMPO,KAT6B,ZMYND8,UBTF,NSD2,ZNF32,PRDM10,CIAPIN1,MVB12B,EPM2A" Drug ctd:C049325 "1,2-dithiol-3-thione" CTD 2.48E-03 1.00E+00 1.51E-02 1.71E-01 162 838 "ACLY,ADRA1B,ALCAM,APBB1,GAS7,APP,AQP6,CASK,ATP1B3,ATP2A2,NAE1,C1QC,IL33,CACNA1D,CALB1,CALM1,KALRN,CAMK2D,CANX,CAST,KYAT1,CCK,RGN,CD86,CD38,COPB2,CHN2,LHX2,RAB28,PLAA,MYL6B,LY86,CNN3,CP,CDC42BPB,RBM39,AKAP12,GDA,CTH,MYADM,MATR3,TOMM20,DAPK3,YTHDC1,DDX46,GRIN3A,NR1D2,DNM2,DMTF1,GNE,FIS1,EDN1,EDN3,EDNRB,EGFR,EIF4G2,ERBB2,FABP7,ACSL4,TUBB3,RACK1,FCGRT,FDFT1,FLNC,ANKFY1,ATP2C1,ALDH1L1,GFRA2,GHR,LYVE1,GLUL,GNAO1,GPD1,RAPGEF4,ATE1,GSTT2,HMGB1,GABARAPL2,HMGCR,HNRNPK,HSP90AA1,HTR2A,ATCAY,IGF1,IGFBP1,IL6R,JAK2,LAMP2,LIFR,LSS,MAG,MARK3,MAT2A,SHC3,PTOV1,TAGLN3,MXI1,NAP1L1,NFIA,NFE2L2,NPPA,SLC11A2,PAX6,PC,PCMT1,PDE2A,PDE3B,PDE4A,PDE4B,PGAM2,PIK3R1,MBOAT7,PPM1B,PPP3CA,PRKACB,PRKCB,PRKCG,PSMA6,PTK2,PEX2,RAB5B,OXR1,RNASE1,PCMTD2,LGR4,SCN2B,SCP2,SFPQ,TRA2B,SH3GL3,ST6GAL1,SEC31A,SLC2A5,SLC8A1,SLIT1,KIF13A,KDM3A,SPTAN1,SSTR1,SS18,PHLDB1,GSE1,PLCB1,MMS19,MLST8,AGTPBP1,DOCK9,TF,TJP1,PARD3,TNS1,TPM1,TPM3,RFTN2,TTC3,TTPA,ZFP37,MAP3K12,CSDE1,STMN4,TUBA1A,DOCK8" Drug CID000017699 propinox Stitch 2.50E-03 1.00E+00 1.52E-02 1.73E-01 16 49 "ACLY,BRAP,BBOX1,CAPN3,TIGD7,CSNK1E,DCTN1,DMD,FKTN,AGAP2,ITGA7,PPP3CA,RNH1,ACSBG1,SSPN,NETO1" Drug CID000003333 felodipine Stitch 2.50E-03 1.00E+00 1.52E-02 1.73E-01 41 169 "AGT,LGR5,PDE8B,ALDH7A1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CH25H,CACNA2D2,CALN1,CACNG7,CACNG3,CACNG2,FER,CYP46A1,MYLK2,AFF1,NPPA,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,ABCB1,PKD1,RYR1,RYR3,ADHFE1,TPCN2" Drug ctd:D005947 Glucose CTD 2.53E-03 1.00E+00 1.54E-02 1.75E-01 263 1428 "ACHE,ACLY,NDRG2,ADRB2,MTA3,AGT,WDR35,ALAD,SPARCL1,OGT,LRCH2,CNIH2,APBB2,APC,DGKD,APP,AQP4,PDXK,PLA2G4C,ZBTB10,ATP1A1,SLC2A11,KIF1A,AZGP1,SEC11C,SYNJ1,FUBP1,AP1M1,SGCE,BTRC,CACNA1D,CALM1,PTBP2,CANX,SLC25A14,HIP1R,CBS,AIFM1,ARHGEF1,CDC42,CCPG1,FOXN3,CNOT8,CLTA,QKI,NIPBL,CNR1,SLC25A27,SLC4A7,ACBD5,ZNF521,NECTIN3,CRMP1,RNF14,NCOR1,TENM4,OSBPL3,ATRNL1,CALY,ST18,CYBB,GAPVD1,MAML1,DBI,DBN1,B3GAT3,MED24,DDX46,NR1D2,DMTF1,CASP8AP2,DNM1L,E2F5,EDN1,EDN3,ATL1,SGK2,EIF4G1,EIF5,ING4,CERCAM,EMX2,ENO2,LRRC17,RABEPK,ERBB2,EXTL2,REEP2,RACK1,KAT8,MED12L,MAD2L2,CAMSAP1,ATP5PD,MEX3B,FOXO3,SLC37A3,NELFCD,NBEA,SORBS1,USP16,STAG2,GAD1,AHCYL1,IQGAP2,MTHFD2,GCK,ARFIP1,PPARGC1A,TXNL4A,DBF4,GLS,GLUL,KDM2B,FERMT2,GPD2,STON1,GRIA2,NR3C1,ATE1,GSN,KIF3A,LINGO1,SLC2A6,GYG1,HBA1,MIER3,ACOT7,HMGB1,HNRNPK,HP,HSP90AA1,IFI16,IGF1,IL6R,IL6ST,JAK2,KCND2,KCNH2,KLHL23,KCNMA1,LAMP2,MAP4,MOV10,CCDC80,NASP,NCF2,NFE2L2,NKX2-2,NOS1,NPY,NPPA,SLC11A2,NUCB2,OLR1,OPA1,P2RX7,PAK3,PAX6,PC,PRTG,PDGFRA,ABCB1,SERPINE2,PIK3R1,PKM,PLCB2,SMOX,PPARA,PRKCB,PRKCZ,MAPK3,MAPK8,MAPK9,BCAS3,PTCH1,PTK2,PTN,PYGM,OXR1,RET,GTDC1,RGS12,PBRM1,RNASEL,RPL38,RPS20,HUNK,CLIP1,RXRA,SARS,GALNT10,SFPQ,ASRGL1,MRAS,COPZ1,RASA3,SCAF8,SGK1,SH3BGR,SH3BP2,CHD9,SLC1A3,SLC2A5,EPN2,LIMS2,SEPHS1,SLC8A1,CDK5RAP3,SLC12A2,SLC12A4,SLC15A2,GKAP1,SNAP25,MBD5,TMCC1,KDM4B,DOP1A,SPP1,DBNDD2,SPART,CLASP2,ADHFE1,NSFL1C,VPS13A,PLCB1,SYP,SYPL1,SYT1,ATP11A,MGRN1,EHBP1,DMXL2,WDR7,ARHGAP9,SIRT1,SLC44A1,TJP1,ACTR6,TLR4,ZFP91,KAT6B,TP53BP1,NPL,TPM3,TSC1,TUBB2A,AMOT,UCHL1,FLRT2,TOM1L2,WIPF1,CLDND1,FMN2,NDRG4,INTS3,SLC30A3,TUBA1A,NLRP3,NHSL1,ZDHHC20,AAAS,ST8SIA2" Drug CID000004794 glufosinate Stitch 2.53E-03 1.00E+00 1.54E-02 1.75E-01 22 76 "ADD3,APBB1,CACNA1A,CACNA1B,CACNA1E,COPB2,CS,CEP170,DPP6,PDLIM5,TRAF3IP2,GLUL,GPD2,GRM8,HPSE2,AGFG1,KCNH2,SEPT4,PRIMA1,RYR1,UBC,SF1" Drug CID000027525 Cloralosa Stitch 2.53E-03 1.00E+00 1.54E-02 1.75E-01 22 76 "BRAP,ADRA1D,ADRA1B,ADRB2,AGT,CBR1,CCK,NR1D2,VPS26C,GAD1,GRIK1,SCRT2,BCO1,NPY,NPPA,OPRL1,PENK,RIT2,CLIP1,ZNF365,SST,JMJD6" Drug 6665_DN Famotidine [76824-35-6]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "TRMT9B,CNTNAP1,SHROOM2,BTRC,MAP7,SYNGR3,B4GALT6,TAOK2,ZFYVE9,HAPLN1,VCAN,PDE4DIP,ARHGEF4,KIAA0513,RIMS3,KIAA0753,SMG7,TOM1,ABCC5,COQ7,DLL3,DENND2A,GAD1,B4GALNT1,LIG4,MAPT,MPP2,PLXNB1,TNPO2,PRKAR1B,GRAMD1C,PTCH1,PTPRE,MYH14,GSTCD,RPS6KA2,RXRA,AMBRA1,SMTN,TMCC1,UNC5B,IQSEC2,KIAA1107,NSD1,ARHGEF12,CABIN1,FZD3" Drug 1920_DN Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ARID1A,ADD3,APBA2,ATM,EIF4G3,N4BP2L1,ZMYM4,SRSF11,FOXN3,NIPBL,SLC4A7,ZNF337,SPATA2,SIDT2,KCTD3,SORBS3,VPS13B,FCGRT,ZNF589,FGFR1,PDLIM5,CRCP,GRIK5,CACFD1,RNFT2,NTRK3,CCSER2,KCTD15,MED1,PTPA,TMEM104,C1orf109,RFX5,RGS3,SLC11A1,ELMO2,RCOR3,UNC5B,ZC4H2,TAC3,EXOC7,TCF4,TMPO,KCTD2,TSN,UBTF,MPPE1" Drug 3935_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ADD2,ADORA3,C1QTNF1,TRMT9B,GAS7,PRX,CACNA1I,SEPT7,LY86,CNR1,DTNB,ELN,ERCC2,ANKMY1,REEP2,CAMKK2,CSDC2,RND1,GRM8,KLF12,IL11RA,ITGA7,VWA5A,PCBP3,NUMA1,PDE4B,ENPP2,CDK14,MTRF1L,NECAB2,SAMD9,PTPRB,PTX3,MYH14,RYR1,SH3BP2,ZNF334,MYH15,FAIM2,BEX1,CDK19,ATP10B,CRTC1,PCDHA2,RIMBP2,UGT8,BEST1" Drug 6947_DN clozapine; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "CDC14B,NCOA1,BMP7,CA12,SPAG9,AP4M1,HOMER3,SMARCAL1,CHD1L,CRY2,PPP6R2,DAPK3,SIDT2,IP6K2,EFCAB2,ATP2C1,GPR153,SRCAP,ZNF276,POLL,CNTRL,GRB10,MAP4,MEIS2,NCAM2,NF1,OCRL,TNPO2,RAB3A,GTDC1,LGR4,SLC15A2,EMC1,CEP68,ARC,MTCL1,SEMA4A,MCF2L,TCF7L2,ARHGEF12,PARD3,CABIN1,TRPC1,VGF,LMF1,HPS4,IFT88" Drug 4215_UP Zalcitabine [7481-89-2]; Up 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ABAT,PPP4R4,BMPR1B,BRSK2,USP2,CRLF1,CBARP,CHN2,COL9A3,NRG2,CX3CR1,FRMPD4,TRAPPC9,USH1C,EDN3,HEYL,SRPK3,EPHB1,ANKMY1,AFF2,GABRA5,ADAM28,GGT5,LILRA2,HAPLN2,HNMT,KCNC1,KCNJ5,AFDN,MYH6,DDR2,P2RX7,SEPT4,PPP1R1A,CCDC40,FOXRED2,CXXC4,SNAP25,KIF21B,NFASC,MAPK8IP3,PCDHGB6,SYNE1,DOCK9,PHF24,TEK,PRMT8" Drug 6450_UP Flucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ADRB2,SLC4A4,N4BP2L1,SYNJ2,SCAPER,BTRC,CALB1,FOXN3,CNN3,AKAP6,WHRN,ATRNL1,SDC3,CTNND2,RUSC2,SGK2,LRRC23,FGF13,ANKFY1,FYN,ZNF44,CYP46A1,GRM7,GUCY1A2,ATXN2L,CD200,CNOT4,NTRK2,OPCML,SLC25A23,MTRF1L,LRP12,PRKAR1B,ELOVL2,RAB3IL1,PAQR6,SEMA6D,PPP1R9A,FRMPD1,PPP4R3A,ZCCHC24,ZHX3,LMO3,ATP10B,NXT2,TEX15,EPM2A" Drug CID000000247 betaine Stitch 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ABR,AMT,ARHGDIG,DST,SPAG9,CBS,CDO1,SLC22A6,SLC32A1,APPL1,CTH,CDON,ELN,PIPOX,F5,FOLR2,DNER,ALDH1L1,GPR162,IGF1,MAT2A,MATK,MTTP,MTR,NCAM1,PDE2A,SLC25A23,PRODH,PSD,RNASE1,RPL15,RXRG,HSPA4L,SHMT2,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,ADHFE1,SGK3,PDIA2,WNK1,SLC38A1,SLC17A7,SLC17A6" Drug 3927_UP Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "SEMA7A,AQP4,AQP6,MARK4,ATP2B2,CADM3,RGS11,CACNA1I,KALRN,CAMK2B,CRHBP,HDAC9,RIMS3,SPOCK2,TRAPPC9,ELAVL3,ELN,RCAN2,FGFR1,HPCAL4,NSG1,STMN2,GUCY1A1,PTGDR2,SYNPO,ICA1,OMG,OPRL1,KCNK10,PLCB2,TRHDE,PPP2R2B,RFX3,TMEM206,KCNIP1,SH3BP2,SLC1A3,SLC2A5,ARHGEF40,TNIK,NMNAT2,JMJD6,VAMP1,TRIM2,MICAL1,SEMA3B,KCNAB1" Drug 2990_UP Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "SLC12A5,MTUS1,ALK,SEMA4G,ASCL1,CCDC181,AZGP1,BMP7,ENTPD2,KCNAB3,PICK1,SLC4A8,DCC,MFAP3L,SPOCK3,HIPK3,EFNB3,APC2,DLC1,GRIA1,SOX21,HNMT,IGF1,IL6ST,KCNQ3,KHK,PACRG,SCAMP5,MYH7,NELL2,OPCML,PLCD1,SYTL2,PTHLH,BEND5,SEC61A2,ROM1,KIF16B,LIMS2,CDK19,LHPP,SSTR2,TACR1,ATP13A2,TPM2,TPM3,SLC17A7" Drug 3130_UP Halofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "SLC12A5,MTUS1,BMP7,SYNJ1,FUBP1,BTRC,CACNB2,CBR1,KRIT1,COL9A3,TM9SF4,PARD6A,EFNA3,RRAGB,TESK2,HPCAL4,GAP43,ALDH1L1,SRCAP,ADAM28,PCDH17,ZNF276,HPGDS,PRUNE2,GRIK5,ITPKA,PIK3CD,PLXNB1,WDR25,PTPRN2,PBRM1,NEK11,TCP11L1,MAP6D1,FOXRED2,NTNG1,ZNF667,ZSWIM8,IZUMO4,ASTN2,MCF2L,WWC1,ARHGEF12,CRTC1,FLRT2,MAP3K12,EMSY" Drug 6127_DN Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "KIDINS220,AGT,APAF1,ZSCAN18,MTMR2,CAPN3,REPS2,CHM,ARHGEF10,PPP1R16B,KIAA0513,DBT,DCT,SPOCK3,NCALD,KIAA1109,SEPT9,WASF3,LILRA2,GRIK5,ICA1,IL6ST,ITIH2,KHK,VWA5A,GIT1,LYRM9,OMG,PLP1,PPP5C,PTPN13,TCP11L1,FOXRED2,ZNF821,PPM1E,BCAN,SLC11A1,BTBD7,IQSEC2,SIN3B,RPGRIP1L,PSD3,TNS2,PARD3,FLRT2,ZIC3,TRIM9" Drug 1682_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ABAT,ADCY6,AMPD2,PDXK,CFLAR,PTBP2,KRIT1,SRSF11,COL9A2,PPP6R2,KIAA0586,GIT2,DSCAM,SIDT2,RBM12,EML1,COQ7,EZH1,KAT8,B4GALNT1,SYT17,SRCAP,ZNF276,GLS,KCNMB4,MIA2,MPP2,NCAM2,SLC25A23,FSD1,GON4L,RAD51D,RALGDS,NEK11,SBF1,SLC20A2,CDK5RAP2,KDM4B,CDK19,PHLDB1,SIN3B,HIRA,VAV2,KLC2,ZNF32,SEMA3B,MPPE1" Drug 5400_UP S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ARID1A,PLA2G6,BIN1,SEMA7A,GAS7,BACH1,INA,CBFA2T2,CHRNB2,CNTFR,AKAP7,WHRN,COL9A3,ARHGEF10,ARHGEF4,CDON,HIPK3,EFNB3,DMTN,RASL10A,FYB1,CHL1,GLYR1,MAOB,ADAM22,MSR1,MYH7,MYO7A,NEUROD1,NOVA2,OPCML,NECAB2,PKN2,MAPK10,TCP11L1,OGDHL,MAPKBP1,EMC1,SYN2,SYT5,POPDC3,ZEB1,THBS4,THRA,PRMT8,ZIC3,KCNAB1" Drug 3010_DN Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "NDRG3,APAF1,ADAM15,SYNJ2,CACNB4,SCARB1,CHM,CSNK1E,SLITRK5,ZNF337,SMG7,HIPK3,FAM13A,PLXNC1,C3orf18,CAMKK2,CELF1,KCND3,IPO5,LSS,ENPP2,PLCB2,DEF8,PTN,TRIM68,RGS3,ARHGEF10L,CLIP1,FOXRED2,SCN2B,FAM214B,ARHGEF40,BTBD7,TMCC1,ZCCHC24,SS18,KAZN,CAMSAP2,TCF7L2,TNNT1,RBFOX2,NPL,ZNF32,ZNF45,ZNF74,MPPE1,PHTF2" Drug 7483_UP Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "APC,APOC1,ALDH4A1,KSR1,SYNJ2,CFAP410,ARHGAP33,CLGN,CRLF1,CSF1,CDON,EDNRA,CNNM1,EFNB3,CELSR3,EGFR,MBNL2,ING4,BAIAP2,FOXG1,PDLIM5,SYT17,TXNL4A,NR3C1,IPO5,MATK,MDM4,MIA2,AFF1,ZNF862,PDE4A,SERPINE2,MBOAT7,PPP2R5C,RIPOR1,RNASEL,SEC14L1,FAM214B,ZCCHC24,ZNF423,ZC3H13,PHLDB1,STX1A,MCF2L,KCTD2,WNK1,UBE3B" Drug 7444_UP Azaguanine-8 [134-58-7]; Up 200; 26.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "PLA2G6,CDK13,ALDH4A1,GYG2,SGCE,CFAP410,CA12,CHRNB2,NMT2,TBC1D5,MAGI2,DNM1,EIF5,MTSS1L,CAMSAP1,AGAP2,GPR153,ZNF44,TMEM8B,SRCAP,GNG4,RASSF8,SMAD1,MAP4,MATK,ADAM22,NPTX1,OPRL1,PDE4B,RAB3A,CCDC40,ZDHHC14,RGS4,TCP11L1,RPS6KA2,SNCA,RBM34,WDTC1,ZHX3,PHLDB1,VPS13A,CDK20,ZFP37,TFIP11,PRDM2,STMN4,SEMA3B" Drug 1724_UP Imipenem [74431-23-5]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "NDRG2,BRAP,CNTNAP1,ARNTL,NCOA1,TMEM184B,AKAP7,SEC31B,CRY2,CSF1,CSF1R,RUBCN,DCTN1,C2CD2L,SIDT2,PLEKHO1,FLT1,MAN1B1,ACOT7,KCNN1,MAN2A2,RETREG1,PLCB2,CNNM2,PTX3,RNASEL,TCP11L1,ITSN1,AMBRA1,BTBD3,ARHGEF40,CCDC88A,SLC15A2,EFHD1,ZCCHC24,DOK5,ERC1,IQSEC2,GSE1,SZT2,NACC2,PARD3,TNNT1,RBFOX2,FLRT2,NPDC1,XRCC4" Drug 4264_UP Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ABAT,SEMA6A,ASCL1,BACH1,CAMK2B,CCK,CNTFR,EDN3,SRPK3,ELN,RASGRP2,EFS,AFF2,DCTN2,EFCAB2,GNAL,GRM8,ATXN2L,HPSE2,HNMT,HTR2A,ICA1,KCND3,KCNJ5,LMO1,MOBP,NCAM1,NEFM,NTRK3,NUMA1,PDE4D,KHDRBS2,KLHDC8A,SCN2B,DOCK10,ST8SIA1,SLA,SNCA,ZC3H13,DDN,SPART,PCDHGB6,CRB1,SPX,TRO,ZMYND8,XRCC4" Drug 252_UP celecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "NDRG2,ADORA1,DGKD,ARNTL,ARSF,MTMR2,CFAP410,CAMK2A,ARHGAP33,ASIC3,TMEM59L,HOMER3,PCYT1B,NCOR2,DZIP3,MAML1,KLHL3,ST8SIA3,C3orf18,FGR,NSG1,GLS,GNAL,PTGDR2,NCKAP1L,KCNA4,MATK,MN1,FXYD6,NNAT,NOVA2,ENPP2,PACSIN1,MAPK8,KHDRBS2,GAL3ST4,RGS12,ASIC4,ASAP3,ABLIM3,KDM4B,SYN1,EXOC7,TNS1,WIPF1,SEMA3B,NUP214" Drug 2665_DN "ICI 182,780; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ABAT,MRTFA,TRMT9B,ANK3,PPFIA4,NUMB,MPDZ,CACNA1G,CACNA1A,NCOR2,CTIF,CDON,DYRK1A,MBNL2,MTSS1L,ERBB2,PIPOX,ST3GAL6,FHL1,SEPT9,POLL,GPM6B,SPACA9,GRM8,TJAP1,KHK,MAPT,MGAT3,AFDN,MYO6,NNAT,SLC11A2,SYTL2,CEP97,SCN2B,MRAS,CCDC92,ANKRD6,ARFGAP1,DDN,MAPK8IP3,EXOC7,OBSL1,TNS2,TNNT1,LMF1,XRCC4" Drug 5830_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "MTUS1,SEMA4G,DNAH17,ASTN1,SLC4A4,ATP2A2,ALDH7A1,KIF1A,CFAP410,CDC42,CRLF1,CNTN1,PDE4DIP,ARHGAP24,DCAF8,CNIH3,MFAP3L,DLG3,ABI2,STX2,ERCC2,FAM198B,DLC1,FYB1,GPM6A,ITIH2,KCNJ5,KIF5C,TAGLN3,MX1,NF1,ODF2,PDE2A,CCSER2,MAPK10,SAMD9,SEC61A2,RIC8B,PNMA8A,TMEM206,DOK5,KDM4C,SZT2,TEX15,UBE2H,VLDLR,FZD3" Drug 4227_UP Corynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "NLGN4X,ALK,PKP4,PPP4R4,CACNA1I,HAP1,MAGI1,FOXN3,CHI3L2,ASIC3,SUSD5,PYGO1,RIMS3,SV2B,RABGAP1L,DTNA,ABCC9,SNX29,CALCRL,OLIG2,BAIAP2,CAMSAP1,GAB1,PCDH17,ZNF276,GPM6B,ATF7,GRIK3,MOBP,NF1,NPR2,NTRK2,MTRF1L,PTPRB,PTPRN2,RGS4,RGS12,PNMA8A,LRRTM4,CXXC4,SNCA,TNIK,NFASC,TROVE2,EXOC7,ZNF34,TUBB1" Drug 3886_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.55E-03 1.00E+00 1.54E-02 1.75E-01 47 200 "ADORA2A,BIN1,CNTNAP1,APAF1,BRINP2,GYG2,CACNG1,ZFYVE9,CPS1,SPOCK2,ELMO1,RUSC2,TMCC2,RBM12,IRAK4,TNK2,KCNMB2,FGFR1,PDLIM5,TBR1,SIGLEC8,GLYR1,TDRKH,GRM2,KCND3,KCNH2,MAG,MAPT,MIA2,SLCO1C1,NUMA1,CDK18,CDK14,SERPINI1,MINDY2,ZSCAN32,PTPRN2,CPEB3,EPN2,FAIM2,KDM4B,ATP10B,VAMP1,TNS1,LAT2,MVB12B,KAT6A" Drug 1011_UP 15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 2.55E-03 1.00E+00 1.55E-02 1.76E-01 39 159 "AP1B1,BIN1,RGS20,BMP7,CAMK2G,ZFYVE9,TPP1,CREM,PDE4DIP,CTH,DNAJB6,F3,BAIAP2,IP6K2,IQCG,DPYSL4,FAM49B,FYN,GRB10,NR3C1,IL6R,MIA2,PIK3CD,RAB3IL1,RALGDS,MORC4,ZNF821,HSPA4L,SH3BGR,PPM1E,ZNF365,SLC6A8,TSPYL2,THSD1,JMJD6,POPDC3,TRIM2,VLDLR,ZFAND5" Drug CID000123395 EDSS Stitch 2.58E-03 1.00E+00 1.56E-02 1.77E-01 33 129 "SERPINA3,ACHE,APLP1,APOC1,BCHE,PTBP2,RUNX1T1,CD86,CLU,CNR1,CST3,CX3CR1,DAPK3,IL12A,KCNA1,LIFR,MAPT,MBP,MOG,MTR,MX1,NEFH,MAPK9,S100B,TRERF1,SPP1,SYP,TMEM121,ZFP91,NPL,TTPA,ZIC1,NETO1" Drug CID000002919 NSC107658 Stitch 2.58E-03 1.00E+00 1.56E-02 1.78E-01 67 306 "MYH7B,CDK13,SLC2A11,CALM1,ARHGEF25,SLC5A11,MYL6B,SLC4A7,CHRDL1,SLC29A4,EDN1,TUBD1,F3,PTK2B,TUBB3,TUBB4A,FCGR1A,FCGR3A,ACTL6B,AMOTL2,DCTN2,GCK,TUBA8,TUBA1C,ATE1,GSN,SLC2A6,HPSE2,MYLK2,TUBB2B,ITGAM,ASPRV1,AFDN,STK32C,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,OMG,CDK14,PKM,PRKCB,PRKCG,PRKCZ,PTHLH,PTK2,MYH14,SELL,MYO18A,FNDC3A,SLC2A5,SPTAN1,ACSBG1,ACTR6,TPM1,TPM2,TPM3,TPM4,TUBB2A,TUBB1,AMOT,SLC26A10,TUBA1A,PLD4" Drug 6795_DN Mebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASPHD1,ABHD6,ALCAM,PPFIA3,SLC4A4,KIF1A,CACNA1D,CBFA2T2,SRSF11,RCHY1,AKAP12,ARHGEF10,PDE4DIP,ARHGAP32,KIAA0586,SMG7,HIPK3,IRAK4,ING4,ANKMY1,FHL1,GLS,GRB10,HSD17B1,MAP4,MIA2,MPP2,NNAT,CNOT4,SLC11A2,RETREG1,PMP22,PRODH,CEP97,PAQR6,SH3BP2,ANKRD6,LIMCH1,MAPKBP1,ARHGAP26,NXT2,FAM168A,TFIP11,SEMA3B,FIP1L1,UBE3B" Drug 1857_UP Sulindac [38194-50-2]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "AGT,ALCAM,AMT,CDC42BPA,APC,CA12,SEPT7,CDC42,CDH10,ARHGAP33,SLC24A2,AKAP7,WHRN,KIAA0513,DAPK1,RHOBTB1,LPAR6,EIF4G2,ELN,ERCC2,FGFR1,ANKFY1,AFF2,CAMKK2,DISC1,CSDC2,POLL,GRIK5,PDE4A,PFKFB2,PPP5C,RGS10,TCP11L1,PAQR6,ITSN1,FUZ,PEX26,DOP1A,SP4,TSPYL2,CAMSAP2,RPGRIP1L,CDK20,CADM1,REEP1,MPPE1" Drug 5631_UP Clenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASIC2,BEGAIN,BIN1,APAF1,APBA2,AZGP1,KSR1,USP2,CD86,FOXN3,CHI3L2,LHX2,CHD5,NTM,ING4,DCTN2,CSDC2,HAS2,SCRG1,SHISAL1,KCND3,KCNJ5,MAG,MDFI,NCF2,NOVA1,OMG,PALM,PDE4A,PLCB2,PACSIN1,MAPK10,PTAFR,RASGRF1,RYR1,ASIC4,FRMPD1,CPEB3,SLA,SLC11A1,TSNAXIP1,SPTB,SYN2,DAAM2,XRCC4,JPH3" Drug 3191_DN Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ADCY6,AP2A2,LTBP4,FAM131A,PPFIA3,CFLAR,TAOK2,DZIP3,ZNF337,KBTBD11,MAMLD1,EDNRA,FGFR1,BAIAP2,PRKAG2,SEMA4D,CGREF1,COPS8,ITPKB,KHK,MAP4,MDM4,LYRM9,PDE3B,CCSER2,RETREG1,PRKACB,PRKAR1B,PTPRE,FBXW7,SMARCC2,KIF13A,ZHX3,CLASP2,TACC1,FBXW11,CRTC1,AHCYL2,ZNF34,KCTD2,KAT6B,ZKSCAN5,HIRA,ZNF74,EMSY,UBE3B" Drug 7033_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ANK3,SEMA4G,MARK4,SCAPER,MTMR3,GYG2,LDLRAD4,CALB2,SLIT2,ENTPD4,AKAP12,CSF1,MICAL2,DMPK,DTNA,SIDT2,PHF20L1,SORBS3,ING4,RRAGB,F5,DISC1,CNTRL,GRM1,KCNJ4,IPO5,MAP4,KITLG,PDE3B,PLTP,GRAMD1C,PRODH,PTCH1,PEX5,PDZRN3,PLCB1,ROBO3,EXOC7,CUX2,TPD52,HIRA,PLPPR2,VAV2,LAT2,KCNK12,NDRG4" Drug 3504_DN Asiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "SERPINA3,ASPHD1,APBB2,ADAM15,BTRC,SYNGR3,B4GALT6,RAB28,CSF1,PDE4DIP,CTH,RIMS3,INTS1,DBN1,SMG7,PARD6A,OPTN,EFNA3,PRELID3A,HBS1L,INPP1,KIF2A,KITLG,NF1,PC,SLC25A23,POLG,TMEM104,RIPOR1,EMID1,WLS,SH3BP2,ANKRD6,CDK5RAP2,SS18,AJAP1,ARHGEF9,DNMBP,TRIM2,TMEM121,SLC44A1,ZMYND8,VAV1,WNK1,VPS35L,SSPN" Drug 5923_UP PF-00875133-00 [351322-64-0]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASIC1,ADORA2A,BIN1,APBB2,GAS7,PDE8B,BRINP2,ADAM15,PLAA,TPP1,CTH,MFAP3L,RUSC2,DTNA,PLXNC1,RASGRP2,DLC1,FER,FGFR1,FYN,GNG3,ELOVL5,KPNA5,ADAM22,ZNF862,NDUFA5,NNAT,SERPINE2,PLEC,MBOAT7,SAMD9,WDR25,PTPRN2,FBXW7,ASIC4,ZNF821,ASAP3,ZNF365,FAM214B,SOX2,MAPK8IP3,ELOVL4,LAT2,XRCC4,SLC30A3,MVB12B" Drug 6235_UP Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ARID1A,ADCY6,ADRA1D,SEMA6A,MARK4,ASPH,ALDH4A1,ATM,SLC4A4,CADM3,BACH1,CDK5R1,SYNJ2,CFAP410,ARHGEF2,CDH10,ZFYVE9,CLCN3,SIPA1L1,PDE4DIP,RIMS2,TBC1D5,DAPK3,PRELID3A,CACFD1,NR3C1,GRM8,ITPKB,LSS,MSR1,ZNF862,NDUFA5,PPP5C,SAMD9,WDR25,RAB5B,NEK11,ZCCHC24,TSNAXIP1,ZBTB43,TRIM2,TK2,ZNF384,ZMYND8,VIPR2,MPPE1" Drug 2336_DN Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "BRAP,APP,ASPH,SLC4A4,ADAM15,CA12,CAST,SCARB1,SOCS6,QKI,VCAN,CX3CR1,ARHGAP32,SGSM2,SORBS3,CELF1,OGA,TRAF3IP2,DHX35,ICA1,ITGAM,ITPKB,KLC1,SMAD1,MAP4,OGG1,PDE3B,RETREG1,GON4L,RAB3A,CCDC25,FBXW7,TCP11L1,DOCK10,ARHGEF40,MAPK8IP3,DIP2A,GSE1,ANKRD12,FLRT2,PLPPR2,ATP6V0E2,NT5M,URM1,TIGD6,AAAS" Drug 7054_DN SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "NCOA1,CFLAR,SCAPER,RAB28,QKI,ARMC8,NCOR2,EDRF1,DBT,ATN1,HIPK3,EGFR,DMTN,LRRC23,F3,FHL1,CGREF1,NCKAP1,GLYR1,GPD2,STON1,GPER1,MAP4K5,HNMT,HSF2,JAK2,KIF5C,NFYA,NUMA1,PDE3B,MINDY2,PPP5C,PRKAR1B,CEP97,RGS3,ROM1,TCP11L1,SAFB,ZNF821,ZCCHC24,KLHL7,TACC1,TRIM2,TMPO,RBFOX2,VSNL1" Drug 2113_UP Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ANK3,PPFIA4,APC,APP,KIF1A,HIP1R,CHRNA4,HAPLN1,ARHGEF4,SNPH,ARNT2,DLG3,DTNB,PLEKHA1,EN2,EZH1,SEMA4D,DLL3,WASF3,ZNF276,POLL,KCNMB4,INPP5B,KCNJ4,NPPA,PLXNB1,POLG,ACSS3,KCTD17,SLC4A3,PEX26,SMARCD3,VAMP1,TCF4,TCF7L2,TRIM2,SYNE1,PSD3,TMOD1,TPM1,ZKSCAN5,UBTF,XRCC4,SPHK2,WNK1,SEMA3B" Drug 7448_UP Bacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "BIN1,CDC14B,PPP4R4,CFLAR,CAMK2G,USP2,CBFA2T2,CDH10,MAGI1,FADS2,SLC4A8,PDE4DIP,CTH,OGA,DISC1,SRCAP,USP19,GLYR1,RNFT2,HLF,IGSF1,OPCML,RETREG1,PLXNB1,PPP2R2B,PPP2R5C,RGS4,GSTCD,RPS6KA2,SLC1A7,SLC11A1,SLN,SNCA,WDTC1,UNC5B,BEX1,STX1A,PLCB1,ANKRD12,ZNF34,KCTD2,PIK3R5,ZNF32,REEP1,SLC30A3,SCG2" Drug 6124_UP Cyproterone acetate [427-51-0]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "BCAR3,BIN1,ASPH,MYRF,SLIT2,CLCN4,CREM,NCOR2,ABCG1,RIPOR2,SNPH,DAPK1,SV2B,ST8SIA3,EDN3,EFNA3,EIF1,MTSS1L,SORBS1,GPR153,GNAO1,PRUNE2,ATF7,GRIN1,GRM1,GRM7,HAS2,KCNJ4,FXYD7,NPTX1,NTRK2,CLDN11,PCSK5,PLCL1,CNNM2,GAL3ST4,SYNDIG1,ASAP3,SLC1A3,SHANK2,KIF13A,ATP13A2,CHST8,TUBB1,SH3GLB2,MAP3K12" Drug 7198_DN Podophyllotoxin [518-28-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ARID1A,ADD3,AK2,ARHGDIG,FOXN3,RAB28,HOMER3,PICK1,CREM,LRIG1,SDC3,MED12,PHF20L1,EIF4G2,ZNF589,GABRA2,SESN1,GLYR1,MUM1,KHK,SCAMP5,NF1,CNOT4,NUCB1,OGG1,PCDH9,PRKAR1B,PTCH1,RAB3IL1,CEP97,RAD51D,FOXRED2,SGK1,SH3BP2,RAB3GAP1,SPATA7,ZHX3,UNC5B,DIP2A,ARHGEF9,EXOC7,IQCE,TCF7,RPRM,HPS4,TIGD6" Drug 2973_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ABAT,MTUS1,CASK,ARRB1,CDK13,ASPH,CD86,HOMER3,MAGED1,CSF1,SIPA1L1,VCAN,PDE4DIP,ZNF337,TM9SF4,SPATA2,FAM13A,LPAR6,FGFR1,FLT1,ERAP1,SEPT9,SRCAP,SLC2A6,MAP4,MX1,CNOT4,PDE3B,PDE4D,ENPP2,GON4L,PTPRN2,FAM184A,ATXN1,RASA3,DZIP1,SLC2A5,FAM214B,DOP1A,SPP1,UNC5B,TSPYL2,ITPRID2,ZEB1,FLRT2,NT5M" Drug 1156_UP prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "AP2A2,GAS7,CASK,ARNTL,PDE8B,NCOA1,ALDH4A1,SYNJ1,ARHGEF7,LDLRAD4,SCARB1,ZMYM4,CHRNA4,AKAP7,ARHGEF10,CTH,KIAA0753,RUSC2,RCAN1,DTNA,F5,CAP2,SEPT9,VSIG4,ICA1,MAP4,MIA2,MITF,P2RX7,PDE4D,ENPP2,SERPINE2,ZFYVE21,TMEM231,FNDC3A,SPP1,THSD1,SS18,RGL1,SYT11,SLC44A1,PARD3,TFIP11,ZNF225,PRDM10,RNF146" Drug 5313_DN Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "RBM10,ARRB2,NCOR1,FAM169A,RUBCN,USP6NL,DCTN1,DNM1,APH1A,PLEKHA1,EZH1,FGFR3,ANKFY1,CGREF1,B4GALNT1,BTN2A1,IL6ST,KIF5C,MEIS2,MIA2,OGG1,OPA1,PCDH9,RETREG1,SMIM7,POLG,CNNM2,TMEM231,MYH14,ROBO1,CLSTN1,SMARCA4,TMCC1,KDM4B,ZSWIM8,ZBTB43,ARHGEF9,TCF7,TIAM1,BEX4,TP53BP1,HIRA,VGF,ZNF32,MPPE1,EPM2A" Drug 1273_UP Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ABHD6,ALAD,APP,PPP4R4,SYNJ2,CLGN,TAOK2,ZFYVE9,TM9SF4,SGSM2,RABGAP1L,DLG4,DTNA,TSPAN5,FAM13A,ING4,RASGRP2,ECSIT,FLT1,SEPT9,GFER,GRIK5,PADI2,HRH3,MAP4,MIA2,N6AMT1,NUMA1,P2RX7,KCTD15,RC3H2,POU6F1,PTAFR,CCDC40,SEMA6D,CPEB3,EPN2,DDN,NCDN,STX1A,IQCE,TCF7L2,ATP13A2,LAT2,PRDM2,GDPD5" Drug 3392_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "NDRG2,BIN1,PPP4R4,SYNJ2,MTMR3,GYG2,C5,USP2,ARHGEF2,ADGRG1,CHM,ARHGEF6,PICK1,SLC4A8,SORBS3,ELN,VPS13B,SPEG,IQCG,SEMA4D,GAD2,RND1,GLYR1,IL6ST,INPP5B,VWA5A,MMP16,LYRM9,OGG1,CDK14,NLE1,PPP2R2B,MAPK7,MAPK8,RGS10,RASA3,ZKSCAN3,SNCA,ARHGAP26,THSD1,EXOC7,TK2,TMOD1,REEP1,MAP3K12,KAT6A" Drug 3893_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "MRTFA,KCNAB2,APLP1,CDK13,ALDH4A1,ATM,CAMK2B,CAMK2G,DNAJB5,NECTIN3,AKAP12,ZNF804A,KBTBD11,PLXNC1,DMTN,STX2,ERCC2,FGF12,FGFR1,GLYR1,GRM8,INPP5B,KHK,TM6SF1,KITLG,MMP16,ADAM22,NPPA,OGG1,PDE4A,PLCD1,PRKCB,MAPK10,ELOVL2,FAM120C,SELL,RASA3,FNDC3A,ZKSCAN3,SMARCD3,WDTC1,SPTAN1,STX1A,PLCB1,SMG6,NUP214" Drug 2916_DN Letrozole [112809-51-5]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "BRAP,ANK2,ZBTB10,CD86,ENTPD6,SOCS6,HOMER3,VCAN,CX3CR1,C2CD2L,ATP2C1,GART,GLYR1,ARHGAP19,PAXBP1,MX1,NDUFA5,NF1,NUCB1,SETD4,OGG1,OLR1,ENPP2,GPR85,PLCB2,STRN3,PILRA,SNRK,TMEM104,TMEM231,RXRA,MAPK12,PPM1E,FBXO11,ARHGEF40,KBTBD4,KIF21B,EXOC7,DMXL2,SYNE1,KAT6B,LAT2,WNK1,NT5M,UBE3B,NLRP3" Drug 4433_DN 2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "RALGAPA1,MRTFA,CDC42BPA,APC,APOC1,ADAM23,BAIAP3,LHX2,NRXN3,CREM,AATK,VCAN,SLITRK5,RUSC2,SPOCK3,ECM2,ING4,NCALD,SCML2,PRELID3A,GRIK5,GRM1,PADI2,ICA1,KCNJ5,VWA5A,MAPT,MIA2,MMP16,NF1,PFKFB4,PLCB2,WDR25,CNTLN,TMEM206,SELL,BCAN,SPTB,LHPP,TROVE2,MLC1,TBCEL,TIAM1,TNS1,VIPR2,EVI5" Drug 6059_DN Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASIC1,ARID1A,SRPX,APOC1,ARRB1,CFLAR,CACNA1I,USP2,CBFA2T2,ARHGEF2,PLEKHB1,RCHY1,NECTIN3,PDE4DIP,MAML1,HIPK3,EFNA3,ZNF589,FGFR1,FOXG1,C1orf61,SRCAP,GRIK5,GRM1,MAP4K5,KIF5C,MAP4,MITF,MMP16,ADAM22,ZNF862,SLC25A23,PRKAB2,PRODH,ATG16L1,SBF1,SLN,SNCA,WDTC1,PHLDB1,ATP11A,DICER1,CHST8,KCNK12,PRDM2,MARCH8" Drug 6918_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "NME5,ST3GAL5,ARHGEF7,SCAPER,CLCN3,NMT2,SLC4A7,NECTIN3,OSBPL3,NR1D2,RBM12,EIF4G1,TNK2,SEMA4D,GLS,GPR37,PCLO,NR3C1,HPS5,AGFG1,JAK2,KCNMA1,PDGFRA,PIK3R1,LRP12,MED1,PRKACB,MAPK7,RALGDS,SEC61A2,SEC14L1,PPP1R9A,ST6GAL1,ELMO2,KDM4B,ANKRD12,TBL1X,TCF4,TGFBR3,ZNF34,NR2C2,HIRA,LMF1,SF1,ZBTB38,WNK1" Drug 5626_DN Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ACTN2,NDRG2,SEMA6A,GAS7,ATP6V0A1,MTMR3,GYG2,PDE4DIP,EDRF1,JAKMIP2,MFAP3L,DRD1,EIF4G2,STX2,ZNF589,CGREF1,OGA,HBS1L,MALT1,GLS,MSL3,FERMT2,CACFD1,NF1,NPTX1,NLE1,SLC25A23,PLPPR1,ZNF821,ZFP30,ASAP3,AMBRA1,WDTC1,DOK5,SEPT8,PLCB1,TNS2,AHCYL2,CHST8,TPD52,RUNDC3B,ZNF711,SYNC,MAP3K12,GDPD5,SSPN" Drug 2942_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "RBM10,ARID1A,PLA2G6,KCNAB2,KIF1A,ARHGEF1,LHX2,CLTB,NIPBL,CLOCK,CREM,CSF3R,PPP1R16B,TM9SF4,INTS1,DCTN1,GAB1,TRAF3IP2,GATM,RUNDC3A,ZNF276,INPP1,JAK2,LSS,SMAD1,AFDN,NUMA1,PTAFR,BSDC1,FBXW7,GALNT10,ITSN1,NUBPL,DHX30,SMARCA4,SPTB,IQSEC2,THSD1,PRRC2C,VAMP1,PDLIM2,SZT2,TK2,PIK3R5,TRPC1,WIPF2" Drug 6762_DN Cefotiam hydrochloride; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "MRTFA,ATP1A3,SLC4A4,KIF1A,ADAM23,CFLAR,CANX,ARHGEF1,CBFA2T2,CHM,CPS1,CREM,ENTPD4,NCOR2,MICAL2,TBC1D5,BRINP1,DLG3,EGFR,ETV1,C1QL1,GLYR1,GPM6B,RASSF8,SCIN,IL6ST,JAK2,KIF5C,NDUFA5,NUCB1,NUMA1,MINDY2,PRKAR1B,RAB3A,RALGDS,RGS10,CLIP1,SBF1,NXT2,ASTN2,TRIM2,SYNE1,TIAM1,TSC2,OSBP2,PHTF2" Drug 4103_DN Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "PLA2G6,LTBP4,MRTFA,CAPRIN2,SCAPER,GYG2,STOML1,DBN1,MAGI2,SUGP2,ING4,ZNF589,PRKAG2,CAMSAP1,FHL1,SEMA4D,TRAF3IP2,GAD1,HBS1L,DISC1,GLYR1,RAB30,ELOVL5,IL6ST,INPP5B,ITIH2,KCNH2,LSS,KITLG,MPP2,ADAM22,NEK1,NFYA,CNOT4,PLCD1,PTPRO,FUZ,SLC1A7,ZCCHC24,CLSTN2,THSD1,AJAP1,TNS2,ZNF34,CABIN1,ZBTB14" Drug 2895_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "KCNAB2,APBB2,AQP6,ATM,CFLAR,SCAPER,BAIAP3,CACNA1D,CACNA2D1,CAMK2B,CDO1,CLGN,TAOK2,CPS1,NCOR2,AATK,SPOCK2,JAKMIP2,GSDME,EFNB3,DLC1,FOXG1,GRIK5,HLF,ICA1,KIT,MAOB,MSI1,NDUFA5,NUMA1,SERPINE2,PLEC,LRP12,PRODH,SAMD9,KLHL11,EMID1,IQSEC2,ATP10B,KIAA0930,PCDHA6,HIF3A,TMEM121,TPM2,ZMYND8,KCNK12" Drug 6870_DN SC-560; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "AMT,CDC42BPA,EPB41L5,GAS7,ADAM15,BTRC,CA4,CACNA1D,KYAT1,CHRNB2,CHD1L,ST18,RASSF2,DAPK3,SMG7,ATN1,DUSP9,FCF1,EFNA3,EML1,LRRC17,KIAA1109,DISC1,GLYR1,ATXN2L,HNMT,HSF2,TJAP1,KCNJ3,KCNN1,ADAM22,CNOT4,NUCB1,NUMA1,SERPINE2,PLCD1,TNPO2,MAPK8,PEX5,ATG16L1,FNDC3A,ARC,TMEM121,PIK3R5,RBFOX2,RUNDC3B" Drug 1944_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; PC3; HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "PKP4,APOC1,ASPH,ZBTB10,SLC4A4,FUBP1,GYG2,CA12,KRIT1,SOCS6,CHN2,SLC4A7,CTH,HDAC9,TOX,SPATA2,RUSC2,DTNA,DUSP9,EPB41L1,SPEG,ACSL4,SEC23B,NCKAP1,COPS8,RNFT2,HAS2,KLF12,PIK3R1,KCTD15,PLCD1,RPRD1A,AMBRA1,TMCC1,PEG10,RBM26,GSE1,EXOC7,AGTPBP1,TCF7L2,NSD1,SEZ6L,DNAJC12,VIPR2,MVB12B,DPF3" Drug 6131_DN Dubinidine [22964-77-8]; Down 200; 14.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ACTN2,AP2A2,MTUS1,MRTFA,CDC42BPA,PPP4R4,MARCH3,CAPN3,USP2,INA,CRMP1,EDRF1,DAPK3,SIDT2,COQ7,PIPOX,ANKMY1,GABRA4,SEPT9,GLYR1,GLS,SPACA9,VWA5A,MAP4,NPR2,OCRL,OMG,PDE4B,SERPINE2,CCSER2,RETREG1,PLCD1,PRKCZ,PEX5,RIPOR1,RAB3A,ITSN1,CPEB3,DZIP1,FAM214B,RAP1GAP2,THSD1,PSD3,PLPPR2,ZIC3,REEP1" Drug 5702_DN GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "APBB2,APC,EPB41L5,PPP4R4,ALDH7A1,KIF1A,CA4,B4GALT6,RAB28,HOMER3,SIPA1L1,DZIP3,SDC3,NOS1AP,DAPK3,SPOCK2,ARMCX2,PARD6A,DRD1,RCAN1,TOM1,EML1,EN2,STX2,BAIAP2,HBS1L,POLL,CNTRL,KIF5C,LSS,MMP16,MPP2,ADAM22,NF1,SAMD9,TMEM104,RIPOR1,CEP97,ASAP3,FUZ,SLCO1A2,TBCEL,WSCD1,PSD3,TMOD1,PHTF2" Drug 1706_UP Naproxen [22204-53-1]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "KIDINS220,AMPD3,APP,ASPH,SCAPER,RUNX1T1,SH2B1,SDC3,CTH,GPRASP1,FBXL5,NR1D2,APH1A,SORBS3,EPB41L1,LRRC23,F3,PDLIM5,TXNL4A,SPIN1,MSL3,GPD2,INPP5B,KCNN2,KITLG,NEK1,NF1,RAD52,BSDC1,RGS12,CLIP1,SGK1,FBXO11,PEX26,PPP4R3A,ARFGAP1,WDTC1,CEP68,TTBK2,PRRC2C,VPS13A,ARC,SEMA4A,VIPR2,ZNF45,GAN" Drug 7543_UP DNA-PK Inhibitor III; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "AP2A2,CACNA1D,CAMK2B,CDH18,TPP1,DZIP3,MFAP3L,HP1BP3,DTNA,DTNB,DMTN,GPR153,DISC1,GLYR1,GPR37,KIF5C,LMO2,LSS,MAN2A2,MBD1,ZNF862,NNAT,CNOT4,SLC11A2,RETREG1,LRP12,MBOAT7,RAB3IL1,RALGDS,CARF,FBXO11,ZNF365,LIMS2,EMC1,STX1A,VAMP1,PLCB1,SMG6,SZT2,PARD3,METTL3,TRPC1,VAV2,LMF1,ZNF45,RNF170" Drug 2446_DN Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASIC1,ARID1A,ADRA1D,APC,SYNJ2,CAPN3,PLAA,NMT2,ARHGEF10,CSNK1E,DGKG,SV2A,EFNB3,ING4,PCOLCE2,CDKL3,F5,ZNF589,FOXG1,GABRA2,SEPT9,INPP5K,GATM,LPAR4,SPACA9,MAN1B1,AGBL5,MAP4,N6AMT1,NUMA1,MAPK10,TMEM104,RAP1GAP,ZNF493,ZDHHC14,EMID1,SH3BP2,PEX26,DDN,JMJD6,KAZN,ADGRL3,TCF7,THRA,LMF1,FTSJ1" Drug 1138_DN phentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ABAT,OSBPL1A,CDK10,NUMB,BCL2L2,BLM,LRRFIP1,FOXN3,ABCG1,MICAL2,ARHGAP32,ZNF337,SMG7,DMTF1,FCF1,SEC23B,ANKFY1,TACC2,INPP5K,BTN2A1,KIF3A,CLASRP,JAK2,OGG1,PDPK1,RC3H2,KLK6,ARID4A,DCUN1D2,CHD9,NUBPL,RAB3GAP1,ELMO2,TTC17,ZBTB43,FRYL,SIK3,SIRT1,PARD3,ZNF384,TRIO,ZMYND8,CLDND1,PARP6,MPPE1,NUP214" Drug 2624_UP "Clomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "MRTFA,GAS7,RASL11B,ALDH4A1,SCAPER,CFAP410,CA4,CAMK2B,ZFYVE9,FADS2,AKAP6,HINFP,NCAN,CNTNAP2,RIMS2,HDAC4,MFAP3L,HSD17B14,FOXG1,SRCAP,ITGAM,KCNQ3,MIA2,NDP,NDUFA5,NOS1,NPPA,PIK3CD,MBOAT7,MINDY2,PTPRN,TTLL7,ASAP3,FAM214B,SLN,RIMS1,ZCCHC24,SPP1,KDM4C,ARHGAP26,IQSEC2,SYT5,EXOC7,CLIP2,SLC13A3,KCNAB1" Drug 5004_DN Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ADCY6,CDC42BPA,APC,NCOA1,MPDZ,BCL7A,ST3GAL5,BTRC,AP4M1,B4GALT6,LHX2,NIPBL,PDE4DIP,KIAA0586,SMG7,DLG3,GNE,DTNA,EFNA3,EML1,TAOK3,FGFR3,DPYSL4,MALT1,GPR37,CNTRL,INPP5B,ADAM22,MYO9A,NF1,RIPOR1,ROM1,CLIP1,ITSN1,SLC1A7,PDZRN3,TACC1,IQCE,TRIM2,CLASP1,ZMYND8,SSBP2,ZIC1,ZNF24,ZNF74,EPM2A" Drug 2464_DN Probenecid [57-66-9]; Down 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "BIN1,KCNAB2,CDK10,ARRB1,BACH1,SLC25A14,SCARB1,NMT2,QKI,CREM,PLXNC1,TUBD1,LRRC23,NCALD,KAT8,ZNF589,ATXN2L,TJAP1,MAP4,SCAMP5,AFF1,ZNF862,NF1,NUMA1,SETD4,PIK3CD,NLE1,PLCD1,RNASEL,MYH14,SEC14L1,CCDC88A,RAP1GAP2,TROVE2,CAMSAP2,TCF4,SZT2,CRTC1,CBX5,TMPO,KCTD2,RBFOX2,UBTF,FLRT2,PRDM2,PHTF2" Drug 3721_DN Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "KIDINS220,APOC1,ZFYVE9,HOMER3,VCAN,DZIP3,GPRASP1,TBC1D5,TMCC2,FGF1,ANKFY1,PRELID3A,CGREF1,MSL3,EML4,CACFD1,KLF12,KCNMA1,KIF5C,NEK1,NF1,NPR2,PTK2,FAM120C,ROM1,FBXW7,ZNF821,ASAP3,DOCK10,FAM214B,CCDC88A,SLC20A2,ZNF667,SNCA,TNIK,EMC1,CEP68,COBL,SZT2,CHST8,TMPO,TRIO,LMF1,MAP3K12,SEMA3B,GAN" Drug 4723_UP Methotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "ASIC1,NME5,KCNAB2,GAS7,PLA2G4C,CFLAR,BAIAP3,PLEKHB1,QKI,CREM,CSF1,ATRNL1,FAM169A,GIT2,EFNB3,EIF4G2,ZNF589,KIAA1109,HPCAL4,FUT9,GABRA2,GAD2,DISC1,C1QL1,GLYR1,GNAL,GRB10,RAPGEF1,GUCY1A2,ITIH2,KCNJ3,KCNMA1,VWA5A,MEF2C,MID1,MMP16,KCNK10,STRN3,LRP12,AP1AR,CCDC88A,PLCB1,TRIM2,HIF3A,EMSY,SCG2" Drug 5448_DN Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "LTBP4,PPFIA3,MARK4,SYNJ2,ZFYVE9,DAPK3,RUSC2,DSCAM,MRNIP,DMTN,KIAA1109,FGFR1,INPP5K,GNAS,JAK2,KCNF1,KPNA5,ADAM22,NF1,PRODH,PTHLH,PTPRE,NKAIN1,SLC1A7,SLC6A8,ZKSCAN3,SLN,UNC5B,SPART,LHPP,CAMTA2,SS18,VAMP1,ATP11A,MCF2L,IQCE,TCF7L2,TRIM2,PCDHA6,TRPC1,ZKSCAN5,SPHK2,MAP3K12,GDPD5,KAT6A,RNF170" Drug 5077_DN Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "NME5,KCNAB2,RGS20,BTRC,MAP7,CDC42,FOXN3,TAOK2,CLCN4,CHD1L,EDIL3,FAM13A,ING4,PLEKHO1,EPHA5,CDKL3,ETV1,VPS26C,PDLIM5,TMEM8B,INPP5K,GNAS,SHISAL1,MIA2,PAK3,PBX1,PLCD1,SLC25A23,SNRK,TMEM104,RPS6KA2,SCN8A,DZIP1,SLC6A8,SLC22A4,TMCC1,CAND2,SEPT8,VPS13A,CRTC1,TK2,TPM2,WIPF1,MAP3K12,PHTF2,DPF3" Drug 4139_UP Nadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "CDC7,ALK,ASPH,N4BP2L1,ADAM15,SYNJ1,SYNJ2,CACNA1I,CFAP410,KRIT1,ARHGEF1,CLGN,NCOR2,CSF1R,CST3,EDRF1,DMTF1,DRP2,ATN1,RBM12,CAMSAP1,PTGDR2,HNMT,HSD17B1,ICA1,KCNJ3,ADAM22,NF1,PLXNB1,PPM1B,MAPK7,ATXN1,PPP1R9A,FBXO11,SHANK2,SMARCA4,LIMCH1,SP2,PEG10,AJAP1,EXOC7,KIAA1107,TRIM2,UBE3A,HPS4,ITM2C" Drug 4172_UP Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "APC,ATP1A2,CFLAR,CACNA1G,ARHGEF2,AKAP6,MICAL2,CNTNAP2,BRINP1,RUSC2,DMPK,EDN1,C3orf18,STX2,EFS,CORO2B,FHL1,NSG1,FYB1,GABRA5,ALDH1L1,GCNT2,GUCY1A2,HAS2,KCNC1,KCND3,AFDN,MMP16,NCAM1,NOVA2,NTRK2,SAMD9,PTPRB,PPP1R9A,FRMPD1,SLC11A1,IZUMO4,ATP10B,ATP11A,DOCK9,HIF3A,TEK,LILRA4,WIPF1,ZNF711,SLC17A7" Drug 4234_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "PLA2G6,ALK,TRMT9B,AMPD3,CDK10,ALDH7A1,ST3GAL5,BAIAP3,CFAP410,CAMK2B,CBFA2T2,CDC42,CDH10,VCAN,DYRK1A,FCF1,SIDT2,COQ7,ETV1,TRAF3IP2,TMEM8B,USP19,HNMT,KIF5C,MATN3,CNOT4,NUMA1,PAK3,PFKFB2,SLC25A23,POLG,PTPRB,FAM184A,ZNF821,KIF13A,RBM34,TSNAXIP1,DOK5,SPTAN1,CDK19,SS18,TRIM2,TEX15,THRA,VGF,NUP214" Drug 4611_DN Tyloxapol [25301-02-4]; Down 200; 4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.59E-03 1.00E+00 1.56E-02 1.78E-01 46 195 "APP,ARRB2,ADGRB2,LDLRAD4,TAOK2,SLC4A8,BAG4,TM9SF4,MFAP3L,KIAA0753,SLC12A6,ATN1,RCAN1,RRAGB,ST3GAL6,FGFR1,ANKFY1,CINP,TRAF3IP2,GAD1,COPS8,CACFD1,KIF5C,MX1,PALM,PLXNB1,RC3H2,MAPK7,WDR25,RAD52,FRMPD1,SLC1A7,KBTBD4,SMARCD3,ZNF415,TMCC1,VPS13A,EXOC7,SMG6,KIAA0930,ARHGEF12,RIMBP2,OSBP2,TFIP11,EVI5,HPS4" Drug CID000001234 gallopamil Stitch 2.62E-03 1.00E+00 1.57E-02 1.79E-01 20 67 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CACNA2D2,CACNG7,CACNG3,CACNG2,PKD1,QDPR,RYR1,RYR3,TPCN2" Drug CID006419303 purealin Stitch 2.62E-03 1.00E+00 1.58E-02 1.79E-01 18 58 "MYH7B,CALM1,MYL6B,DNAH9,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO9A,MYH14,MYO18A,TPM1,TPM2,TPM3,TPM4" Drug 4663_UP Clioquinol [130-26-7]; Up 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "MRTFA,EPB41L5,BRINP2,AZGP1,GPR37L1,CHRNA4,VAX2,COL9A3,CSF1,C2CD2L,ATN1,DSCAM,EFS,ABCA8,ALDH1L1,RND1,CACFD1,ADAMTS8,GRM1,SOX21,GPR45,PTGDR2,KCNC1,MT1M,MX1,NEFM,SLCO1C1,PDGFRA,SPATA6,PROX1,SUSD4,RGS4,RGS12,HKDC1,SLA,KIF21B,SOX10,ARC,PCDHGA10,SPX,ICAM5,CDK20,PRDM2,MVB12B,PARP11" Drug 3458_UP Ebselen [60940-34-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "AMPD3,BIN1,KCNAB2,MARK4,SLC4A4,ATP2B2,CFLAR,CACNB2,ASIC3,SLC22A6,ENTPD4,SH2B1,CSF1R,C2CD2L,MAGI2,GSDME,EDNRB,SIDT2,PLXNC1,ATP8A1,FECH,ERAP1,MSL3,ELOVL5,KCNJ5,SLC11A2,NUMA1,PFKFB2,EPN1,PLTP,SAMD9,RAB3A,GTDC1,SH3BGR,ZHX3,UNC5B,DIP2A,CHST8,TRIO,TRPM2,REEP1,SLC30A3,EMSY,EVI5,MVB12B" Drug 7519_UP "11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "ASPHD1,NME5,PLA2G6,BIN1,ADGRB2,CFLAR,FUBP1,CFAP410,MAP7,CACNA2D2,PLEKHB1,ARMC8,WHRN,AKAP12,CSF1,CSNK1E,CTH,NOS1AP,DAPK3,PARD6A,DPH1,OPTN,DMTN,FER,CGREF1,MPP6,GAD1,GART,USP19,GRIK5,BTN2A1,INPP5B,JAK2,ELOVL2,PTPRH,RGS4,TCP11L1,ASAP3,SLC22A4,TROVE2,TEX15,LAT2,SEMA3B,KCNAB1,MPPE1" Drug 4274_UP Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "CDK13,ASTN1,SLC2A11,ADGRB2,BAIAP3,CACNG1,CAMK2B,LDB2,ARHGAP33,CLCN4,DNAJB5,CTIF,DLG4,ATN1,HIPK3,SORBS3,ELN,REEP2,FGFR1,SEPT9,ALDH1L1,GFER,GRM7,ATXN2L,LSS,PACRG,MMP17,NUCB1,PBX1,PIK3CD,RETREG1,PKM,MAPK7,BCAN,SLC2A5,SLC11A1,HECW1,VAMP1,ATP11A,MCF2L,TAL1,SZT2,PCDHA5,OSBP2,MVB12B" Drug 2299_DN Kawain [500-64-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "ADD1,MARK4,ATM,CFLAR,GYG2,ARHGEF1,CLCN3,VAX2,FAM169A,HP1BP3,FCF1,EFNA3,EFNB3,SUGP2,ACSL4,FAM49B,HTATSF1,CNTRL,NR3C1,HNMT,IL6ST,INPP5B,ITPKB,KCNJ3,KCNN2,MAP4,MBD1,GIT1,NOS1,PKN2,GON4L,SLC25A36,PPP4R3A,CLASP2,POGZ,ST5,NCDN,PHLDB1,TACC1,TCF7,PCDHA6,KAT6B,ZMYND8,ZKSCAN5,WNK1" Drug 1343_DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "GRAMD1B,ADORA3,AK2,C1QTNF3,ATM,STX16,CFLAR,MTMR2,LDLRAD4,CAPN3,MAP7,VCAN,TBC1D5,KIAA0586,DBN1,HP1BP3,DPH1,VPS26C,ANKFY1,FAM49B,ZNF44,ARFIP1,PSRC1,LILRA2,ICA1,TJAP1,MEF2C,CCSER2,SNX10,PLEC,MINDY2,PPP3CB,SAMD9,SIDT1,PTAFR,FNDC3A,SLA,ZCCHC24,ZHX3,NXT2,TPD52,ZMYND8,MPPE1,PHTF2,ACTR3B" Drug 2887_UP Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "AK2,BIN1,APBB2,APOC1,RGS20,ATM,SLC2A11,CFLAR,CACNA1I,CA4,CA12,CBFA2T2,TAOK2,ARMCX2,RUSC2,ERBB2,VPS26C,FAM198B,PTK2B,BAIAP2,OGA,ALDH1L1,SRCAP,LYVE1,GPR37,ICA1,IL6ST,KCNJ3,KCNJ5,MIA2,NF1,NUMA1,PLP1,SLC25A23,MTRF1L,CEP41,RASA3,DOCK10,ARHGEF40,LIMCH1,TSNAXIP1,ZBTB43,TACC1,DMXL2,HIRA" Drug 3468_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.64E-03 1.00E+00 1.59E-02 1.81E-01 45 190 "RALGAPA1,C1QTNF3,AMT,ARHGDIG,ARRB2,ATP6V0A1,GYG2,ENTPD4,ARHGEF10,ARHGEF4,MAML1,GNE,PLEKHA1,FHL1,RND1,GLYR1,STON1,HPSE2,ITPKB,KCNF1,LMO2,ADAM22,FSD1,RAB3IL1,FAM184A,ZDHHC14,GSTCD,ROBO1,WLS,PEX26,EPN2,SMTN,BTBD7,SLC20A2,COA1,SMARCD3,KDM4B,SPTAN1,PLCB1,DMXL2,PSD3,ZNF34,SLC44A1,WNK1,EMSY" Drug 3945_DN Helveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.69E-03 1.00E+00 1.60E-02 1.82E-01 44 185 "SLC12A5,CFLAR,KRIT1,LRRFIP1,LHX2,SLC4A8,SMARCAL1,JAKMIP2,ZBTB24,RHOBTB1,SACS,ANKRD46,RBM12,IRAK4,ARMCX1,TBC1D16,ZNF589,CNTRL,RNFT2,BRINP3,DIPK1A,ITPKB,JAK2,THYN1,PDCD2,PDE3B,PIK3R1,NLE1,POLG,ZSCAN32,ROBO1,MAP6D1,PAAF1,TMCC1,SPATA7,CEP68,KANK1,ZC3H4,FAM208A,ZMYND8,ZNF23,HPS4,NAV2,ZNF248" Drug CID005311262 LY393675 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRM1,GRM2,GRM5,GRM8" Drug ctd:C106263 rostafuroxin CTD 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ADD1,ADD3,LSS,ABCB1" Drug CID000008408 N2-M Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "APP,FGF1,GPM6A,TNIK" Drug CID003005587 thioformamide Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ABCC9,F3,PMP2,ABCC8" Drug CID000023941 H2PO Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ABHD6,GFER,GSN,NBL1" Drug CID002061047 DMeOB Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRM1,GRM2,GRM5,GRM8" Drug CID000014485 S-acetylthioacetic acid Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,PTPN5,HP,HPR" Drug CID000656707 LY395153 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000077338 fenclorim Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "KYAT1,GCK,GLUL,GSTCD" Drug CID005311425 SB 234551 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000643455 N-Boc-pyrrolidine Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "BOC,GCK,POLL,PMP2" Drug CID000001370 1-BCP Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID005328773 tyrphostin B52 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRM1,GRM2,GRM5,GRM8" Drug CID000197714 D-22888 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ALDH7A1,PDE4A,PDE4B,PDE4D" Drug CID000012075 "2,5-DNT" Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "DDO,RDX,TNNT1,NLRP3" Drug CID000197302 Be 18257a Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID003038472 irampanel Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID005231402 dihydroquinoline Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "NR3C1,PTPN5,HP,HPR" Drug CID000441873 thevetin A Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Drug CID000065740 Chicago acid Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000025781 monoethylcholine Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ACHE,BCHE,CACNA2D1,UBC" Drug CID000158474 enoximone sulfoxide Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ALDH7A1,CACNA2D1,PDE3A,PDE3B" Drug CID000145927 eudistomin M Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "TPM1,TPM2,TPM3,TPM4" Drug CID000129432 Et-(16-21) Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID003048146 d 245 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GFAP,PMS2,RNASE1,GSTCD" Drug CID000151819 diHPA Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "MED12,BRD8,MYH6,THRA" Drug CID000124528 pBB-PzDA Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIK1,GRIK3,GRIK4,GRIK5" Drug CID000063114 AC1L1YEG Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000094298 cryptocyanin Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ACHE,B3GAT1,NEURL4,TMEM132D" Drug CID011366019 CHEBI:40435 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "RNASE1,RNH1,S100B,CRB1" Drug CID004574540 L015040 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000016052 Ho-14 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "NTM,NUMA1,CLDN11,SOX10" Drug CID000132991 pd 151242 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000002184 dihomo-gamma-linolenylethanolamide Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "CNR1,EDN1,PTK2B,TTC7A" Drug DB05266 Ibudilast Drug Bank 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "PDE3A,PDE4A,PDE4B,PDE4D" Drug ctd:C472365 "3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine" CTD 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA2,GRM5,PTPN5,PDYN" Drug DB01198 Zopiclone Drug Bank 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABRA1,GABRA2,GABRA3,GABRA5" Drug CID000469585 CBVMP Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "AMPD2,AMPD3,POLG,TK2" Drug CID000093191 acetylcholine mustard Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ACHE,BSN,CHM,CHRM1" Drug DB00402 Eszopiclone Drug Bank 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABRA1,GABRA2,GABRA3,GABRA5" Drug CID000129091 5-h PCA Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID011334126 CHEBI:570577 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID006439238 amphidinolide D Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "TPM1,TPM2,TPM3,TPM4" Drug CID005311274 MEN 10627 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "B3GAT1,TAC1,TAC3,TACR1" Drug CID000009209 "1,7-naphthyridine" Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EGFR,PDE4A,PDE4B,PDE4D" Drug CID005311275 Men11420 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "B3GAT1,TAC1,TAC3,TACR1" Drug ctd:C037476 tert-butylbicyclophosphorothionate CTD 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABRA1,GABRA2,GABRB3,GABRG2" Drug ctd:D002724 Chlorobutanol CTD 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABBR1,GABRA2,GABRB1,KCNH2" Drug ctd:C006477 alphaxalone CTD 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABRA1,GABRA2,GABRB3,GABRG2" Drug CID000257501 2-phenylethenesulfonamide Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000007666 phenethyl bromide Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ACHE,BCHE,SOCS5,SMC2" Drug CID006918580 aclatonium napadisilate Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ABHD6,CCKBR,CHRM1,SST" Drug CID000147513 2-isopropylpentanoic acid Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "MAP2,NCAM1,NEFM,NEFH" Drug DB01346 Quinidine barbiturate Drug Bank 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GABRA1,GABRA2,GRIA2,KCNK1" Drug CID000107978 beta-N-oxalylaminoalanine Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000065882 ipenoxazone Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "GRIK1,GRIK3,GRIK4,GRIK5" Drug CID000055056 o-(N-phthalimido)acetophenone Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ACLY,CD320,DLL3,NETO1" Drug CID003082282 3-acetylstrophanthin Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Drug CID000195392 "22,23-dihydrobufalin" Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Drug CID003081320 Rim-1 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 4 5 "BSN,SNCB,SYN2,SYP" Drug CID000040032 Cloethocarb Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 15 45 "PRX,CBS,CDR1,TIGD7,CST3,FER,GFAP,GLRB,POLL,CLASRP,KCNA2,RET,TPM1,DPYSL5,EPM2A" Drug CID000091475 THDOC Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 15 45 "AGT,CALM1,CBR1,DBI,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,NR3C1,NPY,S100B,SCG2,SLC17A6" Drug CID000004539 norfloxacin Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 15 45 "SUMF2,PLCXD3,ENO2,STX2,ZMYND10,USP21,INSM2,PLCD4,MSRA,PLCB2,PLCD1,STX1A,PLCB1,NPL,ST8SIA2" Drug CID005464109 I06-1821 Stitch 2.69E-03 1.00E+00 1.60E-02 1.82E-01 15 45 "AGT,CNR1,GAL3ST1,CYBB,GHR,IGF1,IGFBP1,NPY,NPTX2,OXTR,SCG5,SST,SSTR1,TRH,VGF" Drug ctd:C011559 tributyltin CTD 2.80E-03 1.00E+00 1.67E-02 1.90E-01 96 466 "TTYH1,ACADM,ACTN1,ADRB2,AGT,UPRT,LRRC4C,ASPA,ATP2A2,CDK5R1,DST,CALM1,CAMK2B,CAMK2D,CAMK2G,CCKBR,CRLF1,JAM2,MAP4K4,LETMD1,GDA,ABCG1,CYBB,DBI,ZEB2,GSDME,SV2B,FAM78B,ABCC9,EGR3,NRN1,EFEMP1,FECH,FGF11,PCYOX1,SORBS1,DKK3,CHL1,GBX2,GFAP,GK,CCDC184,GRIA1,GRIA2,GRIA4,GRIN1,NR3C1,PTGDR2,ARHGAP36,HSD17B1,IDH3A,IGF1,ITGAM,KCNH1,KCNK3,L1CAM,MAPT,JAKMIP3,NDUFA5,NEFH,NF1,NFE2L2,NODAL,NOS1,NRDC,OGDH,PC,PFKFB4,ABCB1,PLIN1,PPARA,PRKCB,MAPK3,MAPK8,PTPRB,PTX3,SLC25A36,TMEM206,RIMKLA,RXRA,RXRG,MAPK12,SCP2,SOX6,KDM4B,SOX5,KDM3A,ZNF423,SYT4,TMEM178B,TF,LEFTY2,TJP1,TMOD1,TRH,CA14" Drug CID000091773 tebufenozide Stitch 2.81E-03 1.00E+00 1.67E-02 1.90E-01 9 21 "BTK,USP2,NCOR2,IP6K2,DDX19B,PDCD2,RXRA,TMEM132D,USP1" Drug CID000123659 bicuculline methochloride Stitch 2.81E-03 1.00E+00 1.67E-02 1.90E-01 9 21 "ABAT,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HRH3,SLC6A1" Drug CID000014829 Cu-O Stitch 2.81E-03 1.00E+00 1.67E-02 1.90E-01 9 21 "CDO1,CP,CDON,DNER,PKN2,LAMA1,FBXW7,SYN2,TMEM121" Drug CID000003895 lavendustin B Stitch 2.81E-03 1.00E+00 1.67E-02 1.90E-01 9 21 "CALM1,CAMK2B,CAMK2D,KCNMB4,KCNMA1,MATK,NTRK2,NTRK3,SLA" Drug CID000004158 methylphenidate Stitch 2.82E-03 1.00E+00 1.68E-02 1.91E-01 29 110 "BRAP,ATP2A2,CDK5R1,KIAA0319,DRD1,PPP1R1B,FGF14,SCARA3,FOXG1,AFF2,GRIA1,HNRNPK,KCNMA1,KITLG,NF1,NOVA2,OMG,ENPP2,SCN8A,SNAP25,BEX1,SST,MLST8,ARHGAP9,THRA,TRH,MFF,RTN4,FXR1" Drug CID000043234 propiconazole Stitch 2.87E-03 1.00E+00 1.70E-02 1.94E-01 14 41 "LARGE1,EFS,CLASRP,FICD,KIF2A,FSD1,ROM1,CLIP1,MRAS,CLASP2,TBL1X,CLASP1,TMEM121,CLIP2" Drug CID011708451 2 IMA Stitch 2.87E-03 1.00E+00 1.70E-02 1.94E-01 14 41 "APLP1,STX2,GABRG2,NCAM1,NOVA2,PLEC,PKIA,ELOVL2,PTPRN,SCN2A,SCN2B,STX1A,GORASP1,ST8SIA2" Drug CID004470173 AC1NBM3D Stitch 2.87E-03 1.00E+00 1.70E-02 1.94E-01 14 41 "ADORA2A,CCKBR,CNR1,CST3,BOC,PNMA2,KCNH2,MID1,P2RX7,PTCH1,SSTR1,SSTR2,TUBA1A,HPS4" Drug CID000023934 neodymium Stitch 2.87E-03 1.00E+00 1.70E-02 1.94E-01 30 115 "SERPINA3,ACHE,FZD9,APOC1,BCHE,NGB,RUNX1T1,CHN1,CHRM1,CHRNB2,CLU,CNR1,COX4I1,ACBD5,BLOC1S6,DLX1,CASP8AP2,AASS,POLK,INPP5K,HBA1,MAOB,MAPT,NBL1,NDP,NDUFS7,SNCA,PDZRN3,SYP,TP53BP2" Drug CID000010413 hydroxybutyrate Stitch 2.87E-03 1.00E+00 1.70E-02 1.94E-01 30 115 "ABAT,NGB,NRXN2,SLC32A1,ACOT8,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLUL,GRIN2C,GRIN2D,HBA1,MOBP,PENK,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,SCN2A,ADHFE1,MLST8" Drug CID000005143 saccharin Stitch 2.88E-03 1.00E+00 1.70E-02 1.94E-01 17 54 "ADCY2,ADCY5,ADCY6,ADCY8,CCK,NRXN3,SULT4A1,DBI,CHRDL1,DRD1,TCERG1,HTR2A,MTR,OPRL1,PLCB2,ARC,TRH" Drug 414_UP "estradiol, USP; Up 200; 0.01uM; ssMCF7; HG-U133A" Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "APOC1,ARRB1,ALDH4A1,ATP1A2,MTMR3,RUNX1T1,DLGAP1,CHRNA4,IFFO1,SH2B1,AATK,DTNA,ABCC9,SUGP2,PLEKHO1,NRN1,OLFM1,STAU2,GNAO1,BTN2A1,ADAMTS6,HMX1,ICA1,IL6R,MARK1,MYL3,MYO7A,NPR2,OPRL1,CCSER2,POLG,CEP41,PRKCB,RET,RLBP1,TMEM206,SLC9A5,KBTBD4,CDK5RAP2,KDM4B,ZBTB43,TF,ZNF34,CDH22,ZNF184,ST7" Drug 2991_DN Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "MTUS1,PLA2G6,ANK3,PDXK,ATP2B2,CADM3,BACH1,CACNB4,ARHGAP33,SOCS6,CLCN4,DNAJB5,OSBPL3,SLITRK5,ZNF337,TOM1,SEZ6L2,AASS,PIPOX,ZNF589,SEPT9,WASF3,LILRA2,GRK4,GRM7,KCND3,MGAT3,MOBP,ODF2,MAPK8,PTCH1,RAD52,RALGDS,RGS10,CLIP1,SLC1A7,WDTC1,EXOC7,TCF7L2,TNS2,TPM1,CDK20,MAP3K12,SEMA3B,PCBP4,JPH3" Drug 5228_DN 15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABAT,AP2A2,FAM131A,PPFIA3,ARRB1,ARHGEF7,CACNA1I,RCBTB2,SLIT2,RAB26,PPP6R2,DCAF8,MFAP3L,DLG3,MED12,DTNA,SIDT2,ZNF589,FGFR1,FGFR3,PRELID3A,GPR153,MSL3,GPR19,HNMT,MAN2A2,MMP16,NCAM2,NPTX1,PDE3B,PTN,RAB3A,RET,ASAP3,FUZ,SHANK2,SLC15A2,SNCA,LHPP,THSD1,FCHO1,CEP68,MCF2L,TMEM121,GDPD5,SEMA3B" Drug 4682_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ASPHD1,ADCY6,CDK10,PRX,CDK13,BMP7,CBS,ARHGEF1,ADGRG1,EPS15L1,TPP1,COL9A3,IFFO1,CRY2,ZNF391,GAB1,ZMYND11,ERAP1,TDRKH,GPR22,SPACA9,GRM7,ATXN2L,IL6ST,JAK2,KCNF1,LAMA2,ADAM11,NF1,PDE2A,MINDY2,PRPH,PLPPR1,RAD51D,ENOX1,ZNF821,RASA3,DOCK10,PREX2,SLC15A2,SNAP25,ATP10B,SZT2,DAAM2,VAV2,NSD2" Drug 4148_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADRA1D,SEMA4G,CDK13,RIPK1,CA4,B4GALT6,DCAF4,DAPK3,RCAN1,DTNA,HIPK3,SCML2,ZNF589,FGFR1,SEPT9,POLL,GNG3,MAPT,MDM4,NF1,NFYA,CNOT4,NUMA1,SETD4,CDK18,PLCD1,MINDY2,PRKAR1B,WDR25,PTN,RAB3IL1,RAB5B,TCP11L1,SH3BP2,SLC9A5,CXXC4,COA1,PDZRN3,PLCB1,ROBO3,SZT2,TMOD1,PARD3,TRPM2,EMSY,SCG2" Drug 1837_UP Chloramphenicol [56-75-7]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NDRG2,FAM135A,AMT,CDC42BPA,ARNTL,MARK4,SLC4A4,BACH1,HIP1R,LARGE1,ARMC8,KIAA0753,EFNB3,PLXNC1,GFER,COPS8,GNAO1,GNG4,IL6R,IL6ST,KCNQ3,KIT,MAP4,GIT1,N6AMT1,KCNK10,PIK3R1,RIPOR1,ARHGEF10L,EXD2,FERMT1,SLC1A7,SLC2A5,LIMS2,ZNF430,MAPKBP1,SNCA,DOK5,FCHO1,KIAA1107,TCF4,ATP13A2,NPDC1,ZNF74,REEP1,ST7" Drug 2367_DN Vincamine [1617-90-9]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,APP,CASK,NCOA1,SLC4A4,BCL2L2,BCL7A,SCAPER,CA12,CAST,SOCS6,EPS15L1,STOML1,FADS2,BAG4,NCOR1,MAML1,SGSM2,DNM2,DPH1,DTNA,ABI2,LRRC23,FHL1,OGA,GPR22,CNOT4,SETD4,RC3H2,MAPK8,GON4L,PTN,ZSCAN32,ZDHHC14,GSTCD,GALNT10,DOCK10,SLC15A2,MAPKBP1,NSFL1C,PJA1,DICER1,KAT6B,FLRT2,VIPR2,LAT2" Drug 2080_UP Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "RALGAPA1,KIDINS220,ANK3,GAS7,ADAM15,CFLAR,SCAPER,CLCN3,DNAJB5,HOMER3,ABI3BP,CHD1L,CREM,MFAP3L,SGSM2,ST8SIA3,EFNA3,MRNIP,ETV1,SEPT9,DBF4,GLRB,GPR17,STON1,BACH2,DHX35,JAK2,KIFC3,LIG4,CNOT4,RETREG1,SH3TC2,GAL3ST4,SLC6A8,ARFGAP1,SNCA,FNBP1,SS18,ATP11A,PSD3,ARHGEF12,AHCYL2,TRPC1,NSD2,STMN4,HPS4" Drug 1856_UP Nifedipine [21829-25-4]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ACTN1,PLA2G6,ALAD,AMT,APOC1,PDXK,N4BP2L1,KIF1A,SCAPER,SPAG9,CDO1,RAB33A,SLC4A7,CTNND1,GIT2,C2CD2L,SORBS3,ING4,MRNIP,DMTN,DLC1,CAP2,EFCAB2,KCNQ3,MARK3,SLC11A2,OLR1,MINDY2,PTPA,CNTLN,PTCH1,BSDC1,TCP11L1,PAQR6,SUPT20H,SH3BP2,WDTC1,TSPYL2,RGL1,SYN2,SIN3B,TNS2,CRTC1,ATP13A2,UBTF,ZNF74" Drug 364_DN trichostatin A; Down 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ACTN1,AK2,AMT,APBB2,APC,APP,CA12,CHRNB2,TAOK2,SLIT2,HOMER3,GIT2,DBN1,KLHL3,EFNB3,FAM13A,PCOLCE2,TUBB4A,FGFR1,FAM49B,STAU2,MPP6,GAD2,B4GALNT1,ALDH1L1,LYVE1,TXNL4A,PTPRT,MAN1B1,NEFH,NELL2,NPPA,DDR2,OCRL,PACSIN1,TNPO2,MAPK3,SYNDIG1,RPH3A,PPP4R3A,CEP68,PHLDB1,PRRC2C,SEMA4A,SMUG1,MPPE1" Drug 5680_DN Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "EPB41L5,APOC1,NCOA1,EIF4G3,BTRC,QKI,AKAP7,BAG4,SIPA1L1,PDE4DIP,FAM169A,DCAF8,MFAP3L,SMG7,MED12,DTNA,MRNIP,GART,TXNL4A,POLL,CNTRL,NR3C1,KCNJ3,MMP16,ADAM22,PTCH1,PEX5,RAD51D,ZCWPW1,RGS3,RGS10,RPS6KA2,SEC14L1,PPP4R3A,FAM214B,SLC22A4,ZHX3,SPTAN1,DIP2A,TCF7,ATP13A2,SLC44A1,MICAL1,NDRG4,EVI5,PDSS2" Drug 2426_UP Progesterone [57-83-0]; Up 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADD2,ANK2,APBA2,KIF1A,MPDZ,CACNA1I,CLDN10,SLC16A4,NEURL1,CDC27,EPS15L1,CREM,ABCG1,CSF1,DZIP3,DOCK4,DLG3,DTNB,FCF1,SORBS3,EIF1,MTSS1L,PTK2B,GPR153,ADAM28,PCLO,GRM7,GSN,KCNQ3,SCAMP5,NF1,PURG,PLPPR1,RGS12,SEMA6D,FRMPD1,RPH3A,SLC11A1,MAPK8IP3,DIP2A,ARHGEF9,DNMBP,TJP1,ZMYND8,VAV2,VGF" Drug 1654_UP clozapine; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADGRF5,BEGAIN,CDC42BPA,SEMA4G,MARK4,BTRC,KRIT1,RAB28,NMT2,PHF14,EDRF1,NR1D2,TSPAN5,PLEKHA1,VPS26C,F3,TRMO,DISC1,MSL3,GPD2,TDRKH,GPER1,MEIS2,ZNF862,NEK1,PDE3B,PDPK1,STRN3,RAB3IL1,RAD52,ASAP3,FNDC3A,ZCCHC24,HECW1,TTBK2,VPS13A,EXOC7,TBCEL,TIAM1,TK2,KAT6B,TRIO,VAV2,VGF,VLDLR,KAT6A" Drug 5574_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "PLA2G6,C1QTNF3,CDK10,SGCE,CAMK2G,KRIT1,CRLF1,QKI,HOMER3,AKAP7,CREM,SDC3,CTNND2,PPP6R2,TBC1D5,CNNM1,APH1A,RRAGB,EFEMP1,FOXG1,POLL,RASSF8,ICA1,RBPJ,KCNH2,VWA5A,TM6SF1,NACA,NOS1,STRN3,TMEM104,GTDC1,GSTCD,ROBO1,NEK11,FERMT1,FBXO11,BTBD7,USP33,ZCCHC24,ZBTB43,TBCEL,CRTC1,DICER1,ZIC1,SEMA3B" Drug 3204_DN Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "APC,FAM131A,CDK10,KIF1A,SCAPER,CAMK2G,USP2,QKI,HOMER3,WHRN,SH2B1,CTNND2,DBT,DTNA,EDNRA,COQ7,STX2,INPP5K,GLS,AGFG1,KHK,KITLG,MMP16,ADAM22,NF1,SLC25A23,APTX,ELOVL2,RAB3IL1,RALGDS,RGS12,RNASEL,NLGN1,ZNF365,WDTC1,EXOC7,AHCYL2,ZNF34,TK2,TMOD1,NPL,HIRA,VGF,VIPR2,SYNC,UBE3B" Drug 7181_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,BIN1,KIF1A,SCAPER,FOXN3,CLOCK,CSNK1E,DCTN1,SGSM2,DMPK,MED12,MAMLD1,SEZ6L2,RBM12,ERBB2,GABRA2,GPD2,ARHGAP19,AGBL5,MAN2A2,NF1,PLEC,MBOAT7,PRKAR1B,AMBRA1,ABLIM3,URGCP,SMTN,PDZRN3,SOX3,SPATA7,ZHX3,FCHO1,CEP68,ARHGEF9,PDLIM2,TNS2,KAT6B,CABIN1,TRPC1,TSC2,RPRM,LMF1,PHTF2,NUP214,ACTR3B" Drug 3539_UP (-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABR,NDRG2,TRMT9B,BIN1,CDC42BPA,PRX,ARRB2,CFLAR,MTMR3,GYG2,ARHGEF2,PLEKHB1,STOML1,PDE4DIP,SDC3,SV2A,CDON,DTNA,EPB41L1,EFS,FGFR1,INPP5K,GLYR1,GSTM5,GUCY1A2,KPNA5,LSS,PACRG,MDM4,NF1,PLEC,ELOVL2,GTDC1,TTLL7,ASIC4,ABLIM3,SLA,KANSL3,PKNOX2,KDM4D,SMARCD3,MAPK8IP3,AJAP1,TNS2,HEY2,SYNC" Drug 4663_DN Clioquinol [130-26-7]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ALAD,AMT,TAOK2,ABCG2,NRG2,NCOR2,ARHGEF10,VCAN,CNTNAP2,SDC3,ARHGEF4,DCAF4,PLXNC1,ING4,ERCC2,FGFR1,ANKFY1,GLYR1,GLRB,MSL3,POLL,CNTRL,DIDO1,LIG4,ADAM22,FSD1,SH3TC2,ARHGEF10L,MAP6D1,SCN8A,ZNF821,ST6GAL1,TMCC1,KDM4B,CAND2,RBM26,IQCE,TCF4,THRA,BHLHB9,TPM2,UBTF,TFIP11,EMSY,CIAPIN1,PHTF2" Drug 1158_UP chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AGT,MRTFA,PPP4R4,ARNTL,ATP1A2,SCARB1,NEURL1,REPS2,ZMYM4,IQCK,ABI3BP,CREM,DZIP3,PPP1R16B,EDRF1,ARHGAP32,DAPK1,DBT,SGSM2,HIPK3,EIF1,TUBD1,ST3GAL6,CAP2,CINP,GPR153,GABRA4,INPP5K,GRIK5,KCNJ5,OPCML,ST8SIA5,PPP5C,SIDT1,RGS3,SH3BP2,AMBRA1,BTBD7,KDM4C,STX1A,DMXL2,TCF7L2,TNS1,RBFOX2,FLRT2,REEP1" Drug 3524_DN Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "KIDINS220,AP2A2,BCAS1,CDK10,CAPRIN2,ATM,CFLAR,BTRC,CFAP410,CAMK2G,SOCS6,B4GALT6,QKI,PDE4DIP,RIMS3,GIT2,DBT,RUSC2,KBTBD11,DTNA,EGFR,FHL1,SRCAP,MSL3,CNTRL,HNMT,PCDH9,PRPH,RALGDS,WLS,KIF13A,EMC1,SPTAN1,CEP68,PHLDB1,STX1A,AJAP1,POPDC3,EXOC7,ZNF34,ZMYND8,KLC2,REEP1,MAP3K12,MPPE1,C12orf4" Drug 6766_DN Dipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,FAM131A,PPFIA3,PLA2G4C,CDK13,KIF1A,PTBP2,MAGI1,SLIT2,RAB28,AKAP12,DZIP3,CTNND2,EDRF1,GIT2,MFAP3L,SGSM2,DTNA,EDNRA,SORBS3,FGFR1,ATP2C1,CGREF1,INPP5K,GLS,KHK,LIG4,NNAT,CNOT4,NUCB1,SERPINE2,SMIM7,ROM1,UEVLD,TRAPPC13,SBF1,SMARCC2,ARHGAP26,PHLDB1,KAZN,KAT6B,HIRA,LMF1,PRDM2,ACTR3B,SSPN" Drug 4997_DN "Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NME5,SRPX,PPFIA3,APP,ADAM15,CFLAR,ADGRG1,PLEKHB1,DOCK4,RIMS3,GIT2,MFAP3L,DNM1,EFNA3,ABI2,ING4,USPL1,ANKMY1,ZNF589,FER,BAIAP2,PDLIM5,DISC1,GPD2,RASSF8,INPP5B,ZNF862,NUMA1,SLC25A23,APTX,PTHLH,RAB3A,CCDC25,ZNF821,SMTN,BTBD7,KDM4C,ANKRD28,EXOC7,IQCE,CRTC1,TRPS1,PLPPR2,KLC2,REEP1,GDPD5" Drug 2210_DN Mefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ASIC1,SEMA6A,PDXK,ATP6V0A1,CA4,HAP1,CAMK2G,SLIT2,DNAJB5,PICK1,RIMS2,SH3GLB1,SORBS3,COQ7,PDLIM5,FAM49B,CGREF1,MALT1,GSTM5,KCNF1,KCNH2,KCNN2,MAP4,MMP16,MYO7A,OPA1,PLEC,MAPKAP1,RAB3IL1,ATG16L1,RGS10,GSTCD,ROM1,TCP11L1,MAP6D1,KIF13A,CLASP2,CEP68,PLCB1,ROBO3,KIAA0930,PSD3,ARHGEF12,METTL3,HIRA,SYNC" Drug 1744_UP Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NDRG2,ADD2,PLA2G6,C1QTNF3,CNTNAP1,APBB2,APP,ARHGEF1,TM9SF4,GIT2,TRAPPC9,FAM13A,SORBS3,RASGRP2,IGSF6,KAT8,CAMSAP1,SEPT9,ALDH1L1,RUNDC3A,PRRC2B,NXPH3,HRH3,HMX1,KCNJ3,MYT1,PAK3,PALM,CCSER2,NLE1,PACSIN1,DEF8,GON4L,FAM102A,AMBRA1,URGCP,MAPKBP1,KIF21B,SYT1,TK2,PARD3,RBFOX2,NPDC1,ZNF142,MPPE1,SMIM8" Drug 2099_DN Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "BRAP,APC,SHROOM2,MARK4,NUMB,FOXN3,KIAA1549L,HOMER3,HP1BP3,DMTF1,EDN1,EDNRA,MPP6,SEPT9,COPS8,PRRC2B,BTN2A1,INPP5B,ITPKB,KIF2A,MX1,NUCB1,PDE1C,PFKFB2,NLE1,ZNF426,GTDC1,MCMBP,SH3BGR,PEX26,FAM214B,KDM4D,KBTBD4,SLC20A2,ARHGEF9,SYT1,TCF4,NSD1,ARHGEF12,FRYL,UBTF,UPF3A,VPS35L,WIPF2,FZD3,AAAS" Drug 2719_DN Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADRA1D,KIDINS220,SRPX,CDC42BPA,APOC1,PPP4R4,NUMB,LDLRAD4,CACNA1A,EPS15L1,AKAP7,CSNK1G3,USP6NL,SMG7,DTNA,EFNB3,SUGP2,IGSF6,F5,ST3GAL6,PCYOX1,IQCG,ZNF44,ZMYND11,ERAP1,SEPT9,GPR75,GNG4,IL6ST,MAP4,NPR2,PCDH9,PENK,POU6F1,PTK2,PEX5,SEC14L1,SLC11A1,MAPK8IP3,FAM168A,ADGRL3,KIAA1107,TCF7,TCF7L2,PLPPR2,CLIP2" Drug 3992_DN Phenacetin [62-44-2]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ANK3,APC,APP,MARK4,SLC4A4,SLC25A14,SEPT7,FOXN3,SLC4A8,CREM,AATK,TENM4,SLITRK5,DZIP3,PPP6R2,DCAF4,ZNF337,DLG3,MFSD10,COQ7,STX2,ZNF589,FGF1,B4GALNT1,IL11RA,MIA2,MN1,PPARA,GRAMD1C,SH3TC2,MSANTD2,FBXW7,PAQR6,RXRA,IL17RB,FBXO11,ST6GAL1,FAM214B,ARHGEF40,RBM34,ZBTB43,MAPK8IP3,ARC,SSBP2,HPS4,NAV3" Drug 1681_UP Epirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADD3,GAS7,APLP1,APP,RGS20,SLC4A4,STX16,LDLRAD4,CA4,CBFA2T2,RAB28,RASSF2,ATN1,ING4,DMTN,ANKMY1,F3,FOXG1,ERAP1,ALDH1L1,GLYR1,GNG4,PTGDR2,KCNMA1,MAN2A2,MAP4,NF1,NFYA,CNOT4,PCDH9,PRKAR1B,MAPK8,RFX2,RGS10,BCAN,ZCCHC24,TROVE2,SYN2,TCF7L2,GPR161,TNS1,RBFOX2,VLDLR,XRCC4,GDPD5,PLSCR4" Drug 7371_UP Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ACTN2,AMPD3,CADM3,SYNJ1,BAIAP3,CAMK2B,CDH10,ADGRG1,NRXN3,PICK1,PCYT1B,CREB5,EDNRA,CNNM1,EIF4G2,EFS,ANKMY1,AGAP2,SEMA4D,GRM1,IRAK3,TJAP1,MAPT,MGAT3,MMP16,GON4L,PTPRH,KLHDC8A,EMID1,MRAS,FRMPD1,PKNOX2,ZNF667,MYH15,ZSWIM8,KDM4C,UNC5B,ARHGAP26,INKA2,VAMP1,GPR161,TNS1,LAT2,SCG2,KCNAB1,NUP214" Drug 7226_DN Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "CDC42BPA,BCAS1,PPFIA3,MPDZ,C5,CBFA2T2,QKI,CREM,CSNK1E,GIT2,DCTN1,EDNRA,EIF5,F3,TESK2,FOXG1,PRRC2B,GRB10,IPO5,MAP4,RETREG1,TNPO2,RIPOR1,GTDC1,ARHGEF10L,RNASEL,TCP11L1,FOXRED2,SBF1,FUZ,AMBRA1,FNDC3A,ABLIM3,SMTN,CAMTA2,ELOVL4,FAM168A,KAZN,EXOC7,TCF7L2,AHCYL2,TIAM1,BEX4,ZNF24,SCG2,HPS4" Drug 6445_DN Meglumine [6284-40-8]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AK2,SEMA6A,AMPD3,EPB41L5,RIPK1,ADAM15,BAIAP3,LDLRAD4,CA12,CNOT8,ZFYVE9,NECTIN3,PDE4DIP,GREB1,ATN1,EFNB3,STX2,F3,TXNL4A,CRCP,KCNJ3,VWA5A,MAP4,MAPT,MGAT3,MMP16,RC3H2,RAB3A,KHDRBS2,FUZ,BCAN,SLC20A2,NXT2,CEP68,KANK1,TRIM2,THRA,CABIN1,SSBP2,HIRA,FAM155A,VAV1,SYNC,PRDM2,ST7,SSPN" Drug 7455_DN Panthenol (D) [81-13-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,MTUS1,AK2,APAF1,MARK4,ATP2A2,MTMR2,SCARB1,TAOK2,DZIP3,CTNND2,DCAF8,ZFYVE16,ZNF337,RIMS3,KIAA0586,GIT2,LYPD1,FEM1B,APH1A,SORBS3,EIF5,CINP,GPD2,NR3C1,AGBL5,KIF5C,LSS,NF1,OGG1,OXTR,GTDC1,ROBO1,ITSN1,FERMT1,FNDC3A,ZNF365,SLC15A2,KDM4B,WDTC1,SPART,TACC1,MCF2L,EXOC7,HIRA,NDRG4" Drug 7010_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AK2,ARRB1,MTMR9,CADM3,SCAPER,GYG2,BTRC,CBFA2T2,FOXN3,CTNND2,CYBB,DLG3,MED12,SLC12A6,ATN1,RCAN1,DTNA,PHF20L1,NRN1,FER,FAM49B,RAB40B,GRB10,NF1,CNOT4,RETREG1,PMP2,MAPK7,PTHLH,RAB3A,RPS6KA2,ASAP3,SLC6A8,ZCCHC24,ERC1,MAPK8IP3,AJAP1,TRIM2,DOCK9,CRTC1,RBFOX2,PLPPR2,ZNF45,EMSY,SEMA3B,ST7" Drug 3048_DN Propofol [2078-54-8]; Down 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "RALGAPA1,CDK13,MARK4,CACNB2,HIP1R,SLC16A4,CHRNA4,RAB33A,ZFYVE9,STOML1,SLC4A7,NRG2,VCAN,PDE4DIP,ZNF337,DBT,SMG7,DYRK1A,PLXNC1,SORBS3,MRNIP,KIAA1109,GCNT2,COPS8,ICA1,VWA5A,NPR2,PDE4A,PDE4D,SLC25A23,PPP3CC,RAD52,ZCWPW1,RGS3,NEK11,ZNF821,SH3BGR,SH3BP2,MAPKBP1,EMC1,TROVE2,KIAA1107,TCF4,THBS4,ZNF225,ST7" Drug 6029_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADORA1,EPB41L5,FAM131A,CDC14B,SCAPER,MTMR2,C5,CRLF1,SOCS6,TAOK2,RAB28,PLAA,VAX2,CNTFR,AKAP7,CSF1R,MICAL2,SIPA1L1,GREB1,RASSF2,RCAN1,EGFR,SORBS3,ZNF589,GPR153,GAB1,INPP5B,JAK2,KCNN2,MMP16,MPP2,ADAM22,NEK1,SETD4,LRP12,MBOAT7,MAPK7,WDR25,ZFHX4,GSTCD,SGK1,SEMA4A,PCDHA5,TK2,CABIN1,GAN" Drug 7200_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "MRTFA,CDC14B,BCL2L2,CDK5R1,MTMR2,VAX2,QKI,FEZ1,MICAL2,GIT2,LYPD1,RCAN1,EFNA3,MBNL2,DENND4A,CDKL3,CAMSAP1,SEMA4D,TRAF3IP2,COPS8,CACFD1,IL6ST,KCNMA1,LIG4,MSR1,SLC11A2,SETD4,STRN3,CNNM2,ZSCAN32,BSDC1,SH3BP2,KANSL3,RAB3GAP1,CLASP2,NXT2,TTBK2,JMJD6,PLCB1,SEMA4A,SMG6,AHCYL2,TPD52,CLDND1,KCNK12,SYNC" Drug 2312_DN Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADD1,MRTFA,SEMA7A,APBB2,FAM131A,APOC1,NCOA1,ATM,SLC4A4,RIPK1,CFLAR,CDK5R1,CRY2,EDRF1,DCAF8,HP1BP3,F3,DPYSL4,TXNL4A,COPS8,POLL,GSTM5,HNMT,ZNF862,CNOT4,SLC25A23,LRP12,MINDY2,RIPOR1,GTDC1,ITSN1,FNDC3A,SLC15A2,TTC17,TSPYL2,TROVE2,ANKRD12,TCF7L2,PCDHA6,TK2,ZKSCAN5,PLPPR2,VGF,ZBTB14,EPM2A,UBE3B" Drug 4826_DN "Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ADRA1D,AK2,LTBP4,MRTFA,PKP4,APOC1,CAPRIN2,RIPK1,ADAM15,AP4M1,FAM189A2,DCAF8,ZNF337,DCTN1,B3GAT3,DLG3,DNM2,ATN1,EFNA3,SUGP2,PRRC2B,BTN2A1,MAP4K5,HNMT,MAP4,MBD1,PLEC,MBOAT7,PTK2,ZDHHC14,RGS3,ATXN2,SH3BP2,ELMO2,SMARCA4,PHLDB1,TRIM2,ATP13A2,CBX5,UBTF,PLPPR2,VGF,NSD2,XRCC4,NDRG4,WNK1" Drug 7424_UP Prednisolone [50-24-8]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AK2,C1QTNF3,APBB2,ADAM23,CFLAR,ST3GAL5,SYNJ2,CACNG1,KYAT1,MAGI1,CHRNB2,FEZ1,GIT2,DPH1,HIPK3,EFNA3,EGR3,COQ7,AGAP2,DPYSL4,ERAP1,GLYR1,RNFT2,IL6ST,KPNA5,MBD1,CNOT4,PACSIN1,PPP5C,RIPOR1,RGS12,MAPK12,COA1,SNCA,TNIK,AJAP1,VAMP1,EXOC7,KIAA0930,WDR7,CRTC1,TMEM121,SEZ6L,WRN,MAP3K12,SSPN" Drug 5807_UP Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ARID1A,AGT,C1QTNF1,SYT13,ANK2,DNAH17,ATP1A2,CFLAR,CACNA2D1,ABCG2,HAPLN1,SLITRK5,GIT2,ARNT2,EDN3,EGFR,MBNL2,IRAK4,TNK2,ELN,RRAGB,SCML2,BAIAP2,CGREF1,GLS,SPACA9,GSTM5,ICA1,KIF2A,MAN2A2,MAPT,NTRK2,PC,ENPP2,PPP5C,FNDC3A,LIMS2,SLC11A1,IQSEC2,ARC,WWC1,TRIM2,TLR4,TPM1,ZMYND8,KCNAB1" Drug 2447_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,SYT13,ARRB1,GYG2,INA,CNTN1,PDE4DIP,EDRF1,MFAP3L,DSCAM,DTNB,E2F5,HEYL,EIF1,COQ7,ERBB2,DLC1,NSG1,GAB1,ZNF44,ICA1,KCNA2,MDFI,SCAMP5,AFF1,MSR1,KCNK10,PFKFB2,CAMKV,MTRF1L,PURG,WDR25,PSMD13,PTPRN2,FAM120C,PID1,SHANK2,SLCO1A2,ATP10B,SYT5,PCDHGA10,CRTC1,TPM3,ZMYND8,VAV2,PAK5" Drug 2010_UP Erythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ASIC1,ADORA1,CDC42BPA,NRP2,SCAPER,CACNA1I,CAPN3,ARHGAP33,C2CD2,SOCS5,TOM1,STX2,ATP2C1,INPP5K,DBF4,MSL3,PCSK1N,ITPKB,KCNJ5,LSS,MITF,NELL2,NPPA,NUMA1,PDE4D,PENK,SLC25A23,SMIM7,PPP2R2B,RLBP1,LGR4,ITSN1,ZC3H13,SPART,SRPK2,ZC4H2,TK2,SEZ6L,UBTF,TBC1D15,WRN,ZNF23,ZNF142,REEP1,NUP214,ACTR3B" Drug 4785_UP Idoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "PLA2G6,APBA2,ARNTL,BRINP2,CFAP410,SYNGR3,SEPT7,CNTFR,GIT2,SPOCK3,DSCAM,EFNA3,MTSS1L,PIPOX,KAT8,FYB1,SRCAP,GPD2,GPER1,ADAMTS13,GRM2,ICA1,ITGA7,KCNQ3,KHK,VWA5A,MPP2,SLC11A2,LRRN3,FAM184A,SELL,FRMPD1,CPEB3,ST6GAL1,SLC1A7,FAM214B,PKNOX2,ST5,GPR161,TGFBR3,TK2,BEX4,DNAJC12,FLRT2,REEP1,KCNAB1" Drug 3269_DN "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "KIDINS220,AP2A2,GAS7,FAM131A,APOC1,ATM,SLC4A4,MTMR2,CACNA2D2,FAM189A2,VAX2,QKI,SH2B1,CSF1R,EDRF1,EFNB3,SORBS3,IRAK4,FER,FHL1,OGA,SRCAP,FERMT2,TDRKH,SPACA9,GSN,HNMT,LIG4,MAP4,MPP2,ADAM22,LYRM9,SLC11A2,NRGN,NLE1,SLC25A23,PRKAR1B,RAD52,EMID1,WLS,TTC17,KDM4B,IQSEC2,TBL1X,TCF7L2,SSPN" Drug 4120_DN Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NDRG2,AMT,APBA2,ARHGEF7,SCAPER,BTRC,PLAA,HOMER3,AKAP12,HP1BP3,IRAK4,ZNF589,FGF13,GALC,GLYR1,GNAS,PCLO,INPP5B,KCND3,MATK,KITLG,ADAM22,ZNF862,NEK1,NF1,NFYA,NOS1,RETREG1,STRN3,PLPPR1,PTHLH,PTN,FAM184A,RGS12,SEMA6D,CPEB3,ABLIM3,SLC1A7,PPP4R3A,FAM214B,BTBD7,SNCA,SS18,AHCYL2,AP4E1,VIPR2" Drug 3095_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "MTUS1,AMPD3,BIN1,APBB2,ADAM23,NRP2,C5,MYRF,BTRC,CACNA1A,SCARB1,CLCN4,NMT2,DBT,SMG7,OPTN,VPS13B,ERCC2,RRAGB,KAT8,ZNF44,ALDH1L1,GPD2,NF1,NINJ2,NUMA1,OGG1,CDK14,PLTP,PRKAB2,ZSCAN32,BEND5,TCP11L1,KDM4B,EMC1,DBNDD2,NCDN,MAPK8IP3,ADGRL3,SYNE1,TGFBR3,TMOD1,ZKSCAN5,FLRT2,ZNF74,ST7" Drug 3850_DN Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AMH,APAF1,GAS7,CDK10,NCOA1,CDK5R1,SYNJ1,BAIAP3,TAOK2,CLU,ENTPD4,SDC3,DCAF4,DUSP9,SORBS3,ELN,SCML2,TPK1,SRCAP,GFER,PCDH17,PCLO,CACFD1,HNMT,ITPKB,NPPA,RETREG1,STRN3,MAPK7,SNRK,ZSCAN2,ZDHHC14,ZMAT4,RGS10,EMID1,SBF1,PPP1R9A,ZNF365,SLC1A7,FAM214B,SHANK2,DMXL2,KIAA0930,LAT2,EMSY,KCNAB1" Drug 390_DN retinoic acid; Down 200; 1uM; HL60; HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABAT,BRAP,ANK1,APOC1,CA12,CACNA1D,CAST,RUNX1T1,RGS6,MICAL2,DCAF8,NR1D2,SGK2,EFNB3,ERBB2,C1orf61,IQCG,FYN,GABRA4,NEU3,HPGDS,GNG4,PRRC2B,KCNN2,MAP4,NEFH,NELL2,DDR2,PRRX1,PPP2R2B,ACSM5,PYGM,RIPOR1,RAD51D,SUSD4,RLBP1,STUM,SMTN,KBTBD4,ZBTB43,SRPK2,KANK1,PLCB1,TBL1X,TPD52,TRIO" Drug 6786_DN Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABHD6,NME5,APC,ARHGDIG,ALDH7A1,BTRC,CACNA1D,ARHGAP33,SLIT2,EPS15L1,ZFYVE9,FAM189A2,PICK1,CRY2,ABCG1,PDE4DIP,SDC3,CTH,EDRF1,GIT2,DMTF1,HIPK3,ELAVL3,ANKMY1,GAD1,SYT17,GLS,KCNMB4,GPD2,MUM1,LYRM9,RETREG1,CCDC25,SBF1,BCAN,SHANK2,SLC15A2,EMC1,UHRF1BP1L,SS18,NXT2,CEP68,PLCB1,FBXW11,AHCYL2,EMSY" Drug 6396_UP F0447-0125; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "APP,CHRD,SOCS6,NRXN1,CREM,IPCEF1,SPOCK2,CTIF,EDIL3,EDN1,EDNRB,TENM1,VPS13B,MTSS1L,EFS,F5,PDLIM5,IRF8,IGFBP1,INPP5B,MOBP,P2RY13,PNMA3,MINDY2,ACSM5,MARCH1,ZNF493,TRIM68,TTLL7,FRMPD1,BCAN,SLC4A3,SLC12A4,SMARCD3,MYT1L,KIF21B,HECW1,UNC5B,SYP,POPDC3,OBSL1,TRH,UCHL1,OSBP2,ITM2C,AP3B2" Drug 2019_UP Edrophonium chloride [116-38-1]; Up 200; 19.8uM; HL60; HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ACLY,CDC42BPA,APP,CDK10,ST3GAL5,RUNX1T1,SEPT7,CLTB,AKAP7,CHD1L,ARHGEF10,SOCS5,HP1BP3,NR1D2,ERCC2,FGF1,ATP2C1,GALC,RUNDC3A,TXNL4A,PCSK1N,IRAK3,MAN1B1,MPP2,NTRK3,OCRL,PAK3,PDE1C,PACSIN1,SBF1,ZNF821,SH3BP2,PPP4R3A,ELMO2,BTBD7,RCOR3,SNAP25,EMC1,TCF7L2,THRA,TNS1,TSN,LAMP5,TFIP11,ST7,NUP214" Drug 2506_DN Estropipate [7280-37-7]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NDRG3,AMPD3,MARK4,SLC25A14,CAPN3,KRIT1,EPS15L1,HOMER3,BAG4,CSF1R,DBT,SPATA2,KIAA0753,ECSIT,F8,CAP2,CELF1,NUDT21,CACFD1,FICD,MAP4K5,IL6R,ITPKB,LSS,MAP4,MATK,NF1,NFYA,RETREG1,LRP12,TMEM231,C1orf54,GTDC1,AMBRA1,NUBPL,WDR37,SPATA7,NSFL1C,JMJD6,VPS13A,TCF4,TCF7L2,RBFOX2,UBTF,FLRT2,ZNF32" Drug 2098_UP Antimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ASIC1,AQP6,ADGRB2,NRP2,ARHGEF2,ARHGAP22,CPNE6,AKAP7,DBT,DYRK1A,RGS17,ZNF589,FGF1,SEMA4D,GAB1,SIGLEC8,NEU3,C1QL1,TDRKH,ADAMTS13,ELOVL5,KIF5C,MMP16,NEK1,NOS1,PDE2A,PDE4D,RAD52,RALGDS,SUGCT,SLC1A3,SLC4A3,SLCO1A2,TNIK,ZHX3,UNC5B,ZBTB43,LHPP,ELOVL4,SYNE1,DNAH7,TRO,LAT2,MAP3K12,SLC17A7,PLSCR4" Drug 1639_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ARID1A,LTBP4,MRTFA,CDK10,BCL2L2,CFLAR,CACNA1D,CREM,PDE4DIP,CTNND2,DCAF8,HDAC4,INTS1,GIT2,DBT,SMG7,PARD6A,EFNA3,ECSIT,IP6K2,HTATSF1,GOLGB1,BTN2A1,GIT1,MYO9A,OGDH,PDE3B,SLC25A23,PPP5C,PRKAR1B,MAPK3,TMEM231,RET,GTDC1,ARHGEF10L,FBXW7,PDZRN3,EMC1,LHPP,PBLD,MCF2L,EXOC7,RBFOX2,SH3GLB2,WNK1,ST7" Drug 5615_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AP2A2,NME5,ALCAM,AMT,FAM131A,NUMB,CFLAR,SGCE,ARHGEF2,REPS2,PLEKHB1,TPP1,NMT2,QKI,HOMER3,SIPA1L1,DOCK4,DSCAM,RRAGB,EZH1,FER,FGFR1,FOXG1,NCKAP1,MALT1,GLYR1,CACFD1,INPP1,INPP5B,KITLG,NPTX1,LRP12,PPP3CC,PPP5C,RAB3IL1,RGS10,NEK11,SYBU,SLC22A4,WDTC1,TROVE2,CLSTN2,TTBK2,PLCB1,SIK3,SLC17A7" Drug 3284_DN Hydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "PLA2G6,DOC2A,KCNAB2,APBB2,APOC1,CFLAR,BMP7,ARHGEF2,CLGN,CACNA2D2,ZFYVE9,QKI,ENTPD4,SH2B1,CTH,EDRF1,DAPK3,RCAN1,SORBS3,FGFR1,FAM49B,PRELID3A,ERAP1,COPS8,HNMT,INPP5B,KCNH2,KCNJ3,MAP4,NF1,SLC11A2,OGG1,RGS10,SPTAN1,VPS13A,SEMA4A,KIAA0930,TCF7,TCF7L2,BEX4,TSN,RPRM,VGF,SEMA3B,MPPE1,ST7" Drug 6042_UP Hippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "SYN3,PLA2G4C,MARK4,ALDH7A1,CACNA2D1,WHRN,NCOR2,CNTNAP2,RIMS3,RUSC2,SV2A,SRPK3,C3orf18,HSD17B14,VPS13B,EFS,GAD1,PCDH17,GNG3,GRM3,ITGA7,ITPKA,KIT,MAOB,MTRF1L,NECAB2,MINDY2,PPP2R2B,GRAMD1C,SAMD9,FAT4,RGS12,RPS6KA2,SYNDIG1,PKNOX2,SMARCD3,SOX10,ATP10B,AJAP1,TCF4,PCDHGA10,TLR4,HEY2,TPM2,AMACR,VAV2" Drug 6273_DN Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "CDC42BPA,DGKD,PDXK,ATM,BACH1,SCARB1,SRSF11,RAB28,PLAA,COL4A5,DBT,RABGAP1L,DLG3,PHF20L1,PCOLCE2,EZH1,PRKAG2,PDLIM5,INPP5K,NR3C1,RNFT2,HSF2,ICA1,MAP4,MBD1,LYRM9,NEK1,NFYA,OGG1,MED1,PPP3CC,PRKAB2,PEX5,WLS,FOXRED2,PDZRN3,TSPYL2,ELOVL4,NSFL1C,ANKRD12,MCF2L,DNMBP,TRIM2,XRCC4,MPPE1,PHTF2" Drug 5499_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "SERPINA3,SRPX,APP,RIPK1,KIF1A,BCL2L2,KYAT1,AP4M1,BAG4,CREM,PDE4DIP,MED24,ATN1,DSCAM,RCAN1,DTNA,SUGP2,COQ7,STX2,FHL1,TRMO,CINP,FAM49B,INPP5K,FERMT2,ICA1,KHK,NF1,NTRK2,CCSER2,SLC25A23,RGS10,FOXRED2,MAPKBP1,WDTC1,NXT2,PHLDB1,WWC1,ATP13A2,ZNF34,CABIN1,CDK20,NPL,XRCC4,KAT6A,SMIM8" Drug 1276_UP Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "PLA2G6,FAM131A,CDK10,SLC4A4,AP4M1,NMT2,VCAN,DBT,SMG7,RABGAP1L,FCF1,SUGP2,ABI2,PLXNC1,EIF5,COQ7,CDKL3,TUBB4A,TRAF3IP2,SEPT9,ADAM28,MSL3,CACFD1,JAK2,N6AMT1,NEFH,NNAT,PDE4B,NECAB2,MAPK3,RAB3IL1,RGS12,MYH14,ZNF671,SEC14L1,ZNF667,PALLD,TMCC1,WDTC1,KANK1,IQCE,ARHGEF12,LAMP5,HPS4,EPM2A,UBE3B" Drug 1054_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "NDRG3,MAP4K3,ATM,ATP2B1,MTMR3,MTMR2,CANX,HIP1R,LHX2,HOMER3,FEZ1,APPL1,DCAF8,ZNF337,DBT,MFAP3L,RHOBTB1,SGSM2,FEM1B,MBNL2,ENO2,EPB41L1,EFEMP1,MYO9A,TMEM231,ROBO1,PCMTD2,ITSN1,PPP4R3A,BTBD3,KBTBD4,TMCC1,USP33,ZBTB43,NCDN,DIP2A,FAM168A,COBL,PARD3,TRIO,UBE3A,XRCC4,MFF,FIP1L1,PHTF2,ACTR3B" Drug 4317_UP Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "LTBP4,AMPH,PPFIA4,APAF1,ADAM15,ADGRG1,CHRNB2,ARHGAP22,CLCN4,PDE4DIP,TOX,RIMS3,ABCC9,EFNA3,EGFR,ZNF549,NSG1,ERAP1,PCDH17,GLYR1,RAB30,GNAO1,GPM6B,SOX21,KIT,KITLG,MOBP,NPTX2,PCDH9,PFKFB3,PFKFB4,TNPO2,MAPK7,GDPD2,ZSCAN32,KHDRBS2,RGS4,SLC1A7,KANSL3,ELMO2,KDM3A,IQSEC2,NXT2,TACR1,VAV2,LAT2" Drug 5505_DN Chrysin [480-40-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "APBB2,APC,APOC1,SLC4A4,CDK5R1,SYNJ2,NMT2,AKAP7,IQCK,ARMC8,AKAP12,NCOR1,MICAL2,PDE4DIP,KIAA0586,EXOG,EML1,COQ7,PDLIM5,GAD1,DISC1,MALT1,PRRC2B,KIF2A,MAP4,MIA2,NFYA,CCSER2,PRKAR1B,PRPH,PTCH1,NKAIN1,RGS3,RGS10,TTC17,ZSWIM8,CDK19,IQCE,TCF7L2,CLASP1,SSBP2,HIRA,REEP1,ZNF189,SH3GLB2,EVI5" Drug 4473_DN Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "PLA2G6,MRTFA,DOC2A,CDK10,CASK,MARK4,ADGRB2,CFLAR,MYRF,BTRC,ARHGAP33,CLCN4,HAPLN1,ABCG1,VCAN,CNTNAP2,DBT,EFNA3,COQ7,FGF1,PDLIM5,FAM49B,SEPT9,GART,GLYR1,SHISAL1,KCNJ5,LSS,LYRM9,NDUFA5,PIK3R1,TNPO2,KLK6,PID1,GAL3ST4,MYH14,IL17RB,WDTC1,TROVE2,NXT2,ASTN2,SZT2,SLC44A1,TPM2,PHTF2,AAAS" Drug 3472_UP Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "AK2,C1QTNF3,APAF1,SEMA4G,RASL11B,ATM,SLC4A4,ATP2A2,CFLAR,CACNA1I,CAMK2G,ZFYVE9,SLC4A8,ENTPD4,GREB1,ARHGEF4,RUSC2,C2CD2L,GNE,VPS13B,VPS26C,FOXG1,SORBS1,GPR153,SEPT9,SRCAP,IL6ST,KCNH2,SETD4,RAB3IL1,SMARCD3,ZCCHC24,SPTAN1,CDK19,ZBTB43,POGZ,DIP2A,KAZN,EXOC7,ZEB1,ZMYND8,UBE3A,WIPF1,REEP1,WNK1,PCBP4" Drug 2373_DN Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABHD6,ADORA2A,C1QTNF3,ALK,MRTFA,DOC2A,ZBTB10,ATP2B1,LDLRAD4,CAST,CDH10,TAOK2,IQCK,ARMC8,CPS1,ARHGEF10,VCAN,TM9SF4,SGSM2,ZNF589,FYB1,GAD2,ERAP1,GRM1,LIG4,NEFH,CNOT4,OGG1,CDIP1,PPP3CC,MAPK8,TMEM104,RALGDS,TCP11L1,RASA3,AMBRA1,FNDC3A,RAB3GAP1,WDTC1,ZBTB43,DDN,ZC4H2,STXBP1,TCF7L2,AHCYL2,PHTF2" Drug 4467_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "LTBP4,APBB2,APC,CDK13,SLC4A4,SCAPER,CDC42,ADGRG1,CNTN1,TCEAL2,OSBPL3,VCAN,DPH1,CDKL3,FGFR1,EFCAB2,DPYSL4,CINP,HBS1L,ZNF276,GRIK5,PADI2,ICA1,SHISAL1,VWA5A,MAPT,MDM4,KITLG,MMP16,NF1,ODF2,POU3F2,PRKAR1B,MAPK7,RAB3IL1,SPTB,DDN,KAZN,WWC1,EHBP1,TNS1,RPRM,XRCC4,SCG2,SEMA3B,KAT6A" Drug 7408_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.88E-03 1.00E+00 1.70E-02 1.94E-01 46 196 "ABHD6,ADCY6,APBB2,PPFIA3,MPDZ,ARHGEF7,SCAPER,CA4,SOCS6,LRIG1,FAM169A,DZIP3,CTNND2,MFAP3L,PHF20L1,EGFR,EGR3,COQ7,F3,F8,TESK2,GRB10,INPP5B,KCNJ3,MATK,MBD1,ADAM22,CNOT4,PLTP,MBOAT7,MAPK8,RET,IL17RB,SLC6A9,CCDC88A,SMARCC2,TMCC1,TSNAXIP1,CLASP2,INKA2,PLCB1,MTCL1,TCF7L2,PSD3,TIAM1,VLDLR" Drug CID000066666 poly(divinylbenzene Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ALDH7A1,DMPK,ST6GALNAC3,ATP8A2,MAG,PDCD2,MAPK3" Drug CID000150851 2'-fluoro-2'-deoxyuridine Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ITGAM,POLG,FEZF2,RET,RNASE1,ARHGAP9,TF" Drug CID000005026 AC1L1JG6 Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ALDH7A1,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,ENPP2" Drug CID000123783 AC1Q5JOY Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "BBS2,BOC,EPB41,DMTN,KCNF1,TAC3,NTSR2" Drug CID000089234 gamma-aminobutyrylhistidine Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ABAT,CP,ELAVL3,GAD1,GAD2,CNDP1,SLC15A2" Drug CID011469229 "quinoxaline-2,3-dione" Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "GLRB,PCSK1N,GRIA1,GRIA2,GRIA4,GRIK1,GRM3" Drug CID000009609 ethyl sulfide Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ALDH7A1,DBT,MAT2A,MID1,PBRM1,CLSTN2,ZEB1" Drug CID000211707 taurin Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "PDXK,CBS,AIFM1,CTH,FOXG1,PIK3C2A,SST" Drug CID000124514 beta-CCt Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "STX2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000025294 chloropyramine Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "EDNRA,CIT,HRH3,HNMT,PTK2,TAC1,TACR1" Drug CID000003299 ethyl loflazepate Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,JMJD6" Drug CID000009641 "2,2,3,3,4,4,5,5-octafluoro-1-pentanol" Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "CFLAR,SUMF2,STX2,GPR162,FUZ,STX1A,ST8SIA2" Drug CID000052396 P-81 Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "AGT,CALM1,CAMK2B,CAMK2D,KRIT1,MBP,MAPK3" Drug CID000235382 2-methyl-6-styrylpyridine Stitch 2.91E-03 1.00E+00 1.71E-02 1.95E-01 7 14 "ADORA1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8" Drug 2938_UP Alprostadil [745-65-3]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 2.94E-03 1.00E+00 1.73E-02 1.97E-01 36 145 "ABHD6,TKTL1,GRAMD1B,MTUS1,BIN1,DNAH17,CFLAR,ST3GAL5,LDLRAD4,CD86,CD38,CHN2,CREM,ABCG1,SIPA1L1,DOCK4,KLHL3,MAMLD1,FAM13A,PRKAG2,OLR1,PDE4B,PDE4D,SERPINI1,SMOX,QDPR,TMEM255A,SGK1,SPTAN1,SAMSN1,EPB41L3,PLCB1,TNFRSF1B,TRPS1,FLRT2,ZBTB38" Drug 7438_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "AP2A2,EPB41L5,APOC1,CDK10,RIPK1,BMP7,CCNT1,ARHGEF1,TAOK2,ZFYVE9,COL9A2,CSNK1E,EDRF1,DNM1,DPH1,DTNA,EGR3,PLEKHO1,FGFR3,GHR,FERMT2,MMP16,NFYA,PCDH9,PRKAR1B,LRRC49,RGS10,SAFB,SEC14L1,SH3BP2,BTBD7,SLC20A2,SMARCA4,CDK5RAP2,TMCC1,PHLDB1,TACC1,TIAM1,BEX4,TRPC1,ZMYND8,SSBP2,CADM1,PLPPR2,ST7" Drug 4303_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "NME5,PLA2G6,ALDH7A1,SPAG9,CDC42,SRSF11,RAB26,FAM169A,NR1D2,EDIL3,FCF1,MBNL2,ING4,SEMA4D,CRCP,RASSF8,AGFG1,IL6ST,MAP4,NFIX,NUMA1,PIK3R1,STRN3,LRP12,WDR25,PTHLH,SLC25A36,SEC14L1,FBXO11,CCDC88A,ZNF667,ARHGEF9,TBL1X,EHBP1,TCF4,TRIM2,PSD3,DICER1,TMPO,WNT7A,SF1,ZBTB38,WNK1,PRDM2,KAT6A" Drug 6718_DN Estradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "AP2A2,CDC42BPA,MADD,CDK13,SLC4A4,STX16,CANX,CBFA2T2,CHM,HOMER3,CREM,VCAN,CNTNAP2,TBC1D5,KIAA0753,EDIL3,FCF1,IRAK4,TUBD1,ETV1,KIAA1109,TRMO,OGA,DENND2A,ZMYND11,USP19,GPD2,NUDT21,MAP4K5,BACH2,INPP5B,KPNA5,CLDN11,GRAMD1C,PTK2,ZSCAN2,TMEM231,CLIP1,SLC14A1,TAB2,SS18,TCF4,ZEB1,TRPC1,PHTF2" Drug 991_DN retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "ABHD6,AP2A2,NCOA1,ADAM15,PLAA,QKI,ABCG1,GIT2,SGSM2,CELSR3,EGR3,STX2,KAT8,FGFR3,EVL,POMT1,SYT17,FERMT2,GPR37,GRB10,SLC2A6,BRINP3,KCNK1,MDM4,PCDH9,PIK3R1,RETREG1,PMP22,PKIA,LRRC49,RIPOR1,RAD51D,SEC14L1,ZFP30,SMTN,ZSWIM8,CAMTA2,TACC1,TBL1X,HEY2,PARD3,CADM1,UBTF,PMEPA1,HPS4" Drug 2227_DN Terfenadine [50679-08-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "AK2,ATM,ATP6V0A1,ADAM15,BTRC,CAMK2G,SRSF11,B4GALT6,ZFYVE9,AKAP7,EDRF1,CDON,FCF1,EGFR,DLC1,ZNF589,FER,CAMSAP1,DPYSL4,TXNL4A,RAB30,POLL,KIF3A,HNMT,BRINP3,KCNH2,MAPT,ADAM22,NFYA,CNOT4,NPTX1,NUMA1,PIK3R1,PLEC,STRN3,PTHLH,RNASEL,VPS13A,TACC1,SLC44A1,TMPO,ZMYND8,ZNF74,EMSY,PHTF2" Drug 2857_DN Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "CDC42BPA,APBB2,EIF4G3,ATP6V0A1,CACNA1D,SOCS6,B4GALT6,NIPBL,C2CD2,CREM,MED12,DSCAM,DTNA,DNAJB6,MBNL2,RGS17,VPS13B,DENND4A,BAIAP2,MALT1,GLYR1,KLC1,NEK1,NRCAM,PDE3B,C1orf109,ZCWPW1,ZDHHC14,RXRA,ATXN1,PPM1E,SHANK2,KDM4B,JMJD6,ARHGEF9,KAZN,MCF2L,IQCE,TBL1X,NSD1,PARD3,LMF1,ZBTB14,ZIC1,ACTR3B" Drug 1761_UP Syrosingopine [84-36-6]; Up 200; 6uM; HL60; HG-U133A Broad Institute CMAP Up 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "RBM10,AP1B1,C1QTNF1,PPFIA3,APP,ARRB2,CFLAR,LDLRAD4,RUNX1T1,CD86,CD38,JAM2,CREM,PPP1R16B,EXOG,NR1D2,SIDT2,SORBS3,MRNIP,POMT1,GPR153,GFER,OLR1,PDE4B,PDPK1,PLEC,FTO,SMOX,POLG,ZSCAN32,CCDC40,RGS12,SGK1,ELMO2,SLN,POGZ,SS18,ST5,TAC3,NSD1,TLR4,TNS1,RBFOX2,CADM1,FLRT2" Drug 6746_DN Calciferol [50-14-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "APP,CANX,CBFA2T2,QKI,WHRN,ARHGEF10,MICAL2,MFAP3L,KIAA0753,DLG3,DPH1,RCAN1,MBNL2,AASS,CDKL3,KIAA1109,ANKFY1,C1QL1,PRRC2B,NR3C1,GRM1,MEF2C,SCAMP5,PBX1,PC,PPP5C,PTK2,PID1,ZCWPW1,SH3BP2,LIMS2,SLC14A1,SS18,TRIM2,SZT2,SYNE1,AHCYL2,GPR161,UGT8,LMF1,ZBTB14,SH3GLB2,KCNAB1,PHTF2,AAAS" Drug 2771_UP Convolamine hydrochloride [500-56-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "LTBP4,APAF1,PPFIA3,ASPH,STX16,BACH1,CFLAR,ST3GAL5,CACNA1I,CFAP410,CACNA2D1,CACNG1,HAP1,CDC42,NMT2,FADS2,SIPA1L1,PHF14,DTNA,FCF1,SIDT2,AFF2,EFCAB2,GAB1,POLL,GNG3,NR3C1,ICA1,KHK,PDE3B,GRAMD1C,SNRK,ZSCAN32,ZDHHC14,SFPQ,SHANK2,SPTAN1,SS18,KAZN,DMXL2,ARHGEF12,TRIO,HIRA,EMSY,PHTF2" Drug 3926_DN Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 2.94E-03 1.00E+00 1.73E-02 1.97E-01 45 191 "NDRG3,NME5,LTBP4,EPB41L5,APOC1,CDC14B,SPAG9,USP2,CNTFR,MFAP3L,ATN1,LRRC23,KIAA1109,CAMSAP1,FHL1,RND1,SPIN1,HTATSF1,GSN,RASSF8,IL6ST,ITPKB,MAP4,MDM4,MMP16,NUMA1,PCDHGC3,PIK3R1,STRN3,PPP2R2B,PRKAB2,PRPH,RGS12,SLC25A36,NEK11,SEC14L1,PPP1R9A,EMC1,ZBTB43,EHBP1,SLC44A1,TMPO,SF1,WNK1,KAT6A" Drug ctd:D013654 Taurine CTD 2.94E-03 1.00E+00 1.73E-02 1.97E-01 33 130 "ACHE,ADORA2A,ADRA1B,AGT,ALAD,APAF1,DGKZ,ATP2A2,BID,KRIT1,CHN1,PPP1R16B,DCT,DMD,RASGRP1,FGFR1,CAP2,GRM7,GUCY1A1,HMGB1,HSD17B1,MITF,PPP2R5E,MAPK3,MAPK8,MAPK9,RPS6KA2,SCG5,TACR1,TEK,SIRT1,XRCC4,NDRG4" Drug CID000002160 amitriptyline Stitch 2.95E-03 1.00E+00 1.73E-02 1.97E-01 35 140 "SERPINA3,ADD2,ADORA1,ADORA2A,ADORA3,ADRA1D,ADRA1B,ADRB2,CACNA2D1,CHRM1,DMPK,DRD1,ZMYND10,GAD1,GAD2,GALC,LOXL3,NR3C1,CIT,HRH3,HNMT,HTR2A,HTR5A,KCNA1,KCNH2,KCNN2,KCNN3,MAOB,ABCB1,RET,SLC1A2,SLC1A3,SLC6A1,SLC6A11,TRH" Drug CID000002259 aurintricarboxylic acid Stitch 2.95E-03 1.00E+00 1.74E-02 1.97E-01 25 91 "ERBB4,GRIA1,GRIA2,GRIA4,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,IGF1,ITPKA,JAK1,JAK2,MAPK3,RNASE1,RNASEL" Drug CID009543473 C-1A Stitch 2.95E-03 1.00E+00 1.74E-02 1.97E-01 25 91 "ADCY6,DGKZ,DGKD,DGKI,CHRM1,DGKB,DGKG,RASGRP1,CALCRL,PTK2B,GLS,PKD1,POLG,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,PTK2,RDX,RNASEL,GSTCD,STX1A,TRIO,VAV1" Drug ctd:D003033 Coal Tar CTD 2.96E-03 1.00E+00 1.74E-02 1.98E-01 77 362 "ERMN,KIDINS220,ALCAM,BCAS1,CPNE5,ARNTL,PLA2G4C,CA4,CALM1,CHRM4,AKAP7,PHF19,GSDME,SLC29A4,NR1D2,FAM57B,ABCC5,EDN1,KLHL5,PHF20L1,DMTN,EPHA5,EYA1,PRAM1,POLK,STAU2,PNMA2,OGA,CPLX2,LYVE1,HTATSF1,CCDC184,DIDO1,PLCD4,SERP2,KIF3A,GSTM5,SLC2A6,CELF5,KCNA4,LDLRAD3,MDM4,KITLG,CD200,MSR1,THYN1,MYCN,NEUROD2,NFE2L2,NFYA,P2RX7,PBX1,PMP22,LAMA1,RAP1GAP,RGS12,ROBO2,PRR5L,ATXN7,PRCD,SHC4,MAGI3,RUFY2,SLC12A4,FNBP1,HECW1,SPTAN1,INKA2,SYNE2,PLCB1,ANKRD12,TCF7L2,NSD1,CA14,SLC26A10,REEP1,RGS7BP" Drug 2426_DN Progesterone [57-83-0]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 2.99E-03 1.00E+00 1.76E-02 2.00E-01 44 186 "ADRB2,CDC42BPA,PPFIA4,APOC1,SCAPER,CLGN,COL9A2,ARHGEF10,CX3CR1,HDAC9,DTNA,FAM13A,ING4,ENO2,RASGRP2,GAA,MAN1B1,NCKAP1L,LSS,SLC11A2,NUMA1,PFKFB3,PLCB2,PILRA,PRKCZ,CNNM2,SIDT1,ARHGEF10L,SBF1,GALNT10,SCG5,FAM102A,SLC2A5,FAM214B,SLC6A8,KDM4B,KDM3A,SPP1,PLCB1,KAZN,TCF7L2,TNS1,GDPD5,KAT6A" Drug 4327_DN Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 2.99E-03 1.00E+00 1.76E-02 2.00E-01 44 186 "NME5,APLP1,MARK4,ADGRB2,MYRF,CAMK2G,ARHGEF1,TAOK2,LHX2,PLAA,SMARCAL1,DCAF4,SNPH,RHOBTB1,ATN1,EIF5,EZH1,TBC1D16,ZNF589,FAM49B,DENND2A,GPER1,ATXN2L,ITPKB,MX1,OGDH,PDE4A,SAMD9,SH3TC2,MAP6D1,SH3BP2,ZNF365,SLC4A3,LIMS2,SMARCD3,CEP68,PHLDB1,ASTN2,ATP13A2,TMEM121,SPHK2,MAP3K12,HPS4,DPF3" Drug 5566_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 2.99E-03 1.00E+00 1.76E-02 2.00E-01 44 186 "FAM135A,AMPD3,BIN1,AMT,APBA2,CACNB4,EPS15L1,DNAJB5,WHRN,HAPLN1,CSF1R,EDRF1,DRD1,DYRK1A,ZNF391,ST3GAL6,CAP2,AFF2,ERAP1,SRCAP,GLS,IL6R,MYCN,NAP1L2,SLCO1C1,PGAM2,MAPK10,KLK6,RYR1,HSPA4L,SGK1,SH3BGR,CNKSR2,SNCA,TSPYL2,POPDC3,SEMA4A,TRPM2,VIPR2,VLDLR,LAT2,XRCC4,ZFP37,HRASLS" Drug CID000065366 baccatin III Stitch 3.01E-03 1.00E+00 1.77E-02 2.01E-01 13 37 "NCOA1,NCOR1,NCOR2,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,INPP1,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID003035793 AH 21-132 Stitch 3.01E-03 1.00E+00 1.77E-02 2.01E-01 13 37 "ADORA1,PDE8B,ALDH7A1,TUBB3,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000005193 secobarbital Stitch 3.01E-03 1.00E+00 1.77E-02 2.01E-01 13 37 "CNTNAP2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,MAPK3,SLC6A1,ZEB1" Drug CID000001830 I TU Stitch 3.01E-03 1.00E+00 1.77E-02 2.01E-01 13 37 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,ADORA3,AMPD3,ALDH7A1,GCK,MATN3,PTPA,PYGM,DDN" Drug CID000000204 allantoin Stitch 3.01E-03 1.00E+00 1.77E-02 2.01E-01 13 37 "ABAT,BRAP,AMPD2,AMPD3,ALDH4A1,PRC1,CHD1L,GDA,DPYSL2,GPD2,ZNF365,SLC6A1,EPB41L3" Drug CID000001189 NSC18930 Stitch 3.03E-03 1.00E+00 1.78E-02 2.02E-01 22 77 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,PDE8B,BLM,CNOT8,GDA,MBNL1,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PYGM,NSD1,AKTIP" Drug 5419_DN Methotrexate [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.05E-03 1.00E+00 1.79E-02 2.03E-01 43 181 "SLC12A5,PPFIA3,ARHGEF7,CACNA1D,SYNGR3,SOCS6,NECTIN3,AKAP12,DZIP3,TBC1D5,EIF5,PLEKHO1,ACSL4,KAT8,IP6K2,GCNT2,PSRC1,GPR19,NR3C1,ARHGAP19,MATK,GIT1,NF1,PDE3B,PLXNB1,TNPO2,MINDY2,PPM1B,PRKAR1B,WDR25,RAB3IL1,RGS3,RNASEL,DCUN1D2,SFPQ,ITSN1,URGCP,SMTN,JMJD6,PLCB1,TMEM121,VGF,HPS4" Drug 1175_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.05E-03 1.00E+00 1.79E-02 2.03E-01 43 181 "ALAD,APBB2,FAM131A,ST3GAL5,HIP1R,INA,CHN2,NMT2,STOML1,IQCK,PREPL,CRY2,PDE4DIP,DOCK4,KIAA0513,RIMS3,DNAJC6,BSCL2,CDKL3,EXTL2,TESK2,PCYOX1,RND1,RAB40B,GPR19,PADI2,IL11RA,KIF5C,SERPINI1,CCSER2,RPS6KA2,WDR47,PALLD,ZCCHC24,ZSWIM8,SPTAN1,CEP68,RGL1,STXBP1,CAMSAP2,HEY1,NPL,EVI5" Drug 4457_UP rosiglitazone; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.05E-03 1.00E+00 1.79E-02 2.03E-01 43 181 "ABHD6,PKP4,BRINP2,SLC2A11,NRP2,CDK5R2,KALRN,C2CD2,OSBPL3,EDRF1,C2CD2L,DTNA,SGK2,FOXG1,SORBS1,FYB1,GAD2,LPAR4,GRK4,ATXN2L,IRF8,ITGA7,KCNF1,KCNH2,ADAM22,PDGFRA,GPR85,FA2H,CEP41,ACSS3,RGS4,KIRREL1,TCP11L1,SCN3B,ARHGAP26,ELOVL4,ACSBG1,KAZN,TGFBR3,VLDLR,ZIC3,REEP1,SLC17A7" Drug 2930_UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.05E-03 1.00E+00 1.79E-02 2.03E-01 43 181 "TKTL1,ACTN2,MTUS1,DOC2A,AMPD3,BIN1,CDC42BPA,ANK3,DNAH17,DDX3Y,MPDZ,CAMK2B,CD86,CD38,COL9A3,CREM,ABCG1,MICAL2,SIPA1L1,PPP1R16B,DOCK4,CNNM1,SCARA3,KHDRBS3,GAD2,GRIK5,KIT,MAP4,MAPT,ZNF862,NINJ2,OLR1,PDE4D,SLC25A23,MAPK7,SYTL2,RXRA,ZNF821,BTBD7,ARHGAP26,LHPP,PLCB1,UGT8" Drug CID000160263 AC1Q6P06 Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,SLC12A2,TUBB2A,TUBB1,TUBA1A" Drug CID000105078 beta-CCE Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "ADORA2A,CA4,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,SST,ZEB1" Drug CID000003773 isonipecotic acid Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "ALDH7A1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PPARA,SLC6A1,SLC6A11" Drug CID006918545 CA1P Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "CA4,HEPH,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB1,TUBA1A" Drug CID006438440 55623-37-5 Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,NBL1,TUBB2A,TUBB1,TUBA1A" Drug CID006439188 MDL 27048 Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,PTK2,TUBB2A,TUBB1,TUBA1A" Drug CID000031276 isoamyl acetate Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "ACHE,ABHD6,NR0B1,CCK,ATP8A2,KCNH1,MYO7A,POLR2F,RDX,FTSJ1" Drug CID000033630 hydroxamates Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "CACNA1I,CACNA1G,CACNA2D1,CALM1,CALN1,DRD1,HTR2A,KCNK2,TRH,SEMA3B" Drug ctd:D014236 Trichlorfon CTD 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "SERPINA3,ACHE,APP,BCHE,CHRM4,GAP43,NEFH,NFE2L2,SYN1,SYP" Drug ctd:C121465 6-methyl-2-(phenylethynyl)pyridine CTD 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "ACHE,PPP1R1B,GAD1,GRIA1,GRIN1,GRM1,GRM5,PDYN,PENK,MAPK3" Drug CID000196989 allocolchicine Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "TUBD1,TUBB3,TUBB4A,TUBA8,LYVE1,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000073427 NSC142227 Stitch 3.05E-03 1.00E+00 1.79E-02 2.03E-01 10 25 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MAOB,TMEM132D,TUBB1,TUBA1A" Drug CID000093138 AC1L3PKS Stitch 3.05E-03 1.00E+00 1.79E-02 2.04E-01 26 96 "DPP10,APP,AZGP1,RHBDL1,CHGA,SUMF2,ERBB2,TUBA1B,FGFR3,FOLH1,LNX1,CNDP1,MMP16,MX1,NASP,SERPINE2,NOMO2,PTN,RET,SHC4,SLC6A8,SLC14A1,TACC1,CADM1,SCG2,ST8SIA2" Drug CID005459392 Thiophosphonoacetic Acid Stitch 3.05E-03 1.00E+00 1.79E-02 2.04E-01 26 96 "ANK1,ANK2,ANK3,SPTBN4,NRP2,CRLF1,SLC22A6,CLU,COL4A5,RASSF2,NTM,DNAH9,CASP8AP2,ENO2,EPHB1,GPHN,FOXM1,LOXL3,SCRG1,MAOB,CD200,PTPRN,PTPRN2,PID1,RBBP8,SEMA3B" Drug CID000005212 sildenafil Stitch 3.05E-03 1.00E+00 1.79E-02 2.04E-01 26 96 "PDE8B,ALDH7A1,CACNA2D1,RHBDL1,CHRM1,CNGA3,ABCC5,EDN1,EDNRA,EDNRB,CIT,GUCY1A2,GUCY1B1,NOS1,NPR2,PDE1A,PDE1C,PDE2A,PDE4A,PDE4B,PDE4D,PDE1B,MAPK3,MAPK4,MAPK7,SEPT3" Drug CID000000984 hexadecanal Stitch 3.07E-03 1.00E+00 1.80E-02 2.05E-01 52 228 "ACADM,ABHD6,KDM5D,PLA2G6,BBOX1,GPAM,LDHD,CERS5,DLGAP1,NUMBL,PPT2,TPP1,FADS2,COL9A2,CS,CYBB,CEP170,SV2A,DLG4,ACOT8,EPB41L1,PIPOX,PCYOX1,FOLH1,RASL10A,NEURL4,STARD10,GCK,PPARGC1A,POLL,LPAR4,WIF1,ACOT7,HMX1,CPT1C,MARK3,PC,PCDH8,ENPP2,PPARA,RGS10,RPE65,RTKN,SCP2,MRAS,SH3GL3,SLC12A4,ST5,SYP,FTSJ1,PLPPR5,NETO1" Drug ctd:D002713 Chlorine CTD 3.08E-03 1.00E+00 1.80E-02 2.05E-01 78 368 "ACADM,ADCY2,ADCY5,ADCY8,ADORA3,ADRB2,AMPH,APC,ARRB2,ATP1A1,NRP2,CACNA1A,CACNA1B,NGB,CAST,CCKBR,CDC25B,CHRNA4,NRXN1,NRXN2,CLU,CNN3,CNR1,CSF1R,SIRPA,SV2B,DPP6,DRD1,EDN1,EIF5,FGR,HPCAL4,GABBR1,GALR1,GHR,GNAO1,GNAS,GRIN1,GSTT2,ACOT7,IL12A,KCNA4,KCNB1,KCND2,KCNJ4,KCNJ5,SMAD1,NELL1,NELL2,NOS1,PDE4D,PFKFB4,PLEC,PMP22,MAPK3,PTAFR,PTN,RALGDS,SLC6A15,STX1B,SCN2B,SCP2,SGK1,SLC1A6,SLC6A9,RIMS1,SNAP25,UNC5B,SST,SYT11,SYP,SYT4,CDH22,NR2C2,AMACR,NTSR2,VIPR2,TUBA1A" Drug ctd:D009966 Orphenadrine CTD 3.09E-03 1.00E+00 1.81E-02 2.06E-01 82 390 "METAP1D,PLEKHH1,ADORA1,ADORA2A,ADRB2,ABCD2,APP,ZBTB10,ATP2B2,SYNJ2,MYRF,IL33,MTMR7,B4GALT6,ARHGAP22,NRXN1,TMEM184B,MAP4K4,TOGARAM2,ARHGEF10,ATRNL1,SDC3,NOS1AP,SPOCK2,DPP6,CALCRL,MTSS1L,ADGRV1,F8,ARMCX1,EFEMP1,AMOTL2,MEX3B,IP6K2,FLT1,CGREF1,RND1,TOX3,LILRB4,CNDP1,GPR17,GRIK5,IGFBP1,KCNH2,NCOA7,MID1,NEFH,NINJ2,NPY,DNHD1,ZDHHC8,SNX10,PMP22,IRX1,PPP1R1A,SIDT1,PTPRN,ERI2,ACER3,MAPK12,IL17RB,MRAS,SGK1,FAM102A,ABLIM3,SLC6A8,SLC12A4,ZNF334,BTBD7,UNC5B,DIP2A,STXBP1,GSE1,TBCEL,AZIN2,CSMD1,TNS1,TPM1,TRPM2,FNDC5,VAV2,PMEPA1" Drug CID006918637 taltobulin Stitch 3.11E-03 1.00E+00 1.82E-02 2.07E-01 12 33 "ABCG2,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,STMN1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID000033039 18F-FLT Stitch 3.11E-03 1.00E+00 1.82E-02 2.07E-01 12 33 "DNAH9,FLT1,GNAS,PTPN5,HP,HPR,OPA1,POLG,DDN,TK2,SMUG1,TSN" Drug CID005311003 alpha-neoendorphin Stitch 3.11E-03 1.00E+00 1.82E-02 2.07E-01 12 33 "CA4,NPY,NUMA1,OPRL1,PCSK5,PCSK2,PDYN,PENK,SELL,SST,RGL1,TAC1" Drug CID003481669 AC1MQSA5 Stitch 3.11E-03 1.00E+00 1.82E-02 2.07E-01 12 33 "CA4,LRBA,SUMF2,BOC,CHRDL1,AGFG1,IL11RA,KCNH2,PDYN,SELL,TAC1,TACR1" Drug ctd:D015761 4-Aminopyridine CTD 3.11E-03 1.00E+00 1.82E-02 2.07E-01 12 33 "ADRA1B,NCOR2,DPYSL4,GAD2,GRIN2D,KCND3,KCNH2,MAG,MAPK3,KCNIP1,SYN1,JPH3" Drug CID000134739 ddGDP Stitch 3.13E-03 1.00E+00 1.83E-02 2.09E-01 11 29 "BRAP,NME5,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TMEM132D,TUBB1,TUBA1A" Drug CID000003277 etazolate Stitch 3.13E-03 1.00E+00 1.83E-02 2.09E-01 11 29 "ADCY5,ADCY6,ADCY8,ALDH7A1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PDE4B" Drug CID000005504 tolazoline Stitch 3.13E-03 1.00E+00 1.83E-02 2.09E-01 11 29 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,HRH3,ATXN2L,POU3F2,RPE" Drug ctd:D000393 Air Pollutants CTD 3.14E-03 1.00E+00 1.84E-02 2.09E-01 175 918 "DGCR6,AS3MT,NDRG2,ADD3,ZNF608,NR0B1,TXNDC16,CEP126,CARNS1,MARCH4,APAF1,GPAM,CDC14B,ARRB1,ARSE,PTCH2,ATM,RNF182,ARHGEF7,SCAPER,CASTOR3,C5,IL33,CA12,CACNA1D,CACNA2D1,CALB1,CAMK2D,INA,SCARB1,LRBA,DCLK1,LRRFIP1,LARGE1,CCPG1,FOXN3,TJP2,ABCG2,FAM149A,SLC25A27,LETMD1,CREB5,AKAP12,LRIG1,MICAL2,VCAN,DZIP3,CTNND1,CX3CR1,CCDC144A,TBC1D5,DAPK1,ELMO1,HP1BP3,RHOBTB1,HS3ST2,USP3,CD99L2,NR1D2,DNAJB6,EIF4G1,ING4,SRPK3,EPB41,RAB9B,ERBB2,NCALD,TMEM74,F3,NSRP1,FAM198B,RPS6KC1,GTF2IRD2,KIAA1109,FHL1,IP6K2,NBEA,ARFGAP2,GAB1,GABRA5,FAM184B,AHCYL1,ZNF234,IQGAP2,ERAP1,GATM,TUBA8,GFAP,PPARGC1A,GK,RND1,GLS,MSL3,EML4,PRDM5,HAS2,FRMD3,TNFAIP8L3,HMGCL,HNF4G,LIG4,MATN2,MEIS2,MIA2,AFDN,SESN3,CCDC80,BCO1,PTOV1,NAP1L2,NFIA,NFE2L2,OGG1,OPHN1,OXTR,ETFRF1,PCDH9,PDE3A,PFKFB3,SERPINE2,SMOX,PLXNB3,MAPK8,CNNM2,SAMD9,BCAS3,VPS13C,SPDL1,PTPRD,RAP1GAP,ARID4A,RFX5,ZFHX4,CARF,ROBO1,PCMTD2,CCDC102B,MRAP2,NEK11,PTGR2,FNIP1,HKDC1,ST6GAL1,LIMS2,CDK5RAP3,SCMH1,CXXC4,SPATA7,KDM3A,NMNAT2,SPP1,PBLD,ITPRID2,ADHFE1,SYNE2,TMEM136,DMXL2,SLC19A3,USP32P1,TNS2,TP53BP1,ANO5,SSBP2,TST,GORASP1,PLEKHH2,XRCC4,KCNT2,TRIM9,FSTL5,PMEPA1,CADM2,NAV3,MARCH8,FRMD6" Drug 991_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.14E-03 1.00E+00 1.84E-02 2.09E-01 41 171 "SERPINA3,MTUS1,ARRB1,PDE8B,CACNA1D,SLC4A8,TENM4,CSF1R,PDE4DIP,ATN1,EPB41L1,CAMSAP1,RAB30,LMO2,MAG,MEIS2,PBX1,PFKFB3,KLK6,RAB3A,RAP1GAP,RNASEL,EMID1,SELL,SLC22A4,LIMCH1,RBM34,MAPK8IP3,AJAP1,TRIM2,AP4E1,KAT6B,CABIN1,CDK20,NPL,RPRM,VGF,GDPD5,SCG2,SEMA3B,NAV2" Drug CID000031645 pirimicarb Stitch 3.15E-03 1.00E+00 1.84E-02 2.10E-01 16 50 "ACHE,SLC4A4,BCHE,CACNA1A,LARGE1,CS,BOC,ATN1,DTNB,ICA1,PTPRN,RBBP8,ATXN1,ATXN7,TBL1X,TTPA" Drug CID000002534 NSC611747 Stitch 3.18E-03 1.00E+00 1.85E-02 2.11E-01 75 352 "ACTN1,SLC12A5,ADRA1B,MYH7B,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,AIFM1,LRBA,CDR1,SLC22A6,MYL6B,AKAP12,CSNK1E,CALY,DBN1,SLC12A6,RPS6KC1,PPP1R1B,ACTL6B,HBS1L,INPP5K,CSDC2,RND1,GRM1,GRM5,HP,HPR,MYLK2,KCNK3,KCNN3,MAPT,MBP,PPM1L,MYH3,MYH6,MYH7,MYL3,MYO5A,NCF2,ODF2,PDE1C,PDE3B,PDPK1,PLIN1,PPM1B,PPP1R1A,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,PPP2R3C,RPS6KA2,MAPK12,SCN2A,SMPD3,SLC12A2,SLC12A4,SLC14A1,NSFL1C,MLC1,ACTR6,CABIN1,TRPC1,TRPC3,WNK3,GOPC,NUP214" Drug 3070_DN Metyrapone [54-36-4]; Down 200; 17.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABAT,ADORA3,C1QTNF3,APC,BCL7A,SYNJ2,MTMR2,SLC16A4,AP4M1,EPS15L1,BAG4,VCAN,ZNF337,EXOG,MRNIP,RRAGB,ZNF589,FECH,FAM49B,ATP2C1,GPR19,CACFD1,ZNF862,NF1,NUMA1,ODF2,PLCB2,MAPK8,PTAFR,MAPK12,HSPA4L,BTBD7,SLC20A2,ZCCHC24,EMC1,RBM26,ARHGEF9,CAMSAP2,SMUG1,TRPS1,PLPPR2,REEP1,PRDM2,KCNAB1,PARP11,PHTF2" Drug 427_DN iloprost; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,SLC12A5,ADORA3,ARRB1,PDE8B,ADAM23,ADAM15,ARHGEF7,HAP1,ARHGEF2,CHRM4,PICK1,CNTN1,DAPK1,DSCAM,TOM1,SIDT2,EFNB3,EPB41L2,TUBB4A,NEU3,RUNDC3A,MCHR1,PTPRT,NXPH3,ITIH2,VWA5A,CCSER2,MAPK10,SH3BP2,SH3GL3,SLC2A5,PKNOX2,ELMO2,KDM4B,NMNAT2,CDK19,PLCB1,CHST5,TRIO,VAV2,ZIC1,WNK1,VPS35L,SLC17A7,EPM2A" Drug 7500_UP "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AP2A2,AK2,ALCAM,APLP1,PPFIA3,CFLAR,CAMK2B,CAMK2G,NEURL1,SRSF11,SLC4A7,FEM1B,EFNB3,CELSR3,EIF5,ENO2,RASGRP2,BAIAP2,ALDH1L1,MALT1,COPS8,GLS,HTATSF1,POLL,ADAMTS13,TJAP1,MGAT3,NEK1,CDK18,FAM120C,KCTD17,ROM1,SCN8A,SYBU,KDM4B,PEG10,CDK19,STX1A,VAMP1,PCDHA5,AHCYL2,TRIO,MICAL1,KCNK12,MAP3K12,PCBP4" Drug 424_DN LY294002; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "BRAP,DGKD,ARNTL,SLC4A4,BMP7,CALB2,CHN2,JAM2,IFFO1,SH2B1,KIAA0513,DBT,RCAN1,SORBS3,LRRC23,FKTN,KAT8,AFF2,GABRA4,GAD2,AHCYL1,SRCAP,GLS,MYT1,NEUROD2,CNOT4,NPPA,NTRK2,NTRK3,PHKG1,FSD1,BSDC1,RGS3,RLBP1,CCDC25,ATXN2,SLC2A5,DBNDD2,SYN2,DMXL2,SPX,TNNT1,ZKSCAN5,UBE3A,VSNL1,NUP214" Drug 6747_DN Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "BIN1,APLP1,APP,STX16,ADAM23,LDLRAD4,CANX,CBFA2T2,RAB28,NRXN3,WHRN,MICAL2,CNTNAP2,BRINP1,PARD6A,SPOCK3,SIDT2,EFNA3,CELSR3,AASS,SORBS3,DMTN,TUBB4A,GLI2,LPAR4,GRM1,IL6ST,MGAT3,MYT1,NF1,NOVA1,PLXNB1,MAPK7,SAMD9,KHDRBS2,RGS10,SBF1,ASAP3,PEX26,LHPP,STX1A,ARHGEF12,TIAM1,TRPC1,EVI5,PHTF2" Drug 2011_DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; HL60; HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,PLA2G6,PKP4,APP,N4BP2L1,CFLAR,CANX,CARS,ARHGEF1,CHRNB2,ZFYVE9,CST3,INTS1,DCTN1,ZNF804A,DTNA,ABI2,CINP,UFM1,GAP43,GRIK5,KCNN1,KIF2A,KLC1,AFF1,MTR,SETD4,ENPP2,GPSM2,PLCD1,MBOAT7,CNNM2,BSDC1,MYH14,CCDC88A,ZSWIM8,RGL1,DIP2A,GANAB,TCF4,SIRT1,SPX,METTL3,LAT2,ZNF142,SMIM8" Drug 1803_DN Epirizole [18694-40-1]; Down 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBB1,APP,CDK10,SEMA4G,MARK4,SCAPER,SCARB1,PLEKHB1,SLC4A7,CSF1,RUSC2,PARD6A,SLC12A6,FEM1B,EFNA3,COQ7,VPS26C,SCML2,FGFR1,CINP,CGREF1,SRCAP,FERMT2,GPER1,KIFC3,GIT1,MX1,ZNF862,PC,CDIP1,FA2H,PTPA,RPS6KA2,MAPK12,ASAP3,FUZ,KDM4D,SIRT2,CAMTA2,MAPK8IP3,ARHGEF12,LMF1,UPF3A,WNK1,PRDM2,URM1" Drug 6390_UP 5707885; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ACTN2,ARID1A,C1QTNF3,ALK,ASPA,ADAM23,THSD7A,CBS,CBFA2T2,ARHGEF2,MAGI1,ABCG2,CHD5,SLC12A6,ATN1,DSCAM,EDN1,LRRC23,STX2,ETV1,FGFR1,ZNF44,POLL,GNAS,HLF,HSF2,SNTG1,PDE4B,PENK,PFKFB4,MINDY2,PPP5C,RNASEL,CARF,STUM,SLC1A7,SLC6A11,SLC8A1,SCN3B,HECW1,UNC5B,ATP10B,KIAA1107,PCDHGA1,R3HDM1,SLC17A7" Drug 7553_DN CP-863187 [668981-07-5]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "FAM131A,BAIAP3,CAMK2B,MAGI1,CRLF1,JAM2,RAB33A,QKI,HOMER3,NCOR2,EDRF1,DAPK3,EIF5,COQ7,CAMSAP1,KCNMB4,GNG4,NXPH3,ATXN2L,ELOVL5,KCNN1,MATK,MIA2,AFDN,MSI1,PC,PDE3B,RETREG1,LRP12,PACSIN1,PPP3CC,PEX5,RAB3IL1,MYH14,TCP11L1,FOXRED2,SIRT2,ZKSCAN3,SMARCD3,SNCA,SP4,PBLD,ITPRID2,ZKSCAN5,SLC26A10,REEP1" Drug 2812_DN Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABHD6,ARID1A,KIDINS220,PKP4,ASPH,RIPK1,CACNA1D,PTBP2,SYNGR3,CD81,CDC27,PLEKHB1,CNOT8,QKI,SLC4A8,CTNND2,PPP6R2,DTNA,RBM12,KIAA1109,BAIAP2,ERAP1,ARHGAP19,HNMT,JAK2,KCNJ3,MAPT,KITLG,MITF,CNOT4,SMOX,PMP22,PTPRE,TMEM231,REV3L,ARHGEF10L,SLC25A36,TACC1,TBL1X,HIRA,UBE3A,EVI5,HPS4,MPPE1,SMIM8,SSPN" Drug 3820_DN Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "DPF1,ADCY2,APOC1,ATM,ATP1A3,NRP2,BMP7,BTRC,CACNB2,CBS,SEPT7,FOXN3,QKI,AKAP7,AKAP5,SLC4A7,TBC1D5,DAPK3,DNM2,EIF4G2,KIAA1109,FGF1,HTATSF1,GNAS,GNG3,ICA1,JAK2,KCNB1,KCNMA1,LIFR,LYRM9,NEUROD1,PDE4A,PDE4B,SPATA6,PPARA,PTPRN2,RGS4,KCTD17,RXRA,SNCA,KAZN,ROBO3,VGF,VIPR2,EPM2A" Drug 6271_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,AMPD3,ANK3,SEMA7A,GAS7,CDC14B,PPP4R4,ALDH4A1,CFLAR,CACNG1,CACNA2D2,TAOK2,MFAP3L,DTNA,SGK2,IRAK4,MTSS1L,ACSL4,BAIAP2,B4GALNT1,USP19,RAPGEF1,SPACA9,CACFD1,HMGCR,KCND3,NF1,NPR2,STRN3,LRP12,PPP2R5C,MAPK7,CNNM2,PLPPR1,ROM1,HKDC1,ZNF430,SHANK2,MAPKBP1,EXOC7,AHCYL2,PIK3R5,TRPC1,PLPPR2,VIPR2,SLC13A3" Drug 6692_DN Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RALGAPA1,AP2A2,TRMT9B,APBB2,APOC1,PDE8B,NCOA1,MYRF,SRSF11,NMT2,DBT,KLHL3,SMG7,SGSM2,EDNRA,OPTN,ING4,DENND4A,ETV1,ANKMY1,IQCG,GPER1,PCLO,GUCY1B1,MTR,NDP,NUMA1,OPA1,OPCML,MED1,PPP2R5C,GRAMD1C,PTN,SH3TC2,FAM184A,ZDHHC14,TRAPPC13,CHD9,KDM4D,SLC20A2,LIMCH1,TROVE2,KIAA1107,TCF4,SIN3B,HIRA" Drug 7429_DN "Dropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADCY6,OSBPL1A,APOC1,MPDZ,BCL7A,C5,B4GALT6,CSNK1E,EDRF1,KIAA0586,DMPK,DNM2,ATN1,GNE,KIAA1109,SEPT9,SRCAP,HSD17B1,IPO5,PC,PCDH9,PLEC,SMIM7,PLXNB1,CEP97,RGS3,MAP6D1,SH3BP2,EPN2,CDK5RAP2,RCOR3,RAP1GAP2,PBLD,CEP68,MCF2L,EXOC7,ZKSCAN5,HIRA,CADM1,PLPPR2,ZNF45,ZNF142,UBE3B,NUP214,ZNF248,GAN" Drug 5057_UP Torsemide [56211-40-6]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "DPF1,SYT13,BIN1,APAF1,STX16,FUBP1,CACNA1I,HAP1,TAOK2,CLCN4,RAB26,TNK2,COQ7,FGF1,FGFR1,PRELID3A,HBS1L,SRCAP,GRM7,TJAP1,ITGA7,TM6SF1,MSI1,NF1,NPPA,PLCD1,PTPRN2,ACSS3,RGS10,KCTD17,SUGCT,TMEM206,IL17RB,SELL,SLC11A1,SPTB,NCDN,PHLDB1,TAL1,TBCEL,R3HDM1,ZMYND8,LAMP5,SEMA3B,KCNAB1,MVB12B" Drug 3401_DN Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "LTBP4,BIN1,CNTNAP1,APBA2,APC,APOC1,PPP4R4,CADM3,SYNJ2,BAIAP3,CACNA1D,CACNG1,STOML1,SH2B1,NCOR2,NOS1AP,DMPK,F3,OGA,ALDH1L1,INPP5B,KCNJ5,VWA5A,MAP4,KITLG,MSI1,PTPRO,TCP11L1,RPS6KA2,ASAP3,SLC1A2,BTBD7,LIMCH1,ZCCHC24,DOK5,INKA2,PLCB1,DOCK9,CRTC1,TGFBR3,TK2,UCHL1,VIPR2,REEP1,SYNC,ITM2C" Drug 994_DN 2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABAT,CDK10,ASPH,ATP2B1,CFLAR,NAE1,EPS15L1,RAB28,CLTB,CSNK1E,CTH,DBT,FBXL5,PARD6A,SGSM2,MED12,ATN1,FEM1B,DENND4A,KAT8,SEC24B,ATP2C1,INPP5K,MUM1,DHX35,MKLN1,NRGN,NLE1,PLEC,PMP22,RETREG2,PPP3CA,NKAIN1,MAPK12,SFPQ,ZFP30,SLC15A2,ZBTB43,NCDN,GANAB,TACC1,HEY2,KAT6B,UBTF,MICAL1,ST7" Drug 255_UP dexamethasone; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,CDC14B,ARNTL,CHRD,CADM3,CACNA1A,HAP1,HIP1R,RGN,CHN2,CHRNB2,TAOK2,NCAN,KLHL3,SRGAP3,SIDT2,PLXNC1,TXNL4A,GPER1,GRIN1,GRM1,PADI2,NCKAP1L,VSIG4,KCNJ5,MMP17,PDE4D,EPN1,PPP2R2B,CEP41,PTCH1,ZSCAN32,RAB3A,C1orf54,FAM184A,GSTCD,SLC8A1,SLC11A1,TNIK,MAPK8IP3,FAM208A,TMEM151B,PCDHA5,TRPC1,TMPRSS5,CLIP2" Drug 1702_UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ATM,STX16,ADAM23,GYG2,CRLF1,B4GALT6,SLC4A7,SLC4A8,SH2B1,NCOR2,TBC1D5,GIT2,HP1BP3,NR1D2,EIF5,DMTN,BAIAP2,GNG4,TDRKH,GRM1,ATXN2L,ELOVL5,HSF2,INPP5B,MAP4,NF1,ODF2,PCDH9,PLCD1,LRP12,RGS10,FBXO11,SLC6A8,BTBD7,CXXC4,LIMCH1,ZCCHC24,EMC1,CDK19,SPART,THSD1,NXT2,CEP68,TMPO,ZKSCAN5,GAN" Drug 7419_UP Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBB2,APP,ARNTL,MARCH3,ALDH4A1,SLC4A4,USP2,QKI,AKAP7,ENTPD4,CTNND2,INTS1,GIT2,MFAP3L,HP1BP3,DRP2,MRNIP,COQ7,ERCC2,SEMA4D,ZNF276,GLYR1,POLL,GPD2,RNFT2,MBD1,NFYA,SETD4,OXTR,MBOAT7,MAPK7,PEX5,SCP2,CXXC4,SNCA,KDM4C,ARHGAP26,ELOVL4,SEPT8,PLCB1,KAZN,TCF7L2,EVI5,GDPD5,MVB12B,SSPN" Drug 6017_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AK2,FAM131A,CDC14B,NCOA1,EIF4G3,BCL7A,MTMR3,GYG2,BTRC,SYNGR3,QKI,BAG4,CNTNAP2,GREB1,DCAF8,LYPD1,RHOBTB1,DTNA,EEF1A2,FYN,GABRA2,GHR,GLYR1,MSL3,NR3C1,SLC2A6,IL6ST,INPP5B,ITPKB,KCNF1,MAP4,NF1,SMIM7,PRODH,RIPOR1,SH3BP2,SMTN,ZNF430,BTBD7,SPTAN1,PLCB1,ATP11A,ANKRD12,TCF7L2,TPD52,SSBP2" Drug 2974_DN Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,AP2A2,CFLAR,SYNJ2,SGCE,CAMK2G,CLGN,IQCK,MICAL2,PDE4DIP,PPP6R2,RUSC2,SGSM2,SIDT2,STX2,CD320,F3,FCGRT,ZNF589,FER,FGFR1,PDLIM5,INPP5K,SRCAP,ADAM28,DIDO1,ELOVL5,IL11RA,ITGA7,MAP4,OGG1,PDE3B,MAPK8,RGS10,RPS6KA2,SH3BP2,FBXO11,SLC1A7,PALLD,ZCCHC24,KDM4C,KAT6B,ZKSCAN5,FLRT2,TRIM9,KCNAB1" Drug 2569_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABAT,BIN1,SYNJ2,CPS1,CSNK1G3,SIPA1L1,SOCS5,GSDME,SIDT2,FAM13A,PLXNC1,ST3GAL6,TESK2,ZNF44,ERAP1,ICA1,ITGAM,KLC1,MEF2C,MIA2,CCSER2,RETREG1,ZNF426,PTPRO,GALNT10,MRAS,SH3BP2,ITSN1,ZCCHC24,IZUMO4,DBNDD2,FAM168A,ADGRL3,TCF7,SZT2,SYNE1,SLC44A1,KCTD2,RBFOX2,TPD52,VIPR2,LMF1,XRCC4,ZNF24,EVI5,WIPF2" Drug 3004_DN Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "C3orf14,ACTN2,APBB2,ZFYVE9,ABCG2,DNAJB5,CSNK1E,ZNF337,CTIF,DYRK1A,AASS,SORBS3,MRNIP,RASGRP2,ERAP1,SIGLEC8,SEPT9,WASF3,GNAS,PRUNE2,GPM6B,LILRA2,GRM7,MAP4,MAPT,PTCH1,RAB3A,KHDRBS2,TCP11L1,FAM102A,FRMPD1,IQSEC2,DDN,MAPK8IP3,STX1A,DOCK9,PSD3,TNNT1,CDK20,OSBP2,VAV2,BEST1,MAP3K12,SEMA3B,PCBP4,NUP214" Drug 4566_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "DPF1,ASIC1,ASPH,KIF1A,RGS9,NRP2,CACNG1,CHRNB2,ARHGAP22,AKAP6,MYRIP,SUSD5,CNTNAP2,PPP1R16B,NOS1AP,ARNT2,ZNF549,GNAO1,GPM6B,GRIN1,CACFD1,SOX21,KCND3,MBNL1,AFDN,NCAM1,NEFM,NEUROD1,PDE4D,GPR85,PHKG1,PPP2R2B,MAPK4,ACSM5,ZMAT4,SCN2A,SH3BP2,FRMPD1,NLGN1,PKNOX2,NACAD,ARC,TACR1,PCDHGA10,HIF3A,TLR4" Drug 2871_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,KIDINS220,APBB2,GYG2,RCHY1,CRY2,ABCG1,SOCS5,FAM169A,DAPK3,HIPK3,SORBS3,ING4,RRAGB,ZNF589,MSL3,GPR19,HSD17B1,IL6ST,INPP1,KCNH2,MEIS2,ADAM22,NEK1,PPM1B,PPP5C,CNNM2,FOXRED2,PEX26,PPP4R3A,ZKSCAN3,KDM4B,DOP1A,SOX2,LHPP,MAPK8IP3,CEP68,TPD52,PLPPR2,SF1,ZNF74,DNALI1,EPM2A,ST7,ACTR3B,SENP7" Drug 4622_DN N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,AMT,PPFIA4,KRIT1,PLEKHB1,B4GALT6,RAB28,ABCG2,IQCK,BAG4,CNTNAP2,PPP6R2,DCAF4,BRINP1,KBTBD11,DTNB,FAM13A,MRNIP,RGS17,STX2,EFEMP1,GLYR1,GNAL,INPP5B,PLXNB1,GRAMD1C,PRPH,GON4L,CNTLN,PTPRB,FBXW7,ZFP30,ASAP3,SLA,SLC1A7,PEX26,SPTAN1,ST5,JMJD6,PLCB1,EXOC7,TPM2,AMACR,MAP3K12,EMSY,HPS4" Drug 5493_DN Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "SLC12A5,AP2A2,AK2,PPFIA3,DNAH17,NCOA1,SLC4A4,SCAPER,CACNA1D,LHX2,ZFYVE9,APPL1,DCAF8,ZNF337,EXOG,CNNM1,PLEKHO1,DLC1,FGFR1,DPYSL4,GPR19,AGBL5,IDH3A,MPP2,NFYA,NLE1,LRP12,PRODH,RAD51D,RXRA,SBF1,IL17RB,SUPT20H,SIRT2,KDM4C,ERC1,PHLDB1,POPDC3,TBL1X,KCTD2,CABIN1,TPM1,REEP1,UPF3A,HPS4,MPPE1" Drug 6263_DN Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBB2,EPB41L5,FAM131A,ATM,ATP6V0A1,KIF1A,OSGIN2,CNOT8,ZFYVE9,ARMC8,DZIP3,MFAP3L,SMG7,CELSR3,SORBS3,ANKMY1,FHL1,GLS,GNG4,GRB10,ELOVL5,HSF2,INPP5B,IPO5,MBD1,SLC11A2,SETD4,PIK3R1,MBOAT7,PPP2R2B,TMEM104,PEX5,TMEM231,RAB3IL1,ZDHHC14,FOXRED2,BTBD7,SMARCC2,WDTC1,UNC5B,CEP68,HIRA,ZNF24,NDRG4,REEP1,MPPE1" Drug 1789_UP Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "CNTNAP1,SCAPER,BAIAP3,CANX,CLDN10,NMT2,CRMP1,AATK,VCAN,HP1BP3,DYNC1I1,DNM2,SGK2,EFNB3,TRMO,CAMKK2,FYB1,HBS1L,GALC,GLS,PRRC2B,TDRKH,EML4,ACOT7,KHK,KIF5A,NEUROD2,NOS1,PALM,CCSER2,PACSIN1,PRKACB,RAD52,ARID4A,CLIP1,FAIM2,TMCC1,ZHX3,THSD1,FCHO1,NSD1,TLR4,RBFOX2,CA14,VSNL1,XRCC4" Drug 3065_UP Primidone [125-33-7]; Up 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASCL1,PDE8B,ALDH4A1,CCDC181,CACNA1I,MYRF,MTMR7,DGKI,CDH10,LHX2,CLU,CNTFR,RIPOR2,C2CD2L,ST8SIA3,EDNRB,PLXNC1,RASGRP2,CORO2B,GAP43,MSTN,GPM6B,GPR22,SOX21,IL6ST,PACRG,PDE1C,DUSP26,POU6F1,BCAS3,PTHLH,MARCH1,RAB3IL1,GAL3ST4,TTLL7,FERMT1,EPN2,SMTN,PALLD,TMCC1,DBNDD2,DOCK9,GPR161,KLC2,KCNK12,KCNAB1" Drug 2395_DN Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,AP2A2,ALAD,ARNTL,N4BP2L1,CCNT1,ARHGEF2,CDH10,RCHY1,SEC31B,CTIF,KIAA0753,SMG7,FEM1B,SIDT2,ABI2,SORBS3,IRAK4,ZNF589,ANKFY1,CINP,SEPT9,ZNF276,DHX35,NUCB1,OGDH,PIK3R1,NLE1,PLCB2,PPP3CB,MAPK3,GSTCD,RXRA,RASA3,ITSN1,RAB3GAP1,ZBTB43,CEP68,EXOC7,TCF7L2,DICER1,PIK3R5,RBFOX2,WIPF1,PRDM2,MPPE1" Drug 4948_UP Reserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AP2A2,SPARCL1,SYNJ2,CACNB2,LHX2,HOMER3,CNTN1,CSNK1E,MFAP3L,CDON,ATN1,EDNRA,SIDT2,RASGRP2,GAD1,GAD2,SRCAP,USP19,GLS,ICA1,IFI16,JAK2,KPNA5,VWA5A,MIA2,MOBP,RETREG1,PLTP,MTRF1L,PNMA8A,ASAP3,FUZ,SNAP25,KIF21B,ZHX3,ZC3H13,ZBTB43,POPDC3,WSCD1,ZEB1,TEX15,CABIN1,WIPF1,XRCC4,SLC17A7,MPPE1" Drug 3514_UP Lymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "KIAA1324,AMPD3,APLP1,DNAH17,CAMK2B,CCKBR,ARHGEF2,CLGN,PLEKHB1,SLIT2,ZFYVE9,ENTPD4,CSF1R,ARMCX2,FRY,TNK2,APC2,GABRA5,GAD1,SEPT9,RND1,GLS,LPAR4,GRK4,ICA1,KCNMA1,KIFC3,AFF1,MPP2,NF1,NOVA2,PLEC,RAB3IL1,SYNDIG1,MRAS,SLA,SMARCD3,ZCCHC24,AJAP1,WSCD1,CRTC1,UBTF,VAV2,WIPF1,CLIP2,ITM2C" Drug 2307_DN Trimethoprim [738-70-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABHD6,MTUS1,SRPX,MRTFA,SEMA7A,APC,ARRB1,CDK13,MARK4,CFLAR,C5,B4GALT6,SH2B1,DZIP3,SPATA2,SMG7,DSCAM,SUGP2,DMTN,ACSL4,TXNL4A,NR3C1,ELOVL5,MAP4,GIT1,NOS1,CNOT4,NRGN,NTRK2,PPP5C,PPP4R3A,BTBD7,MAPKBP1,ZHX3,CAMTA2,EXOC7,FBXW11,CRTC1,ATP13A2,CABIN1,CDK20,MICAL1,XRCC4,ZNF24,WNK1,EPM2A" Drug 2994_DN Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABHD6,SRPX,BIN1,CDC42BPA,ANK2,SLC4A4,ATP6V0A1,BACH1,CFLAR,SYNJ1,SCAPER,SGCE,CACNA1A,CACNB4,CLGN,RAB33A,CPS1,SIPA1L1,SLITRK5,SMG7,PLXNC1,RASGRP2,DLC1,FGFR1,GABRA4,SIGLEC8,GATM,ADAM28,GNAS,LILRA2,MAP4,PIK3CD,PROX1,TMEM231,TMEM206,MAP6D1,FRMPD1,SPTAN1,NSFL1C,ATP11A,PDLIM2,TCF7L2,TRO,KCNK12,REEP1,PARP11" Drug 1591_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADD2,CDC42BPA,ANK3,BMP7,CBFA2T2,COL9A2,SEC31B,CRYM,TM9SF4,C2CD2L,RCAN1,SIDT2,ABI2,SORBS3,RABEPK,ALDH1L1,SRCAP,GFER,GLYR1,GNG4,GRIK5,GSTM5,ITGAM,KLC1,MYO7A,NTRK3,SETD4,OGG1,RETREG1,KCTD15,PLCD1,POLG,RALGDS,PAQR6,ITSN1,AMBRA1,BCAN,FAM214B,WDTC1,DOK5,EMC1,RGL1,KCTD2,TNS1,ELP5,CAMK1G" Drug 1718_UP Phenindione [83-12-5]; Up 200; 18uM; HL60; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADD3,PLA2G6,BIN1,APBB2,APP,ARNTL,ARRB2,WASF1,CACNA1A,CNTN1,SLC4A7,SEC31B,TM9SF4,SGK2,SIDT2,ABI2,ANKMY1,SRCAP,CACFD1,NR3C1,ICA1,MARK3,TRHDE,RC3H2,LRP12,MBOAT7,SAMD9,GON4L,PTX3,RAB3GAP1,ELMO2,GSE1,NSFL1C,ATP11A,EXOC7,TBL1X,TCF4,ZNF34,SSBP2,FLRT2,NSD2,ZNF24,EVI5,SNX27,CAMK1G,ZNF248" Drug 3134_DN Pizotifen malate [5189-11-7]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MTUS1,APC,SLC4A4,ADAM23,BCL7A,EPS15L1,DNAJB5,CREM,SIPA1L1,CTNND1,SPOCK2,DCTN1,MAGI2,ERCC2,NBEA,GAA,GABRA4,GLS,SLC2A6,ELOVL5,ZNF862,NINJ2,CNOT4,P2RY1,PMP22,PRKCZ,MAPK7,MARCH1,ZDHHC14,SBF1,ST6GAL1,FAM214B,SNCA,EMC1,ARHGAP26,RAP1GAP2,MLC1,SYN2,TCF7,TCF7L2,PCDHGA10,BEST1,CLIP2,MKRN3,LAMP5,TIGD6" Drug 7348_DN Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASIC1,ALCAM,MRTFA,APLP1,MARK4,ATM,CFLAR,TAOK2,RAB28,ABCG1,CTNND2,KIAA0586,MFAP3L,C2CD2L,TMCC2,ATN1,HSD17B14,ANKMY1,SCML2,TESK2,FGFR1,SEMA4D,MSL3,GRB10,KCNH2,LMO2,MAP4,MATK,GIT1,ZNF862,NPR2,SERPINE2,MBOAT7,MAPK8,PRPH,RGS12,GSTCD,EPN2,ZKSCAN3,SZT2,BHLHB9,BEX4,REEP1,ST7,UBE3B,SMIM8" Drug 6602_DN Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "C1QTNF1,CDK13,ARHGEF1,SCARB1,CNOT8,DNAJB5,ABCG1,CSF1,PDE4DIP,SLITRK5,ARHGEF4,TBC1D5,DYNC1I1,PLEKHO1,COQ7,RRAGB,SEPT9,GBX2,GLRB,SCIN,LIG4,MAP4,MDFI,NFIX,PAK3,CCSER2,PRKAR1B,GON4L,RALGDS,FAT4,ZFP30,AMBRA1,BCAN,ANKRD6,SMARCD3,EMC1,ST5,SYT1,SMG6,SZT2,BEX4,NDRG4,NAV3,EPM2A,UBE3B,PHTF2" Drug 2645_UP Droperidol [548-73-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RALGAPA1,NME5,MRTFA,BEGAIN,APC,FAM131A,PPP4R4,ALDH4A1,SYNJ1,CACNA1D,RUNX1T1,DNAJB5,NCOR2,CHD5,CTIF,GIT2,C2CD2L,SNX29,ANKMY1,F5,FGF12,GFER,C1QL1,MALT1,GNG3,NXPH3,SCRG1,C2orf72,ITGA7,NOS1,GPR85,PLCD1,GSTCD,TCP11L1,IFT122,LIMCH1,IQSEC2,PLCB1,TAL1,SMG6,PCDHA6,SEZ6L,VAV2,WIPF1,TIGD6,SENP7" Drug 5332_UP N6-methyladenosine [1867-73-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABHD6,APBB2,APC,MARK4,ZBTB10,CA4,NCOR1,EDRF1,GIT2,DBN1,DTNA,PLEKHO1,RASGRP2,BAIAP2,ERAP1,AGBL5,TJAP1,KCNF1,LSS,TAGLN3,ZNF862,PDE4A,PRODH,PTN,FAM184A,BSDC1,CLIP1,RXRA,FUZ,PPP4R3A,BTBD7,SMARCC2,SNCA,ZHX3,EMC1,CLSTN2,TCF7L2,TRIM2,RPGRIP1L,DOCK9,BEX4,ZNF711,EVI5,MPPE1,MARCH8,PAK5" Drug 5300_UP Florfenicol [73231-34-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASPHD1,AMPD3,PDXK,ARHGDIG,ASPH,ALDH4A1,ALDH7A1,BTRC,CACNA1D,CRLF1,CSF1,PDE4DIP,CNTNAP2,DZIP3,DCAF8,INTS1,RABGAP1L,DLG3,SGK2,SIDT2,EGFR,TNK2,FHL1,GPR153,ATXN2L,ICA1,SSH1,PLCD1,PSMD13,ZSCAN32,RIPOR1,RAB3A,AMBRA1,ANKRD6,SLC9A5,TMCC1,DOK5,CEP68,ATP11A,TRIM2,CABIN1,WBP2,ZMYND8,SSBP2,ZNF24,EMSY" Drug 834_DN 5211181; Down 200; 12uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ALCAM,BIN1,SCAPER,LRRFIP1,QKI,ARHGEF6,CSNK1E,DCAF8,DTNA,DYRK1A,FCF1,ING4,MRNIP,MTSS1L,SCML2,ST3GAL6,FHL1,ANKFY1,CINP,FAM49B,ERAP1,SEPT9,POLL,GPER1,MAP4K5,MUM1,DHX35,CNOT4,SMIM7,STRN3,APTX,CEP97,RAD51D,SFPQ,BTBD7,POGZ,DIP2A,FAM208A,TMPO,METTL3,VGF,XRCC4,ZBTB14,ZNF45,UBE3B,TIGD6" Drug 4336_DN Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "PLA2G6,ALDH4A1,FOXN3,LHX2,HOMER3,CNTN1,SPOCK2,TRAPPC9,ATN1,HIPK3,FEM1B,EGFR,SORBS3,EPHA5,SORBS1,GABRA2,GNG3,STON1,GPER1,EML4,ITPKA,VWA5A,MBD1,SCAMP5,GIT1,CNOT4,NTRK2,NLE1,MINDY2,RGS10,IL17RB,LIMS2,KIF13A,ZNF415,DOK5,SPTB,LHPP,ASTN2,SMG6,TRIO,OSBP2,KLC2,SPHK2,TFIP11,KCNAB1,AAAS" Drug 2733_DN Methazolamide [554-57-4]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABHD6,AMT,CDC42BPA,APAF1,APBB2,MADD,NUMB,CD86,CLGN,CLCN4,QKI,KIAA0753,FCF1,COQ7,ERCC2,NCALD,ZNF589,KIAA1109,ANKFY1,PDLIM5,GNG4,LILRA2,ITGAM,LIG4,MEF2C,MIA2,NF1,NINJ2,PDE4A,CDK14,CCSER2,PLEC,RALGDS,CARF,SCG5,ZFP30,TROVE2,PLCB1,ATP11A,KIAA1107,KCTD2,PIK3R5,SMUG1,SSBP2,XRCC4,ZNF225" Drug 3247_DN Cefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "SRPX,MRTFA,DOC2A,GAS7,ADAM15,MPDZ,MAGI1,B4GALT6,RAB28,NMT2,QKI,SIPA1L1,DAPK3,DBT,MED12,RCAN1,TOM1,FCF1,EGFR,HSD17B14,EZH1,BAIAP2,FHL1,OGA,DISC1,SPACA9,KITLG,MPP2,GIT1,CNOT4,NLE1,PRKAR1B,ELOVL2,RGS12,MAPK12,RASA3,ELMO2,KDM4C,LHPP,MAPK8IP3,ANKRD12,EXOC7,CHST8,ZNF24,EMSY,EPM2A" Drug 1578_DN Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; HL60; HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ACTN2,NDRG3,AMPD2,AMT,APP,CFLAR,RAB29,HIP1R,EPS15L1,PREPL,CREM,HINFP,NCOR1,PUM1,RUBCN,CYBB,ZNF337,TM9SF4,SMG7,CEND1,C1orf61,ZNF44,PRRC2B,NACA,NF1,SLC11A2,PDE4A,EXOSC10,MAPK10,TMEM231,DPF2,GSTCD,PCMTD2,NEK11,CCDC88A,SLN,SMARCA4,CDK5RAP2,SNAP25,GANAB,MMS19,TCF4,TPM1,METTL3,ZNF189,ADAMTS9" Drug 5767_DN Retinoic acid [302-79-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "CDC42BPA,CDK10,ALDH4A1,ATP2B1,CLU,DNAJB5,CSF1R,PDE4DIP,SDC3,APPL1,SNPH,SGSM2,DLG3,SIDT2,EML1,PLEKHO1,SCML2,SCARA3,DISC1,PCDH17,SHISAL1,TJAP1,INPP5B,NUMA1,PCDH9,PLCD1,PPP5C,PRPH,RIPOR1,FAM184A,ROGDI,ATXN1,ATXN7,ZNF821,ZFP30,ASAP3,SLC14A1,TMCC1,KDM4C,ST5,PLCB1,SYT1,ATP11A,TCF4,CABIN1,TRPC1" Drug 7345_DN Alcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AP2A2,CA12,SRSF11,QKI,AKAP7,ABCG1,DZIP3,PPP6R2,USP6NL,EDRF1,DBT,HP1BP3,SIDT2,PHF20L1,EIF5,ENO2,STX2,ANKMY1,GPR153,TXNL4A,MSL3,KCNMB4,HNMT,ITPKB,MAPT,KITLG,MKLN1,ZNF862,NFYA,NRGN,PDE4A,RETREG1,ELOVL2,PTPRE,RGS10,MYH14,NEK11,ITSN1,EPN2,WDTC1,ZSWIM8,DIP2A,STX1A,NSFL1C,TRIM2,GAN" Drug 882_DN ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "CLK4,ADD3,ZBTB10,MPDZ,RAB29,USP6NL,DAPK3,HP1BP3,G3BP2,RBM12,TESK2,FGFR3,CELF1,ZNF44,FERMT2,PRRC2B,GPD2,GPR19,BRINP3,DIPK1A,JAK2,MBP,NAP1L2,PIK3R1,CCSER2,RC3H2,RIPOR1,RDX,AP1AR,HSPA4L,FUZ,URGCP,PPP4R3A,KBTBD4,SLC15A2,SMARCC2,CDK19,WWC1,DICER1,NACC2,TMPO,RBFOX2,UBE3A,UBTF,NSD2,FZD3" Drug 4758_UP 0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RALGAPA1,AP2A2,LTBP4,APOC1,CDC14B,SEMA4G,MARK4,PTCH2,RGS9,SCAPER,DNAJB5,GREB1,DBT,RHOBTB1,SPOCK3,DMPK,DTNA,EDN1,EDNRA,EPHB1,ERBB4,OGA,KCNH2,KCNJ5,SMAD1,NDUFA5,NEUROD1,SETD4,PLCD1,LRP12,PTHLH,RAB3IL1,TCP11L1,RPS6KA2,EMID1,CPEB3,CNKSR2,SNCA,KDM4B,ZCCHC24,SYN2,SYT5,LAT2,KCNK12,XRCC4,SLC30A4" Drug 3566_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,CDC42BPA,APBB2,RIPK1,CFLAR,SULT4A1,PDE4DIP,GIT2,MFAP3L,EDNRA,EML1,EZH1,SYT17,PRRC2B,ICA1,KHK,MAP4,NPR2,PDE3B,PPP3CC,PRKAR1B,PTPRE,NKAIN1,ATG16L1,RGS10,SH3BP2,EPN2,SMTN,SLC6A8,CCDC88A,LIMCH1,ZCCHC24,ZHX3,THSD1,MAPK8IP3,TTBK2,SMG6,TCF7L2,RPGRIP1L,ATP13A2,TK2,CABIN1,RPRM,LMF1,ZBTB14,GAN" Drug 6226_DN "Eserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "OSBPL1A,CDC42BPA,MTMR2,PTBP2,KRIT1,SCARB1,SYNGR3,SRSF11,COL4A5,SMARCAL1,FEZ1,DCAF8,GIT2,EXOG,DNM2,MRNIP,EFEMP1,SEMA4D,TRMO,MALT1,EML4,IL6ST,MAPT,MIA2,GIT1,NFYA,PDE4A,PMP22,MBOAT7,TMEM231,RAB3IL1,ARID4A,BSDC1,RPS6KA2,BTBD3,RAB3GAP1,MAPKBP1,POGZ,SS18,CEP68,MCF2L,TCF7L2,BEX4,DNAJC12,FTSJ1,ACTR3B" Drug 5747_DN Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASIC1,AP2A2,CDC14B,ADAM15,SCAPER,BTRC,FOXN3,ASIC3,CHM,B4GALT6,RAB28,CLCN4,CRY2,CSNK1E,SLITRK5,GIT2,SMG7,CDON,EIF4G2,EPHA5,FGFR1,CGREF1,TRAF3IP2,GNG4,MUM1,HSF2,L1CAM,MDFI,SCAMP5,RETREG1,PTPRN2,PID1,RAD51D,SEC61A2,ZNF671,MAPK12,SBF1,SNCA,KDM4C,PHLDB1,KIAA0930,CHST8,VGF,ZNF32,NAV3,MPPE1" Drug 4829_DN Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADCY6,CDK10,ARRB2,ARHGEF7,NCOR1,SOCS5,APPL1,ARHGEF4,GPRASP1,ARHGAP32,DBT,HP1BP3,MED12,TRAPPC9,DTNA,SUGP2,TNK2,DENND4A,ANKMY1,EZH1,FGFR1,CGREF1,INPP5K,ZNF276,GPR37,MPP2,SETD4,ODF2,PCDH9,PLEC,PPP5C,PRODH,RAB5B,BSDC1,RGS10,DCUN1D2,ABLIM3,SMTN,SLC20A2,TMCC1,ZBTB43,TACC1,SEMA4A,BEX4,VGF,HPS4" Drug 3484_UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "SPARCL1,ALCAM,TRMT9B,APOC1,MARK4,ABCG1,DCAF8,EFNA3,SORBS3,ERCC2,FOXG1,DCTN2,DPYSL4,DLL3,STON1,ELOVL5,TJAP1,INPP5B,KCNH2,MAP4,ZNF862,PDE4B,PDGFRA,SMOX,VPS13C,FAM184A,ZDHHC14,RGS12,SH3BP2,PPP1R9A,SMTN,BTBD7,ZCCHC24,SPTAN1,ST5,POPDC3,KAZN,MTCL1,EXOC7,SMG6,KIAA0930,CRTC1,AMACR,VGF,XRCC4,KCNAB1" Drug 1542_UP Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NME5,CDC42BPA,CDC14B,MARK4,SYNJ2,CAMK2B,CBFA2T2,SLIT2,DNAJB5,WHRN,RIMS2,KIAA0586,SPOCK2,DNAJC6,MFAP3L,KBTBD11,IGSF6,FOXG1,PRELID3A,POLL,NR3C1,MUM1,IL6ST,INPP5B,LMO2,ZNF862,NPY,PC,TNPO2,PPP5C,PRODH,GDPD2,PTHLH,ZSCAN2,ASAP3,SLC2A5,COA1,RBM34,INKA2,STX1A,AJAP1,KIAA1107,TRIM2,SZT2,CRTC1,UPF3A" Drug 2328_DN Fludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADRA1D,BIN1,SEMA7A,ATM,BAIAP3,HAP1,ARHGEF2,LY86,SDC3,NOS1AP,RIMS3,ATN1,EIF4G2,C3orf18,FHL1,FOXG1,PDLIM5,TRAF3IP2,HBS1L,SRCAP,ADAM28,C1QL1,TXNL4A,GPER1,GRM7,TJAP1,MBD1,MOBP,NEK1,CDK14,MAPK7,GTDC1,RPS6KA2,FRMPD1,PPP4R3A,BTBD7,SLN,EMC1,ARHGAP26,ELOVL4,STX1A,ROBO3,DICER1,ZMYND8,XRCC4,ZIC3" Drug 2187_DN Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RALGAPA1,ABAT,PLA2G6,MRTFA,PPP4R4,ASPH,NUMB,ATP2A2,CACNA1A,CAMK2G,TAOK2,COL9A2,CSNK1E,PPP1R16B,ZFYVE16,RASGRP2,ZNF589,CSPG5,CRCP,LILRA2,GPR22,GRIK5,SLC2A6,SLC11A2,MAPK7,CNTLN,RAB3A,TCP11L1,SH3BP2,PPP4R3A,ELMO2,SNCA,TMCC1,CAND2,ZC4H2,MAPK8IP3,VAMP1,KIAA1107,TCF7L2,PCDHGA10,OBSL1,R3HDM1,PIK3R5,ZKSCAN5,WIPF2,TIGD6" Drug 6061_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASPHD1,ADCY2,PLA2G6,SEMA7A,APAF1,APC,SEMA4G,CFAP410,HAP1,ARHGEF2,SEPT7,CHRNB2,ZFYVE9,TPP1,LY86,RCHY1,CRMP1,CSF1,FEZ1,FAM169A,GREB1,SEC14L5,EDNRB,HIPK3,EN2,DLC1,FHL1,GAD1,GLYR1,GPD2,GRM1,KCNH2,ADAM22,RETREG1,POLG,RGS10,TCP11L1,SBF1,TROVE2,VAMP1,PLCB1,EXOC7,PDLIM2,XRCC4,SSPN,DPF3" Drug 3272_DN SR-95639A [115767-94-7]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,AMPD2,GAS7,APLP1,FAM131A,MPDZ,SCAPER,MAP4K4,MAML1,KBTBD11,GNE,LRRC23,FGFR3,NOP56,CGREF1,GLUL,POLL,TDRKH,IGSF1,KCNF1,KCNJ3,LSS,MAP4,MPP2,NUMA1,SETD4,PDE4A,CCSER2,SLC25A23,POLG,ZCWPW1,RGS12,ROM1,WLS,SBF1,ABLIM3,PEX26,SMTN,SOX3,FNBP1,EMC1,SPTAN1,ATP11A,PCDHA6,SIK3,VAV2" Drug 2275_DN Nimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,AMPD3,APBA2,APBB2,PPP4R4,DNAH17,CADM3,GYG2,CAMK2B,PLEKHB1,SLIT2,HOMER3,CNTN1,SDC3,HP1BP3,DTNA,DMTN,TRMO,HBS1L,SRCAP,POLL,GNG3,CACFD1,ITPKB,KCNN2,VWA5A,ZNF862,SLC11A2,CDK18,PLCD1,ZDHHC14,RGS3,KLHDC8A,WLS,ZNF821,ABLIM3,SMARCD3,RBM34,TCF7L2,VGF,MICAL1,SPHK2,REEP1,DNALI1,GDPD5,JPH3" Drug 7046_UP PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AP2A2,BIN1,CDK10,CAMK2B,PLAA,QKI,CNTFR,DZIP3,RIMS2,SIDT2,CELSR3,SORBS3,ING4,ZNF589,FER,FOXG1,SORBS1,HBS1L,USP19,MSL3,SHISAL1,MX1,PALM,POLG,PRKAR1B,PTAFR,PTCH1,GAL3ST4,RPS6KA2,ZNF821,DOCK10,SLC9A5,KDM4C,ARHGAP26,EXOC7,SMG6,TIMP4,TNS1,FAM155A,EIF4ENIF1,NSD2,REEP1,NT5M,EPM2A,SMIM8,TIGD6" Drug 7264_UP Clorsulon [60200-06-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADCY6,ALK,KCNAB2,APC,APP,ARRB2,BID,MTMR2,WASF1,CHM,RAB28,ZFYVE9,CSF1,ARHGAP24,GIT2,EGFR,IRAK4,PCOLCE2,COQ7,F3,TESK2,CAMSAP1,ZNF274,NCKAP1,GLI2,GLS,HSF2,LIG4,LSS,NF1,MAPK7,GTDC1,AP1AR,AMBRA1,CHD9,PEX26,ZNF334,TMCC1,TROVE2,NXT2,SYT1,ATP11A,TRPS1,HIRA,EMSY,PHTF2" Drug 6311_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "SHROOM2,BRINP2,NRP2,SCAPER,CBFA2T2,FADS2,ABCG1,SGSM2,EFNA3,IRAK4,FGFR1,PNMA2,DISC1,KCNMB4,GPM6B,GPR17,NR3C1,ATXN2L,SYNPO,HNMT,HSF2,KIFC3,SMAD1,MIA2,MMP16,NOVA1,PFKFB2,DUSP26,PTCH1,RAB3A,SUGCT,NCBP3,FBXO11,WDR37,ARHGEF40,BTBD7,SLN,KIF13A,ST5,PHLDB1,FBXW11,SMG6,NT5M,KCNAB1,PHTF2,NUP214" Drug 2565_DN Glycopyrrolate [596-51-0]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MRTFA,TRMT9B,APC,CDC14B,SLC4A4,N4BP2L1,SYNJ2,LDLRAD4,CACNB2,CAPN3,RAB33A,TPP1,CPS1,VCAN,PPP1R16B,ZNF337,CDON,DTNA,TOM1,FEM1B,MTSS1L,PIPOX,DLC1,GABRA4,MAP4,MEF2C,N6AMT1,CNOT4,RETREG1,PLTP,PMP22,MAPK7,RIPOR1,FOXRED2,CNKSR2,MAPKBP1,CEP68,RGL1,CRTC1,TMOD1,TNNT1,TPD52,LMF1,XRCC4,ZNF32,STMN4" Drug 4127_DN Sulmazole [73384-60-8]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADORA2A,KIDINS220,LTBP4,SEMA7A,PDE8B,MARK4,CAMK2B,CBFA2T2,SCARB1,CRMP1,ARHGEF10,NOS1AP,CYBB,RASSF2,RIMS3,HP1BP3,DSCAM,EDN1,EFNA3,ING4,LRRC23,ERCC2,VPS26C,ZNF589,FHL1,DISC1,GPM6B,GRIK5,GRM8,HLF,IL11RA,KCND3,AFF1,NNAT,NLE1,CARF,TCP11L1,SH3GL3,BTBD7,SNAP25,SNCA,CLSTN2,AJAP1,TBCEL,ZEB1,PCDHGB6" Drug 3389_DN Bemegride [64-65-3]; Down 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "SEMA6A,BIN1,APC,PPP4R4,PDE8B,MTMR3,CAMK2B,ADGRG1,LHX2,STOML1,CSF1,NOS1AP,MFAP3L,HP1BP3,RABGAP1L,DMPK,VPS13B,NCALD,CAMSAP1,ALDH1L1,TDRKH,ELOVL5,KCNN2,TM6SF1,MDM4,ADAM22,GPR85,SERPINE2,NLE1,PLCD1,MED1,MINDY2,MAPK10,RAB3A,RAB3IL1,RASA3,PPP1R9A,ASAP3,FNDC3A,PPP4R3A,PKNOX2,SNCA,DOK5,EMC1,CABIN1,WIPF1" Drug 5343_DN Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ALAD,CDK10,ATM,UBE2L6,SOCS6,VAX2,HOMER3,CREM,ENTPD4,AKAP12,DLG3,MED12,RGS17,PLEKHO1,GPR153,GLS,GPR37,NR3C1,BTN2A1,ICA1,DIPK1A,MAP4,NRGN,NUCB1,RC3H2,TMEM231,MAP6D1,PAQR6,MAPK12,SGK1,SMTN,EFHD1,SMARCA4,KDM4C,CLASP2,SS18,ELOVL4,TCF7,TIAM1,KCTD2,PARD3,CABIN1,ZMYND8,VAV1,SF1,MAP3K12" Drug 3411_DN Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AP2A2,ALCAM,NCOA1,NUMB,ATP2A2,BCL7A,CCNT1,FOXN3,TAOK2,ZFYVE9,CLCN3,QKI,LRIG1,SOCS5,PDE4DIP,GPRASP1,LYPD1,SMG7,SIDT2,ZNF44,SYT17,INPP5K,PRRC2B,KIF3A,IL6ST,MAPT,PIK3R1,MBOAT7,PRKAR1B,PRPH,ZCWPW1,SLC25A36,FAM192A,SH3BP2,ITSN1,EPN2,PBLD,MAPK8IP3,ELOVL4,TCF7,TCF7L2,ZNF384,UBE3A,SF1,UPF3A,MVB12B" Drug 2387_DN Glafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG3,ADRB2,ALK,MARCH3,SLC4A4,ATP2B1,RIPK1,CAPN3,CCNT1,SCARB1,CDH10,ARHGEF10,CTIF,KIAA0753,SORBS3,COQ7,PCYOX1,GAD2,SEPT9,WASF3,ALDH1L1,INPP5B,ITGAM,LSS,MAPK8,PEX5,RAD52,TCP11L1,PAQR6,RASA3,HSPA4L,COA1,SPP1,DDN,MAPK8IP3,STXBP1,WWC1,TCF7L2,HIF3A,THRA,TK2,RBFOX2,ZKSCAN5,ZBTB14,LAMP5,MPPE1" Drug 6737_DN Ethaverine hydrochloride [985-13-7]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADRB2,MTUS1,MRTFA,BIN1,CDK10,PDE8B,ATP1A3,ATP2A2,KIF1A,CAMK2B,AKAP7,NRG2,NCOR2,ARHGEF10,HDAC9,ATN1,MRNIP,HSD17B14,SPEG,DLC1,ST3GAL6,TESK2,GPER1,INPP5B,KPNA5,LIG4,MYT1,NF1,NFIX,SLC11A2,PTN,RIPOR1,TMEM156,FOXRED2,SBF1,SLC14A1,TMCC1,SYT11,SUPT5H,SYT1,WWC1,PCDHA5,TNS1,VIPR2,KCNAB1,ACTR3B" Drug 2379_DN Trazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "BRAP,ALK,MRTFA,KCNAB2,APP,N4BP2L1,ADAM15,ARHGEF7,MAP7,QKI,IQCK,SH2B1,VCAN,RUBCN,SMG7,E2F5,TSPAN5,VPS26C,ANKMY1,ZNF589,TXNL4A,EML4,DHX35,MAP4,NFYA,PDE4B,PIK3CD,PIK3R1,PTPA,RAB3IL1,RALGDS,GSTCD,RASA3,ITSN1,FAM102A,ARHGAP26,DBNDD2,DDN,COLGALT2,STXBP1,SYT11,EXOC7,CAMSAP2,TCF4,HIF3A,ZNF45" Drug 1042_UP "aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADD3,CDC42BPA,CDC14B,ARRB1,ARHGEF7,KYAT1,RAB28,QKI,ABCG1,DCAF8,GIT2,DBT,C2CD2L,LYPD1,SGSM2,ABI2,KIAA1109,CGREF1,GART,GLYR1,GRB10,MAP4K5,HSF2,KCNK1,KHK,SETD4,PDE3B,CCSER2,STRN3,SYTL2,SLC25A36,TCP11L1,SHANK2,BTBD7,ZSWIM8,KDM4C,CDK19,ZBTB43,ELOVL4,TACC1,DNMBP,TCF7,TRIM2,KCTD2,ZNF384,ZNF24" Drug 3466_UP Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBA2,ARHGDIG,CFLAR,GYG2,CACNG1,HIP1R,PLEKHB1,CHRNB2,IQCK,COL9A2,SLC4A8,SH2B1,ARNT2,EXOG,GNE,SIDT2,ELN,ZNF589,FOXG1,DPYSL4,GPER1,IL6ST,ITPKB,KPNA5,MATK,PLCB2,PMP22,RAD52,FAM184A,RGS12,EMID1,SH3BP2,ASAP3,SMARCD3,ZHX3,PHLDB1,VPS13A,PLCB1,EXOC7,PCDHA6,CHST8,ZNF34,SLC44A1,SF1,GDPD5,EPM2A" Drug 4119_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RGS20,SGCE,AATK,CSF1,CSF1R,ELMO1,DYRK1A,FCF1,ELAVL2,KIAA1109,GAB1,GABRA2,GAD1,RUNDC3A,GPM6B,GRIK2,GRM7,ICA1,MAP2,MMP16,ADAM22,CDK18,PDE4B,PLCD1,LRRN3,MAPK7,DCHS2,ZMAT4,GSTCD,RASA3,SH3BP2,PPP1R9A,SH3GL3,SLC11A1,HECW1,ARHGAP26,NXT2,INKA2,KIAA1107,DMXL2,CRTC1,TMOD1,TPM2,VSNL1,ITM2C,SSPN" Drug 4708_UP Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AMPD3,N4BP2L1,CFLAR,RUNX1T1,CLGN,QKI,RCHY1,DBT,ARMCX2,EXOG,TRAPPC9,EDN1,EFNA3,EFNB3,EN2,IGSF6,RRAGB,OLFM1,FGFR1,FHL1,GALC,GAP43,GCNT2,GRIK5,NR3C1,TJAP1,KCNJ3,KIFC3,MID1,ADAM22,NTRK2,CDK18,SERPINE2,PTHLH,PTK2,TMEM231,C1orf54,TTLL7,CARF,ROM1,WLS,SYT5,PCDHA6,TRPM2,PLSCR4,SSPN" Drug 204_UP sulfasalazine; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,BIN1,GAS7,AQP6,ASCL1,BTRC,CANX,CH25H,NEURL1,ARHGAP33,SLC4A7,NCOR1,AATK,DZIP3,ARHGAP32,ATN1,EFNB3,CEND1,F5,FHL1,AGAP2,GRIN1,NR3C1,PADI2,ITIH2,KCND3,NFYA,PAK3,PBX1,PFKFB4,PRPH,RAD51D,CCDC25,ZNF331,SEMA6D,FRMPD1,ASAP3,SLC1A2,WDTC1,ZCCHC24,SYT5,ZMYND8,TSN,CADM1,CLIP2,MARCH8" Drug 2664_UP "aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "MTUS1,APAF1,PPFIA3,PPP4R4,CASK,ALDH4A1,SCARB1,RAB33A,SLC4A8,CREM,CNTNAP2,DZIP3,USP6NL,ZNF337,DAPK3,HIPK3,RRAGB,FGFR1,FHL1,PDLIM5,PRELID3A,GALC,ALDH1L1,LILRA2,STON1,GRIK5,SYNPO,IL6ST,KCNMA1,NPTX1,NUMA1,OXTR,PPARA,CRTAC1,EMID1,RPS20,RYR1,SLC8A2,TMCC1,ACSBG1,TACR1,CUX2,TRPC1,TRPS1,PRDM10,SLC17A7" Drug 3442_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBB2,APC,PPFIA3,ARRB2,CDK13,ALDH4A1,SYNJ2,LDLRAD4,HOMER3,GREB1,DCAF8,RCAN1,EGFR,AGAP2,FAM49B,INPP5K,GART,GCNT2,POLL,GPD2,GSN,KCNJ3,KHK,MAP4,MBD1,KITLG,MYO6,NUCB1,CDK18,PDE3B,GPR85,PLEC,SLC25A23,PTN,RAB3IL1,RGS12,TCP11L1,FOXRED2,ANKRD6,SPART,CEP68,AHCYL2,CLDND1,ZNF24,NT5M,EPM2A" Drug 7415_UP Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "APBB2,PPFIA3,ALDH4A1,ATP2B1,MTMR9,CAMK2B,CAMK2G,CHRNB2,ENTPD4,SH2B1,CTNND2,NR1D2,HIPK3,OPTN,LRRC23,ACSL4,FGFR1,INPP5K,POLL,GNG4,SPACA9,VWA5A,MBD1,AFF1,NF1,CNOT4,NTRK2,NUMA1,MBOAT7,LRRN3,GSTCD,MAPK12,SLC1A7,WDTC1,ZC3H13,ARHGAP26,PLCB1,POPDC3,ATP11A,EXOC7,AGTPBP1,TRIM2,VLDLR,ZNF45,GDPD5,SSPN" Drug 464_UP WY-14643; Up 200; 100uM; PC3; HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ABAT,ABHD6,AMT,EPB41L5,CASK,SLC4A4,CACNA1I,CALB2,CDH18,CHGB,SLC24A2,LY86,NCOR1,HS3ST2,ANKMY1,RASL12,CEND1,EXTL2,FKTN,KIAA1109,ZNF44,AFF1,ADAM22,NTRK2,PMS2,CEP41,PTAFR,ACSS3,RALGDS,RET,RGS4,RGS12,MYH14,FAM214B,BEX1,TSPYL2,ATP10B,FCHO1,VAMP1,DMXL2,SEZ6L,BCL2L13,REEP1,WNK1,PRDM2,NUP214" Drug 7412_UP Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "BIN1,APBB2,GAS7,ALDH4A1,CFLAR,MTMR3,ARHGEF2,REPS2,CHN2,CREB5,CSNK1E,KIAA0586,DNAJC6,EFNA3,MRNIP,ERCC2,ACSL4,ZNF589,FAM49B,SYT17,POLL,RASSF8,KCNH2,NPTX1,NUMA1,SETD4,ZSCAN32,RGS12,ZFHX4,SLC1A7,SNCA,RBM34,FNBP1,ZSWIM8,RAP1GAP2,INKA2,PHLDB1,ASTN2,ATP11A,TACC1,TRPM2,VLDLR,MAP3K12,STMN4,HPS4,MVB12B" Drug 4730_DN Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,SLC12A5,C1QTNF3,MRTFA,GAS7,MADD,MARK4,REPS2,DAPK3,JAKMIP2,PARD6A,EFNA3,EFNB3,HSD17B14,LRRC23,NCALD,RRAGB,AFF2,SRCAP,MSL3,STON1,SLC2A6,ATXN2L,MAP4,MMP16,MSI1,NF1,PDE3B,PIK3R1,NLE1,LRP12,ZSCAN32,RAD52,RGS3,SELL,PREX2,SMARCD3,WDTC1,ZNF423,CLSTN2,MAPK8IP3,TRIM2,TNS2,TMEM121,KCTD2,ZNF45" Drug 6936_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,ADORA2A,AP2A2,AMH,ARHGDIG,SCAPER,CACNA1D,SCARB1,CDH2,PICK1,CREM,ENTPD4,AKAP12,ABCG1,MICAL2,ARHGEF4,PPP6R2,NOS1AP,RUSC2,ATN1,EDNRA,RASGRP2,F3,FECH,OGA,GLS,GPM6A,GRB10,NR3C1,HSD17B1,MARK1,ZNF862,PLTP,CCDC92,ABLIM3,SLC6A9,KDM4B,WDTC1,ZHX3,VAMP1,TACC1,TMOD1,PARD3,NPL,METTL3,PLPPR2" Drug 6865_UP SC-560; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ACLY,PLA2G6,RCBTB2,TAOK2,SH2B1,CTNND2,DAPK3,LPAR6,REEP2,PTK2B,KIAA1109,FGFR1,FHL1,MPP6,GBX2,GPR37,CNTRL,KCNN1,KHK,MAP2,NDP,NF1,ODF2,PDE4A,PDPK1,EPN1,FSD1,MINDY2,PRKAR1B,MAPK7,SAMD9,SYTL2,C1orf54,SBF1,HSPA4L,SOX15,AHCYL2,TF,BEX4,RBFOX2,SEZ6L,TPM2,TRIO,VIPR2,WNT7A,RNF146" Drug 2698_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "C3orf14,SEMA7A,ASPH,ATP1A2,BMP7,CDH10,GPR37L1,CHGA,CHI3L2,SULT4A1,SLC4A8,HAPLN1,ARHGEF10,SIPA1L1,PDE4DIP,USP6NL,EDN3,HIPK3,DLC1,PDLIM5,GABRA2,GJB1,STMN2,TPPP,GUCY1A1,KLF12,HTR2A,KCNA2,KCND3,KCNF1,MOBP,NCAM1,PTH1R,ZSCAN32,NEK11,SMTN,SYN2,SYT5,TCF7L2,PHF24,PSD3,ICAM5,TNS1,ZNF225,EVI5,STMN4" Drug 5326_DN Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "KIDINS220,EP400,APAF1,PPFIA3,NUMB,ALDH4A1,MPDZ,BMP7,SYNJ2,C5,OSGIN2,KRIT1,ARHGEF2,REPS2,HOMER3,CTNND2,DNAJC6,RBM12,PCOLCE2,EPB41L2,FGFR3,BAIAP2,PRKAG2,GAA,INPP5K,GOLGB1,KHK,MBP,MEIS2,NUCB1,PTK2,AP1AR,FERMT1,FBXO11,RCOR3,SPATA7,ZSWIM8,TSPYL2,NXT2,KANK1,TCF7,TCF7L2,TRIM2,FRYL,KAT6B,TRIO" Drug 7177_UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "AK2,PLA2G6,C1QTNF3,APC,SEMA4G,ARNTL,CADM3,CFLAR,SCAPER,CACNA1A,KYAT1,CDC27,MAGI1,QKI,AKAP7,SLC4A8,HP1BP3,LYPD1,SPOCK3,DSCAM,EFNA3,EGFR,MBNL2,HSD17B14,CDKL3,CAMSAP1,HTATSF1,GNAS,GRB10,GRM1,RELN,GTDC1,ZFHX4,ZHX3,SPTAN1,IQSEC2,PLCB1,SEMA4A,OBSL1,PCDHA6,AP4E1,PIK3R5,TPD52,TRIO,ZMYND8,NUP214" Drug 6094_UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ACTN2,GRAMD1B,BIN1,SEMA7A,LDLRAD4,DNAJB5,CSF1,DGKG,ATN1,ELAVL3,ELAVL4,ELN,RASGRP2,SPEG,PIPOX,FOXG1,DPYSL4,HBS1L,ATP8A2,PRUNE2,GPER1,NR3C1,GRM7,IL6ST,KCNH2,KHK,MMP17,BCO1,ENPP2,PGAM2,PPARA,PPP1R1A,SAMD9,RGS12,SH3BP2,ASAP3,RPH3A,RGL1,PHLDB1,ATP11A,CRTC1,TIMP4,SEZ6L,PRMT8,KCNK12,PAK5" Drug 3459_UP "Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "NDRG2,AMT,ARHGDIG,RGS20,ALDH4A1,ATP6V0A1,SCAPER,CAMK2B,CACNA2D2,CNOT8,STOML1,ENTPD4,SIPA1L1,EDRF1,EGFR,NCALD,BAIAP2,IQCG,TPK1,POLL,TJAP1,INPP5B,JAK2,KIT,MAP4,ADAM22,ZNF862,NF1,ZDHHC14,GTDC1,TCP11L1,ZNF821,SUPT20H,SLC1A7,PEX26,SHANK2,CXXC4,TMCC1,ZHX3,MAPK8IP3,ARC,CHST8,TRIO,VGF,LAT2,WIPF2" Drug 3457_UP Hecogenin [467-55-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADORA1,AP2A2,AK2,ARHGDIG,MARK4,KSR1,MTMR7,CLCN4,COL9A3,SIPA1L1,ARHGEF4,NOS1AP,CTIF,KLHL3,EXOG,C3orf18,FGFR1,SCARA3,GABRA2,PCDH17,STON1,GRM1,GSTM5,MAPT,POU3F4,LRRN3,PPP5C,PRODH,PTAFR,RAD52,RGS3,RGS4,ROBO1,ASAP3,PREX2,SMTN,SNCA,KDM4C,INKA2,AJAP1,EXOC7,KIAA0930,DICER1,OSBP2,REEP1,EMSY" Drug 435_DN "novobiocin sodium, USP; Down 200; 100uM; PC3; HG-U133A" Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "RBM10,ADD2,AMT,APAF1,ASCL1,HIP1R,CACNA2D2,CHN1,CHRNB2,CLCN4,NRXN1,GIT2,HP1BP3,FEM1B,ELAVL2,RGS17,SRPK3,VPS26C,ATP6V1H,FYN,B4GALNT1,IRF8,KTN1,MAP4,MAPT,MGAT3,GIT1,MYL3,NLE1,PLCD1,PNMA3,MBOAT7,PTPRN2,NUDT11,PAQR6,RXRA,ATXN2,ITSN1,MAPKBP1,SRPK2,ZFR2,SEMA4A,CRB1,NSD2,ZBTB14,ZNF142" Drug 1857_DN Sulindac [38194-50-2]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ADORA2A,GAS7,APP,N4BP2L1,BCL2L2,BCL7A,KRIT1,CNOT8,HOMER3,CREM,CRY2,PPP1R16B,DOCK4,SMG7,DTNA,FAM13A,PLXNC1,PTK2B,FECH,CINP,OGA,TRAF3IP2,GART,MSL3,SLC2A6,HSF2,IRF8,ITGAM,ZNF862,NAP1L1,SERPINE2,PPP3CB,SCP2,FERMT1,ZKSCAN3,SP2,MAPK8IP3,TTBK2,EXOC7,RBFOX2,METTL3,ZMYND8,PLPPR2,XRCC4,EPM2A,PHTF2" Drug 5314_UP Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "C1QTNF3,SRPX,ASPH,ALDH4A1,ATM,SCAPER,QKI,PICK1,CNTN1,SH2B1,PDE4DIP,ZNF804A,RABGAP1L,DTNA,FEM1B,SORBS3,DENND4A,F3,ATP2C1,GFER,GLS,POLL,DHX35,MAP4,GIT1,ADAM22,PDE3B,LRP12,PPP2R2B,PRKAR1B,C1orf54,GTDC1,RGS12,DCUN1D2,ROBO1,ROM1,TCP11L1,FOXRED2,WDTC1,NXT2,PJA1,TCF7,CABIN1,ZBTB14,UPF3A,NUP214" Drug 3752_DN Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.20E-03 1.00E+00 1.85E-02 2.11E-01 46 197 "ASIC1,ANK3,APBA2,NEURL1,LHX2,VCAN,CNTNAP2,STX2,CORO2B,FCGRT,FGF1,SCARA3,DISC1,GFER,GPR19,INPP5B,JAK2,IPO5,SCAMP5,ZNF862,ODF2,PDE4D,RETREG1,ASAP3,FNDC3A,DZIP1,KDM4D,ELMO2,SMARCA4,RBM34,ATP10B,EXOC7,KIAA0930,ZEB1,TNS2,TIAM1,CBX5,TMPO,TNS1,TPM1,CDK20,CADM1,PLPPR2,LMF1,WNK1,TIGD6" Drug CID000003804 Prestwick_517 Stitch 3.21E-03 1.00E+00 1.85E-02 2.11E-01 28 106 "FZD9,C1QTNF3,DDR1,NRG2,CSF1R,APPL1,SIRPA,DLG4,EXOG,EGFR,ERBB2,ERBB4,FGFR1,FGFR3,NRG3,STAG2,MALT1,KCNJ4,KIT,PDGFRA,SERPINE2,SMOX,PTCH1,PTPRN,PTPRN2,SLC14A1,TMEM132D,FIP1L1" Drug CID000005263 lysosphingomyelin Stitch 3.23E-03 1.00E+00 1.87E-02 2.12E-01 39 161 "ANK1,CDR1,PLCXD3,ENPP6,B3GAT1,GALC,GPR12,LPAR4,PLCD4,GPR45,KCNJ3,KCNJ5,KIT,ASPRV1,KITLG,MITF,P2RX7,ENPP2,PLCB2,PLCD1,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTAFR,FBXW7,ACER3,RYR1,RYR3,MAPK12,SMPD3,FNDC3A,PLCB1,TACR1,PLD4" Drug CID000001316 dimethylphenylpiperazinium Stitch 3.23E-03 1.00E+00 1.87E-02 2.12E-01 18 59 "ACHE,ADORA1,ADORA2A,ADORA3,BCHE,CHRM1,CHRNA4,CHRNB2,DMPK,BCO1,NPY,PDCD2,PDE1C,PDE1B,PENK,PEG10,SST,TAC1" Drug CID000001117 sulfate Stitch 3.25E-03 1.00E+00 1.88E-02 2.14E-01 239 1293 "SERPINA3,SYN3,ACHE,AP2A1,AP2A2,ALK,AMT,PDXK,ARHGDIA,ARSE,ARSF,CHID1,ATP2A2,BARD1,BCHE,FGF17,GPC2,CA4,CACNA2D1,CACNG1,CALM1,NGB,CBR1,CBS,KYAT1,CCK,SCARB1,CD38,ENTPD2,CDC42,DCLK1,CDO1,NUMBL,CFL2,CHRM1,CHRNA4,CHRNB2,NDST3,SLIT2,SLC22A6,TPP1,MYL6B,FBXO7,ABCG2,SULT4A1,COL4A5,SUMF2,GAL3ST1,COX4I1,HS3ST5,CP,HAPLN1,CRY2,CS,CSNK1G3,VCAN,NCAN,SDC3,PLCXD3,CTH,PYGO1,BOC,HDAC4,SPOCK2,DBI,DBT,B3GAT3,SNAP91,SPOCK3,DLG3,DLG4,HS3ST4,HS3ST2,DYNC1I1,CDON,SLC25A18,ATN1,DYRK1A,EDN1,EFNB3,EGFR,EIF5,IRAK4,ELN,ENO2,EPHA5,GPHN,ERBB2,ERBB4,EXTL1,EXTL2,F3,PTK2B,FCGRT,FGF1,FGF12,FGFR1,FGFR3,CAP2,TPK1,B3GAT1,DOT1L,OGA,GAP43,SIGLEC8,MTHFD2,DNER,NEU3,GCK,ALDH1L1,SULT1C4,GFER,GHR,DHRS4,HPGDS,GLS,CBX1,PCSK1N,CNDP1,GPD1,GPD2,NUDT21,RAPGEF4,GRIA1,GRIA2,GRIA4,PLCD4,GRIK1,GRIN2C,GRIN2D,GRM1,GSTT2,GYG1,HAS2,HBA1,HPSE2,SYNPO,HMGCR,AGFG1,HSD17B1,HSP90AA1,IDH3A,IFI16,IGF1,IL6ST,INPP1,ITPKA,JAK2,KCNK3,KHK,LAMA2,MAG,MAT2A,CHST6,MSR1,MSRA,DDX25,RSPO2,HS6ST3,MYO5A,NBL1,NCAM1,NCAM2,OGG1,OLR1,PAH,PDE4B,ENPP2,PDPK1,GNG2,OLA1,PGAM2,SEMA5B,PIK3C2A,PLCB2,PLCD1,PLEC,PTPA,PPP5C,PRKCB,PRKCG,PKN2,PRKCZ,MAPK10,SLC26A11,PSMA6,LAMA1,PTK2,PTN,PTPRG,PTPRZ1,PTX3,DUSP15,RGS3,RNASE1,ROBO2,UEVLD,FBXW7,PTGR2,HSD11B1L,SELL,FOXRED1,SHMT2,FNDC3A,TMEM132D,SLCO1A2,RIMS1,SPP1,SPTB,PBLD,CLSTN2,THSD1,SULF2,ABCC8,ARHGEF9,PLCB1,NEU4,TF,CHST8,TGFBR3,HHIP,THBS4,THRA,TIAM1,TK2,TPD52L2,NPL,CHST5,TST,TTPA,CADM1,WRN,SLC13A3,WNK1,EMSY,GAL3ST3,MSRB3,NETO1,SENP7" Drug CID000003345 fentanyl Stitch 3.26E-03 1.00E+00 1.88E-02 2.14E-01 29 111 "ADRA1D,ADRA1B,AK2,APOC2,CACNA2D1,CALM1,TRAPPC9,DRD1,AASS,GRIN2C,GRIN2D,IL1RAPL1,TNFAIP8L3,KCNJ3,BCO1,NPY,NPPA,OPRL1,PDE3A,PDE3B,PDYN,PENK,ABCB1,PIK3C2A,PYGM,FEZF2,RYR1,RYR3,ARX" Drug CID000005262 AC1L1JYL Stitch 3.27E-03 1.00E+00 1.89E-02 2.15E-01 90 435 "ACTN1,ADCY5,PLA2G6,MRTFA,ANK1,ALS2,ARHGDIA,CERS5,ARHGEF1,CDC42,TIGD7,SOCS6,MYL6B,CLTB,ABCG1,PPP1R16B,PLCXD3,CTNND2,GIT2,BLOC1S6,SACS,DOCK2,EGFR,ERBB2,PTK2B,ACTL6B,FHL1,FOXO3,FLT1,B3GAT1,FYN,GART,DNER,GPR162,GPR12,LPAR4,PLCD4,GPR45,IGF1,SCIN,ITGAM,KCNN2,MATK,SHC3,MITF,GIT1,MYL3,NASP,NOS1,NPR2,PDGFRA,ENPP2,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PTK2,RGS3,RTKN,MAPK12,SMPD3,SELL,FNDC3A,ST8SIA1,SLA,PALLD,MYCBP2,NCDN,PLCB1,TACR1,TIAM1,ACTR6,CDK20,TRPC1,TSC2,UGT8,SPHK2,PLPPR5,PLD4" Drug 3188_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.27E-03 1.00E+00 1.89E-02 2.15E-01 45 192 "ABHD6,MTUS1,APBB2,ASPH,ATP6V0A1,TAOK2,ARHGEF6,PDE4DIP,CTH,DAPK3,HP1BP3,DSCAM,DTNA,FCF1,MBNL2,IRAK4,KAT8,FYN,ZNF44,MSL3,HTATSF1,MAP4K5,MAP4,NF1,SLC11A2,CAMKV,ZCWPW1,RGS3,EMID1,FNDC3A,PPP4R3A,WDTC1,ZHX3,THSD1,NXT2,VAMP1,TRIM2,AHCYL2,TK2,TMOD1,TMPO,RBFOX2,LMF1,ZBTB14,EMSY" Drug 4267_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.27E-03 1.00E+00 1.89E-02 2.15E-01 45 192 "MTUS1,APBB2,APOC1,ADAM15,KRIT1,SRSF11,PDE4DIP,SIDT2,STX2,RRAGB,FCGRT,FYN,B4GALNT1,KCNMB4,GPM6B,RASSF8,AGFG1,IL6ST,DIPK1A,INPP5B,NFIX,CNOT4,NUMA1,PIK3R1,STRN3,PRKAB2,RAD51D,RBBP6,REV3L,FBXW7,FBXO11,ZNF667,LIMCH1,BEX1,CEP68,ARHGEF9,DICER1,PARD3,WIPF1,XRCC4,SF1,EVI5,KCNAB1,MPPE1,UBE3B" Drug 6213_UP Syrosingopine [84-36-6]; Up 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.27E-03 1.00E+00 1.89E-02 2.15E-01 45 192 "AP2A2,PPFIA1,CDK5R1,ST3GAL5,ARHGEF2,LRRFIP1,MAGI1,RAB26,BAG4,CREM,KIAA0586,MFAP3L,DTNA,OPTN,MBNL2,ING4,LRRC23,STX2,TBC1D16,AMOTL2,C1orf61,GAB1,TRAF3IP2,ALDH1L1,SRCAP,TDRKH,GRB10,KCND3,KCNH2,KIF5C,NUMA1,SLC25A23,POLG,PRPH,CEP97,SEC61A2,RNASEL,ZNF821,ASAP3,SYBU,KDM3A,SPTAN1,TTBK2,ROBO3,NUP214" Drug 7106_DN GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.27E-03 1.00E+00 1.89E-02 2.15E-01 45 192 "APBA2,APP,SHROOM2,KRIT1,CLGN,ZFYVE9,ABCG1,FAM169A,MATR3,RUSC2,FAM13A,APH1A,MBNL2,PLEKHA1,EN2,EPB41L2,ETV1,DPYSL4,DENND2A,STON1,GPR37,PDE4A,PTX3,RAB3A,RAB5B,BSDC1,SH3BGR,PEX26,SMARCC2,SPTAN1,DIP2A,PHLDB1,EXOC7,TCF4,ARHGEF12,TMEM121,TRPC1,HIRA,SF1,ZNF45,EMSY,HPS4,MVB12B,PDSS2,SMIM8" Drug 4175_UP "Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.27E-03 1.00E+00 1.89E-02 2.15E-01 45 192 "ASIC1,BIN1,APC,CCDC181,N4BP2L1,BAIAP3,CAST,ADGRG1,MICAL2,CNTNAP2,DCT,EDNRA,LRRC23,EPHB1,SCARA3,C1orf61,OGA,FYB1,RUNDC3A,GNAO1,KIF5C,KPNA5,LAMA2,MDFI,MID1,ADAM22,GPR85,RETREG1,PURG,POU3F2,ACSM5,RASGRF1,MRAS,RASA3,ST6GAL1,PKNOX2,OGDHL,KIF21B,SOX10,BEX1,ATP10B,OBSL1,CRB1,TNS1,KAT6A" Drug 6902_UP 0297417-0002B [362658-29-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.33E-03 1.00E+00 1.92E-02 2.19E-01 44 187 "ASIC2,SLC12A5,ADORA2A,APLP1,SHTN1,ALDH4A1,ATM,ATP2B1,ZFYVE9,WHRN,DSCAM,DTNA,OPTN,MTSS1L,F3,BAIAP2,TRMO,SEPT9,ZNF276,STON1,GPER1,GRK4,IL6ST,MAN2A2,MAP4,ZNF862,SMIM7,PPM1B,FAM120C,CCDC25,SH3BGR,ZKSCAN3,ZHX3,IQSEC2,THSD1,AJAP1,ASTN2,ROBO3,MCF2L,EXOC7,TF,PARD3,TPM1,NAV2" Drug 4448_UP trifluoperazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.33E-03 1.00E+00 1.92E-02 2.19E-01 44 187 "ACTN2,ADD2,ADGRF5,ASTN1,SLC2A11,BMP7,CACNA2D1,CBS,TPP1,AKAP5,SLC4A7,AKAP12,CTH,SPOCK3,TRAPPC9,CDON,FGF13,ATP8A2,ADAM28,RND1,RAB30,STON1,CACFD1,GRM7,IL6ST,KCNA2,KCNH2,MOBP,NPY,PDGFRA,MARCH1,RET,RGR,RGS4,RGS12,TCP11L1,HKDC1,PKNOX2,ZBTB43,NPAS3,ARC,TPM1,CHST5,ZNF225" Drug 4589_UP Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.33E-03 1.00E+00 1.92E-02 2.19E-01 44 187 "ADRB2,PLA2G6,LTBP4,ALK,SLC4A4,BAIAP3,CAMK2B,CAPN3,CHRNB2,RAB28,QKI,CREM,PDE4DIP,BRINP1,EDN1,NRN1,AMOTL2,PDLIM5,GAP43,ALDH1L1,GPM6B,KCND3,KCNF1,SMAD1,MAPT,AFDN,OLR1,OXTR,PALM,PDE4D,PFKFB4,PTPRH,PTX3,RGS12,FBXW7,SEC14L1,RAP1GAP2,TEX15,TRIO,RUNDC3B,WNT7A,PMEPA1,SCG2,NAV3" Drug 1565_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.33E-03 1.00E+00 1.92E-02 2.19E-01 44 187 "NDRG3,ADD1,BEGAIN,MAP4K3,APBA2,MARK4,SYNJ1,CLCN3,PREPL,SORBS3,ING4,FAM49B,OGA,BRD8,GLUL,PCLO,DIDO1,IFI16,VWA5A,MKLN1,NUCB1,PIK3C2A,LRP12,PPP2R5C,CNNM2,SAMD9,PTAFR,RAB3IL1,TRIM68,RNASEL,HSPA4L,SLA,MAPKBP1,ZSWIM8,WASHC4,CRTC1,KAT6B,TPM1,ZKSCAN5,CLDND1,XPO1,ZNF32,LMAN2L,VPS35L" Drug 1794_UP Sulfaphenazole [526-08-9]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.33E-03 1.00E+00 1.92E-02 2.19E-01 44 187 "C1QTNF1,APP,BTRC,KIAA1549L,HOMER3,AKAP7,IQCK,BAG4,CHD1L,KLHL3,LYPD1,EDNRA,IRAK4,ELAVL2,CNTRL,HMGB1,HNMT,MDFI,ZNF862,NASP,CNOT4,OCRL,PIK3R1,RC3H2,MAPK3,CNNM2,GON4L,GTDC1,TTLL7,TRA2B,FERMT1,WDR37,SLC20A2,PEG10,SS18,STAU1,TCF7L2,ARHGEF12,CRTC1,TMPO,NSD2,SPHK2,SSPN,AAAS" Drug ctd:C084597 chlorcyclizine CTD 3.34E-03 1.00E+00 1.93E-02 2.19E-01 24 87 "SERPINA3,SRPX,CAMK2G,HAPLN1,ABCG1,ELN,SEMA6C,GABRB3,CPLX1,WIF1,IL6ST,LSS,MAPT,MBP,MYBPC1,NCAM1,TMOD2,ABCB1,PIK3R1,KHDRBS2,SMPD3,SMARCA4,CDH22,TST" Drug CID000000316 CMP-Neu5Ac Stitch 3.34E-03 1.00E+00 1.93E-02 2.19E-01 35 141 "SLC12A5,NRP2,ST3GAL5,B4GALT6,SLC22A6,CNR1,DCT,SLC12A6,GNE,ST8SIA3,EDN3,EDNRB,VPS13B,ST3GAL6,ST6GALNAC3,B3GAT1,NEU3,MAG,KITLG,NACA,NCAM1,ST8SIA5,SCNN1D,ST6GAL1,ST3GAL3,ST8SIA1,SLC8A1,SLC12A2,SLC12A4,ADGRL3,NEU4,NPL,WNK1,WNK3,ST8SIA2" Drug CID000002162 amlodipine Stitch 3.35E-03 1.00E+00 1.93E-02 2.20E-01 32 126 "ADD1,ADRA1B,AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNG1,CALM1,NGB,CAMK2B,CHRM1,NOS1AP,MYEF2,EDN1,SMC2,GCNT2,ATF7,HBA1,KCNA4,NOS1,CNTN3,ABCB1,PKD1,KLK6,TAC1,TAC3,NETO1" Drug CID005743034 "3,4-dioctylphthalic acid" Stitch 3.35E-03 1.00E+00 1.93E-02 2.20E-01 32 126 "ACADM,USP6,DLG4,DMPK,DRD1,DYRK1A,EGFR,ERBB4,CACNG2,POLK,INPP5K,ACSS1,GGT7,GGT5,PPARGC1A,GRIA1,GRIA2,GRIA4,CIT,HPSE2,CPT1C,IGF1,KCNJ16,KITLG,NOS1,ABCB1,PPARA,GSTCD,SOX10,DDN,TP53BP2,FTSJ1" Drug CID000034274 uldazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug ctd:D005045 Etomidate CTD 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "CACNA1I,GABRA1,GABRA5,GABRB1,GABRB3,GABRG2" Drug CID000189875 menitrazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000031157 triflubazam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000164934 Gt12 Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "APP,CDC42,WDR20,MEST,MAPK9,MAPK10" Drug CID000008718 "2,5-dimethylquinone" Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CHRDL1,ATP2C1" Drug CID000037114 fosazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000036834 fletazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000027452 C19H18ClN3O Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug DB01023 Felodipine Drug Bank 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "CACNA1D,CACNA2D1,CACNB2,CALM1,CACNA2D2,PDE1B" Drug CID000014491 "1,6-hexanedithiol" Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ABHD6,DMPK,DTNA,GCK,SNCA,ADHFE1" Drug CID000120282 phenazine-1-carboxamide Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "SEMA6A,PNKD,PTPN5,HP,HPR,PLEC" Drug ctd:C422415 farglitazar CTD 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ATP1A1,PPARGC1A,NR3C1,MED1,RXRA,SGK1" Drug CID000012685 DEMP Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ACHE,BCHE,DMTF1,NBL1,PIK3C2A,SARS" Drug CID000486048 Sm28 Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "SUMF2,NELFCD,MAP4,PPP2R2C,GSTCD,ABCC8" Drug CID000123310 PbCl4 Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "APLP1,GRM1,GRM3,GRM5,NCAM1,ST8SIA2" Drug CID015942721 Bu-1014 Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000069892 0-ol Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "DMPK,GRIA1,GRIA2,GRIA4,GRM3,NBL1" Drug CID000155723 N-anisoyl-GABA Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "BCHE,GRM1,GRM2,GRM5,GRM8,HTR2A" Drug CID000006616 camphene Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "TOX,SPEG,EYA1,KCNH1,PCSK5,MASP1" Drug CID000065445 elfazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000003400 flutoprazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000068832 Zapizolam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000004345 arachidonoylglycine Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "CACNA1I,CACNA2D1,CBS,CNR1,E2F6,ADHFE1" Drug ctd:C067113 SK&F 81297 CTD 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "DRD1,PPP1R1B,ARPP21,GRIA1,PDE1B,MAPK3" Drug CID000115067 gastrodin Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ABAT,CACNA1B,CACNA1E,SCN2A,SLC6A1,SLC6A11" Drug CID006327614 borazine Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ARSE,CP,POLL,PMP2,SPP1,TMEM121" Drug CID000037367 camazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID003081964 ADP-beta-F Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ADORA1,ADORA2A,ADORA3,CD38,GK,PKM" Drug CID000424361 4-aminopiperidine Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "CACNA1A,CACNA1B,DRD1,B3GAT1,PENK,TACR1" Drug CID003052777 Reclazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000017931 sulazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000011955 benzohydrazide Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ABAT,CD38,POLL,TMEM132D,CLSTN2,TSC1" Drug CID000041637 Serin hydrazid Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000068777 iclazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID011171679 D1-G Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "DLG4,SLCO1C1,SLC15A2,SLCO1A2,SLC22A4,TJP1" Drug CID005284402 indolidan Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ALDH7A1,CALM1,PTPN5,HP,HPR,PDE2A" Drug CID000065803 Arfendazam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000148200 YM872 Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "ABCG2,GRIA1,GRIA2,GRIA4,GRIK1,GRM3" Drug CID000121919 gidazepam Stitch 3.39E-03 1.00E+00 1.95E-02 2.22E-01 6 11 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug ctd:C017096 n-butoxyethanol CTD 3.40E-03 1.00E+00 1.95E-02 2.22E-01 117 587 "ADCY6,ADD2,BIN1,ANK1,GAS7,LGR5,PDXK,ARRB1,BACH1,SEC11C,NRP2,BLM,PROM1,OSGIN2,HAP1,CDC25B,CDH2,UBE2L6,FADS2,PCYT1B,CP,RBM39,AKAP12,CSNK1E,APPL1,UBXN2A,CX3CR1,CYBB,CENPL,PHYHIP,ZEB2,RHOBTB1,RABGAP1L,DPYSL2,EBF1,EDN1,EDNRB,FEM1B,RASGRP1,EEF1D,OPTN,ABI2,EIF5,EPB41,DMTN,EPS8,DENND4A,SH3YL1,ACSL4,PTK2B,ST3GAL6,FOXO3,FLT1,SORBS1,TMEM107,SMC2,TRAF3IP2,BRPF3,MTHFD2,CPLX2,PPARGC1A,TUBA1C,GSTM5,MAP4K5,WIF1,BACH2,SYNPO,IFI16,IGFBP1,LIG4,MEF2C,P2RY13,DDR2,PC,PDE4B,PDGFRA,PFKFB3,ANLN,PIK3CD,PIK3R1,GPSM2,SMOX,PKN2,MAPK8,GDPD1,RELN,CNNM2,PTPRD,RGS3,RGS12,HES6,SOX6,GALNT10,HSPA4L,SGK1,ITSN1,SHMT2,ST6GAL1,SMTN,SLC6A9,CPEB4,SNCA,PALLD,SP4,SPTB,SEMA4A,PJA1,TCF4,SIRT1,TMOD1,TNFRSF1B,UBC,UBE2H,VAV2,WRN,PMEPA1,LRP8" Drug 1661_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.40E-03 1.00E+00 1.95E-02 2.22E-01 43 182 "SLC12A5,C1QTNF3,CDC42BPA,MARK4,CFLAR,FOXN3,ENTPD4,SH2B1,CSNK1E,PDE4DIP,CTH,HP1BP3,TOM1,CELSR3,ING4,INPP5K,BRD8,ZNF276,RAB40B,STON1,ICA1,ADAM22,NEK1,PDPK1,MINDY2,PTCH1,ARID4A,RGS3,RGS10,CARF,PCMTD2,NEK11,TCP11L1,WLS,KDM3A,IQSEC2,CEP68,PLCB1,TRIM2,PCDHA6,BEX4,UBE2H,SPHK2" Drug CID000005253 sotalol Stitch 3.40E-03 1.00E+00 1.95E-02 2.22E-01 21 73 "ADRA1D,ADRA1B,ADRB2,CFLAR,CACNA2D1,ASIC3,PNKD,IP6K2,MAP4K5,KCNA1,KCNA2,KCNA6,KCNB1,KCNH2,KCNQ2,KCNQ3,ENPP2,SCN4B,SCN3B,HPS4,KCNAB1" Drug CID000002761 CAS 298-57-7 Stitch 3.40E-03 1.00E+00 1.95E-02 2.22E-01 21 73 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CACNA2D2,DRD1,CACNG7,CACNG3,CACNG2,PKD1,RYR1,RYR3,SOX10,TPCN2" Drug CID000333446 arginyl-lysine Stitch 3.42E-03 1.00E+00 1.96E-02 2.23E-01 15 46 "APLP1,APP,DTNB,USH1C,F3,F5,FCGRT,OPRL1,PDYN,PENK,RIT2,SCG5,SST,ABCC8,TMPO" Drug CID006102719 2gzl Stitch 3.42E-03 1.00E+00 1.96E-02 2.23E-01 15 46 "AMPH,CDR1,VCAN,CHRDL1,DNM1,DNM2,DNM1L,HIPK3,GMPR2,MX1,NPPA,PTPRN,GSTCD,DDN,WIPF2" Drug ctd:C030691 gluconic acid CTD 3.42E-03 1.00E+00 1.96E-02 2.23E-01 15 46 "SLC22A6,CLCN3,VAX2,SLC32A1,CSF1R,SIRPA,ARNT2,NR1D2,SLC12A6,SEMA6C,FYN,KCNC1,RXRG,SLC6A8,SLC15A2" Drug CID000005839 aldosterone Stitch 3.44E-03 1.00E+00 1.97E-02 2.24E-01 83 397 "NDRG2,ADAR,ADD1,ADD2,MTUS1,AGT,NR0B1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,USP2,CBFA2T2,LONRF2,CACNA2D2,ASIC3,COL11A2,NCOR1,NCOR2,CS,DBI,DCT,EDN1,EDN3,EDNRA,EDNRB,CACNG7,EGFR,CALCRL,CACNG2,PTK2B,TUBB3,NR3C1,HSP90AA1,KCNMA1,MMP16,MMP17,MYH6,NPY,NPPA,NPR2,OLR1,ABCB1,PKD1,PPARA,PPP3CA,PPP3CC,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK7,KLK6,RXRG,RYR1,RYR3,SCN4B,SCNN1D,SGK1,FNDC3A,SLC12A2,SLC14A1,SCN3B,SPP1,TAC1,TAC3,CABIN1,RBFOX2,TTPA,SGK3,WNK1,CBLN2" Drug 4495_UP (-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.46E-03 1.00E+00 1.98E-02 2.26E-01 42 177 "PRX,CCDC181,SLC4A4,C5,IL33,MAP7,STOML1,WHRN,CREM,AKAP12,PHF14,CTH,ARHGEF4,PITPNC1,NCALD,ETV1,ARMCX1,DLC1,ATP8A1,TACC2,GPD1,GRIK5,CACFD1,PADI2,IRF8,JAK2,NPY,PDE3B,PDE4B,PDE4D,PIK3CD,SMOX,PMP22,PTHLH,ZSCAN32,AP1AR,ZHX3,TBL1X,PSD3,CRTC1,TNS1,ZBTB38" Drug CID000000784 H2O2 Stitch 3.49E-03 1.00E+00 2.00E-02 2.27E-01 220 1183 "ACHE,ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,AMPH,APC,APLP1,MAGEE2,DDO,APP,CDK10,PRX,PDXK,ARHGDIA,DYNLL1,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ALDH7A1,BARD1,BCS1L,CFLAR,BTK,CACNA1A,CALM1,NGB,CBS,CCK,CCNT1,AIFM1,SCARB1,LRBA,CDH2,CDO1,CACNA2D2,CLCN3,CLCN4,COL9A1,COL9A2,COL9A3,CP,CREM,HAPLN1,GDA,CS,PLCXD3,CYBB,CHRDL1,DOCK2,ACOT8,ABI1,RCAN1,DTNB,TOM1,DNM1L,ABCC9,AASDH,EDN1,EGFR,COQ7,ERBB2,ERBB4,PIPOX,F3,TUBA1B,PTK2B,FCGR3A,FDFT1,FECH,ACTL6B,FGFR1,POLK,SCARA3,PCYOX1,FOXM1,FOXO3,SMC2,ATP6V1H,DNER,SESN1,GFER,GK,AIFM3,KCNMB4,LOXL3,GNAS,GPD2,PLCD4,GRIN2C,PTPN5,HBA1,TNFAIP8L3,HMGB1,HMGCR,HP,HPR,HSP90AA1,IGF1,IL12A,ITGA7,ITGAM,KCNA4,KCNB1,KCND2,KCND3,KCNJ4,KCNMA1,STMN1,LIG4,ASPRV1,MAOB,MBP,MIA2,PPM1L,SESN3,MSR1,MSRA,NCF2,NDP,NDUFA5,NFE2L2,NFIX,NOS1,SLC11A2,NTRK2,NUMA1,OGDH,OGG1,OLR1,PAH,KCNK10,PAX6,PDYN,PENK,ABCB1,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,SMOX,PMP2,FA2H,POLG,PPP2R2B,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRODH,NDUFS7,PTK2,PEX5,PPP2R3C,RBBP8,REV3L,GSTCD,RPE,RXRG,RYR1,RYR3,S100B,MAPK12,SMPD3,HSPA4L,FNDC3A,SLC1A2,SIRT2,SLC11A1,SLC12A4,ZNF667,SNCA,SST,ADHFE1,MLC1,ABCC8,PLCB1,SYP,SYT1,MMS19,FBXW11,SMG6,CYB561A3,SIRT1,SPX,TJP1,ACTR6,TMPO,TNNT1,CABIN1,PIK3R5,RBFOX2,SMUG1,NEIL2,TRPC1,TRPM2,TSC2,TST,UBC,WRN,TUBA1A,PLD4,MSRB3,NETO1" Drug CID000023954 silver nanoparticles Stitch 3.51E-03 1.00E+00 2.00E-02 2.28E-01 41 172 "APAF1,MPDZ,CACNA1A,AP4M1,CNR1,HDAC9,DYNC1I1,ATN1,DTNB,EN2,ENO2,F8,PPP1R1B,FOXG1,ARFGAP2,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSP90AA1,MAOB,MEIS1,NAP1L2,OGG1,PAH,PENK,PMP2,PACSIN1,PTK2,QDPR,FBXW7,SARS,ATXN7,FOXRED1,COPZ1,SLC1A3,SNCA,NPL,JPH3" Drug CID000004591 AC1L1IIA Stitch 3.51E-03 1.00E+00 2.00E-02 2.28E-01 41 172 "AK2,ATP1A1,ATP1A2,ATP1A3,ATP1B3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,NAE1,CFAP410,CALM1,SLC25A14,ENTPD2,CDR1,COL4A5,SLC25A27,CS,CYBB,AK5,DMPK,FKTN,AK8,ATP6V1H,ATP2C1,GATM,GCK,GK,GPD1,GPD2,LSS,NPTX2,OGDH,PFKFB3,ABCB1,DUSP15,S100B,ABCC8,TCEA1,CYB561A3" Drug CID006918236 perzinfotel Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C" Drug CID000015778 isopropyl methylphosphonic acid Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ACHE,BCHE,DMTF1,PC,PIK3C2A" Drug DB00651 Dyphylline Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ADORA1,ADORA2A,PDE4A,PDE4B,PDE4D" Drug CID000083651 I50 - 9 Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "EGFR,ERBB4,MAPK3,MAPK9,MAPK10" Drug CID000007549 NSC73599 Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ARHGAP32,DTNB,DNER,HNMT,RDX" Drug DB01054 Nitrendipine Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "CACNA1D,CACNA2D1,CACNB2,CACNG1,CACNA2D2" Drug DB01244 Bepridil Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ATP1A1,CACNA1A,CALM1,CACNA2D2,PDE1B" Drug ctd:C494355 desisobutyrylciclesonide CTD 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ABCG2,NR3C1,ABCB1,MAPK8,MAPK9" Drug CID000133881 D-box Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ACHE,BCHE,NR3C1,HSP90AA1,ZIC3" Drug CID000128784 "1,3-dipropyl-8-phenylxanthine" Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ADORA1,ADORA2A,ADORA3,DPP6,TUB" Drug CID000130349 NSP-805 Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ALDH7A1,CALM1,KRIT1,PDE2A,PDE3A" Drug CID006440491 neoxaline Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ACHE,CBS,IL6ST,PKM,PKIA" Drug ctd:C056723 FG 9041 CTD 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "CHRNA4,CHRNB2,GFAP,NEFM,PENK" Drug CID000009330 benactyzine Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ACHE,BCHE,CHRM1,GART,SPP1" Drug CID000056207 sarafloxacin Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "F3,ZMYND10,PDCD2,SLC14A1,TRIO" Drug DB00228 Enflurane Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ATP2C1,GABRA1,GRIA1,KCNA1,KCNMA1" Drug DB01115 Nifedipine Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "CACNA1D,CACNA2D1,CACNB2,CALM1,KCNA1" Drug DB00619 Imatinib Drug Bank 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "DDR1,CSF1R,KIT,PDGFRA,RET" Drug CID000131900 peimine Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "ZNF274,KIT,TAC1,TACR1,ZBTB14" Drug CID000128590 Amino-senktide Stitch 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "OLFM1,B3GAT1,TAC1,TAC3,TACR1" Drug ctd:D005442 Flumazenil CTD 3.53E-03 1.00E+00 2.00E-02 2.28E-01 5 8 "GABRA1,GABRA4,GABRB1,GABRB3,GABRG2" Drug CID000064961 beta-carboline Stitch 3.54E-03 1.00E+00 2.00E-02 2.28E-01 19 64 "ABAT,BCS1L,CCK,DBI,DMTN,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GLRB,LOXL3,MAOB,NLGN3,SYNE1" Drug CID000004902 AC1L1J7N Stitch 3.54E-03 1.00E+00 2.00E-02 2.28E-01 19 64 "ANK2,CBR1,DBI,STX2,TUBB4A,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIA2,GRIK1,GRIK2,GRIN2C,GRIN2D,FNDC3A,SLCO1A2,SLC17A6" Drug CID000005697 xanthine amine congener Stitch 3.54E-03 1.00E+00 2.00E-02 2.28E-01 19 64 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,NOG,CFL2,B4GALT6,CTH,DPP6,ABI2,GSN,KLHL23,ENPP2,BEX1" Drug 1800_DN Allantoin [97-59-6]; Down 200; 25.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADGRF5,BIN1,APOC1,APP,SEMA4G,MARK4,CFLAR,CA12,SLC4A7,SDC3,DAPK3,KIAA0753,PARD6A,TMCC2,FEM1B,SCML2,BAIAP2,INPP5K,SRCAP,DIDO1,DHX35,SHISAL1,MITF,MX1,ODF2,SSH1,SLC25A23,FA2H,MCMBP,ASAP3,ANKRD6,SLC1A3,LIMS2,ELOVL4,EXOC7,EHBP1,TCF7L2,TRIM2,NSD1,CABIN1,FAM155A,UBTF,LMF1,XRCC4,HPS4,MPPE1" Drug 7252_DN Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BIN1,PPFIA3,APP,MTMR9,KYAT1,IQCK,SMARCAL1,NCOR1,USP6NL,DCAF8,B3GAT3,PARD6A,TNK2,FCGRT,FHL1,ARFIP1,SESN1,TXNL4A,GNAS,NR3C1,SLC2A6,KHK,MEIS1,MYO6,NRGN,OCRL,ODF2,CCSER2,NLE1,MBOAT7,POLG,FSD1,SYTL2,SEC14L1,PEX26,ELMO2,CDK5RAP2,IFT122,ZNF415,SPATA7,CLUAP1,TGFBR3,LMF1,MPPE1,NUP214,TIGD6" Drug 1798_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "TRMT9B,CDC42BPA,ALDH4A1,BLM,LDLRAD4,CBFA2T2,ARHGEF2,LARGE1,PLAA,NRG2,VCAN,TRAPPC9,CDON,EDNRA,FEM1B,COQ7,TRMO,TPK1,DLL3,GAD1,SEPT9,GCNT2,ARFIP1,GPR17,GPR37,CNTRL,ITGA7,KPNA5,MATN3,CLDN11,PC,PDE1C,RAD51D,ATG16L1,FNDC3A,PEX26,SLC14A1,ZHX3,UNC5B,LHPP,NXT2,SYT11,ATP11A,TRIM2,THRA,CABIN1" Drug 6183_DN trifluoperazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,APOC1,APP,NFS1,SLC4A7,NCOR1,EDRF1,TM9SF4,DNM2,DTNA,PLXNC1,ERCC2,DLC1,CAMKK2,SRCAP,ADAM28,GLYR1,TJAP1,SMAD1,MAP4,NINJ2,PDE4A,KCTD15,C1orf109,FOXRED2,SLC1A3,SLC6A8,SLC11A1,BTBD7,SMARCA4,KIF21B,ZHX3,DDN,SRPK2,FCHO1,VAMP1,KAZN,TCF7L2,SZT2,PARD3,FLRT2,PLPPR2,VIPR2,XRCC4,ZNF225,NLRP3" Drug 3542_DN Prednicarbate [73771-04-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AMPD3,BIN1,APBB2,RGS20,PDE8B,RASL11B,SYNJ2,CFAP410,IQCK,WHRN,RIMS3,SMG7,EFNA3,CELSR3,VPS13B,VPS26C,ACSL4,FHL1,FAM49B,OGA,GAB1,GRIK5,GRM1,ATXN2L,INPP1,MIA2,ADAM22,NNAT,CNOT4,NTRK2,OPCML,RETREG1,PRKAR1B,PRODH,WLS,SEMA6D,FAM214B,WDTC1,TSPYL2,CLSTN2,PHLDB1,STX1A,POPDC3,ROBO3,TMOD1,PRDM2" Drug 4700_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NME5,SYT13,AMPD3,KCNAB2,PDE8B,BAIAP3,LDLRAD4,CALB1,CAMK2B,CACNA2D2,QKI,CTH,CYBB,RASSF2,C2CD2L,FHL1,AFF2,FUT9,GAD1,GALC,DISC1,TDRKH,KLF12,MAG,MEF2C,KITLG,NFYA,NTRK2,TREM2,CDK18,POU3F2,MAPK10,RPS6KA2,RASA3,SLC1A2,PREX2,CCDC88A,SLC20A2,DMXL2,PCDHA6,SEZ6L,NSD2,XRCC4,ZFP37,ZIC3,ZNF24" Drug 3679_DN Flurandrenolide [1524-88-5]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APC,APP,ATM,ADAM15,CFLAR,IL33,CBFA2T2,CDH2,IQCK,CHD1L,HAPLN1,PDE4DIP,ARHGAP32,CNIH3,DMPK,CDON,FAM13A,SUGP2,GBX2,GPR19,CNTRL,KCNMA1,KHK,MIA2,TAGLN3,PPP5C,CNNM2,PTHLH,ZNF821,SH3GL2,PPP4R3A,SLC20A2,KIF13A,EMC1,ARHGAP26,CDK19,SS18,NXT2,MAPK8IP3,PHLDB1,SYT11,KIAA1107,RUNDC3B,ZMYND8,RPRM,NSD2" Drug 2293_UP Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,NME5,ADGRF5,AMPH,GAS7,DNAH17,ATP2B2,ST3GAL5,BTRC,CACNG1,CCKBR,ARHGAP33,CLGN,CHN2,FADS2,ARHGEF10,NCAN,SHANK1,EDNRA,EFNB3,EN2,LYVE1,GPM6A,NR3C1,PTGDR2,KCND3,TAGLN3,NTRK2,PDE4B,PDE4D,PFKFB2,KCTD17,BCAN,TNIK,NMNAT2,SPTB,ATP10B,POPDC3,WSCD1,SLC35G2,TEX15,TPM3,UGT8,FLRT2,SF1,SLC17A6" Drug 7431_UP Dimenhydrinate [523-87-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "PPFIA3,ATP2B1,MPDZ,CA12,INA,FADS2,HOMER3,FEZ1,ARHGEF4,GIT2,ATN1,MAMLD1,PHF20L1,MBNL2,COQ7,F8,ZNF589,FGF12,FHL1,ANKFY1,GPR153,GALC,TMEM8B,MALT1,GPM6B,NR3C1,RNFT2,ADAM22,NACA,NOVA2,SLC11A2,SETD4,MINDY2,PTPRE,PEX5,RIPOR1,RNASEL,SCMH1,NCDN,MAPK8IP3,VAMP1,ARHGEF9,ASTN2,PSD3,TPD52,MVB12B" Drug 6161_DN Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,RAB33A,ZFYVE9,SEC31B,CRY2,EDRF1,RIMS3,CDKL3,FGFR1,FAM49B,GRIK5,GRM1,ICA1,ITIH2,MIA2,MOBP,OLR1,CCSER2,PLCD1,PEX5,RIPOR1,BSDC1,RET,GSTCD,ZNF821,AMBRA1,SLC1A7,RBM26,SS18,STX1A,JMJD6,PLCB1,DNMBP,KIAA1107,TCF7,TNS2,AP4E1,TGFBR3,SLC44A1,TNNT1,ZKSCAN5,VIPR2,ZIC3,ZNF32,KCNAB1,KAT6A" Drug 3843_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "MRTFA,DOC2A,AMH,APBB2,MARK4,ARHGAP33,TAOK2,SIPA1L1,SDC3,RIMS2,EXOG,DNM1,TNK2,DMTN,FGFR1,FOXG1,GFER,USP19,GLS,NR3C1,HNMT,INPP1,ADAM22,NPR2,NRGN,NTRK2,PLCD1,PLEC,SNRK,TMEM104,WDR25,ZSCAN2,RAD52,ZMAT4,EMID1,BTBD7,SMARCD3,IQSEC2,TTBK2,TCF7,RUNDC3B,VIPR2,KCNK12,XRCC4,EVI5,SSPN" Drug 3670_UP Kawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA3,APP,CDC14B,CADM3,ATP6V0A1,ADAM23,HIP1R,MAGI1,CDO1,CHI3L2,SLC24A2,COL9A2,CSF1R,RIMS2,CTIF,MFAP3L,ECM2,EGFR,TNK2,MTSS1L,CAMSAP1,SEMA4D,GAB1,GALC,SYT17,ALDH1L1,ITGA7,MDM4,MOBP,MYT1,NCAM2,GPR85,SMOX,PLP1,MINDY2,LRRN3,RASA3,ARHGEF40,SLC15A2,KDM4B,NFASC,PLCB1,ADGRL3,TRIO,TRO,SENP7" Drug 1491_DN Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABR,NDRG3,PPFIA3,ARRB1,CAPRIN2,ATP6V0A1,BCL7A,PDE4DIP,KIAA0586,HP1BP3,RCAN1,OPTN,CDKL3,SYT17,TXNL4A,GNG4,TDRKH,NR3C1,ICA1,MIA2,NF1,NFYA,PRKAR1B,MAPK7,PRPH,TMEM104,RIPOR1,RAB3IL1,RAD51D,SEC61A2,RNASEL,ITSN1,ABLIM3,KDM4B,PHLDB1,ATP11A,MCF2L,EXOC7,TBL1X,KCTD2,PARD3,ZMYND8,VAV2,NDRG4,GDPD5,AAAS" Drug 5412_DN Clebopride maleate [84370-95-6]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "RALGAPA1,EPB41L5,FAM131A,BCAS1,CASK,SLC4A4,SYNJ2,TPP1,QKI,RCHY1,BAG4,SH2B1,CRY2,PPP6R2,EDRF1,TBC1D5,KIAA0586,DBT,TRAPPC9,DTNA,CNNM1,CELSR3,ING4,ANKMY1,EZH1,EFCAB2,SPACA9,HNMT,KCNH2,IPO5,NF1,FAM120C,PEX5,ZDHHC14,TCP11L1,PAQR6,ASAP3,WDTC1,VAMP1,PLCB1,SEMA4A,SLC44A1,VGF,EVI5,ST7,KAT6A" Drug 4004_DN Boldine [476-70-0]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,GAS7,APP,SLC4A4,ST3GAL5,CBFA2T2,TAOK2,DNAJB5,CNTNAP2,MFAP3L,PLPPR4,PARD6A,DLG3,DTNA,EFNA3,FAM13A,MBNL2,PLEKHO1,MFSD10,COQ7,DLC1,ANKFY1,TRMO,ZNF276,NR3C1,IL11RA,NDP,PAK3,NLE1,PRPH,RALGDS,FBXW7,IL17RB,SLC6A9,SMARCD3,IFT122,TMCC1,ARHGEF12,TK2,CABIN1,SMUG1,SSBP2,LMF1,REEP1,NT5M,UBE3B" Drug 3575_DN Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AMPD3,APBB2,PLA2G4C,CACNB2,CAMK2G,CRLF1,NMT2,FAM189A2,CREM,HDAC4,ZNF804A,KBTBD11,DTNA,TOM1,SUGP2,ACSL4,CAMSAP1,HBS1L,GPR37,HNMT,IL6R,OGG1,PDE3B,SERPINE2,ELOVL2,PEX5,RAB3A,SMTN,FAM214B,MAPKBP1,ZCCHC24,ZHX3,EMC1,KDM4C,AJAP1,SEMA4A,EXOC7,KIAA1107,IQCE,ATP13A2,DICER1,THRA,CDK20,MICAL1,XRCC4,AAAS" Drug 1592_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ACTN2,NDRG2,PLA2G6,CNTNAP1,SHROOM2,BMP7,MTMR3,BAIAP3,RAB28,PCYT1B,CRYM,CTIF,ZNF804A,EFNB3,CELSR3,EGR3,EPHB1,CEND1,CD320,F3,OLFM1,CAMSAP1,C1orf61,EVL,OGA,GART,MPP2,NOS1,NTRK2,NTRK3,OMG,PIK3R1,PLCD1,PMS2,PACSIN1,POLG,GAL3ST4,MYH14,SUPT20H,SLC1A7,PEX26,FNBP1,THSD1,THRA,FLRT2,XRCC4" Drug 5352_UP Caffeic acid [3331-39-5]; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABHD6,AP2A2,FAM131A,APOC1,ATP6V0A1,CA4,CAMK2G,SLC16A4,ZFYVE9,CPS1,SH2B1,CRY2,PPP6R2,DAPK3,SGSM2,DTNA,SMC2,SRCAP,FERMT2,TDRKH,GPER1,KCNMA1,LSS,MGAT3,LYRM9,SLC11A2,PIK3R1,RETREG1,TNPO2,GON4L,FAM120C,RGS3,RGS10,GSTCD,SH3BP2,FNDC3A,ZCCHC24,PSD3,AP4E1,TRPC1,TRPM2,VAV2,EVI5,KCNAB1,MPPE1,UBE3B" Drug 6202_DN wortmannin from Penicillium funiculosum; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AGT,MRTFA,AMT,ANK2,APAF1,CASK,NUMB,KIF1A,SLC25A14,CAPN3,CARS,TAOK2,CREM,CTH,EDRF1,TBC1D5,RUSC2,PCOLCE2,TUBD1,COQ7,FYN,GAB1,SEPT9,INPP5K,GART,GNG3,TJAP1,IL6ST,SLC11A2,TRHDE,MAPK8,TMEM104,C1orf109,RAD52,SLC20A2,DDN,EXOC7,KCTD2,TPM1,TSC2,PLPPR2,VIPR2,VLDLR,LAT2,XRCC4,KCNAB1" Drug 6279_UP Ifosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APP,ARRB1,PDE8B,NEURL1,PLEKHB1,QKI,CNTN1,FAM149A,SIPA1L1,KBTBD11,DSCAM,EDNRA,F5,FER,KIAA1109,FGFR3,FHL1,KHDRBS3,GABRA2,DISC1,GPR19,CNTRL,TJAP1,MAP4,TAGLN3,ZNF862,NDUFA5,NF1,OGG1,POLG,MYH14,ROM1,EMID1,FNDC3A,PPP4R3A,SHANK2,SORCS3,SNCA,TMCC1,SPTAN1,CLSTN2,INKA2,TTBK2,ACSBG1,CABIN1,PLPPR2" Drug 6292_UP Metolazone [17560-51-9]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "KLRC4,KIDINS220,C1QTNF3,CDC14B,KIF1A,BCL2L2,CAMK2B,CBFA2T2,NEURL1,CHN2,FADS2,COL9A3,NCOR1,BRINP1,MFAP3L,RUSC2,DTNA,EFNA3,CELSR3,MBNL2,PLXNC1,ELAVL3,STX2,GRM1,SCIN,ITGA7,NELL2,NF1,PDE4B,LRRN3,SAMD9,PTCH1,TMEM231,RFX2,SLC20A2,ZNF415,MLC1,ARHGEF9,EXOC7,FBXW11,CHST8,CABIN1,TRIO,NDRG4,KCNAB1,MVB12B" Drug 2626_DN N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "C1QTNF3,APBB2,ARHGDIG,ALDH4A1,KIF1A,SYNJ2,CCNT1,PLEKHB1,SLC4A8,FEZ1,SIPA1L1,DAPK3,SMG7,DNM1,EFNB3,EGFR,IRAK4,ING4,CDKL3,F3,FHL1,ERAP1,GNG4,GPER1,BTN2A1,MAP4K5,HNMT,LIG4,MAP4,SLC11A2,PDE3B,RETREG1,RAB3IL1,RAD52,ZCWPW1,ZDHHC14,SH3BP2,SMTN,SNCA,CAMTA2,CEP68,ANKRD12,PARD3,CABIN1,XRCC4,ZBTB14" Drug 347_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ARID1A,NDRG2,ADD2,GAS7,CDK10,ARSF,MARCH3,BCL7A,BTRC,CHRNA4,CHRNB2,EPS15L1,HOMER3,IFFO1,AATK,PPP6R2,RIMS3,KLHL3,SORBS3,ELAVL4,ZMYND10,TRMO,KHDRBS3,ADAM28,HPGDS,GRB10,ATXN2L,FXYD6,NOS1,SETD4,PLCD1,MAPK8,FOXRED2,ZNF821,ITSN1,FERMT1,ANKRD12,CRTC1,GPR161,KAT6B,WIPF1,NSD2,SPHK2,ZNF142,ZNF154,PCBP4" Drug 2847_DN Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABHD6,AMPD3,FAM131A,APOC1,SYNJ2,GYG2,CAMK2G,SCARB1,RCHY1,BAG4,CREM,PDE4DIP,FAM169A,LYPD1,TOM1,CELSR3,IRAK4,ING4,DMTN,FAM198B,ACSL4,SRCAP,POLL,GIT1,NRGN,SETD4,ZSCAN2,ZDHHC14,RGS3,RGS10,ANKRD6,SLC6A8,BTBD7,ZCCHC24,UHRF1BP1L,SPTAN1,SUPT5H,ARC,EXOC7,ARHGEF12,SLC44A1,PARD3,CABIN1,LMF1,REEP1,SEMA3B" Drug 7083_UP pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "RBM10,BRAP,AK2,ALCAM,PPFIA3,BMP7,GYG2,BAIAP3,CFAP410,MAGI1,TENM4,PDE4DIP,DOCK4,OPTN,EFNB3,FGFR1,AGAP2,EFCAB2,INPP5K,GPER1,KCNJ3,LYRM9,PDPK1,RETREG1,KCTD15,PPP2R5C,PRKAR1B,FAM184A,GTDC1,RGS10,FBXW7,RPS6KA2,SUPT20H,FAM214B,SHANK2,WDTC1,ARHGAP26,SPTAN1,CLSTN2,THSD1,DIP2A,EXOC7,CABIN1,HIRA,PRDM2,ITM2C" Drug 1831_DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABR,ABHD6,ADGRF5,APOC1,CDK10,ADAM15,CFLAR,CA12,SCARB1,AP4M1,HOMER3,DZIP3,SGSM2,FEM1B,EFNA3,ERCC2,FHL1,GAD1,DISC1,INPP5K,GART,USP19,GPER1,AGFG1,SMAD1,MX1,NFYA,ODF2,PLEC,GRAMD1C,TMEM260,KIRREL1,SIRT2,BTBD7,ZNF415,EMC1,SS18,ARHGEF9,EXOC7,RBFOX2,VAV2,LMF1,NSD2,PRDM2,NT5M,SMIM8" Drug 7353_UP Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,BIN1,APBA2,ARHGDIG,STX16,SYNJ2,CALB2,CAMK2G,SCARB1,CLCN4,HOMER3,FAM169A,GIT2,RABGAP1L,EXOG,GNE,DTNA,EFNA3,MRNIP,ERCC2,EZH1,AFF2,HBS1L,SRCAP,MALT1,TXNL4A,CACFD1,ELOVL5,MAP4,ADAM22,NF1,RETREG2,PPP5C,ZSCAN32,PTPRE,RALGDS,RGS12,ZNF821,SMTN,LIMCH1,RBM34,SYT5,ARHGEF12,UBE3A,ZBTB14,EVI5" Drug 6730_DN Rolipram [61413-54-5]; Down 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AMPD3,CDC14B,ARHGDIG,SCAPER,CACNA1I,BTRC,PLEKHB1,DNAJB5,PDE4DIP,CNTNAP2,RIMS3,SPOCK3,EXOG,SIDT2,AASS,ING4,ZNF589,ZNF44,B4GALNT1,SRCAP,POLL,TDRKH,GRM8,GUCY1B1,KCNN1,ZNF862,NEUROD1,PBX1,SERPINI1,PLCD1,GRAMD1C,PID1,RALGDS,FAT4,REV3L,ATXN7,LHPP,SAMSN1,MAPK8IP3,RPGRIP1L,TIAM1,HIRA,PRDM2,EVI5,KCNAB1,NUP214" Drug 4814_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADCY6,PPFIA3,ARHGDIG,ADAM15,SCARB1,DCTN1,SMG7,DNM2,TOM1,SORBS3,EZH1,BAIAP2,ZNF276,BTN2A1,ELOVL5,IPO5,MAP4,MAPT,MATK,MBD1,SLC11A2,ODF2,SSH1,RETREG1,PLEC,PPP5C,SYTL2,RAB5B,RGS10,ROM1,SH3BP2,ITSN1,ABLIM3,SLC6A8,BTBD7,INTS9,PHLDB1,IQCE,AHCYL2,CHST8,BEX4,CABIN1,TPD52,CADM1,UBTF,KLC2" Drug 310_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HG-U133A" Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,ALAD,SPOP,AMT,PKP4,KCNAB2,PDXK,ARRB2,ATM,TJP2,RIMS3,DRP2,EFNB3,EFEMP1,FGFR1,NBEA,B4GALNT1,RUNDC3A,GLS,RAB40B,GRIN1,BTN2A1,AGBL5,KHK,STMN1,PTOV1,NUCB1,PLCD1,PYGM,RIPOR1,ARID4A,ARHGEF10L,RNF220,TCP11L1,PAQR6,FOXRED2,FERMT1,SMARCC2,CDK5RAP2,SP2,ZSWIM8,TSPYL2,PRRC2C,WASHC4,TNS2,MPPE1" Drug 7233_UP Isopyrin hydrochloride [18342-39-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ACTN2,SLC4A4,NRP2,SCAPER,CACNB2,HAP1,ARHGEF2,SLIT2,TPP1,COL9A3,CSF1R,INTS1,HIPK3,CEND1,KIAA1109,TPK1,HBS1L,USP19,GLYR1,TDRKH,GRM8,ELOVL5,ITPKB,KCNH2,KCNJ3,LSS,MAN2A2,MSI1,NF1,NTRK2,MAPK8,PEX5,RAD51D,FAM184A,RGS12,FRMPD1,SYBU,SLC2A5,ZC3H13,MAPK8IP3,TPM1,TPM2,TRIO,PLPPR2,LAT2,FAM13C" Drug 632_UP "novobiocin sodium, USP; Up 200; 100uM; SKMEL5; HG-U133A" Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,ADD2,SPOP,BEGAIN,CDC42BPA,PKP4,DGKD,MARK4,WASF1,SPAG9,CNTN1,LETMD1,CHD1L,FEZ2,DCAF8,B3GAT3,BSCL2,FGFR1,ATP2C1,GRM8,RBPJ,IL6R,MATK,MPP2,NFE2L2,NNAT,PALM,PDPK1,MED1,RAB3IL1,MYH14,FAM102A,PEX26,FAM214B,CAMTA2,GANAB,WASHC4,AHCYL2,BEX4,TP53BP1,SMUG1,TRPM2,CADM1,UBE3A,JMJD1C,RNF146" Drug 2060_UP Amidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "MTUS1,AMPD2,APBB1,APBB2,APP,MARK4,ADAM23,MTMR2,ARHGEF1,SYNGR3,CLCN3,NMT2,DNAJB5,NIPBL,IQCK,ABI3BP,LYPD1,PLPPR4,DLG3,DPH1,EFNA3,FAM13A,MBNL2,ING4,VPS26C,GPER1,KIF5C,TAGLN3,MX1,PTHLH,PTPN13,PTPRN2,FAT4,GTDC1,NEK11,CSRNP3,KDM4D,FNBP1,KDM4C,CAMTA2,KIAA0930,ZNF34,EMSY,FZD3,MARCH8,ACTR3B" Drug 3305_DN Cisapride [81098-60-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,ARRB2,NCOA1,NUMB,CFLAR,ARHGEF2,VAX2,ENTPD4,ABCG1,CSNK1E,LYPD1,DLG3,KIAA1109,BAIAP2,FAM49B,SRCAP,ZNF276,PRRC2B,CACFD1,GIT1,NPTX1,NUMA1,PDE3B,LRP12,GON4L,ZSCAN2,RAD52,RGS10,ABLIM3,PREX2,SLC6A8,BTBD7,UNC5B,NCDN,ELOVL4,STX1A,SUPT5H,ATP11A,TBL1X,ZNF34,TIAM1,KAT6B,PLPPR2,ZNF45,WNK1,EPM2A" Drug 1624_UP Clofazimine [2030-63-9]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,ADD2,C1QTNF1,APAF1,AQP6,RASL11B,ATP2A2,CFLAR,BMP7,CFAP410,CAST,CCNT1,KCNAB3,SLC4A7,C2CD2L,SMG7,DNM1,DTNA,EFNB3,EPB41L2,SPACA9,GSTM5,TJAP1,MX1,LYRM9,NF1,OMG,CCSER2,KCTD15,PLEC,LRP12,CNNM2,RALGDS,ATXN2,NTNG1,BCAN,KDM4B,NCDN,DMXL2,TCF7L2,PHF24,TNS1,WBP2,NR2C2,SMUG1,CADM1" Drug 2647_UP Fusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "TRMT9B,AMPD3,APBB2,ARRB2,ALDH4A1,BCL2L2,CACNB2,CLGN,AKAP7,LRIG1,CTNND2,HDAC4,CTIF,MFAP3L,SMG7,HS3ST2,DTNA,MAMLD1,PHF20L1,DENND4A,PRKAG2,DLL3,ALDH1L1,RAB30,GLS,GRM1,MKLN1,PGAM2,STRN3,PTAFR,RGS10,KCTD17,ZFHX4,SYNDIG1,FAM214B,TNIK,KDM4C,PEG10,ARHGAP26,SPTAN1,ELOVL4,TCF4,ZNF34,UCHL1,SLC30A3,EVI5" Drug 2238_UP Pindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "PLA2G6,ATP1A3,RGS11,CACNA1G,BTRC,CACNG1,CAMK2B,CHM,TAOK2,QKI,SULT4A1,DRD1,ATN1,AASS,FGFR1,FGR,FOXG1,AGAP2,SORBS1,MSL3,GNG3,ADAMTS13,PTGDR2,HPSE2,IGF1,IL6R,KCNQ3,SMAD1,MEF2C,MX1,NPPA,PDGFRA,GPR85,CEP41,KLHDC8A,RASA3,ASAP3,SLC9A5,SOX2,ZNF423,AJAP1,VAMP1,KIAA1107,AP4E1,CLIP2,ADAMTS9" Drug 2276_DN Flumequine [42835-25-6]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NME5,C1QTNF3,AMPD3,PPP4R4,ARRB1,PLA2G4C,MARK4,CADM3,SYNJ1,CAMK2B,RUNX1T1,SLIT2,QKI,EDNRA,EFNA3,PLXNC1,ZNF589,FER,AGAP2,TPK1,SRCAP,AHDC1,MSL3,GNAS,GNG4,KCNH2,MMP16,ADAM22,PLCD1,POLG,MAPK10,RAB3IL1,ZDHHC14,ARHGEF10L,GSTCD,TCP11L1,CXXC4,TROVE2,CLSTN2,VAMP1,PSD3,AP4E1,SLC30A3,WNK1,DNALI1,KCNAB1" Drug 4785_DN Idoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "SLC12A5,AP2A2,MAP4K3,ALDH4A1,CFLAR,FUBP1,SCAPER,KYAT1,LRIG1,PDE4DIP,SDC3,DCAF8,DCTN1,MFAP3L,MRNIP,EZH1,CAMSAP1,FHL1,GAD1,MSL3,GNG4,CACFD1,DHX35,NFYA,ODF2,PDE4A,PLEC,FSD1,MINDY2,TMEM231,RAD52,RGS10,SH3BP2,AMBRA1,EPN2,BTBD7,LIMCH1,PDZRN3,SOX2,ZHX3,CAMTA2,ASTN2,ANKRD12,CADM1,VAV1,SMIM8" Drug 833_DN 5255229; Down 200; 13uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "CLK4,ADD3,ARRB1,REPS2,CLCN3,ARHGEF6,ZNF337,SMG7,G3BP2,DTNA,PHF20L1,STX2,VPS26C,EFEMP1,BAIAP2,TRMO,ERAP1,INPP5K,COPS8,SPIN1,SLC2A6,KCNJ3,MATK,NFYA,SETD4,NLE1,PLEC,FA2H,PPP5C,PRKAB2,RGS12,FOXRED2,NUBPL,EMC1,SS18,FCHO1,CEP68,MTCL1,TRIM2,ARHGEF12,THRA,TMPO,UBE3A,PRDM2,MPPE1,PHTF2" Drug 5056_DN L(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "RALGAPA1,BRAP,ALDH7A1,BCL2L2,MYRF,MAP7,SLITRK5,ARHGAP24,EXOG,DPH1,ATN1,HIPK3,MBNL2,ACSL4,ZNF589,BAIAP2,FOXG1,PDLIM5,CGREF1,NCKAP1,GART,USP19,CNTRL,RASSF8,MEF2C,SLC11A2,PBX1,PTHLH,FAM120C,RAD52,RGS4,TCP11L1,MAPK12,COA1,TMCC1,SP2,NXT2,TTBK2,VAMP1,GPR161,TK2,SSBP2,OSBP2,SPHK2,EVI5,UBE3B" Drug 4062_DN Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "MRTFA,BIN1,ANK3,APBB2,SEMA4G,PPP4R4,ADAM23,NRP2,CACNA1I,MYRF,FOXN3,DNAJB5,RAB26,WHRN,NCOR2,PPP6R2,DAPK3,EFNA3,DMTN,MTSS1L,ERCC2,FGFR1,GAB1,GPER1,SHISAL1,JAK2,KIFC3,MATN3,MYT1,CNOT4,OPCML,PIK3R1,RETREG1,PID1,ZFP30,ANKRD6,PPP4R3A,TNIK,UNC5B,CAMTA2,SYN2,ASTN2,ATP11A,EXOC7,VIPR2,LAT2" Drug 2458_DN Cefotiam hydrochloride; Down 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,ADRA1D,KIDINS220,ALK,AMPH,CDC42BPA,FAM131A,SEMA4G,MYRF,LDLRAD4,AKAP7,RUBCN,EFNB3,CELSR3,RASGRP2,CDKL3,FOXG1,ZNF276,CRCP,MSL3,KIF5C,MDM4,MPP2,NF1,NFYA,PDE1C,MAPK10,CNTLN,RAB3A,RAD52,ZCWPW1,ZDHHC14,FOXRED2,ZNF821,SLC1A7,SNCA,KDM4B,SPTAN1,IQSEC2,TSPYL2,RAP1GAP2,FCHO1,STX1A,LMF1,EVI5,GDPD5" Drug 2512_UP Anabasine [494-52-0]; Up 200; 24.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ALK,ASPH,CCDC181,ATP1A3,CADM3,BAIAP3,TMEM257,CHRNB2,CLCN4,NRXN2,DNAJB5,CRMP1,PHYHIP,DTNB,ST8SIA3,AASS,TNK2,COQ7,DMTN,GLS,GPR19,STON1,HTR2A,KCND3,MN1,NDUFA5,NEUROD2,NFIX,NOS1,PIK3R1,ELOVL2,SEC14L1,SMTN,SLC6A9,IZUMO4,TACR1,DNMBP,WSCD1,TCF7L2,PCDHGA10,TRPC1,SSBP2,VAV2,VSNL1,KCNK12,SLC17A7" Drug 4116_DN Cefotetan [69712-56-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AK2,CDK10,ARHGDIG,SLC2A11,KRIT1,SOCS6,STOML1,ATN1,DSCAM,PRKAG2,CGREF1,RUNDC3A,GLYR1,PCLO,CNTRL,ELOVL5,ITIH2,MATK,MBD1,MDM4,MITF,MPP2,ADAM22,SERPINE2,MTRF1L,PLPPR1,ELOVL2,RIPOR1,RALGDS,CARF,FBXW7,MAPK12,ZNF821,PPP4R3A,TROVE2,ITPRID2,PLCB1,PDLIM2,ARHGEF12,CHST8,PARD3,CABIN1,RUNDC3B,VAV2,EVI5,SEMA3B" Drug 2771_DN Convolamine hydrochloride [500-56-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AMPD3,APOC1,APP,KIF1A,RUNX1T1,ASIC3,B4GALT6,DNAJB5,CSF1,ARMCX2,JAKMIP2,MFAP3L,DSCAM,EFNB3,SORBS3,NCALD,SEMA4D,GPR153,DISC1,AHDC1,GLS,CACFD1,ICA1,KCNN2,MITF,GIT1,ADAM22,SLC11A2,PLCD1,PLXNB1,MAPK7,RAD52,RGS10,RNASEL,SH3BP2,SLC6A8,BTBD7,WDTC1,ZC3H13,PLCB1,PSD3,TNS2,CABIN1,ZKSCAN5,MAP3K12,ST7" Drug 1326_DN "Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BRAP,APAF1,APBB2,BCL7A,ARHGEF7,ENTPD6,AP4M1,CLTB,IQCK,RNF14,OSBPL3,TM9SF4,DBN1,SPATA2,GSDME,PCOLCE2,BSCL2,ANKFY1,PDLIM5,HBS1L,AHDC1,LILRA2,TJAP1,LIG4,MATK,NAP1L1,NF1,NFYA,SETD4,ODF2,PTPA,SIDT1,RAD51D,RET,RGS10,GSTCD,NUBPL,ARHGEF40,PDLIM2,TCF4,PARD3,LAT2,XRCC4,ZNF142,FTSJ1,ACTR3B" Drug 4277_DN Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "PKP4,NFS1,KYAT1,KRIT1,ARHGEF2,SRSF11,SOCS6,CHN2,HOMER3,CPS1,DZIP3,APPL1,ARMCX2,ING4,DENND4A,VPS26C,ATP8A1,FCGRT,POLL,GPR37,BACH2,IL11RA,ARHGAP12,PALM,PDE1C,PDGFRA,PFKFB2,STRN3,LRP12,SCG5,SMARCA4,LIMCH1,KDM4B,PDZD2,SPTAN1,SS18,PLCB1,SYT1,ASTN2,MICAL1,XRCC4,WNK1,EVI5,HPS4,KCNAB1,UBE3B" Drug 7299_UP Iobenguane sulfate; Up 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BIN1,KCNAB2,MTMR3,ARHGAP33,CHI3L2,WHRN,AKAP5,IFFO1,PLCH2,TOX,DNAJC6,MFAP3L,EDNRA,OGA,GAD1,HBS1L,SYT17,STON1,KLF12,SMAD1,CCSER2,PRPH,GAL3ST4,SEC61A2,MYH14,SCN8A,FAM102A,AMBRA1,SLC1A7,PPP4R3A,RAB3GAP1,SNCA,TMCC1,SOX2,KIF21B,TSNAXIP1,KDM4C,SYT11,KAZN,RPGRIP1L,OBSL1,TRIO,TRPM2,WIPF1,UPF3A,EPM2A" Drug 7200_DN Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,MTUS1,BIN1,EPB41L5,PPFIA3,ATM,ATP6V0A1,ST3GAL5,FOXN3,ZFYVE9,PICK1,SLC4A7,SH2B1,CSNK1E,SDC3,CTH,GREB1,C2CD2L,PARD6A,DLG3,MED12,DTNA,EIF4G2,SORBS3,ZNF589,AFF2,OGA,GLYR1,MSL3,BTN2A1,ARHGAP19,INPP5B,GIT1,ADAM22,NF1,NRGN,PAQR6,ASAP3,AMBRA1,PEX26,MAPKBP1,ZBTB43,TROVE2,TCF7,TRPC1,GAN" Drug 1824_DN Atracurium besylate [64228-81-5]; Down 200; 3.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APP,MADD,ALDH4A1,ADAM15,CFLAR,CA12,SCARB1,AP4M1,CSF1,VCAN,TBC1D5,DAPK3,SGSM2,EDN1,EFNA3,EN2,VPS26C,WAC,FHL1,NOP56,PDLIM5,INPP5K,SRCAP,AGFG1,NFYA,NPR2,ODF2,OGG1,PDPK1,KCTD15,PLEC,POLG,ELOVL2,DCUN1D2,SAFB,RAB3GAP1,SIRT2,ELMO2,IFT122,SS18,SYT1,FAM155A,PLPPR2,UPF3A,PRDM2,URM1" Drug 6083_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABHD6,ARID1A,AP2A2,NME5,C1QTNF3,BCAS1,ALDH4A1,SLC4A4,ATP6V0A1,GYG2,CA4,HAP1,CBFA2T2,FOXN3,ZFYVE9,QKI,AKAP7,SIPA1L1,PDE4DIP,RIMS2,MAML1,DTNA,C3orf18,KIAA1109,FGF12,POLL,GNG3,DHX35,INPP5B,KPNA5,ADAM22,MAPK7,PRODH,RGS3,SEMA6D,ZNF365,SMARCD3,KIF13A,UNC5B,MAPK8IP3,SYN2,HEY1,TPD52,TPM1,VAV2,WIPF1" Drug 1392_UP Pindolol [13523-86-9]; Up 200; 16.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA3,AMT,APBA2,APP,BMP7,MTMR3,SLIT2,PLAA,HINFP,SOCS5,CTH,DAPK1,ZEB2,FEM1B,MRNIP,EPB41L2,KIAA1109,AGAP2,ATP2C1,LYVE1,GLS,NXPH3,KTN1,MARK3,MBD1,SETD4,PPM1B,MAPK10,CNNM2,GON4L,PTX3,RAB3IL1,SATB1,SH3BP2,BTBD7,ZKSCAN3,SPART,LARP4,SS18,FCHO1,TTBK2,FAM208A,WWC1,ZMAT3,TMPRSS5,VGF" Drug 161_UP (+/-)-verapamil hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ARID1A,SEMA6A,ALCAM,SEMA7A,CNTNAP1,KCNAB2,PRX,AZGP1,SCAPER,CACNA1I,RAB29,CACNA1D,AP4M1,FOXN3,EPS15L1,NIPBL,CNTFR,SH2B1,CRMP1,NCOR1,DLG3,SUGP2,EGR3,ETV1,C1orf61,SRCAP,CRCP,BTN2A1,CLASRP,ATXN2L,CNOT4,NPPA,NRGN,NTRK3,OXTR,PACSIN1,CNNM2,PTN,CRTAC1,ATP10B,POGZ,PHLDB1,TAC3,SEMA4A,VIPR2,ST7" Drug 6189_DN thioridazine hydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADD1,MTUS1,AGT,MRTFA,AMT,FAM131A,APP,KIF1A,BMP7,SYNJ2,CAPN3,CHRNB2,RAB33A,SLC4A7,CPS1,CTIF,DBN1,ST8SIA3,ERCC2,FOXG1,PRELID3A,GAA,GNG4,SMAD1,MAP4,MEF2C,NLE1,ST6GAL1,DZIP1,NUBPL,SLC20A2,TMCC1,DDN,KANK1,KAZN,WWC1,CUX2,SZT2,PSD3,THRA,PARD3,TNNT1,TNS1,VIPR2,ZNF23,TFIP11" Drug 3314_DN Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,NME5,APP,ALDH4A1,GYG2,CA4,CLGN,FADS2,DNAJB5,SDC3,PPP6R2,RUSC2,RCAN1,CNNM1,FHL1,GPR153,HBS1L,RUNDC3A,GLYR1,RAB30,ITPKB,KCNN2,MAN2A2,GIT1,NEK1,NF1,NPTX1,NLE1,SIDT1,TMEM104,ZSCAN32,RAB3A,FBXW7,MAP6D1,FAM214B,SLC6A8,SLN,SMARCD3,ERC1,UNC5B,NXT2,PLCB1,IQCE,EIF4ENIF1,VGF,SMIM8" Drug 3722_UP Tropicamide [1508-75-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASPHD1,KLRC4,ALAD,LTBP4,AQP4,RASL11B,NRP2,CDK5R2,CACNG1,USP2,TAOK2,RAB26,IFFO1,CREM,CNTNAP2,RIMS3,TRAPPC9,DSCAM,SEMA3D,RGS17,RASGRP2,KIAA1109,GAB1,GAP43,GFER,GFRA1,GPR19,NNAT,PALM,CDK18,PDE2A,PPP2R2B,RGS3,RGS4,DZIP1,PKNOX2,SLC11A1,ZNF334,ARC,KAZN,OBSL1,TK2,CDK20,UCHL1,SPHK2,KCNAB1" Drug 5485_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "C1QTNF3,EPB41L5,ATP2B1,BCL7A,ST3GAL5,MAP7,KYAT1,STOML1,QKI,CREM,ABCG1,MICAL2,PDE4DIP,DCAF8,KIAA0753,DSCAM,SIDT2,MRNIP,COQ7,DENND4A,ANKMY1,INPP5K,GPR19,MAP4K5,JAK2,KHK,KIF2A,NF1,OGDH,SLC25A23,RC3H2,PRPH,GTDC1,LGR4,WLS,ATXN1,SHANK2,MAPKBP1,TMCC1,MAPK8IP3,SEPT8,TACC1,AHCYL2,SMUG1,PLPPR2,VPS35L" Drug 1782_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,CADM3,GYG2,CA12,CHN2,EPS15L1,RAB26,CRMP1,PPP6R2,ZNF337,DAPK3,DCT,EXOG,EFNB3,KAT8,BAIAP2,TRMO,POMT1,PCDH17,CACFD1,NXPH3,ATXN2L,TJAP1,KIF5A,LIG4,NF1,NRCAM,NTRK3,SETD4,OLR1,PTPA,DEF8,RGS12,RNASE1,NTNG1,FNDC3A,CCDC92,SLC11A1,KBTBD4,ELMO2,TEX2,ARHGEF12,PCDHA5,TRPM2,CAMK1G,NLRP3" Drug 1962_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; PC3; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ACLY,PKP4,APLP1,CANX,KRIT1,TBRG4,PLAA,CLU,NIPBL,ZNF337,G3BP2,DPH1,DTNA,APH1A,ACSL4,FGF1,FHL1,PCYOX1,B4GALNT1,SRCAP,C1QL1,RNFT2,HPS5,MAP4,PPM1B,RAB3IL1,RAB5B,NUDT11,DOCK10,RAB3GAP1,INTS9,ZHX3,TSPYL2,NXT2,PRRC2C,ARHGEF12,ATP13A2,HEY1,PARD3,SEZ6L,TPM4,PLPPR2,URM1,NAV2,SNX27,SMIM8" Drug 1300_UP "Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "MTUS1,APP,CDK10,EIF4G3,ATP6V0A1,BCL7A,SCAPER,SGCE,KYAT1,CHN2,ZFYVE9,CLCN4,STOML1,SLITRK5,PPP6R2,GAA,ERAP1,CRCP,GPR19,KCNJ5,GIT1,NFYA,CNOT4,SLC11A2,NUMA1,PTAFR,PTCH1,RAB3A,RAP1GAP,TCP11L1,SLC12A2,ARFGAP1,TMCC1,RBM26,ST5,KANK1,MLC1,SUPT5H,PSD3,ARHGEF12,KAT6B,TPD52,FLRT2,PDSS2,UBE3B,KAT6A" Drug 3112_DN "(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BIN1,APOC1,MARK4,ADAM15,MTMR3,B4GALT6,CLCN4,KIAA0753,RBM12,TNK2,NCALD,KAT8,GAA,INPP5K,MSL3,GRM1,ATXN2L,LAMA2,MAP4,AFDN,N6AMT1,NINJ2,OGG1,P2RY1,PFKFB4,PLCD1,PLCL1,TMEM104,PTAFR,SBF1,PPM1E,AMBRA1,SLC1A7,KDM4B,WDTC1,KDM4C,SPTAN1,IQSEC2,ZC4H2,JMJD6,KAZN,PSD3,FLRT2,LMF1,ATP6V0E2,NT5M" Drug 7034_DN Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADD3,CDC42BPA,DGKD,FAM131A,ALDH4A1,BCL7A,CDH10,IQCK,ARMC8,ARHGEF10,PDE4DIP,DZIP3,GIT2,C2CD2L,LYPD1,MED12,DNM2,EFNA3,MBNL2,MRNIP,FOXG1,MSL3,GNG4,KHK,ADAM22,NFYA,FSD1,NKAIN1,RAD52,CCDC25,SGK1,FNDC3A,ABLIM3,PPP4R3A,SMTN,BTBD7,TMCC1,IQSEC2,ZBTB43,SPART,MAPK8IP3,ELOVL4,EXOC7,WWC1,TRPC1,UBTF" Drug 5003_UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,ADCY2,BIN1,RGS20,KCNAB3,CHRNB2,DNAJB5,PICK1,SPOCK2,CTIF,SMG7,HIPK3,MBNL2,OLFM1,FGF13,CAMSAP1,AGAP2,SEMA4D,EFCAB2,SORBS1,FYB1,HBS1L,PRUNE2,STON1,IRF8,INPP5B,KCND3,KCNN1,KIT,PLEC,EPN1,SPATA6,PLPPR1,PBRM1,TCP11L1,RPS6KA2,EMID1,S100B,PKNOX2,RIMS1,SOX10,TBCEL,DOCK9,TRPM2,HIRA,NLRP3" Drug 5874_DN Praziquantel [55268-74-1]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BRAP,KIDINS220,APBB2,CDC14B,MARK4,ALDH7A1,SOCS6,TAOK2,ZFYVE9,CLU,NRG2,VCAN,DCAF8,DBN1,DBT,ZNF804A,ING4,MFSD10,COQ7,ATP8A1,BAIAP2,FHL1,GBX2,PRRC2B,IFI16,DIPK1A,MAP4,SCAMP5,MITF,ZNF862,MAPK3,PTCH1,PTN,RIPOR1,PAQR6,WDR37,TSPYL2,TROVE2,POGZ,SYT1,KAZN,WWC1,TRIM2,NPDC1,WNK1,EMSY" Drug 6226_UP "Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ACTN1,AK2,C1QTNF1,TRMT9B,CDK13,CFLAR,CDK5R1,BTK,MTMR2,CA4,CACNA1A,CACNA1D,SOCS6,CHRNB2,CLCN3,CPS1,PDE4DIP,SDC3,MFAP3L,DNM1,DMPK,DSCAM,VPS26C,ZNF589,FHL1,GNAS,IGSF1,INPP5B,KCNC1,MDM4,NRGN,SAMD9,VPS13C,C1orf54,ABLIM3,SLC6A8,BTBD7,SLC20A2,ZBTB43,PSD3,AP4E1,TMOD1,OSBP2,ZBTB14,SYNC,SSPN" Drug 7235_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "KIDINS220,AK2,BIN1,CDC14B,ALDH7A1,MPDZ,NRP2,BTRC,CA4,CACNB4,CALB2,ARHGEF2,DNAJB5,ATRNL1,EFNA3,TNK2,IGSF6,DLC1,KIAA1109,SIGLEC8,RND1,TDRKH,GRM8,HNMT,ICA1,TJAP1,LIG4,ADAM22,NF1,CLDN11,PCDH9,NLE1,RGS12,SYBU,SLC2A5,FAM214B,ZCCHC24,RBM26,PHLDB1,ARC,SEMA4A,TRIO,AMACR,XRCC4,SSPN,SENP7" Drug 370_UP troglitazone; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "RBM10,NDRG3,C1QTNF1,GAS7,CFLAR,AIFM1,SULT4A1,CNTFR,RCHY1,AATK,ARHGAP32,DLG3,IRAK4,TNK2,FCGRT,TESK2,AFF2,CAMKK2,GPR153,SEPT9,CACFD1,KLF12,VWA5A,ADAM22,MYT1,NTRK3,OMG,PLCB2,PLCD1,MAPK3,RAP1GDS1,RNASEL,INTS9,KDM4B,EMC1,SRPK2,ZC4H2,FCHO1,MCF2L,NSD1,ARHGEF12,ZMAT3,VGF,VIPR2,SLC17A7,MPPE1" Drug 6208_DN Dienestrol [84-17-3]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "CDC42BPA,EPB41L5,SCARB1,SOCS6,CREM,CSNK1E,DCAF8,DBT,SMG7,RABGAP1L,RBM12,MRNIP,SCML2,EFEMP1,DISC1,ZNF276,KCNMB4,FERMT2,PRRC2B,GPR37,KIF2A,MAP4,NFYA,PDE4A,TNPO2,ARID4A,SEC61A2,FAM192A,FOXRED2,FNDC3A,PDZRN3,SPATA7,ERC1,FCHO1,NSFL1C,FAM168A,FBXW11,TBL1X,TCF7L2,PSD3,PARD3,KAT6B,CADM1,VAV1,MPPE1,MARCH8" Drug 5768_DN Hexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ARID1A,C1QTNF1,AMPD3,APBB2,PPFIA3,PDE8B,C5,CHM,ZFYVE9,DNAJB5,AKAP7,SMARCAL1,CPS1,CSNK1E,CNTNAP2,ARHGAP24,CNIH3,FBXL5,RUSC2,C2CD2L,KBTBD11,DLG3,EDNRA,SORBS3,DENND4A,SCARA3,PCDH17,GNG4,TJAP1,KIF5C,NF1,PBX1,MAPK7,PEX5,RAB3A,SUGCT,SBF1,ASAP3,AMBRA1,ELMO2,WDTC1,TMEM121,CHST8,TNS1,ZNF74,KCNAB1" Drug 5258_DN Clioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,AP2A2,APBA2,APC,ARRB1,PLA2G4C,BMP7,GYG2,CA12,BAG4,NOS1AP,EPB41L2,EZH1,EFCAB2,HBS1L,MALT1,GNAS,GPER1,CACFD1,JAK2,MAPT,NF1,OGDH,PDE3B,PMP22,KLK6,RET,SBF1,ITSN1,DHX30,SMTN,PDZRN3,WDTC1,ZC3H13,TROVE2,PLCB1,SYT1,ATP11A,EHBP1,CRTC1,PCDHA6,PCDHA5,CDK20,ZKSCAN5,GDPD5,SSPN" Drug 5272_DN "Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,PLA2G6,C1QTNF3,APBA2,APC,ADAM15,SYNJ2,CBFA2T2,FOXN3,PLEKHB1,CRY2,CNTNAP2,NOS1AP,MFAP3L,SMG7,DRD1,DSCAM,PIPOX,ZNF589,FGF13,PDLIM5,SRCAP,GLYR1,GLS,GNG4,KIF5A,MBD1,RETREG1,PLEC,MED1,PRPH,PLPPR1,ZSCAN32,PEX5,RGS12,ZFHX4,MAP6D1,ZCCHC24,TROVE2,ELOVL4,SEMA4A,AHCYL2,ZNF34,SLC44A1,PARD3,SSPN" Drug 3009_UP Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABAT,CDC42BPA,APC,ARHGDIG,BAIAP3,HIP1R,MAP7,SLC16A4,CDH10,SLC4A8,CRYBB1,NCOR2,DZIP3,RIMS2,RIPOR2,EDN3,HIPK3,SRPK3,RASGRP2,CHST15,KIAA1109,FHL1,SEPT9,GPD1,GSN,GUCY1B1,ATXN2L,SCIN,MDFI,ADAM22,SETD4,PDE4A,RGS4,RGS12,KLHL11,SLC11A1,PALLD,ATP13A2,AP4E1,TK2,TPM2,TPM3,TRPS1,SSBP2,KCNK12,SPHK2" Drug 5424_UP Cefoperazone dihydrate; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,SPARCL1,APP,CDC14B,ADAM23,CA4,CA12,NEURL1,CDH8,DLGAP2,DNAJB5,WHRN,DTNA,EDNRA,HIPK3,KIAA1109,PDLIM5,TBR1,GPR75,PCLO,CNTRL,GRM8,GUCY1A1,TJAP1,ITIH2,KCNN1,MAP2,MMP16,CD200,NF1,PDE3B,PPP5C,PRKAR1B,PTPRD,PTPRN2,FAT4,UEVLD,SORCS3,TSNAXIP1,MAPK8IP3,DOCK9,ZNF34,TIMP4,CDK20,SYNC,PARP11" Drug 7199_DN Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ARID1A,ANK3,APAF1,SYNJ2,USP2,FOXN3,SOCS6,TAOK2,PLAA,HOMER3,PICK1,COL9A2,GREB1,SORBS3,ZNF589,AFF2,OGA,GABRA2,INPP5K,HNMT,MAP4,NUCB1,SETD4,PBX1,PC,RETREG1,PPP3CC,TMEM104,RAB3IL1,RXRA,TMCC1,SPATA7,ZHX3,UNC5B,ZBTB43,SATB2,TNS2,BHLHB9,NR2C2,LMF1,ZNF24,HPS4,EPM2A,UBE3B,ACTR3B,GAN" Drug 6616_UP "Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "PLA2G6,ALK,AMPH,SEMA7A,EPB41L5,GAS7,ATP6V0A1,SYNJ1,MTMR3,CDH10,CNTN1,AKAP5,ENTPD4,CSF1,ARHGEF4,EDRF1,EDNRA,HIPK3,ING4,FGF1,DCTN2,GAD2,ALDH1L1,CYP46A1,PRUNE2,PADI2,C2orf72,MYL3,NCAM1,PIK3R1,PRPH,VPS13C,PTN,PTPRD,CARF,KCNIP1,NTNG1,SNCA,TMCC1,KIF21B,TEX15,THRA,LILRA4,VAV2,EPM2A,DPF3" Drug 5799_DN Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "OGT,APC,MARK4,CDK5R1,SCAPER,CFAP410,HIP1R,MAP7,CLCN4,SIPA1L1,RIMS3,PARD6A,DLG3,DPH1,HIPK3,FEM1B,STX2,IQCG,SRCAP,PCDH17,GPR19,GPR37,GUCY1B1,SHISAL1,KIF5C,ZNF862,NDUFA5,NF1,PBX1,PDGFRA,SMOX,FSD1,PRPH,PTN,PTPRN2,NEK11,ATXN7,SH3BP2,THSD1,ARHGEF9,MCF2L,KIAA0930,HIRA,LMF1,ZNF32,WNK1" Drug 4995_DN Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NME5,ALAD,OGT,APP,SLC4A4,QKI,PDE4DIP,PPP6R2,ZNF337,DAPK3,DSCAM,DTNA,FCF1,PDLIM5,SRCAP,ZNF276,MBD1,MDM4,ADAM22,NF1,NFYA,CNOT4,ODF2,CCSER2,PLEC,PPP5C,PRKAR1B,SYTL2,RAB3A,ZCWPW1,CCDC25,SAFB,EPN2,SCMH1,SMARCA4,EMC1,SS18,STX1A,EXOC7,TCF7L2,TRIM2,TMPO,VGF,LMF1,NSD2,GAN" Drug 3560_DN Methantheline bromide [53-46-3]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "C1QTNF3,CDK10,ASPH,ADAM15,BCL7A,SCAPER,CACNB2,BAG4,SH2B1,PPP6R2,DNM1,EDNRA,NCALD,NOP56,BTN2A1,RASSF8,ICA1,IL6R,INPP1,MBD1,MID1,GON4L,PEX5,RAB3IL1,ATG16L1,FAM184A,WLS,ZNF365,FAM214B,EMC1,ZNF423,STX1A,POPDC3,SEMA4A,TCF7L2,TRIM2,ATP13A2,DICER1,TK2,TPM1,CDK20,TRPC1,XRCC4,TFIP11,SYNC,URM1" Drug 5286_DN Dichlorphenamide [120-97-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APC,CDC14B,ARHGEF7,CNOT8,RAB28,PLAA,FAM169A,PPP6R2,DAPK3,COPS7A,C2CD2L,SGSM2,G3BP2,ATN1,TSPAN5,SH3GLB1,CELSR3,EPB41L1,GPHN,CDKL3,DPYSL4,FAM49B,CGREF1,INPP5K,GLS,MSL3,RNFT2,HSF2,MBD1,NF1,NPR2,SLC11A2,OCRL,PDE3B,PRKAR1B,CEP97,ATG16L1,SGK1,EPN2,SIRT2,ERC1,LHPP,EXOC7,VIPR2,MAP3K12,RNF146" Drug 2013_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ALAD,GAS7,PDXK,NCOA1,ATP2B1,RCBTB2,SRSF11,TAOK2,ZFYVE9,ZNF804A,SMG7,PHF20L1,CD320,EZH1,FKTN,ATP2C1,FYN,TRAF3IP2,SEPT9,GRIK5,ARHGAP19,KLC1,MAN2A2,MITF,NFYA,PTPA,RDX,SH3BP2,BCAN,CCDC88A,MAPKBP1,DOP1A,HECW1,NCDN,MCF2L,EXOC7,WDR7,SIRT1,TK2,TP53BP1,WBP2,CLDND1,ZNF32,ZNF142,SMIM8,DPF3" Drug 1816_DN Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APBB1,APP,ST3GAL5,PLEKHB1,FADS2,SLC4A7,CSF1,SPATA2,CNIH3,KIAA0753,RUSC2,KLHL3,NR1D2,DNM2,TOM1,EDN1,FEM1B,FGF1,DLL3,ERAP1,SRCAP,PRRC2B,MEIS1,GIT1,NEK1,NOVA1,ODF2,CDK14,SSH1,MBOAT7,FA2H,TMEM104,TMEM231,CEP97,SUGCT,AP1AR,SLC1A3,DOP1A,ROBO3,TCF4,WASHC4,BHLHB9,LMF1,WNT7A,PRDM2,HPS4" Drug 2487_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ACTN2,APC,CADM3,KIF1A,CFAP410,CACNG1,RGN,SLC16A4,CDC42,LARGE1,CDO1,NCOR2,CSNK1E,DCAF4,DNAJC6,DCT,LYPD1,EXOG,TOM1,HIPK3,EIF1,STX2,DLC1,AGAP2,NBEA,KHDRBS3,MYOZ2,ADAM28,ATF7,KLF12,JAK2,MOBP,TAGLN3,NNAT,PBX1,PDE4D,POU3F2,RGS12,TTLL7,ASAP3,LIMS2,SNCA,SS18,SYT5,FAM155A,LMF1" Drug 6706_UP Cisapride [81098-60-4]; Up 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA1,PLA2G6,ADGRF5,PPP4R4,RGS11,CACNA1I,THSD7A,CHRNA4,IFFO1,CSF1,PDE4DIP,FRMPD4,DSCAM,DTNB,ING4,NRN1,ZNF589,SIGLEC8,GPR22,GRM8,GUCY1A2,HRH3,HLF,HNMT,ITGA7,KCND3,KHK,BCO1,NOVA2,PFKFB3,MAPK10,PROX1,MARCH1,ZMAT4,KCNIP2,SEMA6D,PKNOX2,KDM4B,IZUMO4,KDM4C,SMG6,TIMP4,TK2,TRPC3,SPHK2,REEP1" Drug 7474_DN Fenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "RBM10,APC,DGKD,PPFIA3,CDK10,MADD,MARCH3,BMP7,LARGE1,EPS15L1,TMEM184B,ARMC8,ARHGEF10,CSNK1E,DZIP3,DCAF8,DBT,ANKFY1,CINP,NFYA,CNOT4,SETD4,ODF2,PLEC,SIDT1,ELOVL2,PTPRE,QDPR,ITSN1,FERMT1,FNDC3A,ABLIM3,SMTN,CDK5RAP2,MAPKBP1,EMC1,ARHGAP26,PHLDB1,ATP11A,TCF7,SIK3,TIAM1,NPL,METTL3,HPS4,GAN" Drug 7307_DN Triamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "APBA2,PPFIA3,ST3GAL5,SCARB1,CNOT8,NRXN3,KIAA1549L,QKI,NRG2,NCOR1,PDE4DIP,SLITRK5,PPP6R2,TBC1D5,DAPK3,ARMCX2,SPATA2,SMG7,RBM12,ATP8A1,PDLIM5,GLI2,GLYR1,EML4,CNTRL,HMGCR,MBD1,NFIX,SLC11A2,PDPK1,TMEM104,ELOVL2,RAB3IL1,MCMBP,ITSN1,KBTBD4,PDZD2,BEX1,SPART,CLASP2,ST5,TMPO,HIRA,MAP3K12,NAV3,FZD3" Drug 7216_DN Repaglinide [135062-02-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BRAP,AP2A2,EPB41L5,CDK13,BCL7A,CDK5R1,SRSF11,LHX2,TMEM184B,CREM,ABCG1,MICAL2,PDE4DIP,DCAF8,FBXL5,SMG7,RABGAP1L,DMPK,GNE,MAMLD1,MBNL2,EZH1,SCML2,PRKAG2,FOXG1,FAM49B,DHX35,MPP2,SETD4,OGDH,SSH1,SMIM7,LRP12,CNNM2,RIPOR1,ATXN1,WDTC1,ELOVL4,ATP11A,KAZN,EXOC7,AGTPBP1,PARD3,ZBTB14,ACTR3B,GAN" Drug 205_DN rofecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADD2,ALAD,GAS7,ARNTL,AZGP1,RUNX1T1,TAOK2,SULT4A1,CNTN1,PCYT1B,AATK,CTIF,ATN1,ING4,PLEKHO1,ERCC2,PIPOX,FGFR1,TRMO,GPR153,NCKAP1,RND1,BTN2A1,SOX21,ARHGAP19,SYNPO,KCNN1,MBD1,MMP16,PLCD1,PTCH1,NKAIN1,RALGDS,CCDC25,ZNF821,FUZ,SLC11A1,SLC20A2,SMARCC2,NMNAT2,EMC1,SSTR2,PHLDB1,COBL,TMPRSS5,ZNF248" Drug 3894_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA1,SEMA6A,AMPH,APAF1,CDC14B,PDE8B,BRINP2,ATP2B2,HAP1,RHBDL1,CDH2,LHX2,AKAP7,AATK,ARHGEF10,IPCEF1,TMCC2,SGK2,EFNB3,C3orf18,EFS,DLC1,FOXG1,ADAMTS13,IGF1,KIT,LAMA2,MGAT3,MMP16,MYO7A,NPTX2,PDE4A,LRP12,NECAB2,MINDY2,TTLL7,SYNDIG1,KCNIP1,CLIP1,EPN2,SLCO1A2,KDM4B,SOX2,DICER1,THBS4,HEY2" Drug 4837_DN "Catechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AK2,SCAPER,CAMK2G,KRIT1,SOCS6,AKAP7,ARMC8,FAM169A,SDC3,CTNND2,KAT8,SEC23B,GAD1,SPIN1,FERMT2,TDRKH,KIF3A,MAP4K5,ARHGAP19,IL6ST,IPO5,MAP4,MEIS2,MSRA,SETD4,RC3H2,RAB3A,PLEKHB2,RGS12,ITSN1,CHD9,BTBD7,SLC20A2,SPATA7,ZCCHC24,CDK19,VAMP1,ARHGEF9,TACC1,IQCE,SATB2,TCF7L2,TSN,KAT6A,SMIM8,GAN" Drug 3897_DN Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NME5,APC,GAS7,CDK13,MARK4,BMP7,HIP1R,SH2B1,NCOR2,MICAL2,DRD1,MBNL2,EGR3,SORBS3,GPR153,GAB1,GCNT2,RND1,CACFD1,ATXN2L,IL6R,MAOB,MAP4,NF1,NPPA,NPTX1,NUMA1,PLCD1,TNPO2,PPP5C,MAPK10,RASA3,DOCK10,SLC9A5,LIMCH1,KIF13A,IQSEC2,PLCB1,ATP11A,AHCYL2,SLC44A1,THRA,HEY1,ZKSCAN5,SYNC,EMSY" Drug 2200_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ABHD6,MTUS1,ANK2,APOC1,MYRF,INA,CBFA2T2,CDH10,LARGE1,SOCS6,VCAN,GPRASP1,HIPK3,PLXNC1,EIF1,RASGRP2,RRAGB,F5,PTK2B,CSPG5,GALC,IL6ST,MAP4,MEF2C,AFF1,GIT1,SLCO1C1,CNOT4,OXTR,PDE4D,MAPK8,RIPOR1,TCP11L1,MAP6D1,LIMS2,ZNF667,ZCCHC24,CAND2,SPTAN1,DDN,JMJD6,PSD3,ZNF34,RBFOX2,TPM3,ZMYND8" Drug 2743_UP Stachydrine hydrochloride; Up 200; 22.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ALCAM,BIN1,APBA2,APOC1,APP,EIF4G3,GYG2,BTRC,CAMK2G,HOMER3,SLC4A7,SH2B1,KBTBD11,EGFR,EGR3,ING4,FHL1,NEU3,RND1,NAP1L2,SERPINE2,SLC25A23,PMP22,STRN3,RAD52,REV3L,KCTD17,GSTCD,RPS6KA2,STUM,FBXO11,URGCP,ZCCHC24,SPTAN1,CAMTA2,RGL1,TACC1,KIAA1107,CHST8,TRIO,UCHL1,ZNF45,ZNF74,NDRG4,MARCH8,KAT6A" Drug 4949_DN Naphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA2A,ADRA1D,CDC42BPA,DGKD,APP,KIF1A,CACNA1D,TAOK2,AKAP7,TRAPPC9,EDNRA,SORBS3,FGFR1,FHL1,DISC1,POLL,PCLO,GRIK5,CACFD1,ITPKB,IPO5,MSI1,ADAM22,NEK1,NRGN,SETD4,PDE4A,MBOAT7,MAPK7,PRPH,PLPPR1,PEX5,RAB3IL1,FOXRED2,PREX2,SMTN,SLC6A8,ZBTB43,EXOC7,TRIM2,RPGRIP1L,PCDHA6,SLC44A1,UBTF,VIPR2,ZNF74" Drug 3172_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADD2,AMT,KCNAB2,APLP1,CDC14B,SYNJ1,GYG2,CACNA1I,B4GALT6,NMT2,SLC4A8,NOS1AP,DBT,DTNA,SEMA3D,EFNB3,TNK2,C3orf18,OLIG2,ETV1,FGFR1,SCARA3,AGAP2,FLT1,GPM6A,TDRKH,GPR37,GRM8,NEUROD1,PDE4B,CCDC102B,ASAP3,MYT1L,SZT2,PHF24,OBSL1,AP4E1,TGFBR3,HEY2,RIMBP2,PIK3R5,TRPM2,VAV2,WIPF1,ZIC3,MVB12B" Drug 3900_DN Ergocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,AP2A2,DOC2A,APC,FAM131A,BAIAP3,CBFA2T2,LHX2,CLU,PICK1,CTIF,SMG7,ING4,ZNF589,SCARA3,DLL3,ELOVL5,ITGAM,KHK,VWA5A,MAN2A2,MID1,BCO1,NF1,NPPA,NPR2,OXTR,PRKCB,MAPK8,GRAMD1C,ZSCAN2,RAB3IL1,FAT4,RXRA,ASAP3,DOCK10,SLC1A7,SNCA,PLCB1,DAAM2,VIPR2,ZFP37,SYNC,EMSY,ITM2C,PHTF2" Drug 1467_UP Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "BEGAIN,AMH,ANK1,APLP1,ALDH4A1,CDK5R1,GYG2,BTRC,CACNA1D,CACNA2D2,PPP6R2,NOS1AP,RIMS3,GIT2,DSCAM,HSD17B14,TUBB4A,FGFR1,HPCAL4,SEMA4D,SRCAP,AHDC1,GFAP,GLYR1,GLS,GNG3,GPM6B,CACFD1,KCNH2,NF1,NPPA,CDK18,CDIP1,POLG,PRODH,SIDT1,CEP97,ZFHX4,FBXO11,KIF13A,ARHGAP26,MAPK8IP3,KIAA1107,ZNF189,KCNAB1,NUP214" Drug 6582_UP AG-028671 [847803-03-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADCY6,BIN1,APC,RGS20,MTMR3,EPS15L1,HOMER3,SIPA1L1,DZIP3,GIT2,CNIH3,SRGAP3,DMPK,APH1A,IRAK4,ING4,RGS17,EN2,PLEKHO1,F8,FKTN,TESK2,FGF1,TMEM164,ARFIP1,GPM6B,GPR17,GRIK5,NR3C1,HPSE2,TM6SF1,NFYA,PALM,PPP5C,CNTLN,RAB3IL1,ARHGEF10L,CSRNP3,ATXN7,WDR47,FAM214B,BTBD7,SLC20A2,EXOC7,KIAA0930,CDK20" Drug 3908_UP CP-320650-01 [172079-28-6]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ASIC1,APOC1,DNAH17,ALDH7A1,NRP2,RHBDL1,CCKBR,SEPT7,CBARP,SLC22A6,CNTN1,CRY2,ST18,DNAJC6,CDON,EFNB3,PLXNC1,GAB1,GLYR1,GPER1,PTGDR2,BACH2,HTR2A,KCNB1,KIFC3,MGAT3,MMP16,MSR1,OMG,CDK18,C19orf57,CCDC40,KCNIP1,ASIC4,NTNG1,SLA,SOX2,SPTB,NPAS3,ATP10B,MAPK8IP3,TEX15,HIRA,VIPR2,XRCC4,SLC30A3" Drug 5790_DN Tropine [120-29-6]; Down 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,APC,PDE8B,ALDH4A1,MTMR3,CLTB,AKAP7,CSF1,CSF1R,GPRASP1,SMG7,DLG3,SCML2,POMT1,PCDH17,GNG4,GPR19,CNTRL,SHISAL1,TJAP1,INPP5B,MMP16,GIT1,LYRM9,ZNF862,NF1,PAK3,PBX1,FAM184A,BEND5,SBF1,ATXN7,IL17RB,ASAP3,BTBD7,KDM4C,SPTAN1,CEP68,SYT1,KIAA0930,TPM2,TRPC1,HIRA,FAM155A,TRIM9,SCG2" Drug 4790_UP Pepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA1,SPARCL1,AMPH,CDC42BPA,PPFIA3,SLC4A4,SLC2A11,CACNA1G,BTRC,FOXN3,IPCEF1,CNTNAP2,PHYHIP,MAGI2,EFNA3,EFNB3,MBNL2,ACSL4,AGAP2,GABRA2,GPR75,GLS,HPSE2,C2orf72,INPP1,KCNC1,KCNH2,NHLH1,PMP2,RAB3IL1,RGS12,PPP1R9A,FRMPD1,SLA,LIMS2,ZNF423,VAMP1,ZEB1,TRIM2,TK2,AMACR,TRO,SSBP2,TUBB1,FAM155A,SCG2" Drug 4722_DN Merbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "SEMA6A,BCAS1,KIF1A,MTMR3,CBFA2T2,ARHGEF2,REPS2,SLIT2,SH2B1,CRY2,ARHGEF4,EDRF1,DCAF8,DAPK3,EDNRA,CNNM1,AASS,HSD17B14,LRRC23,VPS26C,ACSL4,FYB1,TDRKH,INPP5B,KPNA5,MPP2,ZNF862,SLC11A2,TMEM231,RGS10,FBXW7,FAM192A,ITSN1,ANKRD6,RAB3GAP1,SLC15A2,WDTC1,MAPK8IP3,ARHGEF9,ZEB1,TRIM2,WDR7,TRIO,ZKSCAN5,DNALI1,KAT6A" Drug 1719_UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADD3,ASPH,RAB29,ARHGAP33,LARGE1,CNOT8,CLCN3,SEC31B,HP1BP3,KLHL3,ECSIT,SH3YL1,POMT1,OGA,ALDH1L1,MALT1,GLYR1,GABARAPL2,IL11RA,KCNN2,NF1,SLC11A2,ENPP2,PIK3CD,CCSER2,PLCB2,LRP12,MAPK3,PEX2,ARID4A,MSANTD2,RIC8B,TMEM206,KBTBD4,WDTC1,ZCCHC24,ZC3H13,DIP2A,NSFL1C,TAC3,FBXW11,TK2,CABIN1,RBFOX2,ZNF24,CAMK1G" Drug 2910_DN Gibberellic acid [77-06-5]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "AP2A2,ADAM15,BCL7A,C5,SLC25A14,MAP7,KYAT1,ZFYVE9,TPP1,IQCK,PDE4DIP,GIT2,PCOLCE2,TUBD1,SCML2,ST3GAL6,ZMYND11,GART,COPS8,AGFG1,DHX35,MAP4,MITF,SLC11A2,STRN3,PILRA,PTPA,MAPK8,PTPRN2,ZCWPW1,TCP11L1,HSPA4L,DHX30,COA1,TNIK,TSPYL2,FAM168A,SYNE1,AP4E1,PIK3R5,TPM3,ZKSCAN5,LAMP5,ZNF225,MAP3K12,NLRP3" Drug 5983_DN Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "KIDINS220,AK2,MRTFA,APBB2,APLP1,ATM,CFLAR,CSF1R,CSNK1E,CNTNAP2,GREB1,HP1BP3,SGSM2,ZNF589,FGFR1,BAIAP2,CGREF1,GABRA2,CRCP,GRM1,MUM1,MAP4,NF1,NUMA1,CCSER2,PMS2,MINDY2,CNNM2,FBXO11,EPN2,FAM214B,ZNF430,FCHO1,ARHGEF9,CHST8,KCTD2,TRPC1,ZMYND8,HIRA,UBTF,VIPR2,ZFP37,UPF3A,WNK1,HPS4,RNF170" Drug 4655_UP Enoxacin [74011-58-8]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "ADORA3,LTBP4,APC,SEMA4G,ARHGDIG,MARK4,SLC4A4,HAP1,ADGRG1,AKAP6,COL9A3,IFFO1,CSF1R,CX3CR1,PLPPR4,DMPK,DRP2,CACNG2,DPYSL4,PRELID3A,B3GAT1,MYOZ2,GPR75,GPM6B,SPACA9,BACH2,KIFC3,ADAM11,MINDY2,LRRN3,CNNM2,ENOX1,SLC6A15,KCNIP1,CPEB3,SLC12A4,ZNF334,SPTAN1,SAMSN1,SSTR2,PHLDB1,TLR4,RUNDC3B,PRDM2,SCG2,EPM2A" Drug 2428_DN Biotin [58-85-5]; Down 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.55E-03 1.00E+00 2.00E-02 2.28E-01 46 198 "NDRG2,ADORA3,MRTFA,AMH,PPFIA4,PKP4,APP,SLC4A4,KRIT1,PLAA,CLCN4,NMT2,CLTB,IQCK,PPP1R16B,RUSC2,DTNA,FAM13A,LRRC23,CAMSAP1,GABRA2,MAP4K5,MEF2C,ZNF862,NUCB1,PDE4B,SLC25A23,RC3H2,PEX5,RAB3IL1,ATXN2,GALNT10,FUZ,ANKRD6,EPN2,SMTN,ARHGAP26,TROVE2,FAM168A,PDLIM2,ZEB1,SYNE1,OBSL1,PARD3,KAT6A,TIGD6" Drug CID000002388 AC1L1DKE Stitch 3.57E-03 1.00E+00 2.02E-02 2.29E-01 17 55 "ADORA1,ADORA2A,ADORA3,AK2,PLA2G6,P2RX6,AK5,LPAR6,AK8,GCK,LPAR4,P2RY13,P2RX7,P2RY1,NUDT11,NUDT10,P2RY12" Drug CID000006944 o-nitrotoluene Stitch 3.57E-03 1.00E+00 2.02E-02 2.29E-01 17 55 "AMH,DDO,NFS1,CBFA2T2,CACNA2D2,CNTFR,MRO,OLFM1,PDCD2,RBBP8,RDX,LRRC4,ABCC8,ZFP91,TNNT1,HPS4,ST8SIA2" Drug CID000061263 AC1L1UVI Stitch 3.57E-03 1.00E+00 2.02E-02 2.29E-01 17 55 "ANK2,ANK3,CLDN10,CASP8AP2,ERCC2,IRF8,BCO1,OLR1,PCDHGC3,RAD51D,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2,PLSCR4" Drug CID009862248 sobetirome Stitch 3.60E-03 1.00E+00 2.03E-02 2.31E-01 22 78 "HCN2,C5,CREM,NCOR1,MED12,SLC25A18,PPARGC1A,BRD8,GRK4,GUCY1A2,GUCY1B1,NPR2,NRGN,MED1,PPP5C,FUZ,SLC6A1,SLC14A1,TF,THRA,RASD2,TPM3" Drug CID000003696 imipramine Stitch 3.61E-03 1.00E+00 2.04E-02 2.32E-01 53 235 "SERPINA3,KCNH8,ACHE,BRAP,ADORA1,ADRA1D,ADRA1B,ADRB2,BCHE,NRP2,CALM1,CHRM1,PLCXD3,CALN1,DRD1,TUBD1,STX2,EFS,TUBB3,TUBB4A,ZMYND10,NEURL4,B4GALNT1,TUBA8,LOXL3,TUBA1C,PLCD4,GRIN2C,GRIN2D,CIT,HNMT,HTR2A,HTR5A,MYLK2,TUBB2B,KCNH1,KCNN3,MAOB,NELL1,PENK,PLCB2,PLCD1,RTKN,AP1AR,PLCB1,SYN1,SYN2,TRH,TUBB2A,TUBB1,TUBA1A,NUP214,NETO1" Drug 4690_DN Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ASIC1,SLC12A5,DOC2A,FAM131A,PPFIA3,RGS20,LDLRAD4,UBE2L6,SH2B1,BRINP1,SUGP2,ACSL4,TRAF3IP2,SEPT9,GFER,GLS,KPNA5,MBD1,MPP2,NF1,MED1,SAMD9,PTN,RAB3A,RAB3IL1,RGS10,RNASEL,FNDC3A,KIF13A,SOX2,MAPK8IP3,EXOC7,ZEB1,TRIM2,RPGRIP1L,PSD3,AHCYL2,SLC44A1,PARD3,FAM155A,VIPR2,DNALI1,KCNAB1,KAT6A,TIGD6" Drug 2142_DN Diflorasone Diacetate [33564-31-7]; Down 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "AP2A2,PLA2G6,RIPK1,SCAPER,CD86,ARHGAP33,FOXN3,RAB33A,ZFYVE9,PLAA,IQCK,FEZ1,DGKG,SGSM2,EGR3,RASGRP2,ST3GAL6,GAB1,USP19,HTATSF1,POLL,SLC2A6,LSS,MAP4,NRGN,ENPP2,GPR85,CDK14,MAPK3,PTPRO,TMEM231,RAB3IL1,ITSN1,SLC1A7,PREX2,FAM214B,SLC6A8,DOK5,NCDN,STX1A,EXOC7,TCF7,TRPS1,ZNF24,ST7" Drug 4225_DN Carcinine [56897-53-1]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "TRMT9B,APC,APOC1,CDK10,SEMA4G,CDK13,NCOA1,ADGRB2,ST3GAL5,SCARB1,B4GALT6,LHX2,NRG2,SIDT2,EGFR,SORBS3,MTSS1L,ST3GAL6,SCARA3,SEPT9,RUNDC3A,ZNF276,CRCP,LPAR4,GRM1,HSF2,PPARA,PRKAR1B,MAPK7,GRAMD1C,KCTD17,ITSN1,PPP4R3A,KANSL3,ZNF667,ZBTB43,CEP68,TEX15,TIAM1,CABIN1,AMACR,OSBP2,XRCC4,KCNAB1,NUP214" Drug 3857_UP PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "DPF1,BEGAIN,SEMA4G,CFLAR,MTMR3,USP2,CDH10,CLGN,TPP1,FADS2,CRMP1,NCOR2,SNPH,DAPK3,SMG7,DYRK1A,AASS,C3orf18,FGF13,CAMSAP1,C1orf61,AGAP2,CAMKK2,RND1,GLYR1,HTATSF1,GPD2,KCNH2,KCNJ5,KCNMA1,LSS,TM6SF1,MMP16,NF1,OMG,PCDH8,MAPK7,SLC1A3,ZCCHC24,HECW1,ZBTB43,ACSBG1,VAMP1,SMG6,ZBTB38" Drug 6997_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "NDRG2,SLC12A5,APP,DNAH17,NCOA1,KIF1A,CFLAR,SCAPER,CFAP410,B4GALT6,QKI,TCEAL2,SH2B1,MED12,DRD1,EDNRA,EDNRB,VPS26C,FER,KIAA1109,POLL,GPER1,CNTRL,MAPT,NUMA1,PCDH9,RETREG1,PRKAR1B,GTDC1,RGS3,PAQR6,SELL,SLC22A4,KDM4B,SOX2,JMJD6,TACC1,ANKRD12,WSCD1,TCF7L2,TPM1,VIPR2,PRDM2,KCNAB1,SSPN" Drug 3262_UP "Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "RBM10,DGKD,PDXK,MARK4,WASF1,CFAP410,CACNA1A,USP2,STOML1,WHRN,NCOR1,C2CD2L,ATN1,SEZ6L2,CNNM1,SIDT2,F3,PRRC2B,GPER1,CACFD1,GRM8,L1CAM,ZNF862,NRGN,NUMA1,PALM,MAPK7,KCTD17,SH3BP2,AMBRA1,DHX30,ARFGAP1,SMARCA4,WDTC1,TBCEL,SYNE1,OBSL1,KCTD2,WBP2,TRIO,VGF,WIPF1,KLC2,SPHK2,KAT6A" Drug 3221_DN Metergoline [17692-51-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ADORA1,AK2,BIN1,ARHGDIG,RGS20,ASPH,RIPK1,SOCS6,EPS15L1,ZFYVE9,VAX2,HOMER3,CSF1,PARD6A,EFNA3,IRAK4,LRRC23,STX2,VPS26C,SEPT9,GLS,GRM8,ATXN2L,HNMT,INPP5B,KCNQ3,LMO2,KITLG,ZNF862,OGG1,PCDH9,RGS12,EMID1,RASA3,ASAP3,NLGN1,PKNOX2,BTBD7,KDM4C,TROVE2,PLCB1,PCDHA5,VGF,REEP1,NUP214" Drug 6869_DN STOCK1N-28457; Down 200; 20uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "NDRG2,BIN1,CDC42BPA,APBA2,GAS7,ADAM15,CFLAR,BAIAP3,CA4,CLGN,CHRNB2,RAB33A,ST18,RASSF2,TBC1D5,DTNA,DUSP9,LRRC17,ANKMY1,KIAA1109,BAIAP2,DISC1,GLYR1,RAB30,ATXN2L,HSF2,TJAP1,KCNJ3,LIG4,LSS,MBNL1,MIA2,MSR1,NF1,NUMA1,RETREG1,PLEC,RAB3IL1,RGS12,ELMO2,CEP68,DNMBP,DMXL2,TCF7L2,RBFOX2" Drug 4834_UP Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "AP2A2,SYT13,SLC4A4,BCL2L2,CACNB2,PLAA,CLCN4,ARHGEF6,SLC4A7,CSF1R,NOS1AP,SPOCK2,ARMCX2,ACSL4,OLFM1,FOXG1,AFF2,HBS1L,RAB30,GNAO1,KLF12,HMGCR,ICA1,ITIH2,KCNJ5,KCNK1,MAN2A2,MAP2,BCO1,TAGLN3,SERPINE2,PURG,STRN3,MINDY2,SNRK,PTHLH,SLC25A36,SH3GL3,SLA,KANSL3,WDTC1,PEG10,AJAP1,PSD3,SLC30A3" Drug 6422_DN STOCK1N-35215; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "CDC7,AK2,FAM131A,MARK4,MPDZ,CDC42,SLIT2,LHX2,RAB28,CRMP1,PDE4DIP,C2CD2L,RBM12,DLC1,DPYSL4,SYT17,GART,GPR19,STON1,CNTRL,MAP4K5,KHK,MEIS2,NEK1,ZCWPW1,RET,KCTD17,CCDC25,EMID1,PAQR6,DHX30,DOP1A,FNBP1,GLT8D1,SPTAN1,ITPRID2,ST5,ARC,FAM208A,KIAA0930,UBTF,WRN,EMSY,MPPE1,ACTR3B" Drug 2721_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "KIDINS220,AMPD3,KCNAB2,KIF1A,MTMR2,C5,CACNA1A,EPS15L1,RAB28,ZFYVE9,NRG2,CTH,CTNND1,EDRF1,RUSC2,NR1D2,DTNA,E2F5,HIPK3,EIF1,MTSS1L,PDLIM5,CAMKK2,KHDRBS3,CSPG5,ZMYND11,GNG4,GRM7,IL6ST,SMAD1,MAP4,NDUFA5,NF1,NNAT,POLG,FAM120C,SH3BP2,PREX2,SLC11A1,TROVE2,ZNF34,KAT6B,TPM3,LMF1,PRDM2" Drug 6421_UP PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ABHD6,ADCY6,ADRA1D,MTUS1,ARRB2,SLC4A4,ST3GAL5,CDH2,KIAA1549L,HOMER3,CNTNAP2,ARHGEF4,SMG7,SGSM2,FEM1B,EFNA3,SUGP2,MRNIP,FGFR1,FOXG1,FYN,GLYR1,GLUL,STON1,GIT1,MSRA,PLCD1,SAMD9,NEK11,MCMBP,ATXN7,ITSN1,KIF16B,PEX26,FAM214B,SLC22A4,IFT122,BEX1,SYT1,IQCE,AHCYL2,TK2,WBP2,MAP3K12,MPPE1" Drug 3296_UP Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "AMPD3,PLA2G4C,ATM,SLC4A4,CFLAR,CFAP410,RUNX1T1,FOXN3,SLIT2,PPP6R2,CTIF,CDON,EDNRB,EGFR,TNK2,SPEG,CAMSAP1,GAD2,ALDH1L1,GNAL,GNG4,HLF,SMAD1,ADAM22,NPPA,CLDN11,PLTP,PRKACB,PTHLH,RAB3IL1,RGS4,RPS6KA2,CNKSR2,SLC1A2,SLC9A5,SOX10,CLSTN2,PCDHGA10,TEX15,HEY2,CABIN1,TRPC1,VIPR2,VLDLR,NT5M" Drug 6400_DN AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ADCY6,KIDINS220,PKP4,SCAPER,CACNA2D1,CLCN4,SH2B1,PHF14,CTNND2,ABCC9,EGFR,AASS,STX2,SEMA4D,FLT1,DENND2A,B4GALNT1,RUNDC3A,GNAS,GRM1,GRM8,KLF12,LAMA2,VWA5A,MATN3,KITLG,PDE1C,PGAM2,PTN,TMEM206,ZNF671,CSRNP3,SLC15A2,ZNF667,SCN3B,SOX10,TROVE2,NCDN,GPR161,TK2,TNS1,TRIO,ZMYND8,UBE3A,SLC17A7" Drug 901_DN 5114445; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ASPHD1,CDK10,B4GALT6,QKI,RUBCN,DNAJC6,DSCAM,EFEMP1,KAT8,POLR1B,FGFR3,PRKAG2,EFCAB2,ZNF276,CRCP,GPER1,AGFG1,HSF2,JAK2,KCNJ3,MAN2A2,MAP4,NF1,OXTR,PDPK1,RET,ROBO1,IL17RB,SEC14L1,SYBU,DHX30,ERC1,SPTAN1,CLASP2,JMJD6,PRRC2C,TACC1,MCF2L,EXOC7,TCF7,DICER1,ZKSCAN5,HIRA,PRDM2,EPM2A" Drug 5989_DN Trichlorfon [52-68-6]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "SLC12A5,AK2,APLP1,ASPH,ATM,EIF4G3,BCL7A,CFLAR,SYNJ2,ARHGEF2,HOMER3,FEZ1,PDE4DIP,CNTNAP2,DZIP3,CTNND2,DBT,EFNA3,SORBS3,MRNIP,DENND4A,EZH1,FGFR1,BAIAP2,INPP5K,TXNL4A,GLS,HNMT,KCNF1,KHK,MAP4,MINDY2,SAMD9,GON4L,RALGDS,ZNF430,ZBTB43,TROVE2,TCF7,TMEM121,TK2,CABIN1,HIRA,HPS4,MVB12B" Drug 5239_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ABHD6,PPFIA3,CDK13,ATP2A2,KIF1A,CRLF1,PPP6R2,MAML1,DBN1,C2CD2L,EGFR,EIF5,ENO2,FGFR1,FGFR3,BAIAP2,GCNT2,SRCAP,GFER,MALT1,GRB10,ATXN2L,IL6R,INPP1,KCNF1,VWA5A,MAPT,MBD1,PDE4A,MED1,MAPK7,GON4L,RIPOR1,SNCA,SOX2,POPDC3,KAZN,MTCL1,MCF2L,PSD3,TMEM121,AP4E1,TRIO,MICAL1,GDPD5" Drug 6423_DN C75; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "RALGAPA1,ALCAM,CDC42BPA,PKP4,APAF1,APLP1,CDK10,PPP4R4,CDC42,SLIT2,COL4A5,CRMP1,PDE4DIP,TBC1D5,DNAH9,NR1D2,EDNRA,LRRC23,STX2,EZH1,KAT8,TXNL4A,HTATSF1,POLL,NR3C1,ARHGAP19,ICA1,KCNF1,MMP17,MPP2,ADAM22,ODF2,PRKAR1B,KCTD17,TCP11L1,PPP1R9A,PEX26,LIMS2,UHRF1BP1L,CEP68,VAMP1,TRIM2,PSD3,TRIO,PLPPR2" Drug 3479_DN Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "NDRG2,ADRA1D,ALCAM,APBB2,APC,APP,ARHGEF7,CAMK2G,PLEKHB1,IQCK,SOCS5,EDRF1,DBN1,EDNRA,EIF4G2,MRNIP,ANKFY1,SYT17,GCNT2,GLYR1,LPAR4,CACFD1,NR3C1,LSS,MAPT,MIA2,NUCB1,SETD4,OXTR,PDPK1,RETREG2,DCUN1D2,NEK11,SHANK2,KDM4B,SOX3,FNBP1,CAMTA2,THSD1,PLCB1,CDK20,ZKSCAN5,VAV2,LMF1,AAAS" Drug 893_DN pararosaniline base; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ABHD6,ADD1,ADD3,ATP2A2,RAB29,CCNT1,LHX2,ENTPD4,AKAP12,MICAL2,SPATA2,DTNA,RBM12,EXTL2,ARMCX1,SCML2,FGFR3,GPER1,BTN2A1,FICD,INPP5B,JAK2,NAP1L2,NASP,NRGN,PIK3R1,PMP22,MBOAT7,LRRC49,RGS10,SBF1,ITSN1,EPN2,TROVE2,NCDN,ELOVL4,NSFL1C,TNS2,ZMAT3,KCTD2,HIRA,RPRM,GDPD5,MPPE1,EPM2A" Drug 1926_DN Glipizide [29094-61-9]; Down 200; 9uM; PC3; HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "KIDINS220,GAS7,ARHGAP5,STX16,MTMR2,WASF1,CDC27,CDH2,SLC4A7,CREM,RNF14,SOCS5,APPL1,ABI1,AMOTL2,SEC23B,ATP2C1,STAG2,GLS,MAP4K5,IL6ST,KTN1,NAP1L1,PTPA,PPP3CA,PKN2,APTX,ZSCAN32,C1orf109,GTDC1,PCMTD2,ZC3H14,WDR47,SMARCC2,CLUAP1,PEG10,TCF7L2,DICER1,TPD52,UBE3A,KLC2,ZNF189,UPF3A,EVI5,ST7" Drug 6331_DN Fenoterol hydrobromide [1944-12-3]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ACTN1,ADRB2,CDC42BPA,ASPH,MPDZ,KIAA1549L,CLCN4,NMT2,NIPBL,CHD1L,TENM4,GIT2,DYNC1I1,F3,ST3GAL6,FCGRT,FER,PDLIM5,FAM49B,TRAF3IP2,NCKAP1,GBX2,TXNL4A,PRRC2B,GPD2,MID1,PDE1C,PTN,PTX3,SH3TC2,RGS10,CCDC25,CLIP1,FAM102A,SMTN,PDZD2,ZBTB43,TACC1,RBFOX2,TRIO,RUNDC3B,TRPM2,HIRA,NAV3,ACTR3B" Drug 3209_DN Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "APP,CDC14B,ALDH4A1,SCARB1,QKI,HOMER3,WHRN,FEZ1,PDE4DIP,CTH,DAPK3,DBT,SLC12A6,EDNRA,FEM1B,BAIAP2,ERAP1,SEPT9,GART,TXNL4A,GLS,NR3C1,AGFG1,DHX35,JAK2,MBNL1,KITLG,PRKAB2,MAPK7,MAPK8,EPN2,ZCCHC24,KDM4C,IQSEC2,TROVE2,NXT2,ARHGEF9,EXOC7,PCDHA6,TMPO,CABIN1,RBFOX2,VGF,REEP1,MPPE1" Drug 3810_DN (1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ASPHD1,MRTFA,AMPD3,APC,EPB41L5,ZSCAN18,RASL11B,ATP1A3,NRP2,SCAPER,BTRC,CACNB2,AKAP7,RCHY1,SH2B1,CSF1,MICAL2,CTNND2,EXOG,DTNA,EDNRA,FGFR1,TRMO,OGA,FYB1,KCNMB4,GRIK5,ICA1,TJAP1,IL11RA,MAPT,MN1,NDP,NUMA1,OGG1,PTPRB,ZCWPW1,RASA3,SH3BP2,OGDHL,ARHGAP26,GPR161,TNS1,HIRA,EPM2A" Drug 979_DN ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "ABHD6,NDRG3,ADD3,ALAD,APP,ARRB1,NCOA1,MPDZ,CFLAR,RAB29,PLEKHB1,LHX2,DCAF8,PARD6A,DPH1,RBM12,RRAGB,FGFR3,TRAF3IP2,GLYR1,HTATSF1,CNTRL,BRINP3,KCNH2,KCNJ3,KHK,MPP2,ADAM22,PDE3B,PKIA,FAM192A,FERMT1,FUZ,ZKSCAN3,SMARCD3,ZBTB43,NXT2,ELOVL4,CEP68,AP4E1,BHLHB9,KAT6B,UBTF,ZNF24,PHTF2" Drug 6022_UP Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "CLK4,ANK1,SEMA7A,APBB2,CA4,HAP1,INA,ARHGEF1,NEURL1,SRSF11,FAM189A2,CYBB,BRINP1,GSDME,ST8SIA3,REEP2,TUBB4A,BAIAP2,ALDH1L1,SESN1,ATF7,GRK4,PCLO,TJAP1,ZNF862,PPM1B,MAPK10,PTH1R,C1orf54,TCP11L1,RPS20,RASA3,PPP4R3A,SMARCC2,PEG10,MAPK8IP3,VAMP1,SYT5,WSCD1,ZMAT3,TMOD1,PARD3,AMACR,FAM155A,VGF" Drug 2177_DN Benfotiamine [22457-89-2]; Down 200; 8.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "NDRG3,NDRG2,ADRA1D,APOC1,ARRB1,ASPH,N4BP2L1,ADAM15,BACH1,ZNF589,KIAA1109,FYB1,GALC,ARFIP1,GPR19,GPR22,ITGAM,KIF2A,LIG4,MYT1,SETD4,PDE4B,PLP1,RNASEL,TCP11L1,ZNF667,TMCC1,IZUMO4,SS18,MAPK8IP3,EXOC7,CAMSAP2,EHBP1,TCF4,TCF7,TCF7L2,ZEB1,NSD1,THRA,R3HDM1,PARD3,TPM1,TPM3,SSBP2,EPM2A" Drug 1988_UP Captopril [62571-86-2]; Up 200; 17.2uM; HL60; HG-U133A Broad Institute CMAP Up 3.62E-03 1.00E+00 2.04E-02 2.32E-01 45 193 "SPOP,SHROOM2,CDK10,MADD,SLC4A4,WASF1,CACNA1A,FOXN3,QKI,SLC4A7,PREPL,SPOCK2,DBN1,DPYSL2,CELF1,STAU2,RAB30,GPR12,MUM1,OPA1,PDE4A,RETREG1,PLCD1,FTO,PTPA,MAPK3,VPS13C,GON4L,RAB3A,RAP1GAP,ZNF821,FAM102A,KBTBD4,ARFGAP1,KDM4B,EMC1,SPTAN1,MAPK8IP3,SEPT8,STX1A,TACR1,TCF4,TMOD1,TSN,PRDM2" Drug CID000023931 mercury Stitch 3.64E-03 1.00E+00 2.05E-02 2.33E-01 109 543 "ABAT,TMCC3,AGT,ALAD,GAS7,AQP4,AQP6,ATP2A2,ATP2B1,ATP2B2,ATP2B3,AZGP1,BCHE,CDK5R1,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,KRIT1,MYOM2,LRRFIP1,CACNA2D2,SLC22A6,CLTC,ABCG2,MAP4K4,ABCG1,SEC24C,BOC,DCT,HEPH,DTNA,DTNB,ABCC5,EDN1,EDN3,EDNRA,EDNRB,CACNG7,TMEM35A,USPL1,TUBD1,F5,FABP7,CACNG2,TUBB4A,AGAP2,FOXO3,DPYSL4,ATP2C1,DNER,TUBA8,MSTN,OS9,LILRA2,NR3C1,TNFAIP8L3,HSP90AA1,IGF1,IL6ST,INPP1,TUBB2B,KCNH2,AQP11,MT3,MYH7,NAP1L1,NODAL,NPPA,PDE3A,CDK14,PIK3C2A,ANLN,PIK3CD,PIK3R1,PKD1,ANKHD1,PRIMA1,GSTCD,RYR1,RYR3,MAPK12,IL17RB,COPZ1,DOCK10,SLC11A1,SOX10,SPP1,ERC1,CLSTN2,ITPRID2,PLCB1,TAC1,LEFTY2,PIK3R5,PPIL6,TUBB2A,TUBB1,SLC13A3,FTSJ1,RGMA,NAV3,MVB12B" Drug CID000001181 UTP-NA Stitch 3.65E-03 1.00E+00 2.05E-02 2.34E-01 87 420 "ADAR,ADARB2,ADCY2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ADRA1D,NME5,PLA2G6,APC,UPRT,ATP2A2,ATP2B1,ATP2B2,ATP2B3,CALM1,CCNH,CCNT1,P2RX6,ENTPD2,LRBA,CPS1,ENTPD4,PLCXD3,EDN1,EDN3,LPAR6,ERCC2,PTK2B,POLR1B,NELFCD,CAMKK2,ATP2C1,GALR1,GCK,GLS,KCNMB4,LPAR4,PLCD4,GUCY1A2,GUCY1A1,GUCY1B1,GYG1,KCNMA1,KCNN1,KCNN3,PACRG,HNRNPM,P2RY13,NME4,NPPA,NPR2,P2RX7,P2RY1,ENPP2,PFKP,PKM,PLCB2,PLCD1,POLR2F,PPARA,PRKACB,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,SPP1,ARHGAP26,SUPT5H,PLCB1,SYT1,TAF6,TAF9,TCEA1,TK2,TRPC1,UBTF,VAV2,P2RY12,POLR3H,NELFE" Drug CID000181976 3-hydroxyglutaric acid Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "GAD1,GAD2,GCK,GRIN2C,GRIN2D,OGDH,SUGCT,SLC13A3" Drug CID000010104 NSC 234205 Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "AGT,ATP1A1,ATP1A2,ATP1A3,ATP1B3,CBFA2T2,MAPK3,TAC1" Drug CID000122149 AC1L3U2Y Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "EDN1,EDN3,EDNRA,EDNRB,GCK,NEUROD1,NPY,PTHLH" Drug CID000092891 albizziin Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "KYAT1,GGT7,GGT5,GLS,GLUL,GPT2,NBL1,ASRGL1" Drug CID000013314 lormetazepam Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "AASS,ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000060790 OPC-18790 Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "ALDH7A1,CALM1,KRIT1,KCNA4,KCNB1,PDE2A,PDE3A,PDE3B" Drug CID000002628 K1-70 Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "SLC22A6,KCNK3,P2RY1,TMEM132D,MCF2L,RASD2,TPM3,SLC13A3" Drug CID000013820 triethyltin chloride Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "ABAT,ALDH7A1,KRIT1,DYRK1A,GFAP,MBP,PDE4B,SYN2" Drug CID000395493 alpha-quarterthiophene Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "CACNA1A,CHM,CASP8AP2,SEMA4D,GRM1,BCO1,TRIO,TSC2" Drug CID000037497 etidocaine Stitch 3.67E-03 1.00E+00 2.06E-02 2.35E-01 8 18 "OGA,ATP8A2,KCNK1,KCNK2,KCNK3,CLDN11,PLIN1,UBTF" Drug CID000007371 benzenesulfonate Stitch 3.69E-03 1.00E+00 2.07E-02 2.35E-01 14 42 "ANK1,DBT,FDFT1,GRIK2,HMGB1,LIFR,MARK1,PRKCB,PRKCG,PKN2,PRKCZ,RAB3IL1,FTSJ1,RNF103" Drug CID000068424 isobutyramide Stitch 3.69E-03 1.00E+00 2.07E-02 2.35E-01 14 42 "CA4,NGB,PRC1,CNR1,HEPH,GRIK1,GRM1,GRM2,GRM5,GRM8,HBA1,MAP4,ADHFE1,JMJD6" Drug CID000004798 AMPCP Stitch 3.69E-03 1.00E+00 2.07E-02 2.35E-01 14 42 "ADAR,ADARB2,BRAP,ADORA1,ADORA2A,ADORA3,APC,NT5C3B,ALDH7A1,ATP6V0A1,SLC29A4,SEMA4D,P2RX7,P2RY1" Drug CID005278688 N-N-C Stitch 3.69E-03 1.00E+00 2.07E-02 2.35E-01 14 42 "DRD1,ABCC9,MCHR1,HRH3,OPRL1,PDCD2,PTCH1,SLC6A1,SLC6A11,SST,SSTR1,SSTR2,ABCC8,TNR" Drug CID005311081 endomorphin 2 Stitch 3.69E-03 1.00E+00 2.07E-02 2.35E-01 14 42 "RGS20,CCK,DMTN,B3GAT1,IL12A,OPA1,OPRL1,PDYN,PENK,PRKCG,JMJD6,TAC1,TACR1,TRPC3" Drug 2239_UP Nocodazole [31430-18-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "MRTFA,ATP2B1,BMP7,CACNG1,RAB33A,STOML1,ARMC8,SLC4A7,FEZ1,SIPA1L1,VCAN,PDE4DIP,DTNA,EDN1,SH3GLB1,EGR3,CDKL3,FGFR1,PRELID3A,GAD1,ATP8A2,RUNDC3A,GNG3,KCNMA1,ZNF862,NF1,SMOX,SMIM7,PACSIN1,PTPRE,SEMA6D,ATXN1,SH3BP2,BCAN,ZNF365,ZNF423,SPART,FAM208A,CRTC1,PARD3,VAV1,XRCC4,NAV2,PLSCR4" Drug 974_UP ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "LTBP4,EP400,CDC14B,MARK4,BCL7A,ST3GAL5,BTRC,HIP1R,CCNT1,DCAF4,GPRASP1,SGSM2,DMPK,TRAPPC9,DTNA,TOM1,SCML2,POLR1B,FHL1,IQCG,PDLIM5,FAM49B,GPR153,CSPG5,OGA,RND1,HMGCR,KIF5C,SIDT1,RAB3IL1,RPS6KA2,PAQR6,SBF1,FBXO11,SMTN,SLC6A8,BTBD7,EXOC7,TBL1X,TRIM2,RBFOX2,PMEPA1,GDPD5,ST7" Drug 6885_UP AH23848 hemicalcium salt hydrate; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "BRAP,AK2,ARNTL,ATM,STX16,CFLAR,SULT4A1,ENTPD4,DBT,SMG7,FCF1,APH1A,IRAK4,TUBD1,FOXG1,AGAP2,FAM49B,ZNF44,KCNMB4,IL12A,MDFI,EPN1,PMS2,MINDY2,CNNM2,SAMD9,SYTL2,RAB3IL1,PLEKHB2,GAL3ST4,SELL,ZNF821,SUPT20H,ASAP3,NUBPL,ZNF430,SLC20A2,COA1,POGZ,SS18,TCF4,TRIO,HIRA,EMSY" Drug 3480_DN Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "CAMK2G,EPS15L1,QKI,AKAP12,FAM169A,GREB1,EDRF1,MFAP3L,RHOBTB1,RASGRP1,EGR3,EIF4G2,SEMA4D,FAM49B,GLYR1,POLL,GNG4,LPAR4,HNMT,IL6ST,JAK2,MAP4,MITF,MMP16,NRGN,PDE4A,RETREG1,MBOAT7,ZSCAN32,RAD51D,RET,RGS10,IL17RB,SGK1,RBM34,SOX3,EMC1,CDK19,SPART,NCDN,DIP2A,TIAM1,CDK20,KCNK12" Drug 7104_UP "Forskolin, from Coleus forskohlii; Up 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "ASPHD1,GRAMD1B,NME5,ANK3,MARK4,ASPH,ATP2B1,CFLAR,MAP7,WHRN,CREM,AKAP12,CSNK1E,CTH,ARHGEF4,DBT,PITPNC1,C2CD2L,ARNT2,ATN1,EDIL3,FEM1B,EFNA3,CELSR3,TACC2,GAD1,ARFIP1,KCNMB4,GPER1,SHISAL1,MMP17,PDE4B,NLE1,PTHLH,RGS10,FBXW7,ATXN7,FAM214B,CCDC88A,SS18,COBL,ROBO3,TCF4,RPGRIP1L" Drug 5239_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "APBB2,APC,ASPH,ST3GAL5,SYNJ2,RUNX1T1,CLGN,CHM,ABCG1,CTH,TBC1D5,RIMS3,SPOCK2,SMG7,NTM,CDON,SLC12A6,FCF1,MBNL2,ING4,DMTN,EZH1,SRCAP,POLL,GPER1,GRIK5,NR3C1,SMAD1,MX1,ZNF862,NF1,PLCD1,RETREG2,RAD52,CARF,SH3GL3,CDK19,PCDHA5,ZMYND8,UCHL1,VIPR2,MARCH8,TIGD6,SSPN" Drug 7370_UP Mebendazole [31431-39-7]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.70E-03 1.00E+00 2.08E-02 2.36E-01 44 188 "CLK4,GRAMD1B,PLA2G6,CFLAR,CAMK2B,CBFA2T2,REPS2,DNAJB5,ARMC8,WHRN,SLC4A7,AKAP12,CTH,RIMS3,CNIH3,CHRDL1,TENM1,C3orf18,ZNF391,ANKMY1,ZNF589,PDLIM5,DENND2A,ALDH1L1,USP19,MMP16,TAGLN3,CNOT4,CLDN11,PDE4D,PRKAB2,PRKAR1B,RGS4,ROM1,IL17RB,CCDC92,NLGN1,SLC4A3,THSD1,SYT1,KAZN,GPR161,TRIO,NUP214" Drug 5613_DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.78E-03 1.00E+00 2.12E-02 2.41E-01 43 183 "ADD3,APBB2,PPFIA3,PDE8B,SCAPER,BTRC,CA12,KRIT1,NECTIN3,CTNND2,RBM12,EGR3,VPS13B,GPHN,FER,NBEA,GHR,PSRC1,BRINP3,INPP5B,JAK2,MAP4,MEIS1,MMP16,NRCAM,PIK3R1,PPP3CC,PKIA,PTPN13,LGR4,FOXRED2,SHANK2,TMCC1,SON,CLASP2,SYT1,TCF7L2,WDR7,DOCK9,PARD3,KAT6B,TRPS1,SSBP2" Drug 5275_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.78E-03 1.00E+00 2.12E-02 2.41E-01 43 183 "ALCAM,CAPRIN2,CFLAR,LRRFIP1,LHX2,GIT2,ZBTB24,RHOBTB1,SACS,ANKRD46,EFNA3,RBM12,ARMCX1,GPR19,ITPKB,JAK2,MEIS1,PDCD2,PIK3R1,PRODH,ZSCAN32,RAD51D,RNASEL,ROBO1,SUPT20H,ITSN1,PAAF1,SPATA7,CLUAP1,RAP1GAP2,CEP68,KANK1,ZC3H4,ARHGEF9,FAM208A,TRIM2,METTL3,ZMYND8,ZIC1,ZNF23,MPPE1,MVB12B,ZNF248" Drug CID003386230 AC1MPJID Stitch 3.78E-03 1.00E+00 2.12E-02 2.41E-01 30 117 "ADCY2,ADCY5,ADCY6,ADCY8,APC,ATM,BOC,DAPK3,ELAVL3,APC2,GAA,TRAF3IP2,GAD1,GAD2,HP,HPR,ICA1,LMO1,LMO2,MARK1,MMP16,MMP17,CTNNA3,NRGN,PSAT1,PTPRN,CLIP1,FNDC3A,SNRPN,UGT8" Drug CID005356750 Evans blue dye Stitch 3.81E-03 1.00E+00 2.14E-02 2.43E-01 32 127 "ADORA2A,ALAD,AMH,AQP4,SGCE,P2RX6,CRHBP,DMD,EDN1,B3GAT1,GFAP,GNAS,LPAR4,GRIA1,HRH3,ITGAM,P2RY13,NOS1,NPPA,P2RX7,P2RY1,PDE2A,PTPRN2,S100B,SCNN1D,TAC1,TAC3,TACR1,TMPO,NTSR2,P2RY12,SLC17A6" Drug CID000002514 cadmium Stitch 3.84E-03 1.00E+00 2.16E-02 2.45E-01 91 443 "ABAT,ASIC1,ACHE,ADAR,GPAM,APP,ARHGDIA,ARHGDIG,ATP2B1,ATP2B2,CACNA1I,C5,CACNA1A,CACNA1B,CACNA1D,CACNA2D1,CACNB2,CACNG1,CAMK2D,SLC5A11,RGN,AIFM1,CACNA2D2,CHRM1,FADS2,ABCG2,EARS2,DAPK3,CDON,DTNB,CACNG7,EGFR,CACNG3,CACNG2,PTK2B,ACTL6B,FGFR1,AGAP2,B3GAT1,ATP8A2,MSTN,TXNL4A,OS9,GPT2,GRM1,GRM2,GRM5,GRM8,TNFAIP8L3,HMGCR,HNMT,HSP90AA1,ITGAM,ITIH2,KCND1,KCNMA1,MAT2A,MSRA,MT3,NCAM1,NODAL,SLC11A2,NUCB2,OGG1,CNTN3,SERPINE2,ANLN,PKD1,PRKCB,PRKCG,MAPK9,RNASE1,GSTCD,RPL15,RYR1,RYR3,COPZ1,SLC1A3,SLC11A1,SOX10,PEG10,PLCB1,TPCN2,DICER1,ACTR6,SLC35A4,PDIA2,SLC30A3,SLC30A4,PRTFDC1,PLD4" Drug 4716_UP 0175029-0000 [211245-78-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.85E-03 1.00E+00 2.16E-02 2.46E-01 42 178 "NME5,ATP1A3,FUBP1,QKI,SOCS5,EDRF1,ZNF337,MAML1,SPOCK2,HIPK3,FCF1,RASGRP2,KIAA1109,IP6K2,ATP2C1,SESN1,GLYR1,GRIK5,NR3C1,KCNH2,KITLG,NFYA,CNOT4,SMIM7,STRN3,PPP5C,PRKAB2,FAM120C,FBXW7,SFPQ,CPEB3,PPP4R3A,SNCA,ZBTB43,DDN,SAMSN1,PLCB1,ZMAT3,TRPM2,ZNF24,PRDM2,RNF146" Drug CID000003224 endosulfan Stitch 3.92E-03 1.00E+00 2.18E-02 2.48E-01 24 88 "ACHE,MIER1,CBS,GSDME,IGSF6,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GPT2,CIT,PTPN5,HP,HPR,ABCB1,PTPRN2,GSTCD,SAFB,TIE1" Drug 5105_UP Parthenolide [20554-84-1]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 41 173 "KIDINS220,BACH1,SYNJ1,CBFA2T2,CLU,DNAJB5,WHRN,CREM,MICAL2,CTIF,EDN1,CELSR3,CDKL3,F3,BAIAP2,IP6K2,SORBS1,RND1,GLS,ZNF862,NHLH1,SETD4,PFKFB3,SERPINI1,SMIM7,MAPK7,PTHLH,C1orf54,PAQR6,KDM4B,ZBTB43,TSPYL2,JMJD6,ARC,ZNF34,TRPC1,TRPC3,PRDM2,RNF103,NAV3,CAMK1G" Drug 2007_UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 41 173 "ADD3,GAS7,ARNTL,DNAH17,SLC25A14,CD86,CD38,ARHGAP33,FOXN3,CHN2,CREM,SIPA1L1,PPP1R16B,DOCK4,FAM13A,ING4,KIAA1109,FAM49B,GALC,MEF2C,PDE3B,PDE4B,PDE4D,GPSM2,SMOX,PTPRE,PTX3,RPS6KA2,SATB1,FAM214B,ARHGEF40,DOP1A,ZSWIM8,SPTAN1,CDK19,SAMSN1,EPB41L3,STXBP1,PLCB1,EXOC7,FLRT2" Drug 1841_UP Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABAT,ACTN2,AP2A2,AMT,CDK10,SEMA4G,CAPRIN2,NCOA1,NUMB,ALDH4A1,N4BP2L1,ADAM23,CSNK1E,GIT2,SMG7,DLG4,DYRK1A,SIDT2,EFNB3,NCALD,SRCAP,GRIK5,HMGB1,KCNN3,SMAD1,GIT1,MYT1,NF1,NPR2,C11orf49,MINDY2,CNNM2,ACSS3,RAP1GAP,ARHGEF10L,PREX2,PKNOX2,BTBD7,SMARCD3,ARHGAP26,TSPYL2,ARHGEF9,SYP,KAT6B,UBC,XRCC4" Drug 1440_DN Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; HL60; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "APP,ATP2B1,BCL2L2,HIP1R,TJP2,LETMD1,CSNK1G3,CTH,GIT2,ZEB2,VPS13B,EPB41L2,STX2,DENND4A,VPS26C,EZH1,ACSL4,OGA,TRAF3IP2,DBF4,SPIN1,IPO5,PAXBP1,MKLN1,NFE2L2,SLC11A2,PIK3R1,PLCD1,PSMD13,BSDC1,CCDC88A,SLC12A2,ZCCHC24,SP2,FCHO1,NSFL1C,FAM168A,PRRC2C,VPS13A,TAC3,MCF2L,TCF7L2,R3HDM1,EVI5,PDSS2,ST7" Drug 1960_DN Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADD1,BRAP,PDXK,MARK4,ASPH,PTBP2,NIPBL,SOCS5,ZFYVE16,SPOCK2,DNAJC6,DYNC1I1,RCAN1,MBNL2,SORBS3,TACC2,UFM1,CAMKK2,OGA,ERAP1,GRB10,GRIK5,BTN2A1,GUCY1B1,MAN2A2,GIT1,SETD4,PPP5C,CNNM2,VPS13C,RBBP6,SUPT20H,SMTN,ELMO2,SMARCA4,LIMCH1,FNBP1,MAPK8IP3,VAMP1,ANKRD12,TCF7,TCF7L2,TRIM2,TCF12,KLC2,ZNF189" Drug 1325_UP Lysergol [602-85-7]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABAT,ASIC1,KCNAB2,ASPH,KIF1A,ADAM23,SYNJ2,MYRF,TAOK2,MICAL2,RABGAP1L,DLG4,MRNIP,RASGRP2,NCALD,SEPT9,INPP5K,MSL3,HTATSF1,LILRA2,GPR19,ATXN2L,N6AMT1,ZNF862,NUCB1,SMOX,TMEM231,GALNT10,ITSN1,FUZ,PPP4R3A,SNCA,KDM4B,WDTC1,DOK5,ATP11A,KAZN,DNMBP,TBCEL,PSD3,THBS4,TNS1,BEST1,MKRN3,REEP1,GDPD5" Drug 3430_UP Tinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ARID1A,PLA2G6,MARK4,SLC4A4,ALDH7A1,BTRC,CLGN,SOCS6,AKAP7,GREB1,DAPK3,DTNB,HSD17B14,GALC,GCNT2,GLYR1,GNG3,GPD2,CNTRL,GRM1,KCNJ3,MAP4,KITLG,ADAM22,CNOT4,NTRK2,PDE3B,MINDY2,RELN,RAB3IL1,EMID1,TRA2B,ITSN1,PREX2,COA1,SEPT8,AJAP1,PLCB1,EXOC7,IQCE,WSCD1,VAV2,LAT2,ZIC3,MAP3K12,SSPN" Drug 6731_DN Rolitetracycline [751-97-3]; Down 200; 7.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "APBB2,APOC1,ARHGDIG,KIF1A,ADAM23,BTRC,CAMK2B,CBFA2T2,AKAP7,CREM,BRINP1,EFNA3,RGS17,LRRC23,MTSS1L,CDKL3,KIAA1109,SEMA4D,FYB1,LYVE1,MSL3,GPM6B,TDRKH,SCIN,KCNN1,KIF5C,MBD1,SCAMP5,MN1,NEUROD1,PLXNB1,RAB3IL1,NUDT11,NEK11,FOXRED2,MAPK12,DOCK10,SMARCD3,TNS2,THRA,AMACR,SSBP2,OSBP2,NT5M,SCG2,PCBP4" Drug 1415_UP Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NDRG2,C1QTNF1,APOC1,ARRB2,CA12,TAOK2,SLC24A2,NCOR2,CSF1,PPP1R16B,SEC14L5,ZNF337,INTS1,HP1BP3,DLG3,TRAPPC9,ZNF589,CAMSAP1,FHL1,AFF2,DISC1,WASF3,GJB1,PRDM5,PTPRT,LIG4,MYO7A,NPY,SETD4,CAMKV,RETREG1,TCP11L1,PLPPR3,ZNF821,FAM102A,MAPKBP1,ZC3H13,LMO3,ZC4H2,MLC1,VAMP1,PARD3,TPM3,SSBP2,VGF,TFIP11" Drug 5844_UP Folic acid [59-30-3]; Up 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASIC1,MTUS1,AMT,ARNTL,SLC4A4,CFLAR,HAP1,CRLF1,ASIC3,CNOT8,AKAP7,PDE4DIP,DCAF8,GIT2,KIAA0753,EGFR,RRAGB,SCML2,FGFR1,CAP2,OGA,FYN,ERAP1,GLRB,BACH2,MATN3,MMP16,NUCB1,PENK,LRP12,PMS2,ZNF821,SLC14A1,IFT122,TMCC1,TSNAXIP1,KDM4C,ZBTB43,SYT11,PLCB1,ASTN2,TRPM2,FAM155A,UBTF,WIPF2,AAAS" Drug 404_DN wortmannin; Down 200; 0.01uM; ssMCF7; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "APC,CDK10,ASCL1,BRINP2,ATP2B1,CHN1,TJP2,AATK,CSNK1E,PDE4DIP,E2F5,SIDT2,OPTN,SUGP2,COQ7,SEC23B,SEMA4D,DPYSL4,CAMKK2,NCKAP1,COPS8,GLS,RNFT2,ARHGAP19,KHK,MBD1,MMP17,ADAM22,MX1,NF1,OGG1,C1orf109,CEP97,TCP11L1,FOXRED2,CHD9,ANKRD6,PPP4R3A,KBTBD4,SLC15A2,EMC1,ZC4H2,ZNF34,TRPC1,WIPF1,GDPD5" Drug 5870_UP Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ACTN2,PPFIA2,ARRB2,ALDH4A1,BMP7,CACNA1I,CDC42,ASIC3,B4GALT6,CLCN4,QKI,AKAP5,NCOR1,PDE4DIP,SPOCK2,ZNF589,GFER,C1QL1,TDRKH,LILRA2,GPR37,KCND3,PDE2A,PLP1,CEP41,CNTLN,PTPRE,ROM1,NEK11,ELMO2,WDTC1,DOK5,ZHX3,SPTAN1,SAMSN1,SSTR2,CEP68,KIAA1107,TF,SLC44A1,TRO,HIRA,RPRM,LMF1,XRCC4,MPPE1" Drug 2713_DN Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AMT,PPP4R4,CASK,ATP2A2,ARHGEF1,SOCS6,FADS2,AKAP7,NRG2,PDE4DIP,ZNF337,SV2A,TRAPPC9,TUBD1,NCALD,CDKL3,PCYOX1,KHDRBS3,ZNF276,MAN1B1,LSS,MAP4,NNAT,PENK,PIK3R1,CCSER2,POU6F1,PRKCZ,C1orf109,PEX5,RAB3A,ATG16L1,SLC20A2,KDM4B,DOP1A,WDTC1,SIN3B,SZT2,OBSL1,TK2,LMF1,CLIP2,REEP1,EVI5,HPS4,TIGD6" Drug 4480_DN Dacarbazine [4342-03-4]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "MRTFA,APC,ALDH4A1,SLC4A4,SCAPER,IL33,BTRC,CDC42,LY86,PICK1,VCAN,PDE4DIP,EDIL3,FEM1B,EGFR,SORBS3,ING4,SEPT9,STON1,KCNJ5,KIF5C,MPP2,NDUFA5,NFIX,PID1,GAL3ST4,SEC14L1,PPP4R3A,SLC9A5,BTBD7,CDK5RAP2,SNCA,UNC5B,ARHGAP26,NCDN,MAPK8IP3,COBL,TBCEL,FBXW11,TEX15,GPR161,CABIN1,RPRM,SYNC,PARP6,TIGD6" Drug 3200_UP Ketotifen fumarate [34580-14-8]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADCY2,NME5,KIAA1324,SYT13,APC,CDK13,BTK,CD38,NEURL1,B4GALT6,SLC24A2,TPP1,AATK,CSF1,RIMS2,HEPH,TMCC2,STX2,F8,ZNF589,FGF12,IQCG,GPR153,TPPP3,TDRKH,GRIN1,GUCY1A2,INPP5B,KCNA1,KHK,MEF2C,MYCN,CDK18,PPP5C,PRPH,PPP1R9A,SLC6A8,DOK5,MAPK8IP3,PHLDB1,PLCB1,SZT2,AMOT,WIPF1,ZIC3,NUP214" Drug 3430_DN Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADRA1D,EPB41L5,NUMB,EIF4G3,BCL2L2,CFLAR,GYG2,OSGIN2,PLEKHB1,QKI,HOMER3,GPRASP1,C2CD2L,RRAGB,ANKFY1,NCKAP1,SYT17,GLS,DIDO1,SLC2A6,DHX35,MAPT,ZNF862,NF1,NPR2,NRGN,PDE4A,PLEC,SLC25A23,RETREG2,MBOAT7,CNNM2,LRRC49,CEP97,MAPK12,PPP4R3A,EPN2,SIRT2,SLC20A2,KDM4B,CEP68,TACC1,TCF7L2,DOCK9,SLC44A1,NR2C2" Drug 1_UP "1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A" Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABHD6,OGT,APC,CAPRIN2,SLC4A4,ATP2B1,CADM3,CAMK2A,CBFA2T2,CRMP1,CLIP3,CSF1R,VCAN,BRINP1,C2CD2L,DPP6,GNE,VPS26C,ZNF589,FLNC,ZNF44,GAD2,GNG4,PRUNE2,FAM107A,LMO1,MGAT3,PLCD1,GON4L,PEX5,RIPOR1,FAM184A,RLBP1,TMEM206,ITSN1,ASAP3,AMBRA1,FBXO11,SLC15A2,KDM4B,UNC5B,PHF24,TMEM151B,OBSL1,CDK20,MPPE1" Drug 5279_UP Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASIC1,ACTN2,ADORA1,AMPD3,APC,GAS7,CDC14B,CDK13,ADAM23,MPDZ,SCAPER,CACNG1,CAMK2B,CDC42,CBARP,CLCN4,SULT4A1,CSF1,SDC3,RIMS2,DCAF4,MFAP3L,HS3ST2,TRAPPC9,EDN3,FRY,MTSS1L,FOXG1,FYB1,PRUNE2,GUCY1A1,SMAD1,PGAM2,STRN3,PILRA,KHDRBS2,KCTD17,NTNG1,FAM214B,KDM4B,SYT5,DMXL2,TRIO,KCNK12,NT5M,KCNAB1" Drug 143_UP tamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "RBM10,ADD3,ANK3,APAF1,CFLAR,BMP7,MTMR2,HAP1,DLGAP1,CHRNB2,TAOK2,TJP2,IQCK,CREM,NCAN,JAKMIP2,DTNA,TOM1,SUGP2,SORBS3,VPS13B,F5,C1orf61,FAM49B,SARAF,GFER,FERMT2,GPM6B,GRIK5,NR3C1,KCNJ9,MBD1,NEUROD2,NOS1,PC,PRKAR1B,RGS12,RLBP1,KCNIP1,EMC1,SYNE2,PLCB1,TAC3,ATMIN,TP53BP1,WNK1" Drug 3358_UP Furazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ARID1A,ADCY2,KIDINS220,NME5,C1QTNF3,PPFIA3,CHRD,KSR1,SYNJ2,ARHGEF1,RAB28,NCOR2,CSF1R,RUSC2,ETV1,KIAA1109,SORBS1,KHDRBS3,GCNT2,RUNDC3A,GPR75,MSL3,GNAO1,GRB10,IL6R,MAP2,AFF1,MOBP,MYT1,NPR2,PIK3CD,POU6F1,SAMD9,CCDC40,ZMAT4,RGS12,MYH14,ASAP3,SLC1A7,COA1,WDTC1,SYT5,TPM2,ETNPPL,ITM2C,MVB12B" Drug 1582_UP Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ACTN1,ARID1A,NDRG2,ADD3,BRAP,LRRFIP1,SH2B1,PPP1R16B,C2CD2L,EXOG,DTNB,SGK2,ENO2,TRMO,ATP2C1,GNAS,GNG3,PRRC2B,LILRB4,DIDO1,CACFD1,ICA1,IDH3B,ITGAM,NEFH,CDK14,PLCB2,PLCD1,CNNM2,SAMD9,TMEM104,PTAFR,PLPPR3,SAFB,SBF1,SH3BP2,EPN2,ELMO2,ARHGAP26,SPTB,NSFL1C,DMXL2,CBX5,UBTF,LMAN2L,ST7" Drug 5286_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NME5,ASPH,ATM,STX16,BCL2L2,CFLAR,BMP7,BTRC,ARHGAP33,RCBTB2,CHRNB2,LHX2,QKI,PDE4DIP,MFAP3L,SUGP2,IRAK4,F3,FGFR1,B4GALNT1,POLL,BTN2A1,KCNN1,KHK,SLC25A23,PPP3CC,PRPH,PTCH1,PTPN13,SEC61A2,RPRD1A,WLS,SLC20A2,SPTAN1,POGZ,THSD1,CEP68,JMJD6,VAMP1,TACC1,TCF7,ARHGEF12,KAT6B,TPM1,PLPPR2,MPPE1" Drug 5697_UP Chlormezanone [80-77-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NDRG2,ADORA1,AP2A2,ADGRF5,BIN1,OGT,CDC14B,AZGP1,SCAPER,DNAJB5,CABP1,NECTIN3,AATK,ARHGEF4,USH1C,EGFR,TENM1,ETV1,RASL10A,GABRA2,SRCAP,GLS,LPAR4,GRK4,GUCY1A1,SHISAL1,TJAP1,MOBP,MT1M,MYCN,NF1,PCDHGC3,CDK14,RAB3IL1,RFX2,SCN3A,ST8SIA1,PKNOX2,FAIM2,PHLDB1,TAC3,TCF4,TPM2,VLDLR,WIPF1,HRASLS" Drug 4550_UP Methimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "MTUS1,GAS7,SLC4A4,ALDH7A1,ST3GAL5,CACNA2D1,CAMK2B,CBS,SCARB1,CLCN4,NRG2,CPS1,ENTPD4,SRGAP3,ZNF589,FLT1,CSPG5,GAB1,ERAP1,GNG4,GPER1,ITGA7,JAK2,KCNJ5,KIF5C,NF1,NPTX1,P2RY1,PRKAR1B,PRPH,CNNM2,PTPRN2,ROM1,ASAP3,AMBRA1,FBXO11,SLC11A1,TNIK,ZHX3,RBM26,NPAS3,ADGRL3,KIAA1107,R3HDM1,TPM2,NT5M" Drug 3794_UP Oxaprozin [21256-18-8]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "DPF1,TTYH1,SYN3,APAF1,GAS7,INA,ADGRG1,FOXN3,VAX2,SULT4A1,AKAP6,SMG7,EDNRA,AASS,VPS13B,CACNG3,SEMA6C,GABRB3,ADAM28,RAB30,GPM6B,GRIN1,GRM2,GRM8,HPSE2,KCNJ5,MX1,MYL3,NPY,NTRK2,PPP2R2B,LRRN3,CNTLN,RGS12,RNASEL,HKDC1,CNKSR2,SLN,SEMA4A,DOCK9,TMPRSS5,HIRA,TUBB1,LAT2,SPHK2,FAM13C" Drug 4537_DN Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASPHD1,C1QTNF1,APC,MARK4,KIF1A,CBFA2T2,PLEKHB1,ABCG1,TENM4,ARHGEF4,PLPPR4,TOM1,FEM1B,SORBS3,TENM1,ETV1,MSL3,GRK4,HAS2,KLF12,SCIN,INPP5B,NDP,CNOT4,KCTD15,SAMD9,PTHLH,FAM184A,ZNF821,ZFP30,ST6GAL1,DZIP1,CCDC88A,SLC14A1,THSD1,SYT11,PLCB1,ASTN2,EXOC7,DOCK9,TNS1,ZKSCAN5,CADM1,TRIM9,NDRG4,MAP3K12" Drug 7418_UP Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASPHD1,ASIC1,ADCY6,PPFIA3,CFLAR,CDK5R1,MTMR2,BTRC,CA12,ARHGEF2,SOCS6,ENTPD4,MICAL2,HDAC4,DCT,C2CD2L,SMG7,HIPK3,EGR3,EIF4G2,HSD17B14,CDKL3,SEPT9,MSL3,RNFT2,RASSF8,KCNF1,KCNMA1,KHK,MAP4,MIA2,ZNF862,NF1,SETD4,PRPH,PTN,ZSCAN32,RIPOR1,WLS,SLC2A5,KAZN,CHST8,RBFOX2,TRPC1,TRPM2,ZBTB14" Drug 5634_DN Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABHD6,NME5,PDE8B,MTMR2,CHM,STOML1,PDE4DIP,DOCK4,DRD1,RBM12,RRAGB,F8,FGFR1,IQCG,DISC1,ALDH1L1,SRCAP,GLYR1,GLS,GNG3,CACFD1,RASSF8,KITLG,NDUFA5,NEK1,EPN1,PPP5C,MAPK7,RPS6KA2,SBF1,SH3BP2,FNDC3A,FAM214B,BTBD7,ZKSCAN3,COA1,SPART,TROVE2,PLCB1,KIAA0930,FAM155A,ZFP37,ZNF711,ZNF32,EMSY,URM1" Drug 5839_UP Kaempferol [520-18-3]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASIC1,ACTN1,ARID1A,BIN1,AMT,PKP4,ARNTL,ALDH7A1,CADM3,KIF1A,ST3GAL5,ARHGAP33,ASIC3,QKI,VCAN,PDE4DIP,MFAP3L,HS3ST2,SGK2,FCF1,SCML2,GALC,ERAP1,GPD2,GPM6B,GRK4,SPACA9,JAK2,ADAM22,TAGLN3,MYL3,STRN3,RAB3IL1,FAM184A,RGS10,MYH14,CSRNP3,ASAP3,FNDC3A,SHANK2,NMNAT2,SS18,MCF2L,TRIM2,ZKSCAN5,TFIP11" Drug 6300_DN Dextromethorphan hydrobromide monohydrate [6700-34-1]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "BIN1,CDC42BPA,ZBTB10,KYAT1,CCNT1,AP4M1,HAPLN1,ARHGEF4,KIAA0753,SPOCK3,OPTN,RGS17,DENND4A,F3,F8,TRMO,CINP,FYN,DISC1,GART,CRCP,JAK2,KCNMA1,L1CAM,MAP4,MEIS1,MN1,NOVA1,SLC11A2,OGDH,SLC25A23,PRPH,PTPN13,SH3TC2,GAL3ST4,SBF1,UNC5B,BEX1,ZBTB43,SS18,GSE1,IQCE,TRIM2,CLDND1,XRCC4,UPF3A" Drug 6641_UP Khellin [82-02-0]; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADCY6,LTBP4,MRTFA,SEMA7A,ADAM15,CAST,KRIT1,CLCN4,WHRN,ENTPD4,DBN1,CHRDL1,MBNL2,ELAVL3,REEP2,FCGRT,ZNF589,FGR,FLT1,ZNF276,ATXN2L,IL12A,TM6SF1,MMP16,NUMA1,OGG1,PALM,PDE4B,PFKFB4,PPP5C,TMEM231,RAD51D,RNASE1,SEMA6D,SLC11A1,FAIM2,COBL,MCF2L,GPR161,TMPO,R3HDM1,UBE3A,VAV2,KCNK12,ZNF24,PARP6" Drug 2956_UP Torsemide [56211-40-6]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "MTUS1,PLA2G6,MRTFA,CDC42BPA,MPDZ,CACNA1A,CAPN3,SCARB1,NMT2,SULT4A1,SEC14L5,KIAA0513,ZNF337,TBC1D5,HS3ST2,EDIL3,TNK2,ELAVL4,ETV1,KIAA1109,FOXG1,KHDRBS3,NSG1,GABRA2,GATM,PADI2,VWA5A,BCAS3,PTPRN2,FAM120C,RAD52,MYH14,STUM,SLC1A7,LIMCH1,TMCC1,ZHX3,IZUMO4,SPART,SYN2,MTCL1,CAMSAP2,PDLIM2,ATP13A2,SLC17A7,KAT6A" Drug 1210_DN alpha-estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADCY6,BIN1,APBB2,PPFIA3,ARRB2,ZFYVE9,CNTNAP2,SNPH,LPAR6,ERCC2,EFCAB2,TRAF3IP2,HBS1L,ERAP1,GPR37,GUCY1A1,SYNPO,KIF5C,NDP,NFYA,NPR2,STRN3,MBOAT7,PTHLH,RAD52,MAPK12,IL17RB,SH3BGR,FUZ,PEX26,EPN2,FAM214B,CCDC88A,KDM4B,SPATA7,SPTAN1,KIF1B,SYT1,KIAA0930,SYNE1,SIK3,NACC2,TK2,SSBP2,TRIM9,RNF146" Drug 6872_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "BEGAIN,BIN1,CDC42BPA,APP,PPP4R4,EIF4G3,BCL7A,SYNGR3,VAX2,QKI,CRY2,CSF1R,EDRF1,CTIF,CNIH3,LYPD1,RABGAP1L,NCALD,KAT8,SEPT9,RND1,STON1,GPER1,NDUFA5,NF1,EPN1,POU3F4,RIPOR1,RNASEL,ASAP3,BCAN,FAM214B,BTBD7,FAIM2,RBM34,WDTC1,TSPYL2,VPS13A,ATP11A,TRPC1,VAV2,LMF1,KCNK12,ITM2C,ST7,SSPN" Drug 6496_DN Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "KIDINS220,BIN1,APBB2,APLP1,BCAS1,PPFIA3,ALDH4A1,ATP2A2,RIPK1,GYG2,SPAG9,NFS1,CDH10,CACNA2D2,CLU,CREM,GIT2,DBT,JAKMIP2,RABGAP1L,CDON,CINP,MALT1,HNMT,VWA5A,MAP4,SLC11A2,MBOAT7,ELOVL2,FAM120C,RIPOR1,EMID1,SAFB,ZNF821,ELMO2,ZBTB43,CLASP2,TTBK2,AJAP1,ASTN2,EXOC7,PSD3,SSBP2,HIRA,PLPPR2,TIGD6" Drug 442_UP oligomycin; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "SYT13,MRTFA,AQP6,ARNTL,ARRB2,ASCL1,RASL11B,CACNA1I,CAMK2G,INA,ARHGEF2,LY86,IFFO1,GREB1,HS3ST2,ATN1,EFNB3,TBC1D16,TUBB4A,FHL1,ADAMTS13,NR3C1,ICA1,NPY,NRGN,NTRK3,CLDN11,PLXNB1,FSD1,PTH1R,ARHGEF10L,SH3GL3,PKNOX2,SLC11A1,SNAP25,SNCA,TMCC1,ZSWIM8,EMC1,RGL1,EXOC7,SLC35G2,TRPM2,UCHL1,NDRG4,SLC17A7" Drug 4011_UP Fluticasone propionate [80474-14-2]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADD2,CADM3,MTMR3,BAIAP3,MTMR7,CDC42,DLGAP1,PLEKHB1,NCOR2,CSF1R,LRIG1,RIMS2,EXOG,DTNB,CELSR3,RGS17,ETV1,KIAA1109,OGA,FYB1,GABRA3,SIGLEC8,RUNDC3A,GNAL,STON1,HRH3,HLF,ICA1,LMO1,MAN2A2,ADAM11,NF1,NTRK3,P2RX7,RETREG1,BEND5,RTN1,SCN2B,MRAS,FUZ,ZNF334,TNIK,VAMP1,MCF2L,R3HDM1,PHTF2" Drug 5003_DN (-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NDRG3,NME5,SRPX,DGKD,PPFIA3,APP,CDK10,MPDZ,CA12,ARHGEF2,PLEKHB1,QKI,COL9A2,BAG4,CHD1L,RABGAP1L,TRAPPC9,EFNA3,RBM12,IRAK4,ACSL4,INPP5K,GART,MALT1,MAP4,MAPT,GIT1,SLC25A23,LRP12,PRKAR1B,LRRC49,ZFP30,SH3BP2,SMTN,GLT8D1,TSPYL2,TRIM2,RPGRIP1L,ZNF34,TSC2,KLC2,ZNF74,HPS4,MPPE1,SMIM8,ACTR3B" Drug 3932_UP Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADD2,AQP6,ATP2B2,CADM3,ADGRB1,LHX2,STOML1,CTIF,HIPK3,EN2,STX2,ERCC2,EFS,ETV1,FABP7,FLNC,FYN,GAP43,NEU3,GFAP,RUNDC3A,HAS2,SYNPO,MID1,MOBP,NCF2,NEUROD1,TREM2,PFKFB2,CDK14,EPN1,POU3F4,SATB1,STUM,SLC1A7,RIMS1,SNCA,NMNAT2,SYT11,ATP11A,TACR1,WSCD1,CHST5,ZNF154,PAK5,AP3B2" Drug 1493_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AK2,DOC2A,PPFIA3,OSGIN2,SYNGR3,SRSF11,FOXN3,SIPA1L1,DZIP3,CTNND2,DCAF8,HIPK3,SIDT2,SORBS3,EPB41L1,PRKAG2,DPYSL4,SRCAP,NR3C1,IL6ST,MAP4,MIA2,MPP2,PDE3B,SLC25A23,RAD51D,MAPK12,ITSN1,SHANK2,BTBD7,EMC1,ELOVL4,EXOC7,WWC1,TCF7L2,TRIM2,CABIN1,TRPC1,VGF,KLC2,NDRG4,REEP1,FTSJ1,GDPD5,SEMA3B,PHTF2" Drug 2057_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AP4M1,REPS2,CNOT8,TAOK2,KIAA1549L,CHD1L,SH2B1,VCAN,SDC3,PPP6R2,ARHGAP32,SNPH,TM9SF4,RUSC2,KBTBD11,MED12,SLC12A6,MAMLD1,SIDT2,ZNF589,POLR1B,GAD1,PRRC2B,DIDO1,ACOT7,AGFG1,MPP2,SETD4,PC,NLE1,ZNF426,TTLL7,SEC61A2,SUGCT,SBF1,ATXN7,ZKSCAN3,ZNF415,POGZ,MAPK8IP3,EXOC7,MGRN1,TRIM2,UBTF,MPPE1,ACTR3B" Drug 5879_DN Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "CDC42BPA,KCNAB2,ADAM15,MPDZ,TAOK2,NRG2,CNTNAP2,PPP6R2,DBT,EFNA3,MRNIP,EPB41L1,COQ7,ANKMY1,FGFR1,INPP5K,ZNF276,GLRB,HSF2,MAPT,MBD1,TAGLN3,ZNF862,SLC11A2,KCTD15,PPP3CC,SYTL2,SNRK,ELOVL2,RALGDS,ATG16L1,AMBRA1,KBTBD4,CDK5RAP2,LIMCH1,SPATA7,ZBTB43,POGZ,NXT2,VPS13A,PARD3,TRIO,PLPPR2,XRCC4,MAP3K12,KAT6A" Drug 5635_DN Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABHD6,NDRG2,ADRA1D,KIDINS220,AQP4,SYNJ2,GYG2,CRLF1,CHRNB2,STOML1,RCHY1,CSF1R,ARHGEF10,PDE4DIP,RABGAP1L,DRD1,MBNL2,IGSF6,FAM198B,CGREF1,GAB1,GABRA2,GAD2,TMEM8B,ALDH1L1,GLS,TDRKH,LPAR4,GPER1,CACFD1,KCNMA1,MAPT,MMP16,ADAM22,NEK1,NF1,EPN1,RGS10,RASA3,SOX2,DOK5,SPTAN1,CLSTN2,PCDHA5,CADM1,SLC17A7" Drug 5824_DN Meropenem [96036-03-2]; Down 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADD1,ADRA1D,MADD,MARK4,ATM,SPAG9,CBFA2T2,NRG2,SMG7,MED12,FEM1B,SUGP2,EPB41L1,CINP,TRAF3IP2,DISC1,FICD,KLF12,HNMT,INPP5B,MITF,MT1M,NEK1,NFYA,PIK3R1,KCTD15,PLCD1,ZNF426,LRP12,MAPK7,SAMD9,TMEM231,RGS4,BTBD7,SMARCA4,PDZD2,TSPYL2,KAZN,TNS2,TIAM1,TJP1,BHLHB9,METTL3,LMF1,ZNF24,SMIM8" Drug 7141_UP Alprenolol hydrochloride [13707-88-5]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADRB2,APBB2,PDE8B,KYAT1,TAOK2,KIAA1549L,TPP1,DNAJB5,EDRF1,SMG7,DTNA,OPTN,FAM13A,PLEKHA1,ING4,BSCL2,TUBB4A,TESK2,BAIAP2,PDLIM5,FYB1,GAD1,CRCP,RASSF8,INPP5B,JAK2,KIF5C,MAPT,MYO6,NEK1,NF1,SLC11A2,NUMA1,PDE4A,PFKFB2,CDIP1,FA2H,MED1,PEX5,SEC61A2,SCG5,WDTC1,BHLHB9,TRPM2,ZKSCAN5,MICAL1" Drug 6239_DN Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "CDC42BPA,APBB2,EPB41L5,MADD,CASK,ATM,CFLAR,SCARB1,REPS2,SOCS6,AKAP12,ARHGEF10,PPP6R2,ZNF337,GIT2,DBN1,POLR1B,SEMA4D,DISC1,GLS,GPR19,HSF2,KIF5C,L1CAM,MAP4,NCAM2,SETD4,PLXNB1,CNNM2,DCUN1D2,FNDC3A,PEX26,SHANK2,KBTBD4,TMCC1,KDM4B,ANKRD28,TCF7L2,AHCYL2,BEX4,KAT6B,SSBP2,HIRA,RPRM,LMF1,WIPF2" Drug 5423_DN Arecoline hydrobromide [300-08-3]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "RALGAPA1,NME5,C1QTNF3,CDK10,ALDH4A1,SLC4A4,ALDH7A1,CA12,CACNB2,HAP1,CHM,AKAP7,ENTPD4,SH2B1,JAKMIP2,MFAP3L,SORBS3,EPB41L1,PDLIM5,GCNT2,GNG4,HNMT,INPP5B,KCNH2,KIF5C,LSS,TM6SF1,ZNF862,NF1,ELOVL2,RAD51D,RAD52,ASAP3,SLC15A2,SLC20A2,LHPP,INKA2,STX1A,PLCB1,PCDHA6,TGFBR3,HIRA,PLPPR2,MAP3K12,EVI5,SEMA3B" Drug 5057_DN Torsemide [56211-40-6]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ARID1A,EPB41L5,CDC14B,ARNTL,BRINP2,NUMB,ALDH4A1,SYNJ1,SYNJ2,CBFA2T2,PLEKHB1,IQCK,ARMC8,ENTPD4,CREB5,CSF1R,CSNK1E,SDC3,SNPH,RIMS3,DPH1,ING4,TUBB4A,CGREF1,TRAF3IP2,DENND2A,GPR37,BACH2,NDUFA5,NLE1,PEX5,RXRA,DZIP1,PEX26,LIMS2,ARFGAP1,TMCC1,KIAA0930,GPR161,TK2,CADM1,OSBP2,WIPF1,ZNF24,EVI5,KCNAB1" Drug 3249_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASPHD1,ABHD6,PLA2G6,AMPD2,APLP1,PPFIA3,CDK10,BCL7A,CFLAR,QKI,CRY2,PPP6R2,DSCAM,EFNA3,SORBS3,VPS26C,F8,DPYSL4,FAM49B,KIF2A,MPP2,NEK1,NPTX1,NUMA1,OGG1,RETREG1,LRP12,PRKAR1B,RIPOR1,RALGDS,RGS12,ROM1,RPS6KA2,SBF1,SLC20A2,TSPYL2,MAPK8IP3,SEMA4A,PDLIM2,KIAA0930,CRTC1,ZKSCAN5,KLC2,EPM2A,NUP214,ACTR3B" Drug 1933_DN Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "KIDINS220,AP1B1,PLA2G6,APP,NCOA1,MTMR2,ZMYM4,TBRG4,FOXN3,QKI,NIPBL,C2CD2L,EXOG,EFNB3,EIF1,ETV1,TESK2,PDLIM5,ATP6V1H,OGA,PRRC2B,MEF2C,MX1,MYO9A,NAP1L1,SLC11A2,SETD4,CCSER2,PMS2,PPP5C,MAPK7,CNNM2,PTPRE,NCBP3,ATXN2,SUPT20H,PPP1R9A,FAM214B,ZNF430,SMARCA4,SRPK2,TAB2,POGZ,ANKRD12,ATMIN,KAT6B" Drug 590_DN 3-aminobenzamide; Down 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "OGT,APAF1,APBB2,APOC1,CDC14B,ARNTL,ATM,CFLAR,ARHGAP33,CNOT8,TJP2,NCOR1,DRP2,SORBS3,EPB41L2,ZMYND10,PRKAG2,PDLIM5,NEU3,SRCAP,GRB10,PTPRT,ATXN2L,IGF1,ITPKB,NF1,STRN3,PTPRE,RAP1GAP,RASGRF1,TMEM206,RXRA,SELL,SH3BP2,SLA,SLC20A2,SMARCC2,INTS9,SEPT8,SIRT1,KCTD2,TP53BP1,SEZ6L,TMPRSS5,VAV1,ADAMTS9" Drug 6511_UP THIP Hydrochloride; Up 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "BEGAIN,AMPH,GAS7,APOC1,ASPH,ADAM15,CACNB2,CLDN10,PLEKHB1,AKAP5,SLC4A7,ABI3BP,MYRIP,VCAN,TRAPPC9,EFNA3,TENM1,KCNMB2,ZNF589,GAD1,ALDH1L1,GNAL,GPER1,GRM8,SOX21,KLF12,ICA1,KIF5A,MOBP,MSI1,MYO7A,NEFM,SERPINE2,PLCD1,MAPK10,RAB3A,RGS12,GSTCD,SLC1A3,ZNF415,KIF21B,ZBTB43,POPDC3,SEMA4A,RBFOX2,TRPM2" Drug 6410_DN PF-01378883-00 [351320-41-7]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "DPF1,ADORA1,APBB1,APBB2,APP,ARRB2,BAIAP3,BTRC,CBFA2T2,CHI3L2,CLCN3,STOML1,CLTB,WHRN,ABCG1,DSCAM,FAM13A,EGFR,IRAK4,KIAA1109,FGF1,NEK1,PDE3B,PFKFB4,STRN3,MAPK7,GON4L,FAM120C,PEX5,RGS10,SLC1A7,SMARCD3,TNIK,MAPK8IP3,ELOVL4,PLCB1,TAC3,MCF2L,CHST8,PIK3R5,ZMYND8,VAV2,WNT7A,ZNF45,TFIP11,VPS35L" Drug 900_DN 5186324; Down 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "BIN1,NUMB,GPR37L1,QKI,CREM,DCAF8,LYPD1,DLG3,SLC12A6,TNK2,DMTN,LRRC23,F8,FHL1,SEMA4D,EFCAB2,FAM49B,GPD2,GPER1,MAP4K5,JAK2,MAP4,MPP2,GIT1,SMIM7,PMP22,STRN3,MAPK7,CNNM2,TMEM104,PTCH1,ZCWPW1,EMID1,FBXO11,ZSWIM8,EXOC7,PCDHA5,AHCYL2,ZNF34,TIAM1,PARD3,HIRA,VAV1,DNALI1,GDPD5,PHTF2" Drug 6968_DN "estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AK2,CDC42BPA,ADAM15,SCARB1,HOMER3,SMARCAL1,PPP6R2,DCAF8,GIT2,DLG3,MED12,EFEMP1,FAM49B,FYN,SYT17,BTN2A1,HSD17B1,IGSF1,NUCB1,RETREG1,SLC25A23,MBOAT7,POLG,FSD1,PRKAR1B,RAB5B,ARHGEF10L,MAPK12,FERMT1,ABLIM3,SMTN,SMARCC2,CDK5RAP2,WDTC1,FNBP1,NCDN,PDLIM2,TBL1X,PSD3,BEX4,TSC2,ZNF45,NDRG4,PRDM2,GDPD5,MPPE1" Drug 4448_DN trifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AP2A2,APBB2,ALDH4A1,BMPR1B,SCARB1,NRXN3,CLCN4,CNTN1,SH2B1,CSF1R,GPRASP1,G3BP2,EXOG,FAM13A,SUGP2,EPB41L2,BAIAP2,PDLIM5,GNG3,ATXN2L,KIFC3,MAPT,MEF2C,NASP,NDP,NF1,NFYA,PLCB2,TNPO2,PPP5C,WDR25,RGS7,TMEM206,TRAPPC13,SAFB,ZNF821,SH3BP2,FBXO11,BCAN,DZIP1,OGDHL,ARHGAP26,IQSEC2,TNS1,ZNF24,PHTF2" Drug 2913_DN Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "APBB2,BACH1,SYNJ2,MTMR2,CCNT1,CBFA2T2,SOCS6,CHM,NIPBL,SEC31B,SLITRK5,BSCL2,EIF1,ECSIT,ZNF589,FLT1,PDLIM5,ERAP1,IL6R,IPO5,ARHGAP12,MAN2A2,MATK,MKLN1,SLC11A2,NUMA1,ZNF493,NUBPL,PALLD,TNIK,CDK19,PBLD,NCDN,MAPK8IP3,SUPT5H,TCF7L2,AP4E1,ZMAT3,HIRA,ATP6V0E2,REEP1,ZNF225,PRDM2,PRDM10,URM1,EPM2A" Drug 5494_DN Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AP2A2,C1QTNF3,AMPD2,PPFIA3,APP,ALDH4A1,C5,TBRG4,RAB28,CREM,LRIG1,KIAA0586,DBT,DLG3,DSCAM,PLEKHO1,EPB41L2,STX2,FGF12,FHL1,SEMA4D,B4GALNT1,ERAP1,SRCAP,POLL,TDRKH,NUDT21,CLASRP,KLF12,MAP4,MEIS1,NME4,NTRK2,OGG1,PC,PPP5C,NKAIN1,RPS20,ZBTB43,TSPYL2,NXT2,ATP11A,ZNF34,VGF,URM1,SSPN" Drug 3121_UP (1)-Nipecotic acid [498-95-3]; Up 200; 31uM; HL60; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASIC1,ADORA1,AMPH,APBA2,SEMA4G,ARSE,ALDH4A1,ATP2B2,CACNB2,SEPT7,ABCG2,CPS1,CNTNAP2,JAKMIP2,ECM2,CELSR3,SORBS3,SORBS1,SEPT9,MYOZ2,ALDH1L1,GNAL,GPR22,PRDM5,ATXN2L,KCNK1,MAP4,MOBP,LYRM9,TREM2,PFKFB2,DUSP26,PPP2R2B,BCAS3,PTPRH,PID1,MYH14,MAP6D1,FRMPD1,NTNG1,SLC1A3,PALLD,ZSWIM8,WSCD1,AHCYL2,SLC30A3" Drug 1725_UP Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "CDC42BPA,CDK10,PRX,ARNTL,ASPH,OSGIN2,CACNB4,AKAP7,BAG4,AATK,CST3,PITPNC1,HP1BP3,SMG7,MRNIP,RASGRP2,BAIAP2,CAMSAP1,PDLIM5,SEPT9,GART,ALDH1L1,ATXN2L,KLF12,IL6R,ITGA7,KCNJ5,PALM,POLG,PTX3,ATXN2,KBTBD4,SNCA,MAPK8IP3,PDLIM2,TBL1X,DOCK9,PHF24,PARD3,SEZ6L,TMPRSS5,FLRT1,PLPPR2,UPF3A,MAP3K12,ST7" Drug 6079_DN Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AP2A2,PPFIA3,ATP6V0A1,BCL7A,C5,QKI,CNTN1,FEZ1,PDE4DIP,MAML1,DBN1,DBT,EFNA3,ZNF589,FER,FGF12,FOXG1,IQCG,ALDH1L1,GLYR1,POLL,GNAS,GNG3,INPP5B,KCNMA1,RETREG1,LRP12,LRRC49,PTCH1,RAB3A,ZNF821,PEX26,FAM214B,SLC6A8,MAPKBP1,WDTC1,ZCCHC24,KDM4C,LHPP,MAPK8IP3,PLCB1,KAZN,EXOC7,TK2,CABIN1,LMF1" Drug 575_DN copper(II) sulfate pentahydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ARRB2,SLC4A4,CFAP410,CDH8,SULT4A1,ARHGEF6,CDC42BPB,HINFP,PPP6R2,ECE2,SPATA2,C2CD2L,KLHL3,RABGAP1L,E2F5,BAIAP2,SEC23B,SMC2,PDLIM5,HBS1L,ZMYND11,BTN2A1,SYNPO,KCNJ5,IPO5,GIT1,MYT1,NOVA1,NPTX1,NRGN,NUMA1,CDK18,CCSER2,EPN1,SMIM7,PPM1B,GAL3ST4,KBTBD4,SMARCD3,KDM4B,GLT8D1,EMC1,TBL1X,CRB1,ZIC1,MPPE1" Drug 6456_UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADORA1,ARHGDIG,PDE8B,CADM3,ADGRB1,HOMER3,PICK1,PDE4DIP,ATN1,EGR3,RASL12,AGAP2,TMEM8B,SOX21,HTR5A,ICA1,JAK2,KCND3,KCNJ5,KCNMA1,KIF5A,MAOB,MOBP,ADAM22,NDUFA5,NF1,OPCML,PTAFR,ELOVL2,ZSCAN2,C1orf54,ZNF493,RYR1,SYBU,SNCA,ACSBG1,ASTN2,POPDC3,TBCEL,WSCD1,DICER1,AP4E1,TK2,VAV2,SLC30A3,NT5M" Drug 1280_DN Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ANK2,CAMK2G,AP4M1,TPP1,HOMER3,ZNF337,CTIF,RHOBTB1,SMG7,MED12,EEF1A2,MRNIP,PCOLCE2,SCML2,FGFR1,DISC1,SEPT9,VSIG4,IRF8,INPP5B,MAP4,NRGN,NUCB1,OGG1,PPP2R5C,ARHGEF10L,DGLUCY,DZIP1,FAM214B,SPTAN1,MLC1,SEMA4A,SYNE1,AHCYL2,R3HDM1,PARD3,KAT6B,TNNT1,CABIN1,RBFOX2,UBTF,NPDC1,UPF3A,PRDM2,GDPD5,HPS4" Drug 1277_DN Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NDRG2,PLA2G6,PPFIA4,CDK10,ARNTL,ASPH,NCOA1,CFLAR,SPAG9,CCNT1,SOCS6,SMARCAL1,SEC31B,FEZ1,CTIF,DBT,SMG7,EZH1,RACK1,GLS,CACFD1,CLASRP,SLC2A6,LSS,NEFH,KCTD15,SAMD9,MRPS18A,ATXN1,HSPA4L,KDM4B,ZCCHC24,CAMTA2,TTBK2,NSFL1C,VAMP1,TCF4,TCF7L2,AHCYL2,SLC44A1,CABIN1,TNS1,ZMYND8,WNK1,NT5M,GDPD5" Drug 7255_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "BIN1,CNTNAP1,PPFIA3,MADD,MPDZ,CFLAR,CA12,CLCN3,CLU,ARHGAP32,ZFYVE16,EIF5,EPB41L1,ETV1,FGFR1,IP6K2,ANKFY1,EFCAB2,SESN1,RASSF8,MMP16,SETD4,PCDH9,CCSER2,SLC25A23,PTPN13,TMEM231,PID1,ATG16L1,LGR4,BTBD7,TTC17,ZNF415,FCHO1,NCDN,EXOC7,AGTPBP1,TRIM2,PSD3,AHCYL2,CABIN1,TRPC1,TSC1,SSBP2,FAM155A,ITM2C" Drug 3059_DN Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ADORA3,MTUS1,SRPX,BIN1,FAM131A,ATP2B2,ATP6V0A1,CHRNA4,CLCN4,STOML1,NCOR2,PDE4DIP,PPP1R16B,ARHGEF4,EXOG,ATN1,EDNRB,EFNB3,MBNL2,ELAVL3,DLC1,TRAF3IP2,GCNT2,AHDC1,GPM6B,KCNJ5,MID1,AFDN,PDE4D,RAB3A,RALGDS,ZNF821,FRMPD1,EPN2,SNCA,MAPK8IP3,TBL1X,DMXL2,TCF7L2,PSD3,ARHGEF12,THRA,KCTD2,TRPS1,KCNAB1,JPH3" Drug 309_UP sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ARRB2,DNAH17,EIF4G3,NRP2,MTMR3,TJP2,DBI,DBN1,DTNA,EFNB3,EPB41L2,FGFR1,DCTN2,B4GALNT1,GLS,BTN2A1,KHK,KIF5A,STMN1,MAP4,MAPT,PTOV1,NFYA,NPPA,NPR2,SETD4,ENPP2,RETREG1,PLCD1,RIPOR1,PLEKHB2,ARID4A,GAL3ST4,CASC3,FNDC3A,ST6GAL1,SLC20A2,TROVE2,CLSTN2,IQCE,WASHC4,TNS2,CRTC1,ATP13A2,TRIO,SLC17A7" Drug 7254_DN Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "MRTFA,ASPH,MPDZ,LHX2,WHRN,CSNK1E,SDC3,GPRASP1,DLG3,EFNB3,SUGP2,SORBS3,PLEKHA1,ING4,USPL1,SPEG,EZH1,ANKFY1,EFCAB2,DPYSL4,INPP5K,SRCAP,GRB10,SLC2A6,LRRC49,KIRREL1,AMBRA1,SLC6A8,CCDC88A,KBTBD4,ELMO2,SMARCC2,PDZD2,WDTC1,EXOC7,DNMBP,FBXW11,TNS2,TK2,TNS1,MAP3K12,VPS35L,WIPF2,MPPE1,PDSS2,TIGD6" Drug 507_UP SC-58125; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "KDM5D,NDRG2,ALK,EPB41L5,PDXK,ARHGDIG,PDE8B,BMP7,B4GALT6,RAB28,FAM189A2,RIMS2,KLHL3,SRGAP3,DSCAM,OPTN,KCNMB2,ERBB4,ETV1,FGF1,FGFR1,C1orf61,FAM49B,B3GAT1,GABRA4,ZNF44,GNG4,ADAMTS13,ADAMTS6,KCNH2,NCAM1,NNAT,NPY,OPCML,PALM,PDE1C,KLK6,SH3GL3,KBTBD4,CDK19,SYT11,TAC3,HIF3A,CRB1,R3HDM1,RPRM" Drug 2890_DN "Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASPHD1,EP400,BCL7A,ST3GAL5,COL9A2,ENTPD4,ABCG1,CSNK1E,DLG3,IRAK4,PCOLCE2,ENO2,EZH1,DISC1,GOLGB1,GSN,INPP5B,ITPKB,MAP4,MAPT,MBD1,SCAMP5,MPP2,ADAM22,SLC11A2,PC,PRPH,CNNM2,TMEM104,RIPOR1,ZSCAN2,TMEM231,ROM1,FOXRED2,ANKRD6,ABLIM3,ELMO2,RBM34,WDTC1,THSD1,VAMP1,EXOC7,TCF7L2,TRIM2,VGF,EMSY" Drug 3805_UP Fenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "PRX,DNAH17,CFAP410,MTMR7,KCNAB3,CHGB,STOML1,TMEM59L,FAM149A,CSF1,DBT,SPOCK3,ARNT2,USH1C,EDNRA,CELSR3,MBNL2,LRRC23,OLFM1,LYVE1,GNAL,FAM107A,HPCA,KCNN1,KHK,MGAT3,MYCN,NF1,NRCAM,PDE2A,GPR85,SPATA6,PTPRH,SYNDIG1,RTN1,CNKSR2,SHANK2,KIF13A,PDZRN3,CDK19,MAPK8IP3,SEMA4A,TF,TRH,VAV2,KCNAB1" Drug 1208_UP "estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "SEMA7A,APBB1,PPFIA3,MADD,MARK4,ATP2A2,NRP2,B4GALT6,SULT4A1,WHRN,CSF1R,PARD6A,SPOCK3,DPH1,B4GALNT1,GPD1,ATF7,GRIK5,GSTM5,TJAP1,IL6ST,ITGA7,LAMA2,MBD1,NRGN,NTRK2,OPCML,PDGFRA,MAPK7,WDR25,RGS4,MYH14,GSTCD,SUPT20H,SOX10,IZUMO4,NCDN,SEPT8,ARHGEF9,SYT5,MCF2L,AP4E1,VLDLR,TFIP11,SEMA3B,PHTF2" Drug 1901_UP Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "NDRG3,ADCY6,AMT,PPFIA3,NUMB,SLC4A4,ATP2B1,OSGIN2,PTBP2,MAP7,KRIT1,SOCS6,FAM189A2,APPL1,C2CD2L,DTNA,EFNB3,C3orf18,EML1,SEC23B,STAG2,TMEM8B,CRCP,GLS,PTPRT,HPS5,KLF12,IL6R,GIT1,NFYA,NUCB2,CLDN11,ZNF426,PPM1B,ARID4A,NUDT11,SH3GL2,LIMCH1,KLHL7,PRRC2C,FBXW11,TMOD1,UBE3A,EVI5,MPPE1,PLSCR4" Drug 2109_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AQP4,CFLAR,LDLRAD4,CHM,DNAJB5,AKAP7,SLC4A7,CSF1R,PDE4DIP,FCF1,MBNL2,ELAVL2,DMTN,CDKL3,EZH1,FOXG1,C1orf61,SEMA4D,FAM49B,GABRA2,TDRKH,GPR17,STON1,MAP4K5,IL6ST,MDFI,GIT1,NDUFA5,PTPRN2,PEX5,ACSS3,GAL3ST4,RFX2,RGS4,SELL,BCAN,SNCA,SOX10,TIAM1,TMOD1,MAP3K12,PRDM2,NT5M,STMN4,NUP214,RNF146" Drug 5506_DN Proguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AP2A2,AP1B1,ALAD,APP,ARHGAP5,LHX2,IQCK,CREM,MICAL2,TBC1D5,MAMLD1,EFNA3,SUGP2,EGFR,IRAK4,MRNIP,F3,FGFR1,FHL1,FAM49B,GAD1,INPP5K,SPACA9,LMO2,GIT1,NEK1,NPR2,RC3H2,PTK2,NKAIN1,RAD51D,RAD52,BSDC1,RGS10,RNH1,GSTCD,FERMT1,PPP4R3A,EPN2,SCMH1,CAMSAP2,TCF7L2,SIK3,CHST8,ZNF384,KAT6A" Drug 1554_UP Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ALCAM,NRP2,TMEM184B,ARMC8,SLC4A7,CHD1L,SEC31B,AATK,SLITRK5,C2CD2L,SGSM2,TRAPPC9,DPH1,TRAF3IP2,ALDH1L1,MALT1,RUNDC3A,COPS8,DIDO1,ICA1,IL6R,ITGAM,MAP4,NEFH,NUCB1,NUMA1,P2RX7,PDE3B,NLE1,PLCB2,MBOAT7,TMEM104,ZSCAN32,ARID4A,TRIM68,SAFB,FUZ,AMBRA1,ELMO2,EHBP1,PHF24,AHCYL2,KLC2,ZFAND5,PRDM2,SNX27" Drug 5617_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ABHD6,NME5,SEMA6A,APBB2,SYNJ1,RCBTB2,SLIT2,ZFYVE9,BAG4,NECTIN3,SH2B1,ATRNL1,SIPA1L1,PDE4DIP,ZNF804A,LYPD1,FAM198B,CAMSAP1,GABRA2,HBS1L,DISC1,ALDH1L1,MALT1,SLC2A6,INPP1,KITLG,ZNF862,NEK1,PCDH9,PLXNB1,LRP12,PRKAR1B,TMEM104,FBXW7,FBXO11,SLC15A2,BTBD7,KDM4B,WDTC1,THSD1,IQCE,DMXL2,PSD3,PARD3,FAM155A,REEP1" Drug 5866_DN Estriol [50-27-1]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "AMPD2,APOC1,PPFIA3,APP,MARCH3,ZBTB10,SLC4A4,CFLAR,C5,CCNT1,CNOT8,FADS2,ARMC8,NRG2,CNTNAP2,KIAA0513,DBT,PARD6A,TNK2,EPB41L1,FHL1,COPS8,GSN,SYNPO,MBD1,MYO9A,ZNF862,NOVA1,CCSER2,SLC25A23,ZSCAN32,AMBRA1,SHANK2,GLT8D1,SPTAN1,SRPK2,MAPK8IP3,STX1A,PDLIM2,PARD3,RBFOX2,TRIO,MAP3K12,VPS35L,URM1,ITM2C" Drug 3944_UP Sulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "PLA2G6,ADGRF5,APAF1,KCNAB2,GAS7,PROM1,CACNA2D1,AKAP5,ARHGAP24,DCT,FAM13A,ANKMY1,CORO2B,FGFR1,CAMKK2,ATP8A2,GRM7,AP4S1,GUCY1A1,KLF12,ITGAM,KPNA5,MDFI,MID1,PDE1B,POU3F4,C1orf54,PNMA8A,KCNIP1,RYR1,SATB1,ST6GAL1,CNKSR2,SLC1A7,FAIM2,PDZD2,CAND2,NPAS3,JMJD6,TEK,DNAH7,CHST5,VSNL1,SLC13A3,XRCC4,PRDM2" Drug 6092_DN Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "ASIC1,ARID1A,NME5,ALCAM,APBA2,ARRB1,ADAM23,GYG2,CFAP410,NEURL1,REPS2,ADGRG1,CHRNB2,LHX2,CRY2,CTH,RIMS2,DRD1,TOM1,EGFR,ANKMY1,FGF12,FOXG1,PRELID3A,SYT17,GNAS,GNG3,GRM1,IL6ST,KCNF1,NDUFA5,PLXNB1,GRAMD1C,ZDHHC14,SLC1A7,FAM214B,BTBD7,SMARCD3,RBM34,ZCCHC24,MAPK8IP3,TK2,CABIN1,TPM1,VIPR2,SSPN" Drug 7211_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 3.92E-03 1.00E+00 2.18E-02 2.48E-01 46 199 "EPB41L5,PDXK,CDK13,CFLAR,C5,SCARB1,QKI,PDE4DIP,RUBCN,DCAF8,DBT,DCTN1,C2CD2L,FEM1B,PLEKHO1,STX2,EFEMP1,POLR1B,INPP5K,MSL3,BRINP3,INPP5B,IPO5,NCAM2,NRGN,OPA1,PDE4A,RIPOR1,RIC8B,SLC15A2,ERC1,ZBTB43,SRPK2,CLASP2,ELOVL4,STXBP1,NSFL1C,ARHGEF9,ASTN2,KAZN,EXOC7,IQCE,TCF7L2,DOCK9,METTL3,SF1" Drug CID006918457 laulimalide Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 13 38 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,HSP90AA1,TUBB2B,ABCB1,PTK2,SALL1,TUBB2A,TUBB1,TUBA1A" Drug CID000002935 GAMs Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 13 38 "GRIA1,GRIA2,GRIA4,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM3,NUCB1,OPRL1,RNH1" Drug CID004369485 S H Y Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 13 38 "ACTN2,ADRA1B,CFL2,MED12,ATN1,MYH7,NPTX2,SEPT4,PDLIM2,TNNT1,TPM2,TPM3,SMUG1" Drug CID000011606 AC1L1XPX Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 13 38 "ADCY2,ADCY5,ADCY6,ADCY8,APP,NRP2,GAD1,GAD2,GAP43,MX1,PROX1,DDN,ADHFE1" Drug CID000011060 23 B Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 13 38 "MTUS1,SEMA6A,CDK13,VCAN,BOC,EIF1,NSG1,NF1,TCEA1,SYNE1,TIMP4,TSC1,PORCN" Drug CID000131613 MtT-S Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 16 51 "AK2,ATM,CDK5R1,CRYBB1,CS,AK5,CASP8AP2,EGFR,F8,WIF1,KITLG,NF1,RASA3,SST,ARHGAP9,THRA" Drug CID000178036 Finrazole Stitch 3.93E-03 1.00E+00 2.18E-02 2.48E-01 16 51 "AZGP1,CBR1,DTNB,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,MALT1,KCNH1,MBNL1,PRKCG,CASC3,FNDC3A,UBC" Drug 4018_UP Niclosamide [50-65-7]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 3.99E-03 1.00E+00 2.21E-02 2.52E-01 40 168 "ZSCAN18,ZBTB10,CARS,CBS,ARHGEF2,CDC42,CTH,EDRF1,HDAC9,NR1D2,ECM2,EGFR,RGS17,ZNF391,KIAA1109,PRELID3A,OGA,RND1,FERMT2,CACFD1,IFI16,IL12A,MDM4,MIA2,PDE4D,PTX3,BEND5,RGS4,SLC25A36,GSTCD,AP1AR,CPEB3,DOCK10,ZBTB43,ANKRD12,HEY1,CDK20,VIPR2,ZNF24,DPF3" Drug CID000000160 prostaglandin F2 Stitch 4.01E-03 1.00E+00 2.22E-02 2.52E-01 66 306 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,AGT,NR0B1,PLA2G4C,PDE8B,ALDH7A1,CACNA2D1,CBR1,SCARB1,CHRM1,CSF1,PLCXD3,EDN1,EDN3,EDNRA,EDNRB,DHRS4,CRCP,HPGDS,PLCD4,PTGDR2,HRH3,TNFAIP8L3,IGF1,ASPRV1,MSR1,NOS1,NPY,NPPA,OLR1,OXTR,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PLCB2,PLCD1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,PYGM,ELP2,PEG10,SST,PLCB1,TAC1,TAC3,HHIP,PRRT1,PLD4,NETO1" Drug 7221_DN Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ASPHD1,CDC42BPA,NUMB,KIF1A,CFLAR,RAB29,SCARB1,SLC4A7,SIPA1L1,DZIP3,GREB1,DNAJC6,FBXL5,PARD6A,DTNA,IRAK4,MRNIP,COQ7,EZH1,EFEMP1,FGFR1,TXNL4A,COPS8,KCNMB4,BTN2A1,MAP4,MTR,NRGN,PDE4A,C1orf109,RIPOR1,RAB5B,SUSD4,GTDC1,SMARCC2,CEP68,VAMP1,EXOC7,DNMBP,TCF7L2,PSD3,AHCYL2,CABIN1,MPPE1,MVB12B" Drug 7481_DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "BRAP,PKP4,APBB2,CFLAR,AKAP7,BAG4,HINFP,EDRF1,DAPK3,GIT2,C2CD2L,MED12,DTNA,EFNA3,APH1A,DMTN,EZH1,MALT1,GRB10,HNMT,KIF5C,SCAMP5,NEK1,NF1,NFYA,SETD4,ELOVL2,RAB3IL1,FAM184A,ZCWPW1,RGS10,SLC6A8,KDM4B,SOX3,CLASP2,FCHO1,PLCB1,TACC1,TBL1X,TCF7L2,CHST8,HIRA,ZNF184,EMSY,ST7" Drug 7354_DN Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ASIC1,CDC42BPA,APOC1,PPFIA3,CDK13,CFLAR,ST3GAL5,SYNJ2,SCAPER,SCARB1,MAGI1,QKI,ENTPD4,CSNK1E,GPRASP1,DBT,LYPD1,EFNB3,COQ7,ANKMY1,KAT8,ANKFY1,GLYR1,MSL3,ITPKB,KCNH2,MAN2A2,NASP,STRN3,PTCH1,RAD51D,GSTCD,SH3BP2,ZNF365,WDTC1,CLASP2,CEP68,ASTN2,SEMA4A,IQCE,CLASP1,AHCYL2,ZMYND8,MAP3K12,KCNAB1" Drug 3747_DN Flunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ADRA1D,C1QTNF1,ASPH,ALDH4A1,SLC4A4,CFLAR,SYNJ2,CCNT1,ARHGEF2,NRXN3,CHD1L,CPS1,KIAA0513,C2CD2L,DLG3,EDN1,MBNL2,PNMA2,AGFG1,SHISAL1,JAK2,MAP4,ZNF862,NFIX,NUCB1,ODF2,BCAS3,PTHLH,BEND5,TTLL7,KIRREL1,FBXW7,DZIP1,KDM4B,CEP68,SYT1,CAMSAP2,EHBP1,TRIM2,GPR161,THRA,TMPO,UGT8,LAT2,NSD2" Drug 409_UP 2-propylpentanoic acid; Up 200; 1000uM; HL60; HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NDRG2,ASCL1,MARK4,NCOA1,UBE2L6,CLCN3,TMEM184B,FEZ1,DOCK4,DBN1,C2CD2L,EDIL3,SIDT2,EFNB3,FGFR1,POMT1,FYN,GRIK5,IFI16,IGF1,KIF5C,NF1,NRGN,CCSER2,MAPK9,RIPOR1,RLBP1,RPS6KA2,ITSN1,SMTN,KIF21B,ZSWIM8,EMC1,KIF1B,TSPYL2,SRPK2,STXBP1,TCF4,ZEB1,TP53BP1,SEZ6L,PLPPR2,KLC2,LMAN2L,PDSS2" Drug 5914_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "TRMT9B,APBB2,APC,SEMA4G,PLA2G4C,ASCL1,MARK4,BRINP2,KSR1,CDK5R1,CACNA1I,CD86,LHX2,STOML1,FADS2,CSNK1E,EGR3,ELAVL2,IGSF6,RRAGB,FER,CAMSAP1,GPR19,ICA1,IL6R,KHK,MID1,PALM,PENK,RET,RGS3,TCP11L1,ZNF365,SLC4A3,SLC2A5,EPN2,ARHGEF40,SLC11A1,CEP68,IQCE,TNS2,TGFBR3,TNS1,CDK20,SPHK2" Drug 4822_DN Seneciphylline [480-81-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "MTUS1,EIF4G3,ATP2B1,MTMR2,RAB29,SLC25A14,IQCK,ARMC8,CREM,NCOR1,LRIG1,APPL1,CTH,USP6NL,NR1D2,RBM12,TUBD1,EZH1,EFEMP1,SEC23B,FERMT2,BTN2A1,IPO5,ARHGAP12,MBNL1,RC3H2,SYTL2,PTPN13,PCMTD2,TCP11L1,TRAPPC13,SH3BP2,ITSN1,ZNF430,SLC15A2,SLC20A2,TTC17,MTCL1,TCF7L2,TPD52,HIRA,PLPPR2,CLDND1,REEP1,EVI5" Drug 4952_DN Benzthiazide [91-33-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ACTN2,ANK3,APC,CDK10,MADD,ARRB2,CAPRIN2,ALDH4A1,CFLAR,C5,QKI,AKAP7,DCAF8,DAPK3,DBT,SMG7,DTNA,SORBS3,ANKMY1,INPP5K,TDRKH,DHX35,KIF5C,MAPT,KITLG,MPP2,ZNF862,NF1,NFYA,NUMA1,PLCD1,PLEC,STRN3,PTHLH,ZDHHC14,RGS10,CCDC25,FOXRED2,AMBRA1,SMARCA4,WDTC1,SS18,EXOC7,ATP13A2,BEX4" Drug 1556_UP Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NDRG2,AP1B1,BEGAIN,RASL11B,CADM3,BARD1,ST3GAL5,CAST,CLDN10,SLC4A7,ZEB2,C2CD2L,NR1D2,SIDT2,SORBS3,IGSF6,ETV1,PRKAG2,NEU3,PCDH17,RUNDC3A,GNG3,MAN1B1,AGFG1,ITGAM,GIT1,NELL2,CLDN11,PDE3B,CDIP1,PPP2R5C,ARHGEF10L,SLA,ELMO2,SON,DOK5,ZSWIM8,ST5,PHLDB1,MLC1,TCF4,R3HDM1,REEP1,CAMK1G,AAAS" Drug 7260_DN Ethamivan [304-84-7]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "BIN1,MADD,ATM,MPDZ,CFLAR,WHRN,NCOR1,SDC3,DCAF8,GIT2,DBT,SPATA2,KIAA0753,SGSM2,TMCC2,TRAPPC9,TNK2,EML1,ST3GAL6,POLR1B,POMT1,PDLIM5,FAM49B,TPK1,ARFIP1,HTATSF1,CACFD1,BTN2A1,RNFT2,HNMT,IFI16,KHK,TAGLN3,SETD4,CCSER2,MINDY2,TMEM104,ATG16L1,MCMBP,SMARCC2,DOP1A,ARHGEF12,CABIN1,TRPC1,GDPD5" Drug 3379_UP Luteolin [491-70-3]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ADORA1,KIAA1324,DDX3Y,N4BP2L1,CACNG1,GPR37L1,SLC22A6,TPP1,WHRN,ARHGEF10,CNIH3,SPOCK3,SRGAP3,TMCC2,SHANK1,ABCC9,EGR3,LRRC17,ERCC2,CDKL3,PIPOX,CAMSAP1,HBS1L,SESN1,ZNF276,GPER1,MID1,ZNF862,SERPINI1,PLCB2,SMIM7,TNPO2,CEP41,PTX3,RPS20,PAQR6,SCG5,MAPK8IP3,SYT11,EXOC7,ZEB1,PCDHGA10,ZMAT3,SEMA3B,KCNAB1" Drug 2828_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ACTN2,AP2A2,C1QTNF3,BIN1,PPFIA3,MARK4,CACNA1A,HAP1,ARHGEF2,RCBTB2,CLU,CSF1R,ARHGEF10,CTIF,SGK2,ELN,NCALD,DLC1,FGF12,BAIAP2,MSL3,ELOVL5,INPP5B,KCNQ3,MAN2A2,MAP4,MIA2,ADAM22,BCO1,MYO7A,ZNF862,SLC11A2,NTRK2,PCDH9,PACSIN1,PRKAR1B,PRODH,SH3BP2,EPN2,SOX3,DMXL2,DICER1,UBE3A,VAV2,PRDM2" Drug 1827_UP Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ASIC1,LTBP4,CASK,ARRB2,ATM,MPDZ,HIP1R,CLGN,CHN2,CNOT8,ZFYVE9,PDE4DIP,DCAF8,DBT,HP1BP3,RBM12,FAM13A,APH1A,USPL1,EPB41L2,ZNF589,USP21,TPK1,DLL3,ARFIP1,STON1,EML4,MBNL1,MX1,CNOT4,PRPH,CNNM2,RBBP6,RPS6KA2,NCBP3,LMBRD1,CEP68,JMJD6,KIAA0930,TIAM1,METTL3,TRPC1,TST,HIRA,EMSY" Drug 3509_DN Levocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ADCY6,KIDINS220,AP2A2,AK2,PLA2G6,CDK13,RASL11B,ALDH4A1,BTRC,VAX2,ABI3BP,BAG4,SH2B1,CSF1,MAML1,TRAPPC9,RCAN1,RBM12,EZH1,BAIAP2,IP6K2,CINP,ERAP1,CNTRL,HSD17B1,MAP4,MBD1,MSRA,NPTX1,PLEC,SLC25A23,SMIM7,RAD52,GTDC1,SH3BP2,FUZ,LIMCH1,MAPKBP1,TTBK2,PHLDB1,POPDC3,EXOC7,FBXW11,ATP13A2,ZKSCAN5" Drug 1060_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ABHD6,ARID1A,ADD3,EP400,APOC1,ARNTL,ALDH4A1,ATM,BCL7A,LRBA,LRRFIP1,SLC4A7,NCOR1,SGSM2,DNM1,MED12,DTNA,TSPAN5,EFNA3,CELSR3,EIF5,FHL1,PDLIM5,SEPT9,AHDC1,GFER,GOLGB1,GSN,MAP4,OXTR,ARHGEF10L,SUPT20H,ITSN1,PEX26,SLC6A8,SLC20A2,ZNF302,ATP13A2,BHLHB9,WBP2,ZMYND8,CADM1,UBTF,NDRG4,WIPF2" Drug 6722_DN Benserazide hydrochloride [14919-77-8]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "APP,ARRB2,ALDH4A1,ADAM15,CFLAR,SYNJ2,MTMR2,CHM,IQCK,TBC1D5,HP1BP3,DLG3,FCF1,FAM13A,MBNL2,SORBS3,ZNF589,FER,KIAA1109,ANKFY1,PDLIM5,USP21,DENND2A,GCNT2,ARFIP1,GUCY1B1,LIG4,CNOT4,ODF2,PKM,STRN3,FAM184A,RGS10,RPS6KA2,ASAP3,FNDC3A,SLC6A8,CCDC88A,ELMO2,NCDN,UBTF,LMF1,NSD2,KLC2,AAAS" Drug 1233_DN rosiglitazone; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "SHROOM2,BCHE,ST3GAL5,IL33,LHX2,RAB28,WHRN,ABI3BP,CREM,PDE4DIP,SNPH,RIMS3,SIRPA,MED24,TMCC2,DLG3,EFNA3,SORBS3,RGS17,EZH1,POMT1,AHDC1,GLYR1,PSRC1,GPR19,GPR37,SYNPO,NUMA1,PCDH9,GRAMD1C,TRIM68,ZFHX4,MAPK12,CSRNP3,ATXN1,FAM102A,ZKSCAN3,PDZD2,SPATA7,TTBK2,KIAA1107,PARD3,SSBP2,EPM2A,SENP7" Drug 3932_DN Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "AMPD3,APC,PPP4R4,MARK4,SLC4A4,CACNA1D,CBFA2T2,ARHGEF2,CHM,CNTFR,AKAP7,ARMC8,SLC4A7,RCHY1,CSF1R,DMPK,DTNA,EDNRA,HIPK3,FCF1,EPB41L2,EZH1,GPR153,RND1,GPER1,EML4,SPACA9,CACFD1,NR3C1,HSF2,IL6ST,MAPT,MMP16,ADAM22,NF1,PFKFB2,PTHLH,FNDC3A,EMC1,ATP10B,ARC,DICER1,TRIO,ZNF24,PHTF2" Drug 5869_UP Pyrilamine maleate [59-33-6]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ADRB2,APP,PPP4R4,NRP2,RAB29,CFAP410,CDC42,QKI,RAB26,SH2B1,CSNK1E,VCAN,DTNA,TOM1,DUSP9,EFNB3,MBNL2,HSD17B14,EPB41L2,DENND2A,GAD1,HBS1L,ZMYND11,KCNN1,LIG4,MATN3,AFDN,MMP16,MOBP,NTRK2,PMP2,RGS7,KCTD17,NEK11,SCN2B,SLC1A7,TMCC1,ZHX3,SS18,TEX15,TRIO,CA14,LAT2,NT5M,MVB12B" Drug 4492_DN Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NME5,APBB1,APOC1,SEMA4G,ALDH4A1,KIF1A,BACH1,ADGRB2,BTRC,CACNA2D2,FOXN3,AKAP7,ABCG1,DAPK3,PARD6A,SPOCK3,SIDT2,AASS,SPEG,KIAA1109,GABRA2,POLL,GPM6B,SYNPO,KIF2A,KIT,MAPT,MDFI,NNAT,PRKAR1B,MAPK7,PID1,RAD52,RGS10,ZNF821,BCAN,SLC11A1,IQSEC2,DDN,TAL1,GPR161,TMOD1,TNS1,STMN4,NUP214" Drug 3679_UP Flurandrenolide [1524-88-5]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ADD2,DNAH17,PTCH2,SLC4A4,ATP6V0A1,BMP7,MTMR3,GYG2,CACNA1I,CDK5R2,CFAP410,CACNA2D1,CACNB2,CAMK2B,ADGRG1,CHI3L2,NRXN3,SLC24A2,AKAP12,EFNB3,ZNF549,NRN1,GRIK5,IL6R,MATN3,NF1,NOVA2,NTRK3,NUMA1,P2RX7,MTRF1L,PTN,ZSCAN2,RAD52,RIMS1,SNAP25,SNCA,SOX15,PLCB1,SEMA4A,MCF2L,TAL1,TK2,NAV2,NLRP3" Drug 7065_UP SC 19220; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "APAF1,APC,PPFIA3,ALDH4A1,STX16,MTMR9,SLC25A14,CPS1,VCAN,DZIP3,RIMS3,DAPK3,RUSC2,PARD6A,RCAN1,EGFR,ING4,SCML2,DLL3,FYB1,TRAF3IP2,SLC2A6,MIA2,SCAMP5,TAGLN3,NUMA1,PBX1,PIK3R1,CDIP1,PPP5C,PRKAR1B,MAPK7,ZSCAN32,RAD52,TCP11L1,SNCA,ZNF415,SS18,JMJD6,ATP11A,WWC1,ARHGEF12,TRIO,WNT7A,PHTF2" Drug 2221_DN Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "OGT,CDK10,ASPH,ATM,CAMK2B,CAMK2G,SCARB1,HOMER3,AKAP7,CSF1,CSF1R,PDE4DIP,SEC14L5,TBC1D5,RIMS3,KIAA0586,CDON,SIDT2,ERBB2,INPP5K,GLYR1,RAB30,GLS,GNG4,GRIK5,GSN,MUM1,ICA1,ITPKB,LSS,MYO7A,NPR2,PLEC,ZSCAN2,ROM1,EMID1,SH3BP2,PEX26,PDZRN3,KDM4B,UNC5B,ATP11A,TMOD1,TPD52,ZNF74" Drug 1642_DN chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "AP2A2,CDC42BPA,PKP4,PPFIA3,BCL2L2,WASF1,NFS1,SOCS6,DZIP3,CTNND1,CTNND2,DCAF8,HDAC4,TBC1D5,SGSM2,SIDT2,EML1,DENND4A,TRAF3IP2,WASF3,ZNF276,CNTRL,BTN2A1,ARHGAP19,IL6ST,ITPKB,JAK2,NFYA,RETREG1,PRKAB2,GON4L,PTPRG,MAP6D1,SFPQ,KBTBD4,ZKSCAN3,ZBTB43,TROVE2,POGZ,MAPK8IP3,SIN3B,KIAA0930,LMF1,WIPF2,NUP214" Drug 6553_DN 5194442; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NDRG3,AMT,ASPH,ATM,STX16,ARHGEF1,NRXN3,CLU,RAB26,CPS1,DZIP3,PARD6A,EDIL3,EDNRA,FCF1,CNNM1,LRRC23,ZNF589,FER,PDLIM5,CSPG5,SYT17,ZNF276,COPS8,CNTRL,HNMT,IL6ST,MSR1,NF1,NFIX,CNOT4,PLEC,FAM120C,ATG16L1,KIRREL1,MAPK12,FBXO11,KBTBD4,ZNF415,IZUMO4,FBXW11,WSCD1,TMPO,HIRA,RPRM" Drug 6031_UP N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "SYN3,MTUS1,NME5,LTBP4,GAS7,ARHGDIG,GYG2,CHGA,EPS15L1,CNTNAP2,INTS1,BRINP1,CNIH3,CHRDL1,EDN3,EBI3,VPS13B,ATP8A2,MYOZ2,RUNDC3A,GPM6A,TJAP1,MAOB,MEF2C,AFDN,ADAM22,SLCO1C1,OMG,OPCML,ENPP2,LRRN3,PTAFR,RGR,ZNF415,ARHGAP26,SYT11,TBCEL,DOCK9,PCDHA2,UCHL1,FLRT2,ZNF74,STMN4,HRASLS,PAK5" Drug 1341_UP Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "ABAT,NDRG2,APBB2,STX16,BACH1,SCAPER,SCARB1,CLCN4,DBT,DLG4,DTNA,FCF1,EIF5,PTK2B,CAMSAP1,FHL1,C1orf61,DISC1,GLYR1,MSL3,POLL,GPR19,KIF2A,NF1,OGG1,PIK3CD,CCSER2,POU6F1,PTPA,RAB3IL1,DPF2,DCUN1D2,FOXRED2,SUPT20H,TMCC1,DOP1A,IZUMO4,SS18,EXOC7,ZEB1,TRPS1,ZNF32,URM1,UBE3B,NLRP3" Drug 428_DN 17-AAG; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "RBM10,OSBPL1A,CDC42BPA,ADAM23,ADAM15,SYNJ2,HAP1,C2CD2L,SMG7,DLG3,DSCAM,SIDT2,EPB41L2,STX2,TUBB4A,FGFR1,SEPT9,MCHR1,PTPRT,NXPH3,SCIN,KHK,MYO7A,SLC11A2,NTRK3,CCSER2,PLEC,RETREG2,PRKAR1B,MAPK3,RAP1GAP,RET,ZNF821,SLC2A5,KBTBD4,WDTC1,TSNAXIP1,NMNAT2,ZC3H13,CEP68,TMPRSS5,UBTF,VAV2,NSD2,SLC26A10" Drug 6955_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "C1QTNF3,BBOX1,BIN1,CAPRIN2,ASPH,CFLAR,ARHGAP33,FADS2,QKI,CSF1,PDE4DIP,KIAA0513,RUSC2,RABGAP1L,ATN1,DTNB,EDN3,COQ7,CACFD1,ADAM22,NDUFA5,PCDH9,PLEC,PROX1,RAD52,UEVLD,SEC14L1,TSNAXIP1,DOK5,ZHX3,IQSEC2,CLSTN2,MAPK8IP3,VAMP1,CRTC1,AHCYL2,TK2,PIK3R5,CADM1,OSBP2,VAV1,ZNF24,PRDM2,UBE3B,SMIM8" Drug 258_UP LY294002; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NDRG2,LTBP4,BIN1,ARNTL,CADM3,ATP6V0A1,SYNJ2,MTMR2,CHN2,CLIP3,ABCG1,SIDT2,MBNL2,ING4,F5,ATP2C1,STON1,GRIN1,KIF3A,PADI2,NXPH3,HNMT,KCNJ5,ADAM22,NAP1L1,NF1,RETREG1,EPN1,PPP2R2B,LRRN3,PPP5C,ZSCAN32,CCDC40,FAM184A,GAL3ST4,GSTCD,PPM1E,NMNAT2,MAPK8IP3,GANAB,FAM208A,PCDHA5,TRIO,WIPF1,MPPE1" Drug 3021_DN Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "NDRG3,ADORA3,MRTFA,CDC42BPA,NCOA1,NRP2,MAP7,CLGN,B4GALT6,ZFYVE9,EEF1A2,FAM13A,COQ7,RASGRP2,DLC1,CAMKK2,CSPG5,GABRA4,SEPT9,ADAM28,LILRA2,NCKAP1L,ITGAM,KCND3,MAPT,TM6SF1,NNAT,DEF8,PTPRB,MARCH1,RAB3A,ZCWPW1,SYNDIG1,MYH15,ZCCHC24,UNC5B,RAP1GAP2,ZC4H2,EXOC7,TCF7L2,TNS1,TPM1,ZMYND8,GDPD5,KCNAB1" Drug 7468_DN Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "OSBPL1A,CDC42BPA,MTMR2,EPS15L1,FEZ1,GREB1,PPP6R2,DCAF8,DSCAM,MAMLD1,FEM1B,EPB41L2,COQ7,GPR153,ERAP1,GLS,GPD2,ARHGAP19,MAPT,MBD1,MITF,SETD4,OGG1,POLG,MED1,RAB3IL1,RXRA,FERMT1,FBXO11,WDR47,SHANK2,ZKSCAN3,IFT122,ZBTB43,ARHGEF9,ATP11A,TACC1,WWC1,TRIM2,AHCYL2,ZMYND8,VIPR2,LMF1,ZNF24,SMIM8" Drug 2621_UP Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "TTYH1,C1QTNF1,BIN1,CDC42BPA,APC,PPP4R4,MARK4,NUMB,ALDH4A1,SLC4A4,CFAP410,P2RX6,CHI3L2,TAOK2,FADS2,CNTN1,AKAP7,AATK,CSF1,ATRNL1,CTNND2,INTS1,DCT,MFAP3L,OPTN,EIF4G2,DLC1,SEMA4D,GAD1,SRCAP,RND1,ITPKB,KCND3,MEF2C,ZNF862,NHLH1,NLE1,POU3F2,MED1,SAMD9,SLN,ZCCHC24,SPTAN1,HIRA,SEMA3B" Drug 1947_DN Hesperetin [520-33-2]; Down 200; 13.2uM; PC3; HG-U133A Broad Institute CMAP Down 4.02E-03 1.00E+00 2.22E-02 2.52E-01 45 194 "RBM10,ABHD6,ADD1,AP1B1,APC,APP,PDXK,ARHGEF1,CNOT8,SOCS5,PPP6R2,C2CD2L,RCAN1,DTNA,PLEKHA1,EXTL2,BAIAP2,ATP2C1,CACFD1,NR3C1,MAP4,NF1,PDE1C,SMIM7,MYH14,NCBP3,SUPT20H,HSPA4L,FAM102A,URGCP,SLC11A1,SCMH1,NMNAT2,UNC5B,ATP10B,ANKRD12,TCF4,DMXL2,TCF7,TCF7L2,CBX5,TRIO,KLC2,PRDM2,MPPE1" Drug ctd:D015647 "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine" CTD 4.05E-03 1.00E+00 2.24E-02 2.55E-01 39 163 "NDRG2,ADCY5,CAMK2B,NFS1,INA,CDC42,CFL2,HECTD1,CNN3,GDA,DPYSL2,DRD1,GAD1,GLUL,GNAO1,GRIN1,ACOT7,HNRNPK,IDH3A,TAGLN3,NPY,PCMT1,PDYN,TMOD2,PACSIN1,SIRT2,NAPB,SNAP25,SNCA,SEPT8,SEPT3,SYN1,ARC,SYN2,SYT1,TAC1,TPM2,TPM3,HNRNPA3" Drug CID000003449 NSC100058 Stitch 4.06E-03 1.00E+00 2.24E-02 2.55E-01 21 74 "ACHE,ALS2,APP,PRX,BCHE,CHRM1,CHRNA4,CHRNB2,ABCG1,GCNT2,GK,CNDP1,GRIN2C,GRIN2D,KCNB1,MAOB,MGAT3,MTTP,ST6GAL1,SNCB,MGAT5B" Drug ctd:C058317 arsenic disulfide CTD 4.06E-03 1.00E+00 2.24E-02 2.55E-01 21 74 "OGT,BID,HOMER3,ZFYVE16,SV2B,STX2,EVL,GLUL,GRIN1,GSN,KIF3A,ITGAM,MDM4,PKIA,PEX5,RTN1,SLC1A2,DDHD2,SIRT1,ZKSCAN5,PRDM2" Drug CID000072124 siguazodan Stitch 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "ADRB2,ALDH7A1,IGF1,JAK2,PDE3A,PDE3B,PDE4B,PDE4D,TAC1" Drug ctd:C032904 "2,2',3,5',6-pentachlorobiphenyl" CTD 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "GABRA1,GABRG2,NR3C1,WIF1,MBP,NRGN,MAPK3,RYR1,SIRT1" Drug CID003037130 Acth(11-24) Stitch 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "CLTC,ENO2,TUBB3,FGF1,GAP43,CLIP1,SST,TRH,CLIP2" Drug CID000008135 AC1L1QCE Stitch 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "CLTC,CP,BOC,MID1,NME4,ROM1,SNCA,SPP1,PORCN" Drug CID000008174 panorama Stitch 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "ABHD6,SOCS5,HEPH,PCSK1N,KCNH1,NDUFA5,ADHFE1,CNTN2,SLC13A3" Drug CID009897422 SureCN13401588 Stitch 4.09E-03 1.00E+00 2.26E-02 2.57E-01 9 22 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUB,TUBB1,TUBA1A" Drug 6003_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "DDO,PLA2G4C,ATP1A2,LDLRAD4,CACNB2,RCBTB2,SOCS6,FAM189A2,SLC4A7,ARHGAP24,SPOCK2,EGR3,DMTN,ERCC2,DLC1,FGFR1,DKK3,GAB1,ATP8A2,POLL,LPAR4,GSN,SLC2A6,PTGDR2,CD200,ADAM22,NPY,NOVA2,NPTX1,PDE4D,PIK3CD,C1orf54,RGS12,SBF1,SH3BP2,ZCCHC24,TRIM2,PSD3,TRPC1,VAV2,MICAL1,LAT2,ADAMTS9,ITM2C" Drug 865_UP C768-0445; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "SYT13,APBB2,ADGRB2,CA4,CDH10,CSF1,RGS6,MICAL2,GREB1,SLC12A6,ST8SIA3,ING4,EPB41,ANKMY1,AGAP2,GAB1,NEU3,STON1,LPAR4,CNTRL,NR3C1,GRM8,KCNMA1,ADAM22,NF1,ZSCAN2,RAB3IL1,C1orf54,ZFP30,FRMPD1,ZNF365,EPN2,FAM214B,SOX2,SOX3,UHRF1BP1L,ZBTB43,MAPK8IP3,KIAA1107,TF,TLR4,TRIO,VAV2,KCNAB1" Drug 1232_DN troglitazone; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "CDC42BPA,MPDZ,IL33,KYAT1,CLCN4,NIPBL,ABI3BP,DLG3,DNM2,EDN1,EZH1,F3,TESK2,FGF1,GLYR1,GPR37,CNTRL,KLF12,MAP4,MEF2C,PC,POLG,PPP2R5C,SAMD9,SYTL2,TRIM68,CSRNP3,ATXN1,SUPT20H,FAM102A,ASAP3,DOCK10,ATF7IP,WDTC1,SPATA7,KDM3A,CDK19,CAMTA2,PSD3,XRCC4,ZBTB38,NAV3,ST7,SENP7" Drug 1307_UP Corticosterone [50-22-6]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "ABAT,ABHD6,ADORA3,APBB2,APC,BACH1,SYNJ1,C5,CD86,SLC4A7,BAG4,CHD1L,CREM,VCAN,NR1D2,DMTF1,RCAN1,HIPK3,EGR3,ING4,ERAP1,COPS8,GLYR1,MSL3,GPR19,MPP2,NF1,CNOT4,OGG1,PDE3B,PLCD1,RC3H2,MINDY2,PPM1B,SUPT20H,SPP1,SAMSN1,NXT2,FAM168A,CAMSAP2,EHBP1,DMXL2,MARCH8,UBE3B" Drug 5586_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "ADORA2A,OSBPL1A,AMPD3,BIN1,B3GALT2,BACH1,CA4,CACNG1,CBFA2T2,DNAJB5,ABI3BP,NRG2,CPS1,PDE4DIP,SPOCK2,ELMO1,RCAN1,DYRK1A,EDNRA,ING4,TNK2,OLIG2,SORBS1,SEPT9,GNAL,NR3C1,IL6R,KCNH2,KIFC3,AFDN,MYO7A,NAP1L2,PCDH9,SERPINI1,PLXNB1,MAPK7,TTLL7,HSPA4L,SH3BGR,SOX15,POPDC3,PCDHGA10,TRPM2,VLDLR" Drug 3788_DN Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "AMPD3,SEMA7A,BTRC,CANX,CHM,CLCN3,DNAJB5,CNTNAP2,EXOG,EDIL3,HIPK3,FCF1,FAM13A,FGF1,SORBS1,OGA,GPD2,RASSF8,KPNA5,MAP4,MBNL1,ADAM22,NF1,ODF2,PIK3R1,ZCWPW1,ATXN1,TNIK,TAB2,SYT1,TBL1X,EHBP1,TCF4,TCF7L2,ZEB1,TIAM1,TMPO,TRIO,VLDLR,LAT2,XRCC4,PRDM2,KAT6A,PHTF2" Drug 3214_DN "Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "PLA2G6,DOC2A,APBB2,PPFIA3,APP,ARHGDIG,ARNTL,MARK4,BTRC,USP2,QKI,HOMER3,WHRN,CREM,CTNND2,MRNIP,CDKL3,BAIAP2,USP19,DBF4,PSRC1,EML4,HSF2,MAP4,MATK,MITF,GPSM2,PLXNB1,SPDL1,RGS12,NEK11,MAP6D1,EMID1,TRA2B,ZFP30,SMTN,ZKSCAN3,KDM4B,SPTAN1,JMJD6,ZNF34,TMPO,KCTD2,XRCC4" Drug 1646_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "ANK3,ALDH4A1,CFLAR,BTRC,CA4,HAP1,FOXN3,SH2B1,FEZ1,CSNK1E,CTH,TBC1D5,SPOCK2,DPH1,DSCAM,DTNA,ING4,ANKMY1,ZNF589,FGFR1,IQCG,INPP5K,MSL3,POLL,GPER1,PADI2,ICA1,KITLG,NEK1,NFYA,NUMA1,PPP2R5C,PPP5C,NEK11,SOX10,CEP68,PLCB1,TBL1X,ZNF34,CABIN1,RBFOX2,UBE2H,EMSY,MARCH8" Drug 3770_DN Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "ASIC1,CDC7,NME5,APC,ARHGAP22,LHX2,PLAA,SMARCAL1,TENM4,SIPA1L1,SLITRK5,DCAF4,ARMCX2,RHOBTB1,SGSM2,FEM1B,EIF5,FGF1,DCTN2,GPM6B,GPR19,GUCY1A1,ITPKB,VWA5A,ZNF862,SETD4,RETREG1,SAMD9,WDR25,ZSCAN32,RAB3A,SH3TC2,RPS6KA2,MAP6D1,ST6GAL1,ZNF365,FAM214B,GLT8D1,ASTN2,KIAA1107,RPGRIP1L,TNS1,ZNF32,HPS4" Drug 6717_DN Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.11E-03 1.00E+00 2.26E-02 2.58E-01 44 189 "MTUS1,PDE8B,ASPH,SYNJ2,MYRF,CHM,RAB28,ENTPD4,CNTNAP2,TBC1D5,HP1BP3,EXOG,FCF1,SPEG,ETV1,ZNF589,FGFR1,IQCG,ANKFY1,GLYR1,GLS,HNMT,IL6ST,KPNA5,NDP,CNOT4,TMEM231,FAM184A,TRAPPC13,SAFB,MAPK12,SLC20A2,LIMCH1,EMC1,NXT2,ZEB1,DNAH7,SSBP2,UBTF,NSD2,XRCC4,MPPE1,UBE3B,PHTF2" Drug CID000024417 S-methylcysteine Stitch 4.13E-03 1.00E+00 2.28E-02 2.59E-01 12 34 "CBS,KYAT1,CDO1,FOXG1,MTHFD2,HMGCR,MSRA,PAH,RNH1,GSTCD,TRERF1,DDN" Drug CID000002073 NSC15627 Stitch 4.13E-03 1.00E+00 2.28E-02 2.59E-01 12 34 "CACNB2,ASIC3,KCNA2,KCNA4,KCNB1,KCND2,KCNH2,PACRG,MYL3,SCN4B,SLC11A1,SCN3B" Drug CID006328106 triethyllead Stitch 4.13E-03 1.00E+00 2.28E-02 2.59E-01 12 34 "ALAD,CACNA2D1,DTNB,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TBL1X,TUBB1,TUBA1A" Drug CID000107927 5-hydroxypropafenone Stitch 4.13E-03 1.00E+00 2.28E-02 2.59E-01 12 34 "ASIC1,ADRB2,ASIC3,KCNH2,NDP,ABCB1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug 7490_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.19E-03 1.00E+00 2.31E-02 2.63E-01 43 184 "DPF1,AK2,CDK13,PDE8B,SLC4A4,SYNJ2,CA12,CBFA2T2,CHN2,PLEKHB1,GREB1,CTIF,TMCC2,ATN1,RASGRP1,EGR3,PIPOX,FER,GPR153,TRAF3IP2,RASSF8,SYNPO,INPP5B,JAK2,KIT,NKAIN1,RET,MYH14,GSTCD,FBXW7,MAP6D1,IL17RB,SGK1,PPP1R9A,SYBU,COA1,LIMCH1,KDM4B,SOX15,ARC,WSCD1,SLC44A1,UCHL1" Drug 3244_UP Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.19E-03 1.00E+00 2.31E-02 2.63E-01 43 184 "C1QTNF1,LTBP4,APBA2,APBB2,PPP4R4,RGS20,ST3GAL5,CBFA2T2,RCBTB2,SOCS6,CHRNB2,RIMS2,DTNA,MBNL2,EPB41L2,IGSF6,GALC,SRCAP,GPM6A,STON1,GPER1,GPR37,NR3C1,HMGCR,INPP5B,VWA5A,ZNF862,SLCO1C1,NUMA1,PCDH9,SERPINE2,PLCD1,STRN3,ELOVL2,SLC2A5,ZNF423,TACC1,TBCEL,SZT2,PCDHA5,TMOD1,RUNDC3B,KAT6A" Drug 5530_UP Parthenolide [20554-84-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.19E-03 1.00E+00 2.31E-02 2.63E-01 43 184 "PLA2G6,APC,PPFIA3,CFLAR,SPAG9,CREM,DAPK3,MFAP3L,DSCAM,PLXNC1,LRRC17,RASGRP2,CDKL3,BAIAP2,AMOTL2,IP6K2,ATP2C1,SRCAP,SESN1,CACFD1,NR3C1,BTN2A1,IL6R,IL12A,LIG4,ZNF862,SERPINI1,SMIM7,NECAB2,C1orf54,SH3BP2,TNIK,KDM3A,ZBTB43,JMJD6,ROBO3,R3HDM1,CA14,ZKSCAN5,UBE2H,ZNF45,WNK1,RNF146" Drug 7059_UP "Forskolin, from Coleus forskohlii; Up 200; 0.5uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.19E-03 1.00E+00 2.31E-02 2.63E-01 43 184 "GRAMD1B,MARK4,SYNJ1,IL33,MAP7,TAOK2,WHRN,TCEAL2,ENTPD4,AKAP12,NCOR2,CTH,ARHGEF4,ARHGAP32,ZNF337,PITPNC1,ARNT2,EDIL3,EN2,GPR153,ERAP1,SEPT9,GPER1,SHISAL1,NFYA,PBX1,PDE4B,SMOX,CDIP1,FA2H,MAPK8,PTAFR,PTHLH,CEP97,RBBP6,RXRA,EPN2,WDTC1,NCDN,KIAA1107,WSCD1,AHCYL2,SEMA3B" Drug CID006918335 eleutherobin Stitch 4.26E-03 1.00E+00 2.34E-02 2.67E-01 11 30 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,STMN1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID000119346 Ne 2 Stitch 4.26E-03 1.00E+00 2.34E-02 2.67E-01 11 30 "CDO1,LY86,HEPH,NCKAP1,PTPN5,INPP1,PMP2,RNASE1,RPE,SAFB,ADHFE1" Drug CID000017648 thiocolchicine Stitch 4.26E-03 1.00E+00 2.34E-02 2.67E-01 11 30 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,SP2,TUBB2A,TUBB1,UBE3A,TUBA1A" Drug CID000003604 hexamethonium Stitch 4.26E-03 1.00E+00 2.34E-02 2.67E-01 35 143 "ACHE,ADRA1D,ADRA1B,ADRB2,AGT,BCHE,CACNA2D1,CCK,CCKBR,SOCS6,CHRM1,CHRNA4,CHRNB2,GAL3ST1,DBI,DMPK,DRD1,EDN1,EDN3,B3GAT1,INPP5K,CRCP,HRH3,HNMT,NOS1,NPY,OPRL1,PDYN,PENK,SST,TAC1,TAC3,TACR1,TRH,VIPR2" Drug CID000003486 glutathionesulfonic acid Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 22 79 "SLITRK1,APP,RGN,B4GALT6,LRIG1,CNTNAP2,EARS2,DAPK3,DRD1,EN2,FKTN,BAIAP2,KCNA1,KCNA2,NPTX1,NRGN,GTDC1,SLC1A2,SLC1A3,SLC6A1,ROBO3,MAP3K12" Drug CID000091867 "2,4-difluorobenzyl alcohol" Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "CALB1,CALB2,QKI,VCAN,CHRDL1,PPP1R1B,PLP1,SYNE1,ARHGAP9,TF" Drug CID000352796 NSC527981 Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "TUBD1,TUBB3,TUBB4A,TUBA8,LYVE1,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000002929 indibulin Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "EGFR,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,ABCB1,TUBB1,TUBA1A" Drug CID000119137 Septide Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "CALB1,SULT4A1,BOC,B3GAT1,NOS1,OPRL1,PSMA6,TAC1,TAC3,TACR1" Drug CID000127736 desethyl KBT-3022 Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000001330 DPSPX Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,AGT,ALDH7A1,PDE3B,TAC1,ZIC3" Drug CID003283967 AC1MP8YQ Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 10 26 "C5,STX2,OLFM1,NBL1,RDX,PBRM1,SP2,TAC1,TAC3,TRPC3" Drug CID000000846 kynurenine Stitch 4.26E-03 1.00E+00 2.35E-02 2.67E-01 28 108 "ABAT,BIN1,AMT,PDXK,KYAT1,SULT4A1,EBI3,GTF2IRD2,ATP8A2,GPT2,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM8,IL17D,OGDH,ETNPPL,TRIM9" Drug CID000002936 AC1L1ET5 Stitch 4.28E-03 1.00E+00 2.35E-02 2.68E-01 19 65 "CACNA1E,CAPN3,CAST,FGFR1,FOXM1,INPP1,ITPKB,KCNH2,KCNJ4,MAPT,PDGFRA,PRKCB,PRKCG,LAMA1,SLC8A1,SNCA,TRH,PLD4,NUP214" Drug CID000002012 AC1L1CQC Stitch 4.28E-03 1.00E+00 2.35E-02 2.68E-01 19 65 "ASIC1,CACNA2D1,CBR1,ASIC3,CHRM1,PHYHIP,ERBB2,KCNH2,OPRL1,ENPP2,ABCB1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TNNT1,PMEPA1" Drug CID000003938 S-(-)-Lisuride Stitch 4.28E-03 1.00E+00 2.35E-02 2.68E-01 19 65 "ABAT,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,CHRM1,HDAC4,DRD1,DTNA,DMTN,LOXL3,HTR2A,HTR5A,MAOB,SOX10,MLST8,TRH" Drug CID000191080 AC1L4RU2 Stitch 4.28E-03 1.00E+00 2.35E-02 2.68E-01 19 65 "SERPINA3,KIF1A,ENO2,TUBB4A,PNMA2,B3GAT1,MBD1,KITLG,MT3,NAP1L3,NCAM1,CLDN11,RAB3A,FBXW7,SOX10,SYP,SYT1,TSC1,HPS4" Drug 4762_UP Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.28E-03 1.00E+00 2.35E-02 2.68E-01 42 179 "RALGAPA1,SEMA6A,ALCAM,APBA2,LGR5,NRP2,CA4,ARHGEF2,CLGN,CLCN4,COL9A3,RCHY1,MBNL2,VPS13B,FABP7,AMOTL2,OGA,FYN,ERAP1,TMEM8B,NEU3,GRB10,ADAMTS13,HPSE2,ICA1,LAMA2,MIA2,PGAM2,PRKCB,C1orf54,EMID1,PPM1E,SLC6A9,LIMCH1,KIF21B,TSNAXIP1,KDM3A,TRIM2,BCL2L13,VLDLR,LAT2,SENP7" Drug CID000003278 ethacrynic acid Stitch 4.29E-03 1.00E+00 2.36E-02 2.68E-01 34 138 "ADCY2,ADCY5,ADCY6,ADCY8,SLC12A5,ATP1A1,SLC4A4,KIF1A,SGCE,CA4,CA12,CBR1,SLC22A6,ABCC5,EDNRA,KIF3A,GSTM5,GSTT2,HMGB1,KCNK3,KIF2A,KIF5A,KIFC3,ABCB1,MAPK3,KIF7,GSTCD,KIF27,KIF21A,KIF16B,SLC12A4,KIF13A,KIF1B,TBL1X" Drug CID006335488 Lucifer yellow Stitch 4.30E-03 1.00E+00 2.37E-02 2.69E-01 29 113 "ACHE,MIER1,BCS1L,CALB1,CALB2,RGN,CD86,CLTC,GPHN,GFAP,GJB1,GRIK1,NCAM2,P2RX7,ABCB1,GPSM2,PRKCB,PRKCG,PKN2,PRKCZ,PTCH1,SYN1,SYN2,TF,CHST8,CDK20,TPM3,PORCN,GJC2" Drug CID000005772 Lypressin Stitch 4.31E-03 1.00E+00 2.37E-02 2.69E-01 15 47 "ACHE,ADCY5,ADCY6,ADCY8,AGT,ALAD,PLCXD3,PLCD4,OXTR,PLCB2,PLCD1,DDN,SST,PLCB1,TRH" Drug CID000016591 APDs Stitch 4.31E-03 1.00E+00 2.37E-02 2.69E-01 15 47 "ASIC1,CLCN3,AASS,GRIN1,HTR2A,KCNA1,KCND2,KCND3,KCNH2,KCNK3,KCNN3,ENPP2,GPR85,KCNIP2,NPL" Drug CID002723790 thiourea Stitch 4.33E-03 1.00E+00 2.37E-02 2.70E-01 32 128 "RGS20,CCK,FADS2,HOMER3,SUMF2,BOC,SHANK1,SYT3,FERMT2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,PADI2,HRH3,IGF1,NOS1,PKM,PLTP,FERMT1,SLC8A2,SLC8A3,SHANK2,SLC14A1,CLSTN2,SAMSN1,ADHFE1,TCF12,TF,TST" Drug CID000052999 metsulfuron-methyl Stitch 4.33E-03 1.00E+00 2.37E-02 2.70E-01 31 123 "AMPD2,CNTNAP1,ARRB1,ARSE,CCK,NOG,CHM,CSF3R,DTNB,OS9,GRK4,GRIA1,GRIA2,GRIA4,GRIK1,GRM3,GRM5,ACOT7,NKD1,ITPKB,MSI1,NASP,HCN1,CLDN11,GPR85,RAB3A,RTN1,DDN,NPL,HIRA,SSPN" Drug 1788_UP Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "EP400,PPFIA4,PKP4,MTMR2,CA12,CACNB4,CHN2,JAM2,TAOK2,CPS1,ENTPD4,VCAN,HP1BP3,KIAA0753,DTNA,EFNB3,DMTN,ANKMY1,AFF2,HBS1L,B4GALNT1,GAP43,PCSK1N,ITGA7,ITGAM,MAP4,GIT1,NTRK3,ODF2,OMG,PLTP,PACSIN1,MAPK10,CNNM2,PTK2,FAM102A,AMBRA1,SLC12A2,ELMO2,DOK5,CLASP2,TBL1X,RBFOX2,HIRA,TRIM9,HPS4" Drug 1720_DN Gliclazide [21187-98-4]; Down 200; 12.4uM; HL60; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ADD3,APP,SHTN1,N4BP2L1,WASF1,KRIT1,CCNT1,CNOT8,CLCN3,QKI,SLC4A7,RCAN1,YAF2,MBNL2,KCTD3,DCTN4,ACSL4,FGFR1,SUCO,SEC23B,SEMA4D,PDLIM5,FAM49B,GLS,MAP4K5,MPP2,NF1,NFYA,NTRK2,SETD4,LRP12,PTK2,MYH14,RPS6KA2,CHD9,HECW1,SPART,CLASP2,NXT2,DDHD2,SIRT1,TMPO,LAT2,EVI5,SNX27,EPM2A" Drug 447_DN retinoic acid; Down 200; 1uM; PC3; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "GAS7,ARNTL,SLC4A4,ATP6V0A1,CHN1,TJP2,NIPBL,IFFO1,SIPA1L1,GIT2,AK5,EGFR,BSCL2,VPS13B,EPHB1,EFS,TBC1D16,MPP6,RASSF8,HNMT,AFF1,GIT1,NFE2L2,NTRK3,CLDN11,C19orf57,PTHLH,SPDL1,RALGDS,RAP1GDS1,RGS4,RNF220,RMI1,ZFP30,SNAP25,KDM4B,RAP1GAP2,ATP11A,ANKRD12,MCF2L,TBL1X,TCF4,SEZ6L,UCHL1,SLC13A3,MPPE1" Drug 5230_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ABHD6,EPB41L5,SYNJ2,SCAPER,PLEKHB1,SLIT2,RAB28,SORBS3,LRRC23,FGFR1,PRELID3A,GFER,GPD2,GPM6B,TDRKH,GPR19,STON1,PCLO,INPP5B,MAP4,MDM4,NPR2,PRKAB2,MAPK7,PRPH,RAB3A,CEP97,ARHGEF10L,ASAP3,SLC6A8,BTBD7,SLC22A4,MAPKBP1,SOX2,ZHX3,CLSTN2,KANK1,ATP11A,EXOC7,TRIM2,TMOD1,CABIN1,TRIO,LMF1,GDPD5,SENP7" Drug 6679_DN Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "KIDINS220,APAF1,APC,GAS7,NCOA1,CACNB2,SYNGR3,FOXN3,SOCS6,CLCN4,ARMC8,VCAN,HDAC9,FEM1B,CNNM1,EFNA3,MBNL2,PLXNC1,DMTN,ZNF391,ETV1,IQCG,SEMA4D,FAM49B,GPM6B,VWA5A,MEIS1,NF1,PAX6,LRP12,PRKAR1B,GRAMD1C,GON4L,ZCWPW1,TRAPPC13,ZNF821,ASAP3,FBXO11,PPP4R3A,KDM4C,LHPP,TCF4,DOCK9,TPM2,VGF,SENP7" Drug 2390_UP "Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ALK,SEMA7A,PKP4,BTRC,SEPT7,CDO1,CHM,HOMER3,SLC4A7,AATK,DAPK3,DBN1,PARD6A,SPOCK3,DTNB,DYRK1A,EDIL3,CDKL3,BAIAP2,KHDRBS3,C1QL1,GLS,ATF7,GRM7,ATXN2L,ICA1,KIF5C,MEF2C,NELL2,PBX1,PLCD1,PTAFR,EPN2,SMTN,PALLD,TROVE2,THSD1,ASTN2,PDLIM2,CRTC1,TEX15,CRB1,GPR161,RBFOX2,SSBP2,PCBP4" Drug 1574_DN Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ACTN2,SYT13,NCOA1,N4BP2L1,CFLAR,CAMK2G,PPP6R2,MED24,SGSM2,DTNA,IRAK4,PCOLCE2,VPS26C,CEND1,KIAA1109,SEC23B,ATP2C1,TRAF3IP2,PRRC2B,NFYA,NOS1,SLC11A2,PDE4A,ENPP2,RETREG1,PKN2,RAB5B,RAP1GAP,BSDC1,RET,RFX5,ZC3H14,FAM192A,SLC11A1,ZCCHC24,SS18,GANAB,SUPT5H,VPS13A,TAC3,THBS4,CABIN1,WRN,FTSJ1,ADAMTS9,IFT88" Drug 2989_UP Benzthiazide [91-33-8]; Up 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "GRAMD1B,AMPH,ATP2B3,AZGP1,DGKI,REPS2,CLU,CNTFR,AKAP6,MFAP3L,HIPK3,ZNF589,GAB1,GABRA3,ALDH1L1,ADAM28,RASSF8,ATXN2L,KLF12,KIF5C,SMAD1,MAG,MBNL1,MMP16,MN1,MSR1,NPR2,PCSK5,TNPO2,PPP5C,MASP1,TMEM104,HECW1,LHPP,ARHGEF9,SYN2,SYT1,PHF24,TEK,ATP13A2,ZNF34,TPM3,TRPS1,WNT7A,SLC17A7,SSPN" Drug 988_DN "estradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "OSBPL1A,AK2,MARK4,ATP2B1,CFLAR,SMARCAL1,CRY2,LRIG1,DZIP3,GPRASP1,SGSM2,ATN1,DSCAM,DTNA,HIPK3,EIF5,ING4,SEMA4D,EFCAB2,FAM49B,CGREF1,SRCAP,MALT1,DIDO1,ATXN2L,LIG4,MBD1,MDM4,MMP16,GIT1,CNOT4,OGG1,PDE3B,SSH1,CCDC25,PAQR6,FOXRED2,ANKRD6,SMTN,DIP2A,MICAL1,LMF1,EVI5,HPS4,FIP1L1,AAAS" Drug 5471_DN Allantoin [97-59-6]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ASPHD1,ACTN2,AK2,APBB2,SYNJ2,SCAPER,CACNA1D,CNOT8,CTNND2,DCAF8,DNM2,RCAN1,SIDT2,MRNIP,ENO2,F3,ATP2C1,OGA,PRRC2B,ICA1,KHK,TM6SF1,OCRL,OXTR,PC,SLC25A23,SMIM7,TMEM231,RNH1,PAQR6,FAM214B,ZNF430,RAB3GAP1,SLC22A4,SMARCA4,LIMCH1,SPTAN1,CDK19,PHLDB1,IQCE,TRIM2,ZNF34,TK2,KCTD2,CABIN1,PLPPR2" Drug 3765_DN Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ASIC1,ALK,ADGRB2,BMP7,NEURL1,ABCG2,CRMP1,CNTNAP2,GPRASP1,RIMS3,CDKL3,FGFR1,SYT17,ATP8A2,GNAS,CACFD1,IL6ST,IL12A,NF1,NFYA,ODF2,P2RY1,GRAMD1C,PRPH,WDR25,PLPPR1,ZSCAN32,ACSS3,RAD52,TMEM206,TCP11L1,SBF1,ASAP3,FNDC3A,ZNF667,SNCA,RBM34,LHPP,SAMSN1,THSD1,SZT2,DNAH7,GPR161,WNT7A,SPHK2,SCG2" Drug 5363_DN Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "AK2,ALCAM,DGKD,ATM,CFLAR,BTRC,CBFA2T2,PLEKHB1,NECTIN3,ENTPD4,AKAP12,SOCS5,DBT,HP1BP3,SUGP2,IRAK4,PLEKHO1,BAIAP2,FHL1,GRB10,BTN2A1,MITF,SLC25A23,PRKAR1B,RAB3IL1,CEP97,RAD51D,DCUN1D2,PPP4R3A,SLC15A2,BTBD7,COA1,LIMCH1,MAPKBP1,WDTC1,KDM4C,THSD1,TTBK2,TCF7,TMOD1,CABIN1,CDK20,ZMYND8,EIF4ENIF1,LMF1,ZNF248" Drug 4828_DN Simvastatin [79902-63-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ADCY6,PLA2G6,MAP4K3,APC,CDC14B,PLA2G4C,EIF4G3,CFLAR,MTMR2,SOCS6,RAB28,TMEM184B,AKAP7,CREM,ZFYVE16,GIT2,JAKMIP2,MFAP3L,DENND4A,EFCAB2,GAD1,JAK2,KCNH2,KCNJ3,TM6SF1,PDE3B,RETREG1,POLG,SYTL2,FAM184A,ZNF821,ITSN1,NUBPL,SLC20A2,TTC17,LIMCH1,ZHX3,ATP11A,SEMA4A,IQCE,TMOD1,RBFOX2,WRN,CLDND1,SSPN,RNF146" Drug 7534_UP "ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ADD2,ALCAM,LTBP4,CNTNAP1,SCAPER,GYG2,CA4,SULT4A1,ARHGEF6,AKAP7,PDE4DIP,DZIP3,CTNND2,RASSF2,ZNF804A,DLG2,EDNRA,EGFR,VPS26C,F5,FUT9,GAB1,GNG3,STON1,GRIK4,GUCY1A2,KLF12,HNMT,KCNN2,LSS,NFYA,CNOT4,NPPA,NUMA1,MAPK4,EMID1,SLCO1A2,KDM4C,CLASP2,SS18,PHLDB1,VPS13A,PLCB1,IQCE,PLPPR2,SLC26A10" Drug 1387_UP Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "NDRG3,EP400,PKP4,APAF1,ARRB2,MTMR2,ARHGAP33,ENTPD4,ARHGEF10,PPP6R2,TM9SF4,DBT,TNK2,ERCC2,PDLIM5,CAMKK2,PCSK1N,PRRC2B,MAN1B1,HRH3,AGBL5,KCND3,KIF2A,NEK1,NTRK3,NUCB1,OMG,PLCD1,ZNF426,LRP12,NECAB2,POLG,VPS13C,RAB3A,RNASEL,FBXW7,CLIP1,ATXN7,STUM,SIRT2,SON,IQSEC2,TSPYL2,TNS1,RBFOX2,CA14" Drug 316_DN flufenamic acid; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ABHD6,LTBP4,APBB1,DGKD,APP,ARNTL,ATP6V0A1,CD38,HOMER3,ARHGEF6,ARHGEF10,CSNK1E,SDC3,KLHL3,DRP2,C3orf18,LRRC23,RRAGB,FOLR2,GPR19,GRIN1,ARHGAP19,ITPKB,KCNJ10,NTRK3,RGS3,RGS4,KLHDC8A,RAVER2,KCNIP2,FOXRED2,ARHGEF40,KBTBD4,IFT122,TMCC1,KDM4B,ZCCHC24,ZHX3,IZUMO4,SPTAN1,SEPT8,ZFR2,KAZN,WWC1,NPL,MVB12B" Drug 702_UP alpha-estradiol; Up 200; 0.01uM; PC3; HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "NDRG2,NCOA1,N4BP2L1,LRBA,TBRG4,RNF14,FEZ2,OSBPL3,SOCS5,EDRF1,SPATA2,HS3ST2,CEND1,TESK2,SEC23B,AFF2,HTATSF1,ADAMTS6,GUCY1A1,NUCB1,NUCB2,PDE3B,SPDL1,CCDC40,STUM,FBXO11,ZNF430,SMARCC2,SRPK2,EPB41L3,SS18,NXT2,ST5,NEK4,IQCE,EHBP1,SIK3,TMOD1,SEZ6L,TRPM2,UBE3A,SLC26A10,ZNF142,SLC17A7,SMIM8,CAMK1G" Drug 3640_DN Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "AP2A2,APOC1,ADAM15,HAP1,CAMK2B,SLC16A4,NEURL1,AKAP7,AKAP5,CRY2,GREB1,MFAP3L,CDON,EFNB3,ING4,CEND1,FGFR1,FYN,GAD1,ALDH1L1,GNAS,GPER1,GSN,RNFT2,ITIH2,VWA5A,CLDN11,PLCD1,MBOAT7,RIPOR1,ZSCAN2,KCTD17,GSTCD,ANKRD6,SLC2A5,SLN,DOK5,SPTB,TROVE2,INKA2,PHLDB1,KIAA1107,TBCEL,ARHGEF12,ZKSCAN5,FLRT2" Drug 379_DN cobalt(II) chloride hexahydrate; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "NDRG2,MTUS1,AK2,ALAD,APBB1,PPFIA3,SLC4A4,FUBP1,ZFYVE9,STOML1,PICK1,IQCK,RIMS2,CTIF,HS3ST2,DMTN,LRRC23,KCNMB2,VPS26C,TUBB4A,GPR153,SRCAP,DIDO1,ADAMTS13,SOX21,MAN1B1,KCNJ3,MOBP,MYO7A,NEFH,MBOAT7,SPDL1,RAP1GDS1,RLBP1,URGCP,INTS9,EMC1,ST5,FCHO1,WWC1,TCF4,ARHGEF12,HIF3A,TNS1,SLC26A10,ZBTB16" Drug 666_DN butirosin A from Bacillus vitellinus; Down 200; 10uM; PC3; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "NDRG2,GAS7,APOC1,SHROOM2,ALDH4A1,CADM3,BTRC,P2RX6,AP4M1,FOXN3,LY86,CSF1,EDRF1,KLHL3,DYRK1A,EFNA3,FECH,AHCYL1,GDF9,PRRC2B,PRUNE2,ADAMTS13,ATXN2L,KCNB1,KCNJ5,MYO6,NEK1,OGG1,PC,PTPRE,TCP11L1,RXRA,ATXN2,FUZ,EPN2,SLC11A1,SMARCC2,MAPKBP1,CEP68,IQCE,DMXL2,ZEB1,DAAM2,SEZ6L,CADM1,AAAS" Drug 1238_UP "ICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "BIN1,APC,GAS7,ARNTL,CACNA2D1,SCARB1,ABCG1,CSF1,EXOG,DYNC1I1,DTNA,EFNB3,STX2,BAIAP2,PNMA2,GABRA2,GLI2,MSL3,GRIK5,KLF12,ITGA7,ZNF862,CNOT4,ODF2,PSMD13,PTN,RAD51D,RGS4,NUDT11,SUPT20H,PEX26,PPP4R3A,LHPP,SYT11,SYN2,PDLIM2,SZT2,CRTC1,CABIN1,RUNDC3B,WIPF1,ZNF74,ZNF225,EMSY,STMN4,AAAS" Drug 2157_DN Austricine [10180-88-8]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ACTN2,NDRG2,PPP4R4,ATP2A2,MYRF,CACNA1A,FOXN3,PLAA,CNTN1,SH2B1,PDE4DIP,CTIF,SGSM2,RCAN1,ELN,RASGRP2,CDKL3,F5,AFF2,KHDRBS3,GAB1,SRCAP,USP19,KCNMB4,LILRA2,GIT1,MYT1,NOS1,POU6F1,PPARA,PTPA,ZSCAN32,MYH14,ITSN1,ANKRD6,EPN2,BTBD7,WDTC1,DOK5,JMJD6,PLCB1,DNMBP,PSD3,PARD3,ST7,PHTF2" Drug 1144_UP haloperidol; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "KIDINS220,MRTFA,AMT,APBB2,ARNTL,ADAM15,THSD7A,CAMK2B,FOXN3,CLCN4,AKAP7,CREM,DAPK1,KIAA0753,RUSC2,EGR3,FER,FHL1,C1orf61,CAP2,PDLIM5,ERAP1,SRCAP,GLYR1,SCAMP5,MX1,NEK1,PLCD1,PTN,PTPRN2,RAP1GAP,ZDHHC4,RGS10,MYH14,RPS6KA2,SAFB,SEC14L1,SLC11A1,TMPO,PARD3,TPD52,TPM3,NPDC1,SPHK2,PARP11,PHTF2" Drug 141_DN chlorpropamide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "MRTFA,OGT,ARRB2,MARK4,NUMB,BCL7A,CACNA1I,ARHGEF2,ZMYM4,CSNK1E,CSNK1G3,ARNT2,ABI1,ABI2,BSCL2,CEND1,FGFR1,PDLIM5,SRCAP,SPIN1,GOLGB1,SCIN,MAPT,ADAM22,NRCAM,SETD4,PRPH,ZSCAN32,RPRD1A,CASC3,SH3BP2,FUZ,TMCC1,KDM4B,USP33,EMC1,STX1A,IQCE,DMXL2,CBX5,KCTD2,TRIO,TRPM2,CADM1,LMAN2L,NUP214" Drug 2175_DN Dipyrone [5907-38-0]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "RALGAPA1,BRAP,GRAMD1B,MRTFA,AMPD2,APP,ATP2A2,MTMR2,CACNA1A,SOCS6,COL9A2,C2CD2,ZFYVE16,RUSC2,TNK2,TUBD1,RASGRP2,SCML2,COPS8,GPR22,ITPKB,JAK2,LIG4,MAP4,NEK1,SLC11A2,CCSER2,ZNF426,POLG,PRKAB2,RAB3IL1,GSTCD,TCP11L1,ATXN2,RASA3,FAM214B,SNCA,ZCCHC24,IZUMO4,ZC4H2,PLCB1,PCDHGA10,OBSL1,TPM1,TRPS1,TIGD6" Drug 2082_UP Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "KIDINS220,TRMT9B,MYRF,RCBTB2,NMT2,CLTB,DNAJB5,NIPBL,HOMER3,AKAP7,IQCK,DLG3,FCF1,MTSS1L,ANKMY1,SYT17,GPR17,LPAR4,CACFD1,DHX35,SHISAL1,TJAP1,KCNN1,MAPT,ZNF862,OGG1,MAPK7,RAB5B,C1orf54,KCTD17,NUDT11,RPS6KA2,SLC1A7,SLC6A8,ARHGEF40,SLC22A4,SNCA,CAMTA2,GANAB,SEMA4A,KIAA0930,ARHGEF12,TPM2,ZNF32,PRDM2,KCNAB1" Drug 3062_DN Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "NR0B1,PLA2G6,MRTFA,AMPH,ANK3,APAF1,FAM131A,APOC1,DNAH17,SLC4A4,KIF1A,ARHGEF7,ZFYVE9,BAG4,PPP1R16B,KIAA0753,ELAVL3,COQ7,FHL1,PDLIM5,GAB1,SEPT9,WASF3,GCNT2,LILRA2,ATXN2L,KCNJ5,MAP4,MEF2C,MID1,PDE4A,PLEC,SLC25A23,LRRN3,MAPK8,PTAFR,TMEM231,SCG5,SNCA,WDTC1,SYN2,TCF7L2,SYNE1,TRPS1,SSBP2,SSPN" Drug 7129_DN Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "APC,CFLAR,NIPBL,AKAP7,CREM,TENM4,ARHGAP32,RABGAP1L,SLC12A6,ABI1,EDNRA,PHF20L1,SUGP2,LPAR6,ELAVL2,POLR1B,CAMSAP1,FAM49B,KLF12,IL6R,DIPK1A,MMP16,PBX1,PIK3R1,KCTD15,FSD1,SHANK2,SPATA7,ARHGAP26,NCDN,STX1A,GSE1,TCF4,SATB2,TCF7L2,TRPC1,SSBP2,HIRA,PLPPR2,KLC2,XRCC4,ZNF45,UPF3A,PRDM2,HPS4,URM1" Drug 4638_UP Dioxybenzone [131-53-3]; Up 200; 16.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "IL33,CRLF1,ADGRG1,WHRN,SUSD5,PDE4DIP,CNIH3,PLPPR4,DLG3,SGK2,EFNA3,RASGRP2,FAM198B,FYB1,SIGLEC8,GNG4,PRUNE2,GPM6B,LILRA2,HLF,IGF1,KCNJ5,LSS,PACRG,MBNL1,MIA2,ADAM22,MYO7A,PDE4D,PENK,RC3H2,GDPD2,SNRK,NEK11,SELL,MRAS,SLC2A5,KIF21B,ARHGAP26,RBM26,SLC44A1,TNS1,UGT8,VAV2,MVB12B,DPF3" Drug 3667_UP Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ASIC1,ADRA1D,ANK1,APP,LGR5,CDC14B,ASCL1,SLC4A4,KSR1,CACNG1,CALB2,CHI3L2,RCHY1,IFFO1,CNTNAP2,DCT,ELAVL4,NRN1,ARMCX1,FGR,SIGLEC8,KCNH1,CD200,ADAM22,P2RX7,PBX1,PLP1,GDPD2,PTAFR,ZMAT4,RAVER2,PNMA8A,SH3BP2,NLGN1,SLC11A1,SOX15,INKA2,MAPK8IP3,TAL1,CUX2,ZFPM2,PIK3R5,LILRA4,UCHL1,ZIC3,KCNAB1" Drug 5284_DN Hydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "OGT,APP,EIF4G3,MTMR9,ARHGEF2,CNOT8,CLCN3,NIPBL,CREM,SACS,DNM1,RCAN1,SORBS3,EML1,F8,TESK2,GALC,INPP5K,GRB10,SLC2A6,MAPT,MBNL1,PTOV1,NEK1,PLEC,SMIM7,MED1,PRKACB,BSDC1,REV3L,ARHGEF10L,RXRA,AP1AR,PEX26,SLC15A2,SMARCC2,RCOR3,SPATA7,ZSWIM8,TCF7L2,WASHC4,ATP13A2,TRIO,CADM1,MPPE1,NUP214" Drug 7315_DN Isotretinoin [4759-48-2]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ATM,STX16,ST3GAL5,IL33,RCBTB2,PLAA,QKI,ENTPD4,PDE4DIP,SLITRK5,GIT2,SIRPA,LYPD1,SMG7,ACOT8,IRAK4,COQ7,FGFR1,SCARA3,CGREF1,GCNT2,TXNL4A,GLYR1,GPER1,CNTRL,KLF12,SYNPO,MAP4,TAGLN3,NF1,NPR2,RAB3IL1,RAD51D,SH3TC2,RPS6KA2,ITSN1,SHANK2,ZBTB43,ITPRID2,ELOVL4,VAMP1,ARHGEF12,RUNDC3B,ZKSCAN5,ZNF711,ZNF45" Drug 5772_DN Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "PPFIA3,RIPK1,DNAJB5,QKI,VCAN,SIRPA,DBT,RUSC2,C2CD2L,TOM1,EDNRA,MBNL2,SORBS3,HSD17B14,ERCC2,CDKL3,FECH,FGF13,FGFR1,TRMO,PCDH17,KCNMB4,GPR37,BACH2,TJAP1,NPR2,SLC11A2,PFKFB2,SERPINI1,PTPRH,PEX5,FAT4,BEND5,SUGCT,ZNF821,SUPT20H,FAM102A,TROVE2,PHLDB1,ATP11A,TNS1,TRPC1,NDRG4,NAV3,KCNAB1,GAN" Drug 6789_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "MRTFA,APC,KIF1A,SYNJ2,BTRC,CAMK2G,SLIT2,LHX2,BAG4,CSNK1E,ARHGAP32,GIT2,MFAP3L,SMG7,DTNA,PCOLCE2,FOXG1,DPYSL4,SRCAP,HTATSF1,AGFG1,INPP5B,NF1,SLC11A2,OGG1,PDE3B,RETREG1,PLEC,SMIM7,PRODH,PTCH1,UEVLD,TCP11L1,RXRA,SGK1,RAB3GAP1,SMARCC2,UHRF1BP1L,RBM26,EXOC7,TNS2,TRIO,CADM1,LMF1,PRDM2,PHTF2" Drug 6996_DN fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "CDC42BPA,CDK13,CDK5R1,ARHGEF7,C5,REPS2,PLAA,PPP6R2,ZNF337,B3GAT3,MFAP3L,SMG7,EXOG,SORBS3,TNK2,VPS26C,SEMA4D,FAM49B,ZNF276,FERMT2,GPR37,KCNJ3,MITF,LYRM9,NF1,OGDH,PCDH9,POLG,PPP5C,TMEM104,RAB3A,ZCWPW1,ROM1,FNDC3A,ZHX3,SP2,ZBTB43,TSPYL2,ARHGEF9,TBL1X,BHLHB9,HIRA,VGF,URM1,EPM2A,GAN" Drug 5094_DN Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ADD2,KCNAB2,MARK4,ADGRB2,FUBP1,SLC4A8,SDC3,DAPK3,SMG7,SPOCK3,SGSM2,FCF1,MBNL2,BAIAP2,FAM49B,GAB1,ERAP1,TDRKH,GRM1,AGFG1,KCNN1,LIFR,MAP4,MATN3,MIA2,CNOT4,SMIM7,KLK6,CNNM2,RAB3IL1,RAD51D,ZDHHC14,ZNF671,SUPT20H,PPP4R3A,CCDC88A,ZNF415,PEG10,ARHGEF9,EXOC7,TCF4,LMF1,ZNF711,SLC17A7,KAT6A,AAAS" Drug 6329_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "ADORA1,LTBP4,BIN1,APBB1,CDK13,MAP7,INA,SH2B1,NCOR2,FEZ1,CSNK1E,C2CD2L,RABGAP1L,SIDT2,TENM1,DMTN,KIAA1109,IQGAP2,GLYR1,TDRKH,MIA2,MMP16,NELL2,CNOT4,NUMA1,ODF2,PALM,PACSIN1,PPP1R1A,MAPK7,PLPPR1,SEC61A2,MYH14,ROM1,NEK11,PAQR6,STUM,FAM214B,OGDHL,DOK5,ARHGAP26,LHPP,SS18,ARHGEF12,CRTC1,OSBP2" Drug 6150_DN Ramipril [87333-19-5]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.34E-03 1.00E+00 2.37E-02 2.70E-01 46 200 "KIDINS220,MRTFA,BTRC,CFAP410,ZFYVE9,CTIF,HIPK3,MBNL2,PIPOX,ST3GAL6,TRAF3IP2,SEPT9,INPP5K,WASF3,USP19,POLL,MAP4K5,IL6ST,NDUFA5,SLC11A2,OMG,PDE4A,RETREG1,PLCD1,MAPK8,PTAFR,PTPRO,RIPOR1,ZCWPW1,PAQR6,SH3BP2,SLC2A5,SNCA,ZC4H2,SS18,DNMBP,FBXW11,TNS2,AP4E1,TMOD1,FLRT2,XRCC4,ZNF32,REEP1,EMSY,UBE3B" Drug CID000005711 Y-27632 Stitch 4.38E-03 1.00E+00 2.40E-02 2.73E-01 91 445 "ADRB2,AGT,MRTFA,ANK1,MYH7B,APC,APLP1,APP,ARHGDIA,CFLAR,DST,CALM1,NGB,ARHGEF25,AIFM1,ARHGEF1,CDC42,NOG,CFL2,CHRM1,MYL6B,COL4A5,COL9A1,COL9A2,COL9A3,COL11A2,AKAP12,CALY,CYBB,DAPK3,DPYSL2,EDN1,EDN3,EDNRB,ABI2,PTK2B,ACTL6B,BAIAP2,FOXO3,SEMA4D,MSTN,RND1,STMN2,GRIK1,CIT,GPR45,TNFAIP8L3,SYNPO,HMGCR,MYLK2,MAT2A,GIT1,MYL3,NODAL,NOS1,OLR1,OMG,P2RX7,P2RY1,SSH1,PIK3C2A,PIK3CD,PIK3R1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,PTK2,PTPRN2,RDX,RTKN,MAPK12,MRAS,FNDC3A,SST,MLC1,SYT1,TAC1,WWC1,ARHGEF12,LEFTY2,ACTR6,TP53BP2,TRIO,GORASP1,VAV2,SLC26A10" Drug CID000445950 1h00 Stitch 4.39E-03 1.00E+00 2.40E-02 2.73E-01 17 56 "COL9A1,COL9A2,COL9A3,COL11A2,APPL1,GPRASP1,CHRDL1,DPYSL2,ZMYND10,FER,GAD2,LAMP2,MBNL1,SCN2A,SLC11A1,TNNT1,TP53BP2" Drug ctd:C029310 lard CTD 4.39E-03 1.00E+00 2.40E-02 2.73E-01 17 56 "ACADM,ACLY,HHATL,GPAM,ARHGEF7,CHRNA4,CS,ELAVL2,KCNC2,MYBPC1,NCAM2,OLR1,PPARA,FAM184A,SLC1A2,MYO16,ZIC3" Drug CID000388944 AC1L8WWP Stitch 4.39E-03 1.00E+00 2.40E-02 2.73E-01 17 56 "ABCG2,NCOR1,NCOR2,EGFR,TUBD1,ERBB2,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MAP4,MX1,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug ctd:D002217 Carbachol CTD 4.39E-03 1.00E+00 2.40E-02 2.73E-01 17 56 "ACHE,ADCY5,APP,CHRM1,CHRM4,CHRNA4,CHRNB2,PTK2B,FGF1,FYN,KCNJ3,NPY,NPPA,PRKCZ,MAPK3,PLCB1,SYNC" Drug CID000656979 O-Ln Stitch 4.39E-03 1.00E+00 2.40E-02 2.73E-01 17 56 "ERMN,ARHGAP32,GFAP,GFRA1,GFRA2,RBPJ,MAG,MBP,MOG,PTPA,RET,S100B,SIRT2,SIRT1,TJP1,ZFP91,TUBA1A" Drug CID000000934 nickel Stitch 4.43E-03 1.00E+00 2.41E-02 2.75E-01 110 552 "ASIC1,ADAR,ADCY2,ADCY5,ADCY6,ADCY8,PITPNM2,APLP1,NT5C3B,APP,NRP2,CACNA1I,CACNA1G,CA4,CA8,CA12,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,KRIT1,CD86,CDH2,CDO1,CACNA2D2,CLTC,CNR1,COL11A2,PLCXD3,DMPK,EDN1,EDN3,CACNG7,APH1A,TUBD1,EPB41L1,EPB41L2,ERBB4,EFS,CACNG3,CACNG2,TUBB3,TUBB4A,FGF1,SPSB4,POLK,NRG3,DNER,TUBA8,GGT7,TUBA1C,GRIA1,GRIA2,GRIA4,PLCD4,GRM3,CIT,CLASRP,FAM107A,HBA1,FRMD3,TNFAIP8L3,TUBB2B,KITLG,MID1,NBL1,SLC11A2,ENPP2,ANLN,PKD1,PLCB2,PLCD1,POLG,PPP3CA,PPP3CC,PRODH,REV3L,RNASE1,RPE65,RYR1,RYR3,SCNN1D,COPZ1,NLGN1,SLC8A1,SLC8A3,SLC11A1,SLC14A1,PEG10,EPB41L3,PLCB1,SMG6,TPCN2,ICAM5,CABIN1,NPL,AMACR,TRPC1,CA14,TUBB2A,TUBB1,SLC30A3,SLC30A4,TUBA1A,SLC17A7" Drug CID000736366 alpha-naphthylthiourea Stitch 4.44E-03 1.00E+00 2.41E-02 2.75E-01 23 84 "ADORA1,ADORA2A,ADORA3,APOC1,ATP2A2,BLM,DMPK,SLC25A18,ABI1,EDN1,DMTN,FCGRT,CELF1,GRIN2C,PTPN5,HP,HPR,ITGAM,PRODH,FUZ,SLC14A1,TF,TLR4" Drug CID000139622 difluoroboron Stitch 4.44E-03 1.00E+00 2.41E-02 2.75E-01 23 84 "BMPR1B,CACNA1A,MYEF2,EYA1,FGFR1,FGFR3,FOXG1,AGAP2,FOXM1,DBF4,HNF4G,MID1,MYH6,NKX2-2,NNAT,PMP22,PBRM1,ROBO1,ROBO2,RYR1,ACSBG1,UBTF,ZIC2" Drug 4692_DN Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADRA1D,SEMA6A,BIN1,MARK4,ATM,CFLAR,MTMR3,SLC4A7,ABI3BP,EDRF1,BRINP1,SMG7,DRD1,DTNA,MRNIP,PLEKHO1,FYB1,GFER,GLS,GRM8,KPNA5,NEUROD1,NFYA,RETREG1,PPARA,PTN,RAB3A,RPS6KA2,SH3BP2,PPP4R3A,MAPKBP1,SNCA,SOX2,ZCCHC24,MAPK8IP3,SEMA4A,TCF7,THRA,CABIN1,TRIO,KCNK12,XRCC4,DNALI1,EVI5,KCNAB1" Drug 5313_UP Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ASPHD1,APOC1,APP,MARK4,ATM,CFLAR,ST3GAL5,BTRC,TBRG4,UBE2L6,QKI,CSF1R,GIT2,RABGAP1L,ACOT8,CELSR3,NCALD,FECH,BAIAP2,FHL1,FOXG1,RUNDC3A,MSL3,POLL,GNAO1,NUDT21,PCLO,LIG4,LYRM9,NF1,KCNK10,LRP12,RALGDS,SHANK2,SLC20A2,LIMCH1,THSD1,INKA2,TBL1X,DAAM2,TRIO,UBE2H,LMF1,MPPE1,ST7" Drug 4412_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MRTFA,APBA2,APC,ATM,CFLAR,HAP1,FOXN3,RCHY1,RIMS2,SPOCK2,SUGP2,PLEKHO1,VPS13B,ERCC2,FGF13,FGFR1,ERAP1,SEPT9,RASSF8,ATXN2L,TJAP1,KIT,TM6SF1,SETD4,PPP2R2B,MAPK7,MAPK8,FAM120C,ZNF821,SMARCC2,RBM34,EMC1,KDM4C,ZBTB43,SEMA4A,MCF2L,PSD3,TMOD1,HIRA,VIPR2,KCNK12,SPHK2,EMSY,SLC17A7,KAT6A" Drug 3571_DN (-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "SLC12A5,ALCAM,PKP4,APC,GAS7,CDK10,ARRB1,ASPH,CFLAR,OSGIN2,CA12,CAMK2G,B4GALT6,CLCN3,SULT4A1,AKAP7,ABI3BP,ENTPD4,SH2B1,HDAC4,DBT,RABGAP1L,EGFR,MRNIP,NCALD,NR3C1,SERPINE2,MAPK8,SLC25A36,NEK11,ANKRD6,SLC6A8,SLC20A2,IQCE,TCF7,TCF7L2,SIK3,TK2,CDK20,VGF,MICAL1,LMF1,KLC2,SYNC,EMSY" Drug 6868_DN PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NDRG2,SEMA6A,ADAM15,CFLAR,CACNA1D,SPAG9,KYAT1,CHRNB2,WHRN,PDE4DIP,RASSF2,TBC1D5,DAPK3,FCF1,EML1,DCTN4,KIAA1109,FGFR1,RAB30,GPD2,NR3C1,HNMT,HSF2,BRINP3,ITPKB,KHK,LIG4,MBNL1,CNOT4,NUMA1,OCRL,SERPINE2,SLC25A23,PPP5C,MAPK8,GSTCD,RAB3GAP1,SPTAN1,TROVE2,NXT2,PSD3,PIK3R5,RBFOX2,SSBP2,VAV2" Drug 7239_DN Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ALCAM,PPFIA3,CDC14B,ATM,CFLAR,SCARB1,VAX2,ARHGEF6,ABCG1,LRIG1,DBN1,MFAP3L,TOM1,FEM1B,SIDT2,PHF20L1,FGFR1,FOXG1,FAM49B,ATXN2L,DHX35,IL6ST,INPP5B,IPO5,MAP4,MAPT,PDE3B,LRP12,TMEM104,PTPN13,CEP97,SBF1,ABLIM3,SMTN,BTBD7,SOX3,ZSWIM8,KDM4C,ITPRID2,KAZN,MCF2L,EXOC7,WSCD1,ZMYND8,NUP214" Drug 2359_DN Tolbutamide [64-77-7]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "APC,GAS7,APP,ASPH,EIF4G3,CAPN3,SPAG9,CLCN3,TPP1,QKI,NIPBL,IQCK,CHD1L,FRY,RABEPK,ANKMY1,PDLIM5,HBS1L,GART,SPIN1,IFI16,INPP5B,KLC1,N6AMT1,NF1,PDE3B,LRP12,RAB3A,RAD51D,ATG16L1,UEVLD,FBXO11,KBTBD4,COA1,ZHX3,SS18,MAPK8IP3,AHCYL2,PARD3,HIRA,ZNF24,ZNF32,PDSS2,SMIM8,NLRP3" Drug 2230_DN Ursolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ASIC1,ARID1A,C1QTNF3,LTBP4,BIN1,APBA2,ARRB1,MARK4,MTMR3,HAP1,CNOT8,TAOK2,SH2B1,CNNM1,EFNB3,BAIAP2,CAMSAP1,PDLIM5,DISC1,GLYR1,POLL,GPER1,CNTRL,GRIK5,GSN,HNMT,ITPKB,JAK2,STMN1,MAP4,TM6SF1,ADAM22,PALM,PTHLH,TCP11L1,SBF1,FBXO11,SNCA,EMC1,KDM4C,ELOVL4,SEMA4A,RPGRIP1L,PSD3,TNS2" Drug 4644_DN Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ACLY,ADCY6,MTUS1,APP,CDK13,SLC4A4,MYRF,SPAG9,CNOT8,QKI,HOMER3,WHRN,VCAN,TBC1D5,DBN1,SMG7,G3BP2,EXOG,RCAN1,FCF1,FAM13A,MBNL2,EPB41L1,ETV1,SORBS1,GLRB,SHISAL1,INPP5B,MPP2,OCRL,FA2H,TMEM231,RAB5B,RPS6KA2,ZFP30,FBXO11,EMC1,TAB2,SS18,TK2,TSC2,SSBP2,EVI5,SMIM8,PHTF2" Drug 1660_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ASPHD1,ASPH,CFLAR,HOMER3,AKAP6,ARMCX2,RBM12,EGR3,SORBS3,STX2,TUBB4A,RAB30,GLS,GRB10,GRIK5,MAP4K5,JAK2,KCNMA1,MDM4,MIA2,NFYA,NOS1,CNOT4,PDPK1,STRN3,RELN,FAM120C,RET,EMID1,WLS,SYBU,SLC20A2,SLN,ZCCHC24,TBL1X,TRIM2,ZNF34,TK2,CADM1,VLDLR,ZIC1,SPHK2,REEP1,SEMA3B,NAV2" Drug 1267_DN Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ABR,ANK2,APP,CDK13,NCOA1,SCAPER,MAP7,SOCS6,PLAA,RHOBTB1,DTNA,EZH1,RACK1,FGFR1,PRKAG2,GLS,LILRA2,SLC2A6,ICA1,ARHGAP12,MEF2C,NF1,NRGN,NUCB1,OGDH,OGG1,TRIM68,UEVLD,SHMT2,VAMP1,ATP11A,TBL1X,TCF4,TCF7L2,SLC44A1,KAT6B,TP53BP1,RBFOX2,TRPS1,ZKSCAN5,LAT2,ZNF142,LAMP5,PRDM2,NLRP3" Drug 7144_UP Ramipril [87333-19-5]; Up 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "BRAP,CRLF1,ZFYVE9,TPP1,HAPLN1,CNTNAP2,CTNND2,FAM131B,RUSC2,SMG7,CDON,AASS,ETV1,ZNF589,EFCAB2,ERAP1,C1QL1,GUCY1A1,GUCY1B1,KLF12,INPP5B,JAK2,LSS,PALM,PPARA,PEX5,FAT4,GTDC1,RGS10,ZNF671,MAPK12,ATXN7,SMARCD3,VAMP1,PDLIM2,WSCD1,DNAH7,CABIN1,HIRA,UGT8,MICAL1,WIPF1,LAT2,EMSY,KCNAB1" Drug 5024_UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MRTFA,TRMT9B,ANK3,GAS7,CDC14B,MARK4,ASPH,ADAM23,SCAPER,GYG2,GREB1,RUSC2,DMPK,EDN1,EGR3,EZH1,TBR1,GRM8,IL1RAPL1,SHISAL1,JAK2,KCNJ5,MBD1,MEF2C,NF1,NPR2,MTRF1L,LRRN3,PRKAR1B,ZDHHC14,TCP11L1,EMID1,ASAP3,SYBU,COA1,KDM4B,KAZN,TBCEL,SMG6,TCF7,TNS1,LAT2,KCNK12,SEMA3B,SLC17A7" Drug 7493_DN ST021200; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ABR,ADRA1D,APC,ARRB1,ASPH,BRINP2,ADAM15,ADGRB2,ST3GAL5,MTMR2,CHRNA4,HOMER3,CSF1,VCAN,CNTNAP2,TBC1D5,RIMS3,DBT,SORBS3,IRAK4,LRRC23,ZNF589,FHL1,ANKFY1,SHISAL1,TJAP1,JAK2,MAPT,MIA2,NFYA,PFKFB2,PLEC,MINDY2,PPP5C,RAD51D,TCP11L1,TMEM156,BTBD7,ZNF667,SPTB,RBFOX2,SSBP2,VAV2,ZNF45,UPF3A" Drug 4820_DN Gabazine [105538-73-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "SLC12A5,MTUS1,PPFIA3,CDK10,CASK,NUMB,ADAM15,SYNJ2,CNOT8,RAB28,NIPBL,ARMC8,PDE4DIP,USP6NL,TBC1D5,KIAA0753,LYPD1,PARD6A,GART,MSL3,FERMT2,BTN2A1,RNFT2,HNMT,MBNL1,NRCAM,PLEC,SYTL2,PTCH1,RAD51D,FERMT1,SLC20A2,PDZRN3,ERC1,ITPRID2,SYT1,FBXW11,BEX4,TPD52,UBTF,LMF1,NSD2,CLDND1,SH3GLB2,FTSJ1" Drug 3408_DN Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "EPB41L5,CDK5R1,STOML1,VAX2,SLC4A7,ABCG1,SIPA1L1,FBXL5,EXOG,DTNA,SUGP2,EIF5,POLR1B,FAM49B,CSPG5,ZNF44,SRCAP,PRRC2B,GRB10,NR3C1,KCNF1,ZNF862,NRGN,OGDH,OPA1,PRPH,TMEM104,RGS10,RNASEL,CCDC25,SBF1,ARFGAP1,RCOR3,MAPKBP1,PDZRN3,EMC1,TROVE2,POGZ,SS18,TNS2,ATP13A2,CABIN1,HIRA,NDRG4,HPS4" Drug 3050_DN Crotamiton [483-63-6]; Down 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "RALGAPA1,ARID1A,BCAR3,APBB2,FAM131A,DNAH17,MARK4,HIP1R,RAB33A,STOML1,SLC4A7,EXOG,MBNL2,ELAVL3,DLC1,PDLIM5,WASF3,POLL,GPM6B,GSN,PADI2,MAP4,MEF2C,MYO6,GPR85,SLC25A23,WDR25,PTCH1,RBBP6,RGS10,NEK11,ZNF821,RASA3,FAM214B,SNCA,ZCCHC24,SPTAN1,ATP10B,KCTD2,TRPS1,PLPPR2,ZBTB38,ZNF225,KCNAB1,KAT6A" Drug 2863_DN Dirithromycin [62013-04-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "SEMA6A,APC,ASPH,SLC4A4,ARHGEF1,DCAF4,NOS1AP,KIAA0513,DMPK,TSPAN5,EDNRA,SORBS3,ING4,FAM198B,FGFR1,CAMSAP1,FHL1,TDRKH,HSD17B1,TJAP1,INPP1,MAP4,MMP16,MPP2,GIT1,ADAM22,NPR2,OGDH,MAPK8,ELOVL2,RAD52,ROM1,SBF1,ZNF821,BCAN,PPP4R3A,ELOVL4,KIAA1107,PCDHA5,SIK3,BHLHB9,TPD52,PLPPR2,KLC2,NUP214" Drug 1303_DN Arecoline hydrobromide [300-08-3]; Down 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NDRG2,BRAP,ARNTL,STX16,FOXN3,CNOT8,NIPBL,HOMER3,PREPL,C2CD2,PPP1R16B,CTH,HP1BP3,DTNA,FEM1B,EPB41L2,PCYOX1,GLUL,LILRB4,EML4,HSF2,INPP5B,KIF2A,MBNL1,ZFYVE21,MINDY2,GTDC1,UEVLD,SLC2A5,CCDC88A,KIF1B,SRPK2,SS18,NXT2,SYPL1,TLR4,TMPO,RBFOX2,TPD52,NR2C2,TSN,NSD2,CLDND1,REEP1,MPPE1" Drug 2096_UP "Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADGRF5,APBB1,GAS7,APP,ASPH,SLC4A4,CFLAR,BTRC,CACNG1,CDH8,LARGE1,B4GALT6,ARHGAP22,RAB33A,DNAJB5,SDC3,SIDT2,MBNL2,EN2,PLEKHO1,DLL3,SPIN1,INPP5B,KIF5C,NF1,CNOT4,NRCAM,MINDY2,MAPK8,PRPH,TMEM231,PLEKHB2,ATXN7,ANKRD6,SLC20A2,ARHGAP26,ZBTB43,SPART,WSCD1,RPGRIP1L,UGT8,WNK1,MAP3K12,KCNAB1,SENP7" Drug 838_UP 5248896; Up 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ASIC1,PDE8B,ASPH,ST3GAL5,OSGIN2,ARHGEF1,SCARB1,ADGRG1,NMT2,AKAP7,SIPA1L1,ARHGEF4,GIT2,DBT,ATN1,DSCAM,DTNA,MAMLD1,CNNM1,EIF5,EFCAB2,TRMO,POLL,DIDO1,GRM8,GSN,HNMT,LIG4,LYRM9,SETD4,RAB3IL1,RGS12,TRAPPC13,FNDC3A,SLC22A4,ZKSCAN3,SPART,PLCB1,AHCYL2,ZNF34,TK2,REEP1,EPM2A,ST7,SSPN" Drug 4740_DN Sulfamerazine [127-79-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "AK2,GAS7,BCAS1,ARHGDIG,ASPH,ALDH4A1,SLC4A4,CBFA2T2,ARHGAP33,SOCS6,PLEKHB1,QKI,HOMER3,SLC4A8,CRY2,SDC3,RIMS2,TBC1D5,JAKMIP2,EFNA3,MBNL2,HSD17B14,DLC1,AFF2,GALC,GLYR1,TDRKH,KITLG,RETREG1,LRP12,SAMD9,ZSCAN32,CEP97,RGS10,RGS12,PREX2,PEX26,ZKSCAN3,VAMP1,PLCB1,SEMA4A,KIAA0930,CABIN1,HIRA,LMF1" Drug 3663_DN Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ABHD6,ACTN1,NDRG3,ADRA1D,MRTFA,PKP4,APBB1,APBB2,APC,APOC1,ASPH,CCNT1,CHD1L,DAPK3,SLC12A6,RCAN1,FEM1B,SIDT2,MBNL2,ERCC2,WAC,TRAF3IP2,GART,CACFD1,ELOVL5,MBNL1,NF1,NFYA,SERPINI1,RAD51D,ENOX1,KIRREL1,IL17RB,ELMO2,TMCC1,EMC1,SPTAN1,EXOC7,FBXW11,TRIM2,TMPO,LMF1,NSD2,DPF3,RNF146" Drug 3328_DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ALCAM,PPFIA3,CDK10,PLA2G4C,ATM,ADAM15,CFLAR,SYNJ2,BTRC,CA4,SPAG9,VAX2,CRY2,CTH,CTNND2,TM9SF4,DBT,SMG7,MRNIP,STX2,VPS26C,RRAGB,ANKFY1,B4GALNT1,ZNF276,RAB30,PRRC2B,CACFD1,ELOVL5,LSS,NUMA1,OCRL,PLCD1,SLC25A23,PMS2,PRKAR1B,PRODH,RPS6KA2,WDTC1,CDK19,CEP68,PLCB1,TMPO,VGF,REEP1" Drug 6878_UP "H-89, Dihydrochloride; Up 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ABAT,ASPHD1,ATP6V0A1,QKI,CRMP1,CSNK1E,DOCK4,DBT,DTNA,PLEKHO1,VPS26C,ZNF589,PDLIM5,GART,MAP4K5,MUM1,C2orf72,KCNN1,KIF5C,ADAM22,CNOT4,PALM,PIK3R1,PPP2R2B,PPP3CC,GON4L,RAD52,RGS10,GSTCD,RPS6KA2,CLIP1,ZNF821,SLC6A8,SIRT2,SMARCD3,LIMCH1,CLASP2,CLSTN2,SS18,ELOVL4,ARHGEF9,TMOD1,TMPO,MICAL1,NUP214" Drug 6650_DN Amoxapine [14028-44-5]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NME5,PLA2G6,AMPD3,APAF1,ALDH4A1,NRP2,FOXN3,CLCN4,PICK1,CSNK1E,DBT,EXOG,CELSR3,EFEMP1,FAM49B,FYN,DENND2A,SEPT9,ZNF276,GPM6B,LPAR4,GUCY1B1,KLF12,IL6ST,VWA5A,MEF2C,MSRA,NUCB1,ODF2,TTLL7,SEC61A2,PPP4R3A,TNIK,KDM4C,UNC5B,SPTAN1,NXT2,TBCEL,PSD3,TIAM1,PLPPR2,VGF,KLC2,EMSY,SEMA3B" Drug 5758_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ACTN1,AP2A2,NME5,BIN1,CDC14B,CDK10,CLCN4,HAPLN1,VCAN,SLITRK5,EDRF1,HDAC4,DAPK3,MFAP3L,KBTBD11,CDON,COQ7,EPHA5,FER,OGA,B4GALNT1,SRCAP,GHR,MSL3,NR3C1,IL12A,L1CAM,ZNF862,NDP,NPR2,RETREG1,SYTL2,PTHLH,RAB3IL1,FAM184A,GAL3ST4,SUGCT,FBXO11,FAM214B,SLC14A1,PHLDB1,DNAH7,TK2,CABIN1,NAV3" Drug 6448_UP Estrone [53-16-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "SYN3,ABHD6,ADORA1,NLGN4X,CAMK2B,NEURL1,QKI,AKAP7,WHRN,TENM4,ARHGEF10,PDE4DIP,PHF14,HDAC9,ARMCX2,RUSC2,ATN1,SGK2,EGR3,EPHB1,ZNF589,HPCAL4,ANKFY1,ERAP1,TMEM8B,HLF,KCNMA1,MAPT,AFF1,MMP16,CNOT4,LRP12,PRKAR1B,FAM120C,SH3BP2,SLA,PKNOX2,ZHX3,HECW1,PEG10,INKA2,PLCB1,POPDC3,TRIM2,NSD2" Drug 2460_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADRA1D,KIDINS220,AP2A2,MTUS1,AMH,PDXK,CASK,CADM3,SCAPER,CACNA1A,CAMK2B,NMT2,ABCG1,VCAN,EFNB3,PLEKHA1,TNK2,FGFR1,CAMSAP1,GABRA2,GRM1,NCKAP1L,TJAP1,IL6ST,LSS,MAP4,MEF2C,MYO7A,NF1,NUMA1,ST8SIA5,PPP5C,MAPK7,CNTLN,RAD52,ZCWPW1,ZNF493,EMID1,SEC14L1,ANKRD6,SLC1A7,DOK5,FCHO1,KAZN,SLC44A1" Drug 3864_DN Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "CDC42BPA,APP,ARRB1,ATP6V0A1,SPAG9,ENTPD6,ZMYM4,SRSF11,SOCS6,TAOK2,NMT2,HOMER3,BAG4,LRIG1,GPRASP1,ARHGAP32,DAPK3,DTNA,EIF4G1,ZNF589,GLYR1,GLS,KCNK1,MIA2,NFYA,PCDH9,SSH1,RETREG2,GTDC1,GSTCD,RXRA,AP1AR,WDTC1,KDM4C,SPTAN1,ZBTB43,VPS13A,ASTN2,TBL1X,AP4E1,TRIO,TRPC1,NAV2,SNX27,PHTF2" Drug 1223_DN nordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADCY6,PLA2G6,C1QTNF1,APAF1,RGS20,SYNJ2,CCNT1,FOXN3,CSNK1E,RUSC2,LYPD1,DNM2,SIDT2,SORBS3,DMTN,POMT1,TRAF3IP2,DISC1,MAP4,MEF2C,NUMA1,ODF2,SLC25A23,CDIP1,MBOAT7,CNNM2,ZSCAN32,RIPOR1,RALGDS,RPS6KA2,SH3BP2,SH3GL2,PEX26,EPN2,SMARCC2,SNCA,SPTAN1,STX1A,WWC1,TCF4,KIAA0930,TCF7L2,ZNF34,UBTF,UBE3B" Drug 6729_DN Erythromycin [114-07-8]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "RALGAPA1,BIN1,ATP1A3,SEPT7,NMT2,STOML1,HOMER3,CSNK1E,VCAN,SPOCK3,PLEKHO1,DMTN,ETV1,EFEMP1,IQCG,B4GALNT1,ERAP1,INPP5K,GLRB,MSL3,GRM1,HNMT,IL6ST,LIG4,TAGLN3,WDR25,PTN,RALGDS,KIRREL1,FOXRED2,MAPK12,SCN8A,FBXO11,TMCC1,ARHGAP26,SPTAN1,MAPK8IP3,KIAA1107,DOCK9,HIRA,DNAJC12,WIPF1,WNT7A,ZNF711,NT5M" Drug 1549_UP Clotrimazole [23593-75-1]; Up 200; 11.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADCY2,ANK2,APAF1,STX16,CARS,ARHGAP33,CTH,CTIF,GSDME,DYNC1I1,ANKRD46,ZNF589,KIAA1109,TMEM164,EVL,GABRG2,NEU3,PCDH17,DIDO1,FICD,KCND3,KCNH2,MX1,MYT1,NEFH,PDE1C,GPSM2,CDIP1,MBOAT7,CNNM2,RAB3IL1,CEP97,RAD52,RNASE1,RNASEL,ZNF671,ASAP3,R3HDM2,SLC1A7,GLT8D1,ZC3H13,MLST8,TPM1,TRPM2,PRDM2" Drug 3181_UP Ethacrynic acid [58-54-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ACTN2,AMPD3,ARHGDIG,RGS20,DDX3Y,N4BP2L1,MTMR3,CLDN10,NMT2,STOML1,CREM,CSF1R,NCALD,ANKMY1,ACSL4,PDLIM5,GPM6B,PCLO,HLF,KCNB1,KCND1,KCNJ4,KCNMA1,AFF1,ZNF862,SLCO1C1,NTRK3,OLR1,OPRL1,TREM2,PIK3CD,POU3F2,PTAFR,PPP1R9A,RPH3A,ZNF423,PLCB1,TBCEL,TCF4,TK2,DAAM2,PIK3R5,MKRN3,TFIP11,AP3B2" Drug 6234_UP Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADCY6,ADRA1B,SRPX,PPFIA3,PLA2G4C,BCL7A,MTMR3,BTRC,RCBTB2,ZFYVE9,PLAA,IFFO1,DMPK,TOM1,ING4,ZNF589,C1orf61,KHDRBS3,OGA,GLS,GRB10,BTN2A1,IGSF1,INPP5B,LMO2,VWA5A,MPP2,ZNF862,MYT1,NF1,NOS1,PDE1C,SERPINE2,RALGDS,NEK11,NUBPL,SLC15A2,BTBD7,KDM4B,POGZ,SEMA4A,CRTC1,TRPM2,UBE3B,GAN" Drug 4660_DN Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MTUS1,CDK5R1,SCAPER,CANX,SOCS6,CLU,IQCK,CREM,CREB5,ARHGEF10,CTNND2,ZFYVE16,DNAJC6,KIAA0753,DLG3,RGS17,SORBS1,ATP2C1,ZNF44,SEPT9,ARFIP1,NUDT21,SCIN,KIF2A,MEIS1,GIT1,NF1,CNOT4,STRN3,PMS2,SAMD9,CNTLN,MSANTD2,RGS10,ZNF671,TRAPPC13,SCG5,FRMPD1,KBTBD4,LIMCH1,ARHGAP26,MAPK8IP3,CRTC1,UBE3B,PHTF2" Drug 3246_UP Lactobionic acid [96-82-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MTUS1,C1QTNF3,RGS20,SYNJ1,TAOK2,SIPA1L1,MFAP3L,DTNA,FCF1,PLEKHA1,RRAGB,FGR,CAMSAP1,IQCG,STON1,EML4,BTN2A1,IPO5,VWA5A,TM6SF1,MIA2,KITLG,NF1,NOS1,SLC11A2,CEP41,CNNM2,TCP11L1,ZNF365,RBM34,TSNAXIP1,TROVE2,NXT2,ELOVL4,ARHGEF9,CAMSAP2,ZNF34,TMOD1,TMPO,BEX4,ZBTB14,ZNF24,PLSCR4,PHTF2,SSPN" Drug 6967_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NDRG2,MRTFA,CNTNAP1,SEMA4G,KIF1A,NEURL1,TCEAL2,CSF1R,EDRF1,MED12,DPP6,DRD1,EFNA3,VPS13B,ZNF589,GPR153,OGA,GLS,MSL3,INPP5B,KCNH1,KIF5C,MITF,PFKFB3,PLTP,PPP5C,PRPH,NKAIN1,ZCWPW1,GTDC1,MYH14,PAQR6,SUPT20H,ZKSCAN3,IFT122,POPDC3,TK2,CDK20,TRPC1,FAM155A,LAT2,REEP1,ITM2C,RNF170,SSPN" Drug 6266_DN Butamben [94-25-7]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ARID1A,APBB2,ALDH4A1,BTRC,PLAA,CHD1L,GIT2,SMG7,DNM2,DSCAM,DTNA,ING4,FHL1,ANKFY1,DPYSL4,GRB10,BTN2A1,CLASRP,IGSF1,INPP5B,MITF,MPP2,NRGN,PDPK1,PPP2R2B,GON4L,PEX5,RAB3IL1,RALGDS,TCP11L1,BTBD7,SMARCA4,WDTC1,SOX3,ZBTB43,ELOVL4,TACC1,EXOC7,IQCE,CRTC1,KCTD2,METTL3,VAV2,VGF,ZNF248" Drug 4614_DN Colchicine [64-86-8]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MTUS1,BIN1,APAF1,APC,SCAPER,MAP7,NMT2,ABCG2,RAB26,CTNND2,KLHL3,EGFR,EN2,RRAGB,ST3GAL6,BAIAP2,SEMA4D,ANKFY1,USP21,CAMKK2,ZNF276,GNAS,GRIK2,HAS2,MAPT,MX1,NASP,NDP,PRKAR1B,SAMD9,WDR25,PTHLH,RIPOR1,RALGDS,CCDC25,MCMBP,FOXRED2,SAFB,SUPT20H,SLC20A2,LIMCH1,PLCB1,THRA,HEY1,ZBTB14" Drug 5213_DN LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "APC,APP,SCAPER,AP4M1,MAGI1,PLEKHB1,CNOT8,SLIT2,QKI,TBC1D5,DSCAM,DTNA,MAMLD1,FEM1B,SUGP2,EGFR,SORBS3,ING4,ENO2,FGFR1,IQCG,MALT1,GPM6B,ELOVL5,HNMT,KCNH2,NPR2,SLC11A2,NUMA1,PLEC,RAD52,CCDC25,ROM1,NEK11,TRA2B,WDTC1,ZBTB43,ASTN2,RPGRIP1L,TNS2,DICER1,CHST8,TRIO,MAP3K12,HPS4" Drug 7264_DN Clorsulon [60200-06-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "AK2,BIN1,NCOA1,ATM,MPDZ,CFLAR,MTMR3,HIP1R,PPP6R2,ZNF337,DBT,PARD6A,TNK2,EPB41L1,STX2,F8,FGFR1,FOXM1,PDLIM5,FAM49B,ZNF44,TRAF3IP2,GART,SESN1,ITPKB,MAPT,NPR2,CCSER2,MAPK3,SNRK,FAM102A,KBTBD4,CDK5RAP2,IFT122,FCHO1,RGL1,PHLDB1,EXOC7,KIAA0930,TCF7,TNS2,BHLHB9,TSC2,OSBP2,WIPF2" Drug 6234_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NCOA1,MTMR9,KRIT1,SOCS6,RAB28,SLC4A7,CHD1L,ABCG1,SIPA1L1,SOCS5,ARHGAP32,DCAF8,LYPD1,MED12,TSPAN5,RBM12,SCML2,FGFR3,PDLIM5,ATP2C1,MAP4,MITF,MMP16,NCAM2,NFYA,PMP22,PTPN13,RAB3IL1,RIC8B,DCUN1D2,MYH14,FOXRED2,ANKRD6,PEX26,ARFGAP1,PDZRN3,SP2,LHPP,CAMSAP2,TCF7L2,CLASP1,ZNF106,UBE3A,WIPF2,C12orf4" Drug 3732_DN PNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "PLA2G6,APP,ATP1A3,SLC4A4,CAMK2B,LARGE1,CLCN4,AKAP7,IQCK,CRMP1,VCAN,PDE4DIP,ARHGAP24,AK5,HIPK3,ING4,FGFR1,SEPT9,GCNT2,RAB30,POLL,PSRC1,GRIK2,GRIK5,GUCY1B1,INPP5B,KCNJ5,MAPT,MDM4,NEK1,NPR2,MAPK8,PEX5,ROM1,SOX15,DDN,COLGALT2,MAPK8IP3,IQCE,TCF4,SZT2,PSD3,CHST8,CADM1,SEMA3B" Drug 7432_DN Fenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "APC,ASPH,NCOA1,ARHGEF1,TAOK2,HOMER3,SIPA1L1,PDE4DIP,GNE,DTNA,SORBS3,EIF5,STX2,GLS,GPD2,SLC2A6,MAPT,MITF,MMP16,NAP1L1,NEK1,NUCB1,PDE3B,RETREG1,SLC25A23,PLXNB1,PMP22,PRKAR1B,RALGDS,SAFB,MAPK12,ITSN1,FERMT1,PPP4R3A,EPN2,LHPP,ELOVL4,STX1A,KANK1,NSD1,NPL,LMF1,NSD2,REEP1,ST7" Drug 1053_DN prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "CDC7,AK2,OGT,MAP4K3,ARRB2,STX16,ATP6V0A1,MTMR2,ZMYM4,RAB28,PLAA,CHD1L,DCAF8,DNM1,NR1D2,EFEMP1,OLFM1,TMEM164,SMC2,HBS1L,GHR,BRINP3,JAK2,KCNJ3,MMP16,NFYA,NLE1,CYBC1,MSANTD2,UBR7,ROBO1,ATXN7,SFPQ,SMTN,SON,EMC1,POGZ,SS18,FAM168A,FBXW11,KAT6B,UBTF,PRDM2,SMIM8,PHTF2" Drug 2278_DN Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NDRG3,CDC42BPA,KCNAB2,GAS7,FAM131A,ARRB1,PLA2G4C,DNAH17,ALDH7A1,CADM3,RIPK1,CFLAR,SYNJ2,ARHGEF7,SCAPER,KRIT1,RCBTB2,AKAP7,ABI3BP,GREB1,RIMS2,DLG3,PLXNC1,FHL1,SEMA4D,MSL3,JAK2,KCNH2,MAP4,MYT1,PDPK1,MINDY2,PRKAR1B,PEX5,TMEM231,KLHDC8A,BCAN,PEX26,PPP4R3A,WDTC1,PLCB1,KAZN,PCDHA6,SYNC,NUP214" Drug 2578_DN Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADRA1D,BIN1,ARRB1,SLC4A4,ADAM23,CACNA1I,REPS2,TAOK2,FAM149A,ENTPD4,CDON,DNM2,MTSS1L,DLC1,ATP8A1,FCGRT,FYB1,ZNF44,GAD2,GNG3,NCKAP1L,SMAD1,MEF2C,SCAMP5,MID1,NOS1,NTRK2,PMP22,MAPK7,LRRC49,PTCH1,FAM184A,FAM102A,CNKSR2,RGL1,CRTC1,ATP13A2,SLC44A1,KCTD2,TPM3,LMF1,CLIP2,STMN4,FAM13C,ST7" Drug 632_DN "novobiocin sodium, USP; Down 200; 100uM; SKMEL5; HG-U133A" Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "MTUS1,ALAD,BCAR3,APAF1,CDK13,EIF4G3,NRP2,ARHGAP33,ENTPD4,RUBCN,MATR3,HP1BP3,SGK2,EFNB3,FAM13A,B3GAT1,PRRC2B,GSN,CELF3,MAN1B1,AGFG1,MAP4,MBP,NUMA1,GPSM2,POLG,PPP3CA,PKN2,MAPK7,GON4L,RBBP6,CLIP1,SFPQ,SLC11A1,TNIK,SOX10,EMC1,SRPK2,NACC2,PARD3,TPM1,TRIO,TSN,KLC2,ST7" Drug 4368_UP Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ADORA3,PLA2G6,ALK,CDC42BPA,CAMK2B,USP2,ARHGEF2,CDH8,SLC22A6,CLTB,COL9A3,NOS1AP,CTIF,SRGAP3,DUSP9,SGK2,FHL1,NSG1,FYB1,STMN2,KCNH2,KCNJ5,MAN2A2,MGAT3,TAGLN3,PCBP3,PDE2A,PRKCB,RGS4,TTLL7,KCNIP1,S100B,SLC2A5,SORCS3,RIMS1,ZC3H13,ABCC8,SYN2,RPGRIP1L,TRO,HIRA,UCHL1,LAT2,ZNF225,JPH3" Drug 2663_DN haloperidol; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "NDRG3,MRTFA,DOC2A,MPDZ,HIP1R,SLITRK5,PPP1R16B,EDRF1,DAPK3,CTIF,CDON,TOM1,DYRK1A,ERBB2,KIAA1109,ZNF44,ERAP1,SEPT9,ALDH1L1,RUNDC3A,ZNF276,MAPT,MYO6,PLCB2,PMP22,PPARA,MAPK7,RIPOR1,RAB3IL1,RAD52,KHDRBS2,RXRA,SCN2B,FAM102A,AMBRA1,NLGN1,FAM214B,SOX2,ARHGAP26,TROVE2,MAPK8IP3,EXOC7,TRIO,LMF1,PCBP4" Drug 1015_UP genistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "PKP4,DDO,FAM131A,CA4,CACNA2D1,WHRN,LRIG1,FAM169A,DNM2,RCAN1,EGR3,IRAK4,POLL,GPM6B,SPACA9,GUCY1A2,ATXN2L,TJAP1,KCNH2,MATK,LYRM9,ZNF862,PPP2R2B,PTPRE,RAD52,RALGDS,GTDC1,RGS3,RGS10,RGS12,TCP11L1,PKNOX2,MAPKBP1,ZCCHC24,THSD1,TTBK2,VAMP1,POPDC3,RPGRIP1L,TIAM1,R3HDM1,CABIN1,VAV1,VGF,VLDLR" Drug 4799_UP Zalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ATM,ATP6V0A1,SYNJ1,MTMR2,BTRC,KRIT1,QKI,CHD1L,ARHGEF10,PUM1,ABI1,EIF4G2,IRAK4,ACSL4,PRKAG2,NCKAP1,GPM6B,IL6ST,KCNJ3,KCNN1,KCNN2,VWA5A,MBNL1,MMP16,NDUFA5,NNAT,NUMA1,STRN3,CPEB3,PPP4R3A,WDR47,UHRF1BP1L,NXT2,NEK4,PLCB1,TRIM2,TPD52,SSBP2,DNAJC12,CLDND1,ZNF184,EMSY,SCG2,ST7,RNF146" Drug 4396_DN Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "ARID1A,BIN1,APLP1,SLC4A4,CDK5R1,CA4,NEURL1,CDC42,LHX2,ZFYVE9,SLC4A7,C2CD2,CSF1R,DZIP3,BAIAP2,FOXG1,PDLIM5,TPK1,MPP6,GAB1,GAD1,DISC1,NR3C1,KCNN1,TM6SF1,NASP,ODF2,SERPINE2,MAPK8,GRAMD1C,PTHLH,CEP97,TCP11L1,SEC14L1,ZHX3,IQSEC2,PHLDB1,SMG6,WSCD1,DICER1,HIRA,ZIC3,EMSY,KAT6A,SSPN" Drug 2358_DN Flutamide [13311-84-7]; Down 200; 14.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.44E-03 1.00E+00 2.41E-02 2.75E-01 45 195 "AMPD3,MAP4K3,CDK13,SLC4A4,EIF4G3,MTMR2,SOCS6,FADS2,FEZ1,DCTN1,SGSM2,DNM2,DPH1,DTNA,VPS26C,FGFR1,FYB1,ERAP1,MAP4,NEK1,NFYA,RETREG1,RC3H2,PTPA,MAPK3,SAMD9,RAB3IL1,RAB5B,ZDHHC14,BSDC1,AMBRA1,FBXO11,DZIP1,CCDC88A,SLC12A2,NCDN,FBXW11,AHCYL2,TK2,RBFOX2,PLPPR2,VIPR2,XRCC4,REEP1,ACTR3B" Drug 4637_UP Perphenazine [58-39-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "ADGRF5,SPARCL1,FAM135A,KCNAB2,FUBP1,ARHGEF2,STOML1,CLTB,AKAP7,CTH,AK5,EIF5,ETV1,EZH1,CORO2B,ZNF589,FYB1,SRCAP,GNAL,GNG4,GRM8,SOX21,GUCY1A2,ICA1,MMP16,OGG1,CLDN11,PDE2A,RETREG1,NLE1,PTPRH,RGS4,NEK11,FAM102A,SLA,PKNOX2,ARHGAP26,SYT1,COBL,SYT5,TRIO,SSBP2,VIPR2,PHTF2" Drug 5080_DN Lobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "MTUS1,NME5,EP400,ALDH4A1,ALDH7A1,SCAPER,SPAG9,CDC42,FOXN3,TPP1,CPS1,CNTNAP2,KIAA0753,PARD6A,AK5,EDIL3,EFNA3,FAM13A,SPEG,ZNF589,CINP,B4GALNT1,ERAP1,GOLGB1,GPER1,INPP5B,CNOT4,PDE4A,PIK3R1,PPP2R5C,CNNM2,ZSCAN32,RPS6KA2,SBF1,CSRNP3,SCN8A,SCG5,FBXO11,SMARCD3,LIMCH1,ASTN2,ARHGEF12,GPR161,TFIP11" Drug 1168_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "MAP4K4,NCOR1,CSF1R,CSNK1G3,VCAN,ZNF337,ZEB2,C2CD2L,RHOBTB1,DNM2,FRY,F3,CAMSAP1,FYB1,TXNL4A,GPR22,LPAR4,ELOVL5,ITGA7,TM6SF1,ENPP2,GPR85,LRP12,PMS2,PRKCZ,DEF8,GON4L,RALGDS,RET,LGR4,MAPK12,FERMT1,WDTC1,SP2,COLGALT2,KANK1,FAM168A,TCF4,TCF7L2,AHCYL2,KAT6B,TNS1,XRCC4,HPS4" Drug 5614_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "NDRG2,NME5,APC,ARHGEF2,RCBTB2,NECTIN3,CRY2,PDE4DIP,SDC3,GIT2,JAKMIP2,HP1BP3,SMG7,TSPAN5,SUGP2,MBNL2,STX2,NCALD,FAM49B,GART,GCNT2,HTATSF1,GNG3,NR3C1,INPP5B,LSS,TM6SF1,EPN1,PRKAR1B,PRPH,RGS3,FERMT1,FBXO11,EPN2,KDM4C,TROVE2,ST5,PLCB1,TRIM2,HIRA,FAM155A,SF1,ZNF711,SLC17A7" Drug 4385_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "ADCY6,AMT,KCNAB2,SLC2A11,CDK5R1,GYG2,QKI,AKAP7,SLC4A7,HDAC4,SMG7,DTNA,EDNRA,SIDT2,OPTN,EGR3,KAT8,DPYSL4,TPK1,GPR153,GPR37,CNTRL,NR3C1,KCNJ3,IPO5,MAP4,KITLG,ADAM22,CNOT4,NUMA1,PDE3B,PIK3R1,PPP2R2B,PKIA,SYTL2,WLS,PHLDB1,MCF2L,FAM208A,TCF7L2,PCDHA6,TMPO,HIRA,UBTF" Drug 2143_UP Gramine [87-52-5]; Up 200; 23uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "ASIC1,NDRG2,MTUS1,CDC42BPA,GAS7,APP,FUBP1,HAP1,CLCN4,NMT2,COL9A3,CREM,PDE4DIP,EDRF1,GPRASP1,RIPOR2,DAPK3,TMCC2,ST8SIA3,EEF1A2,MBNL2,LPAR6,KIAA1109,FGFR1,CAMSAP1,PRELID3A,SRCAP,PADI2,KLF12,CD200,NUMA1,P2RY1,PDE4A,ZCWPW1,TMCC1,TNIK,ZC3H13,EPB41L3,SEPT8,SLC44A1,FAM155A,VAV2,SPHK2,SLC17A7" Drug 3060_DN Digoxigenin [1672-46-4]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "CDC7,ST3GAL5,MAP7,CBR1,CLCN3,SEC31B,OSBPL3,SLITRK5,RHOBTB1,KBTBD11,RBM12,PLEKHO1,ZNF589,CAMSAP1,GLUL,INPP1,ITGAM,NEK1,ST8SIA5,PLEC,RETREG2,PTAFR,PTCH1,ZSCAN32,RAD51D,ZC3H14,TCP11L1,SUPT20H,ST6GAL1,PAAF1,ARHGEF40,SS18,SEPT8,CEP68,ARHGEF9,VPS13A,PJA1,CAMSAP2,ATMIN,RBFOX2,UBTF,MARCH8,ZNF248,NETO2" Drug 223_UP TTNPB; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "ADARB2,BIN1,APAF1,CADM3,CACNA2D1,CAMK2A,CH25H,KRIT1,CD86,B4GALT6,IFFO1,CREM,PDE4DIP,DGKG,SGK2,EFNB3,EPHB1,CDKL3,F3,TMEM8B,SRCAP,RUNDC3A,LILRA2,KLF12,ADAM22,OGG1,PFKFB2,PNMA3,CEP41,MAPK8,PTPRH,RAD52,ZCWPW1,TCP11L1,FNDC3A,IFT122,ZCCHC24,ZNF423,KAZN,WSCD1,TRIM2,SEZ6L,VIPR2,TRIM9" Drug 1172_DN 15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "GRAMD1B,ADRB2,AK2,MICAL2,VCAN,PPP1R16B,KBTBD11,NR1D2,RBM12,EPB41L2,RASGRP2,ZNF589,CAMKK2,CGREF1,PSRC1,IRF8,MAN2A2,MEF2C,N6AMT1,NME4,NUMA1,OGG1,PDE4A,KCTD15,PLCB2,TNPO2,MINDY2,PTCH1,LGR4,FERMT1,ARHGEF40,KANK1,GSE1,MLC1,IQCE,KIAA0930,THBS4,CABIN1,HIRA,MICAL1,LAMP5,HPS4,NAV3,ZNF248" Drug 2525_DN Strophanthidin [66-28-4]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "MARK4,NCOA1,ST3GAL5,SYNJ2,CAMK2G,EPS15L1,RHOBTB1,KBTBD11,ABI2,MRNIP,PLEKHO1,F8,ZNF589,CAMSAP1,GLUL,IFI16,KIF2A,SETD4,PDCD2,PDE3B,RETREG2,PPP5C,PTCH1,ZFP30,ST6GAL1,PAAF1,ARHGEF40,CLASP2,ZNF302,CEP68,KANK1,FAM208A,ATMIN,ARHGEF12,TK2,TNS1,TPM1,METTL3,TST,UBTF,FLRT2,ZNF32,REEP1,ZNF248" Drug 5084_DN Resveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.55E-03 1.00E+00 2.47E-02 2.81E-01 44 190 "ADRA1D,APBB2,APC,CDK10,FUBP1,RAB28,CLCN3,HAPLN1,VCAN,EDRF1,DTNA,EFNA3,ETV1,ANKMY1,SCML2,SEMA4D,TRAF3IP2,GAD1,GNAS,PSRC1,SCIN,MAPT,TM6SF1,MID1,NF1,MED1,SAMD9,PEX5,PID1,SUGCT,CCDC88A,SNCA,ZNF415,WWC1,TCF4,TMPO,CABIN1,TRIO,FAM155A,OSBP2,XRCC4,PHTF2,TIGD6,SENP7" Drug ctd:C023035 "3,4,5,3',4'-pentachlorobiphenyl" CTD 4.56E-03 1.00E+00 2.47E-02 2.81E-01 227 1231 "SERPINA3,SLC25A25,ADD3,AXIN2,FZD9,ADORA2A,ADRA1B,ADRB2,ALAD,SPARCL1,SEMA6A,ALCAM,SRPX,ARHGAP20,AMPH,LRFN1,GPAM,PHYHD1,SHROOM2,CDC14B,ARNTL,CADPS,CDK13,ASGR1,RASL11B,ATP1B3,BARD1,BBS2,RGS9,NRP2,SYNJ2,C1QC,IL33,CA8,CACNB2,CBR1,CCK,MTMR7,CDH2,DCLK1,LRRFIP1,CRLF1,ADGRG1,CHN2,NMT2,CLTB,CNTFR,COL4A5,AKAP5,CNRIP1,CP,CREM,AKAP12,GDA,ABCG1,CTNND1,FAM131B,CYBB,BRINP1,LYPD1,ARNT2,DLG4,DMD,DNM1,CDON,DTNB,DUSP9,ABCC5,TSPAN5,EDN1,SGK2,SYT15,OPTN,PLEKHO1,EPB41L1,RCAN2,MRPL37,F3,FAM198B,PTK2B,CHST15,FGF1,FGF13,CAP2,FOXO3,FLT1,ATP2C1,ST6GALNAC3,FYN,PHYHIPL,GAD2,B4GALNT1,MYOZ2,GCK,GCNT2,GFRA1,GHR,PPARGC1A,TXNL4A,RAB30,GPD2,GPM6B,STON1,NR3C1,GSTM5,GSTT2,GUCY1A1,ELOVL5,ACOT7,SYNPO,HMGCR,HSD17B1,IGF1,IGFBP1,DOCK7,IL11RA,DIPK1A,ITGA7,KCND3,KCNH2,KCNJ5,KCNK1,KHK,LIFR,LSS,SMAD9,MAOB,MDFI,MGAT3,KITLG,SCAMP5,CD200,CCDC80,MSR1,MX1,NCAM1,SFR1,NEFH,NFIA,NFE2L2,NFIX,NPTX1,NRGN,NTRK2,GPR88,PALM,PC,PCSK5,PDE3B,PDE4B,ENPP2,PIK3R1,RETREG1,PKM,PLCL1,FXYD1,PMP22,PSAT1,SEPT4,POLG,PPARA,MED1,PPP2R2B,PPP2R5E,MAPK3,PRPH,MASP1,APTX,SNRK,PXK,PTN,PTPRD,PTPRN,PTPRZ1,RAB3IL1,RALGDS,SUGCT,TMEM100,RTN1,SCN4B,SCP2,SMPD3,IL17RB,GALNT10,HSPA4L,SCG5,ITSN1,SHMT2,HKDC1,ST6GAL1,SLC1A3,SLC2A5,FAM214B,ARHGEF40,SLC14A1,CPEB4,PDZRN3,KDM4B,PDZD2,SPP1,LHPP,SST,APOM,JMJD6,TACC1,PDLIM2,TBCEL,EHBP1,CUX2,TJP1,ICAM5,TLR4,TMOD1,TPM1,NPL,TST,TUB,CADM1,CLDND1,SLC13A3,LGI4,ATP6V0E2,NDRG4,STOX2,PLSCR4,CAMK1G,PIANP" Drug ctd:C017906 3-dinitrobenzene CTD 4.56E-03 1.00E+00 2.47E-02 2.81E-01 81 390 "ABAT,KIDINS220,HACE1,USP35,USP28,APAF1,AQP4,SPTBN4,MARCH3,BRINP2,RASL11B,ATP2B2,NOL4,ATP6V0A1,CFLAR,METTL6,CERS5,CDH2,JAM2,FAM189A2,TJP2,SUMF2,NECTIN3,CPS1,PDE4DIP,SLC45A1,TBC1D5,CPEB2,SLC12A6,RCAN1,EDN1,GPR61,LRRC23,GMPR2,F8,UBE2E3,DPYSL4,SORBS1,STAMBP,CYP46A1,RND1,FERMT2,SPACA9,GSN,PSIP1,ATG4C,USP54,IL6R,KCND1,MAN2A2,SHC3,PCDH8,PCSK1,PDYN,CDK14,ABCB1,SKOR1,MAPK3,USP47,RFX4,KCNIP1,FERMT1,CCDC88A,SNAP25,PALLD,FNBP1,STXBP1,OBSL1,TEK,SLC44A1,TIAM1,DDHD1,TPM1,TUBB2A,UCHL1,SLC13A3,MICU3,SH3GLB2,SCG2,CIAPIN1,GOPC" Drug CID000005022 phenylisopropyladenosine Stitch 4.57E-03 1.00E+00 2.48E-02 2.82E-01 20 70 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ALDH7A1,LRBA,CHRM1,GPR162,KCNA6,MAT2A,PDE3B,PDE4B,PDE4D,PRKACB,RNH1,RPE" Drug 7207_UP Benzethonium chloride [121-54-0]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.65E-03 1.00E+00 2.52E-02 2.87E-01 43 185 "ADRA1D,AMPD3,APBA2,CADM3,ST3GAL5,SCAPER,CA4,CALB2,ARHGEF2,SOCS6,CHN2,BAG4,HAPLN1,CNTNAP2,EDNRA,EGR3,CORO2B,KIAA1109,FGF12,C1orf61,GAD1,SRCAP,TDRKH,HNMT,INPP5B,KCNMA1,KCNN1,MITF,ADAM22,SLC11A2,PHKG1,PPP5C,RFX2,RGS12,SLC6A9,KIF21B,SPART,ABCC8,POPDC3,TCF4,TRIM2,THBS4,JPH3" Drug 5439_DN Pyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.65E-03 1.00E+00 2.52E-02 2.87E-01 43 185 "ABR,BLM,SCAPER,SRSF11,LHX2,NECTIN3,AKAP12,CTNND2,EDRF1,DCAF8,SMG7,RABGAP1L,RBM12,SUGP2,KAT8,FGFR3,SYNCRIP,AHDC1,GHR,KCNMB4,PSRC1,GPR19,RNFT2,MUM1,BRINP3,PLXNB1,ELOVL2,NKAIN1,RET,RGS3,NEK11,ITSN1,FBXO11,EPN2,SMTN,SLC20A2,MAPK8IP3,KANK1,JMJD6,TCF7L2,AHCYL2,ZMYND8,UBTF" Drug 4688_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.65E-03 1.00E+00 2.52E-02 2.87E-01 43 185 "MRTFA,DOC2A,APBA2,MARK4,ATM,CA12,ARHGEF2,QKI,GREB1,RHOBTB1,DSCAM,EDNRA,RASGRP1,EGR3,PLEKHO1,EPB41L1,COQ7,LRRC23,FGFR1,SYNCRIP,GAD1,INPP5K,MSL3,IGSF1,JAK2,ADAM22,NEUROD1,PIK3R1,RETREG1,SMOX,LRP12,PTPRE,RAB3IL1,RAD51D,SGK1,ARC,IQCE,HIRA,VGF,VLDLR,XRCC4,NDRG4,REEP1" Drug 5364_DN Anisomycin [22862-76-6]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.65E-03 1.00E+00 2.52E-02 2.87E-01 43 185 "MTUS1,PDXK,FOXN3,SACS,PARD6A,DPYSL2,MAMLD1,TBC1D16,RACK1,CAMSAP1,TRAF3IP2,RNFT2,BRINP3,KHK,MAPT,MATN2,MMP16,THYN1,NRCAM,PBX1,PCDH9,PDCD2,PIK3R1,SNX10,PMP22,RALGDS,MAP6D1,LGR4,SUPT20H,TEX2,RAP1GAP2,MPRIP,KANK1,KAZN,ZMAT3,ZNF106,METTL3,ZMYND8,ZBTB14,REEP1,SLC38A1,MVB12B,ZNF248" Drug CID000005732 zolpidem Stitch 4.69E-03 1.00E+00 2.54E-02 2.89E-01 14 43 "AFF2,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,SLC6A1,SLC6A11,ZEB1,TST" Drug CID000396644 AC1L9CY0 Stitch 4.69E-03 1.00E+00 2.54E-02 2.89E-01 14 43 "TUBD1,ERBB2,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MAP4,MX1,ABCB1,TUBB2A,TUBB1,TUBA1A,EPM2A" Drug CID000150911 "1,3-DCG" Stitch 4.69E-03 1.00E+00 2.54E-02 2.89E-01 25 94 "ABHD6,ADCY5,ADCY6,ADCY8,DGKZ,DGKD,CALM1,RGN,DGKI,NSL1,DGKB,DGKG,RASL12,NCF2,NPR2,P2RY1,PRKCB,PRKCG,PKN2,PRKCZ,SLC6A7,TRPC1,TRPC3,PLPPR5,PLD4" Drug CID000003485 glutaraldehyde Stitch 4.69E-03 1.00E+00 2.54E-02 2.89E-01 25 94 "ABHD6,API5,PDXK,CAPN3,CHM,BOC,ELN,ERCC2,PIPOX,F8,TAOK3,PNMA2,TBR1,GAA,NEU3,MAG,MATK,MEST,MID1,APTX,MARCH1,ASRGL1,ADHFE1,NEU4,TMPO" Drug CID000040391 pinazepam Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "DYNLL1,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000416151 AC1L9B1Q Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "TKTL1,RASL12,TPK1,OGDH,SLC1A2,SLC1A3,SLC6A11" Drug CID009604626 [(E)-ethylideneamino]thiourea Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "CCK,IP6K2,KITLG,NDUFA5,SHANK2,RGL1,DNMBP" Drug ctd:C035976 "2,4,2',4'-tetrachlorobiphenyl" CTD 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "CHRNA4,CHRNB2,GABRA1,GABRG2,NR3C1,MAPK3,MAPK8" Drug CID000061974 EDDA Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "PDXK,CCKBR,RGN,SCAMP5,OXTR,SST,TF" Drug CID000472326 9-butoxynonanoic acid Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "CREM,AFF2,GFAP,MAG,MBP,MOG,PLP1" Drug ctd:C095427 A 86929 CTD 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "ADORA1,ADRB2,CCKBR,DRD1,EDNRA,EDNRB,PTAFR" Drug CID000127872 ACEA-1011 Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "GLRB,GRIK1,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D" Drug CID003033860 loprazolam Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "TOX,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000071257 girisopam Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HTR2A" Drug CID000072104 premazepam Stitch 4.72E-03 1.00E+00 2.55E-02 2.91E-01 7 15 "ZMYND10,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug 2859_DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.75E-03 1.00E+00 2.56E-02 2.91E-01 42 180 "CDC7,CDC42BPA,PPFIA3,EIF4G3,BTRC,KRIT1,CDC27,ZMYM4,CLOCK,FAM169A,ZFYVE16,TBC1D5,KIAA0586,FBXL5,LYPD1,IRAK4,FGFR3,OGA,GHR,MALT1,KIF2A,MAP4,ADAM22,PDE3B,STRN3,HSPA4L,ITSN1,PPP4R3A,SMTN,UHRF1BP1L,ERBIN,VPS13A,TACC1,ANKRD12,FAM208A,TCF7L2,WASHC4,ACTR6,UBE3A,C12orf4,PHTF2,IFT88" Drug 6886_DN "trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 4.75E-03 1.00E+00 2.56E-02 2.91E-01 42 180 "ARID1A,CDC7,BCAR3,APP,BCL7A,CFLAR,ARHGEF1,SOCS6,RCHY1,FAM169A,HDAC9,KIAA0753,DYRK1A,KMT5B,USP21,STAG2,DENND2A,DIDO1,HAS2,DHX35,IFI16,SMAD1,NACA,STRN3,MED1,RGS3,CLIP1,DHX30,CAND2,ZNF302,ERBIN,ST5,ZC3H4,NACC2,KAT6B,TRPM2,ZMYND8,ZNF189,PRDM10,CIAPIN1,MVB12B,ZNF248" Drug 7356_UP Zuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.75E-03 1.00E+00 2.56E-02 2.91E-01 42 180 "KIDINS220,ANK3,APC,ARHGDIG,PDE8B,ST3GAL5,ADGRG1,FAM189A2,PDE4DIP,FAM169A,KBTBD11,DSCAM,EDNRA,EGFR,EIF4G2,ERCC2,EZH1,TPPP3,SRCAP,RND1,RASSF8,ATXN2L,HMGCR,HSF2,IL6R,KCNMA1,LMO2,CNOT4,LRP12,ZSCAN32,C1orf54,KHDRBS2,ATXN1,ZNF821,SYBU,SNCA,TROVE2,TRIM2,RPGRIP1L,R3HDM1,CABIN1,DNAJC12" Drug 5306_UP Propofol [2078-54-8]; Up 200; 22.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.75E-03 1.00E+00 2.56E-02 2.91E-01 42 180 "OGT,PPFIA3,PLA2G4C,ATM,CFLAR,ST3GAL5,C5,CACNA1D,UBE2L6,TAOK2,QKI,NECTIN3,FEZ1,ARHGEF4,DCAF8,SMG7,DTNA,SORBS3,ZNF589,GPR153,ALDH1L1,RND1,GLYR1,PCLO,HNMT,KCNN1,KIF5C,LSS,MAP4,NOS1,PILRA,SYBU,PPP4R3A,SMTN,ZHX3,FCHO1,STX1A,ANKRD28,TRIM2,WIPF1,ZNF24,SEMA3B" Drug CID000159861 gracillin Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ABCG2,KITLG,ABCB1" Drug CID006449940 HxA3-C Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CACNA2D1,GSTCD,TAC1" Drug CID000131948 WS009A Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug DB01412 Theobromine Drug Bank 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ADORA1,ADORA2A,PDE4B" Drug CID000128344 julifloricine Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,CACNA2D1" Drug ctd:D002800 Cholinesterase Inhibitors CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,APP,BCHE" Drug CID000013564 bromoethyl acetate Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "BOC,F3,SYNE1" Drug CID000008293 cythioate Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,TMEM132D" Drug CID000037829 dichlormid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "OGT,HMGB1,SAFB" Drug CID000011875 2-nitrobenzoyl chloride Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug ctd:C006649 methylatropine CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,TRH" Drug CID000006909 trichloroisocyanuric acid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "DBI,DNER,GSTCD" Drug CID000637429 Calebin-A Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ABCB1,MAPK9,MAPK10" Drug CID000443039 isoimide Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "PTPN5,HP,HPR" Drug CID000130363 4-amino-5-fluoropentanoic acid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ABAT,GAD1,GAD2" Drug CID000061948 MDBGN Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "SIRPA,PDCD2,ABCC8" Drug CID000065956 KC8851 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "KCNA2,KCNA4,KCNH2" Drug CID000191927 S-ethyl-CoA Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACLY,CS,PC" Drug ctd:C110041 "9-chloro-2-(2-furyl)-5-phenylacetylamino(1,2,4)triazolo(1,5-c)quinazoline" CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ADORA1,ADORA2A,ADORA3" Drug CID000026761 E106E Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000073811 NSC 90 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000193328 Dimba Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,CEP170,DNER" Drug CID000129710 FG 8205 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CCKBR,STX2,RUSC1" Drug CID005311351 Pd164333 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID011193251 flubendiamide Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ZMYND10,RYR1,RYR3" Drug CID000192562 AC1Q6A5A Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "FOXM1,B3GAT1,TACR1" Drug CID014758064 "pyrido[3,4-d]pyrimidine" Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EGFR,ERBB2,ERBB4" Drug CID000076727 TL 401 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CNR1,BOC,FOXM1" Drug ctd:C021604 CL 218872 CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "GABRA1,GABRB3,GABRG2" Drug CID000129003 S-312-d Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "APLP1,CACNA2D1,CABIN1" Drug CID000055919 pelrinone Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ALDH7A1,PDE3A,PDE3B" Drug CID009571042 RU 47213 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,CHRM1" Drug CID000004478 AC1L1I9D Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,ABHD6,BCHE" Drug CID000433934 NSC-339901 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CP,PIK3C2A,RNH1" Drug CID000024375 ZnBr2 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ARX,SYNE1,ARHGAP9" Drug ctd:C013571 inositol pentaphosphate CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "IP6K1,IP6K2,IP6K3" Drug CID000007735 CHDM Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "DST,TSC1,TSC2" Drug CID000012092 4-(dimethylamino)benzoic acid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "DMTN,F8,OPA1" Drug CID003083646 piperidine phosphate Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,APP,BCHE" Drug CID009543058 "2,4-dihydroxylamino-6-nitrotoluene" Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "DYNLL1,RDX,TNNT1" Drug CID000067793 ethyl trifluoroacetoacetate Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "SEMA6A,EDNRA,F3" Drug CID000010043 AC1Q2A5Z Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CHL1,L1CAM,NCAM2" Drug CID000136915 N-phenyliminodiacetic acid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CSF2RA,F8,SALL1" Drug CID000034058 gallium citrate Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CIT,TF,SMUG1" Drug CID000065768 tryptamide Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "MAT2A,SIRT2,SIRT1" Drug CID000010408 phytone Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "GAA,KCNH1,PKM" Drug ctd:C415840 ZD 2574 CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug ctd:C063380 9-((2-phosphonylmethoxy)ethyl)guanine CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "SLC22A6,ABCG2,ABCB1" Drug ctd:D000443 Alcuronium CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CHRM4,CHRNA4,CHRNB2" Drug CID005274625 myriceric acid C Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID000065719 geneserine Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,APP,BCHE" Drug DB08299 "4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid" Drug Bank 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "PDE4A,PDE4B,PDE4D" Drug DB00425 Zolpidem Drug Bank 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "GABRA1,GABRA2,GABRA3" Drug CID000017072 isononanol Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "SEMA6A,INA,POLK" Drug ctd:C118218 LY 379268 CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "NR3C1,GRM2,GRM3" Drug CID000177370 CAM 4515 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "B3GAT1,TAC1,TACR1" Drug CID000110765 (-)-Physovenine Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,APP,BCHE" Drug DB01223 Aminophylline Drug Bank 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ADORA1,ADORA3,PDE3A" Drug CID003082265 Boc-cck-8 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CCK,BOC,PENK" Drug CID000099116 voachalotine Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,F3" Drug CID000132919 "Wy-44,221" Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "AGT,TAC1,TAC3" Drug CID011018843 "pyrrolo[1,2-a]pyrazine" Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "CCKBR,GRM5,SST" Drug ctd:C027172 isospaglumic acid CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "FOLH1,GRM2,GRM3" Drug CID003035933 Dctfpg Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "KYAT1,GGT7,GGT5" Drug CID000024585 isopulegol Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "BCHE,STX2,KAT8" Drug CID000036332 2-ethylacetanilide Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "EDN1,EDNRA,EDNRB" Drug CID005487388 WIN 62582 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ALDH7A1,PDE3A,PDE3B" Drug CID005748335 PLPGH Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "PDXK,GAD1,GAD2" Drug CID000342465 benzothiazol-2-ylacetonitrile Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "MAPK8,MAPK9,MAPK10" Drug CID000030364 4-methyldibenzothiophene Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "KDM5D,DBT,DNER" Drug CID000005965 BC48 Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "ACHE,BCHE,DTNB" Drug ctd:C024829 8-hydroxyguanine CTD 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "MT3,OGG1,WRN" Drug CID001795542 S)-2-amino-2-methyl-4-phosphonobutanoic acid Stitch 4.77E-03 1.00E+00 2.56E-02 2.91E-01 3 3 "GRM5,GRM8,MAP4" Drug CID000004101 methenamine silver Stitch 4.78E-03 1.00E+00 2.57E-02 2.92E-01 46 201 "SERPINA3,FMNL2,FZD9,BCAR3,MYH7B,APLP1,APOC1,BCHE,CAPN3,RUNX1T1,FMNL3,CDC42,NOG,CX3CR1,SRGAP3,ABI1,CELSR3,CD320,FER,ACTL6B,RND1,TCERG1,HNMT,NKD1,AFDN,SERPINE2,ANLN,PRKCZ,MAPK8,MAPK9,RDX,RTKN,CLIP1,ANKRD6,WDTC1,FNBP1,SYP,ALG1,ARHGEF12,ACTR6,DAAM2,TTPA,ZIC1,SPIRE1,VANGL2,NETO1" Drug CID000003100 diphenhydramine Stitch 4.82E-03 1.00E+00 2.58E-02 2.94E-01 21 75 "ASIC1,ATM,ASIC3,CHRM1,AASS,HRH3,HNMT,KCNJ4,PDCD2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TAC1,TAC3,TACR1,AZIN2,NTSR2,HPS4" Drug ctd:D015122 6-Mercaptopurine CTD 4.82E-03 1.00E+00 2.59E-02 2.94E-01 58 265 "PCDH19,AGT,SORCS2,KCNT1,AMPD3,PI16,SLC7A14,CHRD,BARD1,CA4,CDC25B,CLGN,JAM2,AKAP12,PHACTR3,ZEB2,HEPH,MFAP3L,TMCC2,CHRDL1,ERBB2,EFEMP1,FCGR3A,CAP2,AKAP3,DLL3,GATM,GDF9,HPGDS,KCNMB4,SLC35G1,KCNQ2,ASPRV1,MEST,SCAMP5,MT3,MYH6,NASP,IGSF11,ENPP2,PENK,PACSIN1,TMEM100,S100B,SATB1,SCG5,MYO16,EPB41L3,ABCC8,TAC3,THBS4,TRH,VAV1,VGF,VIPR2,TSPAN11,ZIC3,ZBTB16" Drug CID000446537 C-cluster Stitch 4.84E-03 1.00E+00 2.60E-02 2.95E-01 34 139 "LGR5,DST,INA,COL4A5,ABCG1,CSF1,CSF3R,CSNK1E,PITPNM3,DCTN1,DPP6,ATN1,LRRC23,DCTN2,GFAP,IL6R,JAK1,KCNMA1,KIF5A,MAP2,KITLG,NEFM,NEFH,NF1,PLEC,PTPA,PRPH,PSMA6,RPE,FBXO11,DDN,ZNF346,TUBA1A,GAN" Drug CID005288160 etheno-NAD Stitch 4.85E-03 1.00E+00 2.60E-02 2.96E-01 27 104 "ACLY,AGT,APBB1,APBB2,ATP1A2,ATP1A3,WASF1,CDC42,HOMER3,CTNND1,ABI1,NRN1,ACTL6B,BAIAP2,FYB1,NCKAP1,FERMT2,GPT2,EXOSC10,RELN,TROVE2,DNMBP,ACTR6,TRIO,VAV1,WIPF1,WIPF2" Drug CID000002720 thiazide Stitch 4.85E-03 1.00E+00 2.60E-02 2.96E-01 27 104 "ADD1,SLC12A5,APOC2,SLC4A4,CA4,CA8,CA12,CACNA2D1,CALB1,CBFA2T2,TAOK2,DCT,SLC12A6,HP,HPR,KCNK3,KCNMA1,MID1,NPPA,SLC12A2,SLC12A4,SLC20A2,CA14,TSC1,WNK1,WNK3,WNK2" Drug CID000000239 beta-alanine Stitch 4.85E-03 1.00E+00 2.60E-02 2.96E-01 27 104 "ABAT,ALDH7A1,CPS1,LRIG1,BOC,EARS2,MED12,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD1,GAD2,GLRB,CNDP1,GRIK1,CIT,OGDH,APTX,SCN2A,SLC6A1,SLC6A11,TAC1,TAC3,KAT6B" Drug 1057_UP "radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 4.85E-03 1.00E+00 2.60E-02 2.96E-01 41 175 "OSBPL1A,CDC42BPA,MADD,CAMK2G,CLU,NMT2,ARMC8,GIT2,DBT,RCAN1,DTNA,DNAJB6,CAP2,NOP56,ATP2C1,FYN,STAG2,NCKAP1,DIDO1,MUM1,HSF2,KCNK1,NAP1L2,NFYA,STRN3,MBOAT7,MED1,KLK6,MORC4,ATXN1,HSPA4L,SGK1,SH3BGR,PPM1E,JMJD6,SYT1,TBL1X,UBE3A,LMF1,ZNF189,FXR1" Drug ctd:D003630 Daunorubicin CTD 4.86E-03 1.00E+00 2.61E-02 2.96E-01 49 217 "ACHE,ANK2,ATM,ATP1A2,KIF1A,BARD1,BCHE,BID,CACNA1G,PRC1,CBR1,MYOM2,CACNA2D2,NGEF,ABCG2,COX4I1,CYBB,DMD,E2F5,EDN1,EDNRA,EDNRB,F3,CAB39,LUZP2,NR3C1,IGF1,IL6R,JAK2,KCNH2,LSAMP,MAPT,MDM4,TAGLN3,MYH6,MYH7,NCF2,NPPA,ABCB1,PIK3R1,PPARA,PRKCZ,PYGM,RBBP6,SCN2B,SMPD3,ZMAT3,TLR4,TNNT1" Drug CID000004422 nalmefene HCl Stitch 4.86E-03 1.00E+00 2.61E-02 2.97E-01 16 52 "EDN1,EDN3,EDNRA,EDNRB,ELN,NELFCD,GFRA1,MITF,NNAT,OPRL1,ENPP2,PDYN,PENK,RET,SOX10,TRH" Drug CID000003053 diethylenetriaminepentaacetic acid Stitch 4.86E-03 1.00E+00 2.61E-02 2.97E-01 16 52 "CCK,CCKBR,ARHGAP32,CASP8AP2,EGFR,RASL12,DLL3,GNAS,MCHR1,NACA,KCNIP1,SST,SSTR1,SSTR2,TF,KAT6B" Drug CID005311181 iloprost Stitch 4.88E-03 1.00E+00 2.61E-02 2.97E-01 33 134 "ADCY2,ADCY5,ADCY6,ADCY8,ADORA2A,ADRB2,AGT,ARRB1,ALDH7A1,CACNA2D1,LRBA,CLU,EDN1,EDN3,EDNRA,EDNRB,F3,FER,HPGDS,GNAS,LILRA2,NUDT21,HAS2,PTGDR2,TNFAIP8L3,NOS1,PIK3C2A,PRKACB,SELL,ABCC8,HHIP,TNFRSF1B,TTPA" Drug 366_UP Gleevec; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "RBM10,ALAD,GAS7,BCAS1,ARNTL,HIP1R,FADS2,AATK,B3GAT3,DMPK,DSCAM,SIDT2,CELSR3,MRNIP,RGS17,LRRC23,EFS,FGFR1,FAM49B,AHDC1,RNFT2,ARHGAP19,HNMT,ITPKB,L1CAM,NPPA,NRGN,PFKFB2,PMS2,MBOAT7,MAPK8,SBF1,SPATA7,EMC1,STX1A,COBL,AGTPBP1,TNS2,ATP13A2,THBS4,KCTD2,TRIO,NSD2,MPPE1,NUP214" Drug 5020_DN Bretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ARID1A,AK2,ALCAM,APBA2,ASPH,ATM,BCL2L2,CFLAR,BTRC,CACNA1D,SCARB1,RCBTB2,FOXN3,STOML1,RIMS2,RABGAP1L,EFNA3,PLEKHO1,FGF12,FAM49B,TPK1,INPP5K,HTATSF1,TJAP1,MAPT,GIT1,MSI1,PC,PRKAR1B,PTPRE,SLC1A7,SLN,TROVE2,POGZ,THSD1,ARHGEF9,KIAA0930,TCF7,TGFBR3,TK2,ZMYND8,FAM155A,VGF,VIPR2,GDPD5" Drug 960_DN 5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASPHD1,ADCY6,AMPD2,CDC42BPA,APP,NCOA1,MPDZ,REPS2,AKAP7,KIAA0586,SUGP2,EGR3,EML1,CGREF1,GHR,GPER1,RNFT2,MIA2,MMP16,MPP2,GIT1,ADAM22,MYO9A,SLC11A2,NRGN,PLEC,PLXNB1,PPP2R5C,WDR25,SEC61A2,MYH14,SYBU,ABLIM3,EPN2,SCMH1,LHPP,CLSTN2,DIP2A,EXOC7,AHCYL2,AP4E1,TPD52,TRIO,PCBP4,PHTF2" Drug 4833_UP 6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NME5,APBA2,ASPH,ADAM23,MTMR3,CA12,CACNB2,ARHGEF1,QKI,FAM149A,SLC4A7,ENTPD4,DCAF4,MAML1,CTIF,ARMCX2,SMG7,ATN1,MAMLD1,EDN1,EFNA3,EGR3,FGFR1,C1orf61,ICA1,JAK2,KCNJ3,KIF5C,MMP17,MPP2,MAPK8,GRAMD1C,RET,SGK1,SMTN,ARFGAP1,SMARCA4,KDM4C,CLSTN2,ARC,PDLIM2,DMXL2,CABIN1,PIK3R5,ZIC3" Drug 2907_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABAT,ARID1A,AMT,CDC42BPA,PPFIA4,CAPN3,ENTPD6,HOMER3,PPP1R16B,RUBCN,DAPK3,GIT2,B3GAT3,SGSM2,DTNA,ING4,COQ7,ERAP1,COPS8,PRRC2B,MUM1,ATXN2L,ITGAM,JAK2,IPO5,CDK14,CCSER2,MINDY2,PTPA,PTPRN2,PTX3,TMEM231,DGLUCY,PEX26,ARHGEF40,PALLD,KDM4C,ZBTB43,TSPYL2,TCF7,KCTD2,TNNT1,TPD52,NPDC1,PHTF2" Drug 7015_UP Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ARID1A,AMT,ALDH4A1,ALDH7A1,BACH1,BCL2L2,GYG2,SLIT2,PICK1,ABI3BP,SDC3,CTIF,BRINP1,ARMCX2,MFAP3L,ATN1,EFNB3,RASGRP2,NRN1,FGFR1,PRKAG2,FHL1,C1orf61,TXNL4A,GPD2,GRM1,INPP5B,KCND3,LSS,MAP4,NF1,PDE3B,MAPK8,RYR1,FBXO11,KIAA0930,TCF7L2,DOCK9,PCDHA5,AHCYL2,TMOD1,KCNK12,MAP3K12,KCNAB1,KAT6A" Drug 2943_UP Asiaticoside [16830-15-2]; Up 200; 4.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "KIDINS220,AP2A2,PLA2G6,MRTFA,NCOA1,CFLAR,CACNA1A,CACNB2,MAP7,SLC16A4,ZFYVE9,CLOCK,USP6NL,DBT,EDNRB,PHC2,CAMSAP1,PRELID3A,CSPG5,ALDH1L1,GLRB,STON1,ADAMTS13,ITGAM,KPNA5,MEF2C,AFDN,N6AMT1,NRCAM,CCSER2,CEP41,SAMD9,PTCH1,EMID1,RASA3,SPTAN1,DDN,TROVE2,CAMSAP2,PDLIM2,SIK3,SLC44A1,TNNT1,PRMT8,FLRT2" Drug 7480_DN Dimaprit dihydrochloride [23256-33-9]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "KIDINS220,OSBPL1A,AK2,BCAS1,APP,MARCH3,CAPRIN2,ATP6V0A1,CFLAR,MTMR2,C5,B4GALT6,ZFYVE9,NMT2,BAG4,CTH,RABGAP1L,EDNRA,EFNA3,LRRC23,ANKMY1,ATP2C1,SEPT9,GPD2,RASSF8,IDH3B,DIPK1A,KIF2A,MEIS2,ODF2,SMIM7,STRN3,FSD1,PPP3CC,GON4L,RGS10,MAPK12,FBXO11,EPN2,PLCB1,KAZN,HEY2,CABIN1,RBFOX2,SSPN" Drug 7269_UP Aceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,APC,SHROOM2,MARK4,SLC4A4,PICK1,ARMC8,NCOR2,ARHGEF10,CTNND2,LYPD1,SMG7,CDON,DMTF1,PLEKHO1,CDKL3,ATP8A1,B4GALNT1,COPS8,MSL3,SPACA9,GSN,GUCY1B1,DIPK1A,L1CAM,MMP16,NASP,NPR2,PALM,PLXNB1,TMEM231,RGS10,RXRA,FRMPD1,PPP4R3A,SMARCD3,MYH15,MAPK8IP3,ELOVL4,IQCE,TRPC3,WIPF1,PRDM2,NUP214,ADAMTSL3" Drug 419_DN chlorpromazine hydrochloride; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "EP400,AQP6,PDXK,PLEKHB1,SOCS5,KCTD3,TUBD1,STX2,ZNF589,FGFR3,SCARA3,SEC23B,STAG2,GAD2,DBF4,ADAMTS6,SCIN,KTN1,LAMP2,MARK3,MBD1,ADAM22,MYO6,SLC11A2,NLE1,STRN3,PPM1B,PRKCZ,RIPOR1,SEC61A2,SH3GL3,SLA,URGCP,ELMO2,FNBP1,NMNAT2,SPART,ATP10B,VPS13A,COBL,TCF7L2,WASHC4,VIPR2,ZNF195,MPPE1" Drug 4281_UP Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "C1QTNF3,PPFIA4,GAS7,MARK4,N4BP2L1,ADGRB2,ADGRB3,NRP2,KSR1,FUBP1,CACNA1I,NEURL1,TPP1,HOMER3,VCAN,PDE4DIP,CTNND2,CTIF,ABCC9,LRRC17,F5,IQGAP2,USP19,RUNDC3A,GPR17,GPR37,BTN2A1,MARK1,MOBP,ADAM22,NPTX1,PCBP3,PBX1,EPN1,ELOVL2,KCTD17,ZFP2,SLC4A3,KDM4B,DDN,ACSBG1,TAC3,AP4E1,TIMP4,ZNF24" Drug 2936_DN Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABAT,NDRG2,AP1B1,PLA2G6,ANK2,PPFIA4,MARK4,MTMR2,CBS,SOCS6,NMT2,HOMER3,AKAP7,CRY2,PDE4DIP,SLITRK5,DZIP3,EDRF1,SPATA2,LPAR6,CD320,TRMO,POMT1,ERAP1,DISC1,SRCAP,USP19,PADI2,ATXN2L,AGFG1,IDH3A,MEF2C,MIA2,NDUFA5,NF1,CNOT4,NUMA1,PDE4B,SBF1,NUBPL,ARHGEF40,EXOC7,TCF7L2,OBSL1,AP4E1" Drug 2383_DN Norethindrone [68-22-4]; Down 200; 13.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,APP,NCOA1,SCAPER,LDLRAD4,CAPN3,CAST,RAB28,CPS1,TRAPPC9,SORBS3,COQ7,ZNF589,ERAP1,SEPT9,ALDH1L1,COPS8,ELOVL5,TJAP1,INPP5B,ITGA7,KIF2A,KLC1,MAP4,MIA2,MYO9A,CNOT4,PDE4A,ZNF426,TRHDE,RAB3A,DCUN1D2,TCP11L1,RPS6KA2,SH3BP2,FBXO11,ZNF667,KIF1B,DDN,EXOC7,CAMSAP2,TCF7L2,KAT6B,RBFOX2,TPM1" Drug 2442_UP Calciferol [50-14-6]; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "SYN3,ATP6V0A1,CACNB4,CHM,CLCN3,CRMP1,VCAN,NCAN,KIAA0513,DCT,FCF1,EIF1,OLIG2,EFS,PIPOX,FHL1,ANKFY1,CAMKK2,LILRA2,ATXN2L,IL6R,AFF1,MYO6,NCAM2,PFKFB4,PGAM2,MTRF1L,SEPT4,MAPK8,MASP1,MYH14,FOXRED2,PEG10,SPTB,SEPT8,VPS13A,PLCB1,SYN2,WWC1,TGFBR3,TK2,LMF1,NSD2,XRCC4,ZNF225" Drug 5528_DN Sulindac [38194-50-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "C1QTNF3,APBB2,MPDZ,CFLAR,SCAPER,MAP7,TAOK2,VAX2,CREM,SH2B1,MICAL2,CTNND2,GIT2,DBT,OPTN,SORBS3,STX2,ANKMY1,FGFR1,TRAF3IP2,DISC1,GRB10,SPACA9,IL6ST,ITPKB,KCNJ3,KIF2A,KIF5C,LMO2,VWA5A,NEK1,PDE4A,TMEM231,CEP97,RAD52,BCAN,ZNF365,ZHX3,ELOVL4,DIP2A,COBL,POPDC3,TRIM2,CABIN1,HIRA" Drug 987_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "KIDINS220,PPFIA1,ALDH4A1,BMP7,CARS,KRIT1,SRSF11,NMT2,HOMER3,CREM,FEZ1,RUBCN,MFAP3L,DLG3,TRAPPC9,GNE,POLR1B,TRMO,CRCP,RNFT2,KCNJ3,MAP4,MDM4,NASP,SSH1,MED1,PRKACB,RAD51D,RALGDS,GTDC1,ROBO1,MAPK12,SEC14L1,ERC1,ZBTB43,ITPRID2,JMJD6,WWC1,TCF7L2,AHCYL2,KAT6B,RBFOX2,HIRA,UBE3A,LMF1" Drug 7357_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "APOC1,CDK13,MTMR2,ZMYM4,BAG4,SDC3,DCAF8,DBT,HP1BP3,LYPD1,DTNA,SORBS3,FGFR1,FHL1,GALC,COPS8,GLYR1,GPD2,DHX35,KCNH2,LIG4,MBD1,KITLG,STRN3,PPP5C,SYTL2,RALGDS,GSTCD,SAFB,FNDC3A,ZBTB43,ITPRID2,SS18,NXT2,TACC1,FBXW11,TCF7L2,SZT2,KCTD2,CABIN1,XRCC4,NDRG4,KCNAB1,UBE3B,ACTR3B" Drug 5345_UP Midecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "AP2A2,ANK3,SEMA7A,APOC1,ARRB2,BCL7A,ST3GAL5,SYNJ2,BAIAP3,QKI,DTNA,FEM1B,NCALD,F5,ZNF589,ZNF276,GLYR1,GRIK5,BTN2A1,TJAP1,INPP5B,KCNJ3,LIG4,LSS,MATK,MEIS1,RGS10,NEK11,TCP11L1,ITSN1,FNDC3A,SOX2,ZHX3,UNC5B,ZBTB43,PLCB1,PSD3,SLC44A1,TK2,UBE2H,NT5M,HPS4,KCNAB1,ST7,UBE3B" Drug 4288_UP PNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADD2,AMPH,PKP4,APAF1,GAS7,SPTBN4,PTCH2,CADM3,N4BP2L1,BMPR1B,CFAP410,CAMK2B,SYNGR3,SLC24A2,CSF1,MICAL2,DBT,NTM,NR1D2,RASGRP2,DLC1,PDLIM5,GPER1,RASSF8,ICA1,KIT,MAP2,MAP4,SLCO1C1,GDPD2,CCDC40,CCDC102B,SH3BP2,DZIP1,SLC1A2,ATP10B,SLC19A3,OBSL1,CBX5,TMPO,CHST5,ZMYND8,CADM1,SF1,MKRN3" Drug 2108_DN Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG3,AP1B1,CDC42BPA,PPFIA1,ATM,ATP2B1,MPDZ,CFLAR,MAP7,RCBTB2,NMT2,QKI,RUSC2,KLHL3,MBNL2,SORBS3,ELAVL2,VPS26C,ZNF589,FER,ZNF44,GAD1,EML4,KLF12,MAP4,SETD4,NLE1,PLCD1,LRP12,TNPO2,PTHLH,SEC14L1,SLC1A3,CCDC88A,SPATA7,SS18,SEPT8,WWC1,TBL1X,TCF4,SATB2,METTL3,HIRA,WNK1,MPPE1" Drug 4734_UP Flumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "APC,AZGP1,BAIAP3,CACNA2D1,CDH2,EPS15L1,TCEAL2,NCOR2,CYBB,RASSF2,RUSC2,HIPK3,SIDT2,EML1,EN2,IGSF6,REEP2,PTK2B,FHL1,GABRA2,NEU3,PCDH17,RUNDC3A,GNG3,FERMT2,CACFD1,GRM7,ICA1,TJAP1,KCNH2,GPR85,PLCD1,MAPK7,PTAFR,RAB3A,C1orf54,ASAP3,SLC2A5,KDM4B,WDTC1,DOCK9,TK2,TPM2,KCNK12,SYNC" Drug 2233_UP Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASIC1,APAF1,MARK4,ADGRB2,NRP2,CFLAR,BTRC,CAST,RHBDL1,ADGRG1,HOMER3,WHRN,CNIH3,NTM,TRAPPC9,ATN1,HIPK3,IRAK4,MTSS1L,ATP8A1,OLFM1,FHL1,CAMKK2,GABRA2,GAD1,GPR162,RND1,MSL3,GPM6A,GRIK4,KHK,IPO5,MEF2C,NF1,CLDN11,TTLL7,RPS6KA2,SH3BP2,PPP1R9A,ZSWIM8,ZNF423,PSD3,CLIP2,SLC13A3,KAT6A" Drug 6147_DN Tropine [120-29-6]; Down 200; 28.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABAT,BRAP,AMT,APBB2,PPP4R4,BTRC,INA,RAB33A,CLCN4,CRMP1,SLITRK5,EDRF1,MAML1,CNNM1,PLXNC1,PCOLCE2,C3orf18,ST3GAL6,PDLIM5,GAA,SEPT9,SPACA9,GRM1,SLC2A6,TJAP1,IL6ST,ZNF862,NEK1,NELL2,OMG,RETREG1,PRKCZ,RIPOR1,PPM1E,SNCA,ARHGAP26,DBNDD2,STX1A,JMJD6,DNMBP,AP4E1,PARD3,VIPR2,LMF1,ZIC3" Drug 2537_DN Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABAT,NDRG2,TRMT9B,CFLAR,SCAPER,CDH10,HOMER3,CTNND1,MED24,RABGAP1L,CDON,FEM1B,EFNA3,SORBS3,TUBD1,RASGRP2,RACK1,ZNF589,TRAF3IP2,SEPT9,MSL3,CACFD1,MYT1,NEFH,NUMA1,CDK14,PIK3CD,PLEC,PRKAB2,GTDC1,C12orf49,SBF1,MRAS,WDTC1,DBNDD2,TROVE2,SZT2,SLC44A1,R3HDM1,ZMYND8,FLRT2,VIPR2,NSD2,XRCC4,ACTR3B" Drug 1989_DN Antipyrine [60-80-0]; Down 200; 21.2uM; HL60; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ACLY,NDRG3,NDRG2,EP400,APP,NCOA1,CFLAR,CHRNB2,TMEM184B,CSNK1E,PUM1,ZNF337,RCAN1,DCTN4,PLEKHO1,PDLIM5,FAM49B,CELF1,OGA,LILRA2,GRB10,MAP4,MBD1,MITF,PIK3R1,RC3H2,PRPSAP2,PSMD13,NEK11,ATXN2,TRA2B,PAAF1,SIRT2,ELMO2,SMARCA4,MAPKBP1,ERC1,SS18,TSN,UBE2H,CLDND1,LMAN2L,AAAS,FXR1,RNF146" Drug 1168_UP LY 294002; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "AP1B1,CDC42BPA,ANK3,PKP4,GAS7,CDK10,ARRB1,ZSCAN18,NCOA1,ZMYM4,NMT2,SULT4A1,CNTFR,ARHGEF10,PDE4DIP,DAPK3,B3GAT3,KIAA0753,PARD6A,DTNA,ANKRD46,RASGRP2,GAD2,NEU3,AHDC1,GLYR1,GLS,KCNQ3,MAPT,CCSER2,PTK2,TRIM68,SEC14L1,SUPT20H,PREX2,SLC9A5,SNAP25,ZCCHC24,DBNDD2,SPTAN1,SS18,CBX5,PARD3,TPM3,PHTF2" Drug 1803_UP Epirizole [18694-40-1]; Up 200; 17uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "OGT,PPFIA1,ATM,CFLAR,MTMR2,KRIT1,CDH2,LARGE1,SOCS6,ZFYVE9,KIAA1549L,CLCN4,CLTB,CREM,GPRASP1,SPOCK2,HIPK3,ING4,RRAGB,FGF1,HBS1L,ERAP1,GART,SESN1,EML4,HPS5,INPP5B,JAK2,MBNL1,LRP12,MAPK7,TMEM260,RBBP6,ITSN1,RAB3GAP1,ZNF415,PEG10,SS18,TGFBR3,TPD52,METTL3,TRIO,FIP1L1,UBE3B,AAAS" Drug 1939_DN Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "RBM10,ACTN1,AP1B1,PLA2G6,CDH2,CREM,PPP6R2,TM9SF4,SGSM2,EXOG,DYNC1I1,RCAN1,DNAJB6,ENO2,ETV1,WAC,PRKAG2,TRAF3IP2,CRCP,GLS,GRIK5,MAN1B1,IPO5,SCAMP5,MITF,SETD4,PAK3,PDE4A,PDPK1,CCSER2,GPSM2,PMS2,RIPOR1,SAFB,CLSTN1,SLC11A1,ELMO2,CLUAP1,TAB2,ATP10B,IQCE,TK2,PITPNB,ZNF24,PRDM2" Drug 5833_DN (-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "RBM10,ADD2,APBB2,ASPH,BACH1,WHRN,NRG2,CSNK1E,RUSC2,G3BP2,TRAPPC9,FGFR1,GART,PRRC2B,RASSF8,ITPKB,IPO5,SCAMP5,NF1,NUMA1,SLC25A23,MAPKAP1,MAPK7,CNNM2,LRRC49,RAB3GAP1,BTBD7,CDK5RAP2,THSD1,MAPK8IP3,EXOC7,DNMBP,CAMSAP2,TRIM2,TNS2,ATP13A2,TNS1,TRPC1,HIRA,PLPPR2,LMF1,XRCC4,TRIM9,ACTR3B,AAAS" Drug 6846_DN "Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABHD6,ALCAM,DOC2A,BIN1,MARK4,ALDH4A1,CFAP410,CDC42,CACNA2D2,SRSF11,ASIC3,TAOK2,CSF1R,SDC3,GREB1,RIMS2,SLC12A6,EDNRA,HIPK3,FHL1,IQCG,INPP5K,GLS,POLL,GNG4,ITPKB,KCNH2,KCNJ3,NF1,PCDH9,FSD1,MINDY2,PRODH,RELN,RAB3IL1,SLC9A5,MAPKBP1,TSPYL2,CRTC1,TK2,RBFOX2,UBE3A,ZIC3,NUP214,SSPN" Drug 2571_DN Lithocholic acid [434-13-9]; Down 200; 10.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG2,GRAMD1B,MTUS1,DOC2A,CDC14B,ARRB1,PDE8B,N4BP2L1,CACNA1A,CHN2,CPS1,CREM,MRNIP,ELN,LRRC23,DLC1,SPACA9,MDM4,MEF2C,AFDN,N6AMT1,NPR2,NRGN,ENPP2,CCSER2,PPARA,SYTL2,PTAFR,SEC14L1,ZNF821,CNKSR2,EPN2,IZUMO4,DDN,SS18,MAPK8IP3,NSD1,CRTC1,SLC44A1,TLR4,CDK20,TPM3,LMF1,STMN4,PLSCR4" Drug 1344_UP Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "MADD,NCOA1,ST3GAL5,ARHGAP33,STOML1,CLTB,DCTN1,TNK2,ERCC2,FGFR1,SEPT9,CLASRP,SLC2A6,MAP4,SLC11A2,NUCB1,ST8SIA5,PTPA,RIPOR1,ZCWPW1,ZDHHC14,MYH14,PLPPR3,DHX30,ARFGAP1,SMARCC2,MYH15,MAPKBP1,KDM4B,IZUMO4,PBLD,STX1A,VAMP1,SYN2,ATP11A,KAZN,TBL1X,TCF7L2,OBSL1,CRTC1,CBX5,TNS1,ZMYND8,CLIP2,SF1" Drug 1151_UP alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "MTUS1,ARNTL,PDE8B,MTMR3,CAPN3,MAP7,KYAT1,SLC16A4,PICK1,MAGED1,CREM,SIPA1L1,DAPK1,KIAA0753,RUSC2,DTNA,EFNB3,RASGRP2,TRMO,ERAP1,USP19,LAMA2,NINJ2,P2RX7,PILRA,POLG,RAD52,GALNT10,ITSN1,ZNF365,PPP4R3A,SNCA,ZC3H13,ZBTB43,RAP1GAP2,FCHO1,EXOC7,SZT2,GPR161,TMOD1,CADM1,FLRT2,VIPR2,ST7,PHTF2" Drug 3218_DN Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,APBB2,APP,ARHGDIG,RGS20,MARK4,ALDH4A1,MPDZ,CDK5R1,SCAPER,SRSF11,NMT2,FADS2,HOMER3,SH2B1,CRY2,PDE4DIP,SDC3,DAPK3,CDKL3,KIAA1109,GABRA2,GRB10,IGSF1,MDM4,KITLG,MMP16,NPR2,PCDH9,PPP5C,PEX5,NEK11,WLS,ZNF821,FUZ,NLGN1,ZKSCAN3,ZHX3,UNC5B,STX1A,VGF,VIPR2,LMF1,HPS4,SMIM8" Drug 1289_UP Clozapine [5786-21-0]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABAT,ALAD,BIN1,CDC42BPA,APP,KRIT1,STOML1,SIPA1L1,VCAN,RCAN1,DTNA,EIF5,KAT8,PDLIM5,CELF1,POLL,GPR19,GRIK5,ELOVL5,MKLN1,NEK1,NUMA1,SSH1,PLCB2,PTAFR,RAB3IL1,RNH1,TCP11L1,RPS6KA2,SH3BP2,RAB3GAP1,BTBD7,WDTC1,CDK19,RGL1,KAZN,DNMBP,TCF7L2,KAT6B,TPD52,SMUG1,FLRT2,SF1,MKRN3,MAP3K12" Drug 2217_UP Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "KIAA1324,MRTFA,BEGAIN,GAS7,APLP1,PPP4R4,CFLAR,FUBP1,BTRC,QKI,CRMP1,SPOCK2,DMPK,ATN1,HIPK3,MBNL2,TPK1,OGA,DISC1,RND1,GNG3,NR3C1,ITGA7,KCNJ4,KIF5A,MYCN,NELL2,PCBP3,PDGFRA,PLCD1,PLP1,RAD52,ASAP3,RPH3A,SLC2A5,LIMS2,SLC11A1,LIMCH1,CDK19,ABCC8,TACC1,SZT2,CRTC1,R3HDM1,TRPC1" Drug 7391_DN 0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADRB2,AP2A2,MYRF,KYAT1,ARHGEF1,TPP1,NMT2,HOMER3,AKAP7,RCHY1,SLITRK5,DLG3,CDON,DTNA,EN2,EPB41L1,SPEG,ST3GAL6,BAIAP2,TRMO,FAM49B,TMEM8B,AHDC1,GPR37,MUM1,JAK2,GPSM2,PLCD1,FSD1,MAPK7,SAMD9,BCAS3,PTHLH,RGS3,RGS10,KDM4D,SHANK2,CDK19,ZBTB43,DNMBP,AHCYL2,PARD3,NSD2,NAV3,PHTF2" Drug 1861_DN Triamterene [396-01-0]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASIC1,ADRB2,AP2A2,ZSCAN18,SYNJ1,ARHGEF7,SCAPER,SOCS6,NIPBL,DCAF8,MATR3,KIAA0586,SPATA2,B3GAT3,KIAA0753,FAM13A,VPS26C,FGFR1,ATP2C1,CELF1,CGREF1,HBS1L,ERAP1,GLS,PSRC1,PRRC2B,NUDT21,ARHGAP19,JAK2,NFYA,ODF2,OGG1,OPA1,PPP3CB,PTAFR,RAB3GAP1,MAPKBP1,ZBTB43,POGZ,MAPK8IP3,PDLIM2,NACC2,ZMYND8,EPM2A,ZNF248" Drug 3353_DN Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "AK2,LTBP4,DOC2A,AMPD3,APLP1,MARK4,SLC2A11,CFLAR,FUBP1,NEURL1,CLGN,ARHGEF4,PPP6R2,MAML1,ARMCX2,MED12,RCAN1,SUGP2,ING4,CDKL3,STRADA,SEPT9,RAB30,GNG3,GPR19,KCNN2,MPP2,MAPK7,SYTL2,TCP11L1,RPS6KA2,PKNOX2,KIF13A,ZCCHC24,EMC1,SEMA4A,MCF2L,SMG6,DICER1,TK2,PLPPR2,KLC2,XRCC4,ZNF45,SYNC" Drug 4683_UP Acyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "MRTFA,DOC2A,AMPH,APBB1,APC,RASL11B,NOL4,ADGRB2,BMP7,CACNG1,CDH10,CHM,DNAJB5,AKAP5,EDRF1,EZH1,TBR1,GAD2,CSDC2,GPR17,GPR19,TPPP,GRM1,AP4S1,JAK2,KCNC1,KCNN1,VWA5A,ADAM11,NFYA,PDE4D,PDGFRA,RGS12,PBRM1,ZHX3,SS18,ATP11A,SLC44A1,TPM1,CDK20,TPM2,NSD2,ZNF225,SEMA3B,PHTF2" Drug 1416_UP Chlorzoxazone [95-25-0]; Up 200; 23.6uM; HL60; HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG2,SLC4A4,KIF1A,CACNA1A,CALB2,SPAG9,CNTFR,IQCK,CHD5,CTIF,TMCC2,DLG3,TRAPPC9,ATN1,SORBS3,ELN,C1orf61,AGAP2,GJB1,GNAO1,CACFD1,GSTM5,TJAP1,KCNF1,LAMA2,MDFI,GIT1,SAMD14,NELL2,KCNK10,PBX1,CAMKV,PRRX1,PACSIN1,PPARA,PLPPR3,RXRA,LIMS2,FAM214B,PHLDB1,SYN2,LILRA4,VGF,VIPR2,NUP214" Drug 5795_DN Demecarium bromide [56-94-0]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "EP400,PDE8B,ALDH4A1,NRXN3,CSF1,VCAN,SMG7,DLG3,EDNRA,HIPK3,ANKMY1,TUBB4A,IQCG,ANKFY1,CINP,B4GALNT1,ERAP1,USP19,HNMT,ICA1,IL11RA,MATN3,GIT1,NF1,NUMA1,PBX1,PIK3R1,NLE1,BEND5,FBXW7,PAQR6,ASAP3,PEX26,ELMO2,ZKSCAN3,SPTAN1,CAMTA2,SYT1,COBL,WSCD1,SZT2,TRPC1,HIRA,EMSY,HPS4" Drug 2151_DN Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG2,MRTFA,MARK4,ASPH,BCL7A,SYNJ2,CACNA1A,USP2,ARHGAP33,ZFYVE9,PLAA,STOML1,CREM,CSF1R,MICAL2,DGKG,ERCC2,KAT8,FLT1,AFF2,CSPG5,GAB1,WASF3,AHDC1,POLL,SLC2A6,GIT1,PLTP,RAB3IL1,RAP1GAP,GALNT10,SH3BP2,ITSN1,EPN2,FAM214B,SLC11A1,WDTC1,ZCCHC24,FAM168A,RBFOX2,TPM1,VIPR2,XRCC4,EVI5,ST7" Drug 3541_DN Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABHD6,AK2,EPB41L5,PPFIA3,PDE8B,STX16,CFLAR,SCAPER,NEURL1,SOCS6,SLC4A7,DZIP3,RCAN1,EFNA3,EN2,VPS13B,NCALD,ZNF589,BAIAP2,FLNC,PDLIM5,OGA,MSL3,NR3C1,HNMT,HSD17B1,IGSF1,IL6ST,INPP5B,LIG4,KITLG,NF1,NNAT,ODF2,OPCML,PALM,PPARA,PEX5,EMID1,MAPKBP1,KIF13A,WDTC1,AJAP1,CHST8,VLDLR" Drug 6760_DN Adenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "FAM131A,ATP1A3,BACH1,BAIAP3,CBFA2T2,NRXN3,CLCN4,ENTPD4,PDE4DIP,CNTNAP2,CTNND2,RABGAP1L,EDIL3,EDNRA,HIPK3,EFNA3,PLXNC1,AASS,ST3GAL6,GAB1,LYVE1,GPD2,STON1,GRK4,GRM8,KLF12,ICA1,INPP5B,MDM4,LRRN3,RGS10,ASAP3,SHANK2,PEG10,ARHGAP26,ZBTB43,MAPK8IP3,ASTN2,CHST8,METTL3,TRIO,AMACR,VIPR2,PRDM2,PHTF2" Drug 3136_DN Trapidil [15421-84-8]; Down 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "C1QTNF3,PDE8B,B4GALT6,RAB28,ZFYVE9,CNTN1,OSBPL3,ARHGAP32,SPOCK2,TRAPPC9,RCAN1,EIF4G2,KIAA1109,CAMSAP1,CSPG5,GAA,INPP5K,AHDC1,RND1,GPD2,MAP4,MBNL1,NOS1,ODF2,PDE4D,RETREG1,SLC25A23,ZSCAN32,BEND5,RNASEL,SBF1,ATXN1,SLC1A7,CCDC88A,ARFGAP1,ZKSCAN3,TMCC1,ARHGAP26,DBNDD2,IQSEC2,CDK19,KCTD2,BEST1,LMF1,MKRN3" Drug 1840_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ACTN1,PPFIA4,MARK4,N4BP2L1,ATP6V0A1,SCAPER,CACNA1A,SRSF11,RAB33A,FEZ1,SLITRK5,DAPK1,SPATA2,SMG7,SIDT2,EFNA3,PLXNC1,ZNF589,OLFM1,ALDH1L1,GLYR1,RAB40B,HMGB1,TJAP1,KCNQ3,MAP4,SCAMP5,GIT1,MINDY2,CNTLN,RAB3IL1,RGS3,RPS20,SEMA6D,SLC1A6,FAM214B,BTBD7,DOK5,ZHX3,SLC19A3,KCTD2,REEP1,ADAMTS9,ST7,PHTF2" Drug 2393_DN Prednisolone [50-24-8]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG2,C1QTNF3,ALK,CDK13,MARK4,NCOA1,NUMB,N4BP2L1,RIPK1,LDLRAD4,CD86,ARHGEF1,FOXN3,ZFYVE9,IQCK,SPATA2,DNM2,MBNL2,SORBS3,EIF5,TESK2,ZNF589,FYN,ALDH1L1,USP19,MSL3,MAP4,TMEM231,RAB3A,RALGDS,FAM184A,RGS10,MYH14,GSTCD,PAQR6,SH3BP2,AMBRA1,SLC1A7,PPP4R3A,DDN,ZC4H2,TCF7,HIF3A,SLC44A1,KAT6B" Drug 7345_UP Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADORA2A,NME5,PLA2G6,CAPRIN2,MTMR3,BAIAP3,CAMK2G,NEURL1,RAB33A,CRY2,NCOR2,PDE4DIP,ARHGEF4,SEC14L5,HDAC9,DENND4A,FER,CAMKK2,SIGLEC8,RND1,POLL,GNG3,LPAR4,GRIK5,GRM8,ATXN2L,INPP5B,GIT1,NF1,CNOT4,NTRK2,PDE4B,PRPH,ZSCAN32,FAM120C,RIPOR1,ROM1,ATP10B,PHLDB1,WSCD1,BHLHB9,ZKSCAN5,MAP3K12,STMN4,HPS4" Drug 5104_DN Flumequine [42835-25-6]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "MTUS1,EIF4G3,FUBP1,BTRC,MAP7,CCNT1,SCARB1,CHN2,BAG4,CREM,EDRF1,RIMS3,DAPK3,DNAJC6,DLG3,EDIL3,FCF1,IRAK4,EML1,EPHA5,ETV1,ANKMY1,F3,FER,TMEM8B,AGFG1,HSF2,IL6ST,KCNN1,NUMA1,PDE1C,STRN3,CNNM2,SEC61A2,SUGCT,KIRREL1,ZNF671,SUPT20H,SS18,DIP2A,KAZN,KIAA1107,ZNF24,ZBTB38,KAT6A" Drug 5418_DN Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ATM,ALDH7A1,CFLAR,SYNJ2,ADGRG1,PLEKHB1,RAB28,CHD1L,SH2B1,MFAP3L,SMG7,SIDT2,ZNF589,DISC1,GPER1,ATXN2L,IL6ST,IPO5,MAP4,MBD1,MITF,PMS2,FAM120C,RPS6KA2,SEC14L1,ASAP3,SLC1A7,EPN2,BTBD7,SLC20A2,COA1,LIMCH1,KIF13A,KDM4B,TTBK2,PLCB1,RPGRIP1L,TNS2,TMEM121,CHST8,RBFOX2,HIRA,VLDLR,GDPD5,PHTF2" Drug 3516_DN Rimexolone [49697-38-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,APC,CDK10,STX16,SCARB1,QKI,CREM,CSF1,PPP6R2,RIMS3,FBXL5,RUSC2,SMG7,TOM1,FCF1,EFNA3,MRNIP,EZH1,PDLIM5,PRELID3A,HBS1L,COPS8,MSL3,GRB10,CACFD1,HSD17B1,KCNJ3,KITLG,NEK1,NF1,NUMA1,PMP22,PRPH,ZDHHC14,WLS,ATXN2,FERMT1,CDK5RAP2,KIF13A,MAPK8IP3,TCF7L2,RPGRIP1L,AP4E1,TK2,KLC2" Drug 2019_DN Edrophonium chloride [116-38-1]; Down 200; 19.8uM; HL60; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADRB2,AP1B1,ATM,CANX,KRIT1,CDC27,RCBTB2,CHRNB2,EPS15L1,QKI,PREPL,RUBCN,DCAF8,TBC1D5,MAML1,DBT,DMTF1,DTNA,FEM1B,PHF20L1,DENND4A,ZNF44,PRRC2B,DIDO1,NR3C1,NFE2L2,SETD4,FTO,TRHDE,POLG,RPRD1A,PEX26,CCDC88A,SMARCC2,SON,ERBIN,SYPL1,TACC1,MCF2L,EXOC7,AGTPBP1,CBX5,TSC1,HIRA,SF1" Drug 6979_DN "radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "OGT,EP400,ZBTB10,ATM,BCL7A,SCARB1,LHX2,MICAL2,SOCS5,DCAF8,MED24,PARD6A,RABGAP1L,DMTF1,RASGRP1,RBM12,EGR3,IRAK4,TNK2,PCOLCE2,PLEKHO1,CINP,GART,TXNL4A,HNMT,MEIS1,NFYA,PIK3R1,MED1,SYTL2,SIDT1,ARID4A,RET,RNASEL,SEC14L1,DHX30,WDTC1,SOX3,FNBP1,ZSWIM8,CAMTA2,NCDN,ARHGEF9,BHLHB9,PMEPA1" Drug 1855_UP Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,PPFIA1,PPP4R4,ARRB1,ALDH4A1,N4BP2L1,BMP7,C5,CAMK2G,TPP1,CNTFR,ARMC8,CREM,DAPK1,ZBTB24,SIDT2,TAOK3,FECH,WASF3,SRCAP,DBF4,ICA1,LSS,NEFH,ENPP2,PPP5C,TMEM104,CNTLN,PTPRN2,PLPPR3,TRA2B,SH3BGR,FUZ,DZIP1,PEX26,ZNF667,TMCC1,TSNAXIP1,DBNDD2,ZEB1,SMUG1,TRPM2,BCL2L13,MAP3K12,EPM2A" Drug 2941_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABHD6,CDK10,ATP6V0A1,MTMR3,CAMK2B,HIP1R,ARHGAP33,ZFYVE9,CLCN4,ARMC8,PDE4DIP,CTNND1,TBC1D5,DLG4,TRAPPC9,EDNRA,ETV1,OLFM1,INPP5K,GLS,MSL3,GNG4,ATXN2L,KCNB1,KCNH1,AFDN,ADAM22,NINJ2,CNOT4,NECAB2,TNPO2,PTAFR,RAB3A,BSDC1,FOXRED2,RASA3,ST6GAL1,SLC1A3,SHANK2,WDTC1,ZC3H13,SPTAN1,RAP1GAP2,THRA,RBFOX2" Drug 2876_UP Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASIC1,ADORA2A,APAF1,PLA2G4C,CFLAR,GYG2,NEURL1,CDH10,GSDME,TMCC2,SHANK1,SNX29,TENM1,C3orf18,HSD17B14,CEND1,F5,AFF2,KHDRBS3,POLL,GPR22,RASSF8,HLF,VWA5A,MYO7A,NNAT,NUMA1,PACSIN1,PPARA,MINDY2,CEP41,PRKAR1B,PRKCB,MASP1,PTN,EMID1,DGLUCY,SATB1,SCN8A,ST6GAL1,ARHGEF40,ATP11A,PARD3,FAM155A,DPF3" Drug 1620_DN Chlormezanone [80-77-3]; Down 200; 14.6uM; HL60; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADD3,OGT,SHTN1,ATM,RAB29,LRBA,CDC27,NIPBL,ARMC8,KIAA0753,G3BP2,TRAPPC9,RCAN1,SUGP2,EPB41L2,ERCC2,TESK2,CAMSAP1,FAM49B,SEPT9,GART,DBF4,MYO9A,ENPP2,CDK14,STRN3,LRP12,RETREG2,GTDC1,SBF1,SFPQ,ASRGL1,HSPA4L,SGK1,BTBD3,WDR47,SMARCA4,KDM4C,UNC5B,STAU1,TBL1X,ZNF24,ZNF189,RNF103,SNX27" Drug 1738_UP Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; HL60; HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "PLA2G6,C1QTNF3,MRTFA,CNTNAP1,PDE8B,SLC4A4,ATP2A2,CADM3,ADAM15,MYRF,INA,AP4M1,ABCG2,EDRF1,SPOCK2,SIDT2,KAT8,ZNF589,OLFM1,PRKAG2,C1orf61,NSG1,B4GALNT1,TMEM8B,GART,GNAO1,LILRA2,KCNN1,IPO5,AFF1,PTOV1,NTRK3,RC3H2,ZNF821,FAM214B,ZCCHC24,ZC3H13,SPTAN1,GANAB,ARHGEF9,PLCB1,WWC1,SEZ6L,SSBP2,CAMK1G" Drug 6238_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "OGT,ATM,C5,SCARB1,TAOK2,RAB26,CREM,SOCS5,GREB1,DCAF8,SGSM2,RCAN1,MAMLD1,SIDT2,CELSR3,EPB41L1,SEMA4D,DISC1,INPP5K,GHR,MAP4K5,HSF2,NUCB1,PMP22,RETREG2,POLG,RAB3IL1,ROBO1,FOXRED2,ITSN1,AMBRA1,KDM4B,SOX3,CLASP2,NCDN,FAM168A,SIN3B,AHCYL2,TIAM1,KAT6B,VAV1,XRCC4,NDRG4,UPF3A,GDPD5" Drug 1539_DN Haloperidol [52-86-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ATM,BTRC,PLEKHB1,NMT2,ARMC8,COL4A5,ARHGEF10,SIPA1L1,PDE4DIP,DZIP3,SDC3,ARHGEF4,GPRASP1,DAPK3,HIPK3,SUGP2,MBNL2,SORBS3,DENND4A,EZH1,PDLIM5,GLYR1,GRB10,CACFD1,ATXN2L,LYRM9,NDUFA5,NRGN,NLE1,MBOAT7,PPP5C,TMEM104,ROM1,FBXW7,FUZ,EPN2,BTBD7,SOX3,FNBP1,CLSTN2,POGZ,PLCB1,TMEM121,TPM1,TRPC1" Drug 1292_UP Clebopride maleate [84370-95-6]; Up 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "CDC42BPA,ANK3,SLC4A4,ATP2A2,MTMR3,CFAP410,KYAT1,STOML1,PICK1,WHRN,COL9A2,ARHGEF10,CSNK1E,ZFYVE16,SGSM2,DTNB,FAM13A,COQ7,ZNF589,GAA,SRCAP,AHDC1,ZNF276,POLL,GRIK5,IFI16,NPR2,PIK3CD,STRN3,PPP5C,PTAFR,RGS3,PPM1E,FUZ,URGCP,PEX26,SMARCD3,IZUMO4,UNC5B,ATP11A,SIN3B,TCF7L2,ATP13A2,KCTD2,TNS1" Drug 432_DN 17-AAG; Down 200; 1uM; PC3; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG2,SPARCL1,ANK1,ASCL1,BMPR1B,CDH18,CLTB,IFFO1,SRGAP3,DMPK,DRP2,ATN1,TNK2,ELAVL4,LRRC23,FABP7,OLFM1,GBX2,AHDC1,MCHR1,GRIK5,AP4S1,AFF1,ADAM22,MX1,MYL3,OPRL1,CDK14,MAPK7,ARHGEF10L,RNASEL,TCP11L1,TMEM156,ATXN1,ASRGL1,ASAP3,SIRT2,FNBP1,CDK19,MCF2L,WSCD1,SEZ6L,VIPR2,WIPF1,SLC17A7" Drug 5288_UP Debrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASPHD1,APP,ASPH,ATP2B1,ATP6V0A1,BCL7A,SYNJ2,SCAPER,KYAT1,FOXN3,TAOK2,CDC42BPB,RNF14,NCOR1,NCOR2,VPS26C,F3,AGAP2,STAG2,NCKAP1,SEPT9,HTATSF1,PRRC2B,NR3C1,HNMT,LSS,MAP4,NRGN,OGG1,PC,SLC25A23,MTRF1L,LRRC49,RAB3A,BSDC1,PEX26,WDTC1,SPTAN1,TRIM2,CLASP1,TMOD1,KAT6B,WBP2,XRCC4,WNK1" Drug 443_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "AP2A2,APBB2,APP,ARRB1,CADM3,DLGAP1,CHRNA4,JAM2,APPL1,SEC14L5,KLHL3,DTNA,PIPOX,FAM49B,RUNDC3A,GPM6B,GRIK5,SCIN,MAOB,MMP17,ADAM22,NACA,NAP1L1,NOVA1,PLCD1,RETREG2,PPP2R2B,PRODH,CNNM2,PTK2,RET,RGS3,RLBP1,FOXRED2,SEMA6D,FUZ,ST6GAL1,SLC9A5,KBTBD4,SLC12A2,SLC15A2,SLN,POGZ,CDH22,STMN4" Drug 3206_DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "AP2A2,AK2,PLA2G6,APOC1,APP,CDK13,SCAPER,BTRC,CFAP410,SPAG9,USP2,SCARB1,SOCS6,QKI,HOMER3,WHRN,SLC4A7,PDE4DIP,DAPK3,MFAP3L,TOM1,FCF1,GABRA2,MALT1,GLS,POLL,GRM8,KCNH2,MATK,MDM4,MIA2,KITLG,PDE4A,PLTP,PTCH1,CEP97,RGS12,NXT2,ARHGEF9,EXOC7,TMPO,CDK20,TRIO,ZKSCAN5,EVI5" Drug 7017_DN Mesoridazine besylate [32672-69-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ABHD6,APP,BCL7A,ARHGEF7,PTBP2,SLC4A7,DNAJC6,LYPD1,DSCAM,EFNA3,EIF5,MRNIP,MFSD10,FGFR1,SRCAP,MSL3,MAP4K5,JAK2,MAP4,MAPT,MITF,NUMA1,OCRL,PC,SSH1,CCSER2,SLC25A23,STRN3,GTDC1,TRAPPC13,PEX26,ZKSCAN3,SOX3,SS18,COBL,PDLIM2,WWC1,TCF7L2,PCDHA6,TRIO,VGF,XRCC4,PARP6,MPPE1,MVB12B" Drug 5279_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ACTN2,AK2,BCAS1,CDK10,CLU,FADS2,DNAJB5,CNTN1,ABI3BP,ATRNL1,EXOG,EDNRA,EGFR,DMTN,LRRC23,CDKL3,ACSL4,DLC1,GPR153,GAB1,GRB10,INPP1,KIF5A,LMO2,VWA5A,MAOB,KITLG,MPP2,ADAM22,P2RY1,PENK,RETREG1,RAB3IL1,RPS20,SH3BP2,DOCK10,KDM4C,ZC3H13,CDK19,MCF2L,EXOC7,SYNE1,TMOD1,RUNDC3B,MPPE1" Drug 6614_DN Apramycin [37321-09-8]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "RALGAPA1,MRTFA,BIN1,APBB2,SYNJ2,RAB29,MAP7,RAB28,CLCN4,HOMER3,AKAP7,WHRN,CREM,ARHGAP32,DBN1,ZNF589,BAIAP2,SEMA4D,GBX2,GLS,POLL,L1CAM,MAPT,AFDN,GIT1,PC,PDE4D,PIK3R1,CCSER2,MAPK7,MAPK8,RAB3A,RAD51D,FBXW7,RPS6KA2,WDTC1,LHPP,MAPK8IP3,GSE1,CABIN1,TRPM2,RPRM,UBTF,NT5M,NAV3" Drug 3441_UP Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NME5,DOC2A,AMT,GAS7,ARHGDIG,RASL11B,ATM,SLC4A4,CFLAR,CACNB2,CLGN,CHRNB2,ZFYVE9,STOML1,ARHGEF6,GREB1,ARHGAP32,HDAC4,ZNF804A,RCAN1,HIPK3,GPR153,HBS1L,SEPT9,GLYR1,LIG4,MIA2,NOVA2,NRGN,PLEC,PPARA,PLPPR1,RAB3IL1,ZDHHC14,RGS3,TRA2B,PPP1R9A,SLC1A7,KIF13A,TBL1X,SZT2,PCDHA6,METTL3,EMSY,UBE3B" Drug 5028_UP Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ADORA2A,AGT,MARK4,RASL11B,ST3GAL5,GYG2,CRLF1,PLAA,CNTN1,AKAP7,RCHY1,DCAF4,RUSC2,ATN1,RCAN1,SGK2,HIPK3,SIDT2,MBNL2,ERCC2,FGFR1,ALDH1L1,GLYR1,POLL,GNG4,PRUNE2,KCNH2,KHK,KIT,MDM4,NOS1,PDE3B,PDE4D,PIK3CD,MINDY2,MAPK10,MYH14,CARF,PKNOX2,SLC11A1,COA1,TRIO,LMF1,KCNAB1,EPM2A" Drug 5984_DN Meticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "NDRG3,BRAP,AK2,APBB2,ALDH4A1,ATM,STX16,CFLAR,SYNJ2,MTMR2,B4GALT6,HOMER3,BAG4,CREM,PDE4DIP,GREB1,DBT,MBNL2,KAT8,SEMA4D,ANKFY1,GLYR1,GLS,MSL3,HTATSF1,IL6R,POLG,MINDY2,ELOVL2,RAD51D,GTDC1,RGS10,ZNF430,ZBTB43,SS18,TTBK2,TCF7,AHCYL2,CHST8,TMPO,TPD52,ZMYND8,UBTF,VAV2,EMSY" Drug 5323_UP Primidone [125-33-7]; Up 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "ASPHD1,ASIC1,APBB2,PLA2G4C,ASPH,CFLAR,ST3GAL5,MTMR2,BTRC,CAMK2B,KYAT1,ADGRG1,AKAP7,DSCAM,EGFR,EPB41L2,ZNF589,FGF12,FGFR1,BAIAP2,DISC1,MALT1,ZNF276,ATXN2L,ELOVL5,KCNJ3,MDM4,MOBP,NF1,OGG1,KCNK10,PLCD1,MBOAT7,GON4L,NKAIN1,ABLIM3,RPH3A,BTBD7,SYN2,ASTN2,CABIN1,ZMYND8,UPF3A,MAP3K12,KCNAB1" Drug 7310_UP Chenodiol [474-25-9]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "APC,ATM,RUNX1T1,FOXN3,CHM,TAOK2,HOMER3,CTNND2,KBTBD11,HIPK3,MBNL2,DCTN2,GAD1,GPR17,GUCY1B1,MAP4K5,ATXN2L,HSF2,INPP5B,KCNMA1,KIF5C,LIFR,ZNF862,NFYA,CCSER2,PPARA,MAPK8,SYTL2,PTPN13,TMEM231,TTLL7,RASA3,SCG5,FNDC3A,SLC14A1,BTBD7,TSNAXIP1,THSD1,NXT2,TIAM1,OSBP2,WIPF1,XRCC4,KCNAB1,SENP7" Drug 5622_UP Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 4.91E-03 1.00E+00 2.61E-02 2.97E-01 45 196 "DPF1,BIN1,ARHGDIG,NRP2,CAMK2B,CD86,ADGRG1,IFFO1,AATK,RASSF2,ECM2,FGF1,GPR153,NSG1,FUT9,ATP8A2,C1QL1,GPR37,PCLO,RAPGEF1,SPACA9,CACFD1,GRM1,DHX35,SHISAL1,KCNK2,KCNMA1,KCNN1,MMP17,FXYD7,NCAM1,PCDH9,CEP41,PTAFR,RGS12,SYNDIG1,SH3BP2,SLA,LIMCH1,WSCD1,ICAM5,XRCC4,SPHK2,DPF3,JPH3" Drug CID000004585 olanzapine Stitch 4.91E-03 1.00E+00 2.61E-02 2.97E-01 32 129 "ADRA1D,ADRA1B,ADRB2,BCHE,CHRM1,CREM,DRD1,DTNB,OLIG2,ERBB4,RASL12,GALR1,DISC1,GNAL,MCHR1,GRM2,HRH3,HTR2A,HTR5A,KCNH1,KCNH2,NCAM1,NPY,PDE4B,GPR85,MAPK3,MAPK4,MAPK7,PRODH,RGS7,NPAS3,SST" Drug CID000219132 3-Nitrobenzaldoxime Stitch 4.92E-03 1.00E+00 2.62E-02 2.98E-01 29 114 "APLP1,ALS2,CANX,AIFM1,CNTFR,RCHY1,NRN1,DNER,NEU3,GPR162,GFAP,GRIA1,GRIA4,GRIK1,GRIK5,GRIN1,HPCA,KCNJ10,LIG4,NEFM,NFE2L2,NOS1,NOVA1,NTRK3,SLC1A2,WDTC1,HECW1,ZFP91,TUBA1A" Drug ctd:D010261 Paraoxon CTD 4.93E-03 1.00E+00 2.62E-02 2.98E-01 30 119 "ACHE,AXIN2,APC,ARHGDIA,BCHE,CHRM1,CHRNA4,CHRNB2,CNR1,ACBD5,AKAP12,SUGP2,PTK2B,FGFR1,GAP43,GSTT2,HSP90AA1,ICA1,MDM4,NEFH,SLC1A2,SLC1A3,SYN1,SYP,TAC1,TCEA1,TPM4,AMOT,LAT2,SRGAP2B" Drug 3665_DN Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "APC,SEMA4G,SLC4A4,IL33,BTRC,HAP1,CBFA2T2,SCARB1,SOCS6,ARMC8,SH2B1,HAPLN1,SLITRK5,GPRASP1,RHOBTB1,SMG7,EDNRA,CNNM1,EFNA3,EML1,SCARA3,GBX2,SRCAP,GPM6B,GPER1,HAS2,MT1M,PRPH,PTHLH,PTN,ENOX1,GAL3ST4,IL17RB,ZNF821,PPP4R3A,CEP68,COBL,EXOC7,TCF4,TMEM121,TK2,SMUG1,WNT7A,RNF146" Drug 261_UP cyclosporine A; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "BRAP,APBA2,KCNAB2,PDXK,ARNTL,ATM,ATP6V0A1,KALRN,CHGA,TAOK2,CLCN4,PDE4DIP,DCAF8,ERCC2,SEC23B,TRMO,HBS1L,GRM3,SOX21,SLC2A6,ARHGAP19,IRF8,KCNQ2,L1CAM,ADAM22,N6AMT1,FXYD6,NF1,NNAT,NUCB2,FAM120C,C1orf54,RGS4,SATB1,FNDC3A,SLC11A1,IFT122,TSPYL2,SYN1,ADGRL3,TEK,TF,WNT7A,EMSY" Drug 5964_DN "ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "ABR,ASPHD1,AP2A2,ALK,BRINP2,CA12,CAMK2B,SCARB1,FOXN3,VAX2,HOMER3,GREB1,DBN1,C2CD2L,ATN1,DTNA,RASGRP1,EFNB3,EGR3,F5,GAD1,SRCAP,IL6ST,JAK2,KCNF1,KHK,LIG4,MMP17,NOS1,NUCB1,PDE3B,RC3H2,PRKAR1B,ELOVL2,RET,KCTD17,RNASEL,FBXW7,MAP6D1,NUBPL,SS18,ARC,LAT2,SLC30A3" Drug 7070_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "ALDH4A1,ATM,MPDZ,BID,SLC25A14,AP4M1,ARMC8,WHRN,TENM4,PDE4DIP,TBC1D5,DBN1,ZNF804A,G3BP2,FCF1,EFNA3,KMT5B,EIF5,TUBD1,ETV1,CHST15,PDLIM5,TXNL4A,GLS,ACOT7,JAK2,CNOT4,NPR2,PAK3,PDGFRA,PLEC,MBOAT7,MAPK7,RGS3,COA1,PDZD2,GANAB,ARHGEF9,SYT1,TRIM2,TST,NDRG4,PCBP4,ACTR3B" Drug 4487_UP Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "ADCY8,TRMT9B,ATP2B2,NRP2,RUNX1T1,CHGA,CHRNA4,PCYT1B,ARHGEF10,MICAL2,VCAN,ARHGEF4,HDAC9,DRD1,EDNRA,RASGRP2,DLC1,ST3GAL6,NSG1,FYB1,ZNF44,SIGLEC8,SPACA9,GRM8,KCND3,AFDN,MYT1,NEUROD1,MAPK7,PTPRB,PTX3,RASGRF1,KHDRBS2,TCP11L1,MRAS,ZNF415,TMCC1,SYT1,SYT5,TRIO,VIPR2,LMF1,KCNAB1,TIGD6" Drug 5970_UP LY294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "C1QTNF3,AMT,ZBTB10,SLC2A11,BACH1,SLC4A7,CRMP1,CRY2,ABCG1,PDE4DIP,SPOCK3,DRP2,SEMA3D,AASS,MRNIP,CDKL3,ATP8A1,ST3GAL6,TESK2,ZMYND11,TDRKH,STON1,GRK4,HNMT,SCIN,NNAT,NUMA1,GPR85,SERPINI1,PLCD1,BEND5,MYH14,ATXN1,ZNF334,SLN,MAPK8IP3,CEP68,TTBK2,PHLDB1,TCF7L2,TK2,ZMYND8,MAP3K12,UBE3B" Drug 6776_UP Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "AK2,TRMT9B,AMT,CDK13,RGS9,CFLAR,RAB29,SIPA1L1,JAKMIP2,DMTN,PTK2B,PDLIM5,FYB1,RND1,LILRA2,STMN2,ADAMTS13,CACFD1,GRM1,TJAP1,IL6R,JAK2,VWA5A,MAP4,MOBP,MX1,ZNF862,NPTX1,PLEC,PRKCB,PTPRB,ASAP3,NPAS3,MAPK8IP3,PLCB1,TGFBR3,ZNF34,TIAM1,TNS1,UCHL1,KCNK12,ZNF24,PRDM2,KAT6A" Drug 4563_DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "ADCY6,NME5,C1QTNF1,BIN1,MARK4,CFLAR,SCAPER,AP4M1,CHN2,PLEKHB1,STOML1,DNAJB5,QKI,TENM4,FAM131B,TBC1D5,PARD6A,FCF1,CSPG5,PSRC1,STON1,GUCY1A1,HAS2,HNMT,MITF,NDP,PDE1C,SYTL2,PTPRN2,CSRNP3,ZNF667,TNIK,CDK19,CEP68,ARHGEF9,FAM208A,TCF7L2,TMPO,SMUG1,UBTF,WIPF1,ZNF32,TRIM9,HPS4" Drug 1986_UP Thioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "APBB2,CDK10,ASPH,MTMR9,ARHGEF7,CARS,CHD1L,CTH,RUBCN,DAPK1,ZEB2,DPYSL2,KIAA1109,ATP6V1H,ATP2C1,OGA,FYN,SRCAP,GNG3,MAN1B1,LSS,NTRK3,P2RX7,ENPP2,RETREG1,PLCD1,SMOX,TRHDE,PTPA,MAPK3,PCMTD2,RPS6KA2,SGK1,KBTBD4,SPP1,SRPK2,THSD1,FCHO1,VAMP1,TBL1X,KCTD2,PLPPR2,EVI5,MPPE1" Drug 7379_DN Halcinonide [3093-35-4]; Down 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "BRAP,CDK13,ALDH4A1,CFLAR,SYNJ2,ARHGEF1,CLCN3,QKI,KLHL3,LYPD1,DLG3,EDNRA,OPTN,LPAR6,ZNF589,IQCG,FYN,GAD1,SEPT9,GBX2,GPD2,RASSF8,INPP5B,KLC1,MITF,MMP16,MPP2,SLC11A2,PDGFRA,PLCD1,PPP2R5C,BCAS3,PTHLH,PTPN13,ATG16L1,RGS4,ZNF671,TCP11L1,SH3GL2,ARHGAP26,TCF4,TNS2,SSBP2,PHTF2" Drug 3815_DN Methimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.03E-03 1.00E+00 2.67E-02 3.04E-01 44 191 "ADRA1D,PPFIA3,MARK4,ATM,CFLAR,BMP7,CFAP410,CAMK2B,ARHGAP33,PLEKHB1,HOMER3,WHRN,AKAP5,SH2B1,EDRF1,DUSP9,EFNA3,EIF4G2,FAM49B,OGA,HTATSF1,ATXN2L,KIFC3,MAP2,MAPT,MARK1,SCAMP5,NOS1,OPRL1,PENK,KCTD15,EPN1,MINDY2,ACSS3,SEC61A2,RASA3,NTNG1,RPH3A,PREX2,ARHGEF40,COBL,TNS1,VGF,WNK1" Drug CID000002748 NSC-88789 Stitch 5.06E-03 1.00E+00 2.68E-02 3.05E-01 13 39 "VCAN,SLC25A18,EEF1A2,SEMA4D,GLRB,GPT2,GRIK1,GRIN2C,GRIN2D,RPE,SLC15A2,SMUG1,HPS4" Drug CID000005719 zaleplon Stitch 5.06E-03 1.00E+00 2.68E-02 3.05E-01 13 39 "CASP8AP2,MRO,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,SLC6A1,TRIO" Drug CID000122591 E 14 Stitch 5.06E-03 1.00E+00 2.68E-02 3.05E-01 13 39 "CACNA1A,CACNA1B,CALB1,SYNPR,VCAN,NCAN,CALCRL,FCGRT,MSTN,GFAP,PDYN,PENK,BCAN" Drug CID000000482 InsP5 Stitch 5.14E-03 1.00E+00 2.73E-02 3.10E-01 19 66 "ADRA1B,RIPK1,CA4,NGB,CLTC,IP6K1,IP6K2,FOXM1,IP6K3,HBA1,DDX19B,INPP1,ITPKA,ITPKB,PGAM2,RASA3,ARHGAP26,NSFL1C,SYT1" Drug 1323_DN Cefadroxil [50370-12-2]; Down 200; 11uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.15E-03 1.00E+00 2.73E-02 3.11E-01 43 186 "PPFIA1,GAS7,CDK13,STX16,N4BP2L1,CANX,CAPN3,QKI,CTH,ZNF337,HP1BP3,G3BP2,RCAN1,EPB41L2,ANKFY1,GART,COPS8,GLUL,EML4,HSF2,JAK2,LIG4,MBNL1,OLR1,PDE3B,MINDY2,SAMD9,CLIP1,SLC2A5,TAB2,EPB41L3,SS18,NXT2,ATP11A,TLR4,TSN,NSD2,ZNF24,LAMP5,EMSY,MPPE1,NLRP3,RNF146" Drug 6996_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.15E-03 1.00E+00 2.73E-02 3.11E-01 43 186 "ABHD6,NME5,ARHGEF1,CBFA2T2,CRY2,PDE4DIP,CTH,SPOCK3,MED12,SIDT2,OPTN,EGR3,ANKMY1,RRAGB,F3,ARMCX1,FHL1,SRCAP,RAB30,MAP4,MAPT,SERPINE2,PLCD1,PRKAR1B,RIPOR1,RPS6KA2,EMID1,PAQR6,ATXN1,SUPT20H,SYBU,EPN2,KDM4B,EMC1,SPTAN1,ANKRD12,MCF2L,TRIM2,PCDHA6,TK2,ZMYND8,REEP1,NAV2" Drug 6438_UP 5707885; Up 200; 50uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.15E-03 1.00E+00 2.73E-02 3.11E-01 43 186 "APP,CDK10,ASPH,ALDH4A1,BCL2L2,MAP7,CBFA2T2,ARHGEF2,SLC4A7,CRY2,CTH,EDRF1,ANKMY1,PTK2B,SRCAP,RND1,GLRB,FERMT2,GPM6B,FICD,TM6SF1,AFF1,SERPINI1,PLCD1,LRP12,CNNM2,TMEM231,SUGCT,RPS6KA2,ATXN1,SH3BGR,KIF16B,FNDC3A,SPTAN1,SYT1,ASTN2,EXOC7,TRPC1,CLDND1,WNK1,EPM2A,RNF170,RNF146" Drug CID005361912 CTK8G2960 Stitch 5.15E-03 1.00E+00 2.73E-02 3.11E-01 43 186 "APAF1,CACNA1A,CACNA1B,CNR1,HDAC9,NTM,DYNC1I1,ATN1,EGFR,EN2,ENO2,ERBB2,HSPA12B,F3,PPP1R1B,FOXG1,IP6K2,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,HSF2,HSP90AA1,KCNH2,OGG1,PAH,PENK,ABCB1,PACSIN1,PPP5C,QDPR,FBXW7,ATXN7,FOXRED1,HSPA4L,SLC1A3,SNCA,TLR4,HIRA,PRTFDC1,JPH3" Drug CID000004792 phorbol acetate myristate Stitch 5.15E-03 1.00E+00 2.73E-02 3.11E-01 255 1400 "KCNH8,ADCY2,ADCY5,ADCY6,ADCY8,SORCS1,ADORA2A,ADRA1B,ADRB2,KIDINS220,AGT,SORCS2,PLA2G6,CDC42BPA,ANK1,DGKZ,DGKD,APP,PRX,ARHGDIA,EIF4G3,STX16,ADAM15,CFLAR,DST,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,RGN,CD86,SCARB1,DGKI,LRBA,ARHGEF2,CDC42,NOG,CACNA2D2,CHGA,CHGB,CHN1,CHN2,CHRM1,MYL6B,COL4A5,CREB5,AKAP12,CSF1,CSF1R,CSF2RA,VCAN,PLCXD3,CYBB,BOC,EARS2,MAML1,DGKB,DGKG,GSDME,ABI1,EDN1,EDN3,EDNRA,RASGRP1,CACNG7,EGFR,EIF4G1,EIF4G2,TNK2,CALCRL,EPB41,RASGRP2,STX2,EPS8,ERBB2,ERBB4,CDKL3,HSPA12B,F3,RPS6KC1,CACNG2,PTK2B,FCGR1A,FCGR3A,FCGRT,FGF1,ACTL6B,FGFR1,FGR,POLK,FOXM1,FLT1,NELFCD,WDR83,CAMKK2,FYN,GAP43,NEU3,MSTN,GHR,PPARGC1A,MALT1,GJB1,HPGDS,PLCD4,NR3C1,GRM1,IL1RAPL1,TNFAIP8L3,HPSE2,CPT1C,MYLK2,IGF1,IL6R,IL6ST,ITGA7,ITGAM,ITGAV,JAK1,KCNJ4,KIT,STMN1,ASPRV1,MAG,MAP2,MATK,MBP,SYT9,KITLG,MSR1,MYH6,MYL3,MYO6,NCF2,NEUROD1,NF1,NFIA,NODAL,NOS1,NPY,NPPA,NRGN,OLR1,OXTR,P2RY1,PDGFRA,PENK,PFKFB2,PFKFB3,PFKFB4,ABCB1,CAMKV,PIK3C2A,PIK3CD,PIK3R1,PKD1,PKM,PLCB2,PLCD1,TRHDE,MBOAT7,POLG,PPARA,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,PRODH,KLK6,PSMA6,PTAFR,PTHLH,PTH1R,PTK2,PTPRN2,PTPRO,RET,REV3L,GSTCD,RPS6KA2,STX1B,RYR1,RYR3,S100B,SAFB,MAPK12,SMPD3,SELL,HSPA4L,FNDC3A,SLA,SLC1A2,SLC8A1,TMEM132D,SNAP25,SPP1,SST,SSTR2,STX1A,NSFL1C,PLCB1,SYT1,SMG6,CYB561A3,TF,LEFTY2,TGFBR3,TIAM1,TIE1,TJP1,TK2,ICAM5,ACTR6,TNFRSF1B,KAT6B,TNNT1,CABIN1,TPM3,TRH,TSC2,TTPA,UBE2H,GORASP1,BCL2L13,VAV1,VGF,P2RY12,SPHK2,PLPPR5,RGMA,SCG2,PLD4,KAT6A,CAMK1G" Drug CID000023715 D90A Stitch 5.20E-03 1.00E+00 2.76E-02 3.13E-01 23 85 "ALS2,DCTN1,TUBB3,DCTN2,NSG1,INPP5K,DNER,GFAP,GRIA1,GRIA2,GRIA4,GRM3,HSP90AA1,IGF1,NEFM,NEFH,NOS1,PRPH,SLC1A2,HECW1,ZFP91,RTN4,NUP214" Drug 6951_DN "Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.27E-03 1.00E+00 2.79E-02 3.18E-01 42 181 "ARID1A,BCAR3,OGT,CFLAR,ZBED5,NIPBL,GREB1,KIAA0753,ARNT2,DYRK1A,RASGRP1,EGR3,CHST15,AMOTL2,TRAF3IP2,TCERG1,SPIN1,DIDO1,BRINP3,SMAD1,STRN3,RXRA,SCAF8,URGCP,KBTBD4,ERBIN,GSE1,ZC3H4,FAM208A,NSD1,DICER1,TMPO,KAT6B,TRIO,TRPS1,UBTF,NSD2,ZBTB14,ZIC1,ZNF24,PRDM10,ST7" Drug CID000005681 W7 hydrochloride Stitch 5.31E-03 1.00E+00 2.81E-02 3.20E-01 55 250 "ADCY5,ADCY6,ADCY8,ADRA1B,AGT,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,BSN,CACNA1D,CACNA2D1,CACNB2,CALM1,CAMK2B,CAMK2D,CCK,KRIT1,LRBA,CHRM1,MYL6B,CREM,EDN1,EDN3,CAMKK2,ATP2C1,GRB10,HTR2A,MYLK2,KCND3,MTTP,MYL3,NOS1,PDE1C,PDE1B,CAMKV,PPP1R1A,PTPA,PPP3CA,PPP3CC,PRKACB,PRKCB,PRKCG,MAPK3,KCNIP2,RYR1,RYR3,PLCB1,SYN2,CABIN1,BCL2L13,RNF103,PLD4,CAMK1G" Drug CID000004421 nalidixic acid Stitch 5.32E-03 1.00E+00 2.82E-02 3.21E-01 60 277 "SLC12A5,SLC24A4,AGT,MRTFA,ANK2,ANK3,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP2A2,INA,CBFA2T2,SCARB1,CHN1,CLU,SLC24A2,SUMF2,SLC4A8,PLCXD3,DCT,EDN1,EDN3,EDNRA,EDNRB,TAOK3,ZMYND10,AFF2,NKX6-2,PLCD4,HNRNPK,MAT2A,MID1,MTR,NBL1,NOVA2,NPPA,ENPP2,NALCN,PLCB2,PLCD1,FXYD1,OXR1,RYR1,SCNN1D,SLC6A7,SLC8A2,SLC8A1,SLC8A3,SLC9A5,SLC12A2,SLC12A4,SLC14A1,SLC20A2,PLCB1,NPL,WNK1,WNK3,FXR1,ST8SIA2" Drug CID000125085 NAPs Stitch 5.35E-03 1.00E+00 2.84E-02 3.23E-01 17 57 "CNR1,ABCG1,WDR20,DRD1,ST6GALNAC3,HRASLS5,NCKAP1,MALT1,NAP1L1,NAP1L3,MRAS,SNAP25,SOX10,NPL,TST,PLD4,HRASLS" Drug CID000095575 DL-propargylglycine Stitch 5.37E-03 1.00E+00 2.84E-02 3.23E-01 15 48 "NFS1,CBS,KYAT1,CDO1,CTH,CDON,PNMA2,GPT2,MATN3,MTR,OGDH,APTX,SYT1,TAC1,TACR1" Drug CID000100771 NSC364150 Stitch 5.37E-03 1.00E+00 2.84E-02 3.23E-01 15 48 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GAD2,MSTN,TNFAIP8L3,NODAL,MAPK8,MAPK9,MAPK10,SYT1,SYNE1" Drug CID009929833 tryprostatin A Stitch 5.37E-03 1.00E+00 2.84E-02 3.23E-01 15 48 "SERPINA3,DYNLL1,CHGA,TUBD1,ENO2,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,NOVA2,ABCC8,TUBB1,TUBA1A,WIPF2" Drug CID000002727 chlorpropamide Stitch 5.37E-03 1.00E+00 2.84E-02 3.23E-01 15 48 "SERPINA3,ABHD6,ANK1,ALDH7A1,SLC22A6,CHRDL1,AASDH,GCK,HBA1,NBL1,NEUROD1,PENK,SPTB,ABCC8,TCF7" Drug 7525_UP daunorubicin HCl; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.39E-03 1.00E+00 2.84E-02 3.23E-01 41 176 "ANK1,APC,PPFIA3,CAPRIN2,CFLAR,BMP7,BTRC,HAP1,CAMK2G,RCBTB2,TPP1,WHRN,DAPK3,TMCC2,EN2,FGFR3,BAIAP2,SYT17,SESN1,GLS,GRIN2C,IL6R,INPP1,NPTX1,PDE4A,SERPINI1,PPP5C,RALGDS,GSTCD,ROM1,PAQR6,ASAP3,PEX26,SLC6A8,INKA2,MAPK8IP3,ARC,ZMAT3,ZNF34,ZKSCAN5,PDIA2" Drug CID000447082 1m5d Stitch 5.40E-03 1.00E+00 2.84E-02 3.23E-01 12 35 "AMH,RGN,GDA,TUBA1B,GRIA2,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HSP90AA1" Drug CID000123756 mantATP Stitch 5.40E-03 1.00E+00 2.84E-02 3.23E-01 12 35 "MYH7B,APAF1,DNAH9,CASP8AP2,DDX19B,KIFC3,MYO5A,PFKFB2,PFKFB3,PFKFB4,ABCB1,GSTCD" Drug CID000005723 zardaverine Stitch 5.40E-03 1.00E+00 2.84E-02 3.23E-01 12 35 "ADCY5,ADCY6,ADCY8,ALDH7A1,CDH2,MTR,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,TJP1" Drug 1441_UP Mafenide hydrochloride [138-37-4]; Up 200; 18uM; HL60; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "BRAP,APAF1,EIF4G3,MTMR2,WASF1,KRIT1,RCBTB2,SRSF11,NIPBL,OSBPL3,FBXL5,RCAN1,SUGP2,EGR3,KCTD3,ANKMY1,ACSL4,FECH,KIAA1109,ATP2C1,HBS1L,ERAP1,GLS,MUM1,MBNL1,PCMT1,PDE3B,LRP12,C1orf109,TMEM156,ATXN7,RAB3GAP1,CCDC88A,KBTBD4,ELMO2,MAPKBP1,CDK19,SAMSN1,SS18,ARHGEF12,PUM2,TSN,HIRA,FLRT2,NSD2" Drug 6169_DN alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABAT,ADD2,APP,SEMA4G,CASK,BMP7,SCAPER,CAPN3,TAOK2,CLCN4,CPS1,CLOCK,PPP1R16B,ARHGAP32,TBC1D5,KIAA0753,ABI2,BSCL2,FHL1,SEMA4D,CAMKK2,COPS8,ATXN2L,JAK2,KIF2A,SMAD1,OGG1,MAPK8,TMEM231,MRPS18A,RNASEL,FOXRED2,SBF1,ITSN1,ST6GAL1,WDTC1,ZC4H2,TCF7L2,PSD3,CABIN1,RBFOX2,TRPS1,FLRT2,NT5M,GDPD5" Drug 2428_UP Biotin [58-85-5]; Up 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG3,ADORA1,BEGAIN,ALDH4A1,SGCE,CACNA1I,ASIC3,SLIT2,CNTN1,CSF1,PDE4DIP,E2F5,EFNA3,EIF1,ETV1,DCTN2,TRAF3IP2,RUNDC3A,RND1,GPR22,LAMA2,SLCO1C1,OCRL,PDE4A,PDE4D,CAMKV,SPATA6,PPARA,PTPRN2,SEC61A2,MYH14,FBXW7,FRMPD1,PREX2,BTBD7,SS18,SEPT8,WSCD1,PCDHGB6,TGFBR3,UGT8,SLC13A3,SLC17A6,FZD3,ST7" Drug 4604_DN Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABR,ASIC1,BIN1,APOC1,PPFIA3,ARRB2,ADAM15,MAP7,SLIT2,HOMER3,CTNND2,KIAA0513,DBT,RUSC2,SGSM2,FEM1B,PLEKHO1,EPHA5,GCNT2,ZNF276,POLL,PRRC2B,NR3C1,DHX35,SHISAL1,SCIN,NASP,NDP,OPCML,PLEC,RC3H2,PEX5,PID1,SBF1,SLC20A2,STX1A,ARHGEF9,EXOC7,KIAA0930,TRIM2,TK2,UBTF,NSD2,MAP3K12,AAAS" Drug 575_UP copper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADRB2,APAF1,APBA2,AQP6,PDXK,PLA2G4C,ARSF,CAPRIN2,NRP2,HAP1,CDH2,DLGAP1,ARHGEF10,FEM1B,SORBS3,KIAA1109,OLFM1,PRKAG2,POMT1,SYT17,SEPT9,FERMT2,GRIN1,GRM8,FAM107A,RNFT2,IRF8,MID1,ADAM22,MSR1,NPR2,P2RY1,SNTG1,PLCD1,PTPRD,PYGM,PLEKHB2,RNASE1,SYNDIG1,ZCCHC24,SPART,TBL1X,TMPO,TPM3,ZKSCAN5" Drug 375_DN tamoxifen citrate; Down 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG2,C1QTNF1,AMPD2,APC,CDK10,ASCL1,CADM3,DLGAP1,CHGB,IFFO1,CSF1R,GREB1,DAPK1,SRGAP3,E2F5,EFNB3,EGR3,STX2,FECH,FOLR2,PDLIM5,NSG2,FYN,GAB1,GAD2,B4GALNT1,GRIN1,BTN2A1,KCNJ10,OPCML,GPR173,RGS12,DCUN1D2,TCP11L1,GALNT10,KDM4B,EMC1,STX1A,VAMP1,KAZN,SZT2,TNR,SEZ6L,WIPF1,MPPE1" Drug 2473_DN Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APBB2,APC,NCOA1,ATP2A2,ARHGEF7,CAMK2G,FOXN3,CLCN4,IQCK,ABCG1,DBT,ZNF804A,DTNA,TUBD1,LRRC23,VPS26C,FYB1,ZMYND11,GALC,INPP5K,DIDO1,ITGAM,IPO5,SCAMP5,CNOT4,OCRL,PILRA,CNNM2,SIDT1,RAB3A,RAB3IL1,SEC14L1,EPN2,SLC11A1,BTBD7,EMC1,TROVE2,SS18,ATP11A,TACC1,ADGRL3,KIAA1107,SZT2,TLR4,PHTF2" Drug 5400_DN S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "RALGAPA1,ASPHD1,APOC1,APP,CACNB2,TAOK2,ENTPD4,DBN1,ZNF804A,SGSM2,DTNA,OPTN,EFNA3,MBNL2,KAT8,ZNF589,OGA,GALC,INPP5K,GCNT2,AHDC1,GPER1,GRIK5,MPP2,LYRM9,NF1,OGG1,PDE3B,NLE1,MINDY2,PRODH,RAB3IL1,MSANTD2,RGS12,FOXRED2,SBF1,CLSTN2,THSD1,PLCB1,CRTC1,AHCYL2,TK2,UPF3A,SEMA3B,EPM2A" Drug 7150_DN "(+,-)-Synephrine [94-07-5]; Down 200; 24uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APBB2,APP,MPDZ,BCL2L2,CHM,AKAP7,FAM169A,EDIL3,EGFR,EIF5,STX2,ST3GAL6,ZNF589,ANKFY1,EFCAB2,INPP5K,GLUL,GNAS,IFI16,DIPK1A,MKLN1,CNOT4,SETD4,CCSER2,PRKACB,TMEM104,PID1,ROGDI,HSPA4L,PPP1R9A,SHMT2,SLC1A3,ZKSCAN3,DOP1A,TTBK2,KIAA0930,TRIM2,ARHGEF12,AHCYL2,PLPPR2,KLC2,FZD3,PHTF2,ACTR3B,AAAS" Drug 1333_UP "Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABAT,ADD1,MTUS1,DOC2A,ANK3,APBB2,CDK10,SYNJ1,LARGE1,RAB33A,TMEM184B,IQCK,IFFO1,VCAN,SMG7,SIDT2,LRRC23,FER,GAD2,ADAM28,GLYR1,ATXN2L,ARHGAP12,OGG1,PDE3B,PMP22,MAPK8,PEX5,CEP97,RAD52,ZNF671,PLPPR3,RASA3,FUZ,BTBD7,DBNDD2,FAM168A,KIAA1107,TCF4,SIN3B,PIK3R5,ZNF384,BEST1,TFIP11,ST7" Drug 1113_UP doxycycline; Up 200; 14.4uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABR,OSBPL1A,APP,NUMB,ATM,EIF4G3,BMP7,RAB29,MICAL2,USP6NL,TM9SF4,RASGRP1,SH3GLB1,PHF20L1,EGR3,EFCAB2,SMC2,MPP6,SEPT9,FICD,SLC2A6,MAP4,NEK1,NRGN,PBX1,PC,GON4L,PLEKHB2,SEC61A2,DCUN1D2,MAP6D1,PAQR6,ATXN1,URGCP,PEX26,KDM4B,NSFL1C,KLHL7,ANKRD12,KAT6B,HIRA,ZBTB14,TFIP11,HPS4,JMJD1C" Drug 6725_UP (S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AGT,ALK,APAF1,CDK13,SLC4A4,CFAP410,CBLN1,MAGI1,CHRNA4,EPS15L1,CNTFR,CRY2,SUSD5,CTNND2,TBC1D5,SPOCK2,SRGAP3,FGF1,FGFR1,TRMO,OGA,GPR75,IL12A,LAMA2,MT1M,TAGLN3,ENPP2,DUSP26,SPATA6,PPP5C,GON4L,RAB3IL1,CCDC40,ENOX1,CNKSR2,PREX2,ZNF334,IQSEC2,CDK19,NPAS3,AP4E1,TNFRSF1B,TRPC1,VAV1,PARP11" Drug 3000_UP Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABAT,NR0B1,BIN1,MYRF,CHGB,HOMER3,NRG2,HAPLN1,NCOR2,SUSD5,ARNT2,EXOG,EGFR,EPHB1,INPP5K,NEU3,GPD1,GUCY1A2,SCIN,KIF5A,MBNL1,MMP16,ADAM22,MYCN,NTRK3,CCDC40,BEND5,GAL3ST4,PNMA8A,SELL,RIMS1,DOP1A,PEG10,LHPP,NSFL1C,SMG6,FAM189A1,ATP13A2,ZFPM2,TPM2,FLRT2,WNT7A,KLC2,FZD3,SSPN" Drug 2389_DN Trifluoperazine dihydrochloride [440-17-5]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ALK,PPFIA1,N4BP2L1,BCL7A,CAPN3,SOCS6,ZNF337,CTIF,FHL1,ANKFY1,COPS8,GRB10,JAK2,MAP4,NFYA,CNOT4,OGG1,CCSER2,PLCB2,PTPA,PTAFR,FAM184A,TMEM156,ITSN1,FNDC3A,URGCP,PPP4R3A,RAB3GAP1,ZNF667,KDM4B,EMC1,ZBTB43,FCHO1,ATP11A,TCF7L2,SLC44A1,THRA,PIK3R5,RBFOX2,PLPPR2,NSD2,ZBTB14,MPPE1,ST7,AAAS" Drug 5616_DN Enoxacin [74011-58-8]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,GAS7,BCAS1,GYG2,CFAP410,CBFA2T2,TPP1,HOMER3,AKAP7,ABI3BP,SH2B1,CSNK1E,PDE4DIP,MED12,DRD1,RCAN1,EFNA3,SORBS3,ING4,MRNIP,CAMSAP1,GAA,GABRA2,NR3C1,RASSF8,ICA1,CNOT4,NPTX1,SETD4,PRODH,RPS6KA2,AMBRA1,SLC1A7,BTBD7,KDM4B,ARHGAP26,ELOVL4,ATP11A,DMXL2,KIAA0930,TCF7L2,TNS2,CABIN1,WNK1,HPS4" Drug 2695_DN genistein; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG2,BRAP,AMT,APAF1,ADAM23,CAMK2G,MAP7,CLCN4,HOMER3,CSF1,SLITRK5,HDAC9,MAML1,DTNA,PCOLCE2,ELN,COQ7,ANKMY1,CAP2,AFF2,CAMKK2,GATM,ZNF276,GNG4,GPD2,IRF8,ITGA7,LSS,MAP4,MATK,MEST,CNOT4,PDE4A,POLG,BCAS3,PTCH1,RET,WDTC1,DDN,KANK1,GSE1,PLCB1,KAZN,TCF7L2,TNS1" Drug 4164_DN Thioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AK2,LTBP4,APLP1,ALDH7A1,SYNJ1,BTRC,CAMK2B,LHX2,ZFYVE9,DNAJB5,QKI,SNCAIP,MICAL2,PHF14,PARD6A,TMCC2,HIPK3,ING4,ZNF589,FGFR3,DPYSL4,GLYR1,GNG4,GPER1,INPP5B,KCNK2,KHK,ADAM22,NASP,NUMA1,LRP12,MINDY2,PRKAR1B,MAPK10,RAD52,RGS10,CCDC25,SNCA,EMC1,THSD1,DICER1,TRPM2,UCHL1,SSPN,SENP7" Drug 5238_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "PLA2G6,EPB41L5,SEMA4G,PDE8B,BRINP2,ATM,CFLAR,BMP7,GYG2,BTRC,CAMK2G,FOXN3,SLIT2,ZFYVE9,PDE4DIP,EFNA3,EGFR,STX2,DISC1,INPP5K,GFER,GPM6B,STON1,GPR37,LSS,SLC11A2,LRP12,MBOAT7,POLG,RIPOR1,PPP1R9A,ASAP3,SLC6A8,LIMCH1,SNCA,WDTC1,ZBTB43,POPDC3,TBL1X,PSD3,LMF1,KLC2,SPHK2,REEP1,GDPD5" Drug 2329_DN Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABHD6,APC,CDK13,MARK4,ATM,CFLAR,SYNJ2,CBFA2T2,RCBTB2,HOMER3,SLC4A7,BAG4,CSF1,EDRF1,DCAF8,RIMS3,DTNA,TSPAN5,EFNB3,C3orf18,DMTN,FGFR1,FOXG1,FAM49B,GLYR1,MSL3,GSTM5,IL6ST,KCNJ3,KCNN2,MPP2,NF1,CNOT4,NTRK2,PCDH9,CDK14,STRN3,RAB3A,RAD52,POGZ,TCF7,FLRT2,SYNC,EMSY,KCNAB1" Drug 5600_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABAT,MTUS1,MRTFA,BIN1,EPB41L5,GAS7,APLP1,APOC1,BRINP2,CACNA1I,CDC42,RCBTB2,STOML1,CNTNAP2,SMG7,ATN1,EFNB3,TNK2,DLC1,FHL1,PRELID3A,GABRA2,GPM6B,GRK4,GSN,GSTM5,ITIH2,KCNMA1,MDM4,ADAM22,SLC11A2,PFKFB2,ZCWPW1,ZFHX4,EMID1,SBF1,PPP1R9A,PREX2,SMARCD3,SMG6,ARHGEF12,LMF1,SEMA3B,PCBP4,EPM2A" Drug 6999_DN 2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP2A2,CDC42BPA,APBB2,CDK10,CDK13,CFLAR,AP4M1,HOMER3,FEZ1,MICAL2,DCAF8,DAPK3,MFAP3L,DTNA,FEM1B,RGS17,KAT8,FOXG1,FAM49B,CGREF1,GALC,TXNL4A,GNG4,GRB10,KCNJ3,KITLG,STRN3,POLG,PPP2R2B,PPP5C,RIC8B,SLC15A2,ELMO2,SLC20A2,MAPKBP1,ZHX3,EXOC7,TCF7L2,WASHC4,CABIN1,RBFOX2,UBTF,VGF,VIPR2,ZBTB38" Drug 4477_DN 6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADRA1D,PLA2G6,APOC1,CDK10,ALDH7A1,BCL7A,SCAPER,BTRC,ARHGAP33,CACNA2D2,ASIC3,CLCN4,LY86,AATK,RUSC2,RABGAP1L,FEM1B,SORBS3,ING4,KIAA1109,MSL3,KCNMB4,DIDO1,AGFG1,IL6ST,KPNA5,MEF2C,SCAMP5,PBX1,SLC25A23,POU3F2,GRAMD1C,RAB3A,SH3GL2,SLC9A5,BTBD7,WDTC1,IQSEC2,MAPK8IP3,AHCYL2,TEX15,TRPC1,CADM1,SF1,SEMA3B" Drug 4988_DN Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,AK2,APC,PPFIA3,KYAT1,MAGI1,FOXN3,B4GALT6,EPS15L1,QKI,ENTPD4,PDE4DIP,HDAC4,INTS1,ZNF804A,PARD6A,DLG3,TRAPPC9,DTNA,MBNL2,EML1,ACSL4,FER,TRAF3IP2,SEPT9,INPP5K,CRCP,PADI2,MBD1,PMS2,RAB5B,ROM1,SHANK2,KDM4B,KDM4C,GANAB,FAM168A,ANKRD12,IQCE,TRIM2,KCTD2,ZMYND8,PLPPR2,HPS4,SMIM8" Drug 3242_UP Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABHD6,NDRG2,ADORA1,SEMA6A,SPOP,TRMT9B,AMH,BIN1,ARHGDIG,ASPH,ATP6V0A1,NEURL1,TAOK2,QKI,ENTPD4,EDRF1,DTNA,MBNL2,EPB41L2,DMTN,LRRC23,GLYR1,KLF12,ICA1,LMO2,MAN2A2,MDM4,MMP16,ZNF862,PALM,PLCD1,NECAB2,MED1,MAPK7,RPS6KA2,FAM214B,DOP1A,ZNF423,WSCD1,TMOD1,UPF3A,EVI5,MVB12B,KAT6A,PHTF2" Drug 1870_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APP,ZSCAN18,NCOA1,ATM,CFLAR,ST3GAL5,SYNJ2,CAPN3,SCARB1,SRSF11,FOXN3,QKI,CREM,DBT,TOM1,HIPK3,TNK2,COQ7,IGSF6,PTK2B,SCML2,ZNF589,GLYR1,LILRB4,CACFD1,MAP4,OCRL,PDE3B,GPR85,SERPINE2,TNPO2,PTPA,PPP3CB,C12orf49,DGLUCY,FERMT1,SEC31A,EXOC7,RBFOX2,TST,XRCC4,ZNF32,TFIP11,NT5M,EPM2A" Drug 4588_DN Vitexin [3681-93-4]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,ATP1A3,NRP2,SCAPER,SYNGR3,DNAJB5,WHRN,PPP6R2,CDON,DTNA,DUSP9,EDIL3,CELSR3,DMTN,ETV1,OGA,GPM6A,GRIK2,ELOVL5,SYNPO,MDFI,NDUFA5,CNOT4,SLC11A2,CLDN11,STRN3,FA2H,PRPH,ZSCAN32,FAM120C,IL17RB,ZNF821,AMBRA1,PDZD2,CAND2,LHPP,POGZ,SAMSN1,TCF4,CHST8,TNS1,VGF,XRCC4,SMIM8,PHTF2" Drug 4975_DN Fursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ATM,KIF1A,SCARB1,LRRFIP1,VAX2,AKAP7,SLC4A8,JAKMIP2,MFAP3L,TRAPPC9,RCAN1,MRNIP,EPB41L1,F3,FGFR1,CGREF1,GPR19,HSD17B1,MBD1,MPP2,NFYA,NPR2,NRGN,NUMA1,PBX1,PLXNB1,PPP2R5C,PRODH,PTHLH,RAB3A,CEP97,RAD51D,RXRA,ZNF821,SYBU,PEX26,FAM214B,LHPP,THSD1,RPGRIP1L,PSD3,TRIO,UBE3A,UBTF,REEP1" Drug 5541_UP Mometasone furoate [83919-23-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADCY6,ADD2,ADORA1,CNTNAP1,APP,CDC14B,SEMA4G,CHRD,ATP6V0A1,BTRC,USP2,CLGN,QKI,DTNA,FGFR1,IQCG,GAD2,GATM,RND1,GNG3,GPM6B,NR3C1,HNMT,JAK2,KCNH2,KCNK1,LIG4,TAGLN3,NF1,LRP12,MAPK8,SNRK,PTPRD,TMEM231,MRAS,SH3BP2,FRMPD1,SYBU,RPH3A,EFHD1,KIF13A,SSTR2,VAMP1,MCF2L,CHST5" Drug 7454_UP Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "EPB41L5,APOC1,ALDH4A1,SGCE,CAMK2B,USP2,SLIT2,ZFYVE9,FAM189A2,CSNK1E,SIPA1L1,CYBB,CTIF,GIT2,OPTN,MRNIP,PDLIM5,OGA,C1QL1,TDRKH,GPR19,CNTRL,RNFT2,KCNJ5,KCNN1,MDM4,LYRM9,NEK1,NF1,PDE3B,PIK3CD,PLXNB1,MBOAT7,MINDY2,LRRC49,TRIM68,SH3GL3,SLC1A7,ARHGEF40,WDTC1,RGL1,TRIM2,PCDHA6,TIAM1,NUP214" Drug 4800_UP Minoxidil [38304-91-5]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ASIC1,ACTN2,CDC14B,PTCH2,SLC2A11,MTMR2,LDLRAD4,BTRC,SOCS6,CLCN4,CHD1L,NECTIN3,CSF1R,CNTNAP2,CTNND1,RIMS3,DBN1,FCF1,RGS17,KAT8,OLFM1,AGAP2,SYNPO,HPCA,DIPK1A,KCNH2,KCNMA1,VWA5A,KITLG,NF1,TCP11L1,SH3GL3,LIMS2,SMARCD3,SNCA,ZC3H13,NXT2,PSD3,SEZ6L,SSBP2,LAT2,CLDND1,UPF3A,PLSCR4,RNF146" Drug 4658_DN Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP1B1,NME5,MYRF,B4GALT6,CLCN4,BAG4,CPS1,ARHGEF10,ARHGEF4,SIRPA,CNIH3,KIAA0753,SMG7,EFNB3,IRAK4,ING4,SCML2,ATP8A1,SORBS1,FYN,DENND2A,GPD2,CNTRL,SHISAL1,DIPK1A,MEIS1,MITF,MN1,PPARA,PRKAR1B,TMEM231,SH3TC2,ATG16L1,RGS10,SEC61A2,MCMBP,ZNF821,FUZ,ST6GAL1,ARHGAP26,THSD1,CEP68,AHCYL2,SSBP2,WIPF1" Drug 7350_DN Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP2A2,AMPD2,BCAS1,PPFIA3,APP,CFLAR,C5,TAOK2,SLC4A8,CSNK1E,CTH,EDRF1,LYPD1,DTNA,FCF1,ITPKB,KCNH2,LIG4,MATK,KITLG,MITF,NCAM2,NFYA,PLEC,PRKAR1B,MAPK8,RAB3IL1,CEP97,GSTCD,NEK11,ATXN2,ZKSCAN3,WDTC1,CLASP2,FCHO1,ATP11A,EXOC7,VIPR2,ZBTB14,DNALI1,GDPD5,KCNAB1,MPPE1,UBE3B,AAAS" Drug 6952_DN genistein; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AK2,ANK3,PPFIA3,MARK4,RIPK1,MPDZ,BCL7A,CFLAR,C5,LHX2,HOMER3,COL9A2,CREM,CRY2,HINFP,LYPD1,SIDT2,MRNIP,CDKL3,VPS26C,FHL1,GPR153,GART,ZNF276,HTATSF1,POLL,GPR37,CNTRL,GRM8,ATXN2L,HSF2,KHK,MGAT3,NEK1,NF1,SLC11A2,PCDH9,SLC25A23,SAMD9,RGS3,SLC15A2,SEMA4A,IQCE,TCF7L2,SSPN" Drug 1055_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABAT,ASPHD1,ANK3,NUMB,ATM,RAB26,PPP6R2,TBC1D5,GIT2,DSCAM,USPL1,STX2,VPS26C,KAT8,B4GALNT1,ZNF276,KCNMB4,GPR19,NUDT21,GRB10,IL6ST,KCNJ3,MAP4,MPP2,N6AMT1,NCAM2,NEK1,NF1,PPP5C,MAPK3,FBXW7,TCP11L1,ATXN1,SUPT20H,ZNF430,SP2,ZBTB43,CAMTA2,SS18,NXT2,ELOVL4,NSFL1C,TBL1X,TCF7L2,ZBTB14" Drug 7093_UP 0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APLP1,CA12,LRRFIP1,NMT2,WHRN,MICAL2,NOS1AP,DOCK4,RIMS3,SGSM2,DTNA,SUGP2,MRNIP,DENND4A,F3,KIAA1109,ATP2C1,GPR153,NR3C1,BTN2A1,IL6ST,KCNJ3,NEK1,PLCD1,MAPK7,CNNM2,FAM120C,RGS10,RNASEL,ROM1,ZNF821,SUPT20H,SYBU,KDM4B,ZHX3,ZBTB43,POGZ,SS18,VPS13A,TMOD1,LMF1,XRCC4,ZNF74,GDPD5,EPM2A" Drug 4009_DN Sulmazole [73384-60-8]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,GAS7,APP,PDE8B,ATP2A2,ALDH7A1,SYNJ2,BTRC,HOMER3,RUSC2,CDON,ATN1,CNNM1,MRNIP,EPB41L1,COQ7,ETV1,GRM8,SHISAL1,LIFR,LMO2,MBD1,NDP,NUCB1,PDE4D,PLCD1,PPP5C,KHDRBS2,RGS4,RGS10,MYH14,AMBRA1,FNDC3A,SLC6A9,ARHGEF40,SLC9A5,SS18,ELOVL4,SYT11,ARC,RPGRIP1L,SYNE1,DNAH7,CABIN1,NT5M" Drug 2194_UP Beta-Escin [11072-93-8]; Up 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "BEGAIN,BIN1,SEMA7A,ASCL1,DNAH17,MYOM1,USP2,CDH2,MAGI1,CNTN1,CREM,DAPK3,EFS,BAIAP2,C1orf61,SEMA4D,TACC2,NEU3,ALDH1L1,GFAP,GLRB,PCSK1N,KCND3,MBP,MX1,NTRK2,CLDN11,PDE4A,PTN,PTPRB,MORC4,MYH14,CPEB3,PKNOX2,CXXC4,SNCA,TROVE2,PHLDB1,VAMP1,RALYL,AP4E1,LMF1,ZIC3,KCNAB1,PLSCR4" Drug 7529_UP Suramin sodium salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADCY6,SEMA4G,ALDH4A1,BTRC,KYAT1,SCARB1,PICK1,CHD1L,CREM,KBTBD11,CNNM1,EGFR,CDKL3,F3,ZNF589,BAIAP2,PDLIM5,POLL,BTN2A1,SCIN,KCNJ5,LIG4,MIA2,MPP2,NFYA,PCDHGC3,EPN1,TNPO2,KCTD17,SIRT2,BTBD7,ARFGAP1,CDK5RAP2,FNBP1,KDM4C,LHPP,TROVE2,MAPK8IP3,DIP2A,COBL,AHCYL2,GPR161,EVI5,EPM2A,SMIM8" Drug 6103_DN Podophyllotoxin [518-28-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,TRMT9B,AMPH,CADM3,ADAM23,CA12,CACNA1D,KYAT1,NEURL1,FOXN3,PICK1,CRMP1,HIPK3,PLXNC1,ING4,FGFR1,C1orf61,MSL3,GNAS,KCNF1,LSS,MAP4,TM6SF1,GIT1,ADAM22,NPTX1,NUMA1,PDE4B,PLCD1,LRP12,MAPK7,RAB3A,RAD52,RALGDS,RGS3,GSTCD,ZNF821,KIF13A,SOX2,PCDHA6,TGFBR3,CABIN1,CADM1,VIPR2,NT5M" Drug 6416_UP PF-00539758-00 [351321-34-1]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADGRF5,SPARCL1,CDK13,ADGRB2,ARHGEF6,CRMP1,TENM4,VCAN,MFAP3L,NTM,EGFR,SPEG,NSG1,FYN,GAB1,POLL,NR3C1,CELF3,IL12A,INPP5B,ADAM22,PDE4D,CDK14,SERPINE2,PLCD1,GDPD2,ZFHX4,HUNK,KCNIP1,RYR1,SLC12A4,SNCA,HECW1,SPTAN1,JMJD6,VAMP1,HIF3A,THBS4,TRIO,FAM155A,OSBP2,TRIM9,MVB12B,FAM13C,SSPN" Drug 1684_DN "Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP2A2,CDC42BPA,ANK3,FAM131A,CDK10,DNAH17,ALDH4A1,KIF1A,BCL7A,GYG2,BTRC,CA12,CCNT1,SCARB1,CSF1R,PDE4DIP,PPP6R2,DAPK3,TRAPPC9,ATN1,OGA,DISC1,USP19,MSL3,GNAS,DHX35,SLC11A2,PDE3B,PDPK1,STRN3,MBOAT7,MAPK7,MAPK8,RAB3A,RAB3IL1,FAM184A,ZNF821,AMBRA1,BTBD7,WDTC1,ZBTB43,TROVE2,PLPPR2,MICAL1,HPS4" Drug 2024_UP Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; HL60; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADD1,APOC1,AQP6,ARRB2,ASPH,N4BP2L1,RAB29,SLC25A14,CAST,NEURL1,CHGB,CHN2,FAM189A2,AKAP7,CREM,ECE2,MAML1,DCT,ABI2,RASGRP2,KAT8,MALT1,GLUL,OS9,PCSK1N,GNG4,LILRA2,GPR12,IL6R,MAP4,MYT1,SETD4,PALM,PC,PIK3R1,CCDC25,FAM102A,KBTBD4,ELMO2,IQSEC2,SS18,SYN2,KAT6B,UPF3A,NT5M" Drug 2545_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "MRTFA,CDC42BPA,APC,N4BP2L1,ADAM23,CAST,HIP1R,EPS15L1,RCHY1,SV2A,SLC12A6,MRNIP,CAP2,PDLIM5,CSPG5,ERAP1,GRM1,NCKAP1L,ATXN2L,VWA5A,MEF2C,NF1,NPR2,CCSER2,PLEC,PRKAB2,SIDT1,CEP97,CNKSR2,SLC12A2,ZKSCAN3,WDTC1,KDM4C,DBNDD2,CDK19,TROVE2,LARP4,WWC1,TCF7L2,PARD3,TNNT1,TPM1,HIRA,PRDM2,EVI5" Drug 7462_DN DO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "MARCH3,SLC25A14,LHX2,HOMER3,CTNND2,PPP6R2,EDRF1,HDAC4,KIAA0586,GIT2,DBN1,C2CD2L,LYPD1,PARD6A,CAMSAP1,GRB10,DIDO1,NR3C1,PADI2,IDH3B,KCNF1,IPO5,MEIS1,MITF,NACA,NFYA,OXTR,KCTD15,PLEC,PPP5C,RALGDS,SLC15A2,ARFGAP1,RCOR3,PDZRN3,ZBTB43,SPART,FAM168A,ARHGEF9,TACC1,ZNF24,ZNF32,MAP3K12,EMSY,SMIM8" Drug 1363_UP Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "BRAP,ATM,ATP2B1,BACH1,CAST,KRIT1,CBFA2T2,SRSF11,CREM,FEZ1,SOCS5,PPP1R16B,CX3CR1,GIT2,SGSM2,ERCC2,VPS26C,ATP2C1,MPP6,INPP5K,NR3C1,GSTM5,IPO5,KTN1,MAP4,NAP1L1,NTRK3,ENPP2,SNX10,RETREG1,ST8SIA5,TRHDE,POLG,PPM1B,ZC3H14,ELMO2,SLC22A4,ZSWIM8,TSPYL2,PHLDB1,VAMP1,FBXW11,TCF4,WRN,JMJD1C" Drug 1485_DN Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG3,ARRB1,CDK13,SMARCAL1,ARHGEF10,SMG7,DSCAM,RCAN1,EFNB3,SORBS3,ANKMY1,SEMA4D,SRCAP,USP19,TDRKH,ARHGAP19,IL6ST,MAP4,MITF,MSRA,SLC11A2,LRP12,PPP2R2B,PRPH,TMEM104,WDR25,RAD51D,RNASEL,FBXW7,ITSN1,BTBD7,SMARCD3,WDTC1,EMC1,ZNF423,NCDN,PLCB1,ATP11A,ANKRD12,EHBP1,TRIM2,PARD3,RBFOX2,TRPC1,TFIP11" Drug 2374_UP Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "C1QTNF1,BIN1,ANK3,APP,PRX,ARRB1,ZSCAN18,RUNX1T1,USP2,LARGE1,PDE4DIP,ZNF337,RIMS3,PARD6A,NTM,DTNA,EFNB3,LRRC23,GPR162,KLF12,ICA1,IL11RA,MMP16,NAP1L2,NEK1,NUMA1,PDE1C,PDE4D,CCSER2,GALNT10,SH3BGR,RPH3A,PEX26,SLC9A5,SLC20A2,ZCCHC24,RBM26,SYP,KAZN,WSCD1,NSD1,CRTC1,FLRT1,TRIM9,EMSY" Drug 1506_UP Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "DPF1,RALGAPA1,ADGRF5,SEMA6A,ALCAM,SEMA7A,APOC1,ATP2B2,SYNJ1,SYNJ2,SCAPER,CACNA1I,CAMK2B,ARHGEF1,QKI,CSF1R,RIMS3,KLHL3,DRD1,DSCAM,EFNB3,EFS,HPCAL4,FOXG1,FOLR2,TRAF3IP2,GAD2,GRK4,NR3C1,HLF,MYO7A,ZNF862,SLCO1C1,NPR2,PDE3B,PDZRN4,MINDY2,PPP2R2B,ZDHHC14,EMID1,SLA,SLC1A2,TCF7L2,TEX15,ZNF45" Drug 4714_DN PNU-0251126 [267429-19-6]; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APC,APP,NCOA1,ARHGEF2,ADGRG1,SOCS6,CLU,PDE4DIP,BRINP1,JAKMIP2,ZNF804A,ATN1,DTNA,HSD17B14,ENO2,SCML2,ST3GAL6,ZNF589,FYB1,SEPT9,INPP5K,GART,GRM8,HNMT,HSF2,KPNA5,MPP2,NEUROD1,LRP12,SAMD9,ZSCAN32,RAB3IL1,RGS10,PEX26,SPTAN1,TROVE2,NXT2,MAPK8IP3,ZEB1,PSD3,THRA,TRIO,FAM155A,EVI5,TIGD6" Drug 6310_UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABHD6,ARID1A,PLA2G6,CFLAR,SYNJ2,SCAPER,CACNA1I,RUNX1T1,ARHGEF1,IFFO1,PDE4DIP,CTIF,EXOG,EDIL3,EFNA3,EFNB3,EGFR,IRAK4,STX2,RRAGB,FOXG1,PNMA2,GART,ATXN2L,KLF12,HNMT,IDH3A,KCNK1,LIG4,MAN2A2,NNAT,CNOT4,ZFYVE21,CNTLN,CCDC88A,SLN,TAB2,ATP10B,MAPK8IP3,ARHGEF12,DNAH7,BEX4,LAT2,SH3GLB2,NT5M" Drug 2052_DN Diazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ACLY,BIN1,ARRB2,MTMR9,CFLAR,ST3GAL5,MAP7,RAB28,WHRN,CHD1L,SH2B1,CSNK1E,VCAN,ARHGEF4,TBC1D5,GIT2,SPATA2,PARD6A,SGSM2,TMCC2,TRAPPC9,LPAR6,EPB41L1,WAC,DENND2A,HBS1L,GLUL,GPD2,EML4,HNMT,INPP5B,ARHGAP12,MAP4,ZNF862,PLCD1,LRP12,MED1,SH3BP2,ASAP3,BTBD7,WWC1,TRIM2,TMPO,HIRA,LMF1" Drug 1385_UP Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ALCAM,ATP2B1,CFLAR,SLC24A2,PCYT1B,FEZ2,PPP6R2,DCAF8,ZNF337,INTS1,DPYSL2,EGR3,PLEKHO1,RASGRP2,VPS26C,EZH1,FHL1,SRCAP,PADI2,IPO5,MBD1,NF1,ODF2,ENPP2,PIK3CD,TRHDE,LRP12,MBOAT7,CNNM2,PTK2,ARID4A,SLC25A36,FBXW7,PAQR6,SFPQ,SGK1,RAB3GAP1,ARHGEF40,MAPKBP1,SPP1,ANKRD12,TBL1X,CBX5,CA14,MPPE1" Drug 1564_UP Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADD1,AGT,APAF1,RASL11B,ST3GAL5,KYAT1,CHRNB2,TMEM184B,NCOR1,CSF3R,SPATA2,DNM1,MED12,OLIG2,ENO2,IGSF6,VPS26C,ECSIT,FAM49B,PRRC2B,GPR12,CNTRL,DIDO1,ADAMTS13,KLF12,ITGAM,KCNN1,KHK,GIT1,TAGLN3,NPPA,MED1,SAFB,ITSN1,SLC1A7,SLC11A1,ZSWIM8,EPB41L3,MLC1,PDLIM2,ICAM5,TRPM2,SSBP2,SF1,LMAN2L" Drug 3538_DN Condelphine [7633-69-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AK2,BIN1,PPFIA3,ARRB1,CDK13,PDE8B,MARK4,SYNGR3,NMT2,SH2B1,CTH,ARHGEF4,RIMS3,DAPK3,DBN1,C2CD2L,TRAPPC9,DNM2,TOM1,EFNA3,ING4,EN2,LRRC23,ANKMY1,FER,HBS1L,ATXN2L,HNMT,MBD1,NPTX1,PCDH9,PRKAR1B,ATG16L1,RGS3,RGS10,GSTCD,WLS,SLC22A4,ZHX3,MAPK8IP3,PHLDB1,STX1A,TMOD1,VPS35L,MPPE1" Drug 4096_DN Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "RALGAPA1,TRMT9B,BIN1,CNTNAP1,AQP4,ATP1A3,SYNJ1,CACNA1A,LARGE1,FOXN3,PLEKHB1,DNAJB5,IQCK,AKAP5,ENTPD4,CREB5,ARHGEF10,PDE4DIP,EDRF1,KIAA0513,ST8SIA3,MRNIP,ZNF549,ETV1,FGFR1,SYT17,SEPT9,GLYR1,GRIK2,GRM1,LMO2,NUMA1,SERPINI1,RETREG1,PPP5C,PTPRN2,RPS20,PREX2,PPP4R3A,SLN,SCN3B,CHST8,ZMYND8,NPDC1,ZNF45" Drug 3989_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "MRTFA,CNTNAP1,APP,ALDH7A1,SYNJ2,KRIT1,RCBTB2,ARHGAP22,LHX2,AATK,PDE4DIP,TOX,RHOBTB1,PLPPR4,CHRDL1,IRAK4,MRNIP,STX2,FGF1,ANKFY1,DENND2A,C1QL1,KCNMB4,CNTRL,GRM8,ARHGAP19,INPP5B,MX1,PDE1C,STRN3,RC3H2,SYTL2,PTN,ENOX1,ZFP30,AMBRA1,FBXO11,CCDC88A,SS18,SYT1,TK2,ZNF711,NAV3,MPPE1,TIGD6" Drug 1674_DN Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP1B1,CAPRIN2,ASPH,NCOA1,ATM,BMP7,REPS2,CLCN3,COL4A5,DCAF8,TRAPPC9,DSCAM,TOM1,PHC2,VPS26C,SCML2,DPYSL4,ZNF44,ZNF276,HTATSF1,GSN,MAP4,MAPT,MSRA,MYO9A,SLC25A23,GON4L,PTK2,TMEM231,RAB3A,SCMH1,SLC20A2,PDZRN3,TROVE2,KANK1,FAM168A,EXOC7,FAM208A,PSD3,SSBP2,HIRA,MICAL1,ZNF45,PRDM2,NUP214" Drug 2521_DN Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG2,AMPD3,CDC42BPA,EP400,ZBTB10,STX16,SCAPER,C5,BAG4,FEZ1,CSNK1E,SIPA1L1,SLITRK5,PPP6R2,DTNA,ABI2,SORBS3,MTSS1L,ST3GAL6,FOXM1,SEPT9,POLL,LILRA2,CACFD1,LIG4,MAP4,GIT1,N6AMT1,ZNF862,ENPP2,PLCB2,RC3H2,MSANTD2,SGK1,RAB3GAP1,ARHGEF40,SLC12A2,SNCA,TROVE2,KAZN,CAMSAP2,PDLIM2,RBFOX2,PLPPR2,SH3GLB2" Drug 3043_DN Niacin [59-67-6]; Down 200; 32.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ARID1A,APBB2,ASPH,NRP2,MTMR2,VCAN,TM9SF4,KIAA0753,DNM2,ATN1,SIDT2,MRNIP,COQ7,PIPOX,CAMSAP1,OGA,GRM1,GRM8,GSN,MAP4,MEF2C,MGAT3,NOS1,PIK3CD,MAPK7,FAM120C,RAB3IL1,CEP97,KHDRBS2,MRAS,RASA3,FAM102A,SNCA,DOP1A,RAP1GAP2,ARHGEF9,PDLIM2,ADGRL3,DMXL2,TK2,TRPS1,FLRT2,ZNF225,NT5M,SSPN" Drug 4997_UP "Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "SYN3,SEMA6A,ASPH,SCAPER,BAIAP3,CA4,CANX,CLGN,HOMER3,CNTN1,NRG2,CREB5,TBC1D5,SPOCK2,SMG7,EDN1,HIPK3,VPS13B,DLC1,OGA,GLS,EML4,GRIK5,DHX35,ICA1,ITIH2,LIFR,NF1,NTRK2,PCDH9,PDE4A,PRKAR1B,PNMA8A,SBF1,SH3BP2,SLA,CCDC88A,KDM4B,RGL1,HIRA,UCHL1,EMSY,SEMA3B,SLC17A7,EPM2A" Drug 5387_DN Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "SEMA6A,CDC42BPA,FAM131A,PPFIA3,APP,PPP4R4,ADAM15,BTRC,CACNA1D,FEZ1,SIPA1L1,CNTNAP2,EDRF1,DBT,MFAP3L,ING4,MRNIP,HSD17B14,ACSL4,KAT8,SPACA9,HNMT,ITPKB,IPO5,KITLG,ADAM22,PLXNB1,STRN3,PRPH,PTHLH,RGS10,SH3BP2,ASAP3,ANKRD6,SLC1A7,ZHX3,LHPP,ST5,INKA2,PLCB1,ASTN2,TNS2,PCDHA6,AHCYL2,GDPD5" Drug 1492_DN Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG3,APP,CDK10,CDK13,BMP7,SYNJ2,SCARB1,REPS2,FOXN3,CNOT8,SLIT2,CRY2,GIT2,SLC12A6,FEM1B,FCF1,SUGP2,SORBS3,VPS26C,EZH1,ZNF589,FAM49B,PRELID3A,GPR153,COPS8,GNG4,HSF2,IL6ST,LIG4,CNOT4,PDE3B,MBOAT7,PPP2R2B,PPP3CC,PPP5C,RAB3IL1,GSTCD,FUZ,ZHX3,TROVE2,SS18,ARHGEF9,SYT1,TRPC1,MAP3K12" Drug 7411_DN Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ACLY,APC,CDK10,ATM,BMP7,CAMK2G,ARHGEF1,REPS2,ADGRG1,STOML1,IQCK,COL4A5,PDE4DIP,DAPK3,FBXL5,PARD6A,DTNA,SORBS3,TRMO,CINP,CGREF1,MALT1,GRB10,MAP4,PLXNB1,LRRC49,SAFB,ANKRD6,ZNF365,URGCP,PEX26,PPP4R3A,SLC15A2,RCOR3,LHPP,SS18,COBL,ANKRD28,TCF7L2,BEX4,METTL3,VAV1,NDRG4,SEMA3B,ST7" Drug 121_UP "estradiol, USP; Up 200; 0.01uM; MCF7; HG-U133A" Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ACTN1,BRAP,C1QTNF1,CDC42BPA,ASCL1,CFLAR,TBRG4,IQCK,ARNT2,DRP2,EFNB3,PLEKHA1,EPB41L2,DMTN,CEND1,TRMO,INPP5K,SCIN,KHK,MAP4,NFYA,ODF2,PMS2,LRRC49,TMEM104,TTC13,RALGDS,RGS3,RGS12,PAAF1,ABLIM3,SMARCC2,TMCC1,EMC1,ZBTB43,SRPK2,NXT2,CEP68,ANKRD28,EHBP1,WASHC4,CRTC1,RBFOX2,GDPD5,DPF3" Drug 4955_DN Carisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AMT,APP,CDK10,BTRC,KRIT1,ZFYVE9,CLU,FAM189A2,QKI,AKAP7,ARHGAP32,ARMCX2,HP1BP3,DTNA,CDKL3,EZH1,OLFM1,HTATSF1,CACFD1,HNMT,MAP4,ZNF862,NEK1,NPR2,NRGN,PIK3R1,PLCD1,STRN3,PRODH,PRPH,WDR25,PSMD13,PTHLH,ZCWPW1,TRAPPC13,SMTN,EMC1,SPTAN1,CEP68,PRRC2C,ARHGEF9,RPGRIP1L,KAT6B,REEP1,MPPE1" Drug 6231_DN Racecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABR,KIDINS220,CDC42BPA,NUMB,SYNJ2,MTMR2,SRSF11,NMT2,KIAA0586,DNAJC6,RCAN1,SEZ6L2,FEM1B,FGFR1,SEPT9,GART,GPR19,DIPK1A,MAP4,MITF,NCAM2,PLXNB1,TNPO2,CNNM2,TMEM231,GTDC1,RGS10,PAQR6,TRAPPC13,SH3BGR,ITSN1,RAB3GAP1,SCMH1,IFT122,WDTC1,TROVE2,FCHO1,EXOC7,TCF7,AHCYL2,TPD52,ZKSCAN5,VAV1,ZNF23,C12orf4" Drug 2909_DN Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG3,NDRG2,GRAMD1B,AP1B1,GAS7,MARK4,C5,ARHGEF1,SCARB1,PPP1R16B,LPAR6,ING4,EIF1,COQ7,ANKMY1,F8,SCML2,FGFR1,FLT1,USP19,KPNA5,MAP4,CCSER2,RETREG1,ZNF426,PTPA,PRKAB2,ZCWPW1,PLPPR3,SBF1,PPM1E,DZIP1,PEX26,MAPKBP1,STX1A,SYT11,TCF7,TCF7L2,PSD3,AP4E1,TNS1,PLPPR2,WNK1,URM1,NLRP3" Drug 6758_UP Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADD2,SLC4A4,N4BP2L1,CFAP410,MTMR7,CDC42,LARGE1,CHRNA4,NCOR2,CSF1,CTNND2,RIMS2,DCT,ABCC9,FGF1,FGFR1,DKK3,GABRA1,RUNDC3A,GNG4,GRM2,GRM8,ELOVL5,IGF1,IGFBP1,MBP,ADAM11,MMP16,NOVA2,NPPA,PALM,GPR85,RETREG1,TMEM231,KCNIP2,IL17RB,ZFP30,NTNG1,SNCA,IQSEC2,ATP10B,ADGRL3,TPM2,RUNDC3B,TRPC3" Drug 2854_DN Lovastatin [75330-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABHD6,BCL7A,BMP7,CAMK2G,SLC4A8,SDC3,TBC1D5,JAKMIP2,EDNRA,HSD17B14,F3,ACSL4,FGFR1,FHL1,FOXG1,DPYSL4,PDLIM5,CNTRL,INPP1,KCNF1,MATK,TM6SF1,GIT1,ADAM22,PC,POLG,ATG16L1,FAM184A,GTDC1,RGS10,ARHGEF10L,SCMH1,ZCCHC24,SPART,STX1A,FAM168A,VPS13A,ARC,ATP11A,CDK20,UBTF,VAV2,MICAL1,ZNF45,SMIM8" Drug 1181_DN 2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "GRAMD1B,OSBPL1A,MRTFA,KCNAB2,CAMK2G,CD38,FADS2,HOMER3,C2CD2,CREM,CSF1R,RUBCN,NR1D2,DPH1,EIF4G1,COQ7,RASGRP2,PTK2B,POLR1B,TMEM164,FGR,SEMA4D,GRB10,DIDO1,BTN2A1,LSS,MBD1,PPP3CC,PRKCZ,GTDC1,EXD2,CASC3,PEX26,ARFGAP1,TEX2,CLASP2,GSE1,KCTD2,KAT6B,UBTF,VAV1,NSD2,XRCC4,WIPF2,EPM2A" Drug 3300_DN Pilocarpine nitrate [148-72-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADORA2A,AP2A2,AK2,CDK13,ALDH4A1,ATM,KIF1A,CFLAR,SYNJ2,CACNA2D2,SOCS6,CLCN3,FAM189A2,SH2B1,EDRF1,DAPK3,MFAP3L,FGFR1,FHL1,C1orf61,FAM49B,ERAP1,DISC1,RUNDC3A,TXNL4A,CACFD1,DHX35,ICA1,NRGN,PLEC,PPP5C,RAB3A,RGS12,SH3BP2,SLC20A2,LIMCH1,UNC5B,SPTAN1,EXOC7,KIAA0930,TK2,XRCC4,ZBTB14,GDPD5,ST7" Drug 3635_DN Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "GAS7,SEMA4G,ALDH7A1,CADM3,GYG2,BAIAP3,CDO1,ASIC3,DNAJB5,AKAP6,WHRN,AKAP5,RASSF2,MFAP3L,EFNB3,CEND1,FOXG1,GNG3,GSN,KCNN2,MOBP,PCDH9,CDK18,PLCD1,PPP5C,PRKAR1B,PTHLH,KCTD17,ZFHX4,SUPT20H,BCAN,SLC2A5,SLN,CXXC4,WDTC1,ARHGAP26,SPTB,CRTC1,TGFBR3,TNS1,TRPM2,FLRT2,PLPPR2,VIPR2,SYNC" Drug 4992_UP Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "MRTFA,BIN1,CDC14B,SYNJ2,BAIAP3,NEURL1,CDH10,CRLF1,FOXN3,CHN2,CHRNA4,TAOK2,ABI3BP,NOS1AP,DLC1,CAMSAP1,FYB1,GABRG2,SRCAP,GFER,CACFD1,SYNPO,KCNN1,ADAM22,NOVA2,PDGFRA,PENK,PILRA,POU3F2,ATG16L1,MYH14,SH3GL3,CNKSR2,MAPKBP1,WDTC1,PEG10,ZC3H13,NPAS3,MAPK8IP3,WSCD1,SEZ6L,TRPM2,RPRM,NT5M,PLSCR4" Drug 326_DN rapamycin; Down 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "CASK,PDE8B,CLCN4,PICK1,IFFO1,CP,CNTNAP2,KLHL3,DNAH9,EIF5,EPB41L2,LRRC23,STX2,CORO2B,FGFR1,TBR1,SRCAP,HTATSF1,GNAO1,MAN1B1,KCNJ5,KHK,FXYD6,PTPRN,ZC3H14,FOXRED2,SH3BP2,FNDC3A,ABLIM3,PKNOX2,SLC11A1,CDK5RAP2,PALLD,EMC1,SPTB,NXT2,SEPT8,ATP11A,TRIM2,SLC35G2,TF,TMPRSS5,SLC13A3,UPF3A,PHTF2" Drug 7227_DN Nadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ASPHD1,MTUS1,EPB41L5,PPFIA3,CFLAR,SCARB1,QKI,HOMER3,CREM,ABCG1,LRIG1,FAM169A,PPP6R2,DBT,FBXL5,PARD6A,RABGAP1L,TOM1,SUGP2,RGS17,CDKL3,F3,EFEMP1,FOXG1,DPYSL4,DISC1,GRB10,AGBL5,KCNJ3,NCAM2,LRP12,MBOAT7,FSD1,PRKAB2,GON4L,SEC61A2,ROBO1,RPS6KA2,SBF1,PPP4R3A,ITPRID2,MAPK8IP3,CEP68,KAZN,TCF7L2" Drug 313_UP NU1025; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "BIN1,KCNAB2,GAS7,APP,ARRB1,ARRB2,ATP6V0A1,MTMR2,CFAP410,CAST,CD38,CHRM4,CHRNB2,CSF1,FRMPD4,ING4,TNK2,ERCC2,TRMO,CYP46A1,MALT1,RUNDC3A,TXNL4A,GRM2,NXPH3,KIF2A,ADAM22,MYO7A,ODF2,FXYD1,EPN1,WDR25,PAQR6,FOXRED2,ATXN2,ABLIM3,KDM4B,ZCCHC24,NMNAT2,UNC5B,SPTB,UGT8,LMF1,ZNF23,GJC2" Drug 4024_DN Chlorogenic acid [327-97-9]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,ATP2B3,ALDH7A1,CACNA1I,CAMK2B,CHI3L2,ARHGAP22,NRXN3,ABCG2,DNAJB5,WHRN,SH2B1,MICAL2,BRINP1,SPOCK3,SIDT2,FGF1,AFF2,C1QL1,POLL,GUCY1A2,GIT1,NF1,PBX1,FSD1,ZSCAN32,RALGDS,KCTD17,FRMPD1,ASAP3,FNDC3A,SLC1A7,FAM214B,SLC6A9,SLC20A2,SLN,SPTAN1,DNAH7,THRA,WIPF1,XRCC4,NDRG4,SLC17A7,KCNAB1,MPPE1" Drug 2519_DN Avermectin B1 [71751-41-2]; Down 200; 4.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP2A2,CDK13,DNAH17,N4BP2L1,KIF1A,LDLRAD4,TAOK2,ZFYVE9,CDON,DTNA,TSPAN5,EFNA3,LRRC23,F5,KAT8,ZNF589,PDLIM5,CAMKK2,GABRA2,SEPT9,GLYR1,GRM8,PADI2,MAP4,MID1,CNOT4,OLR1,OXTR,ENPP2,PENK,PIK3R1,SLC25A23,ITSN1,FAM102A,SLC15A2,SLC20A2,STX1A,JMJD6,IQCE,TNS2,THRA,RBFOX2,TPM3,FLRT2,XRCC4" Drug 7208_DN Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ASPHD1,MADD,EIF4G3,QKI,SIPA1L1,PDE4DIP,PPP6R2,KIAA0753,SMG7,DMPK,EPB41L2,SEMA4D,ZNF276,KCNMB4,GRB10,DHX35,INPP5B,KCNK1,MAP4,NUMA1,SETD4,SLC25A23,RIPOR1,RXRA,EPN2,SLC15A2,ERC1,ZBTB43,POGZ,ELOVL4,CEP68,EXOC7,TCF7L2,ARHGEF12,AHCYL2,CABIN1,SSBP2,RPRM,UBTF,LMF1,XRCC4,SF1,ZNF189,NUP214,ACTR3B" Drug 7130_DN Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AK2,APC,SLC4A4,B4GALT6,FADS2,NIPBL,CHD1L,ARHGAP32,SPATA2,RABGAP1L,DLG3,TNK2,HSD17B14,ERBB2,SCML2,TACC2,POMT1,DENND2A,ZMYND11,DISC1,COPS8,PRRC2B,HNMT,IL6R,MAN2A2,NFYA,CNOT4,RGS4,KIRREL1,SBF1,ATXN7,RAP1GAP2,PBLD,NCDN,DIP2A,STX1A,ARHGEF9,NSD1,AHCYL2,FAM155A,UBE3A,BCL2L13,LMF1,MAP3K12,ACTR3B" Drug 3582_DN Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AP2A2,MRTFA,CDC14B,PRX,ARRB2,MARK4,ATM,CFLAR,SCAPER,BTRC,CACNB2,LHX2,SH2B1,PDE4DIP,GREB1,NOS1AP,ARMCX2,MFAP3L,RUSC2,C2CD2L,SIDT2,EIF4G2,SORBS3,EXTL2,CAMSAP1,SEMA4D,OGA,RUNDC3A,KCNH2,KPNA5,PACSIN1,MAPK7,RGS10,NLGN1,RBM34,SMG6,ZEB1,CRTC1,TMEM121,HEY2,FAM155A,PLPPR2,KCNK12,ZBTB14,SCG2" Drug 4717_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "AK2,LTBP4,MADD,MARK4,ATM,CFLAR,BTRC,CA4,WHRN,SLC4A7,NECTIN3,ENTPD4,CRY2,MICAL2,ARHGEF4,NOS1AP,CTIF,MFAP3L,RABGAP1L,DNM2,DSCAM,RCAN1,EDNRA,OPTN,AASS,MRNIP,ZNF589,FHL1,GFER,ITPKB,KIF5C,KPNA5,MPP2,LRP12,PPARA,RAB3IL1,FAM184A,ZNF821,KIF13A,EXOC7,SMG6,TCF7L2,TRIM2,ZMYND8,VIPR2" Drug 5514_DN Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "SLC12A5,SRPX,CASK,NCOA1,SLC4A4,CFLAR,SPAG9,IQCK,NECTIN3,SOCS5,DOCK4,DCAF8,KIAA0513,DBT,KIAA0753,SMG7,DLG3,FHL1,MALT1,NR3C1,VWA5A,MIA2,GIT1,NF1,NRGN,FA2H,FSD1,RGS3,TRAPPC13,PREX2,FAM214B,CDK5RAP2,TSPYL2,ELOVL4,NSFL1C,POPDC3,TACC1,TRIM2,PARD3,ZNF384,METTL3,HIRA,TFIP11,MPPE1,RNF170" Drug 5227_DN thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ALAD,PPFIA3,CDK10,CFLAR,NFS1,B4GALT6,LHX2,NMT2,ENTPD4,FAM169A,HDAC4,RIMS3,EXOG,RBM12,EPB41L1,KAT8,SRCAP,MALT1,ARHGAP19,DHX35,KCNJ3,MAPT,MPP2,OGDH,PDE4A,PLEC,RIPOR1,NKAIN1,RAD51D,SUSD4,GTDC1,MAPK12,SLC1A7,SMTN,PDZRN3,KANK1,ASTN2,PSD3,PCDHA6,AP4E1,ZNF34,TMOD1,ZKSCAN5,MVB12B,SMIM8" Drug 5044_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "MTUS1,LGR5,ARRB2,STX16,CFLAR,MAP7,KYAT1,CDC42,VCAN,SLITRK5,GIT2,KIAA0753,EXOG,DPH1,OPTN,EFNA3,EGFR,ING4,PLEKHO1,FER,GLRB,GNAS,SHISAL1,IL6ST,INPP5B,MPP2,NDP,PIK3R1,PLCD1,STRN3,POLG,SAMD9,PTPN13,SEC61A2,DHX30,SPTAN1,CLASP2,THSD1,SS18,TK2,SSBP2,ZKSCAN5,LMF1,ZBTB14,ZNF711" Drug 7512_DN CP-863187 [668981-07-5]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ABHD6,PPFIA1,ARNTL,ASPH,ZBTB10,ADAM15,CFLAR,SYNJ1,CHN1,QKI,CNN3,ARHGAP32,G3BP2,E2F5,SEC24B,STAU2,TRAF3IP2,ATXN2L,KIF2A,IPO5,MBNL1,NCF2,NF1,OCRL,LRP12,RDX,TMEM156,HSPA4L,SH3GL3,FNDC3A,TTC17,LIMCH1,PDZD2,PEG10,FBXW11,TCF7L2,WASHC4,FRYL,RBFOX2,TPD52,TRIO,TRPS1,NSD2,CLDND1,WNK1" Drug 2958_DN Etomidate [33125-97-2]; Down 200; 16.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADORA2A,PDXK,CASK,MARK4,NUMB,SLC4A4,ATP2B1,BCL2L2,SCAPER,CD86,CLGN,RAB28,SH2B1,VCAN,CX3CR1,SGSM2,ABI2,EGR3,COQ7,F3,SCML2,KIAA1109,PDLIM5,SRCAP,ADAM28,LILRA2,STON1,ZNF862,SETD4,PTPA,PPP3CC,CEP97,FAM184A,SLC2A5,BTBD3,SIRT2,ZNF667,WDTC1,NSD1,TPM1,SSBP2,UBE3A,EMSY,PRDM2,MARCH8" Drug 7197_DN Isoniazid [54-85-3]; Down 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ASPHD1,RBM10,ARID1A,AP2A2,BIN1,APBA2,BCAS1,PPFIA3,MARCH3,KIF1A,NFS1,ARHGEF1,PICK1,SH2B1,ABCG1,SOCS5,SDC3,DLG3,DNM1,MED12,LRRC23,ZNF589,FHL1,GABRA2,MSL3,DHX35,IL6R,KCNF1,MBD1,MID1,MITF,SMIM7,MBOAT7,PPP3CC,PRKAR1B,RIPOR1,PAQR6,ASAP3,SIRT2,ARHGEF9,MTCL1,VGF,HPS4,NUP214,RNF170" Drug 7335_DN Ethamsylate [2624-44-4]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG3,APP,CDC14B,RIPK1,MPDZ,BCL7A,BAG4,CREM,FEZ1,CTH,PARD6A,SGSM2,EPB41L1,DMTN,F3,BAIAP2,SRCAP,AHDC1,GLYR1,MUM1,ARHGAP19,MATK,KITLG,ZNF862,NUMA1,RETREG1,PLEC,STRN3,PPP5C,MAPK8,CEP97,ZCWPW1,TCP11L1,ITSN1,WDTC1,EMC1,TCF7L2,SZT2,TMEM121,PARD3,KAT6B,CABIN1,LMF1,UBE3B,SMIM8" Drug 4079_DN Sotalol hydrochloride [959-24-0]; Down 200; 13uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "APBB2,MARK4,SLC4A4,ADAM23,MPDZ,SYNJ1,CACNA1I,CFAP410,CACNA1A,AKAP7,ARHGEF10,PPP6R2,EDRF1,DNM2,DLC1,FGF1,SCARA3,SYT17,TDRKH,LPAR4,ACOT7,LMO2,MDFI,MIA2,TAGLN3,OPCML,P2RY1,SYTL2,GON4L,WDR25,ZSCAN2,ASAP3,LHPP,THSD1,MAPK8IP3,FAM168A,SYT11,PCDHA5,TNS1,TRIO,OSBP2,WIPF1,LAT2,NPDC1,NT5M" Drug 2301_UP Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ACTN2,ADORA2A,C1QTNF1,MRTFA,ASTN1,ALDH4A1,FGF17,GYG2,CACNA1I,NEURL1,CLGN,CHN2,ATRNL1,HIPK3,ING4,KCNMB2,ERCC2,ZNF589,AGAP2,RND1,GLS,MSL3,GRM7,NXPH3,ICA1,KCNMA1,MGAT3,KITLG,CD200,NTRK3,PENK,PLTP,PACSIN1,CCDC40,RAD52,KLHDC8A,SH3BP2,BCAN,MYH15,IZUMO4,TROVE2,SMG6,PCDHGA10,TNS1,WIPF1" Drug 7060_DN SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NME5,PPFIA3,ARHGAP5,CDK13,MARK4,ASPH,CFLAR,SLC25A14,CBFA2T2,NIPBL,SLC4A7,DCAF4,ZFYVE16,GIT2,DNAJC6,LYPD1,EFNB3,SEC24B,DPYSL4,CGREF1,POLL,PRRC2B,GRB10,NR3C1,INPP5B,PCDH9,PPARA,MINDY2,PPM1B,PPP5C,WDR25,BSDC1,WLS,SBF1,SEC14L1,SH3BP2,KIF13A,ELOVL4,KAZN,SEMA4A,DMXL2,RPGRIP1L,TRIO,MPPE1,UBE3B" Drug 2306_DN Salbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "C1QTNF3,APBB2,APOC1,ARRB2,MARK4,SCAPER,HIP1R,B4GALT6,NMT2,CRY2,FAM169A,PPP6R2,DCAF8,TBC1D5,DAPK3,PHF20L1,SORBS3,COQ7,ANKMY1,KIAA1109,FHL1,POLL,GRM1,GRM7,HNMT,INPP5B,KIF5C,MAP4,PALM,RETREG1,NLE1,PRPH,FAM184A,TRIM68,FBXW7,FNDC3A,SMARCA4,SMARCD3,MAPKBP1,WDTC1,CDK19,DOCK9,CHST8,KLC2,GDPD5" Drug 4585_UP Captopril [62571-86-2]; Up 200; 17.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADCY2,PLA2G6,ADGRF5,LTBP4,AMPH,GAS7,PPP4R4,DNAH17,SYNJ1,CACNA1I,CACNA1G,LDLRAD4,CD86,ARHGEF2,CHGA,ASIC3,ABCG2,NCOR2,RIMS2,SGK2,EPHB1,REEP2,AGAP2,B3GAT1,DKK3,SIGLEC8,GRM1,GUCY1A2,VWA5A,MATN3,NNAT,PRKAR1B,MYH14,KLHDC8A,CCDC102B,ZNF821,SPTB,PHLDB1,RIMBP2,TNS1,TPM2,TRO,TRPC1,NUP214,GAN" Drug 609_UP 5666823; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG2,BRAP,ADORA1,APOC1,PPFIA3,RGS11,RAB29,CHN1,NIPBL,DLG3,SGK2,SIDT2,EFNB3,EXTL2,TBC1D16,AFF2,STAU2,B4GALNT1,NCKAP1,RNFT2,SLC2A6,KIF5A,MAP4,MAPT,NELL2,SETD4,PFKFB2,PLCD1,PPP5C,QDPR,ARID4A,GSTCD,PCMTD2,TCP11L1,GALNT10,SNAP25,WDTC1,HECW1,TROVE2,TBL1X,DMXL2,OBSL1,TNS2,GDPD5,DPF3" Drug 7061_UP SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "NDRG2,KCNAB2,CA4,FOXN3,LHX2,QKI,HOMER3,SLC4A7,CRY2,ABCG1,LRIG1,CYBB,DTNA,STX2,BAIAP2,FHL1,ERAP1,AHDC1,GLS,CACFD1,LMO2,MGAT3,NPR2,SLC11A2,PLCD1,POLG,RIPOR1,RAB3A,RGS12,RNASEL,GSTCD,ZNF821,WDTC1,TROVE2,POGZ,ST5,PHLDB1,SEMA4A,EXOC7,KIAA0930,TCF7,CHST8,REEP1,UPF3A,SSPN" Drug 2463_UP "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "ADCY6,ADD2,CNTNAP1,SYNJ2,CACNA1G,HIP1R,MAP7,CDO1,CBARP,RAB26,CREM,CRMP1,DCAF4,DAPK1,KLHL3,DLG3,EEF1A2,RASGRP2,CD320,FGFR1,FOXG1,TMEM8B,ATP8A2,KIF3A,ITGAM,KHK,ADAM22,NAP1L2,NOVA2,OPRL1,PURG,PPARA,PTPN13,PTPRD,PID1,SYNDIG1,SNCA,TNIK,SLC19A3,GPR161,TMOD1,CDK20,AMACR,VSNL1,SH3GLB2" Drug 1713_DN Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; HL60; HG-U133A Broad Institute CMAP Down 5.41E-03 1.00E+00 2.84E-02 3.23E-01 45 197 "C1QTNF1,STX16,SPAG9,FOXN3,MAP4K4,RAB26,ARHGEF10,SPOCK2,SGSM2,IGSF6,FGFR1,BAIAP2,C1orf61,NEU3,PCSK1N,PRRC2B,DIDO1,SPACA9,IDH3A,MAP4,MBD1,MEF2C,SCAMP5,AFF1,NTRK3,ZNF426,PPP2R2B,RAD51D,RFX5,MYH14,EXD2,AMBRA1,SLN,SNAP25,ZSWIM8,EMC1,THSD1,TAC3,MCF2L,KCTD2,CABIN1,VGF,EPM2A,ST7,AAAS" Drug CID000001054 pyridoxine Stitch 5.44E-03 1.00E+00 2.85E-02 3.24E-01 25 95 "ABAT,ALAD,BBOX1,PDXK,ALDH7A1,MTMR2,CBS,CHRNA4,FADS2,CTH,VPS13B,GAD1,GAD2,GLS,GPT2,NR3C1,KCNQ2,MTR,OGDH,PSAT1,PYGM,RPE,KDM3A,ETNPPL,NETO1" Drug CID000003350 H045 Stitch 5.44E-03 1.00E+00 2.85E-02 3.24E-01 20 71 "KCNH8,DYNLL1,ATP6V0A1,CACNA1E,NGB,CLU,DBI,STX2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HBA1,IGF1,NELL2,POU6F1,PDZD2,PMEPA1" Drug CID000071249 diprafenone Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "ASIC1,ASIC3,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug CID000126806 CASs Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "AMH,LDHD,EXOG,SLC29A4,FDFT1,GLS,DICER1,TST" Drug ctd:D000526 Alprenolol CTD 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "ADRB2,ARRB1,ARRB2,EGFR,GNAS,HTR2A,NPPA,MAPK3" Drug CID000123788 Super-Bond Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "ABR,KDM5D,CNOT8,ARHGAP32,F8,L1CAM,RAD51D,SALL1" Drug CID000002227 arcaine Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "CARS,DTNB,B3GAT1,GRIK1,GRIN2C,GRIN2D,PDYN,TACR1" Drug CID000010315 butyrophenone Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "CRYM,DRD1,RASL12,HTR2A,KCNH2,POU6F1,PTPRD,RASGRF1" Drug CID000590836 k143 Stitch 5.47E-03 1.00E+00 2.87E-02 3.26E-01 8 19 "APC,NCOA1,CALB1,DMPK,POLK,INPP5K,PPARA,TP53BP2" Drug ctd:D000452 Aldrin CTD 5.49E-03 1.00E+00 2.87E-02 3.27E-01 48 213 "ACLY,ALK,GPAM,ALS2,ADGRB2,MPDZ,ST3GAL5,USP2,CHRNA4,ACBD5,PLCH2,AIF1L,ATL1,MBNL2,SORBS3,PIPOX,TACC2,DKK3,SEPT9,GFRA1,GPR12,LPAR4,SCIN,KCND2,KIT,LMO1,LSS,MAP4,MEIS2,CD200,NTRK2,PDGFRA,PFKP,CDK14,RETREG1,PSAT1,LRRC49,VEPH1,RET,RXRG,LIMCH1,ZHX3,VAMP1,SYT5,MTCL1,TOM1L2,VANGL2,NHSL1" Drug CID000445141 AC1L9HHR Stitch 5.50E-03 1.00E+00 2.88E-02 3.27E-01 74 354 "ACLY,ACTN1,ADCY2,ADCY5,ADCY6,ADCY8,SYT13,ANK1,ANXA7,APLP1,DGKZ,GPAM,DGKD,SPTBN4,CALB1,CALM1,AIFM1,SCARB1,DGKI,LRBA,CHN1,CLTC,BOC,DGKB,DGKG,DNM1,RBM12,EPB41,F3,F5,F8,TUBB4A,FOXG1,PSD2,GALC,GAP43,ATP8A2,GSN,MYLK2,SCIN,KLHL23,SYTL4,MBP,NRGN,OLR1,P2RX7,PIK3C2A,PIK3CD,PKM,PLCD1,PLP1,PLTP,PMP2,EXOSC10,POLR2F,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,MAPK8,SYTL2,GSTCD,SCP2,SMPD3,RPH3A,SPTAN1,STAU1,JMJD6,PLCB1,SYN1,SYT1,ATP11A,TPD52L2" Drug 2429_DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.50E-03 1.00E+00 2.88E-02 3.28E-01 40 171 "CDC42BPA,EP400,APP,ATP2A2,SCAPER,CLGN,RAB33A,QKI,C2CD2,ARHGEF10,CSNK1E,VCAN,SACS,KBTBD11,RBM12,RACK1,CAMSAP1,GRB10,HMGCR,LSS,NUMA1,OPA1,ZNF493,ZDHHC14,RPS6KA2,SH3BP2,SLC6A8,SPP1,CDK19,ZC4H2,VAMP1,VPS13A,DICER1,SLC44A1,CBX5,RBFOX2,VLDLR,NSD2,LRP8,NETO2" Drug 5208_UP retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.50E-03 1.00E+00 2.88E-02 3.28E-01 40 171 "ADORA1,C1QTNF1,ARRB1,ATP6V0A1,CFAP410,CA12,CDC42,CRY2,CSF1,MICAL2,PDE4DIP,DRD1,MBNL2,EPB41L1,SH3YL1,RAB30,KCNJ5,LMO2,ZNF862,PFKFB3,MAPK8,KLK6,SAMD9,RAD52,RAP1GAP,FBXW7,SELL,SLC22A4,LIMCH1,TSNAXIP1,KAZN,TRIM2,DOCK9,TGFBR3,R3HDM1,KAT6B,NPL,GDPD5,SEMA3B,SSPN" Drug CID005459389 DB04780 Stitch 5.50E-03 1.00E+00 2.88E-02 3.28E-01 40 171 "ARSE,ASPA,CLTB,QKI,GAL3ST1,VCAN,ARHGEF4,ERCC2,F3,B3GAT1,GALC,NEU3,GFAP,ADAMTS8,HMGB1,MAG,MBP,MOBP,MOG,RSPO2,NACA,OMG,PLP1,PMP2,FA2H,PRKCB,PRKCG,PKN2,PRKCZ,KLK6,SELL,BCAN,ST8SIA1,IFT122,THSD1,THBS4,TNR,UGT8,SPHK2,SENP7" Drug 6713_DN Monobenzone [103-16-2]; Down 200; 20uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "APP,CDK13,ASPH,STX16,ATP2A2,CHM,RAB28,PLAA,HOMER3,TBC1D5,HP1BP3,FCF1,MBNL2,ETV1,RRAGB,ZNF589,KIAA1109,ANKFY1,TRMO,PDLIM5,ZMYND11,PSRC1,CNTRL,IL6ST,INPP5B,MITF,PAK3,RC3H2,POLR2F,MAPK3,SAFB,SCN8A,LIMS2,SPTAN1,SS18,NXT2,ARHGEF9,ZEB1,RBFOX2,TSN,NSD2,NDRG4,EPM2A,AAAS" Drug 4496_DN Pindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "ALAD,APBB1,APC,ADAM15,ADGRB2,CDK5R1,SYNJ1,CCNT1,ARHGEF2,CLCN4,LY86,CREM,DAPK3,EDNRA,EGFR,ZNF589,BAIAP2,FHL1,GCNT2,GUCY1B1,IL6ST,INPP5B,KIF5C,MAPT,NFYA,NUMA1,ODF2,PLXNB1,FSD1,WDR25,FAM120C,RPS6KA2,FNDC3A,ZNF667,CDK5RAP2,COLGALT2,NXT2,SYT1,ATP11A,SYNE1,TK2,ZNF45,SEMA3B,EPM2A" Drug 4268_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "SPARCL1,ASCL1,CCDC181,ATP2B2,N4BP2L1,CACNA1D,CACNG1,CAMK2B,CCKBR,CSF1,RGS6,PLCH2,EDRF1,ATN1,FRY,EPHB1,REEP2,FAM198B,MYOZ2,GFRA1,GPM6A,GPR17,GRK4,TPPP,ADAMTS8,GRM8,KCNF1,MSR1,MYCN,NF1,PBX1,PDE4A,RETREG1,EPN1,SELL,DZIP1,SLC11A1,KIF21B,MCF2L,SLC19A3,TLR4,OSBP2,MVB12B,JPH3" Drug 4356_UP Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "NDRG2,FZD9,APAF1,GAS7,ALDH7A1,CDK5R2,RUNX1T1,JAM2,SULT4A1,CRMP1,FAM169A,SEC14L5,EDNRA,EFNB3,BAIAP2,GATM,GFAP,GNAO1,GRM7,GUCY1A2,HLF,NPY,NOVA2,PALM,PLCD1,PLTP,PACSIN1,FAT4,RPS6KA2,SLC2A5,CCDC88A,SLC11A1,SORCS3,ZNF415,ZCCHC24,KIF21B,SPTB,ATP10B,EXOC7,ADGRL3,THRA,UGT8,LAT2,SLC30A3" Drug 4449_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "AMPD3,BIN1,CDC42BPA,APAF1,APBB2,APOC1,SEMA4G,ATP6V0A1,ADGRB2,ADGRG1,LHX2,COL9A3,NRG2,MICAL2,HIPK3,SIDT2,CELSR3,NCALD,CGREF1,GBX2,SHISAL1,KCNJ5,MN1,ZNF862,OPRL1,PFKFB4,PLCB2,WDR25,RAB3A,BEND5,TMEM206,SAFB,ATXN7,MRAS,PPP4R3A,ARHGEF40,SLC9A5,SMG6,CHST8,VAV2,VIPR2,TRIM9,TFIP11,PHTF2" Drug 7526_UP 15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "PPFIA1,SEMA4G,CDK5R1,C5,MAP7,CNOT8,CREB5,AKAP12,NCOR2,CTH,CNNM1,FRY,EGFR,DCTN2,GART,GCNT2,GPR19,CACFD1,DHX35,LSS,MIA2,MKLN1,NFYA,ZNF426,SYTL2,PTPRH,PTPRN2,PID1,ZDHHC14,RGS4,PPP4R3A,FAM214B,BTBD7,SS18,MAPK8IP3,CEP68,VPS13A,AHCYL2,UGT8,OSBP2,ZBTB14,ZNF225,EVI5,SMIM8" Drug 6714_DN Hesperidin [520-26-3]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "ACLY,KIDINS220,PKP4,APP,CDK13,ASPH,ADAM15,CFLAR,SYNJ2,MTMR2,CANX,MAP7,KRIT1,CHM,CNOT8,QKI,OSBPL3,TBC1D5,EIF5,PLEKHO1,ETV1,FCGRT,PDLIM5,ZMYND11,ERAP1,INPP5K,GCNT2,MSL3,HNMT,JAK2,SCAMP5,MITF,NEK1,PFKFB2,RIPOR1,TAB2,BEX4,TSN,UBTF,NSD2,XRCC4,ZNF711,NDRG4,UBE3B" Drug 5607_UP Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "DPF1,NDRG2,ADD2,C1QTNF3,SEMA6A,PLA2G4C,MARK4,DDX3Y,KSR1,NEURL1,CLCN4,CTIF,RUSC2,DMPK,EDNRA,ING4,FGF1,FGF13,GFER,RND1,STON1,SPACA9,AFDN,MYH7,NOVA2,NUMA1,PLCD1,PURG,C1orf54,GAL3ST4,RGS12,TTLL7,KANSL3,KIF13A,SOX2,PEG10,PHLDB1,POPDC3,SEMA4A,WSCD1,HEY1,UCHL1,ITM2C,AP3B2" Drug 1589_UP Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "CNTNAP1,EIF4G3,CFLAR,BMP7,SYNJ2,CA12,CD86,CD38,TAOK2,RAB28,ZFYVE9,LETMD1,CRMP1,MICAL2,PPP1R16B,DMTF1,SIDT2,MBNL2,ABI2,EGR3,RASGRP2,IGSF6,VPS26C,CACFD1,PADI2,TJAP1,ITGAV,NELL2,NTRK2,NTRK3,SMOX,PTX3,RNASE1,FAM102A,AMBRA1,ARHGEF40,CCDC88A,SLC11A1,KDM4B,EPB41L3,STXBP1,GORASP1,FLRT2,SLC17A7" Drug 4152_DN Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "NDRG2,AMPD3,APLP1,CACNA1A,CACNA1D,CAMK2B,FOXN3,SLIT2,FADS2,CRY2,SNCAIP,DBN1,EDNRB,MBNL2,MRNIP,NEU3,ALDH1L1,GLYR1,GSN,ATXN2L,MYT1,NF1,CDK18,PDE3B,PLCD1,FSD1,NKAIN1,TCP11L1,ZNF821,FNDC3A,ABLIM3,LIMS2,SLC9A5,COA1,SNCA,KIF13A,PHLDB1,SYT5,TBCEL,TMEM121,HEY2,TRPM2,SPHK2,MPPE1" Drug 3753_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "ADD2,ALK,CDK10,SPAG9,AP4M1,CHM,PICK1,CRMP1,EDRF1,DAPK3,SMG7,EDN1,SORBS3,ETV1,DCTN2,CINP,ARFIP1,GLYR1,IL11RA,JAK2,MX1,MYO6,NEK1,NF1,NFYA,NPR2,LRP12,PRPH,FAM120C,RAD52,RGS4,FNDC3A,ELMO2,SMARCA4,PEG10,ATP10B,EXOC7,SMG6,SYNE1,CHST8,GPR161,TMPO,UGT8,WNK1" Drug 7092_DN GSK-3beta Inhibitor VIII; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "ADD1,MRTFA,PPFIA3,CDK13,RIPK1,BACH1,SYNJ2,CAMK2G,FAM189A2,HOMER3,WHRN,CREM,HINFP,FEZ1,NR1D2,RCAN1,DTNA,EIF5,FGFR1,GHR,ZNF276,TXNL4A,GPER1,ICA1,INPP5B,MBD1,NEK1,NFYA,NUCB1,PC,CEP97,BSDC1,CLIP1,SFPQ,EPN2,KDM4B,SOX3,CEP68,ASTN2,ANKRD12,TBL1X,BCL2L13,FZD3,MARCH8" Drug 4462_DN "ICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "CNTNAP1,APC,CDK10,MARK4,ADGRB2,MTMR3,CLCN4,CNTN1,COL9A3,TCEAL2,CREM,ARMCX2,DNM1,PLEKHO1,FGF1,GNAS,ATXN2L,LSS,KITLG,MX1,NF1,PBX1,PFKFB4,PLCB2,PLEC,RGS7,SUGCT,MYH14,ASAP3,SIRT2,IQSEC2,DDN,LHPP,SAMSN1,MAPK8IP3,EXOC7,SMG6,GPR161,TIAM1,PLPPR2,ZNF711,ZNF74,SH3GLB2,EPM2A" Drug 2450_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 5.55E-03 1.00E+00 2.90E-02 3.30E-01 44 192 "ARID1A,KIDINS220,ALAD,MRTFA,BCL7A,NFS1,HOMER3,CREM,SPATA2,ZNF804A,SGSM2,DNM2,EFNB3,CELSR3,EIF4G1,CDKL3,FGR,AGAP2,GABRA2,ALDH1L1,LSS,MYO7A,NINJ2,NPR2,NUMA1,PPP5C,RGS10,TMEM206,EMID1,MRAS,SH3BP2,SPTAN1,STX1A,ADGRL3,TCF7L2,CABIN1,TRPM2,VIPR2,BEST1,LMF1,ZNF142,PRDM2,TIGD6,AAAS" Drug CID000005300 NSC236997 Stitch 5.56E-03 1.00E+00 2.91E-02 3.31E-01 107 539 "ABR,ADCY2,ADCY5,ADCY6,ADCY8,ADRB2,AGT,ALAD,ZNF687,OGT,GPAM,APOC1,APOC2,AQP6,SLC2A11,ALDH7A1,BBS2,CALM1,CAPN3,CBS,CCK,RGN,AIFM1,CD86,COL4A5,CP,CS,VCAN,ZEB2,MYEF2,LYPD1,EBF1,EDN1,EDN3,EDNRA,EDNRB,EGFR,CD320,KAT8,FOXO3,OGA,GAA,GAD1,GAD2,GATM,GCK,MSTN,GFAP,USP19,GHR,PPARGC1A,GLS,GPD1,GPD2,NR3C1,CIT,HBA1,HMGB1,HMX1,CPT1C,AGFG1,IRF8,MYLK2,IGF1,IGFBP1,SFXN5,MBP,MITF,MMP16,MMP17,NEUROD1,NOS1,NPY,NPPA,P2RX7,PAH,GPR85,PFKFB2,PFKFB3,PFKFB4,PFKP,PKM,PPARA,PRKCB,PRKCZ,MAPK9,PTPRN,PTPRO,PYGM,RIT2,GSTCD,S100B,FNDC3A,SLC14A1,SPP1,PEG10,PBLD,SST,APOM,TAC1,TAC3,ZEB1,SIRT1,THRA,TRH,XRCC4,NETO1" Drug CID000123166 vinyl Stitch 5.61E-03 1.00E+00 2.93E-02 3.34E-01 29 115 "ABAT,ABHD6,PDXK,NGB,CBS,CHN2,NCOR2,BOC,PLEKHM1,HEPH,CHRDL1,RCAN2,F8,TUBB4A,ST6GALNAC3,PPARGC1A,GK,GPD1,GPD2,HBA1,PMP2,PMP22,PPARA,ROM1,SP2,TCEA1,SYNE1,ARHGAP9,KAT6B" Drug ctd:D003513 Cycloheximide CTD 5.64E-03 1.00E+00 2.95E-02 3.35E-01 91 449 "ADRB2,NR0B1,BBOX1,ANK2,APAF1,AQP4,TMEM263,EIF4G3,BACH1,SEC11C,BID,CFLAR,CALB1,ISPD,RGN,MTMR7,CD38,SOCS6,CHRM1,CLCN3,DNAJB5,CNR1,AKAP6,SLC25A27,AKAP5,CS,CSF1,SOCS5,ST18,SIRPA,ABCC5,DNM1L,EDN1,EDNRA,EDNRB,EGFR,EIF5,ELN,RABEPK,STX2,ERBB2,F3,FGFR1,FHL1,PPARGC1A,CBX1,GPR37,RAPGEF1,NR3C1,GRM5,PTPN5,SYNPO,HNRNPK,IGF1,IL6ST,MBP,MSR1,NEFH,NFE2L2,PDCD2,PENK,ABCB1,SERPINE2,PLP1,PPP3CB,PRKCB,PRKCZ,MAPK3,MAPK7,PTN,RET,ARMC5,FBXW7,S100B,SGK1,ST8SIA1,SLA,SLC2A5,SLC22A4,SPTAN1,KANK1,TAC1,TACC1,ACSL6,KIAA0930,TJP1,VLDLR,VSNL1,RICTOR,NLRP3,SOCS4" Drug CID005488798 NSC609395 Stitch 5.67E-03 1.00E+00 2.96E-02 3.37E-01 11 31 "TUBD1,TUBB3,TUBB4A,TUBA8,GPR162,TUBA1C,TUBB2B,STMN1,TUBB2A,TUBB1,TUBA1A" Drug CID000134780 pomalidomide Stitch 5.67E-03 1.00E+00 2.96E-02 3.37E-01 11 31 "PHF12,FCGR1A,FGF1,NELFCD,TNFAIP8L3,IL12A,ITGAM,PDE4B,PDE4D,SELL,TNFRSF1B" Drug CID000001642 AC1L1BWR Stitch 5.69E-03 1.00E+00 2.97E-02 3.38E-01 21 76 "BCS1L,SCARB1,CHGA,CHGB,CLTB,ERBB2,ADGRV1,ST6GALNAC3,GLRB,GRIN2C,GRIN2D,NR3C1,HMX1,SCG3,RBBP8,SALL1,SMARCA4,MLST8,CRB1,SMARCAD1,SCG2" Drug 3283_DN Digoxin [20830-75-5]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "APAF1,CFLAR,TAOK2,CLCN3,ARMC8,SMARCAL1,MICAL2,DZIP3,ZNF337,GIT2,ZBTB24,RHOBTB1,ANKRD46,SIDT2,EGR3,EIF5,ARMCX1,GPR19,HPS5,JAK2,PDCD2,PIK3R1,NLE1,ZSCAN32,PTPRE,TMEM231,RAD51D,ROBO1,ZC3H14,MAP6D1,TRAPPC13,ZFP30,ZNF302,CEP68,ZC3H4,ARHGEF9,ANKRD12,TBL1X,TRIM2,ZNF23,ZNF32,ZNF184,ZNF248" Drug 7402_DN Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "GRAMD1B,ADRB2,C1QTNF1,BIN1,ANK3,APC,APP,MARCH3,ALDH4A1,BCL7A,MYRF,CCNT1,NMT2,QKI,HOMER3,HAPLN1,CSF1,PPP6R2,FEM1B,ELAVL2,SPEG,PDLIM5,FYN,TMEM8B,HAS2,IL6ST,LIG4,MAPT,MEIS1,ZNF862,NASP,ZDHHC14,RGS10,ZNF671,SH3GL2,AMBRA1,SHANK2,SLC22A4,DNMBP,FBXW11,TCF4,NSD2,UPF3A" Drug 1656_DN 15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "PPFIA3,APP,MPDZ,BCL2L2,SRSF11,RAB26,AKAP12,NCOR1,MICAL2,DZIP3,CTNND2,PPP6R2,RHOBTB1,PARD6A,SGSM2,SIDT2,EPB41L1,DLC1,KAT8,FGFR3,EVL,GHR,PSRC1,GPR37,BRINP3,JAK2,KCNJ3,MEIS1,PDE3B,PIK3R1,PKIA,SYTL2,RAB5B,RET,FBXO11,SMTN,ERC1,TROVE2,POGZ,TACC1,WWC1,TRPS1,SSBP2" Drug 3244_DN Corticosterone [50-22-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "CFLAR,SCAPER,CA12,QKI,ABCG1,GREB1,RHOBTB1,DSCAM,RASGRP1,EGR3,DLC1,FGFR1,EFCAB2,COPS8,KCNMB4,TJAP1,JAK2,KCNF1,MAPT,MPP2,PIK3R1,SMOX,CNNM2,ELOVL2,RBBP8,RET,SLC25A36,RPS6KA2,MAP6D1,SBF1,SGK1,FAM102A,ARFGAP1,POGZ,FCHO1,MAPK8IP3,EXOC7,KAT6B,HIRA,VAV2,WIPF1,FTSJ1,SEMA3B" Drug 5598_DN "ICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "ASPHD1,ALCAM,LTBP4,MRTFA,APBA2,PPFIA3,CDC14B,MARK4,CA12,CAMK2G,HOMER3,GREB1,PARD6A,RASGRP1,SIDT2,EGR3,RRAGB,EZH1,GPR153,JAK2,KIF5C,NF1,PDE3B,SMOX,SAMD9,RAB3A,RET,RGS3,WLS,SGK1,PPP1R9A,SYBU,SLC1A7,KDM4C,THSD1,ASTN2,KAZN,KIAA0930,CABIN1,CDK20,PLPPR2,ZNF45,SEMA3B" Drug 4989_DN Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "ADCY6,KRIT1,SRSF11,QKI,ARMC8,ENTPD4,APPL1,KIAA0586,DSCAM,EML1,TUBD1,COQ7,FGFR3,ANKFY1,PRRC2B,MAP4,MAPT,AFF1,NASP,PDE3B,RETREG1,TNPO2,PTK2,RBBP6,CLIP1,ITSN1,DHX30,SMTN,INTS9,CLASP2,CEP68,JMJD6,CAMSAP2,FAM208A,PDLIM2,TMPO,KCTD2,TP53BP2,RBFOX2,METTL3,SMUG1,ZMYND8,MVB12B" Drug 868_DN 5182598; Down 200; 25uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "ADD3,MTUS1,MARK4,ZBTB10,CAST,CBFA2T2,PARD6A,PCOLCE2,EPB41L1,EXTL2,ARMCX1,DLC1,TESK2,SEMA4D,FYN,GPR37,ARHGAP12,MATK,NEK1,SLC11A2,GPSM2,PRKAB2,PKIA,ELOVL2,CEP97,RIC8B,ZC3H14,SGK1,SLC15A2,SMARCC2,DOP1A,UHRF1BP1L,ITPRID2,TACC1,FAM208A,TRIM2,TIAM1,BEX4,TPM1,NPL,CADM1,XRCC4,NAV2" Drug 6975_UP prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.69E-03 1.00E+00 2.97E-02 3.38E-01 43 187 "ADRA1D,AMT,BCAS1,SEMA4G,N4BP2L1,CFLAR,MTMR3,BTRC,NEURL1,SLIT2,CLU,QKI,PDE4DIP,TMCC2,MED12,CNNM1,OPTN,EIF4G2,STX2,FHL1,OGA,GAB1,SRCAP,HNMT,MAPT,MDFI,GIT1,ADAM22,PRKAR1B,KCTD17,CPEB3,SYBU,ZHX3,INKA2,VPS13A,TACC1,TRIM2,RPGRIP1L,TK2,CDK20,CHST5,SEMA3B,SSPN" Drug CID000005734 zonisamide Stitch 5.78E-03 1.00E+00 3.01E-02 3.43E-01 18 62 "ABAT,ASIC1,CACNA1I,CACNA1G,CA4,CA8,CA12,ASIC3,NOS1,PTCH1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SLC6A11,SCN3B,CA14" Drug CID003292433 AC1MMVSM Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "ARSE,GPRASP1,BLOC1S6,DMD,EFS,NR3C1,IGFBP1,NCAM1,PORCN" Drug CID000174488 Lowicryl HM20 Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "SLC4A4,SLC4A7,SLC4A8,BOC,GAP43,MBP,SCN2A,SLC6A1,SYP" Drug CID001356208 AC1LXO3B Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "NCOR1,FOXM1,IGF1,DISP2,IL6ST,PTCH1,KIF7,KIF27,HHIP" Drug CID000341375 NSC-373301 Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,ADHFE1,TUBB1,TUBA1A" Drug ctd:D010716 Phosphatidylinositols CTD 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "ADRA1B,CHRM1,EDN1,EDN3,GNAS,GRM5,MAPK3,PTAFR,RGS4" Drug CID003035871 fluorescein-colchicine Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,ABCB1,TUBB1,TUBA1A" Drug CID000129239 "2,3,4-TCB" Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000130739 IKP104 Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000006858 "3,4,5-trimethoxybenzaldehyde" Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TBL1X,TUBB1,TUBA1A" Drug CID000003168 droperidol Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "ADRA1D,ADRA1B,CACNA1B,DRD1,HTR2A,KCNH2,CCDC80,TAC1,HHIP" Drug CID000100176 NSC355636 Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000125548 "2,3,4-tabp" Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000003118 disulfoton Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "ACHE,APC,BCHE,CHRM1,DCTN1,ATP8A2,CLDN11,AP1AR,TBL1X" Drug CID000097865 N-acetylcolchinol Stitch 5.80E-03 1.00E+00 3.02E-02 3.44E-01 9 23 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID006914631 AC1OCACU Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ATP6V0A1,CALM1,KRIT1,FOXG1,PTPA,RNH1,CCDC88A,BEX1,SYNE1,TST" Drug CID000031958 AC1L1MOZ Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ASIC1,ASIC3,NKX6-2,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,ST8SIA2" Drug CID000121872 Sch 39370 Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "AGT,EDN1,EDN3,EDNRA,EDNRB,NPPA,PENK,TAC1,TAC3,TACR1" Drug CID000178028 NSC D-669356 Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID000007627 p-MB Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "RGN,TAOK2,DTNB,PIPOX,P2RX7,SALL1,SLC1A2,SLC1A3,MLC1,GPR161" Drug CID000005416 krypton Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "CARS,EPHA5,FGF1,DNER,MSTN,NHLH1,NODAL,PMP2,PSD,LEFTY2" Drug CID000001585 AC1L1BSF Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ADARB2,ADORA1,ADORA2A,ADORA3,PTPN5,HP,HPR,MATN3,EFHD1,TAC1" Drug CID000022478 IBDU Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ADRA1D,ADRA1B,EDNRA,EDNRB,P2RY1,PRKCB,PRKCG,SST,SSTR1,SSTR2" Drug CID000447834 AC1L9LAE Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,AGT,NR3C1,INSM1,MBNL1,PTPRN" Drug CID000003506 AC1L1G38 Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 10 27 "ATN1,SEMA4D,SDCBP2,NR3C1,NEGR1,KCNK1,MAT2A,RNH1,SST,DPYSL5" Drug 7376_UP Salbutamol [18559-94-9]; Up 200; 16.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-03 1.00E+00 3.03E-02 3.45E-01 42 182 "CACNA1G,IL33,CALB2,MAP7,ARHGAP22,WHRN,CREM,AKAP12,CTH,PITPNC1,DPH1,EFNA3,COQ7,FGFR1,DENND2A,ERAP1,C1QL1,GNAL,GNG3,SHISAL1,KCNN1,MMP16,MYO7A,PDE4D,SMOX,PMP22,TNPO2,FA2H,PRPH,SIDT1,PTHLH,FAM120C,TMEM231,GSTCD,ASAP3,RBM34,CDK19,TBL1X,DNAH7,CABIN1,ZKSCAN5,DPF3" Drug 6990_UP 15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.83E-03 1.00E+00 3.03E-02 3.45E-01 42 182 "BIN1,BCAS1,ARHGDIG,RGS20,SCAPER,CREM,SIPA1L1,CTH,MED12,DTNA,PHF20L1,EIF5,F3,ZNF589,FECH,C1orf61,EFCAB2,INPP5K,MALT1,GLS,KIF5C,MAP4,MAPT,MBD1,MDM4,NAP1L2,NUMA1,PDE3B,PAQR6,SBF1,HSPA4L,SH3BGR,ZNF365,PEX26,TTBK2,PLCB1,TRIM2,DOCK9,UBE2H,REEP1,ZFAND5,EVI5" Drug 1280_UP Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.83E-03 1.00E+00 3.03E-02 3.45E-01 42 182 "GRAMD1B,FAM131A,STX16,SLC25A14,CD86,CD38,CHN2,QKI,VCAN,SLITRK5,PPP1R16B,DOCK4,DBT,DTNA,FCF1,SIDT2,FAM13A,LPAR6,OGA,ARFIP1,TXNL4A,NR3C1,ITGAV,MEF2C,NFYA,SLC11A2,OLR1,PDE3B,PDE4B,PDE4D,CCSER2,STRN3,PTK2,SLC12A2,EPB41L3,NXT2,ANKRD12,FBXW11,FLRT2,BEST1,ZNF45,NLRP3" Drug 3699_UP Alexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.83E-03 1.00E+00 3.03E-02 3.45E-01 42 182 "SEMA7A,SLC2A11,FGF17,BMP7,CACNA1G,CARS,CBS,VAX2,TCEAL2,CREB5,AATK,CSF1R,CTH,MFAP3L,ARNT2,DTNB,HEYL,EGFR,DLC1,OLFM1,CAMSAP1,AGAP2,GALC,GAP43,ATP8A2,ALDH1L1,GRIA4,MT1M,LYRM9,NNAT,ODF2,P2RX7,KCNK10,SMOX,RGS4,CPEB3,SLC11A1,IZUMO4,PCDHGA10,TNS1,SEZ6L,JPH3" Drug CID000020392 monomethyl phthalate Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 37 156 "MTMR7,CDO1,CS,PLCXD3,DMPK,DRD1,PIPOX,DNER,MSTN,GFER,GHR,PLCD4,GSN,PTPN5,HP,HPR,IGF1,ITPKA,ITPKB,NAP1L1,PDE3B,GNG2,PIK3C2A,PIK3CD,PIK3R1,PLCB2,PLCD1,PSAT1,APTX,PTHLH,RASGRF1,SHMT2,PLCB1,PIK3R5,TTPA,RNF103,HPS4" Drug CID000445754 nM-1 Stitch 5.83E-03 1.00E+00 3.03E-02 3.45E-01 37 156 "ADCY5,ADCY6,ADCY8,ADCYAP1R1,ADORA2A,AGT,CACNA1B,CACNA1E,CACNA2D1,CCK,CDC42,CHRM1,CNR1,EDN1,EDN3,EDNRA,EDNRB,B3GAT1,CRCP,GLRB,GRIK4,MUM1,IGF1,KCNA6,KCNN2,KCNN3,MT3,NRGN,OPRL1,PRKCB,PRKCG,RYR3,SST,TAC1,TAC3,TACR1,VIPR2" Drug ctd:D004737 Enflurane CTD 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ALAD,CACNA1I,GABBR1,GABRA1,GABRA2,GABRB1" Drug CID000004877 1NaPP1 Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GRIA1,GRIA2,GRIA4,PIK3CD,RELN,LRP8" Drug CID004369390 1vyq Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP2C1,SLC6A7" Drug CID000162908 pyrenedecanoic acid Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ABHD6,CNTN1,CYBB,F3,MAT2A,NETO1" Drug CID000197626 U-93631 Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000197690 SB-205384 Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000124866 DFT-D Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "CHGA,ENO2,FCGR3A,B3GAT1,GFAP,SYP" Drug CID000008095 EGEEA Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "CSF1R,MYOZ2,POLL,CNTN3,CLSTN2,ITPRID2" Drug CID001201426 6-chloropurine Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ADORA2A,BOC,RNASE1,SALL1,TCF12,SYNE1" Drug ctd:C434247 diphenylditelluride CTD 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "PPP1R1B,GFAP,NEFM,NEFH,MAPK3,MAPK8" Drug CID000119330 anthrapyrazole Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "CLTB,LSS,ABCB1,MAPK8,MAPK9,MAPK10" Drug CID005049868 [Sar9]-Substance-?P Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ELAVL3,TUBB4A,B3GAT1,TAC1,TAC3,TACR1" Drug CID005327863 Go7874 Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "AMPH,SNAP91,DNM1,DNM2,DNM1L,PPP3CC" Drug CID000129572 AC1L2VU3 Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1E,TRH" Drug CID000038668 doxefazepam Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000003563 haloxazolam Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000003494 glycopyrrolate Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ACHE,BCHE,CBR1,CHRM1,SNAP91,TRAPPC9" Drug CID005280666 chrysoeriol Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "SEMA6A,ABCG2,ATN1,FDFT1,SEPT4,TMEM121" Drug CID000055263 piroximone Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "ADRB2,APP,ALDH7A1,PDE2A,PDE3A,PDE3B" Drug CID000071228 razobazam Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 6 12 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000004629 oxotremorine-M Stitch 5.89E-03 1.00E+00 3.06E-02 3.48E-01 22 81 "ACHE,BCHE,CHRM1,CHRNA4,CHRNB2,PLCXD3,DMPK,TNK2,FYN,GNAS,PLCD4,KCNJ3,KCNK3,KCNQ2,KCNQ3,MAP4,MT3,PLCB2,PLCD1,PLCB1,SYNE1,TNS1" Drug CID000130021 CGP 36742 Stitch 5.90E-03 1.00E+00 3.06E-02 3.48E-01 14 44 "ABAT,CHRM1,DBN1,DLG4,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,PDYN,SLC6A1,SST,VGF" Drug CID000031762 dihydro-beta-erythroidine Stitch 5.90E-03 1.00E+00 3.06E-02 3.48E-01 14 44 "ACHE,BCHE,CHRM1,CHRNA4,CHRNB2,DMPK,GPHN,GRIK1,GRIN2C,GRIN2D,CCDC80,NPY,VSNL1,PORCN" Drug CID006433489 escina Stitch 5.90E-03 1.00E+00 3.06E-02 3.48E-01 14 44 "ANXA7,CALM1,CHRM1,MYL6B,DMPK,EDN1,RND1,MYLK2,MYL3,PKM,RYR1,RYR3,NSFL1C,MLC1" Drug CID000007153 mecoprop Stitch 5.90E-03 1.00E+00 3.06E-02 3.48E-01 14 44 "SERPINA3,ADRA1B,ADRB2,CHRM1,DCC,DRD1,EFS,HTR2A,HTR5A,PDCD2,WLS,CLSTN2,ITPRID2,NELFE" Drug CID000243583 NSC53670 Stitch 5.90E-03 1.00E+00 3.06E-02 3.48E-01 14 44 "ACHE,APP,ATP6V0A1,BCHE,QKI,KHDRBS3,GRIA1,GRIK5,GRIN1,HNRNPK,MAG,KHDRBS2,SAFB,NUP214" Drug 3862_DN Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ADRA1D,AMH,APAF1,CDK13,CA4,CALB2,RAB28,CRY2,PDE4DIP,NOS1AP,DMPK,EFNA3,ELN,HSD17B14,STON1,SPACA9,INPP1,MATK,MMP16,ADAM22,MYO7A,NDUFA5,NPPA,NPTX1,NTRK2,PCDH9,RELN,PTPRE,RAD52,ENOX1,RGS10,NEK11,EMID1,SLC6A8,SHANK2,UNC5B,TSPYL2,KIAA1107,AHCYL2,CHST8,HEY2,LAT2,ZFP37,EVI5,PLSCR4" Drug 2455_DN Pirenperone [ 75444-65-4]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "RALGAPA1,ADRA1D,KIDINS220,PLA2G6,BIN1,APOC1,TAOK2,STOML1,ABCG1,DOCK4,DGKG,EFNB3,PLEKHA1,ENO2,RASGRP2,CAMSAP1,FOXG1,GABRA2,GATM,ZNF276,MAP4,NUMA1,OLR1,PDE4D,PRKAR1B,MAPK10,CNNM2,RAB3A,SCG5,FAM102A,EPN2,SMTN,FAM214B,SLC6A8,SLC11A1,MYH15,ZHX3,IZUMO4,RBM26,CAMSAP2,OBSL1,CHST8,LMF1,CLIP2,PCBP4" Drug 1101_DN catechin; Down 200; 11uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG3,APC,CDK10,NCOA1,MTMR2,ZNF337,SPATA2,COPS7A,SGSM2,EXOG,SUGP2,MBNL2,FGFR1,NBEA,TACC2,MALT1,PRRC2B,KIF2A,KIF5C,MBP,SETD4,OGDH,OGG1,PDCD2,SSH1,RC3H2,MRPS18A,ROBO1,MAP6D1,SAFB,ATXN7,GALNT10,SFPQ,SUPT20H,CHD9,DHX30,SPTAN1,CDK19,TRIM2,DOCK9,OBSL1,NR2C2,TRIO,TSN,ZNF24" Drug 7456_DN Chlorzoxazone [95-25-0]; Down 200; 23.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AK2,NCOA1,ATP6V0A1,MPDZ,SYNJ2,REPS2,RAB28,HINFP,CTNND2,PPP6R2,DBT,SGSM2,DNM1,MED12,DTNA,PLEKHO1,PRKAG2,SEPT9,SLC2A6,GIT1,SMIM7,FA2H,CYBC1,C1orf109,RALGDS,GTDC1,ROBO1,ITSN1,AMBRA1,PEX26,EPN2,ZSWIM8,SPART,ITPRID2,NXT2,ARHGEF9,VPS13A,TACC1,TBL1X,TRIM2,RBFOX2,LMF1,ZBTB14,REEP1,GDPD5" Drug 415_DN nordihydroguaiaretic acid; Down 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AK2,ALAD,SYT13,CDK10,PDXK,NCOA1,SYNJ1,CAMK2G,JAM2,TAOK2,PCYT1B,CRY2,CLIP3,GAPVD1,RBM12,F5,SCARA3,LILRA2,GRM1,RNFT2,ITPKB,KCNJ5,MGAT3,ADAM22,NRGN,OMG,RETREG1,SIDT1,PEX5,SUSD4,SLA,IFT122,HECW1,LHPP,CLSTN2,ZC4H2,CEP68,ATP13A2,TRPC1,CA14,FLRT1,MAP3K12,GDPD5,SNX27,MVB12B" Drug 7251_DN Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,OGT,CDC14B,MTMR9,RIPK1,MPDZ,CFLAR,CLCN4,NIPBL,SLC4A7,CREM,ARHGAP32,ZNF804A,EZH1,DLC1,TACC2,CINP,MPP6,TRAF3IP2,GLS,NR3C1,HNMT,HSF2,IFI16,JAK2,KHK,ZNF862,OGG1,CCSER2,SLC25A23,MAPK3,BSDC1,KIRREL1,URGCP,IFT122,KDM4C,POGZ,TRIM2,METTL3,TRPC1,ZNF45,SNX27,FIP1L1,MPPE1,TIGD6" Drug 3276_UP Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APBA2,CDC14B,PLA2G4C,ASPH,CADM3,ARHGAP33,WHRN,DZIP3,RIMS3,KIAA0586,CNNM1,SIDT2,SORBS3,ENO2,VPS13B,FHL1,GABRA2,GLYR1,STON1,GPER1,ICA1,KCNH2,KCNN2,LMO2,MDM4,MYCN,ZNF862,NPR2,CEP41,MAPK7,MAPK8,PRPH,PTHLH,C1orf54,BSDC1,TRIM68,SUPT20H,ASAP3,LIMCH1,SMG6,THRA,CDK20,BCL2L13,VLDLR,EMSY" Drug 6630_DN Fursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "KIF1A,CAMK2G,CBFA2T2,SCARB1,LARGE1,SOCS6,CHM,PLEKHB1,B4GALT6,PICK1,IQCK,VCAN,SLITRK5,DZIP3,CTIF,FEM1B,EGFR,MBNL2,PLEKHO1,COQ7,ZNF549,FYN,GAD1,INPP5K,MDFI,MDM4,PPARA,WDR25,PID1,RAD52,FBXW7,RPS6KA2,AMBRA1,RAP1GAP2,DDN,MAPK8IP3,ELOVL4,WWC1,CRTC1,AHCYL2,TMEM121,TK2,ZBTB14,MAP3K12,SEMA3B" Drug 7501_DN Suramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BIN1,CDK13,ATP2A2,ADAM15,FOXN3,CHRNB2,CLU,TPP1,HOMER3,MYRIP,SH2B1,NCOR2,DLG3,DTNB,FCF1,CELSR3,COQ7,ANKFY1,DLL3,USP19,GLS,KHK,MX1,ZNF862,PDE1C,CCSER2,EPN1,MAPK8,PTN,PEX5,CCDC40,RAD51D,RAD52,RALGDS,ARHGEF10L,IL17RB,ZNF821,MRAS,ZNF415,ATP10B,ARHGEF9,ASTN2,TNS1,TRIO,VGF" Drug 1170_UP clozapine; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AP2A2,APBB2,APP,ARHGDIG,ATP6V0A1,RIPK1,ADAM15,KRIT1,CDH10,HOMER3,CREM,MAML1,ZEB2,KIAA0753,RCAN1,DTNA,EGR3,SRPK3,VPS13B,COQ7,EPS8,KIAA1109,FHL1,ERAP1,GLYR1,LILRB4,SLC2A6,TJAP1,SCAMP5,SLCO1C1,NINJ2,MINDY2,PTAFR,RGS3,ITSN1,BTBD7,TMCC1,KIF1B,IQSEC2,ZBTB43,SEPT8,MLC1,TCF7L2,TNNT1,TNS1" Drug 7240_DN Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASPHD1,ADD3,AP2A2,OSBPL1A,FAM131A,ATM,CFLAR,REPS2,HOMER3,PDE4DIP,CTH,GREB1,GIT2,DBN1,FBXL5,SIDT2,EGFR,PLEKHO1,ZNF589,DPYSL4,COPS8,KCNMB4,GRB10,BTN2A1,TJAP1,KCNJ3,MAP4,LYRM9,PCDH9,PDPK1,MBOAT7,PTCH1,RIPOR1,CEP97,GTDC1,FOXRED2,SLC1A7,SMTN,WDTC1,EMC1,RBFOX2,TRPC1,RPRM,VGF,MICAL1" Drug 7013_DN Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,CDC42BPA,PPFIA3,NUMB,CDK5R1,MTMR2,LHX2,RAB28,ZFYVE9,SLC4A7,CHD1L,PPP6R2,GIT2,RABGAP1L,ARNT2,DSCAM,TESK2,PDLIM5,ERAP1,GART,MSL3,DHX35,MAP4,MYO9A,NFYA,OGG1,OPA1,OXTR,TNPO2,TMEM231,ARHGEF10L,DCUN1D2,RXRA,HSPA4L,ITSN1,PEX26,MAPKBP1,CLASP2,MTCL1,EXOC7,FBXW11,SIK3,LMF1,ZNF45,URM1" Drug 7363_DN Griseofulvin [126-07-8]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "EP400,APP,ARNTL,ALDH4A1,RIPK1,CFLAR,SCAPER,ARHGEF2,CNOT8,CLCN3,KIAA1549L,TPP1,HOMER3,BAG4,OSBPL3,SLITRK5,KIAA0513,EDNRA,FCF1,EGFR,COQ7,ST3GAL6,SCARA3,CINP,ATP2C1,INPP5K,HTATSF1,MT1M,PDGFRA,SLC25A23,MAPK7,SEC61A2,ZNF671,ATXN1,PPP1R9A,FAM214B,SHANK2,NMNAT2,CAMTA2,NCDN,KIAA0930,TRPC1,MPPE1,PLSCR4,AAAS" Drug 376_UP raloxifene hydrochloride; Up 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ALAD,SPOP,GAS7,SLC4A4,ATP2B1,INA,ZMYM4,RAB28,CLCN3,COL4A5,CHD1L,PDE4DIP,MBNL2,ELAVL4,LRRC23,EFEMP1,TESK2,FAM49B,GHR,GJB1,GLYR1,ZNF638,GRB10,ARHGAP19,ITPKB,NELL2,PLCD1,PPM1B,PRKAR1B,GON4L,RBBP6,RGS3,COA1,CDK5RAP2,SMARCD3,PALLD,POPDC3,ANKRD12,TRIO,UBE3A,KLC2,ZNF74,MARCH8,PHTF2,JMJD1C" Drug 3703_UP Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "KIDINS220,CCDC181,ATP6V0A1,RUNX1T1,SLC24A2,DNAJB5,ARHGEF4,RIPOR2,MAGI2,ST3GAL6,FGF1,FGFR1,HPCAL4,GAB1,ATP8A2,GNG3,ADAMTS13,HTR2A,KCNF1,KCNH2,KCNN1,MMP17,MYT1,NRCAM,NTRK2,PACSIN1,PPP1R1A,RGS4,RGS12,PNMA8A,DOCK10,SLC1A6,SCN3B,MLC1,ARC,SYT1,TMOD1,TNS1,TRIO,TRPC3,PDIA2,OSBP2,LAT2,SPHK2,SLC17A7" Drug 6231_UP Racecadotril [81110-73-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AP2A2,SRPX,TRMT9B,AMT,APC,SHROOM2,CCKBR,TPP1,FAM189A2,MAP4K4,PPP6R2,MFAP3L,RABGAP1L,TMCC2,DLG3,E2F5,ING4,F5,ACSL4,ZNF589,C1orf61,MALT1,TDRKH,GRM1,DHX35,IL6R,KCNJ3,NUCB1,PRODH,SAMD9,ZSCAN32,NEK11,SH3BP2,EPN2,RAB3GAP1,ZBTB43,MAPK8IP3,EXOC7,PCDHGA10,SLC44A1,CABIN1,CADM1,VGF,VIPR2,MPPE1" Drug 2094_DN Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "CDC14B,ARRB2,BCL2L2,MYRF,FOXN3,NIPBL,HOMER3,ARMC8,HINFP,USP6NL,KIAA0513,INTS1,DBT,HP1BP3,RUSC2,C2CD2L,VPS26C,F3,BAIAP2,GFER,KIF3A,INPP5B,NACA,PFKFB2,RC3H2,RIPOR1,RAB3A,SEC61A2,CCDC25,CCDC88A,ELMO2,SLC20A2,FNBP1,SS18,NCDN,CEP68,TCF7L2,TSC1,HIRA,LMF1,WIPF1,ZNF189,VPS35L,ACTR3B,AAAS" Drug 7243_DN Urosiol [128-13-2]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,APLP1,MTMR9,RAB28,IQCK,ABI3BP,PPP6R2,KIAA0753,PARD6A,SGSM2,SLC12A6,EIF5,EML1,SPEG,FECH,ANKFY1,TRAF3IP2,EML4,NR3C1,RNFT2,MITF,SETD4,SMIM7,POLG,SYTL2,ATG16L1,CSRNP3,SMARCC2,PDZD2,NMNAT2,UHRF1BP1L,ZBTB43,NCDN,DIP2A,DNMBP,ARHGEF12,TMEM121,METTL3,TRPC1,TRPM2,XRCC4,PMEPA1,FIP1L1,TIGD6,AAAS" Drug 5335_UP Neostigmine bromide [114-80-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AK2,ALCAM,CDC42BPA,APC,CDC14B,NCOA1,ATM,SCAPER,NMT2,QKI,CREM,ARHGEF10,DBN1,SMG7,RABGAP1L,DSCAM,FCF1,F5,ANKFY1,ARFIP1,GNAO1,BTN2A1,HNMT,DIPK1A,MAP4,MDM4,NFYA,PC,PDE3B,PDE4A,MINDY2,PRKAR1B,NKAIN1,ITSN1,ANKRD6,NXT2,EXOC7,EHBP1,PSD3,TRIO,ZMYND8,ZBTB14,NDRG4,MAP3K12,MPPE1" Drug 2980_DN Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BIN1,DNAH17,SLC4A4,ATP6V0A1,BMP7,RAB33A,NMT2,CPS1,SIPA1L1,EDRF1,DNAJC6,RUSC2,SIDT2,SCML2,FHL1,TRAF3IP2,SRCAP,GPR19,PCLO,GRM1,IL11RA,MEF2C,SCAMP5,MX1,NPR2,NRCAM,PFKFB4,NLE1,MAPK8,PTAFR,ZCWPW1,SYNDIG1,PAQR6,RBM26,RAP1GAP2,KIAA1107,TCF7L2,TMOD1,TRPS1,UBC,FLRT2,LMF1,ZNF32,ATP6V0E2,PRDM2" Drug 2816_DN Picrotoxinin [17617-45-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABHD6,APOC1,ST3GAL5,SCAPER,BTRC,CCNT1,SCARB1,ZFYVE9,DNAJB5,QKI,PDE4DIP,SIDT2,SCML2,KIAA1109,FGFR1,BAIAP2,GAA,B4GALNT1,MALT1,TXNL4A,CACFD1,ATXN2L,HNMT,INPP5B,ITPKB,JAK2,NUCB1,SSH1,PTPRE,RIPOR1,ATG16L1,BSDC1,REV3L,RGS10,SMTN,SLC22A4,COA1,MCF2L,TIAM1,TMOD1,KCTD2,TRIO,HPS4,MPPE1,EPM2A" Drug 6196_DN fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,BIN1,PKP4,APC,FAM131A,LDLRAD4,INA,RCHY1,CRY2,DOCK4,DTNA,RBM12,FAM13A,ABI2,IRAK4,NCALD,FOXG1,PRELID3A,CGREF1,FYB1,GAA,ERAP1,TJAP1,ARHGAP12,MAP4,PENK,RC3H2,MBOAT7,PILRA,BCAS3,WDR25,PTK2,PID1,ZDHHC14,SLC11A1,KDM4C,DDN,FCHO1,STX1A,VAMP1,KAZN,TGFBR3,TMOD1,TNNT1,VIPR2" Drug 5361_UP Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,C1QTNF3,APC,LGR5,ARHGDIG,MARK4,SCAPER,CBR1,QKI,COL9A2,SIPA1L1,PDE4DIP,ARHGEF4,MFAP3L,CDON,ATN1,FEM1B,LRRC23,NCALD,BAIAP2,FHL1,DPYSL4,TBR1,RASSF8,KCNMA1,MAP4,MMP16,MPP2,ZNF862,NEK1,CNNM2,GON4L,RGS10,SEC14L1,ITSN1,PPP4R3A,BTBD7,LIMCH1,ZBTB43,SEMA4A,EXOC7,CHST8,TRIO,TSC2,GDPD5" Drug 1377_UP Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG3,APAF1,MTMR2,WASF1,CAST,ARHGAP33,DAPK3,G3BP2,ANKRD46,ABI2,VPS26C,TRMO,STAU2,OGA,GLYR1,NR3C1,INPP5B,ITGAM,KCNN2,IPO5,MBD1,NAP1L1,NFE2L2,ENPP2,PLEC,FTO,SLC25A23,ZNF426,GON4L,RBBP8,CLIP1,ATXN2,HSPA4L,SGK1,ITSN1,FUZ,SEC31A,MAPKBP1,ZSWIM8,DBNDD2,TSPYL2,ITPRID2,TCF7L2,EVI5,WIPF2" Drug 4280_UP Tropicamide [1508-75-4]; Up 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APAF1,APBB2,ZSCAN18,BMPR1B,FUBP1,CACNG1,CBLN1,LARGE1,CLCN4,SNCAIP,CTNND2,EDRF1,DBT,DCT,EDN1,CNNM1,EFNB3,MRNIP,RASGRP2,IGSF6,FGF12,FGFR3,GFRA2,CSDC2,MSL3,GNG4,LILRA2,ADAMTS13,OPCML,PURG,PKN2,PTPRB,FAM120C,CCDC40,RASGRF1,GAL3ST4,RGS4,FOXRED2,HKDC1,DDN,SS18,SYP,CRTC1,TPM3,EPM2A" Drug 5335_DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABR,SLC12A5,SLC4A4,SYNJ2,TAOK2,RAB28,VAX2,HOMER3,CREM,SIPA1L1,PDE4DIP,EGFR,ANKMY1,F3,SCML2,EFCAB2,CGREF1,NR3C1,INPP5B,SCAMP5,CNOT4,NUMA1,RETREG1,PLXNB1,PRPH,WDR25,RAB3A,RAB3IL1,ABLIM3,WDTC1,UHRF1BP1L,KDM4C,ERC1,SPTAN1,CAMTA2,NCDN,MAPK8IP3,SEMA4A,CABIN1,CDK20,TRPC1,REEP1,PCBP4,MVB12B,SMIM8" Drug 6488_DN Bacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,ALCAM,BIN1,EPB41L5,SEMA4G,PLA2G4C,ALDH7A1,CCNT1,BAG4,GIT2,DBT,JAKMIP2,SMG7,PARD6A,RABGAP1L,DTNA,CNNM1,EFNB3,ATP8A1,PDLIM5,FAM49B,GPR37,ITPKB,KCNH2,MAP4,MAPT,MID1,NF1,SLC11A2,MAPK7,FAM120C,KHDRBS2,ZC3H14,RPS6KA2,EMID1,SMTN,SLC22A4,SS18,NXT2,ARHGEF12,TMOD1,HIRA,CADM1,CLDND1,MPPE1" Drug 5117_UP Bumetanide [28395-03-1]; Up 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "DNAH17,SLC4A4,ATP6V0A1,ADAM23,CFAP410,CHM,CHN2,DNAJB5,RGS6,RUSC2,SMG7,RCAN1,DTNA,TOM1,TNK2,COQ7,SORBS1,ZNF44,GAD2,GART,GLUL,NUDT21,VWA5A,MDM4,MGAT3,KITLG,AFF1,AFDN,NOS1,PALM,MINDY2,SAMD9,TMEM231,RAD52,KHDRBS2,NEK11,RASA3,DZIP1,NXT2,MAPK8IP3,PLCB1,KAZN,ZEB1,TK2,LAT2" Drug 4576_DN Ethamsylate [2624-44-4]; Down 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NME5,MARK4,CFLAR,CACNA1A,PLEKHB1,TAOK2,TPP1,NIPBL,VCAN,RUSC2,PHC2,CNNM1,SIDT2,EFNA3,IRAK4,EN2,TUBD1,DMTN,ERCC2,SYT17,ZNF276,GLRB,STON1,NDP,NDUFA5,MBOAT7,RIPOR1,RAB5B,SUGCT,RPS6KA2,SH3BP2,KDM4D,SHANK2,COA1,SMARCD3,TMCC1,CAND2,ZBTB43,ATP11A,EXOC7,TCF4,CABIN1,LMF1,WIPF1,LAT2" Drug 524_UP nordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APAF1,ARRB2,MARCH3,SLC4A4,ATP6V0A1,ARHGEF2,ARHGAP33,CLCN3,IFFO1,RIMS2,GIT2,G3BP2,ATN1,TNK2,CD320,F3,PTK2B,SEMA4D,NSG1,SYT17,RUNDC3A,SOX21,NXPH3,L1CAM,ADAM22,ENPP2,CCSER2,MBOAT7,POLR2F,PRKAR1B,ACSM5,RBBP6,TMEM206,SEMA6D,FUZ,SLC15A2,CDK5RAP2,SNCA,ZSWIM8,ZC3H13,FAM189A1,R3HDM1,TNR,TUB,USP1" Drug 3569_DN Tropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,MRTFA,PPFIA3,CDC14B,CDK10,PDE8B,CDK5R1,LDLRAD4,FADS2,ABI3BP,CSF1,PDE4DIP,NOS1AP,DAPK3,SGSM2,DSCAM,OPTN,MTSS1L,FAM198B,SCML2,ATP8A1,PRELID3A,MID1,ADAM22,NUMA1,PDE4A,RIPOR1,RAB3IL1,FNDC3A,NLGN1,CCDC88A,ELMO2,BTBD7,TMCC1,RBM34,SEMA4A,SMG6,AHCYL2,ATP13A2,THRA,CDK20,VGF,REEP1,HPS4,URM1" Drug 4126_UP Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,ALCAM,ALK,TRMT9B,ANK1,RASL11B,AZGP1,FGF17,SYNJ1,CBFA2T2,COL9A3,CRY2,TOX,EDNRA,MBNL2,PLXNC1,SORBS3,ELAVL3,SPEG,GAD1,ATF7,GRIK1,GRM1,ATXN2L,KCNMA1,KCNN1,ADAM22,NOS1,NPPA,CLDN11,PCDH9,PLCD1,LRP12,POU3F4,CEP41,CCDC40,FAIM2,SOX2,TNIK,ZSWIM8,SP4,GPR161,TRPC1,UCHL1,SSPN" Drug 6790_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BIN1,ARHGDIG,ARRB1,ATM,SYNJ2,BTRC,CACNA1D,KYAT1,SLIT2,FAM189A2,CSF1R,SDC3,PPP6R2,EDRF1,DTNA,SEMA4D,SEPT9,TXNL4A,GLYR1,MUM1,ATXN2L,KCNJ3,PTOV1,NEK1,PCDH9,RAD52,NEK11,SBF1,SMTN,SHANK2,BTBD7,ZKSCAN3,SMARCA4,EMC1,SS18,PLCB1,MCF2L,TBL1X,TNS2,TRPC1,ZKSCAN5,HIRA,PLPPR2,ZNF74,MPPE1" Drug 6635_UP (+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "LTBP4,AMH,DDO,BACH1,SYNJ1,MYRF,CAMK2B,ARHGEF2,SOCS6,TAOK2,VCAN,PDE4DIP,CNTNAP2,SRGAP3,CHRDL1,DYRK1A,ING4,ZNF391,FGF1,AHDC1,GUCY1A2,KLF12,HPSE2,KCNN1,ADAM22,PALM,PRKAR1B,ELOVL2,C1orf54,IL17RB,PREX2,PEX26,SP2,ZC3H13,SPTAN1,PHLDB1,SEMA4A,MCF2L,TBCEL,CDK20,TPM3,WIPF1,XRCC4,ZNF24,AAAS" Drug 6765_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "RALGAPA1,NDRG2,ADCY6,APLP1,CDC14B,CFLAR,ENTPD6,CDC42,ADGRG1,FADS2,VCAN,DBN1,DMPK,DTNA,ENO2,DENND4A,GPR153,C1QL1,CACFD1,JAK2,KCNN2,MMP16,MOBP,MYCN,NDUFA5,GPR85,NLE1,MAPK7,MAPK8,VPS13C,RAB3IL1,TCP11L1,SH3BP2,FBXO11,FAM214B,PKNOX2,ITPRID2,TBL1X,ARHGEF12,ZNF34,TRIO,SLC30A3,WNK1,MPPE1,EPM2A" Drug 6560_UP Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ACTN1,ARRB2,MAP7,CDH2,PLEKHB1,BAG4,VCAN,CTH,DCAF8,GIT2,DBN1,DBT,SMG7,PHC2,MRNIP,COQ7,EPHA5,FHL1,FAM49B,STON1,PADI2,TAGLN3,NFYA,NUCB1,OCRL,PCDH9,TNPO2,SAMD9,BCAS3,PTN,ZCWPW1,TCP11L1,SMTN,SLC20A2,RBM34,ARHGAP26,ROBO3,PCDHA5,BHLHB9,HIRA,LAT2,UPF3A,EPM2A,ST7,PHTF2" Drug 1431_UP Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,ADD3,BRAP,AK2,C1QTNF3,PPFIA1,PKP4,APBA2,CFAP410,SLC25A14,CD86,ZNF337,KIAA0586,MED12,EEF1A2,EZH1,PDLIM5,ATP2C1,HBS1L,INPP5K,SRCAP,ADAMTS13,JAK2,MEF2C,CNOT4,PALM,CAMKV,PIK3CD,GPSM2,CDIP1,POLG,CCDC25,TMEM156,SH3BP2,RAB3GAP1,MAPKBP1,ZSWIM8,SRPK2,NCDN,GANAB,VPS13A,ANKRD12,TCF4,TMOD1,ACTR3B" Drug 3675_DN Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABHD6,MRTFA,AMPD3,ANK3,APC,APOC1,APP,ARNTL,NCOA1,RASL11B,CDK5R1,HAP1,CBFA2T2,ARHGEF6,IQCK,VCAN,ZNF337,MAML1,DAPK3,RCAN1,SCML2,TRMO,OGA,GPR19,MBD1,OCRL,CLDN11,SERPINI1,RETREG1,RAD51D,RGS10,NEK11,DZIP1,WDTC1,SS18,SYT11,ARHGEF9,ARC,PSD3,XRCC4,ZNF45,NDRG4,WNK1,MPPE1,GAN" Drug 5431_DN Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "SEMA6A,ALCAM,ARRB1,MARK4,SYNJ2,GYG2,MAGI1,CLGN,TAOK2,QKI,C2CD2L,RHOBTB1,OPTN,DMTN,NCALD,FGF12,FGFR1,FHL1,SEMA4D,MPP6,INPP5K,RAB30,GRIK5,HNMT,INPP5B,KCNJ3,KIF2A,IPO5,LIG4,NUMA1,LRP12,ELOVL2,RAD52,GTDC1,ZKSCAN3,ZBTB43,CLASP2,VPS13A,ATP11A,ANKRD12,EXOC7,SLC44A1,KCTD2,TPD52,SEMA3B" Drug 1688_UP Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AK2,PLA2G6,BIN1,APBB2,PPP4R4,SLC4A4,GYG2,HAP1,FOXN3,B4GALT6,QKI,SDC3,GPRASP1,KIAA0513,PARD6A,NR1D2,MBNL2,ELN,ENO2,NCALD,BAIAP2,SPIN1,GNG4,GRIK5,ELOVL5,KIF5C,ADAM22,NAP1L2,NF1,NNAT,NRCAM,NTRK2,NUCB1,PDE4A,RETREG1,PPP2R5C,PPP5C,ARID4A,PPP4R3A,SMARCA4,ZCCHC24,KDM4C,CHST8,ZNF34,PHTF2" Drug 2013_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PLA2G6,AMT,ARNTL,RIPK1,CLDN10,ARHGAP33,TAOK2,CNTN1,CTH,DNM1,SLC12A6,BSCL2,FCGRT,TRMO,CAMKK2,CGREF1,FYB1,SRCAP,RUNDC3A,GLS,GPR12,HSF2,IL6R,LSS,MYT1,NF1,NUCB2,PLEC,RETREG2,MBOAT7,SNRK,RAB3A,AMBRA1,CHD9,SLC11A1,SLC22A4,SLN,MAPK8IP3,CEP68,SYN2,SEMA4A,PDLIM2,ZMYND8,TFIP11,ACTR3B" Drug 2194_DN Beta-Escin [11072-93-8]; Down 200; 3.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ADORA3,MTUS1,APAF1,CDK10,N4BP2L1,INA,LARGE1,IQCK,DZIP3,DGKG,DTNA,ING4,RASGRP2,ZNF589,KIAA1109,FGFR1,GALC,SEPT9,INPP5K,GRIK5,PADI2,DHX35,HSF2,KPNA5,MDM4,GIT1,MYT1,NEK1,NUMA1,OCRL,ODF2,PDE4B,CCSER2,PLP1,PPP5C,MAPK3,PTAFR,RAB3IL1,PLPPR3,CAND2,ZC4H2,NXT2,AHCYL2,RBFOX2,ZNF225" Drug 6158_DN Mephenytoin [50-12-4]; Down 200; 18.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,ARRB1,NCOA1,ATP6V0A1,CDC42,AKAP7,CRMP1,CRY2,CSNK1E,DZIP3,ZFYVE16,RIMS3,DAPK1,DAPK3,RABGAP1L,ABI2,PLXNC1,TNK2,TRAF3IP2,GALC,ALDH1L1,GLS,VWA5A,MOBP,PDE4B,CDK14,CCSER2,ZNF821,ZCCHC24,IZUMO4,EMC1,RAP1GAP2,SS18,SYN2,TEX15,CHST8,TGFBR3,TMOD1,KCTD2,ZMYND8,FLRT2,CLIP2,ZIC3,NT5M,KCNAB1" Drug 6426_UP 0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BIN1,CDC42BPA,APBB2,PPFIA3,MARCH3,ARHGEF7,CA12,CAMK2B,ARHGEF2,TPP1,CSF1,CSNK1E,VCAN,GPRASP1,MFAP3L,SMG7,EDIL3,IRAK4,DMTN,STX2,ETV1,FHL1,FYB1,FYN,SPACA9,ATXN2L,ELOVL5,KIF5C,MAPT,MBD1,MMP16,SLC11A2,NUMA1,POLG,WDR25,RAD52,ST6GAL1,TNIK,LHPP,CAMTA2,HIRA,UBE2H,MPPE1,ST7,KAT6A" Drug 307_DN sulindac; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "C1QTNF1,PKP4,APOC1,APP,NCOA1,CADM3,LRRFIP1,CHRM4,CLCN3,C2CD2L,ATN1,ABCC9,OPTN,MRNIP,RGS17,HSD17B14,LRRC23,FGFR1,RUNDC3A,NR3C1,AFF1,MMP16,NF1,NNAT,NTRK3,TNPO2,MTMR10,RAD51D,SUSD4,PBRM1,CLIP1,SH3BP2,RAB3GAP1,KBTBD4,EMC1,ZFR2,OBSL1,TNS1,CA14,UCHL1,PLPPR2,ZIC1,TFIP11,STMN4,EPM2A" Drug 7008_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "OSBPL1A,APBB2,APP,ARHGDIG,BRINP2,BCL2L2,BTRC,CFAP410,STOML1,QKI,SLC4A7,ENTPD4,ABCG1,FEZ1,FAM169A,DTNA,EDNRA,PLEKHO1,GLS,CNTRL,GRB10,CACFD1,NR3C1,MUM1,IL6R,SMAD1,MBD1,MEIS1,CNOT4,ELOVL2,ZSCAN32,PEX5,RAD51D,RALGDS,WLS,FBXO11,SLC20A2,SLC22A4,PHLDB1,ARHGEF9,SEMA4A,ZBTB14,DNALI1,UBE3B,DPF3" Drug 4022_UP Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABAT,ARSE,CACNG1,TPP1,AKAP6,CPS1,ENTPD4,EDRF1,RIMS3,BRINP1,HIPK3,EIF4G2,SRPK3,ETV1,OGA,SIGLEC8,NEU3,JAK2,KCNC1,KCNN1,NEUROD2,NF1,CNOT4,PALM,PCDH9,RETREG1,PLCD1,LRP12,PKN2,MAPK8,CNNM2,PTAFR,ELOVL2,BEND5,DOP1A,HECW1,SPTAN1,INKA2,FAM168A,TBL1X,CRTC1,SLC44A1,TMPO,CHST5,PHTF2" Drug 6500_DN (1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,ABHD6,APC,EPB41L5,APLP1,EIF4G3,CDH8,MAGI1,CRLF1,PLAA,COL9A2,DZIP3,DBT,JAKMIP2,TRAPPC9,DSCAM,EDNRA,F3,PDLIM5,SRCAP,COPS8,STON1,KCNH2,KIF5C,VWA5A,MIA2,NUCB1,PIK3CD,PTPN13,SH3BP2,MAPKBP1,SS18,NXT2,MAPK8IP3,MCF2L,SATB2,RPGRIP1L,PSD3,TPD52,SSBP2,FAM155A,VGF,CLDND1,XRCC4,ZFAND5" Drug 2893_DN Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "LTBP4,APOC1,ADAM15,BCL7A,BMP7,BTRC,ARHGEF1,ARHGEF2,QKI,NECTIN3,SOCS5,PDE4DIP,NOS1AP,MFAP3L,EXOG,DTNA,EFNA3,ZNF589,B4GALNT1,MSL3,GSN,TJAP1,KCNH2,NPR2,NLE1,PRPH,PLPPR1,PTHLH,ELOVL2,FAM184A,ROM1,SYBU,EPN2,TTBK2,STX1A,PDLIM2,TMOD1,TRPC1,UBE3A,PLPPR2,LMF1,SEMA3B,ST7,SMIM8,PHTF2" Drug 6816_DN Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABHD6,ARHGDIG,ATP6V0A1,CFLAR,ARHGEF7,BTRC,KRIT1,SYNGR3,LRRFIP1,TAOK2,NCOR1,ABCG1,CSNK1E,SOCS5,RIMS2,DCAF8,ZNF337,DTNA,EDNRA,FEM1B,PHF20L1,EPB41L1,STX2,EZH1,F8,ZNF589,MAN1B1,KCNH2,PDE3B,LRP12,PPP5C,ZCWPW1,RBBP6,RGS12,NEK11,RPS6KA2,SBF1,SH3BP2,ZHX3,ELOVL4,TCF7,VAV2,LMF1,TFIP11,EVI5" Drug 3415_UP Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASPHD1,MRTFA,DOC2A,APBB2,GAS7,CDK13,SLC4A4,KIF1A,ADAM15,NEURL1,TPP1,HOMER3,ATRNL1,PDE4DIP,MAML1,DAPK3,GIT2,EGR3,SORBS3,EN2,FHL1,PDLIM5,SEPT9,GFER,TDRKH,SPACA9,ITPKB,KCNH1,MDM4,MITF,PDE3B,PIK3CD,STRN3,RAB3IL1,RGS12,GSTCD,SLC1A7,SOX3,EXOC7,WSCD1,DOCK9,ARHGEF12,TK2,TMOD1,SMIM8" Drug 1574_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; HL60; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,MRTFA,ANK2,ARNTL,ARRB2,RIPK1,CLDN10,CHRNB2,PPP1R16B,ARHGAP32,C2CD2L,MED12,ANKRD46,SIDT2,EPB41L2,ECSIT,FGFR1,TRMO,MPP6,ALDH1L1,COPS8,DBF4,PADI2,ITGAM,KCNN1,MAP4,MBD1,AFF1,NEFH,NRGN,SLC25A23,LRP12,PTK2,MYH14,RPS6KA2,KBTBD4,KDM4C,SPART,EXOC7,TBL1X,VAV1,TFIP11,EVI5,ACTR3B,AAAS" Drug 1906_UP Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PPFIA3,PDXK,ATP2B1,SCAPER,CDC27,TAOK2,SOCS5,SPOCK2,ZBTB24,G3BP2,DTNA,EML1,ACSL4,OLFM1,SEC23B,STAG2,TRAF3IP2,CRCP,GLS,CACFD1,MAP4K5,KTN1,NPPA,PAK3,PPM1B,PPP3CB,MAPK10,GON4L,C1orf109,TMEM231,ARID4A,TRIM68,RGS12,NUDT11,FAM102A,SLC11A1,MAPKBP1,THSD1,TACC1,SEZ6L,UBE3A,XRCC4,ZNF189,MPPE1,AAAS" Drug 4316_UP Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ACHE,CDK10,BRINP2,RASL11B,BMPR1B,CACNA1I,CRLF1,ABCG2,DNAJB5,CSNK1E,IPCEF1,CYBB,SPOCK2,DTNA,EFNB3,ZMYND10,FOXF2,TBR1,GAD2,SYT17,GLYR1,GNAO1,GRM7,SOX21,KCNMA1,KIF5C,MOBP,NUCB1,NUMA1,PBX1,TNPO2,PEX5,RFX2,RGS4,ATP8B4,SELL,SH3BP2,PKNOX2,SLC9A5,KDM4B,ZSWIM8,CRTC1,DAAM2,TNS1,KCNAB1" Drug 3439_UP Merbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ABR,APBB2,APC,APLP1,APOC1,CDK13,ZBTB10,NEURL1,ZFYVE9,AKAP7,GREB1,DCAF8,JAKMIP2,RCAN1,KAT8,KIAA1109,FHL1,IQCG,GALC,NCKAP1,INPP5K,POLL,GPER1,MAN2A2,KITLG,PDE1C,PLEC,MINDY2,PTK2,RGS3,RGS10,SYBU,SMTN,FAM214B,BTBD7,SLC22A4,LIMCH1,EMC1,ST5,INKA2,PHLDB1,AGTPBP1,HEY2,TMPO,LAT2" Drug 7218_DN Avermectin B1 [71751-41-2]; Down 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "MTUS1,CDC42BPA,ATM,CFLAR,KRIT1,LHX2,NMT2,MAP4K4,LRIG1,SOCS5,PDE4DIP,CTH,PPP6R2,DBT,NR1D2,SUGP2,IRAK4,ATP2C1,CSPG5,GHR,ZNF276,TXNL4A,ICA1,IL6ST,MBD1,MMP16,NCAM2,PRKAR1B,GON4L,RIPOR1,NKAIN1,ROM1,RXRA,FAM192A,SUPT20H,ZNF430,MAPKBP1,ZSWIM8,CLASP2,STXBP1,JMJD6,VAMP1,TCF7,MPPE1,GAN" Drug 7414_DN Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,KIDINS220,CDK10,MPDZ,SYNJ2,SYNGR3,EPS15L1,IQCK,PDE4DIP,EDRF1,HP1BP3,LYPD1,DLG3,DSCAM,DTNA,CELF1,MPP6,SRCAP,GLYR1,MUM1,KCNJ3,CCSER2,PRKAR1B,PTPN13,TCP11L1,FOXRED2,FERMT1,FNDC3A,ABLIM3,PEX26,RAB3GAP1,FNBP1,ELOVL4,CEP68,TACC1,EXOC7,SIN3B,TCF7L2,HIRA,LMF1,NSD2,ZNF45,REEP1,GDPD5,SMIM8" Drug 2902_UP Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "TKTL1,ADRA1B,BIN1,CDC14B,PRX,CACNA1G,CHN1,CNTN1,C2CD2,DZIP3,DAPK1,SPOCK2,KLHL3,CDON,FAM13A,ETV1,FER,FGFR1,FLT1,GPR153,GAA,GFER,ZNF276,GRIK5,SYNPO,ITPKA,KCNMA1,MOBP,ADAM22,TNPO2,POU3F4,CEP41,RGS10,TCP11L1,SYNDIG1,SEC14L1,PKNOX2,ARHGAP26,CDK19,TACR1,TBCEL,PCDHGA1,ZKSCAN5,KCNAB1,TIGD6" Drug 7235_DN Trimeprazine tartrate [4330-99-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APBB2,CDK10,ARRB2,MTMR2,BTRC,CACNA1D,NFS1,SCARB1,QKI,ARHGEF6,MICAL2,DZIP3,DCAF8,DAPK3,DTNA,TOM1,EDNRA,FEM1B,SIDT2,EGFR,VPS26C,F3,DPYSL4,DISC1,MSL3,HNMT,DIPK1A,JAK2,KCNJ3,MPP2,OGDH,ROBO1,SBF1,ZFP30,EPN2,SLC20A2,MAPKBP1,KDM4B,ELOVL4,CEP68,KAZN,DNMBP,KLC2,SF1,NDRG4" Drug 7313_DN Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AP2A2,NME5,APOC1,CDK10,KYAT1,RCBTB2,CHN2,CLU,VCAN,PARD6A,DLG3,CDON,EML1,SPEG,VPS26C,F3,GPM6B,RASSF8,MAN1B1,MIA2,MN1,MX1,NUMA1,SERPINI1,RAB3IL1,SH3TC2,SUGCT,FBXW7,SAFB,MAPK12,ASAP3,FUZ,EPN2,FAM214B,ZNF415,TNIK,KDM4C,PHLDB1,FAM168A,ZNF34,R3HDM1,CABIN1,RUNDC3B,MICAL1,EVI5" Drug 1157_DN LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ADORA2A,APC,MARK4,CAPN3,CBFA2T2,SOCS6,TPP1,SH2B1,CSF1R,MICAL2,ZFYVE16,TRAPPC9,FRY,ERCC2,FECH,TRAF3IP2,LILRA2,CACFD1,ELOVL5,JAK2,MATK,NEFH,NF1,SETD4,GPR85,PLEC,PTPA,PRKCZ,TMEM104,ZSCAN32,GSTCD,CCDC25,SEC14L1,SMARCA4,WDTC1,SPATA7,ERC1,TSPYL2,PBLD,EXOC7,TCF7,TCF7L2,WBP2,UBTF,HPS4" Drug 7193_DN Streptozotocin [18883-66-4]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,BRAP,BIN1,CDC42BPA,CDK10,NCOA1,ATP6V0A1,SCAPER,ARHGEF1,FOXN3,CSNK1E,SDC3,SMG7,DTNA,TSPAN5,SIDT2,EIF4G2,SORBS3,CGREF1,FYN,GABRA2,SEPT9,HNMT,KCNF1,MATK,MBD1,MEIS1,OGG1,PRKAR1B,TMEM104,NKAIN1,RGS10,CCDC25,BTBD7,SPATA7,UNC5B,ZBTB43,ELOVL4,FAM168A,ASTN2,MCF2L,AHCYL2,RPRM,VGF,TIGD6" Drug 7517_DN vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BEGAIN,APLP1,ARHGAP5,ARNTL,MTMR2,KALRN,CAMK2G,ZFYVE9,FADS2,CREM,LRIG1,VCAN,RUSC2,EGFR,STX2,DLC1,GNG3,GPER1,CNTRL,BTN2A1,DHX35,LMO2,NFYA,PFKFB2,GON4L,FAM120C,RAB3A,RGS12,RNASEL,LGR4,CCDC88A,ARHGAP26,CEP68,TCF7L2,PSD3,TMEM121,DAAM2,SSBP2,VGF,CLDND1,XRCC4,LAMP5,EVI5,KCNAB1,SSPN" Drug 3642_DN Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,ADORA2A,AP2A2,AMT,ARHGEF7,LDLRAD4,CACNB2,RUNX1T1,SLC16A4,CD86,NEURL1,SEPT7,CHRNB2,ARHGEF6,RIMS3,BRINP1,EFNA3,EGFR,FGF13,FOXF2,GAD1,ALDH1L1,GPER1,PCLO,SMAD1,MAOB,MAP4,MMP17,ADAM22,MX1,PCBP3,PDE4A,TMOD2,RELN,RGS12,EMID1,SLC1A7,SPTAN1,SPTB,TBCEL,DOCK9,WNK1,KCNAB1,ITM2C,ADAMTSL3" Drug 376_DN raloxifene hydrochloride; Down 200; 0.1uM; ssMCF7; HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,NDRG2,ASCL1,DLGAP1,JAM2,IFFO1,AATK,CSF1R,DZIP3,GREB1,SRGAP3,E2F5,SIDT2,EGR3,ELN,FOLR2,NSG2,GAD2,AHDC1,GRIK5,GRIN1,BTN2A1,KCNJ5,KCNJ10,KHK,MN1,MX1,MYH7,NPTX1,OPCML,MBOAT7,MAPK4,SUSD4,GAL3ST4,RGS12,DCUN1D2,FOXRED2,ASIC4,ANKRD6,PEX26,SLC8A1,SLC9A5,ZSWIM8,EMC1,WIPF1" Drug 2976_UP Condelphine [7633-69-4]; Up 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PLA2G6,ANK3,KIF1A,CAPN3,NEURL1,GPR37L1,COL9A3,PDE4DIP,SMG7,ELAVL3,MRNIP,RASGRP2,KIAA1109,CSPG5,ALDH1L1,SRCAP,AHDC1,GRM7,PADI2,TJAP1,GIT1,NTRK2,PLCD1,MAPK7,RAB3IL1,TCP11L1,SCN2A,SH3BP2,SMTN,SNCA,SPTB,FCHO1,PLCB1,EXOC7,PDLIM2,WWC1,PCDHGA10,CRTC1,SLC35G2,TK2,TNS1,AMACR,VIPR2,XRCC4,GDPD5" Drug 7006_UP Etodolac [41340-25-4]; Up 200; 14uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,SLC12A5,ADRA1D,BTRC,CFAP410,NEURL1,BAG4,LRIG1,DCAF4,CTIF,HS3ST2,RCAN1,PLEKHO1,CDKL3,CORO2B,KAT8,DPYSL4,FYB1,GABRA1,DISC1,GRB10,NR3C1,KCNN1,KPNA5,IPO5,LIG4,LSS,MBD1,NF1,LRP12,MAPK8,PEX5,WLS,FOXRED2,CCDC88A,SHANK2,GLT8D1,POGZ,PLCB1,AHCYL2,TPD52,EMSY,KCNAB1,ST7,MARCH8" Drug 1303_UP Arecoline hydrobromide [300-08-3]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PLA2G6,CDC42BPA,CDK10,SEMA4G,LDLRAD4,CLCN3,NRG2,CREM,SIDT2,MRNIP,CDKL3,AFF2,EFCAB2,CGREF1,POLL,ATXN2L,MAP4,NEFH,NPTX2,NUCB1,OGG1,PMP22,MAPK3,TMEM104,PTAFR,PTCH1,RAB3IL1,RET,SEMA6D,PEX26,SLC11A1,SPART,KANK1,SYT5,ATP11A,MCF2L,PDLIM2,OBSL1,ATP13A2,KCTD2,CDK20,HIRA,VIPR2,NPDC1,PRDM2" Drug 5250_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,PLA2G6,APBA2,GAS7,BCAS1,APP,CDK10,SYNJ2,GYG2,SH2B1,NOS1AP,RASSF2,EXOG,SLC12A6,ING4,FGFR1,FHL1,NOP56,GAB1,NR3C1,PADI2,ELOVL5,AGFG1,ICA1,KCNF1,KCNH2,MPP2,NDUFA5,LRP12,PLPPR1,PTPRE,ATG16L1,ZDHHC14,ZFHX4,TCP11L1,RPS6KA2,SEC14L1,PPP1R9A,RBM34,TBCEL,TCF7,CDK20,KLC2,SMIM8,RNF146" Drug 6197_UP "ICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "MTUS1,SRPX,CNTNAP1,APC,KSR1,BTRC,CACNG1,CALB2,THSD7A,CACNA2D2,SLIT2,SIPA1L1,DZIP3,ATN1,TNK2,HSD17B14,VPS13B,OLFM1,TMEM8B,ALDH1L1,SPACA9,GRM1,GRM8,GUCY1A1,HSD17B1,KCNJ5,MDFI,CD200,NTRK2,OPRL1,SERPINI1,RETREG1,ZSCAN32,PTPN13,RGS12,RYR3,SH3BP2,EFHD1,KDM4B,CLSTN2,ZEB1,ICAM5,SEZ6L,VGF,EMSY" Drug 5786_DN Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "MARCH3,ALDH7A1,CHN2,SLC4A8,TENM4,CSF1R,SDC3,ARHGAP24,KIAA0513,GIT2,C2CD2L,DLG3,EDNRA,FAM13A,CDKL3,ZNF589,ZMYND11,C1QL1,GPR19,GUCY1B1,KIF5C,MAPT,GIT1,NF1,OGG1,MAPK7,TMEM104,PTPRN2,PEX5,BEND5,PAQR6,SH3BP2,ASAP3,TNIK,MCF2L,EXOC7,IQCE,WSCD1,KIAA0930,CLASP1,DNAH7,CHST8,GPR161,UGT8,KAT6A" Drug 1135_DN minocycline; Down 200; 10.5uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ADD3,BRAP,ARRB2,ADAM15,AP4M1,LRRFIP1,EPS15L1,PPP6R2,RUBCN,SGSM2,MED12,RCAN1,SH3GLB1,SORBS3,PLEKHO1,EPB41L1,VPS26C,SCML2,INPP5K,MALT1,GLS,GRB10,CACFD1,KIF3A,HPS5,KIF2A,MAPT,MYO5A,NRCAM,CCSER2,KCTD15,MAPK3,PBRM1,DCUN1D2,SAFB,SLC15A2,ARFGAP1,SP2,SS18,NSFL1C,TSC2,ZNF45,ZBTB38,JMJD1C,LAS1L" Drug 6908_UP BAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "SEMA6A,APOC1,MARK4,ATP2B1,MPDZ,SYNJ2,ARHGEF7,CAST,ZFYVE9,RNF14,ABCG1,SOCS5,PPP6R2,GIT2,ABI1,APH1A,F3,F8,NCKAP1,CNTRL,BTN2A1,HNMT,KCNJ3,CCSER2,C1orf109,ARID4A,SEC61A2,PCMTD2,ATXN1,PPM1E,SYBU,SLC15A2,LMBRD1,NEK4,TCF7L2,TCF12,DOCK9,TK2,BEX4,NPL,HIRA,CLDND1,XRCC4,MAP3K12,JMJD1C" Drug 4573_DN Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "C1QTNF1,PKP4,CDK10,CFLAR,BTRC,PLEKHB1,TPP1,ARMC8,CPS1,AATK,PDE4DIP,SNPH,EXOG,EDNRA,EN2,ETV1,ST3GAL6,OGA,GAD1,MAP4K5,MITF,MT1M,ZNF862,CNOT4,OPCML,PFKFB2,GRAMD1C,PROX1,CNNM2,PID1,RAD52,RXRA,ZNF821,ZNF415,ELOVL4,SYT1,ATP11A,KIAA1107,WSCD1,TRPC1,FAM155A,VIPR2,PCBP4,FZD3,SMIM8" Drug 2381_DN Flunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,ALK,ARNTL,MARK4,NCOA1,CFLAR,LDLRAD4,CAMK2G,SLC25A14,CD86,SOCS6,NIPBL,CSF1R,SPATA2,SORBS3,TNK2,F5,FGFR1,FHL1,USP19,RAB40B,LILRA2,LIG4,GIT1,NF1,PIK3R1,SNRK,TMEM231,MAP6D1,PAQR6,PPP4R3A,DOP1A,ZBTB43,POGZ,STXBP1,TCF7L2,ARHGEF12,HIF3A,SLC44A1,TK2,KAT6B,RBFOX2,UBTF,WIPF1,MARCH8" Drug 4694_DN Mebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APC,MARK4,MPDZ,BCL2L2,MTMR2,BTRC,NIPBL,ARMC8,PDE4DIP,DNAJC6,LYPD1,RABGAP1L,RBM12,PLEKHO1,FGFR1,FGFR3,DPYSL4,GAD1,ZMYND11,GHR,GLS,PSIP1,BRINP3,MMP16,MTR,LYRM9,NFYA,ODF2,PCDH9,PIK3R1,RETREG1,LRP12,PKIA,FAM184A,ARID4A,MSANTD2,FBXO11,USP33,ZHX3,SPART,CLASP2,TACC1,IQCE,HIRA,FAM155A" Drug 371_UP rofecoxib; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "SLC4A4,ATP2B2,CFLAR,CA12,CD38,LARGE1,PCYT1B,NCAN,RIMS2,SMG7,SIDT2,TNK2,F8,TESK2,ZNF589,FGFR1,GPR153,SEPT9,GRIA4,AP4S1,KCNC1,KCND3,KCNJ9,VWA5A,MYT1,NTRK3,DDR2,OMG,CLDN11,CAMKV,MAPK8,PTH1R,C1orf54,RNASEL,SH3BP2,FNDC3A,FCHO1,STX1A,PLCB1,MCF2L,PCDHGA1,ZMAT3,CADM1,VGF,VIPR2" Drug 1802_DN Panthenol (D) [81-13-0]; Down 200; 19.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "C1QTNF1,APBB1,APOC1,MARK4,PLEKHB1,EPS15L1,ARHGEF6,WHRN,SLC4A7,DAPK3,CNIH3,RUSC2,EIF5,EPB41L1,FGFR1,BAIAP2,SYT17,DISC1,FERMT2,GPER1,MX1,SETD4,OGG1,MBOAT7,TMEM104,ELOVL2,SEC61A2,MCMBP,MAPK12,ASAP3,FUZ,LIMS2,SIRT2,IFT122,FNBP1,MAPK8IP3,STX1A,IQCE,TCF7L2,ARHGEF12,TGFBR3,FAM155A,EIF4ENIF1,HPS4,SMIM8" Drug 7243_UP Urosiol [128-13-2]; Up 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,MTUS1,NME5,MRTFA,SEMA4G,ARRB2,KIF1A,CHN2,TAOK2,NRG2,SLITRK5,DAPK3,EGFR,DMTN,RABEPK,ATP8A1,FCGRT,TESK2,FOXG1,TRMO,POLL,PADI2,SHISAL1,MEF2C,SCAMP5,NF1,OCRL,MBOAT7,MAPK3,MAPK7,RGS4,PAQR6,SAFB,SBF1,SH3GL2,SLC1A3,FAM214B,ZNF667,SMARCD3,PSD3,CABIN1,SSBP2,WIPF1,NT5M,SMIM8" Drug 6838_DN Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "RALGAPA1,SLC12A5,BCAS1,ALDH4A1,ATM,ATP6V0A1,CFLAR,CAMK2G,KYAT1,PLEKHB1,CSNK1E,CTH,C2CD2L,PHF20L1,DENND4A,FGFR1,FHL1,OGA,GART,ZNF276,GPR19,CNTRL,IL6ST,MIA2,NUMA1,PDE3B,RETREG1,PRPH,APTX,PEX5,RGS12,EMC1,ERC1,TTBK2,DIP2A,AP4E1,BEX4,TRIO,ZMYND8,PLPPR2,ZNF45,HPS4,MPPE1,PHTF2,JMJD1C" Drug 7275_DN Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BRAP,PKP4,PPFIA3,BCL2L2,CLTB,CSNK1E,KIAA0753,TMCC2,DLG3,SUGP2,ING4,STX2,FHL1,ATP2C1,DISC1,WASF3,TXNL4A,KLF12,MEIS1,MYO6,ZNF862,NFIX,NFYA,PDE1C,PIK3R1,POLG,PRKAB2,BCAS3,RAP1GAP,ZDHHC14,PEX26,SMARCC2,CDK5RAP2,WDTC1,SP2,EXOC7,WSCD1,ARHGEF12,TJP1,HIRA,NSD2,PLSCR4,UBE3B,SMIM8,NUP214" Drug 6267_UP Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PLA2G6,APP,RGS20,ASPH,ST3GAL5,SYNJ2,CBFA2T2,CDH2,CHRNB2,VAX2,QKI,GREB1,GIT2,MFAP3L,KBTBD11,RCAN1,SUGP2,MBNL2,F5,KAT8,C1orf61,GLYR1,ATF7,GRIK5,KCNJ3,KITLG,PDE3B,CCSER2,MAPK8,BSDC1,ZMAT4,GSTCD,ROBO1,ZNF821,SMTN,CLSTN2,STXBP1,IQCE,ZNF34,ZMYND8,LMF1,MAP3K12,GDPD5,UBE3B,GAN" Drug 2943_DN Asiaticoside [16830-15-2]; Down 200; 4.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "BIN1,CDK13,NUMB,SLC4A4,ADAM23,FOXN3,PLAA,COL9A2,CSF1,SMG7,DLG4,EXOG,ECSIT,CACFD1,MUM1,KIF2A,MAP4,MX1,ZNF862,NRGN,NUCB1,OLR1,GPR85,PFKFB4,PIK3CD,SLC25A23,PILRA,PTPA,MAPK8,PTAFR,ARHGEF10L,TCP11L1,MAP6D1,ZNF821,SH3BP2,ANKRD6,MAPKBP1,SUPT5H,ZEB1,TPM3,ZKSCAN5,UBTF,WNK1,NT5M,GDPD5" Drug 1272_UP Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG3,MTUS1,APAF1,APBB2,NCOA1,CFAP410,CAPN3,CLGN,CLCN4,SLC4A7,CHD1L,SIPA1L1,ARHGAP32,ZFYVE16,RCAN1,VPS26C,CELF1,GNAO1,GPD2,TJAP1,LSS,SLC11A2,SLC25A23,RC3H2,PPP3CC,PTAFR,PTPRO,PPM1E,DZIP1,ELMO2,ZKSCAN3,PALLD,TMCC1,FNBP1,TROVE2,LARP4,MLC1,ATP11A,DNMBP,ZEB1,CHST8,TPD52,FLRT2,VAV2,SENP7" Drug 7500_DN "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ADD2,BIN1,AMT,STX16,ATP6V0A1,ADAM15,CFLAR,ST3GAL5,KALRN,ADGRG1,FOXN3,CHD1L,DAPK3,DBT,MBNL2,SORBS3,FLNC,ANKFY1,TRMO,BTN2A1,MAP4K5,HSF2,IL6R,INPP1,KCNK1,OPRL1,PDE3B,GSTCD,PKNOX2,CCDC88A,SLC20A2,UHRF1BP1L,THSD1,SS18,INKA2,MAPK8IP3,VPS13A,TCF7L2,AHCYL2,TMPO,TPD52,VIPR2,TFIP11,KAT6A,FXR1" Drug 3270_UP Myricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ACTN2,ARID1A,ADORA1,AP2A2,BIN1,PPP4R4,MARK4,ASPH,NUMB,SLC2A11,ATP6V0A1,BCL7A,BMP7,NEURL1,ARHGAP33,CLTB,AKAP7,RUSC2,DTNA,RRAGB,FGF12,FHL1,PDLIM5,GRIK5,HSD17B1,KITLG,ADAM22,MYO9A,ZNF862,NUMA1,CNNM2,PTAFR,RAP1GAP,ZNF821,PEX26,DHX30,FAM214B,TROVE2,NCDN,ROBO3,SYNE1,TMOD1,WBP2,SPHK2,EMSY" Drug 1327_UP Piperine [94-62-2]; Up 200; 14uM; HL60; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "MTUS1,OSBPL1A,GAS7,BCAS1,ARRB1,ATP6V0A1,MYRF,SCARB1,HOMER3,MICAL2,CSNK1E,VCAN,CYBB,DOCK4,KIAA0586,DLG4,NR1D2,RASGRP2,PTK2B,CAMKK2,DISC1,SEPT9,GLYR1,MAN1B1,IRF8,NF1,SLC11A2,P2RX7,PDE4B,SNRK,ZCWPW1,RNH1,DGLUCY,SH3BP2,SMARCA4,SMARCC2,SPTAN1,ZBTB43,STX1A,TCF4,SZT2,THBS4,ZMYND8,PLPPR2,LAMP5" Drug 7430_UP Niflumic acid [4394-00-7]; Up 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASPHD1,ALDH4A1,KSR1,ST3GAL5,SCAPER,CFAP410,CHM,PLEKHB1,NECTIN3,FEZ1,TBC1D5,ARMCX2,JAKMIP2,C2CD2L,NR1D2,ABI2,VPS13B,COQ7,VPS26C,TESK2,FHL1,FOXG1,INPP5K,ICA1,KCNF1,KCNN1,ADAM22,PDE3B,SERPINE2,RETREG1,ING3,FSD1,PTCH1,RAB3IL1,RGS12,GSTCD,SEC14L1,FAM214B,SNCA,RAP1GAP2,SS18,LMF1,NDRG4,MAP3K12,UBE3B" Drug 2623_DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "APAF1,APBB2,CFLAR,MAP7,KYAT1,ZFYVE9,NIPBL,SLC4A8,ABCG1,DBT,DCTN1,LYPD1,SGSM2,G3BP2,EFNA3,FHL1,AGAP2,MSL3,GPD2,GPER1,NUDT21,KHK,LIG4,PLEC,PRKACB,PEX5,RAD51D,ZCWPW1,ZDHHC14,CCDC25,RPS6KA2,SBF1,ZNF821,SGK1,ABLIM3,SLC20A2,PDZRN3,ASTN2,TACC1,TK2,PLPPR2,LMF1,XRCC4,ZNF23,MPPE1" Drug 1571_DN Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; HL60; HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AK2,AMT,ATM,CFLAR,CA12,HIP1R,PLAA,SLC4A7,ZEB2,RCAN1,DCTN4,VPS26C,CAP2,UFM1,FAM49B,CELF1,OGA,GSN,NCKAP1L,NOS1,PDPK1,ZNF426,LRP12,PPP3CB,TTC13,RPRD1A,CLIP1,ATXN7,SLC2A5,ZNF430,ARHGEF40,SLC11A1,SLC15A2,SLN,SNAP25,POGZ,COLGALT2,DIP2A,KANK1,NSFL1C,TBL1X,NSD1,TMPO,EIF4ENIF1,PHTF2" Drug 7443_DN Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PKP4,PPFIA3,APP,ASPH,MTMR9,MPDZ,SYNJ2,TAOK2,STOML1,CSNK1E,SIPA1L1,PDE4DIP,GPRASP1,ZNF337,TBC1D5,TRAPPC9,EDNRA,TNK2,KAT8,FGFR1,EFCAB2,CGREF1,B4GALNT1,CNTRL,MAP4,MPP2,PPP2R2B,LRRC49,ZCWPW1,ABLIM3,ZKSCAN3,KDM4B,FNBP1,ELOVL4,STXBP1,ASTN2,ATP11A,KAT6B,TPM1,TRPC1,UBTF,PLPPR2,VIPR2,ZNF23,ST7" Drug 5500_UP Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,ADORA1,ADRA1D,MRTFA,TRMT9B,CACNB4,HAP1,CDO1,WHRN,CSF1R,ATRNL1,VCAN,BRINP1,SPOCK3,DRD1,EFNA3,ING4,TNK2,LRRC23,APC2,CORO2B,FGFR1,FOXG1,GABRA2,HBS1L,GNAO1,GPM6B,CNTRL,NR3C1,SYNPO,TJAP1,IGSF1,ADAM22,NRGN,NUCB1,CAMKV,RGS7,RPS6KA2,KCNIP1,SLC2A5,SNCA,COLGALT2,RPGRIP1L,TMEM151B,FLRT2" Drug 3479_UP Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,AMT,KCNAB2,ARHGDIG,RCBTB2,DNAJB5,GREB1,SNPH,MAML1,GNE,PLEKHA1,DENND4A,VPS26C,RRAGB,ZNF589,SORBS1,MSL3,DIDO1,MAP4,ZNF862,NNAT,NPR2,PCDH9,MTRF1L,GRAMD1C,PRPH,PSMD13,GTDC1,RGS4,RGS12,TCP11L1,ASAP3,PREX2,BTBD7,ZHX3,KDM4C,MAPK8IP3,DIP2A,PLCB1,KIAA0930,PCDHA6,ZNF106,SLC44A1,FLRT2,ITM2C" Drug 5621_DN Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,KIDINS220,LTBP4,AMT,PDE8B,MTMR3,CAMK2G,ARHGEF2,CRLF1,TAOK2,SLIT2,FADS2,SULT4A1,EDRF1,DAPK3,SGSM2,EFNB3,SORBS3,IL6R,MAP4,MATK,EPN1,MINDY2,MAPK8,TMEM104,ELOVL2,FAM120C,ZCWPW1,RGS12,KCTD17,SBF1,WDTC1,DOK5,EMC1,IQSEC2,PLCB1,MCF2L,CRTC1,CHST8,ZNF34,TK2,CABIN1,KCNK12,ZNF711,SSPN" Drug 1510_DN Erythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARRB1,CFLAR,BTRC,SPAG9,CBFA2T2,PLEKHB1,SULT4A1,AKAP7,SH2B1,CRY2,FEZ1,DZIP3,DCAF8,AHDC1,GLYR1,GLS,GPD2,GRB10,BTN2A1,ADAM22,LYRM9,PDE3B,RETREG1,PPP3CC,TMEM104,NEK11,TCP11L1,SLC15A2,SMARCD3,ZHX3,UNC5B,ZBTB43,CEP68,ANKRD12,TBL1X,SIN3B,TNS2,CRTC1,AHCYL2,RBFOX2,ZMYND8,VGF,KLC2,EPM2A,GAN" Drug 2214_UP Diazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "AP2A2,MRTFA,APAF1,CACNA1I,CHM,CHN2,QKI,MAML1,SPOCK2,MBNL2,STX2,DLC1,C1orf61,SORBS1,TPK1,RND1,IRF8,KCNH2,KCNJ5,KIF5A,MBD1,AFDN,TAGLN3,ZNF862,NOVA2,PCBP3,NTRK2,KHDRBS2,RPS6KA2,RYR1,SH3BP2,PPP1R9A,ASAP3,LIMS2,SLC9A5,SNAP25,ZCCHC24,NPAS3,ATP11A,SMG6,PSD3,CRTC1,PCDHA5,TNS1,SLC17A7" Drug 3405_UP Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ARID1A,SLC12A5,PLA2G6,MRTFA,APBA2,ATP6V0A1,MTMR3,CACNA1I,LDLRAD4,CALB2,CAMK2G,CDC42,COL9A3,DCAF8,DAPK3,DMPK,RCAN1,EFNB3,ANKMY1,CAMSAP1,POLL,GPM6B,GPER1,SPACA9,ICA1,IRF8,IL11RA,KCNH2,GIT1,PTAFR,RAD52,KCTD17,KIF16B,ZNF365,FAM214B,ZCCHC24,SPTAN1,IQCE,PCDHA6,THRA,TRIO,VGF,MICAL1,REEP1,SLC17A7" Drug 3053_DN Caffeic acid [3331-39-5]; Down 200; 22.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,PLA2G6,MRTFA,ATP2A2,KSR1,LDLRAD4,HIP1R,SLC16A4,TPP1,HOMER3,DYRK1A,CELSR3,EGR3,SORBS3,MTSS1L,KIAA1109,GABRA2,AHDC1,GPM6B,LILRA2,SPACA9,GRM1,GRM7,ATXN2L,ELOVL5,TJAP1,SMAD1,MID1,AFF1,AFDN,MPP2,NNAT,NOS1,PDPK1,LRRN3,PTAFR,ZNF493,RGS3,SS18,NSD1,TNS2,TNS1,TRPS1,FLRT2,KCNAB1" Drug 7390_UP PNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Up 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "CDC42BPA,KCNAB2,APBB2,ATP1A3,SLC4A4,CDH10,PDE4DIP,SDC3,CTNND2,RUSC2,CHRDL1,DPH1,ATN1,EIF4G2,MTSS1L,ETV1,RRAGB,TAOK3,FGF1,OLFM1,FGFR1,OGA,DENND2A,LPAR4,DIPK1A,NTRK3,CLDN11,PPARA,FAM184A,ARHGEF10L,FBXW7,RXRA,TRAPPC13,ASAP3,DOCK9,RALYL,TMEM121,AMACR,ZKSCAN5,VIPR2,XRCC4,REEP1,EVI5,UBE3B,NUP214" Drug 4794_DN Diflunisal [22494-42-4]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "CDC42BPA,CDC14B,CFLAR,GYG2,CFAP410,CACNB2,HAP1,LRRFIP1,PPP6R2,NOS1AP,GPRASP1,MFAP3L,ATN1,RCAN1,ANKMY1,FECH,FGFR1,CAMSAP1,C1orf61,DPYSL4,GLS,SPACA9,ELOVL5,MAP2,MID1,AFDN,NOS1,SLC11A2,PPARA,RAB3IL1,RPS6KA2,SH3BP2,ANKRD6,KIF13A,IQSEC2,WDR7,PCDHGA10,DOCK9,NSD1,THRA,PARD3,VLDLR,LMF1,XRCC4,KCNAB1" Drug 3033_DN Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "PKP4,APAF1,KIF1A,AZGP1,LDLRAD4,CAPN3,KYAT1,QKI,CPS1,DBT,RUSC2,SMG7,EXOG,HIPK3,SIDT2,COQ7,FCGRT,ZNF589,CAMKK2,KHDRBS3,GABRA2,INPP5K,LILRA2,SPACA9,ITGAM,NFYA,CNOT4,ENPP2,PKN2,PTAFR,RALGDS,ZNF671,PPM1E,KDM4C,SS18,FBXW11,TBL1X,TCF4,DMXL2,TCF7L2,FLRT2,LMF1,LAT2,ZNF189,PHTF2" Drug 5262_DN Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "NDRG2,AP2A2,PLA2G6,ALK,APC,SEMA4G,ALDH7A1,SYNJ2,CFAP410,CA4,CACNA1D,HOMER3,ARHGEF4,RASSF2,MFAP3L,PARD6A,GNE,CNNM1,EFNA3,MRNIP,PIPOX,FGFR1,CACFD1,KIF5A,NPTX1,GPR85,PENK,PLEC,MBOAT7,ZFHX4,NEK11,FBXO11,EPN2,SLC9A5,CXXC4,COA1,WDTC1,ZCCHC24,KAZN,PDLIM2,WSCD1,TCF7,TRIM2,SIK3,ZIC3" Drug 121_DN "estradiol, USP; Down 200; 0.01uM; MCF7; HG-U133A" Broad Institute CMAP Down 5.96E-03 1.00E+00 3.06E-02 3.48E-01 45 198 "ASIC1,CNTNAP1,APBB2,GAS7,PPFIA3,CDK13,RAB29,LRBA,CHGB,AATK,RIMS3,ATN1,RCAN1,BAIAP2,NCKAP1,CACFD1,MAN1B1,KIF5A,AFF1,NAP1L1,CNOT4,NUMA1,CCSER2,PLCD1,PLEC,PLXNB1,PPP3CB,PRPH,PTK2,RIPOR1,RPS6KA2,ITSN1,SLC2A5,LIMS2,SHANK2,WDTC1,TSNAXIP1,TSPYL2,ST5,STX1A,CBX5,METTL3,ZMYND8,UBE3A,PRDM2" Drug CID000004122 nocodazole Stitch 5.96E-03 1.00E+00 3.06E-02 3.48E-01 96 478 "OGT,MYH7B,APC,CDK13,PROM1,CALM1,MAP7,KRIT1,ARHGEF2,CDC27,CDC42,TAOK2,EPS15L1,COG1,CLTC,CNTN1,MYRIP,NSL1,SEC31B,AKAP12,PPP1R16B,CALY,APPL1,CTNND1,DCTN1,PARD6A,TUBD1,GPHN,APC2,PTK2B,TUBB3,TUBB4A,ACTL6B,SYNCRIP,DCTN2,SMC2,RASL10A,TUBA8,GGT7,HPGDS,GOLGB1,EML4,TUBA1C,HSP90AA1,TUBB2B,STMN1,MAP2,MAP4,MAP6,MAPT,BLOC1S2,MYH3,MYH6,MYH7,MYO5A,MYO6,MYT1,NUMA1,CDK14,FSD1,PPP2R2C,PTPA,PPP2R5E,PPP5C,PRKCZ,MAPK3,MAPK8,PTK2,PTPRN2,PTPRO,STRC,PPP2R3C,RBBP6,MYH14,PCMTD2,MAP6D1,CLIP1,MYO18A,FNDC3A,SEC31A,SPTB,EXOC7,TBL1X,TF,CBX5,ACTR6,TSC2,TUBB2A,TUBB1,UBC,GORASP1,OSBP2,VAV2,MICAL1,ANKS1B,TUBA1A" Drug ctd:C551994 crizotinib CTD 5.97E-03 1.00E+00 3.06E-02 3.48E-01 16 53 "ALK,PROM1,FADS2,ABCG2,EGFR,F3,FGFR1,EML4,HMGCR,KCNH2,KIT,MYCN,NTRK2,ABCB1,MAPK3,TEK" Drug 4827_DN Emetine dihydrochloride [316-42-7]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 5.97E-03 1.00E+00 3.06E-02 3.48E-01 41 177 "ACLY,ASPH,MTMR2,CA12,MICAL2,SOCS5,ARHGAP32,RIMS3,SACS,E2F5,EGR3,PLEKHO1,CAMSAP1,RAB40B,GPD2,LAMP2,MAPT,NRCAM,OPA1,SSH1,ZFYVE21,PMP22,SYTL2,PTK2,PCMTD2,CDK19,FAM168A,SYPL1,PSD3,ZMAT3,CBX5,TMPO,RBFOX2,TPD52,SMUG1,REEP1,SLC38A1,FZD3,MARCH8,NETO2,GAN" Drug 1017_UP fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.11E-03 1.00E+00 3.13E-02 3.56E-01 40 172 "LRRFIP1,SULT4A1,LRIG1,PDE4DIP,MAML1,DSCAM,DTNA,OPTN,EFNB3,FGF13,CAMSAP1,HBS1L,ALDH1L1,SLC2A6,HMGCR,ICA1,INPP1,LSS,ADAM22,NF1,CNNM2,PTCH1,ATG16L1,TCP11L1,RPS6KA2,ATXN1,SH3BP2,SYBU,RBM34,KDM4B,EMC1,CDK19,TSPYL2,MAPK8IP3,POPDC3,DMXL2,TRIM2,TK2,DNAJC12,EPM2A" Drug 2195_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.11E-03 1.00E+00 3.13E-02 3.56E-01 40 172 "AK2,KCNAB2,N4BP2L1,CAMK2G,SLITRK5,CX3CR1,KBTBD11,DPYSL2,FAM13A,ENO2,SH3YL1,ZNF589,PCYOX1,SEMA4D,CAMKK2,RAB40B,LILRA2,IRF8,ITGAM,ITPKB,LSS,PIK3CD,SNX10,KCTD15,RETREG2,PTAFR,PTCH1,DGLUCY,DZIP1,SLA,KIF21B,CEP68,GSE1,KIAA0930,TNS1,RBFOX2,TRPM2,LAT2,LRP8,ZNF248" Drug 1072_DN "Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 6.11E-03 1.00E+00 3.13E-02 3.56E-01 40 172 "ARID1A,BCAR3,CDK13,CFLAR,NIPBL,RCHY1,GREB1,DYRK1A,RASGRP1,EGR3,AMOTL2,SYNCRIP,TACC2,TRAF3IP2,ZMYND11,CRCP,SPIN1,DIDO1,BRINP3,JAK2,SMAD1,MAN2A2,RXRA,SCAF8,PPP4R3A,SON,ERBIN,ZC3H4,PUM2,DICER1,NACC2,TMPO,KAT6B,METTL3,TRPS1,UBE3A,ZIC1,ZNF142,LRP8,PRDM10" Drug 4969_DN Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "AP2A2,AK2,ANK3,CFLAR,MTMR2,CFAP410,CACNA1D,RCBTB2,AKAP7,PDE4DIP,CNTNAP2,ARHGEF4,ARMCX2,DLG3,DTNA,CNNM1,CELSR3,FAM49B,SYT17,GRB10,GRIK5,ATXN2L,KHK,VWA5A,MSI1,ZNF862,PBX1,PLCD1,PRKAR1B,RGS10,PPP1R9A,PPP4R3A,SMTN,KDM4C,DIP2A,SEMA4A,MCF2L,PSD3,ATP13A2,PARD3,KAT6B,CABIN1,EVI5,GDPD5" Drug 3412_DN Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ARID1A,ADD1,EPB41L5,EIF4G3,BCL7A,CFLAR,GYG2,CLCN3,INTS1,SMG7,DLG3,POLR1B,SEMA4D,ANKFY1,INPP5K,PRRC2B,GRB10,IGSF1,MAP4,MATK,MMP16,KCTD15,MBOAT7,PRPH,SIDT1,NKAIN1,FBXW7,EPN2,IFT122,WDTC1,ZHX3,KDM4C,CDK19,TSPYL2,FCHO1,NCDN,VPS13A,ATP13A2,TIAM1,KCTD2,TSC2,HIRA,PRDM2,HPS4" Drug 5074_DN Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "CDC42BPA,ALDH4A1,SLC4A4,BACH1,CA12,CBFA2T2,SEPT7,CDC42,DZIP3,ARHGAP24,EFNA3,EIF5,ERCC2,SPEG,ETV1,ZNF589,FOXG1,GLS,GPER1,KLF12,SCIN,INPP5B,MAP4,MX1,NASP,CLDN11,PPARA,SAMD9,RAB3A,RAD51D,ARHGEF10L,CSRNP3,SCN8A,ZFP30,DZIP1,SMARCD3,TNIK,KDM4C,CRTC1,TNS1,VIPR2,TRIM9,SPHK2,DPF3" Drug 3378_DN Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ALCAM,AMPD3,CDC42BPA,APC,FAM131A,APOC1,HAP1,CAMK2B,STOML1,WHRN,SLC4A7,NOS1AP,DNAJC6,DMPK,HIPK3,CAMSAP1,OGA,SRCAP,GPD2,INPP5B,JAK2,KCNH2,KIF2A,KIT,MAP4,MITF,ADAM22,NF1,ODF2,LRP12,FAM184A,ZFHX4,ZCCHC24,EMC1,IQSEC2,AJAP1,PLCB1,MTCL1,TBCEL,TCF7L2,TMOD1,VIPR2,KCNK12,ZNF24" Drug 4240_DN Letrozole [112809-51-5]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "MRTFA,ALDH4A1,ATP1A3,ADGRB2,BAIAP3,ARHGEF2,NRXN3,DNAJB5,SMG7,AK5,ATN1,SIDT2,SORBS3,MTSS1L,EZH1,AFF2,ZNF44,SEPT9,GNAL,HNMT,SCIN,LSS,MAPT,AFF1,ADAM22,ODF2,OPCML,PALM,PRKAR1B,MAPK7,ZSCAN32,PTPRB,FAM120C,RGS4,KIRREL1,FRMPD1,PPP4R3A,KANSL3,THRA,TIAM1,TPM2,SPHK2,WNK1,KCNAB1" Drug 6956_DN LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ABHD6,AK2,PPFIA3,KIF1A,MPDZ,SLC25A14,SYNGR3,HOMER3,SMARCAL1,PPP6R2,DAPK3,MFAP3L,FBXL5,EXOG,SIDT2,MRNIP,FGFR3,FHL1,EFCAB2,FAM49B,GPR153,MALT1,GRM8,RNFT2,ATXN2L,NF1,OGG1,OPA1,PCDH9,FA2H,TMEM104,RIPOR1,FERMT1,PPP4R3A,EPN2,EMC1,SEPT8,JMJD6,TPD52,LMF1,WRN,NDRG4,REEP1,C12orf4" Drug 4241_DN Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ADRA1D,APBB2,APOC1,PDE8B,KIF1A,ADGRB2,CFLAR,HOMER3,SDC3,TRAPPC9,CDON,ATN1,MBNL2,AASS,SORBS3,LRRC23,MTSS1L,TUBB4A,ST3GAL6,FYN,GABRA2,RUNDC3A,GRM1,MAPT,CNOT4,ODF2,PBX1,PDE4B,PLXNB1,PRKAR1B,WDR25,PTPRB,PAQR6,FRMPD1,LIMS2,KANSL3,EXOC7,TNS2,TEX15,SLC44A1,FAM155A,OSBP2,LMF1,TIGD6" Drug 881_UP "cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Up 200; 100uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "KIF1A,LDLRAD4,ARHGEF2,LHX2,TPP1,VAX2,BRINP1,MFAP3L,TSPAN5,AASS,ERCC2,ST3GAL6,FER,NOP56,OGA,ERAP1,GLS,GRM8,HNMT,INPP5B,KCNMA1,MBD1,MSI1,NF1,PIK3CD,LRRC49,FAM120C,RAB3IL1,KHDRBS2,SUGCT,FRMPD1,NLGN1,LIMCH1,SOX2,INKA2,MAPK8IP3,SEMA4A,SIK3,TIAM1,TRIO,VAV2,LMF1,DNALI1,SSPN" Drug 2540_DN Podophyllotoxin [518-28-5]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ADRA1D,ARRB1,ADAM15,C5,CAPN3,SCARB1,SPOCK3,NR1D2,CDON,EFNA3,SORBS3,MRNIP,LRRC23,RASGRP2,RAB40B,GRM1,SLC2A6,VSIG4,IDH3A,MYT1,NEFH,NNAT,SLC11A2,TMEM231,RAB3A,KHDRBS2,RET,ARHGEF10L,PLPPR3,FOXRED2,HSPA4L,FRMPD1,DZIP1,DDN,ZC4H2,NCDN,KANK1,KAZN,CDK20,TRIO,CFAP298,NT5M,NAV3,FAM13C" Drug 2872_UP Bromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ARID1A,PRX,LDLRAD4,CACNG1,THSD7A,HAP1,CDH10,ZFYVE9,FADS2,DNAJB5,COL9A3,GREB1,RIMS3,SPOCK2,MYEF2,RUSC2,CDON,C3orf18,ERCC2,FOXG1,NEU3,SRCAP,GNAO1,KLF12,HLF,ICA1,SHISAL1,MEF2C,AFDN,NF1,CEP41,MASP1,PTAFR,ZNF493,SLC1A7,PKNOX2,SLC9A5,IQSEC2,SPART,WSCD1,CHST5,TRIO,VLDLR,KCNAB1" Drug 3382_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "NME5,MRTFA,BIN1,CDC42BPA,FAM131A,ATM,CFLAR,SCAPER,BAIAP3,BTRC,NMT2,MFAP3L,EFNB3,STX2,SPEG,C1orf61,PDLIM5,GPR153,POLL,HNMT,INPP5B,KCNH2,KIT,MMP16,NPR2,SERPINE2,PLCD1,STRN3,MINDY2,RAB3IL1,SLC1A7,PPP4R3A,PKNOX2,BTBD7,RBM34,ZBTB43,PHLDB1,TBCEL,ARHGEF12,TK2,RPRM,WIPF1,KCNK12,MPPE1" Drug 1115_UP phenanthridinone; Up 200; 51.2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "OGT,ATM,STX16,KIF1A,BMP7,SYNJ2,MTMR3,CTNND2,PUM1,MED24,DLG3,MED12,DTNA,CELSR3,EGR3,PCOLCE2,ENO2,GPHN,TESK2,ATP2C1,SEPT9,SESN1,CIT,KIF3A,RNFT2,KCNJ3,VPS13C,ELOVL2,ARHGEF10L,DCUN1D2,PAQR6,SBF1,SH3BGR,URGCP,SMARCC2,EMC1,ZBTB43,CEP68,DIP2A,KAZN,KCTD2,TRIO,LMF1,UBE3B" Drug 3348_UP Azacytidine-5 [320-67-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ARID1A,ADD2,CDC42BPA,DDX3Y,CACNG1,CCKBR,SLC4A7,CREB5,DCT,ELMO1,RUSC2,NTM,ST8SIA3,ERCC2,PIPOX,AMOTL2,FLNC,CAMKK2,DLL3,GRIK5,NR3C1,GRM1,IL6ST,KCNB1,KCNJ10,MAP4,MYT1,NEUROD1,TREM2,ENPP2,CAMKV,PLTP,SAMD9,ZMAT4,SFPQ,PKNOX2,HECW1,CLSTN2,THSD1,SYT11,SPX,DNALI1,SEMA3B,TIGD6" Drug 5756_UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "DOC2A,AMT,APBB1,DDO,BCAS1,ARHGDIG,ALDH4A1,RAB26,WHRN,CRMP1,ABCG1,NOS1AP,ARHGAP24,RIMS3,GIT2,SRGAP3,EDIL3,ST8SIA3,EFNA3,DCTN2,SORBS1,GABRA2,DENND2A,LYVE1,ELOVL5,IL6ST,MAN2A2,TAGLN3,NF1,NPTX1,NUMA1,OPRL1,PDE4D,SERPINI1,PDZRN4,POU6F1,PPP2R2B,RFX2,RGS12,KCNIP1,PKNOX2,SYT1,TK2,TLR4" Drug 6733_DN "Zidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ARHGDIG,ARRB2,MARK4,ASPH,ALDH7A1,KIF1A,ADAM23,WHRN,PPP6R2,MFAP3L,RUSC2,SPOCK3,DNM1,SORBS3,SEMA4D,FYB1,ZNF44,SEPT9,AHDC1,POLL,PSRC1,GPER1,MAPT,ZNF862,MYT1,NUCB1,OGG1,FSD1,MAPK7,FAM120C,KHDRBS2,RGS4,RGS10,KIRREL1,RXRA,MAPK12,SBF1,ARHGAP26,SPTAN1,PHLDB1,RPGRIP1L,DOCK9,TNS2,TNS1" Drug CID000002118 alprazolam Stitch 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ACHE,AP2A1,CALB1,CALB2,CH25H,CDH8,CHRNA4,CHRNB2,TOX,WDR20,DTNA,AASS,EPB41,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,CYP46A1,GFAP,LOXL3,GRIK1,GRM2,MAOB,MOBP,NPY,NTRK3,ABCB1,GPSM2,PTAFR,RAB5B,RXRG,SYBU,TCEA1,ZEB1,SLC17A7,SLC17A6,EPM2A" Drug 2505_DN Ricinine [524-40-3]; Down 200; 24.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ABAT,ADORA2A,ANK2,CDK13,SLC4A4,SYNJ2,LDLRAD4,CAMK2G,CAPN3,CCNT1,SIPA1L1,SMG7,SPOCK3,TOM1,FAM13A,MTSS1L,PDLIM5,SRCAP,GNG3,LILRA2,MAP4,MGAT3,MIA2,NF1,NNAT,PLTP,LRRN3,FAM120C,RAD52,RNASEL,PLPPR3,FAM102A,MYH15,KDM4C,RBM26,DIP2A,AHCYL2,TMOD1,PARD3,CABIN1,FLRT2,ZNF32,PRDM2,NT5M" Drug 5432_DN Fenoterol hydrobromide [1944-12-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ASPHD1,ATM,BCL7A,SYNJ2,KYAT1,MAGI1,FAM189A2,HOMER3,ABI3BP,ENTPD4,SOCS5,PPP6R2,DAPK3,MFAP3L,C2CD2L,DNM2,ACSL4,ZNF589,GPD2,GPM6B,GPER1,HNMT,KHK,KPNA5,MPP2,SERPINE2,PTHLH,RAD52,SEC14L1,ZFP30,SLC6A8,RBM34,EMC1,SPART,COBL,MCF2L,EXOC7,KIAA0930,RPGRIP1L,PARD3,PLPPR2,SPHK2,REEP1,SEMA3B" Drug 997_UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "C1QTNF3,KCNAB2,APC,PPFIA3,MARK4,CFLAR,SGCE,C5,BAIAP3,CNTN1,TENM4,LRIG1,ARMCX2,TOM1,SIDT2,MTSS1L,F5,COPS8,HTATSF1,POLL,NR3C1,INPP5B,LSS,MAP2,LYRM9,ZNF862,NAP1L1,CNOT4,PTPA,GRAMD1C,FAM184A,RPS20,PREX2,PPP4R3A,SLC6A8,SLC15A2,VAMP1,VPS13A,PLCB1,PSD3,VAV1,PRDM2,EPM2A,GAN" Drug 4136_DN Niclosamide [50-65-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ABHD6,KIDINS220,NME5,AK2,APLP1,PDE8B,BMP7,SCAPER,GYG2,FOXN3,B4GALT6,LHX2,ARMC8,MAML1,DBT,EFNA3,RBM12,EPB41L1,ZNF589,OLFM1,FGFR3,GALC,GPR19,BTN2A1,IDH3A,BRINP3,DIPK1A,KCNH2,KHK,MAP4,MAPT,NAP1L2,STRN3,PTHLH,ZDHHC14,RET,FBXO11,JMJD6,POPDC3,NDRG4,SYNC,MAP3K12,EMSY,MVB12B" Drug 4978_UP Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "NDRG2,ADD1,AGT,PPFIA3,SEMA4G,ARRB1,CDK13,CALB2,EPS15L1,HOMER3,ARHGEF6,ARHGEF10,EDNRA,ZNF589,GPER1,PCLO,HSF2,KCND3,MAP4,MMP16,NOVA2,NUCB1,TRHDE,PPARA,GON4L,ELOVL2,ZMAT4,CARF,FUZ,ST6GAL1,SNCA,KDM4B,IQSEC2,NXT2,POPDC3,PCDHGA10,PCDHA5,TMOD1,CABIN1,TRIO,HIRA,LAT2,EMSY,ADAMTSL3" Drug 4118_DN Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ADORA2A,MRTFA,AMPD3,ARHGDIG,ATM,CFLAR,PLEKHB1,NMT2,GREB1,DSCAM,TOM1,KAT8,ZNF589,ZNF44,GALC,TXNL4A,CNTRL,ELOVL5,JAK2,KCNH2,MAP4,MDM4,ADAM22,NFYA,NTRK2,PDE3B,SLC25A23,MAPK8,WDR25,PLPPR1,ATG16L1,ZCWPW1,TCP11L1,ZNF821,AMBRA1,ABLIM3,WDTC1,UNC5B,KAT6B,ZMYND8,UBTF,FTSJ1,WNK1,EPM2A" Drug 3608_UP Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.12E-03 1.00E+00 3.13E-02 3.56E-01 44 193 "ADRA1B,DDO,APOC1,ASCL1,MARK4,GYG2,CACNA1D,SYNGR3,CRHBP,CSF1,RIMS3,SPOCK2,EDIL3,FEM1B,EFNB3,HSD17B14,ERCC2,FGFR3,CAMSAP1,SCARA3,HPCAL4,RND1,GUCY1A1,KLF12,KIF5A,MBP,MID1,MYH7,NELL2,NF1,PALM,CEP41,SLC1A7,PKNOX2,SLCO1A2,SPTB,PHLDB1,VAMP1,ARC,ROBO3,TRIM2,THBS4,TTPA,TUBB1" Drug ctd:C014949 acetylhydrazine CTD 6.14E-03 1.00E+00 3.14E-02 3.57E-01 19 67 "KRIT1,SPOCK3,EFNB3,ZIC4,FGF14,CELF1,MAP6,ODF2,ANLN,PILRA,POLG,MAPK10,SCN3A,ZNF334,TNIK,STXBP1,ZFP91,VAV2,HRASLS" Drug CID000002766 trans-4-aminocrotonic acid Stitch 6.14E-03 1.00E+00 3.14E-02 3.57E-01 19 67 "BCS1L,CLCN3,CLCN4,COL4A5,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GRM5,MGAT3,SLC6A1,SLC6A11,SIRT2" Drug 1865_DN Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.28E-03 1.00E+00 3.21E-02 3.65E-01 43 188 "ASIC1,AK2,ATM,STX16,CFLAR,SYNJ2,LRRFIP1,DBN1,SPATA2,SUGP2,PDLIM5,FAM49B,OGA,HBS1L,DIDO1,ITGA7,JAK2,MKLN1,NF1,SMIM7,ZNF426,RC3H2,POLG,PRKCZ,SNRK,BTBD7,ZCCHC24,ARHGAP26,SPTAN1,POGZ,SS18,MAPK8IP3,CEP68,DIP2A,PJA1,EXOC7,TCF4,DMXL2,TNS1,ZMYND8,EMSY,NT5M,IFT88" Drug 2000_UP Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; HL60; HG-U133A Broad Institute CMAP Up 6.28E-03 1.00E+00 3.21E-02 3.65E-01 43 188 "ADD3,PLA2G6,APAF1,GAS7,RIPK1,CACNA1A,CD86,RCBTB2,SRSF11,TJP2,PPP1R16B,FBXL5,LPAR6,ING4,SARAF,STAG2,NXPH3,MPP2,NAP1L1,NTRK2,PDE4B,GPSM2,PLCD1,PTN,ARID4A,RGS12,ATXN7,ITSN1,SLA,ARHGEF40,SLC11A1,KBTBD4,KDM4B,EPB41L3,STX1A,VAMP1,ANKRD12,ATMIN,TK2,TNFRSF1B,HIRA,ZNF32,EVI5" Drug 887_DN celastrol; Down 200; 2.5uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.28E-03 1.00E+00 3.21E-02 3.65E-01 43 188 "ADCY6,ATP6V0A1,GYG2,RAB26,AKAP12,MICAL2,CTNND1,DCAF8,RIMS3,GIT2,DLG3,TRAPPC9,RBM12,CELSR3,MRNIP,EFEMP1,DLC1,TMEM164,CAMKK2,GART,PRRC2B,GPR19,DIDO1,IPO5,MATK,NASP,PIK3R1,MAPKAP1,RETREG2,PRKAR1B,RAB5B,MCMBP,LGR4,TRAPPC13,MAPK12,EPN2,SLC15A2,DICER1,METTL3,TRPS1,ZMYND8,LMF1,PHTF2" Drug CID003476986 blebbistatin Stitch 6.39E-03 1.00E+00 3.26E-02 3.71E-01 29 116 "ACTN1,MYH7B,WASF1,CACNA1A,RHBDL1,PRC1,CD38,CDC42,MYL6B,ABI2,PTK2B,ACTL6B,MYLK2,AFDN,MYH3,MYH6,MYH7,MYL3,MYO5A,MYO6,MYO7A,MYO9A,ANLN,PTK2,MYH14,MYO18A,SLC12A2,ACTR6,RGMA" Drug CID000517273 montmorillonite Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "KRIT1,SOCS6,CDON,DNER,MX1,PCDHGC3,SOX10,PCDHGC5,PCDHGB7,PCDHGA11,PCDHGA10,PCDHGA3,PCDHGA2" Drug CID000062714 Li-H Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "AK2,CASK,MAGI1,AK5,EDN1,EEF1A2,AASS,COPS8,IGF1,LMO2,PMP2,CLSTN2,ABCC8" Drug CID000085255 epps Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "ACHE,CHRD,BCHE,BSN,CACNA1B,CACNA1E,CACNA2D1,CHRM1,SV2A,KCNH1,RYR3,PEG10,EPM2A" Drug CID000381235 AC1L8GZ1 Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MX1,ABCB1,GSTCD,TUBB2A,TUBB1,TUBA1A,EPM2A" Drug CID000005210 sibutramine Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "ABHD6,CACNA2D1,SLC25A14,CCK,CNR1,FHL1,GNAS,HTR2A,KCNC1,KCND3,KCNH2,NPY,PDLIM2" Drug CID000122124 AC1L3U0V Stitch 6.43E-03 1.00E+00 3.29E-02 3.74E-01 13 40 "CALB1,ARNT2,PTK2B,B3GAT1,FYN,DDX19B,KCNB1,LIG4,MTTP,MYH6,PTK2,TACR1,XRCC4" Drug CID006102740 C-1b Stitch 6.44E-03 1.00E+00 3.29E-02 3.74E-01 20 72 "ADCY8,ADRB2,DGKZ,DGKD,DGKI,CHRM1,DGKB,DGKG,RASGRP1,CALCRL,PSIP1,KCNMA1,PKD1,PRKCB,PRKCG,PKN2,PRKCZ,PRPH,GSTCD,VAV1" Drug CID000447401 1nmk Stitch 6.44E-03 1.00E+00 3.29E-02 3.74E-01 20 72 "MRTFA,PROM1,VCAN,WDR20,TENM1,CALCRL,F3,GFRA1,CRCP,STON1,GRIA2,IGF1,IL6R,MAT2A,MSRA,FEZF2,FNDC3A,SOX2,TF,TJP1" Drug 2423_DN Digoxin [20830-75-5]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.44E-03 1.00E+00 3.29E-02 3.74E-01 42 183 "ST3GAL5,CBR1,KRIT1,CLCN3,SLITRK5,CX3CR1,DBT,RHOBTB1,KBTBD11,RBM12,FAM13A,ING4,PLEKHO1,ZNF589,CAMSAP1,DIDO1,IFI16,KIF2A,MIA2,NEK1,NF1,NLE1,SAMD9,PTAFR,PTCH1,ST6GAL1,SLA,SPATA7,CLUAP1,GLT8D1,ZNF302,NCDN,CEP68,SYT11,ATMIN,TCF7L2,TNNT1,ZNF23,ZNF32,HPS4,EPM2A,MARCH8" Drug 1154_UP 17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.44E-03 1.00E+00 3.29E-02 3.74E-01 42 183 "APBB2,APP,CFLAR,CAST,MAP7,CREM,CRY2,EDRF1,TBC1D5,DAPK1,DBT,KIAA0753,RUSC2,DTNA,FAM13A,MBNL2,SORBS3,CAP2,CAMKK2,DISC1,KCNMB4,NAP1L2,NINJ2,PDE4B,MBOAT7,PRKACB,PTK2,RPS6KA2,HSPA4L,ITSN1,NUBPL,BTBD7,IQSEC2,EXOC7,TCF7L2,TK2,KAT6B,LMF1,ZNF32,MPPE1,PHTF2,FXR1" Drug 6937_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.44E-03 1.00E+00 3.29E-02 3.74E-01 42 183 "BIN1,PPFIA3,CADM3,KIF1A,SCARB1,DNAJB5,ARHGEF6,FEZ1,MICAL2,DZIP3,ARHGEF4,EDRF1,SGK2,HSD17B14,COQ7,DENND4A,REEP2,EFEMP1,GABRA2,INPP5K,CACFD1,NR3C1,ELOVL5,ITGA7,NAP1L2,NUCB1,POU6F1,ZNF821,HSPA4L,SGK1,SH3BGR,KDM4B,SPTAN1,IQSEC2,TSPYL2,NXT2,ARHGEF9,POPDC3,TRO,DNAJC12,VLDLR,ACTR3B" Drug CID000644241 nilotinib Stitch 6.49E-03 1.00E+00 3.31E-02 3.77E-01 17 58 "ABHD6,BRAP,CNTNAP1,ABCG2,CSF2RA,EPHB1,FGFR1,FGR,JAK2,KIT,KITLG,NTRK2,PDGFRA,LAMA1,RET,TEK,FIP1L1" Drug 3141_UP Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.50E-03 1.00E+00 3.32E-02 3.78E-01 37 157 "ABHD6,TKTL1,GRAMD1B,MTUS1,BIN1,DNAH17,CD86,CD38,CHN2,WHRN,CREM,MICAL2,SIPA1L1,PDE4DIP,PPP1R16B,DOCK4,FAM13A,SORBS3,PRKAG2,OLR1,PDE4B,PDE4D,SERPINI1,SMOX,NECAB2,QDPR,TMEM255A,SATB1,GALNT10,SGK1,ARHGEF40,BEX1,SPTAN1,RAP1GAP2,PLCB1,TRPS1,FLRT2" Drug 7281_UP Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "GAS7,APP,CDK13,CFLAR,SYNJ2,RUNX1T1,CACNA2D2,PLEKHB1,CHRNB2,QKI,LY86,AKAP7,IFFO1,CRY2,TOX,GIT2,JAKMIP2,EDNRA,ZNF589,FGFR1,SORBS1,FYN,GAB1,GRM1,SHISAL1,TJAP1,KCNMA1,KIF5C,ZNF862,PFKFB2,POLG,SNRK,RGS3,TTLL7,ZNF821,SH3BGR,AMBRA1,SLC1A7,THSD1,SEPT8,SYNE1,TIAM1,PARD3,ZMYND8,TIGD6" Drug 4534_DN Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,MTUS1,MRTFA,PKP4,APC,MARK4,MTMR9,CBFA2T2,CDH10,NRXN3,HAPLN1,SDC3,DCAF8,RCAN1,PLXNC1,MRNIP,ANKMY1,F3,SEMA4D,FYN,TRAF3IP2,SRCAP,GLS,GRK4,TJAP1,INPP5B,MAN2A2,GIT1,MYO6,SLC11A2,PIK3R1,KCTD15,PRKAR1B,RPS6KA2,TRAPPC13,MYH15,DDN,IQCE,TCF4,SZT2,RUNDC3B,OSBP2,EMSY,NT5M,NAV3" Drug 6636_DN Harpagoside [19210-12-9]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "PPFIA4,APC,CDK10,CDK13,KIF1A,SYNGR3,TAOK2,HOMER3,WHRN,CPS1,CSF1R,EDRF1,MAMLD1,SORBS3,TUBD1,ETV1,FGFR1,ZNF44,INPP5K,POLL,GPR19,HSF2,IL6ST,ITGA7,MMP16,NF1,PFKFB2,PPARA,GRAMD1C,FBXW7,ZNF821,ITSN1,BCAN,WDTC1,EMC1,DDN,SS18,RPGRIP1L,GPR161,PARD3,TPM2,TRPC1,XRCC4,EVI5,EPM2A" Drug 2830_DN Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ALCAM,AMPD2,KCNAB2,APC,EPB41L5,BMP7,PLEKHB1,EPS15L1,ABCG1,FEZ1,CSNK1E,DZIP3,CTNND2,TBC1D5,RIMS3,DTNA,MAMLD1,EPB41L1,STX2,IQCG,GRB10,CACFD1,PADI2,HNMT,ITPKB,MAPT,NUCB1,PLEC,PRPH,ZCWPW1,TCP11L1,WLS,RXRA,FOXRED2,ANKRD6,DHX30,KDM4B,ITPRID2,NCDN,WWC1,TIAM1,HIRA,NSD2,MAP3K12,SMIM8" Drug 4277_UP Heliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "KLRC4,CDC14B,CDK10,ZSCAN18,BMPR1B,MTMR3,P2RX6,CD86,NEURL1,CNTFR,COL9A3,CSF1R,CTNND2,RIMS3,HEPH,ECM2,ELN,KCNMB2,ZNF549,DLC1,ZMYND10,FOLR2,SIGLEC8,GRM2,KCNB1,KHK,MAP2,MMP16,NCAM1,NF1,NTRK2,PBX1,ABCB1,VPS13C,MARCH1,RASGRF1,RFX2,RGS12,KLHDC8A,PRR5L,SLN,ATP10B,TIAM1,UBE3A,EPM2A" Drug 4633_UP S(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ALK,MRTFA,APC,KSR1,THSD7A,HAP1,ADGRG1,PLAA,TPP1,PDE4DIP,DBT,CNIH3,AK5,SGK2,HIPK3,FCF1,ETV1,PDLIM5,FYB1,SIGLEC8,CSDC2,GLYR1,GNG4,LPAR4,GRK4,HLF,IL6R,JAK2,AFF1,P2RY13,KCTD15,CNKSR2,ANKRD6,KANSL3,SLC11A1,SNCA,ZHX3,PEG10,ARHGAP26,PHLDB1,MCF2L,FBXW11,PARP6,MVB12B,PHTF2" Drug 1157_UP LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "APBB2,GAS7,APP,FOXN3,CREM,CTNND1,DTNA,CNNM1,EFNB3,PLXNC1,EIF4G2,SORBS3,MRNIP,VPS13B,F5,CAMSAP1,PDLIM5,ZMYND11,INPP5K,ALDH1L1,HPGDS,SCAMP5,POLG,MAPK8,RELN,PTK2,PEX5,TMEM231,RET,TCP11L1,SH3BP2,ITSN1,THSD1,ZC4H2,VAMP1,PLCB1,KIAA1107,TMOD1,RBFOX2,TPM1,PLPPR2,SYNC,KCNAB1,MPPE1,PHTF2" Drug 2802_DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,ABHD6,APOC1,ARHGDIG,ASPH,ALDH4A1,ATP6V0A1,CFLAR,BTRC,CA4,NMT2,AKAP12,SIPA1L1,GPRASP1,FBXL5,LYPD1,RCAN1,GNE,DTNA,TNK2,ENO2,ACSL4,KAT8,FECH,PDLIM5,DIDO1,HNMT,ITPKB,ZNF862,PC,PDE4A,PRPH,ZSCAN32,PTPRE,NKAIN1,NEK11,SLC1A7,DHX30,COA1,VPS13A,PLCB1,TACC1,DMXL2,ZMYND8,EPM2A" Drug 1325_DN Lysergol [602-85-7]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "C1QTNF3,N4BP2L1,RIPK1,BCL2L2,ENTPD6,UBE2L6,CLCN4,IQCK,COL9A2,VCAN,DBT,DPH1,RABEPK,VPS26C,F8,FCGRT,ATP2C1,MPP6,OGA,INPP5K,ICA1,TJAP1,LIG4,MAP4,NF1,SETD4,OCRL,PLEC,GTDC1,EXD2,GSTCD,CCDC25,ZBTB43,TROVE2,THSD1,FCHO1,VAMP1,FBXW11,TCF4,TPD52,METTL3,NPDC1,WNK1,MPPE1,PHTF2" Drug 7541_UP 16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "SEMA6A,ATP1A3,BMP7,INA,NEURL1,CDH18,MAGI1,VAX2,IQCK,DZIP3,CTIF,HP1BP3,DRP2,DSCAM,DTNA,ELAVL3,DMTN,FLT1,GPR153,PCDH17,GLYR1,GPR12,GPER1,GPR37,INPP1,KIF5C,LMO2,LSS,MMP16,CAMKV,RETREG1,PPP3CC,ELOVL2,RAB3IL1,NEK11,EMID1,TCF4,KIAA0930,PSD3,RBFOX2,CDK20,METTL3,LMF1,SLC17A7,SSPN" Drug 6830_DN Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,ALCAM,DOC2A,ATM,MTMR9,BTRC,CLCN3,COL9A2,SDC3,JAKMIP2,DNM1,DTNA,EXTL2,EZH1,ZNF589,PRELID3A,GLS,CACFD1,PADI2,IDH3A,IGSF1,KIF2A,GIT1,PDE3B,RETREG1,PLXNB1,PPP5C,PRODH,ELOVL2,RAB3A,RAB3IL1,FUZ,ANKRD6,SLC1A7,SLC22A4,SNCA,FNBP1,ERC1,IQSEC2,ASTN2,MCF2L,TMEM121,TK2,WNK1,EPM2A" Drug 7422_DN Nortriptyline hydrochloride [894-71-3]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "APBB2,NCOA1,ATM,CFLAR,BMP7,TAOK2,CLCN3,STOML1,COL4A5,SMARCAL1,CREM,SOCS5,PDE4DIP,KIAA0586,HP1BP3,DTNA,SUGP2,EML1,EFEMP1,CGREF1,OGA,GPR37,SCAMP5,MITF,NACA,PRKAR1B,ZCWPW1,FERMT1,ZNF365,SLC15A2,BTBD7,ZKSCAN3,PDZRN3,KDM4C,PHLDB1,FAM168A,ARHGEF9,WWC1,SATB2,TCF7L2,KAT6B,TRPC1,RPRM,PRDM2,MPPE1" Drug 2144_DN Protoveratrine A [143-57-7]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "APP,SYNJ2,CACNA1A,CNTN1,ENTPD4,VCAN,RIMS3,DGKG,SGSM2,RASGRP2,ZNF589,FHL1,FLT1,AFF2,USP19,GLYR1,GPD2,KCNJ5,GIT1,MYT1,P2RY1,CCSER2,SMOX,PILRA,POU6F1,CNNM2,PTPRN2,PEX5,RAD52,CCDC25,SH3BP2,EPN2,SLC11A1,SLC15A2,DOK5,IZUMO4,UNC5B,PLCB1,PDLIM2,TMOD1,KAT6B,ZNF32,ZBTB38,GDPD5,PHTF2" Drug 4297_UP Karakoline [39089-30-0]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,ASIC2,ADD2,ANK3,PKP4,KCNAB2,APC,AQP4,AQP6,BMP7,CACNA2D1,CAST,RUNX1T1,NEURL1,HOMER3,ABCG1,CNTNAP2,CYBB,DCT,EDN1,ING4,KCNMB2,IGSF6,TBR1,GPM6B,LPAR4,SPACA9,PTPRT,PTGDR2,HTR2A,IL6ST,AFF1,PDGFRA,PRKAR1B,PTPRN2,RET,ROM1,DZIP1,SCN3B,MCF2L,TEX15,TMPO,CADM1,LAT2,EPM2A" Drug 3696_DN Cefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AMPD3,AMT,APAF1,APC,TAOK2,CNTN1,IFFO1,NCOR2,ARMCX2,CNIH3,DSCAM,RCAN1,DTNA,PLXNC1,MRNIP,ELN,LRRC23,NCALD,SORBS1,FYB1,SRCAP,INPP5B,ITIH2,KCNMA1,KCNQ3,KHK,MAN2A2,ADAM22,MT1M,TAGLN3,PCDH9,PPARA,CCDC40,RAD52,RGS10,RGS12,ZNF671,PKNOX2,UNC5B,DDN,COLGALT2,ARHGEF9,IQCE,TCF4,CDK20" Drug 5259_DN 3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADRA1D,APBA2,APBB2,DNAH17,ATM,ALDH7A1,CFLAR,CFAP410,ARMC8,COL9A2,PDE4DIP,PLEKHO1,SCML2,CAMSAP1,FAM49B,GPR153,GAB1,INPP5K,GNG3,GPER1,SLC2A6,MUM1,IL6ST,MAP4,ADAM22,NPR2,RETREG2,PRKAR1B,WDR25,RGS3,RPS6KA2,SEC14L1,EPN2,SLC9A5,RBM34,ZCCHC24,MCF2L,KIAA1107,TBCEL,WSCD1,CHST8,ZIC3,ZNF45,PRDM2,SEMA3B" Drug 6357_UP Condelphine [7633-69-4]; Up 200; 8.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADCY6,ADGRF5,ALK,APAF1,APBB2,SEMA4G,DNAH17,IL33,CACNA2D2,CNOT8,NCOR2,AATK,KBTBD11,CDON,EDIL3,FAM13A,EGFR,IRAK4,EZH1,ERAP1,SRCAP,PCDH17,INPP5B,KIT,LIG4,VWA5A,NELL2,NF1,NFYA,NUMA1,PPARA,LRRN3,PLPPR1,ACSS3,GAL3ST4,NEK11,SMPD3,ZFP30,SLC1A7,KDM4C,ARHGAP26,ARHGEF12,FRYL,RUNDC3B,SMIM8" Drug 1719_DN Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ST3GAL5,PTBP2,RUNX1T1,KRIT1,EPS15L1,NCOR1,ARHGEF10,RUBCN,SPOCK2,TRAPPC9,KCTD3,KIAA1109,PRKAG2,SEC23B,C1orf61,IP6K2,GLYR1,ELOVL5,IDH3A,INPP5B,MAP4,MPP2,NOS1,SERPINE2,RETREG1,PLCD1,RAB3IL1,BSDC1,GTDC1,ZFP30,FBXO11,SLC2A5,EMC1,SYT11,TACC1,DMXL2,AHCYL2,NACC2,LAT2,XRCC4,REEP1,FTSJ1,PARP6,EPM2A,ST7" Drug 641_UP benserazide hydrochloride; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BCAR3,APBB2,AQP6,BRINP2,ATP2A2,BCL7A,C5,CNTFR,SLC4A7,HINFP,SDC3,DCAF8,ACOT8,RCAN1,EFNB3,MBNL2,ERCC2,EFEMP1,FECH,OLFM1,BAIAP2,SEC23B,SEMA4D,DCTN2,GPER1,RNFT2,ARHGAP19,KCNJ5,IPO5,MBD1,ADAM22,NUCB1,PFKFB3,PIK3CD,MAPK8,RGS12,ITSN1,PPP4R3A,RAB3GAP1,KBTBD4,SLC15A2,ELMO2,PLCB1,TBL1X,AAAS" Drug 380_DN tamoxifen citrate; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADORA2A,MTUS1,ALAD,PPFIA3,CDC14B,PDE8B,CADM3,JAM2,RAB26,IQCK,RIMS2,HS3ST2,SIDT2,SORBS3,GPR153,FYB1,ZMYND11,PRDM5,SOX21,KCNJ3,MBD1,MYT1,NOS1,OCRL,SMOX,MBOAT7,MED1,MAPK3,PRPSAP2,C1orf109,RNASE1,ZC3H14,URGCP,EMC1,ATP10B,ZC4H2,FCHO1,STXBP1,ANKRD12,WWC1,ARHGEF12,HIF3A,GORASP1,ZBTB16,WNK1" Drug 6795_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "DPF1,ARID1A,BIN1,CFLAR,GYG2,BAIAP3,CHRNB2,EPS15L1,GREB1,DCAF4,DBN1,RUSC2,DUSP9,EGFR,TNK2,FHL1,SCARA3,SORBS1,GPR153,GFER,IRF8,IL6R,MAG,ADAM22,NPTX1,CDK14,PGAM2,PIK3CD,NLE1,MAPK8,RAD51D,CRTAC1,RGS12,KLHDC8A,ASAP3,SYBU,SPTAN1,TACC1,SEMA4A,DOCK9,PSD3,TGFBR3,TPM3,SLC30A3,PRDM2" Drug 6217_UP Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,ARID1A,NDRG3,APOC1,PPFIA3,ATP2A2,CADM3,CDK5R1,FOXN3,HAPLN1,LRIG1,MFAP3L,ATN1,ENO2,EFEMP1,AFF2,GAD1,NCKAP1,ALDH1L1,CNTRL,CACFD1,RNFT2,IL6ST,MATK,NNAT,CNOT4,PRKAR1B,ELOVL2,PTPRG,ROM1,NEK11,TCP11L1,SGK1,SMTN,SLC9A5,ZCCHC24,ZBTB43,NXT2,PLCB1,CHST8,ZMYND8,MICAL1,ST7,NUP214,SSPN" Drug 346_DN 2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "RBM10,KDM5D,ADD2,BRAP,KCNAB2,GAS7,CDK10,ARSF,NCOA1,SLC4A4,ATP6V0A1,BCL7A,BMPR1B,CHRNA4,EXOG,MED12,ATN1,EFNB3,ING4,COQ7,LRRC23,TRMO,KHDRBS3,BTN2A1,NACA,NPPA,SETD4,C1orf109,ARHGEF10L,TCP11L1,FOXRED2,FERMT1,ZHX3,EMC1,ZC3H13,MLST8,TBL1X,CRTC1,THBS4,KAT6B,ZKSCAN5,UBTF,ZIC1,ZNF74,MPPE1" Drug 6262_UP Azlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "APBB2,PDE8B,CFLAR,SCAPER,GYG2,RCBTB2,CHRNA4,VAX2,QKI,CSF1R,ARHGEF4,CTIF,DCT,CNNM1,EGFR,RASGRP2,FGF12,SEMA4D,NEU3,SRCAP,TXNL4A,GLYR1,EML4,GRIK5,HAS2,ATXN2L,IL6ST,KCNMA1,MGAT3,ADAM22,NF1,SLC11A2,RETREG1,PLCD1,SAMD9,GON4L,PTCH1,ATP10B,PHLDB1,PLCB1,CABIN1,TRPM2,FAM155A,PHTF2,TIGD6" Drug 3063_DN 2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AGT,AMPH,ASPH,SLC4A4,AZGP1,SYNJ1,CACNB4,HIP1R,CLCN4,FAM149A,C3orf18,FER,GAB1,ZMYND11,ADAM28,LILRA2,SPACA9,GUCY1A2,KHK,GIT1,MYO7A,NOVA2,PDE4A,SLC25A23,MTRF1L,PILRA,PROX1,FAM120C,TCP11L1,SYNDIG1,SNCA,ZNF415,KDM4B,DOP1A,SYN2,SYT1,IQCE,TCF7L2,KAT6B,TRPS1,ZMYND8,FLRT2,ZNF32,ST7,SSPN" Drug 5504_UP Lisinopril [83915-83-7]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "SYN3,FZD9,AMT,APBA2,GAS7,DDO,SCAPER,DCLK1,CLGN,NRXN2,CREB5,CSF1R,USH1C,PIPOX,CORO2B,ZNF589,FHL1,FYN,GRB10,SHISAL1,VWA5A,ZNF862,NFYA,NRGN,NTRK2,OPRL1,PLCD1,MTRF1L,LRP12,PROX1,RALGDS,ZDHHC14,SBF1,ASAP3,SYBU,ARHGEF40,SMARCD3,ZSWIM8,IZUMO4,KDM4C,ZC3H13,EPB41L3,WSCD1,PCDHGA1,CABIN1" Drug 4608_UP Betaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABAT,CDC42BPA,APBB1,ATP2B3,CBLN1,SLC16A4,DLGAP1,CABP1,RIMS3,AK5,DTNA,SGK2,SIDT2,RCAN2,ETV1,KIAA1109,AGAP2,GNAO1,GNG4,GPM6B,GPR22,GRM7,GRM8,AP4S1,KCNJ5,LSS,MDFI,MYO7A,NPPA,PDE4D,MTRF1L,PRPH,RASGRF1,RASA3,DOP1A,BEX1,ASTN2,TACR1,ADGRL3,TEK,TLL2,PRDM2,SLC17A7,KCNAB1,SENP7" Drug 2252_DN Piroxicam [36322-90-4]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BIN1,GAS7,FAM131A,APOC1,PPP4R4,PLA2G4C,RASL11B,SLC4A4,GYG2,CA4,ARHGEF2,VAX2,CNTN1,DCAF8,PARD6A,DSCAM,PLXNC1,SORBS3,LRRC23,HBS1L,STON1,SPACA9,GRIK5,GSN,VWA5A,MYT1,MAPK8,PRODH,TMEM104,FAM120C,SEC14L1,ZNF821,BCAN,CXXC4,SNCA,WDTC1,TROVE2,MAPK8IP3,VAMP1,ARC,PDLIM2,PSD3,TNS2,CABIN1,EMSY" Drug 3446_DN Proadifen hydrochloride [62-68-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AP1B1,AK2,ARRB1,CFLAR,GYG2,BTRC,CFAP410,CBR1,UBE2L6,RAB28,QKI,DCAF8,MFAP3L,PARD6A,DNM1,TRAPPC9,HIPK3,FCF1,EIF4G2,ENO2,LRRC23,STX2,BAIAP2,CAMKK2,GLYR1,RAB30,GLUL,EML4,HSD17B1,KCNJ3,CNOT4,NPR2,NRGN,POLR2F,SAFB,TRA2B,ABLIM3,ATP11A,SEMA4A,TMPO,KCTD2,CDK20,PLPPR2,PHTF2,RNF170" Drug 5265_DN Clozapine [5786-21-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABHD6,NDRG2,ALCAM,APP,DNAH17,ALDH7A1,CADM3,NRP2,LDLRAD4,CRLF1,ARHGEF4,RASSF2,CDON,EFNA3,MBNL2,EN2,DMTN,DLC1,FGFR1,FHL1,DISC1,RAB30,GNG3,GRM8,IL6ST,KCNQ3,KIF5A,KITLG,MOBP,BCO1,NF1,SETD4,NLE1,PPP5C,RGS10,CXXC4,SNCA,ZCCHC24,ST5,ARC,TBCEL,PCDHA5,TK2,CDK20,LMF1" Drug 4562_DN PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADD2,ALK,KCNAB2,APBB2,APC,CDC14B,PDE8B,KIF1A,CACNA1I,CDH10,NRXN3,AKAP7,NCOR2,MFAP3L,EFNB3,TENM1,HSD17B14,CDKL3,SRCAP,GRIK2,SPACA9,HLF,KIFC3,MDFI,GIT1,MT1M,MYO7A,NDUFA5,CNOT4,NTRK2,CLDN11,PRKAR1B,SAMD9,FBXW7,RPS6KA2,ST6GAL1,MAPK8IP3,PHLDB1,SLC44A1,AMACR,ZMYND8,CADM1,RPRM,NDRG4,KCNAB1" Drug 1889_UP Dibucaine [85-79-0]; Up 200; 11.6uM; PC3; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "PPFIA3,MARK4,CADM3,ATP6V0A1,ARHGEF7,ARHGEF2,FOXN3,SLC4A7,CSNK1E,CST3,ARHGAP32,TM9SF4,GIT2,RUSC2,C2CD2L,KLHL3,KBTBD11,EFNA3,TNK2,TMEM8B,DISC1,HTATSF1,CACFD1,MX1,MYL3,NPPA,OGDH,CLDN11,PALM,RETREG1,PCMTD2,IL17RB,ZNF821,TRA2B,SH3BP2,ST6GAL1,ARHGEF40,FCHO1,STXBP1,IQCE,WSCD1,TRIM2,NACC2,CBX5,WNT7A" Drug 6287_UP Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ALAD,PPFIA3,SHROOM2,PDE8B,SYNJ2,LDLRAD4,ARHGAP33,CPS1,ABCG1,AATK,NCAN,DZIP3,NOS1AP,MFAP3L,MAGI2,EFNA3,EFNB3,LPAR6,COQ7,DMTN,CAMSAP1,DENND2A,GAD1,USP19,COPS8,STON1,GRIK5,PTGDR2,KHK,MAPT,MBD1,MSR1,CLDN11,PDGFRA,GRAMD1C,ENOX1,RGS12,SH3BP2,ZNF415,PHLDB1,FBXW11,PCDHGB6,LMF1,ZBTB14,NT5M" Drug 439_DN oxamic acid sodium salt; Down 200; 10000uM; MCF7; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BRAP,C1QTNF1,BEGAIN,CDC42BPA,APBA2,GAS7,PPFIA3,ARNTL,ASPH,CA12,CDC27,CHGB,RAB28,PLAA,STOML1,TMEM59L,IQCK,ARHGEF10,SUGP2,SORBS3,PLEKHA1,COQ7,VPS26C,SEC23B,GABRA4,GNAS,LILRA2,ARHGAP19,KCND3,NACA,CNOT4,NPR2,OPCML,RETREG1,CYBC1,CLIP1,ELMO2,SPART,LARP4,SS18,TMEM151B,SEZ6L,MPPE1,MVB12B,CERS6" Drug 6982_DN 2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ARID1A,ADD3,OSBPL1A,BCAR3,DGKD,MADD,RIPK1,MPDZ,HOMER3,SLC4A8,CREM,HINFP,PPP6R2,DCAF8,TM9SF4,DAPK3,GIT2,DNAJC6,RABGAP1L,MBNL2,MRNIP,VPS26C,CGREF1,TXNL4A,GPD2,GRB10,NR3C1,AGBL5,IGSF1,NEK1,NFYA,PPP2R5C,TMEM231,ZCWPW1,MYH14,ZFP30,CDK5RAP2,KDM4C,NCDN,MTCL1,EXOC7,WDR7,TSN,UBTF,SH3GLB2" Drug 3118_UP L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADORA1,AP2A2,LTBP4,DOC2A,APBA2,AQP4,PRX,CCDC181,SYNJ2,FUBP1,SLC16A4,CLU,CREM,CTNND2,RIPOR2,TRAPPC9,E2F5,SIDT2,EFNA3,ABI2,SORBS3,DMTN,PRELID3A,GABRA4,NEU3,GRIK5,PADI2,ICA1,AFDN,MMP16,OMG,EPN1,MAPK10,TMEM255A,ZDHHC14,ARHGEF10L,NTNG1,TACR1,WWC1,TBL1X,TRIM2,DOCK9,AHCYL2,TMOD1,CAB39L" Drug 123_DN dexamethasone; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "MTUS1,OSBPL8,OGT,PPFIA1,NRP2,BMP7,LRBA,ARHGEF2,NIPBL,PCYT1B,AKAP6,IFFO1,PREPL,AATK,ZBTB24,DPH1,SORBS3,GLS,GRIK5,HPS5,PAXBP1,MATK,MBD1,NAP1L1,NASP,NF1,CNOT4,NTRK2,CCSER2,GPSM2,SMOX,PLXNB1,POLR2F,MAPK3,SPDL1,RAD51D,SUSD4,ITSN1,FUZ,ELMO2,KIAA0930,METTL3,UBE3A,PRDM2,MPPE1" Drug 5871_DN Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "NDRG3,APBB2,APP,NCOA1,CLU,FADS2,CSNK1G3,DCAF8,DBN1,RHOBTB1,DLG3,ANKMY1,TRMO,COPS8,GPM6B,RASSF8,ARHGAP19,SYNPO,JAK2,IPO5,MAN2A2,MITF,SLC11A2,CCSER2,SLC25A23,KLK6,GTDC1,SH3BP2,SMTN,SMARCA4,TTC17,SNCA,TMCC1,BEX1,THSD1,MAPK8IP3,ELOVL4,TCF7L2,PSD3,ARHGEF12,ATP13A2,TPD52,LMF1,SMIM8,AAAS" Drug 1277_UP Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADORA3,ADRA1D,PLA2G6,CDK10,SYNJ1,SCARB1,CHN2,EPS15L1,RGS6,DTNA,ABI2,PIPOX,CAMSAP1,ANKFY1,SEPT9,GRM1,ATXN2L,HSF2,IL6R,IL11RA,INPP5B,ADAM22,N6AMT1,NFYA,SLC11A2,NUMA1,OGG1,NLE1,MASP1,TMEM104,CNTLN,PTAFR,RAB3A,ZNF493,SLC11A1,RIMS1,TROVE2,SEPT8,FBXW11,TCF7L2,PSD3,TLR4,SMUG1,MAP3K12,SLC17A7" Drug 638_UP genistein; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADD2,ARRB1,RGS11,MTMR2,CACNA1I,SRSF11,PDE4DIP,SDC3,SEC14L5,DAPK1,EXOG,GNE,ABCC9,CNNM1,EFNB3,APH1A,PLEKHA1,FECH,FGFR1,FHL1,HPCAL4,FOXF2,GNAS,NXPH3,ARHGAP19,ICA1,MEIS1,NPTX1,PAK3,PCDH9,RETREG1,NLE1,PPP2R2B,PRODH,RET,GSTCD,SGK1,ABLIM3,TMEM151B,DAAM2,WIPF1,WNK1,NAV2,FIP1L1,CAMK1G" Drug 3347_DN Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AK2,MRTFA,AMPD3,APC,ATM,B4GALT6,QKI,SH2B1,DCAF4,MAML1,MFAP3L,RABGAP1L,SUGP2,SORBS3,ING4,FER,SEMA4D,TPK1,B4GALNT1,ERAP1,GLS,GNG3,TDRKH,SPACA9,KCNJ5,VWA5A,ADAM22,CNOT4,SLC11A2,PDE3B,MAPK8,ZSCAN2,CCDC25,FBXW7,RPS6KA2,RBM34,POPDC3,ANKRD12,KIAA1107,TCF7L2,AHCYL2,VLDLR,XRCC4,HPS4,SSPN" Drug 2978_UP Quinic acid [86-68-0]; Up 200; 19.6uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ACTN2,MTUS1,MRTFA,APBB2,ATP2A2,CFLAR,LDLRAD4,SLC16A4,NEURL1,ZFYVE9,CLCN4,ARHGEF10,SMG7,TRAPPC9,DSCAM,GPR153,ALDH1L1,ZNF276,RND1,PADI2,TJAP1,KCNJ5,NUMA1,PGAM2,CCSER2,PLEC,DCHS2,PTAFR,ZDHHC14,GALNT10,FAM102A,CCDC88A,MYH15,SPTB,CDK19,TROVE2,SS18,NSFL1C,ATP11A,CAMSAP2,PDLIM2,WWC1,KCTD2,CLIP2,EVI5" Drug 5870_DN Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADD2,APLP1,APOC1,APP,CDC14B,CFLAR,C5,REPS2,CLU,IQCK,CNTNAP2,SIRPA,C2CD2L,SGSM2,CDON,FEM1B,EFNA3,FGFR1,INPP5K,GLS,INPP5B,ITPKB,MKLN1,SLC11A2,KCTD15,PRPH,ZSCAN32,FAM120C,ATG16L1,MAP6D1,SH3BGR,FNDC3A,LIMS2,ZBTB43,TTBK2,JMJD6,ATP11A,IQCE,FBXW11,NSD1,ARHGEF12,THRA,AMACR,MICAL1,KAT6A" Drug 1847_UP Carbamazepine [298-46-4]; Up 200; 17uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AMT,APC,APP,BMP7,SYNJ1,C5,MAP7,LARGE1,TAOK2,CLCN3,ARMC8,SH2B1,PDE4DIP,RUSC2,DLG3,CDON,DTNA,EFNA3,SORBS3,ING4,EIF1,EPB41L2,KAT8,ERAP1,ADAM28,KIT,NCAM1,MAPK8,WDR25,RAB3IL1,RAP1GAP,RFX2,TCP11L1,CPEB3,PPP4R3A,SLC20A2,WDTC1,DBNDD2,RGL1,KCTD2,TPD52,CLIP2,SPHK2,EVI5,PHTF2" Drug 6492_DN Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BRAP,KIDINS220,BCAS1,APP,SEMA4G,ATP2A2,SCAPER,QKI,CREM,NCOR1,ABCG1,DZIP3,GIT2,TRAPPC9,CDON,FEM1B,STX2,GPR153,ERAP1,STON1,GRIK5,KCNF1,KCNH2,MIA2,ZNF862,SETD4,SMOX,TMEM231,RPS6KA2,KIF16B,ZNF365,PEX26,ELMO2,KDM4C,ERC1,CLASP2,EXOC7,CHST8,TMOD1,CDK20,UBTF,VAV1,PRDM2,MPPE1,ST7" Drug 7233_DN Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ALCAM,CDC42BPA,CDK13,CFLAR,HOMER3,ARHGEF6,PDE4DIP,FAM169A,CTH,PPP6R2,ZFYVE16,DAPK3,C2CD2L,TRAPPC9,DSCAM,EGFR,F3,ZNF589,KIAA1109,FOXG1,SEMA4D,CGREF1,FYN,COPS8,PRRC2B,GRB10,SETD4,PDE3B,CCSER2,RIPOR1,ROBO1,CCDC25,WLS,SBF1,SH3BP2,SLC20A2,SMARCC2,UHRF1BP1L,ZBTB43,VPS13A,ARHGEF12,CABIN1,ZMYND8,MICAL1,ZBTB14" Drug 3449_UP Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "C1QTNF3,ALCAM,KCNAB2,RGS20,ATP2B2,ATP6V0A1,CACNA1I,LDLRAD4,CA4,ARHGEF1,CACNA2D2,SRSF11,DNAJB5,SDC3,MFAP3L,GNE,ING4,PDLIM5,TXNL4A,STON1,NR3C1,GRM7,IL6R,MAP4,MPP2,ADAM22,NF1,PALM,PILRA,MAPK7,SAMD9,RAB3IL1,RALGDS,ATG16L1,RGS12,EMID1,FAM214B,WDTC1,CEP68,TCF7L2,HIF3A,SLC44A1,TIAM1,ZKSCAN5,DNALI1" Drug 4601_DN 3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "MRTFA,APOC1,BRINP2,ATP1A3,BTRC,CACNA1A,CDC42,MAGI1,AKAP7,COL9A3,ARMCX2,SIDT2,EN2,ETV1,FGFR1,SEMA4D,CINP,FYB1,SRCAP,KCNJ4,KCNN1,MT1M,MX1,NDP,PDE4B,PROX1,PTPRN2,PID1,ZNF821,BCAN,ZNF667,ZHX3,BEX1,LHPP,MAPK8IP3,ATP11A,MCF2L,ADGRL3,DOCK9,ARHGEF12,THRA,VGF,LMF1,PRDM2,KCNAB1" Drug 6306_DN Ascorbic acid [50-81-7]; Down 200; 22.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "C1QTNF1,PPFIA3,CFLAR,KYAT1,CCNT1,CNOT8,PDE4DIP,PPP6R2,SPOCK3,FEM1B,SIDT2,EFNB3,RGS17,BSCL2,CGREF1,ERAP1,ARFIP1,TXNL4A,GLRB,GLS,BACH2,JAK2,KIF5C,MAN2A2,MAPT,NOVA1,LRP12,FSD1,MINDY2,PRPH,LRRC49,PTHLH,ELOVL2,BSDC1,ASAP3,EPN2,LIMCH1,UNC5B,ARHGAP26,EXOC7,DNMBP,NR2C2,TRPC1,ZNF45,URM1" Drug 5698_DN Perphenazine [58-39-9]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AK2,APBB2,APLP1,FAM131A,APOC1,CA4,CA12,CACNA1D,KYAT1,TAOK2,ZFYVE9,AKAP12,SIPA1L1,MFAP3L,DNM1,DPH1,DRD1,DTNA,EFNA3,ING4,LRRC23,FAM198B,FGF12,PRELID3A,TBR1,INPP5K,RASSF8,LSS,MPP2,ZNF862,NDUFA5,NF1,NOS1,SLC11A2,NUMA1,MAPK8,FOXRED2,SLC1A7,SOX2,TROVE2,VPS13A,TBCEL,ZEB1,RPGRIP1L,SYNC" Drug 142_DN tolbutamide; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "C1QTNF1,AMT,CNTNAP1,GAS7,APP,SLC4A4,ADAM23,CFLAR,SCAPER,CACNA1I,CACNA1D,RUNX1T1,LRBA,ARHGEF2,CHN2,CNTFR,EFNB3,EGR3,SRPK3,FGFR3,FLNC,SRCAP,C1QL1,CRCP,GNG4,GSTM5,ADAM22,NRGN,OPCML,PALM,PIK3CD,GTDC1,ASIC4,LIMS2,SNCA,TMCC1,KDM4B,WDTC1,UNC5B,CEP68,CHST5,TRPM2,CA14,CADM1,PRDM2" Drug 6511_DN THIP Hydrochloride; Down 200; 22.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABHD6,C1QTNF3,APC,CDC14B,CDK10,SYNJ2,MTMR2,PLAA,NRG2,CREM,DZIP3,DAPK3,GIT2,CDON,OPTN,EGFR,SORBS3,LRRC23,DPYSL4,AHDC1,CNTRL,GRIK5,GRM1,KCNH2,KCNJ3,PPP5C,RIPOR1,EMID1,FOXRED2,SBF1,PKNOX2,RBM34,ZC3H13,TSPYL2,THSD1,CEP68,TCF7L2,CHST8,TMOD1,VLDLR,CLDND1,SYNC,PCBP4,MPPE1,ST7" Drug 2039_UP Haloperidol [52-86-8]; Up 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "NDRG2,SYT13,APBB2,SHTN1,SCAPER,RAB29,CAST,KRIT1,SLC4A7,SOCS5,CTH,RCAN1,RASGRP2,ETV1,ACSL4,SUCO,SEC23B,ATP2C1,OGA,STAG2,ARFIP1,CRCP,GLYR1,LILRA2,IRAK3,MPP2,NUMA1,ENPP2,ZNF426,TRHDE,LRP12,RETREG2,PPM1B,MAPK10,PCMTD2,LGR4,AP1AR,KBTBD4,ELMO2,ZC4H2,KLHL7,TCF4,TCF7L2,WASHC4,TSN" Drug 265_UP prednisolone; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "RBM10,CBFA2T2,REPS2,ARHGAP22,PCYT1B,SH2B1,PDE4DIP,CTNND2,CTIF,GIT2,FBXL5,SUGP2,CALCRL,FHL1,DENND2A,NCKAP1,LILRA2,GPR37,GRK4,SOX21,ARHGAP19,AGBL5,KCNC1,ADAM22,MYL3,NELL2,NRGN,OPRL1,FSD1,SAFB,SGK1,SH3BP2,ITSN1,FNDC3A,SLC9A5,KBTBD4,RCOR3,IFT122,KDM4B,WDTC1,SPATA7,CLASP2,LMF1,MPPE1,AAAS" Drug 1932_UP Metolazone [17560-51-9]; Up 200; 11uM; PC3; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BIN1,CDC42BPA,APLP1,ZBTB10,NCOA1,HIP1R,CDH2,CHRNB2,CST3,SNPH,RIMS3,GIT2,DDX46,SIDT2,EFNA3,SORBS3,ERBB2,ERCC2,FGF1,BAIAP2,DLL3,DENND2A,DISC1,GFER,GLYR1,PRRC2B,GPER1,PTOV1,MYL3,NME4,PALM,RAB3A,RGS3,SEC14L1,SLC1A3,CDK5RAP2,BEX1,WSCD1,KIAA0930,CABIN1,PLPPR2,NPDC1,FTSJ1,ITM2C,PCBP4" Drug 3128_DN Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABHD6,AP2A2,APAF1,APBB2,APC,SLC4A4,CDH8,CDH10,AKAP7,IQCK,ZNF337,B3GAT3,EXOG,DSCAM,ECM2,MRNIP,RASGRP2,TUBB4A,POMT1,GAB1,HNMT,MAP4,N6AMT1,NCAM1,NF1,SETD4,ST8SIA5,PLEC,CNTLN,ZFHX4,SH3BP2,ST6GAL1,SLC9A5,SLCO1A2,KDM4B,ZC3H13,IQSEC2,RAP1GAP2,DDN,ST5,ADGRL3,RBFOX2,CLIP2,MAP3K12,TIGD6" Drug 1270_UP Zoxazolamine [61-80-3]; Up 200; 23.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADORA3,CDC42BPA,KIF1A,SLC16A4,NEURL1,TPP1,COL9A2,IFFO1,CRY2,SIPA1L1,SLITRK5,DCAF8,SPATA2,SGSM2,DLG4,COQ7,INPP5K,ITGA7,MAP4,GIT1,P2RY1,PLCB2,PLTP,POU6F1,CNNM2,TMEM104,CNTLN,RAB3IL1,ZNF671,ITSN1,PEX26,SLC11A1,MYH15,ZSWIM8,EMC1,ADGRL3,TCF7L2,ATP13A2,ZNF34,TMOD1,PARD3,SPHK2,HPS4,UBE3B,NLRP3" Drug 7016_UP Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AK2,SEMA6A,SRPX,DOC2A,BIN1,CDC14B,RGS9,SCAPER,LDLRAD4,CA4,CAMK2B,LRRFIP1,PLEKHB1,TAOK2,NOS1AP,ZNF589,BAIAP2,SCARA3,C1orf61,GFER,ADAMTS13,GRIK5,SLC2A6,HLF,KCNJ9,VWA5A,MAP4,GIT1,NF1,PDE3B,LRP12,SAMD9,RIPOR1,RAB3IL1,SCN2B,RPH3A,PEG10,KAZN,WSCD1,KIAA0930,TPM1,VAV2,VIPR2,LMF1,WIPF1" Drug 408_UP sodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "RBM10,NDRG2,GAS7,ASPH,CADM3,RAB29,HAP1,SYNGR3,ARHGAP33,CHRM4,LHX2,DNAJB5,AATK,ARHGEF10,APPL1,DLG3,DRP2,EFNA3,SUGP2,EGFR,SRPK3,STX2,FGFR1,GPR19,PTPRT,LAMP2,NRGN,NTRK3,PMP22,SBF1,FERMT1,FNDC3A,SLC11A1,SOX10,DBNDD2,CLASP2,ITPRID2,MAPK8IP3,ANKRD28,BEX4,TRPC1,UBE3A,ZNF45,MPPE1,MVB12B" Drug 2289_DN Cloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASIC1,ADORA1,PPP4R4,ATM,CFLAR,SGCE,MAGI1,PLEKHB1,CNOT8,CNTN1,WHRN,GREB1,DSCAM,PLXNC1,ANKFY1,SORBS1,PDLIM5,ALDH1L1,SRCAP,GLS,CNTRL,IL6ST,KHK,ADAM22,ZNF862,NF1,NPR2,PDPK1,MAPK7,KCTD17,GSTCD,WLS,PPP1R9A,TSNAXIP1,ARHGEF9,EXOC7,ARHGEF12,PCDHA6,PCDHA5,SLC44A1,ZMYND8,LAT2,PHTF2,NUP214,JPH3" Drug 6941_UP 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ASPHD1,MRTFA,CFLAR,SYNJ2,MTMR2,ARHGEF1,PLEKHB1,WHRN,LRIG1,FEZ1,MICAL2,PDE4DIP,GNE,DTNA,FCF1,OPTN,EPB41L2,LRRC23,DLC1,FER,SEMA4D,PDLIM5,GAD1,GRB10,MEIS1,NFYA,CDK18,LRP12,RETREG2,FAM184A,RGS10,KCTD17,NEK11,NCBP3,MAPK12,SBF1,FERMT1,ZNF365,ZHX3,SPTAN1,SS18,EXOC7,TRIO,ZKSCAN5,VAV2" Drug 7247_DN Artemisinin [63968-64-9]; Down 200; 14.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "BIN1,PPFIA1,APP,ASPH,EPS15L1,NIPBL,CDC42BPB,PPP6R2,RCAN1,LPAR6,VPS13B,TUBB4A,DLC1,NBEA,POMT1,FAM49B,ATP2C1,DLL3,GART,GLUL,EML4,AGFG1,MPP2,ODF2,PDE1C,PDE4A,PPP3CC,SYTL2,CEP97,KIRREL1,GALNT10,HSPA4L,CCDC88A,SMARCC2,FNBP1,EMC1,FCHO1,TTBK2,KIAA0930,TCF7L2,TNS2,TRPC1,TRPM2,FIP1L1,MPPE1" Drug 4967_DN Cefaclor [70356-03-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AK2,BIN1,DGKD,APP,CFLAR,SYNJ2,GYG2,CA12,SCARB1,ASIC3,CLCN3,TPP1,QKI,AKAP7,SH2B1,DAPK3,GIT2,ARMCX2,MED12,TOM1,GLYR1,GRIK5,CACFD1,KCNN2,VWA5A,MATK,MSI1,NUMA1,MAPK7,RIPOR1,ATG16L1,RGS12,FBXW7,RASA3,PPP1R9A,ZCCHC24,UNC5B,SS18,MCF2L,CDK20,SSBP2,VAV1,WNK1,PRDM2,SSPN" Drug 1596_UP Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "NDRG3,ALAD,AMT,ARNTL,CDK13,ATM,ATP2B1,CFLAR,LDLRAD4,CLCN3,CTH,ZNF337,DBT,SIDT2,MBNL2,EIF5,OLIG2,RABEPK,DLC1,CAP2,EFCAB2,FYB1,VSIG4,TJAP1,MAP4,NELL2,ENPP2,PLCD1,MED1,PPP2R5C,MSANTD2,FAM192A,ATXN2,AMBRA1,BCAN,MAPKBP1,SPP1,EXOC7,EHBP1,SIRT1,TK2,VIPR2,WIPF1,ZNF23,RNF170" Drug 5920_DN rotenone; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "DOC2A,CDC14B,CDK13,PTCH2,BRINP2,CACNA1A,CACNA2D2,NRG2,CNTNAP2,SDC3,NOS1AP,AK5,DPH1,CDKL3,FGFR3,FOXG1,PRELID3A,GALC,GLYR1,GUCY1B1,KLF12,KCNMA1,MEF2C,MX1,NF1,NFYA,PDE4B,PLEC,PLXNB1,PPARA,RGS7,RGS12,SCN8A,ZFP30,DOCK10,FAIM2,TNIK,SPTAN1,VAMP1,ZEB1,TRIM2,HIF3A,VAV2,VGF,KCNAB1" Drug 5302_DN Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABHD6,CFLAR,SCARB1,ARHGEF2,PLEKHB1,PLAA,ENTPD4,CTH,PPP6R2,DLG3,DTNA,RBM12,CELSR3,EZH1,ANKFY1,GLS,CACFD1,INPP5B,MEIS1,NACA,NF1,NPR2,OGG1,PCDH9,PPP5C,PRPH,ELOVL2,ATG16L1,RGS10,RNASEL,ROBO1,FBXW7,FAM192A,FBXO11,SCMH1,EFHD1,SLC20A2,UNC5B,CDK19,TSPYL2,CLASP2,TRIO,ZKSCAN5,LMF1,TFIP11" Drug 3125_DN Nitrocaramiphen hydrochloride; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "NDRG3,FAM135A,MRTFA,PDE8B,KIF1A,ZFYVE9,NMT2,AKAP7,IQCK,SPOCK2,MAGI2,RABGAP1L,ECM2,FECH,CAMSAP1,ANKFY1,TRMO,INPP5K,RND1,GRM1,IL6ST,SMAD1,MAP4,NEK1,P2RY1,PLCD1,SLC25A23,BEND5,TMEM206,SEC14L1,ANKRD6,KDM4B,KDM4C,ARHGAP26,NCDN,PCDHGA10,KCTD2,TPM3,ZKSCAN5,PLPPR2,BEST1,LMF1,PARP11,ST7,TIGD6" Drug 2503_DN Suxibuzone [27470-51-5]; Down 200; 9.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABAT,SLC4A4,ADAM23,ADAM15,C5,MAP7,CSNK1E,DAPK3,CTIF,TRAPPC9,DPH1,DTNA,EIF5,ZNF589,GABRA2,ZNF44,INPP5K,MSL3,POLL,GNG3,IFI16,TJAP1,NNAT,OXTR,PLTP,LRRN3,PTK2,ZSCAN32,RAB3A,ZCWPW1,TRIM68,GALNT10,ZKSCAN3,WDTC1,BEX1,CLASP2,ATP11A,DMXL2,TNS2,FRYL,PIK3R5,RBFOX2,ZKSCAN5,LAT2,PRDM2" Drug 6822_DN Riboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AK2,EPB41L5,ATP6V0A1,BCL7A,GYG2,CAMK2B,FOXN3,TAOK2,RAB28,SH2B1,MFAP3L,DNM1,ING4,DENND4A,FHL1,CINP,DISC1,GLYR1,GPR19,NR3C1,GSN,ATXN2L,DHX35,HSD17B1,KCNH2,LSS,KITLG,NASP,NF1,NFYA,STRN3,MED1,PEX5,RAB3A,FAM192A,BTBD7,SNCA,SOX3,ASTN2,SEMA4A,PARD3,TRPC1,ZBTB14,EVI5,SMIM8" Drug 6672_DN Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ARID1A,APAF1,STX16,ST3GAL5,ARHGAP33,LHX2,DNAJB5,PICK1,AKAP7,WHRN,CREM,ABCG1,TENM4,SLITRK5,ARHGEF4,RABGAP1L,PLXNC1,EN2,SEMA4D,FYB1,TRAF3IP2,TXNL4A,LPAR4,GRM8,GUCY1B1,HLF,MAPT,NF1,PBX1,PC,PDE4D,PIK3R1,PPP5C,PTHLH,ARHGEF10L,GSTCD,ZNF821,MRAS,ASAP3,FHOD3,ST6GAL1,PPP4R3A,IQSEC2,BHLHB9,UGT8" Drug 2921_DN Cefalonium [5575-21-3]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ABAT,BRAP,OSBPL1A,CAMK2G,MAP7,KRIT1,ARHGEF1,SOCS6,TPP1,CLOCK,PPP1R16B,EDRF1,EXOG,DTNA,TSPAN5,ZNF589,ATP2C1,COPS8,RAB40B,IL11RA,MAP4,MX1,CNOT4,NUMA1,MINDY2,SNRK,ZCWPW1,ZNF671,TCP11L1,CLIP1,RXRA,TRAPPC13,TMEM156,ATXN1,PEX26,ZHX3,STX1A,KLHL7,TNS1,TPM1,SF1,MAP3K12,PRDM2,GDPD5,UBE3B" Drug 7454_DN Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "CDC42BPA,APAF1,PPFIA3,CDK5R1,ST3GAL5,CAMK2G,CTNND2,C2CD2L,DLG3,EXOG,DSCAM,EFNA3,SUGP2,TNK2,CD320,EFEMP1,BAIAP2,GPD2,HSF2,IDH3B,SCAMP5,NPR2,CCSER2,RETREG1,PPP3CC,PRODH,PTPRE,PEX5,RALGDS,MCMBP,FAM192A,AMBRA1,ZKSCAN3,MAPKBP1,KDM4C,ZBTB43,LHPP,ARHGEF9,TACC1,AHCYL2,PLPPR2,VAV1,VGF,REEP1,GDPD5" Drug 1244_UP haloperidol; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "AMT,APOC1,PPFIA3,ALDH7A1,BACH1,NRP2,CFAP410,CACNA1A,KRIT1,NEURL1,GPR37L1,TAOK2,CREB5,CRMP1,GPRASP1,SPOCK3,EIF5,ING4,MRNIP,CSPG5,TRAF3IP2,GAD1,NCKAP1,C1QL1,IFI16,PRKAR1B,WDR25,PTAFR,PTPRE,TMEM231,RAB3A,SH3TC2,C1orf54,GAL3ST4,TRAPPC13,RIMS1,RBM34,ZC3H13,MAPK8IP3,FAM168A,TBL1X,MGRN1,ZMYND8,NUP214,RNF170" Drug 2530_DN Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "NDRG2,ADRA1D,MRTFA,AMPD3,APC,MARK4,NCOA1,ADAM23,SYNJ2,MTMR3,CACNA1A,CDH10,PDE4DIP,DAPK3,RHOBTB1,SMG7,SPOCK3,EFNA3,TUBD1,VPS26C,FECH,CAMKK2,INPP5K,MSL3,PADI2,MAN1B1,ITGAM,MID1,NNAT,NLE1,LRP12,AMBRA1,FBXO11,KDM4B,KDM4C,KAZN,DMXL2,TCF7L2,ZEB1,ATP13A2,THRA,TMOD1,TRIO,MAP3K12,FAM13C" Drug 2564_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "DOC2A,TRMT9B,APAF1,CDC14B,MTMR3,LDLRAD4,SPAG9,TAOK2,FAM149A,ZNF337,GSDME,FCF1,CELSR3,ELN,PIPOX,DLC1,KHDRBS3,GAD2,MSL3,GNG3,MAP4,MEF2C,SCAMP5,N6AMT1,OCRL,CCSER2,KCTD15,NLE1,SYTL2,PTCH1,GALNT10,FNDC3A,CNKSR2,NUBPL,LIMS2,BTBD7,SLC20A2,SS18,TCF7L2,CDK20,UBTF,LMF1,XRCC4,REEP1,STMN4" Drug 6151_UP Azaperone [1649-18-9]; Up 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ALK,DOC2A,APBA2,APC,APOC1,CDK10,CACNA2D1,CBFA2T2,KCNAB3,CHRNA4,DNAJB5,SPOCK2,SGK2,OPTN,EFNA3,ING4,DMTN,ETV1,KAT8,FGFR1,AGAP2,GFRA1,PADI2,BACH2,SCIN,KPNA5,TAGLN3,TREM2,PBX1,GDAP1L1,FAM120C,ROM1,PRR5L,SLC30A10,SMTN,PKNOX2,FAIM2,SPTAN1,PLCB1,WWC1,CRTC1,HIF3A,TJP1,LMF1,VSNL1" Drug 4990_UP Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.55E-03 1.00E+00 3.32E-02 3.78E-01 45 199 "ADCY6,ADRA1D,TRMT9B,APC,ALDH7A1,CACNA1I,BAIAP3,NRG2,SPOCK2,DRD1,MBNL2,ELN,MTSS1L,NRN1,GPR153,ALDH1L1,GCNT2,SRCAP,GNAS,LPAR4,PCLO,SOX21,GUCY1A2,KCND3,LAMA2,AFDN,TAGLN3,MYO7A,MYT1,NELL2,MAPK7,KHDRBS2,NEK11,RPS6KA2,SCN2B,CNKSR2,PREX2,COLGALT2,PLCB1,ADGRL3,TBCEL,PCDHGA1,PARD3,NUP214,TIGD6" Drug ctd:D016912 Levonorgestrel CTD 6.59E-03 1.00E+00 3.34E-02 3.80E-01 48 215 "AGT,ADGRF5,PKP4,API5,AZGP1,PTBP2,FMNL3,CD86,DLGAP2,AHCTF1,CDC42BPB,GREB1,ZEB2,MRO,TMEM35A,F5,F8,NSG1,SARAF,GABRG2,RAPGEF6,GLYR1,ZNF638,FERMT2,NR3C1,ELOVL5,IGF1,IGSF1,MBNL1,PAK3,PDE1C,TMOD2,ABCB1,PPP2R2C,FAM182A,CPEB3,SLC2A5,BTBD3,SNRPN,FNBP1,DOK5,SYT11,KLHL4,NACC2,DDHD1,CSMD1,RFTN2,DOCK8" Drug 916_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.60E-03 1.00E+00 3.34E-02 3.80E-01 41 178 "CLK4,OSBPL1A,BIN1,CFLAR,MTMR7,CLU,DNAJB5,COL9A3,PDE4DIP,EDRF1,RCAN1,MBNL2,COQ7,CAP2,OGA,LPAR4,GRB10,DIDO1,CACFD1,ELOVL5,AFDN,NAP1L2,KLK6,C1orf54,MORC4,RPS6KA2,HSPA4L,SH3BGR,PPM1E,FNDC3A,SLC20A2,ZCCHC24,TSPYL2,JMJD6,RUNDC3B,TRPC3,ZMYND8,VLDLR,WIPF1,XRCC4,SEMA3B" Drug CID003032285 thiamylal Stitch 6.63E-03 1.00E+00 3.36E-02 3.82E-01 15 49 "CNTNAP2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,BCO1,PRKCB,PRKCG,PKN2,PRKCZ,MAPK3,SST,ABCC8" Drug CID000176407 Zm 241385 Stitch 6.63E-03 1.00E+00 3.36E-02 3.82E-01 15 49 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,ADRB2,ENTPD2,LRBA,GRM5,NTRK2,PRKACB,MAPK3,SLC1A2,SLC1A3,SLC6A1" Drug ctd:D003375 Coumestrol CTD 6.65E-03 1.00E+00 3.36E-02 3.83E-01 320 1796 "RALGAPA1,ABAT,ABCF1,ACLY,RBM10,C3orf14,FMNL2,ADD3,CDC7,KIAA1211,ESYT2,KIDINS220,AP1B1,MTUS1,KIAA1324,TAOK1,ALCAM,BCAR3,PCDH10,APBB2,EPB41L5,ALS2,APP,CDC14B,ARHGDIA,CDK13,ZBTB10,NCOA1,RASL11B,ALDH4A1,EIF4G3,ATP2B1,N4BP2L1,BARD1,BCS1L,DCAF5,BLM,CFLAR,BMP7,AP1M1,C5,RAB29,CA12,CAMK2D,VXN,CAST,CBR1,SCARB1,SYNGR3,ENTPD2,CDC27,DCLK1,MAGI1,CCPG1,CHN1,LHX2,EPS15L1,CLU,NMT2,FAM189A2,MAP4K4,IQCK,FAM171B,CDC42BPB,ENTPD4,ABCG1,LRIG1,CSNK1G3,SOCS5,FAM169A,PNPLA8,GREB1,CTNND1,CTNND2,DCAF4,PHF19,KIAA0513,CENPL,KIAA0586,DBN1,FBXL5,BLOC1S6,RHOBTB1,SACS,G3BP2,FAM107B,USP3,CPEB2,CASP8AP2,ABI1,PDCD6IP,DTNA,FARSB,ABCC5,DNM1L,E2F5,EDIL3,SNX29,EDN1,FCF1,RASGRP1,KLHL5,OPTN,EFNB3,PHF20L1,KMT5B,EGR3,TUBD1,EPB41L2,COQ7,ERBB2,ERBB4,MRPL37,SRARP,KATNAL1,CD320,SH3YL1,TAOK3,EFEMP1,CEP78,STRADA,FDFT1,PRMT5,OLFM1,POLR1B,FGFR1,TMEM164,MAD2L2,AMOTL2,FHL1,SEC23B,IP6K2,SYNCRIP,FOXM1,FOXO3,NBEA,TMEM107,SMC2,FAM49B,ATP2C1,CSPG5,OGA,ZNF44,AHCYL1,SYT17,SEPT9,GART,TUBGCP4,GFRA1,RUNDC3A,DBF4,GLS,RAB40B,FERMT2,PSRC1,GPD2,GPER1,NUDT21,GRB10,NR3C1,ZNF496,CIT,PSIP1,UBE2QL1,FRMD3,ARHGAP19,KLF12,ELOVL5,ACOT7,HMGB1,HSP90AA1,ICA1,USP54,IL6ST,ZNF678,ZNF385B,KIF5C,KTN1,L1CAM,STMN1,LIG4,SYTL4,NCOA7,MATN3,TM6SF1,MMP16,MXI1,MYO5A,MYO6,NASP,SFR1,NELL2,NRCAM,ODF2,OXTR,PBX1,PCDHGC3,PDGFRA,PIK3C2A,ANLN,SNX10,PKM,GPSM2,FAM216A,PMP22,STRN3,SH3KBP1,PPP2R5E,PPP3CC,PPP5C,PRKACB,MAPK3,SLC26A11,BCAS3,VPS13C,SLC22A23,SYTL2,ELOVL2,SPDL1,NKAIN1,TUG1,ACSS3,PLEKHB2,RBBP8,BSDC1,RET,ERI2,UBR7,MYH14,FAM161B,CLIP1,RMI1,FOXRED2,SAFB,ATXN1,IL17RB,GALNT10,TRA2B,HSPA4L,PPM1E,ARX,SHMT2,R3HDM2,SYBU,NBPF1,SEPHS1,SLC12A2,SLC12A4,ELMO2,EFHD1,BTBD7,COA1,CDK5RAP2,RCOR3,IFT122,TMCC1,FAM126B,TRERF1,SOX3,SPATA7,FNBP1,KDM3A,ZSWIM8,MYCBP2,NPAS3,SPART,TAB2,SEPT8,SULF2,GANAB,PRRC2C,SYNE2,DNAJC9,TMEM150C,COBL,TBL1X,SATB2,WASHC4,PSD3,OBSL1,DICER1,SIRT1,ITGB3BP,CBX5,TMPO,PARD3,RBFOX2,TPD52,TPM1,ELP5,PDSS1,RUNDC3B,TSN,TSC2,SSBP2,TUBB2A,SGK3,CADM1,RPRM,UBE2H,USP1,MEAF6,CCDC14,NSD2,RICTOR,SF1,ZIC1,LYPD6,ZBTB38,TMEM237,FTSJ1,PMEPA1,LRP8,EVI5,DOCK8,KAT6A,PHTF2,AAAS,FRMD6,NETO2" Drug CID000068615 AC1L2A3V Stitch 6.69E-03 1.00E+00 3.38E-02 3.85E-01 21 77 "ASIC2,ASIC1,ADCY2,ADCY5,ADCY6,ADCY8,PHF12,CCK,ASIC3,F3,PPP1R1B,AGFG1,MBP,AFDN,NPY,OPRL1,PCSK2,PDYN,PENK,SST,TAC1" Drug CID000447618 1 Ni Stitch 6.69E-03 1.00E+00 3.38E-02 3.85E-01 21 77 "AXIN2,BIN1,RGN,SUMF2,LRIG1,ARHGAP32,PPP1R1B,DKK3,GK,PTPN5,WIF1,HP,HPR,MAT2A,RAB3A,SLC12A4,SP2,AKTIP,TLR4,TMEFF2,KCNK12" Drug CID000000795 imidazole Stitch 6.71E-03 1.00E+00 3.40E-02 3.86E-01 53 242 "ADCY5,ADCY6,ADCY8,AGT,PDE8B,ALDH7A1,C5,CA4,CA12,NGB,GDA,BOC,CHRDL1,DTNB,FCF1,GPHN,GAD1,GAD2,GPD2,PTPN5,HBA1,HRH3,HNMT,HP,HPR,MAT2A,NOS1,NPPA,NPTX1,NPTX2,NUCB1,PC,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B,PKM,PMP2,FA2H,RNASE1,MAPK12,COPZ1,SP2,ADHFE1,SYNE1,TMPO,METTL3,SMUG1" Drug 7214_DN Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "KIDINS220,AP2A2,ALAD,EPB41L5,PPFIA3,CFLAR,CDK5R1,QKI,DZIP3,DBT,LYPD1,SUGP2,TNK2,STX2,VPS26C,KIAA1109,BAIAP2,SEMA4D,FAM49B,FYN,MSL3,PRRC2B,BTN2A1,ARHGAP19,INPP5B,MIA2,MPP2,NCAM2,PCDH9,CCSER2,PLEC,LRP12,PMS2,RIPOR1,FBXW7,SBF1,EPN2,SCMH1,FNBP1,KAZN,CABIN1,HIRA,LMF1,ZBTB14" Drug 4429_DN "ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "C1QTNF3,LTBP4,AMPD3,CDK10,ADGRB2,CFLAR,BMPR1B,CA8,CHM,NRXN3,CLU,TOX,DTNA,SIDT2,EGFR,ING4,LRRC23,ETV1,KIAA1109,FYN,DENND2A,HBS1L,ERAP1,FERMT2,SYNPO,SHISAL1,KHK,KIF2A,MEF2C,KITLG,MX1,ZNF862,PBX1,PLCB2,PMS2,RAD52,WDTC1,SPTAN1,SPTB,COLGALT2,SEMA4A,TMPO,ZNF24,PHTF2" Drug 1115_DN phenanthridinone; Down 200; 51.2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "SERPINA3,ADD3,KIDINS220,MTUS1,ALAD,BCAR3,EP400,ARRB2,MARK4,ZBTB10,CFLAR,SLC25A14,HOMER3,APPL1,ZFYVE16,DBT,SGSM2,PLEKHO1,SYNCRIP,GNAS,FERMT2,NUDT21,BTN2A1,KCNJ3,MKLN1,MMP16,MTR,CCSER2,RGS10,ROBO1,MCMBP,GALNT10,ITSN1,SHANK2,SLC15A2,TTC17,ZNF302,JMJD6,WWC1,TCF7,TCF7L2,KAT6B,UBE3A,ZIC1" Drug 6761_DN Chlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "BIN1,APLP1,APP,LGR5,CDK10,ASPH,CANX,CBFA2T2,CHM,QKI,CREB5,CTNND1,HP1BP3,SGSM2,EXOG,RCAN1,FCF1,SORBS3,CDKL3,FGFR1,ANKFY1,DISC1,ARFIP1,INPP5B,LIG4,LSS,CNOT4,OCRL,MINDY2,PPP5C,PRKAR1B,RGS10,FUZ,CCDC88A,ELMO2,SMARCD3,WDTC1,TAB2,CBX5,BEX4,VPS35L,KCNAB1,PHTF2,RNF146" Drug 2637_DN Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ADD1,EPB41L5,APP,KIF1A,CFLAR,CFAP410,SCARB1,SIPA1L1,PUM1,ARHGAP32,GIT2,LYPD1,DSCAM,IRAK4,F3,FER,FGFR1,AGAP2,ERAP1,MSL3,IL6ST,KCNJ3,IPO5,MAP4,LYRM9,PTPN13,RIPOR1,RAD52,SLC25A36,ZNF821,EPN2,ELMO2,MAPKBP1,ZHX3,SS18,ZNF34,TK2,TRPC1,WNK1,FIP1L1,MPPE1,C12orf4,SSPN,RNF146" Drug 1949_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; PC3; HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "PPFIA1,APBB2,GAS7,STX16,GYG2,CA12,KRIT1,INA,FEZ2,CTH,HDAC9,ZNF804A,DTNA,SGK2,YAF2,ACSL4,RACK1,FGFR1,PDLIM5,NCKAP1,TMEM8B,ARFIP1,CRCP,TJAP1,MPP2,MYL3,NFYA,CNOT4,NOVA1,NTRK3,PIK3CD,PLCD1,RAB3IL1,TCP11L1,ATXN2,ST6GAL1,SLC11A1,CDK19,EXOC7,PDLIM2,TCF4,NSD1,TMOD1,LAT2" Drug 1748_DN Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "NDRG3,OSBPL1A,C1QTNF1,SPOP,CAMK2B,PLAA,HINFP,ARHGEF10,ZNF337,MED12,ABI2,RASGRP2,SEMA4D,HTATSF1,MAN2A2,MAP4,MBD1,SCAMP5,AFF1,MYO9A,NEFH,NF1,NOS1,OPA1,RETREG1,RAB3IL1,MRPS18A,DGLUCY,SLC11A1,TSPYL2,POGZ,FCHO1,ANKRD12,TCF4,AHCYL2,TSN,HSPBP1,HIRA,VIPR2,LAT2,XRCC4,TRIM9,CIAPIN1,PDSS2" Drug 3689_DN PNU-0251126 [267429-19-6]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "APAF1,APBB1,ARNTL,BCL2L2,ST3GAL5,FUBP1,SCAPER,CBFA2T2,SCARB1,SYNGR3,CDC27,TAOK2,HOMER3,NCOR2,VCAN,SLITRK5,EDRF1,GIT2,DSCAM,DTNA,MRNIP,ETV1,FGFR1,POMT1,DLL3,FYN,GLI2,TDRKH,GPR17,PC,PCDH9,GPSM2,SPATA6,RAD52,TCP11L1,RCOR3,RBM34,CDK19,PBLD,SYT11,DNAH7,TRIO,LAT2,RNF146" Drug 1657_UP troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASPHD1,ABHD6,AK2,MRTFA,CDC42BPA,CFLAR,SOCS6,ENTPD4,CSNK1E,DLG3,RCAN1,TOM1,SIDT2,EFNB3,ANKMY1,ZNF589,BAIAP2,FAM49B,OGA,SYT17,ZNF276,GNG3,GRB10,IL6ST,PLCD1,STRN3,LRP12,PPP5C,PRODH,PTCH1,NEK11,ZNF821,WDTC1,ZCCHC24,ZNF423,IQSEC2,WSCD1,TNS2,ZKSCAN5,VAV2,VGF,EMSY,MPPE1,SENP7" Drug 6720_UP Paclitaxel [33069-62-4]; Up 200; 4.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "SLC12A5,PKP4,APAF1,APC,EIF4G3,BTRC,KRIT1,CHI3L2,EPS15L1,CNTFR,COL9A2,CRMP1,PHF14,CTH,DAPK1,MFAP3L,IGSF6,SCML2,EFCAB2,TACC2,GAD2,ERAP1,SRCAP,GPM6B,GPR22,INPP5B,KCNB1,VWA5A,TM6SF1,NOVA2,PTCH1,ELOVL2,ACSS3,RNASEL,RPE65,STUM,ZFP30,FBXO11,DZIP1,ACSBG1,COBL,DNAJC12,LAT2,NAV2" Drug 2739_DN Iopromide [73334-07-3]; Down 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "SLC12A5,MTUS1,MRTFA,APAF1,FAM131A,PPP4R4,HIP1R,CREM,CSF1,USP6NL,KIAA0753,E2F5,HIPK3,RRAGB,KAT8,CAMSAP1,PDLIM5,LILRA2,DIDO1,GRM7,PADI2,ATXN2L,ELOVL5,MAP4,NNAT,CNOT4,PLTP,POLG,PRKCZ,TMEM231,RAB3IL1,CEP97,TCP11L1,ZNF821,PREX2,SLC20A2,SMARCD3,TMCC1,NCDN,STX1A,TCF7L2,FLRT2,CLIP2,ZNF225" Drug 3570_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "AK2,AMPD3,ARRB1,PDE8B,MARK4,ASPH,CACNB2,HIP1R,SOCS6,ABI3BP,PDE4DIP,GIT2,TRAPPC9,DTNA,SUGP2,USP19,COPS8,HNMT,ICA1,LIG4,MAPT,ADAM22,NF1,NRCAM,SERPINE2,MBOAT7,PACSIN1,PTPRE,PEX5,EMID1,SH3BP2,NLGN1,SLC6A8,BTBD7,ZCCHC24,SPART,AJAP1,ARHGEF9,SIK3,ATP13A2,CABIN1,SMUG1,RUNDC3B,ZBTB14" Drug 5289_DN Flucytosine [2022-85-7]; Down 200; 31uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ADCY6,ZBTB10,NUMB,SLC4A4,ADAM15,BCL7A,CFLAR,SYNJ1,MTMR2,CREM,SH2B1,CTNND1,USP6NL,PHC2,PCOLCE2,GPR153,INPP5K,ZNF276,TCERG1,GOLGB1,GRB10,ARHGAP19,HSF2,INPP5B,KCNK1,MAN2A2,MAPT,PTOV1,OGDH,PLEC,MINDY2,PRKACB,ELMO2,EMC1,ZBTB43,SS18,FAM168A,MTCL1,TRIM2,NSD1,PARD3,WBP2,HIRA,DNAJC12" Drug 501_UP LY294002; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "SEMA6A,DGKD,APP,ASPH,RASL11B,SLC4A4,CADM3,RGS11,BMP7,ADGRG1,CNR1,RIMS2,GNE,ING4,TNK2,FGFR1,BAIAP2,FLNC,GABRA4,GLS,STON1,NPR2,OMG,PDE4D,CCSER2,ZFYVE21,PLEC,MBOAT7,DPF2,KLHL11,RNASEL,SYNDIG1,SH3BP2,SH3GL3,KIF16B,SLC9A5,EFHD1,MAPKBP1,EMC1,MYCBP2,ZC3H13,ZKSCAN5,UCHL1,MPPE1" Drug 2711_DN Isoetharine mesylate salt [7279-75-6]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASIC1,SLC12A5,DOC2A,ANK3,CDK10,KIF1A,FUBP1,LDLRAD4,EPS15L1,CLCN4,HOMER3,IQCK,SLC4A7,NRG2,USP6NL,HDAC9,SMG7,DTNA,RBM12,CELSR3,RASGRP2,NCALD,FHL1,NBEA,KHDRBS3,ALDH1L1,ZNF276,GPM6B,SLC2A6,IFI16,MAP4,SLC25A23,RAB3IL1,RET,TCP11L1,FOXRED2,SH3BP2,NUBPL,SLC11A1,COLGALT2,KAZN,ADGRL3,TCF7L2,LAMP5" Drug 7044_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "CDK10,CFAP410,CACNA1D,CACNA2D2,QKI,HOMER3,NCOR1,ARHGEF10,PDE4DIP,RIMS2,DGKG,DAPK3,HP1BP3,NR1D2,EFNA3,EFCAB2,RND1,POLL,NR3C1,ELOVL5,HNMT,KIF5C,MBNL1,SMIM7,PTK2,RAD51D,ZDHHC14,SBF1,DHX30,SLC11A1,SHANK2,SLC22A4,TNIK,IQSEC2,POGZ,VAMP1,MCF2L,IQCE,KIAA0930,PSD3,TNS2,FLRT2,ZNF45,SMIM8" Drug 3507_UP Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ALK,SYT13,FAM131A,PLA2G4C,DNAH17,CHRD,CACNB4,RUNX1T1,ARHGEF2,CDH2,ATN1,EDN3,TENM1,DCTN2,FYB1,SEPT9,ALDH1L1,RND1,GRB10,SYNPO,ITIH2,ADAM22,ZNF862,NEUROD1,NTRK2,PACSIN1,MINDY2,MAPK7,SNRK,PTX3,RAB3IL1,SLC6A15,KLHDC8A,NLGN1,SOX10,SP2,THSD1,EPB41L3,TBCEL,TNS2,TEX15,TK2,TNS1,VIPR2" Drug 6072_DN Etanidazole [22668-01-5]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "AP2A2,FAM131A,MARK4,ATP6V0A1,CACNA1I,BTRC,CFAP410,NEURL1,ARHGEF2,RCHY1,NECTIN3,SIPA1L1,SDC3,RIMS2,DTNA,EDNRA,C3orf18,LRRC23,KIAA1109,C1orf61,CGREF1,DISC1,SEPT9,INPP5K,POLL,INPP1,VWA5A,MID1,NF1,NUMA1,PTK2,RIPOR1,ZDHHC14,SEC14L1,FAM214B,SNCA,IQSEC2,TSPYL2,PHLDB1,SYN2,PCDHA5,SLC44A1,TMOD1,ZNF45" Drug 3841_DN Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ADRA1D,APC,APP,CDK10,NUMB,ALDH4A1,ADAM15,ARHGEF7,CBFA2T2,FOXN3,SOCS6,CHM,CLCN3,HOMER3,EDRF1,DAPK3,DTNA,HIPK3,MBNL2,EIF4G1,PLEKHA1,KIAA1109,PDLIM5,GAB1,GLYR1,HTATSF1,MAP4K5,KCNF1,LSS,ZNF862,NEK1,RETREG1,PLCD1,SH3BP2,IQSEC2,ST5,PLCB1,EXOC7,TBL1X,CABIN1,FAM155A,REEP1,SNX27,PHTF2" Drug 942_UP prazosin hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ST3GAL5,SYNJ2,BTRC,CAMK2G,HIP1R,DCLK1,LRRFIP1,SH2B1,CRY2,GREB1,DCAF4,DBT,KBTBD11,TRAPPC9,OPTN,ACSL4,SCML2,ZNF589,OGA,POLL,ATXN2L,HMGCR,LMO2,LSS,MIA2,NPTX1,PIK3CD,PRKAB2,RAB3A,RAD52,ZDHHC14,TCP11L1,PAQR6,RYR1,SLC6A8,SHANK2,TROVE2,THSD1,PHLDB1,EXOC7,KCTD2,LMF1,WNK1,MAP3K12" Drug 6779_DN Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ADRA1D,AP2A2,APC,PLA2G4C,SLC4A4,CBFA2T2,CSF1R,ARHGEF10,PDE4DIP,SDC3,EDRF1,TRAPPC9,RCAN1,ELAVL3,ANKMY1,ZNF589,PRELID3A,MALT1,GLS,GRB10,NR3C1,ATXN2L,MDM4,MPP2,NNAT,PDE3B,PPP5C,PRKAR1B,TMEM104,ZNF821,ZFP30,FBXO11,FNDC3A,SHANK2,RBM34,TROVE2,PLCB1,ATP11A,SEMA4A,TRIM2,TNS2,AHCYL2,LMF1,GDPD5" Drug 334_UP 6-mercaptopurine monohydrate; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASIC1,NDRG2,CACNA1I,CAMK2A,CDH2,SLIT2,NMT2,NIPBL,IFFO1,AATK,DCC,DLG3,ABCC9,USH1C,SUGP2,EPHB1,SPEG,DPYSL4,TRMO,ATP8A2,SRCAP,SESN1,COPS8,GNAO1,ELOVL5,KIF5A,NOS1,SLC11A2,SETD4,PLCD1,PPP2R2B,PTPRD,GSTCD,ZNF821,SH3GL3,FRMPD1,FAM214B,PKNOX2,SLC8A1,NXT2,AHCYL2,PLPPR2,XRCC4,MPPE1" Drug 6076_DN Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "APBA2,PPFIA3,CBFA2T2,CNOT8,HOMER3,CNTN1,CRY2,EDRF1,MAML1,ARMCX2,DMPK,DTNA,MBNL2,ING4,STX2,ANKMY1,IQCG,FAM49B,SEPT9,GCNT2,GNAS,GRB10,CACFD1,KCNF1,LMO2,MAP4,TM6SF1,MID1,LYRM9,NF1,PRPH,FAM184A,RGS10,SYBU,SLC6A8,WDTC1,UNC5B,THSD1,FCHO1,MAPK8IP3,PLCB1,PARD3,VGF,ZNF45" Drug 5491_DN Pizotifen malate [5189-11-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASPHD1,ABHD6,AP2A2,MTUS1,C1QTNF3,APBB2,APC,ALDH4A1,CFLAR,ST3GAL5,KRIT1,TAOK2,RAB28,ZFYVE9,HOMER3,AKAP7,PARD6A,SIDT2,RBM12,DLC1,FHL1,DPYSL4,GNG4,ARHGAP19,ITPKB,JAK2,MPP2,OGDH,PDE4B,PRODH,NKAIN1,GTDC1,RGS3,FOXRED2,SMTN,SCMH1,MCF2L,TK2,UBE3A,PLPPR2,VGF,PRDM2,HPS4,PCBP4" Drug 3481_UP Iopromide [73334-07-3]; Up 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "AMPD3,ARHGDIG,CDK13,RASL11B,ATM,CFLAR,CACNA1D,ARHGEF2,SLC4A7,ENTPD4,GREB1,TBC1D5,HP1BP3,EGFR,EGR3,PLEKHA1,C3orf18,VPS26C,PDLIM5,ERAP1,RND1,NR3C1,IL6ST,JAK2,KCNH2,KHK,MAP4,TM6SF1,PDE3B,PMS2,MINDY2,PRKAR1B,SUPT20H,PPP1R9A,SMTN,FAM214B,TMCC1,TROVE2,PSD3,HEY2,TRIO,ZNF24,REEP1,SSPN" Drug 4960_DN Miconazole [22916-47-8]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "APP,CDK13,CFLAR,KRIT1,LHX2,QKI,AKAP12,SOCS5,PDE4DIP,JAKMIP2,HP1BP3,C2CD2L,MAMLD1,EFNA3,SUGP2,SORBS3,GALC,MALT1,COPS8,KIF5C,NASP,NFYA,CNOT4,SLC11A2,ODF2,OGDH,PDE3B,RETREG1,PLCD1,FBXW7,LGR4,ATXN7,ANKRD6,SMTN,BTBD7,ELOVL4,STX1A,FAM168A,EXOC7,TRIO,SSBP2,REEP1,ZNF189,PRDM2" Drug 1001_UP Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASIC1,PPFIA3,ALDH7A1,CFLAR,ST3GAL5,REPS2,PDE4DIP,NOS1AP,GPRASP1,TOM1,EFNB3,ING4,DMTN,F8,IQCG,FAM49B,HBS1L,ERAP1,TMEM8B,SESN1,POLL,GPR37,CNTRL,LSS,MIA2,ADAM22,LYRM9,ZNF862,MINDY2,MAPK8,PRPH,RALGDS,FAM184A,CARF,GSTCD,TRAPPC13,SLC15A2,KDM4C,EXOC7,SZT2,NR2C2,ZMYND8,SSPN,SENP7" Drug 5544_DN Prednicarbate [73771-04-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "APOC1,ATM,CFLAR,CDK5R1,DCAF8,GIT2,DLG3,ING4,PLEKHO1,SEPT9,INPP5K,NR3C1,RNFT2,SLC2A6,ARHGAP19,IL6ST,KCNJ3,NAP1L1,NEK1,NF1,PDE3B,PTPN13,RAD51D,GTDC1,FBXW7,SBF1,NUBPL,PPP4R3A,EPN2,ZNF430,SLC22A4,RCOR3,RBM34,USP33,EMC1,ZBTB43,SPART,NXT2,ASTN2,TACC1,TCF7L2,PARD3,MPPE1,KAT6A" Drug 7036_DN Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "NDRG2,BRAP,AP2A2,CDC42BPA,BCAS1,ALDH4A1,EIF4G3,BCL7A,CFLAR,CDH10,LHX2,RAB28,IQCK,NCOR1,LYPD1,PARD6A,CDON,EFNA3,COQ7,ANKMY1,FOXG1,DISC1,POLL,TDRKH,EML4,LIG4,MITF,PLXNB1,STRN3,PTK2,RPS6KA2,SUPT20H,SH3BP2,FERMT1,EPN2,ZHX3,IQSEC2,SPART,CEP68,JMJD6,TMEM121,KCTD2,RPRM,TIGD6" Drug 6068_DN Estropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ALCAM,PDE8B,DNAH17,ATP6V0A1,ADAM23,MTMR3,GYG2,BTRC,NEURL1,SOCS6,CLU,GREB1,RIMS2,RIMS3,MFAP3L,ATN1,TOM1,ING4,STX2,FGF12,GAB1,INPP5K,GLS,GRM1,SLC2A6,DHX35,IPO5,MAP4,KITLG,PCDH9,PDE4B,PRKAR1B,MAPK8,RAB3IL1,ZDHHC14,RGS3,SEMA6D,KIF13A,ZCCHC24,EMC1,PHLDB1,PLPPR2,VLDLR,ZBTB14" Drug 1864_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "NDRG2,KCNAB2,APBB2,ARNTL,ZBTB10,MTMR9,SPAG9,IQCK,CREM,PPP1R16B,DAPK1,RCAN1,DTNA,MBNL2,EIF5,ING4,COQ7,CAP2,AGAP2,ANKFY1,POMT1,GPR19,BTN2A1,ICA1,TJAP1,LSS,MITF,OCRL,CCSER2,PPP3CC,MAPK3,CCDC88A,BTBD7,TMCC1,KDM4C,IQSEC2,RGL1,ARHGEF9,CAMSAP2,KIAA1107,SZT2,NSD1,PIK3R5,ZNF32" Drug 1730_DN Ethamivan [304-84-7]; Down 200; 18uM; HL60; HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "RBM10,ADD3,PLA2G6,MRTFA,ATP2B1,CFLAR,MTMR3,CANX,CAST,CD86,PREPL,NCOR1,RUBCN,ZNF337,FBXL5,TRAPPC9,ABI1,PHF20L1,ENO2,DENND4A,ZNF589,KIAA1109,ATP2C1,PRRC2B,KTN1,LAMP2,MBD1,SETD4,SMIM7,LRP12,PTPA,PPP2R5C,PTK2,ARID4A,BSDC1,CHD9,FBXO11,POGZ,SS18,STAU1,TACC1,AHCYL2,VIPR2,ST7" Drug 2780_UP Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ACTN2,ARID1A,APBA2,APC,APLP1,APOC1,ARHGDIG,MARK4,CACNA1I,ARHGAP33,LHX2,FADS2,KBTBD11,TOM1,FGF12,C1orf61,DPYSL4,GNAL,SLC2A6,IL6R,KCNMA1,MAPT,PTOV1,NRGN,PLCD1,MTRF1L,CEP41,PTHLH,KCTD17,RPS6KA2,STUM,ASAP3,SLN,KDM4B,WDTC1,PEG10,OBSL1,TEX15,CHST8,THBS4,TK2,HIRA,EMSY,SLC17A7" Drug 2295_DN Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "ASPHD1,PPFIA3,ARHGEF1,TPP1,DNAJB5,BAG4,FAM169A,DZIP3,GIT2,HP1BP3,LYPD1,IRAK4,ING4,COQ7,F8,WAC,ACSL4,ZNF589,TRMO,GNG4,KCNJ3,KIF5C,MBD1,MPP2,ZNF862,NFYA,SLC11A2,PPP5C,FERMT1,FBXO11,ZNF365,PPP4R3A,KBTBD4,BTBD7,SEMA4A,PCDHA6,TMPO,BEX4,HIRA,CLDND1,EMSY,GDPD5,UBE3B,SSPN" Drug 6124_DN Cyproterone acetate [427-51-0]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 6.74E-03 1.00E+00 3.40E-02 3.86E-01 44 194 "MTUS1,MRTFA,BIN1,ATP6V0A1,CAPN3,AP4M1,ARHGAP33,CTIF,DBN1,MRNIP,COQ7,ST3GAL6,GABRA4,SEPT9,ALDH1L1,TXNL4A,CRCP,GLYR1,MSL3,GPR22,MAP4,CCSER2,SMOX,SLC25A23,PILRA,PRKCZ,ZSCAN32,PEX5,RIPOR1,PID1,RET,RGS10,MAP6D1,PAQR6,FOXRED2,SEC14L1,SH3BP2,ATP11A,PJA1,DNMBP,TCF7L2,ZNF34,FLRT2,NSD2" Drug ctd:D013974 Thyroxine CTD 6.74E-03 1.00E+00 3.40E-02 3.87E-01 35 147 "CDC7,ADORA1,AGT,AMH,APP,TMEFF1,BMP7,CACNA1D,CALB1,INA,SULT4A1,CNTN1,NCOR1,NCOR2,CS,CSNK1E,FGF1,GAP43,GLUL,GPD2,NR3C1,HMGB1,IGF1,HES5,KCNA4,KCND2,KCND3,NPR2,PCSK2,POU3F4,MAPK3,EPC1,SIRT1,THRA,ZIC2" Drug CID000004752 NSC 523214 Stitch 6.74E-03 1.00E+00 3.40E-02 3.87E-01 35 147 "MYH7B,SPTBN4,CALM1,CDC42,CDH2,CFL2,FHL5,SV2A,TUBD1,PTK2B,TUBB4A,ACTL6B,TUBA8,GSN,SCIN,TUBB2B,CTNNA3,SLCO1C1,TMOD2,PSMA6,GDPD2,PTK2,FNDC3A,SPTAN1,SYP,TJP1,ACTR6,TMOD1,TNNT1,TPM1,TPM2,TPM3,TPM4,TUBB2A,TUBB1" Drug CID000004217 ML-9 Stitch 6.74E-03 1.00E+00 3.40E-02 3.87E-01 35 147 "MYH7B,ALDH7A1,CALM1,CAMK2B,CAMK2D,KRIT1,CDC42,MYL6B,DAPK3,DYRK1A,EDN1,EPB41,FGF1,ACTL6B,GSN,MYLK2,IGF1,KCNC1,KCND2,KCND3,MYL3,NPY,PDE3B,PIK3C2A,PIK3CD,PIK3R1,PKM,PTPA,PRKCB,PRKCG,PTPN13,SLC12A2,MLC1,ACTR6,PCDH15" Drug 5950_DN "trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 6.76E-03 1.00E+00 3.41E-02 3.88E-01 40 173 "ABR,ARID1A,BCAR3,BCL7A,CFLAR,AP4M1,SOCS6,SMARCAL1,CHD1L,FAM169A,ZNF804A,DLG3,DYRK1A,TRAF3IP2,GART,GBX2,GCNT2,GPER1,GUCY1A1,HAS2,MX1,PDE1C,PTHLH,SH3TC2,SAFB,TRA2B,SCAF8,URGCP,KBTBD4,TMCC1,ZC3H4,NSD1,CRTC1,NACC2,KAT6B,UBTF,ZBTB14,ZNF24,PRDM10,MPPE1" Drug CID000000346 p-arbutin Stitch 6.79E-03 1.00E+00 3.42E-02 3.89E-01 47 210 "KLRC4,KLHL13,CPNE5,BMPR1B,AIFM1,LRBA,TMEM59L,IGDCC3,FRMPD4,DCT,DDX46,DPYSL2,CACNG7,VPS13B,EPS8,NCALD,EFS,FAM49B,BRSK1,GALC,C15orf41,GPD2,B4GALNT4,GPR26,BTN2A1,GUCY1A2,MAP4K5,PACSIN2,HPSE2,NEGR1,NKD1,IL6ST,GPR155,RASGEF1B,PSMD13,KCTD17,LRRTM4,FBXO11,RAB3GAP1,ERC1,LRRC4,NEU4,TCF12,DNAH7,TSC1,PRR18,PITPNB" Drug CID000447988 AC1L9LGY Stitch 6.89E-03 1.00E+00 3.47E-02 3.95E-01 22 82 "BSN,NOG,CSF1,CSF1R,OLIG2,FGF1,GFRA1,KITLG,MYO7A,NCAM1,NEUROD1,NTRK2,NTRK3,PDGFRA,PRPH,RET,ZDHHC4,RLBP1,RPE65,SOX1,SOX2,TJP1" Drug CID000198238 R 111 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "RGN,CHRM1,TAC1,TAC3,RASD2" Drug CID000196373 gamme Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CACNA2D2,DLL3,PDCD2,ABCC8,HPS4" Drug CID006439268 lactosyl lysosphingolipid Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "EGFR,GALC,RYR1,RYR3,NETO1" Drug CID000076113 TMBs Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "BCHE,BOC,F3,SAFB,SALL1" Drug CID000104952 Dcstx-saxitoxin Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "SLC25A18,NKX6-2,CIT,NEUROD1,ST8SIA2" Drug ctd:D015853 Cysteine Proteinase Inhibitors CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ANXA7,CLU,PLPPR4,PLPPR1,PLPPR5" Drug CID000065203 rhodamine 110 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "TPP1,ABCB1,SELL,SIRT2,SIRT1" Drug ctd:D002186 Cannabinoids CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CALM1,CAMK2B,SCARB1,FDFT1,SEMA3B" Drug CID005486761 K00271 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "BLM,MYT1,PCMTD2,NSD1,TEK" Drug CID000133806 IS-Gal Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "POLL,CIT,PMS2,SELL,TF" Drug CID000123864 Tyr(3)-sms Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CHGA,MCHR1,SST,SSTR1,SSTR2" Drug CID003081782 KS-505a Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ALDH7A1,CALM1,KRIT1,GPR162,PDE1C" Drug ctd:D018691 Excitatory Amino Acid Antagonists CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CHRNA4,CHRNB2,GFAP,GRIK1,NEFM" Drug ctd:C023990 tiotidine CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "GABRA1,GABRA2,GABRA3,GABRG1,GABRG2" Drug CID000016180 amino-L Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "BCHE,HDAC9,PDLIM5,GSN,SAFB" Drug CID000445281 X Bb Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "MCHR1,FOXRED1,SST,SSTR1,SSTR2" Drug CID000012463 tetrachlorobenzene Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CBR1,CBS,APPL1,DCT,STAG2" Drug CID000054765 bambuterol Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ACHE,ADRB2,BCHE,PRIMA1,SALL1" Drug CID004198643 c219 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ABCG2,ERBB2,ABCB1,GSTCD,RXRG" Drug CID000208925 ONO-2506 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "FOLH1,GFAP,S100B,SLC1A2,SLC1A3" Drug CID000014385 "3,3',4',5-tetrachlorosalicylanilide" Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CD86,CLTC,PAX6,SALL1,RGMA" Drug CID000004141 methylfurmethide Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ACHE,BCHE,CACNA1A,CHRM1,GNAS" Drug CID000516788 ferrous oxalate dihydrate Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "LGI1,F8,FECH,DNER,OPA1" Drug CID006439414 PD 136450 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "APOC2,CCK,CCKBR,CHGA,SST" Drug CID009898619 Depreotide Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "MCHR1,SST,SSTR1,SSTR2,SMUG1" Drug ctd:C000603500 4'-methoxy-1-naphthylfenoterol CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ABCG2,ABCC5,EGFR,ABCB1,PKM" Drug CID000163663 SP-Gly Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CCK,B3GAT1,TAC1,TAC3,TACR1" Drug CID000096177 "2,4-diamino-6-nitrotoluene" Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "DYNLL1,GMPR2,MX1,RDX,TNNT1" Drug CID004359312 NS3763 Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "DLG4,GRIK1,GRIK4,GRIK5,GRM5" Drug ctd:C047721 artemisic acid CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "DCT,HMGCR,KIT,KITLG,MITF" Drug CID000065872 eptastigmine Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ACHE,BCHE,CHRM1,DMTN,SPP1" Drug DB01942 Formic Acid Drug Bank 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CASK,GPHN,FGF1,NOS1,RNASE1" Drug ctd:D000249 Adenosine Monophosphate CTD 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "PPARGC1A,PYGM,NUDT11,SLN,NUDT10" Drug CID000001708 Fd I Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "AMT,SIRPA,NPTX2,SALL1,WDTC1" Drug CID000012585 2-pentene Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "ABAT,CBS,NBL1,SP2,SYNE1" Drug CID000098494 benzo(F)quinoxaline Stitch 6.92E-03 1.00E+00 3.47E-02 3.95E-01 5 9 "CHRM1,GRIK1,GRIK3,GRIK4,GRIK5" Drug 4405_UP Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-03 1.00E+00 3.47E-02 3.95E-01 43 189 "ASIC2,NDRG2,ANK3,PPP4R4,CCDC181,N4BP2L1,CHM,TAOK2,SNCAIP,C2CD2L,RCAN1,HIPK3,MBNL2,TNK2,C3orf18,IGSF6,CEND1,CORO2B,FHL1,SEMA4D,FYN,RND1,EML4,SYNPO,KCND3,MDM4,AFDN,BCO1,GPR85,LRRN3,PTCH1,RPS6KA2,PPM1E,CPEB3,PPP4R3A,ARC,SYP,SYT5,KIAA1107,HEY2,VIPR2,LAT2,MVB12B" Drug 882_UP ionomycin calcium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 6.92E-03 1.00E+00 3.47E-02 3.95E-01 43 189 "SERPINA3,SEMA6A,PPP4R4,ST3GAL5,LDLRAD4,CHRNA4,DNAJB5,COL9A3,ABI3BP,NRG2,SNCAIP,CX3CR1,NTM,RCAN1,ABCC9,USH1C,PLXNC1,EPB41,SIGLEC8,GLS,LPAR4,GRM1,FICD,GPR45,HNMT,KCND3,AFDN,MSI1,NUMA1,PLTP,SEPT4,RASGRF1,SLA,ZNF365,TSPYL2,CAMTA2,VAMP1,SYT5,TRIM2,CHST8,KCNK12,NUP214,NLRP3" Drug 7002_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 6.92E-03 1.00E+00 3.47E-02 3.95E-01 43 189 "SLC12A5,ANK3,CFLAR,SCAPER,BTRC,ARHGEF1,FOXN3,PLEKHB1,SLIT2,HOMER3,BRINP1,SGSM2,MED12,ING4,ZNF589,FECH,GPR153,ALDH1L1,SESN1,STON1,IGSF1,INPP5B,IPO5,SMAD1,MAP4,MAPT,NF1,PRKAR1B,MAPK8,PTPRE,ZNF821,SLC1A7,ZKSCAN3,ZCCHC24,IQSEC2,MAPK8IP3,ELOVL4,TRIM2,TNS2,CDK20,LMF1,ZNF45,SSPN" Drug CID006857724 platensimycin Stitch 6.93E-03 1.00E+00 3.47E-02 3.95E-01 18 63 "CNTFR,OLIG2,IGSF6,FGFR3,GFAP,GFER,RND1,IL6ST,LIFR,NKX2-2,PDGFRA,SERPINI1,PIK3C2A,PIK3CD,PIK3R1,CLIP1,ZFP91,PIK3R5" Drug ctd:D013096 Spermine CTD 6.93E-03 1.00E+00 3.47E-02 3.95E-01 18 63 "ASIC1,ACTN2,ADRB2,MYOM2,DMD,BVES,MAP4,MEF2C,MYH3,NFE2L2,NPPA,SMOX,MAPK8,RYR1,SCN8A,COBL,TNNT1,TPM2" Drug CID000002104 AC1L1CXF Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "PRX,CAMK2B,CAMK2D,HDAC4,HEPH,DRD1,PPP1R1B,HTR2A,NOS1,TROVE2,SYN1,SYN2" Drug CID000003225 endothall Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "CAMK2B,CAMK2D,EDNRA,INPP5K,PPM1L,PPP2R2C,PTPA,PPP2R5E,PPP3CA,PPP3CC,PPP2R3C,CABIN1" Drug CID000002494 AC1L1DSZ Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "ADCY2,ADCY5,ADCY6,ADCY8,SIRPA,DRD1,NPY,OPRL1,PENK,SLC8A2,SLC8A1,TPM3" Drug CID005289334 Sb-H Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "CDK5R1,RHBDL1,PRC1,GDA,FKTN,PKD1,RYR1,SLC6A7,TSC1,TSC2,MSRB3,GAN" Drug CID000123694 Ap6A Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "ADORA1,ADORA2A,ADORA3,P2RX6,LPAR6,LPAR4,P2RY13,P2RX7,P2RY1,NUDT11,NUDT10,P2RY12" Drug CID000001649 3-bromo-7-nitroindazole Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "ADORA1,ADORA2A,ADORA3,DRD1,GRIK5,GRIN2C,GRIN2D,GRM7,KCNJ3,NOS1,PTPRD,RNASE1" Drug CID000009688 phenylquinone Stitch 6.96E-03 1.00E+00 3.49E-02 3.97E-01 12 36 "CHRDL1,EDNRB,ELAVL3,HRH3,HNMT,OPRL1,PENK,GLDN,SPP1,SYNE1,TRH,NTSR2" Drug CID000130952 AWD 122-14 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ALDH7A1,CACNA2D1,PDE3A,PDE3B" Drug CID000195814 Ranatachykinin A Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "B3GAT1,TAC1,TAC3,TACR1" Drug CID000048229 talniflumate Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADORA2A,CLCN3,PDE4B,PDE4D" Drug DB00679 Thioridazine Drug Bank 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADRA1B,DRD1,HTR2A,KCNH2" Drug CID000111148 AR45 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "BCHE,HMGCR,KCNH2,MAPK3" Drug CID006914597 2cmo Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GRIA1,GRIA2,GRIA4,GRM3" Drug CID000122475 B-31 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CREM,EGFR,ERBB2,FCGRT" Drug CID000078910 NSC692750 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "FCGRT,GFAP,RYR1,RYR3" Drug CID003084961 oroxindin Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ARHGDIA,DLG4,CIT,NOS1" Drug DB00806 Pentoxifylline Drug Bank 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADORA1,ADORA2A,PDE4A,PDE4B" Drug CID000100657 diphenyl ditelluride Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ALAD,GFAP,NEFM,NEFH" Drug CID000002527 AC1Q5P7C Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ABAT,MED12,MAG,TRH" Drug CID000360780 NSC623156 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "AMPD2,AMPD3,PNMA2,POLG" Drug CID000040461 isoarecoline Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ACHE,BCHE,CHRM1,CCDC88A" Drug CID002816385 In2-7 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "COL9A1,COL9A2,COL9A3,MATN3" Drug CID000019094 lora Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "TBPL1,BOC,AASS,MAT2A" Drug CID003396482 AC1MQ5W8 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ACHE,CACNA1I,PAX6,SLC12A2" Drug CID000008906 lauryl methacrylate Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CCK,CCKBR,F8,PLP1" Drug CID006304902 SIB-1757 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GRM1,GRM2,GRM5,GRM8" Drug CID005490350 6-amidino-2-naphthol Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ASIC2,ASIC1,AMH,ASIC3" Drug CID000190809 CGS 27830 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug CID006328526 AC1O3HA7 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "MCHR1,SST,SSTR1,SSTR2" Drug CID000124318 choline mustard aziridinium Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ACHE,BSN,CHM,GAD2" Drug CID000214788 Ro 44 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CNTN1,ELN,F3,RBFOX2" Drug CID000124656 3-acetylisoquinoline Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GRIK1,GRIK3,GRIK4,GRIK5" Drug ctd:C411827 "2,5-dihydro-2,4,5-trimethylthiazoline" CTD 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CACNA2D1,CCK,GAD1,PENK" Drug CID009794218 MTEP Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GRM1,GRM2,GRM5,GRM8" Drug CID006367228 beidellite Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "BLM,F5,DNER,CLSTN2" Drug CID002733524 AC1MBZ3L Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GRM1,GRM2,GRM5,GRM8" Drug CID000131450 SHA 91 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADORA1,ADORA2A,ADORA3,MATN3" Drug CID000065874 saterinone Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ALDH7A1,PDE3A,PDE3B,ENPP2" Drug CID000134928 4-methylumbelliferyl phenylphosphonate Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "PCSK1,PDE4B,PDE4D,ENPP2" Drug DB00761 Potassium Chloride Drug Bank 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "SLC12A5,SLC12A6,SLC12A2,SLC12A4" Drug CID002782538 t180 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ITGAM,MATN3,SELL,ABCC8" Drug CID000131433 SHA 118 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADORA1,ADORA2A,ADORA3,MATN3" Drug CID000196897 Bq 153 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000192432 Urechistachykinin I Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "B3GAT1,TAC1,TAC3,TACR1" Drug CID000002149 GABOB Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ABAT,MED12,CIT,EPM2A" Drug CID000188913 RU-43044 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "NR3C1,PTPN5,HP,HPR" Drug CID000154889 4-hydroxy-1-phenyl-1-pentanone Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GFER,PTPN5,HP,HPR" Drug DB01544 Flunitrazepam Drug Bank 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GABRA2,GABRA3,GABRA4,GABRA5" Drug CID000154561 7-hydroxy-1-phenyl-1-octanone Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GFER,PTPN5,HP,HPR" Drug CID005311469 TAK-044 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "AGT,EDN1,EDN3,EDNRA" Drug CID000012008 chloro-m-cresol Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CACNA2D1,QDPR,RYR1,RYR3" Drug CID000209654 Sv 2 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "CHGA,CHGB,CYB561A3,SCG2" Drug ctd:C085665 zaleplon CTD 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "GABRA1,GABRA4,GABRB1,GABRG2" Drug CID000051701 darodipine Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "AGT,APC,CACNA2D1,CALB1" Drug CID000006471 alphaprodine Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "PNMA2,PRODH,SYNE1,ARHGAP9" Drug ctd:C475726 "APETx1, Anthopleura elegantissima" CTD 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "KCNH2,SCN2A,SCN3A,SCN8A" Drug CID000037015 cartazolate Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADORA1,ADORA2A,ALDH7A1,ZMYND10" Drug CID000563154 ETH157 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ATP1A1,ATP1A2,ATP1A3,ATP1B3" Drug CID000032800 Kinevac Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "ADRB2,CCK,CCKBR,EFS" Drug CID003017129 4-phenylpiperidine-4-carboxamide Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "B3GAT1,TAC1,TAC3,TACR1" Drug CID000133071 Bq 928 Stitch 7.01E-03 1.00E+00 3.49E-02 3.97E-01 4 6 "EDN1,EDN3,EDNRA,EDNRB" Drug CID000004184 mianserin Stitch 7.04E-03 1.00E+00 3.51E-02 3.99E-01 23 87 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,BSN,CCK,CHRM1,DRD1,DMTN,ZMYND10,LOXL3,CIT,HRH3,HTR2A,HTR5A,KCNH2,MAOB,SLC6A11,SOX10,TRH" Drug 4994_UP "Clomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.11E-03 1.00E+00 3.54E-02 4.03E-01 42 184 "ASIC1,KIDINS220,CDC14B,SEMA4G,RGS20,PLA2G4C,ALDH7A1,BAIAP3,MTMR7,SLC16A4,SYNGR3,CLCN4,SNCAIP,OSBPL3,CNTNAP2,DCT,ATN1,RCAN1,EFNB3,C3orf18,GPR153,ATP8A2,SRCAP,RND1,GNAS,GRB10,NEFM,NPR2,OGG1,PIK3CD,MTRF1L,CARF,SCN2B,SLC1A7,CDK19,WSCD1,PCDHGA10,TPM3,TRIO,VIPR2,MKRN3,SEMA3B" Drug 1772_DN Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; HL60; HG-U133A Broad Institute CMAP Down 7.11E-03 1.00E+00 3.54E-02 4.03E-01 42 184 "ACLY,ADD3,OGT,GAS7,APP,ARNTL,CFLAR,CANX,CNOT8,NIPBL,APPL1,GIT2,ABI1,RCAN1,DCTN4,ENO2,F3,OGA,GLUL,STMN1,MBD1,P2RX7,PLCD1,LRP12,RDX,TMEM156,DOCK10,FBXO11,WDR37,CCDC88A,RCOR3,TAB2,NXT2,MAPK8IP3,ANKRD12,WASHC4,TPM4,TSN,NSD2,CLDND1,ZNF24,EVI5" Drug CID003363161 AC1MO44G Stitch 7.15E-03 1.00E+00 3.56E-02 4.05E-01 24 92 "AGT,ALK,ATM,BBS2,DST,RUNX1T1,CHRM1,CHRNB2,CNR1,SRGAP3,EDN1,EDN3,F8,FDFT1,MX1,PMP2,MAPK8,MAPK9,MAPK10,NDUFS7,PTAFR,TAC1,TAC3,WNK1" Drug CID000449625 AC1L9NBR Stitch 7.15E-03 1.00E+00 3.56E-02 4.05E-01 24 92 "ADORA2A,AQP6,ABCG2,SLC29A4,EPB41,TUBB3,GYG1,HRH3,KCNQ2,NELL1,NPY,OPRL1,P2RY1,TMOD2,ABCB1,TACR1,ANO4,TLR4,TMOD1,TPM1,TPM2,TPM3,TPM4,WNK1" Drug 6606_UP Omeprazole [73590-58-6]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "NDRG2,ADD2,PLA2G6,SEMA6A,DOC2A,DDO,ATP1A3,ATP2B3,CADM3,MTMR3,CACNA1G,SLC4A8,CYBB,SPOCK3,SRGAP3,DSCAM,DTNB,EDNRA,ELN,RASGRP2,EFCAB2,GABRA5,SRCAP,ATF7,FAM107A,C2orf72,KCNJ5,PACRG,MGAT3,AFF1,MMP16,MOBP,NF1,NPPA,PACSIN1,PPP1R1A,EMID1,SLA,KIF13A,DOK5,ZHX3,ACSBG1,THRA,AMACR,JPH3" Drug 3080_DN Thonzonium bromide [553-08-2]; Down 200; 6.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ABHD6,ADRA1D,AMPD3,APC,PPP4R4,KIF1A,BMP7,HIP1R,B4GALT6,AKAP7,SLC4A7,ZNF337,RIMS3,DGKG,CTIF,TNK2,FCGRT,FECH,IQCG,GABRA2,HTATSF1,GPD2,MAP4,NINJ2,CNOT4,NPR2,PDE4A,CDK14,CCSER2,MAPK7,PTAFR,PLPPR1,RAB3IL1,BEND5,SBF1,BTBD7,MAPKBP1,MAPK8IP3,KANK1,DNMBP,PDLIM2,NSD1,TGFBR3,TPM3,ST7" Drug 2061_DN Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ARID1A,ADD3,PKP4,APP,MARK4,BACH1,SPAG9,LRRFIP1,NIPBL,FAM169A,ARHGEF4,KIAA0753,PARD6A,LPAR6,F8,NBEA,PDLIM5,FYN,SPIN1,GPD2,BTN2A1,RNFT2,MAN2A2,NOVA1,MINDY2,MAPK7,RAP1GAP,RIC8B,RXRA,SLC1A3,KBTBD4,SMARCC2,LIMCH1,KDM4B,SON,FNBP1,SYNE2,VPS13A,EXOC7,SATB2,ARHGEF12,NAV3,FIP1L1,PLSCR4,SSPN" Drug 6284_DN Acetaminophen [103-90-2]; Down 200; 26.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "KCNAB2,APP,ARNTL,ASPH,ADAM15,CFLAR,CNOT8,HOMER3,SLC4A7,SLITRK5,PPP6R2,DBT,RUSC2,SGSM2,OPTN,LRRC23,TRAF3IP2,HBS1L,B4GALNT1,ERAP1,GART,AHDC1,TXNL4A,GLYR1,GLS,GNAS,GNG4,KCNMA1,MAN2A2,PDE1C,PSMD13,PTPN13,RAP1GAP,GAL3ST4,CSRNP3,LIMS2,ARHGEF40,SLC14A1,GLT8D1,ZBTB43,ELOVL4,WSCD1,PARD3,UPF3A,MAP3K12" Drug 6359_UP Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "OGT,APC,ATP2B2,KIF1A,BMP7,CDH10,B4GALT6,LHX2,TPP1,DNAJB5,SH2B1,NCOR2,VCAN,RIMS3,E2F5,PLXNC1,TENM1,F3,OLFM1,SCARA3,FOXG1,FYB1,SIGLEC8,PADI2,MDFI,ZNF862,NF1,SETD4,KHDRBS2,RIC8B,ATXN7,FRMPD1,CNKSR2,SLC1A7,ELMO2,KDM4C,SS18,ADGRL3,R3HDM1,TRIO,VGF,XRCC4,REEP1,SYNC,PHTF2" Drug 7291_DN Lymecycline [992-21-2]; Down 200; 6.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "AP2A2,FAM131A,PPFIA3,ARRB2,ASPH,C5,SRSF11,NIPBL,AKAP7,HDAC4,ZBTB24,SMG7,DNM2,APH1A,EIF5,EML1,VPS26C,NBEA,FAM49B,GLS,PRRC2B,NUDT21,GRB10,IL6ST,JAK2,NUMA1,PDE1C,PRKAB2,RAP1GAP,GTDC1,PPP1R9A,SMARCC2,SMARCD3,CAND2,KDM4C,LARP4,ELOVL4,CEP68,IQCE,TBL1X,ARHGEF12,TRIO,SSBP2,MAP3K12,PCBP4" Drug 404_UP wortmannin; Up 200; 0.01uM; ssMCF7; HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ADD2,ADRB2,PLA2G6,RASL11B,MYRF,HAP1,INA,DLGAP1,STOML1,ARHGEF6,DCC,TMCC2,USH1C,EFNB3,LRRC23,IGSF6,C1orf61,CYP46A1,AHDC1,RUNDC3A,HMX1,LAMA2,STMN1,MGAT3,N6AMT1,NFIX,TREM2,GPR173,FXYD1,ST6GAL1,RPH3A,LIMS2,TSNAXIP1,NMNAT2,IZUMO4,SPTB,SPART,PHLDB1,PCDHA5,TNS1,TRPM2,AMOT,REEP1,TFIP11,PMEPA1" Drug 4014_DN Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ADRA1D,APC,SEMA4G,DNAH17,ALDH4A1,SYNJ2,TAOK2,ARHGAP22,WHRN,CRMP1,MFAP3L,MRNIP,MTSS1L,EZH1,FGF1,AFF2,C1QL1,MSL3,POLL,KLF12,ICA1,SHISAL1,MAPT,ADAM22,NOVA1,OPCML,PBX1,EPN1,SNRK,PEX5,ZCWPW1,ENOX1,KHDRBS2,RGS7,KCTD17,ZNF821,AMBRA1,PKNOX2,SLC6A9,ZNF667,SNCA,TSNAXIP1,THRA,RPRM,SH3GLB2" Drug 2948_DN Levocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ACTN1,APBB2,GAS7,CASK,ASPH,RIPK1,CFLAR,SCAPER,OSGIN2,CLGN,BAG4,CHD1L,PPP1R16B,TM9SF4,KIAA0586,DAPK3,RUSC2,PLEKHO1,STX2,PDLIM5,ZNF44,INPP5K,GPD2,NEK1,NFYA,STRN3,RC3H2,PTPA,RAP1GAP,RGS10,FBXW7,ITSN1,NUBPL,SLC6A8,KDM4B,ZCCHC24,SYT11,DNMBP,TCF7,SYNE1,KAT6B,TNS1,ATP6V0E2,SYNC,NLRP3" Drug 3052_DN Esculin Hydrate [531-75-9]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ARID1A,TRMT9B,ANK3,NRP2,KSR1,CACNB2,HIP1R,AP4M1,CDH8,PDE4DIP,SPATA2,RUSC2,EXOG,DTNA,EEF1A2,MBNL2,SORBS3,DLC1,GABRA2,ZMYND11,SEPT9,INPP5K,WASF3,PRRC2B,GPM6B,SPACA9,GSN,ST8SIA5,SLC25A23,PLTP,PTCH1,KHDRBS2,CARF,FOXRED2,RASA3,UNC5B,RGL1,EXOC7,TCF4,DMXL2,TCF7L2,TPM1,TRPS1,KCNAB1,SSPN" Drug 6333_DN Piribedil hydrochloride [78213-63-5]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "MRTFA,EP400,APBB2,ARHGAP5,KRIT1,CNOT8,CLU,QKI,AKAP7,SLC4A7,HAPLN1,INTS1,LYPD1,ABI1,LPAR6,TRAF3IP2,ERAP1,GART,GLI2,GPM6B,GPER1,NUDT21,ARHGAP19,JAK2,L1CAM,MAN2A2,SLC11A2,SLC25A23,LRP12,ING3,RGS10,CLIP1,SUPT20H,WDR37,PEX26,CDK5RAP2,NXT2,MAPK8IP3,GSE1,PSD3,SLC35G2,CABIN1,FAM155A,XRCC4,SMIM8" Drug 5048_DN Etofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "NME5,TRMT9B,KCNAB2,APC,APLP1,SCAPER,GYG2,AKAP7,CRY2,CNTNAP2,HP1BP3,CHRDL1,TOM1,EDIL3,EDNRA,SGK2,FAM13A,MRNIP,PLEKHO1,EPHA5,FOXG1,SEMA4D,TMEM8B,SRCAP,CNTRL,ZNF862,SERPINI1,PIK3R1,SLC25A23,KLK6,CNNM2,PTN,RAD52,RAP1GAP,KIRREL1,RXRA,MAPK12,SCN8A,FUZ,ST6GAL1,DZIP1,CADM1,KLC2,ZNF32,EVI5" Drug 377_DN celecoxib; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "MTUS1,ALAD,PPFIA3,ARRB2,MARK4,SLC4A4,EPS15L1,SLC24A2,STOML1,FAM189A2,CHD1L,RIMS2,HS3ST2,DTNA,DCTN4,SRCAP,GLS,PCSK1N,PRDM5,MAP4,MOBP,MYT1,NEFH,NTRK3,GPSM2,PLCD1,MBOAT7,PACSIN1,PPP5C,MAPK3,MAPK10,SPDL1,RAP1GDS1,LIMS2,ZSWIM8,ARHGAP26,PLCB1,ANKRD12,MCF2L,WWC1,TCF4,HIF3A,TNS1,ZBTB16,LMAN2L" Drug 4543_UP (cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ACTN2,BCL2L2,GYG2,LDLRAD4,CACNA1A,CCKBR,CBFA2T2,SCARB1,KCNAB3,MAGI1,ADGRG1,CNTN1,SH2B1,DAPK1,SPOCK2,TNK2,REEP2,ZNF589,NSG1,GAP43,DISC1,GLI2,PRUNE2,CACFD1,IGSF1,KCNMA1,ADAM22,NPTX1,PDE4A,PDE4D,PDGFRA,PLCB2,MINDY2,PTAFR,PTPRH,SLC6A15,RGS3,MYH14,PNMA8A,ADGRL3,SZT2,SSBP2,OSBP2,VAV2,MVB12B" Drug 1704_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "APBB2,BCAS1,PPFIA3,PRX,MARCH3,SCAPER,LDLRAD4,ARHGEF1,SOCS6,PLEKHB1,TAOK2,PICK1,SLC4A7,NRG2,LRRC23,ZNF589,FECH,FHL1,SEMA4D,TMEM8B,RUNDC3A,TXNL4A,POLL,GPM6B,DIDO1,MOBP,CDK18,PFKFB2,GDPD2,PTCH1,ELOVL2,SUPT20H,ASAP3,DOCK10,SMARCD3,KIF13A,INKA2,TCF7L2,TRIM2,ZKSCAN5,VIPR2,WIPF1,SPHK2,EMSY,PRDM2" Drug 4372_DN Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "RALGAPA1,APP,CDC14B,PDE8B,HAP1,CRLF1,SH2B1,KBTBD11,DMPK,EDNRA,HIPK3,DMTN,IGSF6,FAM198B,DLC1,OLFM1,FGFR3,KHDRBS3,PCDH17,RND1,GLYR1,GNG4,GPM6B,IL6R,ITIH2,MAPT,MID1,NOS1,RETREG1,NLE1,ZFHX4,RPS6KA2,SELL,ASAP3,CXXC4,SNCA,DOP1A,WDTC1,INKA2,JMJD6,VAMP1,PLCB1,ATP11A,HEY2,FLRT2" Drug 4109_UP Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ACTN2,ADORA1,AMPD3,EPB41L5,N4BP2L1,PROM1,BAIAP3,CAMK2B,CCKBR,TAOK2,AKAP6,DAPK3,SPOCK2,ATN1,EDIL3,SORBS3,MTSS1L,NRN1,PTK2B,CORO2B,FOXF2,GAB1,ALDH1L1,GNAO1,GRK4,GRM7,KCNN1,LSS,CD200,OPCML,PDE1C,RETREG1,CCDC40,TRIM68,SYNDIG1,SNCA,CAND2,ZBTB43,AJAP1,WSCD1,SYNE1,DOCK9,TMOD1,SEZ6L,SSPN" Drug 1235_UP genistein; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ALK,BIN1,GAS7,CDC14B,ZSCAN18,NCOA1,ALDH7A1,KIF1A,GYG2,C5,ARHGEF2,TAOK2,RAB28,AKAP7,CPS1,HAPLN1,TM9SF4,DPH1,HIPK3,SRCAP,C1QL1,GLI2,TDRKH,GSN,NF1,NRGN,NTRK2,OPCML,PFKFB2,PRKAR1B,WDR25,PTN,MCMBP,PAQR6,SUPT20H,SLC4A3,SNCA,KIF13A,KCTD2,PIK3R5,HIRA,UGT8,WNK1,PHTF2,AAAS" Drug 6503_DN Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ADD1,DOC2A,EPB41L5,APOC1,PPFIA3,CDK10,ATP2A2,MTMR2,AP4M1,CDH8,CRLF1,B4GALT6,PLAA,DAPK3,DBT,SMG7,DNM1,CELSR3,ING4,MRNIP,EPB41L2,STX2,BAIAP2,ERAP1,GNG4,VWA5A,MAPT,ZNF862,OCRL,PLXNB1,PPP2R2B,EMID1,FOXRED2,LIMCH1,CLASP2,FAM168A,TACC1,PSD3,TPD52,HIRA,XRCC4,REEP1,SYNC,EMSY,RNF170" Drug 2127_UP Pentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ADCY6,APBB1,APBB2,ALDH4A1,QKI,WHRN,ARHGEF4,DCAF4,EDRF1,EFNA3,PLEKHO1,STX2,FGF1,DENND2A,GAD1,ZNF276,BTN2A1,BACH2,ICA1,TJAP1,IL6ST,JAK2,IPO5,MDFI,GIT1,CNOT4,NRGN,CNNM2,SH3TC2,TTLL7,MAPK12,DZIP1,SAMSN1,TTBK2,COBL,IQCE,SMG6,KIAA0930,TIAM1,MAP3K12,EMSY,PRDM2,HPS4,KCNAB1,PHTF2" Drug 7501_UP Suramin sodium salt; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "MRTFA,AMT,CDC42BPA,NCOA1,MTMR9,ARHGEF2,DNAJB5,VCAN,HDAC9,DPH1,SIDT2,MBNL2,ING4,COQ7,ETV1,FGF13,FOXG1,FYB1,DENND2A,CNTRL,SLC2A6,HNMT,INPP5B,LIG4,TAGLN3,PPP5C,ELOVL2,RGS4,FUZ,ELMO2,SLC22A4,KDM4B,DDN,SEPT8,VPS13A,IQCE,TCF7L2,SLC35G2,GPR161,R3HDM1,ZMYND8,HIRA,LMF1,PCBP4,PHTF2" Drug 6152_DN Piperacetazine [3819-00-9]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ASIC1,ARID1A,APP,ATP2A2,COL9A2,SH2B1,CTNND1,DBT,RUSC2,CELSR3,PIPOX,INPP5K,AHDC1,ADAM28,POLL,GNG4,GRIK5,MAP4,SCAMP5,MID1,OMG,PDE4A,PTK2,PTPN13,MARCH1,RAB3A,ZNF493,TMEM206,TCP11L1,MAP6D1,FOXRED2,FAM102A,TMCC1,COLGALT2,NCDN,STX1A,DNMBP,ZNF34,THRA,FLRT2,VIPR2,LMF1,TRIM9,ZBTB38,EVI5" Drug 1164_UP nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "MTUS1,AGT,C1QTNF3,KSR1,SYNJ2,CACNA1I,CACNA1A,SOCS6,CREM,MAML1,CTIF,DPH1,MRNIP,RASGRP2,RRAGB,ALDH1L1,MAP4,MATK,NF1,NOS1,NPR2,PDE3B,PLCD1,STRN3,POLG,SYTL2,GON4L,TMEM231,MAP6D1,GALNT10,FUZ,PPP4R3A,RIMS1,PEG10,DBNDD2,SPTB,ANKRD12,CAMSAP2,FBXW11,TBL1X,TCF7L2,ARHGEF12,TNS1,PLPPR2,WNK1" Drug 6266_UP Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ACTN2,MPDZ,MTMR2,BTRC,SCARB1,QKI,FAM169A,GREB1,LYPD1,PARD6A,TMCC2,RCAN1,EGR3,RGS17,STX2,BAIAP2,SIGLEC8,IL6ST,KCNJ3,KCNN1,MAP4,PDE3B,PDE4A,RETREG1,MAPK7,ELOVL2,ATG16L1,BSDC1,RGS10,RGS12,GSTCD,LGR4,SGK1,FBXO11,NUBPL,SLC20A2,ZSWIM8,SPTAN1,TRIM2,VIPR2,XRCC4,ZNF45,ZNF189,MAP3K12,EPM2A" Drug 2973_UP Pivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "AMH,DDX3Y,ADGRB1,CACNB2,ZFYVE9,DGKG,MAGI2,SORBS3,TNK2,VPS13B,RASGRP2,ERCC2,IGSF6,GPR153,NEU3,ZNF276,KCND3,KCNJ5,MGAT3,AFDN,GIT1,NUMA1,CDK14,FXYD1,PILRA,PRKCZ,RELN,DEF8,WDR25,PTAFR,TMEM206,MRAS,CCDC88A,TMCC1,IZUMO4,IQSEC2,FCHO1,TBCEL,TCF7,SYNE1,CRTC1,ZNF34,RBFOX2,FLRT1,ST7" Drug 3405_DN Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "PPFIA1,APC,APOC1,ARRB1,BCL7A,CFLAR,SYNJ2,GYG2,VAX2,PDE4DIP,INTS1,SMG7,F3,B4GALNT1,SRCAP,TXNL4A,SLC2A6,HNMT,MAP4,ADAM22,NF1,NRCAM,NUCB1,LRP12,MBOAT7,TNPO2,FSD1,CNNM2,ATG16L1,PAQR6,ITSN1,BTBD7,ARFGAP1,MAPKBP1,ZHX3,SS18,NXT2,NCDN,ASTN2,DDHD2,TRIM2,TNS2,SIK3,HIRA,SEMA3B" Drug 6449_DN Rolipram [61413-54-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "KIDINS220,AK2,SEMA6A,AMH,APBA2,CDK10,FEZ1,SIPA1L1,PDE4DIP,GREB1,GIT2,LYPD1,TOM1,DMTN,GPHN,SCML2,FHL1,DISC1,INPP5K,MALT1,GLS,MAP4K5,RASSF8,HSD17B1,IDH3A,DIPK1A,KCNH2,VWA5A,MGAT3,ZNF862,NF1,NPR2,NPTX1,LRP12,PPP5C,TMEM231,WLS,PEX26,ZKSCAN3,ZBTB43,MAPK8IP3,TACC1,SEMA4A,SSBP2,KCNAB1" Drug 6676_DN Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.20E-03 1.00E+00 3.58E-02 4.07E-01 45 200 "ARID1A,ADD2,MARK4,BRINP2,ATM,ADAM23,MTMR3,MYRF,CHN2,PLAA,CPS1,HAPLN1,AATK,PDE4DIP,SDC3,EDNRA,CELSR3,DCTN2,SEPT9,ZNF276,GNAL,HLF,HSF2,TJAP1,NOVA2,PPP5C,GRAMD1C,PTPRE,PID1,SEC61A2,KIRREL1,ANKRD6,SLC20A2,CAMTA2,THSD1,MAPK8IP3,VPS13A,TBCEL,TNS1,ZKSCAN5,ZBTB14,ZNF711,TFIP11,NT5M,FZD3" Drug ctd:C046243 tryptanthrine CTD 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "GAP43,MAP2,MAPT,MYCN,NEFH,ABCB1,SST" Drug CID000324081 4-anilinoquinazoline Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "ABCG2,EGFR,ERBB2,ERBB4,FLT1,KIT,RET" Drug CID000008010 propanedinitrile Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "ACHE,EGFR,ERBB4,PNMA2,HRH3,PLEC,SYNE1" Drug CID000017434 AFOs Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "SEMA6A,DYNLL1,CHN1,GNE,EFS,MYH6,SHANK2" Drug ctd:D018750 "6-Cyano-7-nitroquinoxaline-2,3-dione" CTD 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "PPP1R1B,GFAP,GRIA1,GRIA2,NEFM,MAPK3,TAC1" Drug CID000011000 tropylium Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "APP,ARSE,F3,POLL,PMP2,SALL1,SYNE1" Drug CID000003290 ethopropazine Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "ACHE,ALCAM,ATM,BCHE,CHRM1,GRIN3A,GART" Drug CID000004617 P858 Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "TOX,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000019966 hex-2-ene Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "ACHE,BCHE,RGN,HRH3,KCNJ3,NBL1,SYNE1" Drug CID000126239 LY233536 Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "GLRB,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,KITLG" Drug CID000052919 haloperidol decanoate Stitch 7.26E-03 1.00E+00 3.60E-02 4.10E-01 7 16 "DRD1,PPP1R1B,GAD1,GAD2,PDYN,PENK,ACSBG1" Drug CID000072430 MDL 28170 Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 16 54 "ANK2,APLP1,CAST,AIFM1,CTNND1,EPB41,PTK2B,STMN2,GRIA1,GRIA2,GRIA4,GRIK1,NEFM,NEFH,PKM,SPTB" Drug CID000005987 sulfamate Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 16 54 "SLC12A5,PLA2G6,SLC4A4,CA4,CA12,CALM1,NPIPA1,SLC12A6,MEST,PTCH1,PTPRB,FBXW7,SLC12A2,SLC12A4,P2RY12,ST8SIA2" Drug CID000447083 S)-ACPA Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 16 54 "ADORA3,C5,CNR1,SIRPA,CALCRL,GRIA1,GRIA2,GRIA4,GRM2,GRM3,KITLG,MX1,PMP2,SP2,NSD1,PCDH15" Drug CID000005621 AC1L1KRB Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 16 54 "CDC42,EDN1,EDN3,EDNRA,EDNRB,GRM5,SCIN,OPRL1,OXTR,P2RY1,PLCB2,RYR1,RYR3,PLCB1,TIAM1,CABIN1" Drug CID000001833 5-methoxytryptamine Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 16 54 "ADCY5,ADCY6,ADCY8,AMT,DMTN,INPP5K,MALT1,LOXL3,HNMT,HTR2A,HTR5A,MAOB,RPE,WDTC1,SYNE2,TACR1" Drug CID000008202 methyl 9-octadecenoate Stitch 7.27E-03 1.00E+00 3.61E-02 4.10E-01 28 112 "ABR,ABHD6,AQP4,ALDH4A1,SGCE,CAPN3,RGN,YTHDC1,DMD,DTNA,ABCC9,F8,FKTN,PDLIM5,GABRA3,MEF2C,NAP1L1,PIK3C2A,PRODH,APTX,RFX2,RFX4,RFX5,SNRPN,SPTB,SYNE2,SYNE1,TMPO" Drug CID000009256 thiazole Stitch 7.28E-03 1.00E+00 3.61E-02 4.11E-01 27 107 "ADORA3,DYNLL1,MTMR2,NFS1,PDE4DIP,WDR20,EGFR,EN2,EYA1,GMPR2,HVCN1,TPK1,GART,TXNL4A,GRB10,IGFBP1,MAOB,MYCN,ENPP2,PSAT1,SH3TC2,SUGCT,TMEM100,SLA,SP2,TAC1,IFT88" Drug CID000008058 hexane Stitch 7.29E-03 1.00E+00 3.62E-02 4.11E-01 19 68 "RALGAPA1,ABHD6,AMT,ARSE,CRYM,PITPNM3,GREB1,POLK,DNER,CDH20,KCNH1,ASPRV1,MID1,NEFM,PDCD2,CLSTN2,GPR161,TP53BP2,GAN" Drug 5074_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.29E-03 1.00E+00 3.62E-02 4.11E-01 41 179 "ASPHD1,MRTFA,APAF1,APOC1,NRP2,CACNA1A,CALB1,CBS,CCKBR,ARHGEF2,WHRN,SLC4A7,CTH,HDAC9,COQ7,SYT17,ATP8A2,GFER,STMN2,TJAP1,KCNC1,MATN3,NEFM,NPPA,MTRF1L,PTPRH,PTX3,PID1,RAD52,RALGDS,RASGRF1,RGS4,KCTD17,RASA3,CPEB3,KDM4B,DDN,SYT1,COBL,KLHL4,VGF" Drug 5691_UP Hycanthone [3105-97-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.29E-03 1.00E+00 3.62E-02 4.11E-01 41 179 "CDC42BPA,DDX3Y,N4BP2L1,RGS9,CFLAR,CFAP410,RCBTB2,FAM149A,WHRN,CHD5,NRN1,FGFR3,CAMSAP1,DPYSL4,SESN1,GLS,NR3C1,TJAP1,IL11RA,INPP1,KCNH2,MN1,NPTX1,PDE4A,SERPINI1,PLCD1,PMP2,LRP12,C19orf57,POU3F4,PTPRO,RALGDS,C1orf54,SLC2A5,SLC11A1,ZCCHC24,ZBTB43,PHLDB1,ZMAT3,ZNF711,SLC30A3" Drug 1175_DN "Trichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 7.29E-03 1.00E+00 3.62E-02 4.11E-01 41 179 "ARID1A,AMPD3,CFLAR,MAP7,RCBTB2,NIPBL,VCAN,RASSF2,SIRPA,ZEB2,FGR,SYNCRIP,STAG2,ZMYND11,GRB10,DIDO1,IL6R,LMO2,SMAD1,MBP,MEIS2,ENPP2,PIK3CD,FAM216A,ATP8B4,SAFB,FBXO11,SLA,SCMH1,GSE1,ZC3H4,TMPO,ZMYND8,LAT2,ZBTB14,LRP8,PRDM10,NAV3,EPM2A,ST7,NETO2" Drug 3887_UP "Camptothecine (S,+) [7689-03-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A" Broad Institute CMAP Up 7.29E-03 1.00E+00 3.62E-02 4.11E-01 41 179 "ASIC1,AMH,GAS7,ASPH,RASL11B,ATP2B2,CACNA1I,CHI3L2,CHRNB2,TAOK2,RAB33A,CABP1,DAPK1,BRINP1,EDN1,AASS,EIF5,ELN,EN2,RCAN2,CEND1,FGFR3,FOXG1,PCDH17,IRF8,ITGA7,OPRL1,CLDN11,PYGM,RPS20,SGK1,DDN,MAPK8IP3,JMJD6,ARC,TAC3,CUX2,ICAM5,NR2E1,UCHL1,SLC17A7" Drug CID000010438 phorone Stitch 7.35E-03 1.00E+00 3.64E-02 4.14E-01 14 45 "CDO1,CTH,AASS,GGT7,GGT5,GPT2,NR3C1,NFE2L2,MAPK8,MAPK9,MAPK10,GSTCD,CLSTN2,ADHFE1" Drug CID000000320 NSC277817 Stitch 7.35E-03 1.00E+00 3.64E-02 4.14E-01 14 45 "ADAR,ADARB2,BRAP,AMPD2,AMPD3,ENTPD2,GDA,CIT,KLHL23,MATN3,PCMT1,PKM,SARS,DDN" Drug CID000009433 aminophylline Stitch 7.35E-03 1.00E+00 3.64E-02 4.14E-01 14 45 "RALGAPA1,ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ARHGDIG,ALDH7A1,CCK,NR1D2,PDE3A,TMPO,PDIA2" Drug CID000146390 benzophenone-4-maleimide Stitch 7.35E-03 1.00E+00 3.64E-02 4.14E-01 14 45 "ALDH7A1,CALM1,KRIT1,POLK,CNDP1,GSN,POLG,REV3L,SMG6,TNNT1,TPM1,TPM2,TPM3,TPM4" Drug CID000449245 1yej Stitch 7.35E-03 1.00E+00 3.64E-02 4.14E-01 14 45 "DCTN1,B3GAT1,GFAP,CIT,MBP,MITF,NEFM,NEFH,NF1,PDGFRA,PSMA6,LRRC4,CABIN1,UBC" Drug ctd:D019311 Staurosporine CTD 7.38E-03 1.00E+00 3.65E-02 4.15E-01 36 153 "ACHE,SLC12A5,ADRA1B,APP,ATP2A2,BID,CHRM1,BAG4,ELMO1,EDN1,EDNRB,EGFR,F3,SYNCRIP,GFAP,PPARGC1A,FERMT2,IGF1,ITGAM,MAPT,MARK1,NEFM,NFE2L2,NPPA,PKM,PPP2R2B,PPP3CA,MAPK3,MAPK8,RET,SNCA,SPTAN1,TAC1,SIRT1,THRA,TJP1" Drug CID006325610 melanin Stitch 7.39E-03 1.00E+00 3.65E-02 4.15E-01 50 227 "SLC24A4,AMH,CANX,AIFM1,NOG,CHGA,MYRIP,DCT,BLOC1S6,EDNRA,EDNRB,ENO2,TUBB3,CAP2,B4GALNT1,GBX2,GFAP,MCHR1,TNFAIP8L3,IGF1,KIT,MAOB,KITLG,MITF,SCG3,MYO5A,NF1,NPY,NPTX2,NUCB2,PAH,POU3F2,PPP3CA,RET,S100B,SLC8A1,TMEM132D,SNCA,SOX10,NCDN,ABCC8,SYP,SYPL1,MGRN1,TPCN2,UCHL1,MFF,SLC17A7,SLC17A6,IFT88" Drug 6661_DN Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ARID1A,ALK,MRTFA,AMPD3,APAF1,APC,ARRB2,SLC4A4,ALDH7A1,CBFA2T2,CLCN4,GIT2,RUSC2,EDIL3,ING4,COQ7,KIAA1109,SEMA4D,TRMO,TRAF3IP2,GRIK2,SYNPO,MPP2,MX1,NF1,NFYA,POLG,MAPK7,MAPK8,ELOVL2,GTDC1,GSTCD,ZNF821,ASAP3,AMBRA1,PREX2,PPP4R3A,TMCC1,TBCEL,TIAM1,UBTF,VGF,SEMA3B,NAV3" Drug 1922_DN Khellin [82-02-0]; Down 200; 15.4uM; PC3; HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "PPFIA1,PTBP2,CAMK2G,KRIT1,SOCS5,DZIP3,KCTD3,ACSL4,SEC23B,CAP2,SMC2,STAG2,NCKAP1,DBF4,KTN1,LAMP2,MID1,NAP1L1,NUCB2,PIK3C2A,PLCD1,POLG,PPM1B,PPP3CA,C1orf109,REV3L,RFX5,MYH14,UEVLD,WLS,SCG5,SON,FNBP1,GLT8D1,UHRF1BP1L,PEG10,EPB41L3,GSE1,DOCK9,SIRT1,TRPS1,ZNF184,ZNF189,NAV3" Drug 3179_DN Quinacrine dihydrochloride dihydrate [6151-30-0]; Down 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ABR,ABHD6,ADCY6,OSBPL1A,C1QTNF3,LTBP4,APC,APP,STOML1,ABCG1,DZIP3,DCAF8,RABGAP1L,EDNRA,EFNA3,SORBS3,MRNIP,LRRC23,ERBB2,F3,RACK1,FGFR1,GPR19,HNMT,IPO5,LMO2,MAPT,MDM4,MIA2,RETREG2,MBOAT7,MAPK7,CNNM2,RAD51D,FOXRED2,SLC1A7,THSD1,MAPK8IP3,ARHGEF9,SLC44A1,TSC1,VAV2,LMF1,ZNF45" Drug 2971_DN Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "MTUS1,ARRB1,DNAH17,MARK4,SLC4A4,ADAM15,BMP7,STOML1,IQCK,RCHY1,CREM,CRY2,SIDT2,ZNF589,FHL1,NBEA,GALC,INPP5K,GLYR1,DHX35,N6AMT1,NNAT,CNOT4,NUCB1,PDE4A,PFKFB4,PIK3CD,RAD52,MAP6D1,SLC1A7,SLC20A2,TMCC1,DOP1A,EMC1,DDN,SS18,ATP11A,NSD1,THBS4,TPD52,REEP1,NT5M,PLSCR4,AAAS" Drug 3977_UP Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "DDO,AQP4,ARHGDIG,CACNA1I,CFAP410,THSD7A,CAMK2B,CCKBR,CDH18,LHX2,FADS2,FAM149A,WHRN,TOX,BRINP1,SPOCK3,NTM,TRAPPC9,EDN3,FHL1,FOLR2,GAD1,LYVE1,GPR75,GRM8,KCNMA1,LAMA2,MYT1,NTRK2,PAX6,PMP2,POU3F2,SAMD9,PTAFR,TMEM206,KCNIP1,ZFP2,ASAP3,ZNF415,JMJD6,TMOD1,R3HDM1,TNS1,NT5M" Drug 4333_DN PHA-00851261E [724719-49-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ADRA1D,SLC4A4,STX16,SPAG9,ARHGEF1,CLCN4,HOMER3,MICAL2,RUSC2,SRGAP3,ATN1,EGFR,CGREF1,ZMYND11,TMEM8B,GBX2,AHDC1,GLS,ITGA7,JAK2,KCNN1,VWA5A,MAPT,MEF2C,GIT1,NF1,NTRK2,NUCB1,OCRL,PDE4D,PFKFB2,MAPK3,MAPK7,SAMD9,WDR25,PEX5,SMARCA4,SS18,NXT2,EXOC7,TRIO,ZMYND8,UBTF,KLC2" Drug 2025_UP Chlorhexidine [55-56-1]; Up 200; 8uM; HL60; HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "CDC42BPA,APBB2,APP,ARRB2,ALDH4A1,RAB29,WASF1,CAST,CDC27,CDC42,CHRNB2,PCYT1B,SLC4A7,FEZ2,SOCS5,CTH,DCAF8,BAIAP2,FYB1,LAMP2,MT1M,LYRM9,NUCB1,NUCB2,SETD4,OCRL,ZNF426,STRN3,CEP41,RET,AP1AR,ZNF821,SH3BP2,ELMO2,CEP68,VPS13A,SIN3B,TCF7L2,WASHC4,ARHGEF12,CRTC1,SEZ6L,NPL,XRCC4" Drug 2705_DN Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ADRA1D,KIDINS220,APAF1,APBB2,CDK10,PPP4R4,ATP2B1,SYNJ2,CACNA1A,CLGN,NRG2,SH2B1,RUSC2,DTNA,EFNA3,RRAGB,LILRA2,SMAD1,NDUFA5,NINJ2,OGG1,OLR1,PENK,CCSER2,SLC25A23,MED1,ZSCAN32,FAM120C,PEX5,RAB3IL1,TCP11L1,SCG5,SH3BP2,DOCK10,FBXO11,VAMP1,CAMSAP2,TCF7L2,PSD3,RBFOX2,CLIP2,MAP3K12,UBE3B,PHTF2" Drug 6754_DN Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "NDRG3,BIN1,APOC1,PDE8B,ASPH,ATM,STX16,CACNA1I,CANX,CBFA2T2,ARHGEF2,CHM,PLAA,RAB26,ENTPD4,NCOR2,CNTNAP2,DCAF8,SMG7,RCAN1,HSD17B14,ANKFY1,FYB1,GLRB,GPD2,LPAR4,GRK4,MIA2,SCAMP5,MN1,NF1,CNOT4,PIK3R1,ZSCAN32,FBXW7,PAQR6,FOXRED2,CSRNP3,CCDC88A,ZBTB43,LHPP,BEX4,WNT7A,PHTF2" Drug 4794_UP Diflunisal [22494-42-4]; Up 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ADCY6,OSBPL1A,RGS20,BRINP2,BACH1,BTRC,SCARB1,PLEKHB1,TPP1,COL9A3,CHD1L,CTH,SPOCK2,GIT2,KIAA0753,EPHB1,SPEG,SCML2,ZNF589,KIAA1109,FGF1,FGF13,IQCG,ATP2C1,ICA1,KCNH1,ADAM22,NF1,NUMA1,PLCD1,NUDT11,TCP11L1,SH3GL3,ASAP3,PPP4R3A,WDTC1,UHRF1BP1L,AJAP1,ARHGEF12,BEX4,TPD52,VAV1,ZNF24,RNF146" Drug 1968_DN Minaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; HL60; HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ALAD,APBB2,APP,SEMA4G,PDXK,N4BP2L1,ADAM23,ST3GAL5,CAMK2B,RUNX1T1,CD86,SPOCK2,DBT,TRAPPC9,RCAN1,PHF20L1,CEND1,EXTL2,SEC23B,SEMA4D,OGA,GART,LILRA2,ARHGAP19,NEFH,OPA1,PLCB2,SBF1,ATXN2,BCAN,URGCP,SLC11A1,MAPKBP1,DOP1A,SP2,ZSWIM8,SS18,ERBIN,DIP2A,TK2,TMPO,CHST5,UBE3A,RNF146" Drug 6834_DN Pindolol [13523-86-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "AK2,BIN1,CDC42BPA,FAM131A,ALDH4A1,BTRC,FAM169A,RIMS2,GPRASP1,SIDT2,ING4,NCALD,RRAGB,ZNF589,IQCG,TXNL4A,POLL,GNG4,KCNH2,LSS,NF1,NRGN,PDE3B,CCSER2,SLC25A23,PLXNB1,PRODH,RAB3A,RAD52,RGS10,ROM1,NEK11,SH3BP2,BTBD7,SOX3,CDK19,SAMSN1,PLCB1,SEMA4A,PARD3,ZKSCAN5,PLPPR2,GDPD5,SEMA3B" Drug 2240_DN Acenocoumarol [152-72-7]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "NDRG2,KIDINS220,BCAS1,HAP1,ARHGEF2,CDH10,FOXN3,PICK1,TMCC2,CDON,SIDT2,DMTN,EZH1,FHL1,PRELID3A,SEPT9,AHDC1,RAB30,GLS,GNG4,CDK18,PIK3CD,NLE1,TNPO2,PTHLH,RGS3,RGS12,TCP11L1,EPN2,ZKSCAN3,WDTC1,DOK5,TROVE2,PLCB1,ASTN2,ROBO3,EXOC7,WSCD1,TRIM2,TMOD1,MAP3K12,KCNAB1,ST7,PHTF2" Drug 681_DN monastrol; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ACTN1,NDRG2,ADD2,KCNAB2,ARRB2,BCL7A,SLC25A14,CBFA2T2,TBRG4,EPS15L1,CDC42BPB,GREB1,CTNND1,DBT,RCAN1,RASGRP1,EPB41L1,RACK1,KAT8,FGFR1,EVL,FOLR2,PDLIM5,GFER,GNAS,GNG3,KHK,MBNL1,NASP,NUMA1,PACSIN1,CRTAC1,RGS12,RNF220,CASC3,PPP4R3A,ZBTB43,DIP2A,GANAB,KLHL7,JMJD6,KAZN,ZNF74,VPS35L" Drug 2810_DN Vitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ABHD6,APOC1,CA4,CACNA1D,HIP1R,CCNT1,USP2,HOMER3,NCOR1,SOCS5,FAM169A,MED24,ANKMY1,BAIAP2,INPP5K,PADI2,HNMT,ITPKB,ZNF862,PRPH,LRRC49,TMEM104,PTPRE,RAD52,ZCWPW1,GTDC1,SEC61A2,PAQR6,ITSN1,PEX26,ZCCHC24,TTBK2,FAM168A,TBL1X,TCF7L2,TNS2,PCDHA6,TMOD1,KLC2,REEP1,EMSY,HPS4,PHTF2,SSPN" Drug 6662_DN Fluspirilen [1841-19-6]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ARID1A,MARK4,BTRC,CACNA1A,FOXN3,NMT2,PICK1,AKAP7,CREB5,NCOR1,DCAF8,SPOCK3,CELSR3,PLXNC1,TENM1,LRRC23,TUBB4A,EFEMP1,SEMA4D,B4GALNT1,NCKAP1,SRCAP,GRM8,VWA5A,NF1,PDE4D,RAD52,NUDT11,SH3BP2,ASAP3,NLGN1,CDK5RAP2,TMCC1,EMC1,ZC4H2,MAPK8IP3,SYT11,ASTN2,WWC1,SYNE1,TIAM1,CABIN1,TNS1,ZBTB14" Drug 6159_DN Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "KIDINS220,BIN1,CDC42BPA,PKP4,APAF1,CAPN3,SCARB1,CHM,RAB33A,TPP1,CSNK1E,MAML1,CTIF,DTNA,MRNIP,PCOLCE2,ST3GAL6,PCYOX1,PDLIM5,FYB1,HBS1L,GPD2,LILRA2,LPAR4,SPACA9,ATXN2L,IL6ST,NUMA1,CCSER2,PTPA,SIDT1,RAD52,AMBRA1,FBXO11,CCDC88A,SON,PRRC2C,TBL1X,EHBP1,TCF4,TCF7L2,TEX15,TPM2,WNK1" Drug 5252_DN Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ALCAM,SYNJ1,CFAP410,CACNA1D,SOCS6,HOMER3,NOS1AP,JAKMIP2,HIPK3,MBNL2,KIAA1109,FGF13,EFCAB2,TRMO,GNG4,GPER1,NUDT21,MAP4K5,HNMT,IL6ST,INPP5B,JAK2,KITLG,MMP16,MPP2,ADAM22,NF1,NFYA,CNOT4,RAB3IL1,TCP11L1,CXXC4,WDTC1,ZCCHC24,ZC3H13,TROVE2,ST5,PLCB1,AP4E1,RBFOX2,KCNK12,SYNC,PHTF2,SENP7" Drug 7327_DN Etofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "CDC42BPA,APOC1,PPFIA3,NCOA1,HOMER3,AKAP7,BAG4,CREM,DTNA,SIDT2,CDKL3,SCML2,INPP5K,GLYR1,HSD17B1,LIG4,MAP4,MATK,KITLG,NUMA1,STRN3,PRKAB2,LRRC49,TMEM231,CEP97,ACSS3,RGS3,CLIP1,FERMT1,EPN2,ZSWIM8,THSD1,ARHGEF9,DNMBP,TCF7,TCF7L2,AHCYL2,PARD3,TRPC1,VGF,TFIP11,FIP1L1,SMIM8,AAAS" Drug 3295_DN Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASPHD1,AK2,ANK3,APOC1,PPFIA3,ARRB1,MARK4,ALDH4A1,ARHGEF1,CACNA2D2,RAB28,LRIG1,SOCS5,RIMS3,DBT,DNM2,FGFR1,FGFR3,MSL3,TDRKH,DIDO1,ACOT7,HNMT,HSD17B1,INPP5B,JAK2,MBD1,KITLG,LYRM9,NEK1,NF1,PLEC,FAM184A,TRAPPC13,SUPT20H,SH3BP2,SLC15A2,PLCB1,SEMA4A,CHST8,PLPPR2,XRCC4,PCBP4,SSPN" Drug 2111_DN Methocarbamol [532-03-6]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "BRAP,APBB2,DGKD,MPDZ,MYRF,RAB28,HINFP,VCAN,PDE4DIP,ARHGEF4,INTS1,RUSC2,C2CD2L,RHOBTB1,BAIAP2,MPP6,GAD1,SLC2A6,MAN1B1,KHK,MAP4,MX1,CCSER2,SLC25A23,PTPA,BCAS3,RAB3A,TTLL7,MYH14,ATXN1,FAM102A,ASAP3,AMBRA1,SLC20A2,ARHGAP26,SPTAN1,MAPK8IP3,ZEB1,PARD3,CABIN1,PLPPR2,LMF1,VPS35L,MPPE1" Drug 1269_DN "Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "PPFIA1,APBB2,APP,CDK10,ASPH,NCOA1,ATP6V0A1,CAMK2G,C2CD2,ENTPD4,RUBCN,DBN1,DCTN1,SUGP2,EGR3,ANKMY1,KAT8,FGFR1,KLC1,MAP4,MIA2,ZNF862,NAP1L1,NRGN,PTPA,RAD52,GTDC1,CLIP1,ATXN7,AMBRA1,FAM214B,KBTBD4,SMARCC2,KDM4B,ZCCHC24,SPTAN1,CAMTA2,NCDN,PARD3,TNS1,RBFOX2,UBTF,PRDM2,RTN4" Drug 4309_DN Famprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASPH,STX16,ADGRB2,KRIT1,CLCN4,HOMER3,ARMC8,ABI3BP,ENTPD4,CREB5,SIDT2,EFEMP1,TRMO,ZMYND11,CRCP,GPD2,AGFG1,IL6ST,MAP4,ZNF862,NAP1L3,PDE4D,STRN3,LRP12,PRKAB2,RAB3IL1,BEND5,KIRREL1,ZFP30,PPP1R9A,FBXO11,SEPT8,ASTN2,KIAA1107,TCF4,ZEB1,ARHGEF12,DICER1,TMPO,R3HDM1,SF1,WNK1,PRDM2,KAT6A" Drug 4712_DN 0173570-0000 [211245-44-2]; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "MRTFA,APC,MARK4,SRSF11,FOXN3,SLIT2,QKI,AKAP7,BAG4,PDE4DIP,BRINP1,JAKMIP2,ZNF804A,DTNA,PLEKHO1,ACSL4,SCML2,FGFR3,DPYSL4,PDLIM5,TXNL4A,HSF2,KCNJ3,MIA2,ADAM22,RETREG1,PPARA,RGS12,ARHGEF10L,NEK11,TCP11L1,SH3BP2,FBXO11,SLC15A2,KIF13A,CDK19,SUPT5H,TACC1,IQCE,TCF7,HIRA,ZNF74,KAT6A,TIGD6" Drug 221_UP 17-AAG; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "BIN1,CDK10,MPDZ,KRIT1,ARHGAP33,CACNA2D2,CHRM4,SIPA1L1,SDC3,HDAC4,DNAJB6,ENO2,CDKL3,BAIAP2,AGAP2,SRCAP,GPR37,GRIN1,RNFT2,MAOB,ADAM22,NNAT,SETD4,ODF2,PFKFB2,PLXNB1,TCP11L1,MAPK12,SUPT20H,HSPA4L,SH3BGR,FNDC3A,SLC1A7,SLC12A4,IFT122,KDM4B,CLSTN2,ANKRD12,EXOC7,TRIM2,VIPR2,LMF1,MPPE1,FXR1" Drug 311_UP monastrol; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ABHD6,BIN1,KCNAB2,CDK10,PDXK,ARRB1,ARRB2,CADM3,ATP6V0A1,BAIAP3,HOMER3,SH2B1,ARHGEF10,GIT2,EFNB3,SUGP2,STX2,ERCC2,RUNDC3A,RNFT2,ATXN2L,ITPKB,KHK,L1CAM,ADAM22,ODF2,PRODH,WDR25,SUSD4,PAQR6,FOXRED2,GALNT10,FERMT1,ABLIM3,KDM4B,ZCCHC24,NMNAT2,UNC5B,SEPT8,TRIO,PLPPR2,MAP3K12,NAV2,MPPE1" Drug 4324_DN Acacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "BIN1,AMT,APC,APLP1,SLC4A4,CDK5R1,ARHGAP33,FOXN3,B4GALT6,HAPLN1,SLITRK5,FAM131B,CHRDL1,ATN1,TOM1,TUBB4A,SEMA4D,SRCAP,AHDC1,GLRB,POLL,GSTM5,HSD17B1,TJAP1,NTRK2,PDE4A,FA2H,C1orf54,ROM1,SH3GL2,SLC4A3,SPTB,THSD1,ZEB1,AHCYL2,CABIN1,WBP2,TRIO,VIPR2,LAT2,SPHK2,SEMA3B,NAV3,ZNF248" Drug 6082_DN Tetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASPHD1,ATM,CACNA1D,ARHGEF1,NMT2,CSF1R,SDC3,DAPK3,DBT,ZNF804A,ANKMY1,KAT8,FGFR3,MALT1,GPR37,RASSF8,KPNA5,MAP4,MMP16,LYRM9,SSH1,SLC25A23,PRPH,WLS,ZNF821,SMARCD3,WDTC1,ZCCHC24,IQSEC2,THSD1,VAMP1,EXOC7,AHCYL2,SLC44A1,TK2,PARD3,TRIO,ZKSCAN5,HIRA,CADM1,VIPR2,KLC2,MPPE1,SSPN" Drug 4748_DN "Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ARID1A,NDRG2,DOC2A,GAS7,CDC14B,ST3GAL5,BTRC,FOXN3,SOCS6,FADS2,WHRN,CREM,CRY2,SIPA1L1,DBN1,STX2,ACSL4,FER,SEMA4D,AFF2,OGA,GLS,PCLO,CNTRL,NR3C1,RASSF8,IL6ST,MDM4,PDE3B,ZNF365,PREX2,FAM214B,SHANK2,SMARCD3,EMC1,PBLD,NCDN,ARC,THRA,TMOD1,HIRA,VLDLR,EMSY,PRDM2" Drug 1539_UP Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASIC1,ABHD6,ADORA3,AGT,APAF1,SCAPER,GYG2,USP2,DLGAP1,FADS2,DNAJB5,WHRN,TCEAL2,CSF1R,FAM169A,GREB1,SEC14L5,INTS1,JAKMIP2,MFAP3L,RASGRP2,CDKL3,REEP2,OLFM1,BAIAP2,HPCAL4,C1QL1,ADAMTS13,TJAP1,IPO5,CDK18,SERPINE2,CEP41,RGS3,SEC61A2,SH3GL3,CNKSR2,SHANK2,TROVE2,TIAM1,TK2,RUNDC3B,SCG2,KAT6A" Drug 4003_UP Tolazamide [1156-19-0]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASPHD1,PKP4,BCAS1,MADD,BRINP2,ADAM15,CBS,CBFA2T2,CDC42,VAX2,AKAP5,CSNK1E,CNTNAP2,HIPK3,FGF1,DISC1,ADAM28,GFRA1,GPM6A,MDM4,MEF2C,NF1,NPTX1,PDE2A,PDGFRA,DUSP26,PLCD1,PRKAR1B,RAD51D,C1orf54,BEND5,CSRNP3,ZNF334,MYH15,SOX15,ZHX3,PHLDB1,KAZN,EXOC7,TNS1,TRPC1,WNK1,HPS4,NLRP3" Drug 5299_UP Ciprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ACTN1,NME5,BIN1,APBA2,FAM131A,ALDH4A1,C5,HIP1R,ARHGAP33,STOML1,GREB1,GIT2,ZNF804A,DRD1,F3,BAIAP2,OGA,NCKAP1,ZNF276,GLYR1,FERMT2,MIA2,NFYA,NTRK2,NUMA1,PFKFB3,MTRF1L,MAPK3,RPRD1A,SFPQ,PREX2,FAM214B,CDK5RAP2,SOX3,ZHX3,CLSTN2,POGZ,ELOVL4,PLCB1,CABIN1,ZMYND8,KLC2,HPS4,KAT6A" Drug 7034_UP Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ASPHD1,AK2,ALK,ANK1,APBB2,CFLAR,ARHGEF1,PLEKHB1,AKAP5,MICAL2,DTNA,SIDT2,DMTN,FYN,ERAP1,GPR45,ICA1,ITPKB,KIF5C,MBD1,ZNF862,CNOT4,PDE3B,RC3H2,RAD51D,RAP1GAP,FOXRED2,MAPK12,SBF1,FAM102A,POGZ,TTBK2,PCDHA5,AP4E1,SLC44A1,PARD3,PIK3R5,HIRA,VIPR2,WIPF1,ZNF24,MAP3K12,SEMA3B,PCBP4" Drug 564_UP 15d-PGJ2; Up 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ABHD6,KIDINS220,NR0B1,AQP6,ATM,AZGP1,CFLAR,CAMK2B,ZMYM4,FAM189A2,SEC24C,SGSM2,DLG3,EFNB3,GMPR2,SCML2,PDLIM5,SEPT9,CACFD1,MBP,MMP17,PIK3CD,SPATA6,MBOAT7,MAPK10,GON4L,RALGDS,MYH14,LIMS2,FAM214B,SLC11A1,ATF7IP,ARFGAP1,ZKSCAN3,OGDHL,WDTC1,HECW1,UNC5B,SRPK2,PHLDB1,STX1A,FAM168A,KCTD2,UCHL1" Drug 7101_UP GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "KCNAB2,PPFIA3,MADD,MARK4,ATP2B1,ZFYVE9,STOML1,ABCG2,SLC4A7,CREM,HINFP,CSNK1E,ARHGEF4,PPP6R2,ATN1,USP21,AHDC1,HTATSF1,NR3C1,MUM1,HNMT,DHX35,KIF5C,VWA5A,NAP1L1,NF1,SETD4,PDCD2,PRODH,RIPOR1,CCDC25,SH3BP2,FBXO11,PEX26,BTBD7,ZHX3,IQSEC2,THSD1,PRRC2C,TP53BP1,HIRA,EVI5,EPM2A,SSPN" Drug 6887_DN SB 202190; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "SLC12A5,LTBP4,BIN1,APBB2,ALDH7A1,CFLAR,ARHGEF1,TAOK2,CLCN3,SULT4A1,PDE4DIP,DMPK,MRNIP,DENND4A,FECH,MPP6,DISC1,NR3C1,HNMT,HSF2,TJAP1,LIG4,NF1,SLC11A2,STRN3,RGS10,RNASEL,SEC14L1,ITSN1,AMBRA1,EPN2,RBM34,ZCCHC24,SEPT8,CEP68,VPS13A,ATP11A,TACC1,ANKRD12,HEY1,RPRM,VLDLR,GDPD5,PHTF2" Drug 2622_DN Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ALCAM,ANK3,BCAS1,NCOA1,EIF4G3,CFAP410,PLEKHB1,VAX2,PDE4DIP,GIT2,DBT,HP1BP3,DLG3,EIF5,RGS17,EZH1,FHL1,GPR153,DISC1,POLL,GNG4,BTN2A1,RNFT2,HNMT,BRINP3,MAP4,NFYA,NPR2,PDE4A,ZDHHC14,NEK11,RPS6KA2,ZNF821,TRA2B,SNCA,WDTC1,TSPYL2,ASTN2,MTCL1,TRIO,XRCC4,ZBTB14,EMSY,MPPE1" Drug 7413_DN Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "CDC7,ALAD,ANK3,MPDZ,BCL2L2,TAOK2,STOML1,COL9A2,USP6NL,EDRF1,DTNA,ABCC5,B4GALNT1,GRB10,HMGCL,LSS,MBP,CCSER2,NLE1,SLC25A23,PTPRG,RAB5B,FAM192A,FOXRED2,SH3BGR,FERMT1,ABLIM3,PEX26,SIRT2,SLC15A2,SOX3,UHRF1BP1L,ZBTB43,LHPP,TROVE2,CAMTA2,PHLDB1,VPS13A,ASTN2,TBL1X,TCF7L2,KCTD2,ZNF23,ACTR3B" Drug 5329_DN Erythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "AK2,CDC42BPA,ANK3,PPFIA1,APBB2,ALDH4A1,TAOK2,LHX2,ARMC8,COL4A5,DZIP3,SGSM2,DTNA,OPTN,CELSR3,SUGP2,ENO2,EPB41L1,SEMA4D,DPYSL4,FYN,DISC1,NR3C1,BTN2A1,MAP4,MBD1,NPR2,SLC11A2,FA2H,PRKAR1B,CEP97,RNASEL,SLC22A4,TMCC1,WDTC1,CDK19,ZBTB43,TSPYL2,TRIM2,ARHGEF12,TNS2,KCTD2,KAT6B,CABIN1" Drug 6440_DN AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ACTN2,APC,ATP6V0A1,MTMR7,CBFA2T2,CDH8,TAOK2,TPP1,CNTNAP2,TOX,MAML1,CTIF,ING4,ELN,MTSS1L,NCALD,ZNF549,ALDH1L1,GCNT2,GPM6B,GRK4,ATXN2L,IL6R,IL6ST,KCNMA1,KIF5C,LIFR,PCBP3,ODF2,PCDH9,ENPP2,MINDY2,PKNOX2,FNBP1,HECW1,TCF4,PSD3,SLC44A1,TLL2,TRPC3,REEP1,WNK1,NAV3,KCNAB1" Drug 7504_UP "9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "MRTFA,CDC42BPA,APP,NCOA1,ADGRB2,CA12,MAP7,ARHGEF2,QKI,AKAP7,ABCG1,HDAC9,EDIL3,KAT8,ZNF589,DENND2A,SYT17,SLC2A6,INPP1,IPO5,NLE1,PPP5C,PTHLH,ZDHHC14,CLIP1,SH3GL2,FNDC3A,URGCP,SHANK2,SLC22A4,KDM4B,ELOVL4,SEPT8,VPS13A,SMG6,ARHGEF12,R3HDM1,TSC2,FAM155A,LMF1,ZBTB38,PMEPA1,SEMA3B,PCBP4" Drug 1688_DN Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "ADCY6,AP2A2,AK2,CDC42BPA,CDK10,ARRB2,NUMB,BMP7,SCARB1,HOMER3,PPP6R2,KIAA0586,SGSM2,DMPK,KAT8,TRMO,GPR153,SEPT9,DHX35,HSD17B1,KCNH2,MAP4,MAPT,MIA2,SCAMP5,GIT1,NFYA,NUMA1,SETD4,STRN3,CNNM2,PSMD13,RALGDS,ATXN2,SH3BP2,SLC20A2,ZSWIM8,SS18,ELOVL4,PHLDB1,EXOC7,VAV2,MICAL1,SEMA3B" Drug 1239_UP LY 294002; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "APAF1,ZBTB10,WASF1,MYRF,IL33,SRSF11,NMT2,FADS2,WHRN,SLC4A7,AKAP12,DCAF8,SPOCK3,ING4,CORO2B,SEMA4D,ERAP1,MSL3,PRRC2B,STON1,HNMT,SCIN,MAPT,MGAT3,ZNF862,OCRL,GDPD2,RAB3IL1,BSDC1,ATXN1,FBXO11,SLC4A3,MAPK8IP3,ELOVL4,MCF2L,EXOC7,TCF7L2,TRIM2,SZT2,THRA,TRPC1,CLIP2,HPS4,PLSCR4" Drug 4019_DN Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "NME5,ADGRF5,ARRB2,MARK4,ALDH4A1,LARGE1,FOXN3,CHI3L2,CHN2,ARHGAP22,CSF1,ATN1,COQ7,FOXG1,AFF2,GBX2,GCNT2,SRCAP,GFER,USP19,ZNF276,MSL3,GRM8,ITPKA,KPNA5,MAPT,MBD1,PDE4D,EPN1,RALGDS,ZFP30,NLGN1,SLC1A7,SHANK2,KDM4B,WDTC1,TNIK,TSNAXIP1,DDN,AHCYL2,NACC2,TK2,XRCC4,REEP1" Drug 7087_UP CAY10397; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "APLP1,ARRB2,ATM,CFLAR,ST3GAL5,SCAPER,WASF1,CLTB,FADS2,HOMER3,PICK1,PLEKHO1,FAM49B,GPER1,CACFD1,GRM1,SLC2A6,ITPKA,MIA2,TAGLN3,NDUFA5,NEK1,PFKFB2,PLCD1,ZNF426,CNNM2,SAMD9,PTHLH,PTPRE,ARHGEF10L,NUDT11,ASRGL1,SUPT20H,ST6GAL1,BTBD7,INTS9,HECW1,COBL,KIAA0930,ARHGEF12,TMEM121,XRCC4,SNX27,RNF146" Drug 1505_DN Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "OGT,CDC14B,CDK13,ATM,STX16,BTRC,CAMK2G,SMG7,DTNA,FEM1B,PHF20L1,ZNF589,FER,FGFR1,FAM49B,CRCP,GLYR1,RAB30,CACFD1,INPP5B,MAP4,NFYA,CNOT4,PDE3B,STRN3,POLG,MAPK8,APTX,ATG16L1,ARHGEF10L,ROM1,WDTC1,ZCCHC24,FNBP1,TSPYL2,POGZ,SEMA4A,PDLIM2,IQCE,TCF7,TRIM2,PSD3,KAT6B,ST7" Drug 7423_DN Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.41E-03 1.00E+00 3.65E-02 4.15E-01 44 195 "FAM131A,MADD,ASPH,EIF4G3,PLEKHB1,ZFYVE9,PDE4DIP,EDRF1,DCAF8,ZNF337,RIMS3,DBN1,SEZ6L2,RBM12,KAT8,ANKFY1,TRMO,CGREF1,SRCAP,GLS,GRB10,DIPK1A,MEIS2,SLC25A23,RETREG2,PRKAR1B,TMEM231,GTDC1,SH3BP2,EPN2,SLC15A2,ZKSCAN3,GLT8D1,ZBTB43,TSPYL2,MAPK8IP3,CEP68,NSFL1C,PLPPR2,VAV1,LMF1,SEMA3B,WIPF2,KAT6A" Drug CID000000051 alpha-ketoglutarate Stitch 7.41E-03 1.00E+00 3.66E-02 4.16E-01 55 254 "ABAT,SEMA6A,BBOX1,ASPH,ATP1A3,SLC25A14,KYAT1,CDO1,SLC22A6,CS,PHC2,AASS,PRKAG2,ATP5PD,TPK1,DOT1L,GAD1,GAD2,GATM,GCK,GPR162,GLS,GLUL,CBX1,GPT2,GPD1,GPD2,IDH3A,IDH3B,KCNK3,KHK,NPTX1,OGDH,PAH,PC,PKM,FTO,PSAT1,PRODH,APTX,RAB3A,TMLHE,OGDHL,KDM4B,KDM3A,CLSTN2,ADHFE1,JMJD6,SYT1,SLC19A3,TP53BP1,SLC13A3,ETNPPL,SLC17A7,JMJD1C" Drug CID000119192 SR 48692 Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "CCK,CCKBR,BOC,DNM1,DRD1,EDIL3,PPP1R1B,NUCB1,MAPK3,TAC3,NTSR2" Drug CID000656468 AC1LCV0V Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "ADAR,ADARB2,BRAP,GMPR2,FCGRT,AHCYL1,PYGM,NSD1,AHCYL2,RBFOX2,TUB" Drug CID000152917 imidazole-4-carboxamide Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "PDE8B,EARS2,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000051263 alfentanil Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "TRAPPC9,AASS,GPHN,ATP8A2,STON1,NBL1,OPRL1,CNTN3,ABCB1,PTN,ARX" Drug CID000461278 d4TMP Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "BCHE,KYAT1,ABCC5,DMTN,AGAP2,KCNMA1,POLG,DDN,TK2,TSC1,TSC2" Drug CID000005560 trichlormethiazide Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "SLC12A5,AGT,ATP1A1,CA4,CACNA2D1,SLC12A6,CALCRL,KCNMA1,NPPA,PCSK5,SLC12A4" Drug CID000005658 NSC93767 Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "ASIC1,CACNA2D1,CCK,ASIC3,CHRM1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B" Drug CID009549277 K00039 Stitch 7.44E-03 1.00E+00 3.66E-02 4.17E-01 11 32 "CALB1,MAG,MAPK3,MAPK8,MAPK9,MAPK10,MAPK12,SNAP25,SST,STX1A,ST8SIA2" Drug ctd:C024746 tobacco tar CTD 7.48E-03 1.00E+00 3.68E-02 4.19E-01 40 174 "KDM5D,INA,CD86,CRLF1,NIPBL,CNTN1,GDA,CNTNAP2,AIF1L,DMD,DTNA,ZNF585B,FECH,MEX3B,FOXF2,SEMA4D,DPYSL4,FYN,GLDC,GPR37,GSN,MAP2,SCAMP5,IDNK,NRCAM,PALM,SH3KBP1,VSTM2L,ZIK1,NEK11,MEG3,RTN1,NLGN4Y,NTNG1,EFHD1,UCHL1,ZIC2,TRIM9,TFIP11,VANGL2" Drug CID011963505 "5-Acetamido-5,6-Dihydro-4-Hydroxy-6-Isobutoxy-4h-Pyran-2-Carboxylic Acid" Stitch 7.59E-03 1.00E+00 3.74E-02 4.25E-01 20 73 "ACADM,DST,CNOT8,QKI,BOC,DCTN1,F8,ZMYND10,ST6GALNAC3,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,GRM3,KTN1,OPA1,PAH,TNIK,ACSBG1" Drug 6156_UP "(+,-)-Synephrine [94-07-5]; Up 200; 24uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "SYN3,ADCY2,BIN1,GAS7,RIPK1,MYRF,MAP7,CHRNB2,DNAJB5,PICK1,WHRN,CREM,CRYM,SIPA1L1,DCAF4,SV2B,EDNRA,EGFR,MBNL2,PLXNC1,RASGRP2,KAT8,BAIAP2,FOXG1,AGAP2,ZMYND11,ERAP1,SRCAP,PCSK1N,KCNK1,MX1,MYBPC1,NRCAM,CLDN11,PBX1,SSH1,PILRA,MASP1,ACSS3,CARF,SP4,SEPT8,DNAH7" Drug 2866_DN Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "EPB41L5,CDC14B,CDK10,ADAM15,BCL7A,TPP1,HOMER3,DAPK3,DBT,NR1D2,RCAN1,DTNA,HIPK3,FCF1,EIF4G1,SCML2,GALC,SPIN1,GLYR1,GPD2,GSN,AGFG1,LSS,KITLG,NEK1,NUMA1,SSH1,PIK3R1,PLXNB1,PEX5,ATG16L1,SEC14L1,PEX26,ZBTB43,SS18,ARHGEF9,WASHC4,AP4E1,KLC2,SF1,SNX27,EPM2A,RNF146" Drug 3733_DN 0179445-0000 [211246-22-9]; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "APP,MARK4,EIF4G3,SCAPER,C5,CFAP410,AP4M1,PLEKHB1,ARHGAP22,NRXN3,DNAJB5,SMARCAL1,CPS1,TENM4,HDAC9,HDAC4,RABGAP1L,EFNA3,PLEKHO1,DENND4A,KAT8,SORBS1,GLRB,GLS,MAPT,MX1,NEK1,PAK3,RETREG2,PPP5C,PRKAR1B,MAPK7,SH3TC2,MCMBP,ASAP3,SLC4A3,CEP68,COBL,TNS2,SMUG1,WIPF1,ZNF189,DPF3" Drug 4115_DN Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "AK2,ATM,ATP6V0A1,CFLAR,MAP7,NMT2,AKAP7,EDRF1,HP1BP3,RCAN1,SORBS3,VPS26C,ANKMY1,ANKFY1,GALC,GLYR1,RAB30,GLS,MAP4K5,HNMT,DHX35,KCNJ3,NFYA,CNOT4,NUMA1,LRP12,MAPK8,SAMD9,PTHLH,PTN,ITSN1,BTBD7,SLC20A2,TTC17,ZCCHC24,PSD3,TNS2,CRTC1,THRA,TMPO,ZIC1,ZNF24,WNK1" Drug 961_UP 5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "SLC12A5,ATP2B2,GYG2,BTRC,CLU,BAG4,GREB1,DOCK4,HDAC4,RASSF2,DBT,SPOCK3,EDN3,SIDT2,OPTN,EIF5,FAM198B,TUBB4A,CAMSAP1,SEMA4D,INPP5K,KCNMB4,KCNH2,MAOB,MITF,NF1,FSD1,MAPK8,PTCH1,RAB3IL1,RGS12,ROM1,TCP11L1,SH3BGR,PPM1E,ASAP3,SLC6A9,TSPYL2,STX1A,EXOC7,CRTC1,LAT2,MAP3K12" Drug 6807_DN Astemizole [68844-77-9]; Down 200; 8.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "ABHD6,GAS7,BMP7,BTRC,CACNA1D,CAMK2B,CAMK2G,KYAT1,LHX2,NMT2,RIMS2,PPP6R2,MFAP3L,SLC12A6,NCALD,ZNF589,FGFR1,FGFR3,DPYSL4,GLYR1,GPR19,GPR37,KCNH2,KCNJ3,TM6SF1,GIT1,PDE3B,PPP5C,PRKAR1B,LRRC49,GSTCD,FERMT1,SLC9A5,SHANK2,BTBD7,SNCA,SOX3,EMC1,PHLDB1,TMPO,CADM1,ZBTB14,PHTF2" Drug 2296_DN Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "AK2,SRPX,CDC42BPA,APOC1,ATM,STX16,SYNJ2,BTRC,SPAG9,QKI,BAG4,HP1BP3,DTNA,FCF1,APH1A,WAC,ZNF589,ANKFY1,ARFIP1,EML4,NR3C1,HSF2,IL6ST,MBNL1,MPP2,NFYA,SETD4,PIK3R1,PLEC,POLG,SYTL2,PEX26,PPP4R3A,FAM214B,ZBTB43,NXT2,SYT1,TRIM2,TMPO,ZNF24,SH3GLB2,EMSY,FXR1" Drug 6429_UP F0447-0125; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 7.62E-03 1.00E+00 3.75E-02 4.26E-01 43 190 "BIN1,CDC42BPA,PPFIA3,MARCH3,ARHGEF7,BAIAP3,CA12,CDH2,CLU,NMT2,CREM,CRY2,CSNK1E,TBC1D5,SMG7,DMTN,RRAGB,SORBS1,PRELID3A,FYN,ZNF276,MAP4K5,IL6ST,KIF5C,MBD1,MIA2,MMP16,NAP1L2,NFE2L2,ELOVL2,GAL3ST4,MYH14,HSPA4L,UNC5B,TSPYL2,SYT11,SATB2,HIRA,UBE2H,MPPE1,EPM2A,ST7,PHTF2" Drug CID000005032 1-ephedrine Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 17 59 "ACHE,ADCY2,ADRA1D,ADRA1B,ADRB2,PLA2G6,LGR5,SLC4A4,BLOC1S6,FLT1,MAG,MYL3,PENK,IFT122,SSTR2,RBFOX2,GJC2" Drug CID000182762 NSC 370147 Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,ABCB1,TUBB2A,TUBB1,TUBA1A" Drug CID013671153 CHEMBL35507 Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "APOC1,MTMR3,MTMR2,MTMR7,FCGRT,CELF1,PRKCG,RYR1,HPS4,FXR1" Drug CID000068258 5-hydroxytetralin Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "TAOK2,MEST,NDUFA5,CNTN3,PAX6,PDCD2,PRPSAP2,SAFB,TEK,RASD2" Drug CID004481261 AC1NAQXP Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "LGR5,CANX,AIFM1,PLEKHM1,CHRDL1,CASP8AP2,CD200,RPE,SLC6A8,SPX" Drug CID000118078 NSC72302 Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "TUBD1,SPEG,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000009801 prenylamine Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "ALDH7A1,CACNA2D1,CALM1,KRIT1,CS,CALN1,MYLK2,ABCB1,CABIN1,NUP214" Drug CID000010783 chlormethiazole Stitch 7.81E-03 1.00E+00 3.84E-02 4.37E-01 10 28 "SMC2,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,GRIN2C,GRIN2D,GLDN" Drug ctd:D004280 Dobutamine CTD 7.83E-03 1.00E+00 3.85E-02 4.38E-01 21 78 "ADCY6,ADRB2,ARRB1,ARRB2,CLU,CREM,DMD,EGFR,F3,GK,GNAS,IGF1,KCNH2,KCNJ11,NOS1,MAPK3,MAPK9,PYGM,SPTAN1,TAC1,TACR1" Drug CID000019190 Foxgreen Stitch 7.83E-03 1.00E+00 3.85E-02 4.38E-01 21 78 "BCHE,CDK5R1,CX3CR1,TUBB3,EFEMP1,SCARA3,FLT1,GNAS,GPT2,KCNMA1,KITLG,NF1,OMG,GSTCD,ROM1,SLC12A4,SPP1,SST,SSTR2,TMEM121,THRA" Drug CID000004499 nisoldipine Stitch 7.83E-03 1.00E+00 3.85E-02 4.38E-01 21 78 "AGT,CACNA1I,CACNA1G,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNA2D1,CACNB2,CACNB4,CACNG1,CACNA2D2,EDN1,CACNG7,CACNG3,CACNG2,NPY,PKD1,RYR1,RYR3,TPCN2" Drug CID000021701 Peptavlon Stitch 7.83E-03 1.00E+00 3.85E-02 4.38E-01 21 78 "ADCY2,ADCY5,ADCY6,ADCY8,APOC2,BBS2,CCK,CCKBR,CHGA,EDN3,EDNRB,GFRA1,MCHR1,HRH3,HNMT,RET,SST,SSTR1,SSTR2,TRH,NLRP3" Drug CID011987863 mu-I Stitch 7.83E-03 1.00E+00 3.85E-02 4.38E-01 21 78 "SERPINA3,ACHE,APLP1,APOC1,BCHE,RUNX1T1,CLU,VAX2,CNR1,CX3CR1,HMX1,MAPT,NOVA2,PKD1,MAPK9,SYP,TPM1,TRH,TTPA,ZIC1,NETO1" Drug 6973_UP 17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.83E-03 1.00E+00 3.85E-02 4.38E-01 42 185 "MRTFA,BIN1,DNAH17,KYAT1,DNAJB5,CRY2,ARHGEF10,EDRF1,EIF4G2,LRRC23,ANKFY1,FYN,B4GALNT1,LYVE1,COPS8,DIDO1,SPACA9,GRM8,MAP4K5,IGF1,MAP4,MAPT,MBD1,MYH3,NAP1L2,NPR2,KLK6,HSPA4L,SGK1,SH3BGR,ITSN1,PPM1E,FRMPD1,SYBU,PEX26,UNC5B,SYT1,ZEB1,PCDHGA10,FAM155A,SSPN,FXR1" Drug 831_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 7.83E-03 1.00E+00 3.85E-02 4.38E-01 42 185 "NDRG2,OSBPL1A,CFLAR,ST3GAL5,ARHGEF2,MAGI1,CLGN,CREM,SIPA1L1,CTH,EDRF1,ZNF337,DNAJC6,MFAP3L,MBNL2,ARMCX1,FAM49B,ATP2C1,CNTRL,GRB10,ADAMTS8,GRM8,FICD,INPP1,AFDN,NUCB1,MORC4,RPS6KA2,ATXN1,HSPA4L,SH3BGR,PPM1E,FNDC3A,NLGN1,ERC1,TSPYL2,LHPP,PLCB1,BEX4,PARD3,ZMYND8,VLDLR" Drug 4168_UP Sanguinarine [2447-54-3]; Up 200; 12uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 7.83E-03 1.00E+00 3.85E-02 4.38E-01 42 185 "DPF1,SYN3,ALK,GAS7,SPTBN4,N4BP2L1,CACNA1G,CHI3L2,TPP1,CNN3,AKAP7,FAM149A,ARHGEF10,RASGRP2,OGA,FYB1,DISC1,GNAL,GRK4,GRIK1,GRM8,WIF1,IRAK3,HLF,KCNMA1,MID1,MOBP,PAX6,ZNF426,ELOVL2,SCN2B,TRA2B,SLA,SOX10,IZUMO4,SPART,EPB41L3,JMJD6,TCF4,RIMBP2,WIPF1,ZNF711" Drug 6190_UP 15d-PGJ2; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 7.85E-03 1.00E+00 3.86E-02 4.39E-01 38 164 "BIN1,PRX,PDE8B,CD38,CHN2,CREM,MICAL2,CSNK1E,SIPA1L1,PDE4DIP,DOCK4,DGKG,KLHL3,SMG7,SV2B,FAM13A,MBNL2,BSCL2,PRKAG2,B4GALNT1,ALDH1L1,RAB30,STON1,GUCY1A2,KCNN1,VWA5A,NPPA,LRP12,SEPT4,TMEM255A,TTLL7,SYNDIG1,PALLD,CDK19,NSFL1C,POPDC3,TRIM2,ZBTB38" Drug CID000064727 lovastatin acid Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "ABCG2,HMGCR,NBL1,ABCB1,PIK3C2A,SLCO1A2,SYNE2,NETO1" Drug CID004229818 AC1N65YL Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "WDR20,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,HTR5A" Drug CID000656933 di-Z Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "SLC32A1,STX2,INPP5K,GLRB,GRIK1,SLC6A1,SLC6A11,DDN" Drug CID000006911 "2,6-Di-tert-butyl-4-(methoxy-meth-yl)phenol" Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "KIDINS220,DBT,PLEKHM1,DTNA,DMTN,PLP1,PBRM1,ICAM5" Drug CID016040294 G-V-D Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "PLA2G6,ZFYVE9,AFF2,NELFCD,PLP1,PMP2,CABIN1,ZIC3" Drug CID006336689 Tytin Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "CLTC,ARHGAP32,AASS,ITGAV,MYL3,SHANK2,ABCC8,PMEPA1" Drug CID000005688 AC1L1KWW Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "CCKBR,CHRM1,DRD1,B3GAT1,GFAP,TAC1,TAC3,TACR1" Drug CID000657073 thiocoumarin Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "ACHE,TBPL1,CST3,BOC,FCGR3A,GAA,MTR,SLC6A7" Drug CID000124247 "2',6'-dimethyltyrosine" Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "ARNTL,DMTN,HNMT,SLC11A2,OPRL1,PDYN,PENK,SLC15A2" Drug CID000054778 magister Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "ACHE,BCHE,CNDP1,MBNL1,NBL1,PTK2,FUZ,TMEM132D" Drug CID000697993 2-mercaptobenzothiazole Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "CBS,KYAT1,CD86,SIRPA,DNER,SLC14A1,CLSTN2,TAC1" Drug CID004469991 AC1NBLOD Stitch 7.88E-03 1.00E+00 3.87E-02 4.40E-01 8 20 "APPL1,GAD1,GAD2,CIT,DDX19B,GPSM2,PTPRN,PTPRN2" Drug CID000026596 parbendazole Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000165441 NSC-36768 Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000160565 DITPA Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "MED12,BRD8,KCNA4,KCND2,KCND3,MYH6,RET,TEK,THRA" Drug CID000068555 ibopamine Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "ADRA1D,ADRA1B,ADRB2,AGT,DDO,DRD1,NPPA,PDE3A,PDE3B" Drug CID000054897 alpidem Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "CBR1,DBI,GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2,ZEB1" Drug CID000030830 melarsen oxide Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "SLC29A4,GPD1,GPD2,PC,PFKFB2,PFKFB3,PFKFB4,PKM,NUP214" Drug CID000120712 colchicide Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID011589428 SureCN4397131 Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "APP,TUBB4A,ZMYND10,NEFH,NPY,PDE3A,PDE3B,SERPINI1,SLC14A1" Drug CID000000777 hydroxymethylpyrimidine Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "ABAT,PDXK,ARSE,CFLAR,NELFCD,TPK1,GART,GLUL,PLP1" Drug CID000028240 ICR-191 Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "ERCC2,FCGRT,NR3C1,JAK1,PEX2,PEX5,SMTN,SLC14A1,TK2" Drug CID000001328 DEPX Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,ALDH7A1,RNH1,SST" Drug CID000014995 deacetamidocolchicine Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000163705 AC1L4TG7 Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug CID000330401 7-epi-cephalomannine Stitch 8.00E-03 1.00E+00 3.92E-02 4.46E-01 9 24 "TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,INPP1,TUBB2B,TUBB1,TUBA1A" Drug ctd:D016589 Astemizole CTD 8.01E-03 1.00E+00 3.92E-02 4.46E-01 22 83 "MTUS1,CAMK2D,OSBPL3,VCAN,IGSF6,TLR7,PCDH17,GPM6B,IGF1,KCNH1,KCNH2,KCNQ2,KCNQ3,MAPT,MYH6,NDUFS7,PYGM,S100B,NECAB1,TF,TMOD1,FAM124A" Drug 1065_UP LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.04E-03 1.00E+00 3.94E-02 4.48E-01 41 180 "OSBPL1A,OGT,APBB2,CDK10,ALDH4A1,CBFA2T2,TPP1,LETMD1,ARHGAP32,GIT2,DMTF1,ACOT8,MBNL2,ING4,CDKL3,KAT8,OGA,INPP5K,BRD8,GLYR1,STON1,MDM4,MXI1,ZNF862,NUMA1,PPM1B,ZSCAN32,ARID4A,BSDC1,PCMTD2,PAQR6,ATXN1,FNDC3A,KDM4B,KDM3A,SPTAN1,CDK19,CEP68,TST,UBE2H,MARCH8" Drug CID000446871 AC1L9K70 Stitch 8.06E-03 1.00E+00 3.95E-02 4.49E-01 50 228 "APBA2,NCOA1,NIPBL,TBPL1,HDAC9,GSDME,MED12,ATN1,TOM1,EBF1,OPTN,TBR1,GPR162,AHDC1,BRD8,GPD2,NR3C1,PTPN5,HMGB1,HP,HPR,HSF2,HSP90AA1,IRF8,IFI16,DDX25,PBX1,PPARA,MED1,PROX1,RAD52,RASGRF1,RFX4,RFX5,GSTCD,RXRA,RXRG,SAFB,CHD9,SOX2,ARHGAP26,CLSTN2,SAMSN1,SST,DICER1,THRA,TMEFF2,ZBTB14,ZNF45,ZBTB16" Drug ctd:D003620 Dantrolene CTD 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "CAPN3,ABCG2,EDN1,GFAP,IGF1,KCNH2,KCNJ11,MEF2C,MYH7,NEFM,NPPA,RYR1,RYR3" Drug CID000009238 adamantane Stitch 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "CTNND1,FOLH1,NEU3,GRIA1,GRIA2,GRIA4,GRIN2C,GRIN2D,GRM3,P2RX7,MED1,NEU4,TNS1" Drug CID000166290 Antibiotic Ps 6 Stitch 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "EIF4G3,CA12,CBFA2T2,EIF4G2,INPP5K,GRM1,GRM2,GRM5,GRM8,MAG,DDN,TSC1,TSC2" Drug CID000449524 IN-1 Stitch 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "GAL3ST1,EN2,STX2,RTN3,FGF1,MAG,MBP,MOBP,MOG,OMG,RTN1,TNR,RTN4" Drug CID000445446 mM Q Stitch 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "ARNTL,CACNA2D1,CRY2,DRD1,EDNRA,IL6ST,KCNH1,KCNH2,LIFR,OXTR,MAPK9,SST,TRH" Drug CID000003448 gaboxadol Stitch 8.09E-03 1.00E+00 3.95E-02 4.49E-01 13 41 "SLC12A5,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,KCNK3,SLC6A1,SLC14A1" Drug CID004345957 Neuromedin B Stitch 8.13E-03 1.00E+00 3.95E-02 4.49E-01 15 50 "CCKBR,TPP1,GAD1,NR3C1,ASPRV1,NPY,PCSK2,MBOAT7,SCG5,SST,TAC1,TAC3,TRH,MKRN3,PLD4" Drug CID000026010 GaCl3 Stitch 8.13E-03 1.00E+00 3.95E-02 4.49E-01 15 50 "TUBD1,TUBB3,TUBB4A,TUBA8,GPR162,TUBA1C,TUBB2B,ITIH2,NEUROD1,PMP2,TF,TUBB2A,TUBB1,TUBA1A,GAN" Drug CID000001324 "(S)-1,2-Diolein" Stitch 8.13E-03 1.00E+00 3.95E-02 4.49E-01 15 50 "ABHD6,DGKZ,GPAM,DGKD,DGKI,DGKB,DGKG,GNE,DTNB,GAP43,GK,MBP,NRGN,PRKCB,PRKCG" Drug CID000001224 AC1Q7BEJ Stitch 8.13E-03 1.00E+00 3.95E-02 4.49E-01 15 50 "ADCY5,ADCY6,ADCY8,ADRA1B,CHRM1,HDAC4,DRD1,PNMA2,HTR2A,NUCB1,PSMA6,MAPK12,MLST8,TRH,NELFE" Drug CID000004127 flurbiprofen methyl ester Stitch 8.13E-03 1.00E+00 3.95E-02 4.49E-01 15 50 "PDXK,CD86,PCYT1B,CHRDL1,EBF1,AASS,EPB41,STX2,FCGR1A,FCGR3A,MX1,NCAM1,NHLH1,PDYN,TCEA1" Drug 1851_DN Hydroflumethiazide [135-09-1]; Down 200; 12uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "PPFIA1,CFLAR,MTMR2,CAPN3,CAST,MAP7,HOMER3,C2CD2,ZFYVE16,TBC1D5,KIAA0586,SLC12A6,RCAN1,IRAK4,BSCL2,CINP,CELF1,HBS1L,HTATSF1,MUM1,ITGAM,KTN1,MDM4,NAP1L1,CNOT4,RETREG2,POLG,MAPK3,DEF8,GON4L,RIC8B,ITSN1,FERMT1,FBXO11,DHX30,SLC11A1,ZCCHC24,ZNF302,MAPK8IP3,KLHL7,VPS13A,PJA1,XRCC4,NLRP3" Drug 2438_DN Pilocarpine nitrate [148-72-1]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ARID1A,KIDINS220,MTUS1,BCAR3,AMH,APAF1,APP,SLC4A4,CACNA1A,SCARB1,PLAA,COL9A2,CRY2,ZNF337,RCAN1,CNNM1,EFNB3,FAM13A,RASGRP2,CAMSAP1,FOXG1,POLL,TJAP1,N6AMT1,NF1,NPR2,OLR1,MAPK3,MAPK10,CNNM2,ZNF493,ZDHHC14,RGS10,MRAS,SLC1A7,PEX26,KAZN,TCF7L2,ZEB1,TPD52,FLRT2,XRCC4,GDPD5,UBE3B" Drug 5307_UP Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ASPHD1,KCNAB2,APP,ASPH,ATM,RIPK1,CFLAR,ST3GAL5,BTRC,HIP1R,KYAT1,ENTPD6,ADGRG1,FAM189A2,CRY2,EFNA3,EGFR,PLEKHO1,F3,PRKAG2,TRAF3IP2,GLYR1,ATXN2L,HMGCR,LSS,GIT1,PLEC,SMOX,MAPK3,MAPK7,PTPRE,RAB3IL1,TCP11L1,ST6GAL1,SYBU,ZNF365,SPART,NXT2,FCHO1,TRIM2,PSD3,PCDHA6,SEMA3B,MPPE1" Drug 5942_DN LY294002; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AK2,MARK4,ASPH,ALDH7A1,ADGRB2,NRP2,FUBP1,SH2B1,CRY2,OSBPL3,CNTNAP2,SIRPA,KBTBD11,RBM12,EIF4G1,EN2,NOP56,GPR17,GPER1,CNTRL,HAS2,IFI16,KCNN1,MAPT,MDFI,SETD4,OXTR,PAK3,GPR85,RETREG1,ATG16L1,KIRREL1,FBXW7,SFPQ,HSPA4L,TMCC1,KDM4C,NXT2,DICER1,ZMYND8,NAV3,EPM2A,GJC2,ACTR3B" Drug 5593_DN rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ASPHD1,NDRG2,PLA2G6,C1QTNF3,DOC2A,APOC1,BCAS1,SLC4A4,SLC2A11,CDC42,CHM,QKI,CNTNAP2,SDC3,TBC1D5,STX2,KAT8,FOXG1,DPYSL4,TPK1,MALT1,TDRKH,KCNH2,MATK,ZNF862,NRGN,SERPINE2,SAMD9,RGS3,PPP1R9A,FAM214B,SLC6A8,SIRT2,TSPYL2,MAPK8IP3,RPGRIP1L,CRTC1,CABIN1,VGF,MICAL1,ZNF23,WNK1,WIPF2,RNF170" Drug 4494_DN Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NME5,C1QTNF1,ALAD,SEMA4G,MARK4,SCAPER,ARHGEF1,LY86,WHRN,HAPLN1,AATK,VCAN,PPP6R2,DAPK3,DTNA,TUBB4A,FGFR1,CINP,DENND2A,ZNF276,GPR19,GUCY1B1,INPP5B,KPNA5,MAPT,NDP,MAPK8,SAMD9,GAL3ST4,ITSN1,PPP4R3A,SHANK2,ELMO2,COA1,OGDHL,KDM4B,EMC1,ARHGAP26,ELOVL4,JMJD6,ZEB1,ZNF24,UPF3A,SEMA3B" Drug 6135_DN Repaglinide [135062-02-1]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADORA2A,APAF1,SYNJ1,MTMR3,C5,ZFYVE9,TPP1,PREPL,CTNND1,ZNF337,SMG7,RABGAP1L,ING4,FECH,ERAP1,INPP5K,LILRA2,VWA5A,ZNF862,NF1,SIDT1,SNRK,RAB3IL1,PAQR6,ATXN1,GALNT10,HSPA4L,PPP4R3A,KBTBD4,ZKSCAN3,DBNDD2,ZBTB43,MAPK8IP3,SEPT8,CEP68,TCF7,TRPS1,ZKSCAN5,VIPR2,EMSY,PRDM2,GDPD5,KCNAB1,UBE3B" Drug 3872_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AK2,APC,PPFIA3,CDK13,MARK4,ATM,SLC2A11,REPS2,CRY2,CSF1R,SIPA1L1,USP6NL,DRD1,TOM1,TNK2,ERCC2,KAT8,FHL1,FYN,GCNT2,SRCAP,GLYR1,STON1,GPER1,ATXN2L,MAOB,MMP17,NDUFA5,NF1,CNOT4,RAD52,TCP11L1,WLS,ANKRD6,SLC1A7,FAM214B,WDTC1,ARHGAP26,CLASP2,MAPK8IP3,PLCB1,IQCE,TMEM121,SLC44A1" Drug 4656_UP Dipyridamole [58-32-2]; Up 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADORA2A,GAS7,ARRB1,ASTN1,NOL4,ADGRB2,CA4,CACNA1D,CAMK2A,MAP7,CLTB,AKAP6,ABCG1,CSNK1E,DGKB,HS3ST2,EDN1,HEYL,SIGLEC8,ALDH1L1,RUNDC3A,GPR75,GPR22,GRM8,VWA5A,MAPT,MDM4,MT1M,NOVA1,PDE3B,PDGFRA,ENPP2,RETREG1,LRRN3,RYR1,SCN2B,SELL,DOCK10,SNCA,CAND2,ATP10B,MCF2L,ZNF34,TPM1" Drug 2856_DN Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ALAD,SCAPER,PLEKHB1,CNOT8,TAOK2,CREM,CRY2,PDE4DIP,EDRF1,KIAA0513,DLG3,EFNA3,VPS13B,DMTN,TESK2,KAT8,ZNF589,FOXG1,SRCAP,POLL,PCSK1N,DIDO1,NR3C1,MAP4,GIT1,NEK1,SLC11A2,FSD1,PTCH1,ATG16L1,RGS10,CCDC25,ITSN1,ZCCHC24,CDK19,TACC1,TCF7L2,AP4E1,SLC44A1,RBFOX2,CDK20,PLPPR2,SYNC,RNF170" Drug 4426_UP 3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "KIDINS220,APAF1,APP,CDC14B,N4BP2L1,CFAP410,CACNA1D,CHM,MICAL2,CHD5,NOS1AP,DYRK1A,TNK2,ST3GAL6,ZNF589,FGF1,C1orf61,RASL10A,NEU3,ALDH1L1,GPM6B,AP4S1,HLF,SYNPO,LMO1,NEK1,PPP2R2B,PTAFR,RGS10,SEMA6D,ZFP2,ST6GAL1,KANSL3,BEX1,SPTB,AJAP1,PLCB1,SYT5,TMOD1,XRCC4,ZNF711,MVB12B,ADAMTSL3,AP3B2" Drug 3064_UP Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "SPARCL1,ATP2B2,BMP7,ABCG2,ATRNL1,INTS1,HEPH,ARNT2,TRAPPC9,DRD1,HEYL,FAM13A,EGFR,ERBB2,ABCA8,FGFR3,CHL1,GAD1,SIGLEC8,CSDC2,GUCY1A1,RASSF8,GPR45,HTR5A,SCIN,KCNJ5,MAPT,ADAM22,NPY,PMP2,ACSM5,RGS12,ZFHX4,SLC11A1,PALLD,ARHGAP26,TACR1,TBCEL,RIMBP2,TRO,KCNK12,SLC30A3,PMEPA1,SLC17A7" Drug 3248_DN Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "PLA2G6,FAM131A,APOC1,MPDZ,SYNJ2,SCAPER,B4GALT6,PLAA,EML1,ZNF589,DPYSL4,ATP2C1,TXNL4A,POLL,GPR37,TJAP1,ITPKB,IPO5,TM6SF1,NPTX1,SLC11A2,PDE3B,PLEC,PLXNB1,POLG,FAM184A,GTDC1,RGS10,RGS12,FOXRED2,SBF1,SH3BGR,SMTN,ZCCHC24,ZHX3,GLT8D1,TSPYL2,NSFL1C,MTCL1,ATP13A2,TIAM1,WIPF1,ZNF74,SEMA3B" Drug 1474_DN Pyrimethamine [58-14-0]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "DOC2A,MARCH3,CAPRIN2,CCNT1,SYNGR3,CREM,HINFP,ABCG1,DCAF8,DBT,HP1BP3,DNM2,DTNA,GNG4,INPP5B,MPP2,NF1,NFYA,OGDH,OGG1,PBX1,PCDH9,PDE4A,SLC25A23,TMEM104,WDR25,RAB3IL1,RGS10,ITSN1,FNDC3A,CCDC92,EPN2,TSPYL2,PLCB1,SEMA4A,EHBP1,TRIM2,AHCYL2,TRIO,HIRA,VAV2,EMSY,SEMA3B,NAV2" Drug 3429_DN Diethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADD3,ALCAM,KCNAB2,AP4M1,NCOR1,ABCG1,CTH,CTNND2,PPP6R2,GIT2,B3GAT3,DLG3,CDKL3,FER,EFCAB2,GLS,GPR37,HSD17B1,ITPKB,KCNJ3,MAP4,SCAMP5,ADAM22,LYRM9,ZNF862,NEK1,SNX10,RETREG2,PRPH,PTCH1,RIPOR1,FOXRED2,SBF1,CLSTN1,SLC20A2,CDK5RAP2,TTBK2,TCF7L2,SLC44A1,RBFOX2,REEP1,EVI5,GDPD5,KAT6A" Drug 6774_UP Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ACTN1,MRTFA,BIN1,APBA2,MARK4,ST3GAL5,CFAP410,HAP1,NFS1,CBFA2T2,CHRNB2,CLCN4,DNAJB5,NCOR2,CSF1R,PDE4DIP,DCAF4,EFNB3,LRRC23,ERCC2,TJAP1,KCNJ5,MMP16,MPP2,ZNF862,NPTX1,PIK3CD,PLCB2,MAPK7,PTAFR,C1orf54,SCN8A,CNKSR2,PEX26,SMARCD3,SNCA,MAPK8IP3,HIF3A,TGFBR3,ICAM5,TRIO,PLPPR2,NT5M,KAT6A" Drug 7393_DN Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "C1QTNF1,MPDZ,CFAP410,MAP7,FADS2,NIPBL,HOMER3,AKAP7,CSF1,ARHGEF4,PPP6R2,CDON,EPB41L1,STX2,INPP5K,MAN1B1,KLF12,HNMT,JAK2,KPNA5,LIG4,MAN2A2,GIT1,PAK3,PFKFB2,RC3H2,POLG,RAB3IL1,RGS10,DCUN1D2,PPP1R9A,KIF16B,EPN2,FAM214B,ZBTB43,CEP68,ANKRD12,KIAA1107,ARHGEF12,ZNF34,BHLHB9,LMF1,XRCC4,AAAS" Drug 5005_DN Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ABHD6,AK2,C1QTNF3,ARRB2,CAPRIN2,ASPH,BCL2L2,RCBTB2,NMT2,NECTIN3,EDRF1,INTS1,DMPK,TOM1,EFNA3,FER,BAIAP2,TPK1,GALC,SRCAP,GPR37,CNTRL,RASSF8,DHX35,MAP4,MEIS1,NPR2,NUMA1,PDE3B,RAB5B,ATG16L1,RNASEL,FOXRED2,ZNF821,KDM4B,SS18,FAM168A,EXOC7,IQCE,RPGRIP1L,TMOD1,CADM1,CLDND1,PCBP4" Drug 3471_DN Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ABHD6,NDRG3,AP1B1,ALCAM,CDC42BPA,FAM131A,BCAS1,ATM,CFLAR,KRIT1,HOMER3,CREM,CRY2,CTH,PPP6R2,EDRF1,HIPK3,TNK2,GPHN,SEMA4D,ANKFY1,GCNT2,GLYR1,NR3C1,HNMT,NF1,SETD4,PDE4A,SLC25A23,SMIM7,ZSCAN32,ZCWPW1,NEK11,LIMCH1,EMC1,SPART,TROVE2,CAMTA2,ELOVL4,SIN3B,TRPC1,ZMYND8,MAP3K12,MPPE1" Drug 5007_DN Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "APBA2,APP,CDC14B,PLA2G4C,ASPH,KRIT1,PLEKHB1,TBC1D5,RIMS3,DAPK3,DSCAM,DTNA,OPTN,RBM12,EGFR,ING4,EML1,TESK2,FGFR3,PRELID3A,SYT17,DISC1,MUM1,HSD17B1,IL6R,ZNF862,NUMA1,OGG1,OPA1,SLC25A23,PPP2R5C,MAPK12,CPEB3,CDK5RAP2,WDTC1,ZHX3,EXOC7,CRTC1,TMOD1,TRIO,ZNF45,HPS4,RNF170,SSPN" Drug 4292_DN 0179445-0000 [211246-22-9]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ABR,CDK13,NRP2,MYRF,BTRC,CAMK2G,WHRN,DCAF8,SMG7,ATN1,ABCC5,FAM13A,SUGP2,EN2,POLL,GPM6B,SHISAL1,SCIN,ITIH2,KIF5C,SMAD1,MPP2,PALM,SH3TC2,TTLL7,FBXW7,RPS6KA2,SBF1,ZNF667,KIF13A,SPTAN1,ZBTB43,LHPP,CEP68,STX1A,MGRN1,RPGRIP1L,SLC44A1,TK2,CABIN1,NDRG4,WNK1,PARP6,NAV3" Drug 1628_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "RBM10,ARID1A,BRAP,EP400,CDK10,ARRB2,NCOA1,MPDZ,BCL7A,CCNT1,SCARB1,MAP4K4,RAB26,ARHGAP32,G3BP2,MED12,TRAPPC9,SUGP2,FGFR1,EFCAB2,CRCP,MSL3,HTATSF1,PRRC2B,DIPK1A,ITPKB,KCNF1,MAP4,NFYA,NUCB1,SMIM7,DCUN1D2,ZNF331,FOXRED2,SUPT20H,ABLIM3,RAB3GAP1,SS18,TCF7L2,KAT6B,PLPPR2,LMF1,KLC2,TFIP11" Drug 3296_DN Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "KIDINS220,MRTFA,AMT,ALDH4A1,ARHGEF7,KYAT1,LARGE1,CACNA2D2,SOCS6,ZFYVE9,CREM,SH2B1,MFAP3L,PARD6A,KBTBD11,EFNB3,ANKMY1,FGFR3,MALT1,TXNL4A,NR3C1,HNMT,JAK2,NASP,NLE1,SLC25A23,LRP12,KLK6,SIDT1,GON4L,RAB3A,ROM1,RPS6KA2,ZNF365,PEX26,FAM214B,SPTAN1,TSPYL2,NXT2,CEP68,VGF,PRDM2,SEMA3B,ST7" Drug 1370_DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AP1B1,CDC42BPA,CNTNAP1,ATM,SLC25A14,TAOK2,ZFYVE9,PREPL,DAPK1,ACOT8,ABI2,C1orf61,GAA,TRAF3IP2,GRIK5,CACFD1,BTN2A1,NXPH3,KIF5A,SCAMP5,MPP2,NFYA,CLDN11,TMEM231,RAP1GAP,RFX5,MRPS18A,SH3BP2,SLC2A5,SLC11A1,SLC12A2,SLN,WDTC1,HECW1,ERC1,POGZ,NCDN,NSFL1C,TAC3,PDLIM2,AHCYL2,PARD3,CHST5,DPF3" Drug 1294_DN Hesperidin [520-26-3]; Down 200; 6.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AP2A2,SYNJ2,SCAPER,CAMK2G,CLCN3,TPP1,CSF1R,ZNF337,INTS1,DCTN1,C2CD2L,TNK2,RACK1,FCGRT,POMT1,TRAF3IP2,SEPT9,TXNL4A,CRCP,INPP5B,VWA5A,MAP4,MATK,SETD4,PTPA,TMEM231,RAB5B,RGS10,FBXW7,SIRT2,ZBTB43,FCHO1,NCDN,FAM168A,TCF4,TCF7L2,DICER1,SLC44A1,PARD3,WBP2,PLPPR2,WNK1,NT5M,WIPF2" Drug 2056_DN Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "RBM10,EP400,PPFIA3,FUBP1,CAMK2G,CNOT8,LHX2,ARHGEF6,NCOR1,OSBPL3,SNPH,RUSC2,C2CD2L,SMG7,PARD6A,SEZ6L2,LPAR6,ELAVL2,ECSIT,POLR1B,FAM49B,GNAS,AGBL5,SSH1,MBOAT7,MINDY2,PTPA,MAPK7,BCAS3,ATXN2,CASC3,SUPT20H,SLC1A3,DHX30,FNBP1,ZBTB43,DNMBP,WSCD1,SIN3B,ARHGEF12,LMF1,KLC2,NDRG4,ITM2C" Drug 2962_DN Spaglumic acid [4910-46-7]; Down 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AP2A2,CASK,ARRB1,SLC4A4,ATP6V0A1,BACH1,SYNJ2,SGCE,OSGIN2,CAMK2G,SLC16A4,CLGN,TPP1,C2CD2,CSF1,DBN1,RUSC2,DTNA,RBM12,FAM13A,ING4,CDKL3,ERAP1,DISC1,SRCAP,ADAM28,MX1,ZNF862,PTK2,PTPRO,RIPOR1,ZCWPW1,RET,ATXN1,PPM1E,AMBRA1,BTBD7,MAPKBP1,PALLD,TNIK,CAMSAP2,SMUG1,TRPS1,NT5M" Drug 2355_UP Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NDRG3,MRTFA,CASK,SYNJ2,ZFYVE9,ENTPD4,SIPA1L1,DAPK1,KIAA0753,HIPK3,CNNM1,SIDT2,COQ7,RASGRP2,ZNF589,PRKAG2,AFF2,GABRA4,HBS1L,NEU3,POLL,MAN1B1,INPP1,CNOT4,SLC11A2,NTRK2,PLTP,RC3H2,PPP2R5C,PPP5C,MAPK8,FBXW7,MRAS,FRMPD1,ARHGEF40,SLC11A1,SLC15A2,KDM4C,ZBTB43,ZC4H2,TMOD1,TPM2,VAV2,KCNAB1" Drug 6748_DN Bisoprolol fumarate; Down 200; 9uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "MRTFA,ARHGDIG,ATP1A3,ADAM23,BTRC,NRXN3,PLAA,IQCK,ARMC8,NCOR2,CNTNAP2,TOX,BRINP1,EXOG,SORBS3,MTSS1L,TRMO,SORBS1,TRAF3IP2,DISC1,GPM6B,ICA1,KIF5C,MEF2C,NEUROD1,NF1,NOVA1,GRAMD1C,SAMD9,ZSCAN32,RGS4,RGS10,RPS6KA2,TRAPPC13,FOXRED2,MYH15,WDTC1,DDN,PHLDB1,PCDHA5,CABIN1,TNS1,TRPC1,ZNF24" Drug 313_DN NU1025; Down 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AMPH,APBB1,KCNAB2,ADGRB2,BTRC,RUNX1T1,RAB33A,RAB28,ARHGEF6,KLHL3,AK5,DTNB,EDNRA,OPTN,AMOTL2,RASL10A,TRAF3IP2,PTPRT,VSIG4,KCNC1,KCNJ3,KIFC3,NOVA1,ELOVL2,PTPRD,RGS4,ANKRD6,SLC2A5,PPP4R3A,SLC8A1,SLC15A2,CDK5RAP2,SNCB,HECW1,PEG10,SPART,SSTR2,ZC4H2,ELOVL4,SYP,TEK,NPL,TMPRSS5,AMOT" Drug 6227_DN 2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ARID1A,ADRA1D,AP1B1,NCOA1,ATP2A2,SYNJ2,MTMR2,LARGE1,UBE2L6,NMT2,DCAF8,RABGAP1L,RCAN1,TSPAN5,FEM1B,PHF20L1,MRNIP,FHL1,SYT17,AHDC1,GHR,ARHGAP19,MAN2A2,MAP4,MAPT,GIT1,NFYA,SLC11A2,PDE4A,RAB3IL1,DCUN1D2,SUPT20H,ITSN1,SMARCC2,KDM4B,ZSWIM8,POGZ,ATP11A,TCF7,TRIM2,PARD3,RBFOX2,SSBP2,VAV1" Drug 5350_UP Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ARID1A,EPB41L5,DDO,MARK4,ATM,ALDH7A1,CFAP410,SCARB1,CNTNAP2,HDAC4,SRGAP3,RCAN1,EDN3,EPB41L1,NOP56,PDLIM5,PRELID3A,SRCAP,GFER,GRB10,CLASRP,KCNF1,KCNJ3,MAN2A2,MAP4,MINDY2,CEP97,GTDC1,RGS10,RGS12,ARHGEF10L,RPS6KA2,FOXRED2,SEC14L1,SMTN,SLC11A1,ZBTB43,NCDN,EXOC7,SMG6,PSD3,CABIN1,SEMA3B,UBE3B" Drug 1958_UP Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; PC3; HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NDRG3,GYG2,P2RX6,TBRG4,CNOT8,CLTB,ZNF337,DNM2,EPB41L2,ERCC2,GAA,DENND2A,GAD1,SEPT9,C1QL1,KCNMB4,PADI2,KLF12,SYNPO,MAP4,MPP2,MYT1,PBX1,KCTD15,PLCD1,MED1,PTAFR,RIPOR1,GAL3ST4,SBF1,SH3BP2,ZKSCAN3,CDK5RAP2,MAPKBP1,PHLDB1,GANAB,SEMA4A,WSCD1,NSD1,ARHGEF12,CLIP2,WNT7A,ZNF248,LAS1L" Drug 3892_DN Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NCOA1,MPDZ,CCNT1,CLGN,SOCS6,DNAJB5,AKAP7,NECTIN3,CREM,TOM1,ING4,CDKL3,EZH1,BAIAP2,IQCG,TPK1,CSPG5,MALT1,NR3C1,RNFT2,HSD17B1,IGSF1,LMO2,MAPT,PCDH9,PPM1B,RIPOR1,RAB3A,SEC61A2,TCP11L1,SBF1,NUBPL,SMTN,ZKSCAN3,ATP11A,KAZN,TRIM2,PSD3,TPM1,TRPC1,ZMYND8,MICAL1,GDPD5,MPPE1" Drug 5830_DN Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AP2A2,MTUS1,APC,ASPH,ATM,ADAM15,TAOK2,WHRN,SNPH,DCAF8,ZNF337,SPOCK2,SIRPA,SMG7,AK5,SGSM2,ACOT8,EDNRA,F3,DCTN2,FAM49B,RNFT2,SLC2A6,RASSF8,INPP5B,KHK,LRP12,PRPH,PAQR6,URGCP,SLC6A8,SMARCA4,SNCA,ZBTB43,DDN,ROBO3,TNS2,PARD3,CABIN1,HIRA,LMF1,ZNF23,MAP3K12,ST7" Drug 3049_DN Pentetic acid [67-43-6]; Down 200; 10.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "MTUS1,PLA2G6,APBB2,APOC1,HIP1R,LARGE1,CLGN,CLCN4,NMT2,PPP1R16B,DGKG,FAM13A,SORBS3,IRAK4,ELAVL3,MRNIP,DLC1,ZNF589,FHL1,GAB1,GABRA2,LILRA2,KCNJ5,LIG4,MAP4,MIA2,MID1,NOS1,CNOT4,OXTR,PDE4D,PILRA,FAM184A,RGS3,SCG5,CPEB3,IQSEC2,DMXL2,PSD3,AHCYL2,TEX15,ST7,PHTF2,SSPN" Drug 4834_DN Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADCY6,PPFIA3,SCARB1,PLEKHB1,FADS2,WHRN,DOCK4,GPRASP1,DCTN1,EIF4G1,SORBS3,ING4,KCNF1,KHK,MEIS1,ADAM22,NF1,NUCB1,TMEM104,TMEM231,RAD51D,RGS10,RNH1,SLC6A8,ZKSCAN3,SMARCA4,SS18,STX1A,ARHGEF9,ATP11A,KAZN,SEMA4A,IQCE,TRIM2,ARHGEF12,SLC44A1,VGF,NSD2,TFIP11,ZFAND5,PRDM2,GDPD5,URM1,PCBP4" Drug 1312_DN Thyroxine (L) [51-48-9]; Down 200; 5.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "BRAP,GRAMD1B,CDC42BPA,APAF1,APBB2,ARHGEF7,CAMK2G,AP4M1,ARHGAP33,TMEM184B,SIPA1L1,ZNF337,MAML1,SPATA2,PLXNC1,ERCC2,ANKMY1,FGFR1,CRCP,MUM1,IDH3A,MAP4,MEF2C,MIA2,OCRL,CDIP1,FAM184A,RGS3,RGS10,FAM214B,KDM4B,STX1A,MLC1,ARHGEF9,ATP11A,EXOC7,IQCE,NSD1,TNNT1,ZKSCAN5,PLPPR2,LAT2,NPDC1,ACTR3B" Drug 1379_DN Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ACTN1,ADD2,SEMA4G,ATM,N4BP2L1,ADAM15,KYAT1,CHRNB2,SUGP2,ABI2,TUBD1,TRMO,FAM49B,ATP6V1H,OGA,SESN1,PRRC2B,GRIK5,NAP1L1,NFYA,NRGN,OCRL,PKN2,DCUN1D2,MYH14,ATXN2,SFPQ,ITSN1,SLC11A1,ARFGAP1,SLN,CLUAP1,EMC1,UHRF1BP1L,POGZ,CEP68,DIP2A,ANKRD12,DMXL2,TCF7L2,SPX,CADM1,PRDM2,MPPE1" Drug 2437_DN Carbimazole [22232-54-8]; Down 200; 21.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "RALGAPA1,ARID1A,KIDINS220,APOC1,SYNJ2,CRY2,DGKG,RUSC2,RHOBTB1,CNNM1,EFNB3,LRRC23,RASGRP2,CAMSAP1,AGAP2,GAA,GABRA2,ALDH1L1,POLL,SPACA9,JAK2,VWA5A,MAP4,ZNF862,PDE4D,NLE1,PMP22,PILRA,RAD52,CARF,EMID1,MRAS,DZIP1,SLC6A8,SLC11A1,MYH15,TMCC1,KDM4B,JMJD6,TCF7,TCF7L2,SYNE1,OBSL1,PHTF2" Drug 7271_UP Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADCY6,KIDINS220,APOC1,APP,CDC14B,CFLAR,ARHGEF7,DZIP3,CTNND2,SMG7,CDON,DTNA,EGFR,BAIAP2,PRELID3A,FYN,GABRA2,ZNF274,NCKAP1,GLS,GUCY1A1,IL6ST,JAK2,KIF2A,KIF5C,AFF1,NUMA1,OCRL,REV3L,TTLL7,CLIP1,SLC14A1,SMARCD3,ARHGAP26,CEP68,SYT1,FBXW11,ZEB1,TRIM2,PARD3,TRIO,MICAL1,NSD2,PHTF2" Drug 1445_UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NDRG2,ADAR,BRAP,SYT13,ANK3,CNTNAP1,APBB1,MARK4,BMP7,BTRC,CA12,CAST,DNAJB5,AKAP7,CTH,DTNA,RASGRP2,PRKAG2,ARFGAP2,SRCAP,KCNMB4,GNG4,CACFD1,ATXN2L,KCNJ3,NTRK3,NUCB2,ENPP2,PLCD1,PLTP,C19orf57,ZNF671,TCP11L1,TMEM156,MAPKBP1,SPART,SYP,TCF4,TNS1,TPM3,VGF,SLC13A3,SMIM8,ZNF248" Drug 2888_DN Tetracaone hydrochloride [136-47-0]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NME5,AMPD3,AMT,SEMA4G,ASPH,CACNA1D,CAMK2B,ASIC3,SLIT2,ABI3BP,CNTNAP2,EDRF1,DCTN1,EXOG,SGK2,VPS13B,STX2,SCML2,FHL1,HBS1L,DISC1,TM6SF1,MMP16,ADAM22,NEK1,NTRK2,TNPO2,POLG,PRKAR1B,CNNM2,PLPPR1,RGS12,RYR1,PEX26,SMTN,CXXC4,WDTC1,PHLDB1,STX1A,TNS2,TIAM1,TK2,SPHK2,PRDM2" Drug 5806_DN Suxibuzone [27470-51-5]; Down 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "MTUS1,ANK3,CDC14B,ATM,NRG2,OSBPL3,SMG7,SIDT2,LPAR6,HSD17B14,PRKAG2,FHL1,PRRC2B,RASSF8,HNMT,IL6ST,INPP5B,MMP16,NFYA,PLCD1,LRP12,PTPA,SAMD9,ZNF331,SBF1,IL17RB,PPP1R9A,AMBRA1,ZKSCAN3,CDK5RAP2,ARHGAP26,ZBTB43,MAPK8IP3,EXOC7,SATB2,BHLHB9,RBFOX2,HIRA,UBTF,LMF1,XRCC4,ZNF24,PRDM2,VPS35L" Drug 1810_UP Sulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "OGT,ASPH,ZSCAN18,ATM,MPDZ,MTMR2,FOXN3,HOMER3,WHRN,NCOR1,PDE4DIP,DZIP3,FCF1,MBNL2,LPAR6,ING4,PLEKHO1,ETV1,FHL1,GART,GCNT2,EML4,PCLO,HNMT,JAK2,NFYA,KCTD15,CDIP1,SYTL2,SH3TC2,FAM192A,PPP4R3A,KDM4D,CCDC88A,SLC20A2,LMBRD1,SS18,NXT2,ATP11A,ZNF34,TPM1,NSD2,KCNAB1,RNF170" Drug 2372_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ASIC1,AP2A2,ALK,MRTFA,GAS7,STX16,ADAM15,LDLRAD4,QKI,IQCK,KIAA0753,E2F5,BSCL2,CD320,PRKAG2,CAP2,ANKFY1,ALDH1L1,SRCAP,ZNF276,NUDT21,NF1,CNOT4,PEX5,RAB3A,RAD51D,RALGDS,FAM184A,RAP1GAP,RGS10,TCP11L1,MAP6D1,PPP4R3A,ZKSCAN3,KIF1B,NXT2,MAPK8IP3,CAMSAP2,FBXW11,TCF7,KAT6B,RBFOX2,ZNF32,RNF146" Drug 6471_DN S-(+)-ibuprofen [51146-56-6]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "TRMT9B,AMPD3,EPB41L5,CDK10,CAPRIN2,ATM,CDH10,LHX2,ENTPD4,FAM169A,JAKMIP2,DLG3,EDNRA,SUGP2,DMTN,ANKMY1,FGFR1,FAM49B,OGA,FERMT2,IL6ST,ITPKB,VWA5A,MAPT,NF1,PDE4B,PIK3CD,FSD1,RGS10,RGS12,BCAN,SLC15A2,EFHD1,KDM4C,IQSEC2,TROVE2,CEP68,ASTN2,KIAA0930,PSD3,ZMYND8,REEP1,GDPD5,SEMA3B" Drug 7312_DN Pivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "APOC1,PPFIA3,BID,CAMK2G,KYAT1,BAG4,NRG2,ENTPD4,HINFP,DZIP3,GPRASP1,DBT,KLHL3,DNM2,AASS,KAT8,FGFR1,ANKFY1,TXNL4A,GPM6B,HMGCR,MBD1,NF1,SLC11A2,ODF2,OPA1,RAB3A,RAB3IL1,RAD51D,RGS3,RGS4,MAP6D1,CLIP1,SBF1,AMBRA1,SMARCD3,BEX1,CAMTA2,ELOVL4,SYNE2,VPS13A,TSN,MICAL1,PHTF2" Drug 3778_DN Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADCY6,ADD2,APOC1,NRP2,CHM,PLEKHB1,IQCK,WHRN,CREM,CNTNAP2,DCAF4,GPRASP1,ETV1,IQCG,ANKFY1,DCTN2,TRMO,ZMYND11,MSL3,BACH2,HSF2,LIFR,VWA5A,LRP12,GRAMD1C,SAMD9,WDR25,FAM120C,NEK11,FBXW7,ZNF671,ATXN7,NLGN1,RAB3GAP1,ARHGEF40,ZHX3,COLGALT2,COBL,SYNE1,GPR161,WIPF1,NSD2,ZBTB14,RNF146" Drug 4587_DN Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "PKP4,ALDH4A1,SLC4A4,ALDH7A1,CFAP410,CACNA1A,MAP7,PLEKHB1,AASS,MRNIP,EN2,STX2,SPEG,ETV1,EZH1,FGFR1,C1orf61,CINP,OGA,USP19,MSL3,GRK4,KLF12,HNMT,INPP5B,MAPT,MN1,MT1M,SLC11A2,PLXNB1,PROX1,PRPH,RAD52,CSRNP3,ASAP3,FAM214B,ZNF334,CRTC1,TPM2,OSBP2,VIPR2,XRCC4,MAP3K12,NT5M" Drug 3508_UP Risperidone [106266-06-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ACTN2,ADORA3,AK2,SYNJ1,MTMR3,CDO1,CACNA2D2,ENTPD4,CRMP1,SDC3,RASSF2,DAPK3,NCALD,ZNF589,FGFR1,SIGLEC8,INPP5K,MALT1,GLYR1,GPD2,GSN,KHK,LSS,SMAD1,ADAM22,NOS1,NECAB2,PACSIN1,GON4L,RAD52,SUSD4,KCTD17,RTN1,SELL,MRAS,SMTN,LIMCH1,ZC3H13,TROVE2,VAMP1,PLCB1,KAZN,EXOC7,TBCEL" Drug 917_UP quercetin dihydrate; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "PPFIA3,AQP4,MTMR3,BTRC,SRSF11,VAX2,DNAJB5,TENM4,PDE4DIP,ARHGEF4,CTNND2,G3BP2,RABGAP1L,TRAPPC9,DYRK1A,ERCC2,F3,KIAA1109,FGFR3,SIGLEC8,MSL3,IRAK3,HNMT,ADAM11,MMP16,NUMA1,PLTP,PPARA,ZSCAN2,KHDRBS2,TCP11L1,ZNF821,KANSL3,CXXC4,RCOR3,TSNAXIP1,INKA2,PLCB1,BEX4,TPM2,RUNDC3B,VAV2,XRCC4,ITM2C" Drug 6670_UP Brinzolamide [138890-62-7]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ACHE,SPARCL1,CDC42BPA,KCNAB2,LGR5,PPP4R4,BMPR1B,SYNJ1,FUBP1,HAP1,CAMK2B,CBFA2T2,CDH10,CRY2,CSF1,ATRNL1,NTM,DTNA,EFNB3,ETV1,BAIAP2,RUNDC3A,RND1,FERMT2,STMN2,HRH3,HSD17B1,KCND3,NOVA2,PDGFRA,GPR85,TNPO2,MAPK10,RNASEL,RASA3,DOCK10,SLC12A4,ZNF334,SNAP25,SNCA,MCF2L,CRTC1,ZKSCAN5,DPF3" Drug 1996_DN Minoxidil [38304-91-5]; Down 200; 19.2uM; HL60; HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NDRG2,OGT,APP,NUMB,ST3GAL5,PTBP2,CD38,CHRNB2,TAOK2,FADS2,QKI,TMEM184B,SLC4A7,HDAC9,DTNA,CEND1,ECSIT,SMC2,OGA,LILRA2,CACFD1,BTN2A1,GSTM5,MAN2A2,GIT1,NF1,SETD4,PLCB2,LRP12,PPP2R2B,NEK11,BCAN,SLC2A5,PEX26,SIRT2,ZKSCAN3,SS18,MPRIP,NSFL1C,ZEB1,KAT6B,CHST5,TFIP11,WIPF2" Drug 1841_DN Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "AK2,APC,ATM,CAPN3,RCBTB2,CNOT8,HOMER3,VCAN,GAPVD1,MED12,FRY,SUGP2,EPS8,FKTN,IP6K2,CINP,HBS1L,GART,ARFIP1,DIDO1,HSF2,MARK3,MIA2,SETD4,SNX10,RC3H2,LRP12,PPP5C,C1orf109,ZNF331,SH3BP2,DZIP1,GLT8D1,SPTAN1,ZNF302,LARP4,SS18,FAM168A,VPS13A,SIK3,TMPO,TPD52,UBTF,FIP1L1" Drug 6782_DN D-cycloserine [68-41-7]; Down 200; 39.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "APBB2,APC,ALDH4A1,BACH1,CFLAR,SYNJ2,FAM189A2,NIPBL,FEZ1,CSNK1E,USP6NL,GIT2,MFAP3L,DSCAM,SIDT2,ANKMY1,F8,BAIAP2,ATP2C1,GPR153,DISC1,MALT1,TXNL4A,HTATSF1,GPD2,BTN2A1,LYRM9,NF1,NFYA,CNOT4,FA2H,MINDY2,PRODH,TMEM104,PTCH1,ELOVL2,MAP6D1,ZHX3,TROVE2,KAZN,MCF2L,CDK20,XRCC4,SPHK2" Drug 7300_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADRB2,LGR5,CDK13,MYRF,HAPLN1,PLCH2,VCAN,CTIF,RUSC2,DRP2,SEMA3D,SIDT2,ING4,MTSS1L,ANKMY1,FDFT1,CSPG5,FYB1,ZNF44,GUCY1B1,KLF12,HTR5A,DIPK1A,VWA5A,PALM,CCSER2,MAPK8,WDR25,PTPRN2,C1orf54,TTLL7,NEK11,FAM214B,SHANK2,SNCA,ZHX3,DDN,MAPK8IP3,PLCB1,ARC,PCDHGA10,TIAM1,TK2,TRIO" Drug 627_UP monastrol; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADCY6,AZGP1,HIP1R,SYNGR3,ENTPD6,ARHGEF2,TBRG4,IQCK,SLC4A7,ABCG1,ACOT8,CD320,CAMSAP1,ATP2C1,OS9,GRB10,CACFD1,MAN2A2,MARK3,MSRA,THYN1,RETREG2,APTX,MRPS18A,SLC25A36,ATXN2,ATXN7,GALNT10,PPM1E,R3HDM2,SIRT2,HECW1,KIF1B,MAPK8IP3,PHLDB1,FBXW11,EHBP1,CRTC1,TNNT1,RBFOX2,GORASP1,PLPPR2,PMEPA1,PHTF2" Drug 507_DN SC-58125; Down 200; 10uM; SKMEL5; HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "DGKD,ALDH4A1,NRP2,SYNJ2,CA12,SLC25A14,SCARB1,CHN1,CLTB,NIPBL,WHRN,C2CD2L,ATN1,BSCL2,KAT8,FER,FYB1,NR3C1,ATXN2L,HMGB1,ITGA7,MEF2C,ADAM22,OCRL,PLEC,POLG,SLC6A15,FERMT1,CHD9,SMARCD3,MAPKBP1,PALLD,EMC1,CLASP2,POGZ,GSE1,KAZN,EXOC7,ATP13A2,TNNT1,GORASP1,NSD2,MPPE1,MVB12B" Drug 4728_DN Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ARHGDIG,CA4,ARHGEF1,SCARB1,MAGI1,RCBTB2,B4GALT6,PLAA,NMT2,WHRN,CSF1R,MFAP3L,SMG7,EDNRA,FCF1,EFNB3,STX2,PRKAG2,GLYR1,GPD2,EML4,MAP4K5,KCNF1,KITLG,NUMA1,PDE3B,STRN3,PRPH,FAM120C,AP1AR,ANKRD6,PEX26,BTBD7,SMARCD3,LIMCH1,WDTC1,PLCB1,PCDHA5,THRA,TMPO,TNS1,WNK1,MPPE1,TIGD6" Drug 2770_DN Berberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ABHD6,MRTFA,FAM131A,ARHGDIG,BTRC,CA12,CCNT1,FAM189A2,SLC4A7,EDRF1,COQ7,BAIAP2,HBS1L,ALDH1L1,HTATSF1,CACFD1,INPP5B,IPO5,MMP16,NRGN,PCDH9,PDE4A,SLC25A23,FSD1,MAPK7,RGS10,ARHGEF10L,TCP11L1,CCDC92,SLC6A8,SLC22A4,KDM4B,SOX3,CDK19,INKA2,ELOVL4,CEP68,STX1A,AP4E1,KLC2,KCNK12,GDPD5,MPPE1,GAN" Drug 503_UP "indomethacin, USP; Up 200; 100uM; SKMEL5; HG-U133A" Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ANK1,ASCL1,ASPH,BMPR1B,CBFA2T2,ADGRG1,CNOT8,SLIT2,CNTFR,NCOR2,PDE4DIP,RIMS2,ING4,RCAN2,GABRA4,STON1,ADAMTS13,PADI2,HMX1,KCNK3,MX1,NOS1,PLEC,PLXNB1,LRP12,MBOAT7,SH3TC2,RAP1GAP,RGS4,SYNDIG1,ITSN1,KIF16B,ANKRD6,EFHD1,IGSF9B,NMNAT2,TEX2,SPTB,CDK19,SSTR2,SLC13A3,FIP1L1,MVB12B,JMJD1C" Drug 2648_DN Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "NDRG2,ADCY6,APP,CFLAR,PLEKHB1,ZFYVE9,PLAA,HOMER3,AKAP7,SDC3,DAPK3,LYPD1,EFNA3,VPS26C,F3,KAT8,FHL1,FAM49B,DISC1,TXNL4A,MSL3,POLL,TDRKH,GRIK5,ARHGAP19,HNMT,SLC11A2,PLXNB1,RAD52,GTDC1,RGS3,RPS6KA2,FOXRED2,SBF1,ZNF821,BTBD7,CDK19,STX1A,ASTN2,ATP11A,ZBTB14,GDPD5,SSPN,RNF146" Drug 4427_DN haloperidol; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ST3GAL5,ARHGAP33,ADGRG1,CNTN1,ARHGEF4,MFAP3L,G3BP2,DMPK,RCAN1,HIPK3,EFNB3,AASS,ING4,SEMA4D,ZMYND11,ICA1,SCIN,LAMA2,MDFI,MDM4,MMP16,LYRM9,NDUFA5,NOS1,CNOT4,NRCAM,NTRK2,PENK,RAB3IL1,FAM184A,RGS4,RGS10,RGS12,KCTD17,DDN,MAPK8IP3,SEMA4A,ZEB1,TIMP4,RUNDC3B,TRPC1,XRCC4,WNK1,PHTF2" Drug 6740_UP Cyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "ADGRF5,ADGRB2,MTMR3,CACNA1D,MTMR7,LARGE1,CHRNA4,CABP1,CSF1,CSF1R,RIMS2,CTIF,C2CD2L,DSCAM,AGAP2,GABRA5,GATM,RUNDC3A,GNAL,GNG3,STMN2,GPR45,ELOVL5,HPCA,IL6R,KCNJ9,DDX25,P2RY1,TREM2,GPR85,CCDC40,KCTD17,MRAS,RASA3,ZFP30,SLC6A9,FAIM2,IQSEC2,ATP10B,SYT1,TAC3,TACR1,UBE3A,AMOT" Drug 7297_DN Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "FAM131A,ASPH,KYAT1,RCBTB2,LHX2,KIAA1549L,ENTPD4,CTH,FAM131B,LYPD1,TRAPPC9,DYNC1I1,TUBD1,FGF13,CINP,SEPT9,GCNT2,SRCAP,CRCP,CNTRL,NR3C1,CLASRP,MAP4K5,HNMT,IL6ST,JAK2,SETD4,PC,PLCD1,SMIM7,MAPK12,FAM214B,BTBD7,SLC22A4,SMARCD3,CDK19,ELOVL4,HIRA,NSD2,SH3GLB2,UPF3A,EVI5,MPPE1,ST7" Drug 2751_DN Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "APOC1,PPFIA3,CDC14B,CFLAR,BMP7,BTRC,KRIT1,CNOT8,SLC4A8,NCOR1,PARD6A,DTNA,EFNA3,NCALD,F8,ZNF589,TRAF3IP2,SYT17,DIDO1,HSD17B1,ITPKB,MAPT,ZNF862,NEK1,PDE3B,PEX5,RAD51D,ATG16L1,BSDC1,DPF2,SBF1,CCDC92,SCMH1,BTBD7,ZCCHC24,SP2,ZSWIM8,ATP11A,EXOC7,PLPPR2,VGF,LMF1,WNK1,SEMA3B" Drug 6745_DN Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "OGT,KIF1A,ADAM23,MTMR3,CANX,CHM,B4GALT6,RAB28,CPS1,SLITRK5,ARHGEF4,DLG3,ST8SIA3,EPB41L2,MTSS1L,IQCG,TDRKH,HSF2,IL6ST,KHK,MIA2,CNOT4,SLC11A2,PLCD1,ZSCAN32,RAB5B,RALGDS,ZCWPW1,AMBRA1,CCDC88A,EMC1,ARHGAP26,SPTAN1,SS18,STX1A,PLCB1,KAZN,TNS1,TRIO,TRPC1,ZNF45,EVI5,MPPE1,PHTF2" Drug 6309_DN Oxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.13E-03 1.00E+00 3.95E-02 4.49E-01 44 196 "MTUS1,BIN1,AMT,CNTNAP1,APC,CFLAR,SCAPER,CLU,RIMS3,C2CD2L,SIDT2,OPTN,FAM13A,CDKL3,VPS26C,BAIAP2,CINP,B4GALNT1,SRCAP,PRRC2B,KCNMA1,KIF5C,MAN2A2,MAPT,ZNF862,ZNF426,PTPA,PPP5C,MAPK7,BEND5,GAL3ST4,LIMS2,KDM4D,SHANK2,CDK5RAP2,BEX1,ELOVL4,GSE1,TCF4,SYNE1,ZKSCAN5,TFIP11,UPF3A,KAT6A" Drug CID000071191 cromakalim Stitch 8.14E-03 1.00E+00 3.96E-02 4.50E-01 23 88 "AGT,ALDH7A1,CACNA2D1,CHRM1,ABCC9,EDN1,EDN3,EDNRA,CRCP,KCNMB4,GUCY1A2,GUCY1B1,KCNJ3,KCNJ4,KCNJ5,KCNJ9,KCNJ10,KCNK3,KCNMA1,NOS1,NPR2,ABCC8,TAC1" Drug CID000005411 tetracaine Stitch 8.14E-03 1.00E+00 3.96E-02 4.50E-01 23 88 "ACHE,ADCY2,ADCY5,ADCY6,ADCY8,CD38,ASIC3,CHN1,CHRNA4,CHRNB2,KCNK1,KCNK10,PRKCB,PRKCG,PKN2,PRKCZ,QDPR,RYR1,RYR3,SCN4B,SCN3B,TAC1,ZIC3" Drug ctd:D016685 Mitomycin CTD 8.15E-03 1.00E+00 3.96E-02 4.50E-01 83 410 "ALCAM,APAF1,APP,PDXK,IGDCC4,ARNTL,ATP1A1,BLM,DDR1,MAP7,PRC1,ZBED1,CLGN,ADGRG1,LHX2,NMT2,DNAJB5,COL9A3,CPS1,AKAP12,ATRNL1,ERC2,DCAF4,HDAC9,DAPK1,DCT,ZBTB24,DMD,FIS1,BSCL2,EFS,FDFT1,FHL1,SORBS1,FYN,DKK3,AHCYL1,ZMYND11,DBF4,NR3C1,ARHGAP19,IL6R,L1CAM,MATN2,MBP,BLOC1S2,MX1,NFYA,ABCB1,GPSM2,PLP1,PMP22,PPP2R5C,PPP2R5E,PKIA,PRKCZ,MAPK3,MAPK8,ZDHHC14,RTKN,TMEM156,ATXN1,SGK1,SCG5,SYBU,ZNF365,LIMCH1,RBM34,INKA2,KANK1,PRRC2C,DNAJC9,COBL,KAZN,TRIM2,OBSL1,HEY1,TPD52,UCHL1,XRCC4,ZNF45,ST7,JMJD1C" Drug CID000000174 polyethylene glycol Stitch 8.23E-03 1.00E+00 4.00E-02 4.55E-01 63 299 "SERPINA3,SYN3,ABHD6,AMT,AZGP1,BARD1,NRP2,MTMR2,CACNA1A,CALM1,RUNX1T1,CDO1,CFL2,SOCS6,TPP1,CP,CSNK1G3,RIMS2,BOC,DAPK3,ENO2,SPEG,F5,F8,ACTL6B,PDLIM5,ACSS1,NEU3,CYP46A1,GFRA1,GLS,POLL,LNX1,GPD2,CLASRP,ACOT7,RBPJ,KCNH1,MAG,MEST,MTTP,OLR1,PDE4D,ABCB1,EPN1,PRKCG,MAPK10,GDPD1,PTPRB,PTPRG,PEX5,RNASE1,PBRM1,RYR1,ASRGL1,PEG10,ADHFE1,SYN2,TMEM121,ACTR6,ETNPPL,TRIM9,CAMK1G" Drug CID000008405 isoquinolinium Stitch 8.23E-03 1.00E+00 4.00E-02 4.55E-01 24 93 "ADORA3,ALDH7A1,CBR1,KRIT1,LRBA,CDC25B,SLC22A6,LY86,ARHGAP32,DBI,DRD1,PNMA2,ATP8A2,TNFAIP8L3,MAOB,NPY,OGDH,P2RX7,PIK3CD,PRKACB,PKIA,PRKCB,PRKCG,SARS" Drug CID000030318 osmium tetroxide Stitch 8.25E-03 1.00E+00 4.01E-02 4.56E-01 18 64 "API5,CACNA1A,ENTPD4,ATN1,DYRK1A,MAG,MID1,OGG1,PC,PPP2R2B,MAPK8,MAPK9,MAPK10,MARCH1,ATXN7,NEIL2,TTPA,PCDH15" Drug CID000469074 adenosine analog Stitch 8.25E-03 1.00E+00 4.01E-02 4.56E-01 18 64 "ADAR,ADARB2,ADCY5,ADCY6,ADCY8,BRAP,ADORA1,ADORA2A,ADORA3,CCNH,SLC29A4,PDE3A,PTPRB,RGS4,RNH1,TRIO,TUB,UBTF" Drug CID000079723 PIPES Stitch 8.25E-03 1.00E+00 4.01E-02 4.56E-01 18 64 "NT5C3B,PNKD,DBT,DNAH9,PHC2,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,MAP2,RAD51D,FAIM2,TUBB2A,TUBB1,MFF,TUBA1A" Drug 1006_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 8.26E-03 1.00E+00 4.01E-02 4.56E-01 40 175 "OSBPL1A,PPFIA3,CFLAR,ST3GAL5,CAMK2G,CRLF1,PDE4DIP,FAM169A,EDRF1,GIT2,MFAP3L,RCAN1,DTNA,DPYSL4,B4GALNT1,DIDO1,NR3C1,ATXN2L,HSD17B1,LYRM9,NACA,NAP1L2,MBOAT7,PRKCZ,KLK6,MORC4,HSPA4L,SH3BGR,PPM1E,ZCCHC24,TSNAXIP1,TSPYL2,JMJD6,POPDC3,DMXL2,TRIM2,AHCYL2,ZMYND8,DNAJC12,FXR1" Drug ctd:D017974 Uranium Compounds CTD 8.26E-03 1.00E+00 4.01E-02 4.56E-01 40 175 "SLC12A5,AMPH,ATP2B2,AZGP1,ADGRB3,NAE1,CANX,CCKBR,CHRNA4,CNTN1,FBXL5,FCGRT,SEC24B,OLFM1,FGF12,ATP6V1H,GLUL,HMGB1,KCNA4,KCNF1,STMN1,PAK3,PDCD2,PLP1,PPP3CC,PRKCB,PTHLH,RTN1,ATXN2,SEC31A,SLC1A2,SNAP25,SPP1,SYT11,TJP1,TPM1,UBC,MTCH1,WIPF1,CPNE4" Drug CID000091649 hydroxyflutamide Stitch 8.30E-03 1.00E+00 4.03E-02 4.58E-01 26 103 "NCOA1,CNTFR,RNF14,NCOR1,NCOR2,GSDME,ZMYND10,PDLIM5,GDF9,LYVE1,NR3C1,GRM1,GRM5,HSP90AA1,IGF1,MATK,NUCB1,PALM,MAPK8,MAPK9,MAPK10,RET,UEVLD,SAFB,TGFBR3,HEY1" Drug 4791_UP Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "MRTFA,CDC42BPA,APC,RGS20,CADM3,CFLAR,BTRC,CD86,FOXN3,PLEKHB1,RAB28,PLAA,PICK1,CHD1L,FRMPD4,DSCAM,DTNA,EFNA3,DLC1,FGF13,B3GAT1,GRB10,KCNH2,KCNJ5,MBD1,SERPINE2,PPP5C,ASIC4,PPP1R9A,SORCS3,WDTC1,SPTB,SS18,TAC3,TCF7L2,TRIM2,RPGRIP1L,PSD3,BEX4,NDRG4,SLC30A3,SLC17A7,RNF146" Drug 6721_DN Nitrofural [59-87-0]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "AP2A2,MTUS1,ARRB2,CFLAR,SYNJ2,CANX,CHM,TPP1,QKI,WHRN,TBC1D5,EEF1A2,FCF1,SORBS3,IRAK4,BSCL2,LRRC23,ZNF589,FYN,INPP5K,INPP5B,KPNA5,PKM,PLEC,STRN3,POLR2F,SAFB,SBF1,SHMT2,FNDC3A,SLC6A8,ZNF667,SMARCD3,SS18,NXT2,GANAB,ZEB1,ATP13A2,UBTF,NSD2,ZNF711,SH3GLB2,PHTF2" Drug 1562_DN Pimozide [2062-78-4]; Down 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Down 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ADRB2,AK2,PKP4,CASK,ATM,ATP2A2,ZNF337,YTHDC1,ZNF804A,G3BP2,ABI2,LPAR6,PCOLCE2,ERCC2,SYNCRIP,ZNF44,LILRA2,IDH3A,MXI1,SMIM7,MINDY2,DEF8,RDX,DPF2,ZC3H14,FAM192A,SLC2A5,SLC6A8,SLN,SNAP25,KDM3A,EMC1,KANK1,GANAB,GSE1,MLST8,TCF7L2,CBX5,CABIN1,TNS1,HSPBP1,TFIP11,PRDM2" Drug 5607_DN Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ASPHD1,ARID1A,KIDINS220,GAS7,ATP2A2,SYNJ2,CAMK2B,CAMK2G,CRLF1,CHM,TAOK2,SULT4A1,GREB1,DBN1,RASGRP1,SUGP2,EGR3,SORBS3,FAM198B,ZNF589,TRAF3IP2,HBS1L,MUM1,GIT1,RETREG1,EPN1,MINDY2,PRKAR1B,PRPH,ELOVL2,ATG16L1,RET,RGS12,SGK1,EMC1,KAZN,KIAA0930,CABIN1,FAM155A,SLC17A7,SMIM8,PHTF2,SENP7" Drug 3830_UP Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ADCY2,SEMA7A,KCNAB2,APLP1,ASPH,STX16,CACNB2,NEURL1,ZFYVE9,TPP1,STOML1,FADS2,AKAP5,NRG2,PHF14,DAPK3,DTNA,EPB41,ERCC2,CAMSAP1,C1orf61,C1QL1,GPM6A,RASSF8,ITGAM,KCNMA1,LSS,GIT1,PDE3B,PACSIN1,PTAFR,ZFP2,SELL,ASAP3,CPEB3,TNIK,IZUMO4,PEG10,ZBTB43,ATP11A,TBCEL,UBE3A,VAV2" Drug 6884_UP AG-012559 [369370-06-9]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "AK2,ANK1,ATM,STX16,CFLAR,ZMYM4,ENTPD4,SLITRK5,RIMS2,TBC1D5,DBT,DMPK,FCF1,APH1A,TUBD1,FGFR1,GAB1,MSL3,GPR19,GRIK5,ICA1,SCIN,IL6ST,IL12A,ITIH2,MAPT,ADAM22,MINDY2,GON4L,SNRK,PLEKHB2,MCMBP,SAFB,NUBPL,ZNF430,RBM34,ZBTB43,POGZ,SS18,ASTN2,TRIO,ZMYND8,HIRA" Drug 5977_UP pioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "MTUS1,ANK1,APC,SEMA4G,ARHGDIG,NRP2,BTRC,LHX2,AKAP7,IFFO1,CSF1,C2CD2L,ECM2,SGK2,EFNA3,PLXNC1,PTK2B,CAMSAP1,SORBS1,FYB1,DKK3,GAP43,GFER,GNG4,HLF,KCNF1,PALM,CDK18,BCAS3,RGS12,RAVER2,KIRREL1,KCNIP2,NTNG1,AMBRA1,ARHGAP26,KAZN,TK2,CADM1,VAV2,VIPR2,PRDM2,PCBP4" Drug 2634_DN Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ABHD6,ATM,BCL7A,CFLAR,ST3GAL5,SLC25A14,KRIT1,PLEKHB1,DZIP3,DCAF8,DTNA,EIF5,PRKAG2,SMC2,PDLIM5,FAM49B,MPP6,MSL3,GNG4,NR3C1,HNMT,MAP4,MBD1,NEK1,NF1,CEP97,ROBO1,SFPQ,SGK1,SMTN,SIRT2,SLC20A2,SMARCC2,SS18,SUPT5H,TACC1,IQCE,DOCK9,ZMYND8,XRCC4,ZNF24,EMSY,MPPE1" Drug 7045_DN lomustine; Down 200; 100uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ASPHD1,ASIC1,ADD3,AP2A2,LTBP4,CDC42BPA,EPB41L5,APOC1,MARCH3,SLC4A4,SCAPER,CACNA1I,CD86,LHX2,QKI,CSF1,PDE4DIP,ARMCX2,RGS17,ARMCX1,DLC1,TESK2,GLYR1,BRINP3,JAK2,MGAT3,NDUFA5,PDE1C,PDE3B,PMP22,PKIA,SNRK,TMEM104,RGS3,EMID1,FUZ,MAPK8IP3,ATP11A,TACC1,KAT6B,RPRM,GDPD5,PLSCR4" Drug 4640_UP Domperidone maleate; Up 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.37E-03 1.00E+00 4.06E-02 4.62E-01 43 191 "ADCY6,MTUS1,ADGRF5,APBB1,CA4,ARHGEF2,SOCS6,NRXN3,QKI,HOMER3,PDE4DIP,HDAC9,DNAJC6,SGK2,PLEKHO1,DMTN,SPEG,EZH1,AMOTL2,PDLIM5,B3GAT1,FYN,ERAP1,ALDH1L1,GUCY1A2,BACH2,LIG4,LYRM9,NEFM,RETREG1,PLCD1,PTX3,RGS7,NLGN1,ARHGAP26,PHLDB1,SYT1,COBL,VAV2,ZIC3,ZNF24,NAV3,FZD3" Drug CID000045469 sodium nitroprusside Stitch 8.41E-03 1.00E+00 4.08E-02 4.64E-01 56 261 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,ADORA3,AGT,ALDH7A1,CACNA2D1,CALM1,NGB,CBFA2T2,LRBA,CHRM1,CS,SNPH,BLOC1S6,NR1D2,SLC12A6,EDN1,EDN3,EDNRA,EDNRB,ACTL6B,PPARGC1A,GRIN2C,GRIN2D,GUCY1A2,GUCY1A1,GUCY1B1,HBA1,IGF1,KCNMA1,MATN3,NOS1,NPPA,NPR2,NRGN,PDE2A,PDE3A,PDE3B,PDE1B,PRKACB,MAPK3,RYR1,RYR3,SLC6A7,PEG10,PBLD,SST,TAC1,SIRT1,ACTR6,TMPO,VIPR2,MFF" Drug CID000002287 NSC381866 Stitch 8.47E-03 1.00E+00 4.11E-02 4.67E-01 39 170 "ASIC1,APP,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ATP6V0A1,NRP2,GPC2,CALM1,AIFM1,ENTPD2,TPP1,CLTC,SLC32A1,SDC3,DNM2,DNM1L,ATP6V1H,ATP2C1,GHR,GOLGB1,GRIK4,ITGAM,SCG3,P2RY1,PCSK2,ABCB1,PIK3R1,PSMA6,RAB5B,SNAP25,NCDN,STAU1,SYP,TNS2,TF,WNK1,SCG2" Drug CID000001903 8-CPT-cAMP Stitch 8.55E-03 1.00E+00 4.15E-02 4.72E-01 34 144 "ADCY5,ADCY6,ADCY8,ALDH7A1,HCN2,CACNA1E,LRBA,CREM,GCK,GFRA1,GRM7,GRM8,HAS2,IGFBP1,KCNK2,MAP4,HCN1,PDCD2,PDE2A,PDE3A,PRKACB,PRKCB,PRKCG,MAPK3,MAPK4,MAPK7,MAPK8,RGS7,SGK1,SLC14A1,SSTR2,SULF2,ZFP91,CDK20" Drug CID000005234 NaCl Stitch 8.58E-03 1.00E+00 4.16E-02 4.73E-01 110 564 "ABHD6,ADCY2,ADCY5,ADCY6,ADCY8,ADD1,ADD2,SLC12A5,ADORA1,ADORA2A,AGT,APOC2,PDXK,ATM,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,DST,CAST,CARS,CCK,RGN,TAOK2,CLCN4,SULT4A1,HAPLN1,CSNK1E,CSNK1G3,PHACTR3,DCT,DTNB,EDN1,EDN3,TUBD1,PTK2B,TUBB3,TUBB4A,SLC9B2,FGF1,ACTL6B,POLK,ATP8A2,TUBA8,MSTN,GLUL,GPD1,TUBA1C,NR3C1,GUCY1A2,GUCY1A1,GUCY1B1,TNFAIP8L3,HMGB1,TUBB2B,KCNK1,LAMA2,MAP2,MAT2A,MBP,MTR,NBL1,NEFH,NODAL,NOS1,NPPA,NPR2,NUMA1,PFKP,PIK3C2A,PIK3CD,PIK3R1,POLG,MAPK8,SLC26A11,PRODH,LAMA1,PTK2,PTN,REV3L,RNASE1,NEK11,MAPK12,SARS,SCN2A,SCNN1D,HSPA4L,SLC6A7,SLC9A5,SLC12A2,MLC1,TAC1,TAC3,SMG6,LEFTY2,HHIP,ACTR6,PIK3R5,ZNF384,TRH,TUBB2A,TUBB1,CCDC136,WNK1,TUBA1A,NAV2,WNK3,PLD4,ST8SIA2" Drug 1533_UP Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.61E-03 1.00E+00 4.17E-02 4.75E-01 42 186 "ADORA3,AMT,APBA2,PPP4R4,ADGRB2,CFLAR,SYNJ2,ARHGEF2,HOMER3,CLIP3,CSF1,JAKMIP2,MFAP3L,CDON,ERCC2,CAMSAP1,FOXG1,AGAP2,PDLIM5,DISC1,SRCAP,GPER1,GRB10,GSN,HLF,HMGCR,IL6ST,VWA5A,MDFI,SLCO1C1,NTRK3,ELOVL2,RYR1,FNDC3A,FAM214B,TRIM2,SZT2,TK2,TMOD1,ZFP37,NT5M,EVI5" Drug 2694_DN "Trichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 8.61E-03 1.00E+00 4.17E-02 4.75E-01 42 186 "RCBTB2,HOMER3,ARHGEF10,SIRPA,ZNF804A,ZEB2,KBTBD11,ANKMY1,FGR,SYNCRIP,ZMYND11,ERAP1,GRB10,IL6R,LMO2,SMAD1,MEIS2,MTR,PDE4D,KCTD15,FAM216A,PTAFR,RAD51D,ATP8B4,RXRA,TMEM156,DOCK10,SLA,SLC2A5,GSE1,KAZN,TBL1X,TRPM2,ZMYND8,UBTF,LAT2,XRCC4,ZNF32,LRP8,NAV3,ST7,NETO2" Drug 6793_UP Nocodazole [31430-18-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.61E-03 1.00E+00 4.17E-02 4.75E-01 42 186 "ADD2,TRMT9B,KCNAB2,PDXK,MARK4,BMP7,SCAPER,HIP1R,NEURL1,SIPA1L1,GREB1,SMG7,EDN1,CELSR3,FGF13,PDLIM5,TMEM8B,SEPT9,GRK4,GRM1,TJAP1,MITF,ZNF862,PRKAB2,ZSCAN2,C1orf54,ATXN1,SH3BP2,PEX26,PKNOX2,SNCA,PALLD,ZSWIM8,HECW1,SMG6,WSCD1,ARHGEF12,PARD3,TRIO,KCNK12,NAV2,KAT6A" Drug 2353_DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.61E-03 1.00E+00 4.17E-02 4.75E-01 42 186 "ABR,ADD3,AK2,ATM,STX16,CFLAR,BTK,MTMR2,SPAG9,HOMER3,IQCK,CHD1L,DCAF8,MATR3,DTNA,IRAK4,FAM49B,GART,ARFIP1,HSF2,IL6R,JAK2,ZFYVE21,KCTD15,ZNF426,PMS2,SAFB,RAB3GAP1,ELMO2,SMARCA4,SPATA7,ZBTB43,THSD1,NXT2,GANAB,SYT11,EXOC7,TCF4,TCF7,ZNF24,NLRP3,RNF146" Drug 6198_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.61E-03 1.00E+00 4.17E-02 4.75E-01 42 186 "ADD2,ADORA3,MTUS1,ANK2,BMP7,CAMK2G,CBS,HOMER3,AKAP7,ARMC8,COL9A2,CTH,TBC1D5,PCOLCE2,COQ7,RASGRP2,NCALD,FHL1,FOXG1,CAMKK2,GAA,GABRA4,GALC,SRCAP,GRB10,IRF8,MAP4,NINJ2,PRKCZ,PTAFR,RIPOR1,RNH1,PLPPR3,SBF1,ST6GAL1,SLC1A3,DDN,SS18,KAZN,CUX2,PSD3,FLRT2" Drug CID005310993 acipimox Stitch 8.61E-03 1.00E+00 4.17E-02 4.75E-01 19 69 "GPAM,APOC1,APOC2,SCARB1,LRBA,FDFT1,PPARGC1A,HBA1,IGF1,MTTP,GPR85,PLTP,PRKACB,SCN2A,SST,APOM,THRA,SMUG1,NETO1" Drug CID000162602 dopamine quinone Stitch 8.61E-03 1.00E+00 4.17E-02 4.75E-01 19 69 "EPS15L1,DNM1L,GAD1,GAD2,GPR37,PACRG,MAOB,MAPT,NOS1,OPA1,MAPK9,MAPK10,RELN,FBXW7,LRRK2,SIRT2,SNCA,UBC,UCHL1" Drug CID004369535 P-O-O Stitch 8.61E-03 1.00E+00 4.17E-02 4.75E-01 19 69 "KCNH8,CLTA,DCC,DCTN1,PIPOX,PTK2B,GRIN2C,GRIN2D,GRM1,NTRK2,NTRK3,CNTN3,MAPK9,PTK2,CARF,RYR3,TNFRSF1B,TRPC1,TTPA" Drug ctd:C036042 dicyclohexyl phthalate CTD 8.64E-03 1.00E+00 4.19E-02 4.76E-01 157 836 "ADCY6,ADORA1,ADRB2,BCAR3,ALK,BIN1,ANK2,PARG,APC,ALS2,ARHGAP5,CADPS,ATP1A2,SLC4A4,ALDH7A1,B3GALT2,PROM1,SYNJ1,ST3GAL5,BTK,CA12,PTBP2,CH25H,SPAG9,CCK,RGN,CDH2,LGI1,NOG,CFL2,SLC22A6,CLCN3,ABCG2,COL9A3,CP,CPS1,CRYBB1,OSBPL3,PLXNA4,SDC3,HDAC4,TM9SF4,DCT,GRIN3A,SLC12A6,DPP6,DRD1,TOM1,DYRK1A,ABCC5,EEF1A2,RASGRP1,OPTN,APH1A,PLXNC1,IRAK4,PLEKHA1,EN2,OLIG2,ANKRD13B,ERBB2,FABP7,EFEMP1,ST3GAL6,VTI1B,FOXO3,FLT1,PDLIM5,GAB1,TRAF3IP2,ZMYND11,NKX6-2,SULT1C4,GDF9,CYP46A1,ADAM28,GHR,GJB1,HPGDS,INSM2,GRIA1,PLCD4,NR3C1,GRM7,GSN,TOX2,HRH3,HMGCR,HSD17B1,IGF1,ITGA7,KCND1,KCNJ3,LSS,MAOB,MAT2A,MMP17,MSI1,NEFH,NEUROD1,NFYA,NPR2,NPTX2,SLC11A2,NUCB2,PAH,PC,PCSK1,PDE4D,PKM,EXOSC10,MED1,MAPK4,MASP1,PTPRB,RET,PBRM1,RPE65,FBXW7,LRRK2,CLIP1,MAPK12,SOX6,TRA2B,SLC1A3,SLC6A1,SLC8A3,SLC12A2,SLC12A4,SLC15A2,SMARCE1,SNAP25,KDM4C,SPTB,SAMSN1,ARC,SYP,SYT1,TCF12,SLC19A3,ARHGEF12,DICER1,SIRT1,THRA,TIAM1,PARD3,NR2C2,TRPC3,TSC1,TST,VAV2,BEST1,ZIC3,PMEPA1,SLC38A1,TUBA1A,IFT88" Drug ctd:C089032 rimonabant CTD 8.78E-03 1.00E+00 4.25E-02 4.84E-01 57 267 "ACADM,OSBPL8,APP,RGS11,CALM1,CANX,SCARB1,LRRFIP1,LARGE1,CCPG1,CLTC,CNR1,ACBD5,ATRNL1,SIPA1L1,TOMM20,FBXL5,TSPAN5,HIPK3,MBNL2,EIF4G2,EIF5,PLEKHA1,ST3GAL6,FGF1,PCYOX1,GFAP,GLS,FERMT2,GRIA1,NR3C1,ZHX1,HSP90AA1,IGF1,RBPJ,ITGAV,LAMP2,LMO1,MBNL1,MEST,NAP1L1,OPA1,PC,PPP3CA,MAPK3,MAPK8,FBXW7,CHD9,FAM126B,MYCBP2,TCEA1,WDR7,ARHGEF12,TPM4,VLDLR,CSDE1,CAB39L" Drug CID000002337 benzocaine Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "ASIC1,ASIC3,ACOT8,SCN2A,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TAC1,NPL" Drug CID000123839 mag-fura-2 Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,ENTPD2,ATP2C1,RAPGEF4,QDPR,RIT2,RYR1,RYR3,CNTN2" Drug CID005281656 norathyriol Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "PLCXD3,GPR162,PLCD4,MBP,PLCB2,PLCD1,PPARA,PRKCB,PRKCG,PKN2,PRKCZ,PLCB1" Drug CID000123934 DTAF Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "KDM5D,ALK,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,SLC12A2,TUBB2A,TUBB1,TUBA1A" Drug CID000104929 "L-365,260" Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "APOC2,CCK,CCKBR,BOC,AASS,PTK2B,PENK,PTK2,SST,TAC1,TACR1,RGMA" Drug CID004631218 AC1NDT8A Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "ASIC1,SLC24A4,SLC24A2,COL4A5,SRGAP3,ACSL4,RALGDS,FNDC3A,SLC8A2,SLC8A3,SHANK2,TNS1" Drug CID003749170 Compound 10 Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "ACOT8,GPHN,GRM2,PTPN5,HMGCR,MID1,PTCH1,TMEM132D,CLSTN2,SYNE1,TMEM121,SMUG1" Drug CID000004296 TFMPP Stitch 8.85E-03 1.00E+00 4.27E-02 4.86E-01 12 37 "ABR,DMTN,TUBB4A,ZMYND10,CIT,HTR2A,HTR5A,SOX10,JMJD6,PLCB1,ZEB1,TMEM121" Drug CID000002915 cystamine Stitch 8.86E-03 1.00E+00 4.27E-02 4.86E-01 41 181 "APAF1,NCOA1,ATP2B1,CDO1,NPIPA1,CNR1,HDAC9,DYNC1I1,ATN1,DTNB,EN2,ENO2,PPP1R1B,FOXG1,PDLIM5,GFAP,PPARGC1A,TCERG1,PACSIN2,HP,HPR,OGG1,PAH,PENK,ABCB1,SERPINE2,PLIN1,PACSIN1,MAPK8,MAPK9,MAPK10,QDPR,FBXW7,ATXN1,ATXN7,FOXRED1,SLC1A3,SNCA,ZNF423,PRTFDC1,JPH3" Drug 6070_UP Benzethonium chloride [121-54-0]; Up 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.86E-03 1.00E+00 4.27E-02 4.86E-01 41 181 "LTBP4,CFLAR,BTRC,SLC16A4,CLGN,CHM,CNR1,VCAN,RASSF2,DLG4,TENM1,ELAVL4,ELN,HSD17B14,LRRC23,GAD1,ATP8A2,RND1,GPD1,STON1,GPER1,KCND3,SLCO1C1,CNOT4,PCBP3,CDK18,PLTP,MINDY2,SAMD9,C1orf54,ENOX1,RPS6KA2,ZFP2,SH3BP2,SLC9A5,UNC5B,RGL1,KIAA1107,TRIM2,VLDLR,NUP214" Drug CID000074537 "1, 3-diallylurea" Stitch 8.90E-03 1.00E+00 4.27E-02 4.86E-01 20 74 "ASIC1,ATP2A2,CACNA1E,RUNX1T1,ASIC3,CHRM1,GDA,TOX,DNER,GATM,MX1,ABCB1,SCN3A,SCN4B,SCN7A,SCNN1D,ASIC4,SCN3B,TK2,HPS4" Drug CID000010340 sodium bicarbonate Stitch 8.90E-03 1.00E+00 4.27E-02 4.86E-01 20 74 "ADCY5,ADCY6,ADCY8,SLC4A4,CA4,CA12,SLC4A7,SLC4A8,CALY,ADGRV1,TUBA8,IDH3A,ITPKB,PIK3C2A,RET,MRAS,ZNF365,SLC1A3,TF,NR2C2" Drug 5079_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALDH4A1,ALDH7A1,CDK5R1,FOXN3,HOMER3,AKAP7,HAPLN1,CSF1R,PPP6R2,DCAF4,GIT2,DNAJC6,DLG3,EDIL3,STX2,TUBB4A,FYN,ARHGAP19,SCIN,INPP5B,MAPT,MX1,ZNF426,MAPK7,KLK6,BCAS3,SYTL2,SBF1,SCN8A,DZIP1,WDTC1,ZBTB43,TCF4,ARHGEF12,CRTC1,AHCYL2,ATP13A2,GPR161,PARD3,TNS1,CADM1,ZNF711,SH3GLB2,MAP3K12" Drug 1676_UP Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALCAM,AMH,APC,CDC14B,PPP4R4,PLA2G4C,ATM,B4GALT6,LHX2,ZFYVE9,HOMER3,SH2B1,CTIF,KBTBD11,ATN1,DENND4A,EFCAB2,COPS8,GRB10,ELOVL5,IL6ST,NEK1,NF1,SETD4,PALM,CDK18,PLCD1,PACSIN1,TNPO2,POLG,MED1,WDR25,RAD52,RGS3,GSTCD,FBXO11,ST6GAL1,SLN,KIF13A,WDTC1,SYN2,TCF7L2,PCDHGA10,PHTF2" Drug 5916_UP thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADRA1D,AMH,SEMA7A,KCNAB2,EPB41L5,APOC1,MARK4,ALDH4A1,ATP6V0A1,CLU,NECTIN3,CSF1R,DCAF4,RUSC2,TMCC2,EDNRA,EFNA3,ERCC2,TESK2,OLFM1,FHL1,GAD2,GRM1,NXPH3,TJAP1,MOBP,NF1,NUMA1,SMOX,MAPK7,PREX2,ZKSCAN3,KIF13A,WDTC1,ZSWIM8,RGL1,TRIM2,ARHGEF12,GPR161,CDK20,CHST5,MICAL1,LAT2,SSPN" Drug 3683_DN Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALAD,AMT,PKP4,APC,APOC1,CDK13,SLC4A4,MTMR9,CFLAR,HAP1,CCNT1,ARHGEF2,PICK1,IQCK,DAPK3,IRAK4,ZNF589,TPK1,ZMYND11,INPP5K,GLRB,LIG4,MBD1,SAMD9,FAM120C,RAB3IL1,RAD51D,NEK11,ZFP30,DZIP1,PREX2,PPP4R3A,ARHGEF40,CCDC88A,SLC20A2,KDM4C,SPTAN1,NXT2,ASTN2,PSD3,CHST8,RPRM,NSD2,TFIP11" Drug 6138_DN Ciprofibrate [52214-84-3]; Down 200; 13.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PPFIA1,PKP4,APC,MARK4,ZSCAN18,ATP6V0A1,BCL7A,CHM,CRMP1,SLITRK5,DBT,CAMSAP1,FHL1,GAA,GABRA4,SEPT9,ZNF276,GLYR1,GNG4,GPD2,PADI2,AGBL5,LIG4,MID1,MPP2,ZNF862,NINJ2,PENK,CCSER2,PTPN13,MARCH1,RAB3IL1,CEP97,RAP1GAP,ZCWPW1,MAP6D1,FOXRED2,WDTC1,RAP1GAP2,JMJD6,ARHGEF9,TNS2,CHST8,ZIC3" Drug 4553_DN U-62066 [87151-85-7]; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MAP7,TPP1,DNAJB5,QKI,NIPBL,CREM,HINFP,PLPPR4,EXOG,EFNA3,EN2,CGREF1,B4GALNT1,C1QL1,GLYR1,GPR17,EML4,GRIK2,SCIN,INPP5B,MIA2,NLE1,GON4L,FAM120C,RIPOR1,RGS3,MYH14,KIF16B,SHANK2,WDTC1,TNIK,SYT11,SYT1,ASTN2,WWC1,IQCE,CABIN1,SSBP2,OSBP2,NSD2,NDRG4,HPS4,WIPF2,MPPE1" Drug 2130_DN Rescinnamin [24815-24-5]; Down 200; 6.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASIC1,NDRG2,ADORA3,ADRB2,AMPD2,CACNB2,CAMK2G,FOXN3,HOMER3,EXOG,TRAPPC9,EFNA3,CD320,ZNF589,SEMA4D,AFF2,KHDRBS3,GAB1,GABRA4,GNG4,CACFD1,KCNJ5,MATK,MYT1,OXTR,CDK14,NLE1,STRN3,POU6F1,RAB3IL1,ZNF821,SLC11A1,BTBD7,WDTC1,DOK5,IZUMO4,DDN,MLC1,KAZN,DNMBP,THBS4,THRA,TMOD1,TPM2" Drug 4777_DN Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AK2,ANK3,PPFIA3,APP,ALDH4A1,STX16,KIF1A,GYG2,OSGIN2,SLC25A14,KRIT1,HOMER3,AKAP7,CREM,ABCG1,CSNK1E,PDE4DIP,CTNND2,MFAP3L,FBXL5,SUGP2,SORBS3,FKTN,FGFR1,PDLIM5,MPP6,KCNJ3,MAP4,ZNF862,PRKAB2,MSANTD2,FOXRED2,SBF1,SGK1,SH3BP2,TMCC1,SPTAN1,TTBK2,ATP11A,EXOC7,TBL1X,DOCK9,VPS35L,KAT6A" Drug 2342_DN Mephenesin [59-47-2]; Down 200; 22uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABR,ASIC1,MAP4K3,PPFIA1,CDK10,ARNTL,NUMB,SLC4A4,STX16,MTMR9,SYNJ2,CAST,FADS2,IQCK,ARMC8,CSF1R,FEZ1,ARHGAP32,C2CD2L,DPH1,TSPAN5,PHF20L1,OGA,ERAP1,RAB40B,DIDO1,MAP4K5,IFI16,NF1,NFYA,PDE3B,PPP3CC,GON4L,RGS10,SH3BP2,EMC1,DDN,ZNF302,ANKRD12,ARHGEF12,TLR4,CADM1,PLPPR2,VIPR2" Drug 5828_UP Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APC,ALDH4A1,SLC4A4,BACH1,NRP2,PCYT1B,IPCEF1,VCAN,ZNF337,DAPK3,GIT2,ETV1,CORO2B,FGF1,TRMO,ZMYND11,JAK2,LIG4,NLE1,SLC25A23,SEPT4,PRKAR1B,FAM184A,SUGCT,GSTCD,NEK11,CSRNP3,MRAS,RASA3,FNDC3A,ELMO2,LIMCH1,SNCA,SS18,KIAA1107,HIRA,UBTF,VGF,WIPF1,TFIP11,EVI5,NAV3,SLC17A7,EPM2A" Drug 5463_DN Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTUS1,AK2,C1QTNF3,ANK3,PKP4,APBB2,APC,PPFIA3,BCL2L2,ST3GAL5,MTMR2,C5,KYAT1,LHX2,ZFYVE9,COL9A2,PDE4DIP,DTNA,COQ7,NOP56,TRMO,USP21,HPS5,ACOT7,ITPKB,MITF,SLC25A23,PRKAB2,PSMD13,ROBO1,SBF1,KIF16B,TTC17,TMCC1,RBM34,TROVE2,ELOVL4,PHLDB1,TCF7L2,VGF,XRCC4,ZNF74,MAP3K12,RNF146" Drug 5066_DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NME5,ALDH7A1,SCAPER,CANX,MAP7,FOXN3,CHM,QKI,BAG4,NRG2,VCAN,EDRF1,DBT,DNAJC6,PARD6A,EDIL3,F3,BAIAP2,ANKFY1,DENND2A,TMEM8B,GLRB,GPD2,IL6ST,SLC11A2,PIK3R1,LRP12,CNNM2,SAMD9,ZSCAN32,IFT122,WDTC1,TNIK,EMC1,KDM4C,BEX1,IQCE,ARHGEF12,BHLHB9,UGT8,SPHK2,PLSCR4,FZD3,PHTF2" Drug 1825_UP Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG3,ARNTL,ASPH,CFLAR,CDK5R1,IL33,ZFYVE9,CLCN3,HOMER3,CRY2,PDE4DIP,DBT,PARD6A,RABGAP1L,EPB41L2,ZNF589,FGF1,B4GALNT1,GNAS,GPR17,EML4,HNMT,ARHGAP12,MATN3,MBNL1,NFYA,CNOT4,PDE4D,ZFYVE21,CNNM2,PTPRN2,RAP1GDS1,TRAPPC13,TMEM156,OGDHL,KDM4B,EPB41L3,NXT2,ARHGEF9,TRIM2,TST,UBE3A,XRCC4,MAP3K12" Drug 6320_DN Nimodipine [66085-59-4]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTUS1,CDC14B,NUMB,ALDH7A1,ADAM15,CHD1L,PDE4DIP,SMG7,FEM1B,SIDT2,LRRC23,FCGRT,DLL3,OGA,B4GALNT1,MSL3,GPD2,GUCY1A1,RASSF8,IPO5,NFYA,CNOT4,PC,NLE1,MAPK3,MAPK7,PRPH,PSMD13,SEC61A2,RXRA,MAPK12,ASAP3,FUZ,NLGN1,KBTBD4,SPATA7,POGZ,SEPT8,ARHGEF9,ASTN2,LMF1,XRCC4,PCBP4,MPPE1" Drug 3514_DN Lymecycline [992-21-2]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABHD6,PLA2G6,EPB41L5,PLA2G4C,MARK4,CFLAR,SYNJ2,SOCS6,HOMER3,AKAP7,SH2B1,ARHGEF4,DBN1,MFAP3L,RUSC2,SMG7,RCAN1,OPTN,EGFR,STX2,EZH1,FHL1,MSL3,STON1,JAK2,MBD1,NEK1,NF1,CNOT4,SERPINE2,TMEM104,RGS12,ANKRD6,SLC20A2,WDTC1,VPS13A,POPDC3,KIAA0930,TRIM2,SLC44A1,CABIN1,ZMYND8,WNK1,RNF170" Drug 1410_DN Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALCAM,APP,SHTN1,ATP2B1,KRIT1,CD38,RCBTB2,SLC4A7,FEZ2,CSNK1G3,CTH,HDAC4,MATR3,ZEB2,KIAA0753,DMTF1,RCAN1,FEM1B,EPB41L2,DENND4A,SEC23B,ATP2C1,GART,ARFIP1,GLS,HTATSF1,MAP4K5,HNMT,AGFG1,LAMP2,SLC11A2,PDE3B,PPM1B,PPP5C,MRPS18A,C12orf49,CCDC88A,EMC1,EPB41L3,LARP4,NXT2,TACC1,KCTD2,UBE3A" Drug 1408_UP Pentylenetetrazole [54-95-5]; Up 200; 29uM; HL60; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG2,ALAD,APBB2,ARRB2,PDE8B,RGS11,BMP7,SYNJ2,CACNA1I,LDLRAD4,RUNX1T1,CD86,RAB26,CRYM,ARHGEF10,ING4,KAT8,PRKAG2,FHL1,FLNC,EFCAB2,ATP2C1,HBS1L,ALDH1L1,SRCAP,PCDH17,GPR12,GRIA4,KIF5C,NELL2,NF1,PDE3B,CAMKV,POLG,CRTAC1,RGS10,ARHGEF10L,TCP11L1,FBXO11,SLC2A5,SYT1,ARHGEF12,CDH22,TK2" Drug 3096_DN S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASPH,SLC16A4,SCARB1,SOCS6,RCHY1,CSF1,ZNF337,RIMS3,DBN1,HIPK3,PTK2B,KIAA1109,CAMSAP1,CAMKK2,GALC,GPD2,GPR22,PCLO,ICA1,LAMA2,NINJ2,NUMA1,OGG1,PTPA,CNTLN,PTN,PTPRO,TMEM156,DGLUCY,ANKRD6,SLC1A7,PPP4R3A,ZNF667,DOP1A,TNIK,ZCCHC24,EMC1,RBM26,FAM168A,JMJD6,ATP11A,MKRN3,REEP1,EMSY" Drug 3099_DN Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG3,KIDINS220,OSBPL1A,ALAD,APBB2,APC,CAMK2G,SCARB1,CLGN,NIPBL,AKAP7,CSF3R,RUBCN,HDAC9,TM9SF4,RIMS3,DTNA,EIF4G2,BSCL2,ENO2,FHL1,PDLIM5,ATP2C1,CSPG5,ALDH1L1,GPD2,NFYA,LRP12,MAPK3,MAPK7,SEC14L1,FAM214B,KDM4B,TNIK,TROVE2,JMJD6,CAMSAP2,AHCYL2,SLC44A1,KCTD2,TPM3,WBP2,ZKSCAN5,UBE3B" Drug 2557_DN Flecainide acetate [54143-56-5]; Down 200; 8.4uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABHD6,MTUS1,MRTFA,DOC2A,BIN1,APC,CDC14B,DNAH17,SLC4A4,MTMR2,CAST,TAOK2,SIPA1L1,ZFYVE16,SIDT2,ABI2,SORBS3,DLC1,FGFR1,PDLIM5,CSPG5,GAD2,SEPT9,SRCAP,GNG3,SPACA9,MAP4K5,AGFG1,ITGAM,MAP4,SCAMP5,NF1,NINJ2,CDK14,SYTL2,CNKSR2,SLC12A2,RBM26,FBXW11,TPD52,TPM3,EMSY,PCBP4,FAM13C" Drug 5872_DN Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADD2,BIN1,APBB2,APOC1,PPFIA3,APP,ASPH,ALDH7A1,HIP1R,CNTNAP2,CTH,GIT2,DLG3,EFNA3,EFNB3,ING4,STX2,TESK2,DLL3,ERAP1,INPP5K,GLS,GPM6B,RASSF8,INPP5B,JAK2,MBD1,ZNF862,NF1,NFYA,NPR2,ELOVL2,RAB3A,RAB3IL1,CEP97,RGS10,SH3BGR,SH3BP2,FNDC3A,EPN2,MAPK8IP3,TRIM9,SYNC,NAV3" Drug 5867_DN Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABHD6,AMT,SLC4A4,CFLAR,NFS1,ZFYVE9,CSF1,ZNF337,KIAA0586,DBT,SMG7,SGSM2,PLXNC1,IRAK4,ING4,INPP5K,GART,GLRB,GNG4,GPM6B,NR3C1,MAP4K5,HSF2,IL11RA,MAPT,MBD1,SCAMP5,NUMA1,PDE4A,MAPK3,RAB3A,AMBRA1,PPP4R3A,SLC22A4,TMCC1,KDM4B,PEG10,GSE1,IQCE,TRPM2,XRCC4,EMSY,PRDM2,ACTR3B" Drug 3268_DN Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,ALCAM,EPB41L5,GAS7,PPFIA3,ATM,CFLAR,CA4,MAGI1,CACNA2D2,SRSF11,NMT2,CRY2,CSF1,DLG3,RCAN1,EFNB3,STX2,FECH,GPR153,OGA,ZNF44,HBS1L,TXNL4A,GPR19,GSN,IL6ST,ITPKB,KIF2A,RETREG1,ZDHHC14,RGS12,EMID1,FUZ,PPP4R3A,ZCCHC24,EMC1,POGZ,AP4E1,BEX4,VAV1,UPF3A,NAV2,EPM2A" Drug 1944_DN Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "BRAP,PLA2G6,CAPRIN2,STX16,SYNJ2,FUBP1,AIFM1,TBRG4,NIPBL,HOMER3,PREPL,FEZ2,PUM1,LYPD1,RCAN1,BSCL2,DCTN4,ETV1,OGA,GLS,PRRC2B,CACFD1,ACOT7,KLC1,MAP4,GIT1,NEK1,CDK14,PLEC,PPP5C,PSMD13,RIPOR1,FAM192A,SLC11A1,SMARCA4,NMNAT2,EXOC7,DMXL2,RBFOX2,TSN,HSPBP1,ZFAND5,FXR1,LAS1L" Drug 2912_DN Beta-sistosterol [83-46-5]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AP2A2,MRTFA,PPFIA4,PPFIA1,APBB2,APP,ASPH,C5,SOCS6,MICAL2,PDE4DIP,ZEB2,B3GAT3,RABGAP1L,ABCC5,FCF1,RRAGB,FHL1,CGREF1,ZNF44,GLYR1,PADI2,ITPKB,KPNA5,NUMA1,OGG1,CCSER2,PLEC,STRN3,MINDY2,PTPA,CARF,FBXO11,ZC4H2,STX1A,KLHL7,TCF4,TCF7L2,KAT6B,TNS1,TPM1,TPM2,PRDM10,NLRP3" Drug 7253_DN Methylatropine nitrate [52-88-0]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AP2A2,BIN1,MADD,ARHGAP5,ARNTL,ASPH,OSGIN2,CPS1,B3GAT3,RHOBTB1,TRAPPC9,RCAN1,ELAVL2,EPB41L1,F8,TUBB4A,ANKFY1,ARFIP1,RASSF8,KLF12,HNMT,HSF2,KHK,ARHGAP12,MIA2,MITF,ZNF862,PC,SNX10,LRRC49,ELOVL2,RAP1GAP,ZC3H14,PDZD2,ATP11A,ANKRD12,PDLIM2,TK2,CABIN1,METTL3,TSC2,PLPPR2,LMF1,MPPE1" Drug 4684_DN Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AMT,PPFIA4,APBB2,ATP1A3,FUBP1,CREM,HAPLN1,VCAN,CNTNAP2,BRINP1,MFAP3L,ATN1,ING4,F5,C1orf61,GABRA2,ERAP1,IGFBP1,NDP,NF1,NFIX,CLDN11,PLXNB1,PRPH,CNTLN,PTCH1,PTPRN2,FAM120C,TMEM231,RGS7,MYH14,ZNF671,MCMBP,NLGN1,SLN,MYH15,SOX15,IZUMO4,RBM26,THRA,TMOD1,VGF,WIPF1,STMN4" Drug 3298_DN Cholecalciferol [67-97-0]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADORA2A,AP2A2,MTUS1,APBB2,CAPRIN2,BMP7,GYG2,CACNA2D2,PLEKHB1,PLAA,CREM,FAM169A,DTNA,SIDT2,ING4,F3,F8,HBS1L,MSL3,HNMT,KIF5C,IPO5,LIG4,KITLG,NEK1,NF1,CNOT4,SLC11A2,SETD4,CDK18,RETREG1,WDR25,ROM1,LIMCH1,TSPYL2,TROVE2,MAPK8IP3,ELOVL4,ATP11A,FBXW11,TRIM2,TIAM1,UBE2H,PRDM2" Drug 1576_UP Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ACTN1,NDRG2,SPOP,ALDH4A1,MTMR2,PHC2,ANKRD46,FAM13A,RASGRP2,ECSIT,KIAA1109,PRKAG2,CAMKK2,OGA,FYB1,NXPH3,ITGAM,ITGAV,KCNH2,MAP4,MBD1,NEFH,NPPA,PLCD1,MBOAT7,TMEM260,RAD51D,TRIM68,ZNF671,URGCP,SON,ZSWIM8,ERC1,CDK19,THSD1,VAMP1,ANKRD12,MCF2L,TCF7L2,DICER1,CBX5,TRPM2,FLRT2,LMAN2L" Drug 826_DN prazosin hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADD3,ANK3,CDK10,ARHGEF7,C5,QKI,HOMER3,PARD6A,ACOT8,DTNA,RBM12,EFNB3,STX2,VPS26C,RACK1,FHL1,TRMO,GPER1,DHX35,MAP4,NF1,NFYA,PRKACB,C1orf109,RIPOR1,RAD51D,SFPQ,SUPT20H,NUBPL,PPP4R3A,SLC15A2,KDM4B,EMC1,ITPRID2,SS18,NSFL1C,MTCL1,IQCE,TCF7,TCF7L2,KAT6B,NSD2,SEMA3B,MPPE1" Drug 4535_DN Parbendazole [14255-87-9]; Down 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTUS1,BIN1,ARRB2,KIF1A,BAIAP3,AKAP5,CREB5,ABCG1,PDE4DIP,CNTNAP2,EXOG,DMPK,EDNRA,CNNM1,MBNL2,LPAR6,TNK2,SPEG,ETV1,TUBB4A,BAIAP2,ERAP1,TDRKH,INPP5B,ITPKA,LSS,MX1,NDP,NDUFA5,SAMD9,FBXW7,FAM192A,SAFB,DZIP1,SLC1A7,MAPK8IP3,CRTC1,TIAM1,LMF1,ZBTB14,NT5M,HPS4,KCNAB1,SMIM8" Drug 2186_DN Evoxine [522-11-2]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG2,APP,OSGIN2,CAMK2G,CAPN3,SH2B1,FEZ1,CSNK1E,PDE4DIP,CTNND1,SV2A,DTNA,SIDT2,EFNA3,LPAR6,ING4,TNK2,RASGRP2,KAT8,GABRA4,TRAF3IP2,SEPT9,SRCAP,CRCP,ATXN2L,MAP4,MEF2C,NEK1,CCSER2,ST8SIA5,PILRA,MINDY2,PPP5C,PTAFR,RALGDS,TRAPPC13,BTBD7,DBNDD2,SS18,KIAA1107,TNS1,ZKSCAN5,FLRT2,UBE3B" Drug 7465_DN Spaglumic acid [4910-46-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AK2,APC,MARCH3,CAPRIN2,ASPH,EIF4G3,ATP6V0A1,AP4M1,ADGRG1,HOMER3,COL4A5,HINFP,ARHGEF10,EDRF1,KIAA0586,GIT2,C2CD2L,DLG3,SORBS3,VPS26C,SCML2,AHDC1,NF1,PDE3B,STRN3,NKAIN1,RAB3IL1,RAD51D,RGS12,KDM4B,CLASP2,NXT2,FCHO1,PHLDB1,ARHGEF9,TCF7L2,AHCYL2,HEY2,NPL,VIPR2,EMSY,MPPE1,ST7,SMIM8" Drug 3350_DN Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "C1QTNF3,AMPD3,APC,PPFIA3,ASPH,CLGN,FOXN3,FADS2,DCAF4,DOCK4,DCAF8,DAPK3,FBXL5,HSD17B14,STX2,RRAGB,PDLIM5,PRELID3A,HBS1L,ERAP1,SRCAP,ELOVL5,KCNJ5,MPP2,NUMA1,PDPK1,PLCD1,PPP5C,MAPK8,PRPH,PEX5,ZCWPW1,RGS12,RPS6KA2,SEC14L1,PEX26,GLT8D1,EMC1,POPDC3,EXOC7,KIAA1107,TK2,KLC2,SSPN" Drug 3171_DN Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "C1QTNF3,MRTFA,APBB2,APC,PPFIA3,ASPH,CDK5R1,SCAPER,CFAP410,CACNA1D,GPRASP1,FCF1,CNNM1,SIDT2,OPTN,EIF5,ING4,COQ7,FECH,FGFR1,ANKFY1,PRELID3A,CGREF1,TDRKH,GRB10,IL6ST,NFYA,PRKAB2,PRKAR1B,ZNF821,FUZ,SLC1A7,SLC20A2,KIF13A,THSD1,VAMP1,TACC1,NSD1,ZNF34,TMOD1,TPM1,PLPPR2,VIPR2,EVI5" Drug 1796_UP Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALAD,EP400,KCNAB2,ALDH4A1,FOXN3,ZFYVE9,PDE4DIP,DBT,PLPPR4,EDNRA,FEM1B,PLEKHO1,SPEG,RRAGB,F8,RACK1,SMC2,SESN1,GNAS,ICA1,MYO6,NOS1,PIK3R1,PLCD1,CDIP1,SYTL2,RAB3A,ACSS3,FAM184A,ST6GAL1,KDM4C,UNC5B,TAB2,COLGALT2,TTBK2,ASTN2,CHST8,METTL3,VIPR2,WIPF1,XRCC4,TRIM9,SPHK2,DPF3" Drug 6045_DN Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "C1QTNF3,SRPX,AMPD2,PPFIA3,ARHGDIG,CDK5R1,CA12,CAMK2G,ARHGEF1,PLEKHB1,AKAP7,RCHY1,HDAC4,RASSF2,DAPK3,EXOG,DTNA,EFNA3,IRAK4,ZNF589,C1orf61,GART,DHX35,IL6ST,KCNH2,MMP16,ADAM22,ZNF862,PMP22,STRN3,LRP12,PRKAR1B,RIPOR1,ZDHHC14,RGS10,WLS,SMTN,BTBD7,KIAA0930,PSD3,CRTC1,TK2,TRPC1,PRDM2" Drug 3877_DN alpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AP2A2,DOC2A,KCNAB2,APLP1,MARK4,CFLAR,GYG2,CRLF1,TAOK2,FADS2,SH2B1,PDE4DIP,ARHGEF4,DRD1,SIDT2,EFNB3,ING4,GAD1,SRCAP,GLS,POLL,GNAS,PCLO,CACFD1,KHK,MAPT,BCO1,NF1,NLE1,PLXNB1,POLG,MAPK10,RAB3IL1,DCUN1D2,SH3BP2,ASAP3,SMTN,SMARCC2,ZCCHC24,NCDN,ATP11A,TNS2,CRTC1,VAV2" Drug 7311_UP Tiletamine hydrochloride; Up 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTUS1,ALK,CDK10,ALDH4A1,ALDH7A1,SCAPER,CFAP410,MAP7,RUNX1T1,SOCS6,KIAA1549L,PPP6R2,EDNRA,HIPK3,CELSR3,AASS,RRAGB,FGF1,SYT17,GLYR1,GNAL,GNG3,MIA2,AFF1,NRCAM,PALM,PIK3R1,CCSER2,POLG,ARID4A,TTLL7,ZNF821,ZFP30,SH3BP2,AMBRA1,ANKRD6,SNCA,KIF13A,SPTAN1,JMJD6,RPGRIP1L,SYNE1,CRTC1,DNAH7" Drug 2751_UP Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "SYN3,LTBP4,ANK1,PPFIA3,NOL4,CFLAR,SYNJ2,TAOK2,FADS2,CNTN1,SH2B1,CRMP1,CRY2,NCOR2,SNCAIP,CDON,SLC12A6,FGF1,HPGDS,GNAS,GPM6A,GRM1,ATXN2L,INPP1,KHK,MAP4,MDFI,SLC25A23,ELOVL2,PTN,ZDHHC14,SYNDIG1,KCNIP1,STUM,ST6GAL1,SP4,INKA2,ACSBG1,VAMP1,TNS2,CRTC1,TGFBR3,ZNF45,SYNC" Drug 415_UP nordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG2,MTUS1,APBA2,APOC1,ALDH4A1,SYNJ2,MTMR3,CAMK2A,SLC22A6,NIPBL,GIT2,EXOG,DYNC1I1,SIDT2,SUGP2,EGR3,CALCRL,VPS26C,KIAA1109,PDLIM5,GART,ALDH1L1,HTATSF1,GPD2,GPR19,EML4,BTN2A1,IGF1,IL6ST,MITF,AFF1,NF1,CCSER2,PMS2,PPP2R2B,RET,TMEM206,FNDC3A,KDM4B,NXT2,SEPT8,TBL1X,TEX15,HPS4" Drug 2089_DN Piroxicam [36322-90-4]; Down 200; 12uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "BIN1,CNTNAP1,RCBTB2,CLCN4,CLU,HOMER3,WHRN,CSNK1E,DAPK3,RUSC2,KLHL3,ING4,EPB41L1,SEPT9,INPP5K,ARHGAP19,INPP5B,MIA2,MPP2,ZNF862,SETD4,PC,FA2H,SAMD9,APTX,GON4L,FAM184A,NUDT11,SAFB,SBF1,ST6GAL1,KDM4D,SLC20A2,WDTC1,CAND2,SS18,ROBO3,KIAA0930,AHCYL2,ATP13A2,HIRA,LMF1,ZNF32,AAAS" Drug 5815_DN Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADRA1D,AK2,OGT,ASPH,ATM,CFLAR,CSF1,CSNK1E,DCAF8,SMG7,SGSM2,SUGP2,EFCAB2,CINP,PDLIM5,RNFT2,MAP4K5,MAN1B1,DHX35,IL6ST,DIPK1A,KIF5C,MAN2A2,MT1M,NF1,NFYA,PLCD1,ZNF426,ELOVL2,RIPOR1,SH3TC2,KIRREL1,AMBRA1,WDR37,ZNF430,SMARCC2,CDK19,ELOVL4,COBL,EXOC7,SATB2,TNS2,TMPO,METTL3" Drug 7180_UP Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASIC1,APC,APLP1,SCAPER,BAIAP3,BTRC,CAMK2B,QKI,RCHY1,DAPK3,HP1BP3,LYPD1,DLG3,EGFR,PLXNC1,COQ7,MTSS1L,F8,SEMA4D,ANKFY1,DPYSL4,PDLIM5,GART,GFER,TXNL4A,EML4,GRB10,LIG4,NF1,PDE1C,ZCWPW1,RGS12,TCP11L1,TRAPPC13,SH3BP2,BTBD7,CLASP2,NXT2,PHLDB1,TRIM2,AP4E1,XRCC4,GDPD5,ST7" Drug 6578_UP PHA-00665752 [477575-56-7]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ALCAM,AMH,AMPD3,APLP1,PPFIA3,CDK10,MARK4,ALDH7A1,CFAP410,CA4,CA12,KYAT1,SOCS6,HSD17B14,CDKL3,FGFR1,FAM49B,PRELID3A,SIGLEC8,DISC1,MSL3,GRB10,NR3C1,SLC2A6,INPP1,NPR2,PCDH9,RAD51D,RGS10,PAQR6,PPP4R3A,OGDHL,WDTC1,SPTAN1,ST5,MAPK8IP3,ELOVL4,TTBK2,TNS2,SIK3,SLC44A1,ZKSCAN5,UPF3A,MAP3K12" Drug 6175_DN LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASIC1,ABHD6,APAF1,ATM,C5,EPS15L1,RCHY1,C2CD2,SH2B1,APPL1,B3GAT3,KIAA0753,SGSM2,NR1D2,DTNA,FAM13A,ING4,COQ7,ANKMY1,SRCAP,COPS8,GLYR1,GLS,PRRC2B,GPR22,ATXN2L,TJAP1,RGS3,LGR4,PLPPR3,TMEM156,FBXO11,DZIP1,SIRT2,SLC20A2,WDTC1,MAPK8IP3,TACC1,CAMSAP2,ZKSCAN5,HIRA,LAT2,ZNF32,FIP1L1" Drug 5438_DN Protriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADRA1D,SEMA6A,APBB2,ARHGDIG,CLGN,TAOK2,QKI,COL4A5,SDC3,EDRF1,RIMS3,MRNIP,VPS13B,KAT8,POLR1B,GART,SRCAP,GLYR1,GPER1,BRINP3,INPP5B,JAK2,KPNA5,NTRK2,PCDH9,PDE3B,LRP12,PTHLH,ZSCAN32,ZCWPW1,GSTCD,SLC1A7,EMC1,INKA2,PHLDB1,PLCB1,ATP11A,EXOC7,ATP13A2,SSBP2,HIRA,VAV2,VGF,EPM2A" Drug 3019_DN Furazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,ANK3,APAF1,NUMB,KIF1A,SCAPER,CACNA1A,CACNB2,CAMK2G,SOCS6,TAOK2,EPS15L1,CLOCK,PDE4DIP,SLITRK5,RUBCN,MAML1,DPH1,FAM13A,DLC1,ZNF589,PDLIM5,GABRA4,DISC1,GNAS,LILRA2,ITGAM,MAP4,NUMA1,GTDC1,SLC15A2,MYH15,SNAP25,WDTC1,SPTAN1,TSPYL2,ARHGEF9,ATP11A,TCF7L2,RPGRIP1L,DOCK9,KAT6B,FLRT1,PCBP4" Drug 441_DN arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "C1QTNF3,ARHGDIG,ARRB1,PDE8B,CADM3,C5,DLGAP1,CHGB,CHRNA4,DNAJB5,ARHGEF4,KLHL3,DTNA,NCALD,PIPOX,FGFR1,BAIAP2,IQCG,RUNDC3A,HPGDS,GPM6B,GPR37,GRIK5,GRM1,SOX21,NFYA,NOVA1,MASP1,PTCH1,MTMR10,SUSD4,RGS3,ATXN2,FUZ,SLA,SLC9A5,KBTBD4,SLC15A2,EMC1,POGZ,EXOC7,CDH22,ZNF74,ZNF184" Drug 3372_DN Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "RBM10,ABHD6,APBA2,APC,APOC1,SCAPER,CACNA2D2,HIPK3,EFNA3,DMTN,NCALD,ANKMY1,CAMSAP1,IP6K2,MALT1,GLS,CNTRL,GRB10,ATXN2L,DHX35,JAK2,ADAM22,NF1,PDE3B,MED1,RPS6KA2,WLS,ITSN1,SLC1A7,PPP4R3A,FAM214B,BTBD7,ZKSCAN3,ZCCHC24,IQSEC2,ATP11A,IQCE,RPGRIP1L,PSD3,CABIN1,VIPR2,KCNK12,ZNF24,SPHK2" Drug 7213_DN Vinpocetine [42971-09-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APP,CASK,KIF1A,OSGIN2,CAMK2G,CBFA2T2,STOML1,QKI,SLC4A7,CHD1L,PDE4DIP,DCAF8,RABGAP1L,DTNA,FEM1B,EPB41L1,TESK2,FOXG1,SMC2,TXNL4A,COPS8,MSL3,MAP4,MEIS1,MIA2,NUMA1,OGG1,PLEC,C1orf109,SEC61A2,ROBO1,RPS6KA2,SGK1,FERMT1,SLC15A2,SOX3,ELOVL4,FAM168A,KLHL7,RBFOX2,LMF1,NSD2,ZNF189,PCBP4" Drug 3365_DN Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AK2,AMH,AMPD3,SEMA7A,APC,FAM131A,RGS20,GYG2,CAMK2G,TAOK2,ZFYVE9,STOML1,RCHY1,PHF14,ARMCX2,MFAP3L,SGSM2,SUGP2,MBNL2,SPEG,FAM198B,SCARA3,SRCAP,GNG4,KCNJ5,KIT,SMAD1,NF1,CDK18,PLCD1,MED1,EMID1,SGK1,PPP1R9A,SYBU,AJAP1,ANKRD12,DMXL2,SZT2,PSD3,TMOD1,KCNK12,MAP3K12,DNALI1" Drug 4405_DN Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,APLP1,MARK4,CADM3,LDLRAD4,CFAP410,CAMK2B,FOXN3,PLEKHB1,TAOK2,LHX2,ZFYVE9,VAX2,CPS1,SEC14L5,RIMS3,SPOCK2,PARD6A,DRD1,ATN1,SIDT2,FHL1,DISC1,C1QL1,RUNDC3A,GLYR1,GNG4,GRM1,KCNN1,KIT,NEUROD1,MAPK7,MAPK8,RAB3A,RGS3,EMID1,SEC14L1,PEX26,SLC9A5,ZHX3,CAMTA2,EXOC7,SLC44A1,REEP1" Drug 2371_DN Lisinopril [83915-83-7]; Down 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NDRG2,ALK,APP,CDK13,ATP2B1,CAPN3,CAST,EPS15L1,RAB28,AKAP7,RCHY1,CSF1R,SIDT2,ABI2,SORBS3,FHL1,CAP2,PCYOX1,ZNF44,TRAF3IP2,HBS1L,ALDH1L1,LILRA2,GRB10,INPP1,MAP4,GIT1,RAD52,FAM184A,FAM102A,PPP4R3A,RAB3GAP1,WDTC1,SPTAN1,SRPK2,CAMTA2,THSD1,STXBP1,HIF3A,SLC44A1,KAT6B,RBFOX2,ZKSCAN5,ST7" Drug 2265_DN Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,SRPX,APOC1,PPP4R4,GYG2,SLIT2,PARD6A,DTNA,PLXNC1,USP19,GLYR1,POLL,EML4,INPP5B,VWA5A,LSS,MAP4,KITLG,MPP2,GIT1,ZNF862,NPTX1,NUCB1,NUMA1,PTN,RAD52,SEC14L1,ZNF365,PREX2,PEX26,WDTC1,ZCCHC24,KDM4C,PLCB1,THRA,TK2,TMOD1,CDK20,VAV2,SLC30A3,GDPD5,EPM2A,NUP214,RNF170" Drug 401_UP LY294002; Up 200; 10uM; ssMCF7; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NR0B1,LTBP4,AMPH,GAS7,BCAS1,PDXK,RASL11B,SLC4A4,N4BP2L1,CACNB2,HAP1,INA,CD86,CNNM1,EFNB3,LPAR6,LRRC23,EFS,FGF12,C1orf61,FOLR2,CYP46A1,STON1,HMX1,IGF1,N6AMT1,CDK14,RETREG1,MASP1,RGS4,RNH1,SYNDIG1,SEMA6D,LIMS2,NMNAT2,SPART,SSTR2,KLHL4,ACSL6,TLL2,TNS1,TRPM2,TFIP11,PMEPA1" Drug 6229_DN Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APP,BMP7,SYNJ2,OSGIN2,RAB28,CHD1L,DCAF8,KIAA0753,DNM2,USPL1,FKTN,CGREF1,SYT17,MALT1,DIDO1,AGBL5,MAP4,PMP22,STRN3,PPP3CC,RIPOR1,TMEM231,MSANTD2,PBRM1,CCDC25,TRAPPC13,SAFB,SGK1,KIF16B,ZNF430,ELMO2,INTS9,SP2,UHRF1BP1L,SS18,FCHO1,NSFL1C,DNMBP,TCF7L2,ATP13A2,CADM1,VAV1,LMF1,WIPF2" Drug 2952_UP Betulin [473-98-3]; Up 200; 9uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MRTFA,KCNAB2,CDK10,FUBP1,LDLRAD4,CBFA2T2,CDH8,CLCN4,NMT2,CSF3R,DBT,C2CD2L,DLG4,DNM2,RCAN1,PLXNC1,RASGRP2,CDHR1,AGAP2,CAMKK2,POLL,CNTRL,PADI2,AFDN,GIT1,MT1M,N6AMT1,NUMA1,CDK14,TTLL7,MRPS18A,TMEM206,GALNT10,SLA,KDM4B,ADGRL3,WWC1,EHBP1,TCF4,SZT2,OBSL1,SPHK2,ST7,KAT6A" Drug 5682_DN Niridazole [61-57-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "SLC12A5,AK2,BCAS1,CFLAR,BTRC,KYAT1,TAOK2,TPP1,PDE4DIP,MFAP3L,MED12,DRD1,RCAN1,DTNA,SORBS3,ZNF589,CINP,PRELID3A,GLYR1,GPD2,HNMT,KCNJ3,ADAM22,NEK1,NUMA1,ODF2,SERPINE2,PPP2R2B,PRPH,ZSCAN32,RALGDS,RGS10,SYBU,EPN2,BTBD7,ZKSCAN3,SOX2,ELOVL4,CEP68,ASTN2,CABIN1,EVI5,MVB12B,TIGD6" Drug 3324_DN Liothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AK2,CDC42BPA,ATM,BCL2L2,SYNJ2,RAB29,CAMK2G,CBFA2T2,ADGRG1,SLC4A8,CSF1,SIPA1L1,SDC3,DNM2,SEZ6L2,SUGP2,SORBS3,RRAGB,FGFR1,DPYSL4,FAM49B,GPR153,ELOVL5,IPO5,MAP4,NF1,SSH1,SMIM7,PPP2R5C,PRKAR1B,CEP97,ROM1,FOXRED2,SYBU,SHANK2,ZCCHC24,IQSEC2,PHLDB1,NSFL1C,CRTC1,PCDHA6,ZNF24,FTSJ1,EVI5" Drug 5666_DN Naringin hydrate [11032-30-7]; Down 200; 6.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APBB2,PPFIA3,CDK10,MADD,CFLAR,BTRC,CA4,CLGN,QKI,CSNK1E,SOCS5,FAM169A,SDC3,DAPK3,MFAP3L,DNM2,SIDT2,KIAA1109,PRELID3A,TBR1,MSL3,POLL,CNTRL,RASSF8,DHX35,KCNJ3,MPP2,ADAM22,CNOT4,SLC25A23,MED1,SNRK,WDR25,ZHX3,ANKRD12,EXOC7,TCF7,RPGRIP1L,TMOD1,VAV2,VIPR2,LMF1,ZNF74,EVI5" Drug 1388_UP Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "SYT13,PPFIA3,RIPK1,CFLAR,MTMR3,CAMK2B,LRBA,SLC4A7,CREM,CRYM,FEZ2,RIMS2,ARHGAP32,ZNF337,DBT,DPH1,ATN1,EFNB3,CEND1,MPP6,OGA,GAP43,ADAMTS13,CACFD1,MUM1,PADI2,MYO7A,OCRL,OMG,MINDY2,CNNM2,PTX3,CCDC40,RET,FAM102A,ELMO2,IGSF9B,TSPYL2,STXBP1,ANKRD12,TNS1,UBE3A,TFIP11,SLC17A7" Drug 3111_DN Iodipamide [606-17-7]; Down 200; 3.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "BRAP,ANK3,BCL7A,SYNJ2,MTMR3,LDLRAD4,ENTPD6,JAM2,ZFYVE9,IQCK,COL9A2,CREM,SLITRK5,SPOCK2,EIF4G2,DLC1,CSPG5,GAB1,GPD2,TJAP1,KCNJ5,KIT,MATK,MX1,ZNF862,P2RY1,PLCD1,MAPK8,PTN,PID1,GALNT10,SLC11A1,ZCCHC24,ARHGAP26,IQSEC2,RAP1GAP2,ST5,ARHGEF9,EXOC7,TCF7,KCTD2,PARD3,ZNF225,PRDM10" Drug 6233_UP Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASPHD1,ARID1A,NDRG2,AP2A2,GAS7,ATM,BMP7,ST3GAL5,CACNA1G,CRLF1,CLCN3,TPP1,VAX2,MFAP3L,DTNA,F3,BAIAP2,NCKAP1,ERAP1,INPP5B,ITPKB,IPO5,MAP4,ADAM22,ZNF862,NEK1,NF1,NRGN,MED1,GON4L,RNF220,NEK11,WDR47,WDTC1,ZBTB43,SEPT8,GANAB,TACC1,ANKRD12,TBL1X,PCDHA5,ZMYND8,SEMA3B,MPPE1" Drug 6277_DN Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASPHD1,ABHD6,BRAP,CDC42BPA,RIPK1,RAB29,HIP1R,SYNGR3,ZMYM4,LHX2,PLAA,CTNND2,ZNF337,GIT2,ZBTB24,RCAN1,SEZ6L2,PLEKHO1,CDKL3,F8,KIAA1109,CAMSAP1,TRMO,BTN2A1,MBNL1,NAP1L1,PC,PPP2R5C,TMEM231,ARID4A,ARHGEF10L,SEC61A2,EXD2,ROBO1,WLS,SCMH1,TMCC1,FNBP1,CABIN1,RBFOX2,LMF1,WIPF2,C12orf4,FZD3" Drug 6257_DN Cinoxacin [28657-80-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASPHD1,BRAP,CDC42BPA,APBB2,PPFIA3,MARCH3,ATP6V0A1,BMP7,SCARB1,ZFYVE9,PLAA,PPP6R2,DCAF8,LYPD1,DLG3,DNM1,DNM2,TSPAN5,SIDT2,EML1,F3,DPYSL4,PDLIM5,MSL3,GNG4,MUM1,ARHGAP19,HSF2,SETD4,SMIM7,TNPO2,POLG,RGS10,SAFB,SFPQ,RAB3GAP1,MAPKBP1,WDTC1,ELOVL4,DNMBP,TRIM2,ZMYND8,KLC2,NAV2" Drug 5236_DN LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTMR2,CAMK2G,SLIT2,NMT2,NCOR1,USP6NL,DAPK3,GIT2,MFAP3L,C2CD2L,RABGAP1L,MAMLD1,PLEKHO1,LRRC23,EZH1,FAM49B,DISC1,SRCAP,GFER,GLS,GNG4,TDRKH,CACFD1,IL6R,KCNH2,MAPT,MPP2,GIT1,FSD1,ELOVL2,RIPOR1,FAM184A,IL17RB,EPN2,BTBD7,EMC1,LHPP,THSD1,MAPK8IP3,CHST8,TRIO,FTSJ1,SEMA3B,SMIM8" Drug 2892_UP Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ASIC1,AMPD3,BIN1,APOC1,ALDH4A1,ATM,CFLAR,LDB2,ADGRG1,ZFYVE9,NMT2,DNAJB5,CNTN1,BAG4,SH2B1,NCOR2,SNCAIP,DGKG,CNIH3,SORBS3,ELAVL3,EN2,ZNF589,FOXG1,ICA1,KCNN2,AFDN,NDUFA5,CNOT4,SLC25A23,PRKAR1B,PEX5,RAB3A,MYH14,RAVER2,RPS20,STUM,ATP11A,ARHGEF12,HEY2,DAAM2,TNS1,FAM155A,ST7" Drug 4608_DN Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "GRAMD1B,APOC1,MADD,ASPH,ARHGEF1,KIAA1549L,FADS2,HOMER3,BAG4,CTNND2,KIAA0753,LYPD1,RRAGB,ANKFY1,CGREF1,SIGLEC8,NR3C1,SHISAL1,KIF5C,MAP4,NDP,NFYA,PALM,PLCD1,PPP5C,PRKAR1B,MAPK7,PTHLH,ASAP3,SLC1A7,SMARCC2,LIMCH1,TNIK,COLGALT2,THSD1,ARHGEF9,SYNE1,THRA,CABIN1,HIRA,NSD2,CLDND1,NT5M,AAAS" Drug 7288_DN Thalidomide [50-35-1]; Down 200; 15.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "NME5,BIN1,FAM131A,ST3GAL5,TAOK2,CLCN3,QKI,GIT2,ACOT8,F8,ACSL4,SCARA3,CINP,COPS8,CNTRL,RASSF8,NF1,NFIX,SLC11A2,ELOVL2,RAB3IL1,RAP1GAP,MCMBP,RPS6KA2,CLIP1,SFPQ,FAM102A,PPP1R9A,BTBD7,SMARCD3,ZBTB43,ATP11A,ROBO3,WSCD1,PSD3,ARHGEF12,BHLHB9,R3HDM1,HIRA,LMF1,XRCC4,ZNF45,EVI5,PHTF2" Drug 2932_DN Zalcitabine [7481-89-2]; Down 200; 19uM; HL60; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABAT,GRAMD1B,PLA2G6,SGCE,CAMK2G,SLC16A4,CD38,SOCS6,TMEM184B,RCHY1,EDRF1,C2CD2L,E2F5,HIPK3,ABI2,PCOLCE2,ERCC2,CD320,PTK2B,ZNF589,FECH,FER,SRCAP,GLYR1,MSL3,PSRC1,ARHGAP19,VWA5A,PIK3CD,GPSM2,PPP5C,PKN2,PTPRN2,ARID4A,PPM1E,ELMO2,TMCC1,EMC1,CEP68,TCF4,ZKSCAN5,NT5M,EPM2A,PHTF2" Drug 284_UP FK-506; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABR,RBM10,CDK10,ARNTL,ASCL1,ATP6V0A1,SCARB1,ADGRG1,CDC42BPB,C2CD2L,SMG7,ERCC2,TRMO,GLYR1,SCIN,MBD1,MYO6,NOVA1,NPR2,NUMA1,OPCML,PBX1,PLCD1,PLEC,PTPA,MAPK8,RXRA,FAM192A,AP1AR,FOXRED2,SBF1,ASRGL1,SH3BP2,NXT2,PHLDB1,PRRC2C,COBL,CABIN1,TRIO,PLPPR2,VAV2,SF1,GDPD5,FZD3" Drug 5456_UP Pinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ADCY6,AMPD3,BIN1,AMT,CNTNAP1,APAF1,NRXN1,RIPOR2,SPOCK2,DTNA,EDN1,HIPK3,EFNB3,KIAA1109,BAIAP2,GPR162,C1QL1,GNG3,NR3C1,GRM3,GUCY1A2,ICA1,KCNMA1,MEF2C,NTRK3,LRP12,PRKAR1B,PTPRH,RGS7,TCP11L1,KCNIP1,RTN1,RYR1,SHANK2,SNCA,ZCCHC24,SP4,CDK19,ATP10B,ABCC8,ATP11A,ZEB1,WNK1,KCNAB1" Drug 4571_DN Levodopa [59-92-7]; Down 200; 20.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABR,ANK3,APBB2,APP,MARK4,ADAM15,SCARB1,SYNGR3,CHM,TPP1,DNAJB5,DAPK3,FBXL5,DLG3,EGFR,ZNF589,FHL1,ANKFY1,PDLIM5,SYT17,GART,MAP4K5,AGFG1,DIPK1A,LIG4,MT1M,LYRM9,NF1,LRP12,TNPO2,SH3GL2,ASAP3,TNIK,SS18,NXT2,SYPL1,ASTN2,PDLIM2,KIAA1107,TRIM2,TNS1,TSN,SSBP2,LAT2" Drug 6221_UP Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "AK2,ADGRF5,PLA2G4C,CAPRIN2,CFAP410,ZFYVE9,ABI3BP,NCOR2,FEZ1,PDE4DIP,DBN1,DMPK,EPB41L2,VPS26C,C1orf61,PRELID3A,GAD1,HTATSF1,GPM6B,TDRKH,HSF2,KHK,PLTP,PPP2R2B,TMEM104,PTCH1,GSTCD,ZNF365,RCOR3,CDK19,ZBTB43,LHPP,MAPK8IP3,CEP68,PHLDB1,KIAA0930,AP4E1,TK2,TMPO,MICAL1,CLDND1,MAP3K12,GDPD5,SSPN" Drug 6638_UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABAT,KLRC4,KIDINS220,SYT13,AMPH,GAS7,ADAM23,MTMR3,CFAP410,CAMK2B,CDH10,DLGAP1,CHI3L2,NRXN3,RGS6,SGK2,ELAVL3,ELN,FGF1,B3GAT1,SIGLEC8,HRH3,KCND3,KCNN1,TM6SF1,MGAT3,MMP16,MSR1,MX1,PDE4B,PDGFRA,LRRN3,ZSCAN32,RGR,KCTD17,SCN2B,PEX26,BEX1,ATP10B,TACR1,DOCK9,THRA,TK2,JPH3" Drug 7202_DN Glibenclamide [10238-21-8]; Down 200; 8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "SERPINA3,AP2A2,MAP4K3,PPFIA3,BACH1,CBFA2T2,SCARB1,TAOK2,QKI,ABCG1,PDE4DIP,DZIP3,PARD6A,SUGP2,EGR3,COQ7,VPS26C,EZH1,PRKAG2,TXNL4A,COPS8,ARHGAP19,MAP4,MBD1,MTR,PC,SLC25A23,SMIM7,PPP2R5C,RIPOR1,FBXW7,SMTN,WDTC1,CLASP2,CAMTA2,ELOVL4,KAZN,EXOC7,METTL3,DNAJC12,ZNF23,MAP3K12,MPPE1,EPM2A" Drug 2277_DN Gemfibrozil [25812-30-0]; Down 200; 16uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,BEGAIN,CDK13,ALDH4A1,ATM,GYG2,ARHGAP33,CACNA2D2,RCBTB2,SOCS6,VAX2,RIMS2,JAKMIP2,TOM1,EGFR,LRRC23,FAM198B,FGFR1,FHL1,SEMA4D,JAK2,LSS,MAP4,MYT1,NRGN,CDK18,SERPINE2,MAPK8,FAM184A,RGS10,SH3BP2,FAM214B,ZKSCAN3,SNCA,KDM4B,WDTC1,TROVE2,CAMTA2,TK2,VAV2,ZFP37,ZNF24,SPHK2,SLC30A3" Drug 3_DN "1,1-dimethylbiguanide hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A" Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ABR,ALCAM,ANK2,DNAH17,ATP2B1,SYNJ2,SCARB1,MAGI1,LHX2,NIPBL,ARHGEF6,GAPVD1,INTS1,DMPK,SIDT2,MBNL2,PLEKHA1,RCAN2,GART,GJB1,KLF12,L1CAM,MBNL1,ADAM22,NF1,SMOX,C19orf57,CEP41,VPS13C,TTC13,RAB3IL1,RBBP6,STUM,ELMO2,SCN3B,SSTR2,LARP4,DIP2A,OBSL1,UCHL1,LMF1,CLDND1,SLC13A3,GDPD5" Drug 7474_UP Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "PLA2G6,ANK1,APC,APOC1,ARHGDIG,CDK13,MARK4,CFLAR,SYNJ2,GYG2,SGCE,CACNA1I,ARHGEF2,MAGI1,LY86,HOMER3,RCHY1,KBTBD11,ATN1,OPTN,DLC1,FGF12,FOXG1,SEMA4D,SRCAP,GPR37,GRB10,RNFT2,MDM4,MIA2,MPP2,NF1,PRKCB,RIPOR1,RGS12,PAQR6,SLC6A9,SLC11A1,ZCCHC24,ZBTB43,LHPP,SLC44A1,TMOD1,MICAL1" Drug 1545_DN Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ARID1A,AP2A2,OSBPL1A,PLA2G6,APLP1,PPFIA3,ST3GAL5,BTRC,CFAP410,CA12,CBFA2T2,SULT4A1,CSNK1E,RUSC2,DYRK1A,FER,SRCAP,RAB30,KCNMB4,GRB10,ATXN2L,MAP4,MSI1,NPTX1,NTRK2,PDE3B,PLTP,LRP12,PPP2R5C,PRKAR1B,PRPH,ATG16L1,RYR1,PKNOX2,SLC9A5,KDM4B,WDTC1,CAMTA2,ARC,FBXW11,TCF7L2,ZNF34,TRPC1,TRPM2" Drug 3094_UP S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "KCNAB2,ZSCAN18,ATP2B2,SEPT7,NRG2,SH2B1,ARHGEF10,KIAA0513,DLG4,EEF1A2,FCF1,OLIG2,DLC1,SORBS1,CHL1,ERAP1,SIGLEC8,HPGDS,PRUNE2,RAPGEF1,KCNJ5,KHK,GIT1,SNTG1,PENK,CCSER2,PURG,RELN,PTPRN2,RIPOR1,RGS10,SMTN,ZSWIM8,KDM4C,ZC3H13,RAP1GAP2,ST5,SEPT8,RPGRIP1L,AMACR,VSNL1,MAP3K12,STMN4,FZD3" Drug 1826_UP Thiamphenicol [15318-45-3]; Up 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APAF1,APC,ASPH,MPDZ,SYNJ2,MAP7,SOCS6,ZFYVE9,CLTB,QKI,PICK1,PREPL,VCAN,PDE4DIP,MATR3,E2F5,EDNRA,APH1A,ELAVL2,FECH,GAD1,ERAP1,ARFIP1,EML4,RNFT2,HMGCR,INPP5B,ARHGAP12,CNOT4,NOVA1,BSDC1,ZNF671,ST6GAL1,CCDC88A,EMC1,ARHGEF9,TCF7,TCF7L2,METTL3,HIRA,NSD2,XRCC4,EVI5,PDSS2" Drug 7265_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "MTUS1,MARK4,ALDH7A1,MYRF,ARHGEF2,TAOK2,LHX2,ZFYVE9,RAB26,CNTNAP2,HDAC9,SNPH,ARMCX2,RUSC2,EFNA3,MBNL2,PLEKHO1,LRRC23,NRN1,F3,REEP2,FGF13,OGA,ZNF274,NCKAP1,GLRB,CNTRL,SCIN,DIPK1A,MAPT,MGAT3,RETREG1,CNNM2,MAPK12,SCN8A,PPP1R9A,FAM214B,TNIK,CAND2,SS18,CEP68,WWC1,HPS4,KCNAB1" Drug 4478_UP Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "ANK2,APC,CDK13,CCDC181,NRP2,KSR1,CACNA1G,LDLRAD4,TAOK2,DNAJB5,NCOR2,ARHGEF10,VCAN,MFAP3L,CDON,EDNRA,NCALD,FYB1,FYN,SPACA9,GRM1,GRM8,GUCY1A2,ITGA7,KCND3,KCNF1,NOVA2,PDE3B,PROX1,DCHS2,ZSCAN32,KHDRBS2,RGS10,RGS12,SLC11A1,SNAP25,KIF21B,TSNAXIP1,KLHL4,TK2,LAT2,ZNF711,KCNAB1,TIGD6" Drug 2072_UP Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APBB2,SEMA4G,SLC4A4,ADAM23,SCAPER,PLEKHB1,NRXN3,CLCN3,ABCG2,ABCG1,DCAF4,FCF1,COQ7,CDKL3,CINP,SIGLEC8,GCNT2,GPR17,GRIK5,KIF5C,LMO2,MEIS1,MMP16,MX1,NDUFA5,NEK1,PALM,PPP2R5C,APTX,GAL3ST4,EMID1,TRAPPC13,IL17RB,SH3BGR,PPP1R9A,RAP1GAP2,CEP68,RGL1,EHBP1,KIAA0930,PSD3,ZNF711,MAP3K12,EMSY" Drug 1763_UP Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "RBM10,APC,CDK10,SEMA4G,ARRB2,BAIAP3,CA12,COL9A2,SEC31B,PARD6A,EXOG,RBM12,ING4,DMTN,GPHN,ZNF589,SEMA4D,CAMKK2,GALC,NEU3,SRCAP,TXNL4A,TJAP1,MAP4,NEFH,NOS1,PIK3R1,PLCB2,CNNM2,RAB3A,RAP1GAP,NUBPL,INTS9,DOP1A,ERC1,EHBP1,TLR4,TMOD1,TNS1,TP53BP1,ZKSCAN5,SMIM8,NUP214,AAAS" Drug 4693_DN Kawain [500-64-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 8.91E-03 1.00E+00 4.27E-02 4.86E-01 44 197 "APBB2,RGS20,ALDH4A1,KIF1A,BTRC,ARHGEF2,LHX2,AKAP7,SLC4A8,ARHGEF4,PPP6R2,CTIF,BRINP1,RUSC2,DNM1,ATN1,DTNA,AASS,FHL1,SEPT9,MSL3,GNG4,GRM8,MAP4,NEUROD1,NPTX1,MAPK7,TRAPPC13,SH3BP2,FUZ,KIF13A,SOX2,ZCCHC24,TROVE2,MAPK8IP3,ATP11A,ZEB1,THRA,TSC1,VGF,XRCC4,DNALI1,EVI5,KCNAB1" Drug ctd:C010176 halofuginone CTD 9.01E-03 1.00E+00 4.32E-02 4.91E-01 31 129 "SPARCL1,PROM1,USP2,B4GALT6,CP,AKAP12,DBN1,EDNRB,ELN,PTK2B,FGFR3,DKK3,GATM,GYG1,HSD17B1,IGFBP1,ITGA7,CD200,TAGLN3,FXYD6,NFE2L2,PDGFRA,PKM,PMP22,PTPRD,NLGN1,SPP1,TCF4,VSNL1,CLIP2,SLC13A3" Drug ctd:D004121 Dimethyl Sulfoxide CTD 9.03E-03 1.00E+00 4.33E-02 4.93E-01 70 339 "BEND6,SLC24A4,AMT,ATP1A2,ATP1B3,CFLAR,AIFM1,CD38,CDC25B,RAB3C,SLC24A2,DNAJB5,COL4A5,COX4I1,CP,CS,CSF1R,CTH,PARD6A,EDNRA,EDNRB,EIF4G2,TUBB3,EFEMP1,FLNC,CGREF1,GAD1,GJB1,GPR75,GNG3,SERP2,SLC2A6,HP,ICA1,IL12A,ITGAM,JAK1,MAT2A,MEF2C,MSRA,MYBPC1,LYRM9,MYH6,NEFH,NFE2L2,ENPP2,PGAM2,ABCB1,C11orf49,PPARA,MAPK3,PRPH,RELN,LAMA1,REV3L,RFX3,PGBD4,RXRA,RXRG,TRA2B,CXXC4,GLT8D1,LRRC4,APOM,TMEM150C,TF,TMEM121,TJP1,TPM3,CADM1" Drug CID006439899 agelasine B Stitch 9.06E-03 1.00E+00 4.34E-02 4.94E-01 14 46 "ATP2A2,ATP2B1,ATP2B2,ATP2B3,CCK,CCKBR,CHGA,EPHB1,ATP2C1,MBP,PKD1,MAPK3,GPR161,TK2" Drug CID000006989 thymol Stitch 9.06E-03 1.00E+00 4.34E-02 4.94E-01 14 46 "RUNX1T1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GPT2,KCNMA1,MAT2A,RYR1" Drug CID000000964 hydroxypyruvate Stitch 9.06E-03 1.00E+00 4.34E-02 4.94E-01 14 46 "ALAD,LDHD,PNKD,CS,GATM,PTPN5,HPSE2,HP,HPR,OGDH,PC,APTX,SHMT2,NPL" Drug CID000050614 Cefotetanum [inn-latin] Stitch 9.06E-03 1.00E+00 4.34E-02 4.94E-01 14 46 "ATM,CACNA1A,CACNA1E,NGB,GSDME,ATN1,GAA,TRAF3IP2,HBA1,FSD1,RBFOX2,RASD2,TTPA,UGT8" Drug CID000004548 NPC 15437 Stitch 9.06E-03 1.00E+00 4.34E-02 4.94E-01 14 46 "ADCYAP1R1,CAMK2B,CAMK2D,LRBA,GRIA1,GRIK1,GRM2,HTR2A,PRKACB,PRKCB,PRKCG,PKN2,PRKCZ,VIPR2" Drug 3902_UP Withaferin A [5119-48-2]; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.10E-03 1.00E+00 4.36E-02 4.96E-01 40 176 "BEGAIN,AMPD3,BIN1,APAF1,PPFIA3,RGS20,NRP2,CAMK2B,CLCN3,CREM,CNIH3,RABGAP1L,EN2,LRRC23,CEND1,KIAA1109,BAIAP2,GATM,GRB10,IL6R,KCNMA1,MBP,SERPINI1,PLTP,LRP12,NECAB2,MINDY2,CEP41,MAPK7,PTPRH,MORC4,RPS6KA2,CLIP1,SLC6A9,JMJD6,TBCEL,OBSL1,VLDLR,SLC30A3,KCNAB1" Drug CID000007019 9-aminoacridine Stitch 9.12E-03 1.00E+00 4.37E-02 4.97E-01 21 79 "ACHE,ARRB1,ARRB2,CBS,CHRDL1,RASA4,POLK,GPR153,GRIN2C,HNMT,LRRC4B,POLG,REV3L,SARS,ARFGAP1,DDN,ADHFE1,SMG6,SYNE1,SPX,WNK1" Drug 2937_DN Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "ABAT,NDRG2,PKP4,SLC4A4,FUBP1,CAMK2G,CD86,CBFA2T2,CDC42,RCBTB2,RAB33A,ZFYVE9,SLC4A7,PDE4DIP,GPRASP1,ZFYVE16,OPTN,MBNL2,ING4,VPS13B,LRRC23,RASGRP2,GABRA4,ADAM28,RND1,GLYR1,CACFD1,IL11RA,MAP4,PCDH9,ENPP2,PENK,MINDY2,SBF1,SLC15A2,TSPYL2,STX1A,DNMBP,KIAA1107,TBL1X,TPM1,PHTF2,NLRP3" Drug 4274_DN Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "MTUS1,CFLAR,SPAG9,KRIT1,FAM169A,PHF14,PUM1,ARHGAP24,DBT,SMG7,FCF1,ETV1,BAIAP2,ATP2C1,AGFG1,IFI16,IL6ST,JAK2,MAP4,TM6SF1,NUMA1,OPA1,SNX10,STRN3,PPM1B,PPP3CC,PRKAB2,SLC25A36,GSTCD,FBXW7,AP1AR,FBXO11,THSD1,CEP68,ZC3H4,PSD3,DICER1,TK2,TMPO,SF1,ZBTB38,PRDM2,EVI5" Drug 5990_DN Thalidomide [50-35-1]; Down 200; 15.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "ASPHD1,APC,PPFIA3,PDE8B,ASPH,CFLAR,SYNJ2,SCAPER,C5,BTRC,AKAP7,NCOR1,FEZ1,MICAL2,PDE4DIP,FAM169A,GREB1,ANKMY1,KAT8,FGFR1,FHL1,IL6R,SLC25A23,PRODH,SAMD9,PTK2,TMEM231,SUSD4,RXRA,PPP4R3A,SLC20A2,ZHX3,EMC1,IQSEC2,ASTN2,AHCYL2,CHST8,TRPC1,LMF1,XRCC4,ZFP37,MAP3K12,HPS4" Drug 2766_DN Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "CDC42BPA,ARRB1,SLC4A4,STX16,CFLAR,SPAG9,CREM,PDE4DIP,TM9SF4,DAPK3,DTNA,FCF1,KAT8,ZNF589,GART,GLYR1,GRB10,TJAP1,INPP5B,MDM4,KITLG,NF1,NFYA,SLC11A2,NUMA1,ODF2,PIK3R1,PLEC,PPP5C,PEX5,ATG16L1,FNDC3A,PEX26,RAB3GAP1,ELMO2,NXT2,PLCB1,DICER1,KAT6B,CLDND1,EVI5,PHTF2,FXR1" Drug 1562_UP Pimozide [2062-78-4]; Up 200; 8.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "NDRG2,AP1B1,APBA2,GAS7,CACNA1A,CAST,CLDN10,KRIT1,SRSF11,FOXN3,CNTFR,SLC4A7,RNF14,PPP1R16B,RIMS2,ZFYVE16,CTIF,MED12,ELN,PLEKHO1,ETV1,ANKMY1,AFF2,GPR153,PCDH17,RUNDC3A,OS9,NELL2,SLC11A2,PLCB2,MBOAT7,CNNM2,RAB3IL1,KHDRBS2,TRIM68,SGK1,CCDC88A,HECW1,SPART,ZFR2,AHCYL2,XRCC4,WIPF2" Drug 1271_DN N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "OSBPL1A,ANK2,CDK13,N4BP2L1,BCL7A,MTMR2,CBS,ENTPD6,HOMER3,PREPL,PPP6R2,HDAC4,ZNF337,CTIF,DTNA,PCOLCE2,DENND4A,GART,CRCP,LILRA2,HSF2,INPP5B,ODF2,ZFYVE21,C1orf109,ARHGEF10L,ATXN1,AMBRA1,URGCP,CCDC88A,CLUAP1,TSPYL2,CLASP2,SS18,NXT2,GSE1,TCF4,TLR4,TMPO,TNNT1,NSD2,WRN,REEP1" Drug 458_DN 2-propylpentanoic acid; Down 200; 1000uM; PC3; HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "RBM10,ACTN1,NDRG2,BCAR3,RUNX1T1,CLTA,CREM,SIPA1L1,DCAF4,TM9SF4,G3BP2,EIF5,ELAVL4,COQ7,HPCAL4,IP6K2,TRAF3IP2,ARFIP1,BTN2A1,HAS2,NEK1,KCTD15,PLEC,VPS13C,SH3TC2,SUSD4,PCMTD2,ZC3H14,CASC3,SON,ZHX3,SP2,HECW1,EXOC7,TCF7L2,KAT6B,METTL3,TRIO,WIPF1,SF1,SLC17A7,FIP1L1,CAMK1G" Drug 6254_DN Methantheline bromide [53-46-3]; Down 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "ASPHD1,KIDINS220,MARCH3,NUMB,ATM,CFLAR,PLAA,COL4A5,ABCG1,CSNK1E,SOCS5,DZIP3,SMG7,VPS26C,ANKMY1,F3,PDLIM5,ERAP1,COPS8,GNG4,AGBL5,MBD1,MITF,PMS2,LRRC49,ZSCAN32,PEX5,SEC61A2,RXRA,RAB3GAP1,WDTC1,SPTAN1,ZBTB43,ASTN2,MCF2L,TCF7L2,TRIM2,NR2C2,ZMYND8,HIRA,XRCC4,UPF3A,WIPF2" Drug 485_UP deferoxamine mesylate salt; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "PPFIA4,CADM3,GYG2,CACNA1I,FOXN3,AATK,FEZ2,SIDT2,EFNA3,SORBS3,ENO2,DLC1,FLNC,FOLR2,GAP43,TMEM8B,AHDC1,LILRA2,BTN2A1,KLF12,HSF2,KCNB1,L1CAM,MYO7A,PFKFB3,SMOX,RNASEL,TCP11L1,SH3BP2,CDK5RAP2,SMARCD3,KDM4B,KDM3A,POPDC3,ANKRD12,WSCD1,SEZ6L,TMPRSS5,PLPPR2,SLC13A3,ZBTB14,ZNF189,KCNAB1" Drug 2865_DN Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "EPB41L5,MTMR2,BTRC,KRIT1,CDC27,QKI,RCHY1,ENTPD4,AKAP12,PPP6R2,MFAP3L,DTNA,SORBS3,VPS13B,PDLIM5,PSRC1,GPR37,CNTRL,ARHGAP19,HSD17B1,IL6ST,BRINP3,INPP5B,KCNJ3,KITLG,NF1,PCDH9,PIK3R1,GPSM2,MAPK8,SPDL1,GSTCD,CLIP1,SMTN,ELMO2,SLC20A2,PDZRN3,MAPK8IP3,STX1A,PSD3,TRIO,VGF,PHTF2" Drug 2123_UP Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "RALGAPA1,ANK1,ATP2A2,KRIT1,LARGE1,SOCS6,ZFYVE9,CPS1,PLEKHO1,LRRC23,ANKMY1,FGF1,TRMO,DLL3,B4GALNT1,SYT17,PCLO,CLASRP,BACH2,HSF2,INPP5B,KCNN1,SMAD1,PDE4D,MINDY2,PRPH,FAM120C,FAT4,GAL3ST4,AMBRA1,DOP1A,ZHX3,IQSEC2,COLGALT2,IQCE,FBXW11,SYNE1,HIRA,UGT8,WNK1,EMSY,SEMA3B,PHTF2" Drug 3460_UP Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "ACTN2,PLA2G6,C1QTNF3,APAF1,KCNAB2,GAS7,ARHGDIG,RIPK1,SCAPER,GYG2,ABCG2,ENTPD4,CSF1,VCAN,EDRF1,RIMS3,EGFR,CAMSAP1,FHL1,MPP6,RND1,MSL3,STON1,GSN,KCNJ5,MAP4,MSI1,NEK1,SLC11A2,PCDH9,RAD52,ZDHHC14,GTDC1,BTBD7,SNCA,ZHX3,KDM4C,IQSEC2,ROBO3,EXOC7,TCF7L2,SZT2,TFIP11" Drug 6808_DN Estropipate [7280-37-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "NDRG2,MTUS1,APC,ALDH4A1,SYNJ2,CACNB2,CDC42,FOXN3,ASIC3,VAX2,ARHGEF6,BAG4,CSF1R,FAM169A,RIMS2,SLC12A6,EIF4G2,ING4,TNK2,LRRC23,GLS,GNG4,IL6ST,KPNA5,MAPT,MDM4,STRN3,PPP5C,PRPH,ATG16L1,RGS3,RGS12,NEK11,CNKSR2,PREX2,ZKSCAN3,SNCA,SAMSN1,STX1A,PLCB1,TBL1X,EPM2A,SSPN" Drug 7248_UP Triprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "MRTFA,LGR5,BACH1,SCARB1,CLCN4,AKAP12,PDE4DIP,E2F5,SGK2,MBNL2,F3,ACSL4,DLC1,BAIAP2,AMOTL2,SHISAL1,DIPK1A,ITGAV,KIF2A,MEF2C,AFF1,MX1,PDE1C,EPN1,TNPO2,PTX3,MRAS,DOCK10,ZNF667,SMARCD3,RAP1GAP2,ERBIN,ELOVL4,VPS13A,SYT1,WWC1,SYNE1,TRIO,RUNDC3B,NSD2,NAV3,PHTF2,ACTR3B" Drug 960_UP 5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "BIN1,APC,ASPH,ST3GAL5,SRSF11,CNOT8,PLAA,ABCG2,LRIG1,SDC3,ARHGEF4,FBXL5,SMG7,SGSM2,TRAPPC9,DSCAM,DTNA,SIDT2,SCML2,POLR1B,SEMA4D,ANKFY1,OGA,GRB10,ATXN2L,LIG4,MITF,NF1,NFYA,TNPO2,ZSCAN2,TMEM231,WDR47,SHANK2,KDM4C,PLCB1,ASTN2,MTCL1,PCDHA6,AHCYL2,RBFOX2,LMF1,ST7" Drug 1076_UP "ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "ALAD,EPB41L5,ARNTL,CDK13,NCOA1,ATM,BCL7A,CFLAR,SYNJ2,REPS2,CLCN3,RAB26,MFAP3L,FBXL5,MED12,DTNA,TSPAN5,MBNL2,SORBS3,CDKL3,IP6K2,FAM49B,B4GALNT1,MUM1,BRINP3,ITGAV,MAP4,AFF1,PMP22,STRN3,PPP3CC,SYTL2,ARID4A,ZNF821,SUPT20H,AMBRA1,ABLIM3,ARFGAP1,SMARCC2,RCOR3,CLSTN2,TRIM2,TPM1" Drug 4217_DN Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "CDC7,MTUS1,ANK3,SHROOM2,ATM,OSGIN2,B4GALT6,SMARCAL1,SLITRK5,SNPH,TBC1D5,GIT2,ZBTB24,RHOBTB1,DENND4A,F8,DENND2A,GPER1,HNMT,DIPK1A,LIG4,TM6SF1,MIA2,NDP,PAK3,PLCD1,PTCH1,PTN,ZSCAN32,PTPRE,ATG16L1,AP1AR,FBXO11,ANKRD6,ZNF365,GLT8D1,FAM208A,AHCYL2,TNS1,XRCC4,HPS4,KCNAB1,PLSCR4" Drug 3635_UP Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.18E-03 1.00E+00 4.39E-02 5.00E-01 43 192 "LTBP4,MRTFA,ANK1,KCNAB2,APOC1,RGS20,PDE8B,ADAM15,WHRN,CREM,CSF1,DTNA,MBNL2,EGR3,ELAVL3,OLIG2,ERCC2,FABP7,PTK2B,KIAA1109,RND1,PCLO,GRB10,IL6ST,INPP5B,ITGA7,KCNN1,MAN2A2,ZNF862,POU3F4,ELOVL2,RNASE1,SLC6A9,SLC11A1,MAPK8IP3,VAMP1,SYN2,ATP11A,ROBO3,TRIM2,ZFPM2,VLDLR,CLDND1" Drug CID006324619 Compound-1 Stitch 9.24E-03 1.00E+00 4.42E-02 5.03E-01 29 119 "ACHE,PDZD4,AP4M1,LRBA,CDC25B,BOC,HDAC9,DMPK,EDIL3,EDN1,RCAN2,AHCYL1,GART,GPR12,MCHR1,HPS5,HRH3,ASPRV1,CCDC80,NASP,ABCB1,PRKACB,PSMA6,PTPN13,ROM1,WDTC1,SYNE1,GPR161,SPHK2" Drug ctd:D003999 Dichloroacetic Acid CTD 9.26E-03 1.00E+00 4.43E-02 5.04E-01 184 996 "VWA5B2,SERPINA3,ACADM,ABHD6,NCKAP5,CCDC85A,ZNF608,SNX32,SPARCL1,C1QTNF4,ABCD2,UNC79,GPAM,APOC2,ASPA,ATP1A2,N4BP2L1,BARD1,LDHD,C5,CAPN3,PRC1,USP2,DLGAP2,CACNA2D2,CIART,CHRNA4,CHRNB2,ZBED5,ABCG2,DNAJB5,CCDC151,IQCK,ANKRD35,GAL3ST1,FAM171B,HAPLN1,MROH8,PITPNM3,NOS1AP,KATNAL2,TOX,SCRN1,CTIF,BRINP1,DBI,DCT,RPS6KL1,NR1D2,ACOT8,RCAN1,DUSP9,SNX29,SGK2,EFNA2,CDKL3,ANKMY1,F3,F5,REEP2,ACSL4,PPP1R1B,SPSB4,FOXM1,SYT3,SDCBP2,GABRB3,GAD2,MSTN,GPR162,MMADHC,PPARGC1A,RAB30,GPD1,GPD2,GPR12,B4GALNT4,MCHR1,GRIA1,PLCD4,GRID1,GSTT2,MFSD2A,FAM107A,FAM222A,WIF1,HBA1,ELOVL5,SYNPO,IFI16,IGFBP1,NIM1K,IL6R,LRRTM3,SLC35G1,LRRC4B,LIFR,PACRG,ADAM11,MID1,NRBP2,CTNNA3,MX1,MYBPC1,MYCN,NCAM2,RCOR2,NFE2L2,NME4,NOS1,NPTX1,NUCB2,TBC1D25,GPR88,OLR1,P2RY1,PDE4D,GPR173,SERPINE2,SEMA5B,ANLN,SMOX,PSAT1,PPARA,MAPK10,FITM2,SPDL1,ACSS3,FAM184A,VEPH1,FIGN,RFX4,RGS4,RLBP1,NEK11,MEG3,HUNK,CCDC112,TNFRSF19,SMPD3,IL17RB,SYBU,FAM81A,PKNOX2,SLC6A7,SLC8A1,SHANK2,TMEM132D,EFHD1,SORCS3,SNCA,IZUMO4,UNC5B,PEG10,SPTB,TSPYL2,NFASC,SSTR1,STAC2,SULF2,SYT4,ATP11A,DDHD2,DNMBP,TBCEL,TMEM136,TNS2,HIF3A,TF,ENHO,BHLHB9,LRRC24,NEIL2,FNDC5,UBC,CCDC136,VLDLR,SLC13A3,FMN2,ZBTB16,SLC30A3,CERS6,PIANP,NETO2" Drug CID002733484 capsazepine Stitch 9.28E-03 1.00E+00 4.43E-02 5.05E-01 22 84 "ASIC2,ASIC1,HCN2,CACNA1A,CACNA1B,CACNA1D,CACNA1E,CACNB2,CBS,ASIC3,CNR1,FOXM1,B3GAT1,CRCP,KCNJ4,NOS1,HCN1,PRKCB,SCNN1D,TAC1,TAC3,TACR1" Drug CID000045285 dioxamate Stitch 9.33E-03 1.00E+00 4.46E-02 5.08E-01 17 60 "MYOM2,CDO1,TPP1,CNGA3,FOLH1,MYH7,NEFM,NEFH,NOS1,PRPH,SLC1A2,SLC1A3,SNCA,SYP,ZFP91,TRH,UBC" Drug CID000000049 alpha-ketoisovalerate Stitch 9.38E-03 1.00E+00 4.49E-02 5.10E-01 23 89 "NUMB,CALM1,CAMK2B,CAMK2D,KRIT1,NUMBL,CS,DBT,SH3GLB1,CAMKK2,CAMK2N2,OGDH,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,NSD1,KAT6B,KAT6A,NUP214" Drug CID000003372 fluphenazine Stitch 9.44E-03 1.00E+00 4.51E-02 5.14E-01 24 94 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1B,CALM1,KRIT1,CDR1,ASIC3,CHRM1,CALN1,DRD1,DTNA,ZMYND10,HTR2A,HTR5A,KCNN3,PPP3CC,EPDR1,SCN4B,SCN3B,SST,SYN2,TAC1" Drug CID000170612 Asp-pro Stitch 9.45E-03 1.00E+00 4.52E-02 5.14E-01 26 104 "AP2A1,AQP4,AQP6,NGB,HIP1R,REPS2,EPS15L1,CLTC,APPL1,SNAP91,DNM1,DNM2,DNM1L,STON1,HBA1,INPP1,MATK,PDCD2,EPN1,PYGM,SCN2A,ASRGL1,SH3GL3,SNAP25,SYP,SYT1" Drug CID006368594 AC1OC6D1 Stitch 9.45E-03 1.00E+00 4.52E-02 5.14E-01 26 104 "ALCAM,CHRM1,NCOR1,HDAC9,FOXM1,GLRB,STMN2,GRIA2,GRIN1,L1CAM,SCP2,TRA2B,SLC11A1,SMARCA4,SMARCC2,SMARCE1,SCN3B,SP4,SYN1,SYP,TCF4,GPR161,THRA,TK2,CBX5,SCG2" Drug 2684_UP trifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.46E-03 1.00E+00 4.52E-02 5.14E-01 42 187 "MTUS1,ASPH,ATP2B1,BACH1,NRP2,NRG2,CREM,CSF1,VCAN,PDE4DIP,DZIP3,USP6NL,ZNF337,ATN1,RCAN1,MBNL2,EGR3,F5,PRKAG2,CAP2,PDLIM5,GABRA2,LYVE1,GNAS,STON1,GRIK5,KCND3,MID1,MOBP,OLR1,PDE1C,ENPP2,MAPK7,RALGDS,SGK1,SLC11A1,SPP1,ANKRD28,PHF24,TGFBR3,ZBTB38,SLC17A7" Drug 2671_DN retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.46E-03 1.00E+00 4.52E-02 5.14E-01 42 187 "ADRB2,KIDINS220,TRMT9B,NUMB,C5,CACNA1A,MICAL2,CSNK1E,VCAN,CTNND1,DOCK4,TRAPPC9,DTNA,ELN,MTSS1L,FHL1,CAP2,CAMKK2,FYN,ZNF44,SEPT9,COPS8,POLL,ACOT7,KIF2A,MAP4,TM6SF1,MGAT3,SLC11A2,PLEC,SYTL2,SIDT1,PTX3,ARHGAP26,DDN,ANKRD28,TBL1X,ZEB1,SSBP2,XRCC4,NAV3,TIGD6" Drug CID000131516 alpha IMGBL Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000131164 OPC 3911 Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ALDH7A1,CIT,PDE1C,PDE3A,PDE3B,PDE1B" Drug CID000000017 "2,3-di-H-dipicolinate" Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "AASS,QDPR,HOGA1,PBLD,THRA,NPL" Drug CID000126323 1-methylisoguanosine Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,GPR162" Drug CID000003398 flutazolam Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000431902 NSC299933 Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ACHE,BRAP,AMPD2,AMPD3,RYR1,RYR3" Drug CID000121964 A71623 Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "CALM1,CCK,CCKBR,KRIT1,BOC,TAC1" Drug CID000443225 AC1L9E9N Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "WASF1,CS,F5,STON1,TRERF1,CYB561A3" Drug CID000164437 HENECA Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ADARB2,ADORA1,ADORA2A,ADORA3,APPL1,NPPA" Drug CID003707225 AC1MVFYM Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID003081502 nitinol Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "CNOT8,CLU,NEGR1,POU3F4,ABCC8,AAAS" Drug CID000536683 oxazolidine Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "BOC,PPP1R1A,PTAFR,SALL1,SYNE1,RASD2" Drug CID000008554 dimethyl phthalate Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "DMPK,DMTN,POLK,KCNH1,CARF,TP53BP2" Drug CID003080722 3-aminopyridine adenine dinucleotide Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "CD38,GPD1,GPD2,NBL1,ADHFE1,CYB561A3" Drug ctd:C060311 eckol CTD 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "PROM1,CYBB,FOXO3,MSI1,MAPK3,SOX2" Drug DB00151 L-Cysteine Drug Bank 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "CARS,NFS1,CBS,CDO1,CTH,SLC19A3" Drug CID000008081 trioxane Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "TOX,EYA1,HNMT,SLC6A1,SYNE1,HPS4" Drug CID000071272 metaclazepam Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID005488302 harmol sulfate Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ABCG2,ABCC5,CNTN3,ABCB1,SLCO1A2,MCF2L" Drug CID000004401 N6-cyclopentyl-9-methyladenine Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ADAR,ADARB2,ADORA1,ADORA2A,ADORA3,CNR1" Drug CID003037058 fluoresceinthiocarbamylethylene diamine Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "APPL1,STX2,SLC11A2,SLC6A7,STX1A,ST8SIA2" Drug CID000189112 tetrahydroisoquinoline carboxylic acid Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ARNTL,BOC,DMTN,CRCP,PDYN,SST" Drug CID000001467 AC1L1BJN Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "ADCY5,ADCY6,ADCY8,ADORA1,ADORA2A,F3" Drug ctd:D000376 Agmatine CTD 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GFAP,GRIN1,GRIN2C,GRIN2D,MBP,SLC47A2" Drug CID000065875 nerisopam Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID003033621 cinolazepam Stitch 9.49E-03 1.00E+00 4.52E-02 5.15E-01 6 13 "GABRA1,GABRA2,GABRA4,GABRA5,GABRG1,GABRG2" Drug CID000205489 TG-3 Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "AGAP2,GRIA1,GRIK1,GRIK4,GRIK5,GRM1,GRM2,GRM3,GRM5,GRM8,TRPC1" Drug CID000477669 AC1L9XAW Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "ADORA3,CACNA2D1,NPIPA1,BOC,POLL,MAOB,MX1,PMP2,PTPA,PYGM,SYNE1" Drug CID000005392 temephos Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "ACHE,AXIN2,BLM,CACNA1A,BAG4,STAG2,AHDC1,KCNA1,KCNA2,RAD51D,SLC1A3" Drug ctd:D006160 Guanosine Triphosphate CTD 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "AGT,APP,CDC42,CSF1,GNAS,GUCY1A2,GUCY1A1,GUCY1B1,HRH3,ABCB1,RAB3A" Drug CID000446336 AC1L9JJ0 Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "CDK10,ASPA,ATM,EFS,GAA,MAG,MXI1,PAH,RET,NSFL1C,UGT8" Drug CID003330140 Px A Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "EGFR,GFAP,NEFM,NEFH,NF1,SERPINE2,PTCH1,ROM1,SYP,SMUG1,TSC1" Drug ctd:D010972 Platelet Activating Factor CTD 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "AGT,CX3CR1,EDN1,EDNRB,ITGAM,OLR1,PPARA,PTAFR,RGS4,SELL,TIMP4" Drug CID000003182 dyphylline Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "ADRB2,PDE8B,PDE1A,PDE1C,PDE2A,PDE3A,PDE3B,PDE4A,PDE4B,PDE4D,PDE1B" Drug CID000107968 S-methyl-L-thiocitrulline Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "BRAP,AGT,CBS,CCKBR,CNR1,FOXM1,GRIK1,NOS1,OXTR,MAPK3,TACR1" Drug CID000124912 disuccinimidyl tartarate Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "CSF2RA,EDN1,EDN3,EDNRA,EDNRB,GALR1,LSS,KITLG,RIT2,TAC1,ST8SIA2" Drug CID000071333 AC1L2FYN Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,KCNMA1,TPM3" Drug CID000370232 CA4P Stitch 9.60E-03 1.00E+00 4.57E-02 5.20E-01 11 33 "CA4,HEPH,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug 7422_UP Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.74E-03 1.00E+00 4.61E-02 5.24E-01 41 182 "SEMA6A,BIN1,ANK3,APBB2,SEMA4G,CDK13,BAG4,ENTPD4,PPP6R2,GIT2,TMCC2,DLG3,DRP2,MBNL2,EIF5,VPS26C,ZNF589,FHL1,FAM49B,CAMKK2,SYT17,GRB10,NR3C1,RNFT2,SLC2A6,HMGCR,MBD1,MIA2,LYRM9,SERPINE2,RIPOR1,SYBU,PLCB1,TCF7L2,TRIM2,THRA,RBFOX2,ZNF45,MAP3K12,GDPD5,SSPN" Drug CID000349960 Sialic acids Stitch 9.74E-03 1.00E+00 4.61E-02 5.24E-01 68 329 "SERPINA3,LRRC7,SPOP,AMH,OGT,ST3GAL5,CANX,COG1,CLU,CLTA,COL11A2,RCHY1,CP,VCAN,NTM,GNE,ST8SIA3,EEF1A2,VPS13B,EPB41,STX2,ST3GAL6,ST6GALNAC3,OGA,CHL1,B4GALNT1,GAP43,SIGLEC8,NEU3,GCNT2,GGT7,GGT5,POLL,GNAS,GPR22,HP,HPR,KCNA1,IPO5,L1CAM,LAMP2,LSAMP,MAG,MGAT3,MOBP,MOG,GIT1,NCAM1,NCAM2,OMG,ST8SIA5,TNFRSF19,SELL,FNDC3A,ST6GAL1,BCAN,NLGN1,ST3GAL3,ST8SIA1,CCDC88A,EPB41L3,ADGRL3,NEU4,TF,NPL,SIGLEC10,NELFE,ST8SIA2" Drug 6346_UP Sulfasalazine [599-79-1]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASPHD1,ARID1A,NDRG2,ADORA1,AMT,ALDH4A1,CACNB2,SCARB1,NEURL1,SEPT7,CLCN4,PICK1,CNTFR,AKAP7,HINFP,CSNK1E,DZIP3,DMPK,EDIL3,EZH1,CGREF1,PNMA2,DISC1,NEU3,GFER,GLYR1,PRRC2B,LPAR4,SCIN,ITPKA,MDFI,PLCD1,FSD1,CNTLN,RAD52,C1orf54,TCP11L1,STUM,DZIP1,IFT122,SCN3B,LHPP,CEP68,R3HDM1" Drug 1846_DN Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,PPFIA1,APP,CFLAR,SYNJ2,LDLRAD4,SLC25A14,RUBCN,DBT,SGSM2,DNM2,DTNA,SUGP2,EPB41L2,COQ7,CD320,FCGRT,GALC,ARFIP1,SESN1,HNMT,NFYA,ODF2,OGG1,PDE4B,PDPK1,GPR85,PTPA,DEF8,RAD52,GTDC1,RGS10,RAB3GAP1,ZCCHC24,SS18,MLC1,PDLIM2,TBL1X,TCF7,SZT2,THRA,ZNF32,HPS4,URM1" Drug 6604_UP Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ARID1A,ADGRF5,AMPH,GAS7,APLP1,PTCH2,BRINP2,ATP2B2,ADAM23,RGS9,BTRC,KALRN,ARHGEF2,CDH10,NRXN3,RCHY1,IFFO1,SUSD5,VCAN,SPOCK2,ST3GAL6,GATM,GUCY1A2,MGAT3,NCAM1,NNAT,OGG1,CAMKV,RETREG1,PPARA,MAPK10,PROX1,PTPRN2,FAM120C,KCTD17,FRMPD1,SLC1A7,SNCA,KIF21B,SPTAN1,COBL,HIF3A,CABIN1,ZIC3" Drug 4569_DN Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "CDC42BPA,CDC14B,CDK13,MARK4,ADGRB2,CACNB2,MAP7,SCARB1,CHM,PLAA,TPP1,CSF1R,SGSM2,ATN1,FEM1B,MRNIP,SPEG,ETV1,EZH1,DLC1,GLYR1,GPM6B,TJAP1,SCIN,ITPKA,MDFI,LYRM9,CNOT4,NPR2,PROX1,SAMD9,PEX5,GAL3ST4,ZNF334,ZNF415,SPTAN1,ELOVL4,VAMP1,ASTN2,DOCK9,PLPPR2,VIPR2,XRCC4,SMIM8" Drug 7016_DN Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "CDC42BPA,EP400,APC,BCAS1,PPFIA3,ARRB2,MPDZ,ARHGEF7,MTMR2,C5,SPAG9,LHX2,RAB28,STOML1,SOCS5,DCAF8,KIAA0586,DCTN1,DLG3,DPH1,DSCAM,IRAK4,EML1,VPS26C,EFEMP1,SRCAP,ZNF276,COPS8,DHX35,MITF,NRGN,NUMA1,PDE3B,SMIM7,STRN3,ZCWPW1,SEC61A2,TRAPPC13,ZFP30,ANKRD6,EMC1,CDK19,ARHGEF9,CABIN1" Drug 7428_UP Enalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,ALCAM,DOC2A,MARCH3,EIF4G3,ATP2B1,MPDZ,CDK5R1,ST3GAL5,MTMR2,CACNA1I,KRIT1,LRRFIP1,RAB28,NIPBL,ENTPD4,FEZ1,SOCS5,DZIP3,CTNND2,C2CD2L,TMCC2,DMPK,DSCAM,DTNA,MRNIP,F8,MALT1,COPS8,POLL,RNFT2,MBD1,SETD4,ZSCAN32,RIPOR1,SNCA,WDTC1,SPART,STX1A,ANKRD12,EHBP1,HEY1,TRIO,UBE3B" Drug 3778_UP Indapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ARRB1,ASTN1,KIF1A,KALRN,CD86,DLGAP1,GPR37L1,TPP1,VAX2,AKAP6,RIMS2,DRP2,ST8SIA3,FRY,ING4,MTSS1L,EXTL1,F5,ATP8A1,FGF12,ERAP1,MSTN,GLS,GNAL,ADAMTS6,MMP16,MYL3,NEFM,NF1,NNAT,PLP1,PLXNB1,EMID1,CNKSR2,SLC1A6,PKNOX2,SLC11A1,ATP10B,MCF2L,FAM189A1,TLL2,TUBB1,PRDM2,CAMK1G" Drug 3865_UP Vincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADORA3,SYT13,APBA2,GAS7,APLP1,BAIAP3,CRLF1,FADS2,SULT4A1,CNTN1,CSF1R,CTIF,TMCC2,C3orf18,F5,KIAA1109,C1orf61,AGAP2,FAM49B,KHDRBS3,IRAK3,KCNJ5,KCNMA1,LIFR,VWA5A,CLDN11,PDE1C,TMOD2,CDK14,MAPK10,PTCH1,PTPRO,FRMPD1,SLN,RBM34,SPTB,NCDN,ROBO3,SMG6,DOCK9,PIK3R5,TPM2,TRPM2,FLRT2" Drug 6464_UP Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACTN2,ADRA1B,LTBP4,SEMA7A,APAF1,APBA2,KCNAB2,SLC4A4,CACNA2D1,NRXN3,ZFYVE9,CSF1,TENM4,SDC3,DCAF4,DMD,DTNA,DYRK1A,HIPK3,EFNA2,EGFR,EGR3,EIF4G2,MTSS1L,GRIN1,HLF,DHX35,JAK2,KCNMA1,LMO1,MATN3,MEF2C,MN1,ADAM22,MYCN,PALM,SEPT4,PPARA,PTHLH,STUM,COA1,SNCA,CLSTN2,NT5M" Drug 7331_UP Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "NDRG3,NDRG2,AMPD3,BIN1,CDK10,KIF1A,CACNA1I,BTRC,ARHGEF2,GPR37L1,ADGRG1,CLU,AKAP7,HAPLN1,PDE4DIP,CNTNAP2,ARHGEF4,RABGAP1L,RCAN1,ST8SIA3,EDNRB,AASS,FGFR1,TRMO,TM6SF1,NF1,PLCD1,PPP5C,PRODH,GON4L,GTDC1,SH3BP2,SLA,SMTN,LIMS2,SLC6A8,ATP10B,CLASP2,SIN3B,ZEB1,TMOD1,CDK20,PLPPR2,SSPN" Drug 3426_DN Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,EPB41L5,ALDH4A1,EIF4G3,BCL2L2,SYNJ2,MAGI1,CSNK1E,PDE4DIP,GPRASP1,GIT2,DBN1,DNM1,DTNA,TNK2,DENND4A,SRCAP,ZNF276,CNTRL,SLC2A6,HSD17B1,MAP4,NUCB1,SETD4,ODF2,SLC25A23,PMS2,ELOVL2,RAD51D,ATG16L1,GTDC1,RNASEL,MYH14,CCDC25,EPN2,ZBTB43,THSD1,ELOVL4,TACC1,TPM1,HIRA,ZNF189,EVI5,PHTF2" Drug 6302_DN Chlorhexidine [55-56-1]; Down 200; 8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "APOC1,ADAM15,CFLAR,C5,KYAT1,QKI,CREM,VCAN,GPRASP1,SMG7,PLPPR4,SLC12A6,DCTN4,ANKMY1,PDLIM5,GART,MSL3,GNAS,GPM6B,GPR37,MAP4K5,SHISAL1,DIPK1A,ZNF862,SLC11A2,NUMA1,PCDH9,MINDY2,PRPH,FUZ,ANKRD6,SHANK2,KBTBD4,TMCC1,WDTC1,ZBTB43,EXOC7,TNS2,WIPF1,KLC2,XRCC4,PRDM2,URM1,SMIM8" Drug 7516_DN Ald1.1-H_000455; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "BEGAIN,SEMA4G,MTMR2,CFAP410,SCARB1,EPS15L1,ENTPD4,FEZ1,SOCS5,DBT,SMG7,DMPK,DTNA,EFNA3,CDKL3,OGA,GART,ARFIP1,NR3C1,KCNJ3,KIF5C,NF1,PFKFB2,RETREG1,PLCD1,RAB3A,RGS12,ROM1,WLS,DOP1A,EMC1,CEP68,PHLDB1,IQCE,TCF7L2,PSD3,ZMAT3,TK2,TPD52,TRIO,TRPC1,RPRM,NSD2,HPS4" Drug 5995_DN Epirizole [18694-40-1]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AMH,AMT,FAM131A,ARHGAP33,QKI,AKAP7,CSF1R,GREB1,ZNF337,MFAP3L,DNM1,DSCAM,PHF20L1,FHL1,CGREF1,GAD1,DISC1,MSL3,GRB10,KIF5C,IPO5,NF1,NUMA1,OXTR,PEX5,RAB3IL1,ATG16L1,ZCWPW1,SEC61A2,ROM1,SBF1,SH3BP2,FERMT1,ZNF365,FCHO1,MAPK8IP3,MCF2L,ARHGEF12,PCDHA6,TK2,TPM1,CDK20,PLPPR2,TFIP11" Drug 3419_UP Spiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "RALGAPA1,SPARCL1,LTBP4,APBA2,APBB2,ASPH,LDLRAD4,USP2,PLAA,NMT2,CRY2,HINFP,CSF1R,FAM169A,DZIP3,DCAF4,DCAF8,DBT,DPH1,C3orf18,FGFR1,FHL1,GPR153,INPP1,ITPKB,LSS,KITLG,NEUROD1,PTPRO,RAB3A,SLC1A7,ELMO2,SPART,ASTN2,IQCE,WSCD1,ZNF34,TK2,MICAL1,ZBTB38,GDPD5,MVB12B,EPM2A,SMIM8" Drug 5476_DN Torsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "MRTFA,APC,CFLAR,CAMK2G,KYAT1,MAGI1,SRSF11,EPS15L1,RAB26,HOMER3,ARMC8,PDE4DIP,DAPK3,RABGAP1L,TRAPPC9,DSCAM,RCAN1,SUGP2,EGFR,PLEKHO1,ANKMY1,MPP6,GAD1,ZMYND11,ZNF276,GNG4,RNFT2,INPP5B,MIA2,NKAIN1,BSDC1,MYH14,WLS,IFT122,LIMCH1,ZBTB43,STX1A,TACC1,WDR7,ARHGEF12,KCTD2,TRIO,PLPPR2,HPS4" Drug 2062_DN Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,AK2,AMT,OGT,PPFIA1,APP,MPDZ,CFLAR,SLC4A7,CSNK1E,USP6NL,SNPH,C2CD2L,SGSM2,SCML2,GART,SRCAP,TXNL4A,PCLO,MAN2A2,MAP4,MITF,ZNF862,NFYA,SETD4,ODF2,NLE1,PLCD1,POLG,RAP1GAP,SBF1,SH3BP2,ZKSCAN3,TTBK2,VAMP1,ARHGEF9,CLASP1,UBTF,LMF1,KLC2,ZBTB14,PRDM2,SMIM8,PHTF2" Drug 7197_UP Isoniazid [54-85-3]; Up 200; 29.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "SEMA6A,CDC14B,PDE8B,ATM,MTMR3,SCARB1,QKI,CYBB,DAPK3,DBT,DSCAM,RCAN1,EGFR,MBNL2,COQ7,EXTL1,KIAA1109,SEMA4D,TXNL4A,GLYR1,CACFD1,NR3C1,AGFG1,KCNMA1,LIG4,PCDH9,SERPINE2,RETREG2,RGS3,MYH14,GSTCD,WLS,FERMT1,BCAN,NUBPL,PPP4R3A,RCOR3,EMC1,CLASP2,MAPK8IP3,TMOD1,TMPO,TPM1,MPPE1" Drug 1853_DN Diprophylline [479-18-5]; Down 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,ANK2,APBB2,APP,BCL7A,SYNJ2,KRIT1,SOCS6,SLC4A7,OSBPL3,DTNA,SUGP2,FCGRT,SRCAP,TXNL4A,PADI2,MAN1B1,ATXN2L,JAK2,MAP4,MDM4,MIA2,ZNF862,NINJ2,SETD4,P2RX7,SERPINE2,PLCB2,POLG,PPP3CC,PTAFR,RET,FERMT1,AMBRA1,ZKSCAN3,SPTAN1,MAPK8IP3,FAM168A,VAMP1,THRA,ZNF32,GDPD5,HPS4,PHTF2" Drug 594_UP arachidonyl trifluoromethyl ketone; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "SYT13,APC,ARNTL,ATP6V0A1,KYAT1,CBFA2T2,SLC24A2,APPL1,ABI1,EFNB3,APH1A,MBNL2,RGS17,PDLIM5,ATP2C1,NCKAP1,NEU3,GNAS,GPER1,GRIA4,BTN2A1,ATXN2L,HMGB1,ICA1,ITIH2,MBNL1,GIT1,MYT1,NACA,NPY,CAMKV,MBOAT7,MAPK10,FAM184A,PAQR6,SLC20A2,CDK5RAP2,SMARCD3,SPART,TEX15,DAAM2,ZMYND8,TMPRSS5,ACTR3B" Drug 3998_UP Etifenin [63245-28-3]; Up 200; 12.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "DDO,ADGRB1,KSR1,CACNA1G,CD86,CDC42,GPR37L1,TPP1,TOX,RIMS3,SPOCK2,SGSM2,DMD,HIPK3,SIDT2,GAD2,GAP43,SIGLEC8,ADAM28,GPER1,GRIN1,CACFD1,KCNF1,KIT,SMAD9,MARK1,ADAM22,NCAM1,C19orf57,PTH1R,CCDC40,GAL3ST4,SBF1,FUZ,KANSL3,SLC6A8,ZHX3,INKA2,CRTC1,TMOD1,CDK20,TRO,TRPC1,DPF3" Drug 4195_UP Lumicolchicine gamma [6901-14-0]; Up 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "BIN1,APAF1,APC,ATP6V0A1,SCAPER,BTRC,SCARB1,RAB26,HOMER3,IFFO1,CRY2,CSF1,SNX29,HIPK3,FAM13A,IRAK4,PLEKHO1,CEND1,PDLIM5,GABRA2,GAP43,GNAO1,GPR17,CACFD1,VWA5A,MMP16,MX1,NF1,PPP2R2B,LRRN3,MAPK8,CNNM2,PTCH1,RPS20,ASAP3,TNIK,ACSBG1,ARC,ATP11A,ADGRL3,TRO,ZMYND8,NSD2,PARP6" Drug 2085_DN Tranexamic acid [1197-18-8]; Down 200; 25.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,ADCY6,KCNAB2,APBB2,APP,RCBTB2,KIAA1549L,CSNK1E,SDC3,SPATA2,RUSC2,PARD6A,DYNC1I1,EDN1,EIF5,SPEG,F3,SCML2,DENND2A,SYT17,SRCAP,ZNF276,COPS8,GNAS,PRRC2B,KLF12,MAP4,MPP2,CNNM2,SYTL2,RGS10,DCUN1D2,SLC1A3,SCMH1,MAPK8IP3,SUPT5H,VPS13A,NSD1,METTL3,HIRA,FAM155A,UBTF,CIAPIN1,EPM2A" Drug 6176_DN chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABAT,NDRG2,BRAP,ADORA2A,AMT,FAM131A,APP,SEMA4G,ARRB1,TAOK2,C2CD2,SH2B1,PPP1R16B,CTNND1,RCAN1,DTNA,SIDT2,TUBD1,COQ7,FOXG1,GALC,SEPT9,AHDC1,POLL,IL11RA,VWA5A,MAP4,NDUFA5,ST8SIA5,PLEC,PTPA,PTK2,ZSCAN32,RXRA,TMEM156,ZNF821,GALNT10,TMCC1,WDTC1,ZCCHC24,KDM4C,KAZN,PSD3,KAT6B" Drug 6001_DN Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "NDRG3,CDC42BPA,STX16,ADAM23,CACNA1I,BTRC,ARHGAP33,B4GALT6,FADS2,QKI,HOMER3,AKAP7,SH2B1,CDON,DTNA,ACSL4,ZNF589,FGFR1,GAD1,DISC1,TDRKH,GRM1,IL6ST,IPO5,MAP4,NF1,CNOT4,CCSER2,TMEM104,RGS3,ASAP3,FAM214B,CXXC4,KDM4B,SPTAN1,IQSEC2,CAMTA2,ITPRID2,MAPK8IP3,PHLDB1,ASTN2,IQCE,TBL1X,ZKSCAN5" Drug 5881_UP Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADCY6,BIN1,CDK10,CDK13,ATP1A3,CAMK2B,CHRNA4,RAB26,HDAC9,SPOCK2,MFAP3L,DSCAM,TOM1,EDN1,HSD17B14,TUBD1,FAM198B,ATP8A1,IQCG,DCTN2,TMEM8B,GLUL,GRK4,GRM7,PADI2,KCND3,KIF5A,VWA5A,MGAT3,AFDN,PILRA,ZSCAN2,ZCWPW1,RGS12,SELL,SLC1A7,PKNOX2,SPP1,SYT1,SMG6,BEX4,TRIO,WNK1,NT5M" Drug 4812_UP Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "APAF1,APBA2,APC,MARK4,CACNB2,HOMER3,PICK1,IFFO1,ENTPD4,NCOR2,ARMCX2,RCAN1,DTNA,CEND1,SORBS1,GAD1,HPGDS,GNAL,GNAS,GRB10,TJAP1,NF1,PCBP3,PCDH9,MINDY2,PRKAR1B,CCDC25,FBXW7,TCP11L1,EMID1,KANSL3,KIF13A,IZUMO4,EMC1,TROVE2,MAPK8IP3,PHLDB1,TNS1,CDK20,CHST5,TRIO,ZIC3,SLC30A3,WNK1" Drug 23_DN 2-propylpentanoic acid; Down 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADORA3,AMPD3,ANK3,CANX,CBLN1,TBC1D5,DBT,TSPAN5,PLEKHA1,COQ7,FGF1,FGR,FHL1,GFER,RUNDC3A,GLS,GRIN1,PTPRT,HMGB1,SCIN,MMP16,MYO7A,NTRK3,NUMA1,OGDH,C1orf54,RXRG,STUM,SCAF8,SLA,SON,SS18,GANAB,VPS13A,TAL1,PCDHGA1,TNS1,CHST5,UBTF,SF1,ZBTB16,PRDM10,SLC17A7,LAS1L" Drug 5526_DN Prednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "RBM10,SLC12A5,PPFIA3,BMP7,CDK5R1,MTMR2,FEZ1,FAM169A,FEM1B,CELSR3,EGFR,MRNIP,FECH,FHL1,BTN2A1,SLC2A6,PADI2,ITPKB,KCNJ3,MAPT,MIA2,OGG1,PCDH9,PRKAR1B,MAPK8,RNASEL,NUBPL,SHANK2,BTBD7,CDK5RAP2,RCOR3,TROVE2,TACC1,EXOC7,TCF7L2,TRIM2,NSD1,CHST8,TGFBR3,VAV1,XRCC4,TFIP11,EVI5,RNF170" Drug 3311_DN Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ALAD,ASPH,SYNJ2,GYG2,BTRC,CA4,ARHGEF2,HOMER3,CRY2,ABCG1,LRIG1,SIPA1L1,FAM169A,CTNND2,EDRF1,DBN1,RCAN1,GPR153,INPP5B,ITPKB,TM6SF1,SLC25A23,SIDT1,PTCH1,RGS10,ROM1,TCP11L1,RPS6KA2,PREX2,RAB3GAP1,SLC15A2,BTBD7,SMARCC2,ZCCHC24,EMC1,TROVE2,FAM168A,PLCB1,TCF7L2,RBFOX2,TRIO,CADM1,VGF,REEP1" Drug 640_UP paclitaxel; Up 200; 0.1uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADD2,AQP6,ASCL1,EIF4G3,MTMR2,CACNA1I,INA,CHRM4,LY86,CLIP3,FEZ2,ATN1,DSCAM,EFNA3,EFNB3,HSD17B14,TUBB4A,GPR153,LILRA2,GRIN1,NXPH3,ARHGAP19,HMX1,ICA1,MMP16,LYRM9,FXYD6,NPY,OPCML,PAK3,PCDH9,PLCD1,PPP2R2B,RGS3,GSTCD,FOXRED2,SPTB,COLGALT2,TCF7L2,LAT2,WNK1,PRDM2,SLC17A7,CAMK1G" Drug 5015_UP Benzbromarone [3562-84-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "SLC4A4,ADAM23,CFLAR,SCAPER,GYG2,ASIC3,CRY2,CSF1,RUSC2,EDNRA,CDKL3,SCARA3,OGA,GAD1,ALDH1L1,POLL,GPM6A,SPACA9,BTN2A1,IRF8,ITPKB,KCNN1,KCNQ3,NF1,SLCO1C1,NTRK3,P2RY1,MTRF1L,CDIP1,LRRN3,MAPK7,ELOVL2,RAD51D,RGS10,NEK11,CXXC4,MAPKBP1,HECW1,ACSBG1,DOCK9,LMF1,NT5M,SEMA3B,TIGD6" Drug 2657_DN Arecoline hydrobromide [300-08-3]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACTN1,BIN1,CDC42BPA,APC,BCAS1,PPFIA3,SYNJ2,KYAT1,REPS2,VAX2,QKI,SDC3,DCAF8,EFNA3,ING4,CDKL3,VPS26C,FGFR1,BAIAP2,AGAP2,POLL,GRIK5,HSD17B1,IL6ST,IPO5,LIG4,MAP4,NPR2,SLC25A23,RAB3IL1,RAD51D,ARHGEF10L,RNASEL,EMID1,WLS,BTBD7,SNCA,ASTN2,KIAA0930,TRIM2,XRCC4,PRDM2,HPS4,MPPE1" Drug 6544_DN 5155877; Down 200; 10uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "NME5,ALAD,PLEKHB1,ABI3BP,DAPK3,GIT2,LYPD1,SMG7,PLEKHA1,VPS26C,TESK2,TRMO,DENND2A,GAD1,ALDH1L1,GLI2,INPP5B,MN1,MT1M,NFYA,SLC11A2,PALM,KCTD15,SPATA6,PTPRN2,RAD52,RALGDS,KIRREL1,PAQR6,SCN8A,BTBD7,EMC1,CAND2,BEX1,SPTAN1,DDN,NXT2,COBL,SYNE1,RUNDC3B,ZKSCAN5,VGF,LAT2,ST7" Drug 3681_DN Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABR,ARID1A,MRTFA,BIN1,APC,CDK13,HAP1,CACNA2D2,NRXN3,CNTFR,PDE4DIP,SLITRK5,PPP6R2,CTIF,SMG7,CDON,E2F5,STX2,OGA,FYN,GLRB,GPR37,SYNPO,TAGLN3,MX1,ODF2,EPN1,PSMD13,PTN,RAB3IL1,ENOX1,MCMBP,SBF1,SCN8A,WDTC1,SPTB,MAPK8IP3,ARC,PSD3,AHCYL2,CHST8,LAT2,NSD2,WNT7A" Drug 5398_DN Azacyclonol [115-46-8]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "APP,BRINP2,ALDH7A1,BTRC,ADGRG1,SLIT2,RAB28,HOMER3,EDRF1,GPRASP1,TBC1D5,MFAP3L,LYPD1,VPS26C,F3,ACSL4,ZNF589,FGFR1,RUNDC3A,KCNMB4,SPACA9,ELOVL5,MATK,NF1,CNOT4,NUMA1,FSD1,RAB3IL1,RAD52,RNASEL,GSTCD,SH3BP2,SLC1A7,RBM34,EMC1,CEP68,ARHGEF9,PLCB1,ATP11A,MCF2L,EXOC7,TCF7,TPM1,ZNF74" Drug 6878_DN "H-89, Dihydrochloride; Down 200; 0.5uM; MCF7; HT_HG-U133A" Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "SERPINA3,ASIC1,SEMA6A,AMT,APBB2,ARNTL,PDE8B,MARK4,CAPRIN2,MTMR9,CDK5R1,MTMR2,CACNA1D,SRSF11,FEZ1,ARHGEF4,RIMS2,SLC12A6,LRRC23,GPR153,ERAP1,ALDH1L1,SRCAP,GPER1,ADAMTS13,MITF,NF1,PDE3B,PLCD1,POLG,MAPK7,RGS12,NEK11,BTBD7,EMC1,SPTAN1,CEP68,PHLDB1,SMG6,TRIM2,TGFBR3,TMOD1,CDK20,PLPPR2" Drug 1955_UP Haloperidol [52-86-8]; Up 200; 10.6uM; PC3; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACLY,BRAP,STX16,ADAM15,SLC25A14,MAP7,FADS2,MAP4K4,KLHL3,SMG7,G3BP2,DRP2,EFNA3,C3orf18,FGF1,CELF1,DENND2A,GBX2,RNFT2,RASSF8,KCNK1,KCNN1,CCSER2,PLTP,BCAS3,TMEM104,RIPOR1,RGS3,CCDC25,ATXN2,SEC14L1,ZNF821,ZNF365,ZSWIM8,IQSEC2,EXOC7,WSCD1,HEY1,KCTD2,TNS1,TSC2,UBTF,PLPPR2,GDPD5" Drug 1145_DN "aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,NCOA1,SLC4A4,SCAPER,ZFYVE9,SEC31B,EDRF1,MED24,SEMA4D,OGA,TRAF3IP2,DISC1,GLS,LPAR4,ARHGAP12,OCRL,PIK3R1,PLCB2,PLTP,PTPA,TMEM104,RET,GTDC1,FBXW7,DGLUCY,ATXN7,SEC14L1,CLSTN1,RAB3GAP1,ARFGAP1,SMARCC2,WDTC1,ZCCHC24,SPTAN1,TSPYL2,SS18,NCDN,EXOC7,TCF7L2,CABIN1,GORASP1,URM1,UBE3B,AAAS" Drug 915_UP topiramate; Up 200; 3uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "APAF1,APBB2,APC,PPFIA3,GYG2,SRSF11,SH2B1,PPP6R2,CTIF,GIT2,DBT,SMG7,AASS,RGS17,CDKL3,RACK1,GNG4,PRUNE2,CNTRL,RNFT2,INPP5B,KCNH2,MAP4,NCAM2,FA2H,MINDY2,PPP5C,GON4L,PLPPR1,RGS12,RNASEL,TRAPPC13,URGCP,EPN2,ZCCHC24,POGZ,THSD1,TTBK2,JMJD6,AHCYL2,ZMYND8,VLDLR,WNK1,ITM2C" Drug 3027_UP Dichlorphenamide [120-97-8]; Up 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ANK2,SLC4A4,MTMR7,LARGE1,COL9A3,ARHGEF10,CHD5,PDE4DIP,BRINP1,MFAP3L,TMCC2,DRD1,AASS,RASGRP2,CORO2B,GABRA3,SIGLEC8,ADAM28,GNAS,STON1,GRM1,HPSE2,SCIN,KIT,MYT1,NEUROD1,NOVA2,NTRK3,CCDC40,KLHDC8A,NLGN1,SLC8A2,SLC11A1,SLCO1A2,PEG10,DDN,TACR1,TCF7L2,AP4E1,TIAM1,TK2,RIMBP2,FLRT1,ZNF711" Drug 3621_DN Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,PLA2G6,ARHGDIG,PLA2G4C,ASPH,SLC4A4,HAP1,CAMK2B,NEURL1,VAX2,CNTNAP2,ATN1,HIPK3,FOXG1,SEMA4D,GAB1,TDRKH,SPACA9,HSD17B1,KCNJ5,KPNA5,MDM4,OXTR,PFKFB2,EPN1,ZSCAN2,RPS6KA2,SEC14L1,PPP1R9A,CXXC4,SMARCD3,SOX2,ZCCHC24,DOK5,EMC1,KDM4C,ZC3H13,INKA2,PLCB1,BHLHB9,FLRT2,VGF,WIPF1,EMSY" Drug 6552_UP prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AK2,PLA2G6,GAS7,CDK10,RIPK1,SCAPER,ARHGEF1,CDH18,CLGN,AKAP7,LRIG1,MFAP3L,EDNRA,EFNA3,ENO2,DMTN,VPS26C,EFEMP1,NR3C1,SLC2A6,MAP4,MOBP,MSR1,NUMA1,PCDH9,SMIM7,PLXNB1,PPP5C,CNNM2,RPS6KA2,FERMT1,SLC20A2,ZCCHC24,TROVE2,TTBK2,TACC1,KAZN,SEMA4A,IQCE,TNS2,BEX4,LMF1,LAT2,SMIM8" Drug 6447_UP Metyrapone [54-36-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "BIN1,APBB2,GAS7,SEMA4G,ATP1A2,SCAPER,SGCE,BAIAP3,WHRN,CNTNAP2,RIMS2,EDRF1,RIMS3,CTIF,RUSC2,EDNRB,ST3GAL6,PDLIM5,GAD2,SIGLEC8,RAB40B,CACFD1,ITIH2,ADAM22,OPCML,PDE3B,CAMKV,PPARA,PPP5C,PTAFR,BSDC1,EMID1,SLC1A7,KIF21B,UNC5B,ZC3H13,ARHGEF9,POPDC3,HEY2,R3HDM1,WIPF1,EMSY,NT5M,PHTF2" Drug 4215_DN Zalcitabine [7481-89-2]; Down 200; 19uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADCY6,MTUS1,BIN1,BCL2L2,OSGIN2,CLU,ABI3BP,SLITRK5,ARHGEF4,PPP6R2,RUBCN,USP6NL,COQ7,DENND4A,RRAGB,F8,TRMO,PDLIM5,FYN,NR3C1,AGFG1,SHISAL1,DIPK1A,JAK2,MAPT,NDP,CCSER2,RC3H2,PTCH1,ZSCAN32,PTPRE,TMEM231,FAT4,SEC61A2,ANKRD6,TNIK,ZBTB43,IQCE,TRIM2,ZNF34,TRPC1,XRCC4,HPS4,MPPE1" Drug 6452_DN Tyloxapol [25301-02-4]; Down 200; 4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,SEMA6A,AMH,PPFIA1,CDK10,PLA2G4C,MTMR2,GYG2,BTRC,PDE4DIP,TOM1,EFNB3,SUGP2,PLEKHO1,GAD1,MALT1,BTN2A1,RASSF8,KLC1,IPO5,THYN1,PDE3B,PDE4A,PMS2,PRPH,NDUFS7,ELOVL2,TMEM231,KHDRBS2,RGS3,RGS10,SMTN,CXXC4,KDM4C,TROVE2,EXOC7,CABIN1,TPM1,PLPPR2,VGF,XRCC4,SYNC,SEMA3B,KAT6A" Drug 6463_DN Fluspirilen [1841-19-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADD3,ALAD,APBB2,APP,LDLRAD4,CNOT8,LHX2,BAG4,ENTPD4,AKAP12,ABCG1,GIT2,DBT,DNM1,EFNB3,ENO2,STX2,FHL1,DPYSL4,USP21,GPR153,MSL3,HNMT,JAK2,VWA5A,LYRM9,NEK1,SSH1,RETREG1,RAD51D,ITSN1,ZKSCAN3,CXXC4,EMC1,UNC5B,ATP11A,KIAA0930,RBFOX2,SYNC,LRP8,EPM2A,SMIM8,ACTR3B,SSPN" Drug 6792_UP Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "DPF1,PLA2G6,KCNAB2,CDC14B,ALDH4A1,ATP2B2,RGS11,GYG2,BAIAP3,CFAP410,CACNB2,NEURL1,CDC42,STOML1,TMCC2,EDNRB,CEND1,FHL1,HPCAL4,GLYR1,ICA1,TJAP1,KIT,MOBP,PDE1C,PPARA,ACSM5,TCP11L1,RYR1,PEX26,FAM214B,CCDC88A,SOX2,ACSBG1,SYT11,PLCB1,WSCD1,THRA,PIK3R5,UBE3A,CLIP2,NT5M,EPM2A,SENP7" Drug 487_UP WY-14643; Up 200; 100uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,NDRG2,ANK1,PPFIA3,ASCL1,CADM3,CACNA1I,MYRF,CAMK2B,SLC25A14,CDH10,DAPK1,DRP2,PIPOX,ZMYND10,ZNF589,FLNC,SMC2,ATP8A2,LILRA2,GRIK5,GRIN2C,GRM2,FAM107A,KCNB1,MAPT,MBP,MOBP,PIK3CD,PACSIN1,MAPK8,GAL3ST4,RNASEL,TCP11L1,DZIP1,PKNOX2,SMARCC2,CDK5RAP2,CAMSAP2,WSCD1,KIAA0930,BHLHB9,TMPRSS5,STMN4" Drug 453_DN "indomethacin, USP; Down 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABAT,C1QTNF1,ALAD,APOC1,ASPH,CBFA2T2,CNOT8,ENTPD4,SOCS5,SDC3,PUM1,GPRASP1,LYPD1,DLG3,DYNC1I1,DSCAM,DTNA,ECM2,SORBS3,BSCL2,TUBD1,VPS26C,NSG1,GPR37,BTN2A1,ATXN2L,LAMP2,NELL2,OMG,OPCML,OPRL1,SMOX,STUM,FNDC3A,ZNF430,KBTBD4,CDK5RAP2,TSNAXIP1,KIAA0930,SEZ6L,TMPRSS5,ZKSCAN5,GDPD5,NAV2" Drug 7482_DN Acetohexamide [968-81-0]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "CDC42BPA,BACH1,CFLAR,SYNJ2,MTMR2,B4GALT6,FAM189A2,QKI,AKAP7,SLC4A7,RNF14,FEZ1,GPRASP1,GIT2,HP1BP3,DNM1,MED12,GNE,MAMLD1,SORBS3,COQ7,GPD2,GRB10,NR3C1,JAK2,KIF5C,LIG4,NF1,NFYA,FSD1,MED1,PTPRE,FAM184A,RGS10,FNDC3A,ABLIM3,PPP4R3A,SMTN,BTBD7,ZBTB43,ARHGEF9,AHCYL2,ZNF24,TFIP11" Drug 7508_UP CP-863187 [668981-07-5]; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "DPF1,ABR,APC,APLP1,ARHGDIG,MTMR2,C5,BTRC,CA12,SCARB1,AP4M1,ABCG1,SOCS5,MED12,DNM2,DTNA,F3,GRB10,SPACA9,ELOVL5,DIPK1A,MAP4,AFF1,NUMA1,SETD4,PDE3B,PDE4A,SLC25A23,MBOAT7,TMEM231,RAB3IL1,CEP97,RALGDS,RAP1GDS1,ZNF821,ASAP3,SHANK2,SEMA4A,SMG6,CRTC1,TPD52,ZKSCAN5,WIPF2,SSPN" Drug 2752_UP Thiorphan [76721-89-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "CDC42BPA,BAIAP3,LHX2,FADS2,DOCK4,DBT,TMCC2,KBTBD11,HS3ST2,DNAH9,DTNB,SNX29,PLXNC1,EIF4G2,LRRC23,FER,TPK1,B3GAT1,GAB1,GNG3,ADAMTS13,GRM1,IL6ST,KCNB1,KCNMA1,AFDN,ADAM22,NTRK2,PALM,PLTP,MTRF1L,MAPK8,PTN,PTPRN2,RGS12,KCNIP1,PEX26,WDTC1,MAPK8IP3,SYN2,WSCD1,TK2,KAT6A,ADAMTSL3" Drug 2668_DN "estradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A" Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "RALGAPA1,KIDINS220,BCAR3,MRTFA,TRMT9B,AMT,ANK3,CACNA1G,IQCK,SGSM2,TRAPPC9,CDON,ING4,MRNIP,ELN,PIPOX,ZNF44,SEPT9,GATM,RUNDC3A,GRM8,MAP4K5,ATXN2L,TJAP1,KCNMA1,MAPT,MID1,MYO6,SERPINE2,WDR25,KHDRBS2,SCN2B,GALNT10,CCDC92,ANKRD6,EPN2,ARHGAP26,OBSL1,TNS2,CDK20,TRIO,ZMYND8,CLIP2,XRCC4" Drug 3313_DN Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,C1QTNF3,ALAD,LTBP4,AMPD3,APOC1,ASPH,NCOA1,GYG2,CACNB2,CACNA2D2,TAOK2,APPL1,GIT2,RCAN1,DTNA,TSPAN5,SORBS3,ING4,ERAP1,DISC1,GCNT2,MALT1,TXNL4A,INPP5B,NPTX1,PTHLH,ZDHHC14,RGS10,TCP11L1,WLS,KIF16B,ZNF365,BTBD7,LIMCH1,SPTAN1,PLCB1,ATP11A,SEMA4A,PDLIM2,PARD3,ZBTB14,EMSY,PRDM2" Drug 2018_UP Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; HL60; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADD2,C1QTNF1,CDC42BPA,RASL11B,MTMR2,VCAN,SLITRK5,INTS1,DAPK1,SPOCK2,DBT,SPATA2,ATN1,EFNA3,MRNIP,DMTN,POMT1,ATP2C1,FYB1,HBS1L,SRCAP,PCSK1N,MCHR1,CACFD1,HNMT,MPP2,NEFH,PLEC,PMS2,PPP2R2B,ARID4A,RGS12,UEVLD,RPS6KA2,ATXN7,FAM102A,MAPKBP1,SRPK2,FCHO1,TK2,TSC2,TFIP11,NT5M,NLRP3" Drug 6336_DN Propafenone hydrochloride [34183-22-7]; Down 200; 10.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACTN1,APLP1,ATP2B1,MTMR9,CNOT8,SDC3,ARHGAP32,C2CD2L,SMG7,SGSM2,DLG3,FER,FGFR1,BAIAP2,TRAF3IP2,TMEM8B,DISC1,CRCP,GPER1,NUDT21,GUCY1A1,MAP4K5,N6AMT1,SLC11A2,OGDH,CLDN11,NLE1,MAPK3,ELOVL2,PTPRN2,TRAPPC13,FUZ,SLC6A8,ZBTB43,COLGALT2,MAPK8IP3,ARHGEF9,KIAA0930,PLPPR2,XRCC4,TRIM9,FTSJ1,TFIP11,ST7" Drug 5880_DN Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "BRAP,APP,ALDH7A1,KYAT1,ADGRG1,CHN2,KIAA1549L,CSNK1E,VCAN,CNTNAP2,ZNF337,DBT,LYPD1,EFNA3,COQ7,ETV1,FGF13,B4GALNT1,ZNF276,GLYR1,PRRC2B,MBD1,SCAMP5,GIT1,NDP,PBX1,ZNF426,SIDT1,PSMD13,RAB3A,MAPK12,SUPT20H,DOCK10,BTBD7,SMARCA4,GSE1,JMJD6,KAZN,EXOC7,WWC1,IQCE,THRA,PARD3,MAP3K12" Drug 2146_DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "PLA2G6,CDC42BPA,PPP4R4,SYNJ2,FOXN3,PLAA,TMEM184B,IQCK,CSF1R,CSNK1E,PPP1R16B,ZNF337,TRAPPC9,EFNA3,RASGRP2,CDKL3,SEPT9,POLL,PSRC1,KCNJ5,NPR2,NUCB1,P2RY1,PIK3CD,PTPA,TMEM104,RAB3IL1,RAP1GAP,ROGDI,MYH14,CARF,FAM214B,SLC11A1,SNCA,KDM4B,SP4,FCHO1,PLCB1,SLC44A1,TMOD1,TNS1,LMF1,HPS4,ST7" Drug 1178_UP fluphenazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "APBB2,APOC1,APP,ARNTL,NCOA1,MAP7,CRY2,CSNK1E,PDE4DIP,CNTNAP2,KIAA0753,ATN1,EIF4G2,EPB41L2,RASGRP2,ANKMY1,CAMSAP1,ANKFY1,INPP5K,PCDH17,RND1,PTGDR2,IL6R,LSS,MEF2C,MX1,NINJ2,SLC11A2,NTRK2,P2RX7,STRN3,NECAB2,POLG,MINDY2,PTPRN2,KLHL11,SLC11A1,ZBTB43,MAPK8IP3,RGL1,EXOC7,ARHGEF12,TMOD1,PHTF2" Drug 4654_DN Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADCY6,ALDH4A1,MTMR2,CANX,SOCS6,B4GALT6,RAB28,NIPBL,SLC4A8,BAG4,VCAN,DAPK3,BRINP1,FAM13A,ING4,ETV1,SEMA4D,SYT17,DIPK1A,LIG4,PDE4B,PFKFB2,PLCD1,PPARA,PRKAR1B,PTK2,ZSCAN2,KHDRBS2,ROM1,FBXW7,EPN2,KDM4B,ARHGAP26,SPTAN1,TROVE2,CAMTA2,SS18,MAPK8IP3,TK2,TMPO,UBTF,WNK1,WIPF2,PHTF2" Drug 2961_DN (S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "MTUS1,MARK4,SLC4A4,ADAM23,CD38,AP4M1,EPS15L1,RAB28,IQCK,MAGED1,CSF1,PDE4DIP,DZIP3,RUSC2,TUBD1,FHL1,NOP56,CELF1,ERAP1,SRCAP,AHDC1,GPD2,SLC2A6,ICA1,MAP4,MX1,ZNF862,OGG1,PFKFB4,PTPA,TMEM231,ZDHHC14,RGS10,ATXN1,DDN,PJA1,EXOC7,TBL1X,TCF4,ZEB1,CABIN1,FLRT2,PRDM2,NLRP3" Drug 3145_DN Isometheptene mucate; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABHD6,MTUS1,AGT,APOC1,MARK4,CNTN1,IQCK,CREM,ABCG1,DGKG,SPOCK2,ERCC2,ETV1,DLC1,CAMSAP1,AGAP2,ZNF44,GOLGB1,IL6ST,KCNJ5,NOS1,CNOT4,OGG1,PFKFB4,PLCD1,SYTL2,ZFHX4,ST6GAL1,TNIK,TSNAXIP1,SP4,ARHGAP26,IQSEC2,ST5,FCHO1,NSFL1C,SYN2,CAMSAP2,TCF7L2,PCDHGA10,SYNE1,THRA,BEST1,MAP3K12" Drug 2703_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "MTUS1,SPARCL1,SRPX,DNAH17,ASPH,ADGRB1,SYNGR3,GPR37L1,NCOR2,DZIP3,CEND1,REEP2,STON1,GRM1,RASSF8,GPR45,KCNC1,KCNF1,KIFC3,PACRG,MYT1,NELL2,NF1,SLCO1C1,NTRK3,ENPP2,PROX1,KHDRBS2,RGS12,SUGCT,CCDC102B,SCN7A,SNAP25,PHLDB1,ACSBG1,SYT5,KIAA1107,RPGRIP1L,PHF24,PSD3,THRA,TRPS1,VSNL1,EVI5" Drug 2002_UP Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACLY,ACTN2,AMT,PPFIA1,APBB2,NRP2,SCAPER,CAST,CLDN10,KRIT1,SRSF11,RABGAP1L,FKTN,ATP2C1,GAP43,RUNDC3A,CRCP,GRIK5,NXPH3,NAP1L1,NTRK3,PPM1B,PKN2,RAP1GAP,BSDC1,CCDC25,CLIP1,AP1AR,SLC1A7,SLC11A1,SLN,KDM4B,SON,FNBP1,ZC3H13,LARP4,MAPK8IP3,VAMP1,SYN2,ANKRD12,AHCYL2,NPDC1,EPM2A,RNF170" Drug 1669_DN haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABHD6,ADCY6,ALAD,PPFIA3,NUMB,BCL2L2,BMP7,WASF1,ENTPD6,ZMYM4,SRSF11,DLG3,ENO2,CDKL3,VPS26C,EFEMP1,KIAA1109,DIDO1,CACFD1,RNFT2,ITPKB,IPO5,MAP4,NAP1L2,NF1,OGDH,PFKFB3,ELOVL2,TMEM231,RNASEL,SH3BGR,PEX26,EPN2,ZKSCAN3,EMC1,TSPYL2,LHPP,TROVE2,MAPK8IP3,ELOVL4,TCF7L2,OBSL1,NR2C2,WIPF2" Drug 576_DN "novobiocin sodium, USP; Down 200; 100uM; MCF7; HG-U133A" Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "OGT,ALDH4A1,HIP1R,KRIT1,ENTPD6,QKI,DAPK3,LYPD1,DNM2,ATN1,SEZ6L2,SEC23B,ARFIP1,PRRC2B,RNFT2,ARHGAP19,STMN1,MBNL1,MYO6,NFYA,SNX10,POLG,FSD1,PTPA,SPDL1,RALGDS,RAP1GDS1,RGS3,FNDC3A,SLC11A1,ZKSCAN3,CDK5RAP2,KDM4B,SON,EMC1,TSPYL2,SRPK2,KAZN,IQCE,ARHGEF12,ACTR6,KAT6B,TRIO,MPPE1" Drug 3129_DN Isradipine [75695-93-1]; Down 200; 10.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "MTUS1,APBB2,ZBTB10,NCOA1,BCL7A,CAMK2G,CLCN4,TPP1,NIPBL,CREM,HDAC9,ZNF337,INTS1,GIT2,DTNA,HIPK3,FRY,CAMSAP1,ATP2C1,TXNL4A,GLYR1,PCLO,VSIG4,AFDN,MX1,ZNF426,PTPA,BSDC1,RGS10,RASA3,CCDC88A,ZCCHC24,SS18,KAZN,PJA1,TCF7L2,THBS4,TMPO,R3HDM1,TPM2,ZNF24,ATP6V0E2,UBE3B,PHTF2" Drug 6358_DN Naproxen [22204-53-1]; Down 200; 17.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP1B1,C1QTNF1,MRTFA,SHROOM2,ARNTL,FOXN3,SMG7,SGSM2,KBTBD11,DSCAM,LPAR6,ELAVL2,TNK2,SCML2,FER,PRELID3A,ZMYND11,GNG4,PRRC2B,TDRKH,KIF5C,MX1,NUCB1,CCSER2,RC3H2,ZSCAN32,SUGCT,ASAP3,URGCP,LIMS2,BEX1,DDN,TCF4,ZKSCAN5,HIRA,LMF1,WNT7A,NDRG4,SH3GLB2,EMSY,SCG2,URM1,PHTF2,RNF146" Drug 4441_DN chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "AP2A2,C1QTNF1,C1QTNF3,AMT,APP,ADAM23,ADGRB2,CFAP410,NRXN3,CLCN4,RAB26,AKAP7,COL9A3,CSF1R,RUSC2,SGK2,SIDT2,CELSR3,PLXNC1,ING4,FGFR1,POMT1,PRELID3A,HBS1L,ICA1,SHISAL1,KITLG,PFKFB4,PLCB2,SLC25A23,TMEM231,TMEM206,FUZ,SNCA,WDTC1,EMC1,SPTAN1,LHPP,SAMSN1,MAPK8IP3,IQCE,ZEB1,GPR161,DPF3" Drug 3093_UP Pipemidic acid [51940-44-4]; Up 200; 13.2uM; HL60; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,BIN1,KCNAB2,CADM3,BMP7,RUNX1T1,REPS2,CDH10,RAB33A,CNTN1,CREM,ABCG1,CSNK1E,SMG7,DLG4,DNM2,EDNRB,EFNA3,RASGRP2,ETV1,DLC1,FGFR1,PRELID3A,GNAL,GNG3,GPM6B,SCIN,ITPKA,KCNJ5,KHK,N6AMT1,MYT1,PFKFB4,POU3F2,FAT4,ZCWPW1,SHANK2,SLC14A1,CXXC4,ZC3H13,TBCEL,PCDHGB6,CHST5,CLIP2" Drug 4550_DN Methimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "CASK,ARRB2,ASPH,BAIAP3,SYNGR3,CDH10,RAB28,NRXN3,AKAP7,AKAP5,CSNK1E,PPP6R2,RIMS3,MFAP3L,EDNRA,FAM13A,EGFR,EIF5,ING4,ANKMY1,BAIAP2,PRELID3A,TRAF3IP2,GRM1,MX1,PALM,CNTLN,PEX5,SUGCT,DCUN1D2,ATXN7,IL17RB,SH3GL2,SLC1A7,SHANK2,SMARCD3,IQSEC2,SYT11,TIAM1,CADM1,RPRM,MICAL1,SPHK2,NAV3" Drug 5230_UP rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC1,NME5,SRPX,AMT,SEMA7A,APBB2,APC,APOC1,ASPH,CACNA1I,CA4,HAP1,INA,CRMP1,FAM169A,SDC3,EFNA3,FHL1,GPR153,GFER,POLL,NR3C1,GRM7,KCNN2,ZNF862,NDUFA5,PLCD1,ASIC4,KIF13A,KDM4C,SPTAN1,KIAA1107,R3HDM1,PARD3,TNS1,VLDLR,KCNK12,HPS4,SLC17A7,ITM2C,EPM2A,KAT6A,TIGD6,GAN" Drug 4842_UP Picrotoxinin [17617-45-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASIC2,GAS7,APP,MARK4,BAIAP3,CFAP410,CLU,COL9A3,ENTPD4,MFAP3L,DTNB,RRAGB,ARMCX1,C1orf61,GAD1,GLYR1,GPM6A,GPER1,PCLO,SLC2A6,ATXN2L,ICA1,DIPK1A,ITIH2,VWA5A,MAOB,SNX10,EPN1,MAPK7,WLS,WDTC1,DDN,SAMSN1,MAPK8IP3,SYT11,PLCB1,PDLIM2,WSCD1,CRTC1,TNS1,TRH,XRCC4,ZNF74,NT5M" Drug 256_UP rofecoxib; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ARID1A,NDRG2,CDK10,ARNTL,CADM3,MPDZ,MTMR2,SLC25A14,CDC42,DLGAP2,SOCS6,ASIC3,CHN2,TMCC2,SNX29,MTSS1L,F5,IQCG,NSG1,GAB1,GLRB,GRIN1,PADI2,MATK,MMP17,ADAM22,NF1,PPP2R2B,PPP2R5C,CEP41,C1orf54,FAM184A,SLN,SON,TNIK,NMNAT2,MAPK8IP3,FAM208A,TNS2,TEX15,TMPRSS5,VIPR2,WIPF1,XRCC4" Drug 1754_UP Tomatidine [77-59-8]; Up 200; 9.6uM; HL60; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACADM,NDRG2,ADCY6,APAF1,SHROOM2,SLC4A4,CADM3,MTMR2,INA,NEURL1,ARHGAP33,RAB26,CNTN1,NCOR1,DOCK4,INTS1,DTNA,SGK2,DMTN,CEND1,PCDH17,RAB30,ITIH2,NELL2,PHKG1,RETREG1,PLCB2,MBOAT7,PTPA,PRPSAP2,ZSCAN32,GTDC1,RNASE1,EXD2,TMEM206,TCP11L1,FNDC3A,SLC11A1,ELMO2,WDTC1,FBXW11,TK2,FLRT2,SLC17A7" Drug 123_UP dexamethasone; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADD2,APP,PDXK,ARSE,CADM3,WASF1,BAIAP3,CFAP410,DNAJB5,DTNA,EFNB3,EGR3,EPB41L2,DMTN,FHL1,AFF2,TRMO,PDLIM5,NSG1,INPP5K,L1CAM,MAP4,ADAM22,NELL2,MAPK8,PTPRN,RALGDS,CRTAC1,RGS3,RIC8B,FOXRED2,ZC3H13,LHPP,LMO3,CEP68,GANAB,KAZN,EHBP1,WSCD1,KCTD2,SEZ6L,TRPM2,SEMA3B,SNX27" Drug 2273_UP Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ACTN2,LTBP4,TRMT9B,PDE8B,MARK4,ADGRG1,TPP1,DNAJB5,CREM,SNCAIP,PLCH2,CTIF,ING4,ELN,KCNMB2,ZNF589,GAD1,GPR37,GRM8,INPP1,SMAD1,MAP4,ADAM11,NF1,NNAT,OMG,PALM,PDE3B,MINDY2,MAPK7,MAPK8,RELN,PTH1R,CCDC40,RAD52,C1orf54,RYR1,PKNOX2,SNCA,EXOC7,UCHL1,UGT8,SLC30A3,MVB12B" Drug 4733_DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "PPFIA3,CFLAR,MTMR2,CA12,ARHGEF2,FOXN3,FAM189A2,ARMC8,SLC4A7,LRIG1,PDE4DIP,DBT,MFAP3L,RABGAP1L,NR1D2,RRAGB,ACSL4,FGFR1,PDLIM5,ZMYND11,GLYR1,GPD2,MAP4K5,IL6ST,INPP5B,MIA2,KITLG,NF1,NFYA,PDE3B,SERPINE2,RETREG1,STRN3,POLG,ZNF821,FNDC3A,FAM214B,LIMCH1,THSD1,NXT2,IQCE,TPM1,CDK20,VAV2" Drug 1121_UP DL-PPMP; Up 200; 2uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ABR,ANK3,APP,ATM,EIF4G3,BACH1,SLC25A14,CARS,CBFA2T2,CREM,USP6NL,RHOBTB1,DNM1,TRAPPC9,RBM12,PCOLCE2,EPB41L2,FGFR3,SEC23B,TRAF3IP2,GLYR1,PCSK1N,GPR19,MAN1B1,KCNJ3,MARK3,NRGN,PC,CCSER2,PPP3CA,VPS13C,CYBC1,PSMD13,C1orf109,PLEKHB2,CCDC25,SMARCC2,TROVE2,KLHL7,IQCE,KCTD2,TRIO,FIP1L1,JMJD1C" Drug 2124_DN Mafenide hydrochloride [138-37-4]; Down 200; 18uM; PC3; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ADGRF5,CDK10,ARRB2,ADAM15,SYNJ2,MTMR2,CANX,BAG4,NCOR1,PPP6R2,GPRASP1,KIAA0753,CDON,EFNA3,ZNF589,ANKFY1,CGREF1,GCNT2,SHISAL1,INPP5B,KCNMA1,MITF,NASP,NFYA,PTPA,RAB3A,RAD51D,ZNF671,RPS6KA2,PAQR6,SUPT20H,SLC1A7,PEX26,TSPYL2,SS18,MAPK8IP3,SYT11,COBL,EXOC7,TCF4,ZEB1,AHCYL2,HIRA,LMF1" Drug 6230_UP Sulfinpyrazone [57-96-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "ASPHD1,ARID1A,AP2A2,TRMT9B,ANK3,ATM,KYAT1,LY86,NCOR2,MFAP3L,APH1A,MBNL2,EGR3,SORBS3,ATP8A1,GLS,GRB10,GRM7,BTN2A1,INPP5B,KHK,KIF2A,MMP16,MSR1,LYRM9,TREM2,PCDH9,PHKG1,SLC25A23,NEK11,RASA3,SYBU,SHANK2,ZC3H13,ZBTB43,CEP68,SATB2,TRIM2,DAAM2,AMACR,GDPD5,SEMA3B,KAT6A,NUP214" Drug 2305_DN Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 9.75E-03 1.00E+00 4.61E-02 5.24E-01 44 198 "MRTFA,CDC42BPA,CDK13,NCOA1,CACNA1D,PTBP2,UBE2L6,HOMER3,EDRF1,KBTBD11,DTNA,TOM1,EFNB3,SORBS3,CINP,FAM49B,GPR153,AHDC1,TXNL4A,NR3C1,MUM1,ATXN2L,KCNN2,VWA5A,ZNF862,CNOT4,SLC25A23,PPP5C,PRKAR1B,ELOVL2,FBXW7,FOXRED2,FAM214B,SHANK2,BTBD7,IQSEC2,TTBK2,PHLDB1,STX1A,MCF2L,EXOC7,UBTF,SEMA3B,SSPN" Drug CID000004816 picrotoxinine Stitch 9.77E-03 1.00E+00 4.61E-02 5.25E-01 18 65 "CLCN3,CLCN4,DBI,GPHN,ZMYND10,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,ATP8A2,GLRB,KCNMA1,PTN" Drug CID000003366 5-fluorocytosine Stitch 9.88E-03 1.00E+00 4.66E-02 5.30E-01 15 51 "MRTFA,UPRT,CDR1,PLEKHB1,DNM1L,TUBB4A,ZMYND10,AGAP3,FOLH1,GART,KCNK2,PDCD2,EPN1,ARID4A,TK2" Drug ctd:D016047 Zalcitabine CTD 9.88E-03 1.00E+00 4.66E-02 5.30E-01 15 51 "SLC4A8,SV2B,ARNT2,ST8SIA3,LUZP2,HTR2A,KIF5A,NPY,NTRK2,ROBO2,FAM81A,NECAB1,SLC35G2,TK2,VGF" Drug CID000014945 oxoiron Stitch 9.88E-03 1.00E+00 4.66E-02 5.30E-01 15 51 "PRC1,CDO1,PNKD,ARHGAP32,CASP8AP2,ENO2,F3,HBS1L,DNER,FEZF2,RDX,SLC11A1,SOX10,TF,WIPF1" Drug CID000001050 pyridoxal Stitch 9.91E-03 1.00E+00 4.68E-02 5.32E-01 32 135 "ABAT,PDXK,MTMR2,NFS1,CBS,KYAT1,P2RX6,ENTPD2,CDO1,SLC22A6,GAL3ST1,CRYM,PLCXD3,CTH,GPHN,F3,FECH,GAD1,GAD2,LOXL3,GPT2,PLCD4,P2RX7,P2RY1,PLCB2,PLCD1,PYGM,SHMT2,ADHFE1,PLCB1,TF,ETNPPL" Drug CID000002471 bumetanide Stitch 1.00E-02 1.00E+00 4.72E-02 5.37E-01 46 209 "SLC12A5,AGT,AQP6,ATP1A1,ATP1A2,ATP1A3,SLC4A4,ATP1B3,BLM,CA4,CA12,SLC5A11,SLC22A6,CLU,SLC4A7,SLC4A8,SLC32A1,DCT,DCTN1,SLC12A6,EDN1,EDNRA,ACTL6B,INPP5K,KCNK3,MTR,NBL1,NPPA,KLK6,RYR1,SCN2A,SCNN1D,SLC1A2,SLC1A3,SLC1A6,SLC1A7,SLC6A1,SLC6A11,SLC9A5,SLC12A2,SLC12A4,SLC14A1,SLC15A2,SLC20A2,SLCO1A2,ACTR6" Drug 870_UP pyrvinium pamoate; Up 200; 1.25uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.00E-02 1.00E+00 4.73E-02 5.38E-01 40 177 "FAM131A,PPP4R4,N4BP2L1,ST3GAL5,USP2,SLC16A4,ARHGEF2,CLGN,GPR37L1,CHRNA4,CLU,PDE4DIP,MFAP3L,RASGRP1,OPTN,CALCRL,CDKL3,F3,F5,AMOTL2,SIGLEC8,SESN1,TDRKH,GRB10,GRIK2,NR3C1,GRM1,TJAP1,IL6ST,MAOB,NF1,RAB3IL1,PPM1E,EPN2,KIF21B,AHCYL2,TIMP4,PRMT8,UBE2H,VLDLR" Drug 2079_UP Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ALAD,APBB1,APBB2,ADAM15,BAIAP3,BTRC,CANX,ARHGAP22,QKI,AKAP12,CRY2,CSF1,DCAF4,SMG7,EFNA3,VPS26C,ZNF589,CAMKK2,TMEM8B,GCNT2,MSL3,IL6R,LIG4,NEK1,PLEC,STRN3,TMEM231,SH3TC2,ATG16L1,GAL3ST4,MAP6D1,MAPK12,TNIK,TSNAXIP1,GLT8D1,SAMSN1,NXT2,ST5,ZNF34,UGT8,SYNC,HPS4,NAV2" Drug 2346_UP Fenbufen [36330-85-5]; Up 200; 15.8uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "SYN3,NDRG2,AMT,SYNJ1,CDO1,HOMER3,IQCK,CREM,CSF1,FEZ1,SLITRK5,PPP1R16B,TBC1D5,DAPK3,FRY,C3orf18,COQ7,RASGRP2,PRKAG2,PDLIM5,CAMKK2,CELF1,GABRA4,ADAMTS8,MAP4,KCNK10,PENK,PMP22,LRRN3,PRKCZ,ITSN1,FUZ,CCDC88A,MYH15,ZBTB43,TACR1,KAZN,PSD3,CRTC1,THBS4,SLC44A1,TK2,TPM2" Drug 5101_DN Prednisolone [50-24-8]; Down 200; 11uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "BRAP,CDK10,MARCH3,SLC4A4,STX16,CANX,CCNT1,ARMC8,BAG4,TENM4,SOCS5,PDE4DIP,SLITRK5,TBC1D5,SMG7,DLG3,DPH1,EDIL3,EDNRA,HIPK3,MBNL2,TUBD1,F3,ERAP1,GART,SPIN1,HSF2,SHISAL1,IL6ST,KCNN1,RC3H2,PPP2R5C,CSRNP3,EMC1,BEX1,TROVE2,DIP2A,TRIM2,TRPS1,SSBP2,XRCC4,ZNF711,PHTF2" Drug 1547_UP Albendazole [54965-21-8]; Up 200; 15uM; HL60; HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "NDRG2,CNTNAP1,APBA2,GAS7,CFLAR,BMP7,CCNT1,CD86,TMEM184B,CNTFR,PPP1R16B,MED12,EFNB3,FAM13A,VPS26C,CEND1,PRKAG2,CAP2,GABRA4,MALT1,GNG3,AGFG1,NTRK3,OLR1,PDE4B,CDK14,RETREG1,GPSM2,LRP12,PPP2R5C,PRKAB2,PRPH,ARID4A,RNASEL,PREX2,ARHGEF40,CDK19,TSPYL2,ST5,EXOC7,AHCYL2,TPM4,VAV1" Drug 2947_DN Risperidone [106266-06-2]; Down 200; 9.8uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "NDRG3,MAP4K3,PPFIA4,APBB2,MAP7,RAB28,C2CD2,VCAN,PPP1R16B,SMG7,FAM13A,ING4,FLT1,POMT1,INPP5K,GPD2,LILRA2,STON1,DHX35,IL11RA,ZNF862,PIK3R1,PPP3CC,PTPRO,ZFP30,SLC2A5,ARFGAP1,KDM4B,WDTC1,ZCCHC24,ZSWIM8,NCDN,CEP68,VAMP1,CAMSAP2,KIAA1107,TCF7L2,AP4E1,ZMYND8,REEP1,TFIP11,EVI5,WIPF2" Drug 5566_DN 17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "AK2,C1QTNF3,LTBP4,APBB2,ATM,SYNJ2,CAMK2B,ARHGEF10,HDAC4,LYPD1,ATN1,SIDT2,EGR3,MRNIP,PLEKHO1,STX2,EZH1,FGFR3,SEPT9,GPR19,INPP5B,KCNH2,MATK,SLC11A2,MINDY2,PRPH,SYTL2,RIPOR1,RET,FBXW7,SLC6A8,SLC22A4,MAPKBP1,ZSWIM8,DNMBP,IQCE,TCF7L2,CABIN1,ZMYND8,UBTF,MAP3K12,WIPF2,MPPE1" Drug 4676_UP Testosterone propionate [57-85-2]; Up 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ADD2,AMPD3,ANK2,APBB1,RASL11B,SYNJ2,IL33,BTRC,DNAJB5,PLPPR4,DTNA,CELSR3,MRNIP,APC2,KIAA1109,PRELID3A,GAB1,ALDH1L1,GPR75,GRM7,KCNJ4,LAMA2,MT1M,NF1,NNAT,NPPA,PDE2A,PDE4D,RAB3IL1,RAD51D,FBXW7,MRAS,SLC9A5,SNCA,SPTB,ATP10B,ARC,TAL1,SEZ6L,TPM1,TPM2,CHST5,ZMYND8" Drug 7080_UP GW8510; Up 200; 10uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "SERPINA3,ADD1,AK2,AMT,CDC42BPA,APC,GAS7,APLP1,APP,ATP2A2,ADAM23,BMP7,FUBP1,MTMR2,SGCE,RASSF2,DTNA,FECH,EFCAB2,CELF1,GAD1,GALC,INPP5K,COPS8,ATXN2L,HSF2,KIFC3,MAP4,BCO1,POLR2F,PPP2R5C,PRPH,ROM1,RPS6KA2,PAQR6,SFPQ,PEX26,WDTC1,NSFL1C,ZMAT3,TNNT1,MICAL1,LAT2" Drug 5351_UP Ceforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "AP2A2,ALCAM,KCNAB2,EPB41L5,BCL7A,CFLAR,KSR1,SCAPER,CA12,CAMK2B,B4GALT6,TAOK2,QKI,PDE4DIP,EDRF1,GIT2,RABGAP1L,MED12,ACOT8,DTNA,FECH,FER,RASSF8,HNMT,IPO5,MAP4,TM6SF1,ZNF862,RETREG1,PLCD1,LRP12,TMEM104,RGS10,FOXRED2,ITSN1,ANKRD6,BTBD7,ASTN2,EXOC7,AHCYL2,TEX15,ZNF34,MVB12B" Drug 3054_DN Monobenzone [103-16-2]; Down 200; 20uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ARID1A,PLA2G6,AZGP1,KSR1,CDH8,ARHGAP33,RAB33A,SLITRK5,KIAA0753,FAM13A,ENO2,ZNF589,C1orf61,EFCAB2,KHDRBS3,SEPT9,GCNT2,PSRC1,GPM6B,DIDO1,SPACA9,GRM1,ATXN2L,MGAT3,AFDN,MYO6,GPSM2,PLEC,STRN3,PTCH1,RGS3,SCN2B,WDTC1,SPTAN1,RAP1GAP2,EXOC7,CAMSAP2,KIAA1107,RPGRIP1L,RBFOX2,FLRT2,XRCC4,ZNF225" Drug 5608_DN Butylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ADD3,KIDINS220,BIN1,APBB2,GAS7,AQP4,CAPRIN2,GYG2,CACNA1I,CBFA2T2,UBE2L6,ZFYVE9,AKAP7,KIAA0513,MAML1,SMG7,DRD1,STX2,SCARA3,GABRA2,DISC1,TXNL4A,GLYR1,GNG3,TDRKH,ZNF862,NEUROD1,NUMA1,PCDH9,PDE3B,PPARA,RAD52,PPP4R3A,WDTC1,PLCB1,SEMA4A,KIAA0930,TCF7L2,TGFBR3,BHLHB9,PARD3,CABIN1,LMF1" Drug 921_UP rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "TRMT9B,AMT,BAIAP3,LDLRAD4,CA4,CACNA1D,HIP1R,DNAJB5,AKAP7,FAM149A,COL4A5,COL9A3,RCHY1,RGS6,FEZ1,DZIP3,GREB1,DBT,MAGI2,DMPK,DSCAM,ST3GAL6,ZNF589,ERAP1,GPER1,CNTRL,IFI16,ZNF862,NF1,GRAMD1C,CNNM2,SIDT1,RGS12,RNASEL,ANKRD6,WDTC1,ZCCHC24,TCF7L2,RUNDC3B,ZMYND8,RPRM,KCNK12,ITM2C" Drug 7238_UP Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "LGR5,ADGRB3,SCAPER,GYG2,CACNB4,ARHGEF2,AKAP7,CSF1R,NOS1AP,HDAC9,SLC12A6,TENM1,EML1,KIAA1109,BAIAP2,FHL1,FLNC,OGA,SPACA9,GRM8,KCNC1,KCND3,KCNJ3,KCNN1,KCNN2,LIG4,AFDN,CNOT4,NPPA,NUMA1,LRRN3,SUGCT,FAM214B,KANSL3,SLC11A1,PCDHA5,CHST8,AMACR,WIPF1,LAT2,ITM2C,FAM13C,PHTF2" Drug 4450_DN 17-AAG; Down 200; 1uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "APBB2,ADGRB2,CDK5R1,SCARB1,ASIC3,NRXN3,RAB26,CNTN1,AKAP7,HAPLN1,SPOCK3,HIPK3,LRRC23,NCALD,ZNF589,IQCG,TRAF3IP2,GBX2,KCNMB4,GPM6B,STON1,HAS2,ICA1,SCIN,ITPKA,ZNF862,PFKFB4,WDR25,RIPOR1,ZDHHC14,RGS10,TMEM206,SLC1A7,PEX26,ARHGEF40,BTBD7,KDM4B,DDN,CEP68,KIAA1107,TIAM1,TNS1,RPRM" Drug 5726_DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "AP2A2,AK2,ALAD,AMPD2,CDC14B,SEMA4G,ALDH7A1,SYNJ2,KYAT1,CBFA2T2,ASIC3,CHN2,RAB28,SULT4A1,SDC3,SIRPA,KLHL3,DLG3,TUBB4A,BAIAP2,USP19,ADAM22,ZNF862,RETREG1,RAB3A,FAM184A,GAL3ST4,SEC61A2,MYH14,GSTCD,CCDC25,IL17RB,SNCA,TNIK,DOK5,KDM4C,SYT11,TRIM2,CHST8,BHLHB9,CADM1,UGT8,URM1" Drug 6716_DN Glycocholic acid [475-31-0]; Down 200; 8.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ACLY,ADCY6,KIDINS220,CDC42BPA,APC,CDK10,CDK13,ASPH,ATM,CANX,ARHGEF2,SOCS6,CHM,QKI,HOMER3,TBC1D5,FCF1,MBNL2,IRAK4,TUBD1,EPB41L2,SPEG,ETV1,FER,GPD2,CNTRL,NDP,CNOT4,PFKFB2,PPP5C,RAD51D,SH3TC2,TMEM156,SAFB,ASAP3,EMC1,TCF4,TPM1,MICAL1,NSD2,XRCC4,ZBTB14,PHTF2" Drug 7375_DN Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "APLP1,ALDH4A1,MYRF,CLCN3,HOMER3,BAG4,CSNK1E,RCAN1,COQ7,SCARA3,GAD1,GART,COPS8,GLS,HTATSF1,GPD2,RNFT2,GUCY1B1,INPP5B,KIF2A,KIF5C,SLC11A2,NUMA1,SNX10,PLCD1,RC3H2,PEX5,RGS10,LGR4,SH3GL2,CDK5RAP2,LIMCH1,SS18,FCHO1,FAM168A,AHCYL2,ZNF34,TIAM1,CBX5,TRPC1,TSN,TRIM9,PHTF2" Drug 4226_DN "Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "CDC14B,ALDH4A1,ADGRB2,RAB26,ENTPD4,CREB5,VCAN,SDC3,ATN1,EDN1,PLXNC1,SORBS3,RGS17,SEMA4D,CINP,FAM49B,FYN,SEPT9,RUNDC3A,KCNMB4,ATXN2L,MAPT,AFF1,NUCB1,OGG1,PDE4B,PLXNB1,PPARA,MAPK7,SAMD9,ZSCAN32,PTPRB,ZNF821,FRMPD1,PPP4R3A,KANSL3,BTBD7,TPM2,ZMYND8,WNT7A,XRCC4,NUP214,TIGD6" Drug 5603_UP wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "NDRG2,C1QTNF1,DNAH17,CFLAR,SCAPER,CA4,CAMK2B,CD86,NDST3,CLCN4,MYRIP,NRG2,CSF1R,GREB1,DYRK1A,EDNRA,ING4,MTSS1L,FGFR3,FHL1,GCNT2,STON1,GPER1,SPACA9,NR3C1,GUCY1A2,KLF12,KCND3,ADAM22,SLCO1C1,NUMA1,PCSK2,PURG,MAPK10,NLGN1,PDZD2,CDK19,ROBO3,TRIM2,TNS2,BEX4,XRCC4,SSPN" Drug 1792_UP Meticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "MTUS1,CDC42BPA,SHROOM2,LRRFIP1,ARHGAP22,ZFYVE9,CLU,COL9A2,PLCH2,MATR3,PLPPR4,SPOCK3,DYNC1I1,APH1A,FGF13,FAM49B,B4GALNT1,GFRA1,TXNL4A,MSL3,GRM1,HMGB1,HSP90AA1,MDFI,CNOT4,SLC11A2,LRP12,PRKAR1B,MAPK7,ELOVL2,FAT4,RET,NUDT11,ZNF821,PEX26,KDM4C,DBNDD2,JMJD6,COBL,KIAA0930,ARHGEF12,XRCC4,MAP3K12" Drug 5602_DN Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "APBA2,GAS7,PDE8B,CACNA1G,BTRC,CRLF1,CACNA2D2,CSF1,JAKMIP2,C2CD2L,HIPK3,EFNA3,EIF5,FOXG1,GAP43,ADAM28,MALT1,ADAMTS13,GRIK5,CACFD1,NR3C1,KCNH2,SETD4,PPP5C,PRPH,RELN,FAM120C,RAB3A,RAD52,ZFHX4,FBXW7,MAP6D1,WLS,LIMCH1,MAPKBP1,DOK5,JMJD6,WSCD1,AHCYL2,TGFBR3,TNS1,PLSCR4,GAN" Drug 4315_DN Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "AP2A2,AK2,MRTFA,APOC1,SEMA4G,MARK4,ATM,B4GALT6,HOMER3,CRMP1,NCOR1,VCAN,PPP6R2,ING4,ETV1,FAM49B,OGA,GABRA2,DISC1,GLS,POLL,GSTM5,ITGA7,JAK2,VWA5A,MDFI,NTRK2,PDE4D,NLE1,RGS10,IL17RB,SUPT20H,ASAP3,SLC1A3,FAM214B,UNC5B,ATP11A,SYNE1,RPRM,VIPR2,LMF1,SPHK2,PARP6" Drug 1830_UP Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "ABR,ASPH,BCL2L2,CFLAR,CA12,SOCS6,ZFYVE9,AKAP12,CTH,ZFYVE16,DBT,HP1BP3,FHL1,TRMO,TPK1,INPP5K,ARFIP1,GPR17,CNTRL,HNMT,IFI16,MATN3,MBNL1,NFYA,NPR2,APTX,RAD52,RGS4,TTLL7,FAM192A,ATXN1,ITSN1,CCDC88A,SS18,MAPK8IP3,SYT1,TNS2,TRIO,ZKSCAN5,UBE2H,SYNC,NT5M,EVI5" Drug 1816_UP Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "KIDINS220,AK2,LTBP4,NCOA1,ALDH4A1,ATM,TAOK2,SLC4A7,AATK,MATR3,FCF1,APH1A,ING4,TUBD1,PLEKHO1,ETV1,DPYSL4,GPD2,HNMT,SHISAL1,KCNK1,MATN3,SCAMP5,CNOT4,CLDN11,PTN,KCTD17,ZNF671,FAM192A,ITSN1,NUBPL,RAB3GAP1,SLC20A2,DOK5,LHPP,CLASP2,CAMSAP2,SATB2,PSD3,METTL3,HIRA,EMSY,NT5M" Drug 6207_UP Clotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.01E-02 1.00E+00 4.73E-02 5.39E-01 43 193 "AP2A2,ATM,ATP1A3,MPDZ,CFLAR,MTMR3,CACNA1I,LDLRAD4,CACNB2,FAM189A2,DNAJB5,CREM,PARD6A,DMTN,FER,GABRA2,GLRB,POLL,LPAR4,GRB10,BTN2A1,RASSF8,HNMT,IL6ST,NPTX1,NUCB1,PDE1C,SERPINE2,SAMD9,VPS13C,PTCH1,TSPYL2,ARC,ANKRD12,IQCE,TRIM2,CHST5,ZNF384,ZMYND8,VIPR2,VLDLR,SEMA3B,SLC17A7" Drug CID000000136 "5,10CH=THF" Stitch 1.01E-02 1.00E+00 4.74E-02 5.39E-01 13 42 "BRAP,AMT,CBS,CRY2,AGAP2,NEURL4,MTHFD2,GART,ALDH1L1,MTR,PIK3R1,FXYD1,SHMT2" Drug CID000004850 piribedil Stitch 1.01E-02 1.00E+00 4.74E-02 5.39E-01 13 42 "ADORA2A,ADRA1D,ADRA1B,DRD1,MAPK3,MAPK4,MAPK7,MAPK8,MAPK9,MAPK10,MAPK12,MLST8,TRH" Drug CID000000134 gamma-butyrobetaine Stitch 1.01E-02 1.00E+00 4.74E-02 5.39E-01 13 42 "ACADM,BBOX1,ALDH7A1,CLU,ZMYND10,CPT1C,IDH3A,OGDH,TMLHE,SHMT2,SLC22A4,SP2,XPO1" Drug CID000004355 AC1L1HZ7 Stitch 1.01E-02 1.00E+00 4.74E-02 5.39E-01 13 42 "APLP1,CA4,CAST,ZMYND10,GFAP,MAPT,NFE2L2,PKM,MAPK10,SST,SYN1,SYN2,UBC" Drug CID000002196 aniracetam Stitch 1.01E-02 1.00E+00 4.75E-02 5.40E-01 31 130 "AGT,LGR5,ARNTL,KSR1,CBR1,CSNK1E,NR1D2,SPEG,GABRA5,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN2C,GRIN2D,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,WIF1,NPY,ADHFE1,MKRN3,AMN1" Drug ctd:C002802 tungsten carbide CTD 1.01E-02 1.00E+00 4.75E-02 5.41E-01 36 156 "OSBPL6,PPFIA4,ASGR1,CDH2,CTH,MAGI2,ATL1,ENO2,DPYSL4,IQGAP2,GPT2,HSPA1L,MT3,NAP1L2,NFE2L2,ALDH1L2,PFKFB4,PSAT1,MAPK3,PTPRZ1,RGS3,TTLL7,RIMKLA,S100B,SGK1,SLC1A2,SORCS3,SOX2,SPP1,ATP10B,VWCE,SIRT1,UCHL1,DNAJC12,VLDLR,NLRP3" Drug ctd:C025589 ochratoxin A CTD 1.02E-02 1.00E+00 4.78E-02 5.44E-01 170 916 "SERPINA3,ABAT,ACTN1,AGT,AK2,ALAD,SPOP,MRTFA,APAF1,APOC1,ASCL1,ASPA,CHRD,ATP2A2,AZGP1,BARD1,BID,CFLAR,LDHD,CDK5R1,FUBP1,CALM1,CAMK2A,CAMK2B,RGN,AIFM1,CD86,CDO1,CHRNB2,SLC22A6,CLU,CNN3,RCHY1,CP,CHD1L,CPS1,AKAP12,CRY2,ABCG1,CRYM,CS,PDE4DIP,CST3,CTH,CX3CR1,CYBB,TBC1D5,DGKG,JAKMIP2,POM121,DLG2,DNAJB6,EEF1A2,RASGRP1,EEF1D,EGFR,EMX2,ENO2,COQ7,ERBB4,F3,F5,ABCA8,TESK2,TACC2,ARFGAP2,DLL3,STAG2,HBS1L,GFAP,GGT5,GHR,GJB1,GK,GLUL,GPT2,CNDP1,GPR17,NUDT21,EML4,RAPGEF4,GRIA1,GRIA2,DIDO1,GSTT2,HNRNPK,HSD17B1,HSP90AA1,IDH3B,IGF1,IGFBP1,HES5,ITGA7,ITGAM,KCND2,PIK3AP1,MBP,KITLG,MOG,COMMD5,MSRA,NEFH,NEUROD1,NF1,NFIA,NFE2L2,SLC11A2,NRDC,OGDH,OGG1,PAK3,PDCD2,PDGFRA,PDPK1,PFKP,PGAM2,ABCB1,PIK3CD,PMP22,NECAB2,SEPT4,PPP3CB,PRKCB,MAPK3,MAPK8,MAPK9,PROX1,NDUFS7,APTX,PTK2,SPDL1,PYGM,RBBP6,RDX,RFX5,RPE,MAPK12,SBF1,SCAF8,SGK1,SLC1A2,SLC1A3,SLC2A5,ELMO2,SLCO1A2,SOX2,SPATA7,KIF21B,SOX10,SPP1,SRPK2,MPRIP,KANK1,JMJD6,TAF9,TF,ZMAT3,TJP1,TLR4,PIK3R5,TPM3,TSC2,TUBB1,RPRM,PITPNB,VLDLR,CLDND1,MICU3,ZNF213,CPNE4" Drug ctd:D013893 Thiram CTD 1.02E-02 1.00E+00 4.81E-02 5.47E-01 104 533 "CPNE2,ACADM,ACHE,ADD1,ADD3,BRAP,AMPD3,CASK,ARRB2,BCL7A,CAMK2A,CANX,CH25H,CARS,RGN,CD86,SLIT2,QKI,COL9A1,COL9A2,CREM,HINFP,GPSM1,TMEM170A,DAPK3,AIF1L,ELMO1,ABI1,GNE,EFNB3,MBNL2,KMT5B,PLEKHA1,EYA1,SH3YL1,FER,FGFR3,PCYOX1,SYNCRIP,FOXM1,FLT1,JKAMP,ZCCHC17,SMC2,STAU2,NCKAP1,GATM,RND1,GLDC,GLYR1,NR3C1,CLASRP,ATG4C,HPS5,ELOVL5,HPSE2,HPCA,JAK1,KHK,CREG2,LMO1,SCG3,NAP1L1,NCAM2,NFIA,NME4,NUCB1,OPA1,PDGFRA,OLA1,GPSM2,EPN1,TATDN3,PPP2R5C,RASGEF1B,PRKCB,PRKCG,PSMD13,DPF2,UEVLD,WLS,SH3GL3,SEC31A,ANKRD6,PKNOX2,SLC12A2,EFHD1,SMARCA4,CLUAP1,KIF1B,SYNE2,ANKRD12,TBX15,TCF4,TCF12,AHCYL2,TK2,TMPO,SH3GLB2,XKR7,TRIM16L,KAT6A,NLRP3,VANGL2" Drug CID000177355 olympus Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "LGI1,TBPL1,DNAH9,EVL,PSD2,HPSE2,SHANK2,SLC14A1,ARHGEF12,UPF3A" Drug CID000089440 AHTN Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "CRLF1,ABCG2,ARHGAP32,AGAP2,ATP8A2,LYVE1,LIFR,MX1,PLEC,CA10" Drug CID000005685 WB4101 Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "ADRA1D,ADRA1B,ADRB2,P2RX6,CHRM1,KCNJ5,P2RX7,GPSM2,SYP,TTPA" Drug CID000068245 delphinidin Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "KCNH8,ALDH7A1,LRBA,EGFR,FOXM1,RAPGEF1,GRIK4,MAPK9,MAPK10,GORASP1" Drug CID000000038 ketopantoate Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "SERPINA3,PLEKHB1,CLU,EGFR,ERBB2,FLT1,HSP90AA1,NEUROD1,PTHLH,TRO" Drug CID000129228 rufinamide Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "CACNA1I,CACNA1G,CHN1,SV2A,GRIA1,GRIA2,GRIA4,KCNQ2,KCNQ3,LSS" Drug CID000072127 AC1L2HGV Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "CHGA,MCHR1,IGF1,MYCN,SST,SSTR1,SSTR2,SYP,SMUG1,VIPR2" Drug CID000004622 oxibendazole Stitch 1.03E-02 1.00E+00 4.83E-02 5.49E-01 10 29 "TBPL1,TUBD1,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,TUBB2A,TUBB1,TUBA1A" Drug ctd:D009638 Norepinephrine CTD 1.03E-02 1.00E+00 4.84E-02 5.51E-01 39 172 "ADRA1D,ADRA1B,ADRB2,AGT,ATP2A2,CREM,SLC29A4,DRD1,EDN1,EDN3,EDNRA,EDNRB,EGFR,F3,FGF1,FOXO3,PPARGC1A,GK,GNAS,IGF1,KCNMA1,MAOB,MYH6,MYH7,NPY,NPPA,PCSK1,PCSK2,PDYN,PLCD1,PPARA,PRKCZ,MAPK3,MAPK8,MAPK9,MAPK10,S100B,SLC8A1,PLCB1" Drug CID000003397 flutamide Stitch 1.03E-02 1.00E+00 4.86E-02 5.53E-01 35 151 "AGT,DYNLL1,ATM,BCHE,NGB,MYOM2,SEPT7,CLU,MAP4K4,NCOR1,NCOR2,GSDME,ELAVL3,ZMYND10,FGF1,FLT1,GHR,PPARGC1A,LYVE1,GPT2,NR3C1,HBA1,HSD17B1,IGF1,SMAD1,CCDC80,DDX25,MYO6,NDUFA5,CLDN11,SOX8,SAFB,SST,TF,TNR" Drug CID000104735 compound 48/80 Stitch 1.03E-02 1.00E+00 4.86E-02 5.53E-01 35 151 "ADORA3,ATP1A2,ATP1A3,ATP2A2,ATP2B1,ATP2B2,ATP2B3,ALDH7A1,CALM1,KRIT1,CHRM1,PLCXD3,ATP2C1,B3GAT1,PLCD4,MAP4K5,HRH3,HNMT,IGF1,MARK3,KITLG,NF1,PLCB2,PLCD1,PRKCB,PRKCG,PTAFR,SAFB,CDK5RAP2,SP4,SST,PLCB1,TAC1,TAC3,TACR1" Drug 6298_UP Azacyclonol [115-46-8]; Up 200; 15uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.04E-02 1.00E+00 4.87E-02 5.54E-01 42 188 "ARID1A,SEMA6A,PPFIA3,PDE8B,HIP1R,ARHGEF1,CDH10,ABCG2,ABCG1,MAGI2,EFNA3,EFNB3,DMTN,STX2,RRAGB,TESK2,ZNF589,FGF1,TRAF3IP2,GRB10,CACFD1,KLF12,IL6ST,JAK2,MT1M,MX1,MYO6,CNOT4,PENK,PPP2R2B,ELOVL2,RGS10,SUGCT,TSPYL2,ARC,TK2,TRIO,AMACR,WIPF1,NT5M,EVI5,KCNAB1" Drug 5493_UP Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-02 1.00E+00 4.87E-02 5.54E-01 42 188 "SYN3,ADORA2A,AMPD3,BIN1,ANK2,HAP1,FADS2,QKI,FAM149A,PDE4DIP,ARHGEF4,GIT2,MED12,EFNA3,F5,ARMCX1,ATP8A1,DCTN2,RND1,CNTRL,IL6ST,INPP5B,LSS,PDE4A,PGAM2,PLCD1,PTPRD,FAM120C,ATG16L1,TTLL7,NEK11,RPS6KA2,ZNF821,PDZD2,CLSTN2,ZC4H2,TRIM2,CRTC1,PCDHA6,GPR161,FLRT1,SLC17A7" Drug 2896_DN Mometasone furoate [83919-23-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.04E-02 1.00E+00 4.87E-02 5.54E-01 42 188 "CDC7,SEMA6A,SCAPER,MAGI1,RCBTB2,SRSF11,LHX2,C2CD2,EXOG,VPS26C,SCML2,FGFR1,FGFR3,HBS1L,GPD2,CACFD1,ARHGAP19,HSF2,KCNH2,KHK,MDM4,MMP16,ADAM22,PCDH9,PDE3B,RETREG1,PLPPR1,RAD52,SUSD4,GTDC1,SFPQ,KIF16B,EPN2,TCF7L2,RPGRIP1L,PCDHA6,AHCYL2,DICER1,CHST8,TMPO,MPPE1,PHTF2" Drug 6926_UP 17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.04E-02 1.00E+00 4.87E-02 5.54E-01 42 188 "C1QTNF3,SYT13,BIN1,APOC1,ATP6V0A1,ST3GAL5,USP2,NEURL1,PLAA,AKAP12,DNAJC6,DMPK,COQ7,GAD1,GNG3,CACFD1,PTGDR2,KCNMA1,PACRG,AFDN,NAP1L2,NFYA,PDE4D,NECAB2,RGS12,HSPA4L,SH3BGR,FRMPD1,NLGN1,ANKRD6,IQSEC2,TSPYL2,POPDC3,SEMA4A,BEX4,PARD3,LILRA4,TRIO,DNAJC12,VIPR2,CLIP2,FAM13C" Drug CID000001281 hemi-BABIM Stitch 1.04E-02 1.00E+00 4.88E-02 5.55E-01 20 75 "ADGRB1,ADGRB2,ADGRB3,BAIAP3,CACNB4,B3GAT3,EBF1,ENO2,ERBB2,BAIAP2,FHL1,FOXG1,GABRA1,CNTN3,YY1AP1,TNFRSF19,LRRC4,TBL1X,SLC17A7,SLC17A6" Drug ctd:D010042 Ouabain CTD 1.04E-02 1.00E+00 4.88E-02 5.56E-01 29 120 "AGT,ARRB1,ATP1A1,ATP1A2,ATP1A3,CALB1,CANX,PPT2,CS,DRD1,EDN1,EDNRA,SGK2,GLRB,KCND2,KCNH2,LSS,NOS1,NPPA,ABCB1,MAPK3,MAPK7,S100B,SGK1,SLC8A1,RPGRIP1L,TRPC1,SGK3,CCDC14" Drug CID000001855 DHBT Stitch 1.04E-02 1.00E+00 4.88E-02 5.56E-01 29 120 "AMPH,MADD,SYNJ1,AP1M1,HIP1R,CHM,CLTA,CLTB,CLTC,CNTN1,SNAP91,DNM1,DNM2,DNM1L,ENO2,VTI1B,MX1,PCSK2,PIK3C2A,EPN1,PBRM1,RYR1,FUZ,SNCA,BDP1,TF,TK2,SCG2,HPS4" Drug CID009549299 EGFR inhibitor Stitch 1.04E-02 1.00E+00 4.88E-02 5.56E-01 29 120 "ADRB2,PROM1,BSN,NRG2,ABI1,EDNRA,EGFR,ELAVL3,EPS8,ERBB2,ERBB4,PTK2B,MSTN,IL6ST,MEST,NODAL,PIK3C2A,PIK3CD,PIK3R1,MAPK3,MAPK9,PTHLH,PTH1R,PTK2,MAPK12,PDZD2,ZEB1,THRA,SPHK2" Drug CID006857426 Phosphoryl Stitch 1.06E-02 1.00E+00 4.95E-02 5.63E-01 47 215 "ACHE,NME5,AK2,MAP4K3,PDXK,CASK,CDK13,ATP2A2,ATP2B1,ATP2B2,ATP2B3,BCHE,BCS1L,LRBA,MAGI1,CHD1L,CSNK1E,CSNK1G3,AK5,ATP2C1,GCK,GK,GLUL,STON1,PTPN5,HP,HPR,SCRT2,ITPKA,LIG4,MYL3,NME4,PC,PFKFB2,PFKFB3,PFKFB4,PFKP,PGAM2,PKM,PRKACB,NDUFS7,PTH1R,RNASE1,RPS6KA2,SLC2A5,SLC6A7,TK2" Drug CID000003343 fenoterol Stitch 1.06E-02 1.00E+00 4.95E-02 5.63E-01 16 56 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,BOC,PLEKHM1,EDNRA,EDNRB,NEUROD1,MAPK3,MAPK4,MAPK7,TAC1" Drug CID000007046 tetrahydroisoquinoline Stitch 1.06E-02 1.00E+00 4.95E-02 5.63E-01 16 56 "BOC,DRD1,LOXL3,GRIA1,GRIA2,GRIA4,GRM3,HRH3,HTR2A,MAOB,ABCB1,PTPRN2,SEPHS1,SST,APOM,RGMB" Drug CID000005672 vinorelbine base Stitch 1.06E-02 1.00E+00 4.96E-02 5.64E-01 21 80 "RHBDL1,ABCG2,SLC4A7,EXOG,EGFR,TUBD1,ERBB2,TUBB3,TUBB4A,TUBA8,TUBA1C,TUBB2B,STMN1,MAP6,MX1,ABCB1,SLC12A2,TUBB2A,TUBB1,VGF,TUBA1A" Drug CID000002477 buspirone Stitch 1.06E-02 1.00E+00 4.96E-02 5.64E-01 21 80 "ADCY2,ADCY5,ADCY6,ADCY8,ADRA1D,ADRA1B,ADRB2,SLC22A6,DRD1,STX2,ZMYND10,LOXL3,GRM5,HTR2A,HTR5A,KCNK3,MAOB,NPY,OXTR,S100B,SOX10" Drug CID000486165 AC1LADSF Stitch 1.06E-02 1.00E+00 4.97E-02 5.65E-01 38 167 "ASCL1,NRP2,CACNA1A,RGN,CHRM1,CLTC,CP,CRYBB1,MYEF2,SNAP91,NTM,DNM1,GNE,DTNB,ST8SIA3,OLIG2,F8,FECH,MEX3B,IP6K2,CHL1,GNAL,HAS2,KCNF1,L1CAM,AFDN,NCAM1,NCAM2,PDE4B,PPP2R2B,PRODH,ROM1,NPAS3,JMJD6,TK2,TPM3,AP3B2,ST8SIA2" Drug 1234_UP "Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.06E-02 1.00E+00 4.97E-02 5.65E-01 38 167 "ABAT,ABHD6,ADRB2,ARNTL,ST3GAL5,CHN2,SLC4A7,ABCG1,PDE4DIP,CTH,KIAA0513,DNAJC6,C2CD2L,PLPPR4,EFNA3,RGS17,BAIAP2,FLNC,PNMA2,FYN,RND1,MMP16,PCDH9,PDGFRA,SERPINI1,RETREG1,RBBP6,RGS4,SH3GL2,SH3GL3,SYBU,TNIK,ELOVL4,RGL1,SYT1,COBL,DNAJC12,PLSCR4" Drug 1554_DN Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ATM,SLC4A4,CFLAR,BTK,RUNX1T1,KYAT1,CDC27,CREM,PPP1R16B,SIRPA,DNM1L,DENND4A,CAMSAP1,SEC23B,ZNF274,PRRC2B,JAK1,KTN1,LAMP2,MARK3,MATK,MBD1,MBNL1,MITF,NASP,NFYA,SETD4,TRHDE,DEF8,PEX5,PCMTD2,ZC3H14,ATXN2,SLN,SMARCA4,ZCCHC24,POGZ,KANK1,TAC3,TCF4,WDR7,GORASP1,XRCC4,ZNF24" Drug 1931_UP Amoxapine [14028-44-5]; Up 200; 12.8uM; PC3; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADAR,ADD2,ADORA1,CDC42BPA,APLP1,ARNTL,HIP1R,INA,CDH2,CHN1,CHN2,ZFYVE9,CLCN3,SLC4A7,CTH,RUBCN,RIMS3,RUSC2,DLG3,DPH1,ACOT8,ATN1,EFNB3,APH1A,GBX2,CYP46A1,INPP5B,KCNK1,NTRK3,CCSER2,RAB3A,RGS3,NEK11,ATXN2,TRA2B,ASAP3,BCAN,ZHX3,TSPYL2,SEMA4A,WSCD1,GPR161,PRDM2,MPPE1" Drug 3805_DN Fenbendazole [43210-67-9]; Down 200; 13.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "PPP4R4,SLC4A4,CBFA2T2,DNAJB5,RAB26,IQCK,ARMC8,TCEAL2,DAPK3,MFAP3L,EXOG,DUSP9,COQ7,DMTN,ZNF589,IQCG,PRELID3A,GAA,C1QL1,DHX35,SHISAL1,IL11RA,MAPT,MN1,NUMA1,OGG1,PDGFRA,KCTD15,PRPH,PTHLH,KCTD17,PAQR6,CSRNP3,IL17RB,ZNF821,ASAP3,ARHGEF40,CAND2,PLCB1,COBL,TBCEL,NT5M,TIGD6,AAAS" Drug 2471_UP Phenacetin [62-44-2]; Up 200; 22.4uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AGT,AMPD3,ARHGDIG,ALDH4A1,KIF1A,NRP2,KSR1,BMP7,CDK5R1,AKAP6,COL9A3,CREM,MICAL2,CNTNAP2,CTIF,CNIH3,MFAP3L,SV2B,DLG4,SEZ6L2,SPEG,OLFM1,TMEM8B,ATF7,RAPGEF4,GRIK5,KIF3A,L1CAM,SLCO1C1,NINJ2,PDE4D,PLP1,PTPRG,SEMA6D,STUM,EPN2,SHANK2,SLCO1A2,HECW1,SPTB,DOCK9,ATP13A2,TK2,TRPC3" Drug 1439_UP Nifenazone [2139-47-1]; Up 200; 13uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "EP400,MAP4K3,ATM,EIF4G3,CNOT8,DNAJB5,DCAF8,DCTN1,HP1BP3,KLHL3,KCTD3,MRNIP,BSCL2,DENND4A,CD320,HBS1L,TXNL4A,GLS,PADI2,MAP4,NPY,PLCD1,SIDT1,PTK2,C1orf109,BSDC1,CRTAC1,KBTBD4,SLC15A2,ELMO2,ZKSCAN3,ZSWIM8,ZC4H2,SS18,MLC1,TACC1,CRTC1,TLR4,PARD3,HIRA,XRCC4,WNK1,NUP214,RNF170" Drug 1804_UP Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "KIDINS220,LTBP4,APP,MARK4,BCL7A,MTMR2,HAP1,ZFYVE9,GPRASP1,TOX,CDON,FEM1B,FCF1,APH1A,ING4,EML1,SEMA4D,TRMO,CELF1,GAD1,SRCAP,BTN2A1,AGFG1,NFYA,CNOT4,MAPK8,ELOVL2,RAD51D,RGS10,KIRREL1,ATXN7,ZNF821,PPP1R9A,ST6GAL1,SLC4A3,ZKSCAN3,SPTAN1,NXT2,ELOVL4,ARHGEF12,TMEM121,TK2,TRPC1,XRCC4" Drug 6810_DN Sulfanilamide [63-74-1]; Down 200; 23.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ASPHD1,DOC2A,PPFIA3,MARK4,CFLAR,SYNJ2,SCAPER,CAMK2B,AP4M1,CACNA2D2,B4GALT6,VAX2,SH2B1,CSF1,CSNK1E,PDE4DIP,CNTNAP2,FAM169A,SDC3,EXOG,SLC12A6,DSCAM,EGFR,EIF4G2,SORBS3,ING4,FER,FGF12,FGFR1,POLL,ITPKB,KPNA5,KITLG,NUMA1,GON4L,RAB3IL1,SEC61A2,ROM1,RPS6KA2,SLC9A5,SHANK2,ZKSCAN3,SEMA4A,VGF" Drug 1003_DN nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "MRTFA,BTRC,KRIT1,NECTIN3,CRY2,NCOR1,HDAC4,GIT2,DBT,FBXL5,PARD6A,SGSM2,RABGAP1L,ING4,MRNIP,EML1,COQ7,FER,OGA,FYN,TXNL4A,HTATSF1,GRB10,HNMT,AGFG1,INPP5B,NEK1,PDCD2,PLEC,PRKAB2,APTX,DCUN1D2,SLC20A2,ZBTB43,ELOVL4,DIP2A,ASTN2,PDLIM2,IQCE,ARHGEF12,HEY2,CADM1,ZNF45,SMIM8" Drug 1569_UP Mifepristone [84371-65-3]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "NDRG2,APBA2,APP,CA12,KRIT1,CCNT1,PICK1,SLC4A7,CTH,DAPK1,EXOG,ANKMY1,F3,SEC23B,CAP2,MPP6,GLS,CNTRL,IFI16,KCNH2,GIT1,MX1,NCAM1,NTRK3,P2RX7,ENPP2,FTO,SLC25A23,PPP2R5C,PRPH,PTK2,TTC13,MSANTD2,EXD2,RPS6KA2,SH3BP2,EPN2,STXBP1,PLCB1,AGTPBP1,PARD3,HIRA,ZNF23,LMAN2L" Drug 5931_UP "ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "C1QTNF1,LTBP4,APBB1,APBB2,MARK4,SLC4A4,ADAM23,ASIC3,ARHGAP22,ABCG2,COL9A3,AK5,DRD1,EDNRA,IRAK4,EN2,STX2,SPEG,SCML2,FLT1,CSPG5,B4GALNT1,TMEM8B,STON1,GPER1,HNMT,MAPT,MARK1,POU3F4,RAD52,KCTD17,GSTCD,SLC1A7,ZNF667,CDK19,CEP68,PCDHGA10,TK2,CABIN1,TNS1,KLC2,PARP6,SMIM8,DPF3" Drug 1205_DN "ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "MTUS1,C1QTNF1,BIN1,OGT,APBB2,APP,MARCH3,SYNJ1,KYAT1,CDH2,LHX2,HOMER3,AATK,PPP6R2,RUSC2,SORBS3,RGS17,EPB41L1,SPEG,FGF1,ANKFY1,AHDC1,GLYR1,CNTRL,MUM1,DHX35,IL6R,MIA2,SCAMP5,MPP2,NF1,POLG,PPP3CC,PRPH,RGS10,ZC3H14,MAP6D1,SH3GL3,ASAP3,LIMCH1,ZBTB43,TCF4,TK2,RBFOX2" Drug 3346_DN Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AP2A2,PLA2G6,ALCAM,KCNAB2,APLP1,PPP4R4,ATM,MTMR3,GYG2,BTRC,ARHGAP33,ZFYVE9,SLC4A8,SH2B1,CRY2,DBT,RABGAP1L,NCALD,FGFR3,EFCAB2,PRELID3A,SRCAP,MALT1,GNG3,GNG4,TDRKH,SPACA9,NR3C1,KCNJ5,VWA5A,NF1,NTRK2,CDK18,LRP12,PRODH,FAM184A,CCDC25,ARFGAP1,WDTC1,TCF7,TCF7L2,VIPR2,XRCC4,SMIM8" Drug 6351_DN Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADD1,C1QTNF1,OSGIN2,NFS1,CDC27,SLC4A7,NRG2,SIRPA,DNM2,SUGP2,AASS,SPEG,F3,ACSL4,FHL1,TRMO,ZMYND11,ERAP1,GART,GPM6B,GSN,HMGCR,SHISAL1,L1CAM,MEIS1,NEK1,PRPH,SYTL2,PTPRN2,RGS10,SH3BGR,FUZ,ARHGEF40,SHANK2,TNIK,ELOVL4,VPS13A,TRIM2,AHCYL2,TPM1,WNT7A,XRCC4,ACTR3B,RNF170" Drug 222_UP "LY-171,883; Up 200; 1uM; MCF7; HG-U133A" Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "BIN1,OGT,APP,CDK10,DNAH17,BACH1,SYNJ2,CACNA1I,KRIT1,CHGA,IFFO1,SIPA1L1,SGK2,CDKL3,STAU2,AHCYL1,ZNF276,LILRA2,GPR37,KLF12,KCNB1,KCND3,MBP,MIA2,NNAT,OPCML,GPR173,PFKFB2,EPN1,SMIM7,PLXNB1,MAPK8,RAD52,TCP11L1,FOXRED2,FNDC3A,KBTBD4,CXXC4,IFT122,IGSF9B,CDH22,LMF1,XRCC4,MVB12B" Drug 4362_UP Tolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ACTN2,KDM5D,AGT,AMPH,APOC1,BAIAP3,ARHGEF2,CRMP1,VCAN,CNTNAP2,RIPOR2,SPOCK2,BRINP1,JAKMIP2,ECM2,EDNRA,EPHB1,NRN1,EFCAB2,FYN,GNAO1,ADAMTS13,GRM8,HPSE2,KCNN1,TAGLN3,MYT1,OGG1,LRRN3,RAD52,RORB,KCNIP1,SLC1A7,SLC8A1,ZNF415,IZUMO4,CDK19,AJAP1,SLC19A3,SEZ6L,TPM3,SCG2,KCNAB1,GJC2" Drug 7452_DN Trazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AK2,ALAD,APAF1,NCOA1,ALDH4A1,LHX2,RAB28,HOMER3,ARMC8,SLC4A7,CTNND2,PLEKHO1,EPB41L2,DLC1,CINP,ERAP1,DIDO1,HSD17B1,KCNJ3,LIG4,MAP4,NF1,TNPO2,FSD1,PRODH,RAP1GDS1,CCDC25,TCP11L1,FERMT1,FBXO11,SMTN,ZKSCAN3,TTC17,MAPKBP1,FNBP1,EMC1,ZBTB43,SPART,CLASP2,TACC1,TPD52,NPL,SMIM8,JMJD1C" Drug 3224_DN Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ABHD6,CDC42BPA,ARRB1,RGS20,CRLF1,TAOK2,HOMER3,FAM169A,DAPK3,TSPAN5,BAIAP2,FHL1,OGA,SEPT9,GLS,POLL,GNG4,CACFD1,GRM8,RNFT2,HNMT,INPP5B,ITPKB,KHK,MAP4,TM6SF1,NASP,CNOT4,PCDH9,RALGDS,ROM1,ZNF821,ITSN1,FUZ,SLC1A7,TROVE2,THSD1,TNS2,CABIN1,CDK20,ZBTB14,EMSY,HPS4,PCBP4" Drug 4002_DN Ginkgolide A [15291-75-5]; Down 200; 9.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADCY6,AP1B1,ALAD,APC,MARCH3,MARK4,ALDH7A1,DNAJB5,RAB26,HOMER3,CRMP1,PPP6R2,ARHGAP24,MFAP3L,HSD17B14,LRRC23,GNAS,GPD2,TDRKH,GUCY1A2,MEF2C,ZNF862,PAK3,PBX1,PDE4D,PDPK1,CNTLN,PTHLH,PID1,RALGDS,FAT4,SUGCT,SCN8A,IL17RB,KDM4D,ARHGEF40,JMJD6,ARHGEF9,DOCK9,XRCC4,TRIM9,MAP3K12,MPPE1,UBE3B" Drug 1322_UP "Cephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; HL60; HT_HG-U133A" Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ABHD6,BIN1,ASPH,NCOA1,ATP2A2,C5,MYRF,KYAT1,LARGE1,TAOK2,RAB33A,ARHGEF10,PPP6R2,ZFYVE16,CTIF,FCF1,RASGRP2,NCALD,KAT8,ZNF589,CAMSAP1,SEPT9,ALDH1L1,RND1,COPS8,ELOVL5,NLE1,PMP22,PTCH1,RIPOR1,FUZ,SLC1A3,SLC1A7,BTBD7,DOK5,SPTAN1,STX1A,ADGRL3,KCTD2,TNS1,ZMYND8,HIRA,ZNF32,UBE3B" Drug 5006_DN Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ASPHD1,NME5,SRPX,APBA2,APOC1,APP,RIMS3,SGSM2,E2F5,CNNM1,EFNA3,EML1,ACSL4,RACK1,FGFR3,SEMA4D,TDRKH,GRB10,NR3C1,HNMT,ITPKB,ADAM22,NF1,CNOT4,PRODH,WDR25,RGS10,SH3BP2,SLC1A7,PEX26,SPTAN1,TTBK2,EXOC7,IQCE,RPGRIP1L,ARHGEF12,CHST8,TP53BP1,FAM155A,VGF,KLC2,HPS4,MPPE1,KAT6A" Drug 4817_DN Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ARNTL,MARK4,ATM,LHX2,RAB28,HOMER3,ARMC8,PDE4DIP,MATR3,MFAP3L,EDNRA,FEM1B,FCF1,OPTN,RGS17,SEC24B,MPP6,ERAP1,EML4,MAP4K5,DHX35,BRINP3,KCNJ3,IPO5,MBNL1,NFYA,SLC11A2,PDE3B,RETREG1,GON4L,PEX5,RBBP6,SLC20A2,WASHC4,DOCK9,SLC44A1,NPL,RUNDC3B,HIRA,WRN,CLDND1,XRCC4,MPPE1,RNF170" Drug 1108_DN "leukotoxin B (12,13-EODE); Down 200; 0.2uM; MCF7; HT_HG-U133A_EA" Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "BRAP,OSBPL1A,EP400,NCOA1,STX16,MTMR2,CCNT1,SYNGR3,RAB28,CLCN3,HOMER3,SMARCAL1,DCAF8,DBT,C2CD2L,DMTF1,ACOT8,ABI2,EGR3,SORBS3,VPS26C,FGFR1,SARAF,MALT1,GLS,FERMT2,GRB10,IGSF1,KIF2A,CCSER2,FSD1,DPF2,ZDHHC4,RGS3,EXD2,MAP6D1,RAB3GAP1,TACC1,PJA1,ZNF384,SSBP2,UBE3A,KLC2,ZNF32" Drug 2310_DN Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "SLC12A5,C1QTNF3,CDC42BPA,APBB2,BCAS1,ARHGEF1,ZFYVE9,NMT2,SMG7,TOM1,EFNA3,EGFR,MRNIP,EML1,LRRC23,ANKMY1,F3,ACSL4,KIAA1109,CAMSAP1,POLL,GRIK5,NR3C1,GRM1,MIA2,MPP2,ZNF862,PALM,STRN3,MBOAT7,PPP5C,TCP11L1,ZNF821,ZNF365,BTBD7,SMARCD3,SPTAN1,MAPK8IP3,ELOVL4,EXOC7,SLC44A1,VGF,LMF1,EMSY" Drug 7308_UP Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "DPF1,AK2,MRTFA,APBB2,ATP2B2,ALDH7A1,SYNJ2,CA12,CBFA2T2,SOCS6,NMT2,QKI,CRY2,CTNND2,HDAC9,EDIL3,CSPG5,GAD1,DISC1,ALDH1L1,GPER1,ATXN2L,IFI16,MDFI,MYO6,NF1,OPCML,PDE1C,KCTD15,ZSCAN32,ACSS3,CCDC40,RAD52,SCG5,ASAP3,SNCA,ZHX3,ZBTB43,ATP10B,THSD1,TBCEL,RPGRIP1L,CRTC1,XRCC4" Drug 7416_UP Cortisone [53-06-5]; Up 200; 11uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "C1QTNF3,AMPD3,CFLAR,FUBP1,CAMK2G,USP2,CRLF1,FADS2,DNAJB5,COL4A5,PDE4DIP,MFAP3L,HIPK3,FYB1,SYT17,INPP5K,SRCAP,MALT1,TXNL4A,POLL,GSN,KCNH2,KCNN1,SETD4,GRAMD1C,RIPOR1,RAB3A,RAB3IL1,RASGRF1,RGS12,SH3BGR,ITSN1,ASAP3,SLC1A7,SHANK2,SCMH1,SNCA,ZHX3,ARHGAP26,CLSTN2,VAV2,VLDLR,LMF1,MAP3K12" Drug 6278_UP Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADORA2A,AMT,SEMA7A,APBA2,BCAS1,AQP4,MARK4,BCL7A,ST3GAL5,LDLRAD4,CACNA1D,RAB28,CSF1R,MFAP3L,DTNA,EDNRB,SEPT9,MALT1,GLYR1,ICA1,IL6ST,INPP5B,KCNJ4,MAP4,MID1,P2RY1,PDE1C,PDE3B,RAD52,ZCWPW1,RGS3,SMTN,SLC15A2,SLN,ARHGAP26,SPTAN1,MAPK8IP3,SEMA4A,DAAM2,PARD3,CABIN1,VAV1,KCNK12,SCG2" Drug 5478_DN Flufenamic acid [530-78-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ABHD6,SLC12A5,AP2A2,APBB2,KIF1A,BACH1,AP4M1,BAG4,PPP6R2,ZNF337,DBT,SPATA2,DMPK,TRAPPC9,RCAN1,PLEKHO1,EPB41L1,ANKMY1,TESK2,GPD2,RNFT2,ARHGAP19,IL6R,ITPKB,KHK,MEIS1,MKLN1,MPP2,SEC61A2,ZNF821,AMBRA1,SMTN,IFT122,PHLDB1,ARHGEF9,VPS13A,TAF6,PDLIM2,TCF7,ATP13A2,RBFOX2,CDK20,VGF,SSPN" Drug 2004_UP Khellin [82-02-0]; Up 200; 15.4uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "CDC42BPA,CNTNAP1,RIPK1,ADAM15,CA12,CALB2,CHRNB2,AATK,ECE2,KIAA0586,GIT2,EXOG,KCTD3,EFCAB2,UFM1,ATP2C1,TRAF3IP2,GNG3,GPR12,SPACA9,MPP2,NOS1,ENPP2,PLCD1,FTO,PMS2,PACSIN1,PTPA,RAB3IL1,RXRA,ZFP30,FAM214B,ARFGAP1,FNBP1,SPTB,ZC4H2,ERBIN,TCF4,DMXL2,CRTC1,ZNF24,HPS4,ST7,NUP214" Drug 523_UP "ICI 182,780; Up 200; 1uM; ssMCF7; HG-U133A" Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ACHE,NDRG2,BIN1,GAS7,ARNTL,ARRB2,CACNA1A,KALRN,CCKBR,ARHGEF6,SOCS5,ELAVL4,FECH,OLFM1,RASL10A,GAD2,RUNDC3A,GLS,GRK4,SOX21,FAM107A,GUCY1A1,IRF8,KCNJ10,L1CAM,ADAM22,MYL3,MYT1,FXYD7,PRKAR1B,ST6GAL1,SLC11A1,SLC15A2,SLN,CDK5RAP2,SNCA,FAIM2,DOK5,ZC3H13,DAAM2,PMEPA1,URM1,CAMK1G,NUP214" Drug 1600_UP Nicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "NDRG2,ANK2,APOC1,APP,ATM,EIF4G3,ATP2B1,RIPK1,KRIT1,CD86,PREPL,PPP1R16B,ARHGAP32,NR1D2,DTNA,EGR3,KCTD3,DENND4A,F3,ACSL4,KIAA1109,SEC23B,SMC2,SRCAP,COPS8,PDE3B,PLCD1,PPP2R5C,MSANTD2,RPRD1A,ATXN7,CHD9,RAB3GAP1,MAPKBP1,BEX1,SPART,THSD1,EPB41L3,NXT2,GSE1,CBX5,NPL,FLRT2,EPM2A" Drug 4098_DN Furazolidone [67-45-8]; Down 200; 17.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "NME5,APOC1,CDK10,SEMA4G,ARRB2,SYNJ1,ARHGEF1,FOXN3,PLEKHB1,HOMER3,CSF1,CNIH3,KIAA0753,PLEKHO1,ZNF589,PDLIM5,ZNF44,SYT17,C1QL1,BACH2,IL6ST,MBD1,MX1,NUMA1,PAK3,PDE1C,PDE4D,PLPPR1,BEND5,MYH14,RPS20,DOCK10,SNCA,SYT11,ASTN2,RPGRIP1L,PCDHGA10,GPR161,R3HDM1,UBTF,XRCC4,ZNF74,WNK1,MAP3K12" Drug 2870_UP Gliclazide [21187-98-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ABHD6,ADCY6,AP2A2,OGT,APAF1,APBA2,FAM131A,ALDH4A1,ATP2B2,CALB1,CALB2,ADGRG1,TAOK2,FAM149A,VCAN,CTIF,ATN1,ERCC2,KHDRBS3,FYB1,ATP8A2,IGF1,ITPKA,PCBP3,PFKFB2,PACSIN1,MASP1,FAT4,EMID1,CPEB3,DOCK10,SHANK2,WDTC1,DOK5,SP4,IQSEC2,PSD3,CRTC1,SLC44A1,TPM3,UCHL1,FLRT2,KCNAB1,ADAMTSL3" Drug 1945_DN Azathioprine [446-86-6]; Down 200; 14.4uM; PC3; HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADD1,BRAP,AK2,TAOK2,EPS15L1,ARHGEF6,PPP6R2,C2CD2L,LYPD1,DLG3,DNM1,RCAN1,DTNA,ATP2C1,SEPT9,OS9,GRIK5,KCNMA1,IPO5,MARK3,NRGN,PALM,PRKAB2,CNNM2,CEP97,FAM102A,PEX26,SLC11A1,ARFGAP1,FNBP1,NMNAT2,NCDN,VAMP1,IQCE,TCF4,DMXL2,TCF7,ZEB1,TRIM2,PSD3,OBSL1,SPX,KLC2,SPHK2" Drug 6268_DN Methazolamide [554-57-4]; Down 200; 17uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "MTMR9,ATP6V0A1,OSGIN2,NMT2,CHD1L,NCOR1,GIT2,FBXL5,RHOBTB1,PARD6A,RCAN1,DTNA,RBM12,F8,DIDO1,BTN2A1,MAP4K5,ARHGAP19,IPO5,LSS,MEIS1,NACA,ODF2,PLXNB1,PMS2,RETREG2,RAP1GAP,RXRA,AMBRA1,SMARCC2,RCOR3,SP2,PRRC2C,ANKRD12,EXOC7,TCF7L2,WDR7,TRIO,VAV1,CLDND1,ZNF23,MPPE1,PHTF2,NUP214" Drug 7380_DN Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "KIDINS220,BIN1,APBB2,APLP1,CDK10,MARK4,SYNJ2,MYRF,KYAT1,ARHGEF1,QKI,SLITRK5,RHOBTB1,DLG3,CDON,EN2,F3,SCML2,SCARA3,PDLIM5,ATP2C1,TRAF3IP2,GAD1,CRCP,GUCY1B1,MUM1,MBD1,NUMA1,PAK3,PEX5,SUGCT,ZNF671,NCBP3,SBF1,KIF16B,AMBRA1,SHANK2,ZBTB43,GSE1,KIAA0930,ZNF34,ZBTB14,TRIM9,PLSCR4" Drug 5888_DN Mesalamine [89-57-6]; Down 200; 26.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ACTN1,ADD1,AMT,APLP1,PPFIA3,APP,SLC4A4,C5,CLU,CHD1L,CNTNAP2,KIAA0513,PARD6A,SGK2,SIDT2,EFNA3,IRAK4,MRNIP,FGFR1,SEMA4D,GAD1,RASSF8,MBD1,MKLN1,MPP2,TAGLN3,PCDH9,PTN,PID1,KHDRBS2,SBF1,SH3BP2,AMBRA1,TMCC1,ZBTB43,GSE1,VPS13A,IQCE,CBX5,CABIN1,WBP2,PLPPR2,NAV3,MPPE1" Drug 3749_DN Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AMPD3,APC,APP,ALDH7A1,NRP2,ST3GAL5,ASIC3,ARMC8,SLITRK5,ZNF337,DAPK3,LRRC23,ANKMY1,ELOVL5,IL11RA,INPP5B,ITPKA,MAPT,CNOT4,SLC11A2,ODF2,RETREG1,PPARA,TCP11L1,ATXN7,SCN8A,ST6GAL1,DZIP1,FAM214B,SMARCD3,ARHGAP26,ATP10B,CAMSAP2,KIAA1107,SMG6,RPGRIP1L,TNS2,DNAH7,THRA,TNS1,VLDLR,SCG2,WIPF2,DPF3" Drug 1991_UP Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "PLA2G6,APAF1,ASPH,BCL7A,NRP2,MTMR3,CA12,CNOT8,SH2B1,G3BP2,DPH1,TOM1,EFNB3,KCTD3,MRNIP,ZNF589,FHL1,ATP2C1,ARFIP1,GNG3,SPACA9,KLF12,VWA5A,MYO7A,FXYD7,NOS1,PALM,PDE1C,NLE1,RAP1GAP,TCP11L1,GALNT10,EMC1,SPART,SRPK2,MAPK8IP3,PHLDB1,PDLIM2,TCF4,DMXL2,AHCYL2,SMUG1,PDIA2,HPS4" Drug 1911_DN Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "APAF1,MARK4,ATP2B1,BACH1,FUBP1,PLAA,ELAVL2,EZH1,KIAA1109,CAP2,TRMO,ATP2C1,OGA,TRAF3IP2,NCKAP1,WASF3,NUDT21,RNFT2,HMGCR,HNMT,LAMP2,NEK1,NOVA1,SETD4,PTK2,RDX,REV3L,RFX5,RNF220,ATXN2,TRA2B,SH3BP2,FAM102A,SH3GL3,FBXO11,RCOR3,POGZ,FAM168A,WASHC4,CBX5,DNAJC12,SPHK2,PRDM2,EVI5" Drug 3444_UP Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "CDK10,ALDH4A1,ATP2B3,CACNA2D2,RCBTB2,ASIC3,SLC4A8,SH2B1,AATK,CSF1R,ARHGEF4,CTIF,C2CD2L,GNE,CDKL3,FHL1,EFCAB2,MSL3,MATK,TM6SF1,MEF2C,MGAT3,ADAM22,NEUROD1,SERPINE2,SMOX,TNPO2,ZDHHC14,TCP11L1,RASA3,BTBD7,KDM4B,SOX2,ZHX3,SPTAN1,STX1A,EXOC7,SMG6,PSD3,SLC44A1,FLRT1,ZIC3,REEP1,PARP11" Drug 6477_DN Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "APP,ATM,LDLRAD4,KRIT1,RABGAP1L,OPTN,EFNB3,PLXNC1,EML1,PLEKHO1,EPB41L2,CSPG5,GAD1,SYT17,MSL3,NUDT21,BTN2A1,IGSF1,IPO5,VWA5A,MAPT,LYRM9,NF1,NFYA,P2RY1,PPP3CC,WDR25,ELOVL2,PTN,ZSCAN32,TMEM231,RAD52,KHDRBS2,RGS3,SAFB,FAM214B,TROVE2,TTBK2,MTCL1,RPGRIP1L,WDR7,TK2,CLDND1,SEMA3B" Drug 5878_DN Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ABHD6,NDRG3,ADD1,AMPD2,ANK3,APP,ASPH,STX16,ALDH7A1,MPDZ,CA12,ZFYVE9,CNTNAP2,DCAF8,DBT,B3GAT3,DLG3,DPH1,RCAN1,SGK2,MRNIP,STX2,ETV1,CGREF1,CSPG5,TRAF3IP2,PCLO,MAP4K5,RASSF8,AGFG1,KCNMA1,MMP16,MPP2,TAGLN3,PDE4D,SSH1,PIK3R1,POLG,GTDC1,PAQR6,SEC14L1,SH3BGR,ROBO3,VPS35L" Drug 1425_UP Ornidazole [16773-42-5]; Up 200; 18.2uM; HL60; HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "C1QTNF1,CDC42BPA,MARK4,SLC4A4,CADM3,BMP7,ST3GAL5,CAST,INA,CHRNB2,ZNF337,CTIF,DDX46,ATN1,FEM1B,IRAK4,EPB41L2,KIAA1109,FHL1,C1orf61,CAMKK2,GAA,GJB1,TXNL4A,GRIA4,KHK,NACA,NTRK3,CAMKV,CCSER2,EPB41L4B,GON4L,RAD51D,RLBP1,NEK11,TCP11L1,SLC15A2,ELMO2,MAPKBP1,FNBP1,SYN2,CAMSAP2,RBFOX2,TRIM9" Drug 1292_DN Clebopride maleate [84370-95-6]; Down 200; 8.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "GRAMD1B,PPFIA4,ARNTL,CDK13,ZBTB10,ATM,STX16,BCL7A,SCAPER,CBR1,HOMER3,HINFP,DOCK4,ZNF337,SMG7,EEF1A2,GPHN,POLR1B,ARFIP1,HTATSF1,GNAS,CACFD1,AGBL5,ARHGAP12,NF1,ODF2,GPSM2,LRP12,RAD52,BSDC1,TRIM68,SH3BP2,SIRT2,ZCCHC24,COLGALT2,SS18,NXT2,AHCYL2,TLR4,PARD3,NR2C2,XRCC4,FTSJ1,MPPE1" Drug 1319_UP Cefotetan [69712-56-7]; Up 200; 7uM; HL60; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "RALGAPA1,ABAT,BRAP,APBB2,APC,SYNJ1,SCAPER,C5,MAP7,INA,SCARB1,DSCAM,RCAN1,DTNA,ST8SIA3,EDNRB,ZNF589,CELF1,GART,USP19,GLUL,GRM1,SOX21,LIG4,ZNF862,NPPA,PMP22,PMS2,MAPK8,RELN,CNTLN,RASA3,FNDC3A,PREX2,MYH15,DOK5,IZUMO4,EXOC7,KIAA1107,PIK3R5,VAV2,LMF1,ZNF32,TRIM9" Drug 5264_UP Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "KIDINS220,KALRN,NEURL1,CDH10,CDO1,SOCS6,CHRNB2,CNTN1,RIMS2,BRINP1,NTM,TMCC2,EFNB3,ELAVL3,FABP7,OLFM1,FOXG1,C1orf61,FLNC,GABRA2,GABRG2,GRIK4,GRM1,IRF8,SHISAL1,TJAP1,MSI1,ADAM22,PCBP3,POLG,EMID1,SLC1A2,SLC2A5,SNAP25,ATP10B,DMXL2,ZEB1,PCDHGB6,SZT2,HEY2,TRH,UBE3A,WIPF1,MVB12B" Drug 122_DN alpha-estradiol; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ASIC1,MTUS1,APP,CDK13,ALDH4A1,CAST,RUNX1T1,LRBA,NIPBL,RNF14,AATK,FBXL5,DNAJB6,EPB41L2,CAMKK2,AHCYL1,GLS,ZNF638,ITIH2,MAP4,AFF1,MXI1,NFE2L2,GPSM2,EXOSC10,RETREG2,MED1,PRPH,PTK2,SPDL1,QDPR,RAD51D,ATXN2,ITSN1,ELMO2,FNBP1,MYCBP2,ST5,TAC3,WASHC4,NSD1,UBE3A,WNK1,VPS35L" Drug 1813_DN Triflupromazine hydrochloride [1098-60-8]; Down 200; 10.2uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "C1QTNF1,APBB1,APP,CDK10,PLEKHB1,LHX2,ARHGEF6,IQCK,SLC4A7,CSF1,IRAK4,SCML2,TESK2,FGFR1,CGREF1,SRCAP,GLRB,GPER1,GUCY1B1,MPP2,ZNF862,PPP3CC,SAMD9,ARID4A,NUDT11,ASAP3,AMBRA1,LIMS2,FAM214B,FNBP1,RGL1,VAMP1,ARHGEF9,DNMBP,EHBP1,NSD1,ATP13A2,TRPC1,KLC2,ZNF32,TFIP11,MAP3K12,ST7,SMIM8" Drug 2640_UP Ketoconazole [65277-42-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "NME5,ALK,MRTFA,BIN1,ASPH,ATP6V0A1,ADAM23,CACNA1G,LDLRAD4,STOML1,DNAJB5,CTNND2,EXOG,DTNA,C3orf18,DMTN,TUBB4A,KHDRBS3,SEPT9,IL6R,INPP1,KCNJ3,VWA5A,MID1,AFDN,MMP16,NDUFA5,NEK1,NF1,NOS1,PACSIN1,ELOVL2,RFX2,RGS12,ASAP3,SOX10,SPTAN1,DDN,THSD1,SYT5,SMG6,THBS4,HEY2,VAV2" Drug 3891_DN Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AK2,APBB2,CACNB2,HIP1R,WHRN,ARHGEF4,CTIF,PLXNC1,EIF4G2,LRRC23,ERCC2,GCNT2,SRCAP,POLL,GNG4,PCLO,IL6ST,KCNF1,MAP2,MID1,MMP17,BCO1,CNOT4,NPPA,NPTX1,PLCD1,LRP12,MAPK10,FAM120C,ZSCAN2,RAB3A,RAB3IL1,FAM184A,RGS12,SBF1,PPP1R9A,ANKRD6,LHPP,RPGRIP1L,SLC44A1,HEY1,TMOD1,PLPPR2,WNK1" Drug 1889_DN Dibucaine [85-79-0]; Down 200; 11.6uM; PC3; HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADD1,AP1B1,BIN1,APC,SHROOM2,PTBP2,KRIT1,SRSF11,CHRNB2,MED12,DNAJB6,ANKRD46,ELAVL2,ACSL4,FGFR1,SEC23B,OGA,NCKAP1,GART,TXNL4A,CRCP,GLS,NUDT21,NAP1L1,OPA1,SSH1,LRP12,TMEM231,RAP1GAP,RBBP6,MRPS18A,FAM102A,SH3GL3,SLC2A5,ZNF430,SLC22A4,EPB41L3,LARP4,TCF7L2,WDR7,ZNF106,CBX5,UBTF,ZNF189" Drug 2879_DN Ethamivan [304-84-7]; Down 200; 18uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "NDRG2,ALCAM,AMPD3,ARHGDIG,ATP6V0A1,SYNJ2,ARHGEF1,RCBTB2,ASIC3,CHM,TAOK2,ABI3BP,NECTIN3,FAM169A,NOS1AP,DOCK4,RABGAP1L,KBTBD11,EXOG,SORBS3,LRRC23,CDKL3,CAMSAP1,HBS1L,ERAP1,DISC1,CLASRP,TJAP1,IGSF1,KITLG,NEK1,NRGN,PLPPR1,RAB3A,RAD52,RGS10,RYR1,SPTAN1,IQCE,CRTC1,TK2,TMOD1,REEP1,EPM2A" Drug 7133_DN Isopropamide iodide [71-81-8]; Down 200; 8.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "BRAP,CDK10,ASPH,CDK5R1,FOXN3,B4GALT6,CNOT8,KIAA1549L,FADS2,TENM4,SDC3,ZNF337,SPATA2,RHOBTB1,SUGP2,EML1,ZNF589,CAMSAP1,GAA,DENND2A,HBS1L,CRCP,GLS,GOLGB1,MAN1B1,SMAD1,MYO6,NUCB1,PBX1,MAPK3,SBF1,ITSN1,FAM102A,SEPT8,TTBK2,ARHGEF9,VPS13A,TK2,SSBP2,HIRA,KLC2,XRCC4,PHTF2,ACTR3B" Drug 2855_DN (R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "APOC1,CDK10,ARHGDIG,GYG2,TAOK2,QKI,MFAP3L,EIF4G2,TNK2,EPB41L1,ZNF589,ANKFY1,GPR153,ERAP1,GPER1,NR3C1,INPP5B,ITPKB,GIT1,FAM184A,RGS10,ZNF821,SH3BP2,SMTN,SLC22A4,SMARCD3,ZCCHC24,EMC1,TROVE2,CAMTA2,ST5,ARC,TACC1,IQCE,TNS2,CHST8,PLPPR2,MICAL1,WIPF1,SYNC,UPF3A,SEMA3B,SMIM8,SSPN" Drug 5817_DN Cinnarizine [298-57-7]; Down 200; 10.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "KIDINS220,MTUS1,ASPH,ATM,CFLAR,SOCS6,WHRN,BAG4,SDC3,FBXL5,KLHL3,FEM1B,LPAR6,SORBS3,EPB41L1,ERBB2,FAM49B,TRAF3IP2,DENND2A,PRRC2B,KIF3A,KLF12,IFI16,DIPK1A,MEF2C,MEIS1,OCRL,PBX1,CDK14,CCSER2,CNNM2,RAB5B,RNF220,KIRREL1,TCP11L1,UNC5B,ZBTB43,WSCD1,SLC35G2,ATP13A2,RBFOX2,HPS4,MPPE1,ST7" Drug 4197_DN "Canavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "PLA2G6,MRTFA,APP,ARRB2,MARK4,NRXN3,CPS1,CREM,RGS6,DCAF8,MBNL2,SORBS3,EN2,EPB41L1,ZNF589,TRAF3IP2,LPAR4,MBD1,NEK1,PBX1,PDE4D,RETREG1,TMEM231,PID1,RAD52,ZCWPW1,SUGCT,MAP6D1,ATXN7,FRMPD1,AMBRA1,PEX26,KDM4B,SOX2,DDN,VAMP1,ARHGEF9,GPR161,TIMP4,PARD3,ZMYND8,SSBP2,ZNF45,AAAS" Drug 3793_DN Quinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ADCY2,ALAD,RASL11B,ALDH7A1,MYRF,CANX,CACNA2D2,CLCN4,HAPLN1,CRY2,CSF1,PHF14,RIMS2,ARMCX2,DTNA,SCML2,FGF1,CGREF1,KCNMB4,EML4,CACFD1,RASSF8,ATXN2L,SCIN,ITGA7,MDM4,CNOT4,PENK,NLE1,EPN1,DOCK10,NLGN1,SLC1A7,PREX2,BTBD7,TSNAXIP1,COBL,KIAA1107,TCF4,TIAM1,ZNF24,PRDM2,EVI5,PHTF2" Drug 5389_UP Ganciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AP2A2,MRTFA,APBA2,FAM131A,PLA2G4C,BACH1,NEURL1,CDH18,CLGN,IFFO1,AKAP12,DMPK,DTNA,ELAVL2,EN2,FYB1,GATM,GLYR1,PRRC2B,ADAMTS13,NR3C1,GRM7,GUCY1A2,HNMT,TJAP1,JAK2,MAP4,PDE3B,PPP5C,CEP41,TCP11L1,SLC1A2,SHANK2,CXXC4,KDM4B,SYP,SYT5,RPGRIP1L,DOCK9,TUBB1,UGT8,LAT2,WNK1,SENP7" Drug 4526_DN "Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A" Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "ASPHD1,MTUS1,ALAD,BIN1,CDK10,ARRB2,CBFA2T2,TPP1,HOMER3,CREB5,PPP6R2,TBC1D5,RUSC2,DNM2,MRNIP,COQ7,SPEG,ZNF589,FGFR1,TRMO,INPP5K,USP19,ARHGAP19,MAN2A2,MMP16,MT1M,MYO6,PPP5C,BCAS3,GON4L,FBXW7,SFPQ,SLC20A2,KDM4C,ZBTB43,CAMTA2,MAPK8IP3,TRIM2,ZKSCAN5,UBTF,NSD2,HPS4,WIPF2,NUP214" Drug 6337_DN Doxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "AP1B1,CLU,QKI,NIPBL,SIPA1L1,DBN1,PARD6A,TNK2,EFEMP1,FCGRT,BAIAP2,TRMO,TRAF3IP2,DENND2A,INPP5K,GART,GPM6B,GSN,MAN1B1,KIF2A,KIF5C,MAN2A2,NASP,PTPA,TMEM104,PTHLH,MAPK12,SUPT20H,SH3BGR,PEX26,SLC14A1,SMARCA4,SMARCC2,BEX1,ST5,MAPK8IP3,ARHGEF9,VPS13A,AHCYL2,CABIN1,ZNF384,UBTF,WIPF1,WIPF2" Drug 2960_DN Phensuximide [86-34-0]; Down 200; 21.2uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "C1QTNF3,BIN1,PPFIA4,SLC4A4,SYNJ1,SYNJ2,CAMK2G,SMARCAL1,CST3,CX3CR1,SGSM2,DTNA,FEM1B,EIF4G2,CD320,FGFR1,PRKAG2,ZMYND11,ADAM28,CRCP,GLS,GPR22,GSN,IL11RA,VWA5A,AFF1,MX1,CNOT4,ODF2,TMEM104,PTAFR,RAD52,ZNF493,RGS10,MAPKBP1,TNIK,TCF7,RBFOX2,TPM3,PLPPR2,TFIP11,PRDM2,PARP11,AAAS" Drug 1527_UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "SRPX,MRTFA,SEMA7A,APBA2,APBB2,ARRB1,BRINP2,RASL11B,ALDH7A1,CAMK2B,CACNA2D2,TAOK2,HOMER3,SLC4A7,GIT2,EFNB3,EIF4G2,SORBS3,SPEG,BAIAP2,CAMSAP1,TXNL4A,GLS,POLL,BCO1,NACA,NF1,KCNK10,PRKCB,PRPH,SEC61A2,CNKSR2,SYBU,ERC1,THSD1,INKA2,STX1A,TCF7L2,RUNDC3B,PDIA2,ZBTB14,MPPE1,PAK5,KAT6A" Drug 5067_DN Tridihexethyl chloride; Down 200; 11.4uM; PC3; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.97E-02 5.66E-01 44 199 "MTUS1,EPB41L5,SLC4A4,CDK5R1,REPS2,CLU,ENTPD4,CSF1R,VCAN,DLG3,EFNA3,ZNF589,SCARA3,FOXG1,GAD1,C1QL1,GPM6B,TDRKH,KIF3A,L1CAM,MIA2,NUMA1,PAK3,PFKFB2,SERPINI1,PIK3R1,SMIM7,PLXNB1,PTHLH,RAB3A,BSDC1,GAL3ST4,DZIP1,FAM214B,ZNF667,LIMCH1,WDTC1,ASTN2,TPM2,TRIO,CADM1,VIPR2,NDRG4,SPHK2" Drug 6339_UP Pyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; PC3; HT_HG-U133A Broad Institute CMAP Up 1.07E-02 1.00E+00 4.98E-02 5.66E-01 41 183 "C1QTNF1,ATP2B2,CACNA1I,CACNA2D1,HAP1,CARS,ARHGEF2,ZMYM4,SULT4A1,CREM,ENTPD4,AATK,CTH,FGFR1,PRELID3A,ZNF44,TRAF3IP2,MTHFD2,ALDH1L1,GRB10,KLF12,IL6ST,IL12A,ITPKA,VWA5A,MIA2,NCAM2,NOVA2,PAK3,PDE4D,CDIP1,PTPRN2,GAL3ST4,ZNF821,ATP10B,ZNF34,HEY1,LMF1,LAT2,SEMA3B,SLC17A7" Drug 2696_DN LY 294002; Down 200; 10uM; HL60; HT_HG-U133A Broad Institute CMAP Down 1.07E-02 1.00E+00 4.98E-02 5.66E-01 41 183 "MTUS1,ANK2,MAP7,CBS,CLCN4,QKI,HOMER3,ARHGEF10,SLITRK5,CTH,CX3CR1,DBN1,RHOBTB1,KBTBD11,FRY,RASGRP2,SYNCRIP,CAMKK2,SEPT9,GRB10,IRF8,IFI16,TM6SF1,MGAT3,DEF8,RNH1,LGR4,ST6GAL1,SLC2A5,ZHX3,TSPYL2,DDN,COLGALT2,GSE1,KAZN,CAMSAP2,KIAA0930,THBS4,TNS1,HPS4,NAV3" Drug CID000057112 lifibrol Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "SCARB1,FDFT1,MTTP,GPR85,PPARA,SLC12A4,NETO1" Drug ctd:C049109 zolpidem CTD 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "GABRA1,GABRA4,GABRB1,GABRB3,GABRG2,SST,SSTR2" Drug CID000024591 BiCl3 Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "ALK,BSN,CBS,CNOT8,GPR162,NBL1,NEUROD1" Drug DB00909 Zonisamide Drug Bank 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "CACNA1I,CACNA1G,CA4,CA12,MAOB,SCN2A,SCN3A" Drug CID000108055 alpha-methylphenylalanine Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "AMT,GAL3ST1,HMGCR,NEFM,PAH,SHMT2,TUBA1A" Drug CID000114771 dichlorobenzamil Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "CACNA2D1,INA,FER,GAP43,HCN1,SLC8A1,TACR1" Drug CID000009262 "1,3,5-triazine" Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "APPL1,BVES,MATN3,PMP2,RDX,PBRM1,SOX10" Drug CID000003851 "L-703, 606 oxalate" Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "EDN1,B3GAT1,GRIK1,SST,TAC1,TAC3,TACR1" Drug CID000017248 tetrapentylammonium Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "KCNA1,KCNA2,KCNA4,KCNA6,KCNC1,KCNC2,KCNMA1" Drug CID000155806 8 mm x Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "ALDH7A1,KRIT1,PDE1C,PDE2A,PDE4B,PDE4D,PDE1B" Drug CID005702627 dehydrophenylalanine Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "BOC,DMPK,FGFR1,B3GAT1,MTR,TAC1,TACR1" Drug CID005961627 PPNDS Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "GRIA1,GRIA2,GRIA4,GRM3,P2RY13,P2RY1,P2RY12" Drug CID000131092 HDMA Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "ATP1A1,ATP1A2,ATP1A3,ATP1B3,FGF1,FGFR1,UCHL1" Drug CID000170472 urethane dimethacrylate Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "BLM,CNOT8,DBI,F8,MAG,CLDN11,NLRP3" Drug CID003034917 Ct-15 Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "APP,SIRPA,ENO2,FER,GSN,PRKCB,SLC6A8" Drug CID000447153 "2,3-difluorobenzyl alcohol" Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "ABR,DBF4,GRM1,GRM2,GRM5,GRM8,ADHFE1" Drug CID000008631 di-u Stitch 1.07E-02 1.00E+00 4.98E-02 5.66E-01 7 17 "EDNRA,CIT,IGFBP1,RAB3IL1,RNASE1,PEG10,CYB561A3" Disease C0036341 Schizophrenia DisGeNET Curated 1.69E-36 2.08E-32 2.08E-32 2.08E-31 457 1561 "SERPINA3,DGCR6,ABCF1,SYN3,ACHE,CSMD2,ADCYAP1R1,BRAP,SLC12A5,ADORA1,ADORA2A,ADRA1D,KIDINS220,PLA2G6,C1QTNF3,ALK,MRTFA,ANK3,APBA2,APC,DGKZ,DDO,APP,AQP4,ARRB2,PLA2G4C,ASCL1,ASPA,ASTN1,ATM,ATP2A2,ALDH7A1,BCHE,RGS9,BID,CDK5R1,ARHGEF7,CACNA1B,CACNA1D,DDR1,CACNB2,CALB1,CALB2,CALM1,KALRN,CAMK2B,SLC25A14,MAP7,CBS,KYAT1,CCK,KRIT1,P2RX6,ARHGEF2,SEPT7,CDC42,DCLK1,ARHGAP33,MAGI1,DLGAP2,DLGAP1,NUMBL,CHGA,CHGB,CHRM1,CHRM4,CHRNA4,CHRNB2,NDST3,KMT2C,DLGAP3,NRXN3,PLAA,NRXN1,NRXN2,CLU,FADS2,QKI,SULT4A1,CNR1,PICK1,SLC25A27,AKAP5,TBPL1,CP,CLOCK,CREM,ENTPD4,CRHBP,CRMP1,CRY2,SLC32A1,TENM4,CSF2RA,FEZ1,CSNK1E,NCAN,CNTNAP2,CALY,CTNND2,RIMS2,NOS1AP,DOCK4,HDAC9,ARHGAP32,HDAC4,KIAA0513,RIMS3,DBI,DBN1,DCC,ZNF804A,ZEB2,CNIH3,KIAA0319,MAGI2,SNAP91,SV2A,SRGAP3,ARNT2,DLG2,DLG3,DLG4,DLX1,GRIN3A,DMD,DNM1,MED12,CALN1,DNM2,SHANK1,SLC12A6,DPYSL2,DRD1,DRP2,DTNB,USH1C,EDNRA,EEF1A2,SEMA3D,TMTC1,EBI3,EGFR,EGR3,EIF5,ELAVL2,EMX2,EN2,OLIG2,ENO2,EPHB1,ERBB4,RTN3,SIRPB1,NRN1,FABP7,CACNG2,ACSL4,PTK2B,DLC1,KAT8,PPP1R1B,FGFR1,SUCO,AGAP3,FOLH1,PDLIM5,NPTN,CAMKK2,GPR153,CSPG5,B3GAT1,NRG3,FYN,DKK3,MEGF10,GAA,GABBR1,GABRA1,GABRA4,GABRA5,CHL1,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,RAPGEF6,GAP43,DISC1,ATP8A2,CPLX2,CPLX1,GFAP,GFRA1,GFRA2,PCDH17,GGTA1P,GHR,PPARGC1A,NTNG2,HPGDS,GLS,GLUL,KDM2B,GNAL,GNAO1,GNAS,GPM6A,MCHR1,PCLO,STMN2,GRB10,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,GRIN2D,NR3C1,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,GSN,PTPN5,GSTT2,PADI2,HRH3,KLF12,ELOVL5,SYNPO,HNMT,HP,HSPA1L,HTR2A,HTR5A,IGF1,IL6R,IL12A,LRRTM1,ITGAM,SLC35G1,KCNB1,KCNH1,KCNH2,CLVS2,KCNJ3,KCNJ10,KCNN3,KCNQ2,KCNQ3,KIF2A,KIF5A,IPO5,LAMA2,LIFR,LIG4,LSAMP,MAG,MAOB,MAP2,MAP6,MARK1,MBNL1,MBP,LRP1B,MOBP,MOG,MPP2,MSRA,CTNNA3,MTTP,MTR,MDGA1,MYO7A,FXYD6,NCAM1,NDP,NEFM,NEUROD1,NOS1,NPY,NPTX1,NRCAM,NRGN,NTRK2,NTRK3,OPA1,OPCML,CLDN11,OXTR,P2RX7,P2RY1,PAH,TREM2,PAK3,PAX6,PCDH8,PDE4A,PDE4B,PDE4D,PDYN,GPR85,ZDHHC8,ABCB1,SERPINI1,NALCN,PIK3CD,FTO,FXYD1,PLP1,PLXNB3,PMP2,PMP22,PSAT1,MAGEL2,RETREG2,POU3F2,PPARA,PPP2R2B,PPP3CB,PPP3CC,MAPK3,MAPK8,PRODH,RELN,CNNM2,NDUFS7,PSD,LAMA1,BDNF-AS,EML5,PTPRZ1,RASGRF1,RGS4,RGS10,RGS12,RIT2,PBRM1,ALG9,CCDC25,LRRK2,LGR4,SYNDIG1,S100B,SAFB,ATXN2,SCN2A,SOX6,PPP1R9A,NTNG1,AMBRA1,BCAN,NLGN1,SLC1A2,ZNF365,SLC1A3,SLC1A6,SLC6A1,PKNOX2,SLC6A9,SLC6A11,SEPHS1,SHANK2,SLC12A2,TET1,SNAP25,SNCB,MYO16,MYT1L,TNIK,SOX5,SOX10,SP4,NPAS3,NFASC,LMO3,SST,MAPK8IP3,NEK4,STX1A,STXBP1,SYT11,MLC1,VAMP1,PLCB1,SYN1,ARC,SYN2,SYP,ASTN2,TAC1,TACR1,TAL1,WWC1,ACSL6,TCF4,TCF7L2,PSD3,TF,DICER1,SIRT1,ZFPM2,TIMP4,TLR4,NR2E1,DAAM2,TNFRSF1B,CSMD1,CABIN1,RASD2,NPL,PDSS1,AMACR,TSC1,TSC2,UGT8,VGF,VIPR2,VLDLR,BEST1,VSNL1,ETNPPL,XRCC4,ZIC2,ZNF74,SLC30A3,LRP8,SLC38A1,LMAN2L,HPS4,PCDH15,NAV2,SLC17A7,WNK3,SLC17A6,NELFE,PLSCR4,FZD3,RTN4,HNRNPA3,NUP214,ADAMTSL3,ADAMTS10,NETO1,ST8SIA2" Disease C3714756 Intellectual Disability DisGeNET Curated 1.97E-24 2.43E-20 9.83E-21 9.82E-20 326 1131 "DGCR6,ARID1A,PTCHD1,ADRB2,NLGN4X,PCDH19,NR0B1,CC2D2A,PLA2G6,AMH,AMT,CDC42BPA,ANK1,ANK3,KCNAB2,APC,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,CDK5R1,SYNJ1,SCAPER,CACNA1G,WASF1,CA4,CA8,CACNA1D,CACNA2D1,CAMK2A,RUNX1T1,CBS,AIFM1,CD38,AP4M1,ARHGEF2,CDC42,LARGE1,NOG,ADGRG1,NRXN3,CLCN4,NRXN1,ABCG2,NIPBL,ARHGEF6,CPS1,SH2B1,RGS6,CNTNAP2,CTNND2,RIMS2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBN1,DBT,DNAJC6,ZEB2,ZBTB24,SACS,SRGAP3,DLG3,DLX1,RAB39B,DMD,DNM1,MED12,TRAPPC9,SHANK1,SLC12A6,DPH1,DPP6,DSCAM,RCAN1,DYRK1A,USH1C,WDPCP,EEF1A2,FRY,AASS,BSCL2,ELN,EMX2,VPS13B,EPS8,ERCC2,APC2,EYA1,WAC,ACSL4,TUBB3,FKTN,ZNF589,FGF13,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,COQ5,POMT1,TBR1,AP4B1,STAG2,GABRA1,CHL1,GABRB3,GAD1,ZMYND11,DISC1,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,KIRREL3,NTNG2,GK,RNPS1,GLDC,GLRB,GNAS,GPT2,CNDP1,GPD2,NUDT21,GRIA2,GRIK2,GRIK4,GRIN1,GRM1,GRM7,IL1RAPL1,MFSD2A,HBA1,MAN1B1,HNMT,HNRNPK,ZDHHC15,AGFG1,ATCAY,IDH3B,IGF1,TMEM240,IL12A,SLC6A17,ZNF385B,ITGA7,KCNA2,KCNH1,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF5C,L1CAM,LAMA2,LAMP2,LIG4,MAOB,MAPT,MEF2C,MEIS2,MID1,MTR,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,NF1,NFIX,NRCAM,OCRL,CHAMP1,OMG,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,NLGN3,NALCN,PLP1,MAGEL2,NXPH1,POU3F2,PPP2R2B,PTPA,KANSL1,PRKCG,MAPK10,PRODH,MASP1,CNNM2,LAMA1,GON4L,PIGG,PTCH1,PEX2,PEX5,QDPR,RALGDS,RBBP8,RET,PRRT2,RGR,UBR7,RGS7,KIF7,RLBP1,SETD5,TMLHE,CARF,ROM1,ELP2,RPE65,ZC3H14,LGR4,CLIP1,SALL1,ATXN1,SCN2A,SCN3A,SCN8A,FOXRED1,ARX,NTNG1,CNKSR2,ST3GAL3,SLC6A7,SLC6A8,RAB3GAP1,SHANK2,SMARCA4,CDK5RAP2,SMARCE1,SNAP25,MBD5,SNRPN,MYO16,MYT1L,SOX3,SOX5,SOX10,SOX11,EMC1,ZNF423,ARHGAP26,SPTAN1,IQSEC2,NPAS3,POGZ,ZC4H2,KANK1,STXBP1,ABCC8,ARHGEF9,SYP,SYT1,DDHD2,CAMTA1,TAL1,TCF4,DMXL2,SATB2,RPGRIP1L,WASHC4,SZT2,NSD1,DICER1,CRB1,AP4E1,THRA,ASXL3,KAT6B,TNR,RBFOX2,TRH,TRIO,TRPS1,TSC1,TSC2,TUB,HIRA,HEPACAM,CADM1,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,FMN2,ZBTB16,FTSJ1,LMAN2L,TUBA1A,NELFE,DOCK8,KAT6A,NUP214,JMJD1C,NLRP3,SNX14,AAAS,FXR1,SLC4A10,GAN" Disease C0014544 Epilepsy DisGeNET Curated 2.39E-24 2.95E-20 9.83E-21 9.82E-20 288 962 "ABAT,ACADM,ARID1A,SLC12A5,ADRA1D,PCDH19,PLA2G6,SPARCL1,SEMA6A,PCDH10,KCNT1,AMPD2,AMT,ANK2,APBA2,KCNAB2,APP,AQP4,CASK,ASCL1,ASPA,ALDH4A1,ATM,ATP1A2,ATP1A3,ATP2A2,ADAM23,MPDZ,HCN2,BCS1L,NRP2,CFLAR,SYNJ1,ST3GAL5,SGCE,NIPA1,CA8,CACNA1A,CACNA2D1,CACNB4,CALM1,CAMK2D,CBS,KRIT1,AP4M1,LGI1,LARGE1,ADGRG1,CHRM1,CHRNA4,CHRNB2,SLIT2,CLCN4,NRXN1,CLU,TPP1,ABCG2,NIPBL,CNN3,CNR1,RTTN,SLC35F1,CPS1,PREPL,SH2B1,SLC32A1,CNTNAP2,RUBCN,HDAC9,HDAC4,DBT,DNAJC6,ZNF804A,ZEB2,MAGI2,SV2A,ARNT2,DLG4,DLX1,RAB39B,DMD,DNM1,MED12,SLC12A6,GNE,DYRK1A,ABCC5,EEF1A2,EGR3,AASS,TNK2,BSCL2,ELN,EML1,EMX2,SEZ6,GPHN,ERBB4,ERCC2,ADGRV1,FABP7,CACNG2,FKTN,STRADA,FGF13,FGFR1,FGFR3,FOXG1,POMT1,STAMBP,TBR1,AP4B1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRB3,GABRG2,GAD1,GALC,ATP8A2,CPLX1,GCK,TUBGCP4,TUBA8,GFAP,MMADHC,GK,GLDC,GLI2,GLUL,GNAO1,GNAS,PCLO,GRIA1,GRIA2,GRIK1,GRIK2,GRIN1,GRIN2C,GRM1,GRM2,GRM3,GRM7,GRM8,PTPN5,MAN1B1,HMGB1,HP,HTR2A,KCNA1,KCNA2,KCNB1,KCNC1,KCND2,KCNH1,KCNH2,KCNJ10,KCNJ11,KCNK2,KCNK3,KCNMA1,KCNQ2,KCNQ3,KIF2A,KIF5A,KIF5C,L1CAM,LAMA2,MAPT,MDM4,MEF2C,SESN3,ADAM22,MTR,MYH3,MYO5A,NDP,NFE2L2,NPY,HCN1,OCRL,OPHN1,PAH,TREM2,PAK3,PAX6,PC,PCMT1,PDYN,ABCB1,SERPINI1,PIK3CD,FTO,PSAT1,PMS2,POLG,PPM1B,PTPA,RELN,CNNM2,PTCH1,PEX2,PEX5,QDPR,RET,PRRT2,LGI2,RPE65,STX1B,SCN2A,SCN2B,SCN3A,SCN7A,SCN8A,FOXRED1,SGK1,ARX,NTNG1,SLC1A2,SLC1A3,SLC4A3,PEX26,SLC6A1,SLC6A8,SLC6A9,CCDC88A,SLC12A2,NAPB,SLC20A2,SMARCA4,SMARCE1,MBD5,SNRPN,SOX2,SOX3,SOX10,SOX11,SPTAN1,IQSEC2,SSTR1,SSTR2,MAPK8IP3,STX1A,STXBP1,MLC1,ABCC8,ARHGEF9,VPS13A,PLCB1,SYN1,SYN2,CAMSAP2,CNTN2,TCF4,SATB2,SZT2,NSD1,CRB1,AP4E1,TK2,TLR4,KAT6B,RBFOX2,SMUG1,TRH,TRPM2,TSC1,TSC2,TUBB2A,UBE3A,UGT8,VLDLR,BEST1,RBFOX3,NSD2,ELFN1,CELF4,LMAN2L,TUBA1A,SLC17A7,KCNAB1,SLC17A6,EPM2A,GOPC,AAAS,SLC4A10" Disease C0036572 Seizures DisGeNET Curated 1.69E-23 2.09E-19 5.03E-20 5.03E-19 290 982 "ABAT,ACADM,ASIC2,ACHE,ARID1A,ADAR,SLC12A5,ADORA2A,ADRA1B,ADRB2,PCDH19,AGT,CC2D2A,PLA2G6,ALAD,AMPD2,AMPH,AMT,ANK1,APBB1,KCNAB2,DGKD,APP,AQP4,CASK,ASCL1,ASPA,ALDH4A1,ATM,ATP1A2,ATP2A2,ALDH7A1,ADAM23,MPDZ,BCHE,BCS1L,NRP2,SYNJ1,ARHGEF7,SGCE,CA8,CACNA1A,CALB1,CBS,CCK,KRIT1,AP4M1,LGI1,LARGE1,ADGRG1,CHRM1,CHRNA4,CHRNB2,SLIT2,NRXN1,CLU,TPP1,NIPBL,CNR1,RTTN,CPS1,PREPL,CREM,SH2B1,CRMP1,CNTNAP2,RUBCN,HDAC4,DBT,DNAJC6,ZNF804A,MAGI2,SV2A,SRGAP3,ARNT2,DNM1,MED12,SLC12A6,DRD1,GNE,DYRK1A,DNM1L,SEZ6L2,EDN1,EDN3,EEF1A2,EGFR,EGR3,AASS,BSCL2,EML1,EMX2,GPHN,ERCC2,ADGRV1,EYA1,NRN1,FCGR3A,FKTN,FGF13,FGFR1,FGFR3,BAIAP2,FOXG1,AFF2,POMT1,STAMBP,TBR1,AP4B1,GABBR1,GABRA1,GABRA4,GABRA5,GABRB1,GABRG2,GAD1,GAD2,GALC,ATP8A2,CPLX1,GCK,TUBGCP4,TUBA8,GFAP,MMADHC,GK,GLDC,GLI2,GLUL,GNAO1,GNAS,GNG3,PCLO,GRIA1,GRIA2,GRIK1,GRIK2,GRIN1,GRIN2C,GRM2,GRM3,GRM5,GRM7,GRM8,AP4S1,MAN1B1,HMGB1,JAK2,KCNA1,KCNA2,KCNC1,KCND2,KCNH1,KCNH2,KCNJ10,KCNJ11,KCNK2,KCNQ2,KCNQ3,KIF2A,KIF5C,L1CAM,LAMA2,MAPT,MBNL1,MEF2C,SESN3,ADAM22,MT3,MTR,MYH3,MYO5A,NCAM1,NDP,NOS1,NPY,HCN1,OCRL,OPHN1,PAH,TREM2,PAK3,PC,PDYN,ABCB1,SERPINI1,PIK3CD,PSAT1,PMS2,POLG,PPM1B,MAPK3,MAPK10,PRODH,PROX1,RELN,CNNM2,PIGG,PTCH1,PLPPR1,PEX2,PEX5,QDPR,RET,PRRT2,RPE65,STX1B,RYR1,ATXN2,SCN2A,SCN3A,SCN8A,ASIC4,FOXRED1,ARX,NTNG1,SLITRK3,CNKSR2,SLC1A2,SLC1A3,PEX26,SLC6A1,SLC6A8,SLC6A9,SLC8A1,RAB3GAP1,SLC8A3,CCDC88A,SLC12A2,SLC20A2,SMARCA4,SMARCE1,MBD5,SNRPN,MYO16,SOX2,SOX3,SOX10,SOX11,SPTAN1,IQSEC2,LMO3,SRPK2,SST,SSTR2,MAPK8IP3,STXBP1,MLC1,ABCC8,ARHGEF9,VPS13A,SYN1,SYN2,TAC1,CNTN2,TCF4,SATB2,SZT2,SLC19A3,CRB1,AP4E1,TIMP4,TK2,TLR4,TNFRSF1B,KAT6B,CABIN1,TNS1,SEZ6L,SMUG1,TRH,TSC1,TSC2,TUBB2A,UBE3A,UGT8,PDIA2,VLDLR,RBFOX3,NSD2,ELFN1,ANKS1B,SLC30A3,MFF,DNALI1,LMAN2L,TUBA1A,SLC17A7,SNX14,AAAS" Disease C0005586 Bipolar Disorder DisGeNET Curated 2.04E-23 2.52E-19 5.03E-20 5.03E-19 232 730 "SYN3,ASIC2,ADCY2,ADCY8,ADCYAP1R1,BRAP,ADRB2,AGT,SORCS2,PLA2G6,DPP10,ANK3,APP,ARNTL,ARRB2,ASTN1,ATP1A1,ATP1A2,ATP1A3,ATP2A2,BCHE,FGF17,BID,SYNJ1,ARHGEF7,WASF1,CACNA1A,CACNA1B,CACNA1D,CACNB2,CALB1,CAMK2A,HIP1R,CBS,CCK,P2RX6,DCLK1,MAGI1,NDST3,NRXN1,FADS2,CNR1,WHRN,CLOCK,CREM,CRHBP,CRY2,NCOR2,ABCG1,TENM4,SEC24C,FEZ1,ARHGEF10,CSNK1E,NCAN,CNTNAP2,PLCXD3,CTNND2,DGKB,DBN1,ZNF804A,MAGI2,DLG2,DLG3,DLG4,DLX1,GRIN3A,SLC12A6,DPYSL2,DRD1,DRP2,DSCAM,TOM1,EDNRA,RASGRP1,EGFR,EGR3,ELAVL2,EMX2,ERBB4,NRN1,FABP7,ACSL4,PTK2B,RACK1,PPP1R1B,FGFR1,FOXO3,NBEA,PDLIM5,CAMKK2,NRG3,FYN,GABRA1,GABRA3,GABRA4,GABRA5,CHL1,GABRB1,GABRB3,GABRG1,GAD1,GAD2,GAP43,DISC1,CPLX2,CPLX1,TUBA8,GFAP,NTNG2,HPGDS,GNAL,MCHR1,PCLO,GRIA1,GRIA2,GRIA4,GRID1,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2C,NR3C1,GRM3,GRM5,GRM7,PTPN5,HTR2A,HTR5A,IGF1,INPP1,ITGAM,KCNN3,KCNQ2,KCNQ3,MAOB,MAP2,MAPT,DBNL,MTR,MDGA1,NCAM1,NEFM,NFIX,NOS1,NPTX1,NRGN,NTRK2,P2RX7,P2RY1,PAH,PDE4A,PDE4B,PDYN,PFKFB3,ZDHHC8,ABCB1,FTO,POLG,POU3F2,MINDY2,PPP2R2C,PTPA,PPP3CB,PPP3CC,PRKCZ,MAPK3,PRODH,RELN,PSD,BDNF-AS,RASGRF1,RFX4,RGS4,PRIMA1,PBRM1,RORB,S100B,SCN8A,PPP1R9A,NTNG1,FNDC3A,NLGN1,SLC1A2,SLC1A3,SLC1A6,SNAP25,MBD5,DOK5,SP4,NPAS3,LMO3,SST,MAPK8IP3,NEK4,MLC1,PLCB1,SYN2,SYP,ASTN2,TAC1,TACR1,TCF4,CUX2,TCF7L2,RPGRIP1L,SYNE1,DOCK9,SIRT1,ZNF34,TLL2,TLR4,NR2E1,CSMD1,TNR,SEZ6L,NPL,TRPC3,TRPM2,UBC,VGF,VIPR2,ETNPPL,LMAN2L,SLC17A7,MPPE1,SLC17A6,RTN4,ST8SIA2" Disease C0004352 Autistic Disorder DisGeNET Curated 5.24E-22 6.46E-18 1.08E-18 1.08E-17 208 644 "ABAT,DGCR6,ASIC2,CSMD3,ADORA2A,PTCHD1,ADRB2,NLGN4X,PCDH19,AGT,PCDH10,ANK3,CNTNAP1,APBA2,KCNAB2,APC,APP,AQP4,CASK,ATP2B2,DOCK11,MPDZ,NRP2,CACNA1G,NIPA1,CACNA1A,CACNA1D,CACNB2,CBS,CD38,ARHGEF2,CDH8,CDH10,DLGAP2,CHRNA4,CHRNB2,NRXN3,NRXN1,MAGED1,CP,CLOCK,SH2B1,CS,CNTNAP2,CTNND2,DOCK4,ARHGAP32,KATNAL2,RIMS3,ZNF804A,FAM107B,DLG3,DLG4,DLX1,RAB39B,DMD,MED12,SHANK1,SLC12A6,DPYSL2,DRD1,DRP2,DSCAM,DYRK1A,SEZ6L2,ELN,EN2,VPS13B,EPS8,WAC,ACSL4,FOXG1,AFF2,NBEA,TBR1,GABBR1,GABRA1,GABRA2,GABRA3,GABRA4,GABRA5,CHL1,GABRB1,GABRB3,GABRG1,GAD1,GAD2,ZMYND11,DISC1,GATM,GHR,NTNG2,HPGDS,GLUL,GPR37,PCLO,RAPGEF4,GRIA1,GRIA2,GRIK2,GRIK4,GRM5,GRM8,IL1RAPL1,HTR2A,HTR5A,IGF1,PLD5,INPP1,ITGAV,SLC35G1,KCND2,KCNMA1,GPR155,MAOB,MAP2,MARK1,MBD1,MBP,MEF2C,SCAMP5,MTR,NCAM1,NDUFA5,NF1,NOS1,NPTX2,NRCAM,NTRK2,OGG1,OPHN1,OXTR,PAH,CNTN3,PAX6,PCDH9,PDE4A,PDE4B,PDE4D,NLGN3,PIK3CD,JAKMIP1,PLP1,MAGEL2,POLG,PRKCB,MAPK3,MAPK8,HYDIN,PRODH,RELN,PSD,FAM120C,PTPRZ1,RAB3A,SH3TC2,RASGRF1,TMLHE,ROBO1,ROBO2,CLIP1,SCN2A,SCN3A,SCN7A,SCN8A,NLGN4Y,ARX,NTNG1,NLGN1,SLC1A2,SLC1A3,SLC6A8,SHANK2,RIMS1,SNAP25,MBD5,SNRPN,SST,STX1A,STXBP1,SYN1,SYN2,ASTN2,ROBO3,TCF4,NSD1,RNF216P1,TF,SPX,TNFRSF1B,TSC1,TSC2,HEPACAM,CADM1,UBE2H,UBE3A,VLDLR,CLIP2,XPO1,CADM2,LRP8,CSDE1,STMN4,WNK3,JMJD1C,FXR1,NETO1,ST8SIA2" Disease C0233514 Abnormal behavior DisGeNET Curated 1.62E-17 2.00E-13 2.86E-14 2.86E-13 129 365 "BRAP,ADRB2,SEMA6A,ANK3,APP,ARRB2,ATM,ALDH7A1,ARHGEF7,SGCE,CALB1,HAP1,CCK,DCLK1,MAGI1,CHRM4,CHRNA4,DLGAP3,NRXN1,QKI,SULT4A1,NIPBL,CNR1,CLOCK,FEZ1,CTNND2,CX3CR1,NOS1AP,HDAC9,HDAC4,DBI,DCTN1,ZNF804A,PLPPR4,DLG3,DLG4,DMD,MED12,DPYSL2,ATN1,DYRK1A,TMTC1,EGR3,OLIG2,ERBB4,TUBB4A,BAIAP2,STAG2,MEGF10,GABRA1,GABRA2,GABRA3,GABRG2,GAD2,DISC1,MMADHC,GJB1,GPM6A,GRIA1,GRIK2,GRIN1,NR3C1,GRM2,GRM3,GRM5,LINGO1,HTR2A,HTR5A,SLC6A17,L1CAM,STMN1,MAOB,MAP6,MAPT,MARK1,MBNL1,NCAM1,NOS1,NRCAM,NTRK2,OXTR,PAH,TREM2,PDE4B,PDYN,GPR85,NLGN3,MAGEL2,POLG,PPP2R2B,RELN,PSD,PSMD13,PEX2,PEX5,SLC6A15,LRRK2,S100B,LRFN5,SCN2A,SCN8A,PEX26,SHANK2,SMARCA4,SNAP25,SOX5,SP4,GLT8D1,NPAS3,LMO3,POGZ,STX1A,STXBP1,VPS13A,SYN1,SYT4,TAC1,CAMTA1,NSD1,NR2E1,CSMD1,SMUG1,TSC1,TSC2,VGF,ZIC1,ZIC2,CELF4,ST8SIA2" Disease C0025362 Mental Retardation DisGeNET Curated 1.08E-16 1.34E-12 1.67E-13 1.67E-12 247 885 "DGCR6,ARID1A,NLGN4X,PCDH19,NR0B1,CC2D2A,PLA2G6,AMH,AMT,CDC42BPA,ANK1,ANK3,KCNAB2,APC,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,CDK5R1,SYNJ1,WASF1,CA4,CA8,RUNX1T1,CBS,AIFM1,CD38,CDC42,LARGE1,ADGRG1,CLCN4,NRXN1,ABCG2,NIPBL,ARHGEF6,CPS1,SH2B1,RGS6,CNTNAP2,CTNND2,RIMS2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBN1,DBT,DNAJC6,ZEB2,ZBTB24,SACS,SRGAP3,DLG3,DLX1,RAB39B,DMD,DNM1,MED12,TRAPPC9,SLC12A6,DPP6,DSCAM,RCAN1,DYRK1A,USH1C,WDPCP,EEF1A2,AASS,BSCL2,ELN,EMX2,VPS13B,ERCC2,APC2,EYA1,ACSL4,FKTN,FGF13,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,TBR1,GABRA1,CHL1,GABRB3,GAD1,ZMYND11,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,GK,RNPS1,GLDC,GNAS,GPD2,GRIK2,GRIK4,GRIN1,GRM1,GRM7,IL1RAPL1,HBA1,HNRNPK,AGFG1,ATCAY,IDH3B,IGF1,TMEM240,IL12A,ZNF385B,ITGA7,KCNJ10,KCNJ11,KCNQ2,L1CAM,LAMA2,LAMP2,LIG4,MAOB,MAPT,MEIS2,MTR,MYCN,MYO5A,MYO7A,NEXMIF,MYT1,NF1,NFIX,NRCAM,OCRL,OMG,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,NLGN3,PLP1,MAGEL2,NXPH1,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,PEX5,QDPR,RBBP8,RET,PRRT2,RGR,RLBP1,SETD5,ROM1,RPE65,LGR4,SALL1,SCN2A,SCN3A,SCN8A,FOXRED1,ARX,NTNG1,CNKSR2,SLC6A8,RAB3GAP1,SHANK2,SMARCA4,CDK5RAP2,SMARCE1,SNAP25,SNRPN,MYT1L,SOX3,SOX5,SOX10,SOX11,ZNF423,ARHGAP26,IQSEC2,NPAS3,POGZ,KANK1,STXBP1,ABCC8,ARHGEF9,SYP,SYT1,DDHD2,TAL1,TCF4,DMXL2,SATB2,RPGRIP1L,WASHC4,NSD1,DICER1,CRB1,THRA,KAT6B,RBFOX2,TRH,TRPS1,TSC1,TSC2,TUB,HEPACAM,CADM1,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,ZBTB16,FTSJ1,TUBA1A,NELFE,KAT6A,NUP214,NLRP3,AAAS,FXR1,SLC4A10,GAN" Disease C0011570 Mental Depression DisGeNET Curated 9.66E-14 1.19E-09 1.32E-10 1.32E-09 164 554 "CSMD2,NDRG2,ADCY5,ADCY8,ADCYAP1R1,ADRB2,KIDINS220,AGT,PLA2G6,SRPX,ALK,ANK1,APP,AQP4,ARNTL,ARRB1,ARRB2,ATM,ATP1A3,ATP2A2,ALDH7A1,FGF17,DST,SGCE,WASF1,CALM1,CAMK2A,CBS,KRIT1,RGN,LGI1,CHRNA4,CHRNB2,NRXN1,CLU,CNR1,MAGED1,COX4I1,CLOCK,CRHBP,CRY2,ARHGEF10,CX3CR1,NOS1AP,HDAC9,HDAC4,DGKB,SIRPA,DLG4,MED12,DPYSL2,DRD1,ATN1,ABCC9,EDN1,EGFR,EGR3,EPHB1,EYA1,FABP7,ACSL4,PPP1R1B,FGF13,FGFR1,FOLH1,GABRA3,CHL1,GABRB3,GAD1,GAP43,DISC1,CPLX2,CPLX1,GFAP,C1QL1,PPARGC1A,GLUL,GPM6A,MCHR1,GPR26,PCLO,RAPGEF4,GRIA1,GRID1,GRIK3,ADAMTS13,GRIN1,NR3C1,GRM1,GRM3,GRM5,GRM7,CIT,HP,HSP90AA1,HTR2A,IGF1,IL6R,SLC35G1,KCNK2,KIT,STMN1,MAOB,STK32C,MT3,MTR,NCAM1,NEFM,NELL1,SLCO1C1,NOS1,NPY,HCN1,NTRK2,NTRK3,OGG1,OXTR,P2RX7,PDE4A,PDE4B,PDE4D,PDE1B,PDYN,PENK,PFKFB3,ABCB1,FTO,NXPH1,PPP3CC,PRKCB,MAPK3,MAPK8,RELN,BDNF-AS,SLC6A15,S100B,NLGN4Y,SLC1A2,SLC6A1,SIRT2,SLC12A2,ATF7IP,SNAP25,SNCA,SOX2,LMO3,SSPO,SYN1,SYP,TAC1,TACR1,TAL1,WWC1,SYNE1,CRTC1,DICER1,TGFBR3,TLR4,TNFRSF1B,TRH,VGF,VIPR2,VLDLR,SLC4A10" Disease C0338656 Impaired cognition DisGeNET Curated 3.86E-13 4.75E-09 4.75E-10 4.75E-09 178 625 "SERPINA3,ACHE,ADD3,PCDH19,PLA2G6,AMPH,BIN1,ANK3,APBB2,APOC1,APP,AQP4,KIF1A,BCHE,SYNJ1,NIPA1,CACNA1A,CAMK2A,CAPN3,RUNX1T1,CBR1,CBS,AIFM1,DCLK1,LARGE1,CDR1,NOG,CRLF1,CHN1,CHRNA4,ARHGAP22,CLU,FBXO7,SULT4A1,CNR1,COL4A5,CLOCK,CRMP1,CSF1R,CNTNAP2,CTNND2,CX3CR1,CYBB,HDAC9,DBN1,MAGI2,RAB39B,DMD,DRD1,DYRK1A,DNM1L,EEF1A2,AASS,ENO2,ERCC2,RTN3,NRN1,FKTN,FGF14,FGFR3,BAIAP2,PRKAG2,FOXG1,SEC23B,POMT1,CELF1,NRG3,OGA,FYN,CHL1,GAD1,GAD2,DISC1,CPLX2,CYP46A1,GFAP,GJB1,GLUL,GNAS,GRIA2,ADAMTS13,NR3C1,GRM2,GRM3,GRM5,IL1RAPL1,WIF1,HRH3,HP,AGFG1,HTR5A,IGF1,IGFBP1,IL6R,TMEM240,ITGA7,KCNQ2,LAMA2,LAMP2,MAP2,MAPT,MEF2C,MTR,MX1,NF1,NFIA,NFE2L2,NFIX,NOS1,NOVA2,SETD4,OCRL,OPHN1,OXTR,TREM2,PAK3,PDE4A,PDE4D,ABCB1,PIK3CD,FTO,PMP22,POLG,MAPK8,PRODH,RELN,VPS13C,APTX,PEX2,PEX5,RBBP8,SLC6A15,LRRK2,S100B,ATXN1,SCN2A,SCN8A,COPZ1,SLC1A2,SLC1A3,PEX26,SLC6A8,SLC6A9,SHANK2,SLC20A2,SNAP25,SNCA,NMNAT2,SPP1,SPART,SRPK2,CLSTN2,SST,ABCC8,SYP,ASTN2,CNTN2,WWC1,TCF4,SATB2,CRTC1,ATP13A2,SIRT1,TLR4,NR2E1,SMUG1,NEIL2,TSC1,VLDLR,VSNL1,RBFOX3,CLIP2,XRCC4,FTSJ1,EPM2A,GJC2,NLRP3,AP3B2" Disease C1510586 Autism Spectrum Disorders DisGeNET Curated 2.14E-12 2.64E-08 2.40E-09 2.40E-08 133 436 "DGCR6,ADORA2A,PTCHD1,NLGN4X,PCDH19,AMT,DPP10,ANK3,APBA2,APC,CASK,ATP2B2,MPDZ,CACNA1G,CACNA1A,CACNA1D,CACNB2,CARS,CD38,CDH2,CDH8,TAOK2,NRXN3,NRXN1,NRXN2,SH2B1,CNTNAP2,CTNND2,ARHGAP24,ZNF804A,KIAA0319,ARNT2,DLG4,DLX1,RAB39B,DNM1,SHANK1,DPP6,DRD1,DYRK1A,SEZ6L2,KMT5B,EN2,VPS13B,GPHN,ERBB4,FABP7,BAIAP2,FOXG1,AFF2,NBEA,TBR1,GABRB3,GABRG1,GAD1,SRRM4,GFAP,KIRREL3,GPR37,GRIK4,NR3C1,GRM5,GRM7,GRM8,IL1RAPL1,HTR2A,ICA1,LRRTM3,KCNJ10,L1CAM,LIG4,GPR155,MAOB,MARK1,MEF2C,MOG,NEXMIF,NOS1,ZNF713,OXTR,PAH,PAX6,PCDH9,NLGN3,PIK3CD,JAKMIP1,MAGEL2,NXPH1,POU3F2,LRRN3,CEP41,PRKCB,MAPK10,RELN,PSD,BDNF-AS,FEZF2,PRRT2,TMLHE,ROM1,SCN2A,ARX,NLGN1,SLC6A8,SHANK2,TET1,SNAP25,MBD5,MYO16,SOX5,ZNF423,POGZ,PLCB1,SYN1,SYN2,ASTN2,TBL1X,TCF4,SATB2,SYNE1,HEY1,SEZ6L,TRIO,TSC1,TSC2,CADM1,UBE3A,XPO1,PCDH15,JMJD1C,CBLN2,ST8SIA2,GAN" Disease C1269683 Major Depressive Disorder DisGeNET Curated 7.85E-12 9.68E-08 8.07E-09 8.07E-08 147 505 "ACHE,ADAR,ADCY5,ADCYAP1R1,ANK3,APAF1,APP,ARRB1,ALDH7A1,PROM1,BMP7,DST,CALB2,KALRN,CAMK2A,KYAT1,CHRNA4,FADS2,QKI,CNR1,ABI3BP,CLOCK,CREM,CRHBP,SEC24C,NCAN,CNTNAP2,CTNND2,NRSN1,EARS2,ZNF804A,NTM,DLG2,DLG3,DLG4,OLIG1,MED12,DRD1,EDN1,EDNRA,EGFR,EPHB1,TLR7,PPP1R1B,FGF13,FGFR1,PDLIM5,GABBR1,GABRA3,GAD1,GAD2,GALC,DISC1,WASF3,GFAP,C1QL1,GLUL,GPM6A,PCLO,TPPP,GRIA1,GRIA2,GRIA4,GRIK4,NR3C1,GRM2,GRM3,GRM5,GRM7,GRM8,CIT,PSIP1,HLF,ELOVL5,HP,HSPA1L,HSP90AA1,HTR2A,KCNK2,STMN1,LSAMP,MAG,MAOB,MAP2,MDM4,MOG,MDGA1,NEXMIF,NCAM1,NELL1,NOS1,NPY,NRGN,NTRK2,NTRK3,OXTR,P2RX7,PDE4A,PDE4B,PDYN,PFKFB3,ABCB1,FTO,PLP1,PRKCB,MAPK3,RELN,PSMD13,BDNF-AS,PTX3,SLC6A15,RGS4,PRIMA1,S100B,LRFN5,SGK1,SLC1A2,SLC1A3,SLC1A6,FAM214B,ATF7IP,SNAP25,MYT1L,GLT8D1,NPAS3,LHPP,SST,PLCB1,TAC1,TAL1,CRTC1,SIRT1,ZNF34,CBX5,TNFRSF1B,METTL3,SMUG1,TRH,AMACR,VGF,VIPR2,VLDLR,RBFOX3,ZBTB16,LRP8,SLC17A7,SLC17A6" Disease C0011581 Depressive disorder DisGeNET Curated 8.96E-12 1.11E-07 8.09E-09 8.08E-08 189 697 "CSMD2,NDRG2,ADCY5,ADCY8,ADCYAP1R1,ADRB2,KIDINS220,AGT,PLA2G6,SRPX,ALK,ANK1,APP,AQP4,ARNTL,ARRB1,ARRB2,ATM,ATP1A3,ATP2A2,ALDH7A1,BCS1L,FGF17,DST,SGCE,WASF1,CALM1,CAMK2A,CBS,KRIT1,RGN,LGI1,CHRNA4,CHRNB2,NRXN1,CLU,CNR1,MAGED1,COX4I1,CP,CLOCK,CRHBP,CRY2,SNCAIP,CSF1R,ARHGEF10,CX3CR1,NOS1AP,HDAC9,MATR3,DGKB,SIRPA,DCTN1,DLG4,MED12,DPYSL2,DRD1,ATN1,ABCC9,EDN1,OPTN,EGFR,EGR3,ELN,EPHB1,ERBB4,EYA1,FABP7,ACSL4,PPP1R1B,FGF13,FGFR1,FOLH1,GABRA3,CHL1,GABRB3,GAD1,GAP43,DISC1,CPLX2,CPLX1,GFAP,C1QL1,PPARGC1A,GLUL,GNAS,GPM6A,MCHR1,GPR26,PCLO,RAPGEF4,GRIA1,GRID1,GRIK3,ADAMTS13,GRIN1,NR3C1,GRM1,GRM3,GRM5,GRM7,CIT,HP,HSP90AA1,HTR2A,IGF1,IL6R,SLC35G1,KCNK2,KIT,STMN1,MAOB,MAPT,STK32C,MT3,MTR,NCAM1,NEFM,NEFH,NELL1,SLCO1C1,NOS1,NPY,HCN1,NTRK2,NTRK3,OCRL,OGG1,OXTR,P2RX7,PAH,TREM2,PDE4A,PDE4B,PDE4D,PDE1B,PDYN,PENK,ABCB1,FTO,PMS2,POLG,NXPH1,PPP2R2B,PPP3CC,PRKCB,PRKCG,MAPK3,MAPK8,PRPH,RELN,BDNF-AS,SLC6A15,S100B,ATXN2,NLGN4Y,SLC1A2,SLC6A1,SIRT2,SLC12A2,SLC20A2,ATF7IP,SNAP25,SNCA,SOX2,LMO3,SSPO,SYN1,SYP,TAC1,TAC3,TACR1,TAL1,WWC1,SYNE1,CRTC1,DICER1,SIRT1,TGFBR3,TLR4,TNFRSF1B,TRH,AMACR,CADM1,VGF,VIPR2,VLDLR,CLIP2,SLC4A10" Disease C0041696 Unipolar Depression DisGeNET Curated 9.18E-12 1.13E-07 8.09E-09 8.08E-08 127 418 "ADAR,ADCY5,ADCYAP1R1,ANK3,APAF1,APP,ARRB1,PROM1,BMP7,DST,KALRN,CAMK2A,KYAT1,CHRNA4,QKI,CNR1,ABI3BP,CLOCK,CREM,CRHBP,SEC24C,NCAN,CNTNAP2,CTNND2,NRSN1,HDAC9,ZNF804A,NTM,DLG2,DLG3,DLG4,MED12,DRD1,EDN1,EGFR,EPHB1,TLR7,PPP1R1B,FGF13,FGFR1,PDLIM5,GABBR1,GABRA3,GAD1,GAD2,DISC1,WASF3,GFAP,C1QL1,GLUL,GPM6A,PCLO,TPPP,GRIA1,GRIA2,GRIA4,GRIK4,NR3C1,GRM1,GRM5,GRM7,GRM8,CIT,PSIP1,HLF,HP,HSPA1L,HSP90AA1,HTR2A,HTR5A,KCNK2,LSAMP,MAOB,MAP2,MDM4,MDGA1,NEXMIF,NCAM1,NELL1,NOS1,NPY,NRGN,NTRK2,NTRK3,OXTR,P2RX7,PDE4A,PDE4B,PDYN,PFKFB3,ABCB1,FTO,PRKCB,MAPK3,RELN,PTX3,SLC6A15,RGS4,PRIMA1,S100B,LRFN5,SGK1,SLC1A2,SLC1A3,SLC1A6,SNAP25,MYT1L,GLT8D1,NPAS3,LHPP,CLSTN2,SST,PLCB1,TAL1,WWC1,SIRT1,CBX5,TNFRSF1B,METTL3,TRH,AMACR,VGF,VLDLR,RBFOX3,ZBTB16,LRP8,SLC17A6" Disease C0004936 Mental disorders DisGeNET Curated 1.11E-11 1.37E-07 8.62E-09 8.61E-08 104 321 "SLITRK1,ADCYAP1R1,ADRB2,SEMA6A,ANK3,ARRB2,ALDH7A1,ARHGEF7,SGCE,CACNB2,CALB1,CCK,DCLK1,MAGI1,CHRM4,CHRNA4,NRXN1,QKI,SULT4A1,CNR1,CLOCK,CRHBP,FEZ1,CTNND2,NOS1AP,HDAC9,ZNF804A,PLPPR4,DLG4,DMD,MED12,DPYSL2,DYRK1A,TMTC1,EGR3,OLIG2,ERBB4,ACSL4,TUBB4A,BAIAP2,PDLIM5,GABRA3,GAD1,DISC1,GFAP,PCLO,GRIA1,GRIK4,GRIN1,NR3C1,GRM5,HTR2A,HTR5A,ATCAY,STMN1,MAG,MAOB,MARK1,MYT1,NCAM1,NOS1,NPY,NRCAM,NRGN,NTRK2,NUCB2,OXTR,PAH,KCNK10,TREM2,PDE4B,PDYN,GPR85,ABCB1,FTO,MAGEL2,PPP2R2B,RELN,PSD,PSMD13,BDNF-AS,SLC6A15,RGS4,RIT2,LRRK2,S100B,ATXN1,LRFN5,SCN8A,ATF7IP,SNAP25,SP4,GLT8D1,NPAS3,LMO3,SYT4,TACR1,TAL1,ACSL6,NR2E1,CSMD1,VGF,VLDLR,ST8SIA2" Disease C0001973 "Alcoholic Intoxication, Chronic" DisGeNET Curated 1.17E-11 1.44E-07 8.62E-09 8.61E-08 123 402 "ABAT,DSCAML1,ADCY5,BRAP,NLGN4X,AGT,SEMA6A,PCDH10,ALK,CPNE5,ASTN1,MPDZ,DST,ARHGEF7,SGCE,CAMK2A,CARS,CCK,CCKBR,CDH8,CDH10,CDH18,CHM,CHRNA4,NRXN3,CNR1,CLOCK,CRHBP,CNTNAP2,KIAA0040,ST18,CNIH3,DPYSL2,DRD1,ATN1,EDNRB,EGFR,ELAVL2,GPHN,PTK2B,RACK1,TESK2,PPP1R1B,SGIP1,FYN,GABBR1,GABRA1,GABRA2,GABRA5,GABRB1,GABRB3,GABRG1,GABRG2,GAD1,GAD2,GALR1,GAP43,GFAP,PPARGC1A,GLI2,GLUL,LILRA1,GRIK1,GRIK3,GRIN1,GRIN2C,GRM1,GRM2,GRM3,GRM5,GRM7,GRM8,HMGB1,HNMT,HTR2A,KCNK3,KCNN3,MAOB,MARK1,MBP,MOBP,MOG,TAGLN3,NCAM1,NEUROD2,NF1,NOS1,NPY,NRDC,NTRK2,OPRL1,PDE4B,PDYN,PENK,CYTL1,PIK3CD,PIK3R1,FTO,PPARA,NKAIN1,RASGRF2,RFX4,RGS4,SLC1A2,SLC1A3,SLC6A1,PKNOX2,SLC6A9,SNCA,LMO3,NKAIN2,KANK1,ARC,SYN2,TAC1,TACR1,TF,TLR4,HEY2,CDK20,TRH,XRCC4,LRP8" Disease C0525045 Mood Disorders DisGeNET Curated 1.19E-11 1.47E-07 8.62E-09 8.61E-08 102 313 "ABAT,ACHE,NDRG2,ADCY8,SLC12A5,ADORA2A,ADRA1B,ADRB2,ANK3,ARNTL,ARRB2,ATP2A2,DST,ARHGEF7,CACNA1D,P2RX6,CBFA2T2,CDH2,CNR1,CLOCK,CRHBP,CRY2,ABCG1,RGS6,SEC24C,NRSN1,HDAC9,HDAC4,DCTN1,ZNF804A,DLG3,DLG4,DMD,DRD1,EDN1,BSCL2,PPP1R1B,FOXO3,GABRA1,GABRA3,GABRA5,CHL1,GAD1,GAD2,GAP43,DISC1,GFAP,C1QL1,RNPS1,HPGDS,GLI2,GLUL,MCHR1,PCLO,TPPP,GRIA1,GRIK2,NR3C1,GRM2,GRM3,HP,HSP90AA1,HTR2A,HTR5A,MAOB,MAP2,NCAM1,NOS1,NPY,NTRK2,NTRK3,TBC1D25,P2RX7,P2RY1,PAX6,PDYN,PFKFB3,PIK3CD,PIK3R1,FTO,SMOX,MAGEL2,POLG,PRKCZ,RELN,S100B,HES6,SLC1A2,SIRT2,ATF7IP,SST,VPS13A,PLCB1,TAC1,TACR1,CRTC1,SIRT1,ZNF34,VGF,VIPR2,FZD3,ST8SIA2" Disease C0543888 Epileptic encephalopathy DisGeNET Curated 2.78E-11 3.42E-07 1.90E-08 1.90E-07 32 57 "SLC12A5,PCDH19,KCNT1,CASK,CACNA1A,CACNA2D2,NRXN1,DNM1,EEF1A2,CELSR3,GPHN,GABRA1,GABRB3,GNAO1,GRIN1,DOCK7,KCNA2,KCNB1,KCNQ2,HCN1,POLG,MAPK10,SCN2A,SCN8A,ARX,SLC6A1,NAPB,SPTAN1,STXBP1,ARHGEF9,PLCB1,SZT2" Disease C1263846 Attention deficit hyperactivity disorder DisGeNET Curated 3.17E-11 3.90E-07 2.05E-08 2.05E-07 108 343 "SYN3,AS3MT,SLITRK1,ADORA2A,PTCHD1,ADRA1B,APP,ARNTL,BCHE,NRP2,KALRN,KYAT1,DCLK1,CHRNA4,CHRNB2,FADS2,NIPBL,CNR1,CNTFR,CLOCK,SH2B1,SEC24C,NCAN,CNTNAP2,CALY,NRSN1,ZNF804A,SPOCK3,DMD,MED12,SLC12A6,DPP6,DRD1,GNE,EDNRA,RBM12,ELN,EPHB1,ERBB2,CACNG2,PPP1R1B,BAIAP2,NRG3,DISC1,CPLX2,GP1BB,GRM1,GRM5,GRM7,GRM8,HTR2A,IGF1,KCNJ5,LIG4,MAOB,MARK1,GIT1,MYCN,MYT1,NCAM1,NF1,NOS1,NPY,NTRK2,NTRK3,OCRL,OPHN1,OXTR,PAH,PRTG,PDE4D,PIK3CD,FTO,PMS2,MAGEL2,PRKCG,DIRAS2,BDNF-AS,PTPRD,PTPRN2,RAB3A,S100B,ATXN1,SCN8A,SLC1A3,SLC6A8,SNAP25,SNRPN,IQSEC2,LMO3,EPB41L3,STX1A,VPS13A,SYP,ASTN2,TAC1,TACR1,ADGRL3,NSD1,TSC1,TSC2,HIRA,UBE3A,VIPR2,CLIP2,ELFN1,MKRN3,LMAN2L" Disease C0003467 Anxiety DisGeNET Curated 4.99E-11 6.15E-07 3.08E-08 3.08E-07 128 432 "DGCR6,ASIC1,ACHE,NDRG2,ADCY5,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AGT,NR0B1,SRPX,ANK3,APC,APP,ARRB2,ATM,ATP1A3,FGF17,SGCE,BAIAP3,CACNA1A,CCK,CCKBR,CHRNA4,DLGAP3,FBXO7,NIPBL,CNR1,MAGED1,ACBD5,CREM,CRHBP,SLITRK5,CTNND2,MATR3,DBI,DCTN1,ZNF804A,DLG4,DNM2,SHANK1,RCAN1,EDN1,OPTN,TENM1,ELN,GPHN,ERBB4,EYA1,F8,FABP7,FGFR1,FOLH1,CAMKK2,NRG3,FYN,GABRA2,GABRB3,GABRG2,GAD1,GAD2,C1QL1,PPARGC1A,GLI2,GNAS,MCHR1,GPR26,GRIA1,GRIA2,NR3C1,GRM8,HTR2A,IGF1,STMN1,FGFBP3,MAPT,MT3,NDP,NEFH,NFIX,NPY,NTRK2,NTRK3,NUCB2,OCRL,OXTR,PAH,TREM2,PAK3,PDE4B,PENK,ABCB1,NLGN3,FTO,PMP22,PMS2,PPP2R2B,PRODH,PRPH,BDNF-AS,LRRK2,S100B,ATXN2,ASIC4,NLGN4Y,SLC1A2,SLC1A3,SLC6A1,TMEM132D,ATF7IP,MBD5,SOX5,SSPO,ARHGEF9,VPS13A,SYN1,TAC1,TAC3,TACR1,TAL1,SIRT1,TRPM2,TSC2,RBFOX3,CLIP2,SLC38A1,AAAS" Disease C0700095 Central neuroblastoma DisGeNET BeFree 7.50E-11 9.25E-07 4.40E-08 4.40E-07 375 1631 "KCNH8,ASIC2,ACHE,NBAT1,ARID1A,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,ADRB2,KIDINS220,HACE1,OSBPL1A,NR0B1,PLA2G6,SEMA6A,ALK,BIN1,ANK2,APAF1,APC,APLP1,APP,LGR5,MADD,ARNTL,ARRB2,ARSF,ASCL1,ASPA,ASPH,PTCH2,DYNLL1,ATM,RIPK1,KIF1A,BARD1,BBS2,BCHE,BCL2L2,BCS1L,CFLAR,PROM1,SYNJ1,ARHGEF7,BTRC,CALM1,PTBP2,NGB,CAMK2B,CAMK2G,CAST,CCK,KRIT1,CCNT1,P2RX6,CD86,CD38,CD81,CDK11B,ARHGEF2,CDC42,DCLK1,LGI1,DLGAP1,CRLF1,NUMBL,CHGA,CHGB,CHM,CHN1,CHN2,SLIT2,CLCN4,CLU,ABCG2,CNR1,SLC25A27,COL11A2,TBPL1,CLOCK,CREM,CRMP1,NCOR2,SNCAIP,CSF1,CSF3R,CSNK1E,GALNT9,CHD5,CTH,SLC45A1,RIMS2,CX3CR1,DOCK4,HDAC9,ARHGAP32,ARHGAP24,ACY3,DAPK3,DCC,TIAM2,POM121,SRGAP3,ARNT2,DLG4,DPYSL2,ATN1,RCAN1,DNM1L,EBF1,EDN1,EDNRA,EDNRB,OPTN,EFNB3,APH1A,EBI3,EGFR,EIF4G2,COPS4,ELAVL2,ELAVL4,DCTN4,ENO2,LRRC17,ERBB2,ERBB4,EFS,ETV1,EXTL1,CEND1,FABP7,PTK2B,TUBB3,ZMYND10,FCGR3A,FGF13,FGFR1,FOXM1,FOXO3,FLT1,SMC2,PDLIM5,TRIM16,CAMKK2,B3GAT1,TPPP3,DKK3,MEGF10,CHL1,B4GALNT1,GAP43,DISC1,GART,WASF3,DNER,GFAP,C1QL1,HPGDS,GLI2,RAB40B,GNAS,PRUNE2,ADAP1,MCHR1,STMN2,RAPGEF1,GRIA2,NR3C1,GRM1,GRM2,GRM5,PTPRT,PTPN5,PSIP1,WIF1,BACH2,HMGB1,NEGR1,HPR,HSP90AA1,HTR2A,ICA1,IGF1,GAREM2,HES5,IL6R,INSM1,ITGAM,ITGAV,JAK2,SLC35G1,KCNH2,KCNJ3,KCNJ5,KIT,KLC1,L1CAM,STMN1,LIFR,LMO1,MAOB,MAP2,MAPT,MAT2A,MATK,MDM4,SHC3,MEIS1,MEIS2,KITLG,MSRA,SCG3,MXI1,MYCN,NAP1L1,NBL1,NCAM1,NEFH,NEUROD1,NF1,NFIA,NFE2L2,NFIX,NHLH1,NKX2-2,NME4,NOS1,NPY,NOVA2,NPPA,NPTX2,SLC11A2,NRDC,NRGN,NTRK2,NTRK3,OPRL1,P2RX7,P2RY1,PBX1,PCMT1,PDGFRA,ENPP2,PDYN,PENK,CYTL1,ABCB1,DUSP26,SERPINE2,PIK3CD,PIK3R1,XRN1,FTO,SMOX,MAPKAP1,PPARA,PPP2R2B,LRRN3,PTPA,PPP5C,MAPK3,MAPK7,MAPK8,MAPK9,PROX1,PRPH,RELN,APTX,PTCH1,PTHLH,PTK2,PTN,PTPRD,RASGRF1,RET,PRRT2,RGS4,ROBO2,LRRK2,MEG3,ATAT1,KCNIP3,WLS,ZNF331,S100B,ATXN2,SCN7A,SFPQ,SGK1,ITSN1,SHMT2,URGCP,NBPF1,SLC6A8,SNAP25,SNCB,SNCA,FAIM2,SNRPN,KDM4B,WDTC1,SOX2,KDM3A,SPP1,ZNF423,KIF1B,MCF2L2,LMO3,MIR100HG,SMOC1,SST,SSTR2,NKAIN2,SULF2,AJAP1,SYN1,SYP,SYT1,TAC1,CAMTA1,UNC5D,WWC1,AGTPBP1,TBCEL,FBXW11,TCF4,NEU4,TCF7,RALYL,NSD1,FRYL,TEK,DICER1,SIRT1,ZFPM2,ZMAT3,TGFBR3,HHIP,SLC44A1,TIAM1,ASXL3,NR2E1,TNFRSF1B,TPM3,TRH,AMACR,TRPC1,TRPM2,TSC1,CADM1,UCHL1,GORASP1,PDIA2,MGAT5B,VAV1,WNT7A,WNK1,MAP3K12,PRDM2,LRP8,EVI5,GDPD5,STMN4,SCG2,NAV2,NELFE,UBE3B,PAK5,CASC15,NUP214,VANGL2,AAAS,ST8SIA2" Disease C0027819 Neuroblastoma DisGeNET Curated 8.62E-11 1.06E-06 4.83E-08 4.83E-07 386 1689 "KCNH8,ASIC2,ACHE,NBAT1,ARID1A,NDRG2,PLEKHG5,ADCY2,ADCYAP1R1,ADRB2,KIDINS220,HACE1,OSBPL1A,NR0B1,PLA2G6,SEMA6A,ALK,BIN1,ANK2,APAF1,APC,APLP1,APP,LGR5,MADD,ARNTL,ARRB2,ARSF,ASCL1,ASPA,ASPH,PTCH2,DYNLL1,ATM,RIPK1,KIF1A,BARD1,BBS2,BCHE,BCL2L2,BCS1L,CFLAR,PROM1,SYNJ1,ARHGEF7,BTRC,CALM1,PTBP2,NGB,CAMK2B,CAMK2G,CAST,CCK,KRIT1,CCNT1,P2RX6,CD86,CD38,CD81,CDK11B,ARHGEF2,CDC42,DCLK1,LGI1,DLGAP1,CRLF1,NUMBL,CHGA,CHGB,CHM,CHN1,CHN2,SLIT2,PPT2,CLCN4,CLU,ABCG2,CNR1,SLC25A27,COL11A2,TBPL1,CLOCK,CREM,CRMP1,NCOR2,CS,SNCAIP,CSF1,CSF3R,CSNK1E,GALNT9,CHD5,CTH,SLC45A1,RIMS2,CX3CR1,DOCK4,HDAC9,ARHGAP32,ARHGAP24,ACY3,DAPK3,DCC,TIAM2,POM121,SRGAP3,ARNT2,DLG4,DPYSL2,ATN1,RCAN1,DNM1L,EBF1,EDN1,EDNRA,EDNRB,OPTN,EFNB3,APH1A,EBI3,EGFR,EIF4G2,COPS4,ELAVL2,ELAVL4,DCTN4,ENO2,LRRC17,ERBB2,ERBB4,EFS,ETV1,EXTL1,CEND1,FABP7,PTK2B,TUBB3,ZMYND10,FCGR3A,FGF13,FGFR1,FOXM1,FOXO3,FLT1,SMC2,PDLIM5,TRIM16,CAMKK2,B3GAT1,TPPP3,DKK3,MEGF10,CHL1,B4GALNT1,GAP43,DISC1,GART,WASF3,DNER,GFAP,C1QL1,HPGDS,GLI2,RAB40B,GNAS,PRUNE2,ADAP1,MCHR1,STMN2,RAPGEF1,GRIA2,NR3C1,GRM1,GRM2,GRM5,PTPRT,PTPN5,PSIP1,WIF1,BACH2,HMGB1,NEGR1,HPR,HSP90AA1,HTR2A,ICA1,IGF1,GAREM2,RBPJ,HES5,IL6R,INSM1,ITGAM,ITGAV,JAK2,SLC35G1,KCNH2,KCNJ3,KCNJ5,KIT,KLC1,L1CAM,STMN1,LIFR,LMO1,MAOB,MAP2,MAPT,MAT2A,MATK,MDM4,SHC3,MEIS1,MEIS2,KITLG,MSRA,SCG3,MXI1,MYCN,NAP1L1,NBL1,NCAM1,NEFH,NEUROD1,NF1,NFIA,NFE2L2,NFIX,NHLH1,NKX2-2,NNAT,NME4,NOS1,NPY,NOVA2,NPPA,NPTX2,SLC11A2,NRDC,NRGN,NTRK2,NTRK3,OPRL1,P2RX7,P2RY1,PBX1,PCMT1,PDGFRA,ENPP2,PDYN,PENK,CYTL1,ABCB1,DUSP26,SERPINE2,PIK3CD,PIK3R1,XRN1,FTO,SMOX,MAPKAP1,PMS2,PPARA,PPP2R2B,LRRN3,PTPA,PPP5C,PRKCZ,MAPK3,MAPK7,MAPK8,MAPK9,PROX1,PRPH,RELN,APTX,PTCH1,PTHLH,PTK2,PTN,PTPRD,RASGRF1,RET,PRRT2,RGS4,ROBO2,LRRK2,MEG3,ATAT1,KCNIP3,WLS,ZNF331,S100B,ATXN2,SCN7A,SFPQ,SGK1,ITSN1,SHMT2,URGCP,SLC2A5,NBPF1,SLC6A8,SNAP25,SNCB,SNCA,FAIM2,SNRPN,KDM4B,WDTC1,SOX2,KDM3A,SPP1,ZNF423,KIF1B,MCF2L2,LMO3,MIR100HG,SMOC1,SST,SSTR2,NKAIN2,SULF2,AJAP1,SYN1,SYP,SYT1,TAC1,CAMTA1,UNC5D,WWC1,AGTPBP1,TBCEL,FBXW11,TCF4,NEU4,TCF7,RALYL,NSD1,FRYL,TEK,DICER1,SIRT1,ZFPM2,ZMAT3,TGFBR3,HHIP,SLC44A1,TIAM1,ASXL3,NR2E1,TNFRSF1B,TPM3,TRH,AMACR,TRPC1,TRPM2,TSC1,CADM1,UCHL1,GORASP1,PDIA2,MGAT5B,VAV1,WNT7A,XRCC4,WNK1,MAP3K12,PRDM2,LRP8,EVI5,GDPD5,STMN4,SCG2,SEMA3B,NAV3,NAV2,NELFE,DOCK8,UBE3B,PAK5,CASC15,NUP214,VANGL2,AAAS,ST8SIA2" Disease C1843367 Poor school performance DisGeNET Curated 3.05E-10 3.76E-06 1.51E-07 1.51E-06 173 649 "DGCR6,ARID1A,PLA2G6,AMT,ANK1,ANK3,KCNAB2,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,CA4,CA8,CBS,AIFM1,LARGE1,ADGRG1,CLCN4,NIPBL,ARHGEF6,CPS1,SH2B1,CNTNAP2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBT,DNAJC6,ZBTB24,SACS,DLG3,DMD,DNM1,MED12,SLC12A6,DPP6,DYRK1A,USH1C,WDPCP,EEF1A2,AASS,BSCL2,ELN,EMX2,ERCC2,APC2,EYA1,ACSL4,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,TBR1,GABRA1,GABRB3,GAD1,ZMYND11,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,GK,GLDC,GNAS,GRIK2,GRIN1,GRM1,IL1RAPL1,HBA1,HNRNPK,IDH3B,IGF1,ITGA7,KCNJ10,KCNJ11,KCNQ2,L1CAM,LAMA2,LIG4,MEIS2,MTR,MYCN,MYO5A,MYO7A,NF1,NFIX,OCRL,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,PLP1,MAGEL2,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,PEX5,QDPR,RBBP8,RET,RGR,RLBP1,SETD5,ROM1,RPE65,SALL1,SCN8A,FOXRED1,NTNG1,CNKSR2,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNRPN,MYT1L,SOX5,SOX10,SOX11,ZNF423,IQSEC2,POGZ,KANK1,ABCC8,SYP,DDHD2,DMXL2,SATB2,RPGRIP1L,WASHC4,CRB1,KAT6B,TRH,TRPS1,TSC1,TSC2,TUB,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,ZBTB16,FTSJ1,KAT6A,AAAS,GAN" Disease C0423903 Low intelligence DisGeNET Curated 3.05E-10 3.76E-06 1.51E-07 1.51E-06 173 649 "DGCR6,ARID1A,PLA2G6,AMT,ANK1,ANK3,KCNAB2,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,CA4,CA8,CBS,AIFM1,LARGE1,ADGRG1,CLCN4,NIPBL,ARHGEF6,CPS1,SH2B1,CNTNAP2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBT,DNAJC6,ZBTB24,SACS,DLG3,DMD,DNM1,MED12,SLC12A6,DPP6,DYRK1A,USH1C,WDPCP,EEF1A2,AASS,BSCL2,ELN,EMX2,ERCC2,APC2,EYA1,ACSL4,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,TBR1,GABRA1,GABRB3,GAD1,ZMYND11,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,GK,GLDC,GNAS,GRIK2,GRIN1,GRM1,IL1RAPL1,HBA1,HNRNPK,IDH3B,IGF1,ITGA7,KCNJ10,KCNJ11,KCNQ2,L1CAM,LAMA2,LIG4,MEIS2,MTR,MYCN,MYO5A,MYO7A,NF1,NFIX,OCRL,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,PLP1,MAGEL2,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,PEX5,QDPR,RBBP8,RET,RGR,RLBP1,SETD5,ROM1,RPE65,SALL1,SCN8A,FOXRED1,NTNG1,CNKSR2,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNRPN,MYT1L,SOX5,SOX10,SOX11,ZNF423,IQSEC2,POGZ,KANK1,ABCC8,SYP,DDHD2,DMXL2,SATB2,RPGRIP1L,WASHC4,CRB1,KAT6B,TRH,TRPS1,TSC1,TSC2,TUB,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,ZBTB16,FTSJ1,KAT6A,AAAS,GAN" Disease C4020876 Dull intelligence DisGeNET Curated 3.05E-10 3.76E-06 1.51E-07 1.51E-06 173 649 "DGCR6,ARID1A,PLA2G6,AMT,ANK1,ANK3,KCNAB2,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,CA4,CA8,CBS,AIFM1,LARGE1,ADGRG1,CLCN4,NIPBL,ARHGEF6,CPS1,SH2B1,CNTNAP2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBT,DNAJC6,ZBTB24,SACS,DLG3,DMD,DNM1,MED12,SLC12A6,DPP6,DYRK1A,USH1C,WDPCP,EEF1A2,AASS,BSCL2,ELN,EMX2,ERCC2,APC2,EYA1,ACSL4,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,TBR1,GABRA1,GABRB3,GAD1,ZMYND11,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,GK,GLDC,GNAS,GRIK2,GRIN1,GRM1,IL1RAPL1,HBA1,HNRNPK,IDH3B,IGF1,ITGA7,KCNJ10,KCNJ11,KCNQ2,L1CAM,LAMA2,LIG4,MEIS2,MTR,MYCN,MYO5A,MYO7A,NF1,NFIX,OCRL,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,PLP1,MAGEL2,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,PEX5,QDPR,RBBP8,RET,RGR,RLBP1,SETD5,ROM1,RPE65,SALL1,SCN8A,FOXRED1,NTNG1,CNKSR2,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNRPN,MYT1L,SOX5,SOX10,SOX11,ZNF423,IQSEC2,POGZ,KANK1,ABCC8,SYP,DDHD2,DMXL2,SATB2,RPGRIP1L,WASHC4,CRB1,KAT6B,TRH,TRPS1,TSC1,TSC2,TUB,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,ZBTB16,FTSJ1,KAT6A,AAAS,GAN" Disease C0003469 Anxiety Disorders DisGeNET Curated 3.58E-10 4.41E-06 1.70E-07 1.70E-06 114 382 "DGCR6,ASIC1,ACHE,NDRG2,ADCYAP1R1,ADORA1,ADORA2A,ADRB2,AGT,NR0B1,ALAD,SRPX,ANK3,APC,APP,ARRB2,ATM,SGCE,BAIAP3,CALM1,CCK,CCKBR,CHRNA4,CHRNB2,DLGAP3,FBXO7,QKI,CNR1,MAGED1,ACBD5,CLOCK,CREM,CRHBP,CRY2,SLITRK5,CTNND2,DBI,ZNF804A,MAGI2,DLG4,DNM2,SHANK1,RCAN1,EDN1,TENM1,GPHN,ERBB4,EYA1,F8,FABP7,FOLH1,CAMKK2,NRG3,FYN,GABRA2,GABRB3,GABRG2,GAD1,GAD2,DISC1,C1QL1,PPARGC1A,GLI2,MCHR1,GPR26,GRIA1,GRIA2,NR3C1,GRM5,GRM8,HTR2A,IGF1,STMN1,FGFBP3,LSAMP,MT3,NCAM1,NPY,NTRK2,NTRK3,NUCB2,TBC1D25,OXTR,P2RX7,PDE4B,PENK,ABCB1,NLGN3,FTO,PMP22,PSAT1,PRODH,BDNF-AS,LRRK2,S100B,ASIC4,NLGN4Y,SLC1A2,SLC1A3,SLC6A1,TMEM132D,ATF7IP,MBD5,SSPO,ARHGEF9,SYN1,TAC1,TACR1,TAL1,SIRT1,TRPM2,TSC2,RBFOX3,SLC38A1" Disease C0917816 Mental deficiency DisGeNET Curated 3.95E-10 4.87E-06 1.80E-07 1.80E-06 173 651 "DGCR6,ARID1A,PLA2G6,AMT,ANK1,ANK3,KCNAB2,APP,CASK,ARHGDIA,ASCL1,ASPA,ALDH4A1,ATP1A2,SLC4A4,ALDH7A1,BBS2,MPDZ,BCS1L,PROM1,SYNJ1,CA4,CA8,CBS,AIFM1,LARGE1,ADGRG1,CLCN4,NIPBL,ARHGEF6,CPS1,SH2B1,CNTNAP2,RUBCN,FRMPD4,HDAC4,KIAA0586,DBT,DNAJC6,ZBTB24,SACS,DLG3,DMD,DNM1,MED12,SLC12A6,DPP6,DYRK1A,USH1C,WDPCP,EEF1A2,AASS,BSCL2,ELN,EMX2,ERCC2,APC2,EYA1,ACSL4,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,AFF2,POMT1,TBR1,GABRA1,GABRB3,GAD1,ZMYND11,ATP8A2,GATM,GCK,TUBGCP4,SRCAP,AHDC1,MMADHC,GK,GLDC,GNAS,GRIK2,GRIN1,GRM1,IL1RAPL1,HBA1,HNRNPK,IDH3B,IGF1,ITGA7,KCNJ10,KCNJ11,KCNQ2,L1CAM,LAMA2,LIG4,MEIS2,MTR,MYCN,MYO5A,MYO7A,NF1,NFIX,OCRL,OPA1,OPHN1,PAH,PAK3,PAX6,PC,PDE4D,PLP1,MAGEL2,MAPK10,PRODH,MASP1,CNNM2,PTCH1,PEX2,PEX5,QDPR,RBBP8,RET,RGR,RLBP1,SETD5,ROM1,RPE65,SALL1,SCN8A,FOXRED1,NTNG1,CNKSR2,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNRPN,MYT1L,SOX5,SOX10,SOX11,ZNF423,IQSEC2,POGZ,KANK1,ABCC8,SYP,DDHD2,DMXL2,SATB2,RPGRIP1L,WASHC4,CRB1,KAT6B,TRH,TRPS1,TSC1,TSC2,TUB,UBE3A,VLDLR,BEST1,CLIP2,XRCC4,ZIC2,ZNF711,ZBTB16,FTSJ1,KAT6A,AAAS,GAN" Disease C0040822 Tremor DisGeNET Curated 6.34E-10 7.82E-06 2.79E-07 2.79E-06 68 192 "ACHE,ADAR,ADORA1,ADORA2A,ADRB2,PLA2G6,ARNTL,ASPA,ATM,CDK5R1,SYNJ1,SGCE,CA8,CACNA1A,CHRM4,FBXO7,CP,SLC35F1,RGS6,DNAJC6,DCTN1,BSCL2,ELN,GABBR1,GABRA1,GABRA3,GABRG2,GAD1,GFAP,GJB1,GNAL,ADAMTS13,GRM1,LINGO1,HNMT,HPCA,HTR2A,SLC6A17,KCNA1,KCNA2,KCNC1,LAMP2,MAPT,NEUROD1,HCN1,PAH,SNX10,PLP1,POLG,PPP2R2B,SKOR1,APTX,PEX2,QDPR,LRRK2,SCN2A,SCN8A,SLC30A10,SLC20A2,SNCA,STXBP1,VPS13A,MCF2L,CNTN2,TNNT1,CABIN1,TRH,CLIP2" Disease C0002395 Alzheimer's Disease DisGeNET Curated 1.59E-09 1.96E-05 6.74E-07 6.74E-06 405 1825 "SERPINA3,ACHE,NDRG2,ADCY2,ADD3,SORCS1,ADORA2A,ADRB2,KIDINS220,HECW2,AGT,NR0B1,SORCS2,PLA2G6,SEMA6A,AMPH,KIF6,BIN1,OGT,ANK1,PKP4,APBA2,APBB1,APBB2,APC,APLP1,ALS2,PHYHD1,APOC1,APOC2,APP,AQP4,MADD,ARNTL,ARRB2,PDE8B,ATM,BACH1,BCHE,BCS1L,BID,BLM,PROM1,CDK5R1,SYNJ1,ARHGEF7,NAE1,C5,WASF1,IL33,DDR1,CALB1,CALB2,CALM1,HAP1,PTBP2,NGB,CAMK2A,CAST,CH25H,BRSK2,SPAG9,RUNX1T1,CBS,CCK,CD86,CBFA2T2,CD38,C1orf52,CDC25B,CDC42,CDR1,NOG,CFL2,SOCS6,CHM,CHRM1,CHRNA4,CHRNB2,JAM2,TAOK2,SLIT2,CLCN3,CLU,TPP1,FBXO7,ABCG2,CNR1,SLC25A27,COL11A2,GAL3ST1,CP,CLOCK,CRMP1,SLC32A1,ABCG1,SNCAIP,CSF1,CSF1R,VCAN,CST3,PLXNA4,APPL1,CTNND2,RIMS2,CX3CR1,ECE2,HDAC9,ARHGAP24,HDAC4,DAPK1,DBN1,DDX46,SNAP91,SV2A,DLG3,DLG4,GRIN3A,DMD,DNM1,MED12,DNM2,SHANK1,DOCK2,DPYSL2,DRD1,ATN1,RCAN1,DYRK1A,DNM1L,ABCC9,FIS1,SEZ6L2,EDN1,EEF1A2,OPTN,APH1A,EGFR,EIF4G2,IRAK4,ELAVL2,ELAVL4,DCTN4,ENO2,EPHB1,KCNMB2,GPHN,ERBB4,APC2,RTN3,ECSIT,NRN1,TUBA1B,PTK2B,FCGR3A,PRMT5,PPP1R1B,FGF1,OLFM1,FGFR3,ATP5PD,FOXM1,FOXO3,FOLH1,SPECC1,CELF1,TPPP3,NRG3,BRSK1,OGA,FYN,SDCBP2,MEGF10,GAA,CHL1,GAD1,GAP43,DISC1,CPLX2,CPLX1,CYP46A1,GFAP,GFER,GFRA1,C1QL1,PPARGC1A,TTBK1,RND1,HPGDS,GLUL,PCDH11X,PCSK1N,FERMT2,ADAP1,STMN2,TPPP,GRIA1,GRIA2,GRIK4,GRIN1,NR3C1,GRM2,GRM5,GSN,PTPN5,PSIP1,ATG4C,HRH3,HMGCR,HPCA,ZDHHC15,HP,HSD17B1,HSP90AA1,HTR2A,ATCAY,IGF1,IGFBP1,IL6R,IL6ST,IL12A,LRRTM3,ITGAM,JAK2,KCNB1,KCNMA1,KLC1,LAMP2,STMN1,LIFR,LIMS1,MAOB,MAP2,MAPT,MARK1,MAT2A,MBP,IL17D,LRP1B,MEF2C,MGAT3,MOG,CD200,MSRA,MT3,SCG3,CTNNA3,MTR,MX1,MYH6,MYO6,FXYD6,NCAM2,NDUFA5,NEFM,NEFH,NFIA,NFE2L2,NFIX,NINJ2,NOS1,NPY,NPPA,SLC11A2,NRDC,NRGN,HCN1,NTRK2,OGDH,OGG1,OLR1,P2RX7,P2RY1,TREM2,PAX6,PC,CDK18,PDE4A,ENPP2,PDYN,PENK,PFKFB3,ABCB1,SERPINE2,PIK3CD,PLCL1,FTO,PLTP,PRRX1,POLG,POU3F4,PPARA,PPP1R1A,PPP2R2B,PTPA,PRKACB,PRKAR1B,PRKCB,MAPK3,MAPK8,MAPK10,DCHS2,MASP1,RELN,KLK6,SAMD9,PSD,PTCH1,RAB3A,ZCWPW1,RBBP6,KHDRBS2,RET,PRRT2,NUDT11,FBXW7,ZC3H14,LRRK2,KCNIP3,RXRA,RYR3,S100B,ATXN1,ATXN2,SCP2,SLC30A10,SFPQ,TRA2B,SH3GL2,BCAN,SYBU,NLGN1,ST8SIA1,SLC1A2,SLC1A3,SLC8A1,SLC8A3,SIRT2,SHANK2,ATF7IP,SORCS3,SNAP25,SNCB,SNCA,WDTC1,SOX2,SP4,NMNAT2,LMO3,SRPK2,SST,SSTR2,LRRC4,VAMP1,SYN1,ARC,SYN2,SYP,SYT1,ASTN2,DNMBP,WWC1,WASHC4,AZIN2,SYNE1,SLC19A3,CRTC1,TF,SIRT1,THBS4,THRA,TIMP4,BHLHB9,TLR4,HEY2,KCTD2,TNFRSF1B,SMUG1,TRPM2,NTSR2,TSC2,TTPA,TMEFF2,UCHL1,GORASP1,VLDLR,BEST1,VSNL1,RBFOX3,ANKS1B,SLC30A3,WNK1,SLC30A4,NAV3,SLC17A7,PCBP4,NELFE,PDSS2,HRASLS,NUP214,NLRP3,AAAS,FRMD6,NETO1,SOCS4" Disease C0027765 nervous system disorder DisGeNET Curated 3.68E-09 4.53E-05 1.51E-06 1.51E-05 120 423 "ACHE,ADRB2,PLA2G6,APP,AQP4,ASCL1,ASPA,ATM,ATP1A2,ATP1A3,PROM1,CACNA1A,CACNA1D,CAST,INA,LGI1,CHRNA4,CLU,CLTC,ABCG2,COL9A1,COL9A2,COL9A3,CP,PNKD,CSF1R,CNTNAP2,CST3,HDAC9,DCTN1,KIAA0319,SACS,SV2A,DLG3,GRIN3A,DNM2,SLC12A6,ATL1,EEF1A2,FABP7,TUBB4A,FOXG1,OGA,CHL1,GAD1,GALC,GAP43,DISC1,SEPT9,CPLX2,GFAP,PPARGC1A,GLUL,GRIA2,GRIK1,GRIN2D,HMGB1,ATCAY,HES5,KCNJ5,KCNQ2,L1CAM,MAOB,MAPT,MEF2C,MOG,MTR,NEFH,NEUROD1,NFE2L2,NOS1,NOVA1,NOVA2,OGDH,OPA1,TREM2,PDYN,PENK,ABCB1,FTO,PLP1,PMP22,POLG,MAPK9,PRODH,RELN,APTX,PTHLH,PTX3,QDPR,RET,PRRT2,ATXN1,ATXN2,SCN8A,ASIC4,ARX,CNKSR2,SLC1A2,SLC4A3,RAB3GAP1,SHANK2,SLC12A2,SLC20A2,ATF7IP,ARFGAP1,SNAP25,SNCA,SOX10,VAMP1,VPS13A,NR2E1,TTPA,UBE3A,UCHL1,ZIC1,ZIC2,CELF4,AAAS,GAN" Disease C0038220 Status Epilepticus DisGeNET Curated 4.24E-09 5.23E-05 1.69E-06 1.69E-05 48 122 "ASIC2,SLC12A5,ADORA2A,ANK3,AQP4,PDXK,ATP1A3,ATP2A2,ALDH7A1,ST3GAL5,CD86,ZBED1,CDH2,CNR1,DMD,EGR3,PTK2B,GABRA1,GABRA4,GAP43,GRIA2,GRM1,GRM5,KCNJ10,KCNK2,KCNMA1,LAMP2,MEF2C,NFE2L2,NOS1,NTRK2,NTRK3,POLG,PRODH,RET,SCN2A,SCN8A,SLC1A2,SLC6A1,SLC8A1,SLC8A3,SST,SSTR1,SSTR2,STXBP1,TLR4,AMACR,TSC2" Disease C0524851 Neurodegenerative Disorders DisGeNET Curated 5.04E-09 6.22E-05 1.94E-06 1.94E-05 181 710 "SERPINA3,KCNH8,ACHE,ADORA2A,ADRB2,KIDINS220,PLA2G6,SEMA6A,AMPD2,OGT,APAF1,APBB1,APLP1,ALS2,APP,PDE8B,ASPA,ATM,KIF1A,CDK5R1,MTMR2,NIPA1,CACNA1A,CALB1,CALM1,NGB,CAST,CBS,INA,CDK11B,CDC27,CDC42,CFL2,PPT2,CLU,TPP1,FBXO7,CNR1,PICK1,TBPL1,CP,SNCAIP,CSF1R,CST3,PLXNA4,RIMS2,CX3CR1,HDAC9,MATR3,DCTN1,SACS,DLG4,RAB39B,DNM2,DOCK2,SLC12A6,DPYSL2,ATN1,DYRK1A,DNM1L,ATL1,OPTN,EGFR,EIF4G2,BSCL2,DCTN4,COQ7,ERBB2,ERBB4,TUBB4A,RACK1,FGF1,FOXO3,NOP56,TPPP3,OGA,FYN,GAA,GAD1,GALC,GFAP,PPARGC1A,PCSK1N,ADAP1,PCLO,TPPP,NR3C1,GSN,GSTM5,LINGO1,PADI2,HSP90AA1,HTR2A,IGF1,RBPJ,IL12A,KCND3,STMN1,MAOB,MAPT,MBP,MOG,CD200,MSRA,NEFH,NFE2L2,NPY,NPPA,OGDH,OGG1,OPA1,P2RX7,TREM2,PAK3,PDE4A,PDE4D,PDYN,ABCB1,PIK3CD,PLP1,FA2H,POLG,PPP2R2B,PTPA,PPP5C,PRKAR1B,PRKCG,MAPK8,MAPK9,MAPK10,PRPH,KLK6,NDUFS7,APTX,PTN,PTPN13,OXR1,RASGRF1,RGS10,LRRK2,S100B,ATXN1,ATXN2,ATXN7,SCN8A,SCP2,SGK1,SYBU,SLC1A2,SIRT2,SLC9A5,SNCB,SNCA,SNRPN,SOX3,SPTAN1,KIF1B,SST,ACSBG1,NECAB1,VPS13A,TAC1,SEMA4A,MGRN1,ATP13A2,SIRT1,SLC44A1,BHLHB9,TNR,TRPM2,TTPA,UBC,UBE3A,UCHL1,REEP1,SNX27,NELFE,EPM2A,AAAS,GAN,JPH3" Disease C0009241 Cognition Disorders DisGeNET Curated 7.13E-09 8.79E-05 2.66E-06 2.66E-05 76 235 "ACHE,AGT,AMPH,ANK3,APP,BCHE,CDK5R1,SYNJ1,RUNX1T1,CBR1,CBS,CDR1,NOG,CHRNA4,CNR1,CX3CR1,HDAC9,DBN1,DMD,TRAPPC9,DRD1,DYRK1A,ENO2,NRN1,FGF14,BAIAP2,NRG3,CHL1,GAD1,DISC1,GFAP,GLUL,NR3C1,GRM5,AGFG1,HTR5A,IGF1,MAPT,NF1,NOS1,NOVA2,SETD4,OXTR,PAK3,MAPK10,RELN,SLC6A15,LRRK2,S100B,SCN8A,SLC1A2,SHANK2,SNAP25,SNCA,NMNAT2,SPP1,SPART,SRPK2,SST,SYP,ASTN2,CNTN2,TCF4,SATB2,TLR4,SMUG1,TSC1,UBE3A,VLDLR,VSNL1,RBFOX3,CLIP2,EPM2A,NLRP3,AP3B2,SLC4A10" Disease C0241210 Speech Delay DisGeNET Curated 8.55E-09 1.05E-04 3.10E-06 3.10E-05 49 128 "PLA2G6,ASPA,ALDH7A1,BTK,AIFM1,NRXN1,TPP1,NIPBL,CP,SH2B1,CNTNAP2,DLG3,AASS,BSCL2,FKTN,FGFR1,AFF2,AP4B1,ZMYND11,GATM,KCNJ10,L1CAM,MEF2C,MEIS2,NF1,OPHN1,PAK3,PDE4D,PIK3R1,PLP1,MAGEL2,KANSL1,PSD,SETD5,SLC6A8,SNRPN,MYT1L,SOX5,IQSEC2,CAMTA1,SATB2,ASXL3,KAT6B,UBE3A,VLDLR,NSD2,XRCC4,MKRN3,FTSJ1" Disease C0557874 Global developmental delay DisGeNET Curated 1.28E-08 1.57E-04 4.49E-06 4.49E-05 189 757 "ABAT,ACADM,RBM10,ARID1A,ADAR,PCDH19,PLA2G6,AMPD2,ANK1,KCNAB2,APC,APP,CASK,ARSE,ASPA,ATP1A3,ALDH7A1,KIF1A,BBS2,BCS1L,ST3GAL5,CACNA1D,AP4M1,ZBED1,LARGE1,ADGRG1,NRXN1,COG1,COL11A2,CPS1,PREPL,SH2B1,SEC24C,HDAC4,KIAA0586,DGKB,ZBTB24,ARNT2,DLG3,DMD,MED12,CDON,SLC12A6,DPH1,GNE,DYRK1A,USH1C,EDNRB,EEF1A2,EMX2,ERBB4,ERCC2,APC2,CEND1,EYA1,F5,TUBB3,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,SEC23B,POMT1,AP4B1,NRG3,GABRA1,GABRG2,GAD1,ZMYND11,CPLX1,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,NFU1,GFER,MMADHC,GK,GLI2,GLRB,GNAO1,GP1BB,PCLO,GRIK2,GRM1,CIT,AP4S1,MAN1B1,HNRNPK,IGF1,KCNB1,KCNH1,KCNJ10,KCNJ11,KCNQ2,KCNQ3,KIF2A,KIF5C,LAMP2,LIG4,MAG,MAOB,MAPT,MBP,MEF2C,MEIS2,MID1,MTR,MYO5A,MYO7A,NF1,NTRK2,DDR2,OCRL,OGDH,OPHN1,PAH,PAX6,PC,PCDH8,PDE4D,FTO,PLP1,PMP22,PSAT1,MAGEL2,POLG,POU3F2,PPM1B,PRODH,CNNM2,PTCH1,PTK2,PEX2,PEX5,QDPR,RET,SETD5,ALG9,SCN2A,SCN8A,FOXRED1,PUF60,PEX26,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNAP25,SNRPN,MYT1L,SOX2,SOX3,SOX10,SOX11,EMC1,ZNF423,SPART,POGZ,NKAIN2,STXBP1,ABCC8,DDHD2,CAMTA1,TCF4,SATB2,RPGRIP1L,WASHC4,SZT2,DICER1,AP4E1,ASXL3,KAT6B,TSC1,TSC2,TUBB2A,HIRA,UBE3A,VLDLR,NSD2,XRCC4,ZIC2,MKRN3,UBE3B,KAT6A,AAAS" Disease C0234146 Absent reflex DisGeNET Curated 1.47E-08 1.82E-04 4.78E-06 4.78E-05 39 93 "ADCY6,BIN1,CNTNAP1,ATP1A3,KIF1A,DST,AIFM1,LARGE1,CFL2,CNTN1,DCAF8,DNM2,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,GJB1,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,PEX5,RYR1,SBF1,ATXN1,SNAP25,SOX10,KIF1B,VPS13A,TRIM2,PIK3R5,PDSS1,TTPA,GAN" Disease C0278124 Absent tendon reflex DisGeNET Curated 1.47E-08 1.82E-04 4.78E-06 4.78E-05 39 93 "ADCY6,BIN1,CNTNAP1,ATP1A3,KIF1A,DST,AIFM1,LARGE1,CFL2,CNTN1,DCAF8,DNM2,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,GJB1,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,PEX5,RYR1,SBF1,ATXN1,SNAP25,SOX10,KIF1B,VPS13A,TRIM2,PIK3R5,PDSS1,TTPA,GAN" Disease C0241772 "Reflex, Deep Tendon, Absent" DisGeNET Curated 1.47E-08 1.82E-04 4.78E-06 4.78E-05 39 93 "ADCY6,BIN1,CNTNAP1,ATP1A3,KIF1A,DST,AIFM1,LARGE1,CFL2,CNTN1,DCAF8,DNM2,SLC12A6,DNM1L,SPEG,FKTN,FHL1,GAA,GJB1,LAMA2,OCRL,RETREG1,PMP22,POLG,APTX,PEX2,PEX5,RYR1,SBF1,ATXN1,SNAP25,SOX10,KIF1B,VPS13A,TRIM2,PIK3R5,PDSS1,TTPA,GAN" Disease C0013384 Dyskinetic syndrome DisGeNET Curated 2.04E-08 2.51E-04 6.43E-06 6.43E-05 30 63 "ADCY5,ADORA2A,RGS9,CA8,CNR1,CP,PNKD,DLG4,DPP6,DRD1,EEF1A2,PPP1R1B,FOXG1,HTR2A,KCNMA1,KCNQ2,KCNQ3,MAOB,MEF2C,PDYN,PENK,BDNF-AS,PRRT2,LRRK2,ATXN2,SCN2A,SCN8A,SNCA,MCF2L,RASD2" Disease C0004134 Ataxia DisGeNET Curated 3.55E-08 4.37E-04 1.09E-05 1.09E-04 66 201 "AK2,PLA2G6,SEMA6A,ALK,ANK1,ATM,ATP1A3,ATP2B3,CA8,CACNA1A,CACNB4,CALM1,KRIT1,AIFM1,CACNA2D2,PPT2,TPP1,TBPL1,CP,RGS6,SACS,ATN1,EGR3,ENO2,FGF14,NOP56,GAA,GABRA1,GABRA4,GJB1,GRM1,ATCAY,KCNA1,KCNA2,KCNC2,KCND3,KCNJ10,KCNN3,NPY,HCN1,OGG1,OPHN1,PDYN,POLG,PPP2R2B,PRKCG,APTX,RAD17,UEVLD,ATXN1,ATXN2,ATXN7,SCN8A,SNAP25,TTBK2,VAMP1,CAMTA1,SYNE1,PIK3R5,TRIO,TTPA,UBE3A,UCHL1,ZIC1,ZIC2,SNX14" Disease C0033975 Psychotic Disorders DisGeNET Curated 5.94E-08 7.33E-04 1.79E-05 1.79E-04 91 311 "SERPINA3,KIDINS220,PLA2G6,ALAD,SEMA6A,ANK3,ARNTL,RGS9,ARHGEF7,CACNA1A,CNR1,PICK1,TENM4,FEZ1,CSNK1E,NRSN1,DBI,ZNF804A,DLX1,MED12,SHANK1,SLC12A6,DPYSL2,DRD1,DRP2,OLIG2,ERBB4,RTN3,PPP1R1B,FGFR3,SMC2,B3GAT1,GABRA1,GABRG2,GAD1,DISC1,CPLX2,CPLX1,GHR,HPGDS,GLUL,PCDH11X,GNAS,TPPP,GRIK3,GRIK4,GRIN1,NR3C1,GRM2,GRM3,GRM5,HTR2A,HTR5A,KCNH2,MAOB,MAPT,NDP,NPY,NRGN,PAH,PAK3,ABCB1,FTO,PPP3CC,RELN,RGS4,PBRM1,ALG9,S100B,SAFB,SLC1A2,SLC6A9,SEPHS1,SLC12A2,SLC20A2,TET1,SNAP25,SNCA,SP4,ARHGAP26,NPAS3,VPS13A,WWC1,ACSL6,TCF4,NPL,PDSS1,TRPM2,EPM2A,FZD3,PAK5" Disease C0036857 Severe mental retardation (I.Q. 20-34) DisGeNET Curated 6.75E-08 8.32E-04 1.98E-05 1.98E-04 55 159 "CASK,KIF1A,CACNA1D,CD38,AP4M1,LARGE1,ADGRG1,NRXN1,NIPBL,CNTNAP2,CTNND2,DBT,ZEB2,SRGAP3,DMD,DMPK,EEF1A2,ACSL4,FKTN,FGFR3,FOXG1,POMT1,AP4B1,CPLX1,KIRREL3,CIT,AP4S1,ZDHHC15,KCNH1,L1CAM,LAMA2,MEF2C,NEXMIF,PAH,NALCN,CNNM2,SCN2A,ITSN1,ARX,RAB3GAP1,SHANK2,SPTAN1,IQSEC2,STXBP1,ARHGEF9,TCF4,SATB2,AP4E1,KCNE5,UBE3A,NSD2,ZIC1,TUBA1A,UBE3B,SNX14" Disease C0013362 Dysarthria DisGeNET Curated 7.19E-08 8.87E-04 2.06E-05 2.06E-04 64 196 "ADCY5,PLA2G6,BIN1,PDE8B,ATM,ATP1A2,ATP1A3,BCS1L,SYNJ1,CA8,CACNA1A,CACNB4,FBXO7,RTTN,CP,PNKD,SNCAIP,PNPLA8,RUBCN,MATR3,DNAJC6,DCTN1,SACS,OPTN,NOP56,AP4B1,ATP8A2,GJB1,GRM1,HPCA,KCNA1,KCND3,MAPT,PDYN,SERPINI1,PLP1,POLG,PPP2R2B,PRKCG,APTX,PEX2,ATXN1,ATXN2,SLC30A10,FOXRED1,SLC6A1,SLC20A2,SNAP25,SNCA,SPART,ELOVL4,VAMP1,VPS13A,DDHD2,CAMTA1,DMXL2,SYNE1,KAT6B,PIK3R5,TTPA,VLDLR,XRCC4,AAAS,GAN" Disease C4020875 Mental and motor retardation DisGeNET Curated 7.53E-08 9.28E-04 2.06E-05 2.06E-04 156 614 "ABAT,ACADM,RBM10,ARID1A,ADAR,PLA2G6,AMPD2,ANK1,KCNAB2,APP,CASK,ARSE,ASPA,ATP1A3,ALDH7A1,KIF1A,BBS2,BCS1L,ST3GAL5,CACNA1D,AP4M1,LARGE1,ADGRG1,COG1,COL11A2,CPS1,PREPL,SH2B1,SEC24C,HDAC4,KIAA0586,ZBTB24,ARNT2,DLG3,MED12,CDON,SLC12A6,GNE,USH1C,EDNRB,EEF1A2,EMX2,ERCC2,APC2,EYA1,TUBB3,FKTN,FGFR1,FGFR3,MAD2L2,SEC23B,POMT1,AP4B1,GABRA1,GABRG2,GAD1,ZMYND11,CPLX1,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,NFU1,GFER,MMADHC,GK,GLI2,GNAO1,GP1BB,PCLO,GRIK2,GRM1,CIT,AP4S1,MAN1B1,HNRNPK,KCNB1,KCNH1,KCNJ10,KCNJ11,KCNQ2,KIF2A,KIF5C,LAMP2,LIG4,MAG,MEIS2,MID1,MTR,MYO5A,MYO7A,NF1,DDR2,OCRL,OGDH,OPHN1,PAH,PAX6,PC,PDE4D,PLP1,PSAT1,MAGEL2,POLG,PPM1B,PRODH,CNNM2,PTCH1,PEX2,PEX5,QDPR,RET,SETD5,SCN2A,SCN8A,FOXRED1,PUF60,PEX26,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNAP25,SNRPN,MYT1L,SOX2,SOX3,SOX10,SOX11,ZNF423,SPART,POGZ,STXBP1,ABCC8,DDHD2,CAMTA1,SATB2,RPGRIP1L,WASHC4,SZT2,AP4E1,KAT6B,TSC1,TSC2,TUBB2A,HIRA,UBE3A,VLDLR,NSD2,XRCC4,ZIC2,MKRN3,KAT6A,AAAS" Disease C1864897 Cognitive delay DisGeNET Curated 7.53E-08 9.28E-04 2.06E-05 2.06E-04 156 614 "ABAT,ACADM,RBM10,ARID1A,ADAR,PLA2G6,AMPD2,ANK1,KCNAB2,APP,CASK,ARSE,ASPA,ATP1A3,ALDH7A1,KIF1A,BBS2,BCS1L,ST3GAL5,CACNA1D,AP4M1,LARGE1,ADGRG1,COG1,COL11A2,CPS1,PREPL,SH2B1,SEC24C,HDAC4,KIAA0586,ZBTB24,ARNT2,DLG3,MED12,CDON,SLC12A6,GNE,USH1C,EDNRB,EEF1A2,EMX2,ERCC2,APC2,EYA1,TUBB3,FKTN,FGFR1,FGFR3,MAD2L2,SEC23B,POMT1,AP4B1,GABRA1,GABRG2,GAD1,ZMYND11,CPLX1,GATM,GCK,TUBGCP4,TUBA8,SRCAP,AHDC1,NFU1,GFER,MMADHC,GK,GLI2,GNAO1,GP1BB,PCLO,GRIK2,GRM1,CIT,AP4S1,MAN1B1,HNRNPK,KCNB1,KCNH1,KCNJ10,KCNJ11,KCNQ2,KIF2A,KIF5C,LAMP2,LIG4,MAG,MEIS2,MID1,MTR,MYO5A,MYO7A,NF1,DDR2,OCRL,OGDH,OPHN1,PAH,PAX6,PC,PDE4D,PLP1,PSAT1,MAGEL2,POLG,PPM1B,PRODH,CNNM2,PTCH1,PEX2,PEX5,QDPR,RET,SETD5,SCN2A,SCN8A,FOXRED1,PUF60,PEX26,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SNAP25,SNRPN,MYT1L,SOX2,SOX3,SOX10,SOX11,ZNF423,SPART,POGZ,STXBP1,ABCC8,DDHD2,CAMTA1,SATB2,RPGRIP1L,WASHC4,SZT2,AP4E1,KAT6B,TSC1,TSC2,TUBB2A,HIRA,UBE3A,VLDLR,NSD2,XRCC4,ZIC2,MKRN3,KAT6A,AAAS" Disease C0002736 Amyotrophic Lateral Sclerosis DisGeNET Curated 1.36E-07 1.68E-03 3.65E-05 3.65E-04 158 629 "SERPINA3,ADAR,ADARB2,SLC12A5,CDC7,ALAD,AMPH,MAP4K3,APAF1,ALS2,APP,AQP4,ASPA,RIPK1,BBS2,PROM1,CDK5R1,ARHGEF7,NIPA1,CFAP410,CALB1,CAST,INA,P2RX6,CHGA,CHGB,CNR1,GDA,CRYM,CS,OSBPL3,CST3,RIMS2,CX3CR1,CYBB,ARHGAP24,HDAC4,MATR3,DCTN1,DDX46,DNM2,DPP6,EDN1,ATL1,OPTN,CELSR3,APH1A,EGFR,EIF4G2,BSCL2,DCTN4,OLIG2,ERBB4,PTK2B,FCGR3A,CHL1,GAP43,ATP8A2,GART,MSTN,GFAP,GFRA1,PPARGC1A,GJB1,TTBK1,HPGDS,TPPP,GRIA1,GRIA2,GRIK1,GRM2,GRM3,GRM5,PSIP1,HNRNPK,IGF1,KCNJ10,KCNK2,STMN1,LIG4,MAOB,MAPT,SYT9,KITLG,MOBP,MYH6,MYO6,NCAM1,NEFM,NEFH,NEK1,NFE2L2,NOS1,P2RX7,P2RY1,TREM2,PCSK2,XRN1,PLCD1,PTPA,MAPK3,MAPK8,MAPK9,PRPH,PTPRN,OXR1,RASGRF1,RET,RNASE1,FBXW7,LRRK2,ATAT1,CLIP1,ATXN1,ATXN2,SFPQ,SGK1,FNDC3A,SLC1A2,SLC6A1,SIRT2,CCDC88A,SLC12A2,SLC12A4,SNAP25,SNRPN,WDTC1,HECW1,KIF1B,SST,TTBK2,SYP,SYT1,TAC1,TACR1,MGRN1,SIRT1,TLR4,TNFRSF1B,CABIN1,TNS1,PRMT8,SMUG1,TRPM2,GORASP1,VGF,VSNL1,RBFOX3,CLIP2,SLC30A3,WNK1,SLC17A6,NELFE,RTN4,CAMK1G,NUP214,NLRP3,JPH3" Disease C0454644 Delayed speech and language development DisGeNET Curated 1.99E-07 2.46E-03 4.92E-05 4.92E-04 43 116 "PLA2G6,ASPA,ALDH7A1,BTK,AIFM1,TPP1,NIPBL,CP,SH2B1,DLG3,AASS,BSCL2,FKTN,FGFR1,AFF2,AP4B1,ZMYND11,GATM,KCNJ10,L1CAM,MEF2C,MEIS2,NF1,OPHN1,PAK3,PDE4D,PIK3R1,PLP1,MAGEL2,SETD5,SLC6A8,SNRPN,MYT1L,SOX5,IQSEC2,CAMTA1,SATB2,KAT6B,UBE3A,VLDLR,XRCC4,MKRN3,FTSJ1" Disease C0233715 Speech impairment DisGeNET Curated 1.99E-07 2.46E-03 4.92E-05 4.92E-04 43 116 "PLA2G6,ASPA,ALDH7A1,BTK,AIFM1,TPP1,NIPBL,CP,SH2B1,DLG3,AASS,BSCL2,FKTN,FGFR1,AFF2,AP4B1,ZMYND11,GATM,KCNJ10,L1CAM,MEF2C,MEIS2,NF1,OPHN1,PAK3,PDE4D,PIK3R1,PLP1,MAGEL2,SETD5,SLC6A8,SNRPN,MYT1L,SOX5,IQSEC2,CAMTA1,SATB2,KAT6B,UBE3A,VLDLR,XRCC4,MKRN3,FTSJ1" Disease C0023012 Language Delay DisGeNET Curated 1.99E-07 2.46E-03 4.92E-05 4.92E-04 43 116 "PLA2G6,ASPA,ALDH7A1,BTK,AIFM1,TPP1,NIPBL,CP,SH2B1,DLG3,AASS,BSCL2,FKTN,FGFR1,AFF2,AP4B1,ZMYND11,GATM,KCNJ10,L1CAM,MEF2C,MEIS2,NF1,OPHN1,PAK3,PDE4D,PIK3R1,PLP1,MAGEL2,SETD5,SLC6A8,SNRPN,MYT1L,SOX5,IQSEC2,CAMTA1,SATB2,KAT6B,UBE3A,VLDLR,XRCC4,MKRN3,FTSJ1" Disease C0524528 Pervasive Development Disorder DisGeNET BeFree 1.99E-07 2.46E-03 4.92E-05 4.92E-04 43 116 "ADORA2A,PTCHD1,NLGN4X,APC,CASK,MPDZ,CACNA1G,CD38,TAOK2,NRXN3,NRXN1,CNTNAP2,CTNND2,RAB39B,SHANK1,KMT5B,EN2,GPHN,AFF2,SRRM4,GFAP,KIRREL3,GPR37,GRM7,GRM8,IL1RAPL1,HTR2A,MAPT,NEXMIF,NOS1,ZNF713,OXTR,PAX6,NLGN3,RELN,SHANK2,MBD5,SYN1,TCF4,TRIO,XPO1,CBLN2,GAN" Disease C1535926 Neurodevelopmental Disorders DisGeNET Curated 2.24E-07 2.76E-03 5.42E-05 5.42E-04 47 132 "ADCYAP1R1,FZD9,PTCHD1,HACE1,ANK3,CNTNAP1,ATP1A3,CACNA1A,CD38,NRXN1,SH2B1,CNTNAP2,DLG2,DYRK1A,EEF1A2,EIF4G1,ELN,VPS13B,GPHN,FOXG1,NRG3,GABRB3,DISC1,NTNG2,LRRTM1,KCNA2,KCNB1,L1CAM,MEF2C,RELN,FBXW7,MEG3,SCN8A,NTNG1,SHANK2,SMARCA4,MBD5,SNRPN,SOX11,POGZ,STXBP1,ASTN2,SATB2,TCF7L2,TSC1,TSC2,UBE3A" Disease C0013421 Dystonia DisGeNET Curated 2.76E-07 3.40E-03 6.52E-05 6.51E-04 66 211 "ADAR,ADCY5,PLA2G6,LRRC7,SEMA6A,ALS2,APP,ATM,ATP1A2,ATP1A3,BCS1L,DST,SYNJ1,SGCE,CACNA1A,CACNA1B,CHRNA4,FBXO7,PNKD,SNCAIP,PNPLA8,RIMS2,DBT,DNAJC6,DRD1,BSCL2,TUBB3,TUBB4A,FOXG1,TPK1,AP4B1,MMADHC,GNAL,GRM5,GSN,HPCA,ATCAY,KCNQ2,PLP1,FA2H,PRKCG,APTX,QDPR,RBBP6,PRRT2,KCTD17,LRRK2,ATXN1,ATXN2,SCN8A,SCP2,SLC30A10,FOXRED1,ARX,SLC6A8,SLC20A2,SNCA,VAMP1,VPS13A,MCF2L,ALG1,DMXL2,SLC19A3,TRIO,NELFE,AAAS" Disease C0393593 Dystonia Disorders DisGeNET Curated 2.80E-07 3.45E-03 6.52E-05 6.51E-04 45 125 "ADAR,ADCY5,PLA2G6,LRRC7,SEMA6A,ALS2,APP,ATM,ATP1A3,DST,SGCE,CACNA1A,CACNA1B,PNKD,RIMS2,DBT,DRD1,TUBB3,TUBB4A,GNAL,GRM5,GSN,HPCA,ATCAY,FA2H,PRKCG,APTX,RBBP6,PRRT2,KCTD17,LRRK2,ATXN1,ATXN2,SCN8A,SCP2,SLC30A10,ARX,SLC6A8,SLC20A2,MCF2L,ALG1,SLC19A3,TRIO,NELFE,AAAS" Disease C0234162 Cerebellar Dysmetria DisGeNET Curated 3.33E-07 4.11E-03 7.61E-05 7.61E-04 26 56 "PLA2G6,ATP1A3,KIF1A,PNPLA8,SACS,ELN,GRM1,MAG,OPHN1,PDYN,PLP1,PPP2R2B,PRKCG,PEX2,ATXN1,ATXN2,ATXN7,SPART,CAMTA1,SYNE1,PIK3R5,TTPA,UCHL1,VLDLR,CLIP2,XRCC4" Disease C3887898 Infantile Spasm DisGeNET Curated 3.45E-07 4.25E-03 7.73E-05 7.73E-04 20 37 "KCNAB2,KIF1A,RIMS2,MAGI2,DNM1,FOXG1,GABRA1,GABRB3,GRIN1,NR3C1,KCNQ2,ATXN2,SCN2A,ARX,SPTAN1,STXBP1,PLCB1,TSC1,TSC2,NELFE" Disease C0037769 West Syndrome DisGeNET Curated 5.14E-07 6.33E-03 1.13E-04 1.13E-03 26 57 "KCNT1,KCNAB2,CACNA2D1,RIMS2,MAGI2,DNM1,FOXG1,GABRA1,GABRB3,GRIN1,NR3C1,KCNQ2,RASGRF1,PRRT2,ATXN2,SCN2A,SCN8A,ARX,ST3GAL3,WDTC1,SPTAN1,STXBP1,PLCB1,TSC1,TSC2,NELFE" Disease C0014556 "Epilepsy, Temporal Lobe" DisGeNET Curated 6.11E-07 7.54E-03 1.32E-04 1.32E-03 46 132 "SLC12A5,BIN1,AQP4,HCN2,CALM1,HAP1,LGI1,SLIT2,CNR1,CASP8AP2,GPHN,GABBR1,GABRA1,GABRA2,GABRB3,GLUL,GRIA2,GRIK1,GRIK2,GRIN1,GRM1,GRM2,GRM3,GRM5,HMGB1,HTR2A,KCND2,KCNJ10,KCNK2,KCNQ3,NFE2L2,NPY,HCN1,P2RX7,PDYN,ABCB1,RELN,SCN7A,SLC1A2,SLC6A9,SLC12A2,SOX2,SST,MAPK8IP3,VPS13A,TEK" Disease C0006012 Borderline Personality Disorder DisGeNET BeFree 7.12E-07 8.78E-03 1.51E-04 1.51E-03 40 109 "ANK3,APBA2,SYNJ1,CALB2,NRXN3,CLOCK,TENM4,ZNF804A,EGFR,ERBB4,EYA1,NRN1,GAD1,GAD2,DISC1,GNAS,MCHR1,GRIK2,NR3C1,HTR2A,KCNQ2,KCNQ3,MAOB,NINJ2,OXTR,P2RX7,PRIMA1,PBRM1,SCN4B,SCN8A,SLC1A2,SMARCA4,NPAS3,SST,TAC1,SIRT1,NPL,ETNPPL,LMAN2L,MPPE1" Disease C0751495 "Seizures, Focal" DisGeNET Curated 9.92E-07 1.22E-02 2.04E-04 2.04E-03 16 27 "SLC12A5,PCDH19,KCNT1,LGI1,CHRNA4,GABRG2,GRIN1,KCND3,KCNQ3,POLG,SCN2A,SCN8A,PLCB1,SYN1,CNTN2,SZT2" Disease C1321329 Slowed saccades DisGeNET Curated 9.94E-07 1.23E-02 2.04E-04 2.04E-03 10 12 "FBXO7,NOP56,PDYN,PEX2,ATXN1,ATXN2,ATXN7,VAMP1,ATP13A2,PIK3R5" Disease C0026650 Movement Disorders DisGeNET Curated 1.20E-06 1.48E-02 2.43E-04 2.43E-03 49 147 "ACHE,ADCY5,ALS2,PDE8B,ATP1A2,ATP1A3,ALDH7A1,KIF1A,SGCE,CACNA1A,LGI1,CNR1,CP,PNKD,DRD1,ATL1,PPP1R1B,FGF14,FOXG1,GAP43,GNAL,GRIN1,LINGO1,HNMT,HTR2A,KCNA1,MAPT,MTTP,MYO5A,OGDH,PAX6,PDYN,POLG,PEX2,PEX5,PRRT2,LRRK2,ATXN7,SCN8A,ASIC4,ARX,NTNG1,PEX26,SLC12A2,SNCA,TTBK2,STXBP1,ARC,GOPC" Disease C0030552 Paresis DisGeNET Curated 1.22E-06 1.51E-02 2.43E-04 2.43E-03 40 111 "ACHE,BIN1,ALS2,BCHE,CACNA1A,RIMS2,MATR3,DMD,DMPK,DNM2,GNE,EEF1A2,FSD1L,FKTN,FHL1,FLNC,GAA,IGF1,STMN1,MYH3,MYH7,NCAM1,NPTX2,PKM,PMP22,POLG,FSD1,GLDN,RYR1,SCN8A,SNRPN,KIF1B,ZC4H2,MTMR14,TPM1,TPM2,TPM3,ANO5,BEST1,NELFE" Disease C1457883 Aggressive reaction DisGeNET Curated 1.76E-06 2.17E-02 3.44E-04 3.44E-03 31 78 "DGCR6,PLA2G6,AMT,ANK3,CAST,SH2B1,DNM1,MED12,EEF1A2,AFF2,GABRB3,ZMYND11,GLDC,MAN1B1,MAPT,NDP,OCRL,PAH,TREM2,PAK3,MAPK3,MAPK10,PRODH,RBBP8,SLC6A8,MYT1L,VPS13A,SYN1,TCF4,SATB2,ATP13A2" Disease C0151889 Hyperreflexia DisGeNET Curated 2.09E-06 2.58E-02 4.03E-04 4.03E-03 63 209 "ABAT,PLA2G6,AMPD2,AMT,CASK,KIF1A,BCS1L,CA8,AP4M1,ADGRG1,FBXO7,CSF1R,RUBCN,MATR3,SACS,ATL1,BSCL2,ELN,GPHN,EYA1,REEP2,NOP56,AP4B1,GAD1,ATP8A2,GLDC,GLUL,PCLO,GRM1,CIT,AP4S1,KCNA1,KIF5A,L1CAM,OPA1,PAH,PDYN,PLP1,PPP2R2B,PRKCG,PEX2,PEX5,ATXN1,FOXRED1,PEX26,RAB3GAP1,CCDC88A,SLC20A2,SPTAN1,SPART,ABCC8,VAMP1,PLCB1,DDHD2,RPGRIP1L,ATP13A2,AP4E1,UBE3A,UCHL1,VLDLR,CLIP2,AAAS,GAN" Disease C0007758 Cerebellar Ataxia DisGeNET Curated 2.36E-06 2.90E-02 4.47E-04 4.47E-03 116 453 "ACHE,AK2,PLA2G6,SEMA6A,ALK,ANK1,ATM,ATP1A2,ATP1A3,ATP2B3,BCS1L,CACNA1G,CA8,CACNA1A,CACNB4,CALM1,KRIT1,AIFM1,SCARB1,LGI1,PPT2,TPP1,TBPL1,CP,CPS1,RGS6,RUBCN,KIAA0586,DBT,SACS,DLG4,ATN1,USH1C,EDNRB,BSCL2,ENO2,ERCC2,FGF14,SEC23B,NOP56,UFM1,TPK1,FYN,GAA,GABRA1,GABRG2,GALC,ATP8A2,GFAP,GJB1,GRM1,GRM5,ATCAY,KCNA1,KCNA2,KCNC2,KCND3,KCNJ10,KCNN3,MTTP,MYO5A,MYO7A,OGDH,OGG1,OPA1,OPHN1,PAX6,PDYN,PLP1,POLG,PPP2R2B,PRKCG,APTX,PEX2,PEX5,RAD17,UEVLD,ACER3,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,FOXRED1,PEX26,SLC6A1,SLC6A8,SNAP25,SNCA,SOX10,ZNF423,ARHGAP26,TTBK2,STXBP1,MLC1,ABCC8,VAMP1,VPS13A,CAMTA1,DMXL2,RPGRIP1L,SYNE1,PIK3R5,TRIO,TSC1,TTPA,UBE3A,UCHL1,VLDLR,NSD2,ZIC1,ZIC2,TUBA1A,GJC2,SNX14,AAAS" Disease C0026827 Muscle hypotonia DisGeNET Curated 2.69E-06 3.32E-02 5.03E-04 5.03E-03 141 575 "ABAT,DGCR6,ACADM,RBM10,ARID1A,ADCY6,PLA2G6,ALAD,AMT,ANK3,CNTNAP1,KCNAB2,ASCL1,ASPA,ALDH7A1,KIF1A,BCS1L,ST3GAL5,CA8,LARGE1,CFL2,NRXN1,COG1,CPS1,PREPL,SEC24C,PNPLA8,CTNND2,HDAC4,KIAA0586,DBT,ZEB2,DLG3,DMD,DNM1,DMPK,MED12,DNM2,DNM1L,EDNRB,EEF1A2,AASS,ELN,ERCC2,APC2,ACSL4,FKTN,FGFR3,FOXG1,POMT1,STAMBP,TPK1,GAA,GABRA1,CHL1,GABRG2,GALC,ATP8A2,AHDC1,MMADHC,GLDC,GLUL,GP1BB,GRM1,HBA1,HNRNPK,ITGA7,KCNB1,KCNH1,KCNJ10,KCNQ2,KCNQ3,LAMA2,LIFR,MAG,MEF2C,MTTP,MTR,MYO5A,NFIX,DDR2,OGDH,OPHN1,PAX6,PC,RETREG1,PLP1,PMP22,PMS2,POLG,PPM1B,KANSL1,PRODH,PTCH1,PEX2,PEX5,QDPR,RET,REV3L,RPE65,RYR1,ATXN1,ATXN2,SCN2A,SCN8A,FOXRED1,PEX26,SLC6A8,RAB3GAP1,SMARCA4,SMARCE1,SOX2,SOX5,SOX10,SOX11,ZNF423,SPTAN1,KANK1,STXBP1,VPS13A,TCF4,SATB2,RPGRIP1L,SZT2,CRB1,THRA,TK2,KAT6B,TPM2,TPM3,TRPS1,KCNE5,TUBB2A,HIRA,UBE3A,VLDLR,CLIP2,NSD2,ZIC1,TUBA1A,KAT6A" Disease C0037772 Spastic Paraplegia DisGeNET Curated 2.98E-06 3.67E-02 5.48E-04 5.48E-03 34 91 "AMPD2,KIF1A,NIPA1,CACNA1D,CALM1,CAPN3,KRIT1,AP4M1,SACS,ATN1,ATL1,BSCL2,REEP2,AP4B1,GAA,GALC,GFAP,NFU1,AP4S1,KIF5A,L1CAM,NRCAM,PLP1,FA2H,PTHLH,SPART,STXBP1,VAMP1,DDHD2,AP4E1,DDHD1,REEP1,GJC2,GAN" Disease C2931919 X-linked infantile spasm syndrome DisGeNET BeFree 3.64E-06 4.49E-02 6.60E-04 6.60E-03 10 13 "ATP1A3,GABRB3,GNAO1,KCNQ2,HCN1,ARX,SPTAN1,STXBP1,PLCB1,KCNAB1" Disease C2267233 Neonatal Hypotonia DisGeNET Curated 4.21E-06 5.19E-02 7.52E-04 7.52E-03 27 66 "BIN1,DST,AP4M1,CNTN1,SH2B1,MED12,SLC12A6,EEF1A2,FOXG1,TBR1,AP4B1,TUBA8,PCLO,ITGA7,MYH7,OCRL,MAGEL2,PEX2,RYR1,PEX26,SLC6A8,SOX10,CAMTA1,AP4E1,TPM2,TPM3,KAT6A" Disease C0014306 Enophthalmos DisGeNET Curated 5.20E-06 6.41E-02 9.03E-04 9.03E-03 26 63 "KCNAB2,CHN1,HDAC4,ARNT2,DYRK1A,DNM1L,EEF1A2,ERCC2,SEPT9,SRCAP,KCNQ2,KCNQ3,MEIS2,MYH3,NDP,OCRL,OPHN1,PIK3R1,PLEC,SCN2A,SCN8A,RAB3GAP1,TBX15,TCF4,UBE3A,XRCC4" Disease C0423224 Sunken eyes DisGeNET Curated 5.20E-06 6.41E-02 9.03E-04 9.03E-03 26 63 "KCNAB2,CHN1,HDAC4,ARNT2,DYRK1A,DNM1L,EEF1A2,ERCC2,SEPT9,SRCAP,KCNQ2,KCNQ3,MEIS2,MYH3,NDP,OCRL,OPHN1,PIK3R1,PLEC,SCN2A,SCN8A,RAB3GAP1,TBX15,TCF4,UBE3A,XRCC4" Disease C0001807 Aggressive behavior DisGeNET Curated 7.15E-06 8.81E-02 1.22E-03 1.22E-02 29 75 "DGCR6,PLA2G6,AMT,ANK3,SH2B1,DNM1,MED12,EEF1A2,AFF2,GABRB3,ZMYND11,GLDC,MAN1B1,MAPT,NDP,OCRL,PAH,TREM2,PAK3,MAPK10,PRODH,RBBP8,SLC6A8,MYT1L,VPS13A,SYN1,TCF4,SATB2,ATP13A2" Disease C0007760 Cerebellar Diseases DisGeNET Curated 8.40E-06 1.04E-01 1.42E-03 1.42E-02 19 40 "CASK,ATM,SGCE,CACNA1A,ABCA8,ZIC4,FLNC,TPPP,GRM1,ATCAY,TMEM240,KCNA1,NOS1,PDYN,PPP2R2B,PRKCG,ATXN7,RPGRIP1L,ZIC1" Disease C0025149 Medulloblastoma DisGeNET Curated 9.12E-06 1.12E-01 1.52E-03 1.52E-02 135 558 "ABR,ACHE,AXIN2,APC,USP37,ASCL1,ASPH,PTCH2,DYNLL1,NRP2,PROM1,BTRC,CALB1,CALM1,NEURL1,DIS3L,SOCS6,SLIT2,KMT2C,COL9A1,COL9A2,COL9A3,ZNF521,AKAP12,CRMP1,CSF1R,VCAN,BOC,HDAC9,ARHGAP24,DAPK1,DDX46,DNM2,EEF1D,EGFR,EN2,OLIG2,EPHB1,ERBB2,ERBB4,EYA1,F3,PTK2B,TUBB3,SCML2,DLC1,STRADA,KAT8,FOXG1,FOXM1,KHDRBS3,DKK3,GABRA5,DNER,GFAP,HPGDS,GLI2,GNAS,GRIA1,GSN,KIF3A,PSIP1,ARHGAP36,HMGB1,HSP90AA1,IGF1,IL6ST,INSM1,KCNA1,KIT,STMN1,LIFR,LIG4,MAP2,MEIS1,KCTD6,MSI1,MXI1,MYCN,NEUROD1,NEUROD2,NHLH1,NNAT,NTRK3,PAX6,PDGFRA,CDK14,ABCB1,PIK3CD,PKM,PLEC,PMS2,MED1,MAPK3,MAPK7,MAPK8,PTCH1,PID1,RPS20,WLS,S100B,SCN8A,SCG5,SLC1A2,KDM4B,WDTC1,SOX2,SOX11,KDM4C,UNC5B,SST,SSTR2,SYP,SYT1,TF,DICER1,SIRT1,HHIP,TNFRSF1B,TNR,TPM3,TRH,TSC1,TSC2,CADM1,GORASP1,VAV1,RICTOR,ZIC1,ZIC2,FSTL5,WNK1,PRDM2,EPM2A,KAT6A" Disease C1843921 Postural instability DisGeNET Curated 9.36E-06 1.15E-01 1.54E-03 1.54E-02 12 19 "PLA2G6,ATP1A3,SYNJ1,FBXO7,SNCAIP,CSF1R,DNAJC6,ATXN2,SLC30A10,SLC20A2,SNCA,ATP13A2" Disease C0424323 Physical aggression DisGeNET Curated 9.68E-06 1.19E-01 1.57E-03 1.57E-02 29 76 "DGCR6,PLA2G6,AMT,ANK3,SH2B1,DNM1,MED12,EEF1A2,AFF2,GABRB3,ZMYND11,GLDC,MAN1B1,MAPT,NDP,OCRL,PAH,TREM2,PAK3,MAPK10,PRODH,RBBP8,SLC6A8,MYT1L,VPS13A,SYN1,TCF4,SATB2,ATP13A2" Disease C0424688 Small head DisGeNET Curated 9.91E-06 1.22E-01 1.59E-03 1.59E-02 97 375 "DGCR6,ARID1A,AGT,AMPD2,ANK1,KCNAB2,CASK,ARSE,KIF1A,BLM,AP4M1,LARGE1,NIPBL,RTTN,CTNND2,HDAC4,ARNT2,CDON,SLC12A6,DPP6,DYRK1A,DNM1L,WDPCP,EEF1A2,ELN,ERCC2,TUBB3,FKTN,FGFR1,FGFR3,MAD2L2,FOXG1,POMT1,AP4B1,CHL1,GAD1,CPLX1,TUBGCP4,TUBA8,GLI2,CIT,AP4S1,HBA1,IGF1,RBPJ,KCNJ11,KIF2A,KIF5C,L1CAM,LIG4,MEIS2,KITLG,MITF,MYCN,MYH3,NF1,PAH,PAK3,PAX6,PLP1,PSAT1,POLG,MASP1,RELN,CNNM2,PEX2,PEX5,QDPR,RBBP8,SALL1,SBF1,SCN8A,PUF60,NTNG1,PEX26,SLC6A8,RAB3GAP1,SLC20A2,SMARCA4,SMARCE1,SOX2,SOX10,SOX11,ABCC8,TCF4,SATB2,RPGRIP1L,AP4E1,KAT6B,CLIP2,NSD2,XRCC4,ZIC2,ZBTB16,TUBA1A,KAT6A,AAAS" Disease C0037773 "Spastic Paraplegia, Hereditary" DisGeNET Curated 1.03E-05 1.27E-01 1.62E-03 1.62E-02 26 65 "PLA2G6,ALS2,APP,NIPA1,CACNA1A,ATL1,REEP2,IBA57,KIF5A,KIF5C,L1CAM,ZFYVE27,PLP1,FA2H,RTN1,ATXN2,ATXN7,SLC1A2,IFT122,KIF1B,SPART,DDHD2,AP4E1,REEP1,GJC2,AAAS" Disease C0234366 ataxic DisGeNET BeFree 1.06E-05 1.31E-01 1.65E-03 1.65E-02 17 34 "ATM,CACNA1A,SACS,GAA,GRM1,ATCAY,IGFBP1,KCNA2,POLG,APTX,ATXN1,ATXN2,ATXN7,SLN,TTPA,UCHL1,VLDLR" Disease C0026106 Mild Mental Retardation DisGeNET Curated 1.13E-05 1.39E-01 1.74E-03 1.74E-02 39 116 "BIN1,ATP2A2,CA8,CHRNA4,CLCN4,ABCG2,SEC24C,CTNND2,DLG3,DMD,SHANK1,ABCC9,AASS,BSCL2,EYA1,FGF14,AFF2,POMT1,ZMYND11,DISC1,GP1BB,IL1RAPL1,IGF1,NF1,PMP22,MASP1,STK32B,ARX,SLC6A8,SHANK2,SOX3,CDK19,SPART,MLC1,CAMTA1,TRIO,PDSS1,HIRA,FTSJ1" Disease C0751122 Infantile Severe Myoclonic Epilepsy DisGeNET Curated 1.19E-05 1.47E-01 1.81E-03 1.81E-02 14 25 "ADRA1D,PCDH19,CACNA1A,CACNB4,EPHA5,GPHN,GABRA1,GABRB3,GABRG2,POLG,PRRT2,SCN2A,SCN8A,STXBP1" Disease C0728829 Congenital pes cavus DisGeNET Curated 1.45E-05 1.79E-01 2.19E-03 2.19E-02 32 89 "ATP1A3,SYNJ1,AIFM1,DCAF8,DNAJC6,SACS,DNM2,ATL1,BSCL2,FGFR1,GJB1,KIF5A,L1CAM,LAMP2,MYH7,PLP1,PMP22,POLG,APTX,PEX5,RET,SLC6A8,SOX10,KIF1B,IQSEC2,SPART,VAMP1,VPS13A,TRIM2,TPM3,TTPA,GAN" Disease C1854301 Motor delay DisGeNET Curated 1.58E-05 1.94E-01 2.31E-03 2.31E-02 47 151 "BIN1,PTCH2,MTMR2,LARGE1,SMARCAL1,RUBCN,ZEB2,ZBTB24,MED12,DNM2,SLC12A6,USH1C,ATL1,SPEG,FKTN,FGFR3,FOXG1,POMT1,GCK,GHR,GJB1,IGF1,ITGA7,KCNJ11,LAMA2,MEF2C,MYO7A,NFIX,PLEC,PMP22,MAGEL2,PTCH1,REV3L,RYR1,SLC6A8,SNRPN,SOX5,SPART,MLC1,ABCC8,TCF4,DMXL2,TPM2,TPM3,UBE3A,MKRN3,TUBA1A" Disease C4020874 No development of motor milestones DisGeNET Curated 1.58E-05 1.94E-01 2.31E-03 2.31E-02 47 151 "BIN1,PTCH2,MTMR2,LARGE1,SMARCAL1,RUBCN,ZEB2,ZBTB24,MED12,DNM2,SLC12A6,USH1C,ATL1,SPEG,FKTN,FGFR3,FOXG1,POMT1,GCK,GHR,GJB1,IGF1,ITGA7,KCNJ11,LAMA2,MEF2C,MYO7A,NFIX,PLEC,PMP22,MAGEL2,PTCH1,REV3L,RYR1,SLC6A8,SNRPN,SOX5,SPART,MLC1,ABCC8,TCF4,DMXL2,TPM2,TPM3,UBE3A,MKRN3,TUBA1A" Disease C0242422 Parkinsonian Disorders DisGeNET Curated 1.73E-05 2.13E-01 2.51E-03 2.51E-02 57 195 "ACHE,PLA2G6,APP,ATP1A3,SYNJ1,RUNX1T1,CDR1,CHM,FBXO7,CP,SNCAIP,CSF1R,RIMS2,DNAJC6,DCTN1,RAB39B,EEF1A2,EIF4G1,PPP1R1B,OGA,FYN,GAD2,GFAP,GLUL,CIT,PACRG,MAOB,MAPT,SLC11A2,OPA1,TREM2,PDYN,PENK,MAPKAP1,POLG,PPP2R2B,PRKCG,VPS13C,FBXW7,LRRK2,ATXN2,ATXN7,SLC30A10,SLC20A2,SNCB,SNCA,SPP1,STXBP1,VPS13A,TAC1,MCF2L,ATP13A2,ZFPM2,TNS1,SMUG1,UCHL1,NELFE" Disease C0027066 Myoclonus DisGeNET Curated 1.89E-05 2.32E-01 2.70E-03 2.70E-02 36 106 "PCDH19,AMT,APP,ATM,ST3GAL5,SGCE,CACNA1B,TPP1,DNM1,BSCL2,GPHN,STAMBP,GAA,GABRB3,GLDC,KCNA2,KCNC1,KCND3,KCNQ2,KCNQ3,MAPT,TREM2,SERPINI1,PLXNB1,POLG,PRKCG,MAPK10,QDPR,ATXN2,SCN2A,SCN8A,SNCA,CNTN2,ATP13A2,EPM2A,AAAS" Disease C1852197 MAJOR AFFECTIVE DISORDER 1 DisGeNET Curated 2.21E-05 2.72E-01 3.05E-03 3.05E-02 28 75 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,MAGI2,DMPK,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,MLC1,TACR1,TCF4,CUX2,NPL" Disease C2700438 MAJOR AFFECTIVE DISORDER 7 DisGeNET Curated 2.23E-05 2.75E-01 3.05E-03 3.05E-02 24 60 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,TCF4,CUX2,NPL" Disease C2700439 MAJOR AFFECTIVE DISORDER 8 DisGeNET Curated 2.23E-05 2.75E-01 3.05E-03 3.05E-02 24 60 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,TCF4,CUX2,NPL" Disease C2700440 MAJOR AFFECTIVE DISORDER 9 DisGeNET Curated 2.23E-05 2.75E-01 3.05E-03 3.05E-02 24 60 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,TCF4,CUX2,NPL" Disease C0026838 Muscle Spasticity DisGeNET Curated 2.33E-05 2.87E-01 3.15E-03 3.15E-02 69 251 "ADAR,PLA2G6,AMPD2,ANK3,ALS2,CASK,ASPA,ATM,BCS1L,NIPA1,PPT2,CNR1,CSF1R,PNPLA8,MATR3,DCTN1,SACS,ARNT2,ATL1,OPTN,BSCL2,ELN,ERBB4,ERCC2,TUBB3,FOXG1,TPK1,GAA,GFAP,PPARGC1A,GLRB,PCLO,GRIA1,GRIA2,GRIK2,GRIK3,GRM2,GRM7,HTR2A,L1CAM,NEFH,OPA1,OPHN1,TREM2,RETREG1,PLCD1,PRPH,PEX2,PEX5,ATXN1,ATXN2,ATXN7,FOXRED1,NTNG1,PEX26,SLC6A8,RAB3GAP1,IFT122,SOX10,MLC1,ABCC8,PLCB1,RPGRIP1L,ATP13A2,AMACR,CLIP2,REEP1,GJC2,GAN" Disease C0344482 Hypoplasia of corpus callosum DisGeNET Curated 2.42E-05 2.98E-01 3.24E-03 3.24E-02 35 103 "AMPD2,AP4M1,LARGE1,ZEB2,ARNT2,TUBB3,FKTN,FGFR1,FGFR3,FOXG1,POMT1,STAMBP,AP4B1,AHDC1,GLUL,GNAO1,PCLO,KIF2A,KIF5C,L1CAM,MEF2C,TREM2,PAX6,GPSM2,ASRGL1,SLC6A8,RAB3GAP1,SOX2,SPTAN1,POGZ,STXBP1,DDHD2,TCF4,TUBB2A,TUBA1A" Disease C0020179 Huntington Disease DisGeNET Curated 2.56E-05 3.16E-01 3.40E-03 3.39E-02 142 604 "KCNH8,ASIC1,ACHE,KDM5D,ADD1,ADORA2A,HACE1,SEMA6A,APAF1,APP,ATM,ATP2A2,ALDH7A1,C5,BTRC,CACNA1A,CALB1,CALB2,CALM1,HAP1,CBS,AIFM1,CHRM1,CNR1,CNTN1,RIMS2,CYBB,HDAC9,HDAC4,DLG3,DLG4,GRIN3A,DMD,DPP6,DPYSL2,DRD1,RCAN1,DNAJB6,DNM1L,EDNRA,EEF1A2,OPTN,DCTN4,EPHB1,APC2,PRMT5,PPP1R1B,FGF13,FGFR3,IP6K2,FOXO3,SORBS1,NSG1,GAD2,ATP8A2,CPLX2,GFAP,PPARGC1A,TCERG1,HPGDS,GRIK2,GRIK5,GRM2,GRM5,PTPN5,PSIP1,HPCA,ZDHHC15,HP,HSP90AA1,IGF1,MAOB,MAPT,KITLG,MT1M,NCAM1,NEUROD1,NFE2L2,NNAT,NPY,NTRK2,OGG1,P2RX7,PDE4A,PDE1B,PENK,ABCB1,PIK3CD,PSAT1,PACSIN1,PKN2,MAPK8,MAPK10,BDNF-AS,PTPN13,TUG1,ATG16L1,RET,FBXW7,TUNAR,RXRA,ATXN1,ATXN2,ATXN7,SH3GL3,SLC1A2,SLC1A3,SLC1A6,RPH3A,SIRT2,SLC9A5,ATF7IP,SLN,SNAP25,SNCA,WDTC1,SST,ACSBG1,VPS13A,SYN1,SYN2,TAC1,TAL1,CRTC1,SIRT1,ENHO,TNFRSF1B,RASD2,CDK20,SMUG1,TRPC1,TSC1,UBC,UBE3A,UCHL1,RBFOX3,PCBP4,NELFE,MARCH8,NUP214,NLRP3,JPH3" Disease C1970943 MAJOR AFFECTIVE DISORDER 4 DisGeNET Curated 2.80E-05 3.45E-01 3.64E-03 3.64E-02 27 72 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,MAGI2,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,MLC1,TACR1,TCF4,CUX2,NPL" Disease C1970945 MAJOR AFFECTIVE DISORDER 6 DisGeNET Curated 2.80E-05 3.45E-01 3.64E-03 3.64E-02 27 72 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,MAGI2,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PRKCZ,PBRM1,S100B,MLC1,TACR1,TCF4,CUX2,NPL" Disease C0006111 Brain Diseases DisGeNET Curated 2.90E-05 3.58E-01 3.73E-03 3.73E-02 68 248 "ADORA2A,NLGN4X,ALK,APP,CASK,ATP1A3,BCS1L,CDK5R1,AIFM1,LGI1,NRXN3,NRXN1,ABCG2,CP,CLOCK,CNTNAP2,DLG3,DSCAM,ABCC9,EDN1,BSCL2,DCTN4,ERBB4,FOXG1,STAMBP,TPK1,DISC1,GFAP,NFU1,GNAO1,GPT2,GRIN1,HMGB1,IBA57,KCNQ2,MAPT,OGG1,TREM2,ABCB1,NLGN3,SERPINI1,NALCN,PIK3CD,POLG,MAPK10,RELN,PTHLH,ZC3H14,S100B,SARS,SCN2A,SCN8A,ARX,SNCA,IQSEC2,LMO3,SST,STXBP1,SZT2,SLC19A3,SIRT1,TK2,TLR4,TSC1,TSC2,RBFOX3,MFF,NUP214" Disease C0349204 Nonorganic psychosis DisGeNET Curated 3.05E-05 3.76E-01 3.88E-03 3.88E-02 62 221 "SERPINA3,KIDINS220,PLA2G6,SEMA6A,ANK3,ARNTL,ARHGEF7,PICK1,TENM4,CSNK1E,ZNF804A,DLX1,MED12,SHANK1,DPYSL2,DRD1,DRP2,OLIG2,ERBB4,RTN3,PPP1R1B,FGFR3,SMC2,B3GAT1,GABRA1,GABRG2,GAD1,DISC1,GHR,PCDH11X,GRIK4,NR3C1,GRM2,GRM3,GRM5,HTR2A,HTR5A,KCNH2,MAPT,NPY,NRGN,PAK3,ABCB1,PPP3CC,RELN,RGS4,PBRM1,ALG9,SAFB,SLC6A9,SEPHS1,TET1,SNCA,SP4,NPAS3,WWC1,TCF4,NPL,PDSS1,TRPM2,FZD3,PAK5" Disease C0494463 "Alzheimer Disease, Late Onset" DisGeNET BeFree 3.31E-05 4.08E-01 4.16E-03 4.16E-02 59 208 "SERPINA3,SORCS1,AMPH,BIN1,ANK3,APBB2,APOC1,APP,ARRB2,MARK4,BCHE,CH25H,NRXN1,CLU,SLC25A27,CST3,ST18,DAPK1,NTM,DNM2,DRD1,DYRK1A,ELAVL2,ERBB4,APC2,PTK2B,FYN,SIGLEC8,CYP46A1,GFAP,PPARGC1A,HPGDS,PCDH11X,HMGCR,HTR2A,IGF1,LRRTM3,MAPT,CD200,CTNNA3,C10orf105,OLR1,TREM2,ABCB1,PIK3R1,RELN,CNTLN,ZCWPW1,ATXN1,SLC8A1,TET1,STOX1,DNMBP,WWC1,SIRT1,TLR4,SMUG1,VLDLR,NLRP3" Disease C0266449 Congenital anomaly of brain DisGeNET BeFree 3.63E-05 4.48E-01 4.52E-03 4.52E-02 18 40 "CASK,ADGRG1,DLG3,EMX2,KIRREL3,GLUL,ZIC5,TUBB2B,L1CAM,GPSM2,RELN,CNNM2,ARX,CRTC1,TSC1,ANO5,ZIC2,TUBA1A" Disease C1142166 Brugada Syndrome (disorder) DisGeNET Curated 3.69E-05 4.55E-01 4.55E-03 4.55E-02 20 47 "KCNT1,CACNA2D1,CACNB2,CALM1,NOS1AP,ATN1,FGF11,FGF12,FGF14,KCND2,KCND3,KCNH2,KCNK1,MYH7,KCNIP2,SCN2B,SCN4B,SCN3B,HEY2,KCNE5" Disease C0740279 Atrophy of cerebellum DisGeNET Curated 3.81E-05 4.70E-01 4.65E-03 4.65E-02 41 130 "PLA2G6,KIF1A,BCS1L,CACNA1A,AP4M1,TUBB4A,NOP56,ATP8A2,PCLO,GRM1,KCND3,KCNJ10,KCNN3,MAPT,MYH3,OPA1,PDYN,POLG,PPP2R2B,PRKCG,APTX,PEX2,ATXN1,ATXN2,ATXN7,SCN2A,SCN8A,FOXRED1,CCDC88A,EMC1,SPTAN1,SPART,SYNE1,AP4E1,PIK3R5,TRPC3,UCHL1,VLDLR,ZIC1,REEP1,SNX14" Disease C0040485 Torticollis DisGeNET Curated 3.89E-05 4.80E-01 4.70E-03 4.70E-02 12 21 "ATP1A3,SGCE,CACNA1A,CACNA1B,CP,PNKD,DNM2,GNAL,HPCA,PRRT2,SCP2,ATP13A2" Disease C0011168 Deglutition Disorders DisGeNET Curated 5.73E-05 7.07E-01 6.80E-03 6.80E-02 44 145 "PLA2G6,KCNAB2,APP,PDE8B,ASPA,ATP1A3,CACNA1A,PNKD,SNCAIP,MATR3,DMPK,DNAJB6,OPTN,MEGF10,GAA,GJB1,GUCY1A1,HPCA,KCND3,KIT,LIFR,MAPT,MID1,MYH7,NF1,PDGFRA,PLEC,PLP1,POLG,PRKCG,QDPR,REV3L,RYR1,ATXN1,ATXN2,ATXN7,FERMT1,SNCA,VAMP1,VPS13A,DDHD2,KAT6B,TPM2,TPM3" Disease C0011265 Presenile dementia DisGeNET BeFree 5.74E-05 7.08E-01 6.80E-03 6.80E-02 81 314 "SERPINA3,ACHE,PLA2G6,ALK,BIN1,APOC1,APP,BCHE,SYNJ1,RUNX1T1,CD38,CDR1,CHM,CHRNA4,TAOK2,CLU,CP,SNCAIP,CSF1R,CST3,PLXNA4,DCTN1,DNM2,ATN1,DSCAM,DYRK1A,SEZ6L2,EEF1A2,EIF4G1,GAP43,GFAP,PPARGC1A,GLS,NR3C1,WIF1,HTR2A,IGF1,IL6R,MAPT,MEF2C,NF1,NINJ2,NOVA2,NTRK2,OPA1,TREM2,PDYN,SERPINI1,FTO,PLP1,PPARA,PPP2R2B,PRKAR1B,RELN,PTHLH,RAB3A,LRRK2,S100B,ATXN1,ATXN2,ATF7IP,SNCB,SNCA,WDTC1,SPP1,LMO3,CLSTN2,VPS13A,SYP,ASTN2,WWC1,ATP13A2,SMUG1,TRPM2,UCHL1,TOM1L2,VLDLR,WNK1,LRP8,EPM2A,JPH3" Disease C0575081 Gait abnormality DisGeNET Curated 6.44E-05 7.95E-01 7.57E-03 7.56E-02 42 137 "KLRC4,ADCY5,KCNAB2,APP,CASK,PDE8B,ATM,CA8,CACNA1B,LARGE1,CFL2,COL9A1,COL9A2,COL9A3,KIAA0586,GNE,FKTN,POMT1,ERAP1,ATP8A2,MMADHC,PRDM5,IL12A,L1CAM,MATN3,MTR,MYH7,OPA1,TREM2,PMP22,APTX,SBF1,SLC6A8,SLC20A2,ELOVL4,VAMP1,VPS13A,RPGRIP1L,TLR4,TTPA,VLDLR,EPM2A" Disease C0009952 Febrile Convulsions DisGeNET Curated 6.70E-05 8.26E-01 7.79E-03 7.79E-02 22 56 "SLC12A5,PCDH19,APP,HCN2,ZBED1,CHRNA4,CNR1,DYRK1A,SEZ6,ADGRV1,FGF13,GABRA1,GABRB3,GABRG2,KCNQ3,HCN1,PRRT2,STX1B,SCN2A,SOX2,STXBP1,SLC30A3" Disease C0037019 Shy-Drager Syndrome DisGeNET Curated 8.39E-05 1.00E+00 9.67E-03 9.67E-02 27 76 "SERPINA3,FBXO7,SNCAIP,CST3,DCTN4,ABCA8,FYN,GFAP,TPPP,HRH3,IGF1,MAP2,MAPT,MBP,PLP1,POLG,APTX,PTHLH,LRRK2,ATXN1,SYBU,SIRT2,SNCA,SPP1,LMO3,TLR4,UCHL1" Disease C1136249 "Mental Retardation, X-Linked" DisGeNET Curated 9.11E-05 1.00E+00 1.04E-02 1.04E-01 35 109 "PTCHD1,NLGN4X,PCDH19,CASK,CHM,ABCG2,COL4A5,DLG3,RAB39B,MED12,GPHN,ACSL4,KIAA1109,FGF13,AFF2,IL1RAPL1,ZDHHC15,AGFG1,L1CAM,OCRL,OPHN1,PAK3,POU3F4,FAM120C,IL17RB,ARX,SLC6A8,SMARCA4,SOX3,IQSEC2,ARHGEF9,SYP,ZNF711,FTSJ1,WNK3" Disease C0037036 Sialorrhea DisGeNET Curated 1.05E-04 1.00E+00 1.18E-02 1.18E-01 14 29 "ATP1A3,CA12,AP4M1,NRXN1,ZEB2,FOXG1,PAK3,QDPR,SETD5,SPART,VPS13A,TAC1,AP4E1,UBE3A" Disease C0085281 Addictive Behavior DisGeNET BeFree 1.09E-04 1.00E+00 1.22E-02 1.22E-01 57 207 "ALK,ATM,CALM1,KALRN,SLC16A4,CHRNA4,NRXN3,CNR1,SLC4A7,CLOCK,CRHBP,ZNF804A,CNIH3,DRD1,EGFR,ERBB2,ERBB4,SEC23B,GABBR1,GABRA2,C1QL1,GLS,GLUL,NR3C1,GRM2,GRM3,GRM5,GABARAPL2,TLX1,HSP90AA1,IGF1,KIT,LMO1,MITF,MYCN,MYH6,MYO6,NFE2L2,NRCAM,NTRK2,PDGFRA,PDYN,ABCB1,PIK3CD,FTO,MAPK3,MAPK7,ROBO1,YY1AP1,ASRGL1,SLC6A1,LMO3,VPS13A,NR2E1,CSMD1,FIP1L1,PCBP4" Disease C0008489 Chorea DisGeNET Curated 1.16E-04 1.00E+00 1.29E-02 1.29E-01 21 54 "ADCY5,PLA2G6,SGCE,LGI1,CACNA2D2,CLCN3,FBXO7,CP,PNKD,FOXG1,TREM2,PRODH,APTX,PRRT2,ATXN1,ATXN7,SLC6A8,SLC20A2,SST,VPS13A,TAC1" Disease C0262404 Cerebellar degeneration DisGeNET Curated 1.18E-04 1.00E+00 1.30E-02 1.30E-01 41 136 "PLA2G6,APP,ATM,KIF1A,BCS1L,CACNA1A,CAST,RUNX1T1,AP4M1,ARHGEF2,CDR1,NOP56,GABRA3,ATP8A2,PCLO,GRM1,KCND3,KCNJ10,MYH3,OPA1,PDYN,POLG,PPP2R2B,PRKCG,APTX,PEX2,ATXN1,ATXN2,FOXRED1,CCDC88A,SOX3,SPTAN1,SPART,SYNE1,AP4E1,PIK3R5,TRPC3,UCHL1,VLDLR,ZIC1,AAAS" Disease C0424295 Hyperactive behavior DisGeNET Curated 1.34E-04 1.00E+00 1.46E-02 1.46E-01 189 866 "ACHE,ADAR,ADCY5,ADCY8,ADORA2A,ADORA3,PTCHD1,ADRB2,NR0B1,PLA2G6,ALK,AMT,OGT,ANK3,APC,APP,PTCH2,ATM,BCHE,BLM,PROM1,CALM1,CARS,CBS,CCK,CCKBR,CD38,CDC42,NRXN1,CLU,FADS2,ABCG2,COL11A2,PNKD,NCOR1,RGS6,FEZ1,CNTNAP2,CYBB,DAPK1,WDR20,DMD,DNM1,MED12,DNM2,DRD1,DYRK1A,DNM1L,EDN1,EEF1A2,EGFR,AASS,BSCL2,ERBB2,ERBB4,TLR7,CEND1,FABP7,PTK2B,FKTN,FGFR3,FOXM1,FOXO3,FLT1,AFF2,OGA,GAB1,GABBR1,GABRA2,GABRB3,TRAF3IP2,ATP8A2,GCK,C1QL1,GJB1,HPGDS,GLDC,GLS,GNAS,STON1,GRIA1,GRIA2,ADAMTS13,GRIN1,NR3C1,GRM1,GRM5,GRM7,IL1RAPL1,FAM107A,HLF,HTR2A,IGF1,IL6ST,JAK2,KCNJ5,KCNK2,KIT,MAP6,MAPT,MATK,IL17D,MEF2C,KITLG,MITF,GIT1,MYCN,MYO5A,NF1,NFIA,NFE2L2,NFIX,NOS1,NPY,NPTX2,NTRK2,OPHN1,OXTR,P2RX7,P2RY1,PAH,PAK3,PBX1,PDE4D,PDYN,ABCB1,PIK3CD,PKD1,PLTP,PMP22,PPARA,MED1,PTPA,MAPK3,MAPK8,MAPK9,MAPK10,PRODH,PTCH1,RAB3A,PRRT2,RPS6KA2,LRRK2,RYR1,S100B,ATXN2,SCN8A,PEAR1,CASC3,ASRGL1,SH3BP2,SLC6A8,SLC8A1,SNAP25,SNRPN,WDTC1,SOX11,IQSEC2,SPART,LMO3,SST,ABCC8,VPS13A,SYT1,TAC1,TACR1,DMXL2,SATB2,TEK,TLR4,TP53BP1,SMUG1,TRH,CA14,TSC1,ANO5,TSC2,UBE3A,UCHL1,GORASP1,VAV1,WRN,ELFN1,WNK1,CADM2,TUBA1A,DOCK8,NUP214,NLRP3" Disease C1258666 Myxoid cyst DisGeNET BeFree 1.36E-04 1.00E+00 1.48E-02 1.47E-01 56 204 "ACHE,ALK,NGB,CAST,CCK,CLU,COL11A2,CRMP1,CHD5,DNM1L,EDN3,OPTN,FGF1,FLT1,DKK3,GAD1,GAD2,CYP46A1,GFAP,GFRA1,PRUNE2,STMN2,GRM7,LINGO1,CPT1C,IGF1,KCNA2,LAMA2,MAPT,MBP,IL17D,MOG,MTTP,MYCN,NEUROD1,OPA1,RETREG1,GPSM2,PTHLH,RET,RGR,ATXN2,ATXN7,NLGN1,SLC1A3,SOX10,MCF2L2,SST,SSTR2,SYP,SYT1,TAC1,SIK3,SIRT1,VSNL1,ZIC2" Disease C0026351 Moderate mental retardation (I.Q. 35-49) DisGeNET Curated 1.43E-04 1.00E+00 1.53E-02 1.53E-01 17 40 "ANK3,CASK,RUNX1T1,RTTN,PREPL,ZEB2,TUBB3,AFF2,IL1RAPL1,MAN1B1,KCNJ10,KCNQ2,PDE4D,PPM1B,DMXL2,RPGRIP1L,ZIC1" Disease C1866195 Downturned corners of mouth DisGeNET Curated 1.46E-04 1.00E+00 1.55E-02 1.55E-01 20 51 "NIPBL,HDAC4,EEF1A2,CHL1,CPLX1,GCK,SRCAP,GK,PCLO,HNRNPK,KCNH1,KCNJ11,MEF2C,MAGEL2,MASP1,SNRPN,ABCC8,NSD2,MKRN3,KAT6A" Disease C3840214 High-functioning autism DisGeNET BeFree 1.50E-04 1.00E+00 1.58E-02 1.58E-01 6 7 "CLOCK,CNTNAP2,SHANK1,IL1RAPL1,OXTR,STX1A" Disease C0270850 Idiopathic generalized epilepsy DisGeNET Curated 1.58E-04 1.00E+00 1.65E-02 1.65E-01 21 55 "SLC12A5,HCN2,DST,CACNA1G,NIPA1,CACNB4,LGI1,NRXN1,SLC12A6,GPHN,GABBR1,GABRA1,GABRB3,GABRG2,HP,KCNQ2,KCNQ3,HCN1,SCN2A,SLC4A3,LGI4" Disease C0236736 Cocaine-Related Disorders DisGeNET Curated 1.75E-04 1.00E+00 1.82E-02 1.82E-01 34 108 "LRRC7,SYT13,BCHE,CALM1,CAMK2A,CAMK2B,CCKBR,SCARB1,CNR1,CRHBP,GPSM1,HDAC4,DRD1,KLHL5,GPHN,FDFT1,GABBR1,GABRA2,GABRG2,GAD1,GAD2,GRIA1,GRIA2,GRIN1,NR3C1,GRM5,HTR2A,NPY,NTRK2,PDYN,MAPK3,SLC1A2,SNCA,ARC" Disease C1847987 HUNTINGTON DISEASE-LIKE 2 DisGeNET Curated 1.86E-04 1.00E+00 1.90E-02 1.90E-01 8 12 "RIMS2,MBNL2,MBNL1,PPP2R2B,VPS13A,TK2,NELFE,JPH3" Disease C0338430 Limbic Encephalitis DisGeNET BeFree 1.86E-04 1.00E+00 1.90E-02 1.90E-01 8 12 "BRSK2,LGI1,CNTNAP2,DPYSL4,GABBR1,GRM5,ARHGAP26,DPYSL5" Disease C0236969 Substance-Related Disorders DisGeNET Curated 1.92E-04 1.00E+00 1.94E-02 1.94E-01 36 117 "XKR4,CSMD3,ADARB2,BCAR3,ANK3,NRXN3,CNR1,AKAP7,CHD1L,ZNF804A,TIAM2,DSCAM,FAM184B,GRIA4,GRIK2,GRM5,GRM7,KLF12,LDLRAD3,MSRA,CTNNA3,MYO6,NPY,NRCAM,PBX1,PDE1C,FAM184A,SEMA6D,CSRNP3,FHOD3,LIMCH1,ANO4,SYNE1,CSMD1,PCDH15,CERS6" Disease C0085648 Synovial Cyst DisGeNET BeFree 1.96E-04 1.00E+00 1.96E-02 1.96E-01 55 202 "ACHE,ALK,NGB,CAST,CCK,CLU,COL11A2,CRMP1,CHD5,DNM1L,EDN3,OPTN,FGF1,FLT1,DKK3,GAD1,GAD2,CYP46A1,GFAP,GFRA1,PRUNE2,STMN2,GRM7,LINGO1,CPT1C,IGF1,KCNA2,LAMA2,MAPT,MBP,IL17D,MOG,MTTP,MYCN,NEUROD1,OPA1,RETREG1,GPSM2,PTHLH,RET,RGR,ATXN2,ATXN7,NLGN1,SLC1A3,SOX10,MCF2L2,SST,SSTR2,SYP,SYT1,TAC1,SIK3,SIRT1,ZIC2" Disease C0856975 Autistic behavior DisGeNET Curated 2.12E-04 1.00E+00 2.11E-02 2.11E-01 15 34 "PTCHD1,NLGN4X,NRXN1,SH2B1,CNTNAP2,DNM1,TBR1,GABRB3,HTR2A,MEF2C,MAPK10,NLGN4Y,SLC6A8,ZNF423,SYN1" Disease C0026826 Muscle Hypertonia DisGeNET Curated 2.14E-04 1.00E+00 2.11E-02 2.11E-01 29 88 "LARGE1,CRLF1,ADGRG1,NIPBL,CP,DBT,DMPK,GPHN,ERCC2,EYA1,FKTN,POMT1,GALC,TUBGCP4,GLRB,KCNQ2,KCNQ3,MYO5A,OGDH,PAH,PSAT1,PMS2,POLG,QDPR,SCN2A,SCN8A,SLC6A8,SOX10,ARHGEF9" Disease C0233794 Memory impairment DisGeNET Curated 2.18E-04 1.00E+00 2.14E-02 2.14E-01 60 226 "ACHE,ADORA2A,PLA2G6,BIN1,ANK3,APP,CDK5R1,CHRNA4,CHRNB2,CNR1,CSF1,CSF1R,CX3CR1,CYBB,HDAC4,SHANK1,ATN1,DYRK1A,APH1A,FGF14,OGA,CPLX2,CPLX1,GFAP,PPARGC1A,TTBK1,TPPP,GRIA1,GRM5,HTR2A,MAPT,AFF1,NCAM1,NEFM,NFE2L2,PAH,TREM2,PDE4A,PDE4D,GPR85,PTPA,PRKCG,MAPK3,MAPK8,RELN,PTPRZ1,S100B,NLGN1,SLC20A2,VAMP1,VPS13A,WWC1,CRTC1,SIRT1,THRA,CDK20,TRPM2,TTC3,SLC30A3,PCBP4" Disease C0424605 Developmental delay (disorder) DisGeNET BeFree 2.25E-04 1.00E+00 2.18E-02 2.18E-01 48 171 "PCDH19,APC,NRXN1,SH2B1,HDAC4,DMD,DPH1,DYRK1A,CEND1,FGFR3,FOXG1,NRG3,AHDC1,GLRB,GNAO1,GP1BB,GRM7,IGF1,KCNJ11,KCNQ2,LIG4,MAOB,MAPT,MBP,MEF2C,NF1,NTRK2,OPHN1,FTO,PLP1,PMP22,POU3F2,PTCH1,ALG9,SLC6A7,WDTC1,SOX3,EMC1,POGZ,NKAIN2,STXBP1,ABCC8,CAMTA1,TCF4,DICER1,ASXL3,UBE3A,UBE3B" Disease C1334953 Neuroblastic Tumor DisGeNET BeFree 2.53E-04 1.00E+00 2.44E-02 2.44E-01 19 49 "KIDINS220,ALK,ASPH,CHD5,ARHGAP24,DAPK3,ZMYND10,STMN2,ITGAV,KIT,KITLG,MYCN,NCAM1,PTHLH,RET,SPP1,TGFBR3,SMUG1,MAP3K12" Disease C1839764 Broad flat nasal bridge DisGeNET Curated 2.68E-04 1.00E+00 2.54E-02 2.54E-01 62 237 "RBM10,ARID1A,LTBP4,KCNAB2,CASK,PTCH2,BBS2,PROM1,CA4,SEC24C,CTNND2,MED12,SLC12A6,GNE,ABCC9,EDN3,EDNRA,EDNRB,ELN,ERCC2,FGFR1,CPLX1,TUBGCP4,SRCAP,GLUL,GP1BB,HBA1,MAN1B1,IDH3B,KCNH1,LIG4,MID1,MITF,MYCN,MYH3,PDE4D,PIK3R1,PTCH1,PEX2,PEX5,RGR,RLBP1,ROM1,RPE65,PUF60,PEX26,RAB3GAP1,SMARCA4,SMARCE1,SOX10,SOX11,TCF4,CRB1,AP4E1,TPM2,TUB,HIRA,BEST1,CLIP2,NSD2,WNT7A,XRCC4" Disease C1849367 Nasal bridge wide DisGeNET Curated 2.68E-04 1.00E+00 2.54E-02 2.54E-01 62 237 "RBM10,ARID1A,LTBP4,KCNAB2,CASK,PTCH2,BBS2,PROM1,CA4,SEC24C,CTNND2,MED12,SLC12A6,GNE,ABCC9,EDN3,EDNRA,EDNRB,ELN,ERCC2,FGFR1,CPLX1,TUBGCP4,SRCAP,GLUL,GP1BB,HBA1,MAN1B1,IDH3B,KCNH1,LIG4,MID1,MITF,MYCN,MYH3,PDE4D,PIK3R1,PTCH1,PEX2,PEX5,RGR,RLBP1,ROM1,RPE65,PUF60,PEX26,RAB3GAP1,SMARCA4,SMARCE1,SOX10,SOX11,TCF4,CRB1,AP4E1,TPM2,TUB,HIRA,BEST1,CLIP2,NSD2,WNT7A,XRCC4" Disease C0476254 Dyslexia DisGeNET Curated 2.83E-04 1.00E+00 2.66E-02 2.66E-01 27 81 "KCNH8,SEMA6A,DGKI,ARHGEF2,SLIT2,CNTNAP2,NRSN1,RIMS2,DOCK4,ZNF804A,KIAA0319,GABBR1,PCDH11X,HMGB1,LRRTM1,MAPT,MOG,NRGN,TREM2,ROBO1,SFPQ,DIP2A,TACR1,TCF4,TNFRSF1B,NELFE,EPM2A" Disease C0730362 Disorder of macula of retina DisGeNET Curated 2.90E-04 1.00E+00 2.69E-02 2.69E-01 17 42 "PROM1,FADS2,CX3CR1,EDN3,EDNRB,EFEMP1,KCNMA1,BCO1,NDP,DRAM2,RPE65,ATXN7,SOX10,ELOVL4,CRB1,TST,BEST1" Disease C0206718 Ganglioneuroblastoma DisGeNET Curated 2.90E-04 1.00E+00 2.69E-02 2.69E-01 17 42 "ALK,ASCL1,EDN3,EGFR,EFS,PDLIM5,GAP43,WASF3,ITGAV,MYCN,NCAM1,NPY,NTRK2,PTHLH,RET,SST,TAC1" Disease C1836003 Facial diplegia DisGeNET Curated 3.14E-04 1.00E+00 2.89E-02 2.89E-01 7 10 "ADCY6,CNTNAP1,DMPK,SLC12A6,TK2,TPM2,TPM3" Disease C1854494 Slow progression DisGeNET Curated 3.30E-04 1.00E+00 2.99E-02 2.99E-01 29 90 "PDE8B,KIF1A,CFL2,FBXO7,DCTN1,DNM2,DNAJB6,BSCL2,REEP2,FGF14,FLNC,POMT1,AP4B1,GJB1,GRM1,GYG1,HPCA,KCND3,MYH7,PDYN,RETREG1,PLP1,PMP22,PRKCG,PEX2,RYR1,KIF1B,SYNE1,GAN" Disease C0027746 Nerve Degeneration DisGeNET Curated 3.32E-04 1.00E+00 2.99E-02 2.99E-01 36 120 "ADORA1,ADRA1B,PLA2G6,APP,CDK5R1,CDH2,CHRNB2,CNR1,CP,MATR3,DCTN1,OPTN,ERBB4,GALC,PPARGC1A,GRIN2D,PTPN5,IGF1,KCNJ4,NEFH,NOS1,OGG1,TREM2,MAPK3,PRPH,LRRK2,ATXN2,SLC1A2,SNCA,AGTPBP1,ATP13A2,SIRT1,ZMAT3,TSC2,UCHL1,LRP8" Disease C0014474 Ependymoma DisGeNET Curated 3.32E-04 1.00E+00 2.99E-02 2.99E-01 36 120 "PROM1,ABCG2,ARHGAP24,DAPK1,EGFR,OLIG2,ERBB2,FCGR1A,FLT1,GFAP,JAK2,KIT,LAMA2,STMN1,MAP2,SHC3,MYCN,NF1,PDGFRA,ABCB1,PIK3CD,PMS2,RAB3A,RFX3,ZFHX4,S100B,SOX10,SOX11,BEX1,SST,EPB41L3,SYP,ZEB1,HEY2,TSC1,TSC2" Disease C0333463 Senile Plaques DisGeNET BeFree 3.47E-04 1.00E+00 3.09E-02 3.08E-01 77 311 "SERPINA3,ACHE,NDRG2,NR0B1,SEMA6A,APBA2,APBB1,APBB2,APLP1,APP,BCHE,SYNJ1,DDR1,CALB1,SLC25A14,CAST,RUNX1T1,CDR1,CHRNA4,TAOK2,CLU,ABCG2,RIMS2,DSCAM,RCAN1,SEZ6L2,APH1A,DCTN4,ENO2,OLFM1,FLT1,OGA,GAP43,CYP46A1,GFAP,PPARGC1A,HPGDS,GLUL,ADAP1,STMN2,HSP90AA1,HTR2A,ATCAY,IGF1,MAP2,MAPT,MBP,MT3,MX1,NRDC,OLR1,TREM2,PDYN,ABCB1,DUSP26,RELN,RAB3A,ATG16L1,NUDT11,S100B,SYBU,SNCA,ABCC8,SYN1,SYP,TF,THBS4,TLR4,SMUG1,VLDLR,VSNL1,SLC30A3,WNK1,PCBP4,NELFE,UBE3B,NUP214" Disease C0151611 Electroencephalogram abnormal DisGeNET Curated 3.50E-04 1.00E+00 3.09E-02 3.08E-01 32 103 "KCNAB2,ASPA,ALDH7A1,BCS1L,LARGE1,RTTN,SH2B1,SLC12A6,AASS,EMX2,ERCC2,FKTN,FOXG1,POMT1,GABRA1,GABRG2,GALC,OCRL,TREM2,PRODH,PEX2,PEX5,SCN2A,NTNG1,PEX26,SNRPN,STXBP1,CNTN2,SZT2,TSC1,TSC2,UBE3A" Disease C0234979 Dysdiadochokinesis DisGeNET Curated 3.50E-04 1.00E+00 3.09E-02 3.08E-01 12 25 "PLA2G6,PDE8B,GRM1,KCNJ10,PPP2R2B,ATXN1,ATXN2,SLC20A2,ELOVL4,TTPA,VLDLR,XRCC4" Disease C0085583 Choreoathetosis DisGeNET Curated 3.63E-04 1.00E+00 3.17E-02 3.17E-01 16 39 "ATM,ATP1A2,ATP1A3,ST3GAL5,ATN1,ERCC2,GLDC,KCNQ2,KCNQ3,PLP1,POLG,APTX,QDPR,PRRT2,SCN2A,SCN8A" Disease C0004114 Astrocytoma DisGeNET Curated 3.84E-04 1.00E+00 3.34E-02 3.34E-01 158 721 "ACHE,ACTN1,NDRG2,SEMA6A,ALK,APC,APP,AQP4,CDC14B,ASCL1,NCOA1,ATM,CDK5R1,ARHGEF7,FUBP1,BTRC,CA12,DIRAS1,CALM1,SPAG9,CCK,CCNT1,SLC16A4,AIFM1,NEURL1,SEPT7,CDC42,LGI1,CLU,CNR1,PICK1,AKAP12,CS,RGS6,CSF3R,VCAN,CST3,RIMS2,CX3CR1,ARHGAP24,SIRPA,DNM2,ATN1,DNM1L,EDN1,EDNRA,EDNRB,EGFR,ING4,BSCL2,OLIG2,ERBB2,EZH1,F3,FABP7,CHST15,ZMYND10,PRMT5,FGFR1,FLT1,FOLH1,DLL3,B3GAT1,DKK3,GAP43,ALDH1L1,GPR162,GFAP,HPGDS,GRM5,PTPRT,GSN,WIF1,IGF1,HES5,IL12A,JAK2,KCNH2,STMN1,MATK,MBP,MDM4,SHC3,MMP16,CTNNA3,MXI1,NCAM1,NF1,NKX2-2,NPY,NOVA1,NTRK2,P2RX7,P2RY1,PAX6,PDE3B,PDGFRA,PFKFB3,SERPINE2,PIK3CD,PIK3R1,PLEC,FTO,PLP1,SEPT4,PPP1R1A,MAPK3,MAPK8,KLK6,PTHLH,PTK2,PTN,PTPN13,PTPRZ1,PID1,RASGRF1,PRRT2,RGS3,RGS4,WLS,S100B,HES6,SCG5,SLC1A2,SLC6A8,CPEB4,SMARCA4,SNRPN,WDTC1,SOX2,SOX10,SOX11,SPP1,NPAS3,SST,STX1A,MLC1,TAC1,TACR1,CAMTA1,CNTN2,TCF4,TCF7L2,PCDHGA11,AZIN2,PSD3,TEK,HEY1,TIMP4,HEY2,TPM3,TRH,TSC1,TSC2,VAV2,XRCC4,SPHK2,NELFE" Disease C0234533 Generalized seizures DisGeNET Curated 3.97E-04 1.00E+00 3.42E-02 3.42E-01 11 22 "PCDH19,ASPA,SYNJ1,LGI1,FGFR3,GABRB3,KCNB1,NFE2L2,SCN8A,PLCB1,CNTN2" Disease C0040517 Gilles de la Tourette syndrome DisGeNET Curated 4.06E-04 1.00E+00 3.47E-02 3.47E-01 29 91 "SLITRK1,ADD2,ADORA1,ADORA2A,NLGN4X,APBA2,ARNTL,SGCE,CDH2,DLGAP3,NRXN1,CNR1,CNTNAP2,OLIG1,DPP6,DRD1,OLIG2,PDLIM5,OGA,HTR2A,KCNJ5,MEIS1,MOG,SKOR1,ALG9,LMO3,ROBO3,UBE3B,CBLN2" Disease C0546264 Congenital Fiber Type Disproportion DisGeNET Curated 4.12E-04 1.00E+00 3.50E-02 3.50E-01 8 13 "MYH7B,CD38,DMPK,ITGA7,MYH7,RYR1,TPM2,TPM3" Disease C0497327 Dementia DisGeNET Curated 4.39E-04 1.00E+00 3.71E-02 3.71E-01 93 392 "SERPINA3,ACHE,KIDINS220,PLA2G6,ALK,BIN1,APOC1,APP,BCHE,SYNJ1,RUNX1T1,CD38,CDR1,CHM,CHRNA4,TAOK2,CLU,CP,SNCAIP,CSF1R,CST3,PLXNA4,DCTN1,DNM2,ATN1,DSCAM,DYRK1A,SEZ6L2,EEF1A2,EIF4G1,ENO2,PTK2B,FYN,GAP43,GFAP,PPARGC1A,HPGDS,GLS,NR3C1,WIF1,HTR2A,IGF1,IL6R,MAPT,MEF2C,NDP,NF1,NINJ2,NOVA2,NTRK2,OPA1,TREM2,PDYN,PENK,SERPINI1,PIK3CD,FTO,PLP1,POLG,PPARA,PPP2R2B,PRKAR1B,RELN,PTHLH,RAB3A,LRRK2,S100B,ATXN1,ATXN2,SFPQ,ATF7IP,SNCB,SNCA,WDTC1,SPP1,LMO3,CLSTN2,VPS13A,SYP,ASTN2,TAC1,WWC1,ATP13A2,TIMP4,SMUG1,TRPM2,UCHL1,TOM1L2,VLDLR,WNK1,LRP8,EPM2A,JPH3" Disease C0236733 Amphetamine-Related Disorders DisGeNET Curated 4.68E-04 1.00E+00 3.92E-02 3.92E-01 25 75 "ACHE,ADORA2A,ARRB2,LARGE1,PICK1,AK5,HS3ST4,DRD1,RGS17,PCOLCE2,GABRG2,GRM2,COL28A1,NOS1,PDE4B,PDE4D,PDYN,SLC6A9,SNCA,ZNF423,ASTN2,ACSL6,PSD3,CSMD1,PRDM2" Disease C0494475 Tonic - clonic seizures DisGeNET Curated 4.85E-04 1.00E+00 4.04E-02 4.04E-01 23 67 "ATP1A2,ALDH7A1,SYNJ1,ST3GAL5,CACNA1D,LGI1,DNM1,GPHN,GABRB3,GABRG2,GCK,KCNJ11,KCNMA1,KCNQ2,KCNQ3,POLG,MAPK10,SCN2A,STXBP1,ABCC8,CNTN2,NPL,EPM2A" Disease C2981150 Uranostaphyloschisis DisGeNET Curated 5.13E-04 1.00E+00 4.24E-02 4.24E-01 56 214 "DGCR6,RBM10,PTCH2,LARGE1,NIPBL,COL9A1,COL9A2,COL9A3,COL11A2,SLC32A1,SEC24C,KIAA0586,B3GAT3,ARNT2,MED12,WDPCP,EDNRA,EYA1,FKTN,FGFR1,FOXF2,POMT1,STAMBP,TBR1,CHL1,GABRB3,SEPT9,CPLX1,TXNL4A,GLI2,GP1BB,ZNF385B,MEIS2,MID1,MN1,NEK1,NHLH1,PSAT1,PRRX1,MASP1,PTCH1,PEX2,PEX5,KIF7,RPL15,SOX2,SOX3,SOX11,SPP1,SMOC1,TBX15,SATB2,RPGRIP1L,TNS1,HIRA,NSD2" Disease C0338451 Frontotemporal dementia DisGeNET Curated 5.71E-04 1.00E+00 4.65E-02 4.65E-01 40 141 "ACHE,CDC7,APOC1,APP,BCHE,PTBP2,CAMK2A,CBS,INA,MAP4K4,RIMS2,DAPK1,DCTN1,GNE,OPTN,ELAVL2,DCTN4,FLNC,PDLIM5,GAP43,RNPS1,MAPT,NEFM,NEFH,TREM2,PENK,PRKAR1B,MAPK3,LRRK2,ATXN2,SYBU,SNAP25,SNCA,SST,TTBK2,SYN1,SMUG1,NELFE,NUP214,AAAS" Disease C0027796 Neuralgia DisGeNET Curated 5.74E-04 1.00E+00 4.65E-02 4.65E-01 30 97 "SLC12A5,APP,PRX,CACNA2D1,CNR1,CX3CR1,DPYSL2,GAD1,GAD2,GFRA1,GFRA2,GGTA1P,GRM2,GRM5,HMGB1,SLC35G1,KCNA2,HCN1,P2RX7,POLG,PRKCG,ATAT1,SLC1A2,SLC6A9,MCF2L2,TAC1,TACR1,THBS4,TLR4,P2RY12" Disease C0240543 Bulbous nose DisGeNET Curated 5.88E-04 1.00E+00 4.65E-02 4.65E-01 18 48 "DGCR6,AP4M1,COL11A2,SMARCAL1,SEC24C,MED12,ABCC9,FOXG1,AP4B1,SRCAP,GP1BB,AP4S1,CAMTA1,SATB2,OBSL1,AP4E1,TRPS1,HIRA" Disease C1834118 Potato nose DisGeNET Curated 5.88E-04 1.00E+00 4.65E-02 4.65E-01 18 48 "DGCR6,AP4M1,COL11A2,SMARCAL1,SEC24C,MED12,ABCC9,FOXG1,AP4B1,SRCAP,GP1BB,AP4S1,CAMTA1,SATB2,OBSL1,AP4E1,TRPS1,HIRA" Disease C1855751 Bulbous nasal tip DisGeNET Curated 5.88E-04 1.00E+00 4.65E-02 4.65E-01 18 48 "DGCR6,AP4M1,COL11A2,SMARCAL1,SEC24C,MED12,ABCC9,FOXG1,AP4B1,SRCAP,GP1BB,AP4S1,CAMTA1,SATB2,OBSL1,AP4E1,TRPS1,HIRA" Disease C1838869 Proximal neurogenic muscle weakness DisGeNET Curated 5.88E-04 1.00E+00 4.65E-02 4.65E-01 18 48 "MTMR2,LARGE1,COL9A3,DNM2,GNE,FKTN,FHL1,FLNC,GAA,LAMP2,MYH7,POLG,RYR1,SYNE2,SYNE1,TPM2,TPM3,GAN" Disease C0221629 Proximal muscle weakness DisGeNET Curated 5.88E-04 1.00E+00 4.65E-02 4.65E-01 18 48 "MTMR2,LARGE1,COL9A3,DNM2,GNE,FKTN,FHL1,FLNC,GAA,LAMP2,MYH7,POLG,RYR1,SYNE2,SYNE1,TPM2,TPM3,GAN" Disease C0236642 Pick Disease of the Brain DisGeNET Curated 6.06E-04 1.00E+00 4.76E-02 4.76E-01 29 93 "APOC1,APP,ST3GAL5,PTBP2,INA,CDC42,CHRNA4,MAP4K4,RIMS2,DYRK1A,OPTN,PDLIM5,GAP43,RNPS1,HPGDS,MAPT,NEFM,NEFH,TREM2,PENK,PRRX1,PRKAR1B,MAPK3,PTCH1,LRRK2,SFPQ,SNCA,NELFE,NUP214" Disease C1839758 Narrow forehead DisGeNET Curated 6.41E-04 1.00E+00 4.93E-02 4.93E-01 15 37 "AP4M1,SLC12A6,DYRK1A,ELN,AP4B1,MEIS2,MAGEL2,RBBP8,PUF60,CCDC88A,SNRPN,TCF4,AP4E1,MKRN3,KAT6A" Disease C1720189 Episodic Ataxia DisGeNET Curated 6.44E-04 1.00E+00 4.93E-02 4.93E-01 11 23 "ATP1A2,ATP1A3,CACNA1A,CACNB4,PNKD,FGF14,KCNA1,PRRT2,ATXN1,SCN2A,SLC1A3" Disease C0752203 "Dystonia, Primary" DisGeNET BeFree 6.44E-04 1.00E+00 4.93E-02 4.93E-01 11 23 "APP,ATP1A3,SGCE,TUBB4A,GABRB3,GABRG2,GNAL,PRRT2,LRRK2,SLC30A10,AAAS" Disease C0432040 "Simple syndactyly of toes, first web space" DisGeNET Curated 6.44E-04 1.00E+00 4.93E-02 4.93E-01 11 23 "BMPR1B,NOG,NIPBL,SLC12A6,GNE,FGFR1,TXNL4A,RBPJ,SALL1,SOX5,TBX15" Disease C1839839 MAJOR AFFECTIVE DISORDER 2 DisGeNET Curated 6.53E-04 1.00E+00 4.95E-02 4.95E-01 31 102 "ANK3,HIP1R,DCLK1,MAGI1,CLOCK,ABCG1,ZNF804A,MAGI2,DMD,TOM1,ERBB4,GAD1,MCHR1,NR3C1,GRM3,HTR2A,IGF1,KCNN3,KCNQ2,NCAM1,P2RX7,PTPA,PRKCZ,PBRM1,S100B,MLC1,TACR1,TCF4,CUX2,TNS1,NPL" Disease C0018798 Congenital Heart Defects DisGeNET Curated 6.55E-04 1.00E+00 4.95E-02 4.95E-01 56 216 "ARID1A,NR0B1,ATP2B2,CAPN3,CCNH,NIPBL,CCDC151,CST3,ZEB2,B3GAT3,MED12,DSCAM,RCAN1,DYRK1A,EDN1,EDNRA,SEMA3D,FSD1L,EGFR,ELN,EYA1,F3,PRKAG2,GCK,GDF1,HPGDS,GP1BB,IRF8,KCNJ11,MEF2C,MEIS1,MID1,MYH6,MYH7,NF1,NODAL,NTRK3,OPA1,ABCB1,PKD1,FSD1,MAPK3,PROX1,PEX2,PEX5,PUF60,SLN,SOX11,TAB2,MESP1,ABCC8,MGRN1,TEK,ZFPM2,HEY2,ZIC3"